LOCUS       DAOOJU010000001       144285 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_80_length_144285_cov_15.433232, whole genome shotgun sequence.
ACCESSION   DAOOJU010000001 DAOOJU010000000
VERSION     DAOOJU010000001.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 144285)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 144285)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..144285
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_80_length_144285_cov_15.433232"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     repeat_region   35..196
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=35..64
                     /rpt_unit_seq="atttcaatcctattttagtccgattcaaac"
     gene            complement(575..1678)
                     /gene="cas1b"
                     /locus_tag="PK679_00005"
     CDS             complement(575..1678)
                     /gene="cas1b"
                     /locus_tag="PK679_00005"
                     /inference="COORDINATES: protein motif:HMM:NF013984.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - endodeoxyribonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1b"
                     /protein_id="HPC54378.1"
                     /translation="MKQNFYILKNGKIVRKQNTVYFISRKNDANTAFTAQCEDPDFIE
                     EFDGEEHNPEVPDVSDREGYEKRALPVEQIGAIFAYGRVSITSGVVSFLAKNAIPVHF
                     FGYYGQYESTLLPKESLLSGEMHLRQGQHYCDPEKRLFIARSFVSGAAQNMLKNLEYY
                     HNQEKNLSQVIKTIQSSLETVPVCQTIPELMAMEGKIRNAYYSVFDSILTSNFSFESR
                     SRRPPQNPVNAMISFGNSLMYGIVINAIYHTQLDQTISFLHEPSERRFSLALDIAEIF
                     KPLFVDRTIFKLVNKKMISDKDFEKDLQSCLMNDSGRRLFIAEFNNKMETTIKHRSLK
                     RNVSYGRLPYLECLKLCKHLLGLKKYEPFVIWW"
     gene            complement(1682..2197)
                     /gene="cas4"
                     /locus_tag="PK679_00010"
     CDS             complement(1682..2197)
                     /gene="cas4"
                     /locus_tag="PK679_00010"
                     /inference="COORDINATES: protein motif:HMM:TIGR00372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HPC54379.1"
                     /translation="MIKQLSRVQLTGTQINYYFVCPTKLWLFSHNISQESSSELVGMG
                     KFVHESSYSRENKNIIMDRIGIDFFKKGEGITIHEIKKSKKLEQAHRYQLYYYIYYLQ
                     EILDIPNVDGLLDYPLIRKRERLMLTDEVKKEIERILLEVNEIVKQPQSPPPIEKPYC
                     RKCAYFELCWV"
     gene            2279..3655
                     /gene="cas8a1"
                     /locus_tag="PK679_00015"
     CDS             2279..3655
                     /gene="cas8a1"
                     /locus_tag="PK679_00015"
                     /inference="COORDINATES: protein motif:HMM:TIGR01908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HPC54380.1"
                     /translation="MILESISKPKSQTKRKNGDPFVEIGILAIELITKKNFETCTTQD
                     LQRAADTLIEIFLTPAWKKELISIFPNSTYIQTSRGYNHRERSREFLYSLIEGISPSS
                     ESKTYCCFCGAQAYEKMRFYKTQIPLIGSGKFANYFPSFQNGLNICAKCALAIQFAPL
                     LCYKAGGKPCLISSNNRELLREFGKDICKTIKTRLASGEYNSQENSGLFDEKFKSPQN
                     ALFHLAYKFGREYCARGICSNNESIVLYHIDNYNQGPAGVRIYSLPSNIFKFVSFMMN
                     SPDYRSAWFSLLARYYPKSTDEEDLPIWKTKINPIHTYLLEGKNILWAFKDDRTRTVT
                     MPWPVVEGYMRSVRLMNQQRIEKIREFSDKIALSIRESKKFSRVHDIANARDLPSFRN
                     QLNLIVKDWQKLGKGEPIITFDDYIRILIPGDYRGWTEVRDLIVIRLYEKLHDILVKE
                     DENSEVTE"
     gene            3652..4686
                     /gene="cas7i"
                     /locus_tag="PK679_00020"
     CDS             3652..4686
                     /gene="cas7i"
                     /locus_tag="PK679_00020"
                     /inference="COORDINATES: protein motif:HMM:TIGR02585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HPC54381.1"
                     /translation="MKTIVGAYLIDAPFSALNNRGIDSRAANENEVATKTINSPEGPR
                     PYVSAQALRYWWRQILKNKFGWNCSPVEKIGSNQAITAADPIEYPDDDIFGYMSARKI
                     EVEGKKKPENITVTRVSPLKCSPLIGYPIRVTSDFGVMNRDFEGDPVLFNHQFYSNIL
                     KGIFALDLDAAGTFTAINKPGSMNLSPDLVKRCEEAGYSGRNDNKKYSLPLDMKVKRV
                     TDTIAALKYLNGGAMQTLHHTDVSPKFIILTALRGGNNIFMGVLPHRNYEEGLVNLDA
                     LTTVLEDYRNDLLTGVYIGLLPGFGTDNEKELMQFKAPEGVRLEINSPVRAIDGFIKE
                     ISGKSALFEA"
     gene            4689..5312
                     /gene="cas5b"
                     /locus_tag="PK679_00025"
     CDS             4689..5312
                     /gene="cas5b"
                     /locus_tag="PK679_00025"
                     /inference="COORDINATES: protein motif:HMM:TIGR01895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5b"
                     /protein_id="HPC54382.1"
                     /translation="MKVLRARIRAMTASFRYPMFMVAYQPTYSVPPISTVYGLLSAAK
                     GKKVHLHDIKVGYDFVSEGKGVDLERIHVYGGETRAHLGTDIVNREFLYNCCLTLYLS
                     DISFEEYLKYPRYSLLLGRQSDLAFVESVDTVELIEKEKIEIKNTIIPFNGEIPGQIV
                     SLPSDFTDEAERKPLNVMSYCIVDTPQIVEKGYFDPDRQTGVFLHEF"
     gene            5302..7494
                     /gene="cas3"
                     /locus_tag="PK679_00030"
     CDS             5302..7494
                     /gene="cas3"
                     /locus_tag="PK679_00030"
                     /inference="COORDINATES: protein motif:HMM:TIGR01587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HPC54383.1"
                     /translation="MNSELWAKSDGESLWDHTLSCLDVFLSLRDIFPDIDKKTNYMNF
                     YTDVFNALFFHDFGKAATGFQDQLRGGNRWHYRHEILSVPFVDALSSGDTDIIKLLIL
                     THHRDCRELIPYITQDDDPVSSPSFQDRVSEVKPNIEELKQLMRIYPQIARKYLGQDT
                     SIRPIDLNGYSADCWEKIIKTTSQCLNDEICRKRLKFIGIFGKGFVTSCDHLASGGIK
                     KVLKPLSSLDDVFRYSTYTSIQKKCRDIKGDALIISPTGSGKTEAALFWATANLDSLR
                     GNRIFYSLPYTASINAMYKRILKRIGPWYNDEGCVSLLHGRASYYLSRMYENGNGFGF
                     HKDIARKIYSPYKVMTPFQLLKHLFSIKGYEMGLLEMYRGIFILDEIHSYNAQTVGLI
                     LSMCEFLKSELEAKILLMSATLPEFIRKCFTDSLGIKSILTMDKDELDHYTRHKCSLL
                     DGNITDYIDCISDRINAGEKVLIVCNTVKQAQKIYNIFRNETINSALLHSKFILRDRE
                     QIERDISSLNMLVGTQAIEVSLDIDYDVCFSEPAPIDALIQRFGRVNRKRKKGICDVF
                     VFTHGSEQDSFIYDKEIVNNTLDELSNIDLLYEWLIQATVDKIYRDGFGKREKEFRDI
                     RHIFSQVIDEIVPFENADRSESDFYRLFNSIEAVPEAFRTDYLKCIKAGDVYSAMQYT
                     LPLGASQYHRLKRENRISTNEGMLFVNAKYDPKLGLLIEQRDPGAFTV"
     gene            complement(7484..8266)
                     /gene="cas6"
                     /locus_tag="PK679_00035"
     CDS             complement(7484..8266)
                     /gene="cas6"
                     /locus_tag="PK679_00035"
                     /inference="COORDINATES: protein motif:HMM:TIGR01877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HPC54384.1"
                     /translation="MRLLLTLKAEADQKDISLDYHKIQGFIYRMFQEGGYPGIHDKEG
                     YKYFCFSNVFPYGDMKEGDSRNFIISSPSTHLIDGLGKQIFAKMGSSIHIGDCSFSIQ
                     DCRRIAVSLPSPPVKIVCATPIILRIPERNYDLYGVPENERKPRYIYWRPSVSFEAFV
                     KQLSENLIKKYNEYYGTEVAHNNLFERFIFKKTVHTRIIIDGKSYGVAASLWEFSWNH
                     MDLLQKKIVRFGMDTGFGERNSYGFGFVNLVYSEKNSRPTIL"
     gene            complement(8890..9594)
                     /locus_tag="PK679_00040"
     CDS             complement(8890..9594)
                     /locus_tag="PK679_00040"
                     /inference="COORDINATES: protein motif:HMM:NF040371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6293 family protein"
                     /protein_id="HPC54385.1"
                     /translation="MTYTHIVFVGHHRERLIESITQYRKYPITRVVLVIGDDDTTGER
                     ISRKVATRVKSDLSPVYEVAIAKVDKRNVMNAASQVIDIILSERKDGRRCILNMSGSL
                     RTYAIAAYIAGCLTQSPMITSIPRYDEENREVGIEEIIELPTIPVQFPRKDQAELLGA
                     IAKSSGYLEDLILQANPRAREVPDELAKERSRLFHHLKKIEEMGFVTKERAGKQVMFS
                     LSPLGRIFAKVCRAEG"
     gene            10245..11306
                     /locus_tag="PK679_00045"
     CDS             10245..11306
                     /locus_tag="PK679_00045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54386.1"
                     /translation="MDTALESCLTSLRFEGGTIHGRMEVIPLFSGTHRGGDYLTLAQA
                     LAQNRLVITEVGESGTVPELMVRNRGKIPVLLIDGEELAGAKQNRVLNTTIIVPGESE
                     IVIPVSCTEHGRWSYTSPVFHDSEVMMDYRLRSKKMASVAMSRKFRGTLASDQLEIWD
                     DIGEMARKAKVHSRTGAMKDIFSAREKAMDEYMHAFPLQPGQQGILVYMDDQPAGMEF
                     LSRPESYARIHEKLLRSYVLEALIDDEAPPARAAGAERPAEFIQRVLFAHDEAYPGVG
                     LGTEHRLEGPDLVGSALVHEGLVVHLACFTGTSTGSCRAETRMAGFRARHGSRASGAG
                     GIPRNEKGRNREGEGIYES"
     gene            11296..12006
                     /locus_tag="PK679_00050"
     CDS             11296..12006
                     /locus_tag="PK679_00050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54387.1"
                     /translation="MNRDTKQAVWPWRGVRGRDPALPLTGRDRCIIVEEIGKMRDIPF
                     GAAVELLDQVLSGAIFSGGGKEPRREPPYAEYLGRLMYQVAARQDLAQEDRRLLMYRI
                     ASIGSEEDRARTAPNPVQGFFARLRAPDRGQDTGTGKEEDTLPLPRDLMVRLINGDKE
                     AFRALLGEDMERNLAFDEPGSSGKDPLRKGMENDIAGGDETGPGKKVRPKLTFEMWTL
                     EGDEVKITPLHSGEDEEE"
     gene            12003..13544
                     /locus_tag="PK679_00055"
     CDS             12003..13544
                     /locus_tag="PK679_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HPC54388.1"
                     /translation="MTFLTVLDGAQGIGGNKIHVEEKGKGLFLDFGKNFGKYGMYFEE
                     FLKNRDLRGIHDLMYLGLIPKLNIYRKDLVPSDLRVDSFPAPDVAAVLVSHAHVDHTG
                     NIGLLDLGIPVVASPLSLAIMKGMQDSGVSSVDTETSYASPRLPLDESGLMLRADKKI
                     PHTCRESICTTRPRDELVAFLSSRPGQEGPGAKKFEPAPCRSLDNVALPFAVTPYEVD
                     HSIVGATAYILRGDTTIAYTGDIRLHGRLGEKTRDFVHHAKDASVLIIEGTRAGPRER
                     SAAVTSEQTVYETCLADAEDQEGLIIADFSPRNFERMDTFSRIAQETGRTLVVTAKDL
                     YLLHALGCADGTCRYQGLGVYAELADIRKRKWETEVVMGKASHQYISHKELRNYPEEY
                     IACFSFFDIRHLLDIRPESGLYIYSACEAFSEEMEIDFRRLWQWIRRFGLEARGFAIR
                     DDGSPEFDSRYHASGHASADDLAWIIDQADPDVLVPVHTENHRWFAENFGGVRIVQDG
                     ERLTI"
     gene            13696..14646
                     /locus_tag="PK679_00060"
     CDS             13696..14646
                     /locus_tag="PK679_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HPC54389.1"
                     /translation="MPVTVQDASDTTAPSSLKARVYSMLEGDPESGGRAAWAIDLFLM
                     LLIIANVAATVLESVQSIADAYPAFFSGFEVFSVAVFSIEYVLRLWVCTENPAFAAAV
                     GGRLKYAATPLAIVDLFAVLPFYVPFLIPVDLRFMRVLRLMRIFRLLKLGRHSSALKF
                     VRNAFLKEKEALTIAAFVLVILVVFSSCLMFYLEHDAQPEAFTSIPQTMWWAVETLTT
                     VGYGDIIPVTPAGKVLGSFIAVLGIAMFAVPTGILAAAFLEEVRSQEGDREDDTDTAP
                     ETTIALLERLEGLRDRGVLSEEEFSDQKDRILGKRGGKKE"
     gene            complement(14672..15190)
                     /locus_tag="PK679_00065"
     CDS             complement(14672..15190)
                     /locus_tag="PK679_00065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54390.1"
                     /translation="MTDTAVIVFSRAGNTRKVADAIAAEPGVPVQDTNAPLPESARLV
                     FPGSGGYGGKPGEPLMQFIGSGNFSGRKAALSGTSGGAEGAQHMIAVMGMPSLRRVQR
                     SSAALRAAGSSSLPTGGIPAHRTSQMRRRLPGRWPGQRENLSTGFLPLLLRPGAITGC
                     SPRIRAGCDEGE"
     gene            complement(15482..15997)
                     /locus_tag="PK679_00070"
     CDS             complement(15482..15997)
                     /locus_tag="PK679_00070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54391.1"
                     /translation="MKFWFLEKFIIIGRIFPSIQEKRLESVISCTSSCRAEWKQEQDQ
                     EWNGEERREKMYTNVERRMRWLRIGPCDQDRVWGFFDEITGQAAEEQWVLIGQWYYFL
                     YVHDGRIDLCRTSVRKGQPALTEVISPGQYAISDDDLECAVHYWTCGTYEPGVYRISP
                     LIERKLRILFE"
     gene            complement(16071..16463)
                     /locus_tag="PK679_00075"
     CDS             complement(16071..16463)
                     /locus_tag="PK679_00075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54392.1"
                     /translation="MSSSPFLLSHPAKANSIKRAAGCRCEICGSTGTEDELEIHCFSG
                     EGEECPQSPEEMERSLLVLCARCHADLHASPDAVSGQELLAGARDREVSLRIRKILAF
                     QPGQVSPPDSDIEGAYKDACASRYGNLI"
     gene            complement(16794..17216)
                     /locus_tag="PK679_00080"
     CDS             complement(16794..17216)
                     /locus_tag="PK679_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HPC54393.1"
                     /translation="MPRKARERRGGGEGGRSAIPADMAASLARWGGIEGLVSAIPSAS
                     GLDAIKGLYLACSDAIRLKILFLLEKQPLCVCVIKAATGIADSRLSYHLQVLKKAGLI
                     EGDQQGNYIIYRITPSGKQILKDGRKYIRALSTGEDGR"
     gene            complement(17426..19039)
                     /gene="groL"
                     /locus_tag="PK679_00085"
     CDS             complement(17426..19039)
                     /gene="groL"
                     /locus_tag="PK679_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106636.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HPC54394.1"
                     /translation="MAQSKQLIFNEEARKLLLSGVNKVADTVKITLGPKGRYVVIDKP
                     TNPVVTNDGVTIAKEISLHDKFENIGAKLVKEVAQKTQDKTGDGTTTATLLVQAILTE
                     GLKNITSGGNPIEIKRGIDAAVSAAVDYIKSVSVPVNDRERIVQVATISANNDEEIGR
                     LISDAMEKVGYGGLITVEDAKSLETSLEVVKGMQFDRGFISPYMVTDHEKMTAEYEDP
                     SILVTDRRISTLKQMIPILEMAAQDGKPLLIIAEDVEGEALAALILNIIRGAVKVCAV
                     KAPGFGDERKALLEDIAILTGATVISEDRGMKIENVSRQSLGSAHTVRVDGEKTLIVG
                     GKGEKRALDERIKLIESQINISDSEFRKEELKKRLGNLTGGVAVIRVGAATETELKEK
                     KMRIDDALNATKAAVEEGVVPGGGITLFWAISALDSLHFDDDRKIGVSIVRRALEEPL
                     RQIARNAGVEGAEVIARIRNSNDRKFGYNAKTGTYENLMERGVIDPAKVVRVGLQNAA
                     SIAGMILSTEVAITDFDEEKDKKTAAIII"
     gene            complement(19047..19325)
                     /gene="groES"
                     /locus_tag="PK679_00090"
     CDS             complement(19047..19325)
                     /gene="groES"
                     /locus_tag="PK679_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HPC54395.1"
                     /translation="MEIVPIGERVLVKPIQGEERTKSGIYIPETAREQKKQGTVVSVG
                     SRDDGTPLPLKPGDHILYGGYSAETFEIDRETYVFVPFKDIVARIVRG"
     gene            19469..19876
                     /locus_tag="PK679_00095"
     CDS             19469..19876
                     /locus_tag="PK679_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HPC54396.1"
                     /translation="MVRGIILRQAERPVPGGGEDEVIWFCRCLGIGAGRDLDRVASRI
                     IIALLSSRAHDEGIPVEEIAHELAVTPARVNHHIRRLAEAGIVYRQKKRIFIRGRSLR
                     ALVQEIRKDALRILDDLEAAASEIDREYGIPHR"
     gene            20102..20578
                     /locus_tag="PK679_00100"
     CDS             20102..20578
                     /locus_tag="PK679_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HPC54397.1"
                     /translation="MAERSYHRIHDIFRRLLENIQDIIVIVICMLLFALMIRIILGLA
                     ESLAGQLNFQYIASELIYILVLVEIYRLLIIYLREHRIAVDIMIEVGIVSILREIILH
                     GVLGINALSIMALSFFLVALMLLLRYGAIRKEEVEGVPRDGFLTELKRTLKRETRD"
     gene            20856..21629
                     /locus_tag="PK679_00105"
     CDS             20856..21629
                     /locus_tag="PK679_00105"
                     /EC_number="6.3.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HPC54398.1"
                     /translation="MHIEVEGVAGLPMIRKGDDLAALIAGRVSFSDGDILCIASSVYS
                     KAKGYTRCLRDIVPSERAERIAGKTGEDPRFIQAVLDASTDVLLEYPFVLSEVACGHV
                     GVRAGVDQSNIEDDMVILLPPDPMAAAREIREALRELTGKSVGVIITDTCGRSFRRGQ
                     TGHAIGWSGMTAIRDFRGDTDLFGHVLKITEEAVVDEIAGFANFVMGESNNGVPAVVF
                     RNCGTWQGHDNLYFNADEDITRALLKGAHRGSTPPRKER"
     gene            complement(21666..21845)
                     /locus_tag="PK679_00110"
     CDS             complement(21666..21845)
                     /locus_tag="PK679_00110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54399.1"
                     /translation="MVSTVVLINGLQAAGGAGLIILGAMELVGNPGFIDYFALVFGTF
                     FFAVGIFGLVRGKTA"
     gene            complement(21887..22510)
                     /locus_tag="PK679_00115"
     CDS             complement(21887..22510)
                     /locus_tag="PK679_00115"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: protein motif:HMM:TIGR00758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HPC54400.1"
                     /translation="MDDGPGVSPAASMDRLAARIAACTLCPLSLSRTRTVPGEGPVPS
                     PLVFIGEAPGKTEDETGRPFVGRAGTILTGLLADCGLLRGEVFITSIVKCRPPGNRAP
                     KRDEIAACMPYLKAQIALLSPRVLVPMGRSATMTLFDLYGIPFPSFREVRGHAHAVRD
                     DRSGRGMTIIPVYHPAVITHNPPARQDLESDFRKLAAFIRSSPGDRK"
     gene            22553..23476
                     /locus_tag="PK679_00120"
     CDS             22553..23476
                     /locus_tag="PK679_00120"
                     /inference="COORDINATES: protein motif:HMM:NF014527.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmD family RNA methyltransferase"
                     /protein_id="HPC54401.1"
                     /translation="MRFLPPGIRAGRTGTREGRGIDRLPKTRGDAKRARGLTMGWRKH
                     VSPGLPPDLARRLPSGYEVIGDIAVISLPDELRDYAHSIASAILARHGNVRTVLDRRP
                     IPRGDTRVPEVRVIAGTGTTTTCREFGYSYRLDLARVFYSSRLASERQRIAGLVRPGE
                     EVLVPFAGVGPFVVPIAARGARVTAIENNPASVGFLRENLRRNRVAARVTVIEGDFYE
                     AARSLPPGFDRAVIPAPYRRDDALPVGAGLVKEGGRIHMYTFGRIGAEDELPGKYEGM
                     GFGITRVRRCGNVAPGICRYALDLVRMPHPA"
     gene            23572..24546
                     /locus_tag="PK679_00125"
     CDS             23572..24546
                     /locus_tag="PK679_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="slipin family protein"
                     /protein_id="HPC54402.1"
                     /translation="MKQPNNLQVAVFLVLFAIGVSAAYSLYTATGEPASLVTGLAALL
                     VALFAAAAIQVANQWEKAVVLHLGRYKGLFGPGVFTIVPLVETVAYWIDTRIITTSFT
                     AEKTLTKDTVPVDVEAVLFWRVVDPERAALLVEDYRAAVSWAAQTALREVIGRSLLAE
                     MLEGREKLDLELQRIIEERAEQWGIHVSSVEIRDVLIPAELQDAMSMQAQAERERQAR
                     VILGDSERQVAEKFEEAARTYQNNPTALHLRAMNMLYEGLKEKATLVIVPSTVLDTMT
                     LGDTSGVIALSRTLGGQQQPAAGEGMKREKEKEKEAPKPAGEPAGGAL"
     gene            complement(24578..25030)
                     /locus_tag="PK679_00130"
     CDS             complement(24578..25030)
                     /locus_tag="PK679_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5814 domain-containing protein"
                     /protein_id="HPC54403.1"
                     /translation="MIAAKARFRHARRLERLAGFRIPDQAFHGATLEAISSHLNFDRL
                     DHTLHDQIVRFVHAFLRCNCRESPLCGCPERKFSREILELRENGLDHRQISQYLLEEY
                     GIDVYPADILSFLEDSVHVLEAVEDIARLGNIPLLADAAADHIGKLER"
     gene            complement(25027..25659)
                     /locus_tag="PK679_00135"
     CDS             complement(25027..25659)
                     /locus_tag="PK679_00135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2150 family protein"
                     /protein_id="HPC54404.1"
                     /translation="MAKKKEKAASQEEPLKLFYIFYNQERWDNWIKTLRESRFEAEPG
                     SDEMPEGYTVLYNFAMDVTLSVLKIIKLYQNGRYTKEEALEKLNEVEAIVMGEAPQDE
                     LEDYVESLQLSLLVLFAACRKFLSGEYGKDIKALVSEGRKAIGDDMEKALDKAAEVGA
                     NVIGGASCCGRYIRDDLDQPTLFDEWLIEIESMAEAVSSLKNFDEEAGEV"
     gene            complement(25794..26660)
                     /locus_tag="PK679_00140"
     CDS             complement(25794..26660)
                     /locus_tag="PK679_00140"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HPC54405.1"
                     /translation="MYEKVLVPFDFSPGSKHAVECVKSIPGTRHVLLLHVVYTKTPSV
                     AGEFVNPDADYARLRLEEYVRSLGNPGFAIATRVEEITGGNISDVVNRVAAAEGISLT
                     VMGRRGQGVIEALLLGSVASDVLRYGTTDLLLVGRPGKEPAGGAKPPCPDLFSHVVIC
                     TDFSAPDVVALACGRLPRPRRVSLLHVVSHGESEDEVRKLTESAWAELEECTGAFSSR
                     HVPVETAVRVGSTAEEIVAFSEKEGATLIVMKSAGKRGFIPGFPGTTTAHVARAARVP
                     VLVLKQPAVAPQ"
     gene            26898..28097
                     /gene="thiI"
                     /locus_tag="PK679_00145"
     CDS             26898..28097
                     /gene="thiI"
                     /locus_tag="PK679_00145"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA U4 sulfurtransferase
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HPC54406.1"
                     /translation="MTVLPPGPAVMLRYGEVFLKSDPVRREFTNTLVRNCREALRSEG
                     LSPAERITRGRIFFCGEPAGRVAAVLSRIFGVVDVAECTLTPPDPGAVTEAAVARARA
                     SAGPAKTFAVRARREGDFGMTSRELAARVGSAVLAACPGITVDLDNPDYELHVELRQT
                     GGVVYDRRIPAPGGLPLGTQGRVLALLSPGIDSPVAAWLMMKRGCEIVALHVSHGDGE
                     DPSTLPGTLRNLAILSGWCRGFPLRLFVADAGPFYEKLAGLHNQRFTCVLCKRFMLRL
                     GTLLARREGIAALCTGDNLGQVASQTLANMVVISNAAGIPVFRPLITFDKQEIVTLAR
                     KIGTFDERPGDLSCPFVPGVPATTSREDEIRTLEESLGTDALLPGILGNALEYVACNG
                     GVTRRSP"
     gene            complement(28094..29371)
                     /locus_tag="PK679_00150"
     CDS             complement(28094..29371)
                     /locus_tag="PK679_00150"
                     /inference="COORDINATES: protein motif:HMM:NF012415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HPC54407.1"
                     /translation="MGIRFFRGEKIKLEHEFRQLREIVRILREEYAQEPVYILTGVLV
                     ANGQIDCIILTRNGPVLLDLKAFRGEIRGLENGNWEVGTKDGPIPLPNLFLQAKIHRQ
                     DFIDRMIPVCREHFPHVGEQNLRRTASWLYFCRGSTYPAGQIDFRKVKWFRVVTADDL
                     LEKLRFVDSGYTLRIQDMDAIVRGFHLEEYSFEKESPLIPAAREERRPLLSRRALTAL
                     VVILAAFLVAVLILALVPGARIAAGNAVQGILAVAGGWVQSLAGGALKTNTTVDESRQ
                     AVLHLNRIRAAEGKPPILFDERAYALALARARDMEQYGYLDYTNPRTGSSALALKRSY
                     GFSLNDTLIETLYGQWTSYVPGIETQAIDSWMMDAGNRQRLFFNQTSGAIACSRGYCS
                     YIGVRYAPQEVAAGQPSGNITANLSAQPQTLPG"
     gene            29516..30568
                     /locus_tag="PK679_00155"
     CDS             29516..30568
                     /locus_tag="PK679_00155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HPC54408.1"
                     /translation="MAERRRARFGGWERVTIRDDAGRMREAIAPVIVSASRSTDIPAF
                     YGDWFIRRLEAGHAAWVNPWNGRSTYVSFAKTRAIVFWSKNPRPLLRHLPRLDALGYS
                     YSFLYTLNDYRQENLEPNLPPLAERERTFIDLSSRLGPRRVSWRYDPLLLSDALSVDD
                     LLSRIESIGSRLHRYTRRLIISFVDIARYPKVRSRLAAGGHPGVREFSETEIDAFCSG
                     LSDIAAGWDLEVSACGERRDLSQYGIRPGQCISAARMREAFPGDETLLSFLAPPPGTS
                     GVTGEAFLRDPGQRKECGCIASKDIGRYATCMHLCAYCYANATEATVVKNWTRHRRMM
                     ESGIVPESIAGTGEEI"
     gene            30591..31109
                     /locus_tag="PK679_00160"
     CDS             30591..31109
                     /locus_tag="PK679_00160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54409.1"
                     /translation="MPRRDPLTPEQKWLAVTRFATALPVLYDVTFRERIGDEYDRLDQ
                     QIWVRLATVARDFATSSGLPAGNAGELMETLGALLLALFGPEFRMENVPLDEGRAVLM
                     IKRCPFAFREAEVRGGPENLLPRCLAFSIATVEALNPAFTLRFVRSMCMGDRTCELKV
                     MRREDAERDDAR"
     gene            complement(31168..32568)
                     /locus_tag="PK679_00165"
     CDS             complement(31168..32568)
                     /locus_tag="PK679_00165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HPC54410.1"
                     /translation="MCHGLKDARLAGPGIRRVILFIAIVSSFITPFDGSAVNIALPAI
                     GEEFSLDAVTLSWITTSYLLTISVFLVPFGKLADIRGRKRVFLAGITLFSCASLLVSF
                     STGAFWLIAFRLLQGAGCAMIFGTSLAILSSVYPPGERGKALGITIAAVYVGLSLGPF
                     LGGIMTETLGWRSIFLVNVPLGIACVFLTLRKVPAEWREAAGERFDYAGSLLWGASLV
                     SLIYGLSLLPGTAGIILVLLGVAFLLAFAAFELRVPFPVLSMQLFLANRVFAFSNLAA
                     LINYSATYAVTFLLSLYLQVARDLPADYAGLILVAQPVTQALFSPLAGRLSDRVDPGR
                     VATLGMVFVVTGLFFLGFLGRDTPIPHIIACLVILGTGFGIFSSPNTNAIFGSVEKRL
                     YGVASGMVGTMRLLGQMFSMGIALTIFALFIGRQELKDAEPSLFIGSLDTAFFVFFCL
                     CCLGIAFSLVRSKRTA"
     gene            32716..33399
                     /locus_tag="PK679_00170"
     CDS             32716..33399
                     /locus_tag="PK679_00170"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HPC54411.1"
                     /translation="MKVGVLCSGGKDSLFACMCAMQEEEVACLITVFPDNPESYMFHT
                     PNLHVVRLQARAAGIPLVAGTSRGREEEELADLSRTVAEAVERHGIEGVVTGALQSVY
                     QASRVQAICRDLDLWCFNPLWYADPGEYMETLVSSGFDVIVSAVASEPFDRTWLGRRL
                     DRAALQDLRRYAERYGTSLPGEGGEYETLVLDAPFFRHRIVIGEAEAVWQNFRGVFHV
                     KEAWLEGDA"
     gene            33396..34010
                     /locus_tag="PK679_00175"
     CDS             33396..34010
                     /locus_tag="PK679_00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314162.1"
                     /note="Members of this family of hydrolases with an active
                     site Cys residue belong to MEROPS family C26; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HPC54412.1"
                     /translation="MILLAGLGFRDAALLRSEFVRPVARVAGHWGAEWSYCHYSRLPD
                     DPADGYDAVILCGTALKDTGYLREIGRFSWLIEAPVPVLGICAGMQVLSLVHGGTLRP
                     ACEIGMVDVRVLCPNPVLPPLPSFQAYALHRYSCDPPPGWTTLAVSETCVQAVSHPHL
                     PLFGVLFHPEVRNGVVIERFLSLVYHGKEGEGEEGQDAPPSGHG"
     gene            complement(33996..35174)
                     /gene="pscS"
                     /locus_tag="PK679_00180"
     CDS             complement(33996..35174)
                     /gene="pscS"
                     /locus_tag="PK679_00180"
                     /EC_number="2.5.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-phospho-L-seryl-tRNA:Cys-tRNA synthase"
                     /protein_id="HPC54413.1"
                     /translation="MKCAGDIEVRAVEEESINIDPIQAGGRLTAAAMKALIAYGDGYS
                     VCDNCRKPNRLDYIKKPPIDRFHRELAEFVGMDVARVVPGARRGFQAVADTYVEKGDP
                     VLVTALSHYTEILAIEARGGIPMEIPASPDNIITPDAAAAKIEEVIAKTGRTPPLLFL
                     DHVDYSYGNLHPVREIAKTAHGYDIPVLLNGAYTVGIMPVDGKDLGVDFVVGSGHKSM
                     AAPAPSGVLAVRNERAGEVFRTTAARTDVTSRTFGIKEVEMMGCTLMGATLVGMMASF
                     PEVRERVLRWDSELANTALVVDALKRIGGTAILSQYPRRHTLTRVDTSQSFDRVAEKH
                     KKKGFFFTSALKDRGITGIIPGATRVWKFNCYGLSRAQAEYVAESFIAIARENGLPVS
                     "
     gene            complement(35171..35353)
                     /locus_tag="PK679_00185"
     CDS             complement(35171..35353)
                     /locus_tag="PK679_00185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54414.1"
                     /translation="MSKAAIVALFEAMFILSDIRVILRKTAPHHRLGPGEREEVESLI
                     AGLEKQVGVLKRELLP"
     gene            35472..36620
                     /locus_tag="PK679_00190"
     CDS             35472..36620
                     /locus_tag="PK679_00190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HPC54415.1"
                     /translation="MKLVHIADTHLGLAQFQKVDPDTGMNLREKLIYTNFLAAIDRII
                     SLRPDVVVHAGDLFDQVRPKTMAYTTALEALERLSEAGIPLVLISGNHSMPKTRYTPS
                     PFRVLEFHPGTLHAAYSYRYERVEIGEAVFHLVPNMLRPEHYREAYDRITPDQNRFNV
                     LVTHGLASALKEKRLNTVAEHEIDATMVSGGGMFDYIALGHFHGQVQVGERAWYSGSS
                     EYITYGEIGDIKGGLCVDLGRGIVDHVPLPHTPMADLGTIDAREVPPRDVPGLIRQRL
                     EVNRVGPLSMAGVTLCFSDREHQRQLDEKELAGVRRELLDLKIRISVPGEYRKGGETR
                     DIRSIDYLGEFSRFVAGKNLAQGERDFIAEYGSRAISLALEEEGPGAD"
     gene            36610..39315
                     /locus_tag="PK679_00195"
     CDS             36610..39315
                     /locus_tag="PK679_00195"
                     /inference="COORDINATES: protein motif:HMM:NF014516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HPC54416.1"
                     /translation="MLIERLVLRNFKRFGDAEIRFRDGITGIVGNNGTGKSSIVEAIL
                     FALFGVQGTGVQSDYIVSSFAGEKAKCEVRLDFQVQGVRYTITRAFRKGGQTVHEARL
                     HMGERLLASGVSEVAAEVERLCGMGPSDFRNTVYAAQKDLPALLESRPGARKEWFMQA
                     LGIEKLKARSDEAVREWIDEAERAVEREKNRLAVLSGQGDVSEIPVLAEELGRIGQEI
                     AGKEAERQRLEEVSAILARAASLVQSDAALEARQKQAESDLLRLATAADRLAELAPAV
                     RRFGELEEELTRQKEKEQRFAELRDRMGRAEAAVRAGKKRLLDLSEQIDVYSAEAPEL
                     EGLKDVPDRLAEARKTVANLDKASFIWQSLSDLSSLAERIARDLAGCEEDERALLAEL
                     AELEGLREKRRELEELAKSRSRASAECALRAEALAQERAALSADWERIRSSGREGTCP
                     LCHQTLGEFFPRIEQEYSGRFSRIDEELDSLSRTLEACRGEEERIGKELAAVDRALEQ
                     LSRVGQALQETRAKKKGLSDRLEEIGRDREARYGELSLLGITAYSPEAHAQARESVRL
                     LEVQVQRLQELRFHQERLAALTRERDRLLDEMEREMADLRSLGAEIAALDYDPALLKA
                     GEEEYRSLRPARDEAIALRERLAREPEIRREMDRIREEREQIRELLSSCRENLARLGF
                     PEADSASVSARLQELAQEISRLNTRQGSLQEQHARLLSIAAEMEKAQKELAALEKRLV
                     LLRITRKTVAEFVLYLAGVIRADIEDEVSRILSGITSGRYDRVIVDEDFSVLVQDIDG
                     DFPVQRYSGGEQDDIAVALRIALSRCLSGLHGVSENMFLVFDEIFGSQDEERRANLLQ
                     ALRSQEAHFPQIILISHIPEIQGEFAHTLLVEMADDQKSRIVEVS"
     gene            39316..40341
                     /locus_tag="PK679_00200"
     CDS             39316..40341
                     /locus_tag="PK679_00200"
                     /inference="COORDINATES: protein motif:HMM:NF020933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA double-strand break repair nuclease NurA"
                     /protein_id="HPC54417.1"
                     /translation="MQGDAYRESIRRVAHAVRDCLPRDIGRLFAEHSGMTRGDFFPLT
                     PRRDGIIRAVDGSNATVMEAGNMAVVAARAGFSSFSGEKRLPGGLTPVLLLQAGPRDA
                     EREFSHQYGECFGFPPRSPLRVDDTSRAAAAMRDTLEYWVASVCAGHQERGGLLLLDG
                     ALRVSEESHDPVLVGIIRECQSRGVGLAAVSKRTAATWGERYPLLPAVRALSRDLGVS
                     SPWWVRIDEEILDRTRYSQWEHGDIFVCSLARGNALPLKAELPRGCDDVTAHAIFSLL
                     SGCSDDARAEGYPYPLLDAHRNVVITADLLEQIRSDLLSGFAEEGLLARDIGELFGDY
                     HDTFRRY"
     gene            40319..41941
                     /locus_tag="PK679_00205"
     CDS             40319..41941
                     /locus_tag="PK679_00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC54418.1"
                     /translation="MIRLDDTETQDRSKWRLIGTSVLSYRFIVPHDETVFVGDIIKIE
                     DVSKGLVFFARVTDLIHESNFADEKWDTRPYTGRFYTLGEDVFLGVEAVPLGYVDTAG
                     KFRKPRTIPTKFSPVGVPTEDDLSFLSTVMGDIEVGVMRTGQDVLRGVPVRIHSSVLP
                     QHMGVFATTGMGKSNFMKVFCASCMQARQFGLLIVDPHGEYLAGGRSSTGEPTKGLIH
                     VPGLRDGLSVFTTRSEEQRRQYSASSLSLEYDDIRMGDLSALYDLSDPQRDILEALGD
                     YRGSTVIGFFSRLDPEEFTPATYQSLQGPDRDIAFRLRTSNPGPLRVIKRRLENLVKG
                     NRKFFREKGSCIPDILAALMERKVVLVDIPGMSERSELFVLSVLTRVILEHQKEQAER
                     YDSSEGTSPALQPILITIEEAQRVLGAGGQSTQVFRECAMEGRKFGAGLCVITQQPKN
                     IDPKVLAQINTFVIMGLGDRGDRETIAGSAKQDLSRMDTEIQTLERGEAIISSFSIPF
                     PVSTRIHRFEDYITQIPAKRRTPLSEGLDTTF"
     gene            complement(41953..42489)
                     /locus_tag="PK679_00210"
     CDS             complement(41953..42489)
                     /locus_tag="PK679_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding protein"
                     /protein_id="HPC54419.1"
                     /translation="MKIGEVNAKVSILALVVVGIFSILLIYTYLVTGDQVYLVWGIPT
                     VILLLVIPLALNYMSQSEYANLEPMYRDKARPVRIKMINPHMLGEIVRIEGVVERVYF
                     QFINRPQYLVADRSGEISVKMFTTPRYRVKKGDVVEVFGQVMKRYVVTGDPVVNAVSI
                     SPVEKTVSARREKKDSGS"
     gene            complement(42499..43377)
                     /locus_tag="PK679_00215"
     CDS             complement(42499..43377)
                     /locus_tag="PK679_00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HPC54420.1"
                     /translation="MVFHPPVAIVAKAGDAGKYKVGLPAWNMIMRGFMSGAYIAMGGG
                     LATVCSTGILATDAALRYGTASAGFAQLITGAVFPVGLIITVLTGAELFTGDAMLAPM
                     AAFIHKVSWAQVINLWVWVYIGNLIGSIVYAYIMANGPFVTFDAAGAATVTAFGSRAI
                     AIASAKVSYVGTMGMWSAFLKAIGCNWLVNLAILLGICADDAVGKFFGIWFPIMCFVS
                     TGFEHSIANQYFISAGILTQGFITDPAKINAGLNWVTFWTNNMIIVTIGNIVGGMFFV
                     GVIYWVAFRKEIAALK"
     gene            complement(43579..>43754)
                     /locus_tag="PK679_00220"
     CDS             complement(43579..>43754)
                     /locus_tag="PK679_00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HPC54421.1"
                     /translation="FSLHRYMKCGVGVCGSCCIDPGGLRVCRDGPVFSGDILAGGEFG
                     RYSRDAAGRRRPV"
     assembly_gap    43755..43854
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<43855..44498)
                     /locus_tag="PK679_00225"
     CDS             complement(<43855..44498)
                     /locus_tag="PK679_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HPC54422.1"
                     /translation="MSDGLPVPVRITRVVRETPSVATFAFDRVFSFVPGQFVMVWVPG
                     VDEVPMALSSPSSITVQRVGDATAALFRLGPGDSIGIRGPFGNGFPQKRRMLAVAGGV
                     GAAPILPAVVAGGVDKVLLGARSAGELLFRERFESLADLSVATDDGTLGFHGFVPDLL
                     GNEDVSSYDAILVCGPERMMAAVLGILSGRGCPEKGYFSLHRYMKCGVGVCGSC"
     gene            complement(44491..45378)
                     /locus_tag="PK679_00230"
     CDS             complement(44491..45378)
                     /locus_tag="PK679_00230"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HPC54423.1"
                     /translation="MLTLRPGPVSAGGVTLKNHLVLAAGILGTTGASLSRILGSGAGG
                     VVTKSIGPVPLGGHPGPCLVSLDCGLLNAMGLPNPSMEFLDELAPLAGRPVIASIFGG
                     SPEECATVSRWFRGKVAGVELNLSCPHARGYGAALGTDPVLVEECTRAVASAGLPTWV
                     KLTPNVTDIREIGMAAERGGASAIVAINTLKAMRISVGLRRPVLGNRYGGLSGKAIFP
                     VAVRCVYELYEACSLPIIGCGGVSSAADVLEMMMAGAVAVEIGSAVMEDISIFSRIGS
                     ELYAPDGIPPEEIVGCAHE"
     gene            45441..46307
                     /locus_tag="PK679_00235"
     CDS             45441..46307
                     /locus_tag="PK679_00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HPC54424.1"
                     /translation="MARISVLGTGRIGGEVAYLCAVLGLADELVMYDAVAGFLRAQVL
                     DLLHTGLDVPVSTSWKDAAGTDICIFSAGIPRTPAVRTRADLMHANLPVASECSQAIR
                     RFSGILITVTNPMDVNNYYLCRKNGLEPGRCIGFGGQVDSARFGLLLRERGISGRPFV
                     IGDHGENLVPLFSHLDDTVDIPVREEILGRLRGSSMEIIQGKGGTVFGPAYHIAMLIR
                     TILKDERKVLPCSCIPDGEYGVRGCSIGLPAVIGREGIHRIEEWPLDPWEQEKFAAAQ
                     DAVTGLCRELGV"
     gene            46316..48787
                     /locus_tag="PK679_00240"
     CDS             46316..48787
                     /locus_tag="PK679_00240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed DNA polymerase"
                     /protein_id="HPC54425.1"
                     /translation="MELSGKTAGVEKGGNGRPGEEGGLLVSVMQIEYTVGPSGPVIHV
                     FGRDRTKEAVHVQVTGFRPYFYVPAELAAAAPPSPRAEVEAGKKYTSIRGEELVRIYT
                     QKPTDVREERERYRAHFEADIPFTTRFAIDCGIRGGLFSPSPIADYREVSPADADVPP
                     RICMVDIECEDVRGFPQPARDAIVCITAWDSYEDKYSTFLFAPPGTPPDTGWLAKVSP
                     RPSGCFDPARHEVAVFPDEKGMLQAFAAYIRKTDPDILSGWNFAEFDLPYLSRRMEVL
                     SLPFSALSRLEGQTERLAVRGRAQFDLLLAYRKMHATQKESYRLDAVAEAELGDTKVR
                     YRGTLSDLWTSDPALLVEYNFKDVALCVGINGKNRIIEFYREIARYVGCPLEKTLNSS
                     NVIDIFVLRKAFGRYVLPSKGYAPAEEFEGATVFDPSRGIRENVVVLDLKSLYPMAMM
                     TINASPETKDPRGELRAPNGVRFRKEPDGLTRSIIRDLLAERDEKKAMRNRYPIGSPE
                     YTVYDMQQNVIKVIMNTYYGVSGYARFRLYDREIGAAVTSVGRAIIEHTRRVIEGLGY
                     RVIYGDTDSCMVELPGLDLPATIAESRRIEAVLNASYGEFAKRELNADVHYFSIKFEK
                     VYRRFFQAGRKKRYAGHLVWKEGSIVDGIDIVGFEIRRSDYPQITKAVQARVIELILR
                     GEGYDAVRKYLGEVIRDFRAGKFPLDEIGIPGGIGKELGEYQNDDAHVRGARYANDYL
                     GMDFSRGSKPKRVYIRNVTGKYPKTDVLCFEYGDQVPPEFQVDWEVMMEKTIKQPISR
                     IIEALGWSWSDIDPSRTTLAQWGIG"
     gene            48784..50166
                     /locus_tag="PK679_00245"
     CDS             48784..50166
                     /locus_tag="PK679_00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042242 - cobyrinic acid a,c-diamide
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HPC54426.1"
                     /translation="MTARSGPPDGGGGPGGVRVTIPRVVIAGTHSGCGKTTVARGIME
                     ALVARGYTVQPFKVGPDFIDPTHHSAVCGRVSRNLDPFMMGEDGVRETFARACRGADI
                     AVIEGVMGMFDGLDGTDCASTAHVSRILSSPCILVADVHGMSRSVHALLLGYATFDPA
                     VRVAGVIFNRVGSDRHRTIISSGLQVTSLGYIPRHPGLRVESRHLGLWMAHETGSDGT
                     WGRIIEEHCDIGGIVRVAGDAPPIPIAGPVERHFPPPSVRIGVAMDPAFCFYYQENLD
                     LLRAAGADLVFFSPLNDPLPQVDAVYLGGGYPELHAEALSRAACTAALRKAASDGMPV
                     LGECGGLLYLCESLGVERTFPMAGILPATAEMTGKLQALDYVSGMWSGGPPLAPSGSP
                     LRGHEFHYSAVSCGSDARFALRLSRGRGISGGMDGLYEHGSVGTYAHSSFSPAFAGSF
                     VRAARDWQRA"
     gene            50328..51980
                     /gene="ilvD"
                     /locus_tag="PK679_00250"
     CDS             50328..51980
                     /gene="ilvD"
                     /locus_tag="PK679_00250"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HPC54427.1"
                     /translation="MRSRKVKEGYQRAPNRSLLRSLGVTDREMDLPFIGIANAWNDIV
                     PGHVHLRMLATKVREGITAAGGVPFEFGVIGICDGIAMGHEGMRYSLPSRENIADSIE
                     LMVESHALDGIVLLGTCDKIVPGMLMAAARCNVPAIAVTGGPMLPGFLEGRNLSLIDV
                     FEGVGRVAAGTMSADDLHALECAAMPGCGSCQGLYTANTMACMTEAMGMSLPGCAAAP
                     AVDAAKLRIARMSGERAVGLVREGRLPRTIITRESLQNAIRVDMALGGSTNTVLHLMA
                     IASEADVDLSLESFRKIGEEVPHICNMQPSGPHSMLDLYRSGGIPAVLHELAGYLEDA
                     PTVSGRSIIEIAREARPWKGGIIRPVKDPVNPAGGLRILFGSLAPGGAVIKSAAVAKE
                     MWTHTGPARVFDGEDAAMKAILSRQIREGDVIVIRNEGPAGAPGMPEMLSPTSAIVGL
                     GYRSVALVTDGRFSGGTRGPCIGHVTPEAAVGGPIGLVREGDRIAIDLHARTLDLLVD
                     PKELERRRGEWKPPQKPLRGVLARYAEMVGQADRGAVLRKEK"
     gene            52015..52212
                     /locus_tag="PK679_00255"
     CDS             52015..52212
                     /locus_tag="PK679_00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54428.1"
                     /translation="MTEKTTSKYERVLCTHCEGAGCIYCEKTGYVLVLAPARRCRHCD
                     GDGCIYCGFTGWAGLKGRYDE"
     gene            complement(52404..53042)
                     /locus_tag="PK679_00260"
     CDS             complement(52404..53042)
                     /locus_tag="PK679_00260"
                     /inference="COORDINATES: protein motif:HMM:NF018028.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HPC54429.1"
                     /translation="MLCPKCGRETESDGRFCQWCGGDLRVAPPRAVLRKRVGEITTAK
                     YASLPRRIGAGFLDIVFLLFLDILVAGLVTILSWIAQKPSPLSEAIVMLYQYYLHLPR
                     TDAYGNVVRALVPTQVIIFFGLFLLVVPWLYFAYLESSSNQATLGKMVMRIAVTDMRG
                     NRITFARASLRFLCIFLSVLTIFVGFLIPAFTRYKQGLHDIIAGTLMFLQEY"
     gene            complement(53185..54264)
                     /locus_tag="PK679_00265"
     CDS             complement(53185..54264)
                     /locus_tag="PK679_00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC54430.1"
                     /translation="MKTRNILLIMKKDLGSLAHERTILLAILLQLFVALFSSFLMVGL
                     TSMYDPSALARFEGVRYPVGYVGEQGDLTRLLRESRQFVVYPMDLSTAVAALKERKLA
                     AVLYVPPTPPDAEEPVKITLYTLQNDIQSTIVNVKLKEVFLAYEEALRMLRAERLDVI
                     PEKLEFPDAGPGPGFYEFIYGLLIPLLLFMPAIVSAALVIDLICEEYQHHTLETLLST
                     PMTMTEVVWGKVAACLVLVPLQAGTWLALLSLNRIAIANIPQIILHVVSVSLALILLA
                     AIVSLFYRERTSAQFIFSTGVVVIMLAALSFPGNPLNTIAQLATGTETPLQHAVLGLS
                     AGACLVLALAMQAFARRVPARGPGE"
     gene            complement(54265..56079)
                     /locus_tag="PK679_00270"
     CDS             complement(54265..56079)
                     /locus_tag="PK679_00270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HPC54431.1"
                     /translation="MDVRVFLSHVATMARWEVKRTFGVMGKNTLPVAIVLVLCLVATT
                     GLTAERGLHIQDGIYRLGTDNPAVAGILGGDARFVVSYGDAPALFSNRGSLDIIIAGT
                     DVYVHDSERGRSALRTLQRDYQHYLDSVYSAQQDLFAAYPLWIDVQEIRSELDFSATQ
                     SGRQISAVATPRQPPVPEKPVEQVPTPEPGIPIPPGEIRQGLLQSREQPGEIARYSDL
                     LGSESPFGSFRIPSQLSPPLPFDSIILVFLFIFPLYFSSQFYMMSIMQERIERRGEVL
                     LSSPAGGAAIVVGKALPYLAGMLAISTGIALYIRAPLTILLPLVPVILFFLASALVIG
                     MVSRSFKELSFISIFFSTVATSYLFFPSIFANVHVISIVSPLTLIVLSLQGDTYTVTQ
                     YIYSTSLFFLTSVILFYVGIVNFREERLFSLSGIVARIREFVSAALSARHPYLSVFAV
                     SALLVPFVFMVQMLLLVLVFNLPMPLSLVILIVTAACVEEVAKSVGIATFILEGGSGV
                     SWTFVALGSLATAAGFLFAEKLLLFVTLAQITESIFGSILFLTLGSLAYPFLLHFACV
                     LVLSVFVRVLGRKGYLPGLGLATLIHCLYNATIILGWI"
     gene            56162..57049
                     /locus_tag="PK679_00275"
     CDS             56162..57049
                     /locus_tag="PK679_00275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC54432.1"
                     /translation="MITARDLSKVYGKTTVLRNISFDLDEGRILGIIGHNGAGKTTLL
                     KILAGLIEPSGGQLAINGKNALNNPDGIRQVIGYLPEESRLYETMRVNEYLTFFGEIY
                     GMDRSSIRARSRDLLDWLALEDNGKKIGEFSKGMKRKAAIARSLIHDPSILIYDEATS
                     GLDPMTSRHIIDLLRDLRSRKKTIVLSAHNLYQVEAICDQILILRRGERVALGTISEL
                     REMFGSVYYTVFFTIGDPERIRGIGDFSRDGGYFRVNAPSVGEMNRITQEIASAGGAV
                     ERVESHYPSLEEMLVKIGA"
     gene            complement(57452..57525)
                     /locus_tag="PK679_00280"
     tRNA            complement(57452..57525)
                     /locus_tag="PK679_00280"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(57489..57491),aa:Lys,seq:ctt)
     gene            57675..59138
                     /locus_tag="PK679_00285"
     CDS             57675..59138
                     /locus_tag="PK679_00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HPC54433.1"
                     /translation="MPRAGESGTGGNVRYAVLGCGTTGYHVALELAARKESVLVCDID
                     ESRVRELREQKFDAVRRDISDPGFLAGLPSFDVAFVLSGNNQVNTTAVRTLRQALPGT
                     HIIARATDPLGAGQLGSAGADLVLYPQQVVARAAIHQADKAHAGGLARKLHSLLAGWE
                     GTLAIVTHNNPDPDAIGSAMALAAIAKSANPQKLKCRIFYDGIIGHQENRTMVNLLDI
                     RMEKLDPEAIQDCSYIALVDSPGPGMNNSLSPRTRVSIIIDHHKDGHGQDSAAFSDIR
                     PGMGATASIISQYLQELDIPVDKNVATGLFYGIRSDTREFRRNVTPQDLANAAFLLPL
                     TDGDILDQIMSPSLSQETLDVLGNAIKNRHIQSGYLFSNVGYVHNRDSLPQAADLLIS
                     LEGVNTALVYGITDDAIVISARNRDIRLHIGNVLEEAFGDIGDAGGHPNMAAATIPLS
                     YFRRVRNKEGLLALVMDPLIRRFMGLVGLEAEEGHEV"
     gene            59128..59742
                     /locus_tag="PK679_00290"
     CDS             59128..59742
                     /locus_tag="PK679_00290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF115 domain-containing protein"
                     /protein_id="HPC54434.1"
                     /translation="MKFEEWEPVYREIVEYFGFDRKEDERAAEILAGLLDRDDLPLLA
                     RLIAGKDVCVCGNAPALSREISLVTGCVLAADAAALVLYAHGIRPDAIFTDLDGAQDE
                     FIDMNREGTIIVVHAHGDNIPLLRSWVPRFPGPVVGTTQSRPLPRVHNFGGFTDGDRA
                     VFAAQALGASGITLRGFDLDDTRVDRMKRAKLAWARRLLRQILP"
     gene            59739..61391
                     /locus_tag="PK679_00295"
     CDS             59739..61391
                     /locus_tag="PK679_00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC54435.1"
                     /translation="MKKKTAFILDGYVDEPACLGVPPFISPSIRTLAGVLTEREFETG
                     YLTIDQVRQDPATLRVLNESSLVVMVAGVTVPGKYMGGTPATLTEIHQIGAALSLPEK
                     VLAGPIAFGYSPGGGRKAEKGAVPGFDAVLSGSPASALDRYLSGKEPSGSFDYKREDP
                     WSVSGAGIIRKHPRFPLVMCELETARGCTRFHSGGCSFCTEPFYGPPVFRTVDAIARE
                     VDALSRAGARHFRLGRQPDLLVYGASPASEFPSPVPEKIEELFSCVRRAAPTLATLHI
                     DNVNPGTIARHPDESRAALDAIVSCHTPGDVAAFGMETADPVVIERNNLKAQPDEVFL
                     AIRIVNEAGGHREEGIPHLLPGLNFVAGLAGETARTYSENLRFLDRVLASGLLVRRVN
                     IRQLMPFEGTRAYTENTLGAHKSLFASFKARVREKFDLPMLQRVFPVGTILRNLVIEE
                     EGIPSFGRQMGSYPILAGIPLRLPLLTVLDAVVVDHGMRSVTALPVPIAINTLPARAL
                     SWIPGVGKQRAARIAGARPFRDIGELRAVAGPLPLDHLFSFS"
     gene            complement(61388..62521)
                     /locus_tag="PK679_00300"
     CDS             complement(61388..62521)
                     /locus_tag="PK679_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54436.1"
                     /translation="MNGSFKIGSIFGIPILIHWTFLIIIPVFAWIIGTQILLTVDLLS
                     NTFGVPIDTTYLLPGLNPYILGAFVALGLFAGVLLHEIAHCIVAKRKGVPIHSITLLV
                     FGGVSSMEDSAPDPRVELPMALVGPLTSLATGLLFIALMYAVTLAGFAGPLSGLLVFA
                     FSYLGLLNVFLFAFNLLPAFPMDGGRVLRAYLATRMPLPDATRIAADVGKAFAVIFGI
                     VGVLLFSPILILIAFFIYIGATQESAAIRYTFLLKDVSVGDIMSSPVMTVPPQTPVRE
                     VIDLMYATKHLGFPVVERGHLAGMVTLADLHRVSPIDREAMQVRDVMTRDIITLPPSA
                     PVIDALRTMSAKNIGRIPVTVDDQLVGIVTKTDILKVIELREI"
     gene            62571..62843
                     /locus_tag="PK679_00305"
     CDS             62571..62843
                     /locus_tag="PK679_00305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HPC54437.1"
                     /translation="MRTQITELFGLNIYTEKSVFVGEVEDVILDIEGKKMESLVVGKL
                     NQDLVDIKNYKGLKIPFRIIRSIGDIVIIRHLPGAFKTGAPAENPR"
     gene            62901..63632
                     /locus_tag="PK679_00310"
     CDS             62901..63632
                     /locus_tag="PK679_00310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008193 - tRNA guanylyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(His) guanylyltransferase Thg1 family
                     protein"
                     /protein_id="HPC54438.1"
                     /translation="MRHRELYSNLVALPPLFIRLDGRSFHRFAESWALERPFDERFAN
                     AMARVGERLITESGLSPDLAFTFSDEINLYFSRLPFNGRVEKLDSVTASFAASALTIA
                     MESTEPVSFDARIIHVTPEVAPEYLIHRQGEAWRNHMNAYCQYILVREGMTRKEAAAF
                     LKGRPAREMHEVAFSRGVNLAETPAWQRRGILVRKRERKVKGFNPRAGKVEESYRSEV
                     VTDRNLPVFASPEGRALLSSILRSP"
     gene            complement(63612..66797)
                     /gene="ileS"
                     /locus_tag="PK679_00315"
     CDS             complement(63612..66797)
                     /gene="ileS"
                     /locus_tag="PK679_00315"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HPC54439.1"
                     /translation="MKEEKSSYQAGEIEEAVQAFWTEENIFRRVEEMRKGGEDFFFVD
                     GPPYTTGHIHLGTAWNKIIKDCILRYHRMCGRNVIARAGYDMHGLPIEVRVEQKLGFS
                     SKKDIERFGIGKFIEHCREFAATNKDVMSRQFLRLGAWLDFDDPYQTMHPGYIEAAWW
                     TLRRADEEGMLERGFRVVNWCPRCATAIADAEVEYWDETDPSIFVKFPVEGRENEYIV
                     IWTTTPWTLPANVAVAVNPDFTYARVEATKGGRKEILWMARELIENVLKKGRYQDYTV
                     LSTCPGTDMQALSYTSPLRDQVPAQRQIRHRVVPADFVAPENTGIVHIAPGHGWDDYV
                     LGCREGLEILCPVDIHGRFTGQGGKYANLFVKEADPVVMADLGSHLLAQESVVHRYGH
                     CWRCKTPIIFRATEQWFLKASQMRDRMLEEVAKVTWYPDWAGSARFHDWIKEARDWCI
                     SRQRYWGIPIPIWTCGSCGTYRVIGTFRELEEASGTTVTDPHRPWVDQVEIPCACGGV
                     MRRVEDIFDVWFDSAVASWATLGFPGRKDDFERLWPADFITEGQDQTRGWFYSQLGAS
                     VIAFGKAPYRSVLMHGFALDAEGRKMSKSLGNVVTPEEVIRTQGADVLRLYVLSQNAP
                     WDDLRFNWEGVRNTARAINILWNVYRFPLPYMILDRFEPSSRGGMWEGTYVRENFSSL
                     EPVDRWIVSRVNNLAAQVTGDISSCNLHRASRALVQFVLEDLSRWYVQLVRERMWLEG
                     ESPEKTAAYETMYYVMRVLLALAAPFVPHVTEAMYRNMKLEKDPQSVHMLPWQKGDPA
                     LVDRQLEEMMEAVRSFDEAQANARQAGKRKLRWPVKECVVVTDSPGIAGAIGTLAPIC
                     RERANAREVRAVLGHWDRIGWKAEPVMKALGPAFGKNAPRVRELILAADGNAMKAALE
                     SGGVFVLSDGNARYEVTPGQVTFVEQLPEGICSAPMQGGTVYVDTTLSPDLEAEGYAR
                     EIIRRFQEMRRQLDLRVEDFVRATARIPDERICRMVAETWKKGIMDEIRAVSLDFSCD
                     QSPAGKDADLVRDWDVEGVSMTLSLSRAAQD"
     gene            67140..68606
                     /locus_tag="PK679_00320"
     CDS             67140..68606
                     /locus_tag="PK679_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HPC54440.1"
                     /translation="MDSTGDRQDPGLTGHGCIVGGEERFTGDIRTVRFPFTGEPFACV
                     HQAREKDLDDAVASAARGFSATRELSGAERYRILMALSDLVRKESENLARVLVMEGGK
                     TITFARSEVQRAIETLRVSAEEAKRLGGEVIPLDWTPGNEKRFGITRRMPLGVVVGIV
                     PFNFPLNLACHKIGPAVASGNAVVLKPATATPVSALMLGKMLLSAGFPAPALSVVPCP
                     GGRAERLVQDDRVSFISFTGSAEVGWALRLKAGRKRVSLELGGSAPVIVHEDADIAFA
                     ASRIVQGGFSNAGQVCISVQRVLVHEAVHDQVCREVCRGAKRLVTGDPRRGETTVGPM
                     ISREAVEKALGMVREAQAQGAQVVTGGRADGTLMYPTVVSGVTPGMRLFREEVFAPVV
                     AICSYRDFSEALSLANATPYGLQMGLFTRDINRILEAFGEGEFGGIMVNDVPTFRVDH
                     MPYGGEKASGLGREGPRYAIEEMTVLRLLSFNPEGGSR"
     gene            68513..69064
                     /locus_tag="PK679_00325"
     CDS             68513..69064
                     /locus_tag="PK679_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00725 family protein"
                     /protein_id="HPC54441.1"
                     /translation="MGTREGRSPVRHRRDDGAPSALFQPGGGFPVTGPARPVQIAVIG
                     AGDCSREEERAAGEIGRTLAENGAILISGGMSGVMEASCRGAASSGGIAVGILPGTGD
                     GNPYLSVRIRTGMSHARNYLVVESADAVIAVGGGYGTLSEIAFALKAGKPVYGYRTWD
                     IPGVCACPTPQDACFKALSAAHR"
     gene            complement(69036..70886)
                     /locus_tag="PK679_00330"
     CDS             complement(69036..70886)
                     /locus_tag="PK679_00330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032324 - molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin biosynthesis protein"
                     /protein_id="HPC54442.1"
                     /translation="MKRYLSVVSLQEAKEALAGTPVPCREKSVPLMEACGRVTARALF
                     APYSVPGEHIAAMDGIAVRSADTSGASEQSPVILKDAVLVNTGNVVPPGYDAVIMIEE
                     VWKEGDAFLIRRPASPWQHVRPPGEDIAESEMILPSGHRIRPQDIGALATYGITEVPV
                     RYFRAGLIPTGSELVPPGTRPGRGQVVESNTRLAEAWLAGHGGECTRYPPVRDDPPLI
                     REAILSAARENDLVIVSAGSSAGTRDYTADVLADVGRVVVHGVAIKPGKPVIIGAVGK
                     IPVIGMPGYPLSALTVLRELVSYLLSVSGIPVYGCAEIDARLTATLHSEAGVDEFVLV
                     SCGNVGGQWVATPLSRGSGVQMSAVRSNGYICIPASVEGFSAGEQVRVRLSEGMDRAA
                     SAIVVTGSHDPALDVLADILNARGTGLFSAHAGSMGGLLALRKGDCHAAPMHLLAENG
                     DYNVPFIAKYLPGTGIELVCVAGREQGIMSKTGLSLDDLPGKRFINRQKGSGTRMLLD
                     HELHRRGISPRDIPGYDREVPTHTAVALAVRSGEAEAGMGVASAARAFGLSFVPVASE
                     RYELAIPVSALDDRRVQALVDAVSSPEFRTALEKMGGYRTEITGERRRVP"
     gene            complement(70883..72088)
                     /locus_tag="PK679_00335"
     CDS             complement(70883..72088)
                     /locus_tag="PK679_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030151 - molybdenum ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HPC54443.1"
                     /translation="MSLFLKTVPVGEAIGIAARIARPLSPEDVPLEEAVGRVLARDVY
                     PDLDIPGFDRSVVDGYAVVASDTTGAGESIPSFLTLLATVRMGEGAKSEVREGHCVYV
                     PTGGAVPPGADAVVMVEDCEVIGDQVLVKRPVGIGENIVRRGEDFSRDRPALRAGRRL
                     RPADCGVLAAIGCPTVPVFRMPRVGVISTGNELVSVHDVPGEGKVRDSNGPMIAAYLR
                     RCGCREKTYGIVPDDREALALALRRALAENDAVFLSGGSSKDERDLTADLIGELGQVL
                     VHGIAISPGKPTIIGRCGEKPVIGLPGHPASALVVLDRVARPLLAALSGETSRVENTV
                     LAVLAENIPSARGREDYVRVRLEGGRAVPLFGKSGLLNTLAESDGMVRVPAGSEGLEA
                     GTTVGVLLW"
     gene            complement(72085..72261)
                     /locus_tag="PK679_00340"
     CDS             complement(72085..72261)
                     /locus_tag="PK679_00340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54444.1"
                     /translation="MDEEKVRKAFEAEGIEREIKCPQAFALSEKYGIPKMDIARYCNA
                     HGIKIRACQLGCFK"
     gene            complement(72480..73166)
                     /locus_tag="PK679_00345"
     CDS             complement(72480..73166)
                     /locus_tag="PK679_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC54445.1"
                     /translation="MKVSFRILMGVLVAGFFLAVLPAGAEPLIGGDQAWYAVHCNVDG
                     ASVYFDGEYKGDIQGNVLNVPVYTTGTPYKTYSVRKEGYTTFSDSIPGVPGKGETFDL
                     YATLNPTQPTQPPLIGGDIGWFAVHCNVDGASVSFDNTPQGTITNGILTVQVYTTATP
                     FKTYTVTMAGYQPYTGTIDRYPGKGETVDLYATLNPAPTPTPTKSPLLTILVLVAVGT
                     AGLLAVRRKE"
     gene            complement(73309..73500)
                     /locus_tag="PK679_00350"
     CDS             complement(73309..73500)
                     /locus_tag="PK679_00350"
                     /inference="COORDINATES: protein motif:HMM:NF012999.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC54446.1"
                     /translation="MSTVKPILWKYSFGDGFMATQQNATHTYRKPGTYNVTLTVWTMG
                     PDKIPVTHKVEKTGYITVT"
     gene            complement(73518..75749)
                     /locus_tag="PK679_00355"
     CDS             complement(73518..75749)
                     /locus_tag="PK679_00355"
                     /inference="COORDINATES: protein motif:HMM:NF016906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HPC54447.1"
                     /translation="MAGEYHEHIVVNKTLTIEGEDASTTVINGSYSGNGVTIVADGVV
                     LKDIQVTGSARYMPYDEKWPGYGIGAFHITDVTVDSCKVTDCQVGIYGSFTSGFRVTG
                     NEVFQNDVEGIYLDHPSLTTCSENTVHDNTFGIYVDSSEGRFSCRNNTIIHNKETGLC
                     FFDDLGNAEVEGNLIQDNAYVEFEQPGDAGSAGGYFAWLENATIRNNRFIHNGGVGFF
                     IDGMSESLVEGNIMEDNYAGFSYHDGNSAPGNTVTLSNTVDGLPVLYLEGVQDRDITG
                     SEYATIYLVGCRNITVHDMVMASRNGFGILLRGGEHITIRDNSISNNLYQNILVSAVE
                     NAKIVSNRLEGAMYGAGVIVSSFVNLTGNHAVGNSRGLAAASENEHVWFSNNILEGNK
                     IGFSFEYEHGREISVTGNRIVGNDPSLDIRDCGIFILDSDRIHFWNNEVSSVYQSVFL
                     CGGEMNIFVDNTMNNCTYGIELAPDLPVPAKSNRVINNNISAEKIAFFIGLPDTYVYS
                     NYIYLNNFRSVEEPPAITGIFHPPGWFMPDSPGTPLAWGLPSSGNLTAPLVPETGTPF
                     KDNTFNTEDPVFYNYGGKTFKGYLGNYWNWYAGTDTDGNGVGTTPYPVRVNNTDRYPL
                     LAPVSSYEIDPSPSFREDFDASPSVGVSPLTVQFTDHSTGNPTRYLYRFGDGFMSMSK
                     NPVHTYNRPGNYTVSLTIWKMDGRKMVNATTIRPAFITVEKKTEPEVEIDFTGTPCPG
                     KPR"
     assembly_gap    75919..76018
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(76226..76936)
                     /locus_tag="PK679_00360"
     CDS             complement(76226..76936)
                     /locus_tag="PK679_00360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54448.1"
                     /translation="MISFLNVLSALMIRKIGKDDYGEIAGYSAGMLFLVASVLVQGFF
                     LFSEQFVVALLLFGFIMARESRYVPAGILVGLACGYKQYAVLALIPFLYLMNSRKESH
                     WYTLLLPAFAVIAGIFGMFSVIYGPAAALNALVWTFGIGPMYLQGTLVGVPDYHATSV
                     IGLAVNLLASIVMVFPTLLFAIASSIKRGFRTPEERVIGLLALVFLLTILIRQYLHYW
                     ILALPFLALLACREFSDK"
     gene            77611..78924
                     /locus_tag="PK679_00365"
     CDS             77611..78924
                     /locus_tag="PK679_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0051499 - D-aminoacyl-tRNA deacylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HPC54449.1"
                     /translation="MKIALVSSLRDPGGSTIHDALLSLLGDPHEAYPLERHDLVHHRV
                     EDRLIYKDHIDREIDADLIIFLSRHSSVNPVPVLTVHVTGNISSADFGGRERSLAPAA
                     PAWMHAVLRELSKNAPHPYRVAYEVTHHGPTELSTPSFFAEVGSTEREWRHRAAGLAV
                     ARSVLSADPVDCIPLIGFGGTHYAARQTHIALTTRGAFGHIAHSREVPTLDAGIIRRM
                     REKSGAVAACIDRKSLSSGELATLQEMLAQEGIPIVTEDHLAHIGNLSWDSYQKILSL
                     AGDIVPGGRVTLCGEWPDGTPVVIELFPDLLEETLRCNAAEFMKGADLVPVARISTSK
                     SPVLPRFITIREQRDDVLHHLISLCVNILRRGESTSIEKDCLTIRRRTFDPEKAQDLG
                     VPRGPLFGRLMKGETVLVGGREITPDMVTAKTERRIHIPGLEKFV"
     gene            78921..80012
                     /gene="ftsZ"
                     /locus_tag="PK679_00370"
     CDS             78921..80012
                     /gene="ftsZ"
                     /locus_tag="PK679_00370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HPC54450.1"
                     /translation="MRSIVEEALTRVSQEMPDARKNNEDLDQILKELRTEIAVIGCGG
                     SGSNTITRMKEEGIHGARLIAINTDAQHLSRTVADQRILIGKQKTRGLGAGSIPQIGE
                     EAALENEEEIKRAVAGCDMVFITVGLGGGTGTGAAPIVAKAARDEGALTIGVVTLPFT
                     AEGVIRMENAEAGLERLRDVADTVIVVPNDRLLEVVPKLPLYAAFKVADEVLMRAVKG
                     ITELITLPGLVNLDFADVRTVMERGGVAMIGVGESESEEKAADSVKKAIRSPLLDVDI
                     SGAHAALVNVVGGPDMTMEEAEGVLQEVYNRISPDARIIWGAQIDPNMQNKMRTMLVV
                     TGVRSPQIYGRNEKITPKVQKQFEIDFLK"
     gene            80019..80213
                     /locus_tag="PK679_00375"
     CDS             80019..80213
                     /locus_tag="PK679_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase SEC61 complex subunit gamma"
                     /protein_id="HPC54451.1"
                     /translation="MEIAKPDVKFNINEELFRKYWRVIKLARTPTREEFQKIALVAAA
                     GVLIVGLIGFIIYELMLLVL"
     gene            80219..80692
                     /locus_tag="PK679_00380"
     CDS             80219..80692
                     /locus_tag="PK679_00380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor Spt5"
                     /protein_id="HPC54452.1"
                     /translation="MEEQVNRIFAIKTTSKQERTVADNIKKAIETGATDIKVVAIIVP
                     DELKGYVLVETPESLARIEQLAEKVAHARTVVRGETTLPEVAHFLVPKPVVSGISEGT
                     IVELIAGPFKGEKAVVKRIDTGKEEITVELYESVLPIPITVRGDNVRVVDRGEGT"
     gene            80796..81272
                     /locus_tag="PK679_00385"
     CDS             80796..81272
                     /locus_tag="PK679_00385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HPC54453.1"
                     /translation="MAEVVEVLVAGGKATAGPPLGPALGPLGINVKAVVDEINARTAS
                     FNGMQVPVRVEVDDKKNFTVSVGVPPTTALIKKEVNVEKGSPEPNVKIVGDLPIEAAV
                     RIARMKQGDMLSYDLKSGVKEVIGTCVSMGITVDGKRAKDAQKAVDAGTYDKLLVE"
     gene            81327..81971
                     /locus_tag="PK679_00390"
     CDS             81327..81971
                     /locus_tag="PK679_00390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HPC54454.1"
                     /translation="MVERAKIVEAVKAAIEKAPSRKFAESVDITVNLKNIDMAQPKNR
                     IDETILLPHGTGKKVGIAVLGKGDITTRAREAGADLIIGPEEIERLGGAPREARKIAS
                     MYRFFIADTSVMPQVGRFLGPRLGPRGRMPMPVPAGTDIKPIIERLRNSVKIRTKDKK
                     TFHVKVGSTGMPPEQIAENIDTVLRRVESVLEQGPMNIRSVYVKTTMGPPQRVV"
     gene            81973..82827
                     /locus_tag="PK679_00395"
     CDS             81973..82827
                     /locus_tag="PK679_00395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HPC54455.1"
                     /translation="MVLYTHHLPAWKRKEVEEIKADAGKYTLVGLVDMYGIPASQLQQ
                     IRRNLRSKAKIKMTRNTLIRCAFDEVGEPVALLKPHLSGHSALIFTNENPFRLYKTLE
                     KTKTKMAAKPGETAPADIVVEKGPTSFKPGPIVGELQQAGIPAAIEAGKVKIRETRTV
                     VKKGEVISAKLADVLAKLDIKPMDVGLSLQAALFEGSVYEPSVLAIDEDLIYSQMQLA
                     AVQAFNLSVNAVIPTKETAVPIVEKAAREARSLAIEAGVYSKDVIDAIIGKAYRESVA
                     LRGVTGEH"
     gene            82856..83173
                     /gene="rpl12p"
                     /locus_tag="PK679_00400"
     CDS             82856..83173
                     /gene="rpl12p"
                     /locus_tag="PK679_00400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein P1"
                     /protein_id="HPC54456.1"
                     /translation="MEYIYAALLLHKAGKEVKEENVKAVLNAAGIAVDDARVKAMVAA
                     LEGINIEEAIAKAAAAPVAAAAPAPAAAAPAAAAAAAPAPSKEEKKEEEESGMAGLGA
                     LFG"
     gene            83381..84556
                     /locus_tag="PK679_00405"
     CDS             83381..84556
                     /locus_tag="PK679_00405"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HPC54457.1"
                     /translation="MDTLPALLIVLVVAKVLGELVERAGFPALVGEIAAGALLGPALL
                     GIVTMDDTIGTFADIGLIVLLFTSGLQLNMRSFRNSVRTGFSVALWGVIIPLLGGTAA
                     GLVLGFGHVESLVIGITLSITSIGVSLRSLIDLHQLKTDVGLAIVSAAVIDDAIGIVL
                     LGSLSALALKESQVSNLAVLLLLAALFIGLLLTVGRRALVWVFKASQKAHTHEMSYSV
                     ALVLGLLTAVLSNGAGLHYAIGAFLAGLVLGDSIRSDQTLYDSLFDVAFGFFVTIFFA
                     SIGLLFPSDLSHFSVFLLVALFLLALATKTAGGLAGALPAFKNYRKSFLVGLGLCPRA
                     EVALVVVKVSLAAGLLSAALFSTLTIVIIGTVLVTPLLLAWGFSSPKKGQESPSDAR"
     gene            complement(84529..>85016)
                     /locus_tag="PK679_00410"
     CDS             complement(84529..>85016)
                     /locus_tag="PK679_00410"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54458.1"
                     /translation="GGRSQGGGRNGKGSSPDTTPLSDLVSGTFIKVGPRTPLDTCIRH
                     IVGDRCSDLYVTDEEGHFLGVITPFDVVAHLGPGMGVRSRKKSHHLGPLLSRDDLCAE
                     DIMSRGHIAVMQDTPLSEALRLMEKHHHPDLVVVNREGVLVGIVDVCSILSYLASEGD
                     S"
     assembly_gap    85017..85116
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(85221..85751)
                     /locus_tag="PK679_00415"
     CDS             complement(85221..85751)
                     /locus_tag="PK679_00415"
                     /inference="COORDINATES: protein motif:HMM:NF019610.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M54"
                     /protein_id="HPC54459.1"
                     /translation="MELLIFWDSGAPAGIQASFCRELAALLPVVPRLCENPLLVTGYR
                     PERRQTDASVLLDSLDIYKRRSGVCDPILLVVSEDLCRDGDEYLFGLARPETGNAVVS
                     TSRLANAHYGLPPDEEELFDRLVKEAAHEVGHLLSLAHCRCRECIMYNPLTLEDLTRQ
                     KRWLCPVCREQVRSVL"
     gene            85764..86192
                     /locus_tag="PK679_00420"
     CDS             85764..86192
                     /locus_tag="PK679_00420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0146 family protein"
                     /protein_id="HPC54460.1"
                     /translation="MVMAGLKRIERLIASYIAENYRSAAEVGAGKNLEVARLLQERGV
                     SVFCTDIAPPPPDPGVPFIRDDIFSPQAGLYRGCDLIYSVRPHEEMVPALVRLARTVD
                     CDLLVYHLGFEGYGNGGEIIDCGVVLHRYHRCQNPSKSVF"
     gene            complement(86165..87571)
                     /locus_tag="PK679_00425"
     CDS             complement(86165..87571)
                     /locus_tag="PK679_00425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication factor C large subunit"
                     /protein_id="HPC54461.1"
                     /translation="MDWAEKYRPAHLDEIVGNTAILHQMLDWARGWDAGKKPLILYGK
                     PGTGKTTSAHALASDMGWEAIELNASDQRTRAVIEKVAGSGSTTASFSGKRRLVIIDE
                     ADNLHGTADRGGARAILELLRVARQPVILIANDLYAVPGEIRNRCEALQFRAIQARSI
                     VPRLRFICSAEKIACSENALKKIAESAGGDMRAAIHMLQAAAAGRDRLDEDISISAKD
                     TRSTIFDVIGALYGRTDPESLLRLAYDADEPPDTLIQWIEANVAGMDRIQDLDTAYSA
                     LLRADTYIGDTYRLQYYTLWRYAHALMLLGVARVTAGKGIHSRIMPPERWKRISSYQK
                     QKTVRASFLRKLASGLHMPERTLLEEYMDPLCLLIDHDPLTAAREFGLDADELALAIH
                     DRSRAASVIKTLAAEEKEKEVRREKEKKEKAARSRKKDEEEPSFVPAPAPEPVLPEQG
                     GAPARSPPKNQKTLFDGF"
     gene            87653..88663
                     /locus_tag="PK679_00430"
     CDS             87653..88663
                     /locus_tag="PK679_00430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 2 protein"
                     /protein_id="HPC54462.1"
                     /translation="MELNGVSTAEIALSVREYEGVRRKQAIGEMVRALRIDSPGILAS
                     FGEDAAVIEHGDEVLLLAADGIWSRLMEADPYWAGYCAVLVNIHDIAAMGGRPLAMVD
                     VFSISDTTIQNKVIAGMHDASLQFGVPIVGGHLHPDTPYSVIDVAILGIAQKDAVIYS
                     HTARTGDSVIVAVDLDGRVHPSCSLNWDSVTMKSPGLVRAQVRVMEGLARDHLVTAGK
                     DISNPGVIGTLGMLLEVSGRGATIALERLPTPDLRRHGMTFEQWVRVYPGMGFVLTAP
                     RGSVSEICRRFSEVGMTAAEVGAVTDERTLSISLDNEKTPVFSLDRTGVMRLFSGGEP
                     CR"
     gene            88654..89421
                     /gene="mtxX"
                     /locus_tag="PK679_00435"
     CDS             88654..89421
                     /gene="mtxX"
                     /locus_tag="PK679_00435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker protein Mmp4/MtxX"
                     /protein_id="HPC54463.1"
                     /translation="MPVRRIGIGVAADGARVQESARKAGIDSRVIFYAKPGLLDAGQD
                     FGIEEGDEPWKMLVGDLYAGKIDAAVRGTLPSGATLRVLREAAGVDHLERAALLEDGK
                     GRRFLLAPVGIDEGWTVVDRVAIARRTKDLAGILGLEGGVAILSGGRLSDAGRHPRVD
                     ESLAQAELVARLTGFPHFEILIEDAAEECSVIIAPDGISGNLVFRTLALLGCGQGHGA
                     PVLNIDRIFIDTSRASPSYANAIRLAEFLVRSAKTRF"
     gene            89603..89809
                     /locus_tag="PK679_00440"
     CDS             89603..89809
                     /locus_tag="PK679_00440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFYB/HAP3 family transcription factor subunit"
                     /protein_id="HPC54464.1"
                     /translation="MADLPIAAVVRIAKKNGAERVGSDAAAALVAKAEEYIANLTKEA
                     NRLALHAGRKTIKEEDVELAAKSA"
     gene            90031..90390
                     /locus_tag="PK679_00445"
     CDS             90031..90390
                     /locus_tag="PK679_00445"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC54465.1"
                     /translation="MAIHTQGVAEETRCDIIHSIYDLGKKGQPAVDFLLLALKDEDKR
                     VKIAAANALCDIGDARCVDALIALLSDGDKDIRFVSASLLGKIGDPRAREPLTRACAD
                     ENCFVRIMAKEALHRIR"
     gene            90480..91304
                     /locus_tag="PK679_00450"
     CDS             90480..91304
                     /locus_tag="PK679_00450"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54466.1"
                     /translation="MASTGKINVTYPTVVDRAYQEYKRHRKVSDIMSSGVVITTPQTS
                     MIEAARIMGERRIGSLVVVRYGTPVAIVTERDLLSKVFAADLDPADVSVEDVMSFPLI
                     RVCPDIEIREAARTMIRKKGRLTVFACGELCGIITASDLIREMPDARETSMTVNDFMT
                     KDVVYVGEDEKISDVVRIMGTERIGSVIVTTGGNPSGIFTERDLLSTLMARGAALDVP
                     VGEVARSPLISAPAGISIHKAARIMAENHIRRLLIIKRKRIAGIITARDLVEAYAL"
     gene            91413..91919
                     /gene="msrA"
                     /locus_tag="PK679_00455"
     CDS             91413..91919
                     /gene="msrA"
                     /locus_tag="PK679_00455"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HPC54467.1"
                     /translation="MQDENGLEQATFAAGCFWGVEAAFRRVKGVVETWVGYTGGNVPE
                     PTYEEVCSGSTGHAEAVRIIFDPRIVSYDQLLGVFWDIHDPTQVNRQGPDIGTNYRSA
                     IFYHNDDQKRKALASRDRVQQSPRMKGKKIATEIVPAGPFWKAEDYHQQFYEKSGWGY
                     AARPKYWE"
     gene            complement(91952..92389)
                     /locus_tag="PK679_00460"
     CDS             complement(91952..92389)
                     /locus_tag="PK679_00460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HPC54468.1"
                     /translation="MPDPAARELLSAEFPLANRIWLDYHQTKGDPVTDRIFAAFAGGR
                     AVSVARCRRHPDGLEVDAVFTPVEHRGRGYANLAVGALVEACGHDTLYMHSVLNLTGF
                     YQKFGFREIPEAELPPTIRERFAFAGGELEGANVCPMKRDPPP"
     gene            complement(92474..93556)
                     /locus_tag="PK679_00465"
                     /pseudo
     CDS             complement(92474..93556)
                     /locus_tag="PK679_00465"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(93918..94469)
                     /locus_tag="PK679_00470"
     CDS             complement(93918..94469)
                     /locus_tag="PK679_00470"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HPC54469.1"
                     /translation="MFLVSDLHINHARIIGYCNRPYRSVSEMNRDLVSRWNSVVGAGD
                     TVYCLGDFCMRGNPVPWIRALRGRKVFIRGNHDNALLRARHHSVISYGGYTFYLVHDP
                     CDVPDSWKGWVIHGHTHNNRMDIHPFINGIRRTINVSCECTGYTPVSLDRIISLDLDT
                     IERMETLSDRPVRKGHLVPGKEW"
     gene            complement(94629..94820)
                     /locus_tag="PK679_00475"
     CDS             complement(94629..94820)
                     /locus_tag="PK679_00475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0006725 - cellular aromatic compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase family protein"
                     /protein_id="HPC54470.1"
                     /translation="MPVVTVTMARGRSYEQKKRMAEEIAGTVSRILAVPPERVTILIH
                     ELEKENIAIAGTLLSEQQK"
     gene            complement(94939..96147)
                     /locus_tag="PK679_00480"
     CDS             complement(94939..96147)
                     /locus_tag="PK679_00480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HPC54471.1"
                     /translation="MEPEREEIYREALALHAEHRGKLEIRSKVPLETRRDLSRAYTPG
                     VAEVCRAIQKNRDLAYKYTLKGNSVAIVTDGSAVLGLGNIGGYAAIPVMEGKAILFKK
                     FAGIDAFPICFERYQTDFVDQVRNIAPCFGGINLEDIAAPRCFEVEDALQDIGIPVMH
                     DDQHGTAIVVLAALLNACRATGKQFEDLRIVICGAGAAGYAITRLLRCIGYSPDVCRS
                     VKDIVVCDRQGIIHRAREGLYRNKYKFIIADETNRSGRAGTLADAMEGADVFIGVSAP
                     GIVTEEMVRKMNDNPIVFAMANPVPEIMPGEAKRAGAAVVGTGRSDFPNQINNALAFP
                     GVFRGALDAYATRISDEMKVAAAHALADYVEKPHRDHILPTALDRDVTRAMAAAVRQA
                     AIDSGCARDL"
     gene            96259..97167
                     /locus_tag="PK679_00485"
     CDS             96259..97167
                     /locus_tag="PK679_00485"
                     /inference="COORDINATES: protein motif:HMM:NF012774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HPC54472.1"
                     /translation="MPDRAVLSLLFVGILAACAGCTLTFGDLHPGGNGSANGCGFTTH
                     ALVTRVIDGDTFSVRYPDGSDDTVRILGIDTPETDDAGNSKDVFPGIPDPSFLTSWGK
                     RASSFSRDLLLGEDVILSGDCRAGTRDRYGRLLAYVTSKGTDAGSLLLREGYARVYTG
                     EDFSRKEEYLALQQDAWERGVGLWNPARVPGEAGNGPVRIAYVQYDAPGDDRENLNGE
                     YVSLVAEERTDLAGWTLCEGDGALYRFPSLTLEAGDSLVIHTGSGVPGGGDLYWNQTI
                     PLLGNSADSVVLKDPAGKSVSSYTWG"
     gene            complement(97175..99187)
                     /locus_tag="PK679_00490"
     CDS             complement(97175..99187)
                     /locus_tag="PK679_00490"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B DNA-directed DNA polymerase"
                     /protein_id="HPC54473.1"
                     /translation="MWILDSCARGGRVEFWEKGRGGRHVTRPAPPSFLLHLPDPHYHR
                     DLVEGLESRYRVEECAIRTIHGVLDGYRVWAGKDVAARIEEQTRYEAQIYDADIRPDL
                     GLMAEGGFFPCSEDGESRFSVDFSPDLSVVEILPAGNPFVSGPLPALVLVADGRRERL
                     EGDEKTILADLEGVLSSADPDVILFPHADLWVPRMVARARGLGTGTGLSRSGRFRRLS
                     QKSYWSYGRTEFRAGALIPDGRLLIDTTGSFHYRESGLLGILLGSRLSCLPPNLVSRF
                     SSGTLISSYEVYEAKRRGIAVPWRKADAESVRRLPDLRAADRGGMIFQPAPGIHDRVF
                     EIDFTSLYPSLIVRDNLSPETLTCPGRRGFLPDVLEPLLTMRRRTKELKASDPRYAGR
                     DALLKWMLVTCFGYTGYRNAKFGQIEVHEAITGSAREVLIRTRDIAGEMGFSVLHGIV
                     DCLWVKGGDIRALRERVERETGLHAVAGTYDWIVFLPMADGTGAYNRYYGRLQDGSMK
                     VRGVAARRGDTPPYIRDVQHRMLHVLGSAATLPAVAGLRDPLQALYREARDALPAADP
                     AGMAVTRRISTLSYRHACAEASAVEACRAEGIDLFPGMEVRFVVTDARTWSVDLDWKA
                     ARFDAGYYRGLLEKAWEEVIFAVDQACLAVHGGQSRQEPSPLPATR"
     gene            complement(99174..99416)
                     /locus_tag="PK679_00495"
     CDS             complement(99174..99416)
                     /locus_tag="PK679_00495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54474.1"
                     /translation="MGRSFTSVRQEVRALTERWERAARTLPGRDREVALRVARMAGAH
                     ASECFYAFDDPLEAALFSVLLELAGECGEGAGRVDP"
     gene            complement(99418..99945)
                     /locus_tag="PK679_00500"
     CDS             complement(99418..99945)
                     /locus_tag="PK679_00500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54475.1"
                     /translation="MELVLGPSVTLRSGTFSAVVAPEDVVLAGLNDNPVLSRFLFLFV
                     SGNYSRLLSGINRRTVSIEVRRAFTAFQLLQILRESYHTIVFVEHDPTLYDGAGGVAH
                     QVGEDLRQLGQGALVVLYTAFPDPSFEAIAGLADRVFYLASPAAGLPAPRARGRGKIR
                     FPGKLPRGQQTLEGV"
     gene            complement(100068..101579)
                     /locus_tag="PK679_00505"
     CDS             complement(100068..101579)
                     /locus_tag="PK679_00505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="HPC54476.1"
                     /translation="MKDASSPQETSFGLLVFSISLAIFMSSLDGTIVNIALPTISEAF
                     GISSSTVSWVATAYMLVLAGCILVFGRISDVVGLRSVFLSGFAIFSAGSFFCGMLPDL
                     FHSFPLLVASRVFQAIGGAMMTAIAPAMVSVYVPGERRGAAMGTVMTLAALGTALGPA
                     VGGVLIQYLSWNWIFLINVPIGMGAVLLGARVIPPVERPAGTKRFDVQGAILVFCGLA
                     ALIFSVTEAPALGWTSPVIVASVALSGAALLFFVRREVSTDDPILDLRLFLSRNFSLS
                     NLILALVFLSFAGISYLLPFFLEYVKGFPPSVSGLILTAFSAGMMVGGIVSGFLYNRA
                     GPRPLSIGAAVILLAGYFMMWHLKVDTTTMSIVACLITIGLGMGLLITPLTNMIMNAV
                     PRSYQGMVSSLTSLERYVPITLGIAIFNLVFIQGVTSIARHRGVTASAPATLTLPVLA
                     AGFDLAFFGSFLLGLIIVILTLIVREEVHPDFRGGEGGDGADHAGEQQPFLGI"
     gene            101791..103128
                     /locus_tag="PK679_00510"
     CDS             101791..103128
                     /locus_tag="PK679_00510"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC54477.1"
                     /translation="MIRLLHVDDDSVILELAGLFLSQAGDFSVDTATSGESAIGMLSR
                     QEYDAIVSDYTMPGCSGLDLLKYVREKDKNTPFLIFSDYNDEEVVIDALTSGADFFLP
                     KGLHVRSQFIQLEHAIRESVMRRRAEKQHDDVSARLKVMEAAIRGSPHPLCFCDIYGR
                     IRFANRASIELWGYSDDTEIIGKHAIEFVVSPEIDTRAIPDLLTMKGWSGQAVALRKD
                     RSTFDAQVHVNVIHDDSGIPLGFIASFTDITLQKETRSRLEAYIRAMRFVSEKASELA
                     EFPLDGDIYSFIADSLARLAPEGSAVLVSSVQPGPVLRLESVRADREIIAEATRIIGR
                     PLEGLEFDLPAEKQDLSFPPVFVDIAGGIKELSFGRIPDETCKKLEETGSFGRITGSG
                     LVWGGKTHAVTVLLLPRGSHLENTDVLNLFTLHCSAVLQRREAERMLRNLRTG"
     gene            103400..103915
                     /locus_tag="PK679_00515"
     CDS             103400..103915
                     /locus_tag="PK679_00515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54478.1"
                     /translation="MKSRDIAIVGILLAIGAILRYFLAMLHTPLTPNMIIAFYCLAII
                     LVRPRVHEALGIGIVAGILSMLISSSIFPPANLISEPVGALVCFGLYAILKEKTGTPA
                     VTTFVTTLASGFSFAAVALLAVAPKILDKYSTVFGFVVVFVPIVVITAFFNAIIVQIL
                     YYPATRVLSRG"
     gene            103919..105355
                     /locus_tag="PK679_00520"
     CDS             103919..105355
                     /locus_tag="PK679_00520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC54479.1"
                     /translation="MITLEDVSYRYQRGGRDAVSGISLSVSPGECLMITGPSGAGKTT
                     LCMAASGILEHEFGGEKRGRVTILGKDVREYPGLPEIASHVSVVFDDPEAQLIFTTVE
                     EEILSALERSGLSPAEIGQRLASILEITRLAALKDRPPHALSGGQKQRVALAAALALG
                     TDILILDEPTAELDEEGTASIVSVLRDLKAQGKTILLTEHKYSHFRDLVDRLVVMEGG
                     RFRAIGTPCELITDRSVAEIVIPDFSGIRSSFPCRPHEGENPVISVRDLGFLYGDVPA
                     LAGVSLDVYPGEFVAIVGENGSGKTTLIKHFIGLLHATRGSVTVDGKDAKVTPVSELA
                     HSVGLVFQNPDHMFFADTVAGEVMFGITNLGIPEPEAVLGEVLSRCRLSGARDLYPRW
                     LSRGERQRLAIACVLAMQPKVIVLDEPTTGLDGKESREVMEILRQLQAEGRAIVMVTH
                     NHEMARECADRVVTMRAGRIVSDTRNGA"
     gene            105362..106141
                     /locus_tag="PK679_00525"
     CDS             105362..106141
                     /locus_tag="PK679_00525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HPC54480.1"
                     /translation="MGEILQYIHKDGLFHRMHPGTKIFFILVIGIMAILSLSIPFLCA
                     LLGVVLVMALAGRILREVLDQMKLILAMSVIFILITLVTMPEGDVLFHLLPGGLLPVT
                     TGALDAGIILTLRFAILIMAFQIFVITTQPRDLVNTLEKMRVPIEYNLMFLIALRFIP
                     TLQIEARKIHEAQLARGYSTGKGFVGRIRSVAPVMVPLVSNALSRANILGITIDMRGY
                     RTRKRTPIREERLNMPDKVFVGVLGFALAAYIAATLLQILR"
     gene            106261..106956
                     /locus_tag="PK679_00530"
     CDS             106261..106956
                     /locus_tag="PK679_00530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HPC54481.1"
                     /translation="MKYEIRYRPAYSLLVVTLSPGESIAAESGSMTYMQPTLTVRTQK
                     REKSLLGSLGLALAGGQSFFVNEFCATTAAGEAGFSAAPLGDIGTLRVSPGKGCILQK
                     SAYIASQGTVDLDVKWEGFSKGLFGQGLFMIRATGEGTLFINTFGAIDQHTLKEGESL
                     IVDNFHLVAFSDTCTYQVRKFGGIKETLLSGEGFVTEIRGPGDVFIQTKNIRELAEWI
                     WTLIEPRVQARAR"
     gene            107123..107260
                     /locus_tag="PK679_00535"
     CDS             107123..107260
                     /locus_tag="PK679_00535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54482.1"
                     /translation="MPTCSDCFLYVPGKGGKDGECRINGPAPPDRDAERCPSRTFRPR
                     Q"
     gene            complement(107291..107881)
                     /locus_tag="PK679_00540"
     CDS             complement(107291..107881)
                     /locus_tag="PK679_00540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HPC54483.1"
                     /translation="MRHWQVYPPDDDTFLLLGAALALVAPGERVLEVGCGSGFISARL
                     ASRAEVTGTDINPHALRQSRQAGVIDVVRADLLCGIRGPFDTVIFNPPYLPTRPDERV
                     DGWLGYALDGGEDGTAVIRRFAAQVGRVLAPGGRILLLVSSLSDPSRVRDTFSGQGFS
                     CSVYSEYRMEGETLFVFVFTATGEGRKETGRPEESS"
     gene            complement(107878..108648)
                     /gene="rsmA"
                     /locus_tag="PK679_00545"
     CDS             complement(107878..108648)
                     /gene="rsmA"
                     /locus_tag="PK679_00545"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HPC54484.1"
                     /translation="MSARFDQHFLVDRKAIERIAGIIRVEGRIVLEVGPGRGALTEAL
                     LERGARVVAVEIDPGLVEMLSERFLREIGENRLVVVHGDAVSCPLPGFDVVVSNLPYS
                     ASSKITFRLLETGFEEAVLMYQSEFADRMLAPAGTPECGRLSVMVQTYCAVGRVFDVP
                     PQAFSPRPKVRSTVLHIVPREPLFPIRDRDLYARVVRALFSHRRKTVRNSLKSAGSML
                     ESGLAEFLVKNLPEEILAARPEELYLEDFATIANMGAS"
     gene            complement(108645..109205)
                     /locus_tag="PK679_00550"
     CDS             complement(108645..109205)
                     /locus_tag="PK679_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF655 domain-containing protein"
                     /protein_id="HPC54485.1"
                     /translation="MKTEKKEIYAIVLDVLMKGHPDDPRPVFKREPLVQAVGVAQFKL
                     LELVPKTTDIQIHENVYIGDGEREKIERVKRRISYNDLTQTAKLELPFAVERIVKEKE
                     SEFVQFFNKSISISPKLHMLHLLPGIGKKLMWEILGEREKKPFESFADISQRIKSIPH
                     PDKMIIARVMEELQDPNVKYHLFTSR"
     gene            complement(109216..109566)
                     /locus_tag="PK679_00555"
     CDS             complement(109216..109566)
                     /locus_tag="PK679_00555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase Rpb4 family protein"
                     /protein_id="HPC54486.1"
                     /translation="MKVKAIIREERITLPELREVLSKVEAERIEAGREMSYELRKSIE
                     HANLLSKTTSEKSRLLVTELQKLEKMKPDIAFRIANIMPRTRDELRAIYAKEKYTLQP
                     EELDTIIELVKAHF"
     gene            complement(109602..109892)
                     /locus_tag="PK679_00560"
     CDS             complement(109602..109892)
                     /locus_tag="PK679_00560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21e"
                     /protein_id="HPC54487.1"
                     /translation="MAHHNGPRKKTRYKFKKDIRRQGIVPVTSLIQKFDIGQKVHVVV
                     EPSIQKGMPHRRFHGMTGTVVGQRGRAWLLSIRDGGKEKIVIARPQHLKAQR"
     gene            complement(109896..111125)
                     /locus_tag="PK679_00565"
     CDS             complement(109896..111125)
                     /locus_tag="PK679_00565"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0031119 - tRNA pseudouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(54/55) synthase Pus10"
                     /protein_id="HPC54488.1"
                     /translation="MDVTDLALRILAYGEICDSCLGRFFGKLSHGLSNRERGRALRIA
                     VFLQENRPFAEPATCWICGGLLSRVPEWAERVTRALQGLEYEKFAIGTRVPPLVAESE
                     EIVWSDLDLCHAEPLKSEMNREVGKAVARLTGKTADPASPDVVAILDIPGETVEVQVN
                     PVFFCGRYCKLERGLPQTHWDCRACRGAGCEKCGFTGKQYPDSVEEIIGRPAIRLFSA
                     ENAILHGAGREDIDALMVGSGRPFVMEVVAPRIRSVDLRDLEDGINREAGGKVTVSIE
                     RWGKREDVEIIKSAKGYKKYRILVEIEGSYTQDELQSAIRALKGAKVNQRTPLRVAHR
                     RADRVRERRVIDIRALGEENGRVILEITGEAGLYIKELVSGDQGRTQPSLSGILGRPA
                     RVCQLDVVYVQGNNEGE"
     gene            complement(111116..111694)
                     /gene="trmY"
                     /locus_tag="PK679_00570"
     CDS             complement(111116..111694)
                     /gene="trmY"
                     /locus_tag="PK679_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (pseudouridine(54)-N(1))-methyltransferase
                     TrmY"
                     /protein_id="HPC54489.1"
                     /translation="MIRIAVIGHLARTAGDFSLSDMPGGAGRMDIMCRCINSAFFLSH
                     SLRRDVECYLLLRGPPGPDKIVRFMGDRLRSLNPDERSAGALIRKALAIPAGTEFRES
                     SPGVEVKRGGPADLVSMAPFAVLDESGEDIRACSSLPENYILSDHLDFYPEEDALLKG
                     QKRISVGPATLHADHAIIVLLNEIDRRRAGWT"
     gene            complement(111701..113023)
                     /locus_tag="PK679_00575"
     CDS             complement(111701..113023)
                     /locus_tag="PK679_00575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein Srp54"
                     /protein_id="HPC54490.1"
                     /translation="MLDRLGTSLKDAVKKLAGKTVVDRAAVEELVRDLQRALIQADVN
                     VRLVMQLSEAIKKRALEEQPPKGMTVREHVLRIVYQELVRLVGSAGEVKLEPQVILMA
                     GLQGSGKTTTTAKLARYFQRKGLRVAVICADTFRPGAFDQLNTLCSRIHVPCFGNPGE
                     KDALKIVREGLKSLSSAEVIIIDTQGRHALESDLIREIIDIQAIASAQHRWLVIDAAL
                     GQQAAEQARKFHEAISIDGVIITKMDGTAKGGGALSAVAETRSGIVFIGSGETIDDLE
                     RFDPDGFISRLLGMGDLKALVEKAEETLAAAEVDVNAMLRGKFSLRDMYNQLEAVTRM
                     GPLKQIMSMLPLGNMEIPEDAYDITSTKMQRYRIIMDSMTAAEMDDPSVIGSSRIQRI
                     ARGAGASPEEVRELLRYYKMMKRALKGVRGGQGRFNMQRMLKKFGGGT"
     gene            complement(113023..114057)
                     /gene="ftsY"
                     /locus_tag="PK679_00580"
     CDS             complement(113023..114057)
                     /gene="ftsY"
                     /locus_tag="PK679_00580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HPC54491.1"
                     /translation="MFEGLRSRLQKITGSLEDRIEQTIPAEPSVEKTGVPGGAAPAEA
                     AKKDPSLLSRVKVLITDREFFISEKDVEEPLFELQMVLLENDVALPVADEIIRRVRED
                     LTGKRRKIGEPLHEIVTAALRNALMSVLGDGFDLVSYIRNHERPVRILFTGVNGTGKT
                     TTVAKVAAYLKKQGFSVVIGAGDTFRAGALEQIDVHADRLGIKVIQHQQGADPSAVLF
                     DAVSYAKAHRIDAVLADTAGRFHNRANLMNQLEKIRRVMNPDLIVYVDEAVAGNDAVI
                     RAHEFDRTVGADAVILTKADMDSRGGAAISIAHTIGKPVMFLGTGQGYDDIVPFSPAR
                     VVEELLGVSA"
     gene            complement(114075..114536)
                     /gene="pfdA"
                     /locus_tag="PK679_00585"
     CDS             complement(114075..114536)
                     /gene="pfdA"
                     /locus_tag="PK679_00585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prefoldin subunit alpha"
                     /protein_id="HPC54492.1"
                     /translation="MDAIDPRELQSLQIYLNEYRQQAEVFSQQLALLEEGRVEAMSAI
                     EAVKGIAESPDSTVLLQMGAGISVRARVENPGRVLVSIGSEVVVERSTEEAVEYLKDR
                     ITEMEASAKKVMETLEQIRAQMNEIGRRLEAGYHQYQAQQARAAQGGEPGG"
     gene            complement(114538..114729)
                     /gene="rpl18a"
                     /locus_tag="PK679_00590"
     CDS             complement(114538..114729)
                     /gene="rpl18a"
                     /locus_tag="PK679_00590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18Ae"
                     /protein_id="HPC54493.1"
                     /translation="MAEQKYEVKGDFRMGGEVRPFSKIIEAPSEMQAKERTFTLFGSK
                     HRVKRRYITIHSVTLLKGE"
     gene            complement(114736..115398)
                     /locus_tag="PK679_00595"
     CDS             complement(114736..115398)
                     /locus_tag="PK679_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-6"
                     /protein_id="HPC54494.1"
                     /translation="MERTISFGGIPHIGVFSRVLDDVAVIPPSAPAEFGEALRELLGV
                     EIIPTTVQGSEIIGSLLTGNARGFVVSGMATDEEISILREYREVYLLEHTMNAAGNVI
                     LANDSFAAVHPDMPAEMAGEIGDFLGVKVVPLTLGGVKTVGMAGVATNKGVLVHPRCT
                     RAEIQRVEEVSGLPVGTGSVNGGTGLVGTGLLVNSKGYVAGLETTGFELGRIEDVFGF
                     LE"
     gene            complement(115400..115663)
                     /locus_tag="PK679_00600"
     CDS             complement(115400..115663)
                     /locus_tag="PK679_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31e"
                     /protein_id="HPC54495.1"
                     /translation="MAEKVQEQIYVIPLREAKRAPRWKRSNTAIKDIRKFLARHMKSS
                     DVKLDRTINERVWDRGSEKPPSRIRVRAMKFDDGQVQAELAEE"
     gene            complement(115671..115823)
                     /locus_tag="PK679_00605"
     CDS             complement(115671..115823)
                     /locus_tag="PK679_00605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L39e"
                     /protein_id="HPC54496.1"
                     /translation="MSRSTKGYKVRLAKACEQNRRVPAWVMARTKRQVTTHPRRRNWR
                     RSTLKV"
     gene            complement(115836..116432)
                     /locus_tag="PK679_00610"
     CDS             complement(115836..116432)
                     /locus_tag="PK679_00610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha hydrolase"
                     /protein_id="HPC54497.1"
                     /translation="MKAGVLFSGGKDSSLAAILLSRDYTVELNTYVFGENRDLSAVER
                     AAEALGLPWKVRVFPPGLLSAAVDSILERGYPAEAITMVHKAALHDLASHYRVVADGT
                     RFDDRVPMLSRDEARSLQDTHGCSYVRPLLGYPRREVDRLAGRYLRVILGETGTLENG
                     DYEVELREAVRARGEDATRFFPMFHEQSLVIGPADTRG"
     gene            complement(116429..116770)
                     /locus_tag="PK679_00615"
     CDS             complement(116429..116770)
                     /locus_tag="PK679_00615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HPC54498.1"
                     /translation="MGDDELAELRRRRMAQLQQQAYDQQLLQEEAERQRQIESQIHAV
                     LLRILEPEARERLNTIKLTRPDFARAVEQQLVLLANSGRLTQKITDEQLKSLLQQLLP
                     AKKDFRITRKG"
     gene            complement(116781..117218)
                     /locus_tag="PK679_00620"
     CDS             complement(116781..117218)
                     /locus_tag="PK679_00620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19e"
                     /protein_id="HPC54499.1"
                     /translation="MTTVYDVPADRFIRTLAEELKKKPEMKPPDWAAFAKTGVHKEMP
                     PHDPEWWFVRTASILRRVYIEGPIGVQRLRTIYGGKKDRGSRPKQFRKGSGSILRKAL
                     QQLETAGLIQKEKTGRKVSPGGISFMDNLADKIVREEKAQATQ"
     gene            complement(117341..117577)
                     /locus_tag="PK679_00625"
     CDS             complement(117341..117577)
                     /locus_tag="PK679_00625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HPC54500.1"
                     /translation="MEGSDAMQDLKATVWIGKQGLSESVISEVILQLERRHRVKVKWL
                     RNADFDPQSLARSTRARLVMVRGRTAVLEEHKKG"
     gene            complement(117578..117892)
                     /locus_tag="PK679_00630"
     CDS             complement(117578..117892)
                     /locus_tag="PK679_00630"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030677 - ribonuclease P complex
                     [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component 4"
                     /protein_id="HPC54501.1"
                     /translation="MSRRTAHPEARRIARERIAILFEQARKAFPLDPALADRYVSLAR
                     KISMKHRVRLDREFRRQFCHHCHRFLAPGANARVRIYRGRVTVTCLACHRQMRYPLRR
                     RS"
     gene            complement(117942..118568)
                     /gene="purN"
                     /locus_tag="PK679_00635"
     CDS             complement(117942..118568)
                     /gene="purN"
                     /locus_tag="PK679_00635"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HPC54502.1"
                     /translation="MKRIAALASGRGSNFQAVIDAIRQGSIPAECVGLVSDNPGAYAI
                     TRARSAGIPVFIVDYSRYSTKDEYEADLLRVMKSLHADLFVLAGYMRILGAGIVREFP
                     GKLINIHPALLPSFAGLHAQRQAIEYGVRVSGCTVHFVDEGVDTGPIIVQSCVPVLPG
                     DDEESLSERILKEEHRCLPRAIRAFCEDRIRVSGRRVSIVGEDSAPPA"
     gene            complement(118565..119845)
                     /locus_tag="PK679_00640"
     CDS             complement(118565..119845)
                     /locus_tag="PK679_00640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HPC54503.1"
                     /translation="MIEDFLFLLLFIICLVLSAFFSASEVALISVTRAKVRTLVNEKR
                     PGADVLARLKEDPNRFLITILIGNNIVNVAAASIATAVTISIFGNIGVGIATGAVVIL
                     LLVFGEISPKMYAAKNAEKYALAVARPIYLLSIVFSPLVWVIGRVKRKDSGEEGAAEP
                     SVTEEEIKEWIEVGKEEGAIEQEEREMLYSVLEFGDTTAREIMTPRVDVALIDDESTL
                     EEALHLFNETGFSRIPVYHENMDNIIGVLNVKDVFSSMLSGKKNVSIRDLMYDPFFVP
                     ESKKIDEVLRELQLRKVQMAIVLDEYSSFVGIVTVEDILEELVGDILDEFDREEPQIQ
                     KIGEGVYLVDAKVWVEELNDELDLSLPVSESYESIGGLVIERLGHIPHPGESVYIREC
                     HVTLVVTQMLARRVVKVKIIVHPPGDEKGGEKGE"
     gene            complement(119922..120758)
                     /locus_tag="PK679_00645"
     CDS             complement(119922..120758)
                     /locus_tag="PK679_00645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HPC54504.1"
                     /translation="MVVFAVSTMFFHEYTIGEIMSAVGAAGLDSVEFWVETPAFWLAG
                     QPGDEIKKARDVYPVMERATLHAPILDLNPTSVNPVIAEVSVRFVCDSVRLAAGTGFP
                     LVTVHPGRRTAKRPPGPADCAKFERYIRALEEVSRESGVKVAMENMENRINALVSTPE
                     GMRDLLDREEWLSFTLDLSHAMADGPGVASRYIDLCGDRLVNVHVSAGREGRMHLPPS
                     GDPGVSGVLDRLSRSAYRGHLTLEIEDLALPRPLSYRQKIALLSHESGFMKGFFGEST
                     NL"
     gene            120798..122051
                     /gene="xseA"
                     /locus_tag="PK679_00650"
     CDS             120798..122051
                     /gene="xseA"
                     /locus_tag="PK679_00650"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HPC54505.1"
                     /translation="MTRNSPGCGMDSPGHPPGIFSVSEVSSLIGSLLDDVRLHDIWIR
                     GEVTNYKNHTSGHRYFSLGEKAGERNALISCVIWRTDAARLACELADGMDVIAFGSVG
                     HYSPGGRYQFYVRDIRPAGRGEKYLLIEQWKAQLSAEGCFDIARKRTLPPFPARVGVV
                     TSETGAVLQDIRNVISRRCPVELVVSPTAVQGDLAHIEISRAIGRLAGLVEVIIIARG
                     GGSFEDLFPFNHPDVVRAVASSPVPVVSAIGHEVDVTLADHAADVRAPTPSAAAELVV
                     PERVKILEELGGIRKLLAGRLLAKLDRASADLADFRERLSARRMGQRLTVRREDLSVL
                     ESRMVREMESRIAREKERLAGYSRLLAAGNPVNLLSRGYCIITREKKVVRSIREMSPG
                     DRISIRMADGSAEARVEEVYHDTDV"
     gene            122035..122217
                     /gene="xseB"
                     /locus_tag="PK679_00655"
     CDS             122035..122217
                     /gene="xseB"
                     /locus_tag="PK679_00655"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HPC54506.1"
                     /translation="MTQTFEDLMKEIKEILQKIEDNQTGLDEAIALYERGAVLIRQAE
                     EILAGAEMKITMLGRD"
     gene            complement(122232..122663)
                     /locus_tag="PK679_00660"
     CDS             complement(122232..122663)
                     /locus_tag="PK679_00660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF371 domain-containing protein"
                     /protein_id="HPC54507.1"
                     /translation="MPGVARVTIRCKGHPFVTALHPTTLEITRDTELTPRGDCIIGIA
                     ADMAARDLPREVRELLCRDDAVVTAGFCCEGQVVTVRGRGSSRMTLSHPDDMVFRRSS
                     FVCDRTVAICADGAARTFPRDFVAQVAAGKPVIVTFEVSVP"
     gene            complement(122732..123574)
                     /locus_tag="PK679_00665"
     CDS             complement(122732..123574)
                     /locus_tag="PK679_00665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54508.1"
                     /translation="MVTAALADAVSTILGKPVLWVPGLVVGCLAAMDIVLQYYFGTFF
                     LTRLWVIEALAVPFLVAGAYSEIRNTGEEPQTFWSGGIRYYFRILVPLLVIAFSILAT
                     IVLLAIPLSFLGNSTLVLPYIILGSAVPIAFFTFFFDCAAVFEDCRVFESIRRSVEIV
                     LNRPGQVIVFFLVAAGIVILVSLPLMVIWTGLLYENLVPLASMDQGELQALTMETLNG
                     MLGPGGIGLTALFSCIWFTLAGNILLTFKAVFYRHILGQVPQAGTTVPLRGEYDEKGR
                     WYKY"
     gene            complement(123579..124169)
                     /locus_tag="PK679_00670"
     CDS             complement(123579..124169)
                     /locus_tag="PK679_00670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase alpha/beta domain-containing
                     protein"
                     /protein_id="HPC54509.1"
                     /translation="MSYTKKSVYYFDAPGPQNTWDCAEIALERARELSIRKVIVASTS
                     GKTAEEFFRVLEGTGIRLIVVTHVVGFSKPGEWEFSRETAAKLEKAGVTIVTGTHVLS
                     GLERAFSRSAKVGGGSRTEAVAEAFRRVIAVGLKVAVECTLIAADQGVVSPDEEVIAV
                     GGTASGADTVCVIRPAHTASFFDLQVREIVAMPRER"
     gene            124213..125382
                     /locus_tag="PK679_00675"
     CDS             124213..125382
                     /locus_tag="PK679_00675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HPC54510.1"
                     /translation="MITLALAGKPNCGKSTFFRAATMAPAEIAGYPFTTIDANFGVAY
                     YRTDCPCRGLGLTCGHCTDGIRYVPVNLIDVAGLVPDAHKGKGLGNQFLDNLRQADAI
                     IHIVDASGSSDSEGNPVEAGSHDPLQDVEFVRREMTMWIFGILDKHWQKIQRQAQSKT
                     YSVHRGIADIFTGLKVAPEDVMDAERSAGIDLVHADQAALVRFCEEIVRISKPTLDVG
                     NRVDLAPDGLVERLRAAGLLFATAAGELALRNAVAAGLIRYHPGDPAFSVVRDDALSP
                     AQKAGLRTIAQVMEKFGGTGVQQAINRAIRDLLHMIVVYPVEDEHRFSDSKGRVLPDA
                     FLMREGSTPRDLAYQVHTDIGKGFLYAVDARTNMRVKDTYQMKDGDIIRIVSTAK"
     gene            125466..125786
                     /locus_tag="PK679_00680"
     CDS             125466..125786
                     /locus_tag="PK679_00680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54511.1"
                     /translation="MGGEIYQAQILKNFFDTITGTDRNLTRIFMCVVSLAKIRMEPPE
                     KLAFLIDQLRKSKMHKELSVDILDYMCDVAAQLDITAVQTAFGAKEIGEIAQDFRGIS
                     MDSL"
     gene            complement(125864..126718)
                     /locus_tag="PK679_00685"
     CDS             complement(125864..126718)
                     /locus_tag="PK679_00685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54512.1"
                     /translation="MFSESDRDTRRKELGLVLFILVPVLSFGGLVLGIALVNAGIISD
                     AADFYWGSVAASLVLAFLALIKPRKDIVSLCAPMFALFVFIVPLETKPSLLLQGLYAA
                     SITALAVRLHLRFSTPKISEKEEKSMEKYLYDYIHRITPFFSKVSRDCAHDIASTVLS
                     FKFGLYAKAGTDAGRALSRLGEMENRAVLERALKIVKERAEALDQSLPGGFSAVSFEK
                     EDIPFLALNIPPEQVEDRNVYTLDNALLLLYAVAYLQSPDDGQSLDEHQNFVIQILED
                     YRNLISQK"
     gene            126838..128016
                     /locus_tag="PK679_00690"
     CDS             126838..128016
                     /locus_tag="PK679_00690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NDP-sugar synthase"
                     /protein_id="HPC54513.1"
                     /translation="MKVCIMCGGEGTRLRPLTFERPKPCIPIVGRPSIQHLVSHLSNL
                     GFREVVITLGYMGSAIENALGDGSLFGVDITYVREKTKLGTAGSVKNAQRHLEDGNFL
                     VVGGDHVTDLNLLDFYREHARHRSPVSIGLISIDEPGDYGIAEIDADFRIRRFKEKPS
                     PGEIFSNLASTGIYVCTPAIFDEIPPGTKFDFARDLFPRLMEGGHTLRAYLARGNWTD
                     VGNPASLRQAEKWKLQEIPFTSISGDLTMKAGQIQGPVQIGSSFTMGNGSRVIGPVSI
                     GAGTEIEDHVLIGPYTCIGGNCRIRSHAKVFSSSIYDRVTVGKNSTVSGSIIDNDSVI
                     GDDCSLENDTVIGPRVTMEKGVVVHSRTRVWPEVTVPAGAVIREHLLNEEYEVRCDGS
                     "
     gene            complement(128013..128798)
                     /locus_tag="PK679_00695"
     CDS             complement(128013..128798)
                     /locus_tag="PK679_00695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54514.1"
                     /translation="MDKKKVRDYMTYDVITVSADGTVQEVMDKIRKTGHDGFPVVDGK
                     EVVGYVAARDLLFKPPDTPVRDVMSDKLIVADPDMSINDAARVIFRSGIQKLPVVDEH
                     NHLLGIISNTDVIRSQIEHVSPEKVFNFISTLRTLHGINPELRREVVPIDKLVPTQSR
                     IYEDELEGRIYEIRKGLAEPLIVVRKPGRLILVDGHHRAIAARKLGIKALDAYVIEVN
                     EDIELGMERTAKAMNLRSLDDIQILDYARHPLVAITHRLGRRG"
     gene            complement(128871..129341)
                     /locus_tag="PK679_00700"
     CDS             complement(128871..129341)
                     /locus_tag="PK679_00700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HPC54515.1"
                     /translation="MVFRRRYPFGWMMRDFEDMLTEMENRFWGTGGRFLPAAGVADRF
                     LPAIRGEFRVDVREHDDEIMVVADLPGVDKEDISISLLNPNTLEIACERRSDKEEKDE
                     GYYVRERMYGSMSRTVALPHDVTEKGASATFKNGVLEIRLKKSKEERGSRIKIE"
     gene            129548..130246
                     /locus_tag="PK679_00705"
     CDS             129548..130246
                     /locus_tag="PK679_00705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54516.1"
                     /translation="MKKPKGKEKKAGSGWNLQKIGIIVIGVSFAVIMVVSSLGMSWLI
                     TLNPAAAGDHATVALTLYDEQGRPVLTSDLKKFNQTYEAGNTVWLCGPFSMYVGQTSS
                     KEIVPVPVFNYMYGESRYALFSAEYNAIVQGIAGMKQGETKKIAIPSLGGLEREMSVE
                     QFEGIGGNFTAVVPGDQVILGFAEEPGVTAGTNETPSIVIRTGYVTSKTADGIRVNFA
                     YPTAEVSIRELTKV"
     gene            130287..130571
                     /locus_tag="PK679_00710"
     CDS             130287..130571
                     /locus_tag="PK679_00710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HPC54517.1"
                     /translation="MAIRVLYFFQEGCMACHEQEPILAEVESALGIRAERINPARDRS
                     YIAKYRLSVTPTIVIERDDATEGARFEGLVHREQLEEAIRGISRGTRRPA"
     gene            complement(130543..131130)
                     /locus_tag="PK679_00715"
     CDS             complement(130543..131130)
                     /locus_tag="PK679_00715"
                     /inference="COORDINATES: protein motif:HMM:NF039705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HVO_0476 family zinc finger protein"
                     /protein_id="HPC54518.1"
                     /translation="MQREGDEEYFCPVCSARTDHELVARGRNPVGRCLECGDVHPVVV
                     GERQKTVNVRAIVSDGPSSRICTVEMDDAEVCRTGDTFVAACGDEYTGVEVTSIESKG
                     VRVKQAIAGEISTLWTRKVEEVALRVAIHSGGITTSFHVMVPGEELFCVGEVYTIGKR
                     RFRISRIKIRDGGMLRKPGQKAEAKRIRRVFGYPG"
     gene            complement(131155..132363)
                     /locus_tag="PK679_00720"
     CDS             complement(131155..132363)
                     /locus_tag="PK679_00720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00297 family protein"
                     /protein_id="HPC54519.1"
                     /translation="MLNQMGERLATVLVLSFVLIAPFIQPPWILAVIVLLSSLVMYLI
                     QRTRLLAIALVPIAILFGLSILPLFVFSCTLAILVTGEVIFHDAKDRMLSYILQIISG
                     FFACVLIMFYFNTWAPLVVIFGIVVAVLLKAILRRREDALMIEALGVAMTMFLIDELN
                     YSVDLALIAFAVIIAFSFGFFSYRTRTADVSGLFSGALIGIILIVFADIRWFIVMLAF
                     FILGSASTRYRYDYKQQMGIEQGRGGARGYLNVFANGSVSAASAVLWGVSGSPVFLAL
                     FVGSVATAASDTVASELGVTGGDPYLITTFEKVRPGTNGGVSVRGEAVAMGSALAISL
                     LAWILGIVDLPVAVACALGGFIGTNIDSLVGALMENPGLIGNAGTNFIATLGGGVTSV
                     AIMILFRSAM"
     gene            132531..135125
                     /locus_tag="PK679_00725"
     CDS             132531..135125
                     /locus_tag="PK679_00725"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HPC54520.1"
                     /translation="MSPSLDLPKNYEFSEVERRWQSAWRDENNYFDPASNRPKFIIDT
                     PPPYPTGTFHIGNAFNWCYIDFIARYRRMKGDNVMFPQGWDCHGLPTEVKVEEIHGIT
                     KNDVPREEFRRMCRELTLSNIEKMRRTLRRMGFSVDWSHEYITMLPEYYKKTQLSFLR
                     MLAAGYIYQSEHPVNFCTRCETAIAFAEVAYEPRETTLNYFDFDGLEIATTRPELLAA
                     CVAVAVHPDDDRYRDMAGRRLTVPLFGHSVPLIADPAVDPDFGSGAVMICTFGDKQDV
                     HWWKQHNLDLRKAIDRQGRMTAIAGKYAGMKSGECRKAILEDMKKQQILTRQEPLEQR
                     VGACWRCKTPIEIMSERQWFVKIDPEAIMKAAREIRWVPEHMLLRMENWVSQMEWDWC
                     ISRQRIFATPIPVWFCNACGEMIVPDEDQLPVDPTVDKPSRPCPRCGSTDFSGEEDVL
                     DTWMDSSISVLNVTGWNGKDVSPLFPAELRPQGHDIIRTWAFYTILRSVALTGKRPWD
                     TILINGMVLGEDGYKMSKSRGNVITPEEIVEKHGADALRQWAASGAATGSDIMFNWND
                     VIAASRFQTKLWNIARFVHLQLRRRPYSRDAPPVALADRWLLDCLAGTVEEVTAAMDA
                     YQFDRALKLIREFAWDVLADHYIELVKGRLYADDPSRDGACRVLETAIDTLCRLMAPF
                     TPFFAEECYSYLGRGSVHAQEWPGLLPRDPDARRKGDILVNVVAELRRYKHEQGLALN
                     APMGRVTIFSAPFSDDSNDASRTLNAPVEWHTEPPRLEKVPGDVQFNMAVIGPALRKD
                     AGAFMKAVRALPQDLLLNPPEKIDIGGKEIPVPKDSFSVQFTYRLGGEKVDVRVVGDV
                     IATIHASP"
     gene            complement(135079..135702)
                     /gene="tmk"
                     /locus_tag="PK679_00730"
     CDS             complement(135079..135702)
                     /gene="tmk"
                     /locus_tag="PK679_00730"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HPC54521.1"
                     /translation="MVLITLEGIDGTGKSTLLSALEDSLSDLSPVFTREPGATWIGGQ
                     VRRAIAERADPVTEALLFAADHASHLSSIVRPALAEGRLVISDRYTDSRYAYQSVTLE
                     GIIPDPLGWLRAVHDGWTIPPDRTVLLVLPVAEALRRKAGAAVPEHFEEATLLERVQK
                     NYLRFAEEEPSRFLIVDAGRPAHEVHSLVAAAIRDWHGSLRSRRQRP"
     gene            complement(135693..136364)
                     /locus_tag="PK679_00735"
     CDS             complement(135693..136364)
                     /locus_tag="PK679_00735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HisA/HisF-related TIM barrel protein"
                     /protein_id="HPC54522.1"
                     /translation="MDLILAMDLKGGVVVHGSSGNRRTYMPLTWGLSPTAEPAGYVRA
                     VSPRAIYVADLDRIMRTGDNTAEVLSCSREVSRCLLDRGAAGPSDFLHHPRITDIAST
                     ESSEVDFALYPGGLLSVDIRDGKVISSGQDPLDVLSRAESWNFSGAIVLDVGAVGTGK
                     GPDLPLLGRLRGAYGRELLCGGGISGEEDLDALAALGYDGAIVSTALHRGRIPPDAVR
                     RGTWS"
     gene            136408..137094
                     /locus_tag="PK679_00740"
     CDS             136408..137094
                     /locus_tag="PK679_00740"
                     /EC_number="4.2.3.153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(5-formylfuran-3-yl)methyl phosphate synthase"
                     /protein_id="HPC54523.1"
                     /translation="MQLLVSPRDIEEAKRSLAADIIDVKKPSEGSLGANFPWVIRSIR
                     KLSPKPVSAAIGDFDFRPGGAALAAYGAACAGADYIKVGLMFDGASRAEELIRAVVRA
                     VKDEFPEKKVVIASYSDWARLGSISPSDMAPLAARAGADVAMVDTGIKDGRSTLEFMS
                     EQELRDFCKLNRDNGIGTAIAGSLTFDDLPVIRKISPDIIGVRGMVCGGDRDSGIREE
                     LVEKLARMVH"
     gene            137098..138564
                     /gene="guaB"
                     /locus_tag="PK679_00745"
     CDS             137098..138564
                     /gene="guaB"
                     /locus_tag="PK679_00745"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HPC54524.1"
                     /translation="MFSEKLNAPLALTFDDVLLVPASSLVEPNEADIRTRFSRNIPMN
                     IPLVSAAMDTVTESAMAIALAREGGIGVIHRNMSAEQEVAEVRRVKESEQLIERKVLS
                     VDPETSVAEVERLMVEHGIGGVPVVEAGKIVGIVSRRDVRAIATRRGNESVRAIMTRD
                     PITARENISMEQALETMYTNKVERLPVVDSEGHLIGIITMQDVLEKRQYPNATRDSQK
                     RLRVAAAVGPFDFERAVRLDECGADALVVDCAHGHNQNVVKSIRDIKGSVKADVIAGN
                     IATAAAAEDLVDTVDGLKVGIGPGSICTTRIVAGVGIPQVTAIASVADVIRETGVPLI
                     ADGGIRFSGDVAKAIAAGADSVMIGSLFAGTDESPGRIITMKGRRYKQYRGMGSLGVM
                     SGGVSSDRYFQKKEIGKTKFVPEGVEGVTPYVGSVSEVVYQLVGGLKAAMGYTGSHTI
                     SDMHEKTRFVRITAAGHTESHPHNIMITDEAPNYRLTD"
     gene            complement(138667..138987)
                     /locus_tag="PK679_00750"
     CDS             complement(138667..138987)
                     /locus_tag="PK679_00750"
                     /inference="COORDINATES: protein motif:HMM:NF039183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5658 family protein"
                     /protein_id="HPC54525.1"
                     /translation="MQKAYQIMIGALFALLGGLLVLDVLLTTIILRLGGFEMNPVMAW
                     IVQNPCLHLGVKCAFAGFIIYVAGRAEEMKEYSGAIILMAVCAFFMVVFVHNLAIFMG
                     IFFS"
     gene            139201..139821
                     /locus_tag="PK679_00755"
     CDS             139201..139821
                     /locus_tag="PK679_00755"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HPC54526.1"
                     /translation="MLDQVEIARILDILGNRNRRRIIDLLRQKPCFVTEISDRLMLSP
                     KAVIEHLQIMEREEILSFRMDERRRKYYYLANDIDVMIRLLKREQLQTATRDESNRLR
                     SALFQLRRMIELREELAEKLKNTEQAIDGQIRDITNLAQAALDNPLQTDILISLAHCD
                     LTLDDLCELTEAPRDAVSDNLEILGKKHMIEQAGETFRLRDTHAGF"
     gene            139859..140245
                     /locus_tag="PK679_00760"
     CDS             139859..140245
                     /locus_tag="PK679_00760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54527.1"
                     /translation="MVEELLRNLPQEENARIIGCTIITNGGSPHFTRNPNSRSEENDI
                     PIEIIDSPDMLFVTARLPSTLHTAPYADITGESLHIVVNERRIPVPVSCRIDVIHSFY
                     QVRHGVLDIILKKKKVPPRSTPAESG"
     gene            complement(140396..141199)
                     /locus_tag="PK679_00765"
     CDS             complement(140396..141199)
                     /locus_tag="PK679_00765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HPC54528.1"
                     /translation="MEPLVAAAVLVGTGGTAGFASGLFGIGGGFLMTPVLYWLFSTGG
                     IGDTEATRLAFGTSLAVIIPTMVSGTAGHHRREAVDWKAAVPLAAGAVLGGLFGGTVA
                     SYLPGTTLRTIFAVLVITMAIRMAWSSQSSPENRKNGSGPAFAVLGFFIGTVSGLAGI
                     GGGVLLVPLLVILFGFPVHSAIGTSSACLVFSSGAAVIAYIIHGLSAPGLPPLSLGYV
                     YLPAWAALVVTTVPLSRIGVRFSHTCTPGFLQGLLAVLMVAIGLSMLVA"
     gene            141274..141861
                     /locus_tag="PK679_00770"
     CDS             141274..141861
                     /locus_tag="PK679_00770"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HPC54529.1"
                     /translation="MGLSALLIIDMQNDFVREGSPLRVAGAGEIIPRIREVLDAFRER
                     HLPVIHVLRVHRSDGSDVEVFRRELFRRRAFAVRGSWGAAVIDELSPAPGEYTIEKTR
                     MSAFTGTDLDLLLRSLGVTRLFVTGIQTPNCVRTTVFDAAACNYEVFLVTDAVAAQSA
                     EVHAANVRDMENIGTRIIRAAEVPRILDTPVPIDP"
     gene            complement(141931..144114)
                     /gene="nrdD"
                     /locus_tag="PK679_00775"
     CDS             complement(141931..144114)
                     /gene="nrdD"
                     /locus_tag="PK679_00775"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HPC54530.1"
                     /translation="MPRRDTRQSTLDGVFVAPMPPVRTTDGHILEWDRERIVRQIVEE
                     TKLVSTFYGYESASEETAREIARLVEERIKSMNLQTLSGPLIREIVNITLLEKGMVQY
                     RNVCTRVGTPVYDAHQIDVGRGFEARDNANLQENAETSHKKKADKISKEQYLLQLPPH
                     LADHHLSGNIHIHDLEYFGTRPFCQDWDLRYFFYYGLMPDGNGTKASVAGPAKRAEVA
                     VLHAVKALGSAQTNFAGGQGYYNFLTFLAPYFEGMAYDEIKQLMQMFVYEMTQMMVAR
                     GGQLVFSSVQLSPGVPSLWKDKPCVYRGMVWDGTRGPRRTYGEFEREVRLLFKALMEV
                     MLEGDAWGKPFSFPKPEISIEPDFMQEDEAFNDAHPDLPTYRDLYLLTFELASKFGTP
                     YYDNQIPAYRGAGKGISCYQCCAYQFSAIADQDSQFEDKLYFRDGKHFSMGSWQVVSL
                     NCPRAAYRAGGDNEKLFAELRALMDVCVEVFRIKRRWLETIRAQGRMPFAMQRPRDPH
                     TGERGAVAVDLDGLVYTIGVVGVNEMVQHHTGAQMHESREAFSLAVLAMTKMEFYAKE
                     LSERHKMTIALARTPAETTGQRFAVADLLNSEFRDHAKRVIKGDLEKAQRDLGKTRDL
                     PIYYTNGTHVAPGANITMAERIAIEHVFFPIVDGGNIFHIWLGESRPDPRGLMEMALN
                     LCRTTQIGYFAFTRDLTVSLHQFREHEGERGRISGWVATGPGVRA"
BASE COUNT        29891 a        42723 c        42608 g        28763 t
ORIGIN      
        1 gatcatcatg aaatacctct caaatgcttg attaatttca atcctatttt agtccgattc
       61 aaactgcccg acatccgagg tgtctcgata cctcgatacc gatttcaatc ctattttagt
      121 ccgattcaaa cgttgccggg ctgctggggg ggacccatgt ctatatattt caatcctatt
      181 ttagtccgat tcaaacagcg cccaaaaatg ggtattttga ggttatatgc aagctcaagt
      241 aatcatagta gatgtatgtg tcggggatgt tagataatgt attcgattta taaagataca
      301 cgagataaat cagataatag tacaagtatc agccttttcg acaccgagtt ttattatttt
      361 cacttgatcc tgcgttcgaa aagtgtaaaa tctcacggaa tcacttttac tatcaataat
      421 agtcttcaga ccatgtgtaa tctctgcaaa ttgtttctcc gtaatatcac cttcgaatac
      481 agaattctgt acccaattta gatatcgcct tagaaaatta catgccttgg agaccctccc
      541 caccgcaata tcgtaaacga cgataatgta cacattacca ccatatgaca aatggttcgt
      601 atttcttgag gccaagcagg tgtttacaga gcttgagaca ttccagatag ggaagtcttc
      661 cgtatgacac atttcttttt aaacttcgat gtttgattgt cgtttccatt ttattattaa
      721 actctgcgat aaagagcctc cgaccactat cattcataag gcaagattgc agatctttct
      781 caaaatcttt atccgagatc atttttttat tgacgagttt gaagattgtc cgatccacaa
      841 agagaggttt aaatatttca gcaatatcga gtgcaagcga aaatcgccgt tcagatggtt
      901 catggagaaa ggagatggtt tgatcaagtt gtgtgtggta gattgcattg attactatac
      961 catacatcag cgaattaccg aaactaatca ttgcattcac cggattttgg ggcggtcgac
     1021 gacttctgct ctcaaatgaa aaattacttg tgagaatgct atcgaaaacc gaataataag
     1081 cattgcggat ttttccttcc attgccatga gttccggaat agtctgacac acgggcacgg
     1141 tttctaatga tgattgaatc gttttaataa cctgggagag atttttttcc tgattgtgat
     1201 agtactcgag gttcttgagc atattctgtg cagcaccaga aacaaatgat cgtgcgatga
     1261 acaatcgttt ttcgggatcg caataatgtt gaccctgtcg taaatgcatt tccccggaaa
     1321 ggagagattc tttggggaga agcgtacttt cgtattgacc gtaatatcca aagaaatgaa
     1381 caggaattgc atttttggca agaaaagaga cgacaccgga ggtaatagat actctcccgt
     1441 atgcaaaaat cgctccgatt tgttccaccg gcagagctct tttttcgtat ccctccctgt
     1501 ctgaaacatc tgggacctcg gggttgtgtt cttcaccatc gaattcttca atgaaatcgg
     1561 gatcttcaca ttgtgctgtg aacgcagtat tagcgtcgtt ttttctactg atgaagtaga
     1621 cagtattttg tttcctgacg atttttccat tcttgagaat gtaaaaattt tgtttcatgt
     1681 tttacaccca gcatagttca aaatatgcac attttctaca gtacggtttc tctatgggag
     1741 gaggtgactg gggttgtttt acaatctcat tgacttcaag aagtatcctt tcgatctctt
     1801 tcttcacttc gtctgtgagc atgagtcgct cgcgcttgcg aatcaaaggg tagtccaaaa
     1861 gtccatcgac attaggaatg tcgagtatct cctgcaggta gtaaatataa taatataatt
     1921 ggtaccgatg tgcctgttcg agtttctttg atttctttat ctcatggata gtaattcctt
     1981 cacctttttt aaaaaaatct attccaattc gatccataat tatattttta ttttcccgtg
     2041 agtatgaaga ctcatggaca aactttccca ttccaaccag ttctgaagat gattcttgtg
     2101 aaatgttatg ggaaaatagc cagagctttg tgggacacac gaagtaatag ttgatttgag
     2161 taccggttaa ctggaccctg gacagctgtt taatcataat agtaagaaaa atacgattaa
     2221 ttaattatat ataccggtat tatgattatt tgatctccaa cggagtattc atggttgaat
     2281 gatattggaa agcatctcaa aaccaaaatc acaaacaaaa agaaagaatg gagatccgtt
     2341 tgtcgaaata ggtattctgg caattgagct gataacaaag aaaaattttg aaacttgcac
     2401 gacacaggac ctccagcgtg ccgctgacac attgattgaa atttttttaa cgccggcatg
     2461 gaaaaaagaa cttatctcga tatttcccaa tagtacgtat attcagacaa gtaggggata
     2521 caaccacaga gaacgttcaa gggaattcct ctatagtctc atagaaggga tcagtccttc
     2581 atcagaatca aaaacatact gttgcttctg tggtgcacag gcttacgaga aaatgcgatt
     2641 ttacaaaacc caaatacctc taatcggatc aggcaaattt gcaaattatt tcccctcatt
     2701 tcaaaatggt ctaaatattt gtgcaaagtg cgcacttgcc atccagtttg ctccattatt
     2761 atgctacaag gcaggcggaa agccctgcct cataagttcg aataacaggg aactcctaag
     2821 ggaatttggg aaggacattt gcaaaacgat caagacccgg ctggcatcag gagaatataa
     2881 ttctcaagaa aattctggat tgtttgatga aaagttcaaa tccccccaaa atgctctttt
     2941 ccatcttgca tataaattcg ggagggaata ttgtgccagg gggatttgta gtaataacga
     3001 gtcaattgta ctttaccaca ttgataatta caaccagggg ccagcagggg ttcgtatcta
     3061 ctcattaccg agcaatatct tcaaatttgt ttcattcatg atgaacagcc ccgattaccg
     3121 atctgcatgg ttctcgcttc tcgcccggta ttatcccaaa tcaactgacg aggaggacct
     3181 tcccatatgg aagacgaaga taaatcccat tcatacctat ctcctggaag gaaaaaacat
     3241 tctctgggca ttcaaagacg atcgaacccg gacagttaca atgccttggc ccgttgtcga
     3301 aggatatatg aggagtgtga gattgatgaa tcaacaaaga attgaaaaaa ttagggaatt
     3361 cagtgacaaa atcgctttga gtataaggga atcgaaaaag ttcagcagag tgcacgatat
     3421 tgcgaatgcc cgtgacctgc catcattccg aaatcaatta aatttgatag tgaaggattg
     3481 gcagaaacta ggaaaaggag agcccattat cacatttgac gattacatta ggatcttgat
     3541 cccaggggat tatcgcggat ggacagaagt ccgtgatctg attgttattc gcctttacga
     3601 gaagctgcat gacatccttg taaaagaaga tgaaaattcg gaagtgacag aatgaagaca
     3661 attgttggag cgtatctgat tgatgcccca ttttccgctc tcaataacag agggatcgat
     3721 agcagggcag caaacgaaaa tgaagtggca accaagacaa tcaactcacc cgaaggtcca
     3781 cgaccgtacg tctcagcaca ggctcttagg tattggtgga gacagatcct gaagaacaaa
     3841 tttggctgga attgctcacc cgtcgaaaaa atcggatcaa atcaggcaat tacggccgca
     3901 gacccgatag aataccctga tgatgatata tttggctata tgagcgcccg gaagatcgaa
     3961 gtagaaggaa aaaagaaacc tgaaaacatc acagtaacca gggtatctcc cttaaagtgc
     4021 tcccctctta ttggttatcc cattcgcgtc acctccgatt tcggtgtaat gaacagggat
     4081 ttcgagggag acccggtcct cttcaatcat caattttata gcaacatcct caaaggcatc
     4141 tttgcccttg atctggatgc agccggtaca tttactgcca ttaataaacc cggaagcatg
     4201 aacctttccc cggacctggt aaaaagatgt gaagaagcgg gatattcagg tagaaatgat
     4261 aacaagaaat attcactacc tctggatatg aaagtaaaac gagtaacaga taccattgcc
     4321 gctctcaaat atctcaacgg cggggcaatg caaacactgc atcataccga cgtctcgccg
     4381 aagtttatca tcctcacagc attgaggggc ggaaacaata tcttcatggg ggtattaccc
     4441 caccggaatt atgaagaagg actggtcaat ctggatgctt taaccactgt gctggaagat
     4501 tacagaaatg acctcctgac tggtgtttat atcggtctat tacctggatt tggaacagat
     4561 aatgagaaag aattgatgca gttcaaggcc ccggaaggag tgcgacttga gatcaattct
     4621 ccagttaggg ccattgatgg attcataaag gagatttcgg gtaaaagtgc tctatttgag
     4681 gcatagggat gaaagtcctc cgtgctcgga tacgtgcaat gacggcatcg ttccggtacc
     4741 cgatgttcat ggttgcgtac caaccgacat acagtgttcc ccccatttca acggtttacg
     4801 gacttttgtc cgctgcaaaa ggaaaaaaag tgcatttaca cgatataaaa gtgggatacg
     4861 atttcgtttc tgaggggaag ggtgtggacc ttgaacggat ccatgtctat ggtggtgaaa
     4921 cgagagccca tcttggcacg gatattgtaa acagggaatt tttatacaat tgttgtttga
     4981 cattgtatct ctctgatatt tcattcgagg agtatctcaa gtaccctcgt tattccctcc
     5041 tcctcggacg gcagtccgat cttgcctttg ttgaatccgt agatactgta gaactcattg
     5101 aaaaagaaaa aatcgagatt aaaaatacaa ttattccatt taatggtgaa attccggggc
     5161 agattgtttc ccttccctct gattttactg atgaggcaga aagaaaaccg ttgaatgtta
     5221 tgtcatattg tatcgtagat acaccccaga tagtcgaaaa aggatatttc gatccagata
     5281 ggcaaactgg cgttttccta catgaattct gaattatggg caaaatcaga tggagagagc
     5341 ctgtgggatc ataccctctc ctgccttgat gtcttcttat ctctccgtga tattttcccc
     5401 gatatcgata aaaaaacaaa ctatatgaat ttttacaccg atgtcttcaa tgcactcttt
     5461 tttcatgatt ttggaaaggc cgcaacaggt tttcaggatc agctaagagg tggcaatcga
     5521 tggcattaca gacatgagat cctctctgtt ccatttgtcg atgcactctc ctcaggagat
     5581 accgatatta tcaaactgct cattcttacc catcacaggg attgccggga acttatcccg
     5641 tacatcacac aggatgatga tccagtctcc tccccgtcat ttcaggatcg ggtctctgaa
     5701 gtgaaaccga atatcgagga gttaaaacaa ttaatgagaa tatatccaca gatcgcacga
     5761 aaatatctgg gacaggatac gagcataaga cccattgatt taaatggata ttcggcagat
     5821 tgctgggaaa aaatcattaa aactacctca cagtgtctca atgatgaaat atgcaggaaa
     5881 agactgaaat ttattggcat atttggtaaa ggatttgtca ccagttgcga tcaccttgca
     5941 tcaggaggaa ttaaaaaggt actaaaaccc ctctcatcac tcgatgatgt attcagatat
     6001 tctacatata ccagtattca gaaaaaatgt cgtgatatta agggagatgc actgataatc
     6061 tctcccacag gttcaggaaa gacggaagca gccctctttt gggctactgc aaatctcgat
     6121 tccttgcggg gaaacaggat tttttactca ttaccataca cagcaagcat taacgccatg
     6181 tataaaagaa tattgaagcg cattggtcct tggtataatg atgaagggtg cgtatcgctc
     6241 ctccacggaa gggcatcata ttacctctct cggatgtatg aaaatggaaa tggatttgga
     6301 ttccataaag atattgcaag gaaaatttac agtccttata aggtaatgac accgttccag
     6361 ttattaaaac atctcttttc aataaaagga tatgaaatgg ggttacttga aatgtaccgc
     6421 gggattttta tcctggacga aattcactct tataacgcac aaacggttgg tctcatcctg
     6481 tcaatgtgtg aatttttaaa aagtgaatta gaggcaaaaa ttcttttaat gtcagcaact
     6541 ttaccagaat tcattagaaa atgctttacc gattctcttg gaattaaatc cattctgaca
     6601 atggacaagg atgaacttga tcattatacg cggcataaat gttccctgtt agatggaaat
     6661 atcactgatt acatagattg tatttcggac agaatcaatg ctggtgaaaa agtacttatt
     6721 gtatgcaata ccgttaaaca ggcacaaaaa atttacaata ttttcagaaa tgagacaata
     6781 aattcagctt tacttcattc caaattcatt ctgcgagaca gagaacagat tgaacgggat
     6841 atttcatcgc tcaatatgct tgttggaaca caggcaatcg aagtatcact cgatattgat
     6901 tacgatgttt gttttagcga accggctccc attgatgcat tgattcaaag attcggtcgt
     6961 gttaatcgaa aacgaaaaaa aggaatatgt gatgtttttg tctttactca tgggtcagaa
     7021 caggattcat tcatctatga taaagaaatc gtaaataata cccttgatga actttcgaat
     7081 attgaccttc tctatgaatg gctcatacaa gcaacggtgg ataaaatata cagagatggt
     7141 tttgggaaaa gagaaaaaga attcagagat attagacata ttttttctca ggttattgat
     7201 gaaatcgtcc catttgaaaa tgccgatcgg agtgagtcgg atttttatcg gttatttaat
     7261 tcgatagaag ctgttccgga ggcattcagg actgactatc ttaaatgtat taaagctggc
     7321 gatgtataca gtgcaatgca atacactctc cccctcggcg caagtcaata tcatagattg
     7381 aaacgcgaga acaggatatc tacaaatgag gggatgttat ttgtaaatgc caaatatgat
     7441 cctaaactcg gattgctgat tgaacaacgc gatccagggg cttttacagt atagttgggc
     7501 gtgaattttt ttctgaataa actaaattta caaaaccaaa accataacta ttacgttcac
     7561 caaatcctgt atccatccca aatcgaacaa ttttcttttg caataaatcc atatgattcc
     7621 aggaaaactc ccagaggctt gctgcgacac cataactttt tccatcgata attattcgtg
     7681 tgtgcacagt cttcttgaaa ataaaccttt caaagagatt gttatgtgca acttccgttc
     7741 cgtaatattc gttatatttt tttattagat tttcagagag ctgtttcaca aatgcctcaa
     7801 atgatacaga aggacgccaa tagatatagc ggggttttcg ctcattttcc ggcacaccat
     7861 agagatcata attccgctcc ggaatgcgga gaatgatagg tgtagcacaa acaattttga
     7921 caggaggaga aggtagtgaa acggctattc tccgacaatc ttggatagaa aaggaacaat
     7981 cacctatatg aatagaggat cccatttttg caaaaatctg ttttccgaga ccatcaatca
     8041 aatgtgtgct cggtgaagat atgataaaat tccgactatc tccctctttc atatcgccat
     8101 atggaaaaac gttcgagaaa caaaaatatt tatatccttc tttatcatga atgccaggat
     8161 atcccccttc ctgaaacatc cgatagatga acccttgtat tttatgataa tccagagata
     8221 tgtctttttg atccgcctcg gctttgagag ttaaaagcag tctcataaat tatccttatt
     8281 tcttatttta gaaatttgta ccttcttcga cattggcaag cagtgatcag acttgggcca
     8341 attttcttgg atcaaataac gtattctatc atagcagcgg gcatagtgaa aaccttgctg
     8401 ctggatattc ttcgtggacc gcgggaattg atggatggtg atctgaaaag tctcatttca
     8461 tctatgccca ttcggaaata gtgcgagtta taacggaaat gggaaagatg ttggtcatta
     8521 tactcaaatt atttggaaaa ctactactca atgtggttgc ggaagtgcac ctcatccagc
     8581 gtatggaacg gtatatgtat gccattacgc tccggcagga caggagggca gatgcctccg
     8641 ggatagcggt tcttgttttt atggtcgcct gcttgtaaaa tgaatccaag gatgccttga
     8701 atgacgttga agaagatggc ggccttgtta ttattggaag cccctctgca agagcaaaat
     8761 ttttgctcct tttcactaaa aaagcccgaa aaaccccatc ttcccgaaat attgatgacc
     8821 gtaacggggt actccgggag tgataccaga catggggatg cgaatcagat acgtacttct
     8881 tccccccctt cacccctccg cccggcacac cttcgcaaat atcctcccga gcggcgagag
     8941 cgagaacatc acctgcttcc cggctctctc cttcgtgaca aaacccatct cctcgatctt
     9001 tttgaggtgg tggaacaggc ggctcctctc ctttgccaac tcgtccggga cctccctggc
     9061 ccgggggttt gcctgcagga tgaggtcctc gaggtaaccg ctgctctttg cgatggcccc
     9121 gaggagctcg gcctggtcct tgcgggggaa ctggaccggg atggtgggca gctcgatgat
     9181 ctcctcgatg ccgacctcgc ggttctcctc gtcgtaccgg gggatggacg tgatcatcgg
     9241 ggactgggtg aggcagccgg cgatgtaggc ggcaatcgcg taggtgcgca gcgagccgct
     9301 catgttgagg atgcaccggc ggccgtcctt tcgctccgag aggatgatgt cgatgacctg
     9361 ggaggcagcg ttcatgacgt tgcgcttgtc caccttcgcg atggcgacct cgtacacggg
     9421 ggagaggtcg gacttcacgc gggtggcgac cttccgggag atgcgctcgc cggtggtatc
     9481 gtcgtccccg atgacgagga cgacgcgggt gatcgggtat ttccggtact gggtgatcga
     9541 ttcaatcagc cgttccctgt ggtggccgac gaagacgatg tgggtatagg tcattatatg
     9601 tgggattatt tttctttacg taataaaatt ttttatgtga aaataaaatt ttttaatctc
     9661 ccatcgcatc cccaaaaaat tttttcgtgg tcaatgggaa caaaaaatac acgcagaagg
     9721 cacttggtgc attgacaaaa ttgtaaatta tttttcatga ataaaaaaat tttttacttt
     9781 tgaagtcgaa tattaatcat ggcaggattg gcgggcaggc ccccgggtct cccgcaccgg
     9841 accaccagag gacaggggac aaaaagcaag cggtgtcccg ccacgggcag gatcttcccg
     9901 ggataacgac gcccgggatg gatcgcccgg gcactttttt acggggcaaa ccctgccact
     9961 tccctgtcac caggggcaaa gcggccgccg gggtaaaaag gctgcgaccg gtcacccggt
    10021 tgcaccaccg gtcccggacc tcttcgcgga gggcgggacg cggaaagcag accatccccc
    10081 ccggcggtcc cctctccact cctttctccg cagggccggg agtggcaggg agcattcttc
    10141 ttcaaggaac cggccccgca caaaaagaga caaccccaaa aaacctaccc cggcagcatt
    10201 ccgcaggaaa cgcaccggga aacaggaaaa acaggtggta atgattggac acggctcttg
    10261 aatcatgtct tacatcgctg cgtttcgaag gtggcaccat ccacgggcgg atggaagtca
    10321 tcccgctctt ttccgggacg cacaggggcg gcgactacct cacgctcgcc caggcactcg
    10381 cccagaaccg cctcgtcatc acggaagtgg gagaatcggg gaccgtcccc gaactgatgg
    10441 tcaggaacag gggaaagatc cctgtcctcc tcatcgacgg cgaggaactc gcaggtgcaa
    10501 agcagaacag ggtcctcaac accacgatca tcgtccccgg cgaatcggag atcgtcatcc
    10561 cggtcagctg caccgagcac gggcgctggt cgtacacgtc ccccgtcttc catgactccg
    10621 aggtcatgat ggactacagg ctacggagca aaaagatggc atcggtcgca atgtcccgca
    10681 agttccgggg gacccttgcc tccgaccagc tcgaaatctg ggacgacatc ggggagatgg
    10741 caaggaaggc aaaggtccac tcgcggaccg gggccatgaa agacatcttc tctgcccggg
    10801 aaaaggcaat ggacgagtac atgcatgcat tcccgctcca gcccggccag caggggatac
    10861 tcgtgtacat ggacgaccag ccggcgggaa tggagttcct ctcccgtccg gaatcctacg
    10921 cccggatcca cgaaaagctc ctccgcagct acgtgctcga agcgctcatc gacgacgagg
    10981 cgccgcccgc ccgggcagcc ggggcagaga ggccggcaga gttcatccag agggtcctgt
    11041 tcgcacacga cgaggcatac ccgggcgtcg ggctcggcac cgagcaccgg ctggaaggcc
    11101 ctgacctcgt cgggtcggca ctcgtccacg agggactcgt cgtccacctc gcctgcttca
    11161 cgggcacgtc aaccggatcc tgccgcgcag aaacgcggat ggcaggcttc cgggcccggc
    11221 atgggtcccg tgcatcgggg gcgggaggaa tcccccgcaa cgaaaaaggc aggaacaggg
    11281 aaggagaggg tatctatgaa tcgtgacaca aagcaggcag tctggccatg gcggggagtg
    11341 cggggcaggg acccggctct tcccctcacc ggcagggacc ggtgcatcat cgtcgaggag
    11401 atcggaaaga tgcgggacat cccgttcggg gcagcggtgg aactgctcga ccaggtcctg
    11461 tccggcgcca tcttttccgg cggcggaaaa gagccccgga gggaaccccc gtacgctgaa
    11521 tacctgggga ggctgatgta ccaggtcgca gcccggcagg accttgcgca ggaggatcgc
    11581 cggctgctca tgtacaggat cgcttccatc gggtcggagg aagaccgtgc ccggactgcc
    11641 cccaacccgg tgcaggggtt ctttgcccgg ctcagggcac cggaccgcgg tcaggacacc
    11701 gggaccggga aagaggaaga cacactcccc ctgcccaggg acctcatggt caggctcatc
    11761 aacggggaca aggaggcgtt ccgggccctg ctcggcgagg acatggaaag gaaccttgcc
    11821 ttcgacgagc cgggcagcag cggaaaggac cccctgcgca aaggaatgga aaatgatatc
    11881 gcgggcgggg acgagactgg tccgggaaaa aaggtgcgcc cgaagttaac attcgaaatg
    11941 tggacgctgg agggcgacga ggtgaagatc acgccgctcc attccgggga ggatgaagag
    12001 gaatgacctt tctcacggtc cttgacggtg cacagggtat cgggggaaac aagatccatg
    12061 tcgaggagaa ggggaaggga ctcttcctcg atttcgggaa gaacttcggg aaatacggga
    12121 tgtacttcga ggagttcctg aagaaccggg acctccgcgg tatccatgac ctcatgtacc
    12181 tcgggctcat cccgaagttg aacatctacc gcaaggacct cgtcccctcc gacctgcggg
    12241 tggactcctt cccggccccg gatgtcgccg cggtcctcgt cagccacgcc cacgtcgacc
    12301 acaccggcaa catcgggctc ctcgacctcg gcatcccggt cgtggcatcg cccctctcgc
    12361 ttgccatcat gaaggggatg caggactcgg gcgtctcctc ggtcgatacc gaaacctcct
    12421 acgcatcgcc aagactcccc ctcgacgagt cggggctcat gctgcgggcg gacaagaaaa
    12481 tcccccatac gtgccgggag agcatctgca ccacccgccc ccgggacgaa ctcgttgcat
    12541 tcctctcctc ccggcccggg caggagggtc cgggtgcaaa gaagttcgag ccggccccct
    12601 gccgctccct cgacaacgtc gccctcccgt tcgcggtcac gccgtacgag gtggaccact
    12661 cgatcgtcgg ggcgaccgcg tacatcctca ggggcgacac gacgatcgcc tacacgggcg
    12721 acatccggct ccacggcagg ctcggggaga agacccggga cttcgtccac catgcaaaag
    12781 acgcatccgt cctcatcatt gaggggaccc gtgcagggcc gcgcgaacgc tccgcggcag
    12841 taacgagcga acagacggtg tacgagacct gccttgcgga tgccgaagac caggagggtc
    12901 tcatcatcgc ggacttttcg ccgcggaact tcgagcggat ggacactttt tcccggatag
    12961 cgcaggagac cgggcgtacc ctcgtcgtga ccgcaaagga cctctacctc ctccatgcac
    13021 tcgggtgcgc ggacggcacc tgcaggtacc agggactcgg cgtctacgcg gagctggccg
    13081 atatccggaa gcggaaatgg gagaccgagg tcgtgatggg aaaggcgtcg caccagtaca
    13141 tatcgcacaa ggaactgcgc aattacccgg aggagtatat cgcctgcttc tccttcttcg
    13201 acatcaggca cctcctcgac atcaggccgg agagcggact ctacatctac tcggcctgcg
    13261 aggcattctc cgaggagatg gagatcgact tccggaggct ctggcagtgg atccgccggt
    13321 tcggcctcga ggcacggggg tttgcgatca gggacgacgg gtcgcctgag ttcgattccc
    13381 ggtaccatgc atcgggccat gcctctgcag acgacctcgc gtggatcatc gaccaggctg
    13441 accccgacgt gctcgtcccg gtccacaccg aaaaccaccg gtggtttgcc gaaaacttcg
    13501 ggggcgtccg gatcgtgcag gacggggaac ggctgacgat ctgaccatga tgccaccggc
    13561 ggcgggtgcc ccgcaggact ggttccggac acctccgccc cgcgggcctg aatccctctt
    13621 tttttgcccg gtcgagccgg gtcccgtgtc cggtgagtca aggtacataa cggatcacgg
    13681 gtaaccctag agctgatgcc tgtcaccgtg caggacgcaa gcgacacgac tgctccctcc
    13741 tccctcaaag cgagggtcta ctccatgctc gaaggggacc ctgaatcagg gggacgggcc
    13801 gcatgggcaa tcgacctctt cctgatgctc cttatcatcg caaacgttgc agcaaccgtg
    13861 ctcgagtcgg ttcaaagcat tgcggatgca taccctgcct tcttttccgg cttcgaggtc
    13921 ttctcggtag ccgtcttttc cattgaatac gtccttcggc tctgggtctg cacggagaac
    13981 cctgcctttg cagcggcagt cggggggagg ctgaagtatg ctgcaacacc gcttgccatc
    14041 gtggatctct tcgccgtcct gccgttctac gtcccgttcc tcatcccggt ggacctccgg
    14101 ttcatgcgtg tcctgcgcct gatgcggatc ttccggctgc tcaagctggg ccgccattcc
    14161 tcggccctga agttcgtcag gaacgccttt ctcaaggaga aggaggccct gacaatcgcg
    14221 gcattcgtgc tcgtcatcct cgtcgttttc tcttcgtgcc tgatgttcta cctcgagcac
    14281 gatgcccagc cggaggcctt tacgagcatc ccgcaaacga tgtggtgggc ggtcgagacc
    14341 ctgacaacgg tcgggtacgg cgacatcatc ccggtcacgc cggcaggaaa ggtcctcggg
    14401 tcgttcatcg ccgtcctcgg gatcgcgatg ttcgctgtcc cgaccgggat ccttgcagct
    14461 gcgttcctcg aggaggtccg gtcccaggag ggggacaggg aggacgacac ggacacggcg
    14521 ccggaaacga cgatagcgct cctcgaacgc ctcgaaggtc tccgcgacag gggggtgctt
    14581 tccgaggagg agttctccga ccagaaggat cggatcctcg gaaagagggg cgggaagaag
    14641 gagtgaaggc ctgtcccggc agcggtgtca ctcattctcc ttcgtcacag ccagcccgga
    14701 tacggggact gcagccggtt atcgcacccg gccggagtag caaagggaga aaacctgttg
    14761 agagattctc acgctgaccc ggccatctcc cgggcaaacg tcttcgcatc tgcgaggtcc
    14821 tgtgcgccgg gatgcccccg gttggtaaag aggaacttcc cgcggcacgt aaagccgccg
    14881 atgaccgttg cacccttcgc aaggagggca tccccatgac cgcgatcatg tgctgtgctc
    14941 cttctgcgcc tcccgacgtg ccggacaggg cggccttccg cccggaaaaa ttccccgacc
    15001 cgatgaactg catgaggggt tcacccggtt ttcccccgta acccccgctg ccggggaaga
    15061 cgaggcgtgc actctccggg aggggtgcat tcgtgtcctg cacgggaacg cccggctccg
    15121 ccgcgatcgc gtccgcaacc ttcctcgtgt tcccggcccg ggaaaagacg atgactgctg
    15181 tatccgtcat acccggggat gaggggacgg tcctgataca tgatgcgatg ggaagggcgg
    15241 aaaaaaatcc aggcacgtga aacattggac taaagagccg gggttggagt cccccggcgg
    15301 gacacgtttt ccaaatcctg caggataatc ggaagacacg gatgacatag accggcaaga
    15361 gaatccaaaa accggtacat gactctgtcg aatgacactg tacaaggaaa ataaaatgac
    15421 aggaattgaa ccggatggct ggtccattca accccttccg gaataccggg gaaaaaaaga
    15481 gttattcaaa gaggattctc aatttcctct cgatgagcgg agagatccgg taaacgccgg
    15541 gttcgtatgt gccacatgtc cagtaatgga ctgcacattc caggtcgtca tctgaaattg
    15601 catactggcc cggtgaaatt acttcggtca aggcaggttg ccctttcctc acacttgtcc
    15661 ggcacagatc gatccgcccg tcatgaacgt ataaaaagta gtaccactgg ccaatcaata
    15721 cccattgctc ttcggctgcc tgtcctgtta tttcgtcaaa aaaaccccag acccggtcct
    15781 gatcacaggg tccgattctc agccaccgca tccttctttc cacgttcgtg tacattttct
    15841 ctcgcctctc ttccccattc cactcttgat cctgctcctg cttccactct gccctgcagg
    15901 aagaggtaca ggagatgaca gattccagtc tcttctcctg gatagaagga aatatccttc
    15961 ctataataat aaatttttct aaaaaccaga atttcataaa aaagctgtgg cgggaatggt
    16021 gcccctttcc gctgaaataa caccatgctt ttggggactc gccggtcgct tcagatcagg
    16081 tttccgtacc gggacgcaca ggcgtccttg taggcaccct cgatgtcgga gtccggaggg
    16141 ctgacctgtc ccggctggaa cgcaagaatc ttcctgatcc tgagcgagac ctcgcggtcc
    16201 cgtgccccgg cgaggagttc ctggccggaa acggcatcag gggaggcgtg caggtccgcg
    16261 tggcagcggg cacagaggac gagcagggat cgctccatct cttcggggga ttgcgggcac
    16321 tcctcccctt ccccggagaa gcagtggatc tcgagctcgt cctctgtccc ggtactcccg
    16381 cagatctcgc agcggcaccc ggccgcccgc ttgatgctgt tggccttggc cgggtgggag
    16441 agcaggaagg gcgatgacga catgaaaagc tcctcgtatt cccgatgagt ggataaccgg
    16501 gtcagaacag ataaattttg gtcccgtggc aggtcattcc gggacgaccc cggggcatcc
    16561 tccttccggg ccgtgtgccc ggattgtcct atggaaggat tgcccccccg ttgtgcatgg
    16621 caggaatatg gtccactctg ggaaaagttc ccccgggaaa aggaaagcgt cctgtcccgc
    16681 ctctcctcat tttgcctgac agggaaaaaa tcctccggca gcacgaaggc ccacggcgtc
    16741 gccgtgcatc caaccgggaa ccgggccctg accccctcac cgcccgtgca gtgtcacctg
    16801 ccgtcttccc cggtggaaag cgcccggatg tacttcctgc cgtctttgag gatctgcttc
    16861 ccggacgggg ttatccggta gatgatgtag ttgccctgct ggtctccttc gatgagaccg
    16921 gcctttttga ggacctggag gtggtacgag agccgcgagt ccgcgattcc cgtggcagcc
    16981 ttgatcacgc agacgcagag cggttgtttt tcgaggagaa agaggatctt caggcgtatg
    17041 gcatcggaac aggccaggta tagtcccttt atggcatcga gcccggaggc agacgggatg
    17101 gcggagacaa gcccctctat cccgccccac cgtgcgaggg acgcagccat atcggcgggg
    17161 atggcggacc ggcccccctc tcctcccccc cttctctccc gtgccttgcg gggcatttca
    17221 aatttagatg aaccttccct ctcaataaag taacctgatc gtcacggggc agggggaggc
    17281 atctgcgtca catcccgggt gaaaggaaat tacccccatg cccatgaagg gaagaggata
    17341 aaaagaagga tgcggcattt cgggggctcc ctgccggcat ggaaaagagg gggggcaggt
    17401 gccccggttc tggcccggag ggggatcaga tgatgatcgc tgccgtcttc ttgtccttct
    17461 cctcgtcgaa gtcggtgatc gcgacttctg tcgagaggat catcccggcg atcgaggctg
    17521 cgttctggag gccgaccctg acgaccttgg ccgggtcgat aacgccccgc tccatcaggt
    17581 tctcgtaggt ccctgtcttc gcgttgtacc cgaacttccg gtcgttgctg ttccggatgc
    17641 gggcgatgac ctctgcgccc tcgacaccgg cattccgggc aatctggcgg agcggttcct
    17701 cgagcgccct ccgcacgata gacacaccga tcttcctgtc gtcgtcgaag tgcagggaat
    17761 cgagcgcaga tatcgcccag aagagcgtga tcccgccgcc ggggacgacg ccttcctcga
    17821 cggccgcctt cgtggcgttc agggcatcgt cgatccgcat cttcttctcc ttgagctcgg
    17881 tctcggtggc cgctcccacc ctgatgaccg ccacgccgcc ggtcaggttc ccaagcctct
    17941 tcttgagctc ctccttccgg aactcggagt cggagatgtt gatctgggac tcgatgagct
    18001 tgatccgctc gtcaagggct ctcttctccc ccttgccgcc gacgatcagg gtcttttcgc
    18061 catcgaccct cacggtatgg gcagagccca gcgactggcg ggagacattc tctatcttca
    18121 tcccgcggtc ctctgagatc accgtcgcac ccgtcaggat ggcgatgtcc tcgaggagcg
    18181 ccttcctctc gtcgccgaac ccgggggcct tgacggcgca gaccttgacg gcaccgcgga
    18241 tgatgttcaa gatcagggca gcgagggcct cgccctccac gtcctcggcg atgatgagga
    18301 gcggttttcc gtcctgcgcc gccatctcga ggatcgggat catctgcttg agggtcgaga
    18361 tgcgccggtc ggtgaccagg atggagggat cctcgtactc ggccgtcatc ttctcgtggt
    18421 cggtcaccat gtagggcgag atgaacccgc ggtcaaactg catccccttg acgacttcga
    18481 ggctcgtctc gaggctcttt gcgtcctcga ccgtgatcag gccgccgtac ccgaccttct
    18541 ccatcgcatc agagatcagc ctgcctatct cctcgtcgtt gtttgcagag atcgtcgcga
    18601 cctggacgat ccgctcgcgg tcgttgacgg gcacgctcac tgatttgatg taatccaccg
    18661 ctgccgacac ggccgcatcg atcccgcgct tgatctcgat ggggttgcct cccgaggtga
    18721 tgttcttcag tccctcggtc aggatggcct ggacgaggag cgttgcagtc gtggtcccgt
    18781 cgccggtctt gtcctgcgtc ttctgggcga cctccttgac gagcttggca ccgatgttct
    18841 cgaacttgtc gtggagggag atctcctttg ctatcgtcac gccgtcgttg gtcacgaccg
    18901 ggttggtcgg cttgtcgatg acgacgtacc gtcccttggg gccaagggtg atcttgacgg
    18961 tatccgcgac cttgttcaca cccgaaagca ggagcttgcg ggcttcctcg ttgaagatga
    19021 gctgcttgga ctgggccatg gatcagtcac cccctgacaa tccgtgccac gatatccttg
    19081 aaggggacaa agacgtacgt ctccctgtct atctcgaagg tctcggcact gtatcccccg
    19141 tagaggatgt ggtccccggg cttgagcggc aggggagtcc cgtcatcgcg ggagccgacg
    19201 gaaacaacgg tcccctgctt cttctgttcc cgggcggtct ccgggatgta aataccactc
    19261 tttgtccttt cttctccctg tatcggcttg acaagaaccc tttcaccgat aggaacgatc
    19321 tccattgtgc ttgtgcacct ccggaaaaca tacaggtatt ggactcaaaa atatttaaaa
    19381 attatcaata ttgtataaat catttcaaca aaaatcaata gatttatatt ttatgtaatc
    19441 agaatcgata ataagtgagg gggcagacgt ggtgcgcggg atcatcctcc ggcaggcaga
    19501 gcgtcccgtc ccgggcggcg gggaggacga ggtgatctgg ttctgccggt gcctcggcat
    19561 cggtgcagga agggacctcg acagggtagc ctcccggatc atcatcgcgc tcctctcgtc
    19621 ccgggcccac gacgagggca tcccggtcga ggagatcgcg cacgaactgg ccgtcactcc
    19681 cgcacgggtc aaccaccaca tccggaggct cgcggaagca ggcatcgtct accggcagaa
    19741 gaagaggatc ttcatccggg gcaggagcct gcgggccctc gtgcaggaga tccgcaagga
    19801 cgccctccgg atcctcgatg acctggaagc cgctgccagc gagatcgaca gggaatacgg
    19861 gatcccgcac cgctgaaccg ggaaaatccc ggccgtccgc caatgggatc caccgggaaa
    19921 agggcatgga aagggatgga acaggctgca ttttcggaca atggttctca ccgggatgaa
    19981 ggtccgcaga aaacgaaaag gagagaatcg ctttcaggat acatgtccat gaccgccggt
    20041 gcggtcgaac ggggaggatt ccaatcacga atgcaacgcg gaaacggagg tgacaggagt
    20101 catggcagag aggtcctacc accgcatcca cgacatcttc aggaggctgc ttgaaaatat
    20161 ccaggatatc atcgtcatcg tcatctgcat gctcctcttc gcactgatga tccggatcat
    20221 ccttggcctc gccgagagcc tggccgggca gctgaacttc cagtacatcg cctcggaact
    20281 gatctacatc ctcgtgctcg tggagatcta ccggctcctc atcatctacc tgcgcgagca
    20341 caggattgcc gtcgacatca tgatcgaggt cggtatcgtc tccatcctcc gcgagatcat
    20401 cctgcacggc gtgctcggga ttaacgccct ctcgatcatg gcactctcgt tcttcctcgt
    20461 tgcactgatg ctcctcctgc ggtacggtgc aatcaggaag gaagaggtcg aaggggttcc
    20521 ccgcgatggt ttcctcaccg agctgaagcg gaccctgaag cgggagaccc gtgactaaac
    20581 cccctttttc tgcccgtggc gggcctgcac cgggtcggtt ctgccgcggc agtctgaatc
    20641 atctgcttca cctgacccgt ccccggcggc tagggaacgg aagaacgggt atcaccccca
    20701 tcgtgcgcgg ggtaccaccg gtgcagggct tcccgccagc gcttcccgtg cacggttttc
    20761 cttcccgctc cccctccacg ggggatacgg gcacccgccg cggtgtcgtg cttcccgctt
    20821 tagcttaatg agggccgggc ctccacacta ctctcatgca catcgaagtc gagggcgttg
    20881 ccggcctccc gatgatccgg aagggagacg accttgcggc cctgattgcc gggcgggtat
    20941 cgttctccga cggggacatc ctctgcatcg catcctcggt ctattccaag gcgaaggggt
    21001 acacgcggtg cctccgggac atcgtcccct cggagagggc tgaaaggatc gcgggaaaaa
    21061 cgggggaaga cccccggttc atccaggcgg tcctcgatgc atcgaccgac gtcctcctcg
    21121 agtacccctt cgtcctctcg gaggtcgcct gcggccatgt cggcgtccgg gccggtgtcg
    21181 accagagcaa tatcgaggac gacatggtca tcctcctgcc acccgacccg atggcggcgg
    21241 cccgggagat cagggaggcg ctgcgggaac tgaccgggaa atcggtcgga gtcatcatca
    21301 ccgatacctg cggcaggtca ttccgccgcg gccagacggg gcacgccatc gggtggagcg
    21361 ggatgacggc gatccgcgac ttccgcggcg ataccgacct cttcggccat gtcctcaaga
    21421 tcaccgagga ggcggtcgtg gacgagattg cggggtttgc caacttcgtg atgggagaga
    21481 gcaacaacgg ggttcccgcc gtggtcttcc gcaactgcgg gacatggcag gggcacgaca
    21541 acctctactt caacgcagac gaggacatca cccgggccct cctgaaggga gcacaccgcg
    21601 gcagcacacc cccgcgtaaa gaaagataat tccccccctt ttcctgcccc ctgcacctct
    21661 cccgctcagg ctgtttttcc ccgtaccagg ccgaaaatcc cgacagcaaa gaagaacgtc
    21721 ccgaaaacga gggcaaagta gtcgatgaaa ccggggttgc caaccagttc catcgcaccg
    21781 aggatgatga ggcccgcccc gcctgcagcc tgcaggccgt tgatgagcac gacagtggag
    21841 accatgggaa cctgtccatt tcctgtttct tccccgatcc ctcacatcac ttgcggtccc
    21901 cgggggagga acggatgaat gccgcaagct tccggaagtc cgactcgagg tcctgccggg
    21961 ccggggggtt gtgggtgatg accgcggggt ggtagacggg gatgatggtc atcccgcgcc
    22021 cggagcggtc atcccgcacc gcgtgtgcgt gtccccggac ctcccggaac gagggaaacg
    22081 ggataccgta caggtcaaag agggtcatcg tcgcagacct tcccatcggg acgagcacgc
    22141 ggggggagag gagcgcaatc tgggctttga ggtacggcat gcaggccgct atctcgtccc
    22201 gcttcggcgc ccggtttccc ggcggcctgc acttcacgat gctcgtgatg aagacttccc
    22261 cgcgcaggag accgcagtcg gcaagcagcc cggtcaggat cgttcctgcc ctgccgacga
    22321 aaggcctgcc cgtctcgtct tcggtctttc cgggggcttc cccgatgaag acgaggggcg
    22381 aagggaccgg tccctccccg ggaacggtcc gcgtccgcga aagggagagg ggacagaggg
    22441 tgcaggcggc aatccgggct gcgagccggt ccatcgacgc ggcgggggaa acgccgggcc
    22501 cgtcatccat gcagaaacat tttccacctg cggtcaaaaa acccattccc atgtgcgttt
    22561 cctccccccg gggatccggg ccggccgcac gggcacgcgg gaaggacgcg gcatcgatcg
    22621 cctgccaaaa acccgcggtg atgcgaaaag ggcgcggggg ctgaccatgg gatggagaaa
    22681 gcacgtctcg cccgggctgc cccctgacct cgcccgccgg ctcccttccg ggtacgaggt
    22741 cataggggac atcgccgtca tttccctccc ggacgaactc cgggactacg cacactccat
    22801 cgcatccgcc atccttgccc ggcacgggaa cgtccgcacc gttctcgacc ggcggcccat
    22861 tccccggggc gatacccggg tcccggaagt ccgggtcatc gcggggacgg ggacgacaac
    22921 gacgtgccgg gagttcgggt actcctatcg cctggacctt gcacgggtct tttactcctc
    22981 ccggctcgcc tccgagcgcc agaggatagc cgggctcgtc cggccgggag aagaggtcct
    23041 cgtccccttt gccggggtag gtccgttcgt ggtcccgatc gcggcccgcg gggcccgcgt
    23101 caccgcgatt gaaaacaacc ccgcgtccgt cgggttcctg cgggagaacc tccggagaaa
    23161 ccgtgtcgcc gcaagggtga ccgtgatcga gggggatttc tacgaggctg cccgctcgct
    23221 cccgccggga ttcgaccgtg ccgtcatccc ggcaccgtac cggagggacg atgcgctccc
    23281 cgtgggggca ggcctcgtga aggaaggcgg aaggatccac atgtacacgt tcgggaggat
    23341 cggggcagaa gatgaactcc cggggaaata cgaggggatg gggtttggca taacccgggt
    23401 ccgccggtgc gggaacgtgg ccccgggcat ctgccgctac gctctcgacc tggtcaggat
    23461 gccgcatccc gcgtaaggga aagacggtgc tgatcacgaa gatctcaagc cttcccctgc
    23521 ccaggcctcc atccatacag ttatcccgcg gtgctgcaca gagactccac catgaaacag
    23581 ccaaacaacc tgcaggttgc agtgttcctc gtcctgttcg cgatcggtgt ctctgcggcc
    23641 tactcgctct acacggcgac aggagaaccc gcatccctcg tcacggggct ggcagccctc
    23701 ctcgtcgcac tttttgcggc cgcagccatc caggttgcaa accagtggga aaaagccgtt
    23761 gtcctccacc tcggccggta caaggggctg tttggccccg gcgtcttcac gatcgtcccc
    23821 ctcgtcgaga cggtcgcgta ctggatcgac acgcgcatca tcacgacctc gtttaccgcg
    23881 gaaaaaaccc tcacgaagga cacggtcccg gtcgacgtcg aggcggtcct cttctggagg
    23941 gtcgtcgatc ccgaacgggc agccctcctc gtcgaggact acagggcggc cgtcagctgg
    24001 gcggcacaga cggctctccg cgaggtgatc gggaggtcgc tccttgccga gatgctcgag
    24061 ggcagggaga aactcgacct cgaactccag aggatcatcg aggagagggc ggaacagtgg
    24121 ggcatccacg tctcgtccgt cgagatccgc gatgtcctca tcccggcaga gctccaggac
    24181 gccatgtcca tgcaggccca ggcggaaagg gaacgccagg cccgcgtcat cctcggagac
    24241 tccgagaggc aggtcgccga gaagttcgag gaggctgccc gcacctacca gaacaacccc
    24301 acggccctcc acctgcgggc catgaacatg ctctacgagg gcttaaagga gaaggcaacc
    24361 ctcgtcatcg tcccctcgac cgtcctcgac acgatgacgc tcggggacac gtccggtgtc
    24421 atcgccctct cgcggacact cggcgggcaa cagcaaccgg cagccgggga gggcatgaaa
    24481 cgggagaagg agaaggagaa agaagctcca aagcctgcgg gagaacccgc aggcggggca
    24541 ctctgaaaag ggcggggtcc tgcccgttcc ctctttttta gcgctcgagc ttcccgatgt
    24601 ggtcggctgc cgcatccgcg agcaggggga tgttcccgag ccgggcgatg tcttccacgg
    24661 cctcgagcac gtggacggaa tcttcgagga aggagaggat atctgcgggg tagacgtcga
    24721 tcccgtactc ctcgaggaga tactggctta tctggcggtg gtcgaggccg ttttcgcgga
    24781 gttcgaggat ctcgcgggaa aacttcctct cgggacaccc gcagagcggt gactccctgc
    24841 agttgcagcg gagaaacgcg tgcacgaacc ggacgatctg gtcgtggagg gtgtgatcca
    24901 gccggtcgaa gttgaggtgg gacgagatgg cttcgagggt cgcaccgtgg aatgcctggt
    24961 cggggatgcg gaaccccgcc agcctctcga gcctccgggc atgccggaag cgggccttcg
    25021 cggctatcac acctctcctg cctcttcgtc gaagttcttg agggacgaga ccgcctctgc
    25081 catgctctcg atctcgatca gccactcgtc aaagagcgtc ggctggtcga gatcgtccct
    25141 gatgtacctg ccgcagcagg atgccccgcc gatcacgttt gccccgacct ctgctgcctt
    25201 atcgagggcc ttttccatgt catccccgat cgctttcctc ccctcgctga cgagagcctt
    25261 gatgtccttc ccgtactctc ccgagaggaa cttccggcat gcggcaaaga ggacgaggag
    25321 cgagagctgg agggattcga cgtagtcttc cagctcgtcc tgcggtgcct cgcccatcac
    25381 gatcgcctcg acctcgttga gcttttcgag tgcttcctcc ttcgtgtacc ggccgttctg
    25441 gtagagtttg atgatcttga ggacagagag ggtcacgtcc attgcaaaat tatagaggac
    25501 ggtgtacccc tcgggcatct catcgctccc cggttccgcc tcgaaacggg actcccggag
    25561 cgtctttatc cagttgtccc accgctcctg gttataaaag atgtagaaca atttgagcgg
    25621 ttcttcctgg cttgctgcct tctccttctt ttttgccatt gtcatacagg taatctcctg
    25681 tatgttaaag gtgtatcgga ttggtgcgag gagacgtccc tgttcgcccg gaaaaagaga
    25741 acaccggggt gatgggggga ttttgggggg tcccggctcc cggccccggt gcatcactgc
    25801 ggtgcaacgg caggctgctt gagcacgagg acagggacgc gggcggcccg ggcgacatgg
    25861 gccgtggttg tcccggggaa acccgggata aaaccccttt ttccggccga cttcatcacg
    25921 atcagcgttg caccttcctt ctcggaaaac gcgacgatct cctcggccgt gctgcccacc
    25981 ctgactgccg tttcaaccgg aacatgccgg gacgagaatg cccccgtgca ctcctcgagc
    26041 tctgcccagg ctgactcggt gagtttccgc acctcgtcct ccgactcacc gtggctgacc
    26101 acgtggagga gggagacgcg gcggggccgc gggagcctcc cgcacgcgag cgccacgacg
    26161 tccggggcag agaagtcggt gcagatgacc acgtgggaga agaggtccgg gcagggtggc
    26221 tttgcacccc ccgccggttc ctttccgggc cggccaacca gcaggaggtc ggtcgttccg
    26281 taccggagga catcgctcgc gacgctcccg aggaggagtg cctcgatgac cccctgtccc
    26341 ctcctcccca tcacggtcag ggagatgccc tctgctgcgg ccacgcggtt gacgacatcc
    26401 gagatgttcc cgcccgtgat ctcctcgacg cgggtcgcga tcgcaaaccc ggggttcccg
    26461 aggctccgca cgtactcctc aaggcggagg cgggcatagt ctgcatcggg attcacgaac
    26521 tccccggcga ccgagggggt tttcgtgtag accacgtgga ggagaaggac atgccgggta
    26581 ccgggaatgg attttacgca ttccacggca tgcttcgaac cgggtgagaa atcaaagggt
    26641 acaaggactt tttcgtacat cgtcggcacc ttccgcggga accgggttaa ggtacaaaca
    26701 ggtcttgcgc cgcagataat aagggatgtg cagggaaggg gaggagtctt gagggtgggc
    26761 acggtgtgca cgctcccctc gtggcgcaag gctggtcccg gttcttcctc cggccgccgg
    26821 ccgggcgtga cgcgtgcctt tcctgccggt tctctttatc catgcgcacg gagaactgag
    26881 aggtaccagg gatacccatg acagtgctgc caccgggacc ggccgtgatg ctccggtacg
    26941 gggaagtctt tctcaagagc gacccggtca ggagggaatt cacaaacacc ctcgtccgga
    27001 actgccggga agcgctccgg tccgaggggc tctctcccgc ggaaaggatc acgaggggcc
    27061 gcatcttctt ctgcggggag ccggccgggc gggtggcagc agtcctgtcc cgcatcttcg
    27121 gtgtcgtcga cgtggcggaa tgcaccctga cccccccgga tccgggtgcc gtcacggagg
    27181 ctgccgttgc acgggcccgg gcgtctgccg gaccggcaaa gacgttcgcg gtccgtgcga
    27241 ggcgcgaggg ggatttcggg atgacgagcc gggaactcgc ggcacgggtg ggatcggcag
    27301 tcctcgcggc atgtcccggc atcaccgtcg accttgataa cccggactac gagctgcacg
    27361 tcgagctccg gcagaccggc ggggtcgtct atgaccgccg gatacccgca ccgggcggac
    27421 tgccgctcgg gacgcagggc agggtccttg ccctcctctc gcccgggata gattccccgg
    27481 tcgccgcatg gctcatgatg aaacgcgggt gcgagatcgt ggcgctccac gtgagccatg
    27541 gagacgggga ggacccctca accctcccgg gaaccctgcg gaaccttgcc atcctctcgg
    27601 gctggtgcag gggatttccc ctccgcctct tcgtcgccga tgcagggccg ttctacgaaa
    27661 agctggcggg gctgcacaat cagcggttca cgtgcgtcct ctgcaagagg ttcatgctcc
    27721 gcctcgggac cctcctcgcc cggcgcgaag ggatcgcggc cctctgcacg ggcgacaacc
    27781 tcgggcaggt cgcatcccag acgctggcaa acatggtcgt catctcgaac gcagcgggca
    27841 tcccggtatt ccggcccctc atcacctttg acaagcagga gatcgtgacc ctcgcacgga
    27901 agatcgggac gttcgacgag agacccggcg acctttcctg tccctttgtc ccgggagtcc
    27961 cggcaacgac ttcccgggag gacgagatcc gcaccctcga agaatctctc gggacggatg
    28021 cgctcctgcc cgggatcctc ggcaatgccc ttgagtatgt cgcctgcaac ggcggggtca
    28081 cccgcaggag cccttaaccg ggcagggtct gcggctgtgc ggacaggttc gcggtgatgt
    28141 ttccggaagg ctgaccggca gcgacctcct gcggggcata ccgcacgccg atgtaggaac
    28201 agtaccccct cgaacaggct atcgcaccgg aagtctggtt aaaaaagagc cgctgccggt
    28261 ttcctgcgtc catcatccac gaatcgatcg cctgggtctc gattcccggg acgtaggatg
    28321 tccactgccc gtagagagtc tcgatcaggg tgtcgttgag ggaaaacccg taactcctct
    28381 tgagggcgag ggccgacgag cctgtccggg gattggtgta gtccaggtac ccgtactgct
    28441 ccatgtccct tgcccgtgcc agggcgaggg cgtatgcccg ttcgtcaaag aggatggggg
    28501 gttttccctc ggcggcgcgt atcctgttga ggtggaggac ggcctgcctg ctctcgtcga
    28561 ctgtcgtgtt cgtcttcagg gcgcccccgg ccagggactg gacccagccc ccggcgaccg
    28621 cgaggatgcc ctgcaccgcg ttgcctgcag cgatcctcgc ccccgggacg agcgcaagga
    28681 tgaggacggc gaccaggaaa gcagcgagga tgaccacgag ggcggtcagg gcccgccggg
    28741 agaggagcgg ccttcgttct tcccttgccg ccgggatgag cgggctttcc ttctcgaagg
    28801 agtactcctc gaggtggaac ccccggacga tggcgtccat gtcctggatc cgcagggtgt
    28861 accccgaatc gacgaaccgc agcttttcga ggaggtcgtc ggccgtcacg acccggaacc
    28921 acttgacctt ccggaagtcg atctggcccg ccggataggt gctccccctg cagaagtaca
    28981 gccatgacgc tgtcctccgc aggttctgct ccccgacgtg cgggaaatgc tcgcggcaga
    29041 ccgggatcat cctgtcgatg aagtcctgcc tgtggatctt tgcctggagg aagaggttgg
    29101 ggagggggat cgggccgtcc tttgtcccga cttcccagtt gccgttttcg aggccccgta
    29161 tctcaccgcg gaatgctttg aggtcgagga ggaccgggcc gttccgcgtc aggatgatgc
    29221 agtcgatctg gccgttggca acgagcacgc cggtgaggat gtagacgggc tcctgtgcgt
    29281 actcctcccg gaggatccgg acgatctccc ggagctgccg gaactcgtgc tcgagcttga
    29341 tcttctctcc cctgaaaaac cggattccca ttgcccgtcc cctgcactat ccgtgcagat
    29401 ttactggaat ggtatgctct tttattctga tataacttgt caaaacgact gccggggaat
    29461 ccaccggctt ttttgctccc gcgtgcaata cagggtgaag aggggtcttt gggggatggc
    29521 ggaaagaagg cgtgcacgct tcgggggatg ggagagggtg accatccgcg acgacgcggg
    29581 ccggatgagg gaggccattg cacccgtcat cgtctcggcg agccgttcca ccgacatccc
    29641 ggcgttctac ggcgactggt ttatccgccg gctggaagcc gggcatgcgg cgtgggtcaa
    29701 cccgtggaac ggtcgttcca cgtacgtctc gtttgcaaaa acgagggcaa tcgtcttctg
    29761 gtccaagaac ccgcgacccc tcctccggca cctcccgcgg ctcgatgccc tggggtactc
    29821 gtactcgttc ctctacaccc tcaacgatta ccggcaggag aacctcgagc caaacctccc
    29881 tccgcttgcg gagcgggaga ggacattcat cgatctctcc tcccggctcg gcccccggag
    29941 ggtctcgtgg aggtacgatc ccctcctcct ctcggacgcg ctctctgtcg atgacctgct
    30001 ctcgcggata gagtccatcg ggtcgcgcct gcacaggtat acccggcggc tcatcatcag
    30061 tttcgtggac atcgcgaggt accccaaggt ccggtcccgt cttgctgccg gcggtcatcc
    30121 cggcgtccgg gagttctcgg agaccgagat cgatgcgttc tgctcggggc tttccgatat
    30181 tgcagccggg tgggacctcg aggtctctgc ctgcggggag aggcgggatc tctcacaata
    30241 cgggatccgc cccgggcagt gcatcagcgc cgcccggatg cgggaagcct ttcccgggga
    30301 cgaaacgctc ctttcgttcc ttgcgcctcc cccgggcaca agcggagtca cgggggaggc
    30361 tttcctcagg gacccgggcc agcggaagga atgcggctgc attgcgagca aggacatcgg
    30421 ccggtacgcg acctgcatgc acctgtgcgc gtactgctac gcgaatgcca cggaggcgac
    30481 cgtggtgaag aactggacgc ggcaccggag gatgatggag tccggcatcg ttccggaatc
    30541 cattgccggg accggggaag agatataacc cggcggggca acagcagagt atgccacgac
    30601 gcgatcccct cacgccggaa cagaaatggc tggcagtcac ccggttcgca accgccctcc
    30661 cggtcctcta cgatgtcacg ttcagggaga ggatcggcga cgagtacgac aggctcgacc
    30721 agcagatctg ggtccgtctc gcaacagtag cgcgtgattt tgccaccagt tcgggtcttc
    30781 cggccggaaa cgccggggag ctcatggaga cgctcggggc actcctcctc gcgctgttcg
    30841 ggccggaatt ccggatggaa aatgttcccc tcgacgaggg gagggccgtt ctcatgatta
    30901 agcggtgccc gtttgcgttc cgcgaggccg aggtccgggg aggaccggaa aacctcctcc
    30961 cgcggtgcct cgccttctcg atcgcaacgg tcgaggcgct caacccggcg tttaccctcc
    31021 gtttcgtgcg gagcatgtgc atgggagacc gcacctgcga gctcaaggtc atgaggcgcg
    31081 aggacgccga gcgggacgat gcacggtagc ggggcaccgg cagcacgggg acacccgcga
    31141 ataaccgctg ttatcccgcg gttcttttca ggcagtcctc tttgacctga cgagggaaaa
    31201 agcaatcccg aggcagcaga ggcagaaaaa gacgaagaat gcggtgtcga ggctcccgat
    31261 gaagagggat ggttctgcat ccttgagttc ctgcctcccg atgaagaggg caaagatggt
    31321 cagtgcaatg cccatcgaga acatctgccc gagcaggcgc atcgtcccca ccatccccga
    31381 ggcaacgccg tataacctct tttccacgga gccgaagatg gcgttggtgt tgggggatga
    31441 gaagatgcca aatcccgtcc cgaggatgac gaggcaggcg atgatgtggg ggatcggggt
    31501 atccctgccc aggaatccga ggaagaagag gccggtgacc acgaagacca tgccgagcgt
    31561 tgcaaccctg cccgggtcca cccggtcaga cagccttccc gcgaggggcg agaagagcgc
    31621 ctgggtgacc ggctgcgcga cgaggatgag cccggcataa tctgcaggca ggtcccgtgc
    31681 aacctggagg tagagggaga ggaggaacgt gaccgcatag gtcgcgctgt agttgatgag
    31741 ggcggcaagg ttcgagaatg caaagaccct gtttgcgagg aagagctgca tggagaggac
    31801 ggggaagggg acccggagtt cgaatgcggc aaacgcgagc aggaacgcga cacccagcag
    31861 gacgaggatt atgccggctg ttccggggag gagggagagg ccgtagatga gggagacgag
    31921 cgatgccccc cagaggaggg agccggcata atcgaacctc tccccggcag cctcccgcca
    31981 ctccgccggg accttccgga gcgtcaaaaa gacgcaggca atcccgagcg ggacgttgac
    32041 gaggaatatg ctcctccacc cgagcgtctc ggtcatgatc cccccgagga acggcccgag
    32101 cgagaggccg acgtagactg ccgcaatggt gatgccgagc gccttacccc gctcgcccgg
    32161 cgggtacacg gaggagagga tggcaaggct cgtcccgaag atcatggcgc acccggcacc
    32221 ctgcaggagg cggaacgcta tcagccagaa tgcgccggtc gaaaaggaca cgaggaggga
    32281 cgcgcaggaa aagagggtaa tcccggcgag aaagacgcgt tttctccccc ggatgtctgc
    32341 cagttttccg aacggcacga ggaaaacgga aatggtgagg aggtaggagg tggttatcca
    32401 cgagagcgtg acggcatcga gcgagaactc ctccccgatt gccgggaggg cgatgttgac
    32461 cgcagagccg tcaaatgggg tgatgaaact gctgacgatc gcgatgaaca ggatgacccg
    32521 cctgatcccg ggacccgcta atctggcgtc ttttaatccg tggcacaccg aatatcccgc
    32581 ctctttctcc cgatcctacc cgttggggcg gaaaggtaaa gagaattgcc ggccggtgcc
    32641 ccgcggcgcc ggatgactat ttctccttgc cgcaccctct ctgtacaggt ccggagggca
    32701 ggtgaataag ggcagatgaa agttggcgtg ctctgttccg ggggaaaaga ctcgctcttt
    32761 gcgtgcatgt gcgcgatgca ggaggaggag gtcgcctgcc tcatcactgt ctttcccgac
    32821 aacccggaga gctacatgtt ccacaccccg aacctgcacg tggtccggct ccaggcccgg
    32881 gcggcgggca ttcccctcgt cgcggggacc agccggggga gggaggagga agagctggct
    32941 gacctttccc ggacagtcgc ggaagcggtg gaaaggcacg gcatcgaggg cgtggtgacg
    33001 ggagccctcc agtcggtcta ccaggcatcg cgggtccagg ccatctgcag ggacctcgac
    33061 ctctggtgtt tcaacccgct ctggtacgct gaccccggcg agtacatgga gacactcgtt
    33121 tcgtccggtt tcgatgtcat cgtctcggcc gtcgcatccg agcccttcga caggacgtgg
    33181 ctcgggcgcc ggctcgaccg tgcagcgctg caggatctcc gcaggtacgc ggagaggtac
    33241 ggcacgtctc tcccgggcga agggggcgaa tacgagaccc tggtcctgga cgcccccttc
    33301 ttccggcaca ggatcgtaat cggggaggcg gaggcggtct ggcagaactt ccgcggcgtt
    33361 ttccacgtga aggaagcatg gctggagggg gatgcatgat actcctcgcg gggctcggat
    33421 tccgcgacgc ggcactcctc cggagcgagt tcgtgcggcc tgtcgcccgg gttgccgggc
    33481 attggggtgc agaatggagt tactgccact attcccgcct cccggacgac ccggccgacg
    33541 ggtacgatgc ggtcatcctg tgcgggactg ccctgaagga taccgggtac ctgcgggaga
    33601 tcgggcggtt ctcctggctc atcgaagccc cggtccccgt gctcgggatc tgtgcgggca
    33661 tgcaggttct ctccctcgtg cacggcggga cgctccggcc ggcctgcgag atcgggatgg
    33721 tggacgtcag ggtgctctgc ccaaaccccg tcctccctcc tctcccctcg ttccaggcct
    33781 acgcgctgca caggtattcc tgcgaccctc cgccgggctg gacgacgctc gcggtctcgg
    33841 aaacctgcgt ccaggcagtc tcccacccgc acctgcccct ctttggtgtc ctcttccacc
    33901 ccgaggtgag aaacggggtc gttatcgaaa ggttcctctc cctcgtgtat cacgggaaag
    33961 agggagaggg ggaggagggg caggatgccc ctccttcagg acacgggtag cccgttctcc
    34021 cgggcgatcg cgatgaagga ctctgccacg tactctgcct gggcccggga aagaccgtag
    34081 cagttgaact tccacacccg ggtcgcgccc gggatgatac cggtgatccc ccggtccttc
    34141 agggcgctcg tgaagaagaa ccccttcttt ttgtgctttt cggccacgcg gtcgaaggac
    34201 tgcgaggtgt ccacgcgggt cagggtgtgc ctgcgcgggt actggctcag gatggccgtt
    34261 cccccgatcc gcttcagtgc atcgacgacg agggcggtgt ttgcgagttc gctgtcccag
    34321 cggaggacac gctctctcac ttcgggaaac gaggccatca tcccgacgag ggtcgctccc
    34381 atcagggtgc agcccatcat ctccacctcc ttgatgccga acgtccggga cgtgacgtcc
    34441 gtgcgggcag ccgtcgtcct gaagacctcg cctgcccgct cgttcctcac tgcgagcacg
    34501 cccgagggtg cgggtgccgc catgctcttg tggccggaac ccacgacaaa gtccacgccg
    34561 aggtcttttc cgtccacggg catgatgccg accgtgtatg caccgttgag aaggacaggg
    34621 atgtcgtagc cgtgggctgt cttcgcgatc tccctgaccg ggtggaggtt gccgtagctg
    34681 tagtccacgt ggtcgaggaa gaggagcggc ggtgtcctgc cggtctttgc aatgacctcc
    34741 tcgatctttg cggcggcggc atcgggtgtg atgatgttat cgggggatgc cgggatctcc
    34801 atgggaatgc cgccacgtgc ctcgattgcg aggatctcgg tgtagtggga gagggcggtg
    34861 accaggaccg gatctccctt ctccacgtac gtgtctgcga ccgcctggaa cccccggcgg
    34921 gcaccgggaa cgacccgtgc gacgtccatg ccgacgaact ccgcgagttc ccggtggaac
    34981 cggtcgatgg gaggcttttt gatgtagtcc agccggttgg gcttcctgca gttgtcgcac
    35041 acggagtacc cgtcgccgta cgcgatcagg gccttcatcg ccgcggcggt gaggcggccc
    35101 cctgcctgga tggggtcgat gttgatgctc tcctcctcga cggcgcggac ctcgatatcg
    35161 ccggcacact tcatggcaaa agctcccgtt tcagcacgcc gacctgcttc tcgagccccg
    35221 cgatgaggga ctcgacctct tccctttcgc ccggtcccag cctgtggtgc ggtgcagtct
    35281 tgcggaggat gacgcggatg tcggaaagga tgaacatcgc ttcaaaaagg gctacaatcg
    35341 cggctttgga caccaaatca ccatactaat atgcggggca ggactataag ataccggatg
    35401 gacagggcat gcacattcac cctgcacggt cgtcccttta tgggaaacag gaacggacac
    35461 ggtgatgatc gatgaagctc gttcacatcg ccgatacgca cctcggcctt gcccagttcc
    35521 agaaggtgga cccggatacg gggatgaacc tccgggaaaa gctgatttac acgaacttcc
    35581 ttgctgccat cgaccggatc atatccctcc ggccggacgt cgtggtgcat gccggtgacc
    35641 tctttgacca ggtcaggccc aagacgatgg catacacgac tgccctcgag gcactggaga
    35701 ggctctcgga ggcaggaatt cccctcgtcc tcatctcggg caaccacagc atgcccaaga
    35761 cgcggtacac gccgtccccc ttcagggtcc tcgagttcca ccccggcacg ctgcacgcgg
    35821 catattccta ccggtacgag cgcgtggaga tcggggaggc ggtcttccac ctggtcccga
    35881 acatgctccg ccccgagcac tacagggaag cctacgacag gataacaccc gaccaaaaca
    35941 ggttcaacgt cctcgtcacg cacggtcttg cctccgccct gaaagagaag cggctgaaca
    36001 cggtcgccga acacgagatc gatgcaacga tggtctcggg cgggggcatg ttcgactaca
    36061 ttgccctcgg gcacttccac ggccaggtac aggtcgggga acgggcatgg tactcgggct
    36121 cgtccgagta catcacgtac ggtgagatcg gggacatcaa gggcgggctc tgcgtcgatt
    36181 tgggcagggg catcgtggat cacgtccccc tcccgcacac gcccatggcg gatctcggca
    36241 ccatcgatgc ccgggaagtg ccgccccgcg acgtgccggg gctcatccgg cagaggctcg
    36301 aagtgaaccg ggtcggcccc ctctccatgg caggcgtcac cctctgcttt tccgaccggg
    36361 aacaccagag gcagcttgac gagaaggagc ttgccggtgt ccgccgcgaa ctgctcgacc
    36421 tcaagatccg gataagcgtc ccgggcgagt acaggaaagg cggggagacc cgggacatcc
    36481 gctccatcga ttaccttggg gagttctcgc ggttcgtggc cggaaagaac ctcgcacagg
    36541 gtgaacggga ctttattgcc gagtacggat cccgggcgat atcactggca ctcgaggagg
    36601 aggggcccgg tgctgattga gaggctcgtc ctgcgcaact tcaagcggtt cggggacgcg
    36661 gagatccgct tccgggacgg gatcaccggt atcgtcggga acaacggcac ggggaagagc
    36721 agcatcgtgg aggcaatcct gtttgcgctc ttcggggtgc aggggaccgg cgtccagtcc
    36781 gactacatcg tctcgtcctt tgccggggag aaggcaaaat gcgaggtgag gctcgacttc
    36841 caggtccagg gagtgcggta cacgatcacg cgggcattcc ggaagggggg acagaccgtc
    36901 cacgaggcac gcctgcacat gggcgaaagg ctgcttgcct ccggcgtctc cgaggtcgcg
    36961 gcagaggtcg aacgactctg cgggatgggg ccgtccgact tcaggaacac cgtctatgct
    37021 gcccagaagg atctccccgc cctcctcgag agccgccccg gcgcccggaa ggaatggttc
    37081 atgcaggcac tcggcatcga gaaactcaag gcccggagcg acgaggcggt cagggaatgg
    37141 atcgacgagg cggaacgggc cgtcgagcgc gagaaaaaca ggctcgcggt gctctccggg
    37201 cagggagacg tctcggagat ccctgtcctt gcggaggaac tgggccggat cgggcaggaa
    37261 attgccggaa aggaggcaga aaggcagcgg ctggaagagg tatccgcaat ccttgcaagg
    37321 gccgcatccc tcgtccagtc ggatgccgcc ctcgaagcga ggcagaaaca ggcggaatca
    37381 gatctcctcc ggcttgcaac ggccgcagac cggctcgcgg aactcgcacc cgccgtgagg
    37441 aggtttggcg agctcgagga agaactcacc cggcaaaagg agaaggaaca gcggttcgcg
    37501 gaactccggg accggatggg aagggcagag gcagcggtca gggccgggaa aaagaggctt
    37561 cttgaccttt ccgagcagat cgatgtctat tcagccgagg ccccggaact cgagggtctg
    37621 aaggacgttc ccgaccgcct cgcggaggcc cggaaaaccg ttgccaacct cgacaaggcc
    37681 tcgttcatct ggcagtcgct ctccgactta tcttccctcg cggagcggat agcccgggac
    37741 cttgccgggt gcgaggagga cgagcgggcc ctcctcgccg aactggcgga actggagggt
    37801 ctccgtgaaa agagacgtga actcgaggag ctggcaaaat cgcggagcag ggcatctgcg
    37861 gaatgtgccc tccgggctga agccctcgca caggagaggg cagccctttc ggcggactgg
    37921 gaacgcatcc ggtcgtcggg ccgggagggc acctgccccc tgtgccacca gaccctcggt
    37981 gagttcttcc cccgcatcga gcaggagtac agcgggcggt tctcccgcat cgacgaggaa
    38041 cttgattccc tttcccgcac gctcgaagcc tgccgcgggg aggaggaacg gatcgggaaa
    38101 gagcttgcgg cagtcgaccg ggccctcgaa caactctccc gcgtcgggca ggccctccag
    38161 gagacgaggg cgaagaaaaa ggggctgtct gacaggctcg aagagatcgg gagggacagg
    38221 gaggcacgat acggggaact ctcgctcctc ggcatcaccg cgtacagccc ggaagcccac
    38281 gcacaggcac gggaatccgt caggctcctc gaagtgcagg tgcagcgcct ccaggaactc
    38341 cggttccacc aggaacgcct tgctgcactg acgcgggaga gggaccggct cctcgacgag
    38401 atggagaggg agatggcgga cctccggtcc ctcggggcag agatcgcggc actggactac
    38461 gaccctgccc tcctgaaggc aggggaggag gaatacaggt cgctgcgccc ggcacgggac
    38521 gaggcgatcg cgctccggga acggctcgcc cgtgaaccgg agatccggcg cgaaatggac
    38581 aggataaggg aagagaggga gcagatccgg gaactcctgt cctcctgccg cgagaacctg
    38641 gcccggctgg ggttcccgga ggcagactcc gcttctgtca gtgcacggct ccaggagctt
    38701 gcgcaggaga tctcccggct gaacacgagg caggggagcc tccaggagca gcatgcccgc
    38761 ctcctctcca tcgctgcgga gatggaaaag gcacaaaagg aacttgctgc cctcgaaaaa
    38821 aggctcgtcc tcctccgcat cacgagaaag accgttgcgg agttcgtcct gtacctggcc
    38881 ggtgtcatca gggccgatat cgaggacgag gtgagccgga tcctctcggg gataacctcg
    38941 ggcaggtacg accgggtcat cgtggacgag gacttctccg tccttgtaca ggacatcgac
    39001 ggtgactttc ccgtccagcg gtactcgggc ggcgagcagg acgatatcgc ggttgccctg
    39061 cggattgccc tctcccgctg cctctccggg ctgcacggcg tttcggagaa catgttcctc
    39121 gtctttgacg agatattcgg cagccaggac gaggaacgga gggcaaacct cctccaggcc
    39181 ctccgctccc aggaggccca cttcccccag atcatcctga tatcccacat tcccgagatc
    39241 cagggagagt ttgcgcacac tctcctcgtc gagatggccg acgaccagaa gagcaggatc
    39301 gtggaggtat catgaatgca gggtgatgcg taccgggagt ccatcaggcg ggttgcccac
    39361 gcggtgcggg actgcctgcc ccgggacatc gggcgactct ttgcggaaca cagcggaatg
    39421 acccgcggtg acttcttccc gctcacgccc cgcagggacg gcatcatccg tgccgtcgac
    39481 ggcagcaacg caacggtcat ggaggccgga aacatggccg tcgtcgcagc gagggccggt
    39541 ttttcatcct tctccggcga aaaaaggctc cccggcggcc tcacccccgt ccttctcctc
    39601 caggcagggc cgcgggacgc cgaacgcgag ttttcccacc agtacgggga gtgcttcggt
    39661 ttcccgccga gaagccccct ccgcgtggac gatacgtcgc gggctgccgc ggcgatgcgg
    39721 gacacgctcg agtactgggt tgcctcggtc tgtgcagggc accaggagcg gggcgggctc
    39781 ctcctgctcg acggcgcact ccgggtctcg gaggagagcc acgaccccgt cctcgttggg
    39841 atcatccggg aatgccagtc acggggagtc ggccttgctg ccgtgtcgaa acggaccgcc
    39901 gcgacgtggg gggagaggta tcccctcctg cctgccgtga gggctctttc ccgtgacctg
    39961 ggcgtgtcat cgccctggtg ggtccggatc gacgaggaga tcctcgaccg gacgcggtac
    40021 tcccagtggg aacacggcga tatattcgtc tgctcgctcg cacgcgggaa cgcactgccc
    40081 ctgaaagccg agctgccgag gggctgcgac gacgtgacgg cccatgccat cttctccctc
    40141 ctctcgggct gctccgacga cgcccgggcc gagggatacc cctatcccct gctggatgcc
    40201 caccggaacg tcgtgataac ggcagacctg ctcgaacaga tcaggtccga cctgctctcc
    40261 gggttcgcgg aggaggggct gcttgcccgc gacatcggcg agctctttgg tgattaccat
    40321 gatacgttta gacgatactg agacgcagga ccgctcgaag tggcgcctga tcgggacgag
    40381 cgtgctctcc taccggttca tcgtgcccca cgacgagacc gtctttgtcg gagacatcat
    40441 caagatcgag gacgtcagca agggccttgt cttctttgca cgggtaaccg acctcatcca
    40501 cgagagcaac ttcgcagacg agaaatggga cacccgtccc tacacgggcc ggttctacac
    40561 tctgggcgag gacgtgttcc tcggggtgga ggccgtgccg ctcgggtacg tggacacggc
    40621 agggaagttc cggaaacccc ggacaatccc gaccaagttc tcgcccgtgg gcgtcccgac
    40681 ggaggacgac ctctcgttcc tctccacggt gatgggtgac atcgaggtgg gcgtgatgag
    40741 gacggggcag gacgtgctcc ggggcgtccc ggtccggatc cacagcagcg tgctccccca
    40801 gcacatgggc gtctttgcaa cgacgggcat gggaaagagc aacttcatga aagtcttctg
    40861 cgcctcctgc atgcaggcaa ggcagttcgg gctgctcatc gtggaccccc acggcgaata
    40921 cctggcaggc gggcggagct ccacgggcga gccgacgaag gggctcatcc acgtcccggg
    40981 gctgcgggac ggtctttcgg tgtttaccac gcggtcagag gagcagcgga ggcagtacag
    41041 cgcaagcagc ctctccctcg agtacgacga catccggatg ggggacctct ccgccctgta
    41101 cgacctctcc gacccgcaga gggacatcct cgaggcactc ggtgactaca gggggagcac
    41161 ggtcatcggg ttcttctcgc gcctcgaccc ggaagagttc acacccgcca cgtaccagtc
    41221 cctccagggg cccgaccggg atatcgcctt ccgcctccgg acgtcgaatc ccgggccgct
    41281 ccgcgtcatc aagaggcgtc ttgagaacct ggtcaagggg aacaggaagt tcttccggga
    41341 gaagggatcg tgcatcccgg atatcctcgc agccctcatg gaacggaaag tcgtgctcgt
    41401 ggacatcccg gggatgagcg aacggagcga actcttcgtc ctctcggtgc tgacgcgtgt
    41461 tatcctcgag caccagaagg aacaggccga gaggtacgac agcagcgagg ggacatcacc
    41521 cgcgctccag cccatcctga tcacgatcga ggaggcccag cgcgtgctcg gggcaggggg
    41581 ccagtcaacg caggtcttcc gcgagtgcgc catggagggg cggaagtttg gagccgggct
    41641 ctgcgtcatc acccagcagc caaaaaacat cgacccgaaa gtccttgccc agatcaacac
    41701 gttcgtcatc atgggccttg gcgaccgcgg ggatcgggag accatcgcgg gctctgcaaa
    41761 acaggacctc tcccggatgg ataccgagat ccagacactc gagcggggcg aggcgatcat
    41821 cagctcgttc tcgataccct tcccggtaag cacgaggatc cacaggttcg aggattacat
    41881 cacgcagatc ccggcgaaaa ggaggacgcc cctttccgag gggctcgaca cgactttctg
    41941 agcggtcccg ggtcaggacc cgctgtcctt cttttccctg cgggccgaca ccgtcttttc
    42001 gacaggggat atggagacag cgttgacgac aggatccccc gtgaccacgt acctcttcat
    42061 gacctgcccg aatacctcga caacgtcccc cttcttcacc ctgtaccgcg gggtggtgaa
    42121 catcttgacg gatatctccc cgctccggtc ggcaacgagg tactgggggc ggttgatgaa
    42181 ctggaagtag accctctcga cgaccccctc gatccggacg atctcgccca gcatgtgggg
    42241 gttgatcatc ttgatccgga cgggccgggc cttgtcccgg tacatgggct cgaggtttgc
    42301 atactcgctc tggctcatgt agttgagggc gagggggatg acgagcagga ggatgaccgt
    42361 cgggataccc cagacaaggt acacctggtc ccctgtgaca aggtacgtgt aaattaaaag
    42421 gatggagaag atcccgacca ccacgagggc gaggatcgag accttcgcgt ttacctctcc
    42481 gatcttcatt cagttccgtt acttgagggc tgcgatctct ttcctgaatg caacccagta
    42541 aatgacacca acgaagaaca tgccacccac gatgtttccg atcgtgacga tgatcatgtt
    42601 gttcgtccag aaggtgaccc agttcagacc tgcgttgatc ttggcggggt cagtgatgaa
    42661 gccctgggtg aggatacctg cggatatgaa gtactggttg gcaatcgagt gttcgaaccc
    42721 ggtggaaacg aagcacatga tcgggaacca gatcccaaag aacttaccca cagcatcatc
    42781 ggcacagata ccgaggagga tggccaggtt gacgagccag ttacaaccga tggctttgag
    42841 gaacgctgac cacatgccca tcgtgccgac ataactcact ttcgcggacg ctatggcaat
    42901 ggccctggaa ccaaaggcgg tcaccgtcgc tgctcctgct gcatcgaacg tcacgaacgg
    42961 accatttgcc atgatgtagg catagacaat agacccgatc aggttgccga tgtagaccca
    43021 gacccagagg ttgatgacct gcgcccagga gaccttgtgg atgaatgcag ccatgggggc
    43081 gagcattgcg tcaccggtga agagttctgc accggtaagc acggtgatga taagcccgac
    43141 agggaacaca gctcccgtga tgagctgagc aaaccctgcg ctcgccgttc catagcggag
    43201 tgcggcgtca gttgcaagta tccctgtact gcacactgtt gcaagaccgc cacccattgc
    43261 gatgtaggct ccggacatga atccacgcat gatcatgttc caggctggca gtcctacctt
    43321 gtacttcccg gcatcgcctg ctttcgcgac gattgctaca gggggatgaa acaccatttg
    43381 ttacacacct ctcgaatgtc tacctatact atacccactg attcactttg cgtataggtt
    43441 caaaactaaa atcctttctg gttttattaa aatctttcta aatgattttt gcactgcatt
    43501 ggcgttttgc aataatttaa accagattaa tgagagagag gcactttttc gtcattcaaa
    43561 aactttctcc tgcgggtatc agacgggacg gcggcgccct gcagcgtccc gggagtacct
    43621 cccgaactcg ccccctgcga ggatatcccc ggaaaagaca gggccgtccc tgcacacccg
    43681 gagtcccccg ggatcgatgc agcaggaacc gcagacgccg acaccgcact tcatgtaccg
    43741 gtgcaggctg aaatnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    43801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncagcag
    43861 gaaccgcaga cgccgacacc gcacttcatg taccggtgca ggctgaaata acccttctcc
    43921 gggcagcccc gtccggaaag gatgccgaga accgcggcca tcatcctctc gggcccgcag
    43981 acgaggatgg cgtcgtacga tgagacgtcc tcgttgccga gcaggtcggg gacaaagcca
    44041 tggaacccga gtgtcccgtc atcggttgca accgacaggt ccgcaaggga ctcaaacctt
    44101 tccctgaaga ggagttcccc ggcggaccgg gcgccgagga ggaccttgtc gacgccaccg
    44161 gccacgaccg ccgggaggat gggggccgca ccgacacccc ctgcaaccgc aagcatcctc
    44221 cttttttgcg ggaagccgtt tccaaacggc cccctgatac cgatgctgtc acccggtccc
    44281 agccggaaaa gggcggcggt cgcatcgccg acacgctgga ccgtgatcga cgatggcgag
    44341 gagagtgcca tcgggacctc gtcgactccc ggcacccaga ccatcacgaa ctgcccgggg
    44401 acaaaggaaa acaccctgtc gaatgcaaac gttgcaaccg acggggtctc ccgcacgaca
    44461 cgggtgatcc ggaccggaac gggcagcccg tcactcatgg gcgcacccca cgatctcttc
    44521 cgggggaatg ccgtccgggg cgtacagttc gctcccgata cgggagaaga ttgagatatc
    44581 ctccatcacc gcggacccta tctcgactgc aactgcaccc gccatcatca tctccaggac
    44641 atcggcagct gacgagacac ccccgcaccc gatgatgggg agggaacagg cctcgtacaa
    44701 ctcgtagacg caccggactg ccaccgggaa gatggccttt cccgacaggc cgccgtaccg
    44761 gttgccgagg acgggccggc ggagcccgac cgagatccgc atcgccttga gggtattgat
    44821 ggcaacgatt gccgatgccc cgccccgttc cgcggccatg ccgatctcgc ggatatcggt
    44881 gacgttgggg gtcagcttca cccacgtcgg cagtcccgcg gatgcaacag ccctcgtgca
    44941 ctcctcgacg aggacagggt cggtcccgag cgccgccccg taccccctcg cgtggggaca
    45001 cgagaggttc agttccacgc ctgcaacctt tccccggaac caccgggaga cggtcgcgca
    45061 ctcctccggg gaccccccga agatgctggc gatcacgggc cggcctgcaa ggggtgcgag
    45121 ttcgtccaaa aactccatcg agggattggg gagacccatg gcgttgagga gcccgcagtc
    45181 gagggagacg aggcagggac cgggatgccc cccgaggggg accgggccga tggacttggt
    45241 cacgactccc ccggcaccgc tgccgaggat gcgcgagagg gacgctccgg tcgttccgag
    45301 gatcccggca gcgagcacga ggtggttttt cagggtgacc ccgccggcgg aaaccggacc
    45361 gggacggagc gtgagcatgc gtaagagagg tcgccgcgat tgtaattatt tattcttctc
    45421 tcacgcgaat gatagtgggt atggcacgga tctcggtcct cgggacaggc aggataggcg
    45481 gtgaggtcgc atacctctgt gcggtgctcg ggcttgcaga cgaactggtc atgtacgatg
    45541 ctgtggccgg cttcctccgg gcccaggtcc tcgacctcct gcacacgggg ctcgacgtgc
    45601 cggtcagcac cagctggaag gacgctgccg ggaccgacat ctgcatcttt tcggccggga
    45661 taccccggac acccgctgtc aggacccgtg cggacctcat gcatgccaac ctgcccgttg
    45721 catccgagtg cagccaggcc atccggaggt tttcgggaat cctcatcacc gtgacgaacc
    45781 cgatggacgt aaacaattat tacctctgca ggaaaaacgg gcttgaaccg gggaggtgta
    45841 taggtttcgg gggccaggtg gactctgcac ggttcggcct cctgctccgg gagagaggca
    45901 tttcgggccg gccgtttgtc atcggcgacc acggcgagaa cctggtcccc ctcttcagcc
    45961 acctcgacga taccgtggac attcccgtgc gcgaagagat cctcggccgc ctccggggat
    46021 cgagcatgga gatcatccag ggcaagggag ggaccgtctt tggtcctgca taccatatag
    46081 caatgctgat caggacgatc ttaaaggacg aaaggaaagt cctcccctgt tcctgcatcc
    46141 ccgacggcga atacggcgtc cgggggtgtt ccatcgggct cccggccgtc atcgggcggg
    46201 agggaataca cagaatcgag gagtggccgc tggacccgtg ggaacaggag aaatttgcgg
    46261 ctgcgcagga tgccgtcacg ggcctgtgca gggaactcgg agtctgacac atctcatgga
    46321 attatccggg aaaacggcag gagtggaaaa aggaggcaac gggagaccgg gggaggaggg
    46381 gggcctcctt gtctccgtga tgcagatcga gtataccgtc ggtccctccg gccccgtcat
    46441 ccacgtcttt gggcgggatc gcacgaaaga ggctgtccac gtccaggtca cggggttccg
    46501 cccctacttc tacgtcccgg cagagctcgc tgccgcggcc ccgccgtcgc cccgggcgga
    46561 agtggaggcg ggaaagaagt acacctcgat caggggagag gaactggtca ggatctacac
    46621 gcaaaagccc accgatgtcc gcgaggagag ggagaggtac agggcccact tcgaggccga
    46681 catcccgttc acgacgcggt ttgcaatcga ctgcgggata cgcggggggc tcttttcccc
    46741 gtcacccata gcggattaca gggaggtttc tcccgccgac gcggacgttc ctccccggat
    46801 ctgcatggtg gatatcgagt gcgaggacgt gcgcgggttc ccgcagcctg cacgggacgc
    46861 catcgtctgc atcacggcct gggactccta cgaggacaag tacagcacgt tcctcttcgc
    46921 tcctcccggg acacctccgg acaccgggtg gctcgcgaag gtctctcccc ggccgtcggg
    46981 gtgctttgac cctgcccggc acgaggttgc cgtattcccg gacgagaagg ggatgctgca
    47041 ggcatttgcc gcctacatcc ggaaaacgga ccccgatatc ctctcgggct ggaacttcgc
    47101 ggagttcgac cttccgtacc tctcccggag gatggaggtg ctttccctgc cgttttcagc
    47161 cctctcgcgc ctcgaagggc agaccgaacg gctcgctgtc cggggcaggg cccagttcga
    47221 cctgctcctt gcctaccgca agatgcatgc cacccagaag gaatcctacc ggctcgatgc
    47281 ggttgccgag gcggaactgg gtgacacgaa ggtccgctac agggggacgc tctcggacct
    47341 ctggacgagc gaccccgctc tcctcgtgga gtacaacttc aaggacgtcg cactctgcgt
    47401 gggtatcaac ggcaagaaca ggatcatcga gttctacagg gagatcgcgc gatacgtcgg
    47461 ctgcccgctg gaaaagacgc tcaactcctc caacgtcatc gatatcttcg tcctccgcaa
    47521 ggcattcggg aggtacgtgc tcccgtcgaa ggggtacgca ccggcagaag agttcgaggg
    47581 ggcaacggtc tttgacccga gccgcgggat ccgggagaac gtcgtcgtcc tcgacctcaa
    47641 gtcgctctac cccatggcca tgatgaccat caacgcgtct cccgagacca aggatccgag
    47701 gggagaactg agggcaccaa acggtgtgcg gttcaggaaa gagccggacg ggctgacacg
    47761 gagcatcatc cgcgaccttc tcgccgagag ggacgaaaag aaggccatgc ggaacaggta
    47821 ccccatcggg tcacccgagt acaccgtgta cgacatgcag cagaacgtca tcaaggtcat
    47881 catgaacacg tactacgggg tgagcgggta cgcgcggttc cggctctacg acagggagat
    47941 cggggctgcc gtgacctccg tcgggagggc aatcatcgag cacacgcgca gggtgatcga
    48001 gggtctcggt taccgcgtca tctacggtga tacggactcg tgcatggtgg aactcccggg
    48061 cctcgacctc ccggcgacca tcgcggaatc gagaaggatc gaggctgtcc tgaacgccag
    48121 ttacggcgag tttgcaaaaa gggaactgaa cgccgatgtc cactattttt ccatcaagtt
    48181 cgaaaaggtc taccgcaggt tcttccaggc gggcaggaag aagcggtatg ccgggcacct
    48241 cgtatggaag gaagggtcga tcgtcgacgg catcgatatc gtggggttcg agatccgccg
    48301 gagcgactac ccccagatca cgaaggccgt ccaggcacgg gtcatcgagc tcatcctcag
    48361 gggcgaaggg tacgatgccg tccggaagta cctgggagag gtcatcaggg atttccgggc
    48421 ggggaagttc ccgctcgacg agataggcat ccccggcggg ataggcaagg aactggggga
    48481 gtaccagaac gatgacgccc atgtccgggg agccagatac gcaaacgatt acctcggaat
    48541 ggacttttcc cgcgggagca agcccaaacg cgtgtacatc aggaacgtga cggggaagta
    48601 tcccaagacc gatgtgctct gcttcgagta cggcgaccag gtcccgcccg agttccaggt
    48661 cgactgggaa gtgatgatgg aaaagaccat taagcagccc atttcgcgga tcatcgaggc
    48721 actggggtgg tcatggagcg atatcgaccc ctcgcggacg acccttgccc agtgggggat
    48781 cgggtgacgg cacggagcgg tcctccggat ggagggggtg gtccgggagg cgtccgggtc
    48841 accatcccgc gggtcgtgat cgcagggacg cacagcgggt gcgggaagac gacggttgcg
    48901 cgggggatca tggaagccct cgttgcccgg ggatacacgg tccagccctt caaggtcggc
    48961 cccgatttca tcgaccccac gcaccattcg gctgtctgcg ggagggtctc gcgcaacctc
    49021 gaccccttca tgatgggcga agacggggtc agggagactt ttgcccgtgc ctgcaggggc
    49081 gctgacattg ccgtcatcga gggcgtgatg ggcatgttcg acggcctcga cggcacggac
    49141 tgtgccagca ccgcccacgt ctcgcgcatc ctctcctcgc cctgcatcct cgttgccgat
    49201 gtccacggga tgtcccggag cgttcatgcc ctgctgctcg gctacgcgac gttcgacccg
    49261 gcggtccggg tcgccggggt catcttcaac agggtcggca gcgaccgcca caggaccatc
    49321 atctcctccg ggctgcaggt cacctccctt ggatacatcc cgcggcaccc cgggctccgg
    49381 gtggagagcc gccacctggg actttggatg gcccacgaga ccgggtccga cgggacatgg
    49441 gggcggatca tcgaagaaca ctgcgatatc ggggggatcg tccgggtcgc gggggatgca
    49501 cctccgatcc cgatcgccgg accggtggaa cggcactttc ctcccccctc cgtgaggata
    49561 ggggtcgcga tggaccccgc gttctgcttt tactaccagg agaacctcga cctcctccgg
    49621 gcagccggtg ctgacctcgt cttcttctcg cccttgaacg atccgctgcc gcaggtcgat
    49681 gccgtgtatc tcggcggcgg ctacccggaa ctccacgcgg aagccctctc ccgggcagca
    49741 tgcaccgcgg cactccggaa ggccgcgtcc gacgggatgc cggtgctcgg cgagtgcggg
    49801 ggcctcctgt acctctgcga gtccctcggg gtggagcgga catttccgat ggcaggtatc
    49861 ctccctgcca cggcagagat gacgggaaaa ctccaggccc tcgactacgt cagcggcatg
    49921 tggtcggggg gtcccccgct tgctccctcc ggctctcccc tccggggcca cgagttccac
    49981 tactcggccg tctcctgcgg gtctgacgcc cggtttgcac tccggctctc ccggggcagg
    50041 gggatttcgg gcggcatgga cggcctgtac gagcacgggt cggtcgggac gtacgcccac
    50101 tcctcctttt cccctgcctt tgccggatcc ttcgtccggg ctgcacggga ctggcagcgg
    50161 gcctgaaaaa aaagggctgc tggtgccatt ccgggaaagg gcggtatcac ccccgcattt
    50221 tcccaccgtc ctgccggtga cgtcgccagg cccgggggga atcggggaat ccattatacc
    50281 tttccaaaga agagctctat cgcagagaag acaggcggtt gcccatgatg cggagcagga
    50341 aagtgaagga agggtaccag agggcgccca acaggtcgct cctccggtcc ctcggcgtga
    50401 cagaccgcga gatggatctc ccgttcatcg ggattgcaaa tgcctggaac gacatcgtcc
    50461 cgggacacgt gcacctgcgg atgctcgcca cgaaggtgag ggaaggtatc accgctgccg
    50521 ggggtgtgcc gttcgagttc ggggtgatag ggatctgcga cgggatcgcg atgggccacg
    50581 aggggatgcg gtattccctc ccgtcgcgcg agaatatcgc cgattccatc gaactgatgg
    50641 tcgagtccca tgccctcgac gggatcgtcc tgctcgggac gtgcgacaag atcgtgcccg
    50701 gcatgctgat ggctgcggca cggtgcaacg tgcctgcaat cgccgtgaca ggcggcccca
    50761 tgctccccgg gttcctcgag gggcgcaacc tctccctcat cgatgtcttc gagggcgtgg
    50821 ggagggtcgc cgccgggacg atgtccgcgg acgatctcca cgctctcgaa tgtgcggcaa
    50881 tgccgggatg cgggagttgc cagggactct acaccgcgaa cacgatggca tgcatgacgg
    50941 aggcgatggg gatgtccctc ccgggatgcg cagcagcgcc cgcggtcgac gcggcaaaac
    51001 tccggattgc acgcatgtcg ggggagcggg cagtcgggct cgtccgcgaa ggcagactgc
    51061 cgcgcaccat tatcacgagg gagagcctcc agaacgctat ccgggtcgac atggcactcg
    51121 ggggttccac gaataccgtc ctccacctca tggcgatcgc gtccgaagca gatgtcgatc
    51181 tctcgctcga gtcgttccgg aagatcgggg aagaggtccc gcacatctgt aacatgcagc
    51241 cctcgggacc ccactcgatg ctcgacctgt accggtcggg cgggattccg gccgtgctgc
    51301 acgagcttgc cggttacctg gaggatgcac cgacggtctc gggcaggagc atcatcgaga
    51361 tcgcccggga ggcacgcccg tggaaggggg ggatcatccg gccggtcaaa gaccctgtca
    51421 acccggcggg tggcctccgc atcctcttcg ggagccttgc tcccggcggc gcggtgatca
    51481 agtctgcagc ggtcgcaaag gagatgtgga cgcataccgg ccctgcccgc gtcttcgacg
    51541 gggaagacgc cgcgatgaag gcaatccttt cccgccagat cagggagggg gacgtcatcg
    51601 tcatccgcaa cgagggcccg gcaggagcgc ccgggatgcc ggagatgctc tcccccacat
    51661 ctgccatcgt cgggctcggg tacaggtccg ttgcgctcgt cacggacggc cgcttctcgg
    51721 gtgggacacg ggggccctgc atcgggcacg tgacaccgga agccgctgtc gggggaccga
    51781 taggcctcgt cagggagggt gaccggatcg caatcgacct ccatgcccgg acgctggatc
    51841 tcctcgttga cccaaaagaa ctggaacggc gcaggggaga atggaagcca ccgcaaaaac
    51901 ccctccgggg tgtgctcgca cggtacgcgg agatggtcgg gcaggcagac aggggtgccg
    51961 tgctccggaa ggaaaagtaa cttccgggga ggcaaaaaga acggagtgac cgggatgacg
    52021 gaaaaaacga catcgaaata cgagagggtt ctctgcaccc actgcgaggg ggcaggctgc
    52081 atctactgcg aaaagaccgg ctatgtcctc gtcctggcac ctgcccgccg gtgcaggcac
    52141 tgcgacgggg atggctgcat ctactgcggt ttcacgggat gggccggcct gaaagggcgg
    52201 tacgacgagt aaataccttt ttccttccac tccgctgtat cgtccgggtt accgggggag
    52261 aaacagcctt tttcctgacc cggcaaaatc ccttttaaaa aaagtgcgat tctctccggg
    52321 ggcggttttt ttgggatatg gcagggcccc gtatctccct tcctgttctc ctcacgtcgt
    52381 ggcggaatgg aaaaaacgag ttttcagtat tcctggagga acatcagggt tcctgcaatg
    52441 atatcgtgca ggccctgctt ataccgcgtg aacgcaggga tgaggaaccc gacgaagatc
    52501 gtcaggacgg agaggaagat gcacaggaac cggaggcttg cccgggcaaa cgtgatccgg
    52561 ttcccccgca tgtccgtgac agcgatgcgc atcaccatct tgcccagcgt cgcctggttc
    52621 gaagagctct cgaggtaggc aaagtacagc cacgggacga cgaggaggaa gagtccgaaa
    52681 aagatgatca cctgcgtggg aacgagcgca cggaccacgt tcccgtacgc atcggtccgg
    52741 ggcaggtgga ggtagtactg gtagagcatg acgattgctt ccgagagcgg gctgggcttc
    52801 tgggcaatcc atgaaaggat tgtgaccagg cccgcgacaa ggatatcgag gaaaagtaaa
    52861 aagacgatat cgagaaaacc tgcaccgatt ctcctcggga gactagcata tttcgctgtg
    52921 gtgatctctc ccacccgctt ccggaggaca gcccgcgggg gtgcgactct caggtccccg
    52981 ccgcaccact ggcagaatct tccatcggac tcggtctccc gcccgcactt gggacacaac
    53041 atcagtccag ctcctagaga ttaggttata atcgacgggt gtaacttcaa tttatcggat
    53101 tttttcccgg aatccgggga gtcatgaaaa gaggggattt tgcgggtccc cgggaccgat
    53161 gcaccgcctt ccgggggccg gctcctactc tcccggcccc cgtgcaggca cccggcgtgc
    53221 aaacgcctgc atcgcgaggg caaggacaag gcatgccccg gcggacaggc cgaggacagc
    53281 atgctgcaac ggcgtctctg tcccggtggc aagctgggca atcgtgttga gcgggtttcc
    53341 cgggaaggac agtgccgcga gcatgatgac gacgacgccc gtcgagaaga tgaactgggc
    53401 cgacgttctc tccctgtaaa agagggagac gatggccgca aggaggatga gagcgagaga
    53461 gaccgaaacg acgtgcagga tgatctgggg gatgtttgcg attgctatcc tgttcaaaga
    53521 gaggagggca agccacgttc ctgcctggag cgggacgagg acgaggcatg cggcaacttt
    53581 gccccagacg acctcggtca tcgtcatggg agtcgagagg agggtctcga gggtgtggtg
    53641 ctggtactct tcgcagatga ggtcaatgac gagggctgcg gagacaatcg ccggcatgaa
    53701 gaggaggagg ggtatcagca gaccgtagat gaactcgtag aatccgggac cgggccctgc
    53761 atccgggaac tcgagctttt caggtatcac gtcgaggcgt tctgcccgca gcatgcgcag
    53821 ggcctcctcg taggcgagga agacctcttt caatttcacg ttcacgatcg tggactggat
    53881 gtcgttctgg agcgtataga gggtgatctt gacgggttct tccgcatcgg ggggtgtcgg
    53941 aggcacgtac agcaccgccg cgagcttgcg ttccttcagc gcggcgactg ccgtcgaaag
    54001 atccattggg tagaccacga actgccggga ctcgcggagg agcctcgtca aatcgccctg
    54061 ttcccccacg tacccgacag ggtaccggac accctcgaac cgtgccaggg cagacgggtc
    54121 gtacatcgag gtgagcccga ccatgaggaa cgatgagaag agggctacga agagctggag
    54181 gaggatcgcg agcaggattg tcctctcgtg ggcaaggctt ccgaggtcct ttttcatgat
    54241 gagcaggata ttcctcgttt tcattcagat ccaccccagg atgatcgtgg cattgtacag
    54301 gcaatggatg agggttgcaa ggccaaggcc cgggagatac cccttccggc ccagtaccct
    54361 gacaaagacc gagaggacga gcacgcaggc aaagtggagg aggaacgggt atgcaaggga
    54421 cccgagcgtg agaaagagga tgctcccgaa gatgctctcg gtgatctggg ccagcgtgac
    54481 gaagaggagg agcttttcgg caaagaggaa ccctgcagcg gtcgcaaggg acccgagtgc
    54541 gacgaacgtc cacgataccc cggaccctcc ctcgaggatg aatgtcgcaa tgccgaccga
    54601 ttttgcaacc tcctcgacgc aggctgcagt cacgatgagg atgacgaggg agagcggcat
    54661 cgggaggttg aagacgagga cgaggaggag catctgcacc atgaagacga agggcacgag
    54721 gagtgcgctc acggcgaaga ccgagaggta cgggtgccgt gcggagaggg ctgccgagac
    54781 gaattcccgt atgcgggcaa cgatgccgga gagggaaaaa agccgttcct cacggaaatt
    54841 cacgatcccg acgtaaaaga ggattacgct cgtcaggaag aacagggatg tcgaatagat
    54901 gtactgggtc accgtgtagg tatctccctg cagggagagg acgatgaggg tgagagggga
    54961 gacgatgctg atgacgtgga cgtttgcaaa gatgctgggg aagaagaggt acgaggtcgc
    55021 gacggtcgag aaaaagatgg agatgaacga gagctccttg aaactccggg aaaccatgcc
    55081 tatcacgagg gcgcttgcca ggaagaagag gatgacgggg acgaggggca ggaggatcgt
    55141 gaggggtgcc cggatgtaaa gcgcgattcc cgtcgagatg gcaagcatcc ccgcaaggta
    55201 ggggagggcc tttccgacca cgatggcagc gccgcctgcc gggctcgaga ggaggacttc
    55261 ccccctccgc tcgatccgtt cctgcatgat gctcatcatg tagaactgcg aggagaagta
    55321 gagcgggaag atgaagagga agaccaggat gatcgagtcg aaggggagcg gcggggagag
    55381 ctgcgagggt atccggaagg acccgaacgg gctttccgac ccgaggagat ccgagtaccg
    55441 ggcaatctcg cccggctgtt cccgcgactg caggagaccc tgccggatct ccccgggcgg
    55501 gatcgggatg ccgggttcgg gtgtcgggac ctgttccacc ggcttttcgg ggacgggggg
    55561 ctgtcgcggg gtcgccactg ccgatatctg cctgccggac tgcgtcgccg agaaatcgag
    55621 ttcgctcctg atctcctgga catcaatcca gagaggatac gccgcaaaaa ggtcctgctg
    55681 ggcactgtaa acggaatcga ggtaatgctg gtagtccctc tgcagtgtcc ggagggcaga
    55741 cctcccccgc tcgctgtcat ggacgtagac gtcggtgccg gcgatgatga tgtcgaggga
    55801 cccgcggttc gaaaagaggg cgggggcatc cccgtaagag acgacgaacc gtgcatctcc
    55861 cccgaggatg ccggcgaccg ccgggttgtc cgtcccgagc cggtagatcc cgtcctggat
    55921 gtggaggccg cgttcggcgg tcagcccggt ggttgcaacg aggcagagca cgaggactat
    55981 ggcaaccggg agggtatttt tccccatcac gccaaaggtc cttttcacct cccaccgggc
    56041 cattgttgcc acgtgggaga ggaatacccg cacgtccacg attcttttcc cgtgaatggt
    56101 aggttcagta cctataatac cttgcaggtc aaggaatctg gacaacagga ccggctctct
    56161 catgataacg gcaagggacc tctccaaggt ttacgggaag acgacggtac tcagaaatat
    56221 cagctttgac cttgacgagg gcaggatact ggggatcatc gggcacaacg gtgcgggaaa
    56281 gaccacgctc ctcaagatac ttgccggcct catcgagccc tccggcgggc agctcgcgat
    56341 aaacgggaaa aacgccctga acaacccgga tggtatccgg caggtgatcg ggtacctccc
    56401 cgaggaatca cgcctctacg agacgatgag ggtgaacgag tacctcacct ttttcggcga
    56461 gatctacggg atggatcgca gctcgatccg ggcacggagc cgcgatctcc tggactggct
    56521 cgcactcgag gacaatggca agaagatcgg ggagttttcg aagggcatga agagaaaggc
    56581 ggcgatcgcc cggtcactca tccacgaccc gtccattctc atctacgacg aggcgacatc
    56641 gggcctcgac cccatgacgt cccgccacat catcgacctg ctgcgtgacc tgcgttcccg
    56701 gaaaaagacc atcgtgcttt cggcccacaa cctctaccag gtcgaggcca tctgcgacca
    56761 gatcctgatc ctgcgccggg gcgaacgcgt ggccctcgga actatctcgg aactgcggga
    56821 gatgtttgga tccgtctact atacggtctt tttcaccatc ggcgacccgg aacggatccg
    56881 ggggatcggc gacttttcac gtgacggcgg gtacttccgg gtcaatgccc cgagtgtcgg
    56941 cgagatgaac cgaatcacgc aggagatcgc ctccgcggga ggggccgtcg agcgcgtgga
    57001 gtcgcactac ccgagcctcg aggagatgct ggtgaagatc ggggcgtaat gacccggcat
    57061 tctcctgcct gttctctctc cccttcccgg tcgaccatgc aggaaaaagg tcgggctggc
    57121 gctggaaaac ggcatcgtca tcgcgggaat cctgcgccgg gcccggcatc tttcttccgt
    57181 ccctccggtt cccggaccgt gtcacggacc atgattccgg ggactccgga gagatgacgg
    57241 ttcggaagca ctttcccgct tcctgtacct gtcatgattc gggaaccggg ggaaaaatga
    57301 tttttccggg cagccgggtt acatttcccc gggatgcagg ggctgggagt cattgttcct
    57361 cctgcaatgt gcaggacaca cggtgcagga aagacttccc gaaagcttcg ggaatgtacc
    57421 ggttatggaa aaacagcatc aggagagaaa gcgggcctga agggatttga acccttgacc
    57481 tacggattaa gagtccgtcg ctcttccgaa ctaagctaca agcccgtgac cgattggccc
    57541 ttaaatatgg gtccgaatga agtataaatg ttttcgtttt cccgcatccc tttggcggga
    57601 aatgcacggg aatcgctttt tttagggcat gtccctgttg taaccttaat tatctctcgt
    57661 aatgacattc ttgcatgcca agggccggtg aatcgggaac cggggggaat gtccggtatg
    57721 cagtcctcgg gtgcgggacc acggggtacc atgtcgcgtt ggaactggct gcacggaaag
    57781 agagcgtcct tgtctgcgac atcgacgagt cgcgggtgcg ggaactgcgc gaacagaaat
    57841 tcgacgcggt ccggagggac atctcggatc ccggtttcct tgcgggtctt ccctctttcg
    57901 atgtggcgtt cgtcctctcc gggaacaacc aggtgaacac cactgcagtc aggacactcc
    57961 gccaggccct ccccggaacc cacatcatcg cccgtgcaac agaccccctc ggtgccggcc
    58021 agctcgggtc tgcgggagcc gacctcgtcc tctaccccca gcaggtggtc gcaagggccg
    58081 ccattcacca ggccgacaag gcccatgccg gcggcctcgc ccggaaactg cactccctcc
    58141 tcgccgggtg ggaggggacg ctcgcaatcg tcacccacaa caaccctgac ccggatgcca
    58201 tcgggagcgc catggcactc gccgcgattg cgaagagtgc caacccccag aaacttaagt
    58261 gccggatctt ttacgatggg atcatcgggc accaggagaa ccggacgatg gtcaacctcc
    58321 tggacatcag gatggaaaag ctcgacccgg aggcaataca ggactgctcc tacatcgccc
    58381 tcgtggacag cccgggcccg gggatgaaca actccctctc gccacggaca cgcgtctcca
    58441 tcatcatcga ccaccacaag gacgggcacg gtcaggatag tgcggctttt tccgatatcc
    58501 gcccgggaat gggtgcaacg gcaagcatca tctcccagta cctccaggaa ctggacatcc
    58561 cggtcgacaa gaacgtcgcg accggtctct tctacgggat ccggtccgac acccgtgaat
    58621 tccggaggaa cgtgacgccc caggacctcg cgaacgctgc gtttctcctc cccttaacgg
    58681 acggggacat cctcgaccag atcatgtccc cttcgctctc ccaggaaacg ctcgacgttc
    58741 tcgggaatgc aatcaagaac cggcacatcc agagcgggta cctcttctcg aacgtcggtt
    58801 acgtgcacaa ccgcgactcc ctgccccagg cagcggacct cctgatctcg ctcgagggtg
    58861 tcaacacggc cctcgtctac gggatcacgg atgacgcaat cgttatttca gcccggaaca
    58921 gggatatcag gctccacatc ggaaacgtcc tcgaggaggc attcggcgac atcggcgatg
    58981 cagggggcca cccgaacatg gcagccgcca ccatcccgct ctcctacttc cggcgcgtca
    59041 ggaacaagga gggactcctt gcactcgtca tggacccgct catcaggagg ttcatgggcc
    59101 tcgtcgggct cgaagcagag gagggccatg aagtttgagg agtgggagcc cgtctacagg
    59161 gagatcgtcg agtacttcgg gttcgaccgg aaagaagacg aacgggctgc cgagatcctc
    59221 gccggtctcc tcgaccgtga tgacctcccg ctcctcgccc ggttaatcgc ggggaaggat
    59281 gtctgcgtct gcggaaacgc ccctgccctt tcgcgcgaga tctccctcgt caccgggtgc
    59341 gttcttgccg ctgacgctgc agccctcgtc ctttatgccc atggcatccg gccggatgcg
    59401 atctttaccg acctcgacgg tgcccaggat gagttcatcg acatgaacag ggaaggcacg
    59461 atcattgtcg tgcatgccca cggcgacaac atcccgctcc ttcgctcctg ggtcccccgg
    59521 ttccccgggc ccgttgtcgg gacgacccag agccgccccc tgccccgcgt ccacaatttc
    59581 gggggattca ccgacgggga ccgtgcagtc tttgcggcgc aggccctcgg cgcctcgggc
    59641 atcacgctgc gcgggtttga cctcgacgac acccgcgtcg accggatgaa gagggcaaaa
    59701 ctcgcatggg cccggcgcct cctccggcag atccttccat gaagaagaag acggcattca
    59761 tcctcgacgg gtacgtggac gaaccggcat gcctcggcgt cccgcccttc atctccccgt
    59821 cgatccggac gcttgcgggc gtgctcaccg aacgggaatt cgagaccggg tacctgacga
    59881 tcgaccaggt gaggcaggac ccggcgacac tccgggtgct caacgagagt tccctcgtcg
    59941 tcatggttgc aggcgtgacc gtcccgggta agtacatggg cggcacaccc gcgaccctta
    60001 ccgagatcca ccagatcgga gctgcactct ccttgcccga aaaggtgctc gcggggccga
    60061 tagccttcgg gtactcgccg ggcggcggca ggaaggcaga gaaaggggca gtcccggggt
    60121 tcgatgcagt cctttcggga tcccctgcat ccgcgctgga caggtacctc tccggcaaag
    60181 agccgtccgg atcattcgat tacaaaaggg aagacccctg gagcgtttcg ggtgccggga
    60241 tcatcaggaa acacccccgg tttccccttg tgatgtgcga gctcgagacc gcccggggat
    60301 gcacgcggtt ccactcgggc gggtgctcgt tctgcacgga acccttctac ggcccccccg
    60361 tcttccggac ggtcgacgcg atagcccgcg aggtggatgc cctctcacgc gccggggcga
    60421 ggcacttccg gctcggtcgg cagcctgacc tcctcgtgta cggtgcatcg ccggcctccg
    60481 agttcccgtc tccggtcccc gaaaagatcg aagagctctt ctcgtgcgtg cgcagggcag
    60541 ctcccaccct cgcgaccctc catatcgata acgtcaaccc gggcacgatc gcccgccacc
    60601 cggacgagag ccgtgctgcg ctcgatgcaa tcgtttcctg ccacaccccc ggggacgttg
    60661 ctgcattcgg catggagacc gcggaccctg tcgtcatcga gcgcaacaac ctcaaggcac
    60721 agcccgacga ggtctttctc gcgatccgca tcgtgaacga ggccggtggg cacagggagg
    60781 agggcattcc ccacctgctt cccggtctca acttcgttgc cgggctcgcg ggggagactg
    60841 cacggacata cagtgagaac ctccggttcc tcgaccgcgt ccttgcctcc ggtctgctgg
    60901 tgcggagggt caacatcagg cagctgatgc cgtttgaggg gacacgggcg tataccgaga
    60961 acacgctcgg tgcgcacaaa tcgctctttg cctccttcaa ggcccgcgtc cgtgaaaagt
    61021 tcgacctccc gatgctgcag cgcgtctttc ccgtcggaac gatcctccgg aaccttgtca
    61081 tcgaggaaga gggcatacct tcgtttggcc gccagatggg gtcgtacccc atcctcgccg
    61141 gcatacccct ccggctgccg cttctcaccg tcctcgacgc cgtggtggtc gaccacggga
    61201 tgcgatccgt cacggccctt cccgtcccca tcgctatcaa caccctgccc gcccgggcac
    61261 tctcctggat accgggggtc ggaaaacagc gtgctgcccg gatagcaggg gcaaggccct
    61321 tccgcgacat cggggagctg agggccgttg ccgggccgct ccccctcgac cacctcttct
    61381 cgttctccta gatctcgcgc aactcgatga ccttgaggat atcggtcttt gtcacgatgc
    61441 cgaccagctg gtcatcgacg gtgacgggga tgcgcccgat gttctttgcg gacatcgtgc
    61501 gcagggcatc gatgaccggt gccgacggcg gaagcgtgat gatgtccctc gtcatgacgt
    61561 cccggacctg cattgcctcg cggtcaatgg ggctgaccct gtggaggtcg gcaagggtga
    61621 ccatacctgc gaggtggccc ctctcgacca cgggaaagcc caggtgcttt gttgcataca
    61681 tgaggtcgat gacctcccgg acaggtgtct ggggggggac cgtcatcacc gggcttgaca
    61741 tgatatcgcc cacggaaacg tccttgagga gaaacgtgta ccggattgcg gccgattcct
    61801 gcgttgcacc gatgtagatg aaaaacgcga tcaggatcag gatgggagaa aagagcagga
    61861 cccccacgat cccgaagatg accgcaaacg cctttcccac gtccgctgca atcctcgtcg
    61921 cgtcgggaag gggcatccgt gtcgcgaggt atgcccggag cacgcgcccg ccgtccatcg
    61981 ggaatgcagg caggaggttg aacgcgaaca ggaacacgtt cagcagcccc aggtacgaga
    62041 acgcaaagac cagcaggccg gagaggggtc cggcgaaacc cgcaagggta acggcataca
    62101 tgagggcgat gaaaaggaga ccggtggcga ggctcgtcag gggaccgacg agtgccatcg
    62161 ggagctcgac gcggggatcg ggagcgctgt cctccatgga agagactccg ccaaagacga
    62221 ggagagtgat gctgtggatg ggaactccct tcctctttgc aacgatgcag tgcgcgatct
    62281 cgtggagaag gacaccggca aagagcccga gtgcaacgaa agcgccgagg atgtacgggt
    62341 ttaatcccgg aaggaggtac gtcgtgtcga tcgggacgcc gaacgtattc gagagcaggt
    62401 cgacggtaag gaggatctgg gtgccgatta tccatgcaaa tacagggatg atgatcagaa
    62461 atgtccagtg gatcaggatg ggaatgccaa aaatggaacc tattttgaaa gacccgttca
    62521 ttaaaggagt atctttttaa ctatcatggt atatatcttc catgattagg atgagaaccc
    62581 agattacgga gttgtttgga ctgaatattt acactgaaaa gagtgtcttc gtgggtgaag
    62641 tggaagacgt catcctcgat atcgagggca agaagatgga atcccttgtc gtgggcaagc
    62701 tcaaccagga tctcgtggac atcaagaatt acaagggtct caagattccc ttccgcatca
    62761 tcaggagtat cggggacatc gtgatcatcc gccacctccc cggtgcattc aagacgggtg
    62821 ccccggcgga gaatccccgg tagaagcacc gggcatggct cttttcccgc cggaccagac
    62881 acgctttctc cccccttttt atgcgacacc gtgaactcta cagcaacctc gtggcactcc
    62941 cgccgctttt catcaggctg gacggccgga gtttccaccg gttcgcagag tcctgggcgc
    63001 tggagcgccc cttcgacgag aggtttgcca acgcaatggc acgcgtcggg gaacggctca
    63061 tcactgaaag cggtctttcc cccgaccttg ccttcacgtt ctccgacgag atcaacctct
    63121 acttctcgcg gctccccttc aacgggcggg tggaaaagct cgattccgtg actgcctcat
    63181 tcgcggcaag tgccctcacg attgcaatgg agagcaccga acccgtctct ttcgatgccc
    63241 ggatcatcca tgtcacaccc gaggttgccc ccgagtacct gatccacagg cagggcgagg
    63301 catggaggaa ccacatgaac gcgtactgcc agtacatcct tgtccgggaa ggtatgacca
    63361 ggaaggaggc agcggccttc ctgaagggca ggccggcccg cgaaatgcac gaggttgctt
    63421 tctcccgcgg tgtcaacctc gcagagaccc cggcctggca gcggaggggc atccttgtca
    63481 ggaagcggga gagaaaagtg aaaggtttca acccccgtgc cgggaaggtc gaggagagct
    63541 accggagcga ggtcgtcacg gatcggaacc tgcccgtctt tgcctcgccg gagggccgtg
    63601 ccctcctctc ctcaatcctg cgcagcccgt gaaagggaga gggtcatgct gaccccctcg
    63661 acgtcccagt cccgcacaag gtcagcatcc tttcctgccg gggactggtc gcatgaaaaa
    63721 tccagggaga cggccctgat ctcgtccatg atcccctttt tccatgtctc tgcgaccatc
    63781 ctgcagatcc tttcgtcggg gatgcgggcc gttgcgcgga cgaaatcctc gacccggagg
    63841 tccagctgcc gccgcatctc ctggaacctc cggatgatct cgcgtgcata cccctcggcc
    63901 tcgaggtcgg gggaaagcgt ggtgtcgacg tacactgtcc cgccctgcat cggtgcggaa
    63961 cagatccctt ccggcagttg ctcgacaaac gtgacctgcc cgggtgtaac ctcgtacctc
    64021 gcgttcccgt cggagaggac aaagactccc ccggattcga gggctgcctt catggcgttt
    64081 ccatccgctg cgaggatgag ctcgcgcaca cgcggtgcgt tcttcccgaa cgcgggaccg
    64141 agtgctttca tgaccggctc ggccttccac ccgatgcggt cccagtgacc aaggactgcg
    64201 cggacttccc gggcgtttgc cctttcccgg cagatggggg caagtgtccc gatggcaccg
    64261 gcgataccgg gactgtccgt gacgacgacg cattccttca ccggccagcg gagtttccgt
    64321 ttccctgcct gccgtgcatt cgcctgtgcc tcgtcaaagg accggacagc ctccatcatc
    64381 tcctcgagct gccggtcgac gagtgcgggg tctcctttct gccacgggag catgtggacg
    64441 ctctgcgggt ccttttcgag tttcatgttc cggtacatcg cctcggtgac gtgggggacg
    64501 aagggtgctg caagggcgag gaggacccgc attacgtagt acatcgtctc gtatgcagcg
    64561 gtcttttccg gtgattcgcc ctcgagccac atcctctcgc ggacaagctg gacgtaccac
    64621 cgcgagaggt cctcgagcac gaactgaacg agggcacgcg atgcccggtg gaggttgcac
    64681 gaggagatat ccccggtcac ctgggctgca aggttgttga cacgcgagac gatccaccgg
    64741 tccacgggtt ccagggaaga gaagttctcc ctcacgtacg tcccttccca catcccgccc
    64801 cgtgacgaag gttcgaaccg gtcaaggatc atgtagggga gggggaaccg gtacacgttc
    64861 cagaggatgt tgatggcccg tgcggtgttc ctgacaccct cccagttgaa ccggaggtcg
    64921 tcccacggcg cattctgcga caggacgtag aggcgcagga catctgcccc ctgcgtcctg
    64981 atgacctcct cgggtgtgac gacgttgccg aggctcttgc tcatcttccg cccctctgca
    65041 tcgagcgcaa acccgtgcat gaggacgctc ctgtaggggg ccttcccgaa cgcgatcacg
    65101 ctcgccccga gctggctgta gaaccagccc cgtgtctggt cctgcccctc cgtgatgaaa
    65161 tctgccggcc acaggcgctc gaaatcgtcc ttcctgcccg ggaacccgag ggtcgcccac
    65221 gaggccacgg ccgagtcgaa ccagacatcg aagatgtctt ccacgcggcg catcaccccg
    65281 ccgcaggcac acgggatctc gacctggtcg acccacgggc ggtgcggatc ggtgaccgtt
    65341 gtcccgcttg cctcttcgag ttcccggaac gtcccgatga cccggtacgt cccgcacgat
    65401 ccgcatgtcc atatcggtat cgggatgccc cagtacctct ggcgcgagat gcaccagtcg
    65461 cgggcctcct tgatccagtc gtggaaacgt gcgctcccgg cccagtcggg gtaccatgtc
    65521 accttcgcga cctcttcgag catccggtcc cgcatctggg atgctttgag gaaccactgc
    65581 tccgttgccc tgaagatgat gggggtcttg cagcgccagc agtgcccgta acggtggaca
    65641 acgctctcct gagcgagcag gtgggaaccg agatctgcca tgaccacggg gtccgcttcc
    65701 ttgacaaaga ggtttgcata cttccctccc tgcccggtga accggccgtg gatgtcaacc
    65761 gggcagagga tctcgagtcc ctcgcggcac ccgagcacgt agtcgtccca cccgtggccg
    65821 ggtgcgatgt gcacgatacc ggtgttttcc ggcgcaacga agtcggcggg gacgacacgg
    65881 tgccggatct gtctctgggc cgggacctgg tccctgaggg gagacgtata cgagagagcc
    65941 tgcatgtccg ttcccgggca tgtcgaaagg actgtgtagt cctggtacct ccctttcttc
    66001 aggacgtttt cgatgagttc cctggccatc cagaggatct ccttcctgcc acccttcgtg
    66061 gcttcgaccc gggcataggt aaagtccggg ttgaccgcca ctgcaacgtt ggcaggaagc
    66121 gtccaggggg tcgtcgtcca tatcacgatg tactcgttct ccctgccctc gaccgggaac
    66181 ttgacgaaga tggaggggtc cgtctcgtcc cagtactcga cctcggcatc ggcaatcgca
    66241 gtggcacacc ggggacacca gttgacaacg cggaaaccac gctcgagcat cccttcctcg
    66301 tccgccctcc ggagggtcca ccacgccgcc tcgatgtagc cggggtgcat cgtctggtac
    66361 gggtcatcga agtcgagcca tgccccgagc cggaggaact gcctgctcat gacgtccttg
    66421 ttggttgcgg caaattccct gcaatgctcg atgaacttcc cgatcccgaa gcgctcgatg
    66481 tccttcttcg aggagaaacc gagtttctgc tcgaccctca cctcgatggg cagcccgtgc
    66541 atgtcgtagc ctgcccgcgc aatcacgttc ctgccgcaca tccggtggta ccggaggatg
    66601 cagtccttga tgatcttgtt ccaggccgtc cccaggtgga tgtgcccggt cgtgtagggg
    66661 gggccgtcga cgaagaaaaa gtcttcgccg cctttgcgca tctcttcgac ccgtctgaat
    66721 atgttttcct ccgtccagaa ggcctggacg gcctcctcga tctcgcctgc ctggtaactg
    66781 ctcttttcct ccttcatgga tcagaccccc aaaaaacccg gctgcacccc gggaacagga
    66841 cgcgtcccgg gatggtgtcc cttcccccgg tgtaccacgc ggggtgacgg gcaggaagta
    66901 actcgcaaaa tacatcggtt ttcccgcggg taacagccgg catcacgggc cggggacccg
    66961 cggggattga cagtgcacgt cctttcaggg aataaaacga tctgtcatgg aattattcca
    67021 ccacgaagat atacatggga cagcagtcta taaaaagccc ctcgtttctt ttgggttgtg
    67081 cgaccgggcc gcagcccacc ggaaagacca ttaatgccgc ccggacgaaa atctcctcta
    67141 tggatagcac aggggacagg caggatccgg gcctcaccgg ccatgggtgt atcgtcggcg
    67201 gagaagagcg tttcacgggg gatatcagga ccgtccggtt tcctttcacg ggagaacctt
    67261 tcgcatgcgt gcaccaggca cgcgaaaagg atctcgacga tgccgttgca tcggcagccc
    67321 gtggtttttc cgcgacccgc gagctttccg gtgcggagag gtaccgcatc ctcatggccc
    67381 tctccgattt ggtccggaag gaatcggaaa accttgcccg ggtgctcgtc atggaagggg
    67441 gaaagacgat cacctttgcc cggtcagagg tccagcgcgc catcgagacg ctgcgtgtat
    67501 ctgcagaaga ggcaaagcgg cttggcggcg aggtgattcc cctcgactgg acacccggca
    67561 acgagaagag gtttgggata acgcggcgca tgcctctcgg cgtcgtggtg gggattgtcc
    67621 cgttcaactt ccccctcaac ctcgcctgcc acaagattgg gccggctgtc gcttccggaa
    67681 atgcagtcgt cctcaaaccg gcaacggcaa caccggtctc cgctctcatg ctgggaaaaa
    67741 tgctcctttc tgccgggttt cccgcccctg ccctcagtgt cgtcccctgc ccgggcgggc
    67801 gtgcggagag gcttgttcag gacgaccgcg tgtcattcat ctcgttcacg gggagcgctg
    67861 aggtcgggtg ggctctccgt ctgaaggcag ggagaaagag ggtctcgctc gagctcgggg
    67921 ggagtgcgcc ggtcatcgtc cacgaagacg cagacatcgc gtttgccgca tcccggatcg
    67981 tgcagggcgg gttttcaaac gccgggcagg tctgtatctc cgtccagaga gtccttgtcc
    68041 acgaggcggt acacgaccag gtatgccgcg aagtatgccg gggtgcaaaa cggctggtca
    68101 ccggtgaccc gcggcgcggg gagaccaccg tcgggcccat gatcagcagg gaagcagttg
    68161 aaaaagccct cgggatggtc cgggaagcac aggcacaggg tgcacaagtc gtgaccggag
    68221 ggcgtgccga cgggacgctg atgtacccga cggtcgtttc cggggtgaca cccggaatga
    68281 gactcttccg ggaagaggtt tttgccccgg tcgttgccat ctgctcctac cgcgactttt
    68341 ccgaggctct ctcccttgcc aacgccactc cttacgggtt acagatggga ctctttaccc
    68401 gtgacatcaa ccggatactc gaagcttttg gggagggtga gttcgggggt atcatggtca
    68461 atgacgtccc gacgttccgg gtcgaccaca tgccgtacgg gggggagaag gcatcgggac
    68521 tcgggaggga aggtccccgg tacgccatcg aagagatgac ggtgctccgt ctgctctctt
    68581 tcaacccgga ggggggttcc cggtgaccgg ccctgcccgg cccgtccaga tcgccgtgat
    68641 cggggcaggt gactgcagca gggaggaaga gagagccgcc ggggagatcg ggagaaccct
    68701 tgcagaaaac ggggccatcc tcatctcggg cggcatgtcg ggggtgatgg aggcgtcctg
    68761 ccgcggtgct gcatcgtccg gcgggatcgc ggtcgggatt ctcccgggca cgggggacgg
    68821 aaacccttac ctctccgtcc ggatcaggac ggggatgtcc cacgcacgga actacctcgt
    68881 ggtcgagagt gcggatgccg ttatcgctgt cggcggggga tacgggaccc tgtcagagat
    68941 agccttcgca ctgaaggcag gaaaaccggt ctatgggtac cgcacgtggg atatcccggg
    69001 ggtctgtgcc tgcccgaccc cgcaggatgc ctgttttaag gcactctccg ccgctcaccg
    69061 gtgatttccg tcctgtatcc ccccatcttt tcgagggccg tgcgaaattc cggggacgag
    69121 actgcatcca cgagtgcctg caccctccgg tcgtccagtg cagagaccgg gatggcaagt
    69181 tcgtacctct cgcttgccac tgggacaaag gagagcccga acgcccgtgc ggcagaagca
    69241 acgcccatcc ctgcctcggc ctcgccgctc cggaccgcga gggcaacggc cgtgtgggtc
    69301 gggacctccc ggtcataccc gggaatgtcc cgcggcgaaa tccccctcct gtgcagctcg
    69361 tggtcaagga gcatccgtgt gcccgagccc ttctgccggt tgatgaatct tttcccgggc
    69421 aggtcatcga gcgagagccc ggttttcgac atgataccct gctccctgcc ggcgacgcag
    69481 accagttcga ttccggttcc cggcaggtac ttcgcgatga acggcacgtt gtagtcgccg
    69541 ttttcggcga ggaggtgcat gggcgccgca tggcagtcac ccttgcgaag ggcaaggagc
    69601 ccgcccatgc tcccggcatg ggccgagaag agcccggttc cccttgcgtt caggatgtcc
    69661 gcgagcacat cgagggcagg gtcgtggctg cccgtgacga caatcgcaga cgccgccctg
    69721 tccatgccct ccgaaagccg gacccgtacc tgttcacccg cggaaaaccc ttcaaccgat
    69781 gcggggatgc agatgtaccc gttcgaccgg acggcactca tctgtacccc cgatccccgg
    69841 gagaggggtg ttgcaaccca ctgcccgccg acgttcccgc aggatacgag cacgaactcg
    69901 tccactcctg cctcggagtg gagagtcgct gtcaggcggg catcgatctc cgcacagcca
    69961 tagaccggta tgcccgatac ggagaggaga taactgacga gttcgcggag caccgtgagg
    70021 gccgagagcg ggtagccggg catcccgatg acgggaattt ttcccacggc accgatgatg
    70081 acgggttttc ccggcttgat ggcaacgcca tggacaacga ccctgcccac gtccgcgagg
    70141 acgtccgccg tgtaatccct tgtccccgca gatgaaccgg ccgagacgat gacgagatcg
    70201 ttctcccggg cggccgagag gatcgcctcg cgtatgagag gggggtcatc cctcaccgga
    70261 ggataccgcg tgcattcgcc gccatgacct gccagccatg cttccgcgag gcgggtattg
    70321 ctctcgacca cctggcccct gcccggtctc gtccccgggg gaacaagttc gcttccggtc
    70381 gggatgagcc ccgcacggaa gtaccggacc gggacttccg tgatcccgta cgtcgcgagg
    70441 gccccgatgt cctggggacg tatgcggtga ccggatggga gtatcatctc ggactcggcg
    70501 atgtcttcgc cgggaggccg gacgtgctgc cagggacttg cgggtctccg gatcaggaat
    70561 gcatcaccct ccttccagac ctcctcgatc atgatgaccg catcgtaccc gggaggaacg
    70621 acgtttcccg tgttgaccaa aacggcatcc ttcaggatga ccggggactg ctccgatgcc
    70681 ccggacgtgt cggcgctccg gacggcaatc ccgtccattg cggcaatgtg ttccccggga
    70741 acggagtacg gggcaaagag ggcccgtgcc gtgacccgcc cgcatgcctc catgaggggc
    70801 acggacttct ccctgcaggg cacaggcgtc cctgcaaggg cttcctttgc ttcctggagc
    70861 gaaacaaccg agaggtacct cttcaccaca gcagcacccc gacggtcgtc ccggcctcga
    70921 gcccctcgct ccctgccggg acacggacca tcccgtcgga ctccgcgagc gtgttgagga
    70981 gccctgactt cccgaagagg gggactgccc gcccgccttc gagccgcacc cggacgtagt
    71041 cttccctgcc ccgggcagac gggatgttct ctgcaaggac tgcgaggacc gtgttttcga
    71101 cgcgcgatgt ttctccggac agtgccgcga ggagggggcg tgcgaccctg tcgagaacga
    71161 cgagtgcgga ggccgggtga ccggggagcc cgataaccgg tttttccccg cacctgccga
    71221 tgatggtcgg ttttcccggc gagatggcaa taccgtggac gaggacctgg cccagttcgc
    71281 cgatgaggtc agccgtgagg tcgcgctcgt ccttggagct gcctcccgag aggaagaccg
    71341 catcgttttc ggcaagggcc ctccggagtg ccagggcaag cgcttcccga tcgtccggga
    71401 cgataccata ggtcttttcc cggcaaccgc acctccggag gtacgctgct atcatcggcc
    71461 cgttgctgtc cctcaccttt ccctctcccg ggacgtcatg gacactgacg agctcgtttc
    71521 ccgtggatat cacgccgacg cggggcatcc ggaagacggg gacggtcggg cagccgatgg
    71581 ctgcaaggac cccgcagtct gcaggccgga gcctccgacc ggcacgcagc gcgggcctgt
    71641 cccgagagaa gtcctctccc ctgcggacga tgttctcccc gattcccacc ggtcttttga
    71701 cgaggacctg gtccccgatg acctcgcagt cctcgaccat cacgacggca tcggcaccgg
    71761 ggggaacggc tccgccggtc gggacgtaca cgcaatggcc ctccctgact tcggatttcg
    71821 ccccttcccc catcctgacg gtggcaagga gcgtcagaaa ggaggggatc gactccccgg
    71881 caccggtcgt atccgatgcg acgacggcat agccgtcgac cacggagcga tcgaaacccg
    71941 ggatatcgag gtcagggtat acatcccggg cgagcaccct gccgaccgct tcttcgagag
    72001 gcacatcctc cggggaaagg gggcgtgcga tacgtgccgc gatgccgatt gcctccccca
    72061 ccggaaccgt tttcagaaaa aggctcattt aaagcagccc agctggcatg cccgtatctt
    72121 gatgccatgc gcattgcagt accgggctat gtccatcttc gggatgccat acttctccga
    72181 tagtgcaaat gcctggggac acttgatctc cctctcgatt ccttcggctt cgaaagcctt
    72241 ccgtactttt tcttcgtcca tcattccata tatgggacag gcggggtata aaaaaaattg
    72301 acatttgccc tgatgttaag ctaatcatcc taactccggt ccggagcgcg gttcccgggc
    72361 agggcaggca ggatcaagga acccttcata ctccggatgg gttccggcct tcacacgcga
    72421 gaaaacaaaa gaaaaaaatg cggacaggcc ccggaacgga gccgtgcccg ccggttcctt
    72481 tactccttcc tccgcacggc gaggagaccg gccgtaccga cagcgacgag gacaaggatg
    72541 gtcaagaggg gtgacttcgt gggagtcggc gtgggggcag ggttgagagt tgcgtaaaga
    72601 tcgacggtct cacccttccc gggataccgg tcgatcgttc ccgtgtatgg ctggtacccc
    72661 gccatcgtca cggtgtacgt cttaaacggt gttgcagtcg tgtagacctg gaccgtcagg
    72721 atgccatttg tgatggttcc ctggggagtg ttgtcgaacg acacggatgc accatcgaca
    72781 ttgcagtgga ctgcaaacca cccgatgtcc ccgccgatga gcgggggctg ggtcggctgc
    72841 gtgggattca gggtcgcgta caggtcaaaa gtctcccctt tgccgggaac gccggggatg
    72901 gaatcgctga aggtcgtgta accctctttc cggacggaat acgtcttgta gggtgtcccg
    72961 gtggtataga ccgggacatt caggacgttg ccctggatgt ctcccttgta ttcgccatca
    73021 aagtagacgc ttgcaccgtc cacgttgcag tgaacggcat accatgcctg gtctcccccg
    73081 ataaggggct ctgcaccggc ggggaggact gcaaggaaga accctgcgac aagaacgccc
    73141 atgagaatgc ggaatgatac tttcatttga atcactttga atccggttgc ctttccctat
    73201 gagatttatt cgtttaaaag ggattcggaa aggtagtgaa ggaaaggaca gttttcccgc
    73261 aggagaagcg gtacctgtcc ggaaaaaggg agaggaaaaa cggggaggtt atgtcaccgt
    73321 gatgtaaccc gttttttcca ctttgtgggt aaccggtatt ttatcgggac ccatcgtcca
    73381 gactgtgaga gtgacgttat acgtcccggg tttccggtac gtgtgggtgg cattctgctg
    73441 cgtcgccatg aagccgtcgc cgaaactgta tttccagagg atcggtttta ccgtggacat
    73501 gccggtaaaa gagaccttca gcggggcttt cccggacagg gggttcccgt gaaatcgatt
    73561 tctacttcgg gttccgtttt cttctctacc gtgatgaagg cgggacggat agtcgttgca
    73621 ttcaccattt tcctgccgtc catcttccag attgtgaggc tgaccgtgta attgccggga
    73681 cggttatacg tatggaccgg gtttttactc atggacatga aaccgtcccc gaaccggtac
    73741 aggtaacggg tcgggttccc cgttgaatgg tcggtaaact gaacggtcaa tggagatacg
    73801 cccacggaag gactggcatc gaaatcctca cggaatgatg gtgacgggtc tatctcatag
    73861 gatgacacag gtgcaaggag cgggtaccga tccgtgttgt tcactctcac gggatacggt
    73921 gtggtcccca cgccatttcc atccgtgtcc gtccccgcat accagttcca gtagttcccg
    73981 agatacccct taaacgtctt tcccccataa ttgtagaaca ccgggtcttc agtgttgaac
    74041 gtgttgtcct taaaaggcgt tcctgtttca ggtaccaggg gagcagtaag gtttccagag
    74101 gagggaagcc cccatgcaag aggtgtgccg ggggaatcag gcataaacca cccgggcgga
    74161 tggaaaattc cggtaatggc gggaggttct tcgactgacc tgaaattgtt caggtagatg
    74221 taattggagt acacgtaggt atcgggcaag ccgataaaaa acgcgatctt ttccgctgat
    74281 atgttattat tgattacccg gtttgactta gccggtacgg ggaggtccgg cgctaattcg
    74341 ataccatacg tgcaattgtt catggtgtta tccacaaaaa tattcatctc gccaccacat
    74401 aggaacacgc tctggtacac agaagagact tcattattcc agaaatggat tctatcagaa
    74461 tccaagataa atataccaca atccctaata tcgagggagg ggtcattgcc gacgatcctg
    74521 ttaccggtta cagaaatctc tcttccatgt tcatattcga aactgaaccc gatcttgttc
    74581 ccttcgagga tattgttcga gaaccagaca tgctcgtttt ccgatgccgc tgcaaggcct
    74641 ctggaattcc caaccgcgtg gtttccggtc agatttacaa aggacgacac aatgaccccc
    74701 gccccgtaca tggcaccttc gagcctgtta ctcacaattt ttgcattctc cacagcgctg
    74761 acgaggatgt tctggtaaag gttattcgag atggaattgt ccctgatcgt gatgtgttcc
    74821 ccaccccgga gaaggattcc aaatccgttc cggcttgcca taaccatatc atggaccgtg
    74881 atattcctgc accccacgag gtagatagtt gcatattccg aacccgtgat atccctgtcc
    74941 tgaacaccct ccaggtagag gacaggcagg ccatcgacag tgttcgagag cgtgacagtg
    75001 ttgcccggtg cactattacc atcatgatat gagaaacctg catagttatc ctccataatg
    75061 ttcccctcaa ccagtgactc agacatcccg tcaatgaaaa atccaactcc accgttgtgg
    75121 atgaatcggt tattccggat agtcgcattt tcaagccacg cgaagtaacc cccggcactg
    75181 ccggcatctc ccggctgctc aaattcaacg tacgcattgt cctgtatcag gtttccttcc
    75241 acttccgcgt ttccgagatc atcaaagaaa cagaggcccg tctccttgtt atgtatgatc
    75301 gtattattcc ggcaggagaa tcttccctcg gacgaatcta cgtagatgcc aaaggtgtta
    75361 tcgtgcacgg tattttccga gcaggtagta agagatgggt ggtcgagata aatcccttcc
    75421 acgtcgttct ggaagacttc gtttcctgtt accctgaagc ccgaagtgaa ggagccatat
    75481 attcctacct ggcagtcagt gactttgcag gaatcaaccg taacatcggt tatatggaat
    75541 gccccaattc catagcccgg ccatttttcg tcataaggca tatatcgggc acttcctgtg
    75601 acctggatat ccttaagaac caccccatca gcaacgatcg tcaccccgtt tcccgaatag
    75661 cttccgttga tcacagtggt gctggcgtcc tcgccctcta tagtgagtgt cttgttgacc
    75721 acaatatgct cgtggtattc acctgccatg acgaggatag tatctccctc ggacgcggca
    75781 ttgatcgcct cctggatggt cgtgaaattg cagccggacg ggcagactgt ccatgtctct
    75841 gccatcgccg gcataacaag aagcatcgtc attacaattg caacagggaa aataaagcgg
    75901 acccctgaat ttaccgttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    75961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnca
    76021 tcgtcattac aattgcaaca gggaaaataa agcggacccc tgaatttacc gttacactcg
    76081 ttgccacctt tcgtgccata cacccgcctc ccggtaagaa agcggatgtg aattgattta
    76141 tgttctggtt tatataattt cccgcatccg tgcccctgac cccctcagga atgttgaaga
    76201 tggatggaag ggcacgacgg ggatgtcact tatctgagaa ttcgcggcag gcaagcagcg
    76261 cgagaaacgg gagagcgagt atccagtagt gcagatactg ccggatcagg atggtcaaaa
    76321 gaaacaccag tgccaataat ccgattacac gttcttcagg agtgcggaat cccctcttta
    76381 tactgctcgc gatggcaaag aggagtgttg ggaaaaccat cacgatactc gcgagcaggt
    76441 ttactgcaag accaataacg ctcgttgcgt gataatccgg gactccaacg agggtaccct
    76501 gcaggtacat cggtccgata ccgaatgtcc ataccagtgc attcagggca gccgccggac
    76561 catagatgac agaaaacata ccaaatatcc cggcaatcac tgcaaaagca ggcagcaaga
    76621 gtgtatacca gtgactttcc tttctgctgt tcatcaggta gaggaatgga atgagagcaa
    76681 ggactgcata ctgcttgtag ccgcacgcaa ggcccacgag aatccctgca ggaacatagc
    76741 ggctttcccg tgccatgatg aacccgaata acaggagggc cacaacgaac tgttcgctga
    76801 aaaggaagaa tccctgcacg aggactgaag caacgaggaa gagcattccc gctgaataac
    76861 ccgcaatctc cccgtaatcg tccttcccta ttttccggat catcaatgca gagaggacat
    76921 tgagaaaaga tatcacgatg atatcggctg aacctggagg aaagagagaa tcaatggcag
    76981 caacagtgaa ataaagcagg ggtggttttt aatcgacgaa atcaacgtag ggtgtcaggc
    77041 cggatacgat aacttctgcc atgtaatgga atcgttttcc atccaccccg gtccatgcac
    77101 ctgttgcatc gtttgcgagg gtaaccatta taacggcgat aattgccgca acgagggaat
    77161 aagaaaggat tacagctatc cacgtgacaa ggtgctggtg cgtgtgaaac agataccaaa
    77221 tatctttcct atggaaaata ttttcacttc caacggatta ttatggactt ttggtatggc
    77281 ctgatatggt tgccctgcga tagcatttga atgaggcact actaaaacac taccccgttc
    77341 gagggagtcc ccaggcttat cgataattca accatcccat ggtgaatgaa cccgggacga
    77401 tcccgaatga accattccgg cggaaaaccc gatattccct tattggaccc aatgaatttt
    77461 caggacgaga ttcgatctgt aacctgccgt cccggttcag aatgggaaaa taaaaaaggg
    77521 ccggaaagct ccagcacccc cgccgttaca cgggggtgct cggtcagcct tgctccttta
    77581 tgcatgaaaa acaagagaat gtaaacagga atgaagatcg ccctcgtcag ttccctccgg
    77641 gaccccggtg gcagcaccat ccacgatgcc ctcctctctc tcctcggtga cccccacgag
    77701 gcgtatcccc tggaacggca cgacctcgtc caccacaggg tggaggaccg gctcatctac
    77761 aaggaccata tcgaccggga gatcgatgca gacctcatca tcttcctctc ccgccactca
    77821 tcggtcaacc ctgttccggt cctgaccgtc cacgtcaccg gcaacatctc atctgccgac
    77881 ttcggcggca gggaacgttc ccttgcccct gccgccccgg cctggatgca tgcggtcctg
    77941 cgggaactat cgaagaatgc cccgcacccc taccgcgtag catacgaggt gacccaccac
    78001 ggccccacgg aactctccac cccttccttc tttgccgagg tcggcagcac ggagcgggaa
    78061 tggaggcaca gggcagcggg actcgcggtg gcacggagtg tgctctctgc cgaccccgtg
    78121 gactgtattc ccctgatcgg gtttggcggc acgcactatg ctgcccggca gacccacatc
    78181 gcactcacga cgaggggggc attcgggcac attgcgcatt cacgggaggt gcccacgctc
    78241 gatgccggga ttatccgccg gatgcgggag aagtccgggg ccgttgcagc ctgcatcgac
    78301 cggaaatcac tttcgtcggg agaactggcg actctccagg agatgcttgc acaggaaggc
    78361 atcccgatcg tcacggagga tcacctcgcc cacatcggga atctttcgtg ggattcgtac
    78421 caaaaaatcc tctcccttgc cggggacatc gtcccggggg gacgagtcac cctctgcggg
    78481 gaatggccgg acggcactcc cgtcgtcatc gaactcttcc cggacctcct cgaagaaacc
    78541 ctgcgttgca acgcggcaga gttcatgaag ggtgcagacc tcgtcccggt tgcccggatc
    78601 tcgacctcaa aatcgccggt attgccccgt ttcataacca tccgggagca aagggacgac
    78661 gtactgcatc atttaataag cttatgtgta aacatcttac gtagagggga aagtacgtcc
    78721 atcgaaaagg actgtctgac catccggagg aggacttttg acccggaaaa ggcacaggac
    78781 cttggtgttc ccaggggacc cctgttcggc cggctgatga agggggagac cgtgctcgtg
    78841 ggtggaaggg agattactcc ggatatggtc accgcaaaga cagagagacg cattcacatc
    78901 ccgggactgg agaagttcgt atgaggtcta tcgtagaaga ggcgctgacc agggtaagcc
    78961 aggaaatgcc ggatgccagg aagaacaacg aggatctcga ccagatcctc aaggaactca
    79021 ggaccgagat cgccgtcatc gggtgcgggg ggagcggttc gaacacgatc acccgcatga
    79081 aggaggaggg gatccacggg gcaaggctga ttgccatcaa taccgatgca caacacctct
    79141 cccgcacggt tgccgaccag cgtatcctca tcgggaaaca gaagacacgc gggctcgggg
    79201 caggatccat cccccagatc ggggaagagg ctgcactcga aaacgaggag gagatcaaga
    79261 gggctgttgc aggctgcgac atggtcttca tcacggtcgg cctcggggga ggcaccggta
    79321 caggagccgc cccgatcgtc gccaaggctg cgagggacga gggtgcactc accatcgggg
    79381 tcgtcaccct ccccttcacg gcagaaggcg tcatccgcat ggagaacgcg gaagccggcc
    79441 tcgaacgcct ccgtgacgtg gctgatacgg tcatcgtggt ccccaacgac cgcctcctcg
    79501 aggtcgtgcc caagctgccc ctctacgcgg cattcaaagt cgcggacgag gtactcatgc
    79561 gggctgtcaa gggcatcacc gagctgatca ccctgcccgg cctcgtgaac cttgacttcg
    79621 cggacgtccg caccgtcatg gaacggggag gtgtcgccat gatcggggtt ggcgagagcg
    79681 agagcgaaga gaaggcagcg gactctgtca agaaagccat ccggtccccc ctgctcgacg
    79741 tggacatctc gggagcccac gccgcgctcg tcaacgttgt cggcggtccg gacatgacca
    79801 tggaagaggc cgaaggagtg ctccaggagg tctacaaccg catctcgccg gatgcgcgga
    79861 tcatctgggg cgcgcagata gaccccaaca tgcagaacaa gatgcggacg atgctcgtgg
    79921 tgaccggggt acggtcgcca caaatatatg gtaggaatga aaaaattacc cccaaagtcc
    79981 agaagcaatt cgagatcgac tttttgaagt gattgaccat ggagattgcc aagccggatg
    80041 tgaaattcaa tatcaacgag gaactcttcc gcaagtactg gcgtgtcatc aagctcgccc
    80101 ggacgcccac ccgcgaggag ttccaaaaga ttgcactcgt ggcagctgcc ggggtcctca
    80161 tcgtggggct tatcgggttt atcatctatg agctgatgct cctcgtgctt tgattgacat
    80221 ggaagagcag gtcaacagga tttttgcaat caagaccacc tcgaagcagg agaggacggt
    80281 agcagacaac atcaagaagg ccatagagac cggggcgacc gatatcaagg tcgttgcaat
    80341 catcgtcccg gacgaactca aaggctacgt cctcgtcgag acaccggaaa gcctcgcccg
    80401 catcgagcag ctcgcagaga aagtcgccca tgcgcgtact gttgtccgtg gcgagaccac
    80461 gctcccggaa gtggcccact tcctcgttcc caaacctgtc gtgagcggca tctccgaggg
    80521 gacaatcgtg gaacttatcg cgggcccgtt caagggagaa aaagccgttg tcaagcgtat
    80581 cgacaccggg aaggaggaga ttacggtcga gctgtacgag agcgtcctcc cgattcccat
    80641 caccgtcagg ggcgacaacg tcagggtcgt ggacaggggc gagggtactt aaaccaccct
    80701 gccgcacccc gtcccctggt atacctttaa gtccgccgga gtaaaccttt tttacccacg
    80761 cttggtccca tacgggacgg catggtgata cacacatggc agaagtggtc gaggtattag
    80821 ttgctggagg taaggcaacc gcaggtccac ccctgggacc agccctgggg ccactcggca
    80881 tcaacgtgaa ggcagtcgtc gacgagatca acgccaggac cgcaagcttc aacggcatgc
    80941 aggtaccggt cagggtcgag gtcgatgaca agaagaactt cacggtaagc gtgggggtcc
    81001 cccccaccac cgccctcatc aagaaggagg tcaatgtcga gaagggatct ccggaaccca
    81061 acgtcaagat cgtcggggac ctgcctatcg aggccgctgt caggattgcc cgtatgaagc
    81121 agggcgatat gctctcctat gacctgaaat caggggtcaa ggaggttatc gggacctgcg
    81181 tgagtatggg tatcaccgtc gatggaaaga gggctaaaga cgcccagaaa gccgtcgacg
    81241 ctggcaccta cgacaagctc ctcgtggaat agacgagaga gaaaccatag aagatcagtt
    81301 atggtcgcgc actatggagg taacagatgg tggaaagggc aaaaatagta gaggctgtca
    81361 aagcggccat cgaaaaggcg ccttcacgca agtttgctga gagcgtggat atcactgtca
    81421 atctcaagaa cattgacatg gcgcagccca aaaatcgtat tgatgagacg attctcctcc
    81481 cccatggtac cggcaaaaaa gtcggcatcg ctgtcctcgg gaagggtgac atcaccaccc
    81541 gggccaggga agcaggcgcg gacctgatca tcggaccgga agagatagaa cgactcggag
    81601 gggctccccg cgaggcccgg aaaatagcga gtatgtaccg tttcttcatt gccgatacca
    81661 gtgtcatgcc gcaggtaggg cggttccttg gtccgcgtct cggaccgagg ggacgcatgc
    81721 ccatgcctgt gccggccggg accgatatca agccaatcat tgagcgtctc cgcaattcgg
    81781 tgaagatcag gacaaaagac aagaagacct tccacgtcaa ggtgggatcg acgggaatgc
    81841 cgcccgagca gatagcggaa aacattgaca ccgtgctgcg cagggtggaa tccgtcctgg
    81901 aacagggacc catgaacatc aggtcggtgt acgtcaagac gaccatgggg ccgccccaga
    81961 gggtggtata gaatggtcct gtacacgcac catctccccg cgtggaagag gaaggaagtc
    82021 gaagagatca aggccgatgc cgggaagtat accctcgtcg gcctcgtgga catgtacggc
    82081 atccctgcaa gccagctcca gcagatcagg cgtaacctgc ggtcaaaggc aaagatcaag
    82141 atgacccgca acaccctcat ccgctgtgca ttcgacgaag tgggagagcc ggtcgcgctt
    82201 ctgaaaccgc acctgtccgg tcactcggcc ctcatcttca ccaatgagaa ccccttcagg
    82261 ctctacaaga ccctggagaa gacgaagacg aagatggctg caaagccggg tgagacagcc
    82321 cctgccgata tcgttgtgga gaagggcccc acgagtttca agccgggccc catcgtcggt
    82381 gaactgcaac aggcagggat acccgccgca atcgaggccg gaaaggtcaa gataagggag
    82441 acccggaccg ttgtgaaaaa gggagaggtc atcagcgcaa aactcgcgga tgtcctcgcc
    82501 aagctcgata tcaagcccat ggatgtcggg ctgtccctcc aggcagcgct cttcgaggga
    82561 tccgtctacg agccatcagt ccttgcaatt gacgaagacc tgatatacag ccagatgcag
    82621 ctcgctgcag tccaggcctt caacctctcg gtcaacgcag tcatcccgac gaaggagact
    82681 gctgtcccga tcgtggagaa ggcagcccgc gaggcccggt ccctggcaat agaggcaggt
    82741 gtctactcca aggacgtcat tgatgcgata attggtaaag cctaccgaga atccgttgct
    82801 ctcagggggg taaccggaga gcactaaaaa agagaagaga aaagaggtac ttgagatgga
    82861 gtatatctac gcagcccttc tcctgcacaa ggcaggaaag gaagtcaagg aagagaacgt
    82921 gaaggcagtc ctgaacgctg ccggtatcgc cgttgatgat gcacgggtaa aggcaatggt
    82981 cgccgctctc gagggaatca acatcgagga ggcaattgca aaggccgccg ccgcaccggt
    83041 tgcagccgct gcacccgcac ctgctgcagc ggcacctgca gctgccgctg ctgctgcacc
    83101 cgccccaagc aaggaagaga agaaggaaga ggaagagagt ggcatggcag ggctcggtgc
    83161 cctgttcggg taaaaccctt ttttccctcc cgtttcaaac ggacgctttt tttgacattt
    83221 tttccggcgt gatcaccagg ataacacgcc cgggcaggaa ccgatcccct catcgaacca
    83281 cgccgtaaca gaggactgcc ggccgggtcc cctgcaggac ccggtgtttc gtcccggata
    83341 ccaatctcct tatatctgcg ttcctgtaac catctttgtc atggacacgc tccctgccct
    83401 gctcatcgtc ctcgtcgtgg caaaagtcct cggtgaactc gtcgagcggg cagggttccc
    83461 cgcactggta ggcgaaattg ctgcaggagc cctccttggc cccgcactgc tcggcatcgt
    83521 caccatggat gataccatcg gcacgttcgc agatatcggt ctgatcgtgc tcctttttac
    83581 gagtggtctc cagctcaaca tgcgttcttt ccggaattcc gtcaggacgg gattctccgt
    83641 tgccctgtgg ggggtcatca tcccgctgct cgggggaacg gctgccggcc tcgtgctcgg
    83701 gttcggccat gtcgagtccc ttgtcatcgg gataacgctc tcgatcacct cgatcggggt
    83761 ctcgttgcga tccctcatcg acctccacca gttgaaaacc gatgtcggcc tcgcgatcgt
    83821 cagtgcagca gtcatcgacg atgccatcgg aatcgtcctg cttggctccc tttctgctct
    83881 ggccctcaaa gagagccagg tcagtaacct tgcagtcctc ctgctcctcg ctgccctctt
    83941 catcgggctt ctcctcactg ttggcaggag agctctcgtc tgggtcttca aagcctcgca
    84001 aaaggcccat acccacgaga tgtcctattc ggtggcactc gtcctgggac tgctgactgc
    84061 ggtcctgtcg aacggggcag ggctccacta tgccatcggt gcattccttg ccgggctcgt
    84121 cctcggggac agcatccgga gcgaccagac cctctacgac agtctctttg acgttgcatt
    84181 cggcttcttt gtcaccatct tctttgcctc gatcgggctc ctgttcccct ccgatctctc
    84241 ccacttctcc gtattcctgc ttgttgccct ctttctcctc gcccttgcaa caaagacagc
    84301 cgggggactg gccggcgccc ttcctgcctt caaaaattac cggaagtcct tcctagtcgg
    84361 gcttggcctc tgcccgcggg cagaggttgc cctcgtggtc gtcaaagtat ccctggctgc
    84421 cgggctcctg tctgccgcac tcttttccac gctgacgatc gtgatcattg gaacagtcct
    84481 cgtgacacct ctcctcctgg catgggggtt ctcttcccca aaaaaaggtc aggaatcccc
    84541 ttcggatgca aggtaggaaa ggatggagca gacatcaacg atgccgacca gtactccttc
    84601 cctgttgacg acgacgagat ccgggtggtg gtgtttctcc atcagccgca gggcctcgga
    84661 gagaggggta tcctgcataa cggcgatgtg accccgtgac atgatgtctt ctgcacacag
    84721 gtcatcccgc gagaggagtg gcccgaggtg gtgcgatttc ttccggctcc gcactcccat
    84781 tcccggaccg aggtgtgcca cgacgtcaaa cggcgtgatg acaccgagga agtgcccctc
    84841 ctcatcagtc acgtagaggt cactgcaccg gtctccaacg atatggcgga tgcaggtatc
    84901 aaggggtgtc cgcggcccga ctttgatgaa ggtcccgctg accaggtccg agaggggagt
    84961 cgtatccggg gatgatccct tcccgttcct gcccccgccc tgtgacctgc ccccgcnnnn
    85021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    85081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnctca tgtacctgtt ccccctctcc
    85141 ggtttccgga aagcacgtga gggagtatgt gttccggatg actaaaaagt gtggatgacc
    85201 cgctccggat ccggtcatat tcacagcaca gagcggacct gttccctgca cacgggacac
    85261 aaccacctct tctggcgcgt gagatcctcg agcgtgaggg ggttatacat gatgcattcc
    85321 ctgcacctgc agtgtgcgag ggagaggaga tgtcccacct cgtgggctgc ctccttgacg
    85381 agccggtcga agagttcctc ctcgtcgggg gggaggccgt agtgggcatt ggcgaggcgc
    85441 gatgtcgaga caacggcgtt tcccgtctcg ggccgggcga ggccgaagag gtactcgtcg
    85501 ccatcgcggc acaggtcctc ggaaacgacc aggaggatgg ggtcgcagac ccccgaccgc
    85561 ctcttgtaga tatccagtga gtcgaggagg acagatgcat ccgtctggcg tcgttccggg
    85621 cggtatcccg tcaccaggag gggattttcg cacaaccgcg ggacaaccgg caggagtgcc
    85681 gccagttccc tgcagaatga tgcctgaata ccggccgggg caccagaatc ccaaaaaata
    85741 aggagttcca ttcctcacta ttcatggtaa tggccgggct taaacgtatt gagagactga
    85801 ttgcatccta cattgcagaa aattaccgca gcgccgctga ggtgggagcc gggaagaacc
    85861 tcgaggtggc ccggctgctg caggagcggg gtgtatcggt cttctgcacg gacatcgcac
    85921 cgcccccgcc ggacccgggc gtcccgttca tccgtgacga cattttttca ccgcaggccg
    85981 ggctctacag gggctgcgac ctcatttatt ctgtacggcc ccacgaggag atggtgcccg
    86041 ccctcgtccg tctcgcccgg accgttgact gcgacctcct cgtctatcac ctcggtttcg
    86101 agggttacgg gaacggtggt gagatcatcg actgcggtgt cgtcctgcac aggtaccaca
    86161 ggtgtcagaa tccatcaaaa agtgtcttct gattctttgg gggggacctt gcaggggcac
    86221 cgccctgctc cgggaggacc ggttccggag ccggggcggg cacgaaggaa ggttcctcct
    86281 cgtctttctt ccgggaccgg gctgctttct ccttcttttc cttctccctc ctgacctcct
    86341 tttccttctc ttcggctgca agtgttttga tgacggaggc agcacgtgaa cggtcatgga
    86401 tggcaagggc aagctcgtcg gcatcgagcc cgaactccct tgctgccgtc aggggatcgt
    86461 ggtctatgag aaggcagaga ggatccatgt attcctcgag cagggtccgt tccggcatgt
    86521 ggagacctga cgcgagcttg cggagaaagg acgccctgac ggttttctgc ttctggtacg
    86581 aggatatcct cttccaccgt tcggggggca tgatgcgcga atggataccc ttccctgccg
    86641 tgacacgggc gacaccgagg agcatgaggg catgtgcgta ccgccataac gtgtaatact
    86701 ggaggcggta cgtatcgccg atgtacgtgt cggcccgcag gagagcagaa tatgcagtat
    86761 cgagatcctg tatccggtcc attccggcga cgtttgcctc gatccactgg atgagtgtgt
    86821 cgggtggctc atcggcatcg taggcgagcc tgaggaggga ctcgggatcg gtcctcccgt
    86881 acagggcacc gataacatca aagattgtcg atcgcgtatc cttcgcagaa atggaaatgt
    86941 cctcgtcgag ccggtccctg cccgcggcag cagcctggag catgtggatt gcagccctca
    87001 tgtcgccacc tgcggattcc gcgatctttt tgagcgcgtt ctcgctgcag gcaatctttt
    87061 ccgcgctgca gatgaaccgg aggcggggga cgatcgaccg tgcctggatc gcccggaact
    87121 ggagggcctc gcaacggttc cggatctccc cgggaactgc atagaggtcg tttgcaatga
    87181 ggatcaccgg ttggcgggcg acgcggagga gttcgagaat tgcacgggcg cctccccgat
    87241 ccgcggtccc gtgcaggtta tccgcctcgt cgatgatgac gagccgcctt ttccccgaaa
    87301 aacttgcagt cgtgctcccg ctcccggcca ctttctcgat cacggccctc gtccgctggt
    87361 cgctcgcgtt cagctcgatg gcttcccacc ccatgtcgga cgcgagggca tgggcactcg
    87421 tcgtcttacc tgtccccggt ttgccataga ggatcagggg ttttttcccg gcgtcccagc
    87481 cccgcgccca atcgagcatc tggtggagaa tggcggtatt tccaacgatt tcatcaaggt
    87541 gagcgggcct gtatttttcc gcccagtcca tgtccagaca ttcgacccgt aatcaaataa
    87601 attatcactg atgatgctcc aatgagttat tacaaccgcc gttgttggtc ctatggaatt
    87661 gaacggtgta tccacagcag agattgctct ttctgtcagg gagtacgagg gagtccggcg
    87721 gaaacaggcc atcggcgaga tggtcagggc attgcggatt gattctcccg gcatccttgc
    87781 gtcttttggc gaagatgccg ccgtgatcga gcatggcgac gaagtcctgc tccttgctgc
    87841 cgacgggata tggagccggc tcatggaggc cgacccctac tgggcaggat actgcgcagt
    87901 cctcgtcaat atccacgata ttgcggcaat gggggggcgc cccctcgcga tggtggatgt
    87961 tttttccata tcggatacca ccatccagaa caaggtcatt gccggaatgc acgacgcatc
    88021 actccagttc ggggtcccga tcgtgggcgg ccacctgcac ccggatacac cgtacagcgt
    88081 catcgacgtc gcaatcctcg gtatagcgca aaaggatgca gtcatctatt cccatactgc
    88141 ccgtaccggc gattccgtga tagtggccgt tgacctggat ggaagggtgc acccctcgtg
    88201 cagtctcaac tgggactcgg tcaccatgaa gagccccggg ctggtacggg cccaggtcag
    88261 ggtcatggag gggcttgcac gcgaccacct tgtcactgca ggaaaggaca tcagcaatcc
    88321 cggcgtcatc ggcacactcg gaatgctgct cgaggtgagc ggcaggggtg cgacgatcgc
    88381 gctcgagcgg ctcccaaccc cggacctgcg caggcacggc atgacgtttg agcagtgggt
    88441 cagggtctac ccgggaatgg gattcgtcct gactgctccc cggggttcgg tcagcgagat
    88501 ctgccgcagg ttttccgaag tgggcatgac cgcggcagag gtcggcgctg tcaccgatga
    88561 aaggacactc tccatctccc tcgataatga gaagaccccg gtcttttcgc tcgaccggac
    88621 cggggtcatg cgcctcttct ccggtgggga accatgccgg taagacggat cgggatcggt
    88681 gttgccgctg atggtgcgag ggtgcaggag agtgccagga aggccggcat cgattcacgc
    88741 gtcatttttt atgcaaagcc gggactgctt gatgcggggc aggatttcgg gatcgaggag
    88801 ggtgacgaac cctggaagat gctcgttggg gacctttatg caggaaagat agatgctgct
    88861 gtcaggggga ctcttccgtc aggtgccact ctccgggtgt tgcgggaagc cgcaggcgtc
    88921 gaccacctcg aacgtgcagc actcctcgaa gatggaaaag gccggagatt cctgcttgct
    88981 cctgtcggga tcgacgaggg ctggaccgtt gttgacaggg tggcgattgc acggagaaca
    89041 aaagatctgg ctgggattct cggtctcgag gggggagtcg ccatcctctc gggcgggagg
    89101 ctttccgatg cgggaaggca cccgcgggtc gacgagagcc ttgcccaggc cgagctcgtc
    89161 gcacgactga caggttttcc ccacttcgag atcctcatcg aggacgcggc agaggaatgc
    89221 tccgttatca ttgctcccga tggaatctcc ggcaacctcg tcttccggac ccttgcgctc
    89281 ctcggatgcg ggcagggaca cggcgcacct gtcctcaata ttgaccgtat tttcatcgat
    89341 acttcgcgcg cttcgcccag ttatgcaaat gcaatccggc ttgcggaatt tctcgtgagg
    89401 agcgcaaaaa cgcgatttta actgctattt tttccaaaaa atggttatta ttgcgattag
    89461 agagtattca caaccgtccg gagagcattt tttcgtaatt acccgtgaga acttcgcaaa
    89521 ccgacaacag cgctcgaata ggtcaaaatt cacgaaatct ttaaatattt cctgatacat
    89581 tttttgaatt gaggtaaaat aaatggcaga tttacctatt gctgcagttg tgagaattgc
    89641 caagaagaat ggtgctgaga gggtcgggag cgatgctgcc gcagccctcg ttgcaaaagc
    89701 tgaagagtat attgcaaacc tgacaaagga ggcaaaccgc ctcgccctcc acgcagggag
    89761 aaagaccatc aaggaagagg acgtggaact tgcggctaag tccgcataaa cctcaccttt
    89821 tccccgttct cacacggaga taaaagagca gcaatcagac aatcaaggtg gcatcacact
    89881 tttctcgcgg accccgccca cgggagagtc ttctcctgtc gcgacagatc gagtataaaa
    89941 atatatgcct tgcattactg gatgacacag ggatttatcc tgccggtaaa gactatgatt
    90001 tgcccttacc ggggctggcg ggggttataa atggccatcc atacacaggg agtggcggaa
    90061 gagaccaggt gcgacatcat ccattcgatc tacgatctgg ggaagaaagg tcagccggca
    90121 gttgactttc tcctgctggc acttaaggat gaggacaagc gggtaaaaat cgctgctgca
    90181 aacgccctgt gcgacattgg ggatgccagg tgcgttgatg cactcattgc cctcctttcg
    90241 gacggggaca aggacatccg gttcgtctct gcatcgctcc tcgggaagat tggcgacccg
    90301 cgggcacggg aacccttaac ccgggcctgt gccgatgaaa actgctttgt ccggatcatg
    90361 gcaaaggaag cgctccaccg aatccggtaa acccgtccct gcacgaatac ccgcaaccaa
    90421 cgaagggcat aacctttttt accaggagga gtactcccac agtgtggggg gattcccgga
    90481 tggcgtcaac aggaaagatc aatgtaacct atcccaccgt cgtggaccgt gcttaccagg
    90541 aatacaagag acaccggaaa gtgtccgata tcatgagttc cggggtcgtg atcaccacgc
    90601 cccagacatc catgatcgaa gcagcacgga taatggggga acgtcgcata ggaagcctcg
    90661 tcgttgtccg ttacgggact ccggtcgcaa tcgtcacgga aagagacctc ctctccaagg
    90721 tctttgccgc cgaccttgac cctgctgacg tgtctgttga agatgtcatg tcatttcccc
    90781 ttatccgcgt ctgtcccgac atcgagattc gggaggctgc ccgcacaatg atccggaaga
    90841 aaggccggct gaccgttttt gcgtgcgggg agttgtgtgg aatcatcacg gcatccgacc
    90901 tcatccgcga gatgccggat gcaagggaga cctcgatgac ggtcaacgat ttcatgacga
    90961 aggatgtcgt gtacgtcggc gaagacgaga agatatccga tgtggtccgg ataatgggga
    91021 cggagaggat aggaagcgtg atcgtcacga cagggggaaa tccttccggc atcttcacgg
    91081 aaagggatct cctctcgact ctcatggccc gtggcgcagc actcgatgtg cccgtcggag
    91141 aggtcgcccg ttcacccctc atctcggcac cggcgggaat cagcatccac aaggccgcac
    91201 ggatcatggc cgagaaccat atcaggagac tcctcatcat caagagaaag aggattgcag
    91261 ggatcattac cgcaagggac ctcgtcgagg catacgccct gtaaaggggg ggcagaagga
    91321 aagccgcatc ccgggggcac atgatacggc ttttccaaac gggagcatct cccggcaata
    91381 ccccttgccc gccacgcacg tgagatctga ccatgcagga cgaaaacgga cttgaacagg
    91441 caacgtttgc cgccggttgc ttctggggtg tcgaagccgc attccggcgc gtgaagggag
    91501 tggttgagac ctgggtgggc tataccgggg gcaatgttcc ggaaccgacg tacgaagaag
    91561 tctgttccgg ctcgaccggc catgcagaag ccgtcaggat cattttcgac ccgcgtatcg
    91621 tctcgtatga tcagctcctc ggggtattct gggacattca tgaccctacc caggtcaaca
    91681 ggcaggggcc cgacatcggg acgaactacc gctctgccat cttctaccac aacgatgacc
    91741 agaaacggaa ggcactggca tcgcgggacc gggtccaaca atccccccgg atgaaaggaa
    91801 aaaagatcgc aaccgaaatc gtccctgccg gcccgttctg gaaggcggag gattaccacc
    91861 agcagttcta cgaaaagagc gggtggggat atgcagcacg cccgaagtac tgggagtagc
    91921 aggctcccgg ggcaggcggg gggacctgta ttcagggggg cggatccctc ttcatggggc
    91981 agacgtttgc tccctcgagc tccccgcctg caaaggcaaa ccgttccctg atcgtcggtg
    92041 gcagttcggc ctccgggatc tcccggaacc cgaatttctg ataaaaaccg gtgaggttga
    92101 ggaccgagtg catatagagc gtgtcatgcc cgcatgcctc aacgagggct cccaccgcaa
    92161 ggttcgcata accccggccc ctgtgctcca cgggagtgaa gacagcgtcg acctcgagcc
    92221 cgtcggggtg cctccggcac cgtgcgactg aaacggccct tccgcccgca aaagctgcaa
    92281 agatcctgtc ggtgaccggg tctcccttcg tctggtggta atcgagccag atcctgtttg
    92341 caagggggaa ctctgcggag agcaactccc ttgccgccgg atccggcaaa ggggcagctt
    92401 gcgtttccgc ggggaggggg aagggaggtg ctccgtcacc cgtgccctct atgcggtaat
    92461 tctcctccgg gacatggatc acgaaacggg ctccctttcc ttcctgcccg gtctctgcga
    92521 tcgtcatgcc cgttacggca gttatctggc ggcagatgaa gaggccaagc ccggcgtgct
    92581 tccccgagtc atactcaaag attgcctcct ttttgtcagc cgggatcccc ttcccgtcat
    92641 cctcgacgaa gagttcgagc ccgccaggca ctatgcggta ggagataacg acgtttcttg
    92701 tcttctctcc gtgacgcacc gcgttttcca ccaggtgcag gaggacgtcc cggaagaggg
    92761 gatccgcaaa gatttcaagg cgttccgccc agggtcggat cgaaacgtcc cgggatccct
    92821 ccggaggacg ggcagaccgg aagacctcct ggaccctgat ccactccggg gggaatgccc
    92881 cgaggttctg gtatgcctct gcaagctgga tgtgccggaa aagagtggct gccttttcca
    92941 ggatcccttg aacgagaggc ttgatggaaa cgtccctgca ctggtccgag agcgtgcgtg
    93001 ccaggcctgc cagttcggat accgtcctgt gcaggtgatc cgaggagatc cgggagagga
    93061 ggtgcagctt cttgtttgct gtctgggcgg cttcttccgc tatcacgcgc ctcgtgatat
    93121 ccacgaagga gagtgccgcc ctgccttccg gcaggagaac tgccgacacg atggcatggc
    93181 gggtctctcc cccgggaagg gagagtgcca gttcctgtcc atacactctc ccctcccttt
    93241 ccagtcgcag catgaggtca gcagctgcct gcctgccgat gaaggtcagg agcggttttc
    93301 ccgcaagaga tcccggcgga gccccaaaaa ggcgtgatgc gttccagttc gtctcccgga
    93361 tgaccgcctc acccgtgatc cctgcaacga tgacctggcc tgcctcggag ttgtcaaaga
    93421 tccccctgta gagttcttcc ctctcgcgca accgggacga gaggtgggcg atgagccagc
    93481 cgatgatgac gaggacggca acgcggacgg ctgcctctgc cactatttca ctggttccga
    93541 agaacgagac caccatggca acgtatgcaa ggccgatccc gagtgcaagg aacggcccga
    93601 aacggggata cctgtacgaa ccgatgacga cggggatata gagcaggtgg gggagcacga
    93661 cggtgatgcc catcaggaga ccgatgccgt tgaagacgag tacggcggcc gtcgagacga
    93721 cgagggcgct gttccaggcc ccatccctgc ccaaaaacat attcttcagg tgcatgaccc
    93781 gatacctccg cctgccactc tccggtaccc gggagacagt cttttggaat ctttcttagt
    93841 actccctgtt tcgcaccgcg gcaggccttc ctccggggga gtgcagaata atactttcag
    93901 ggagggatta ttagtggtta ccattccttt cccgggacga ggtggccttt ccggacgggc
    93961 cgatcggaca gtgtctccat cctttcgatg gtatcgaggt caagggagat gatgcggtcc
    94021 agcgataccg gcgtgtaccc cgtgcactca cacgagacgt ttatggtacg cctgatcccg
    94081 ttgatgaacg ggtgaatgtc catcctgttg ttgtgcgtgt gaccatggat aacccagccc
    94141 ttccacgagt ccggaacgtc acacggatca tgcacgaggt aaaacgtgta gccgccgtac
    94201 gagatgacgg aatggtgccg ggctctcagg agagcgttgt cgtggtttcc gcggatgaac
    94261 acctttctgc cccggagtgc ccgtatccag gggactggat ttccccgcat gcagaaatct
    94321 ccaaggcagt agacagtatc ccccgctccg accacggagt tccagcggga aacgaggtca
    94381 cggttcatct cggaaactga cctgtaaggc ctgttgcagt agccgatgat ccgggcatgg
    94441 ttgatgtgga ggtcagagac gaggaatatc cgtccacggc ttttcctgcg caggccaaaa
    94501 aatgcaagga gggaagatcc tgcctttttc agggtttcga acagggaaga tcacctccgg
    94561 ccggaaggga tacactcacc cccgcatctg cgggccggat gggacgggaa aagggtccgg
    94621 cgtgccgttc atttctgctg ttcagaaagg agggtgccgg caatggcaat attctccttc
    94681 tccagctcgt ggatgaggat ggtgacacgc tcgggcggga cggcgaggat acgggatacg
    94741 gtcccggcga tctcttctgc catccgtttc ttctgttcat aactgcggcc cctggccatt
    94801 gtgacggtga cgacaggcat acccgaaaca ttgggagccg gtctccaaaa aaccgtccgg
    94861 tccctgcata ccctgacccc catccacccc tgttccggct cccgccggaa tacccccttc
    94921 cctgtggatt cacccccctc acaggtcgcg ggcacaccct gaatcgattg cagcctggcg
    94981 gaccgccgct gccatcgcac gcgtcacgtc ccggtcgagg gctgtgggga ggatgtggtc
    95041 cctgtggggt ttttccacgt aatcggcgag tgcgtgggct gccgcaacct tcatttcgtc
    95101 ggatatccgc gttgcatatg cgtcgagggc accgcggaag acacccggga acgcaagggc
    95161 gttgtttatc tggttcggga aatcactcct cccggtaccc acgacggcag ctcccgccct
    95221 ttttgcctcc ccgggcatga tctccgggac agggtttgcc atggcaaaga cgatcgggtt
    95281 atcgttcatc ttccgcacca tctcttcggt cacgatgccg ggagcagaaa caccgatgaa
    95341 gacatccgca ccttccatcg catccgcaag cgtgcctgcc ctgcccgaac ggtttgtctc
    95401 gtcggcgatg atgaacttgt acttgttcct gtagagaccc tccctcgccc tgtggatgat
    95461 tccctgccgg tcacagacga cgatgtcctt tacggatcgg cagacgtccg ggctgtaccc
    95521 gatgcagcgc aggagcctcg ttatcgcgta ccctgcagcc cccgcaccgc agatgacgat
    95581 ccggaggtct tcgaactgtt tccctgtcgc cctgcaggca ttcaggaggg ctgcgaggac
    95641 aacgattgca gtcccgtgct ggtcatcgtg catcacgggg atgccgatgt cctggagtgc
    95701 atcctcgacc tcgaaacacc ggggagccgc gatgtcctcc aggtttatcc ccccgaagca
    95761 tggtgcgatg ttcctgacct ggtcgacaaa atcggtctgg tacctctcga agcagatggg
    95821 gaacgcatcg atccctgcaa acttcttgaa gaggatggct tttccctcca tcacgggaat
    95881 ggcggcgtac ccgccgatgt tgcccaggcc gaggacggca gacccgtctg tcacgatcgc
    95941 gaccgagttc cccttgaggg tgtatttgta ggcaaggtcc cggttcttct ggatcgcccg
    96001 gcagacctcg gcaaccccgg gagtgtaggc ccgggagagg tcgcggcggg tctccagcgg
    96061 aaccttggat cgtatctcga gcttgccccg gtgctccgcg tggagtgcca gtgcctccct
    96121 gtatatctct tcccgctcgg gctccatgat cgctcgtgga cgcaaaggct cataaaaccg
    96181 tcctccccgg taccacctct catccacggc catgtcccgc acaaatctaa tacacgggaa
    96241 aaaccaaccg ggacaggtat gccggatcgg gctgtccttt ccctcctctt cgtgggaata
    96301 ctcgctgcct gtgcggggtg cacgctcacg tttggtgacc tgcacccggg cgggaacgga
    96361 tccgcaaatg gctgcgggtt caccacgcac gctctcgtga cgcgcgttat cgacggggac
    96421 acgttttccg tccgttaccc cgacgggagc gacgataccg tccgcatcct cgggatcgat
    96481 accccggaga ctgacgacgc ggggaactca aaagacgttt ttccggggat tccggatccc
    96541 tccttcctca cctcgtgggg aaagagggct tcctcctttt cgcgtgacct cctgctcggg
    96601 gaggacgtga ttctttccgg ggactgcagg gccggcacac gggaccggta cgggaggctc
    96661 cttgcatacg tcacatccaa aggcacggat gccggttccc tgctccttag ggaagggtat
    96721 gcccgtgtct acaccggcga ggacttctcc agaaaggagg agtacctggc actccagcag
    96781 gatgcatggg agaggggtgt tggtctctgg aacccggcgc gggtaccggg agaggccggc
    96841 aacggtccgg tgcggatcgc gtacgtgcag tacgatgcac ccggtgacga cagggagaac
    96901 ctcaacgggg aatacgtctc tctcgtggca gaagaaagga ctgaccttgc aggctggact
    96961 ctctgtgagg gagacggggc actgtatcgc tttccatccc tcacgctcga agccggtgac
    97021 tctcttgtta tccacacggg gtccggggtg ccggggggag gcgaccttta ctggaaccag
    97081 acaatccccc tccttggcaa cagtgcagat tcggtcgttc tgaaagatcc ggccggaaag
    97141 agtgtctcgt cgtacacgtg gggttaggga ctcttcaccg cgtcgccggc aacggcgacg
    97201 gttcctgccg ggactgcccc ccgtgcaccg cgaggcaggc ctggtccacc gcgaagatga
    97261 cctcctccca tgccttttcg aggagacccc ggtagtaacc cgcgtcgaaa cgggcggctt
    97321 tccagtccag atccactgac cacgtccggg catcggtaac tacgaaccgc acctccatcc
    97381 cgggaaagag gtcgataccc tccgccctgc atgcctccac ggccgatgcc tcggcacagg
    97441 catggcggta ggagagggta ctgatcctcc gggtgactgc cattccggcg ggatctgcag
    97501 cggggagggc atcccgggcc tccctgtaga gtgcctggag cgggtcgcgc aggcctgcaa
    97561 cagcgggcag cgttgctgcc gacccgagga cgtgtagcat ccggtgctgg acgtccctga
    97621 tgtacggggg cgtatcaccc ctccgcgccg caacccccct gaccttcatg cttccgtcct
    97681 gcaacctgcc gtagtagcgg ttgtaggcgc cggtcccgtc cgccatgggg agaaagacga
    97741 tccagtcgta ggtacccgca acggcgtgga gcccggtctc gcgctcgacg cgttccctga
    97801 gtgcacggat gtctcctccc ttcacccaca ggcagtccac gatcccgtgg aggacggaaa
    97861 aacccatctc cccggcgatg tcgcgtgtcc ggatgaggac ttcccgggcg cttccggtga
    97921 tcgcctcgtg cacctctatc tgcccgaact tggcgttgcg gtagcccgtg tacccaaagc
    97981 acgtgacgag catccacttg aggagggcgt cgcggcctgc gtaccggggg tcggatgcct
    98041 tcagctcctt tgtcctgcgt cgcatggtaa gcaggggttc gaggacatcc gggagaaaac
    98101 ccctcctccc ggggcaggtg agcgtctcgg gagagaggtt gtcccggacg atgagggagg
    98161 ggtacagcga ggtgaaatcg atctcgaaga cacggtcatg gataccgggc gcgggctgga
    98221 agatcatccc cccgcggtcc gcggcacgga ggtcgggaag gcgccgcacg ctctcggcgt
    98281 ctgccttcct ccaggggacc gcaatgcccc tcctctttgc ctcgtacacc tcgtaggaag
    98341 agatgagtgt cccggaagag aaacgcgata cgaggtttgg ggggagacac gagagccgcg
    98401 acccgagaag gatgcccaaa agcccgctct ccctgtagtg gaagctcccg gttgtgtcga
    98461 tcagcagcct cccgtcgggg atgagggctc ccgcacggaa ctccgtcctc ccgtagctcc
    98521 agtacgactt ttgggagagc cggcggaacc tgcccgaccg cgagagtccc gtcccggtgc
    98581 ctaacccgcg tgcccgtgcg accatccggg gaacccagag gtcggcatgg ggaaagagga
    98641 tgacgtcagg gtctgcagag gagaggaccc cctcgaggtc cgcgaggatt gtcttctcgt
    98701 ccccctccag cctctccctc ctcccgtctg cgacgagcac gagggcaggg aggggaccgc
    98761 tgacgaaggg gtttcccgcg ggcaggattt ccacgacgga gaggtcaggg gagaagtcaa
    98821 cagagaaacg ggactcgccg tcttcgctgc aggggaaaaa ccccccttct gccatgagac
    98881 cgaggtcggg gcggatatcg gcatcgtaga tctgcgcctc gtatcgcgtc tgttcctcga
    98941 tccgagctgc aacgtctttc cctgcccaga cccggtaacc atcgagaacg ccgtggatcg
    99001 tccggatggc acactcttcc actctgtagc ggctctccag gccctccacg aggtcacggt
    99061 gatagtgagg gtcggggagg tggaggagga aggagggggg tgcaggccgg gtaacgtgcc
    99121 gccctcccct ccccttctcc cagaactcca cacggccccc gcgggcacac gagtcaagga
    99181 tccacacggc ccgctccctc cccgcattcc cctgccagct ccaggagaac cgagaagagc
    99241 gcggcctcca gggggtcgtc gaacgcataa aaacactcgc tcgcgtgtgc gcctgccatc
    99301 ctggccacgc gcagggcaac ttcccggtca cgacccggga gagtgcgtgc agccctctcc
    99361 caccgctccg tgagggccct gacctcctgc ctgacactcg tgaaactccg ccccatctca
    99421 cacgccctcc agcgtctgct gcccccgcgg gagcttcccc gggaaacgga tctttccgcg
    99481 tccccgcgca cggggtgccg gcagacctgc cgcggggctt gcaaggtaaa agacgcggtc
    99541 ggcaagccct gcaatggcct cgaaggaggg atcgggaaac gcggtgtaca ggacgacgag
    99601 cgcgccctgg ccgagctgcc ggagatcctc tcccacctgg tgtgccacgc ccccggcccc
    99661 gtcgtacagg gtggggtcat gctccacgaa gacgatcgtg tggtacgatt cacgcaggat
    99721 ctgcaggagc tggaacgccg tgaatgcccg cctcacctcg atgctgaccg tcctcctgtt
    99781 gatccccgaa agtagccgcg aatagttccc gctcacgaag aggaagagga agcgcgagag
    99841 gacggggttg tcgttcaggc ctgcaaggac cacgtcctcg ggcgcgacca cggcagagaa
    99901 cgtcccgctc cgcagtgtca ccgagggacc aagcaccagc tccatgcctg ctacactggc
    99961 acgccccatg ccataagggt ggagagagcg cggggtgaaa gtgctcccgg tgggttcaaa
   100021 taggaggaag atatccgatt attgaaaaga ttctgataat tgcgttccta tatcccaaga
   100081 aatggctgtt gctcccctgc atgatctgca ccatctcctc cctctcctcc ccggaaatca
   100141 gggtgaactt cttcgcggac aatgagtgtc aggatcacga tgatcagccc gagcaaaaaa
   100201 gacccaaaga acgcaaggtc gaacccggct gcaagcacag ggagggtgag ggttgccggt
   100261 gcggacgcgg tgacaccccg gtgccgtgca atggaggtga ctccctggat gaagacgagg
   100321 ttgaagatgg cgatgcccag cgtgatgggt acgtagcgct cgaggctggt gaggctcgaa
   100381 accatgccct ggtaactccg cgggacggca ttcatgatca tgttcgtgag gggcgtgatc
   100441 aggaggccca tcccgagccc gatggtgatc aggcatgcta cgatagacat ggtcgtcgta
   100501 tcgactttca ggtgccacat catgaaatac ccggcaagca ggatgaccgc cgcaccaatg
   100561 gaaaggggtc gcgggccggc acggttgtag aggaaacctg acacaatgcc gccgaccatc
   100621 atgcctgccg aaaaggcggt caggattagc ccggatacgg atggcgggaa ccccttgaca
   100681 tactcgagga aaaaggggag aagatagctg atcccggcaa aactgagaaa aaccagggcg
   100741 aggatgaggt tgctcaggga gaaattgcgg ctcaaaaaga ggcgtaaatc gagaatgggg
   100801 tcatcggttg agacctctct ccggacaaag aaaagaaggg ctgccccgga gagtgcaaca
   100861 gatgccacga tgaccggaga tgtccatccc agtgccggcg cctccgtaac agaaaagatg
   100921 agggctgcaa ggccacagaa aacaaggatc gcgccctgca catcgaaccg tttcgtcccg
   100981 gcaggccttt ccaccggcgg gatgacccgt gcaccgagca ggactgctcc cataccgatg
   101041 ggcacgttta tgagaaagat ccagttccat gacaggtact ggatcagcac cccgccgaca
   101101 gccggaccca gtgccgtccc gagtgcggca agtgtcatga ccgtccccat tgccgcaccc
   101161 ctcctctctc ccgggacgta gacagagacc attgcaggtg caattgccgt catcatggcc
   101221 ccgccgatgg cctgaaagac cctggaagcc acgaggagtg ggaaagagtg gaaaaggtcc
   101281 ggaagcatcc cgcagaagaa cgaaccggcg gaaaagattg caaaacctga aaggaaaacc
   101341 gatcggagac cgacaacgtc tgagatcctg ccaaagacga ggatgcaccc tgccaggacg
   101401 agcatgtagg ccgtggcaac ccagctgaca gtgctcgatg atataccgaa tgcttccgaa
   101461 attgtgggaa gggcaatatt gacaatcgtg ccgtcaagcg acgacatgaa gatcgcaagc
   101521 gatatggaga agacgaggag gccaaaagac gtttcctgcg gggacgatgc gtccttcata
   101581 ccccttacta tcatctgcac ccggggttat tccttccgga ttgcgcgaaa ccatgcagcc
   101641 ggcccgtttc ccccgggacg ggggataaaa ggaaacagga atgcggggaa ttatcatccg
   101701 gattattttg gattgaaaaa gattaattta aaaattttta tataatctct ccgtttacca
   101761 ctagtagtat cgcacaggtg tcatttattc atgatccggc tgctccatgt cgatgacgac
   101821 agtgtaatcc tcgaacttgc cggtcttttc ctgtcacagg caggtgactt ttccgttgac
   101881 accgccacat ccggggaatc ggcaatcggg atgctctccc ggcaggagta cgatgcaatc
   101941 gtctccgact acactatgcc ggggtgcagc gggctggacc ttttgaaata tgtccgggaa
   102001 aaggacaaga atacaccttt cctcattttt tccgattata atgacgagga ggttgtgatt
   102061 gatgcactga cctccggcgc tgactttttc ctcccgaagg gactccacgt gaggtcacag
   102121 ttcatccagc ttgagcatgc catacgcgag tctgtgatgc gccgtcgcgc agaaaaacag
   102181 cacgacgacg tctctgcgcg tttaaaggtc atggaggctg caatccgcgg atccccccat
   102241 cccctctgct tctgcgatat ctatggcagg atccggtttg ctaacagggc aagtatagag
   102301 ttatgggggt attccgatga tacagaaatc atagggaaac atgcgattga gttcgtcgtc
   102361 tcgccggaga tcgacacccg ggcaatcccc gatcttctca cgatgaaggg ctggtcgggc
   102421 caggctgtcg cgctccggaa agacagatca acgttcgatg cacaggtcca tgtcaacgtc
   102481 atccacgacg attcgggtat tcccctcggt ttcatcgctt cctttacaga catcaccctg
   102541 cagaaagaga cccggtcccg gctcgaggcc tacatcaggg ccatgcgttt tgtctcggaa
   102601 aaggcaagtg aactggctga attcccactc gatggagaca tttattcttt cattgccgac
   102661 tcgttggcac gccttgcgcc ggaaggatcg gcagtcctcg taagttccgt gcagcccggc
   102721 cccgtgctcc gcctcgaatc agtcagggcg gacagggaga ttatcgcaga agcgacacgg
   102781 attatcggga gacccctgga ggggcttgaa tttgacctcc ccgccgaaaa acaggatctg
   102841 tcctttcctc ctgtattcgt cgatatcgcc gggggaataa aagaactctc gtttggccgg
   102901 ataccggatg aaacctgcaa aaaactcgaa gaaaccggct ctttcgggag gatcacaggt
   102961 tccggcctcg tatggggggg aaagacccat gctgttaccg ttcttctgct tccccgggga
   103021 tcccaccttg aaaataccga tgtcctcaac ctcttcaccc tccactgctc cgccgtcctc
   103081 cagcggagag aggcagaacg catgctccgg aacctgcgga cgggatagac tctttccgga
   103141 ctcgcgggaa ctttttcagt aattttttat acatgaatgt ataaaattat acatcattga
   103201 ataaataagg tgataaccct tggattgtta ttttggccag tccgcttcct cccgcacgaa
   103261 gatccagttc ctctatcctt ttcccggaca gggattcccc ccgggcattt ttgccgggtc
   103321 ccgcccctgg tggacgggca gttcccccgg ttctgtatag attccagaag acgtttacaa
   103381 tgaagagaag tgagtttcca tgaaatcaag agacattgca attgttggta tattgctggc
   103441 cataggtgcc atcctgcgct acttcctggc catgctgcac acgccgctga ccccgaacat
   103501 gatcatcgca ttctactgcc tcgcgatcat cctcgtccgg cccagggtac acgaggcact
   103561 cgggatagga atcgttgcag gaatcctctc catgctcatc tcgagctcga tattccctcc
   103621 ggcgaacctg atttccgagc ctgtcggtgc gctggtctgc ttcgggctgt atgccatcct
   103681 gaaggagaag acagggacac ccgcagtcac gacattcgtg accacgctcg caagcggatt
   103741 ttcctttgcg gcagttgcac tcctcgcggt cgccccgaag atactggaca agtactcgac
   103801 cgtctttggg tttgtcgttg tcttcgtccc catcgtggtt attaccgcgt ttttcaatgc
   103861 aatcatcgtc cagatcctct actatcctgc cacccgggtt ctttcaaggg gatagcccat
   103921 gattacgctc gaggatgtca gctacaggta ccagaggggc gggagggatg cagtctccgg
   103981 catctcgctt tccgtttcac ccggcgaatg cctcatgatc acggggccat cgggagccgg
   104041 gaagacgacc ctgtgcatgg cagcatcagg catcctcgag catgaatttg ggggtgagaa
   104101 gagagggcgg gtcacgatac tcggcaaaga tgtcagggaa tacccgggtt tacccgagat
   104161 tgcatcccac gtcagcgtgg tctttgacga tcccgaggca cagctcatct ttaccaccgt
   104221 cgaggaagag atcctctctg cactcgaaag aagcggacta tcgcctgccg aaatcgggca
   104281 gagacttgca tcaatcctcg agattacccg gcttgcagcc ctgaaagacc gcccgcccca
   104341 cgccctctcc ggcggtcaga aacagagggt tgcgctcgcg gccgcccttg ccctcgggac
   104401 ggatatcctc atcctcgacg agccgacagc cgagctcgac gaggagggga ctgcaagcat
   104461 cgtctcggtc ctccgggatc tcaaggcgca gggaaagacg atactcctca cggagcacaa
   104521 gtattcccac ttcagggatc tcgtggaccg cctcgtggtg atggagggcg gacgtttccg
   104581 ggcgatcggg acaccctgcg aactgatcac ggacaggtcg gtcgccgaga ttgtcatacc
   104641 cgatttttcc gggatacgtt cttcgttccc ctgcaggcca cacgagggag agaatccggt
   104701 catctccgtt cgtgacctcg ggttcctgta tggtgatgtc cccgcgctgg caggagtctc
   104761 gctcgacgtg tacccggggg agttcgttgc catcgttggt gagaacggtt cgggtaagac
   104821 aaccctgatc aagcatttca tcggtctttt gcatgcaacg aggggcagtg tcactgtcga
   104881 cggaaaggac gcaaaggtca ctcccgtgtc agagctggca cactcggtcg ggctcgtctt
   104941 ccagaaccct gaccacatgt tctttgcgga taccgttgcc ggggaggtca tgttcggaat
   105001 cacgaacctt ggtatcccgg agcccgaagc agtcctcggg gaggtccttt cgcggtgccg
   105061 gctctcgggt gcccgtgacc tctatccccg atggctctcc cgcggggagc gccagcgcct
   105121 cgcgatcgcc tgtgtccttg caatgcagcc gaaggtgatc gtcctcgacg agccgacaac
   105181 agggctcgac gggaaagaat cccgggaggt catggagatc ctcaggcagc tccaggcaga
   105241 ggggcgggcc atcgtgatgg tcacgcacaa ccacgagatg gcccgggagt gtgccgaccg
   105301 ggtcgtgacc atgagagcgg gcaggatagt atcagacacc cggaacgggg cgtgaaaggc
   105361 catgggtgaa atcctccagt acattcacaa ggacggtctt tttcaccgga tgcatcccgg
   105421 gacaaagatc ttcttcatcc ttgtcatcgg gataatggcg atcctttccc tctccatccc
   105481 gttcctctgc gcactgctgg gagttgtcct cgtgatggca ctcgcgggac gcattctccg
   105541 cgaagtgctg gaccagatga aactgatcct ggcaatgagc gtcatcttca tcctcatcac
   105601 gctcgtcacg atgccggaag gagacgttct tttccacctc ctccccggtg gccttcttcc
   105661 cgtgacaacc ggagccctgg acgcgggtat catcctcacg ctcaggttcg ccatcctcat
   105721 catggccttc cagatcttcg tcatcacgac gcaaccgcgg gatctcgtca acaccctgga
   105781 gaagatgcgg gttccgattg aatacaacct gatgttcctg attgccctcc ggttcatccc
   105841 gaccctccag atagaggcac ggaagatcca cgaagcccag ctcgccaggg ggtattccac
   105901 cgggaaaggt tttgtcggga ggatcaggag cgtggccccc gtcatggtcc cgctcgtttc
   105961 aaacgccctc tcccgggcaa atatcctcgg gattaccatc gatatgcgcg ggtaccggac
   106021 ccggaaaaga acgccgatcc gcgaggaacg gctcaacatg ccggacaagg tgttcgtcgg
   106081 ggtgctcggt ttcgccctcg cggcctacat tgccgcaacg ctcctgcaaa tcctgcgatg
   106141 accgggattt aatcaggcct tccttccatc atcacccggc acaggctggt tcttcccgtc
   106201 ctctcctctt ctcccttccg gggaagcatc tatgggtgtg taccccgaac aggataccgt
   106261 atgaaatacg agatccggta cagacccgca tactcgctcc ttgtcgtcac cctctccccc
   106321 ggcgagagca tcgctgccga gtcagggtcc atgacgtaca tgcagcccac cctcaccgtc
   106381 aggacgcaga agcgggaaaa gagcctgctc ggttcgcttg gcctcgccct cgcgggaggg
   106441 cagagcttct ttgtcaacga gttctgtgcc acgacggcag caggagaggc aggattttca
   106501 gcagcgcctc tgggcgacat cgggaccctc cgggtgagcc ctggaaaggg ctgcatcctc
   106561 cagaaatctg cttacatcgc ttcgcaggga actgtcgatc tcgacgtgaa atgggaaggc
   106621 ttttcaaagg gtctgttcgg gcagggactc ttcatgatca gggcgaccgg ggaggggacc
   106681 ctcttcatca atacgttcgg ggcaatcgac cagcacaccc tcaaagaggg tgaaagcctc
   106741 atcgttgaca atttccacct cgttgcattc agcgatacct gcacgtacca ggtcaggaag
   106801 ttcgggggga tcaaggagac cctcctgagc ggtgaaggtt tcgtcacgga gatccgggga
   106861 cccggcgatg ttttcatcca gaccaagaac atcagggagc ttgccgaatg gatctggaca
   106921 ctcatcgagc cgagggtcca ggccagggca cggtaggagt ccctccctga ctgcaggggt
   106981 ttggttcctt tcccggcccg gcaacaccgg aagatccaca gccgctccac cacccgctgc
   107041 aggactctgc taaccggtat cccgggatga tctccgggat cctccgcaac ttttttctcc
   107101 cggtaccggg catctctccc tcatgcccac gtgcagtgac tgtttcctct acgtcccggg
   107161 aaagggcgga aaggacggtg agtgccgtat caacggtccc gctccgccgg acagggatgc
   107221 agagcggtgt ccttcgcgga cgttccgccc aaggcagtaa gtctcctttt ttacgctcct
   107281 gcccggctat tcaggaagac tcctctggcc tgccggtctc tttccggccc tctccggttg
   107341 cagtaaagac aaagacaaag agtgtctctc cctccatcct gtattccgaa tagaccgaac
   107401 aggaaaaacc ctgccccgag aaggtatcgc ggacgcggga gggatccgaa agcgaggaga
   107461 cgaggaggag gatgcgcccg cccggtgcaa gaacccgccc cacctgcgct gcaaacctcc
   107521 tgatgactgc tgtcccgtct tccccgccat cgagggcata cccgagccag ccgtccaccc
   107581 tctcgtcggg gcgcgtgggg aggtacgggg ggttgaagat gaccgtgtcg aaggggcccc
   107641 tgatcccgca aaggaggtca gcccggacga catcgatgac cccggcctgc ctcgactgcc
   107701 tgagtgcatg ggggttgata tccgtccctg tcacttccgc ccgggatgca agtcgtgccg
   107761 aaatgaaacc gctgccgcac ccgacctcga gcacgcgttc tccgggggcg acgagggcga
   107821 gggctgcacc gaggaggagg aacgtgtcgt cgtccggggg atagacctgc cagtgcctca
   107881 cgatgcaccc atgtttgcaa tcgtcgcgaa atcctcgagg tacagttcct ccggccttgc
   107941 cgcgaggatc tcttcaggga ggtttttgac aagaaactcc gcaagtccgc tttcgagcat
   108001 cgaccccgca ctcttcaggg agttgcgcac ggtcttcctg cgatgcgaaa agagtgccct
   108061 gaccacccgt gcatagagat ccctgtccct gatgggaaag agcggttcgc gggggacgat
   108121 gtggaggacc gttgaccgga ctttgggcct cggtgagaag gcctgtggtg gcacatcgaa
   108181 taccctcccc acggcacagt acgtctgcac catcacggag agcctcccgc actccggggt
   108241 tcctgccggt gcaagcatcc ggtcggcaaa ctcgctctgg tacatcagga ctgcttcttc
   108301 aaagccggtc tcgaggagac ggaacgtgat cttcgaagag gctgaatagg ggaggttgga
   108361 gacgacgaca tcgaacccgg gcaggggaca cgagacggca tcgccgtgga cgacgacgag
   108421 ccggttttcc ccgatttcgc gcaaaaaccg ttcggagagc atttccacga ggccggggtc
   108481 gatctcgact gcaacgaccc gtgcaccccg ttcgagcagc gcttccgtga gtgccccccg
   108541 gcccggtccc acctcgagga caatccgccc ttccaccctg atgatgcctg caatgcgctc
   108601 gatggccttt ctgtccacca ggaagtgctg gtcgaatcgt gcactcatcg ggacgtgaac
   108661 aggtgatact tgacgttggg gtcctgcagt tcctccatca cccgtgcaat gatcatctta
   108721 tccgggtgag ggatcgactt gatgcgctgg ctgatatcgg caaagctctc gaagggtttc
   108781 ttctcccgct ccccgagaat ctcccacatg agcttcttgc ctatcccggg caggagatgg
   108841 agcatgtgga gcttcgggct gatggagatt gacttgttga agaactggac gaactcgctc
   108901 tccttctcct tcacgatcct ctccacggcg aagggaagtt cgagtttcgc agtctgggtc
   108961 agatcgttgt aactgatcct gcgcttgacc ctctctatct tctcccgctc cccgtcaccg
   109021 atgtacacgt tctcgtggat ctggatatcc gttgtcttgg ggacgagttc gaggagcttg
   109081 aactgagcaa caccgacagc ctggacaagg ggttcccgct tgaaaaccgg ccggggatcg
   109141 tccggatgcc ccttcataag gacatcgagg actatagcgt agatctcctt cttttccgtc
   109201 ttcatgaggc caccttcaga aatgggcttt gaccaactcg atgatggtgt ccagttcctc
   109261 gggctggagc gtgtattttt cctttgcgta tatcgcccgc agctcgtccc gggtccttgg
   109321 catgatgttc gcgatgcgga acgcgatgtc cggtttcatc ttctcgagtt tctgcagttc
   109381 ggtgaccagg agacgggact tctcgctcgt tgtctttgac aggaggttgg catgctcgat
   109441 actcttgcgc agttcgtagg acatctccct gcctgcctct atccgctctg cttccacttt
   109501 cgaaagcacc tcgcggagct cggggagagt gatcctctcc tccctgataa ttgcctttac
   109561 tttcatgcca cgcctccccc gggtatactc ctgtggagtg tttacctttg ggcttttaga
   109621 tgttgtggtc tggcgataac gatcttttcc tttccaccat cgcggatgga caggagccag
   109681 gccctgcccc tctggccgac aacggttcct gtcatgccat ggaaccggcg gtggggcatt
   109741 cccttctgga tactgggttc aacaacaaca tgaaccttct ggccgatgtc aaacttctgg
   109801 ataagcgagg ttacagggac gattccctgc ctgcggatat ccttcttgaa cttgtatcgt
   109861 gtcttcttgc gtgggccgtt gtgatgtgcc atgtcttact ctccctcgtt gttaccctgg
   109921 acgtagacca cgtccagctg gcaaacccgg gcaggtctcc ccaggatgcc ggagaggctc
   109981 ggctgggtgc gcccctggtc cccggagacg agttccttga tgtacaagcc cgcctcaccg
   110041 gtgatctcca ggatgaccct gccgttctcc tctcccaggg cacggatatc gatgacccgt
   110101 cgctcccgca cgcggtcggc acggcggtgt gcgacccgca gcggggtgcg ctggttcact
   110161 tttgcccctt taagggctct gattgcagat tgaagttcat cctgtgtgta tgatccttca
   110221 atctcgacca ggatcctgta ttttttataa cccttggctg atttaataat ttccacatct
   110281 tccctttttc cccagcgttc gatggaaaca gtcaccttcc ctccggcttc cctgttgatc
   110341 ccgtcctcga ggtcccggag gtcaacggaa cggatgcggg gtgcgacgac ctccatgacg
   110401 aacggacggc ccgatccgac catgagggca tcgatatctt ccctccctgc cccgtggagg
   110461 atggcatttt cagcagaaaa gaggcgtatt gccggtctcc cgatgatctc ctcgaccgaa
   110521 tcgggatact gtttccccgt aaaaccgcac ttttcgcacc ccgcccccct gcatgcccgg
   110581 cagtcccagt gtgtctgggg aagccccctc tccagcttgc agtaacggcc gcagaaaaag
   110641 acggggttga cctggacttc aacggtctcc cccggaatgt cgaggatcgc aacgacgtcg
   110701 ggactggccg ggtctgcagt ctttcccgtc aggcgtgcaa cggccttccc gacctccctg
   110761 ttcatctcgg acttcagggg ctcggcatgg caaagatcga gatcgctcca cacgatctcc
   110821 tcgctctccg ccacgagtgg cggcacacgt gtcccgatgg caaacttttc gtactcgagt
   110881 ccctggaggg ccctggtcac cctttccgcc cactcgggaa cgcgggagag gaggcccccg
   110941 catatccagc aggtggcggg ttccgcgaag ggccggttct cctgcaggaa aacagcgatg
   111001 cggagggcac gccccctctc cctgttggaa aggccgtgcg agagcttccc gaagaacctg
   111061 cccaggcagc tgtcgcatat ttcgccgtag gcaaggatgc gtaaagcaag gtccgttacg
   111121 tccatcctgc cctcctgcgg tcgatctcgt tgagaaggac aatgattgca tggtcagcat
   111181 gcagcgtggc cggcccgacg gatatcctct tttgcccttt gaggagggca tcctcttcgg
   111241 ggtaaaaatc gaggtggtca ctgaggatat agttctccgg gaggctgctg catgcccgga
   111301 tatcctctcc cgactcatcg aggaccgcga agggcgccat ggaaacgagg tctgccggac
   111361 ctcccctctt cacctctact ccgggggagg actcccggaa ctccgtgccc gcgggaattg
   111421 ccagtgcctt cctgatcagg gcaccggcac tcctttcgtc cgggttgagc gaacgcaggc
   111481 ggtcacccat gaaacggacg atcttgtccg ggccgggagg cccccggagg agaaggtaac
   111541 attcgacgtc cctgcgcagg ctgtgcgaga gaaaaaacgc agagttgatg cacctgcaca
   111601 tgatgtccat ccggccggcg ccgcccggca tgtccgagag ggaaaaatct ccggcagtcc
   111661 gggcgaggtg cccgataacg gcgatgcgta tcatgaacgg ttaagtcccg ccgccgaact
   111721 ttttcagcat ccgctgcatg ttgaaccttc cctggccgcc cctgaccccc ttgagtgccc
   111781 tcttcatcat cttgtagtag cgcaggagct cgcgcacctc ctccggggac gcccccgccc
   111841 ccctcgctat ccgctggata cgcgaactcc cgatgacgga cgggtcgtcc atctcggccg
   111901 ccgtcatgga gtccatgatg atccggtaac gctgcatctt ggtactggtg atatcgtagg
   111961 catcttccgg tatctccatg ttcccgaggg gcagcatgct catgatctgc ttgagcgggc
   112021 ccatacgcgt gactgcctcg agctggttgt acatgtcgcg gagggagaac ttgccccgca
   112081 gcatggcatt gacgtccact tcagctgccg caagcgtctc ctctgccttc tccacgaggg
   112141 ctttcaggtc acccatgccg aggagccggg agatgaaccc gtcgggatcg aacctctcga
   112201 ggtcatcaat cgtctcaccg ctcccgatga agacgatccc tgaccgcgtc tctgccactg
   112261 ccgagagggc acctcccccc ttggcagtcc cgtccatctt cgtgatgatg acaccgtcga
   112321 tgctgattgc ctcgtggaac ttccgcgcct gctcggcagc ctgctgcccg agggccgcat
   112381 cgatcacgag ccaccggtgc tgtgccgatg caattgcctg gatatcgatg atctcccgga
   112441 tgaggtcgct ctcgagtgcg tgccgcccct gggtatcgat gatgatgact tctgccgatg
   112501 acagtgactt gaggccttcc ctcacgatct tcagggcatc cttctccccg gggttcccga
   112561 aacacgggac atggatccgt gaacagagcg tgttgagctg gtcgaatgca cccggccgga
   112621 aggtatccgc gcagatgacc gcgacgcgga gccccttgcg ctggaagtac cgggccagct
   112681 ttgccgtcgt ggtggtcttg ccgctcccct ggagccctgc catcaggatg acctggggct
   112741 ccagctttac ctcgccggca gaaccgacca gcctgacgag ttcctggtac acgatgcgga
   112801 gaacgtgttc cctgacggtc atcccttttg gcggctgctc ctcgagggca cgtttcttga
   112861 tcgcctccga gagctgcatc accagccgga cgttcacgtc tgcctggatg agtgcccgct
   112921 gcaggtcccg gaccagttct tcgacggccg ccctgtcaac gaccgtcttg ccggcgagct
   112981 tctttactgc atccttgagc gacgtcccga ggcgatcgag catcaggcac tcaccccgag
   113041 gagttcctcg acgacccttg ccggggagaa cgggacgata tcgtcgtatc cctgccccgt
   113101 accgagaaac atgacgggct ttccgatcgt gtgtgcaatg gagattgccg ctccgccgcg
   113161 ggagtccatg tcagccttgg tgaggatcac cgcgtctgct cccactgtcc tgtcgaactc
   113221 gtgcgccctg atgacggcat cgtttcctgc caccgcctcg tccacgtaca cgatgaggtc
   113281 agggttcatc accctgcgta tcttttcgag ctggttcatc aggtttgccc ggttgtggaa
   113341 cctcccggcc gtatcggcaa ggaccgcgtc gatcctgtgt gctttcgcgt aactgacggc
   113401 gtcaaagaga actgcagagg gatccgctcc ctgctggtgc tggatgacct tgatgccgag
   113461 gcgatcggca tggacatcga tctgctcgag tgcacctgcc cggaacgtgt cccccgcacc
   113521 gatgacaacc gagaaaccct gctttttcag gtaggctgca accttggcaa cggtggtggt
   113581 cttacccgta ccgttcacac cggtaaaaag gatcctgacg gggcgctcgt ggttcctgat
   113641 atacgagacg aggtcaaaac catccccaag aacgctcatc agcgcgtttc ggagcgctgc
   113701 agtaacgatt tcgtggaggg gttccccaat ctttctccgt ttcccagtca ggtcctccct
   113761 gaccctccgg atgatttcat cggccaccgg gagggcgaca tcgttctcga gtaggaccat
   113821 ctgcagttcg aagaggggtt cctcgacatc tttctccgag ataaaaaatt ccctgtctgt
   113881 aatgaggact tttacccgcg agaggaggga aggatccttt tttgccgcct ccgcaggtgc
   113941 cgcaccaccc gggaccccgg ttttttccac agaaggttct gcagggatgg tctgctcgat
   114001 cctgtcttcc agggaccctg taatcttctg gagcctggac cggagcccct caaacatcgt
   114061 tcaccacgac cctttcagcc gccgggttcc ccgccctgtg cagcccgtgc ctgctgcgcc
   114121 tggtactggt gataccctgc ttcgagccgg cggcctatct cgttcatctg cgcgcgtatc
   114181 tgctcgaggg tctccatcac cttctttgcc gaggcttcca tctcggtgat gcggtctttg
   114241 aggtattcga ccgcttcttc cgtcgaacgt tccacgacaa cctctgaacc gatgctgacg
   114301 aggacgcgac cgggattctc gacccgggca cggacactga tccctgctcc catctggagg
   114361 aggactgtgc tgtcgggaga ttccgcaatt cccttcacag cctctattgc agacatcgct
   114421 tcaaccctcc cttcctcgag gagcgcgagc tgctgggaga atacctctgc ctgctgcctg
   114481 tattcgttga ggtatatctg cagggactgg agttcccttg ggtcgattgc gtccacgcta
   114541 ctcacctttg agcagggtaa cggagtggat agtgatatac cttcttttta cacggtgctt
   114601 gcttccaaac agagtgaacg tgcgttcctt tgcctgcatt tcactcggtg cctcgatgat
   114661 ctttgagaac gggcggacct cgccgcccat cctgaaatcg ccttttacct cgtacttctg
   114721 ttctgccatt tcctctcact ccagaaaacc aaaaacatcc tctattcgtc ccagctcaaa
   114781 gccggttgtc tcgagtccgg cgacgtatcc cttcgaattg acgaggagcc ctgtcccgac
   114841 gagaccggta cccccgttca ctgaccccgt gccaacagga agcccggaga cctcctccac
   114901 cctctgtatc tcggccctcg tgcaccgggg atggacgagg acccccttgt tggtggccac
   114961 accggccatg ccgacggtct tgacgccacc cagcgtgagg ggcacaacct tcacgccgag
   115021 gaaatccccg atctcgcctg ccatctccgc gggcatgtcc gggtggaccg ccgcaaacga
   115081 gtcattggcg aggatgacgt tgcctgccgc gttcatcgtg tgttcgagca ggtatacctc
   115141 ccggtattcc cgaaggatgg agatttcctc gtctgttgcc atcccgctca cgacaaaacc
   115201 cctcgcgttg cccgtgagca gggaaccgat gatctcgctt ccctggaccg tggtcgggat
   115261 aatctcgact cccagcagct ccctgagtgc ttccccgaac tccgcgggag ccgagggggg
   115321 gattaccgcg acgtcgtcca ggacacggga gaagacccct atgtggggga ttcccccaaa
   115381 cgagatcgtc ctttccatct cactcctctg cgagctcggc ctggacctgg ccatcgtcga
   115441 acttcatggc ccttacccgg atccgggagg ggggcttttc ggaaccccgg tcccagacac
   115501 gctcgttgat ggtccggtcg agtttgacgt cgctgctctt catgtgccgc gcaaggaact
   115561 tcctgatatc cttgatggcg gtgttgctcc tcttccaccg cggtgccctc ttcgcttcgc
   115621 gcagggggat cacgtagatc tgttcctgga ccttctctgc catggtgacc tcacaccttc
   115681 aacgtgctcc gtctccagtt ccgcctgcgg gggtgcgttg tgacctggcg tttcgtccgg
   115741 gccatcaccc atgcaggaac cctgcgattc tgctcgcacg ccttcgcgag gcgtaccttg
   115801 taacctttcg ttgatctgct catggaaatt tcacctcatc ctctcgtatc tgccggaccg
   115861 atgaccagtg actgctcatg gaacatgggg aaaaagcggg tggcatcctc acccctggca
   115921 cggacagcct cgcgcagttc cacctcgtag tcaccattct ccagtgtgcc cgtctcccca
   115981 aggattactc tgaggtaacg gcctgccagg cgatcgactt cccggcgggg atacccgaga
   116041 agaggccgga cgtaggaaca accatgggtg tcctggaggg accgggcctc gtccctggaa
   116101 agcatgggaa cacggtcatc gaaccgcgtg ccgtctgcaa caaccctgta atgcgatgca
   116161 aggtcgtgga gtgcggcttt atggaccatg gtgattgcct ctgcgggata tcccctctcc
   116221 aggatggaat cgaccgctgc tgacagcagg cccgggggaa agaccctgac tttccagggt
   116281 aacccgagtg cttctgccgc cctctccacg gcggaaaggt ccctgttctc cccgaacacg
   116341 tacgtgttca gctccacggt ataatcgcgg gagaggagga ttgctgccag ggaactgtcc
   116401 ttccccccgc tgaagaggac tccggccttc atcctttcct ggtaatcctg aaatcctttt
   116461 ttgcaggcag taactgctgc agcagggact tcaactgttc gtcagtgatc ttctgcgtga
   116521 gacgaccgct gtttgccagg aggacgagct gctgctccac tgcccgtgca aaatcagggc
   116581 gcgtgagctt gatggtattg aggcgttcac gtgcctcggg ctcgagaatc cggagaagga
   116641 cggcatggat ctgcgactcg atctgcctct gcctctcggc ctcttcctgc agcagctgct
   116701 ggtcgtatgc ctgctgctgt aactgggcca ttctcctgcg ccggagttcc gcaagctcgt
   116761 cgtctcccat gggtcattcc tcactgcgtg gcctgtgcct tttcttccct gactatcttg
   116821 tcagccaggt tgtccatgaa cgatatacca ccggggctta cctttctccc ggtcttctcc
   116881 ttctggatca acccggctgt ctcgagctgc tggagggcct tgcgcaggat ggacccgctt
   116941 cccttcctga actgtttcgg ccgggatccc cggtccttct tgcctccgta aatcgtgcgg
   117001 agtcgctgta ccccgatggg tccctcgatg tagacccgcc ggaggatgga tgctgtcctg
   117061 acgaaccacc actcggggtc atggggaggc atctccttgt gcactcctgt cttggcaaat
   117121 gctgcccagt caggaggctt catctccggt tttttcttca gttcctcggc cagggtgcgg
   117181 atgaacctgt ctgccgggac gtcatagacg gttgtcatac ctggtataac ctcactgtca
   117241 ccgattggaa tgaacagtct ttactatttt gtgtgctgta cttttatata tttcgagcat
   117301 ggagccctat tcgcggcgac tgccggaaat atcccggatt ctatcccttt ttgtgttcct
   117361 cgagcactgc agtcctgcct cgtaccatca ccagccgggc acgggtactc ctcgcgaggc
   117421 tctgggggtc aaagtccgcg ttgcgcaacc acttcacctt gaccctgtgc ctcctttcga
   117481 gctggaggat gacctcgctg atcaccgatt ccgaaagacc ctgctttcca atccagacag
   117541 ttgccttgag atcctgcatc gcgtcactgc cctccattca ggacctcctc cggagggggt
   117601 acctcatctg ccggtggcat gcaaggcacg tgactgtaac cctgccgcgg tatatcctga
   117661 ctctcgcgtt ggccccgggg gcgaggaacc ggtggcagtg gtggcagaac tgccttcgga
   117721 actccctgtc gagccggacg cggtgtttca ttgatatctt tcgggccagc gagacatacc
   117781 tgtctgcaag ggccggatcg aggggaaatg ccttcctcgc ctgttcaaag aggatggcta
   117841 tcctttcgcg ggcgatgcgc cgtgcctcgg ggtgtgctgt tctcctgctc atggaaatgg
   117901 aagagagaat tatcactctg gtgccgggac gagatatacc tttatgcagg cggggcagaa
   117961 tcctcgccga cgatggaaac cctgcgacca ctgaccctga tgcggtcttc gcagaatgca
   118021 cggattgcac gggggaggca acggtgctct tctttgagga tccgctcgga caggctctcc
   118081 tcgtcgtcgc cggggagcac cggcacgcag gactggacga taatggggcc tgtatccaca
   118141 ccctcgtcaa cgaagtgaac cgtgcacccc gagaccctga caccgtattc gatggcctgg
   118201 cgctgggcat gcagccctgc aaaactcggg aggagagcgg ggtggatgtt gatgagcttt
   118261 cccggaaatt ccctgacgat acctgcaccg aggatgcgca tgtacccggc aaggacgaac
   118321 aggtccgcat gcagggactt catgacccgg agcaggtctg cctcgtattc gtccttcgtg
   118381 gaataccggg aataatccac gatgaagacg gggataccgg cactcctcgc acgcgtgatg
   118441 gcatacgctc cggggttatc ggacacgagg ccgacgcact cggccgggat ggagccctgc
   118501 ctgatagcat cgatcacggc ctggaagttt gatccccttc cggatgcaag ggctgcaata
   118561 cgtttcattc tcctttctcc ccgccctttt catctcccgg ggggtgcacg atgatcttga
   118621 ccttcacgac ccgccgggcc agcatctggg tcaccaccag ggttacgtgg cattccctga
   118681 tgtatacgct ctcgcccgga tgggggatgt gcccgagccg ctcgatgacc agccccccga
   118741 tgctctcgta cgattccgag acgggaaggg agagatcgag ttcatcgttg agttcttcaa
   118801 cccagacctt tgcgtcaacg aggtaaaccc cctcccctat cttctggatc tggggttctt
   118861 ccctgtcgaa ctcgtcgagg atgtcgccca cgagttcctc gaggatgtct tcgacggtca
   118921 cgatcccgac gaaactgctg tattcgtcga gcacgatcgc catctggacc ttccggagct
   118981 gcagttcgcg gagtacctcg tcgatcttct tgctctccgg cacgaagaag gggtcgtaca
   119041 tcaggtcccg gatgctgacg ttcttctttc ctgagagcat gctcgaaaag acgtccttga
   119101 cgttgaggac cccgatgatg ttgtccatgt tctcgtggta gacaggaata cgggaaaacc
   119161 cggtctcgtt gaagaggtgg agtgcttcct cgagggtgct ctcgtcatcg atgagagcca
   119221 cgtccacgcg gggggtcatg atctcccgcg ccgtcgtgtc accgaactcg agcacggagt
   119281 agagcatctc gcgttcctcc tgctcgattg ctccttcctc cttgcccacc tctatccatt
   119341 cctttatctc ttcctccgta acggagggct ctgctgcccc ctcctccccg gagtccttcc
   119401 ttttcaccct tcctatgacc cataccagcg gcgagaagac gatggagagg agatatatcg
   119461 gtcgggcaac ggcaagggca tatttttccg cgttctttgc ggcatacatc ttcgggctga
   119521 tctccccgaa aacaaggagg aggatgacca ctgcaccggt tgcgatcccg acaccgatat
   119581 tgccgaagat gctgatcgtc accgcggttg caatcgatgc ggcagcaacg ttgacgatgt
   119641 tgttgcctat caggatggtg atcaggaacc tgttgggatc ttccttgagg cgtgcaagga
   119701 catcggcccc gggccttttc tcattgacaa gagtccgtac cttggcacgt gtgacggaga
   119761 ttaaggccac ttctgatgca gaaaaaaaag cagacaacac gaggcatatg atgaacagca
   119821 aaaggaataa aaagtcctcg atcatcaggt ccacgccgac tgaacggctc ctctcatcat
   119881 tttcatgtgc ccagtgacac tctatctatc gcactgacat tttataaatt cgtcgattcg
   119941 ccgaagaagc ctttcataaa tcctgattcg tgcgagagga gggctatctt ctgccggtac
   120001 gagagcggcc ggggcagggc aaggtcctcg atctcgagcg tgaggtgccc ccggtacgcc
   120061 gaccgggaaa ggcggtccag gacgcccgac accccggggt cgcccgacgg ggggagatgc
   120121 atccttccct cccggcctgc actcacgtgg acgttgacga gccggtcacc gcaaaggtcg
   120181 atgtagcggg atgccacgcc gggtccgtca gccattgcgt gggaaaggtc gagcgtgaag
   120241 gagagccatt cctcgcggtc gaggaggtcc cgcatgcctt ccggggtgct caccagtgca
   120301 ttgatgcggt tttccatgtt ttccatggca actttcactc ccgactcccg cgacacctcc
   120361 tccagtgcac ggatgtaccg ctcgaacttc gcacaatccg cgggtcccgg gggtctcttt
   120421 gcagtcctcc tgccggggtg gacagtgacc agcggaaaac ctgttcctgc cgcgagcctg
   120481 acagaatcgc agacgaaccg gacggacacc tcggcgatga cggggttcac ggaggtcggg
   120541 tttaagtcga ggataggtgc gtgcagggtt gccctttcca tgaccgggta cacatccctg
   120601 gcttttttga tctcgtcccc tggctggcct gcaagccaga aagccggtgt ctccacccag
   120661 aattcgacag aatcgagccc ggccgcgcca acggcggaca tgatctcccc gatcgtgtat
   120721 tcgtgaaaaa acatggtgga gactgcaaaa acgaccatga tcctatttca taacaacctg
   120781 cccataatta agtgttgatg acccggaatt cccctggctg cggcatggac tctcccgggc
   120841 acccgccggg aatcttctcc gtctcggagg tctcctccct catagggtca ctcctggatg
   120901 acgtccgtct ccatgatatc tggatcaggg gagaggtcac caattacaag aaccacacct
   120961 ctggtcaccg ttacttctct ctcggggaga aggcgggtga gaggaacgca ctcatttcct
   121021 gcgtcatctg gaggacggat gcagcacggc tcgcgtgtga gctcgccgac gggatggatg
   121081 tcatcgcgtt cggctcggtc ggccactact cccccggggg gcggtaccag ttctatgtcc
   121141 gggacatccg ccctgccggc cggggcgaga aatacctcct cattgaacag tggaaagcgc
   121201 agctctccgc agagggatgc tttgatatcg cgcggaagcg gacgctgccg cctttcccgg
   121261 cccgggtcgg ggttgtcacg tcggagacgg gtgccgttct ccaggacatc cggaacgtta
   121321 tctcccgcag gtgccccgtg gaactcgtcg tctcgccgac tgccgtgcag ggagaccttg
   121381 cccacataga gatatcgcgg gcgatcgggc gacttgcagg actcgtcgaa gtcatcatca
   121441 tcgcccgggg cggcggcagc ttcgaagacc tcttcccctt caaccaccct gacgtcgtga
   121501 gggctgtcgc ttcctctccc gtcccggtgg tcagcgccat cgggcacgag gtggatgtca
   121561 cgctcgccga ccatgccgct gatgtcaggg caccgacccc ctcagcagcg gcagaactcg
   121621 tcgttcccga aagggtgaag atcctcgagg aactgggcgg gatacgcaag ctgcttgccg
   121681 ggcgcctgct cgcaaaactc gacagggcat cagccgatct tgccgacttc cgggagaggc
   121741 tctcagcccg ccggatggga cagcgcctga ctgtccggag ggaagacctc tcggtcctcg
   121801 aaagcaggat ggtgcgggag atggagtccc ggatcgcccg ggaaaaggaa cgcctcgcgg
   121861 gatattcccg cctccttgcg gccggcaacc cggtaaacct gctttcgagg ggttactgca
   121921 tcatcacgcg ggagaagaag gtcgtccgtt ccatccggga aatgtcaccg ggggaccgga
   121981 tttcgatacg gatggcggac ggttccgcag aagcacgtgt ggaggaagtg taccatgaca
   122041 cagacgtttg aagacctgat gaaggagatc aaggagattc tccagaaaat cgaggacaac
   122101 cagaccggcc tcgacgaagc aatcgcgctc tacgaaaggg gcgccgtcct gatccggcag
   122161 gcagaagaga tccttgccgg tgccgagatg aagataacga tgctcgggcg ggattaaaac
   122221 cccctttccg gtcagggaac gctgacctca aaagtcacga tgaccggttt ccctgctgct
   122281 acttgtgcca cgaaatcgcg gggaaatgtc cgggctgcac cgtcggcaca tatcgcaacc
   122341 gtcctgtcgc agacaaaact gctcctgcgg aagaccatgt catccgggtg ggagagagtc
   122401 atcctgctgc ttccccgccc ccggacagtg acgacctgcc cctcgcagca gaatcctgcc
   122461 gtgacaacgg catcatcgcg gcagaggagt tccctgacct cccggggaag gtcacgtgcc
   122521 gccatgtccg ctgcaatccc gatgatgcag tcacccctcg gggtaagctc tgtatccctc
   122581 gttatctcga gggtggtcgg gtggagcgcc gtgacgaacg ggtggccctt gcaccggatg
   122641 gtgacacgtg caacgccggg catggttgga gtgatgggtc ccggaatacc agaaaagttg
   122701 cggtccggga aaaaaggaac ggtttttccg ttcagtactt gtaccacctt cccttctcat
   122761 cgtactctcc ccggagcggc acggttgtgc ctgcctgcgg gacctgcccg agtatgtgcc
   122821 ggtagaagac agccttgaac gtgaggagga tgtttccggc aagggtgaac cagatgcatg
   122881 aaaaaagcgc ggtaagtccg attccgccgg ggccgagcat cccgttgaga gtctccatgg
   122941 tcagtgcctg cagttccccc tggtccatcg atgcaagagg aacgaggttc tcgtagagga
   123001 ggcctgtcca gatgaccatc aggggcaggg agacgaggat gacgatccct gctgcaacga
   123061 ggaagaacac gatgacctgg cccgggcggt tcaggacgat ttccacgctc ctcctgatgc
   123121 tctcgaagac acggcagtcc tcgaagaccg cggcacagtc gaagaagaac gtgaagaaag
   123181 cgatcgggac cgcacttcca aggatgatgt acgggaggac gagggtggag ttcccaagaa
   123241 acgagagggg tatggcaagg agcacgatcg ttgcaagtat cgaaaaggcg atgaccagca
   123301 acgggacgag gatcctgaag tagtaccgga tgcccccgct ccagaacgtc tgtggctcct
   123361 ccccggtgtt ccggatttct gaatatgccc cggcaacgag gaacgggact gccagtgcct
   123421 cgatgaccca cagtctcgtc agaaaaaaag tcccgaaata gtactgcagg acgatgtcca
   123481 ttgcggcaag acagcccacg acaaggccgg gaacccagag cacgggcttt ccgaggatag
   123541 tcgatactgc atctgccagc gcagcagtaa ccatcccttc accgttcccg tggcatcgcc
   123601 acgatctccc tgacctgcag gtcgaagaac gaggcggtgt gggcaggcct gatgacgcag
   123661 actgtatcag cgccgcttgc cgtccccccg accgcgatca cttcctcgtc cggcgagaca
   123721 acgccctggt ctgccgcaat gagagtgcat tccacggcaa ccttcagccc cacggcgatg
   123781 accctgcgga acgcttctgc aacggcctcg gtccgggacc cgcccccgac ctttgcagac
   123841 cgggagaatg cccgctcgag cccggagagg acgtgggtcc cggtgacgat ggtcacaccg
   123901 gccttctcca gtttcgcggc tgtttcgcgg gaaaactccc attctcccgg tttcgagaac
   123961 ccgacgacat gggtgacaac gatcagcctg atccctgtcc cctcaaggac acggaaaaac
   124021 tcctctgccg tctttcccga cgtgcttgca acgatgacct tcctgatgga gagttccctc
   124081 gccctttcga gggcgatttc tgcacagtcc catgtattct gggggccggg agcatcgaag
   124141 tagtaaacgg actttttcgt gtatgacata aggcactaat gttttaggtg gtaaaaggta
   124201 aagggaattg ctatgatcac gcttgctctt gccggaaagc ccaactgcgg gaagtccacg
   124261 ttcttccggg cggcaacgat ggcccctgca gagatcgcag ggtacccttt caccacaatc
   124321 gatgccaact tcggcgtggc ctattacagg actgactgtc cctgccgggg cctggggctc
   124381 acctgcggtc actgcacgga cggtatccgt tacgtcccgg tcaacctcat cgacgtggca
   124441 gggctcgtcc ctgacgccca caagggcaag ggcctcggga accagttcct cgacaacctc
   124501 cggcaggcag acgccatcat ccacatcgtg gacgcgagcg gatcctcgga ctccgagggg
   124561 aaccctgtgg aggcagggag ccacgatccc ctccaggatg tcgagttcgt caggagagag
   124621 atgacgatgt ggatattcgg gatactggac aagcactggc agaagatcca gcgccaggca
   124681 cagtcaaaga cctattccgt ccacaggggc atagcggata tcttcacggg tctcaaagtt
   124741 gcccccgagg atgtcatgga cgcggaaaga tccgcgggaa tcgaccttgt acacgcggac
   124801 caagcagcgc tcgtccggtt ctgcgaagag attgtccgga tcagcaagcc cacgctggac
   124861 gtcgggaacc gcgttgacct tgctccggac ggtctcgtcg aaaggctcag ggcagcgggt
   124921 cttctctttg caaccgctgc aggggaactt gccctccgga acgcagtggc cgcaggtctc
   124981 atccggtacc accccggcga cccggctttc tcggttgtcc gtgacgatgc actctccccg
   125041 gcacagaagg cagggctccg gacgatcgct caggtcatgg aaaagttcgg gggaacgggt
   125101 gtccagcagg caatcaaccg ggcgatcagg gatctcctgc acatgatcgt tgtctatccc
   125161 gtcgaggacg agcacaggtt ctctgactcg aagggaaggg tccttcccga tgcattcctg
   125221 atgcgggaag ggtcgacccc gcgggacctt gcctaccagg tccatacgga catcggcaag
   125281 ggtttcctgt acgcggtgga tgcccggaca aacatgcggg tcaaggacac gtaccagatg
   125341 aaggatggtg acatcatccg catcgtaagt acagccaaat aacctttttt tccggaaaaa
   125401 gacggtggat cggggctctg gtgcaaatag gtttatatag ttggaacagt aaccgctgta
   125461 cagcaatggg tggcgagata taccaggcac agatcctgaa gaatttcttt gataccatca
   125521 caggcaccga caggaacctg acccggatct tcatgtgcgt cgtcagcctg gcgaagatac
   125581 ggatggagcc gccggaaaaa cttgcattcc tgattgacca gctgcgcaag agcaagatgc
   125641 acaaggaact ctctgtggac atcctggatt acatgtgcga cgttgccgcc cagctcgata
   125701 tcactgccgt ccagactgcg tttggtgcaa aggagatcgg tgaaatcgcc caggacttcc
   125761 gcggtatcag catggacagc ctctaggggc agaaaaagcg gggaatggtc agggcagggg
   125821 ggattttgat ccccggcagg gtatccccta actctccttt tccttatttc tggctgatga
   125881 ggttcctgta gtcttccagt atctggatga cgaagttctg gtgctcgtcc agtgactgcc
   125941 cgtcgtcggg agactggaga taggcaacag catagagcag gaggagggca ttgtcgagcg
   126001 tgtagacatt ccggtcctcc acctgctccg ggggtatgtt gagggcaagg aacgggatat
   126061 cctccttttc gaaggatact gccgagaacc cgcccggcaa cgactggtca agagcctccg
   126121 ccctttcctt tacaattttc aaggctcttt cgaggacagc cctgttctcc atctccccca
   126181 ggcgggagag agcccggcct gcatccgtgc cggcctttgc atagagcccg aacttgaacg
   126241 acaggacagt ggacgcgatg tcgtgggcac agtcccggga aacttttgaa aagaacggcg
   126301 tgatccggtg gatatagtca tagaggtact tttccattga tttttcctcc ttctcggaga
   126361 ttttgggagt gctgaagcgg aggtgaagcc tcaccgcaag ggcggtgatg cttgcggcat
   126421 acagtccctg caggagcagg gatggttttg tctccagggg cacgatgaag acaaagaggg
   126481 cgaacatggg ggcacagagg gagacgatgt ccttccttgg cttgatcagt gcaaggaacg
   126541 cgagcacgag ggaagcagcc acgctccccc agtaaaagtc tgcggcatcg gaaatgatac
   126601 ctgcattcac gagggctatt cccagcacca gtccgccgaa cgacagcacg gggacgagga
   126661 tgaagagaac cagcccgagt tccttcctcc gggtgtcccg atcactttcc gaaaacacaa
   126721 taccacatga atgtggagac gcgacgagaa aaagatttca ataccgcttc ccggcaagaa
   126781 agggtgcagg aatacgcctc ggatgcttta tgcgtcaggg agtggtacac tctcttcatg
   126841 aaggtgtgca ttatgtgcgg cggtgagggt acgcggctcc ggccactcac cttcgaacga
   126901 cccaaaccgt gtataccgat cgtcggccgc ccctcgatcc agcacctcgt ctcccacctc
   126961 tccaacctcg ggttccgcga ggtggtgatc accctcggtt acatgggttc tgccatcgag
   127021 aacgcactcg gggacggctc cctttttggt gtggatatca catacgtgcg cgagaagacg
   127081 aaactcggga cggccggcag cgtcaagaat gcccagcggc acctcgagga cggcaacttc
   127141 ctcgttgtcg ggggagacca cgtcaccgac ctcaacctcc tcgattttta ccgcgaacac
   127201 gcccggcacc gctcacccgt gtccatcggg ctgatcagca tcgatgagcc gggtgattac
   127261 gggatcgccg agatcgatgc cgacttccgg atccgcaggt tcaaggaaaa gccctcaccc
   127321 ggcgagatct tctcaaacct tgccagcacc gggatatacg tctgcacacc tgccatcttt
   127381 gacgagattc caccgggaac gaagttcgat tttgcacgtg acctctttcc ccgcctgatg
   127441 gaggggggac acacgctccg ggcctacctt gcccgtggca actggaccga tgtcgggaat
   127501 cccgcatccc tgcgccaggc ggagaagtgg aaactccagg agattccctt cacgagtatc
   127561 agcggcgatc tcacgatgaa ggccggccag atccagggac cggtccagat tggcagttca
   127621 ttcacgatgg ggaacggctc ccgggtcatc gggcccgtat ccatcggggc agggactgaa
   127681 atcgaggacc atgtccttat cgggccttac acgtgcatcg gcgggaactg ccgcatcagg
   127741 agccatgcaa aggtattctc gtcgtccatt tacgacaggg tgacagtcgg gaagaattcg
   127801 acggtatcag ggagcatcat cgataacgac tcggtcatcg gagatgactg cagcctcgag
   127861 aacgatacgg tcatcggccc gcgggtgacc atggagaagg gggttgtcgt ccactcgcgg
   127921 acacgggtct ggcccgaggt caccgtgccg gccggtgcag tgatccggga acacctgctc
   127981 aacgaagaat acgaggtccg gtgcgacggg tcctagcccc tgcggccgag gcgatgcgtg
   128041 atcgcgacca gcgggtggcg tgcgtaatcg aggatctgga tgtcgtcgag ggaacggagg
   128101 ttcatggcct ttgccgtcct ttccatcccg agctcgatgt cctcgttcac ctcgatgaca
   128161 taggcatcga gggcctttat ccccagtttc cgggcagcaa tcgcacggtg gtgaccgtcc
   128221 acgaggatga gccggcccgg tttcctgaca acgatgaggg gctcggcaag gcctttcctg
   128281 atctcgtata tcctgccctc cagttcgtcc tcgtatatcc gtgactgggt tggaacaagc
   128341 ttgtcgatcg gcacgacctc cctcctgagc tcggggttga tgccatggag tgtccgcagg
   128401 gtcgagatga aattgaagac cttttcagga gagacatgct cgatctgtga cctgatcacg
   128461 tcggtgttcg agatgatgcc gagcaggtgg ttgtgctcgt ccacgacggg gagtttctgg
   128521 atgcctgacc ggaatatcac cctcgccgca tcattgatgc tcatgtccgg gtccgccaca
   128581 atcagcttgt ctgacatgac atccctgacc ggggtatcag ggggcttgaa aaggagatcc
   128641 cgtgcggcaa cgtaccccac gacctctttt ccgtccacga caggaaaccc gtcatgcccg
   128701 gtcttcctga tcttgtccat gacctcctgc acggtcccgt ctgcactgac ggtgataacg
   128761 tcgtaggtca tgtagtcccg gacctttttc ttatccatcc catctcattt caggctggag
   128821 taactaaaaa ccatcgggaa aaaagtgaac aggaaaaaac ggggtatccg tcactctatc
   128881 ttgatccggc ttcccctctc ctccttcgac ttcttcaggc ggatctcgag gacgccgttc
   128941 ttgaacgttg cggatgcccc tttctccgtg acatcgtggg ggagcgcgac ggtgcgggac
   129001 atcgacccgt acatcctctc ccggacgtag tatccctcgt ccttctcttc cttgtccgaa
   129061 cgcctctcgc aggcaatctc gagggtgttc gggttcagga gagagatcga gatatcctcc
   129121 ttgtccacac cggggaggtc ggcaaccacc atgatctcgt cgtcgtgctc ccggacgtct
   129181 accctgaatt caccccgtat cgcagggagg aaccggtccg cgacaccggc ggccggcagg
   129241 aaccggcccc ctgtgcccca gaaccggttc tccatctctg taagcatgtc ctcaaagtcc
   129301 ctcatcatcc agccaaacgg gtatctcctt cggaatacca tatgaacacc tcctgtctca
   129361 ttcttcagcg tcggttttcc gctgactaac cttatgttaa tattcatagt atataaattt
   129421 tacttatctc ccttacagcc gctccatgcg acttacttcc cggggggttg gagagaagca
   129481 caccaggtgt ctcttcccgg ctcaccatca tgaaatgttt attttaacct gaaccaatca
   129541 agaatgaatg aaaaaaccaa agggaaagga gaagaaggca gggtccgggt ggaacctcca
   129601 gaagataggc atcatcgtca tcggggtgag ttttgcggtt atcatggtgg tgagttcact
   129661 cgggatgagc tggctcatca ctctcaatcc tgctgctgcc ggcgaccatg cgacggtcgc
   129721 tctcacgctg tacgacgaac agggccggcc cgtcctgacc agtgacctga aaaaattcaa
   129781 ccagacatac gaagcaggaa atactgtctg gctgtgcgga ccgttctcga tgtacgtggg
   129841 ccagacgagc tcgaaggaga tagtgccggt cccggttttc aattacatgt acggcgagtc
   129901 gcggtatgca ctcttctctg cggaatacaa tgcaatcgtg caggggattg ccgggatgaa
   129961 gcagggggag acaaaaaaga ttgccattcc gtcccttggg ggactggaac gcgagatgag
   130021 cgtcgaacag ttcgagggga ttggaggtaa cttcacggct gtcgttcccg gtgaccaggt
   130081 catcctcggt tttgccgagg aaccgggcgt cacggccggg accaacgaga ctccctccat
   130141 cgttatcagg acagggtacg taacgtcaaa aaccgcggac gggatcaggg tcaattttgc
   130201 ctatcccacg gccgaagtct ccatcaggga actgacgaag gtctgaaagc agagaatttt
   130261 tatagatacc attctttttt accttcatgg caatccgcgt tctctatttt ttccaggagg
   130321 ggtgcatggc ctgccacgag caggagccaa tcctcgcaga agtcgaatca gccctcggca
   130381 tccgtgcaga acggattaac cctgccaggg acagatcata tatcgcgaaa taccggctct
   130441 ccgtgacacc gacgatcgtc atcgagcggg atgacgcaac cgaaggggcg aggttcgagg
   130501 ggctcgtcca cagggaacaa ctcgaggaag ccatccgcgg tatcagccgg ggtacccgaa
   130561 gacccgcctg atcctttttg cttctgcctt ctgccccggt ttcctgagca tgcccccgtc
   130621 gcggatcttg atccgggaga ttcggaacct cctttttccg attgtataca cctccccgac
   130681 acagaacagt tcttctcccg gtaccatgac atggaatgac gtcgtgattc ctccggagtg
   130741 aattgcaacc cgtaacgcga cttcttcgac cttcctcgtc cacagagtcg agatttcccc
   130801 cgcgattgcc tgctttacac gcactccttt cgactcgatg gacgtgacct ccaccccggt
   130861 atactcgtcc ccgcacgcgg caacgaacgt gtcccccgtc cggcatacct cggcatcgtc
   130921 catctcgacc gtgcaaatcc gggacgaggg cccatcgctc acgattgccc tgacattcac
   130981 cgttttctgc ctttccccga caacgacggg atgcacatcg ccgcattcga ggcacctgcc
   131041 cacggggttt cgtccccgtg caacaagctc gtggtcagtc cgggcagaac agaccgggca
   131101 gaagtattcc tcgtctcctt ccctctgcat gtctcatccc tcataacccc tgcttcacat
   131161 ggcactccgg aagagtatca tgattgcgac cgacgtgacc cccccgccca gggtcgcgat
   131221 gaagttcgtt cccgcattgc cgatcagccc ggggttttcc atcagtgccc cgacaaggct
   131281 gtcgatattc gtcccgatga acccgcccag cgcacatgcc actgcaaccg ggaggtcgac
   131341 gatcccgagg atccatgcga ggagcgagat tgcaagggca cttcccatgg ccaccgcttc
   131401 cccccggaca gacacgcccc cgttggtccc cggcctgacc ttctcgaacg tcgtgatgag
   131461 gtatggatcc cctcccgtca cgcccagctc gcttgcaacc gtgtcagaag cagcagtcgc
   131521 aacgctcccg acaaagagag cgaggaaaac cggcgacccg ctcactcccc agaggacggc
   131581 agacgctgcc gagacgctcc cgttggcaaa gacattgaga taccccctcg caccgccccg
   131641 tccctgctcg attcccatct gctgcttgta atcatacctg taccgcgtgc tggctgaccc
   131701 gaggatgaag aaagcgagca tgacgatgaa ccaccggatg tctgcaaaga caatgaggat
   131761 gataccgatc agcgcacccg aaaaaagccc gctcacgtct gcggtgcgtg tccggtagga
   131821 aaaaaacccg aaactgaaag caatgatgac ggcgaacgcg atgagggcca gatcaacgct
   131881 gtaattgagc tcgtcgatga ggaacatcgt catcgccacc ccgagtgcct cgatcatgag
   131941 ggcgtcctct ctcctgcgga ggatagcctt gaggagaacg gcgaccacga tcccgaatat
   132001 gacgacgagc ggggcccatg tattgaagta gaacatgatg aggacgcagg caaaaaaacc
   132061 ggagatgatc tggaggatat aggagagcat ccggtctttg gcatcgtgga atatgacctc
   132121 ccccgtgacg aggatggcga gagtgcagga aaagacaaaa agggggagaa tggagagccc
   132181 gaacaggatg gcgatgggaa caagggcgat cgcaagcagc ctcgtccgct ggatgaggta
   132241 catcacgagg gaggagagaa ggacgatgac ggcaagtatc cacgggggct ggatgaaggg
   132301 tgcaatgagg acgaaggaga ggacgagcac ggtggcgagc ctctctccca tctggttcag
   132361 catcccattt ccgtttgcat cccgaagata agagttttgc ccggaacggg ttttggaaaa
   132421 agcatcccgt ttttcccgtg tatctgcccg gtttatcccg attgcgccgt gccatacagg
   132481 aattttgagt agattaggta tatctgctaa aaagttccat taccttgaga atgtcgccgt
   132541 ctctggatct ccccaagaat tacgagtttt ccgaggtgga aaggcgctgg cagagcgcct
   132601 ggcgcgatga gaacaactac tttgacccgg catccaaccg cccgaagttc atcatcgata
   132661 cgccaccccc gtacccgaca ggcacattcc acattggcaa tgccttcaac tggtgctaca
   132721 tcgatttcat cgcacggtac cgcaggatga agggggacaa cgtgatgttc ccgcagggat
   132781 gggactgcca tggcctgccc accgaggtca aggtcgagga gatccacggc atcacgaaga
   132841 acgatgtacc ccgggaagag ttccgcagga tgtgccggga actcaccctc tccaacatcg
   132901 agaagatgcg gcgcacgctc cggaggatgg ggttctctgt cgactggagc cacgagtaca
   132961 tcacgatgct tccggagtat tacaaaaaga cccagctctc gttcctccgc atgctcgccg
   133021 ccgggtacat ttaccagagc gagcaccccg tcaatttctg cacccggtgc gagaccgcga
   133081 ttgcatttgc cgaagtggca tacgagccga gggagacaac ccttaactat tttgacttcg
   133141 acgggctgga gatagcgacc acgcggcctg aactgctcgc tgcctgcgtt gcagtcgcgg
   133201 tgcaccccga cgacgaccgg taccgggaca tggcaggcag acgcctgacc gtgcccctgt
   133261 tcggtcacag cgtcccgctg atcgcggacc ctgccgttga ccccgatttc ggatcgggag
   133321 ccgtcatgat ctgcacgttc ggtgacaagc aggatgtgca ctggtggaaa cagcacaacc
   133381 tcgacctccg gaaagccatc gacaggcagg ggaggatgac tgcaatcgcc gggaagtacg
   133441 ccgggatgaa gtcaggggag tgccggaagg ccatcctcga ggacatgaaa aaacagcaga
   133501 tcctgacccg gcaggaaccc ctcgaacaga gggtgggggc gtgctggcgg tgcaagacgc
   133561 cgatcgagat catgagcgaa cggcagtggt tcgtaaaaat cgatcccgaa gccatcatga
   133621 aggccgcccg tgagatcagg tgggtcccgg aacacatgct cctgcgcatg gagaactggg
   133681 tcagtcagat ggaatgggac tggtgcatct cgcgccagcg catttttgca acccctatcc
   133741 cggtctggtt ctgcaacgcg tgcggggaga tgatcgtccc ggatgaagac cagctgcccg
   133801 tcgacccaac ggtcgacaag ccgtcccggc cgtgcccgcg ctgcgggtca acggactttt
   133861 ccggggagga ggatgtcctc gacacatgga tggactcgtc catttccgtc ctgaacgtca
   133921 cgggatggaa cggaaaggac gtctctcccc tcttcccggc ggaactgcga ccccaggggc
   133981 acgatatcat ccggacatgg gcattctaca cgatactccg ctccgttgca ctcacgggga
   134041 aacgcccgtg ggacacgata ctcatcaacg ggatggtgct cggggaagac gggtacaaga
   134101 tgagcaagag ccgcggcaac gtgatcacgc ccgaggagat cgtcgagaag cacggtgccg
   134161 atgcactccg ccagtgggca gcatcgggag cggcaacggg ttccgacatc atgttcaact
   134221 ggaacgatgt cattgctgcc tcccggttcc agacgaaact gtggaacatt gcccggttcg
   134281 tccacctcca gctccggcgc aggccctact cgcgggacgc cccgcccgtt gccctcgcgg
   134341 atcgctggct cctcgactgc ctggccggga ccgttgaaga ggttacggcc gcaatggatg
   134401 cataccagtt cgatcgtgcc ctcaagctca tacgggaatt tgcctgggac gtgcttgcag
   134461 accactacat cgagctcgtc aagggcaggc tgtacgcgga tgacccctcc cgggacggtg
   134521 catgccgggt cctcgagact gccattgata ccctctgcag gctgatggcc cccttcacgc
   134581 cgttctttgc cgaggagtgc tactcgtacc tcggaagggg cagcgtgcac gcacaggaat
   134641 ggcccggtct cctcccccgc gaccctgatg cccgcaggaa aggtgacatc ctcgtcaacg
   134701 tcgttgccga gctccggcgc tacaagcacg aacagggtct tgccctgaat gcccccatgg
   134761 gacgtgtcac catattctcg gcgccttttt cagacgattc caacgatgcc tcccggaccc
   134821 tgaacgcccc ggtcgaatgg cacacggaac ctccccgcct cgaaaaggtc ccgggagacg
   134881 tccagttcaa catggcggtg ataggtccgg cactccggaa ggatgcgggt gctttcatga
   134941 aagcggtgag ggcactgccg caggatctcc tcctgaaccc tcccgaaaag atcgatatcg
   135001 gcgggaagga gatccctgtt cccaaagact cgttttccgt ccagttcacg taccggctcg
   135061 ggggagagaa ggtcgatgtc agggtcgttg gcgacgtgat cgcaacgatc catgccagtc
   135121 cctgatcgct gccgcgacca gggagtgcac ctcgtgtgcc ggacgacccg catcgacaat
   135181 gaggaaccgt gacggttcct cttccgcgaa ccggaggtaa ttcttctgga cgcgttcgag
   135241 cagggttgct tcctcgaagt gctcgggaac tgcagccccc gccttgcgcc tgagggcttc
   135301 tgcaaccggg aggacgagga ggacggtgcg gtccggcggg atcgtccatc cgtcgtggac
   135361 cgcccgcaac catcccaggg ggtcggggat gatcccctcg agcgtgaccg actggtacgc
   135421 atagcggctg tcggtgtacc ggtcggagat aaccagccgc ccctccgcaa gtgcaggacg
   135481 gacgatcgat gagagatggc ttgcatggtc cgcggcaaag aggagagcct ctgtcacggg
   135541 gtctgccctt tcggcaattg ccctcctcac ctgcccgccg atccaggtgg ctccgggttc
   135601 ccgcgtgaac acgggggaga ggtcggagag cgagtcctca agggctgaaa gaagcgtgct
   135661 cttgccagtg ccatcgatcc cctcgagggt gatcaggacc atgtgcccct cctcacggca
   135721 tcgggcggga ttctgcccct gtggagagcg gttgaaacga ttgcgccgtc gtagccgagt
   135781 gctgcgaggg catcgaggtc ttcctcgccc gaaattccac cgccgcagag cagttccctg
   135841 ccatacgccc cgcgcaatct cccgaggagg gggagatccg ggccttttcc cgtcccgaca
   135901 gcaccgacgt ccagaacgat cgcccctgaa aaattccatg actctgcccg ggagaggaca
   135961 tccagcgggt cctgaccgga cgaaatgact ttcccgtccc ggatatcgac cgagaggaga
   136021 cccccggggt aaagggcaaa atccacttct gacgattcgg tcgaggcaat gtccgtaata
   136081 cgggggtggt ggagaaaatc agacgggccg gcggcaccgc ggtcgagcag gcaccgcgag
   136141 acctccctgc tgcacgagag aacctccgcg gtgttgtcgc ctgtccgcat gatcctgtcg
   136201 aggtcagcaa cgtagattgc cctgggcgaa acagccctga cataccctgc aggctcggcc
   136261 gtcggggaaa gtccccatgt caggggcatg tatgtccggc ggttcccgga agacccgtgc
   136321 accacaactc cgccttttaa gtccattgcc agaatcaaat ccatgcgaga gcgtaatcac
   136381 tattagatag caggatcatt aaatcctatg caattattgg tcagcccgag ggacatcgag
   136441 gaagcaaaac ggtctcttgc cgctgatatc atcgacgtga agaaaccctc cgaggggtca
   136501 ctgggtgcga attttccctg ggttatccgg agcatcagga aactctctcc aaaaccggtg
   136561 agtgcagcca taggggactt tgatttccgt ccgggcggag ctgcccttgc agcgtacggg
   136621 gcagcctgtg ccggtgctga ttacatcaag gtcgggctca tgttcgacgg tgcttcccgg
   136681 gcagaagagc tcatcagggc cgttgtccgg gccgtcaagg acgaattccc ggagaaaaag
   136741 gtcgtgattg ccagttattc ggactgggca cggcttggtt ccatctcacc ctctgatatg
   136801 gcaccgctgg ctgcacgggc cggcgccgac gtggccatgg tggataccgg gataaaggac
   136861 gggaggagca ccctcgagtt catgagcgag caggaactgc gtgatttctg caaattaaac
   136921 agggacaatg gtatcgggac ggccattgca ggatcgctca cgttcgatga tctccccgtc
   136981 atcaggaaga tctccccgga catcatcggc gtccgcggga tggtctgcgg gggcgaccgt
   137041 gattccggaa tcagggagga actcgtggaa aaactggccc ggatggtgca ttgaaccatg
   137101 ttttccgaga aactgaatgc tcccctcgca ctgacattcg atgatgtcct tctcgttccc
   137161 gcatcatcgc tcgttgagcc aaacgaggca gatatcagga cgcggttctc gcggaacatc
   137221 ccgatgaaca tccccctcgt cagcgcagcg atggacacgg tcacggagtc ggccatggcc
   137281 attgcgcttg cccgggaagg gggaatcggt gtcatccaca ggaacatgtc cgcagaacag
   137341 gaggtcgcag aggtccggcg ggtgaaggag tcagagcagc tcatcgagag gaaagtcctc
   137401 tcggtggacc cggagacgag tgttgccgag gtcgagcgcc tcatggtcga gcacgggata
   137461 ggcggtgtcc cggtcgtcga ggcgggaaag atcgtgggta tcgtcagccg gagagacgtg
   137521 cgggcgatcg ccacgcggcg ggggaacgag agtgtccggg caatcatgac aagggacccg
   137581 atcactgccc gggagaacat ttccatggaa caggcactcg agaccatgta taccaacaag
   137641 gtcgagcgcc tgcccgttgt cgattccgag ggtcacctga ttggcatcat cacgatgcag
   137701 gatgtcctcg agaagagaca gtatcccaat gccaccaggg attcgcagaa gcggctccgc
   137761 gtggcagcag cagtcggtcc gttcgacttc gaaagagccg tgcggcttga cgagtgcggt
   137821 gcagatgcac tcgttgtcga ctgtgcccac gggcacaacc agaacgtcgt gaagtccatc
   137881 cgggacatca aggggagcgt gaaggctgac gtgattgcag gaaacatcgc gacagcagct
   137941 gcagcagaag atctcgtgga cacggtcgac ggcctcaagg tcggcatcgg gcccgggtcc
   138001 atatgcacca cccggatcgt tgcaggcgtg ggcatacccc aggtgacagc gatcgcgagc
   138061 gtggcggatg tcatccggga gacaggggtc ccgctgattg cggacggtgg catcaggttc
   138121 agcggcgatg ttgcaaaggc aattgcggcg ggtgccgatt ccgttatgat tgggagcctc
   138181 tttgccggga ccgacgagtc cccgggccgc atcatcacga tgaagggacg gcggtacaag
   138241 cagtacaggg gaatggggtc cctcggcgtg atgagcgggg gcgtctccag cgacaggtac
   138301 ttccagaaaa aggagatagg aaagaccaag ttcgtgcccg aaggcgtgga gggagtgacc
   138361 ccttacgtcg ggagcgtatc cgaggtcgtc taccagcttg tcggcgggct gaaggccgcg
   138421 atggggtaca ccgggtccca tacgatcagt gacatgcacg aaaagacaag gttcgtcagg
   138481 ataactgccg cagggcacac cgagagtcac ccccacaata tcatgatcac ggacgaggcc
   138541 ccgaattacc gcctcaccga ttaatacctt tttttttcac cctgctgccg gtttctgggg
   138601 cgttaaacgg gagataatgc ccctgttcaa ccccactcgc cggctgtcgc gtaatccggg
   138661 accctttcag gaaaagaaga ttcccatgaa gattgcgaga ttgtgaacaa agaccaccat
   138721 gaagaacgca cagacagcca tgaggatgat ggccccggaa tattccttca tttcttccgc
   138781 acgcccggcc acgtagatga tgaagccggc aaaggcgcac tttactccga ggtggaggca
   138841 ggggttctgg acaatccatg ccatgacagg gttcatctcg aacccgccaa gacgaaggat
   138901 aatcgtcgtg aggaggacgt caagcacaag aagcccgccc agcaaggcga aaagggctcc
   138961 aatcatgatc tggtaggctt tctgcaccgg atagagtgtt ttcccggtat gtgtgaaaaa
   139021 tttttatatt cgattgaccg ggcaccccca tcctgctgta cctgtccacc ttcctctttg
   139081 atggttgaaa gaaggaattt cccccgccac aattatcggg gagccccccc tgatgctttt
   139141 ccgacctcca tgaaacgacg atacatttta tttatgagta ttactaacat aaagtaactg
   139201 atgcttgacc aggtcgagat cgccagaatc cttgatattc tcggtaatcg caaccggaga
   139261 cggatcatcg atctcttacg acagaagccc tgttttgtca cggagatatc cgacaggctg
   139321 atgctctctc cgaaagccgt tatcgagcat ctccagatca tggaaaggga ggagatcctc
   139381 tcgttccgga tggacgagag gcgccgcaag tactactacc tggccaatga cattgacgtg
   139441 atgatccggc ttctcaagcg tgaacaactc caaaccgcaa caagggatga atcaaacagg
   139501 ctccggtcag ccctcttcca gttgcgcagg atgatcgaat tgcgtgagga acttgcagaa
   139561 aaactgaaaa ataccgaaca ggcaatcgac gggcaaatca gggatataac gaaccttgca
   139621 caagctgctc ttgacaaccc cctccagaca gacatactca tcagcctggc ccactgtgac
   139681 ctgaccctgg acgacctgtg cgagctgaca gaagcaccgc gggatgccgt atccgataac
   139741 cttgagatac tcgggaagaa acatatgatt gaacaggccg gtgagacatt ccgcctgcgt
   139801 gatacccatg ccggattctg aaaacccgta cgacgaaatg cttaagaaaa tcgccaggat
   139861 ggtagaggaa ctcctgcgga acctgcccca ggaagagaac gcccgtatca tcggctgcac
   139921 gattatcacg aacggcgggt cgcctcactt cacgaggaac ccgaattccc ggagcgagga
   139981 gaatgatatc ccgatcgaga tcatcgactc ccccgacatg ctgtttgtca cggcaaggct
   140041 tccctccacc ctccacactg ctccctatgc cgacatcacg ggagaatcgc tccatatcgt
   140101 cgtcaacgag aggcgcatcc ccgtcccggt ctcctgccgg atcgatgtca tccacagctt
   140161 ctaccaggta aggcacggtg ttctcgatat catcctcaag aagaagaagg tccctccccg
   140221 gagtacaccg gcagaatcgg gataggacgg atgggtggtc cctgcactcc cggacggctt
   140281 tcttctcttt ttttcaggct ttgaaaggct ccgccttttt tcatccggca gacgtctgtc
   140341 ccgatgagaa tcacgtgatt ttcaccgttc ttttgcatgc ctgaagagat cctggtcacg
   140401 ccaccagcat ggacaggccg atggcaacca tgaggacggc aagcagtccc tggaggaacc
   140461 cgggggtgca cgtgtgggag aagcggacgc cgatccggga caggggcacc gttgtcacga
   140521 cgagcgcggc ccacgcgggg aggtacacgt aacccaggga caggggcggc aggccgggtg
   140581 cagacagccc atggataatg tacgctatca ccgctgcacc cgaggagaag acgaggcatg
   140641 ccgatgacgt cccgatggca ctgtgcaccg ggaaaccgaa gaggatgacg agcagcggaa
   140701 cgagcaggac accgccgccg atgccggcaa ggcccgagac tgtcccgatg aagaacccga
   140761 gtactgcaaa tgctggtcct gaaccgttct tccggttttc cggggatgac tggctggacc
   140821 aggccatcct gattgccatc gtaatgacca gaaccgcaaa gatggtccgc aacgtggttc
   140881 cgggaaggta agatgcgacc gttcccccga aaagacctcc caaaacggcg cctgccgcaa
   140941 gggggactgc tgctttccag tcgactgcct ctctcctgtg atggcctgca gtgccgctga
   141001 ccatcgtcgg aatgatgact gcaagagacg tcccgaaggc gaggcgggtc gcttccgtgt
   141061 cgccgattcc ccccgttgaa aagagccagt agaggacagg agtcatcaga aagcccccgc
   141121 caatcccgaa gagaccggat gcaaaaccgg ccgttccccc tgtcccgacg aggactgcgg
   141181 cagcaacgag cggttccatc ttttgttctc ccggtcttta tgagatctac cagtattttg
   141241 aaccggcagg tatatcacag gtacgtgaga tccatgggtc tttccgcact cctgatcatc
   141301 gacatgcaga acgatttcgt gagagaagga tcgccactcc gcgtggccgg tgccggggag
   141361 atcatccccc gcatccggga ggtcctcgat gccttccggg agcgccacct ccccgtgatc
   141421 catgtcctgc gggtccaccg gagtgacggg tccgacgtcg aggtcttccg cagggaactc
   141481 ttccgcaggc gggcattcgc tgtcaggggt tcgtgggggg cggcggtcat cgacgaactc
   141541 tcacccgcac ccggcgaata taccatcgag aagacccgga tgagcgcgtt caccgggacg
   141601 gatctcgacc tcctgctccg atccctcggg gtgacgcgcc tcttcgtgac cgggatccag
   141661 acccccaact gcgtccggac aaccgtcttt gatgcggcgg cctgcaacta cgaggtcttc
   141721 ctcgtcaccg atgcggttgc tgcccagagc gcggaggtcc atgccgcaaa cgtccgtgac
   141781 atggaaaaca tcgggacacg gatcatcagg gccgcggaag tgccccggat cctcgataca
   141841 cccgtcccga tcgacccgtg ataccaggcg cgagtttttt ccaaaaaaag gagtccgtgg
   141901 agtccccggc agggaggacc cggcagggcc ctatgccctg acgccggggc cggtcgcgac
   141961 ccacccggat atccggccac gctccccttc atgctcgcgg aactggtgga gcgagaccgt
   142021 gaggtcacgc gtgaacgcaa agtacccaat ctgggttgtc cggcagaggt tgagggccat
   142081 ctccatgagc ccccgcgggt cagggcggga ttcaccgagc cagatgtgga agatattccc
   142141 cccgtccacg atcgggaaga agacgtgctc gattgcgatc ctctcggcca tcgtgatgtt
   142201 tgcaccgggg gccacgtggg tcccgttcgt gtagtaaatg gggagatcgc gggtctttcc
   142261 aaggtccctc tgtgctttct ccaggtcacc cttgatcacc ctctttgcgt ggtccctgaa
   142321 ctcgctgttg aggaggtctg cgactgcaaa ccgctggccc gtggtctctg caggggtacg
   142381 ggcaagggca atcgtcattt tgtggcgttc cgagagctcc tttgcataga attccatctt
   142441 tgtcattgca aggacagcaa gcgagaatgc ctcgcgtgac tcgtgcatct gcgcaccggt
   142501 gtggtgctgc accatctcgt tgacaccgac cacgccaatc gtgtacacga ggccgtcgag
   142561 atccacggca acggctcccc gctcacccgt gtgcggatcc ctcgggcgct gcatggcaaa
   142621 cggcatcctg ccctgtgccc ggatggtctc aagccaccgc ctcttgatcc tgaagacctc
   142681 cacgcagacg tccatcagtg cccggagctc ggcaaagagc ttctcgttgt ctccccctgc
   142741 ccggtatgca gcccgcgggc agttgaggga aacgacctgc cacgacccca tggagaagtg
   142801 cttcccgtca cggaagtaga gcttgtcctc gaactggctg tcctggtcgg caatggccga
   142861 gaactggtag gcacagcact ggtaacacga tatgcccttc ccggcacccc ggtatgccgg
   142921 gatctggtta tcgtagtagg gcgttccaaa cttggaggcg agttcaaacg tgaggaggta
   142981 caggtcccgg taggtcggca ggtcaggatg cgcatcgttg aatgcctcgt cctcctgcat
   143041 gaagtccggc tcgatgctga tctcgggctt ggggaaggag aacggctttc cccatgcgtc
   143101 cccctcgagc atgacctcca ttaatgcctt gaagaggagg cgtacctccc tctcgaactc
   143161 cccgtacgtc ctgcgcggtc ccctcgtccc gtcccagacc atcccgcggt acacgcacgg
   143221 cttgtccttc cagagggagg ggactcccgg gctgagctgg acggacgaga agacgagctg
   143281 gcctccccgg gcaaccatca tctgcgtcat ctcgtacacg aacatctgca tgagctgctt
   143341 gatctcgtcg tacgccatgc cctcgaagta cggtgcaagg aacgtgagga agttgtagta
   143401 tccctggccc cctgcaaagt tcgtctgtgc actcccgagt gccttgacag cgtggaggac
   143461 tgcgacctct gcccgctttg caggccccgc gaccgatgcc ttcgtgccgt tcccgtcagg
   143521 catcaggccg tagtagaaga agtagcggag gtcccagtcc tggcaaaacg ggcgtgtccc
   143581 gaagtactcg aggtcgtgga tgtggatgtt gcccgaaagg tggtggtccg cgaggtgggg
   143641 gggaagctgg aggaggtact gttccttgct gatcttgtct gccttcttct tgtgcgaggt
   143701 ctccgcgttc tcctggaggt ttgcgttgtc cctcgcttcg aaaccgcgtc ccacgtcgat
   143761 ctggtgggcg tcgtacacgg gtgtccccac gcgtgtgcag acgttccggt actggaccat
   143821 ccccttctcg agcagcgtga tattgacgat ctccctgatg agcggcccgc tcaaggtctg
   143881 gaggttcatc gacttgatcc tctcttccac gagccgtgct atctcccggg cggtctcctc
   143941 gcttgcgctc tcgtagccat agaacgtgga gacgagtttt gtctcctcga cgatctggcg
   144001 gacgatccgc tcccggtccc attccaggat gtgcccgtcc gtcgtccgga cggggggcat
   144061 cggggctaca aagaccccgt caagagtcga ctgcctcgtg tcgcgtctcg gcatcagtga
   144121 ccctcgagga acgagagaac ggtatccgtg cgcaggcctg atgcggcgaa catgtcaccg
   144181 gacacgagga acctgtcccc gctccggagg acgggagcct cgcgaacgaa gacaccgttg
   144241 atgcggaggt ctgccagcgc ctcggccgtg gagaggtccc gctcg
//
LOCUS       DAOOJU010000002       117108 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_157_length_117108_cov_16.276097, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000002 DAOOJU010000000
VERSION     DAOOJU010000002.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 117108)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 117108)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..117108
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_157_length_117108_cov_16.276097"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(172..1050)
                     /gene="frhB"
                     /locus_tag="PK679_00780"
     CDS             complement(172..1050)
                     /gene="frhB"
                     /locus_tag="PK679_00780"
                     /EC_number="1.12.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420 hydrogenase subunit beta"
                     /protein_id="HPC54531.1"
                     /translation="MAGELGKYKLCVSARSTDKAILKKAQDGGIVTQLFKFALEEGII
                     DGAIVAGPGDEPWRPRPFIATTVEELMTAGGTKYNISPQVSWIKEATRSYGLDKIGIV
                     GTPCQMQAVRKGQLYPVGWRDVDDKIKLAIGIFCMENFSYQSIRQLVEDHAAMKMEAV
                     KKMEIGKGKFWVYGQRGQVVQLPLKVTHKYEQPACHVCLDYVANLADVSTGSVGSPDG
                     WSTVFVRTRNGDDIWSKAIAAGCFETKPIEQVKPGLELVTKLATEKITKNQKTVEERA
                     KFGVNKALRNPYLGPK"
     gene            complement(1061..1942)
                     /gene="frhG"
                     /locus_tag="PK679_00785"
     CDS             complement(1061..1942)
                     /gene="frhG"
                     /locus_tag="PK679_00785"
                     /EC_number="1.12.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420 hydrogenase subunit gamma"
                     /protein_id="HPC54532.1"
                     /translation="MGLLSKIFGKKSSSEKPEAKPAAAAGVEKKAETIKKEEKPVADK
                     ITVGHVHMSGCTGCLVSLADNYGGLLTILDKYADLVYGLTLADVRHIPKMDVALVEGS
                     VCIQDKLSVQEIKETREKAAVVVAVGGCACYGNITRFSRGGQPNQPQHESYLPIGDLI
                     KVDVYIPGCAPCPQLIRNVCVMAYLLLKGNKDQQELAKKYLAPLMQLAERGTEACGCD
                     LMIDVVNQGLCMGCGSCAAACPVRAITHEYGKPNVNREMCIKCGACYAQCPRSFFNFD
                     VVPEFEAIMDAIGAALK"
     gene            complement(1848..2402)
                     /gene="frhD"
                     /locus_tag="PK679_00790"
     CDS             complement(1848..2402)
                     /gene="frhD"
                     /locus_tag="PK679_00790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-reducing hydrogenase, FrhD
                     protein"
                     /protein_id="HPC54533.1"
                     /translation="MLYPEIVIAGCGNPLFADDGFGPAVIEELQRLDLPDNVKAVDAG
                     LGGPHFIFTLLDPAVTRKLIIVDTADFGGKPGQLARFSVDDLPPGSYRDAHSWDLTEP
                     LHRLKHKVDITVIGCQPRRVSAPEFEIGLSDEVMAAIPRAVREVLALIGVDYGTTLEN
                     LRKEELQREAGGKTCGSSWCGEEG"
     gene            complement(2413..3780)
                     /gene="frhA"
                     /locus_tag="PK679_00795"
     CDS             complement(2413..3780)
                     /gene="frhA"
                     /locus_tag="PK679_00795"
                     /EC_number="1.12.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420 hydrogenase subunit alpha"
                     /protein_id="HPC54534.1"
                     /translation="MSKIVEISPTTRHEGHSKLVLKVDDAGIVERGDWLSITPVRGVE
                     KLAIGKTMDQVPKIASRVCGICPIAHTLAGIESMEGSIRCEIPKDAKLLRIILQAANR
                     LHSIALHNILILPDFYLPGTDTKINPFSPQEPVRSVAKRIQRLREIGQTIGEIAGGEA
                     VHPSNPRVGGMYKACTKQAVTKMYDLAKEGLVLAHEQMEFMLAIINNMKKRDWVEVGG
                     KQIPLPKTLGYHNQGVMAAHPMYASTNLDENPGWDPNRWTDVRPWDWYMGEGEVSLAD
                     PSYPIGGTSPVGTKVNPQMEACTGVPLYDGAPVEVGPRARLVTFKNFDEKGTWGQHIA
                     RQLEYTDCLYTILKALDEYNPSGKVIADHIPQGDGSLGWAANEAPRGTDVHLAKVKDG
                     RVLYYEMLVPTTWNFPTCSRALTGAPWQVAEMIVRGYDPCVSCATHMIVIDEDRKVIA
                     QKLIQ"
     gene            complement(4178..5119)
                     /gene="mptA"
                     /locus_tag="PK679_00800"
     CDS             complement(4178..5119)
                     /gene="mptA"
                     /locus_tag="PK679_00800"
                     /EC_number="3.5.4.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase MptA"
                     /protein_id="HPC54535.1"
                     /translation="MPDIQSTLPDVRINLTRVGVKNVKKLVEVSRPEKRPVIFISNFD
                     VFVDLPGSLKGANLSRNFEVIDEVLQQAIDGEVKEIENLCSVVARKLLDRHEYADRTE
                     VLMNSQFMVKRETPISRTHCHEVVKVHARAVARRTFREPIVRKSIGAEVTGMTACPCA
                     QDIMKERAISVLQGLGIPDEKIELFLQEVPMATHNQRGRGFLCIEIDDDQHVKLEKII
                     TILKESMSSSIFELLKRSDESYVVLNAHKNPRFVEDCVREIAKKVIHEFHDLPGDSLV
                     TIKQTNEESIHQHDAYAERQATMAELFVEMNGESSDT"
     gene            5243..6244
                     /gene="ilvC"
                     /locus_tag="PK679_00805"
     CDS             5243..6244
                     /gene="ilvC"
                     /locus_tag="PK679_00805"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HPC54536.1"
                     /translation="MMEKYYDSDADLGVLSGKKIAVIGYGSQGRGQALNLRDSGLDVV
                     IGLRPGRSWQAATADGFKVFPVPEAVKMAQVIQILVPDELQGALYQAEIRPHLSGKKC
                     LMFSHGFNIHFGQIVPPPDVDVVMVAPKGPGRMVRKMYEEGKGVPALIAVHQNYTGQA
                     QQIALAYAKGIGATRAVVLETTFREETETDLFGEQAVLCGGITSLIKAGFETLVDAGY
                     APEMAYLEVLHETKLIVDLIYEGGFTRMRNSISNTAQYGDLTRGPRVIGPETYIAMQE
                     ILREIQTGEFAKEWMLENMVNRPVFNALTKADEEHLIEQVGKEVRAMMPQFQNTEKT"
     gene            complement(6279..8351)
                     /gene="purL"
                     /locus_tag="PK679_00810"
     CDS             complement(6279..8351)
                     /gene="purL"
                     /locus_tag="PK679_00810"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HPC54537.1"
                     /translation="MLSARDLEQIRNRLGREPTDVELACFENLWSEHCSYRSTRALLK
                     TLPTTGPGVLLGPGDDAAIVRFNDRTALAVGMESHNHPSYVDPHDGAATGVGGIVRDV
                     LSMGARPIALMDPLYFGPLDREKNRYLFEHVVAGIGGYGNCIGVPVVRGDLCFDPDFS
                     GNPLVNVVCIGTVAPDSFLTARVKKPGNRLVLVGSSTGRDGLGGASFASRDLSEDAEA
                     SDRPSVQIGDPYTEKLLIEAVLEMAATGKVLSCRDLGAAGLAGASSEMCSTFGGLIWA
                     EKVHQREKDMHPVEIMLAESQERMLLEVEPDDVPLMGQIAEKYDLSWSEVGEVIDEPV
                     YRVTFHGRVVCDIPIDFLVTKAPPCTWDSRPYNASKPFSRPSEDIAGLARKVLSHPEV
                     AFKNWVFEQYDHDVQLRTVSLGPDAAVLRLDGEALALSCGCNPRHIYLKPYEGTANAV
                     LENASNLACVGASPLCIVNCLNFASPVHPEVYWQLSECVRGLGDAARNLATPVVGGNV
                     SLYNESDEHDTRIKPTPSIGMLGKGPLFTPARPGEGWGLALLGEPGAHFGGSVLDAVT
                     GCGGDAPPLGSARFLPLVRERVCTTRDIAVTDISQGGLLGALVTFSPGCTVTLDCDLL
                     PGLFSETYGRFLLAFRDEKDIRDLPCRVIGTLGGERLEVTGKTGKLVLDAGEVAEALS
                     SLTRCMQL"
     gene            8441..9058
                     /locus_tag="PK679_00815"
     CDS             8441..9058
                     /locus_tag="PK679_00815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 subunit beta"
                     /protein_id="HPC54538.1"
                     /translation="MVDPYETLLKKAYSHVTEPTEARERFSVPEARSYIEGKTTVLEN
                     FAEIADTLRRDRDHLMKFLLGELGTAGKIDGSRAIFNGKFEPGLINSLIKSYTEDYVI
                     CSECGKPDTRLVKDDRVLLLRCDACGGHRPVRKRKARTEPVVNEVTEGATLDVEVQSV
                     SRRGDGVVRMGKYILYIPGGKPGQKVKVRITRVSGSIVFTERLPS"
     gene            complement(9141..9431)
                     /locus_tag="PK679_00820"
     CDS             complement(9141..9431)
                     /locus_tag="PK679_00820"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit L"
                     /protein_id="HPC54539.1"
                     /translation="MNIKILELTKDKVKLLIQGEGHTFMNVLTEEILTDPDVDVAKYL
                     IKFQFSDPELLVTTNGKKDPLQAITEACQRISRTCDDLLGSLNASAKKKSKK"
     gene            complement(9513..10232)
                     /locus_tag="PK679_00825"
     CDS             complement(9513..10232)
                     /locus_tag="PK679_00825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC54540.1"
                     /translation="MKIVLLGTGDAVGTPRVGCSCPQCSHARQTGRERLRTSLLVSES
                     GHNILVDTGPDLRRQLLENGSPRIDAVLWTHGHYDHFMGFGEFYRVQKMPTVFAPPPV
                     MDYCGKIFSFLDFPPVRVGEYEPFVIHGIEWTFLPVCHPPAYTCGLLISAGDVRIGYT
                     SDTNRNIPDRTREALTGVDLLLVDALLPGRLHVPKHMNYEEACELAEDLHAGDFRCVH
                     LSHLVPLDLPRLGRDGEEFVF"
     gene            complement(10235..11512)
                     /locus_tag="PK679_00830"
     CDS             complement(10235..11512)
                     /locus_tag="PK679_00830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC54541.1"
                     /translation="MPVDDEILKLMEIVLTAEIFNTRPDLDANDLTPECRIIFGINGS
                     VDVRRPVHVSEGMIRRGLGITDACRKLQETPVITCEEFGQRIRVTTLEPAARWFLKKG
                     GLPIIQKNPALAYFFRDFESTNVSYEDVRANNPPVEDTRAFLQSRIATLLAGDERLKG
                     ALDLVIISAPEEVEQDFGDLVCTPAQETVIRKIQVARTHRDLLRKHRIHEVGKLLFVG
                     PPGTGKTSLALALSRKLHLPVIEVRLSMITSQYLGETSKNIDRIFELAKSLSPCILFI
                     DEFDFVAKSRVTDDHGAMKRAVNSLLKNIDQVSLIRHGVLLIGATNHPQLLDGAAWRR
                     FDEVVEFGLPDRDMRLAILRKIAAGIRCSCDFPDLADATDGFSGADLRIMVKEAILSA
                     LMDRREEIGPADIERGIAAVKNRNAIRSQNWLA"
     gene            complement(11557..12432)
                     /gene="map"
                     /locus_tag="PK679_00835"
     CDS             complement(11557..12432)
                     /gene="map"
                     /locus_tag="PK679_00835"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II methionyl aminopeptidase"
                     /protein_id="HPC54542.1"
                     /translation="MKDEEIDLYIEAGKIAARILAQGAREIRVGVPLLSLVEKVEGMV
                     IDAGAGLAFPLNVSRNEDAAHDTASRGDQRVFEPGDVVKIDLGVHLDGYIADCATTVD
                     LGDHEGLIAASREGLERALECVRPGVTTGALGKAIQKAIESRGFRPVVNLTGHGLARY
                     MIHTPPNIPNVGFPGGAILKEGLVFAIEPFATTGSGQVSEKPRAEIFQQVAVRPVRPP
                     AARRILDEVRERRGMPFSRRWLSDPRPDIPLASLARDGVLRRYPVLADVAGSLVSQAE
                     HTLIVTGDGCIVTTR"
     gene            complement(12442..13569)
                     /locus_tag="PK679_00840"
     CDS             complement(12442..13569)
                     /locus_tag="PK679_00840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HPC54543.1"
                     /translation="MDALDRALKEGGFGAYVAFGTSGDANILYLTRFSTTDPILYIRK
                     PGERGLIVVSQMECERAAKEATTAVISRADAGFFDVAKEESNPWRVLARVIGRQVEGP
                     LLVPPHLPYALGSELARERKVAIDGGVLARMREVKKAQEIRCIRDVQHVCDIAMDRAL
                     RMIRKAKARKGLLFQGAIPLTSSFVRSAIHQVFVQNGCIPSDTIVACGEETAMPHRRG
                     DGQLREGEPIVIDFFPRHEKTGYFSDMTRTVCRGEAPPEIAEMFGAVRDAQDLAAKLI
                     KPGISGAGVYQAIVDFFRDAGYESGSRGFIHSLGHGVGLEVHERPGLGPSGEELIENS
                     VVTNEPGLYYPGTGGVRLENTGVVKRGGFSSFTRFKRELVL"
     gene            13632..13859
                     /locus_tag="PK679_00845"
     CDS             13632..13859
                     /locus_tag="PK679_00845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54544.1"
                     /translation="MDAATREQFKWKFYKLAIILNGVVLMAALGVVVFFKAPGTLNIP
                     LAALFFVLAAGLSLFFRRKYRLTKEWLDAQS"
     gene            13893..14171
                     /locus_tag="PK679_00850"
                     /pseudo
     CDS             13893..14171
                     /locus_tag="PK679_00850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619176.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14271..14343
                     /locus_tag="PK679_00855"
     tRNA            14271..14343
                     /locus_tag="PK679_00855"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14304..14306,aa:Asn,seq:gtt)
     gene            14357..14431
                     /locus_tag="PK679_00860"
     tRNA            14357..14431
                     /locus_tag="PK679_00860"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14392..14394,aa:Ile,seq:cat)
     gene            14538..15566
                     /locus_tag="PK679_00865"
     CDS             14538..15566
                     /locus_tag="PK679_00865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54545.1"
                     /translation="MKCPVCGSDCIEDAGVVLGRLPDLFSPCDQCSYRVLDKNAPLSD
                     GKYTPPCRCGKRFIDEVYAHLYVILVEEGVFSGKEPLRAVGSPLIHPGVFTAAPPFLP
                     EDSLVLLSPRVTVPVAERFVAEVPEIRGVVRSGDFVPGAVDPTLEKSPRTYDLLAGCD
                     VRAGIFPTSAGPLVIYTQQSLIHIEFPRPRNPKIESVERRLKEGLPAVFVDACAGNGT
                     LGLCAALHGVGKVILNDAWYAAAYWSAQNIHVNRKALKVTGVTTTLSYDEMKARQVSR
                     EPVLVAETEGEQDVSVFFGDYRELWKVLPPGPVCAVLDLFDKSDMEANRRIMKEWRDR
                     VPGEVFIP"
     gene            15580..15893
                     /gene="ffs"
                     /locus_tag="PK679_00870"
     ncRNA           15580..15893
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PK679_00870"
                     /product="signal recognition particle sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01857"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="archaeal-type; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01857"
     gene            15918..16868
                     /locus_tag="PK679_00875"
     CDS             15918..16868
                     /locus_tag="PK679_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HPC54546.1"
                     /translation="MAKVTIVGATGNVGTFCAHTIGHIPYVDEILLHGREGRENLLAG
                     ITRDLSDSFAAAGKAVNLSWTTDLADARNSDIVVCTAGVARKPGQDRLDLALENARIV
                     SKTAEGIGIHAPDAMILMVTNPVDVMTSVALRYSHMAPHHVFGLGTHLDSMRLKSLIA
                     RHFRVHVSEVHTRIIGEHGESMVPLWSATTIGGIQISNLPAFIGLPVNDIMGVVRSSG
                     EEIIRNKGATVYGPGEAIATLVRTILGNENRILTVSAYIRSEVHDIGDVCIGVPARMN
                     RQGVFPVPIKISEDEVARFRESVEKIRTITAAVLEKLKTQ"
     gene            complement(16918..17175)
                     /locus_tag="PK679_00880"
     CDS             complement(16918..17175)
                     /locus_tag="PK679_00880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 1-beta"
                     /protein_id="HPC54547.1"
                     /translation="MGTVAVILKVMPESPDVDLVKLKDRIKNEVPAVRDIREEPIGFG
                     LKALIVAALVNDAAGESDAVEAAIQKIPGVERAEITEVTLT"
     gene            complement(17179..17340)
                     /locus_tag="PK679_00885"
     CDS             complement(17179..17340)
                     /locus_tag="PK679_00885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc finger domain-containing protein"
                     /protein_id="HPC54548.1"
                     /translation="MPVRKCTSCNSPLAERGATEFGCPKCGYEIRRCFRCREQSIPYV
                     CPKCGFTGP"
     gene            complement(17385..17972)
                     /locus_tag="PK679_00890"
     CDS             complement(17385..17972)
                     /locus_tag="PK679_00890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridylate kinase"
                     /protein_id="HPC54549.1"
                     /translation="MISPPLVLKIGGSLFSRAEGICSLLARKERPVLVVPGGGPFAQA
                     VRETGAVGTEAHWMAVSAMEQYGWYLSRSGIPVTEELAMPETPRILLPYSILRSRDPL
                     PHSWDVTSDTIAAWCAHILGVPLVLLKSVDGIRSEGVMQQAIRSPVRTDDVDPCFLGF
                     VLDHGIPAMVISGLHPERLAAVLDGVATTGTTIGF"
     gene            18043..19710
                     /locus_tag="PK679_00895"
     CDS             18043..19710
                     /locus_tag="PK679_00895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="HPC54550.1"
                     /translation="MHWCRLFLALALVSHATGIALVEFCPDPYLPEDRDEYFCLGGSG
                     PLDGVMVSDGEGSVRFPAGAVLAGRCVVARDAGAYRMSHGEYPDYEWDGTTAEVPDMI
                     RTGRFQLANTRDEITLYRDRVPLQSVEWPGMVSTRQGQVHYCQNGTWDPRILMLGQSQ
                     FPEATFQDADGLAFVSPDCSREVFLSLARGARTEILVAVYEFTSPVLAGALVEAAGRG
                     VNVTVLLEGGPVGGIPKEERWVISRLEDAGIPVYTMSGTPDVHAPYRYMHAKYMVIDR
                     SSVLVTSENFKESGFPEREKRGNRGFGVVVTHPGLAEYFLSVFSHDAGGRFSIRAKTG
                     EGPEEMPSQDAYMPSFEPCRFSGATVTPVIAPDTSSLVRRLVQGAERSVDIEMAYITN
                     ESGSMLNPFLTDAVDAARRGVRVRVLLDSYYYNVEGESDNDEMVATINRIATAEGLPL
                     EARCADIGPGKVEKIHNKGAIIDGRKVLVSSINWNTNSPVNNREAALIVEHPGVGAYF
                     SSVFESDWNRAGQEGMAAQGPDVIKLVAAVLVVAAIIILFLYRKRGR"
     gene            complement(19726..20046)
                     /locus_tag="PK679_00900"
     CDS             complement(19726..20046)
                     /locus_tag="PK679_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC54551.1"
                     /translation="MKSHDCDIMFCDTMARRILPCLRAEMVCRLVQQRGISQSNAARR
                     LGVSRAAVSQYMKKKRGGTFFKLSPDMDILLDRWAEAVAGNGGTITLCDLCRCIRERS
                     PDFH"
     gene            complement(20043..20264)
                     /locus_tag="PK679_00905"
     CDS             complement(20043..20264)
                     /locus_tag="PK679_00905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC54552.1"
                     /translation="MGHLPPSSLIVLHILDDNGAMTHKEIVKKSGLAPRTVRYALKKL
                     KEQNLIAEKFNFEDARQVIYLSRPRAVTA"
     gene            20352..20729
                     /locus_tag="PK679_00910"
     CDS             20352..20729
                     /locus_tag="PK679_00910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54553.1"
                     /translation="MILVRQEKIALVLILVVIAAVAIATFALESAGKGAFARQMGPDS
                     REGDLVLLEGSVEEARMTATGGHQILRVEGVRVFVPSSAVRSGWPRVGDEIRVYGTVQ
                     TYRGEREVLVHSAGDITAVAPHS"
     gene            20870..21499
                     /locus_tag="PK679_00915"
     CDS             20870..21499
                     /locus_tag="PK679_00915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54554.1"
                     /translation="MEQEQRKFTGEGGHRIWILAVLGLVCIGLEVVVHLTLRTAVGYT
                     HIFYILLVLSALWYHHKALFIAGGLVCATLATSLFVGDLTWATILRAAMFLVITWIVA
                     TISDERDRARRMLQEQKEEIEKKHYALVGYISEAALRMKNPLEMLRDNLTSMRVQLDQ
                     GPDIEELKMMLSVQITHLEQIIGNFRELNREIVEERDEIPEAFREFLTR"
     gene            21506..22102
                     /locus_tag="PK679_00920"
     CDS             21506..22102
                     /locus_tag="PK679_00920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54555.1"
                     /translation="METQFDIGRLGQEKLFLVLSSAERLRQNNIRVIKTLIGRGYRVV
                     VITTNQPSAILKKHYAAEGIDMGKVTFIDAITKYAIGRIPEGETDTKFVNSPSNLTDL
                     GIAITEVLNPASGEKTCLLFDSISTMLIYLPSIHISKFIHFVTSKLRLLDVPGIFLAV
                     EKGIDPLLLTQLTTYVDDVIDMDKPPGLLGPDGKSPGT"
     gene            complement(22118..22627)
                     /locus_tag="PK679_00925"
     CDS             complement(22118..22627)
                     /locus_tag="PK679_00925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase-like protein"
                     /protein_id="HPC54556.1"
                     /translation="MVEITVMVLAFALVTAILALLILLLAYFRARERIDERAHTLFEE
                     WRSVSLEREARERAELLCREWVAAQETRIRRDAVERSEAVVRGRVTEHLIPFFPSFPY
                     NPRDARFLGSPVDFVVFSGLSAGSLDEIVFVEVKSGRSASLSSRERMVRACVEEGKVR
                     YHIMKTGGA"
     gene            complement(22694..23212)
                     /locus_tag="PK679_00930"
     CDS             complement(22694..23212)
                     /locus_tag="PK679_00930"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC54557.1"
                     /translation="MKIEAEEAMRRKRVRGLVGLLKSPYLDDRWKAAEKLGVIGDGSA
                     VPALIEALSDPFVEVSWIAAKSLGEIGDGRAFEPLIQALRSPEKWLRIGAAIGLGRLG
                     DRRAVPALIEALKDEKALVRKHAAWALGVLGDPSAAEPLRALVNDPDRRVREEVLLAL
                     KKLSPPGEGNSP"
     gene            complement(23403..24224)
                     /gene="nadC"
                     /locus_tag="PK679_00935"
     CDS             complement(23403..24224)
                     /gene="nadC"
                     /locus_tag="PK679_00935"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0019363 - pyridine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HPC54558.1"
                     /translation="MLLSFLAEDAPAGDITSGSVLSGERCRGRIVAREGGVIAGLEEA
                     EALFLFCDVIFRPLVRDGDRVGPDSVLAEVEGLAEAVLLVERTALNIMGRMSGIATMT
                     RSLQDVLDQKLPGARIASTRKTCPGLRVLDKKAVILGGGDPHRLTLSDGILIKDNHLA
                     IVPLETAIERARAHSCYRKIEVEVESPEVALRAARAGADILLLDNMEPPVVRETLRVL
                     MDSQLPRLPLIEVSGRINEDNIADYAIRGVSVISIGALTHSPKSLDIGLDLDAIV"
     gene            complement(24251..25156)
                     /gene="nadA"
                     /locus_tag="PK679_00940"
     CDS             complement(24251..25156)
                     /gene="nadA"
                     /locus_tag="PK679_00940"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HPC54559.1"
                     /translation="MTIEERIRALKEEKNALVLAHNYQRPGIQDLADFVGDSLELARM
                     AEGTKKPVIVFCGVLFMAETAKILNPERKVLIPVRDAKCPLADQLTPAMLARARAEHP
                     GAAVVLYINSTAECKALADIVCTSANAVDVVRSLDATEVIVAPDANLAAYVQSRVLEK
                     RVIAIPPAGHCYVHQCFSTQDVVSARDRGDTVICHPECRPEIQEMADLVASTGGMVRA
                     LRGQQPGRRWTILTEREMAYRLRTLYPDQEVHVRDDAVCRDMKKITTRDLLLSLEREQ
                     YEVILPQETMEKARRAIRRMLEAGQ"
     gene            complement(25153..25911)
                     /gene="nadX"
                     /locus_tag="PK679_00945"
     CDS             complement(25153..25911)
                     /gene="nadX"
                     /locus_tag="PK679_00945"
                     /EC_number="1.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate dehydrogenase"
                     /protein_id="HPC54560.1"
                     /translation="MIRIGLLGCGNIGHIIAKNRENCQILALYDQVFPRAQELADISG
                     GTAYSDFDSFISADFDYVVEAASVRAARQYGQRVLAEGKHLILLSVGALADPVFLSGL
                     IATARQSGRRIFIPSGAVTGLDNLKVGQISPVRRLLLRTTKSPESLGIQATDRQLVFR
                     GKAHECIKEFPRNVNVSVALSLAAGRDADVELYADPSVTRNIHEIEAEGDFGEIYIRV
                     SNVPSPDNPATSYLAALSILTLLRNLDSPLVVGT"
     gene            26172..27353
                     /locus_tag="PK679_00950"
     CDS             26172..27353
                     /locus_tag="PK679_00950"
                     /EC_number="2.8.4.5"
                     /inference="COORDINATES: protein motif:HMM:TIGR00089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase"
                     /protein_id="HPC54561.1"
                     /translation="MRTYGCTYNEGDSWKLAEILKARGCILVSDPLLADAIVINTCIV
                     VGKTERKILHELRQHAGRPLYVTGCMPLVQADAIRNVCDPVIIHPDDIHAAYAELKTV
                     PQGSVGVVQACRGCLGSCSYCVTHLARGKLVSRSLEDVTQEAARLVAAGAVELRLTGQ
                     DLSAWGRDTGQSPADLLRSLDALCGRFMIRAGMMNPATLFPVMDEVAEAFRLPKIFAA
                     LHLPIQSGAEKVLSRMRRGYTQEQVVSIVERFEREVPALSLTTDIICGYPGETGDDFS
                     ETLALLQRIRPDRVIVTRYSPRPGTRAWHEKDMPDRIKKERSRTLRVCAEEIARQKNA
                     RWKGRVLPVMITEHVRPGTSLGRTREYRAVVLQGSHEPGSVLSVRILEDRTYYFTGEP
                     V"
     gene            27511..28047
                     /locus_tag="PK679_00955"
     CDS             27511..28047
                     /locus_tag="PK679_00955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54562.1"
                     /translation="MSGKDEIEKGYTKLLGKIEEYNGKIEELSEEVRSRDSALMERMG
                     ELTAPLIGKIGLNMLKRGKQDTKGELYDTSFYKEKMIVLGRTDPVPHRPDDPGKKVDD
                     QFCVLGEDGRFYELMYSTDGVVVDSYRNPLSAQDALKLYGYDIMVMLYRAMRDYLQGQ
                     KELLDALEKTIAFITQGK"
     gene            complement(28060..28518)
                     /locus_tag="PK679_00960"
     CDS             complement(28060..28518)
                     /locus_tag="PK679_00960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54563.1"
                     /translation="MKRDLLIVLVLGLFACVALYFLVDIYASLIAAVLVIALAMSLFI
                     MQDSVMKPNIFVFIEENAKGIRVRNRGNAKALSVRVSLEPQDLHFDLPVLGEDEASTF
                     PVPPVTDKVKVNVSYRNEEGEAFSKTFFLRPGDIEDEDLLKPLFPLFGWK"
     gene            complement(28561..28634)
                     /locus_tag="PK679_00965"
     tRNA            complement(28561..28634)
                     /locus_tag="PK679_00965"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28598..28600),aa:Ile,seq:gat)
     gene            28770..30551
                     /gene="iorA"
                     /locus_tag="PK679_00970"
     CDS             28770..30551
                     /gene="iorA"
                     /locus_tag="PK679_00970"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043805 - indolepyruvate ferredoxin
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HPC54564.1"
                     /translation="MKTQYLLGNEAIAHGCLEAPVDFVTGYPGTPSSEVVDILRAVPD
                     RGYYIEWSVNEKVAFENALSAAWCGLRALCTMKHVGLNVAADPLMTSAYTGVTGGLVV
                     MSADDPFAHSSQNEQDSRCYALFSRLPCLDPSGIQEAHDMVRDAFALSEQFSLPVIFR
                     PTTRVCHSKGDTLIGEPVRNTRKGEFHKDPRQYVVIPAHTRILHKKLNEKQPALKKAL
                     VEKGYNTAVIRGRRAVVASGIAAAYVQEILPDDVSFIKIGAYPIDEEWLAAQVSRHEK
                     VLVVEELHPVVEEAVRQVAGTIPVSGKKNGVVPYEGELSTASVAAILKSFGINPGEEY
                     PATSPVADLPPRPPILCAGCMHRPVFYAMRRVFRDGVYPSDIGCYTLGLQLGAVDTTI
                     CMGAAVTVASGIAHAGDSRDIVATIGDSTFLHSGIPGLLNAVYNGARMILIILDNRIT
                     AMTGHQPNPCSGVTACGGPSPQVSLEALCRACGVSWVETVDPYDLVSLMATLRAAKDQ
                     PGVKVVIARQPCVIMARRANLRRGRFEVDPATCTACGVCIGFGCPAIEKRDDKAFITD
                     LCSGCGVCAQICPAGAIRKETRTEGKR"
     gene            30548..31153
                     /locus_tag="PK679_00975"
     CDS             30548..31153
                     /locus_tag="PK679_00975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HPC54565.1"
                     /translation="MSTSFDVLMVGIGGQGIILASNILGEACLAEGRSVKGAETHGMA
                     QRGGSVEGHIRIDGKFGPLIPPGSARVIIAFDMLEALRYAHFLAPGGMIVSNSHFVIP
                     TSVYMQGVPVPDEKSLRERLSAWPLCLVDADGIAAEAGSFLSQNVVMIGAASWFLPLK
                     PASLLGAIERLVPQKTVEINRKAFELGRAAGEKCRTERQGA"
     gene            31126..31920
                     /locus_tag="PK679_00980"
     CDS             31126..31920
                     /locus_tag="PK679_00980"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HPC54566.1"
                     /translation="MQDGETRSVKVRDTGPFFPDTIYQGDALALLPEIPAGSVDLIVT
                     DPPFAIDFRAKRTNYNRTGSRVLDGYCEVAPDEYGDFTNRWMEEAFRVLSPTGSLYVF
                     SGWNRLKEVLCGLDRAGFHTINHLIWKFQFGVFTRRRYVTSHYHILFAVKDPLRYTFN
                     KQDHYPEDVWFIRREYWKGKKKTATKLPRELVSRIIAYSSNPGDLVLDPFIGSGTVAV
                     VAREMGRHFLGFEVSGEYYAFALERLREEGMHTGLTSERGDAEGEN"
     gene            complement(31902..31985)
                     /locus_tag="PK679_00985"
     tRNA            complement(31902..31985)
                     /locus_tag="PK679_00985"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31951..31953),aa:Ser,seq:gga)
     gene            complement(32117..33031)
                     /locus_tag="PK679_00990"
     CDS             complement(32117..33031)
                     /locus_tag="PK679_00990"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided pseudouridylation complex
                     pseudouridine synthase subunit Cbf5"
                     /protein_id="HPC54567.1"
                     /translation="MVGNEEPVPVPRGGLIVIDKPRGPSSHQVTAWVGDILGQNVGHA
                     GTLDPGVSGVLVVMVGRAVRLAPVLLSHDKEYVALVRFHGNPGEEAIRKACSEFCGRI
                     YQRPPRRSSVARNLRIRTVQSLDLLELDGRLAVLRICCDAGTYIRSLCHHMGLALGCG
                     AHMQELRRTRSGPFREDSAHTLAGLRDAADAFRMGCVRPLREMILPPESALAGLPEVV
                     IRDSAVDALCHGAALAGVGILSSGVFRKGERVAVMTQKGELVCTGQALVSSTQFSPGK
                     PGLVIAPESVFLPRGTYPPGWKKKERRV"
     gene            complement(33028..33720)
                     /locus_tag="PK679_00995"
     CDS             complement(33028..33720)
                     /locus_tag="PK679_00995"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006782 - protoporphyrinogen IX
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HPC54568.1"
                     /translation="MRIAITRLREKATDDRARCAAFGHECYAVSPLEAVVDREAVEVF
                     ACRVNRGDFDCIFFTSALPARLIAPKLERWPRVIAIGPQTKRELEKFGISSEVLDSFY
                     SRDFARYVGDWVAGKHVGIPRADVPNPGLIASIESAGGRVTEILCYSLKPTGIPLPLD
                     DADGLLFTSAMSYRKAVWKPRPNLVLIAIGEVTAGAMEQGGHPPHVVGDGSLEGTLSA
                     LNRVLGSSGRVP"
     gene            33802..35013
                     /locus_tag="PK679_01000"
     CDS             33802..35013
                     /locus_tag="PK679_01000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HPC54569.1"
                     /translation="MMELLAGTAAGVVLGTVSGLLPGIHVNTLAGIMVALLALLLPLF
                     GPVFLAAVLVSALITHCFLDAVPSTFLGIPDADTAVAVLPAHSLCLEGRGEEAVRVAA
                     LGSAAGVVLSIPLCLILIVLMPSIQPAIDWVSGIVILAVITILALHSSAARVSIAVFL
                     VSGLLGIFSFRYAFLSPSPFGGSAVLMPLLSGLFGVSVLLFSGRGAVPPQNFSGIALE
                     NRGIVRGSILGTIAGVFVGWLPGLSNATANGVLASAVDYSRDRREYILATSAANTTNA
                     LVGLAAFFSIERTRNGVVSALSALEVPSLSCLVLSATIAALAAYILTVALAGMAQRME
                     GIDRTRMAAVVIGFVILVAFLTTGPFGLLVLALATAVGCVPRLLGIPQVFCMGSIMLP
                     VLFFSFGIGAF"
     gene            35098..35964
                     /locus_tag="PK679_01005"
     CDS             35098..35964
                     /locus_tag="PK679_01005"
                     /inference="COORDINATES: protein motif:HMM:NF013922.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-processing protein"
                     /protein_id="HPC54570.1"
                     /translation="MPSYWFGDVTGGKCTPAGSHDPEYLSFRLDGIRTEMESFCPPAW
                     EAARDSGFVSSRGEYIRVLREVCIYRAEKALALVAARPEQELIQMVHMRDQLDEVINL
                     VTGRALEWHAARSPEFSRKFRALKGKRALEALVAGGSPRVRGIATGMMHLSEVKADLT
                     REIEQMAGEVIPNCTGLVGGVVAARLLAAAGGLEALARLPAGTIQVLGARTALFAHIR
                     SGSAPPKHGIIYQYRKVHGAKKGRKGKVSRTLAAKIALAARIDYFRGERDEEFLDTAR
                     AAVERAAGESGS"
     gene            35961..36563
                     /locus_tag="PK679_01010"
     CDS             35961..36563
                     /locus_tag="PK679_01010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrillarin-like rRNA/tRNA
                     2'-O-methyltransferase"
                     /protein_id="HPC54571.1"
                     /translation="MIWIDGVLVSRGEGGVYGERMMRGHRVWDPYRSKLAAYYYLGGE
                     VSLESRMRVLYLGAAHGTTVSHVSDSTEVVYAVENAYAPMRDLLAVASRRKNIIPLFA
                     DAAQPSSYAPLVEEVDLLFQDVAHPDQASIALMNLPFLRRGGVALIVVKARSIDVTKK
                     PADVVHEVSHKLAESGLYPRRVIWLEPYHRDHAILECPRD"
     gene            complement(36617..36689)
                     /locus_tag="PK679_01015"
     tRNA            complement(36617..36689)
                     /locus_tag="PK679_01015"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36653..36655),aa:Gln,seq:ctg)
     gene            complement(36772..37485)
                     /locus_tag="PK679_01020"
     CDS             complement(36772..37485)
                     /locus_tag="PK679_01020"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HPC54572.1"
                     /translation="MRCIRAHTLASAHEQVVKMVLEKGTPLTTENGEATVESEEVAIR
                     VEQPDTPPMVSPSSRFSGRFMEQYARDLISGTGSVFEYDYHDRLFNWGEGLYSREGSE
                     IHSDQVAYILRKIQENPSTRRAIAITWNPVRDQSLGDCPCLQLVQCLARGGLLHMKVV
                     FRSNDMLTAAGANMFALVSLQKHIAGKLGLGCGSYTHVSLVPHIYYIRDAADIEPFCR
                     KGEVISPIPEVCRSCGKCR"
     gene            38027..40549
                     /locus_tag="PK679_01025"
     CDS             38027..40549
                     /locus_tag="PK679_01025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MEMAR_RS02690 family S-layer glycoprotein"
                     /protein_id="HPC54573.1"
                     /translation="MIKRFSLALIAVVVLAALMLPASAATIKQVPQGGDVFIGEEGLD
                     VSAAIGTATQVAWFASGNDPATSTPDYVLTVGTPTSFYVSPQTFVGKTGNWYRWTGAI
                     GPVAFNVVDPAIVVKVWDNTAGKDVSGKSVPPGNYLNFRIETNTYSVTARGDAGTQGF
                     VKVRVKTSDGAVYTSLFETTSASYPIDNLRPTSDLWYWRPNPPADGQGWNTGVLDANG
                     ARMYKAGTYTVYAELDLNKIKDNYKAPDGSDYTGKTISSTQTVTITADTVKIEASKDV
                     VVRGNAFSVTITGRPNTEYYLWVKGTGQMSGESLDQPPLLVESQKDVTNDPEGGPYTI
                     GSYQYEGGAGRTIKEDVPAAPSNGVYYYAKVKTSNSGTVTVGWQTSQATKDKKYTFRV
                     ERFDGSAYKSDEVDVKVEKGTVTVVAAGDQSYFLGQEVKLSGTNSETDTVYLFITGPN
                     LPSQGGKLTEPRTGVVNGNAGTFTTADVLDDNTWEYKWQTANLNIDAGTYTVYAVATP
                     SDKNNLADTQYATVSIIIRKPFVTAVASQSTIAQGDKFYIRGVAEGQPSQGVAVWILG
                     KNYVLYSTESVNNDGSFEKEVNQGITSNMAAGQYFVVVQHPMYNDQLDVTPDNSNNPV
                     FVIGPYPTAGSKIFKLQGAGSLQGSDAAEALVTALDNSYVDDTYTKLQFLIEAPVIRI
                     SPITEKAVGEKFEITGTTNLAVDDEILVEVVSSSFKATKKTESGEFSGATGTVKVKKG
                     TEGYNTWSFPVDTANFKPDEYIVQASGVTVDVTTTALFNVVEKPPTTIPTTTPPTTPP
                     TTVVPTVPTTPTPTPTPTSPGFGALVALVGLGAVAFLIVRRH"
     gene            40753..42279
                     /locus_tag="PK679_01030"
     CDS             40753..42279
                     /locus_tag="PK679_01030"
                     /EC_number="2.4.2.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP phosphorylase"
                     /protein_id="HPC54574.1"
                     /translation="MKLTVKLMDIGTREVLLHTEDAGNIGVMPGDRVQILNEGSGVTV
                     AAFVDTTTSLLPKGTIGIYRITNERLQVTDGSAVEVRRAERPVTLDFIRKKMDGEHLS
                     KEETYAIIRDVVEDNLSAAELTAYITACYINEMDMDEVEHLTRAMVDTGERLRFHTHP
                     IVDKHSIGGVPGNKISLLVVPIIAASGLKIPKTSSRAITGAGGTADLMEVLAPVNFSA
                     AEVQQMTEKVGGAIVWGGATNIAPADDKIIIQEYPFRIDARGQMLASVMAKKFAVGAD
                     LAVIDIPVGTHAKVKTVQDGRRLAREFIELGDRLKIQVECAITYGDSPVGRAIGPKLE
                     VIEALRILEGAGSPGSLLQKSVSIAGMALEMSGKAARWKGAEMAAEIVKKGDALKKLR
                     QIIEIQGGDPNVKSDDIEPGRHQFVVNAPATGYVIELNNKALISLARTAGAPHDKGAG
                     LLLHAKKGNRVEKGEPIFTIYAERSWRLQKAIEEGRQLMPVVVEGMLLDRVPQDTRWT
                     "
     gene            complement(42426..42497)
                     /locus_tag="PK679_01035"
     tRNA            complement(42426..42497)
                     /locus_tag="PK679_01035"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42462..42464),aa:Arg,seq:tcg)
     gene            42556..42993
                     /gene="dcd"
                     /locus_tag="PK679_01040"
     CDS             42556..42993
                     /gene="dcd"
                     /locus_tag="PK679_01040"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009394 - 2'-deoxyribonucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HPC54575.1"
                     /translation="MILSASEIRRRIGPDSREGFLVIDPYSEECQQPASYDLRVGGDF
                     ILPPAVCTLVNTLERVELPRDIAATLRCRSTFGRMGVILTAGFVDPGFRGQLTLCLVN
                     MGREHLTLRKNDRVAQIIFFQVTDGEKGYDGRYQDSMGVIQAR"
     gene            42994..43941
                     /locus_tag="PK679_01045"
     CDS             42994..43941
                     /locus_tag="PK679_01045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrpR regulatory domain-containing protein"
                     /protein_id="HPC54576.1"
                     /translation="MIRTERKYIEILRILKEHTEPMGAKRLSELMAERGFVLSDRAVQ
                     YYLRYLDEMGFTKKVGNMGRVLTPYGHEETENALVGDRVGFIISKLERLAYRCSFNPG
                     TSTGDVAYNLSIVPEERLADATAAFDEIVAKKWGFFSGYRVIDNDPRIPHGSAGILSI
                     CSITMDGVFRREGIPVRMAYGGRLAMQHDEATHFVDLIGYRGTTIDPLQLFISSGLTS
                     LSSLVSTGSGTALANVREIPALAENRAREIVARMKKAGFSFPVAMGSSVFNLVLDPYR
                     LALVAYSGMNLVANAYEKKVPIRTEIGAGTIPFSRIIQD"
     gene            complement(43938..45113)
                     /locus_tag="PK679_01050"
     CDS             complement(43938..45113)
                     /locus_tag="PK679_01050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="tubulin/FtsZ family protein"
                     /protein_id="HPC54577.1"
                     /translation="MRILAIGLGGAGSRIIDKLLEHDRMSAIHCVEGLAADSDADELA
                     SLEMVPADRRLFFSPLDPSQPDDIAAHLPKEEILSHLQAMDDGDIDALVLCCGLGGTH
                     ASFAPDLVSFLKKSLVEPVFGLCTLPRGSEGDLCLARALDQLDMLLATLDGIIVFDNE
                     AWKEKVPAITEPETAMDADAIAGKLLEKLRPDIPRKPVDPFHEAMDTLIARRLSLLLR
                     AGECSMREPDNLPEVVLDAGEILNTIQGMGLLTIGYAREELPPARPLDHILRFGPHTR
                     SVRECHVKASRVVDLAKRAVFQEISADTDLSQVKKALVLIAGPSHEMSMKGFMTVRRW
                     LDRSIQGLELRSGDYPVKETRYLGVLVILAGMETLPRIGELRRTRECLEEENGTKKV"
     gene            45476..46465
                     /locus_tag="PK679_01055"
     CDS             45476..46465
                     /locus_tag="PK679_01055"
                     /EC_number="1.5.98.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylenetetrahydromethanopterin reductase"
                     /protein_id="HPC54578.1"
                     /translation="MTTYGIEFVPGAVNVKQVVNYCKLAESKDIDYAWITNHYNNRHC
                     YPTLAMIAANTTTLKMGPGIMNAFTDTPAAMASFVCTLNEISDGRAVLGIGPGDLSTL
                     PKLAINPVKPVARLNEAVTQIRRLVAGEEVKKSGMEFFDYDGAKLTGVTLPGKKGIPI
                     YIGAQGPKVLELAGTVGDGALINASNPKDFAVAIPIIKAACDKVGKKNFDVGAYTAMS
                     IDMNEKKARNAAKIVAAFIAAGSPPELIQRHGLDANKVATIKAALAKFDFKTAGENVD
                     DKIIDAFTIAGTPDTVKQKCEDLAKAGVTQIIFGSPLGPDMTNSIRLLGKYIV"
     gene            46536..47459
                     /locus_tag="PK679_01060"
     CDS             46536..47459
                     /locus_tag="PK679_01060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HPC54579.1"
                     /translation="MFTITEVRSGSTRIQFREEHVSGLRCKISPARLNRRLDAAYVPP
                     PVPARCPFCEGEVERVTPTFSNGTRISVGESLTFPNLFPFAEWHTVTIITRAHSVDGF
                     SPRQIEDALTGQVQSLGGQSGYPSINWNYLPSAGASIAHPHLQGLVDRRPAVLAERYM
                     EGGFRFLIRHGENYWDRLIEHERNSERFLFGDEISWMAQAVPLGEREVRAVLPVSTMP
                     DFEPYIGTFVKGLLSVLRMYRSLGTHAFNMSLFFDSRKTENGFRGFCSVISRINPNVS
                     STSDSAFMERIHQEPVILTLPEELGHYYRKG"
     gene            complement(47539..48378)
                     /locus_tag="PK679_01065"
     CDS             complement(47539..48378)
                     /locus_tag="PK679_01065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F420-dependent methylenetetrahydromethanopterin
                     dehydrogenase"
                     /protein_id="HPC54580.1"
                     /translation="MVVKVGVAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQ
                     PEDIDRVVNNMIAWKPDFAIVVSPNGVLPGPTGARERLAAAGIPTVFITDDVTTKKEW
                     AEIKDGKFGYIIMKGDAMIGARREFLDPIEMADYNGNLIKVLSVTGAFRKLQTALDQI
                     IDQVKAGKKGAELVLPKLVVTSDKAVEGEFTNPYAMAKARAAYEIAQSVAMVNVKGCF
                     MTKEWEKYIPIVCSAHEMMRIAAALCDEARELEKACDGVVRKPHKKDGVIVSKTKLIS
                     KPE"
     gene            48593..48997
                     /locus_tag="PK679_01070"
     CDS             48593..48997
                     /locus_tag="PK679_01070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tfx family DNA-binding protein"
                     /protein_id="HPC54581.1"
                     /translation="MKDSLLTDRQKEVLRYRKQGLTQQQIADLIKTSKANVCTIEKSA
                     MENIRRAKETLEFLYTLDATHLCTIPGGTDLLEVASLIYHEAEKLGIKVRYDTIALIN
                     KIREAAPERFKARFVKENIDVYITEEGDLYFS"
     gene            49575..50588
                     /locus_tag="PK679_01075"
     CDS             49575..50588
                     /locus_tag="PK679_01075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HPC54582.1"
                     /translation="MPKINQPRKGSLAFSPRKRAKSPVPRYQSWPSYQGDPVLQGFAG
                     YKVGMTHVIMVDDHKNSPTEGKDIMVPVTVVEIPPMKVAAIRAYSRDTYGRHPLTEVW
                     AGELDKALGKRITLPKEYDFSGAMEALKDAIAKGVAEEIFAVMHTLPGQVSGVPKKVP
                     EIMEIRVAGGTVQQRFEFIAGLLGKEVHLKNIIQPGAYADITAVTTGKGTQGPVKRWG
                     IKLRKRKHARGGKKRHVGNLGPWNPHHVRWQVPQMGQMGFQQRTEFNKRILKIGENGD
                     EICPAGGFLHYGVLRNPYVLIKGSIPGPVKRLVRIRPAMRQGEHVVRQPAIEFVSTES
                     KQG"
     gene            50596..51345
                     /gene="rpl4p"
                     /locus_tag="PK679_01080"
     CDS             50596..51345
                     /gene="rpl4p"
                     /locus_tag="PK679_01080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HPC54583.1"
                     /translation="MKAQVLSLDGSVLREIELPRVFEEEYRPDLIKKAVIALQSTRRQ
                     PHGTYPYAGILSSAHSWGSGRGVAQVPRIKGGSRAAKVPQAKGGREAHPPVVEKVLVR
                     RINKKEKQKAFWSALAATVSEEIVRARGHVFSAKVPIILEDRFEDLKKTSEVIPVLAA
                     AGVLGDIEKAKVSRKVRAGRGKMRGRRYKQKKSLLIVTGKKPLAAAGNLAGVDVATVD
                     QLNCELLAPGTLPGRLTVWTESAIARLGGEQ"
     gene            51348..51596
                     /locus_tag="PK679_01085"
     CDS             51348..51596
                     /locus_tag="PK679_01085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HPC54584.1"
                     /translation="MVLRYPYVTEKAMMMLENQNKLQFIVDKNATKKEIKREIERAFE
                     QEVTDVSTMMTMDGKKKAVISFANEKAAEEILSRLGIM"
     gene            51606..52322
                     /locus_tag="PK679_01090"
     CDS             51606..52322
                     /locus_tag="PK679_01090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HPC54585.1"
                     /translation="MGHRITTQSRGKGGPTYRAPSHRYKAALRHVNSTGGLVRGVVVD
                     IEHDPARNAPLALVRLENGTKVSILATEGMGVGDQVAWGEGAEVKNGNTLPLAQIPAG
                     TFICNIEAQPNDGGKFVRSGGVQAVVVDRTEDRVGVTMPSGKTKWFSSRCRATVGIVA
                     GGGRGEKPFVKAGKKYHKMKNTASNWPRVRGVAMNVIDHPFGGGGHQHAGRPKTVGRG
                     TPPGRAVGHIAARRTGLSKK"
     gene            52333..52746
                     /locus_tag="PK679_01095"
     CDS             52333..52746
                     /locus_tag="PK679_01095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HPC54586.1"
                     /translation="MAKKTQKRLPRRREEFTYRGFRLDDLRAMGRSELLPVMPSRARR
                     KLVRGLTRGEEHLLTQFRKGEPVIRTHLRDMVIMPEMVGRTIEVHNGKEFVKVEIMPE
                     ALFHYLGEFALTRKKVTHGSAGIGATRSSKYVPLK"
     gene            52752..53213
                     /locus_tag="PK679_01100"
     CDS             52752..53213
                     /locus_tag="PK679_01100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HPC54587.1"
                     /translation="MARTLYSRSFEGDTYARGKVNEIQVSPKHAMEIASFIRNKRISE
                     VIPYLQQVIEGKKAIPFRRFNRKVAHKRGLSGWDAGRFPKKASRAYIRLLNSVIKNAE
                     YLGLDTENLEIVHAAANRGRAFRGIFPRAMGRATPKRRETVNIEIVVREVQ"
     gene            53213..53932
                     /locus_tag="PK679_01105"
     CDS             53213..53932
                     /locus_tag="PK679_01105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HPC54588.1"
                     /translation="MAVERKFVSEGARRARVEKHLKKELKRAGYGGMDLQRTPLGTQV
                     TIFAEKPGIVIGKGGKLVRQLTQDLATDFAVESPQIEVQQVPNPNFNAQIMAERLANA
                     LERGWYFRKAGQSIIRRVMDAGALGCEVIIAGKLTGARARVQKFTEGYIKHSGEPVNT
                     IVEKGYAVAVKKLGVIGVQVKIIPAGAKIPDHFEVTAKREKPEKKGIEIPVVSVGEDL
                     AEDDIPVEPDEFDEEELLRRK"
     gene            53934..54143
                     /gene="rpmC"
                     /locus_tag="PK679_01110"
     CDS             53934..54143
                     /gene="rpmC"
                     /locus_tag="PK679_01110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HPC54589.1"
                     /translation="MAIFRARDVKQLSDVELSEQMEKLKIELIQHYGKVSAGGSTENP
                     GRIRELRRTIARMKTEQNTRRRSVS"
     gene            54140..54424
                     /locus_tag="PK679_01115"
     CDS             54140..54424
                     /locus_tag="PK679_01115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030677 - ribonuclease P complex
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component 1"
                     /protein_id="HPC54590.1"
                     /translation="MILPRNILRHELIGLEVLVTGASNPALHGLSGRIIDETRNTLVI
                     RGDHGTKRVQKAGTRFRVTLPDGVLVEIDGSALVMAPEKRINAIQKTRGK"
     gene            54424..54750
                     /locus_tag="PK679_01120"
     CDS             54424..54750
                     /locus_tag="PK679_01120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HPC54591.1"
                     /translation="MARNIGLSVRPPERECNDAFCPFHGTLPVRGQVITGKVVSDRMT
                     GTVVVERAYLHYVGKYNRYEKRNSKIHAHNPPCIQAKTGDTVRIAECRPLSKTTTYVV
                     VEVQPS"
     gene            54747..55145
                     /locus_tag="PK679_01125"
     CDS             54747..55145
                     /locus_tag="PK679_01125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HPC54592.1"
                     /translation="MKAKQSNIPRALSTGTRLLCADNTGAREVQIVSVFGYHGVRRRQ
                     PKMGLGDIATVSVKKGTPDMRRKLVRAVVIRQKKELRRPNGMRVSFEDNAVVVVDDKN
                     EPKGTEIKGPIAREVAERFPKIGSMATIIV"
     gene            55155..55520
                     /gene="rplX"
                     /locus_tag="PK679_01130"
     CDS             55155..55520
                     /gene="rplX"
                     /locus_tag="PK679_01130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HPC54593.1"
                     /translation="MVRVESKQPRKQRKARYAAPAHARNHFLRAPLAPALREQYHRRS
                     MRVVVGDTVKVLRGESAGTEGLVDMVDTKRSTIVVQGVSVNKADGTEVPRPIPPSNVQ
                     ITRLNLKDPKRAEKLGGAE"
     gene            55520..56245
                     /locus_tag="PK679_01135"
     CDS             55520..56245
                     /locus_tag="PK679_01135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4e"
                     /protein_id="HPC54594.1"
                     /translation="MGDHLKRLNAPDSWHVAKKTSKFIAKTSPGPHNANAMPVAVWLR
                     DHMHLAVNAKEVRQILQQKEVIINGRPCRNPRMGIGIFDIISIPRIGRHFRILRDKKG
                     RHKTIEIDAEAAKSRLAKIRNKTIVPGGKVQLNLRFGANVIADNRYHPGDSIVLSLEP
                     ENRFAILDHFPFAVGNMAMVIGGRHSGKVARIVGIEKVPGSVPNRVILEDPADGSRFE
                     TIDEYIYMVGREEPALKEWGIEE"
     gene            56242..56748
                     /locus_tag="PK679_01140"
     CDS             56242..56748
                     /locus_tag="PK679_01140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HPC54595.1"
                     /translation="MNPMREVFVEKVVVHMGVGEAGDKLTRAVDLLKTITGNTPVRSN
                     AKRTNVSFGIRKGAPISCRVTLRGRKAAEFLSKALDIVDRRIARNQFDRWGNFSFGIE
                     EHTDFPGMSYDPQIGIYGMDINVVLARRGIRVARRSIEQRRLPIKQRVTQDDAARYLK
                     EAHRVEVY"
     gene            56748..56903
                     /locus_tag="PK679_01145"
     CDS             56748..56903
                     /locus_tag="PK679_01145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HPC54596.1"
                     /translation="MGGEKTKVFGRGAHECKICGRKQALVRRYNIMFCRQCFREWAHK
                     MGFKKMN"
     gene            56919..57311
                     /locus_tag="PK679_01150"
     CDS             56919..57311
                     /locus_tag="PK679_01150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HPC54597.1"
                     /translation="MARLNTIADGMCALKNAADGGKSSVIVEPASKLLGAMFRIMQET
                     GYINGFEYIEDGRGGQFRVHLNGRINRCGAITPRYSVRLDELEYWETQYLPGKNFGIL
                     ILSTSKGVITHEQARREHVGGELLGYVY"
     gene            57325..57849
                     /locus_tag="PK679_01155"
     CDS             57325..57849
                     /locus_tag="PK679_01155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HPC54598.1"
                     /translation="MATERTVTIPKGAKIEVDGPTVRVSGPKGQLERTFRFPQITLTL
                     RDDTLVISTTADRKRIVAMVGTIQAHVQNMVRGVTEGFEYRMKVVYSHFPIQLKLSGD
                     RLEINNFLGEKKPRYAQIVPGVTAKVGNDEIILTGIDREKLGITSANIEHATKIKYRD
                     PRTFQDGIYRVQRG"
     gene            57857..58294
                     /locus_tag="PK679_01160"
     CDS             57857..58294
                     /locus_tag="PK679_01160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32e"
                     /protein_id="HPC54599.1"
                     /translation="MAEDTIRAIRVRAAKSARFKRDGFGKKKQLSESWRKPRGLHNKQ
                     RIQKKAKGPLPTPGYGSPLAARGLHPSGYRDVRVHTPAELDGLDPERDAIRIAAGVGA
                     KKRAVIQEKAIKAGLKILNPREEKPVEEPAPAVSEEQEEESDD"
     gene            58287..58739
                     /locus_tag="PK679_01165"
     CDS             58287..58739
                     /locus_tag="PK679_01165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19e"
                     /protein_id="HPC54600.1"
                     /translation="MTDLSSQRRIAAELLSCGMNRVWFDPDRLTDIQNAISREDIRKL
                     IGDGAIIARQIRGNSRGRARALMAKRAYGHCRGPGRRKGAAGARNPAKRQWIRKIRAL
                     RKTLAELREKGEIEPRLYRLLYRQAAGGQFRSVGHLRAHLGIIMGRAR"
     gene            58741..59268
                     /locus_tag="PK679_01170"
     CDS             58741..59268
                     /locus_tag="PK679_01170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011832478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HPC54601.1"
                     /translation="MATGPRYFIPFRRRKEGKTDYYARARLVVSGKPRMVVRRTNRHI
                     IIQLVQAEKEGDLTRVTAHSSELSKYGFRGSLSSTPAAFLTGVLFAVKAQNSGYDSAI
                     LDIGLHRATKGARVFAALKGAVTAGLDVPHGEEILPDDDRVKGVHIAAYAPDRAGDLV
                     QNVEQTMDAIMKELE"
     gene            59270..59887
                     /locus_tag="PK679_01175"
     CDS             59270..59887
                     /locus_tag="PK679_01175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HPC54602.1"
                     /translation="MAYEKVEWVPLTGLGKKVAAGEFSSIDQVLESGRPIKEPEIVDL
                     FLPDLEDEVLDITMVQRMTDSGRRVKFRAVVVVGNRNGYIGFGQGKDSQVGDAIKKAI
                     VDAKINLIKVRRGCGSWECGCNTAHSIPMVVEGAAGSVRVTLKPAPQGIGLVTGEISK
                     KVLELAGIRDVWTFARGQTRTTINFAKATFNALRATNMIRTGGEG"
     gene            59887..60348
                     /locus_tag="PK679_01180"
     CDS             59887..60348
                     /locus_tag="PK679_01180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HPC54603.1"
                     /translation="MYAIVQVRGVVNTRRDIRDTLKMLRLHHINHCVLVPDTPEYLGM
                     IRKVKDFVAWGEVDAETIETILRTRGRIEGNRPLTDEYVRENSSYNGIAELAAALAAG
                     EVRLADIPGVKPVLRLHPPRKGYRTIKRTFPQGGALGYYGKEINELLYKMR"
     gene            60354..60779
                     /locus_tag="PK679_01185"
     CDS             60354..60779
                     /locus_tag="PK679_01185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uL15m family ribosomal protein"
                     /protein_id="HPC54604.1"
                     /translation="MPVNKRSKYRGSRTCGGGTHKNRRGAGNRGGRGRAGHRDHRFSH
                     YWVYGEVHNGKHGFVNPTSDRMRTISVGRLQEMLDELLAAGLASRDGDAIVISAEQIG
                     IDKILGSGKVTEKMRITARAFSGQAKEKIEAIGGQALVI"
     gene            60798..62231
                     /gene="secY"
                     /locus_tag="PK679_01190"
     CDS             60798..62231
                     /gene="secY"
                     /locus_tag="PK679_01190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HPC54605.1"
                     /translation="MGELLDRMEPLLAAMPTVKGPEGHVHFKNKLAWTAGILILYFVL
                     TNIPLFGLNPNSQDIFFYWRALLAGASGSLVQLGIGPIVTASIVLQLLKGADLIHIDT
                     SELHGQIQYMGLQKLLIFVMIIIEAAPNLVGGFLLPDPVIADMFFGGNLFLVSLIIFI
                     QICIGGVLIVFMDEVVTKWGIGSGVGLFIIAGISQAIINGFINWAPVSDQYPVGFFPR
                     MVAVILDSANFLQYMGTDLIAFITTIGIFLVIVYVESTRIEIPLAHAQVRGARARFPV
                     KLIYASVLPMILVRVLQANIQMIGLFLNNVGITILGTFQGATPVSGLMYFLAPINGPD
                     DWMWWIYDLGHAPWEVLLRMGIDILIVVVGGAIFALFWIKTAGMDSRDVARQIQMSGM
                     SIPGYRRNPQVLEKYLDRYIPRVTVIGGVFIGVLSVFANLFGVIGSVSGTGLLLTVSI
                     TYRLYEEIASQQIMEMYPFMRTFFGKE"
     gene            62234..62806
                     /locus_tag="PK679_01195"
     CDS             62234..62806
                     /locus_tag="PK679_01195"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HPC54606.1"
                     /translation="MTGRRVIVTGVPGVGKTTVVTGALKLLEEEGIPYKSLNFGTYMF
                     ETAVAQGLVRDRDEMRRLPGDAQKRLQQLAARAMSKEDGNLLIDTHASVKTPRGFLAG
                     LPEWVLRELMPDTIILVETDPDQILMRRLSDETRARDREGSGAIADHQQFNRAIAASY
                     SMLTGCTIKYITNADHLLDLAVREMADVLR"
     gene            62812..63405
                     /locus_tag="PK679_01200"
     CDS             62812..63405
                     /locus_tag="PK679_01200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EMC3/TMCO1 family protein"
                     /protein_id="HPC54607.1"
                     /translation="MKSRFGGILALMVAMAMIFSYSIAPLREGVGRGLDSVLGPLAEM
                     MPFFILIVILSAITALYSSIIQKYTIDYERMTEVQERMKVFQKEYREAQLSGDEKRIK
                     KLDAKRDRVMKEQLELSQQQFIPMAYILIITVPIFFWLLFRLGVTPHAPIVMPFFGQH
                     TLSEAVLGPVPAWILWYMICSLTISQVIRKSLNIGGI"
     gene            63405..63956
                     /locus_tag="PK679_01205"
     CDS             63405..63956
                     /locus_tag="PK679_01205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HPC54608.1"
                     /translation="MRITVSGLPGSGTTSLARHLAEIRGYRLISAGEVFRQMARERGL
                     DLREFGRIAETEPSIDREIDLRQREIAEREDDIIAEGRLSGWFVGNADLRIWLQAPLS
                     CRVERIFSRDTIQDKETARLLTQEREACEARRYQDYYSIDIRDLSPYHLVLNSETFAV
                     EELSAIVETAIRVIEEKKRGEAR"
     gene            63963..64808
                     /locus_tag="PK679_01210"
     CDS             63963..64808
                     /locus_tag="PK679_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC54609.1"
                     /translation="MRLRILVDNSTHIDRYFLAEPAFSALIETRSGKVLFDLGYSCAF
                     LENARRMGEEILDVRYVVLSHGHLDHTWGLIPYIMALTEARIGKKTVSRPRLVAHPEV
                     FLTKKTGELPETGMLLSEEKCREHFDLELSKEPVWLFSDLVFLGEIPRRFGFEEMVQS
                     GKRMKKSPGGLVPDTLPDDTALAYVGEEGLVIITGCSHSGICNIVAHAREVCGKDKVF
                     DIIGGFHLVGAPATRIEKTVSTLAGMGVTRMHPCHCTGFAARCSFSSAFQVEEIGSGW
                     ECEYR"
     gene            64952..65362
                     /locus_tag="PK679_01215"
     CDS             64952..65362
                     /locus_tag="PK679_01215"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HPC54610.1"
                     /translation="MVVKDWDTNALAMLYRAGGWWKEEWDISEIPRLVRSSFAFVIAI
                     HRESGKTIGMGRALSDGVSDAYIQDLVVLPEFRGSGAGRMILEKLVGVCLSRGITWIA
                     LVAEPGTADFYAGSGFVPMEGHVPMRFRGKENEC"
     gene            65356..66264
                     /locus_tag="PK679_01220"
     CDS             65356..66264
                     /locus_tag="PK679_01220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol lysyltransferase
                     domain-containing protein"
                     /protein_id="HPC54611.1"
                     /translation="MLTISRFRPVTMDDRDVFSRHYAQYPPEHSDNLFSNIACWNHFA
                     HYTYAGHKGCLIISSTVQGVTTFRPPIGPRDREVLLDVIDLAVREGGERPLVLVDEPT
                     TAWIRTLFPDLSLQPDRDYWEYVYLTRDLARLSGGKYLSIRRQLNRFVDRCHHTVEEI
                     NPGNLADVRTFLHEWCEWKQCNEHPFLSYEKDAVIFAIEKFCELGLEGLAIRVGEKIG
                     AIAIFEELNRETAVVHFEKGLPDCEGIYKAINAETARFLEHRYTYINRESDMGVPGLR
                     EAKMRYHPHHMVKVFSVARDDLARLV"
     gene            66624..67040
                     /locus_tag="PK679_01225"
     CDS             66624..67040
                     /locus_tag="PK679_01225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine decarboxylase"
                     /protein_id="HPC54612.1"
                     /translation="MRREMAVRNMKDDDVIWKFKKDKAWGLCTMVDLKQCNPETIRDP
                     EKIHEFIIKLCDLIEMKRFGDPTIVHFGPNAKVAGYSMTQLIETSLVSGHFANESNSA
                     YLDIFSCKEYAPEKTARFCKEFFGAKSMDFNVVFRY"
     gene            complement(67232..67819)
                     /locus_tag="PK679_01230"
     CDS             complement(67232..67819)
                     /locus_tag="PK679_01230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
                     /protein_id="HPC54613.1"
                     /translation="MADFLGSLLYAFSALFVILDPILSVPIFASMTRGQSSAEISKQA
                     VIAVAVAGFLLYIFLFFNFFIFDILGISLPSFQVAGGFLLFILGMQMALGIDIGRPKD
                     HSPSAAGVIIGTPLLCGPGAITTVILLVNDMGILIPAVAIALSLGATWIILRFSAEIQ
                     KLLGDCVTEIMARVLGMLVAAIAVKIIADGIIGLI"
     gene            complement(68265..69614)
                     /gene="ftsA"
                     /locus_tag="PK679_01235"
     CDS             complement(68265..69614)
                     /gene="ftsA"
                     /locus_tag="PK679_01235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F390 synthetase"
                     /protein_id="HPC54614.1"
                     /translation="MGRDPFFDPAIETMSRGDLDALVDERVRYTVAYAQEHSPFYRKW
                     FREHGIEPGAIREHEDLLTLPIVSGKTIRENQPPLTPEFMFRSVSWDEIFTVHETSGT
                     SGTPKSFFLTWEDWKRYAAKYARIFVSQGFGKGDRVVICASYGMNVGANTMTLAARDI
                     GMTIIPTGKCSFPTRILNSYRPTGIVGSVFKLLHLADRLKSEGIDPKETSLERLVVGG
                     ESFSEEARAHLARVWDRNVYNTYGSTEGTMCGECAEQQGLHVPEDLVHLDVYDPALRT
                     FVPDGECGRAILTTLLPPGGRCGTLLINYDTEDTTVVLTRGPCSCGRTHMKIFTPQRE
                     AETVWIHGIPVNRVDIERGVFQPENMDYLTGEYEAFVYAGKDGGIVIRVSMEARDPGA
                     VRREDVEERFLSSFFRYKPGLAPLIGDELEIVFSFLPPGGLELYRVKGRPRRLVDRR"
     gene            69789..70196
                     /locus_tag="PK679_01240"
     CDS             69789..70196
                     /locus_tag="PK679_01240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HPC54615.1"
                     /translation="MKKSRKSDQNVKRYRCRICGYIYSPLRGEPHNGIPAGTAFEDLP
                     ETYVCPICGMEGKGKIGKWGFEEWVPTKYICVVCGYVYDKDRGEPHRGIKPGTPFEDL
                     PDDYTCPICNLDPKISLQFGKVFKQGFEPLYIP"
     gene            complement(70224..70484)
                     /locus_tag="PK679_01245"
     CDS             complement(70224..70484)
                     /locus_tag="PK679_01245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54616.1"
                     /translation="MNGHVLPAGNRKGRADLHETADRWLRAARALPAEDRPYAECLAA
                     MIRSHAIDGIPAIRDPLEAAVFSLLIELVKAREGADGCVRLR"
     gene            70635..71810
                     /locus_tag="PK679_01250"
     CDS             70635..71810
                     /locus_tag="PK679_01250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04083 family peptide-modifying radical SAM
                     enzyme"
                     /protein_id="HPC54617.1"
                     /translation="MKNPFHVMLIPTLGCPARCRYCWSSEPGSPRMSIATVRDVVEWV
                     SSLGKERVTFTFHGGEPLLAGAAFYRDALPLLAEGVAQANPEFAMQSNLWLMTPEIAE
                     ILAEYHVPIGTSIDGPARINDVQRGEGYFEKTMKGYRIAREHGLRVSFICTFTSQSFR
                     EKEEIVRFFRENGFTLKLHPALPSLRNDNPEPWTLSPDDYGDLLVYLLDVSLENLGSF
                     EIMNINDLCKCVFFRHGTVCTFVDCMGSTFAVGPDGSIYPCYRFVGMPEYVMGHVSDC
                     PLPEDLAASPVGEAMQEFRSFVDRACADCPHIRYCRGGCPYNAMVPGHGTIGGVDPYC
                     RAYHRIFDEISGRLNREMAEAPAMEMMCFGAPRQKQDKPGVMALMRFQAMKEGRRKR"
     assembly_gap    72391..72490
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(72530..73567)
                     /gene="mtrH"
                     /locus_tag="PK679_01255"
     CDS             complement(72530..73567)
                     /gene="mtrH"
                     /locus_tag="PK679_01255"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit H"
                     /protein_id="HPC54618.1"
                     /translation="MFRFEKEQKVWDFNGTKIGGQPGEYPTVLACSIFYNKHEIVLDE
                     KTGKIDKAAAEALWNRCQELSDMVGIPHFIQILAEYPQAFESYFQWFDSIDNKTAFLM
                     DSSVPACLAHACKYVTEVGLAHRAIYNSINGSILPENVEALKNSDVDAAIVLAFNPAD
                     PSVAGREKVLVEGGVAGQAKGMLQIAEECGITRPILDTAATPLGLGSGSAYREILACK
                     AIHGYPTGGAYHNMTVAWTWLKRWKGSKKNPSQLVESLKGKDIYLKQLLHHYQGGIEG
                     VVQAAWSAPDIGCNLVASTLGADLIMYGPIENVEPMITAQAYMDIVTLEAMRPLGIDC
                     KAENHPIFKLI"
     gene            complement(73585..74325)
                     /gene="mtrA"
                     /locus_tag="PK679_01260"
     CDS             complement(73585..74325)
                     /gene="mtrA"
                     /locus_tag="PK679_01260"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit A"
                     /protein_id="HPC54619.1"
                     /translation="MAEKKSPASGWPIVQGDFHAGDPQSPVAVMTCGSHLDEKAICDG
                     GAAIAGSCKTENLGLEKVIANIISNPNIRFLLLCGTEVKGHLAGQTMAALHKNGVKDG
                     RVVGAEGAIPFIENLKEDAIKRFQEQVELVNIMEAEDLGAIKAKIAELKGRDPGAFAA
                     DPMVVEVKESAAGGVEVAAAGVNPQFLEIERRLDKIEKKIEFVDAEVAQRVGRKIGRD
                     IGILYGLVAGLTVFVMLLVLLPKLNMMM"
     gene            complement(74331..74537)
                     /locus_tag="PK679_01265"
     CDS             complement(74331..74537)
                     /locus_tag="PK679_01265"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit F"
                     /protein_id="HPC54620.1"
                     /translation="MAEEGQKMTGPIRMVAIENMMENIRYKAQLIARSNKYDSALLGS
                     GIIGFAAGLLTALILIVVPAIGMR"
     gene            complement(74544..75269)
                     /gene="mtrA"
                     /locus_tag="PK679_01270"
     CDS             complement(74544..75269)
                     /gene="mtrA"
                     /locus_tag="PK679_01270"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit A"
                     /protein_id="HPC54621.1"
                     /translation="MAEKKSPASGWPIVQGDFHAGDPQSPVAVMTCGSHLDEKAICDG
                     GAAIAGSCKTENLGLEKVIANIISNPNIRFLLLCGTEVKGHLAGQTMAALHKNGVKDG
                     RVVGAEGAIPFIENLKEDAIKRFQEQVELVNIMEAEDLGAIKAKIAELKGRDPGAFAA
                     DPMVVEVKEAAGGGAEEAGGVVQPMSGELALIHARMKVIEKMVTDIGYRDKFAAGVYS
                     GKIEGIMIGLIVSFAILGFMLMG"
     gene            complement(75280..75561)
                     /gene="mtrB"
                     /locus_tag="PK679_01275"
     CDS             complement(75280..75561)
                     /gene="mtrB"
                     /locus_tag="PK679_01275"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019386 - methanogenesis, from carbon
                     dioxide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit B"
                     /protein_id="HPC54622.1"
                     /translation="MYVQVLPEYGLVCDPMIGVVTTAGESLAPIIEKVGDLEAIADDM
                     VNMLAGEGNFLASFPNRENALPTAGAATAYWYGLAVGLLIAGVYVFHLL"
     gene            complement(75563..76411)
                     /gene="mtrC"
                     /locus_tag="PK679_01280"
     CDS             complement(75563..76411)
                     /gene="mtrC"
                     /locus_tag="PK679_01280"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019386 - methanogenesis, from carbon
                     dioxide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit C"
                     /protein_id="HPC54623.1"
                     /translation="MTVKVEVVEGGIPHNTIMAAGLVASVIFVYLTYANVLAQTQLFS
                     FFGGLAAVAAITWGSHTIKHLCSYGIGTGVPSAGMMAFGSGVIAMLFATKFGVASPIV
                     AVVLAAVIGAILGFLANNVLNMRIPVMIQSLTEMAIVGALVLMGFAAMMTGSFEFTPL
                     TAGSITIMGLSLPSYQASFIGGSLIAVAFMLGGIAVQHPFNACLGPNWTQDRMLTLAQ
                     ECGFLSMITAAVMSMALVSLAAGLVSLVVALIGWYYTYTKYIDLSKRDAAAWLDAKPI
                     PELEGH"
     gene            complement(76422..77258)
                     /gene="mtrD"
                     /locus_tag="PK679_01285"
     CDS             complement(76422..77258)
                     /gene="mtrD"
                     /locus_tag="PK679_01285"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0019386 - methanogenesis, from carbon
                     dioxide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit D"
                     /protein_id="HPC54624.1"
                     /translation="MSAIGAKPAAGAAMDIPSTIAGIILLLVIVGATYFLVGPGMMFY
                     ALIGVIVGGLLIAFGVHFVPVGGAPAAMGQAPGIATGVAMLAAGAGLAGLFGGAWAAE
                     QGLVVAVITGAVGGGLMMAITCMFVTFIYVFGMGIPCASGKVAKDPITGDTQTEFKSQ
                     GTEGHGLPFVSYVGGVIGGLLGGGGGTLIYIMLLDVYKEALPGMMKALPAQVLPIAVS
                     LAGIFAIGMFLVNAVLTAYNITGTIEGPHDPKFKRFPRALVASAVASALCGMVAILIV
                     AM"
     gene            complement(77263..78162)
                     /gene="mtrE"
                     /locus_tag="PK679_01290"
     CDS             complement(77263..78162)
                     /gene="mtrE"
                     /locus_tag="PK679_01290"
                     /EC_number="2.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030269 - tetrahydromethanopterin
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0019386 - methanogenesis, from carbon
                     dioxide [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydromethanopterin S-methyltransferase
                     subunit E"
                     /protein_id="HPC54625.1"
                     /translation="MESIAFGIGITALAGALATVAGAAENTESDIGSQGDPNSQVQLA
                     PQMGYIHRIFNKAIAGEPPAYGLWVALGAGLAWAFMAMQVNPILAIVLGSALAVFVQG
                     VYATTAYLGRIASLSKFGQPVFIDVLKSMTTVTMAHAFVAIFTTVTICHLINAALGHP
                     FPLPLLGLVWGIALGAAGSATGNPFYGKERQYQTQKFGAGVPIAASGNIVRYAEAGER
                     NSLDNGWFSAKLGGPASGLCFGLIVFLELWRTVLFEKVGAGWGAIIVGIIIILVFTVI
                     DRYIEVWARKNYGPYGEPAKEGS"
     gene            complement(78479..80182)
                     /gene="mcrA"
                     /locus_tag="PK679_01295"
     CDS             complement(78479..80182)
                     /gene="mcrA"
                     /locus_tag="PK679_01295"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     alpha"
                     /protein_id="HPC54626.1"
                     /translation="MAKKIERTQKLFLKALKNKFAEDPQSTTTVYQRIGLKQSARKME
                     FVKAGKTAEMARGISMYDPVRCHLGGIPLGQRQLMTYEVSGTGVFVEGDDLHFVNNAA
                     MQQMWDDIRRTIIVNMDLAHQTLQKRLGKEVTPETINEYLHVVNHAMPGAAVVQEHMV
                     ETHPGLVDDCYLKVFTGDDEMVDDLEPQFVINIEKLFPAKQAAQLKAAVGKSMWQAIH
                     IPTIVSRTCDGGTTSRWSAMQLGMSFIGAYRMCAGEAATADLAFAAKHAGVIQMGEIL
                     PARRARGPNEPGGIKFGHFADMVQTDRKYPNDPARASLEVVGAGTMLFDQIWLGSYMS
                     GGVGFTQYATAAYTDNILDDYTYYGMDYIKQKYKVDWQNPNEKDKVKPTQDIVNDIAT
                     EVTLYGMEQYEHFPTALEDHFGGSQRASVLAAASGLTTAIATGNSNAGLNGWYLSMLL
                     HKEGWSRLGFYGYDLQDQCGSANTESIRADEGCVGELRGPNYPNYAMNVGHQGEYAAI
                     CGAAHYTRGDAWTLNPLIKITFADPSLKFDFAEPRREFARGAIREYMPAGERSLIIPA
                     R"
     gene            complement(80188..80952)
                     /gene="mcrG"
                     /locus_tag="PK679_01300"
     CDS             complement(80188..80952)
                     /gene="mcrG"
                     /locus_tag="PK679_01300"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     gamma"
                     /protein_id="HPC54627.1"
                     /translation="MAYKPQFGPGTSTVAENRRRVMDPTKKLEKVRDISDEDIVLIMG
                     HRAPGAAYPTSHPPLTEQQEPDCPIRKLVTPLDGAKHGDRIRYIQFADSMYNGPCQPY
                     LRSYIAAYRYRGVDPGTLSGRQIVECRERDLEKLAKELVATEIFDPARTGIRGATVHG
                     HSLRLSEDGMMFDMLQRCILDKKAGVVKYVKNQIGEPLDKEVKVGKPMDEKWLKQHST
                     IFHSLVGVPFRSDQEYIEYVQRVHALRTKYGFMPTE"
     gene            complement(80966..81586)
                     /gene="mcrC"
                     /locus_tag="PK679_01305"
     CDS             complement(80966..81586)
                     /gene="mcrC"
                     /locus_tag="PK679_01305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-coenzyme M reductase I operon protein C"
                     /protein_id="HPC54628.1"
                     /translation="MPMGRVTQVVDCRETMGMGKGGGIAQRGTISECRYPDVIVVGMS
                     PGRRHVTKPVCDITSALRQQGVEYSISTLVLNAGSGVPPDAANIGGAVLGAYFGLTEK
                     EIGQIEKHRVAILHHGNVRSHVVHKVRFILQACDIKAIVVSQAPVDFEDFAKEGVKTA
                     LVMPPPDRVKTKGTVMAIVSGVTRGQTPTREKMAEVIHAVLRLIKN"
     gene            complement(81588..82055)
                     /gene="mcrD"
                     /locus_tag="PK679_01310"
     CDS             complement(81588..82055)
                     /gene="mcrD"
                     /locus_tag="PK679_01310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-coenzyme M reductase operon protein D"
                     /protein_id="HPC54629.1"
                     /translation="MTDAIYPQVRIVTERLMNPETVERVMNLIIGTGGVRRVILNGPR
                     LPPTVPYGPAKGLPNPTEYRKKIKIGDQDVQLEVHVGNIVLELENRDFIPAIREACEK
                     GITKFSWYLQEGRFMKTAPSLVDYAKYGPDADRDIIGLTEPGKSGLVILQGTK"
     gene            complement(82070..83383)
                     /gene="mcrB"
                     /locus_tag="PK679_01315"
     CDS             complement(82070..83383)
                     /gene="mcrB"
                     /locus_tag="PK679_01315"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     beta"
                     /protein_id="HPC54630.1"
                     /translation="MAKYKDTCDLYDDNGKLLKSGVSLDKISPLNNEGILKIIDLTKR
                     TVAVNIAGIDNALKTGAMGGKNNQILGRAIKCDCVKDVDALSEKIAEYVSVSKGDDTK
                     ITKVGGGKMLLVEVPSARLKAAATYDAATTAVAAATTLALVEQYKVGMWDAPYVKSAV
                     WGSYPVTMDMAGGNIISVLSIPQNNEGLGYALRNIPANHVAMMTHRNAMQTAALSCTY
                     EQAGEFEMGMAIGPFERAQLLAYAFQGLNANNLVYDLVKANGKTGTIGTVVQSLVERA
                     IEDKVIKPGKKGKSGYIFYETKDPMLWNAYACAGTMAATMVNCGAGRFAQAVSSVLLY
                     FNDLLEHETGLTSADYGRVMGTAVGFSFFSHSIYGGGGPGVFNGNHVVTRHAAGVAVP
                     CVCVACALDAGTQMFGPEQTSKVYQDTFGQLDVFKKPIQSIAKAV"
     gene            complement(83732..84532)
                     /locus_tag="PK679_01320"
     CDS             complement(83732..84532)
                     /locus_tag="PK679_01320"
                     /EC_number="1.2.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018493 - formylmethanofuran dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit C"
                     /protein_id="HPC54631.1"
                     /translation="METVTITMKNQPKLYLEADNISPDKFAGKKASEIAALHAYEGRE
                     QTTLGKYFEIAGEGGATAAETRIVVKGDVSRVKYIGMKMSAGEVLVEQSPDMYTGAWM
                     QGGKLVVKGNVDSFAGIGMKGGEFLIEGNAGDYLGAAYRGDWRGMQGGLIRVKGNAGS
                     DIGYFMNGGTIIVHGNSDVHVGTHMEGGRIIIKGNAPSKVGGQMVGGEIFVYGTIDVM
                     MPGFKYVQDEEVEVDGEKALFALYHGDTGERHPKRKGQIVYGKLYLKI"
     gene            complement(84542..86251)
                     /locus_tag="PK679_01325"
     CDS             complement(84542..86251)
                     /locus_tag="PK679_01325"
                     /EC_number="1.2.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit A"
                     /protein_id="HPC54632.1"
                     /translation="MAEYIIKNGFVFDPTQGIKGDKADIAVKDGKIVKSTEVSSKAKT
                     IDASGKTVMAGAVEIHAHIAGPKVNEGRNYRPEDKLFTYRPKSASSRMAGGFSIPTTF
                     KTGYEYARMGYTTAMEAAMPPLYARHVHEEIKDTPIIDEGAYPVFGNNWFVLEYLKNK
                     EIENTCAYISWLLEATKGYAVKVVNPGGTEAWGWGLNCLTIDDPVPYFDITPREIVTG
                     LIEANEALGLPHSVHIHQNSLGNPGNYTVTLDTLKLAEGFKAKNKFGREQVLHSTHLQ
                     FHSYGGDSWANFESKSKEVMDYVNKQKNITVDTGCVTLDETTTMTADGPFEHHLTELN
                     HLKWANVDVELETAAGIVPYIYSPDIKVCEIQWAIGLELALMAKDPMRCFITTDHPNA
                     GPFTRYPRIIKWLMSAEARKKQIESFKHSAKMVEATHIAGIDRELSLYEIAQMTRAGP
                     AKALGLSRQYGGLAPGMDADIVVYDFNPEKPHKPEDIEKAFSAAAYVMKTGVPVVING
                     EIVSNGNKRTLWVKAKVNENPQVMRDIRDKFLRYYSVTQANYDVSSHFVPNPHVIEVD
                     ATH"
     gene            complement(86252..87568)
                     /locus_tag="PK679_01330"
     CDS             complement(86252..87568)
                     /locus_tag="PK679_01330"
                     /EC_number="1.2.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit B"
                     /protein_id="HPC54633.1"
                     /translation="MSKSVTDVICPFCGTLCDDLEVIVSDDGKKIEDIYNACAIGAEK
                     FMHAQAPERVKRPRMQQPDGTYKEVSYDEAVEYTAQMLFNARKPLMYGWSSTSCEAQS
                     VGHEIAEKVGAIVDNTATVCHGTTLIAVQDVGIPSCTLGEIKNRADRIIFWGCNPCHA
                     HPRHQSRYSVFPRGFFTNKGHMNRKVIVVDPRVTDTAKLADYHYQVEQGRDYELLSAF
                     RVALRNEPLPETVAGIPREKIIEGAEVMKSGRFGIIFFGMGVTQSLSKNHNIDNAIML
                     TKDLNEFTKFSIMAMRGHYNVTGSGQVLGWQFGYPFSVDLSRGFARYNPGETSSNDLL
                     RRGEVDAVFVLGSDPGAHFPISSVKKIAELPSVCVDPHITPTSEISKLHVPVAFVGVE
                     VGGNCYRMDNVPIEARKVVDPPEGVLTDVEFLTRVNARLDQLMGGK"
     gene            complement(87568..87969)
                     /locus_tag="PK679_01335"
     CDS             complement(87568..87969)
                     /locus_tag="PK679_01335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin dinucleotide binding
                     domain-containing protein"
                     /protein_id="HPC54634.1"
                     /translation="MAKLKLNLITGRTIHQGVAMEGGKEKDAYTKACGIIEMDPSDLK
                     KLGIWKGTNVRVTSEWGSVVVKAVEATQGPHPGLAYIPMGPWANSVVNPKTYSTGMPT
                     FKGVPIEVEPAINEPVLSSIQLVQKKCRGEA"
     gene            complement(87987..88412)
                     /locus_tag="PK679_01340"
     CDS             complement(87987..88412)
                     /locus_tag="PK679_01340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase iron-sulfur subunit"
                     /protein_id="HPC54635.1"
                     /translation="MAEQEWKPKILGIICNWCSYAGADLAGSARTQYPPDIRIIRVMC
                     TGRIDPLFIMKAFVDGADGVLVSGCHFGDCHYLEGNYKAAKRMFILKSLLRNIGLEDK
                     RLRMTFVSASEGAKWAVVVKDVVDTITNLGPSPLKEIGR"
     gene            complement(88412..90529)
                     /locus_tag="PK679_01345"
     CDS             complement(88412..90529)
                     /locus_tag="PK679_01345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase iron-sulfur
                     subunit A family protein"
                     /protein_id="HPC54636.1"
                     /translation="MAEKKTRKEPAAKKDTKKAVSKATHAPAPAATSPDKDLGKGARI
                     GVYICHCGTNIAGSVDILAVQEYAKTLPNVAHVDNYQYMCSTPGQKKIEQDIKEHKLT
                     GIVVAACSPRLHEPTFRTATKTGGLNPFRFEMANIREQGSWVHMHDREGATAKAKDAI
                     RIAVAKAALLQDLVPKSVPVTKAALVVGAGVAGMQAALDLANAGIKTYLVEKSPTIGG
                     RMSQLDKTFPTLDCSQCILTPKMVDVGRNPNIELMTYSEIEEVEGYIGNFDVTIRKKA
                     RGVLTPAEAEARGIVGGGCNGCGDCDTVCPVIKPNPFEMGMKPRKAIYIYHPQVVPLI
                     YTVDFDSCVKCGLCVEACGEKKAIDLEMKDELVKVKVGTAILALGYDIFPIEKKEEWG
                     YKKYENVVTSLEFERLICASGPTGGHLVRPSDGKTPKKVAFLLCAGSRDNTGVGKPYC
                     SRFCCMYSLKHAHQIIEKIPGCQPYIFYMDIRSFGKMYEEFYYRIQDEGAKFIRGRVS
                     NVLEDPVTKNLYVMADDTLLDRPMKLEVDMVVLAAAVQPSADTDRTRKLFGVSCSLDG
                     WLLEAHPKLNPCGTTTAGVFLAGVCQGPKDIPDTVASAEGAASAASIPIHMGEVELEP
                     YFAQCIEEKCAGCGMCVNLCPYQALSLVEKEGRKVMQVTEAKCKGCGTCGGFCPGGAI
                     WMQHFATPQIVAQIDAFLLGGEQ"
     gene            complement(90543..91433)
                     /gene="hdrB"
                     /locus_tag="PK679_01350"
     CDS             complement(90543..91433)
                     /gene="hdrB"
                     /locus_tag="PK679_01350"
                     /EC_number="1.8.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase subunit B"
                     /protein_id="HPC54637.1"
                     /translation="MREYAFFLGCIAPNRYPGAEAASYKTAERLGIKLLDLEGASCCP
                     APGAFGSIDLNVWYAMAARNLVLAEQMKKDIALICNGCYKSIWEVNHKLKHNKELRDG
                     VNEVLKGIDMEFKGTIDVWHLAELFYDPNIVGVDKIRDSVKVPLTGTRIAVHYGCHLM
                     KPRKERHFGTTEHPTWLEEMVAALGAEPVEYRNKMLCCGAGGGVRGYDLVHSLDITNE
                     KMINLREAGVDALTEVCPFCQLQFDRGQIEMEEKFGVKYNLPVLHYCELLGLAQGMTP
                     QELALDLHAISCEPFLKKVL"
     gene            complement(91440..92021)
                     /gene="hdrC"
                     /locus_tag="PK679_01355"
     CDS             complement(91440..92021)
                     /gene="hdrC"
                     /locus_tag="PK679_01355"
                     /EC_number="1.8.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase subunit C"
                     /protein_id="HPC54638.1"
                     /translation="MARTKGYPEPLEKKLRDTRLYEEDTNPQFTKTVEKISMTIPHMC
                     YQCGTCTASCPSAPRSSYRIRKFVRRALLGLEEEALTDPDLWLCTTCYSCTDRCPRDI
                     APTDVIMAMRNLAFKRDIIPVNFLKTVQAIYTTGHGVPNNDVNRAARKKLGLHPEPPT
                     THRFAQYIKGIQYILDYFELKKNADRIVKEREG"
     gene            complement(92032..93195)
                     /locus_tag="PK679_01360"
     CDS             complement(92032..93195)
                     /locus_tag="PK679_01360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC54639.1"
                     /translation="MTLFPKFKKIRDGMNVICEQRLLQQVNNLVLNSEVCTGCGICVE
                     ACPEEAIALGLVGATRRGAVGYASPVDIDEVKCSYCGVCVVMCPFNALTLKIDGEERL
                     PIVEKDGFPQYDMVADIDDEKCVRCTICDEVCPREAIIRDVPVYEGAKEDGKERQEAL
                     KSKTTFKVDDEKCTLCGICGAVCPAITVKHKPFTAETGKVEGEVVWDETRCDACKVCV
                     ELCPEECITVEREVIEGKKLPGQVDIDQKMCCTCTWCSRNCPTEAITVEKLFEGDIEF
                     FPEKCPGGCSTCVEVCPANAIYLPTPVKASEMKGKVEPTIAVNKDYCILCGACVNACP
                     GEDIIRLHRTGIRIKGKETDLFKKIKEKLCTPRTSKVKEETPGSVQLKMMEKA"
     gene            complement(93230..93493)
                     /locus_tag="PK679_01365"
     CDS             complement(93230..93493)
                     /locus_tag="PK679_01365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011832614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC54640.1"
                     /translation="MAFALHVNMDRCTGCNNCVVACPVDALELFTVDPATNEKIYKVR
                     HGKAMVLDFKQELCAGCGVCVEACPHDVIRLAGRGAVPSEAKV"
     gene            93905..94789
                     /gene="fhcD"
                     /locus_tag="PK679_01370"
     CDS             93905..94789
                     /gene="fhcD"
                     /locus_tag="PK679_01370"
                     /EC_number="2.3.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran--tetrahydromethanopterin
                     N-formyltransferase"
                     /protein_id="HPC54641.1"
                     /translation="MQLNGVTIDDTYAEAFPTWIARVIITAATLEWARKAATEATGFA
                     TSAIGCPCEAGIECELSPDETPDGRPGVAILICAGKKKLKEQVVERLAECVLTSPTTA
                     VFNGLLNTEEKIPVKLHFFGDGYEYQKEVGGRKCWVIPIMEGEYVGEEEFGIVKGVAG
                     GNFFVMGENQMAALMGAQAASDAIARVRGVITSFPGGIVASGSKVGSNKYKFMPASTN
                     EKYCPTIRDKVPDSKVPAGVNAVYEIVIDGLDEKVVAEAMAKGIKAAVRVPGVKFISA
                     GNFGGNLGPYKIELHKIL"
     gene            95049..95960
                     /locus_tag="PK679_01375"
     CDS             95049..95960
                     /locus_tag="PK679_01375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1743 domain-containing protein"
                     /protein_id="HPC54642.1"
                     /translation="MTGRDVPLLEDPYIIRYPEIVAVTDKEGRQVELVEFFECTGGAM
                     WVQEHYAKSPLVRSVRTVGSSTRYILEPGTVDLDLVGSRFPAGISGVSVEGDEIAISY
                     VGLGGGGVGASGCRSLAGGVIRSRADPSGGGKKAGATVWLPRRERVLIGVDDTDTPQE
                     GATWTLCHNIARAVQDEDSRYLSHTIVQLFPVPYRTKNCVAVVCEFASRNPDRLVSAF
                     QRLLATHTLSSETGMAVFRGFDPGPLLGEFGWAVKRGEVSRERLDALGRDGLEFIMRG
                     RGLIGAAASIPFYTRYKEALRLCDGKN"
     gene            95942..96916
                     /locus_tag="PK679_01380"
     CDS             95942..96916
                     /locus_tag="PK679_01380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC54643.1"
                     /translation="MRWKELKADLLSVGTARLAGEPAGKYVSRSAAGPGAGGPGSVFF
                     SLEGKRVRLSLDSESPVLITHTGEGRAVLEYRGREVRGRLEEVALHCPRQAYLTVSSG
                     CIFSCRYCGVPGNPMERKSVREIVELVRQVADRVDAISLTSGVIGSVEEEERYVLEVV
                     RQLRQQFSLPIGVSIYPTERTPERLHSLGVTEVKFNVETATDNLFEEMCPELSRDAIW
                     DALSRSVPLFGKNHVFSNIIIGLGETDGEAVSCIRRLAGMGVIPVVRPLTPAAACRNL
                     PRPSQERLLALFRVHSDTLRDAGLDPREAVSMCAACTGCDLVPGRDDS"
     gene            96913..98199
                     /locus_tag="PK679_01385"
     CDS             96913..98199
                     /locus_tag="PK679_01385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HPC54644.1"
                     /translation="MKGEEALARAILTATDRRYTVPGYPITGLATRCNAEMVVNEKTG
                     LEYALGDSLSGKRAALIVKNVGVNACVDPLVQATAQGLIGGVLLVAGDDPAAAGSQTS
                     QDTRIIGELAEIPVLEPGPESCFSAVEAALEASEEFSRVAMLRVTPALLEAEATGDPV
                     PRRDKKGSLSDRSYTMHGRVTASRRLFARMQEWALHSPLNTWQGGAAGIGPRPGETRV
                     VTVFPPPSILGQYTEIREEGLPFAGDHCRHRFLPDPAEEEPETLESRGYYRTFCRDCP
                     FWPVIALMKEEGLRPVCDAGCVVMAMNPPYRVGVASYGMGSSIAVAARSTGFALTGDY
                     ALLHSGINALIDVYEKRIPLLCVVLDNRCAAMTGKQASIPIDPYLEWARPHYTDASEI
                     GRLRELFRTAQRPGVIVIRGECPEGQDHEIVAYRNL"
     gene            98171..99301
                     /locus_tag="PK679_01390"
     CDS             98171..99301
                     /locus_tag="PK679_01390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase family protein"
                     /protein_id="HPC54645.1"
                     /translation="MKSWHIEICDVTLRDGEQTPGVSFTCEEKVRIAEVLDQIGVEVI
                     EAGFPATSSYEKRCVSSVAALDLDARICCLARARKGDVDAAIDAGVDMVSIFIPTSEL
                     HVRHKFHAPREKVLADALEMVDYTRDHGLQVRFAAEDASRTDLPFLLEVYRQGEEHGA
                     DLLSFADTVGALSPLEMYRMMRKIVRAVKKPLCAHCHNDMGMATANTIAAAQAGAFQL
                     HTTVNGIGERAGNAALEEVLVALYMKGNIRRYDLSHLTTLSAMVAQYSGIPVDKLKPV
                     VGEHAFRHESGIHIAAILEDPSTYEYFPPGLVGATRKFTLGKHTGKKALEHEVARLGY
                     SLPEKDLCRVLELVKDRGEKKVELTDETLIDLIKMVMGGPPL"
     gene            99298..100512
                     /locus_tag="PK679_01395"
     CDS             99298..100512
                     /locus_tag="PK679_01395"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitase/3-isopropylmalate dehydratase large
                     subunit family protein"
                     /protein_id="HPC54646.1"
                     /translation="MTTLSERILGAPAGSYVDCRVDRCYVHDGTGVLTLEAYQAMQAE
                     RIARRDRTYVLFDHIVPANNSVTAGLQAELRRFARDRGLPFTDVGEGICHQVMGEGIV
                     LPGEIVVGADSHTCTLGAFGAFATGVGATDMAAIWADGGTWFRVPETIAIFLSGSLKE
                     PAEAKDLALTYVSRLSMDGATYKALEFVGDGVQSLSMESRMTLSNLAVETGAKAGLFY
                     ADGTTCAYLGDYGHSVSPQVPDESSYPQRLEIDISDIVPVVAVPPRVDTVRPVGDLAG
                     LPLDQVFVGTCTNGRYGDLERFARIVRGKKVRVRTLVAPASRRVLARASATGVLSWLI
                     EAGCTILPPGCGPCLGAHQGVLGEGEVCLSTANRNFRNRMGVGGEIYLASPATAAASA
                     LAGALAVPEVPR"
     gene            100509..100979
                     /locus_tag="PK679_01400"
     CDS             100509..100979
                     /locus_tag="PK679_01400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase"
                     /protein_id="HPC54647.1"
                     /translation="MKVEGPAVCLGADIDTDIIIAGRYLRTKDRSVWATHVFEDMDPA
                     LASRLRGAVIVAGKNFGCGSSREQAAIALREAGVRCVIAPSFARIFFRNAINTGLPVM
                     ECECPCMEGKKVVADPVSGRIEIGDRVFFARPLSPRMLGILSAGGLVEYWRKKR"
     gene            100976..101776
                     /locus_tag="PK679_01405"
     CDS             100976..101776
                     /locus_tag="PK679_01405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54648.1"
                     /translation="MIFPRECKVVGHAGDSPCGENVYFLTKFLLRETNGGMELLEVTT
                     DPLATGMMRPVLETRVLAVPEEVMVYPRRVQIHNRARLVELALESGKRCTVFTGHDEH
                     MTFVLDPDPAAFLKIHVYDIVPPRPSLSSTIRELEEAGMFGELDIAFIHTLRDISQVD
                     ADVFPCRAAGFSRTLDADPVSRHEKVAGCLTGSQLVRECYGEGIEVIDICPLRMVREE
                     PFITRCCRKEREGLRMVNGKNGIVVHWGAGPAEIYRAVISLVRGKGEG"
     gene            101773..102744
                     /locus_tag="PK679_01410"
     CDS             101773..102744
                     /locus_tag="PK679_01410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HPC54649.1"
                     /translation="MRIAVVEGDGIGHEVIPVAKRALEVLRPDFEFYSVDVGFGKWQR
                     CGEAITSQDMEDLSSADAILFGAITTPPDPGYRSVIVQIRKTLDLYANLRPVFGKGFD
                     IIIVRENTEGLYSGVEKIEEDSACTVRCITRRGSERIARCACRLVKKRRELTIGHKAN
                     VLKADAFFRDICIAEARKAGVPFRECYIDALCLDVLQHPERYDVILTENMFGDIISDV
                     AAFLVGGLGVLPSGNIGDQHALFEPVHGSAPDIAGKNVANPIAALRSAGMLLSYSARD
                     PVSAQRIEEAIGRILAQGIRTRDLGGNATTTEFGDHVILELESMNRA"
     gene            102827..103198
                     /locus_tag="PK679_01415"
     CDS             102827..103198
                     /locus_tag="PK679_01415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC54650.1"
                     /translation="MGRILLVDDSEMARFLLARFLTGGGHEIVGEAANGIEAIEKVRE
                     TAPDLVILDLIMPQMKGIQTLEEIKKVSPKTSVVICTGDHQEYTVREAVRKGASGFII
                     KPFDKDIVLDEINTVLAGKQP"
     gene            103363..104205
                     /locus_tag="PK679_01420"
     CDS             103363..104205
                     /locus_tag="PK679_01420"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016888 - endodeoxyribonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HPC54651.1"
                     /translation="MVRVGVHISIAGSIAQSVGRAQAISCDTFQIFSRNPRGWKYKEI
                     PVEEAEAFRSALAMSGIKPVFDHMPYLPNLASPKEDIYEKSCAALSAELQRCGQLSIP
                     FLVTHLGHHLGEGADPGRGRVVEAINSALSGAPPGVMLLLENTAGEKNSVGSTFEDIR
                     AVLDGIEYPSHVGVCFDTCHAFGAGYELRSPEGIEETLATLDEVIGHPLVRLIHLNDS
                     RGERGSGLDRHEHIGLGSIGEEGFSLMLHTDFFRKRPLICETPVDDRRDDRGNIAKVR
                     ELAG"
     gene            104296..105297
                     /gene="endA"
                     /locus_tag="PK679_01425"
     CDS             104296..105297
                     /gene="endA"
                     /locus_tag="PK679_01425"
                     /EC_number="4.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000214 - tRNA-intron endonuclease
                     complex [Evidence IEA];
                     GO_function: GO:0000213 - tRNA-intron endonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006388 - tRNA splicing, via
                     endonucleolytic cleavage and ligation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-intron lyase"
                     /protein_id="HPC54652.1"
                     /translation="MKATFDGEHVRLGAEGKSLYEQSGYGRPERDGLRLAPEEALYLL
                     HRGRIEVPGHTFDSLLALFAARPNFMRSFLVYRDIRERGYAVQTGPHDFRVFRRGQKP
                     GRGPSQYSISVVSERDLIVFQKVIEEVTASRNIRKQHVLAAVDDENELTYYEVKIQVP
                     EGGMAGGTVPHLVGELVGRNAIVHTEGSRCPGGWGMQLDSDRLVLSPLEILCLLKSGN
                     LVLTGEGAGMDPDTFARTARESDVEFPEKMEVYEDLRKKGLVPRTGYKFGHHFRVYTG
                     RKIHSEMLVQALPGGAALPMSSISRSVRLAHSVKKKMLFACIHNGGIRYVEFARIKL"
     gene            105310..106566
                     /locus_tag="PK679_01430"
     CDS             105310..106566
                     /locus_tag="PK679_01430"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HPC54653.1"
                     /translation="METPINPWSSQQTDDIEKLFSLFGIEHISTIEGILPKVPSFISR
                     GVVVGHRDYRVIAEAIRDKRPFHILTGFMPSGHPHLGHLMVMKEVVWHVQQGGSGYIT
                     IADREAHAVRDISWQQCEHFGKEYLQCLFALGYRGRTYFQSRNNALKDLAFEAATRVN
                     FSELQAIYGFSDETSLAHAESVITQVADILFPQVDSYPAPTLVPVGIDQDPHIRLTRG
                     IAHKLRMFTVEERDGYISVRSKNAPEEALAEVHRKFPGSRKYQGHVDIPRAGCAEVSA
                     EVRKIEIAHGGYGFYTPSSTYHRFIPGLQGGKMSSSIPESTITFSEPDDVVRKKVMGA
                     FTGGRATLAEQKELGGEPEKCPVFLLNLFHMVDDDAELAEIHRRCRGGELMCGQCKKE
                     TTERVLAFIHDFREKMEASAHMVKVE"
     gene            106568..108028
                     /locus_tag="PK679_01435"
     CDS             106568..108028
                     /locus_tag="PK679_01435"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HPC54654.1"
                     /translation="MDLSPNEKRLLVLLEKVKTADPSALAAEMGVSPESVIQYAYLLA
                     DRGLCRVEKEVKTTYSLTEEGQRYASEGLPERQLLGSFNEKIPVQELTRHPLARIGIG
                     QMKRKGWVVVRGGMVEKTGKDAPGEDELALRDLSRGGPGLAELRRRNLVTENLETRYR
                     ISVTPEGLDWARRGLDMSEEAGTLTREQIVSGSWKGLKLRKYSLKAPPRKVYPGKIHP
                     YQRVIEEMRQILLCMGFTEIYGGIVQSAFWNFDALFQPQDHPAREMQDTFYLKETLPL
                     PEGYERVRDMHLFGGNTSSTGWGGRWSREKAEQCVLRTHTTCLSIQHLATHPEPPVKA
                     FCINRVYRREAIDPTHLPEFEQLEGIVMDRDVTFRHLLGFLKEFYHRMGFPGVRFRPG
                     YFPYTEPSVEPEVFVPSLGWVEMGGAGIFRQEVTAPFGITHPVLAWGLGVSRIAMLRL
                     GLSDLRLLYKSDIGWVRETPSWLHGPDTGVGGQKCR"
     gene            108019..109659
                     /gene="pheT"
                     /locus_tag="PK679_01440"
     CDS             108019..109659
                     /gene="pheT"
                     /locus_tag="PK679_01440"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HPC54655.1"
                     /translation="MPVIRLYYRYLEKLVGTDRETILANLPMIGSDIERVEEDHVDVE
                     FFPSRPDLFSVEGVARAMRGYLGIETGLPRYSVTPSGIEFSVDPGLATIRPYLGSAVI
                     RNVKLDEESILSLMGLQEALHWAVGRGRSKVAIGIHDLDAVTPPFRYIAAEKSRAFVP
                     LDFDREMTLDQILDEHPKGRAYAHIVSDFPRYPLIVDARDRVLSFPPIINGELTRVTQ
                     ETRNLLLDTTGTDERAVATAVNIICTALADTGATVQSVTIGGRECPSLAPSERIVSSD
                     DASALLGVPLDSTALSSLLEKMRYGAGPAGVSHVRVLIPCYRADIMHDWDIFEDAAIA
                     YGYGTFDAEMPRTFTVGAPHPVMAIYAVAREVMSGLGFQEVLPFTLTNERVLATKMQR
                     PLKDSVLRVMHPISEEQTVVRTDLLPLLLEMCQLNRHRELPQRLYAVGDVVGGTHTYP
                     RAACVSTHAAADFSEAYAVADAFCRELDVAVSVEESDDPAFIPGRRGNLVSGGKTVGV
                     FGEIHPAVLNAWELEHPVAAVEIDLTAVPGYPGQQGTP"
     gene            complement(109616..110422)
                     /gene="hisF"
                     /locus_tag="PK679_01445"
     CDS             complement(109616..110422)
                     /gene="hisF"
                     /locus_tag="PK679_01445"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HPC54656.1"
                     /translation="MTLTRRIIPCLDLKDGRVVKGTHFVGLRDAGDPVALAQRYNEQG
                     ADEVVFLDIAASVEARGTILDVITRAADQLFLPLTVGGGIRSVDDIQQILRAGADKVS
                     INTSAVNDPTLINRGADKFGTQCIVLAEDVRRNFTPNPDATMVALPDGRECWYEVVTY
                     GGSRPTGIDAVRWAIEAEERGAGEILLTSMETDGTKNGFDIPITAAISDAVGIPVIAS
                     GGVGTLEHFYEGFALGRADACLAASVFHYGEMTVRQVKEYLAARGIPVRL"
     gene            110555..111781
                     /locus_tag="PK679_01450"
     CDS             110555..111781
                     /locus_tag="PK679_01450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylhomocysteinase"
                     /protein_id="HPC54657.1"
                     /translation="METGKKKIAWARQYMPVLASIRGEFQQNKPLKGIRIGMALHVEA
                     KTACLVETLAAGGADVHITGCNPLSTQDDVARALDEVPGVHCYARRGVTAGEYYAAID
                     RVLDSHPQVVIDDGMDLIHRLHTVRRDLLPHVVGGCEETTTGVHRLRAMAREGKLAFP
                     VIAVNDTPMKRHFDNVHGTGESAIAGIMLTTNMLVAGKVVVVAGYGFCGRGLARKLHG
                     LGARVIVTEVDPRRALEAYMDGFSVMPMEEAAGAGEIFITATGNTSVIAEPHFARMKS
                     GVVLANAGHFNVEIDIGWLEKNATAVTRRDGIDTYTVDGKDIHVLAEGRLVNLAVPKG
                     MGHPIEVMDLSFSLQALCALHIARQGRTMNPGVHEVPPEIDETVAERKLASLGLSIDK
                     LTELQKSYLSGWESGT"
     gene            complement(111751..112656)
                     /locus_tag="PK679_01455"
     CDS             complement(111751..112656)
                     /locus_tag="PK679_01455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HPC54658.1"
                     /translation="MPSVILAKDQPFDLDLSLSCGQVFGWEREETAWRGIVGQKVIRI
                     VQKGDRLSFSGADTGFIRYYFALDVDLPEILSSIDRDPVIHYAVSSCSGLRIIRQPPW
                     ECLASFICATYSNIPGIRKRVHLLCQNLGAPLSPEYPGLFSFPSPTAIAGAETCMLSG
                     CSLGYRAGYLRETARVLAADTGWEERIDALSFPKARANLLRLKGVGKKVADCVLLFAF
                     GKWESFPVDVWIERIMTRCYPECRDLRTYDKISDFGRAYFGKYAGYAQEYLYCCRTVL
                     AGRVDAGKGRGGGSNLYVPDSQPER"
     gene            112790..113116
                     /locus_tag="PK679_01460"
     CDS             112790..113116
                     /locus_tag="PK679_01460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54659.1"
                     /translation="MELNEVLRAFLETGEDWERKNTSLNGVSIIKLPGTRTRPPSLAI
                     EINPVNQKGTPMKKKGVMIMNATELSAFRELFSNPKVDSLVRTIEEVAPGKKDQKGGA
                     GDVLVI"
     gene            113285..113770
                     /locus_tag="PK679_01465"
     CDS             113285..113770
                     /locus_tag="PK679_01465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54660.1"
                     /translation="MRSISLRFHAPGDIFAPLVILCILTLALALSAGCTDERGPRGPV
                     TEPPALLMDYSRTGGIAGFSDRMVIYSDGGVVYQTRQKSGAFTLDQENMERLKRLIRD
                     VEASGLNGTYPAPSQGADYFSYALVFGNRTIKTETTGVPEALSPLISFLDEILAANRD
                     T"
     gene            complement(113976..114869)
                     /gene="nifB"
                     /locus_tag="PK679_01470"
     CDS             complement(113976..114869)
                     /gene="nifB"
                     /locus_tag="PK679_01470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009399 - nitrogen fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase cofactor biosynthesis protein NifB"
                     /protein_id="HPC54661.1"
                     /translation="MTENEYKVADVGGKKVQWDPEQLRKIREHPCFSEKACHAFGRCH
                     LPVAPRCNIQCNYCIRDFDCVNESRPGVTTKVLSPREAVEMVRKAIEKYPYIKVIGIA
                     GPGEPLANEETFETLRLLHEEFPNVIKCISTNGLLLPDKIDLLHKYDVGNITVTLNAI
                     DPDIGAKIYQFVDYKGKRYEGREGAEILLKNQLEGIRMAVERKMIVKVNTVYIPGINE
                     DHIPEIAKKVGEMGVYTFNVIPLIAQYRFSHIAPPTPEMKRKMQDDCAKYVRQMRHCQ
                     RCRADAIGRLGQDVQSCLYSE"
     gene            115100..115654
                     /locus_tag="PK679_01475"
     CDS             115100..115654
                     /locus_tag="PK679_01475"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HPC54662.1"
                     /translation="MVPALSIAVIACIIVTGCTTIQPGTSQGAAIGDTVRVTYRMAFP
                     GGEPFESNENSTPLEFVLGSGVMIRGFDQAIVGMKPGETKTVIIPPELGYGQRDEKMV
                     GTVSTPLLKKILDDLEKNGTFTQIEFPGLNGVMYRYKLNDNRVVYYTFTNISPETTTV
                     DQNHPLAGHELEATITLLEITRKA"
     gene            complement(116279..116352)
                     /locus_tag="PK679_01480"
     tRNA            complement(116279..116352)
                     /locus_tag="PK679_01480"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(116316..116318),aa:Val,seq:tac)
     gene            complement(116458..>117108)
                     /locus_tag="PK679_01485"
     CDS             complement(116458..>117108)
                     /locus_tag="PK679_01485"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HPC54663.1"
                     /translation="MENRFRHAWDREYTRRGRIFGRITQDYPEILPGERFLDVGCGDC
                     RAFRALALAGGTGLSAISVGLDHSRPALSICRPLVSRMDNMHVVCADATLMPFPDETF
                     DTVFLIHVLGHALLDDRKRMVREAARVVRRDGRIYVRVFSLSDFRAGEGIEVEQGTYI
                     RKTGICTHFFSPGEIRDLFSPNEPVFLDTASWTMGTGNKKLYREEIHGMFLAGKRK"
BASE COUNT        25335 a        32895 c        34279 g        24499 t
ORIGIN      
        1 agagggcatg gccggatata cactttccca tgattgcgaa ggaaatcgca gtcatggctg
       61 atgaaatgct cgatttcacg gccatttccg tcctgatcaa tccattaaaa ccggaatagg
      121 ggacagactc aggtcccggt ctcctatgag atgaagaaaa gggaaaaaag tttatttcgg
      181 tcccaggtag ggattccgca gggccttgtt cacgccgaac ttcgcccttt cctcgacggt
      241 cttctggttc ttcgtgatct tctcggtcgc aagcttggtg acgagctcaa gaccgggttt
      301 cacctgctcg atgggcttgg tctcgaaaca cccggcagca atcgccttgc tccagatatc
      361 gtcaccgttg cgtgtccgga caaagaccgt gctccacccg tcggggctcc cgaccgaccc
      421 ggtcgagaca tcggcgaggt tggccacgta gtcgaggcag acgtggcatg cgggctgttc
      481 gtacttgtgg gtcaccttga gggggagctg gacgacctgc ccgcgctgcc catacaccca
      541 gaacttgccc ttgccgatct ccatcttctt gacggcctcc atcttcattg ccgcatggtc
      601 ctccacgagc tgcctgatgc tctggtagga gaagttctcc atgcagaata tgccgatggc
      661 gagcttgatc ttgtcgtcga cgtcacgcca tccgaccggg tagagctggc ctttccggac
      721 ggcctgcatc tggcacggtg tcccgacgat accgatcttg tcaaggccat agctcctcgt
      781 cgcttccttg atccacgaaa cctgggggct gatgttgtac ttcgtgcccc ccgcggtcat
      841 cagttcctcg acggtggtcg cgatgaacgg gcggggcctc cacggctcgt cgccgggtcc
      901 ggcaacgatg gcaccatcga tgataccctc ttcaagggcg aacttgaaga gctgggtcac
      961 aattcccccg tcctgggcct tcttgaggat ggccttgtca gtgctgcgag ccgatacgca
     1021 gagtttgtac tttccgagtt ctcctgccat ttctctcacc tcacttgagt gccgccccaa
     1081 tagcgtccat tatggcctcg aattcgggaa ccacgtcgaa gttgaagaaa ctcctcgggc
     1141 actgggcgta gcatgcaccg cacttgatgc acatctccct gttcacgttg ggtttcccgt
     1201 actcgtgggt aattgcccgg accgggcatg ccgccgcaca ggacccgcat cccatgcaga
     1261 gtccctggtt gacgacatcg atcatcaggt cacagccaca ggcctcggtc ccgcgctcgg
     1321 caagctgcat cagcggggcg aggtacttct ttgcaagctc ctgctggtcc ttgttgccct
     1381 tcaggagcag gtatgccatg acgcatacgt tcctgatcag ctgcgggcag ggggcacacc
     1441 cggggatgta gacatccacc ttgatcaggt ctccgatagg caggtatgac tcgtgctgcg
     1501 gctggttggg ctggccacca cgtgaaaacc gcgtgatgtt gccgtaacag gcacacccgc
     1561 cgactgccac cacgacagct gccttctcgc gggtctcctt gatctcctgt actgatagtt
     1621 tgtcctggat acacaccgac ccctcgacga gtgccacgtc catcttggga atgtgccgca
     1681 cgtcggcgag ggtcaggcca tagacaaggt cggcgtattt gtcaagaatg gttaacaatc
     1741 caccatagtt gtctgctagg gataccagac agcccgtgca cccgctcatg tgcacgtggc
     1801 caactgtaat cttgtctgcc acaggctttt cctccttttt tatcgtttca gccttcttct
     1861 ccacaccagc tgctgccgca ggttttgcct ccggcttctc gctggagctc ttctttccga
     1921 agattttcga gagtagtccc ataatccacc cctatcaggg ccagtacttc acgcactgcc
     1981 cggggaatcg ccgccattac ttcatccgag agtccgatct cgaattccgg tgcacttacg
     2041 cgccggggct ggcacccgat gactgtgatg tcgaccttat gcttcaacct gtgaagcggc
     2101 tcggtgagat cccacgagtg ggcatcgcga taactgcccg gcgggaggtc atcgacagag
     2161 aaccgcgcca gctggccggg ttttccaccg aagtccgcgg tatcgacaat gatgagtttc
     2221 cgtgtcactg ccggatcgag cagcgtaaaa atgaagtgcg ggcctccaag gcctgcatcc
     2281 acggctttta cattgtcggg aagatcgagg cgctggagct cctcaatcac tgcgggaccg
     2341 aacccgtcat cggcaaacag cgggttgcca caccctgcga tcacgatctc gggatacagc
     2401 atgccggaat tctcactgga tgagtttctg ggcgatgact ttcctgtcct cgtcgatgac
     2461 gatcatgtga gttgcacatg atacgcacgg gtcatatccg cggacaatca tttccgcaac
     2521 ctgccagggt gcaccggtca gggcacggct gcaggtcggg aagttccagg tggtggggac
     2581 cagcatctcg taatagagga cacgtccgtc cttgaccttc gcgaggtgga cgtccgtccc
     2641 acgcggggcc tcgtttgcag cccagccgag ggaaccgtca ccctgcggga tatgatctgc
     2701 aatgaccttg ccgctggggt tgtactcgtc aagggctttg aggatggtat ataagcagtc
     2761 tgtatactcc agctgccggg cgatgtgctg gccccacgtg cccttctcgt cgaagttctt
     2821 gaacgtgaca aggcgtgccc gcgggccgac ctcgacgggg gccccgtcat agagcggaac
     2881 acctgtgcat gcctccatct ggggattcac ctttgttccg acaggggacg tccctccgat
     2941 ggggtagctc gggtctgcaa ggctgacctc gccctccccc atgtaccagt cccacggcct
     3001 gacatcggtc cacctgttgg gatcccagcc ggggttctca tcaaggttgg tgcttgcata
     3061 catcgggtgg gcggccatga caccctggtt gtggtaaccc agtgtcttgg gaaggggaat
     3121 ctgtttcccg ccgacctcga cccagtctct ctttttcata ttgttgatga ttgcaagcat
     3181 gaattccatc tgctcgtggg caaggaccag accttccttg gcgaggtcgt acatctttgt
     3241 gaccgcctgc ttcgtgcagg ccttgtacat cccgccgaca cgggggttgc tcgggtgcac
     3301 ggcctctccg cccgcgatct cgccgatagt ctggccgatc tcgcgaagcc tctggatcct
     3361 ctttgccacc gaccggacag gttcctgggg ggagaacggg tttatcttgg tatccgtacc
     3421 cggcaggtaa aagtcaggca ggatcaggat gttgtggagt gcgatgctgt gcagccggtt
     3481 ggccgcctgc aggatgatgc ggagcagttt tgcatccttt gggatctcgc agcggatcga
     3541 gccttccatg gactcgatgc cggccagtgt gtgggcgatc gggcagatac cgcacacgcg
     3601 tgacgcgatc ttcgggacct ggtccatcgt ctttccaatg gcgagcttct ccacacccct
     3661 gacgggggtg atcgagagcc agtcaccacg ctcgacgata ccggcatcgt ctaccttcag
     3721 gacgagcttt gagtgtccct catgcctcgt ggttggagag atctctacaa ttttcgacaa
     3781 tataatcgcc tcatggtatt tctgtgttca cagtgcgata caggtgtttg ttccacactc
     3841 acctctctgt tggagagatg gttgaccgta caaagtacgt tcatcagaag tgtcaccttc
     3901 tcctattatt tatctcctct gcaaagttcc tgaactccca ggaaaacagg ttatgctgtg
     3961 aatgagacaa aaaagacgat aataaggagt ttttttggga tgccggtatg agaaaaatgg
     4021 tcaggaatag ggacaagcag tcctcggcca ggatccaaat caccgtttaa acgggttttt
     4081 gacggggtct ccatgcgctc gttctccagc cgtgtctctc aaagagaaag agtaattaaa
     4141 attccccttt cagcgaacca aaggtttttt atgtccatta agtatcggat gactccccgt
     4201 tcatctccac gaagagttct gccattgttg cctggcgctc tgcgtatgcg tcatgctggt
     4261 gaatactctc ctcgttcgtc tgcttgatgg tgacgaggga gtctccgggg agatcatgga
     4321 actcatggat gaccttcttg gcaatctcgc ggacgcagtc ttccacgaac cgggggttct
     4381 tgtgcgcatt gaggacgacg taactctcat cgctccgctt gagcagttcg aaaatcgagg
     4441 agctcatgga ctctttcagg atggtgatga tcttttccag tttcacgtgc tggtcgtcat
     4501 caatctcgat gcagaggaaa ccccttcccc tctggttgtg ggttgccatc gggacctcct
     4561 ggaggaagag ttcgattttt tcgtccggaa tgccgagtcc ctggaggaca gatattgctc
     4621 tctccttcat gatgtcctgg gcacacgggc aggccgtcat gcccgtcact tcggcaccga
     4681 tgctcttcct gacgatgggt tcgcggaacg tccgccgggc gaccgcacgc gcgtgaacct
     4741 ttacgacctc gtggcagtga gtccgggaaa tgggggtctc tctcttgacc atgaactggc
     4801 tgttcatgag gacctcggtc ctgtcggcgt attcgtggcg gtcgaggagc tttcgtgcaa
     4861 caacgctgca gaggttctcg atctccttga cttcaccgtc gattgcctgc tggaggacct
     4921 cgtcgatgac ctcgaagttg cgcgaaaggt ttgcaccctt gaggctcccg ggaagatcga
     4981 cgaagacgtc gaaattggag atgaatatga ccggcctctt ctccggacgg gagacctcga
     5041 cgagcttctt gacgtttttg accccgaccc tggtgaggtt gatacgcaca tccgggagcg
     5101 tggactggat atcgggcaaa tcacgcccgg atctgggttt tatggcattg ggaatagagc
     5161 atctctccca ggtctgatgt ggaatgtaat tttttcatat aatatttaag tgctctgtta
     5221 ccgatagatg tgagatcaga ccatgatgga aaaatactac gattccgatg cagacctcgg
     5281 ggttctctcg ggaaagaaga tcgctgtcat cgggtacggg tcccaggggc ggggacaggc
     5341 gctcaacttg agggacagcg gacttgacgt tgtgattggc ctgcggcccg ggcgttcgtg
     5401 gcaggcagcg acagcggacg ggttcaaggt cttccctgtc ccggaagccg tgaagatggc
     5461 ccaggtcatc cagatcctcg tgcccgacga gctccagggg gcgctctacc aggccgagat
     5521 ccgcccgcac ctttccggta agaagtgtct gatgttctct cacgggttca atatccattt
     5581 cggccagatt gttccgccac cggacgttga cgtggtcatg gtggcaccaa agggtcccgg
     5641 gcgcatggtc aggaagatgt acgaggaggg gaagggtgtc cccgccctca ttgccgtcca
     5701 ccagaactac acgggacagg cccagcagat agctcttgcg tatgccaaag gtatcggcgc
     5761 cacgcgtgcg gtcgtgctgg agacaacatt ccgcgaggag accgagacgg acctcttcgg
     5821 ggagcaggct gttctttgcg gaggaataac atcactcatc aaggcaggct tcgagacact
     5881 cgtcgatgcc gggtatgcac ccgagatggc gtacctcgag gtccttcacg agacgaagct
     5941 gattgtcgat ctcatctacg agggcggctt taccaggatg cgcaactcaa tcagcaacac
     6001 tgcccagtac ggggacctga cacggggtcc gcgggtgatc gggcccgaga cgtacatcgc
     6061 catgcaggag attctccggg agatccagac gggcgagttt gccaaggaat ggatgctcga
     6121 gaacatggtg aaccgaccgg tcttcaatgc cctcacaaaa gccgacgagg aacacttaat
     6181 cgagcaggtc gggaaggaag tgcgggcaat gatgccccag ttccagaata cggaaaagac
     6241 ctgattcttt ttttttaaat attgacgcgg gaaaaacgtc acagctgcat gcagcgggtg
     6301 agagaggaga gggcttctgc cacctctccc gcatcgagca cgagtttccc cgtctttcct
     6361 gtcacttcaa gcctctcccc accaagagtc cctatgaccc tgcaggggag gtcccggatg
     6421 tctttttcat ccctgaaggc gaggagaaac cgtccgtagg tttctgagaa gagcccggga
     6481 agaaggtcac aatcgagcgt aaccgtgcag cccggcgaga aagtcaccag tgccccaagg
     6541 agtcccccct gtgagatatc ggtcacggct atatcacgcg ttgtgcaaac ccgttcgcgg
     6601 acgagcggga ggaaccgggc actgcctaat ggaggcgcat cgcccccgca ccctgtcacc
     6661 gcatcgagga cggacccgcc gaaatgggcc cccggttccc cgagcagggc aagtccccac
     6721 ccctcccccg gccgggccgg ggtgaatagc ggcccttttc cgagcatgcc gatagacggt
     6781 gtgggcttta tccgcgtgtc gtgctcatcg ctttcgttgt aaagcgagac gtttccgccg
     6841 acaaccggtg tcgcgaggtt ccgggcagca tccccaagac ccctcacgca ctcggagagc
     6901 tgccagtata cttcagggtg gacggggctc gcgaagttga ggcagttgac gatgcagagg
     6961 ggagatgccc cgacacacgc gaggttcgat gcattctcga gcaccgcgtt ggcggtcccc
     7021 tcgtacggtt tgagatagat gtgccggggg ttgcacccgc aggagagggc gagtgcttca
     7081 ccatcgagcc ggaggacggc ggcatcaggg cctaaagaga cggtccggag ctggacatcg
     7141 tggtcgtatt gctcgaagac ccagtttttg aatgccactt ccgggtggga aaggaccttc
     7201 cgcgcaagcc ctgcaatgtc ctcggaaggc cgcgaaaaag gctttgaggc attgtatggc
     7261 cggctatccc acgtgcaggg cggtgctttc gtgacgagaa agtcaattgg aatatcgcag
     7321 acgacccgtc catggaacgt aacccggtat accggctcat cgatgacttc ccccacctcg
     7381 ctccaggaaa ggtcgtactt ctctgcaatc tgtcccatga gggggacatc gtccggttcc
     7441 acttcgagaa gcatcctctc ctgcgactcg gcgagcatga tctccacggg atgcatatct
     7501 ttctcccgct ggtgcacttt ctctgcccaa atgagacctc cgaacgtgct gcacatctcg
     7561 cttgaggcac ccgcaagccc ggcagccccg aggtcccggc aggagaggac ttttccggtg
     7621 gcggccatct ccagcaccgc ctcgatgagg agtttttccg tatacgggtc accgatctgc
     7681 acgctcggcc tgtcggaggc ctcggcgtct tcggagagat ctctggatgc aaacgacgcg
     7741 ccgccaaggc cgtcccttcc cgtcgatgaa ccgacgagga cgagcctgtt tcccggtttc
     7801 ttcacccgtg ctgtcaaaaa agagtccggg gctactgtcc cgatgcagac gacgttgacg
     7861 agcgggttgc cggaaaagtc cggatcgaag cagagatccc cccgcaccac aggcaccccg
     7921 atgcagttgc cgtaaccgcc tatcccggca acaacgtgtt caaacaggta cctgttcttc
     7981 tccctgtcga gcggtccgaa atagaggggg tccatgaggg cgatcggccg ggcacccatg
     8041 gagaggacgt cccggacaat tccccccacg cctgttgcag ccccatcgtg cgggtccacg
     8101 taactgggat ggttgtggct ctccatgccc actgcaagtg cagtccggtc attgaagcgg
     8161 acaatcgctg catcgtcccc gggaccgagg aggacaccgg gacccgttgt cgggagggtc
     8221 ttgaggagtg cgcgggtcga gcggtaactg cagtgttcgc tccagaggtt ttcaaagcag
     8281 gcgagttcca catcggtcgg ttcacgaccg agcctgtttc tgatctgttc gaggtcccgg
     8341 gcagatagca tgcaggaaaa ttttcatgct gaactcacaa aaagccagcg ggcatcctgc
     8401 gacggaggca tttttacccg ggcgcacaaa tagaaagaca atggtagacc cttacgagac
     8461 cctcctgaaa aaggcatatt cacacgtcac ggagccgaca gaagccagag aacgcttctc
     8521 tgtcccggaa gccaggtcct acatcgaggg caagacaaca gtcctcgaga actttgccga
     8581 gattgccgac accctccggc gggaccgtga ccacctgatg aagttcctcc tcggggaact
     8641 cgggactgcg ggtaaaatcg acggatcacg ggccatattc aacggaaagt tcgaacccgg
     8701 ccttattaac tccctcatca agtcctatac ggaggactac gtcatatgct cggagtgcgg
     8761 caagccggac acgcgccttg tcaaggacga ccgcgtcctc ctcctccgct gtgatgcgtg
     8821 tggaggacac aggcccgtga ggaagaggaa agcgcggacg gagccggtcg tcaacgaggt
     8881 gacagagggg gcgacacttg acgtggaggt ccagtccgtg agcaggaggg gcgatggcgt
     8941 cgtgaggatg ggtaagtata tcctctatat tccgggagga aaaccggggc agaaggtcaa
     9001 ggtcaggata acgagggtct caggttcgat cgtcttcacc gagaggctcc cgtcctgagt
     9061 aaagggcaac atcaccggga ggggaagaac cactcctttt ccggaaggaa aggagaatca
     9121 ttcaataaaa ggtcaggatt tcactttttt gattttttct tcgcggatgc attgaggctt
     9181 ccgaggaggt catcgcaggt tcgcgagatg cgctggcatg cttcggtgat tgcctggagg
     9241 gggtccttct tcccgttcgt ggtgaccaga agttccgggt cggagaactg gaacttgatg
     9301 agatacttgg caacatcaac gtccgggtcg gtcaggatct cctccgtaag gacgttcatg
     9361 aaggtgtgac cctctccctg gatgagaagt ttcactttgt ctttcgtcag ttcaaggatc
     9421 tttatattca tccacctatg aatgagaact ggaatcctat atagatatgg ttaaagggtg
     9481 ctcacggctg ccgggagggc agaggcaccg cttcagaaga caaactcctc gccgtcacgt
     9541 cccaggcggg ggaggtccaa gggcacgagg tggctgaggt ggacgcaccg gaagtcgcca
     9601 gcatggaggt cttctgcgag ttcgcaggct tcctcgtagt tcatgtgctt ggggacatgg
     9661 agcctgccgg ggaggagggc atcgacgagg agcaggtcaa cgccggtcag cgcctcccgt
     9721 gtccgatccg ggatgttcct gttcgtgtcg gacgtgtacc cgatacgcac gtctcctgcg
     9781 gatatgagga gaccgcaggt gtatgcaggg ggatggcaga caggaaggaa cgtccactcg
     9841 atgccatgga tgacgaacgg ttcgtactcc ccgaccctga ccggtggaaa atcgagaaaa
     9901 gaaaagattt ttccgcagta atccatgacg gggggcgggg cgaagaccgt cggcatcttc
     9961 tggacccggt agaactcacc aaaccccatg aaatggtcat aatggccatg ggtccagagg
    10021 accgcgtcaa tccggggcga cccgttttca aggagctggc ggcgcaggtc tggccccgtg
    10081 tcgacaagga tgttatggcc ggactccgag accagcaggg aggtccggag tctctccctg
    10141 ccggtttgcc tggcatgcga gcactgggga caggaacacc cgacccgtgg tgtcccgacg
    10201 gcatcacccg tccccaacag gacgattttc atcctcaggc cagccagttc tgggaccgga
    10261 tcgcgtttcg gttcttcacg gccgcgatac cgcgctcgat gtcagcaggc ccgatctctt
    10321 cccgccggtc catgagggca gagaggatgg cctccttgac catgatgcgc aggtcagcac
    10381 ccgagaaacc gtcggtcgca tcggccaggt ccgggaagtc acaggaacac ctgatacccg
    10441 ccgcgatctt ccggagtatc gcaaggcgca tgtccctgtc ggggagaccg aattccacga
    10501 cctcgtcgaa gcgccgccag gcagccccgt cgaggagctg ggggtggttc gttgccccga
    10561 tgaggagcac accgtggcgg atgaggctca cctggtcgat atttttgagg agagagttga
    10621 cagccctctt catggcacca tggtcgtcgg tgacccggct ctttgccacg aaatcgaatt
    10681 catcgatgaa gaggatgcag ggggaaaggc tctttgccag ttcaaagatg cgatcgatgt
    10741 tcttcgaggt ctccccgagg tactgggacg tgatcatcga taggcgcact tctatgacag
    10801 ggagatggag cttgcgcgag agtgcgaggg caagcgaagt ctttcccgtc cccggcggac
    10861 ccacgaagag gagttttcca acctcgtgga tgcggtgctt ccgcaacaga tccctgtgtg
    10921 tcctcgcaac ctggatcttc cggatgacgg tctcctgcgc gggggtgcat acgaggtccc
    10981 cgaagtcctg ttcgacttcc tcgggcgcac tgatgataac gagatcgagg gcacccttca
    11041 ggcgctcgtc gccggcaaga agtgttgcga tgcgcgactg gagaaacgcc cgcgtgtcct
    11101 cgaccggggg gttgttcgcg cgcacgtcct cgtaggagac attcgtcgat tcgaagtcgc
    11161 ggaaaaaata cgcaagtgcc gggttcttct gtatgatggg aagtcctcct tttttgagga
    11221 accaccgggc tgcaggttca agtgttgtca ccctgatgcg ctggccgaac tcctcgcagg
    11281 tgatgacagg ggtctcctgg agtttccggc acgcgtcggt gatgccaagg cccctccgga
    11341 tcatcccttc gctgacgtga acggggcgcc tgacatccac gctcccgttt atcccaaaga
    11401 tgattctgca ctcgggggtg agatcattgg cgtccagatc ggggcgcgta ttgaaaatct
    11461 cggcagtgag gacgatttcc atgagcttga ggatttcatc gtcaacaggc atgtctataa
    11521 cttaattcat ttcctgtgga attgtttaag agtatctcac cgggtcgtca cgatgcaccc
    11581 gtccccggtg acgatcaggg tatgctcggc ctgggatacc agtgaaccgg caacatctgc
    11641 gagcacggga tacctccgga gaactccatc cctcgcaagc gaggcgagtg ggatgtccgg
    11701 gcgggggtcc gagagccatc gtcgtgaaaa aggcatacct cttctttccc gcacttcatc
    11761 gagtatccgc cttgctgcag ggggccggac gggcctgacg gctacctgct ggaaaatttc
    11821 ggcccggggc ttctcactca cctggccgga ccctgtcgtt gcaaagggct cgattgcaaa
    11881 gaccagcccc tccttcagga ttgcgccccc ggggaacccg acgttcggga tattcggggg
    11941 tgtgtggatc atgtaccggg caagaccgtg acccgtgagg tttaccacag gacggaaacc
    12001 ccgcgactct atcgctttct ggattgcctt gccgagcgct cccgtcgtca ctccgggacg
    12061 gacgcattcg agcgcgcgtt cgagcccttc ccttgaggcc gcgataagcc cttcgtgatc
    12121 gcccaggtct actgtcgttg cgcagtcggc gatgtaccca tcgaggtgca caccgagatc
    12181 gatcttgaca acgtctcccg gctcaaagac cctctggtca ccccgtgaag cggtatcgtg
    12241 tgccgcatcc tcgttccgcg aaacgttgag gggaaatgca agccctgctc cggcgtcgat
    12301 caccatgccc tcgacctttt ccacgaggga gaggaggggg acaccgaccc tgatctcacg
    12361 ggcaccctgc gcgagtatcc ttgccgcgat tttcccggcc tcgatgtaaa ggtcaatttc
    12421 ctcgtctttc atctatattc ctcacaggac cagttccctt ttgaatcggg tgaaggaaga
    12481 aaatcccccg cgtttcacca cgcccgtgtt ctcgagccgg actcctcctg tacccggata
    12541 gtagaggccg ggttcgtttg tcaccacgct gttttctatc agttcctctc ccgacggccc
    12601 aagccccggc cgctcgtgga cttcgaggcc caccccgtgc ccgaggctgt ggatgaaacc
    12661 ccgcgacccg ctctcgtaac cggcatcgcg gaagaaatcg actatagcct ggtatacccc
    12721 ggccccggat atacccggtt tgatgagctt cgcggcaaga tcctgggcat cccgcaccgc
    12781 cccaaacatc tcggcaattt cgggaggggc ctcgccccgg cacacggtcc gcgtcatgtc
    12841 agaaaaatac ccggtcttct cgtgccgcgg aaagaaatcg atgacgatcg gttcaccttc
    12901 ccggagctgg ccgtcacccc tcctgtgggg catcgcggtc tcttcgccgc aggccacaat
    12961 tgtatcggac gggatacacc cgttttggac gaacacctgg tgaatggcgg aacggacaaa
    13021 agacgaggtg agaggtattg caccctggaa gaggagcccc tttcttgcct ttgcctttcg
    13081 gatcatgcgc agggcacggt ccatcgcgat gtcacagacg tgctggacgt cccgtatgca
    13141 ccttatttcc tgcgctttct tgacttcccg catgcgtgca aggaccccgc catcgatggc
    13201 aaccttcctc tcccgtgcaa gttccgaccc gagtgcatag ggcaaatggg gagggacaag
    13261 gagcgggccc tccacctggc gcccgatgac ccgggcgagc acgcgccacg ggttactctc
    13321 ttcctttgca acatcgaaaa aaccggcatc tgcacgggaa ataacagccg ttgtcgcctc
    13381 ttttgctgcc ctttcgcatt ccatctggga aacaacaatg aggccccttt cgcccggttt
    13441 cctgatatag aggatcggat ccgtcgtgga aaaacgggtc aggtagagga tgtttgcgtc
    13501 cccggaggtc ccgaacgcca cgtaagctcc aaaacctccc tcctttagtg cccggtcgag
    13561 cgcatccatg aatacaaaaa cgtgagacgc aatcccacaa gtacttttat ttcgaagctg
    13621 acattcctgt gatggacgcg gcgacaaggg agcagttcaa gtggaaattc tacaaactgg
    13681 ccataatcct caacggggtg gtgctgatgg ctgcactagg cgtcgtggtc tttttcaagg
    13741 cgcccggcac cctcaacatc cccctcgcag cactcttttt cgttcttgca gccgggctct
    13801 cccttttctt ccgcaggaaa tacaggctga cgaaggagtg gctcgatgcg cagtcttgat
    13861 ggaccgggat tcctgatccg gggggcgtct tcgtgatagg gagagtgagg gaagagatag
    13921 agctcatgca gcggcacgtg caggtactca gggcagtcgt ttcgaaccag ccaatcggga
    13981 tcatgaagct ctccgagctc cttgacctgc cttttcacag gatccggtac tcgctcagaa
    14041 tactggagca gttgggatac atccaggcgt cgccagcggg ggcggttgca acccccctga
    14101 gcgaggaact cctgcgggat cttgacgggg agatagatga tatgatcgcg ctcctcctcc
    14161 agatgaaaag ggaggggtgc ggtccggggg aagaaaaaac ggaaggagga caaaagccat
    14221 ccgctacctt taacaccgcc aagggcaacc tataaaggca taccaggcgt gccgccataa
    14281 ctcagttggt agagtggctg gctgttaacc agcatgtcac aggttcgagt cctgttggcg
    14341 gcgctttttt ctccaggggc ccgtagctta gtccggtcag agcgcccggc tcataaccgg
    14401 gcggtcatgc gttcaaatcg catcgggccc atgaaaaacc gcaatgatgg agtttttttc
    14461 ataccggtca gcgggtgaga ttccactcgt cccccggatt gccaaggtat gtatggtgag
    14521 ccgtgctatc tcggggtatg aagtgcccgg tgtgcggcag cgactgtatc gaggatgcag
    14581 gggtcgtcct cgggaggctg ccggatctct tttcaccctg tgaccagtgt tcctaccgcg
    14641 tccttgacaa gaacgccccg ctgtccgatg ggaagtatac ccctccctgc aggtgcggga
    14701 agcggttcat cgacgaagtc tatgcacacc tctacgtcat actcgtggag gagggagtct
    14761 tttccggaaa agagcccctc agggcagtgg gatcacccct gatccacccc ggggtcttca
    14821 cggccgcgcc acccttcctc ccggaagact cccttgttct cctttccccc cgcgtgacag
    14881 tgcctgttgc agagaggttt gtcgccgagg tcccggaaat ccgcggggtt gtcaggtcag
    14941 gcgatttcgt gccgggggcc gttgacccga ccctggagaa aagtccccgg acgtacgatc
    15001 tcctcgccgg ctgcgatgtg agggcgggaa tctttcctac gtctgcaggg cctctcgtca
    15061 tctacacgca gcagtccctg atacacatcg agtttccgcg cccccggaac ccgaagatcg
    15121 agtcggtgga gcgaaggctg aaggagggtc ttccggcagt ctttgtcgat gcctgtgcgg
    15181 ggaacgggac gctcggcctg tgtgcagccc tgcatggcgt ggggaaggtt atcctcaacg
    15241 atgcgtggta cgcggcagca tactggtcgg cgcagaacat tcatgtcaac cggaaagccc
    15301 tgaaggtaac aggcgttacg accacacttt catacgacga aatgaaggcc cgacaggtct
    15361 cgagggagcc tgtccttgtc gccgagacgg aaggggaaca ggatgtgtct gtgttttttg
    15421 gcgactaccg ggaactgtgg aaggttcttc ccccggggcc cgtctgcgcg gtcctcgatc
    15481 tcttcgataa atcggacatg gaagcaaaca ggcggattat gaaggagtgg cgggaccgtg
    15541 tccccggcga ggtatttatc ccataggccc ctatatcata cggggactag cccgggtggc
    15601 ccggcgtcac ctgtgacccg aaaccgtcgg tatgcggggg gcgaagttcg aagaaggcgg
    15661 aaccgggctg cctccgaacg gtacaggccg acgttgaaac ctcgtcccat gaggtcggtg
    15721 gacaggaacc aggaccccgg agggggtctg tggcctgctg tcgcggggac cggtccaggc
    15781 ccggaaggga gcagactcac cgtgaacatt cggcgcccat gggggtgcgg ggtggaggag
    15841 ggctgtgccg ggaaggggca gtttcgggcc gtcgaccgag aacgtgtccc cactttttac
    15901 caaagcggta ccttaccatg gcaaaagtga ccatcgttgg cgcaaccggc aatgtaggca
    15961 ctttctgtgc ccacacgatt ggacatatcc cttacgtgga tgagatcctt ctgcatggca
    16021 gggagggacg cgagaacctc ctcgccggga tcacgaggga cctttccgat tcctttgcag
    16081 cagcaggaaa ggctgtaaat ctctcatgga caacggatct tgccgatgcg cggaattccg
    16141 atatcgtcgt ctgcaccgcg ggagtcgccc gtaaacccgg tcaggaccgc ctcgaccttg
    16201 cgctcgaaaa tgcgcgtatc gtttcaaaga cggccgaagg tatcggtatc catgccccgg
    16261 acgcaatgat cctgatggtc acaaacccgg tggatgtcat gacatcggtt gccctccggt
    16321 attcccacat ggcgccccac cacgtatttg ggcttggcac gcaccttgac tccatgcggt
    16381 tgaagtccct gattgcccgt cacttcaggg tccacgtaag cgaagtccat acccgcatca
    16441 tcggggagca cggcgagtcg atggtgccgc tctggtctgc aaccacgata ggcggcatcc
    16501 agatttcgaa cctgccggcg ttcatcggcc tgcccgtcaa tgacatcatg ggagtcgtcc
    16561 ggtcaagcgg cgaggagatc atccggaaca agggggccac agtctatgga cccggggaag
    16621 ctatcgcaac ccttgtgcga acgatactgg ggaacgaaaa ccgtatcctg acggtctcgg
    16681 cctacatacg gagcgaggtc cacgatattg gtgacgtgtg catcggtgtc cccgcgagga
    16741 tgaacaggca gggggtcttt ccggttccga taaagatatc cgaggacgag gttgcccggt
    16801 tcagggaatc cgttgagaag atccggacga ttaccgcggc agtccttgaa aaattgaaaa
    16861 cccagtgatc ttttctctcc caaaaaaggg aaacgccagg agggggcttt gccttcgtca
    16921 ggtcagtgtg acttcagtga tctcggcccg ctcgaccccg gggattttct ggatcgcggc
    16981 ctcgactgca tcactttcgc ctgccgcatc gttcacgagc gctgcaacaa tgagggcttt
    17041 gagaccaaaa ccgatgggct cttcccggat gtccctgacg gccgggactt catttttaat
    17101 ccgatccttc agttttacaa gatcaacgtc aggcgattcc ggcatgacct tgagaatgac
    17161 tgcaacggtc cccatggttc acggccccgt aaacccgcac tttggacaga cataggggat
    17221 actctgttcc cggcagcgga aacatctcct gatctcgtac ccgcatttcg ggcaaccgaa
    17281 ctctgttgcg cccctttcgg caagtggcga attgcatgac gtacattttc tgactggcat
    17341 gaaacctcct cgcaaagtgt ctcatattat ctctcctgaa acacttaaaa gccgatggtc
    17401 gttccggtgg tcgccacgcc atcaagcaca gcagcgaggc gttcggggtg gaggccggag
    17461 atgaccatcg cgggtatacc gtgatcaagc acaaaaccca gaaaacaggg atcgacgtcg
    17521 tccgtccgga caggggaccg tatggcttgc tgcatcactc cctccgaacg gatgccgtcc
    17581 actgacttga ggaggaccag gggtacaccg agtatgtgcg cacaccacgc agcgatcgta
    17641 tccgacgtca cgtcccacga gtgcgggaga gggtcccgtg accggaggat ggagtagggg
    17701 aggagtatgc ggggcgtttc cggcatggcg agttcttcgg tgacggggat gccggaccgg
    17761 gaaaggtacc acccgtactg ttccattgca gaaacggcca tccagtgtgc ttccgttccc
    17821 actgcgcccg tctcgcgcac ggcctgtgca aagggtccgc cgccgggcac gacaaggaca
    17881 ggcctctctt tcctggcgag gagggagcat attccctcgg cgcgggaaaa gaggcttcca
    17941 ccgatcttga ggacgagggg aggggagatc acgccgggtt tcgtggatta atgtgagata
    18001 tttcagcaga ttaatggttt cctgccactc catccataga tcatgcactg gtgccgcctt
    18061 ttcctggcac tggccctcgt ttcacatgca accggcatcg ctctcgtcga gttctgccct
    18121 gacccgtacc tcccggagga ccgggacgag tatttctgcc tcgggggaag cggccccctc
    18181 gatggggtaa tggtcagcga tggcgagggg agtgtccggt tccctgcggg tgccgtcctt
    18241 gccggccgct gcgttgtcgc acgggatgcc ggggcctaca ggatgagcca cggcgagtac
    18301 ccggattacg agtgggatgg gacgacggca gaagtgccgg acatgatcag gacaggcagg
    18361 ttccagcttg cgaacacccg cgacgagatt accctctacc gggacagggt gcccctccag
    18421 agtgttgaat ggccggggat ggtcagcacg cgacaggggc aggtccacta ctgccaaaac
    18481 gggacatggg acccgcgtat cctgatgctc gggcagtctc agttccccga ggcgacgttt
    18541 caggatgcag atggccttgc cttcgtctca ccggactgct cccgggaggt tttcctctcc
    18601 cttgcaaggg gtgcccggac agaaatcctc gtcgcggtat acgagttcac cagccccgta
    18661 ctcgcaggcg cactcgtgga agccgcgggt cgcggggtca acgttacggt cctgctggaa
    18721 ggcgggccgg tgggaggaat ccccaaagag gagagatggg tgatctcccg gctcgaagac
    18781 gcaggcatcc cggtctacac catgtccggg acgccggacg tccatgcgcc ctaccggtac
    18841 atgcatgcca agtacatggt tattgaccgg tccagcgtcc tcgtcacgag cgaaaatttc
    18901 aaggagagcg gttttcctga aagggaaaag cggggtaaca ggggctttgg cgtggttgtc
    18961 acccatccgg gccttgcaga gtatttcctc tcggtctttt cccacgatgc cggcggaagg
    19021 ttctcgatca gggcaaaaac aggtgaaggg ccggaggaaa tgccctctca ggatgcatat
    19081 atgccgtctt ttgagccctg caggttttca ggagcaaccg tcacgcccgt gatagccccg
    19141 gatacgagca gcctggtccg tcggcttgtc cagggtgcag aaaggtccgt ggacatcgag
    19201 atggcataca tcacgaatga gtccgggtcg atgctcaacc cgttccttac cgatgcggtc
    19261 gatgctgccc gccggggagt ccgcgtcagg gtcctcctcg attcctatta ttacaacgtc
    19321 gagggcgaat cggacaacga cgaaatggtc gcaaccatca acagaattgc cactgcagag
    19381 ggcctgccac tcgaggcgcg gtgtgcggat atcggtcccg ggaaggtcga gaagatccat
    19441 aacaaaggtg ccattatcga tggcaggaaa gtcctcgtca gttccatcaa ctggaatacc
    19501 aactccccgg tgaacaacag ggaagctgcc ctgatagtgg aacatcccgg tgtcggggcg
    19561 tatttttcgt ctgtatttga gtcagactgg aaccgggccg gacaggaggg gatggcagct
    19621 cagggccccg atgtaataaa actcgttgct gcagtgctcg tggtggcagc catcatcata
    19681 ctcttcctgt acaggaagag aggccgttaa acaggatgcg agtgatcagt gaaaatcagg
    19741 agaccgttcc ctgatgcacc ggcagagatc gcagagagtg attgtgccac cgttgcctgc
    19801 aacagcctcc gcccaccggt cgagaaggat atccatgtcg ggtgacagct taaaaaaggt
    19861 accccccctc ttcttcttca tatactggga gactgcagcc ctgctcacac cgaggcgccg
    19921 cgctgcattg ctctggctga tcccccgctg ctgcacaagg cgacagacca tctctgcacg
    19981 caggcatggg agaatgcgcc tggccatcgt gtcgcagaac atgatgtcac agtcatgact
    20041 cttcatgcag tcaccgcgcg tggtcgggaa agatagatga cctgacgtgc gtcctcgaaa
    20101 ttgaactttt ctgcgatgag attctgttct tttaatttct tgagggcata ccggacagtt
    20161 cgcggagcaa gaccgctttt cttcacaatc tccttatgcg tcatcgcccc gttatcatcg
    20221 aggatgtgga gaacgatgag agacgagggt ggcaggtggc ccatgttcaa tcactgacaa
    20281 gtgttaacac tgttaacata aataaacaat gatggatggt ataagttacc cgacgtccaa
    20341 aatacaggac cgtgatactc gtccggcagg aaaagattgc actcgtgctc attctggttg
    20401 ttattgcagc agtcgccatc gccacattcg cccttgaatc tgccgggaaa ggagcgtttg
    20461 cacgacagat gggcccggat tcacgcgaag gagaccttgt ccttctcgag ggcagcgtgg
    20521 aagaagccag gatgactgca accgggggtc accagattct ccgggtggaa ggagtccggg
    20581 tctttgtccc ttcctcggcg gtcaggagcg ggtggcccag ggtcggtgat gaaatacggg
    20641 tttatggaac tgtccagacg taccgggggg agagggaggt gctcgtacac tctgcagggg
    20701 atatcacggc tgtggctccc cattcctgag aataccaatt gtatttctct aggagacatg
    20761 aacaaaaatg aaaaaagctg atacgacccg ttccttctga ccaattttaa tattaccgcg
    20821 gggagataaa gagagtggga gattttttag gatattgaag ggggaaagta tggagcagga
    20881 gcagagaaaa ttcaccgggg aaggcgggca caggatttgg atcctcgcag tccttggtct
    20941 cgtttgtatc gggcttgagg tcgttgtcca cctcaccttg aggacggctg tcggatacac
    21001 gcacattttt tacatcctcc ttgtcctgtc agcactctgg tatcaccata aagccctctt
    21061 catcgcagga ggacttgtct gtgcaacgct cgcgacgagt cttttcgtgg gagacctgac
    21121 atgggcaacc atcctccgcg ctgccatgtt cctcgtcatt acatggatcg ttgcaaccat
    21181 atcggacgaa agggaccgcg caaggagaat gctgcaggaa cagaaggagg aaattgagaa
    21241 gaagcactat gcactcgtcg gatacatctc cgaagcggcc ctcaggatga agaaccccct
    21301 cgaaatgctc cgggacaacc tgacatcgat gcgcgtccag cttgaccagg gacctgacat
    21361 cgaggagctg aagatgatgc tttcggtcca gatcactcac ctggaacaga tcatcgggaa
    21421 tttccgggag cttaaccggg aaatcgtcga ggaacgcgac gaaatccccg aagcgttccg
    21481 cgagttcctg acacggtgag ggaagatgga gacgcaattt gacattgggc gtctcggcca
    21541 ggaaaagctc ttcctggtac tttcatcagc cgaaaggctc aggcagaaca acattcgcgt
    21601 tataaagacc ctcatcggca gggggtacag ggtggtcgtc atcacaacca accagccctc
    21661 ggcaattctg aagaagcatt acgcagccga ggggatcgat atggggaaag tcacattcat
    21721 cgatgccatc acaaagtatg ccatcgggcg tatcccggaa ggagagaccg ataccaagtt
    21781 tgtcaacagc ccatcgaacc tgacggatct cggtatcgcc attacagagg ttctcaaccc
    21841 ggcatccgga gagaaaacgt gtctcctgtt cgattcgatc agcaccatgc tcatttatct
    21901 gccgtcaatt cacatttcaa agttcatcca tttcgtcacg agcaagctgc gactcctcga
    21961 tgttccgggg attttccttg cagtggagaa ggggattgac cccctcctcc tgacccagct
    22021 gacaacctat gtcgatgacg tgatcgatat ggacaaaccc ccgggtcttt tgggaccgga
    22081 tggcaaatcc cccggcacct gatttttttt cgggatatca ggcacctccc gttttcatga
    22141 tatggtatct taccttcccc tcctccacgc aggcgcggac catacgctcc cgggacgaga
    22201 gcgatgccga cctgccactc ttgacttcga caaagacgat ctcgtcgagg ctgccggcag
    22261 aaagacccga aaagaccacg aagtcaacgg gcgagccgag gaaccgggca tccctgggat
    22321 tatagggaaa gctgggaaag aaggggataa ggtgctcggt gaccctgccc ctgaccacgg
    22381 cttcgctcct ctcgactgcg tcccgcctta tccgggtttc ctgcgcggca acccactcgc
    22441 ggcagagcag ttcagcgcgt tccctggcct cccgctcgag agagacggat cgccattcct
    22501 caaagagggt gtgagccctc tcgtcaatcc tttcccgcgc gcgaaaatat gcaaggagca
    22561 gaatgagaag cgccagaatt gcagtaacca gcgcgaaagc aagcaccatg accgtgatct
    22621 caaccatgat caggaaaatg gattaacgac aggaaaatga ttccctgtcg aagaaaatgt
    22681 gacgtgatac cgatcaggga gaattaccct cgccgggagg cgagagcttt tttaaagcaa
    22741 gcaatacttc ctccctcact ctccggtcag ggtcgtttac cagtgccctg agtggctcag
    22801 cagccgaggg atcgccgagc acaccgaggg cccaggcggc atgcttccgg accagtgcct
    22861 tttcatcttt gagagcctcg atcagggcag gaacagcacg cctgtctcca aggcgaccga
    22921 gccctatcgc ggcacctatg cgcagccatt tctccgggga acgcaatgcc tggatgagtg
    22981 gttcaaacgc cctcccgtca ccgatctccc ccagggactt ggcagctatc cacgagacct
    23041 ccacgaaagg atcggaaaga gcttcaatca gtgcgggaac ggcagaacca tccccgatga
    23101 ccccaagttt ctcggcggct ttccaccgat cgtccaggta agggcttttg agaagaccaa
    23161 cgagccccct gacccgtttc cttcgcatag cctcctcggc ctcaattttc acgcggtccg
    23221 gcacttgcgt atcgggcatc cagattgtcc ccaagggcag gcatttgcga ctggtcatta
    23281 taagtgttgt ggaagggaaa atgccccctc aatcactgcc cggcggatat ccgggtgtac
    23341 agggtgaaaa agcactttcc aggagagaat tgatccggtt cccgtcacta ccgggttgtg
    23401 atttacacta tagcgtccag atccagcccg atatcgaggc tcttcgggct gtgggtgagt
    23461 gccccgatgc tgatgacgga gactccccgg attgcataat cggcgatatt atcttcattt
    23521 attctcccgg aaacttcgat gaggggaagc cgcgggagtt gggaatccat gagcacccgg
    23581 agagtctccc tgacaaccgg gggctccatg ttgtcgagga ggagtatatc ggcacccgcc
    23641 cgtgccgcac gaagtgccac ctccgggctc tcgacctcga cttctatctt ccggtagcag
    23701 gaatgggccc ttgcccgttc aattgccgtc tcgaggggga cgatggccag gtggttgtcc
    23761 ttgatcagga taccgtccga tagtgtcagg cggtgagggt caccaccccc gagaatgacg
    23821 gccttcttgt cgagcacacg aaggccggga catgtcttgc gggtcgatgc gatgcgtgcc
    23881 ccgggaagct tctggtcgag cacgtcctgg agactccgtg tcatcgttgc aatgccgctc
    23941 atccgtccca tgatgttgag tgccgttctc tcgaccagaa gaacggcttc ggccagtcct
    24001 tccacttctg caagcacgct gtccggcccg acccgatccc cgtcacgaac gaggggtcga
    24061 aagataacgt cacagaacaa aaaaagggcc tccgcctcct ccagcccggc aatgacgccg
    24121 ccttccctcg ctacgatccg acccctgcac cgctctcctg agaggacaga tcctgacgtg
    24181 atatctcctg cgggggcgtc ttctgcgagg aatgagagga gcatttccct tgggagatgg
    24241 aacggccccc tcactgccct gcctccagca tcctccgtat tgcacgccgg gccttctcca
    24301 tggtctcttg gggaaggatg acttcgtact gctcccgctc gagcgacagg agaaggtccc
    24361 ttgttgtaat cttcttcatg tccctgcaga cagcatcgtc tcttacgtgc acctcctggt
    24421 cagggtagag cgtccttaac ctgtaagcca tctccctttc cgtcaggatt gtccacctcc
    24481 tgccgggttg ctgcccccgg agcgcccgta ccattcctcc cgtcgaagcg acgaggtccg
    24541 ccatttcctg gatctccggg cggcattcgg ggtggcagat aaccgtatcc ccccgatccc
    24601 gtgcagaaac gacgtcctgt gtcgagaagc actggtgaac gtagcagtgg cctgccgggg
    24661 ggattgcaat gaccctcttt tccagcaccc gggactggac ataggcagca aggtttgcat
    24721 cgggggcaac gatgacctcg gttgcatcaa gggacctgac gacatcgaca gcatttgcag
    24781 aggtgcagac gatgtcagca agtgccttgc attccgccgt actgttgatg tagaggacga
    24841 ctgctgcacc ggggtgctcg gcccttgccc gcgcaagcat cgcaggggtc agctggtcgg
    24901 caagcgggca ctttgcatcc ctgacgggga tgagaacttt ccgttcgggg ttaaggatct
    24961 ttgctgtctc ggccatgaag aggaccccgc aaaaaacgat aacgggcttt tttgtcccct
    25021 cggccatccg cgcgagttcg aggctgtcac ccacgaaatc tgcaaggtcc tggatcccgg
    25081 gtctctggta gttatgggca agaacgagag catttttctc ttcttttaaa gcgcgtatcc
    25141 tctcttcgat cgtcatgttc cgaccaccag ggggctgtcg aggttccgca gcagggtgag
    25201 gatcgagagc gcggcaaggt aactggtcgc agggttgtcc gggctcggga cgttgctcac
    25261 cctgatgtag atctctccga agtctccttc tgcctcgatc tcgtggatat tccgcgtcac
    25321 ggaggggtca gcgtagagtt cgacatccgc gtcccgtccc gcggcaaggc tgagtgcaac
    25381 ggagacgttc acgttgcggg ggaactcctt gatgcattcg tgggccttcc cccggaaaac
    25441 cagctgccgg tccgtggcct gaattccaag ggattcggga ctctttgtcg tccgcaggag
    25501 gagacgccgg acaggggaga tctggcccac cttgaggttg tcaagacccg tcacggcgcc
    25561 gctcgggata aagatcctgc gtccgctctg ccgggctgtt gcaatgaggc cggagaggaa
    25621 aacggggtct gcaagtgccc ctaccgagag gaggatgaga tgttttccct ctgcaaggac
    25681 gcgctgcccg tactgccgtg cagcccgtac cgatgcggcc tcgactacat aatcgaagtc
    25741 agcgctgatg aacgaatcaa aatcgctgta cgccgttccc cctgaaatgt cagcgagctc
    25801 ctgcgccctt ggaaacacct ggtcatacag ggccagaatc tgacaatttt cccggttttt
    25861 cgcgatgata tgaccaatat tcccgcagcc cagaagcccg atccggatca ttgtacagac
    25921 ataatgaatt cttcgggtta agcattttcc tccacggaga agagatttcc aaaaagatgc
    25981 gggtttgaca tacgcgcctg ccctgcaggg aaacgaaagc agcaatggtt gacacccgca
    26041 gcaaaaaacc ttcaggaagt cgggaagaag ggtacttacc aggtatggaa cgcgacaatc
    26101 aaggagacga cggggggacc atgcgtccgg gatccgggct gcattttccg cttccgggaa
    26161 ccagggtcta catgcgcaca tatgggtgca cctacaacga gggtgacagc tggaaactcg
    26221 ccgagatcct caaggccagg ggatgtatcc tcgtctccga ccccttactc gctgatgcca
    26281 ttgtaatcaa tacctgtatt gtcgtcggga agacagaacg gaaaattctt cacgaactcc
    26341 gccagcatgc cggacgcccc ctctatgtca cgggctgcat gccgcttgtc caggcggatg
    26401 caatcaggaa cgtgtgtgac cctgtgatca tccaccccga cgacatccat gcagcttacg
    26461 ccgagctgaa gactgttccg cagggatccg taggggtcgt ccaggcatgc aggggctgcc
    26521 ttgggtcatg ctcctattgc gtcacgcacc tggcacgcgg aaagctggtc agcaggagcc
    26581 ttgaagatgt cacgcaggag gcagcccgcc tcgttgccgc cggtgcagtg gagctgagac
    26641 tcaccgggca ggacctgagt gcatggggga gggatacggg acagtctccg gctgatctcc
    26701 tccgttccct cgacgcccta tgcggccggt tcatgatacg tgcggggatg atgaaccctg
    26761 caacactttt tcccgtcatg gatgaggtcg cagaagcctt ccggctcccg aagatatttg
    26821 cagcgctcca cctccccatc cagtcagggg cagaaaaagt cctttcgagg atgcgaaggg
    26881 gatacacaca ggaacaggtc gtttccatcg tggagcggtt cgaaagggaa gtccctgccc
    26941 tctcgctgac aaccgatatc atctgcgggt atccgggcga aacaggggac gatttttccg
    27001 agactctggc actcctgcaa cgaatcaggc ccgaccgcgt cattgtcacg cggtattccc
    27061 cgcgtcccgg cacgcgtgcc tggcacgaga aggacatgcc tgatcgcatc aagaaggaga
    27121 ggtcacggac actccgcgtt tgtgccgagg agattgcgcg gcaaaagaat gccaggtgga
    27181 aaggccgggt cctccctgtc atgatcacgg agcacgtccg gcccggaacc tcgctcgggc
    27241 ggacacggga gtaccgcgct gttgttctgc agggaagcca tgaacccggg tctgtccttt
    27301 ccgtccgaat cctggaggat cgcacttact atttcaccgg tgaaccggtt tgattgtgga
    27361 aaccatgccc ggaagccccg tgttaccata tcgcgaaatg tggtttatta tcctccggag
    27421 gggccaaaag gaagcattat tgccggtgct gccgatccct tctgtgaaca ccccggaaga
    27481 acccctgcag cgtgcgggga agggggagac atgtcgggaa aagacgaaat tgaaaaggga
    27541 tacacgaaat tgctcgggaa gatcgaggaa tataacggga agatcgagga attaagcgaa
    27601 gaagtcaggt cccgtgacag tgccctgatg gaacggatgg gtgaactgac tgcccccctc
    27661 atcggcaaga tcggactgaa catgctcaag aggggaaagc aggacacaaa gggagaattg
    27721 tatgacacgt ctttttacaa ggagaagatg atagtcctcg ggaggaccga cccggtgccg
    27781 cacaggcccg atgatccggg aaagaaggtg gatgaccagt tctgcgtcct cggagaagac
    27841 ggccgtttct acgagctgat gtacagcacc gatggtgttg ttgtcgattc ctaccggaac
    27901 cctctttccg cgcaggatgc actgaaactc tacgggtatg acatcatggt catgctgtac
    27961 cgggcaatga gggattacct gcagggccag aaagaactcc tcgatgccct tgaaaaaacg
    28021 atcgcgttca tcacgcaggg aaaataggat agttcagggt tatttccatc caaagagggg
    28081 aaagaggggt ttgagaaggt cttcgtcctc gatatccccc ggcctgagga aaaaggtctt
    28141 tgagaaggct tccccctcct cgttccggta actgacattc actttgacct tgtcagtcac
    28201 gggaggaacg ggaaacgttg aggcctcatc ttccccgaga accggcagat cgaagtggag
    28261 atcctggggt tctagagata cccttacgga cagtgccttt gcattacccc tgttacgcac
    28321 cctgattccc tttgcattct cctcgatgaa cacaaagatg ttcggcttca tcacgctgtc
    28381 ctgcatgatg aagagggaca ttgccagtgc aatcacgagg actgctgcaa tcaggctggc
    28441 atagatatcg acaaggaaat agagtgcgac gcaggcgaag agtccgagca caaggacgat
    28501 gagcaggtct cttttcatac aatgcatgta acacgggatg gataataaga agatgggaaa
    28561 tgggcccgat gtgattcgaa cacatgacct cccggttatc agccgggcgc accacctggc
    28621 tatgctacgg gcccccgggg ttgccgtact acttaatcct cgctggcttt tataggtttt
    28681 gaattcctgt ctgccggggg actacgaaag ccactatatt aaatgtgggt ctgtcagaat
    28741 gtacgtgtgc gaatccctgg tgaataccca tgaaaaccca gtacctgctt ggcaacgagg
    28801 caattgccca cgggtgcctg gaggcacccg tcgattttgt gacgggatac ccgggtacac
    28861 cgtcctcgga ggttgtcgat atcctcaggg ccgttcccga ccgcggctat tacatcgagt
    28921 ggtctgtcaa cgagaaggtt gcgtttgaaa atgccctttc cgctgcatgg tgcggtctgc
    28981 gggcattatg caccatgaaa cacgtcggtc tcaacgttgc agccgatccc ctcatgacga
    29041 gtgcctatac gggtgtgacg ggaggactcg ttgtcatgag cgctgacgat ccttttgcac
    29101 acagttcgca gaacgagcag gacagccgtt gttacgctct tttctcccgc ctcccctgcc
    29161 tcgatccctc gggcatccag gaggcgcatg acatggtcag ggacgcgttt gcactctcgg
    29221 agcagttctc gctgcctgtc atattccgcc ccacgacccg tgtctgccat tcaaagggcg
    29281 ataccctgat cggagagccc gtcaggaata cgcggaaggg agagttccac aaggatcccc
    29341 ggcagtatgt cgtcatcccg gcccacaccc gcatcctcca taaaaagctg aatgagaaac
    29401 agcccgctct caagaaggca ctggttgaaa agggatacaa caccgccgtg atcaggggtc
    29461 gccgggcagt ggttgcaagc ggtattgcag ccgcctacgt ccaggagatc ctccctgacg
    29521 atgtctcgtt tatcaagatc ggcgcatatc cgattgacga agaatggctg gcagcccagg
    29581 tatcacgcca tgaaaaagtg cttgtcgtcg aagaactcca cccggtcgtc gaggaagcgg
    29641 tccggcaggt tgccgggaca atcccggtat ccggcaagaa gaacggggtc gtgccttacg
    29701 agggggagct ctccactgcc tcggtcgcag cgatcctgaa gtcctttggg atcaatccgg
    29761 gggaggagta tcctgccacg agtcccgttg cggatctccc gccgagaccg ccgatactct
    29821 gcgccgggtg catgcaccgg ccggttttct atgcaatgcg cagggtgttt cgggacggcg
    29881 tatatccaag cgatatcggg tgctatactc tcggcctcca gctcggtgcc gttgatacga
    29941 ccatatgcat gggcgcggcg gtgaccgttg caagcggcat tgcccatgcg ggagattcaa
    30001 gggacattgt tgcgacaatc ggggactcga cgtttctcca ttccgggata cccgggctcc
    30061 tcaatgctgt gtataacggt gcccggatga tcctgatcat tctggacaac cgcatcacgg
    30121 ccatgacagg tcatcagccc aatccctgtt ccggggtcac ggcctgcgga gggccgtcac
    30181 cccaggtgtc gctcgaggca ctttgcaggg cttgcggtgt atcgtgggtc gagaccgtgg
    30241 acccgtacga tctcgtctcc ctcatggcca ccctccgggc tgcaaaggac cagcccggtg
    30301 tcaaggtggt gattgcccgg cagccctgcg tgataatggc acggagagcc aacctcagga
    30361 gggggcgctt cgaggtcgat ccggcaacct gcaccgcctg cggcgtctgc atagggtttg
    30421 gctgcccggc catcgagaag agggatgaca aggcattcat cactgatctc tgcagcggtt
    30481 gcggggtctg cgcccagatc tgcccggcag gggcaatcag gaaggagacc aggacggagg
    30541 gaaagagatg agcacgagtt ttgatgtcct catggtcgga atcggtgggc aggggatcat
    30601 ccttgcctcc aatattctcg gggaggcatg ccttgccgaa ggaaggagtg tgaaaggagc
    30661 agagacacac gggatggcac agaggggagg atccgtcgag gggcatatcc gcattgatgg
    30721 aaagttcggt cccctgattc cgccgggttc ggcccgtgtc atcatcgcgt ttgacatgct
    30781 cgaggcactc cggtatgcac acttccttgc cccgggggga atgattgtct caaacagtca
    30841 tttcgtcatc ccgacgtcgg tctacatgca gggagttccc gttcccgatg agaaatcact
    30901 cagggagaga ctctctgcct ggcccctctg cctggtcgat gcagacggga ttgcggcaga
    30961 agcagggagt ttcctctccc agaacgtagt catgataggt gccgcgtcct ggtttttacc
    31021 cctgaaaccg gcatcccttc ttggcgcaat cgaaaggctg gttccgcaaa agacggtgga
    31081 gatcaaccgg aaggctttcg aacttggcag ggcagcagga gaaaaatgca ggacggagag
    31141 acaaggagcg tgaaggtccg ggacacaggc cctttttttc ctgatacaat ctaccagggg
    31201 gacgcacttg ctctcctgcc tgaaatcccg gcaggatccg tcgatctcat cgtgacagat
    31261 cccccgtttg cgatcgattt cagggccaaa aggacgaact ataacaggac cggttcccgt
    31321 gtcctggacg gttattgcga ggtcgccccc gatgaatacg gtgactttac caaccgctgg
    31381 atggaagagg cttttcgcgt cctctccccg acggggagcc tctatgtctt ttcgggatgg
    31441 aacaggctca aggaggtgct ctgcggcctc gatcgggcag ggtttcacac gatcaatcac
    31501 ctgatatgga agttccagtt cggggtgttc acccgccgcc ggtacgtcac gagccattac
    31561 catatcctct ttgccgtcaa ggaccccctg cgttacactt tcaacaagca ggaccattac
    31621 ccggaggatg tctggttcat ccggagggag tactggaagg gcaaaaagaa gactgcaacg
    31681 aaactcccgc gggaactcgt cagcaggata attgcgtatt cgagcaaccc gggagacctt
    31741 gttctcgatc ccttcatcgg atccgggacc gtcgccgtgg ttgccaggga aatgggcagg
    31801 cactttctcg gtttcgaggt ctccggtgaa tactacgcgt ttgcgctcga gaggctccgg
    31861 gaggagggca tgcacacggg gctgacctct gaaagagggg acgctgaggg ggagaattga
    31921 actcccgagg ggccgaggcc ccacaggctc tccaggcctg cgccgtaccg ctagactacc
    31981 tcagcaaaag gagtgcatcc atactatggg gcgggatttt ttttaatgct atctgattcc
    32041 cgggctatcc ctccggaggg gcacaggaca accattccgg cgggcctcgt gccatggtct
    32101 ggtctattcc ggggaatcaa acccgcctct ccttcttttt ccatcccggg gggtacgtcc
    32161 cccgcggaag aaagacgctt tccggtgcga taacgagtcc gggttttccg ggcgaaaact
    32221 gtgtcgatga gacaagtgcc tgccccgtgc agacgagttc ccctttctgt gtcatgactg
    32281 ccacgcgttc acccttcctg aagaccccgg acgagagaat accgactccc gcgagtgcgg
    32341 caccatggca gagtgcatcc acggcagagt cgcggatgac aacttccggc aggccggcga
    32401 gagcagattc gggcgggagg atcatctccc ggagggggcg gacacatccc atgcggaaag
    32461 catctgcggc atcgcgaagc ccggcgaggg tatgggcaga atcctcccgg aacgggccgg
    32521 agcgggtcct ccggagttcc tgcatgtgtg ccccgcatcc gagagcgagg cccatgtggt
    32581 ggcagagtga cctgatatac gtccctgcgt cgcagcagat gcgcagcacg gcaagccgcc
    32641 cgtcgagttc caggagatcg agggactgaa cggtccggat acggaggttc cttgcaacgg
    32701 aactcctccg ggggggcctc tggtagatac gcccgcaaaa ctcgctgcag gcctttctga
    32761 ttgcctcctc gccggggttg ccatggaatc gcaccagagc cacgtattcc ttgtcgtggg
    32821 agaggaggac gggtgcaagc ctgacggcac ggcccaccat cacgacaagg acacccgaaa
    32881 caccggggtc gagcgtgccg gcatgcccga cgttctgccc gaggatgtcg ccgacccatg
    32941 cggtcacctg gtgacttgaa ggtccccgtg gtttgtcgat gacgatcagg ccgccacgcg
    33001 ggacaggcac gggctcttca tttcccacta tggaaccctc ccggaagacc caagaaccct
    33061 gttgagggca gaaagcgtcc cctcgaggga tccgtctccc acgacgtgag gggggtgtcc
    33121 cccctgctcc atcgcgccgg ccgtaacctc accgatggca atcaggacaa ggttgggccg
    33181 tggtttccag acggctttcc ggtaggacat ggcactcgtg aagagcagac cgtcagcatc
    33241 atcgaggggg agaggaatcc cggttggttt cagggagtaa cagaggattt ccgtaacacg
    33301 tcccccggca gattctatcg aggcaataag accggggttc ggcacgtccg cgcgggggat
    33361 accgacatgt ttgcctgcta cccagtctcc gacgtaccgg gcgaaatccc ggctgtagaa
    33421 gctgtccagg acctcggagg atatgccgaa tttttcgagt tcacgttttg tctgaggtcc
    33481 gatggcgata acacgcggcc agcgctccag ttttggggca ataaggcggg cgggaagggc
    33541 actcgtgaaa aatatgcagt caaagtcccc tctgttaacc ctgcaggcga acacctctac
    33601 cgcttccctg tcgacaactg cctcgagagg ggagactgcg taacactcat gaccgaaggc
    33661 cgcacaccgg gccctgtcat cggttgcctt ttcccggagc ctcgttatcg caattcgcat
    33721 cccagaactc ccacgcaggc tgctggtctt ttgatctggt atcgattcct ttaagataat
    33781 tgcccccctc ccttggcagg gatgatggag ctgctcgccg ggacggcagc aggggttgtc
    33841 ctcggcaccg tctcaggact ccttccgggg atccatgtca acacactggc aggaatcatg
    33901 gtcgcgctcc ttgccctcct cctgccgctg tttggtcccg ttttccttgc tgcagtactg
    33961 gtttcggcgc tcataacaca ttgtttcctg gacgctgtgc ccagtacgtt tctcggcatt
    34021 cccgatgcag acacggcagt tgcagtcctg cccgcccatt ccctgtgcct ggaaggcagg
    34081 ggggaggaag cagtccgggt tgccgccctg ggcagtgctg caggggtggt cctttccatt
    34141 ccgctctgcc tgatcctcat cgtcctcatg ccgtccatcc agcctgcaat tgactgggtg
    34201 agcggaatcg ttatcctcgc ggtgatcacc atcctcgcgc tgcattcctc tgctgcccgc
    34261 gtgtctatcg cagtcttcct tgtttccggt cttctcggta ttttttcgtt ccgctatgct
    34321 ttcctgtccc cctcaccatt cggcgggagt gctgttctca tgccgctcct ctctggtctc
    34381 ttcggggtct ccgtcctcct tttctcgggc aggggggcag ttccgccgca gaatttttcc
    34441 ggcatcgccc tcgaaaacag gggaatcgtg cgcggatcga tcctcggaac catcgcgggc
    34501 gtcttcgtcg gatggctgcc gggcctctcg aacgcgactg caaacggtgt cctcgcttcc
    34561 gccgttgact attcacggga ccggcgggaa tatatccttg ccacgagcgc ggcaaacacc
    34621 acgaacgcgc tggtggggct tgccgctttc ttctcgatcg agaggacgag aaacggggtc
    34681 gtgtctgctc tttccgccct cgaggttcct tcactctcct gtcttgtcct ctctgccacg
    34741 attgcggcac ttgctgctta tattctcact gttgccctcg cgggcatggc gcaacgcatg
    34801 gagggaatcg acaggacccg gatggccgca gtcgtcatcg ggttcgtgat tctcgttgca
    34861 ttcctcacaa cagggccgtt cggactcctt gtcctcgctc ttgcaacggc ggtcgggtgc
    34921 gttccccggc tgcttggaat cccccaggtc ttctgcatgg ggtcgatcat gctccccgtc
    34981 ctgttcttct cttttggtat cggtgcattc tgatccgatc gtcaggcggt ttccccgtga
    35041 tgatccgggg aaggaacagg tgggtatatg actcctggta agcccagatc tctttcaatg
    35101 ccatcgtact ggtttggcga tgtcaccggc ggaaagtgca cgccggcagg atcccatgac
    35161 ccggaatacc tttcctttcg cctggacggg attcggactg aaatggaatc attctgtccc
    35221 cccgcatggg aggccgcgag ggactccggg tttgtctctt cgcgcgggga gtacatccgg
    35281 gtgctccgcg aggtctgcat ttaccgcgca gaaaaggccc tcgccctcgt tgcggcaagg
    35341 ccggaacagg aactgatcca gatggtccac atgcgggacc agctggacga ggtgattaac
    35401 cttgtcaccg gacgggcact ggagtggcat gccgccaggt cccctgaatt ctcgcggaaa
    35461 ttccgtgccc tgaagggaaa aagagcgctc gaggctcttg tcgcgggggg aagcccccgc
    35521 gtcaggggta ttgcaaccgg aatgatgcac ctgtcggagg taaaggctga tctcacccgg
    35581 gagatcgagc agatggcagg cgaagtgatt cccaactgca ccgggctcgt cgggggagtt
    35641 gtggcggcac gtctcctggc cgctgcgggt ggccttgaag cccttgcgcg cctccctgca
    35701 ggcacgatcc aggtactggg tgcccggacg gccctgtttg cacacatcag gtcggggtct
    35761 gcccctccga agcacggtat catctaccag taccggaagg tccatggtgc caaaaagggg
    35821 cggaagggaa aagtctcccg gacacttgcg gcaaaaattg cccttgctgc cagaattgat
    35881 tatttccggg gtgagaggga cgaggaattc ctggatacag cacgcgccgc agtggagagg
    35941 gcggcaggag agtccggctc atgatctgga tcgatggtgt cctcgtttcc cggggagagg
    36001 gaggagttta cggggaacgc atgatgcggg gccacagagt ctgggatccc taccggagca
    36061 agcttgcggc atactattac ctcggagggg aagtcagcct cgaatcacgg atgcgggtcc
    36121 tttaccttgg cgctgcccac gggacaacgg tttcgcacgt ttcagactct acggaggtcg
    36181 tttacgcggt ggaaaacgcc tatgccccga tgcgggacct ccttgccgtt gcgtcgcgca
    36241 ggaaaaacat catacccctc tttgccgatg cggcacagcc ctcttcctat gcgccactcg
    36301 tggaagaagt agacctgctc ttccaggatg tcgcacatcc cgaccaggca agtatcgcac
    36361 tcatgaacct cccgttcctc cggcggggag gggtcgccct catcgtcgtg aaagcccgca
    36421 gtattgacgt cacgaaaaaa ccagccgacg ttgtgcacga agtatcgcac aagctggcag
    36481 aatccggcct ttatccaaga agggtcatct ggcttgaacc ctaccaccgt gaccatgcga
    36541 tcctcgaatg cccgagggat tgagggagag tgtgattttc cgggttttcc aaaaaaagca
    36601 aaaaaaaatg gatttatagc ccggagcaga ttcgaactgc tgtcgcgaga tccagagtct
    36661 cgcatgattg accgctacac taccgggctg agataccctg atctattcac cctgtctctt
    36721 aattaacctg actggttttt atgcacgctg ccggggttat ccgggagccg gtcaccggca
    36781 tttcccgcag gagcggcaga cttccgggat gggggaaatg acctcgcctt tcctgcagaa
    36841 tggctcgatg tccgcggcat cgcgaatata gtagatatgt ggcacgaggg agacgtgggt
    36901 gtatgatccg cagccaagcc cgagtttccc ggcgatgtgt ttctggagcg acacgagggc
    36961 aaacatgttt gcacccgccg cagtgagcat gtcgttgctt cgaaatacca ctttcatgtg
    37021 gaggagacca ccccgggcaa ggcactggac gagctgcagg caggggcagt caccaaggga
    37081 ctggtccctg accgggttcc acgtgattgc gatggcccgc cgtgtcgagg ggttttcctg
    37141 gatcttgcgg agaatgtacg cgacctggtc agagtggatt tcagaccctt cccgggaata
    37201 gagcccctcg ccccagttga agaggcggtc gtggtagtca tactcaaaga cagacccggt
    37261 gccggagatg aggtcacggg catactgctc catgaaccgc ccggagaaac gcgaggacgg
    37321 gctcaccatg gggggtgtat ccggttgttc gaccctgatg gcgacctcct ctgactccac
    37381 ggttgcttcc ccgttctcgg tcgtgagggg tgttcccttc tcgaggacca tcttgacgac
    37441 ctgttcatgg gcagaggcaa gggtatgggc tctgatacac cgcatgctcc aatatgggga
    37501 aggcatatgt cgttaaagta atgttttccg ttcccccctc gttttttctg gttatagtgg
    37561 tggatggcag gcagcattag gactagagtt cgaaaggtca ggtggtccaa ctcactacaa
    37621 ttaacccatt ccaccaatct cttgaaacca ttcaaaattc gataaaattc actagaatgt
    37681 ataatctata tattgctgta ctaataagtg gtgtgcgcgt atgcgtggct atcggatgaa
    37741 taagggagaa tggggtgccc gccagaaccc ggtgaataac cggacaccaa acaggaaaaa
    37801 aagtgaaaat gctgaccaat ttcgggatta aacggttttt tccccttctc ttctccatct
    37861 cccgaccaaa aaggatatat gaggcgttcc acaaatattc aatcatattc cgttattcgg
    37921 agtatggagc acgggagaac cggcgttcgg catctgtcga tggcggttct tgcgtgtgca
    37981 tggattgaac gttcaggatt tggacatgag taaggaggac aaaagaatga ttaagcgctt
    38041 tagccttgca ctgattgcag tggtcgtact ggccgcactt atgctgccgg catccgccgc
    38101 aactatcaag caggtcccgc aaggcggaga tgtgttcatt ggtgaagagg gtcttgatgt
    38161 atccgcggca atcggaacag caacccaggt tgcctggttc gcatcaggaa atgaccccgc
    38221 cacctcgaca ccagactacg tgctgactgt cggaactccg accagcttct acgtctcccc
    38281 gcagaccttt gtgggtaaga ccgggaactg gtacaggtgg acaggtgcta tcggccccgt
    38341 tgcattcaac gtggttgacc ctgccatcgt cgtgaaggtc tgggacaaca ccgccggcaa
    38401 ggacgtttcc ggcaagtctg ttccgccggg caactatctc aacttcagga tcgagaccaa
    38461 tacctactcg gttactgcga gaggagatgc cggcacgcag ggattcgtga aggtccgcgt
    38521 gaagacatcc gatggtgcag tctatacgtc tctcttcgag acaacatccg catcctatcc
    38581 catcgataac ctcaggccca ccagtgacct ctggtactgg agacccaacc cgccagccga
    38641 cgggcaggga tggaacaccg gcgtccttga tgcaaacggc gcccggatgt acaaggcagg
    38701 cacctacaca gtgtatgccg agcttgacct gaacaagatc aaggacaact acaaggcacc
    38761 cgacggcagc gactacaccg gcaagacgat ctcctcgacc cagacggtga ccatcaccgc
    38821 cgacaccgtg aagatcgagg ccagcaagga cgtcgttgtc cgtggcaatg cattctcagt
    38881 caccattacc ggaaggccca acaccgagta ctacctctgg gtgaagggaa ccggccagat
    38941 gagtggtgaa tccctcgacc agccgccact cctcgttgaa agccagaagg atgtcacgaa
    39001 cgacccggaa ggtggcccgt acacaatcgg cagctaccag tacgagggtg gagcagggcg
    39061 caccatcaag gaggatgtcc cggcagcccc gagcaatggt gtctattact acgccaaggt
    39121 caagacctcc aactcaggca ccgtcactgt cggatggcag acttcccagg ccaccaagga
    39181 caagaagtac accttccgtg tcgagcgctt cgatggcagt gcctacaagt ctgacgaagt
    39241 ggatgtcaag gtcgagaagg gaaccgtgac cgttgtcgca gccggcgacc agagttactt
    39301 cctcggacag gaggtcaagc tctccggtac gaactccgag actgacaccg tgtacctctt
    39361 catcacaggt ccgaacctcc cctcacaggg tggcaaactg accgaaccga ggacaggcgt
    39421 tgtcaatgga aacgcgggaa cctttaccac agctgatgtc ctggacgaca acacatggga
    39481 gtacaagtgg cagactgcca acctgaacat cgacgcaggt acctacaccg tctatgcagt
    39541 cgcaactccg tccgacaaga acaaccttgc cgacacccag tacgcaaccg tctccatcat
    39601 catcaggaag ccgttcgtga ccgcggtcgc atcccagtcc acgatcgcgc agggtgacaa
    39661 gttctacatc cggggcgttg cagagggcca gccctcacag ggagtggcag tctggatact
    39721 gggcaagaac tacgtcctgt attcgaccga gagcgtcaac aacgacggaa gcttcgaaaa
    39781 ggaagtcaac cagggaatca ctagtaacat ggcggcaggc cagtacttcg tggtcgtcca
    39841 gcacccgatg tacaatgatc aacttgatgt cacccccgat aactccaata acccggtatt
    39901 cgtgatcggg ccctacccga cagccggatc caagatcttc aagctccagg gagcaggcag
    39961 cctgcaggga tctgacgctg cagaggcact cgttaccgcg ctcgacaact cctacgttga
    40021 cgacacctac accaagctcc agttcctgat tgaagcaccg gtcatccgga tctccccgat
    40081 caccgagaag gcagttggcg agaagttcga gatcacaggc accaccaacc tggccgtcga
    40141 tgacgagatc ctggttgaag tcgtctcctc gtccttcaag gcaaccaaga agaccgagag
    40201 cggagagttc agcggtgcaa ccggaacggt caaggtcaag aagggaacag agggctacaa
    40261 cacatggtcc ttcccggttg acacggccaa cttcaagccc gatgagtaca tcgtgcaggc
    40321 atccggtgtg actgttgacg tcaccacaac ggcactcttc aatgtcgttg agaagccgcc
    40381 gacaaccata ccgaccacca cgccgcccac gaccccgccg acgaccgttg tgcccacagt
    40441 gccgacaacc ccgaccccga ccccgacccc gacatcaccg ggattcggtg ccctggtggc
    40501 ccttgtcggc cttggtgcag tggcgttcct catcgtgcgc aggcactaaa agaacatcca
    40561 aaaccctcac ttttttctcg aaccctgcct ccggcaggat acagtgattc atttatacct
    40621 ttctgcccgg acacaaaacc actattagtc cggagggcgg aatttaagga agaagagatc
    40681 cttctccggc cgggcgggtc aggggccttc ggcacaggga aaaaggtttt gattctgcgg
    40741 gagacgggga taatgaagct tacagtcaaa ctgatggaca tcgggacgcg ggaagtcctc
    40801 ctgcacacgg aagatgccgg aaatatcggg gtcatgcccg gggaccgcgt ccagattctc
    40861 aatgaaggaa gtggtgttac agtcgcagct ttcgttgaca cgacaacatc gctcctgccg
    40921 aaagggacga tcgggattta ccggatcacc aacgaacggc tgcaggtcac tgacgggagt
    40981 gcggtcgagg tgaggagggc ggaaaggccc gtaacgctgg atttcatccg gaagaagatg
    41041 gatggcgagc acctttcgaa ggaggagaca tacgcgataa tcagggatgt cgtcgaggac
    41101 aacctctcgg ctgcggaact gacagcttac atcacggcct gctatatcaa cgagatggac
    41161 atggacgagg tggaacacct cacccgggct atggtcgata cgggtgagag actgcgcttc
    41221 cacacccacc cgatcgtgga caagcattcc atcggcgggg ttccgggcaa caagatctcg
    41281 ctcctggttg tgcccatcat cgctgcgagc ggcctgaaga tacccaagac cagttcccgc
    41341 gccataaccg gggccggggg aacggcggac ttgatggaag tcctcgcccc ggtcaacttt
    41401 tctgccgcag aagtccagca gatgaccgag aaagtgggag gagcgatcgt ctggggcggg
    41461 gcgaccaata ttgcaccagc cgacgacaag atcatcatcc aggaatatcc cttccggatc
    41521 gatgcaaggg gccagatgct tgcaagtgtc atggccaaga agtttgcagt cggtgccgac
    41581 ctcgccgtga tcgatatccc tgtcggaacc catgcaaagg taaagacagt ccaggatggg
    41641 aggagactcg cccgcgagtt catcgagctt ggagaccgcc tgaagataca ggtggaatgc
    41701 gcgataacat acggtgattc tcccgttggg cgggcaatcg gcccgaaact ggaggtcatc
    41761 gaggctctcc gtattctcga gggtgcaggg agtcccggat cgctcctgca aaagagcgtg
    41821 tcaatcgccg gtatggccct cgagatgtcg ggcaaggcag caaggtggaa aggagcggag
    41881 atggctgcag agattgtgaa gaagggtgat gcgctgaaga agctccgcca gatcatcgag
    41941 atccagggtg gagatcccaa cgtgaaatca gacgatatag aaccgggaag gcaccagttc
    42001 gtcgtcaatg ctcctgcgac agggtacgtg atcgagctca acaacaaggc attaatcagc
    42061 cttgcccgca ccgccggtgc accgcatgac aagggtgcag gcctcctcct ccatgcaaag
    42121 aaaggcaacc gcgtcgaaaa aggggagcca atctttacga tatatgcaga gagaagctgg
    42181 aggctccaga aagcgataga ggagggacgg cagctcatgc ctgtggtcgt cgaggggatg
    42241 ctcctcgacc gtgtcccgca ggacacgcgc tggacgtaaa tgaaggcata ccaaacaggt
    42301 tttattctct tcatcaacgt ccccctcttt tcccagggat atgtgaatgt ggtggcatcg
    42361 gggcaatcaa acggaaaaga gcctccggat ttgaccctgc ctgccatgac aggaggaaag
    42421 aagagcggac ccagcgggaa tcgaacccgc gtccttgggt ccgaagccca agaggatgtc
    42481 ctctacccca tggatccgga agaggcgttg ggaggacaac atattaagca ttttctgcgg
    42541 aaataatctc taaccatgat cctttctgca tccgagatca ggaggcgcat cgggcctgac
    42601 agccgggagg gcttccttgt catcgatcct tacagcgagg agtgtcagca gcccgcatcc
    42661 tatgacctgc gggtcggcgg ggactttatc ctgcctccgg cagtgtgcac gctcgtcaat
    42721 accctcgaga gagtcgaact gccacgggac attgcggcaa ctctccggtg caggtcgaca
    42781 ttcgggagga tgggagtgat actcacggca ggctttgttg accccggttt caggggccag
    42841 ctcaccctct gcctcgtgaa catgggacgt gaacacctga ctctcaggaa aaatgacagg
    42901 gtggcccaga tcatcttttt ccaggtcacg gacggcgaaa agggatacga tggcaggtac
    42961 caggacagca tgggagtcat acaggcgaga tgaatgatcc gcacagagag aaagtacatc
    43021 gagattctcc gcatattgaa ggaacacacg gaaccgatgg gtgcaaagag gctctcggaa
    43081 ctgatggccg agaggggttt tgtcctgagt gaccgggcag tccagtacta cctccgatac
    43141 ctcgacgaga tggggtttac gaaaaaggtc gggaacatgg ggagggtact gacaccctat
    43201 ggccacgagg agacggaaaa cgccctcgtc ggagaccgcg tgggtttcat catctccaaa
    43261 ctggaacgtc ttgcctacag gtgttccttc aaccccggga cctccaccgg cgacgtggcc
    43321 tataacctct ccatcgtacc ggaggagagg cttgccgatg caacggccgc attcgacgag
    43381 atagttgcaa aaaaatgggg ctttttttcc gggtaccggg tcatcgataa cgacccgagg
    43441 atcccccatg gaagtgccgg tattctgagc atctgcagca tcaccatgga tggtgtgttc
    43501 cgcagggaag ggatccctgt ccggatggca tatggaggcc ggcttgccat gcagcatgac
    43561 gaggctaccc acttcgtgga cctgataggg taccggggga caacgataga ccccctccag
    43621 ctcttcatct cctcgggact gacatcactg tcctcccttg tctcgaccgg ctcggggact
    43681 gcacttgcaa acgtccgcga gattccggcc cttgccgaga acagggcccg cgagatcgtt
    43741 gcacgaatga agaaagccgg gttttcattt cccgttgcca tgggaagctc ggtgttcaac
    43801 ctcgtcctgg acccctacag gctggcactc gtggcatatt cgggaatgaa ccttgtggcc
    43861 aacgcatacg aaaagaaggt cccgatacgg acagaaatcg gagcggggac aatccctttt
    43921 tcacggatta tccaggacta aacttttttc gttccgtttt cttcctccaa acactccctt
    43981 gtcctgcgca attccccgat gcggggcagg gtttccatcc ccgcaaggat gacgaggacg
    44041 ccgaggtatc tcgtctcctt cacggggtaa tcgccggaac ggagttcgag gccctggata
    44101 ctcctgtcaa gccacctccg taccgtcatg aaccctttca tgctcatctc gtggctcgga
    44161 cccgcgatga ggacgagggc cttttttacc tgggaaaggt cggtgtcggc tgaaatctcc
    44221 tggaacaccg ccctttttgc aaggtcgacg acccgtgacg ctttcacatg gcattccctg
    44281 acagaacggg tgtgcggacc gaaacggaga atatggtcca gcgggcgggc aggagggagt
    44341 tcctccctgg cataccctat tgtcaggagg cccatcccct ggatggtatt gaggatctcc
    44401 ccggcatcga gcacgacttc cgggaggttg tccggctccc gcatggaaca ttcgccggcc
    44461 cggagcagga gcgatagtct cctggcgatg agagtatcca tcgcctcatg aaagggatcg
    44521 acgggtttcc ttggaatgtc aggacgtaac ttttcgagca gttttccggc aatggcatct
    44581 gcatccatcg ctgtttcagg ttcggtgatt gcggggacct tctctttcca tgcctcatta
    44641 tcaaagacaa tgatcccgtc aagcgttgcg aggagcatat ccagctggtc aagagcacga
    44701 gcaaggcaga ggtctccctc gcttccccgg ggcagtgtac ataacccaaa taccggttcc
    44761 acgagggatt ttttcaggaa agaaacgaga tccggggcaa acgaggcatg ggtaccccca
    44821 agtccgcagc agagtaccag tgcatcgata tcaccatcgt ccattgcctg gaggtgagaa
    44881 aggatctcct cctttggaag gtgtgccgct atatcgtcag gttgagaggg atcgagcggg
    44941 gaaaagaaga gacggcggtc ggcaggtacc atctcaagcg acgcaagctc atctgcatca
    45001 ctatccgcgg cgagtccttc gacgcagtgt attgcactca tcctgtcatg ctcaagcagt
    45061 ttgtcgatga tacgcgagcc cgccccgcca agaccgattg caagaatgcg catgattgcc
    45121 ttcttctgtt cctgtgagtt ttttttcctg ttacgataaa gcacttctgt ttccgcaata
    45181 accgttctcc cccgtgtatc agggcggatt ggagaaaaaa atccaatttt tgaatcccaa
    45241 ggtcaattca ggtgctgcag gatctatgcg ggccactgca ggaaggcccg cacattcaat
    45301 ccctccaatg aaaagaccag tgcgtttttc cccggaggat gcaggatttt caggaactga
    45361 accccaatat ttgttatttt aacatgagcc ggtgattagc caaaggtttg gggaaaagaa
    45421 aatcataacg tatttaaatc ttcgttcgat actattccat gaggtgaatg gaaccttgac
    45481 aacctatgga atagagttcg taccaggcgc agtcaatgtc aagcaggtcg tgaactactg
    45541 caaactcgca gagtccaaag acattgacta tgcatggatt accaaccact acaacaaccg
    45601 ccactgctac cccacccttg ccatgatcgc ggcaaacacc acgacgctca agatgggtcc
    45661 gggtatcatg aacgccttta ccgacacgcc tgcagcaatg gcctcttttg tctgcactct
    45721 caacgagata tctgacggcc gtgcagtgct cggtatcggc cccggggacc tctccacgct
    45781 gcccaagctt gccatcaacc cggtcaagcc ggtcgcaagg ctcaacgagg cagtaaccca
    45841 gatccgcagg cttgttgcgg gtgaagaggt caagaagtcc ggcatggagt tctttgacta
    45901 tgatggcgcc aagctcaccg gtgtcaccct gccgggcaag aagggaatcc cgatctacat
    45961 cggtgcccag ggaccgaaag tcctcgaact tgccggaacg gtcggtgacg gtgccctgat
    46021 caacgcctcg aacccgaagg actttgccgt tgcaatcccg atcatcaagg cagcctgtga
    46081 caaggtcggc aagaagaact ttgatgtcgg tgcctacact gcgatgtcca tcgacatgaa
    46141 cgagaagaag gcccgcaatg cggccaagat agtggctgca tttatcgctg cagggtctcc
    46201 tcccgagctg atccagcgcc acggcctcga tgcgaacaag gtggcaacca tcaaggcagc
    46261 cctggccaag ttcgacttca agactgccgg ggagaacgtt gacgacaaga tcatcgacgc
    46321 attcaccatc gcagggaccc cggacaccgt caagcagaag tgcgaggacc ttgcaaaggc
    46381 tggtgtcacc cagatcatct tcgggtcacc tcttggcccg gacatgacca attcgatccg
    46441 gctgctcggc aagtacattg tgtaggcacc ccttttcaag gggataaaac ccacttattt
    46501 ttccatccgg aggcccagga gaggccaggg acccaatgtt taccatcacc gaggtcaggt
    46561 ccggaagcac cagaatccag ttccgggaag aacacgtctc cggactccgc tgcaagatat
    46621 ctcccgcgag gttgaaccgc aggctggatg cagcatacgt tcctcctccc gttccggcgc
    46681 ggtgcccgtt ctgcgaggga gaggtggaga gggtaacgcc gaccttttcc aacgggacac
    46741 gcatttccgt cggcgagagc ctgacattcc cgaacctctt cccgtttgcc gaatggcaca
    46801 ccgtcacgat cataacccgt gcccacagtg tcgacgggtt ttctccccgg cagatagaag
    46861 atgcgctgac gggacaggtg cagtcactcg gtggccagtc cggttacccg agcatcaact
    46921 ggaattacct tccctcggca ggggcgagta ttgcgcaccc ccacctccag gggctggtgg
    46981 acaggaggcc ggccgtcctt gccgaacggt acatggaggg tggattccgt ttcctgataa
    47041 ggcacggaga aaattactgg gacaggctca tcgagcacga acgcaacagc gagcggtttc
    47101 tcttcgggga cgagatcagc tggatggccc aggccgttcc cctcggcgag cgggaagtca
    47161 gggcggtcct gccggtatca acgatgcctg attttgagcc ctacatcggc acttttgtca
    47221 aagggctcct ctcggtcctg cgcatgtacc gcagcctcgg tacacacgct ttcaacatgt
    47281 cactcttttt tgacagcagg aagacggaaa acggttttcg cgggttttgt tctgttatct
    47341 cgcgaattaa cccgaacgtt tcctcgacaa gtgattctgc gttcatggag cggattcacc
    47401 aggaacccgt gatactcacg ctccccgagg aactcgggca ttattacagg aaaggctgaa
    47461 gaaaaggata cgccggatga ttacccggat atcctgccgg gtcatgaaac gccacgtaaa
    47521 caaaaaaagt ttttgggttt actcgggttt gctgatgagc ttggtcttcg agacgatgac
    47581 gccgtccttc ttgtggggtt tgcggacaac accgtcgcag gccttctcaa gctccctggc
    47641 ctcgtcacag agtgcagcag cgatccgcat catctcgtgc gcggaacaga caatcgggat
    47701 gtacttctcc cactcctttg tcatgaaaca gcccttgacg ttgaccattg cgacagactg
    47761 ggcaatctcg taggctgcgc gggccttggc cattgcatac gggttcgtga attctccctc
    47821 gacagccttg tcagaggtga ccacgagctt gggcagtacg agttctgcac ccttcttccc
    47881 ggccttgacc tggtcgatga tctggtccag ggccgtctgg agcttgcgga aagcacctgt
    47941 gacggagagg accttgatca ggttaccatt gtaatccgcc atctcgatgg ggtcgaggaa
    48001 ctccctgcgt gccccgatca tggcgtctcc cttcatgatg atatacccga acttgccgtc
    48061 cttgatctcg gcccattcct tctttgtcgt cacgtcatcg gtgatgaaga ccgtcgggat
    48121 accggcagct gccagtctct cgcgggcacc ggtgggtccg ggaaggacgc cgtttggaga
    48181 gacaacgatg gcaaagtcag gtttccaggc aatcatgttg ttgacgaccc ggtcaatgtc
    48241 ctcgggctgg agtttcgtcc cgctcgtggc catgaatgtc tgcatgtcct cacggtcagc
    48301 tctctcatcg aggaggagct cggccatcac accactcgcg atattgccca gcttagcaac
    48361 tcctactttc acaaccatgt aattcacctc ttttttgggt tataacaggt tactatctgc
    48421 cggtactgtt ataaacgttt tgaaatcttt tttcccccaa atcagcctta ttttcctgat
    48481 tttggtgcac ctcaaaagag aacatatctc ccggggacgt tacgtctcct caccagtttt
    48541 tccccaaaag ttaacgaaaa gtgtttaaat acgtcaggca ataccgttca tcatgaagga
    48601 cagtctgctg acagaccggc agaaggaagt cctgcgatac aggaaacagg ggctcacaca
    48661 acagcagata gcagatctca tcaaaacctc gaaggccaac gtgtgcacca tcgagaagtc
    48721 tgcaatggag aatatcagga gggcaaagga gacgctggaa ttcctctaca ctctcgatgc
    48781 cacacacctc tgcaccatcc cgggagggac ggacctgctc gaggttgcat cgctcattta
    48841 ccacgaagca gagaaactcg ggatcaaggt caggtatgat acgatcgccc tcatcaataa
    48901 aatccgcgaa gcagcacctg aacgttttaa agcccgtttt gtgaaagaga atatagacgt
    48961 ttatatcaca gaagagggag atctctattt cagctgaccg tttctacgtt cccggttgaa
    49021 caaggtttat atctttttct ctcgaattat tatggaagcc tatatgaggg ttatctgtcc
    49081 ccggtatgca gtccgcgggg cagagacctc atgagaggtc agggacacgg gttccaggaa
    49141 cgcgtgtctt tgcgtgagaa tgtggtgaat ggtcaccacc ggctgacagg gtgtcactga
    49201 aacaggcatg cagggtggac gaatcccctg ggatacgggc ccgtcatctg cccataaaaa
    49261 gaggcaggtg catgccggat tcaggatctc tttgcgagac aggtcacagg gagacggtca
    49321 ctaaccagga acagggccgt ctttttggag tactgcacct ggagggggat aacccactcc
    49381 atactgctga cggagggata gacgggtgcc tggacatcta tccatcgccc cttccccctc
    49441 cgcatgacag gagcccggac acgtcacaca tctccggtat gctctggccg aagataggcg
    49501 aaaaaaccgg aaataccggt aaaggccaca aggagtggcc tgcgacacaa tgcaagtgca
    49561 ggattgattg aaacatgccc aaaataaacc agccacgaaa aggatccctg gctttttcac
    49621 cccggaaaag ggcgaagagc ccggtacccc ggtaccagtc atggccctcg taccaggggg
    49681 accccgtgct gcagggcttt gccggctaca aggtgggtat gacccacgtg atcatggtgg
    49741 atgaccacaa gaacagcccg acagagggca aggatattat ggtcccggtc accgttgtcg
    49801 agatcccccc catgaaggtg gccgccatcc gggcttacag cagggacacc tacggcaggc
    49861 accccctcac ggaagtgtgg gccggcgagc ttgacaaggc actcgggaaa cggatcacac
    49921 tccccaagga atacgacttt tccggggcaa tggaggcact caaggatgcc attgcaaaag
    49981 gggtggctga agagatcttt gccgtgatgc acaccctgcc cgggcaggtc agtggtgttc
    50041 ccaagaaagt cccggagatc atggagatcc gggtcgccgg cgggactgtt cagcagcggt
    50101 tcgagttcat cgcgggactc cttggaaagg aagtccacct taaaaatatc atccagccgg
    50161 gtgcctatgc cgatatcact gcagtcacaa ccggcaaggg gacgcagggt ccggtgaaac
    50221 gctggggaat aaagctgcgc aagaggaaac acgcgcgggg aggcaagaaa aggcatgtcg
    50281 gcaacctcgg gccgtggaac ccccaccatg tgcgatggca ggttccccag atgggccaga
    50341 tggggtttca gcagcggacg gagttcaaca agagaatact caagatcggc gagaatggtg
    50401 acgagatctg tcctgcagga ggattcctgc actatggggt gctgagaaac ccgtacgtcc
    50461 ttatcaaggg gtcaatcccg ggaccggtca agaggcttgt ccgtatccgc cctgccatga
    50521 ggcagggtga acacgtcgtc cgtcagccgg ccatcgagtt cgtgagcacg gagagcaaac
    50581 aggggtgaag cagggatgaa agcacaggta ttatcgctgg atggttcggt gttgcgcgag
    50641 atagagctcc ccagagtttt cgaggaggag taccggccgg acctcattaa aaaggctgtt
    50701 attgccctgc agagcacccg gcgccagccc cacggaacct acccctatgc agggatactc
    50761 tcgtcagccc acagctgggg ttcagggcgc ggtgttgccc aggtgccccg catcaaggga
    50821 ggttcccggg cagcaaaggt gccccaggcg aaaggtggaa gggaagccca cccgccggtc
    50881 gtcgaaaagg tgctcgtccg caggatcaac aagaaagaga aacagaaagc attctggtca
    50941 gcactcgcag caacagtcag cgaggagatt gtccgggcac ggggacacgt cttttccgcg
    51001 aaggtcccca tcatcctcga agaccgtttc gaagacctca agaagacgag cgaggtcatc
    51061 ccggtccttg cagccgcggg cgtccttggg gacatcgaga aggcaaaggt cagccggaaa
    51121 gtccgtgcag gccgcggcaa gatgaggggc aggcgataca agcagaagaa gagcctcctc
    51181 atcgtgaccg ggaaaaagcc ccttgcagcc gcagggaacc tcgcgggagt cgacgtcgcg
    51241 accgtggacc agctcaattg cgaactcctt gcaccgggca cactcccggg gcggctcact
    51301 gtctggacag agagtgcaat tgcacggctc ggaggtgaac agtaaccatg gtgctccgtt
    51361 acccgtatgt cacggaaaag gccatgatga tgctcgagaa ccagaacaag ctccagttca
    51421 tcgtcgacaa aaacgcgacg aagaaagaga taaagcggga gatcgagcgc gccttcgagc
    51481 aggaagtcac cgacgtgtcc acgatgatga caatggacgg caaaaagaag gcagtgatca
    51541 gttttgcaaa cgagaaagcg gccgaggaga tactgtcccg gctgggtatc atgtaggtgg
    51601 ggaatatggg acatcgcata accacgcaga gccggggaaa aggagggccg acataccgtg
    51661 ccccctccca caggtataag gccgcgcttc ggcacgtgaa cagcaccggc ggacttgtcc
    51721 gcggggtcgt cgtggatatc gagcacgatc ccgcacgcaa tgctccactc gcacttgtcc
    51781 gcctcgagaa cgggacgaag gtttccatcc ttgccacgga aggcatgggt gtgggagacc
    51841 aggttgcatg gggagagggt gccgaggtaa agaacggaaa tacgctcccc ctcgcgcaga
    51901 tccctgcagg aacgttcata tgtaacatcg aggcccagcc caacgacggg ggtaagtttg
    51961 tccggtcagg cggggtccag gcggtcgtcg tcgacaggac agaggaccgc gtcggcgtga
    52021 ccatgccgag cggaaagacg aaatggttca gcagccgctg ccgcgcgact gtgggtattg
    52081 tcgccggtgg cgggcgcggt gagaaaccgt ttgtcaaggc cgggaagaag taccacaaga
    52141 tgaagaacac tgcatccaac tggccaaggg tgcggggcgt tgcgatgaac gtgatcgatc
    52201 acccgttcgg tggtggtgga caccagcacg ccggcaggcc aaagaccgtg ggccgcggga
    52261 ctcccccggg ccgggctgtc ggccacattg cagcgaggag aacagggctt tccaagaagt
    52321 gagtgatagc atatggcaaa gaagacacag aagagacttc ccaggcgtcg cgaagaattc
    52381 acgtatcgcg ggttccgcct ggacgacctg cgggcaatgg gcaggtccga gctgctcccg
    52441 gtcatgccat cgcgtgcccg gcggaagctg gtgcgcggcc tcacgcgcgg ggaagaacac
    52501 ctcctcaccc agttcaggaa aggggaaccg gtcatccgga cccacctgcg cgacatggtc
    52561 atcatgcccg agatggtcgg acggacaatc gaggtccata acgggaaaga gttcgtgaag
    52621 gtcgagatca tgcccgaggc cctcttccat tacctgggcg agttcgccct gacacggaag
    52681 aaggtgactc acgggagtgc cggtatcggg gcaacccggt cgagcaagta cgtgccgctg
    52741 aagtgatgga catggcaagg acactctatt cccggtcttt cgaaggcgac acatatgccc
    52801 ggggcaaggt caacgagatc caggtctctc ccaaacacgc aatggaaatt gcctccttca
    52861 tccgtaacaa gcggatatcg gaggtcatcc cctacctcca gcaggtcatc gaggggaaaa
    52921 aggctatccc gttccgcagg ttcaaccgga aagttgccca taagaggggg ctctccggct
    52981 gggatgccgg caggtttcca aagaaagcgt cgagggcata catccggctc ctcaactcgg
    53041 tcatcaagaa cgccgagtac ctcggactcg ataccgagaa cctcgaaatt gtgcatgcag
    53101 cagcaaaccg cggtcgtgca ttccgcggta tctttccaag ggcaatgggc cgggccacgc
    53161 ccaagcgcag ggagaccgtg aacatcgaga tagtggtcag ggaagtgcag taatggcagt
    53221 agagaggaaa ttcgtgtccg agggagcgcg gcgggcacgc gttgaaaagc acctcaagaa
    53281 ggagctcaag cgggcaggct acgggggaat ggatctccag aggactcccc ttggaaccca
    53341 ggtcaccatt tttgccgaga aacccggtat cgtcatcggg aaaggcggga aactcgtccg
    53401 ccagctcacg caggacctcg ccaccgactt tgcagtcgag tccccccaga tcgaggtcca
    53461 gcaggtcccg aacccgaact tcaacgccca gatcatggct gaacgcctgg ccaacgccct
    53521 cgagagaggg tggtacttca ggaaggccgg gcagagcatc atccgcaggg tgatggatgc
    53581 cggcgcactc ggatgcgagg tcattatcgc aggaaagctc accggagcac gggcaagggt
    53641 ccagaagttc accgagggat acatcaagca ctcgggcgag cctgtcaaca cgatcgtcga
    53701 gaaggggtac gccgtcgcgg tcaagaagct cggagtcatc ggggtccagg tcaagatcat
    53761 ccccgccggt gccaagattc ccgatcactt cgaagtcacg gcaaaaaggg agaaacccga
    53821 gaagaaaggt atcgagatac cggttgtcag tgtcggtgaa gacctcgcag aggacgacat
    53881 ccctgtggag cccgacgagt ttgacgagga agaactgctg aggaggaaat gaaatggcca
    53941 tattccgtgc aagggacgtg aagcagctct cggacgtcga gctctccgag cagatggaga
    54001 agctgaaaat cgagctcatc cagcattacg gcaaggtcag cgccgggggt tcgacagaga
    54061 acccgggccg gatcagggag ctccgccgga cgattgcccg gatgaagacc gaacagaaca
    54121 ccaggagacg cagcgtttca tgatcctgcc gcggaacatc ctccggcacg agttaatcgg
    54181 gctggaggtc ctggtgaccg gggccagtaa ccccgcactg catggcctgt cgggccggat
    54241 tatcgatgag accaggaaca cactggtgat ccggggggac catgggacaa agagggtcca
    54301 gaaagccggg acccggttcc gggtcaccct tccggatggt gtcctggtgg agatagacgg
    54361 ctccgcgctg gtcatggcac cagaaaagcg gatcaacgca attcagaaga caagagggaa
    54421 ataatggcaa ggaacatcgg attgagcgtc aggcctcccg agagggaatg caatgacgcg
    54481 ttctgtccgt ttcacggcac tttaccggtg cgcggccagg tgatcaccgg taaagtcgtg
    54541 agcgaccgga tgacagggac agtggtggtg gagcgggcat acctgcacta cgtgggcaaa
    54601 tacaaccgct acgaaaagcg gaacagcaag atacatgccc acaacccacc ctgcattcag
    54661 gcgaagaccg gtgataccgt gcgcatcgct gagtgcaggc cgctctccaa gaccaccact
    54721 tacgtcgtgg tggaggtgca gccatcatga aggcaaagca gtcgaacatt ccacgcgcac
    54781 tctcgaccgg gacgcgactc ctgtgcgctg acaacaccgg tgcgcgggag gtgcagatcg
    54841 tatccgtctt cggctaccat ggtgtgcgga gacgccagcc gaaaatggga ctgggcgata
    54901 tcgcgaccgt gagcgtaaag aaaggtacgc ccgacatgcg ccgcaagctc gtcagggcag
    54961 tcgtaatccg gcagaagaag gagttacgga ggccaaacgg catgcgtgtc agtttcgagg
    55021 ataacgcagt ggtcgtggtg gatgacaaga acgaaccgaa ggggaccgag atcaaggggc
    55081 cgatcgcgcg cgaagtggcg gagcggttcc ccaagatcgg ttccatggcc accatcatcg
    55141 tgtgaggcag atccatggtc cgagtcgaga gcaaacaacc aaggaagcag agaaaagcac
    55201 ggtatgcggc acctgcccac gcgaggaacc acttcctccg ggcgccgctc gcacctgccc
    55261 tgagggaaca gtaccacagg cgcagtatgc gggtcgtggt gggcgatacc gtcaaagtcc
    55321 tccgcgggga gtcggcagga acagaagggc tcgtggacat ggtggacacg aaaaggtcca
    55381 cgatcgtggt ccagggagtc tctgtcaaca aggcagatgg aaccgaagtc ccacgaccca
    55441 tcccaccctc gaacgtgcag ataaccaggc tgaacctgaa agacccaaag agggcagaga
    55501 aactgggagg ggctgaataa tgggagacca tttgaagagg ctcaatgccc ctgattcctg
    55561 gcacgttgcc aagaagacga gcaagttcat cgccaagaca tcccccggcc cgcacaacgc
    55621 caacgcaatg cctgttgcag tctggctccg ggaccacatg caccttgcgg tgaacgcaaa
    55681 ggaagtcagg cagatcctcc agcagaagga ggtcatcatc aatggcaggc catgccggaa
    55741 tccccggatg ggtatcggga tctttgacat catttcaata ccacggatcg gcaggcactt
    55801 ccgtattctt cgggacaaga aggggcggca caagacgatc gagatcgatg ccgaggcagc
    55861 aaagagccgg ctcgcaaaga tccgcaacaa gacaatcgtg ccggggggga aagtccagct
    55921 gaatctccgg ttcggtgcga atgtcatcgc ggacaacagg taccaccccg gggactccat
    55981 cgtcctctct ctggaacctg agaaccggtt tgcgatcctt gaccacttcc cgttcgcggt
    56041 agggaacatg gccatggtca tcggcggaag gcattccggg aaggtcgcac ggattgtcgg
    56101 gatcgagaag gttccgggaa gtgttcccaa cagggtcatc ctggaagacc cggccgacgg
    56161 gtcgcgtttc gagaccatcg atgaatacat ctacatggtt ggtcgcgagg agccagccct
    56221 caaagagtgg gggattgaag aatgaacccg atgcgcgagg tctttgtcga gaaggttgta
    56281 gtgcacatgg gagtcggcga ggccggagac aagctcacgc gggcggttga tctcctgaag
    56341 accatcacag ggaacacgcc ggtccggagc aatgccaaga ggacgaacgt atcgtttggc
    56401 atccggaagg gggctcccat cagctgccgt gtgaccctgc gtggcaggaa agcggcagaa
    56461 ttcctcagta aggccctgga tatcgtagac cggagaatag cgaggaacca gtttgacagg
    56521 tggggcaatt tctcgttcgg gatcgaagag catactgatt tcccgggcat gagctatgac
    56581 ccccagatcg ggatatacgg gatggacatt aacgtcgtcc tggcccgcag gggtatcagg
    56641 gtagcccgcc ggtcgatcga gcagcgtcgc ctccccatca agcagcgggt cacacaggac
    56701 gatgcagccc ggtacctgaa ggaggcacac agggtggagg tgtactgatg ggtggagaga
    56761 agacgaaggt attcggtcgc ggagcacacg agtgcaaaat ctgcggccgg aagcaggccc
    56821 ttgtacggcg gtacaacatc atgttctgcc gccagtgttt ccgtgaatgg gcgcacaaaa
    56881 tgggcttcaa gaagatgaac tagggggagg cagttccaat ggcaagactc aatacaatcg
    56941 ctgatggcat gtgcgccctc aaaaacgcgg ccgacggggg caaatcctcg gtcatcgtgg
    57001 agcccgccag caagctgctc ggtgcgatgt tccgcatcat gcaggagaca gggtacatca
    57061 acgggttcga gtatatcgag gacgggcgcg gaggacagtt ccgggtccat cttaacggca
    57121 ggatcaaccg gtgtggcgca atcacgccgc gttactccgt ccgcctcgac gagctggaat
    57181 actgggagac gcagtatctc ccgggcaaga acttcggaat cctcatcctc tccacgtcaa
    57241 agggggtcat cacgcacgaa caggcccgcc gggaacacgt agggggagaa ctcctggggt
    57301 acgtctacta gggaggggtg acagatggca acagaacgca ccgtgaccat tcccaaaggc
    57361 gcaaagatcg aggtcgacgg gccgacggtc cgcgtcagcg gccccaaggg ccagctcgag
    57421 aggacattcc gtttccccca gatcacgctc acgctccggg atgacacgct ggtcatctcc
    57481 accaccgctg acaggaaaag gatagtcgcc atggttggaa ccatccaggc gcacgtccag
    57541 aacatggtca ggggtgtgac agaagggttt gaataccgga tgaaggtcgt ctacagccat
    57601 ttcccgatac agctcaagct gtcgggggac aggctcgaga tcaacaactt cctcggtgag
    57661 aagaaacccc ggtatgccca gatcgtcccc ggcgtgaccg caaaggtggg gaacgacgaa
    57721 attatcctca cgggcatcga ccgtgagaaa ctgggtataa cctctgcgaa tatcgagcac
    57781 gcgacgaaaa taaagtacag ggacccccgc accttccagg acgggatata ccgggtccag
    57841 agggggtgaa tgaacaatgg cagaagatac aattcgggca atcagggtcc gtgcagcgaa
    57901 gtccgcccgg ttcaagcgcg atggttttgg caagaagaag cagctctcgg agagctggcg
    57961 aaagccgagg ggactccaca acaagcagcg gatccagaag aaggccaagg gccctcttcc
    58021 gacaccggga tatggaagtc cccttgcagc aaggggcctg cacccgagcg ggtaccgtga
    58081 cgtgagggtc cacactccgg ccgagctcga cgggcttgac ccggaaaggg atgccattcg
    58141 catcgctgcc ggcgtcggcg cgaagaagag agcagtcatt caggagaagg ctatcaaggc
    58201 aggtttgaag attctcaacc cgcgtgaaga aaaaccggtc gaagaaccgg cacctgcagt
    58261 gagcgaagaa caggaggagg agagcgatga ctgacctttc ctcccagcgg cggattgcag
    58321 cggagctgct ctcgtgcggc atgaacaggg tatggtttga ccctgaccgg cttacggata
    58381 tccagaacgc catatcgcgc gaggacatca ggaagctcat cggggatggg gcaatcattg
    58441 cacgccagat cagagggaac agcaggggaa gggcgcgcgc cctgatggcg aagagagcat
    58501 acgggcactg cagagggccg ggtcggcgca agggagccgc aggggcaaga aatcccgcga
    58561 aacgccagtg gattcggaag atccgggcac tccggaagac ccttgcagag ttgcgcgaga
    58621 aaggagagat tgagccgcgt ctctaccgtt tgctctaccg acaggcagcc ggagggcagt
    58681 tcaggagcgt gggtcatctc agggcccacc tcggtatcat catggggagg gcacggtaaa
    58741 atggcgaccg gaccacggta cttcatcccc ttccggagga gaaaggaagg caagacagac
    58801 tactatgccc gtgccagact cgttgtctcc gggaagcccc ggatggtggt gcgccgcacg
    58861 aaccgccata tcatcatcca gcttgtccag gcagagaagg agggggacct cacacgtgtg
    58921 accgcacact ccagtgaact ttcaaagtac gggttcaggg gatccctttc aagtacgccc
    58981 gcagcattcc tcacaggggt tctctttgcg gtgaaagccc agaacagtgg gtatgactct
    59041 gcgatcctcg atattggtct ccacagggca acgaaagggg cacgggtctt tgccgcactg
    59101 aagggagcgg taaccgcagg gcttgatgtc ccccacgggg aggagatact ccccgatgat
    59161 gacagggtga aaggagttca cattgcagca tatgcacccg accgtgccgg cgacctggta
    59221 cagaacgttg aacagactat ggacgccatc atgaaggagc tggagtaata tggcctatga
    59281 gaaagtggaa tgggtcccgc tgaccggcct tgggaaaaag gtggccgcgg gagagttctc
    59341 cagcatcgac caggtcctgg agagcggccg gcccatcaag gaacccgaga tcgtggatct
    59401 cttccttccc gacctcgaag acgaggttct ggacatcacc atggtacagc gcatgaccga
    59461 ctccggcagg cgtgtcaagt tccgcgccgt ggtggtcgtc gggaacagga acgggtacat
    59521 agggtttggc cagggaaagg attcccaggt gggagatgcg atcaagaaag cgatcgttga
    59581 tgcaaagatc aacctcatca aggtccgtcg tggttgtggc agctgggaat gcggctgcaa
    59641 caccgcgcac tcgattccca tggtcgtcga gggtgctgca ggcagcgtcc gcgtaaccct
    59701 caagcctgcc ccgcagggga tagggctcgt taccggtgaa atcagcaaga aagttctgga
    59761 acttgccggt atccgggacg tctggacctt tgcgagggga cagacgagga cgacgatcaa
    59821 ctttgcaaag gccacgttca atgctctcag ggcaacgaac atgatccgga cagggggaga
    59881 gggatgatgt acgccatcgt gcaggtgaga ggggttgtca atacccggcg ggacatcagg
    59941 gacaccctta aaatgctccg cctccatcac atcaaccact gtgtcctcgt gcctgatacg
    60001 cccgaatacc tggggatgat ccggaaggtc aaggacttcg tggcatgggg ggaggtggac
    60061 gcggaaacga tagagacgat cctgcggacc cgcggacgga tcgagggtaa ccgcccgctc
    60121 acggacgaat atgtccggga gaattcgtcc tacaatggaa tcgcggaact tgcagcggct
    60181 ctggctgcag gggaagtgcg ccttgccgac attcctggcg tcaaaccggt gctccggctc
    60241 cacccgcccc ggaagggata caggacgatc aagaggacat ttccgcaggg aggagccctc
    60301 gggtactacg ggaaggagat aaacgagctc ctctacaaga tgaggtgaga cagatgccag
    60361 tcaacaagag gtcgaaatac cggggatccc ggacgtgcgg gggaggcacg cacaagaaca
    60421 ggaggggtgc ggggaaccgc ggcggcaggg gccgtgcagg tcaccgtgac caccgcttct
    60481 cccactactg ggtctatggc gaagttcata acggaaagca cggcttcgtg aacccgacat
    60541 ctgacaggat gcggacgatt tccgttggaa gactccagga gatgcttgac gagctgctgg
    60601 ctgcgggtct cgcttcacgc gacggcgatg ccattgtcat atccgcagaa cagatcggca
    60661 tcgataagat acttgggagc ggaaaagtca cagagaagat gcgcattacg gcacgtgcgt
    60721 tttccggaca ggcaaaagaa aagatagaag cgataggtgg ccaggccctg gttatctgat
    60781 ccccctttgg tgaaagaatg ggagaactac tggaccgaat ggaaccgctg cttgcagcga
    60841 tgcccacggt aaaaggcccc gagggacacg ttcacttcaa gaacaagctt gcctggacag
    60901 cggggatcct catcctctac tttgtcctca ccaacatacc ccttttcggg cttaatccga
    60961 actcgcagga tatcttcttc tactggcggg cactccttgc aggggcaagc gggtcgctcg
    61021 tgcagctggg tatcggcccc atcgtgacag cctcgatcgt tctgcaactc ctcaaggggg
    61081 cagacctgat ccatatcgac acgagcgaac ttcacgggca gatccagtat atgggcctgc
    61141 agaaactcct catcttcgtg atgatcatca tcgaggcggc cccgaacctc gtcggaggtt
    61201 ttctcctgcc ggaccctgtc attgcggaca tgttcttcgg cggaaacctg ttcctggtct
    61261 cgcttatcat cttcatccag atatgcatcg gcggtgtcct gatcgtcttc atggacgagg
    61321 tggtcacgaa gtggggaata ggatcgggcg tcggcctctt catcatagcc ggcatttcgc
    61381 aggcaatcat caacggcttc atcaactggg caccggtcag tgaccagtat cccgtcgggt
    61441 tctttccccg catggtcgca gtcattctgg acagcgcaaa cttcctgcag tatatgggga
    61501 cagacctgat cgcgttcatc accaccatag gaatatttct ggttatcgta tacgtggaat
    61561 cgacgcgtat cgagatacct cttgcccatg cccaggtgag aggcgcacgt gcacggttcc
    61621 cggtcaagct catctatgca agtgtccttc ccatgatcct cgtccgggtg ctccaggcaa
    61681 atatccagat gatcggcctc ttcctgaaca acgtggggat aacgattctc ggaacattcc
    61741 agggggcaac ccctgtcagc ggactgatgt atttccttgc ccccatcaac gggcccgatg
    61801 actggatgtg gtggatctat gacctcggtc atgccccgtg ggaagtcctc ctcaggatgg
    61861 gtatcgatat cctgatcgtg gtggtcggcg gcgcgatatt tgcccttttc tggatcaaga
    61921 cggcaggtat ggactcaagg gacgtcgcac gccagatcca gatgtcgggg atgtcgattc
    61981 ccgggtaccg gcggaacccg caggttctcg aaaaatacct cgacaggtac atcccccggg
    62041 tgactgtgat aggcggtgtc ttcatcggcg tcctctcggt gtttgccaac ctcttcggcg
    62101 taatcgggtc agtgagcggg acgggcctcc tgctcactgt ttccatcacc tacaggttat
    62161 acgaggagat cgcaagccag cagatcatgg agatgtaccc cttcatgagg acatttttcg
    62221 gaaaggagta agtatgacgg gaaggagagt gatagtgaca ggtgtccccg gcgtcgggaa
    62281 gacaacggtt gtcaccgggg cgttgaaact cctcgaggag gaaggaatac cctacaaatc
    62341 cctcaatttt gggacgtaca tgtttgagac tgccgtggca caggggcttg tccgggaccg
    62401 ggatgagatg cgaaggcttc ccggagatgc ccaaaagagg ctccagcagt tagcagcgcg
    62461 ggccatgtcc aaggaagacg gaaacctcct catcgacacg catgcatctg tcaagacccc
    62521 ccgggggttc cttgccggcc ttcccgagtg ggtgctgcgg gaactcatgc ctgacaccat
    62581 catcctcgtc gagacagacc ctgaccagat cctcatgagg aggctttctg acgagacgcg
    62641 ggcgagagac cgcgagggtt cgggagcaat cgccgatcac cagcagttca acagggcgat
    62701 tgcagcttcc tattcgatgc ttacgggctg taccatcaag tacatcacga acgcggacca
    62761 cctccttgac cttgcggtgc gcgagatggc agacgtgctc cggtgaggct tatgaagagc
    62821 aggttcgggg gcatcctcgc cctcatggtc gcgatggcga tgatattttc ctacagcatc
    62881 gcacccctgc gcgagggtgt cggccggggg cttgatagcg tgcttgggcc gctcgcggag
    62941 atgatgccct ttttcatcct catcgttatc ctctcggcta tcacggctct ctattcctcc
    63001 atcatccaga agtacacgat cgattacgag aggatgaccg aggtccagga acggatgaag
    63061 gtcttccaga aagagtaccg cgaggcccag ctttccgggg acgaaaagag aatcaagaaa
    63121 cttgacgcaa agagggatcg cgtgatgaaa gagcagctcg agctctccca gcagcagttc
    63181 atacccatgg cttacatcct catcataact gtccccatat tcttctggct ccttttccga
    63241 ctcggtgtta ccccccatgc acccatcgtc atgccgttct tcgggcagca tacgctctcc
    63301 gaggcggtcc tcggaccggt cccggcctgg atcctctggt acatgatctg ttcccttacg
    63361 atcagccagg ttatccggaa atccctcaat atcgggggta tctgatgcgg atcacggtga
    63421 gcgggcttcc cgggagtgga acaacctccc ttgcccgcca ccttgcagaa atccgtggat
    63481 acagattgat atcagccggg gaagtgttca ggcagatggc gcgggagagg ggtctcgatc
    63541 tccgggaatt tggcaggatt gcagagaccg aaccgtcaat tgacagggag atcgacctca
    63601 ggcagcgcga gattgcagaa agggaggacg atatcattgc cgaggggaga ctctcggggt
    63661 ggttcgttgg aaacgcggac ctgagaatat ggctccaggc gcccctttcc tgcagggtgg
    63721 aacgcatttt ttcccgggat acgatccagg acaaggagac agcccggctc ctgacccagg
    63781 agagggaggc atgcgaggcc cgccggtatc aggattacta ttccatcgat atccgcgatc
    63841 tttcgcccta ccaccttgtc ctgaattccg agacgtttgc ggtcgaagaa ctctctgcaa
    63901 tcgttgaaac ggcaatacgg gttatcgagg agaaaaagag aggggaggcc aggtgaagac
    63961 caatgcggtt acgaatcctc gtcgacaatt ccacccacat cgaccgctat tttcttgcag
    64021 aaccagcttt ttctgctctc attgagacca ggagcggcaa ggtcctcttc gacctcggtt
    64081 attcctgtgc atttctcgaa aatgcccgca ggatgggaga agagatcctc gatgtccgtt
    64141 acgttgtcct ttctcacggg cacctcgacc atacctgggg actcattccc tatattatgg
    64201 cactaaccga ggcccggatt ggaaaaaaaa cggtttcccg ccccaggctg gttgcccatc
    64261 ctgaagtctt cctgacaaaa aagaccgggg agctgcccga aacgggaatg ttgctctcgg
    64321 aggagaagtg ccgggaacac ttcgatctgg aactctcgaa agagcccgta tggctctttt
    64381 cggacctcgt cttcctcggg gagataccac ggcggttcgg gttcgaggag atggtgcagt
    64441 cagggaagag gatgaaaaag agccccgggg ggctcgttcc cgatacgctc cctgacgata
    64501 ccgcactcgc atacgtggga gaggaggggc ttgtcatcat cacgggatgc tcgcactccg
    64561 ggatctgcaa catcgtggcg catgcccgcg aagtctgcgg gaaagacaag gtttttgaca
    64621 tcatcggtgg ttttcacctc gtgggggcac ccgcaacgag gatcgagaag acagtttcga
    64681 cccttgcggg gatgggggtc acgcgcatgc atccctgcca ctgcacgggt tttgctgccc
    64741 gctgcagttt ttccagtgca ttccaggttg aggaaattgg ttccgggtgg gaatgtgagt
    64801 accggtaaac gacaagggga tattcataac ccggcagcag gctccagggg agaagccggc
    64861 gggcatgcat gtccgggtga aacagggcag ggaacaatcc acgaattaag aggttgtttg
    64921 agcaatggct tctggtgata aatttgtggt catggtcgta aaagactggg atacaaacgc
    64981 cctggcaatg ctctaccgtg cgggcggctg gtggaaggaa gaatgggata tctccgagat
    65041 tccccgcctg gtgcgatcga gtttcgcttt tgttattgcc atccaccgcg agagcgggaa
    65101 gacgatcggg atggggagag cactatcgga tggagtgtcg gatgcgtaca tccaggacct
    65161 tgtcgtgctg ccggaattcc gggggagcgg tgcagggaga atgatcctcg agaagctcgt
    65221 cggggtgtgc ctctcccggg ggattacatg gatagcgctc gtggctgaac cagggaccgc
    65281 ggacttttat gcaggcagcg gttttgtacc gatggaaggg cacgtcccga tgcgcttccg
    65341 ggggaaggag aacgaatgct gacaatctcc cggttccggc ccgtcacgat ggatgatcgg
    65401 gatgtgtttt cccgccatta cgcacagtat ccgcccgagc acagtgataa cctcttctcg
    65461 aacattgcgt gctggaacca ttttgcccac tacacgtacg cggggcataa gggatgcctc
    65521 atcatcagca gcaccgtcca gggggtaacg acattcagac cgccgatagg accaagggac
    65581 agggaagttc tccttgacgt gatcgatctt gcggtccgcg aagggggaga aaggcccctt
    65641 gtcctcgtgg atgaaccgac aactgcctgg atacggacac tctttcctga cctttccctc
    65701 cagcccgaca gggattactg ggaatacgtc tacctgaccc gggatcttgc ccgcctctcc
    65761 ggcgggaagt acctctcgat ccgcaggcag ctgaacaggt tcgtcgacag gtgtcaccac
    65821 acagtggaag agataaatcc cggtaacctc gcggatgtca ggacgttttt acacgagtgg
    65881 tgcgagtgga agcagtgcaa tgagcatcct tttctctctt atgaaaagga tgccgtcatt
    65941 tttgccatcg aaaaattctg cgaactcggt cttgaaggcc tggcaatcag ggtaggggaa
    66001 aaaattgggg ccattgccat tttcgaggag ctcaaccggg agaccgcggt cgtccacttc
    66061 gagaagggcc ttccggactg cgagggcatc tacaaagcca tcaatgccga gacggctcgt
    66121 tttctcgagc acaggtacac ttacatcaac cgcgagagtg atatgggtgt cccgggtctc
    66181 cgcgaggcaa agatgcgcta tcacccccac cacatggtca aggtattctc tgtcgcaaga
    66241 gatgatctcg cgcggctcgt gtgagatttt ccctctatcc ctcgaaaaag tgactgcgcg
    66301 ggatataatc aaggtaacag ggaaaatctc ttcaataaaa ataaattgaa aaatataggt
    66361 cgaaaaatat gcctattttg cggtccgttt tgttgcggga gatcatcggt gcgcgttcca
    66421 aatcagtgcc aatctgtgcc gttttcaaat agaggcattt attgacatat tttctcaaaa
    66481 ctggcaaaaa tatgccttcg atatcaaaaa aggagcccgc aaagtggggg gatccgaggg
    66541 aaagatttaa attacgagcg ttagacctct tagtaagtag ttccattgag ggaactatgg
    66601 tgggagaaag aaacatgctt gaaatgaggc gtgaaatggc cgtccggaac atgaaggatg
    66661 acgatgtgat ctggaagttc aagaaagaca aggcgtgggg tttgtgtacc atggtggact
    66721 tgaaacagtg caacccggag accatcaggg acccggagaa gatccacgag ttcatcatca
    66781 agctctgtga tctcattgag atgaagaggt ttggtgaccc caccatagtc cactttggcc
    66841 ccaatgccaa ggttgcaggc tactccatga cccagctgat agagacgagc ctcgtctccg
    66901 ggcactttgc caacgagtcg aactcagcat acctggatat cttcagctgc aaggagtatg
    66961 cccccgagaa gactgccagg ttctgcaagg agttcttcgg tgcaaaatcg atggacttca
    67021 acgttgtttt ccggtactaa aaagatatat ccatccagtc acccgttccc cttttgggga
    67081 agtgggatac cccatttttt gagatggctt tttcgtttgc agattcatat cagactgctt
    67141 attccattta cgtgtccttt tgggggaatg gtcgcgacac agtgaccccc tccaggaaga
    67201 ccagacgcct tttctggtga atataaaatt atcagatcag cccgatgatc ccatcggcaa
    67261 taatcttgac tgcgattgct gccacgagca tccccaggac gcgtgccatg atctcggtca
    67321 cgcaatcgcc aagtaacttc tggatctctg ccgagaagcg gaggatgatc cacgtggccc
    67381 caagggagag ggcgattgcc acggcaggta tcagtatccc catgtcgttg acgaggagaa
    67441 ttacagtcgt tattgcaccc gggccgcaaa ggagcggagt cccgatgatg acccctgcag
    67501 cagaaggcga atgatctttc ggccttccga tatcgatgcc aagtgccatc tgcatcccga
    67561 gaataaagag gaggaatccg cctgcgacct ggaaactggg caggctgatg ccaaggatat
    67621 cgaagatgaa gaagttgaaa aagaggaaaa tatagaggag aaaacctgca actgcgaccg
    67681 caatcacggc ctgcttgctt atctcggcag atgactgtcc gcgggtcatg gacgcaaata
    67741 tcgggacgct caaaatgggg tcgagaatca cgaagagtgc cgagaacgcg tacaggagag
    67801 aacccaggaa atctgccatg tctggtgaga tggtttctca cggtgagtat taaatccgcg
    67861 gaagagggag ataggggacc cgggacagcc gggcggttca cttgtgaggg attgtacgac
    67921 aaaaagcgaa aggttaaaat tgactggaat aagcgatact gccagaacag gggagtcgaa
    67981 tcaccatcgc ctggagagag gatgctcatc tggattgtcc ctgattgata ggggggttga
    68041 tgccagattc tgggggtatc cggcaaacaa aaagaccagg cgactcatcc agagagcatg
    68101 tactgttttt cctttcaaca ttaaatacta ttcagactgg cgatgaacag aggagaggaa
    68161 ggccgggagc gtcctcattc ttttacggag tcaggaaaaa tgccgcacaa atgcctggaa
    68221 aatagaacgg atcttatccc tgcagaataa ttctaccacc cccatcaccg cctgtccacg
    68281 agccgcctgg gccgcccctt tacgcggtac agttcaaggc cgccgggtgg taaaaaggag
    68341 aagacaatct ccagttcatc cccgatcagg ggggcaaggc ctggtttata gcggaaaaag
    68401 gaggaaagaa acctttcctc aacatcttct cttcgcactg cgccgggatc acgggcctcc
    68461 atacttaccc ggataacgat acccccgtct tttcctgcgt agacgaatgc ttcgtattcc
    68521 ccggtcaggt aatccatgtt ttccggctgg aagacgcccc gctcgatgtc aaccctgtta
    68581 accgggatcc cgtgaatcca gacagtctct gcttcccttt gcggggtgaa gatcttcatg
    68641 tgcgtcctcc cacaggagca cgggccgcgc gtgaggacaa ctgtcgtatc ctcggtatca
    68701 taattgatga ggagcgttcc gcaccggcca ccgggaggaa ggagtgtggt gagtattgcg
    68761 cgtccgcatt ctccgtcggg cacgaatgtc ctgagagcag ggtcataaac gtcgagatgg
    68821 acgagatctt cagggacgtg gagtccctgt tgctcggcac actccccgca catcgtcccc
    68881 tcggtgctcc cgtaggtgtt gtagacattt ctgtcccaga ccctggcaag gtgcgcacgc
    68941 gcctcctccg agaaactctc ccccccgaca acaagcctct caagagacgt ctctttcggg
    69001 tcaatgccct cgcttttcag ccggtcggca agatgaagga gtttgaagac gcttcccacg
    69061 atgccggtcg gcctgtagct attcaggatc cgtgtcggga acgagcattt ccccgtcgga
    69121 atgatggtca ttccaatatc cctcgcggca agcgtcatcg tatttgcacc cacgttcatc
    69181 ccgtaggacg cgcatatcac gaccctgtct ccttttccaa agccctggga tacgaatatc
    69241 cgggcatatt ttgcagcgta tctcttccag tcttcccacg tgaggaagaa actcttgggg
    69301 gtccccgatg tgccgctggt ctcgtgcacg gtgaatatct cgtcccagga gacactcctg
    69361 aacatgaatt caggggtcag ggggggctgg ttctcacgaa tcgtttttcc cgagacgatg
    69421 gggagggtta gcagatcctc atgttcgcga atggcaccag gttcgatacc atgctcccga
    69481 aaccacttgc ggtagaaagg cgagtgttcc tgggcatatg caacggtgta ccggacccgc
    69541 tcgtcaacaa gagcatcaag atcgccgcgg gacatggtct caatggccgg gtcaaagaat
    69601 gggtctctcc ccatgaggag agaatatacc gtgcaagatg atgagactca ccgttgtgca
    69661 acccatggga acactgcatg gacaaaccgc gcaccgaaga cgcaaaggat cctgctgccc
    69721 tgagaaatac cattaacacc ttggaggaaa attctcgtaa atgtccggaa gacggatgag
    69781 gaaaaacaat gaaaaagagc aggaaatcgg accagaatgt gaagagatac cggtgccgga
    69841 tctgcgggta catctattca ccccttcgcg gtgaacccca caacggtatt cccgcaggaa
    69901 ccgcctttga ggacctcccc gagacgtacg tctgtcccat ctgtggaatg gagggcaagg
    69961 gcaagatagg gaagtggggt tttgaggagt gggtcccgac gaaatatatc tgtgtcgtct
    70021 gcgggtacgt atacgacaag gacaggggag agccccaccg gggcatcaag ccgggaacac
    70081 cgttcgagga tctccccgat gactacacct gtccgatatg caaccttgac ccgaagattt
    70141 ctctccagtt tggaaaggtg ttcaagcagg ggttcgaacc gctctatatc ccctgaaaac
    70201 tccttttggg gagtatttcc ggatcagcgg agtcgtacac agccatctgc cccctcccgg
    70261 gcttttacaa gctcgatgag cagggagaag actgcggctt caagagggtc cctgatagcc
    70321 ggtatcccgt cgatggcatg ggaccggatc atggcagcaa ggcattccgc gtaaggcctg
    70381 tcttctgcag ggagggctcg tgctgcccgg agccagcgat cggcagtctc atggagatcg
    70441 gcccgccctt tccggttccc ggccggtaga acgtgcccgt tcatgtctgc atccatcctc
    70501 gcagtgaagc atggcagtca caccatgatg aagggtgggg caggcggggt gaaagtgccg
    70561 gcacggcctg ttccggccag ctgaaaaggt aaaggtaact cttaactccg acctggcgaa
    70621 aaactcatgt aatcatgaag aatcccttcc acgtgatgct catccccacg ctggggtgcc
    70681 ccgcccggtg caggtactgc tggagttccg aaccggggtc tccccggatg agcattgcga
    70741 cagtcaggga cgttgtcgag tgggtctcat cccttggaaa ggagcgggtg actttcacgt
    70801 tccatggtgg cgagcccctc cttgcaggtg cggctttcta ccgcgatgcc ctccccctcc
    70861 ttgccgaggg ggtggcgcag gcaaaccccg agtttgccat gcagtccaac ctctggctca
    70921 tgacccctga aatcgcagag atccttgccg aataccacgt tccgatcggg acgagtatcg
    70981 acggtcctgc ccggatcaat gatgtccagc gtggcgaggg gtacttcgag aagacgatga
    71041 aggggtaccg catcgcacgg gaacacggac tccgggtaag tttcatctgc acgtttacat
    71101 cgcaatcctt ccgggaaaaa gaggagatcg tccggttctt cagggagaac gggttcacac
    71161 tcaagctcca cccggcactg ccatcgctcc gcaacgataa tcccgagccg tggacactct
    71221 caccggatga ttacggggat ctcctcgtat acctcctcga tgtctctctc gagaacctgg
    71281 ggtccttcga gatcatgaat atcaatgacc tctgcaagtg tgtcttcttc cggcatggga
    71341 ccgtctgcac gttcgtggac tgcatgggga gcacgtttgc cgtcggtccg gatggctcga
    71401 tatacccctg ctaccggttt gtcggcatgc cggaatacgt gatgggacat gtttcggact
    71461 gtcctctgcc agaagacctt gctgcgtctc ccgttggcga ggctatgcag gagttccgga
    71521 gtttcgtgga cagggcttgt gcggactgcc cgcacatccg gtactgccgt ggcgggtgtc
    71581 cctacaatgc catggtcccc ggtcacggta ctatcggagg ggtcgacccg tattgcaggg
    71641 cataccacag gatttttgac gagatctcgg ggcggctgaa ccgcgagatg gcagaggctc
    71701 cggcaatgga gatgatgtgt ttcggggctc cgcgccagaa gcaggataaa cccggtgtca
    71761 tggccctgat gcgattccag gccatgaaag agggaaggag aaagcgttaa ccggggacca
    71821 aaccggttga tggagaccct ctctgacctg atcctctcat ttctgctgct ccaacccggt
    71881 tcatgggccg acgggggggg actcacagat tttttcccgg ataagaagta tacgctgcca
    71941 tcccgtatca gccctgtcgc atgaatgaat gggtgcaatc ccatggcaac ccccccatgt
    72001 ccaccgtgca gccgggcaaa agttttgaaa atcacgaaag cagttttggc atgataacag
    72061 ccaacgcgtt tttttatcag gagacctgca ggtcacactc ccccgtgcag cgcaagtccc
    72121 ctcatgtttt tcactacccg ctcttcttcc tgcataatct ccctgtccgc atgccagacg
    72181 cccctcccat tatgtatagc ataatagagt ttagaaaata ccggcttccc gggcaggtgt
    72241 gaaatctggc ggtatttttt gttccacctg atacgatgcc ttcacatgat gacaggcccg
    72301 gaaaagaact gggaaataat gcgggagggg aagggatttt ccggatcatc agtccctatt
    72361 gaatccggtt acgttgacat cagcagcttt nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    72421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    72481 nnnnnnnnnn atgcacatgc ctgcggcatg tgcatgcaca aaaaaaagtt taaatgagtt
    72541 tgaatatcgg gtggttttcg gccttgcagt cgatgcccag ggggcgcatt gcctccaggg
    72601 tgacgatgtc catgtaggcc tgcgctgtga tcatgggttc gacgttctcg atgggtccgt
    72661 acatgatgag gtccgcaccg agagtgctcg cgacgaggtt gcatccgata tcgggagcag
    72721 accatgcagc ctggacgaca ccctcgatac cgccctggta gtggtggagg agctgtttta
    72781 agtaaatgtc cttccccttc agggactcga cgagctggga cgggttcttc tttgagcctt
    72841 tccagcgctt gagccaggtc caggcaaccg tcatgttgtg gtaagcacca ccggtcgggt
    72901 aaccgtggat tgccttgcag gcaaggatct cgcggtaagc actcccggat ccaaggccga
    72961 gcggtgtggc agcggtgtcg aggatcgggc gggtgatacc gcactcctcg gcaatctgga
    73021 gcataccctt ggcctgaccg gcgactccac cctcgacgag aactttctct ctccctgcaa
    73081 cggacgggtc tgcggggttg aatgccagca cgatcgcagc atcaacgtca ctgttcttga
    73141 gggcctccac gttctccggc aggatggacc cgttgatgga gttgtagatt gcccggtgtg
    73201 caagacccac ctctgtcacg tacttgcacg cgtgtgcaag gcacgcgggc acagaggagt
    73261 ccatgaggaa cgcagtcttg ttgtcaatgc tgtcgaacca ctggaagtag ctttcgaatg
    73321 cctgcgggta ttccgcaagg atctggatga agtgaggaat acccaccatg tcggagagtt
    73381 cctggcacct gttccagagt gcttctgcgg ctgctttgtc tatctttccg gtcttttcgt
    73441 caagcacaat ctcgtgcttg ttgtaaaaga ttgaacatgc aagtacggtc gggtactctc
    73501 caggctgacc accaatcttg gtgccattga agtcccagac tttctgttct ttctcaaacc
    73561 tgaacatctg aattcacacc tccttcacat catcatattc agcttcggga gcaggaccag
    73621 cagcatgacg aatactgtca gtccggcgac cagtccatag aggatgccaa tatcccggcc
    73681 gatcttcctg cccacgcgct gggcaacctc tgcatcgaca aactcgatct tcttctcgat
    73741 cttgtcaagc cgtctctcaa tctccaggaa ctgggggttg acgcctgcag cggcaacttc
    73801 gaccccgcct gccgcagact ccttgacctc gacgaccatg gggtcggctg cgaacgcacc
    73861 cgggtcacgt cccttgagtt cggcgatctt ggccttgatg gcgccgagat cctcggcctc
    73921 catgatgttg accagttcga cctgctcctg gaaacgcttg atggcgtcct ccttgaggtt
    73981 ctcgatgaag gggatagcac cctctgcacc gacgaccctg ccgtccttga caccgttctt
    74041 gtggagggcg gccattgtct ggccggcgag gtgccccttg acctcggttc cacagaggag
    74101 gaggaaccgg atgttggggt tggagatgat gttggcgatg accttctcga gaccgaggtt
    74161 ttcggtcttg caggacccgg cgatagcggc tccgccatcg cagatggctt tctcatcgag
    74221 gtgtgacccg caggtcatga ccgcgacggg actctgtggg tccccggcgt ggaagtctcc
    74281 ctggacgatc ggccacccgc ttgctggtga tttcttctct gccatctcac tcacctcata
    74341 ccaatggcag gcaccacgat caggataagt gcggtcagca gacctgcggc aaacccgatg
    74401 ataccggaac cgaggagtgc agagtcgtac ttatttgacc tggctatcaa ctgggccttg
    74461 tagcggatgt tctccatcat gttctcgatg gcaaccatcc tgattggccc tgtcattttc
    74521 tgtccttctt ctgccatttt tcctcacccc atcagcatga acccgaggat ggcgaacgac
    74581 acgatgagac cgatcatgat accctcgatc ttaccggaat agacaccggc agcgaacttg
    74641 tcgcggtacc cgatgtctgt caccatcttc tcgattactt tcatccgtgc gtgaatgagg
    74701 gccagttctc cggacatcgg ctggacaacg ccacccgctt cctctgcacc gccacctgcg
    74761 gcctccttga cctcgacgac catggggtcg gcggcgaacg cacccgggtc acgtcccttg
    74821 agttcggcga tcttggcctt gatggcgccg agatcctcgg cctccatgat gttgaccagt
    74881 tcgacctgct cctggaaacg cttgatggcg tcctccttga ggttctcgat gaaggggata
    74941 gcaccctctg caccgacgac cctgccgtcc ttgacaccgt tcttgtggag ggcggccatt
    75001 gtctggccgg cgaggtgccc cttgacctcg gttccacaga ggaggaggaa ccggatgttg
    75061 gggttggaga tgatgttggc gatgaccttc tcgagaccga ggttttcggt cttgcaggac
    75121 ccggcgatag cggctccgcc atcgcagatg gctttctcat cgaggtgtga cccgcaggtc
    75181 atgaccgcga cgggactctg tgggtccccg gcgtggaagt ctccctggac gatcggccac
    75241 ccgcttgctg gtgatttctt ctctgccatc tcactcacct cataacaggt ggaacacgta
    75301 gacccccgcg atcaggaggc ccactgccag tccataccag taggcagtgg ctgcaccggc
    75361 cgtgggcagg gcattctccc tgttcgggaa ggatgcaagg aagttgccct ctccggcgag
    75421 catgttcacc atatcgtcag cgatcgcttc gaggtccccg accttctcga tgatgggtgc
    75481 aagcgactca cctgcagtgg tcacaacccc gatcatcggg tcgcagacaa gtccgtattc
    75541 gggaagaacc tggacgtaca tgtcagtgtc cctccagttc cggaatcggc tttgcatcga
    75601 gccaggcagc cgcatcgcgc ttggaaaggt cgatatactt cgtgtacgtg tagtaccagc
    75661 ctatgagggc cacgaccagg gacacgagac ctgctgcaag ggatacgagc gccatggaca
    75721 tgaccgcagc ggtgatcatc gagaggaaac cacactcctg tgcgagcgtg agcatcctgt
    75781 cctgcgtcca gttcggacca aggcatgcgt tgaacgggtg ctggactgca ataccgccga
    75841 gcatgaatgc cacggcaatg agagatccac cgatgaagga tgcctggtaa ctgggcaggg
    75901 agagccccat gatcgttatg gaacctgcgg tcaggggtgt aaactcgaac gaccctgtca
    75961 tcatggctgc aaagcccatg aggacgagtg ccccgacgat ggccatctcg gtgagtgact
    76021 ggatcatcac aggtatcctc atgttcagga cgttgtttgc gaggaacccg aggatcgcac
    76081 cgatgaccgc ggcgaggacg actgcaacga ttggtgatgc aacaccgaac tttgttgcga
    76141 acagcattgc aatgacacca gatccgaatg ccatcatccc ggcggaggga acacccgtac
    76201 cgataccgta gctgcacagg tgcttgatgg tgtgacttcc ccaggttatg gccgcgacgg
    76261 ctgcaagtcc cccgaagaac gagaagagct gcgtctgcgc gaggacgttt gcataggtca
    76321 ggtagacgaa gatgaccgat gcaacgaggc ctgctgccat gatggtgttg tggggaattc
    76381 ctccctcgac tacttcaacc ttaactgtca ttttctgcac ctcacatggc cacgatcagg
    76441 atggcgacca tcccgcagag ggctgatgcc accgcggagg cgacgagtgc ccgcgggaaa
    76501 cgcttgaact tcgggtcgtg gggcccctcg attgtcccgg tgatgttgta ggcagtgagc
    76561 acggcgttga cgaggaacat cccgattgca aaaatccctg caaggctgac tgcgatcggc
    76621 agaacctgtg cggggagtgc cttcatcatg ccggggagtg cctccttgta gacatcgagc
    76681 agcatgatgt agatgagagt cccgccacca ccgccaagga gaccgccgat gacaccacca
    76741 acgtaagaga caaacggcag gccatgccct tcagtcccct gcgacttgaa ctcggtctgc
    76801 gtgtcacccg tgatagggtc ctttgcgacc ttccccgagg cacagggaat tcccatgcca
    76861 aagacataga tgaaggtcac gaacatgcag gtgatggcca tcatcaggcc gccaccgact
    76921 gcgccggtga tgaccgcgac aacgaggccc tgttctgcgg cccatgcacc cccaaagagg
    76981 cccgcaagac ccgcaccggc agcgagcatc gccacaccgg ttgcaatacc gggtgcctgc
    77041 cccattgcgg caggcgctcc gccgacaggg acgaagtgaa caccgaatgc gatcaggagt
    77101 cctccgacga taaccccgat gagagcgtag aacatcattc cggggccgac aaggaagtac
    77161 gtcgcaccga cgatgacgag caggaggatg atgcctgcaa ttgtcgaggg tatgtccatt
    77221 gcggctccgg ccgctggttt tgcgcctatg gcagacatgg tctcacgatc cctcctttgc
    77281 aggttcaccg tacggcccgt agttcttccg tgcccagacc tcgatgtagc ggtcgatcac
    77341 ggtgaacacg aggatgatga tgataccgac gatgattgca ccccagccag ctccgacctt
    77401 ctcgaagagg acggtacgcc agagctcgag gaacacgatc agtccgaagc agagcccgga
    77461 agccggtcca cccagctttg ccgagaacca gccgttatca agggagttcc tctccccggc
    77521 ctctgcatag cggacgatgt ttcctgacgc tgcgatgggg acgccagccc cgaacttctg
    77581 ggtctggtac tgacgctcct tcccgtagaa cgggtttccg gtcgcagaac cggctgcgcc
    77641 gagggcgata ccccacacga gcccgagcag gggcagtggg aaggggtgac cgagtgcggc
    77701 gttgatcaga tgacagatgg tcacggtcgt gaatatggcc acgaatgcgt gggccatggt
    77761 gaccgtggtc atcgacttca gcacgtcgat gaagacgggc tgaccaaact tcgacaggct
    77821 cgcaatcctg cccaggtatg cggttgttgc atacacgccc tgcacgaata cggcaagggc
    77881 actgccgagc acgatagcga gtatcgggtt gacctgcatt gccatgaatg cccaggcaag
    77941 accggcaccg agtgcaaccc acaggccgta cgccggcggt tcaccggcga tggccttgtt
    78001 gaagatgcgg tggatatacc ccatctgcgg agccagctga acctgggagt tcgggtcacc
    78061 ctgcgacccg atatcagatt cagtgttctc cgctgcaccg gctacagtgg caagagctcc
    78121 tgccaatgca gttattccaa tgccaaacgc aatactttcc atttagcctc ctccctgcgt
    78181 gcgtagaaga gtgcacgaga gtgttcaatc agcattgcca ctcacatcga gtacaaaccc
    78241 tttgtggttc atctaacagt cgatgatgga agagttaaag gtttcgaaat atttgcttat
    78301 atacgcgatt atcacggcgg aatcggcaaa aaaaaggttt taccggcact ttgtgaacta
    78361 taattttagt taaatcaaat taaattgttc tcttatcagg ggaatattcc catgagtccc
    78421 tgaaggttcc gttccaggat cagaatttta aaaaaaagaa gggggtattc tttgggcttt
    78481 accgtgcggg gatgatgagg gagcgctctc cggcgggcat gtactcgcgg attgcaccac
    78541 gggcgaactc gcgcctgggc tcggcgaagt cgaacttgag cgaggggtcg gcgaacgtga
    78601 tcttgatcag cgggttgagt gtccaggcat cgccgcgggt gtagtgtgct gcaccgcaga
    78661 ttgccgcgta ctctccctgg tgaccgacgt tcatcgcgta gttcgggtag ttgggcccgc
    78721 ggagctctcc gacacaaccc tcgtctgcac ggatggactc ggtgtttgcg gaaccgcact
    78781 ggtcctgcag gtcgtatccg tagaagccga gccgtgacca gccctccttg tgcaggagca
    78841 tggacaggta ccagccgttc agtccggcat tggagttccc tgtggcaatt gcggtcgtga
    78901 gaccggatgc agcagcaagg accgacgcac gctgggaacc gccgaagtgg tcctcgagtg
    78961 cagtcgggaa gtgctcgtac tgctccatgc cgtagagggt gacctccgtt gcgatgtcgt
    79021 tgacgatgtc ctgggtcggc ttgaccttgt ccttctcgtt cgggttctgc cagtcgactt
    79081 tgtatttctg cttgatgtag tccataccgt agtaggtata gtcatcgagg atgttgtcgg
    79141 tgtaggcggc agttgcgtac tgcgtgaacc cgacaccgcc ggacatgtag gacccgagcc
    79201 agatctggtc aaagagcatc gtccctgcac ccacgacctc gagggaggcg cgtgcggggt
    79261 cgttcgggta cttcctgtcc gtctggacca tgtcggcaaa gtgtccgaac ttgatgccac
    79321 cgggctcgtt cgggccacgg gcacggcgtg caggcaggat ctcacccatc tggatgacac
    79381 cggcgtgctt tgctgcgaat gcaaggtcag cggtcgccgc ctcaccggcg cacatgcggt
    79441 aggcaccgat gaaggacatg ccgagctgca tcgcagacca gcgggatgtg gtcccaccat
    79501 cacaggtcct cgagacgatg gtcgggatgt gaatggcctg ccacatggac ttgccgacgg
    79561 cagccttcag ctgggcagcc tgcttggccg ggaagagctt ctcgatgttg atcacgaact
    79621 ggggctccag gtcgtcaacc atctcgtcgt ccccggtgaa gaccttgagg taacagtcgt
    79681 cgacgaggcc ggggtgggtc tcgaccatgt gctcctggac cacggcggca ccgggcatcg
    79741 cgtggttgac cacgtggagg tactcgttga tggtctcggg ggtcacttcc ttgcccagcc
    79801 tcttctgcag ggtctggtgg gcaagatcca tgttgacgat gatcgtcctg cggatatcgt
    79861 cccacatctg ctgcatggca gcgttgttga cgaagtgcag gtcgtcaccc tcgacgaaca
    79921 cgccagtccc ggagacctcg taggtcatca gctggcgctg cccgagcggg ataccaccga
    79981 ggtggcaccg gacggggtca tacatggaga taccacgggc catctccgca gtctttccag
    80041 ccttgacgaa ctccatcttc ctggcagact gcttgagacc gatcctctgg tatacagttg
    80101 ttgtgctctg ggggtcctct gcgaacttgt tcttgagggc cttcaggaag agcttctggg
    80161 ttctctcaat cttctttgcc atgggtatca ctccgtcggc atgaagccgt attttgtcct
    80221 cagggcgtgt accctctgga cgtattcgat atactcctgg tcagaccgga agggtactcc
    80281 gacgagcgag tggaagatgg tgctgtgctg cttgagccac ttctcgtcca tgggcttgcc
    80341 gaccttgact tccttgtcca gcggctcacc gatctggttc ttcacgtact tgaccactcc
    80401 tgcctttttg tcgagaatgc acctctggag catgtcgaac atcatcccgt cctcggagag
    80461 acggagggag tggccgtgca cggttgcacc acggataccg gtgcgggccg ggtcgaagat
    80521 ctcggtggcc accagttcct tggccagctt ctcgaggtca cgctcgcggc actccacgat
    80581 ctggcgaccg gagagcgttc ccgggtcgac accgcggtac ctgtacgcgg cgatatagga
    80641 cctcaggtag ggctggcagg ggccattgta catggaatca gcaaactgga tgtaccggat
    80701 gcggtccccg tgcttggcac catcgagcgg tgtcaccagt ttcctgatgg ggcagtccgg
    80761 ctcctgctgc tcggtgagcg gcgggtgcga agtcgggtag gctgcaccag gggccctgtg
    80821 tcccatgatc aatacaatgt cctcatcaga gatgtcccgg accttctcca gtttcttggt
    80881 tgggtccatc accctgcgcc tgttctcggc gacggtggag gttccgggcc caaactgtgg
    80941 tttgtaagcc atttttttat cactcctagt ttttgatcaa ccgcaatact gcatgaatga
    81001 cttctgccat cttctcccgg gtcggtgtct gtccccgggt caccccgctc acgattgcca
    81061 tcacggtccc ctttgtcttc accctgtcgg gggggggcat cacgagggcg gttttgacac
    81121 cttcctttgc aaagtcctcg aagtcgaccg gtgcctggga caccacaatc gccttaatat
    81181 cacaggcctg caggatgaaa cggaccttgt ggaccacgtg ggaacggacg ttcccatggt
    81241 ggaggatggc gacgcggtgt ttctctatct gaccaatctc cttctctgtc aggccgaagt
    81301 atgccccaag gactgcgcca ccgatgtttg ccgcatcggg tggcacgcct gaaccggcat
    81361 tgaggacgag cgtgctgatg ctgtactcga caccctgctg tcggagtgca gaggtgatgt
    81421 cgcacacggg ttttgtcacg tggcgtctcc cgggggacat acccaccacg atgacatcgg
    81481 ggtagcggca ctcggagatc gtccctctct gggcgatccc gccacctttt cccataccca
    81541 tggtctctct gcagtcgacg acctgggtga cgcgtcccat cggcatgtta cttcgttccc
    81601 tggagaatga caagcccgga cttccccggt tcggtgagac cgatgatatc tctgtctgca
    81661 tccggtccgt acttggcata atccacgagt gacggtgcag tcttcatgaa ccggccttcc
    81721 tgcaggtacc acgaaaattt cgtgataccc ttctcgcagg cttcccggat ggcagggata
    81781 aagtccctgt tctcgagttc aagcacaatg ttcccgacat gcacttccag ctggacgtcc
    81841 tggtccccga ttttgatctt cttccggtat tctgttggat tgggaagacc ctttgcggga
    81901 ccatagggga cggtgggagg gaggcggggg ccattcagga tgaccctccg gacccccccg
    81961 gtgccaatga tcaggttcat tacgcgctcg actgtctcgg ggttcatgag acgttcagtc
    82021 actatcctga cctgaggata tatggcgtct gtcattctat cgactggatt tatactgcct
    82081 tcgcaatgga ctggattggt ttcttgaaga catccagctg cccgaatgtg tcctggtaga
    82141 ccttcgaggt ctgctcgggg ccgaacatct gggtacctgc atcaagcgca caggcgacgc
    82201 atacgcacgg gacagcgaca ccggcagcgt gcctcgtcac gacgtggttg ccgttgaaca
    82261 caccggggcc tccaccaccg tagatcgagt ggctgaagaa ggagaacccg acggcagttc
    82321 ccatgacacg tccgtagtcg gcactggtga gtccggtctc gtgctcgagc aggtcgttga
    82381 agtagagcag cacggatgat actgcctggg cgaaccgtcc ggcaccacag ttgaccatgg
    82441 tcgcggccat cgtcccggcg caggcatagg cattccacag catcgggtcc tttgtctcgt
    82501 agaagatgta cccgctcttg cccttcttgc ccggcttgat gaccttgtcc tcgatggccc
    82561 tctcaacaag gctctggacg acagtaccaa tcgttcctgt cttgccgttt gccttgacga
    82621 ggtcatagac gaggttgttg gcattcaggc cctggaatgc gtatgcaagg agctgggcgc
    82681 gctcaaaggg accgattgcc attcccatct cgaactctcc ggcctgctcg taggtgcagg
    82741 agagggctgc ggtctgcatg gcattccggt gtgtcatcat ggccacgtgg ttggccggga
    82801 tgttccggag tgcatagcca agaccctcgt tgttctgggg aatggagagc acagagatga
    82861 tatttccgcc cgccatgtcc attgtgaccg ggtacgaacc ccagactgcg gacttgacgt
    82921 agggggcatc ccacatgccg actttgtact gctcgacgag tgccagtgtg gtggctgctg
    82981 caacggctgt tgtggcagca tcgtaggttg ctgctgcctt caggcgtgcg ctcgggacct
    83041 cgacgaggag catcttgcct ccgccgacct tggtaatctt ggtgtcgtca cccttggaaa
    83101 cggagacata ttcggcaatc ttctcggaaa gtgcgtctac atccttgacg cagtcacact
    83161 tgattgccct gccaaggatc tggttgttct ttcctcccat tgctccggtc ttgagggcat
    83221 tgtcaatccc ggcaatgttg acggcgacag tcctcttggt gaggtcaatg atcttgagga
    83281 ttccctcatt gttcaggggg ctgatcttgt cgaggctgac cccgctcttg agcagcttcc
    83341 cattgtcgtc gtataaatca caggtgtctt tgtatttcgc cataatttat cctcttttga
    83401 agagttctgt gcttcgatac gctactttaa ctgaacgatg gcatacgcta taatgaacac
    83461 tgatgttgaa tgtaggtcac tactgcacgt cccctcacgg gacaatctac tatactgact
    83521 atctccataa aaggtttctg atttaattct ggaatttaaa aatataaaaa taaatgaata
    83581 atagcccatt ttttgggaaa agttcaaata ttacaccgtt tttatctttt cctttttaag
    83641 gtattaacac aaaaataaaa ataagtatta ttttatattc cattaattta ataatcgtct
    83701 gaaaactatg tgcgctctgt gaaaaaaaag tttagatctt gaggtataac ttgccgtaca
    83761 cgatttgacc ctttctcttg gggtgcctct cgccggtatc accgtggtac agggcaaaga
    83821 gggctttctc cccgtcgacc tcgacttcct cgtcctgcac gtacttgaag cccggcatca
    83881 tcacgtcgat ggttccatag acgaagatct caccgccgac catctggccg cccaccttgc
    83941 tcggggcatt gcccttgatg atgatcctgc cgccctccat gtgggtgccc acgtgcacgt
    84001 cggaatttcc atggacgatg atggtcccgc cgttcatgaa gtacccgatg tcactccctg
    84061 cattgccctt gacgcggatg aggccgccct gcatgccccg ccagtcaccg cggtatgcag
    84121 caccaaggta atccccggca ttaccctcga tgaggaactc gccgcccttc atgccgatgc
    84181 ctgcaaagga atcgacgttt cccttgacga cgagttttcc gccctgcatc caggcgccgg
    84241 tgtacatgtc cgggctctgc tcgacgagca cctcgcctgc cgacatcttc atgccgatgt
    84301 acttgacacg gctcacgtcg cccttcacga caatacgggt ttctgcggcg gttgcccctc
    84361 cttccccggc gatctcgaag tacttgccca gggtcgtctg ttcacgtccc tcgtaggcat
    84421 ggagtgccgc gatctcggag gccttcttcc cggcaaactt gtccggggag atgttgtcag
    84481 cctcgaggta gagtttgggc tggttcttca ttgtgattgt tacagtctcc atccatccac
    84541 ctcagtgcgt cgcatcgacc tcgatcacgt gggggttcgg gacaaagtgc gaggacacat
    84601 cgtagtttgc ctgcgtcacg ctgtagtacc gcaggaactt gtccctgatg tcccgcatga
    84661 cctgcgggtt ctcgttgacc tttgccttga cccagagcgt cctcttgttc ccgttgctca
    84721 cgatttcgcc gttgatgacg accggaacac cggtcttcat gacgtaggca gcagccgaga
    84781 atgccttctc gatgtcttcc ggcttgtgcg gtttctccgg gttgaaatca tagacgacga
    84841 tatctgcgtc catgccgggc gcaagaccgc cgtactggcg ggagagaccg agcgccttgg
    84901 ccgggcctgc acgggtcatc tgggcgatct cgtagaggga gagttcgcgg tcgatccctg
    84961 cgatgtgcgt agcctcgacc atcttcgcgc tgtgcttgaa ggactcgatc tgcttcttgc
    85021 gtgcctcggc actcatcagc cacttgatga tacgcgggta ccgtgtgaac ggccctgcgt
    85081 tcgggtggtc cgtcgtgatg aagcagcgca tggggtcctt tgccatgagt gccagctcga
    85141 gccctattgc ccactggatc tcgcagacct tgatgtccgg gctgtagatg tagggcacga
    85201 ttcctgccgc tgtctcgagt tcaacgtcaa cgtttgccca cttgaggtgg ttcaactcgg
    85261 tcaggtggtg ctcgaacggc ccgtcggcgg tcatcgtcgt ggtctcgtcc agcgtcacgc
    85321 agccggtgtc aacggtgatg ttcttctgct tgttgacgta gtccatcacc tccttggact
    85381 tggactcgaa gttcgcccag ctgtccccac cataggagtg gaactggagg tgcgtggaat
    85441 gcaggacctg ctcacgcccg aacttgttct ttgccttgaa cccctcggca agtttcaggg
    85501 tatcgagggt cactgtgtag ttgcccgggt tcccgaggct gttctggtga atgtgcaccg
    85561 agtgcggcag accaagggcc tcgtttgcct cgatcaggcc agtcactatc tcccgcgggg
    85621 tgatgtcgaa gtacgggacg gggtcatcga tggtgaggca gttgaggccc cagccccagg
    85681 cttccgtccc gccgggattc acgaccttca cggcatatcc cttcgtggcc tcgaggagcc
    85741 aggagatata ggcgcaggtg ttctcaatct ctttgttctt caggtactcg agaacgaacc
    85801 agttgttccc aaagaccggg tatgcccctt cgtcgatgat aggcgtatcc ttgatttcct
    85861 cgtggacatg ccgtgcgtag agggggggca tcgcagcttc catggccgtc gtatacccca
    85921 tgcgggcata ctcgtatccc gtcttgaaag tggtcggaat cgagaatcca ccggccatgc
    85981 ggctgctggc actcttgggc ctgtaggtga agagcttgtc ttcgggcctg tagttcctgc
    86041 cctcgttgac cttcggtccc gcgatatggg catgaatctc aaccgcacca gccatcacgg
    86101 tcttgccact tgcatcaatc gtctttgctt tggaggagac ttccgttgat ttgacgatct
    86161 tgccgtcttt gactgcaatg tcagccttgt cccccttgat cccctgggtg gggtcaaaga
    86221 caaagccgtt cttgatgatg tactctgcca tctattttcc tcccatcagc tggtcgagcc
    86281 gggcgttcac gcgggtgagg aactccacgt cggtgagaac tccctcgggc gggtcaacga
    86341 ctttccgggc ctctatcggg acgttgtcca tgcgatagca gttgccgccg acctcgaccc
    86401 ccacgaacgc tacagggacg tggagcttgg atatctccga cgtcggggtg atatgggggt
    86461 caacgcagac agaggggagc tcggctatct tcttcaccga gctgatcggg aaatgggctc
    86521 ccggatcact cccgaggacg aagacggcgt cgacctcgcc cctgcggagg agatcgttgg
    86581 aactggtctc tcccgggttg taccgggcga agccgcggga cagatcaacg gagaacgggt
    86641 acccgaactg ccatccaagg acctgtcccg accctgtgac gttgtagtgg ccccgcattg
    86701 ccatgatgct gaacttcgtg aactcgttga ggtccttcgt gagcatgatg gcattgtcga
    86761 tgttgtggtt cttggagagc gactgggtga ctcccatgcc gaagaagatg atcccgaagc
    86821 gcccgctctt catcacctcg gcaccctcga tgatcttctc ccgcgggatg cctgcgaccg
    86881 tctcggggag cggctcgttc cggagtgcca cgcggaaagc agagaggagc tcgtagtcac
    86941 ggccctgctc gacctggtag tggtaatcgg caagcttggc cgtgtccgtg acccgtgggt
    87001 cgacaacgat cactttccgg ttcatatgcc ccttgttggt gaagaacccg cgggggaaca
    87061 cggagtaacg ggactggtgc cgggggtggg catggcaggg gttgcagccc cagaatatga
    87121 tacggtctgc ccggttcttt atctcaccga gcgtgcagct ggggattcca acgtcctgga
    87181 ccgctataag ggttgtgcca tggcagacgg tggcggtgtt gtcaacgatc gccccgactt
    87241 tctcggcaat ctcgtgcccg acgctctgtg cttcgcagct cgtggagctc cagccgtaca
    87301 tgaggggctt cctggcattg aacagcatct gagcagtgta ctccacggcc tcgtcgtacg
    87361 agacttcctt gtaagtgccg tctggctgct gcatccgggg cctcttgacc ctttcgggtg
    87421 cctgggcatg catgaacttc tcggccccga tggcacaggc attgtaaata tcttctatct
    87481 tctttccatc atctgagaca ataacctcga ggtcatcgca cagggttccg cagaacggac
    87541 agataacgtc agtcacagac ttggacatca ggcctcaccc ctgcatttct tctggacgag
    87601 ctggatggaa ctgagaaccg gctcgtttat tgcaggttct acttcaatcg ggacgccctt
    87661 aaaggtaggc atcccggtag agtaggtctt cgggttgacg accgagtttg cccagggacc
    87721 catggggatg taggcaaggc ccgggtgggg cccctgggtg gcctccacgg ccttgacaac
    87781 cacgctgccc cactcgctcg tgacccggac gttcgtccct ttccagatgc ccagtttctt
    87841 caggtccgat gggtccatct cgatgatccc gcaggctttg gtgtaggcgt ctttctcctt
    87901 gccgccttcc atggccacac cctggtggat ggtgcggccc gtaatcaggt tcagtttcag
    87961 tttggccaag gtagatcccc cgggaatcag cgcccgatct ctttcagcgg gctggggcca
    88021 aggttcgtga tggtatcgac aacgtccttt accaccacgg cccacttggc tccctcggat
    88081 gcagagacaa atgtcatgcg cagccgcttg tcttcgagcc cgatgttccg gagcaggctc
    88141 tttaatatga acatcctctt tgccgccttg tagttccctt caaggtagtg gcagtcaccg
    88201 aagtggcagc cggagacgag aacgccgtcg gccccgtcca cgaatgcctt catgatgaag
    88261 agagggtcga tcctgccggt gcacatgacc cggataatgc ggatgtcggg agggtactgg
    88321 gtacgggcac tgcccgcaag atccgccccc gcgtacgaac accagttgca gatgatgccg
    88381 aggatcttcg gtttccactc ctgctcggcc atcactgttc acctccgagg aggaacgcat
    88441 ctatctgggc cacgatctgg ggcgtcgcaa agtgctgcat ccagatggcg ccgccggggc
    88501 agaaccctcc gcaggtaccg caacccttgc acttggcctc ggtgacctgc atgaccttcc
    88561 tgccttcctt ctcgacgagg gagagtgcct ggtatgggca gaggttcacg cacatcccgc
    88621 agccagcaca cttctcctcg atgcactggg caaagtacgg ctcgagctca acctcgccca
    88681 tgtggatcgg gatacttgcc gcggacgcgg caccttcggc agaagcgacg gtgtccggga
    88741 tatcctttgg cccctggcac acgccggcga ggaagacacc ggccgtcgtc gtcccgcagg
    88801 ggttcagctt cgggtgtgcc tcgagcagcc agccatcgag agagcaggaa acaccaaaga
    88861 gcttgcgcgt cctgtcagta tccgccgagg gctgcactgc tgccgcgaga acgaccatgt
    88921 cgacctcgag tttcatgggg cggtcaagga gcgtgtcgtc tgccatgacg tacaggttct
    88981 tggtaaccgg atcctcgagg acgttggaga cacggccgcg gatgaacttg gcgccctcgt
    89041 cctggatgcg gtagtagaac tcctcgtaca tcttcccgaa ggaccgtatg tccatgtaga
    89101 agatgtaggg ctggcagcca ggtatcttct cgatgatctg gtgggcatgc ttgagggagt
    89161 acatgcagca gaaccgcgaa cagtagggct tgcccactcc cgtattgtca cgggaccctg
    89221 cacagagcag gaaagcaacc ttctttgggg tcttgccgtc gcttggccgg accaggtgtc
    89281 ctccggtggg acccgacgca cagatgagcc gctcgaattc gaggctcgta acaacgtttt
    89341 cgtacttctt gtatccccat tcttccttct tctcgatggg gaagatgtcg tacccgagtg
    89401 caaggatggc tgtaccgacc ttgaccttga cgagttcgtc cttcatctcg agatcgattg
    89461 ctttcttctc accgcatgcc tcgacgcaca ggccgcattt cacgcagctg tcgaagtcca
    89521 cggtatagat gaggggcacg acctgggggt ggtagatata gatggctttc cggggtttca
    89581 tccccatctc gaaggggttc ggcttgataa cagggcagac tgtgtcacag tcgccgcacc
    89641 cgttgcagcc accgcccacg attccccgtg cctcggcctc tgccggtgtc aggacaccgc
    89701 gtgccttctt ccggatggtc acgtcgaagt tcccgatgta tccctcgacc tcctcgatct
    89761 cggagtatgt catcagctcg atgttcgggt tcctgccgac gtccaccatc ttgggcgtca
    89821 gaatgcactg ggaacagtcg agcgtcggga atgtcttgtc cagctgggac atgcggccgc
    89881 cgattgtcgg ggacttctcg acgaggtagg tcttgatacc ggcattggct agatcaagtg
    89941 ctgcctgcat tccggcaact cccgcaccaa cgacgagggc agccttcgtc acgggcacgc
    90001 tcttggggac gaggtcctgg aggagtgcgg ccttggcgac agcaatccgg atggcatcct
    90061 ttgcctttgc ggttgcaccc tcgcggtcat gcatgtgaac ccaggagccc tgctcgcgga
    90121 tgtttgccat ctcgaaccgg aacgggttga gtccacccgt cttcgtggca gtcctgaacg
    90181 tgggctcgtg gagacggggg gagcatgcgg caaccacgat accggtgagc ttgtgttcct
    90241 tgatgtcttg ctcgattttc ttctgtcccg gagtggaaca catgtactgg tagttgtcca
    90301 cgtgtgccac gttcgggaga gtctttgcat attcctggac ggcaaggatg tccacggacc
    90361 cggcaatatt tgtcccgcag tgacagatgt agacacctat ccgtgcccct tttccgagat
    90421 ctttatcggg ggatgtggca gcgggtgcgg gtgcgtgtgt ggccttcgat acagccttct
    90481 tggtgtcctt ctttgcagca ggctctttcc tggttttctt ttcagccatt ttccacctcc
    90541 cttcagagca ccttcttcaa gaatggctcg cagctgattg catgcaggtc gagggcaagt
    90601 tcctggggtg tcattccctg ggcgaggccc agcagttcac agtagtggag caccggcagg
    90661 ttgtatttga ccccgaactt ctcctccatc tcgatctgcc cgcgatcgaa ctggagctgg
    90721 cagaacgggc agacctcggt aagggcatcg acaccggcct ccctgaggtt gatcatcttc
    90781 tcgttggtga tgtcgaggga gtgcacgagg tcgtacccgc ggacgccacc cccggctccg
    90841 cagcagagca tcttgtttct gtattcgacc ggttctgcgc cgagggccgc gaccatctcc
    90901 tcgagccagg tggggtgttc ggtcgttcca aagtgccttt ctttgcgggg tttcatcagg
    90961 tgacacccgt agtggacggc aatccgcgtc ccggtgagag gaaccttcac gctgtcgcgg
    91021 atcttgtcaa caccaacgat attagggtca tagaagagct cggcgaggtg ccatacatcg
    91081 atggtcccct tgaactccat gtcgataccc ttgaggacct cgttgacacc gtcacggagt
    91141 tctttgttgt gcttgagctt atggttgacc tcccagatgg acttgtagca cccgttgcag
    91201 atcagggcaa tgtccttttt catctgctcg gcgagcacga ggttccgggc agccatggca
    91261 taccagacat tcaggtcgat agacccgaat gctccgggag cagggcagca gctggccccc
    91321 tcgagatcga ggagcttgat tccgagtctc tcggcggtct tgtaggatgc ggcctccgcg
    91381 ccggggtacc ggttgggagc aatgcagcca aggaaaaatg catattcacg catgggctct
    91441 catccctccc tctctttgac aatccggtcg gcattcttct tcagttcaaa gtaatcaagg
    91501 atgtactgga ttcccttgat gtactgtgca aaacggtgcg ttgtcggggg ttcagggtga
    91561 agtcccagtt tcttccgggc agcacggttc acgtcgttat tgggaacacc gtggcctgtc
    91621 gtatagatgg cctgcacggt cttgaggaag ttcaccggta tgatgtccct cttgaatgca
    91681 aggttccgca tggccatgat gacgtccgtc ggggcgatgt cccgcgggca gcggtcggtg
    91741 cagctgtagc aggttgtgca gagccagagg tccgggtcgg tgagtgcttc ctcttccagc
    91801 ccgaggagtg cacgccggac gaacttccgg atgcggtacg agctgcgtgg tgcagagggg
    91861 caggacgccg tgcatgtccc gcactggtaa cacatgtgcg ggatggtcat cgagatcttc
    91921 tcgactgtct tcgtgaactg ggggtttgta tcctcctcgt agaggcgggt atccctcaat
    91981 ttcttctcga gtggttcggg gtatcctttt gttctggcca tgtatggtac ctcacgcctt
    92041 ctccatcatc ttgagctgga cacttccggg ggtctcctct ttcactttcg aggtccgcgg
    92101 ggtgcagagc ttctccttga tcttcttgaa gaggtcggtc tccttgccct ttatccggat
    92161 acctgtccgg tgcagcctga tgatgtcctc gccgggacag gcgttcacgc aggcaccgca
    92221 caggatgcaa tagtccttgt ttacggcaat ggttggctcg accttgccct tcatctcgct
    92281 ggccttgaca ggtgtgggca ggtagattgc gtttgcaggg cagacctcga cgcacgtgga
    92341 acagccgccg gggcacttct ccgggaagaa ctcgatatca ccctcgaaga gcttctcgac
    92401 ggtaatggcc tcggtcgggc agttgcggga acaccaggtg caggtgcagc acatcttctg
    92461 gtcgatgtcc acctggccgg ggagcttctt accctcgatg acctcgcgtt cgacggtgat
    92521 gcattcctcc gggcagagct cgacacaaac cttgcatgca tcgcagcggg tctcgtccca
    92581 gacgacttcg ccctcgacct ttccggtctc ggctgtgaag ggcttgtgct tgacggtgat
    92641 tgccgggcac acggcgccgc aaatgccaca gagcgtgcat ttctcatcgt caaccttgaa
    92701 ggtggtcttg ctcttgaggg cctcctggcg ctcctttcca tcctcctttg caccctcgta
    92761 gacgggaacg tcgcggatga ttgcctcgcg ggggcacacc tcgtcacaga ttgtgcacct
    92821 gacgcatttt tcatcgtcga tgtctgcaac catgtcatac tgcgggaacc cgtccttttc
    92881 gacgatggga aggcgctcct cgccatcgat cttgagggtc agggcgttga acgggcacat
    92941 gacaacgcat acgccacagt aggagcactt gacctcatcg atgtcgacgg gggatgcata
    93001 cccgacagct cccctccggg tggcacccac gagcccgagt gcgattgctt cttcagggca
    93061 ggcttcgacg cagattccac acccggtgca tacctcggag ttgagcacca ggttgttgac
    93121 ctgctggagg agccgctgtt cgcagatgac gttcatgcca tcccggatct tcttgaattt
    93181 tggaaacagt gtcatttggt atcctcacga atctcctgta gtcacacgtt cataccttgg
    93241 cctcactggg cactgctcca cggcctgcca gccgtatcac atcgtgcggg caggcttcaa
    93301 cgcacacgcc acagccggca cacagttcct gcttgaaatc aagaaccatt gccttgccat
    93361 gcctcacctt gtagatcttt tcattggtcg ccggatccac ggtgaagagt tcgagtgcat
    93421 caacagggca tgccaccaca cagttgttac agccggtaca ccggtccatg ttcacgtgca
    93481 atgcaaatgc cattcttttt cacgcaccag ctttcaatcg attgaaaaat cgactaaaaa
    93541 aacaatggtt aacgtatata gataaacctg tctgattttt ccgaaaggac gtgcaagcag
    93601 cgagtattta atgtaaaaat gtaaaagtta acaaaaacaa tatgttaata taatgtgtat
    93661 aaaaaaaccc ggaaaattgc tgcgtttttt ccattcccgt ctgacaagaa aatcaaataa
    93721 aaatccttat ttagacaatt accattggta aagaaacttt aattccgatc atgaatccgg
    93781 ggcatcttcc cgtgatcctc aaacagctaa tgggatacca cggctgatgc cggtggggga
    93841 caagtatttc gaaaatttct tctgcaatca tcatggtacc ccttcacgaa aggagaatac
    93901 ttgcatgcaa ttgaacggag taaccattga cgacacgtat gcagaggcat ttccgacatg
    93961 gattgcccgc gtcatcatca ccgcagcaac cctcgaatgg gcaaggaagg ctgccaccga
    94021 ggcaacagga tttgcgacat cggcgatcgg atgcccctgc gaggcaggaa tcgagtgcga
    94081 actctcccct gacgagacgc cggacgggcg ccccggtgtc gccattctca tctgcgcagg
    94141 gaaaaagaag ttaaaggagc aggtcgtgga acgccttgca gagtgcgtcc tgacatcacc
    94201 taccacggcc gtcttcaacg gtctcctgaa tacagaggaa aagatacctg tcaaactcca
    94261 cttcttcggt gatggatacg agtaccagaa ggaggtcggt ggcaggaaat gctgggtcat
    94321 acccatcatg gaaggggagt acgtgggtga agaagagttt ggcatcgtga agggcgttgc
    94381 cggtggtaac ttctttgtga tgggcgagaa ccagatggca gccctcatgg gtgcacaggc
    94441 agcctcggat gccattgccc gggtccgcgg ggttataacg agtttcccgg gcggaatcgt
    94501 cgcaagcggc tcgaaggtgg gctcaaacaa gtacaagttc atgcctgcga gcacgaacga
    94561 gaagtactgt cccacgataa gggacaaggt tccggacagt aaggtccctg ccggagtcaa
    94621 tgcggtctac gagatcgtca tcgatggcct tgacgagaag gtggttgcgg aagctatggc
    94681 caagggtata aaggccgcag tcagggtacc cggcgtgaag ttcatcagtg cagggaactt
    94741 tggcggaaac ctcggtccct acaagattga actccataaa atcctctgat ctttttcttt
    94801 cttcgctatc ccgtatccga ggagccgtgt cccgtccatc atgcaggggg tatcttctcc
    94861 cggaaaaacc gggtcctcat tcttaaagcc catttccgtg gcgggatgag ggataatccc
    94921 caggtcccgc ctttatggga aaggatcgaa ccatataaat acctcattgc cggatatttt
    94981 gttcacgaaa ttttcggtga caaaatgacg gggaccatct ctccttttcg gatcgtggag
    95041 gtgctgcgtt gacgggaagg gacgtccccc tcctcgagga cccctacatc atccggtacc
    95101 ccgagatcgt ggctgtaacg gacaaggagg gcagacaggt cgaactcgtg gaattctttg
    95161 agtgcacggg aggtgccatg tgggtccagg aacactatgc caagagtccc cttgtccggt
    95221 ccgtgcgcac cgtgggatcg agtacgcgat acatccttga accggggact gtcgacctgg
    95281 accttgtcgg ttcccgtttt cctgccggga tatcaggagt atcagttgag ggagacgaga
    95341 ttgcaatatc gtacgtgggt cttggcggcg ggggtgtcgg ggcttcaggc tgtcgttccc
    95401 ttgcaggggg agtcatcagg tcacgcgctg acccctcagg cgggggtaaa aaagcagggg
    95461 ctacggtctg gctgccccgc agggaacgtg tcctcatcgg tgttgacgat acggatacac
    95521 cgcaggaggg ggccacgtgg actctctgcc acaacatcgc ccgtgcagtc caggacgagg
    95581 actcacgata cctctcccac acgatcgtgc agctctttcc ggtcccctac aggacaaaaa
    95641 actgcgttgc agttgtctgc gagtttgcat cgcgtaaccc cgaccgcctg gtatccgcct
    95701 tccaaaggct gcttgccacc catacgctct cttcggagac gggcatggcc gttttccggg
    95761 gttttgaccc gggcccgctc ctcggggagt ttggctgggc cgtcaagcgg ggagaggtca
    95821 gccgcgagag gctcgatgcc ctcggaaggg atggcctcga gttcatcatg aggggcaggg
    95881 gtctcatcgg cgctgcagca tccatcccct tctatacccg ctacaaggag gcgctgagac
    95941 tgtgcgatgg aaagaattga aggcagatct cctctccgtc ggaacggcac gtcttgcagg
    96001 cgaacctgcc gggaaatacg tttcccgctc ggcagcaggc cccggagcag gcggcccggg
    96061 atctgtcttc ttctccctgg aaggaaagag ggtccggctc tcgcttgatt cggaaagtcc
    96121 ggtcctgatc acccacaccg gcgaagggag agccgtgctc gagtacaggg gccgggaggt
    96181 cagggggagg ctcgaggagg ttgctctcca ttgcccgcgc caggcgtacc tgacggtaag
    96241 cagcgggtgc atcttctcgt gccgttactg cggcgtgccc gggaatccca tggagaggaa
    96301 gtccgtgaga gaaatcgtgg aattggtcag gcaggttgca gaccgcgttg atgccatctc
    96361 cctcacaagt ggagttatcg ggtcagttga ggaggaagag cggtatgtcc ttgaggtagt
    96421 caggcagctt cggcagcagt tttcgcttcc catcggcgta tcgatctacc ccacggaaag
    96481 gacaccggag cgcctccatt cacttggtgt cacggaggta aaattcaacg tggaaacggc
    96541 aacagacaac ctctttgagg agatgtgccc ggagctctca cgggatgcca tctgggacgc
    96601 cctctcgcga tccgtccctc tcttcgggaa aaaccacgtc ttttccaaca tcattatcgg
    96661 gcttggagaa acagatgggg aggctgtatc atgcatcagg agactggccg gcatgggtgt
    96721 catccctgtc gtccggccac tcactcccgc agcggcatgc aggaatctcc cccgaccctc
    96781 acaagaacgg ctccttgccc tcttcagggt gcattcggac acactccggg acgccggcct
    96841 cgacccgcgg gaggctgtct cgatgtgtgc ggcctgcaca ggatgcgatc tcgtacccgg
    96901 gagggacgat tcatgaaagg agaagaagca cttgcccgcg caattctcac tgcaacggac
    96961 aggaggtaca ccgttcccgg gtatcccatt accgggcttg ccacccggtg caacgcggaa
    97021 atggtcgtca acgagaagac cggcctggaa tatgcactcg gtgactccct gtcagggaaa
    97081 cgcgcagcac tgattgtcaa gaacgtcggt gtcaacgcat gcgttgaccc gctcgtacag
    97141 gcgactgcac agggtctcat cggaggtgtc ctcctggtcg cgggcgacga cccggcagcg
    97201 gcgggttccc agacgtccca ggatacccgt atcatcggtg aactggcaga gatccccgtg
    97261 ctcgaaccgg gcccggagag ctgcttcagt gcagtcgaag ccgctcttga agcttcagag
    97321 gagttctcac gggttgccat gctgcgggtc actccggcgc tccttgaagc agaggcgacg
    97381 ggcgacccgg ttccccgccg ggataagaag ggcagccttt cggacaggag ttataccatg
    97441 cacggaagag tgactgcatc gcgccgcctc tttgcccgga tgcaggaatg ggcgctccat
    97501 tcaccactca acacatggca ggggggtgcg gccggaatag ggccacgccc cggtgaaacg
    97561 cgggtcgtga cggtattccc gcctccaagt attctcggtc agtacaccga gatcagggag
    97621 gagggtcttc cttttgcagg ggatcattgc cgccaccggt ttttacccga ccctgcggaa
    97681 gaagaacccg agactctcga aagcaggggt tactaccgga cattctgccg ggactgtccc
    97741 ttttggccgg taatcgctct catgaaggaa gaggggttga gacccgtgtg cgatgcggga
    97801 tgcgtcgtca tggctatgaa cccgccatac cgtgtcggcg tggcaagtta cggtatgggg
    97861 tcttcgatcg cggtggcagc acggagcacg ggattcgcac tcacgggaga ctacgcactt
    97921 ctccacagcg gcatcaatgc cctcatcgat gtatacgaaa agaggatccc cctcctctgc
    97981 gtcgtgctgg acaaccgctg tgctgcaatg acgggaaagc aggcttcgat acccatcgac
    98041 ccgtacctgg aatgggcacg accacactat accgatgcat cggagatcgg gaggctccgc
    98101 gaactcttcc ggactgcgca gcggccggga gtcattgtaa tcagggggga atgcccggag
    98161 gggcaggacc atgaaatcgt ggcatataga aatctgtgat gtgactcttc gcgacggtga
    98221 acagaccccg ggggtctctt ttacctgcga ggagaaggtc aggatcgccg aggtcctcga
    98281 ccagattggc gtggaggtga tcgaggcagg gttcccggcc acctcgagtt acgagaagag
    98341 gtgcgtaagc agcgtagcgg cgctggatct cgatgcacgt atctgctgcc tggcccgggc
    98401 gcggaaggga gacgtcgatg cggccatcga cgcaggtgtt gatatggtga gcatcttcat
    98461 ccccacgtca gagctccacg tccgccacaa gttccacgcc ccgcgggaaa aagtcctcgc
    98521 cgatgccctc gagatggtgg actatacacg cgaccacggt ctccaggtcc ggttcgccgc
    98581 agaggacgcc tcgaggactg atctgccctt cctgctcgag gtctacaggc agggagagga
    98641 acatggtgca gacctcctct cgtttgccga taccgtggga gccctttctc ccttggaaat
    98701 gtacaggatg atgagaaaga tagtcagggc agtgaaaaag ccactctgtg cccactgcca
    98761 caacgacatg ggaatggcca cggcaaacac gattgcagcc gcccaggcag gcgcatttca
    98821 gctccacaca acggtcaacg gcatcggcga acgggcaggg aatgctgccc tcgaggaagt
    98881 ccttgtcgcc ctgtacatga agggaaatat caggcgctac gacctctcgc acctcacgac
    98941 actctcggcc atggtcgccc agtactcggg gattccggtc gacaagctca aacctgtcgt
    99001 gggcgagcat gcattccgcc atgaaagcgg catccatatc gccgcgattc tggaggaccc
    99061 gtccacgtac gagtatttcc cgccgggact cgtgggcgcg acccggaagt tcacgctcgg
    99121 aaagcatacc gggaagaaag cactcgagca cgaggttgca cggctcgggt actctctccc
    99181 ggaaaaggat ctctgccgcg tcctcgagct cgtcaaggac aggggggaaa agaaggtcga
    99241 gctcacggac gagaccctga tcgacctgat caagatggtc atggggggtc caccgctgtg
    99301 accacgctct cggaacgtat cctcggggca ccggcaggaa gttacgtgga ctgcagggtc
    99361 gacaggtgtt acgtccacga cggcacgggt gtcctcaccc tcgaggctta tcaagccatg
    99421 caggcagaaa gaatcgcccg aagggaccgg acatacgttc tctttgacca catcgtccct
    99481 gcgaataact cggtgacagc aggactccag gcggaactgc gcaggtttgc ccgggaccgg
    99541 ggacttccct tcacggacgt aggcgaggga atctgccacc aggtcatggg agaagggatt
    99601 gtactgcctg gcgagatcgt tgtgggtgca gactcgcata catgcacgct cggtgcgttc
    99661 ggggcatttg cgacaggagt tggtgcaacc gacatggctg ccatatgggc agacggtggc
    99721 acgtggttcc gcgttccgga gacaatcgcg atctttctct ccggctctct gaaggagccg
    99781 gcagaggcca aagaccttgc cctcacatat gtcagccgcc tttccatgga cggggccacg
    99841 tacaaggccc tcgagttcgt gggggacggt gtgcagtcac tctccatgga gtcccgcatg
    99901 acactctcga atcttgcggt ggagacaggg gcaaaggccg gccttttcta cgccgacggg
    99961 acgacgtgtg cataccttgg ggactatggg cattccgtca gcccgcaggt tcccgatgaa
   100021 agttcatacc cgcagagact ggagatcgac atctcggaca tcgtcccggt cgtggcagta
   100081 ccgccccggg tcgataccgt ccggcccgtc ggggatctgg cgggtctccc gctcgaccag
   100141 gtctttgtcg ggacgtgcac gaatggcagg tatggtgatc tggagcggtt tgcccggatt
   100201 gtccggggaa aaaaggtcag ggtccgcacc cttgttgcac ctgcctcccg gcgcgtcctt
   100261 gcccgtgcat ctgcgacggg ggtcctttcc tggctgatcg aggcagggtg caccatcctg
   100321 ccgcctggct gcgggccgtg tcttggtgcc caccagggcg tcctcggcga gggagaggta
   100381 tgcctctcga cggcaaaccg gaacttccgg aaccgcatgg gtgtcggtgg ggagatctac
   100441 cttgcctcac ctgcaaccgc tgctgcaagc gcactcgcag gagcccttgc agtcccggag
   100501 gtgccgcggt gaaggtagag ggacctgctg tctgccttgg ggctgacatc gacaccgaca
   100561 tcatcatcgc agggcggtac ctgcgtacga aggaccgttc ggtatgggcg acacacgtct
   100621 tcgaggacat ggatccggcc ctggcttccc gccttcgcgg ggctgtcatc gttgcgggga
   100681 aaaattttgg ttgtggctca tcgcgagagc aggcagcgat agcactccgg gaagcgggag
   100741 tccggtgcgt gattgcaccc tcatttgcga ggatattctt ccgaaatgcc atcaataccg
   100801 ggcttccggt gatggagtgt gaatgtccct gcatggaggg gaaaaaagtc gttgcagatc
   100861 ccgtttccgg gagaatagaa ataggggacc gggtattctt cgcacgcccc ctttccccgc
   100921 ggatgctcgg gattctctcc gcaggtggcc tggtggaata ctggaggaag aaaaggtgat
   100981 cttcccgcgg gagtgcaagg ttgtcggtca tgcgggagac agtccctgcg gtgagaatgt
   101041 gtatttcctc acgaaattcc tcctccggga gacaaacggg ggtatggaac tccttgaggt
   101101 cacgacagat cccctcgcga ccggcatgat gcgacccgtg ctggagacac gcgtccttgc
   101161 ggttccggag gaggtgatgg tgtatccccg gcgcgtccaa atccataaca gggcacgcct
   101221 cgttgagctt gcactcgaaa gcggcaagag atgcaccgtt tttaccgggc acgacgagca
   101281 catgacattc gtccttgacc ccgatccggc ggcgttcctg aaaatccatg tatacgatat
   101341 cgtcccgccg cgcccgagcc tctcttcgac catccgcgaa ctcgaggagg cggggatgtt
   101401 cggagaactc gatattgcct tcatccacac cctccgggat atttcgcagg tcgatgctga
   101461 cgttttcccc tgccgggcag caggtttttc gcggacactt gacgcggacc ccgtctcccg
   101521 gcacgagaaa gtcgccggtt gcctgaccgg gtcgcaactc gtacgggagt gttatggcga
   101581 aggtatcgag gtcatcgata tatgtcccct gcggatggtc agggaggaac ctttcatcac
   101641 gcgttgctgc aggaaggaga gggaaggatt acggatggtt aatggaaaga atgggatcgt
   101701 tgtccactgg ggtgccgggc ctgcggagat atacagggcg gttataagcc ttgtgcgggg
   101761 gaaaggggaa ggatgagaat tgcagtcgtt gaaggagacg ggatcggcca tgaggtcatc
   101821 ccggttgcaa aacgggctct cgaggtcctt cgcccggatt tcgagtttta ctccgtggac
   101881 gtggggttcg ggaagtggca gcgctgcggc gaggcaataa cgtcacagga catggaagac
   101941 ctctcctctg cagatgcaat cctttttggt gcgatcacca cgcctcctga cccgggatac
   102001 cgcagcgtca tcgttcagat caggaagact ctcgacctct atgcaaacct cagacctgtc
   102061 tttgggaaag gttttgatat catcatcgtc agggagaaca ccgagggact ctactccggc
   102121 gtggagaaga tcgaagagga ctcggcgtgc acggtccgct gcatcacgcg gagggggagc
   102181 gagcggatcg cacgatgtgc gtgccgtctc gtaaaaaaac gcagggagct caccatcggc
   102241 cacaaggcaa atgttctcaa ggcagatgcc ttcttcaggg acatctgcat cgcagaggcc
   102301 cggaaggccg gtgtgccttt ccgtgagtgc tacatcgatg cactttgcct cgacgtcctc
   102361 cagcaccccg agaggtacga cgtcatcctg accgagaaca tgttcggtga catcatctcc
   102421 gatgttgctg ccttcctcgt gggcggcctc ggtgtattac caagcggtaa catcggcgac
   102481 cagcacgcgc tattcgagcc cgttcacggg agcgcccccg acattgccgg aaaaaatgta
   102541 gcaaatccca ttgcggcact ccggagtgcc ggcatgctcc tctcttacag tgcccgcgac
   102601 cctgtatccg cgcagcggat cgaggaagca atcgggcgga tccttgcgca gggaattcgg
   102661 acgcgggacc ttggcgggaa tgcaacaaca acagagtttg gggatcacgt catcctggaa
   102721 ctggagtcca tgaaccgggc atgatgagtt cccccccttg ttttcttcaa acaggggcgt
   102781 atgggtattt tatatatact gcgttcaata attgcaaatg atgcatatgg ggagaatcct
   102841 cctcgtcgat gactcggaga tggcgcggtt ccttctggcc cggttcctta ccggaggagg
   102901 gcacgagatc gtcggggaag cggcaaacgg aatcgaagca atcgagaagg tcagggagac
   102961 tgcccccgat ctcgtcatcc ttgatctcat catgccccag atgaaaggta tccagaccct
   103021 cgaggagatc aagaaggtga gcccgaagac gagcgtcgtc atctgcacgg gtgaccacca
   103081 ggagtatacc gtcagggagg ctgtcaggaa aggggcatcc ggattcatta tcaagccctt
   103141 tgacaaggac atcgtcctcg atgaaataaa taccgttctt gccgggaaac agccctgatc
   103201 ccccgaagtg gtccttccct gcaagtaacc tccaaagagg ctaacctttt ttcccatcct
   103261 tgcgatccct ctcatccttc agacgagagg gtttttccgt tcgggccctg atattttttt
   103321 aaaagtctgg ttccagccag gagataaggc aggtgttgta aggtggtcag ggtcggtgtt
   103381 cacatatcga tagcaggatc gattgcacag tcggtgggac gggcacaggc aatctcctgt
   103441 gacactttcc agatattctc gaggaacccg agaggctgga agtataagga gattcctgtg
   103501 gaagaagcag aagcattccg atcagccctt gccatgtcag ggatcaaacc tgtctttgac
   103561 cacatgccct acctgccgaa ccttgcaagc ccgaaggagg atatttacga aaagtcctgt
   103621 gcagccctct ctgccgagct tcaacgatgc ggacagctct ccattccctt ccttgtcaca
   103681 cacctcggcc atcacctcgg ggagggggct gatcccggga gaggaagggt tgttgaagcg
   103741 ataaacagcg ccctttccgg tgcacctccc ggggtcatgc tcctcctcga gaacacggca
   103801 ggggaaaaaa acagcgttgg aagcactttt gaggacatca gggcagttct cgatggcatt
   103861 gagtatcctt cgcatgtggg agtctgtttc gatacctgcc atgcatttgg ggcaggatac
   103921 gagcttcggt cgccggaagg gatcgaggag actcttgcca cgctggacga ggtcatcggg
   103981 caccccctcg tccgcctcat tcatctcaac gattcccgcg gagagagagg gtcgggcctc
   104041 gaccgccacg agcacatcgg ccttggctcg atcggcgagg aaggcttttc tctcatgctc
   104101 catactgact tcttccggaa acgacctttg atttgcgaga ccccggttga cgatcgcaga
   104161 gatgaccgcg gtaatatcgc aaaggtcagg gaacttgcgg gataaacaat ctgtggcatt
   104221 catactcgtt cccccctgcg gttcccggtt ttcgccgcat gatattaaga gtgcaccaag
   104281 cccattggta catgcgtgaa agccactttc gacggtgaac atgtccgcct gggagcggag
   104341 ggaaagagcc tctacgagca gagcggatat ggccggccgg agagggacgg gctccggctc
   104401 gctcccgagg aagcgctcta cctcctccat cgcggccgaa tcgaggttcc cggccacaca
   104461 ttcgacagcc tgctcgcact ttttgcggcc cgcccgaact tcatgcgttc cttcctggtt
   104521 tatcgtgaca tccgcgaacg cggctatgct gtccagacag ggccccacga tttcagggtt
   104581 ttccgccgcg gccagaagcc cggcagggga ccctcccagt acagcatctc agtcgtttcg
   104641 gaaagggacc tcatcgtctt tcaaaaagtc atcgaagaag tcaccgcctc ccggaacatc
   104701 cggaaacagc atgtacttgc tgcagtcgac gatgagaacg aacttaccta ttacgaggtg
   104761 aagatacagg ttccggaggg tggaatggca ggtggaacgg tgccgcacct ggtaggagaa
   104821 cttgtcggaa ggaatgcaat cgtccacaca gaagggtcac gatgcccggg tggctggggg
   104881 atgcagctgg actcggacag gctcgtactt tctcctcttg aaatcctatg cctgcttaag
   104941 tcaggaaacc ttgtgctcac gggcgaaggt gcagggatgg atccggacac cttcgccagg
   105001 accgcccggg aatccgatgt tgagttccct gaaaaaatgg aagtctacga agatctcagg
   105061 aagaaaggac tcgtcccaag gacgggatac aagttcgggc accacttcag ggtttacacc
   105121 gggaggaaga tccattccga gatgctcgtc caggcacttc ccggcggcgc cgcgcttccc
   105181 atgagcagca tatccaggtc tgtccgtctg gcccacagtg tcaaaaagaa gatgttgttt
   105241 gcatgcatac ataacggggg aatccgctac gtggaatttg cccgcatcaa gctctagggc
   105301 aggaagataa tggaaacacc gataaacccc tggtcctccc agcagacaga tgatatcgag
   105361 aaactcttct ctctctttgg aatcgaacat ataagcacca tcgaaggaat actcccaaag
   105421 gttccgtcgt ttatctcccg cggtgtggtg gtcggtcacc gggactacag ggtcattgcc
   105481 gaggccatca gggacaaaag gcccttccat atcctgacgg ggttcatgcc atcgggtcac
   105541 cctcacctcg gtcacctcat ggtcatgaag gaagtggtct ggcacgtgca gcagggcggt
   105601 tcggggtaca ttaccattgc cgacagggaa gctcatgctg tcagggacat ttcatggcaa
   105661 caatgcgagc attttggtaa ggagtatctc cagtgcctct ttgccctggg atacagggga
   105721 cgtacctatt ttcagagcag gaacaacgcc ctcaaggacc ttgcctttga agctgcaacg
   105781 agggtgaact tctccgaact ccaggcaata tacgggtttt cggacgagac ctcccttgca
   105841 cacgcggaga gcgtgatcac gcaggttgcc gacatcctct tcccccaggt ggacagttat
   105901 ccggcgccga cactggtccc ggtgggtatc gatcaggatc cgcacatccg cctgacaagg
   105961 ggaatagccc acaagctccg gatgttcaca gtcgaggaaa gggatggcta catcagcgtc
   106021 aggtcaaaga atgcacccga agaagccctt gccgaggtgc accggaagtt cccgggctcc
   106081 cggaaatacc agggtcacgt tgacattccc cgcgcaggct gtgcagaagt gagtgccgag
   106141 gtcaggaaga tagagatagc ccatggcggc tacgggttct atacgccgtc ttcaacgtac
   106201 cacaggttca tccccggtct ccagggcggg aagatgtcaa gcagcatacc cgagagcacg
   106261 atcacattct ccgagcctga cgacgtggta aggaagaaag tgatgggagc ttttacgggt
   106321 gggcgggcta cactcgccga gcagaaagaa ctggggggtg aacccgaaaa gtgcccggta
   106381 ttcctcctca acctcttcca catggtggat gacgacgctg aactggctga aattcaccgg
   106441 cgctgccggg gaggcgaact gatgtgcgga caatgcaaga aagaaacaac agaacgtgtg
   106501 cttgccttca tccatgactt ccgggaaaag atggaagcat cagcacacat ggtgaaggtg
   106561 gaatgagatg gatctctccc cgaatgaaaa gagactcctc gtgctcctcg agaaggtaaa
   106621 aacagcagat ccttcagcac ttgcggcaga aatgggtgta tcccccgaat cagtcatcca
   106681 gtatgcttac ctgcttgcag atcgcgggct ctgcagggtg gaaaaagaag taaaaacgac
   106741 atattccctc acggaagagg gacagaggta tgcaagcgaa gggcttcccg aacggcagct
   106801 cctcggaagt tttaacgaaa agatacctgt acaggaactc acccgtcacc cccttgcccg
   106861 gatcggaatc ggacagatga agaggaaggg ctgggtcgtt gtccgcgggg gtatggtgga
   106921 aaaaacgggg aaggatgctc cgggagaaga cgaactggca ctccgggatc tttcgcgggg
   106981 tggaccgggc cttgcagagc tgcgaaggag gaacctcgtt accgagaacc tggaaacccg
   107041 gtacaggatc tccgtgacgc cggaaggtct cgactgggca cgtcgcggcc tcgacatgtc
   107101 agaagaggcc ggaacactga cccgggagca gatagtctcc ggttcgtgga agggcctgaa
   107161 gctacggaag tacagcctga aggcccctcc cagaaaggta tacccgggaa agattcaccc
   107221 gtaccagcgc gtgatcgagg agatgcggca aatccttctg tgcatgggat tcacagagat
   107281 ttacgggggt attgtccagt ccgcgttctg gaatttcgat gccctcttcc agccacagga
   107341 ccaccccgct cgcgagatgc aggacacgtt ctacctgaaa gagacgttgc ccctgccgga
   107401 aggatatgaa cgcgtgaggg atatgcacct ctttggggga aacacatcat cgacggggtg
   107461 ggggggccgg tggtcacgcg agaaggccga acaatgcgtt ctccgcaccc atacaacgtg
   107521 cctttccatc cagcacctcg cgacacaccc ggaaccgccg gtaaaagcat tctgcatcaa
   107581 ccgggtgtac cgtcgtgagg caatcgatcc cactcacctg cccgagttcg agcagctcga
   107641 gggtatcgtg atggacaggg atgtgacctt ccgccatctt ctcgggtttt tgaaggagtt
   107701 ttaccaccgg atgggatttc ccggcgtccg tttccgcccg ggctacttcc cgtataccga
   107761 accgagcgtt gaaccggaag tctttgtccc gtctcttggc tgggtggaaa tggggggtgc
   107821 gggtatcttc cgccaggagg ttacggcccc gtttggaatt acccatcccg tcctcgcgtg
   107881 gggtctcggc gtgagccgca tcgcaatgct ccggctggga ctctctgacc tccggctcct
   107941 ctacaagagc gatatcgggt gggtccggga gaccccttcc tggctgcacg ggccggatac
   108001 aggtgtgggg ggtcagaaat gccggtaatc aggctttact accggtacct ggagaaactg
   108061 gtcggtaccg acagggaaac catccttgca aacctcccca tgataggttc ggatatagaa
   108121 cgggtcgaag aagaccatgt ggacgttgag ttcttcccaa gccgccctga ccttttctct
   108181 gtcgagggtg ttgcccgtgc aatgagggga tatctcggga tagagacagg gcttccccgc
   108241 tacagcgtca cgccgtccgg gatagaattc tctgtcgacc ccggtcttgc gacgatcagg
   108301 ccatacctcg gctctgcggt catcaggaat gtcaagctcg acgaggaatc catcctgtcc
   108361 ctcatggggc tgcaggaggc acttcactgg gcagtcggaa ggggccggag caaggttgcc
   108421 atcggcatcc atgacctgga cgcggtaacc cctccgttcc ggtacatagc cgccgaaaag
   108481 tcacgtgcgt tcgtcccgct ggactttgat cgtgagatga cactcgatca gattctggac
   108541 gaacacccga aaggaagggc ctatgcccac atcgtcagtg atttcccccg gtaccccctg
   108601 atcgtcgatg ccagggacag ggtgctctcc ttcccgccca tcataaacgg ggaactcaca
   108661 cgtgtcacgc aggaaacaag aaacctcctt ctcgatacaa ccggaacaga cgagcgtgct
   108721 gttgcaaccg cagtcaatat tatttgtaca gcccttgccg ataccggtgc aacggtccag
   108781 agtgtcacaa tcggggggag ggagtgcccc tccctcgcac cctcggagag gattgtgagt
   108841 tcagacgatg catcagccct gcttggtgta ccactcgact ccacggcgct ctcatcactg
   108901 ctggagaaga tgcggtacgg cgccggacca gccggggtat cccacgtcag ggtcctgatt
   108961 ccctgctaca gggcagatat catgcatgac tgggacatct tcgaggacgc agcaattgca
   109021 tacggatacg gtaccttcga tgcggaaatg ccacggacat tcaccgtcgg ggcaccccat
   109081 cccgtgatgg cgatctatgc cgttgcaagg gaggttatgt ccgggctcgg gttccaggaa
   109141 gtactcccgt tcaccctcac gaacgagaga gttcttgcaa cgaagatgca gaggccgctt
   109201 aaggactcgg tcctccgggt gatgcatccc atctcggagg aacagaccgt tgtccggacc
   109261 gatcttctcc ctctcctcct ggagatgtgc cagctcaaca ggcaccggga actcccccag
   109321 cggctctatg ccgtgggtga cgttgtcggg ggaacgcata cctatccaag ggcagcctgc
   109381 gtcagcaccc atgcagctgc tgacttctcg gaagcatatg ccgtcgcgga tgcattctgc
   109441 cgggaacttg acgtcgcggt ttcggtggag gaatcggacg acccggcgtt tattccgggg
   109501 cgccggggaa atctcgtcag cgggggaaaa accgtgggtg tctttggaga aatacaccct
   109561 gccgtcctga acgcgtggga gctcgagcat cccgttgcgg ccgttgaaat tgaccttaca
   109621 gccgtaccgg gataccccgg gcagcaaggt actccttgac ctgccggacg gtcatctccc
   109681 cgtaatggaa gacgctggcc gcaaggcagg catccgccct gcccagcgcg aacccctcgt
   109741 agaagtgttc aagggttccc actcctccgc tcgcgatcac cgggatgccg actgcgtcag
   109801 agatcgctgc agtaatgggg atatcgaacc cgtttttcgt tccatcagtc tccatgctgg
   109861 tcagaaggat ctcaccggca cccctttcct ctgcctcgat ggcccaccgg acagcatcga
   109921 ttcctgtcgg gcggctcccg ccataggtca caacctcgta ccagcattcc ctgccatccg
   109981 ggagcgcgac cattgttgca tcagggttag gcgtgaaatt acgccggacg tcttcagcaa
   110041 gaacgataca ctgtgtcccg aacttatcgg ctcccctgtt gatgagagtg gggtcgttga
   110101 cggcgctcgt gttgatgctc accttgtctg cgccggcccg gagaatctgt tggatgtcgt
   110161 ctaccgaccg gatacctcct ccgacggtga ggggaaggaa gagctggtct gcagcgcgtg
   110221 tgatgacgtc gaggatcgta ccgcgggcct cgacggatgc ggcgatgtcc aggaagacga
   110281 cctcgtccgc tccctgttcg ttgtaacgct gggcaagtgc aaccgggtcg ccggcatcgc
   110341 ggaggcccac gaaatgcgtt cccttaacca ctctaccatc cttgagatca aggcagggga
   110401 taatccggcg ggtcagagtc atgagagatg atccgatggg atggattatc atgcttgtgc
   110461 acggtgatta cgccgggttt taagtcagtt gcaggttgat cccataaggg aatgccgggg
   110521 acacagaggc tgtcccgggc cgggatgtgt tgccatggag acagggaaaa agaagatcgc
   110581 gtgggcacgg cagtacatgc cggtcctcgc ctcgatcaga ggagagttcc agcaaaataa
   110641 gccgctgaag ggaatccgca ttggtatggc actccacgtg gaggccaaga cagcatgcct
   110701 cgtggaaaca ctcgcagcag ggggagcaga cgtgcatatc acgggttgta accctctcag
   110761 cacgcaggat gacgtagcgc gtgccctgga tgaggtaccg ggtgtccact gctatgcccg
   110821 gaggggagtc acagccggtg aatactatgc tgctatcgac agggtacttg attcgcaccc
   110881 tcaggtcgtc atcgacgatg gcatggatct tatccacagg ctccataccg tgcgaagaga
   110941 tctccttccc cacgtcgtgg gtggctgtga ggagacgacg accggcgttc acaggttgcg
   111001 ggcgatggcc cgcgaaggaa aactcgcgtt tcccgtgata gccgtcaatg acactcccat
   111061 gaaacgccac tttgacaacg tccatgggac aggtgagagt gccattgccg gcatcatgct
   111121 cacgacgaac atgctcgtgg ccggaaaggt cgttgtcgtt gccggttacg ggttctgtgg
   111181 ccgtggactg gcacgcaaac tgcatggcct cggggcaagg gtgatcgtga ccgaggtcga
   111241 cccgaggagg gctctggagg cttacatgga cgggttttcc gtcatgccca tggaggaggc
   111301 ggcaggggcc ggggagatat tcatcacggc aacagggaac acgtcagtca ttgcggaacc
   111361 tcactttgcg cgcatgaagt caggtgtggt ccttgcaaac gcagggcact tcaacgtgga
   111421 gattgatatc gggtggctcg agaagaacgc gactgcagtc acccggcggg acggtatcga
   111481 tacctatacg gtagatggaa aggacatcca tgtccttgcg gaagggcgcc tcgtcaatct
   111541 cgccgttccg aaagggatgg ggcatcccat cgaggtgatg gacctgagct tctccctgca
   111601 ggcactctgt gcactccaca ttgcccggca gggccggaca atgaaccccg gcgtccacga
   111661 ggttcccccc gaaattgatg aaacagtcgc agaaaggaaa cttgcttcgc ttggcctctc
   111721 catcgacaag ttgaccgagt tacagaagag ttacctctcg ggctgggaat ccgggacgta
   111781 gaggtttgaa ccccctcctc tccctttccc cgcatcaacc cgtcccgcaa ggacagtcct
   111841 gcagcaatag aggtattcct gtgcatatcc tgcgtatttt ccgaagtatg cccgcccaaa
   111901 gtcgctgatc ttgtcgtaag tccgaagatc cctgcattcc gggtagcagc gggtcatgat
   111961 cctctctatc cagacatcaa caggaaagga ttcccacttt ccgaatgcaa agaggagcac
   112021 gcagtctgca accttttttc cgacgccttt gagtctgaga aggttcgccc gtgctttggg
   112081 gaaggaaagt gcatcgatcc tctcctccca tcccgtgtct gccgcgagaa cccgggcagt
   112141 ctccctgaga tatccagccc tgtacccgag gctgcagccg ctgagcatgc acgtttccgc
   112201 tcctgcaata gctgttggcg agggaaatga gaataatccg ggatattccg gagaaagagg
   112261 agcacccagg ttttggcaca ggagatgcac tcttttcctg atcccgggga tgttcgaata
   112321 tgttgcgcag atgaaggagg caaggcattc ccaggggggc tgccggatga tccgcaggcc
   112381 ggaacagctg gagacagcgt aatggatcac cggatcccgg tcaatggatg agagtatctc
   112441 cgggaggtcg acatcgaggg cgaagtaata ccggataaac ccggtgtctg caccggaaaa
   112501 ggaaagccgg tctcccttct ggacgattcg aatcactttt tgaccaacaa tccccctcca
   112561 tgccgtctcc tccctctccc agccaaacac ctgcccgcac gagagggaga gatcgaggtc
   112621 gaagggctgg tcctttgcga gaataacgga tggcatagcg gggcaaatcc cagaattcat
   112681 acagtctgct gggatatcag tatgccggag ggggaagggt gggaaaccgc tgacacgaca
   112741 catttcatac cacaggtttt ttttacaacg gcccgctgat aggtacacta tggaactaaa
   112801 tgaagtcctg cgggcattcc tcgagaccgg ggaggattgg gaaaggaaaa acacttccct
   112861 gaacggggtt tctatcatca aactccctgg taccaggaca cgaccccctt cactcgccat
   112921 cgagatcaac ccggtcaacc agaagggcac tcccatgaag aagaaggggg tcatgatcat
   112981 gaacgcgaca gagctctctg cgttccgcga actgttctca aacccaaagg tcgattccct
   113041 cgtccggacc atcgaagagg tcgcacccgg gaaaaaggac cagaagggcg gtgcaggcga
   113101 cgtgcttgta atctgaaagg aaaaggccgg gtctttttaa aaccacaact cctcaatcct
   113161 ttcttcattg ccaatttctg cgatccccct catgttcccg tcctgattgg atgggttcac
   113221 gttgggaagg ataaggatat atcgcaagcg gaagaaaaag tagaactgga aggcagtaat
   113281 cattatgagg tcgatctcac tgcggttcca tgcacccggc gatatttttg ccccgcttgt
   113341 aatcctctgc atactgactc ttgccctggc tctctctgcc ggctgcacgg atgagcgcgg
   113401 gcccagggga cccgttactg aaccacccgc gctcctcatg gattattcgc gtacaggtgg
   113461 tatagcagga ttttctgacc ggatggtgat atacagtgac gggggggttg tctaccagac
   113521 ccgccagaaa tcaggtgcat tcaccctcga ccaggaaaac atggagaggt tgaagagact
   113581 catccgcgac gtcgaggcct ccggtctgaa cgggacatac ccggcaccat cgcagggcgc
   113641 agactatttc tcctatgcgc tggtctttgg aaaccggact atcaagacag agacaaccgg
   113701 cgtcccggag gccctctcac cacttatctc gtttctcgat gagatcctcg ccgcaaaccg
   113761 ggatacttaa tgatagtacc tttttcacga accgggaagg ataatgtatc tcaaaggggt
   113821 ctttaaaacc cattaaaaaa ttctggattc gtgacgcttt gcaatggatc cagagaatgc
   113881 gggcagggaa aaggcaggaa acaatgtatt caggaaaatt cctgaaaaaa tcaattatcc
   113941 cttgaattcc tgccaaaaaa gaaaaatgcc tttccctatt cggagtaaag gcatgactgc
   114001 acgtcctgcc cgagcctccc gattgcatcg gccctgcacc gctggcagtg ccgcatctgg
   114061 cggacatatt tggcacagtc gtcctgcatc tttcgtttca tctccggtgt gggaggggca
   114121 atatgcgaaa aacggtactg ggcaatcagc gggatgacgt tgaaagtgta aacccccatc
   114181 tctccgactt tttttgctat ttcagggata tggtcctcgt taattcctgg tatatagacc
   114241 gtgttgactt tcacaatcat cttgcgttcc acggccatcc gaatcccctc gagctggttt
   114301 ttgaggagga tttccgctcc ctccctcccc tcgtaccgtt ttcctttgta atcaacgaac
   114361 tggtagattt ttgccccgat atcggggtcg atagcattga gtgtgacagt gatatttcca
   114421 acgtcgtatt tatggagaag gtcgatcttg tccgggagga ggagcccgtt cgtactgatg
   114481 cacttgatga cgttgggaaa ctcctcgtgc aggagtcgga gggtctcgaa ggtctcctcg
   114541 tttgcgaggg gctctcccgg tccggcaata ccgatgacct tgatgtatgg atacttttcg
   114601 atagctttcc tgaccatctc gacggcttca cggggggaaa ggaccttggt agtcacaccg
   114661 gggcggctct cgttgacaca gtcgaagtcc ctgatacaat aattgcactg gatgttgcac
   114721 cggggagcaa caggtaaatg gcagcgcccg aaagcatggc aggctttttc cgaaaagcat
   114781 ggatgttccc gtatcttgcg aagctgttca gggtcccatt ggaccttctt gccaccgaca
   114841 tcggctacct tgtactcgtt ttccgtcatg aatttcgccc cgaagcggga ttgttatcct
   114901 gctgctggaa aatgtagaag ctgtgatatt aaatagaatt ctattcaggc acgggatatg
   114961 ggtttttttg gaatcaaatc cctccattgc gggaggggtt gcaaaagagt tccggagggg
   115021 ttattgccgg gcagcaacac accttttttc catgatggca tctggacaaa aacaaaattc
   115081 gagaggtaag gaacggtttt tggttccggc gctgagcatt gctgtcatcg catgcattat
   115141 tgtcacaggg tgcacgacaa tccagcctgg aacctcgcag ggagctgcaa taggggacac
   115201 ggtcagggtc acgtaccgga tggcattccc cggaggagaa cccttcgaga gcaacgagaa
   115261 cagcacgccc ctcgaatttg ttctcggttc cggtgtcatg atcaggggct ttgatcaggc
   115321 aatcgtggga atgaagccgg gagagacgaa aaccgtcatc atcccgccgg aacttgggta
   115381 tgggcagcgt gacgaaaaaa tggtggggac agtcagcacc cccctcctca agaagatcct
   115441 ggatgacctg gaaaagaatg gcacttttac gcagattgaa tttccaggcc ttaacggggt
   115501 catgtacagg tataaactga atgataacag ggtcgtttac tatacattca cgaatatatc
   115561 tccggagacg acgactgtcg accagaacca tcccctcgct ggccacgagc tcgaagcaac
   115621 catcacgctc cttgagataa cgaggaaggc atgaaagcgt gtgggaccgg gcgcaaaggt
   115681 ttcaaattta ttcttttttt gggtttttaa ggaaagaaaa cgagtatcaa ttgtttgagg
   115741 gaggcaccgg gtttgtgcct cccgatgcga tccgatactt tttttatcac aatgtgatat
   115801 ctcattctgg tgtaccggga agcgtcgcca cttccaaagc ctggagtact gcctatattg
   115861 atgccacctt gattgtatag tgctttttca ggcaggcgtc gcccgctgaa cggtgcacca
   115921 aaaaatccat tttacctcct tgtatataaa tgccatggtc gaaagtggat ttttcaggtc
   115981 tattttggca tgcgtcagac attctgaaac ggaattttca atcggaacaa taataacaat
   116041 ctgtctctga aaaattgata taatttctca aaatgagaaa atactaaaaa ataatcgata
   116101 ttaaagagtc cttcccggaa actgcccgat accatcccta caagcaggga tgcgggctgt
   116161 ctgacagaga tcgcataagg gaaggtaaaa accatgcctc cggggacggg ggtgccgcag
   116221 gtgcagattt aaataatttt tggcagtccg tccggctttc ccggtgctaa agcggaaatg
   116281 ggcccggccg gattcgaacc ggcgacctcc gccgtgtaag ggcgacgtca tgaccgacta
   116341 gaccacgggc ccggacagcc agaaaaattc aaccgtgaga gtattaaagg cacctataag
   116401 atttcatgga aaaaatatca gtgagaggag tctttttaca tgggggaagg ttccccatca
   116461 cttcctcttt cctgccaaaa acattccatg gatctcctcc ctatacagtt ttttgtttcc
   116521 ggtccccatc gtccaggagg cagtatccag aaaaacgggc tcgttagggg aaaaaaggtc
   116581 acggatttct cctggagaga agaaatgggt gcagattcct gttttccgga tgtatgtgcc
   116641 ctgctccact tctattccct ctccggccct gaaatcggac agggaaaaga cacggacgta
   116701 gatcctgccg tcccgcctga cgacacgggc agcctcgcgt accatccgtt tccggtcatc
   116761 cagcagggca tggccgagaa cgtggataag gaaaactgtg tcaaacgttt catcgggaaa
   116821 tggcatcaat gttgcatcgg cgcagacaac atgcatgtta tccatccggg agacgagagg
   116881 acggcagata gagagtgctg ggcgggaatg atccaaaccg acagagatcg cggagagacc
   116941 ggttccccct gccagagcaa gtgcacgaaa tgccctgcag tccccgcacc cgacgtcaag
   117001 gaaacgttca ccaggcagaa tttcgggata atcctgtgtg attcttccga agatgcgccc
   117061 ccttcgcgtg tattccctgt cccaggcatg gcggaagcgg ttttccat
//
LOCUS       DAOOJU010000003        88387 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_283_length_88387_cov_17.013845, whole genome shotgun sequence.
ACCESSION   DAOOJU010000003 DAOOJU010000000
VERSION     DAOOJU010000003.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 88387)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 88387)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88387
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_283_length_88387_cov_17.013845"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..316)
                     /locus_tag="PK679_01490"
     rRNA            complement(<1..316)
                     /locus_tag="PK679_01490"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01959"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01959"
     gene            complement(812..1552)
                     /locus_tag="PK679_01495"
     CDS             complement(812..1552)
                     /locus_tag="PK679_01495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ScpA family protein"
                     /protein_id="HPC54664.1"
                     /translation="MPEEPVEILVQMAERGEIDPWNIDIVEVTDRFLQELERRKELDL
                     RISGRTLFYAALLLRMKSEYLEEAGLPGEEDYDEGGADEEDSFRFDEDIEAGENVLGP
                     IERLEREIKRRLDRKQLRKRPITLFELILELKAAEREQRRRQRFIHGFDPTLIEVDDV
                     VGIAHDEGYRDAAHDILDQYGERIEREGVMTLEEIAALMGKKIIDVYIPLLYLMFEEK
                     ILLWQEEFFGQVFVGIRGAQDSVVPEQS"
     gene            complement(1545..4985)
                     /gene="smc"
                     /locus_tag="PK679_01500"
     CDS             complement(1545..4985)
                     /gene="smc"
                     /locus_tag="PK679_01500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HPC54665.1"
                     /translation="MHITELEIDNFKSFIKKTKIPFYEGFSVISGPNGSGKSNIIDAI
                     LFVLALSTSRTLRAEKLTDLINLNSGRNSAEVTLTFSDGTKIRRRIKRSPTGYYSYIY
                     LNGRLSKQSEVNDLLARHGIKPHGYNVVMQGDITRIIEMSDFERRKIIDEIAGVAEFD
                     QKKEQALSELEVVRERIEREELLLRELSQRLEELAREREQALLYRQWQETLQRLEGMR
                     VAATLHARERDLAALSRVIEDERIALERIHSDRSLEENEIAYLKKDLEEIDSQINQKS
                     GAEYLRLIADLEEAKATIRLAEQSIARAGKEKEAGLEGLSRAYIDQKRAETRVAECTQ
                     AIREMTIDRTNLAMEVATLTAQVGKIEEQIKSQSRDAEGARDELFSLMQEVEAKKGER
                     STLLHQKDMLLERSRMRTSEKERLEERLGALTLEYQEKDEAVERNLQEKGRLEKEKAG
                     LDRILSDRESSVFAKRTSLERLREEFREYEQEVIRLEAQQQVRGEAGSRALEPILRME
                     GVYGTIAQLGRASPEYSTALNVAAGSKLHYVVVKDDTVAARAIEFLKEQKLGRVTFLP
                     LTKLKPPDLPPVKEPGMIGYAVDMLEFPPQYAAAFRVVFGGTVVMQSLAQARKLIGKY
                     RMVTTEGELLEKSGAMTGGSFRKPPRGFGAAVEDEVARLRSRMENLSEEIAQVEEEIK
                     SGTREIEELRTKRGEIDAEISRLAIVTEEITRREEVFQREKTQIGEAISSLEEEMRSG
                     IAELAALEAALDRITDTVAQTQKKIDQVKKKLEDTQIPALSEQLEKKKRERDEAERRL
                     RNKESDINDMARERQHFSSRLEELKAEIERISARNADIDREIALSTEQIEANKVKIAG
                     IEERQKQFSSELQELRDRHDRVSLAIKESGEKILALDATAERHRVQLEALNERFVALS
                     REVEDLRSQAGDMDTDMTLEEIEDGIAKAGLEIRKIGAVNMLAIEEYERVEKRITERN
                     EKKEVLSRERENLLERIERFEKMKFEAFMTAFRAIDANFREIFARLTSGSGHLVLENE
                     EDPFSGGLSFAVQPRDKPVHLLSALSGGEKSLTTLAFIFSIQQYIPAPFYAFDEVDMS
                     LDGSNVERIATMIRELAQTSQFIIVSLRKPMIEGADRILGVTLLPDKSSFVTGIKSHA
                     "
     gene            complement(5000..5494)
                     /locus_tag="PK679_01505"
     CDS             complement(5000..5494)
                     /locus_tag="PK679_01505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54666.1"
                     /translation="MEIIKDKDLGQSPLDERVAALEKKVREIDALVKGLTEELLDLKS
                     VAMKLSKVSEERARAEMRMTKPAPGGQGQGPIIMQTKTRPQTQMQRPAQSTAQPAPQS
                     EPEKMDMIMQPDGTLKPEKRKNSDYIIASAGFSKKKQNVQGSGKKSDLIVAEDEEGEP
                     AEKR"
     gene            5813..7051
                     /gene="glyA"
                     /locus_tag="PK679_01510"
     CDS             5813..7051
                     /gene="glyA"
                     /locus_tag="PK679_01510"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HPC54667.1"
                     /translation="MSYLASTDPEIADIIRKEMERQRDGLELIASENVVSRAVLEAMG
                     SIMTNKYAEGYPGKRYYGGCEFHDMAENLARDRLRKLFGAEHANVQPHSGTQANMAVY
                     FATMKLGDLMLSMKLSQGGHLSHGSPVSFTGQFYRVAQYGVDPKTEVLDYGVVEEIAR
                     KERPSMIVCGASAYPRTIDFRAFQEIADSVDAFCMADIAHIAGLVATGLHPTSVGVTD
                     FTTTTTHKTLRGPRGGAIMCGKENAAIIDKAVFPGMQGGPLMHTIAAKAVCFGEALRP
                     SFREYNKQIIRNAKVLAESLMDHDLRLVSGGTDNHLMLIDLTDRGITGLEAEQALGRA
                     HITVNKNTIPNEQRSPFITSGLRVGTPAVTSRGMKEGEMRQIGEWIGTILKDIHNEQA
                     IRTIGEEVKSMAAKFPLYPD"
     gene            7053..7895
                     /locus_tag="PK679_01515"
     CDS             7053..7895
                     /locus_tag="PK679_01515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HPC54668.1"
                     /translation="MILDGKRISEERLAKLKEEIRNSGLFPSLATVIVGDDPASRMYV
                     RMKHRACEAAGIRSVGVELPSSASTKDVLGSIENLNSDPGVNGILVQLPLPSHIDTPR
                     IVESVDPRKDVDGFHPYNMGCLFLGTPVFSPCTPAGIMTLLSAYGVEPGGMHAVVLGR
                     SIEVGRPMAALLLNAHATVTICHSRTRDLPSITQKADILVVAVGKPKFIGPQMVREGA
                     IVVDVGTNRVEGILCGDVDFERVRDVAGAITPVPGGVGPMTIATLMENTFLAARIQAC
                     TDAR"
     gene            7877..8689
                     /gene="folP"
                     /locus_tag="PK679_01520"
     CDS             7877..8689
                     /gene="folP"
                     /locus_tag="PK679_01520"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HPC54669.1"
                     /translation="MYRCTVKGLSIGGGAPVRIMGVINCSPESFYSGSYTPAGNVHSR
                     ACTFVEQGADIIDIGARSTAPGAPPLDRQKEIARMKMALTSLEGSGIRISVDTMDREV
                     LEVCLGYDIALVNDISGLLDPLYASRVSESGLPALLMASIKAPGDPTSLDEVHRAIAM
                     VETRAHAAGLAEFILDPGVGLWTPERSPALDWEICCNFEEFTMYNRPLLAAISRKTFL
                     GVIGDRPPEGRLPASLAMTALLVTRGADIVRTHDVAETHDAIRVAERFRRGS"
     gene            8686..9459
                     /gene="cofE"
                     /locus_tag="PK679_01525"
     CDS             8686..9459
                     /gene="cofE"
                     /locus_tag="PK679_01525"
                     /EC_number="6.3.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043773 - coenzyme F420-0 gamma-glutamyl
                     ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HPC54670.1"
                     /translation="MTVSYTVYGIRTPLITRGADLAGILIDAVTGTGAEEFRNGDVLV
                     VAETAVSTAEGSVIPLEGIEPDEESIRLSRQYSLDPRLVQCIREESDEIVGGIPGFLL
                     CMKHGTLLPNAGIDESNAPPGCVSPLPRDPDGSAARLMHEIRRRTGARVGVIIADSRT
                     HPMRVGCSGVAIGCAGITPVIDARGRRDLFGKELHVTRQALADNIASAAEIVMGEADE
                     STPCALIRGLDIPVTDTCGIETIDASECLFMGLLREKDR"
     gene            complement(9692..10333)
                     /gene="cofC"
                     /locus_tag="PK679_01530"
     CDS             complement(9692..10333)
                     /gene="cofC"
                     /locus_tag="PK679_01530"
                     /EC_number="2.7.7.68"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043814 - phospholactate
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-phospho-L-lactate guanylyltransferase"
                     /protein_id="HPC54671.1"
                     /translation="MGVPAIIPFKPGNPKTRLSCVLSLEEREAFARAMLCDVVDAVCR
                     AGCSPRVVSTALFAFPRCPVEVVPHGLNETLNEILSVTDGPVLIIMADLPLADAASIG
                     RVVTSSRDIAVVPGRGGGTNAIYLTRGNSFRVDYYGASFLKHRRIAEERGLSCEVVDT
                     FRLHTDVDEKEDLVELLIHGEGMSRQFLVDHGFELSVEKGRVGVTRRSPARQV"
     gene            10471..11469
                     /gene="cofG"
                     /locus_tag="PK679_01535"
     CDS             10471..11469
                     /gene="cofG"
                     /locus_tag="PK679_01535"
                     /EC_number="4.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-didemethyl-8-hydroxy-5-deazariboflavin
                     synthase CofG"
                     /protein_id="HPC54672.1"
                     /translation="MVVRIITFSRNIFLPLTTVCHNRCGYCSFRTPVREGCVLPPGTI
                     LETVRQGAILGCTEALFTFGERPGLEPGFNTHLARYGYRDILDYCFHMAEKTIELGLL
                     PHTNAGVLTYEEMKRLAEVNASMGLMLETTARIKAHENSPGKDPAVRIEMIENAGRLR
                     IPFTTGILLGIGETVRDREESLTVIRDIHRRYGHIQEVIIQNFCPKEGTPMARHAPVD
                     SGEMCGAIRMAREILPPDIAIQAPPNLADVASLVPCGIDDLGGISPLTVDYVNPEHQW
                     PQIEELQRQLGNCRLVERLCIYPRFIEKGWYSPRLKPLINRLHQQVQERSKIREEG"
     gene            11456..12184
                     /locus_tag="PK679_01540"
     CDS             11456..12184
                     /locus_tag="PK679_01540"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HPC54673.1"
                     /translation="MKKGEVLYKGKAKSLYRTGDPGVLLVEFRDDITAFDGQKKDVLS
                     SKGRLNAQVSAFLFRLLERNGIATHFIDMPDESHMLVKALDMIPLEVIVRNIAAGSLV
                     RQYPFREGTVLEPPVIVIDYKDDSRHDPMLNDDLIIALGILTPDDLAMIKEMALRVNS
                     VLREFFASLGITLVDFKIEFGRTPDGKILLGDEISMDSMRLWDMSTGKSLDKDVYRFS
                     KGDVMEAYNRVAERVCAEDKEVCK"
     gene            12181..12429
                     /gene="purS"
                     /locus_tag="PK679_01545"
     CDS             12181..12429
                     /gene="purS"
                     /locus_tag="PK679_01545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HPC54674.1"
                     /translation="MTDFLVRITISLKEGVLDPEASLIQRALENLGFPTGELKTSRQF
                     LVRFHAENADDARKRAEAMCERLLANPVIHRYEIEVMK"
     gene            12426..13124
                     /gene="purQ"
                     /locus_tag="PK679_01550"
     CDS             12426..13124
                     /gene="purQ"
                     /locus_tag="PK679_01550"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase I"
                     /protein_id="HPC54675.1"
                     /translation="MRFAVVQFGGSNCDRDVAYVLNDVCGIDTDLVWYKEGLSRGYDA
                     VILPGGFSYGDYLRAGAIAARTRIMDDVRRIAGRNGLVLGICNGAQILAESGLVPGVF
                     TINAYPKFICRPAYLRVENPKNPFTLLFAGGEVIRIPIAHREGRYIPPSAGRTGTLKE
                     ECVAFRFCDPAGNITHESNPNGSFENITGVLSSGGNVLAMMPHPERASEDILGSSDGK
                     RIFLSMARFIEENS"
     gene            13121..13447
                     /locus_tag="PK679_01555"
     CDS             13121..13447
                     /locus_tag="PK679_01555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016730 - oxidoreductase activity, acting
                     on iron-sulfur proteins as donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-thioredoxin reductase catalytic
                     domain-containing protein"
                     /protein_id="HPC54676.1"
                     /translation="MNEEGLKNVLSAEDEREILAWAREYARVHHWTLNPDEKRLMVVI
                     RGLARNRKKYGEKYCPCRLRSGDPEKDRDIICPCVFHGDEIKERGSCHCQLYFDTPDT
                     GKTNTP"
     gene            complement(13452..15107)
                     /locus_tag="PK679_01560"
     CDS             complement(13452..15107)
                     /locus_tag="PK679_01560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HPC54677.1"
                     /translation="MVLKFRRYWQIADVLFKYGFGIIIQRLFPGVHRFRFCRTCPVES
                     AANEYQRMRMAIEELGPTFIKFGQIMSTRQDILPPPLIQELKKLQDQTAPLPFEEIRA
                     VIRDELPGYEDFFDGIEEEPLGSASIAQVHRARLKDGTPVVLKVQRPGIESIIETDIL
                     ILESFARRAERAFPEWKVYNPRGLVKDFANQIRKELDFIRDGTNADMLRNNMKSLRGV
                     KVPKIYWEFSRRRLLVMEYIDGVRVDNVPAILDFGLNPKRIAQNGFIAYMTQIFGDGF
                     FHGDPHPGNLLVTGDGELVFLDFGIVGVIRPERRFWFVQLINGMVARDAGLMVKALEG
                     LSVRIPEQSREDLRDEIYSALLEAEGTTIGQFNFSGMTNAFTTILRDYRIRVPVNLML
                     MLKVIVMVLDVGVTLDPDFRFREEAEKFMAQYSRRESLIEQIATRARGSTIETLDGLL
                     DMPRNVNQMLKQLSTGTIRIDIVDTDIRRLQLSLDRTSNKVLIGLIVSGMVIGSSFIL
                     RESQIQLPQLVYYMAILSYLVAIVIGFYAIYRVLAPGGYEDEK"
     gene            complement(15151..16854)
                     /locus_tag="PK679_01565"
     CDS             complement(15151..16854)
                     /locus_tag="PK679_01565"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HPC54678.1"
                     /translation="MEGPAGEDPLKKALFLFALQNAVRYKSVPRPGTVIGMVMGKHPE
                     FRERARDAAVLVKEAISEVSSLSHARREELLQTLDPALAEDLERPRDHLRGLPALEKA
                     EGGVVMRFAPNPSGPLHLGHARAALLNDAYVRRYGGKYILRIEDTDPKRVDPAAYTMV
                     REDAEWLGLAISDIVYQSDRLDIYYEYAKKLIERGGAYVCTCDSERFRELKMAKKPCP
                     CRGMALEESLDAFSRMLEGGYGEGEATLRVRTDLSHPDPAMRDFPAIRILKSPPHPRK
                     EACVYPLMNFSVAVDDHLLGITHVIRGKDHIANTRRQKYIFDYFGWEPPVYRHYGRMG
                     IEGVVLSTSQMRAGITSGEYSGWDDIRLGTLRAIARRGISPQAVREAVIEIGIGETDI
                     SFSWENLYAHNRAVVDPVANRYFFVPDPVEVTIEGAPSQTAHALLHPANPEKGTRELH
                     FTGKALVPRDELQGEGGMVRLKDLFNVEVVTGGESPVCRYAGESLSEARARKAPIIQW
                     LPPDECVPATLLTPGGTIKGVCERLVAGEAGAVVQFERIGFARIDAVTGEGITAYFAH
                     R"
     gene            complement(16859..17821)
                     /locus_tag="PK679_01570"
     CDS             complement(16859..17821)
                     /locus_tag="PK679_01570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HPC54679.1"
                     /translation="MELKQYLEQTANQVDALIYRYFGSACDDLGRASAHLLLAGGKRL
                     RPALLLLAADAVNRGSSSDVMPAALALELTHSFTLIHDDIMDGDTVRRGVPTVHTRWD
                     EPTAILAGDVLFATAFEFICLADVPDNAKVRATSLLARTCVEICEGQHLDMSFEKRDD
                     VSEGEYFKMVEKKTGALYAAAAGIGSILASGNPSFTEALYHFGQGIGMAFQIQDDLID
                     LLAPPEVSGKDQGSDIREGKKTLVYLKAREKGLDLAQYRGDISPDQIRGIVAKLEELG
                     VIAEVRQTAEDLVRTGIQRISILPDSEEKDLLVQMGEHFIRRSY"
     gene            complement(17848..19185)
                     /locus_tag="PK679_01575"
     CDS             complement(17848..19185)
                     /locus_tag="PK679_01575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase J family beta-CASP ribonuclease"
                     /protein_id="HPC54680.1"
                     /translation="MDIEVIAVGGYDEVGRNMTAVRCGKEIVIFDMGLRLDQVMIHEE
                     AEVENMHSLDLIQMKAIPDDTMMNSVEGTVKAIICSHGHLDHIGAIPKLAHRYNAPII
                     GTPYTIELIRQQIAGEQKFGVNNKLFALKTGQKYTLSQNLALEFIRMQHSIIDTATVV
                     LHTPKGAIVYACDYKLDRTPVIGEPPDFARLRQIGKEGVLGLIVECTYIDNRGRAPSE
                     RIARDIVRDTITSYEDDKSAIIVSTFSSHIARVKTIAECAHEIGRKPVLLGRSMEKYA
                     STAEQMKLVAFPQTMSMFGNRRTVDRTLRRMMKAGKEKFLPIITGHQGEPGSILTRIA
                     LGDTPYKIEKGDKVIFSAKIIPNPMNIGQRYMVEARLNMSGARIFPDLHVSGHAYRED
                     HYEFVHMLNPQHVIPAHGNIRMSSGYAEFSESLGYTLHKDVHILSNGHRVKLD"
     gene            complement(19190..20266)
                     /gene="fni"
                     /locus_tag="PK679_01580"
     CDS             complement(19190..20266)
                     /gene="fni"
                     /locus_tag="PK679_01580"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HPC54681.1"
                     /translation="MDKKRFTSGRKLDHLRICAEEEIERGFSGFSDIRLVHSALPECD
                     LSRIDLSTRFLGRKLSSPLFIAAMTGGHPDTTEVNVRLARAAERYGIGMCVGSQRAAL
                     EDPALEESFRVVRREAPGAFLVANLGIVQLREHGPDWAGRAIDMIGADAIAIHLNFLQ
                     EAIQPEGDHDATGCTEALARFCRESPVPVIVKETGSGISRETAEACWGAGVRAIDTGG
                     WGGTSWAAIESFRAGKSRGKKNADLFALGTLFQEWGIPTAVSLVEVVGTGGPVIATGG
                     IRTGLDMAKALALGADLCGLALPLLRPAMESEEALFSRIEELNRELQTAMFLCGAKKT
                     RDMKRTRVYITGKTREMIGKIKGG"
     gene            complement(20259..21032)
                     /locus_tag="PK679_01585"
     CDS             complement(20259..21032)
                     /locus_tag="PK679_01585"
                     /EC_number="2.7.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl phosphate kinase"
                     /protein_id="HPC54682.1"
                     /translation="MPERILLKLGGSILTDKGREGVADLGRIRSIAGEIARRDGSDIC
                     IVHGAGSFGHPEAHRYGLAGGERGADLAEGIARTHAAVCSLNAILVSALFESGIEAVG
                     IHPLGSAIAHDGRLVALGERPLLALMEAGVTPVLHGDVVMDEARGVSIVSGDQIVRFL
                     AERIPFTRVGLATDVPGVLDSGGTVISRIGPESGPMVSAGSSGHTDVTGGMAGKVQEL
                     LGLAKCGVSSDIFHVSRLGDFLDGRPHGGTRITGSNTNG"
     gene            complement(21025..21894)
                     /gene="mvk"
                     /locus_tag="PK679_01590"
     CDS             complement(21025..21894)
                     /gene="mvk"
                     /locus_tag="PK679_01590"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HPC54683.1"
                     /translation="MATWSAPGKVFLFGEHAVVYGKPGVAMAIRPRVFVTVRKSKTAH
                     HARSPYIDSCFDEMGVRGSVYVNSQLPSSSGLGSSAAVTVATLAAINDEFGKNLTMEE
                     IAAIAYRIEKKVQKGRASPTDTSVSTFGGIVLITGTQRRRLPPQNLPLVIGNSLVSHS
                     TAKMVEKVAEFRKKNPDICDPVLDAIGAVSLCAIRNLNNNHELGRLMDTNHALLEALG
                     AGHPVLSRLILAARAAGAYGAKLTGAGGGGCMIAICPKHLKSRVAGAIEACDARALIT
                     TLDTEGVRKEKDA"
     gene            complement(21896..22687)
                     /gene="amrB"
                     /locus_tag="PK679_01595"
     CDS             complement(21896..22687)
                     /gene="amrB"
                     /locus_tag="PK679_01595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system protein B"
                     /protein_id="HPC54684.1"
                     /translation="MMTRKCAVAGMFYPRDPDHLEQLLEKFFRNKDSGLDARGIVSPH
                     AGYPYSGEVSAVAYGAIPSTFSGTFIVIGPSHRGFCTCISLVPWETPLGLVDNDSQLG
                     SLLGVEVDEVSHQYQENSLEVQIPFIKYRFPRARIVPVLMGDQDLQSAADLAEKIVAG
                     IRKSGRSDVRIVASSDFSHYVPKATAIENDLYAIEPLLTLDVEGFYRRLRERRVSACG
                     YGPIATMCLACRSLGAREGKLLRYATSGDVTGDPEVVGYAAIAVM"
     gene            complement(22717..23325)
                     /gene="rpsB"
                     /locus_tag="PK679_01600"
     CDS             complement(22717..23325)
                     /gene="rpsB"
                     /locus_tag="PK679_01600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HPC54685.1"
                     /translation="MPETEMEIELKEPLVPVEEYLAAGIHIGTQQKSKDMMRFIYRVR
                     GDGLYILDIRETDERIKTAAKFLNQFDPGHILVVTSRQYGQYPASKFAETIGGMAVTG
                     RFIPGMLTNQNLDRYIEPAVLVVTDPIGDAQAIREAVQSGIPIVALCDTNNMTSLVDL
                     VIPTNNKGRKALSMIYYLLTKEMLRLRGISTSLTPEDFETEI"
     gene            complement(23440..23610)
                     /locus_tag="PK679_01605"
     CDS             complement(23440..23610)
                     /locus_tag="PK679_01605"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit K"
                     /protein_id="HPC54686.1"
                     /translation="MKETYTRYERARIIGARALQISMGAPLLIKTDKIDPLEIALEEF
                     QHNVIPITVKRK"
     gene            complement(23643..23717)
                     /locus_tag="PK679_01610"
     tRNA            complement(23643..23717)
                     /locus_tag="PK679_01610"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23679..23681),aa:Pro,seq:cgg)
     gene            complement(23718..23906)
                     /locus_tag="PK679_01615"
     CDS             complement(23718..23906)
                     /locus_tag="PK679_01615"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit N"
                     /protein_id="HPC54687.1"
                     /translation="MIPVRCFTCGKVISPAYEEFKRRKEAGEDPKKILDDLGMVRYCC
                     RRMLLAHKEIIDDLNPYQ"
     gene            complement(23939..24340)
                     /locus_tag="PK679_01620"
     CDS             complement(23939..24340)
                     /locus_tag="PK679_01620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HPC54688.1"
                     /translation="MGKVINTSGKRKTAIARATVRAGKGIIRINSVPLDLYPNEMVRL
                     KVSEPVLLAPAALEGVDVSIDVRGGGIMGQAEAIRTALARGLLKWHNDPKIKDIFLSY
                     DRTLLVNDSRQKEPKKPHGRGARKKFQKSYR"
     gene            complement(24354..24776)
                     /locus_tag="PK679_01625"
     CDS             complement(24354..24776)
                     /locus_tag="PK679_01625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HPC54689.1"
                     /translation="MTTIINGDGLLLGRMASIVAKRALNGESIAIVNAEKAIISGSRA
                     RVLSQYGQKRSRGSREGGPFFPRRPDHIVRRTIRGMLPYKRPAGMEAFKRIRVYVGVP
                     SDLAGSPMETLEEAHMNRLNSPKIVTIGAVSTFLGAKF"
     gene            complement(24782..25150)
                     /locus_tag="PK679_01630"
     CDS             complement(24782..25150)
                     /locus_tag="PK679_01630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18e"
                     /protein_id="HPC54690.1"
                     /translation="MKKRAIKKTNPRLLNLISLLKDASRQNEALVWRDIASRLEAPAR
                     NYAEVNLSKINRYAGNGETIVVPGKVLGSGMLETSVRIAALNFSQSAETKIREANGQC
                     MTIEELIRDNPRGSKIRILR"
     gene            complement(25131..25976)
                     /locus_tag="PK679_01635"
     CDS             complement(25131..25976)
                     /locus_tag="PK679_01635"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit D"
                     /protein_id="HPC54691.1"
                     /translation="MEIEILRMDDSQARFCLSGPSQAFANAFRRAMIGEVPTLAIEDV
                     RIYDNTSALFDEMLAHRLGLIPIKTEPGLYVPQDKCSCGGEGCDRCGVAFTLSVEGPG
                     MVYSRDLIPQDPRAVPAVDTIPIVKLGKDQKVVLEARAVLNCGRVHAKWQPTTACGFK
                     NYPVIDVSNRCDGCGRCVDECPRSILEVRNGRVTVIENRLEECSLCRLCEKACMSTGI
                     GEEPAITITSEKSRFIFVVEGDGSLPVGDIITGALKYLKDQSDELRAQVSELSGVTGD
                     EEESD"
     gene            complement(25976..26371)
                     /locus_tag="PK679_01640"
     CDS             complement(25976..26371)
                     /locus_tag="PK679_01640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HPC54692.1"
                     /translation="MAGEKEKWGIAHIFASFNNTIITITDLSGAETVCKSSGGMVVKQ
                     DRNESSPYAAMQMATNVAQAAMEKGIVGVHVKVRAPGRGKQRSPGPGAQAAIRALARA
                     GMRIGRIEDVTPVPHDSIRPKGGRRGRRV"
     gene            complement(26377..26922)
                     /locus_tag="PK679_01645"
     CDS             complement(26377..26922)
                     /locus_tag="PK679_01645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HPC54693.1"
                     /translation="MGYPGKNHKQYQTPKRPFEKSRIEEENRLMIEYGLRNKREVWKA
                     ASHLRRFRRAARDLLALMSTGKDQTLFEAKKSDLIEHLQRMGLLGPDAGIDDVLSLKV
                     ENQLERRLQTLVYRKGLARSPKQARQMITHGHIAIAGRRVSIPGYRVSRAEESEIGYY
                     RRSPVANPDHAERARIARAGR"
     gene            complement(26939..27391)
                     /locus_tag="PK679_01650"
     CDS             complement(26939..27391)
                     /locus_tag="PK679_01650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HPC54694.1"
                     /translation="MAQEEDIRYFVRISNTDLDGTKPVTTALTGIKGVGRHTALVIAQ
                     MAGVNPRELMGKLSEADVDKLREVVETYEKKVPAWMVNRPKDIYTGEPRHLFGTEVVT
                     TLDEDINLMRKIRSYKGIRHETGQKVRGQRTKSTGRTGATVGVKRKKE"
     gene            complement(27430..27514)
                     /locus_tag="PK679_01655"
     tRNA            complement(27430..27514)
                     /locus_tag="PK679_01655"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(27478..27480),aa:Ser,seq:gct)
     gene            complement(27812..28813)
                     /locus_tag="PK679_01660"
     CDS             complement(27812..28813)
                     /locus_tag="PK679_01660"
                     /EC_number="2.5.1.46"
                     /inference="COORDINATES: protein motif:HMM:NF002006.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyhypusine synthase"
                     /protein_id="HPC54695.1"
                     /translation="MRTTEPVVPSDNVAELLRRMARCGFQGRKLGESVEVWKEMVSDP
                     ECTIFFGLSGAMLPAGMQKVLIELARRHYIDVVVSTGANIFHDVCEHLGVCHYLGHYH
                     VSDSELYEKGIDRIYDIFAYEEDFRWVDRGIANFAEKIAPFRGSSREFLRLFGEWLMK
                     AVPGRESFLSTCVREGIPVFVPALCDSSIGIGALIARRRGVQIDIDQVADTDEVTSLV
                     EEVKRTGVIYVGGGVPKNFIQQTQVIGSIHAKDLGGHDYAIQYTTDSPHFGGLSGCTF
                     EEAISWGKESAHTRHVQVHVDATIALPLVVSALIADDVRRVAHAPARREKILRQGID"
     gene            complement(29122..29898)
                     /locus_tag="PK679_01665"
     CDS             complement(29122..29898)
                     /locus_tag="PK679_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54696.1"
                     /translation="MTEEILVKDIMSRPVTISKSAPITEALDRMLDEGVDPLIVVNHD
                     SVVGTVSRQSVAEKLGTKRNSSISPTSIHVASTVEEDFTTVYPDQDLDVVIPLLQTYK
                     LVVVYDEDHRLVGQVTAGDILRVMRPQGKLEDVLEPACTIDQDERVVHWRRRMIDDNL
                     HRCLVTENGRLIGIVTETDVAVAMRKFREIVEDRHQDHRIRNLLVKDIMTTPVITLGM
                     NATIDEAADLMLSRGISSIPVVNGDRIVGMVTRSSLIRAL"
     gene            complement(29895..30734)
                     /locus_tag="PK679_01670"
     CDS             complement(29895..30734)
                     /locus_tag="PK679_01670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54697.1"
                     /translation="MQAKDIMSSPVYVVGPGENIAHARKIMLKHRISRLPVIEEGNLG
                     GILTKKDIGYRLRQSEPVWRRRPIDNIPVSLLMTRDPITISPETPTRKAAGLMIEHDI
                     SGLPVLNGTEVAGIVTKSDLMRSEAVRNLDMTVADVMEDAITVSRYHSLDHVIDLMKE
                     RNDKVIVVNNDGTLAGIITESNLAFFLYEDEKRDIPIKDVVMLRRGESGGRKQFRYVM
                     EAAAIAEDLMSRPVITIAGSATLKEAVQMMQSHRINSLVVVEDDEIRGILKRDDIIRE
                     VAK"
     gene            complement(30741..31685)
                     /locus_tag="PK679_01675"
     CDS             complement(30741..31685)
                     /locus_tag="PK679_01675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54698.1"
                     /translation="MAHHGDKSYKQGDKLLKMPGKLDRGPVEFKSRIVEQKGEIMAIA
                     TRDVVSVPQTMTILGAVSTMTECGFRRLPVVDAGSKKLRGIVTSGDIINFLGGGDKFN
                     LVQVKHKGNLIAAVNESIRTIMTTNVTTLPDSASLDDAIGIIKEKMTGGIPIVDDSSA
                     LAGIVTERDVMTVLAGERVSSTVEDIMSTSLRVTEPDCPIGWVTREMTRHRFRRLPVV
                     SGDVLYGIVTTTDIVKYLGSRKVFDQMESGDIAEVMALPIRTLVSGKLYTISPEKSAN
                     EAAAEMVKRGVGALPVIEGTRLIGLVTEFDLVRAFSGE"
     gene            complement(31738..32496)
                     /locus_tag="PK679_01680"
     CDS             complement(31738..32496)
                     /locus_tag="PK679_01680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54699.1"
                     /translation="MKKARDFMVEVPHFKHDEKVTKVRSVLRDAFIREAYVHDGKGRL
                     LGYVDITGVLRVPATRSDVTIEGFVKEVTPATPDDSIEKVVKLIRMNGTDSVPVVDEQ
                     ERVIGGVRLPDIFPVIASRHSLDGKVADYMSRDVISCDAEDTVQKIYNLIVESGYSAI
                     PVMKKRRLVGIISRSDLLRDGRWRPAREGPAKTKVENVMTTPVITVSPGDELQQAAGI
                     MVKHDISRLPVLDGDRLAGILDRHDVLKAVPQEA"
     gene            complement(32493..33062)
                     /locus_tag="PK679_01685"
     CDS             complement(32493..33062)
                     /locus_tag="PK679_01685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54700.1"
                     /translation="MSKSSGKIHFNTRVPVREVMRRNPTTIGYEGTVARAAMLMCRDE
                     VGSCIVLGPNNLPIGIVTEEDINCKVVAKDIKPGSVLAHDIMSTPLITINADKSVGDA
                     AHMMIKHRVRRLPVVDDENRVIGIVTVRDILTVSTEINELMADLVEINRLEEVEVGLC
                     SRCGQMSDDLRRIDNNLLCPSCREEELLQ"
     gene            33265..33906
                     /locus_tag="PK679_01690"
     CDS             33265..33906
                     /locus_tag="PK679_01690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Era-like GTP-binding protein"
                     /protein_id="HPC54701.1"
                     /translation="MNILVQTKKRISRFLSAFFRKKRARIGIYGPPNAGKTTLANRIA
                     KDWTGEDVGLVSEIPHETRRAARKADISIMGSNGSNITIDIVDTPGVTTKIDYRDFLE
                     YGMDKETAVSRAREATEGVAEAMHWLREDIDGVIYMLDATEDPFMQVNIMMIGIIESR
                     KLPVIIVANKIDLPDAMPQRIRSAFPQHPVVPVSCTEGKNIEDLYEKMVEYFG"
     gene            33916..34281
                     /locus_tag="PK679_01695"
     CDS             33916..34281
                     /locus_tag="PK679_01695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2073 domain-containing protein"
                     /protein_id="HPC54702.1"
                     /translation="MMQGVQIDLISSEKLEKLTSMEKIHLILDHVRQGTIIILEKGLS
                     PDEQSTLIEMTMREILPDGFNGIEIETYPSREQSPGFLQKLLGKATPESRLTVIGPAN
                     QLRLIRKEKDILSAWVSTR"
     gene            34286..34678
                     /locus_tag="PK679_01700"
     CDS             34286..34678
                     /locus_tag="PK679_01700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-ribbon containing protein"
                     /protein_id="HPC54703.1"
                     /translation="MPHKCVRCGKEYRTNECEILKGCRECGGKKFVFIPQVEREPEKE
                     PVTPVTPAASPETQDKEKEPDTAPDVPLLGTDRLESIRIVAPGTYELNIEKLATSDER
                     VVGIGKGEGSYLVDLLSMVRPRRKKAKK"
     gene            complement(34693..34998)
                     /gene="yciH"
                     /locus_tag="PK679_01705"
     CDS             complement(34693..34998)
                     /gene="yciH"
                     /locus_tag="PK679_01705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HPC54704.1"
                     /translation="MNGGICPTCGLPKELCICEEVAKEQQRISVKVDRRRYGKEVTVI
                     EGLNPTDIDLEDLSKYMKGRLACGGTVKGTSIELQGNHKERVKELLVSKGYSVDNIN"
     gene            complement(35096..36748)
                     /locus_tag="PK679_01710"
     CDS             complement(35096..36748)
                     /locus_tag="PK679_01710"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HPC54705.1"
                     /translation="MELCKPAEALLASRYLLPGETPEDLFRRVAKAVGTSKADLFAGI
                     MSELKFLPNSPTLMNAGTQCGQLSACFVLPVEDSIEQIFSVLRYMALIHKSGGGTGFS
                     FSRVRPKGDMVGGSAGVASGPISFIRVFDEATNALRQGGKRRGANMGVLSSHHPDILE
                     FIHSKETGGLQNFNLSVGFDAEFFSCLGQGHAYPLVNPRDGEVWREIEPRDLFDALSM
                     AAWGCGDPGVLFLDRINEKNPVPALGEIEATNPCGEQPLLPWESCNLGSLNLSRFLKK
                     GDIDWDSLRECVWLAVEFLDAVIDVNRFPLPIIRECTLQTRKIGLGVMGFADMLIRLE
                     VPYQSKEALTLGENLMRFIQEESHAASRTLGEEKGSFPAIDRSIYSGSMRNATVTTIA
                     PTGSLHIIACTSSGIEPLFACASERVIDGKRFAIVHPELRKHFLGLPNGKELLLEAER
                     KGSVQDLPVSRDIRELFRNAGEIDPRFHVRIQATFQKYVDNAVSKTVNLPTEASPGDI
                     SGIFLYARELGCKGITVYRYRSRKDQVISRGCDACRVDTLVA"
     gene            36802..38238
                     /locus_tag="PK679_01715"
     CDS             36802..38238
                     /locus_tag="PK679_01715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HPC54706.1"
                     /translation="MSLMVLGTSSHAGKSTVVAAICRVLSNRNISVAPFKSQNMSLNS
                     YVTRDGSEIGIAQAIQAKAARLEPVAEMNPILLKPKGDAVSQVILLGKPYKDVPAQEY
                     YRETDFLLSKALLAARALEEKFGHIVVEGAGGAAEVNLYSRDIANILIARALRYPIIL
                     VADIERGGVFAQVYGTVSLLPPDIAPLVCGIIINKFRGDPGIFASGKEIIEELTGVPV
                     IGILPHMEIGLPSEDSLSIGDKKSRSFPVRVGIIRLPHISNFTDFEALEKCVAVDYVP
                     LGSSLSGYDCIIIPGTKNTVSDLMELWQSGTAEEIRKTAMEGKPVIGICGGFQILGRE
                     IIDSGVESRAGVFPGLGLLGVVTRFDRYMKKTEQVTLRARPVGPILGTMGTVSGYEIH
                     MGITSNEGEEEAFEGEGAVSSSGLVFGTYLHGLFSNPPAVDALCRYLYEKKGLSYRDW
                     KDTSDPYDDLADAFMQHVRMDIIYSFFQ"
     gene            38347..38685
                     /locus_tag="PK679_01720"
     CDS             38347..38685
                     /locus_tag="PK679_01720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HPC54707.1"
                     /translation="MPIRLSITIDSETIDQVDKFAKEQGFDRNRAILECIRAGIQKVN
                     AGEQVNISQTTRLEDYKEIRAILNNIDATLKNLVEEIRVMHHTIEAEWLKENRTVPYQ
                     SRKWYEFWKT"
     gene            complement(38713..38979)
                     /locus_tag="PK679_01725"
     CDS             complement(38713..38979)
                     /locus_tag="PK679_01725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54708.1"
                     /translation="MSGEKYRVLEVRAGKVDCLPGRKEPVEHCRFCVHSRYFRIGGQY
                     KKSPALVYCLRHRDAEEVDLSLVEAVKCGDLQGEGYRSMMNILG"
     gene            complement(39083..40354)
                     /locus_tag="PK679_01730"
     CDS             complement(39083..40354)
                     /locus_tag="PK679_01730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54709.1"
                     /translation="MLKKVRDLFASRQTVPPREISLEEIPVIIGEEEHSWREELQKRM
                     DQPREKFTEVCSALLVRATTLAGSERDSVYHPKLEKITRNSLPQFEKAITTSLARQAP
                     PDPSAFYQVATETLKGCVKALAGPGRYLGTAFPDQMKEVRVLIDELGHQVNEMTPLIA
                     EDKRRNRSFSRARESFISIREKQAALAEARERLSILEAREKDLGIRQEGLAREKEDCD
                     RRAGMDGALQDAVRHKEEFTGRVAGIGREIHGTTSTLVHVFAKAEKILQKRGGGEKEI
                     KRVIDIISQEGENIDEGSVEKVRNVLPLVTSMISSGDIQLKNQEEINLFSNPDRICPA
                     LVSLVYRRKEAEGYLRKKEEFIHSHPEVKRAAQVEKALRDIENDREKIRTEIVTIREG
                     IRVMEKEIPERIHELEAALRELFTGGIRLKI"
     gene            complement(40364..40888)
                     /locus_tag="PK679_01735"
     CDS             complement(40364..40888)
                     /locus_tag="PK679_01735"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000309 - nicotinamide-nucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide adenylyltransferase"
                     /protein_id="HPC54710.1"
                     /translation="MIRGLYIGRFQPYHNGHQHILEEIARRVDEIIIGIGSAQLSHEP
                     SNPFTAGERLLMITRALGTIGNPVYVIPIEDLHRNALWVAHVRSMAPRFDIVFSSNPL
                     VVRLFGEEGIAVESPSMYERASHSGTEIRRRIIAGEEWESLVPPAVADVIREIDGVAR
                     IRQIARDDGDGRCL"
     gene            complement(40885..41661)
                     /gene="larB"
                     /locus_tag="PK679_01740"
     CDS             complement(40885..41661)
                     /gene="larB"
                     /locus_tag="PK679_01740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HPC54711.1"
                     /translation="MVPNRRLREVLTGFSDGRLTLEEAAAEIEGLRIEEVEDLARLDL
                     GRAARCGIPEVILAEGKAPVEIVEIARKAVQVSPRTIISRMSPDHARAIREACREMGV
                     SFTWHEKAAMGVLSRGSPIVPGKGIVAVISAGTSDLRVAEEARVIAEEMGCTVRTAYD
                     VGVAGIHRLFPAIRKCLDAHVFVVAAGREGTLPAIVAGLIDRPVIGVPVSTGYGYMGG
                     GQAALASMLQSCAVIAVVNIDAGFVAGAFAARIANMVGDR"
     gene            41712..42050
                     /locus_tag="PK679_01745"
     CDS             41712..42050
                     /locus_tag="PK679_01745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC54712.1"
                     /translation="MSYLVYVAAFGCGVVFFLWFRDMRIFARTALPGFRKAAYRGVLY
                     SALSLLGFFFTYTSGPAFPTELIGLGIILAALYLQGRVERERVFAGSDWWDRLLGKAP
                     RSTKHRTQEG"
     gene            42059..43294
                     /gene="hisS"
                     /locus_tag="PK679_01750"
     CDS             42059..43294
                     /gene="hisS"
                     /locus_tag="PK679_01750"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HPC54713.1"
                     /translation="MLQRPRGTRDFLPAEMEQRRSVENAMRRIAHTWGYREVCTPTFE
                     ELELFTLRSGEGIIEEMYVFEDKGGRKLALRPEVTASVLRAYVNVGKTLAKPLRWYYF
                     ADCFRYERPQKGRYRQFWQFGVELIGQDTPLAEAEVIMLAQDLLSASGITFTLHVGHL
                     GFMRALLGGLAPEDQKKVRILLDKKNYDGLSAFLSSRGESGLSDRLTALVECRKLDDA
                     LAITGDMPGKERIRELFSILDQAGVPYTLNPGIARGLDYYTGMVFEAFAENLGAENQV
                     AGGGTYRLAHLFGGEDTPSCGFAIGFDRVMVARGDIPGTPAVRVGIAHTPDARDWALH
                     VAAAFRSAGILTESDLSGKNLSQQIASISRNADFALIIGRREQEKGSVTLKDLRSGTQ
                     KELSLAQAIAEVNGDDSCR"
     gene            43278..45083
                     /locus_tag="PK679_01755"
     CDS             43278..45083
                     /locus_tag="PK679_01755"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase VI subunit B"
                     /protein_id="HPC54714.1"
                     /translation="MTLADELARQQRSISVAEFFEKNKHLLGFDSPTRGIITTIKEAV
                     DNALDACEEAGVLPDIYVRVTRTGPDTFRISVEDNGPGIVPGQVPFVFGKLLYGSRFH
                     QIRQSRGQQGIGISAAVLYAQLTTGLPTLVISRTGPEEAAFRFLIQIDIQTNEPVIIR
                     KEKIDWDRTHGTLVQVEFRSTIAAKKKLLEYLKYTSIVNPHARITVEMEGETTLFERV
                     SDEAIACPKTIMPHPHGIEIGQLMRMIAGSRAACGEFLVTSFSRVGKKTAHEICRAAG
                     ISPDTPVSSLSPAEQKKLLSAMQNAKVPAPTTQVCLSPIGEDLIVRSLEKEFQMDFVK
                     ARTRPGSVYSGHPFLVEAAIGYGGKLPADGNAIILRFANRVPLMYQQGACAITGCIAG
                     ITWKNYNVAQAGLPTGPLLIMVHVASTNVPFTSESKDAIAGIPEIEREVTLVLQELGR
                     ELKTYLSRRDKSRLAEDRARAVCAIIPDIASKVAEIVELPVPDTSLIEGRLMRRVVVK
                     KMSRNGHVTIEVRNHMATTNVLSLYDISRNPADDARPAPSFATELDGEYTRMWQLEIP
                     PGGVWTAEYSGTGGGTVQVRGIPPENIAVVDLDAE"
     gene            45115..46170
                     /locus_tag="PK679_01760"
     CDS             45115..46170
                     /locus_tag="PK679_01760"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011832794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HPC54715.1"
                     /translation="MAIAMQWYRQMAEGNIPSITLPTRTKQNIAYDDESEVWKLGDRE
                     SVRSAHTARSALHLLKMSYVIGFLKTQLRENRSSTLRELYYISEGWKKAKFSAQDESN
                     YLIEDLEILTDLQREAFHLRPEEDGATIFGPLRLKEMTRRGERIIHCRDDVGEAGYQI
                     PCNVENVELLDHDASCVIAIETGGMYARLIENGFDEEYRAILVHLKGQPARSTRRMLH
                     RLSDEFNLPVYVFTDGDPWSYRIYASVAYGAIKSAHMSELLATPKAQFIGVQPSDIRD
                     YNLPADALTEKDIAALQSELTDPRFGSSYWKEQIQLQLALNLKSEQQAFAARGLDFVT
                     REYLPRRLSEMGLVIRS"
     gene            complement(46157..47347)
                     /locus_tag="PK679_01765"
     CDS             complement(46157..47347)
                     /locus_tag="PK679_01765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HPC54716.1"
                     /translation="MGLKDRILGDPGREKPDKESGKTGVPPAQEKKEKQPFPPSPPSM
                     HATDSGGKAAGIGGLFSRKKPAGIDLSPAEIGKFAREQEEIIRKLEKVRAERSGVMRV
                     IKHPVAVLLEKPLNILIVSLPASIIVFVLGTALAIRDYGMGVLFSTTLVDDVVVFSIL
                     VAIVPVAVMDFRENRRIKNLEEALPNFFRDLAGMNDSGMTLPNAIHLVAQGEYSTLTP
                     FIRRLDNEMSWNTTFIEAIQRFRTRLGTPLADRSIDLIAKASKAGGDVSEVLRAAARD
                     TYEVLALRTERRNNMLIYVIIVLISFLVFVFVIFILVSTFLSTMATAGSAAESAGAGA
                     ASFIGNIDLFFYTRLFSHAAMIQGIFSGLVAGQMGEGRVTAGLKYSAIMLLISWIIFR
                     FMIG"
     gene            complement(47350..48273)
                     /locus_tag="PK679_01770"
     CDS             complement(47350..48273)
                     /locus_tag="PK679_01770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HPC54717.1"
                     /translation="MNSWERFAFRLFGTLAGKKRDKYAALRSDLVTARMKVPFEVYLS
                     TAYLSALFAGAVASVVLGIITFIFNIPSMIKYQGAVPEFMLFISEYSLIIGTIIAIVI
                     SFAVVGGITFVIFLVYPSVVAGNRRRNIDATLPYAINYITAMSTAGIPPAEIFRQLGN
                     SPMYGESAVEARFVAMEIDLFGRDLLDALRLISATTPSLRMKEFLQGAMGCISAGSSL
                     TEYFRTKAEQYSLENRQSQKLFLDTLGLISESYVTAMVAGPLFLIILQSIMSILSKSS
                     QPIFLYIIIYMMIPFGSLMFVILISSMTPEG"
     gene            complement(48270..50585)
                     /locus_tag="PK679_01775"
     CDS             complement(48270..50585)
                     /locus_tag="PK679_01775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="HPC54718.1"
                     /translation="MTGDSKKDGIFGSLFRRKKEELPGKGKKTEDSATSGQITGVGKD
                     DLDLLVKKLGISAPGKEKAPVRQSAKVTPLPDTGETTGGTPVPRMEKMPGVPAFQAER
                     SIPEIEPERKPQEQAAPPTRMQQDKGEESAGEGKEKPARAFPSPSFKPAKKVTQSREK
                     EQETEAIVSVDDIDDISGLILPKGATFQIDEIKISEKTDIFKFKGTVSDGQGKDLQKS
                     DLLEGSIRTVTDAATEVQAEAGSKTLLKKLNPLNVIRKVPVEYNMRTHGPLVDLKFRP
                     RPGVEEIEIYPVNEPYAYVRITYDNATHEYMYEVLEPKLTPAELDLFNDIKERIFERL
                     DINTQNVIEEVAKKTLRDVTDDIIADYGISLTPVQREKILYAMYKEFLGNGMIDPLMH
                     DRYIEDISCDGVNANLFVFHNRYESMRTNLVYKSAEELDSFVIKLAQRSGKYISIAEP
                     MLDATMSDGSRIQMTLGSEVTAHGSTYTIRKFKDEPITPTDLIEWRTFSPLAIAFFWL
                     AVESGKSCIFAGGTASGKTTSLNAISLFIPPLAKIVTLEDTRELKLPHPNWIPSITRT
                     SFDASGKGEIDMYELLRAALRQRPEYILVGEVRGKEALTLFQAMSTGHVTYSTMHADS
                     VASIVHRLENPPLNVPRNMLSALDLISVQVQARVGGQRIRRNKQIIEILDIDPRTNEL
                     ITNEVFRWHPATDEITYSGKSYVLEEIMESRGWDEERMREELKMRQEVLEWMRLKKIR
                     HFRDVSNILIQYFRDPARTMEKVRAELYGET"
     gene            complement(50650..51345)
                     /locus_tag="PK679_01780"
     CDS             complement(50650..51345)
                     /locus_tag="PK679_01780"
                     /inference="COORDINATES: protein motif:HMM:NF015232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="HPC54719.1"
                     /translation="MKFPRGTYLGVVEDPLVDTVSGEKVPFSGKIEVFTTKGAGLFLA
                     KEGEVIAACYREKENEYHGSEAVTYLLKNMEGSSLEPRFIQYRYGPEEMALAEEMCFE
                     RGLSIKQAVKPKNVPRARLDDGVLARFMALQGVHAVLAFFEGFPVQTSGDGDFEHVAA
                     IAEDFIRTAGKVALDMNLGSPACVVIEGNQGTCVIAPYGDLSLCILADKTAHLGMIRL
                     AVTILHKEMFHSV"
     gene            complement(51351..51698)
                     /locus_tag="PK679_01785"
     CDS             complement(51351..51698)
                     /locus_tag="PK679_01785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="HPC54720.1"
                     /translation="MLKQILGEFLKIEGVSAAVVVGRDGFVIESAVSGKMDIDALGAM
                     ASTGLGTSEAMGKELGKGELRQMLVELDQGPIIMSPLSPDELIAIVAGNEANVGRIRY
                     ELKKNKDRLVAAL"
     gene            51863..52597
                     /locus_tag="PK679_01790"
     CDS             51863..52597
                     /locus_tag="PK679_01790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54721.1"
                     /translation="MQLPRGIFRSIEKGEKLGDFLKKLNSDQFSGVCSIVCEGHTIEI
                     VLEKGRFSLASCDNLSGDDAIGVIGGLMERPFDASISDLTPAQLKLSREFNEAFIVRT
                     SFTAEKSIQNPQFTKDESIPAAGKIPLQKPEYKPQTVIPARHQRKPQDQDALNVQVAK
                     SERNSIPKDSERTPATRNEALFETGEENINSPEQGYTLDDLDLKALDSMDLDVMSRKI
                     RDNCKLMVERLHLGYLVVDEDKKESG"
     gene            52594..53187
                     /locus_tag="PK679_01795"
     CDS             52594..53187
                     /locus_tag="PK679_01795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54722.1"
                     /translation="MKNMEVITFDLFLLITGLILVGIILFLSLVSVIYTVRLAYKMDT
                     LMKMIDTFRPVSKVDYSIPGIETKVKRGEPEISVKETVSVPEKPKFDPARDAPDIPSG
                     MHRLCEIYGIESLTLSTPDGLVVASTGHPSAGDDAARVSYASVTGTPVSEEGISVFHT
                     DYKGNALVGIIRGNREIPKDLLGELKKDINSLLQRWI"
     gene            53261..54046
                     /gene="minD"
                     /locus_tag="PK679_01800"
     CDS             53261..54046
                     /gene="minD"
                     /locus_tag="PK679_01800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATPase MinD"
                     /protein_id="HPC54723.1"
                     /translation="MVRVFTFASGKGGTGKTTATVNIGTCLAQFGKNTIIMDADIGMA
                     NLGLALGLEDVPVTLHEVLAGKANVQDAIYEGPAGVKVVPSGISLQGFQQANPELLKD
                     VLKDLVEVCDYLLIDAPAGISRDGIIPLAVADDVILIVNPELSSIVDALKTKILTEVI
                     GGHVFGVIINRAGIDKSEVMVQKMEKVLGVRVIGTIPEDPNIRKAASAKTPVVIKYPG
                     SPASVAIRNLAGELAGIPMEQRGGKSQEKFIERFSKVLFRGKK"
     gene            complement(54254..55813)
                     /locus_tag="PK679_01805"
     CDS             complement(54254..55813)
                     /locus_tag="PK679_01805"
                     /inference="COORDINATES: protein motif:HMM:NF028510.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cache 3/Cache 2 fusion domain-containing
                     protein"
                     /protein_id="HPC54724.1"
                     /translation="MKKEDFENILKGSKDITAYMHMNPAEGVTTCFGVRTASNPNFLV
                     RALYEMYEANLGKKLANKAMRKLFRSVGHGSVGLNKLLKKLGLNLKPEEFLMLVFTMQ
                     HQQGWGSPFELVEASEKRIVMRCKQTFESEVLKDWNMPVCGIHQGWIEGILSAITGKN
                     WFCLERSCHAKGDPFCEFVADQVHPSWKFKAEAVVRGDSAITEFIEHKPLEGRISLMD
                     EPVVMMPRFIFSSMTSSLTKTMGEASASGVNYRAYKDMGKENVEHYKKMSISFDLSRT
                     KLDQDLNELRKRFLAFGPPSISGDQLAFGNHIVNNNFEVVDSIEKELGSKATVFQKIG
                     DKAIRVSTNVIGADGKRAVGTEISSVVYDAVVKKGQTYYGTADVVGRKYVVAYEPIRN
                     SADNIIGILFVGTPEDEILGTYKEEVLKKTNPDTICNMAFTFYSQMGWFKIIKKEWNE
                     AEKTRTFTLEHTVESESIGNTGKNVCFCTAGLLAGIVEGAYNIKADAKEIKCRSKGDE
                     HCVFQVRNRPS"
     gene            complement(55969..56544)
                     /locus_tag="PK679_01810"
     CDS             complement(55969..56544)
                     /locus_tag="PK679_01810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54725.1"
                     /translation="MSLTHALSFARTHSFSGIGHAKEKQGDFYLLFLEGDPNGAVLHD
                     SKGALFGNKAVYLMKGTEQFTLFPVRPEIVERLILGCRIFDQEILRRILPVDIPEVKR
                     EREGGAGIFSVVIVDNGRPLAGHRVSIRKEGQVIGNDFTRADGKVSFRLLYGKYECVV
                     HSRDLTTRMYEFEFHPGLNNKPVTLDIGNVK"
     gene            complement(56579..>56765)
                     /locus_tag="PK679_01815"
     CDS             complement(56579..>56765)
                     /locus_tag="PK679_01815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54726.1"
                     /translation="PEELSWIQIYHELYRFICMAPKDSPRGGIGKNDPCLPGYGRFLS
                     GFDQEKEVVSPDKQGNS"
     assembly_gap    56766..56865
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            56874..56981
                     /locus_tag="PK679_01820"
     CDS             56874..56981
                     /locus_tag="PK679_01820"
                     /inference="COORDINATES: protein motif:HMM:NF018546.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HPC54727.1"
                     /translation="MSYGIPFLVPLTAGVISALLFGDILFFLIRFIAGV"
     gene            56983..57348
                     /gene="hisI"
                     /locus_tag="PK679_01825"
     CDS             56983..57348
                     /gene="hisI"
                     /locus_tag="PK679_01825"
                     /EC_number="3.5.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="HPC54728.1"
                     /translation="MLQLNYSDGLIPVIVQDARTRDVLMLAYANEEAISLTRKTGYAH
                     YFSRSRKKIWKKGEESGHFQRVSGILVDCDEDAVLYLVEQTGAACHTGYWSCFFRTID
                     GEIRGEKVFDPGRVYANKE"
     gene            57375..59258
                     /locus_tag="PK679_01830"
     CDS             57375..59258
                     /locus_tag="PK679_01830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PINc/VapC family ATPase"
                     /protein_id="HPC54729.1"
                     /translation="MIIVPDTSVVIDGRITSMIQAGEYKGATIVIPEAVVAELEAQAN
                     QGREIGFLGLTELQALCRLAAEGTIGLKFVGVRPTLDQVKLASGGEIDALIRSAAIEH
                     GAKFITSDIVQAEVAKAKGLDVIYLRPQVEGFAPLAIDQFFDEHTMAVYLKERVPPMA
                     KKGTIREMRLERIRDQPITDYELRNIAQEVLERAKRHPDGFIELEKRGVTVVQIGSMR
                     IAITRRPFSDGMEITAVRPIADVKLEQFKKAQIIKTRIIGDRRGLLVAGPPGAGKTTL
                     AQSIATYLAENGYVVKTMEAPRELQVPDHITQYTTLDGSMENTAEVLMLVRPDFVIFD
                     EVRKNEDFRVFADMRLAGIGMIGVIHAIGAHDALQRFSDRVDFGVLPQIINTIIFVDR
                     GEITNIYDIGFTIKVPEGMSSEINLRPVTTVSDHETGEIVFEIFKYDGETIVMPVMSP
                     VTSPAQALKAPSMPAKEENAQWKILEKDIQREIGRYTDGYVDVHMLSDTKAVVYIEDK
                     DVPAAIGKGGKNIAAIVNKVGIGIDIRPRSELEKTAAAAPVEEELHLGGGVKIRMDKK
                     QLAISCPEQSGKIVDVFAGKEYLFTATVSDSGEIHLAKNSTIAQELIKRYNDGDTIRL
                     RPV"
     gene            59298..62078
                     /gene="leuS"
                     /locus_tag="PK679_01835"
     CDS             59298..62078
                     /gene="leuS"
                     /locus_tag="PK679_01835"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HPC54730.1"
                     /translation="MNLPDFGQLERDCLHAWDHAFEANPAGKEKFYLTVAYPYPSGAM
                     HVGHGRTYIVPDVIARFWRMRGREVLYPMAFHVTGAPVIGISKRIARGDEKAIRLYRD
                     LYKVPPETLKQFVDPLTIVRHFSDEYQRVMSACGLSIDWRRRFTTVDPQYSKFIEWQW
                     KHLHEGGHVKKGAHPVRFCPQCDNPVGDHDLLEGDKAEIQKFVLVMFRWKDAFIPTAT
                     LRPETIYGVTNLWVNPEVTYVRARVDGVPWIVSREAAEKLSFQDHTVTVEDEIPGSSL
                     VDETVSHRLCGNVPILPAKFVDPGMATGLVMSVPAHAPFDYIALRDLQSKGLYAHIRP
                     VRLITVPGYGEFPAKDAVEKAGISSQDDPRMDEITQQVYSAEFTSGRLLPELGGQTVR
                     EARESVAALLIENDSSRYMYEFDTRPVVCRCGNQVFVKILHDQWFLEYSDPAWKALVS
                     RHLEDMTLVPPEVRAEFERTVSWLKDWACTRRVGLGTRLPWDPDWLIEPLSDSTIYMA
                     YYTIAHHLKEFSPEELTPGVFDYLFLGKECPDHPRREKLVQMRREFCYWYPYDYRFSA
                     KDLISNHLTFQLFHHVAIFPRTCLPRGMVVFGMGLLNGAKMSSSKGNVFLLEDAVREF
                     GADTVRMFLVGSAEPWQDFDWRNELVSSTRKQIERFYNTIMESRDAPRTMSLADAWLV
                     SRLQQHIQRTTEALERFQTRQALQEAFFAIESDLKWYRRRLVPGTPGGGALHELASVW
                     MRLMAPVIPFTCEKLWKESGGKGLVSYAQWPVPEQAKMNGDLELAEELLMRTIEDIES
                     IQKVLQATPSSLSLCIAPAWKRDIFSRVARADDRNAVMRDIMKDEQVRKMGKTAAETI
                     KQCTSLVHRLPPAIVEQYLAGKLDEKAVFLSARDFIEKEAGVPVTIVDADESAHPRAK
                     LALPLKPAIIFE"
     gene            complement(62090..62407)
                     /locus_tag="PK679_01840"
     CDS             complement(62090..62407)
                     /locus_tag="PK679_01840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5611 family protein"
                     /protein_id="HPC54731.1"
                     /translation="MQEYPVKRGYYRDLPGSIARSLRDCFGVEPVRVGDHYQLSYGAL
                     RLLDAAPGKDGKTLVVHTESDIGAPDEVILDTNKRFRAFLDAVTGYSTKERVKRAKSV
                     ETE"
     gene            62443..63171
                     /locus_tag="PK679_01845"
     CDS             62443..63171
                     /locus_tag="PK679_01845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome assembly chaperone family protein"
                     /protein_id="HPC54732.1"
                     /translation="MSPESKPDIKIYSRSLSGPGSTVLMGFPGSGLVGSIALQYMVDQ
                     LNFEQIGSINSKYFPPLAMMNKGVINVPVRVYEKGNISAIVADIPIHPMICYEVANGI
                     MDWLEPFAVREVVTIAGIITNEPEKRVFGVASSEEALQRIQDSTIVLPIGSISGIASS
                     ILTECKIRNIPAFGLLGETINAPDPRASAATIEVLNKMYGMNLDVQPLIEQAEEIEST
                     MQKLAEQVKSAETMPKKEHLPMYG"
     gene            63177..63569
                     /locus_tag="PK679_01850"
     CDS             63177..63569
                     /locus_tag="PK679_01850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF473 domain-containing protein"
                     /protein_id="HPC54733.1"
                     /translation="MQCYALTGISPQIIRELREGKARTLELQSTHNVVTLAGISPGEL
                     VFMTSVDLEDLSPGDTGIVVEVLSLNITMKRIMEYSHGLHYEERERMSARIKVKCIGA
                     STVKSVTVEGFTRPIVVDVMKTACYHAG"
     gene            63705..63779
                     /locus_tag="PK679_01855"
     tRNA            63705..63779
                     /locus_tag="PK679_01855"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:63740..63742,aa:Arg,seq:tct)
     gene            63934..64185
                     /locus_tag="PK679_01860"
     CDS             63934..64185
                     /locus_tag="PK679_01860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54734.1"
                     /translation="MKEGCLETDNTIMTAIAEIEDAFFDIESIKTDIRNIQYDLAELD
                     RKLQAVTVHLKEVQSFLGTVCAVPPTESGGAPQEKSFRL"
     gene            complement(64352..64798)
                     /locus_tag="PK679_01865"
     CDS             complement(64352..64798)
                     /locus_tag="PK679_01865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusA-like transcription termination
                     signal-binding factor"
                     /protein_id="HPC54735.1"
                     /translation="MVEVLLNEDCMRLMSQFEKLTGAGSRDCVIDDRNNRIIFVINPG
                     EMGLAIGKSGASIKKAMEVMGKRIEVVEYAQNPEQFIRNCFLPAKVTSVVFEGEGDAQ
                     VAQVEVREEDRGLAIGKEGKNIFKAKKLAQRQHNISDVLLVNNQQP"
     gene            complement(64804..65094)
                     /locus_tag="PK679_01870"
     CDS             complement(64804..65094)
                     /locus_tag="PK679_01870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30e"
                     /protein_id="HPC54736.1"
                     /translation="MDFNASLRRAIKTGKVLLGQNVTAQCIESGSARMVVVARNCPEK
                     FLEMLKSRENLFVHTFDGSSVQLGKACGKPFMVSALVVVDPGESDILSLKRA"
     gene            complement(65094..66269)
                     /gene="rpoA2"
                     /locus_tag="PK679_01875"
     CDS             complement(65094..66269)
                     /gene="rpoA2"
                     /locus_tag="PK679_01875"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit A''"
                     /protein_id="HPC54737.1"
                     /translation="MQPEFEEAITAAELPEKTKEQLRTYLADRDITREQFDTILDRVI
                     REYANTRIEACEAVGIIAAQSIGEPGTQMTMRTFHYAGVAEINVTLGLPRLIEIMDAR
                     KEPSTPTMTIYLEGEYATDRDRAREVSWQIEAAPLHEFGDIVIDMENMQIVVQLNTQV
                     CEKRRIAVSDIIDSAPRKIRDRRHYRDFECEVDVNNATMIFSPKDRESYQNLFQLAEH
                     VRNVIVQGIDDIERVVVRKESGEYILYTEGSNLKDVFEVEGVDTTRTRTNNISEIAQV
                     LGIEAARNAIIHEALSTLSEQGILVDVRHIMLVADMMCMDGEVKQIGRHGIAGEKESV
                     LSRAAFEVTVNHLLDAAIANEVDELSGVTENVIVGQPIQLGTGDVKLIAKPLKLGES"
     gene            complement(66271..68910)
                     /locus_tag="PK679_01880"
     CDS             complement(66271..68910)
                     /locus_tag="PK679_01880"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit A'"
                     /protein_id="HPC54738.1"
                     /translation="MPSPKRIGKIEFGLLSPKEIRTMSVRKIIWADTYDDDGFPYPQG
                     LMDLNLGVIDPGLRCKTCDQKASDCPGHFGHIELAKPVIHVGYTRLIRKLLRVTCRSC
                     SRLLLSPEEIEKVVGTEDDLTGDVLSEKDIKKERVCPYCGEQQLKINFEKPTTFSEII
                     IEDGKKIEHKLTPADIRARLEKIPDEDLRHLGINPDVARPEWTVLTVLPVPPVTMRPS
                     IILENGQRSEDDLTHKLVDIIRINQRFKENQDAGAPQLIIEDLWELLQYHVTTYLDNE
                     VAGCPPARHRSGRPLKTLSQRLKGKDGRFRGSLSGKRVNFSARTVISPDPNLSVMEVG
                     IPLAVANEMTLPVTVTPYNIEELRQMVRNGPVRRSLSQPCGANYVIRPDKRRMRLAEG
                     NLETVAEMLEPGWVVERQIRDGDIVLFNRQPSLHRMSIMAHRVKVMDGRTFRLNPAVC
                     PPYNADFDGDEMNLHIPQTEEARAEAAILVAVEENILSPRFGGPIIGGIHDHVSGIFM
                     LTNQLKWHTKQEALYLLKNIEIEHLPPPGMVKDGVPYWSNKQIFSIVLPKELNMVFRA
                     SSCQNCETCKRQECDRDAYVRIIDGNLESGTIDKKAIGAFDGQIVNRIIRQYGMKRAA
                     DFIDDITHLAIRAIMMNGFSFGIDDEDLSKTEYGQIEEVLRNAITDVQRRIRIYEDGQ
                     LEAMPGRTPEETLEMQIMQVLGKARDRTGEIAGRHLGLGNSAVVMAVSGARGSMLNLT
                     QMAGCVGQQSVRGERIMRGYDDRTLPHFRKGDRGAAAHGFISHSYKSGLNPTEFFFHA
                     IGGREGLVDTAVRTSQSGYLQRRMINALQDLKVAYDGTVRTTGGRIIQFCYGEDGTDP
                     MKSSFGDPVDVKGIVESILKEEV"
     gene            complement(68922..70736)
                     /gene="rpoB"
                     /locus_tag="PK679_01885"
     CDS             complement(68922..70736)
                     /gene="rpoB"
                     /locus_tag="PK679_01885"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit B"
                     /protein_id="HPC54739.1"
                     /translation="MKKARVFVDGALIGLVDDPKTLVSQIRTMRRQGLLSTEVNVSHK
                     EFNNDVVIHTDRGRARRPLIVLSQGKPLVTVEDIEKLRKKEIDFDNLIRRGLIELVDA
                     EEEEDLYIAINPEDITPEHTHLEIDPSLILGIGAAHVPFPEHNASPRVTMGAGMVKQA
                     LGFGAANMKIRPDTRGHLLHYVQKPLVHTQTSDLIGSDDRPAGQNFVVAILSFEGYNI
                     EDALIFNKASIDRGLGRSHFFRTYEGEERRYPGGQVDRIEIPDEEVTGAHGAESYKNL
                     DDDGIINPETVVNEKDVLIGKTSPPRFLEEPTSDLITVEKRRDTSVTMRSNERGIVDT
                     VIITEGENSSRLIKVKTRDQRIPEVGDKFASRHGQKGVIGLITPQEDMPFTESGLTPD
                     LVINPHAIPSRMTIGHMLEMIGGKVGALEGRRVNGTAFSGEREEDLRASLKKQGFAHT
                     GREVMYDGITGKRFSADIYMGVIYYQKLYHMVSSKMHARSRGPVQVLTRQPTEGRARE
                     GGLRFGEMERDVMIGHGAAMALKERLLDESDKVQEYVCARCGMVAMLDRKSNTTRCLA
                     CGAETDIYQVEMSYAFKLLLDEMKSMGIAPRLKLEDVV"
     gene            complement(70733..72292)
                     /locus_tag="PK679_01890"
     CDS             complement(70733..72292)
                     /locus_tag="PK679_01890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit B''"
                     /protein_id="HPC54740.1"
                     /translation="MIDRSVLSKAYFSQEHVARHQLDSFNNFLTQNLQKVVNEQRVIE
                     TDIEIRGRSNEPVWVELGRVEVKKPLVREADGSQGDLFPSEARLRNLTYAAPIQLELT
                     LVQGQDRQEPVITTIGQLPIMVGSVACNLYGMSPEERIAHGEDPFDPGGYFIVNGTER
                     VLMTLEDLASNKIMTEYTERYNERIYVAKVFSQYRGYRALVVVERNRKNLLEVSFPSV
                     AGHLRFVDLMRALGMVSDHDIVSAVSTDEDILTFMMQNLEESECDSVEAGIMYVGKKL
                     APNQTRDYQRKRAEFVLDNYLLPHLNYLMPTNLKEGEEGYKEAVAEVRLAKAHFLGRM
                     AEACFDLVLAKRRIDDKDHYSNKRLKLAGDLMEDLFRISLNRLTRDIKYQLERASMRH
                     RDLSIGTAVRADVLTERLLHPLATGNWVGGRTGVSQLLDRVDHMSVLSHLRRVISPLS
                     RSQPHFEARDLHPTQWGRICPSETPEGPNCGLVKNFAQMVEISRGVPDEEEVIHTLYS
                     LGVEHIKGDAL"
     gene            complement(72320..72571)
                     /locus_tag="PK679_01895"
     CDS             complement(72320..72571)
                     /locus_tag="PK679_01895"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit H"
                     /protein_id="HPC54741.1"
                     /translation="MSIKLNVLEHIMVPDHKIMSEEEIQHLYSLYHITSEQLPKIYHD
                     DPAVKAIGAKVGDVIRIIRTSHTAGRAESFRLVVKRPKK"
     gene            complement(72645..72718)
                     /locus_tag="PK679_01900"
     tRNA            complement(72645..72718)
                     /locus_tag="PK679_01900"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(72682..72684),aa:Lys,seq:ttt)
     gene            complement(72837..73544)
                     /locus_tag="PK679_01905"
     CDS             complement(72837..73544)
                     /locus_tag="PK679_01905"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC54742.1"
                     /translation="MEHTILIVDDNRFIVEGLHAILRKRGFRTISAMSGIEALDLLSR
                     GVPDLVLLDISMEPIDGWETLRRMRANPDLVQVPVIVFSARRTLSEEASYHHLNVSEV
                     LTKPINTSLLLDVITRILSREDEAGGKGSEGEASKSKAGDGSEDAGPGEEAQSEGVPP
                     DLGRTGSVTGEENLEKAEEKAGSTDIEIKSQEDVTGPVVQEPGRDTETEKKGKKSLDA
                     RLLEFHISLGFEKHLSE"
     gene            73709..74854
                     /locus_tag="PK679_01910"
     CDS             73709..74854
                     /locus_tag="PK679_01910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54743.1"
                     /translation="MVQLAEWLGELSPSFSPKPTTVQRAARHLSKMERAKLLSADIDK
                     MRTAEGRWYEAIIYETFIDLATRSDSIRYLALKGADAPRRRRTARLGQNGIFYSRSGD
                     ITIRGNGQDLAEFDLLMVDGENRITFAEVLTSPSDLKEFEVEIEYKRNLLGYLFDQQE
                     VPFLLVSSFNVANYSAGRRIIRSPYTYYFQTESCETIKTRIDTRQLTKRPVWDFTPHA
                     KMVDAAGFSFRRPFDYQKFHDWQRNWVFSNVSNEIDVKKVKNPHETAPLVKKILYGSL
                     YPSAVRRVCEDYEFSIRGKKVAFNDIRKKYSKVILATDLPGYEPLIYLRSREKREYLK
                     MVQDRDGNFKFERNTPPRVGFFLWLESLTPTLGSRIASKILEAFSPR"
     gene            complement(75006..76595)
                     /locus_tag="PK679_01915"
     CDS             complement(75006..76595)
                     /locus_tag="PK679_01915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="HPC54744.1"
                     /translation="MNLRQPNANEATGTTNRSRNVAPVSGICTRCVDGCKGSCEIWLS
                     SFRGREVLYPGPFGEITAGADKNYPVDYSHLNIQGYAMGARGLPEGTEIGPDSAVFYS
                     VNTETEYGWDKKVRMKLPIFTGALGSTDIARINWEHFAIGAAISGITIVCGENVCGVD
                     PALQLDNHGKVKKSPEMDRRIEIFRKFWDGYGEMLVQMNVEDTRLGTAEYVASRHNLE
                     TIELKWGQGAKCIGGEIKVKTLERALELKKRGYIVLPDPTLPDVQAAFKAGAIKEFER
                     HSRLGFISKEGFLEEVDRLRDIGFKRVTLKTGAYSAVELAMAIRYGSEAKIDLLTIDG
                     APGGTGMSPWPMMNEWGIPTFYLQSLAYEYAELLKKRGLRVPDLAMAGGFSDEPGVFK
                     ALAMGSPYFKAVCMGRGLMIPGMVGKNIEKWLKDGDLPKTVSKFGSTPEEIFVTWEEL
                     REKYGARFKEIPMGAIGIYTYAQKFRIGLQQIMAGSRNFAISSISRSDVMALTEEASR
                     ISGIPYVMDAYADEALTVLLD"
     gene            complement(76822..77943)
                     /locus_tag="PK679_01920"
     CDS             complement(76822..77943)
                     /locus_tag="PK679_01920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HPC54745.1"
                     /translation="MPQKVYFTRVGGRDPGQNTLSKINRLFHAAGFPDLISQGDLTAV
                     KIHFGEWGNDSYINPVHVRQVVDCIRETGGKPFLTDSNTLYRGSRANAVDHLVTAIEH
                     GFAYAVVRAPLLIADGLRGKNWRRVEVHLRHFPSVFVSGDIADADAMIVLSHFKGHEV
                     AGFGGAIKNLAMGCAPPAGKQAQHCARPMHIDERCTGCGRCIAVCPGEAITFEKKRKK
                     PRAKIQYSRCIGCFECMTVCPSHAIDVDWETEIPEFVERMVEYARGAVSGKEEKAGYM
                     NFLVNITPDCDCVPWSDMPIVPDIGILASKDPVAIDAASFDLVNGEKGREGSFLHENL
                     REGEDKFRGLRKNTDGYLQIRYGGEIGLGSREYELVSIS"
     gene            complement(78350..78838)
                     /locus_tag="PK679_01925"
     CDS             complement(78350..78838)
                     /locus_tag="PK679_01925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HPC54746.1"
                     /translation="MLKKSIEEALNKQLNAELYSAYLYLAMSAYCETIPMKGFAKWLR
                     IQSEEEKAHGMKFFDYIIEAGGTVKLARIDAPKAEWKSVGEVFEQVYEHEKKVTGMIN
                     GIMDLAVKEKDYATQNFLAWFVKEQVEEEANASEILAQIRMLKDVVGHMFWLDHELGK
                     RE"
     gene            complement(78970..79722)
                     /locus_tag="PK679_01930"
     CDS             complement(78970..79722)
                     /locus_tag="PK679_01930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54747.1"
                     /translation="MKVTMKYSWQVKLGIFLVFFSFSVYFLKFIILGDPENTYFYVFN
                     ALGFLPINVLLVTLVLNELLSTRARRERLEKLNMVIGTFFSEMGTDLLHAIARKDPDI
                     ARVADALTIREEWSDQEFERTKKVFSSYPFRVLPERQDLESMRAFLKEKRNFLLRLLE
                     NPMLLEHQTFTELLRAVTHLGEELARREDLRAIPDSDVAHLQKDTERVYRLLCFEWLA
                     YMHHLKRNYPYLFSLAIRTNPFDPNARVIVGQ"
     gene            complement(79774..80901)
                     /locus_tag="PK679_01935"
     CDS             complement(79774..80901)
                     /locus_tag="PK679_01935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54748.1"
                     /translation="MEKQEENSMSLEKGDEGFMKWQEEDLATRLPHVMQARKEAGLDG
                     LVGDLEAVVINTERERLESAVAELLAFTGLTIDEQFSTPLVRAYTLRTPGSPAVIVKS
                     RLAGENPFLPFNQAERARNLPSTRLETFIFGCRDIDTYWEIQRERSVRFQTDGIITGP
                     DFRFIQTVPSPYTGNSLGFIEWTGRGRSFAPDGAEKRPATLEKPGFSYLANIGKLDHT
                     ATRVRAKERNAAILEFLSLTSYHFDFAVFVKSLNSITSVARLNDDAFAMVFTSGIAPY
                     REGEDPGPTENFIHGYGTRVHHMAFSTDDIDTVFAELVSHGMEFLVALVGSREEGLKQ
                     TFSMPSPHTMIVNEYIHRYEGFDGFFTRSNVEELTRATGRQ"
     gene            complement(80999..81142)
                     /locus_tag="PK679_01940"
     CDS             complement(80999..81142)
                     /locus_tag="PK679_01940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHS domain-containing protein"
                     /protein_id="HPC54749.1"
                     /translation="MAIDPVCRMTVDEKTARFRTEYRGKTYYFCAPGCKKKFDADPEK
                     YAA"
     gene            complement(81132..83594)
                     /locus_tag="PK679_01945"
     CDS             complement(81132..83594)
                     /locus_tag="PK679_01945"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HPC54750.1"
                     /translation="MTQEDEKRSAELRISGMSCATCAVNLEKALKGEGRVESATVNLA
                     SETAHVAYKPSITNLADIEAAVRKAGYQVVYDQATIKVGGMVCATCVETIEAVLKALP
                     GVAGATVNLSTEKAYVVYNSSITTIDDMKKAIEDAGYQYLGLADQVTTGAEEEARRRD
                     LGDKARRFLVGFGISIPEFILMISQPPLSPHTLSFLMLVITTPAFAYVAYPIYRGAVS
                     ALRNRTLNMDVMYAMGTGVAFGASVASTVGIGLSHDFMLYDTALMLASFLMLGRYLEA
                     RAKGRTTDAIKALIGLRPRTATLISDGEEKEVPIEDVRVGDLIRVTPGEKVPVDGTVI
                     AGESSVDESMVTGEPVPVFKAPGSTVIGGTINTNGVLTIRAQKVGKETVLARIIALVE
                     DAQASRPPVQRIADGVVAYFIPVILAIAALTFLVWFLVLGEPLTFSLTAFVSVLVVAC
                     PCALGLATPTAVTVGIGRSAELGVLIRNGEALEVADRVNSVVLDKTGTLTEGKPVVTD
                     IVPLNTQGATLLSLAAAVEKNSKHPLARAIVDAAAAGGAPPLDAEEFYLHGGKGVSAR
                     VLGEQVVIGNAAFLEENGIHLPTDAEETISRLGKEGKTVVAVATGGTIAGVIGIADPM
                     RDTSPDAIEEFRRMGLSVSMVTGDNIRTARAIAERLKIENVIAGVLPEEKAREVRKMQ
                     ESGRVVAFVGDGVNDAPALAQADIGIAIGGGTDVAIESGDIVLIRDDLLHAVAALQIS
                     RKVMARIRGNLFWAFAYNVALIPLAAGVFFPFTGYMLQPELAALAMAASSVTVVTLSL
                     TLKRYIPPVLRDRLPGGKNHGH"
     gene            complement(83944..85185)
                     /locus_tag="PK679_01950"
     CDS             complement(83944..85185)
                     /locus_tag="PK679_01950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HPC54751.1"
                     /translation="MTQGTFLPPGPVIVLLVVFILIAVRQVGRFRFRIWQVMCMGALA
                     VLFLGEISPRDALFAINPDVMLFLLGMFIVGEALEESGYLHVLAFRLFSKARSGRQFI
                     LFILVFMGLLSAILMNDTVAIIATPVVIAYACRFGLPPGKALLALCFAVTTGSVPSPI
                     GNPQNLLVATYSQLPQPFLTFLVYLGLPTAISLAVTYLLLTYDVGEGKFECSFDERQD
                     RIRNKNLARISRISLALIILLIVVRVITGPFLIPLSVIALAGAAPIIILSRERVKIIK
                     TIDWPTLAFFAAMFVLMQSVYNTGIFQSGIDFQSLTSIPLILSTSVCISQFISNVPFV
                     ALFLPLIMKEGMPVASLMALAAGSTIAGNLTILGAASNVIIIENAEKKGYTITFFEFI
                     RIGLPLTLAQVIIYAVFLAIL"
     gene            complement(85203..85886)
                     /locus_tag="PK679_01955"
     CDS             complement(85203..85886)
                     /locus_tag="PK679_01955"
                     /EC_number="1.1.1.302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone
                     5'-phosphate reductase"
                     /protein_id="HPC54752.1"
                     /translation="MQRPHVIVNLAMSADGKISTRERRQVKISGKNDFSRVDRLKAEC
                     DAIMVGIGTVLADDPSLTVKSQELVAARTGRGLPGNPVRVVVDCRARTPLDAAILHRG
                     PGRRIIACCEGSDRKKREDLSALAEVIVAGEREVDLPVLMQGLWMRGIRRLMVEGGGR
                     LIGALFAAGLVDEFITFIGNIVIGGENAPTPADGPGFVREEDFPRLTLFAADRIDNGI
                     LLHWVVEKN"
     gene            complement(86061..86984)
                     /locus_tag="PK679_01960"
     CDS             complement(86061..86984)
                     /locus_tag="PK679_01960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF475 domain-containing protein"
                     /protein_id="HPC54753.1"
                     /translation="MDPFSAILIIAGLVLFETITSIDNAIINAEVLSTMKEWARRWFL
                     LWGLLIAVFIVRGVLPWLIVWMSTPSLGPFGALTATFSSDPSVVAAIEESAPVLLMGG
                     GTFLIFLFFHWIFLEPKFYGLRGERYIATKGVWFFAVVSVLLSLLVWEALKVNPMMAF
                     GAVVGSTAFFIVHGFRQNAEEQEKKMVGGDMSDISKIFYLEVIDATFSIDGVLGAFAF
                     TLSVPLIIIGNGMGAFVVRELTVRNVENIRKYRYLKNGAMYSILVLGIIMVLDSFGAH
                     IPNWLSPLVTFGIVGFFFYKSMRYVALREGE"
     gene            complement(87133..88308)
                     /locus_tag="PK679_01965"
     CDS             complement(87133..88308)
                     /locus_tag="PK679_01965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Coenzyme F420 hydrogenase/dehydrogenase, beta
                     subunit C-terminal domain"
                     /protein_id="HPC54754.1"
                     /translation="MGLFGGKPDVKKGDMVYAWTSDADIAKKAECGGAVTSLLKYALE
                     HKIVDAVIAVKKGQDVYDAVPVLVTDPGQLKDTAGSLHCGTLLLAKVAQKFMERSKGM
                     KVAMTVKGCDVMALHELARRQKIDLNNLLLIGVNCGGTVSPVMARKMIKEKFGVDPDT
                     VTKEEIDKGQFIIEYEGGHKGIKIDDLEDEGYGRRSNCRRCLYKVPRQADLACGNWGV
                     IGDKAGKATFVEVCSEKGADLLARAVKDGALKTEKPDPKGLEMRGKVEGAMIKLGEKW
                     RKKDFEALSKDLWGTIRKETSRCIKCYSCIENCPVCFPSGGALKAKDLVVKPGEVPPN
                     PMFHLRRFAHISDSCVNCGQCEELCAMDIPLAKFSHAIRVEADMVFEPKLGKPAYSN"
BASE COUNT        18850 a        25289 c        23285 g        20863 t
ORIGIN      
        1 cctggattcg tgtctcagaa tccatctccg ggctcttgct ctcacaaccc gtaccgatca
       61 aaggcttgtt gggccgttac cccaacaaca acctaatcgg ccgcagaccc atcctcaggc
      121 ggcggacctt tcgatcaggg ggcattccag cgtccctggt ctatggggta ttatccccag
      181 tttcccgggg ttatccccca cctgagggta ggttatccac gtgttactga gcagtgcgcc
      241 gaggtcttgc acctctcgac tcgcatggct taatcgaacc ccgatagcag tggcctctgg
      301 caggatcaac cagaattctc gatcaacttg gcacactatt atcgcttact tcgaggaatt
      361 agcggttacc aaacaaattt ccgcattgcc agtaccaacg tcagaaccaa tggtcagcac
      421 gagtgctgcc gtgcttggtt ctccatcaca gagggtaata acataggtct tgtagatatt
      481 taaccttttt tccccggatc atatccaagg gaaatcagcc acaatcaggc tgatttcaaa
      541 ggttaccata cctcccggga gacgatcgat ccaacccccg cgatcgttgc atcgcgtacc
      601 ggattgaaca aatttcccgg cctcatttct cggaacagga ctgttcgcgt cttcctgttc
      661 ttcacatgat atgagatacc aatgttatct cccctcttat atcaattttt tcaggggatc
      721 ctcccgggaa atataaacag gaacgcgcga acggtaccct tcctgatatc cgttgaaacc
      781 ggacatcaaa tggaccccgc atcacagggt ctcatgactg ttccgggaca acagagtcct
      841 gcgcgccccg gatgccgaca aaaacctggc cgaagaactc ctcctgccag aggagaatct
      901 tctcctcgaa catgaggtag aggagaggga tatacacatc gatgattttt tttcccatca
      961 gcgctgcgat ttcttcgagc gtcatgacac cctcccgctc gatcctctcc ccgtactggt
     1021 caagaatgtc gtgcgcagca tcacggtatc cttcatcatg cgcgatgcca acgacatcat
     1081 ccacttcgat gagtgtcggg tcaaacccgt ggatgaacct ctgccggcgt ctctgctccc
     1141 tctccgcagc cttgagttcg aggatcagct caaaaagggt gatcgggcgt tttcgcagct
     1201 gtttcctgtc cagcctccgc ttgatctcac gctcgagacg ttctattggt ccaaggacat
     1261 tttctccggc ttcgatatct tcatcgaacc tgaaactgtc ctcttcgtca gcgcctccct
     1321 cgtcgtagtc ctcctccccg ggaagtcctg cctcttccag gtactctgac ttcatcctga
     1381 ggaggagtgc tgcataaaag agggtccttc ccgatatccg gagatccagt tcctttcgac
     1441 gttcgagctc ctggaggaac ctgtcggtga cctccacgat atcgatgttc caggggtcta
     1501 tctcacccct ctctgccatc tgcaccagta tctcgacagg ttcctcaggc atgggacttg
     1561 atccctgtga caaaactgct cttgtcggga aggagcgtga ccccgaggat ccggtcagca
     1621 ccctcgatca tgggtttgcg cagcgagaca atgatgaact gcgatgtttg tgcaagctcg
     1681 cggatcattg ttgcaatcct ctccacgttc gacccgtcga gtgacatgtc cacctcgtca
     1741 aacgcgtaga atggcgccgg gatgtactgc tgtatggaga aaatgaaagc cagcgtggtc
     1801 agtgacttct cgcctccgga cagcgcggag aggaggtgca cgggcttgtc gcggggctgg
     1861 acggcaaagg ataatccgcc ggagaaagga tcttcctcgt tttccaggac cagatggccg
     1921 ctcccgctcg tcagacgggc gaatatctcg cggaagttag cgtcgattgc gcgaaaagca
     1981 gtcatgaaag cctcgaactt catcttttcg aaacgctcta tccgctcgag caggttctcc
     2041 ctctccctgg aaagtacctc ctttttctcg ttccgctcgg tgatcctttt ttccacgcgc
     2101 tcgtactcct cgatggcaag catgttgacc gccccgattt tacgtatctc cagcccggct
     2161 ttcgcaatgc catcctcgat ctcctcgagt gtcatatcgg tatccatgtc tccggcctgg
     2221 ctccggagat cttccacctc gcgggaaagg gcgacgaaac gctcgttcaa tgcctccagc
     2281 tggaccctgt ggcgttcggc ggtcgcatcc agggcaagta tcttctcacc cgattccttg
     2341 atcgcaaggg atacccggtc atggcgatcc cgaagttcct ggagttcgct tgaaaactgt
     2401 ttctgccgct cctcgatccc ggctattttt accttgtttg cttcaatctg ttccgtagag
     2461 agggctatct cgcgatcaat atccgcattt ctcgctgaaa ttctctcgat ctcggctttg
     2521 agctcctcga gccgggagga gaagtgctgg cgttccctgg ccatgtcatt gatatcagat
     2581 tccttgttcc gcaggcgcct ctctgcctcg tccctctccc tcttcttctt ctcgagctgt
     2641 tccgagagtg cagggatctg ggtgtcctcc agctttttct tgacctggtc gatcttcttc
     2701 tgtgtctgtg caactgtatc ggttatcctg tccagggcag cctcgagtgc ggcaagttcc
     2761 gctatgcccg accgcatctc ttcctcgagc gaggaaatgg cttccccgat ctgggttttc
     2821 tccctctgga aaacctcttc ccgacgggtt atttcttctg tcacaattgc aaggcgcgag
     2881 atctcagcat cgatctcacc cctcttcgtc ctcagttcct ctatctcgcg ggtgccgctc
     2941 tttatctcct cctcaacctg cgcaatctct tccgacagat tctccatgcg ggaacgcaag
     3001 cgtgccacct cgtcctcgac cgctgcccca aagcccctcg ggggtttcct gaatgatcct
     3061 ccggtcatag ccccgctctt ctcgaggagc tcgccttctg ttgtcaccat ccggtatttg
     3121 ccgataagtt tccttgcctg tgcaagtgac tgcatgacaa cggttccccc gaaaacaacg
     3181 cggaaggctg cggcatactg cggggggaac tcgagcatat ccacggcata cccaatcatg
     3241 cccggttcct tcaccggtgg aaggtcaggg ggtttcaact tcgtgagagg aaggaacgtt
     3301 acccttccca gtttctgttc cttgaggaac tcaatggcac gggctgcaac cgtatcatct
     3361 ttcaccacta cgtaatgcag ctttgacccg gcagccacgt tcagcgcagt cgagtattcg
     3421 ggggatgcac gtccgagctg tgcaatggtt ccataaacac cctccatccg gagaattggt
     3481 tcaagggccc tgcttcccgc ctcacccctt acctgctgct gtgcctcgag cctgatgacc
     3541 tcctgctcgt actccctgaa ttcttcgcgc aacctttcga gggaggttct ttttgcaaag
     3601 acactgcttt ccctgtcgga gaggatccga tcgagacctg ccttctcctt ctcgagcctg
     3661 cccttctcct gaaggtttct ttcaactgcc tcgtccttct cctggtactc gagtgtaagg
     3721 gccccgaggc gttcctccag tcgctccttc tctgatgtcc tcatcctgct ccgctcaagg
     3781 agcatgtctt tctggtgaag gagggtcgat cgttctccct tcttcgcctc gacttcctgc
     3841 atgagcgaga agagttcgtc acgtgctccc tcggcatcgc ggctctggga ctttatctgc
     3901 tcctcgatct tcccgacctg cgccgtgagt gtcgcaacct ccatggccag gttggtccga
     3961 tcgatggtca tctccctgat cgcctgggta cattcggcga cacgggtctc cgccctcttc
     4021 tggtcgatgt atgcccggga caacccctcg aggccggctt ccttctcctt tcctgccctg
     4081 gcaatactct gttcggcaag gcggattgtt gcctttgcct cctcgagatc tgcaatcagg
     4141 cgaagatact ccgcaccgct cttctggtta atctgggaat ctatctcttc gagatccttt
     4201 tttaagtagg ctatctcgtt ctcctcgagg ctcctgtcag agtgaatcct ctcgagagcg
     4261 atgcgttcgt cttctatgac cctcgagagt gcagcgaggt cgcgttcgcg ggcatgcagt
     4321 gttgcggcaa cccgcattcc ttcgagacgc tgcagggtct cctgccactg gcggtaaagc
     4381 agtgcctgct ccctctccct tgccagttcc tcgagtctct gggagagctc gcggagcagg
     4441 agctcttccc tctcgattcg ctccctcacg acctcgagtt cggaaagtgc ctgttccttc
     4501 ttctggtcaa actcggctac cccggcaatt tcgtcgataa tcttcctgcg ctcgaagtca
     4561 ctcatctcga tgatccgggt gatatccccc tgcatgacca cgttataccc gtgaggcttg
     4621 atgccatgac gggcgaggag atcattgacc tctgactgct tgcttaagcg tccgttgagg
     4681 tagatgtagc tgtaataccc ggtcgggctc cgcttgatac gcctccggat cttcgtcccg
     4741 tccgagaaag taagagttac ttccgcgctg ttcctgccag agttgagatt gatcaggtca
     4801 gtcagttttt ctgccctgag cgtccgggaa gttgaaaggg caaggacaaa gagtattgca
     4861 tcgatgatat tgctcttacc cgatccattt gggcccgaaa tgacagagaa accctcgtaa
     4921 aaagggattt tggtcttttt tatgaatgac ttgaaattat caatctcgag ttcggtgatg
     4981 tgcaaggatc agtgccccgt tatcgcttct ccgctggttc accctcttca tcctcggcaa
     5041 cgatgaggtc gctcttcttc ccggaaccct gcacgttctg ctttttcttt gaaaaccctg
     5101 ccgatgcaat gatgtaatca ctatttttcc ttttttcagg cttgagtgtg ccgtccggct
     5161 gcattatcat gtccatcttt tccggttcgg actggggagc cggttgtgca gtgctctggg
     5221 ccggtcgctg catctgtgtc tgggggcggg tctttgtctg catgatgatc gggccctggc
     5281 cctgccctcc gggagcgggc ttggtcattc tcatctctgc ccttgccctc tcctcgctga
     5341 ccttcgacag cttcatggca accgacttga gatcaaggag ttcctctgtg agacccttga
     5401 ccagggcatc gatctccctt actttctttt ccagggcagc tacccgctca tcgaggggtg
     5461 actggcccag atccttgtcc tttattattt ccatgtcctt ctcctcgggg ctggtcctct
     5521 cctttcaacc tgttcgggga ctatgaccgg tatcgcggag agtactcatt gtctatcatg
     5581 aattattcac ctataataat tatgctgcgc gtgattgcgc atttgaggct tttttccaga
     5641 attttgcacc atcgtatccc ctgatctgcc cgccccctgt tttcggcccg gatgatcgcc
     5701 cggtcatcac ggcgcacccg ttcccggatt ccggatacca atccccggac tggaccggtt
     5761 tttttcatga aggcgaaaat gtatttcctc attggaacca accattctct acatgtctta
     5821 tctggccagt accgatccgg agatcgcgga tatcatcagg aaagagatgg aaagacagcg
     5881 cgatggcctc gagctgatcg cgtcagagaa cgttgtcagc agggcagtac tcgaggccat
     5941 gggctcgata atgaccaata agtatgcaga gggttacccg ggtaagaggt attacggggg
     6001 ctgcgaattc catgacatgg ccgagaacct cgcccgggac cggctcagga agctcttcgg
     6061 agccgagcat gcaaatgtcc agccccactc cggaacccag gcgaacatgg cagtttactt
     6121 tgccaccatg aaacttggcg atctcatgct gtcgatgaag ctctcgcagg gggggcatct
     6181 ctcccacgga tctcctgtca gcttcaccgg ccagttctac cgggttgccc agtacggggt
     6241 cgatccgaaa accgaggtcc tcgactacgg tgttgtcgag gagatcgcca ggaaggaacg
     6301 cccgtccatg atcgtatgcg gggccagcgc atacccccgg actatcgact tccgtgcgtt
     6361 tcaggagatc gctgacagcg tcgatgcctt ctgcatggca gatatcgccc acattgcagg
     6421 gctcgtggca accgggctcc accccacgtc ggtgggtgtg accgacttca cgacgacgac
     6481 aacccacaaa actctccgcg gtccccgcgg aggtgccatc atgtgtggga aggagaatgc
     6541 tgcaatcatt gacaaggcag tattcccggg gatgcagggt ggacccctca tgcacacgat
     6601 tgctgcaaag gccgtctgtt ttggggaagc tctccggccg tcgttcaggg aatacaacaa
     6661 acagattatc aggaacgcaa aagtccttgc agagtccctc atggaccatg acctccggct
     6721 cgtctcgggt ggaaccgaca accatctcat gctcatcgac ctgaccgatc gtggtatcac
     6781 gggccttgaa gccgagcagg cgctcggccg ggcgcacatc acggtgaaca agaacaccat
     6841 tcccaacgaa cagcggagtc ccttcatcac gagcggtctc cgggtgggaa caccggcagt
     6901 aacaagcagg ggcatgaaag aaggggaaat gcgccagatc ggtgagtgga tcgggactat
     6961 tctcaaggac atccataacg agcaggccat caggacgata ggggaagagg ttaagtccat
     7021 ggccgcaaag ttccccctgt acccggattg acatgattct cgacggaaag aggatatcag
     7081 aggaacgcct cgcgaaactg aaagaagaaa tcaggaattc gggcctcttt ccctcgcttg
     7141 ccactgttat tgtgggtgat gatcccgcct cccgcatgta cgtgcgcatg aagcaccgtg
     7201 catgcgaggc tgcagggatc aggtcggttg gagtcgagct cccctcatcc gcaagcacga
     7261 aggatgtgct cggcagtatc gaaaatctca acagcgaccc cggcgtcaac ggtatccttg
     7321 tccagctccc cctcccttcg catatcgata cgccgcggat cgtcgagtcc gtcgaccccc
     7381 gaaaggatgt cgacgggttt catccctata acatgggctg cctcttcctt ggcactcctg
     7441 tcttttcacc ctgcacgccg gcaggcatca tgaccttgct gtcggcttac ggcgtggaac
     7501 ccggggggat gcatgctgtt gttctcggga ggagtatcga ggtcgggcgc cccatggcag
     7561 cgctcctcct caacgcacac gccacagtca ccatctgcca cagcaggacc cgcgatctcc
     7621 cctcaataac tcaaaaagcc gatatactcg ttgtagccgt cggaaaaccg aaatttatag
     7681 gtccccagat ggtcagggaa ggcgcaatcg tcgtcgatgt cgggacgaac agggtcgaag
     7741 gtatcctgtg cggtgacgtg gacttcgaga gagtcaggga cgtggctggt gctatcaccc
     7801 cggtccccgg cggagtcggc ccgatgacga ttgcaactct catggaaaat acattcctcg
     7861 ctgcgaggat ccaggcatgt accgatgcac ggtaaagggg ctttctatcg gagggggagc
     7921 gcccgtccgg atcatggggg tgatcaactg cagcccggaa tctttctatt ccgggtcata
     7981 tacacctgcg ggaaacgtcc attcgcgtgc gtgcacattc gtcgaacagg gtgctgacat
     8041 catcgatatc ggggcgcgga gcactgctcc cggtgcacca cccctcgatc gtcagaagga
     8101 gattgcacgg atgaagatgg ccctgacatc actggaagga tcagggattc gcatctcggt
     8161 cgacacgatg gacagggaag tcctcgaggt gtgccttggg tacgatattg ccctcgtcaa
     8221 cgatatctcc gggctcctcg accctctcta tgcatcacgc gtcagcgagt ccgggctccc
     8281 cgcccttctc atggcgtcga tcaaggcacc gggagatccc acctctcttg acgaggtgca
     8341 ccgggccatc gcgatggtcg agacacgggc acatgccgcg gggcttgcag agttcatcct
     8401 cgatccgggg gtcggactct ggactccgga aagatccccg gccctcgact gggagatatg
     8461 ctgcaatttc gaggaattca ccatgtataa ccggccgctc cttgctgcta tttcgcgaaa
     8521 gactttcctt ggggtgattg gggacaggcc ccctgaagga aggcttccgg cttccctcgc
     8581 catgaccgcc ctcctcgtta cccggggtgc agatattgtc aggacacacg acgtggccga
     8641 gacgcatgat gcgatccgtg ttgccgaaag gttcaggcgt ggttcatgac ggtatcgtac
     8701 acggtgtacg ggatccggac ccccctgatt acgcggggag cagatcttgc ggggatcctg
     8761 attgatgcag taacaggaac cggggctgaa gagttccgga acggcgatgt tctggtcgtt
     8821 gcagagacag cagtctcgac cgcggaaggc tcggtcatcc cactcgaagg aattgaaccc
     8881 gacgaagaat ccatccgcct ctcccgacag tattcccttg atccccgtct tgtccagtgc
     8941 attcgggaag agagcgacga gatcgtggga ggtatcccgg gttttttact ctgcatgaag
     9001 catgggacgc tcctcccgaa cgccggtatc gatgaatcga atgcaccgcc cgggtgcgtc
     9061 tctccccttc ccagggaccc tgacggatct gctgcccgtc tcatgcacga gatcaggaga
     9121 cggacaggtg cccgggtcgg ggtaatcatc gccgacagca ggacccaccc catgcgcgtc
     9181 gggtgcagtg gcgtggcaat cgggtgtgca gggataaccc cggttatcga cgcccgcggg
     9241 agacgcgatc tcttcggaaa ggaactccat gtcacgaggc aggcccttgc cgacaatatc
     9301 gcctccgcag ccgagatcgt gatgggggaa gcagacgagt ccactccgtg tgccctcatc
     9361 agggggcttg acattcccgt cacagacaca tgcgggatag agacgatcga cgcttcagaa
     9421 tgcctcttca tgggactttt aagggaaaaa gaccggtaat tatcccggaa aacggaacag
     9481 aaaaatcatt tttcccgttt gggaaaacgg tctgaccatg ccttcctgac tgcctgaaga
     9541 cctgttaaaa acaggccggg tgccagaaaa aaggatttga acaatggaac gagggagaga
     9601 tcagatctct ttttttctct ctccacaatc cggggaagaa gaggtagtag aggttttatc
     9661 ctggtaaaaa tcgccttccg cgtgaaactc gtcagacctg ccgggcggga gatcttctcg
     9721 tgactcctac cctacccttc tcgacggaga gttcaaaacc gtgatccacg aggaactgtc
     9781 tgctcatccc ctctccgtgg atgagcagtt caacaaggtc ctccttttcg tcaacatccg
     9841 tgtgcaggcg gaaggtatcc acgacttcgc atgaaagccc ccgttcttct gcgatccggc
     9901 gatgcttgag gaaacttgcg ccgtaatagt caaccctgaa ggagttcccg cgggtaaggt
     9961 aaatggcatt tgttccgcct ccccgtccgg gaacgactgc aatgtcgcgt gaactcgtca
    10021 caaccctccc gatcgaggcg gcatcggcaa gggggaggtc tgccatgatg atgaggaccg
    10081 ggccgtccgt cactgacagt atctcgttga gtgtctcgtt taatccgtgc gggacaacct
    10141 ccaccgggca ccgcgggaat gcaaacaggg ccgtggacac gacccgggga gaacatcccg
    10201 ctctgcagac tgcatccaca acgtcgcaga gcatcgcccg ggcgaatgct tccctctctt
    10261 cgagggaaag gacgcaggaa aggcgcgtct tgggattccc gggtttgaag gggattattg
    10321 cggggacacc catacctgtc tcttttttca tttggtcgcg gatctgaaat accccttggt
    10381 ccagtccccc gcgccggtag tgcgccggct ccctgtatca catctggacc attaatgaga
    10441 tcgcaacgct cacgtaccac cattgcagcc atggtagtcc ggatcatcac cttctcaagg
    10501 aacatctttt tgcccctcac gaccgtctgc cacaacaggt gcgggtactg ctcgttccgg
    10561 actcctgtcc gggaagggtg tgtgctcccg ccgggaacaa tccttgagac agtgcgccag
    10621 ggtgcaatcc tcggctgtac cgaggcactc tttaccttcg gtgaacgtcc cggtctcgaa
    10681 cccggattca atacccacct ggcacgttac ggatacaggg atatccttga ctactgcttc
    10741 cacatggcag aaaaaacgat agaactcggt cttcttcctc acaccaatgc cggggtactg
    10801 acgtacgagg agatgaaacg tcttgcagag gtgaatgcga gcatgggcct catgctcgag
    10861 acgacagcac ggataaaggc ccatgaaaac tccccgggca aggatccggc cgtccggatc
    10921 gagatgatag agaatgccgg gcgcctccgc atccccttta ccaccggtat cctccttggt
    10981 atcggagaga ctgtcaggga tcgcgaggag tctctcactg tcatccggga catccaccgc
    11041 cggtacggcc acattcagga agtcattatc cagaacttct gtcccaaaga ggggaccccc
    11101 atggcacgcc atgctcccgt ggacagcggg gagatgtgcg gggccatccg catggcacgg
    11161 gaaatcctcc ccccggacat tgccatccag gctcccccga acctcgcgga cgtcgcatca
    11221 cttgtcccct gcggtatcga tgaccttggt ggaatatcgc cgctcaccgt tgactatgtc
    11281 aacccggagc accagtggcc ccagatcgaa gaattgcaac gccagcttgg aaattgcagg
    11341 cttgtggaac gcctctgcat ttatccccgg ttcatcgaga aaggatggta ctcaccccga
    11401 ctcaaacccc ttattaaccg actccaccaa caagtacagg aaaggagcaa gatccgtgaa
    11461 gaagggtgag gttctctaca agggtaaggc aaagtcactt taccggacag gagaccccgg
    11521 tgttctcctc gtcgagttcc gcgatgatat cactgcattc gatggacaga aaaaggatgt
    11581 tctctcctca aaaggccggt taaacgcgca ggtctcggca tttctcttcc ggctcctcga
    11641 gagaaatggt atagcgacgc attttatcga tatgcctgac gaatcccaca tgctggtgaa
    11701 ggcactggac atgatcccac tcgaggtcat cgtgagaaac attgccgcgg gatccctggt
    11761 ccggcagtac cccttcaggg aggggactgt cctcgaaccc cctgtcatcg tcatcgacta
    11821 caaggacgat tcccgccatg acccgatgct caacgacgac ctcatcatcg ccctcgggat
    11881 actgacaccg gatgatcttg cgatgataaa agagatggcg ctccgggtaa actctgttct
    11941 tcgcgaattc tttgcgtccc tcgggattac acttgtcgac ttcaagatcg agttcgggag
    12001 gactccggat ggaaaaatcc tcctcggcga cgagatcagc atggattcca tgcgcctgtg
    12061 ggatatgtcg accggaaaat cgctcgataa ggacgtttac cgcttctcga agggtgacgt
    12121 gatggaagca tacaaccgcg ttgcagagag agtctgcgcg gaagataagg aggtatgcaa
    12181 gtgacagatt ttcttgtccg gatcacgata tcgttaaaag agggggtcct cgaccccgaa
    12241 gcgagcctca tccagcgtgc cctggaaaac ctcggttttc ccaccggtga actgaagaca
    12301 tcccgccagt tcctggttcg cttccatgca gaaaatgctg acgatgcaag gaaacgggca
    12361 gaggccatgt gcgagcggct cctggccaac cccgtcatac acaggtacga gatagaggtc
    12421 atgaaatgag gtttgcagtg gtccagttcg gggggagcaa ctgcgaccgc gatgttgcct
    12481 atgtcttaaa cgacgtctgc ggcatcgata cggacctcgt atggtacaaa gagggactct
    12541 cccgtggata cgatgcagtc atcctgccgg ggggattttc ctacggtgac tacctgcgtg
    12601 cgggggctat cgctgcacgg acccgcatca tggatgacgt gcggcggata gccggcagga
    12661 atggccttgt ccttggcatc tgcaatggtg cccagattct cgcggagagc gggctcgtgc
    12721 ccggggtttt tacgataaac gcgtacccca agttcatctg caggcctgca tatctcaggg
    12781 tggagaaccc gaaaaacccc ttcacccttc tcttcgccgg gggagaggtc atcaggatcc
    12841 ccattgccca cagggagggg agatatattc ctccctccgc gggcaggacg ggtacactga
    12901 aggaagagtg tgtcgcattc cgtttctgtg atcccgcggg aaacataacg cacgaaagca
    12961 atcccaacgg ttcgttcgaa aacatcacgg gagtgctctc gtctggcgga aacgtgcttg
    13021 caatgatgcc tcatcccgag cgggcatcgg aggacatcct tggatcatcc gacgggaaac
    13081 ggatattcct ctccatggcc cggttcatcg aggagaactc atgaatgaag aaggattaaa
    13141 aaatgtccta tccgcggagg acgagaggga gatccttgcg tgggcccgtg aatatgcacg
    13201 tgtccaccat tggaccctca accctgacga aaagcgcctg atggtcgtga tccgcggcct
    13261 cgcccggaac aggaagaagt acggggagaa gtactgcccc tgccgcttgc gttcaggaga
    13321 ccctgaaaag gacagggata tcatatgccc ctgtgtcttt cacggggacg agattaaaga
    13381 acggggaagt tgtcactgcc agctctattt tgataccccg gataccggga agacaaacac
    13441 cccgtaaaaa ctcatttctc gtcctcgtat ccccccgggg cgaggacccg gtagatcgca
    13501 tagaacccaa tcacgatggc gaccaggtac gagagtatcg ccatgtagta gaccagttgc
    13561 gggagctgga tctgggactc cctgaggata aacgatgacc cgatgaccat cccggagacg
    13621 atcagtccta tcaggacctt gttgctcgtc cggtcgaggg acagctggag cctcctgata
    13681 tcggtatcga ctatgtcgat cctgatggtt cccgtcgaga gctgcttgag catctggttc
    13741 acgttccggg gcatgtccag gagaccatcc agcgtctcga tggtcgatcc ccttgcccgc
    13801 gtcgcaatct gctcgatgag ggactcgcgc ctgctgtact gggccatgaa cttttccgcc
    13861 tcttccctga aacgaaagtc ggggtcgagt gtgactccga cgtcaaggac catgacgatg
    13921 accttcagca tcagcatgag gttaacgggg acccggatcc ggtaatcgcg caggatcgtc
    13981 gtgaatgcat tcgtcatccc gctgaagttg aactggccga tcgttgttcc ctctgcttcc
    14041 agcagtgcac tgtatatttc gtcgcggaga tcctccctcg actgctccgg gatcctgaca
    14101 gagaggcctt cgagagcctt gaccatcagt ccggcatccc gggcgaccat gccgttgatg
    14161 agctggacga accagaacct cctttccggc cggatgaccc cgacgattcc aaaatcgaga
    14221 aaaacgagtt cgccgtcccc ggttacgaga aggttgccgg gatggggatc accatggaaa
    14281 aacccgtccc cgaatatctg ggtcatatag gcaataaagc cgttctgcgc aatcctttta
    14341 ggattaagcc cgaaatcgag gatcgcaggc acgttgtcaa ccctgacccc gtcgatatat
    14401 tccatgacaa gcagccttct ccggctgaac tcccagtaaa tctttgggac cttcacaccc
    14461 cggagagatt tcatgttgtt ccggagcatg tctgcattcg ttccatccct gatgaagtca
    14521 agttccttgc ggatctggtt ggcaaagtcc ttgacaagtc cccggggatt gtagaccttc
    14581 cactcgggaa aggcccgctc cgcacggcgc gcaaaagatt cgaggatgag gatgtccgtc
    14641 tcgataatgg actctattcc tggtctctgg actttcagga cgacgggcgt cccgtctttc
    14701 aggcgggccc tgtggacctg ggcaatcgat gcagatccaa ggggttcctc ctctatgccg
    14761 tcaaaaaagt cctcgtaccc gggcagttca tccctgatga ccgcacgaat ctcttcaaaa
    14821 ggcaggggtg cggtctggtc ctggagtttt tttaactcct ggatcagggg agggggcagg
    14881 atgtcctggc gggtactcat gatctggccg aacttgatga aggtcgggcc cagttcctcg
    14941 attgccatcc tcatgcgctg gtactcgttt gccgccgatt caacggggca ggtcctgcag
    15001 aaccggaacc tgtgcacacc gggaaacaac cgctggatga tgataccaaa cccgtacttg
    15061 aagagaacgt ctgcaatctg ccagtaacgc ctgaatttta agaccattct ctctcttccc
    15121 tgtgggcccc ttttcctgtt atccgtctcc ctagcggtgc gcaaagtacg cggttatccc
    15181 ctcgccggtc accgcgtcga tccgtgcaaa accgatacgc tcgaactgga cgacggcacc
    15241 tgcttctcct gcaacaagcc tctcgcacac tccttttatc gtccccccgg gtgtcaggag
    15301 ggttgcaggc acgcattcgt cgggaggaag ccactggatg atgggcgctt tcctcgcgcg
    15361 ggcttcggaa agcgattctc ctgcgtaccg gcacacgggt gactctcccc ccgtcaccac
    15421 ctcgacgttg aagaggtcct tgagccgcac catcccgcct tctccctgta actcgtcacg
    15481 gggaacgagg gcctttccgg taaaatggag ctcccttgtc cccttctccg ggttcgccgg
    15541 gtgcaggagg gcgtgcgctg tctggctggg tgcgccctct atcgtcacct cgacggggtc
    15601 gggaacgaag aagtacctgt tggcaaccgg atccacaacc gccctgttat gcgcatacag
    15661 gttttcccac gagaacgaga tgtctgtctc gccgattccg atttcaatga ctgcctccct
    15721 cacagcctgt ggagagattc cccgcctcgc tatcgcccgc aatgttccca ggcgaatgtc
    15781 gtcccagccg gagtattcac ccgaggttat ccctgccctc atctgggagg tcgagaggac
    15841 taccccttcg attcccatcc ttccatagtg acggtaaacg ggcggctccc acccgaagta
    15901 atcgaagatg tacttctgcc tccgcgtgtt tgcgatatga tccttgcccc gaattacgtg
    15961 ggtgatcccg aggaggtggt cgtcgacagc cactgaaaag ttcatgaggg gatatacgca
    16021 cgcctccttg cggggatgcg gcggactttt caggatacgg attgcaggaa aatcacgcat
    16081 cgcaggatcg ggatgggaca ggtccgtcct gacccgcagt gttgcctctc cctcaccata
    16141 cccgccttca agcatcctgg agaaagcatc gaggctctct tcaagagcca ttcctctgca
    16201 ggggcagggt ttttttgcca ttttgagttc cctgaagcgt tccgaatcgc aggtgcacac
    16261 gtaagccccg cccctctcga tgagcttttt ggcatattca tagtaaatat cgagcctgtc
    16321 actctggtag acaatgtcgc tgatggcaag gccaagccac tcggcgtcct ccctgaccat
    16381 ggtgtatgca gcaggatcga ccctcttggg gtcggtgtcc tcgatcctca ggatgtattt
    16441 tcccccgtag cgcctcacgt aagcgtcgtt gaggagggct gcacgggcat ggcccagatg
    16501 gagcggcccg ctgggattgg gggcaaacct catcaccacg cctccttccg ccttctcgag
    16561 tgcagggagg ccccggagat ggtcccgggg acgctcaagg tcttcggcca gtgccggatc
    16621 aagggtctgg aggagctctt cccggcgggc gtgggacagg gaagagacct cgctgatagc
    16681 ttccttcacg agaactgccg catccctggc cctttccctg aactcgggat gtttccccat
    16741 gaccatgccg ataactgtcc ccggtctcgg aacgcttttg tacctgacgg cattctggag
    16801 ggcaaagaga aacagggcct ttttcaaggg gtcttcccct gcggggcctt ccattttttc
    16861 agtaactccg cctgatgaag tgttcaccca tctgtaccag gagatctttc tcctcgctgt
    16921 ccgggagaat cgatatccgc tggatacctg tcctgacgag gtcttcggca gtctgccgga
    16981 cctctgcaat gacaccgagt tcctcgagct tcgcaactat cccgcggatc tgatcaggcg
    17041 atatatcgcc gcggtactgc gcgagatcaa ggcctttttc ccttgctttc aggtaaacga
    17101 gtgtcttttt tccttccctg atatcggatc cctggtcttt gccactcacc tcgggaggcg
    17161 caaggagatc gattaagtca tcctgtatct ggaatgccat ccctattccc tgcccgaagt
    17221 ggtagagggc ctcggtaaaa ctggggttgc cactcgcaag gatgctccct atcccggctg
    17281 cagctgcata cagcgccccg gtcttcttct cgaccatctt gaaatattca ccctcggata
    17341 catcgtcccg tttttcaaag gacatatcga ggtgctgacc ttcgcatatc tcgacacatg
    17401 tccttgcgag gagggatgtc gcgcgcacct ttgcgttgtc gggaacatcg gcaaggcata
    17461 tgaactcgaa tgccgtcgca aaaagcacat cgccggcaag aattgctgtt ggttcatccc
    17521 accgggtatg cactgtcgga accccgcgac gcaccgtgtc accgtccatg atgtcgtcat
    17581 ggatgagggt gaaactgtgt gtcagttcca gtgcaagggc cgcaggcatc acgtctgatg
    17641 agcttcccct gttgactgca tccgctgcaa gcaggagcag tgcagggcgc agcctctttc
    17701 ctcccgcgag cagcaggtgg gcacttgccc gcccgagatc gtcacatgca gacccaaaat
    17761 accggtaaat gagtgcatcc acctggtttg ccgtctgttc caggtactgt tttaattcca
    17821 tctcctcctc ctctcacctt tctcttttca atccagtttt acacggtgac cgtttgacag
    17881 gatgtgcaca tctttatgga gggtgtaccc cagtgactcc gagaactctg cataccctga
    17941 tgacatgcgg atgttaccat gtgcagggat gacatgctgc gggttcaaca tgtgaacgaa
    18001 ctcgtaatgg tcttccctgt aggcgtgtcc gctcacgtgg aggtccggga aaattcgtgc
    18061 acccgacata ttgaggcggg cttcaaccat gtacctctgg ccgatgttca tcgggttcgg
    18121 gatgatcttt gcactgaaga tgaccttgtc tcccttctcg atcttgtacg gtgtatcacc
    18181 gagtgctatc ctcgtcagga tggacccggg ttctccctgg tgccccgtta ttatcggaag
    18241 gaatttctcc ttgcctgcct tcatcatgcg cctgagagtg cggtcaaccg tcctcctgtt
    18301 cccaaacatg ctcatcgtct ggggaaacgc gaccagtttc atctgctcgg ccgtggacgc
    18361 gtacttctcc atggaacggc cgaggaggac tggctttctc ccgatctcgt gggcacattc
    18421 cgcaatggtc ttgacccggg caatgtgcga ggagaaggtc gagacaatga ttgctgactt
    18481 gtcgtcctcg tagctcgtaa tggtgtccct gacaatgtcc cttgctatcc tttcgctcgg
    18541 cgccctcccc cggttgtcaa tatacgtgca ttccacgatc aggccgagga ctccttcctt
    18601 tccgatctgg cgcaggcgtg caaagtcagg tggttccccg ataacggggg tcctgtccag
    18661 cttgtaatca caggcataca cgattgcccc cttcggcgta tgaaggacaa ccgttgcagt
    18721 atcgatgata ctgtgctgca tccgtatgaa ttcgagtgcc aggttctggg acagggtgta
    18781 tttctggccc gtcttgagtg caaaaagctt gttattgact ccgaatttct gttctccagc
    18841 gatttgctgg cgtatcagtt cgatagtata cggtgtcccg atgatcgggg cattgtaccg
    18901 gtgggcaagt ttcggaatgg ccccgatgtg gtccaggtgg ccatgggagc agatgattgc
    18961 ttttaccgtc ccctcgacgg aattcatcat cgtgtcgtcc ggtatcgcct tcatctggat
    19021 gaggtcgagg gaatgcatgt tttccacctc ggcctcctcg tggatcatca cctgatccag
    19081 gcgcagaccc atatcgaaaa tgactatctc ttttccgcag cggacggcgg tcatatttct
    19141 acccacttca tcgtacccgc caaccgcgat tacctcaata tccattcaat tatcctcctt
    19201 ttatctttcc aatcatttcc cgggtcttcc ccgtgatata cacccgggtc cgtttcatgt
    19261 ctctggtctt tttagccccg cacaggaaca tagcggtctg cagctccctg ttcagctcct
    19321 ctatccggga gaacagggcc tcctcgcttt ccattgccgg gcggagcagg ggaagtgcca
    19381 gtccacagag gtctgcaccg agagcgagtg cttttgccat gtcgagcccc gtcctgatgc
    19441 cgcccgttgc aatgacaggg ccgcccgtac ccacgacttc cacgaggctc actgcagtcg
    19501 gaattcccca ttcctgaaag agtgtgccaa gggcaaaaag gtcagcattt tttttcccgc
    19561 gggacttccc tgcccggaat gactcgatgg ccgcccacga ggtacctccc cagcccccgg
    19621 tgtcgattgc acgcactccc gctccccagc aggcctccgc cgtctccctg gatatcccgc
    19681 tcccggtctc cttgacaatg acggggacgg gactctccct gcagaacctg gcaagggcct
    19741 ctgtacaacc ggtggcgtca tggtcgcctt cgggctggat agcttcctga aggaagttga
    19801 ggtggatggc tatggcatcc gcaccgatca tgtcgatggc tctccctgcc caatccgggc
    19861 cgtgttcacg cagctgtaca atcccgaggt ttgcaacgag aaatgcgccg ggtgcttccc
    19921 tccggacgac ccggaagctc tcttcgagcg cgggatcttc gagggctgcc ctttgcgagc
    19981 ccacgcacat cccgataccg taccgctctg ccgcccgcgc gagcctgacg ttcacctcgg
    20041 tcgtgtcagg gtgtcctccc gtcattgcag caatgaagag aggcgaagag agcttccttc
    20101 cgaggaaccg ggtggagagg tcaatccggg agaggtcgca ttccgggagt gccgagtgaa
    20161 cgagcctgat gtctgaaaaa cccgaaaaac ccctctcgat ctcttcctct gcacaaatgc
    20221 gcaggtggtc caacttcctt ccggatgtga atcgtttctt atccattcgt attacttcct
    20281 gtaatccttg tcccgccgtg aggccttccg tccagaaaat ccccgagcct cgaaacatgg
    20341 aatatgtctg atgaaacacc gcatttcgca agtcccaaaa gctcctgtac ttttcctgcc
    20401 atgccccctg tgacgtcggt atgtcccgaa ctgcctgcag ataccatagg tccgctttcc
    20461 gggccgatcc tgctgatgac cgtgccgccg gaatcgagca caccggggac atccgttgcc
    20521 agtccgacgc gggtaaaggg tatccgctcc gccagaaacc gcacgatctg gtcgccggag
    20581 acgatggaga ctcctctcgc ctcgtccatg acaacatccc cgtggaggac gggagtgact
    20641 cccgcttcca taagggccag aagcggtctc tccccgagcg caacaagcct gccgtcatgg
    20701 gcaatggccg agccgagcgg atggatacca accgcttcaa tgcctgattc aaacaacgcg
    20761 ctgacgagaa ttgcattgag ggaacagaca gctgcatggg tgcgggcaat cccctctgca
    20821 aggtcagccc ccctttcccc gcctgccagg ccgtacctgt gtgcctccgg gtgtccgaaa
    20881 gacccggcac catggacgat gcagatatca ctcccatcac ggcgtgcgat ctctcctgca
    20941 atgctccgga tacgtccaag gtcagcaacg ccctcgcggc ccttgtccgt gagaatgctg
    21001 ccgcccagtt tgaggagaat cctttcaggc atccttctcc ttccggaccc cttccgtgtc
    21061 aagggtagtg atcaacgccc ttgcatcgca tgcctcgatg gcacccgcga ccctgctctt
    21121 gaggtgtttt ggacatatcg cgatcatgca gcctcctccc ccggctcctg tcagttttgc
    21181 cccatacgca cccgctgccc gcgcagcgag gatgagcctt gaaagaaccg ggtgacctgc
    21241 accgagtgct tcgaggagag cgtggttcgt atccatcagt ctcccgagtt catggttgtt
    21301 gttcaggttc cggatggcac agagagagac cgcaccgatg gcatcaagaa ccgggtcaca
    21361 gatatccggg ttcttcttcc tgaactcggc aaccttttcg accatctttg cagtgctgtg
    21421 ggaaaccaga gaattcccga tgacgagcgg gaggttctgc ggggggagac gtctccgctg
    21481 ggtcccggtt atcaggacga tcccgccgaa cgttgagacg ctcgtatcgg tcgggcttgc
    21541 ccttcccttc tggacctttt tttctatcct gtatgcaatc gccgcaatct cttccatcgt
    21601 gaggttcttc ccaaactcgt cgtttattgc cgcaagggtg gccactgtta cggctgccga
    21661 agacccgagc cccgaagagc tgggaagctg ggaattgacg tatacacttc ccctgactcc
    21721 catctcgtca aagcagctgt cgatgtacgg tgaacgtgca tggtgggccg ttttgctttt
    21781 cctcaccgtt acgaataccc ggggacggat ggccattgca actccgggtt ttccatagac
    21841 gacggcatgt tcaccaaaca gaaagacctt gcctggcgca ctccaggtcg ccaccctaca
    21901 tcaccgcgat ggccgcataa ccgaccactt ccggatcacc ggttacatcc ccactggtcg
    21961 cataacggag cagcttccct tccctggcac caagactcct gcatgcaagg cacatcgttg
    22021 ctattggtcc atacccgcag gcacttaccc gcctttctct tagccggcgg taaaaccctt
    22081 ccacatcgag tgtcaaaagc ggctcgatgg catagaggtc attttcgatt gctgtggcct
    22141 tcgggacata atgggaaaaa tcgctcgagg caacgatccg gacatctgac ctgccggatt
    22201 tccttatccc tgcaacgatt ttttccgcga gatcggcagc tgactgcaga tcctggtccc
    22261 ccatcaggac aggcacgatc cgtgcccggg ggaaccggta cttgatgaac gggatctgga
    22321 cttcaaggga gttttcctgg tactggtgtg agacctcgtc gacctcgacc ccgagtagag
    22381 acccaagctg cgaatcgtta tccacaagac cgagtggtgt ctcccagggg accagtgaaa
    22441 tacatgtaca gaaacccctg tggctggggc cgatcacgat gaaggtcccg gagaaagtgg
    22501 aggggatagc cccgtatgcg actgcggaaa cttctcccga gtaaggatag cccgcatggg
    22561 gggagactat tccccgtgca tcaaggccgg agtccttgtt cctgaagaac ttctccagga
    22621 gctgctcgag gtgatcgggg tccctcgggt agaacatacc cgcgaccgca cacttccggg
    22681 tcatcatcgg atctaccctc tcgtatccca cgtatattag atttcggtct caaaatcttc
    22741 aggggtgaga gatgtcgaga ttcccctcag ccggagcatc tccttcgtga gcaggtagta
    22801 gatcatcgag agtgcttttc tccccttgtt gttcgtagga ataacgaggt caacgaggct
    22861 ggtcatgtta ttggtgtcgc agagtgcaac aatcggaatc ccgctctgga ctgcctccct
    22921 gatcgcctgg gcgtcaccaa tgggatccgt gacaacgagg actgcgggtt cgatgtagcg
    22981 gtcaaggttc tggttcgtga gcatccccgg aatgaacctg cccgttactg ccatgccgcc
    23041 aatcgtttcg gcgaacttgc tggccggata ctggccgtac tggcgtgatg tgaccacgag
    23101 aatgtgcccc ggatcgaact ggttcaaaaa ttttgctgcc gtcttgatcc gttcgtccgt
    23161 ctcacggatg tccaggatat aaaggccatc tcccctcacg cggtagatga acctcatcat
    23221 gtccttgctc ttctgctggg tgccgatgtg gatacctgct gcaaggtact cttccacggg
    23281 taccaggggc tctttcaatt caatttccat ctctgtttct ggcatgctat cagttccttt
    23341 ctctctcatt gcgttctttg ttgcttacct ggaggacttt ggccatcctc ccgtccagta
    23401 ccatgcgcag gtgaaggctg cggttggccg acatgctctc tacttcctct tcactgtgat
    23461 aggtatgaca ttgtgctgga actcttcgag ggcaatttca agcggatcta tcttgtccgt
    23521 cttgatgaga agcggagccc ccattgatat ctggagggct ctcgccccga tgatccttgc
    23581 cctctcatac cgagtataag tctccttcat ataccctcag gaatgctttg atgtatgatg
    23641 aatggggtcg ctgagattcg aactcaggtc acagcgtccc gaacgccata ggatggtcca
    23701 ggctacccca cgacccctca ctgatacgga ttgagatcat caattatctc tttgtgggca
    23761 agcagcatcc tgcgacagca gtacctcacc atgccgaggt cgtcgaggat cttttttgga
    23821 tcctcgccag cctcctttct gcgcttgaat tcctcgtacg caggtgagat gaccttccca
    23881 caggtgaaac atcgcacggg tatcatgccg gtatgatctc ccattttatt tcagtatctc
    23941 aacgataaga cttttggaac ttcttcctcg caccccttcc gtggggcttt ttcggttctt
    24001 tctgccgcga atcgttcacg agcagcgtcc tgtcatacga gaggaagata tcctttatct
    24061 ttggatcgtt gtgccacttc aggagtccac gggcaagcgc cgtgcggatg gcctcggcct
    24121 ggcccatgat tccgcctccc cggacatcga tcgagacatc gacgccttcc agtgcagctg
    24181 gtgcgaggag aacgggctcg ctgaccttga gacggaccat ctcgttggga tagaggtcga
    24241 ggggtacgga gttgatccgg attatcccct ttcctgccct gacagtggcc cgtgcaattg
    24301 cagttttgcg ttttccactg gtattgatca cttttcccat tccatcaccc ttcctagaat
    24361 tttgccccaa ggaatgtact cacggcaccg atcgtcacga tcttcgggga gttcaacctg
    24421 ttcatgtggg cttcctcaag tgtctccatc gggcttccgg caaggtctga cggaacgccg
    24481 acgtagaccc tgatcctctt gaatgcctcc attcccgcag gtctcttgta gggaagcatg
    24541 ccgcgaatgg ttcgcctgac gatgtgatcc ggcctccggg gaaagaacgg tccgccttcg
    24601 cgtgaccccc tgctcctttt ctgcccgtac tgggaaagca cccgggccct gctccctgat
    24661 atgatagcct tttccgcgtt cacaatggca atgctctccc cgttgagggc gcgctttgcc
    24721 acgatgcttg ccatccttcc caggagaagt ccatcaccgt taatgattgt cgtcatcccg
    24781 ctcaccgcag aatcctgatt ttgctgcccc ggggattgtc cctgatcagc tcttcgatgg
    24841 tcatgcactg gccgtttgcc tcccggatct tcgtttctgc agactgggag aagttcaacg
    24901 cagcaatcct caccgatgtt tcgagcatgc cactccccag aactttcccg ggaacgacaa
    24961 tggtctcccc gtttccggca taacggttaa tcttgctgag gttgacctcg gcatagttcc
    25021 gggccggggc ttccagcctg cttgcaatat cgcgccagac caatgcctcg ttctgtcgcg
    25081 atgcatcctt caagagcgag atgaggttca gcaggcgtgg gtttgtcttc ttaatcgctc
    25141 tcttcttcat ctccggtcac tcccgataat tcactcactt gcgcacgcaa ctcatccgac
    25201 tggtctttca agtacttcag tgcccccgtg atgatgtctc ccacggggag agagccatca
    25261 ccttccacga cgaagataaa acgggacttc tccgacgtta tcgtgatcgc gggctcttct
    25321 ccgattcccg tgctcatgca cgctttttcg cagaggcggc agagagagca ttcctcgagc
    25381 cggttttcaa tcaccgttac cctgccgttc ctgacctcga ggatggagcg gggacactcg
    25441 tccacgcacc ggccacaccc gtcacaacgg ttgctgacat cgatgacggg gtaattcttg
    25501 aacccgcatg cggttgtcgg ctgccacttg gcatgcactc ttccgcagtt gaggactgcc
    25561 cgcgcctcga gaacgacctt ctgatccttt cccagtttta cgatggggat cgtgtcgacg
    25621 gccgggactg cgcgtgggtc ctgggggatg aggtcacgcg aatagaccat cccgggacct
    25681 tccacagaga gcgtgaaagc caccccgcac ctgtcgcatc cttctcctcc acaactgcac
    25741 ttgtcctggg gaacgtaaag tccgggttct gtttttatgg ggatgagccc cagcctgtgt
    25801 gccagcatct cgtcaaagag ggcacttgta ttgtcataga tccgcacgtc ctcgatggca
    25861 agggtcggga cttccccaat cattgccctg cggaatgcat ttgcaaaggc ctgtgagggt
    25921 cctgaaagac agaaccttgc ctgggaatcg tccatgcgca ggatctctat ctccatcaga
    25981 ctctccttcc tctccggcca cccttgggcc tgatcgagtc atgggggacc ggcgttacat
    26041 cctcgatccg cccgatgcgc atcccggccc gcgcgagagc cctgatcgca gcctgcgctc
    26101 ccggtcccgg actccgctgc tttcccctgc ccggtgccct gaccttcacg tggacgccga
    26161 cgatgccctt ctccatcgct gcctgggcca cgttcgtcgc catctgcatg gctgcatagg
    26221 gagaactctc gttcctgtcc tgcttgacga ccattccgcc gctgctcttg cagaccgtct
    26281 ctgccccgga aagatccgtg atggtgatga tggtgttatt gaacgaggcg aatatgtggg
    26341 caatacccca cttctccttc tcacctgcca tcgtgattac ctccctgccc gggcaatacg
    26401 ggccctctca gcatggtcgg gatttgccac gggtgaccgt ctgtagtacc cgatctcgct
    26461 ctcctcggcc cttgaaacac ggtaacccgg gatgctgacg cgcctgccgg cgatggcaat
    26521 gtgaccatgg gtgatcatct gcctcgcctg cttgggtgaa cgggcaagac ccttgcggta
    26581 gacgagtgtc tgcaggcgcc tctccagctg gttctccact ttcagcgaca ggacatcgtc
    26641 gatacctgca tcaggaccga gcagccccat gcgctgcagg tgttcgatta agtcgctctt
    26701 ctttgcctca aagagggtct ggtcctttcc ggtggacatg agtgccagga ggtcacgtgc
    26761 agccctccgg aaccgcctca ggtgactcgc cgccttccac acctcccgct tgttacgaag
    26821 cccgtactcg atcatgagcc tgttctcttc ctcgatccgg gacttctcaa agggtctctt
    26881 cggcgtctgg tactgcttgt ggtttttacc gggatatccc atgtacaatc acctgcgtct
    26941 actccttctt cctcttgacg cccacagtcg cccctgtccg tcccgtggac tttgtcctct
    27001 gacccctcac tttctgcccg gtctcgtggc ggattccctt gtaactgcgg atctttcgca
    27061 tgaggttgat atcctcatcg agcgttgtaa ccacttccgt gccgaaaagg tgtctgggtt
    27121 ctcccgtgta gatgtctttg ggacggttga ccatccatgc gggaactttt ttctcgtacg
    27181 tctccacgac ttcccgcagc ttgtcgacgt ctgcttcgga gagtttcccc atcagttcgc
    27241 gggggttaac acctgccatc tgggctatga cgagcgcggt atgtcttccc acgcccttga
    27301 ttcctgtgag cgccgtcgtg acgggttttg tcccgtccag gtcggtgttg ctgatcctga
    27361 cgaaataccg tatgtcttct tcctgagcca ttcaatccct ctttcctgtg agaatccccc
    27421 atttttcagc gctgagggag ggatttgaac cctcgagtcc caaggggaca caggtttagc
    27481 aaacctgcgc cataccgggc ttggctacct caacagagaa tctcgcatcg ttcagacact
    27541 cgcagcacca ggtggtgcca ctccatgaat ggtgctaatt aattggtctg caggttataa
    27601 aaatcctttc tcccctcttc gggatattcc ccttgtcttt gggaggtata cctctggtca
    27661 tccccgggta atcgggacag ggtatctgtt ctgacgcggg acattgcaat cctcctttac
    27721 catctgtagc gagtgccctt tacgggtaac ggcggggtgt atctctttct gtcttctcat
    27781 gccgggatgt acactgaaaa gaaggtgtga ttcagtcaat gccctggcgc aggatctttt
    27841 ccctcctggc cggggcatgg gcaacacggc ggacgtcgtc tgcgatgagc gcggatacaa
    27901 cgagagggag ggcgattgtt gcatccacat ggacctggac atgcctggta tgggccgact
    27961 ccttgcccca gctgatggct tcctcgaacg tgcacccgga cagccccccg aagtgggggg
    28021 aatctgtcgt atactgtatc gcgtagtcat gtccgccgag atctttcgcg tggatggagc
    28081 caatcacctg ggtctgctgg atgaaattct tgggtacgcc accacccacg tagataactc
    28141 ccgttctttt cacttcctcc acgagggacg tgacttcgtc cgtatccgca acctggtcga
    28201 tatctatctg gacgcccctc cggcgcgcaa tgagagcacc gatcccgata gaggagtcgc
    28261 acagtgcggg aacaaatacc ggaatcccct cccgcacgca ggtcgaaagg aatgattccc
    28321 ggccgggaac cgctttcatc agccactcac caaagagtct caggaattcc cgcgaagaac
    28381 cccggaatgg tgctattttt tcagcgaagt ttgcaatacc cctgtcaacc cacctgaagt
    28441 cctcctcgta tgcaaaaata tcatagatac ggtcgatgcc cttctcatag agttcgctgt
    28501 cactgacgtg gtaatgtccc aggtaatggc agacccccag gtgctcgcac acgtcatgga
    28561 atatatttgc ccctgtcgag acgacgacgt cgatgtagtg ccggcgggcg agctcgatga
    28621 ggactttctg catgcctgcc ggtaacatcg cgcccgagag accgaagaaa atggtacatt
    28681 ccgggtctga aaccatctcc ttccatacct cgacagattc tcccagtttc cttccctgga
    28741 acccgcagcg tgccatcctc cggagtaact ctgccacgtt gtccgatggc acgactggtt
    28801 ccgtggttct catcttctct ctctttttga cttccagggc acgaccaagg actgcatctg
    28861 ctcccccgac ttttccaaga agatcgtcgt tcttctctgc cattgattag tagtggtccg
    28921 gcaatcgata agtaacatgc gcacatttca ccggggaagg cgggcaggca gcacgtggtg
    28981 cataataatt tccgcaggtc cgctggttcg gttcgaatga cccggatagg ggcacgacag
    29041 gaaagagtgg aacgtccaca caaggggaat ataaaaaaag caaaacggga aaaaatggat
    29101 ggagggaggc cgaccttatg gtcagagagc ccggatgagt gatgaccttg tgaccatccc
    29161 gacaatcctg tccccattta caaccggtat ggagctgata ccccgcgaga gcatgaggtc
    29221 tgccgcctcg tcgattgttg cattcatgcc gagagttatg acaggggttg tcatgatatc
    29281 cttgacaagg agattgcgga tgcggtggtc ctggtgcctg tcctcgacga tctcccggaa
    29341 cttgcgcatc gcgactgcca catccgtctc ggtcacaatt ccaatgaggc ggccgttttc
    29401 tgttacaaga cacctgtgaa ggttgtcgtc gatcattctc ctgcgccagt gcacgaccct
    29461 ttcatcctgg tcaatggtgc acgccggctc caggacgtcc tcgagctttc cctgggggcg
    29521 catgacacgc aggatgtcgc cggcagtgac ctgcccgacc agtctgtggt cctcgtcata
    29581 gaccacgacg agcttgtatg tctggaggag cgggatgacg acgtcgaggt cctggtccgg
    29641 atacaccgtt gtgaagtcct cctcgacggt acttgccacg tggatagagg tcggggagat
    29701 cgacgagttt ctctttgtgc cgagtttttc cgcaacgctc tggcgggaca cggtaccgac
    29761 caccgagtcg tggttgacaa cgatgagggg gtcaacaccc tcgtcaagca tcctgtccag
    29821 ggcctcggtg atgggtgcgg atttcgatat cgtcaccggc cgggacatga tatcctttac
    29881 cagtatctct tcagtcattt ggccacttcc cgaataatat catctctttt caggattccc
    29941 ctgatctcgt cgtcttccac gacaacgagg ctgttaatgc ggtgcgactg catcatctgg
    30001 accgcctcct tgagtgttgc actcccggca atggttatca caggccggga catgaggtct
    30061 tctgcaattg cagcagcctc cataacatac cggaactgtt tccttccacc ggactcgccg
    30121 cggcggagca tcaccacgtc ctttatggga atatcccgct tttcatcctc gtaaaggaag
    30181 aatgcaaggt tgctctcggt gatgatcccg gccagtgtgc catcattatt gaccacgatg
    30241 accttatcat tcctctcctt catcaggtcg atgacatggt caagagagtg gtaccggctg
    30301 acggtgatcg catcttccat cacgtccgcc acggtcatgt cgagattccg tactgcctcc
    30361 gacctcatca ggtccgactt ggtcacgata cctgccactt ctgtcccgtt taagacgggc
    30421 agaccactga tatcgtgctc gatcatgaga cccgctgcct tccgggtagg ggtttccgga
    30481 gatatcgtga taggatcccg cgtcatgaga aggctgaccg gtatgttgtc aatcggccgc
    30541 cgcctccata cgggttcgct ctgccgaagg cggtacccga tgtccttctt tgtaaggatg
    30601 cccccgaggt ttccttcctc tatgacaggg agacgggaga tcctgtgttt gagcatgatc
    30661 ttccgtgcat gggcgatgtt ctcacccggg ccgacaacgt agacgggtga gctcatgatg
    30721 tcctttgcct gcatggtggc tcactctcct gaaaatgccc tgacaaggtc gaactcggtt
    30781 acgagaccga tgagccttgt tccctcgatg acggggaggg caccgacacc cctcttcacc
    30841 atctcggcag cggcctcgtt cgcactcttt tcgggcgaga tggtgtagag ctttccggat
    30901 acgagtgtcc tgatggggag ggccatcacc tcggcgatgt ctccgctctc catctggtca
    30961 aagactttcc tgctcccgag gtatttcacg atatccgtgg tcgtcacgat accgtagagg
    31021 acatcaccgg ataccacggg cagtctccgg aacctgtggc gggtcatctc acgagtcacc
    31081 cagccgatgg gacagtcagg ctctgtcacg cggagtgacg tgctcatgat atcctcgacg
    31141 gttgacgaga ccctctctcc cgcaagtacc gtcatgacat ccctttcggt aacgatccct
    31201 gccagtgcag atgaatcgtc gacgatgggg atccctcctg tcatcttctc ctttataatc
    31261 ccgatggcgt catcgaggga tgccgagtca ggcagggtcg ttacgttcgt cgtcatgatg
    31321 gtccggatgc tctcgttgac tgcggcgatc aggttcccct tatgcttgac ctggacgagg
    31381 ttgaacttgt cacccccacc aaggaaatta atgatgtctc cggacgtgac gattccgcga
    31441 agcttttttg atccggcatc aacgacagga agcctgcgga acccgcattc tgtcatcgtg
    31501 ctgactgccc cgaggatggt catcgtctgc gggacagaaa caacatccct cgtggcaatc
    31561 gccattatct ctcccttttg ttccacgatc ctggacttga actcaaccgg gccgcggtcc
    31621 agttttccag gcattttgag gagcttgtcc ccctgcttgt aagacttatc tccgtggtgt
    31681 gccatgttaa aaaccccctt cacacattca tacccgatga aaaattccgg gtctttctca
    31741 tgcttcctgc gggactgctt tcaggacatc atgccgatcg agtattcctg caagacggtc
    31801 accgtcaagt acagggaggc ggctgatgtc atgcttcacc atgatccctg cagcctgctg
    31861 cagttcatct ccgggagaga ccgtgatgac gggcgtcgtc atcacattct ctaccttcgt
    31921 ctttgccggg ccttcccgcg cgggtcgcca tctgccatcg cggaggaggt cgctgcgtga
    31981 gattatccct acaaggcgcc tcttcttcat gacggggatc gctgaatatc cgctctccac
    32041 gatgaggttg tatattttct gcacggtgtc ttctgcatcg cacgagatga catctcttga
    32101 catgtaatcc gccactttcc catctagaga atgtcgtgat gctatgacag ggaagatatc
    32161 cggcaggcgc acacccccga tgaccctctc ctgctcatcg acaaccggca cactgtcagt
    32221 gccattcatc cggatgagtt ttacaacctt ttcgattgaa tcatccggag ttgcaggtgt
    32281 aacctccttc acgaagccct cgatggtgac atcagacctt gttgcgggga cgcggagcac
    32341 cccggttatg tccacgtaac caaggagcct gcctttcccg tcatgaacgt acgcctcccg
    32401 gatgaaagca tcgcgaagca cggacctaac tttcgtcacc ttctcgtcgt gcttaaaatg
    32461 cggcacctcg accatgaaat cgcgggcttt cttcattgta acagttcctc ctcacggcat
    32521 gagggacaca acaggttgtt gtcgatcctc cggaggtcat ccgacatctg gccgcaccgg
    32581 ctgcacaggc ctacctcgac ctcctcgaga cggttgattt caacgaggtc tgccatcaac
    32641 tcgttgatct ccgtcgatac cgtgagaata tcgcgaactg tgacaatccc aataaccctg
    32701 ttctcgtcgt caaccacggg gagtcgccgg acccggtgct tgatcatcat gtgtgccgca
    32761 tcaccgacag acttgtcggc atttatggta atgagtgggg tgctcataat gtcatgagca
    32821 aggactgacc ccggtttaat gtccttggcc acgaccttgc agttgatgtc ctcctcggtg
    32881 acaataccga tagggagatt gtttggacca aggactatgc agcttcccac ctcgtcccgg
    32941 cacatgagca tggccgcacg ggcaactgtg ccctcgtatc cgatagtggt ggggttgcgc
    33001 cgcatgacct cgcgtacggg cacacgggtg ttgaagtgga tcttcccgga tgatttgctc
    33061 attcgatcac ctccatggtg ctgactggta tagggtttgt tgcagttacc attactgcaa
    33121 gtgaaatcta aatacctttc tcccttcccc tcaaaaatgg tataataaac ctaataacca
    33181 ccttccccaa taggaataag tgaacaggca cgcggccgga gatgttattc tctcaatccc
    33241 gcgggccgga gtctgaggtg caccatgaat attctggtcc agaccaagaa acgcatatcg
    33301 agatttcttt ccgcattttt cagaaaaaaa agggcaagga taggtattta cggtcctccc
    33361 aatgcaggca agacgacgct tgccaaccgg atcgcaaagg actggaccgg cgaggacgtg
    33421 ggactcgtca gcgagatacc gcacgaaacc cgcagggctg cacggaaggc ggatatcagc
    33481 atcatggggt cgaacgggag caatattacc atcgacatcg tggatacgcc cggtgtcact
    33541 accaagatag attaccggga cttccttgag tatggcatgg acaaggagac tgccgtgagc
    33601 agggcaagag aggcaacaga aggggtcgcg gaagccatgc actggcttag ggaagacatc
    33661 gacggggtga tctacatgct cgatgccaca gaagacccct tcatgcaggt caatatcatg
    33721 atgataggca ttatcgagag caggaagctg ccggtcatca tcgtggcaaa caagatagac
    33781 ctccccgacg ctatgccgca gcgcatcagg agcgcttttc cccagcatcc cgttgtccct
    33841 gtctcgtgca ccgaggggaa gaacattgag gacctgtatg aaaagatggt ggagtatttc
    33901 gggtaggagg ggtgcatgat gcagggagta cagatagacc tgatatcttc ggaaaaactt
    33961 gaaaaactga catcgatgga gaagattcac ctcatcctcg accatgtacg ccagggcact
    34021 atcatcatcc tcgaaaaagg tctctccccc gatgaacaga gtaccttgat cgagatgacc
    34081 atgcgggaga tacttcccga cgggttcaac ggtatcgaga tcgagacgta cccttcaagg
    34141 gagcagagcc cgggatttct ccagaaactc cttggtaagg caacccctga atcacggctg
    34201 acggttattg gtccggcaaa ccagctccgg ctcatccgga aggaaaaaga tatcctcagt
    34261 gcctgggtct cgaccaggtg atcccatgcc tcacaagtgt gtccgttgcg ggaaagaata
    34321 ccggacaaac gagtgcgaga tcctgaaagg ttgccgggaa tgcgggggga aaaaatttgt
    34381 tttcattccg caggtcgaaa gggagccaga aaaggagcct gttactcctg tcacccctgc
    34441 ggcatcgcca gaaacacagg ataaggaaaa agagcctgat actgctcctg atgtccccct
    34501 cctcggaact gaccgtctcg agagtatcag gatcgtggca cccgggacat acgagttgaa
    34561 tatagaaaag cttgcaactt cggacgaacg tgtcgtgggc atcgggaagg gagaggggag
    34621 ttacctcgtt gacctcctct cgatggtccg ccccaggcga aaaaaggcaa aaaagtagca
    34681 atccaccctt tattaattga tattgtccac gctgtatccc ttgctgacga ggagctcctt
    34741 gaccctttcc ttgtggtttc cctggagttc gatggacgtc cccttgaccg ttccaccgca
    34801 ggcaagtctc cccttcatgt acttggaaag gtcctcgagg tcgatatcgg tcggattcaa
    34861 cccttctata accgttactt cctttccata gcgtctccgg tctactttca cactgattct
    34921 ttgctgttcc tttgcgactt cctcgcagat acagagttct ttaggcagtc cgcacgtcgg
    34981 acatatccca ccattcatta caagtacctt tcagttctct ttatatattt gttggcatgg
    35041 gtaaaaaccc tccattggca tgataacagt gccatcagag gatgaaatgg cggtctcatg
    35101 caacaagtgt gtccaccctg catgcgtcac agccccgtga tatcacctgg tctttcctgc
    35161 tccggtaccg gtaaacggtg atacccttgc accccagttc ccgcgcataa aggaatatgc
    35221 cggagatgtc gccaggtgat gcctccgtcg ggaggttcac ggtctttgaa actgcattat
    35281 cgacgtattt ctggaaggtg gcctgtatcc tgacgtggaa ccggggatcg atctccccgg
    35341 cattcctgaa cagttccctg atatcgcggg aaacgggcag atcctggacc gaccctttcc
    35401 tctcagcttc cagaaggagt tcttttccgt ttgggagacc gaggaagtgc tttcgaagtt
    35461 ccgggtggac gatcgcaaaa cgcttcccgt cgataaccct ctcgcttgca caggcaaaaa
    35521 gaggctcgat accgctgctc gtgcacgcga tgatgtggag ggaaccggtt ggtgcgatgg
    35581 tggtcaccgt ggcgttgcgc atggaccctg aataaatact cctgtctatt gccgggaacg
    35641 atcccttctc ctcgccgagg gtccgggatg cagcgtggga ctcctcctgt atgaaacgca
    35701 tcagattctc cccaagagtg agggcctctt ttgactggta cgggacctcc aggcgtatga
    35761 gcatgtctgc aaatcccatt actccgagtc caatcttccg tgtctggagg gtgcactccc
    35821 ggataatggg gaggggaaac cgattgacat cgataaccgc atcgaggaat tcaacggcaa
    35881 gccagacgca ctccctgagg gaatcccaat caatatcccc ttttttcagg aaacgggaca
    35941 ggttgaggct cccgaggtta cagctctccc atggaaggag aggttgttca ccgcaggggt
    36001 tcgtggcctc gatctccccc agtgccggga cagggttctt ctcgttgatg cgatcgagga
    36061 acagcacacc gggatcaccg cacccccacg ctgccatgga gagtgcatcg aataagtccc
    36121 gtggttctat ctccctccac acctctccgt cccgcggatt tacgagcggg taagcgtgac
    36181 cctgcccgag acatgaaaag aactccgcgt caaaacccac agagaggttg aaattctgga
    36241 gtcctccggt ttccttcgaa tgaatgaatt ccaggatatc agggtggtga ctcgaaagaa
    36301 cccccatgtt cgcgcctctc ctcttcccac cctggcggag tgcattggtg gcctcgtcaa
    36361 aaaccctgat aaaagagata ggcccgctcg caacccctgc actgcctcca accatgtccc
    36421 ctttcggacg cacgcgtgaa aaagaaaaac ccgttcctcc tccgctcttg tgaataagag
    36481 ccatgtaccg gagtaccgag aagatctgct ctatcgagtc ctccacgggc aggacgaaac
    36541 atgccgaaag ctggccgcat tgtgtccccg cattcatgag ggtcggggaa ttcgggagga
    36601 acttcagttc agacatgatc cccgcgaaaa gatcggcctt gcttgtcccg accgcctttg
    36661 caaccctccg gaacaggtct tccggtgttt caccgggcag gagataccgg ctcgccagga
    36721 gagcctccgc gggtttacac aactccatca aggagactga gtgattgcac tttatttaaa
    36781 atcatgtaaa tgtatgatca catgtccctg atggttctcg ggacctcgtc ccatgcaggc
    36841 aagagcacgg ttgttgctgc catctgccgg gtcctgagca accgcaatat cagcgtcgca
    36901 cctttcaagt cccagaacat gagcctcaat tcttatgtca cgcgggacgg gtccgagata
    36961 gggatcgccc aggcaatcca ggctaaagct gcccgtctgg aacccgtggc ggagatgaac
    37021 cccatcctgc tcaaacccaa aggcgacgca gtctcgcagg tgattctcct gggaaaaccc
    37081 tataaagacg tccctgcaca ggaatactac agggagaccg atttccttct ctcaaaggca
    37141 ctcctcgcag cccgtgcact cgaggagaaa tttggtcaca tcgtcgtcga gggggcgggg
    37201 ggtgccgcgg aagtcaacct gtattcccgt gacatcgcaa atatcctgat tgcacgtgcc
    37261 ctccgttacc cgatcattct tgttgcggat atcgagaggg ggggcgtctt tgcgcaggtc
    37321 tatggtacgg tctctctcct tccccctgat attgctcccc tggtctgtgg catcatcatc
    37381 aacaagttcc ggggtgaccc cgggattttt gcatccggaa aggagatcat cgaggagctg
    37441 acgggagtgc cggtcatcgg gatcctcccc cacatggaga tcggtctgcc cagtgaggat
    37501 tcgctctcaa tcggagacaa aaagtcgcgc tccttccctg tccgggtcgg gatcatcagg
    37561 ctcccccata tttccaactt taccgatttc gaggctctcg aaaagtgcgt tgcagtggac
    37621 tatgtccccc tgggatcttc cttgtccgga tacgactgca tcatcattcc aggtacaaag
    37681 aacacggtga gtgatctcat ggaactgtgg cagtccggca cggccgagga gatccgaaaa
    37741 actgccatgg agggaaagcc ggtcataggg atttgtgggg gattccagat actcggcagg
    37801 gagattatcg attcgggggt tgagtcccgc gccggggttt tcccgggact cggtctcctc
    37861 ggtgtcgtga cacgttttga ccggtacatg aagaagaccg aacaggttac cctccgggca
    37921 cggcccgttg gtcccattct gggaacgatg gggactgttt cggggtacga gatccacatg
    37981 gggattacct ccaacgaagg cgaggaggag gccttcgagg gggagggagc tgtcagcagt
    38041 tcgggtcttg tgtttgggac ttacctgcac gggctctttt caaatcctcc tgccgtggat
    38101 gcactctgca ggtacctgta cgagaaaaag ggactgtcct acagggactg gaaagataca
    38161 tccgatccct acgatgatct ggcagacgct ttcatgcagc acgtcaggat ggatattatt
    38221 tactcctttt tccaatgatt ctccggagaa ccggtctttg gatgatttca ccggaagtga
    38281 cctatggcga tggtatttca gggaggagga ctaacttttc atccagagtg agaaggggac
    38341 gttaccatgc ctatcaggct ctcgatcacg attgactccg aaacaatcga ccaggttgac
    38401 aagtttgcca aggaacaggg attcgaccgg aaccgggcaa tactggagtg catccgtgcc
    38461 gggatacaga aagtgaatgc aggtgaacag gttaatattt cacagaccac ccgcctcgag
    38521 gactataagg agatcagggc tatcctcaac aatatcgatg cgacattaaa aaacctcgtc
    38581 gaagagatac gcgtcatgca ccacacaatc gaggcagagt ggttaaaaga gaacaggact
    38641 gttccctacc agagcaggaa atggtacgaa ttctggaaga cttaaaaaag gattaaagct
    38701 catcccccct ttttagccca gaatattcat catgctgcgg taaccctccc cctggagatc
    38761 gccgcatttt accgcttcca cgaggctgag atcaacctct tccgcgtccc tgtggcgcag
    38821 gcagtacacc agtgccggag atttcttgta ctggcccccg atcctgaaat agcgtgaatg
    38881 cacgcagaac cggcaatgct ctaccggttc tttccgtccg ggaaggcagt cgacctttcc
    38941 ggccctgacc tcgagaaccc tgtatttttc accgctcatg accactcagc ctcccttctt
    39001 ttcccccgga accctctccc tatgaataat tcagccggtg cccgcgaacg ggtgtcagag
    39061 ccgggccacc cgttgaccgc gatcatattt tcagcctgat acccccggtg aataattccc
    39121 ggagcgctgc ttcgagttca tggattcgtt ccggaatctc cttttccatc actcttatcc
    39181 cttcccggat agtcacgatc tctgttcgta tcttttccct gtcattttca atatctctga
    39241 gagccttctc cacctgcgcg gctcttttta cttccgggtg ggaatggata aactcctctt
    39301 ttttccgaag ataaccttcc gcctcttttc gcctgtatac aagggatacg agagcggggc
    39361 atatcctgtc aggattggaa aagaggttta tttcttcctg gttcttgagc tggatgtcac
    39421 ctgagctgat cattgacgtg acaaggggca gtacattcct gaccttttca accgaaccct
    39481 cgtcaatgtt ttctccttcc tgtgagatga tgtcgataac cctctttatc tccttctctc
    39541 caccacccct cttctggaga atcttttccg cctttgcaaa gacatggaca agggttgacg
    39601 tcgtgccatg gatctccctc ccgatccctg ccaccctgcc ggtgaattcc tctttatgtc
    39661 ttaccgcatc ctgcaatgct ccatccatac cggcgcggcg gtcacagtct tccttttccc
    39721 tcgcaagtcc ttcctgtctg atgcccagat ctttttccct ggcctcaagg atggaaagtc
    39781 tctcccttgc ctccgcaagc gccgcctgtt tctcccggat ggagataaaa gactcgcgcg
    39841 cccgggaaaa agaccggttg cgcctcttgt cctcggcaat caggggggtc atctcattga
    39901 cctggtgacc gagttcatcg ataaggaccc gtacctcttt catctgatcg ggaaatgccg
    39961 ttcccaggta cctcccggga cctgcaaggg ccttgacaca ccccttgagc gtctctgtcg
    40021 ccacctggta aaatgcggac gggtcaggag gtgcctgccg ggcaagggat gtcgtgatgg
    40081 ccttttcgaa ctgcgggaga gaattgcgcg tgatcttctc gagtttcggg tgatatacgg
    40141 aatcccgctc gctccctgca agggtggttg cacgaacgag gagagcggaa cacacctcgg
    40201 tgaacttttc acggggctga tccatcctct tctggagctc ctccctccag gaatgctctt
    40261 cttccccgat gataacagga atttcttcaa gggatatttc cctgggcggg acggtttgcc
    40321 ttgatgcgaa caggtctctg acctttttta acatataaag ccctcacagg caacggccat
    40381 cgccatcatc cctggctatc tgccgtatcc tcgcgacacc gtctatttca cggatcacgt
    40441 cggcaactgc cggcggtaca aggctctccc actcctctcc tgcgatgatc cgcctcctga
    40501 tctcggtccc actgtgggag gccctctcgt acatggacgg ggactcaacg gcaattccct
    40561 cttccccgaa gagacggacc acgagggggt tgctcgagaa cacgatatcg aagcggggtg
    40621 ccatcgaccg cacgtgcgca acccagaggg cgttcctgtg gaggtcttcg atgggaatca
    40681 catagaccgg gtttccaatg gtaccaagag cccttgttat catcagcagc ctctcccctg
    40741 ctgtgaaggg gttcgacggt tcgtgggaga gctgggcact cccgatcccg atgatgatct
    40801 cgtcgaccct gcgggcaatc tcctcgagga tgtgctggtg gccgttatgg tacggctgaa
    40861 accttccgat atacagtccc cttatcatct gtcccccacc atgtttgcaa tccgggcagc
    40921 aaatgctcct gcaacaaacc cggcatcgat gttcaccacc gcgatcaccg cgcaggactg
    40981 gagcatgctc gcaagggctg cctggccacc tcccatgtag ccatatcccg tgctcaccgg
    41041 gacgccaatg acggggcggt cgatgaggcc cgcaacaatg gcggggagcg tcccctccct
    41101 tcctgccgcg accacgaaga catgggcatc caggcatttc ctgattgcgg ggaagagacg
    41161 gtgaataccg gcgacgccga catcatacgc tgtcctcacc gtgcacccca tctcctctgc
    41221 aatgacgcgg gcctcctctg cgacccgcaa atccgatgta cctgcactga tgacagcaac
    41281 aatccctttt cccggcacaa tgggagatcc ccgggatagc actcccattg cagccttctc
    41341 gtgccacgtg aacgataccc ccatctccct gcacgcctcc ctgatggccc tggcatgatc
    41401 cggtgacatc cgggatatga ttgtcctggg agatacctgg actgctttcc ttgcgatctc
    41461 cacgatctcg actggcgcct tgccctctgc aaggataacc tcgggtatcc cgcaccgggc
    41521 tgccctcccc aggtcaagcc gtgccagatc ctccacctct tcgatccgca gcccctcgat
    41581 ttcagcagct gcttcttcga gcgtgaggcg cccatccgaa aaaccggtca gcacttccct
    41641 gagcctgcgg ttcggaacca tgatgtgata attaagatat gggccccggt ataataagtg
    41701 atgtaacagc catgagctac ctggtatacg ttgccgcatt cggttgcggc gtggtttttt
    41761 tcctgtggtt ccgtgacatg cgcatatttg cgcggactgc cctccccggt ttcaggaagg
    41821 ctgcataccg cggtgtcctg tacagcgccc tttccctcct tggttttttc ttcacgtaca
    41881 cgtcaggtcc tgcatttcca accgagctca tcggccttgg gatcatcctt gccgccctct
    41941 acctgcaggg cagggtggaa cgggagaggg tctttgccgg gagtgactgg tgggaccgcc
    42001 tcctgggcaa agcaccgcgt tcaacgaaac accgcacgca ggaggggtga tatttcccat
    42061 gctccagaga ccaagaggta cacgtgattt tctccctgct gaaatggaac agcggcgcag
    42121 cgttgagaac gcgatgcgca ggatagccca tacatggggt tacagggaag tctgtacccc
    42181 gacattcgaa gaactggaac tcttcactct ccggtctggt gagggaataa ttgaggagat
    42241 gtatgtcttc gaggacaagg ggggaaggaa actcgccctc cggcccgagg tcactgcatc
    42301 cgtgctccgt gcgtacgtga acgtgggaaa aaccctcgca aaaccacttc gctggtacta
    42361 ttttgctgac tgtttccggt acgagagacc ccagaagggg cgttacaggc agttctggca
    42421 gttcggagtt gaactgatcg ggcaggatac cccccttgca gaggcagagg tgatcatgct
    42481 cgcacaggat ctcctctctg ccagcggtat tacattcaca ctccatgtag gacacctcgg
    42541 gttcatgcgg gcactcctcg gaggactggc accggaggac cagaaaaagg tcaggatact
    42601 cctcgataag aagaattatg acggtctgtc cgccttcctt tcctcccggg gggagagcgg
    42661 gctttctgac aggctgacgg cactcgtcga atgcagaaag ctcgatgatg cccttgcaat
    42721 cacgggtgac atgccgggga aagagaggat tcgcgaactt ttctcgattc tggaccaggc
    42781 aggtgttccc tataccctca acccgggtat tgcccgtggc cttgactact acacgggtat
    42841 ggtctttgag gcctttgccg aaaacctggg ggcagaaaac caggtcgccg gaggggggac
    42901 ttaccgactg gcccacctct tcgggggaga ggataccccc tcgtgcggtt ttgccattgg
    42961 atttgacagg gtaatggtgg caaggggtga catcccgggg acacctgcgg tccgggtcgg
    43021 tattgcacat acacctgatg cccgcgactg ggctttgcat gtcgcagcag cgttccgcag
    43081 tgcaggcatc ctcacggaga gtgacctttc cggaaagaac ctcagccagc agattgcctc
    43141 tatctcccgg aatgcagact tcgccctgat tatcggccgc cgcgaacagg agaaaggatc
    43201 cgtgaccctc aaggaccttc gctccgggac ccagaaggag ttgtcccttg cacaggcaat
    43261 cgccgaggtg aatggcgatg actcttgccg atgaactggc aagacaacag aggagtatca
    43321 gtgtcgcaga gtttttcgag aagaacaagc accttctcgg tttcgactct cccaccaggg
    43381 gaatcatcac aacgatcaag gaggcagtcg acaatgcact tgatgcgtgc gaggaggcag
    43441 gggtcctccc ggacatctat gtccgggtga cgcggacagg cccggacacc tttcggataa
    43501 gcgtcgagga caacggtccg ggaatcgtcc cgggccaggt tcccttcgtg tttggaaaac
    43561 ttctctatgg ctcgaggttt caccagatac gtcaaagcag gggacagcag gggataggta
    43621 tcagtgcagc cgttctctat gcacaactga caacggggct tcccacgctc gtgatatcac
    43681 gcacgggtcc ggaggaagca gcgttcaggt tcctcatcca gatagatatc cagacgaacg
    43741 aaccggtcat catccggaag gagaagatcg attgggacag gacacacggc acactcgtcc
    43801 aggtcgagtt ccggagcacg atcgccgcga aaaagaagct cctcgagtac ctcaaataca
    43861 cctccatcgt caacccccac gccaggataa cggtcgagat ggagggggag acgactctct
    43921 tcgaacgggt cagtgacgaa gccatcgcgt gtccaaagac catcatgcct cacccgcacg
    43981 ggatagagat tggccagctg atgcggatga tcgccgggtc cagggccgct tgtggagaat
    44041 tcctcgtaac cagcttctcc cgcgtcggaa agaaaacggc ccatgagata tgcagggcag
    44101 cagggatatc tccggatacc ccggtctcgt ctctttcccc tgcggaacag aaaaaacttc
    44161 tctctgcaat gcagaacgcg aaagtccctg caccaacgac ccaggtctgc ctttccccca
    44221 tcggggaaga tctgatcgtt cgatccctcg aaaaggagtt ccagatggac ttcgtaaaag
    44281 caagaacacg gcccgggtca gtctattcag gtcacccgtt tctcgtcgag gctgccattg
    44341 gctacggagg taaactgccc gccgatggaa acgcaataat cctccgcttt gcgaaccgtg
    44401 tcccccttat gtaccagcag ggggcctgtg caatcacggg gtgtattgcg gggatcacct
    44461 ggaaaaatta caatgttgcg caggcaggtc ttcccaccgg ccccctcctc atcatggtcc
    44521 acgtcgcatc cacgaacgtg ccctttacga gcgagagcaa ggacgcaatc gcaggcatcc
    44581 ctgagattga acgcgaggtc accctcgttc tccaggaatt aggccgcgaa ctcaagacgt
    44641 atctctcgcg gagggacaaa agccggctcg ccgaggaccg ggcgagggcg gtctgtgcca
    44701 tcatcccgga tattgcatcg aaggttgcag agatcgtgga gcttcctgtt cctgacactt
    44761 cgctgatcga ggggaggctc atgcgcaggg tcgtcgtgaa aaagatgagc cggaacggac
    44821 atgtcacaat cgaggtcagg aaccatatgg cgacgacaaa tgtactttcc ctctatgaca
    44881 tctcgcgaaa cccagcggac gatgcacggc ccgcgccctc attcgcgaca gaactcgacg
    44941 gggagtacac acggatgtgg cagctcgaaa ttccaccggg tggtgtatgg acagcagaat
    45001 actcgggaac aggcgggggt accgttcagg tcagggggat tccgcctgaa aacatcgcgg
    45061 tagtggatct tgacgcagag tgagacgctc gaaaagaggg catacgagag gctgatggca
    45121 atagccatgc agtggtaccg gcagatggcc gaggggaaca tcccctccat cacgctgcca
    45181 acccggacga agcagaacat cgcctacgac gatgagtccg aagtgtggaa actgggtgac
    45241 cgcgagagcg tccggtcagc gcacacggcc aggagtgcgc tccacctcct caaaatgtcg
    45301 tacgtaatcg ggtttttaaa aacccagctt cgtgaaaacc gttcttcaac cctgagggag
    45361 ctgtattaca tctccgaggg ttggaaaaaa gcaaagttct cggcccagga cgagagcaac
    45421 tacctcatcg aagatctcga gatcctgaca gacctccagc gtgaagcttt ccacctgcgg
    45481 ccggaagagg atggcgcaac catattcggc cctctccggc tcaaggagat gacaagaagg
    45541 ggggagagga taatccactg cagggatgat gtaggcgagg cagggtacca gatcccctgt
    45601 aacgtggaga acgtggaact tctcgaccat gacgcgagtt gcgttatcgc aatcgaaaca
    45661 ggaggcatgt atgcgcggct catcgaaaac gggttcgacg aggaataccg tgccatcctc
    45721 gtgcacctga aagggcagcc cgcccgttca acccgccgca tgctccacag gttgtctgac
    45781 gagtttaacc ttcccgtcta cgtctttacc gatggtgacc cctggtctta ccggatttat
    45841 gccagtgttg cttacggggc aatcaagagc gcgcacatgt ccgaactcct cgcgaccccg
    45901 aaagcccagt tcatcggtgt ccagccaagc gatatcaggg attataacct tcctgcagat
    45961 gccctgacag aaaaagacat tgccgcgctc cagagcgagc ttacggatcc ccgtttcgga
    46021 tccagttact ggaaggagca gatccagctg caactggccc ttaacctcaa gtcagaacag
    46081 caggcgtttg cagcgcgggg tcttgacttc gtcacccgcg agtacctccc gcggcggctc
    46141 tcggagatgg ggctcgtcat ccgatcatga acctgaatat tatccatgag atcaggagca
    46201 tgatggcgga gtatttcaat cccgcagtga cccgtccctc acccatctga cctgccacga
    46261 ggccggagaa gattccctgg atcattgccg cgtgcgagaa gagccgtgta tagaagaata
    46321 aatcgatgtt tccgatgaac gaagcagcac cggcaccggc agactccgcg gcacttcccg
    46381 ccgtggccat cgtgctcaga aacgtgctca ccaggatgaa tatgacaaag acgaaaacga
    46441 ggaacgagat aagcacgata atgacgtaaa taagcatatt attgcgccgt tctgtgcgga
    46501 gggcgagtac ctcgtaagta tcccgcgccg ctgcccggag gacctcgctc acatcgcccc
    46561 cggccttgct cgcctttgcg atgaggtcga tgctcctgtc tgcaagaggt gtcccgaggc
    46621 gggtccggaa cctctggatt gcctctataa acgttgtatt ccaggacatc tcgttgtcga
    46681 ggcgccgaat gaacggtgtc agggtgctgt attccccctg ggcaacgaga tggatggcgt
    46741 ttgggagagt catcccactg tcgttcattc ctgcaaggtc gcggaaaaag ttggggagtg
    46801 cttcctcaag gttctttatc ctgcgattct cccggaaatc catcactgca accgggacta
    46861 tcgcaacgag gatggagaaa acaacgacat cgtccacgag agttgtcgag aagagcacac
    46921 ccatcccgta atccctgatt gcaagcgccg tgcccaggac aaaaacgatg attgaagcag
    46981 ggagggagac aataaggata ttgaggggtt tttcgaggag gactgcaaca gggtgcttga
    47041 tgacgcgcat cacccctgac cgctctgcac ggactttctc caatttcctg atgatctctt
    47101 cctgttcacg ggcaaacttc ccgatttctg ccggggaaag gtctatgcct gcaggcttct
    47161 tccttgagaa aagccccccg atacctgcag cttttccacc ggaatccgtg gcatgcatgg
    47221 aggggggaga cgggggaaag ggctgtttct ccttcttttc ctgtgcaggc gggactcccg
    47281 tttttccact ttctttgtct ggtttttccc tgcccggatc accgagtatc ctgtctttga
    47341 gtcccacctt cagccctccg gtgtcatgga actgatcagg atgacaaaca tcaggcttcc
    47401 gaagggaatc atcatgtaaa tgatgatgta gaggaatatg ggctgcgatg atttggagag
    47461 gatggacatg atggactgca ggatgatcaa aaagagaggg cctgcgacca tcgctgtgac
    47521 gtatgactcg gatatgagtc caagggtatc gaggaacaat ttctgtgact gcctgttctc
    47581 gagtgaatac tgttctgcct tggtccggaa gtactccgtc aggctgctcc ctgcagagat
    47641 gcatcccatc gccccctgga ggaactcctt catgcgcagg ctcggcgtcg ttgcggatat
    47701 cagccggagc gcatcgagaa ggtcacgccc gaagaggtcg atttccattg ccacgaaccg
    47761 ggcctcgact gcactctctc cgtacatcgg gctgtttcca agctgccgga agatctccgc
    47821 ggggggtata cccgcggtgg acatcgctgt aatgtaattg atggcatagg gaagcgttgc
    47881 atcgatattc ctgcgccggt ttccagcaac cacgctggga tacacgagga agatgacaaa
    47941 ggtaattccc ccgacaactg caaacgatat cacgatggca atgattgtcc cgatgatcag
    48001 gctgtattcc gagatgaaga gcatgaattc aggaacggca ccctggtact tgatcatgga
    48061 ggggatgttg aagatgaacg tgatgatgcc aaggacaacg gacgcgactg ccccggcaaa
    48121 aagggcactg aggtatgcag tagagaggta gacttcgaac gggactttca tcctcgcagt
    48181 gacgaggtca ctgcgcaatg cagcatactt atccctcttt ttccctgcaa gtgttccaaa
    48241 caaccgaaat gcaaaacgtt cccagctgtt catgtttctc catacagttc tgccctgacc
    48301 ttctccattg tccgtgcagg gtcacggaaa tactggatca ggatgttgct gacgtccctg
    48361 aaatgccgga tcttcttgag gcgcatccat tcgaggactt cctgacgcat cttgagctcc
    48421 tctctcatcc gctcctcgtc ccaaccccgg gactccatta tctcttcaag gacgtaggac
    48481 ttgcccgagt aggtaatctc gtccgttgca ggatgccagc ggaacacctc gttcgtgatc
    48541 agctcgtttg tcctcgggtc aatgtccagg atctcgatga tctgcttgtt ccggcggatc
    48601 ctctggcctc cgacacgggc ctgtacctgc acggagatga ggtcgagagc agagagcatg
    48661 ttcctcggga cgttcagggg agggttttca agacggtgga caatgcttgc aaccgaatcc
    48721 gcgtgcatcg tcgaatatgt cacgtgacct gtgctcatcg cctggaagag agtgagagct
    48781 tccttgcccc tcacctcccc gacaaggatg tattcgggtc tctgacggag cgctgcacgg
    48841 agaagctcgt acatgtcaat ctcgcccttt cccgacgcgt caaaagatgt ccgcgtaata
    48901 ctcggtatcc agttggggtg ggggagcttg agttcccgtg tatcctcgag ggtcacgatc
    48961 tttgcaagag gggggatgaa gagagagatc gcattgagag acgtggtctt gcccgatgca
    49021 gtcccgcctg caaagatgca tgacttaccg ctctcgacag cgagccagaa gaaggcgatt
    49081 gcaagcgggg agaaggtccg ccactcgatg aggtcggtcg gggtgatagg ttcatccttg
    49141 aatttcctga tggtgtaggt agaaccatgg gctgtcacct ccgatccaag agtcatctgg
    49201 atacgcgacc catcgctcat ggtggcatcg agcatgggct cggcaatgga gatatatttt
    49261 cccgaccgct gggcaagttt tatcacaaag gaatccagtt cttcggcgct cttgtacacc
    49321 aggttggtgc gcatggattc gtacctgtta tggaacacga aaaggttcgc attgacgcca
    49381 tcgcaggaga tatcctcgat gtacctgtca tgcatcaggg ggtctatcat cccgttaccg
    49441 aggaattcct tgtacattgc atacaggatc ttttccctct ggaccggtgt gagtgaaatg
    49501 ccataatcag caatgatatc atccgtcaca tcccgcaacg tcttttttgc gacttcctct
    49561 atgacgttct gggtgttgat atcaaggcgt tcgaaaatgc gttccttaat gtcgttgaag
    49621 agatcaagtt ccgcgggggt gagcttcggt tcgaggacct catacatgta ttcatgggtt
    49681 gcgttgtcgt atgttatcct gacataggca tagggttcgt taacagggta aatttcaatc
    49741 tcttcaaccc cgggccgcgg gcggaatttc aggtcgacaa gaggaccgtg tgtccgcatg
    49801 ttatattcga cagggacttt gcgaatgacg ttgagtggat tgagtttctt cagaagtgtt
    49861 ttagaacctg cttcggcctg aacctcggta gcggcgtcgg tgacagtcct gatactgcct
    49921 tcgagaaggt ctgatttctg gagatctttg ccctggccat cactcaccgt tcccttgaac
    49981 ttgaatatat cagtcttttc tgatattttg atttcatcga tctggaatgt tgcacccttg
    50041 ggaaggatga gtcctgaaat gtcatcgatg tcatcgacgg atacaattgc ctctgtttcc
    50101 tgctctttct cccttgattg ggtcaccttt ttagccggct tgaacgacgg ggaaggaaac
    50161 gcacgggcag gtttctcttt gccttcccct gcgctttcct cccctttatc ctgctgcatc
    50221 cgtgtgggcg gcgcagcctg ttcttggggt tttcgttcag gttcgatctc cggaatgctc
    50281 ctttccgcct gaaatgcggg gacaccgggc attttctcca tccggggcac aggagtccct
    50341 cccgtggttt cacctgtatc tggcaggggg gttactttcg ctgattgccg gacgggggcc
    50401 ttctcctttc ctggtgcgga tatccccagt ttctttacca ggagatcgag atcatctttc
    50461 ccgacgccgg taatctgccc ggatgttgca ctatcttctg tcttttttcc ctttcccggc
    50521 agttcctctt tcttcctcct gaataaagag ccgaatatac cgtctttttt tgaatctcct
    50581 gtcatcccaa tgacctttcc cagacccggt cgttccccct tgggcggatg tatacgaggt
    50641 gtttacgcgt tatacactat gaaacatttc tttgtggagg atggtgactg caagacgtat
    50701 cattccaagg tgcgctgtct tgtctgcaag gatacagagt gaaaggtccc cgtagggggc
    50761 aatcacgcag gttccctggt ttccctcgat gacaacgcag gcgggggacc cgagattcat
    50821 atccagggca acttttcctg cagtcctgat aaaatcctct gcaatggcag ccacatgttc
    50881 aaagtcccca tctcctgatg tctggaccgg gaatccctca aaaaaagcaa gtactgcatg
    50941 gaccccctgc aatgccatga accgggcaag caccccgtca tccagtcttg cacggggcac
    51001 attctttggc tttacggcct gcttgatgga tagccctctt tcaaagcaca tttcctctgc
    51061 aagtgccatc tcctcgggac cataccggta ctggatgaaa cggggctcga gtgatgaccc
    51121 ttccatgttc ttcaggaggt aggtaacggc ttcagatcca tggtattcat tttctttctc
    51181 gcgataacag gcagcgatga cttctccttc ctttgcgaga aagagacctg caccttttgt
    51241 ggtgaaaacc tctatttttc ctgaaaaagg taccttctct cctgatacag tatcaacgag
    51301 cggatcctcg acaacaccga ggtatgttcc ccttggaaat ttcatgcaat tcagagagcc
    51361 gcgacgagtc gatccttatt cttcttcaac tcgtaccgga tacgccccac gtttgcctca
    51421 tttcctgcaa ctatcgcgat gagctcatcc ggggaaaggg gggacatgat gatgggtccc
    51481 tggtccagtt cgacaagcat ctggcggagt tcccccttcc caagttcctt tcccatggct
    51541 tccgatgtcc caaggccggt tgaagccatt gcaccgaggg cgtcgatatc catctttcct
    51601 gaaactgcac tctcgatgac aaaaccatcg cggccaacca caactgcagc agagacccct
    51661 tcgatcttta aaaattcacc cagaatttgt ttaagcattc atgccacctt tccatcagac
    51721 tatctttctc gttatatata ataaaaaact ttggttatcc ctcctctcta tcctgcgact
    51781 ttccattcat ggttcaattt ttccaatcct tatcattctc ttaccaatag gattatctgg
    51841 aggagcgaac tcaattggta tgatgcaact accccgtggc atattccgct cgatcgaaaa
    51901 aggggaaaaa ctcggcgatt ttctcaaaaa actcaattca gaccagtttt ccggagtttg
    51961 ttccattgtc tgtgaaggcc ataccattga gattgtcctt gaaaaaggga ggttttcact
    52021 tgccagctgt gataatcttt ccggagatga tgctatcggg gtcattggcg gtctcatgga
    52081 gcggcctttc gatgcttcca tatcggacct tacccccgcc cagttaaaat tatcccgcga
    52141 gttcaatgaa gcgttcattg tcagaacctc ttttactgca gaaaaaagca ttcagaatcc
    52201 acaattcacc aaagatgaga gtattccagc tgctggtaaa atccctctcc aaaaaccgga
    52261 atataaaccg caaaccgtta ttcccgcacg acatcaaaga aaaccacaag atcaggatgc
    52321 attaaatgtt caggtcgcaa aatcagaaag gaattctatc ccaaaggata gtgagaggac
    52381 gcccgcgaca cgcaatgaag ctttattcga gacgggagag gaaaacatta attcgcctga
    52441 acaggggtat actcttgatg atcttgactt aaaagcactt gactccatgg atcttgatgt
    52501 catgtcaagg aagatccggg ataattgtaa acttatggtt gaacgcctcc acctcggtta
    52561 tctggttgtt gacgaggata aaaaagaaag tggatgaaaa atatggaagt aataaccttc
    52621 gatctctttc ttctcatcac ggggctgata ctggttggta tcatactttt cctttctctt
    52681 gtcagtgtca tttacactgt ccgccttgct tacaagatgg acacacttat gaaaatgatc
    52741 gacaccttcc gtcctgtttc aaaagttgat tattcaattc ccggcatcga aacgaaggtg
    52801 aaacgcgggg aacccgaaat aagtgtaaaa gaaaccgtct cagttccgga aaaaccaaag
    52861 ttcgatccgg cccgtgatgc tcctgacatc ccgtcaggaa tgcaccgtct ctgtgaaatc
    52921 tatgggatcg aatccctgac actctccact cctgacggcc tcgtggtcgc atcaacaggg
    52981 catccttctg ctggcgatga cgctgcccgg gtgagttatg catccgtgac ggggacccct
    53041 gtcagtgaag agggtatttc tgtatttcat acggattaca aggggaatgc cctggttggt
    53101 attatcaggg gaaacaggga aataccaaaa gatcttctcg gtgaattgaa aaaggacatc
    53161 aattcactcc tccagagatg gatttaggtg cattcttttc atgaagtctt cattagactt
    53221 atataaaaaa agaagaaaag tttcctccag ggagggatga atggtccggg tctttacttt
    53281 tgcgtcagga aaggggggta cgggaaaaac aaccgcaact gtcaacatcg gcacttgtct
    53341 tgcgcagttc ggcaagaata cgatcatcat ggatgccgac atcgggatgg cgaacctcgg
    53401 cctcgccctt ggactcgaag acgttccggt caccctccac gaagtactgg caggaaaagc
    53461 aaacgttcag gatgcaatct atgagggccc ggcaggtgtc aaggttgttc caagcggcat
    53521 atccctgcag ggtttccagc aggcaaaccc ggagcttctc aaggatgtct taaaagacct
    53581 cgtggaggtc tgtgattacc tcctgattga tgcacctgcc ggtatcagca gggacggcat
    53641 catacccctt gctgtcgcag acgatgttat cctgatcgtc aacccggaat tgtcctccat
    53701 cgtggatgcc ctcaaaacaa aaatattgac tgaagtcatc ggtggacatg ttttcggtgt
    53761 catcatcaac agggcgggaa tcgacaagtc cgaggtgatg gtccagaaga tggagaaggt
    53821 gctcggtgtc cgggtcattg gtacaatccc cgaggatccc aatatcagga aggcagcatc
    53881 agccaagaca cccgtagtca tcaagtaccc cggttcccct gcgtcagtgg ccatccggaa
    53941 cctggcgggt gaactcgccg gcatcccgat ggaacagagg gggggaaaat cccaggaaaa
    54001 gttcatcgaa cgtttttcaa aagtcctttt caggggtaaa aaatgacaat agaacaaatc
    54061 cttctcctct tggcatgcat tgtcattatc attctcctgg tcctgatttt tttcatgtac
    54121 gtgcggataa ggcaactcat ccgggatctg gaagtgctcc agtcaagact atcaatttca
    54181 gattcggaac tggatacact gatcaataac gttgaacgga tgataaagaa aattaaaata
    54241 taaatttcaa aaattatgat ggtctgttcc ggacctggaa gacgcaatgc tcgtctccct
    54301 ttgaccggca cttaatttct tttgcatccg ccttgatatt atatgccccc tccacgatac
    54361 ctgcaaggag acctgctgta cagaaacaaa cgtttttccc tgtgttcccg attgattcag
    54421 attccacggt atgctccagt gtgaatgttc ttgtcttttc tgcctcgttc cactcctttt
    54481 tgataatctt gaaccatccc atctgcgagt aaaatgtaaa ggccatgttg cagatagtat
    54541 ccggatttgt ctttttgagg acctcttcct tgtaagtgcc caggatctca tcttcgggag
    54601 tcccgacaaa caggatgccg atgatattat ccgcggaatt cctaatcggc tcataagcga
    54661 cgacatattt cctgccaacc acatctgcag tgccgtaata ggtctgtccc tttttgacta
    54721 cggcatcgta gacaacactg gaaatctctg ttccgaccgc ccgcttgcca tcggcgccaa
    54781 taacatttgt ggatacacgg atcgccttat ccccaatctt ctggaaaaca gtggccttgc
    54841 tgcccagttc cttttcgatg gaatcgacca cttcaaagtt attgttgact atgtggttgc
    54901 caaatgcaag ctgatcgccg gaaatggaag gaggcccgaa cgcaaggaaa cgtttccgaa
    54961 gttcgttgag atcctgatca agtttggtcc gggagagatc aaaggagata ctcatcttct
    55021 tgtagtgctc cacgttctct tttcccatgt ctttgtaagc acggtaattg accccgcttg
    55081 ccgaggcttc acccatggtc tttgtcaacg aactggtcat ggacgagaag atgaaccgtg
    55141 gcatcataac aaccggttca tccataagtg aaattctccc ctcaaggggc ttgtgttcga
    55201 tgaattcggt gattgctgaa tcgcccctga caactgcttc tgccttgaat ttccagcttg
    55261 gatggacctg atcagccacg aactcacaga aggggtctcc tttggcatgg cagcttcttt
    55321 caagacagaa ccagtttttt cccgtaatgg cagagagaat tccttctatc cagccctgat
    55381 ggataccgca tacgggcatg ttccagtcct tcagcacctc ggactcaaac gtctgcttgc
    55441 accgcatgac gatacgcttc tcggaagctt ccacgagctc gaacggagat ccccatccct
    55501 gctggtgttg catcgtgaag accagcatca ggaattcttc cggtttcagg ttcaggccaa
    55561 gttttttcag gagcttgttt agacccacgg atccatgtcc cacagagcgg aacagctttc
    55621 tcatggcctt atttgcgagt tttttcccaa ggtttgcttc atacatctcg tacagggctc
    55681 ttacgagaaa atttgggttg ctggcagtcc tgacaccaaa gcaggtcgtg actccctctg
    55741 ccgggttcat atgcatgtag gcagtgatgt ccttgctccc cttgaggata ttttcaaaat
    55801 cctctttttt cataataccg ttccttctat cctattttag tccctagtac ctaaatatta
    55861 tgctttttaa aagatgccgg gaagtgggat atcaggtgcc ggacacaccc ggaatggtcc
    55921 attctatcat ccgtggtgat gcctctctcc atggagagaa cagcagactt atttcacatt
    55981 ccctatatca agtgtcacgg gtttattgtt gagtccggga tggaattcga actcgtacat
    56041 ccgggtcgtg aggtcacggg aatggacaac acattcgtat ttcccataga gcagcctgaa
    56101 ggatactttt ccgtctgccc gtgtaaagtc attcccgatg acctgacctt ccttcctgat
    56161 ggagacccgg tgccctgcaa gtggtctccc gttatcgacg atgacgaccg agaatatccc
    56221 tgcacctccc tccctttccc ttttaacctc aggtatatcg accgggagga tgcgcctgag
    56281 tatctcctga tcaaagatgc gacacccaag aatcagtcgt tcgacgatct cgggcctgac
    56341 cggaaaaaga gtgaattgct cagttccctt catgagatat actgctttat tcccaaagag
    56401 ggcacccttg gaatcgtgca gcaccgcacc gttggggtca ccctcgagga aaaggaggta
    56461 aaaatccccc tgcttttcct ttgcatgccc tattccggaa aatgaatgtg ttcgtgcgaa
    56521 tgagagagca tgggtcaggc tcatgggtcc ttcaccggct gacccggata tgatggattc
    56581 aagaatttcc ctgcttgtca ggagatacca cctccttttc ctgatcgaac cccgataaga
    56641 accgcccgta accagggagg cagggatcat tcttcccaat tcccccccgc ggggagtctt
    56701 tgggggccat acatatgaac ctgtacaact catgatatat ctgtatccat gataattcct
    56761 ctggcnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    56821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnncggtc tggatatcct
    56881 acgggattcc tttcctcgtc ccgctgacgg caggagtcat atccgctctt ctcttcgggg
    56941 acatcctctt cttcctcatc aggtttattg caggtgtctg atatgcttca actgaactat
    57001 tcagacgggc tcatacccgt tatcgtgcag gacgcccgga cacgggatgt actgatgctt
    57061 gcctatgcaa acgaggaagc catttcgctc acgcgaaaga ccggttatgc ccattatttc
    57121 tcacggagca ggaaaaaaat atggaaaaaa ggcgaggaga gcgggcattt tcagcgtgtc
    57181 agcgggattc tcgttgactg cgacgaggat gctgtcctct acctcgtcga acagaccggt
    57241 gccgcctgcc atacgggata ctggtcgtgt ttcttccgga caattgatgg cgagatacgg
    57301 ggagagaagg tgttcgatcc cgggagggta tatgctaata aagaataggg acaagattgt
    57361 accggtgata ttttttgatc atcgtgccgg atacaagcgt ggtgatagac ggtcgtatca
    57421 cctccatgat acaagcggga gaatataagg gtgcaacaat agtcatacct gaagcagtgg
    57481 ttgcggagct ggaagcccag gcaaaccagg ggagagaaat agggttcctt ggacttacag
    57541 aactgcaggc actctgcagg cttgctgcgg agggcaccat cggtctcaaa ttcgtgggtg
    57601 tacgaccaac actcgaccag gtgaaactgg ccagtggcgg ggaaatagat gcactcatca
    57661 ggagtgcggc aatcgaacac ggtgcaaagt tcatcacgag cgatatcgtc caggccgagg
    57721 tagccaaggc caagggcctc gatgtcatat acctgcgccc gcaggtagaa gggtttgccc
    57781 cccttgcaat cgaccagttc ttcgatgaac acacgatggc cgtctatctc aaggagagag
    57841 tcccccccat ggccaagaag gggactatca gggagatgcg gcttgagaga atcagggatc
    57901 agcccatcac ggattacgaa ctgcgcaaca ttgcacagga agtcctcgaa cgtgcgaaac
    57961 gtcatcccga cgggttcatc gagcttgaaa agcgcggggt aacggttgtc cagatcgggt
    58021 cgatgaggat cgcgatcaca aggcggccct tctcggacgg catggagatc acggccgtcc
    58081 gtcccattgc cgacgtcaag ctcgaacagt tcaagaaagc ccagatcatc aagacgcgga
    58141 ttatcgggga ccgccgcggc cttctcgtcg caggtccgcc gggagccggg aagacaaccc
    58201 tagcccagag catcgcgaca taccttgcag agaacgggta tgtcgtcaag acgatggaag
    58261 ccccgcgtga actccaggtc cctgaccaca tcacgcagta cacaaccctt gatgggagca
    58321 tggagaacac tgccgaggtc ctcatgctgg tccgaccgga tttcgtcata tttgacgagg
    58381 ttcgcaagaa cgaagatttc cgtgtctttg ccgacatgcg gctcgcggga atcggcatga
    58441 tcggtgtcat ccacgcgatc ggggcccacg acgcactcca gcggttctca gaccgtgtcg
    58501 atttcggcgt tctgccgcag attatcaaca cgatcatctt cgtggacagg ggcgaaataa
    58561 ccaatatcta cgatatcggt ttcacgatca aggttcccga agggatgtcg agcgagatca
    58621 acttgaggcc ggtgacgacg gtatcggacc acgagaccgg ggagattgtc tttgaaatat
    58681 tcaagtacga tggcgagacg atcgtgatgc ctgtcatgag ccctgtaaca tccccggcgc
    58741 aggctctcaa ggccccgtcg atgccggcaa aggaagagaa cgcccagtgg aagatcctcg
    58801 aaaaggacat ccagagggag attgggaggt acaccgacgg ttacgtggat gtccacatgc
    58861 tctcggacac aaaagctgtc gtctacatag aggacaagga tgtccctgca gcaatcggaa
    58921 aagggggcaa gaacatcgcg gccattgtca acaaggtggg gatcggaata gacatcaggc
    58981 ccaggagcga acttgaaaaa acggctgctg cagcccctgt cgaggaagaa ctgcaccttg
    59041 gcggtggcgt gaagatccgg atggacaaga aacaacttgc catatcctgt ccggaacaga
    59101 gcggaaagat cgtcgatgtt ttcgcgggca aggagtacct tttcactgcc accgttagtg
    59161 acagcgggga gattcacctc gcgaaaaatt caacgattgc tcaggaactg attaagagat
    59221 acaatgacgg ggataccatc cggttaaggc cggtataggc aagaccattt tctttgcgca
    59281 cgagagggtg acagcacgtg aatctacctg attttgggca gctggaacgg gactgccttc
    59341 atgcatggga ccatgctttt gaagcgaacc cggctggaaa agaaaaattc tacctgacgg
    59401 tggcttatcc ctacccgagt ggtgcaatgc acgtcggcca cgggaggacc tacatcgtcc
    59461 ccgatgtgat cgcccggttc tggcgcatgc ggggaaggga ggtgctttac ccgatggctt
    59521 tccacgtcac gggagcaccg gtgataggga tctccaagag gatcgcgagg ggtgacgaaa
    59581 aggcaatccg cctttaccgg gacctctaca aggtgccacc cgagaccctg aaacagtttg
    59641 tggatcccct cacgatagtc cgccatttct ccgacgagta ccagagggtg atgagtgcct
    59701 gcgggctctc catcgactgg aggcgccgtt tcacaacagt cgacccgcag tacagcaagt
    59761 tcatcgagtg gcagtggaaa cacctccacg aaggcggcca tgtgaagaaa ggggcacacc
    59821 cagtccggtt ctgcccccag tgcgacaacc ctgtcggcga ccatgacctg ctcgagggtg
    59881 acaaggctga gatccagaag ttcgttctcg ttatgttcag atggaaagat gccttcatcc
    59941 cgacagcaac cctgcgcccg gagacgatat acggtgtcac caacctctgg gtaaacccgg
    60001 aagtcaccta cgtgcgggca cgcgtggacg gcgttccatg gatcgtgagc agggaagctg
    60061 cagagaagct gtcgttccag gaccacactg ttactgtcga ggacgagatt cccggttctt
    60121 cgctcgtcga tgaaaccgtt tcccaccgcc tctgtggcaa tgtcccgatt ctccctgcaa
    60181 aatttgtcga cccggggatg gcaacgggcc tcgttatgag tgttcccgca catgcgccat
    60241 tcgattacat tgccctccgt gacctccagt caaagggcct ctatgcacac atcaggccgg
    60301 tgagacttat cacggttccc ggttacggcg agttcccggc caaagatgca gtcgagaaag
    60361 ccggtatctc cagccaggac gatccacgga tggacgagat cacacagcag gtttactccg
    60421 cggagtttac atcgggtcgt ctcctgccgg aactgggagg gcagacggtg cgggaagcgc
    60481 gggagagcgt ggctgcactg ttgatcgaga acgattcttc ccggtacatg tacgagttcg
    60541 atacccggcc tgttgtctgc cgctgtggca atcaggtctt cgtcaagatc cttcacgatc
    60601 agtggttcct cgagtatagc gatcctgcat ggaaggccct ggtgagcagg caccttgagg
    60661 acatgacgct cgtccctccg gaagtgcggg cagaattcga gcggacggtc agctggttga
    60721 aggactgggc ctgcacgcgc cgggttggtc tcgggacacg tctgccatgg gatcccgact
    60781 ggctcattga accattgagc gattccacaa tctacatggc ttattacacg attgcccatc
    60841 acctgaagga attttcaccg gaggaactga cacccggtgt cttcgattac cttttcctgg
    60901 gaaaagaatg cccggatcat ccccgcaggg agaaacttgt ccagatgagg agagagttct
    60961 gctactggta tccctacgat taccggtttt cagccaagga cctcatctcc aatcacctca
    61021 ccttccagct cttccaccat gtggctatct ttccccggac ctgccttcca aggggaatgg
    61081 ttgtctttgg aatgggtctc ctcaacgggg caaagatgtc ctcttcgaaa ggcaacgtct
    61141 tcctcctcga ggatgcagtc agggagttcg gcgcagacac ggtccgcatg tttctcgtcg
    61201 gaagcgctga accctggcag gacttcgact ggaggaacga gctggtctcc tcaacgagga
    61261 agcagataga aaggttctac aataccatca tggagagccg tgatgcaccc cggaccatga
    61321 gcttggcaga cgcgtggctg gtatcccgcc tccagcagca catacaaaga acgactgaag
    61381 cgctcgaaag gttccagacc cggcaggcac tgcaggaagc attctttgcc atcgaatctg
    61441 acctgaagtg gtacaggagg cggctcgttc cgggcacgcc cggagggggt gctctccatg
    61501 agcttgcatc agtctggatg cgtctcatgg cgccagtcat ccctttcacg tgcgaaaaac
    61561 tctggaagga gtcagggggc aagggtctcg tgtcctatgc gcaatggccc gtgcccgaac
    61621 aggcaaaaat gaacggggac ctcgagctgg ccgaagagct gctgatgagg accatcgagg
    61681 atatcgagtc gattcaaaaa gtcctccagg ccaccccctc gtcgctttca ctatgcatag
    61741 cacctgcctg gaaacgtgac atattttcaa gggttgcccg ggcagatgac aggaatgcgg
    61801 ttatgcggga tatcatgaag gacgagcaag tccggaaaat gggaaaaacc gccgcagaaa
    61861 cgataaaaca gtgcaccagc ctcgtccacc gccttccccc cgcgatcgtg gaacagtacc
    61921 ttgccggaaa gctcgatgaa aaggccgttt tcctctcggc ccgggatttc atcgagaaag
    61981 aagcaggtgt cccggttacc atcgtggatg cggatgaatc agcgcacccc cgggcaaagc
    62041 tggcccttcc gctcaagccg gcaatcatct ttgagtaggg ggactctccc tactctgtct
    62101 ccacgctctt tgcccgcttt accctttcct ttgttgaata ccccgtaact gcgtcgagaa
    62161 atgcccggaa acgcttgttc gtatcgagta taacctcgtc tggtgcaccg atgtcagact
    62221 ccgtgtgcac cacgagtgtt ttgccgtcct ttcccggggc tgcatcaagc agcctgagcg
    62281 caccgtagga gagctggtaa tggtctccaa ccctgacggg ttccaccccg aaacagtccc
    62341 ggagcgacct ggcaattgaa ccgggcagat cccggtaata acccctttta acaggatact
    62401 cttgcataat actttttagg ggggatgaaa tatgttaagc taatgtcgcc agagtccaaa
    62461 ccagacataa agatatattc gcggtccctt tcggggccgg gatcaactgt tctcatgggt
    62521 tttcccggca gcggactggt cggaagcatc gcactccagt acatggtcga ccagctgaat
    62581 ttcgagcaga tcggcagtat caacagtaag tacttcccgc cgcttgcgat gatgaacaag
    62641 ggagtcatca acgttcctgt ccgggtctac gagaagggca acatctccgc gatcgttgca
    62701 gatatcccca tacaccccat gatctgctac gaagtcgcca atggtataat ggactggctt
    62761 gagcctttcg ccgtcaggga ggtggtcact attgcgggta tcatcacaaa cgaacccgaa
    62821 aaaagggtct ttggagtggc cagcagcgaa gaggcgctcc agcgcatcca ggattcaacc
    62881 attgtcctgc ccatagggag catatccggt attgccagca gcatcctcac ggagtgcaag
    62941 atccggaaca ttcctgcatt tgggctcctc ggcgagacga tcaatgctcc tgatccgcgg
    63001 gcatcagcag caacgatcga ggtcctgaac aagatgtacg gcatgaacct cgatgtacag
    63061 cccctgatcg aacaggcgga agagatagag tctacgatgc agaaactggc tgaacaggtc
    63121 aagtcggccg agacgatgcc caagaaagag catctgccga tgtatgggtg atcacgatgc
    63181 agtgctatgc tttaaccggg atctcccccc agattataag ggaattgcgg gagggcaagg
    63241 cccggacgct ggaactccag agcacccata atgtcgttac cctggcggga atcagcccgg
    63301 gagaactcgt gttcatgacc tccgttgatt tggaagatct ctcgcccggg gataccggca
    63361 ttgtcgtcga ggttctctcc ctcaacatca ccatgaagag aatcatggag tactcccatg
    63421 gtctccatta cgaggagagg gagaggatgt ctgcccgcat caaggtgaaa tgcatcgggg
    63481 cttcaacggt gaagagtgtg accgtcgagg gctttacccg tcccatcgtc gtcgatgtca
    63541 tgaaaaccgc gtgttaccat gcgggttgat ttcgtccccc tttttttccg ctcctttttc
    63601 ccagtccgcg ctggatgacc atgccggtgc gggattgggt gtgtccaaaa gaacgattaa
    63661 ttaccattcc cccgaaataa gtaatggaca aagagatatc ccgtgggctt gtggcttagc
    63721 caggatagag cgccgggctt ctaacccgga tgtcgggggt tcgaatccct ccaggcccgt
    63781 ccgatataac aaacttttct tgaataacac atccgctatt tgcactccgt acctttgtat
    63841 cgcggggaga agtgcctgct ttcattgaca aaacccaatt tcgaatgaca actttaaaca
    63901 gaaaagaaga gagaggggat ggtgtgaacc atcatgaaag aaggttgcct cgagactgac
    63961 aataccatca tgacagcaat agccgagatc gaggatgcat tcttcgatat cgagagtatc
    64021 aaaaccgata tccgcaacat ccagtatgac ctcgcagaac ttgaccggaa gcttcaggcc
    64081 gtgactgtcc atctcaagga agtccagtct tttttaggga ctgtctgcgc agtacctcca
    64141 accgaatcag gaggtgcccc acaggaaaaa tcattcaggc tctgattttt aatcccggaa
    64201 tctctattct ttcaggctta cccggcgtgc agggatcata tccacaagta aggtcctgcc
    64261 catttttcgc ccccccctgt tgctcccctg gtgtgaacgg gataatacca aagcgaaaaa
    64321 aggaaggaga atggttttat atctcctttt tttagggctg ctggttattc accaggagca
    64381 catcactgat gttgtgctgt cgctgggcaa gtttctttgc cttgaaaata tttttccctt
    64441 ccttgccgat cgcaaggcca cgatcctctt cccttacctc gacctgggca acctgtgcat
    64501 ccccctcacc ctcgaaaacc acggatgtca cttttgccgg gagaaaacag ttcctgatga
    64561 actgttccgg gttctgggca tattccacca cttcgatcct tttgcccatc acctccatgg
    64621 ccttcttgat gctggcaccg ctctttccaa tcgcaagtcc catttcaccg gggttgatga
    64681 caaaaatgat gcggttgttg cggtcatcga tcacgcagtc cctgcttcct gcgccggtca
    64741 gtttctcgaa ctgggacatc aggcgcatgc agtcttcgtt aagaagtact tcgaccatgg
    64801 tcgtcatgcc ctcttgagac tgagaatgtc agattcaccg ggatcgacaa cgacgagcgc
    64861 actcaccatg aaaggctttc cgcatgcctt ccccaactgc acgcttgacc cgtcaaacgt
    64921 gtgaacgaaa aggttttccc tggatttcag catttccaga aatttttccg ggcagttccg
    64981 ggcgacaacg accatccggg ccgatccgct ctcaatacac tgcgctgtca cgttctgtcc
    65041 gagcagaact tttcccgttt ttatggctct tcgcaaagag gcattaaaat ccattatgat
    65101 tctcctagtt tgagtggttt tgcaatgagt ttcacgtcgc cggtacccag ctggatgggc
    65161 tgaccaacga tcacgttctc ggtcactccc gagagctcgt caacctcgtt ggcgattgca
    65221 gcgtcaagga ggtggttcac ggtgacctcg aacgcagcac gggagaggac actctctttt
    65281 tctcctgcaa tcccatggcg gcctatctgc ttgacctccc catccatgca catcatgtcg
    65341 gcaacgagca tgatgtgccg gacgtcgacg aggataccct gttcgctcag cgtcgagagg
    65401 gcctcatgga taattgcatt ccgtgctgcc tcgataccca ggacctgggc tatctcgctg
    65461 atgttgttgg tgcgggttct cgtcgtatcc acaccctcaa cttcaaacac gtctttaagg
    65521 ttggagcctt cagtataaag gatatactcc ccgctctcct tgcggacgac gacccgctcg
    65581 atatcatcga taccctgcac aatcacgttg cgcacgtgtt cggcaagctg gaagaggttc
    65641 tggtagctct ccctgtcctt gggggagaag atcatggtgg cattgtttac gtctacctcg
    65701 cattcgaagt cacggtaatg gcgcctgtcc ctgatcttgc ggggtgcact atcgatgatg
    65761 tccgagactg caatcctccg cttttcgcag acctgcgtgt tgagctggac gacgatctgc
    65821 atgttctcca tatcgatgac gatatccccg aactcgtgga gcggtgctgc ctcgatctgc
    65881 cagctcacct cccgggcacg atccctgtcg gttgcgtact ctccctccag gtagatcgtc
    65941 attgtaggag tgctgggttc tttccgtgca tccatgatct cgatgagccg gggcagaccc
    66001 agtgtgacgt tgatctctgc cactcctgca tagtggaacg tccgcatggt catctgtgtc
    66061 cccggttcgc cgattgactg ggctgcaatg attccgaccg cctcgcacgc ctcaatccgg
    66121 gtatttgcgt attccctgat gacgcggtcg agaattgtgt cgaactgttc cctcgtgata
    66181 tcgcggtcag caaggtatgt acggagctgt tccttcgttt tttcagggag ctctgcagcc
    66241 gtgattgcct cttcgaattc gggctgcatt tcacacctcc tccttgagga tactctccac
    66301 gatccccttg acgtcgaccg gatcgccgaa actgctcttc atgggatctg tcccgtcctc
    66361 accgtagcag aactggatga tccggccacc tgttgtccgt accgtgccgt catacgccac
    66421 tttgaggtcc tggagcgcat tgatcattct cctctggagg tacccgctct gggatgtcct
    66481 gaccgcagtg tccaccagcc cttcgcgacc acctatggca tggaagaaga attccgtcgg
    66541 gttgagccct gacttgtaac tgtgggagat gaagccatgg gctgctgctc cccggtctcc
    66601 cttcctgaag tggggaaggg tacggtcatc gtatcccctc atgatacgct ccccacgcac
    66661 cgactgctgg cccacgcacc ctgccatctg ggtcaggttc agcatggacc cccttgcacc
    66721 cgagactgcc atcacgacgg cactgttccc aagtcccagg tgacggcctg caatttcacc
    66781 ggtccggtcc ctggcctttc cgaggacctg catgatctgc atctcaaggg tctcctcggg
    66841 tgtccgcccc ggcatcgcct cgagttgtcc gtcctcgtag atcctgatcc tgcgctggac
    66901 gtctgttatg gcgttccgga ggacttcttc gatctggccg tactctgtct tggaaaggtc
    66961 ttcatcgtcg attccgaatg aaaacccgtt catcatgatt gccctgatgg caaggtgagt
    67021 tatatcgtcg atgaagtctg ctgccctctt catgccatac tgccggatga tgcggttcac
    67081 gatctggccg tcgaaggctc cgatcgcctt cttgtcgatc gttcctgact cgagatttcc
    67141 gtcgatgata cggacgtatg cgtcccggtc gcattcctgc cgcttgcatg tctcgcaatt
    67201 ctggcacgaa ctcgcccgga acaccatgtt cagttccttc ggaaggacga tcgagaagat
    67261 ctgcttgttg ctccagtaag ggacaccatc cttgaccatt cccgggggcg ggagatgttc
    67321 tatctcgatg ttcttcagca ggtagagtgc ctcctgcttg gtatgccact tcagctggtt
    67381 cgtgagcatg aatatgccgg agacatggtc atggatgcca ccgatgatgg gtccgccgaa
    67441 cctcggtgag aggatattct cttcgaccgc aacgagaatt gccgcctcgg cccttgcctc
    67501 ttccgtctgg gggatatgca ggttcatctc gtcgccgtcg aaatcagcgt tgtacggcgg
    67561 gcagactgcc gggttcaacc ggaacgtcct gccatccatc accttcacac ggtgagccat
    67621 gatgctcatc cggtgcaggg acggctgccg gttgaagagt acgatatcgc catcccttat
    67681 ctggcgttcc acgacccagc ccggctcgag catctcggca accgtctcga ggttgccctc
    67741 cgcgagcctc attctccttt tgtcgggccg aatcacgtaa ttggcaccac agggctggga
    67801 gagcgagcgc ctgaccggac cattccgcac catctgcctc agttcctcga tgttgtaggg
    67861 cgtaacagtg accggaaggg tcatttcgtt tgcaacggcg aggggtattc ccacctccat
    67921 gacactcaaa ttgggatcgg gggatatgac cgttcttgcg gagaaattga cccttttccc
    67981 ggaaagtgac ccccggaacc gtccatcctt tcctttcagt ctctgggaga gcgtcttgag
    68041 cggtctcccg ctccggtgcc gtgcaggagg acaaccggcg acctcgttgt ccaggtacgt
    68101 cgtgacgtgg tactgcagga gttcccagag atcctcgatg atcagctggg gtgccccggc
    68161 atcctgattc tccttgaacc tctggttgat cctgatgatg tcgacgagct tgtgggtgag
    68221 gtcgtcctcg gacctctggc cgttttcgag gatgattgat gggcgcatcg tgacgggcgg
    68281 gacgggcagg acagtgagga ccgtccattc aggccgggcc acatcagggt taataccaag
    68341 gtgcctcagg tcctcgtcag ggatcttctc gagtctcgcc ctgatgtctg ccggggtgag
    68401 cttgtgctca atctttttcc catcctcgat gatgatctcc gagaacgtcg tcggtttctc
    68461 gaagtttatc ttcagctgct gttcaccgca gtagggacag acccgctcct tcttgatgtc
    68521 cttttccgag aggacgtccc cggtgagatc gtcctcggtt ccgacgacct tctcgatctc
    68581 ttcgggtgag aggaggagcc tgctgcaact ccggcaggtt accctgagca gtttccggat
    68641 cagccgtgta taaccaacgt gtatgacggg ttttgcaagc tcgatgtggc cgaagtgccc
    68701 cgggcagtcg ctggctttct ggtcacaggt cttgcagcgg aggcccgggt cgatcacacc
    68761 gaggttcaag tccatcaggc cctggggata ggggaatccg tcgtcgtcat acgtgtctgc
    68821 ccagatgatc ttcctcacgc tcatcgtgcg gatctccttg ggtgagagga gtccgaattc
    68881 tatctttccg attctctttg ggctgggcat tgttgttcct cctagaccac gtcctccagc
    68941 ttgaggcggg gggcgattcc catgctcttc atctcgtcga gcaggagctt gaaagcataa
    69001 gacatctcga cctggtagat gtcggtctcc gccccgcagg caaggcagcg ggtcgtgttg
    69061 gacttgcggt cgagcatcgc caccattccg cagcgtgcgc agacgtattc ctgtactttg
    69121 tcggattcgt cgaggagccg ttccttgagg gccattgctg caccgtggcc gatcatgaca
    69181 tcccgctcca tctcaccaaa ccggagaccg ccttcccgtg cccgcccttc tgtcggctgg
    69241 cgggtgagca cctggacagg gccgcgcgaa cgggcatgca tcttcgaaga gaccatgtgg
    69301 tagagcttct ggtagtagat cacgcccatg tagatgtctg cagaaaacct ctttcccgtg
    69361 atcccatcgt acatgacttc cctgccggta tgtgcaaagc cctgcttctt cagggacgcc
    69421 cggaggtcct cttccctctc tcccgaaaaa gccgtgccgt tgacacgccg cccttcgagc
    69481 gcgccgacct ttcctccgat catctcgagc atgtgcccta tcgtcatgcg gctcgggatg
    69541 gcgtgcgggt tgataacgag gtcgggtgtg agcccggact cggtaaaggg catgtcctcc
    69601 tgcggggtga tcaggccgat cacacccttc tgcccgtgcc gggacgcaaa cttgtcgccc
    69661 acttccggta ttctctggtc ccgggtcttg accttgatga ggcgggaact gttctctcct
    69721 tccgtgatga tgacggtatc cacgatcccg cgttcgttgc tgcgcattgt caccgacgtg
    69781 tcacgcctct tctcgacggt gatgaggtca ctcgttggct cttcgaggaa ccggggaggg
    69841 gacgtctttc cgatcagcac gtctttttcg ttgacaacgg tctcagggtt aatgataccg
    69901 tcgtcatcga ggttcttgta gctctccgcc ccgtgtgcac cggtcacctc ctcgtcgggt
    69961 atctcaatgc ggtcgacctg tccaccggga tatctcctct cctcgccctc gtatgtcctg
    70021 aaaaagtgtg agcgtccaag tcccctgtca atcgaggcct tgttgaaaat gagcgcgtcc
    70081 tcgatgttat acccctcgaa cgacaggatg gccacgacga agttctggcc tgcagggcga
    70141 tcatccgatc cgatcaggtc cgaggtctgg gtatggacga gcggtttctg gacgtaatgg
    70201 aggaggtggc cccgcgtgtc cggacggatc ttcatgtttg ccgcaccgaa cccaagggcc
    70261 tgcttgacca tccctgcacc catcgtcacc ctcggacttg cgttgtgctc cgggaacggg
    70321 acatgcgctg caccaatccc gaggatcagg gaagggtcaa tctcgaggtg cgtatgctcc
    70381 ggagtgatgt cttcagggtt gatggcgatg tagaggtcct cttcctcctc cgcatcgaca
    70441 agttcaatca gtcctctcct gatgaggtta tcaaaatcaa tctccttttt ccggagtttc
    70501 tcgatgtctt ccacggtcac gaggggtttt ccctgggaaa ggacgatgag ggggcggcgt
    70561 gcccttcccc tgtcggtgtg gatcacgaca tcgttattga actccttgtg ggagacgttc
    70621 acctcggtcg agaggagacc ctgtctcctc atcgtcctta tctgggaaac gagggttttt
    70681 ggatcatcga cgagcccgat cagtgccccg tccacaaaga ctcttgcctt cttcataggg
    70741 catccccctt gatgtgttcg acgccaagcg agtacagcgt gtgaatcact tcttcctcgt
    70801 caggaacccc cctgctgatc tcgaccatct gcgcaaagtt cttcacgagg ccacagttcg
    70861 gaccttccgg tgtctcactc ggacagatcc tcccccactg ggtggggtga aggtcacgtg
    70921 cctcgaagtg cggctgggac cgggatagcg gggagatgac cctgcggagg tgggataaaa
    70981 cactcatgtg gtcaaccctg tcgaggagct gggatacccc tgtcctcccg ccgacccagt
    71041 tgcccgtggc gaggggatgc aggagacgtt cggtcaggac atccgcccgt accgctgtcc
    71101 cgatcgagag gtcacggtgg cgcatgctcg ccctttccag ctgatacttg atatcccgcg
    71161 tgagcctgtt gagcgagatg cggaagaggt cttccatcag gtcaccggca agtttcaacc
    71221 tcttgttcga gtagtggtct ttatcatcaa tccgtcgttt tgcaaggacg aggtcaaaac
    71281 atgcttccgc catgcgaccg aggaagtgag cctttgccag cctgacctct gcaacagcct
    71341 ccttgtatcc ttcctcacct tccttgaggt tggtgggcat gagatagttg aggtggggga
    71401 ggaggtagtt gtcaaggacg aactctgccc ttttccgctg gtagtcacgc gtctggttcg
    71461 gggcaagttt cttcccgaca tacatgatcc cggcttcgac gctgtcgcac tcgctctcct
    71521 ccaggttctg catcatgaac gtgaggatat cctcgtcggt tgacacggca ctgacgatat
    71581 cgtggtcact gaccatgccg agtgccctca tcaggtccac gaaccggagg tgcccggcaa
    71641 cggaggggaa agaaacctcg aggaggtttt tcctgttcct ctccacgaca accagtgccc
    71701 tgtatccccg gtactgggaa aagacctttg ccacgtagat gcgctcgttg taccgctctg
    71761 tatactcggt catgatcttg ttcgaggcca ggtcctccag tgtcatgagg acccgctcgg
    71821 tcccgttcac gataaaatag ccaccggggt caaagggatc ctcgccgtgt gcaatcctct
    71881 cctccggcga catgccatag aggttgcatg ccaccgatcc caccatgatc gggagctgcc
    71941 cgatcgtggt gatgaccggt tcctggcgat cctgcccctg gacgagtgtc agttccagct
    72001 ggatgggtgc ggcataggtg aggttgcgca agcgcgcctc gctggggaag agatctccct
    72061 gcgagccgtc cgcctcgcgg acgagcggtt ttttcacctc gacacggccc agttccaccc
    72121 agaccggttc attgcttctt ccccttatct cgatgtcagt ctcgatgaca cgctgctcgt
    72181 tgacaacctt ctgcaggttc tgcgtgagaa aattgttgaa agagtcgagc tggtggcgtg
    72241 ccacgtgctc ctgggaaaaa tatgcctttg ataatacgct cctgtcaatc agaactatca
    72301 gccccgcctg aatgtgttct tacttcttcg gcctctttac gaccagccga aacgattcgg
    72361 cccttccagc tgtgtgggac gtgcggatga tgcgtatgac atccccgacc ttggctccga
    72421 ttgccttcac cgcaggatcg tcatggtaaa tttttggcaa ttgctcgctt gtaatgtggt
    72481 agagagaata gagatgctgg atttcctctt cactcatgat cttatggtca ggaaccatga
    72541 tgtgttccag tacatttaac ttgatgctca ccgaaaaccc cctttctgtc gtgaattttt
    72601 cttcccgtcc ttcccggtaa aaccgctggt tttaaccgcg gtagcgggcc cggagggatt
    72661 tgaacccccg accacctggt taaaagccag gcgctctacc tagctgagct acgagcccac
    72721 cgtcttctca cacgcagcat tattacaacg cgggaaaact atataaagat atttgcctaa
    72781 cctattagcc tcaaattaac tgcctgacgc gaggcaggcc ttttaaatca ctgtcactat
    72841 tctgacaggt gtttttcgaa tccaagactg atatgaaatt ccagaagcct tgcatcaagg
    72901 ctcttttttc cttttttctc cgtttccgtg tcccgtcccg gttcctgcac caccggtccg
    72961 gtcacatctt cctgggattt aatctctatg tccgttgacc cggccttctc ctcagctttt
    73021 tcgaggtttt cctcgccagt tacgcttcct gtcctgccca aatcaggggg taccccctca
    73081 ctctgcgcct cttcccccgg tccggcatcc tctgacccat ctcctgcttt actcttactg
    73141 gcttctccct cactcccttt gcctcctgct tcatcctccc gggagaggat cctggtgata
    73201 acatcaagca ggagggaggt attgatgggt ttcgtgagaa cttcgctaac attgaggtga
    73261 tgataggatg cttcctctga aagagtcctc cgggcggaaa agacaatcac aggaacctgc
    73321 acaaggtccg ggtttgccct catcctccga agggtctccc acccgtctat tggttccatg
    73381 gagatatcga ggaggacaag atccggaaca ccccgtgaga ggagatcgag cgcctctata
    73441 ccgctcatgg cagatatcgt ccgaaaaccc cttttccgca ggatggcatg aaggccttcg
    73501 acgatgaacc tgttatcatc cacgatgagg atagtatgtt ccatgattcc cttcggtctt
    73561 ttcggacggg gctcctcctt cccgccccgg ttaatcacca tttgaccggg ggagaaaaag
    73621 gtatttttga tcggttccct ctccggtgga gagggtatcc cttaccggct gtattaataa
    73681 ttacatatgt tttatatata attagagaat ggtccagttg gcagagtggc tcggggagct
    73741 ttccccttct ttttctccaa aacccactac tgtacagagg gctgcccggc acctctccaa
    73801 aatggaacgc gccaaattgc tctcggcaga tattgacaag atgagaactg ccgagggccg
    73861 gtggtacgag gcaatcattt acgagacgtt catcgacctc gcgacacgca gcgattcaat
    73921 ccggtacctt gccctgaagg gtgcggatgc gccacgacgg aggagaaccg cacgtctggg
    73981 tcagaacggg atattttact cccgttcggg cgacatcacg atacgtggga atggccagga
    74041 ccttgcagag tttgatctcc tcatggtcga tggagagaac aggatcactt ttgcagaagt
    74101 cctcacatcg ccctccgact taaaggagtt cgaagtcgag attgagtata agagaaacct
    74161 cctgggttat ctttttgatc agcaggaagt acctttcctc ctcgtatcct ccttcaacgt
    74221 ggcaaactat tctgccggcc ggaggatcat caggagtccc tatacctatt atttccagac
    74281 tgaatcctgc gagaccatca agacacggat cgatacccgg cagctgacca aaagaccggt
    74341 ctgggatttc acacctcacg caaaaatggt cgatgcagcc gggttctcat tcaggcgccc
    74401 cttcgattac cagaaattcc atgactggca gaggaactgg gtcttttcaa atgtctccaa
    74461 cgagatcgat gtgaaaaagg tcaaaaatcc tcacgagact gctccccttg tcaaaaaaat
    74521 tctctacggc agcctctacc cctcagcagt ccggagggtc tgtgaggact atgaattctc
    74581 gatccggggt aaaaaagtcg ctttcaacga tatcaggaag aagtactcga aggtcatcct
    74641 cgcaaccgat ctcccggggt acgaacctct catatacctg cggtcgaggg agaagagaga
    74701 gtacctcaag atggttcagg accgggatgg aaatttcaag ttcgaacgga atacgccgcc
    74761 gcgtgtggga tttttcctct ggctcgagtc gcttacgccg acactgggct cgcggatagc
    74821 atcaaagata ctcgaggcat tttccccgcg atgaaaatgc cctccagggc actgtttgca
    74881 tccccctcga aagcaacctg aagacaaaac gtgtcaggaa taatccgtga gacatttttc
    74941 atccctttct ttacagtgcg gatgaaaaca tttctgcgaa aaaaataggt aaagaattgt
    75001 ttttttcaat cgaggaggac tgtaagtgcc tcgtctgcgt atgcatccat tacgtagggg
    75061 atgccggata tgcgggaggc ctcctcggtg agagccatga catcgctgcg tgagatcgag
    75121 ctgatggcaa agttcctgct cccggccatg atctgctgga gcccgatcct gaacttctgt
    75181 gcgtacgtgt aaatcccgat tgcccccatc ggtatctcct tgaaacgggc accgtacttc
    75241 tcgcggagct cttcccacgt gacaaaaatc tcttcagggg ttgaaccgaa cttcgagacg
    75301 gtctttggaa ggtctccatc cttcaaccat ttttcgatgt tcttgcccac cattcccggt
    75361 atcatgaggc cgcggcccat gcacactgcc ttgaagtacg ggctccccat tgcaagggcc
    75421 ttgaagacac ccggttcgtc cgaaaaaccg cctgccatag cgaggtcggg cacacgcaga
    75481 cctctctttt tgagcagttc agcatactcg tacgcgagcg actggaggta gaatgtcggt
    75541 ataccccact cgttcatcat gggccacggg ctcattcccg ttcccccggg tgcaccgtca
    75601 attgtgagca ggtcaatttt tgcttccgat ccgtacctta ttgccattgc gagctcgact
    75661 gcggaatagg caccggtctt cagggtaacc ctcttgaacc cgatgtcccg caggcgatcg
    75721 acttcctcga ggaatccttc cttgctgatg aaacccaggc gtgaatgtcg ctcgaactcc
    75781 ttgatggcac ctgccttgaa agccgcctgg acatccggga gggtcggatc gggaaggacg
    75841 atgtagcctc tcttcttgag ctcgagggct ctttcaagtg tctttacctt gatctctcca
    75901 ccgatgcact ttgcaccctg accccacttg agttcgattg tctcgagatt gtgcctggag
    75961 gcaacgtact cagctgtccc gaggcgcgta tcctcgacgt tcatctggac gagcatctct
    76021 ccatacccgt cccagaactt cctgaatatc tcaatcctcc gatccatctc gggtgacttc
    76081 ttaacctttc cgtggttgtc aagctggagc gcggggtcca caccgcagac gttttctccg
    76141 cacacgatgg tgattcctga aattgcagcc ccgattgcga aatgttccca gtttatccgg
    76201 gctatgtctg ttgaccccag tgccccggtg aatatcggga gcttcatcct gactttttta
    76261 tcccacccgt actccgtctc cgtgttcacg gagtaaaaga ctgcactgtc gggcccaatc
    76321 tccgttcctt ccggtagacc gcgggcaccc atggcatatc cctggatgtt gaggtgcgag
    76381 tagtcgacag ggtagttctt gtctgccccg gccgtgatct ctccgaaagg tccggggtat
    76441 aaaacttccc gccccctgaa ggaggataac catatttcac agctcccctt gcacccgtca
    76501 acacaccggg tacagattcc tgataccggt gcaacattgc gcgacctgtt tgttgtacca
    76561 gttgcctcgt ttgcatttgg ttgtcgaagg ttcatgcttg tctcctgcgt tctcaagaaa
    76621 tattaacata gagtggaatg agtccaggca ttcgagccca aaccaggaat agttttatat
    76681 tttaaagatt tataagcgct tgccttcctt cactatatat atttttcaca tcctcgttgt
    76741 ctgcctgttt atacttccgg agatcccata gtggcaggat tcttcctaaa tagtccctga
    76801 aaaacagatt taaaattttt atcaggagat actgacgagc tcgtattcac gcgaccccag
    76861 tccaatctcc ccgccatacc gtatctgcag gtatccatca gtattctttc ttaatcccct
    76921 gaacttgtct tccccctcgc gaaggttctc atggagaaat gatccttccc ttcccttctc
    76981 cccgttgacc aggtcaaatg atgcggcatc gattgcaaca gggtctttgg atgcaaggat
    77041 cccgatatca ggaacgatgg gcatgtcact ccaggggaca caatcgcagt ccggggtgat
    77101 attcacgaga aagttcatgt accccgcttt ttcctccttt cccgagacag ccccccttgc
    77161 atattccacc atgcgttcca cgaactccgg gatttcggtt tcccagtcaa catctattgc
    77221 atgagacggg cataccgtca tgcactcgaa acaccctatg caccgggaat actggatctt
    77281 tgcacgtggc ttcttccttt tcttttcaaa ggttatcgcc tctcccgggc agactgcgat
    77341 gcacctgcca cacccggtgc acctctcgtc gatgtgcatg ggccgggcac agtgctgggc
    77401 ctgttttccg gcagggggtg cacaacccat tgcgaggttc tttatcgcac cgccgaaccc
    77461 tgcaacttca tgccccttga aatgcgagag gacgatcatg gcatccgcat cggcaatgtc
    77521 tcccgacacg aagactgacg ggaaatgccg cagatgtacc tccacacgac gccagttctt
    77581 cccgcgcagt ccgtccgcga tgaggagagg agccctgacg actgcatagg caaacccgtg
    77641 ctcgattgcc gtgacgaggt gatcaactgc attggccctg ctgcccctgt acaatgtgtt
    77701 tgaatcggtg aggaatggtt ttcctcccgt ttccctgatg cagtcgacca cctgccggac
    77761 atggaccggg ttgatatagg aatcattgcc ccactcgcca aagtggattt tgactgcagt
    77821 caggtcaccc tgggatataa ggtccgggaa ccctgccgca tggaacagcc ggtttatctt
    77881 ggatagggta ttctggccgg gatcccgtcc cccgacccgc gtaaaataga ctttttgtgg
    77941 catatcattc acactcctct gaaccagcaa tcagggttgg gcaatttatc ccatataggt
    78001 ataccttccc ctctgctctg aatcagtacg gttgttcatg cgatggggat tctatcgcga
    78061 gataactcta ccgggcgcct ggaaaatcaa aattcgctgt tattcgtaca ccaggaaaac
    78121 gaatagcgac ttttcgaggg gtcatttggt cccgggttgt ttcatccgga acacccggga
    78181 ttcccaccgt actcctcccg atatctcttg agaaagagtg atgactcccc gttatttgcc
    78241 cggaataaac ggaaagactg tatcagggct gcatacaagg ccctttttta tgtcttttac
    78301 cggtaatctg gaaaaaaagg gataaggatc gtttccggac agtcaaaacc tattctctct
    78361 tgcccagttc gtggtcaagc cagaacatgt gtccaacgac atccttcagc atcctgatct
    78421 gggcaaggat ttcgcttgca tttgcctctt cctcaacctg ttccttaacg aaccatgcaa
    78481 ggaagttctg cgtggcgtag tctttttcct tgaccgcaag atccatgatg ccgttgatca
    78541 tcccggtaac ctttttttca tgttcataga cctgttcgaa gacctcgcca acggatttcc
    78601 actcggcctt gggagcatca atccgggcaa gcttcacagt tccccccgcc tcgatgatgt
    78661 agtcaaaaaa tttcatcccg tgtgccttct cctcttctga ctggatcctg agccattttg
    78721 caaaaccctt catgggaatg gtctcgcagt aagctgacat tgccaggtag aggtaggcag
    78781 agtagagttc ggcattcaac tgcttgttca gcgcttcctc gatacttttc ttgagcatgg
    78841 tttactcctc ctcaccacgg atatgtccac ttcccttccc tttaatgctt ctattccagc
    78901 actttccatc gtggtccgaa caagtcttac gcgggaaagt ctttctccag ggttggaaaa
    78961 gagaggaaac tattgcccga caatcacccg ggcattcgga tcaaagggat ttgtccttat
    79021 cgcaagcgag aagagatagg ggtaatttcg cttgaggtgg tgcatgtatg caagccattc
    79081 gaaacagagg aggcggtaga cacgttcggt gtccttttgg agatgggcaa cgtcgctgtc
    79141 cgggatggca cggagatctt ccctcctcgc gagttcttcg cccagatggg tcacggcccg
    79201 caggagctcg gtgaatgtct ggtgttcgag gagcatgggg ttttcaagga ggcgaagcaa
    79261 aaaattcctt ttttccttca ggaatgcccg cattgactcg agatcctgcc tttcggggag
    79321 cacgcggaac gggtatgatg aaaagacctt tttggtcctt tcaaattctt ggtcgctcca
    79381 ctcttccctg attgtgagcg catcggcaac acgggcgatg tccggatcct tccgggcaat
    79441 ggcatgcagg agatcggtcc ccatttcaga aaagaacgtc ccgattacca tgttcaactt
    79501 ttccagcctt tccctccgcg ctctcgtgct gagcagctcg tttaaaacga gtgtgacgag
    79561 gaggacattg atagggagaa agccaagggc attgaagacg taaaaatatg tattttccgg
    79621 atccccgagt atgatgaact tgaggaaata gaccgagaat gaaaagaaaa cgaggaatat
    79681 ccccagtttg acctgccagg agtacttcat ggtcaccttc atacctctct ttggctcttt
    79741 tcccgagagc gtgaatacat cctgaattcc tccctattgc ctccctgttg cccgcgtcag
    79801 ctcttcgacg ttgctcctgg taaaaaaccc gtcaaatccc tcgtacctgt ggatgtactc
    79861 gttgactatc atcgtgtggg gtgatggcat ggaaaaagtc tgtttgagtc cctcctcgcg
    79921 ggacccgaca agtgcaacca ggaattccat gccgtgggac accagttcgg caaagaccgt
    79981 atcaatgtcg tctgtcgaga atgccatgtg atgaacgcgt gtcccatagc cgtggatgaa
    80041 gttctcggtc ggcccgggat cttctccctc gcggtagggt gcaatgcctg atgtaaagac
    80101 catggcaaat gcatcatcgt tcaggcgggc gacactcgtg atggagttga gtgacttcac
    80161 aaagacagca aagtcaaagt gatagctggt cagggagaga aactcgagga tcgctgcgtt
    80221 ccgctctttt gcccttaccc gtgtagccgt atgatcgagc ttccctatgt tcgcaaggta
    80281 ggaaaaaccg ggcttttcaa gagtagcggg acgtttttct gccccatctg gtgcaaatga
    80341 gcgtccccgg cccgtccatt caataaaccc gagggagttt cccgtgtagg gggagggaac
    80401 tgtctggatg aagcggaaat cagggcccgt gataatcccg tctgtctgga aacgaacact
    80461 cctctcccgc tggatttccc aatacgtatc gatgtcccgg cacccaaaga taaatgtctc
    80521 gagccgggta ctgggaaggt tccttgctct ttcggcctgg ttaaagggta gaaaagggtt
    80581 ttcacccgca aggcggctct tgacaatgac ggcaggagaa cccggtgtcc ggagcgtgta
    80641 agcccgtacc aggggagtgg aaaactgctc atcgattgtg agccccgtga atgccaggag
    80701 ttcggctact gcggactcga gcctttccct ttcggtgttg atgacaacag cttcgagatc
    80761 tccaacgagc ccatcaaggc ctgcttcctt cctcgcctgc atgacgtgcg gcagccgggt
    80821 ggcaaggtct tcctcctgcc acttcatgaa accttcatcc cctttttcca gggacatgct
    80881 gttttcctcc tgtttttcca ttttcatctc tctccgtaac cggatgggtt tgatatatcc
    80941 ccccggtaaa tgctggtatc ggggttgccg cactatgggc agattctcta acactcactc
    81001 aggctgcgta tttttccggg tctgcgtcaa attttttctt gcaccccgga gcacagaaat
    81061 agtaggtttt tcccctgtat tccgtcctga aacgcgctgt cttctcatca actgtcatcc
    81121 tgcataccgg gtcaatggcc atggtttttt ccccctggta aacgatctcg gagaacagga
    81181 ggtatatacc ttttgagggt gagggagagg gtgacgacgg ttactgaact tgcggccatc
    81241 gccagggccg cgagctccgg ctggagcatg tatcccgtga agggaaaaaa gacccctgct
    81301 gcgagaggga tgagggccac gttataagcg aatgcccaaa agaggttacc tcgtatcctc
    81361 gccatcacct tccgggatat ctggagtgcg gctactgcat ggaggaggtc gtcccggatg
    81421 agaacgatgt ctccgctctc tatggccacg tctgtcccgc cccctatcgc gatcccgata
    81481 tccgcctgcg cgagtgccgg ggcatcgttt accccgtcac ccacgaacgc gaccaccctg
    81541 cccgattcct gcatcttcct gacttcacgt gctttctctt cgggaagtac gccggcaatg
    81601 acattttcaa ttttcagcct ctctgcaatc gcccgtgccg tccggatgtt gtccccggtg
    81661 accatgctga cggatagccc cattctcctg aattcttcaa tggcatccgg ggacgtatcc
    81721 cgcatgggat ccgcaatacc aatcacgccg gcaatggtcc cgccggtcgc gacagcaacg
    81781 accgtctttc cctctttacc aagtcgcgaa atggtctctt ccgcatcagt cggtaaatgt
    81841 atcccgtttt cttccagaaa agcggcattt ccaatcacta cctgctcccc aagaacacgg
    81901 gccgagacgc cctttccccc atgaaggtaa aactcctccg cgtcaagggg aggtgctccc
    81961 ccggccgctg cagcgtcaac gattgccctt gcaaggggat gttttgagtt tttctcaaca
    82021 gctgctgcaa gcgaaagcag ggttgctccc tgtgtgttca agggaacgat atccgttact
    82081 accggctttc cttcggtgag tgttcccgtc ttgtcaagaa ccactgaatt gacccggtcc
    82141 gcaacctcga gtgcctcgcc attcctgatg agaacaccga gttcagcgct cctcccgatt
    82201 cctaccgtaa ccgccgtcgg ggtggcaagt cccagcgcac acgggcatgc cacgaccagg
    82261 acagagacga atgcagtcag ggagaaagtg agaggttcgc cgaggacaag gaaccagacg
    82321 agaaaggtaa gggccgcaat tgccaggatg accgggatga aatatgccac cacgccgtcg
    82381 gcgatcctct ggacgggtgg ccgggatgcc tgcgcatctt ccacgagggc aatgatacgg
    82441 gcaagcaccg tctccttccc aaccttctgt gccctgatcg tgaggacacc attggtattg
    82501 atggtcccac cgatgacggt tgatccggga gccttgaaca ccggtacagg ctcacccgtg
    82561 accatggatt catcgacaga gctttcaccc gcgatcacgg tgccatcaac cggaaccttt
    82621 tctcccggcg tgacgcggat gaggtccccc accctgacat cctcgatggg cacttccttc
    82681 tcttccccat cggagatgag ggttgcagtt cttgggcgga ggccgatgag tgcctttatc
    82741 gcatcggtgg tcctcccctt ggcccgtgcc tcgaggtatc gccccagcat gaggaacgag
    82801 gccagcatta atgccgtatc gtacagcatg aaatcgtggg aaaggccaat tcccacggtg
    82861 gatgccacgc tggcgccaaa tgcaacaccg gttcccattg catacatgac atccatgttc
    82921 agtgtcctgt tccgcagggc ggatacagcc cccctgtaga tgggataggc gacgtatgcg
    82981 aacgcagggg tggtaattac gagcatgagg aacgagaggg tgtgcggaga gaggggaggt
    83041 tgtgatatca tcaggatgaa ttccggaata cttattccaa agcccaccag gaaacgacgg
    83101 gccttatccc cgaggtcccg gcgacgtgcc tcctcctcgg caccggtggt cacctggtcg
    83161 gcaagcccca ggtactggta gcctgcgtcc tcgatggctt tcttcatatc gtcaatggtc
    83221 gtgatggacg agttatagac cacatatgcc ttctctgtcg agaggttgac cgtcgcacct
    83281 gccacgcccg ggagcgcttt gagcacggcc tcgattgtct cgacgcaggt tgcacagacc
    83341 attcccccga cttttatcgt ggcctggtca tagacaacct ggtaccctgc tttccggact
    83401 gccgcctcga tatctgcgag gtttgttatc gatggcttgt aggcgacgtg ggcggtttcg
    83461 gaggcaaggt tgacagtggc ggattcaaca cgtccctctc cttttagggc cttttcgagg
    83521 tttactgcac acgtggcaca gctcattccc gatatccgga gttcggccga ccttttctcg
    83581 tcctcttgtg tcatggttcc cttcctctcg tcagcagaat gcacctgctg gtaccttatg
    83641 cagctaatgt cattgaaagg tattttaatt ccggcccgtt tactcgccaa acgtgaacga
    83701 agaagattgt acatttgtat caaagtgaag tccggacaat cttctgtcga taaaggctat
    83761 tctttggaac ttcaagcggg catgaaaatc caatcggaac cggaggaccc ttacacccgg
    83821 tgaggatgtt ttcgccctga tgacacgatg accccccggt tctttatttc cagctttata
    83881 cctgaaccac cgtttgcctt ataatcgacc cggacacaac tgcccggtac ttctctcctc
    83941 attttacagg atagcgagaa aaacggcgta gatgatgacc tgggcgagcg tgaggggcag
    84001 gccaatcctg atgaattcaa agaacgtgat ggtatacccc ttcttctcgg cattctcgat
    84061 gatgatgacg ttgcttgctg ctcccaggat agtgagattg cctgcaatcg tgctcccggc
    84121 agcaagggcc atcagggatg ccacgggcat tccctctttc ataatgagcg gaagaaaaag
    84181 cgcgacaaaa gggacgttgg agatgaactg gctgatacag acgcttgtgg aaaggatgag
    84241 aggaatggac gtgagggact ggaaatcaat tcccgactgg aatatcccgg tgttgtaaac
    84301 gctctgcatc aggacaaaca tcgcggcaaa gaatgccagc gtgggccagt caatggtttt
    84361 tataattttt acccgttccc gggaaaggat aatgatgggg gcggcacctg ccagtgcaat
    84421 gaccgagaga ggaatgagaa aaggtcctgt tatgaccctg acaacgatca ggagaatgat
    84481 aagagcgagg gagatgcggc taatccgcgc aagatttttg ttcctgatcc tgtcctgcct
    84541 ctcgtcgaaa ctgcactcga atttcccctc gccgacatca taggtcagca gaagataggt
    84601 gacagcgagg ctgattgcgg tcgggagacc gaggtacacg aggaaggtca ggaacggctg
    84661 gggcagctgg ctgtaggtgg caacgagcag gttctgggga ttgccgatcg gactggggac
    84721 gcttcccgtg gttacggcaa aacagagggc aaggagggct ttccccggag ggagaccaaa
    84781 ccgacaggca taggcgatga ccaccggggt tgcaatgatt gcaaccgtat cgttcatcag
    84841 aatagcggag aggagcccca tgaagacgag aatgaacagg atgaactgcc gcccggaccg
    84901 ggccttcgaa aagagccgga acgcaagtac gtggaggtat ccgctctctt ccagggcctc
    84961 tcccacgatg aacatcccga ggagaaagag catgacatct gggttgatcg caaagagtgc
    85021 atcacgcggg ctgatttctc caaggaaaag aacggcaagt gcacccatgc acatcacctg
    85081 ccagatgcgg aaccggaatc tgcccacctg gcgtacggcg atgaggataa ataccacaag
    85141 aaggacgatg actggtcccg gggggaggaa agtgccctgt gtcacggcag gtcaggtctc
    85201 gatcaatttt tctccacgac ccagtggagg agaatgccgt tatcgatcct gtctgcggca
    85261 aagagggtga gtcgtggaaa gtcttcctcc cgcacgaagc ccggaccgtc cgcaggtgtg
    85321 ggggcatttt cccccccgat gacgatattt ccgataaacg tgatgaattc gtcgacgagt
    85381 ccggcagcaa agagtgcacc gatcagtctt ccgcccccct cgaccatcag gcgccggatt
    85441 cccctcatcc acagtccctg catcaggaca gggaggtcaa cctcccgctc cccggcaacg
    85501 atcacctctg caagtgcaga gagatcctcc ctctttttcc ggtcggaacc ctcgcagcac
    85561 gcgatgatcc tcctgcccgg cccccggtgg aggatggctg catccagggg tgtgcgggcg
    85621 cggcagtcta cgaccacccg aacggggttc ccggggagtc cccttcctgt gcgtgccgca
    85681 acaagctcct gtgacttgac ggtgagggac ggatcatccg caagaaccgt acctatgccg
    85741 accatgatgg catcgcattc cgccttgaga cggtccaccc gggaaaaatc attttttccc
    85801 gatattttca cctgccgtcg ttcacgcgtc gagatcttcc catcagcact catggcgagg
    85861 tttacgatga catggggacg ctgcatagtc tcacagaatg tggacagcat atcctcttga
    85921 atgtggcgga accgggggaa tggacaggct cctcttcgtt ctcttctttc tctccacccg
    85981 ggcgtgccac aaggaaccgc caaccctgct ggacatgatt tgtgataccg gaggtatctg
    86041 ccggtatagg gactattcct tcactcgcct tcccgaagtg caacgtatcg catggattta
    86101 tagaagaaga agccgacgat gccaaacgtg acgagggggg agagccagtt agggatatgg
    86161 gcaccgaaac tgtcgagaac catgatgatt cccagaacca aaatggaata catcgcccca
    86221 tttttcagat atctgtattt cctgatgttc tccacgttcc tgaccgtcag ctccctgaca
    86281 acgaatgcac ccataccgtt cccgatgatg ataaggggga cagacagtgt gaatgcgaat
    86341 gctccaagga ctccgtcaat cgagaacgtc gcatcgatca cctcgaggta aaaaattttt
    86401 gagatgtctg acatatctcc ccccaccatt ttcttctcct gctcctcggc attctggcgg
    86461 aaaccatgga cgatgaagaa cgcagttgac cccaccactg caccgaatgc catcatgggg
    86521 ttcaccttga gggcttccca gacgagaagg gagagcagga ccgagacaac ggcaaagaac
    86581 cacaccccct tggttgcgat gtaccgttct ccgcggagtc cgtagaactt cggctcgagg
    86641 aatatccagt ggaagaagag aaaaatgagg aatgtgcccc ctcccatcag gagaacgggt
    86701 gcagactcct caatggccgc aacgacagag ggatcgctgc tgaatgtcgc tgtgagcgca
    86761 ccaaagggac caagagaggg cgttgacatc cagacaatga gccatggaag tactccccgc
    86821 acgataaaaa cggcaatgag gagtccccag agcaggaacc acctccgtgc ccactccttc
    86881 atcgtggaga ggacctcggc attgatgatc gcattgtcaa tgctcgtaat cgtctcaaaa
    86941 agaacgagcc cggcaatgat caggatcgcg gaaaacgggt ccatgggtga ttgttccgcg
    87001 taagttagtc cttattccca aaaaagatta ttatcatatc aattttcttc aaatcaggaa
    87061 actgtacact ggcccccgtc aaagccgttt tccaaaaaag gtacgggggt tttcccccgg
    87121 aaaaaaggtt gttcaattgg aatacgccgg ttttcccagc ttcggctcaa agaccatgtc
    87181 agcttcgacc ctgatggcat gcgagaactt tgcaagcggg atgtccatgg cacagagttc
    87241 ctcgcactgc ccacagttga cgcaggagtc cgatatatgg gcgaacctgc gcaggtggaa
    87301 catggggttt ggcgggacct cacccggttt caccacgaga tcctttgcct tgagcgctcc
    87361 tccggagggg aagcagaccg ggcagttctc gatgcatgag taacacttga tgcaccggga
    87421 ggtctccttc ctgattgtcc cccagagatc cttcgagagt gcctcgaagt ccttcttccg
    87481 ccatttttct ccgagcttga tcatcgctcc ctcgaccttg ccccgcatct cgagaccctt
    87541 tggatcgggt ttctcggtct tgagcgcacc atccttgacc gcacgggcaa ggaggtcggc
    87601 acccttctcg ctgcagacct cgacgaacgt ggccttgccg gccttgtcgc cgatgactcc
    87661 ccagttcccg catgcgaggt ctgcctggcg ggggaccttg tagaggcagc ggcggcagtt
    87721 ggacctgcgg ccgtacccct cgtcttccag gtcatcgatc ttgatgccct tgtggccgcc
    87781 ctcgtactcg atgatgaact ggcccttgtc aatctcttcc ttcgtgaccg tgtcagggtc
    87841 gacgccgaac ttctccttta tcatcttccg ggccatgaca gggctgactg tccccccgca
    87901 gttgacgccg atgaggagga ggttgtttag gtcgatcttt tgcctcctcg cgagttcgtg
    87961 gagggccatg acatcgcagc ctttcaccgt catcgccact ttcatcccct ttgaccgctc
    88021 catgaacttt tgcgcgacct ttgccaggag cagcgtcccg caatggagtg atccggccgt
    88081 atccttcaac tgtccgggat cggtgaccag cacgggaacc gcatcgtaaa catcctggcc
    88141 tttctttaca gcgatgacgg catccacgat cttatgttcg agtgcatact tcaggaggct
    88201 cgtgacagca ccgccgcatt ccgctttctt tgcgatatcc gcgtcactgg tccaggcata
    88261 gaccatgtct ccctttttca cgtcgggttt ccccccaaag agtcccatct tacttccccc
    88321 cctcaatctt cccgatcttc acagcacagg ccttgaactc cgggatcttg gcgatggggt
    88381 cgagtgc
//
LOCUS       DAOOJU010000004        83683 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_310_length_83683_cov_15.577522, whole genome shotgun sequence.
ACCESSION   DAOOJU010000004 DAOOJU010000000
VERSION     DAOOJU010000004.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 83683)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 83683)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83683
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_310_length_83683_cov_15.577522"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            14..1279
                     /gene="hisD"
                     /locus_tag="PK679_01970"
     CDS             14..1279
                     /gene="hisD"
                     /locus_tag="PK679_01970"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HPC54755.1"
                     /translation="MLREKALEEWIANRSAGLTSVRPAVEEIIARVRDGGDAALRELT
                     QKYDGVFRESIRITPEEIENAYSRVDEGFIRSLEDARSRITKFHEIQKPRNLWLEEIE
                     PGIVLGMRMVPLDRVGAYVPGGRAAYASTALMTVIPARVAGVRSVCCCSPPPIAPQSL
                     VAMDIAGADEVFAVGGAQAVAAMALGTESIRPVRKIVGPGNVYVTTAKMLLRDTVEID
                     FPAGPSEIVILADGSARPDFIAADIVAQAEHDPNAACYLVALDPSLPGKVLRELILQV
                     RESPRKEILEKALENTGYTLAASIGEALTIINRAAPEHLSLQINDPMQVLMHAGYAGS
                     VFVGSYSAVACGDYASGTNHVLPTAGYASTYSGLDVLHFCTRSTIQMINQEGLSRIAD
                     TVETLARAEGLEGHARSVRIRRPGERKNA"
     gene            complement(1336..1863)
                     /locus_tag="PK679_01975"
     CDS             complement(1336..1863)
                     /locus_tag="PK679_01975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54756.1"
                     /translation="MGLRTVLSLLVFFLVVTGAATGAISIDATPHDAYIGDRIHINGT
                     IDGKNLIAIFLFVTGPGLDGAGVTLENIHLRAGSGYFTSAFVNPDGSFAYDWDTSFIV
                     GNLVPGKYRIYAVNVPLNLARLTDTDSISVSSTEVTFRRPPPRSLPGFSPCVFFLFFL
                     VTATLGLYRRKEGGP"
     gene            complement(1932..3248)
                     /gene="brxD"
                     /locus_tag="PK679_01980"
     CDS             complement(1932..3248)
                     /gene="brxD"
                     /locus_tag="PK679_01980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system ATP-binding protein BrxD"
                     /protein_id="HPC54757.1"
                     /translation="MEKSMPTGTPDIRGPRKLESQNIINALRRGTVPGSGLERIAVGL
                     DMEEGVIRAQLDYVSQGGGDIKFIRGDYGSGKTFLVARALEIAREKGFVTAHVVISPS
                     APLHKLKELYRQICATLRTREEEHAPKSIIDTWLFGIEERILKVSDQTLPEDVLEKAT
                     LAEIESALAGISELNSSLAAALRTYYRSSNEGDFQTAQSAIGWICAESNVGRDFKQKA
                     GIRGDIDEASAFIFLRGLVRIIVSAGYRGLAVAVDEVETTQSLPRNQREKSYHTLQMI
                     VESLDRGDLSHSYFLFTGTPAFFDGPRGIRTLPPLYDRISVVQPEEGFKNPRQPQIAL
                     ARFDARKLEQVALKVIEIYREAYSDVDRSRVSHRFIRAMISRVTKKFGGRVDVIPRIF
                     LKEFIDVLDKCELYDDYDPWEQYHFDAEHLKGELKDEEEAVMVVEF"
     gene            complement(3217..4881)
                     /locus_tag="PK679_01985"
     CDS             complement(3217..4881)
                     /locus_tag="PK679_01985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54758.1"
                     /translation="MGRLEEAEAFFRDLSHSLPGTSHVHSYLGRILEMKGDDGALAEY
                     ARAVALDPGNLEALRSFASFVLKSGDPKKAVPVFSRLYSHSRRADDARLLARALLMSG
                     RPSEALGVWENVPGGRLAADEEYLAILFACGRFSQVAESALQLFEKTKDPQFARRYLE
                     ALSVTDRQRAREEYPRLVEITGDREIRYDFVLFQKEEGNFGQALAGLGPLLLGERTEG
                     KYLLLECELLALLQRKEEAVRHYRDLLDRELDSMADPAFIQDILSSFRTFLQTHYPFR
                     EAESLLLASLSARTDPFSLLTVARFYEEAGDRGEARSWYYRAYRSDSIRGGPLYAWFC
                     YRNGDNRECEKVMIYVVGTARKVRDLLRVAEVFLQDKDALFRMPRLLERLKARLEEVT
                     EILPSRGMEILATIYLLWGSVSLEKGDCMSCKRSCLAGLDVIPQDAESIRPGDFLALL
                     EECKKRSLSEIPVLLHPERGETGLPEPHDTSLLELDLDENERKILEFLRTRHQATEME
                     LRTLLGSRRVAGIINRIMQKASSKGLVLIEKKGVGKDGEIYAYRNT"
     gene            complement(5041..5751)
                     /locus_tag="PK679_01990"
     CDS             complement(5041..5751)
                     /locus_tag="PK679_01990"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HPC54759.1"
                     /translation="MSGKPTHPPSPAFTLVIPAYNEADRIPLLLSQIAGAEGEFIFVC
                     EGNDETPRLVLEFAGAHPEMTIRCLHRPERMGKGGAIREGMAIASAPLVGYMDADAST
                     SFSQMRDLFSLIDDADGVIGSRWVQGAVLEKPQGLSRRIESRIFNCIVRLLFGLPFRD
                     TQCGAKVFKKSAIDAVIREMVSSGFEFDVELLWRLKRRGFCIREHPIAWRDTSSSNVR
                     GTDGFRMLANLVRLRLGA"
     gene            complement(5819..6046)
                     /locus_tag="PK679_01995"
     CDS             complement(5819..6046)
                     /locus_tag="PK679_01995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54760.1"
                     /translation="MDREEKEMLADLIWLQAVIATELIQITENTSSILRKSPPPRTCI
                     EDHNRLRQHAVAIAERYRPGSGLKEHINGHA"
     gene            6143..6565
                     /locus_tag="PK679_02000"
     CDS             6143..6565
                     /locus_tag="PK679_02000"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HPC54761.1"
                     /translation="MSYLEKVRREGRDANPFFVLMGIDVQEAGTGRAVLRMPVRPDMM
                     NGEGWLQGGIYCALADEAMVLAVYPLLSPGDTIATITETTTFLGGTREGVLFGLGRVV
                     RKGSRVIFAEGEVRSESPEGPVLSRSIATFIVNRTRVQ"
     gene            6909..8510
                     /locus_tag="PK679_02005"
     CDS             6909..8510
                     /locus_tag="PK679_02005"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HPC54762.1"
                     /translation="MKFIVITGGVMSGLGKGITAASVGRILKNRGYAVTAVKIDPYLN
                     IDAGTMNPGQHGEVFVLSDGSEVDLDLGNYERFLDIDLTAAHNITTGKVYRSVIEKER
                     RGDFLGETVQIIPHITDEIKSCIRTAATRQIPGEPPAEICLVEIGGTVGDIESMPFLE
                     AVRQMRGELPPRDTVIIHVTLIPEDTMGDLKTKPTQHSVKALRELGLHADIIVGRSER
                     PIGTHTKRKISAFCDLPIRCVISAATVPDIYQVPMELEKEGLADALTDHLGLEKRTAD
                     TEWYRIVSREYTRRVSVAIVSKYGIEDVYLSIKEALKHAGRSLSTEVVITWLDAERYE
                     PRQLSDFDGILVPGGFGKRGIEGKIGAISWARMNRTPFLGLCLGFQMAVVEYARNVVG
                     WEDATSAEIGEGRHVIAILPEQQEVTGLGGTMRLGDAPVTLKSGTLAEKIYGKREITE
                     RHRHRYEVNPRYIPDLEKSGLVFSGYSGNRMEVLELPDHPFFLATQFHPEFRSRPTRP
                     SPPFLGFVRACSAKNGKPAVGEVKK"
     gene            8507..9424
                     /gene="guaA"
                     /locus_tag="PK679_02010"
     CDS             8507..9424
                     /gene="guaA"
                     /locus_tag="PK679_02010"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HPC54763.1"
                     /translation="MIDPLKFIDQAVEEIRKEAEDRRVVMALSGGVDSSVCAALAARA
                     IGDRLEPIYVDTGLMRKGETERIAQVFGNLRLHIVPAADEFFAALKGVVDPEEKRKVI
                     GERFIRIFEREARRTGARALLQGTIYPDRIESEGGIKSHHNVGGMPLEIAFEKVIEPL
                     RDLYKDEVREIARALGLPPEIQHRMPFPGPGLAVRVIGEVTRERIEVVREANWIVESE
                     IVDQFKPWQCFAALLGLGTGVKGDNRVHGWIVAVRAVNSRDGMTADPLRLPWEVLERV
                     ALRITSEIPDVARVVYDITPKPPATIEYE"
     gene            9479..10636
                     /locus_tag="PK679_02015"
     CDS             9479..10636
                     /locus_tag="PK679_02015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HPC54764.1"
                     /translation="MENQGNFRELDARYYMPAFGREIMIVRGQGSRVWDSSGREYIDC
                     VAGIAVCSTGHCHPGVTGAICEQAKKLIHCSNLYYVPGQAELAEKLVLLTGMAKAFFS
                     NSGAEANEGAIKLARLATGRKKFIAFTHGFHGRTMGSLAVTHKPPIREPFLPLEPRCT
                     FVEYGDLDALRSAMGNDIAGVFVEPIQGEAGVITPPDGFLEGIRDLCDRHGALMIVDE
                     VQTGMGRTGKWLAIQHTDVRPDIVTLAKGIASGFPMGALLAREGLEFHRGEHGSTFAG
                     GPLACAAALATIRVIEEVMPSIPAKAELFRTSLSRFNPRVRGLMIGISVGDKCGDVQK
                     ACAERGLLVNCAADGNLRLVPPLVITPEEIQTACRILTEVLTAKNKLPATL"
     gene            complement(10724..11344)
                     /locus_tag="PK679_02020"
     CDS             complement(10724..11344)
                     /locus_tag="PK679_02020"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HPC54765.1"
                     /translation="MDQNRLYTLPALPYDYRDLAPSISEEQLRIHHTKHHQGYVNGAN
                     AVFEKLEKARKEGSDPDQKAVAKELSFHIGGFLLHVLYWENLAPAGKGGGGSPGGDLA
                     KQIDKDFGSFERFKKEFIAATNSVEGSGWGALSYCKKTGRLLVMQIEKHNVNVFPGFP
                     LLLVVDAWEHAYYIDYKNDRAKYLENIWNIINWKTVGSRFESAKKA"
     gene            11573..12652
                     /locus_tag="PK679_02025"
     CDS             11573..12652
                     /locus_tag="PK679_02025"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HPC54766.1"
                     /translation="MTGKQGFCYDSLVRDCYRSGGYVYAARPGDVTGKTGVTRVARLA
                     SNENPDPPSPRAIEMGKAALCDANRYPGDQVTGLVSALQKYHGPYHFVTGVGMDGVIE
                     TVLRTFVCAGDRVAISTPTFSFYGLAAMGQGADVISVPRENDFSVDPVRFVREAVDAK
                     VSFLCSPNNPTGTVTPASDVAEILEGLSGILFLDNAYVEFCNEEYRPLMKKYGNLVIG
                     RTMSKAFSLAGLRVGYAFVPEWMVPCYTRAMTPFSLNSVSASAAIGALEDADHVTRAR
                     ERVTRLRDFVCRECRFPVHPSGANFVLVDVAPHKGCDVAARLAGRGVIVRSCESFPGL
                     GDHYIRVSIGEEWEMKRFLEEINCL"
     gene            12649..13161
                     /locus_tag="PK679_02030"
     CDS             12649..13161
                     /locus_tag="PK679_02030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase family protein"
                     /protein_id="HPC54767.1"
                     /translation="MMTGITGTPGTGKSSVGKVLSARGHRVTEIADTVTGYVIERDEA
                     RDTLVIDEERWAAEFPHVDGFVVGHLSHLLPCDLVVVLRCEPPVLKERLRRRGYKDAK
                     IRENCEAEALDVILVETLGSHPAEKVLEIDTTHMDPVTCADRIEGFVRGEIPPCSGNI
                     DWSEYLGEEV"
     gene            13158..13754
                     /locus_tag="PK679_02035"
     CDS             13158..13754
                     /locus_tag="PK679_02035"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HPC54768.1"
                     /translation="MTLEFLRPHMSRIMGPFITVSRKAGVSPNTLTVLALFTSACAGT
                     FYWFGHVLFGTLFVALNALFDGLDGALARAEKKESIRGDFLDHVTDRYADILIITGIF
                     AGGAAGWEVGVLALTGVLMSSYLGTQSQAVGMGRFYGGVLGRADRLVLIICAGLLTLV
                     FPGKVFSLSILGWLLLGFGVMGHVTALQRFLYVWRKMP"
     gene            complement(13795..14796)
                     /gene="fen"
                     /locus_tag="PK679_02040"
     CDS             complement(13795..14796)
                     /gene="fen"
                     /locus_tag="PK679_02040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease-1"
                     /protein_id="HPC54769.1"
                     /translation="MGVALRDILADYKDPVTWQDLPGIAAVDAHNALYQFLSIIRQPD
                     GTPLMDQRGRVTSHLSGILFRTANMLEKGIRTVWIYDGTPPSFKQDTVAERRAVREKA
                     GEKWKEALLRGDTEEAYRQARSSSRIDEEIIATSRQLITLLGLPWIQAPSEGEAQAAY
                     MVMRGDARYVVSQDYDTLLFGAPVLVRNLTVSGKRKVRGRTLAIMPERIVLSSVLTGL
                     EISREDLIRVGLLVGTDFNPGIRGVGAKTALRMVRNGEFEQVMRERQPGVDWEEIFHF
                     FAKPPVTEEYSLHWRPPDREGILRMLCDGFDFSPERVENALGGVKTASGQKTLDSWF"
     gene            complement(14828..15142)
                     /locus_tag="PK679_02045"
     CDS             complement(14828..15142)
                     /locus_tag="PK679_02045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54770.1"
                     /translation="MDTQEYVVDALLLVVLVISTLILVFSLNFDLIKSLAAALMMISL
                     GGLIFLVHWKVRRIEKALTQRERMIRMNMEEIATMMSQKYENHVSHIDAIIEEITKRV
                     YR"
     gene            15200..16090
                     /locus_tag="PK679_02050"
     CDS             15200..16090
                     /locus_tag="PK679_02050"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042500 - aspartic endopeptidase activity,
                     intramembrane cleaving [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="presenilin family intramembrane aspartyl
                     protease PSH"
                     /protein_id="HPC54771.1"
                     /translation="MTMKDVLPLAVMPVMLVIIETGALLLSLPLQEAGLAAFEDPSSV
                     ANPFIFIFILLVFTGFLLFLIRFGFRRIIGGIIGISIFFTFVYIFGAVLALLSRDALF
                     VLGGSLLISGIATGVLYLYPEWYVIDCFGILIASGAASIFGISLEIIPVAILLVILAV
                     YDAVSVYKTKHMISLAEGVLETKSPILFVIPRKKGYSYRKEGIGPIGEGERGAFIIGM
                     GDMIMPSILVVSANVFLATAARIGPVTIPALGAMAGSVAGLCLLLVFVKRGRPQAGLP
                     PINGGALAGFLLGYLVSLLV"
     gene            complement(16058..17014)
                     /locus_tag="PK679_02055"
     CDS             complement(16058..17014)
                     /locus_tag="PK679_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HPC54772.1"
                     /translation="MEFESIPTVPTADEILDRSFRRAASRMKLKKNKDRANEEFVRAV
                     SQAIHDRLVRVMQSFPDFDSVPAFYRDIVDIMWGIGKVRKALGSVGWAARWARTHGPG
                     LAYQTRKSEFPARIRKRAVARLASVVHQVEDDLVFLNEVRNILRTLPHVSDEFTVVVA
                     GYPNVGKSSFIRLVSSATPEVAAYPFTTKGIIVGHRVIDRERVQFIDTPGVLDRPAEE
                     RSAIERQALTAMVNLASVILVILDASEQCGYPLEDQFRLLHEIEERVSVPVVPVVNKA
                     DIAYFDGYINMSTETGEGVTEVLEHLLAFRKRSHEERHEVPE"
     gene            17062..17940
                     /locus_tag="PK679_02060"
     CDS             17062..17940
                     /locus_tag="PK679_02060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54773.1"
                     /translation="MDLSLIQKDILITLISLYHKHSHPVKGEEIAEVIRRNPGTVRNQ
                     MQALKAIGLVDGIPGPRGGYNPTAQAYRALNLDISEKEYDVRISRNGEDVPGVKVVEI
                     AFTTLCHPDICRANATIRGSVKAFEIGDQITIGPTPVNKLLIRGEVYGRDEVSQTLLV
                     SIYEMISLPKKPIRYYMSSPLISLKRTDALGDALHLFNAHRIRGAPVIEGDTLYGIVT
                     MSDVARAIEDGIPMTTPVSSVMTTDVVKAPSTVQLFEVIRSFKERDIGRLIVMEGQKP
                     VGILTQSDIIKVFPSL"
     gene            18062..18313
                     /locus_tag="PK679_02065"
     CDS             18062..18313
                     /locus_tag="PK679_02065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HPC54774.1"
                     /translation="MSRVLARSLSKKKIVTNEGKVIGTLKNLVVDFETGQVVDLVIYP
                     DASFDTTGYRTEGDRLYIPFEAVKDIKDYIVVDRYLSRK"
     gene            complement(18295..19008)
                     /locus_tag="PK679_02070"
     CDS             complement(18295..19008)
                     /locus_tag="PK679_02070"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008967 - phosphoglycolate phosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HPC54775.1"
                     /translation="MSSPRRLRGLITDIDGTITDARRRVHTGAIESMRNLVDAGVCVV
                     LASGNTACFMDAFSKMSGTGGIYIGENGGIIRPGWNHDLSVLADGTAPRIALWELVSA
                     CRKRGIGIEHYSLPYRFVDVAFARTLPVSLVEEILRDHPVVVLDTGFAIHIHPPGVSK
                     GAAFTKLAGLLGMETRDFLAIGDGKNDIDMLERAGTGIAVANAHPKLKDHADEVTEKE
                     YGDGFVEALDRYFSHFLDR"
     gene            complement(19164..20135)
                     /gene="radA"
                     /locus_tag="PK679_02075"
     CDS             complement(19164..20135)
                     /gene="radA"
                     /locus_tag="PK679_02075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair and recombination protein RadA"
                     /protein_id="HPC54776.1"
                     /translation="MSSGSLEIEDLPGVGPSTAEKLREAGFLTVESIATASPQELAET
                     AEIGESTAKKMIKAAREMVDLGGFRTGKDVFEQRKEVRKLKMRVPELDALLGGGLETQ
                     AITELYGEFGSGKSQVAHQAAVNVQLPEEEGGLMGSAIFIDTENTFRPERIEQMVLGL
                     GIDADPEEFLENIHVARAHTSDHQMLMMDSAREKAQELKDSERPVRLIIIDSLTAHFR
                     AEYAGRGTLAARQQKLNRHLHDLFRIVDEHNAVGLVTNQVLSNPAVFFGDPTKPIGGN
                     IVGHTATFRIYLRKSKGGKRIARLVDSPNLPEGEAAFMVEESGLKEA"
     gene            complement(20170..21507)
                     /locus_tag="PK679_02080"
     CDS             complement(20170..21507)
                     /locus_tag="PK679_02080"
                     /inference="COORDINATES: protein motif:HMM:NF013499.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="HPC54777.1"
                     /translation="MQFHYALVDDLLSREEFERKVEEKMEACGDLVDEVTAAMMVVQD
                     LGRHHVKIARLGGKQSLFSFFGKVIAKNPVREFERPEGEKGLVASLILGDETGQVRAI
                     LWDEKAAASHDIGIGDVLEVIGRHAGRNPGEITVMAMRPAPVEISGPSEVAPYLAPPR
                     RKDITICILAIGEARKVARKDGSEAEMVEMVVSDGKSISRMVCWVPELMGDMVEGASF
                     RIRGALEKYRKNGPEYSIDEKSTVEPVDGEMAAAPDPLGSIAGKETCSVTGTVISCPP
                     ARSFVTRDGRTSSVRTITITDGTADARVVLWGDNAKIPLLPGEQVGLYLCSVRQAKTG
                     EWEIHAGRGSLIRVPIPSPVAEEEICGDVIVTGGSTYLDTGSDCFIVAGRDLPHGHAI
                     KAQVLRMGKRISILSWEEHVPDREGLLKRCERFTGPVPETDTFTPHGYEDICR"
     gene            complement(21523..22821)
                     /gene="lysA"
                     /locus_tag="PK679_02085"
     CDS             complement(21523..22821)
                     /gene="lysA"
                     /locus_tag="PK679_02085"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HPC54778.1"
                     /translation="MNLPPHLTIREGQLAIGGIDCATLATRYGTPLYVTDQDRIVSLF
                     RSFRDELSSRYPKVKVLYAAKANGNLAILRALAREGAGADVFSPGELRLALSAGMAPG
                     DLLFNGSSKSTDDLSLAVESGVTVSVDSFDELRQLDRISQKKGKETKIAFRVNPAIDV
                     PTHRKIATGLATSKFGIPHDRIRDAYREALACRGVKPVGIHCHIGSQILATEPFAQTA
                     RVMAEIVRDLVRMGVTLEFIDLGGGLGIPYHHYEEERAPTPADYASAIIPPIRDVSTE
                     LGINPALWVEPGRYLVADSTILLVRVNSVKKAHKNFVNVDAGFNLLIRPAMYDSYHEV
                     VVNGRAGMPPSETYTITGPICESGDILASDRRLPPIGAGDLLAILDTGAYGFCMSSQY
                     NCRPRCAEVLIHGGEAALMRRAETIEDLTATMQIPPWQKE"
     gene            complement(22818..23966)
                     /locus_tag="PK679_02090"
     CDS             complement(22818..23966)
                     /locus_tag="PK679_02090"
                     /EC_number="2.6.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LL-diaminopimelate aminotransferase"
                     /protein_id="HPC54779.1"
                     /translation="MYAERMGKLPPYLFARIDELKAKKIREGCDVIDLGVGDPDLATP
                     PHVVEELCRAARDPANHHYPSYAGMPGFRQAVARWYGDRFGVTLDPATEVLALMGSKD
                     GIAHIPEAFVDPGSYVLVPSPGYPVYRTSTLFAEGRVYEMPLRAENGFIPDLDAIPDD
                     IADAARIMFLNYPNNPTAAVTLPGFFERAVEFAREHDIIIVHDNAYSEISYDGYRAPS
                     FLATEGAMDVAIEMHSLSKTFNMTGWRIGMAVGNREILAGLGRVKTNVDSGVFDAVQR
                     AAIAALSGPPDCVAQACSIYRERRDTLVKGLRALGFRVEPPKATFYVWMPVDDCMAFA
                     TRMLDEAGIVVTPGIGFGSGGDGYVRFAFTRSTERIREALERMEDMGL"
     gene            24196..24525
                     /gene="cutA"
                     /locus_tag="PK679_02095"
     CDS             24196..24525
                     /gene="cutA"
                     /locus_tag="PK679_02095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0010038 - response to metal ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="divalent-cation tolerance protein CutA"
                     /protein_id="HPC54780.1"
                     /translation="MSLEEADPVRVILTTAGRDKGPEIARHLVEKRLAACVNTSDVTS
                     CYRWKGEFCCDQEVLLVIKTTLSHVRDALEEIRAIHPYELPEMIVLPVEGGYPPYLAW
                     VREETAP"
     gene            24522..25304
                     /gene="fdhD"
                     /locus_tag="PK679_02100"
     CDS             24522..25304
                     /gene="fdhD"
                     /locus_tag="PK679_02100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009326 - formate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0008863 - formate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0009061 - anaerobic respiration [Evidence
                     IEA];
                     GO_process: GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HPC54781.1"
                     /translation="MTVTTVKGIQVREGRIIEIDDPVIQEDRFSLCINGEFYARIVAS
                     RDQLRELGAGFVVSQGLARDVGDVIVKGDEIDVLASVADGGGREVISTGAIGLSRPFE
                     KVVSPLTLTTRDVYAITEEIETEVWHQTGAVHCSVLSFGGRVVARSSDVGRHNTVDKV
                     IGHAVLNRLDRSQCVIGCTGRQPRDMVTKAAHAGIPIVISRAASTKQGIEAAWEAGIT
                     LVCFSRKGRFTVYSHPGRIRELSGMVLSPPSRAGDMPRQENR"
     gene            25339..25824
                     /locus_tag="PK679_02105"
     CDS             25339..25824
                     /locus_tag="PK679_02105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1890 domain-containing protein"
                     /protein_id="HPC54782.1"
                     /translation="MVFITGQKEEKEAVLVLGCPQVPVQTAVALYLMHGLRRLGVRPI
                     VAGNPAARMLIDVSDPLHHYAGEMVDLDTFIADMAAGRRKHDYYIVFAHNDAGVTYAA
                     TVQSISGKKVIMIIYGENFQAIADRVDFPAEKIMAKAVHNPMPMKKKIDEVLPWLVSN
                     L"
     gene            25803..26081
                     /locus_tag="PK679_02110"
     CDS             25803..26081
                     /locus_tag="PK679_02110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1894 domain-containing protein"
                     /protein_id="HPC54783.1"
                     /translation="MACIESLKYEIILRNATFSECREYIRKNCRELVTVDPGFALFEK
                     PVIGVPPILLGLDGDSITFPYTKPCYGTFLLRTENPEEAARLRSLLKK"
     gene            26192..27844
                     /locus_tag="PK679_02115"
     CDS             26192..27844
                     /locus_tag="PK679_02115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="HPC54784.1"
                     /translation="MTEMSVLVGGRAGDGINSAGLIIAHLLSRIGYRIYMYFDYPSLI
                     KGGHNFAIIRASPEMKGACRREVDFILALNQDTLDLHRDLVRDRTTVICDSSRVKATG
                     ICIPIPGILKEEGAPAVMGNSCIIGAFTRAAGIPWAVLEEVFSRHLRKGLELNLKVAR
                     RGYEMASDHSVIPAGDSPALPILSGNEAIGLGLLHGGLDAYVAYPMTPTSNLLHFLAD
                     IADRAGLLVFHPENEIAVMLMALGLGYAGKKTAVGTSGGGFCLMTEGLSLAGANEVPV
                     VIVLGQRAGPSTGMPTYTGQSDLHFALHAGQGEFPRLVVAPGDPKQAFTWSSLALRLA
                     WRYQVPALILCDKTLCEGYYSFSSPAASVPRIDDALAGTPGPSYRRYLLTDDGVSPLL
                     FPGSPGTVIKVNSYTHDEAGITTEAAEMASLMTEKRIRKGKALENGLLDLPVIAQSGD
                     TSSDKTLVCWGSTAGVCSEVGPELGFRVIQPVVLSPFPAEKFLRATRGTHEMVVVEEN
                     AYGQLEMLLNRFGVRADASVRKYDGRPFAVEELRARLMEVVS"
     gene            27841..28692
                     /locus_tag="PK679_02120"
     CDS             27841..28692
                     /locus_tag="PK679_02120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HPC54785.1"
                     /translation="MSARDFITDAQNTWCPGCGNFVIQFALRDAIRSAIEGGLDPDSI
                     VLVTGIGCHAKMADYLNINSFYSIHGRTVPVATAIKMADPDLQVICCAGDGDAYAEGL
                     DHLVFAAKRNSDITVIVHNNRVYGLTTGQYTPTSPSGFRGRSTPGGTKEEPFNPLEIM
                     LASGATFVARGCTRKRKELEGVIREGIMHRGFSFIDVLQVCASYFNQTDVYDRAVYSL
                     EGHDAADFDAACRKAREWDYNSDSPIAIGTFFRVIRPTLEERLGVPRKKEGTTEETIA
                     RILGERK"
     gene            28822..30069
                     /locus_tag="PK679_02125"
     CDS             28822..30069
                     /locus_tag="PK679_02125"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HPC54786.1"
                     /translation="MVESNLFESVKKNLCSCSADLALDENIEALLKTPRREVSVAIPV
                     RMDTGKIQVFQSFRVQYNDALGPMKGGIRYHPDETIDTIRGLAAIMTWKCALHNLPLG
                     GAKGGVICNPKALSERELERLSRSYVQEMFPYIGPDRDIPAPDVYTDARVMAWMMDEY
                     SRIAGKTTFGSFTGKPVLLGGSEGRGEATALGGWYAIREAMHRRERDFSGITVAVQGF
                     GNVGAHAALLGQELFGARVVAVSDSRGAIYNPDGLAVRDLVEHKKKTGSVIRFPGATN
                     IPGEEILTLPVDVLIPAALENTITSRNADQVRAAVVAEFANGPTSHEADEILFGSGIT
                     VLPDILVNAGGVIVSHFEMIQNFTMDHWDRNKVARKLEGKMVGSFKTVSDLAENNNVS
                     LRKAAYTLAVGRVAGAMRLRGWA"
     gene            30226..30837
                     /locus_tag="PK679_02130"
     CDS             30226..30837
                     /locus_tag="PK679_02130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HPC54787.1"
                     /translation="MVCFMWEFAVSGDLFAWVVLPSLIFMARICDVSLGTLRVIFISR
                     GFKRVAPFVGFFEVIIWLLAIGQVMQNVGNLASYIAYGGGFAAGTYVGMAVEERLSLG
                     NVVIRIITQKDAGQLAGALRKMNVGVTTMDATGATGPVTVLLSVCRRQDLPRVLSCIN
                     RYHPASFYTVEEVKTVKEGIFPRGRGGIHINWRDPHGFFRKGK"
     gene            complement(30925..31572)
                     /locus_tag="PK679_02135"
     CDS             complement(30925..31572)
                     /locus_tag="PK679_02135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2284 domain-containing protein"
                     /protein_id="HPC54788.1"
                     /translation="MNPRLDGEIATLTRLAGEKGALARPIQSRDIVVAEWVRFKCRFG
                     CKGYGKHMSCPPYAPAPAETRKMIAEYSTGLLLRFDGIPGHPDISPDKIPKDFHPFFR
                     DLILWVNGTVHFLEKTAFYHDFPKAFGFGAYPCIYCEHQHCVAEEQPGTVDESIRRMC
                     RHMDLVRPSMEAAGIDVFSTARNAGWELHVVPCRNLEYGMIEHGNIISIGLVMLE"
     gene            31740..32558
                     /locus_tag="PK679_02140"
     CDS             31740..32558
                     /locus_tag="PK679_02140"
                     /inference="COORDINATES: protein motif:HMM:NF014573.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC54789.1"
                     /translation="MQEEDLGDIYPGMVRYSVELWEKEGLVAVFRTNSFEYAPTMTYG
                     AREAAERVFSSWERDLAGDIEGFLENNSLREPIPYQSPPETPGVVVIQGSPRPGGNCS
                     ILASWTADEAQQLGKPVCVVFPHDLDIHPCIGCYQCYNTGTCVYEDDMNSIIPAVEKC
                     RLLVVCTPVYTNTVPAGTKALLDRFQALHASRTLGRRPSRGTRGLLLSVAGRKGKENF
                     TCVSRVVGAFFSLVGISAEKPVLLDGMDETRDIRVIPGLETRVRDAVRTALRKD"
     gene            complement(32657..33340)
                     /locus_tag="PK679_02145"
     CDS             complement(32657..33340)
                     /locus_tag="PK679_02145"
                     /inference="COORDINATES: protein motif:HMM:NF014626.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HPC54790.1"
                     /translation="MCGRFTLALTVGLGERFGVDDTGLSLSPRFNIAPSQQVPIIYAT
                     HTGERVIRMMTWGLVPSWTRDLTGARPIINARADTLSERPSFHGPLARHRCLVPATGF
                     YEWQKSGTQKVPVYIRRKDQALFAFAGLFDILKGRDPPLWTFTIITTEPNALVARFHD
                     RMPAILQPRDEARWIAPGPIGEGERKAILSPCPDDILEAYPVSKAVNDPQQDGPHLIQ
                     RSGDRTLDL"
     gene            complement(33313..34050)
                     /locus_tag="PK679_02150"
     CDS             complement(33313..34050)
                     /locus_tag="PK679_02150"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HPC54791.1"
                     /translation="MSATTYGNRVRAVILDMDNTLFDLVEAKYAACMAITREAGCGKA
                     EDLFSYFLRKEKGFEDPQNVRDFLEDHGMTDPDLISRCTRMYREVKLARIHPYPGVQK
                     TLGALREQGYPLALVTDAHRPEAVSRLEKTDLIGLFDHIVTHEATWQKKPSPVPFQYA
                     LKLLGVPPREVIAVGDSPRRDIAPCRQMGMITVYARYGDRFSRRGDSGGAHFAIDSLG
                     QVLPIIDSIRIQEMEQGYPCAADSRLP"
     gene            34177..35553
                     /locus_tag="PK679_02155"
     CDS             34177..35553
                     /locus_tag="PK679_02155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC54792.1"
                     /translation="MLLHKIRSEGLSHYSYFVADGGQAAVIDPRRDCQVYLDLASSTA
                     SRITHIFETHRNEDYVSGSCELAERTGAAIYHGAALDFSFGRPVSEGDRFRIGRLELA
                     VLATPGHTAESISLVLRDLSIPGDPLMVFTGDALFAGDVGRTDLFGPKKAEWAAGTLY
                     DAIHEKILPLGDGVVILPAHGAGSVCGGDIADLEFTTIGYERTHNPCFLLDRETFIAG
                     KKAEHHYRPPYFSMMEKLNRSGPPVLSHLPRPVPLDPQTLAEKKKAGAQILDTRSPEA
                     FGGGHIPGSISLWRDGIPAFAGWVLSYDHPVVIVDDCPDGLDSALRRLVRLGYDAIGG
                     YLAGGFAAWARSGREIRRLETWSAAMLRDALEKERFILLDVRDRKNREAMGFIMGSRH
                     IYVGEVLPRLAEIPRNQKVVVYCDAGFKGSLAASLLLAAGFDHVVNVIGGFSGWKAAG
                     YPVEKKST"
     gene            35627..36103
                     /locus_tag="PK679_02160"
     CDS             35627..36103
                     /locus_tag="PK679_02160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HPC54793.1"
                     /translation="MEIVKIPRMEKKEYDTLIEKGYICRIAFQGEKYPYIAPFLYVFD
                     GRFLYFLSTKYGKKLEYFRKSPYVAVEVEKYTKDLSSYTFVSMQGYLEEVTDSIDKKV
                     IRKQFVDLIKERRLSNNILAALGHSPQDPPEAIAKEERSLVWKLTGVKDMVALKNL"
     gene            complement(36129..38264)
                     /locus_tag="PK679_02165"
     CDS             complement(36129..38264)
                     /locus_tag="PK679_02165"
                     /inference="COORDINATES: protein motif:HMM:NF015168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HPC54794.1"
                     /translation="MAEEGRKAGPGDPGQNRLIKEVSPYLRQHAFDPVDWYPWGDEAF
                     VRAREEDKPIFLSIGYATCHWCHVMREESFSDPEVGRFLNDNFVCIKLDREERPDLDQ
                     YYMDACIAFTGRGGWPLSIFLTPGGVPFFATSYIPRTRTGGNYGILEVLAAIAAYWKE
                     HRDDALSLARDISENIVHARDHAYSGPLPAGTAGMVYDHLVSIHDSKNGGFGPPPRFP
                     LFHLHLFLLRYGIIHRTTAPIDLSCHTLLSMARGGVYDQLGGGFHRYATDERWLVPHF
                     EKMLYDQALAALAYSEAYTLTGNAVLGNVARGCMEYICRDLQAPDGGFYAGEDADSGG
                     GEGLFYTWTRDEIESVLSPEENRIASSVFSLNCIDTPGSAGGTSAREAGVLSRARQPA
                     DAARLLGMAPGDVERVLETMKEKLLSARNTRPHPPRDTLVLADWNGLAISALSVASRT
                     LGDPAFLAAARRAAGFVLGQMRSPDGGIYHRWMAGDAAIQGMSADYASVIMGLLDLFL
                     ATREPTFLSAAIELEDYHFQNFWDKDKGGYYWTRDDQKDVPVRQKEFLDGSIPSSNSL
                     SFSNLVRLHILTGETSYMERAGQVAGYYPPLVRQYPSSCTMFFAGHLVTEGRAGTVVV
                     TGDETDPLYVRMLGILDRNYTPFILPVALGRKPDAGEICRLLPWCALLAGENRGPRAH
                     ACLGQSCQNPITDAGSLESLLKGYLPGKQ"
     gene            38399..41065
                     /gene="mutS"
                     /locus_tag="PK679_02170"
     CDS             38399..41065
                     /gene="mutS"
                     /locus_tag="PK679_02170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HPC54795.1"
                     /translation="MSRDDQTPGQASGTRLTPAMAQYQELKARYPDTILLFHIGDFYE
                     TFGDDARTLSRELDIVLTSRSRDKEKNPVPLAGVPCHAVEGYIARLIAKGYRVAVADQ
                     VEDPREAKGIVRREVVRVITPGMVMDETLLESPAANYLAAIAPKEKKRPGGMAFLDIT
                     TGEFFCMSLPVENEIAAVSDEIARYAPRECIVPENLQPELLEHLSGKPLTVSRVPASW
                     YDPESARVFLCNHLGVSSLEGFGLAGMDGAVVAAAAALMYARETQKQDLRQVTTLSVR
                     HVRDFCLLDAVTQRNLEILRGIRGTGKEGTLISVLDRTATPMGSRLMREWLCAPLLSC
                     EAINARLDAVEFMVRKAAVRMELAQVLKRCGDLGRISGRIAFGNVCPRDLKSAADALE
                     VVPRIVGILGTGTGEGAPELIAGACGMIPDLGWVKDLIGRAIVDDPPASVRNGGVIRP
                     GFCPELDSLRDLSSSGRDWIADLQQREREKTGIRSLKIGYNSVFGYYIEVTRPNLHLV
                     PPHYQRKQTTSSGERFTIPELAEKEALISSADERRLTLEQEVYQDLVRQLQAAVPGLQ
                     SMARGLAILDVVCSLANVAVSNNYCRPVVDNSTHLLIRGGRHPVVEEGMQGKFVPNDL
                     EMSGERDQILIITGANMAGKSTYMRAAALIVIMAQAGSFVPAEYARVGIVDRVFSRVG
                     AFDDLASGQSTFMVEMLELANILNNVTGKSLVILDEIGRGTSTLDGLCIARAVLEYLH
                     GGRSHGPRTLFATHFHEIVSMEGELPRVKNFHFAVRETGKEVVFLRKLIPGATDRSYG
                     IHVASLAGVPRQVTERARALLEEETRGGGSGREGKPKRYTQMLLLDIAPEVQSHPVLE
                     TLKNLNLDDMTPLSALSTLYELQKKARGPGGR"
     gene            41071..42873
                     /gene="mutL"
                     /locus_tag="PK679_02175"
     CDS             41071..42873
                     /gene="mutL"
                     /locus_tag="PK679_02175"
                     /inference="COORDINATES: protein motif:HMM:TIGR00585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HPC54796.1"
                     /translation="MEEQGTGGKIRLLDKETISRISAGEVIERPASVVKELVENAIDA
                     GARRIEVEITSKGGKIAGIRVTDDGCGMTPRDAELACVRHATSKIASLDDLMEVSSLG
                     FRGEALASIAAVSRLTLISRAGKEALAGIRILYEGGAPVLREECGCPPGTTVEVRDLF
                     FNTPVRKKFMRSLAAEMAYITGTMERIILSHPGIFFRVLHNKRTLISSPGGTVRDAVL
                     HLFGTDCEKSLIPVHFSGRSVRVEGVVSRPAFFRQNPYQIFVSVNGRPVQSRPLALAV
                     REGYGTLLPADRFPMAVLDIMLDPELVDVNVHPTKREVRIAREQDVRREISLAVKAAL
                     ESEVLIPEVEDASRIARQSTLIAPSHGTAYDSVSLSPGTVSEPGVPAFTGQVRMEKQS
                     ELGVEEDTEERSREGFLPEMDVLGQLDDTYILASFRGGEDLILVDQHAAHERILFDQL
                     TAGDAIQSQSQELLVPVILDLSPREQSILPDIVPVLCEAGFTIEEFGGGSYAVRAIPV
                     VLGRQVDPGAVRELLSAILAGNEKHGPSRADAIRKVVACRGAIKAGTPLSREQCRTLL
                     NELRQTSHPFSCPHGRPTMVIFRKRDLDGLFLRS"
     gene            42963..43307
                     /locus_tag="PK679_02180"
     CDS             42963..43307
                     /locus_tag="PK679_02180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54797.1"
                     /translation="MPDLHHTPSIAAVCVILCGLVLASPVAAEFLGGSLISSSTSISG
                     NVVINETVSVKKITYTDGFPKIQEWTFQESVVNPGARTWTTEMTFVPKDTGTKFSFSR
                     TGNLFSPFSFRI"
     gene            43474..46140
                     /locus_tag="PK679_02185"
     CDS             43474..46140
                     /locus_tag="PK679_02185"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC54798.1"
                     /translation="MISVLYVDDEEPLLHLGKTFLERYSPDIRVDTAPSAQKALEMLL
                     SGKYDAIVSDYQMPGMDGIALLREIRSGGSNIPFIVFTGKGREEIVIQAINYGADYYL
                     QKGGDPKSQFAELIHQIHQAVAKRRAEEELRESRKRLADIIDFLPDAVFAIDREGRVI
                     AWNRAIEEMTGVSADEMIGKGDREYSIPFYGDRRPILIDYILSQDETIPNHYSLITRD
                     RDVLIAETDLPHPRGERRILFGKASPLYDENGKIVGAIESIRDITDYKWSERRLTEAL
                     RQVSGAEERIRASLSELKQREELLRESEKKYETLFHEAADIIILIDTEGRILDFNRKF
                     MEESQRDPEEVTGKDIFSTGLIAPEYHALVAGYLEGIREGRTIPIFEIEGIQKSGKRI
                     PYEVRVSPLVLEGRVTAVQAILRNLTERKAAENALRRSEALYRSVVDNIQDVFYRADM
                     DGILTMASPSFARLLGYSSVDECIGKDLARDFYLDPKEREKFLAALEDAGEVFDYEVT
                     LKRKDGTPVIVSSNSHYFYDEQGKRAGVEGIFRDITENKRIIAALRESETFYRALFEN
                     TGTATVVIEEDTTISRVNTQFEKLTGYPREEVEGKKSWTEFVVEEDRGWMLDQHRKRR
                     VDPSGAPTHYEFRVKNRNGEVRFVFLTIVIIPGTKKSIASVLDITDVRNAEAAVRRLN
                     KNLNLLYGVTIHDIANKVTAVQGYLELLQEMNRDTSIDDLIRNALSAIGNIARHIQFA
                     RVYQDLGIKEPLWQNLGAVISRHAPGDVPVSISCSGIAVYADQMLEHVFANLFDNSLR
                     HGGNVTSISVECSKSGNDLVVRFRDNGKGIAEADKEKIFEKGYGDHTGYGLFLTREIL
                     AITGISIRECGVPGEGAVFEIIVPGGAWRYNP"
     gene            46137..47504
                     /locus_tag="PK679_02190"
     CDS             46137..47504
                     /locus_tag="PK679_02190"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HPC54799.1"
                     /translation="MIDRSRIREIRALPAGKGKYVLYWMQSSVRSGGNMALAYALAIA
                     RTRDLPVVTCFCIDPSYPEANLRHFTFLAEGILSAGKRLSRRKIPLVLRRGDPVKEIS
                     DLARDAALVVTDRGYLSYHRRCREALARETGSPFTVVEDNAIVPVESASQKEEWSAGT
                     FRRKIGGHVPFFFDLPADAVSVRKPPDIDGIPYRDVKTLIHSGIDSTVGPSPLFRGGE
                     DEARRRLEIFIKDKLPIYPSRRNDPSRDVLSHLSPYLHFGNISPLECASRVLETQGQG
                     TGEFLDQLIVRRELAINFVHYNPRYDSFQGLPSWVLETLAHHARDLREYTYTARELER
                     AATHDPYWNACQNELVITGKMHGYMRMYWAKKILEWTRSPEEAFSLALVLNNRYELDG
                     RDPSSYAGIAWCFGKHDRPWPERPVFGKVRYMNAAGLARKFRIDGYVQRVEALIEKYG
                     IPGRE"
     gene            47482..48327
                     /locus_tag="PK679_02195"
     CDS             47482..48327
                     /locus_tag="PK679_02195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HPC54800.1"
                     /translation="MEYPEGNEACALSPEEIARFREAVYSHYSKHRRRFPWRETTDPY
                     CILVSEVMLQQTGVERVMVHYPPFTSSFPGFSPLAEAPLADVLRAWKGLGYNRRALNL
                     HKTARIVTSEHGGMLPAEEKDLLSLPGIGKATAASIRAFAYNMPSVFIETNIRRLFLH
                     WFFPSGDRIPDSRILPLVRATLDRENPRDWYYALMDFGARLRSVVPDPNQRSAHYHRQ
                     APFRGSDREIRGRIISVLLRSGCVDQSDLPAEVEAEGDRVRAICDRMAAEGLIIKEGG
                     RFRLP"
     gene            complement(48362..48541)
                     /locus_tag="PK679_02200"
     CDS             complement(48362..48541)
                     /locus_tag="PK679_02200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54801.1"
                     /translation="MEKSAKKQISLLCFGAGFILLLIQDLKGFSTINLGFSWPWAIMF
                     YTGLLLILIGYYLRG"
     gene            complement(48620..49216)
                     /locus_tag="PK679_02205"
     CDS             complement(48620..49216)
                     /locus_tag="PK679_02205"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HPC54802.1"
                     /translation="MKIVGVGCGPGMLTAQAIRELSEARLVYGSGRAIDLAREFIRPD
                     AVVHEIEDYRSLRDLPSGAVVLSTGDPMLAGLGYLPGEVIPGISSLQLALARLHIPMQ
                     DVSVVVAHGRNHGRALADLHSEVERGKTVFLIADPGFDVGFCAATLLDIPGEVAIILC
                     EDLGYPGERIESGTRTNPPSPRSDLFSLIIRPEGKNRG"
     gene            complement(49213..50235)
                     /locus_tag="PK679_02210"
     CDS             complement(49213..50235)
                     /locus_tag="PK679_02210"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HPC54803.1"
                     /translation="MQKSEPLVDPVTGFSYPKAWVAACRDREQLALAASGLGVLTASG
                     KVLRRGFTTGTTAAAACKAAVLSLKYPVDSVSVRIPCGISLNVPVQGSGGRAGASKFA
                     GDYPGDATAGLVFVAEAEIRDGGVTLETGEGIGRFSRDTPRGRSGEPAISPPALQEIM
                     EAITEGMEMTGIPGVAITLTVPDGKDIATKTLNPRLGILGGISVLGTTGLVEPWDDHM
                     AGSVKERVAAAGRVVITTGRLGLRYSRLHFPDHEIVLAGSRIGEALGAARGEIILSGL
                     PGLVLKFLFPGILEGTGCLTVEELAQTPVFPEKMEEAFAIARTKYPFLRVVILSRNGE
                     IVGDSG"
     gene            complement(50222..50902)
                     /locus_tag="PK679_02215"
     CDS             complement(50222..50902)
                     /locus_tag="PK679_02215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-8X methylmutase"
                     /protein_id="HPC54804.1"
                     /translation="MTRQSSPRGDTRKNTYTDLGAIPGEALRISEKSRKIARREIGNE
                     TPEDRIRQRCSIAVGDLAMAGLLRFAHDPVAAGLSALGRSAPLIADIRMVQVGIQKKG
                     HGSRVICALDHAGKAHAEGITRTRAGILALRDEIDGAIVVIGNAPSALLSLCDLIEEG
                     CRPALVVGTPVGFVNAAESKERLRSLPVPSITNVGTRGGTPVAVAAINEIITMFAENH
                     PDRGHAEE"
     gene            complement(50850..51632)
                     /gene="cobJ"
                     /locus_tag="PK679_02220"
     CDS             complement(50850..51632)
                     /gene="cobJ"
                     /locus_tag="PK679_02220"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030789 - precorrin-3B
                     C17-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HPC54805.1"
                     /translation="MPLPGEERGVLYVVGCGPGPLDQMTGRAVAALKEAEYVLGNESY
                     LAPLAPLLEGKKVIRSSMGKEVERAKLAVELAEKCIVAMVSGGDPGVYGMAGIVLEVA
                     QRSDPPVKVVVIPGVTAATAAASLLGSPLSGDFAVVSLSDLLTPLGIIEERLRCAFAM
                     GVPVVLYNPRSHGRPHNFARAVEIALRFRDPATPVGIVKNAYREGEEIIVTTLAGVTD
                     YEEAIDMHSTVIVGGVETRIGKVGENDKTIITPRGYQKKYVY"
     gene            complement(51616..52485)
                     /gene="cbiG"
                     /locus_tag="PK679_02225"
     CDS             complement(51616..52485)
                     /gene="cbiG"
                     /locus_tag="PK679_02225"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HPC54806.1"
                     /translation="MKGSVIALERFLSPARRIAEYLDGNLVVFSREAFASAFRDSPWI
                     VAVMATGIATRAIAPLLRDKWHDPAVVVVDPDLSFAIPLIGGHHGANDLARRLAGLGA
                     VPVITTATDRSGKESVEAAATRAGCSILNRESTLPVNAAILDGEVPIYTVSGPSMVIA
                     GPRVAILFRKGEYSVGIGCRRGTGAESVREALEKAFEMAGIEKEDVGIYASTVKKAHE
                     QGIIGGVRALGGTIVFLEDSVLAAYPPASPSRAGSVGLAGVAEPAALAVSEKKELIMK
                     KTVFGGVTVAIAR"
     gene            complement(52482..53198)
                     /gene="cobM"
                     /locus_tag="PK679_02230"
     CDS             complement(52482..53198)
                     /gene="cobM"
                     /locus_tag="PK679_02230"
                     /EC_number="2.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046026 - precorrin-4
                     C11-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-4 C(11)-methyltransferase"
                     /protein_id="HPC54807.1"
                     /translation="MARVYFVGAGPGDPGLITVRGRDLLSRADVLVYTGSLVNPRLVE
                     DCPAHLKVDSHGMRLEDIGQLLVRHARAGSTVVRLHSGDPSLYGAIVEQMQLLSEAGV
                     DFEVIPGVSSLFAAAAALKTQLTLGGVAESLIVTRPAGSTLEHDEIAELSEHRATMVF
                     FLGTAHLEEITSRVRCPPDTPAAVVYHASWEDQRIVRGTVADIAEKAREAGIERTALL
                     IIGGVLEPASSGHRRSHLYS"
     gene            complement(53200..53805)
                     /locus_tag="PK679_02235"
     CDS             complement(53200..53805)
                     /locus_tag="PK679_02235"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HPC54808.1"
                     /translation="MLIGLGLGPGDPELLTLRAVRLLREADAVFVPGRLAHALVSPYR
                     DAEILDFPMTEDPAQIRLCMERNAEKIAPVASSGSAVLALIGDPNFFSTFTRLCQVME
                     EKYPSIVCRTEPGISAITAFAAVAGVSLSGGFCVSDGTEQRYRVLLKVRRPREAASAL
                     GREGFRRFVLVEKMYLPDMHVYRDGDLPETCDYLSVLYAER"
     gene            complement(53799..54329)
                     /gene="cbiT"
                     /locus_tag="PK679_02240"
     CDS             complement(53799..54329)
                     /gene="cbiT"
                     /locus_tag="PK679_02240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046025 - precorrin-6Y
                     C5,15-methyltransferase (decarboxylating) activity
                     [Evidence IEA];
                     GO_process: GO:0046140 - corrin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6Y C5,15-methyltransferase
                     (decarboxylating) subunit CbiT"
                     /protein_id="HPC54809.1"
                     /translation="MGLSGGPTKDEVMAVALAKLDLQPGDRFMDIGCGTGKIAIHAAR
                     QVASVYAIDTRREAIEFARGEAERAGVRNIEFLEGNAADLIPGLPRADAAFLGGSRDM
                     DRILPLLAGLKVRSIVVNAVKIDTVAAAIPLMHELGIFREAVLVQVSHANPIGTGYMW
                     KPANPVAIIVGGTPPC"
     gene            complement(54540..55292)
                     /gene="cobA"
                     /locus_tag="PK679_02245"
     CDS             complement(54540..55292)
                     /gene="cobA"
                     /locus_tag="PK679_02245"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HPC54810.1"
                     /translation="MKGKVYLVGSGPGGKALLTLRAQQVLEEADVILYDQLPGPEILA
                     GLPERAEKIDCGKFGGQHTLEQDEIEEIMVARALEGKKVVRLKGGDPFLFGRGGEELG
                     VLRERGIPVELVPGITSAIAVPGAVGIPVTHRKYASSVTILTGHEDPEKDGSAIDWEN
                     LAGNRGTLVILMGVRNLPAIAENLVSHGKDPGTPVAIIERGMRPDQRVTTGTLATIAG
                     IARERRVRPPAVIVIGDVVRLYREGEPGLVPL"
     gene            complement(55289..56173)
                     /gene="hemC"
                     /locus_tag="PK679_02250"
     CDS             complement(55289..56173)
                     /gene="hemC"
                     /locus_tag="PK679_02250"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HPC54811.1"
                     /translation="MSLLIGTRGSALALAQADRVIALLEKNGIEAEKVIISTLGDTVT
                     GVPLHEIGGQGVFVRALDDALLQGGIDAAVHSAKDIPARRPQGLVTCAVLERDSPADF
                     LVHTIPFPKIRVVGTSSTRRRAQLLKHYPYLEIVPLRGNVDTRLRKLKEGQFDAIVLA
                     EAGLQRLGLTLPGTRLPPETFVPSPNQGTIAVVSREGETAEMLADALDHPQTRRDIGF
                     ERVAMEEIGGGCFTPLGIYCDRGHMHAEVLSLAGDRSVRRDCMCADERSVLDLARELK
                     AKAAPLIGEAYAKLGLKE"
     gene            complement(56161..57405)
                     /locus_tag="PK679_02255"
     CDS             complement(56161..57405)
                     /locus_tag="PK679_02255"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA];
                     GO_process: GO:0006782 - protoporphyrinogen IX
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HPC54812.1"
                     /translation="MKSSDYFARARTLIPGGVSSPVRAIAPYPFYTRRASGSRLFTVD
                     DHELIDCCMGYGPLLLGHAHPQIEAAIRRQVGDGWLYGTPTPLEVRFAEMLCRDHPGM
                     NMVRFVSSGSEATMAAIRLARGFSGKKDIVKVEGGFHGAHDSVLVKAGSGATTLGIPD
                     SAGVLPDVASHTLQVPYNDPDALEDLLSRHKDVAAFIIEPVMGNIGPILPQDGYLRDV
                     REITRANDVLLIFDEVICGYRVGIGGAQKRWGVVPDITTLGKIIGGGLPIGAFGGRRE
                     IMAMVAPAGPVYNAGTFSGNPLSLAAGIATVEWIHDHPALYRDLGEKTRAIGEAVSDT
                     GRGSFVCLGSMFKFFFRNAEPRNYREAKECDTGAFKQFWEKMLASGIFLPPSQFETNF
                     LSVAHTDGDVETISTAYRQCLS"
     gene            complement(57392..58375)
                     /gene="hemB"
                     /locus_tag="PK679_02260"
     CDS             complement(57392..58375)
                     /gene="hemB"
                     /locus_tag="PK679_02260"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HPC54813.1"
                     /translation="MFPKRRMRRLRAPVIRPLLAETALSKNDLVAPVFIDETAQKQKS
                     IESMPGQVRYPLAEAGTVARDLWDAGIRALLLFGIPRKKDEQASCAFDPNGIVQKAVR
                     AVKREVPEMVVITDVCACEYTDHGHCGIVGVTRHGPDLLNDPSLDLMDRIALSHAQSG
                     ADIVAPSCMLDGVVQSIRAALDREGHSDVAIMSYSTKFSSALYGPFRDAADSGFRFGD
                     RSTYQVPPGNSREAVLESMLDFDEGADILMVKPAGFYLDILAEVRTLGIPVAAFQVSG
                     EYAMIKAAAARGWLDEKEVALETLTCIKRAGADLIITYFARDVAGWLDEEQ"
     gene            complement(58354..59640)
                     /gene="hemA"
                     /locus_tag="PK679_02265"
     CDS             complement(58354..59640)
                     /gene="hemA"
                     /locus_tag="PK679_02265"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008883 - glutamyl-tRNA reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HPC54814.1"
                     /translation="MSATEEASLQVPVAIAGISHHTATADVLERMRFPDEKEFLKEAR
                     ERFRGIVLLQTCNRVEVLVHGDPESLSSFLESAGWKEYTLLAGTDALRHLLELACGID
                     SMIVGEDQILGQMKSALMQAMEAGCTSPILELCINKAVHAGIEARRRTRINRGAVSVG
                     SAAVRLAEERLGTLEGKHILVIGSGEMGGLVARALAVKNLTAIYVANRTYSRAKTLAE
                     KIGGRAIRFEDLPRYMILSDVVISCTSAPHPVIHCDQLERVMAARCWPHETRPRPLIV
                     IDIAQPRDVEEGAGDIRGVSLFSIDDLREVNERTMDSRRAEAARVREFIDGELVRFVR
                     LLNSHAADDVLGTLHTWAEAIRVRERDRAIARLGNPDERTCGIVDDLSRVLARKLLSD
                     VTMSVRLCAEEGDLERAEALVAAIVRGEKPCSRKEE"
     gene            complement(59637..60260)
                     /locus_tag="PK679_02270"
     CDS             complement(59637..60260)
                     /locus_tag="PK679_02270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HPC54815.1"
                     /translation="MIPLLVDFSKKKVAIFGGGDVGARKAAFFAQEGSVVVYSRSFSP
                     ALTDLPVTRITIDLGGIPDEKLLSLLEGFFCAVAATPDPGLNNRIGEACRRKGILFNN
                     AEGERGDFLIPSVVRGEHFILAVSTEGASPAIPRFIREHLEETFPYLDRMVSVQERLR
                     AYLRECQPDPQVRREILWNVLKDRDVWAALRKGETYTWSLIAGRYLA"
     gene            60532..60603
                     /locus_tag="PK679_02275"
     tRNA            60532..60603
                     /locus_tag="PK679_02275"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60565..60567,aa:Gly,seq:gcc)
     gene            complement(60676..61092)
                     /locus_tag="PK679_02280"
     CDS             complement(60676..61092)
                     /locus_tag="PK679_02280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC54816.1"
                     /translation="MCTDTGTICICGLGGIFSTISKKWALLIINRLGMRGRLRFGDLM
                     DELAGISPKTLSDTLKELQEENLVGRESFAEVPPRVEYFLTEEGKGLREAIIPLLEWA
                     SRRDSEKVSSCTVPCRKSPCFAKKGKGKRGTGTASE"
     gene            complement(61128..61409)
                     /locus_tag="PK679_02285"
     CDS             complement(61128..61409)
                     /locus_tag="PK679_02285"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54817.1"
                     /translation="MSPESVLFNIGKKIEYPPEGSLLSSFTFERCNPPVKSLDPGEVY
                     TLELLTDLHLIPYIRGAGVAAPPLCMVNIVAARFTHRKSPPFFQPKLSF"
     gene            61483..62412
                     /locus_tag="PK679_02290"
     CDS             61483..62412
                     /locus_tag="PK679_02290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC54818.1"
                     /translation="MTDIISAQDLVKTFGRNRAVDGVSFAVGEGEIFGFLGPNGAGKT
                     TTTRMLTGVIPPDSGTATVLGHDIRKKPVLAKQGFGVVPETSNAYTDLSAWQNMMLMG
                     ELYGLPRRLAEKRASDLLVTVGLLGNKEQKVQAYSKGMKQRLILAMALVHDPKVLFLD
                     EPTGGLDVQSTQMILSLLRDKNREGMTIFLTTHNMEEANRLCHRVAIIRHGKIVAIDA
                     PEKLKMAIDRVHRIEVSFDRGVPGEALGEVSGVIAVNRIGDKYRLDVLSRDTAIRSLV
                     AFAASNNLQIVTLNTLAPTLDDAFLRLTQEGGS"
     gene            62409..63164
                     /locus_tag="PK679_02295"
     CDS             62409..63164
                     /locus_tag="PK679_02295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC54819.1"
                     /translation="MNPESLPEQARRAWVVAKKDIRIYYLKGPVLIFGVFMPVFLFLA
                     FYMGGRDLPLAFLIPGLVGMTLFFSATAVSPAIFPWEGSAKTLERLAACPISIEAIVL
                     GDMIASALFGIGITLVTVLIGVGVGLPVLHVDILFIALFLGACCFSALGTLLAVPPTN
                     VPSNIMMLSSLLKFPLVFISGIFVPLAEMPRWGLPLAAISPLTYFCDLARYCFSGAHY
                     FPITLDIGLLALFAVVLSIATMYFHRKTMPRRL"
     gene            63414..63674
                     /locus_tag="PK679_02300"
     CDS             63414..63674
                     /locus_tag="PK679_02300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016730 - oxidoreductase activity, acting
                     on iron-sulfur proteins as donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-thioredoxin reductase catalytic
                     domain-containing protein"
                     /protein_id="HPC54820.1"
                     /translation="MRSWTRAYASRHGWILNPDKRALDIVIRGLTRNCRKFGHPYCPC
                     RLRSGNPEKDQDIICPCIFHKDEVRDEGNCHCRLFFRPDKAE"
     gene            63885..65384
                     /locus_tag="PK679_02305"
     CDS             63885..65384
                     /locus_tag="PK679_02305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2193 domain-containing protein"
                     /protein_id="HPC54821.1"
                     /translation="MSELYKKMVHEAMAAQRADVETVRKKRGQSFVIDDAKAYLDAVK
                     LMKPIGEQSKAVFSLHVESVKAHFDVLEKLTRTVRPEDDPFVEHYQTPVVMEILYDQD
                     PAFRKSADAFVRAIGKAEALIGKESARRYAGFYGPTCVVDFALIPGSTSNVVNQILQK
                     TDIPAAHKQAILASKSWGMNTSYGIGEVFAHEIEKGATLADAVKAEIKMLQSVYDHPV
                     ETQVRLMDDAGMSSFDCRKYMSGYRKKMEAPVRAAIDDGIHYGNIVTIPAYCVGDIAH
                     HIAQSTFNMCKDDVIMATIDAATEVMDKNLNAAIPKFKNEYDVLSVATGASACAAEYL
                     LELDGFNAIMVVDLLTKRWHNYVQLYPRRGAAAELHNCDFMDMIYRGWKYIDKARRAQ
                     NGRPGMLKPKVGSFEIDLSPIHENEVLMNPQRYAYPACAITVRASAMLRLADYPCLLT
                     SEPVTATLMTNIIALHKEVAAAPARICKDCASAALMDFRHCYCQWKEAV"
     gene            65411..65620
                     /locus_tag="PK679_02310"
     CDS             65411..65620
                     /locus_tag="PK679_02310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2180 family protein"
                     /protein_id="HPC54822.1"
                     /translation="MKCYVCAQEGRSSDAVAVCIVCGMGLCREHAMREELEMWEGGYP
                     FPAKKVKAKIPRILCPECYHALKGK"
     gene            65626..66381
                     /locus_tag="PK679_02315"
     CDS             65626..66381
                     /locus_tag="PK679_02315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HPC54823.1"
                     /translation="MGDLGKRCIAELAGTALLVYFGAGAAAITLMIARGTNTSTLFNI
                     GIGALGGLGDWFAIGMAFAIVIAAVIYSMGRVSGAHINPAVTIALWATKRFSTGETGA
                     YIVSQLIGAALGSLLFTASAGMDAVTIGGLGATAPFPGIGYGQAILAEAIGTFVLMVV
                     IMGIAVDKRAPPGFAGLVIGLTVGGVITTIGNITGSSLNTARTFGPYLIDSLMGGPDL
                     WVYLPIYIIGPIAGAVIAAFFYDFITGESSAAA"
     gene            66556..66711
                     /locus_tag="PK679_02320"
     CDS             66556..66711
                     /locus_tag="PK679_02320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54824.1"
                     /translation="MCRKVMCPACREANARVAMMRAYVRPRGPDGKLRMVPVGWWCPS
                     CGGFRKE"
     gene            66779..67159
                     /locus_tag="PK679_02325"
     CDS             66779..67159
                     /locus_tag="PK679_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54825.1"
                     /translation="MGQWVKDTVGLGVFLWIIGYIASILLFFSPYAPLMGWIITPVFT
                     PVAIAITWWWFRKRKLPLSYYIRVGLAWTAIAIVFDYLFIVVLFHATYYGIDVLIYYS
                     LTFLIPVGVGLFLNHREGKKNVAG"
     gene            67504..68577
                     /locus_tag="PK679_02330"
     CDS             67504..68577
                     /locus_tag="PK679_02330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HPC54826.1"
                     /translation="MIDALIGSLLLGWETLAGYLQEHVVTCLVPAFFIAGAIATFIKK
                     EAILKYFSPDSPKSIAYGLASVSGTVLAVCSCTILPMFAGLFKRGSGIGPATTFLYAG
                     PAINILAIVYTAKVLGFDLGIARAVFAIVMSIIIGLIMATLFRSYDTETRERMKLAPS
                     VPAGEKPERPGWVVPLFFVLLVGILVTATAQVDWMIKFPLIYAMTLVIAYLLIYFFER
                     DEVTEWGYETWDLTKKIFPILLVGTFALGMLAFFLPPESFRPFFGNNSILSTLLAAIV
                     GTILYMPTLLEVPVIGTTFGYTSGVMAGGPALSLLLSGPSVSLPSLLVLSRIMGPKKT
                     VTYAVLVIIISAVAGYIYGLFLG"
     gene            68591..68851
                     /locus_tag="PK679_02335"
     CDS             68591..68851
                     /locus_tag="PK679_02335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54827.1"
                     /translation="MVEKEKPCCAAEALRRIRQVDVGGITVGLAMLDDIIDEVQELHL
                     PTRDAIINELIRRVKVYNYVPPSAEEKYREAIYREYEEKVKP"
     gene            68848..69087
                     /locus_tag="PK679_02340"
     CDS             68848..69087
                     /locus_tag="PK679_02340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HPC54828.1"
                     /translation="MKIEILGTGCMKCRRLTKNVEQAVAELGVSADIQKVEDITAIMD
                     RGVMLTPALIVDGELKVSGRVADVAEIKRILTGGA"
     gene            69089..69565
                     /locus_tag="PK679_02345"
     CDS             69089..69565
                     /locus_tag="PK679_02345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc-binding protein"
                     /protein_id="HPC54829.1"
                     /translation="MAEIPSCTCGQNEKKRIIFPCAGQANTGQITNLAAIQLTEEGYG
                     SIACASLLAIGSEGLVTSARNVDEVVVLDGCPMECARKIAEAQGVPISQHLVMTGLGI
                     TKGPSRSYTADDIEKVVSACWAGEGKGKGKGKDTRTGSKKGADPGTGCGCGCGGTC"
     gene            69784..70863
                     /gene="arsB"
                     /locus_tag="PK679_02350"
     CDS             69784..70863
                     /gene="arsB"
                     /locus_tag="PK679_02350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008490 - arsenite secondary active
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACR3 family arsenite efflux transporter"
                     /protein_id="HPC54830.1"
                     /translation="MTERRLSTFEKYLTVWVALCILAGIGLGAVAPGVAVALDSFSVY
                     QVSIPIAIALFFMMYPIMVKIDFAEVLKAARTPKPVALTLFINWAIKPFTMYLIATFF
                     LGYVFVSFIPGTDVLANGSTVELWRSYVSGCILLGIAPCTAMVLMWSYLARGNDGLTL
                     IMVAINSLTMLVLYAPLGGFLLGVNAMPIPWETILLSVAIYVGLPLLAGYYTRKWIIR
                     HKGMAWFETKFLHLLTPVSIVALLGTLVLLFTFKGNVIVENPFTILWIAIPLFIQTML
                     IFTIGYFALARWLKLPYRDAAPAAMIGASNHFEVAIATATILFGLASGAALATVVGVL
                     IEVPVMLMLVKICLRTQGLFKGEPV"
     gene            70860..71723
                     /locus_tag="PK679_02355"
     CDS             70860..71723
                     /locus_tag="PK679_02355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HPC54831.1"
                     /translation="MKMDSMLVPLEIHGAGAVMVPAVEEIARLGVKRVELLYVMNIRE
                     TAGDPGLYAHDRQVMNDWKNRIEACGVRDVKAEVVTGIPWIEILERSEALHPSLIVMG
                     SHGRSLIPRMFLGSQTENVLHHARVPLLVLRVSIMKEGDRDTCTLNTGIFRRVLYLTD
                     FSAEAERCIPFIEWMAGAKPDRLVIMHVQDTRRLWTASQDQISEFNQKDAKRLADLKA
                     RFENMAIPQVVTELVTGNAIDEILAVEETFHPTMIVMGAKGRTGTVSSLLGGVAEAIV
                     HRAKAHVLVVR"
     gene            71825..72349
                     /locus_tag="PK679_02360"
     CDS             71825..72349
                     /locus_tag="PK679_02360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54832.1"
                     /translation="MATIERWLGNPVTRFLLQWLSSDCSRCGNRLEVALFRFTHGGSA
                     PCISCRMASWLVGITLRRSGKAFGVREDLMKEGLLDPYLRRGLTTVIRSIARHGITRP
                     QRINAPFLVVWDVTHRCNLRCIHCYQDACQALPDELDTGEAKGVIDQLARAGVVAISH
                     SRAVNRSCAPISGS"
     gene            72325..72675
                     /locus_tag="PK679_02365"
     CDS             72325..72675
                     /locus_tag="PK679_02365"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC54833.1"
                     /translation="MRPDIRELIRYAKEKGFFVSLASNGTLIRDALAQDLASDGLDYI
                     EISLDGADAAHHDLFRGIPGAFDRTVTGIRACVSAGLDTGVATTVTRETVDHLPAIHQ
                     LAAILGASMPLDCS"
     gene            72754..73815
                     /locus_tag="PK679_02370"
     CDS             72754..73815
                     /locus_tag="PK679_02370"
                     /inference="COORDINATES: protein motif:HMM:NF013885.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54834.1"
                     /translation="MAGEDPGDVMRANGVLLRYAVFMREHFAIVIISTLLLAIAVGLV
                     SSAPGRFLQQYSVILIVIMIGAMGFSITYESLSASLKEWCARCLSLGLVLNFLFAPFL
                     CWLLALLLLQGYPDFAVGLVLIGAVPCAGMAMVWTGLLKGDLPLATVINAVTMVLAPF
                     LIPVIMLLFAGRFVVIDTAAMFVQVFLTVLLPLLIGISLREILEWRSCTLKGRGDAQR
                     PQAVREKELTVQHILPVMSAISATMAVLLMFMAINTSIPVIVKNLSAIIPLIASTILI
                     FPVLFIVAYFISERLFPHAQNIALTYSAGMKNLPIAIGIATVSFGGLAMLPVAVGFAF
                     QMLTAVGFYQVYRKLTSAA"
     gene            complement(73852..75030)
                     /locus_tag="PK679_02375"
     CDS             complement(73852..75030)
                     /locus_tag="PK679_02375"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54835.1"
                     /translation="MAVLVALILGMVSVPADAGWVTKTISDNSTNALGGKISGDFVLF
                     TGRVEGPDDSQNRIYLYRISTGEKKTVGLPSVNMTITGPEISGEYATWFETPQVDFGP
                     GTTGIAQNRVFLCSIRNGSAGIIDDTGNAWWPRIDRGKIIWQNDVSEGLDTRIVLYDI
                     DTGERKEVCTLPIVNPAAVLFNGDRIAYLGRNGLFLYSLTDNINTEVFRNNAGNVSNT
                     GVSDYAMKGDYLVYTTRRITFEGQDKGSFKELFLYVISTGKTERIDPVSGTLLGSSQP
                     PAGTERSPDISSPFTDGKRIGWVYTENSPRSSIVLCDPQTGAVEKISLDGIACDVSID
                     GDRIIWVESHFPSFHGDLVLAQEIPDSGEDMRAAAPGFSSCIGILALMGALMLLCRKK
                     "
     gene            75273..76706
                     /locus_tag="PK679_02380"
     CDS             75273..76706
                     /locus_tag="PK679_02380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HPC54836.1"
                     /translation="MWQLVGKPPLRRHTGQGENRADRQAVLLIAILTSFLTPFMISSV
                     NIAIPAIGSEFGADAVLLGWIPTSYILASAIFLIPVGRLADIHGMRRVFFPGIVIFTV
                     ATVFCAFSVSTPMLIGLRVIQGIGNAMVFSTAVAALTAVYPPGKRGMVLGLSVAASYI
                     GLSLGPVLGGVLTLNLGWRSIFLAAVPLAVIIIMLLVRNGHEWTGTCQEKFDLAGSVL
                     YGFMLLCLMYGLSLLPGTEGWALVLFSMPLFAALIFWELRTDSPVIEIDIFLKNRVFS
                     FSSIATMINYCATFAISFLLALYLQFNRGFDPQTAGFILAAQPVVQAIFSPAAGRLSD
                     RVEPGVIASAGMGATAVGLAMLAFLTEETPLFFLVAALIILGLGFALFSSPNTNAIMS
                     SVGREFLGVASATVATARQVGMMLSLGITMVIFSLIIGRVQITPDVHTPLLASIRIAF
                     TLFAILCTVGIYFSLSRGKVRENALVT"
     gene            complement(76917..78326)
                     /locus_tag="PK679_02385"
     CDS             complement(76917..78326)
                     /locus_tag="PK679_02385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HPC54837.1"
                     /translation="MTDTSDKSGVTPDRAFDEQLTKGVSILRGDPEVAVRKLAGPMIV
                     AMLLIAIYNLADAIWVSGISSDALAGVGFVTPLFMILMALSNGLGAGATSVVARCIGA
                     RDKEGADTAASHAILTAFIVSAFLMIVFVLFLRPIVVLLGAGPVTDIAVEYGQIVFLG
                     TVFFLVVQMAYAVLRAEGDTKRTMYAMAVSSVLNIILDPILIYGAGLGVAGAAIATVI
                     SIASVLVVLAYWFLVKKDTFVNLKIRGFPPDMRIVRSILGVGIPASLEYLLLSVMSLS
                     INLILVTIAGTDAVAVYTSGWRIVMFAIVPLIGIATSVIAVSGAAYGAREYEKIRIVH
                     RYSIRIGVVIGLVTGILTYLLSPQITALFTYSPGSAHLSPAFILFFQTMCFFYPFIPL
                     GMFSSSVFQGTGHGFTSLVISLLRALAFDIVFAFILGMVLGLGEFGVYSGIVVGNIIG
                     GFIGYLWAGVFLDRLVRIG"
     gene            complement(78319..78768)
                     /locus_tag="PK679_02390"
     CDS             complement(78319..78768)
                     /locus_tag="PK679_02390"
                     /inference="COORDINATES: protein motif:HMM:NF024212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HPC54838.1"
                     /translation="MHPDLPLGAFFSLIHRNHSIALNRHLVPRGLAAGQFPILMYLSR
                     KEGVMQETLARFFYLDKATVARAVRRLERSGFISRKKIPGKRRAWGLFLTEKGRETIA
                     EILGIEAEWEGELLSVLAGEERDMVRDLLGVLARQSMHLIGESCGDD"
     gene            complement(78921..79523)
                     /locus_tag="PK679_02395"
     CDS             complement(78921..79523)
                     /locus_tag="PK679_02395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54839.1"
                     /translation="MKKTHVILAVILAIAICILLGMCLLFCDQIQEGERVTPDPGATR
                     DITGNGTPAATPAGDRLAEMTLVQTRETIPVTVTPTPGPRPVAFTLDSGAPSVCGLTC
                     RETTATIANTGDETAHSVCVVLEVFNDAGERIFINGAPSIERCIGDLPGGSLRMETIQ
                     INADCGFLATRCIGHTLILKTRVRSLEKSEEFPDIFMQVS"
     gene            79676..80401
                     /locus_tag="PK679_02400"
     CDS             79676..80401
                     /locus_tag="PK679_02400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC54840.1"
                     /translation="MAAVIETKGLSKVYGDVTALDSVSLSVEKGTLFGLLGPNGSGKT
                     TMIKVLTGQIRPTGGFATVLGLDAEKEGIRVREKVGIIPEQESPPSFLTAMEYLEFVG
                     AVRKIPDIGERAEKWFELLEFGDKKDVLCKDLSRGTRQKLMFAQAFIHEPVLALIDEP
                     LINLDPVMQDVVKEFLSDYVRKGNTIFVSTHILEVAEEICSRFAILHKGKLLHAGSVA
                     DVTADGGHLPGFFLSLVRKGGHA"
     gene            80394..81800
                     /locus_tag="PK679_02405"
     CDS             80394..81800
                     /locus_tag="PK679_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54841.1"
                     /translation="MPDLFSCLMKEEWRMHSTMFGSISFALFPVMIFGIVFMGSFLLP
                     LLSVAFPAGDLAFLAHASFLLLGFMVGGFGLLGNEMMNRRFGQASLLVYSSRSLPLSE
                     RFIFTNFVVKDIVYYFFLWVLPFGGGYIAASPFLGVPLSRALLLLLTLSLSFLLGLCV
                     VFLLSSLYVRSKAACLLIVIFLGIAGGVYTIWSGTNPTLLFPPYLLYSAFSWMTFLGT
                     SIAVVTMFLASVVLFSPEGTGLSRTYRRRLGRLARVLSFLPESPIVAKDFLDLSRSGI
                     GIGQALFSFVLPLVVIWFFLSLLRSSFPPNGLVVIFSLTAGIIASTIYTWVTEFDSFG
                     PYSCLPVAVSTLIAGKMTTFLFLQVLPAVFIGTVAGISAGPEMIAPAIVLCLSISIYA
                     AAVMAFLCGLSPSVLVYDVRVLLTYLVLDGVALVLFAAVSFASSLYAFLSVFLLFPAY
                     LLFRAAGARWDARDPAGI"
     gene            81960..>83683
                     /locus_tag="PK679_02410"
     CDS             81960..>83683
                     /locus_tag="PK679_02410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase family
                     protein"
                     /protein_id="HPC54842.1"
                     /translation="MDAYAGKIADIDLTRKKVTITATPSDWKKRYLGGRGFGARVVTD
                     RVNPRDDPLGEKNVFVLASGPTTGTGIPLGSRYEISAKSPLNGTLMSSNSGGVFGWKL
                     KRAGFDAVILNGKAEKPSYIYLNEGKAEIRDASPYWGKTTHEATEMILSDLGDTKAKV
                     ACIGPAGERKSLLACVINDMDRAAGRSGGGAVMGSKNVKAIVAAGDLSIGIADEERLN
                     TVKERVREKLEKNGICQALTKYGTAVLVNIINEAGILPTRNFQSAHFADAEKVSGEAL
                     AEKYLKKNKGCYACIVRCSRVTEVDGEIHEGPEYEPLWAFTADLGINDLAFATKATWL
                     CNKLGLDAIGTPTAIACAMEMKEKGYIRDGPQFGSAEGILDLIRQMAYREGFGAELSD
                     GSYRFAEKHGHPELSMSVKKQDIPAYDPRGLQGHGLEYATSVRGADHVYGYMVSPEVL
                     GAPVKLDPYTSEGKAQWTKTFQDLTAAIDASGMCLFSSFALDADDYADLISAATGMSL
                     TGKGLLHIGERIWNLQRLYNLKAGYTKDDDTLPPRLLNEPLREGAPKGRVWQRQPLLD
                     EYYELRGW"
BASE COUNT        17640 a        23748 c        24260 g        18035 t
ORIGIN      
        1 gaagtgttct gccatgttaa gggaaaaagc cctggaggag tggatcgcga accgttctgc
       61 agggctgact tctgtcaggc ccgccgtgga agagatcatc gcacgggtca gggacggggg
      121 tgatgcagca ctgcgtgaac tcacgcagaa gtatgatggt gtttttcggg agagcatcag
      181 gattacccct gaagagatcg aaaatgccta ttcccgcgtt gacgaaggct tcatcaggag
      241 cctcgaggat gcccgatcga ggataacgaa gttccacgag atacaaaagc cgaggaatct
      301 ctggctcgag gagatcgaac cgggcatcgt cctcgggatg aggatggtcc cgctcgaccg
      361 ggtcggtgca tacgtgcccg ggggacgggc tgcatatgcg tcgacggccc tcatgacagt
      421 catcccggca cgcgttgccg gtgtcaggtc ggtctgctgt tgcagccccc ctcctattgc
      481 tccccaaagc ctcgttgcaa tggatattgc aggagcggac gaggtgtttg cagtcggcgg
      541 ggcacaggcg gttgctgcaa tggcacttgg gacggaatcc atacgacccg tccgaaagat
      601 agtcggtccg ggaaacgtct atgtcacgac ggccaagatg ctgctgcgtg ataccgtgga
      661 gattgacttt cccgcaggtc catcggaaat cgttatcctt gccgacggat ccgcaaggcc
      721 ggatttcatt gcagcagaca tcgtcgccca ggccgagcac gacccgaatg ccgcgtgcta
      781 cctcgttgca ctggatccgt cgctacccgg aaaggtcctg cgcgaactca tcttgcaggt
      841 cagggaatcc ccaagaaaag agatattgga aaaagcactt gaaaataccg ggtatacact
      901 agcagcctcg attggcgagg cattaaccat catcaaccgg gcagcgccgg agcacctgtc
      961 cctccagatc aatgacccca tgcaggttct catgcatgca gggtatgctg ggtcggtctt
     1021 cgtgggttct tactcggctg tcgcctgcgg ggactatgca tccgggacaa accacgtcct
     1081 cccgacggca ggctatgcca gcacgtattc cggtctcgac gtcctgcatt tctgcacgcg
     1141 gtccacgatc cagatgataa atcaggaggg gctttcgagg attgccgata cggtggagac
     1201 gcttgcacgt gccgagggac tggaggggca tgcccgatcg gtccgtatca ggagaccggg
     1261 agaaaggaaa aatgcctgaa ttaatgtcct gaatgccttc attatggatt cattctcatt
     1321 ttttggaaag taatttcacg ggccgccttc ttttctccgg tacaaaccga gggttgcggt
     1381 gaccaggaag aagagaaaga agacgcaggg actaaacccg gggagtgaac ggggaggagg
     1441 tctcctgaat gtaacctcgg ttgaagagac cgagatgctg tctgtatcag tcaggcgggc
     1501 aaggttcagg ggtacattca cggcataaat cctgtatttc ccgggaacga ggtttccgac
     1561 gatgaacgag gtgtcccagt cgtaggcaaa cgatccatcc gggttgacaa aagccgacgt
     1621 gaagtagcct gaacctgccc tgaggtggat gttttcaagc gtgactcccg ctccgtcgag
     1681 tcccggccct gtgacgaaga gaaagatggc tatcaggttc tttccatcga tcgtcccgtt
     1741 gatatggatc cggtccccga tatacgcatc gtggggcgtg gcatcgatcg agatggcgcc
     1801 ggttgccgct cctgtcacca cgagaaaaaa tacgaggagg gaaagaactg tccgaagccc
     1861 cataggtccc ggatagtatt ggtcaggaat ctccattagt attctggtgg gggcagatgg
     1921 aaggtcgatg gtcagaactc gaccaccatg acggcctcct cctcgtcttt taattctccc
     1981 ttgagatgtt ccgcgtcgaa atggtactgt tcccaggggt cgtagtcatc gtagagctcg
     2041 cacttgtcga ggacatcgat gaattccttg aggaagatcc tcgggataac atcaaccctg
     2101 cccccgaatt ttttcgttac ccgggatatc atggcccgga taaaccggtg cgagaccctg
     2161 cttcggtcca cgtccgagta ggcctcgcgg tatatctcga tcactttcag ggcgacctgt
     2221 tcgagttttc tggcatcgaa cctcgcgaga gcaatctgcg gctggcgagg gtttttgaac
     2281 ccttcttcag gctgcacgac gctgatccgg tcatagagcg ggggaagggt ccgaatcccc
     2341 cggggaccat cgaagaacgc aggtgtcccg gtgaaaagga agtaggaatg cgagagatcc
     2401 cccctgtcca gggattcgac gatcatctgg agggtatggt agcttttctc ccgctggttt
     2461 cgcggaagtg actgggttgt ctcgacctcg tcaacggcaa cagcaagacc cctgtacccc
     2521 gcgctcacga tgatccggac aagcccgcgg aggaatatga aggccgatgc ctcgtcgatg
     2581 tcaccgcgta tccctgcctt ctgcttgaag tcccgaccga cgttggactc ggcacatatc
     2641 cacccgatgg cagactgggc cgtctggaaa tcaccctcgt tgcttgaccg gtaataggtc
     2701 ctgagtgcgg ctgcaaggga gctgttcagt tccgatattc ccgcaagagc actctctatc
     2761 tcggcgagtg tggccttttc gagaacgtcc tcgggaagag tctggtcgct cactttgagg
     2821 atgcgttcct cgattccaaa gagccatgta tcgatgattg atttcggggc atgctcttcc
     2881 tcccgggtcc gcagtgtcgc acagatctgg cggtacagtt ccttgagctt gtgcagaggt
     2941 gcagacggcg aaataacaac gtgggcggtg acgaaacctt tttccctcgc gatctcgagg
     3001 gcacgtgcca cgaggaacgt cttcccgctg ccatagtcgc cgcggatgaa cttgatatcc
     3061 cctcctccct gcgagacgta gtccagctgt gccctgatga caccctcttc catgtcgagt
     3121 ccgacagcta tccgctcgag accgctcccc ggaacagtcc ccctccgcag cgcattgatg
     3181 atgttctggc tttccagttt ccgcggtccc cggatatcag gtgttcctgt aggcatagat
     3241 ttctccatcc tttcccactc ccttcttttc tatcagcacc aggcctttac ttgacgcttt
     3301 ctgcatgatg cggttgatta tccctgccac ccgccgcgaa ccaagcaggg tccggagctc
     3361 catctcggtt gcctggtgac gggtccttaa gaattcaagg atttttctct cgttctcgtc
     3421 caggtccagt tcgaggagcg atgtatcatg tggttccggc aagcccgtct cccccctctc
     3481 cgggtgtaaa agaacgggaa tttccgaaag ggaccgtttc ttgcactcct cgaggagagc
     3541 gaggaaatcc ccgggtctga tactctctgc atcctgggga atgacgtcca gtcctgcaag
     3601 gcatgaccgc ttgcatgaca tgcagtcccc tttttcgagg gagacggatc cccacaggag
     3661 gtatatcgtt gcaaggattt ccatgcccct ggacgggagg atctcggtga cctcttcgag
     3721 ccttgccttc agcctctcga gcagcctggg catccggaaa agagcatcct tgtcctgcag
     3781 aaagacctct gcgacacgga gcaggtcccg gactttccgg gctgtcccca ccacgtagat
     3841 catgaccttc tcacactccc ggttatcccc gttccggtaa cagaaccagg cgtacagggg
     3901 acctccccgg atcgaatcac tccggtatgc ccggtaatac caggaacgtg cttccccccg
     3961 gtctccggcc tcctcgtaga agcgggcaac ggtaagaagg gaaaacgggt ccgtccgggc
     4021 agaaagcgat gcaaggagaa gggattctgc ctcccggaag gggtagtggg tctgtagaaa
     4081 agtcctgaaa ctggaaagga tatcctggat gaacgccggg tcggccatgg aatcaagttc
     4141 gcggtcaagg agatcgcgat aatgccggac cgcctcctcc tttctctgca gcagggccaa
     4201 aagctcgcat tccaggagaa ggtatttccc ttctgtcctc tccccgagga ggaggggacc
     4261 gagtccggcg agtgcctgcc cgaagtttcc ctcttctttt tggaagagga cgaagtcata
     4321 ccgtatctcc cgatctcccg ttatctccac gagacggggg tactcttccc tggccctctg
     4381 ccggtcggtt acggagagtg cttccaggta cctgcgggcg aattgcggat cttttgtttt
     4441 ttcgaataat tgcagggcgg attctgcaac ctggctgaac ctgccgcagg caaaaagaat
     4501 cgcaaggtat tcttcgtctg cagccagtcg tccgcccggg acattctccc ataccccgag
     4561 tgcctccgac gggcggccgg acatgaggag tgcccgggca aggagccggg catcgtctgc
     4621 ccggcgggaa tgcgaataga ggcgggaaaa cacaggaacc gcctttttgg ggtctcctga
     4681 tttcaggaca aatgatgcaa aactccgcaa tgcttcgagg tttccggggt cgagcgcaac
     4741 agcccgtgca tactcggcga gtgcaccgtc gtcacccttc atttccagga tccggcccag
     4801 gtaactgtgc acatgcgaag tcccggggag ggaatgggaa aggtcccgga agaaagcctc
     4861 ggcctcctcg agcctcccca tgtgaaaaag gttcgcagcg cacagaacgg agatcgaagg
     4921 gtcatctgca acctgcctga gatccctgca cagggcatac gaccgttcgt attcaccctt
     4981 ttcaaaaagg gtgaaagcat cccttttttg gtcttcagga gaagataagg acagggtata
     5041 tcacgctccc aatctgaggc ggaccaggtt cgcaagcatc ctgaacccat ccgttcccct
     5101 gacgttggaa ctgctcgtat cgcgccacgc tatgggatgt tccctgatgc agaaccccct
     5161 ccttttcagg cgccagagga gttccacatc aaattcgaag cctgatgaga ccatttccct
     5221 gataactgcg tcaattgctg attttttaaa tacttttgca ccgcactggg tatccctgaa
     5281 gggcagacca aaaaggagcc tcacaataca attgaagatg cggctctcga tcctgcggga
     5341 aagcccctga ggcttttcga ggacggctcc ctgcacccag cgcgatccta tcacgccgtc
     5401 tgcgtcgtcg atgagggaga aaaggtcccg catctgggaa aaggacgttg aagcgtcagc
     5461 gtccatgtaa cccacgaggg gtgctgaagc tatcgccatc ccctccctga tggcacctcc
     5521 ctttcccatg cgttcgggac ggtgcaggca ccggatggtc atttccggat gtgcccctgc
     5581 aaactcgagg acaagtcgtg gtgtttcatc gtttccttca cacacgaaga tgaattcacc
     5641 ctctgccccc gctatctgcg aaagaaggag gggaatcctg tcagcctcgt tgtaggccgg
     5701 aatgaccagc gtaaacgcgg gtgatggagg gtgcgttggc tttccgctca aggccggtat
     5761 ctccgtatcc ccggtatctt tccccgtgtt atgagcccgt cagggtgtcc gccgttgttc
     5821 atgcatgccc gttaatgtgt tctttcaagc ccgagcccgg cctgtatcgt tctgcaattg
     5881 caactgcgtg ttgccggaga cgattgtgat cctcgataca cgtccggggt ggcggggatt
     5941 tgcgcagtat cgaggaggtg ttttccgtta tctggatgag ctctgttgca atcacggcct
     6001 gcagccagat caggtctgca agcatctcct tctcttccct atccatgcag gagaggttgg
     6061 tgccggaact gaataattat ggcgggagtc cgtgcacggg atcaccaagt atcttgggca
     6121 ggaggtgcag ataatctgga gcatgagcta ccttgaaaag gtgagaaggg aagggaggga
     6181 tgcaaacccg ttcttcgttc tcatgggtat agacgtgcaa gaagccggaa cgggaagggc
     6241 cgtgctccgc atgccggtcc ggcctgacat gatgaacggt gagggctggc tccagggcgg
     6301 catttattgc gcgcttgcgg atgaagcaat ggtccttgca gtataccctc tgctctctcc
     6361 cggcgatacg attgccacca tcacagagac gacaacgttc cttggtggca cacgggaggg
     6421 ggtcctcttt ggtctgggca gggtggtcag gaaaggcagc agggtcattt ttgccgaggg
     6481 ggaggtcagg agtgagagcc cggaaggtcc cgtcctctcg cgcagcatcg ccacattcat
     6541 cgtgaaccgg acacgcgtgc aatgaacagg tgagaaacca aaaaggggaa atgaaaagat
     6601 gccgggaagg aaacgcgggc tggtgccttg gcaccgtcag ggcacgctcc agacgctgaa
     6661 ccctgttccc gtgataattc ctccccttgt ggcttttgca gagggcttct tctctccgtt
     6721 gggattggag agcgcatact actttttctt cccgtgaagt gatactatac tgacaggcgg
     6781 gggactccct gaaggaaggg ggttcaaacc ggaccagcga aatgcagagc ggcgggaacg
     6841 aaggaaaccg gcatgattct tcgtccctcg agggagaacc cgcaggaaca ggccgggaga
     6901 cgggaccgat gaaatttata gttatcacgg ggggggtcat gagtggtctt ggaaagggga
     6961 tcactgccgc atctgtcgga cggattctta agaacagggg gtatgcggtc acagcggtca
     7021 agatcgatcc gtacctgaac attgacgcag ggacgatgaa tcccggccag cacggggagg
     7081 tattcgtcct ttcggacggg agcgaagtcg atcttgacct gggtaactac gagcgctttc
     7141 tcgacatcga tcttaccgct gcccacaaca tcaccacggg gaaggtgtac cggagtgtca
     7201 tcgaaaagga gcggcgtggc gacttcctgg gagagactgt ccagatcatc ccccatatca
     7261 cggacgagat aaagtcctgc atcaggacag ccgcgacgag gcagatcccc ggggagcctc
     7321 cggcagagat atgcctcgtg gaaatcgggg gaacggttgg cgatatcgag agcatgccgt
     7381 tcctcgaggc ggtcaggcag atgaggggcg agctgccacc ccgggacaca gtcatcattc
     7441 acgtgactct catcccggag gacacgatgg gtgatctgaa gaccaaaccg acgcagcatt
     7501 cggtcaaggc cctgcgcgag ctcgggctcc atgctgacat catcgtgggc aggagcgagc
     7561 gccccatcgg cacccacacg aagaggaaga tttcggcatt ctgtgacctc cccatcaggt
     7621 gcgtgataag cgcggcgacc gtcccggaca tctaccaggt cccgatggag ctcgagaagg
     7681 agggacttgc cgatgccctc acagaccacc tcggcctcga aaagagaact gcggacacgg
     7741 aatggtaccg catcgtgagc agggaatata cccgcagggt gagcgttgcg atagtgagca
     7801 agtatggcat cgaggatgtc tacctgagca tcaaggaggc attgaaacac gcgggacgat
     7861 ccctttcgac cgaggtcgtc atcacgtggc ttgacgcgga gaggtacgag ccgaggcagc
     7921 tctctgactt cgatgggatt ctcgtgcccg gtgggtttgg aaaacgggga atcgaaggga
     7981 agataggagc aatatcgtgg gcaaggatga acaggactcc gttcctgggc ctgtgcctcg
     8041 gtttccagat ggcggttgtt gaatatgccc gcaacgtggt cgggtgggaa gatgcgacga
     8101 gcgcagagat cggcgagggc aggcacgtga tagcgatact gcccgagcag caggaggtga
     8161 cggggcttgg agggacgatg cgcctgggtg atgcacccgt aacgctgaaa agcggcactc
     8221 tcgcagaaaa aatctatggg aaacgggaga taacggagag acaccggcac cggtacgagg
     8281 tcaacccccg gtacattccg gatctcgaaa agtcaggtct cgtcttttcc gggtatagcg
     8341 ggaatcgcat ggaggttctg gagttacctg accacccctt cttccttgcg acccagttcc
     8401 atcccgagtt caggtcaaga ccaacccggc catcgccccc cttcctgggc tttgttcgtg
     8461 catgttcagc gaaaaacgga aaaccggcag ttggtgaggt gaaaaagtga tcgatcccct
     8521 gaagttcata gaccaggcag tggaggagat cagaaaagag gcagaagacc gcagggtggt
     8581 catggccctt tcaggcgggg ttgacagctc cgtctgtgcc gcccttgcag cccgtgcaat
     8641 cggggatcgc ctcgaaccga tatacgtcga cacggggctg atgaggaagg gagagacaga
     8701 acgcatagcg caggtattcg ggaacctgcg gctccatatc gtccctgcgg ccgacgagtt
     8761 ctttgcagcc ctcaaaggag tggtggaccc cgaggagaaa cgcaaggtaa tcggcgaacg
     8821 gttcattcgc atcttcgagc gggaagcgcg gagaaccggt gcccgtgcgc tcctccaggg
     8881 gactatctac cccgacagga ttgagagcga gggtgggata aagagccatc acaacgtcgg
     8941 gggcatgccc ctcgagatcg cgtttgaaaa ggttatcgaa cccctccggg acctgtacaa
     9001 ggacgaggtc agggagattg cccgcgccct tggtctcccg ccggagatcc agcaccgcat
     9061 gcctttcccg ggtcccggtc ttgcagtcag ggtcatcggc gaggtaacga gggagaggat
     9121 agaggtggtc cgggaggcaa actggatcgt cgagagcgaa atcgttgacc agttcaagcc
     9181 ctggcagtgc tttgccgctc tccttggtct cggaacgggt gtaaagggcg ataacagggt
     9241 tcatgggtgg atcgttgccg taagagcggt caactcgcgg gacggtatga ccgccgaccc
     9301 tctcaggctc ccatgggagg tgctcgagcg ggtggcactg cgcatcacct ctgagattcc
     9361 cgatgtcgca agggtcgtgt acgatatcac tcccaagccc ccggccacca tcgagtacga
     9421 gtagaaaaag aatttaatcc ggtatcgaga acaagtgaag gaaaaagacc ctgataaaat
     9481 ggagaatcaa ggaaactttc gggaactcga cgcccggtat tacatgccgg cgtttggcag
     9541 ggagatcatg atcgtcaggg gacagggttc ccgggtctgg gactcctcgg gcagagaata
     9601 catcgattgc gtggcaggaa tagcagtttg cagtacaggt cactgtcacc ccggggtgac
     9661 aggagcgatc tgtgaacagg caaaaaagct cattcactgc tcgaacctgt actatgtacc
     9721 cgggcaggcg gaactggccg agaagctcgt cctcctgacg ggaatggcaa aggccttttt
     9781 ctcaaactcg ggagcagaag caaacgaagg tgcgataaaa ctggcccggc tcgcgacagg
     9841 gagaaagaag ttcattgcct tcacacatgg ttttcatggc aggacgatgg ggtctcttgc
     9901 tgtaacacac aagcctccca tccgcgagcc ttttctcccc ctcgaacccc ggtgcacctt
     9961 cgtcgagtat ggtgacctcg atgcactccg ctcggcaatg ggcaacgata tcgccggcgt
    10021 gttcgtggag cccatccagg gggaggcagg tgttatcacg ccgccggatg gcttcctcga
    10081 agggatccgt gacctctgcg acaggcatgg tgccctgatg atcgtggacg aagtccagac
    10141 cgggatggga cgaacgggga aatggcttgc aatccagcat acggatgtcc gtcctgacat
    10201 tgtgacactc gccaagggga tagcgagcgg ttttcccatg ggcgcgctgc tcgcccgtga
    10261 ggggctcgag ttccaccggg gagagcacgg gagcacattt gcaggcggtc ctctggcctg
    10321 cgccgcggcg ctggcaacga tcagggtcat cgaggaggtc atgccctcaa tcccggcaaa
    10381 ggcagagctc ttcaggacca gtctatcccg cttcaacccg cgggtgaggg gactgatgat
    10441 cggcatttca gtcggtgaca aatgcgggga tgtccagaaa gcctgtgcgg agaggggctt
    10501 actcgtgaac tgtgcagccg atggaaatct ccgtctcgtc ccgcccctcg tcatcacacc
    10561 ggaggagata cagacggcct gcaggatcct caccgaggta ctcaccgcga agaataagct
    10621 ccctgcaacc ctgtgatgaa ccccaccaaa agtcccctgc cgggatggtg aaaagcggct
    10681 ggggaaatgg gaagggggag gattgaaatg tatccccctt ttttcaggct tttttggcgc
    10741 tttcgaaccg ggaaccgact gtcttccagt ttatgatatt ccagatgttt tccaggtatt
    10801 ttgcccggtc attcttgtaa tcaatgtaat atgcgtgttc ccatgcatcc accaccagca
    10861 ggagggggaa cccgggaaaa acgttcacgt tgtgtttttc gatctgcatg acaaggagcc
    10921 tccccgtctt tttacagtaa gagagcgctc cccatcccga accttccacg ctgtttgtgg
    10981 ctgctatgaa ctcttttttg aacctttcga aggatccgaa gtccttatct atctgttttg
    11041 caaggtcgcc gccgggactg cctcccccgc cctttcctgc cggtgcaagg ttctcccagt
    11101 agaggacatg gaggaggaaa cccccgatat ggaacgagag ttcctttgcc actgccttct
    11161 ggtcaggatc actgccttct ttccgtgcct tctccagttt ctcgaacaca gcatttgcac
    11221 cgttgacgta accctggtgg tgcttcgtgt ggtggatacg caactgctct tccgagatac
    11281 tcggtgcaag atcgcggtaa tcgtagggca gtgcaggaag tgtgtagaga cggttctggt
    11341 ccattttttt caactcctga caagggatag ttcttctgaa tggtaatata aagtcgttcc
    11401 cgtcatggca cactattaat cagtttcggg gtatcgggat acaggctacg acagatatac
    11461 agggtagtca aggggacggg aaagagggga aaaccggaaa gacctgcata tcctgcactg
    11521 cgcttttaag ctggaagagc ttatactgga aggacagagg tgaagggcca aaatgacagg
    11581 aaagcagggt ttttgctacg attcactggt ccgggactgc taccgcagcg gcgggtacgt
    11641 gtatgctgcc cgtcccgggg atgtcacggg aaaaactggt gtcacccggg ttgcccggct
    11701 cgcgagtaac gaaaaccccg atcccccttc accgcgtgcc atcgagatgg gaaaggctgc
    11761 tctctgcgat gcaaaccgct atcccggtga ccaggtgacg gggctcgtca gcgcgttgca
    11821 gaagtaccac ggcccttacc atttcgtcac aggcgtggga atggatggtg tcatcgagac
    11881 cgtccttcgg acattcgtgt gtgcaggaga cagggtcgcg atatccacgc cgacattttc
    11941 attctatggc cttgcggcaa tgggccaggg agcagatgtc atcagtgtac ccagggagaa
    12001 tgatttttca gtcgatcccg tgcgttttgt ccgggaggca gtcgatgcaa aagtctcgtt
    12061 cctctgttct ccgaataacc ccaccgggac cgtgacccct gcgtccgacg tcgccgagat
    12121 actggaaggg ctgtccggga tcctcttcct cgataacgcc tacgtggagt tctgcaacga
    12181 ggagtaccgt cccctcatga aaaaatacgg caacctcgtc atcgggcgga cgatgtcaaa
    12241 ggctttctcc cttgcaggtc tcagggtggg gtatgcattt gttccggaat ggatggttcc
    12301 ctgctacacg cgggcaatga cgcctttctc cctcaactcg gtctctgctt ctgctgcaat
    12361 cggtgcactg gaagatgctg accatgtgac gagggcaagg gaacgggtga cgcggcttcg
    12421 tgacttcgtg tgccgggagt gcaggttccc tgtgcacccg tccggtgcaa acttcgttct
    12481 tgtcgatgtt gcgccccata agggctgcga tgttgctgcc cggcttgccg gacggggtgt
    12541 catcgtgcga tcctgcgaga gttttcccgg gcttggtgac cactacatcc gggtaagcat
    12601 tggggaggaa tgggagatga aacgcttcct cgaagagatc aactgcctat gatgacggga
    12661 ataacaggga caccggggac agggaagtct tcagtgggaa aggttctctc tgcccgtggt
    12721 cacagggtca cggagatagc agataccgtc acaggatatg tcattgaacg tgacgaggcc
    12781 cgcgatacac tcgtcatcga cgaggagcgg tgggccgcgg agttcccgca tgtcgacggg
    12841 ttcgtagtgg gtcacctttc ccatctcctc ccgtgtgatc tcgtcgtcgt cctgcggtgc
    12901 gaaccgccgg tcctgaagga acgtctgcgc aggaggggct acaaagatgc caagattcgc
    12961 gagaactgcg aggcagaggc cctcgatgtc atcctcgtcg agacactcgg cagtcatcct
    13021 gccgaaaaag tcctcgagat cgatacaact cacatggacc ccgtaacctg tgcagatagg
    13081 atcgaagggt tcgtgagggg ggagatcccg ccatgctcgg gaaacattga ctggtcagaa
    13141 tacctgggag aagaggtatg acactcgagt ttctccgtcc ccacatgtcc cgtatcatgg
    13201 gcccgtttat caccgtctcg aggaaggcag gggtctcgcc caatacactt accgtccttg
    13261 cccttttcac ttcagcgtgt gccggaacct tctactggtt tggtcatgtc ctcttcggga
    13321 cactttttgt ggccctcaat gccctcttcg atggtctcga cggagcactt gcacgggcag
    13381 agaagaagga gagcatccgc ggggattttc tcgaccatgt caccgacagg tatgccgata
    13441 tcctcatcat caccggtatc tttgccgggg gtgcagcagg gtgggaagtg ggagtcctcg
    13501 cgctcacggg ggttctcatg tcctcttacc tggggacaca gtcgcaggct gtcggaatgg
    13561 ggaggttcta cggtggggtg ctgggcaggg cagaccgcct ggtgctgatc atctgtgccg
    13621 gacttctcac gctcgttttc cccggaaagg tattctcact ctccatcctt gggtggctcc
    13681 tgctcgggtt cggcgtgatg gggcatgtca ctgcactgca acggttcctc tacgtctggc
    13741 gcaagatgcc ctgaagagct gtgccggaag tcaccacagc gggaccgtac cggatcagaa
    13801 ccatgaatcg agtgttttct gcccggaggc ggttttcacc ccgcccagag cattttcaac
    13861 acgttccggc gagaagtcga agccgtcgca gagcatcctg agtattccct ccctgtcggg
    13921 aggtctccaa tggagggagt attcttccgt cacgggcggc ttcgcgaaga aatggaagat
    13981 ctcttcccaa tcgacacctg gttgcctctc cctcatgacc tgctcgaact cgccgttcct
    14041 gaccatccgg agggctgtct ttgcgccaac cccccggatc cccgggttga aatctgtccc
    14101 cacgaggagc ccgacccgga tcaggtcttc ccgggagatc tcaaggccgg taaggacact
    14161 ggaaaggact attctctccg gcattatcgc aagggtccgt ccgcggacct tcctctttcc
    14221 gctcaccgtg aggttccgca cgaggacggg tgccccgaag aggagcgtgt cgtagtcctg
    14281 ggagacgaca taacgggcgt caccccgcat gaccatgtat gccgcctggg cctccccttc
    14341 gctcggggcc tggatccacg ggagcccgag cagggtgatg agctggcgcg atgtcgcgat
    14401 gatctcctcg tcgatcctcg atgaggaacg tgcctgcctg taggcctcct ctgtatcacc
    14461 ccgcaggagt gcctccttcc acttttcccc ggctttctcc cggacagccc ttctctctgc
    14521 aaccgtgtcc tgcttgaatg acgggggggt tccgtcgtag atccagacgg tccgtatgcc
    14581 cttttcgagc atgtttgccg tccggaataa tattcccgag aggtgcgacg tcacccggcc
    14641 ccgctgatcc atgaggggcg tcccgtcagg ctgtctgatg atgcttaaaa actggtaaag
    14701 tgcgttgtgg gcatcaacag ccgctattcc gggaagatcc tgccacgtaa cagggtcctt
    14761 gtaatcagcc aggatgtccc gcagtgcaac gcccatgtat ctctcccgaa tcgaacccga
    14821 tcagaaccta tctgtatact ctcttcgtga tttcttcgat aattgcatcg atgtgcgaga
    14881 cgtggttctc gtatttctgt gacatcatgg tggcaatctc ttccatgttc atccggatca
    14941 ttctctccct ctgggtgagg gctttctcga tccgcctgac cttccagtgc acgaggaaga
    15001 tcaggccacc cagcgatatc atcatcaggg ctgcagcaag cgatttgata aggtcaaagt
    15061 tcagactgaa tacaaggatc agggtggaga tcacgaggac gacaaggagg agagcatcga
    15121 cgacgtattc ctgcgtgtcc atagtgttag atggaaaacg accatgctta aaactaaccc
    15181 ggatttccgg agaccggcaa tgaccatgaa agatgttctc cccctcgccg tgatgcccgt
    15241 gatgctggtc atcattgaaa caggtgcact cctcctctcg cttcccctcc aggaggcagg
    15301 actcgcggca ttcgaagatc cgtcctcggt tgcaaaccca ttcatcttca tcttcatact
    15361 ccttgtcttc acgggatttc tcctgttcct catcaggttc gggttccgga ggataatcgg
    15421 cggaataatc ggaatttcca tattcttcac ctttgtctac attttcgggg cagtcctcgc
    15481 actcctgtcc cgcgatgccc tcttcgttct cggggggagt ctccttatat cagggattgc
    15541 aacaggagtt ctctacctgt atcccgagtg gtatgtcatc gattgtttcg gtatcctgat
    15601 agcttcgggt gcagcatcca tattcgggat atctctcgag atcatcccgg ttgccatcct
    15661 cctcgtcatc ctcgcggtat acgatgccgt ctcggtttac aagacgaagc acatgatctc
    15721 ccttgccgaa ggagtcctgg agacaaaaag tccgattctt ttcgttattc ccaggaaaaa
    15781 gggttatagc tatcgaaagg aagggatcgg gcccattggt gaaggggaga ggggggcgtt
    15841 catcatcggg atgggtgaca tgatcatgcc ttccattctc gtcgtctcgg caaacgtgtt
    15901 cctcgcgacg gcggcacgga tagggccggt caccatcccg gcccttggtg cgatggcagg
    15961 ttcggtcgcc gggctgtgcc tgctcctcgt cttcgtaaaa aggggtcgac cgcaggcagg
    16021 tctcccgccg atcaacggcg gcgcgcttgc aggattccta ctcgggtacc tcgtgtctct
    16081 cctcgtgtga ccttttccgg aatgcaagga ggtgttcaag cacctccgtg acaccctcgc
    16141 cggtctctgt cgacatgttg atatacccgt cgaaatacgc gatatctgcc ttgttgacaa
    16201 cggggacaac cggaacggag accctctcct ctatctcgtg gaggagcctg aactggtcct
    16261 cgagtggata cccgcattgc tcgctggcat cgaggatgac gaggatgacg gaggcgaggt
    16321 tgaccatcgc tgtcagggcc tgccgttcga tcgcgctccg ctcttccgcg gggcgatcga
    16381 ggaccccggg agtatcgatg aactggacac gttcccggtc gataacgcgg tgcccgacga
    16441 tgatgccctt ggtcgtgaag gggtatgctg cgacttccgg tgttgccgag gagacgagac
    16501 ggatgaatga tgatttcccc acgttcgggt accctgccac gacgacagtg aactcgtcgc
    16561 tcacatgggg aagtgtccgc aggatgttcc tcacttcgtt gaggaagaca aggtcatctt
    16621 caacctggtg gaccaccgat gcaagccttg ccaccgccct cttccggatt cgtgccggaa
    16681 actcagattt tctcgtctgg tacgcaaggc ccggaccgtg ggtccgtgcc caccgggctg
    16741 cccatccaac ggaaccaagg gctttcctga ccttcccgat accccacatg atatcgacga
    16801 tatccctgta aaatgcaggg acggaatcga agtcaggaaa tgactgcatg accctgacga
    16861 ggcggtcgtg gatggcctgg gagactgccc ggacaaactc ctcgtttgcc ctgtccttgt
    16921 tcttcttgag cttcattctg gatgcagccc gccggaagct cctgtcgagt atctcgtcgg
    16981 cggtgggcac cgtgggaatg ctctcgaatt ccactttggc tctacctaat ctatatatgc
    17041 ccatgcagat gataaaccat tatggatttg tccctgatcc aaaaagacat tttaatcaca
    17101 cttatttcgc tctatcacaa gcattctcat cccgttaagg gggaggagat cgcggaagtg
    17161 attcgcagga acccggggac tgtccgcaac cagatgcagg ccctcaaagc gatcggactg
    17221 gtcgacggga tacctggtcc gagaggtggg tataatccta ccgcacaggc atacagggca
    17281 ctgaaccttg acatttccga gaaagaatac gacgttcgga tatcccgcaa cggcgaggat
    17341 gtgccggggg tcaaggtcgt ggagattgca ttcaccacgc tctgtcaccc cgatatctgc
    17401 cgggcaaatg caaccatacg gggctccgtc aaggcttttg agatcgggga ccagataacg
    17461 attggcccga cacccgtgaa caagctcctg ataaggggcg aggtttatgg cagagacgag
    17521 gtctcccaga cgctcctcgt atccatctac gagatgatct ccctgcccaa gaaacccatc
    17581 aggtattaca tgagcagccc gctgatctcc ctgaagagaa cagatgcact gggcgatgcg
    17641 ctccaccttt tcaatgccca ccgcatccgc ggagcccccg tgatcgaggg ggacaccctc
    17701 tacgggattg tgaccatgag cgatgtcgcc cgtgcaatcg aggacgggat acccatgaca
    17761 acgcccgttt ccagcgtcat gacgaccgat gtggtgaaag caccgtccac ggtccagctc
    17821 ttcgaggtca tccggagctt caaggagagg gacatcggcc gcctgatcgt gatggaaggg
    17881 caaaaacccg tcgggatact gacccagtct gacatcatca aggtcttccc ctctctgtaa
    17941 tgggattcag gatctcaaac ccggttggta acggtctcgt ttttccctcg caggatgacc
    18001 cgctgtcaca atccggggtt tttaaacagc tttatatatg aatagggcca caccctcttt
    18061 tatgtcgaga gttctggccc ggagcctttc caagaaaaag atcgtgacca acgagggaaa
    18121 agtcattggc acgctgaaga accttgttgt ggacttcgaa acaggtcagg tggtcgacct
    18181 tgtcatctac cctgatgcgt cctttgacac gaccgggtac cggaccgagg gtgaccgcct
    18241 ctacatacct ttcgaggctg tcaaggacat caaggattac atcgttgtcg accgctacct
    18301 gtcgaggaaa tgagaaaaat accggtccag ggcctccaca aaaccatccc cgtactcctt
    18361 ttccgtcact tcatcggcat ggtcctttaa ttttgggtgg gcattcgcaa cggcgattcc
    18421 tgttcctgcc ctctcgagca tgtcgatatc gttctttcca tcgccgatgg cgaggaaatc
    18481 acgggtctcc atgcccagca atcccgccag ttttgtgaat gcagcaccct tactcacgcc
    18541 cggcgggtgg atatggatgg caaaacccgt gtcaaggaca acgacgggat ggtcgcggag
    18601 gatctcctcc acgagggaga cagggagcgt ccgggcaaac gcaacatcga cgaacctgta
    18661 ggggagactg tagtgttcga tcccgatacc cctcttcctg caggcggaga ccagttccca
    18721 gagcgcgatc cggggtgccg ttccatcggc cagcacggaa agatcgtggt tccacccggg
    18781 cctgattatc cccccgtttt caccgatgta gatgcctcct gtcccggaca tcttggagaa
    18841 tgcgtccatg aaacacgcag tattcccgct cgcgagcacg acgcagaccc ctgcatcaac
    18901 gagattgcgc attgactcga ttgccccggt gtgaacacgg cgccgggcat cggtgattgt
    18961 cccgtcgata tcggtgataa gcccccttaa ccgacgcgga ctggacatgg attcgtcacc
    19021 tggaagaagg ttctcctcct ggatcattat gccttccgcc cggggaggaa gacgtggtac
    19081 gtgcacggac aatgaattgg catccgggca ggtctggttt ttctcccttt ggaatgtgca
    19141 aggatggcta aaaaaaaaag aggtcaggcc tctttgagac ccgattcttc gaccatgaac
    19201 gcagcctcgc cctcggggag gttgggactg tcgacgaggc gggcaatacg tttccctccc
    19261 ttgctcttgc gcaggtatat ccggaacgtg gccgtgtggc ccacgatgtt accgccgatg
    19321 ggtttcgtcg ggtcgccaaa gaagaccgcg gggttcgaga ggacctggtt tgttacaagt
    19381 cccaccgcgt tgtgctcgtc gacgatcctg aaaagatcat ggaggtgacg gttgagtttc
    19441 tgctgtcgtg ctgcaagggt accgcgtcct gcatactcgg ccctgaaatg ggccgtgagc
    19501 gagtcgatga tgatcagcct gaccggtctt tcagaatctt tgagttcctg tgccttctca
    19561 cgggcgctgt ccatcatgag catctggtga tcggaagtgt gtgcccgggc gacgtggatg
    19621 ttttccagga actcttcggg atcggcgtcg ataccaagac cgagtaccat ctgctcgata
    19681 cgctccgggc ggaaggtgtt ttcggtgtcg atgaagatcg cagaccccat gagacctcct
    19741 tcctcctcgg ggagctggac gttgactgcg gcctggtgcg ccacctggct tttcccggaa
    19801 ccgaactcac cgtacagctc ggttattgcc tgggtctcga gcccgccgcc gagaagtgcg
    19861 tcgagctcgg gcacgcgcat tttcagtttc cttacctctt tcctctgttc gaagacatcc
    19921 tttcccgtcc ggaaaccgcc gaggtcaacc atttccctgg ctgccttgat catctttttt
    19981 gccgtggatt cacctatctc ggcagtctcg gcaagttcct ggggcgatgc cgtggcgatg
    20041 ctctccactg tgaggaatcc tgcttcacgc agtttctcgg cggtacttgg tcccacaccg
    20101 gggaggtctt caatttcaag ggatccggaa ctcatcggtc gttcaccttt tatggagaga
    20161 ggatctcact cacctgcata tatcttcata gccgtgcggg gtgaaagtat ccgtctctgg
    20221 tacggggccg gtgaacctct cgcatctctt cagcagtcct tccctgtccg ggacatgctc
    20281 ctcccaggaa agaatgctga tcctttttcc catgcggagg acctgtgcct ttatcgcgtg
    20341 gccatgggga agatccctgc cggcaacgat gaagcagtcg gatccggtat cgaggtaggt
    20401 ggaaccaccc gtgacaatga catctccgca tatctcctct tctgcaacgg gtgaagggat
    20461 gggcaccctg atcaggcttc ccctgccggc atggatctcc cactctcccg tctttgcctg
    20521 ccggacggaa cagaggtaaa ggcccacctg ttctccgggg agaaggggta ttttggcatt
    20581 gtctccccac aggacaaccc gtgcatcggc agtcccgtcc gtgatggtaa ttgtgcggac
    20641 agatgaagtc ctgccgtccc gggtcacaaa agaccgggcg ggcgggcacg agatgacagt
    20701 cccggtcacg gagcaggtct cttttcccgc aatactgccg agggggtcag gagcagcagc
    20761 catctccccg tccaccggtt caacggtgct cttctcgtcg atgctgtatt caggtccgtt
    20821 cttccggtat ttttcgagag ccccccggat cctgaaggag gcaccctcca ccatgtcacc
    20881 catgagttcg ggcacccagc agaccatgcg ggaaatactt tttccgtcac tgaccaccat
    20941 ctctaccatc tctgcctcgc tcccgtcttt ccgggcgacc ttccgggctt cgccgatggc
    21001 gaggatgcag atggtgatgt cctttctccg gggcggggcg aggtatggtg caacctctga
    21061 cggtcccgaa atctcgacgg gggcgggtct cattgccatt acggttatct cgcccgggtt
    21121 cctgccggca tgcctcccga tgacctcgag gacgtctccg atcccgatgt cgtggcttgc
    21181 ggctgccttc tcgtcccaca ggattgcccg cacctggccg gtctcgtccc cgaggatgag
    21241 gcttgcgaca agccctttct cgccttccgg tcgttcaaat tcccggacgg gattcttggc
    21301 gatgaccttc ccgaagaagg aaaaaaggct ctgctttccc cccaaccgcg caatcttgac
    21361 gtggtgtcgg ccgaggtcct ggacgaccat catggcagcg gtcacctcgt cgacgaggtc
    21421 accgcaggcc tccatcttct cctctacctt ccgctcgaat tcttcccggg agagcaggtc
    21481 atccacgagc gcatagtgga actgcacgaa atccctttca cctcattcct tctgccacgg
    21541 cgggatctgc atcgttgcag tcaggtcttc aattgtctct gccctccgca tcagcgccgc
    21601 ctcgcccccg tgtatgagga cttcggcaca ccgggggcgg cagttgtact gggacgacat
    21661 gcagaacccg tatgccccgg tgtccaggat ggcaagcagg tcaccggccc cgatgggagg
    21721 aagcctgcgg tccgaagcaa ggatatcccc gctttcacag atggggcccg tgatggtata
    21781 cgtttcggac ggtggcatgc ctgccctgcc attgacaacg acctcgtggt aggaatcgta
    21841 catggccggc ctgatgagga gattgaaacc tgcatcgacg ttgacgaagt ttttgtgtgc
    21901 tttcttgaca gagttgaccc gtaccaggag tatggtcgaa tctgcaacga gataccgccc
    21961 cggttcgacc cagagcgcgg ggttaatacc cagttcggtg gaaacgtccc gtatcggggg
    22021 tatgatggca gatgcatagt cagcaggtgt cggggcccgc tcttcctcgt aatggtggta
    22081 ggggattccc agcccccctc ccaggtcaat gaactcaagg gtgaccccca tcctgacaag
    22141 gtcgcgcacg atctctgcca tcacccgtgc agtctgcgca aaaggttccg ttgcaaggat
    22201 ttgagagccg atgtggcagt ggataccaac gggctttaca cccctgcagg cgagggcctc
    22261 ccggtaggca tcgcgaatcc tgtcgtgggg gatgccgaac ttgctcgtcg caagccctgt
    22321 tgcaatcttc ctgtgcgtcg ggacgtcgat ggccgggttg acacgaaacg cgatttttgt
    22381 ttccttccct ttcttttgcg atatccggtc aagctggcgg agttcgtcga aggagtcaac
    22441 ggagacggta acacccgatt cgactgcgag cgagaggtcg tcggtgctct ttgaactccc
    22501 gttgaagagc aggtcaccgg gtgccatgcc tgccgagagg gcgagccgga gttcgcccgg
    22561 ggaaaagaca tccgcaccgg caccctcgcg ggcgagtgcc cgcagaatag cgagattccc
    22621 gttggccttg gccgcataca ggacttttac ctttgggtaa cgggatgata gttcatcccg
    22681 gaaggatcga aaaagggaga cgatacggtc ctggtctgtc acgtaaaggg gtgtcccgta
    22741 gcgggtggca agtgtcgcac agtcaatccc gccaattgcg agctgccctt ccctgatcgt
    22801 gaggtggggt ggcaggttca taatcccata tcctccatcc tctccagtgc ttcgcggata
    22861 cgctccgtgg atcgcgtgaa ggcaaacctg acgtacccgt ccccgcctga tccaaaccct
    22921 ataccgggtg tgacgacgat ccctgcctcg tcgagcatcc gcgttgcaaa tgccatgcag
    22981 tcatcgacgg gcatccagac atagaaggtc gctttgggtg gttccacgcg aaacccaagc
    23041 gcccgcagtc ccttgacgag ggtgtccctg cgttccctgt agatgctgca cgcctgtgca
    23101 acacagtccg gggggcccga gagtgccgcg atggctgccc tctgcaccgc gtcaaagacc
    23161 ccggagtcaa cgtttgtctt gacccgcccc agacccgcaa ggatttccct gtttccgacc
    23221 gccatcccta tccgccagcc ggtcatgttg aaagtctttg agagggaatg catctcgatc
    23281 gccacgtcca ttgccccttc cgtcgcgagg aaggagggag cacggtaacc atcgtaggag
    23341 atctcggagt aggcattgtc atggacgatg atgatatcgt gttcccttgc aaattcgaca
    23401 gccctctcga agaacccggg gagtgtgact gccgcggtgg ggttgttggg atagttgagg
    23461 aacatgatcc tcgcagcatc cgcaatatca tcaggaatgg catcgagatc cggtatgaag
    23521 ccattttctg cgcggagcgg catctcgtaa acccgcccct ctgcaaagag cgtggaggtc
    23581 cggtagacgg gataccccgg gcttggaaca aggacgtaac tgccgggatc cacgaaggct
    23641 tccgggatgt gggcaatgcc atcctttgat cccatcagtg caaggacctc tgttgccgga
    23701 tcgagggtaa caccgaaacg atcaccgtac caacgggcga ctgcctgccg gaagccgggc
    23761 atccccgcgt acgacgggta atggtgattt gcagggtccc ttgccgcccg gcagagttcc
    23821 tcgaccacgt gggggggcgt tgcaaggtca gggtcaccca ctcccagatc aatcacatca
    23881 cacccttccc gtatcttttt cgctttgagt tcatcgatac gggcgaaaag gtagggaggg
    23941 agttttccca tgcgttccgc gtacatgcgg gaaaatattg gccctgaccg ctcattaagg
    24001 attacatggg cgggagggga tccccctgcg ggcttgccgc acggatggaa aattccattt
    24061 ttatagcggt ttctgatgat ccctcaccag ccgttacccg gaagggtaaa gaccgggtaa
    24121 agaacctata agtgaccggc ccacccacgg cattacacgg gtatttatct gcccggtcgg
    24181 acggaagtgt ctttcatgag tctggaggaa gcagatcccg tcagggttat actgacgaca
    24241 gcaggcaggg acaagggccc cgagatcgcg cgacaccttg tcgaaaagcg gcttgccgca
    24301 tgtgtcaata catcggatgt aacgtcctgt tacaggtgga agggagagtt ctgctgcgac
    24361 caggaagtcc tcctcgtcat caagacaacc ctttcccatg tccgcgacgc cctggaggag
    24421 ataagggcca ttcatccata cgaacttccg gaaatgattg tccttcccgt tgaagggggt
    24481 tatccgccct acctcgcatg ggtgagggag gagactgcgc catgaccgtg accaccgtta
    24541 agggaataca ggtcagggaa ggcaggataa tcgagataga cgatccggtc atccaggaag
    24601 atcgcttttc cctttgcatc aacggggagt tctatgcccg catcgtggcg agcagggacc
    24661 aactcagaga actcggtgcc gggttcgttg tttcccaggg acttgcacgg gatgtcgggg
    24721 acgtgatcgt aaaaggggac gagatagatg ttttggcatc tgttgctgac ggtggtggca
    24781 gagaggtgat atcgaccggc gcgatcggtc tctctcgccc ctttgaaaag gtcgtctcgc
    24841 cgctcaccct gaccacacgg gatgtgtatg ccatcacgga ggagatcgag acggaggtgt
    24901 ggcaccagac aggtgcagtc cactgttccg tgctctcctt cgggggccgg gtagtggcac
    24961 gttccagtga tgtcggaagg cacaataccg ttgacaaggt catcggccac gctgtcctca
    25021 acaggctgga caggtcgcag tgcgtcatcg gatgcacggg gaggcagccg cgggacatgg
    25081 ttacgaaggc tgcccatgcg ggtatcccga tcgttatatc gagggcagcg tcaacgaaac
    25141 aggggatcga agccgcctgg gaggccggga tcacactggt ctgtttctcg cggaaaggca
    25201 ggttcacggt atattcgcac cccgggcgca tccgtgaact gtccgggatg gtcctgtcac
    25261 caccatcccg tgcaggagac atgccccggc aggaaaacag ataagaagcc cggtcccacc
    25321 agtcatcagg agagggaagt ggtatttatc acaggacaga aggaggaaaa agaagccgtt
    25381 ctggttctcg gctgcccgca ggtccctgtc cagaccgccg tggcgctgta tctcatgcac
    25441 ggcctgcgaa ggcttggtgt ccggccgatc gtagccggaa accctgcggc aagaatgctg
    25501 attgacgtct cagatcccct tcaccactat gcaggcgaaa tggtcgatct cgatacgttt
    25561 atcgccgaca tggcagccgg aaggagaaaa catgactact atatcgtctt tgcgcacaac
    25621 gacgcgggag taacgtatgc tgcgacggtc cagtccatct cgggaaagaa ggttatcatg
    25681 atcatttacg gggaaaattt tcaggctatc gcggacaggg tcgactttcc cgccgagaag
    25741 atcatggcaa aggcggtcca taacccgatg cccatgaaaa agaagatcga cgaggtgctc
    25801 ccgtggcttg tatcgaatct ctgaagtacg aaatcatcct ccggaatgcc acgttttccg
    25861 aatgcaggga atatatccgg aaaaactgca gggaactcgt aacggttgat cccggttttg
    25921 cactctttga aaaacccgtg attggagttc ctcccattct tcttggactc gatggagatt
    25981 cgatcacctt tccctataca aaaccctgtt acgggacatt ccttttgaga acggagaacc
    26041 cggaagaagc cgcaaggtta aggtcccttt tgaaaaaata ggcggggagg gtttccagga
    26101 gttttccctt cccctgcccg gcaccctgca atacccccca agaaggtata tcaccccccc
    26161 acgggagaat cataccatcc agtgatatgc catgacggag atgtcagtgc tcgtaggggg
    26221 aagagcagga gacgggataa acagtgcagg cctcattatt gcccacctac tctcccgtat
    26281 aggatacagg atctacatgt actttgatta cccctccctg atcaagggcg ggcacaattt
    26341 tgccatcatc cgggcatccc cggaaatgaa aggagcctgc cgccgggagg ttgatttcat
    26401 cctggcactc aaccaggaca ccctcgacct ccacagggac cttgtccggg acaggacaac
    26461 cgtgatatgt gacagttccc gtgtaaaagc caccggcata tgcatcccca tccccggtat
    26521 cctgaaggag gagggggcac cagccgtcat gggtaactcg tgcatcatcg gtgcttttac
    26581 ccgcgccgca ggcatcccgt gggcagtcct cgaagaggtg ttctcccggc acctcaggaa
    26641 gggtctcgaa ctgaacctga aagttgcccg gaggggttac gaaatggcca gtgaccattc
    26701 ggtaatccct gcgggggatt ccccggcact ccccatcctg tcgggaaacg aggcgattgg
    26761 tcttggactc cttcacggtg gtcttgatgc ctacgttgcc tacccgatga ccccgacttc
    26821 gaacctcctc cacttcctgg cggatatcgc agaccgggcc ggccttctcg ttttccatcc
    26881 ggagaacgag attgcagtga tgctgatggc actcgggctc ggttatgcag ggaaaaagac
    26941 agccgtcggg acttcggggg gcgggttctg cctgatgaca gaaggtctct cccttgcagg
    27001 cgcaaacgag gtgccggtcg tgattgttct cggtcagcgt gccggaccaa gtaccggcat
    27061 gccaacgtac acgggccagt ccgacctcca ctttgctctc catgccgggc agggagagtt
    27121 cccgcgcctg gtcgtagccc cgggagatcc aaaacaggcc ttcacctgga gttcccttgc
    27181 cctccgcctt gcgtggaggt accaggtgcc tgcactcatt ctctgcgaca agacgctctg
    27241 cgagggatac tacagtttct cctcccctgc agcatccgtc ccccgtatcg acgacgccct
    27301 ggcaggaacg cctgggcctt cctacaggcg gtacctcctg acagatgacg gggtgagccc
    27361 ccttctcttc cccggcagtc ccggaaccgt catcaaagtg aacagctata cccacgacga
    27421 ggccggaatc acgacagagg cagcggaaat ggcgtccctt atgacagaaa agaggataag
    27481 gaagggcaag gccctcgaga acggactcct tgacctgccg gtgatcgcgc agtcaggtga
    27541 cacgagctcg gataagactc ttgtctgctg gggatccact gccggtgtct gcagcgaggt
    27601 ggggccggaa ctcgggttca gggttatcca gccagtcgtt ctttcgccgt tccctgcgga
    27661 aaagttcctc cgggccacac ggggaacgca tgagatggtc gtggtggaag agaacgcgta
    27721 cggccagctt gagatgctcc tgaaccggtt cggagtgagg gccgatgcat ccgtccgtaa
    27781 atacgacggg cggccctttg ctgtcgagga actcagggcg cgtctcatgg aggtggtgtc
    27841 atgagcgcaa gggacttcat cacggatgca cagaacacgt ggtgcccggg atgcgggaat
    27901 tttgtcatcc agtttgccct gcgcgatgcc atccggtcgg ccatagaagg cggcctggac
    27961 cctgactcca ttgtcctcgt gacgggaata gggtgccatg caaagatggc cgattacctc
    28021 aatatcaaca gtttttactc gatccatggc cggactgtcc ctgttgcgac ggcaatcaag
    28081 atggccgacc ctgatctcca ggtcatatgc tgtgcgggtg acggtgatgc ctatgccgag
    28141 gggctcgacc acctggtctt tgcagccaag cggaacagcg acatcaccgt gatagtccac
    28201 aacaacaggg tctacggtct tacgaccggg cagtatactc ccacgtcgcc gagcgggttc
    28261 cgggggcgtt cgacgcccgg agggacgaag gaggaacctt tcaaccccct cgaaatcatg
    28321 cttgcgtcgg gggcaacctt cgttgcacgg gggtgcacga ggaagaggaa ggaactcgaa
    28381 ggggtcatca gagagggaat catgcacagg ggcttttcct tcattgacgt gttgcaggtc
    28441 tgtgcatcgt atttcaacca gacggacgtg tatgacaggg ccgtgtacag cctggaggga
    28501 catgacgcgg ctgactttga tgctgcgtgc aggaaagccc gggaatggga ctataacagc
    28561 gattccccga ttgcaatcgg gacgtttttc agggtgatac gccctacgct cgaggaacga
    28621 ctgggggttc cccggaaaaa ggaggggacc actgaagaga ccatcgcaag gatcctcggg
    28681 gaacggaaat gagggtctgc atgggaatat cccgaagaat cctccatcgc gggggaaaag
    28741 ggatcgaaag tgtacttttt ccctctcttg tacaggttgg aaagggaatg gcaagcaaag
    28801 ccgtatggat ggatgaatct catggttgaa tcaaacctct ttgaatcagt caaaaagaac
    28861 ctctgctcct gttctgcaga cctcgccctc gatgagaata tcgaggcact tctcaagact
    28921 ccgcggcggg aggtatcggt ggcaatcccg gtacggatgg atacgggtaa gatccaggtt
    28981 ttccagtctt tccgtgtgca gtacaacgat gccctcggac cgatgaaggg gggaatacgt
    29041 taccacccgg atgagacgat agataccatc aggggccttg cggcaatcat gacatggaag
    29101 tgtgcacttc acaatcttcc cctgggaggc gcaaagggcg gggtcatctg taacccgaaa
    29161 gccctgtcag aacgggaact ggagcggctg agcaggtctt acgtccagga gatgtttccg
    29221 tatatcggtc ctgaccgtga catacctgcc cccgatgtct acactgatgc aagggtcatg
    29281 gcatggatga tggatgaata ttcccggata gcgggaaaga caacttttgg atcattcacc
    29341 gggaaacctg tactcctggg agggtcggag ggaagagggg aagccacggc cctgggaggc
    29401 tggtatgcca tccgggaagc aatgcacagg cgggaaaggg acttttcagg catcacagtt
    29461 gctgtccagg gatttggcaa tgtcggggcc catgcagccc tcctcgggca ggaattgttc
    29521 ggggcgcggg tggtggcagt cagcgacagc aggggagcaa tctacaaccc cgacggtctg
    29581 gcagtccggg atcttgtgga acacaagaaa aaaacaggga gtgtgatcag gtttccgggc
    29641 gcaaccaaca tcccgggcga agagattctc acgctgcccg tcgatgtcct catccctgcg
    29701 gcacttgaaa atacaataac ctcccggaat gcagaccagg tgagagcggc ggtcgtcgcc
    29761 gaattcgcaa acggtcccac cagccacgag gccgatgaga tcctttttgg atcgggtatc
    29821 acggtgctcc ccgatattct cgtgaatgca ggaggcgtga tcgtctccca tttcgagatg
    29881 atccagaatt tcacgatgga tcactgggac agaaacaagg ttgcccggaa actcgaggga
    29941 aaaatggttg gttctttcaa aacggtcagt gaccttgcgg agaacaacaa cgtctctctc
    30001 cggaaagcgg cctataccct tgcagtcgga cgggttgccg gtgcgatgag gctgaggggg
    30061 tgggcctgac acgcggtgca ggcccaaaaa aagaaggtca tggtcagacc cccttttctt
    30121 ccgggcagct atgctctctt ttcggcgctc tttccggatg agaacgcctt ttcctctcgt
    30181 ccacgggcaa cgagactatt aatgcatccg gaggagacct catgaatggt ctgcttcatg
    30241 tgggaatttg cggtctccgg tgacctcttt gcatgggtgg tgctcccctc cctcatcttc
    30301 atggcgcgga tatgcgatgt gagccttggg acgctccggg tcatcttcat atccagaggt
    30361 tttaaaaggg tcgccccctt cgtcgggttc ttcgaagtga tcatatggct ccttgccatc
    30421 ggccaggtga tgcagaacgt ggggaacctt gcctcgtaca tcgcatatgg agggggattt
    30481 gctgccggaa cctacgtggg catggcagtc gaggagaggc tgtccctggg caacgtggtc
    30541 atccgtatca tcacccagaa ggatgcgggc cagctcgccg gggcattgcg gaagatgaac
    30601 gtcggggtca cgacgatgga tgccacgggc gcgaccggcc cggttaccgt cctcctctcg
    30661 gtgtgccgca ggcaggacct tccacgggtc ctgtcatgca tcaatcgtta ccacccggcc
    30721 tctttctaca cggtcgaaga ggtcaagacc gtaaaggaag ggatcttccc ccgcggccgg
    30781 ggagggattc atataaattg gagagacccg catgggtttt tccggaaagg aaaatgaaga
    30841 ccggatatta ctttttgtat ccggtatccg gacagggtca tcgtttctgg gcgattccag
    30901 gtgctgacac ctttgcagat gctctcactc gagcatgaca agcccgatag agatgatgtt
    30961 cccgtgctcg atcatcccgt attcgaggtt ccggcaggga acgacatgga gttcccagcc
    31021 cgcgttcctt gcagttgaaa aaacatcgat gcctgctgcc tccatgcttg gccggacgag
    31081 atccatgtgc cggcacatgc ggcggatact ctcatccacg gtgccgggct gctcttctgc
    31141 cacgcagtgc tggtgctcgc agtagatgca gggatatgct ccaaagccga atgcctttgg
    31201 aaagtcgtgg taaaaggcag ttttttcaag gaaatgaacg gtgccattga cccagaggat
    31261 aaggtcgcgg aagaaagggt gaaagtcttt tggaatcttg tcgggagaga tatccgggtg
    31321 tcccggaatg ccgtcgaacc ggaggaggag cccggtcgaa tattctgcaa tcatcttccg
    31381 tgtttccgct ggtgccggtg cgtagggagg gcagctcatg tgctttccat accccttgca
    31441 cccgaaccgg cacttgaacc tcacccactc ggcgacaacg atatccctgg attggatggg
    31501 ccgggcaagg gcacccttct cccctgcaag gcgggtgagt gttgcgatct ccccgtccag
    31561 tctcggattc atctgattcc ccggaaaaaa cactattccc ggtcctgacc aaaaaggtat
    31621 cgcggccctg cgaaacgaag atatcgaaga cggacccaaa cgtcactgct gtgaacatca
    31681 aaagggcccc ggggcgggaa aaagaaatga ccgtgggtgg gaggacgttt tctctccgta
    31741 tgcaggagga agatctcggg gatatctacc ccgggatggt tcgctattct gttgaactat
    31801 gggaaaaaga ggggctggtc gccgtcttcc gcacgaattc ctttgaatac gcccccacca
    31861 tgacctatgg cgcaagagag gccgcagaaa gggtattttc cagctgggag agggaccttg
    31921 ccggtgacat cgagggtttc ctggaaaata attccctgcg ggaaccgatc ccgtaccagt
    31981 ccccaccgga aactcccggt gttgttgtca tccagggcag tccccgaccg ggtggaaact
    32041 gttccatcct cgcctcgtgg accgcagacg aggcacagca gcttggaaaa cccgtgtgtg
    32101 ttgtctttcc gcacgatctg gacattcacc cctgcatcgg atgctaccag tgctacaaca
    32161 cgggcacgtg cgtctacgag gatgacatga actccatcat cccggccgtg gaaaagtgtc
    32221 gcctgctcgt tgtctgtact ccggtctata cgaacactgt cccggcgggg acaaaggcac
    32281 tcctcgaccg gttccaggcc ctccacgcgt caagaactct cggacgacga ccgtcccgcg
    32341 ggacgagggg gcttctgttg tcggttgcgg ggcggaaggg aaaggaaaat tttacatgcg
    32401 tgtcccgcgt tgttggtgcg tttttctcgc tcgttggaat cagtgcggaa aaacccgtgc
    32461 tccttgacgg aatggacgag acacgggata tccgcgttat ccccgggctc gaaacaaggg
    32521 tcagggatgc agtcaggacc gccctccgca aggactaggg aaagttctgc ccgggaaata
    32581 agttcacccg atgctcatga acgggcatat caagggatct aatatgtttt acgtctctgg
    32641 gagaaccacg tgttctttat aaatcaaggg tcctgtcacc ggaacgctgg atgaggtggg
    32701 gaccgtcctg ctggggatcg ttgactgctt ttgagacagg gtaagcctcg aggatatcat
    32761 cagggcaggg tgaaaggatt gcctttctct ctccctcgcc gatgggtccg ggggcaatcc
    32821 agcgggcctc gtcccgtggc tgcaggattg cgggcatcct gtcgtggaac cgtgccacga
    32881 gggcgttcgg ctccgtcgta atgattgtga aggtccacag tggcgggtcc cttcccttca
    32941 ggatgtcgaa gagtccggca aatgcaaaga gagcctggtc cttcctcctg atgtagacag
    33001 ggactttctg cgttccggac ttctgccact cgtagaaacc ggtggcagga acgaggcacc
    33061 ggtggcgtgc gaggggaccg tggaaggacg ggcgttccga cagcgtatcg gcacgtgcat
    33121 tgatgatggg acgggcacca gtcaggtccc ttgtccacga ggggaccagt ccccaggtca
    33181 tcatcctgat gaccctttcc ccggtgtggg tcgcataaat gatcgggacc tgctgggagg
    33241 gtgcgatgtt gaaccgtggt gaaagagaga gacccgtatc gtccacgccg aagcgctctc
    33301 cgagcccgac tgtcagggca agcgtgaatc tgccgcacat ggatatccct gctccatctc
    33361 ctgtatcctg atgctgtcaa tgatcgggag gacctgtccg agggagtcta tcgcgaaatg
    33421 agccccgcca ctgtcgcctc tccgcgaaaa ccggtccccg tagcgtgcat ataccgttat
    33481 catccccatc tgcctgcagg gggcaatatc cctccgcggg ctgtctccca ctgcaatgac
    33541 ctcgcggggt ggcactccga gcagtttcag ggcgtactgg aaggggaccg ggcttggctt
    33601 tttctgccat gttgcctcgt gtgtcacgat atggtcgaac agcccgatga gatccgtttt
    33661 ttcgagccgt gatacggctt ccggcctgtg tgcatccgta acgagtgcaa ggggataccc
    33721 ctgctcccgg agtgcaccga gggttttttg cacgccgggg taggggtgga tccgggcaag
    33781 tttcacctcg cggtacatgc gggtgcagcg ggagatgagg tcgggatcag tcattccgtg
    33841 gtcttcgagg aaatcgcgta cgttttgggg atcctcaaac cccttctctt tgcggaggaa
    33901 gtaggagaag agatcttctg cttttccgca cccggcctcc cgcgtgattg ccatgcaggc
    33961 ggcatacttg gcttcaacga ggtcaaagag ggtattgtcc atgtcaagga ttacagccct
    34021 gacccggttc ccgtatgtcg ttgcactcat cccactacac aatctctctt tgctccttat
    34081 ggaagtattg tttgggagat cttccccgga ttcccctgtg caaacggtca atatctcctg
    34141 cgacacatca ccctcttgcg aggggttgaa cgcataatgt tactccacaa gatccgatct
    34201 gaagggctct cccattactc gtacttcgtt gcagacggtg ggcaggccgc cgtcattgac
    34261 ccgcgaaggg actgtcaggt atacctcgac cttgcctcat ccacggcgtc ccggataacc
    34321 catatattcg agacgcacag gaacgaagac tatgtctccg ggtcttgcga gcttgcagaa
    34381 aggacgggtg ccgccattta ccatggtgcg gcactcgact tttccttcgg acgacctgtt
    34441 tcggagggtg acaggtttcg catcgggagg ctggaacttg cagttcttgc cacaccgggc
    34501 catacggccg agagcatttc cctcgtcctg cgggatctct ccatcccggg cgaccccctg
    34561 atggtcttta ccggagatgc cctctttgcc ggcgacgtgg gaaggacgga cctctttggg
    34621 ccaaaaaagg cagaatgggc agcagggacg ctctacgacg caatccatga gaagatcctg
    34681 ccgcttggag acggggtcgt tatccttccg gcacatggcg ccgggtctgt ctgcggtggg
    34741 gatattgccg acctggaatt tacgaccatc ggctatgagc ggacccacaa cccctgtttc
    34801 ctgctggacc gggagacatt tattgcaggg aagaaggccg agcaccatta caggccccct
    34861 tacttctcaa tgatggagaa gttaaacagg tcaggccccc ctgtcctttc ccacctcccg
    34921 cgtcccgttc ccctcgaccc gcagacactg gcggagaaga agaaggcggg tgcccagatt
    34981 cttgatacga gatcaccgga ggcattcggt ggggggcata tcccggggag catctcgctt
    35041 tggcgtgacg gtatcccggc ctttgccgga tgggtccttt cgtacgatca cccggtcgtc
    35101 atcgtggatg actgcccgga cgggctggat tccgcactaa ggcgccttgt caggcttggc
    35161 tatgacgcca tcgggggata cctggccggg ggttttgctg catgggcacg ctcgggaagg
    35221 gaaatccgga ggctggagac atggtcggct gccatgctcc gggatgccct tgaaaaggaa
    35281 cgattcatcc tgctcgacgt gagggaccgg aaaaacaggg aagcgatggg ctttatcatg
    35341 ggttcccggc acatttacgt cggcgaagtc cttccacgcc tggccgagat cccgaggaac
    35401 cagaaggtcg ttgtctactg cgatgcaggg ttcaagggga gccttgccgc aagcctgctc
    35461 cttgcagccg ggttcgacca tgtcgtcaac gttatcggtg gtttttcggg atggaaggct
    35521 gccgggtatc ccgtggagaa aaaaagtacc tgaagtggca tcgcagtctc ccgtaaaatt
    35581 cacaacgttt aataaagaga tgtatcaatc ctgaatgcgg tgaggtatgg agatagtgaa
    35641 gataccccgc atggagaaga aggaatacga taccctcatc gaaaagggtt atatctgccg
    35701 catcgcgttc cagggtgaaa aataccccta catagcccct ttcctctacg tattcgatgg
    35761 cagattcctc tacttccttt ccaccaaata cggaaagaaa ctggaatatt tcaggaagag
    35821 tccctacgtt gctgtcgagg tggaaaagta tacgaaagac ctttcgagct acacgttcgt
    35881 gagcatgcag ggatacctgg aagaggtcac ggattcgatc gacaagaagg tcatccgcaa
    35941 gcagttcgtg gatctcatca aggaacgccg cctttccaat aatatccttg ctgccctcgg
    36001 gcactctccc caggacccgc ctgaagcaat agcaaaggag gagcgttccc ttgtctggaa
    36061 actgacaggt gtcaaggaca tggtcgcgct gaaaaacctc tgaaaaacac tctcccatct
    36121 ttttttcttc actgctttcc gggcagataa cctttcagga gagattcgag gctgcctgca
    36181 tctgttatcg gattctggca cgactgtccg aggcaggcat gtgcccgcgg acccctgttt
    36241 tcccctgcaa gtaaggcaca ccagggcagc aaccggcaga tttccccggc atccggcttt
    36301 ctgccgagtg ccacggggag aatgaacggc gtgtaattcc tgtcaagaat cccgagcatc
    36361 cggacgtaga gagggtcagt ttcatctccc gtaacaacga ctgtcccggc ccggccctct
    36421 gtgaccagat gccccgcaaa aaacatcgtg caggaggagg gatactgcct gaccagagga
    36481 gggtagtacc cggctacctg cccggcccgc tccatgtaag aagtttctcc ggtcaggatg
    36541 tgaagacgga caaggttaga gaaggagagc gaattcgagg agggtatgga accgtcgagg
    36601 aattctttct ggcgcacagg aacgtctttc tggtcatcac gcgtccagta gtatccccct
    36661 ttatccttat cccagaagtt ttggaaatgg taatcctcaa gctcgattgc ggccgaaaga
    36721 aaggttggtt cacgggtggc caggaagaga tcgaggagac ccatgatgac cgatgcatag
    36781 tctgccgaca ttccctggat tgcggcatct cccgccatcc acctgtggta aatgcctccg
    36841 tccggcgagc gcatctgccc gagaacgaat cctgccgcgc gccgggcagc ggcgaggaac
    36901 gccggatctc caagggtccg ggatgcaacg gagagggccg atatcgcaag tccgttccag
    36961 tcggccagga ccagggtatc gcggggagga tgcggccttg tatttctcgc ggagagtaat
    37021 ttttctttca tggtttcgag gactctctcc acgtcgccgg gagccatacc aagaagccgg
    37081 gcagcgtctg caggctgccg tgctcgtgaa agtactcctg cttcacgggc actcgtgccg
    37141 ccggcagacc cgggcgtgtc tatgcaattc agcgaaaaga cagaagatgc gatcctgttc
    37201 tcttcagggg acaggacaga ttcgatctca tcccgggtcc acgtgtagaa caatccttcc
    37261 ccgcccccgc tgtctgcatc ttcaccggca taaaagccgc cgtcaggggc ctgcaggtcc
    37321 ctgcagatat actccatgca cccgcgtgca acattcccga gtacggcgtt tccggtaagg
    37381 gtatacgctt cggagtacgc aagagctgcg agtgcctggt catagagcat cttctcgaaa
    37441 tggggcacga gccagcgttc gtctgtcgca taccggtgaa aacccccgcc cagctgatca
    37501 tataccccgc cgcgggccat ggaaagaagt gtgtggcagg agagatcgat gggggcggtc
    37561 gtgcgatgga taatcccgta gcggaggagg aataggtgaa gatggaacag cgggaaccgg
    37621 ggaggaggac cgaatccccc gtttttgctg tcatggattg agacaaggtg gtcatagacc
    37681 atgcctgctg tgcctgcagg gagcggtccc gagtatgcat gatcccttgc atgcacgata
    37741 ttttccgaaa tgtcgcgggc gagagaaagt gcatcatcgc ggtgttcttt ccagtatgca
    37801 gcgatcgcgg caagtacctc gaggataccg taatttcccc ctgtccgggt cctcgggata
    37861 taactggtgg caaagaaggg gactcctcct ggcgtgagaa agatggagag cggccagccc
    37921 cctcttcccg tgaatgcgat acatgcgtcc atgtagtact ggtcgaggtc aggcctctcc
    37981 tcgcggtcga gcttgataca gacgaagtta tcgttcagga atcttccaac ctcgggatcc
    38041 gagaaagatt cctcccgcat cacgtggcac cagtgacacg tggcgtaccc gatagagaga
    38101 aaaatgggtt tatcctcttc ccttgcgcgg acaaatgcct cgtcacccca gggataccag
    38161 tcaaccggat cgaaggcatg ctgcctgagg tagggagaga cctcctttat gagcctgttt
    38221 tgtcccgggt cacccggccc ggcttttcgt ccctcttctg ccatgtattc cgtcacacct
    38281 gcacagggtg agatgggagg gccagtgtgt taaaagggat ggtggaggac acccatcctg
    38341 ttcccggggt acagggatcg ttacacataa cattccggcc cgtggagaga tatgggtaat
    38401 gagcagggat gatcagactc ccggtcaggc atccggcaca cggctgacac cggcgatggc
    38461 ccagtaccag gaactgaagg cgcggtaccc tgatacgatc ctcctcttcc atatcggtga
    38521 cttttacgag acttttggcg acgatgcccg gacactgtcc cgcgagctcg atatcgttct
    38581 tacgtcccgg tcgcgggata aggaaaaaaa cccggttccc cttgcgggag tcccctgcca
    38641 tgcagtcgag ggatacatcg cgcggcttat cgcaaagggc taccgggttg cggttgctga
    38701 ccaggtcgag gatccccgcg aagcgaaggg catcgtgagg agagaggtgg ttcgcgtcat
    38761 cacaccgggg atggtgatgg acgagacact cctcgaatcc cctgcagcca attatctcgc
    38821 ggccatcgcg ccgaaggaaa agaagaggcc cggcggaatg gcattcctcg atatcaccac
    38881 gggcgagttc ttctgcatgt ccctcccggt tgaaaacgag attgctgccg tctctgacga
    38941 aattgcccgg tacgctccgc gggagtgcat cgtcccggag aacctccagc ccgaactcct
    39001 cgaacatctc tccggcaaac cactgaccgt ttcgcgggta ccggcttcat ggtacgaccc
    39061 tgaaagcgca cgggtattcc tctgcaacca cctgggagtc tcgagcctcg agggttttgg
    39121 tcttgcaggg atggacggtg cggtcgttgc agccgctgct gccctcatgt atgccaggga
    39181 gacgcagaag caggatctcc ggcaggtgac aacactttcc gtccggcatg tccgggattt
    39241 ctgtctcctc gatgccgtca cgcagaggaa cctcgagatt ctccgcggga tcaggggcac
    39301 gggaaaggaa gggacactca tatccgtgct cgacaggacg gccacaccga tgggcagccg
    39361 gctgatgaga gagtggctgt gtgcacccct gctctcctgc gaggcaatca atgcacgact
    39421 ggatgccgtg gagttcatgg tgaggaaggc agcagtaaga atggagcttg cgcaggttct
    39481 caaacgctgc ggggacctcg ggagaatctc cggcaggatc gcctttggaa acgtctgccc
    39541 ccgggacctc aaaagtgctg cggacgcact cgaagttgtc ccccgcatcg tgggaatcct
    39601 cggtaccggg acaggtgaag gggcccctga actcattgcc ggtgcctgtg ggatgattcc
    39661 tgaccttggc tgggtaaaag atttgatcgg gcgggcaatc gtcgatgacc cgcccgcgag
    39721 cgtgaggaat ggaggtgtca tccgccctgg tttctgtccc gaactggact cgctccgcga
    39781 tctctcatca tcgggcaggg actggattgc agatttgcaa cagcgtgaaa gggagaaaac
    39841 agggatccgc tccctgaaaa tcgggtataa ctcggtgttt gggtattaca tcgaggttac
    39901 caggccaaac ctccacctcg tgcctcccca ttaccagagg aagcagacga catcttccgg
    39961 ggaacgtttc acgatcccgg aacttgccga gaaggaggca ctcatatcct ctgccgatga
    40021 acggcgcctg actctcgaac aggaggtcta ccaggacctt gtcaggcaac tccaggcagc
    40081 ggtccccggc ctccagtcca tggcacgcgg ccttgccatt ctcgacgtgg tctgttcact
    40141 cgccaacgtt gccgtttcca acaactactg caggccggtg gtcgacaact cgacgcacct
    40201 ccttatccgg ggagggcgcc atcccgtggt ggaagaaggg atgcagggga agttcgtgcc
    40261 caacgacctc gagatgtcag gggagaggga ccagatcctg atcattaccg gcgcaaacat
    40321 ggcagggaag tccacgtaca tgagggcggc agcgctgatc gtgatcatgg cacaggcagg
    40381 gagttttgtc ccggcggagt atgcccgggt gggaatcgtg gacagggtct tttcccgcgt
    40441 cggtgcattc gatgaccttg cgagcgggca gagcacgttc atggtggaga tgcttgaact
    40501 tgccaacatc ctcaacaacg tcaccggaaa gagcctcgtc atcctcgacg agatcgggag
    40561 ggggacgagc acgctcgacg ggctctgcat cgcccgtgcc gtcctcgagt atctccatgg
    40621 gggcagatct cacggacccc gcacgctctt tgcgacccat ttccacgaga tcgtctcgat
    40681 ggagggcgag ctgccgcggg tgaagaactt ccattttgct gtcagggaga cgggaaaaga
    40741 agttgttttc ttaaggaaac tgatcccggg tgcaacggac cggagttatg gcattcacgt
    40801 tgcatcgctt gcaggagtgc cacgccaggt caccgagaga gcacgtgcgc tccttgagga
    40861 ggagacgcgg ggaggagggt ccggaaggga gggtaaacca aaaaggtata cccagatgct
    40921 ccttttggat attgcgccgg aagtccagtc ccatccggtt ctcgaaaccc tgaaaaacct
    40981 caacctcgat gacatgacgc ccctttcagc tctctcaacg ctttatgagc tccagaagaa
    41041 ggcccgcggg ccgggtggga ggtaggagac atggaggagc agggaacagg cggaaagatc
    41101 cggcttctcg acaaagagac gatatcccgg atatctgccg gggaggtcat tgaacgaccg
    41161 gcgtctgtcg tcaaggagct cgtggaaaac gcgatcgatg ccggtgcacg gaggatcgaa
    41221 gtcgaaatca cctcaaaggg gggcaagatt gccgggatca gggtgaccga tgacgggtgc
    41281 gggatgacac cgcgcgatgc ggagctcgcc tgcgtccgcc atgcaacaag caagatcgcg
    41341 tctcttgacg atctcatgga ggtcagttcg ctggggttca ggggagaggc actcgcgagc
    41401 attgctgccg tctcccgcct tacactgata tcgagggcag gaaaggaggc ccttgccgga
    41461 atccggatac tatacgaggg aggagcaccc gttctgcggg aggaatgcgg atgcccgccg
    41521 gggacgaccg tggaagtccg ggatttgttc ttcaacacac cggtccgcaa aaagttcatg
    41581 cggtccctcg ctgcagagat ggcctacatc accggtacga tggaacgcat catcctctct
    41641 catcccggta tctttttcag ggttctccat aacaaaagaa cgcttatctc gtcgccaggg
    41701 ggcactgtca gggacgctgt actccacctc ttcgggactg actgcgaaaa gtcacttatt
    41761 ccggttcact tttccggccg ctccgtccgc gtggaaggtg tggtttcgcg accagccttt
    41821 tttcggcaga atccctacca gatctttgta tctgtcaatg gccgccctgt ccagtcccgt
    41881 ccgctcgccc ttgcggtgcg ggaaggatat ggcaccctcc tgccggcgga ccggtttccc
    41941 atggcagtcc tcgacataat gcttgacccg gagctcgtgg atgtcaacgt ccatccgacg
    42001 aagagggagg tacgcattgc ccgggagcag gatgtcagga gggagatttc ccttgcagtg
    42061 aaggctgccc tcgaatccga ggtcctcatc cctgaagtgg aggatgcgtc acggatagcc
    42121 cggcagagta cgctcattgc gccttctcac gggactgcct atgattctgt gtccttgtcg
    42181 ccggggactg tctctgaacc gggagttcct gccttcacgg ggcaggtaag gatggaaaaa
    42241 cagtccgagc tgggagtaga ggaagatacg gaggagcgga gccgggaagg gttcctgcct
    42301 gaaatggatg ttctcgggca gctggacgac acctatatcc ttgcatcctt ccggggtggg
    42361 gaagacctga tcctcgttga ccagcatgca gctcacgagc ggatactctt tgaccagctc
    42421 actgcggggg acgcgataca gtcccagtcc caggaactcc tcgtcccggt tatcctcgat
    42481 ctctctcccc gtgaacaatc gatcctgccg gacatcgtcc ctgtcctgtg cgaggccggg
    42541 ttcacgatcg aagagttcgg gggaggatcc tatgctgtcc gtgccatacc tgttgtcctc
    42601 ggcagacagg tggaccccgg tgccgtcagg gagctcctct cggctatcct cgccggaaac
    42661 gagaagcatg gaccttcccg ggcagatgcc atccggaagg tcgttgcatg ccggggtgcg
    42721 atcaaggccg gaacacccct ctcgcgggaa cagtgcagaa ccctcctcaa cgagctgcgc
    42781 cagacctccc acccgttcag ctgtccccac ggcagaccca cgatggtgat tttccggaaa
    42841 agagatctcg acgggctgtt cctgaggagt tgagttacga gggagaaagg atataggtga
    42901 gggggaccga caatagtgtg aacatggtcc gtagtgagcc gccacgccac acggaggaaa
    42961 tcatgccaga cctacaccat acaccttcaa ttgcagcagt ctgcgtgata ctgtgcggac
    43021 tcgtccttgc atcacccgtt gccgcagagt tccttggtgg atctctgata tccagcagta
    43081 ccagtatatc cggcaatgtc gtgatcaacg aaacagtgtc cgtgaaaaag atcacgtata
    43141 cagatgggtt cccgaagatc caggaatgga cattccagga gtcggttgtg aacccgggtg
    43201 cccggacctg gacaacggaa atgacatttg tgccaaagga cacgggtacg aaattttcat
    43261 tttcccggac cgggaacctg ttttccccgt tttcattcag gatctgaagc ggaaggggga
    43321 agtgcctttt ttggcacttt ccttcccgct tcccggggca tgaagaacca accactctct
    43381 tcttttcgca ggggacaggg gtatcccgtg gggattgcaa tctcaatctt gatatagatc
    43441 agcgtggtta tgatcgtttc gggggctttg cagatgattt ctgtcctata cgtggatgac
    43501 gaggaacccc tcctgcacct tggaaagact tttcttgaga ggtattctcc tgacatccgc
    43561 gttgacactg caccatctgc acaaaaggca ttggaaatgc ttctttccgg taaatacgat
    43621 gcaatcgtgt ctgattacca gatgcccgga atggacggga ttgcccttct ccgggaaatc
    43681 cgatcagggg gaagtaacat tccgttcatc gtctttacgg gtaaaggacg cgaggagatt
    43741 gtcatccagg caatcaatta tggtgctgac tattacctcc agaaaggcgg ggacccaaag
    43801 tcacagtttg ccgagctcat ccaccagatc caccaggcag ttgcaaaaag gagggcagag
    43861 gaagaactgc gggagtcgag gaagaggctt gctgacatca tcgatttcct gccggatgcc
    43921 gtttttgcca tcgaccggga agggcgggtc attgcatgga accgtgcaat agaggagatg
    43981 accggtgtca gtgcggatga gatgataggg aaaggagaca gggaatattc gattcccttt
    44041 tacggtgacc gccgtcccat cctgatcgac tacatccttt cgcaggatga gacgataccc
    44101 aaccattatt ccctcatcac ccgggacagg gatgtcctca ttgccgagac agatttacct
    44161 catccacggg gggagcggag gatccttttc gggaaggcga gtcccctcta tgatgagaat
    44221 gggaagatag tgggagctat cgagtcaata cgcgatatca cggattacaa gtggtccgaa
    44281 cgcaggctca ccgaggccct ccggcaggtg tcgggtgcgg aagaaaggat acgggcatcc
    44341 ctttccgaat taaaacaacg cgaggagttg ctcagggaga gtgaaaagaa atacgagaca
    44401 ctctttcacg aggcagctga tatcatcatc cttattgaca cagagggaag gattcttgat
    44461 ttcaacagga aattcatgga agagagccaa agggacccgg aagaagtcac aggaaaggac
    44521 atattctcta ccggtctcat agctccggag taccatgccc tcgttgccgg ttacctggaa
    44581 ggcatcaggg aaggacgaac gatacccata ttcgagatcg aaggcatcca gaagagcgga
    44641 aagaggattc cctacgaggt ccgtgtttca cctctcgttt tggagggcag ggtcacagca
    44701 gtccaggcga tcctccggaa cctgaccgag agaaaagcag cagagaacgc gcttcgcagg
    44761 agcgaagccc tttaccggag cgtggtcgac aacatccagg acgtttttta ccgggcagac
    44821 atggatggga ttctcacgat ggcaagcccc agtttcgcaa ggctgcttgg ttactcctcc
    44881 gtggatgagt gtatcgggaa ggatcttgca cgggatttct atctcgatcc caaagagaga
    44941 gaaaaattcc ttgctgccct tgaagacgca ggagaagtct ttgactacga ggtcacgctg
    45001 aaaaggaagg atgggacccc ggtcatcgtg tcaagtaaca gccattactt ctacgacgag
    45061 cagggaaagc gtgcaggagt cgagggaata ttccgtgata tcacggaaaa taagcgtatt
    45121 atagctgctc tccgcgaatc tgagactttt taccgggcgc tcttcgaaaa tacaggaaca
    45181 gccaccgttg ttatcgagga agatacaacc atcagccggg ttaataccca gttcgagaaa
    45241 ctgacagggt atccgaggga agaggtcgag gggaaaaaga gctggaccga attcgtggtt
    45301 gaagaggacc gcgggtggat gctcgaccag cacaggaaga ggagggttga cccttcaggg
    45361 gcgcccactc attacgagtt cagggtgaag aaccggaacg gagaggtgag gttcgtgttc
    45421 cttaccattg tgataattcc gggaacgaag aagagcattg catcagttct ggatatcacg
    45481 gatgtcagga atgcagaggc agctgtgcgg cgcctcaaca agaacctcaa cctgctttat
    45541 ggcgtaacaa tccatgacat tgcgaacaag gtaacggcgg tccagggcta tcttgaacta
    45601 ttgcaggaaa tgaaccggga cacatcgatc gacgacctga taagaaacgc cctctccgca
    45661 atcgggaata ttgcccgtca catccagttt gccagggttt accaggatct cgggataaaa
    45721 gaaccgctct ggcagaacct cggcgccgtt atttcccggc atgcaccagg ggacgttccg
    45781 gtcagtatct cgtgcagcgg gatagccgtc tatgcagacc agatgcttga gcacgtcttt
    45841 gcaaacctct ttgacaactc tctgcgccat ggggggaatg tcacatcgat atcggttgag
    45901 tgttcaaaaa gcggaaacga cctcgttgtc cggttccggg acaacgggaa gggcatcgcg
    45961 gaggctgaca aagagaaaat attcgagaag ggatatgggg accataccgg ttacgggctt
    46021 ttcctgacga gggagatcct cgcgattaca ggcatttcca tcagggaatg cggagtgccg
    46081 ggtgaagggg ctgtctttga gataatcgtt cccggtggtg catggcggta taacccgtga
    46141 ttgacaggtc acgcatccgg gagatccgcg cactgcctgc agggaaggga aagtacgtcc
    46201 tttactggat gcagtcgtcg gtgcggtccg ggggaaacat ggcactcgcg tacgccctcg
    46261 cgattgcccg cacacgggac ctgccggttg tgacctgttt ttgcatcgac ccttcgtacc
    46321 ccgaggcgaa cctccggcat tttacgttcc tggcagaggg aatactctcg gcaggtaagc
    46381 ggctttcccg gcggaaaata cccctcgtcc tccggagggg ggaccctgtg aaagagatct
    46441 ccgatctcgc gagagatgcg gcacttgtcg tcactgacag ggggtacctc tcttaccaca
    46501 ggaggtgccg cgaggctctt gcccgggaaa ccgggtctcc ttttaccgtg gtcgaggaca
    46561 atgccatcgt cccggtggaa agcgcgtctc aaaaggagga atggtctgca gggaccttcc
    46621 ggagaaaaat tggaggacac gtcccctttt tcttcgacct gcccgcggat gcagtttccg
    46681 tgaggaagcc tcccgatatc gatggtatcc cgtaccggga tgtaaaaaca ctcattcatt
    46741 ccggaatcga cagtaccgtc ggtccatcgc cccttttccg gggtggcgag gacgaagccc
    46801 ggaggagact ggagatattc atcaaggata aacttccgat ttacccatcc cgcaggaacg
    46861 acccctcccg ggacgtgctc tcccatctct ctccctatct ccatttcggg aacatatccc
    46921 ccttagagtg tgcgtccaga gtcttggaga cacaaggaca gggtaccggc gagttcctgg
    46981 accagctcat tgtccgaagg gaacttgcca tcaatttcgt gcattacaac ccccggtatg
    47041 attcgttcca ggggcttccc tcctgggtac ttgagaccct cgcgcatcac gcccgcgacc
    47101 tgcgggaata tacctatact gcccgggagc tcgagcgggc cgcaacgcac gatccctatt
    47161 ggaacgcgtg ccagaacgag cttgtcatta ccggcaagat gcacggctac atgcgcatgt
    47221 actgggcaaa gaagatcctc gaatggacac ggtcaccgga ggaggcattt tctctcgcac
    47281 ttgttctcaa taaccgctac gaactggacg ggagggatcc cagttcatac gcaggaattg
    47341 cctggtgctt tggaaaacac gaccgcccat ggccggaaag acccgttttt ggtaaagtcc
    47401 ggtacatgaa tgcagcaggt ctcgcgagga agttccggat cgatggttac gtgcaacggg
    47461 tggaggccct gatcgaaaag tatggaatac ccggaaggga atgaggcctg cgctctttct
    47521 ccggaagaga ttgcacggtt ccgggaagca gtatacagcc attacagcaa acaccggcgc
    47581 aggtttccgt ggcgggaaac gactgatccg tactgcatcc tcgtctcgga ggtcatgctc
    47641 cagcagacgg gagtcgaacg ggtcatggta cactaccccc cctttacctc gtcatttccc
    47701 ggtttttcac cccttgcaga ggctcccctg gcagatgtcc tgcgtgcatg gaagggtctt
    47761 ggttacaacc ggagagcact gaacctgcat aaaacggcaa ggatcgtcac cagcgagcac
    47821 ggaggcatgc ttcccgcgga ggaaaaagat ctcctctcgc ttcccggcat aggaaaggca
    47881 actgcggcgt caatcagggc atttgcctac aacatgccat cggtctttat agagacgaat
    47941 atccgcaggc tctttcttca ctggttcttc ccctccgggg accgaatccc tgacagcagg
    48001 atcctccccc ttgtccgtgc cactctggac cgggaaaacc caagggactg gtactatgcc
    48061 ctgatggact ttggagcccg cctgcgctcc gttgtcccgg atcccaacca gaggagcgcc
    48121 cattaccaca ggcaggcccc tttccggggg tcagaccgtg agatcagggg acgaatcatc
    48181 tctgtcctcc tccgttcggg ctgcgtggac cagtcggacc ttcctgcaga agtggaggcc
    48241 gaaggtgaca gggttcgtgc aatctgtgac cggatggcag cagaagggct gatcataaag
    48301 gagggcggga ggttcagact tccctgaagg taccctgttg ccgggcaatc cggatcgaac
    48361 cctaacccct caggtaatac ccgatgagga tcaggagcag gccggtgtag aacatgattg
    48421 cccacggcca tgagaatcca aggttgatcg tggaaaaacc tttcaggtcc tggatgagca
    48481 ggaggataaa acccgctcca aaacagagga ggctgatctg tttcttggca cttttttcca
    48541 ttctttcttc tccttttaaa gtgttattgt ctgtttgtat ttattctctt tttcccgatc
    48601 ggagactgaa taccggattt tatcccctgt tctttccttc gggcctgatg atgagggaaa
    48661 agaggtccga ccggggagaa ggggggttgg tccgcgtccc ggactcgata cgttcgccgg
    48721 ggtaaccaag gtcctcgcag aggatgattg caacctctcc cgggatgtcg aggagggttg
    48781 cggcacaaaa accgacgtca aaacccgggt cggcaatcag gaatacggtc tttcccctct
    48841 ccacctcgga gtgcaggtca gcgagggcac gtccgtggtt gcggccatgt gcgaccacga
    48901 ccgagacatc ctgcatcggg atgtggaggc gggcaagtgc gagctggagg gacgagattc
    48961 cgggaatgac ctctcccggc aggtacccga gccccgcgag catcgggtcg ccggtggaaa
    49021 ggacgactgc acccgaagga agatccctta aagagcggta gtcttcgatc tcgtgcacga
    49081 cggcatccgg ccggataaac tcgcgggcaa ggtcgatggc ccttcctgac ccgtatacca
    49141 gccgggcttc cgatagctcc ctgatggcct gtgcagtcag catacccggc ccgcagccaa
    49201 cccctacaat cttcatccgc tgtcccccac gatctcgccg ttacgcgaga ggataacgac
    49261 acgcaggaat gggtacttcg tgcgtgcaat ggcaaaagcc tcttccattt tttcgggaaa
    49321 aacgggtgtc tgcgcaagct cttcaacagt gaggcagcct gtcccttcga gtattcccgg
    49381 gaacaggaac ttcagtacaa ggcccggcag tccggagagg atgatctcgc ccctggccgc
    49441 cccgagtgcc tcccctatcc gcgagccggc gaggactatc tcgtgatcgg gaaaatggag
    49501 gcgggagtag cgtaaaccga ggcggcccgt cgtgatcacc acgcgccctg ctgccgccac
    49561 cctttcctta acagatcctg ccatgtgatc gtcccagggt tcgacgagcc ccgtcgtccc
    49621 aaggacagaa atcccgccga gaatgccaag acgcgggttc agtgttttcg tggcgatatc
    49681 ctttccatcc gggacggtga gcgtgatggc aacccccgga atccctgtca tctccatgcc
    49741 ttcggtgatt gcctccatga tctcctggag tgcaggagga ctgattgccg gctccccgct
    49801 gcgtcccctc ggcgtatcac gggagaaacg gcctattcct tcgcctgttt cgagggtgac
    49861 acccccgtcc cggatctccg cctctgcaac aaagacgagc cctgcagttg catccccggg
    49921 atagtcccct gcaaacttgg aggccccggc ccgtcccccg gaaccctgca cgggcacgtt
    49981 gagggaaatc ccgcagggta tacggaccga aacgctgtcg acggggtatt tcagcgaaag
    50041 aacggctgct ttgcaggcag cagcagcggt tgttcccgtg gtaaaacctc tcctgagcac
    50101 ctttcccgat gcggtcagca cccccagtcc cgaggccgca agggcgagct gttcccggtc
    50161 cctgcatgca gctacccatg cttttgggta cgaaaatcct gtcacagggt cgacgagggg
    50221 ttcactcttc tgcatgtccc cggtccggat ggttctccgc aaacatcgtg atgatctcat
    50281 tgattgcagc gactgcaacc ggtgtgcccc cccgtgtccc gacgtttgtg atggagggga
    50341 ccgggaggga acgaagcctc tcttttgact cggcggcatt gacgaacccg accggggtgc
    50401 cgacgacgag ggcagggcgg cacccttcct cgatcaggtc gcagagggag aggagagcgg
    50461 aaggtgcatt gccgatgaca acgatggcgc catcgatctc gtcccggagc gccagtatcc
    50521 ctgcccttgt ccgggttatc ccctctgcat gcgctttccc ggcatggtca agggcgcaga
    50581 tgaccctgct cccgtgcccc tttttctgga tgcctacctg aaccatgcgg atatcggcga
    50641 tgaggggggc actcctgccg agggcggaaa gcccggcggc gacggggtcg tgtgcaaacc
    50701 ggaggagtcc tgccatggcc aggtccccga ctgcaatcga gcacctctgg cggatgcggt
    50761 cctccggtgt ctcgttcccg atctcccttc gggcaatctt cctgctcttc tccgaaatcc
    50821 tgagtgcctc tccgggaatt gcaccaaggt cagtatacgt attttttctg gtatccccgc
    50881 ggggtgatga ttgtcttgtc attttctccc acttttccta tccttgtctc gactcccccg
    50941 acgataacgg tgctgtgcat gtcgattgcc tcttcgtaat ctgtcacgcc ggcaagtgtg
    51001 gtaacgatga tctcctctcc ttcccggtac gcatttttga caatcccgac aggtgttgca
    51061 ggatccctga accggagggc tatttcgacc gcccgtgcaa agttgtgcgg tctcccgtgg
    51121 ctccgggggt tgtaaaggac cacagggacg cccattgcga aggcacatcg gagcctctcc
    51181 tcgatgatcc cgaggggcgt gaggaggtcg gagaggctca cgactgcaaa gtctccggag
    51241 agcggtgatc caaggaggga ggccgcggcg gttgccgccg tcaccccggg gatgacaacg
    51301 actttcacgg gaggatctga ccgttgtgca acttcgagga cgattcctgc catcccgtag
    51361 acgccgggat ctccaccgct caccattgca acgatgcact tttctgcgag ttccacggcg
    51421 agttttgccc gttcgacctc ctttcccatc gagctcctga tgaccttctt gccctcgagg
    51481 agcggggcga ggggggcaag gtaggactcg ttgccaagga cgtactctgc ctccttcagg
    51541 gctgcaacgg ccctcccggt catctggtcg aggggaccgg ggccgcaccc gaccacgtag
    51601 aggacgcccc gttcttcacc gggcaatggc aacggttaca cctccgaaaa ctgtcttctt
    51661 catgataagt tccttttttt cagatactgc gagggcagca ggttccgcaa caccggcaag
    51721 cccgacggac cctgcccgcg agggggacgc cggcggatac gccgcgagga cagaatcctc
    51781 gaggaaaacg atcgtcccgc ccagcgccct tacaccccct atgatcccct gctcatgtgc
    51841 ctttttcacc gtcgatgcgt agatgcccac gtcttctttt tcaataccgg ccatttcgaa
    51901 ggctttttcg agggcttccc ggacggattc cgccccggtc cctctccggc acccgatccc
    51961 gacggagtac tcgcctttcc ggaagagaat ggcgacacgg ggtcctgcaa tgaccatgga
    52021 aggcccggat accgtgtaga tcgggacttc accgtcgagg attgctgcat tcacagggag
    52081 ggtggattca cggttgagga tgctgcagcc tgcgcgggtg gctgcagcct cgacagactc
    52141 cttccctgac ctgtccgttg ccgttgtgat caccgggaca gcgcccagtc cggccagtct
    52201 cctcgcgagg tcattggccc cgtggtggcc tccgatgagg gggattgcaa acgagaggtc
    52261 aggatccacg acaacgacgg ccgggtcgtg ccacttgtca cggaggagcg gtgcgatggc
    52321 cctcgtcgcg ataccggttg ccatgaccgc aacgatccac ggcgaatccc ggaaagcaga
    52381 tgcaaacgct tcgcgggaaa agacaacgag gttgccgtca aggtattctg caatcctccg
    52441 ggcaggggag aggaaccgtt ccagtgcgat gacagatcct ttcatgaata caggtgcgac
    52501 ctcctgtggc cggaggaggc aggttcgagg acgccgccga tgatgagcag ggccgtcctt
    52561 tctatcccgg cctcccgcgc tttctccgcg atgtctgcga cagttccccg gacgatacgc
    52621 tggtcctccc agcttgcatg gtagacgacc gctgccggtg tatcgggggg acaccggacc
    52681 ctcgaggtta tctcttcgag gtgcgctgtc ccgaggaaaa agaccatcgt ggctctgtgc
    52741 tccgagagtt ccgctatctc gtcatgttcg agggtggagc ctgcaggacg ggtgacgata
    52801 aggctctcgg cgaccccgcc aagggtgagc tgggttttca gggcagctgc tgccgcaaag
    52861 agcgaggaga ctccgggaat gacctcgaaa tcaacgcccg cctctgacag gagctgcatc
    52921 tgctccacga ttgccccata gagggaaggg tcgcccgaat ggagtcgcac aactgttgaa
    52981 cccgcccttg catgtctgac gaggagttgc ccgatatcct cgagccgcat tccgtggctg
    53041 tccactttca ggtgagcggg gcagtcttcc acgagccggg gattgacgag tgaaccggta
    53101 tagacgagga catcagccct cgacaggagg tcgcgtcccc tgaccgtgat aaggccgggg
    53161 tctcccggac cggcaccgac gaagtaaacc cgtgccatct caccgctccg cgtagaggac
    53221 actcaggtaa tcacatgtct cggggaggtc cccgtcacga tacacgtgca tatcagggag
    53281 gtacatcttc tcgacgagga cgaaccgcct gaacccttcc ctgccgaggg cagacgcagc
    53341 ttccctcggt ctccggacct taaggaggac cctgtaccgt tgttccgttc catcagagac
    53401 acagaaccct cctgagagcg atacgccggc caccgctgcg aatgccgtta tggcgctgat
    53461 tcccggttct gtccggcaca ctatcgaagg gtacttttcc tccatgacct ggcagagccg
    53521 cgtgaaagtg gaaaagaagt tcggatcccc gatgagagcg agaacggcag acccggagga
    53581 tgcaaccggg gcaatctttt ccgcgttccg ttccatgcag agtcgaatct gtgcagggtc
    53641 ttccgtcatc gggaagtcaa gtatctcggc atccctgtag ggtgaaacga gtgcgtgggc
    53701 gagcctgccc gggacaaaca cggcatctgc ctcgcgaagg agacggactg cccggagggt
    53761 caggagctcg gggtcccccg gcccgaggcc aaggccaatc agcatggcgg agtccccccg
    53821 acgatgatgg ccaccgggtt agccggcttc cacatgtagc cggttccgat ggggtttgcg
    53881 tgcgagacct ggacgagaac ggcttcccgg aatatcccga gttcgtgcat cagcgggatg
    53941 gcagcagcga cggtatcgat cttcaccgcg ttgacaacga tggaacggac tttcaacccg
    54001 gcaaggaggg gaaggatacg gtccatgtcc ctcgaaccac cgaggaaagc tgcgtcagcc
    54061 cgggggaggc cgggtatgag gtctgctgcg tttccttcca ggaactcgat gttcctcaca
    54121 cctgcacgtt ccgcctctcc cctcgcgaac tcgatcgcct ccctccttgt gtcaattgcg
    54181 tacacgctcg cgacctgccg ggctgcgtgt atcgcgatct tcccggtccc gcagccgata
    54241 tccatgaaac ggtcgcctgg ctgcaggtcg agcttggcga gtgccacagc catcacctcg
    54301 tccttcgtcg gtccgccgga aagacccatc agcaatcacc taccagttgc tcctcgaaaa
    54361 ctattaactc ttgtattttc gaaatagcaa tgaaaaaaag gtcaatggga gagagaagag
    54421 ccttttcctg caggggtgtt gactggaaag ggtatccggt ttcctgtcag ggaaaggcgt
    54481 atcctccgtt cacgggtatt tttgtccggt tcccctccat cccggaacgg attttgcagt
    54541 cataacggga caaggccggg ttcgccctcc ctgtaaagcc tgacgacgtc tccgatgacg
    54601 atgactgccg ggggcctcac ccggcgttcc cgtgcaatcc ctgcaatggt cgcaagggtt
    54661 ccggtggtaa ccctctggtc gggtctcatc cccctttcga tgatggcaac cggtgtgccc
    54721 gggtccttcc cgtgcgagac gaggttttcc gcgatcgcgg gaagattcct gacccccatg
    54781 aggatgacga gggtgcccct gttccctgca aggttctccc agtcaatggc ggatccgtcc
    54841 ttttccgggt cctcgtgacc ggtcaggatc gtcactgacg atgcatattt cctgtgggtc
    54901 acggggatac ccacggcacc agggactgct attgcactgg tgatgccggg gacgagttcg
    54961 acaggaatcc cccgttcccg aaggaccccg agttcctccc cgcccctccc gaacaggaaa
    55021 gggtcacctc ccttgaggcg gacgaccttc tttccttcga gtgcacgtgc gaccatgatc
    55081 tcctcgatct cgtcctgctc gagggtgtgc tgacccccga acttgccaca gtcaatcttt
    55141 tctgcacgtt ccgggagacc ggcaaggatc tccgggcccg ggagctggtc atagaggatg
    55201 acatccgcct cctccagcac ctgttgcgcc cggagcgtga gcaacgcctt tccgcccgga
    55261 cctgaaccaa cgagataaac cttccccttc attccttcaa ccccagtttc gcatatgctt
    55321 ccccgatgag aggcgcggct tttgccttca gttccctggc aaggtcaagg acagaccgct
    55381 cgtctgcaca catgcagtcc ctcctgaccg acctgtcccc cgcaagggac aggacctctg
    55441 catgcatgtg ccccctgtcg cagtatatcc cgaggggggt gaaacatccg ccccctatct
    55501 cctccatggc aaccctctcg aaaccaatgt cacgccgtgt ctgtgggtgg tcgagggcat
    55561 cggcgagcat ttcggccgtc tccccctccc tgctcaccac agcgatcgtc ccctggttgg
    55621 gcgacgggac aaacgtctcg ggcgggagac gggtgccggg aagggtgagt cccagccgct
    55681 ggaggcctgc ctcggcaagg acgatggcat cgaactgccc ctccttcagc ttgcgcaggc
    55741 gggtgtcgac gtttcccctc aggggaacga tctcgaggta cgggtaatgc ttaagaagtt
    55801 gtgcccttcg ccgtgtgctg gaagtcccga cgacgcgaat cttcgggaag gggatggtat
    55861 ggaccaggaa atcggcagga gagtcgcgct ccaggacggc acacgtgacc aggccttgcg
    55921 gcctccttgc cgggatgtcc tttgcgctgt gcacggcagc atcgattccg ccctgcagga
    55981 gtgcatcatc gagtgcccgg acaaagacac cctgtccgcc aatctcgtgg aggggcacac
    56041 cggtcacggt atctccaagg gtcgagatga tcaccttctc tgcctctatt ccgttctttt
    56101 ccaggagagc aatcaccctg tccgcctggg cgagtgcaag ggcgcttccg cgggtgccaa
    56161 tcaggagaga cattgcctgt atgccgtgct gatagtctcc acgtccccgt ccgtgtgtgc
    56221 cacggagagg aagttggtct cgaactggga gggcggcagg aatatcccgg atgcaagcat
    56281 cttctcccag aactgcttaa acgcccccgt atcgcattcc tttgcttccc tgtagttgcg
    56341 cggttcggca ttcctgaaga agaacttgaa catcgaaccc aggcagacaa aggacccccg
    56401 gcctgtatcg gagacagcct cacctattgc ccgcgtcttc tccccgaggt cgcggtaaag
    56461 tgcagggtga tcgtgaatcc attccactgt cgcgatccct gcagcaaggg agaggggatt
    56521 tccggagaac gtccctgcat tgtacaccgg gccagccggt gcaaccatcg ccatgatctc
    56581 cctcctgccc ccgaaggcac cgatgggaag accccctccg atgatcttgc cgagcgtggt
    56641 aatgtccggg acaacgcccc agcgcttctg tgcccccccg ataccaaccc tgtagccgca
    56701 gatgacctcg tcgaagatca ggagcacgtc gttagcccgc gtgatctccc tcacatcccg
    56761 caggtacccg tcctgcggga ggatgggacc gatgtttccc atcaccggtt cgatgatgaa
    56821 cgctgcaacg tctttgtggc gggagagcag gtcttccagc gcatcgggat cgttgtaggg
    56881 aacctggagc gtgtgggagg cgacatcggg caggacacct gccgaatcgg ggatgccaag
    56941 cgtcgttgcg cctgacccgg ccttcacgag gacagaatcg tgtgcaccgt ggaacccccc
    57001 ctcgaccttg acgatatcct ttttccccga aaacccgcgt gcgagccgga ttgcagccat
    57061 cgtggcttcc gatccgctcg agacgaacct gaccatgttc atgccgggat ggtcgcggca
    57121 gagcatttct gcaaatctga cctcgagggg agtgggtgtc ccgtacagcc acccgtcccc
    57181 gacctgcctt cttatggccg cttcgatttg cggatgtgca tggcccagga ggagagggcc
    57241 gtaccccatg cagcagtcga tgagttcgtg gtcatcgact gtaaaaagcc tcgatcccga
    57301 agcccgccgc gtgtagaaag ggtacggggc aatcgcccgg accgggctgc tcacgccccc
    57361 cgggatcagg gtgcgtgcac gtgcgaaata gtcactgctc ttcatcgagc caccctgcca
    57421 cgtcccgtgc aaaatacgtg atgatgaggt ctgcgccggc acgcttgatg caggtcaggg
    57481 tctccagtgc aacctccttc tcgtcgagcc acccccgtgc agcggcagcc ttgatcatgg
    57541 catattcccc gctgacctgg aatgccgcga cgggaatccc gagcgtcctg acctcggcaa
    57601 gaatgtcgag gtaaaaaccg gccggcttga ccatcaggat gtcagcacct tcgtcgaagt
    57661 cgagcatcga ttcgaggaca gcctcgcggg agttcccggg aggtacctgg tacgttgacc
    57721 tgtctccgaa acgaaaaccg ctgtctgctg cgtcccggaa cgggccgtaa agggcacttg
    57781 agaacttggt ggaataggac atgatcgcaa catcgctgtg accctcgcgg tcgagcgctg
    57841 cccggatcga ctgtaccacc ccgtccagca tgcacgaggg agcaacgatg tctgccccgc
    57901 tctgtgcatg cgagagtgcg atcctgtcca tgaggtcaag ggaaggatca ttgaggagat
    57961 cgggaccatg gcgggtgact cccacgatac cgcaatggcc gtgatccgtg tattcgcagg
    58021 cgcacacgtc ggtgatgacg accatttccg ggacttccct cttcactgcc ctgaccgctt
    58081 tctggacgat accgttggga tcgaaggcac acgaggcctg ctcatccttt ttccgcggga
    58141 ttccaaagag gaggagggcc cggattccgg catcccacag gtcacgggca accgttcctg
    58201 cttcggccag gggataccgg acctgccccg gcatcgattc aatggacttt tgtttttgtg
    58261 cagtctcgtc gatgaaaaca ggtgcaacga ggtcgttctt cgagagtgca gtctccgcga
    58321 gaagcggcct gatgaccggt gcacgcagtc ttctcattct tcttttcggg aacatggttt
    58381 ttcacctctg acgatagcag caacgagggc ctctgcccgc tcaaggtcgc cctcctcagc
    58441 acacagcctg acggacatgg tcacgtccga gaggagtttt cgggcaagga cacgcgagag
    58501 gtcgtcaacg atcccgcacg tgcgttcatc gggattgccc aggcgggcga ttgcccggtc
    58561 cctttccctc acccttatag cctcggccca cgtgtggagt gtgccgagca cgtcgtcggc
    58621 ggcatggctg ttgaggagcc ggacgaaccg gaccagttca ccgtcgatga actcccttac
    58681 cctggcagcc tccgccctcc gtgaatccat tgtcctttcg ttgacctcgc ggagatcgtc
    58741 gatggaaaag agtgatacgc cccggatatc cccggcgccc tcttccacgt cccttggctg
    58801 ggcgatatcg atgacgataa gggggcgggg cctggtctcg tggggccagc accgtgcggc
    58861 catgacccgc tcgagctggt cacaatggat aacggggtgg ggcgccgaag tgcacgagat
    58921 gaccacgtcc gagaggatca tgtaacgggg gagatcctcg aacctgatcg ccctgccgcc
    58981 tatcttttcg gcaagggtct ttgctctcga atatgtccgg ttggcaacgt agattgcagt
    59041 gaggttcttt acagccagtg cacgggcgac caggcccccc atctcaccgg aaccgatgac
    59101 gagaatgtgt tttccctcca gtgtccccag cctttcctcg gcaagcctga ctgctgcaga
    59161 gccgacggat actgctcccc tgttgatccg ggttctcctc cgtgcctcga tcccggcatg
    59221 cactgccttg ttgatgcaga gttcaaggat gggacttgtg catccggctt ccatcgcctg
    59281 catgagggca gatttcatct gtcccaggat ctggtcttct ccgacgatca tcgagtcgat
    59341 cccgcaggca agttccagga ggtggcggag tgcatcggtg cccgctaaca gggtatattc
    59401 cttccatccc gcactttcaa ggaatgagga aaggctttcc gggtcgccat ggacgagaac
    59461 ctcgacgcgg ttgcaggtct ggaggaggac aatacccctg aacctctccc tggcctcttt
    59521 caggaactct ttttcgtcgg gaaaccgcat cctttcgaga acgtccgccg tggccgtgtg
    59581 gtggctgatg ccggcaattg caacggggac ctgcagggac gcctcctccg ttgcactcat
    59641 gcaaggtacc tccctgcaat cagggaccat gtatatgtct ctcccttccg gagggcagcc
    59701 cagacatccc tgtctttcag gacgttccag aggatttccc tgcgtacctg cgggtccggc
    59761 tggcactccc ggaggtatgc ccggagtcgc tcctggacac tcaccatcct gtcgaggtac
    59821 gggaacgtct cctcgaggtg ttccctgatg aaccgcggga tggccggact cgctccttct
    59881 gtgctgactg caaggatgaa atgctctccc ctgacgaccg acggtatgag gaagtctccc
    59941 ctctcccctt ccgcgttatt gaagaggatg ccctttctcc tgcatgcctc cccgatcctg
    60001 ttattgagcc cgggatcggg agttgccgca acggcgcaga agaaaccctc aaggagcgac
    60061 aggagttttt cgtccgggat gcccccgaga tcgatcgtga tccgggtgac gggaaggtca
    60121 gtgagagcag gggaaaaaga ccgtgaatag acaacaacgg agccctcctg tgcaaaaaaa
    60181 gcagccttcc gtgcaccaac atcaccgcct ccgaatattg cgaccttctt tttcgaaaag
    60241 tccacgagga gagggatcat cagtataggt gtggagcggg cttttcatta aggtgttggg
    60301 atcgaaggag ccatatccct gatggatgta ccagatccgg gcacgttcaa tgagactgaa
    60361 tccagcgaaa aaagaccgcg agagaccctt ttgtggtctc cctttctctc tctgttcacc
    60421 cgggatcacg gtaaccggag tcggctcggg gacacctccg atgtgctttt ccgcgggttc
    60481 atccaacgcg atagccttaa taggctatac cgcgtagtgt agagagcaat tgcgccgata
    60541 gtgtagtggt tatcactagg cgttgccaac gcctaaaccc gggttcgagt cccggtcggc
    60601 gcactctggt tttgccctct tcccggaaaa atacgagatt ctccggtgca cataccccgc
    60661 ctgactcaaa ccgtcctatt cggaagcggt acctgttcca cgttttcctt ttcctttttt
    60721 cgcaaaacag gggcttttcc ggcacggtac ggtacaggag ctgaccttct cgctgtcccg
    60781 ccgggatgcc cattcgagga ggggtataat tgcctcgcga agccctttgc cttcttccgt
    60841 caggaagtac tccacgcggg gcgggacctc ggcgaacgat tcgcgtccca cgaggttctc
    60901 ttcctggagt tccttcaagg tgtcagaaag ggtctttgga ctgataccgg cgagttcgtc
    60961 catgaggtca ccgaaacgga gccgtccccg cattcccagc ctgttaatga tgagaagagc
    61021 ccatttcttg gatatggtgg aaaagattcc cccaaggccg cagatgcata ttgtgccggt
    61081 atccgtgcac atagtatttt cctataaact tactattttt aatactatta aaaggatagt
    61141 ttcggttgga aaaaaggagg acttttccga tgtgtgaacc gtgctgccac gatattcacc
    61201 atgcaaagcg ggggtgctgc caccccggcg cctctgatgt atgggatgag gtgaagatct
    61261 gtgaggagct caagggtgta tacctcgcca ggatcgaggc tcttgacagg aggattgcat
    61321 ctctcaaaag taaaggaaga gagcaatgaa ccttccggag gatattcgat tttcttcccg
    61381 atgttgaaaa gaacgctctc cggggacact tcaggggatc acctcccccg aacgacgggt
    61441 catccacggg ttcaggctat gggtaatgca gggtgaagga aagtgacaga catcatcagt
    61501 gcacaggacc ttgtcaagac tttcggacgg aacagggcag ttgacggggt ctcttttgct
    61561 gtcggtgaag gagagatatt cgggtttctc ggtccaaacg gtgcaggcaa gacaacgacg
    61621 acacggatgc tcaccggtgt cattcccccg gattcgggga ctgcaacggt cctcggccac
    61681 gatatccgga agaaaccggt gctcgccaag cagggttttg gcgtcgtccc ggagacctcg
    61741 aacgcctaca ccgatctctc ggcctggcag aacatgatgc tgatggggga actgtatgga
    61801 ctcccccgga gacttgcgga aaagagggca tccgatctgc tggtaacggt gggtctcctc
    61861 ggcaacaagg aacagaaagt ccaggcttat tcgaagggca tgaagcagcg gttgatcctc
    61921 gccatggcac tcgtccatga ccccaaagtc ctgttcctgg acgaaccgac cgggggtctc
    61981 gatgtccaga gcacccagat gatactctcc ctgctccggg ataaaaacag ggagggaatg
    62041 accatattcc tgacaacaca caacatggag gaggccaaca ggctctgtca ccgcgttgcc
    62101 attatccggc atggaaaaat tgttgccatc gatgcgcctg agaagctgaa aatggcaatt
    62161 gaccgcgtgc acaggatcga ggtgagcttc gatcgcgggg taccggggga agccctcggg
    62221 gaagtgagtg gtgttatcgc ggtgaaccgg attggtgaca agtaccggct cgatgttctc
    62281 agcagggata ccgcgatacg atcccttgtc gcattcgccg cgtcaaacaa ccttcaaatc
    62341 gtaaccctga acacacttgc acccaccctt gacgatgcat ttctccgcct gacacaggag
    62401 ggcggatcat gaacccggag agtctcccgg aacaggcccg gcgggcctgg gtcgttgcaa
    62461 agaaggatat ccggatctat tacctcaagg gacctgtcct catattcggg gtgttcatgc
    62521 ctgtcttcct cttcctcgcc ttttacatgg gaggcaggga tctcccgctg gcatttctca
    62581 tcccgggact cgtcgggatg acactcttct tttccgcaac agcggtttct ccggccatat
    62641 tcccgtggga ggggtcggca aagacccttg agaggctcgc agcgtgtccc atctccatcg
    62701 aggcaatcgt tcttggggac atgattgcat cagcactctt tggcatcggg attacgctcg
    62761 ttaccgtcct gatcggtgta ggagtcggcc tgccggttct ccacgtggat atcctcttca
    62821 tcgccctttt ccttggtgcc tgctgttttt ctgcactcgg gactctcctt gctgtcccgc
    62881 ccacgaacgt cccctcaaac atcatgatgc tctcgtcact gctcaagttc ccgctcgtct
    62941 tcatatccgg gatttttgtc ccgctcgcgg agatgccgcg gtggggactc ccgcttgcag
    63001 ccatctctcc tctcacctac ttctgcgatc ttgcccggta ttgtttctcg ggtgcccatt
    63061 acttccccat caccctggac atcgggttgc tggccctgtt tgcggtggtt ttgtcgatag
    63121 cgacgatgta cttccacagg aaaacaatgc cccggaggct ctgaaagaaa attgaggtta
    63181 caggcatccg ccgcgggagg ctcatgcaca gtcccagctt ccccgatgcc gaagaaaagc
    63241 cattgggaaa taccggagat actataaggg ggaatgcgtc ttttactatt gttcaaccgg
    63301 cagagcccct gtcgaccccc ccaaaaattg accgaggtgc ttgaaagacg gaaaagagag
    63361 aggaccgcgt tccctgtaac ccctcggaag aggcaggagt aaccgaggag aaaatacgca
    63421 gctggacccg ggcctatgca tcgcgccacg gctggatcct gaatcctgac aagcgtgccc
    63481 tcgatatcgt tatccgtggc cttacaagga actgcaggaa gttcgggcat ccctactgcc
    63541 cgtgcaggtt acgaagcgga aaccccgaaa aagaccagga catcatctgt ccctgcattt
    63601 tccataagga tgaggtccgg gacgaaggga actgtcattg caggctgttt ttccggccgg
    63661 acaaggcaga gtaactgcag cccgggcaaa atgtcacggg gttcttctgc ggatcgtcca
    63721 accacctgat tcctgactgg gtgccggtgc ccctctaata ctcatgagtt tttttttcaa
    63781 ttcaattttt ttgaacaaat ttaatatacg gggatgagtg aatggaacca tgctggactt
    63841 cccgggcagg acccggggag accaccagaa gggggaatga aaaaatgtct gaattataca
    63901 aaaagatggt ccacgaggcc atggcggccc agcgggccga cgttgaaacg gtcagaaaga
    63961 agagaggaca gtcctttgtc atcgacgatg caaaggcata cctcgatgcg gtaaagctga
    64021 tgaaacctat cggggaacag tcaaaagcag tcttctccct tcacgtggaa tcggtcaaag
    64081 cccattttga cgtcctcgag aaactgacac ggactgtccg gcccgaagat gatccattcg
    64141 tcgagcatta ccagacgccc gtggtgatgg aaatcctcta cgaccaggac ccggcgttca
    64201 ggaagagtgc tgatgccttc gtcagggcga ttggaaaggc cgaggccctc ataggaaagg
    64261 aatctgcccg ccggtacgca ggcttttacg ggccgacctg cgttgtcgac tttgctctca
    64321 taccgggcag tacgagcaat gtcgtcaacc agatactgca gaagaccgac atacccgcag
    64381 cccacaagca ggctatcctt gcctccaagt cctgggggat gaacacgtcc tacgggatag
    64441 gagaggtatt tgcccatgag atcgagaagg gtgccaccct tgccgacgcg gtcaaagcag
    64501 agataaagat gctccagtcg gtgtacgacc atcccgtcga gacgcaggtg cgcctgatgg
    64561 acgatgccgg gatgagctcg tttgactgcc ggaagtacat gtccgggtac cggaagaaga
    64621 tggaagcgcc ggtcagggca gcgatcgacg acgggatcca ctacggcaac atcgttacca
    64681 tccctgccta ctgtgtcgga gacatagccc accacatagc ccagtccacc ttcaacatgt
    64741 gcaaggacga cgtgatcatg gccacgatcg atgctgccac cgaggtgatg gacaaaaacc
    64801 tgaatgcagc gatcccgaag tttaaaaacg aatacgatgt cctgtcggtt gcaaccgggg
    64861 catcggcctg cgctgccgag tacctcctcg aactggacgg gttcaacgcc atcatggtcg
    64921 ttgacctcct cacgaagagg tggcacaact acgtccagct gtatccccgg cgcggggcag
    64981 ccgccgagtt gcacaactgt gacttcatgg acatgatcta ccggggctgg aagtacattg
    65041 acaaggcccg gagggcccag aacggaaggc cgggcatgct gaaaccgaaa gtgggaagtt
    65101 tcgagatcga cctctctccc attcacgaga acgaggttct catgaacccg cagaggtatg
    65161 cataccccgc ctgtgccatc accgtgcgtg cgtcggcgat gctgcgcctt gccgactatc
    65221 cctgcctcct gacgagcgag cccgtgacgg ccacactgat gaccaacatc atcgccctgc
    65281 acaaggaagt cgccgcagcc cctgcaagga tctgcaagga ctgtgcatct gccgctctca
    65341 tggacttccg gcactgttac tgccagtgga aggaagcggt ctgaacccgg tggaaggatg
    65401 gtgaagagag atgaagtgtt acgtctgtgc acaggaagga cggtcctcgg atgccgtggc
    65461 ggtctgcatc gtctgcggca tggggctctg cagagagcat gccatgcgcg aggaactgga
    65521 gatgtgggaa gggggctatc ccttccccgc aaagaaggtg aaggcgaaga ttccgcgtat
    65581 cctctgtcct gaatgctacc atgcactcaa ggggaagtga gatggatggg tgaccttgga
    65641 aaacgctgta tcgctgaact tgccggcacc gcgctcctcg tttacttcgg ggcaggtgct
    65701 gctgcgataa cattgatgat agctcgggga accaatacgt caactctttt caatattggg
    65761 ataggcgcat taggaggact cggagattgg tttgctatcg gcatggcatt cgcaatcgtc
    65821 atcgcagcgg tcatctactc gatgggacgg gtttctggtg cccatatcaa cccggcggta
    65881 accatcgcgt tgtgggccac gaagaggttt tccaccggcg agaccggtgc ctacatcgtt
    65941 tcacagctta ttggcgctgc tctcggaagc ctgctcttta ccgccagcgc gggaatggat
    66001 gcggtaacaa tcgggggact cggggcaacg gctccgttcc ccgggatcgg gtacgggcag
    66061 gcgattctcg ccgaagccat cgggaccttc gttcttatgg tggtcatcat gggaattgcg
    66121 gtcgacaaga gggcaccacc cggatttgcg ggactggtca tcgggctgac ggtgggagga
    66181 gtgatcacaa ccatcggcaa tatcaccggc tcatcactga acacggcccg cactttcggt
    66241 ccctacctta tcgattccct catgggggga ccggacctct gggtgtatct tcccatctac
    66301 atcatcggtc ccatcgcagg tgcagtgata gcagcgttct tttacgattt cattacaggg
    66361 gagagcagtg cagctgcctg ataacaggta cagggacagc accgggcggg aaaccatgtg
    66421 agaaaagaag cagccgggcc ccgaatcagg attcgggcag gctgtccggt tctcctcttt
    66481 tcttcgtctc cctggtgaat gctaccgacc ctccggcgtg cattctttat accatgggca
    66541 ggcaagtcct gcatcatgtg ccggaaggtc atgtgtccag cctgcaggga agcaaatgcc
    66601 cgtgtcgcca tgatgagggc atatgtcagg ccgcggggac ccgatggaaa actccggatg
    66661 gtcccggtcg ggtggtggtg cccctcgtgc ggaggattcc ggaaggaatg aaggggagaa
    66721 atccccgctt ttccccgatc cggaacgtat atcacaacgg gcccggaaag actttcttat
    66781 gggccagtgg gtaaaagata cggtcgggct tggtgtattt ctctggataa tcgggtatat
    66841 cgcctcaata ctgctctttt tttcgcccta tgcccccctc atggggtgga tcatcacccc
    66901 tgtatttacc cctgttgcga ttgccatcac gtggtggtgg ttccgcaaac gaaaactccc
    66961 gctttcctat tatatccggg taggactggc ctggacagct attgccattg tattcgacta
    67021 cctcttcatt gtcgtgctct tccatgccac ctattacggc attgatgtcc tcatctatta
    67081 tagcctgacg ttcctgatac cggtcggagt cggcctgttc ctcaatcatc gagagggaaa
    67141 aaagaatgtg gcagggtaaa gggggggatt caggaaccgg aaagactcca tgtatcctcg
    67201 tctcacaata aaaacccgtt ccgggattta ttcccctgtc tgcattgccc gggaaatcgg
    67261 aaatttcttt atcatgtgat tattggatac catctcccgc atatgacctt tttgcaggag
    67321 agcgattccc ctgtcatttc cgccatcttc atatagggta aatgataata tttcaaacgt
    67381 atttgaaatg gacagtttcg tattgtatac ccaaaaaaga ggggcgatgg ttgtccccgt
    67441 tcaatggacg tgggagcccc tccgtcgggg aagaggactc cgtaagtcat gcgagggatt
    67501 gcaatgattg acgctctcat cggatcgctc ctgctgggct gggagacact cgccgggtac
    67561 ctgcaggagc acgtcgtcac atgcctcgtg cctgcgttct tcatcgccgg cgcaattgcc
    67621 accttcatca agaaagaggc aatcctgaag tatttcagcc ctgattcacc gaaatcgatt
    67681 gcctacgggc tggcatcggt ctcggggacg gtgcttgccg tctgctcctg taccattctc
    67741 ccgatgttcg ccgggctctt caagcggggg agcgggatcg ggcctgcaac cacgttcctc
    67801 tacgcagggc cggccatcaa catccttgcg attgtctata cggcaaaggt acttggtttc
    67861 gacctcggga ttgcaagggc tgtctttgcc atcgtgatgt caattatcat cggcctcatc
    67921 atggcgaccc ttttccgatc ctacgatacg gagaccaggg agcggatgaa gcttgccccg
    67981 tcagtccccg ccggagagaa accggagcga cccggatggg ttgtccccct cttcttcgtc
    68041 ctgctcgtcg gtatcctcgt cacggccact gcacaggttg actggatgat caagttcccc
    68101 ctcatctatg ccatgaccct cgtgatcgcc tacctgctga tctacttctt cgagagggac
    68161 gaggtcacgg agtggggata cgagacgtgg gacttgacga agaagatctt ccccatcctc
    68221 ctcgtgggaa cctttgctct cggcatgctc gccttcttcc tcccgcccga gtcgttccgc
    68281 ccgttcttcg ggaacaactc gatcctctcc acgctccttg cagccatcgt ggggacgatc
    68341 ctctacatgc cgaccctcct cgaggtcccg gtaatcggga cgacgtttgg ctacacgagc
    68401 ggggtgatgg ccggcgggcc ggcactctcc ctcctgctct cgggcccgag tgtcagcctc
    68461 ccctcgctcc tcgtgctctc ccgcatcatg gggccgaaaa agacagttac ctacgcagtc
    68521 ctcgtgatca tcatctcggc cgtcgcggga tatatatacg ggctgttcct cgggtaaggt
    68581 gaagacgacc atggtggaaa aggaaaaacc gtgctgtgcg gcagaggccc tccggcgtat
    68641 ccggcaggtg gacgtcgggg gaatcaccgt cgggctcgca atgctcgatg acatcatcga
    68701 cgaggtgcag gagctccacc tgccgacaag ggatgcaatc atcaatgaac tcatcaggcg
    68761 cgtcaaggtc tacaattacg ttcccccgtc ggcagaagag aagtatcgtg aagcaatcta
    68821 cagggagtat gaggagaagg tgaaaccatg aagatcgaga tccttgggac cggatgcatg
    68881 aaatgcagaa ggctgacaaa gaatgttgaa caggctgtcg cggagctggg cgtcagcgcg
    68941 gatatccaga aagtggaaga catcaccgcg atcatggaca ggggggtcat gctcaccccg
    69001 gccctgatag ttgacggtga actgaaagtc tccggccgcg tcgcagacgt cgccgagatc
    69061 aaacggatcc ttaccggagg tgcctgaaat ggcagaaatt ccttcatgta catgtggaca
    69121 gaatgaaaag aagcggatca tctttccctg tgcgggacag gcaaataccg gccagatcac
    69181 gaaccttgca gcgatccagc tgaccgagga aggatacggg agtatcgcct gcgcatcatt
    69241 gcttgcgatc gggtccgagg gtctggtgac cagtgcaagg aatgtcgacg aggtcgtggt
    69301 cctcgatgga tgcccgatgg agtgtgcacg gaagatcgca gaagcccagg gcgttcccat
    69361 cagtcagcac cttgtcatga caggactggg gatcaccaag ggaccctcga ggtcatatac
    69421 tgctgacgac atcgagaagg tcgtctcggc atgctgggca ggagagggta agggtaaggg
    69481 taagggtaag gataccagga cagggtcaaa aaaaggcgca gatccgggca ccggctgtgg
    69541 gtgcggatgc ggcggaacgt gttgaaaaaa gaggagcatg gtcatgcgca ccaggaaaac
    69601 ggaaaattgt tccggcaaca ggtttgggac gagcagcccc cgcgaatgtc cggatgccga
    69661 cctgtgctct gtgcactcat gcggatactc atccacagcc cagtaccctt tgggacaagt
    69721 cctttccggt agaggagccc gatatccact gacccgcaaa aaccccctta ccccggaggc
    69781 atcatgaccg agcgccgcct gagcacgttt gaaaaatacc tcacggtctg ggtggccctc
    69841 tgcatccttg ccgggatcgg cctcggcgcg gttgcacccg gcgtcgccgt ggccctcgat
    69901 tcgttttcag tctaccaggt gtcgataccg attgcaatag ccctcttctt catgatgtac
    69961 cccatcatgg tgaagatcga ctttgccgag gtactcaagg ccgcccgcac cccaaaaccc
    70021 gttgccctca ctttgttcat caactgggcg ataaagccgt tcacgatgta cctcatcgcc
    70081 acgttcttcc ttggttacgt gttcgtctct ttcatccccg gtaccgatgt tctcgcaaac
    70141 gggagcacgg ttgaactctg gaggagttac gtctcgggat gcatcctgct cggcatcgca
    70201 ccctgcactg ccatggtcct gatgtggagt tacctggcac ggggaaacga cggtctcacc
    70261 ctgatcatgg tcgccatcaa ttcgctcacc atgctcgtgc tctacgcacc gctcggtggt
    70321 ttcctcctcg gggtgaacgc aatgccgatt ccgtgggaga ccatcctcct gtcggttgcc
    70381 atttacgtcg ggcttcccct cctcgccggg tactacacga ggaagtggat catccggcac
    70441 aagggaatgg catggttcga gacgaagttc ctccacctcc tcactcccgt ctccatcgtt
    70501 gccctcctcg gtacactcgt actcctcttc actttcaagg gcaacgttat cgttgagaac
    70561 ccgttcacga tactgtggat tgcgatccct ctcttcatcc agaccatgct cattttcacc
    70621 atcgggtact ttgccctcgc ccgctggttg aagcttccct accgtgatgc cgccccggct
    70681 gcgatgatcg gggcatcgaa ccacttcgag gtcgcaattg ccacggcaac catcctcttc
    70741 gggctcgctt cgggggcagc gctcgcaacg gtcgtgggtg tgctcatcga ggtgccggtg
    70801 atgctcatgc tcgtgaagat ctgcctgcgg acccaggggc tgtttaaggg tgaaccggta
    70861 tgaaaatgga ttcaatgctt gtaccacttg agatccacgg cgcgggagcg gtgatggtcc
    70921 cggccgtgga ggagatcgcc cgcctcggcg tgaagcgggt ggagctgctg tatgtgatga
    70981 acatccgcga gacagcgggt gatccgggat tatatgcaca cgaccggcag gtgatgaacg
    71041 actggaaaaa caggatcgaa gcctgcggtg ttcgggacgt gaaggccgaa gtcgtcacgg
    71101 gaattccctg gatcgagatc ctggagcgat cagaagctct ccatccgtcc ctcatcgtga
    71161 tgggctcgca tggcaggtca ctgatccccc gcatgttcct cgggagccag accgagaacg
    71221 tgctccacca tgcacgggtc ccccttcttg ttctccgggt ctcgatcatg aaggaagggg
    71281 atcgggatac ctgcacgctg aacacaggga tctttcgccg ggtcctctac ctcaccgatt
    71341 tttcggccga ggcggagcgt tgcatcccgt ttatcgagtg gatggccgga gcaaaacccg
    71401 accgactggt catcatgcac gtccaggaca cccgccgcct ctggacggcc tcgcaggatc
    71461 agatctcgga attcaaccaa aaagacgcga aaaggctcgc tgacctgaag gccaggtttg
    71521 agaacatggc tattccgcag gtcgtgaccg agctcgtgac cgggaatgcc atcgatgaaa
    71581 tcctggcagt cgaggaaacg ttccatccca cgatgatcgt aatgggagcg aaaggtcgga
    71641 ccggcacggt aagttctctc ctcggaggtg tggcggaagc aatcgtgcac agggcaaagg
    71701 cgcacgtgct ggtggtgaga tagcacggag gatggtgttc tgcccccccg gattacccaa
    71761 ccatagcgca tcttctcggg aaagcgatgt tgccggacct ggcgacgaga agatgtcggc
    71821 gacgatggca accatcgaga ggtggctcgg gaacccggtc acccggttcc tcctccagtg
    71881 gctgtcttca gattgctcac ggtgcgggaa ccggctcgaa gtggccctgt tccggttcac
    71941 ccatggtgga tctgcaccct gcatctcctg ccggatggca tcctggcttg tcggtattac
    72001 cctccggagg agcgggaagg ccttcggagt gcgtgaggat ctgatgaagg aaggcctcct
    72061 tgacccctac ctgaggcggg gcctcaccac agtcatccgg agtattgccc gccatgggat
    72121 cacccgcccg cagcggataa acgcgccatt cctcgtggtc tgggacgtga cacaccggtg
    72181 caacctccgc tgtatccatt gttaccagga cgcctgtcag gcacttcctg atgagctcga
    72241 cacaggggaa gccaaagggg tcatcgacca gctcgcacgg gcaggagtgg ttgcaatctc
    72301 gcattctcgg gcggtgaacc gctcatgcgc cccgatatcc gggagctgat ccgatacgcg
    72361 aaagaaaagg gctttttcgt ctcgcttgcc agcaacggca ccctgatccg tgatgccctg
    72421 gcacaggacc ttgcgtccga tggtcttgac tacatcgaga tctcccttga cggtgcggat
    72481 gctgcccacc atgacctctt caggggaatt cccggcgctt tcgaccggac ggtcacgggt
    72541 atcagggcct gtgtcagcgc cggcctcgac acaggggttg caacgaccgt aacgcgcgag
    72601 actgttgacc atctacctgc catccaccag ctcgctgcca tactgggagc aagcatgcct
    72661 ttggattgtt catgaagcag cataagggcg gggacgaggg ctcttgtgca tcgatgtgat
    72721 ttgtgaccac gaggagagca atcataatga cgagtggcgg gagaagaccc gggtgatgtg
    72781 atgagagcca acggtgtcct tttacggtac gcagtgttta tgcgtgaaca ctttgccatc
    72841 gtcatcatct caactcttct cctcgcgatc gcagtcggcc tggtctcatc ggcaccgggc
    72901 cggtttctcc agcagtacag tgtaattctc atcgtgatca tgattggagc gatgggcttt
    72961 tccatcacat acgagagtct cagcgcctct ctcaaggaat ggtgtgcacg ctgtctctcg
    73021 ctcggcctgg tactgaattt cctctttgca ccgttcctgt gctggctcct tgcactcctg
    73081 ctgctccagg gataccccga ttttgccgtg ggccttgttc ttatcggagc agttccctgt
    73141 gccgggatgg ccatggtctg gacagggctt ctgaaaggtg accttccgct cgcgacggtc
    73201 attaatgccg tgacgatggt gcttgcaccg ttcctcatac cggttatcat gctcctgttt
    73261 gccgggaggt tcgtggtcat tgatacggct gccatgttcg ttcaagtatt cctcaccgtc
    73321 ctcctccccc tcctcatcgg catatccctg cgggagatcc ttgaatggcg atcctgtaca
    73381 ctgaaaggca ggggtgacgc ccagaggccg caggctgtcc gggagaaaga actaaccgtt
    73441 cagcatatcc tccccgtcat gtctgccatc tctgcgacga tggcagtcct gctcatgttc
    73501 atggccatta acacaagcat cccggtcatc gtaaagaatc tttccgccat catcccgctc
    73561 atcgcatcaa ctatcctcat atttcccgtc ttgttcatcg tggcctactt cataagcgag
    73621 cggctctttc cccatgccca gaacatcgcc ctcacctact cagccggcat gaagaacctc
    73681 cccatagcca ttgggattgc aacggtcagc ttcgggggac tcgcgatgtt gccggtggca
    73741 gtgggttttg ccttccagat gctgaccgcg gtagggtttt accaggtcta caggaaatta
    73801 acgtcggccg cctgacaagt gaacagagca tcgtgatggg atgcaccccg ctcatttttt
    73861 cctgcaaagg agcatcaatg cacccatcag ggcaaggatg ccaatgcatg aggaaaatcc
    73921 tggtgcggct gcacgcatgt cttcaccgga atctggaatc tcctgtgcga ggacgagatc
    73981 tccatggaac gagggaaagt gcgactcgac ccagattatg cggtccccat cgatagatac
    74041 atcacacgca atgccgtcca gggatatttt ttccacagcg ccggtctgcg ggtcacagag
    74101 gacgatgctc gatcggggcg aattctccgt gtaaacccat ccaatccgtt ttccatcggt
    74161 aaacggcgag gaaatgtcag gactcctttc ggttcctgcc ggcggctgcg atgaacctaa
    74221 aagggttcca ctcacgggat cgatgcgctc cgttttacct gtggaaatca cgtaaagaaa
    74281 gagttctttg aaagatccct tatcctggcc ttcgaaggtg atacgccgtg tcgtataaac
    74341 caggtaatct cccttcatcg cataatcact gacaccggta ttggacacat ttcccgcgtt
    74401 gttgcggaac acttccgtat ttatgttgtc agtaagagaa tacaggaaaa gaccattcct
    74461 gccgaggtat gcaatcctgt caccattgaa gaggacagcg gcagggttga cgatgggaag
    74521 cgtgcacacc tcttttctct ccccggtgtc aatatcatag aggacgatac gagtgtccaa
    74581 tccttcactc acgtcatttt gccagatgat cttccccctg tcaatccttg gccaccaggc
    74641 gttacctgtg tcatcaatga tcccggcaga tccgttgcga atcgaacaga ggaatacccg
    74701 gttctgtgcg attcctgtcg tgccaggtcc gaaatcgacc tggggggttt caaaccatgt
    74761 tgcatactcc cccgatatct ccggtcccgt gatcgtcatg tttaccgatg gcaacccgac
    74821 ggtctttttc tcaccggtag aaatgcgata gaggtagatt cggttttggg aatcgtcggg
    74881 tccttccacc cttccggtga agaggacaaa gtctccggaa atttttccac cgagggcgtt
    74941 cgttgaatta tcagaaattg ttttcgtcac ccatccggca tctgctggta cggagaccat
    75001 acccagtatt agcgcgacga gcactgccat ggtgcaaaac accgtaaatg accatccatg
    75061 cacagactga tgcctcccat tttgattgat aatttgattg ccatgaaacc acatcaaaga
    75121 gatcccggcc ctccgatgtt gggcccggat actctccatt gaaacctgca ttgtgtaatc
    75181 tgccacggag aaccggcgct gtgcccctcg aaatcgtctt ggtaagattt ttcgtcttct
    75241 aacaacgacg ttgtgaatac tgactgatca ccatgtggca gctggtcggg aaacctcccc
    75301 tacgtcgtca cacaggtcag ggggaaaacc gtgccgaccg gcaggcagtc ctcctgattg
    75361 ccatactcac ctcgtttctc acgccgttca tgatctcatc ggtcaatatt gccattcctg
    75421 cgatcgggtc agagtttgga gcagatgccg tcctcctcgg ctggataccg acatcctaca
    75481 tcctcgcatc agcgatcttt ctcatccctg tgggacggct ggctgatatc catggcatgc
    75541 ggcgggtctt ctttccggga attgttattt tcaccgtggc gaccgtcttc tgtgcgtttt
    75601 ccgtctcaac tccgatgctc atcggccttc gggtgatcca ggggatcgga aatgccatgg
    75661 tcttttcgac tgcagttgcg gcactcacgg cagtctatcc cccgggaaag aggggaatgg
    75721 tgctcgggct cagcgttgca gcctcctaca tcgggctttc cctcgggccg gtgcttgggg
    75781 gtgtactgac cctgaacctc gggtggcgga gcatttttct cgctgcggtc cccctggcag
    75841 tcatcattat catgctgctc gtcaggaacg gccatgaatg gaccgggacg tgccaggaaa
    75901 aattcgatct cgcgggttcg gtcctctacg gtttcatgct cctctgcctc atgtacgggc
    75961 tctccctgct tcccgggaca gaaggatggg ctctcgtcct tttcagcatg ccccttttcg
    76021 cagctcttat tttctgggaa cttcgcacgg atagcccggt catcgaaatc gacatcttcc
    76081 tgaaaaaccg tgttttttct ttctcgagca tcgcgaccat gatcaattac tgtgccacgt
    76141 ttgcgatcag tttcctcctc gccctctatc tccagttcaa cagggggttc gatccccaga
    76201 ctgcgggttt tatcctcgca gcccagccgg tcgtgcaggc gatcttctct ccggcagccg
    76261 gccggctctc tgaccgcgtc gaacccggag ttattgcatc ggccgggatg ggtgcaaccg
    76321 cagtcgggct tgcgatgctt gccttcctta cggaggagac gcccctcttc ttcctcgttg
    76381 cagctctcat catcctcggc ctcggttttg ccctcttctc ctcgccaaac accaatgcca
    76441 tcatgagttc cgtcggcagg gagttcctgg gtgtcgcctc cgccactgtt gcgacagccc
    76501 gccaggtcgg catgatgctc tcccttggta taaccatggt cattttctcg ctgatcatcg
    76561 ggcgtgtcca gattaccccg gacgtgcata cccccctcct ggcaagcata cgcatcgcgt
    76621 ttaccctgtt tgccatcctc tgcacggtcg gaatctactt ctctctctca cgggggaagg
    76681 tcagggagaa tgctttggtc acgtgattct ggcagggatg aaccgtttgg tctgaatttg
    76741 cgagggagat tgaggaaggg ctactggttt tcaggctccc tccacctttg atggtatctc
    76801 actgccccgg gatgatactt caaaggcgat ttggtgatga ggttggaaaa aagaggcaat
    76861 tggattctga tcctccctac acaaaagggg aataatggat atgaatccca cgtattctac
    76921 ccgatccgca ccagcctgtc gaggaagacc cctgcccaga ggtacccgat gaaaccgccg
    76981 ataatattcc ccacgacgat cccggaatag acaccaaact cgccaagccc gagcaccatg
    77041 ccaaggatga atgcaaagac gatatcgaag gcaagggccc ggagaaggct gatgacgagg
    77101 gatgtaaagc catgccctgt tccctggaag acagaggagg agaacattcc caggggtatg
    77161 aaggggtaaa agaagcacat ggtctggaag aagaggatga aggccgggga gaggtgagcg
    77221 ctcccgggtg aatacgtgaa gagtgccgtg atctgggggg agagcaggta ggtgaggata
    77281 ccggtcacga gaccgatgac aaccccgatg cgtatcgagt accggtgcac gatccggatc
    77341 ttctcatact ccctcgcccc gtatgctgct cctgaaacgg caatgaccga tgttgcaatc
    77401 cctatcaggg ggacgattgc aaacattacg attctccagc cagaggtata gacagcaaca
    77461 gcatcggtgc cggcgatcgt gacgaggatg aggttaatcg aaagggacat gaccgagagg
    77521 aggagatact cgaggctggc cgggattccc acaccgagga tggaccggac aatccgcatg
    77581 tcaggcggga aacccctgat tttcaggttc acaaaggtat cctttttgac aaggaaccag
    77641 tatgcgagca cgacgagaac tgatgctatc gagatgacgg ttgcaatcgc tgcaccggct
    77701 accccgagtc ctgccccgta gatgaggatc gggtcgagga tgatgttgag aaccgacgag
    77761 acggccattg catacatcgt tctctttgtg tccccttcag cccggagaac ggcataggcc
    77821 atctggacga cgaggaaaaa taccgtcccc aggaagacta tctgcccgta ctccactgcg
    77881 atatcggtca ccggccctgc accgagcagc accacgatgg ggcggaggaa gaggacaaat
    77941 acgatcatca ggaacgcgga aacgatgaaa gcggtgagga tggcgtggct tgctgcagta
    78001 tccgcccctt ctttgtcacg cgccccgatg catcgggcga caacggaggt tgccccggca
    78061 cctaacccgt tggagagagc catcaggatc atgaaaagcg gagtgacaaa accgacaccg
    78121 gcaagggcat cggaactgat accggagacc cagattgcgt ctgcaaggtt gtatatcgca
    78181 attaggagca tggcaacgat catcggtccg gcaagtttcc tgacggcaac ctccgggtcc
    78241 ccgcggagga tgctgactcc cttcgtgagc tgttcgtcga aggcacgatc aggtgttacc
    78301 ccgcttttat ccgatgtatc agtcatctcc gcaactctct cctatcaggt gcatgctctg
    78361 tcgcgcaagg acccccagaa ggtcccggac catgtcacgt tcctcccctg caaggacaga
    78421 aaggagttcc ccctcccatt ctgcctcgat gccgaggatc tcggcgattg tctccctccc
    78481 cttttccgtc agaaacagcc cccaggcacg tcttttcccg ggtatttttt tccgggagat
    78541 gaaaccgctc cgttccagcc gccggacggc acgggcaacc gttgccttgt cgaggtagaa
    78601 gaaccgcgca agggtctcct gcatcacgcc ctctttccgg gacaggtaca tcaggatggg
    78661 gaactgcccg gcggcaaggc cccttggcac aaggtgcctg ttcagggcga tggagtggtt
    78721 ccggtgaatg agggagaaaa aggctcccag gggaagatca ggatgcatcg ggaatcaata
    78781 gcagtagagg tgagcagggt tccggcataa aagttgcgta tgcaacaata aaaattttca
    78841 aaatttcatt tcatctgaac gagggaaaac ggaaggcttt ctgcatgccg ctcttgaaaa
    78901 ggggattggg gctttttgtc tcaggatacc tgcatgaaga tatcaggaaa ctcctctgac
    78961 ttctcgagcg atctcacccg tgttttcagg atcagtgtgt gaccgatgca cctggttgca
    79021 agaaaaccgc agtcagcgtt gatctgaatc gtttccattc gcaaagaccc acccggaagg
    79081 tcaccgatgc acctctcgat ggatggtgcc ccgttgatga atatcctctc tcctgcatcg
    79141 ttgaagactt ccaggacgac acagacagaa tgagccgtct cgtcacccgt gtttgctatt
    79201 gttgctgttg tctcccggca ggtaaggccg caaaccgagg gagcaccgga gtccagggtg
    79261 aatgcaacgg ggcgggggcc gggagtcgga gtgacggtta ccgggattgt ctccctggtt
    79321 tgaacaagcg tcatctcggc caaccgatcg cctgccggtg ttgctgccgg agtcccgtta
    79381 cccgtgatgt cccgtgtcgc acccggatct ggtgtgaccc tttcgccctc ctgaatctgg
    79441 tcacagaaca aaagacacat gccaagaagg atgcatatcg cgatagcaag gatcactgcc
    79501 agtattacat gggttttttt catccggtct ggtatatgac aagaaaggac aagaacccac
    79561 ccatcgtacc ctgcaggaga gtaatcctat atggggaaac cagatacaat agggagtaga
    79621 ggaaagtatc tccctgaaat gattttctgg gttatttcaa aaggagcacg ggataatggc
    79681 tgcagtaatc gagacaaaag ggctttcaaa ggtctacggg gacgtcacgg cccttgactc
    79741 cgtctccctc tcggtggaaa aggggacgct ttttggcctc ctcggtccga acgggtccgg
    79801 caagacgacc atgataaagg tgctgaccgg ccagatccgg ccgaccgggg gttttgccac
    79861 ggtgcttggt cttgatgcgg agaaggaagg catcagggtg agggaaaaag tcggtatcat
    79921 tcccgaacag gaatctccgc ccagtttcct gacggcgatg gaatacctgg agtttgtcgg
    79981 ggctgtcagg aagatccccg acatcgggga acgggcagaa aaatggttcg agctcctcga
    80041 gttcggtgat aaaaaggatg tactgtgcaa ggatctctcg aggggtaccc gccagaaact
    80101 catgtttgcc caggcattca tccatgaacc tgtcctcgcc ctgatcgacg agccgctcat
    80161 caacctcgat cccgtcatgc aggacgtggt caaggaattc ctctccgact acgtcaggaa
    80221 gggtaacaca atctttgtct cgacgcacat cctcgaagtc gctgaagaga tctgttccag
    80281 gtttgcaatc ctccacaagg gaaaactcct ccacgcggga tcagttgcag atgtgaccgc
    80341 ggatggcggg catctccccg ggttcttcct ctcgctcgtc cggaagggtg gccatgcctg
    80401 acctcttttc ctgcctcatg aaagaggagt ggaggatgca ctccacgatg ttcgggagca
    80461 tttcctttgc gctctttccg gtaatgatct ttggaatcgt gttcatgggc tcgttcctgc
    80521 tccctctgct ctctgtcgcg ttccctgcag gtgaccttgc gtttcttgcc catgcctcct
    80581 tccttctcct cgggttcatg gtcggtggct tcgggctcct cgggaacgag atgatgaaca
    80641 ggaggtttgg ccaggcaagt ctcctcgtgt attcaagccg gagcctgccc ctttcagagc
    80701 ggttcatctt tacaaatttc gtcgtaaagg acatcgtata ctatttcttc ctctgggttc
    80761 ttcccttcgg gggcgggtac atcgccgcat cgcctttttt gggggttccc ctctcacggg
    80821 cactcctcct cctcctgacc ctttcccttt catttctcct cgggctctgc gtggttttcc
    80881 tcctctcgtc cctctatgtc aggtcaaagg cagcctgtct cctcatcgtg atctttctgg
    80941 gtattgcagg cggggtgtac acgatctggt cgggcacaaa cccgaccctg ctcttccccc
    81001 cgtatctcct ctactcggcc ttctcgtgga tgacgtttct tgggacgtcc attgcggttg
    81061 tcacgatgtt cctcgcatcg gtcgtcctct tttcgccgga aggcacgggt ttatcgcgga
    81121 cgtacaggcg caggctcggg cgccttgcac gggtgctgtc gttccttccc gaatccccca
    81181 ttgtcgcgaa ggatttcctc gatctctccc ggagcggcat cggcatcggc caggccctct
    81241 tctctttcgt actccctctc gtcgtgatct ggttcttcct ctcgcttctc cggagttcct
    81301 ttccccctaa cgggttggtc gtcatcttca gccttaccgc gggcatcatt gcctcgacca
    81361 tctacacgtg ggtgacggaa ttcgattcgt tcgggcccta ctcctgcctc cccgttgctg
    81421 taagcaccct gattgccggc aagatgacaa cgtttttgtt cctgcaggtt ctccccgcgg
    81481 tattcatcgg gacggtggca ggcatttctg ccggtccgga gatgattgcc ccggccatcg
    81541 tcctgtgcct ctcgatttcc atctatgccg ccgccgtgat ggcgttcctg tgtggtcttt
    81601 ccccgagcgt ccttgtgtat gacgtgcgtg tcctcctcac gtacctggtc cttgacgggg
    81661 tggcactcgt cctctttgct gcggtctcct ttgccagctc cctgtacgcc ttcctctcag
    81721 tctttctcct gtttcccgca tacctccttt tcagggcagc aggggcccgg tgggatgcac
    81781 gggaccctgc cggcatatga atggttttgt cacctctttt ttggcgtgga tgaacgagtg
    81841 accctttttt ttggaggatt ctaaaactgg atgacatgtt ttcctgtgcc agttgcattt
    81901 catatttttt ttgaataatt ttattaggac gatagtccta caggtggctt ggtggtacca
    81961 tggatgccta tgcaggaaag atagccgata tcgatctgac caggaaaaaa gtgacaatta
    82021 ccgcgacgcc ctctgactgg aagaagcggt atcttggagg gaggggattt ggcgcccgtg
    82081 tcgtgactga ccgggtcaac ccccgcgacg acccgctggg ggagaaaaat gtattcgtgc
    82141 tcgcgtcggg tcccacgacg ggaacaggga tcccgctggg atcgcggtac gagataagcg
    82201 cgaaatctcc cctgaacggc accctgatgt cctcgaactc cgggggagtc ttcgggtgga
    82261 agctcaagag ggcagggttt gacgcggtca tcctgaacgg gaaggcagaa aagccctctt
    82321 acatctactt aaacgaagga aaggccgaga tccgggacgc atccccgtac tggggaaaga
    82381 cgacccacga ggcgaccgaa atgatcctct cggacctcgg ggacacgaag gcaaaggttg
    82441 cctgcatcgg tcccgcggga gagagaaaga gcctccttgc ctgcgtgatc aacgacatgg
    82501 acagggctgc cggccggtcc ggtggcgggg ccgtcatggg atcaaagaac gtcaaggcca
    82561 tcgttgcagc tggcgacctt tccatcggga tagccgacga ggagcgcctc aacacagtca
    82621 aggaacgcgt cagggagaaa ctcgagaaaa acggcatctg ccaggcactg acaaagtacg
    82681 ggacggccgt cctcgtcaat atcatcaacg aagccggaat cctcccgacg cgcaacttcc
    82741 agtcggcaca cttcgcggac gccgagaagg tttctggaga ggctctcgcc gagaagtact
    82801 taaagaagaa caagggatgc tatgcctgca tcgtccggtg cagcagggtg acagaggtcg
    82861 atggagagat ccacgaggga ccggagtacg aaccgctctg ggcattcact gccgacctgg
    82921 gtataaatga cctcgcattt gccacaaaag ccacgtggct ctgcaacaag ctggggcttg
    82981 atgcaatcgg cactccgacc gcgattgcat gtgcaatgga gatgaaggag aagggataca
    83041 tcagggacgg cccgcaattt ggctctgcgg aggggatcct cgatcttatc cgccagatgg
    83101 cataccggga ggggttcggt gctgaactct ccgacgggtc ctacaggttt gccgaaaagc
    83161 acggtcaccc cgagctctcg atgagcgtga aaaagcagga catcccggca tacgacccgc
    83221 gcgggctcca gggtcacggc cttgaatacg cgacatcggt ccggggtgca gaccatgtct
    83281 acggttacat ggtctcgcct gaagtgctcg gtgctcctgt caaactcgat ccctacacga
    83341 gcgagggcaa ggcgcagtgg acaaagacct tccaggacct cacggcggca atcgatgcat
    83401 cgggtatgtg cctcttctcc tcgtttgccc tcgacgccga tgactatgca gacctgatct
    83461 ctgcagcaac ggggatgtcc ctgacaggca agggactgct ccacatcggg gagaggatct
    83521 ggaacctcca gaggctctat aacctgaagg cggggtatac caaggacgac gacacactcc
    83581 ccccacgcct cctgaacgaa ccgctccgcg agggtgcccc caagggaagg gtgtggcagc
    83641 gccagcccct tcttgacgag tactacgaac tccggggatg gga
//
LOCUS       DAOOJU010000005        70817 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_431_length_70817_cov_16.298169, whole genome shotgun sequence.
ACCESSION   DAOOJU010000005 DAOOJU010000000
VERSION     DAOOJU010000005.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 70817)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 70817)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70817
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_431_length_70817_cov_16.298169"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1471
                     /locus_tag="PK679_02415"
     CDS             <1..1471
                     /locus_tag="PK679_02415"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HPC54843.1"
                     /translation="QYRNFCSPMPPTALHRGTDARKLPTGTNPMVIRVITMAAVAMAV
                     IDGIVVSIALPTITRAFSADIAQSQWILTGYLVTETSLLLIFGRVSEFIGKKRLFLAG
                     LILFTTSSIACGLSSSLWDLVIFRALQAAGSAMIFSICAAILYETSGPGEQGRVMGYI
                     GTTTAAAAVAAPLLGGIITGSLGWEYIFFINGPIGLTGIALFLLLSPPESASANTFSM
                     DWPGAASLVSFLVFLVLSLAEVSPGHFHAPGVVFFLFLSVLSLFLFIMAERKSPCPLL
                     DLTLFRDPRFLLPNMSMACVYIAFFMLYLVGPFYLEGALGMDPLGVGFVFLVIPVIII
                     VGSPAAGLLYDRRNARTLPAWGIGIAGASLFLLSFAVLVREIALIIALFVPLSLGISL
                     FLAPNATEIMRSLPLERVSLASSMSATLKNLGMIAGISLSALFLSLELSAYGYSLSFQ
                     DADPVILSFSIQKILVTGSIFCAIGAILSLVSTRSPGER"
     gene            complement(1741..2148)
                     /locus_tag="PK679_02420"
     CDS             complement(1741..2148)
                     /locus_tag="PK679_02420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54844.1"
                     /translation="MLNIEGLSSEAKVGKILILVSLVIGILVLLLLAVVGVAVYTAGV
                     FSTLGVSLTIPLVIVAALAAVRIAGLVMGFLALFSTEKKDFSRAGIYAIIASVLPPLD
                     IIMLIGGIFCLVSREANAGKTDETRKDPDLPGL"
     gene            complement(2241..2837)
                     /locus_tag="PK679_02425"
     CDS             complement(2241..2837)
                     /locus_tag="PK679_02425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2115 domain-containing protein"
                     /protein_id="HPC54845.1"
                     /translation="MHQKDTPIYEEICRSCRRISAAQTRGEAGTLMAQEISTFSLFDL
                     QVIMGRVRYEVHRLPPRYRKVAAPYLLGQIVDAHHELLLMCARGEFSRMVQPIREKDV
                     YDSYFSMVPDGCFVFESHREYLPQFHSPRHRLFYYILAGFAMFVLERPGHPVGTPFPG
                     GLSVRENNGKFYCPIRDKEKDVFFALCNFCPAVQDEES"
     gene            complement(2846..3736)
                     /locus_tag="PK679_02430"
     CDS             complement(2846..3736)
                     /locus_tag="PK679_02430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54846.1"
                     /translation="MVKNEHYLVTLSLVLVSLCFVAHASALVQETTYLGRVTAMDPLS
                     LTLTIRAESQYGCSYSGGTPTCSFSSIAPLQVVGTVPDEGAFNTFHNGDLVAATILGG
                     TGGRWAALALVVVPPGSGTYLVSDIYGDPRTIPLDLGADYQFAYSTLPDCSTCSGSVC
                     KALSARVVIKSGDTVLLEQSLNNGESARYSGRNDGSWISVLYLSGEAAPDTCAGATPA
                     TGIQPVSSFVIHVNPPVGGFTAPTGIKSPAETQENKEKPLQAQGPEPTRAAGFLLTPL
                     AAMGGMALLYRVRRKNTRNT"
     gene            complement(3884..4303)
                     /locus_tag="PK679_02435"
     CDS             complement(3884..4303)
                     /locus_tag="PK679_02435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible PsiE family
                     protein"
                     /protein_id="HPC54847.1"
                     /translation="MFDNLVRFEKGIYYILVVLLAFVILFSVAELVFEIFRGIVLDTT
                     YRLDNHEILSIFGFFLLVLIGIELLDTIKAYIRKQEIHVEIIVLLAIIAVARKIILLD
                     PYGEVPLSDLTLWGMGVVVICLAGAYYLLKKAGISVG"
     gene            4496..5785
                     /locus_tag="PK679_02440"
     CDS             4496..5785
                     /locus_tag="PK679_02440"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC54848.1"
                     /translation="MQVWSALLGGVFIAAFIVGIAASSPQPGDQPGYLRIESRPPGAM
                     VIYDGMLIGMTPITYPVYPSDSGPHTIVVSATGYHSYTTSYVPKVSAGKTDYISAELT
                     PTGSLGTLVVKSRPTGALVMVDMGKGQQAPWTYQDIRAGGHLVQAYLSGYQPFATIVD
                     IPDGGTITVDALLQPLSETGIIQARSSPGGADVYVDGIYRGSTATTIGNVAAGTHFVL
                     LKAVGYQDWTGLVEVRTNQITPLDITLTRYTAPESGFIYVNSDPAGASVYLDGVFQGI
                     TQAGNPLDMTGILPGEHTLTLTLDNHEEYITRVMVKAGETTQVNAVLTPSQSIAASGI
                     LQVISDPGGANVFIDDTCRGITPLTLSSVPAGSHTLRLTLPGYRDHTLTYNQTPGGTS
                     HIEVVLTPELPKVALPGLLPLIALLSLGFYATWRKGY"
     gene            complement(5840..6238)
                     /locus_tag="PK679_02445"
     CDS             complement(5840..6238)
                     /locus_tag="PK679_02445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein MoaE"
                     /protein_id="HPC54849.1"
                     /translation="MIKVTRDDFDPGEIIEGARQRNVGAVVSFLGIVRDDGIERMDVE
                     AFEEVAEQDLQAIAREAEAKFGVVHVDIIHRVGHLSVGDSIVLIVVGASHRKAGFLAC
                     EYIIDRIKEHVPVWKKEYTREGARWVEGGH"
     gene            complement(6257..6541)
                     /locus_tag="PK679_02450"
     CDS             complement(6257..6541)
                     /locus_tag="PK679_02450"
                     /inference="COORDINATES: protein motif:HMM:TIGR01687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HPC54850.1"
                     /translation="MVDTVHVRAFARFRELFGDALEVRVKVPATVRSVVQEIARMNPD
                     GAHEILDGEGNLRKSVIVLVNRERIPGNGREDYPVHPGDEIALYPPVAGG"
     gene            complement(6534..7292)
                     /locus_tag="PK679_02455"
     CDS             complement(6534..7292)
                     /locus_tag="PK679_02455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="HPC54851.1"
                     /translation="MQRRQKGLSDRDRERYLRQLPLVGEEGQKRLLDASVCIVGAGGL
                     GCPVSLYLAAAGTGYIRIVDCDIVSRSNLNRQVLYGEGDIGKSKAGVAAEKVGTLNPD
                     IVIEPMEVSLSGDNGSTVADGVDIIVDALDNYPARYLLNKIALEKDIPLVHAAVTGYF
                     GQLLTVLPGRSACLRCAVPHPPEITTSPPVIGVTAGIMGCMQAGETLRILLGDEPIAR
                     DALMVWDGKAGCWEKICISRDPECPGCGSWRNNG"
     gene            7469..8293
                     /gene="larE"
                     /locus_tag="PK679_02460"
     CDS             7469..8293
                     /gene="larE"
                     /locus_tag="PK679_02460"
                     /inference="COORDINATES: protein motif:HMM:TIGR00268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HPC54852.1"
                     /translation="MAEKGCRNNSILLERLKDRLRVYDRLLISYSGGVDSSFLTFVAK
                     DCVPGGVVCVLLDSPLIPRWIVKEAKERASQWNVPLEIVSFPILEESAFCINGKDRCY
                     ICKKKGAGILRDIACRMGIKTIADGVNSTDLREFRPGVRAMDEAGIVHPLAACGFEKD
                     DIRVLSRMLGLPFFHQPSFPCLATRIPYGTGIARDVLQVIEQAETFLQSLGLSVLRVR
                     LHGACARIEVPPRDMHLVLQSGNEISKKFRELGIPHASLDLVGYRSGSMDENGHKH"
     gene            8405..9166
                     /locus_tag="PK679_02465"
     CDS             8405..9166
                     /locus_tag="PK679_02465"
                     /inference="COORDINATES: protein motif:HMM:NF024299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC54853.1"
                     /translation="MENKVSPTIDPGLSKAAWLSCLGRYHEAIRIFSSPLPGVIPTAE
                     YHAAWAFSLNREGLFDEALKHCGEALNLDIRCIDAWFVRGLTLSYLARFREAVECLEK
                     VVATDPGHAEAWYIRGNCLYSQGDYTGAVESYDRVLAIEPRYPKALYNRGVALADMGD
                     YESALASYDACIAINPGVGVVHTNRGVALAGLQRYEEALDAFDLALSLNPEDVSALNN
                     KAICLSRLGRDNEAMDVMEQARKLSRLPHVRRGVL"
     gene            9263..10438
                     /locus_tag="PK679_02470"
     CDS             9263..10438
                     /locus_tag="PK679_02470"
                     /inference="COORDINATES: protein motif:HMM:NF012375.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase component 1"
                     /protein_id="HPC54854.1"
                     /translation="MNVLPASLEIPRVTCALFGAIKAVATLKRTVVLVHGPRGCVYHI
                     NYILGMRGDRHNPVFSTCMDEHDVVFGAEDRLRNAIEELDRLKRPDMIVVLSCCASGI
                     IGEDLESACRAARTDALVIPIEAGGFSGDFSTGYATTLRALVARTAKRGVEKERGTVN
                     LVGMLRGGPDLREMKHLLSLIGISVGTVIPAGATVADLQNAGRAERNIVICETSGLEA
                     AKFLEETFGTPWITVPFPVGAELSLEFLRDVSVSLGLPVPDSRIIAREHFSFSGRKPA
                     IALFAGPTRAIALARFLRSHGLSPRTIILDFPSPLLERIREAAGPECKILVAPGWETI
                     EETLVSLDIDLIIGGLMERSLATRLGISLIDVMHGSQKTAGAGGGDNILSLIGKCKK"
     gene            complement(10514..11146)
                     /locus_tag="PK679_02475"
     CDS             complement(10514..11146)
                     /locus_tag="PK679_02475"
                     /inference="COORDINATES: protein motif:HMM:NF024816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC54855.1"
                     /translation="MEEKDWIEKAQRAKNMGKLEEALAAYREALACNPRNRSAMEEMG
                     DIYYELGRHAEALSMYDAALAEDPHNLLVLYKKGYTLRKIHRCEEALKSLDVALSLNP
                     DFLYALNDKGYCLNELGRYSEAITCFDHSLSISPRNIRVLASKGIALREIGRLEESLE
                     CFDRALELNAVNAFVYYQKSLTLRAMGRIKEADECIARINFPMPGKGIHK"
     gene            complement(11338..11832)
                     /locus_tag="PK679_02480"
     CDS             complement(11338..11832)
                     /locus_tag="PK679_02480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54856.1"
                     /translation="MAGPVARKDESLVRDELRQYLQEIDVTILREFDEGEFNGFWVRF
                     GDFPILLENQKKKSYYIVAFQITLPAGPEVDALNSYYEKKDAQFIYELTRAFTSPLTG
                     FSRIIEGGRVIGFTISRYIYPFYHDFSVKDLDRAIQAVVSQGAIGIAFLKTILPEGKE
                     IPAE"
     gene            11835..12482
                     /locus_tag="PK679_02485"
     CDS             11835..12482
                     /locus_tag="PK679_02485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54857.1"
                     /translation="MSSYDLNCCNPFAAGAVYRWYRLMYMTSRFNDYLYPMSVSVRGG
                     DRISRDTVRRPGFGMCPTDVGHVKGTDPEQADVGGEKIVDERFWKLLLPGIVLAGMIL
                     MTSAGADQNQNMGENLMSSSYHVFPVSPDIPTTSGIDTPLSTEWESYTPPGTTDLTPY
                     ESLSTRSARGTVSAWAKQGSSGGSTGGRVTIIEFKQMVTASGNIQKFMFSASAVL"
     gene            complement(12530..13651)
                     /gene="dinB"
                     /locus_tag="PK679_02490"
     CDS             complement(12530..13651)
                     /gene="dinB"
                     /locus_tag="PK679_02490"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HPC54858.1"
                     /translation="MILDHDGPGPMPGRKASPRIIIHVDMDSFYASVEVRHYPDLAGK
                     PVIIGPDPAVSGGRGVVLTCSYEARKFGVRSAMPVTRAHTLCPHAIFLPPRHDLYQET
                     SERVMDILEGYADRFQQVSIDEAFLDVSSCGDYAAATELAKRIKEDIYRAERLTCSIG
                     IAPGKSIAKIASDLEKPGGLVVITPGKIREFLSPLPVGKIPGIGPKTAAALVNLDIRT
                     IGDLAEADIQDLRELFGKSAVTVRDIARGIDDDEVRESRRIQSISREQTFSPDCGDPE
                     EVTRILLELSDELCRELESEDAYARTITVKVRYPDFTTLTRAQTLPRPTREVRHIRRA
                     VIGLGLPLLHDQKVRLAGVRLSSLVTRDTHQKKIGDFSG"
     gene            13788..14183
                     /locus_tag="PK679_02495"
     CDS             13788..14183
                     /locus_tag="PK679_02495"
                     /inference="COORDINATES: protein motif:HMM:NF024865.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HPC54859.1"
                     /translation="MTPSPQTSLQVLDTLDTFAKYLGRSDVPAALALLDRNASFVSPD
                     EEAVFRGMTGIGEYLEREKERYRNFRLMNLEAGAVGTVAWVNGYFSAGPDSSGKSYRG
                     RVSCVLKGTGHAWVIVHVHLSCVPDSCPP"
     gene            complement(14245..16125)
                     /locus_tag="PK679_02500"
     CDS             complement(14245..16125)
                     /locus_tag="PK679_02500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004668 - protein-arginine deiminase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HPC54860.1"
                     /translation="MVRIGLVQAPASTDIAANLERNTSMVEEALAQGAHIVCLQELFC
                     FPYFPQYHGFQANQYAQAIPGPITDTISRLARTYGAFIIVPLLEAGEGGELYNSAVIV
                     RPDGKTGRVYRKIHIPNDPLYYEKEYFSPGSRYVVEETPFGRIAVLICYDQWFPEAAR
                     LVTLKGADIIFYPTALGTIRGMEDPLEGDWKGAWESIQRGHAIGNGVHIAAVNRVGRE
                     GDLCFFGGSFICDSFGNVLARAGTGQEVLVADVDLSMNTCVREGWGFLANRRPDTYHG
                     LVSLQDMHLRITPAQAGFRMPAEWEPHQGVWLSWPLDNGTFSDLKAVERAYIRMIRAL
                     VGRERIYLLVQDTEMERRVRDILARECIPGGYVRFFIFPYADVWFRDYGPTFLVHGRD
                     PSLAMVNWTFNAWGEKYPELVSDDRIPAFIEKELQIPSFVPGMVLEGGSIETDGNGTL
                     LVTEQCLLHENRNPALTKGEIEAKLRDYLGVSRVIWLKGGIAGDDTDGHIDDVARFTS
                     PGTVVCAVEEDPHSGNYGILQENLALLKKATSHDGRALSIIPLPMPATGEEVLPASYT
                     NFYIGNGVVMVPTFNDPADRKALQILESLFPGRVVVGIDCSAMITGMGAIHCVTQQFP
                     SL"
     gene            complement(16199..17278)
                     /locus_tag="PK679_02505"
     CDS             complement(16199..17278)
                     /locus_tag="PK679_02505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase"
                     /protein_id="HPC54861.1"
                     /translation="MTTGLIFDREFLLHEQSPSHPERRERLSYTIDQIEEEGLFHHPR
                     IRVSRPPRATREQVERVHHPEYVRFLEEASRRGGFIDFDTVVPRGLLDCALLAAGGAL
                     HAGISVWKGDFTNAFALVRPPGHHARAGTGAGFCYLNNMAIMVRHLQHEGVRKVLVLD
                     WDAHHGDGTQSIFYADPSVLFTSIHQKPLYPGSGDIDETGEGPGLGYTVNMPVPPGTG
                     DVSYHYLFDTVIAPLAREFSPDIIAISAGQDVHFTDPLTGLAVSARGYAELVRKAVML
                     ADSICNGKLVAVLEGGYSVEGGLPYTNLGIIAALAGLPLESIREPAGYQEILLRATDP
                     SAHERVCQTAGELRKLLAPHWNCFS"
     gene            complement(17275..18720)
                     /locus_tag="PK679_02510"
     CDS             complement(17275..18720)
                     /locus_tag="PK679_02510"
                     /inference="COORDINATES: protein motif:HMM:NF014071.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HPC54862.1"
                     /translation="MLIGMDVGGTNTDVAFVDGETASIKVPNSAGIDTALSRISRPGR
                     LAVSTSTPLNHLLAERDRKIVTILIPGMGLFYESGMKGAVNHCGDIVEDIDRDEIDRF
                     LRANPADAVAIAGKFSVRNPALEMAAAECACRYFPKERIALSHPLAVLDFPARIVTTR
                     LNARIREEAFRLVSLIGQRKKDFLFFRGDGGLTTPENVLKDPSVLYNSSPAAVALGVH
                     YLTGLKDCLAVDIGGTTTDLVPLEKGIPCTEELVYGGERTVTRVVKAESLPFGGDSVI
                     ADSIEPKRDGNALAFGGRLPTLTDALNRAGYEIGDFRASLSLRLEHAEKAVDDYCSIV
                     AAAVAAHDPPKIAGCGYLAPILVPEIARRARKPFVIPPHAACANAVGVAVSRVSLTLF
                     AHFDGGRGRVVMNGETGKIDRVGDDDELVAICTAEVKRRALAAGADPRDLDDIRVLHC
                     SSFDVVRGSFRTSRIADIVVQVAPGITAEAR"
     gene            complement(18864..20924)
                     /locus_tag="PK679_02515"
     CDS             complement(18864..20924)
                     /locus_tag="PK679_02515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA synthetase"
                     /protein_id="HPC54863.1"
                     /translation="MIREAEAYIQLSHAISYPGRNSPVAGFVKKFLCGNADLVAWFVI
                     AWHGVSGIPPDLYDRVYSRSLESPEEFWAEAAGKVTWWRQWDRVLDRSNPPFFRWFSG
                     GILNTCYNALDRHVEAGRKDQVALIYDSPVTRTMRKFTYGELLDAVSRCAGGLLELGV
                     RKGDRVVIYMPMIPEAVIGMLACARIGAIHSVVFGGFAPRELATRIRDASPKVLLISS
                     CGIEVTRIIPYKPLIDEALELAGVDIDCCVVVQRPEYEAGMIPGRDRAWSGFMDRAPP
                     AECVPVGATDPLYILYTSGTTGIPKGVVRDNGGHLVALLWSMENIYGMKPGEVFWAAS
                     DVGWVVGHSYIVYGPLAYGCTTIIYEGKSVGTPDPGAFWRVVSQHRVNALFCAPTALR
                     AIRREDPEGSHIRKYDLSSLRTLFLAGERCDPDTLVWARENLSVPAIDHWWQTETGWA
                     IGANPVGISLLPVKPGSCTLPMPGYDVRVLDEAGNEVPAGTTGNIAIRLPLPPGCFTT
                     LWQKDEECRRTYFSTYPGFYLTGDAGYRDKDGYLWIMGRTDDIINTAGHRLSTGAMEE
                     VIASHPDVAECAVAGVADEVKGEVPVGFVVLKANVNRNNGDIARELVQMVRDRIGPIA
                     SFKTAVVVRRLPKTRSGKILRGVMKKIADGKTYSVPPTIEDPAVLAEVAERLSEMGYP
                     RRGP"
     gene            20934..21497
                     /locus_tag="PK679_02520"
     CDS             20934..21497
                     /locus_tag="PK679_02520"
                     /inference="COORDINATES: protein motif:HMM:NF014689.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP family protein"
                     /protein_id="HPC54864.1"
                     /translation="MDPFLILFLGISLAFDCFAVSLSAGSRSPEKRLRIALVLGSCFG
                     VFQGGMFLAGYFSAGFLVYLVSAFDHWVAFGILLVVGLKMVYGGTGAGEGEKVKDYFS
                     PGTLLALSLATSIDALGVGLSFALIGDGMVVMALVAAVVSFLFSVAGTFLGGRLSERF
                     GERFEIIGGMILIVIGTRILLEHMALL"
     gene            21748..22116
                     /locus_tag="PK679_02525"
     CDS             21748..22116
                     /locus_tag="PK679_02525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54865.1"
                     /translation="MTDIYRSIYQKMKKMGILDVKQYAVIENPPYVPLCIDRLSPDTY
                     ALSQNPVVDGLMVADPDIEVRVDHGEETAEPLVCLSRETKKVVYPAPGKVNLAVRNEL
                     SAFLDRWLSDLIAQGFNRYQ"
     gene            22206..22847
                     /locus_tag="PK679_02530"
     CDS             22206..22847
                     /locus_tag="PK679_02530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5591 domain-containing protein"
                     /protein_id="HPC54866.1"
                     /translation="MTGGGIKEQDDSHLTRDGIIINDPPFFLPEFEDAFRFIISTYTP
                     PKREIAIFLPCALRKPYSSSPSHRLFQRIIDSRVLPDTYHIVVFGTCGVVPRELELMY
                     PFAHYHYMLGKCTDNTIREAFLEIETYRLAAYLTKTKDIYRKRVAYCIGPFREAMCRA
                     SRKTGIMLDLLLPSASTLEKNRDPDCPFPEGSLSLQAYLDEFERGLALLSKGR"
     gene            complement(23642..25138)
                     /locus_tag="PK679_02535"
     CDS             complement(23642..25138)
                     /locus_tag="PK679_02535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HPC54867.1"
                     /translation="MIDPVDMAIVIVYFLILVGIGVVASKKIHTMNDYVLAGRSLGFW
                     LFTMLMIGSVCSGMSLLGVSGLGYSYGWPTIWEQIFVPLSIAFCIVFFGVKIHGLAQE
                     WGYLTIQDYLAHRFGSETALRSLSAVSGIIVSLIYLAGQYTAVSIVLMWLFGLPHWIA
                     LITGACIVTIYTVIGGLYAVTWTTLIQGLILIAGVLVMAPLVIMKAGGFMHINEVMAA
                     QNPDFIRLWVDSGLFTPAYIFSFSLLLMVGLACAPHVINNVLAVKNASFFKWAPLVAF
                     CIYGLVMFLLKFGGFAGRVLVSEGIITLPPVKNAGDFVFIYAIQSALPNIVLWGVFAV
                     VVLAAVMSTTDRLMLTIGTYFSWDIFKSLIKPDATDRQVILVSRVSVAAAAILTVLMA
                     LDPPAMLVWLIWAGIGIMFATFAVPLLAGLYWKRATREGALAAMALGLVTSCLAGGLT
                     YFKIMPLPVHFSLFGVLVAIAAMVIVSLMTPPTSPRVLEETKTGFFLK"
     gene            25495..25857
                     /locus_tag="PK679_02540"
     CDS             25495..25857
                     /locus_tag="PK679_02540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54868.1"
                     /translation="MALEEIRRLKRTEEKALEIIAGAEKEAEDILSRAAESADALVSQ
                     AIAEAQREGDARRRASLERAEKEGKEIIQKAVNDAEFLLEMAKKRADKATRCIVDIVT
                     GEPYVLSGPDVQGDAGHR"
     gene            25811..27787
                     /locus_tag="PK679_02545"
     CDS             25811..27787
                     /locus_tag="PK679_02545"
                     /inference="COORDINATES: protein motif:HMM:NF013647.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HPC54869.1"
                     /translation="MFYPARMYRVTLGIDNTRRSAGIGALHETGMLEVIPLREFDPPL
                     QDHLEAGERDLLADRCAEYRVRLDRVLEALYEFPPSPGNFLKELVSPRGHEKYPVTAG
                     TLAELLQEIDSILNTTERALEIRALLMEKDERLGESFRVRSDLELLQVIPFDLSALGE
                     SRFLSISAASAGTETAEEVIARLAETCGDEIYVDSRESGDVTVFVVACISEEKEAVES
                     ILQSPGITPIRIEARQGLPGEVLKATDEEISQLKAERDSLQEELAALRREHETHILAL
                     REELLIRREELDLVTRCGVTGEVTVIQGFVPASALTQIRAGVGEATEEHHFVSVQEPD
                     PEDSSVPVHYENPPFLAPFEYLTTMFARPRYDEIDPTPFVAPIFLIFFGLMLGDAGYG
                     ILIALVGYLIYRGAGRVSTTMRDLSYILTLCGISAIIFGAIQGGWFGDVPQRFFGMTP
                     PFVLIEPLKDPIAFFQISLILGIVHINLGLLLAFYQNFRKKRYRACIFDQGIWYILQP
                     SAGVLLAEFFGWAPVPPWLHFLALAGAALSIAMIFYTRGPMGFFSLTGFLGDWLSYVR
                     ILALALATGGIAMTVNILAQIVGNAGPLLLVPAIIVFLGGQAFNVVIQALGGVIHAIR
                     LQYIEFFGKFYQGGGKAFTPFRVERMYSRRGDGQ"
     gene            27784..29229
                     /locus_tag="PK679_02550"
     CDS             27784..29229
                     /locus_tag="PK679_02550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HPC54870.1"
                     /translation="MTIGLGTALLAIGAGIAAGFSAIGAGIGVGITGAASAGVTAERP
                     EKFGVALIYSAIPQTQAIYGLLVAILILLSGGFLGGLAGDIPVPIGLSAIGAGLAVGI
                     AGLSSIGQGIAASSAVAMTSERPEMFGKGVVFSVICETQAIYGLLVAVLILVFSGLLS
                     GNYIATVASGLAGIGCGLAIGLAGISAIGQGIAASAGVAATGEHPDLFGKGVVFAAIC
                     ETQAIYGLLVAILIMSFTGMFSGNLITTLASGVVAIGCGLASGFAGFSAIGQGIAAAS
                     GIGATAEKPGLFGKGVVFAAICETQAIYGLLVAVLLMSFCGLISGDTTLSLAVGFAAI
                     GGGLAVGLAGLSAIGQGIAAASGIAATSEKEDMFGKGVVFSAVCETQAIYGLLVAILL
                     MAFTGMITHDFVTTVAIGVAAIGAGIAVGLGGLSAIGQGITCASGIAATARRPEAMGR
                     SLVFAAMSETFAIFGLLVAILVLFGLGIFHV"
     gene            29257..29874
                     /locus_tag="PK679_02555"
     CDS             29257..29874
                     /locus_tag="PK679_02555"
                     /inference="COORDINATES: protein motif:HMM:NF014093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HPC54871.1"
                     /translation="MSVEKIEQRILSDAKTEAERILKKAREEADLVIEKARKEAEKRT
                     RQIRTEEDEKTARACTQLLSQSRIEARKVYRNARENAINEVFAGAKAELGKIRENPRY
                     PDIFFRLAAEGIRNLGQDRVELEVHPADRPLAEDFIRKWGKNPGECIISTRTVMTNGG
                     VIVSGPGGTVKVNNTVEARLERMEREIAARVARILFSEGGDAGGR"
     gene            29864..31063
                     /locus_tag="PK679_02560"
     CDS             29864..31063
                     /locus_tag="PK679_02560"
                     /inference="COORDINATES: protein motif:HMM:NF014094.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HPC54872.1"
                     /translation="MAGEDLGSMLDTLSKGLSLDPGLLMIGALAMLLVIVLVIVTFLG
                     YFRVLLTIAQFAYPIARVKAIGNPFIRPETLQRMRETRNIYEACTAVREAGAGLDIPE
                     NARPEDVDRILDAWYINEFNALLGTLPDSIKPFFLAYQGVLEVEQLVKAVRMVYSPWG
                     TAGISSRLIPVGCLTPERLRNLDGASGIRELAARLSGTPYEEALSGIVPLAEQSSSPF
                     PVENTLWRFSLERLNLSRIHIDPSHLSAVAGFLGIFTDVTNILTLLRAKRQGIPADVV
                     SGWFVPGGAVYEEWRLAQLYENRGVKEIINQLAGTDYYTVLSFALSDAEEPDLSMLEI
                     ALDRFLLARVVSLSQVHHLQGGPLIKYAIARRYEVRNLRVLFHSLYEGLSITDVSRFI
                     VTEASLS"
     gene            31060..31359
                     /locus_tag="PK679_02565"
     CDS             31060..31359
                     /locus_tag="PK679_02565"
                     /inference="COORDINATES: protein motif:HMM:NF014092.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HPC54873.1"
                     /translation="MRIAVLGDPRMVRGFALAGIKDVFVAQDPPSARETLVKWLHDPA
                     IGIIVIPARFWSGLRGDIRSVEGSRGGYPVILALPDSSGGADYAGEDYLKMAGLE"
     gene            31367..33142
                     /locus_tag="PK679_02570"
     CDS             31367..33142
                     /locus_tag="PK679_02570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HPC54874.1"
                     /translation="MDGDKKCRGTIIRVTGPVVVADGMAGARMFEIVRVGEEALIGEI
                     IALENDRATIQVYEETAGIRPGEPVTGTGRSLSVALGPGLLGTIFDGIQRPLAEMHQV
                     SGDFIGRGSSVPALDPRKPWTFTPRARPGDRVRGGDVLGVVPESPSVPHLIMVPPALS
                     GTVATIADEGEYTIHDPVCTIRSEGAEVELTMVQYWPVRAGRPISQKLDPVDPLLTGQ
                     RVIDLLFPIAIGGTAAIPGPFGSGKTVVQHQLAKWANADIVIFVGCGERGNEMADVLA
                     EFPRLEDPRTGLPLLNRMVLIANTSNMPVAAREASVYTGMTLAEYYRDMGYKVALMAD
                     STSRWAEAMREISGRLEEMPGEEGYPAYLGSRLADFYERAGRVRTIGTEEREGSISVI
                     GAVSPPGGDFSEPVTQNTLRIVKVFWALDSDLAYRRHFPAINWLSSYSLYTGIVNRWW
                     NENAGPGWESMKSEIMAILQKENELEEMVKLVGPEVLPERDRLTLLEAEVIRESILMQ
                     YAFHPEDTYTSPKKLYRMVEMVFSFFALARRAVSSGVLTETIRSLPVKSRLARMGTVP
                     ENAVDTVFPGIENQMREEFASLGRS"
     gene            33144..34541
                     /locus_tag="PK679_02575"
     CDS             33144..34541
                     /locus_tag="PK679_02575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HPC54875.1"
                     /translation="MQRGAREYRSVTHIHGPIMVVDNVSGVAFGEVVEITLPSGEKRL
                     GQVLESRTNRAIVQVFGTTRDLDTDATTARFTGKTMHIAVTEEMLGRIFDGIARPLDG
                     GAPPLGEEERDIHGSSINPYAREHPRDSIQTGISVIDGMNTLVRGQKLPIFSGAGLPH
                     NLLAAQITRQAKVRGQQELFAVVFAAMGITHEEAAFFVSDFTRTGALERAVIFLNLAD
                     DPAIERIITPRLALTTAEFLAFEKGMHVLVILTDLTNYCEALREISAAREEVPGRRGY
                     PGYMYTDLASIFERAGRIKGRTGSITQIPILTMPDDDITHPVPDLTGYITEGQIVLSR
                     DLHRKGIYPPINPLPCLSRLMQTGIGPDRTREDHAQVNNQLYAAYAQGIKLKGLVAVV
                     GEEGLSETDREYIRFADRFEREFISQGPEEDRSFEATLDRAWDLLSVLPEGELRRIDE
                     SFIRKYHPAYRGQKE"
     gene            34538..35176
                     /locus_tag="PK679_02580"
     CDS             34538..35176
                     /locus_tag="PK679_02580"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR00309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016471 - vacuolar proton-transporting
                     V-type ATPase complex [Evidence IEA];
                     GO_function: GO:0008553 - P-type proton-exporting
                     transporter activity [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HPC54876.1"
                     /translation="MSVQGRSGIRPTRIELLRLKKQELLAQRGHDLLEEKLDAMVVAF
                     FDYRDAYLEQKRRVDETFRSALSALSFAEMLAGTDTVDAVAASSPPLPDIPTGSRLVM
                     GVRVPALPSESFPVHESGYGLLGTPAAIDNATKRFEDLTREILVLAEREGTVRRLSRE
                     ISKTRRRVNALERILLPQLQSTRRYIEMHLEEREREDQFRRKRIKHLKTESP"
     gene            35173..35337
                     /locus_tag="PK679_02585"
     CDS             35173..35337
                     /locus_tag="PK679_02585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54877.1"
                     /translation="MKAAPHDPWIDSFLRRPDVRTKLSFYFFCLQVTIYVTLVAGLFI
                     FMYLVLTRTG"
     gene            complement(35321..36226)
                     /locus_tag="PK679_02590"
     CDS             complement(35321..36226)
                     /locus_tag="PK679_02590"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HPC54878.1"
                     /translation="MFSRILFPTDFSEHAKQTLDCIAGFPGVKEVILLHIIDTSRPGF
                     APWGISMMEEEAKKQLQSECTLLKAQGVNARTIMRTVSHGPVGEMVIRVAEEVDPSMI
                     LVGARGKSILRDILLGSVSGYVLRHSPCSVLIMKYRMVEGFRGKTFEKFCPRILSRVL
                     CPTDFSPPAREALDMVSNLRGISEIILLHVVDSGENEEEIAMRKGEALLEMEKDALSL
                     ARKNIPARCLVKVGNPALEIARCVEEEDVSLVAFSSHGRGWLGGLIPGSTAQEVARVA
                     SRPVLVIRNPDTEKRNPSAAINRSG"
     gene            36602..36928
                     /locus_tag="PK679_02595"
     CDS             36602..36928
                     /locus_tag="PK679_02595"
                     /inference="COORDINATES: protein motif:HMM:NF028309.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit subunit G family protein"
                     /protein_id="HPC54879.1"
                     /translation="MDQESSLLEVVRKKELELKSRIEKATKEAEETIAQARRRAEEIL
                     ESARKRGEEESSRFMGEQEKAMDQEIREIRESSLLERKQVSARAGEQIDKAVELIIGR
                     IVAKGP"
     gene            36928..38841
                     /locus_tag="PK679_02600"
     CDS             36928..38841
                     /locus_tag="PK679_02600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HPC54880.1"
                     /translation="MLQKMKNILVVGPKKDYQQIVDVLYQEGTVHLQDIPFSLDDPVF
                     SPMETGKTEDISAILLKLHGIARILPGKAVEPEIERRTGELRGKTTDELLSEAKEVVR
                     VLESKVRDLATRKGDLELTRTTLDRYAKVMEKIQPLESRLPILEGFEVSVLLIQREYR
                     DVLDLIRPQLKAITNNQFEFIAADLDDTTTAAITVFNKKYSQEVHSFLFSQNVNEVRV
                     PEEYANMHLNEALSLIDNRKRDIAREMEEIDSELGTLAEKWQTELAVYTRLLEDRLEE
                     LRSLNMFGQSDHTIMIKGWIPKKFLKKTREALREKFGDRVVLTEVRVPPEEMENAPTY
                     YDNPRIVKPFEFFMKLVSPPKYIEIDPSPLLALFFPIFFGIIVGDIGYGLCILGFGLA
                     MKKKFQKVEWMQQLMNIMIISSFPTIFFGFLFGEFFGDFGEHIGLLHPVHFLGITWNR
                     VEAMIPLLVLAIAIGVIHIFVGLSIGILNAYARHQKKHLCEKAGMMGVVLGIILLILT
                     FVKVLPSFMMIVSAIILVAFLPLLVYGGGTMGVIEVMSTIGNILSYARIMAIGMASVI
                     LAMVANELGGAIGVLVAGIVIAVLLHALNIILAMFSPSLHSVRLHIVEFYSKFYEGGG
                     TEYRPFGREKKTD"
     gene            38999..39217
                     /locus_tag="PK679_02605"
     CDS             38999..39217
                     /locus_tag="PK679_02605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HPC54881.1"
                     /translation="MAGWEIPLGAAIAFAAGAIGTAWAQSRIGSAGAGTIAERPETSG
                     SIIVLEAIPETLVILGFVVASMIIIMVE"
     gene            39327..39911
                     /locus_tag="PK679_02610"
     CDS             39327..39911
                     /locus_tag="PK679_02610"
                     /inference="COORDINATES: protein motif:HMM:NF014093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033178 - proton-transporting two-sector
                     ATPase complex, catalytic domain [Evidence IEA];
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E family protein"
                     /protein_id="HPC54882.1"
                     /translation="MTYEDLIQSMEAGAEEKIAEIRSNAARQSEGIIQDAEEKAKTIR
                     EEFLARARATVADQRNRLLYKTRLDERSAGIAAKEEILNAVYSRVAGHLGKIREKNDY
                     RSLFSRLLSESLEEMGENSVVLHVDPRDEALCREVVSQMKGNFTINPDIKTWGGVVVS
                     SPDDQIRIHNTLESRLERAKILTKREICRILFGE"
     gene            39914..40963
                     /locus_tag="PK679_02615"
     CDS             39914..40963
                     /locus_tag="PK679_02615"
                     /inference="COORDINATES: protein motif:HMM:NF014094.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HPC54883.1"
                     /translation="MDLGYINARVRGMHSRLLGPKAFDALMIQQDIPSLVSELEKTPY
                     RDEIQEASVLYPGLKGIETALRLNLVHTCQKILSLVEGSDAEQLVRIILARWDVHNIK
                     TVMRGKHLHVSPEEIEECLIPAGSLGEPLLVELIKQPDVRGVVDLLATWDVPFARPLT
                     QYFDEYASARELSILEYALDRFYYENSLALLKAGKSDHEVMRTLLMQEIDSLNLKNAI
                     RMNRDRVDPETAEKYFLPGGEHITSEKFLALVKAGTIDEIVGNVEGTPYYFLAPLIPE
                     AMRTGTFSVLEKELDEYLTRKGTGVFRSDPLGGAVVIGYLWAKQNEIINIRIIARCKD
                     ARIPDAELEKELRHV"
     gene            40956..41276
                     /locus_tag="PK679_02620"
     CDS             40956..41276
                     /locus_tag="PK679_02620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HPC54884.1"
                     /translation="MYKFMVVTDPDTAAGFRLAGAEVIEAADAQEARKIIPPLLHRDD
                     TGIIAVNEDFIQALDEKLMNRIERTYRPIIIPIPKRARTGGGPGYLENLLRRAVGYNI
                     VVRR"
     gene            41278..43017
                     /locus_tag="PK679_02625"
     CDS             41278..43017
                     /locus_tag="PK679_02625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HPC54885.1"
                     /translation="MIQGTISRISGPVVIAEGMRGSKMYDVVNVGTLDLPGEIIRLEG
                     DWAVVQVYEDTTGLSIGEPVKNTEQPLSVELGPGLISSIFDGVQRPLPELAKKSGSFI
                     SRGISATGLSREREWDFEPAIAEGTQVKGGEILGSVREFHFTHHILVPPGVTGTIKKI
                     RKGRFRVTDTICELDSGTELTMLQRWPVRKGRPYVKKLDPTVPLVTGQRIFDCLFPLT
                     KGGTAMIPGGFGTGKTVSEQTLAKWADAQVIIYIGCGERGNEMTDVLSEFPELVDPRT
                     GLPLIQRTILIANTSNMPVAAREASIYTGITMAEYYRDMGYDVALMADSTSRWGEALR
                     EVSGRLEEMPGEEGYPAYLATRLAAFYERAGRVICLGPEGRTGSVTIVGAVSPPGGDF
                     SEPITQNTLRIAGTFWALDTNLAYRRHFPSVNWIKSYSLYLDSVEKWFTEMMAGNWRE
                     LRDKTMYLLQKEVELQEIVQLVGPDALPESEKAILEVTRMIREDFLQQSAYSDTDSFC
                     PLDKQFWMLATIISYYEAAEEAMNRGVSLKQISSLPLRAEIARMKEISEVEQIRQLAD
                     RVKAQIGALEVEH"
     gene            43017..44414
                     /locus_tag="PK679_02630"
     CDS             43017..44414
                     /locus_tag="PK679_02630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HPC54886.1"
                     /translation="MPPVSLVDREFRTVSYVSGPLIFVERPKGVSFGETARITLPDGE
                     VRNGQVLDVSRELAVVQVFEGTSGVDNKATSVRFTGQSPCIDVSLDMLGRVFSGVGRP
                     RDGRPEIIPEDTVDISGMPINPYARDKPSDFIQTGMSAIDGLNTLVRGQKLPIFSGSG
                     LPANKLAAQIARQARVLGREESFAVVFVAMGITHKEASYFMNEFERTGALERVVFFQN
                     LADDPTIERIATPRCALSVAEFLAYTHHLHVLVILTDMTNYCEALREISTAREEVPGR
                     RGYPGYMYTDLASIYERAGRIKGTTGSITQIPILTMPDDDITHPVPDLTGYITEGQIV
                     LSRDLYRRGADPPIDVLPCLSRLMNLGIGPGKTREDHRNVADQLYASYAYGRDLRRLV
                     AIVGEEALTELDKVYLSFADDFEKKFVTQGSANRSIEETLTIGWELLAKLPEDELKRI
                     KLEYIRKYHPRYRAG"
     gene            44420..45097
                     /locus_tag="PK679_02635"
     CDS             44420..45097
                     /locus_tag="PK679_02635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HPC54887.1"
                     /translation="MEQVNPTRMELIRKRAQIKLAEQGRDLLREKMDALIQEFFRIMG
                     SVSRSREELETVAETAFRSLVIAQAVDDPVTLRSVSFTTRKQIALDIGGKNIMGVPVP
                     IIEKKRFSLPSIERGYSILGVSGRIDETAERFESEIDLIIGLAETETALRRLGHEIQM
                     NRRRVNALEQVLIPELKRQAKYIKITIEEREREDLFRLKKVKKILNRKKRGQGRSPSG
                     GQMSRKG"
     gene            complement(45094..45225)
                     /locus_tag="PK679_02640"
     CDS             complement(45094..45225)
                     /locus_tag="PK679_02640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54888.1"
                     /translation="MRSYRHLRHVLVTMRTGQVARREPGLKTLIDVCERVGGKEGQN"
     gene            complement(45389..45718)
                     /locus_tag="PK679_02645"
     CDS             complement(45389..45718)
                     /locus_tag="PK679_02645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54889.1"
                     /translation="MPDVSRTEIGRRLFSLQKEKSIEQALEKIRKNLGEEWRDFSQEE
                     IDLLKHALGDAWVFIERDVWEKIAFSRLSRRDVLDLIAIGRESRAKEIDQRVAVEKAS
                     RVLRATM"
     gene            45945..47852
                     /locus_tag="PK679_02650"
     CDS             45945..47852
                     /locus_tag="PK679_02650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HPC54890.1"
                     /translation="MLTLPFLVVFPALVAALLLLISRDSRRRLVVWAGAAVTGIASLS
                     LLFITPESGPLFYPVGYEVLSEGMFVAELAIAVFLIYLGIKYRKYLAIFLILFQAALL
                     VFFETGRGSVVHHIMPDLFIDQFSLIMALIIGIIGSLICVYSLGYMATYHERHPNVPD
                     RRRSFFFLVFIFLSAMFGLVFSDYLPWIFFFWEITTLCSFLLIGYSKTDESIKNAFLA
                     LNMNILGGIAFAGALLYIIAVNPGGDLLHLHSLIQSGHAIALVPAVLIGFAGITKSAL
                     MPFSGWLVGAMVAPTPVSALLHSSTMVKAGVYIIVRFAPVLTGTMEGLIIGLVGGVTF
                     LLASAIAISQSNAKKVLAYSTIANLGLIVACAGVGTYKLIWAAILLIIFHAIAKSLLF
                     LCVGTVEHRIGSRDIEDMTGLIVRMPRISVMMFIGIAGMFLAPFGMLISKWAAIEAFI
                     DAQFGLAFVAILAFGGSLTVLFWSKWMGKIISMCPVAERVENNIPTEKWMVLSILTAL
                     TVLVCLIFPIISAHLIEPFVLAVYGQTTRLSQDNITIMAMMLFLLMIMPFSLLLYRND
                     KRIVPAYMGGRPATADLTFQGSLGMKQHVGLCNYYFEEVFGEQKLFMAGSALCFGLIL
                     LVGTLTAGVAL"
     gene            47849..48715
                     /locus_tag="PK679_02655"
     CDS             47849..48715
                     /locus_tag="PK679_02655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="HPC54891.1"
                     /translation="MMHIGNALLFIVLAPLIGGLVAGIDRKVTARMQGRVGPPLLQPF
                     YDVGKLFQKEQILVTPSQNFYITAYLVFIVVSGALFFAGGDLLLVIFAFTLAHIFLVL
                     GAYSSYSPYSFIGAERELIQIIAYEPMIILSAVGMYLVTRSFYVADIMAAEFPLIYYL
                     PGVFIGFLMVLTIKLRKSPFDLSTSHHAHQEIVKGVTTEFSGPMLGRVEIAHWYENVF
                     LLGFIYLFFAWNPLVAILVLAIVYFIEIVIDNTFSRVTWQLTLKSAWIIAGLMGLANL
                     GILYYLSGVVPA"
     gene            48712..49185
                     /locus_tag="PK679_02660"
     CDS             48712..49185
                     /locus_tag="PK679_02660"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990204 - oxidoreductase complex
                     [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B family
                     protein"
                     /protein_id="HPC54892.1"
                     /translation="MSYLSRSPWVLHYDASSCNGCDIEVLACLSPLYDVERFGIINTG
                     NPKHADVLVITGGINEQNREVVRNIYDQMPDPKVVVAVGICACTGGVFRECYNVVGGI
                     DCIIPVDVYVPGCAARPESIIDGIVRALAVLEDKKRRMENAGGKEQAGSPAGGAQ"
     gene            49182..49562
                     /locus_tag="PK679_02665"
     CDS             49182..49562
                     /locus_tag="PK679_02665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HPC54893.1"
                     /translation="MTQDDQQTTIIEPLHLLGKVEEFKKKGCRLVQMHCTKAGDTFEI
                     NYSFDINYEFSNIRIITDGKTEIPSISGIYWGAFVYENEMHDLFGIRFAGMNIDFSGN
                     LIRTAKKNPFADPSFRGEKPCPDA"
     gene            49547..50626
                     /locus_tag="PK679_02670"
     CDS             49547..50626
                     /locus_tag="PK679_02670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent hydrogenase large subunit"
                     /protein_id="HPC54894.1"
                     /translation="MPRRIVVPFGPQHPVLPEPIHLDLVLKDEHVEEALPSIGYIHRG
                     LETLVTRREYPEYVYIAERTCGICSFIHGMTYCQAVEKLVDCSVPERALFLRTIWSEY
                     SRLHSHLLWLGLFADALGFENLFMASWRLRESVLDVLEETTGGRVIQGSCKVGGVRRD
                     IPGETLERMRSGLDTIEREAGEIADVFLRDDSIISRTRGIGVLSREDAYALGAVGPTA
                     RASGVGIDLRKTGYAAYGRLSFSPVVETAGDCHARCIVRVKEIFTSIDLIRQAIAKIP
                     DGPVEEKPKKNPEGDYFARSEQPRGELVHYVKGDGSRHLVRSRIRTPTLTNLPSLVRM
                     LKGCNLADVPVIVLSIDPCIGCAER"
     gene            50634..51047
                     /locus_tag="PK679_02675"
     CDS             50634..51047
                     /locus_tag="PK679_02675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC54895.1"
                     /translation="MAFFEMAKTAIGTVLRKPATRRYPSVAPKSTPLTRGRVSIDPSR
                     CISCGMCMKKCPSGAICVRKEEKTWSIDRLKCVVCNCCVEVCPAHCLTMETSYFPCVT
                     EHSAIDVHAITYVKPERPKRPETGEKAGEGTAESS"
     gene            complement(51087..51764)
                     /locus_tag="PK679_02680"
     CDS             complement(51087..51764)
                     /locus_tag="PK679_02680"
                     /inference="COORDINATES: protein motif:HMM:NF016382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease V"
                     /protein_id="HPC54896.1"
                     /translation="MGYDQDPTFWMEARRLQEEVARFASGQQPVDTSVIQTVGGADVS
                     YGGDNAYACFIILEYGSLRGRTRAAATSKVRFPYVPGYFAFREIPALLAALRLVPALP
                     DLFLVHGHGYAHPRRAGIATHLGVLLGVPTIGVAGNLLSGMQAETPPDRIGETAPVRM
                     GGEVVGAMVRTCQGKAPLIISPGFRTTLPDAVSIVLHCTTDHRFPEPLYLADRCAGRF
                     RKDVCRG"
     gene            51911..52711
                     /locus_tag="PK679_02685"
     CDS             51911..52711
                     /locus_tag="PK679_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FHA domain-containing protein"
                     /protein_id="HPC54897.1"
                     /translation="MELRKPPGTDDMTKTVIREEVPDYFQELSEYLEVLSNSQRLKIL
                     KMLEKKPRDVRTIASEIETSYENTKKHLDRLMSMGLIRKEVGLGPQTSKGVHPVWKYS
                     LVPGAMEAIIRNLGFFSNMRIQLSDLDLKRRLEDVRSAIEGEITGNQPVLIVLGGPED
                     GKFFFIGEKGARIGRIDQTVKEDPSGDVVLGRDYSSVSRVSRPHAVIRREGKKWLIED
                     RGSTGGTFLNGNALQKGVATEVSDGDVIELAKGPAGARLLVILPIGAS"
     gene            52735..>53443
                     /locus_tag="PK679_02690"
     CDS             52735..>53443
                     /locus_tag="PK679_02690"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC54898.1"
                     /translation="MNTGPSIPVVTILILAVLLIIGPACAVKTYTISASAGEGGVISP
                     SGEVRVDHGGSQIFIIEAANGFTIGDVRVDGKSLGPISFYTFTNVREDHSIAASFLPL
                     TGTLEIDSSPSGASVFLDGTYIGKTTPTGPARFDGITPGTHSLRLVLEGYEDYATDIL
                     ISEGSTTTVPLVTLVPIPTTATTSPTPTRTPTPTPTPATTTTTSPTPTRTPTPTPSPT
                     PTPTTTATTSPTPTQTPT"
     assembly_gap    53444..53543
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <53544..54938
                     /locus_tag="PK679_02695"
     CDS             <53544..54938
                     /locus_tag="PK679_02695"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: protein motif:HMM:NF012298.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HPC54899.1"
                     /translation="SPLRTLLVLVTGLLATVILSRDVLSSSREPLIPLKKRIIALFVL
                     GIPCVAQAMALHATIRSGGAGGALFFDLAVVVIPVSLYLVLSGTGLVIGALLSWPFRG
                     MLKAHTVAGVVMVFLSLFSLARGDDPAPAITGLFLLSGLLAALGARWQEGLYPAGKGH
                     GTRGEAENRVAGDSSDVTRALPSRGQGMLPPDLADKYSSIEFIGSGGLAHVYRAVNSA
                     TGQEVALKIPLRSDETTGKSFMKEIRGWEGLYHPNIVRVNEANILPIPYIEMEYIRRT
                     LADVPKPLPVREAARIARDLCRGLSHAHERQVIHRDIKPHNIMITDDGIPKISDWGMS
                     KIMGIPGMPTITGFSLAYAAPEQLAPGTFGETDRRTDIYQLGCVLYELLTGRVPFPGT
                     DMAQVTAAILSATPPLPSELNPAARPLDTIVMRCLAKKPEDRYQDARDLERDLDQFLS
                     GTSPYDDFDIFEDT"
     gene            complement(55445..57499)
                     /locus_tag="PK679_02700"
     CDS             complement(55445..57499)
                     /locus_tag="PK679_02700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HPC54900.1"
                     /translation="MIAFPNVIERLGNAGIEFPAYAIARTPEDAARAADAIGYPVVLK
                     ILSDQVVHKTDVGGVVTGIGSAEEAARACEKMLRDVPSRVPGAVVQGVLVQAQVPPGL
                     EIIVGGKTDPTFGKVILCGMGGVLVELLRDVSMRVLPVGKDQVREMVHEMRGYPLIRG
                     FRGSPPLDEEALVDTIFSLSEVFFRDDTLLEFDCNPVILFRKGCKVVDIRAFSGNAAS
                     AREAVSTMPVDCGIFTPRSVAVIGASADPAKIGYVVLRNLLSFSGAVYPVNPRHTEIL
                     GKKVYRTVGEIPGNVDAAVVAVPAPAVPGVIRECGEKKIPLAIILSSGFREDDEEGAK
                     REEEVLSIARSAGMRIIGPNCLGIIVPRLGLNATFDPVMPRNGPLGFISQSGAVITTI
                     VDWSVPEQIGFSMIISVGNQADLGFVDYLRILEKDPGTRAIILYIEEIRKGREFLRTV
                     AEITPKVPVIAFKSGSSRLGRKAAASHTGSLAGNYEVYQAAFRQAGIIPVYSIEEAFD
                     VAELLASEGYPEGNRGIVVTTAGGFAVMASDFADRYAIDLVPLPEKMREELDSFLPPM
                     WSRENPVDIIGDGGVERYARVFDVMTRFQDDWDIAIIIAVPSALLDPVHLGSEISRFS
                     KATRKVTIGCLLGGESMRAGERVLREKHIPNYREIEAAFRAAGRALQSRMKPGRSQAG
                     IR"
     gene            57687..59012
                     /locus_tag="PK679_02705"
     CDS             57687..59012
                     /locus_tag="PK679_02705"
                     /inference="COORDINATES: protein motif:HMM:NF020804.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC54901.1"
                     /translation="MDKKDGYRRKKRIPSVPDKHLDTNPPFVVGEIPSALSDAIRAYI
                     ERKTGKAWGDPTVLERLMRAIVAQKSAYWKKSQKKVSYRKGYQVLGYLVYHFPVYYAQ
                     GMYLMEDLARRGLVFPSMRILDAGTGPGTLPLAIADFMESREGLSAEVFSIEQSEEFI
                     EAYTFLAEQTASEKSSVCLHRPLQKDIRFLDPDDIPPSLDLIIFQNVLNEIPSQNPAE
                     KGELVRKFAPKLSERGCILLVEPADLDNSQELRRVASSASGKDLFIHAPCRFLWGQAC
                     RGECCWSFETRPPIRPPPFMQDLARGREGFRFRNVDIKYSYSLLRKIPPPRVPGIPLS
                     AKHYVRLSTLGRHVDRRIRVAATIASGDLGDSVTHVFFVCDGSPGAPAYAVLPRYHVS
                     DKNRWLLSAPYGDIAEFSPVLVRYNPRYRAYNLLVTRNSMVRPFTAPDS"
     gene            59176..60072
                     /gene="pyrB"
                     /locus_tag="PK679_02710"
     CDS             59176..60072
                     /gene="pyrB"
                     /locus_tag="PK679_02710"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HPC54902.1"
                     /translation="MRHIISIRDLGKEEIGRILDEAAAIQSRSYDPSALKGKLLGLLF
                     FEPSTRTRMSFAAAMARLGGNFLSMDSVEASSMAKGETLADTIRVVSGYVDAIVLRHP
                     KEGAARLASEFATVPVINAGDGAGQHPSQTLLDLFTIRQSMPLEGIHVGLLGDLRYGR
                     TAHSLTHALSLYNVTIHTITPKGLELPAGLATELRDAGTEVIEHGDIASCIRDLDVLY
                     VTRIQRERFPDAASYFKVASSYRVTPELLTGTKNHFIVLHPLPRLDEIDPRVDELPCA
                     RYFEQSANGIAVRMAMLLRVMT"
     gene            60069..60539
                     /gene="pyrI"
                     /locus_tag="PK679_02715"
     CDS             60069..60539
                     /gene="pyrI"
                     /locus_tag="PK679_02715"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HPC54903.1"
                     /translation="MTREKDARAGLLISPIENGTVIDHITAGEALNVLRIIGITGTTH
                     ESISVATNVESKKIGTKDIVKIKNRELRKEEVDRIALIAPKASINIIRNYKVWDKKGV
                     EIPDRVVGIVRCPNPGCISNTNEPIQSCFLVQKKGLRCLYCDWLITKDITSHIM"
     gene            complement(60866..64588)
                     /locus_tag="PK679_02720"
     CDS             complement(60866..64588)
                     /locus_tag="PK679_02720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobaltochelatase subunit CobN"
                     /protein_id="HPC54904.1"
                     /translation="MRISAIVWGSELPLLREGAADEGIDLNAWATFRLRDPENLSSCI
                     ASLAESDIIILHPTQESYWDTLIPALPAGVPVISYGTDQSFWSLSNQPLSVTAKVNAY
                     FSYGGTSNMVNLLRFLRSAIMREPVHFEEPALDLWEGIYHPDAPRIFTSAGEYWEWRG
                     RKHPHAIGILFYRIYWSNGDLDAVNALIRECEREHDVIAAFSVGTGDATAGSRDAASV
                     VREYFSGVDAIICLPSSALSHDAGEPVRAFTELGVPVIHPLVLYYRTCQEWQEKQDGI
                     GSTELGWAIILPEMYGMTGMIPVASAMREGPEGPEHAWHMPIPERIEALVARVKALIR
                     LREKPDREKRVAFILNSSACASVEANVGAAAHLDSLESVVRILSRMREEGFLVEVPES
                     GEELARLILGRRAINEFRWTTVEDIIARGGALGMVDPETYREWFRELPVDLRNRVIAT
                     WGEPPGQEKDGVPPAMLYQGRMIIPGVRLGNAIVLTQPKRGCAGSRCDGRVCRILHDP
                     HVPPPHHYIAVYRYIAREFGADVVIHVGTHGTLEFLPGKSVALSAECLPDAVLGDIPL
                     LYIYNSDNPSEGTIAKRRAYATLVDHLQTVMAPGSPYGVLKELEEMVAAFRKFGDTDR
                     ARAHALRHQILETLEREGFTRELGYSDLREMSGDFNAVLAKVDHLLSGMYATRIPEGM
                     HIFGDIPKEKRRARFIASILNHDGHIHALVARMMGLDMRISPSESALLGVLDRFAEDI
                     VAGILAGDEPSRVAAAVLGEKCADIDNVGLSRLRDEVSEVSRRLDLSDEIGSLLSGAR
                     GRFIPPGPSGLLSRGKIEILPTGRNFYSLDPSAVPTPAAWTIGSRLADLLIDKYRNEN
                     GRYPENVALLWMASDIMWAEGEQMAQALALIGVEPEYEHGKLRGFRVVPLERLGRPRI
                     DITVRLSGILRDCFFGCVEFLDDAIRKVASLDEPPESNYLRKKAADGKVTPRIFGAPR
                     GTYGTGVNLAVYASAWETAADLGDIFIYWNGYSYGRGNFGGEARQDLVRQLANVDVTF
                     NKVVTDEYDLLGCCCYFGSHGGITAAAREVSGREVPAYYGDTRNTAAVEVRTLAEEIR
                     RVVRTKLLNPQYIAGLREHGYSGAAELSRRAGRVYGWDATTGEVDDRIFDDIARTFLI
                     DRENREFFREHNIWALEEMTRRLLEANARGMWDADEDVIQAIRDIYLDIEGDLEEEMG
                     TSRGDRQGGAVSPVITDEMRAWKEKIGHLKHRTSVP"
     gene            complement(64590..65366)
                     /locus_tag="PK679_02725"
     CDS             complement(64590..65366)
                     /locus_tag="PK679_02725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC54905.1"
                     /translation="MRLEVRDLSFTYEKRRVLDRVSLSVDEGEVVGILGPNGSGKTTL
                     IKCINHILVPEGRVTFGEREVSAMSPMERARLMAYVPQALSIGMAMTVFESVLMGRRP
                     HVSWGIGEGDIARVTAVLEDLGLSQLAFRNATQISGGERQKVMIARALVQEPLLLLLD
                     EPTSALDLRHQLEVMEIVRAHAAKKKTGVIMAIHDLNLASRFCDRVLVLSGGRVRGEG
                     RPADVLTEDLVRDVYGVKVRVDRADGFSHIIAIEPAREGP"
     gene            complement(65363..66424)
                     /locus_tag="PK679_02730"
     CDS             complement(65363..66424)
                     /locus_tag="PK679_02730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HPC54906.1"
                     /translation="MEGGKETVAAAFRKTQVRRVLFLVTLLVLAFLLAIASIVIGSAG
                     LGAADVMTAVLAGIAPGTFSSDPMAHTIVWDLRLHRVLFALVAGFGLAVAGAVMQGVL
                     RNPLASPFTLGIASAASFGAALAIIVIPAVVFSDTLVVISAFTMSLLAAGAIYGLSRI
                     RGVSSESMVLAGIILMYLFGAMTSFLQYAGTTEQLQAVVFWMFGSLQRTSWEKLALVS
                     IVVAVVTPLLVWKSWDLNALSMGDHVAQSLGVRVGQSRTLNMVAASLITAAVICFTGT
                     IGFIGLVSPHITRLAIGGDHRYLIVGSGLVGALILLASDSLGRTILAPQIIPVGIMTS
                     FIGIPFFLYLFMRRREEYW"
     gene            complement(66438..67679)
                     /locus_tag="PK679_02735"
     CDS             complement(66438..67679)
                     /locus_tag="PK679_02735"
                     /inference="COORDINATES: protein motif:HMM:NF013648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HPC54907.1"
                     /translation="MEKTGREERFAMTPRSLLLVAAAFILITCTIVSAGLPGDPDSDG
                     VITRDELAGQVIAAMESGKPLSGQEFQDLRDAAWIYLHWDGKARTVTDSTGRAVTLSR
                     PLRRIIVMNSETLETMRSLGVGRESVIAVDKYNAHKPEFFPEYAGYPSVGSVWAPDYE
                     KIISLQPDAIFLYASVSTAECDEIEKRVKTSLPGTAVFRFDCYLPETYLGDSQNIARI
                     FGREHDFERLSEFYTQALGKVKRVAAAGDPPLVYLETWNDFKSASRGSGYHDKITMAG
                     GTNIFADSPAEYPEVDPESIVARKPDVIVKLAGSGKYIFGGYSGENSTRFAEVYNAIL
                     ARPGWNSLPAVRNGRVYVLHNGILGGPQYIIGVTYMARWFHPQQAGDLDPEGLHRRYL
                     EEFQGLAPSLARPDMFIYPVD"
     gene            complement(67643..68164)
                     /locus_tag="PK679_02740"
     CDS             complement(67643..68164)
                     /locus_tag="PK679_02740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54908.1"
                     /translation="MNRWYQVACVALLASLLVVPEAMAASVERTVIPVENTTYRVILH
                     LPDEMVAGISESIPAGYEVGDISVPPGQFRIDGNTLYIAVLGERNVSYLLKGQENPEK
                     AIRGSWADIATGESGGISAPGESGSPAGGDQQKDTGSPVKKAGLNLILPFVAAMAAIL
                     GAWKRREGRNGSP"
     gene            68417..69373
                     /locus_tag="PK679_02745"
     CDS             68417..69373
                     /locus_tag="PK679_02745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC54909.1"
                     /translation="MTIIETSGLTKYYGDLCAVDHLDLSVGNEIFGLLGPNGSGKTTT
                     VLMLTTLLEPTGGSARICGYDTREEAREVRRQISYVPQEMAVDIKLTGRENVAFFAKL
                     YGIPRRDEAVDRVLSMMDLSERADDLVRTYSGGMRRRLELAQALVHEPKVLFLDEPTI
                     GLDVAARRKIWEHIRTLKSRGMTIFVTTHYMDEADHSCDRVAILDRGRVIAVDSPSAL
                     RARVGNDIISARVRGQIGDTFPEGITHLGERENGEIVFSTDHGSEKVPVLFHWLEKRG
                     VSVQSISVREPTLDDVFLSLVTQREEGHGFDDHKFRTMLRRR"
     gene            69373..70098
                     /locus_tag="PK679_02750"
     CDS             69373..70098
                     /locus_tag="PK679_02750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC54910.1"
                     /translation="MKDILYYFERDMLRWIRGRISVISALIMPAAWLIFVGLALPTTF
                     SEHYIDFITPGILVLTMLGASLQGGSLLIFDKILGFLNKFLALPSSRESILLGKILFI
                     TTRGLIQATVILVLAWALGASLLSPAGILLSYGILALFGILLSAFSTTIALYLSDHDS
                     YAAFNAMVSMPLFFTSSALMPYSVMPSWLAPIAYWNPVSFAIDAIRSLQEGVLAWTRI
                     GGLAVLAALVVAFCVQKFRKVTV"
     gene            70447..70773
                     /locus_tag="PK679_02755"
     CDS             70447..70773
                     /locus_tag="PK679_02755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54911.1"
                     /translation="MKLAAEAKGGSTLDIKKDACLFRAQRGPPGSPYSRGKDLYVHER
                     KGQTPLYYLHRWSVNAGEKESIVPISPIMAARFLEERGLVCPDLGHQRGAEILRRWGY
                     GILEEF"
BASE COUNT        15442 a        20341 c        19716 g        15218 t
ORIGIN      
        1 ccagtacagg aacttctgct ctcccatgcc tcccacagct ctgcaccggg gcacggatgc
       61 ccgcaagttg cccaccggca caaatcccat ggtcatccgg gtcatcacca tggcagcagt
      121 cgcgatggcc gtcatcgacg gcatcgttgt cagcattgcg ctgccgacga taaccagggc
      181 tttttccgct gatattgcac agtcccagtg gatattgacg ggatacctgg tcaccgagac
      241 gagtcttctc ctcattttcg gaagagtatc ggaattcata ggaaaaaaga ggctttttct
      301 tgccgggctt atcctcttta caacctcgtc catcgcgtgc gggctttcct cgagcctgtg
      361 ggacctcgtc atcttccgcg ccctgcaggc tgcagggtcg gcgatgatct tttcgatttg
      421 cgccgccatc ctctacgaga catcgggacc cggtgagcag gggcgggtga tgggatacat
      481 agggacgaca actgcggcag ccgcagtcgc agctcccctt cttgggggaa tcatcaccgg
      541 ctctctgggt tgggaataca tctttttcat caacggcccg atagggctga caggaatcgc
      601 cctcttcctc ctgttgtcac ccccggaaag tgcgtccgcg aatacttttt ccatggactg
      661 gcccggggct gcatccctcg tctcttttct cgtctttttg gtcctctccc ttgcagaggt
      721 ctccccggga cacttccatg cacccggagt cgtctttttc cttttcctgt ctgttctttc
      781 tctctttctc ttcatcatgg cagagaggaa gagtccctgc cccctgcttg atctcaccct
      841 tttccgggac ccccgtttcc tgctgccgaa catgtccatg gcatgcgttt acatcgcgtt
      901 cttcatgctc tacctcgtcg gaccgttcta cctcgaaggc gcgctgggca tggatcccct
      961 gggggtcggt ttcgtattcc ttgtcatacc cgtcatcatc atcgttggat cgcctgctgc
     1021 cggtctcctc tatgacaggc ggaatgcgag aacactgccg gcatggggca ttggcatcgc
     1081 cggggcctcg ctctttcttt tgagttttgc agtcctcgtg agggaaatag cgctgataat
     1141 agctcttttt gtccccctct ccctcggcat atcactcttc cttgccccga atgcaacaga
     1201 gatcatgcga tccctgcccc ttgaaagggt atcccttgca tcgagcatga gtgccactct
     1261 caagaacctg ggcatgattg cagggatctc tctctctgcc ctctttctct cgctggaact
     1321 ttctgcatac gggtattcgc tgtccttcca ggatgccgat cccgttatcc tctccttctc
     1381 catccagaaa attctcgtta cgggttccat tttctgcgcc atcggggcca tcctctccct
     1441 ggtgagcacc cgttcaccgg gggaacggta agtgccggtt gagttggacc ggaacgaaaa
     1501 acatgcgtgc aaagagcaca gcaactggtc cgggttaccc ccggcctctg aacgggtata
     1561 cagcaggccg gggcacttct ccggagtgtg gaaacgatag gcctccctgc atccgttccc
     1621 cgaccattaa gtcactacca cgatgagaat ggattgggtt tattttcccg gaaaaagacc
     1681 tctttctttc tcatcagggg aaaaatgaag ggtttttgcc ggagatgtca cggcctctcc
     1741 ctaaagaccc ggtaaatctg gatctttccg cgtttcatca gttttcccgg catttgcttc
     1801 ccgtgaaaca aggcagaaaa tacccccgat cagcatgatg atgtcgagtg ggggcaggac
     1861 acttgcgata atcgcatata tccctgcacg ggaaaagtcc tttttctctg tcgagaaaag
     1921 tgcaaggaaa cccatgacga gcccggcaat cctgacagcg gcaagtgctg caacgatgac
     1981 aagcggtatg gtcagggaga ccccgagggt agaaaatacc cctgcggtat agacagccac
     2041 ccctaccact gcgaggagaa ggagaacgag aatgcctatg acgagggaga cgaggatcag
     2101 gatctttcct acttttgcct ccgatgaaag gccttcgata ttgagcatct ctctatcact
     2161 ctgatgtatg taggagcagg gtgcgcatta acttatggcg tctccatctg gcccgggaga
     2221 ctcaccaatc gtcatgaatg tcacgattcc tcgtcctgta ccgcaggaca gaaattgcag
     2281 agcgcaaaga aaacatcctt ctccttgtcc ctgatgggac agtaaaactt cccgttgttt
     2341 tccctgactg agaggccacc gggaaatggt gtcccgaccg gatgtcccgg cctctcgagg
     2401 acaaacatcg cgaacccggc aaggatatag tagaagaggc gatgcctggg cgaatggaac
     2461 tgggggaggt attcccggtg ggactcaaag acaaagcaac cgtccgggac catggaaaag
     2521 taggaatcgt agacgtcctt ttccctgatg ggctggacca tgcgggagaa ttctccgcgg
     2581 gcgcacatta acaggagctc gtggtgtgca tcaacgatct gtccgagcag gtagggtgca
     2641 gcgactttcc tgtaccgggg gggaagacga tggacttcgt accgtacccg tcccatgatg
     2701 acctggaggt caaagaggga gaacgtggag atctcctgtg ccatgagagt tcctgcctct
     2761 ccacgggtct gcgcagcaga tatcctccgg caggaccggc agatctcctc gtatattggg
     2821 gtgtctttct ggtgcatctt gtcaatcagg tattccgggt gtttttcctc cggacacggt
     2881 aaagcagcgc cattcccccc atcgccgcaa ggggtgtgag gagaaatccg gctgcccgtg
     2941 tcggttcagg tccttgtgcc tgcaggggtt tttccttatt ttcctgtgtc tctgccggtg
     3001 acttgattcc ggtgggtgca gtaaaaccac ccacgggggg attcacgtgg atgacaaaac
     3061 tggataccgg ttgtatcccc gttgcaggcg ttgccccggc acaggtatcg ggggccgcct
     3121 ctcccgaaag gtagagaaca ctgatccatg acccgtcgtt tctcccggaa tagcgcgccg
     3181 actctccatt gttcagggac tgttccagca ggacggtatc cccgcttttt atgacgaccc
     3241 gggccgagag tgccttgcat acggaaccgc tgcaggtcga acagtcggga agggtcgaat
     3301 aggcgaactg gtaatcggcc ccgagatcga gggggatagt ccttggatca ccgtaaatgt
     3361 ccgatacaag gtatgtacca ctcccggggg gaacgaccac gagggcgagt gctgcccacc
     3421 gcccccccgt gccaccgagg atggtagccg cgaccagatc gccgttatga aacgtattga
     3481 aggctccctc gtcgggcacc gttccgacga cctggagggg agcgatggat gaaaaagaac
     3541 acgttggagt tcccccggag taactgcatc catactgcga ttccgccctg atagtcaggg
     3601 tgagggaaag agggtccatg gccgttaccc tgccaaggta cgtggtctcc tgaacaaggg
     3661 cagacgcatg tgcgacaaaa cacagcgaaa cgagcacgag agaaagggtc acgaggtaat
     3721 gttcattctt gaccattttt gaccatctcc gaaagggtca ggtatccatg taagggtgga
     3781 caccctgcca gaataacttt ccgaccagca ggaagaaagt ggagacgtca cagacagaat
     3841 gcagaaaccc ggaaatgtga caggcgccgg caatccgggg cgcctacccg acagatatgc
     3901 cggccttctt gagcaggtaa taggcaccag caaggcagat gacgacaact cccattcccc
     3961 agagggtcag atccgagagg ggaacttcac catagggatc gaggagaatg atctttcgtg
     4021 cgactgcaat gatggcaagg agaacgatga tctccacgtg aatctcctgt ttcctgatgt
     4081 aggcctttat cgtatcgagt aattcgatgc cgatcagcac gaggaggaaa aagccaaaaa
     4141 tggagagtat ttcgtggtta tcgagccggt acgtcgtatc gaggacgata cccctgaata
     4201 tctcgaagac cagttcggca acggaaaaga gaatgacgaa tgcaaggaga acgacaagga
     4261 tataatagat ccctttttca aaccggacga gattatcgaa catgtcctgc ctgctcctcc
     4321 cggccttctc ctgttggaag ggctttcttt ttcaaaaata cccggaagac cggggctgtc
     4381 ccaatcatta ttcatcttcc ctgctaaaaa acctccggac ggatcgatcg cgcatcaaaa
     4441 aacaaaaaaa gaaccactgg atatttgtag gggaagggaa aagagaactt cttatatgca
     4501 ggtctggtcc gctcttttag gaggagtatt cattgcagca ttcatcgtgg gtattgcagc
     4561 ttcctcccct cagcctggtg accagccagg atatctgcga atagaatcaa gaccaccggg
     4621 tgccatggtt atctacgacg ggatgctcat cgggatgacc cccatcacgt accctgttta
     4681 tccttccgat tcgggtcctc acaccattgt tgtctctgca accggttacc attcttacac
     4741 gacgtcctac gtgccaaagg tatctgccgg aaagaccgat tatatctctg cagaactcac
     4801 gccaacaggt tcgctcggga ccctcgttgt gaagtcccgg ccaacggggg cactggtcat
     4861 ggtggacatg gggaaaggac agcaggcacc ctggacatac caggatatca gggctggagg
     4921 acacctcgtt caggcatacc tgtccgggta ccagcccttt gcaacgatcg tagacatccc
     4981 tgacggaggg acaatcacgg tcgatgctct cctccagccc ctctccgaga cggggatcat
     5041 ccaggcgagg agttctcccg ggggagcaga tgtctatgtt gacgggatat acaggggatc
     5101 gacagccaca acgatcggga acgttgccgc cgggacgcat tttgtcctcc tgaaagccgt
     5161 tggttaccag gactggacgg gcctcgtgga ggtgaggaca aaccagatca cgccgcttga
     5221 tattaccctt acccggtata ctgctcccga gagcgggttt atctatgtca attccgatcc
     5281 cgccggtgca tctgtctacc tggacggggt tttccagggg atcactcagg caggaaatcc
     5341 cctcgacatg accggcatcc tccccggcga gcataccctg actctgacgc tggataacca
     5401 cgaggagtat atcacgcggg tcatggtgaa agcaggagag acaacgcagg tcaatgcagt
     5461 actcacccct tcccaatcaa tcgcagcatc tggaatcctc caggtcattt cggatccggg
     5521 aggtgcaaat gtcttcatcg atgatacctg cagggggatt acgcccctga ctctctcgtc
     5581 agttcccgcc ggttcccata ccctccgact cacccttccc ggctacaggg accataccct
     5641 cacctataac cagaccccgg gaggaacgtc ccatatcgag gtcgtgctca ccccggaatt
     5701 accaaaggtg gcactaccgg gacttctccc cctcattgca cttctttccc tgggattcta
     5761 tgcaacgtgg agaaaaggtt actgatactt tccaaaacct cagcatttct ttttgaaaaa
     5821 aaaggacacg ggcacggtgt taatgcccgc cctccaccca gcgggcacct tcgcgggtat
     5881 attccttttt ccagacggga acgtgttcct tgatcctgtc gatgatgtat tcacaggcaa
     5941 gaaatccggc tttcctgtgg gatgcaccga caacgatgag aacgatggaa tctcccactg
     6001 aaaggtgccc gactctgtgg atgatgtcaa cgtggacgac cccgaacttt gcttctgcct
     6061 cgcgggcaat ggcctggaga tcttgttcgg ctacctcttc gaacgcttcc acgtccattc
     6121 gctctatccc gtcgtccctg acgattccaa ggaaactgac aactgcacca acgtttctct
     6181 gccgggcccc ctcgatgatc tctcccggat cgaagtcatc ccgtgtgacc ttaatcatcc
     6241 tgcatcccct cccgggttat cctcctgcta ccgggggata caatgcgatt tcgtcacctg
     6301 gatgtaccgg ataatcttcc cgcccgttcc ccggaatcct ctccctgttc acgaggacaa
     6361 taaccgattt ccggaggttt ccttccccgt caagtatctc atgggcccca tcgggattca
     6421 tccgggcaat ctcctgcacg actgaccgga cagttgcagg gactttgacc cttacttcga
     6481 gggcgtctcc gaacaactcg cggaaccggg cgaatgcccg gacatgcact gtatcaacca
     6541 ttatttctcc aactcccgca cccgggacat tccgggtcac gactgatgca tattttctcc
     6601 cagcaaccag cctttccatc ccagaccatg agcgcatccc ttgcgatggg ctcatcccca
     6661 agaaggatcc ggagggtttc cccggcctgc atgcacccca taattccggc agtaacacca
     6721 atcaccggtg gcgacgtggt tatttccggc ggatggggga ctgcgcaccg gagacatgcc
     6781 gaacgcccgg gaagaaccgt cagcagctgg ccgaagtacc cggtcactgc agcatggaca
     6841 agggggatat ccttctccag ggcaatttta ttgaggagat agcgggcagg gtagttatcg
     6901 agggcatcga caatgatatc aacgccatct gcaacagtgg atccattatc cccggacagg
     6961 gaaacctcca ttggttcgat cacgatgtca gggttgagag ttccgacctt ttctgcagca
     7021 actcctgcct ttgatttccc tatgtccccc tcaccataga gtacctggcg attgaggtta
     7081 ctcctgctca cgatatcaca atcgacgatg cggatgtacc ctgtccctgc tgcggcaagg
     7141 tacagggata cggggcagcc aagacccccc gcacctacga tgcataccga tgcatcgagg
     7201 aggcgttttt gaccctcttc cccgaccagg ggtaactggc gcaggtatcg ttccctgtcc
     7261 cggtcagaca gtcccttctg tctcctctgc atctggatac cttacccgga agactgatct
     7321 ccttttatat ccatggtact atcattgctc gaaaaacata atagtgcgca aaaggggtgg
     7381 atggtttccc ggcgggatcc acggcgtgtt gcccaggaaa ggaacgcagg tgattcatcc
     7441 aggacaaaaa acagggatga tttcatccat ggctgaaaaa gggtgcagaa acaacagtat
     7501 tctcctggaa cgactgaaag accggctgcg ggtttatgac cggctgctca tctcctattc
     7561 cggcggcgtt gacagctcgt tccttacctt cgtggcaaaa gactgtgtcc cgggaggcgt
     7621 tgtctgtgtc ctcctcgatt ctcccctcat tccccgttgg atcgtcaaag aggcaaaaga
     7681 gagggcgtcc caatggaatg tcccgcttga aattgtctcg ttcccgattc tcgaagaaag
     7741 tgcgttctgt atcaatggaa aggatcggtg ttacatctgc aaaaagaaag gcgccggcat
     7801 ccttcgcgat attgcatgca ggatggggat aaagaccatt gcggatggcg tgaacagcac
     7861 cgatcttcgc gagttccggc cgggggtccg ggccatggac gaggcaggaa tcgtccatcc
     7921 ccttgctgcg tgcgggtttg aaaaagacga tatacgggtt ctctcccgga tgctcggcct
     7981 cccattcttc caccagccct ccttcccgtg cctcgcaaca cgcataccct atggcacggg
     8041 tatagcccgc gatgtactcc aggtgatcga gcaggcagaa acatttcttc agtctcttgg
     8101 actttcagtc ctcagggtga ggctccacgg cgcatgcgcg cggattgagg ttcctccccg
     8161 tgatatgcac ctggttctgc agtccggaaa cgagattagc aaaaagtttc gcgagttggg
     8221 aatacctcat gccagcctcg atcttgtggg ttacaggagt ggaagcatgg atgaaaacgg
     8281 gcacaaacat taggaaatcc tgactcgtcg atctttttgc cattctgcgc ggggtgaccg
     8341 gaaggccggg cgacagaaac aatcaaggga taggaaaagg ataatcccgg cacgggacac
     8401 aacgatggag aataaggtat cccctacgat cgatcccgga ttatcgaagg cggcgtggtt
     8461 atcctgcctc gggaggtacc acgaggccat ccgtatcttt tcatctcccc ttcccggcgt
     8521 catcccgact gcagaatacc atgcggcatg ggcgttttcc ctcaacaggg agggcctctt
     8581 tgacgaggcg ctcaaacact gcggggaggc actgaacctc gatataaggt gtatcgatgc
     8641 atggtttgtc aggggactga cgctttccta ccttgcccgt ttcagggaag cggttgaatg
     8701 cctcgaaaag gtcgtcgcaa ccgaccccgg gcatgccgaa gcctggtata tcaggggcaa
     8761 ctgcctgtac tcgcagggtg attacacagg ggctgttgaa tcctacgaca gggtccttgc
     8821 aatcgagccg cggtacccca aggccctgta caaccgcggt gtcgcactcg cagacatggg
     8881 tgattacgaa tccgctctcg cctcctacga tgcatgcatc gcgatcaacc cgggcgtcgg
     8941 ggttgtgcat acgaacaggg gagtcgccct tgcgggtctc cagcggtacg aggaggccct
     9001 cgatgccttt gaccttgccc tttccctcaa cccggaggat gtcagcgccc tcaacaacaa
     9061 ggcgatctgc ctctcccggc tgggaaggga caacgaggcg atggacgtga tggaacaggc
     9121 aaggaagctg tcacgcctcc cccatgtccg gcggggtgtc ctgtaaatga aatatccccg
     9181 gttcaatccc gccggcccgg tcaatggaca gaagggaggt gcataaactt ataaaaaccc
     9241 cccggttacc atatcctttt gtgtgaatgt tctgcctgcc agcctcgaga taccgagggt
     9301 cacctgtgca ctctttgggg ccataaaggc tgttgcaacg ctcaaaagga cggttgtcct
     9361 cgtccatgga ccgcggggct gcgtctacca tatcaattac atcctcggca tgaggggaga
     9421 ccgccacaac cccgtctttt caacgtgcat ggacgagcat gacgttgtct tcggggccga
     9481 ggaccggtta cggaatgcca tcgaagaact ggatcgtctc aaaagaccgg acatgatagt
     9541 ggttctctcc tgctgtgcgt cggggattat cggcgaagac ctcgagagtg catgcagggc
     9601 agcacggacg gatgcactgg tcatccccat cgaggccggg gggttttccg gcgacttctc
     9661 gacagggtat gcaacgactc tccgcgccct ggtagcccgg actgcaaaga gaggcgtgga
     9721 gaaagagagg ggaacggtta acctggtcgg aatgctccgg ggcgggcctg atctccggga
     9781 aatgaagcac ctgctgtctc tcatcggcat atccgtcgga acagtcatac cggccggggc
     9841 cacggttgcg gacctgcaga atgcagggcg tgctgaaaga aacatcgtca tatgcgagac
     9901 ttccggtctc gaggcagcga agttcctcga ggaaaccttc gggacgccct ggattaccgt
     9961 gccgtttcct gttggtgctg aactctcgct cgagtttctg cgcgacgtgt ccgtgtccct
    10021 cggcctcccg gtaccggaca gccggatcat cgcacgggaa cacttttcgt tttcaggcag
    10081 gaaacccgca attgccctct tcgccgggcc gacccgcgca attgctcttg ccaggtttct
    10141 ccgctctcat ggtctttctc cccggaccat cattctcgat tttccctcac ccctccttga
    10201 acggatcagg gaagccgcgg gcccggaatg caaaatcctt gttgctcccg gatgggagac
    10261 gattgaagag accctcgtct cccttgacat tgacctcatc atcgggggac tcatggagcg
    10321 atcccttgca acgcgtctgg gcatctccct gatcgacgtc atgcacggga gccagaagac
    10381 tgccggcgcc gggggagggg ataatattct ctcgctgatt ggaaaatgca aaaagtgatg
    10441 atgttttttt gcccgggttt aaacggtact tttccacccg gtgatacgtg ccatcccgtt
    10501 ccggaaaaag gatttactta tggatgcctt ttccgggcat gggaaagttg atgcgggcaa
    10561 tgcactcatc tgcttcttta atcctgccca ttgcacggag cgtaagggac ttctggtaat
    10621 acacgaacgc gttgactgcg ttcaattcaa gtgcgcggtc gaagcactcc agtgattctt
    10681 ccagtctccc gatctcccgg agtgcaatac ccttgctcgc aaggacgcgg atattgcgcg
    10741 ggctgatcga aagggaatga tcaaaacagg tgatggcctc gctgtatctc cccagttcat
    10801 tgagacagta tcctttgtcg ttaagggcat agagaaaatc ggggttgagg gagagagcca
    10861 cgtcaaggct tttcaatgcc tcctcgcatc ggtgaatctt tcgcagggta tacccttttt
    10921 tgtagagaac gaggagattg tgggggtcct cggcaagcgc agcatcgtac atggacaggg
    10981 cctcggcgtg cctcccgagc tcgtaataga tgtctcccat ctcttccatt gctgacctgt
    11041 tgcggggatt gcatgcgagg gcttccctgt atgcagcaag agcctcctcg agctttccca
    11101 tgttcttcgc cctctgtgcc ttctcgatcc agtccttttc ttccatccta ttgaccatat
    11161 gaatacgggt atttaaggta ttgtgcccgg taccggacgc acccggaata gaaccaatct
    11221 cctcctgtac gggattctca cgcccgcatg cagataaccg gggttacccc gatacgaggg
    11281 tgatgaaagg ggataggatc agacggaacc tccccccttt cccgatcaga caaaccttca
    11341 ctctgcagga atctcctttc cttccggaag tattgttttt aagaaagcaa tcccgatagc
    11401 cccctggctc acaactgcct ggatggcacg gtcaaggtct ttgactgaaa agtcgtggta
    11461 aaacgggtat atgtaacgcg agattgtgaa accaatgacc ctgcctccct cgatgattcg
    11521 tgagaatcct gtaaggggcg acgtaaaagc ccgtgtcagc tcgtaaatga attgtgcatc
    11581 cttcttttca tagtaactgt tcagggcgtc cacttcgggg cccgcaggaa gcgtgatctg
    11641 gaatgccacg atgtaatagc tcttcttctt ctggttttca aggagaatgg ggaagtctcc
    11701 aaaccgtacc cagaaaccgt tgaactcacc ctcgtcaaat tccctgagta tcgtcacgtc
    11761 tatctcctgg agatactggc gaagctcgtc cctgaccaaa gattcgtcct tcctcgcaac
    11821 cggtccggcc atacgtgtcc agttacgacc taaactgttg taatcctttt gccgcggggg
    11881 cagtgtatcg atggtacagg ctgatgtata tgacttcgcg gttcaatgac tatttatacc
    11941 caatgtccgt atctgttcgt ggcggcgaca ggatctcacg ggatactgtg cgacgcccgg
    12001 gatttggcat gtgtcccacg gacgtgggac atgtgaaagg aacagatccc gaacaagcag
    12061 atgtaggagg tgaaaagata gtggatgaga ggttctggaa actcctgctc ccggggattg
    12121 tcctcgcagg catgatcctc atgacgtcag caggtgcaga ccagaaccag aatatggggg
    12181 aaaacctcat gtccagttca tatcatgtat tccccgtttc ccccgatatc cccacgacat
    12241 caggcattga cactcctctc tcaaccgaat gggagagtta taccccgccg ggcacgacag
    12301 acctgactcc atacgagtca ctctccactc gatctgccag ggggacggtc tctgcatggg
    12361 caaagcaggg ctcctccgga ggcagcacgg gaggcagggt gaccatcata gaattcaaac
    12421 agatggtgac tgcgagcgga aacatacaga aattcatgtt ttcggctagc gctgtcctct
    12481 gacacaggag gccccttttt ttcagagggg gcccctgata tatttttttt catcctgaga
    12541 agtccccgat ctttttctgg tgtgtatccc gtgtgacaag ggatgagagc cgcacacctg
    12601 ccagcctgac cttctggtcg tggagaaggg gcagtccgag cccgattact gccctcctta
    12661 tgtggcggac ttcgcgggtg ggacggggaa gtgtctgtgc ccgtgtcagc gtggtgaaat
    12721 ccgggtacct taccttgaca gtaatcgtcc gtgcataagc atcctcgctc tcaagttccc
    12781 tgcatagttc atcggagagc tcgaggagta ttctggttac ctcttccggg tcaccgcagt
    12841 cgggagagaa cgtctgttcg cggcttatcg attgtatcct tcggctctcc ctcacttcgt
    12901 catcgtcgat tccccgcgcg atgtccctga ctgtgacagc cgatttccca aagagttccc
    12961 tcaggtcctg gatatccgct tccgcgaggt ccccgatcgt ccttatatcc aggttcacga
    13021 gtgccgctgc cgtttttgga ccgataccgg ggattttccc gacgggcagg ggcgagagga
    13081 attccctgat ctttccggga gtgatgacca cgagtccccc gggtttttcc aggtctgatg
    13141 caatcttggc aatactcttc ccgggcgcaa taccgatgga acacgtgaga cgctcggccc
    13201 tgtaaatgtc ctcctttatc cgttttgcaa gctcggttgc tgcagcatag tcaccgcagg
    13261 acgaaacgtc caggaatgcc tcgtcgatgc tcacctgctg gaaccggtcc gcataccctt
    13321 ccaggatgtc catgaccctt tcggatgtct cctggtagag gtcgtggcgc ggcggaagaa
    13381 agatggcatg ggggcacagt gtgtgcgccc tagtgacagg cattgccgag cggactccga
    13441 atttccgtgc ctcgtaggaa caggtcagta ctacccccct tccgccactc actgccggat
    13501 cgggaccaat gatgacaggt tttcctgcca ggtcagggta gtgccggact tccacggatg
    13561 cataaaaact gtccatgtcc acgtggatga tgatgcgggg ggaggctttc ctgcccggca
    13621 tcggaccagg accgtcatga tccagtatca ttcctggtta tccatatctg gattcgagga
    13681 taaaaacgca tagacgttgc aggggggaca gggaggtgcg gcctgttacc ggcatcacag
    13741 gactaatccg atattcttct atgccttcgg atgccattga gagatatatg actccaagcc
    13801 cgcagacaag tctccaggtt ctcgatacgc tggacacgtt tgcaaagtac ctgggcagga
    13861 gcgacgtccc tgcagccctt gccctccttg acagaaacgc atcgttcgtc agcccggacg
    13921 aagaggctgt tttccggggc atgaccggga taggtgaata cctggaacgg gaaaaagaac
    13981 ggtaccggaa tttcaggctc atgaacctcg aagcaggagc agtagggaca gtcgcgtggg
    14041 tgaacggtta cttttctgcc ggacctgact cgtcgggaaa aagttaccgg ggacgggtat
    14101 catgcgtcct caaaggcaca ggccacgcat gggtgatagt ccacgtccat ctctcctgcg
    14161 tcccggattc atgcccgcca taaaatggca gaccgaagtt gccggggaat gcagggggaa
    14221 ggggaccttt ttcctttttt gaaactacaa tgacgggaac tgctgggtca cgcagtgaat
    14281 cgctcccatc ccggtgatca tggcggaaca gtcgataccg acaacaaccc tgccggggaa
    14341 gagtgattcg agtatctgca gggctttcct gtcggcagga tcgttgaacg tcggcaccat
    14401 cacaacgcca tttccgatgt aaaaattggt gtaactggca gggaggacct cttccccggt
    14461 cgcaggcatg gggagcggga tgatggaaag agcccttccg tcatgcgacg tcgccttctt
    14521 caatagtgca aggttttcct gcaaaattcc atagttcccg gagtggggat cctcctccac
    14581 tgcacagaca acggtgccgg gactggtgaa ccgggcaaca tcatcaatgt gcccgtcggt
    14641 gtcatctcct gcgattccac ccttcagcca gatgactcgt gacacgccca ggtagtcccg
    14701 gagtttcgcc tcgatctctc ccttcgtaag ggctgggttc ctgttttcat ggaggaggca
    14761 ctgttctgta acgaggagcg tcccattccc gtccgtctcg atagaacccc cttcgagaac
    14821 catgcccgga acgaatgacg ggatttggag ttccttttcg atgaatgccg gtatccggtc
    14881 atccgatacg agttcgggat atttttcccc ccatgcattg aaggtccagt tgaccattgc
    14941 gagagaggga tcgcgtccat ggacgagaaa tgtcgggccg taatcgcgga accatacatc
    15001 agcataggga aagatgaaga accggacata tccccccggg atacattcgc gtgcgaggat
    15061 atcccggaca cgtctctcca tctccgtatc ctggacgagg aggtagatcc tctcccttcc
    15121 cacgagggcc cgaatcatcc ggatatacgc tctttccact gctttgaggt cggaaaaggt
    15181 tccattgtcg agcggccatg aaagccagac gccctggtgc ggttcccatt ccgcaggcat
    15241 cctgaacccg gcctgagccg gggtgatccg gaggtgcata tcctgcagac tgacgaggcc
    15301 atggtacgtg tcggggcgcc ggtttgcaag gaaaccccaa ccctccctga cgcaggtgtt
    15361 catcgagaga tccacatctg ccacgaggac ttcctgcccg gttcctgccc gcgccagaac
    15421 gtttccaaac gagtcacaga tgaaagaacc cccgaagaaa cagagatcgc cttcgcgtcc
    15481 cacccggttc acggctgcga tgtgcacacc gtttccgatg gcatggcccc tctggatact
    15541 ctcccacgct cccttccagt caccctcgag gggatcttcc attccccgta tcgtgccgag
    15601 tgcggtggga tagaagatga tatctgcacc tttgagtgta acgagtcgcg cagcctccgg
    15661 aaaccactgg tcataacata tgagaacggc gattcggcca aaaggagtct cctcgacaac
    15721 gtacctggac ccgggcgaga aatactcctt ctcgtaatag aggggatcat tggggatgtg
    15781 tatcttccgg taaacccggc ctgtcttccc gtccggcctg acaatgactg cagaattgta
    15841 aagctctcct ccctctcctg cttcgagcag tggaacgatg ataaatgccc cgtatgtgcg
    15901 tgcaagacgc gagatggtat ccgtgatcgg cccggggata gcctgggcat actggtttgc
    15961 ctggaaaccg tggtactggg ggaaataagg aaaacagaaa agctcctgga ggcagacgat
    16021 gtgtgcaccc tgcgcgagtg cttcctctac catgctggta ttcctttcca gatttgcagc
    16081 aatatctgtg cttgcaggtg cctgcacaag accgatccgg accatcgtgt cttcctccct
    16141 tctatattgg ttttttcccg cttatgcatt gctgcggggt ccatgccgtc caaaaccgtc
    16201 aggaaaaaca attccagtgc ggggcaagca gttttcgcag ttctccggca gtctggcaca
    16261 ccctctcgtg ggcggacgga tcggttgccc ggagaaggat ttcctgataa ccggcaggtt
    16321 cacggatgct ctccagtggg aggccggcga gggctgcgat gatacccagg ttcgtatagg
    16381 gcagcccgcc ttccacgctg taacccccct cgagaaccgc gaccagtttt ccgttacaga
    16441 tactgtctgc gagcatgact gccttcctga cgagttctgc ataaccccgg gcagataccg
    16501 caaggcctgt aaggggatcg gtgaaatgca cgtcctgccc tgccgagatt gcgatgatat
    16561 cgggggaaaa ttccctggcc agcggtgcaa tcacggtatc gaagaggtaa tggtaactca
    16621 catccccggt acccggcggg accggcatgt tgacggtata tccgagtccc ggtccctccc
    16681 ccgtctcgtc gatatctccc gaacccgggt acaggggttt ctggtgtatc gatgtgaaaa
    16741 ggacagaagg atctgcgtag aagatcgact gtgtcccgtc gccgtggtga gcatcccagt
    16801 caaggacgag gaccttgcgg acaccttcgt gctggaggtg ccggaccatg attgccatgt
    16861 tgtttaaata gcagaatccc gcgcctgtcc cggcacgggc atgatggccc ggtggcctga
    16921 cgagggcaaa ggcattggta aaatcacctt tccagaccga gatgcccgcg tggagagcgc
    16981 cgcctgctgc aaggagtgca caatcaagca ggcctcttgg aaccaccgtg tcgaagtcga
    17041 tgaatccccc cctcctgctc gcctcctcga gaaacctgac gtactcggga tgatgcaccc
    17101 tttcgacctg ctcccgcgtt gccctcggtg gacgggagac cctgatccgg ggatgatgga
    17161 acaatccctc ctcctcgatc tgatcgatgg tgtaggaaag cctctccctc ctctcggggt
    17221 gcgaaggtga ctgctcgtgc aggaggaatt cacgatcgaa gatgagcccg gttgtcatcg
    17281 tgcctccgct gttattccgg gagccacctg gacgacgata tcggcgatgc gggaagtgcg
    17341 gaaagacccg cggacgacgt caaaggaact gcagtggagg accctgatgt catcgaggtc
    17401 acggggatcg gccccggccg cgagggctcg gcgtttcact tccgcagtgc agatggcaac
    17461 gagttcatca tcgtctccca ccctgtcgat ctttcccgtc tccccgttca tgacaaccct
    17521 gccccttcct ccgtcgaagt gggcaaaaag ggtgaggctg acacgtgaga ctgcaacacc
    17581 aactgcgttg gcgcaggcag catggggggg aatgacgaag ggtttcctgg cacgccgtgc
    17641 gatctccggg acgaggatgg gggcaaggta gccgcatccg gcgatcttcg gcggatcgtg
    17701 ggctgcaacc gctgccgcga caatgctgca gtaatcatcc acggcttttt ccgcatgttc
    17761 caaccggagg ctcaaagagg ccctgaaatc accgatctcg taccctgccc tgttgagtgc
    17821 gtccgtgagt gtcgggagcc tccccccgaa ggcgagggcg tttccgtccc ttttcggctc
    17881 gatggagtcc gcgatgacag aatccccgcc aaatggcagg gactcggctt ttaccacccg
    17941 cgtgacagtc ctctcccctc cgtacacgag ttcttcggtg cagggtattc ccttttccaa
    18001 tggaacgagg tccgttgtcg ttcccccgat gtccacggca aggcagtcct ttaaccctgt
    18061 caggtaatgg acgccgaggg caacggctgc agggctcgaa ttgtaaagga cggatgggtc
    18121 tttgaggaca ttttcaggcg tcgtgagacc gccgtccccc ctgaagaaga gaaagtcctt
    18181 cttcctttgc ccgatcaggg atacgagccg gaaggcctct tccctgatcc gggcattcag
    18241 ccgcgttgtc acaatccggg ccggaaaatc caggacggcg aggggatgac tcagtgcgat
    18301 acgctccttt ggaaaatacc tgcaagcaca ctctgccgca gccatttcga gggcaggatt
    18361 cctgacggag aatttacctg caatagccac ggcatctgcg gggtttgccc gcaggaagcg
    18421 atcgatctca tccctgtcga tatcttcgac gatgtccccg cagtgattga cagccccttt
    18481 cattccactt tcgtaaaaga gacccatgcc gggtatcagg atggtcacaa ttttcctgtc
    18541 cctctccgcc aggagatggt tgagcggcgt ggacgtgctg actgcaagtc ttcccgggcg
    18601 ggagatacgg gagagtgccg tatcgatccc tgccgaattg gggactttta tggacgcagt
    18661 ctcaccatca acgaaggcaa cgtcagtatt cgtcccgcca acatccatcc cgatcagcat
    18721 gcgcggagta tcaccatgta catagaatgt gacctgctat tcccaagaga gtttgggagg
    18781 ggtatgccgg gccgccatac tggtgcttga taatgggaaa taatgtgagg aaaagggatt
    18841 aaatcccttc catgagatgc ctctcagggg cccctgcggg gatatcccat ttcggagagc
    18901 ctttctgcaa cttccgcgag gactgcaggg tcctctattg tcgggggaac ggaatacgtc
    18961 ttgccatctg ctatcttctt catgacaccc ctgaggatct ttccggaacg cgtctttggg
    19021 agccttctga caaccacagc ggttttgaag gacgcaatgg gcccaatccg gtcccggacc
    19081 atctggacca gttcacgggc gatgtccccg ttattacggt tcacattcgc tttcaggact
    19141 acaaaaccca cagggacctc tccttttacc tcgtcggcca ctcctgcgac agcacactcg
    19201 gcaacatcgg gatgcgatgc gatcacctcc tccatggcac ctgtcgagag gcggtgacct
    19261 gccgtattga taatgtcgtc cgttcttccc atgatccaga ggtacccgtc tttgtccctg
    19321 tatcctgcat caccggtcag gtagaaacca ggatatgtcg agaagtaggt tctcctgcac
    19381 tcctcgtcct tctgccagag ggtcgtgaag cacccgggag gcagcggcag gcggattgcg
    19441 atatttcccg ttgtccctgc cgggacttcg tttcccgctt cgtcaagaac ccggacgtca
    19501 taaccgggca tcgggagggt gcaggaaccg ggcttgacgg gaagtaacga tatcccgacg
    19561 gggtttgcac caatagccca gccggtctct gtctgccacc agtgatcgat cgcggggacg
    19621 gagaggttct cccttgccca tacaagggta tcgggatcac acctttcccc cgcaaggaaa
    19681 agggtccgga gagaagacag gtcgtacttc ctgatgtggc tgccttccgg atcctcgcgc
    19741 ctgatggcac ggagagccgt tggagcacaa aagagggcat tcaccctgtg ctgggagaca
    19801 accctccaga atgcaccggg atccggggtt ccgacagatt tgccctcgta gataattgtc
    19861 gtgcacccat aggcgagtgg tccgtacacg atgtacgaat ggccgaccac ccatcccaca
    19921 tccgatgccg cccagaagac ttcccccggt ttcataccgt agatattttc catgctccag
    19981 aggagggcga cgaggtgccc cccgttgtcc ctcacgacgc ccttgggaat gcctgttgtg
    20041 cctgatgtgt agaggatgta aagggggtcg gtcgccccga cgggtacgca ttccgcgggg
    20101 ggtgccctgt ccatgaaccc tgaccatgcc ctgtcacgcc cggggatcat gcctgcctcg
    20161 tattcgggtc tctggacaac gacacagcaa tcgatatcga cccctgcaag ctcaagagcc
    20221 tcgtcgataa gtggcttgta ggggatgatc cgtgtgacct ctatcccgca cgaagagatg
    20281 agaagaacct ttggagaggc atcgcgaatc cgggttgcaa gttccctcgg tgcaaaacca
    20341 ccgaagacca ccgagtgtat tgctcctatc cgtgcacagg cgagcatccc gataacggct
    20401 tccgggatca tcggcatgta gatgacgacc cggtccccct tacggacacc gagttcgagg
    20461 agacccccgg cacaacggga tacggcgtcg aggagttctc cataggtgaa ctttctcatt
    20521 gtccgtgtca caggactgtc atagataagg gcaacctgat ccttcctccc cgcttccacg
    20581 tggcggtcaa gggcattgta gcacgtgttg agaatccccc cggaaaacca ccggaaaaac
    20641 gggggattcg atctatcgag gacccggtcc cattggcgcc accacgtcac ctttcctgca
    20701 gcttcagccc agaattcctc cggactttcc aatgaccggg aatagacccg gtcataaaga
    20761 tccggaggaa tacccgacac cccatgccat gctatgacaa accatgccac aaggtctgcg
    20821 ttgccgcaca aaaatttttt tacgaaacct gcgacaggag agttacgccc cggataactg
    20881 atggcgtgtg acagctggat atatgcctct gcctcccgaa tcattaccgg cagatggatc
    20941 cattcctcat cctgttcctg ggaatctcac ttgctttcga ctgttttgca gtctcgctgt
    21001 cagcagggag ccgcagcccg gaaaaaagac tgcgcattgc actggttctc gggtcatgtt
    21061 ttggcgtgtt ccagggagga atgttccttg ccgggtactt ctccgcagga ttcctcgttt
    21121 atctcgtttc tgcgtttgac cactgggtcg cttttggaat tctccttgtc gtgggcctga
    21181 aaatggtata cgggggaaca ggagccggag aaggggaaaa ggtgaaagat tacttttctc
    21241 ccgggactct gctcgccctt tcccttgcaa caagcatcga tgcactcggg gtgggcctgt
    21301 cctttgccct tatcggtgac ggtatggtgg tcatggctct ggtcgcggcg gtcgtctcat
    21361 ttctcttctc ggtagccggc accttccttg ggggcaggct gtcggaacgt ttcggagaga
    21421 ggttcgagat aatcggtggc atgatactca tcgttattgg gacaaggatc cttctcgaac
    21481 atatggctct cttgtaattt ctcctccttg ttccggtttt ggatctgaag tctggtcttt
    21541 aaattgcggc ggaacaattt ccctgctatg caaagatggg acagtttccc tcttcgtctc
    21601 ccccggtccc attaaaacag gatacgttct cattacctcc ccttacccgg gaaaaacgct
    21661 ggtatagcgg acgataccgt tccttcataa cgtttatctt cctttttttg caagatagtg
    21721 agtaaataag ttccgggagg gattgtaatg accgatattt accgatccat ataccagaaa
    21781 atgaaaaaga tgggaatcct cgacgtgaaa cagtatgcag ttatcgaaaa tcctccctac
    21841 gtgccgctct gcattgacag gctctccccg gacacgtatg cactctccca gaaccctgtt
    21901 gtcgatggac tgatggttgc agacccggac atcgaggtac gtgtcgacca tggggaagag
    21961 accgcagaac cactggtctg cctttcacgc gagaccaaaa aggtcgtcta ccccgcacca
    22021 gggaaggtga accttgctgt ccgtaacgaa ttatcggcat tcctcgatcg gtggctttcc
    22081 gacctgatag cccaggggtt caaccggtac cagtaaaacg gctgctcgtg gttcatccgg
    22141 gggacgggtt caattagcag aatcaggagg gagaaccttt aaaaaatatt gtccggcatg
    22201 atacgatgac aggcggcggt ataaaggaac aggatgattc tcatcttacc cgggatggca
    22261 ttatcataaa tgatcctccc ttttttctcc cagaattcga ggacgcattc cgtttcatca
    22321 tcagcaccta cactccacca aaaagagaga tcgcgatatt tctcccctgt gccctcagga
    22381 aaccatacag cagcagcccg agtcaccgcc ttttccagag gatcatcgat tcccgggttc
    22441 tcccagatac ctaccatatc gttgtttttg gaacctgcgg tgtcgtcccc agagaactcg
    22501 agctgatgta tccctttgcg cactaccatt acatgctcgg gaaatgcacg gacaatacca
    22561 tacgcgaggc tttcctcgag atagagacct accgccttgc agcatacctg acaaaaacga
    22621 aagacatcta caggaaacgg gtggcttatt gcatcggccc cttcagggag gcgatgtgca
    22681 gggcaagccg gaaaacaggg attatgctcg acctcctcct gccatctgct tccactctcg
    22741 aaaaaaaccg cgacccggac tgccctttcc ctgaaggttc cctctccctg caggcatacc
    22801 tggatgagtt tgaaaggggt cttgccctcc tgtcaaaagg aaggtgaatc atcgcctttt
    22861 tcccctctcg ggccctttcc ctgacccgga atgattcaaa aagtttaata ataagcgctt
    22921 tccatcttat agcaggtgta ttagtgtcca actaagtcac cgactgaacg ttccaatcca
    22981 tggcagaaac cctgtccgtc ggacagggtg gatgcctcct tgtgggtcgt attttattca
    23041 aagttttcca tcatcgataa ccttggatct gtaacgaaat ttccaatcag ataacgggaa
    23101 aatagtgtcc ggaacgggtg ccccgtgagg acatttctgg aaacacacgt tcggccctgc
    23161 gatacctcgt ttttatcacc cgtacctctt tcgccgtttt gagatacggg ttcggggtat
    23221 tgcagcatca tgttccttga acatactctt acggccccga tgatgacctt tctttgtcac
    23281 tcatggcctt tttcgccgtt ctggaccatg agttcaagtc atcacggcag tatgttacct
    23341 gaacatttgt tcggccccgc agtgaatgac ttcttcgtca cccggacctt cgagccgttt
    23401 cgatccgggg actcatttca ctgtggcagg tatccccagt cagttcccca ctgaggcata
    23461 ccccatatag cttttatagt taatataatt tttgatcttg tcaccctttt attggcttta
    23521 ttatgtttat aaaggaggga agcgcgcata aagcgaatga aggcgccacc cgcaatgaat
    23581 cggggaacgg ggggtccatg cccggcgcat gtcacggaac cccctttttt ctgaaaaaaa
    23641 cctatttcag gaaaaaaccc gtctttgtct cctcaaggac acggggactt gtcggaggcg
    23701 tcatgaggct tacgatgacc atcgctgcaa tggcaacgag aaccccgaaa agactgaaat
    23761 ggacgggcag tggcatgatc ttaaaatacg tcaggccccc tgccaggcac gaagtgacga
    23821 gcccgagggc cattgcggcc agcgcacctt cccgcgttgc cctcttccag tagagcccgg
    23881 caaggagggg aaccgcgaat gtggcgaaca tgatcccgat acctgcccat atcagccaga
    23941 cgagcattgc aggcgggtca agtgccatca gcactgtcag gatggctgct gcggcaacgg
    24001 ataccctgct gacgaggatt acctgcctgt ctgtggcatc cggtttgatg agacttttaa
    24061 aaatgtccca tgaaaaatac gtcccaattg tgagcatcag gcggtccgtt gtagacatga
    24121 cggcggcaag gacgacaacg gcaaaaaccc cccatagtac aatattcggg agagcggact
    24181 ggatagcgta aatgaacacg aaatcccctg cattcttgac gggcggcagg gtaattatcc
    24241 cctcgctgac aagcaccctt cctgcaaatc caccgaactt gagaaggaac atgaccagcc
    24301 cgtagatgca gaatgcaacg agcggtgccc acttgaagaa tgaagcgttt tttacagcaa
    24361 ggacgttatt gataacgtga ggagcacacg ccagccccac catcaggaga agggagaaag
    24421 agaagatata ggcaggggta aaaagaccgg aatcgaccca gagcctgatg aaatccgggt
    24481 tctgcgcggc catgacttcg ttgatgtgca taaaaccgcc tgccttcatg atcacgagtg
    24541 gtgccatgac gaggacgccg gcaatgagga tgaggccctg gatgagggtt gtccatgtga
    24601 ctgcatacaa tccgccaatc acggtataga tggtcacgat gcatgctccg gtaatgagtg
    24661 cgatccaatg tggcagacca aaaagccaca tgagaacgat actcacggcc gtgtactgcc
    24721 cggcaaggta aatcagcgag acgattatcc cggaaacggc cgaaagagac ctcaatgcag
    24781 tctcacttcc gaagcggtgg gcgaggtagt cctgtatggt gaggtacccc cattcctgtg
    24841 ccaggccgtg tatctttacc ccaaaaaaga cgatacagaa cgcgatggag agcgggacaa
    24901 aaatctgttc ccagatggtg ggccatccgt acgagtatcc caggcccgaa acaccgagca
    24961 gcgacatccc gctgcagacg gaacctatca tcagcatggt gaagagccag aaaccgaggg
    25021 atcggcctgc aagcacgtaa tcgttcatcg tgtggatctt tttcgatgcc acgaccccga
    25081 tcccaacgag gatgaggaaa taaacgatga caattgccat atccaccggg tcgatcatgg
    25141 attcatcctc ccgtaaatga caccccagag gatgaggaga aagatgacac ccacaaccgt
    25201 gcaaccggtg actgcgaagg taaaaaggaa gccttcctgc atggatatcc ctaattttta
    25261 ggctcggaca caagataatg gattcgaaac cattcgccat gccggcgtag tcttcttcat
    25321 ccaccctcct gtcagcaccg gtaaggaccc gggacatttt ccataagact aataacaggg
    25381 tatcctctat ccctgatcac gttgcatggg ctcctgcgtc cggggctctc aaccataaag
    25441 ataccttgaa gtagttgttg cgataatgac aacatatcag agacatcgga ttccatggct
    25501 cttgaagaga taagacgtct gaaacgtaca gaagagaagg cactcgaaat cattgccggg
    25561 gccgaaaagg aagctgaaga tatcctttcg agggctgcag aatcagctga tgccctggtt
    25621 tcgcaggcaa tagcggaagc acaaagagaa ggcgatgcca ggagaagagc ctcactcgaa
    25681 cgtgcagaga aagagggaaa ggagattatc cagaaagccg tcaatgatgc agaatttctc
    25741 ctggaaatgg caaagaagag agcggataaa gcgacccgct gcatcgttga tattgtgact
    25801 ggtgaaccgt atgttctatc cggcccggat gtacagggtg acgctgggca tcgataatac
    25861 ccggcgaagt gcagggatag gggcactcca cgaaacgggg atgctcgagg tcattcccct
    25921 ccgtgaattc gatcctcccc tccaggatca cctcgaagcc ggagaacggg atcttctcgc
    25981 tgacaggtgt gcggaatacc gtgtccggct cgatcgggtt cttgaagccc tttacgagtt
    26041 cccgcccagc ccgggaaatt ttctgaaaga acttgtttcg ccccggggac acgaaaaata
    26101 cccggtcact gcagggaccc tggcagagct cctgcaagag atagatagta tactgaacac
    26161 aacggagcgg gcccttgaaa tcagggcttt gcttatggaa aaagacgaga ggctcgggga
    26221 atcgttccgt gtacgatcgg atctcgagct tctccaggtc atccccttcg atctttcggc
    26281 actgggcgaa tcccgcttcc tctcgatctc tgcagcctcc gcaggaacgg agactgcaga
    26341 agaagtcatt gcgcgcctgg cagagacctg cggcgacgag atctatgtcg attcccggga
    26401 atcgggagat gtcacggtct tcgtggttgc ctgcatttca gaagaaaaag aggctgtcga
    26461 gtccattctc cagtctccgg gcatcactcc tatccggata gaggcacggc agggcctgcc
    26521 cggggaagtg ctgaaagcaa cggatgagga gatatcacaa ctcaaagcag agcgggactc
    26581 gctgcaggag gaacttgctg cactgcgcag ggaacacgag acgcatattc tcgcgctccg
    26641 ggaagaactc ctgatccggc gtgaagaact cgacctcgtt acgcgatgcg gcgttacggg
    26701 cgaagtgacg gttatccagg gattcgtgcc ggccagtgca ctcacgcaga tcagggcagg
    26761 agtaggagag gcaacagagg aacaccattt tgtttccgtg caggaaccgg acccggaaga
    26821 ctcatcagtc cctgttcatt acgaaaaccc cccgttcctt gcaccgttcg agtacctgac
    26881 cacgatgttt gcacgtcccc gctacgatga gatcgacccg acaccgtttg ttgccccgat
    26941 attcctgatc ttcttcggtc tgatgctcgg tgacgcagga tacggaatcc tcatagccct
    27001 cgtcggttac ctgatttaca ggggtgcggg cagggtaagc acgacgatgc gtgacctgag
    27061 ttatatcctg actctctgtg gtatttccgc aatcattttt ggtgctatcc aggggggatg
    27121 gttcggcgat gttccccaga ggttctttgg catgacacct cccttcgtgc tgatagaacc
    27181 actcaaggat cccatcgcat ttttccagat ctccctcatt ctcggtatcg ttcacataaa
    27241 cctcggcctc ctgctcgcat tctaccagaa tttcaggaag aaacgataca gggcctgcat
    27301 attcgaccag ggcatctggt acattctcca gccatctgca ggcgttcttc ttgcagaatt
    27361 cttcggatgg gcaccggtac ccccgtggct ccatttcctt gcccttgcgg gagccgcact
    27421 ctccatcgcc atgatctttt atacacgcgg cccgatgggt ttcttctccc tcacggggtt
    27481 cctgggtgac tggctttcgt acgtgaggat actcgcactg gcgctcgcaa cagggggaat
    27541 tgcgatgacc gtgaatatcc ttgcccagat cgtggggaat gcgggtcctc tcctcctcgt
    27601 ccccgcaatc atcgtgttcc ttggaggcca ggcgttcaac gtggtcatcc aggccctcgg
    27661 aggtgtgata cacgcaataa ggctccagta catcgaattt tttgggaaat tttaccaggg
    27721 tggggggaaa gcgtttaccc ccttcagggt ggagagaatg tattcgagaa ggggtgatgg
    27781 acagtgacga taggacttgg gacggcactc ctcgcgatcg gtgccggaat agcagccgga
    27841 ttctctgcaa tcggggcagg gatcggagtc ggaataacgg gcgcggcatc tgcaggggtg
    27901 actgcggagc gccctgaaaa gttcggtgtt gccctcattt actctgccat accccagaca
    27961 caggcaattt acgggctcct cgtcgccatc ctcatcctcc tctcgggagg tttcctcggg
    28021 gggcttgccg gcgacatccc tgttcccata ggtctttctg ccatcggtgc ggggcttgcc
    28081 gtcgggatcg cagggctctc ctcgatcggg caggggattg cagcatcctc ggcggttgcc
    28141 atgacgagcg aacgtccgga gatgttcggg aaaggggttg tcttttccgt tatctgcgag
    28201 acgcaggcaa tctacgggct cctcgttgct gttctcatcc ttgtcttctc cggcctcctg
    28261 tccggcaatt acatcgcaac ggtcgcgagc gggcttgccg ggatcgggtg cggacttgcg
    28321 ataggtctgg ccggcatatc cgcgatcggc caggggatag ccgcatctgc aggcgtggca
    28381 gcaacaggag agcatcctga cctcttcggc aagggtgtcg tttttgccgc gatatgcgag
    28441 acgcaggcga tatacgggct tctcgtcgcc atcctcatca tgtcgttcac gggtatgttc
    28501 tccgggaatc tgatcactac gctcgcatcc ggagtcgtcg cgatcgggtg cggacttgca
    28561 agcggttttg ctggtttctc ggctataggc cagggaattg ctgctgcatc aggtatcggg
    28621 gcgactgcgg agaagccggg gctcttcgga aaaggagttg tttttgctgc aatatgcgaa
    28681 acgcaggcaa tctacggtct tctcgttgca gtacttctca tgtccttctg cggactcatt
    28741 tcaggagaca ccacgctctc ccttgccgtc gggtttgcag caatcggcgg tggccttgcc
    28801 gtcggccttg ccggcctctc ggcaatcggg cagggaatcg cagccgcatc ggggatcgcc
    28861 gcgacgagcg agaaagaaga catgttcggc aagggagtcg tattctcggc ggtatgcgaa
    28921 acacaggcga tctatggtct tctcgtcgca atcctcctca tggcattcac cggtatgatc
    28981 acgcatgatt tcgtgaccac ggtcgcaatc ggggttgcgg caatcggagc cggtatcgcc
    29041 gtcggactgg ggggactctc ggcaatcggc cagggtatca cgtgcgcatc agggatagca
    29101 gcgacggcca ggagaccgga agcgatgggc aggagcctcg tgtttgccgc gatgtccgag
    29161 acctttgcaa tctttggact cctggttgca atcctcgttc tctttggact ggggatcttc
    29221 catgtatgac cggatgcccg gggagcgtgg cagtgaatga gcgttgagaa gatcgagcag
    29281 cgcattcttt ccgatgcgaa gaccgaggca gagcgcattc ttaaaaaggc aagggaagag
    29341 gcagaccttg tgattgaaaa ggcacggaag gaagcggaaa aaaggacccg tcagatcagg
    29401 actgaagaag atgaaaagac tgcacgggca tgcacccagt tactgtcgca gtcgagaatc
    29461 gaagcaagaa aggtataccg gaatgcccgg gaaaatgcca taaacgaggt atttgcaggc
    29521 gcgaaggcgg aacttggaaa gatcagggag aatccccggt accctgacat attcttcagg
    29581 cttgcggctg aaggtatccg gaacctcggg caggacaggg tggagctcga ggtgcaccct
    29641 gccgacagac ccctcgcaga ggacttcatc aggaaatggg ggaagaatcc cggggaatgc
    29701 atcatttcga cccggactgt catgacgaat ggtggagtca tcgtgtcggg tcccggcggc
    29761 acggtgaagg tcaataacac ggtagaggcg aggctcgaga ggatggaacg ggagattgct
    29821 gcacgggtcg cacgaatcct cttttcggaa gggggtgacg cgggtggcag gtgaagacct
    29881 cgggagcatg ctggacacac tttcaaaggg tctttcactt gaccccggtc tcctgatgat
    29941 cggggcactt gcaatgctcc tcgtcatcgt gctcgtcatc gtgacctttc ttggttactt
    30001 ccgtgtactg ctcacgatag cccaatttgc ctatcccatt gcacgtgtca aggcaatagg
    30061 aaaccccttc atacggcccg aaacgctcca gcgcatgcgt gaaacgagaa acatctacga
    30121 ggcctgcacg gctgtccggg aggccggggc aggactcgac atacctgaaa atgcccggcc
    30181 ggaagatgtc gacaggatcc tcgatgcctg gtacattaac gaattcaatg cactgctcgg
    30241 aacgctcccc gacagtataa aacccttttt ccttgcctac cagggcgtcc tcgaggtgga
    30301 acagctcgta aaggccgttc ggatggtata ttccccgtgg ggaactgcag gtatctcttc
    30361 ccgcctgatc ccggtcggat gcctgacccc ggaacggtta cggaacctcg acggtgcttc
    30421 ggggattcgg gaactcgcag cgaggctctc cgggacgccg tacgaggagg ctctctcggg
    30481 aattgttccc ctggccgaac agtcatcatc gccgttcccc gtcgaaaata ccctctggag
    30541 attctcactg gagaggctga atctctcccg catccatatc gatccctcgc acctctctgc
    30601 cgtcgccggt ttcctcggga tatttacgga tgtaacaaac atccttaccc tcctccgggc
    30661 taaacggcag ggtatccctg cagacgtcgt ttccggatgg tttgttccgg gtggtgcggt
    30721 atacgaggag tggcgcctcg cacagctata cgaaaacagg ggggtaaaag agatcatcaa
    30781 ccagctcgca gggaccgatt actataccgt cctttcattt gccctttcgg atgcagagga
    30841 accggatctc tccatgctcg aaattgcact ggacaggttt ttactcgcca gggtcgtgtc
    30901 actctcccag gttcaccacc tccagggcgg acccctgatc aagtatgcca ttgcccggcg
    30961 atacgaagtc cgaaacctcc gtgtcctctt tcactcgctc tacgagggac tttcgatcac
    31021 ggacgtttca cggtttatcg tgacggaggc gtctttatca tgaggattgc cgttcttggt
    31081 gaccccagaa tggtccgcgg gtttgcactt gcagggataa aggacgtatt cgttgcgcag
    31141 gaccccccct ctgcgcggga gacactggta aaatggctcc acgatcccgc gattgggatc
    31201 attgtcatcc cagcacggtt ttggtccgga ctgcggggtg atatcaggag cgtggaggga
    31261 agcaggggag gataccctgt gatcctcgcc ctccctgata gttccggagg ggcggattac
    31321 gcaggagagg actacctgaa aatggcagga ctggagtgaa atggacatgg atggagataa
    31381 aaagtgccgg ggaacaatca tcagggtcac ggggccggtc gtcgtggccg atggcatggc
    31441 cggggcacgg atgttcgaga tcgtccgggt gggagaagag gccctcatcg gagagataat
    31501 agccctcgaa aatgacaggg caacaatcca ggtctacgag gagaccgccg gtatcaggcc
    31561 gggagagccg gtcacgggca ccgggagatc gctctctgtg gccctcggcc ccggtctcct
    31621 cggcacgatc ttcgatggca tccagcgtcc tcttgcagaa atgcaccagg tgtccggaga
    31681 ctttatcggg agggggagca gcgttcctgc tctcgacccc cggaaaccat ggacgtttac
    31741 accccgggca cgacccggtg accgcgtccg ggggggtgat gttctcggtg ttgtccccga
    31801 aagcccgtca gtccctcacc tcatcatggt tcctcctgcg ctttccggga ccgttgccac
    31861 catcgccgac gagggagaat acacgattca cgaccctgtc tgcaccatca ggtcggaggg
    31921 ggcagaggtg gaactcacca tggtccagta ctggccggtc cgggccggtc ggcccatatc
    31981 gcagaaactt gaccctgtgg acccgttact cacgggccag cgggtcattg acctcctctt
    32041 ccccatcgct atcggcggga ctgccgcgat acccggtccc ttcgggtccg ggaaaaccgt
    32101 cgtccagcac cagcttgcga aatgggccaa tgccgatatc gtcatcttcg tggggtgcgg
    32161 agagagggga aacgagatgg cagacgtact tgccgaattc ccacggctcg aagacccgcg
    32221 gaccggcctc ccgctcctca accgcatggt cctcatcgcg aacacgagca acatgccggt
    32281 tgcagcaagg gaggcctcgg tttacacggg catgacgctt gcagagtatt accgtgacat
    32341 gggttacaag gtcgcactca tggcggattc cacctcccgg tgggccgaag caatgaggga
    32401 gatatccgga aggctcgagg agatgcccgg cgaggagggt tatcctgcgt accttggctc
    32461 gcggcttgcc gatttctacg aacgtgccgg gagggtcagg accatcggaa cagaggaaag
    32521 ggaagggtcg atctctgtca tcggtgccgt ttcaccaccc ggcggggact tctccgagcc
    32581 cgtgacacag aacacgctcc ggatcgtgaa agtcttctgg gccctggact cggacctcgc
    32641 ttaccgccgg cactttcctg ccatcaactg gctctcctcg tattccctgt acacgggtat
    32701 tgtcaacagg tggtggaacg agaatgccgg tccgggctgg gaaagcatga agagcgagat
    32761 catggccatc ctccagaagg agaacgaact cgaggagatg gtcaagcttg tcgggcccga
    32821 ggttctcccg gagcgggaca ggctcacact cctcgaggcc gaggtgataa gggagagcat
    32881 cctcatgcag tatgccttcc acccggaaga cacctatacc tcccccaaaa agctctacag
    32941 gatggttgaa atggtctttt cgttttttgc cctcgcgcgg agggcggtat cttcaggagt
    33001 cctcacggag accatccgtt cccttccggt aaagtcgcgc cttgcccgga tgggaactgt
    33061 cccggaaaat gctgttgata ctgtctttcc cggcatcgaa aaccagatga gggaagagtt
    33121 tgcttccctc gggaggtcct gatatgcaga ggggggcaag ggaataccgg tcagtgaccc
    33181 acatccacgg gcccatcatg gtcgtggaca acgtctcggg cgtggcattc ggcgaagtgg
    33241 tcgagattac gctcccttca ggagaaaaga ggctcggaca ggtactcgaa tcccggacaa
    33301 accgggcaat cgtccaggtc tttggaacaa cccgtgacct tgacacggat gccacaactg
    33361 cacggttcac gggaaagacg atgcacatcg ctgtcaccga ggagatgctc gggcggatat
    33421 ttgacgggat agcccgcccc ctcgacggag gtgctccccc actcggggaa gaggaaaggg
    33481 acatccacgg atcgtccatc aacccgtatg cccgggaaca cccccgggat tccatccaga
    33541 cgggcatatc tgtcatcgac gggatgaaca cgctcgtccg cgggcagaaa ctcccgatat
    33601 tcagtggtgc aggcctgccc cacaaccttc tcgccgcaca gattacgcgc caggcgaagg
    33661 tcaggggaca gcaggaactc ttcgcggtgg tctttgccgc aatgggaata acgcacgagg
    33721 aggctgcatt cttcgtatcc gatttcacgc ggacaggtgc actcgaaagg gccgtcattt
    33781 tcctcaacct cgcagatgat cctgcaatcg agcgcatcat cacgccccgc ctggccctca
    33841 cgacggccga gttccttgca ttcgaaaaag gaatgcacgt ccttgtcatc ctcacggacc
    33901 tgaccaatta ctgcgaagcg ttgcgcgaga tctctgctgc ccgcgaggaa gtaccgggca
    33961 ggagggggta tccgggatac atgtacacgg atcttgcgag catattcgag agggccgggc
    34021 gcatcaaggg tcgcaccggt tccattaccc agataccaat cctcacgatg ccggacgatg
    34081 atatcactca ccccgttcct gatcttacgg gatatatcac cgagggacag atcgtgctct
    34141 cgcgtgacct ccatcggaaa ggcatctatc ccccgatcaa tccactcccc tgcctctccc
    34201 gcctcatgca gaccggtatc ggtcctgacc ggacacggga ggaccatgca caggtcaaca
    34261 accagctcta tgcagcctat gcgcagggca tcaagctcaa aggtctcgtt gcagtggtcg
    34321 gggaagaggg gctctcggag acggacaggg agtatatccg ttttgccgac cggttcgaac
    34381 gtgagtttat ctcccaggga cccgaggaag atcgctcgtt cgaggcaacc ctcgacaggg
    34441 cgtgggatct tctctccgtc cttcccgaag gagaactccg tcgcatcgac gagtcgttca
    34501 tcaggaaata ccatccggca tacagggggc agaaggagtg agtgtccagg gaaggagcgg
    34561 gattcgccct accaggattg aacttttgcg gttgaagaaa caggaactcc ttgcccagag
    34621 agggcatgac ctcctcgagg aaaaactcga cgcgatggtg gtcgctttct ttgattacag
    34681 ggatgcatac ctcgaacaga agaggcgggt cgacgaaacg ttccggtctg cactctctgc
    34741 actctctttt gcagagatgc tggcaggaac cgacaccgtc gatgccgtgg cggcttcctc
    34801 gcctccactc ccggacatcc ccaccggttc gcgcctcgtg atgggtgtcc gtgtcccggc
    34861 cctcccttcc gaatccttcc ccgtccacga gagtggttac gggctcctcg gtacaccggc
    34921 agcaatcgac aatgccacga agcgtttcga ggacctcacg agggaaatcc tcgtacttgc
    34981 cgagagggag gggacggtaa gaaggctgtc ccgggagatt agcaagacac gccggagggt
    35041 gaacgccctc gaaaggatac tcctgccgca gctccagtca acccggaggt acatcgagat
    35101 gcacctcgag gagagggaga gggaggacca gttccggcgt aaacgcatca agcacctcaa
    35161 gacggagtcc ccatgaaggc tgccccccac gacccgtgga tcgactcttt ccttcgccgg
    35221 cccgacgtga ggacgaaatt atccttctat ttcttctgcc tccaggttac gatctacgtc
    35281 accctcgttg cagggctgtt catcttcatg tacctcgtcc tcacccggac cggttaatgg
    35341 cagcagaagg gttccttttc tctgtgtcag ggttacggat gacgagaacc ggtctcgatg
    35401 cgacccgtgc aacttcctgg gccgtgcttc ccgggatgag tcctccgagc cagcccctcc
    35461 catgcgagct gaatgcgacc agggagacgt cctcctcctc gacacagcgc gctatctcga
    35521 gcgcggggtt tccgaccttc acgaggcacc gggcgggaat gttcttcctt gcaagggaaa
    35581 gggcatcttt ctccatctcg aggagggcct cccctttccg catggcaatc tcctcctcgt
    35641 tttccccgct atcgacaaca tggaggagaa taatctctga aatgccccgg agatttgaaa
    35701 ccatgtcaag agcttcacgg gccgggggcg aaaagtccgt ggggcagaga acccgcgata
    35761 gtatcctggg gcagaatttt tcgaatgttt ttcccctgaa tccttccacc atgcggtatt
    35821 tcattatcag gacactgcag ggactatgcc ggaggacgta tcccgacacg ctcccaagca
    35881 gtatatcgcg caggatgctc tttccccgcg ctcccaccag tatcatcgac gggtccactt
    35941 cctccgcaac ccggatgacc atctctccga cgggcccgtg ggaaaccgtg cgcatgattg
    36001 tccgtgcatt gaccccctgt gcttttaata gagtgcattc gctctggagc tgcttttttg
    36061 cctcttcctc catcatcgat atgccccagg gagcaaaccc cggcctcgat gtatcgatga
    36121 tatgcaggag gatgacttct ttcacaccgg ggaaacctgc gatacaatcg agcgtctgtt
    36181 tcgcgtgttc cgaaaaatca gtagggaaca gaatgcggga aaacatgtca ccatcacacc
    36241 atatccatac ctgtagcagt gttgcacgag ggaagatata accctgcgcg gcgatgtgca
    36301 tatacctcga tcttccagga tattcggggg aagatctaaa agtatgaagg gaagttataa
    36361 atagtcatat aacctttaga tcagcgaccc caattggagg ggccggaacc cagatcaatg
    36421 gcagcaataa acgaagaaac catagaaaaa cttaaaaacc tggcattaac ccggtgcatg
    36481 gagcgcatcg agagagccag ggctcttccc aaaccatctc cctcaccctc acttccaccc
    36541 ccgcccggcg tcacccggct cctcaagtcc cgtcacgggt tattataaag gagggaaaaa
    36601 catggaccag gaatcatcgc ttctggaggt cgtcaggaaa aaggaactcg aactcaagtc
    36661 ccgtatagag aaagccacga aagaagccga agaaacgatt gcacaggcac ggagaagggc
    36721 agaggagatc ctggaaagcg ctaggaagag aggagaggaa gaatcctcgc gcttcatggg
    36781 agaacaggaa aaagcaatgg accaggagat tcgggaaatc agggaaagtt cgctcctgga
    36841 gcggaagcaa gtctcggcac gtgcaggaga gcagatagat aaggcagtgg aactgataat
    36901 cggccgtatc gttgcaaaag gtccctaatg ctccagaaga tgaaaaatat cctggtggtc
    36961 ggtccaaaga aagactacca gcagatcgtc gatgtcctct accaggaagg aacggtacac
    37021 ctccaggaca tccccttttc actcgacgac cccgtttttt cccccatgga gacgggaaag
    37081 accgaggata tttcggccat tcttttgaaa ttacacggta ttgcccggat tctacccggg
    37141 aaagcggttg aaccagaaat agagagacgc accggggaat tgcggggaaa aacaacggat
    37201 gaactccttt cagaggcaaa ggaggttgtc cgcgtcctcg aatccaaagt ccgcgacctg
    37261 gcgacacgga aaggggatct cgaactgacc cggacgacac ttgaccggta tgcaaaagtc
    37321 atggagaaga tacagcccct cgagagcagg ttgcccatcc tggaaggctt cgaggtgagc
    37381 gtcctcctca tccagagaga ataccgggac gtccttgacc tgatccgtcc ccagctcaaa
    37441 gcaatcacga acaaccagtt cgagttcatt gctgcggacc ttgacgatac gaccaccgcg
    37501 gcaatcacgg tattcaacaa gaaatactcc caggaggtcc actcttttct tttctcccag
    37561 aacgtcaacg aggtaagggt tcccgaagaa tacgccaata tgcacctcaa tgaagccctt
    37621 tccctcatcg ataatcgaaa gcgtgatatc gcgagggaga tggaggagat tgacagtgaa
    37681 cttggcactc tggcggaaaa atggcagacg gaacttgcag tatacacccg cctcctcgaa
    37741 gaccgcctcg aagaactgcg atccctcaac atgttcgggc agtctgatca cacaatcatg
    37801 attaaggggt ggataccgaa aaagttcctg aaaaagacga gagaagcgct gagagaaaag
    37861 ttcggtgacc gcgtggtatt gaccgaagtc cgggtacctc cggaagagat ggaaaacgcg
    37921 cccacgtatt acgataatcc caggatcgtc aagcctttcg agttcttcat gaaactggta
    37981 tcacccccga agtacatcga aatcgaccca agccccctcc ttgcgctgtt ctttcccata
    38041 ttcttcggaa tcatcgtcgg tgatatcgga tacggactct gcatcctcgg atttggcctt
    38101 gcaatgaaaa agaagttcca aaaagtggag tggatgcagc aactcatgaa tatcatgatt
    38161 atttcatcat tcccgacgat cttcttcggg tttctcttcg gcgaattctt cggagacttt
    38221 ggagagcaca tcgggcttct ccaccccgtc catttccttg gaataacctg gaacagggtg
    38281 gaagccatga tccccctcct cgtgcttgcc attgcaatcg gcgtgatcca catcttcgtg
    38341 ggactctcca tcggcatact caacgcatat gcgaggcatc agaagaaaca tctctgcgag
    38401 aaggcaggga tgatgggtgt cgtgctggga atcatacttc tcatcctcac cttcgttaag
    38461 gtacttccct ccttcatgat gatcgtttca gcaatcatcc ttgtcgcatt cctcccgctt
    38521 ctcgtgtacg gtggtggaac gatgggggtg atagaagtga tgagtaccat cgggaacatc
    38581 ctctcctatg cgaggatcat ggcgataggg atggcatcgg tcatccttgc catggtagca
    38641 aatgaacttg ggggtgcgat cggtgtcctc gtcgccggga ttgtcattgc ggttctcctc
    38701 catgcactca acatcatact cgcaatgttc agcccgtcgc tccactcggt tcgacttcat
    38761 atcgtggaat tttattccaa attctatgaa gggggcggga cagagtacag gcctttcgga
    38821 agggagaaga aaacagattg aacaggaaat aatttccggt tacctcccgt gcttttttcc
    38881 ctgcatccgg gagggaacga agattccatc ccgggttata aaaagattta aatcatgttg
    38941 ttgaggtatt gattttatat atctttaaga ttatgttaca ggtgtaggag gcatttgtat
    39001 ggctggatgg gaaattccac tgggcgcagc aattgctttt gctgctggtg cgataggaac
    39061 tgcatgggcc caatcacgga tcgggtcagc gggggctgga acgatcgcgg agagacccga
    39121 gacatcgggt tcgatcatcg ttcttgaagc aatccccgaa accctggtca tcctcggttt
    39181 cgtcgtcgcg tccatgatca tcatcatggt ggagtgaggg gaaaagacag attttcctcc
    39241 acggtgcgca gggttgtcag aaaaagcgta tcctgccacg ggatggggag gcgattgaaa
    39301 cccggaggaa gaggggagac cttgaaatga catatgagga tctcatacag tcaatggagg
    39361 caggggcaga ggaaaaaatt gcagagattc gcagtaatgc agcccgccag agcgagggaa
    39421 tcattcagga tgcggaggag aaggcaaaaa caatacgcga ggaattcctg gcccgggccc
    39481 gggcgaccgt tgcggaccag agaaaccgtc ttctgtacaa gaccagactg gacgagagat
    39541 cggccgggat cgctgccaaa gaggagatcc tgaacgcggt gtactcccgg gtggccgggc
    39601 accttgggaa aatccgggag aagaacgatt accgctccct tttttcccga ctcctttccg
    39661 aatcgttgga agaaatggga gagaactccg ttgtccttca cgttgacccc cgtgacgagg
    39721 cactctgcag ggaggtcgtc tcgcagatga agggaaactt cacaatcaac cccgatatca
    39781 aaacgtgggg tggtgttgtc gtctcgtctc ccgatgatca gatccggata cacaacactc
    39841 ttgaatcgcg gctcgaaaga gccaagattc tgaccaagag ggaaatctgc cgcattctct
    39901 tcggggagtg atcatggatc tcggttacat caacgcgcgg gtcaggggaa tgcacagccg
    39961 gctgctcggg ccaaaagcct tcgatgcact gatgatacag caggatatcc cgtccctcgt
    40021 gagcgaactc gagaagacac cttacaggga cgagatacag gaagcgagcg tactctatcc
    40081 cggccttaag ggaatcgaga ctgcgctccg cctgaacctc gtgcatacct gccagaagat
    40141 cctctccctc gtcgagggga gcgatgccga acagcttgtc cggatcatcc ttgcccgctg
    40201 ggacgtccac aacatcaaga ccgtgatgag gggaaagcac ctgcacgtgt cccccgaaga
    40261 gatcgaagag tgccttattc ccgcagggtc cctcggtgaa ccgcttctcg tcgagctgat
    40321 caagcaaccc gacgtcaggg gggttgtcga ccttctcgcc acgtgggatg tccccttcgc
    40381 aagacccctc acgcagtatt ttgacgagta cgcatcagcc cgggagctct ccatcctcga
    40441 gtatgccctc gaccggttct actatgaaaa ctcgcttgca ctcctgaaag cagggaagag
    40501 cgatcacgag gtgatgagga cgctcctcat gcaggagata gactccctca acctgaaaaa
    40561 cgcaatcagg atgaacaggg acagggtcga tcctgaaacc gctgaaaaat acttcctgcc
    40621 gggaggcgaa cacatcacct ccgaaaagtt cctggcattg gtgaaagcag gcactattga
    40681 cgagatcgtg gggaacgtgg aaggcacgcc gtattacttc cttgctccgc tcattcccga
    40741 ggcaatgcgg acggggacgt tctccgttct ggaaaaagaa ctggacgagt acctgacaag
    40801 aaaggggacg ggggtcttcc ggagcgaccc cctgggcggt gcagtcgtca tcgggtacct
    40861 ctgggcaaaa cagaacgaga tcatcaatat ccgcatcatt gcacggtgca aggatgcccg
    40921 tattcctgat gcagaactcg agaaggagct gaggcatgta taaattcatg gtcgttaccg
    40981 atccggacac tgctgcaggt ttccggctgg cgggtgctga agtgatcgag gcagccgatg
    41041 cccaggaagc aagaaaaatc attccccctc tccttcacag ggatgataca gggatcattg
    41101 cggtgaacga ggatttcatc caggcacttg atgagaaact gatgaacagg atagagagga
    41161 cgtaccgtcc cattatcatc ccgataccga agagggcgcg gaccggaggg ggaccgggtt
    41221 atctcgagaa cctcctgcga agggcggtcg ggtacaacat tgtggtgagg cgatgagatg
    41281 attcagggga ctatttcgag gatttccggc ccggttgtca ttgccgaagg gatgcggggg
    41341 tccaagatgt acgacgtggt aaacgtcggg acactcgacc tccccggcga gattatccgg
    41401 ctggaaggag actgggccgt cgtccaggta tacgaggaca cgacgggctt atccattggt
    41461 gaaccggtaa agaacaccga acaacccctt tctgtggaac tggggcccgg cctcatctca
    41521 tcgatattcg acggggtcca gcggcctctc cccgaactgg caaaaaagag cggttctttc
    41581 atatcgaggg gaatttctgc gacgggactc tcgcgcgaga gggagtggga ttttgaaccg
    41641 gcaatagctg aagggacgca ggtgaaaggg ggtgaaatcc tcggttcggt cagggagttt
    41701 catttcaccc accatattct cgtccctccg ggagtcaccg gcacgattaa aaagatccgg
    41761 aaaggacggt tcagggtcac cgataccatc tgcgaactcg actccggaac tgaactgaca
    41821 atgctccaga ggtggccggt acggaaagga cgtccctacg tcaagaagct tgatccgacg
    41881 gtcccccttg tgacggggca gaggatcttc gactgccttt tcccgcttac caagggaggt
    41941 acagccatga tccccggagg gtttggaacc ggaaagaccg tatccgagca gacccttgcc
    42001 aagtgggcag atgcacaggt gatcatctac atcgggtgcg gggagagggg aaacgagatg
    42061 actgatgtac tctcggagtt ccccgaactc gtcgaccccc gcacagggct ccccctcatc
    42121 cagaggacaa tcctgattgc aaatacgtcg aacatgcctg tggcagcaag ggaagcgtcc
    42181 atctacacgg ggattaccat ggctgaatac tacagggaca tggggtacga tgttgcgctg
    42241 atggccgact cgacctcgcg gtggggcgag gcattaaggg aagtctccgg ccgcctcgag
    42301 gagatgccgg gtgaggaagg ataccccgca tacctcgcga cgaggcttgc cgccttctac
    42361 gagcgtgccg ggcgcgtcat ctgcctcggt ccggaaggcc gtaccggttc ggtcaccatc
    42421 gtgggagcgg tctctccccc gggtggcgat ttttccgagc ccatcacgca gaacaccctg
    42481 cgcattgcag gcacgttctg ggcactcgat acgaaccttg cataccggcg gcatttcccc
    42541 tcggtaaact ggattaagag ttattcgctc tacctcgaca gcgtcgagaa gtggtttacg
    42601 gagatgatgg ccgggaactg gagagaactg cgtgacaaga cgatgtacct cctgcagaaa
    42661 gaagtcgaac tccaggagat cgtccagctc gtaggcccgg acgctcttcc cgagagcgag
    42721 aaggcgatcc tcgaggtgac acgcatgata cgggaggatt ttctgcagca gagcgcctat
    42781 agcgataccg attcgttctg cccccttgac aagcagttct ggatgctcgc gaccatcatt
    42841 tcctactacg aggcagcaga ggaagccatg aaccgcgggg tttcgctcaa gcagatctct
    42901 tcgctcccgc tcagggccga gatcgcgcgg atgaaggaga ttagcgaggt agagcagatc
    42961 aggcagcttg cagacagggt gaaggcgcag atcggagcac tggaggtgga acactgatgc
    43021 ccccggtttc actcgtcgat cgggaattcc ggacggtcag ctacgtttca ggtcccctca
    43081 tattcgtcga gagaccgaag ggagtatcgt tcggggagac ggcgcggatc acgctgcccg
    43141 atggcgaggt acggaatggc caggtcctcg acgtttcgag ggagcttgcg gtggtacagg
    43201 tatttgaggg aacgagcggt gtggacaaca aggcaacctc ggtcaggttc acgggacagt
    43261 ccccctgcat cgatgtctcc ctcgacatgc tcgggcgggt cttttccggt gtcgggaggc
    43321 cccgggacgg gagaccggag atcatcccgg aggacacggt cgatatctcc gggatgccca
    43381 tcaacccgta cgcccgcgat aagccctcgg acttcatcca gaccggcatg tctgccattg
    43441 acggattaaa cacgctcgtt cggggacaga agctccccat cttctccggg tcaggtcttc
    43501 ccgcaaacaa gcttgcagcc cagatagccc ggcaggcccg ggtcctcggg agggaagaat
    43561 cctttgccgt ggtattcgtg gcaatgggta tcacgcacaa ggaggcctcc tatttcatga
    43621 acgaattcga acggacgggt gccctcgaac gcgttgtctt cttccagaac cttgccgacg
    43681 acccgacgat cgagaggatc gcgacacccc ggtgcgccct ctccgttgca gagttcctcg
    43741 cgtataccca ccacctccat gtccttgtca tcctgactga catgaccaac tactgcgagg
    43801 cgttgaggga gatatcaaca gcgcgcgagg aggtgccggg aaggaggggg tacccggggt
    43861 acatgtacac ggaccttgcc tcgatttacg agcgtgcggg aaggatcaag ggcacgacgg
    43921 gctcgattac ccagatcccg atcctcacga tgccggatga cgacatcacg catcccgtcc
    43981 ctgacctgac cgggtatatc accgaggggc agatcgtcct ttcccgtgac ctctacagga
    44041 gaggggcaga tccgcccatc gatgtcctgc cgtgcctctc gcgcctcatg aacctcggta
    44101 tcgggcctgg aaagacgcgt gaagaccacc gcaacgtggc agaccagctg tacgcatcct
    44161 acgcctacgg gagagacctg cgccgcctcg tcgccattgt cggcgaggag gctttaacag
    44221 aacttgacaa ggtctacctc tcgtttgccg atgatttcga gaagaaattt gtcacgcagg
    44281 ggagtgccaa caggagtatc gaggagacgc tgaccatcgg gtgggagctt cttgcaaaac
    44341 tgcccgagga cgaactcaag aggatcaagc tggaatacat tcggaagtac caccccaggt
    44401 acagggcggg gtgatacccg tggaacaggt caacccgacc aggatggaac tcatcaggaa
    44461 gagagcccag ataaagcttg cagagcaggg aagggacctc ctgcgggaga agatggatgc
    44521 gctcatccag gagtttttcc ggatcatggg gtccgtctcg cgttcacggg aggagctcga
    44581 gaccgttgcg gaaactgcat tcaggtccct cgtcatcgcc caggcagtgg acgacccggt
    44641 gacactccgt tccgtgtcct ttacgacgcg caagcagatt gcactcgata tcggaggcaa
    44701 gaacatcatg ggcgtccctg ttcccatcat cgaaaagaag aggttctccc ttccctcgat
    44761 cgagagggga tacagtatcc ttggcgtcag cggaagaatt gacgagacag ccgagcggtt
    44821 cgagtcggaa atagacttaa tcatcggtct tgccgagacc gagacggcac tccgccggct
    44881 gggtcacgag atccagatga accggcgcag ggtcaatgca ctcgaacagg tcctgatacc
    44941 cgaattaaaa aggcaggcga agtacatcaa gatcaccatc gaggagaggg aacgcgaaga
    45001 cctcttccgc ctgaaaaaag tgaaaaagat cctcaaccgt aagaaaaggg gacagggtag
    45061 atccccctcc ggcgggcaga tgtccaggaa aggttaattc tgcccttctt ttccacccac
    45121 cctttcgcag acatcgatca gtgtcttgag accgggttcc ctgcgtgcaa cctgcccggt
    45181 tcgcatcgtg accaggacat gacggagatg gcgatatgat ctcatttttc cacctttttt
    45241 ttggacctta cgggtgatgg gatctttccc tccacccggt acgactaacc atagaatccg
    45301 gattgaaaag agataaatca atgcattgca atcgtgccct gcaatgggca gggtggagag
    45361 gccctcgact gacctccccg ttttcctgtc acatggttgc cctgagaacg cgtgatgcct
    45421 tctcaacggc cactctctgg tcgatttcct ttgcgcggga ctccctgcct atggcgatga
    45481 gatcgaggac atcgcgcctc gacagccggg agaacgcaat tttctcccat acgtcccgct
    45541 cgatgaagac ccacgcatca cccagtgcat gcttgaggag gtcgatctcc tcctgggaga
    45601 aatccctcca ttcctcgcca aggttcttgc gtatcttttc tagggcctgc tcgatactct
    45661 tctccttctg gagggagaac agtctcctcc ctatctcggt cctggatacg tccggcatgg
    45721 tttttccccc ttcgatctgt gacgccgggg taaccggtaa tttacccacg gacggataat
    45781 agtttgcccc agatttatca cgtctccttc cggggggtat ccactctcct atcaccggat
    45841 accgcgacag accgggaaaa agacctgatc gggcagatat gagtcaaatg agaatgatta
    45901 ataatgacag aaatgcagaa ctcttcccat tcgagggtgt gtccatgctc acattgccat
    45961 tcctggtggt ctttcctgcc cttgttgccg ccctcctcct cctgatctcc cgcgattcaa
    46021 ggaggagact ggtcgtctgg gcaggagcag ccgtaaccgg cattgcctca ctctccctgc
    46081 tgttcatcac tcctgaatcg ggtccgctct tctatcccgt cgggtacgaa gtgctctcgg
    46141 aggggatgtt cgttgcggag ctggcaattg ccgtcttcct catctacctg gggataaaat
    46201 accgcaagta ccttgcaatt ttcctgatac ttttccaggc agcccttctc gtcttcttcg
    46261 agaccgggcg gggatcggtg gttcaccaca tcatgccgga tctctttatt gaccagttct
    46321 cgctgatcat ggccctcatc atagggatca tcgggagcct catctgcgtc tattcgctgg
    46381 gttacatggc tacgtaccat gaacgacatc caaatgttcc tgaccgccgg cggagtttct
    46441 tcttcctcgt ctttatcttc ctctctgcca tgttcgggct ggtcttttcc gactacctcc
    46501 cgtggatttt cttcttctgg gagataacga cgctctgttc gttcctgctg ataggctact
    46561 caaaaacgga cgagtccatc aagaacgcgt tccttgccct caacatgaac atcctcggcg
    46621 ggatcgcatt tgccggtgcg ctcctgtata tcattgcagt caaccccggc ggggatctgc
    46681 tccacctgca ttccctgatc cagtccggcc acgcgatcgc cctcgtcccg gcagtcctca
    46741 tcgggtttgc ggggatcacg aaatctgcac tgatgccttt ctccgggtgg ctcgtcggcg
    46801 ccatggtcgc accgacaccc gtctcagccc tcctccactc gagcacgatg gtcaaggccg
    46861 gggtctacat cattgtccgt ttcgcccctg tcctgaccgg gacgatggag ggactgatca
    46921 tcgggctcgt cgggggcgtg acattcctcc ttgcgtccgc catagcaata tcccagagca
    46981 atgcaaagaa ggtgctcgcg tactcgacca tcgcgaacct gggtctcatc gtagcatgtg
    47041 ccggtgtcgg gacctacaag ctcatctggg ccgcgatcct cctcatcatc ttccacgcaa
    47101 tcgcaaagtc cctcctcttc ctctgcgtcg ggaccgttga acatcggatc gggagcaggg
    47161 acatcgagga catgacaggc ctgatcgtgc gtatgccccg gatatcggtg atgatgttca
    47221 tcggcatcgc aggaatgttc ctcgccccgt tcggtatgct gatatccaag tgggcggcca
    47281 tcgaggcatt catcgacgcc cagttcgggc ttgcattcgt cgccatcctt gcatttggcg
    47341 ggtcactcac ggtcctgttc tggtcgaagt ggatgggaaa gatcatatcc atgtgtcccg
    47401 tggccgagag agttgagaac aacatcccga ccgagaaatg gatggtcctc tccattctca
    47461 ctgccctgac ggtcctcgtg tgccttatct tccccatcat ctcggcacac ctcatagagc
    47521 cgttcgtatt ggcagtgtat ggccagacaa cgaggctttc gcaggacaac atcaccatca
    47581 tggcgatgat gctcttcctg ctgatgatca tgcccttctc cctcctgctc tacaggaacg
    47641 acaagcggat cgttcctgcg tacatgggcg ggagaccggc gactgccgac ctgactttcc
    47701 agggatccct gggaatgaag cagcacgtcg gtctttgcaa ttactacttc gaggaagtat
    47761 tcggggagca gaaactcttc atggccggga gcgcgctctg cttcggcctg atcctgctcg
    47821 tcggaacgct cactgcaggg gtggcactat gatgcacatc ggaaacgcac tcctctttat
    47881 cgtgctcgca ccgctcatcg gcggcctcgt cgccgggatc gacaggaaag tcaccgcacg
    47941 gatgcagggc agggtgggac cgccactcct ccagcccttc tacgacgtgg gcaagctctt
    48001 ccagaaggaa cagatcctcg tgaccccgtc gcagaacttc tacatcaccg cctacctcgt
    48061 gttcatcgtg gtcagcggcg cactcttctt tgcaggcgga gacctcctgc tggtcatatt
    48121 tgcattcacg cttgcccaca tcttcctggt cctcggggca tactcctcgt attctcccta
    48181 cagtttcatc ggtgcagaga gagagctcat ccagatcatc gcttacgaac cgatgatcat
    48241 cctctctgcc gtcggtatgt acctcgtgac acggagtttc tacgttgccg acatcatggc
    48301 agcagagttt cccctcatct attacctgcc cggtgtcttc atcgggttcc tgatggtgct
    48361 gacaataaaa ctccggaaat cgccgttcga cctctcgacc tcgcaccacg cgcatcagga
    48421 gatcgtgaag ggagtgacaa ccgagttctc gggccccatg ctcggccggg tcgaaattgc
    48481 gcactggtac gaaaacgtct tcctcctggg tttcatctac ctcttcttcg catggaaccc
    48541 ccttgttgca atcctcgtcc ttgccatcgt ttatttcatc gagatcgtga ttgacaacac
    48601 cttctcgcgt gtcacatggc agctgaccct gaagagtgca tggatcattg cgggcctcat
    48661 ggggcttgcg aacctcggca tactgtacta cctctcgggg gtggtgccgg catgagttac
    48721 ctctcgcgtt ccccctgggt cctccattac gacgcgtcga gctgtaatgg ttgcgatatc
    48781 gaggttctcg cctgcctctc cccgctttac gatgtcgaaa ggttcgggat catcaacacg
    48841 gggaatccca agcatgcaga cgttctggtc attaccggcg ggatcaacga gcagaaccgt
    48901 gaagtcgtca ggaacatcta cgaccagatg cctgacccga aagtcgtcgt ggccgtgggt
    48961 atctgtgcat gcacgggagg cgtcttccgc gagtgctaca acgttgtcgg gggtatcgat
    49021 tgcatcattc ccgttgacgt ctatgttccg ggctgcgccg cccgcccgga gtccatcatc
    49081 gacgggatag tccgggccct cgccgttctc gaggataaaa agagaaggat ggaaaatgcg
    49141 ggtggaaagg agcaggccgg ttcgcctgca gggggggcac aatgacacag gacgaccagc
    49201 agacaacgat tatcgagccg ctgcacctcc tcggaaaagt agaggaattc aaaaagaagg
    49261 ggtgccggct cgtccagatg cactgcacga aggccggtga caccttcgag atcaactact
    49321 cgttcgacat caactacgag ttttccaata tcaggatcat caccgacgga aagaccgaga
    49381 tcccgagcat ttccggtatt tactggggcg cattcgtcta cgagaacgag atgcatgacc
    49441 tcttcggcat ccggtttgca gggatgaata tcgatttctc cgggaacctc atccggaccg
    49501 caaagaaaaa cccgtttgca gatccgtcct tcagggggga aaagccatgc cccgacgcat
    49561 agtcgtgcca ttcgggccgc agcatccggt ccttcccgag ccgattcacc ttgatctcgt
    49621 cttaaaagac gagcacgtcg aggaggcact gccctcgatc gggtacatcc accgggggct
    49681 ggaaacgctc gttaccaggc gcgaataccc cgaatacgtt tacatcgcgg aacgcacctg
    49741 cggtatctgc agtttcatcc acggtatgac gtactgccag gccgtcgaaa aactcgtgga
    49801 ctgcagcgtc ccggagcgtg ccctgttcct caggacgatc tggtccgaat actcgaggct
    49861 tcactcccac cttctctggc tcgggctctt tgccgatgcg ctcgggttcg agaacctctt
    49921 catggcatcg tggaggctcc gcgagtctgt gctcgacgtg ctcgaggaga cgaccggggg
    49981 aagggtcatc cagggaagct gcaaggtagg gggtgtccgg agggacattc ccggagagac
    50041 ccttgaacgg atgaggagcg gccttgatac catcgagagg gaggcgggag agatcgccga
    50101 tgttttcctg cgtgacgatt cgatcatctc ccgcacgcgg ggcatcggcg tcctttcccg
    50161 ggaggatgcc tatgcgctcg gtgccgtcgg gccgacggca cgtgccagcg gtgtgggaat
    50221 agacctccgg aaaacagggt atgcagcata cggcaggctc tccttttcgc ccgtggtgga
    50281 aacggcaggg gattgccatg cccggtgtat cgtgcgggtc aaggagatct tcacatccat
    50341 cgacctgatc cggcaggcaa ttgcaaaaat cccggacgga cctgttgagg agaagcccaa
    50401 aaagaaccct gaaggggatt attttgcgcg atcggagcag ccacggggag agcttgtcca
    50461 ttacgtcaag ggagacggga gcaggcacct tgtgcggtcc cgcatcagga cgcctacgct
    50521 gacaaacctc ccctcgctgg tcaggatgct caaggggtgc aaccttgcgg atgtccccgt
    50581 gatcgtgctc tcgatagatc cctgcatcgg ttgcgcggag aggtgatggg agaatggcat
    50641 tcttcgaaat ggcaaaaacg gcaattggca cggttctccg gaaacctgcg acccggcggt
    50701 atccctcggt agccccgaag agtacacccc tcacgcgggg cagagtctct atcgacccct
    50761 cgcggtgcat ttcgtgcggg atgtgcatga aaaagtgccc ttcgggtgcg atctgtgtca
    50821 ggaaggagga aaagacgtgg agcatcgaca ggctgaaatg tgtcgtctgc aattgctgcg
    50881 tcgaggtatg cccggcgcac tgcctgacga tggaaacctc ctatttcccc tgcgtgacag
    50941 agcacagcgc aatcgacgtc catgcaatca cctacgtgaa gcccgagcga ccgaagcgac
    51001 cggagaccgg agagaaagcg ggagagggaa cggcagagag ctcctgaaaa cgctccggat
    51061 tgttggattt ttttttatcc ctccctttat ccccggcata catccttccg gaaacgtcct
    51121 gcacacctgt cagccaggta aaggggttcc ggaaacctgt ggtccgtcgt gcagtgcagg
    51181 acgatggaga ctgcatcagg aagagttgtc ctgaatcccg gcgagatgat gaggggcgcc
    51241 tttccctggc atgttcggac cattgccccg acgacctctc cccccatcct gacaggtgca
    51301 gtttccccga tacgatcagg aggggtctct gcttgcatgc cggagaggag gtttccggca
    51361 acgcctatcg tcgggactcc cagcaggacc ccaaggtgcg ttgcgatccc tgcccggcgg
    51421 ggatgtgcgt atccatggcc atggaccaaa aagaggtcag ggagtgcagg aaccaggcgt
    51481 aatgccgcaa gaagggcggg aatttcccgg aatgcgaaat atccggggac atagggaaat
    51541 ctcaccttcg acgtggcagc tgcccgggtt cgcccgcgaa gggacccgta ttccaggatg
    51601 ataaagcacg cgtatgcatt gtcacctcca tacgagacgt ctgcgccccc caccgtctga
    51661 atgaccgatg tgtcgacagg ctgctgccct gacgcgaacc gtgcaacctc ttcctggagg
    51721 cggcgggctt ccatccagaa agtggggtct tgatcatatc ccatcccgga gcaatttcct
    51781 gctgttcctt tcaagtcccc caatgaattg ttttcccaaa aaaaatgtgg tgatcctgat
    51841 cgtccaccca tggccggatg cccctgtccc atgtaccttt tttagccccg gggttatagg
    51901 tacatacata atggaactcc ggaagccccc cgggacggat gacatgacaa agactgtcat
    51961 tcgcgaggag gtccccgatt acttccagga actctccgag tacctcgagg ttctctcgaa
    52021 cagccagcgg ctcaagatat taaagatgct cgagaagaaa ccgcgcgatg ttcggacaat
    52081 cgcttccgag atagagacca gctacgaaaa cacgaaaaag catctcgaca ggctgatgag
    52141 catggggctc atcaggaagg aagtcgggct cgggccgcag acttcaaagg gggtgcaccc
    52201 tgtttggaaa tactccctgg ttcccggggc aatggaagca atcatccgca acctcggctt
    52261 cttctcgaac atgcgcatcc agctctcaga ccttgacctg aaacgacgcc tcgaagatgt
    52321 caggtctgcg atcgagggag agatcaccgg aaaccagcct gtcctcatcg tccttggggg
    52381 acctgaagat ggaaaatttt tcttcatcgg agaaaagggc gcaaggatag gcagaattga
    52441 ccagactgta aaggaagacc cctccggaga cgtcgtgctg ggcagggact actcgtcggt
    52501 gagccgggta tcgcgtccgc atgcagttat tcgcagggag ggaaaaaaat ggctcataga
    52561 agacaggggc agcacgggag gaacgttcct gaacggcaac gctctccaga aaggtgtcgc
    52621 gaccgaggta tcggacggtg atgtcatcga actcgcgaaa ggacctgcag gagccagatt
    52681 gctcgttatc ctgccaatcg gggcttcctg acaattcctg acggtctccc tcccatgaat
    52741 accggtccgt ccattcctgt tgtcaccatc ctgatcctcg ctgtcctctt gattatcggt
    52801 cccgcctgtg ctgtcaagac ctacacgatt tcggcgagcg ccggtgaggg tggggtaata
    52861 tccccctcgg gtgaagtccg ggtcgaccat gggggaagcc agatattcat catcgaagca
    52921 gcaaacggat tcacgatcgg ggatgtccgg gttgacggaa aatccctcgg gcccatctcg
    52981 ttttatacgt tcaccaatgt ccgggaagac cattccatcg ctgcgagctt tctccccctg
    53041 acgggaacac tcgagatcga ctcctcgcct tcaggtgcat ctgtcttcct cgatgggaca
    53101 tacatcggga aaacgacacc gacgggcccg gcgagatttg acgggatcac tcccggcacg
    53161 cattccctcc gccttgtcct ggagggctac gaggactacg caaccgatat cctgatctcg
    53221 gagggcagca cgacgacggt ccctctcgtc acccttgtcc ctatccccac aacggcaact
    53281 acctccccga cacccactcg gactcccaca cccacaccta cccctgccac taccacaact
    53341 acctctccta ctcccactcg gactcccaca cccacacctt cgcctacacc cacacccaca
    53401 actaccgcaa ctacctcccc gacacccact cagactccca cacnnnnnnn nnnnnnnnnn
    53461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    53521 nnnnnnnnnn nnnnnnnnnn nnntctcccc tccggaccct gctcgtcctg gtcacgggtc
    53581 tccttgcaac cgttatcctc tcccgcgatg tcctctcctc atcccgggag cccctcattc
    53641 ccctcaaaaa gcgaatcatt gcccttttcg tccttggaat cccctgcgta gcccaggcaa
    53701 tggctctcca tgcaacaatc cgctccgggg gtgcaggagg agcactcttc tttgaccttg
    53761 ctgtcgtcgt cattcccgtc tccctctacc tcgttctctc cggcacgggt cttgttatcg
    53821 gagcactcct gtcgtggcct ttccggggca tgctgaaggc gcatacagtc gctggtgtcg
    53881 tcatggtatt cctctccctc ttctctcttg cccggggaga tgacccggcg cccgccataa
    53941 cgggcctgtt cctcctttca ggcctgctcg cagcgcttgg tgcaaggtgg caggagggat
    54001 tgtacccggc cggaaaaggg catggaaccc gcggagaggc agagaacagg gtagcggggg
    54061 actcaagcga tgtgacccgt gctctcccgt cccgcgggca gggtatgctc cccccggatc
    54121 ttgccgacaa gtattcctcg atcgagttca tcggttcggg gggccttgcc catgtctacc
    54181 gggctgtcaa ttccgccaca ggccaggagg tcgccctgaa aataccctta agatctgacg
    54241 aaaccacagg gaaatcgttc atgaaggaga tcaggggatg ggagggtctc tatcacccca
    54301 atatcgtcag ggtgaacgag gccaacattc ttcccattcc ctatatcgag atggaataca
    54361 tcaggcgtac gcttgcagac gtgcctaaac ccctccccgt ccgggaagcc gcgcgaatcg
    54421 cccgcgatct ctgcaggggc ctttcccatg cacatgaacg gcaggtcatc caccgggata
    54481 tcaagccaca caacatcatg atcacggatg acgggattcc aaagatatcc gactggggga
    54541 tgagcaagat catgggtatc cctggaatgc cgaccatcac gggattctcg ctcgcgtacg
    54601 ctgcccccga acagctcgct cccgggacat tcggggagac cgacaggaga acggatatct
    54661 accagctggg ctgcgtcctt tacgaactcc tgacagggag ggtgcctttc cccggcacgg
    54721 acatggcaca ggtgacagcg gccatcctct ccgccacgcc cccgctgccc tccgaactga
    54781 atcccgctgc ccggcccctc gacactatcg tgatgcgttg ccttgcaaag aagccggaag
    54841 acaggtacca ggatgcacgt gatctcgaac gcgatctgga tcagttcctc tcaggcacat
    54901 cgccgtacga tgatttcgat attttcgagg atacctgacc gggaagttcc aaaaaatggt
    54961 ggtctcctgc ctgcctcttt tctgcaggag actttttttt catggtgagt gtgtggattt
    55021 ttcaggatct ggcatgcatt accaatgctt tccgattgct catcgggagt gatgctgatt
    55081 tggttgtgct cctctggtgg ttgggtggct gatggagatg cagcggaatg tgcaggacac
    55141 ctccgggtgc ggcaggaggc aggtatggtc cgggatggtg acaggcacgt cagggacggg
    55201 cttttgtgcc ctggacggga catggggaac atgattcctt tgccgccact tccgttccca
    55261 ttcccggtcc acccgttatc cgggttgacc ctcccggcac ctctctctca tgcctcacca
    55321 ggactcctct ctttgccagc cccttgataa aatgtgtcca tggacgggga tagggaaggc
    55381 taccggatcc gaccaccatt gaaccgagag gttaagagga caggggtcat tcatgcctcc
    55441 ggtcttaccg gataccagcc tgagacctgc ctggcttcat gcgggattgc agcgctcttc
    55501 ccgctgccct gaaagctgcc tcgatctccc tgtagttggg gatgtgcttc tcgcgaagta
    55561 cccgttcgcc tgccctcatg ctctctcctc caaggaggca tcctatggta accttcctcg
    55621 tggccttcga gaaccgcgat atctcggacc cgaggtgtac aggatcaagg agtgcagaag
    55681 gcacggcaat gatgattgcg atgtcccagt catcctggaa acgggtcata acatcaaaga
    55741 cccttgcata tctctccacg ccaccgtcgc cgatgatgtc caccgggttc tccctgctcc
    55801 acatgggagg gaggaacgag tccagttcct ccctcatctt ttcggggagg ggaacaaggt
    55861 ctatagcgta ccggtcagca aaatccgagg ccatgacggc aaaaccaccc gccgtggtga
    55921 caacgatccc gcggttcccc tccgggtacc cttcggacgc gaggagttcg gccacgtcga
    55981 atgcctcctc tatcgagtac acaggaatga tgcccgcctg cctgaatgct gcctggtaga
    56041 cctcgtaatt gcctgcaagg gaacccgtgt gggaggcagc ggccttcctc cccagccggg
    56101 aagaccctga cttgaatgca atcacgggga ctttcggcgt gatctccgcg accgtcctga
    56161 gaaattcccg acctttccgg atttcctcga tatagaggat gatggcgcgg gtaccgggat
    56221 ccttttccag tatccggaga tagtccacga aaccgaggtc cgcctggttg cccacgctga
    56281 tgatcatgga aaaccctatc tgctcgggaa cgctccagtc gacaatggtc gtgatgaccg
    56341 cgccactctg ggatatgaac cccaggggac cgttcctcgg catgaccggg tcgaacgttg
    56401 cattgagtcc aagccggggc acgattattc caaggcagtt agggccgata atccgcattc
    56461 ctgcactcct tgcaatggaa aggacctctt cttccctttt ggctccctct tcgtcgtctt
    56521 cccggaaacc cgacgagagg atgattgcga ggggtatttt tttctccccg cactcgcgga
    56581 tgacgcccgg gactgccggg gcggggacag cgacgacagc ggcatcgaca tttccgggga
    56641 tctccccgac cgtccggtat acctttttcc ccagtatctc cgtgtggcgg ggatttacag
    56701 gataaacggc gcccgaaaag gagaggaggt tccgcaggac gacatacccg atcttcgcgg
    56761 ggtccgcgga cgcaccgatg actgccactg accggggtgt gaatatcccg caatcgaccg
    56821 gcatggttga tactgcctcc cgggccgatg cagcattccc tgaaaaggca cggatatcaa
    56881 cgaccttgca tcctttccga aagagaatga ccgggttaca gtcaaactcg aggagtgtgt
    56941 cgtcacggaa gaaaacctcc gacagggaaa aaatggtatc gacaagcgcc tcctcgtcaa
    57001 ggggagggga cccccggaac ccgcggatga gcgggtatcc cctcatctcg tgaaccattt
    57061 cccggacctg gtctttcccc acgggaagca ccctcatcga gacgtcccgg agaagctcga
    57121 cgagaacccc gcccatcccg cagaggatga ctttcccaaa agtcggatct gttttcccgc
    57181 caacgatgat ttcaagacct ggaggaacct gtgcctgaac gaggacgccc tgcacgactg
    57241 ctccggggac ccgtgacggc acatcccgga gcatcttttc gcaggccctg gcggcctcct
    57301 ctgcggatcc tatccccgtg acaaccccgc caacatcggt cttgtgaaca acctggtcgg
    57361 acaggatttt cagcacgaca gggtacccga tggcatcggc agccctcgcg gcatcttccg
    57421 gtgtccgggc gatagcgtac gcgggaaatt cgatcccggc atttccaagc ctctctatga
    57481 cgtttggaaa ggcgatcatt ctccctggtc gtgtgtcctg ctggtttcct tccacctgtt
    57541 tgcctcctgg gaaaaaccaa ttcttttcgg tctgcctgtt ctttccttgg ccctgacctg
    57601 tcattacaat atcggacacg gatgcgtaca tccctgccct gcgcccctgc atgcccttta
    57661 ttgtattctg ccgccattat tcatgcatgg ataaaaaaga cgggtatcgc aggaaaaagc
    57721 gaatcccgtc cgtcccggac aaacacctgg ataccaatcc tcctttcgtc gtcggggaga
    57781 tcccgtccgc cctctccgac gcgatacggg cgtatatcga gaggaagacg gggaaagcat
    57841 ggggagatcc gactgtcctc gagcggctta tgcgggcaat cgttgcccag aaatcagcat
    57901 actggaagaa gagccaaaag aaggtctcct acaggaaagg ttaccaggtt ctcgggtacc
    57961 tcgtctacca ttttccggtc tattacgcgc aggggatgta cctcatggag gatctcgccc
    58021 ggagagggct cgtctttccc tccatgcgga ttctcgatgc ggggacagga cccggaaccc
    58081 tcccccttgc aatcgccgat ttcatggaaa gccgcgaggg gctctccgcg gaggtcttct
    58141 cgatcgaaca gtcggaggag ttcattgagg cctacacgtt cctcgcggaa cagactgcgt
    58201 cggaaaagag ttccgtgtgc ctgcacaggc ctttgcagaa agatatccgg tttcttgacc
    58261 cggacgatat tcccccgtct cttgacctga tcattttcca gaacgttctc aacgagatcc
    58321 cttcccaaaa ccctgcggag aaaggcgaac ttgtcaggaa gtttgcaccg aaactctcgg
    58381 agagggggtg tatactcctc gtcgaaccgg ccgacctcga caactcccag gaattgagga
    58441 gagtggcctc ttccgcatca ggaaaagacc tcttcatcca tgctccctgc aggttcctct
    58501 ggggccaggc ctgccgggga gaatgctgct ggagtttcga gacgagacct cccatacggc
    58561 ctcccccttt catgcaggac ctcgcgcggg gcagggaggg gttccggttc cggaacgtgg
    58621 acatcaagta ttcctattcc ctcctgcgga aaatcccccc gccccgggtt cccgggatac
    58681 ctctttcggc aaagcattat gtccgcctct ccacccttgg acgccacgtg gacaggagga
    58741 tccgggttgc cgcaaccatt gcatcagggg acctcgggga ttcggtgacc catgtctttt
    58801 tcgtgtgcga cgggagtccg ggggcgcctg cctacgccgt cctcccgcgt taccatgtca
    58861 gcgataagaa caggtggctc ctttcagccc cctacgggga tatcgccgag ttctcgccgg
    58921 tcctcgtccg ttataatccc cggtacaggg catataacct tctcgtgacg cgcaacagca
    58981 tggtgaggcc ttttactgcc ccggactcct gaagataaga gtagggagcg cagttgtgac
    59041 agtacgtgtc cgggacgatg gatagggctt tatcccttcg attgtccata ctgaaggata
    59101 ggcagggtac cggggacacg ctccgttacc cgtgtccccc acgtctgcat cgtactgcgg
    59161 gggttttggg aaaagatgcg gcatatcatc tctatccggg atctgggaaa ggaggagata
    59221 ggaagaattc tggacgaagc ggcagccatc cagtcccgct cctacgatcc ttcagcgttg
    59281 aaagggaagt tgcttgggct cctttttttc gaaccgagca cgcggacacg gatgtcgttt
    59341 gcggctgcca tggcgcgcct cgggggaaac ttcctctcca tggacagcgt ggaggcaagt
    59401 tccatggcaa aaggcgagac cctggcagat acgatcaggg tcgtgagcgg gtacgtggac
    59461 gcgatcgtgc tccgccatcc gaaagagggg gcagcgcgcc tcgcaagcga gtttgcaaca
    59521 gtgcccgtaa tcaatgccgg tgacggggcg gggcagcatc cttcccagac cctcctcgac
    59581 ctctttacaa tccggcagtc catgccgctc gaagggatcc atgtcggcct cctcggtgac
    59641 ctccggtacg ggaggaccgc tcattccctc acccatgccc tctcccttta caacgtgacg
    59701 atccatacca tcacgcccaa gggactcgaa ctcccggccg ggcttgccac cgagctccgg
    59761 gatgccggga cggaggtcat cgagcatggc gatatcgcgt cgtgcatacg tgacctcgac
    59821 gtgctgtacg tcacgcggat ccagagggaa cggttcccgg acgcagcatc ctacttcaag
    59881 gttgcctcga gttaccgggt aacacccgaa ctgctcaccg gcacgaaaaa ccacttcatc
    59941 gttctccatc ccctcccccg cctcgacgag atcgacccgc gcgtcgacga acttccctgt
    60001 gcccggtact tcgaacagtc ggcaaacggg atagcagtca ggatggcgat gctcctgcgg
    60061 gtgatgacat gacgcgggag aaggacgcgc gggcagggct cctcatcagc ccgatagaga
    60121 acgggaccgt gatcgaccac atcaccgcgg gagaagctct caacgtgctg cgcatcatcg
    60181 ggatcacggg gaccacgcac gagtcgatat cggtcgcaac gaacgtcgag agcaagaaga
    60241 tcggaacaaa ggatatcgtc aagatcaaga accgtgagct ccggaaagag gaggttgacc
    60301 gcattgccct gattgccccc aaggcatcga tcaacatcat ccggaactac aaggtctggg
    60361 acaagaaggg cgttgagatc ccggaccggg tcgtcgggat cgtccgctgc ccgaaccccg
    60421 gctgcatctc caatacaaac gagcccatcc agtcctgctt cctcgtccag aagaaaggac
    60481 tgcggtgcct ctactgtgac tggctgatca caaaggacat cacgagccac atcatgtgac
    60541 tttttttcac aaccctggcc aaaaccacat tcacggacac ttccgtgagt gaaacgcccc
    60601 attctccttt attctctgcg tgtgtgccac atgagtgcag cagctcgcgg gaatgagttg
    60661 gttcctcaaa ataaaagtaa tatcgtcttt tttaaacaaa ttggagcccg aatcactgcc
    60721 ggggtatcga ttctggaaaa caaggggtga tattttcccc attggtatgg aggggcgggc
    60781 tgcccccgca ttcttttcct gtcacccacc cgggatttcc ggaaaaaaat ttccaaaaat
    60841 caaagggaac cgtcaaatca tcatttcagg gaactgatgt cctgtgcttc aggtgaccga
    60901 tcttctcttt ccaggcccgc atctcgtccg tgatcaccgg gctgaccgcc ccgccctggc
    60961 gatcaccccg ggacgttccc atctcctcct cgagatcccc ctcgatgtca aggtagatat
    61021 cccggatggc ctggatgacg tcttcgtcgg cgtcccacat tccccgggca ttcgcttcga
    61081 ggagcctccg ggtcatctct tccaacgccc agatgttgtg ctccctgaaa aattcccggt
    61141 tttccctgtc gatgaggaaa gtccgggcga tatcgtcaaa gatgcggtca tcgacctccc
    61201 ccgtcgtcgc gtcccagcca tagacccgtc ctgccctccg ggagagttcg gcagcaccgg
    61261 agtagccatg ttcccgaagc cctgcaatgt actgcgggtt aaggagcttg gtccggacaa
    61321 ccctccggat ctcctccgca agcgtccgca cttcaacggc cgcggtattc cgggtgtctc
    61381 cataataggc cgggacttcc cttcccgata cctcgcgggc tgctgccgtt atcccgccgt
    61441 gggacccgaa gtagcagcag cacccgagca ggtcatactc gtccgtgaca accttgttga
    61501 aggtgacatc gacgttcgcg agctggcgga caaggtcctg ccttgcctct cccccgaagt
    61561 tcccccggcc ataggaatac ccgttccagt aaatgaaaat gtctccgagg tcagcagccg
    61621 tttcccatgc cgaagcgtac accgcgaggt tgacgcccgt accataggtc ccgcggggag
    61681 caccgaagat ccgcggggtc accttcccat ccgcagcttt tttccgcagg tagttgcttt
    61741 ccggcggctc atcgagcgag gcaacctttc tgatggcatc gtcgaggaat tccacgcacc
    61801 cgaagaaaca gtccctgagg atccccgaga ggcggaccgt gatatcgatc cttggtctcc
    61861 cgaggcgttc cagaggtacc acgcgaaatc cgcgcagttt cccgtgttca tactccggct
    61921 cgaccccgat caacgcgagt gcctgcgcca tctgttctcc ctcggcccac atgatgtccg
    61981 atgccatcca gaggagcgca acgttctcgg ggtacctccc gttctcattc ctgtacttgt
    62041 cgatgaggag gtctgctagc cgggacccga tcgtccaggc agcgggtgtc gggacggcag
    62101 agggatcaag ggagtaaaag ttacggcccg tcgggaggat ctcgatcttt ccacgggaga
    62161 ggaggccgga agggccgggg ggaatgaacc tcccccgtgc cccggagagg aggctcccta
    62221 tttcatcgga gaggtccagg cgacgggata cctccgagac ttcgtcccgg aggcgggaaa
    62281 gccctacgtt gtcaatgtct gcgcattttt caccgaggac cgcggctgcc acgcgggatg
    62341 gttcgtcgcc cgcaaggatt cctgccacga tatcctctgc aaaccggtca aggacaccga
    62401 gaagtgccga ttccgaggga gagatacgca tatcgagccc catcatgcgg gcgaccaggg
    62461 catggatgtg gccgtcgtgg ttgagaatgg atgcaataaa cctcgccctc cgcttttctt
    62521 tcgggatatc cccgaatatg tgcatccctt ccgggatcct tgtcgcatac attcccgaga
    62581 ggaggtggtc gaccttcgca agaaccgcat tgaaatcgcc gctcatctcc cggagatcgg
    62641 aatacccgag ttcccgggta aaaccctccc tttcgagcgt ctcgaggatc tggtgccgga
    62701 gggcatgggc cctcgcacgg tctgtatccc cgaacttccg aaacgccgcg accatctctt
    62761 ccagttcctt caggacaccg taggggctcc ccggtgccat cacggtctgg aggtgatcga
    62821 cgagcgtggc gtatgcccgc cgcttggcaa tggttccttc cgatgggttg tccgagttgt
    62881 aaatgtagag gagcgggata tccccgagca ctgcatcggg caggcactcg gcggaaaggg
    62941 caacggactt tcccggcagg aactcgagcg ttccgtgtgt cccgacgtgg ataacgacgt
    63001 cggctccaaa ttcccgggca atgtacctgt acaccgcgat gtagtgatga ggcgggggga
    63061 cgtgggggtc atggagtatc cggcagaccc ggccatcgca ccgggagccc gcacacccgc
    63121 gcttgggctg ggtaaggacg atagcgtttc ccaaccggac acccgggatg atcattctgc
    63181 cctggtagag cattgccggc gggacaccat ccttttcctg cccgggcggt tcaccccacg
    63241 ttgcgatcac ccggttccgg agatccacgg ggagttcacg gaaccattcc ctgtacgttt
    63301 cgggatcgac catcccgagt gccccgcccc gcgcgataat gtcttcgact gttgtccagc
    63361 ggaactcgtt gatggccctc cgcccgagga tgaggcgtgc cagttcttcc ccgctctccg
    63421 ggacctcgac gaggaacccc tcttccctca tccgggagag gatgcggacg acggactcga
    63481 gggagtcaag gtgcgccgcg gccccgacat ttgcctcgac tgaagcgcac gcggaactgt
    63541 tcaggatgaa tgcaactctc ttctcccggt cgggtttctc ccggagcctg atgagtgctt
    63601 tcacccgcgc aacgagggcc tcgatcctct ccgggatggg catgtgccag gcatgctccg
    63661 gtccttccgg tccctccctc atcgcgcttg ccaccggtat catcccggtc atcccgtaca
    63721 tttccgggag gatgatggcc cagccaagtt ccgtgctgcc gatcccatcc tgtttttcct
    63781 gccattcctg gcaggtcctg tagtagagga ccagggggtg gataacaggc acgccgagtt
    63841 cagtaaaggc ccggacaggt tccccggcgt catgggagag ggcagatgac gggaggcaga
    63901 tgatggcgtc cacgcctgag aagtactccc ggacgacgct ggccgcgtcg cgggatcccg
    63961 ctgttgcgtc ccccgttccg accgagaacg cagcgatgac atcgtgttcc ctttcgcact
    64021 ccctgatgag ggcattgacg gcatcgagat cgccgtttga ccagtaaatg cggtagaaga
    64081 ggataccgat ggcatggggg tgtttccttc ccctccattc ccagtactca ccggccgaag
    64141 taaagatccg gggggcgtcc gggtggtata tcccttccca gagatcaagg gccggttcct
    64201 cgaagtgcac gggctcgcgc atgatcgccg agcggaggaa ccgcaggagg tttaccatgt
    64261 tcgaggtacc gccataagaa aaataggcgt tcactttcgc ggtcacggaa aggggctggt
    64321 tcgagaggga ccagaaagac tggtcagtgc cgtacgagat gacagggacg cctgcaggga
    64381 gtgcaggaat gagcgtatcc cagtaggact cctgcgtcgg gtggaggatg atgatatcgg
    64441 attctgccag gctcgcgatg cacgacgaga gattttcagg gtcccggagc ctgaacgttg
    64501 cccatgcatt gagatcgatc ccctcgtcgg ctgcaccctc ccggagaagt ggcagttcgc
    64561 tgccccagac aatggcagag atgcgcattc taaggaccct ccctggcggg ttcgatcgcg
    64621 atgatatggg aaaacccatc ggcgcggtcc acacgcacct tcacaccgta gacgtccctg
    64681 acaagatctt cggtgaggac atcggccggc cttccttcac cccggacccg gcctcccgag
    64741 aggacgagga cacgatcgca gaaacgggac gcgaggttca ggtcatggat ggccatgatg
    64801 acgccggttt tcttttttgc tgcatgggcc ctcacgattt ccatgacctc gagctggtgg
    64861 cggaggtcaa gcgcgcttgt cggttcgtcg aggaggagaa gcaggggctc ctgcacgagg
    64921 gccctcgcga tcatcacctt ctgcctctcg cccccgctga tctgggttgc attccggaac
    64981 gcaagttgcg aaaggccaag gtcttcgaga accgcggtga ccctggcgat gtcaccttcc
    65041 ccgatccccc acgaaacatg ggggcgcctg cccatgagga ccgactcgaa tacggtcatg
    65101 gccatcccga tcgagagagc ctggggaacg tacgccatca ggcgtgccct ctccatcggg
    65161 ctcatggcag agacctcccg ttccccgaac gttacccttc cctccgggac gaggatgtgg
    65221 ttgatgcact tgatcagcgt ggtcttcccg ctcccgttcg ggccgaggat gcccaccacc
    65281 tcgccttcgt ccacggacag gctgacccga tcaaggacgc gtctcttttc gtaggtaaac
    65341 gagagatccc tcacttcgag tctcaccagt actcctccct gcggcgcatg aagagataga
    65401 ggaagaacgg gataccgatg aacgatgtca tgatcccgac gggtatgatc tggggtgcaa
    65461 gaatggtccg tcccaggctg tcggaggcaa gcaggatgag tgccccgacc agccccgaac
    65521 cgacgatgag gtaccggtgg tcgcccccga tggcaagccg cgtgatatgg ggtgacacga
    65581 ggccgatgaa accgatggtc cccgtgaaac agatgacagc cgcagtgatg agggatgcag
    65641 caaccatgtt gagcgtccgg gactgcccaa ccctgacccc gagactctgg gcgacgtggt
    65701 ctcccatgga gagagcattg agatcccacg acttccagac aaggaggggt gtgacaaccg
    65761 cgaccacgat cgagacgagg gcgagtttct cccacgacgt gcgctgcagg ctcccgaaca
    65821 tccagaatac gacggcctgg agctgttccg tcgttcctgc atactggagg aacgaggtca
    65881 tcgccccgaa gaggtacatg aggatgatgc cggcaagaac catgctctcc gacgatacac
    65941 cgcggattcg ggaaagtccg tagattgccc cggccgcaag aaggctcatg gtaaacgcac
    66001 ttatgacaac cagggtgtcc gagaagacca cggccggtat gacgatgatg gcaagagcgg
    66061 caccaaatga ggctgcagat gcgataccga gcgtgaaggg acttgcaaga gggtttctga
    66121 gcactccctg catgaccgcg cctgcaactg ccaggccaaa accggcaacg agggcaaaga
    66181 ggacccggtg gagccgcagg tcccagacga tggtatgggc catcgggtcc gaagagaagg
    66241 ttcccggtgc aataccggca aggacggctg tcatgacatc cgcggcgccg agccccgccg
    66301 acccgatgac aatcgaggca atagcgagga gaaatgcaag gacaaggagg gtaacgagga
    66361 agagaaccct gcgcacctgg gtctttcgga atgctgcggc gactgtctcc tttcctccct
    66421 ccatttttcc caccccccta gtcaacagga tagatgaaca tgtccggtcg tgcgagcgac
    66481 ggggcgaggc cctggaactc ttcgaggtac ctgcggtgga gaccctccgg gtcgaggtcc
    66541 cctgcctgct gcgggtggaa ccaccgcgcc atgtacgtca cgccgatgat gtactgcggg
    66601 ccgccgagga tcccgttgtg gaggacgtag acccgcccgt tcctgacggc aggcaggctg
    66661 ttccatcccg ggcgtgcgag gatcgcattg tatacctcgg caaaccgggt actgttctcc
    66721 cccgagtatc ccccgaagat gtacttacct gaacctgcca gcttcacaat cacgtcgggt
    66781 ttgcgggcaa cgatggactc ggggtcgact tccgggtact cggcaggact gtccgcgaag
    66841 atgtttgtac cacctgccat cgtgatcttg tcgtggtaac ccgaaccgcg tgatgcgctc
    66901 ttgaagtcgt tccatgtctc gaggtacacg aggggcgggt cccctgccgc ggccacacgt
    66961 ttcacctttc cgagggcttg ggtataaaat tccgaaagcc gttcaaagtc gtgttccctt
    67021 ccaaagatac gggcaatgtt ttgagaatcc ccaaggtagg tctccggcag gtaacagtcg
    67081 aaccggaaaa cggcggtccc gggcagggac gttttgaccc ttttttcgat ctcgtcgcac
    67141 tcggcggtgc tcaccgatgc atagaggaag atggcgtcag gctgcaggga aatgatcttt
    67201 tcgtagtcag gagcccacac ggagccaacc gaggggtacc ctgcatattc cggaaagaac
    67261 tcgggtttat gggcgttgta cttgtccacc gcgataacag actccctgcc aaccccaagg
    67321 gaacgcatcg tctcgagggt ctcgctgttc atgacgataa ttctccggag aggccgggaa
    67381 agggttacag ccctccctgt tgagtctgtc accgtccggg ctttcccgtc ccagtgaagg
    67441 tatatccagg ctgcgtcccg gagatcctgg aattcctggc cggagagtgg ttttcctgat
    67501 tccatggcgg ctataacctg cccggccagc tcatcgcgcg tgatcacacc gtccgagtca
    67561 gggtcaccgg gaagacccgc ggatacgatg gtgcacgtga tcaggatgaa ggccgctgcg
    67621 accaggagaa gcgaacgcgg tgtcatggcg aaccgttcct cccttcccgt cttttccacg
    67681 caccaaggat tgctgccatc gcggcaacaa acggtagaat gagatttaac cctgcctttt
    67741 tgacgggcga accagtgtcc ttctgctggt ccccgcctgc aggagaccct gattcacctg
    67801 gtgcagagat ccctccgctt tctcccgtcg cgatatctgc ccatgaaccc ctgattgctt
    67861 tttccgggtt ttcctgcccc ttcaagaggt aactcacgtt ccgttcaccg aggacggcga
    67921 tatagagagt gttcccgtca atgcggaact gcccgggagg aacagagata tccccgacct
    67981 cgtatcctgc cgggatggac tcggagattc ctgccaccat ctcatccggc aggtggagga
    68041 tgaccctgta cgtggtattt tccaccggga ttacagtcct ttcgacggag gcggccatcg
    68101 cctccggaac gacgaggagg gatgcgagca gggcaacaca tgcaacctga taccagcggt
    68161 tcattgcaat acacttctcc tgtaatacac taaaaaataa ttgttttatt ttgctctttt
    68221 gaattattga aatttcatta ttaatatgct tagtcgggag aatcttcata atttttcttc
    68281 tatgtgtacg accatgataa tgaagacagt acttttcccc cggaaaaacc aggttacggg
    68341 ccggtaccca cggaaatgct atctgcatgg aggaaagact ctatgacgtg acaatcatgc
    68401 ccggggcaat cattccatga ccatcatcga gacatcggga ctgacgaagt actacgggga
    68461 cctgtgcgcc gttgaccacc tcgacctgtc cgtgggaaac gagatcttcg ggctcctcgg
    68521 accgaatggt tcgggaaaga caaccactgt actcatgctc acgactctcc tcgaaccaac
    68581 cggggggtct gcccgcatct gcggttacga tacgagggaa gaggcgcggg aggttcgcag
    68641 gcagatcagc tatgttcccc aggagatggc cgtggatatc aagctcaccg gcagggagaa
    68701 cgtggctttt tttgcgaagc tgtacggtat cccccggagg gatgaagcag ttgaccgggt
    68761 cctttcgatg atggacctct ccgagagggc agatgacctc gtgcgcacct actccggcgg
    68821 gatgcgacgg agactcgagc ttgcacaggc actcgtccac gaaccaaagg tgcttttcct
    68881 cgatgaaccg accatcggcc tcgatgtcgc tgcccggcgg aagatctggg aacacatcag
    68941 gaccctgaaa tcccgcggca tgacgatctt cgtgacgacc cactacatgg acgaggctga
    69001 ccattcgtgt gaccgcgtcg cgatcctcga ccggggacgg gtgatagcgg tcgattcacc
    69061 ttctgccctc cgtgcccggg tcggcaatga catcatcagt gcccgtgtca gggggcagat
    69121 tggagatacc ttccccgaag gtatcacgca tcttggagag agagagaacg gagagattgt
    69181 cttttcaaca gaccacgggt ccgaaaaggt gccggtgctc ttccactggc tcgaaaaacg
    69241 gggagtctct gtccagtcca tatcagtgcg cgaacccacc cttgacgacg tcttcctctc
    69301 ccttgtaacg cagcgggaag agggtcatgg atttgacgac cacaagttca ggacgatgct
    69361 gcggaggaga tgatgaagga tatcctgtac tacttcgagc gggacatgct ccggtggatc
    69421 aggggccgga tttccgttat ttcggctctc atcatgcctg cagcatggct cattttcgtc
    69481 gggctcgcac tcccgaccac gttctcggag cactacatcg acttcatcac gccgggaatt
    69541 ctcgtcctga caatgctcgg cgcgtccctc cagggaggat cgctcctgat attcgacaag
    69601 atactcgggt tcctgaacaa gttcctggca ctcccctctt cccgcgagag catcctgctt
    69661 ggaaagatcc tcttcatcac gacacggggg ctcatccagg caacagtcat cctcgtcctt
    69721 gcctgggccc tcggtgcatc gctcctctca ccggcgggaa ttctcctctc ctacggtatc
    69781 cttgcgctct ttggcatcct cctctctgct ttctcgacga cgatcgccct ttacctctcc
    69841 gaccacgact cgtacgcggc tttcaatgca atggtgagca tgccgctctt cttcacgagc
    69901 agtgccctca tgccctattc cgtgatgccg tcgtggcttg cgcctatcgc atactggaac
    69961 ccggtcagct ttgctatcga tgctatccgt tccctgcagg agggtgtcct tgcatggaca
    70021 cgcatcgggg gtcttgccgt gcttgcagcc ctcgttgttg ctttctgtgt gcagaaattc
    70081 cggaaggtaa ccgtgtaaaa acggatggaa cacttatccc ctccggtgca ggaaacgggg
    70141 gaaatccgaa cactcccccg gatcggatgg gacacctgga agaaccacga ttccggggaa
    70201 aaactgacct tttatcccgt cgggaggcct gatgggatga ttcatcatta tctttgttaa
    70261 aataattttt actatttatc atatttatta tgaatataat aaaaaaattt attactacaa
    70321 agagcaatag atctctggcg gatttcagtc gcgtgatatc ctgccacagg caagaagaaa
    70381 ttcccctgca aggggaattg aatcgcctca tggttaaaag aaatgtgcgt gaatggagag
    70441 agatccatga aactggccgc agaagcaaag ggtggttcca cactcgatat caaaaaggac
    70501 gcctgtcttt tccgggccca gagggggcct ccgggaagtc cctattcccg gggaaaagac
    70561 ctctatgtac acgagagaaa gggacagact cccctttatt acctccaccg ctggtcagtg
    70621 aatgcagggg agaaggagag tattgtccca atctcaccga tcatggctgc aaggttcctg
    70681 gaggagaggg gtcttgtgtg ccctgatctc gggcaccagc ggggggcaga gatcctccgc
    70741 aggtgggggt acggtatact ggaagagttt tgaccggtcc accaaccagc acagtccaac
    70801 tgcccgtccc cgggggg
//
LOCUS       DAOOJU010000006        70001 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_441_length_70001_cov_15.138993, whole genome shotgun sequence.
ACCESSION   DAOOJU010000006 DAOOJU010000000
VERSION     DAOOJU010000006.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 70001)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 70001)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70001
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_441_length_70001_cov_15.138993"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            140..748
                     /locus_tag="PK679_02760"
     CDS             140..748
                     /locus_tag="PK679_02760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RlmE family RNA methyltransferase"
                     /protein_id="HPC54912.1"
                     /translation="MGSQWGRDSAYVRAIREGYRSRAAYKLKEIQERFHLIRDTDNVL
                     DLGAAPGSWLQVTRSITKGRVLGIDLAPIAPLEGVTTLVGDITDPRMRMEARSILGTV
                     NIVLSDASPKLSGNRSYDQARAIGLGEDVLSFACAVLKPGGNLLMKSFQGEDFSGLLD
                     DVRQHFLSVKTFRSRASRKGSSEIYIIARNFVECHGEAEGPV"
     gene            723..1604
                     /gene="moaA"
                     /locus_tag="PK679_02765"
     CDS             723..1604
                     /gene="moaA"
                     /locus_tag="PK679_02765"
                     /EC_number="4.1.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004075835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HPC54913.1"
                     /translation="MVRLKDPFDRPVSNLRVSLTSRCNLSCIYCHAEGEERPGDQLSC
                     SEIAEILRVADRFEIRHVKFTGGEPCLREDLAEIVSLVPDKMECSLTTNGTLLADMAG
                     DLADAGLSRVNISIDSLNRETYTKIAGKDCLSDVLAGIEAALDAKLVPVKLNMVVLSG
                     INDHEVDDFVRFVRGNRNLVLQLIELLGFRDCDHHYNLRDLETRFAKNAREIFTRRMH
                     HRRKYCVDNAEVEIVRPLHNTEFCAYCNRLRVTSDGKLKPCLLRSDNLVDIRGASGEK
                     LEELFREAVRRRAPYYR"
     gene            1695..2225
                     /locus_tag="PK679_02770"
     CDS             1695..2225
                     /locus_tag="PK679_02770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54914.1"
                     /translation="MNADEEYVRVLEHLYEKSLVLHDTSLWDPVLHFFFLDALAHLDY
                     TLGILSYTYQSPKNIMAQEYMRWRIDEEKKGNRQHFPAFMSWLAKNHPDRYTRLPTLW
                     QRIYDPDDPASYRSFRIVLDPDSQQVIKPHVFFRMIDEFFDREFLKSLYSEDGSLSRL
                     FAEFMKERRSMSVPGN"
     gene            2232..3449
                     /locus_tag="PK679_02775"
     CDS             2232..3449
                     /locus_tag="PK679_02775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HPC54915.1"
                     /translation="MGIADLCATLVRIKSENPPGDTRDVIEYIRDFCSGIGLGMKVVK
                     RRGGRHNLVSAKPRGKLLFCGHVDCVPALPDGWSDDPYGGTIRDGKVFGRGTTDMKGG
                     CAAVLWACREWMESGRDLPADLAFVCDEETSGTYGIRTLLARRAIIPCDCIIAEPTPP
                     FSPNVGQKGIMRLCCTFRGEPGHGSLYPEKGVSAIMEAYRLLDFVKDLHGVSFNPGDP
                     GLSGLIRDSAAILGDLLDIPNAYDILTRVMYNPGTIQGGEKANIVAQQCRLELDLRIP
                     WGCNLESLLCDLKRHAPRGDIAVTNMAEPSLTPPDAPLVSTLLQEIEKVYKRPARPVV
                     QWAASDARYLRKEGFSVVEYGPGEIRTLHAIDEYVTIESLVNASRVYRGMLAHYAGAK
                     KRVSSLSLGRSVS"
     gene            complement(3818..4330)
                     /locus_tag="PK679_02780"
     CDS             complement(3818..4330)
                     /locus_tag="PK679_02780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54916.1"
                     /translation="MALMEVIWSFFFPLVGAAVAIVHIRWKHLTGIAAMETFLAWQLA
                     VGLGLSYVYAGFGHLVFPDRVAMSIGWPAGSPFQREVGLWDLSIGVTGLLCLKVRPMG
                     FWLATVIAFGIFSIGAGIGHVYELVVHGNASINNAGPVMYMDLLYPVFLGALLALYDR
                     MKKRMQIRQV"
     gene            complement(4439..5782)
                     /gene="gltA"
                     /locus_tag="PK679_02785"
     CDS             complement(4439..5782)
                     /gene="gltA"
                     /locus_tag="PK679_02785"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HPC54917.1"
                     /translation="MGERPADERVRDFSEVDTGLSAEEAVAEAQRCLQCKKPSCVKGC
                     PVEIDIPAFIARIAEGDFAGAAQVIKENNLLPAICGRVCPQEVQCEGQCILGLKEVPV
                     RIGELERFVADHERKTGSRLPPKAEPTGKKVAVVGSGPAGLTAAAELARLGHSVVLFE
                     SLHEPGGVLMYGIPAFRLPKEVVRAEIDQLRGMGVTILTNHLVGTSVPVSELLSYDAV
                     FLGCGAGLPHFMGIPGENLNGVYSANEFLTRVNLMHADRFPEFDTPVRHAGRVVVVGG
                     GNVAMDAARVARRLGARTTLVYRRRKEDLPARRAEIARAEEEGVTFVFCASPVRILGE
                     QCVTGVECERMEMCATDASGRPEPVPVEGSRFVIDADMCIQAIGQGPNPLLVRMLPGI
                     RTGRRGNVIVDEEGRTDLGKVFAAGDIATGAATVILAMGGAKRAARAIDRMLRNS"
     gene            complement(5775..6665)
                     /locus_tag="PK679_02790"
     CDS             complement(5775..6665)
                     /locus_tag="PK679_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HPC54918.1"
                     /translation="MTLHFSRQGEDEIVGYRVKEASPMAERIYQIWIEAPHVARNARA
                     GQFLVIRIDEKGERIPLTISAVKGDLVRVIFMAVGKTTYQLATLVAGDEIRDVAGPLG
                     KPSEIGHFGHCVIVGGGAGIACCPIIARAAKAAGNRVTGIIGARSAGFLILEEEMGET
                     CDELFVATDDGTKGHHGFAADVLKQVIGKERPDRVWIIGPAIMMKVTSEVTRAAGIPT
                     LVSLNPIMVDGTGMCGSCRVVVGGETRFACVDGPEFDAHKVDFDTLMARQKTYLEEEK
                     LALERFSSHHCGCGGRDHHG"
     gene            complement(6662..8311)
                     /gene="arcS"
                     /locus_tag="PK679_02795"
     CDS             complement(6662..8311)
                     /gene="arcS"
                     /locus_tag="PK679_02795"
                     /EC_number="2.6.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002948 - archaeosine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0002927 - archaeosine-tRNA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaeosine synthase subunit alpha"
                     /protein_id="HPC54919.1"
                     /translation="MSRFEVIRRDGLARISHLSVEGRDIVLPSAGEADTLFPGLAGSS
                     LENVPLDADPGFAARYLPAGETLPVRVHPAVDRDVGSGTCVMVPCWHTALADPRKYVE
                     WLVRLKERLPPDTAFYAPAAAVPSNISLLCYTGFDLFDFTAVDLASARGEFCLPEGVF
                     PADLMEEGACSCPGCREGDLLRHNRAALLRELALVRMHIASSSLRDLVESRSRMDSRY
                     VSIIRFLDRESHFLEPRIPVSRPGTFLATSGESLFRTEVRRFADRVVNRYIPPAADVA
                     VLLPCSAKKPYFLSQSHRRFMEAVSGRALELIVTSPLGLVPRDLERVYPAAHYDVPVT
                     GYWDAEEKAWIAGVIAQFFRKHRFRRVIAHLEGGALDAAGMAAEMASIDLECTTGGDR
                     ATSRAALNALSGALSGEKPVTHDLVRATASYQFDTAVDTKGFTLKERFPDLKVFRGME
                     PLFSLDPGTGLLRPTFGGWELIPAGYRVEIDSFVPSGDILAPGVVGADPRIREGDEVF
                     VTGPLAVATGRAAMPGPEMVRSRRGVAAKVRKVKTPGGKHV"
     gene            complement(8308..9753)
                     /gene="tgtA"
                     /locus_tag="PK679_02800"
     CDS             complement(8308..9753)
                     /gene="tgtA"
                     /locus_tag="PK679_02800"
                     /EC_number="2.4.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(15) transglycosylase TgtA"
                     /protein_id="HPC54920.1"
                     /translation="MVILFEILEEDIAGRTGRLKVGERVVRTPILLPVVNPHLQPVLP
                     KEMKALGAEGLITNAYIFSRSEEFRDRALASGLHEVLGFDGLIMTDSGAFQLSVYGDI
                     SLTNGEVIRFQQDIGSDIIVPLDIPTPPSADRATAERDLSVTMSRLGEALALCGERNN
                     VAGPVQGGIFPDLRERAGRSVGEMGFSFCPIGAVVPLMESYRYRELVQVVMAAKKGIP
                     SSSCVHLFGAGHPSMFALAVAMGCDVFDSAAYALYAREGRYLTPSGSAKLQEMGELPC
                     ACHVCRSHTAEELRQSEESERLLAIHNLSVSLAEIARVRQAIADGVLFELVDERCRSH
                     PLLLDGYRAFLRHGEALEKRDRVSKRRFFYRGQESCLRTEVIRYHALLQRLDLPSRVV
                     ISLDGTGREGFDLTLFFKPPFGPYHPALCETFPIGQCELPCWDNEMVSAGCRGMRVLM
                     ESHPETEFSVTCPLEWRDLLMSELPGVQVIP"
     gene            complement(9875..10432)
                     /locus_tag="PK679_02805"
     CDS             complement(9875..10432)
                     /locus_tag="PK679_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00296 family protein"
                     /protein_id="HPC54921.1"
                     /translation="MEVLTPEEGRVAVQLARAVLEEKIGRKHVDYPALPPVFSEKRGV
                     FVTLKKRGELRGCIGFPTPVYPLGQAISGAALAAALEDPRFPPLRAGELPEIRIEVTV
                     LSVPVPLTCRASERPRNIMVGTHGLIVRGMGRSGLLLPQVPLEWGWDAPEFLDHTCLK
                     AGLARGCWKDERVEVYTFEGQIFGE"
     gene            10467..10822
                     /gene="rnpB"
                     /locus_tag="PK679_02810"
     ncRNA           10467..10822
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PK679_02810"
                     /product="RNase P RNA component"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00373"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="archaeal type; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00373"
     gene            10881..11441
                     /locus_tag="PK679_02815"
     CDS             10881..11441
                     /locus_tag="PK679_02815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC54922.1"
                     /translation="MHVPTPEEIRARRELLGMKQADLAEKAGISQSMVARIERGSVDP
                     RVSTLRKIVGVLNAMEKPRVTAARVMHTPVICVGIDDPITRAADIMEKHGISQVPVLE
                     GGIPVGCISESAILSAINNRATHRAPGDQVRYYMESGFPTVPKDTDIETVIRILEHHH
                     AVLVMDGGRVAGVITTHDLISLVRNH"
     gene            complement(11438..12106)
                     /gene="tpiA"
                     /locus_tag="PK679_02820"
     CDS             complement(11438..12106)
                     /gene="tpiA"
                     /locus_tag="PK679_02820"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HPC54923.1"
                     /translation="MPKPFILINLKTYMEASGQRAHSIAGAAQQVAEESGVEIGIAPS
                     YMNIHPLSMHYSLPVYSQHVDAALPGANTGAVTVEAIREAGATGSLVNHSERRLTLAD
                     IEAVVSRLREADLVSVVCTNNVATSAAAAALGPDFVAIEPPELIGGNVSVSSANPGII
                     TGTVEAVRKVNPSVRILTGAGIHSGECVKTAIDLGTDGVLLASGVVKAKAPIAVLRDL
                     VSRL"
     gene            complement(12178..14763)
                     /locus_tag="PK679_02825"
     CDS             complement(12178..14763)
                     /locus_tag="PK679_02825"
                     /inference="COORDINATES: protein motif:HMM:NF013316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HPC54924.1"
                     /translation="MSGAGSAGKTKRPPELLAPAGSGEALQAAIAAGADAVYLGGKRF
                     GARQYAANFSPGEMEEAVQVSHLAGVRVYVTVNTLIREGELSGALSFLFDLYRMGVDG
                     VIIQDTGLLSLARKTVPGLALHASTQATIATPEGAAWAKAAGYSRVILPRELTLDEVD
                     GILALPREKRPEIEVFVHGALCYSYSGQCLLSSLIGGRSGNRGMCAQPCRKPYVLVEM
                     GPRKGDSGQGYPVLRTRERYLLSTRDLCCYPGLDRLFQREIAALKIEGRMRSPAYVAI
                     VVRAYRRALDALRNGNAHYRPEDEEAMALVFSRGFTGGFILGDPVLMGREAPGNRGLL
                     LGTVRAVVPEKGLIIGAAAQILPAAGDGILVASPGGEARGGFSLKTGGSRREGELFLP
                     APVRGARPGDLVYLTRSRSSRENMKAVTGEGRMRRPVPVDLDVAISTGEPVRWKASVH
                     HPVRGRIAIEGSAGEVPVPARTQPLSPGTVRSQLGKTGDSPFVWGHISVSMGKDAFLP
                     LSSLNSVRREILDRLEREWIAAFHPLPPELGAARSAVAAVIQDMATHQAGYARVMEEN
                     ARPIITVYCATPGELEAACTCGSDAVRFEPTAGDGGDDWSGEVLEGARTCREAGVHFA
                     WMWPRVAPPAFVRKELDRLPDLFVRGVPGIMAGETGLAEAIRARVPEMEVLGGPGLNI
                     VNSEAALFLHPPIDRFTLSPEIPRADIPVLISRAVTKCPGLSFEVICQGNIEAMVSRN
                     RLLTDLLGEHGPGHYGLKDETGRVFPVYEDRLGRTRILNAVETTLIDHVPFLIGAGVR
                     SLAIDARRRGPEYIHEVVPAYRRAAELCHAGKNDPGTLEPLKERIRRVARGGLTGGNF
                     VRSSF"
     gene            14821..15450
                     /locus_tag="PK679_02830"
     CDS             14821..15450
                     /locus_tag="PK679_02830"
                     /inference="COORDINATES: protein motif:HMM:NF013640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HPC54925.1"
                     /translation="MRFVASVPDISFIPAALASGADVIEVRLDLTGSVSPEEANATFR
                     DLTVPLIFTVRSAAEGGMFAGGPEEWWDMVRPCLPYATFIDVERSFRSFAPVLRREKK
                     TIIASFHTPSMPDPGSLEALRRDLAGYGDIPKIVVGPRSEEDVLSLLSFTLHAEKPII
                     TSVMGSRFSFIRLMLPFFGSSFIYCHAGSPAAEGQIHLSRAREIMGLFR"
     gene            complement(15695..16138)
                     /locus_tag="PK679_02835"
     CDS             complement(15695..16138)
                     /locus_tag="PK679_02835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54926.1"
                     /translation="MIKPRRKSEENHALRAALIMCLAALVFLSCAGCVSVLTQADGER
                     GDAGAGNGTAMRAILVRQNADWGISRGCTWETTFQVYNPGTTEERNVFLHVELVNADT
                     GAVRDTKELYLGTISPGEERIVTLELDGECLKEYTVRAIPLVRAL"
     gene            complement(16214..17230)
                     /gene="aroC"
                     /locus_tag="PK679_02840"
     CDS             complement(16214..17230)
                     /gene="aroC"
                     /locus_tag="PK679_02840"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HPC54927.1"
                     /translation="MNTFGKNFRVTTFGESHGPALGAVIDGCPPGVEISEEEINRALE
                     RRRPGIHPFSTRRKEEDRVRILSGVFMGRTTGTPLCLLVRNTDARSSDYEALADVFRP
                     GHADYTYQVKYGIRDFRGGGRSSGRETVARVAAGAVAEKILSGRGISIRSRVLEVHGA
                     TLPEEMEREIADAARSGDSVGGIIEITATGCPPGLGDPVFGKLDALIAMAMMSIGAVK
                     GVEIGDGFAAARMRGSEHNDQMDGSGFLSNHAGGILGGISTGAEIVVRIAVKPTPSIS
                     REQRTIDTAGRETTISVTGRHDACIVPRIGPVAEAMLALVLADACLGRQMLRSWVPGS
                     METL"
     gene            complement(17227..18612)
                     /gene="aroE"
                     /locus_tag="PK679_02845"
     CDS             complement(17227..18612)
                     /gene="aroE"
                     /locus_tag="PK679_02845"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HPC54928.1"
                     /translation="MKVVLIGFRGTGKTAAGHLLARLLGVPFYDTDALIEEKAGAHVH
                     EIFGAVGEEGFRKLEREVIATLPSGPGVFATGGGAVLSPENVEHLRRGRTVVLLQADA
                     ATIEKRIRDTARPPLTTMGLRAEIQHLLSVRRDAYLSAADMCVDTSARSANEVAIHIK
                     RLLEEGTVPVEGMEKAARAIAQSGIPEQEGRELLEKIGAIRDNPVLRFYGVAGYPSLH
                     SRSPQLYAQLFSYFGINAHYIRFHDPSLSRILNLAADLDVRGLSVTIPFKQEVLDAVD
                     HPDEHCSAIGAANTVLFCGGRSYAYNTDWMGIRDALLEEKGKTAVVLGAGGAAAAAAY
                     ALLSLGMEVTVLNRTVEKAEALAARFGCSSGVPRDFDRIRPAVVVNATPVGMEPDRGS
                     PLTREQLFPGMTVFDLVYTPPETPLLRMARSAGCRVIQGREMFIRQAQAQFRHFTGID
                     APLHMIREMMG"
     gene            complement(18609..19877)
                     /gene="aroA"
                     /locus_tag="PK679_02850"
     CDS             complement(18609..19877)
                     /gene="aroA"
                     /locus_tag="PK679_02850"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HPC54929.1"
                     /translation="MDLTLRKAGPLDCTFVAPPSKSYTHRALIAAALAPGESHVADPL
                     VSDDTGVTRNALESMGIPMREWEDGLLVSGRGGSLSCPDGLVIDTGESGTSMRLLCSV
                     ALLCRRPVTLTGSRRMKERPVGPLAAAIRALGGEVGFLGREGYPPVRVSGSLDGGEIT
                     IDAGISSQFVSSILLVAPLARKDVTVTIGGNVASQSYIDVTISVMEAFSAMVEREGYR
                     RFHVPAGHGYRPSRYRVEGDYSSASYFFALAPLCGGRVVVKNLNPRSCQGDRAFLDCL
                     ERMGCHVKSGKDWVEVSSDGDIDGITVDMTSFPDTVQTLCMVASKARGPTRILGVGHL
                     RYKESDRPAETARLLSTLGAGVRVENDSITIIPRPLHGGEIDPGSDHRTAMSFATLGL
                     ATGNLKIRNAECVSKSFPGFWEQLSKQGLV"
     gene            complement(19868..20668)
                     /locus_tag="PK679_02855"
     CDS             complement(19868..20668)
                     /locus_tag="PK679_02855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase domain-containing
                     protein"
                     /protein_id="HPC54930.1"
                     /translation="MKVFALGPEGTFSHELGWRIFGEAVTLVPTIRRIFEAVEKGEGD
                     GLVPLENSEAGGVGASMDGLLTFKVWITGETCVPVHHYLVSLGPLAEARVIYVHPQTH
                     EQCSDIIEELGIPVVHTPSNAQSARELVRSGRGAAIVPKMTARLYDLPVQKACVENSD
                     QNVTRFVTISSRPYGGSRPVKGSIIVDPREDRAGLLHDILGVFSGKGINLTRIESRPS
                     KRGIGSYVFFIDYQFSGEGSLAALEELKEMTCVKDLGRYPVLEVPEWT"
     gene            complement(20665..21489)
                     /locus_tag="PK679_02860"
     CDS             complement(20665..21489)
                     /locus_tag="PK679_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase/arogenate dehydrogenase
                     family protein"
                     /protein_id="HPC54931.1"
                     /translation="MKVGIIGGTGKMGTFFGNVFSRAGHDVMVSGRSTKTRDVDIANQ
                     CDIVMVSVPIRETVRVIRQVAPLLSEEQVFCDLTSLKAAPVRAMLESRARVVGLHPMF
                     GPSAESLHRQTIIATPARCDEETLGNLLEIFRSQGARVTITTPEEHDRMMAVVQGLTH
                     YVTLGMAGTMRRLGMSPEDTMAFMSPIYQIEMCLVGRLLSQDPDLYADILMLNPEVPA
                     VLSACNESFADLHGIVTKGDADEFRRFFLENSRHFGDYCARAAGESDMLISAMVRR"
     gene            complement(21496..22482)
                     /locus_tag="PK679_02865"
     CDS             complement(21496..22482)
                     /locus_tag="PK679_02865"
                     /EC_number="1.4.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase II"
                     /protein_id="HPC54932.1"
                     /translation="MKEFWVDARPWRKNIATAALESGAGTIVADSAAGVKALGRVRVV
                     APDGDLVPGRDVFEIAITGRESEELAVEKAREGYVVIDADDWKVIPLENLVARSDRII
                     ARVTSPQEALLALQVLEKGVAGVLLDTDDPAAVKETGTLMHRGQEEVSLVPFTITAVR
                     PAGMGDRVCVDTCSLLSEGEGLLVGNTSSAFLLVHAETLENPYVAPRPFRVNAGAVHA
                     YLLSPGGKTSYLSDLSAGDRVLVVDRDGVAREVTVGRVKIEKRPLLLVEAEADGVPCS
                     LILQNAETIRLVAKDGSAVSVVGLSAGDTVMGCVKEAGRHFGMAVRESIVEK"
     gene            complement(22483..23265)
                     /locus_tag="PK679_02870"
     CDS             complement(22483..23265)
                     /locus_tag="PK679_02870"
                     /EC_number="2.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate
                     synthase"
                     /protein_id="HPC54933.1"
                     /translation="MIGKEIRIERIMDRNTGRSVIVPMDHGFTLGQIEGLKDMTRTIS
                     EVSEGGANAIVLHKGIVKRGHRRKGRDIGLIVHLSGSTSLNPDPNDKVLVCTVEEAIA
                     LGADAVSIHINLGAPNESRMLESAGMIVKDCNRWGMPLLVMIYPRGKGINPTSPESVG
                     HCVRVAEELGADLIKTNYTGDPKTFADIVSACSVPVFIAGGEKAGDLETLEIIRDSVR
                     AGGAGVCVGRNAFQRENPRAFVEALCKVVHEEMDPKKALKGD"
     gene            complement(23262..24062)
                     /locus_tag="PK679_02875"
     CDS             complement(23262..24062)
                     /locus_tag="PK679_02875"
                     /EC_number="2.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate
                     synthase"
                     /protein_id="HPC54934.1"
                     /translation="MRGKEIRLERIMDRNTGKTIIVPMDHGVTSGPIEGLIDLGRAVD
                     LVAEGGANAVLGHVGLSLHGHRRSGRDIGLILHLSASTSIGPDPNEKVLVNTVTNALR
                     MGADAVSIHINIGADSEARMLADLGRTAVECMEWGMPLLAMMYPRGRKIENEHQVSHV
                     SLAARVAAELGADIVKTVYTGDPDSFREVTRGCPVPVVVAGGSKTSDLATLEMIEGAM
                     EGGAAGISIGRNAFQHPTPDRFIAAAALIVHHGRSAEEAYKVLQEKRS"
     gene            complement(24324..24842)
                     /locus_tag="PK679_02880"
     CDS             complement(24324..24842)
                     /locus_tag="PK679_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein bridging factor aMBF1"
                     /protein_id="HPC54935.1"
                     /translation="MSIKMFATSMQCEMCGAKIQGQSKTVRVEGAVLEVCAQCARYGT
                     EVPKIQKPVQRTGTALRAPVVQPEKRKRDVFDFIEGEIVEDYGERIRTARMERGWSQK
                     DLAMHLKEKELLIKKIEKGDLIPEDDVRKKLEKALNIRLIDSPSAEESARQAGKVVPT
                     LGDVISLKKVKK"
     gene            24874..26112
                     /locus_tag="PK679_02885"
     CDS             24874..26112
                     /locus_tag="PK679_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome-activating nucleotidase"
                     /protein_id="HPC54936.1"
                     /translation="MVESARQSQEPQNPEELYRYLLDRVTHMETRNLELREQIRQIES
                     DKRYIETQKIRYEREVRKLKSEIEQLRSPPLIIGTITDVLDNGRVVVRSSAGPRFMVR
                     SSMCIDPEKLKPGVRCTLNQQSLAVIDILPESYDAQVYGMEVVESPDETYADIGGLDA
                     QINEIREAVELPLRRPELFERVGIEPPKGVLLHGPPGTGKTLLARAVAHETNAHFLRV
                     VGSELVQKYIGEGARLVRELFDLAKKKAPTIIFIDEIDAVGASRTESTTSGDREVQRT
                     LMQLLAGMDGFERRGDVKIIGATNRIDILDRALLRPGRFDRIIEIPLPDILGRVAILK
                     VHTRKMNLDENVDLEEIARLTEGKNGADLKAICMEAGMFAIRREREAVSKEDFLDAIE
                     KIGQDFERHVIRTGYGAMFA"
     gene            26275..26580
                     /locus_tag="PK679_02890"
     CDS             26275..26580
                     /locus_tag="PK679_02890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MscL family protein"
                     /protein_id="HPC54937.1"
                     /translation="MSMLKEFMDFLYEYKVIGLAIAFIMGLAANQLVKSLVDNIIMPV
                     ITFFIPGGDWQTAKLAIGPIIISWGQFLSDLIYFIIVAFVIFLIAKKVLREDKVTKK"
     gene            complement(26567..27049)
                     /locus_tag="PK679_02895"
     CDS             complement(26567..27049)
                     /locus_tag="PK679_02895"
                     /inference="COORDINATES: protein motif:HMM:NF039541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5804 family protein"
                     /protein_id="HPC54938.1"
                     /translation="MVFVPREGVDLYSALLSSETSREALRFYQPARTPAGVEVTPASL
                     GSALSLVSDLRWYVRRYMHDVIFEIAPGTFCTADIARMIYYGREPVLQKRWKYRRIYS
                     FREGRLVSDEPLHARADSGKKAPENSGEGEMRIEVWCTRDQYLAKRGSDREDFPVTSS
                     "
     gene            complement(27160..28323)
                     /locus_tag="PK679_02900"
     CDS             complement(27160..28323)
                     /locus_tag="PK679_02900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome-activating nucleotidase"
                     /protein_id="HPC54939.1"
                     /translation="MEESVIKNAGTDTEIKIQLKIQDLESQVLDLKVRNDELLRENAQ
                     LKRENNQLKRMPLFVAVVVDLLGKGEVYLRQQGNNQEYLTHVNDELFRQLKPGTKVAV
                     NNALSIVKIVGSIFDSRVRVMELEESPKVTFSQIGGLSKEIEEVREAVEYPLTKPEIY
                     ERVGVEPPKGILLYGPPGTGKTLIAKAVAHQAKATFIRMSGSELVHKYIGEGAQLVRE
                     LFALAREKSPSIVFIDEIDAVGSTRTNDGTSGSAEVQRTLMQLLAEMDGFDTRGDVRI
                     MAATNRVDMLDPALLRPGRFDRVIAIPLPDDEGRLEILKIHTQRMALGKDVDLSAIVG
                     MTKGATGAELQAICREAGMNAVRREAAAVSQEDFLQSVRKVRNEQSPDLRMYI"
     gene            28362..28796
                     /locus_tag="PK679_02905"
     CDS             28362..28796
                     /locus_tag="PK679_02905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF126 domain-containing protein"
                     /protein_id="HPC54940.1"
                     /translation="MIVIIRGRGISGGCGTGQALVSPAAISFLSGVNPETGTIVEKGH
                     PLEGQSIAGRVLVFPHGKGSTVGSYVIYALSRNGKAPAAMVNEEAEPIIAVGAIIGRV
                     PLVDRLEGGLSRLRDGDLLRVNGDMGTVEILENGEDPRRREK"
     gene            28850..29278
                     /locus_tag="PK679_02910"
     CDS             28850..29278
                     /locus_tag="PK679_02910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54941.1"
                     /translation="MIILLILAVSAIAFAGCTETPSMSSQNGGPVGIGGSSFATGPTV
                     TLPPEQNVEIQVNEKDPIYATITVVFAGGKGQIAVRDILVRVTTSDGKVTEQHLPPQK
                     GSEVVFKGTKGDDRLEVTVTLTTGATYKIIDRIIPYRTRG"
     gene            29365..30465
                     /locus_tag="PK679_02915"
     CDS             29365..30465
                     /locus_tag="PK679_02915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04013 family B12-binding domain/radical SAM
                     domain-containing protein"
                     /protein_id="HPC54942.1"
                     /translation="MDVCWRYIPAARNSYAALYAACEKEGFVLRPVDTPQGDVTCYSL
                     NSLNAHQYIPEMKRAPCITIAGGPHATACYAEIASIADYVVVGEGEYTLPALLASIEN
                     GSPLPRGVATRESYSCADTCVRLDAFPAFSRMKGYIEISRGCPHACTYCQTPRIFGPA
                     MRHRSIDAIVGAARKFRDARFVTPNALAYGSDGIHPRLDKVRSLLSALRYPGQKIWFG
                     TFPSEVRPEWITEEALDLVTTYCSNRRLHFGAQSGSNRVLSMLQRGHTVEDAERAIDL
                     IVDAGLTPVVDFIVGLPCETEEDQEMTAAFIRWTASRGQVHVHRFIPLPGTPLAGLPP
                     RPLIPGLESLLGNLALKGKLTGTWRDRTKSFF"
     gene            30490..31131
                     /locus_tag="PK679_02920"
     CDS             30490..31131
                     /locus_tag="PK679_02920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HPC54943.1"
                     /translation="MRDVLLLADLHGEFGKIGSFLDLAPDAIIIAGDITNMGPADAVE
                     SLFDRIDVPAFAVPGNCDPRETVDALERSDCVCLHGSSLSLGNITLVGIGGSNPTPFS
                     TPFEMTDKQIDDILSPLVARMERRTHNVLISHAPPLGILDLAGGNHVGSASVRKHMAS
                     FDLVCCAHIHEQRGVAEESGIRVVNPGMAALGQCAMLHFGDEPRSIRIELTQV"
     gene            complement(31146..31676)
                     /gene="cyaB"
                     /locus_tag="PK679_02925"
     CDS             complement(31146..31676)
                     /gene="cyaB"
                     /locus_tag="PK679_02925"
                     /inference="COORDINATES: protein motif:HMM:TIGR00318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IV adenylate cyclase"
                     /protein_id="HPC54944.1"
                     /translation="MLEVELKARVDDLGAVRERLHTMQAVFECAVTERDLYLNSPARD
                     FAKTDEALRLREAGGHYTLTYKGSRKTGHPLKAREEIICGIESGETMEKILVALGFRP
                     VAEVRKRREYYHVRDATVTLDSVEGLGEFVEIELDSHAGVPASYLIDLAASLGVTGKP
                     IQDSYLELLEKSRKKG"
     gene            31897..32580
                     /locus_tag="PK679_02930"
     CDS             31897..32580
                     /locus_tag="PK679_02930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HPC54945.1"
                     /translation="MAIQKGDFIRLSYTGRVDGTVFDTTDEEVAKEAGIYNPEAIYGP
                     VTVRVGSQHVIIGLDEALEGREVGEEGELEIPPDKAFGPHDPSRVEAYNKNAFREKPK
                     KGMTLKVPEKGEGKVVDVIGNRVLIDFNHPLAGKTLSYRFRVDECVTEPVEQVRGLIR
                     LYAGRDMDVSLDSGVLTIHLPPGITYDRRWLLWRSRVIQETFSAIPGIARIVLEETFN
                     RPGESEPVE"
     gene            complement(32611..33960)
                     /gene="purB"
                     /locus_tag="PK679_02935"
     CDS             complement(32611..33960)
                     /gene="purB"
                     /locus_tag="PK679_02935"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HPC54946.1"
                     /translation="MAIHPIEYRYGTEEMRRIWSEDFRFSCIVRAEVALAQALARHGL
                     IPARAADAIAAGAGRATLSRAKEIEEEIHHDMMAIVRAIAEHCGEGGGYVHFGATSND
                     ILDTATGLQLAEATRVFDRKLRRLLAVLVRRAGETRVLVCAARTHGQIGVPTTYGLRF
                     AIWASEIARHIERLGQLKARIAVGQLTGAVGTQAAIGGKGMEVQATMMELLGLSPVDV
                     SNQVISRDRYAEYFMFLANVATTLDKIGIEIRTLQRSEIGEVEEPFGSRQVGSSTMPH
                     KRNPIRSEQVCGLARVVRSSVSPALENNTLWDERDLTNSSCERVLFPEASVLADHILS
                     VMTGVLDGLVLKPDRIEANLSLLHGINMAEAVMIALAERGMDRQKAHEILRQASMEAL
                     ERNVPLIEVLSGNSDVTKIIPVNEIRALLDPARYIGTAPAQVDRLIEKLSPLCREAL"
     gene            34021..36024
                     /locus_tag="PK679_02940"
     CDS             34021..36024
                     /locus_tag="PK679_02940"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HPC54947.1"
                     /translation="MTGLEDFFPYPGFRPHQREMLEFCSACARDGGIALIDAPTGSGK
                     SSILAALVAGGGGRRVLVAVRTVSQLNTFIREASLIRRKKRDLRVAYLVGKRGMCPLS
                     GEGDVYRRCEGVKAFSSTLMRQRAENGALVPSRDPFIRQQIQRMDPQRPILCPFFIAS
                     RVFIRSESGLRMAPSPELRAAADRVLREDVWPRQLQDVAHPVCPYEMMVLAAQKADVI
                     LLNYQHIFDEEISRTLFANLDIDPSETILLIDEAHNCGDAVSAAQSVAIDQVILDQAG
                     QELAGFARKKGTAAALQQVLPRISEFMDGVKNSPEAEDWFDPGIFDRMVVRGSLYRDM
                     GAIVDDLMELSEKIHEKNMRDGDFHESAIEKLTRFLFSLSGSSHDPSFLTLFQKDEGR
                     VTLEVRCIDPGIRLSEIGSSHHACILISGTLSPVESYARLYFRDIAVRTLSLPNAFPR
                     KNRLVLCAKDITTAYSMRQNESNLDLIEDYIREFSNLPGNVAVYFPSYQFLDHYAGRL
                     GERLGNKVIYVEPRDAREADESLREFLSLPGSGRSGILLAVCGGKWSEGLDYRGELLR
                     AAMVIGLPLAPFNHVRKMIIEYYRRRFGEEGEFLCYTLPAVNRAQQALGRVLRTPEDR
                     GVLVFGEKRFLEGRVNRGLSPWIREELHPCLFSDFKKVVRSWK"
     gene            36021..36464
                     /locus_tag="PK679_02945"
     CDS             36021..36464
                     /locus_tag="PK679_02945"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HPC54948.1"
                     /translation="MREGSCRLGLWHVHVYWEGSTVSRVRFSRTPLPGPVPVQFRRYC
                     AGKREDFAGLTSIALSHEYPYSAIYSEVRKIPYGETRTYGQVGSALHVSPRLVGLAMK
                     RNPTPLIIPCHRVVSRNGIGGFSPDPELKGVLLSLEQKNKRVLSR"
     gene            36585..37181
                     /locus_tag="PK679_02950"
     CDS             36585..37181
                     /locus_tag="PK679_02950"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HPC54949.1"
                     /translation="MTRRSAIILVGGEAKRANGQEKYFFTMDGRTFIERLIGSLEQVV
                     DEIVLVAKDPAQCQRFSHLGGVRCVTDIRRGRGPIGGIHAGARAATGDLVFVCACDMP
                     CVSPGVVRELFSLIGDADAVIPRWDGEMLEPLHAVYRRTSLISCLERQDPPSLRALAG
                     SLHVVFVDARSFGEIDPGLRTFTNINSPEDLSSLSRGA"
     gene            complement(37167..37859)
                     /locus_tag="PK679_02955"
     CDS             complement(37167..37859)
                     /locus_tag="PK679_02955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54950.1"
                     /translation="MKGGGIVCLLVIILVVAVLACGCITPPKESKGKITQGSGGTGTQ
                     EATTAPTQNIIDTRVVTQATPFPTPLPPETPVSYSKMPEPTYEQTVYKAVYRNVIPFS
                     NNATAYSVTVENPPLIIEICISPKMVTRNIWYESRFTTRDDVYVTQTVISPNAYLEVK
                     VRDRASGNIIAQDGFARTYSVDRYRVLTIRSAGDYLVEFSGNDLSATVQMRVPAGPGA
                     DVTPVATLSCPS"
     gene            38007..38408
                     /locus_tag="PK679_02960"
     CDS             38007..38408
                     /locus_tag="PK679_02960"
                     /inference="COORDINATES: protein motif:HMM:NF019339.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC54951.1"
                     /translation="MEKKEGFWKKVDRSLNVADGYVLKADMLAHDRRFEEAVEYYDKA
                     LEIVPGNADVWAFKGITLQGGLGRDEEARKCWERAKSLDHTLAMAVDMTKEETGRGVE
                     VESIPWSDLKDSCRDKLKRMMLKQAQSERKG"
     gene            complement(38416..38604)
                     /locus_tag="PK679_02965"
     CDS             complement(38416..38604)
                     /locus_tag="PK679_02965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54952.1"
                     /translation="MVDITAYTVISIVTLCFGLLVGFQVAHIMYVRRLTRLAKRCVDT
                     GTIAPVLVEMEIAESPEK"
     gene            complement(38625..38801)
                     /locus_tag="PK679_02970"
     CDS             complement(38625..38801)
                     /locus_tag="PK679_02970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54953.1"
                     /translation="MDELVIYLIIAVLMFVIGLVAGHLVMNTYYSRRFLAVAKECERA
                     DSIVPLITEMERES"
     gene            complement(38895..39512)
                     /locus_tag="PK679_02975"
     CDS             complement(38895..39512)
                     /locus_tag="PK679_02975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54954.1"
                     /translation="MEENRENQAGGVTVHPGIHEVTFWKTFATLRKMIRHLEERDLLI
                     AKLSKDPTLPEKTRDEVIACLKSEQAENLSAFHDFLVNFITIGMQGLHQTGITLEFSF
                     QENGTYRVLGASLHVDGTPLPLPDGEGRRLVSIISPVLLSGDDPGQALVAFYKSCEEM
                     HDRERGYGLDSCSLELTREIYPGTSFHARLRLPAYIFCRETPSGK"
     gene            complement(39499..39762)
                     /locus_tag="PK679_02980"
     CDS             complement(39499..39762)
                     /locus_tag="PK679_02980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54955.1"
                     /translation="MELMNIRPWIFFYLICFVALLLATTFIVQGITPLFWMSSTLIIV
                     VVGFNFILIFNEIREHRKRKALMQQISNPNKGNVETKGKNGGK"
     gene            40022..41191
                     /locus_tag="PK679_02985"
     CDS             40022..41191
                     /locus_tag="PK679_02985"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC54956.1"
                     /translation="MPTPSRILASAHQTLEERRDTVKLGIIAIFAVTSLIFTLYLIVT
                     RDQAFAASLYPLIPHLYLIPIILLALWYPRRGLQITLLLIAAILLLTTFLFLEGIVLN
                     PFIALLNAGMDIAIFVALALYAKDRTLVESFLRGFFEHSGLGETFEEAMEHPSVRAKI
                     KFEGAFEDVIRALHNPDEEVREEAARALGELGDGRAVEPLIGLLSDENRYVRREAAKS
                     LGKIGDERAIVPLINALKDEDRYGREGAAEGLGDMGEKAFSHLVSAMEDPDWHVRTGA
                     AVALRIIGDKRALPALTRAMQDENRFVRREVIKSLGRIGDHSVIDTLIAALKDPDRSV
                     RLRAVSALSKCNDPRVVEPLIEALNDEDSGVRLRVIRALEEIDDPRAVEALNNTI"
     gene            41344..41916
                     /locus_tag="PK679_02990"
     CDS             41344..41916
                     /locus_tag="PK679_02990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HPC54957.1"
                     /translation="MRKDQRNDDAFTGLEAAIVLIAFVVVAAVFSYVVLGAGFFTTQK
                     SQETVYSATKQASANLAESGPVVLETDGSSAVKNISFNLKPAAGASPIDLTRITYHLT
                     TTAQEALYVDQKANGTYKINRTQIIGDGDDLLETDEMFRVVLNAQDPGVEINKTAVFS
                     IEIKPDVGASLLLQKHAPPGLNADSFYEVY"
     gene            41918..42526
                     /locus_tag="PK679_02995"
     CDS             41918..42526
                     /locus_tag="PK679_02995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HPC54958.1"
                     /translation="MTRKNIDNERAFTGLEAAIVLIAFVVVAAVFSYVVLGAGFFTTQ
                     KSQETVYSATKQATSSFEVIGSVYGMANQTNAPYLSHVKFTIGNTAGGTAVDMTKVVV
                     EYTDEKQRWYGDEYGTPKDGITEDWLKTNTTPMWGILDRVNADTDDLLEPGEQYILGI
                     KLPNTTTPSTTFTLTLQPASGAAYPIVRRVPAGIDIVNILGT"
     assembly_gap    42596..42695
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            42914..43828
                     /locus_tag="PK679_03000"
     CDS             42914..43828
                     /locus_tag="PK679_03000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54959.1"
                     /translation="MAVSQSQVDHIIASASSDDPEVKLLKLQDEVELIKTSIKRLLID
                     IRERMNDLENPIVSAGGGASGEDVSAKMASVLKDTSSAIESAAGAIKSTAETKKTDEK
                     EDKGAGQDTRVSAQEQQVPQAYPSAQGVTQGVPATQPSVPPGKTDMDFLAALKSQLAS
                     LPKEEEGAKAAAGDKVRLQKVFRLFEWTSRNVKRFGHDRVDLMLDAYHAMGYISDKSC
                     KLVKDMARLMPTSIGELHEIRADEFVSELYELNHILNPSDSTLDRDMIEVLMEKREGR
                     DTQKYLAPGRHPREDAGEQGYLPSRDRP"
     gene            43835..44308
                     /locus_tag="PK679_03005"
     CDS             43835..44308
                     /locus_tag="PK679_03005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HPC54960.1"
                     /translation="MSSETIVTALFLISAVIAAGVLINAIFPAIYRTADTFGSVSTQA
                     ETKMRTDFRIVNTFANDTAVKVWCKNVGTARIHVNEIDNGDMYAGNPGNFDRWSLEGL
                     YNKGDLVNSYWDPGETLTITKTGIGSYLSGDDDVYVAIVLPNGVRRDLTFAKFSS"
     gene            44325..44804
                     /locus_tag="PK679_03010"
     CDS             44325..44804
                     /locus_tag="PK679_03010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54961.1"
                     /translation="MAAASLVATAFGIIIIIITAYVLAGSTLATSEIVTTAQKDMTEI
                     QLKMLGTSLEIGEPPVNLTSPLSITLTNTGNEPIRDFKNMEVYLFFSDTGPVLYKYSP
                     GGGDGWWNDSRSLGYFYPTQWDPGETMTMIITYSESSTPIGIQVTTPNGVSARRVLS"
     gene            44865..45611
                     /locus_tag="PK679_03015"
     CDS             44865..45611
                     /locus_tag="PK679_03015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HPC54962.1"
                     /translation="MAGSVSEGLSSLLGGEDKNILSTGNSEIDKKIADGIPLGSLTLI
                     EGENDTGKSVLTQQIMWGAMKQGLRVDLYSTELTAKSFLSQMESMSLDVSDYFAWGYI
                     RLFHLHMVGFKWTKEEMDGILQRIVNHIRQSKAEVAVIDSLTMFTEYTEQSSILSFLT
                     NCKNLVDHGKTILITLHTYAFEEDTLIRIRSICDAHLSMKKALIGDKYVMVLEVVKVR
                     GARKTTGNLVSFEVHPGYGMKIIPISMAKV"
     gene            45618..47486
                     /locus_tag="PK679_03020"
     CDS             45618..47486
                     /locus_tag="PK679_03020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system ATPase subunit"
                     /protein_id="HPC54963.1"
                     /translation="MSSLTAALTLPFKPAENTEDNDCANNIEGCALYRMLPVNAKEYV
                     KKAPHLLEYLHIFPVDEYGIPLFFSELKRDLKSMTDPNLIYPADDTVFVHIFFDPNDV
                     RNYYIPVDPSFMHSVKELLPAVEIKLVDLLDALEEDPVTDEERAEVLKRLISQVLYVR
                     KPGEQVAALPGKTNQKGFGAKLKDFLNKDLTARTNPHKTAILASVPQTPDGRIIVSPQ
                     EYRAIEYMIIRDKIDVGLLKPFINDRYIEDITVDGVGPIFVEHKIFKGLKSVVGWDNT
                     EELDNFVIKLAERTKRPITYRNPIVDATLPDGSRINIVYSTDISRKGSNFTIRKAMDD
                     PISILKLIEFKTCDYMVAAYLWICIENGMSLFMSGETASGKTTSLNALTTFIPPENKI
                     VTIEDTPELQVPHKNWTREVSKGKGKGEGEGSDVTMFDLLKAALRQRPNQILVGEIRG
                     VEGSVAFGAMQTGHPVLSTFHAASVEKLIQRLCGDPINIPKTYVDNLNIVVIQSAVKR
                     PSGETVRRMLSVNELVGFNPETQGFSFVEMFHWDPVTDTHEFTGKGSSYLLENKIATM
                     LGIPEHKKAAIYDEVEKRARILERLHKAGYTGFYDLYHMMTKIKKQGLLKIDIDSM"
     gene            47487..49085
                     /gene="flaJ"
                     /locus_tag="PK679_03025"
     CDS             47487..49085
                     /gene="flaJ"
                     /locus_tag="PK679_03025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archaellar assembly protein FlaJ"
                     /protein_id="HPC54964.1"
                     /translation="MPLTGFGEKVRQANAGKLPFQDAFSSIKERFSGLSENKRMGPDL
                     LFMVTYMASITTAQATRPEIFAYTAARKEYVPTKYIERIEFFVKRWNYSYVQALSLMA
                     DKVQNDMLRSMLHRYSNSIESGVPDEDFLTRELSTIRSVYRNAYEQGLEMLKKWSDAY
                     IAMLFSATLVGIIMMISVAIFAPDDIQQTLISSYMIVLAVSVFGLVTMYKSVPQDDKT
                     HHLGKGSREQNLIRSLERKIIPLAFMAGIILAVLTTNVGLSMLMIGLLLLPLGFIGYL
                     DDKNIIVRDSEFTTFIRSLGAVMGGKGITIGSALSEIDRKSLEALEPFINGVYSKLNL
                     GLDEKLVWQRFIYECGSNLIYKYLNIFRDSVELGGKPDIIGQIVGSSMLEQVLLREKR
                     NNVSMGFVILLIPMHAMMVGIFLFLYHIMVTMSKAIGSVISTMGSTAGSALSQPGTIS
                     GSLAGGINLFVNFPEYEMSVYTVIMISILTVSNIFAGRIVMGGDRYMYYFFGSLLLGV
                     TGIIYIVAPVIVGMFFNIPTFQGI"
     gene            49089..50255
                     /locus_tag="PK679_03030"
     CDS             49089..50255
                     /locus_tag="PK679_03030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54965.1"
                     /translation="MQESTVRVILLVVIMAFGTVMLLFPVPLFYLLLGAIALALLVLF
                     LTGTIRMPSLKRKKKSETAGPRPEKEQKVRKVKEKKEKKPKTREGGRKFPEIISSLKK
                     AFAVLGRDLKKARLSRDESPERAKKIDTLLDQTVRGEAVASLDDIVPDSVPAEKKKAE
                     DPFSALVGEDLNPDLLGEIEPPGDFSIPGDEDLGIEIPTQDFIAPDTGVQQMDLSLTS
                     DEAPIAIDETNDADEVKEILEAHKDEIGMPATTMEIPLPEEDLGGLDNLDLDGIEIEG
                     EGTSPQPAAPLSAGGGTGPAAKGPMATPAPAPPAQEQKIPASLSQPETEMLSFGTGKR
                     EDDDLMASLKSEAKVKKKSEYASLIRDLKDIKVNASDLQKELEDLLKPRKPGTR"
     gene            50276..51085
                     /locus_tag="PK679_03035"
     CDS             50276..51085
                     /locus_tag="PK679_03035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CheF family chemotaxis protein"
                     /protein_id="HPC54966.1"
                     /translation="MALVPVKIEKDGKWLVGKIDLQQDSMNVVEPFKAAIPYKSVIDL
                     EEKKNVLIITVKGDPPVIYRIASVEKVLQAMKRFIAMSCSAYRLMAYFMSPAVRGGVM
                     VTNATWEKGAIAVLKSTIWFVSQNKQVSVALKEVTSMEITKKEVQKNQVDVLKLDHME
                     NTDVVTSYVLCPLSTLQILINFLKDATKDLEITGEELDPVAAQVGMLIYSGMDSHAIE
                     KMLNIPYKNLDEIYEKLLKLGMAEVTQVRREVQLTPKGVRFITESVKPPTQ"
     gene            51159..51521
                     /locus_tag="PK679_03040"
     CDS             51159..51521
                     /locus_tag="PK679_03040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC54967.1"
                     /translation="MGRILIVDDTLFMRTLLKNILFSGGHDIVGEAGDGDEAIAKYQE
                     LKPDLVTMDVVMPKVNGIEALKGIRAIDPNAKVVMCTAVGQEQMVKLAIKTGAKGYIV
                     KPFQAPKVLEEIKNVLSS"
     gene            51526..52554
                     /gene="cheB"
                     /locus_tag="PK679_03045"
     CDS             51526..52554
                     /gene="cheB"
                     /locus_tag="PK679_03045"
                     /EC_number="3.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0008984 - protein-glutamate methylesterase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis-specific protein-glutamate
                     methyltransferase CheB"
                     /protein_id="HPC54968.1"
                     /translation="MIRVLVVDDSLFMRTMIRDMLEKDPEIEVVATAIDGVDALKKIN
                     EYAPDVMTLDIEMPRMNGLEVLKSRSKAAAFPKVLMLSSLTSEGAEMTRAAMMLGADD
                     FMLKPKDISAVRGIGKELIDKVHNLVSIAYVRRVEKPPEALADRLVVIGASAGGPPML
                     DVLLSSMDSPIPAAMVITQHMPEGGFTASLATRLNRISPMPVKETESGDVLLRGNVYI
                     SKGGYHTIIGAHVGENGVKGGRIIHSQSPPVHSVRPAVDRTFTSAATTFGDRTVSVIL
                     SGMGSDGGEGMAAIKQHGGKTIVCSEEDCLVYGMARSALSRNCVDKVIPLKQIGKEIA
                     RVVAGMVN"
     gene            52561..54528
                     /locus_tag="PK679_03050"
     CDS             52561..54528
                     /locus_tag="PK679_03050"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HPC54969.1"
                     /translation="MSELDAYRSLYIAESRENHENIVKHLLLLETEASETAIAEIFRS
                     AHSLKGMSASMDFKGMERLCHAMEDVFQEIRNGKLAVSRELMDSLLVASDQIEAMLDD
                     IECGGPGIPPNLDDLENELKRWIGKGGIRGGPESVTPPAAGDTSAPGAESPDMPAGAP
                     RYSLAIQLTDTCDNPNLRAMIILQNLEEVGTIERVIPDRSVVEDGEFGRRFEVEITSD
                     AGIDALKTIATTTDVLSATVTEGGRKTPVPASPPAPVQPMEKEDIRTAKQPEKVEKSR
                     EVKNIRVDISRLDSMMNLVEDLVINRGRITEIARGHQIKELDETLNMIGRSVSDLQAL
                     MMDIRMIPLSHIFNRFPRTVRDIANREGKEVEFIVEGGDTELDRSVMDGLNDPLLHLI
                     RNAIDHGIERPEVREAAGKPRKGTLLLSARRDRDNVIITIKDDGQGIHAEKVRKKAIE
                     KGLITPEEAQALTREEIIDFLFHPGFSTAEKITDISGRGVGLDVVRTTLESLHGTIKV
                     DSREGEGTTFELLLPPTMAIVNVMMVRINGRRCAIPIHNVVEVAGLDTGNIHTIGGRE
                     TILLRDEVMPLDRLDDMFGRSPATEILVVLQHQNRKRTIAVDEIEGQQEVVIKPLSKV
                     VGTVRGISGVTIPGDGEVVPVLDVNSIVSET"
     gene            54544..55149
                     /locus_tag="PK679_03055"
     CDS             54544..55149
                     /locus_tag="PK679_03055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HPC54970.1"
                     /translation="MLNSQQSDALRELGNIGAAHAATTLSTMLMTNIEMEVPEINVVD
                     IGKIHEHVSDEQAALVIFQIQGEVSGGGYVLLHIPKNSVVRLTNAMLGMTELDRELTE
                     MDQSALLEIGNIMVSAFLDATATLLSIVMLPSPPSLVIDMPHAAFESILAAQDYAQID
                     QVVIFRTELHSDQYKISSNLFLLPNKPMLDEIIGMLENLMK"
     gene            55157..55642
                     /locus_tag="PK679_03060"
     CDS             55157..55642
                     /locus_tag="PK679_03060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HPC54971.1"
                     /translation="MMPGPEEQVVMVGIGEYHIGRSPMSSIGLGSCIGLVIHDPVNDI
                     GGLAHIMLPDSQGRTDRPAKYADTAVEFLIRGICRQGSKPDGLVSKIVGGASMFQSFS
                     GNLNIGDRNIEAVKIQLKKFNIRIVAEDTGGIQGRTIVYYPEEKGKISVRTADGNIRF
                     I"
     gene            complement(55639..56193)
                     /locus_tag="PK679_03065"
     CDS             complement(55639..56193)
                     /locus_tag="PK679_03065"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008792 - arginine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006596 - polyamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase, pyruvoyl-dependent"
                     /protein_id="HPC54972.1"
                     /translation="MVVPSRVFFTKGVGVHRDRLASFELALRKAGIEKFNLVYVSSIF
                     PPNCKIVSVEEGCRMLEPGEITYCVMAKNDTNEPNRLISAAIGLALPKDAKEYGYLSE
                     HHAYGETAEKTGDYAEDLAATMLATTLGIEFDINKAWQEREQIYKASGKIIKTTQICQ
                     SAQGDKNGLWTTVIAAAVFITNRN"
     gene            56436..57455
                     /locus_tag="PK679_03070"
     CDS             56436..57455
                     /locus_tag="PK679_03070"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC54973.1"
                     /translation="MVNREKAGDGIIPKTGTIFTCICICALLCAIPATVRSDTPLPCK
                     FFGKVTLYGSPAPPGTIITATVNGNVRGSYTTTEWGKYASDCMFGPKLVVQPLGEDLA
                     ANDLLLITFFVNGQPADETAFYFPGATRWLDLSVTRIPTPTPTPSPTPTPAPTLTPIP
                     TPTPSPTQTPSPTPTPVPTPMPLPVAHFNCTPDFGYSPLIVFFTDLSGQNVTSWSWDF
                     GDGNTSGEQNPVHTYRHPGNYTVNLTIESDTGYSSSIIPDCVVVLAPSLIPFPEQENL
                     PGDPDDDGYYEDLNGNGRTDFDDVVLYFSYIDWISENITSNPFDYNQNGRLDFDDLSC
                     LFLEV"
     gene            57609..58664
                     /gene="carA"
                     /locus_tag="PK679_03075"
     CDS             57609..58664
                     /gene="carA"
                     /locus_tag="PK679_03075"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HPC54974.1"
                     /translation="MKAVLGLEDGTCVAGKGFGVEGECAGELVFSTQMSGYMEALTDP
                     SYHGQILMFTFPTIGNYGVDRANFQAERVWARGCVVREVCDVPEVPPSLSTFFAENHL
                     LGIQGVDTRMLTIKTRVEGTLRAGLVVGNDDSERAVELAQKTPPLSQVDLIPDVSCRQ
                     PYHIPGKGKRIAFIDLGLKKNMLVSLRHRDADIFVYPHDCTPDRVLESKPDALFISNG
                     PGDPVLATHAIRCVKELAGTLPIYGICMGNQICALGLGAKTYKMKFGHRGTNQPVRYK
                     DGSIYITTQNHGYAVDADTLPEGSYPIYTNVNDGTLEGFEDPYLDITCVQFHPEAHGG
                     PRDTEIPFFDTMFRRLS"
     gene            58664..61831
                     /gene="carB"
                     /locus_tag="PK679_03080"
     CDS             58664..61831
                     /gene="carB"
                     /locus_tag="PK679_03080"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HPC54975.1"
                     /translation="MPKKAHIRKVLLIGSGPIQIGQAAEFDFSGSQACRALREEGVRV
                     VLVNSNPATIQTDPEMADEIYIEPIKADIIEKIIRKEKPDGILSGMGGQTGLNMTAEL
                     AERGALKGVEILGTPLEAIYQGEDREKFRALMERIGEPVPRSMILNRPDQVEEALRTV
                     GLPAIIRPAYTLGGSGGGIAHTREELTRIIEIGLTRSRIHQVLVEESVVGWKEIEFEV
                     MRDAGDTCIIVCGMENVDAMGIHTGESVVVAPILTLRDDEFQTLRTAAIKIIRALDVQ
                     GGCNIQFAYRDGEYRVIEVNPRVSRSSALASKATGYPIARVAAKIAIGLRLDEITNSV
                     TGCTPASFEPAIDYIVVKVPRWPFDKFRNADRTLTTAMKSTGEVMAIGRTVEEAFKKA
                     LRSLDTDMETHTSPPEIRMILSRPTDERFHTLFDAVRAGFSVAEISEMTHISPFFIEK
                     VKNIVDMEKRLRESAGKDEILLARRYGFSASEIASLTGLSPDRVREIAGDPTYKIVDT
                     CAAEFPARTPYFYSTWDTECEIPRTERQKVLILGSGPIRIGQGIEFDYCTVHAVKALR
                     EEKVEVHIVNNNPETVSTDFDTSDRLFFEPMTLEDIINILQKDTYMGVMVQFGGQNAV
                     NLAVPLQEEMRRLGLATRVLGTSPDSMDIAEDRDRFSILLDRLGIPSPPNSSAYSLEE
                     AREKAAAIGYPVLVRPSYVLGGRAMEIIHDEIELEGYMKEAVRVSRNHPVLIDSFLQN
                     AIELDVDAVCDGSEVLIGGIMEHIEEAGVHSGDSACVIPTQSLSPSIIETVKEYTRKI
                     ALALGVVGLINIQLAVKDGVVYVLEANPRASRTVPFVSKATGIPLAKIAAKVMIGKKI
                     RDLGYVEKPFSHVAVKEVLLPFNKLPGVDTVLGPEMKSTGEVMGIDYDFGRAYYKACV
                     SADNTLPLEGNIFISISKDQKDEVIPIARKLHEIGLRLFGTAGTVEYLNDAGIPAQHV
                     RKVQEGSPNAIDLLRRGEIRLIINTPTDKQSRQDHYQIMRAAVDYGVPYITTIQAARA
                     ATMAIEAMRKEQITIEPLSHYIGEM"
     gene            61973..63166
                     /locus_tag="PK679_03085"
     CDS             61973..63166
                     /locus_tag="PK679_03085"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HPC54976.1"
                     /translation="MGKGTVVLAYSGGLDTSICIPLLRERYGYDRVVTVAVNVGQRDE
                     EITTATEKGHKLADKHYTIDAREKFVTGYILPAIRANGSYEGYPMGTALARPLIAEEV
                     VKVAAREGAHAVAHGCTGKGNDQLRFDFIFRMAGLDVIAPIRELNLTRDWEIDYARDH
                     GIPVPVGKERPWSVDENIWSRSIEGGMLEDPACHPPEEIYAWTVSPVNAPDKPEILAI
                     DFIKGIPHRLNDVEYAPFDLIRELNTRAGRHGIGRNNMIEDRILGLKAREIYEHPAAT
                     VLLLAHHDLEHLTLTRQELAFKHVVDEKWSELAYMGLVHEPLFHDLSAFITQSQERVT
                     GRVEVQMFKGCCRVLGRSSPEGLYSGDLVSFDTTSIDQCHAIGVSAYYGIQARLAEQG
                     KKGRK"
     gene            complement(63373..63777)
                     /locus_tag="PK679_03090"
     CDS             complement(63373..63777)
                     /locus_tag="PK679_03090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HPC54977.1"
                     /translation="MVNLTPEMKETFAKIKLFPVATASKKGVPNVAPIAFVIMAADDT
                     LWLADNFMHKTLANVKENPHAAIYIWDPDAKKCFQIKGTVEVKTSGPDYEKMKKMVHE
                     KKPDLPAKSLLVMKITEVYECNPGPHAGKKLL"
     gene            63927..64874
                     /locus_tag="PK679_03095"
     CDS             63927..64874
                     /locus_tag="PK679_03095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC54978.1"
                     /translation="MAGTRECEPSYLSLHRSGELDRRVERIRELLSPCRVCPRRCGVE
                     RIRGETGYCGGGLLPKISSYGPHFGEEPPLVGVYGSGTIFFAGCSLRCAFCQNYEISQ
                     ERYGREVSCEELAQIMLRLQDRGCHNINFVTPTHFVPQIVRSVSIAVKQGLALPLVYN
                     TGTYDSVETLRLLDGIFDIYMPDAKYADNDIAIALSDAPRYVNVMEEAILEMQRQAGD
                     LVMDRGIARRGLIIRHLVLPGDLAGSGRILAFIAEKVSRDAYVNIMDQYRPCGRVGDL
                     GADPRFAVLNRRLTAGEYERAVSAARRAGLHRGIPLGNS"
     gene            complement(64885..64956)
                     /locus_tag="PK679_03100"
     tRNA            complement(64885..64956)
                     /locus_tag="PK679_03100"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(64921..64923),aa:Arg,seq:gcg)
     gene            65557..66615
                     /gene="gmd"
                     /locus_tag="PK679_03105"
     CDS             65557..66615
                     /gene="gmd"
                     /locus_tag="PK679_03105"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HPC54979.1"
                     /translation="MKKALITGITGQDGSYLAELLLSKGYEVHGLVRRSSSLNTSRIS
                     HIFPEAEIAGTASSGSGLFLHYGDLSDSEQVSTIMDRVRPDEIYNLAAQSHVRVSFDT
                     PEYTGNITGLGTTRLLEAARRSNPGVRFYQASSSEMFGGSPPPQNENTAFYPRSPYAC
                     AKVYSYWMTRNYREGYGMFACNGILFNHESPRRGETFVTRKITRGIAKILAGKEKMLA
                     LGNLDAKRDWGYSPEYVECMWLILQQEKPDDFVIGTGETHSVQEFVDAAFRYAGLDRD
                     EHVTIDQKYFRPTEVDVLVADPRKAEKKLGWKARVRFGDLVKIMVDADMRAFGLEPIG
                     EGDRIVEKRFGEKWWKGD"
     gene            complement(66635..67645)
                     /locus_tag="PK679_03110"
     CDS             complement(66635..67645)
                     /locus_tag="PK679_03110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011450018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HPC54980.1"
                     /translation="MKDYSKDLERILDDRELHDFNSQRVLITGGAGFLGSWLCEAFLR
                     LGASVTCIDNFASGREENIRHLKKDPGFSFLYQDVSAPFNPDGGYDYILALASRASPL
                     EFADHPIDILRSNTLGTMNALEIARKNGATLLFTSTSEVYGDASVFPTPESHNGNVNP
                     VGIRGCYDEAKRAGEALCMAYYRQYGTDARIVRIFNTYGPRMRSDGIYGRVIPRFITQ
                     AMQGEPFSIFGDGLQTRSFCYVTDQVRGLIRFISRPGLAGNIINIGNPEEVSILDLAR
                     CIAEIHGSEPRFEYHPQPPDDPRRRLPDITKARKVLGWTPEVPLKEGLEKMIHWCRDT
                     PS"
     gene            complement(67652..68533)
                     /gene="galU"
                     /locus_tag="PK679_03115"
     CDS             complement(67652..68533)
                     /gene="galU"
                     /locus_tag="PK679_03115"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011450017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HPC54981.1"
                     /translation="MTQRSRKVKKAVIPAAGLGTRFLPATKVQPKEMLPVVDKPVIQY
                     VVEEAVSSGIDDILIITGRGKRAIEDHFDTSFELEAHLAEKKNHSHLKEVRDLSGIAD
                     IHYIRQSHPRGLGDAILHAQKHCDGEPFAVLLGDTITIPHAGQPECTTQMVQAFGKYE
                     STIIVVEEVPPEKIRDYGIIDGHRISDNAYAITDIVEKPLPENAPSNLGAIGRYILTP
                     DIFDILKNTRPGYNGEVQLTDALRRVDNPIGLVTHCTRYDIGDKMGWLKTIIELSLQR
                     DEFADELAAFMKQLVRD"
     gene            complement(68669..69934)
                     /locus_tag="PK679_03120"
     CDS             complement(68669..69934)
                     /locus_tag="PK679_03120"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR03026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HPC54982.1"
                     /translation="MRVCVIGGGYVGLVTGSCLAELGHNVVIIDIDEKKVLSINEGKP
                     PLFEAGLEEIVKKHIGKNLSATCSFFPVKDAELTMICVGTPPDNSGNADLHYVRSASE
                     SVGRALRNQDKKHYVVVKSTVPPGTTDGLVRETVLSEAGRENIAFGMNPEFLREGRAV
                     WDFFHPDRIVIGCHEQDLFDCMKRLYQGIEAPVIQVLPTEAEMIKYVSNAFLATKISF
                     SNEIGNICKRMGIDVYRVMEGVGLDRRIGKEFFNAGVGFGGSCFPKDVMALARFAEGM
                     GVEPCILKSVLSVNEDQPGKMISLLEKRVGGLHGKRIAVLGLAFKDNTDDIRESRAIP
                     VIRMLRERGAHVAAYDPLAIPAMKEVFPDIDYGTTPEAVLEGADACLILTEWPEFSRL
                     DKEFDLMNNRVIIEGRRVLKTHGYEGICW"
BASE COUNT        15318 a        20538 c        19520 g        14525 t
ORIGIN      
        1 atggactctt tgagaatatc tgcatcaatc gttgctttta acatcgtaca ccccgaatat
       61 gtagtattat aactatccca tcaacgtttt aataatatct ccatttgtcc cggaggatcg
      121 gggctcattg aggagtgcca tgggttcaca gtggggcagg gattcggcat acgtgcgggc
      181 gatccgcgaa ggatacaggt cgagggcggc ctacaagctg aaggagatcc aggaaaggtt
      241 ccacctcatc cgggatacgg acaacgtcct cgaccttggg gccgccccgg ggagctggct
      301 ccaggtcacc cgcagtatca cgaagggcag ggtacttgga atcgatcttg cacccatcgc
      361 tccgctggag ggggtaacca ccctcgttgg ggatatcacg gatccccgga tgcgcatgga
      421 ggcccgatcg atcctcggga cggtcaacat cgtactctcc gacgcatccc ccaagctctc
      481 cggtaacagg agttatgatc aggcaagggc aatcggcctt ggagaagacg tgctttcgtt
      541 tgcgtgtgcc gtcctcaaac ccgggggaaa cctcctgatg aaatccttcc agggagagga
      601 tttttcgggt ctcctcgacg acgtgaggca gcatttcctc tcggtaaaga cattccggag
      661 ccgggcttcc cggaagggga gcagcgagat ctacatcatt gccaggaact tcgtggagtg
      721 ccatggtgag gctgaaggac ccgtttgacc ggccggtcag taacctgcgg gtgagcctga
      781 cctcacggtg taacctctcg tgtatctact gccatgccga aggggaggag cgtcccggag
      841 accagctttc ctgtagcgag atcgccgaga tcctccgcgt ggccgataga ttcgagatca
      901 ggcacgtgaa gttcacggga ggagagccat gcttaaggga ggacctcgcg gaaatcgtca
      961 gcctcgtccc tgataagatg gagtgttccc tgaccacgaa cggaacgctc cttgcagaca
     1021 tggcagggga ccttgccgat gccgggctct cgcgggtcaa tatcagcatc gacagcctga
     1081 acagggaaac gtacacgaaa atcgccggta aagactgcct ttccgatgtc ctggccggaa
     1141 tcgaggccgc actcgatgca aaactggtac cggtcaagct gaacatggtg gtcctctccg
     1201 gcatcaacga tcacgaggtt gatgacttcg tccggttcgt gaggggcaac aggaacctcg
     1261 tcctccaatt aatcgagctc ctcgggttcc gcgattgcga ccaccattac aacctccgtg
     1321 acctggagac gagattcgca aagaatgcaa gggagatctt tacccgccgc atgcaccacc
     1381 gcaggaaata ctgcgttgac aatgcagagg tcgagatcgt cagaccactc cataacacgg
     1441 agttctgtgc ctattgcaac aggctccgcg tgacttccga cgggaagctg aaaccgtgcc
     1501 tgttgcgctc cgacaacctt gtcgacatcc gcggtgcttc gggtgaaaaa ctcgaggaac
     1561 tcttccgcga agcggtccgg cggagggccc cctactaccg gtgacagggt acccgatata
     1621 acccctatat cctctcaatt tcgaaaaatg ccatttccgg aaggtattta ctgcggggaa
     1681 cccgatctct ttccatgaac gccgatgaag aatacgtccg ggttctcgag cacctttatg
     1741 aaaagtccct ggtgctgcac gatacgtcgc tgtgggatcc agtcctgcat ttctttttcc
     1801 tcgacgccct cgcccacctt gactatactt taggtatcct ctcctacacc taccagtcac
     1861 cgaaaaacat catggcacag gaatacatgc gctggaggat cgatgaagaa aagaagggta
     1921 accgccagca ctttcccgcg ttcatgtcct ggcttgcaaa gaaccacccc gacaggtaca
     1981 cccgcctgcc gactctctgg cagcggatct acgaccccga tgaccctgca tcctaccgga
     2041 gtttccggat agtgctcgat ccggactccc agcaggtgat aaagccgcac gtgttcttcc
     2101 gcatgataga cgagttcttt gacagggaat tcctaaagag cctctatagc gaggacgggt
     2161 cgctttcaag actctttgcc gagtttatga aggaacgcag gtcgatgtcg gttccgggaa
     2221 actaaaagga tatggggata gctgatctct gtgcaacgct cgtgaggata aagagcgaga
     2281 acccgccggg tgatacgcgc gacgtcatcg agtacatcag ggacttctgc tctggtatcg
     2341 gactcgggat gaaggtcgtg aagaggcgtg ggggcaggca caacctcgtt tctgcgaaac
     2401 cgagaggaaa gctcctcttc tgtggtcatg tcgactgcgt gccggcgctt ccggacgggt
     2461 ggtcggatga cccctatggt gggactatcc gcgacgggaa ggtctttggc aggggaacga
     2521 ccgacatgaa gggaggttgt gccgcagtcc tctgggcctg cagggaatgg atggaaagtg
     2581 ggcgtgatct cccggcagat ctggcttttg tctgcgatga ggagacaagc ggaacttacg
     2641 ggatccggac tctccttgca aggagggcaa taattccctg cgactgtatt atcgcagaac
     2701 ccaccccccc cttctctcca aacgtggggc agaaggggat catgcgtctc tgctgcacgt
     2761 tccgcggcga accggggcat ggatcgctct accccgagaa aggtgtcagt gcgatcatgg
     2821 aggcgtatag gttgctcgac ttcgtaaaag acctccacgg tgtctccttt aaccccgggg
     2881 atcccggcct ctccggcctg atcagggact ctgcagccat cctcggggat ctcctcgata
     2941 tccccaacgc atacgatatc ctgacacggg tgatgtacaa ccccgggacg atacaggggg
     3001 gagagaaggc aaacatcgtt gcacagcagt gcaggctcga actcgacctc cggattccct
     3061 gggggtgcaa tttggaatct ctcctttgcg acctgaaaag gcatgccccg cgtggcgaca
     3121 tagcggttac gaacatggcc gagccgagcc ttacgccacc ggacgctccc ctcgtgtcca
     3181 ccctcctgca ggagatagag aaggtataca aaagaccggc acggcccgtc gttcaatggg
     3241 cggcaagcga tgcacgttac ctccggaaag aaggtttttc tgtcgtggaa tacggtcccg
     3301 gcgagatccg cacgcttcat gccatcgatg aatatgtcac aatcgaatca ctcgtgaatg
     3361 catcgagggt ctacaggggg atgctcgcgc actatgcagg agcgaaaaaa agggtctctt
     3421 ccctttctct cggcaggtcc gtttcgtaag cattctgcgg tcttagaaaa aaatcacaat
     3481 ttgaataata atttccaatc gggaatcatt ccttggtcat tttggtattt tgtgaggatt
     3541 taatctatcc tgtgcacacc actaaatccg ggtgagagaa aatgcccaat ggtggaccag
     3601 gaatgggaag gatgcggagg ggggttcccc ccgggtcctg tatctgccca aagtgcggga
     3661 aagaatttcc gaaaacgcgg ggtacgccat gcaggaacca gacctgtcct gaatgcaatg
     3721 taccccttgt cgggaagtga catttgccca atttacgtga attggcaaaa gcttccccat
     3781 ttttaagcct gactacccct tacttaagag gcagggttta tacctgtcgt atctgcatcc
     3841 tctttttcat ccggtcatac aacgcgagaa gtgccccgag aaagacggga tacaggaggt
     3901 ccatgtacat gaccgggcct gcattgttta tagaggcatt gccgtgcacg acgagctcgt
     3961 aaacatggcc gatacctgcc ccgattgaga atattccgaa cgctattacg gtcgccaacc
     4021 aaaaacccat cgggcgtacc ttcagacaga ggagacccgt caccccgatc gagaggtccc
     4081 agagtccgac ctcgcgctgg aaggggctgc ccgccggcca tccgatggac atcgccaccc
     4141 ggtcgggaaa gacgaggtgt ccaaaacccg cataaacata ggacaggccg aggccaactg
     4201 ccagctgcca tgcaaggaac gtttccattg ccgctatgcc ggtgaggtgt ttccacctga
     4261 tgtgaacgat tgcaacggca gcgccgacga gcgggaagaa aaacgaccag ataacctcca
     4321 tgagtgccat gaaaaagaat ttcgttctct gttcccaaaa atcataacgt tcccaccgga
     4381 ttggaaacat ccggaatgag gtttaccggg gcttttttta aaaaagagag agccacagtc
     4441 aggagttgcg gagcatgcgg tcaatcgccc gcgccgccct ctttgccccg cccatcgcga
     4501 ggatcactgt cgccgcaccc gtggcaatgt caccggcggc aaagactttc cccagatcgg
     4561 tcctgccttc ctcgtccacg atgacgtttc ccctcctgcc agttctgata cccgggagca
     4621 tcctgacgag gagggggttt ggcccctgcc cgattgcctg gatgcacatg tccgcatcga
     4681 tgacaaaacg ggaaccctcc accggtaccg gctcgggtcg cccggaagca tctgtcgcgc
     4741 acatctccat gcgttcgcac tcgactcccg tgacgcactg ctccccaagg atgcggacgg
     4801 ggctggcaca gaagacaaag gtgacaccct cctcctctgc ccttgcaatc tcggccctgc
     4861 gtgcaggaag gtcttccttc ctcctccggt agacaagtgt cgtcctggcg ccgagccggc
     4921 gggccacccg ggccgcgtcc attgccacgt ttccccctcc gaccaccacg actctccctg
     4981 cgtgtcgtac gggtgtatcg aattccggga accggtccgc gtgcatcagg ttcacgcgtg
     5041 tgaggaactc gtttgccgaa taaacaccgt tgaggttttc cccggggata cccatgaagt
     5101 gcggcaggcc tgccccgcaa cccaggaaga ctgcatcata ggagaggagt tcactgaccg
     5161 gcacgctcgt cccgacgagg tggttcgtca ggatggtgac gcccattcct ctcagctggt
     5221 cgatttctgc ccgcacgacc tccttcggga ggcggaacgc ggggatcccg tacatgagaa
     5281 ccccgcccgg ttcgtggagt gactcgaaga gaacgaccga atgcccgagt cgtgccagct
     5341 ccgccgccgc agtcagtccc gcaggccccg agccgacgac tgcaaccttc tttcccgtcg
     5401 gttctgcttt cgggggcaac cgcgaacccg ttttccgctc atggtcggcg acgaaccgtt
     5461 cgagctctcc gatgcggacc gggacctcct tgagaccgag gatgcattgc ccctcgcact
     5521 ggacttcctg gggacagacc ctcccgcaaa tcgcggggag gagattgttc tccttgatga
     5581 cctgtgcagc ccccgcaaag tccccttcag caatgcgggc aatgaaggca ggtatgtcaa
     5641 tttcaaccgg gcagcccttc acgcacgatg gtttcttgca ctggaggcac ctttgtgcct
     5701 cggcaaccgc ttcttcggca gaaaggcccg tatccacctc ggaaaagtcc ctgacacgct
     5761 catcggccgg tcgttcaccc atggtggtcc ctcccgccgc acccgcagtg gtgcgatgag
     5821 aatctctcga gcgcgagctt ttcctcctcg aggtacgtct tttgccgtgc catcagggtg
     5881 tcgaagtcca ccttgtgggc atcgaactcg gggccgtcaa cgcaggcaaa ccgggtctct
     5941 ccacccacca caaccctgca ggaaccacac attcccgtcc cgtcaaccat gatcgggttg
     6001 agggagacga gcgtggggat gccggcagcg cgggtcactt ctgatgtcac cttcatcatg
     6061 atcgcagggc cgatgatcca gacccggtcc ggtctctctt tcccgatgac ctgtttcagg
     6121 acgtccgctg caaacccatg gtgacccttt gtcccgtcat ccgttgcaac gaaaagttca
     6181 tcgcaggttt cccccatttc ctcctcgaga atgaggaaac ctgcgcttct tgcaccgatt
     6241 atccccgtga ccctgtttcc tgcggccttt gcggcccgtg caatgatcgg gcagcacgca
     6301 atccctgcgc ccccgcccac gatgacacag tgcccgaaat gtccaatttc gctcggtttc
     6361 ccaaggggcc cggcaacatc ccttatctcg tcaccggcca caagcgttgc aagctggtac
     6421 gtcgtcttcc cgacggccat gaatatgacc cgcacaaggt cacccttcac ggcagatatc
     6481 gtgaggggaa tacgctcccc cttctcgtca atcctgataa cgaggaactg gcccgcacgt
     6541 gcattccggg ccacgtgggg cgcctcgatc cagatctggt aaatgcgctc ggccatcggg
     6601 ctggcctcct tcacccggta tcccacgatt tcgtcctcac cctgccgcga gaagtgcagt
     6661 gtcatacatg tttcccgccg ggggtcttta ccttacgcac ctttgctgca acacccctgc
     6721 gggatcgcac catctcggga cccggcatcg ccgcacgtcc cgtggcgacc gcaagaggac
     6781 cggtcacaaa tacctcgtct ccctccctga tccggggatc ggcgccaact acacccggcg
     6841 caaggatatc gcccgatggg acgaatgaat cgatctcaac ccggtacccc gcggggatga
     6901 gttcccagcc cccgaatgtc ggacggagaa gccctgtccc gggatcgagc gagaagagcg
     6961 gttccatgcc cctgaatact ttcaggtcgg ggaacctttc cttcagggtg aagcctttcg
     7021 tgtccacggc agtatcgaac tggtaagaag cagttgccct gacgagatcg tgggtgacag
     7081 gtttttcccc ggataaagcc ccggaaaggg cattgagtgc cgcgcgcgat gtcgccctgt
     7141 caccacccgt ggtgcactcg aggtctatgg atgccatctc tgcagccatg cccgctgcat
     7201 cgagtgcccc gccttcgagg tgggcaatga cacggcggaa ccggtgtttc ctgaagaatt
     7261 gcgcaatcac tcctgcgatc caggccttct cctccgcgtc ccagtacccc gttacgggga
     7321 catcgtagtg ggcagccggg tagacacgct cgagatccct cggaacgaga ccgagcggtg
     7381 acgtcacgat gagctcgaga gccctgccgg ataccgcttc catgaacctg cggtgactct
     7441 gcgagaggaa atagggcttt tttgcagagc aggggagaag gacagcgaca tccgcggcag
     7501 gcgggatgta gcggttgaca acgcggtcag caaaacgccg gacctcggtc ctgaagagtg
     7561 actcgccact cgttgcgagg aaagtcccgg gccgggatac cggaatgcgc ggttcaagga
     7621 aatgactctc ccggtccagg aacctgatga tcgagacgta ccgtgaatcc atccgtgacc
     7681 ggctctcgac gaggtcccgc aatgacgagg acgcgatgtg catgcggacg agagcgagct
     7741 cgcgcaggag tgctgccctg ttgtgcctga ggaggtcccc ctccctgcag cccgggcagg
     7801 aacatgcgcc ttcttccatg aggtctgccg gaaagacacc ctcggggagg cagaactctc
     7861 cccttgccga cgcaaggtcg acagcggtga agtcgaagag gtcaaacccc gtgtagcaga
     7921 ggagcgagat gttcgacggg acggcggcag ccggggcata gaaggctgta tcgggaggga
     7981 ggcgctcttt cagccgtacg agccactcga catatttccg ggggtcagcg agggctgtat
     8041 gccagcaggg aaccatgacg caggtccctg acccgacatc cctgtcgact gccgggtgga
     8101 ccctgactgg cagcgtctcg cctgcgggga ggtacctcgc tgcaaatccg ggatctgcat
     8161 cgaggggtac gttttccagg ctcgacccgg ccagtccggg aaagagggtg tccgcttccc
     8221 cggcagaggg aaggactata tcccggccct ccacggaaag atgcgaaatc cgtgcaagcc
     8281 cgtccctcct gataacctca aagcggctca agggatcacc tgcacacccg ggagctcgct
     8341 catgagcagg tcccgccatt caagcgggca ggtgacagag aattccgtct ccggatggga
     8401 ctccatcagc accctcatgc cccggcagcc tgcagagacc atctcattgt cccagcaagg
     8461 gagctcacat tgccctatgg gaaacgtctc gcagagcgca gggtggtagg gaccaaatgg
     8521 aggtttgaaa aagagcgtca ggtcaaagcc ctccctgccg gtaccgtcga gggagatcac
     8581 cacccgggaa gggaggtcga gacgttgtag gagcgcgtgg taacggatga cttcggtgcg
     8641 caggcagctc tcctgccccc tgtagaagaa cctccgcttg cttaccctgt ccctcttttc
     8701 gagggcctcg ccgtgccgga ggaacgccct gtacccgtcg aggaggagtg ggtggctcct
     8761 gcaccgctcg tccacgagtt cgaaaagaac gccgtcggcg attgcctgcc tgacgcgtgc
     8821 gatctcggca aggcttactg acaggttatg gatggcaagg agcctctctg actcttccga
     8881 ctgccgaagt tcttccgccg tgtggctgcg gcaaacgtgg caggcgcacg gaagttcacc
     8941 catctcctgg agtttcgcac ttcccgaggg ggtgagatag cgcccctccc gtgcgtacag
     9001 ggcatatgcg gcagaatcga agacgtcaca tcccatggca accgcgagcg cgaacatgga
     9061 cggatgaccc gcgccaaaga ggtggacaca ggaagaggac gggatcccct tctttgcagc
     9121 catcacaacc tgcacgagtt ccctgtaacg gtacgattcc atgagaggga cgaccgcacc
     9181 gatggggcag aaggaaaaac ccatctctcc gacggacctt cctgccctct cgcggaggtc
     9241 aggaaagatc cctccctgta ccgggcctgc aacgttattc ctctccccgc acagggcaag
     9301 ggcctccccg aggcgtgaca tggtgaccga aaggtctctt tctgcggtcg ccctgtctgc
     9361 cgatggcggc gtggggatat cgaggggaac gatgatgtca ctcccgatat cctgctggaa
     9421 ccggatgacc tccccgttgg taagggagat gtcaccgtag acagagagct ggaatgcccc
     9481 cgagtctgtc atgatcagcc catcgaaccc gagcacctcg tggagaccgg acgcaagggc
     9541 ccggtcccgg aattcctcac tccgcgaaaa aatgtatgcg ttcgtgatga gtccctcggc
     9601 accgagggct ttcatctcct tcggaagaac cggctggagg tgcgggttga ccacagggag
     9661 gaggatcggg gtccggacga ccctctcccc caccttcagc ctgcctgtcc gccctgcgat
     9721 atcttcctcg aggatttcaa aaagaatgac catggtcgcc ggtatctccc gtctttttta
     9781 ggtttctatc cttccgggat accctggaat ctctccattt ccccgtacct ttcgtttccc
     9841 atcagaggtg tcccctgccc ggcaacctgt cctcttattc cccgaatatc tgcccttcga
     9901 acgtgtagac ctcaaccctc tcgtctttcc agcaacccct cgcaagaccg gccttcaggc
     9961 acgtgtggtc aaggaactct ggtgcgtccc agccccactc gagggggacc tgcgggagga
    10021 ggagcccgga acgtcccatg ccccggacga tcagcccgtg ggtgccgacc atgatattcc
    10081 gtgggcgctc ggacgccctg caggtcaggg ggacggggac tgacaggacc gtgacctcaa
    10141 tgcggatttc ggggagttcc ccggcacgca gcgggggaaa ccgcggatct tcaagggctg
    10201 ctgccagggc tgccccggag atcgcctggc ccaggggata gacaggtgtc ggaaagccga
    10261 tgcacccgcg cagttccccc cttttcttca gggtgacaaa gacaccacgt ttttccgaaa
    10321 agaccggcgg cagggcggga tagtccacgt gctttctccc gatcttttcc tcgagaacag
    10381 cgcgggcgag ctggaccgcg acccgcccct cttccggggt gagcacttcc atcaggtgta
    10441 tataatgtgc cgctgaatta tatagggaga gggagagtgc ggccgacggt ggcagattct
    10501 gccgctgagg aaagtccccc cacctgctga gcgcgcagcc gttacgcaag tacgggtggc
    10561 gagagtcacg gcaatggcac agaaacgata cggcctgccc ctggcaatga cgcgattgaa
    10621 ccccgaatcc ggggtaaccc ggggaggttc cgggattgga tctttccctg gtcgctgacg
    10681 cagaagggca ggacacggtg aaacggcgaa tccctgcggg tgcaagccag aacagggcac
    10741 atgggctgct cagttgcccg cccgggtatg gcgcatgagc tgaatgccgc atcgaacaga
    10801 agggggctta ctcctcccac tccgatatac ctttcctgca gtagatttat ccatcagtat
    10861 gcaccagggt aataccaccc atgcatgtcc ccacacctga agagatacgg gcaagaaggg
    10921 aactcctcgg gatgaaacag gccgatctcg cagagaaggc cggtatcagc cagtcgatgg
    10981 tcgcccggat cgagagggga agtgttgatc cgcgggtaag cacattgaga aagatcgtgg
    11041 gcgtcctcaa tgcgatggaa aagccgcggg tcacggccgc ccgcgtcatg cacaccccgg
    11101 tcatatgcgt tggcatcgat gaccccatca cccgtgcagc agacatcatg gaaaaacacg
    11161 ggatatccca ggtgcccgtc cttgaggggg ggatacctgt cggatgcatc tccgagtcgg
    11221 ctatcctgag cgccatcaat aacagggcaa cccatcgggc accgggtgat caggtcaggt
    11281 attacatgga atcagggttc cccaccgtcc cgaaggacac cgacatagag accgtgatac
    11341 ggatactcga gcaccaccat gccgtgcttg tcatggacgg gggcagggtc gcgggcgtca
    11401 tcacgacaca tgacttgatc tcgctcgtcc ggaaccacta gagccgcgat acgaggtcac
    11461 gcaggacggc aatcggggct ttggccttca ccacgcccga tgcgaggaga acgccgtctg
    11521 tgccgagatc gatggctgtc ttcacgcact cgccggagtg gataccggcc cctgtcagga
    11581 tacgaacgga ggggttgacc ttcctgactg cctcgaccgt gcccgtgatg atgccgggat
    11641 tggcagagga gacagagacg tttcccccga tcagctcggg cggctcgatt gccacgaagt
    11701 ccgggccgag ggctgctgca gctgcgcttg tcgcaacatt gttcgtgcag acgacggaaa
    11761 caaggtctgc ctcccggagc cgggacacga ctgcctcgat gtctgcaagg gtcaggcggc
    11821 gttccgagtg gtttacgagc gaaccggtgg ccccggcctc cctgatcgcc tcgaccgtga
    11881 cggcacccgt gttcgcaccg ggcagggctg catcgacgtg ctgggagtag accggcaggg
    11941 agtagtgcat ggagagcggg tggatgttca tgtagctggg ggcgatgccg atttccaccc
    12001 cggactcttc cgcgacctgc tgggctgcac ccgcgatgga atgtgcccgc tggccgctcg
    12061 cttccatgta tgtcttgagg ttgatgagga tgaaaggttt tggcatggga gatctcctgc
    12121 acgggatatg tatggagcca acaggggaaa acatatgctg acagggcttt catcccttca
    12181 aaaggatgat cgcacgaaat tgcccccggt cagcccgccc ctcgcaaccc gccggatcct
    12241 ctccttgaga ggctcgagcg ttcccgggtc atttttcccg gcatggcaga gttcggccgc
    12301 tctcctgtaa gcaggaacca cctcgtgtat gtattcggga cccctgcgcc gcgcatcgat
    12361 ggcaagggac cggacacccg caccgatcag gaacgggacg tggtcgatga gagttgtctc
    12421 cacggcattg aggattctcg tccgtcccag cctgtcctcg tagaccggaa aaacgcgccc
    12481 ggtttcgtct ttgagtccat agtgaccggg tccatgctcc ccgaggaggt ctgtcaggag
    12541 cctgtttctg ctcaccatcg cctcgatgtt gccctggcag atcacctcga acgaaaggcc
    12601 gggacacttt gttaccgccc tcgatatgag gaccggtata tcggcacgcg gaatttccgg
    12661 cgagagggtg aacctgtcga tgggtggatg gagaaagagc gctgcttccg aattgacgat
    12721 gttgagcccg ggtcccccga gcacctccat ttccgggacg cgtgcacgga ttgcctccgc
    12781 aagccccgtc tctccggcca tgataccggg aactcccctg acgaagaggt cagggagcct
    12841 gtcgagttct ttcctgacga acgcaggggg tgccacccgg ggccacatcc acgcaaagtg
    12901 aacccctgcc tccctgcacg tgcgggcccc ctcgaggacc tcgccggacc agtcatcccc
    12961 gccgtccccg gcggtgggtt cgaaacggac agcatcggat ccacatgtgc acgccgcctc
    13021 cagttccccg ggtgttgcac agtagaccgt gatgatgggc cgcgcattct cctccatgac
    13081 acgggcatat cctgcctggt gcgtcgccat atcctgtatc actgcagcga cagcagatcg
    13141 ggccgccccg agttccgggg gaaggggatg gaacgcagcg atccattccc tttccaggcg
    13201 atccaggatc tccctccgga cgctgttgag ggaagagagc gggaggaatg catctttccc
    13261 catcgacaca gagatgtgtc cccatacaaa gggcgaatct cccgtttttc caagctgtga
    13321 ccggactgtt cccggggaaa gcggctgcgt tcgcgcgggg acagggacct cccctgcaga
    13381 tccctcgatc gcgattcgtc ccctgacggg atgatgcacc gatgccttcc atctgacagg
    13441 ttccccggtg ctgatcgcaa catcgagatc gaccggtaca gggcggcgca tcctcccttc
    13501 ccctgtgaca gccttcatat tctccctcga agacctgctc cgcgtgaggt agacgaggtc
    13561 tcccggcctg gcaccccgca caggagccgg aaggaagagt tccccctccc gcctgctgcc
    13621 accggttttg agtgaaaaac ccccgcgtgc ctctccaccg ggggacgcta cgagaatgcc
    13681 gtctcctgca gcaggaagga tctgcgccgc cgccccgatg atgagcccct tttcgggaac
    13741 gaccgcgcgg actgtcccga gaaggagtcc ccggttgccc ggggcttcgc gacccatgag
    13801 aacgggatcc ccaaggataa aaccccccgt aaaacccctg ctgaacacaa gggccattgc
    13861 ctcttcgtct tcaggccggt aatgtgcatt cccgtttcgc aatgcatcga gtgccctgcg
    13921 gtatgcccgg acaacgatgg caacgtacgc aggagaccgc atcctgcctt cgatcttcaa
    13981 ggcagcaatt tcccgctgga aaagccggtc gagtcccgga taacagcaca ggtcgcgcgt
    14041 cgagaggagg taccgttccc tggtccggag gaccgggtat ccctgcccgc tatcgccctt
    14101 ccggggcccc atttccacca gcacgtatgg tttcctgcag ggctgtgcgc acatacccct
    14161 gtttccgctc ctgcccccga tgagggacga aaggagacac tggccggaat acgagtaaca
    14221 gagagcaccg tgcacgaaga cttcgatctc gggccgcttt tcccggggga gggcaaggat
    14281 cccgtccacc tcgtcgagcg tcagttcgcg cgggaggatg acgcgggaat accctgccgc
    14341 cttcgcccat gccgctcctt ccggtgtagc gattgtggcc tgcgtggacg catggagagc
    14401 aaggccgggg acagtcttcc tggccaggga aagcaggccg gtatcctgga tgattacccc
    14461 atcgacaccc atccggtaaa ggtcaaaaag gaacgagagt gccccggaga gctctccctc
    14521 cctgatcagg gtgttgacgg tgacgtagac gcggactccg gcgaggtggg atacctgcac
    14581 agcctcctcc atctccccgg gtgaaaaatt ggcggcatac tgcctggccc cgaaccgctt
    14641 tcccccaagg taaaccgcgt ccgcacctgc ggcaatggca gcctggaggg cttccccgga
    14701 cccggccggt gccaggagtt cggggggcct ctttgtcttt cccgcgctcc ctgccccgct
    14761 catggaaaag aggtctgcag gagtcaggtt aaagactcct gcccttcaac ggatcccatc
    14821 atgcgattcg tggcctccgt tccggatatc tccttcatcc cggcagcact cgcgtccggg
    14881 gcagacgtca tcgaggtccg cctggacctg accgggtccg tttcaccgga ggaggcaaat
    14941 gccaccttcc gggatctcac ggtcccgctg atctttactg tccggagcgc cgcagagggg
    15001 ggcatgtttg caggagggcc ggaagaatgg tgggatatgg tccggccgtg cctcccgtat
    15061 gccactttca tcgacgtgga gcgatcgttc cggtcctttg caccggtcct gcggagagag
    15121 aaaaagacaa tcattgcatc cttccacacg ccgtcaatgc cggacccggg atcccttgag
    15181 gcattgaggc gggatcttgc cggatacggg gatattccca agatcgtggt aggaccgcga
    15241 tcggaagagg atgtcctgtc cctcctctcc ttcacccttc atgcagaaaa accaattatc
    15301 acgagtgtca tggggtcccg tttctcgttc atacggctga tgcttccctt cttcgggtca
    15361 tcctttatct actgccacgc aggtagcccg gccgcggagg gccagattca cctctcccgt
    15421 gcacgcgaga tcatggggtt gttccgctga ttcatcactg catcgctttc acaagaaagc
    15481 accggaaaag tcattggggg gactttgaga ggaagtccgg ggacttcttt tcatcgcctt
    15541 agagattatc catgcaatgg taaccaaaaa ggagggttcc ttacatctac cggagtgtgt
    15601 caggaaggca ggcaggatct gccagttagc aaattccatg ggatgataat cccgggaaaa
    15661 aaggtctctg gtcccggcat ttgccggatc ggtatcacag ggcacggaca agggggatgg
    15721 cacgaacggt atactcttta aggcactccc cgtcaagctc gagcgtgaca atcctttcct
    15781 caccgggact gatcgtgcca aggtagagtt cctttgtgtc acgcacggct cccgtatctg
    15841 cattcacgag ttctacatgg aggaaaacat ttctctcttc ggtcgttccc gggttgtaca
    15901 cctggaaggt ggtctcccag gtacaaccgc gggatatgcc ccagtccgcg ttctgcctga
    15961 cgaggatcgc cctcatggcc gtcccgttcc ctgcgccggc atcgcccctt tctccgtccg
    16021 cctgggtaag cacggagacg catcctgcgc acgaaagaaa aacaagagct gcaaggcaca
    16081 tgatcagggc cgcacgcaat gcatggtttt cttcggattt cctgcgaggt tttatcatat
    16141 ctttcacccg ttcgaagtgg atccggcgat aaactcctgc cggtatcact gcttacagtc
    16201 ttgccggcaa gggttatagg gtttccatac tgccggggac ccacgatcgc agcatctgcc
    16261 ggccaaggca ggcgtccgca aggacaaggg ccagcatcgc ttccgcgaca ggaccgatcc
    16321 tcgggacgat gcaggcgtcg tgccgcccgg tcaccgagat cgtcgtctcc cttcccgctg
    16381 tatcaatcgt cctctgctcc cgggagatcg acggggtcgg tttcaccgcg atgcgcacga
    16441 cgatctctgc gcccgtgctg attccaccga ggatcccgcc agcatggttg gaaagaaaac
    16501 cgctcccgtc catctggtca ttgtgttcgc ttccccgcat ccgtgcagca gcaaacccgt
    16561 cacctatctc cacgcccttg accgcgccga tgctcatcat ggccatggca atgagggcgt
    16621 cgagctttcc aaagacaggg tcaccaagcc cgggaggaca ccctgttgcg gttatctcga
    16681 tgataccccc gaccgagtct cccgagcggg ccgcatcggc aatctccctc tccatctcct
    16741 ccggaagggt cgccccgtga acctcgagaa ccctgctcct gatcgatatc cccctcccgg
    16801 agagaatttt ttctgccacc gctcccgctg cgaccctcgc cacggtctcg cgtcccgaac
    16861 tccgcccgcc accgcggaaa tcccggattc cgtacttcac ctggtacgtg taatccgcgt
    16921 ggcccggccg gaaaacgtct gcgagagcct cgtaatcgga tgaacgggca tcggtgttcc
    16981 tgacgaggag acagaggggg gttcccgtcg tcctgcccat gaaaactccc gacaggatcc
    17041 ggacgcggtc ctcctccttc ctccgggtcg agaagggatg gatgccgggt cgcctcctct
    17101 caagggccct gttgatttcc tcttccgaga tctccacgcc gggagggcac ccgtcgatga
    17161 ccgctcccag tgccgggcca tggctctccc cgaatgtcgt cacgcggaag ttcttcccga
    17221 acgtgttcac cccatcatct cccggatcat gtggagcggg gcatcgatcc ccgtgaaatg
    17281 gcggaactgt gcctgtgcct gccggataaa catctccctc ccctgaatga cgcggcaccc
    17341 cgcgcttctc gccatccgca ggaggggggt ctccggcggt gtgtagacaa gatcaaaaac
    17401 ggtcatgccc ggaaaaagct gctcccttgt aagcggactc ccccgatccg gctccatccc
    17461 gaccggtgtt gcattcacga ccacagcagg cctgatgcgg tcaaaatccc ggggtactcc
    17521 cgatgaacac ccgaaccgcg cagccagagc ctctgctttc tccacggtcc tgttgaggac
    17581 cgttacctcc atgccgagcg aaagaagggc atatgctgcc gccgctgcag caccccctgc
    17641 cccgagaacg actgcggttt ttcccttctc ctccaaaaga gcgtcccgga tacccatcca
    17701 gtccgtgttg taggcataac ttctcccgcc gcagaagaga actgtgttag ctgccccgat
    17761 cgcggagcag tgttcatccg ggtggtcaac cgcgtcaagc acctcctgct tgaatgggat
    17821 cgtgaccgag agtccccgga cgtcgaggtc cgcggcaagg ttcaggatcc gcgagaggga
    17881 agggtcatgg aacctgatgt aatgggcgtt gatcccaaag taggagaaga gctgggcata
    17941 gagctgcggg ctccggctgt ggagacttgg gtatcccgcg accccgtaaa aacgcaggac
    18001 ggggttgtcc cggatggccc cgatcttttc caggagttcc cgtccctcct gttcgggtat
    18061 gcccgattgc gcaatggccc gggcggcttt ctccatcccc tccacgggca cagtgccctc
    18121 ttccaggagg cgcttgatat gtattgcgac ttcgtttgca ctcctcgcgc tcgtgtcaac
    18181 gcacatatcg gcagcactca ggtaggcatc gcgccgcaca gaaaggaggt gctggatctc
    18241 ggcacggagg cccatcgttg tcaggggcgg ccttgcggtg tcccggatgc gtttctcgat
    18301 ggttgctgca tctgcctgga ggagaacaac ggttcttccc ctgcgcaggt gttccacatt
    18361 ttcgggcgag aggactgcac ccccgccggt tgcaaaaaca ccggggccgg aaggaagtgt
    18421 ggctatgacc tccctttcca gcttccggaa cccctcctcg ccaactgctc caaatatctc
    18481 gtggacatgc gcgcctgcct tctcctcgat gagtgcatcc gtatcgtaaa aaggcacgcc
    18541 gaggagtcgg gccagcagat gaccggctgc tgtctttccc gttccacgga aaccgattaa
    18601 aacgactttc atacaagccc ctgcttggag agctgttccc agaatcccgg gaacgattta
    18661 ctgacacatt ccgcgtttct aatctttaga tttcctgtcg caagcccgag tgtggcaaaa
    18721 ctcatggcgg tcctgtgatc ggatcccggg tcaatctctc ccccgtgcag gggacggggg
    18781 atgatggtaa tcgaatcgtt ttccactctt acccctgccc cgagcgtgga aaggaggcgg
    18841 gccgtttcgg cagggcgatc actctccttg taccggaggt gcccgacacc aaggatccgg
    18901 gttggccccc ttgctttcga tgcaaccatg cagagcgtct ggacggtgtc cggaaaagag
    18961 gtcatgtcca ccgtgatccc gtcaatatcc ccgtcagagg atacctccac ccaatccttc
    19021 cctgacttca cgtggcaccc catccgttcg aggcagtcga ggaacgcgcg gtcaccctgg
    19081 cacgagcggg ggttgaggtt tttcacgacc accctgccgc cgcagagggg ggccagtgca
    19141 aaaaagtacg atgccgacga atagtccccc tcgacacggt accgtgatgg cctgtatcca
    19201 tgacctgcag gcacatggaa acggcgatac ccctcgcgtt ccaccatcgc agagaatgcc
    19261 tccatgacgc tgatagtcac atcgatgtag gactgcgatg caacgtttcc cccgatcgtg
    19321 accgtgacgt cttttcgggc gaggggagcg acgaggagaa tggacgagac aaactggctg
    19381 ctgatccccg catcgatggt gatctctcca ccatcaagcg acccggatac cctcacggga
    19441 gggtacccct ccctcccgag gaacccgact tccccgccaa gtgcccggat tgccgcggca
    19501 agcgggccaa cgggcctctc cttcatccgc cgggaccctg tcagcgtcac gggacgcctg
    19561 cagaggagcg caaccgaaca gaggaggcgc atgctcgttc cggattcccc cgtatcgatg
    19621 acgagaccgt ccgggcagga aagacttccc cccctgcccg atacgaggag accgtcctcc
    19681 cattctctca tcggtatgcc catcgattcg agtgcatttc tggtcacccc cgtgtcgtcc
    19741 gagacgaggg gatccgcgac gtgcgattca ccgggtgcaa gtgctgctgc aatcagggca
    19801 cggtgcgtgt aacttttcga cgggggtgca acgaaggtac agtccagtgg ccccgccttc
    19861 cggagcgtta ggtccattcc gggacctcca gcacaggata ccggccaagg tccttgacgc
    19921 aggtcatctc cttcaattcc tccagtgccg ccagcgaccc ttcacccgaa aactggtaat
    19981 cgatgaagaa gacgtaactc ccgatgcccc tcttcgacgg gcgggactcg atccgcgtca
    20041 ggttgatccc ctttcctgaa aaaacgccga ggatgtcgtg gaggagaccc gccctgtcct
    20101 cgcgcgggtc cacgatgatg ctgcccttga ccggtcggga ccctccatag ggcctggacg
    20161 atatggtgac gaaccgggtc acgttctggt cgctgttctc gacgcaggcc ttctgtacag
    20221 gcaggtcata gaggcgggct gtcatctttg gaacgattgc agcccccctg ccggaacgga
    20281 cgagttcacg tgcgctctgg gcattgctgg gcgtgtgaac aacgggaatc cccagttcct
    20341 cgatgatgtc gctgcactgc tcgtgtgtct ggggatggac gtagataacg cgggcttccg
    20401 cgagaggtcc cagggatacg aggtagtggt gtaccgggac acatgtctcg cccgttatcc
    20461 agaccttaaa cgtgagcaat ccgtccatgg atgctcccac accaccggcc tcgctgttct
    20521 cgagcgggac aagcccatca ccctcaccct tttcgacagc ctcgaagatg cgccggatgg
    20581 tggggacgag ggtgacagct tccccgaata tgcgccagcc cagttcgtgg ctgaaggtcc
    20641 cctcgggacc cagtgcaaag accttcatct cctcaccatg gctgatatca gcatgtcgga
    20701 ttccccggcg gccctggcgc agtaatcccc gaaatggcgc gaattttcaa ggaaaaaacg
    20761 cctgaattca tctgcgtccc cctttgtgac gatcccgtgg agatctgcaa acgattcatt
    20821 gcaagccgac aggactgccg ggacttccgg gttcagcatg aggatatcgg catagaggtc
    20881 cgggtcctgc gagagtaacc tgccaacgag gcacatctcg atctggtaga tcgggctcat
    20941 gaacgccatc gtgtcttccg gcgacatacc cagcctgcgc atcgtcccgg ccattccgag
    21001 ggtgacgtaa tgcgtcagac cctgcacgac tgccatcatc ctgtcatgct cttccggagt
    21061 cgtgatcgtg acgcgggctc cctgcgatcg gaagatctca aggaggtttc cgagggtttc
    21121 ttcatcgcac cgggccgggg ttgcaatgat tgtctgccgg tggaggcttt ctgccgaagg
    21181 cccgaacatg gggtggagac cgaccaccct ggccctggac tcgagcattg cgcggaccgg
    21241 ggcggccttc agggaagtca ggtcgcagaa cacctgctcc tcggagagga ggggggcaac
    21301 ctgccggatg accctgactg tctcccggat gggaacggat accatgacga tatcgcactg
    21361 gttcgcaatg tccacgtccc gcgtctttgt gctcctcccg gacaccatga catcgtggcc
    21421 ggcccgggaa aagacattcc caaagaacgt ccccatcttt ccggtcccgc cgatgattcc
    21481 cactttcacc agggatcact tctccacgat gctttcccgg acagccattc caaagtgcct
    21541 tccggcctcc ttcacgcatc ccatcacggt atcgcctgcc gacagaccta ccacggagac
    21601 cgccgaacca tccttcgcaa cgaggcgtat cgtctctgcg ttctggagga tcaggctgca
    21661 gggaacgccg tcagcctccg cctcgacgag caggagtggt ctcttctcga tcttgacgcg
    21721 cccgactgtc acctcgcggg cgacaccgtc ccgatcgacc acaagcaccc tgtctcctgc
    21781 cgagagatcc gagagatacg atgtttttcc ccccggcgag aggaggtacg catggaccgc
    21841 ccctgcattg acccggaacg gccttggggc cacgtagggg ttctcgaggg tttcggcatg
    21901 gacgaggagg aaggcggatg atgtgttccc gacaaggagg ccttcgccct cggagaggag
    21961 ggaacacgta tccacgcaga cgcggtcgcc catgcctgca ggtcggactg cggtaatggt
    22021 gaacgggaca agggaaacct cctcctgccc gcgatgcatc agtgttcccg tctccttcac
    22081 ggcggccgga tcatccgtat cgaggagcac ccccgcaaca cccttttcca ggacctggag
    22141 ggcgaggaga gcctcctgtg gcgaagtgac cctggcgatg atcctgtccg accgggcgac
    22201 gaggttctcg agggggatca ccttccagtc atcggcatcg atcacgacgt aaccctcccg
    22261 tgccttctcc acggccagct cttcgctctc cctgcccgtg atcgctattt caaagacatc
    22321 ccgtcccggc acgagatccc cgtccggggc aacgactctc accctgccga gcgctttgac
    22381 gcctgccgcg gaatcggcaa cgattgtccc ggcccccgac tcgagcgcgg ccgtggctat
    22441 gttctttctc cagggcctgg catcgaccca gaattccttc attcaatctc ccttgagagc
    22501 ttttttggga tccatctcct cgtgcacgac tttgcagagt gcctcgacga aggcacgggg
    22561 attttctctc tggaaggcgt tccggcccac gcagacgcct gcacccccgg cccggacgga
    22621 atccctgatg atctccagcg tctcgaggtc cccggccttc tctcccccgg cgatgaacac
    22681 cggtactgaa caggccgaaa cgatatcagc gaacgttttc gggtcccccg tgtagtttgt
    22741 cttgatgagg tctgcaccaa gctcctctgc caccctcacg cagtgaccga cactctcggg
    22801 ggacgtgggg ttaatcccct ttcccctcgg gtagatcatc acgaggagag gcattcccca
    22861 gcggttgcag tccttcacga tcatcccggc ggactcgagc atcctcgatt cgttcggggc
    22921 cccgaggttg atgtgtatgg acacggcgtc tgccccgagt gcgattgcct cctcgacggt
    22981 acagacaagc accttgtcat tcgggtcagg gttcagcgag gtgcttcccg agaggtgaac
    23041 gatgaggccg atgtccctcc ccttcctccg gtgacccctc ttgacgatcc ccttgtggag
    23101 gacgattgcg ttcgcaccac cctcgctcac ctcggagatc gtgcgtgtca tgtccttcaa
    23161 tccctctatc tggcccagcg tgaacccgtg gtccatgggc acgatgacgg accggcccgt
    23221 gttccggtcc atgatccttt cgatccttat ctcctttcca atcatgatct cttctcctgg
    23281 agtactttgt atgcctcttc ggcagaccgt ccgtggtgca cgatgagcgc ggcagcagcg
    23341 atgaacctgt cgggtgtcgg atgctggaaa gcgtttctcc cgatggaaat gcctgctgca
    23401 cctccttcca tggccccctc gatcatctcg agcgtggcaa ggtcactcgt tttgcttccc
    23461 ccggcaacga cgacggggac agggcagccc ctcgtgactt ccctgaaact gtcagggtcc
    23521 ccggtgtaaa cggtcttgac aatgtcggcc ccgagctcgg ctgcaacccg tgcagcaagg
    23581 ctcacgtggc tgacctgatg ttcgttctcg atcttccggc ccctcgggta catcatcgcg
    23641 aggagcggca ttccccattc catgcactcg actgcagtgc ggccgaggtc ggcaagcatg
    23701 cgggcctcgg agtcagcccc gatattgata tggatcgaga cggcgtccgc acccatcctg
    23761 agtgcgttcg tcacggtgtt gacgaggacc ttttcgttcg ggtcggggcc aatcgacgtg
    23821 ctcgccgaca ggtggagaat gaggccgatg tccctgccac tcctccggtg cccgtgcagg
    23881 gacaacccga cgtgtccgag gactgcgttt gctcccccct ctgcgacgag gtcaactgcc
    23941 cgcccgaggt ctatcaggcc ctctatcggc ccgctggtga ccccgtgatc catgggaacg
    24001 atgatcgtct tgccggtgtt ccggtccatg atccgttcca gacgaatttc ttttcctctc
    24061 atcatgatct cctgcccatg cagcacatct tttgtgaaaa aacggccgat gggctagtta
    24121 aaaggccaat aataaccaaa aaacgtgcaa ccccgcatca gggccgtggc tcccgaaaag
    24181 gggtgcgcga gaacagatct tttgatactg atgcaagagg cgtcgctagc agagataaaa
    24241 acactcaccg gcgaaaaaac actcaccttg cattggagaa aaaagttgtc cgtttctgta
    24301 tataaaactg atgagcccgg ggttcacttt ttgaccttct tgagagagat aacatcgccg
    24361 agggtcggga cgaccttccc cgcctgcctg gcgctctcct ctgcggatgg agagtctatg
    24421 aggcgtatgt tcagtgcctt ttcaagcttc ttcctgacgt cgtcttccgg gatgaggtct
    24481 cctttctcga tcttcttgat caggagctcc ttctccttga gatgcattgc gagatccttc
    24541 tgggaccagc ccctctccat ccttgcagtg cgaatcctct ctccgtagtc ctcgacgatc
    24601 tctccctcga tgaagtcaaa gacatccctc ttcctttttt caggctgtac caccggcgcg
    24661 cgaagggcag taccggtccg ctggactggt ttttgaatct tgggaacctc tgtaccatac
    24721 cgggcacact gggcacagac ctcgagcacg gccccttcca ccctgaccgt tttcgattgc
    24781 ccctggatct ttgcgccgca catttcgcac tgcatactcg tcgcaaacat ctttatagac
    24841 atttttccct atatacttaa tcgaggcaga aaaatggtgg aaagtgcccg ccaatcccag
    24901 gaaccccaga accccgagga gctctaccgc tatctcctcg acagggtcac tcacatggag
    24961 acccgcaacc tggaactgcg ggaacagatc cgccagattg agtcggacaa gcgctacatc
    25021 gagacccaga agatacggta cgaacgcgag gtcaggaaac tcaagagcga gatcgaacag
    25081 ttgcggagtc ccccgcttat catcgggaca atcacggacg tgctcgacaa cgggagggtg
    25141 gttgtcagga gcagcgcagg cccgaggttc atggtcagga gctcgatgtg catcgacccc
    25201 gagaagctca agccgggcgt ccggtgcacg cttaaccagc agtcccttgc cgttatcgat
    25261 atccttccgg agagctacga cgcccaggtc tacggcatgg aggtcgtgga gagtcctgat
    25321 gagacgtatg cagatatcgg cggtctcgac gcgcagataa acgagatacg ggaggcagtg
    25381 gagctccccc tcaggagacc cgagctcttc gagcgcgtcg gtatagagcc gcccaagggt
    25441 gttctcctcc acgggccgcc ggggacgggc aagactctgc ttgcccgtgc cgtcgcccac
    25501 gagaccaatg cacatttcct gcgcgtcgta ggttcggaac tcgtccagaa atacatcggc
    25561 gagggcgcac ggctggtcag ggaactcttt gacctggcaa agaagaaggc accgaccatc
    25621 atcttcatcg acgagatcga tgccgtcggg gcctcccgca ccgagtcgac gacctctggc
    25681 gaccgcgagg tccagcgcac cctgatgcag ctccttgccg ggatggacgg gttcgaacgg
    25741 cggggggacg tcaagatcat cggtgcaacg aacaggatag atatcctcga ccgggccctc
    25801 ctccgcccgg gcaggttcga ccggattatc gagatcccgc ttcccgatat cctgggcagg
    25861 gtagccatcc tgaaggtcca cacgcgcaag atgaacctcg atgagaacgt ggatctcgag
    25921 gagatagcaa ggctgacaga aggcaagaac ggggccgacc tgaaagcgat ctgcatggag
    25981 gcaggcatgt tcgccatcag gcgggagagg gaggcagtct cgaaagagga tttcctggac
    26041 gcgatcgaga agattggcca ggatttcgag cgccatgtga tcaggacagg ctatggtgcc
    26101 atgtttgcct gaaaagtatc cctttttcca tctttgaaaa ctcatttttg cgacttctca
    26161 tggggaggag tggcaatcgt cgctttagaa acccatatga accgtctcac cccagccgtc
    26221 ccctaccaat accttaatat atttttctct actccatgaa gggtaggtga ttctatgagc
    26281 atgttaaaag aattcatgga cttcctgtat gaatacaagg tcatcgggct cgcaatagcc
    26341 tttatcatgg gccttgctgc caaccagctc gtcaagtccc tggtcgacaa catcatcatg
    26401 ccggtcatca cgtttttcat cccgggcggg gactggcaga ctgcgaaact tgcaatcggg
    26461 ccgatcatca tcagctgggg acagttcctc tccgacctga tctatttcat cattgtcgca
    26521 ttcgtcatct tcctgattgc aaaaaaggtc cttcgcgagg acaaggtcac gaagaagtga
    26581 cgggaaaatc ctccctgtca ctcccccttt tcgcgaggta ctggtccctc gtgcaccaga
    26641 cttcgatcct catctctcct tcgcccgagt tttcaggtgc ctttttccca ctgtctgcgc
    26701 gggcatgcag gggttcatcg ctcaccagtc tcccttcccg gaacgagtaa atgcgcctgt
    26761 atttccacct tttctggagg accggttccc tgccgtaata gatcatccgg gcgatgtcgg
    26821 cggtgcagaa agtgccggga gcgatctcga agatcacgtc gtgcatgtac cggcggacgt
    26881 accatcgcag gtccgatacg agggagaggg cgctcccgag tgatgccggg gtgacctcga
    26941 cgccggcagg tgtccttgcc ggctggtaga agcgcagtgc ctccctgctc gtctctgacg
    27001 agaggagagc ggagtagagg tcaactcctt ccctggggac aaagaccacc cgcatacgta
    27061 acctgccaga tatgtatcac gctgccgtga ataggttatg ctcctccaat ggctccggag
    27121 cagctgccgg gttgactgga aaaaagatgg agaaaaggat cagatataca tgcggaggtc
    27181 cggcgactgt tcgtttcgaa ctttcctgac agactgcagg aaatcttcct gggagactgc
    27241 agcagcctct ctccgcacgg cattcatccc ggcttcgcgg catatcgcct ggagttctgc
    27301 ccccgtcgct cccttcgtca tgcccacgat ggcagaaagg tccacatcct ttccaagggc
    27361 catgcgctgg gtatggatct ttaagatctc cagcctcccc tcgtcgtccg gcagcgggat
    27421 ggcaatgacg cggtcgaacc ttcccgggcg gaggagggcg ggatcgagca tatcgaccct
    27481 gttcgtggct gccatgatgc gcacgtcacc cctcgtgtca aaaccatcca tctcggcaag
    27541 gagctgcatc agggttctct ggacctcggc actccctgac gtcccgtcgt ttgtccgggt
    27601 gctccccaca gcatcgatct cgtcgatgaa gacaatggat ggagactttt cccgtgcgag
    27661 agcgaagagc tcgcggacga gctgggcgcc ctccccgatg tacttgtgga ccagctcgct
    27721 ccccgacatg cggatgaacg ttgcctttgc ctggtgtgcc acggcttttg ctatcagtgt
    27781 ctttccagtc ccgggaggcc cgtagaggag gatccccttc gggggttcga cacccacccg
    27841 ttcgtatatc tctggtttcg tgaggggata ctcaacggcc tcccgcactt cctcgatctc
    27901 ctttgaaaga ccaccaatct ggctgaacgt tactttcggt gactcttcga gttccatcac
    27961 gcggacccgg gaatcaaata tcgacccgac gatcttcacg atggagagtg cgttattgac
    28021 ggcaaccttt gtccccggct tgagctggcg gaagagttca tcgttgacgt gggtgaggta
    28081 ttcctggttg ttcccctgct ggcggaggta gacttctccc tttcccagga ggtcgacgac
    28141 gacggcaacg aagagcggca tgcgcttgag ctggttgttc tcgcgtttga gttgcgcatt
    28201 ctcccggagg agctcgtcgt ttctcacctt caggtcaagg acctgggatt cgagatcctg
    28261 gatcttcagc tgtattttta tctcggtatc ggttccggcg ttcttgatga cgctttcttc
    28321 catgctacac ttatatctga acttccctac atttatgtgg tgtgattgtg atcatccggg
    28381 gacgcgggat atcggggggt tgcgggacgg ggcaggccct cgttagtcct gctgccatct
    28441 cttttctgtc tggcgtcaac cccgagaccg ggacgatcgt cgagaaggga catccgctcg
    28501 agggacagtc catcgccggg agagttctcg tgtttcccca cgggaaaggc tcgacggtcg
    28561 ggtcctacgt catttatgcc ctttcccgga atgggaaggc gccggcagcg atggtcaatg
    28621 aagaggccga acccatcatc gccgtcgggg ctatcatcgg gcgggttccg ctcgtcgaca
    28681 ggctggaggg tggtctctcc cggctccggg acggagacct gctcagggtc aacggggaca
    28741 tgggcacggt tgaaatactg gagaacggcg aagatccccg gaggagagag aaataagaag
    28801 ggatagtctc aagagtctcc cgttcccatt ctcctccatg agacccggaa tgatcatact
    28861 gctcatcctt gccgtttctg ccatcgcatt cgcagggtgc acggaaaccc cgtctatgtc
    28921 atcccagaat ggtggcccgg tgggcattgg cggaagttca tttgccaccg gaccaacagt
    28981 caccctgccg cccgagcaga atgtcgagat acaggtcaac gagaaagacc ccatctacgc
    29041 aaccataacg gttgtttttg cgggaggaaa gggccagatc gcagtgaggg acattctggt
    29101 ccgcgtgacc acctccgatg gaaaggtgac cgaacagcac ctcccgccac aaaagggatc
    29161 tgaagtggta ttcaagggaa caaagggaga cgaccggctg gaggtcaccg tcaccctcac
    29221 cacgggcgca acctataaga tcatcgaccg gatcatcccg taccggacga ggggctaaaa
    29281 gagagaaagg tgtgaccccg gggtgaccgg acacgggaac ccccatcccg cctttcattg
    29341 cccacccatc ctttttcccc ggaaatggac gtctgctgga ggtacatacc tgcggcccgg
    29401 aactcctacg cagcactcta tgccgcatgc gaaaaggaag ggttcgtcct gcgccccgtg
    29461 gatacgccgc agggggatgt gacctgttac agtctgaatt ccctgaacgc tcaccaatat
    29521 atccccgaaa tgaaacgtgc cccctgcatt acaatcgcgg ggggacccca tgcaacggcg
    29581 tgctacgcgg agatcgcatc cattgccgat tacgtggtcg tgggagaggg ggaatacacg
    29641 ctccccgcgc tcctcgcatc gatagaaaac ggctctcccc tgccacgcgg tgttgcaaca
    29701 cgggaaagtt attcctgcgc ggatacatgt gtccgtctcg atgcatttcc cgctttttcc
    29761 cggatgaagg gttacatcga gatctcgcgg ggctgtcccc atgcctgcac ctattgccag
    29821 acaccaagga tattcgggcc tgccatgcgt cacaggagca tcgatgcgat cgtcggggca
    29881 gcccggaaat tccgcgatgc ccggttcgtg acacccaatg cactggcata tggctcggac
    29941 gggatccacc cccgcctcga taaggtcagg tccctcctgt ccgcgctccg gtatcccggc
    30001 cagaaaatct ggttcgggac gttcccaagc gaagtccggc cggaatggat cacggaagag
    30061 gcgcttgacc ttgttaccac gtactgcagc aacaggcggt tgcacttcgg agcccagtcg
    30121 ggaagcaacc gcgtcctctc aatgctgcag aggggccaca cggtcgaaga tgcagaaagg
    30181 gccatcgatc tcatcgtgga tgcagggttg acacccgttg tcgatttcat tgtcgggctg
    30241 ccctgcgaaa cggaagagga ccaggagatg actgcagcgt tcatccggtg gacggcatcg
    30301 cgcggacagg tccacgtcca caggttcatt cctctccccg gcacccccct tgccggtctc
    30361 cctccgcgcc ccctcatacc cgggctggaa agcctgcttg ggaaccttgc actgaagggg
    30421 aagctgacag gtacatggcg tgaccggacg aaaagttttt tttaaaaacc ccttcgaatg
    30481 aatattcaca tgagagatgt tcttctgctg gccgatctcc acggtgaatt cggaaagatc
    30541 gggtcattcc tggatctcgc accggatgcc atcatcatag ccggcgacat caccaacatg
    30601 ggccctgcgg atgctgtcga atccctcttt gaccggatag acgttcccgc atttgcggtc
    30661 cctggcaact gtgacccgag ggagaccgtg gacgcactgg agcgatccga ctgcgtctgt
    30721 ctccacggct cgtcccttag cctgggcaac atcacccttg tcggaatcgg cgggtcgaac
    30781 ccgacaccat tctccacgcc cttcgagatg acagacaagc agatcgatga catcctctcg
    30841 ccgcttgtcg ccagaatgga gagacgtacc cataacgtcc tgatatcgca tgcacctccc
    30901 ctgggcatcc tcgaccttgc cggaggaaac cacgtgggat ccgcgagtgt ccgcaagcac
    30961 atggcgtcat ttgacctcgt ctgctgcgct cacatccatg aacagagggg cgttgccgag
    31021 gaatcgggca tcagggtcgt caacccgggc atggcagccc tcgggcagtg tgccatgctc
    31081 cacttcgggg acgaacccag gtcaatcagg attgaactga cccaggtata acgaaaagat
    31141 acttattacc cctttttcct gcttttttcc aggagttcga ggtaggagtc ctggatgggt
    31201 tttcctgtta caccaagcga ggctgcaaga tcgatgaggt acgacgctgg tacccccgca
    31261 tgggaatcca gttctatctc gacgaattca ccaagacctt ccacggaatc gagtgttacg
    31321 gtcgcgtccc tgacgtggta atactctctc cgtttcctca cctccgcaac gggcctgaat
    31381 cccagcgcga cgaggatctt ctccatggtt tcgcccgatt cgatcccgca gatgatctct
    31441 tcccttgcct tgagagggtg cccggttttc cgcgaaccct tgtaggtgag ggtgtagtgc
    31501 cctccagcct cccgcaaacg gagggcctcg tcagtctttg cgaagtcccg cgcgggcgag
    31561 ttgaggtaaa ggtcacgttc cgtgacggca cattcaaaga ccgcctgcat ggtgtgcagt
    31621 ctctccctca ctgcaccgag atcatccaca cgtgctttca actcgacctc gagcatggta
    31681 caggtctcac atgataatgg gggttttggg atgaaatgag gttttggaaa tgatcgcagg
    31741 aggagtgtcc cggaaaacga gggttctccc acctgccctg ctcgattaag tatatcttgc
    31801 ccgctttgta aatgtattaa gaatcccaac cccggcgggg tcctttcccc agtatcacga
    31861 agccgggggg cataccgggg ataccaggtg ttaccaatgg caatccagaa gggagatttt
    31921 atcaggctca gctataccgg cagagtggac gggactgttt ttgatacgac cgacgaggaa
    31981 gtcgcaaagg aggcggggat atataacccc gaggcaatct atgggcctgt gacagtgagg
    32041 gtcggcagcc agcacgtcat catcgggctc gacgaggccc tcgagggcag ggaggtcggg
    32101 gaggaaggag aactcgagat cccacccgac aaggcattcg gcccgcatga cccgtcgcgt
    32161 gtcgaagcat acaacaagaa tgcattcagg gaaaaaccca agaagggcat gacattgaag
    32221 gtccctgaaa agggcgaggg gaaggtcgtt gatgtcatcg ggaacagggt attaatcgat
    32281 ttcaaccacc cgcttgccgg aaagacgctc tcctaccggt tccgcgtgga cgaatgcgtc
    32341 acggaacccg tcgagcaggt caggggctta atcaggttgt atgcaggcag ggacatggac
    32401 gtctccctgg attccggagt gctcaccatc cacctgccgc cggggatcac ctacgaccgc
    32461 aggtggctcc tgtggagaag cagggtcatt caggagacct tctcggccat tcccggaatc
    32521 gcgcggatag tcctcgagga gacattcaac aggcccgggg aatcagaacc cgtcgagtaa
    32581 ataccatctt tttttccgtc cgcaatcttt tcacaatgct tctctgcaga gaggtgacag
    32641 tttttcaatg agcctgtcga cctgtgccgg tgccgtgccg atgtaccggg cagggtcgag
    32701 gagagcccga atctcgttga cgggaataat tttagtgacg tcgctgttac ccgaaaggac
    32761 ttcgatgagg ggtacattcc gttcaagtgc ctccatgctt gcctggcgga ggatctcgtg
    32821 agccttctgc cggtccatcc ccctctccgc aagggcaatc atcactgctt ctgccatgtt
    32881 gataccatgg aggagggaga ggtttgcctc aatgcgatcc ggcttgagga cgagcccgtc
    32941 gaggacaccg gtcatcacgc tgagaatgtg gtcggcaagg acgcttgcct ccgggaaaag
    33001 gacgcgctcg caggatgagt tggtcaggtc acgctcatcc cacagggtat tgttctcgag
    33061 cgcgggggaa accgaggagc ggacaacgcg ggcaagcccg cagacctgtt cgctcctgat
    33121 cgggtttctc ttgtggggca tggtgctcga cccgacctgg cgcgacccga acggttcctc
    33181 gacctcgccg atctcgctcc gctgcagggt acggatctcg atcccgattt tatcgagggt
    33241 cgttgcaacg tttgccagga acatgaaata ctcggcatac ctgtccctcg atatcacctg
    33301 gttggacacg tcgacggggg atagcccgag cagttccatc atcgtcgcct gcacttccat
    33361 ccccttcccg ccgatcgccg cctgggtccc gacggcacct gtcagctgcc cgactgcgat
    33421 ccgggccttc agctgcccca gcctctcgat atgtcgggcg atttcgcttg cccagatggc
    33481 aaaacgaagc ccgtaggtcg ttggaactcc aatctggcca tgtgtccttg cggcacagac
    33541 aagtacgcgt gtctcccctg ccctgcgcac gagaacggca agcaggcggc gcagtttcct
    33601 gtcgaagaca cgcgttgcct ccgcgagctg gagaccggtt gcggtatcca gtatgtcgtt
    33661 cgaggtcgcc ccgaaatgga cgtatccgcc cccctccccg cagtgctcgg caatagccct
    33721 gacgatggcc atcatgtcat ggtggatctc ctcttcgatc tccttcgcac gggagagggt
    33781 ggccctgcct gcccctgccg caatggcatc ggctgcccgt gcggggatga gcccgtgcct
    33841 tgcgagtgcc tgcgcaaggg caacctcggc cctgacgatg cacgagaacc ggaagtcctc
    33901 gctccatatc ctccgcatct cttctgtgcc gtaccggtac tcgatgggat ggattgccat
    33961 ggctaaaagt tggttctccc cgataataaa aaggagtcag gggataaaca ctccttccca
    34021 atgaccggtc ttgaggactt cttcccgtac cctggtttcc gcccgcacca gcgcgagatg
    34081 ctcgagttct gctccgcgtg tgcccgggac ggcggcatcg ctctcatcga tgccccgacg
    34141 gggagtggaa aatcgagcat tcttgccgca ctcgtggcag ggggcggggg caggagggta
    34201 ctcgtggcag tccggaccgt gagccagttg aacacgttca tccgcgaggc atcgctcatc
    34261 cgcaggaaaa agcgggatct ccgggttgca tacctggttg gaaagagggg gatgtgcccg
    34321 ctttcgggtg agggcgatgt ctacaggcgg tgcgaggggg tcaaagcatt ctcttccacc
    34381 ctcatgcgac agagggctga aaacggagcc ctcgtcccct cccgcgaccc cttcatcagg
    34441 cagcagatac agaggatgga tccgcaaagg ccgatcctct gtcccttctt cattgcaagc
    34501 agggtcttta tccggtccga atcggggctc cgcatggcac cttccccgga gctccgggct
    34561 gccgcagacc gggtcctccg cgaggatgtc tggccccgcc agctccagga cgtggcacac
    34621 ccggtctgcc cctacgagat gatggtgctt gctgcacaga aggccgacgt aatcctcctc
    34681 aattaccagc acatttttga cgaggaaatt tcgagaaccc tttttgcgaa cctcgatatc
    34741 gacccttccg agaccatcct cctcatcgac gaggcccata actgcggtga tgccgtgtcc
    34801 gcggcacaga gcgtggcaat tgaccaggtg atcctcgacc aggccgggca ggaacttgcg
    34861 ggatttgccc gcaagaaggg gacagcggca gccctccagc aggttctccc gcggatatcg
    34921 gagttcatgg acggcgtgaa gaactctccc gaggcagaag actggtttga cccgggcatc
    34981 tttgacagga tggtggtgag gggatccctc tacagggaca tgggtgcaat cgttgatgac
    35041 ctgatggaac tctccgaaaa gatccacgag aagaacatgc gtgacgggga tttccacgag
    35101 agtgccatcg agaaactgac ccgcttcctc ttttcgctct cgggttcatc ccatgatccc
    35161 tctttcctca cgcttttcca gaaagacgag ggcagggtta cactcgaagt caggtgcatc
    35221 gatcccggca tcaggttgag cgagattgga agctcgcacc acgcctgcat cctcatatca
    35281 gggactctct ctcccgtcga gagctatgcc cgcctctact ttcgtgatat tgccgtcagg
    35341 accctctccc tcccgaacgc gtttccccga aaaaaccgtc tcgtgctctg cgcaaaagat
    35401 atcacgacag cttactcgat gcgccagaac gagtccaatc tcgacctgat agaggattat
    35461 atcagggaat tttccaacct tccggggaac gttgcagttt atttcccttc gtaccagttc
    35521 ctcgaccatt atgcaggccg cctcggcgaa agactgggaa acaaggtcat ctacgtggaa
    35581 ccccgcgacg cgcgcgaagc cgatgagtcc ctccgggagt tcctctccct gccgggttcg
    35641 gggcggtcgg gcatcctcct tgcggtgtgc gggggcaagt ggagcgaggg tctcgattac
    35701 cgcggtgaac tcctccgggc tgccatggtc atcgggctcc ccctggcacc cttcaatcat
    35761 gtccggaaga tgatcatcga gtattacagg cggcggttcg gggaagaggg ggaatttctc
    35821 tgttacacgc tccctgccgt caaccgggcg cagcaggccc tcgggagggt gctccggaca
    35881 ccggaggaca ggggtgtgct cgtctttgga gagaagaggt tcctcgaagg gagagtcaac
    35941 cgcgggctct cgccgtggat cagggaagaa ctccatccct gcctgttttc cgatttcaaa
    36001 aaagttgtca ggtcgtggaa atgagggaag gatcctgtcg cctgggtctc tggcacgtgc
    36061 acgtgtactg ggagggttca acagtctccc gggtgaggtt ctcccggact ccccttcccg
    36121 gtcccgtgcc ggtccagttc aggcggtatt gtgcaggaaa aagggaagat tttgccgggc
    36181 tgaccagcat tgccctctcc catgagtatc cctattctgc catttacagc gaagtcagga
    36241 aaatccccta cggggagacg cggacgtacg gccaggtggg ttcggccctc cacgtgtcac
    36301 cccgcctcgt gggcctcgca atgaagagaa acccgacccc cctcatcatc ccctgccaca
    36361 gggtcgtttc gaggaacggg ataggggggt tttctccgga ccccgagctg aagggagtgc
    36421 tcctctccct ggaacagaaa aataaaaggg ttttatcgcg gtgaggtgaa atgaatccgg
    36481 tgtgcaggac atgataccag cgcaagggga ttgccaagtg ggggcttgcg ttcaccctgt
    36541 cggtgagtcc cgggagggag gtcagtgaga gcctccctgg ttgcatgaca cggagatcag
    36601 ccatcatcct cgtcggtggc gaggcgaagc gggcaaacgg gcaggaaaag tacttcttca
    36661 cgatggacgg gcgcacgttc atcgagaggc ttatcggaag cctggaacag gtcgttgacg
    36721 agatcgtcct tgtcgccaag gaccccgccc agtgccagcg tttctcccac ctcggaggag
    36781 tccggtgcgt gacggatatc aggaggggga ggggaccgat aggtggtatc cacgccgggg
    36841 cacgtgcagc caccggagac ctcgtttttg tttgtgcatg cgatatgccc tgtgtttctc
    36901 ccggtgtcgt ccgggagctc ttctcgctca tcggggatgc agatgctgtc attccccgct
    36961 gggatggcga gatgctggaa cccctgcatg cggtgtaccg gagaacttcg ctcatttcct
    37021 gcctggaaag gcaggatccc ccgtcgctac gggcactcgc cggttctctt cacgtggttt
    37081 tcgtggatgc ccgcagtttc ggggagatag acccgggatt gcgcaccttc accaacatca
    37141 acagccccga ggatctctcg tccctttcac gaggggcatg agagagttgc cacaggtgtt
    37201 acatccgctc ccgggccggc agggacacgc atctggaccg ttgccgagag atcgtttccg
    37261 gagaactcta caaggtaatc ccctgccgat cggatcgtca gtaccctgta cctgtcgacg
    37321 ctgtatgtcc gggcaaaccc gtcctgggct atgatattcc cggatgccct gtcacggact
    37381 ttgacttcga ggtatgcatt cgggctgatg acagtctgcg tgacgtagac gtcatccctc
    37441 gtggtgaacc tgctctcgta ccagatattc ctcgtcacca tctttgggga gatgcatatt
    37501 tcgatgatga gggggggatt ttcgacggtg acggaataag cagtggcatt gttggagaag
    37561 gggatcacgt tccggtagac cgctttataa accgtctgtt cgtaagtggg ttccggcatc
    37621 ttgctgtagg atacgggtgt ttcgggtggt aacggtgtgg ggaaaggtgt tgcctgcgtg
    37681 acgacccggg tatcgatgat attctgcgtc ggtgccgtag tagcctcctg cgtgcctgtc
    37741 cccccgcttc cctgcgtgat tttcccttta ctctctttgg gtggcgtgat acacccgcag
    37801 gccaggactg ccacaacgag gataatgacg aggagacaga cgattcctcc acccttcata
    37861 agaaaaagag attgtattgc cgatatttat gcatttatac tcgaaaagat gaaacggaat
    37921 gtatctcttc ccgcgggatc catccatatt tttataagtt cagtcaggaa atcattctgg
    37981 caggagaaaa aggatctctg cgtcccatgg aaaagaagga aggattctgg aagaaggtcg
    38041 accgatccct gaatgttgcg gacggttatg tcctcaaggc agatatgctt gcccatgaca
    38101 ggcggttcga ggaagcagtc gagtactatg acaaggccct cgagatcgtc ccgggaaacg
    38161 cggatgtatg ggcattcaag gggataaccc tccagggagg gctcgggagg gacgaagagg
    38221 caaggaaatg ctgggaacgg gcaaaatccc tcgaccatac cctggccatg gcagtggaca
    38281 tgacaaagga agagaccggc aggggagtcg aggttgaatc catcccctgg tccgacctaa
    38341 aggacagctg ccgcgacaag ctcaagcgga tgatgttaaa acaggctcag tccgagagaa
    38401 aaggataata cttttttact tctccggact ctctgcaatc tccatttcga cgaggacagg
    38461 ggcaattgtc ccggtatcca cgcacctctt tgcaaggcgt gtcaggcggc ggacatacat
    38521 gatatgtgcc acctggaacc cgacgaggag gccaaagcag agcgtgacga tgctgatgac
    38581 tgtatacgcc gttatgtcaa ccattttctt cctctccctt ttcttcagga ctccctctcc
    38641 atctccgtga tgagtggaac gatggagtcc gcccgctcac actcctttgc aaccgcgaga
    38701 aaccgccttg aatagtatgt attcatcaca aggtgccccg cgaccagccc gatgacaaac
    38761 atcagcactg cgatgatcag gtaaatgacc agttcgtcca tcctctctca cagtttttac
    38821 agagcgggga tatgataaac ctaaccacac agggaaaaaa ggagcgtgtc gtaccctggc
    38881 aggcatgtat tgtattattt gccggaaggt gtctccctgc agaaaatgta tgcagggagc
    38941 cggagccttg cgtggaaaga tgtgccggga tagatctcgc gggtcagttc cagactgcag
    39001 ctgtcaaggc catatcccct ttcccggtca tgcatctcct cgcacgactt gtaaaaggca
    39061 acgagtgcct gccccgggtc atctcccgag agcagcacag gagagatgat cgagaccagt
    39121 ctccggcctt ccccgtccgg gagggggagc ggagttccat cgacatggag agaagcccca
    39181 agaacccggt acgtgccatt ctcctggaac gagaactcga gcgttattcc tgtctggtgg
    39241 agtccctgca tcccgatagt aataaaattg accaggaagt cgtggaaagc ggagaggttc
    39301 tctgcctgtt cactcttcag gcaggcaatc acttcgtccc gcgtcttttc aggaagtgtc
    39361 gggtctttcg agagttttgc gatcagcagg tccctctctt cgaggtgccg aatcatctta
    39421 cggagagtgg caaaggtctt ccagaacgtg acctcgtgga tgcccgggtg aaccgtgact
    39481 cctccggcct gattctccct attttcctcc attttttcct ttcgtctcca cattgccctt
    39541 atttgggttc gagatctgct gcatcagggc cttcctcttc ctgtgttccc ttatctcgtt
    39601 gaaaatgagg atgaaattga atcccaccac gactatgatg agtgtggagc tcatccagaa
    39661 gagcggggtt ataccctgga cgatgaaggt cgttgcaagg aggagagcaa cgaaacagat
    39721 gaggtaaaaa aatatccagg gtctgatatt catgagctcc atgccgttat cagatggtgt
    39781 gttctcctga aatataggtt tggaaggtat caggttgccc tgtcgggcat gagactgcct
    39841 ggcagatcaa ttcgggaact tggatatccg gctcatgtcc tctccaggtg tttttctgga
    39901 acccattccc tcgtgccgga gaattgcctc tcccttcttc aacccgggga cgcacaccgt
    39961 cattgatttg ggaagggcac cgttccgttt ttatggtacc ctgcatcata ctgatcatac
    40021 catgcccact ccctcccgca tccttgcatc tgcccaccag acgctcgagg agaggaggga
    40081 taccgtcaag ctgggcatca tcgcgatttt tgcagtgacg tccctcatct ttacgctcta
    40141 cctcattgtc acccgcgacc aggcctttgc tgcctcgctt taccccctga tcccccatct
    40201 ctacctcatc ccgatcatcc tgctcgcgct ctggtacccc cgccggggcc tccagatcac
    40261 gctgctcctc atcgccgcaa tcctgctcct cacaacgttc ctgttcctcg agggaatcgt
    40321 gttaaacccc ttcatcgccc tcctcaatgc gggtatggac atcgcgatct tcgttgccct
    40381 tgcactgtat gcaaaggaca ggactcttgt cgagtcgttc ctgcgggggt tcttcgaaca
    40441 ttccggcctt ggagagacgt tcgaggaagc aatggaacac ccctctgtcc gggcgaagat
    40501 caagttcgag ggggcattcg aggacgttat ccgtgcactc cataaccctg acgaagaagt
    40561 gcgcgaggag gcggcacggg cactcgggga gctcggcgac ggccgggccg tggaacccct
    40621 catcgggctg ctgtcggatg aaaaccggta cgtgaggagg gaggctgcca agtcgcttgg
    40681 gaagatcggg gacgaacggg cgattgtccc ccttatcaat gccctcaagg acgaggaccg
    40741 gtacgggcgc gagggtgccg cggagggact cggggatatg ggagaaaaag ccttttccca
    40801 cctcgtctct gccatggaag atcccgactg gcacgtccgg acaggggcag cagtcgccct
    40861 caggatcatc ggtgacaaga gggcactccc cgcccttacc cgggccatgc aggacgagaa
    40921 caggttcgtc cgccgcgagg tcatcaagtc cctcggccgg atcggtgacc acagtgtcat
    40981 cgacactctc attgccgcgt tgaaggaccc cgaccggagc gtccggctcc gtgcagtgag
    41041 tgccctttcg aagtgcaacg acccgcgggt cgtcgaaccc ctcatcgagg cgctcaacga
    41101 cgaggactcc ggtgtccgtc tccgggtgat acgggcactg gaggagatcg acgacccgcg
    41161 ggcagtcgag gcgttgaaca atactattta aattttccct tttgttttac agggttaccc
    41221 tccggtaaaa tgcctttttc gtaaaaaagg gaggggctat gaggcaaatg tttataaata
    41281 gagaagataa tctacacttg caggctaacc ggagggatcc gttagtcttg cgaggtgtag
    41341 actatgagaa aagatcaaag aaacgatgac gcgttcaccg ggcttgaagc cgcgattgtg
    41401 ctgatcgcat tcgtggtcgt ggctgcggtg ttctcgtatg tagtgctcgg cgccgggttc
    41461 ttcacgaccc agaagagcca ggaaacggtc tactcggcga cgaaacaggc aagcgcaaac
    41521 cttgcggaat cgggacctgt cgtgctggaa acggatggtt caagtgcggt aaaaaacatt
    41581 tcgttcaacc tcaaaccagc cgcgggagcg tctcccattg acctgacccg gattacgtac
    41641 catctcacca cgaccgctca ggaagcatta tacgtggacc agaaggcaaa tgggacgtat
    41701 aaaatcaaca ggacccagat cattggagat ggtgacgacc ttcttgaaac cgatgagatg
    41761 ttcagggttg tcctcaatgc ccaggatcct ggtgttgaaa taaataagac tgctgtgttc
    41821 tccattgaga tcaaaccgga cgtgggagca tcactcctcc tccagaaaca tgcaccgcca
    41881 gggttaaatg cagacagttt ctacgaggtg tattgaaatg acccggaaaa acattgataa
    41941 cgagagggca ttcaccggtc tcgaagcagc aatcgtcctg atcgcattcg ttgtcgtggc
    42001 tgcagtcttt tcgtacgtgg tgctcggggc agggttcttc acgacccaga aaagccagga
    42061 aactgtctat tcggcaacga aacaggccac ctcgagtttc gaggtcattg gaagcgtcta
    42121 cgggatggca aatcaaacca acgcacccta tctctcgcac gtaaaattca ccatcggtaa
    42181 tactgccggt ggaaccgcgg tagatatgac caaggttgtc gttgagtata ccgatgagaa
    42241 acagaggtgg tatggtgatg agtatggtac acccaaagac ggcatcacag aagattggct
    42301 aaagaccaac accactccaa tgtggggtat tcttgacagg gtcaacgccg atactgatga
    42361 cctgctcgaa cccggggaac agtacatcct gggaattaaa cttcccaata ctacaacacc
    42421 aagcaccact ttcaccctga cccttcagcc ggcaagcggc gcagcttatc cgatcgtgcg
    42481 gagagtcccg gcaggaatcg acatagtgaa catccttggg acctgaaaaa tcccaaaact
    42541 atttcccttt ttctcgttca tcaacggaat ggactgtcac tcttcaccat tgagannnnn
    42601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    42661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnatttc cctttttctc gttcatcaac
    42721 ggaatggact gtcactcttc accattgaga gatgtctctg gcacaatgat ggtatgatgg
    42781 aaactgactt ttcacaccct catcattcac gctggtgtgg agtgcaagag tgatatccat
    42841 tatatagatt taattctata ataatacctg gaacagggta acctttaata atcttcaata
    42901 aggagaattc ctcatggcag tcagtcagtc ccaggtcgac cacatcatcg catctgcctc
    42961 ttctgacgac ccggaggtca agctcctcaa gctccaggac gaggttgagc tgatcaagac
    43021 ctccatcaag cgactgctga tcgatatccg ggaacggatg aacgacctcg agaaccccat
    43081 cgtgtctgca gggggcgggg cctccggaga agacgtttct gcaaaaatgg caagcgttct
    43141 caaggatacg tcaagtgcca tcgagtctgc tgcaggtgcc atcaaatcga cagccgagac
    43201 aaagaagacc gatgaaaagg aggacaaggg tgccgggcag gatacccggg tctcagcgca
    43261 ggaacagcag gtacctcagg cttacccctc cgctcagggt gtcacccagg gagtcccggc
    43321 gacgcagcct tcagtcccgc ccggaaagac agacatggac tttctggctg ctctcaagtc
    43381 ccagcttgca tcgctcccga aagaggagga gggtgcaaag gcggctgctg gtgacaaggt
    43441 caggctgcag aaggtcttcc gcctcttcga atggacatcc cgcaacgtca agcgtttcgg
    43501 gcatgaccgc gtcgacctga tgctcgatgc ctaccacgcg atgggctaca tctctgacaa
    43561 gtcctgcaag ctcgtcaaag acatggcacg cctcatgccg accagcatcg gggagctgca
    43621 cgagatacgg gcagacgagt tcgtatccga gctctacgag ctcaaccata tcctgaaccc
    43681 ctcggactcg acactggacc gcgacatgat cgaggtcctg atggagaaga gggaagggag
    43741 ggatacccag aagtacctcg ctcccgggcg gcatccccgc gaagatgccg gggagcaagg
    43801 atatttaccc tcccgtgaca gaccgtaggg tgagatgtca agcgagacca tcgtcactgc
    43861 cctttttctc atcagtgccg ttatagccgc gggtgtgctc atcaacgcga tttttcctgc
    43921 catttacagg accgcagaca cctttggctc cgtctcgaca caggcagaaa ccaaaatgcg
    43981 gaccgatttc cggatcgtca acacgtttgc caatgacacg gccgtcaagg tctggtgcaa
    44041 aaacgtggga accgcacgta tccatgtcaa cgagatcgat aatggcgata tgtatgcagg
    44101 caaccccggg aactttgacc gctggtcgct cgaggggctg tacaacaagg gtgacctcgt
    44161 taactcctac tgggatcccg gtgagacgct gacgatcaca aagactggca ttggttcgta
    44221 cctttctggg gacgacgatg tctatgtcgc catcgtcctt ccgaacgggg tgaggaggga
    44281 cctgacattt gccaagttct caagctgata aaaaggaggt ctgaatggca gcagcaagtc
    44341 tcgttgcgac tgcatttgga atcatcatca tcatcatcac ggcgtacgtc cttgccggga
    44401 gcacccttgc cacgagcgaa atcgtgacca cagcccagaa ggacatgacc gagatccagc
    44461 tcaaaatgct tgggacatcg cttgagatcg gagagccacc agtcaacctc acgagtccgc
    44521 tgtcaatcac tctcaccaat acagggaacg agccgatccg ggattttaaa aacatggagg
    44581 tctatctctt cttctctgat acaggacccg ttttgtataa atactcgccg ggaggcggtg
    44641 atggctggtg gaatgatagt aggtccctcg gatattttta tcccacccag tgggatccgg
    44701 gggagaccat gacgatgatc atcacctatt ccgagtcttc aacacctatc ggaatccagg
    44761 tcacaacacc caacggtgta tcggcccgca gggtcctttc ttaaaatgca ctgcctcctg
    44821 caataattta aatagaaacg gagaacaaaa tcacaatact tattatggcg gggtcagtca
    44881 gcgaggggct ctccagcctc cttggcggcg aggacaagaa catcctctcg accggaaaca
    44941 gcgagatcga caagaaaata gccgatggta tcccgcttgg ctcgctcacc ctgatcgagg
    45001 gtgaaaacga taccggaaag agcgtgctca cccagcagat catgtgggga gccatgaagc
    45061 aggggttacg ggtcgatctc tactcgaccg agctcaccgc gaagagtttc ctctcccaga
    45121 tggagtccat gagcctcgat gtctccgact actttgcctg ggggtatatc cgcctcttcc
    45181 acctccacat ggtcgggttc aagtggacga aggaagagat ggacggcatc ctccagcgga
    45241 tcgtcaacca catccgccag agcaaggccg aggtcgcggt catcgactcg ctgacgatgt
    45301 tcacggaata cacggaacag tcatccatcc tctcgttcct gacgaactgc aagaacctcg
    45361 tggaccatgg aaagaccatc ctgatcaccc tgcatacgta cgccttcgag gaagacaccc
    45421 tcatccgcat ccggtcgatc tgcgatgccc acctctccat gaagaaggcc ttgatcgggg
    45481 acaagtacgt gatggttctc gaggtggtca aggtcagggg tgcccgcaag acgaccggaa
    45541 atctcgtctc tttcgaggtc caccccggtt acggaatgaa gatcatcccc atatcgatgg
    45601 caaaggtgtg atcggcaatg tcctccctca cagcagccct caccctcccc ttcaagccgg
    45661 cagaaaacac agaggacaac gactgtgcaa acaacatcga aggctgtgca ctgtaccgca
    45721 tgctgccggt gaatgccaag gaatacgtga aaaaggcacc gcacctcctc gaatacctcc
    45781 acatcttccc tgtcgatgag tacgggatcc ccctcttctt ctccgagctg aaacgtgatc
    45841 tcaagtcgat gaccgaccca aacctcatct acccggcgga tgacacggtc tttgtccaca
    45901 tcttttttga cccaaacgac gtccgcaatt actacatccc cgtcgacccg tctttcatgc
    45961 acagtgtcaa ggaactcctc cctgccgtcg agataaaact cgtggacctg ctggacgctc
    46021 tcgaagagga cccggtcacc gacgaggaac gggccgaggt cctgaagcgt ctcatcagcc
    46081 aggtcctcta tgtccgcaag ccgggcgagc aggttgcggc gctaccggga aaaacgaacc
    46141 agaagggttt tggagcaaaa ctcaaggatt tcctcaacaa ggacctgacg gccaggacca
    46201 atccccacaa gacggcaatc cttgccagcg ttccccagac acctgacggc cggatcatcg
    46261 tgtcaccgca ggagtacagg gcaatcgagt acatgatcat ccgcgacaag atcgacgtgg
    46321 ggctcctcaa accgtttatc aacgaccggt acatcgaaga tatcaccgtt gacggcgttg
    46381 gtcccatctt cgtcgagcac aagatattca agggattgaa atcggtcgtc gggtgggaca
    46441 acaccgaaga actcgacaac ttcgttatca agcttgcaga gcggaccaag aggccgatta
    46501 cataccgcaa ccccatcgtg gacgcgacgc tcccggatgg ttcgcgtatc aacatcgtgt
    46561 acagcacgga tatcagccgg aaagggagca actttaccat caggaaggcg atggacgacc
    46621 cgatcagcat cctgaaactg atcgagttca agacgtgcga ctacatggtt gcagcatacc
    46681 tgtggatctg catcgagaac gggatgtccc ttttcatgag cggcgagacc gcgagcggaa
    46741 agacgacgag cctcaatgcg ctcacgacgt tcatcccgcc cgagaacaag atcgtgacca
    46801 tcgaggatac ccccgagctc caggtacccc acaagaactg gacccgggag gtctccaagg
    46861 gcaaggggaa gggcgagggt gagggatcgg atgtcaccat gttcgacctc ctcaaggccg
    46921 cactccgcca gcgcccaaac cagatcctcg tgggtgagat ccgtggtgtc gaaggctcgg
    46981 tcgcgttcgg tgcaatgcag acgggtcacc ccgtcctttc gacgttccac gctgcttccg
    47041 tggaaaagct catccagcgt ctctgcgggg accccatcaa catccccaaa acgtacgttg
    47101 acaacctcaa catcgtcgtt atccagagtg ccgtcaagcg cccgagcggc gaaactgtcc
    47161 gccgcatgct gagcgtcaac gagcttgtcg gtttcaatcc cgagacccag gggttctcct
    47221 ttgtcgagat gttccactgg gaccctgtca ccgacaccca cgagttcacc ggcaagggga
    47281 gcagttacct gctcgagaac aagattgcga cgatgctcgg tatcccggaa cacaagaaag
    47341 ccgcaatata cgatgaggtg gaaaaaaggg cacggatcct cgaacgcctg cacaaggccg
    47401 ggtacacggg cttctacgac ctctaccaca tgatgaccaa gatcaagaag cagggactcc
    47461 tcaagatcga tatcgactct atgtagatgc cgctgacagg gttcggtgaa aaggtccgcc
    47521 aggccaacgc aggaaagctg ccgttccagg acgctttttc atcaatcaaa gagaggtttt
    47581 cgggactctc ggagaacaag aggatgggtc ctgacctcct cttcatggtc acctacatgg
    47641 cctccatcac gaccgcacag gcgacccgcc cggaaatctt tgcatataca gcggccagga
    47701 aggagtatgt ccccaccaag tacatagaaa ggattgaatt tttcgtcaag cgctggaact
    47761 acagctacgt ccaggccctc tccctgatgg ccgacaaggt ccagaacgat atgctgcgga
    47821 gcatgctcca ccggtactcg aattccatcg agtcaggagt ccccgacgag gatttcctga
    47881 caagggaact ttcgaccatc cggagcgtct accggaatgc atacgagcag gggctcgaga
    47941 tgctcaagaa gtggagcgat gcctacatcg cgatgctctt ttctgcaacc cttgtcggaa
    48001 tcatcatgat gatatcggtt gccatctttg cacccgacga catccagcag actctcattt
    48061 cctcctacat gatcgttctg gcagtatccg tcttcggtct cgtgacaatg tacaaatcgg
    48121 ttccccagga tgacaagaca caccacctcg ggaaggggtc aagggaacag aacttaatac
    48181 gcagcctcga gaggaagatc atccccctgg ccttcatggc tggcatcatc ctcgcggtcc
    48241 ttaccacgaa tgtcgggctc tcgatgctca tgattggact cctgctgctt cccctcgggt
    48301 tcatcgggta cctggacgac aaaaacatta tcgtccgtga ctcggaattc acgacattca
    48361 tccggtccct cggtgccgtc atgggaggga agggaatcac cataggcagc gccctctcgg
    48421 aaatagaccg gaaatcactc gaagccctcg agcctttcat caacggtgtc tactcgaagc
    48481 tgaacctcgg tctcgacgag aaacttgtgt ggcagcgttt catctacgag tgcgggagca
    48541 acctgatata caagtacctc aacatcttcc gcgactccgt cgaactgggt ggaaaaccgg
    48601 atatcatcgg ccagatcgtg ggttcatcga tgctggaaca ggtactcctg cgcgaaaaaa
    48661 ggaacaacgt ttccatgggt ttcgtcatcc tcctcatccc catgcacgcg atgatggtcg
    48721 gaatattcct cttcctctac cacatcatgg ttaccatgtc aaaagcaatc ggcagtgtca
    48781 tttccacgat gggatccacg gcagggtcag ccctttcaca accgggaacg atttccggaa
    48841 gcctggcggg ggggattaac ctctttgtca atttcccgga gtacgagatg agtgtctata
    48901 ctgttatcat gatctccatt ctcaccgtgt cgaatatctt tgcagggagg atcgtgatgg
    48961 gcggggatcg ctacatgtat tacttcttcg gaagccttct cctcggggtg acgggcatca
    49021 tttatatcgt cgcgccggta atagttggta tgttcttcaa cattccaaca ttccagggga
    49081 tttgaaaaat gcaggagtca acggtcaggg taattctcct cgtcgtcatc atggcattcg
    49141 gaaccgtgat gctccttttc cctgtcccgt tattctacct cctgcttggc gccatcgcac
    49201 tcgctctcct cgtcctcttc ctcacaggga ccatcaggat gccttccctg aaacgaaaga
    49261 agaagtcaga aactgccggt cccagacccg aaaaggagca gaaagtcaga aaggtaaagg
    49321 aaaaaaagga gaaaaaacca aaaacccgcg aaggcgggcg aaaatttccc gaaattatct
    49381 cttccctgaa aaaggcattt gcagttcttg gcagagacct gaaaaaagca cgcctttcgc
    49441 gggatgaatc gccagagcgt gcaaaaaaaa tcgacacgct gctcgaccag acagtcaggg
    49501 gtgaagcagt cgcatcactg gatgacatcg tccctgactc ggtccccgcg gagaaaaaga
    49561 aagcagagga tcccttctca gccctcgtgg gcgaagacct gaaccccgat ctcctgggcg
    49621 agatcgagcc tcccggcgac ttttccatcc ccggggatga agacctgggc atcgaaattc
    49681 ccacgcagga tttcattgcc ccggatacag gcgtccagca gatggacctt tcactcacat
    49741 cggacgaggc tcccatcgcc attgacgaga cgaacgatgc tgacgaggtg aaagagatcc
    49801 tcgaagccca caaggacgag atagggatgc cggcaactac catggagatc cccttgccgg
    49861 aggaggacct gggtggcctc gataacctcg atctcgatgg aatcgagatc gagggggagg
    49921 gcacgtctcc acaacctgct gccccgctct ctgcgggagg gggcactggc ccggccgcaa
    49981 agggtccgat ggcaacgccg gcaccggcgc ctccagccca ggaacaaaaa attcctgcct
    50041 cgctatccca gcccgagacg gagatgctct cctttggaac cgggaaacgc gaggatgatg
    50101 acctgatggc ctccctcaag tcagaggcaa aggtcaagaa aaagagcgaa tatgcaagcc
    50161 ttatcaggga tctcaaagat atcaaggtta acgcatccga tctccagaaa gaacttgaag
    50221 acctcttgaa accaaggaaa ccgggaaccc gttgatcccg gaaggattac gcaccatggc
    50281 gctggtaccg gtcaagatcg agaaggacgg gaaatggctg gtcggcaaaa tagacctgca
    50341 acaggattcc atgaacgtcg tggaaccgtt caaggctgcc attccttaca aatcggtcat
    50401 tgacctcgag gagaagaaaa acgtcctcat catcaccgtc aagggggacc cgcccgtcat
    50461 ctacaggatt gccagcgtgg aaaaggtcct ccaggcaatg aaacgcttca ttgcgatgtc
    50521 ctgcagcgcg tacaggctga tggcatattt catgtcgcct gcagtccggg gcggggtgat
    50581 ggtcacgaat gcaacatggg agaaaggggc cattgctgtc ctgaaatcca ccatctggtt
    50641 cgtcagccag aacaagcagg tctccgttgc ccttaaagaa gtcacaagca tggagatcac
    50701 aaagaaggag gtccagaaga accaggtgga cgtcctgaaa ctggaccaca tggaaaatac
    50761 agacgtggtg acgagttacg tcctgtgccc cctgtccaca ctgcaaatcc tcataaactt
    50821 cctcaaggat gcgacaaagg acctggaaat caccggtgag gaactggatc ccgtcgcagc
    50881 ccaggtcggc atgctcatct acagcgggat ggactcccat gccatcgaaa aaatgctcaa
    50941 cattccctac aagaacctgg acgaaattta cgaaaagctc ttaaaactcg ggatggccga
    51001 ggtaacccag gtcaggaggg aggtccagct cacacccaag ggcgtccgtt tcatcacgga
    51061 atccgtaaaa ccccccacgc agtagggaga gggcattcct gaccggtccc caacattaaa
    51121 tatataaatt cttcggaatt acctgtatag tggtatatat ggggagaatt ctgatagtgg
    51181 acgatactct cttcatgcgc acactcctga agaatatcct cttttccgga gggcatgaca
    51241 tcgttggtga agccggcgat ggagacgagg ccattgccaa gtaccaggaa ctcaagcctg
    51301 accttgtcac aatggatgtt gtgatgccca aggtcaacgg aatagaggcc ctgaagggga
    51361 tacgggcgat cgaccccaac gcgaaggtcg tcatgtgcac ggccgtgggc caggaacaga
    51421 tggtcaagct tgccatcaag acaggtgcaa aaggctacat cgtcaagccg ttccaggctc
    51481 ccaaggtcct cgaagagatc aaaaacgtgc tgagttcatg agacgatgat ccgggttctg
    51541 gtcgttgatg attccctgtt catgaggacc atgatcaggg acatgctgga aaaggacccc
    51601 gaaatcgagg tagttgccac tgcaatcgac ggcgtggatg cactcaagaa gatcaacgag
    51661 tatgcgcccg atgtcatgac ccttgacatc gagatgcccc ggatgaacgg gctcgaagtg
    51721 ttgaaaagcc gctccaaggc agcagctttc ccgaaagtcc tgatgctctc ctcactgaca
    51781 tcggaaggtg cggaaatgac ccgggctgcg atgatgcttg gggccgatga cttcatgctc
    51841 aagccaaagg atatcagcgc cgtgaggggg atcgggaagg aactcattga caaggtacac
    51901 aacctcgtca gtatcgccta tgtcaggagg gtggaaaagc cacccgaagc gcttgccgac
    51961 aggctcgtcg tgattggagc atcggcaggt ggtccgccca tgctcgatgt cctcctctcg
    52021 tcgatggatt ctcccatccc tgccgcgatg gtcatcaccc agcacatgcc cgagggaggg
    52081 tttaccgctt cgctagcgac aaggctgaac aggatctcac ccatgccggt gaaggagacg
    52141 gagagcgggg acgttctcct gcggggaaac gtctacatct ccaagggtgg ataccacacc
    52201 atcatcgggg cacacgttgg ggagaatggc gtgaaaggtg gtcgtatcat ccattcgcag
    52261 tccccccctg tccacagcgt ccgcccggcc gtcgacagga cgtttacgtc cgctgcaacc
    52321 acgttcggtg acaggacagt ctccgtcatc ctctccggga tggggtcaga cggaggggag
    52381 gggatggccg ccatcaagca gcatggtgga aagactatcg tctgcagtga ggaggactgc
    52441 ctcgtgtatg gcatggcacg gtcggccctt tcgcggaact gcgtggacaa ggtcattcca
    52501 ctgaaacaga taggaaaaga gattgccagg gtcgtggcag ggatggtgaa ctgaaggctt
    52561 atgtcagaac tcgatgcata caggtccctc tacatcgcgg aatcacggga aaaccacgag
    52621 aatatcgtga aacacctcct ccttctcgag acggaggcgt ccgagactgc tattgccgag
    52681 atattccggt ctgcacactc cctgaagggg atgtcagcat ccatggattt caagggcatg
    52741 gaacgcctct gccacgcgat ggaagacgtc ttccaggaga tccggaacgg gaaacttgcc
    52801 gtcagcaggg aactcatgga ctccctcctc gtcgcatcgg accagataga ggcaatgctt
    52861 gacgacatcg aatgcggggg tcccggaatt cctccaaatc tcgacgatct cgagaacgag
    52921 ctgaaaaggt ggattggaaa aggagggatc agggggggac cggaatccgt gactcctccc
    52981 gctgcgggag atacctctgc acccggagca gaatctccgg atatgcctgc gggagctccc
    53041 cggtactccc ttgcaatcca gctgaccgat acctgtgaca accccaacct cagggccatg
    53101 ataattctcc agaacctgga agaggtaggg accattgaga gagtcatccc tgaccgttcc
    53161 gttgtcgagg atggagagtt cggccgcagg ttcgaagtcg agatcaccag cgatgccggg
    53221 attgacgccc tgaagacaat cgcaaccacg acagatgtcc tgtctgcaac cgttacggaa
    53281 ggaggaagga agacccctgt acctgcttcc ccgccagccc ccgtccaacc catggagaaa
    53341 gaggatatca ggaccgcaaa acagcctgaa aaggtggaga agagccgcga ggtcaagaat
    53401 atcagggttg acatcagcag gctcgactcg atgatgaacc tcgtggaaga cctcgtcatc
    53461 aacaggggac ggatcacgga gatagcgcgg ggccaccaga taaaggagct ggacgagacc
    53521 cttaacatga tcggcaggtc agtttccgat ctccaggcac tgatgatgga tatccggatg
    53581 atccccctct cccacatctt caacaggttc ccccggactg tcagggacat tgcaaacagg
    53641 gaaggaaagg aagtggaatt catcgtggaa ggcggggaca ctgaactcga ccggagcgtc
    53701 atggatggcc tcaacgaccc cctgctccac ctcatccgga atgcaatcga ccatggcatc
    53761 gagagacctg aagtgaggga ggctgcagga aaaccgcgca aggggacgct cctcctttct
    53821 gcccggagag accgtgacaa cgtcatcatc acgatcaagg atgacgggca gggcatccac
    53881 gccgaaaaag tcaggaaaaa agcaatcgag aagggcctga ttaccccgga ggaggcacag
    53941 gccctgaccc gcgaagagat catcgatttc ctcttccacc cgggattcag caccgcagaa
    54001 aagatcacgg acatcagcgg gaggggagtc ggtctcgatg tggtgcgcac gacgctcgaa
    54061 tctctccacg gcacgataaa agtcgattcc cgggagggtg aggggacaac gtttgaactc
    54121 ctgctgcctc ccacgatggc aatcgtcaac gtgatgatgg tcaggatcaa cggacgcagg
    54181 tgcgcgatac ccatccacaa cgtcgtggaa gttgcaggcc ttgacaccgg aaacatccac
    54241 accatcgggg gcagggagac gatcctcctc cgggacgagg taatgcccct tgaccggctc
    54301 gatgacatgt tcggacgttc acctgcaacc gagatcctcg tcgttctcca gcaccagaac
    54361 aggaagagga cgattgccgt cgacgagatc gaggggcagc aggaggtcgt gatcaagcca
    54421 ctctccaagg tggtcggaac ggtcaggggc atctcgggcg ttaccatccc cggtgacggc
    54481 gaggtggtcc cggtcctgga cgtgaactcg atcgtatctg aaacgtgaca aaggagaaac
    54541 aagatgctca acagccagca atcagacgcg ttgagggaac tggggaacat cggggcggct
    54601 catgctgcaa caaccctctc cacgatgctc atgaccaaca tcgagatgga ggttcctgag
    54661 atcaacgtgg tcgatattgg aaagatccat gaacacgtga gcgacgagca ggcagccctc
    54721 gtcatattcc agatccaggg ggaagtctcg ggcggcggct acgtgctcct gcacatcccg
    54781 aagaactctg ttgtccggtt gacaaatgca atgctcggga tgacggaact cgacagggaa
    54841 ctgaccgaga tggaccagag tgctctcctc gagattggaa acatcatggt ctccgcgttc
    54901 ctcgatgcaa ctgcgacgct cctgtccatc gtgatgctcc cctctccccc gtccctcgtc
    54961 atcgatatgc cccatgctgc attcgagtcc atcctcgcag cccaggacta tgcccagatc
    55021 gaccaggtcg tcatattccg cacggaactg cacagtgacc agtacaagat ctcgagcaac
    55081 ctcttcctcc tgcccaacaa gccgatgctg gacgaaatca tcgggatgct cgagaacctg
    55141 atgaagtaac ggggaaatga tgccgggccc tgaagaacag gtcgtgatgg tcgggattgg
    55201 tgaataccat atcgggagat ccccgatgtc ctccatcggc cttggctcct gcatagggct
    55261 cgtgatccat gacccggtaa atgatatcgg ggggcttgcg catatcatgc ttcccgattc
    55321 gcagggacgg actgaccgcc cggcaaaata tgccgatact gccgttgaat tcctcatcag
    55381 ggggatatgc cgccagggat cgaaaccgga tggactcgtc tcaaaaattg tcggcggggc
    55441 ttccatgttc cagtcgttct ccggcaacct caacatcggg gaccggaaca tcgaggctgt
    55501 gaaaatccag ctgaaaaaat tcaatatcag gatcgtcgca gaggacacgg gcggaatcca
    55561 gggccgcaca atcgtttact atccggagga aaagggaaaa atcagtgtga gaactgccga
    55621 tggaaatata aggttcatct aattcctgtt ggtgataaag acagcggcag caatcacggt
    55681 tgtccacagc ccgttcttgt ccccctgcgc tgactggcat atctgcgttg tcttgatgat
    55741 ctttccgctt gccttgtaga tctgttcccg ctcctgccat gccttgttga tatcgaattc
    55801 gataccgagg gtggtcgcaa gcatcgtggc tgcaaggtct tccgcataat ctcccgtttt
    55861 ctcggcagtc tccccatatg catggtgctc cgacaggtac ccgtactctt ttgcatcctt
    55921 gggcagtgca aggccgattg cagctgatat gaggcggttc ggctcattcg tgtcgttctt
    55981 tgccatcacg cagtatgtta tctcccctgg ttcgagcatg cggcaaccct cctccacaga
    56041 gactatcttg cagttgggag ggaagatact cgacacgtag acaaggttga acttctcgat
    56101 tcccgccttg cgcagcgcaa gctcaaagga ggcgagcctg tccctgtgaa cacccacccc
    56161 cttcgtaaaa aacaccctgc ttggaacgac catattattg aatttatcac attctggatt
    56221 atttaatttt tttatttttc aaaaaaatgg tttaatacat tctaatttta attctaatag
    56281 agaataaacg ttaaaaggga gaaaaacggc gataatggtg ttttgaatgc cctaaaaaaa
    56341 gtgacccccg tttttcccat cttctttcaa taacatcata tttttaaaat ccggggtcaa
    56401 aaacagggaa aaccaccaaa agtttatata gtaagatggt caaccgggaa aaggctggag
    56461 atgggatcat tccaaaaaca ggaaccattt ttacctgtat ttgtatctgc gctctcctct
    56521 gtgccattcc tgcgaccgtg agatcggata cccctctccc ctgtaaattt ttcggaaagg
    56581 tcacactcta cggcagtcct gcaccgccgg gaacaatcat cactgccacg gttaacggga
    56641 acgtgagggg gagttacacc acaacggaat ggggcaaata tgccagcgac tgcatgtttg
    56701 gaccaaaact cgttgtccag cccctcggag aagatcttgc agcaaatgac ctccttttga
    56761 tcacattctt tgtaaacggg cagccggcag atgaaaccgc tttttatttc cccggtgcca
    56821 cgaggtggct tgacctctct gtcacccgca ttccgacacc gactccaaca ccttcaccga
    56881 caccaactcc cgcacctact ttgacaccga tacctacacc aacacccagt ccgacccaaa
    56941 ctccttcccc cactccgacg cccgtgccca caccaatgcc cctgcccgtt gcgcatttca
    57001 attgcacacc ggactttggt tattcccctc tcatagtctt tttcaccgat ctgtccggcc
    57061 agaacgtgac atcgtggtca tgggactttg gtgatggcaa tacatcgggt gaacagaacc
    57121 ccgtccatac ataccgccac cccggcaact ataccgtgaa cctgactatt gagtcagata
    57181 caggatattc ttcctccatt atccctgatt gcgtcgttgt ccttgccccc tctctcattc
    57241 ccttcccgga acaggaaaac ctgcccggtg atccggatga cgacggctat tacgaagacc
    57301 tgaatgggaa cgggagaact gatttcgacg acgttgtcct ctatttctcc tatatagact
    57361 ggatttcgga aaacataacg tcaaatccat tcgattacaa ccagaacgga cgcctggact
    57421 ttgacgacct ctcctgcctc ttcctcgagg tctgatagat catcagggct actgtcacct
    57481 ttttgtcccg ccctgccttc cggtcagtgg aaccgattca aaaaacacgt ggaaaaaggg
    57541 tgattgggtc ttcctttctg cttcccgaca catattaaaa ccaatcccgc ataccatata
    57601 tggaaaccat gaaggcggtt ctgggcctcg aggacggcac gtgcgtggcc ggcaagggat
    57661 ttggtgtgga gggggaatgc gcaggtgagc tcgttttttc aacccagatg agtggctaca
    57721 tggaagcact cacggaccca agctaccatg ggcagatcct gatgttcacg tttccgacaa
    57781 tcgggaacta cggtgtcgac agggcgaact tccaggctga acgggtctgg gcgcgcgggt
    57841 gcgttgtccg cgaggtctgc gatgttccgg aagtcccccc ctcgctctcc actttttttg
    57901 cggaaaacca cctcctcggg atccagggag tcgacacccg catgctgacg atcaagacga
    57961 gggtggaagg gaccctccgg gccggcctcg tcgtggggaa cgatgactcc gaaagggccg
    58021 ttgaactagc gcaaaagaca cccccgctgt cccaggtgga tctcatcccc gatgtctcct
    58081 gcaggcagcc ataccacata ccgggaaagg gaaagaggat cgccttcatc gatctcggac
    58141 tcaagaagaa catgctcgtc agtctccggc acagggacgc tgatatcttc gtctatcccc
    58201 atgactgtac ccctgaccgg gtgcttgaat caaagccgga tgcactcttc atcagtaacg
    58261 gtccgggtga ccctgtcctc gcgacgcatg cgatccggtg cgtcaaggaa ctggctggca
    58321 cgctccccat atacggcata tgcatgggca atcagatctg cgccctcggc cttggggcaa
    58381 aaacctacaa gatgaagttc gggcaccggg gcacgaacca gcctgtccgg tacaaggacg
    58441 ggagcatcta catcacgacc cagaaccacg ggtacgccgt cgatgccgat acactccccg
    58501 aaggatcgta cccgatttat acaaacgtca acgacgggac cctcgagggg ttcgaggacc
    58561 cgtacctcga catcacctgc gtgcagttcc atcccgaggc gcacggggga ccgagggaca
    58621 cggagattcc tttctttgac acgatgttcc ggaggctctc ctgatgccca agaaagccca
    58681 tatcaggaag gttctcctga tcgggtcggg gcccatccag atcgggcagg ctgcagagtt
    58741 cgacttttcc ggatcgcagg cctgcagggc gctgcgtgag gaaggcgtca gggtcgtgct
    58801 cgtcaactcg aaccctgcga ccatccagac agatcccgag atggcagacg agatatacat
    58861 cgaacccatc aaggcagaca tcatcgagaa gatcatcagg aaagagaagc cggacggcat
    58921 tctctcgggc atgggcggcc agacgggact caacatgacc gccgaacttg ccgagcgcgg
    58981 cgccctgaaa ggggtcgaaa tcttaggaac acccctcgag gcgatatacc agggagagga
    59041 ccgggagaag ttccgggcac tcatggagag gataggcgag cctgtcccgc ggagcatgat
    59101 cctcaaccgc ccggaccagg tcgaggaggc cctcaggact gtggggctcc ctgcgatcat
    59161 caggcctgcc tatacccttg gagggtcggg tggcggcatt gcccatacca gggaagaact
    59221 tacccggatc atcgagatag ggctgacccg gtcgagaata caccaggtgc tggtcgaaga
    59281 atcggtcgtc gggtggaagg agatcgagtt cgaggtgatg cgcgatgcgg gagatacctg
    59341 catcatcgtg tgcggcatgg aaaacgtgga cgcaatgggt atccacacgg gagagagcgt
    59401 ggtcgttgca cccatcctca cactccggga cgacgaattc cagaccctgc gcacggctgc
    59461 catcaagatc atcagggcgc tcgatgtcca gggcggatgc aacatccagt ttgcctaccg
    59521 ggacggcgag taccgcgtca tcgaggtcaa tccccgcgta tcccggtcgt cagcccttgc
    59581 ctccaaggca acggggtatc ccatcgcgcg ggtggcggca aaaatagcca tcgggctccg
    59641 cctcgacgag atcacgaaca gtgtcacagg gtgcacaccg gcatcgttcg aacctgccat
    59701 cgactacatc gttgtcaagg tcccccgctg gcccttcgac aagttcagga atgcagaccg
    59761 gacactcacc accgccatga agagtaccgg cgaggtcatg gctatcggga ggaccgtcga
    59821 ggaagcattc aagaaagcac tccggtccct cgataccgac atggagaccc atacaagccc
    59881 gcccgagata cgcatgatcc tctcccgccc cacagacgag aggttccaca cgctctttga
    59941 cgcagtccgt gccggttttt cggttgcaga aatctcagaa atgacgcata tctctccgtt
    60001 cttcatcgaa aaggtaaaga acatcgtgga catggagaag cggctcaggg agtctgccgg
    60061 gaaggatgag atcctgcttg caaggaggta tggtttttcc gcatccgaga ttgcatcact
    60121 gacgggcctt tcccccgacc gggtaaggga gattgcgggt gatccgacct acaagatcgt
    60181 ggatacctgt gcagcagagt ttcctgcccg cacaccctat ttctactcga catgggatac
    60241 cgagtgcgag attccaagaa cagagcggca gaaagtcctc atcctcggtt cagggcccat
    60301 ccgcatcggg cagggtatcg agttcgatta ctgcacggtc catgccgtaa aggcccttcg
    60361 tgaggagaaa gtcgaggtcc acatcgtcaa caacaacccc gagacggtct cgacggattt
    60421 cgatacctct gaccggctct tcttcgaacc catgacgctt gaggatatca tcaacatcct
    60481 gcagaaggac acctacatgg gtgtcatggt ccagttcggc gggcagaacg ccgtcaacct
    60541 tgccgtgccc ctgcaggagg agatgcggag gctgggactc gcgaccaggg tgctcgggac
    60601 atcacccgac tccatggata ttgccgagga ccgcgaccgg ttcagcatcc tcctggacag
    60661 gctcgggata ccaagcccgc ccaacagttc cgcgtattcg ctcgaggagg cacgggaaaa
    60721 ggccgcggcc atcgggtacc ccgtcctcgt ccggccttcc tacgtgcttg ggggccgggc
    60781 aatggagatc atccacgacg agatcgagct tgaaggttac atgaaggagg ccgtgcgtgt
    60841 cagcaggaac cacccggtac tcatcgattc cttcctccag aacgcgatcg aactcgatgt
    60901 cgatgcggtc tgcgacggat ccgaggtcct catcggcggc atcatggaac acatcgagga
    60961 agcaggagtc cacagcggtg actcggcatg cgtcatcccg acacagtctc tttcgccttc
    61021 catcattgag accgtgaagg agtatacccg gaaaattgcc cttgcgctcg gtgtcgtggg
    61081 ccttatcaat atccagctcg cggtcaagga cggggtcgtc tacgtgctcg aagcgaaccc
    61141 ccgggcgagc aggacggtcc ccttcgtgag caaggcaacc gggataccgc ttgcaaagat
    61201 agcggcaaag gtcatgatcg gaaaaaagat aagggacctt gggtacgtcg aaaagccctt
    61261 ctcccacgtg gccgtcaagg aagtcctcct tcccttcaac aagctcccgg gcgtggacac
    61321 ggtgcttggt cccgagatga agagcacggg agaggtgatg ggaatcgact acgacttcgg
    61381 ccgtgcgtac tacaaggcct gcgtatccgc cgacaacaca ctgccgctcg agggcaatat
    61441 cttcatttcg atctccaagg atcaaaaaga cgaggtcatt ccgattgcac gcaagctcca
    61501 cgagataggc cttcgcctct tcgggaccgc gggaaccgtg gaatacctca acgatgcagg
    61561 catccccgcc cagcacgtca ggaaggtgca ggaagggtca cccaatgcga tcgacctgtt
    61621 gcggcgtggc gagatccggc tgatcatcaa cacgccgacg gacaagcagt cgcggcagga
    61681 ccattaccag atcatgcggg cggccgtgga ctacggtgtc ccctacatca cgaccatcca
    61741 ggccgcccgg gctgccacaa tggcaataga ggccatgaga aaggaacaga tcaccatcga
    61801 gcctctctcc cattacatcg gggagatgtg attcgcaggg ccttttccct tttcaaactt
    61861 tttttgccag ggagtcgtgt gatatttttt tgccctgaaa tagccttatt accgcgcagg
    61921 gggcaatgaa taggtattgt ccctccaaag gactggcagg agtgcatgaa aaatgggaaa
    61981 gggaacagtt gtccttgcct attcaggcgg tctcgataca tcgatatgca tacccctcct
    62041 ccgggaacgc tacgggtatg accgcgtggt caccgtcgcg gtgaacgtcg ggcagcgcga
    62101 tgaagagata acgaccgcga cagagaaagg ccacaagctt gccgataaac attacaccat
    62161 tgatgcccgc gagaagttcg tcaccgggta cattctcccg gcaatcaggg caaacggctc
    62221 ttatgaagga taccccatgg gtacggccct tgcccgcccg ctcatcgcgg aggaagtcgt
    62281 caaagttgct gcccgggaag gtgcccacgc cgttgcccac ggatgtaccg ggaagggaaa
    62341 cgaccagctc cggttcgact ttatcttccg gatggcagga ctcgacgtga tcgctcccat
    62401 ccgcgagctc aacctcacgc gtgactggga gatcgattat gcaagggatc acggcatccc
    62461 tgtcccagtc gggaaggaga ggccctggag cgtggatgaa aacatctgga gcaggagcat
    62521 cgagggggga atgctcgaag accctgcctg tcaccctccc gaggagatct atgcatggac
    62581 cgtctctccc gtcaatgccc cggacaagcc cgagatcctt gcgatcgact tcatcaaggg
    62641 gattccccac cggctcaacg atgtcgagta cgcgcccttt gacctcatca gggaattgaa
    62701 tacccgggca ggccggcacg gcatcgggcg gaacaacatg atcgaggacc ggatcctcgg
    62761 gctgaaggcc cgcgagatct acgagcatcc cgctgctacg gtgctgctcc tcgcccacca
    62821 cgacctcgag cacctcaccc tcacccggca ggaactcgca ttcaaacatg tcgtcgacga
    62881 gaaatggtcg gaactcgctt acatgggtct cgttcacgaa ccgctcttcc acgatctctc
    62941 tgcgtttatc acacagtccc aggagagggt cacggggagg gtcgaggtac agatgttcaa
    63001 gggctgctgc agggtccttg ggcggtcctc gcctgaaggc ctctactcgg gagacctcgt
    63061 ttcgttcgat acgacctcga tcgaccagtg ccacgccatc ggtgtctcgg cttactacgg
    63121 aatccaggcg cggctggcag agcagggaaa gaaggggagg aagtaatccc actcctcact
    63181 ttttattctt tgccactttt ttcggatctc ccgggctctg cccgccgggg cactggcatt
    63241 tagagtgcca aaggtattct tatccggact tgtgaaggca ggagttcccg cctgtccctt
    63301 gcccacaaag agtcgtgaat aggaaaattg aggagactaa ccaccgggaa caagcaagaa
    63361 agagtggggg gtttaaagta acttctttcc ggcgtgcgga ccggggttgc attcatagac
    63421 ttccgtgatc ttcatcacga ggagggattt tgcggggaga tccggtttct tctcgtggac
    63481 catcttcttc atcttctcat agtcgggtcc cgaagtcttg acctccactg tccccttgat
    63541 ctggaagcac ttctttgcat ccggatccca gatgtagatc gctgcatgcg gattctcctt
    63601 cacgtttgca agggtcttgt gcatgaaatt gtccgcgagc cagagggtgt catcggcagc
    63661 catgatcacg aatgcgatcg gtgcaacgtt gggaacgccc ttttttgaag cggttgcgac
    63721 cgggaagagc ttgatcttcg caaacgtctc cttcatctcg ggtgtcaggt ttaccatttt
    63781 ctcattcacc tcgttatttt gaggattaac agcgtgacag tgccgttact actccagtat
    63841 gtttctctcc ccatattctt tttgggaact gccacccgat gacatcatga agagaatcat
    63901 cgtaaaggag tgacaagaga ccatcaatgg cgggcacacg cgaatgcgaa ccatcctacc
    63961 tctccttgca ccggtccggg gaactggacc ggcgtgtgga acgtatccgg gagctgctct
    64021 ccccctgccg cgtctgcccg aggcggtgcg gtgttgagag gatccggggc gagactggtt
    64081 actgcggcgg cggccttctc cccaaaatat cctcttatgg tccccatttc ggggaggaac
    64141 cacctctggt gggggtttat gggtccggca cgatcttttt cgcggggtgt tccctgcggt
    64201 gtgccttctg ccagaactac gagatcagcc aggagcggta tggcagggaa gtcagctgcg
    64261 aggaactggc gcagatcatg ctccggctcc aggacagggg gtgccacaat atcaacttcg
    64321 tcactcctac ccacttcgtc ccccagattg tccggtccgt atccattgcc gtaaaacagg
    64381 gccttgccct ccccctcgtt tacaacacgg gcacgtacga ttcggtcgaa acgctgcgcc
    64441 tcctcgatgg tatcttcgac atctacatgc cggacgcaaa gtatgcagac aatgatattg
    64501 ccatagcact ctcggacgct ccccggtacg tgaatgtcat ggaggaggca atcctggaga
    64561 tgcagcggca ggccggcgac cttgtcatgg acagggggat tgcaaggagg gggcttatta
    64621 tccggcatct cgtcctcccc ggcgacctcg ccgggagcgg gcgcatcctc gcattcattg
    64681 cagaaaaggt atcgcgggat gcctacgtga acatcatgga ccagtaccgc ccctgcggga
    64741 gggtcgggga ccttggggca gatccgcgtt ttgcagttct gaacaggagg ctgaccgccg
    64801 gggaatacga gagggcagtg agtgccgcac ggagagcagg acttcaccgt ggaattccgc
    64861 tcggaaactc gtgaaggaaa gagacgcccc ggccgggact tgaacccggg tcaaaagctc
    64921 cgcaggcttc taggatatcc actaccctac cgggacgctg gctataatta tctcgcacgg
    64981 atgcttaaat agttcacctt ttctccctca cctttccgga gtttggaaag aatagcccca
    65041 tcagtcattt gaagggaacg aggtgcaatc gtagagattt ttataataat atcgagatga
    65101 ttaaatgtcg ggatcataca tacttgatgg tgaaaccgcc agccagggaa tcctttggat
    65161 gtcggggggc tttcccccta atgatggata tctgggcagt cctttaagat ctcattacct
    65221 gcacaaaatt gtgaagaacc gaaaagagaa gacatccccc tcattttaag gtaaagggca
    65281 gttgcattcg tatctttata ttcttccatg acttcggaga tgttaatcaa atgaagaata
    65341 gtcgtcgtct acaaaaaaat tccaagaatc ccaccgtcga tgcgtttttt tccggaaccg
    65401 cggcactatt cccattcccc tgttaaggga aagcggcccc gcatctgttc ctcacgactc
    65461 catacccata acacggggcc aggaatgaga ttgaaccgga taagaaaata tatgctccct
    65521 cccgcgcaaa tatctctcac ctttacgggt tgtaccatga aaaaagcctt gataaccggg
    65581 attacggggc aggacggctc ctaccttgcc gagctcctcc tctcgaaggg atacgaggtg
    65641 cacggactcg tccggcggtc gtcctccctc aacacgagcc ggatttccca catcttcccc
    65701 gaggccgaga tagccgggac agcgtcgagc ggctcgggac ttttcctgca ctacggggac
    65761 ctctcggact ccgagcaggt atcgacgatc atggaccgcg tccgccccga tgagatttac
    65821 aaccttgccg cccagagcca cgtcagggtc agttttgaca ctcccgagta cacgggcaac
    65881 atcacgggcc ttggcacgac ccgcctcctc gaggctgccc gccggagcaa tccaggcgtc
    65941 cggttctacc aggcatcgag cagcgagatg ttcggcggtt caccacctcc gcagaacgaa
    66001 aatacagctt tctatccccg gagcccctat gcctgtgcaa aggtctattc ctactggatg
    66061 acgcggaatt accgggaagg gtacgggatg tttgcatgca acggcatcct tttcaaccac
    66121 gagtctcccc ggcggggcga gaccttcgtc acccgcaaga taacccgggg catcgcaaag
    66181 atccttgccg gaaaggaaaa gatgcttgcc ctcggcaacc tcgatgcaaa gcgggactgg
    66241 ggatattcgc ccgagtacgt cgagtgcatg tggctgatcc tccagcagga gaagcccgac
    66301 gactttgtca tcgggacggg agagacgcat tccgtccagg aattcgtcga cgcagcgttc
    66361 cggtatgccg gcctcgacag ggacgagcac gtcacgatcg accagaagta cttccggccg
    66421 acggaggtgg atgtcctggt cgcggacccc cggaaggccg aaaagaagct cggctggaag
    66481 gcgagggtgc gctttgggga cctcgtgaag atcatggtgg atgcagacat gagggcgttc
    66541 gggcttgagc ccatcggcga gggggacagg atcgtggaga agaggtttgg ggagaaatgg
    66601 tggaaggggg attgaggggg aattccctaa taggttacga aggtgtatcc ctgcaccaat
    66661 gaatcatttt ttccagtccc tctttcaagg gaacttcggg ggtccaaccc agcactttcc
    66721 gggcctttgt gatatccggc agcctgcggc gggggtcatc cggaggttgg ggatggtatt
    66781 caaaccgggg ttctgatccg tggatttctg cgatgcatcg agcgagatcg aggattgaga
    66841 cttcttccgg gttcccgatg ttgatgatat ttcccgcaag gcctggacgg gagataaacc
    66901 tgattaaacc tctgacctga tcagtcacgt agcagaaact ccgggtctgg agcccgtctc
    66961 caaaaattga aaagggttct ccctgcattg cctgggttat gaaccgtggt atcacccgcc
    67021 cgtaaatccc gtcggacctc atccgcgggc cataggtatt gaagatccgc acaatccgtg
    67081 catccgtccc gtactgtcgg taatatgcca tgcagagcgc ttcacccgcc cgctttgcct
    67141 cgtcgtagca cccccttatc ccgacagggt tcacgttccc attgtgtgat tcgggggtag
    67201 gaaagacaga ggcatctcca tagacttcgc tcgtgctggt aaagaggaga gtcgcaccat
    67261 ttttccgggc aatttcaagg gcattcattg taccgagggt atttgaccgg aggatgtcaa
    67321 tcgggtggtc ggcaaactcg agaggcgatg cacgggatgc aagggcgagg atataatcat
    67381 atcccccatc cggattgaat ggggctgata catcctggta caggaaggaa aatccgggat
    67441 ccttcttcag atgccggata ttttcttccc gcccgctggc gaagttatct atgcaggtaa
    67501 cggatgcgcc gaggcgaagg aatgcctcgc acaaccacga tcccaggaaa cctgccccac
    67561 cggtaatcaa tactctctgg gaattgaaat catgcaactc cctgtcgtcc aaaattcttt
    67621 ccaggtcttt gctatagtct ttcaacgcga atcaatccct caccagctgt ttcatgaaag
    67681 cggccagttc atctgcaaat tcatccctct ggagtgataa ttcgatgatt gtcttcaacc
    67741 accccatttt atccccgata tcgtaacgag tacagtgagt cacgagtccg atggggttat
    67801 cgacacgtcg cagtgcatcg gtcagctgta cttcgccgtt gtagccgggt ctggtgtttt
    67861 tcaggatatc aaagatatca ggggtaagga tgtacctgcc gattgcaccc aggtttgatg
    67921 gtgcgttttc cggcaggggc ttttcgacaa tgtcggtaat ggcataggca ttatccgaaa
    67981 tcctgtgtcc atcaatgatc ccgtagtccc tgatcttttc aggtgggacc tcctctacaa
    68041 cgatgatggt cgactcatac ttcccaaaag cttgaaccat ctgggtggtg cactctggct
    68101 gcccggcatg ggggattgta atcgtgtcac ccagcaacac tgcgaagggt tctccgtcgc
    68161 aatgcttttg ggcatgcaga attgcatcac ccagccccct gggatgcgac tgccgtatgt
    68221 agtggatatc agcaatgcca gagagatccc ggacttcctt gaggtggcta tggtttttct
    68281 tttctgcaag gtgcgcttcg agctcaaaag aagtatcaaa atgatcctcg attgccctct
    68341 ttccccttcc cgtaatgatt aggatatcat cgattccaga agatacggcc tcttccacga
    68401 cgtattggat gaccggcttg tctacgaccg gcaacatctc cttgggctgg acctttgttg
    68461 caggaagaaa ccgtgtccca agacccgcgg cagggattac tgcctttttc actttccggg
    68521 atcgctgtgt catattacaa ctccaaagga acgccaaaat gcatcgatgc tggtattgta
    68581 ccttgttgga gtatgcgaga aagacgattc atgcttttct ctgaaatgtc caaccgggca
    68641 cacttgtact ttccctttca tcgcccgttt accagcaaat cccttcatac ccatgtgttt
    68701 tcaggaccct ccggccttca atgatcaccc tattgttcat taagtcaaat tccttgtcga
    68761 gccgtgagaa ttcgggccat tcagtcagga taagacatgc atctgcacct tcaaggacgg
    68821 cctccggtgt tgttccatag tcgatgtcag ggaatacctc cttcatggca gggatggcaa
    68881 ggggatcata ggctgcaaca tgtgcccccc tttcccggag cattcgtatc acgggaatcg
    68941 cccgggattc cctgatgtca tcggtattgt ccttgaaagc aagtcccagg acggcaatcc
    69001 tttttccatg gaggcctccc accctctttt cgagaagcga gatcattttt cccggttgat
    69061 cctcgttgac cgaaagaacg ctcttcaata tgcagggctc aacacccatt ccctcggcga
    69121 accgggcaag cgccatcacg tccttgggaa aacaacttcc cccgaaaccg acaccggcat
    69181 tgaagaattc cttgccgatc ctacgatcca gtcccacacc ttccatgacc ctgtagacat
    69241 caatgcccat tctcttgcag atattgccta tttcgttgga gaatgagatc ttggtcgcaa
    69301 ggaatgcatt ggagacgtac ttgatcatct ccgcctcggt tgggagaacc tggatgacag
    69361 gggcctcgat tccctggtac agtcttttca tgcaatcaaa caggtcctgt tcatggcacc
    69421 cgatgacaat cctgtcggga tggaaaaaat cccaaaccgc acgtccctct ctcaagaatt
    69481 cagggttcat tccaaaggca atgttttccc gccctgcttc tgaaaggacg gtttccctga
    69541 cgaggccatc cgtggtgccc ggagggacgg tgctctttac aacaacatag tgttttttat
    69601 cctgattcct gagagctctc cctacagatt cagaagcgct tcttacatag tgtaaatcgg
    69661 cattacctga attatccggc ggagtcccca cgcaaatcat tgtcagttct gcatctttta
    69721 caggaaaaaa ggaacatgtt gcggataaat tcttcccgat atgtttttta acaatttctt
    69781 ccaatcccgc ttcaaaaaga ggaggttttc cttcattgat tgaaaggacc ttcttttcat
    69841 caatatcgat aataacaaca ttgtgtccaa gttcagccag gcaggaccct gtcacaagcc
    69901 ctacataccc tccgcctatg acacaaaccc gcatctatgt ataatttgag gtaaaataag
    69961 attaaaatga tctttgattt catggagata cacaaaccgt t
//
LOCUS       DAOOJU010000007        59647 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_594_length_59647_cov_12.961102, whole genome shotgun sequence.
ACCESSION   DAOOJU010000007 DAOOJU010000000
VERSION     DAOOJU010000007.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 59647)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 59647)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59647
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_594_length_59647_cov_12.961102"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            12..755
                     /locus_tag="PK679_03125"
     CDS             12..755
                     /locus_tag="PK679_03125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase sliding clamp"
                     /protein_id="HPC54983.1"
                     /translation="MLKATIDADILKESIDAISALVTECRLHTDENGISTRAVDTANV
                     AMVSLSLKKEAFSSFESTKSELGLDIAKLKNIFGMMGKNEPISLELPDNGQKLRVSFE
                     GYRYSITLLDPNTIRKDPNPPNIDLPGKVVLSGADLYNSIKAAAVVSDKIALGIDPAQ
                     QIFYMAAEGDTDHIRKEFGKNEVTFLNNVEARSLFSLDYLKDMGKVMSRAEEVEISIG
                     IDHPVKFAFYIAGGKGYVEYLLAPRIEAD"
     gene            821..1858
                     /locus_tag="PK679_03130"
     CDS             821..1858
                     /locus_tag="PK679_03130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase large subunit PriL"
                     /protein_id="HPC54984.1"
                     /translation="MLRENESLEKFLQRSAGKVALSHAVERVRQAVAFTGPTLPSSSV
                     PELPSDQLGVRLEITSFVLARVLVSCARDRALMERLARYEAQRAHAFLQAEEEEKRIF
                     LAGKIGFPLEGLFLPVPRYIELTAGMHEERWRLVNREVSGGNVLIDPLESEELLREQI
                     RKTLLSSLPLDVPESLCTLLEPCVAGVREEFQKKILRDFGDVEESAFPPCMQAILSAL
                     SGGTNITHAGRFALTAFLHNIGMDTAEIIQVYCRAPDFDISKTQYQVEHISGRGGKGT
                     EYTAPSCSAMRTLGLCVKPDALCGKVAHPLSYYRKKKRLTKGEKPGGGLGDSPVDGNP
                     RTAHREDKDDN"
     gene            complement(1793..1969)
                     /locus_tag="PK679_03135"
     CDS             complement(1793..1969)
                     /locus_tag="PK679_03135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54985.1"
                     /translation="MDARLLDIVCALVCFFLLLALVLTLPAFMAPGSAYLLSIIIFVF
                     AMSGAGIAINRAIA"
     gene            2165..2749
                     /locus_tag="PK679_03140"
     CDS             2165..2749
                     /locus_tag="PK679_03140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate synthase family protein"
                     /protein_id="HPC54986.1"
                     /translation="MVFPHEGYRDMIRMAEPEREEILRTLEEAVRRLVERMDPVLIPE
                     VGSNIAYAMARARSPADVAAVEGRIVRVKGRAHAVGPVAFGASDHVARIVLTAMKFDP
                     DVRCAANIRYTPGLVEACEEMLLSVCSFDRESQPPGVKTMDWGVASCCRDGVPDVIYD
                     RGAVGKEAMIRILGEEPGVVVNNILKLSARIDKD"
     gene            2765..2953
                     /locus_tag="PK679_03145"
     CDS             2765..2953
                     /locus_tag="PK679_03145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17e"
                     /protein_id="HPC54987.1"
                     /translation="MGIKPTYIKAIGMELLTHHGKRFSGNFDENKQTVTEVTNIESKR
                     VRNRVAGYITRKVNTQRR"
     gene            2967..3842
                     /gene="dapA"
                     /locus_tag="PK679_03150"
     CDS             2967..3842
                     /gene="dapA"
                     /locus_tag="PK679_03150"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HPC54988.1"
                     /translation="MFEGVIPAIITPFLRNSTLDLDLDGLRSNIEFLLENGVHGIVPC
                     GSTGESATLTFEEHEKVIEVAIDVAGGKVPVIAGTGSNNTAEAVRLTKAAKDMGADGV
                     LVISPYYNKPNRSGLVKHYTALADLDIPVIMYNVPGRTGQNLPPDLVAELARHPDIVG
                     IKEASGDIGQISRIIEATLDEDFVVISGDDNITLPILALGGAGVISVAANVEPARMVA
                     MFEAFCEGDLEEALDMHYALSPLFRAMFIDTNPIPVKKAVELRGMAGGPPRLPLDELD
                     AEKTKKLAEVLSTYD"
     gene            3835..4611
                     /gene="dapB"
                     /locus_tag="PK679_03155"
     CDS             3835..4611
                     /gene="dapB"
                     /locus_tag="PK679_03155"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HPC54989.1"
                     /translation="MIKVVICGAMGRMGSTVGRLVDAAPDLALVGGVDLKRGEVFGVP
                     VVPAEDMARLLEEKKPDVVIDFTVAPAAVKNVTTAAAHGVALVVGTTGFSADQKAEMA
                     RAIEGHVPAVISSNFSIGVNIFWQLVREAARLLPDYDIEVLEAHHRYKKDAPSGTAKT
                     IIQILEEEVGQRPKLYGREGMMERGKEIGVHVIRGGDIVGDHAVLFAGNFETIQVSHR
                     AYDRSVFAQGAVKATRWVVGKKPGIYSMTDVLSLSAPRSK"
     gene            4669..4842
                     /locus_tag="PK679_03160"
     CDS             4669..4842
                     /locus_tag="PK679_03160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC54990.1"
                     /translation="MTAVVDKDKCTGCETCVDECPAAAISMNDGKAKVDKDLCVDCGS
                     CVDVCPSEAIHLE"
     gene            4890..5906
                     /gene="asd"
                     /locus_tag="PK679_03165"
     CDS             4890..5906
                     /gene="asd"
                     /locus_tag="PK679_03165"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HPC54991.1"
                     /translation="MIRVGVLGATGAVGQRFVQLLAQHPWFELAALTASDRSAGKRYG
                     EVVNWRLDVPFPKEVADIPIRTTETKSLSDVDLVFSALPADVAGPVENACADAGIAVC
                     SNASSHRMDPLVPLVIPEVNPDHLALIDAQRDAGRDGFIVTNPNCSTIVMCLSLAPLR
                     KFTWTDIRVATMQAISGAGFQGVPAMGIYDNIIPYIGSEEEKMETESLKIMGSLDGKT
                     VRPAPFRVSASCHRVPVLDGHTMAIWIDIREPVEEVRKAFTDFSPPVSGLPTLPEKSV
                     VLLDEQDRPQPRLDRNRGNGMTVSVGRVRKGIRYVTMGHNTIRGAAGASVLNAELIHK
                     KKYL"
     gene            5923..6198
                     /gene="albA"
                     /locus_tag="PK679_03170"
     CDS             5923..6198
                     /gene="albA"
                     /locus_tag="PK679_03170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006325 - chromatin organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein Alba"
                     /protein_id="HPC54992.1"
                     /translation="MIKDNTVFVGNKPVMNYVLAVVTQFNNGAQEVSIKARGKAISRA
                     VDTAEIALNRFLEGVNKKQIITSTEVIDTDSGKTNVSSIEIILAATG"
     gene            6487..6930
                     /locus_tag="PK679_03175"
     CDS             6487..6930
                     /locus_tag="PK679_03175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC54993.1"
                     /translation="MTVAVTVVCLLFFIIPVIAVTEDKYGYITVKDMNITLEQGRAYI
                     DIHYTLDEPTRLIVLLLGKQDLKNRLLRILNYEDAEFVHIGMDKASLIVKDVSYNYGR
                     GVYWFPAHRFNIMIPSLRVVTPQTSRIFQATREIPNGIGYFDNPG"
     gene            complement(7050..8165)
                     /locus_tag="PK679_03180"
     CDS             complement(7050..8165)
                     /locus_tag="PK679_03180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004075848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF373 family protein"
                     /protein_id="HPC54994.1"
                     /translation="MQEGRTLILSVDRDDDIGFKANIESPVVGRDACLHAANALGLAD
                     PEDSDINAIFQAVSLYDELKNRGEDVEVAIIAGNHMHMIEGDRKIAASLSEVVARTGV
                     SNCIVVTDGAEDEFVLPIVQSRLPVSSVRRVIVSQIPNLEGTYYIIKKLLNDPKVARL
                     VLVPVGLAMLLWAIAYLMDRPQIATITVVGAIGIYLLYRGLGIDEMFTGFMTALRTSL
                     TRGKVSFSTYIAGILLIIVGIIMGLMSLLVYYAEIGLLLYLLIFMYGAVLWFALAGIV
                     SSIGIIIDNFFYDRDSLAKVIVFPFFIGAVGLIAYGACIYAISMNNIPDFPYDPGTAI
                     EYIFYGTLGGLTCALLGIGVQYYLSRYLSGVKKAGTT"
     gene            complement(8222..9082)
                     /locus_tag="PK679_03185"
     CDS             complement(8222..9082)
                     /locus_tag="PK679_03185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HPC54995.1"
                     /translation="MLNELIEKRKKILAESEQHKNRRNELNALASKWARERNTLNNQT
                     REYVEEAQKNKELRDKYNNEVQSLKDERNRINEEANALFEEIEAFKKEHGGIKNRGLK
                     ELQKQIEHLEFRQQTEVFSTDKERELIEKIKQMKEAMREQEAELEQNKEIKTKIARAR
                     ELRKQASELHAKVTEMAELAQKHHDLMVEFYRKADKSREEADAAHKNFVEAQEAADAE
                     HKFFIACQKELRDYDKVISGLRKKTKKAKVTKEQKAVRKEAEHLFKMFRAGEKLTTDD
                     ILLLQRSKLI"
     gene            complement(9567..10724)
                     /gene="ftsZ"
                     /locus_tag="PK679_03190"
     CDS             complement(9567..10724)
                     /gene="ftsZ"
                     /locus_tag="PK679_03190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HPC54996.1"
                     /translation="MQSIINEALKNAEIEKEMTKTSNSADDDFIGQPRIVIIGCGGAG
                     NNTINRLHHMGVSGAETIAINTDKQHLDMIQADKRVLIGKSLTKGLGAGGYPDVGKRA
                     AEMARPTLEALLENADLCFITAGMGGGTGTGSAPVVAQIAKEQGAIVVGMVSYPFQVE
                     KARLIRAEEGLEALASAADSVIVLDNNRLKNFVPNLPLGQAFSVMDQLIGETVKGISE
                     TITQPSLINIDYADVRAIMSKGGVAVMLVGESKQQNKSESVVRECLSNPMLDIDYRGA
                     TGSLIHITGGGDLTLQDAEEIATSLTYELDPHADVIWGARVKNEMEGKVRVLAIMTGV
                     QTGKIMGSRVSYKTILEDLEQKKGNPKAPQLPRNRKARDQTAGGTLLEWVG"
     gene            complement(10737..10913)
                     /locus_tag="PK679_03195"
     CDS             complement(10737..10913)
                     /locus_tag="PK679_03195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HPC54997.1"
                     /translation="MNRITLRLPDQQIEMLEQMVAIGEFPTVSEAVRAAVRQLIEQRG
                     GRVLQESDQVSFKV"
     gene            11121..12119
                     /locus_tag="PK679_03200"
     CDS             11121..12119
                     /locus_tag="PK679_03200"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HPC54998.1"
                     /translation="MKGQDVEKVIHGGTVIRARKETGARIIDFSASINPYPPELSLSI
                     SREDLSDYPDDTYTELKETIATRFGVSPDEITLGNGSIEILRTFCHCVLLPGDRVGVP
                     SPTFGEYEYSSRLAGAIPGDGARAKVSFLCNPNNPTGHLRTRDDILAFLEKCAASGCL
                     LFLDEAFIEISDDPAQSLAGTIHPNLFVLRSLTKSFAVPGIRFGYGIGHPDLISRLEA
                     FRPPWNVSTVAVKVALEAFARYDELATSGKKIREERAWLCSALRDLPIKIEPSEANFL
                     LIHTGRDVRDLCTRLLRKGILVRDCHSFGLPESIRVAVRTREENALLVEALEACMH"
     gene            12107..12712
                     /locus_tag="PK679_03205"
     CDS             12107..12712
                     /locus_tag="PK679_03205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HPC54999.1"
                     /translation="MYALILAGGMGSRLGLGEKALVTVREVPMIRRVADAFVQAGCDV
                     VAVLSPRTPYTRNWCRANGIFHYVAEGRGYMEDIIEAVTALEISSPVFTCGTDLPLLS
                     SDIVKDLMDRYTTCGMDALSTWVPMALAEEHGYQPPCIGMVSGIEACPAGINILRGDM
                     IASPQEEERVLVADARLACHVNTKSALEIAERLISQSRRPS"
     gene            12821..14059
                     /locus_tag="PK679_03210"
     CDS             12821..14059
                     /locus_tag="PK679_03210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00300 family protein"
                     /protein_id="HPC55000.1"
                     /translation="MQVSREVELEGHIIDSGIMTRVFDTIMDMGGNFEIIVFDVGKKK
                     TDPSYAHLKVNADTEENLNAILSEIHRYGARLLEIRDVVTVPAEGDRVVPKGFYSTTH
                     HPTFVKYAGEWIPVRHIEMDCLIVIDPEKKTALCTPISKLKKGDLVVVGEEGVRVSPP
                     ERPRNVSTFEFMHGTVSPERPSETIIARIAREIIEVKRRGGKIALVGGPAIIHTGAAG
                     ALARIIRNGYIDVLFAGNALATHDIEYNLFGTSLGMDLSTGKPVTGGHKNHLYAISEV
                     IRAGSIAAAVEKGIITGGIMYECVRRGIPFVLAGSIRDDGPLPDVITDAMAAQDRMRE
                     HIRDCSMVLMVATLLHSVAVGNFLPSYVKTICVDINPSSVTKLMDRGTMQAIGVVSDA
                     GTFFPLLEKQLELQSGRING"
     gene            complement(14049..15074)
                     /locus_tag="PK679_03215"
     CDS             complement(14049..15074)
                     /locus_tag="PK679_03215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archaeosine biosynthesis radical SAM protein
                     RaSEA"
                     /protein_id="HPC55001.1"
                     /translation="MSNRRGSPYSTHVAGELNEARPYAAWTGSDRIGNRVLSTLTVIL
                     KTGGCSWNRCRMCSYRHVRLGAAGEGELARLLLAQVSWLKDRFPMDNIDCVKIYTSGS
                     FFDPVEVPGAARDAIGSLVRGKIVIAETRPEFVVTDRVASFREIIDDGSHDLPLYVAI
                     GLETSNDFIREKCINKGFSWDDFLLASKAARSAGAGVKTYLLVKPPFLTERESIEDVV
                     SSINALRGIADMISLNPCSVQKGTELEYYWKRGEFRPPYLWSILTILLRAERHILCDP
                     LSGGRPRGAHNCGTCDRTILQGIRDYSLSGDRGLLEALLGMDCTCKKEWEFVLENERP
                     YCMPLTR"
     gene            15343..16410
                     /locus_tag="PK679_03220"
     CDS             15343..16410
                     /locus_tag="PK679_03220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55002.1"
                     /translation="MVILLLVCTGLVSAYELSISAPPTIQKGKPLVVNGTSNIPAGIS
                     VDIVLSRSEYTTEEIARKTVTLQSNKEFSVVFDTKDLQKGQYKVEVPSIQGYAFLGGS
                     VTLRIVQVVDRSDEVTIKSMRTQEMDGTLEIAGVIPKNPSSGVQVEVVGPGDEVVFGP
                     QFISTSSDGSFSLNVPITKAGRYELSITDSKGFIGTYLFTVNERVETVATLATTPAIL
                     AAITATAPSSAEKPAFFVITGPKGKVKISTSAGTDWVIEYADQRGIIQKVNSKGQVEP
                     EEIAVDVSGDSLFLKVYPYRLSDRGDVTVFVEGAEKIGVATEIPPVFAPTTTPTTKSP
                     LPLLLAVIAFALMALGKRYRS"
     gene            16554..16638
                     /locus_tag="PK679_03225"
     tRNA            16554..16638
                     /locus_tag="PK679_03225"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16588..16590,aa:Ser,seq:tga)
     gene            16838..17668
                     /locus_tag="PK679_03230"
     CDS             16838..17668
                     /locus_tag="PK679_03230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC55003.1"
                     /translation="MSDMESDLKRGMVAWCRRQGIPLVGVADATRWHTPPFVPWMPED
                     FFPQSIFPGTESVVVIGLPVHLPVIETTPSIFYHEHYNTLNRLLDQFTYQIAERFNQA
                     GYPSVSLPRDGYGSIEVLRESPVAFFSHRHAAFLAGLGTFGLNNMVLTQGYGPRVRFS
                     SVFTTARLPPDPLMKIDLCTRCHRCVEMCPARALPEDPYPLGITRKEACTEYSAALFR
                     RHASPCGVCIKVCPVGEDRQHFGRTDPGIYSRQYPDPALARAWAHVRRYGLKGAGKEV
                     "
     gene            17768..17998
                     /gene="hypC"
                     /locus_tag="PK679_03235"
     CDS             17768..17998
                     /gene="hypC"
                     /locus_tag="PK679_03235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0065003 - protein-containing complex
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="HPC55004.1"
                     /translation="MCIAVPAEVIEIREGNIGIVDYGDLQQEVRLDLVDVKVGDFVLV
                     HVGFAIQKISREEGLKTREIFRQVYAAMQESD"
     assembly_gap    18001..18100
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            18467..18646
                     /locus_tag="PK679_03240"
     CDS             18467..18646
                     /locus_tag="PK679_03240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55005.1"
                     /translation="MDKTGVASLIAGIILLVLGAYGVWIFLPDVILFLKGVIGILAIL
                     IGIFLVIFGVILIKD"
     gene            18795..19691
                     /locus_tag="PK679_03245"
     CDS             18795..19691
                     /locus_tag="PK679_03245"
                     /inference="COORDINATES: protein motif:HMM:NF039195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PsbP-related protein"
                     /protein_id="HPC55006.1"
                     /translation="MDRMKVLVVLLVISLSGNVFFLVTGGNNPVSEKISQSLLYAYHQ
                     AFPPLDNETISLAENESNQTYNNTTEAVQSGGDEKEFTARDLLLMIEKNEISDEEILQ
                     MLLSLENETVPAEEQEVNVTPTPDPNAWKVYESSKWHFSIPYPPTWTVKEGTSASSVV
                     TITAPIETKCSSESKQCYQYVASLSVSIDTNPGTGGLEEYFNKKIASLQRQLAITATS
                     KSATTYISGERAYWIEYYTRDSRGNPSKRYMQYFALLDKKVYILTYSGPYSTNENVYS
                     RNKGDVQKMIEGFTVKREYVIV"
     gene            complement(19926..20180)
                     /locus_tag="PK679_03250"
     CDS             complement(19926..20180)
                     /locus_tag="PK679_03250"
                     /inference="COORDINATES: protein motif:HMM:NF012353.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFYB/HAP3 family transcription factor subunit"
                     /protein_id="HPC55007.1"
                     /translation="MPKAVKKAPVKKKAKSTRSSSFDLPIAPVVRIAKNSGAERISMD
                     GTRAIVARTEKYIAEVARKAANAAASEGRKTIKAEDVEKF"
     gene            complement(20391..21041)
                     /locus_tag="PK679_03255"
     CDS             complement(20391..21041)
                     /locus_tag="PK679_03255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="HPC55008.1"
                     /translation="MKEGTFIKKVKKKGLFQMIFPEEYDFEAMLAGQAEKTVECVEAF
                     VRWLKAEPVGDPAELRYMAATVDGMRYEMEEKLMDSFSTPFDRQDIYTLSRQMDYIVN
                     YSYETAREMYAFGVEPDIPIVQMAGELLRGTKCMAAGVTAIGSDTKNIEKRIRSARQA
                     MHTIDDIYIESMARLFQTKDAMGAMKKREVYHHMRDAGRALRATVDTLHHVVVGIS"
     gene            complement(21046..22071)
                     /locus_tag="PK679_03260"
     CDS             complement(21046..22071)
                     /locus_tag="PK679_03260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HPC55009.1"
                     /translation="MYEAVLLTILISLAFCFTNGFQDASTIAATFIASRSATPRQGII
                     FVTLFNVIGALLGGTAVVLTISGFLAGGDGPEMVLVILSGILAATAWNIVTWWWGLPS
                     SSTHGLIGGLIGAGMAHGGPAGINWGITDLLSPSPHMSGVSGVIIFLVVSVLLGLAGG
                     YIMRSLSRLALRNAKRRVNRLVVRLNWCSTALMAFYNGANDSQKQLGIIALVLFYSGL
                     VPVFSVPLWARVLCAALLGAGTLLGGWRIMTTLGRRIFRIEPVHSFDSQVSSGTILAV
                     STLAGAPVSSSHIISASVIGVGAAENPKKVRWRVGREIVTVMVLTIPATIIVAYGAAS
                     LLFSFMR"
     gene            22256..22501
                     /locus_tag="PK679_03265"
     CDS             22256..22501
                     /locus_tag="PK679_03265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55010.1"
                     /translation="MRLRLKDEMEYAIWKITGLSIPYNENVIPCLAQKIALETGEDPG
                     EVSMTLSARIKEIIWEDVSNHYRVRESKNEVLEPAYE"
     gene            22595..23092
                     /locus_tag="PK679_03270"
     CDS             22595..23092
                     /locus_tag="PK679_03270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55011.1"
                     /translation="MEKNSGYAVYLSITALLAGLIFLGGCVQHGITSPGNTTPVPATL
                     TPGVTHPGGNQFLGTWQHFGIIGTNRVAIRFDFLSNGTGRFDLVAPDLDPPFRKTMVF
                     SWESEGDRLWLGSSNEKQHLDIRHDAGTDRLKVTADNESGLFIGEDFVPGPFYWEFTR
                     AEEQS"
     gene            complement(23269..23343)
                     /locus_tag="PK679_03275"
     tRNA            complement(23269..23343)
                     /locus_tag="PK679_03275"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23305..23307),aa:Glu,seq:ctc)
     gene            23531..>24633
                     /locus_tag="PK679_03280"
     CDS             23531..>24633
                     /locus_tag="PK679_03280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HPC55012.1"
                     /translation="MAGLEEQIRELEEELQRTPYNKATSKHIGRLKAKIARLKDEAVS
                     RAMRAGGGSEGYSVRKSGDATVVLVGFPSTGKSTLLNVLTGTKSEVGAYAFTTVSVVP
                     GALEHRGARIQILDIPGLIAGAAMGKGRGKEVIGVVRSADLIVILVDIYNASHVDVLL
                     SELYDAGIRINRPKPDITIRKTASGGVRMNHVGVLDLDIEEIRAILSEHRMVNADVLI
                     RGNATQEDIIDAMLGNRVYIPAFVAVNKVDLVDEATREAIRNDISQRFGSPPILISAH
                     TGYHMEEFKDWIFDTLGFMRVFLKPQSGAADLEEPLIIRSGSTVGDVCRRLHRDFVER
                     FRYARVWGESVKHPGQRVGLSHKLKEGDLLSII"
     assembly_gap    24634..24733
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(24962..25477)
                     /locus_tag="PK679_03285"
     CDS             complement(24962..25477)
                     /locus_tag="PK679_03285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HPC55013.1"
                     /translation="MKVLVVIPPENFRDEELAKPLEAFEKAGITFDIASTRRGQCRGM
                     LGARATASLSLEEVEPSDYAGIVIIGGTGSPVHLWNNDMLVELVKYFSKNNRLIAAIC
                     LSPVVLAHAGILKGKSATCYESPSSTKEMLKGGARLAGTPVVTDGNIITANGPAAAAE
                     FAGAIVRALKG"
     gene            complement(25668..26789)
                     /locus_tag="PK679_03290"
     CDS             complement(25668..26789)
                     /locus_tag="PK679_03290"
                     /EC_number="2.1.1.213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004809 - tRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine(10)-N(2))-dimethyltransferase"
                     /protein_id="HPC55014.1"
                     /translation="MEYVWAEEGRIKFLVPATDPHHPFPPGSAPVFYNPRMELARDAT
                     VLLSKVLPVSRYLDAMGATGVRGLRIAKECEVPVTINDRDPQAADLIRRNSEILGVPV
                     EVVSSDANCLLSGRVFETVDIDPFGSPAPFIDSALKGCGRFLFVTATDTAPLCGAHRN
                     AGIRRYFAIALNNEYHAETGLRILLGFIAREAARYDRGIEPLFSYAREHYCRVHLRLL
                     RGARMADRSLSMMGYVLQCPSCIFRTHTTGILPSHEECPYCRNALVPVGPLWTGPLHD
                     RNLLDRLHESISSSGFRLGGELRKLVDTCRNELDIPHHYDYHGLARYFHISPPPIDDV
                     IHSLRSRGYEASRAHFSGTAVKTIAPHSVLREALTRNRS"
     gene            26850..26924
                     /locus_tag="PK679_03295"
     tRNA            26850..26924
                     /locus_tag="PK679_03295"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26885..26887,aa:Arg,seq:cct)
     gene            26994..27854
                     /locus_tag="PK679_03300"
     CDS             26994..27854
                     /locus_tag="PK679_03300"
                     /EC_number="2.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="geranylgeranylglycerol-phosphate
                     geranylgeranyltransferase"
                     /protein_id="HPC55015.1"
                     /translation="MQEECLILPRSGYIQVIRPVNAVLAGLAGIVGYLMATGTLIPGV
                     IWIFLVVFLVTAGGNAVNDYCDVEIDRINRPDRPIPSGAADRDAVLVCSAILFLCGLA
                     VSFTMNTLCVAIAAFNTILLVWYAISLKRTPGAGNIAISYLTASIFVFGAAFAGAGGA
                     MKVLPIALVTFFAMLARELWKDAEDVLGDAAGGALTLPVRIGVYPVIRLGFVFLVAAI
                     CASLVPFLWWGLPYLAGIAVVDLLVFWTAFRALSCRTPECLKGTRATTLVKYAMFTSL
                     VVFSLAALFL"
     gene            complement(27816..28565)
                     /locus_tag="PK679_03305"
     CDS             complement(27816..28565)
                     /locus_tag="PK679_03305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HPC55016.1"
                     /translation="MVFAPVTIEGIIFLVGEITLLILFGLLVFSLLLVWISIVSINTG
                     RLILPRFVKAGMVLVEGLAKAFFRLFGLEDSEVLTFFITLHNTMHKQSFAEIPPEERA
                     IFFPQCLRSSRCPAHLSPEGLACRSCGSCSIGYWRKVLSAMGYRVFIVPGSSFIKRMV
                     RAYRPRAIIGVGCLAEVKDGLEMSDKMGLVSMGVVTQKDGCVETSVDWEKVMEVASLG
                     VDPARIPHEASEALFSSTPSQEEGREGEHHE"
     gene            complement(28570..29622)
                     /gene="mtnA"
                     /locus_tag="PK679_03310"
     CDS             complement(28570..29622)
                     /gene="mtnA"
                     /locus_tag="PK679_03310"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046523 -
                     S-methyl-5-thioribose-1-phosphate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HPC55017.1"
                     /translation="MKSIETISWEDETGNVILIDQTRLPGSYRLVRCRTTDRLVRAIR
                     TLEVRGAPALGIAGAYGVLLAIKQIRERDHSLFLRRLYREAEKIRSARPTAVNLSLGV
                     RVVMEAVESAGSVKEAKENAHAAAKAFADAESRSCHELGTCGAALIPEKCTVLTHCNA
                     GALACREWGTALGVIRSAVVQKKQVSVIACETRPLLQGARLTAWELRRDGIAVTVIPD
                     SEAAFLMQRHEVDLVIVGADRITRDAVFNKVGTYMHAVCARYHNIPFYVAAPVTTFDP
                     IHAARDVVIEERAREEVASCGRATVVPDGVAVKNYAFDITPHDLVSAFITDIGVFHPP
                     PDWMALEKALISRNPV"
     gene            complement(29619..30902)
                     /locus_tag="PK679_03315"
     CDS             complement(29619..30902)
                     /locus_tag="PK679_03315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase iron-sulfur
                     subunit A family protein"
                     /protein_id="HPC55018.1"
                     /translation="MTEVVVIGGGVSGIQAALDLANHGIDVCLVEKEPSIGGHMAMLD
                     KTFPTNDCSMCILSPKMMDVYRHPRIRTMTCARVVSVSGTPGDFHVTIRMMPRFVDPE
                     KCNGCGDCIEVCPVEVYNRFDAGLGVRKAIYKPHSQAVPDIVVRDTDHCIECGLCYDI
                     CGREAILKEDRERDITVHAQSIILACGYEVFDARKKDQFRYLSLPDVVTGLEFERMMN
                     ASGPTGGKIRRLSTGETPRSVVFIQCVGSRDVPLGRPYCSGVCCMYAIKNAILLREKY
                     PGIDVTILYMDIRAYGKGYEEYYQRAIGAGVHFVRGMPGEVTGQGDSIRIRVENTENG
                     EILNLNPELVVLSTGLEPAPDAEDLAGMLGLPRESTGFFRTLNEKVDTVATERPGIYL
                     AGTVTAPRDIPDCVAHSGAAAMRAFIDASRNSQCR"
     gene            complement(30895..31386)
                     /locus_tag="PK679_03320"
     CDS             complement(30895..31386)
                     /locus_tag="PK679_03320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HPC55019.1"
                     /translation="MAVGKAGTGGRFIAANATVLGDVEMGDSVSVWFGAVVRGDRDRI
                     TIGDMSNVQDNAVIHTSAGFPVRIGREVSIGHGAILHGCTIEDRVLVGMGAIVLNGAV
                     VGRDTLLGAGTVVTEGAVIPPGSVVVGVPGKVIKQVTEEQKDHIVRNASVYWEMAGRY
                     RDD"
     gene            31417..31920
                     /locus_tag="PK679_03325"
     CDS             31417..31920
                     /locus_tag="PK679_03325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine adenylyltransferase"
                     /protein_id="HPC55020.1"
                     /translation="MKVMVGGTFDPFHDGHKRLITRSFELAGRNGTVVIGLTTDAFAS
                     RKVHPVRPFEERRKALEGFIRSEGFLAAYSIEPLNDRYGSALDADFDALVVSEETLPV
                     AREINVLRRERGHRKVDIHQITCVLAEDGKWISSTRIYRGEIDEHGRVIRRESENARD
                     TGRGSHS"
     gene            complement(32319..32924)
                     /locus_tag="PK679_03330"
     CDS             complement(32319..32924)
                     /locus_tag="PK679_03330"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55021.1"
                     /translation="MKKGLALVLTLCILGTGVAHCLAAPPLDAISAYNQGVDLAMEEK
                     FDDALASIDQALSLDQNFTLAWITKAGILNVKGRYNESLEASERALAIDENQADAWTN
                     KASALISLQRFEEGLEAANRAIELDPRLSEAWIDRATALSSLGRTKEADEAMAMVKFL
                     TETPSTTSPTTVPTTPAAPTFPFMALLASGVALFLAREKIR"
     gene            33484..35556
                     /locus_tag="PK679_03335"
     CDS             33484..35556
                     /locus_tag="PK679_03335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative cobaltochelatase"
                     /protein_id="HPC55022.1"
                     /translation="MSPVARRTILPFTAIVGQEKMKKALLLNAVNPRIGGVLIRGEKG
                     TAKSTAVRALAELLPEIEVVRGCPFHCDPHDPREMCEDCAGKFSRGNTLEAEWQRVRV
                     VDLPLGVTEDRLVGTIDIECAIKEGRKVIEPGILAAVNRGILYIDEVNLLDDHIADVL
                     LDSAALGVNVVEREGISFSHPSRFILIGTMNPEEGEIRPQLLDRFGLQVSVEAIEDPE
                     QRMAIVRNAEAFDADPGRVAGEFSAAQEALRATIIRAKEILPQVTVPEDILRALVEAC
                     LSLGVKTHRAEIAVTRAARTIAALDGRTEVTRDDVREAMEYALPHRMRRKPFEEPRLD
                     PDQLDSAMKNADENRRQEENKETSRGEEKGKAPPHPPGQGGEESGQPRQQQPRSSEGE
                     GRERVFGIGDPVDTRQISLTRDRDRERRKRLNGRRIETYSSGRNGATISSRLPEGSGD
                     LALDATVRAAAPYQHARTRGELAIAIREEDIRERVRVGKVSASCVFLVDASGSMGAMK
                     RMEAAKGAILSLLLDSYQHRDRIGMVAFRKDRAEIVLPLSHSVDLAQKSLADLPTGGK
                     TPLSAGLWKAIEVLEREKQKNGEAVPVLVLISDGRANVSSGGDIRAEIRKAAQMLRER
                     SIHTVVIDTEETRSSFVKMHLGYCREVAEVAGGRYYPVSDLSPATIRDISGAEIAGLF
                     SGTRFSAA"
     gene            complement(36381..>37144)
                     /locus_tag="PK679_03340"
     CDS             complement(36381..>37144)
                     /locus_tag="PK679_03340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55023.1"
                     /translation="PLTGTAPLSVQFTDLSTGTITARTWQYRSGNGTWTQFSTESNPA
                     FSFSDPGTYDIRLTVSGPGGDNTKERTGYITVLSQPGPTADFSASPLTGTAPLSVQFT
                     DLSTGPVTLRMWDFQNDGQVDSLAKNPTYVYRKPGVYSVRLRVRGPDGTTEKVREAYI
                     TVTAPEKPPVARFTLSPRSGIVPLTVRFTDLSTGNVTSYLWNFGDGTTSTEANPTHTY
                     TRAGFYRVNLRVSNSAGSASVPSVVFAIPSFRLPW"
     assembly_gap    37145..37244
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<37245..40998)
                     /locus_tag="PK679_03345"
     CDS             complement(<37245..40998)
                     /locus_tag="PK679_03345"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC55024.1"
                     /translation="MNKDLLDSAYYSHLATVIVIFVFLAIFPAVSADGYVGGTPLSTI
                     RSGVVSGGLYVDAEPPAWGPSDVTRTFTQLPEGVDIEWARLYVAVYAGHMKNNYAGTA
                     TIFFDGDGDGTFETEIGNESLDTPGGYTYPGEGGSGTIAVNDHCTRVTSDYLMWYDVS
                     QVISSRTPSARVVTQKVDASFDGRVKMLTLVVAYNDRDTDQVYYWINQGHDVDSYYAD
                     DHGMPYTGVTPFNLSGLSGTVQSATLTVNHLASTDGFYTWCGDPLPADPSASTVPPGW
                     NVQGAYAGYNSWDVTDLIEPGAINDLTYDRVGQFYKLPLAILSVSLAPTPSPDLEITL
                     VNPVTGNVFAREPNTVRVTIRNNGPGSSGQTTVRVLSSDGFEGYSTVPPIAAGQSITV
                     PVVDTTIRNTAGEMVTYTATVDPDNLFIETNEGNNAKTSTTKTVIYNGYKGARYWTGK
                     NDIVTARTFDLHGGILHSSGNSAYKPGGIGGASWNDYTVTWTTGDLALPPGATVKEAR
                     LFVPYTWDNSNEVPDQFRITFNGNVIPYETWYNDKSNFGGYANYVYGLLAYNVTDYFS
                     TGGNTAIVHKDNAGSNLAVYGLTLAVVYEKAGEPRRQIFLNEGFDILGADDTGYATTP
                     EEATAYLPFSGMVLAPGDATHAYLTTFVPAGNGPEGDLLWNGATVATNVWDYGSSSGT
                     QVAVDTRDVKSSLLVDGNEAGIRSTAGSTPLLAASHAFLVVEYQDDAIHADFSANLTA
                     GPAPLVVQFTDNSTGIITSYAWDLDGNGIIDSREQNPVWTYTTPGTYTVNLTVTGPGG
                     TDTMEKQGYISVTGTPLPDLVITGISTNGNELFASEPNAISATVLNNGTGAAGPFSVR
                     FNVSGALYTASLPGLAAGANGTATITDTILRTAGDTVMITAEADPDGDIPEIDRTNNG
                     ADLTRVVANNGYKGKRYTGGSDIGTVATFEGRINLAVSTGDSAYRSTGWTGSATNWTV
                     SDLHIPENATILHARLYQGYTFDQTPGGKPSWTARFNDETITPDVTYTDRKGYGTYNY
                     PSGVFVYNVTPFFSKSGNHLVVTAEEGNSNGLYGSLLLVVYADEREPQRKVLINEECD
                     LLYAGTSRFVSDEEATSYIPFQGASGDGLQEARVIAFLYSANEAGKSAFIFNGNSHGD
                     LSGGFEAGSQVTLKEFNVTGDMAGGDNTALYRSVMVSGSGDNMVAAGAVLVLGYAEEP
                     PAADFSASPLTGTAPLSVQFTDLSTGNITARTWQYRSGNGTWTQFST"
     gene            complement(41232..42416)
                     /locus_tag="PK679_03350"
     CDS             complement(41232..42416)
                     /locus_tag="PK679_03350"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55025.1"
                     /translation="MKKMRSGSRILPLFTIMLIMALFAVPALAGNTLTATGEIVSVPP
                     PVAAFTGSPLSGTAPLMVAFDASSSTGTITSYAWDFNNDGTTDYTSATPTASWTYSAT
                     GTYTVKVTVTGPYGTDEKVKANYITVTAPVKPVAAFTATPTSGYAPLSVQFTDLSTNN
                     PTAWKWEYRKNPGTWVQFSTGQNPSFTFNETGFYSIRLTVTNAAGSNTVTRMNYIIVT
                     RLPKPVANFVASPTSGGSPLTVQFTDTSMNNPVTWKWEYSKGSGTWVQFSTAQNPSFT
                     FNETGSYSIRLTVTNAAGSNTVTRANYITVNPVRKPIALFSQDKVLGRAPLTVSFRDR
                     SLYNPTDYFWTFGDGATSTEQNPVHTYTRSGLFTVQLRVSNTAGSDTARGMVFVVSTQ
                     WW"
     gene            complement(42413..47092)
                     /locus_tag="PK679_03355"
     CDS             complement(42413..47092)
                     /locus_tag="PK679_03355"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC55026.1"
                     /translation="MKRLAKKQKWGPFLALLLLLCLAGVAAADPYVGDIPLETVQSGT
                     VSGGVYVDANNDWWPSDPGVQDVEKTFATIPNVNDIDWARLYVSVYCGHMQNNYQGTA
                     AISFDGDGDGTYETALGTETMNVPYTFPHDGGSGPVKVNDHMNRVTSDYLMWYDVTSL
                     ITSQTPKAHVVTSALDGSFDGRIKVITLVVAYNDGDTDTIYYWVNQGHDTDTYYDTTG
                     YIGSTNFDLSSLSGTVQSATLTVNHMASSDGTYAWGGDPIDSDPATGNFQGSYFGYNI
                     WDVTSATTFGDIYDLTYNLTDQFYKIPLAVLAVKKAPSYVSPVADFSATPLSGTTPLN
                     VQFTDLSTGPPTTWKWEYRLGSGSWTQFSTEQHPFYTFISVGSYRIRLTVTNPVLPGG
                     NTNTSPAGYITVSAPANPDLTITDLRPVTNTPFAKETNTVKITVKNIGGVESPATTVN
                     LISNDGFSGSASVPALASNAETVVSILDTTVRDIAGGSLTYTGTVDPSNTVTESNEGN
                     NVVANTYTVAYNGYKGKRFWAGASDVTTKKTFDLHGNLLYSPGDSTYRSGGVGASAWN
                     DYTVTWTAADLPVPSGATIREARLYVPYTWDNTNEVPDRFSATFNGHLLPDDTLYTDK
                     SNFGGYANHVYGLLAYDVTPYFTTGGNSVVIHKDAETSNLAMYGLTLAVVYEKADEPR
                     RQIFMNEEFDLLGADENNYATTPEEATAYVPFSGLSINPANVASASLITFVPSGNGPE
                     GILLFNGNTLGTNVWDYGSVSGTQVAVDTRDVKSYLSGTNEAGIQSTAGATPAMAAAQ
                     QFLVLTYTEAAPVAGFTGTPTSGDAPLEVQFTDASIGSITSRSWEYRTGGGSWTQFST
                     DVNPSYTFTAAGTYDIRLTVNGPGGSDPEEKQAYITVTEMAPPVAQFTASTTNGLAPL
                     SVTFTDTSTGNPTAWKWEYRNYDGSWTEFSTVQSPTQSFSTPGTYDIRLTVSKGAMSD
                     DETKTHLFAVSGGREPLTTVASGTVSGDLYVGAFQTVPFGNQPASGITFREFDQPFSI
                     PSSAVRNIQWARLFVTTYSGSASNSYGHRQTISFDGNGDAVYETTLGVEDCDIAAEGN
                     GNSYPLNDHVTKVFSDYEAWYDVTGLITATNPAARIRTEQITGKSYDGRLKAVTLVVA
                     YNDGDTDQVKYWVNHGHDWINSGTTQTTFDTSSVTAGFTNATGRNLATSSKDGRYTFN
                     GVAQSWADPVPPVNYFDFNIWDLKATNSIIPGSGSTLVYEPASGQSFKTVLSTVTVRY
                     ATPAPVADFTPASPVTGDKPLTVEFTDASTGSITTWDMDFGDGSPHGSGPGPWSHTYT
                     ARGTYDVSLTVTGPGGSDTKTKTGHIQVMEPAPNVDFTFSPASGVEPLTVNFNATNSG
                     GAVTSWKWEYSADGTTWTQFATTEDASFTFSNGTWSVRVTATGPDYSDTETKLNIISV
                     GESSINVTMSPGSIDFGTMQAGVDETGSSTVSVDVTGGTAWSVTASANNGGYMSTGTV
                     NLANPFQLSKTDGSGYQAMTSSFADFLTGAAGVDGSGTAFVKQAIAASDAPGSYSITL
                     TFTGGFV"
     gene            complement(47252..48208)
                     /locus_tag="PK679_03360"
     CDS             complement(47252..48208)
                     /locus_tag="PK679_03360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55027.1"
                     /translation="MNRNTPTHICLITLALLIAGALLVSPVLALKVEGARIALDVEPG
                     KIYTSPIGISIGENEAGGDYAIEVLGFGQAPADGSYVALEAGRDTSTYSARPFITVDK
                     PVVSLKPGEHAMVVATISVPADAKDGGRYAIILVHPAPSASGAPAAFATAVAIPVFLT
                     VKAGTVRETGEITAVEPPVAEVGKPFAVTTTFRNSGNYHFYGVVHNVTITDAQGRVIA
                     SVKSEPFVRAIVPGQSVTFTAPVANGLPKGNYQVVARVEMQDGKVLAEKKVTLQAGSP
                     PTQATTVAPSKGFLPGFEGVIAIMGIACALFLLIRMGKEGER"
     gene            complement(48303..50483)
                     /locus_tag="PK679_03365"
     CDS             complement(48303..50483)
                     /locus_tag="PK679_03365"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC55028.1"
                     /translation="MKTLTMLGILALFLLLVIPGAVSAADLTVSGSVVDEDLTVTGLT
                     INPGSASGHDVISANEPNTLRAAVKNNGGLAAGAFDVSIVIGAYTQTVSVPGLGAGAT
                     TNVDFTYTPTTTGAISIVITADSGSAIAESDETNNALTTSSNVYYNGYKGKRYTAGND
                     FTTVNTYTGRIGVVYSTGNAAYQSANWMSYSASFTAGPSSADLIIPSSATIVSARLYQ
                     STNWDQTTGASALWTATFNSATVTPTATYTDRKGYGGYNYPSELVMYDVTSTFNKAGT
                     NTWSLSSGSNLNVALYPTYMVVVFEDPATQTEKTIYINDECDLLYSRANYNTNDAEAT
                     AYALFNGVDITGMASAKAIAFVAAVNEDGQSQFIFNDADYDDFYIDATKSTTQTVSIK
                     EFTLTNLVSGANTAKLQSRDATDGDLMQAQNLILVVEKTEGAVDITDFSASPTSGDAP
                     LDVTFAATTTGNVVGYAWDFDNDGDTDSTAASPTYTYSTPGVYSVKLTITGISSSDTM
                     TKTDMVTVKTPAPDVDFTFSPASGVEPLTVAFDATNTGGAVTSWKWEYSADGTTWTQF
                     ATTEDASFTFSNGTWSVRVTATGPDYSDTETKLNIISVGESSINVTMSPGSIDFGTMQ
                     AGVDETGSSTVSVDVTGGTAWSVSASASNGGYMGTGTVNLANPFQLSKDGTNFQAMTS
                     PFADFLTGAAGADGSGTAFVKQAIAASDAPGSYSITLTFTGSMA"
     gene            50900..52690
                     /locus_tag="PK679_03370"
     CDS             50900..52690
                     /locus_tag="PK679_03370"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC55029.1"
                     /translation="MHTARSAITACIVLSLIVFATPCTALYDFEGLAFRPAAMGEVDG
                     RLVTAGTFGLVNPPMECTITLDRAPVWARMYCGVWGGTERYTGWVRFTVNGRPMEQIT
                     LYGQDDRTEGIYCSGHGVYWIARDATSLLSPGQNTISVSTSKGESGSRIDGRVYAVMV
                     VAAVEDTTGIATRYIIMEGNENLHGEGWSGTNPTRKDRVEVPIGGMPTGSVKKADLSV
                     FLAATNRGQPDYVLFNGADMGVVPAKGTYLPGAKDIGNEQSFDAAGGEGIESRYVDME
                     SFDVTGHLRAENLLVFERGRDLDGDGNITTTGATPEGEDYVHPCLVILAAEREGQASS
                     PALSVEPFEINNAYAGERAEVKAVVWNTGRALKVPVTVSLLVDGTRVGSTEVTLSPAG
                     RADVSLPWDAAGGTHLVSVEATAPGATPGKAEKSMKVGTPVDLVVSVGPPERQDGPGS
                     SPMATTPFPIAALAGGSAIGLWLCSRRSGLLPLIVTVAAVSSLLVIPFVHASPAAGTS
                     FTAYSLPVEIRNTGGSDAPAFPVTVILDGEKVTRISVPGVPAGGFVRQDIAVYTTPGR
                     HTVSVIADEEGTVAERNRTNNRADATYDFP"
     gene            52677..53663
                     /locus_tag="PK679_03375"
     CDS             52677..53663
                     /locus_tag="PK679_03375"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC55030.1"
                     /translation="MTSRNAYLLFAAGTCILFCTAAAGASYAGDRPLALAYRGTVSGG
                     YTFSEGDGGYSGTLNPGQTYTASFTREIPGGAVTRFERLYVYWTWSRIDQSASYPNME
                     VRLGGPEGPLLVLSARYTDSKGFASKNDFFSGLDSYLVPATGGENFSVYISNTAKDGS
                     TFAIQGTSVLSVYEVTAGRETAIWVAEGADLLYRSYGIPPELATTRVDFPGRVDIPRV
                     ESARLFLVAPSAGFSREEVPEMNQVMMNTPGRGQLPPLVEPVLKVLFPHYRGRAWSDA
                     FSADEDHQIGIAQAEVKPFLRYSDNFIEVRDNGDYLMLCNAVLSVTYQEKRE"
     gene            53660..54328
                     /locus_tag="PK679_03380"
     CDS             53660..54328
                     /locus_tag="PK679_03380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55031.1"
                     /translation="MSPPMVETRQLTRSYPGGVEALRGVDITVGTGEFVAIVGRSGSG
                     KSTLLNILGGIDAPTGGFVSIRGKMLDYTNRKALIAHRRTTVGFVFQQFNLIPSLTAR
                     ENVEYPLLFSYRPASERRKKAEVLLATVGLAGRASHYPGQLSGGEQQRVAIARALVSD
                     APLILADEPTGNLDSATSGEIFSLLRSLNKEKGVTLIVVTHERELADYADRTIGMKDG
                     RVVA"
     gene            54325..55545
                     /locus_tag="PK679_03385"
     CDS             54325..55545
                     /locus_tag="PK679_03385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55032.1"
                     /translation="MTIRLLEFIELAFRQLFRRKVRVILTVAGIAIGVAALVGTVSLG
                     EGIRTQAVEAIRTQSDLTLIEALPAVEGNTLQLVTATKASAAGSLPGIKASAPLVRST
                     FATRGQTYVQVVGLPAGSLDDVLISRFQKGRGFTAGSNEVVLGASLGQKLQRYEGARI
                     GDPLVLIRRTYDTAGRPVDNETRVVPVGIMEERGDDFDQILLMDLSFALSLGADEGGY
                     SGVLLRTTGPDQVFPVAGGIRALGLSPRGSFEQIEAVNRMMDMVVIFLGIFAGLSLLV
                     GGLMIASTMITSVYERTREIGIAMAVGASEGDVMEMILTECAVLGCIGGICGDLLGIL
                     FAFILNTLGGPFLASRFGDAFAGLLDSEIALVTWPLLAGGLALAIGLSLVAGLYPAWK
                     ASRLNPVEAIRSGR"
     gene            55550..59104
                     /locus_tag="PK679_03390"
     CDS             55550..59104
                     /locus_tag="PK679_03390"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC55033.1"
                     /translation="MERKELFRALVLVLWIVTVVSIPTGADPYLGGIPLETVREGTVS
                     GGIFVDAAYPMSTDGSATFVLPAHTGIQWARLYVVVYCGHMQNNYQTRADIEFNGGQG
                     ITKLATEILNVPYSFPGEGGSGPVRLSDHGNRVTSDYLMWYDVKDRIQGSNVLVRVKT
                     SRPQGYTGTFDGRIKAIVLVAAYEDGDQDKVFYWVNQGHDEDSELTEEMLGETYVGET
                     TFGTGMLTEDWDKAELNVVYLASRNAEYDFNGDPLPAGKPQGPYAGLDRYDVTDSIRK
                     KRDSDLSYDNIERYFKIILATLAVRFPGSETGNLSVTSSPPGAKVSIDNEEQVQRTNA
                     TFSGIPAGNHVVMVEIPGFRVPAPQTVLVQTGETTSIHFILYQGKGNITVETNPPGAE
                     VFIDGVKHPALTPCIIGDIPAGEREVVIRLTGYREWREIARLSDGETLSLQAGLFPAG
                     DGGFSTGEVPPATVQAPSGYRGSGLTLYKQGTLRGTLFSACAGDYTGMIPAGQERTFI
                     LPNSLPGEGEIVLSRLYLYTTWSHDTTKREGVPAVPTVFWNGQELRLDAIYADRKGDG
                     IYDYPVQTFAYDGKGVIKTGEKGTVTVRNSGETGREFATYGVLLVALVENPEDPEISY
                     WICEGSDIVFPDPRFGTSAQEARTRVTFPGDIEISGIDSARLFIVSTAASGEGKDQNI
                     VIFNGGEWYNLLNAGSSGISMADLDVRSYLLKGDNILEIASFSAEGGGDYMENRNAVL
                     VLTHADGGERQTNQGEGTDKGEVRPGTGETSLPPGGLATGTSPTGWEPRSFLDSAIEW
                     IFAHIFKVLGLSPLPAGEDYPIPHPASKTPAFDDLQRPVPQEQEEETGKAKSGETMFL
                     SGNPTGDAETLPTPVMTESTLMPTGTNDTLSPEKPVTGGIFVTSYPGGAAVFIDGRKV
                     LSKTPLVANWLKAGLHTVRVDQEEAEFTPDSRQVWVEPGEITPVSFTTGGAYFRTLTI
                     ESREFEAASFTVNGRGPVLVLPAKVTLEGHSPYVSVMVDGELYSQTIPPRIQDGSSFI
                     FTREGGAAASVKVTSTPPRAIISIDGFPTKKVTPATIGNLSPGQHRIVVSCPGYFPAE
                     RLVTLVDFASEPIDMSVDLSLEPYQWGNLTVESDPPGARIYLFGKDTGRKTPATFNYL
                     QIGSIQGKIRWDDSEKDFEAEVLPERDVGILVRQTRRE"
     gene            complement(59234..59530)
                     /locus_tag="PK679_03395"
     CDS             complement(59234..59530)
                     /locus_tag="PK679_03395"
                     /inference="COORDINATES: protein motif:HMM:NF013877.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55034.1"
                     /translation="MGFFGVDDLPAGSYCDPFSWDIASPFDRIKDGIDILIIGCQPQR
                     VSYPVVEYGLSDPVRNAIPRAVGIVHAVIGTGAGLSERDLICELKGELRQALSR"
BASE COUNT        12943 a        16168 c        17006 g        13230 t
ORIGIN      
        1 cggggtgtac gatgttaaaa gcaacgattg atgcagatat tctcaaagag tccatcgacg
       61 ccatatcagc ccttgtcacg gaatgccggc tccataccga tgagaacggg atctctacca
      121 gggccgtcga caccgccaac gtggccatgg tctccctttc cctgaagaag gaagcttttt
      181 catcattcga atccacgaag agcgaactgg gcctcgacat cgccaaatta aagaatatat
      241 ttggaatgat ggggaaaaac gagccaatca gcctcgagct tcccgacaat gggcagaaac
      301 tgcgggtcag ctttgaagga taccgctatt ctatcaccct gcttgacccc aataccatca
      361 ggaaggatcc caatcccccc aacatcgacc tgccgggcaa ggtggtactc tccggagccg
      421 acctctacaa ctccataaaa gccgcagcgg tcgtatcaga caagatagct cttggcatcg
      481 atcctgccca gcagatattc tacatggcgg ccgagggaga caccgatcac atccggaagg
      541 agtttggaaa gaacgaggtc acgtttttga acaacgtgga agcccgctcg ctcttctccc
      601 tcgattacct aaaagacatg ggcaaggtca tgagccgtgc ggaagaggtg gagatatcta
      661 tcggcatcga tcaccccgtg aaatttgcat tctacatagc cggcgggaag gggtacgtcg
      721 aatacctgct cgcaccccgt atcgaggctg attgatgcgt gtctccctgg agacaagaga
      781 ctttgcaaaa tacccttttt tgaaagaatc gcagcagtac atgctgcggg aaaacgaatc
      841 gctcgagaag ttcctgcaga ggagtgcggg gaaggttgcc ctctcccacg cggtggaaag
      901 ggtcaggcag gccgtcgctt ttacaggccc gacactcccg tcgtcttcgg ttccggaact
      961 cccgtcggac cagctgggtg tccgcctgga gatcacgtcc tttgtccttg cacgcgttct
     1021 cgtctcgtgt gcccgtgaca gggcactcat ggaaaggctc gcccgttacg aggcgcaaag
     1081 ggcgcacgcg ttcctccagg cagaggaaga agagaagagg atatttctcg cgggaaagat
     1141 cgggttcccg ctggagggtc ttttcctgcc ggtcccccgc tacatcgagc tgacggcagg
     1201 catgcacgag gagcgctgga ggctcgtcaa cagggaggtt tccgggggaa atgtattgat
     1261 cgatccactc gagtccgagg aactcctcag ggaacagata agaaaaactc tcctctcatc
     1321 cctgcccctc gatgtgcccg aatccctctg cacgcttctt gaaccctgcg ttgcaggagt
     1381 ccgggaggaa ttccagaaga aaattctccg ggactttgga gatgtcgagg aatctgcctt
     1441 tcctccctgc atgcaggcaa tcctgtccgc cctctcgggg ggaacgaata tcacccatgc
     1501 cggccggttc gcactcacgg cattcctcca caacatcggg atggatacag cagagatcat
     1561 ccaggtatac tgccgggccc cggactttga catatccaag acccagtacc aggtcgagca
     1621 catttccggc aggggaggga agggaacgga atacacggca ccttcctgtt cagcgatgcg
     1681 cacactgggc ctctgcgtca agccggacgc cctctgcggg aaggttgctc accccctgtc
     1741 gtattacagg aagaagaaga ggttgacaaa aggggaaaaa cccggaggag ggctaggcga
     1801 tagccctgtt gatggcaatc cccgcaccgc tcatcgcgaa gacaaagatg ataattgaga
     1861 ggagatatgc actaccgggt gccatgaagg cggggagtgt caggacaagc gcaaggagga
     1921 ggaaaaagca taccagcgcg cagacaatgt caagcagtcg ggcatccata tagatgtact
     1981 gttatgacct tggttcatat cactgttcct gccctggagg cttttttccg tccggggccc
     2041 cgatgagggg ggcctctcca acagaccact gtaaacatat ggggcacttc cttttttgat
     2101 atcccttcgc cgggaaggaa tggaaacgac ggaaaagagg gatggtgatc atcccgggtg
     2161 gcaaatggtt tttccgcacg aaggttacag ggatatgatc aggatggccg agccggagag
     2221 ggaagaaatc ctgcgtacgc ttgaagaagc cgtgcgcagg ctggtcgaga ggatggaccc
     2281 cgtgctcatc ccggaagtgg ggtcgaacat tgcctatgcc atggcccgcg cgaggtcacc
     2341 ggcagacgtg gcagcagtcg aggggaggat tgtaagggta aaggggcgtg cccatgccgt
     2401 cggcccggtt gcattcggtg caagtgacca cgttgcgcga atcgtcctca cagccatgaa
     2461 gtttgacccg gacgtcaggt gtgccgcaaa catcaggtat acccccgggc tggttgaagc
     2521 atgcgaggag atgctccttt ctgtctgcag ttttgaccgg gaatcccaac cccccggtgt
     2581 gaagacaatg gactggggtg ttgcctcctg ttgcagggac ggagtcccgg atgtcattta
     2641 cgaccggggt gcagtcggca aggaggccat gatacggatt ctcggcgaag aacccggggt
     2701 cgtcgtaaat aacattctta aactctccgc gcgaatagat aaagactaaa agagggatgc
     2761 atgcatggga atcaagccca cctacatcaa ggcaatcggg atggagcttc tcactcacca
     2821 tgggaagcgg ttttcaggga atttcgacga gaataaacag actgtgaccg aagtgaccaa
     2881 tatcgagagc aaaagggtca ggaaccgggt cgcaggctac atcaccagaa aggtaaatac
     2941 ccagagacgg tgaatacctc tctcgtatgt tcgagggagt cattccggca atcatcactc
     3001 cttttctgcg caattcgacc cttgacctcg accttgatgg tctccgctcc aatatcgagt
     3061 ttctcctcga gaatggtgtg cacggtatcg tcccgtgcgg gtctacggga gaatcggcaa
     3121 cgcttacatt cgaagaacat gaaaaggtca tcgaggttgc aatagacgtg gcagggggca
     3181 aggtccccgt catcgccggt accgggtcca acaataccgc cgaagctgtc aggctcacca
     3241 aagctgcaaa ggatatgggt gctgacgggg tcctcgtcat cagcccgtac tacaacaagc
     3301 cgaacaggtc cggccttgtc aagcactaca cggcacttgc cgacctggat atccccgtca
     3361 taatgtacaa tgtccccggg agaacaggcc agaaccttcc gcccgacctt gtggcggagc
     3421 ttgcccgcca cccggacatc gttggcatca aggaggcaag cggtgatatc gggcagatct
     3481 cccggatcat cgaggcgacg ctggacgaag atttcgtcgt catttccggg gatgacaaca
     3541 ttacgctccc catcctcgcg ctcggaggtg cgggagtcat ctcggttgcc gcgaacgtcg
     3601 aacctgcacg catggtagcc atgttcgagg cattctgcga gggagacctc gaggaagccc
     3661 tcgacatgca ctatgccctg tcacccctgt tccgcgccat gttcatcgat acgaacccga
     3721 ttcctgtcaa gaaagccgtg gaactgcgcg ggatggctgg cggcccgccg cgtctccccc
     3781 tcgatgaact cgatgcagaa aagacgaaaa aactcgcgga ggtcctttca acgtatgatt
     3841 aaagttgtca tatgtggtgc catgggaagg atggggtcca ccgtcggacg gctcgttgat
     3901 gccgcacctg accttgccct tgtcgggggt gtcgacctga aacgggggga ggtattcggg
     3961 gtgcctgttg ttcccgcgga ggacatggcc cgcctcctcg aagaaaaaaa gcccgatgtc
     4021 gtcatcgatt ttacggttgc ccctgcagca gtcaaaaacg taactaccgc agcagcgcat
     4081 ggtgttgctc ttgttgtcgg gacaacgggt ttttccgccg accagaaggc agagatggcc
     4141 cgggcaatcg agggacacgt gcccgcagtg atatccagca acttcagcat cggggtcaat
     4201 atcttctggc agctggtcag ggaggcagca cgtctcctcc ctgactacga tatcgaggtg
     4261 ctcgaggcac accaccggta caagaaggat gcacccagcg ggacggcaaa gacaatcatc
     4321 cagattctcg aggaggaggt gggacaacgc cccaaactct atggtcgcga agggatgatg
     4381 gagaggggaa aggagatcgg cgtccacgtc atcaggggcg gggacattgt cggtgaccat
     4441 gcagtcctct ttgccggaaa tttcgagact atacaggtct cccaccgggc atatgacagg
     4501 tcagttttcg cccagggggc agtgaaggca acccggtggg tcgtgggaaa gaaacccggg
     4561 atctacagca tgaccgatgt tctctcgctc tccgcccccc ggtcaaaatg actaaatggt
     4621 aacctatatt tttcatatta tccaaagtta aggctggata gtgcaaccat gactgccgtt
     4681 gttgacaagg acaaatgtac cggttgtgaa acgtgcgttg atgaatgccc cgctgccgcg
     4741 ataagcatga atgacggtaa agcgaaggtc gacaaggacc tctgcgtgga ctgcggatcc
     4801 tgcgtggatg tctgcccgtc cgaggccatt cacctggaat aaaaaatcaa actctttaat
     4861 aactccaatg ctctagctat ttttcaccta tgatacgcgt tggagtgctc ggtgcgacag
     4921 gagcagtagg gcagcgtttc gtccagctcc tggcacagca cccctggttt gaacttgccg
     4981 cgctgacggc gtcagacagg agtgcaggga agcggtatgg agaagtcgtg aactggaggc
     5041 tcgatgtccc ttttccgaag gaggttgctg acatccccat ccgcactacc gagacaaaga
     5101 gcctctccga cgttgatctc gtcttctcgg cccttcctgc agacgttgcc ggaccggttg
     5161 agaacgcgtg tgcagacgcg ggtattgcgg tatgcagcaa tgcgagttcg caccggatgg
     5221 atccgctcgt cccgctcgtg attcctgaag tgaaccctga ccatctcgcg ctgatcgatg
     5281 cgcagcggga tgcggggaga gacggcttca tcgtgacgaa ccccaactgc tcgacgattg
     5341 tcatgtgcct gtccctcgcc cccctccgca aattcacgtg gaccgatatc agggttgcca
     5401 cgatgcaggc aatttccggg gcagggttcc agggagttcc tgcaatgggg atctacgata
     5461 acatcatccc gtacatcggg tccgaagagg agaagatgga gactgaatcc ctcaagatca
     5521 tggggtcgct cgatggaaag actgtccggc ctgcgccctt cagggtgagt gcgagctgtc
     5581 accgtgtacc ggtcctggac gggcatacca tggcgatctg gatcgacatc agggaacccg
     5641 tcgaagaggt caggaaagca tttacggact tttccccgcc ggtcagcgga ctcccgaccc
     5701 tgccggaaaa atccgtggtt ctcctcgatg aacaggaccg gccccagccc agactcgacc
     5761 gtaaccgcgg gaacggcatg acggtgtctg tcggaagagt caggaagggt atccggtacg
     5821 tgaccatggg gcataacacc atccgtggag cagccggagc atcggtactg aatgccgaac
     5881 tgatacacaa gaaaaagtat ctctgatcag ggggccatcc ggatgataaa agacaacaca
     5941 gtattcgtgg ggaacaagcc ggtgatgaac tacgtcctgg cagtggtgac ccagtttaac
     6001 aacggtgccc aggaagtctc gatcaaggcc cgtggcaagg caatctcgag ggcggtggat
     6061 accgcagaga ttgcactgaa caggttcctc gaaggtgtga acaagaagca gatcattacc
     6121 tcgaccgagg tgatcgatac cgacagcggt aaaacgaacg tctccagtat cgagataatc
     6181 cttgctgcta cgggatgaac gaaccgccgg ttttttgcct cccggcagga taaggagtaa
     6241 tcccctgaat tcaacctctt ttacagctca aagcaatcgt tctttatgcc agtgggtatt
     6301 ccgccgatcg accgggagca ttttggcaag tcttcacctg caaagataat tcataaggcg
     6361 gggtaatttt taattttcgc gtattttttc tcaattaccc tttaaaacgg ttcttttcag
     6421 atcaggcgga accagaaaag atattacagg aggatctcca tatatactga acaagacatg
     6481 agaggggtga ctgtcgcagt tacggtagtg tgtctccttt ttttcatcat tcccgtaatt
     6541 gcagtaaccg aggacaagta cgggtatatt accgtcaagg atatgaacat caccctcgag
     6601 cagggcaggg cgtacattga tatccactac acccttgacg aaccaacgag gttaatcgtc
     6661 ctgctgctgg gcaaacagga tctgaaaaac cgtcttttac gcattctcaa ttacgaagat
     6721 gcagaattcg tgcacatcgg gatggataag gccagtctca ttgtcaagga cgtgtcctac
     6781 aactatggaa ggggggtata ctggttcccg gcgcacaggt tcaacatcat gataccctcc
     6841 cttcgggtag tcacccccca gacatcgcgc atttttcagg cgaccaggga gatacccaat
     6901 ggaatagggt atttcgacaa tcccggctga cagggttttc tcatgcgtga ttccttccca
     6961 aaaaggaata ccgcaaatca ctcactctca tcgggcaggt acagtggaca aaaggatata
     7021 tggtttttct cccggaattc ctttcctgtt caggtcgttc cggccttttt cactccggaa
     7081 aggtaccggg agagataata ctgtacccct atgcccagca gggcacaggt cagtccgccc
     7141 agcgtcccgt agaaaatgta ctcgattgcg gtgccgggat cataggggaa atccgggatg
     7201 ttgttcatcg agatggcgta gatgcatgct ccgtaggcaa tcagcccgac agcaccgatg
     7261 aagaacggga aaacgataac ctttgcgagg ctgtccctgt cgtaaaaaaa gttgtcaatg
     7321 atgatgccta ttgacgagac gatacccgcg agtgcaaacc agaggactgc accatacatg
     7381 aatatgagaa gatagagaag aagcccaatc tctgcatagt acacgaggag actcatcagt
     7441 cccatgatga taccaacgat gatcagcagt atccccgcga tataggtgct gaaagagacc
     7501 tttccccgcg taagggatgt ccgtagtgca gtcataaaac ctgtgaacat ctcgtcgatg
     7561 ccaagaccac ggtagaggag gtagattcca atcgccccca ccaccgtgat tgtcgcaatc
     7621 tgcggcctgt ccatgaggta cgcgattgcc cacaggagca ttgcgagtcc gacggggacg
     7681 aggacaaggc gggcaacttt cggatcgttc aggagttttt tgatgatata gtaggtacct
     7741 tcgaggttgg gtatctggct gacaatgact ctcctgacgc tggagacggg aagcctggac
     7801 tggacgatgg ggaggacgaa ctcgtcctct gcaccgtccg tcacaacgat acagttcgac
     7861 acccctgtcc ttgcaacgac ctcactcagg gacgccgcga tcttccggtc accttcgatc
     7921 atgtgcatgt ggttgccggc aatgatcgca acctcgacgt cttctccccg gtttttgagt
     7981 tcgtcgtaca gtgataccgc ctggaatatt gcattgatat cggaatcctc gggatccgcg
     8041 agccccagcg cattcgcagc atggaggcat gcgtcacgtc cgactacggg actttcaata
     8101 tttgccttaa aaccgatgtc atcatcgcga tcaacggaaa ggatgagtgt ccgcccttcc
     8161 tgcatcaata tagaaagcgc aatatatcta taaataattg cctttttccg ggaaaaaagt
     8221 atcagatgag ttttgaacgc tggagcagaa ggatgtcgtc ggtcgtgagc ttttcacccg
     8281 cacggaacat cttgaacagg tgctcggcct ctttcctgac ggctttctgc tcctttgtca
     8341 cctttgcctt cttggtcttc ttgcgcaacc cggagataac cttgtcgtag tcccgcagtt
     8401 ctttctggca ggcgatgaaa aatttgtgtt cggcgtctgc tgcttcctgc gcctcgacaa
     8461 aattcttgtg ggctgcatcg gcctcttccc ttgatttgtc ggctttccgg tagaactcga
     8521 ccatcaggtc gtggtgtttc tgcgcaagtt cagccatctc tgtgaccttt gcgtgaagtt
     8581 cagaggcctg cttgcgaagt tcccgtgccc gtgcaatctt ggttttgatc tccttgttct
     8641 gctcgagctc ggcctcctgt tcccgcattg cctccttcat ctgcttgatc ttctcgatca
     8701 gttccctctc cttgtctgtc gagaaaacct ctgtctgctg cctgaattcg aggtgttcta
     8761 tctgtttctg gagttccttg aggcccctgt tcttgatccc gccatgctcc ttcttgaagg
     8821 cctcgatctc ctcgaagagt gcattggcct cttcatttat cctgttcctc tcgtccttga
     8881 gggactggac ttcgttattg tatttatcac gcagttcctt gttcttctgg gcttcttcga
     8941 cgtattccct ggtctggtta ttcagggtat tgcgttccct cgcccacttg ctggccagtg
     9001 cattgagctc gttgcgcctg ttcttgtgct gttcagactc ggcaagtatc ttctttcgtt
     9061 tctcgatcag ttcgttcagc ataccaatcc atcctcgact gtgcagtcgg aatgcattcg
     9121 cccatgatcc ggttgatgaa caggacgagc ggacagttca atgtgatacg gatggggaga
     9181 ccttgcccaa gtccggagca tctgggtggg ataagcacgt atcccggagt caccgactcc
     9241 atagaaaaaa gtgcagggcc aaaaggcact gcccttgttc acacagctca tcatcatgtt
     9301 caactcccga ttccagaagg gtacctgaaa agaaccttct ttcctgccct tctcctggtc
     9361 atcccggata tggatgattt tctattattt acatgatatg aatgctatta atggtttcgg
     9421 gaggagggaa aagacagcag aaaggcccaa attgcgtatc aggatggaga aaatatggga
     9481 gggtgtttcc cgggtggccc gggtcacccc attatatctg tgcagttgtg tgaatcaagg
     9541 tggtatgtgc ttcttcttcg gcttccttat cctacccact cgagtaatgt acctcctgcc
     9601 gtctggtcac gtgccttcct gttcctgggg agctggggtg ccttgggatt ccccttcttc
     9661 tgttcgaggt cttcgagaat cgtcttgtag gagaccctgc tccccatgat ctttcctgtc
     9721 tggacaccgg tcatgatggc cagtaccctg accttgcctt ccatctcgtt cttgacccgg
     9781 gccccccaga tgacatctgc atgggggtcg agttcatagg tgagagatgt ggcgatttcc
     9841 tctgcgtcct gcagtgtcag gtcgccgcca cccgtaatgt ggatcaggct tccggtggca
     9901 ccgcgatagt cgatgtcgag catggggttg ctcaggcact cgcggacaac gctttcgctc
     9961 ttgttctgct gcttgctttc cccgaccagc atcaccgcga cacctccctt actcatgatt
    10021 gccctgacat cggcgtagtc aatgttaatc agcgatggct gagtgatcgt ctcgctgatt
    10081 cctttcaccg tttcaccgat gagctggtcc atcactgaga acgcctggcc gagcgggagg
    10141 ttgggcacaa aatttttgag cctgttgttg tcgaggacga tcaccgagtc agcggcagat
    10201 gcaagggctt cgagcccctc ctctgcgcgg atgaggcgtg ccttttcgac ctggaaagga
    10261 taactgacca ttcccacaac gatggcgccc tgttcctttg caatctgggc gacaacgggt
    10321 gctgaacctg tcccggtccc gccacccatt ccagcggtga tgaaacagag atcggcattc
    10381 tcgaggagtg cctcgagcgt ggggcgggcc atctcggcgg ctctcttacc cacgtcgggg
    10441 tatccccccg cgccgagccc cttggtcagt gacttgccga tcaggactct cttgtcagcc
    10501 tggatcatgt ccaggtgctg cttgtcggtg ttgatggcaa tggtctcggc gcctgaaaca
    10561 cccatgtggt gcagcctgtt gatggtgttg ttccctgcgc caccgcagcc aatgatcacg
    10621 atacggggtt gccctataaa atcgtcatcc gctgaatttg aggtttttgt catttccttt
    10681 tcaatttcag cgtttttcag ggcttcgttg atgatactct gcattgttga ccctccttaa
    10741 accttgaatg aaacctggtc actctcctgc aatacccgcc cgccccgctg ttcgatcagc
    10801 tggcgaaccg cagcccggac tgcttcagag acagtgggaa actcccctat cgccaccatc
    10861 tgctcaagca tctctatctg ctggtctggc aatctgaggg tgatccgatt cattcacttc
    10921 atctaatatg acatttgtct gacatttgtc agacatttgt ctgtcattta gcgttcttat
    10981 gtctgactat gcagatgaat cctacttata ctaaaaagta tataaacttt ttcatctcta
    11041 tccgacctga atagcactgc tgccatttcc tttatctttt ttctgcacca acgagtttgt
    11101 agaatccttt gggtttttca atgaaagggc aggacgttga aaaggttatt cacgggggta
    11161 cggtcatcag ggccaggaaa gagacaggcg cacgtatcat cgatttttct gcgagcatca
    11221 atccttatcc accggaacta tccctttcca tatcgcgcga agacctttca gactatcccg
    11281 atgataccta taccgagctg aaggaaacaa ttgctacccg ttttggggta tcccccgacg
    11341 agatcactct ggggaacgga tctatcgaaa tcttaaggac attctgccat tgtgtgctcc
    11401 tgcccggtga cagggtcggg gtcccatctc ccacgtttgg agaatacgag tactcttccc
    11461 gtcttgccgg agcaattccc ggtgatggcg cacgtgcaaa ggtctcgttt ctctgcaatc
    11521 ccaataatcc gacaggacat ctccggacga gggacgatat tctcgcgttt ctcgagaaat
    11581 gtgccgcgtc tggctgcctc ctcttcctcg atgaggcatt tatcgagatc tcggatgacc
    11641 ctgcccagag tcttgccggg accatccatc cgaatctctt tgttctccgc tcactgacca
    11701 agagcttcgc agtcccgggt atcaggttcg ggtatggaat cgggcaccct gacctcattt
    11761 cccgcctcga ggcgtttcgc cctccatgga acgtgagcac tgttgcagtg aaggttgcgc
    11821 tcgaagcctt tgcacgttac gatgagctcg ccacatcggg aaagaagatc agggaggaaa
    11881 gagcatggct ctgttccgcc ctccgggatc ttcccatcaa aatcgaaccg tcggaagcga
    11941 actttcttct catccacacc ggacgcgacg tgagggatct ctgcacccgc cttctccgga
    12001 aagggattct tgtcagggac tgccattctt tcgggttacc tgaatcaatc cgggtcgcag
    12061 tccggacccg ggaggagaac gccctccttg tggaggcact agaagcatgt atgcactgat
    12121 ccttgcggga gggatgggaa gccggctggg ccttggcgag aaggccctcg tgactgtcag
    12181 ggaagtgccc atgatacgcc gggttgctga tgcgttcgtg caggccgggt gcgatgttgt
    12241 ggctgttctt tcgccccgga ctccttatac gcggaactgg tgcagggcaa acggaatttt
    12301 ccactacgtg gcggaaggga ggggctacat ggaggatatc atcgaggcgg tcactgcact
    12361 tgagatatcg tcaccggttt tcacctgcgg aacagacctg cccctccttt cttctgatat
    12421 tgtgaaagac ctcatggaca ggtataccac gtgcggaatg gacgcccttt ccacgtgggt
    12481 ccccatggcg cttgcggaag aacatggcta ccagcccccc tgcatcggga tggtatctgg
    12541 catagaagcg tgccccgcgg gaatcaacat cctgcgtgga gacatgatcg catctcccca
    12601 ggaagaggag cgcgtgcttg tagcggatgc ccgccttgca tgccatgtca ataccaaaag
    12661 tgcactcgaa atcgccgaaa ggctcatctc ccaatctcgc cggccctcct gattccctga
    12721 ttcactcttc ccccgtcgca ccctttcccc cggtttttcc gatatttttc gtcaatttca
    12781 cgggaaaatc ataaaatgat tcctgaccaa gtacacatat atgcaggtat cgcgggaagt
    12841 ggaactcgag gggcatatca tcgattcagg gatcatgacc cgtgtttttg acaccatcat
    12901 ggatatgggg ggtaacttcg agatcatcgt ttttgatgtc ggaaagaaga agaccgatcc
    12961 cagctatgcc cacctgaagg tgaacgccga taccgaggag aacctgaatg ccatcctctc
    13021 agagatccac aggtacggag cccgcctgct cgagattcga gacgttgtca cggtccctgc
    13081 agaaggagac cgcgtcgtcc ccaaggggtt ttattcaacg acccaccacc cgactttcgt
    13141 aaagtatgcg ggggaatgga tacccgtccg gcatatcgag atggactgcc tgatcgtaat
    13201 cgacccggaa aaaaagaccg cactgtgcac ccccatctcg aagctgaaaa aaggagatct
    13261 cgtcgtcgtc ggggaagagg gagtcagggt aagtcctccc gagagacccc gcaacgtctc
    13321 caccttcgag ttcatgcacg gaacggtctc gcccgaaagg ccgagtgaga cgatcatcgc
    13381 gcggatagcc cgggagatta tcgaggtcaa gaggcgtgga ggaaaaattg cccttgtcgg
    13441 aggccctgca atcatccata cgggtgctgc aggggcgctc gcacgcatca tccggaacgg
    13501 gtatatcgat gtcctctttg cgggaaatgc cctcgcgaca catgatatcg agtataacct
    13561 tttcgggaca tcccttggaa tggatctctc caccggaaaa cccgtcacag ggggtcacaa
    13621 gaaccacctc tatgcaatat cggaagtgat tcgggcgggc tccatcgcag cggctgtcga
    13681 gaaaggcatc atcacggggg gcattatgta cgaatgtgta cgtcggggta tcccgtttgt
    13741 ccttgcaggt tccattcgtg acgacggccc cctgcccgac gttatcacgg atgcaatggc
    13801 tgcacaggac cgcatgaggg agcacatcag ggactgtagc atggtcctca tggttgccac
    13861 gctcctccac tcggttgccg tcgggaattt cctgccatcc tatgtcaaga caatctgcgt
    13921 ggacatcaat ccctcgtctg tgacaaagct catggacagg gggacgatgc aggccatcgg
    13981 tgttgtcagt gatgccggga ccttcttccc ccttctcgaa aagcagctcg aattgcagag
    14041 cgggagaatc aacgggtaag tggcatgcaa taggggcgct cgttttcaag cacgaactcc
    14101 cactcttttt tgcacgtgca atccatcccg agtaacgcct ccagcaaacc cctgtccccc
    14161 gagagagagt aatcacggat tccctggaga atggtgcggt cgcatgttcc gcagttgtgt
    14221 gcacccctcg gcctcccgcc ggagaggggg tcacacagga tgtgtcgttc tgcacgtaaa
    14281 aggatggtga ggatactcca gagatagggg gggcggaact ctccccgttt ccagtaatac
    14341 tcaagttccg tgcccttctg gactgaacat ggattgaggg agatcatatc ggcaattccc
    14401 cggagagcat ttatggaaga aaccacgtcc tcaatcgatt cacgctctgt caggaagggg
    14461 ggttttacaa ggaggtatgt tttgacacct gcaccagcgg accgcgccgc ttttgaggcc
    14521 aaaagaaagt catcccagga aaagcccttg ttgatgcatt tttccctgat aaagtcgttg
    14581 ctggtctcaa ggcctatcgc gacatagagc gggagatcat ggctgccatc gtcaatgatc
    14641 tcacggaacg atgcaacacg gtcagtgacc acgaactccg gtctcgtctc ggcaatgaca
    14701 atttttcccc tgaccagtga cccgatggca tctcttgcag cccccggaac ctctaccggg
    14761 tcaaaaaagc tgccggaagt gtagatcttg acgcaatcga tattatccat gggaaaacgg
    14821 tctttgagcc aggagacctg ggcaagtaat agtcgtgcca gctcgccctc tcctgctgca
    14881 ccaagcctga catgccggta actgcacatg cggcagcggt tccagctgca tcctccggtt
    14941 ttcaggatga cggtgagcgt tgaaagaacc ctgttaccaa tccggtctga tcctgtccat
    15001 gccgcatagg gccttgcctc gttcaattct ccggccacgt gggtactata tgggctccct
    15061 ctcctatttg acattccccc tcccgtattc ctttttttcc gggagtccct ccaaattcat
    15121 ggaaaataat gtttattgtt cattttccgg gacatggaac agggatcaga taccagaaga
    15181 ctattcaatt ctccagacgc aatactaaaa aagcaccgcg tctccacaaa tcgaatacca
    15241 aaagattatg cattgaatcc ggagacgccc tcttgcggaa aggaagtgtg ccgaacaatg
    15301 agctgcatga atatgggacc cacaccacgc accgttgtgg ccatggttat ccttttactg
    15361 gtctgtacag gcctcgtctc ggcgtacgag ctgagtatct ctgcaccccc gacgatccag
    15421 aagggcaaac cgctcgtcgt gaacgggacc tccaacattc ctgcaggaat ctctgtggat
    15481 atcgtcctct cgcggtcgga gtatacgaca gaagaaattg cccgaaagac cgtcacactc
    15541 cagtcgaaca aagaattttc cgttgtattc gatacaaaag atctccagaa gggccagtat
    15601 aaggtggaag ttcccagcat ccaggggtat gcattcctgg gaggatcggt cacactgagg
    15661 attgtccagg tggtagatcg gtctgatgag gtgacgatca agtccatgcg gacgcaggag
    15721 atggatggca ccctcgagat tgcaggggtt atccccaaaa atccaagttc cggtgtgcag
    15781 gtcgaggtcg tcgggcccgg ggacgaggtt gttttcggcc cacagttcat ctcaacgtcg
    15841 tctgacggat cgttttccct gaacgttccc ataacaaagg caggcaggta tgagctgagc
    15901 atcacggaca gcaaaggttt catcgggacg tacctgttta ccgtaaacga aagggtggag
    15961 actgttgcca ctctggcaac cacccccgcg attctggctg caatcaccgc aacggccccg
    16021 tcaagcgccg aaaaacccgc tttttttgtc attacaggtc caaagggaaa ggtgaaaatc
    16081 tcaacatctg cagggaccga ctgggtcatt gagtatgcag accagagggg cattatccag
    16141 aaggttaact ccaaaggcca ggtcgaacct gaagaaattg cagtcgatgt atccggggac
    16201 tcgctctttc tcaaggttta tccctaccgc ctctctgaca ggggagacgt gactgttttt
    16261 gtcgaggggg cagaaaaaat cggagtagca acggagattc ctcccgtctt tgcaccgaca
    16321 accacaccga cgacgaaatc cccgttacct ctcctgcttg cagttattgc atttgccctc
    16381 atggctctcg ggaaaagata ccggtcatga ccccccccat tttttcgtga atacaagacc
    16441 ctggtttgtc tccctgcagg gaagtaccat catatgaacc gggggccgtt tgccctgtga
    16501 attaccggga cgggttaggt ttttgatggc ccaaaaccca taataaatag cgggccgggg
    16561 tagtctagtc cggaaaggcg gtggccttga aagccactgg tgcctggcac ctcaagagtt
    16621 caaatctctt ccccggcgtc tgctccagga gttcaaatca cagaaccggc atagacagaa
    16681 gtatcagcgc ctgtgaaaat ttccagtggc cggttaccgg ttttctcgaa ataactcgtt
    16741 cacgtctgga ttctttatta cgcaacatcc ttttcgtgaa ggtggattac cacaccatga
    16801 cctctgtatt tatcttatta tcccttccat ccctgacatg agtgacatgg agagtgacct
    16861 caaaaggggg atggttgcat ggtgcaggag acaggggata cccctggtgg gagtggccga
    16921 tgccacccgg tggcataccc cgccttttgt gccctggatg cctgaagatt ttttcccgca
    16981 gtcaatattc ccgggaacgg aatcagttgt ggtcatcggc cttcccgtgc acctcccggt
    17041 catcgaaacg acaccatcca tcttttacca tgagcattat aacaccctga accgcctgct
    17101 ggaccagttt acttaccaga ttgcagagcg gttcaaccag gcgggatatc cctcggtctc
    17161 tctcccccgt gacgggtatg gaagcatcga ggtcctccgc gaatcgcctg ttgctttctt
    17221 ttcacaccgg catgcagcat tccttgcggg tttggggacc tttggactga ataacatggt
    17281 gctcacacaa ggatacggcc cgcgggtgcg gttctcgtca gtctttacca ctgcccgtct
    17341 tcctcccgat cccctgatga aaatagatct ctgcacccgg tgtcaccgct gcgtggagat
    17401 gtgcccggca agggcgcttc cggaagatcc ttacccgctg ggaattacca ggaaggaagc
    17461 ctgcacggaa tacagtgcgg ccctgttccg gaggcatgca tctccctgcg gggtctgcat
    17521 caaggtctgc cccgtgggcg aggatcgcca gcactttggc cggactgacc cgggtatcta
    17581 ttcacggcaa tacccggacc cggcccttgc gcgtgcatgg gcccatgtac ggaggtatgg
    17641 tctaaaaggt gcaggcaaag aggtatgagg acggcggaaa ccaccccttg cctgtcaacg
    17701 gggaggtttc cctgtgatca gcttttatca tggtaaaaga gcaagatctc tccaggaggt
    17761 tcctgggatg tgtattgctg ttcctgcaga ggtaatcgag atcagggagg gaaacatcgg
    17821 cattgtggat tatggcgatc ttcagcagga agtccgcctt gacctcgtgg acgtgaaagt
    17881 cggtgatttt gtcctggttc atgttggatt tgccatccag aagatatcgc gcgaagaggg
    17941 actcaagacc cgcgagatct tccgccaggt gtatgccgcg atgcaggaat ccgactaaaa
    18001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn agacccgcga gatcttccgc
    18121 caggtgtatg ccgcgatgca ggaatccgac taaaaatttc acaattccct gcagttttca
    18181 gattggttcc cgcttcatgc gggcaggtga acatctttat ttcattggga ctgcccttcc
    18241 gatgagcgat tgcgcatcat gattgaaaac cacgaggtga tcgtgggtgg aagaagcgtg
    18301 accgtagttt ttgatcggga gaatgggact ctccggtttc gtgtgcgttt caggagaatg
    18361 ccgtctaaaa aggagcatag tttttttaaa ccaacatgga gggcaatatg cttatcttct
    18421 ctgacagaga aaaataaaaa gagataatgg agaggacgtg ttaaaaatgg acaaaacagg
    18481 cgttgcaagt ctcattgcag gaattattct tctggttctc ggagcatacg gggtatggat
    18541 attcctgccg gacgtaattc tgtttttgaa aggcgttatc ggaatactcg caatcctgat
    18601 tgggattttc cttgtcatat tcggggtaat actgataaag gattgaaacc aaacttttct
    18661 ggaaaagcaa tgcccttttc caaaggcatt taattgaaaa atagaaatat ttctccccgg
    18721 aacgggaaac gatacggatc cggggaatgt ggaaagctcc ggggtattgt gtatcccccg
    18781 ggatcggtgg tcgcatggat agaatgaagg tcctggtggt gctccttgtc atctcccttt
    18841 cagggaatgt attctttctc gtgacaggcg ggaataaccc cgtatccgag aaaatcagcc
    18901 agtccctcct gtatgcatac caccaggcat tccctcccct ggacaatgaa accatttccc
    18961 tggcggagaa cgaaagcaac cagacctata acaatacgac ggaggccgtt caatcgggtg
    19021 gtgatgaaaa ggagttcact gcccgggacc ttctcctcat gatcgagaag aacgagatct
    19081 ccgacgagga aatcctgcag atgctcctct ccctggaaaa cgaaacagtc cctgcagaag
    19141 aacaggaagt caatgtaacc ccgacaccag acccgaacgc ctggaaggta tacgagagtt
    19201 cgaaatggca tttttctata ccctacccac caacatggac ggtaaaggaa gggacctcgg
    19261 cgagctctgt ggtcacgatt actgcaccta tcgaaacaaa atgcagttct gaatcaaagc
    19321 agtgttacca gtatgtggct tcactctccg tctcgatcga taccaatccg ggaacgggag
    19381 gcctggaaga gtacttcaac aagaagatag catcgctcca gcgccagctt gcaattaccg
    19441 cgaccagtaa gagtgcgaca acgtacatat cgggtgaaag ggcttactgg atcgaatact
    19501 ataccaggga ttcacgaggg aacccgtcga agcgctacat gcaatatttt gcactcctcg
    19561 acaagaaagt ctacatcctg acatattcag gcccctattc aacgaacgag aatgtctatt
    19621 cacggaacaa gggagatgtc cagaaaatga tagaggggtt caccgtcaaa agggagtacg
    19681 tgatcgtata aagataaaga tagagatttc tcctcatttt atcatgaatg tttaattttt
    19741 gaataatctg catctccatt gacaatgaaa cggtgctgaa aaatcccggt tggtgaaaat
    19801 actttattga acaggactct ccccaaaatg cacttatcac ggaaattcac tgttgtacgg
    19861 gtggaaaaca ggtcgttttt gaaccgattg agaaaataaa ggtttaaccg gagaaatgga
    19921 aaatactaga acttttccac gtcttcggcc ttgattgtct ttcttccttc agaagctgct
    19981 gcattagctg cttttctggc aacttcagca atgtattttt cagtcctggc aacgattgcc
    20041 ctcgtgccgt ccatgctgat cctctcggca ccactgttct tggcaatcct gacgactggt
    20101 gcgataggga ggtcaaacga gctgctcctg gttgactttg ctttcttctt tacaggtgct
    20161 ttcttaacag cttttggcat aaacacgtgc ctcaaaaaac cattgaggtg gaagtattta
    20221 aatataattg atcccggcag ttcgaaacgc gattatatcc atcccggaaa agaaccgtgc
    20281 atccccagcg ggaataccaa aagagagcgg aatggatcat tccctccggg gtaaaaatct
    20341 tcataaatgg ttgaaatgac taaatcacac caaaaaaggg tactttcagg tcaactgatt
    20401 cccacgacaa cgtggtgcag tgtatcgaca gttgcccgaa gcgccctgcc agcatcacgc
    20461 atgtggtggt acacttccct ttttttcatg gcgcccatgg catccttcgt ctggaaaagc
    20521 cgggccatgc tctcaatgta gatatcgtca atggtgtgca tggcctgcct tgcagatcgg
    20581 atccgcttct cgatgttttt tgtgtccgag ccgatagcag taacccccgc ggccatacat
    20641 ttcgtacccc tgaggagttc ccccgccatc tgcacgatgg gaatgtcagg ttcgaccccg
    20701 aaggcataca tctcccgggc tgtctcatag gagtaattca cgatgtaatc catctggcgg
    20761 gacagggtgt aaatgtcctg gcggtcgaag ggtgtcgaga atgaatccat gagtttttcc
    20821 tccatctcgt accgcatccc gtccaccgtt gcagccatgt accgaagttc cgccggatct
    20881 ccgacaggct cggccttgag ccatctgaca aaggcttcaa cgcattcaac ggttttttct
    20941 gcctgcccgg caagcattgc ctcaaaatcg tattcctcgg ggaaaatcat ctggaataat
    21001 ccctttttct tcactttctt gataaacgtc ccttctttca cggtgtcacc tcatgaagga
    21061 gaagagcaac gatgctgcac catatgctac aatgatggtc gcaggaatag tcaggaccat
    21121 cactgtgaca atttccctgc ccacgcgcca ccggactttt tttgggttct cggcagcgcc
    21181 taccccgatt accgatgcag agatgatgtg acttgacgat acaggtgccc cggcaagggt
    21241 ggaaacagca aggatcgtac ctgaagacac ctgggaatcg aaagaatgga ctggctcgat
    21301 cctgaatatc cttcgaccca gcgttgtcat gatgcgccac ccgccaagga gcgtgcctgc
    21361 accgagaagt gccgcacaga gaacccgggc ccagagcggg acagagaaaa ccgggacgag
    21421 tcctgaataa aagaggacaa gggcaatgat tccaagctgt ttctgcgaat catttgcacc
    21481 gttgtaaaaa gccatgagtg ccgtggagca ccagttcagg cggacaacca gcctgttcac
    21541 tctccgtttt gcattccgga gagccagacg ggaaagtgac cgcattatgt atccacctgc
    21601 aaggccgagg agaactgata ccacgaggaa tataatgacc ccggacactc ccgacatatg
    21661 gggggaagga gaaagcaggt cggtgatgcc ccagttaata cccgcaggtc caccgtgtgc
    21721 cattccggcc ccgataaggc caccgatgag accatgcgtg gaggatgacg gcaggcccca
    21781 ccaccatgtt acgatattcc atgcagtcgc tgcgaggatt ccggagagaa tgacaagcac
    21841 catctccgga ccatctcccc cggcaaggaa cccggaaatc gtgagaacga ctgcagtccc
    21901 accaagaagg gcgccaatca cgttgaacaa agtgacaaag atgatcccct gccggggagt
    21961 tgccgaccgg gaggcgatga aagtcgcggc gatagtgctt gcgtcctgga atccgtttgt
    22021 aaagcaaaag gcaagggaga tgagtatggt gagtaagaca gcctcgtaca tgccgggtca
    22081 ttctcaaact gtttttccca aaaacatccc tttctgttcc atcaggggat tcccgctttt
    22141 ttcaaggggg tataaccagc cgggttctgc ttccgtcagg ttaatagagt gcccggtgaa
    22201 ccataatagt agtgtttctg attatctttt caccatgtcc cggggaggta atcacatgcg
    22261 cctgagactg aaagatgaaa tggagtacgc catctggaag attacagggc tttctatccc
    22321 ttacaacgag aacgtcatac cctgccttgc gcagaagatt gcgctggaga cgggagagga
    22381 ccctggagag gtcagcatga cactatcagc ccggatcaag gagataatct gggaagatgt
    22441 ctcgaaccat tacagggtaa gagaaagcaa aaacgaagta cttgaacccg catacgagtg
    22501 aaaacgggtc ccggaatcat aagtcccttc ccggtcgggg aaaacatata ttgacaccgg
    22561 tcgaacgtaa aagggattgt tccggggtag aaccatggaa aaaaattctg gttatgcagt
    22621 gtacctgtct ataaccgcac tccttgcagg cctcatcttc ctgggcgggt gcgtgcaaca
    22681 cgggatcacc tctcccggca ataccactcc cgtgccggca actctcacgc cgggggtcac
    22741 ccacccgggg gggaaccagt tccttgggac ctggcagcat tttggaatta tcggtacaaa
    22801 cagggttgca atccggtttg attttctttc gaacggtaca ggaaggttcg acctcgtcgc
    22861 accagacctc gatcctccat tcagaaaaac catggttttc tcgtgggagt cagagggtga
    22921 ccggctctgg cttggctctt caaacgagaa acaacacctg gatatccggc acgatgcggg
    22981 gaccgatcgg ctgaaggtta ccgccgataa cgagtccggt ctcttcatcg gtgaggattt
    23041 cgttccggga ccgttctact gggagtttac tcgcgcagag gaacagagct gattttcttt
    23101 cttacatccc cttttttgtt ttaccggcaa ggggccttgt gtgccggata cctggttttc
    23161 gaaaaggctg tcttttggtc tccccgattg ctgtcaaacc agattttttt tatccggtca
    23221 aaaaggatta gaaattacct gctttcgaac cggatgacag aaagagaatg ctgctatggg
    23281 gattcgaacc ccagtcgcgg gcgtgagagg cccgcatgat tggccggact acactatagc
    23341 agcaactgcc tgattaaatg ggtcttgggg acacataaaa ttgttgttga ctgtttacta
    23401 tcctgaaatg gggagcgtga ttgacgtgtt caacttcctg tttttccgac cggtggctcc
    23461 ttttgccttg tcgttgcgtc ggacccacag ttatatctct gcgatacagc cactgatata
    23521 ggaaaggcgg atggcgggac tggaagaaca gattcgggaa ctcgaagagg aactgcagag
    23581 gacaccctac aacaaggcga cgtccaagca catcgggaga ctgaaggcga agattgcccg
    23641 gctgaaagac gaggcagtct cccgcgcgat gcgtgccggg ggcggaagcg aagggtattc
    23701 tgtccggaaa tcgggtgatg caactgttgt gcttgtcggt ttcccgtcga ccgggaagag
    23761 tacgcttctc aatgtcctga cggggacaaa aagcgaggtc ggtgcatatg ccttcacgac
    23821 ggtctcggtc gttcccgggg ccctcgaaca ccgcggtgca cggatccaga tcctcgatat
    23881 cccgggcctg atcgcgggtg cagcgatggg aaaggggagg ggcaaggaag ttatcggggt
    23941 tgtcaggagc gctgatctca ttgtcatcct cgtggacatc tacaatgcct cccacgtcga
    24001 cgtcctcctg tcggaactgt acgatgcagg aatccggatc aaccgcccca aaccagacat
    24061 caccatcagg aagacggcat caggtggcgt gaggatgaac catgtcggtg tgctggacct
    24121 cgatatcgag gagatacggg ccatcctgtc cgagcacagg atggtgaatg ccgatgtcct
    24181 gatcagggga aacgcaacgc aggaggatat catcgatgcg atgctcggga accgggtcta
    24241 tatccctgca ttcgttgcag tcaacaaggt cgatctcgtc gacgaagcga cacgggaagc
    24301 gatcaggaac gatatttccc aaagattcgg gtccccaccc atcctcatct ctgcccatac
    24361 cggttaccac atggaggaat tcaaggactg gattttcgat acactggggt tcatgcgggt
    24421 ctttctcaaa ccccagagcg gggctgccga cctcgaggaa cccctcatca tcaggtcggg
    24481 gagcacggtc ggtgacgtgt gccgccggtt gcaccgcgac ttcgtggagc gtttccggta
    24541 tgcgcgggtc tggggagagt ctgtcaagca tcccggccag agggtcggcc tgtcccacaa
    24601 gttaaaggaa ggcgacctgc tctccatcat catnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24721 nnnnnnnnnn nnnagagggt cggcctgtcc cacaagttaa aggaaggcga cctgctctcc
    24781 atcatcatcg aacattagga gaggttctgc ccgaaacaag aaacgtcccg gttgcagttt
    24841 tataaaaatc ggactgtacc aggggtgata attcctcctt tgaccagccg ggatgtaatt
    24901 gggaaagagc aacgatacct tacacctttc cctcctgaag ctgcaaaaaa tactttttgt
    24961 gtcacccttt caacgcacgg acgatcgcgc cggcaaattc agctgcggca gccgggccat
    25021 ttgccgtgat gatgttcccg tcggtcacca cgggagttcc tgcgagcctg gccccgcctt
    25081 ttaacatctc tttggtggag gacgggctct cgtaacatgt cgccgatttc cctttcagta
    25141 tacccgcatg ggccagcacg accggcgaga ggcatattgc tgcgatcagc ctgttgttct
    25201 ttgaaaagta tttgacgagc tctaccagca tgtcattgtt ccacaggtgc acaggggacc
    25261 ctgtcccccc gatgatgacg atcccggcat aatcggaagg ttccacctcc tcgagggaga
    25321 gtgaagcggt cgcccgggca ccgagcatac ccctgcactg tcccctccgc gtggaggcga
    25381 tgtcgaaggt gattccagct ttttcaaatg cctcgagggg ctttgcgagt tcctcgtccc
    25441 tgaaattctc cggagggatc acgacaagga ctttcatagc tgtaaaaaaa ctctcttggc
    25501 agtaataagg gtattgccgg ggctgggaac gacccctgcc gtgtgtcacc gggtgtatca
    25561 gggctggatt tttgagagaa gaatggatta gaaaggacat tctctcctgg tgcgtgctgc
    25621 gacaagtcaa ttggtctttt gagaagggct ccgcattttg ccggcggtta cgaacgattc
    25681 cgggtcaggg cttcgcggag tacagaatgt ggcgcaatcg tcttgacagc ggtaccgctg
    25741 aaatgggccc gtgatgcttc gtaccccctg ctcctgaggg aatggatcac atcgtcgatg
    25801 gggggagggg agatatggaa atagcgggcg agaccgtgat agtcgtaatg gtgggggata
    25861 tcaagttcgt ttcggcacgt gtccaccagt ttccggagtt ctccccccag ccggaatccg
    25921 cttgaagaga tggattcatg gagacggtcc aggaggttcc tgtcgtggag aggccctgtc
    25981 cagagtggcc cgacaggtac gagcgcattc ctgcaatacg ggcattcttc atgggatggc
    26041 aggatcccgg tggtatgggt ccggaatatg caggacgggc actggaggac gtatcccatc
    26101 atgctcaagg atctgtctgc cattcgggct ccgcgaagaa ggcgcaggtg gacacggcag
    26161 taatgctccc gtgcatagga gaagaggggc tcgattcccc ggtcatacct ggcagcttcc
    26221 ctcgcgataa atccaaggag gatccggagt ccggtctctg catggtactc gttgttcagt
    26281 gcgattgcaa aataccgtcg aatcccggca ttcctgtgtg caccgcagag gggtgccgtg
    26341 tctgttgcag tcacgaagag gaacctgcca caccccttca gagccgaatc gatgaaaggt
    26401 gcggggctgc cgaaagggtc gatatcaacg gtctcaaaga ccctcccgga gaggagacag
    26461 tttgcgtcgg aagagaccac ctcgacggga acccccagga tttcgctgtt ccggcggatg
    26521 agatcggctg cctgcgggtc gcggtcgttg atggtcaccg ggacctcgca ctcctttgca
    26581 atgcgtagtc ccctgacacc tgttgcgccc attgcatcga ggtaacggga gaccgggaga
    26641 actttggaga ggaggaccgt tgcatcccgt gcaagttcca tccgcgggtt gtagaagacc
    26701 ggtgccgatc cgggggggaa aggatggtga gggtcggtgg ccgggactaa aaactttatt
    26761 cgtccctcct ctgcccaaac atactccata gcgggagaat gtggcggttc gacacgctta
    26821 taccttctca tcggcaatga gttatggcag ggcgtgtggc ctagtctgga cagggcggca
    26881 gcctcctaag ctgtaggtcg ggggttcaaa tccctccacg cccgctgttt tccgtggttt
    26941 gataacgatt ttcccgggag ggataccctt tttgtgacag gataataaca gatatgcagg
    27001 aggagtgcct catccttccc cgatccgggt atatccaggt catccgccct gtcaacgccg
    27061 tcctcgcagg tcttgccggg atcgtcgggt acctgatggc gacgggaacc ctcattcccg
    27121 gggtcatatg gatcttcctt gtcgttttcc tcgttaccgc ggggggtaac gccgtcaatg
    27181 attactgcga cgtggagatc gaccggatca accgtcccga tcgacccatt ccttccggcg
    27241 cggcagacag ggatgcagtt ctggtctgtt ccgcgatcct tttcctgtgt ggtcttgccg
    27301 tctcgttcac gatgaacacc ctctgcgtgg caatcgcggc cttcaatacc atcctcctcg
    27361 tctggtacgc aatcagcctc aagcggactc cgggggccgg gaatattgcg atttcatacc
    27421 tgacggcctc gatattcgtc ttcggggctg cctttgcagg tgccggtggg gccatgaagg
    27481 tccttcccat cgcccttgtc accttctttg ccatgctcgc ccgcgagctc tggaaggatg
    27541 ccgaggatgt cctgggtgat gcggcgggcg gggcgttgac gcttcccgtg cggatcggag
    27601 tataccctgt catccggctg gggtttgtat tcctcgtggc tgcgatatgt gcgagcctcg
    27661 tcccgtttct ctggtgggga ctgccctacc ttgcgggaat cgccgtcgtg gatcttctcg
    27721 ttttctggac tgccttcagg gcactctcct gccggacacc cgaatgcctg aaggggacaa
    27781 gggctaccac actcgtcaag tacgccatgt ttacgtcact cgtggtgttc tccctcgcgg
    27841 ccctcttcct gtgaaggagt ggaagaaaaa agggcttctg aagcctcatg gggtatcctt
    27901 gcggggtcga cacccagcga cgccacctcc atgaccttct cccagtcgac actcgtctcc
    27961 acgcacccgt ctttctgcgt gacgactccc atcgagacaa gacccatctt atcggacatc
    28021 tcgagaccgt ccttgacttc ggcgaggcat ccgacaccga tgatggctct cgggcggtat
    28081 gcccggacca tgcgcttgat gaaagaggat ccgggcacga tgaagacacg gtagcccatg
    28141 gccgagagta ctttcctcca gtaccctata ctgcatgacc cgcagcttct gcaggcgaga
    28201 ccttcgggcg agaggtgggc aggacacctg gacgaacgca ggcactgggg aaagaagatc
    28261 gccctctctt ccggcgggat ctctgcgaag ctctgcttgt gcatggtatt atggagcgtg
    28321 atgaagaaag tgagaacctc gctgtcttcg agaccgaaga ggcggaagaa tgcttttgcc
    28381 aacccttcga cgagtaccat gccggccttg acaaaacggg gaaggatgag cctgcccgta
    28441 ttgatcgaga cgatggatat ccatacgaga aggagggaga agacgaggag accaaagaga
    28501 atgaggaggg tgatctcgcc cacgaggaag atgatacctt caatggtcac aggtgcaaaa
    28561 accattgcat tacaccggat ttctggatat taatgctttt tcaagtgcca tccagtcggg
    28621 gggcggatga aagacgccaa tatccgtgat gaatgcactg accagatcgt ggggagtgat
    28681 atcaaaggcg taattcttta ccgccacgcc atcgggaacc acggtagccc tcccgcacga
    28741 tgccacctct tccctcgccc gttcctcgat gacaacgtcc cgggcagcat ggatgggatc
    28801 gaacgtggtg acaggtgcag caacatagaa cgggatattg tggtacctgg cacagaccgc
    28861 gtgcatgtat gtccccacct tgttgaaaac agcatcccgc gtgatccggt cagccccgac
    28921 gatgacgagg tcgacctcgt gacgctgcat caggaaggca gcctcggagt cggggatgac
    28981 ggtgacagcg atgccgtccc tccggagttc ccatgccgtc aggcgggcgc cctggaggag
    29041 cgggcgggtc tcgcacgcga tgacagaaac ctgcttcttc tgcacaacgg ctgacctgat
    29101 gacaccgagg gccgtacccc attccctgca ggcgagcgcc ccggcgttgc agtgtgtcag
    29161 caccgtgcat ttttcaggaa tgagtgcggc cccgcaggtt ccgagctcgt ggcatgaccg
    29221 tgattcagca tcggcgaagg ccttcgctgc agcatgtgca ttttcctttg cctctttgac
    29281 cgaacccgca ctttcgacgg cctccatgac caccctgacc ccgagggaga ggttgaccgc
    29341 cgtcggtctc gcagacctga tcttttctgc ttccctgtac agcctccgga gaaagagaga
    29401 atggtcacgt tcgcggatct gttttatcgc taggagcacg ccgtatgccc ccgcaatgcc
    29461 gagtgccggc gcgccgcgga cctcgagggt ccggatggcc cggacaagcc tgtccgttgt
    29521 cctgcaccgg acgaggcggt agctgcccgg cagacgcgtc tggtcaatca ggatgacgtt
    29581 tccggtttca tcctcccacg aaatggtctc gatggatttc atcggcactg actgtttctc
    29641 gaagcatcga tgaacgcacg catcgcagcg gccccggagt gggcaacgca gtccgggata
    29701 tcccggggtg cggtcacagt gcccgcaagg tagatgccgg gtcgttctgt tgccacggta
    29761 tcgacctttt cgttgagtgt cctgaaaaat cccgtggact cccgggggag accgagcatt
    29821 cctgcgagat cctctgcgtc aggagccggc tcgaggccgg tggagagaac gacgagttcc
    29881 gggttgaggt tgagtatctc tccgttctcg gtgttctcca cgcgaatacg gatgctatcc
    29941 ccctgccctg tcacttcacc gggcatcccc cggacgaaat gaacccctgc accgattgcc
    30001 ctctggtaat attcctcgta ccccttgccg tatgccctta tgtccatgta gaggatggtc
    30061 acgtcgatgc cgggatattt ctcgcggagg aggattgcgt tcttgattgc atacatgcag
    30121 cagacacccg agcagtaggg ccttccgaga gggacgtccc tcgatccgac acactggatg
    30181 aagacgaccg aacgcggagt ctcccccgtg gaaaggcgcc tgatctttcc gcccgtcgga
    30241 ccgctcgcgt tcatcatccg ttcgaactca agacccgtga cgacatcggg gagggagagg
    30301 taccggaact ggtccttttt ccgggcgtca aagacttcgt agccgcacgc gaggatgata
    30361 ctctgtgcat gcacggtgat gtccctctcc cgatcctcct tcaggatggc ttccctgccg
    30421 cagatatcgt agcaaagtcc gcattcgatg cagtgatcgg tgtccctgac cacgatgtcc
    30481 ggcactgcct ggctgtgggg tttgtatatg gctttccgga caccgagtcc ggcgtcgaac
    30541 cggttgtaaa cctcgacagg gcacacttcg atgcaatccc cgcacccgtt gcacttttcc
    30601 ggatcgacga agcgcggcat catcctgatt gtgacatgga agtctccggg tgtcccgctg
    30661 acggagacaa ccctcgcaca tgtcatggtg cgtatgcggg gatggcggta cacgtccatc
    30721 atcttgggtg agaggatgca catcgagcag tcatttgtgg gaaaagtctt gtcgagcatc
    30781 gccatgtggc ccccgatgga cggctccttc tccacgaggc agacatcgat accatggttg
    30841 gcaaggtcga gggcagcctg gatccctgac acgcctcccc cgatgacaac gacctcagtc
    30901 atccctgtac ctcccggcca tctcccagta gacggatgcg ttcctgacga tatggtcctt
    30961 ctgctcttcc gtgacctgct tgatgacctt gcccggcacc ccgacgacaa cggatccagg
    31021 cggaatgacc gctccctcgg tcacgacggt cccggcacca agaagcgtgt ccctgccgac
    31081 aactgccccg ttgaggacga tggcacccat cccgacgagg acacgatcct ctatcgtgca
    31141 cccgtgcagg atggcaccat gaccgatgga gacctccctt ccgatacgga cagggaaccc
    31201 ggcacttgtg tggatgacgg cgttgtcctg gacgttggac atgtccccaa tcgttatcct
    31261 gtcacggtca ccccggacaa ccgccccgaa ccatacgctg acggagtccc ccatttccac
    31321 gtcgccgagg actgttgcgt tcgcggcgat gaaccggcca cctgttccgg ctttaccaac
    31381 agccataata gcattaaaag ttcactatca cgcacaatga aggttatggt cgggggtacc
    31441 ttcgacccct tccacgacgg ccataaaagg ctcataacac ggtcctttga actcgccgga
    31501 cgtaacggaa cggtcgtcat cggcctgacc acggatgcat ttgcatcccg gaaagtccat
    31561 cctgtacgtc ccttcgagga aaggagaaag gcacttgaag gtttcatccg gtccgagggt
    31621 tttttggctg cctattcgat cgagcctctc aacgaccggt acgggtcggc gctcgatgca
    31681 gatttcgacg cactcgtcgt gagcgaggag acgcttcccg ttgcacgcga aatcaacgtc
    31741 ctgcggcggg aaaggggaca ccggaaggtc gatatccacc agataacctg tgtccttgcc
    31801 gaagacggga agtggatatc cagtacccgc atctaccgcg gagagatcga cgagcatgga
    31861 agggtcatca ggagggaaag tgaaaatgcc cgggatacag gtagaggttc gcattcctga
    31921 aatgattatg gttggtgtta caggacgagc aggatcggtt acgatacatt cgcatttcat
    31981 gattcgcgtc ccacccgccg gtttcaggga tccccgggat cccccgtgat gcgaatgcat
    32041 tgaacccgga gtatcctaca aattcataac ccctcctgtg caaggagtga ccggtactct
    32101 cagcatcact tttcgtgcac gcgggtcctc ccccgtgcac acctcttccc gtgtcgttgc
    32161 gggcagggca aaggtcggtt tccagtgaga aaggtagaat ggtttatcca tctgagattt
    32221 ctggttcaac ccgatacgga agaatgcagc gggccgggca ggatgagcaa accactttcc
    32281 cgttgcacaa gacaatgagg taaaaatgat tgtgtgggtt accggatttt ttcccttgcc
    32341 agaaagaggg ctacacctga tgcgaggagg gccatgaagg gaaaggtggg tgcagccggg
    32401 gtggtcggga cggttgtggg acttgtcgtt gatggcgttt ccgtcaggaa ttttaccatt
    32461 gccatggctt catctgcttc ctttgtccga ccgaggctgg agagcgcggt tgcccggtca
    32521 atccaggcct ccgagagccg ggggtcgagt tcgatcgccc ggttggcagc ctcgagaccc
    32581 tcctcgaacc tctgcaggga gatgagtgcg ctggccttgt tggtccatgc atctgcctga
    32641 ttctcgtcga tggcaagtgc cctctccgag gcttcgagcg attcgttgta ccttcccttg
    32701 acgttcagga tacccgcttt cgtgatccag gcaagcgtga agttctggtc cagcgacagg
    32761 gcctgatcga tcgatgcaag tgcgtcgtcg aacttttctt ccatcgcgag gtcaacaccc
    32821 tggttatagg ccgaaatggc gtcgaggggg ggagctgcaa gacaatgagc aacacccgtt
    32881 ccgaggatgc agagggttaa tacaagagca agtcccttct tcatgaaaaa taccttcctt
    32941 tacctctatt aagccatata gatggaaata ctttcttctt tgcgggagga atgcagggca
    33001 gggaacatga attctgcccc ctgtatgaag gggtgaaacg gccgggaggc gatgtgagca
    33061 gggactcctg aatcgtccac gggccgaaga tgtcaattta aggggagata tcaaaggagc
    33121 gtcatgggaa gcctggttga ggccggaagg gtccttcgtt tattattctc tttagaactt
    33181 tgcaatgaaa aagaactggg gattattcgt agcacactgt agtagtgaca ggaagcgaat
    33241 aattttctgg gggcaaatga aaaagggagt agttcggatt tttcagaggg aatgttccag
    33301 aaatttttct ttaatggtgt atttccatct tttaaatagt cactcgtcgg tctccctatc
    33361 cgcaattccc atgtgacgta aacgtaaata tgtagaatta attagttaaa aaattattat
    33421 ttttattatt tataaaaata aaaataaaat atttaagaaa tggtatgcaa tataattcca
    33481 cacatgtcac ccgtagcccg ccgcaccatc ctccccttca cggccattgt cgggcaggag
    33541 aagatgaaga aggccctcct cctcaacgcg gtcaaccccc gcatcggcgg cgtcctgatc
    33601 cggggcgaga aagggaccgc gaagtcaacg gcggtgaggg cgcttgccga actcctgccc
    33661 gagatagagg tcgtcagggg ctgcccgttc cattgtgacc cgcacgaccc ccgggagatg
    33721 tgcgaggact gcgcgggaaa gttttcacgg ggaaataccc tcgaggcaga atggcagagg
    33781 gtcagggtgg tcgaccttcc cctcggcgtc actgaagacc ggctggtggg gacgatcgac
    33841 atcgagtgtg cgatcaagga ggggcggaaa gtcatcgagc ccgggatcct tgccgcggtc
    33901 aaccggggga ttctctacat cgacgaggtg aacctcctcg atgaccacat cgccgacgtg
    33961 ctcctcgact cggcggcgct cggcgtcaac gtcgtggaac gcgagggaat ctcgttctcc
    34021 cacccgtcac ggttcatcct gatcggaacg atgaatcccg aggagggaga gatccgcccc
    34081 cagctcctgg acaggttcgg gctccaggtc tcggtggagg cgatcgagga cccggagcag
    34141 aggatggcaa tcgtcaggaa cgccgaggcg ttcgacgcgg accccggcag ggtcgcaggg
    34201 gagttttcgg cggcgcagga ggctctccgg gcaaccatca tccgtgcaaa ggagatcctc
    34261 ccgcaggtga ccgtgccgga agacattttg cgggcgctcg tggaggcatg cctttcgctc
    34321 ggcgtcaaga cgcaccgggc cgagatagcg gtaacgcggg cagcacgaac gattgcggct
    34381 ctcgacggga ggacggaggt gacgcgcgac gatgtccggg aggcgatgga atacgccctg
    34441 ccccaccgga tgcggcgcaa acccttcgag gagccccgcc tcgaccccga ccagctggac
    34501 tctgccatga agaatgcgga cgaaaaccgg cggcaggagg agaataagga gacctcccgc
    34561 ggagaggaga agggcaaggc tcctccacat cccccgggac aggggggaga agagagcgga
    34621 caaccccggc agcagcaacc gcgatcctcc gaaggagagg gcagggagag ggtctttggc
    34681 atcggtgacc cggtcgatac ccgccaaatc tcccttaccc gggaccggga cagggagagg
    34741 agaaagagac tgaacgggcg gcggatagag acttactcgt ccggcaggaa cggggcgacc
    34801 atatcctccc gcctgccgga aggctcgggg gacctggcac tcgacgccac ggtcagggca
    34861 gcagcaccgt accagcacgc aagaacccgg ggggagcttg ccattgccat cagggaagag
    34921 gatatcaggg agagggtccg cgtgggaaag gtctcggcat cctgcgtgtt tttggtcgat
    34981 gcgagtggtt ccatgggggc aatgaaacgc atggaagctg caaagggggc catattgtcc
    35041 ctcttgctcg actcctacca gcaccgggac cgcatcggca tggtcgcgtt ccggaaggac
    35101 cgggccgaga tcgttctccc cctctcgcac agcgtggacc ttgcccagaa gagcctggcc
    35161 gatcttccca ccggtggaaa gaccccgctc tctgcgggtc tctggaaggc aatcgaggta
    35221 ctcgaacgcg aaaagcagaa gaacggcgag gcggtccctg tccttgtcct catctcggat
    35281 gggagggcaa acgtttcgtc cgggggagac atccgggcgg aaatccgcaa agctgcgcag
    35341 atgctccggg agcggagtat ccacacggtc gtcatcgaca ccgaggagac acgatcatcg
    35401 tttgtgaaga tgcaccttgg atactgccgc gaggttgctg aggtggcggg agggcggtat
    35461 taccctgtca gtgacctttc acctgccaca atccgggaca tatcgggggc agagattgca
    35521 ggactcttct ccggcacgcg gttttcagct gcctgaatgc ctgccggagt gactgttacc
    35581 acctgcggta atccggaaag gaaacgaatg agcgggaggg gcgctgtccg acctcacaat
    35641 aaactggttt gaccggggca cggaacttgg tccggtggca gaaacggaag cagggatcac
    35701 tacggggcat cacgaacatc tccggtgaag gtctcttcct ttccgggacg gacggtccgc
    35761 agatcgaggc attcgttctg tgcatggaat gcagcgggga agaatacccg gatctccgat
    35821 ggggtgatca cactcctccc atgatatccc cggcaggaat gcatgggggg gcagggggtg
    35881 ataccattca aaagagattg gggggcgtgc agggcggtca cccccatggt atctgacaat
    35941 tccctcctct gaccagccat tctggcatac ctcctccggg agggggaatt cagatgcctt
    36001 ctgccatgca cgaccctggt tctcctgact cggttatgtg gtgtatgtcc gttgcttttc
    36061 gattccttga cggggtatcc cgccagtcgg gcaaaagtgc ctggtggtgc actctgcccg
    36121 ataaatatac tcaccttttt gtattaaatt tttttatttt tgtattattt tatcttactt
    36181 atttttattt attaaatatc caatccctgc cgcaggacga tggtgcggta atgcactatc
    36241 agttctcctt tgctaaagga atatactgat acccggaagg gagaacgatc ccatcatctg
    36301 gagaaaagaa ataactgttc tttcctcaaa ggaaaaaaat gtgagtttct tcctggtcgg
    36361 aaaaatgata gtcgggggtt tcaccatggc agtcggaaag aggggatagc gaacacgact
    36421 gagggtacag aggcacttcc ggcgctgttg ctcacccgca ggtttaccct gtagaaccct
    36481 gcccgggtat atgtgtgagt cgggtttgcc tctgtcgatg tcgtgccgtc tccgaagttc
    36541 cagagatagg aggtcacgtt accggtcgag agatccgtga accggactgt aaggggaaca
    36601 atcccgctcc ggggtgagag tgtgaaccgg gcgacgggtg gtttttccgg tgcagtcacc
    36661 gtgatgtatg cttccctgac cttctccgtg gtcccgtcag gccctctcac ccgcagacgg
    36721 accgaataga caccgggttt acggtatacg taggttgggt tcttcgcgag gctgtccacc
    36781 tgtccgtcgt tctggaaatc ccacatccgc agcgtgaccg gcccggtgga gaggtcggtg
    36841 aactggacgg agagcggcgc ggtgccggtc aggggtgatg ccgagaagtc tgcagtcggt
    36901 cctggctggg agagcacggt gatgtatccg gttctctcct ttgtattatc tccaccgggt
    36961 ccggagacag tgagccggat atcataggtc ccggggtcgg agaaggagaa tgcgggattg
    37021 gattcggtgg agaactgggt ccatgtacca ttccccgacc ggtattgcca ggtccgtgcc
    37081 gtgatggttc cggtggagag gtcggtgaac tggacggaga gcggcgcggt gccggtcagg
    37141 ggtgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    37201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncggtgg agaactgggt
    37261 ccatgtacca ttccccgacc ggtattgcca ggtccgtgcg gtaatgttcc cggtggagag
    37321 gtcggtaaac tggacggaga gcggcgcggt gccggtcagg ggtgatgccg agaaatctgc
    37381 tgccgggggt tcttccgcgt atccaaggac caaaacagcc ccggcggcga ccatgttgtc
    37441 accgcttcct gataccatca cgctccggta gagggccgtg ttgtcgccac cagccatgtc
    37501 accggtgacg ttgaactctt tcagcgtcac ctgggacccc gcctcgaaac ctcccgagag
    37561 gtcaccatgt gaattgccgt tgaaaatgaa cgcactcttg cctgcctcgt ttgccgagta
    37621 gaggaatgca ataacccttg cttcctgcag gccgtcaccg gaagcgccct ggaacgggat
    37681 gtacgatgtt gcctcctcgt cggagacgaa ccgggacgtc ccggcataca ggaggtcgca
    37741 ttcctcgttg atcaggacct tcctttgggg ctctctctca tcggcataga ccacgaggag
    37801 gaggctcccg tagaggccgt tcgaattccc ctcctccgcg gtcacgacga gatggttccc
    37861 tgattttgaa aagaacggcg tcacgttgta gacaaacacg cccgaggggt agttgtaggt
    37921 cccgtatccc ttcctgtcgg tatatgtcac gtccggtgta atggtctcat cgttgaagcg
    37981 ggcggtccag gagggtttgc ctcccggcgt ctggtcaaac gtatatccct ggtagagccg
    38041 tgcatggagg atggttgcat tttcagggat gtgcaggtcg gaaacagtcc agttcgtggc
    38101 agatccggtc catcctgtcg atcggtacgc cgagtctccg gtcgacaccg cgaggttaat
    38161 ccggccttcg aaggttgcaa ccgtgccgat gtcgcttccc cccgtatacc tcttgccctt
    38221 gtacccgttg ttcgcaacga ctctcgtcag gtcagcgccg ttattggttc tgtcaatttc
    38281 agggatatca ccgtcagggt ctgcctcggc ggtaatcata acggtatctc ctgccgtcct
    38341 gagaattgta tcggtgatag ttgcagtccc gttggccccg gctgcaagac cgggaaggga
    38401 tgcagtgtac agggctccgg acacgttgaa ccggactgaa aacggaccag cagccccggt
    38461 cccgttgtta aggacggtgg cactgatcgc attgggttcg ctcgcgaaga gctcattccc
    38521 gttcgtggag atcccggtaa taacgagatc agggaggggt gtccccgtca cggaaatgta
    38581 gccctgtttc tccatggtgt ccgttcctcc cggacccgtc acggtgaggt ttaccgtata
    38641 ggtccctggt gtcgtgtatg tccagaccgg gttttgttcc ctgctgtcta taatcccgtt
    38701 accatcgagg tcccatgcgt acgatgtgat gatccctgtc gaattgtcgg tgaattggac
    38761 caccaggggt gccgggcccg cagtgagatt cgctgaaaaa tccgcgtgta tcgcatcatc
    38821 ctggtattcc acgacgagaa acgcgtggct tgcagccaga agaggtgtcg atccggcggt
    38881 gctgcggatg cccgcctcgt tcccatccac aaggagggac gacttcacgt cacgggtatc
    38941 gacggccacc tgcgtccctg acgaggaacc gtagtcccag acgttcgtgg ccaccgtggc
    39001 accattccag aggaggtcac cttcggggcc gttcccggcc gggacgaagg tagtcaggta
    39061 ggcatgggtg gcatcaccgg gagcaagaac catcccggag aagggaaggt atgctgttgc
    39121 ttcctcgggt gtcgtcgcgt atcccgtgtc gtccgcaccg agaatatcaa acccttcgtt
    39181 gaggaagatc tgccgccgcg gctcgccggc cttctcatag accacagcaa gggtgaggcc
    39241 gtacacggcc aggttactcc ccgcattatc cttgtggaca atggcagtgt ttccgccggt
    39301 cgagaagtaa tccgttacgt tgtaagcgag cagaccatag acgtaattgg catatccacc
    39361 gaagttgctt ttgtcgttat accaggtctc gtaggggatg acatttccgt tgaaggtgat
    39421 gcggaactgg tccggcactt cgtttgagtt gtcccaggta tacgggacaa agagccgtgc
    39481 ctccttcact gttgcccccg gggggagcgc gaggtctccc gttgtccagg tgacggtata
    39541 atcgttccat gatgcaccgc caatgccgcc gggtttatat gcactgttcc cgctcgagtg
    39601 gagaatgcca ccgtggaggt caaaggttct cgcggttaca atatcgttct ttcccgtcca
    39661 gtaacgggca cccttgtagc cgttgtagat aacggtcttc gtcgtgctgg tcttcgcgtt
    39721 gttcccctca tttgtctcga tgaataggtt atcaggatcg acggtagctg tgtatgtcac
    39781 catctccccg gcagtattcc ggatggtcgt atctactact ggaacagtga tgctctgtcc
    39841 cgccgcaatg gggggtactg tactgtagcc ttcgaatcca tccgacgata aaacacggac
    39901 tgttgtctgg ccggaactgc cggggccgtt attcctgata gtgacgcgga ccgtgttggg
    39961 ctcccgtgca aagacatttc cagtcaccgg attcacgagg gtgatttcga ggtccggaga
    40021 gggtgttggt gcgagggata cggagagtat ggcgagaggt aacttgtaaa actgtccgac
    40081 acggtcatag gtgaggtcat tgattgcccc cggctcgatg agatccgtta catcccatga
    40141 gttataccct gcatatgctc cctggacatt ccacccggga gggacggtgg atgccgaagg
    40201 atcggccgga agaggatcac cacaccatgt gtagaagccg tcggtacttg ccaaatggtt
    40261 gaccgtgagg gttgcggact gaacagtccc ggatagacca gagaggttga atggcgttac
    40321 tcccgtgtag ggcatcccat ggtcatcagc atagtaggag tccacatcgt gcccctgatt
    40381 gatccagtaa tagacctggt ctgtatccct gtcattgtat gcgacaacga gtgtcaacat
    40441 cttgacacgg ccgtcgaaac ttgcatccac tttctgagtg accacgcggg cagaaggtgt
    40501 ccgtgaagaa atcacctgcg aaacatcgta ccacatcagg tagtcactcg tgaccctggt
    40561 acagtgatca ttgactgcga tggtcccgct ccctccttcg ccgggatacg tgtatcctcc
    40621 cggggtgtcg aggctctcat tgccaatctc agtctcgaaa gtcccgtccc catccccgtc
    40681 gaagaagatg gtggcagtcc ccgcgtaatt gttcttcatg tggccggcat agacagcaac
    40741 gtagagcctt gcccactcaa tatccactcc ttcaggtaat tgcgtaaacg tcctggtcac
    40801 atcggaaggt ccccaggcag ggggttctgc atctacatag agtccaccgg acacgacacc
    40861 cgatcggatg gtagagagcg gagttccccc gacgtatccg tctgccgaaa cagcaggaaa
    40921 aatcgcgagg aacacaaaga tcacaataac tgttgcaaga tgtgaatagt aggctgaatc
    40981 gagaaggtct ttattcatat aaatgccacc tttgttttta acatctgaat atttcataca
    41041 tggatataaa tacttatcag gaattcgcga cgggaaaacc tgaatcccga tgcaacgacg
    41101 agcgtcgcca tgtttgcctt ttgccgggat atcacacagg gaaaacacac aattgctttc
    41161 ggataaagca acctattcca ggggaaatga gaaagaagat aaaaaaattc gggaataaaa
    41221 tgggcctttt ctcaccacca ctgggtgctc acaacgaaga ccattcccct cgccgtgtca
    41281 ctgcctgcag tgttcgatac cctgagctgg acagtaaaga gaccagaacg ggtataggta
    41341 tggaccgggt tctgctcggt ggacgtggcc ccgtctccaa atgtccagaa gtaatccgtt
    41401 ggattataga gggagcggtc cctgaatgat acggtcagtg gtgctctccc gagtaccttg
    41461 tcctgggaga agagtgcaat tggttttcga accggattga ccgttatata gttcgccctg
    41521 gtaactgtat tactcccggc cgcgttggtc accgtgaggc ggatactgta agaccctgtc
    41581 tcgttgaagg taaacgaggg gttctgcgcg gtcgagaact ggacccaggt gcccgaaccc
    41641 ttactgtatt cccacttcca ggtcacgggg ttattcatgg aggtgtccgt gaactgcaca
    41701 gtcagcggcg atccaccgct cgtggggctt gcgacgaagt ttgccaccgg cttgggcagt
    41761 ctggtgacga tgatataatt catcctggta actgtattac tcccggccgc attggtcacc
    41821 gtgaggcgga tactgtagaa ccctgtctca ttgaaggtga acgaggggtt ctgcccggtc
    41881 gagaactgga cccaggtgcc cggattcttt cggtactccc atttccatgc cgtcgggttg
    41941 ttcgtggaga ggtcggtgaa ctggacgctc aggggcgcat agccggaagt gggtgtggca
    42001 gtaaacgccg cgaccggttt caccggcgcg gttaccgtga tgtagttcgc cttcaccttt
    42061 tcatcggtgc cataaggccc ggtgaccgtg accttcaccg tgtaggtgcc ggtcgcggaa
    42121 taggtccaac tggcggttgg agttgccgaa gtgtaatccg ttgtcccgtc gttgttgaag
    42181 tcccatgcgt agctcgtgat cgttcctgtg gatgacgatg catcgaacgc gaccatgagc
    42241 ggggcggtgc cggagagagg cgagccggtg aaggctgcca ctgggggagg tacagagacg
    42301 atctcgcccg tcgccgtcag cgtgttcccg gcgagggcag gaacagcgaa cagcgccata
    42361 atgagcatga tggtgaagag ggggaggatt ctactgcctg atctcatctt tttcatacga
    42421 agcctcccgt gaaggtcagt gtgatgctgt agcttcccgg tgcatcggaa gccgcgattg
    42481 cctgcttcac gaaggcggtg ccgctgccgt caacgccggc cgctccggtc aggaaatccg
    42541 cgaacgacga ggtcatggcc tgatagccgc tcccatccgt cttcgagagc tggaacgggt
    42601 tcgcgaggtt caccgtacca gtgctcatat atccgccgtt gttcgcggat gcggtgaccg
    42661 accaggccgt gccgcccgtg acgtccacgc tcaccgtgct gctgccggtc tcgtcaacac
    42721 cggcctgcat ggtgccgaag tcgatggatc cgggagacat ggtcacgttt atagaggact
    42781 caccgacgga gatgatgttc aacttcgtct cggtgtcaga gtagtccggg ccggttgccg
    42841 tgacgcggac agaccaggtg ccattactga aggtgaacga tgcatcctct gtggtcgcaa
    42901 actgggtcca ggtcgtgccg tcagcgctgt actcccactt ccaggaggtc actgccccac
    42961 cggagttggt cgcattgaag tttaccgtga gtggttcaac gccgctggcc ggggagaacg
    43021 tgaagtcgac attcggtgcc ggctccatta cctggatatg cccggtcttt gtctttgtat
    43081 cggatccccc aggcccggtt accgttagcg agacgtcata ggtcccgcgg gcggtgtatg
    43141 tgtggctcca aggacccggt ccggaaccgt ggggagaccc gtcgccaaag tccatgtccc
    43201 aggtggtaat cgagccggtc gatgcgtccg tgaactccac cgtgagcggc ttatcgccgg
    43261 ttacagggct cgcgggcgtg aaatcggcaa cgggggccgg agttgcgtat ctcacggtga
    43321 ccgttgacag gactgtcttg aaggattgcc cggatgccgg ttcataaaca agcgtacttc
    43381 cagaaccggg gatgatggaa ttcgtggcct tcagatccca gatgttgaag tcgaagtaat
    43441 tcaccggggg caccgggtcc gcccaggact gggccacgcc gttgaaggtg taccgcccgt
    43501 ccttgctgga cgtggcgagg tttctcccgg tggcattcgt gaacccggct gttactgagg
    43561 atgtatcgaa ggttgtctgg gtcgttcccg agttgatcca gtcatgcccg tggttcaccc
    43621 agtacttcac ctggtcggta tcgccgtcat tgtatgcgac cacgagggtg accgccttga
    43681 gccggccatc atagctcttc cccgtaatct gctcggtcct gatacgggca gccggattcg
    43741 tggcggtgat caggccggtc acgtcgtacc aggcctcata gtcagagaag accttggtca
    43801 catggtcgtt gagcggatag gaatttccat tgccttccgc cgcgatgtcg cagtcctcca
    43861 ccccgagggt ggtttcatag actgcatcgc cgtttccatc aaaggagatg gtctggcggt
    43921 gcccgtagct gttgctggca gagccggagt acgtggtgac aaagagccgt gcccactgga
    43981 tgttcctgac ggctgacgac gggatgctga agggctggtc gaactcacgg aacgtaattc
    44041 cggatgcggg ctggttgccg aagggaaccg tctggaaagc acccacatag aggtcccccg
    44101 acacggtgcc acttgccacc gtggtcagcg gttcacggcc acctgagacg gcgaagaggt
    44161 gggtctttgt ctcgtcatcg ctcatggcgc cctttgagac cgtgagccgg atgtcgtagg
    44221 tccctggtgt cgagaagctc tgcgtcgggc tctggaccgt ggagaactct gtccagctgc
    44281 cgtcatagtt tctgtactcc cacttccatg ccgtggggtt gccggtggaa gtgtcggtga
    44341 aggtcacgga gagcggcgca aggccgttcg tggtggatgc ggtgaattgt gcgaccggcg
    44401 gagccatctc ggtcacggtg atataagcct gcttctcctc gggatcagat cctccgggac
    44461 cgttcaccgt gagccggatg tcgtaggtcc cggctgcagt gaaggtataa gacgggttca
    44521 catccgtcga gaactgcgtc cacgaacctc cgccggtccg gtactcccag ctccgagagg
    44581 taatactccc gatggatgca tccgtgaact gtacctcgag cggggcatcg ccggacgttg
    44641 gggtcccggt gaacccggct actggtgccg cctccgtgta ggtcaggacg aggaactgct
    44701 gtgccgctgc catggctggc gttgcgcctg ccgtgctttg gataccggcc tcgttggtcc
    44761 cgctaagata cgacttgaca tcccttgtat caacggccac ctgggtacca gagaccgatc
    44821 cataatccca gacattggta ccgagggtgt tcccgttgaa gaggagaatg ccctcgggtc
    44881 cattaccgga ggggacgaag gtgatgaggc tcgcggatgc cacgttcgcc gggttaatgg
    44941 ataatccgga gaacgggacg taggcagtcg cctcttccgg cgtggtcgcg tagttattct
    45001 catccgcgcc gaggaggtcg aactcctcgt tcatgaagat ctggcgccgc ggttcatcgg
    45061 ccttctcgta caccaccgcg agggtaagac cgtacatggc aaggttgctt gtctccgcat
    45121 ccttgtggat gacgacgctg ttgcccccgg tggtgaagta tggcgtcaca tcgtaagcga
    45181 ggagcccgta gacgtggttc gcgtacccgc cgaagttgct cttgtcagta tataaagtat
    45241 cgtccggtag aaggtgcccg ttgaaggtgg cgctgaaccg gtcggggacc tcgttcgtgt
    45301 tgtcccatgt ataaggcacg tagagccgtg cttcccggat tgttgcgcct gaggggactg
    45361 gcagatcggc tgcagtccat gtcaccgtat aatcgttcca tgcactggcg ccgacacctc
    45421 ccgaccggta ggtactgtcc ccgggcgagt agagcaggtt gccgtgcagg tcgaaggtct
    45481 tcttcgtcgt gacatcgctt gccccggccc agaagcgctt gcccttgtac ccattgtagg
    45541 cgaccgtgta ggtgttggcc acgacattat tgccctcgtt tgattcagtg accgtgttgg
    45601 acggatcgac cgtaccggta taagttaggg aaccaccggc gatgtcgcga acggtcgtat
    45661 ccagtataga aaccacggtc tccgcattgc tggcaagggc cggaacactg gcagagcctg
    45721 agaaaccatc gttcgagatg aggttcaccg tggttgccgg agattccaca ccaccgatgt
    45781 tcttcactgt aattttcact gtgttggtct ccttcgcaaa cggcgtgttc gtgaccggcc
    45841 ggaggtcggt aatggtcagg tctgggtttg cgggagccga aacggtgatg tacccggctg
    45901 gtgaggtatt tgtatttcct ccgggtaaca cagggttcgt tacagtgagc cggatcctat
    45961 aactgcccac tgatataaag gtgtagaagg ggtgctgttc agtcgaaaac tgagtccagc
    46021 tccctgaacc aagccggtac tcccatttcc acgtcgtcgg cgggccggtg gagaggtctg
    46081 tgaactggac atttagaggt gtagttcccg aaaggggggt ggcgctgaaa tcggcgacgg
    46141 gggagacgta gctgggtgct tttttcacgg caagcacagc tagcgggatc ttgtagaact
    46201 gatcggttaa gttataggta aggtcgtaga tatccccgaa agtcgttgca gaggtcacgt
    46261 cccagatatt gtacccgaaa tacgacccct gaaaattccc ggttgctgga tccgaatcaa
    46321 taggatctcc cccccatgcg tatgtcccgt ctgaactcgc catgtggttc acggtgagcg
    46381 tcgcggactg gacggtgccg gaaaggctgg acaggtcgaa gttggtcgaa cctatatacc
    46441 ccgtggtatc gtagtacgtg tccgtgtcgt gcccctggtt tacccagtag tagatggtgt
    46501 ctgtgtctcc gtcattgtag gccacgacga gggtgatcac cttgatccgg ccatcgaagc
    46561 tcccgtcgag ggccgaagtg acgacgtggg ccttcggggt ctgcgaggtg atgagcgacg
    46621 tcacatcgta ccacatcagg taatcgctcg tcacccggtt catgtggtca ttgaccttga
    46681 ctggtccgct tcccccgtca tggggaaacg tgtagggcac gttcatcgtc tcggtgccga
    46741 gcgccgtctc ataagtaccg tcaccatcgc cgtcaaagct gatcgcagcg gtgccctggt
    46801 agttgttctg catatgcccg caatagacag acacgtacag ccgggcccaa tcgatgtcat
    46861 tcacgttcgg tatcgtcgca aaggttttct ccacgtcttg gacaccgggg tcggaaggcc
    46921 accagtcgtt gttcgcatcc acgtagaccc cgccggagac cgtcccgctc tgtaccgtct
    46981 cgagcgggat gtccccaaca tacgggtccg cggccgccac tcccgcgagg cacaggagca
    47041 gcaggagggc cagaaatggc ccccatttct gttttttcgc cagtcgtttc ataagttatc
    47101 ccctattttt ccttgactga gagggttctt ttcaccctga aaagagaaca tgctccggat
    47161 gcctgcagcc attcgttcgt catcccgtct ccccgggaaa aagaagggag gatgatagtt
    47221 ccggtgtcgg tagactgctt tcattatcct ttcatctctc tccttccttc cccatcctga
    47281 tcagcaggaa gagggcacag gcgatcccca tgattgctat caccccctcg aacccgggca
    47341 ggaaaccctt gctcggggcg acggtggttg cctgggttgg ggggcttccg gcctggagtg
    47401 tcaccttctt ctcggcgaga actttgccgt cctgcatctc cacccgtgca acgacctggt
    47461 aatttccctt cgggaggccg tttgcaaccg gtgcggtgaa cgtgaccgac tgccccggca
    47521 cgatcgcccg gacgaacggt tctgatttca ccgaggcgat aaccctcccc tgtgcatcgg
    47581 tgatggtcac gttgtgcacc acaccgtaga aatggtagtt cccggagttc cggaacgttg
    47641 tggtcactgc aaagggtttt ccgacttcgg ccacaggcgg ctccaccgcg gtgatctcac
    47701 cggtctccct gaccgttccc gccttcacgg tgaggaagac cgggatggcc accgccgttg
    47761 cgaacgcggc aggcgcaccg gaggcagagg gtgctggatg gaccaggatg atcgcgtagc
    47821 gtcccccgtc ttttgcatct gcaggtaccg atatggttgc caccaccatg gcatgttctc
    47881 ccggcttcag gctcaccacc ggtttatcga cggtaatgaa tgggcgtgcc gagtaggtgc
    47941 tcgtatcgcg gcctgcctcg agggccacat agctcccgtc cgcgggtgcc tgcccaaatc
    48001 ccagcacttc aatcgcatag tcgccgcccg cctcattctc gccgatggag attcctatcg
    48061 gggaagtata gatcttccct ggctcgacgt cgagcgcgat gcgtgcaccc tccaccttga
    48121 gggcgaggac tggcgacacg agtaaggctc cggcgatgag gagcgcgagc gtgatcagac
    48181 agatgtgggt aggggtgttc cggttcatag gggaatcatt gctccggtcg atagcatcct
    48241 gtagcggttt tcccggggat acccggaaaa aggtggttgg gaagatcgcc tcatcggtcc
    48301 cttcaggcca tggagccggt gaaggtcagc gtgatgctgt agcttcccgg tgcatcggaa
    48361 gccgcgattg cctgtttcac gaaggcggtg ccgctgccgt cagccccggc cgctccggtc
    48421 aggaagtccg cgaacggcga ggtcatggcc tggaagttcg ttccatcttt cgagagctgg
    48481 aacgggttcg cgaggttcac cgtgccggtg cccatgtacc cgccattgct cgcggatgcg
    48541 gagaccgacc aggccgtgcc gcccgtgacg tccacgctca ccgtgctgct gccggtctcg
    48601 tcaacaccgg cctgcatggt gccgaagtcg atggatccgg gagacatggt cacgtttata
    48661 gaggactcac cgacggagat gatgttcaac ttcgtctcgg tgtcagagta gtccgggccg
    48721 gttgccgtga cgcggacaga ccaggtgcca ttactgaagg tgaacgatgc atcctctgtg
    48781 gtcgcaaact gggtccaggt cgtgccgtca gcgctgtact cccacttcca ggaggtcacc
    48841 gcgccgccgg tgttcgtggc gtcaaaggcc accgtgagcg gttcaacgcc gcttgccggg
    48901 gagaacgtga agtcgacatc cggtgccggg gtcttaacgg tgaccatgtc ggtcttggtc
    48961 atcgtgtcag agctgctgat accggtgatg gtcagcttca ctgaatagac gccgggtgta
    49021 gagtaggtgt aggtcggact ggcagccgtg ctgtccgtgt cgccgtcatt gtcaaagtcc
    49081 catgcatagc cgacgacgtt accagtggtc gtggcagcga aggtcacgtc cagcggtgca
    49141 tcacccgagg tcgggcttgc gctgaagtcg gtgatatcga ccgcaccctc ggtcttctcg
    49201 acgacgagga tcaggttttg tgcctgcatc aggtcgccgt ccgtggcgtc gcggctctgg
    49261 agctttgccg tgttcgcacc gctgacgagg ttcgtcaggg tgaactcctt gatggagact
    49321 gtttgtgtag tgctcttcgt ggcatcgatg tagaagtcat cgtagtccgc gtcgttgaag
    49381 ataaactggc tctgcccgtc ctcgttcacc gcggcgacaa aggcaatggc ctttgcgctg
    49441 gccattccgg tgatatcaac gccattgaag agcgcatagg cggttgcctc ggcatcattg
    49501 gtgttgtagt tagctctcga gtagagcagg tcacactcgt cgttgatgta gatcgtcttc
    49561 tcggtttggg tggcagggtc ctcgaagacc acgaccatat aggtcgggta cagtgcgacg
    49621 ttcaggttcg atcctgaaga caggctccag gtgttggtac ctgccttgtt gaaggtactc
    49681 gtaacatcat acattacgag ttctgacggg tagttgtagc caccgtagcc cttccggtca
    49741 gtgtaggttg ccgtcggggt gacagtcgcg ctgttgaagg ttgccgtcca gagggcgctt
    49801 gccccggtcg tctggtccca gttggtggac tggtacagcc gggcagagac gatggtggca
    49861 ctgctcggga tgatcagatc agccgagctc ggccctgcgg tgaagcttgc ggagtagctc
    49921 atccagttcg cagactggta tgctgcgttc ccggtcgagt acaccacacc gatacgtccc
    49981 gtgtaggtat tcacggtcgt gaagtcattg cctgcagtgt accgcttgcc cttgtagccg
    50041 ttgtagtaga cgttcgagga ggtggtgagc gcgttattgg tctcgtcaga ttccgcgatt
    50101 gcggatccgg agtcagcggt aatgacaatc gagatcgcac cggtggtggt aggagtgtac
    50161 gtaaagtcca cgttggtggt tgcacccgct ccaaggcctg gcacgctgac ggtctgcgtg
    50221 taggcaccga tgacgatgct gacatcaaag gcacccgccg cgagcccgcc gttgtttttc
    50281 acggcagccc ggagggtgtt cggctcattg gcgctgataa cgtcatggcc gcttgccgag
    50341 ccggggttga tcgtgagccc tgtcacggtc aggtcttcat ccacgacgct gccgctgacc
    50401 gtgaggtcag cggccgatac ggctcccgga attaccagaa gcaggaacag ggcaagaatg
    50461 cccagcattg taagagtttt cataacagta ctccatccgc gggtggcgtg ccgcaggaat
    50521 acctctacct acaacgctta ttcaaataaa tattatgatc taatttaatc ttcgtagcat
    50581 attgtttgtt ttaaaaaatt atagttatga attaccttgt ttgtttccgg aattattaaa
    50641 aaaccagaaa agacgtaaat ttttaattaa aacttcttga ttaaaaaata agatattctg
    50701 cagaggaata acctggatta atttccgaat ttgcattcca tttaatcctt tcatggaaaa
    50761 agtattgatc ctaaaatttt cattctttgt aaacatgatt tgaaccttag tcacatattt
    50821 actgtaaatt tatattctga ataaaaaaaa tagcattgaa atcacaatat taatacaatt
    50881 tcaccgttag tatctcagca tgcacaccgc ccgttctgca atcaccgcct gcattgtcct
    50941 cagtctcatt gtgtttgcga caccctgcac cgccctctac gatttcgagg gcctcgcctt
    51001 tcgccccgca gccatgggag aggttgacgg gaggcttgtc actgccggaa cgttcggact
    51061 ggttaatccc ccgatggaat gcacgatcac gcttgatcgt gcccctgtat gggcaaggat
    51121 gtactgcggc gtctggggcg ggaccgagcg gtacaccgga tgggtccggt tcacggtcaa
    51181 cgggaggcct atggagcaga tcaccctcta tggccaggac gaccgtaccg aggggatcta
    51241 ttgcagcggt cacggtgtat actggatcgc ccgggacgcg acctctctcc tgtcgcccgg
    51301 gcagaatacc atcagcgtct cgacgagcaa gggggagagc gggagcagga tcgacggccg
    51361 cgtctacgcg gtgatggtgg tcgcggcggt agaggatacc acaggaattg caacacggta
    51421 tatcatcatg gaggggaacg agaacctcca tggcgagggg tggtcaggca cgaaccccac
    51481 gcggaaggac cgggtggagg tacccatcgg cggcatgccg acgggcagcg tgaagaaagc
    51541 ggacctctcc gtcttcctgg cggcaaccaa ccgcgggcag cctgactatg tcctcttcaa
    51601 cggggcagac atgggtgtgg tgcccgcaaa gggaacctac ctgcccgggg caaaggatat
    51661 cgggaacgag cagtcctttg atgcagccgg gggagaagga atcgagagcc ggtacgtgga
    51721 catggagtcg ttcgatgtca ccgggcatct ccgggcggag aacctgctgg tctttgaacg
    51781 cggtcgtgac ctcgacgggg atggcaatat cacgacgaca ggggcaacac ccgagggaga
    51841 ggactatgtc cacccctgcc tcgtaatact cgcggcagaa cgggagggac aggcatcgtc
    51901 ccctgccctc tctgtcgagc ccttcgagat aaataatgcg tatgccgggg agagagcaga
    51961 ggtaaaagcc gtggtatgga acacgggccg ggcactcaaa gtcccggtga cagtgtccct
    52021 cctcgtggac gggacgcgtg tgggaagcac tgaagtcacc ctttcccctg ccggcagggc
    52081 ggatgtctcc cttccatggg atgcagccgg gggaacacac ctcgtcagtg ttgaagcaac
    52141 tgcacccggc gcaacgccgg ggaaggccga aaaaagcatg aaagtcggga ctcccgtcga
    52201 tcttgtcgtc tcggtgggac cgcccgagcg ccaggacggg ccggggagtt cccccatggc
    52261 cacgacaccc ttccctatcg ccgcgcttgc cgggggatcg gcaatcgggc tgtggctttg
    52321 ctcgcgccgt tccggtctcc ttcctctcat cgtgacagtt gctgctgtat cctccctcct
    52381 ggtcatcccc tttgtccatg cgtcacctgc cgcgggaacc tcctttactg cgtactcgct
    52441 ccccgtcgag atcaggaaca cgggggggag tgatgcccct gcgttccctg taacggtcat
    52501 ccttgacggg gaaaaggtca caagaatctc ggtacccggt gtgcctgccg ggggattcgt
    52561 acgtcaggac attgcagttt acaccacccc ggggcgtcat acagtttccg taatcgctga
    52621 cgaggaaggg actgttgcgg agcggaacag gaccaacaac cgggcagatg caacgtatga
    52681 cttcccgtaa cgcctacctg ctctttgctg ccggcacgtg catcctcttc tgcacagccg
    52741 ctgcaggggc gagttacgcg ggggacaggc ccctcgcgct cgcctacagg ggtaccgttt
    52801 caggcggcta taccttctcg gaaggcgacg gcggctacag cggcactctc aacccgggac
    52861 agacctatac cgcttccttt acccgggaga tacccggagg tgccgtcacc cggttcgagc
    52921 gcctttacgt ctactggacg tggagccgga tcgaccagtc cgcgtcgtat ccgaacatgg
    52981 aagtccgtct cggcgggccg gaaggacccc ttctcgtact ttcggcccgg tacactgaca
    53041 gcaagggatt tgcgagcaag aacgactttt tctctggcct ggacagctac ctcgtgcctg
    53101 ccacaggagg ggaaaatttc tctgtataca tctccaacac agcaaaagac ggcagtacct
    53161 ttgccatcca gggaacttcc gtcctttcgg tctacgaggt gacggccggg cgggagaccg
    53221 ccatctgggt tgcggaggga gccgaccttc tttaccggag ttatggtatc ccgcccgagc
    53281 ttgcaacaac gagggtggac tttcccggga gagtcgatat cccccgcgtg gaatcagcac
    53341 gcctcttcct cgttgctccc tcggctggtt tttcccgtga agaagtcccg gaaatgaacc
    53401 aggtcatgat gaacacgccg ggacgggggc agctcccgcc gctggtggaa ccggtgttga
    53461 aggtactctt cccccattac aggggccgtg catggagtga tgccttttcg gcagacgagg
    53521 accaccagat aggaatcgcc caggcagagg tcaagccgtt cctccggtac tctgacaact
    53581 ttatcgaagt gagggacaac ggggactacc tgatgctctg caacgcagtc ctttccgtaa
    53641 cctaccagga gaagagagaa tgagtccgcc gatggtcgag acgcggcagc tcacccgttc
    53701 gtaccccggt ggcgtcgagg ccctccgggg agttgatatc accgtcggga ccggtgagtt
    53761 cgtggccata gtgggccgga gcgggagcgg caagagtacg ctcctcaata ttctcggggg
    53821 catcgacgcc ccgacggggg gctttgtttc catccgggga aaaatgctgg actacacgaa
    53881 ccggaaggca ctcatcgcac acaggaggac gacagtgggc ttcgtcttcc agcagttcaa
    53941 cctcattccc tctctcacgg cccgtgaaaa cgtggaatac cccctcctct tttcgtaccg
    54001 gccggcatca gagaggcgga agaaggcaga agttctcctt gccacggtcg gccttgcggg
    54061 ccgggcctcc cactatccgg gccagctctc gggaggcgag cagcagaggg tcgccatcgc
    54121 ccgtgccctc gtgtcagacg cccccctcat tctcgccgat gaaccgaccg gaaacctcga
    54181 ttcggcaacg agcggagaaa ttttttccct cctgcggagt ttgaacaaag aaaagggggt
    54241 tactctcatc gtggtgaccc acgaacggga actcgctgat tatgcggaca gaacgatcgg
    54301 gatgaaagac ggccgggtgg tcgcatgacc atccgtctcc tggaattcat cgagctcgca
    54361 ttccgccagc tcttccggag gaaggtacgt gtcatcctga ccgtggccgg gatagccata
    54421 ggggtcgctg ccctcgtggg gacagtctca ctcggagagg gtatacgtac ccaggccgtc
    54481 gaagccatcc ggacgcagtc agacttaacg ctgattgagg cactccccgc ggtcgaggga
    54541 aacactctcc agctggtcac tgcaacgaaa gcgtctgccg caggatctct ccccgggatc
    54601 aaggcctctg cccctctcgt caggagcacg tttgcaacgc ggggacagac atacgtgcag
    54661 gtcgtggggc tgcccgcggg atcgctcgat gacgtgctca tttcccgttt ccagaaaggg
    54721 agaggtttta ccgccggttc gaacgaggtc gttctcgggg catcccttgg gcagaagctc
    54781 cagcggtacg agggtgcccg catcggggat ccgctcgttc tcatcaggag gacgtacgat
    54841 accgcgggac gccccgtgga caatgagaca cgcgtcgtcc cggtcgggat catggaggaa
    54901 aggggcgacg atttcgacca gatactcctg atggacctct cttttgccct ctccctcggg
    54961 gctgatgaag ggggatacag cggagtcctt cttcggacta ccggccccga ccaggtcttt
    55021 cctgtcgcgg gtggcatcag ggcactcggg ctctctcccc gtggctcttt tgaacagatc
    55081 gaggctgtga acaggatgat ggacatggtg gtaatcttcc ttgggatatt cgccgggctc
    55141 tccctcctgg tcggtggtct catgattgca agcaccatga taacatctgt atatgagagg
    55201 acgagggaga tcgggattgc gatggccgtc ggggcatcgg aaggagacgt catggagatg
    55261 atccttaccg agtgcgcagt cctcggatgc attggcggga tttgcggaga tctgctcggg
    55321 atcttatttg catttatcct caacaccctc gggggaccgt tcctcgcctc ccgcttcggc
    55381 gatgcatttg caggtcttct ggactccgag attgcgctgg taacctggcc tctccttgca
    55441 ggcggcctcg ccctcgcaat cgggctctcc ctcgttgctg gtctttaccc ggcgtggaag
    55501 gcgtcccgtc tcaaccccgt ggaagcgata cggtcaggaa ggtagaaaaa tggagaggaa
    55561 agagttattc cgggcactgg tcctggtcct ctggatcgtt accgtggtga gcatccctac
    55621 gggtgcagac ccttacctgg ggggtatccc gctcgagacg gtcagggaag gaaccgtttc
    55681 cggcggcatt tttgtcgatg ctgcgtatcc catgtcaacc gacgggagtg cgaccttcgt
    55741 gctgccggct catactggca tccagtgggc ccgcctctac gtcgttgtct actgcggtca
    55801 catgcagaac aactaccaga cccgggccga catcgagttc aacggtgggc aggggataac
    55861 aaaactggcg acagaaatac tgaacgttcc ctattcattt cccggggagg gaggttcggg
    55921 ccccgtccgc cttagtgacc atggtaaccg cgtgacgagt gactacctga tgtggtatga
    55981 cgtcaaggac cgcatccagg gcagtaacgt gcttgtaagg gtaaagacat cgcgtccgca
    56041 gggttatacc ggcacgttcg acggcaggat caaggccatt gttctcgtgg ctgcatacga
    56101 agacggtgac caggacaagg ttttctactg ggtcaaccag ggtcacgacg aagatagcga
    56161 actgaccgaa gagatgctcg gggaaaccta tgtcggggaa acgacctttg gaacgggtat
    56221 gctcacggag gactgggaca aggctgagct caatgttgtt tacctggcaa gcaggaacgc
    56281 ggagtacgat ttcaacgggg atccccttcc agccgggaaa ccgcagggtc cctacgcagg
    56341 tctcgacagg tatgacgtaa ccgacagtat ccgcaagaaa agggactcgg acctctccta
    56401 cgataacata gagaggtatt tcaagatcat ccttgccacc ctggcagtcc ggtttccggg
    56461 gagcgagaca gggaacctgt cggtaacatc gagcccgccg ggtgcaaaag tctccatcga
    56521 taacgaagaa caggtgcagc gcaccaatgc aactttttcc ggtatcccgg cgggaaacca
    56581 tgtcgtcatg gtggaaatac cgggtttcag ggttccggct ccccagactg tcctcgtcca
    56641 gacaggtgag accacgagca tccacttcat cctctaccag ggtaaaggaa acatcacggt
    56701 cgagacgaac ccgccgggag ccgaggtatt cattgatggg gtgaaacatc cggccctaac
    56761 tccctgcatt atcggtgata tacctgccgg cgagagagaa gttgtgatcc ggcttaccgg
    56821 gtaccgggaa tggagagaga ttgccaggct ctccgacggg gagacgctgt ccctgcaggc
    56881 aggactcttt cccgccgggg acggagggtt ttcaaccggg gaagtaccgc ccgccaccgt
    56941 gcaggctccc tcgggatacc gcgggtccgg gctcactctt tataaacaag ggaccctccg
    57001 gggaacactc ttctcggcct gtgcgggtga ttacaccgga atgattcctg cggggcagga
    57061 gaggactttt atcctcccca attccctgcc cggcgaaggt gagatcgttc tctcccgcct
    57121 ttacctctat acaacatgga gccacgatac gacgaaaagg gaaggggtcc ccgcagtccc
    57181 gacggttttc tggaatggac aggagttgag gctggatgct atctatgccg accggaaggg
    57241 agatggtatc tatgactatc ctgtccagac atttgcttac gacggaaagg gagtcataaa
    57301 gacaggagaa aaaggcacgg ttactgtcag gaacagcgga gagacaggca gggaatttgc
    57361 cacttacggg gtcctcctcg ttgcacttgt ggaaaatcca gaagacccgg agatatccta
    57421 ctggatctgc gagggttctg atatcgtctt tcccgatccc cggttcggga caagtgcaca
    57481 ggaagcccgc acgagggtca cgttccccgg ggatatagaa atttcgggaa ttgatagtgc
    57541 ccgcctcttc attgtaagta ctgcggcatc cggagaaggg aaagaccaga atatcgtcat
    57601 attcaacggt ggtgagtggt acaatctcct caatgcgggc tcttccggga tcagcatggc
    57661 agacctggac gtccgttcct atctcttaaa gggagataac atacttgaaa ttgcgagctt
    57721 ttccgctgaa ggaggggggg attacatgga gaacaggaat gcggttctcg tcctcacgca
    57781 tgcggatggt ggggaaagac aaacaaacca gggggaggga acagacaagg gagaggtcag
    57841 gcccgggacc ggggaaactt ctctccctcc gggtggtctt gcaaccggaa catcacccac
    57901 tggatgggaa ccccgcagtt ttctcgatag tgctatcgag tggatatttg cacatatttt
    57961 caaggtttta ggtctttctc ctctccctgc aggagaagat tatccaatac cacaccccgc
    58021 gtccaaaacc ccggcttttg acgatctgca aagacccgtt ccccaagaac aggaggagga
    58081 gaccggaaaa gcgaaatcgg gggaaacgat gttcctttcc ggcaacccga caggagatgc
    58141 ggaaacgctc cccacacccg ttatgacgga aagcaccctt atgccgacgg gaaccaacga
    58201 tacactttca cctgaaaagc cggtaacggg aggtatcttt gtaacctcct atccaggtgg
    58261 tgcagcagtc ttcatcgatg gcaggaaagt cctgtccaaa acccctctgg ttgccaactg
    58321 gctcaaggca ggactccata ctgtccgggt ggatcaggag gaggcagaat ttacccctga
    58381 ttcccgtcag gtctgggtgg agccgggcga aattacccct gtgtccttta ccaccggtgg
    58441 agcgtatttt aggaccctga ccatcgagtc aagggaattt gaggccgcat ctttcacagt
    58501 gaatggcagg gggccggtcc ttgtactccc cgcgaaagta actctggaag gtcattcccc
    58561 gtacgtttcg gtcatggtag acggggaatt gtattcccag acaatcccgc cccggataca
    58621 ggatgggtct tctttcatct tcacgcggga aggaggagct gctgcatcag tgaaggtcac
    58681 ctcaacgccg ccccgtgcca tcattagcat cgacgggttt ccgacgaaga aggtcacacc
    58741 cgctaccata gggaatctct cccccgggca gcatcggatt gttgtttcct gtcccggtta
    58801 ttttcccgcc gaaagactcg tgactctcgt tgacttcgcc agtgaaccta ttgacatgtc
    58861 ggttgatctc tcccttgaac catatcagtg ggggaacctg acggtggaga gcgatccccc
    58921 gggtgcacgg atttacctgt ttgggaaaga taccgggaga aaaactccgg ccactttcaa
    58981 ttatctccag atagggtcaa ttcagggaaa gattcgctgg gacgattccg agaaagattt
    59041 cgaggcagaa gtgctccctg agagggatgt tggtattctt gtgaggcaaa ccagaagaga
    59101 ataaatttta taaaatttaa aaccacgaaa ggaaaaatcc aattatcctg aagcaaagat
    59161 gttcgctggt tggttatttg gatttatgaa aatccaggcc ggggaaaaaa ctttgctatg
    59221 aaattgattc cctttatcgc gacaaggctt gccgcaattc tcccttcaat tcgcatatta
    59281 aatccctttc tgacagaccc gcgcctgtgc ctatgacggc atgaacgatc ccgaccgccc
    59341 tggggatggc attccggact ggatcagaca aaccgtactc gactaccggg tatgacactc
    59401 tctggggctg gcaaccgatg atgagtatgt caatgccatc cttgatccga tcgaagggtg
    59461 acgcgatgtc ccacgagaag gggtcacagt aagagcccgc gggcaggtca tcgaccccga
    59521 aaaaaccaat ggaccagaaa attatggtgg cggtaatcga acaaaatgat aagagattgg
    59581 ggggacgaaa atccccccgg ggacgggcag ttggactgtg ctggttggtg gaccggtcaa
    59641 aactctt
//
LOCUS       DAOOJU010000008        59130 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_604_length_59130_cov_15.167973, whole genome shotgun sequence.
ACCESSION   DAOOJU010000008 DAOOJU010000000
VERSION     DAOOJU010000008.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 59130)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 59130)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59130
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_604_length_59130_cov_15.167973"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(64..1536)
                     /locus_tag="PK679_03400"
     CDS             complement(64..1536)
                     /locus_tag="PK679_03400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HPC55035.1"
                     /translation="MKRLETLAIIAHDMGAIFEFLGLITLLPFLVVVVFGEWDMFLPM
                     VSVPLTFGLLGLLISHIPRKEYVPQLSVALTAVALIWVAVALIGSFPFVLGMHMSWTD
                     SIFESMSGWTGTGFSVIDNLDTTPKTLLFWRSFMQWLGGIGVIAFGIAMLSRSGLTQH
                     QLYRAEGRSEDLMPNVVSTGRRMWVIYVFLTVVFTGMVMFAGIPLWDALNLVMVSLAT
                     GGFSLHNAGVSYYDNALLEILLIPVMLAGALPFKLYFLIYRGKIRPFLQDRVVWLILF
                     LALAGSLIVTIDLHLFNGLPLETAVRQGFFCTVSGLTCCGLQNSNLQWIASPLIIISL
                     LMMIGGAAGSTSGGIKANRVILGYEGLVWWFRRFFSRGRVIVPFRHEGRAIPRRISDV
                     ELSKNMLIIVLYVLTIFLATVISLHLAPTGFRTHQVIFEEISAMSNVGLGLGYLTPAS
                     PLPIKWVFIFLMWTGRLEIIPVLILAMGLIRGFEPRIKGK"
     gene            2194..2276
                     /locus_tag="PK679_03405"
     tRNA            2194..2276
                     /locus_tag="PK679_03405"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2228..2230,aa:Leu,seq:tag)
     gene            complement(2473..3177)
                     /locus_tag="PK679_03410"
     CDS             complement(2473..3177)
                     /locus_tag="PK679_03410"
                     /inference="COORDINATES: protein motif:HMM:NF014845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HPC55036.1"
                     /translation="MKAIDSPLKGQILEMLEAGEMDFEEIVTRTGKAKSTISVHLKAL
                     SEAGITVSRPDPSDARRRLFSLNGRILIRTLALDRDMKWADNFFPDRLPPDATTRDVF
                     SFILTALRVSLISDGIEIHPILSQAGRRAGKAIYHLVEDDDTLSFFSRISCFWEKFGL
                     GKMELERDDPFTIVIRDCFECMDLPLTGKPECSFGGGVLSALFSAHHGEAREAIEKNC
                     YATGSNLCRFEIWNAR"
     gene            3464..3736
                     /locus_tag="PK679_03415"
     CDS             3464..3736
                     /locus_tag="PK679_03415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55037.1"
                     /translation="MTLVSTPTQTDGIEVRRQVTTIDCLPSSARAVYMLLSDGKERTL
                     NEIIGRVAFSPRTIRNALSRLRESGLIIAKFNFRDARKPLYRLKTA"
     gene            complement(3928..4779)
                     /locus_tag="PK679_03420"
     CDS             complement(3928..4779)
                     /locus_tag="PK679_03420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005384 - manganese ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030026 - cellular manganese ion
                     homeostasis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="HPC55038.1"
                     /translation="MEAARSFQKDEVTEYHIYQRLAGMMRDERNASVLQKMAREELAH
                     SRFWQKIAEVEEGPDTIRVWWYVILAKLLGVTFAIKLMERGEGSTIRTYRAVSDRVPG
                     IEEVIWDEEQHENSIIAMISEEKLRYVGSIVLGLNDALVEFTGSLAGFTFALQDSLVI
                     AAVGSIMGIAAALSMAASEYLSRKSDRSSLDPIRAALYTGAAYIFTVLVLVLPFIMTA
                     NPFLAFLMTLICAILIITGFTGYTSVTLDLPFGRRFAEMAALSLGIAAVSFLIGVFIR
                     VFFNVEV"
     gene            5029..5625
                     /locus_tag="PK679_03425"
     CDS             5029..5625
                     /locus_tag="PK679_03425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55039.1"
                     /translation="MKKVLITLKKDDAPNITQLLGGAYSYREEIDDRVRFTLVVPDTK
                     LDDLVSRIRTVLDFVDKETLVEVYSPDFTIFPAFDEKKKQEEGSREKKKEKSPIEKLL
                     ASVESYEKLDTKILTLAGVASIVGLIGLFLNNVGIIIGAMLIAPMIGPIYSFASILRP
                     GTVSVLPGISSTSSPFSSHSSCSPSQSRGSSVFSSPWK"
     gene            5571..6005
                     /locus_tag="PK679_03430"
     CDS             5571..6005
                     /locus_tag="PK679_03430"
                     /inference="COORDINATES: protein motif:HMM:NF016013.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF389 domain-containing protein"
                     /protein_id="HPC55040.1"
                     /translation="MFSLAVTWIIGFFVPLEVTGEILARTHQSPVYAIMAIFLGFATI
                     VALAKGIPDTIAGVAVAAALLPPALVSGLSIVLYPGGTISAVILTLQNVIGLMAGAII
                     ATIALQIRPRSYKETQAARTILIRIATLLLILILLLLLIPLF"
     gene            complement(6035..7150)
                     /locus_tag="PK679_03435"
     CDS             complement(6035..7150)
                     /locus_tag="PK679_03435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC55041.1"
                     /translation="MRGVIRKRREFLKLMRACTVDRGYFTVTDIQKQAGVPRSTAQDW
                     INRLLDEGCVVLKERKLGRNPAKYAAISALPSSACRRIFTTVDGDRVEIYHECMSNAC
                     AAFCAYHHSRAGGVLEDVMRDGPLLRERAHLGQSRIEIGLHPASAVGVAGVEREGNDI
                     IQHIRCIGGPAYSLTDMMAKAEGVCDVKIQKSGGLVEGSVRTRALVHLVIGLDDTDSR
                     EGGATFAMALALLQHLETLKGVLPISHHIVMLNTAIPEKTTGNSCSYIEIAIPPERYE
                     DVRNRALVFIQDESLSPEWGMAFRRGFSIPGIFRTFGSKARSGVVDEKEAEAVAAKNG
                     VELFGGRGRIGALAAIALSGLPHEILLRPFAPIPPGS"
     gene            complement(7122..8120)
                     /locus_tag="PK679_03440"
     CDS             complement(7122..8120)
                     /locus_tag="PK679_03440"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HPC55042.1"
                     /translation="MKVAILGMGSVGKGLMQVISERDLGLVVTAVADSRSAIMDRDGI
                     SIDEVLEAKRLRGYCGDTSLSAMDVVTKGTYDVLVEVTPTNALTGEPGLSHILAALDR
                     GRHVVTSNKGPIAREYERLRRCAAEKGVLLRYEATVGGAIPIIHTLEQGLAGNRVLAI
                     FGVLNGTCNYILCRMAAEGLSYEQALLEAREMGYAEADPTYDVKGIDPAIKLVILANT
                     FWKKPVQLEDVEVTGIDMLTNDALRLAEEQDCTIRLIAEAIPDRGILRVAPRLLPLSH
                     PLVVDGTLNAITIETDLAGEITLIGKGAGSVETASAIIGDLLYIRDFHEGRHKKTP"
     gene            complement(8117..8611)
                     /locus_tag="PK679_03445"
     CDS             complement(8117..8611)
                     /locus_tag="PK679_03445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HPC55043.1"
                     /translation="MKLEMRDAPGQLVAALRPISEVGGNIIAVIHQRDEKATKGDTLS
                     VQIVLELPDQRLSDLVRLIREQGVNIQRIGHERLLYEKTVIVIGHLIHTDLGDTVDRI
                     DRTGFAEVTGLNICMPAITQVSSARLVVKAVNRQDMEQAMDILRGVSKEKNFLLVEPL
                     EEIE"
     gene            complement(8713..10041)
                     /locus_tag="PK679_03450"
     CDS             complement(8713..10041)
                     /locus_tag="PK679_03450"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HPC55044.1"
                     /translation="MGTLTRAIPSLLEKRSFWIAVLILSTLFAFFLNYYGMQRGLLSI
                     TSHLFYIPIVIAAYWFTRNGVTLTVVIAMGYMAMVYFFRYPEVESLAQATAYFYVFVA
                     IGLIVGSLSGTQKEQEKRYHGIFDYSEAGVFLVINLRSGPVIEEVNYRGAQLLGYRAG
                     ELAGTPFLDLFAVGPEKERVMESISRGGTVTDFECHLRRKDGYILHGLLSAGPVPGRR
                     TVLTLVDITAIKKAEEELRASQSQYVNALNAMMDGILLVDRDFRIVLLNSTLRRWLSH
                     IGKEGNVIGMEVGEAVPCISSQVSDTIRSVFETGKDGETILDFHFRGQDYFFEAHLIP
                     VIAAEEVTRVMIIMRDITRARHLEREKKRAYQQIEKNIEQFAILGDHIRNPVQVIMGL
                     ADLEGGPFAGKIREQVHEIEKTVAQLDRGWVESEKIREFIRKYYGIGDDT"
     gene            complement(10175..10747)
                     /locus_tag="PK679_03455"
     CDS             complement(10175..10747)
                     /locus_tag="PK679_03455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55045.1"
                     /translation="MTRRRLFLFVEGNDDERFFAKVIVPLFESRYRSVHIVKFACMKR
                     ASVCRLVTGIHRMKDDFLVFADIDNEPGVKAKKHLLMERFCVLDSREIIIIIREIESW
                     YLAGLDDAAERDLSLPHHSSTDDLSKEYFNSRIPRHFVSRIAFMLDILSRFSAPVACR
                     KNQSFHYFATRYHLVPCDTSADNRGESGGD"
     gene            complement(10744..11997)
                     /locus_tag="PK679_03460"
     CDS             complement(10744..11997)
                     /locus_tag="PK679_03460"
                     /inference="COORDINATES: protein motif:HMM:NF024700.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HPC55046.1"
                     /translation="MPIRKLTVRNFKSFSHLEVEPDNFTVVIGSNASGKSNFIQVIKF
                     LRDIAKYGLANAVSLQGGVEYLRNTLIGASEPFSFRIDYVLDERRSDIVALKSGSPVF
                     FRPGEISYTFSLSFHERGENYEIASDTLTVSGEFLRLEGQEKKETGIGTIRLAREGRV
                     IHYTITPPDGLELRNEELLPFSFRTTEADRKKLIMTVPLFIPGVPSLEWIFRGMKVYD
                     FDPRLLKRAVPIMGKTDLEKDGSNLAIVIKKIIDDPERRNLFSRLLHEVLPFVDDVEV
                     EKFMDMSMFLKLKEVYNREKYLPASMVSDGTINICAIIIALYFEERPVTIIEEPERNI
                     HPYLISKLVEMLKDASRNKQVIVTTHNPEMLKHVSIDDILLITRDRDGFSNVSRPANR
                     QEIREFLEQEIGIEDLFIQNLLGLE"
     gene            complement(12056..13537)
                     /locus_tag="PK679_03465"
     CDS             complement(12056..13537)
                     /locus_tag="PK679_03465"
                     /inference="COORDINATES: protein motif:HMM:NF024832.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HPC55047.1"
                     /translation="MSVPASLLRRLLGIEAVRRHALLSLLTSTGITAVGYLSTVYIAH
                     VAGAGVLGAYYLFLAYYSIAALVSDGGFGGAAVRKMSRDGQEGAFFTAQAVARLFLTG
                     LSIAGIILLAAPFMHDARSAGLLPWLVAALAIGSVSGILASGIYGHGSVGILQAGEFI
                     STVIRVTVQILAVGTGFAVAGMAGGFIAGLLAAVAINARFFRIRPAAFGLRHFRQLLP
                     DAAWGFSSSLAAVLALYADTVIVGYFLDPTGVGYYRTPLQLATLSLFVATSLSISLFP
                     RVSSWHGQGDTAAIRHALERALSYSLVLAVPVVCGGLVLGERLLYFLYGSPFIVATHA
                     FTLLLLAQVGAVIFVLDSMALSAVGKFKVVFLINALSCASLVLLEIIMVPSLGITGAA
                     AAVLIVSIFKACLSRLALFRFTGARAEIATIGHIAVAGLLMGGFVFILRWLFFPTHVA
                     VLAGIVLSGALFYFVILFRLERDLRKEIAELAEHLGVAGIPFP"
     gene            13661..14620
                     /locus_tag="PK679_03470"
     CDS             13661..14620
                     /locus_tag="PK679_03470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55048.1"
                     /translation="MQGSEETTEGERGDNRIRSPIIRARDLVKNYGNVRAVDTISFEV
                     MPGEVFGFLGPNGAGKTTTMRMIQCVSPPTAGFLSVFGLDVKDHPAGIKRWLGVVPQE
                     TNLDPDFSCRENLLVYARYFDIPAREAQKRADELLAFMQLTEKADVPIDGLSGGMKRR
                     LILARALINNPRLLILDEPTIGLDPQARHMMWEKLKALQAMGNTIILTTHYLEEAERL
                     CDRLVIMDAGRVLVEGRPADLVRRYTGDEIVESENSPQVLACLQEMGCRYEVHGDMVQ
                     AFSDQPRVLARRILETCNPGRVFVRRGTLEDVFLTLTGRELRE"
     gene            14635..15399
                     /locus_tag="PK679_03475"
     CDS             14635..15399
                     /locus_tag="PK679_03475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55049.1"
                     /translation="MPTWLAWKVWQRNRDVFFKTYLVNFLPPFVEPVLYLLALGYGLG
                     LFVGEIDGVPYVSFIAPALLAISMMNSSFFECTYSSFVRMYYQKAYDAMVATPLSIED
                     VIAGELLWGATRSLIYTTAMLVVLIAFGVVALPSSLLVIPFSFLAGLLFSGIAMCFTA
                     ISPSIDTLNYPAFLFITPMFLFSGTFFPLSVLPGPIQVFAMAILPLAQVVTVSRSFTL
                     ASVSLPLFLYSIAWIAVVCTVLFFVSIYLMRRRLVV"
     gene            15580..15852
                     /locus_tag="PK679_03480"
     CDS             15580..15852
                     /locus_tag="PK679_03480"
                     /inference="COORDINATES: protein motif:HMM:NF015069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family transporter"
                     /protein_id="HPC55050.1"
                     /translation="MDLWFIVGGIAAMLTTFGFVPQIHKMIRTRSVDDVSPLTFVQFM
                     AGVSLWALYGAHIGDVIVLLANIVTFGTLIVAVSLYFYLRPRKDGD"
     gene            15915..16961
                     /locus_tag="PK679_03485"
     CDS             15915..16961
                     /locus_tag="PK679_03485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55051.1"
                     /translation="MQGGREEDIRLSLIGYAIRAPSHRNSQPWKVALPGASRIVLSID
                     HSRVAGALDPSGRQAFLSCGAFLENLDIAARASGYRADIDLFPAGWPDPVKPLRDPVA
                     SIDLERDARIQPDPLFHAIPVRQTNRRPYSDRPVPLSVAGELGAAGDSELVPFGFTND
                     RNLIREIRDLVVDALARELSNRERFREYCDYFRFTDAEAAQSGDGYGFAQSGYGKITR
                     FFTGAFLFSRESVLRNPEAFRRRAVSDLGKIMEKCGGIGWLSTKGDFRIDQVRAGRAF
                     ERIHLRASSLSLALQPVASPVAGYGEMEEVRAGLSELLAIPGTHTIQVLFRTGYAKRV
                     PQTPRRNISDFIVS"
     gene            complement(16977..18239)
                     /locus_tag="PK679_03490"
     CDS             complement(16977..18239)
                     /locus_tag="PK679_03490"
                     /inference="COORDINATES: protein motif:HMM:NF014500.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HPC55052.1"
                     /translation="MSLLVLFLLVLLFLAFLSIYAKTPPFLSLLAGAIIFGMGAGMDF
                     GTVLGAVIAGLGRVFALFAIIIFSGAVIALTLREQGHLERMVADLRTGFPGSWSLAAI
                     AGYVFSLLTTCCITAFVILAPVIGRTGSDRHQKNMLLFLTAAGSVVSYTLVFPTPVII
                     PLLLGFGSGLSPLLYDLVAIPLSLALLAGLVLLFRKISGGKGGIAASSPAAGGSDVLS
                     SLRAWAPFIAIVVSIPLCLFVFSLSHESMIQAIMLAGLATALLLAPAEARSTGLKKGT
                     MHAGLIMFDICGAGALGNVILESGFAGAVFPAVSGTLPAVLIPFAFTAIIQAALGSRV
                     ATAVIASQVMAGTALASVLAPLPLILSVAAGVCIVSWLTDPFFWLLHRTTDATIREIS
                     LAYTLPLAACGAAVLFLALVLHSMPFPG"
     gene            complement(18268..18546)
                     /locus_tag="PK679_03495"
     CDS             complement(18268..18546)
                     /locus_tag="PK679_03495"
                     /inference="COORDINATES: protein motif:HMM:NF012911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HPC55053.1"
                     /translation="MKEIRVVVSGRVQGVGYRYFVRDAALRRNIRGWVKNNPDGTVSI
                     VAAGDSDTLEQFLEDIRAEGDPLIRIADISLTWSGEVTETWQGFEIRR"
     gene            complement(18635..19081)
                     /locus_tag="PK679_03500"
     CDS             complement(18635..19081)
                     /locus_tag="PK679_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC55054.1"
                     /translation="MAGTPGTGEDHEDEDSCMQCGLCCRVFGNGISPTPENIYSWIVD
                     GRTEILRHFRACRADGTWIRCTELDAPGTGSITAVEMRDPETGEYPTVCPFLRRVGKT
                     RYTCSIHADKPDMCRNYMPWVFGETYFPRCRALEKKGEVSPWSRIP"
     gene            19187..19657
                     /locus_tag="PK679_03505"
     CDS             19187..19657
                     /locus_tag="PK679_03505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55055.1"
                     /translation="MGFVCRQCGQCCMHMGDYIVIERQTGPFEFDACSVSTGTGFLAR
                     VDEDKRKLFLDREWIDRHPSACPFLRPGGALFFCCIHETSPAQCKAYRCVVFRIRSPD
                     GKPAGFITGTLALHTNDPALREAWKEVEEVMGKDPGLAEREIPAVLGRKGYMCD"
     gene            19851..20339
                     /locus_tag="PK679_03510"
     CDS             19851..20339
                     /locus_tag="PK679_03510"
                     /inference="COORDINATES: protein motif:HMM:NF015648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HPC55056.1"
                     /translation="MGSFSPTVPRNIRKHLAPGEGVVLVLHPSAWRYILHYLLGLILL
                     GFSIVLPVFEAKAVAAISGILYIAYTELRRRRIAYVVTTHRIMKEARLFSRRSSTLPM
                     NRITDVHLDQSFFGRLFNFGDLFINTAGEGGFELVMEKIPGPGDVKATIESQLLETRK
                     KS"
     gene            20444..20839
                     /locus_tag="PK679_03515"
     CDS             20444..20839
                     /locus_tag="PK679_03515"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HPC55057.1"
                     /translation="MDAIEEFFEKDLFARENGIELLHVGKGVAGVRMAIREKHLNSHG
                     TVHGGAIFSLADCAFALASNSHGVPAAAINAHISYMKAAKSGSLRAEAREFALNPRLA
                     TYTVEVTDDAGEKIAIFQGMAYRKTPPRG"
     gene            complement(21106..>21370)
                     /locus_tag="PK679_03520"
     CDS             complement(21106..>21370)
                     /locus_tag="PK679_03520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55058.1"
                     /translation="RLLDSLEEKDFDVSAIRAALGNGDTGTARTLLQQFLQQNRDALP
                     EKPARGDSPARGVSQAGNTDSPAVNNPASTGNTTVFRTRHGKG"
     assembly_gap    21371..21470
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<21471..21848)
                     /locus_tag="PK679_03525"
     CDS             complement(<21471..21848)
                     /locus_tag="PK679_03525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55059.1"
                     /translation="MKRLAYTLTLGILVGFLLLVTFPVQAIPSASLNARPDACGLDGT
                     GLSERMDRLLDSLEEKDFDVSAIRAALGNGDTGTARTLLQQFLQQNRDALPAPDTNQT
                     RMDRMDRLLDSLEEKDFDVSAIRA"
     gene            complement(21987..22178)
                     /locus_tag="PK679_03530"
     CDS             complement(21987..22178)
                     /locus_tag="PK679_03530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HPC55060.1"
                     /translation="MKNKIKVYRAMRDLTQEALAQELKVTRQTILAIEKGKYDPSLEL
                     AFKIARFFGVPIEEIFTYE"
     gene            complement(22168..22623)
                     /locus_tag="PK679_03535"
     CDS             complement(22168..22623)
                     /locus_tag="PK679_03535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2178 domain-containing protein"
                     /protein_id="HPC55061.1"
                     /translation="MKQNTFYLLVGVVGLVEVGLFMISVSLHNPLIIMAGFIMGAGLV
                     YVSRLMVTDIREDERSRLITQKAGLRTLEVFWIIFFAVSLGTAVIGFSTPLGIPRPRE
                     FPHDFPRDQPYLGYFGILQMILLCCIAFLYIAFRIYYARRYGEWDTDEE"
     gene            22743..23432
                     /locus_tag="PK679_03540"
     CDS             22743..23432
                     /locus_tag="PK679_03540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HPC55062.1"
                     /translation="MTFPSYPGRLLGTGTDSLPSIVFSLVLAPLLAFLYYFLCVLILP
                     LEKALILGGLMILYYIPPSGKESLIPVGIALGIPWWLMATSLALLDVLTSLFMILNIR
                     LALRLPVLGPWISGFLGKGDEFMKKRPWIARWSVLGVAFFVFLPFQGTGGVGATLVGM
                     LVGLSPLQILLAVAIGASAECLLFAVGSDIIWRLILGNISVGIPVAGAVLAAVVVAYV
                     LLRRWYGGEEE"
     gene            23611..26175
                     /locus_tag="PK679_03545"
     CDS             23611..26175
                     /locus_tag="PK679_03545"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HPC55063.1"
                     /translation="MQIFSFDSLSGLSSAEVSRIREVEGYNEIPSDRRRSPAAIILGV
                     FREPMFLLLVATGAIYFLLGDIQEGFLMLSFVIVIIGITVYQENKTEKALESLRNLSS
                     PRALVIRDGNLVRIPGREVVTGDYLVLSEGDRVPADGVLLYSQSLSVDESLLTGESVP
                     VRKTAGREGLEPSPPGGDDLPFVYSGTLVVQGQGLARVTAIGQKTEMGKIGRALMAVE
                     REDSLLKREVAGIVRKIAVAGMSLCAVIAVVYGLSHASWVDGLLAGITLAMAILPEEF
                     PVVLTVFLALGAWRLSRYHVLTRQVPAVETLGAATVLCVDKTGTLTENRMSVKAFCCN
                     GEVTPFGCRSDETVPDSCHELAEFAILACKKDPFDPMEKALLSLAAGEFGKTEHVHAS
                     WDLVQEYPLSPELMAMSNVWRSRDGSEFVIAAKGAPEAIADLCHLEPGRRTDLDNQVD
                     ALASQGLRILGVAKASFRPAALPDNQHAFSFTFLGLIGFADPVRPGVREGVAECRAAG
                     IRVVMITGDYPLTARSVGAEIGLPDVDHIITGPELDRLTDAELEERGRLTSIFARVVP
                     AQKLRIVQAHKKHGEVVAMTGDGVNDAPALRAADIGIAMGRRGTDVARESASLVLLDD
                     NFTSIVAAVRMGRRIFDNLKKAMAYIFSIHVPIAGMSLVPVLLATPLVLLPAHIVFLE
                     LIIDPACSIVFESEREEEDIMKRPPRKRDEGIISGKALQFGLFQGGVAFAGVLLVYLW
                     ALLSGMGDDEARTLTFVTVVAANLGLILINRSWTLPFWETLGLPNRAFWIVISGTLLC
                     LALVISLPPMRDLFSFAPVSATALLVASAAGVASVLWFEVFKFWKRKTAGNTATPP"
     gene            complement(26226..27779)
                     /locus_tag="PK679_03550"
     CDS             complement(26226..27779)
                     /locus_tag="PK679_03550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HPC55064.1"
                     /translation="MSSWSWNFSSCLSGLTGTGGAGGKRFPYPGGRTTPAEGEQWSSR
                     AGFILAAIGSAVGIGNIWRFSSVVGQNGGGAYLIPYFIAVFACAFPLMVFELAMGRSF
                     HGTVVGAFRAVRPSFRIAGWFLCATIFLVLCYYLVITGWTAAYALFSLAGVSITFADF
                     TASDMPVFFFLFSAAVTTGVVSRGVRKGIERVSVILIPVSVAILIVMALYVTTLPGFL
                     EGTVFLFSPDFSVLFDPLVWSAAFGQAFFSLSVGTGILLTYGAYMEKGIPIPRSALVI
                     TLADLGVALLAGIVIFPLVFTFGLEPAAGAELAFSTLPKAFALMPGGVIFAVSFFLVL
                     FFAAITSAVSMLEVGVSSLREAVSWSREKTSLLLGLVMVAIGLPSSLSYSAANWTVGG
                     VKILDFMDETVGTLGLPLAAVILAVSFSWFAPREILDREIGRSFAGIVHPLCKYVIPA
                     ILLGTTLARLASGIDLADLRLLPGSPWMGTLMQVGGMVLIGAGTLIVVSLLCRFGRCP
                     FGRRLFRKG"
     gene            complement(27670..30447)
                     /locus_tag="PK679_03555"
     CDS             complement(27670..30447)
                     /locus_tag="PK679_03555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HPC55065.1"
                     /translation="MIPGTIPHHGVPWHALPIGKVYEILRSGSGGLTRQEALHRLAQY
                     GKNTLPSRKAPGLLQVIIHQFKSPLIYILLAAGVISILIGDARDAAFIFLVVCINAAI
                     GTIQEWKAEQSAQKLQSLLRVTARVKRDGAWQNIPAEDLVIGDVVLLESGMKVPADMR
                     LLHTANLSIDESLLTGESVAVQKTVGITEEKAPVSDRFNMAFAGSTVVSGRGCGIVTG
                     TGTRTEVGLIAEAVSETESAKPPLLIRMEIFSRNVGALIVSASIVMAIAALSQGVPPV
                     EVFFLAVALVVSAIPEGLPVAITVALSIAASRMARRNVIVRKLAAVESLGSCTTIATD
                     KTGTLTVNQQTAQAVFIPPGTIVEVTGAGYDPGEGTFRIAGEEIPEQVAGAVRGLAKV
                     AVICNEGTLYREDGTWVHSGDAMDVALLALGYKAGLVPDDVRNGIENVAHVPFESERM
                     YAAVYYREGEDPAGPVKIAVKGAVEALLPYCRAMATPAGTVPFDPLLVGSHMETMMEK
                     GFRILAVAEGALRSAPGPDPGLEKTAPELTLNGLVGFIDPLRPDVKDAVRVAHGAGID
                     VVMITGDHPRTAFAIARDLDIAKDFGEVLTGKDLAAMGDPMLPAYGEVIDRTRVFARV
                     TPLQKMEIVDALVRRGHFVAVTGDGVNDAPALRRANIGVAMGSGTDVAKDTASMIVTD
                     DNFSSIVAGVEEGRFAYDNIRKVTYLLISTGLSEVVLFILALLAGLPIPLLAVQLLWL
                     NLVTNGIQGVALAFEAGEKDAMTRKPRPPGEGIFNGLMVRETLLSGLTIGLVAFLAFW
                     WFNASGTEETVARNLLLLLMVLFENFHVFNCRSEYQSVFRVPIPNNYFLIGGVILMQG
                     LHIISLHVPLMQEILGLVPVTLEQWLVCLCIAGTVVVVMELFKLFIRSDRDRRSRGKT
                     ISLSGREDNAC"
     gene            complement(30472..30969)
                     /locus_tag="PK679_03560"
     CDS             complement(30472..30969)
                     /locus_tag="PK679_03560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55066.1"
                     /translation="MTHLREIPPSTRWALASHVLTRLVLELGRTAARPGGSPDSQRLF
                     SLLGEEARRIADGNSMKRDNAADLVATLGTVSVILFGRAFETRYIEGFPEEGVIRLAE
                     CAMFREESAPCIPPAEIHAICSAYVKSVVEALNPEFSVGVSMARCRGDGFCEMVIARK
                     EQFRD"
     gene            31209..33191
                     /locus_tag="PK679_03565"
     CDS             31209..33191
                     /locus_tag="PK679_03565"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HPC55067.1"
                     /translation="MDLSILTDILIIFGLSLIVGLVFNRLRIPPMIGYIVAGVIAGPS
                     LLSLVQSPAQVDILAEIGIILLLFSIGLEFSFRQLWEIRSLVLSGGCIQVALATVLAT
                     AVALAIGRPWNEAVLLGFVVSLSSTAVVLKILHDRGELDSLHGKLTLGILIFQDLVAI
                     PMLMAVPFLAGVAGGTGDPLLVVILKDFIFVAILVATAKWVMPAVLFQIARTRNNELF
                     LLFVVCICFGIAALASFAGLSLAMGALLAGLLISQSEFSHQAISRIVPFRDIFTAFFF
                     VSIGMLLDVGFILDRPGLIIVFLIVVLAIKFIAGSLAPFVLGYQLRTIILTGIALMQV
                     GEFSFIITKSALDIGLLSRDAYQVFLVVALISMAATPFLILSGQPLASFVCSSRFFQK
                     VLPGRCQWVATEKKVARSGHLVIIGYGVNGRNLARAARIGGIPHVIIDMNPDSVRQAR
                     KEGEAIIYGDATTEGVLDHAGIRQARTAVVAINDPVATRRIVGLCREMNPGIFLVVRT
                     RYIVEVPVLREIGADEVIPEEFETSIAIFSRVMADFGIPDETISRLVHEIRSESYQFL
                     RNPASSPPIQALEIPGMEVRIIRVAEGAPIAGRTLGEVLLKKRYGVTVLGVRRDGAII
                     PHPDGTCEIRAGDEVTITGTKDKIAGAIFLFSPASD"
     gene            33281..34474
                     /locus_tag="PK679_03570"
     CDS             33281..34474
                     /locus_tag="PK679_03570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HPC55068.1"
                     /translation="MEGIVATPEFQVSLLLFAALGGYLLASRINQSAVVGIILVGLLI
                     GPSVLDLVTYNEFVRGLAHLGAVVLLFVIGFEFKLKDIVRPAYAFIALIGVIIPWLGG
                     YATALWAGMEFQTALFVGTALTATSIAITANVLQEMNKLQTDAARAIIGAAVIDDVLS
                     LIALAITGDVVAGAFHPSVILFILLKVVIFLLVAGAVGIFIVSRFLVRLDNTPFVARY
                     PEFIFIFAMTFAFLYAMIAELVGLSAIVGAFIAGISFERLTLRKSLDVKEGAEFLKII
                     FAAIFFVSLGVVADFKTLTPDILPFLVVLTIVAIVTKVVGCAIPARIAGICRKDSLII
                     GFGMAPRGEVAMIVALIGLEQGYIGQAVFVAIIVMSLLTTLITPIIYRNWFFKDENCG
                     PVQQI"
     gene            complement(34612..34950)
                     /locus_tag="PK679_03575"
     CDS             complement(34612..34950)
                     /locus_tag="PK679_03575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HPC55069.1"
                     /translation="MKITRLDDVTPQPNPHHVDARKVYDTEHAVAVVITLRPGEALKR
                     HITPVDVFFYVLQGKGTVEIGDERETVGEGTLVESPARIPHRWINESNAVFRVLVVKV
                     PRPTEETKLL"
     gene            35109..35906
                     /locus_tag="PK679_03580"
     CDS             35109..35906
                     /locus_tag="PK679_03580"
                     /inference="COORDINATES: protein motif:HMM:NF024211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC55070.1"
                     /translation="MPGPGPNTIQMVGIAYGILFVIAGALLWRSGRFSRTVRYALLLV
                     TILLGFAIFSPMLPYMFGELVARADSRVGATLLGATLGMVLFFLLTFLFGRHFCGYLC
                     PVGAVQEVAYVVPVPKVRLPWKILPVIVRAVVFLLIIGAGLVYSISILSYVGIRQFFT
                     LTLSAGFLVFSCLLIISVFFYRPFCRFICPLGAIFHVFAIPSRWKIRRTDACIECGKC
                     ENACPTSEAGREDTKGECYLCGRCMDTCPVKGTLIYAGKTSKEGTEK"
     gene            35915..36262
                     /locus_tag="PK679_03585"
     CDS             35915..36262
                     /locus_tag="PK679_03585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HPC55071.1"
                     /translation="MARESRKDLRGQVFALKDLVEYQPGTVASRMIINNKAGSITVFS
                     FDKDEGLSEHTAPYDAVVTILDGEAEVWVGGETHAMKEGQTIIFPANVPHALSATTRF
                     KMALTMIRGSEDE"
     gene            36255..36557
                     /locus_tag="PK679_03590"
     CDS             36255..36557
                     /locus_tag="PK679_03590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAC family transcription factor"
                     /protein_id="HPC55072.1"
                     /translation="MSEGGEGKYCTICGGIPPEEIKIRKILIDGKETGIDKLDFILEE
                     VFRLNCPTDQEIVAEILRRVRVFNYVPTRVTEKYGEALLEEYRRFVRDREIPGQIT"
     gene            36752..37435
                     /locus_tag="PK679_03595"
     CDS             36752..37435
                     /locus_tag="PK679_03595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC55073.1"
                     /translation="MTEELPGAILQRDGKSYAIVPRTPSGIVTPEELERIARVARKYR
                     IPVIKMTSGQRMVLVGLNKDDIPSVWRDLGMDVGQATAPCVHYVQACPGTETCRFGVQ
                     DSLGLGLAIEKMYKDLSLPAKVKIGVSGCPRCCGESHVRDIGIFGTPKGWTIVFGGNS
                     ATRPRIGDVVAKDLSAEDAIDLSRRLLEYYRDHGKPRERTARFVERIGFEAIRRDVLA
                     YTPYIPMGK"
     gene            37667..38152
                     /locus_tag="PK679_03600"
     CDS             37667..38152
                     /locus_tag="PK679_03600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HPC55074.1"
                     /translation="MNTCFIYHSYSGITRKLVEKVRAACGGDAIEVTPRQRYNALTAY
                     TLGCMRARNGQCDPIDPEIIDVSGYDLIVIGTPVWAFRATPAVNAAIASLRGAEGKKA
                     VLFATCGGTPGETIPRLRDALAGKGAEVIGEMVFTKKDTGDPEKIDALIRMVMDAAGT
                     S"
     gene            complement(38200..38394)
                     /locus_tag="PK679_03605"
     CDS             complement(38200..38394)
                     /locus_tag="PK679_03605"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55075.1"
                     /translation="MAKSSVRETVIGTRSGYVIRFTCPSCSKENSIVFNMPKAFYKES
                     RDGRCSRCKKLFTVLTPGQG"
     gene            complement(38732..38899)
                     /locus_tag="PK679_03610"
     CDS             complement(38732..38899)
                     /locus_tag="PK679_03610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HPC55076.1"
                     /translation="MYRSNFGGPRNFGPREMTKVVCSDCGKECEVPFKPTEGRPVYCR
                     ECLPNHRRPRL"
     gene            39161..39574
                     /locus_tag="PK679_03615"
     CDS             39161..39574
                     /locus_tag="PK679_03615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HPC55077.1"
                     /translation="MGDETEHMSTHRFFIDHPIRAKKVKLATGCCCELCGSSLPLEGL
                     EIHTFSIGMQSVPPQPAVLEEHLLVLCARCHADIHEFSLPVSEQEWLVRMRDGHKKEE
                     ICSILGYVPRRYTPPESDIEEAYREACSSRFRFGV"
     gene            complement(39580..40134)
                     /locus_tag="PK679_03620"
     CDS             complement(39580..40134)
                     /locus_tag="PK679_03620"
                     /inference="COORDINATES: protein motif:HMM:NF021886.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HPC55078.1"
                     /translation="MPKNAHARFIVLGVLGTRPMTGNEIRKWIRDFFCPSWKIGPKTV
                     SSSLRTLEEEGLVTKLHPPGDRGQKKDVYTITGKGKKEMQRWLQSPEENDSEVLLKCL
                     FGYHLPPDLLKEKVRAFRKRREDSIAEIEMRENRIAALPDTAVEKPFLRSAARNEIMT
                     CIAQVDWAQETLSLLETIEFPGKS"
     gene            complement(40232..41071)
                     /locus_tag="PK679_03625"
     CDS             complement(40232..41071)
                     /locus_tag="PK679_03625"
                     /inference="COORDINATES: protein motif:HMM:NF001664.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HPC55079.1"
                     /translation="MQRPLRERVTVVEGDITEQYVDAIVNAANETLLGGGGVDGAIHR
                     VAGPGLLGECRRLGGCQTGDAKITAGYNLPARFVIHAVGPVWRGGGHGEDDLLASCYT
                     RSLELAEANGIKTIAFPAISTGAYGFPLPRATVIAVRAVLSFLSRSDSIEKVIFVCHG
                     KRAFDLYTDAVRDLAGEYSPATGLGRNIPKTRGTEQELLLAQVRAQLGTIEEVWGVRF
                     VDKDRLAGTIMERCGDRWGADSVTAGLNSWVAVLGKRGDIEVPPAVLDRILDETRQRF
                     SHR"
     gene            41174..43765
                     /gene="mgtA"
                     /locus_tag="PK679_03630"
     CDS             41174..43765
                     /gene="mgtA"
                     /locus_tag="PK679_03630"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HPC55080.1"
                     /translation="MEGKPGLLAGDLHGQDLVALTEEEVLSVLATSKNGLPLHEVARR
                     QSQYGPNDISRVHKRSVILRFLDHFRNVLVLILLFAAVISFFVGDYPSGTIIVAIVIA
                     SVVLDFYQEYRAGNAAELLRQKILTHATVVREGAEHEVPLTDLVPGDIIRLSAGDIVP
                     ADARLLSGRDLFINESSLTGEPFPVEKRAGPVPTGTPLTEAKNYVFLGTSVVSGTAVA
                     VVTLTGMATEFGRIARTLVARPPETGFEKGLSQFSYLMSRFIFILVIFVFLINALFRH
                     GALESLLFAVALAVGMTPELLPMILSLNLSKGAIAMAEKKVIVRHLESIQNLGSMDVL
                     CTDKTGTLTENRISLIEYLDPDGAPSEKVLYYTFLNSYFHTGVQNPLDEAVISFRPLD
                     AGQFRKVDEIPFDFVRRRLSLVVDDGNERLLITKGAPEEVLSICTSIERGEKTDALSP
                     GDRESVIALYHEKSRKGFRTLAVCTRKLPRDRAVFSPEDEREMTLLGLVTFLDPPKES
                     AGESVRALAESGIDLKILTGDNELVTRRVASLIGLEVRGVLTGREIDQMDREALSRVV
                     EEVTLFCRLTPVQKNRVQNALRKNGHVVGFMGDGINDAPAIREADVGISVRNAVDIAR
                     ESADIILLENDLRVLHDGVREGRKTFANTLKYILMGTSSNFGNMFSVAGASLFLTFLP
                     MLPIQILLNNLLYDLSESTIPTDNVDEDQVRSPKRWDMEFIKRFILVFGPISSLFDFL
                     TFFILLSYFAADAPFFQTAWFIESICTQTLVIFLIRTRMVPFFRSRPSRLLLASTLSI
                     VAAACLLPFSVLGEVFGFVHLPPAFYLVLAGLISAYFFLVEVAKKWFFGKYSFLIEQG
                     KGNALVA"
     gene            43866..44813
                     /locus_tag="PK679_03635"
     CDS             43866..44813
                     /locus_tag="PK679_03635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HPC55081.1"
                     /translation="MRVPSPRPFLKWAGGKTQLLPALVRMVPRKVREGEVPVYVEPFV
                     GGGAVYFHFNSRFRFRECHIFDVNEEIFLAYTVVRDRVDELIEVLQELAGEYLSRDGA
                     GRREYYREVRDAFNNRRITIARGQFHPSWVERAAQLIFLNRTCYNGLFRVNSRGEFNV
                     PYGRYRNPLIVNEPLLRQDSLLLRNTSVHLGDFSRSFPFMSEETFAYFDPPYRPISRT
                     ARFTAYSQDGFSDAEQERLARFFAACDAKGALLMLSNSDPRNTDPCDDFFDRLYGDFS
                     ITRVPARRAINSDGAGRGSISEVVVTNYPIGRSGTLSLE"
     gene            complement(44866..46761)
                     /locus_tag="PK679_03640"
     CDS             complement(44866..46761)
                     /locus_tag="PK679_03640"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55082.1"
                     /translation="MTMSSFLSRCENLDILPAGIIILESDYTVICWNRTMEEWTGIPR
                     EKVLGRDLRDLYPHLSDRKYALRIGQVFEGGAAAFFSTQFHPHFIPAPLPGGGLRFQR
                     TTVHSVPEGNKTYALVFIDDVTELVQQVRAYREMRDRALREVRERLEKEAALEESEAK
                     FREIFESANDAIHIHELREDGLPGRFIEVNAVACKMLGYSREEFLAMTPLDLVRGGHS
                     RPLDVIGREILEKGYAIFETEHRRKDGGTVPVEIHAHRVIIRNREVVLSVVRDITERR
                     RNQAALLALTTELQTIFDNAPAMIWYKDTENRFIRVNPAAAASIGLPREEIEGKSAYD
                     LFPELAEKYYRDDLEVISTKKPKLGIIEQMQTRNGGIRWVETHKVPLLDLEGNVSGIL
                     LFVNDITERKMAEDALALANRKLHLLSSITRHDLLNQVSALKWYIELARDEKELTTIR
                     EFLDKMKKVLDTAEEQITFTRDYQEIGVREPSWQNVADIAARIREGFPPSGVDILLEV
                     DDIEVYADPLFEKVIFNLFENSFRYGGPSLSRIRVSAGEEQGGLVIAVEDNGVGIPEE
                     DKKYLFRKGFGKHTGLGLFLSREILAITGLSIRETGVPGKGARFEIFVPEGKFRRLTR
                     ERTGEKG"
     gene            complement(46758..47366)
                     /locus_tag="PK679_03645"
     CDS             complement(46758..47366)
                     /locus_tag="PK679_03645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HPC55083.1"
                     /translation="MNAGEESIDAIRELINIGVGRAAGLLNDMTGTHIRLQVPEVRVL
                     RYSDLTREQRLLDSAHLSAVTLRFSGSFSGMSMLVFPEKSAAILIMALTGEKIEEPDL
                     DALRIETLNEVGNIVNNAVMGSITNVLGERLIYSIPEYREGGIGDILGREGSPDYDWV
                     ILAVSQFIIEDLRVVGNILMIFEIGALDTLLEKITAVMGSHS"
     gene            complement(47363..47734)
                     /locus_tag="PK679_03650"
     CDS             complement(47363..47734)
                     /locus_tag="PK679_03650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55084.1"
                     /translation="MAKILVIDDSRFQRKLISSVLEEAGYQVLTAGDGREGFTVALGE
                     SPDLVICDLLMPGIDGYTFLRMVREEGLGTPVLVFTSDIQKTTRDICLELGAFDVLNK
                     PVDKGVLIPAVGRAIGSAKKS"
     gene            complement(47826..48578)
                     /locus_tag="PK679_03655"
     CDS             complement(47826..48578)
                     /locus_tag="PK679_03655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55085.1"
                     /translation="MSEYCTGVCTGFSAAWAIARKDILIYYAKPNIIVSGMLFPLFMF
                     LAFAVGRPADPATMVPGLIAITILFSSSSIEPVSIPLERRTKTFERLLSAPISLHMVV
                     LGESMSGFLYACCIALVPLAAGMVLFQTSLPDLPALAAGILLLSFCFATMGTLFAAYP
                     TESPGDIMSMLNLVRLPLIFVSGVFVPIGQVPFPGQIIAYLSPLTYGNDLVQAGFGKA
                     TLFHPAIDIAALCIAIGIFQSLANRLYRTFNE"
     gene            complement(48584..49534)
                     /locus_tag="PK679_03660"
     CDS             complement(48584..49534)
                     /locus_tag="PK679_03660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC55086.1"
                     /translation="MHAIEAISLEKRFGTIQALAGISFSVEEGETFGFLGPNGAGKTT
                     TIRILTGMTEPTGGSGRIFGRDVVQEKIPARREIGIVHETSNIYTDLSAWENLMFTAR
                     LYNVGKRERESRALDLLSVFGLSGRKDDKTKGFSKGMKRRLTIAMGLINNPRLLFLDE
                     PTSGLDVQSNLIIRDVIRRLAGEGVTIFLTTHNIEEANILCDRVAIINRGRIAAIDTP
                     ERLKKTIQSVQSIEVAFDPPGAVRAEDLAGIDQVTGVRKMGDKIRLITGDPPAVIVGV
                     TDYARRSGLRIISINTLGPSLEDVFIRLTGLDGEGGGGGP"
     gene            complement(49718..50131)
                     /locus_tag="PK679_03665"
     CDS             complement(49718..50131)
                     /locus_tag="PK679_03665"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:NF024970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC55087.1"
                     /translation="MTGWSHLTLRADRRNLGEVFGFLRQVLGEAGIRERLLLDLELAV
                     EEAVVNVMTHAYPGGEGDLVLGVMPGPDHVTIELRDRGVPFNPLLVPEPDISAPLGER
                     EVGGLGIHLIRTLMDEVSYEFRDGENILTFRKRRD"
     gene            complement(50128..51516)
                     /locus_tag="PK679_03670"
     CDS             complement(50128..51516)
                     /locus_tag="PK679_03670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HPC55088.1"
                     /translation="MDVPTGLLTEYAEIIHVLFQLVCVLSVIAYLLSRTPTFRDVVAG
                     KLTWKHQAFLVLVFGALSIYGTWGTIEIMGAPVNVRDLGPMVAGLLGGPVAGLGAGLV
                     GALYRSGMGGFTVVPCCLATVIAGLLGGLLWLSSGRKFIGVGMAVLFAGGMEVLHNGL
                     VLSMAEPRSMAESLVAQIGIPMVLANAGGMFIFAFIISNLAAEQKTKGERDTYHAELE
                     RKNAELAVARQIQESFLPESIPPIEGFDLAARSIPAKEVGGDFYDVIVRGPGEPFGLI
                     IADVSGKGVPAALFMALSRTVTRANAMWHRSPLQCISDANRMISADARYGMFVTLCYG
                     VVDPASRTVRYVNAGHNPPLLVRADGTRADLGITGPALGAIGDAEYTDAHVTLSPGDI
                     LVFYTDGVTEAVNAQDEEFGAGRLADAVVASRERTARDILDAVMESVARHARGMPQFD
                     DITLLVLKVGLP"
     gene            complement(51541..51894)
                     /locus_tag="PK679_03675"
     CDS             complement(51541..51894)
                     /locus_tag="PK679_03675"
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HPC55089.1"
                     /translation="MVSAPFQVSTKQDRDVDIILFSGRMDANSSPEGENAIQSLVRSG
                     RTKIVVNASGLSYISSSGLRVLLAGLKQARQAGGDLRLACLQPQVRDVIAMTGFNRIF
                     TIFEQEEQAVGSFFS"
     gene            52290..53966
                     /locus_tag="PK679_03680"
     CDS             52290..53966
                     /locus_tag="PK679_03680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC55090.1"
                     /translation="MRIFPFFGKPDCTSSNLCLIDTGSEFIVIDTGTNERQLEDVVRL
                     VREVPGGSLRPVILFITHCHIDHCYPLLAGSLLDRLPLFVAAQEVGAAAIATGDVQLT
                     LGEMFRKQLKPHAVQIPLLCTADRERGGEKILSVPGLGSVRLLTDVPAATGPLHTVSQ
                     QVILPPGTCLSVYSTPGHTPDSICVRIGSVLFCGDILFATTPGVAGIRGFSRDDLLST
                     IRTLQAIVDAGEITVWIPGHGDPLGNPAMARALHNLEREVLSLREIHTFDLSRLEESR
                     DHALDILDEAERLFAIIGGRLLALSFILESLGEEAEAEKFREVMDITATDTVLCDFQQ
                     FCADVRAGKRVEVQLIPKAVQVLQKLRRSLSCEEVSGVVDHSIIWRAERLLDEFLATA
                     RDIPRDPTPDQVDLVSLLESLVTTAHCPPVPDEEFIAAAEDAEAFRKALVARLAFLPP
                     VPALSLALDRKKTDIPPVASDRFRLSDSLMALLEDLEAAGCRDARLGARQRGSAVELV
                     IEAGCPGKKEILSPRLTRRHERRFHLCGGEFSAAREGDRITCTVSFVAAR"
     gene            54015..54392
                     /locus_tag="PK679_03685"
     CDS             54015..54392
                     /locus_tag="PK679_03685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55091.1"
                     /translation="MAERPLGVTIIGILWIIGGILALLGGLGIAVLGGAIAGPLGAAF
                     GLVIGFVLVIIGLIDIILGIGCFKAWGWVWTIGVIITIIGLILGIIDLVQSGASALIG
                     IIISIIILWYLFKDNVKKYFGKA"
     gene            54632..55513
                     /locus_tag="PK679_03690"
     CDS             54632..55513
                     /locus_tag="PK679_03690"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55092.1"
                     /translation="MIDILCVDDDPDFLEITKRMVERSGAISIDTASSAENALAMMEH
                     RAYDVIVSDYQMPRTDGIEFLKTLRKSGNTTPFIIFTGRGREEIVIRAYDSGADFYVQ
                     KGGDLKAQFRELEHKIVQAVRIHEAESAFRESEERYRSVVENATEGIVVVQDERILYA
                     NPRALEMVEATPDEVTGKNFALFVHPDDIPLVTGRYYKRQEGVPIPKTYDFRIVGKGG
                     HVTWVQASAVLIPWNRRPATLALLADITERRERENGVRQRNVDLEKTVEDQAARLEKS
                     ENEKKDLLRRLAGDDAG"
     gene            55685..58720
                     /locus_tag="PK679_03695"
     CDS             55685..58720
                     /locus_tag="PK679_03695"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55093.1"
                     /translation="MTNPYRILYVDDEPALLDIVRLYLERKKRFIVDTATSAGEALKM
                     MQGNPPYDAIVCDYQMPVMDGVGFLRVLRKHGDDTPFIIFTGKGREDIVIQALNEGAD
                     FYLQKGGDPASQFAELAHVIQKVVRQKRIESSIRDMERREADILNFLPDATFAIDLHG
                     TVIAWNRAMEKMTGIPADQMLGKGDHEYALPFYRERRPILVDLILQSDPGTEARYPYI
                     RKEGETLISEIFIPSFNDGKGAHLWFLASPLYNSRGEVVGAIESIRDVSEWKDMEKEM
                     EERGRFLSTLVANLPGFVYRCRNDRNWTMEYISDGCRDVTGYEPSDFIGNATLAFNDI
                     IHPDYRNVLWNLWQEILADRRVFEYEYPITTRHGETRWVWERGRGIYSEDGTLLYLEG
                     FITDITARKNVEDELRKSREQLALAIEGSGAGLWDWKVQTGELSCNERWAEIVGYTRD
                     ELEPLSIETWTRLVHPDDLEVSNSLLQKHFAHETTSYECEVRMRHKDGHWVWILDRGK
                     VTEWDGEGRPVRMTGTHLDITERKRIEEELRESREILHNFIGNLPVGLYRNTPGARGE
                     YIMANPYIARLHGFETLDELFTHPAADLYEDPSERLAFSDELVRAGSVFGRELQLRRK
                     NGERFWGRVSAVAVRDEKGNVKYFDGVIEDITEQKKAEKAFRESEKKYRDLLEKLPEQ
                     VIVHRGGLILYANPATFRTLGYKPEEVINRHVLEFIPPEYHPRVVETLRKRDAGQETE
                     YYEIEILGKDGTRRTMRVSGNPITFDGEPATLIVLFDITERKRAEQALQQANRKIALL
                     NSVTRHDISNHLLVLTGLLELLQDTMEPSERADLLDKVRRAAARISAAIQFTKDYEKI
                     GGSDPQWQDIHDLVETAKADFVSPELVIENQIPRGLLVFSDSMLAKVITNLIDNSVRH
                     GGNVTSIRFSTAGEGKNLLIAYEDDGAGIPDGEKEMIFERGYGKNTGWGLFLSREILA
                     ITGMSIRENGVPGEGARFLLTVPGGSWKYVTLPAAGKET"
BASE COUNT        12452 a        16941 c        17007 g        12630 t
ORIGIN      
        1 agggggggag attcctgtcc ggtggtggcc tgcagggaga gaaggaagag gttgcggtgg
       61 aacctatttc ccctttatcc ggggttcgaa tccccggatc agccccatgg caaggatgag
      121 aaccgggatg atctcgagcc tgcctgtcca catcaggaag atgaagaccc atttgatcgg
      181 gagcgggctt gccggagtca ggtatccgag tccgagcccg acgttgctca tcgcggatat
      241 ttcctcgaag atgacctgat gcgtcctgaa cccggttggt gcaaggtgca ggctgatgac
      301 cgttgcaaga aagatggtca ggacataaag gacaatgatc agcatgttct tggagagttc
      361 cacgtcagat atccgcctcg ggatggcccg gccctcgtgc cggaagggaa caatgaccct
      421 gccccgcgag aagaaacgcc tgaaccacca tacgagaccc tcgtagccaa ggatgacacg
      481 gtttgccttg ataccccccg atgtacttcc ggcagccccc ccgatcatca tgaggagact
      541 gatgatgatg aggggcgagg cgatccactg gaggttcgag ttctgcagcc cgcagcacgt
      601 aaggcctgat accgtgcaga aaaagccctg gcggacggct gtttcaaggg gaaggccgtt
      661 gaagaggtgc aggtcgatgg tgacgatcag agatccggca agggcgagaa agaggatgag
      721 ccagaccacg cggtcctgga gaaacggccg tatttttccc ctgtatatca ggaaatagag
      781 cttgaagggc agtgcacctg caagcatgac agggatgagg aggatctcga ggagggcatt
      841 atcgtagtag gaaacacccg cattatggag ggaaaaacct cccgtagcaa ggctgaccat
      901 gacgaggttg agggcatccc acaggggtat tcctgcaaac atgaccatgc ctgtgaacac
      961 cacggtgagg aagacataaa tcacccacat cctccttccc gtggagacga cgtttggcat
     1021 gagatcctct gatctcccct cggcccggta gagctggtgc tgggtcagcc cggaccggga
     1081 aagcatcgcg ataccgaagg caatgacccc gatacccccg agccactgca tgaacgatcg
     1141 ccagaagagg agagtcttgg gagtcgtatc cagattatcg atgactgaaa aacctgtccc
     1201 cgtccaccct gacatcgact caaagatgct gtccgtccag ctcatatgca tccctaaaac
     1261 gaagggaaag ctcccgatca gggcaactgc tacccaaatg agtgcaaccg cggtgagggc
     1321 aaccgagagc tgcggcacgt actccttccg gggtatatgc gagatgagta ggccaaggag
     1381 accgaacgtg agggggaccg aaaccatcgg cagaaacatg tcccattccc cgaatacgac
     1441 caccacgagg aagggcagga gagtgatcaa accgaggaac tcgaagatgg cccccatgtc
     1501 atgggcgatg atggccaggg tctccagcct cttcatgatg gatcacgttt ggtggacgat
     1561 gttatcttgt ttctccccgg ttggcagagc ccccatgccg tgggaagggt gcaagaaaag
     1621 gagggtcaag ttcaggctgt tcccgggaac tcaaggggct gcagtatgtc tcccggtcag
     1681 ccccttcctg ccataaaaag cagaaaagat accatatatg aagttacaaa ggtccggtat
     1741 gcaggccttt taagacatcc cgtacatcct cagtgtcaag tttctcaagg atcttcattc
     1801 gtaggaggga atcatcacca tccggcagtg cctgactgaa aggtggcgaa cagtcagcaa
     1861 cattctcctg cccctggtct tcctggttga cattcctcac catttatctc acccggtctt
     1921 cgggatgcca ttgaccctgc tggtgctgaa ggttacaggg tcatcagact ggtctttctc
     1981 accagaccct catatatggc acatttctat taaatctcca tgtatataat aattgcgcag
     2041 aataatattt ttacgataaa aaaagtggca tctggctata ttgacttttt ttctcatttc
     2101 gtgcagttat acaacgagaa acgggagcgc aaaaataacg taaagtgagg tggcaatgat
     2161 ttaatccgga aagaccagtc acataattat ggagcgaggg ttgccgagag gtcaaaggcg
     2221 atggatttag ggtccattct cgcaggagtt cgggggttca aatcccctcc ctcgcatggg
     2281 gacacgaggt tccattttcc accttttcct tttacaaaaa aggcagttgc aggatcttct
     2341 tttttcaaag tatggatacc aaatcatggt ccccttaccg gcgtgggaga tgtggattga
     2401 aagtataccg gcagcgcatc actcttcgtt ctcctgatta cagggaatac aggaacggtc
     2461 gggaaggtgc gtttaccgtg cgttccagat ttcgaaccga cagaggttgc tcccggttgc
     2521 ataacaattc ttctcgatgg cttcccgggc ctcgccgtgg tgtgcagaaa agagggccga
     2581 gagcacacca cccccgaatg aacattcagg ttttcccgtc agggggaggt ccatgcattc
     2641 gaagcagtcg cggatgacga tggtgaaggg gtcatcccgc tcgagttcca tctttccaag
     2701 cccgaacttc tcccaaaagc acgagatgcg ggaaaaaaag gaaagcgtgt cgtcgtcctc
     2761 gacgaggtgg tagattgcct ttcccgcccg gcgccctgcc tgggaaagga tgggatgtat
     2821 ctcgatcccg tctgatatca ggcttacgcg gagcgcggtg aggatgaagc tgaagacgtc
     2881 ccgggtcgtt gcatccgggg gcagcctgtc ggggaagaaa ttgtcggccc atttcatgtc
     2941 acggtcgagg gcgagggtcc ggatgaggat tctcccgttc agggagaaga gccggcggcg
     3001 tgcatccgaa ggatcgggac gtgagacggt gatgcctgcc tcgctgagcg ccttgaggtg
     3061 aacggaaatg gttgacttgg ccttccctgt ccgggtcacg atctcctcga agtccatctc
     3121 accggcttcg agcatctcga gtatctgccc cttgagaggg ctgtcgatgg ccttcaatcc
     3181 acgttccgaa gtacagatct ggatataacg ttgtttatcg ccctgatcat gattggaccc
     3241 ggccacctgc aaacctccac tcccatgaaa atggtcacaa aaagtataaa tacatatggt
     3301 tcgtatatac taaaacgttc gtatatattc gaacaatctc atgccgtgga tggaaaatcc
     3361 cgccatggga tgatcaggcc gggggatgcg ctccgtgtca ggcggggatg accctggcac
     3421 cgggagacgt acgaatatac attaaaaaaa ggagacaagt gcaatgacac tggtatcaac
     3481 cccgacccag acagacggga tcgaggtgag gaggcaggta accacgatcg attgcctgcc
     3541 atcatctgca agggcggtct acatgctgct ctcggacggc aaggagagga ctctgaacga
     3601 gatcatcgga cgcgtggcat tttcgccccg gacgatacgc aatgcgctgt cacgtctgcg
     3661 cgagagcggc ctcatcatcg ccaagttcaa cttcagggat gcacgaaaac ccctctacag
     3721 gttaaaaacc gcttaaaccg gccttttgtc acccttcaac cgggctgccg ggccggacaa
     3781 tccctgtttt ttccgtattg aaaaaaactg gtactccgga ctgtccggaa tatgcctgtt
     3841 ttgccattca gcagaatgaa agagaggggg tcttttttta cgccgttatc gtttccggta
     3901 tggcgatcgt tcctgcgggc tacccgccta tacctccaca ttgaagaaga cgcggataaa
     3961 gaccccgatg aggaacgaga ctgcggcaat cccgagagaa agggcagcca tctctgcaaa
     4021 cctccgaccg aacgggaggt cgagtgtcac cgaggtatac ccggtaaacc cggtgatgat
     4081 gagaattgcg cagatcaggg tcatcaggaa cgcaaggaaa gggttggcag tcatgatgaa
     4141 tggcaggacg agcacaagga cggtgaagat gtatgcagct cccgtgtaaa gtgctgccct
     4201 gatgggatcc agcgaactgc gatctgattt ccgggagagg tattctgatg ctgccatcga
     4261 gagggcagca gcaataccca tgatacttcc cactgcagca atcaccaggg aatcctggag
     4321 tgcaaacgtg aaacccgcga ggctccctgt gaattcaacg agggcatcgt tcagcccgag
     4381 gacgatcgag cccacgtaac ggagtttttc ctcggagatc atggcaatga tcgagttctc
     4441 gtgctgttcc tcatcccata tgacctcttc gattcccgga acacggtcag acactgcacg
     4501 gtatgtcctg atggtgctgc cttcgcccct ctccatgagc ttgatggcaa aggtaactcc
     4561 aaggagcttt gcaaggatga cataccacca gacgcgaatg gtgtccggtc cctcttcaac
     4621 ctctgcaatt ttctgccaga accgcgaatg agcaagttcc tcgcgggcca ttttctgaag
     4681 gacgctggcg tttctttcat cccgcatcat gcctgcgagc ctctggtaaa tgtggtactc
     4741 cgttacctcg tccttctgga aagagcgggc agcctccatc aaatcgggat gaggttcccg
     4801 atccctttta acggaaggaa tagcgatacc cccttcccat tgctgtaacc cgggctgtct
     4861 ccatgatttg taccatcaca aaatatccct gataagatcc ttctcccaac aatgggtatg
     4921 aaacggatta ataggttctt tttttgtcaa aaactgctac cggcagttat ttatggaact
     4981 ccggtgcact ttcccgtgac cgggacgagg gaaaggggga tttcctggat gaaaaaggtc
     5041 cttatcacgc tcaagaaaga cgatgccccg aatatcaccc agttactcgg cggtgcgtat
     5101 tcctaccggg aggagattga cgacagggtc aggtttacgc tcgttgttcc tgatacaaaa
     5161 ctcgatgacc tggtatcacg gatccgtacg gttttggact tcgtcgacaa ggagactctc
     5221 gtcgaggtct attcgccgga cttcaccatc tttcccgcgt tcgacgagaa aaaaaagcag
     5281 gaagaaggat cgcgggaaaa gaagaaggaa aagtctccta tcgagaaact gcttgcatct
     5341 gttgaatcgt acgagaaact cgataccaaa atcctgactc ttgccggcgt cgccagcatc
     5401 gtgggactca tcgggctctt tctaaacaac gtcgggatca tcatcggcgc gatgctgatc
     5461 gcacccatga taggtcccat atactctttt gcctccattc tgcgaccggg aacggtatcg
     5521 gtgttgcccg ggatatcttc aacatcttca cccttctcct cgcattcatc ctgttctccc
     5581 tcgcagtcac gtggatcatc ggttttttcg tccccctgga agtgaccggg gaaatacttg
     5641 cacgcacgca ccagagtccc gtctatgcca tcatggcgat attccttggt tttgcgacga
     5701 ttgtggcact tgcaaaggga atacccgata caatcgccgg agtggcggtc gcggcagccc
     5761 tcctcccccc tgccctcgtg agcgggcttt cgatcgttct ctatcccgga gggactatca
     5821 gcgctgtcat cctcaccctc cagaacgtca tcggcctcat ggccggtgcg atcattgcaa
     5881 caatagcact ccagatcagg ccgaggtcct ataaggagac acaggctgcg cgcactatcc
     5941 tgatcaggat tgccacactg ctcctgatcc tcatcctcct gctcctgctc ataccccttt
     6001 tttgaggcag gccttttatt ggtaaaacag gcggttaact cccgggtggg atcggggcaa
     6061 agggacggag gaggatctcg tggggcaggc ctgaaagggc tattgcagca agggcaccga
     6121 tcctgcccct tcccccgaag agctccacac cgttttttgc agcaaccgct tcagcctctt
     6181 tttcatcaac taccccgctg cgtgccttcg atccgaaggt acgaaaaatc ccgggaatcg
     6241 aaaaacctct tcggaacgcc ataccccatt cgggcgaaag cgactcgtcc tggatgaata
     6301 cgagtgccct gttccggaca tcctcgtatc tttcgggagg aattgcgatc tcgatgtaac
     6361 tgcatgagtt gcctgttgtc ttctcgggga tggcagtatt gagcattacg atgtggtggc
     6421 tgatgggaag cacccctttg agggtctcga ggtgctggag gagtgcaagg gccatggcaa
     6481 aagtggcacc tccttcacgg gaatccgtgt catcgagacc gatgaccagg tgaacgaggg
     6541 cacgggtcct cacgctccct tccaccagcc cgccgctttt ttggattttc acatcgcaga
     6601 cgccttcggc tttcgccatc atgtcggtga gggaatacgc cggcccgcca atgcaccgga
     6661 tgtgctgtat gatgtcgttt ccctctctct cgacccctgc gaccccgacc gcggaggcag
     6721 gatggagccc gatctcgatc ctgctctgtc caagatgggc cctttcacgg agaagcgggc
     6781 cgtccctcat cacgtcctcg agaacgccgc ccgcgcgcga atggtggtat gcacaaaagg
     6841 ctgcacacgc attgctcatg cactcgtggt aaatctcgac cctgtcccca tcgacggtcg
     6901 tgaatatccg cctgcaggca ctcgagggaa gtgcactgat ggcagcatac ttcgccgggt
     6961 tccggcccag cttccgttcc ttcaggacaa cgcatccttc atcgaggaga cggttaatcc
     7021 agtcctgcgc ggtactccgg gggactccgg cctgtttctg gatgtctgtc acggtaaagt
     7081 agccacggtc aaccgtgcag gcccgcatca gcttgaggaa ctcacggcgt tttcttatga
     7141 cgcccctcat ggaaatcccg gatatacagg aggtcaccga tgattgcgct tgccgtttcg
     7201 accgacccgg cacccttgcc tatcagcgtg atctctcctg ccaggtctgt ctcaatggtg
     7261 atggcattca gtgtcccgtc cacgaccagc ggatgggaga gaggaaggag gcgtggggcg
     7321 acccggagga tacccctgtc aggaattgcc tcggcaatca gccggatggt gcagtcctgt
     7381 tcctcggcga ggcggagggc atcgttcgtg agcatgtcga tccccgtgac ttcgacgtcc
     7441 tcgagctgga cgggcttttt ccagaatgta tttgcaagga tgacgagctt gatggcaggg
     7501 tcgataccct tgacatcgta ggttggatcc gcctcggcat accccatctc gcgtgcctcg
     7561 aggagtgcct gctcatagga gagaccctcg gcagccatcc ggcagaggat gtagttgcac
     7621 gtcccgttca ggaccccgaa tatggcaagc accctgtttc ctgccagtcc ctgctcgagg
     7681 gtgtggatga tgggaatcgc cccccctacc gtggcttcgt accggaggag gacccccttt
     7741 tcagcggcgc aacgcctgag acgttcgtat tcccgggcga tgggtccctt gttggatgtg
     7801 acaacgtggc gtcccctgtc aagggcggcg aggatgtggg acagacccgg ttcacctgtg
     7861 agtgcattcg tgggtgtgac ctcgacgagg acgtcgtatg tgcccttcgt gacaacgtcc
     7921 attgcggaga gggacgtgtc cccacaatac ccgcgtaacc tctttgcttc gagcacctca
     7981 tcgatgctta tcccgtccct gtccatgatg gcactccggg aatcagcaac cgcagtgacc
     8041 acgagcccga gatccctctc gctgatgacc tgcatgaggc cctttccaac cgaccccatg
     8101 ccgaggatgg caactttcat tcgatctcct ccagcggctc gacgagcagg aagtttttct
     8161 cttttgagac accgcggagg atatccatcg cctgttccat gtcctgcctg ttcacagcct
     8221 tgacgacaag ccgtgccgat gagacctgcg tgatggcggg catgcagata ttgaggcctg
     8281 tgacttctgc aaaaccggtc ctgtcgatcc tgtcgacggt atcgccgaga tcggtgtgga
     8341 tgaggtgccc gatcacgatc accgtttttt cgtagagaag cctctcgtgc ccgatcctct
     8401 ggatattcac accctgttcc cggatgagcc tgacgaggtc ggagagccgc tgatccggca
     8461 gttcaagtac tatctggaca ctcaatgtgt ccccctttgt tgccttctcg tccctctggt
     8521 ggataacagc gataatgttg ccccccacct cggagatggg gcgaagggct gccaccagct
     8581 gcccgggggc gtccctcatc tcgagtttca tggatacctg cacaggttca cccgcacagg
     8641 tatgtgtgaa cgcgaaaaaa gataagcctt ttaccctcct gcggggtgcg ggaagtcttt
     8701 tttaacccgg ttctacgtgt cgtccccgat accgtagtat ttccggatga attcacggat
     8761 cttctctgac tcgacccatc cccggtcaag ctgggcgacc gtcttctcga tctcgtggac
     8821 ctgttcgcga atctttccgg caaagggacc cccttccaga tcggcaaggc ccatgattac
     8881 ctgcacggga ttccggatgt gatcaccgag aattgcaaac tgttcgatgt tcttctcgat
     8941 ctgctggtat gcccttttct tctccctctc caggtgacgg gccctcgtga tgtccctcat
     9001 gatgatcatg acccgcgtga cctcttcggc ggcaataacg ggaatgagat gggcctcgaa
     9061 gaaataatcc tggccccgga aatgaaaatc gaggatagtc tccccgtctt tcccggtctc
     9121 gaacacggaa cggatcgtgt cggaaacctg gctgctgatg cagggaacgg cttccccgac
     9181 ctccatgccg attacattgc cttccttccc gatatgcgac aaccagcgcc ggagggtgga
     9241 attgaggagc acgatcctga agtcccggtc gacgagcagg attccgtcca tcattgcgtt
     9301 taatgcattt acgtactggc tctgggacgc ccggagttct tcttcagcct tttttatggc
     9361 agtgatatca acgagggtca ggacggtcct tctcccgggg acaggacctg ctgagaggag
     9421 gccatggagg atatacccgt ctttcctgcg gaggtgacac tcgaagtctg tcaccgttcc
     9481 cccgcgactg atactttcca tgactctctc cttctccgga ccgaccgcga agaggtcgag
     9541 gaacggtgtc ccggcgagtt ctcctgcccg gtatccgagg agttgtgcgc ccctgtaatt
     9601 gacttcctcg atcacgggtc ctgaccgcag gttaatgacg aggaataccc cggcctccga
     9661 gtaatcaaaa atcccgtggt acctcttctc ctgttctttc tgcgtgccgg aaagggatcc
     9721 gacaatcaac ccgattgcga caaaaacgta gaagtacgca gttgcctggg cgaggctctc
     9781 gacctcggga tacctgaaga aatagaccat tgccatgtac cccatcgcta tgacgacggt
     9841 gagtgtgacg ccgttccggg taaaccagta ggcggcgatg acgatgggga tgtagaacag
     9901 gtgcgacgtg atggagagga gacccctctg catgccgtaa tagttcagga agaatgcaaa
     9961 cagagtggac aggataagaa cggcaatcca gaaacttctc ttttcgagga gtgaagggat
    10021 tgctcttgtc agtgttccca tctctctatc acccgtccct gcacctaaaa tgaatagcgc
    10081 ctctccctat aaaaggtgtg acaccagaga cccccccggc ggtcctgtca cgtccgttcc
    10141 aaccgcgccc tccctgggga tacccgcggt ctcatcagtc tcccccgctc tcaccccggt
    10201 tatcggcgga tgtatcgcac ggcacgaggt ggtaccgggt cgcaaaatag tgaaaggact
    10261 ggttcttccg gcatgccacc ggtgccgaga accgggagag tatgtccagc atgaacgcga
    10321 tccgcgagac aaagtggcgg ggaatgcgtg aattgaagta ttccttcgag aggtcatcag
    10381 tcgaagagtg gtggggtaat gaaagatccc tttctgccgc atcgtcgaga ccggcaaggt
    10441 accaactttc tatctcccgg atgattatga tgatctcacg gctatcgaga acgcagaacc
    10501 gctccatcag gagatgtttc ttggctttca ctcccggttc gttatcgatg tctgcgaaca
    10561 cgagaaagtc atccttcatg cggtggatac ccgtcacgag gcggcagacg ctggcccttt
    10621 tcatgcaggc aaacttgacg atgtggaccg acctgtaccg ggactcgaac aggggaacga
    10681 tgacctttgc gaagaaccgc tcgtcatcgt ttccctcgac gaagaggaag agtctgcgcc
    10741 tggtcattcc agtccgagga ggttctggat gaagagatcc tcgattccga tctcctgttc
    10801 gaggaactcc cgtatctcct gcctgttcgc gggccggctc acgttcgaaa aaccatcgcg
    10861 atcgcgggtt atgagcagaa tgtcatcgat actgacatgt ttcagcatct ccgggttgtg
    10921 cgtcgtgaca atgacctgct tgttccgtga tgcatctttg agcatctcca cgagcttgga
    10981 tatgaggtag gggtggatgt tcctctccgg ttcctcgatg atggtaacag gccgctcctc
    11041 gaagtagagg gcgattatga tggcacagat attgatggtc ccgtccgaga ccatcgacgc
    11101 cgggaggtat ttttccctgt tatagacttc ttttaacttt aaaaacatcg acatgtccat
    11161 gaacttttcg acttccacgt cgtcgacgaa ggggaggact tcgtggagaa gccgggaaaa
    11221 caggttcctg cgttccgggt cgtcgatgat ctttttgatc acgatggcaa gattgcttcc
    11281 atccttttcg aggtcggttt ttcccatgat agggactgcc cttttgagga gccgggggtc
    11341 gaagtcgtag accttcattc cgcggaagat ccactcgagc gatggaacgc cggggatgaa
    11401 gagggggacc gtcatgatca gcttcttcct gtcagcttct gtcgtccgga acgagaaggg
    11461 aaggagttcc tcattgcgca gttcgaggcc gtccggggga gtgatggtgt aatggataac
    11521 ccgcccctcc cgtgcaaggc gaatcgtccc gatcccggtc tccttcttct cctgtccctc
    11581 cagccgcagg aactcaccgc tcaccgtgag agtatcggac gctatctcgt agttctcccc
    11641 cctttcgtga aaggagagtg aaaaagtata ggaaatctcc ccgggacgga agaagacggg
    11701 agagccggat ttcagggcca cgatgtcgga acgcctctcg tcaagcacat aatcgatccg
    11761 gaacgaaaag ggttcagatg ccccgatgag cgtgttgcgg aggtactcga ctccgccctg
    11821 gagcgaaact gcattggcca gaccgtactt ggcaatgtcc cgcaggaact tgatcacctg
    11881 gatgaagttt gacttgccgg atgcgtttga cccgatcacc acggtgaagt tatcgggctc
    11941 cacctcgagg tgcgaaaagc tcttgaagtt tctgacggtg agcttgcgga tcggcataag
    12001 agagagtgca tcaccggggc atatggtatt tgtgcccggg gatgacgatt acgtgtcagg
    12061 ggaaggggat accggcaact ccgaggtgtt ctgcaagttc cgcaatttcc ttccggaggt
    12121 ccctttccag ccggaaaagg ataacgaagt aaaagagtgc acccgaaagg acaatcccgg
    12181 cgagcaccgc gacgtgggtc gggaaaaata gccaccggag tatgaacacg aatcctccca
    12241 tgaggaggcc ggcgaccgcg atatgtccga ttgtggctat ctctgcacgc gcacccgtga
    12301 aacggaacag cgccagccgg gacaggcagg ctttgaagat gctgacgatg aggactgctg
    12361 ctgcagcccc ggtgatgcca agggaaggga ccatgatgat ctccaggagg acgagggatg
    12421 cgcaggagag ggcgttgatg agaaagacca ccttaaactt tccgaccgcg gagagcgcca
    12481 tgctgtcgag cacaaagata acagcgccta cctgggccag gaggaggagg gtgaatgcat
    12541 gcgttgcaac gataaacggc gacccgtaca ggaaatagag gaggcgttct ccgaggacga
    12601 gcccaccgca tacgacgggg accgcgagga cgagggagta ggaaagagcc ctctccaggg
    12661 catgacggat ggcagccgta tcgccctgtc catgccagct gcttaccctg ggaaagagtg
    12721 agatggagag tgatgttgcc acgaagaggg atagtgtggc aagctggagc ggtgtcctgt
    12781 agtatccgac accggttgga tccaggaagt acccgacaat gacagtgtct gcatacagtg
    12841 caaggaccgc tgcgagagac gaggaaaaac cccatgcggc atcggggagc agctgcctga
    12901 agtggcgcag gccgaatgca gccggcctga tacggaaaaa acgggcattg atcgcgactg
    12961 ccgcgagcag tccggcgata aatccgcctg ccattcctgc gacggcaaaa cccgtgccga
    13021 cagcgagaat ctggacggta acgcggatca ccgtgctgat gaactcacct gcctggagga
    13081 taccaacgct cccgtggcca tagatcccgg aggcaaggat gcctgatacc gaaccgattg
    13141 caagggctgc aacgagccag gggaggaggc cggcagaccg tgcatcgtgc atgaaaggcg
    13201 cagcaagaag gattattccg gctatggaga gacctgtcag gaacaacctt gccacagcct
    13261 gtgcagtgaa aaatgcaccc tcctgcccat ccctgctcat cttccttacc gcagcacccc
    13321 caaaaccccc gtcggacacg agggctgcaa tgctgtaata ggcaagaaac agatagtatg
    13381 ctcccagtac ccctgccccg gcgacgtggg caatatagac agtcgagagg tagccgactg
    13441 ccgtgatacc tgtgcttgta aggagggaca ggagtgcgtg gcgacggacg gcttcgatac
    13501 cgaggagccg ccgcaggaga gacgcaggaa cgctcacgtg caatcacttg aatctcccag
    13561 gagaaatagg cggtgcccgg tatccccggc acttgaccga cgtttctgcc cgatcgaaag
    13621 ggtgttggtt tacgggagcg cataccctaa agacgcaccc atgcagggga gtgaggagac
    13681 cacggagggg gagaggggag acaacagaat ccgctctccc attatccggg cacgggatct
    13741 tgtcaagaac tacgggaatg tccgtgcggt ggacaccatc agtttcgagg tcatgcctgg
    13801 agaggtcttc ggtttcctcg gaccgaatgg tgccggaaag accaccacaa tgaggatgat
    13861 ccagtgcgtt tcacccccga cagcagggtt cctctcggtt tttgggctgg acgtgaagga
    13921 ccacccggcc gggatcaaga gatggcttgg cgttgtcccc caggagacga accttgaccc
    13981 ggatttttca tgtcgtgaaa acctgcttgt ctatgcccgg tacttcgata tccctgcacg
    14041 ggaggcacaa aagagggcag acgaactcct cgctttcatg cagctgaccg agaaagccga
    14101 tgtcccgatc gatgggctgt cgggcgggat gaagaggagg ctcatccttg cccgggcgct
    14161 catcaataat ccccggctcc tcatcctcga cgagccgacc atcggtcttg acccccaggc
    14221 ccgccacatg atgtgggaga agctgaaggc tctccaggcc atgggaaaca ccattattct
    14281 caccacccat tacctcgagg aggccgagag gctctgcgac cggctggtca tcatggacgc
    14341 tggcagggtc cttgtcgagg gcaggcccgc cgacctcgtc aggaggtata ccggggacga
    14401 gatcgtggag tcagagaaca gcccgcaggt actggcctgc ctgcaggaaa tgggatgccg
    14461 ctacgaggtc cacggggaca tggtccaggc tttttccgac cagccgaggg ttcttgcgag
    14521 gcgcatcctc gagacctgca acccgggccg cgtcttcgtc cgcaggggaa ctctcgagga
    14581 tgttttcctc accctcacag ggagggagct ccgggaatga ggcgattttt tcccatgccg
    14641 acgtggttgg cgtggaaggt atggcagagg aacagggatg tctttttcaa gacgtacctc
    14701 gtgaatttcc tacctccgtt cgtcgaacct gtcctgtacc tccttgccct gggatacggc
    14761 ctcggcctgt tcgtgggcga gatcgatggc gtgccctatg tgtctttcat agctccggcc
    14821 ctgcttgcca tctccatgat gaactcatct ttcttcgagt gtacctactc ctcgtttgtc
    14881 cggatgtatt accagaaggc gtacgatgcc atggttgcaa cacccctctc gatagaggac
    14941 gtgattgccg gcgagctcct gtggggtgcg acccggagcc tgatctatac aacggcaatg
    15001 ctcgtcgtgc tcatagcgtt cggggttgtc gcccttccct cgtccctcct cgtgattccc
    15061 ttttcattcc ttgcagggct ccttttctcc ggcattgcca tgtgctttac agccatttcc
    15121 ccctcgatcg ataccctcaa ctaccctgcc ttcctcttca tcacgccgat gttcctcttt
    15181 tcggggactt tcttccccct ttcggttttg cccgggccga tccaggtctt tgcgatggca
    15241 atcctccccc tcgcccaggt ggtaacggtg tcccggtcgt tcaccctggc atccgtctcg
    15301 ctgcctctgt tcctgtacag cattgcgtgg atcgcggttg tttgcacggt ccttttcttc
    15361 gtctcgatct acctgatgag aaggcggctt gttgtctagg gatccggggg gagaaagcct
    15421 gtcgttttag cgattgccat ccacgaaaac cgggtaagga tatcctacct cccgcgtcgg
    15481 cagtctgttc tcccggagag atcctgcagc aagggcagac ccggtcagga caatgtttct
    15541 catcccccgg aacaaaacga tcctgttacg gtgtgatcca tggatctctg gttcatcgtc
    15601 ggaggcattg ccgccatgct gacaacgttt gggttcgtcc cccagatcca caagatgatc
    15661 cggacacggt ctgttgatga tgtcagtccc ctgacattcg tccagttcat ggcaggagta
    15721 agcctctggg ccctctacgg tgcacacatc ggtgacgtga tcgtcctgct tgcaaacatt
    15781 gtcacgttcg ggaccctcat cgttgccgtc tccctctact tttatctgcg accccggaag
    15841 gatggtgatt agaagaccgc atgcgaactg aaagcgaaag gtcccggcaa ttccgggaca
    15901 aaaaagatcc gcatgtgcag ggagggagag aggaagatat tcgcctctcc ctcatagggt
    15961 atgccatccg ggcccccagt caccggaact cccagccctg gaaagtcgcc ctcccggggg
    16021 catcgaggat tgttttatcc atcgatcatt cccgggttgc aggtgcgctg gatccttccg
    16081 gccgacaggc attcctctcc tgcggggcat tcctcgagaa cctcgacatt gctgcccggg
    16141 catcgggtta ccgtgccgac atcgaccttt tcccggcggg atggccggat cccgtcaagc
    16201 cactccggga tcccgtggcc agcatcgatc tcgaaaggga cgcaagaatc cagccggatc
    16261 ccctctttca tgcgatccct gtccggcaaa ccaaccggcg tccctattct gacaggccag
    16321 tccctctctc cgttgccggc gagcttggag cagccgggga tagcgagctg gtcccgttcg
    16381 ggtttacaaa cgacaggaac ctgatccggg agatacggga cctggtcgtg gatgcgcttg
    16441 cccgggaact ctccaacagg gaaagattca gggaatattg cgattacttc cggttcacgg
    16501 atgcagaggc cgcccagtcc ggggacgggt acgggtttgc acagtccggg tatgggaaga
    16561 ttacacgatt tttcaccggt gcgttcctct tttcccggga atctgttctt cgcaacccgg
    16621 aggcattccg gcggagagcc gtatccgatc tggggaagat aatggagaaa tgcggcggga
    16681 tcgggtggct ctccacgaag ggtgacttcc gcatcgacca ggtgagggca ggaagggcct
    16741 ttgagaggat acacctcaga gccagttccc tctcccttgc cctccagccg gtcgcaagcc
    16801 cggtggccgg ctacggggag atggaagagg tcagggccgg gctctccgaa cttctggcaa
    16861 ttcccgggac acacacaatc caggtgctct ttcgcaccgg gtacgcaaag cgggtcccgc
    16921 agactccgcg gaggaatatt tccgatttca tcgtttcctg accgggccct tcccagtcag
    16981 cccgggaaag gcatggagtg cagtaccagt gccaggaaga gaacggctgc gccgcaggca
    17041 gcgaggggga gcgtgtaggc aagggagatt tccctgatgg ttgcatccgt ggtgcggtgc
    17101 aggagccaga agaaggggtc ggtcagccag gagacgatgc atactccggc agcaaccgag
    17161 aggatcaggg gcaggggtgc gaggacactg gcaagggcag ttcctgccat gacctgggag
    17221 gcgattaccg ctgttgccac ccgggagccg agtgccgcct ggatgatcgc cgtaaatgca
    17281 aagggtatca ggacagcagg gagcgtcccg ctcactgcgg ggaagaccgc acctgcaaat
    17341 ccactttcca ggataacgtt tcccagtgct cccgcaccgc agatatcgaa catgatcagg
    17401 cctgcgtgca tcgtcccttt tttaagacct gtcgaacgcg cctctgcggg cgcaaggagg
    17461 agggcggttg ccagcccggc gagcattatt gcctgaatca tcgattcgtg cgagagggag
    17521 aagacgaaga gacagagagg tatggagacc acgatggcga tgaaaggagc ccatgcccga
    17581 agggaagata acacgtccga tccacctgca gcaggggagg aggctgcaat cccgcccttt
    17641 ccacctgaaa ttttccggaa gaggaggaca agtcctgcaa ggagtgccag ggagagggga
    17701 atggcaacga ggtcgtagag gaggggagac agacccgacc cgaatccgag gaggagaggg
    17761 atgatgacgg gtgttggaaa aacgagcgta taagagacaa cgcttcctgc ggcggtgagg
    17821 aagaggagca tgttcttctg gtggcggtcg cttcctgtcc gaccgataac gggcgcaagt
    17881 atgacgaaag cggtgatgca gcaggtcgtc aggagggaga aaacataccc tgcaatcgct
    17941 gcaaggctcc agctcccggg aaacccggtg cggaggtctg cgaccattct ctccaggtgt
    18001 ccctgttccc ggagtgtcag ggcgatgaca gccccggaga agatgatgat cgcaaagagt
    18061 gcaaagacgc gtcccagccc ggcaatgact gccccgagca cggtcccaaa gtccattccc
    18121 gcgcccatgc cgaagatgat tgccccggcg aggagcgaga gaaaaggcgg agtttttgcg
    18181 tatatgctca ggaaggcaag gaagagaagg acgaggagaa agaggacaag gagtgacatc
    18241 atccggacct tgcggggatg cgcccgatca gcggcgtatc tcgaacccct gccacgtttc
    18301 cgtgacctca ccggaccagg taagagagat gtccgcgatc ctgattaagg ggtcaccttc
    18361 tgcccggata tcctccagga attgttcaag cgtatcgctg tcccctgcag caacgatgct
    18421 cactgtcccg tccggattgt tcttcaccca gccccgtatg ttgcggcgga gtgcggcatc
    18481 cctgacgaaa taccggtagc cgaccccctg aacccgcccg gacacgacta ccctgatctc
    18541 tttcataacg gattgtcact cctgcaggaa cacgtgcgtg tcttttccgg atcacccggg
    18601 gctgtcccgt cctgcaaggc agccggtctg ccgatcacgg gatccgggac cacggcgaca
    18661 cctccccttt cttttccagt gccctgcacc ggggaaagta ggtctcccca aagacccagg
    18721 gcatgtagtt cctgcacatg tctggtttat ctgcgtgaat ggaacaggtg taacgggtct
    18781 ttccgacccg gcggaggaag ggacagacgg taggatattc accggtctcc gggtcacgca
    18841 tctccacagc cgtaatactc cctgttccgg gtgcatccag ttccgtgcag cgtatccagg
    18901 tcccgtctgc cctgcacgct ctgaaatggc ggagtatttc cgttcttccg tcaacaatcc
    18961 acgagtagat gttctcgggg gtgggggaga tcccgttccc gaagaccctg cagcagagcc
    19021 cgcactgcat gcaggaatcc tcgtcttcgt gatcctcgcc ggtgccggga gtgcccgcca
    19081 tactgacctg caggtatgct ctttttcccg gataatttta ccgtttcgtc cacgggatgg
    19141 tgccgtgccc ttgttttatt ggccagggcg tcataataac gtggcaatgg gattcgtttg
    19201 ccggcagtgc gggcagtgct gcatgcacat gggtgattac atcgtcatcg agcggcagac
    19261 tggtccgttt gagtttgatg cgtgttcggt ctcgaccggc accggcttcc tggcacgcgt
    19321 tgacgaagac aagcgcaaac tcttcctgga cagggaatgg atcgatcggc acccgtctgc
    19381 atgcccgttc ctccggccgg gaggggcctt gttcttctgc tgtatccatg agaccagccc
    19441 ggcccagtgc aaggcatacc ggtgcgtggt cttccgcatc cggtctcccg atggaaaacc
    19501 tgccgggttc atcacaggga ccctcgcact ccacacgaac gacccggctc tccgggaggc
    19561 gtggaaggaa gtcgaagagg tgatggggaa ggatccgggc cttgccgagc gggaaatacc
    19621 tgctgttctc gggaggaagg gatacatgtg tgactgacaa aaaaggaaaa agatccatgg
    19681 tatgatcttt ttaaagtggg aacctttccc ttcactcacg ttttcccctg catcgaccga
    19741 tgtgcagttg tcccccttta ataccgtgaa aaaagccggc ctctctgctg ccacgttctt
    19801 ttttggtcat caaaaggttc atgggagcgg agttacccta tcactcacgt atgggaagct
    19861 tcagcccgac agtcccccgg aatatccgga aacaccttgc tcccggtgaa ggcgtcgtcc
    19921 ttgttcttca cccctccgca tggagatata tcctgcatta cctgctgggg ttaattctcc
    19981 tcggtttcag tatcgtgctg cctgtttttg aagcaaaggc cgttgccgcc atttctggca
    20041 tcctgtacat tgcctacacg gaactcaggc gaaggaggat tgcatacgtt gtgaccacgc
    20101 acagaattat gaaggaggca cgcctgttct cgcgcaggag cagcacgtta ccgatgaacc
    20161 gcatcacgga tgtccacctc gaccagtcgt tcttcggtcg gctcttcaat tttggagacc
    20221 ttttcatcaa cacggctgga gaagggggat ttgaactcgt catggagaaa attcccggcc
    20281 cgggagatgt aaaggcgaca atagagtcac agctgctgga aacaagaaag aaatcatgag
    20341 atcagcgcta aggagaagac attccccgtg gatatcagga acggtgtgat tcacccaccc
    20401 ggtcccgaac cctttttttc ccgccggtca caatctctcc tccatggatg caatcgagga
    20461 attttttgag aaggatctct tcgcaaggga aaacgggata gaactcctgc atgtcgggaa
    20521 aggtgtggcc ggagtcagga tggccatccg ggaaaagcac ctcaacagtc atgggaccgt
    20581 ccacgggggt gccatcttct ctctcgcaga ctgtgcattt gcactggcct caaactccca
    20641 cggtgtgcct gcagccgcaa tcaatgctca tatctcctac atgaaagccg caaagtcggg
    20701 gagcctgcgt gcggaagcac gggaatttgc cctgaatccc cggcttgcaa cctacaccgt
    20761 cgaggtgacg gacgatgcag gtgaaaagat agcaatcttc cagggcatgg cttacaggaa
    20821 gacaccgcca cgcgggtaag atgaaggcag ggccgggctg gcgacattaa aaatggagag
    20881 gtgccccggg cctgaaaacc agtctggatg ggggcaaggg gatcgtatca cgccagcgat
    20941 tggtgcccgg ggactgtccc cttctggaat tgcatccgaa aaaaaggggg gggtcgtcat
    21001 ggtgtcatca cagtcacgca ccctgctatc atgagggggc ggtttcatca cccttcttcc
    21061 ttcgtgtctg cctgatcatg cggtctgggt actcttttgt gtcgttcagc ccttaccatg
    21121 ccgtgtcctg aacacagtgg tatttccggt ggatgccggg ttgttgactg ccgggctgtc
    21181 ggtattcccg gcttgagata ctccacgtgc cgggctgtcg cccctggccg gcttttccgg
    21241 cagcgcatcc ctgttctgtt gcaggaactg ctgcaggagt gtccttgcag tcccagtatc
    21301 accattcccg agtgcggccc tgatggcgct cacatcgaaa tccttttcct cgagtgagtc
    21361 gagcaaccgg nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ggccctgatg
    21481 gcgctcacat cgaaatcctt ttcctcgagt gagtcgagca accggtccat ccggtccatc
    21541 cgggtttggt tggtatccgg agcaggcagc gcatccctgt tctgttgcag gaactgctgc
    21601 aggagtgtcc ttgcagtccc agtatcacca ttcccgagtg cggccctgat ggcgctcaca
    21661 tcgaaatcct tttcctcgag tgagtcgagc aaccggtcca ttctctccga aagtcccgtt
    21721 ccatccaggc cgcaggcatc agggcgggcg tttagactcg ccgatggtat ggcctgcacc
    21781 ggaaaagtga cgaggagcag gaacccaacg agtattccca gtgtcagtgt atatgccagt
    21841 cttttcacat tctcctcctt tccaggtatc tttgcgtgtc agcaggtagc cgatacgtaa
    21901 aataaattta acatagtgtt atttataatt tactaataga caaattaaca atacatacgg
    21961 aatggaaaac aagccggagg gaaaaattat tcgtaggtga atatctcttc aatcgggacc
    22021 ccgaagaacc gggctatctt gaatgcaagt tcgagggacg ggtcatactt acccttctca
    22081 atggcaagga tggtctggcg ggttaccttc agctcctggg ccagtgcttc ctgggtaaga
    22141 tcccgcattg ccctgtagac ctttatttta ttcttcatcg gtgtcccact ccccgtacct
    22201 gcgggcataa tagatccgga atgcaatgta gaggaatgca atgcagcaga gcaggatcat
    22261 ctggaggatg ccgaaatatc caaggtaggg ctgatcgcgt ggaaaatcat gggggaactc
    22321 ccggggccgg ggtattccaa gcggggtcga aaagccgatt acagccgttc cgaggctgac
    22381 ggcaaagaag attatccaga agacctcgag tgtccggagc cctgccttct gcgtgatgag
    22441 ccgggaccgt tcgtcttccc tgatatccgt gaccatcagc cgggagacgt agacgagccc
    22501 cgcacccatg ataaaccctg ccattatgat aagcgggttg tgcagactga ccgagatcat
    22561 gaagagcccg acctcaacaa ggccgacaac cccgaccagt aaataaaacg tgttctgctt
    22621 cattgtaccc ccggtgtcat tagtatttaa caaatagttt tcttatcttt accggtggag
    22681 atatcttctt ccgtcatcct gaaaggtatt gaggagagga gacaagcttg tctgtacctg
    22741 ccatgacttt tccgtcatat ccgggacgcc tccttgggac agggacggat tctcttccat
    22801 caatagtctt ctccctcgtc ctcgctcctc tccttgcgtt tctctattat ttcctctgtg
    22861 tcctgatcct ccctctcgag aaggccctga tcctcggagg cctgatgatc ctctactaca
    22921 tccccccgtc cggcaaggaa tcgctcatcc cggtcgggat cgcccttggt attccatggt
    22981 ggctcatggc aacctcgctt gcactcctcg atgtcctcac gagccttttc atgatactca
    23041 atatcaggct tgccctccgg ctccctgtcc ttggtccctg gatatcaggt tttctgggta
    23101 agggcgatga attcatgaaa aaaaggccct ggattgcccg gtggtcagtc ctcggggttg
    23161 cattctttgt cttcctcccg ttccagggta ccggaggggt cggcgcgaca ctggtcggca
    23221 tgctcgtcgg cctgtcacct ttgcagatac tgcttgccgt tgcaatcggc gcctctgcag
    23281 agtgtctcct ttttgcagtc gggtccgaca tcatatggag gctcatactc gggaacatct
    23341 cggttggaat accggtcgcc ggggctgttc ttgcagcggt ggtcgtcgct tatgtccttc
    23401 tccgcaggtg gtacggggga gaagaggaat gatcccgggg ccagcgtccc gtgagagtaa
    23461 caaaaagttc ttgcggcccg ccgggcaacc ttatccccat catgggtagg ttgttcctgc
    23521 acaaccactg gtgcgaggcc gccgttcttt tcagaaggtc agggatacaa taccaggaga
    23581 ccattgcgcg ggacacgtgc ggggtttttg atgcagatat tctcctttga ctcactctcc
    23641 ggcctctcga gtgccgaagt ctcccggatc cgggaggtgg agggatataa cgagatcccg
    23701 tccgaccggc gccgcagccc tgctgcgatt atcctcggag tgttccggga accgatgttc
    23761 ctcctcctcg ttgccacggg agcaatctac ttcctgctcg gggacatcca ggaaggcttc
    23821 ctgatgcttt ccttcgtcat cgtgatcatc ggcatcacgg tataccagga gaacaagacg
    23881 gagaaggccc tcgagagcct ccggaacctc tcgagcccgc gggcgctcgt catcagggac
    23941 ggaaacctgg tccggatccc cgggagggag gtcgttaccg gtgattacct tgtcctctcc
    24001 gagggagacc gtgtcccggc agacggcgtc ctcctctatt cccagtcgct ctccgtcgac
    24061 gagtcgctgc tgaccgggga atcggtcccc gtgcgaaaaa cggcaggcag ggaggggttg
    24121 gagccctcac ccccgggtgg agacgatctt cccttcgttt actcgggcac tctcgttgtc
    24181 cagggacagg gacttgccag ggttaccgcg atcgggcaga agacggagat gggaaagatc
    24241 ggccgggccc tcatggcagt cgagagggag gacagtctcc tcaagaggga ggtcgccggt
    24301 atcgtcagga agattgccgt tgccgggatg tccctgtgtg ctgtcatagc cgtggtatac
    24361 gggctctccc acgcaagctg ggtggatggc cttcttgcgg ggattacgct cgcgatggca
    24421 atccttcccg aggagttccc cgttgtcctg acggtgtttc ttgcgctggg ggcatggagg
    24481 ctctcccggt accatgtgct cacgcgccag gttcccgccg tcgagacgct gggggcagca
    24541 acggtcctgt gcgtggacaa gacaggcacc ctcaccgaga acaggatgtc ggtgaaggca
    24601 ttctgctgta acggggaagt gacaccgttt gggtgcagga gcgacgaaac ggtccccgat
    24661 tcgtgccacg aacttgcaga atttgccatc ctggcatgca agaaggaccc gttcgacccg
    24721 atggagaagg ctctcctctc cctcgccgca ggggaatttg gaaagaccga gcatgtccat
    24781 gccagctggg acctcgtaca ggagtatccc ctctcccccg agctcatggc catgtccaac
    24841 gtctggcgtt cccgcgacgg gtcggagttc gtgatcgcgg ccaagggtgc tcctgaagcc
    24901 attgcggatc tctgccacct cgaacccggc cgccggacgg acctcgataa ccaggtggat
    24961 gccctggcct cgcagggctt gcgcattctc ggcgtcgcaa aggcatcatt ccgcccggca
    25021 gccctcccgg acaaccagca cgctttttcc ttcacgtttc tcgggctgat agggtttgca
    25081 gaccccgtcc gtccgggcgt ccgcgagggg gtcgcggagt gccgggctgc cgggatccgc
    25141 gtcgtcatga tcaccgggga ctaccctctc acggcccggt cggtgggtgc ggaaattggc
    25201 ctcccggacg ttgaccacat catcacgggt ccggaactcg accgtttaac ggacgcggaa
    25261 cttgaggaga gggggaggtt gacatcgatc tttgcccgcg tcgtcccggc ccagaaactc
    25321 cgcatcgtcc aggcgcacaa gaagcacggc gaggtggttg ccatgacggg ggacggcgtc
    25381 aacgatgcac cggccctccg ggcggcggat atcggcattg caatgggccg gagggggaca
    25441 gacgttgcga gggaatcggc gtcactcgtc ctgctcgatg acaatttcac atcaatcgtg
    25501 gccgccgtcc gcatggggag aaggatcttt gataacctca agaaggcgat ggcctatatc
    25561 ttctcgatcc atgtccccat cgcgggcatg tcccttgtcc ccgtgctcct ggccaccccg
    25621 ctcgtcctcc tcccggccca catcgtcttc ctcgagctga tcattgaccc cgcgtgttcc
    25681 attgtctttg agtccgagag ggaggaagag gatatcatga agaggccgcc gcggaagagg
    25741 gacgaaggca tcatttcggg aaaggcactg cagtttggcc tcttccaggg aggcgtggca
    25801 ttcgccggtg tgctcctcgt ctacctctgg gcactcctgt cggggatggg ggatgacgag
    25861 gcccggacac tcacgttcgt gaccgttgtt gcggcaaacc tcggcctcat cctcatcaac
    25921 aggtcgtgga ccctcccctt ctgggagaca ctcgggctgc caaacagggc gttctggata
    25981 gtcatttccg ggacactcct ctgcctggct ctcgtcattt cactcccccc gatgagggat
    26041 ctcttctctt ttgccccggt gtccgccacg gccctcttgg tcgcttcggc agcgggggtg
    26101 gcaagcgtgc tctggttcga ggtcttcaag ttctggaaga ggaagactgc gggtaacacc
    26161 gcgacaccgc cctgaacaga tgggggatat cccaggctcc cctttcggga aaaagcgggc
    26221 cagggtcacc ctttccggaa caggcgccgt ccgaacggac atctcccgaa ccggcacagg
    26281 agcgagacga cgatgagagt cccggcaccg atgaggacca tccctcctac ctgcatcagg
    26341 gtccccatcc acgggctccc ggggaggaga cggaggtctg caaggtcgat tccggaggcg
    26401 agccgtgcca gagttgtccc aaggaggatc gccggtatga catatttgca cagcgggtgg
    26461 acgattcccg cgaatgacct gccaatctcc ctgtccagga tctcccgtgg agcaaaccag
    26521 gaaaagctca cggcaagaat aacggccgcc agggggagcc cgagagtgcc gacggtttcg
    26581 tccatgaagt cgaggatttt gacgcccccg acggtccagt tcgccgcgct gtaactgagg
    26641 gatgagggca ggcctatggc caccatgaca agtccgagga ggagcgaagt cttttcccgg
    26701 gaccatgaca ctgcctcgcg aagcgaggac actcccacct cgagcatgga gacagccgat
    26761 gtgatcgccg caaagaagag gacgaggaaa aacgaaacgg caaagataac tccgcccggc
    26821 atcagggcaa atgccttcgg gagggttgag aaggcgagtt ctgcccctgc cgctggttca
    26881 agcccgaacg tgaagacgag gggaaagatg acgatccctg cgaggagggc gacgccaagg
    26941 tccgcgaggg tgatgacaag ggcagaccgg gggattggta tgcctttttc catgtatgcc
    27001 ccgtaggtga ggagaatccc ggtcccgaca gagagggaaa agaatgcctg cccgaacgca
    27061 gcactccaga cgagaggatc aaagagcacg gaaaagtcgg gggaaaacag gaacaccgtg
    27121 ccttccagga atcctggaag ggttgtgacg tagagggcca tcacgatcag gattgccacc
    27181 gataccggga tgaggatgac cgaaacgcgt tctattccct tccgcacgcc ccgcgaaacg
    27241 acaccggttg tgacagcggc ggaaaaaagg aagaagaaca ccggcatgtc tgatgccgtg
    27301 aaatctgcaa acgttatgct cacccctgcc agcgagaaaa gtgcgtatgc cgctgtccag
    27361 ccggtgatga cgaggtagta gcagaggaca agaaatatcg ttgcgcacag gaaccacccg
    27421 gcaatgcgga aagatggcct gacagcccgg aacgcaccga caacagtccc atggaagctc
    27481 cgacccatcg cgagttcgaa aaccatcagg ggaaatgcac atgcaaagac cgcgatgaag
    27541 taggggatga ggtaggctcc gccgccgttc tggccaacga ccgatgaaaa acgccagatg
    27601 tttccgatgc caaccgcgga gccgatagca gcaaggataa acccggcccg tgatgaccat
    27661 tgttcccctt cagcaggcgt tgtcctccct cccggatagg gaaatcgttt tcccccggct
    27721 cctccggtcc ctgtcagacc ggataaacaa cttgaaaagt tccatgacca cgacgacagt
    27781 gcctgcgatg caaaggcata ccagccattg ttcgagggtg acagggacaa gtccgaggat
    27841 ttcctgcatg agggggacat gcagggagat gatgtgcaga ccctgcatga ggatcactcc
    27901 cccgatgagg aaatagttgt tggggatagg aacgcggaat accgattgat actcggacct
    27961 gcagttgaaa acatggaaat tttcgaagag aaccatgagg aggaggagca ggttccttgc
    28021 aacggtctcc tccgttccgc tcgcattgaa ccaccagaat gccaaaaatg ccaccagtcc
    28081 gattgtcaga cccgaaagca gcgtctcccg gaccatgaga ccgttgaaaa tcccttcacc
    28141 ggggggccgt ggcttccttg tcatggcgtc cttttcaccg gcttcgaagg cgagggccac
    28201 tccctggata ccattcgtca cgagattcag ccacaaaagc tggactgcga ggaggggaat
    28261 ggggaggccc gcgaggaggg cgaggatgaa gaggacgact tctgaaaggc ccgtcgagat
    28321 gagaaggtag gtgaccttcc ggatgttgtc ataggcaaac cgcccctcct cgacgcctgc
    28381 gactattgag gagaagttat cgtccgtcac gatcatcgag gcagtatcct ttgccacgtc
    28441 cgtccccgaa cccatggcga caccgatgtt tgcgcgccgg agcgcaggcg catcgttgac
    28501 gccatccccc gtaaccgcga caaagtgacc ccgccggacg agggcgtcca cgatctccat
    28561 cttctggagc ggcgtgaccc gggcaaagac ccgcgttctg tcgatgactt ccccgtaggc
    28621 ggggagcatc ggatcaccca tggcggcaag atccttaccg gtcaggacct ccccgaagtc
    28681 ctttgcaatg tccagatcgc gggcgatagc aaaggctgtg cgggggtggt cccccgtgat
    28741 catgacaacg tcgattcccg ctccgtgggc gaccctgaca gcgtctttga cgtctggccg
    28801 gaggggatcg atgaacccga cgagaccgtt cagcgtgagt tcgggtgctg ttttttccag
    28861 tccgggatcc ggtcccggtg cggagcggag agccccttcg gcgaccgcga ggatccgaaa
    28921 acccttctcc atcatggtct ccatgtgcga cccgaccagg agaggatcga aaggcacggt
    28981 tcctgccggg gttgccattg ccctgcagta cgggaggaga gcctcgacgg cacccttgac
    29041 agcaattttc acggggcccg ccggatcctc tccctcgcgg taatagaccg cggcgtacat
    29101 cctttccgac tcaaaaggca catgagcgac attttcgatg ccattcctga catcgtcggg
    29161 aacgagacct gccttgtatc ccagggcgag gagtgcgacg tccattgcat ccccgctgtg
    29221 gacccaggtc ccgtcttccc tgtacagcgt cccctcgttg cagatgaccg caactttggc
    29281 gaggccccgg acggcaccgg caacctgttc agggatttct tcccccgcga tccggaaagt
    29341 tccctccccc ggatcgtaac cggcaccagt cacctcgact atcgtgcccg gggggataaa
    29401 gactgcctgt gcggtctgct ggttgacggt cagtgtccct gtcttgtctg ttgcaattgt
    29461 ggtgcagctc cccaggcttt ccacggcagc aagtttcctc acgatgacgt tcctgcgtgc
    29521 catgcgggat gccgcgatgg agagggcaac ggtgatagca acgggcagcc cctccgggat
    29581 cgcggagacg acgagggcaa cggcaaggaa gaagacctcg acgggaggca cgccctggga
    29641 gagtgcagca atagccatca cgatgctggc cgagacaatg agtgcgccta cgttccggga
    29701 gaaaatctcc atgcggatga ggagaggggg ttttgcagac tctgtttccg agacggcctc
    29761 ggctatcagc ccaacctcgg tgcgggtccc tgtccccgtg acgatgccgc accctctgcc
    29821 ggagacgacc gtgctcccgg caaatgccat gttaaagcgg tcactcaccg gtgccttctc
    29881 ttccgtgatg cccaccgttt tttggaccgc gaccgactcg ccggtgagaa gggattcatc
    29941 aatggacagg tttgccgtat gcaggagcct catgtcagcc gggactttca tgccggactc
    30001 gaggaggacg acgtcgccga ttacgaggtc ttcggcagga atattctgcc aggcaccgtc
    30061 ccgtttgacg cgggccgtga cacggaggag gctttggagc ttctgagcgc tctgctctgc
    30121 cttccactcc tggatcgtcc cgatcgcggc gttgatgcag acaaccagaa agatgaaggc
    30181 agcgtccctg gcgtccccga tcaggataga gatgactccc gccgcaagaa ggatgtagat
    30241 gagggggctc ttgaactggt ggatgatgac ctggagaaga ccgggagcct ttcgggatgg
    30301 aagggtgttt ttcccatact gtgcgagacg gtggagtgcc tcctgccggg tgagcccccc
    30361 ggatcctgaa cggaggatct catagacttt gccgatcggg agagcatgcc aggggacccc
    30421 gtggtggggg atggtcccgg ggatcatacc agtttgggaa caagcggaaa attagtcccg
    30481 gaattgttct ttccgggcaa tcaccatctc gcaaaacccg tcacccctgc agcgggccat
    30541 ggagaccccg acagagaact ccgggttgag ggcttctact acagatttga cgtaggcgct
    30601 gcagatggcg tggatctcgg ccggagggat gcagggggca ctctcttccc ggaacattgc
    30661 gcactctgcg agccggatca caccctcttc cgggaagccc tcgatgtagc gggtttcgaa
    30721 agcacgtcca aagaggataa cggagacagt cccgagcgtc gccacaaggt cagcggcatt
    30781 gtcccttttc atggagttgc catcggcaat gcgacgggcc tcttccccga ggagggaaaa
    30841 gagccgctga ctgtcgggcg atcctccggg ccgtgctgcc gtcctgccca gttcaagaac
    30901 aagccgggtg agaacgtggg aggcaagtgc ccaccgcgtg gagggcggaa tttcgcgcag
    30961 gtgtgtcatc gtcctctccc ggggcattta tgaatctcca ttcctctcat tgtcttacaa
    31021 tggccggtgg ggaataaagc atttcccgtg tagggaacat gggaacaccg gaagaggtca
    31081 cagtctcaag tctcattccc ccccactgcc ggagcatcat attattttcc cgcggagcga
    31141 gatatccggt attctgaaac tgcctgtgca gcaacggaca ccatctgcac cggtcccggg
    31201 agggcatgat ggatctctca atcctcaccg atatcctcat catattcggg ctttccctca
    31261 tcgtcggcct cgtattcaac cgtctccgga tccctccgat gatcgggtac atcgtagccg
    31321 gggtcatcgc ggggccatcc ctcctctccc ttgtccagag ccccgcacag gtcgatatcc
    31381 ttgcggagat cgggatcatc ctcctgctct tttcaatcgg actcgagttc tccttccggc
    31441 agttgtggga gatcaggagc ctcgtccttt ccggcgggtg catccaggtc gccctcgcca
    31501 cggtccttgc gacggctgtt gccctcgcca tcggtcgtcc ctggaacgag gcagtcctcc
    31561 tcggttttgt cgtctccctc tcgagtactg ccgtcgtcct caagatcctg cacgaccggg
    31621 gtgaactgga ttccctgcat ggaaagctga cgctgggcat cctcatcttt caggacctcg
    31681 tcgccatccc gatgctcatg gcagtcccgt tcctcgccgg ggtggcaggc ggcaccggag
    31741 atccgctcct tgtcgtcatc ctcaaggatt tcatcttcgt tgcaatcctt gttgcaaccg
    31801 cgaagtgggt catgccggca gtcctgttcc agatcgcgag gaccagaaac aacgagctct
    31861 tcctgctttt cgtcgtctgc atctgcttcg ggattgctgc ccttgcctcc tttgcaggcc
    31921 tttcccttgc aatgggggca ctccttgcgg gcctgctcat ctcgcagtcc gagttcagcc
    31981 accaggcgat cagcaggata gtcccgtttc gcgacatctt caccgcgttc ttctttgtct
    32041 ccatcgggat gctcctcgat gtcggcttca ttctcgaccg ccccggactc atcatcgtgt
    32101 tcctcatcgt cgtccttgca atcaagttca ttgcaggctc gctggccccg ttcgtgctcg
    32161 ggtaccagct ccggaccatc atcctgacgg gcatcgcgct catgcaggtc ggggaattct
    32221 ccttcatcat cacgaagagt gcgctcgaca tcgggctcct ctcgcgggat gcctaccagg
    32281 tcttcctcgt ggtcgccctg atctccatgg cagcaacccc cttcctcatc ttatccggac
    32341 agccccttgc atcgtttgtc tgttccagca ggttcttcca gaaggtcctg ccggggcggt
    32401 gccagtgggt tgcaacggaa aagaaggtcg caagatccgg gcacctcgtg atcatcgggt
    32461 acggggtcaa cggcaggaac ctggcacggg cagcccgcat cggcggaatc ccccacgtca
    32521 tcatcgacat gaacccggat tccgtccggc aggcacgaaa agagggagaa gcaatcatct
    32581 acggtgatgc gacaacggag ggtgtcctcg accatgccgg catccggcag gcccggacgg
    32641 ccgttgttgc catcaacgac cctgttgcaa cgagaaggat cgtcgggctc tgccgtgaaa
    32701 tgaaccccgg gatcttcctc gtcgtccgga cccggtacat cgttgaagtc cctgtactcc
    32761 gggagatcgg cgccgacgag gtaatccccg aggagttcga gacctcgatc gcgatctttt
    32821 cgcgggtcat ggcagatttc gggataccgg acgagaccat atcgcgcctc gtccacgaga
    32881 tccgttccga gagctaccag ttcctccgga accctgcttc ttcgcccccg atacaggcac
    32941 tcgagatacc cggtatggag gtcaggatca ttcgcgttgc agaaggtgca cccatcgcgg
    33001 gcaggaccct tggagaagtt cttttgaaaa agaggtacgg cgtaactgtc cttggagtga
    33061 ggcgggatgg ggcaatcatc ccccatccgg atggcacctg cgagatcagg gcaggggacg
    33121 aggtaaccat caccgggacg aaggataaga ttgcgggtgc aatttttctc ttttctcccg
    33181 cgagtgactg accaggatca tacgcggacc atcacctgtc tctcacctca gcatcccctg
    33241 caggaagtgt ttttcccgga agaacgctta cctgataggg atggaaggga tcgttgccac
    33301 gcccgagttc caggtgagcc tcctcctctt tgcagcactg ggaggttacc tccttgcatc
    33361 gcggatcaac cagtccgcgg ttgtggggat catcctggtc gggctcctga ttggaccgag
    33421 tgtcctggac ctcgtcacgt ataacgagtt cgtcaggggc cttgcccacc tcggggctgt
    33481 cgtcctcctc ttcgtcatcg ggtttgagtt caagctcaag gacatcgtcc ggcctgccta
    33541 tgccttcatc gcactgatag gtgtcatcat cccatggctg ggagggtatg caaccgcgtt
    33601 atgggcgggg atggaatttc aaacggcact cttcgtgggg actgcactga ctgccacgag
    33661 tattgcaatc acggcaaacg ttctccagga gatgaacaag ctccagaccg acgccgcacg
    33721 ggcgatcatc ggggcggcgg tcatcgacga tgtcctcagc ctgattgccc ttgcgatcac
    33781 gggcgacgtg gtggcggggg cattccaccc gtccgttatc ttattcatcc tcctcaaggt
    33841 tgtcatattc ctcctcgtgg caggggctgt cgggatattc atcgtgagca ggtttttggt
    33901 caggctggac aacaccccct tcgtggcccg ctaccctgaa ttcatcttca tcttcgcgat
    33961 gacctttgcc ttcctctatg ccatgatcgc agagctcgtg ggcctttctg ccatcgtcgg
    34021 cgccttcatc gccgggatat cattcgagag actgacactg cgcaagagcc tcgatgtcaa
    34081 ggagggtgcc gagttcctca agataatctt cgccgcgata tttttcgtct ccctcggcgt
    34141 cgttgccgat ttcaagaccc tgacgcccga tattttacct ttccttgtcg tcctgacaat
    34201 cgtggccatc gtgacgaagg tcgtcgggtg tgcaattcct gcccggatcg ccgggatatg
    34261 cagaaaagat tcgctcatca tcgggtttgg catggccccc cggggggagg tggcgatgat
    34321 cgtcgccctg attggtcttg aacaggggta tatcgggcag gcggtcttcg tggcaatcat
    34381 cgtgatgagc ctgctgacaa cgttaattac accgataatt taccggaact ggttcttcaa
    34441 agacgagaac tgcggcccgg tccagcagat ttaggaaaat tcccgtccat ttttatcagc
    34501 tttttgcgag ggattcctca ccaaaagaaa aacgtcctgc ccctcccctc acaccagcgg
    34561 gaagagcgac cttgtcattt catgggccgg gcatgtgatt ggccccctgt ttcataagag
    34621 cttcgtctct tcggtgggcc gtggaacttt cactacgagg acacggaaga ccgcgttgct
    34681 ctcgttgatc caccggtggg gaatccttgc cgggctctcc acgagagtcc cttccccgac
    34741 ggtctccctc tcatcaccga tctcgacagt ccccttcccc tgcaggacat agaagaaaac
    34801 atcgacgggc gtgatgtgcc gcttgagggc ttctcccggc cggagcgtga tgaccactgc
    34861 gactgcgtgc tccgtgtcat acacctttcg tgcatcaacg tggtgggggt tgggctgtgg
    34921 cgtgacgtcg tctaacctcg taatcttcat gaggacttct ccttttcgag gaatgaaccc
    34981 cccgctttat aaagtttgct ggttaccaca ctttcttggg ggagaggaac caacacatcc
    35041 gggctcaatc ccggtctacc accacattga tgtggggggg ctgatagatt gacataccgg
    35101 gtgaaaacat gccgggacca ggtcccaata caatccagat ggtgggaatt gcctacggaa
    35161 tcctcttcgt gatcgccggt gccctcctct ggcgatcggg aagattttcc cggactgtca
    35221 ggtatgcatt gctcctcgtg accattctcc ttgggtttgc gatattttct cccatgcttc
    35281 cgtacatgtt cggtgaactt gttgcacgtg cagattcgcg ggtgggtgcc acactccttg
    35341 gcgcaaccct cgggatggtc ctctttttcc tcctgacgtt cctcttcggg agacatttct
    35401 gtggctacct ctgccctgtc ggggccgtcc aggaggtcgc atacgtcgtg ccggtaccaa
    35461 aggtccggct tccctggaag atacttcccg tgattgtcag ggcagttgta ttcctgctca
    35521 tcatcggtgc cgggcttgtt tattccatct ccatcctctc ttacgtgggg ataaggcagt
    35581 tctttacgct caccctctct gccggtttcc tcgttttttc gtgcctgctc atcatctcgg
    35641 tcttcttcta ccgcccgttc tgccggttca tctgtcccct cggcgccatt ttccatgtct
    35701 ttgcaatacc ttcccgctgg aagatacgcc ggaccgatgc ctgcatcgag tgcgggaagt
    35761 gcgagaatgc ctgcccgacg agcgaggcag gacgggagga caccaagggt gagtgttacc
    35821 tctgcgggcg gtgcatggac acgtgccctg tcaaaggcac actgatatat gcgggaaaga
    35881 cgagtaagga aggtacggag aagtgactga atcaatggca agagagagca ggaaagacct
    35941 gcgggggcag gtgtttgcct taaaggacct cgtcgagtac cagccgggga cggttgcgag
    36001 cagaatgatc atcaacaaca aggccgggag catcacggtc ttttcctttg acaaggacga
    36061 gggactctcg gagcatacgg caccctacga tgccgtggtc accatcctcg acggggaggc
    36121 ggaagtctgg gtcggtggcg agacccatgc catgaaggag ggccagacca tcatctttcc
    36181 tgcaaacgtg ccccacgccc tttctgcaac gacgcgtttc aagatggcac tgacgatgat
    36241 ccggggatcc gaggatgagt gaagggggtg aggggaagta ctgcaccatc tgtggtggta
    36301 ttccccccga agagatcaag atcaggaaga tcctgatcga tgggaaggag acgggaatcg
    36361 acaagctgga tttcatcctt gaggaggttt ttcggctgaa ctgtcctacg gaccaggaga
    36421 tcgtggcgga gatcctcagg agggtcaggg tttttaatta tgtcccgacc agggtaacag
    36481 aaaagtacgg ggaagccctt ctcgaggagt acaggcgctt cgtgcgggac cgtgaaatac
    36541 ccggacagat aacctgaaat tctctttttt tgtttttttt gtctggaggg ttttgatcaa
    36601 gtttttttca ttggtgaaag tcggttattc attttatacc ccggcgggaa tctcccggta
    36661 tccatgggaa gacagaacct ttctctcttt aataaaaccc ggtgtgttcc atgcaggaag
    36721 tatttatggt gggatgccgt tattcctcct catgacagaa gaactgcccg gcgctatcct
    36781 gcagcgggat ggcaaatcat acgcaatcgt tccccggacc ccctcgggta tcgtgacacc
    36841 cgaagagctc gagcgaatag ccagggtagc aaggaaatac cgtatcccgg ttatcaagat
    36901 gacatcgggc cagcggatgg tccttgtcgg tctcaacaag gatgatatcc catcggtatg
    36961 gagagacctg ggaatggacg tagggcaggc cacggcgccc tgcgttcact atgtgcaggc
    37021 ctgtccggga accgagacct gcaggttcgg ggtgcaggat tcccttggcc ttgggcttgc
    37081 aatcgagaag atgtacaagg atctctccct gcctgcaaag gtcaagatcg gggtctcagg
    37141 gtgtccccgg tgttgtggcg agagccatgt ccgggacatc gggatattcg ggacaccgaa
    37201 ggggtggaca atcgtttttg ggggaaacag tgccacgaga ccaaggatag gggatgtcgt
    37261 tgcaaaggac ctctccgcgg aggatgccat cgacctctcc cggaggcttc ttgagtatta
    37321 ccgtgaccat ggaaaaccac gggaaagaac cgcccggttc gtggaaagaa ttggattcga
    37381 ggcaatccgg agggatgtgc tcgcctacac cccgtacatc ccgatgggga agtgatggac
    37441 cggtcctgca tagtacaccc cccccatcat tttcatccgg cccgttttgc cataacaaat
    37501 gaccacgatg atgttttggt tcgtatgccc gcaggaagca tatttcgccc ctctcaacgg
    37561 ttatcctcgc caattggagc aaaatgatgt ggggaaagaa gtatataaaa tcttaaatca
    37621 gggtgtaact caataaacca gcaggttctt ttaaaggaga gataccatga acacatgttt
    37681 catttaccat tcgtactcgg gtattacgag aaagcttgtc gaaaaggtgc gggcagcctg
    37741 cgggggagat gcaatcgagg tcacaccacg ccagagatac aatgccctga ccgcgtatac
    37801 actggggtgc atgagggccc ggaacgggca atgcgatcct atcgatccgg agatcatcga
    37861 tgtttcaggg tatgatctca tcgtcatcgg gaccccggta tgggcatttc gggcaactcc
    37921 cgccgtgaat gcagcgattg cttcattgag aggcgccgaa gggaagaaag ccgtgctctt
    37981 tgcaacctgc gggggaacac ccggtgagac aattccccgg ttgagagacg cacttgccgg
    38041 gaagggagca gaggttatcg gagagatggt ctttacaaag aaagatacag gggatccgga
    38101 gaagattgat gccctgatca ggatggtcat ggatgcagca gggacatcct gaaatggcga
    38161 gggataaaaa ttttcaaaat cttgagaaaa ggggattctt cagccctgtc ccggtgtgag
    38221 caccgtgaag agcttcttgc accgggaaca cctcccgtcc cgcgattcct tgtagaaggc
    38281 cttgggcatg ttgaagacga tcgaattttc cttggaacag ctggggcacg tgaagcggat
    38341 gacgtatccg gaccgtgtcc caatgacggt ctctctgact gaactctttg ccatatttac
    38401 ctccgggaaa aatccctgac cacttgcgta ttcttcagtc tgtccccgca ggagagcaaa
    38461 cctgcaggca ttccccagga cgggtcccat gcacgcgaag aaagagacgg gcaggatcgc
    38521 gtttcaaacg gggaacttat aatatatggg acgtccgggg ttatgagacc ttgcatcatc
    38581 gcgcatttct gcacgaacag gacaatgagg acaggcagga cccttcaccc attctccatt
    38641 cccgggaaaa gagcagagac tgattcggaa gaagggggcg ggtaaaaacg gcgtggaact
    38701 ggtgttagac gaatcaacga aaaattggga tttagagccg tggccgccgg tggttcggga
    38761 ggcactccct gcagtagaca ggcctgccct cggtcggctt gaacggtact tcgcactctt
    38821 taccacagtc tgaacagact acctttgtca tctcgcgggg gccgaagttc ctcggtccgc
    38881 caaaatttga tctatacatg gttttactca aacagttccg aaaaactgta ttataccatt
    38941 gagcctgcca gctgataaag gagtgcatcg ggctctttcc cgcacttcca cacggaacct
    39001 gtcgttccag cttttttaaa cttttcattt cgatatcgga gagtttttgg aagagatcac
    39061 ggggaggggg cggatgggat gacacctgct catcccgggg tgagcgcacc gggagtgcgg
    39121 gcaggagcca tctttattgc ccaccacccc cctcgtgaaa atgggagacg agacggagca
    39181 catgtcaacg caccgcttct tcatcgacca tcccataagg gccaagaagg tcaagctcgc
    39241 aaccgggtgt tgctgtgagc tgtgcggaag ctccctgccc ctggaaggcc tcgagataca
    39301 taccttttcc atcggcatgc agagtgttcc cccgcagccc gcggttctcg aggaacacct
    39361 ccttgtcctg tgtgcccggt gtcacgcgga catccacgag ttctccctgc ctgtttccga
    39421 gcaggaatgg ctcgtccgga tgagggacgg tcacaaaaag gaggagatat gttcaattct
    39481 tggctatgtg ccgcgcaggt atacgccgcc ggaaagcgac atcgaggagg cgtaccggga
    39541 ggcctgctcc tcccggttcc ggttcggtgt ctaggcgttt tacgattttc ccggaaattc
    39601 gattgtctcg aggagcgaga gggtttcctg cgcccaatca acctgggcga tgcaggtcat
    39661 gatctcgttc cgggcagctg accggaggaa cggtttttcc acggcagtat ccggcagcgc
    39721 tgcaatcctg ttttcccgca tctctatctc ggcaatagag tcctcgcgac gcttgcggaa
    39781 cgcacggacc ttttccttca ggagatcggg cgggaggtga tacccaaaga gacacttgag
    39841 gaggacctcg gaatcatttt cttcgggtga ctgcaaccac cgctgcattt ccttctttcc
    39901 cttcccggtg attgtataca cgtccttttt ctgaccccga tctcccggtg ggtgcaactt
    39961 tgtcaccagt ccctcttctt cgagggtacg gagcgatgaa gagactgtct ttgggcctat
    40021 tttccaggag gggcagaaga aatcccttat ccatttcctg atctcgttcc cggtcatggg
    40081 tcgggtaccc aggactccga ggacgatgaa ccgtgcatgt gcgttctttg gcatctgtat
    40141 cacccgtctg ccctctttcc ttcgacatcc aatgggataa agggaggggg tcatagacga
    40201 attgttcccc ctgtctcgtg gcccgaaggt tttaccggtg ggaaaacctc tgccgggttt
    40261 cgtcgagaat gcgatccagg acagcgggag gaacctcgat gtctcccctt ttcccgagga
    40321 ccgcaaccca gctgttgagg ccggcagtga cactgtctgc accccacctg tccccgcacc
    40381 tctccatgat tgtccctgca aggcgatctt tatcgacgaa ccgcacgccc cagacctctt
    40441 cgattgtccc gagctgcgcc ctgacctgcg caaggagcaa ttcctgctcc gttccccgcg
    40501 tcttaggaat atttctgccc aagcctgttg ccggggaata ctcacctgcc agatcacgga
    40561 cagcgtccgt gtagagatcg aaagcccgct ttccgtggca cacgaaaatg accttctcta
    40621 tggagtccga ccgggagagg aacgacagga cagcccggac cgcgatgacg gttgcccggg
    40681 gaaggggaaa accgtaggca cccgtgctga ttgcagggaa agcaatcgtt ttgataccgt
    40741 ttgcctccgc gagttcaagg gaccgtgtgt agcaggatgc gagcaggtcg tcttcaccat
    40801 gcccccctcc ccgccagacg ggaccgacgg catggatgac gaagcgtgca ggcaggttgt
    40861 atcccgccgt gatctttgca tcccctgtct ggcatccccc cagccgccgg cactccccga
    40921 ggagaccggg gcctgccacc ctgtggattg ccccgtcgac accaccgcct cccagaagag
    40981 tctcgtttgc ggcattgacg atggcatcga cgtactgctc cgtgatgtcg ccctccacaa
    41041 cggtgaccct ttcacgaaga ggtctctgca tgtgtgggga attggacctc ttccacatat
    41101 ctttttcggg ccggtgcata gatacatctc ctttgaaagc acgagacatc tcgtaaggga
    41161 agggagaggt gcagtggagg gaaagcccgg gcttttggca ggagaccttc atggccagga
    41221 tctcgtggcc ctgacggaag aggaagtact atccgtactg gctacatcca agaacgggct
    41281 tcccctgcat gaggtggccc ggaggcagtc gcaatacggc ccaaacgaca tttcccgggt
    41341 gcacaaacgt tccgttatcc tccggttcct cgaccacttc cggaatgtcc tcgtcctcat
    41401 cctccttttt gccgcggtta tctcgttctt cgtcggggac tatccttcgg gcacgatcat
    41461 cgttgcaatc gtcattgcaa gtgtcgtgct tgatttctac caggagtaca gggcagggaa
    41521 cgcagccgaa ctcctccggc agaaaatcct cacccatgcg accgtagtcc gggaaggagc
    41581 tgaacacgag gtcccgctga cggatcttgt tcccggagac atcatccgcc tttctgccgg
    41641 ggacatcgtc ccggccgatg cccgtctcct ctccgggcgc gacctgttca tcaacgagtc
    41701 ctccctgacg ggggaaccgt tccccgtgga gaaacgtgca ggccctgttc ccacagggac
    41761 acccctgaca gaagcaaaaa actacgtatt cctcggaact tcggttgtca gcgggacggc
    41821 ggttgcggtc gtaacgctga cgggcatggc gaccgagttt ggaaggatag cccggacgct
    41881 ggtggcacgg ccccccgaga ccgggttcga gaagggactt tcccagtttt cctacctcat
    41941 gtcccgtttc atcttcattc tggtcatttt tgtcttcctc atcaatgccc tgttccgcca
    42001 cggtgccctt gaatccctcc tttttgcagt tgctctcgcc gtcggaatga ccccggaact
    42061 cctgccgatg atcctctccc tcaacctctc caagggagcc attgccatgg cagagaagaa
    42121 ggtgatcgtc cggcatctcg agtcgatcca gaacctgggg agcatggatg tcctgtgcac
    42181 cgacaagacc ggtacactca ccgagaaccg gatctccctt atcgagtacc tggacccgga
    42241 tggcgccccg agcgaaaaag tcctctacta tacgttcctg aacagctatt tccataccgg
    42301 cgtccaaaat cccctcgacg aggcggtcat ctcattccgc ccgctcgacg ccgggcagtt
    42361 ccggaaggtc gatgagatcc cgtttgactt cgtccgccgc cgcctctccc ttgtggtcga
    42421 tgatgggaac gagaggctcc ttatcacgaa gggtgcaccc gaagaagtcc tctcgatctg
    42481 tacatcgatc gaacgcggtg aaaagacaga tgccctctct cccggcgatc gggaatctgt
    42541 cattgccctc taccatgaga agagcaggaa aggtttccgg acccttgcgg tctgtaccag
    42601 gaagcttccc agagacaggg cggtcttttc ccccgaagac gagcgggaaa tgaccctcct
    42661 tggtctcgtc acgttccttg acccgcccaa ggagagtgcg ggggaatcgg tccgggccct
    42721 tgctgaatcg gggatcgatc tcaagattct caccggcgac aacgaactgg tcacgcggag
    42781 ggttgcctcg ctcatcggtc tcgaggtcag gggcgtcctc accggcaggg agatcgacca
    42841 gatggacagg gaggcgctct cccgcgtcgt cgaggaggtc acgctcttct gccgcctcac
    42901 gccggtccag aagaaccgcg tccagaatgc gttacggaag aacggtcacg ttgtagggtt
    42961 catgggcgac gggattaatg atgctcctgc catccgggag gcagacgtcg ggatatcagt
    43021 ccggaacgcg gtggacatcg cgagggaatc cgccgacatc atcctgctcg aaaacgatct
    43081 ccgcgtcctg catgacggtg tccgggaagg gagaaaaacc tttgcaaata ccctgaaata
    43141 catcctgatg gggacaagtt ccaatttcgg gaacatgttc agcgtggccg gggcatccct
    43201 gtttctcacc ttccttccca tgctcccgat ccagatcctc ctcaacaacc tcctgtatga
    43261 cctctcggaa tcgacgatac ccaccgataa cgtcgatgaa gaccaggtaa ggtcaccgaa
    43321 gaggtgggac atggagttca tcaagaggtt catcctcgtc ttcggcccga tcagttctct
    43381 cttcgacttc ctcacgtttt tcatcctgct gtcctatttt gccgcggatg cacccttttt
    43441 ccagactgcg tggttcatcg aatcgatctg cacccagaca ctcgtcatct tcctcatacg
    43501 cacgagaatg gtccccttct tccggagcag gccaagcaga ctcctccttg cgagtactct
    43561 ctccatcgtg gccgctgcct gtctcctccc cttctcggtc cttggggaag tattcgggtt
    43621 cgtgcacctc ccccccgcgt tctaccttgt ccttgccggg ctcatctctg cgtatttctt
    43681 cctcgtggag gttgcaaaga agtggttctt tgggaagtac tcgttcctca tcgaacaggg
    43741 aaagggaaat gcactggttg catgacccgg catcactgcc cgggcctctc tttcattctc
    43801 cttcatcacg atgaagaccc ccgacgtgta acatagagga agaaagaggg aggcaatacc
    43861 ctgccatgag agtcccgtct ccgaggccct tcctgaagtg ggccggaggg aagacacagc
    43921 tgctccctgc cctggtcagg atggtcccgc ggaaggtacg cgagggagaa gttcccgtgt
    43981 acgtggaacc ctttgtcgga ggcggggcag tctatttcca tttcaacagc cgtttccgtt
    44041 tcagggagtg ccatatcttc gacgtcaacg aagagatatt ccttgcctac acggtcgtca
    44101 gggatcgcgt ggacgagctg atcgaggtcc tgcaggaact cgccggggag tatctctccc
    44161 gggacggcgc gggccggcgg gagtattacc gggaggtgcg ggatgcattc aacaaccgga
    44221 ggataacaat tgcccgcggg cagtttcatc cgtcatgggt cgagagggca gcccagctca
    44281 tctttctgaa caggacgtgc tataacgggt tgttccgggt caattcgcgg ggggagttca
    44341 acgtcccgta cgggaggtac aggaaccccc tgatcgtgaa cgaacctctc ctccgtcagg
    44401 attcgctcct cctccggaac acgtcggtgc acctcggtga cttttcccgg tctttcccat
    44461 tcatgtcgga ggaaacgttc gcctattttg atccccccta ccgcccgatc agcaggacag
    44521 cgcgattcac ggcatactcg caggatgggt tctctgacgc ggagcaggag agactcgccc
    44581 ggttttttgc agcctgcgat gcgaaaggcg cactgctgat gctctccaat tccgatcccc
    44641 ggaataccga tccctgtgac gatttttttg accggctgta cggcgatttc tctatcaccc
    44701 gcgtgcccgc ccggcgggcg atcaactcgg atggtgcagg gagaggcagc atatcggagg
    44761 ttgtggtgac caactaccca atcggtcgtt cagggaccct ttccctggag tgacaattga
    44821 aaacacgtcg tctcgtgaac cccaggaaaa ggagggacct ggatctcacc ctttttctcc
    44881 ggttcgttcc cgggtaagtc gtcggaactt cccttccggg acgaatatct cgaagcgggc
    44941 accctttccg ggaacaccgg tctcccggat ggaaagcccc gtgatggcga ggatctcccg
    45001 ggacaggaaa aggccaagac cggtatgttt tccaaaaccc ttcctgaaga gatatttttt
    45061 gtcctcctcc ggaattccca cgccgttgtc ttcgacggcg ataacaagac ccccctgttc
    45121 ttctcctgca gagaccctga tccgggagag ggaaggaccg ccgtaacgga aagaattttc
    45181 gaacaggttg aaaatgacct tctcaaagag gggatccgca tagacctcga tatcatccac
    45241 ctcaaggagg atatcgacac ccgatggcgg aaacccttcc cggattctcg cggcaatgtc
    45301 tgccacgttc tgccatgatg gttccctgac gccgatctcc tggtaatccc gggtgaaggt
    45361 gatctgttcc tctgcggtgt caaggacctt tttcatcttg tcgaggaatt ccctgattgt
    45421 tgttagttct ttttcgtccc tggcgagttc tatgtaccat ttcagggccg agacctggtt
    45481 gaggagatcg tggcgggtga tgctggagag gaggtggagt ttccggtttg caagggcgag
    45541 ggcatcctct gccatcttcc tttccgtgat gtcgttgaca aagaggagga tgccggagac
    45601 atttccctcg aggtcaagga gcggcacctt gtgtgtctcg acccaccgga ttcccccgtt
    45661 ccgtgtctgc atctgctcga taatgccaag cttgggtttt ttggtcgaga tgacttccaa
    45721 atcatccctg taatactttt cggccagctc cgggaagagg tcgtacgcac tttttccctc
    45781 gatctcttcc cggggaagac ctattgaagc cgccgctgcg gggttgacgc ggatgaaccg
    45841 gttctccgtg tccttgtacc agatcatggc cggggcgttg tcaaagatgg tttgcagttc
    45901 tgtcgtcaat gcgagcagtg cagcctggtt gcgcctgcgc tccgtgatat cacgcacgac
    45961 cgagaggaca acctccctgt tccggattat cacgcggtgg gcatggatct cgaccgggac
    46021 ggtgcccccg tcttttctcc ggtgttccgt ctcgaaaatc gcgtaccctt tttcgaggat
    46081 ctccctgccg atcacgtcga ggggcctgct gtggcctccc cgaacgaggt caagcggtgt
    46141 catcgcaagg aactcttccc tgctgtaccc gagcattttg caggccactg cgtttacctc
    46201 gataaaacgg cccgggagac cgtcttcgcg gagttcgtgg atatggatgg catcgtttgc
    46261 cgactcgaaa atttcccgga actttgcctc gctctcttcc agtgccgcct ctttctccag
    46321 cctctccctg acctcgcgga gtgcccggtc cctcatctcg cggtacgcac ggacctgctg
    46381 gacgagttcg gtcacgtcgt cgatgaatac cagtgcatag gtcttattcc cctccggaac
    46441 ggaatggact gtcgtcctct ggaaacggag cccccctccc ggaaggggtg cagggatgaa
    46501 atgggggtgg aactgtgtcg agaagaaagc agcagcaccg ccctcgaaga cctggccaat
    46561 gcggagagcg tacttcctgt ccgaaaggtg ggggtagagg tcgcggagat cgcggccgag
    46621 tactttctcc cggggaattc ctgtccattc ctccatcgtc ctgttccagc agatgaccgt
    46681 gtaatcggat tccagaatga tgatgccggc gggcaggatg tcaaggttct cgcaccggga
    46741 gaggaaggag ctcatcgtca tgaatggctg cccattaccg cggttatctt ttcaagcagg
    46801 gtatcaaggg cacctatttc gaatatcatc aggatgttgc cgacaacccg gaggtcttcg
    46861 attatgaact gcgacacggc gaggatgacc cagtcgtagt caggagaccc ctctctcccg
    46921 agaatatccc cgattccgcc ctccctgtat tccggtatcg agtagatcag gcgctccccg
    46981 aggacgtttg taatggagcc cattacggca ttgttcacga tattgccaac ctcgttcaaa
    47041 gtctcgatcc ggagcgcgtc gaggtcgggt tcctcgatct tctcccccgt gagggccatg
    47101 atcaggattg cggcactctt ttcgggaaag acaagcatgc tcatgcccga aaaagacccc
    47161 gagaacctga gtgtgacggc agagaggtgg gcgctgtcca ggagccgctg ctcacgtgtc
    47221 agatcggaat accgcaacac ccggacttcc ggaacctgga gccgtatgtg cgtcccggtc
    47281 atgtcgttga ggagcccggc ggcacgcccg acaccgatgt tgatcaactc gcggatcgcg
    47341 tcaatggact cttctccggc attcatgact tttttgcgct cccgatcgct ctcccgacgg
    47401 cagggatgag aacacccttg tctaccggct tgttgaggac atcgaaagcc ccgagctcga
    47461 ggcagatgtc ccgggtggtc ttctggatat cggaggtgaa gacaaggacg ggggtgccaa
    47521 gaccttcttc ccggaccatc cttaaaaaag tgtacccgtc gatcccgggc atcaggaggt
    47581 cgcagatgac gaggtcgggg gactccccga gggccaccgt gaaaccctcg cgtccgtctc
    47641 ccgcagtcag gacctggtac cccgcttcct cgaggacaga agaaatgagt ttcctctgga
    47701 accgcgagtc gtcgatgacg agaatttttg ccattccggc tctccatcct gaaaatgagt
    47761 tttcccattc cccgttcgac ctctttcctg ataaatttcg cccttcctct cccgctcccc
    47821 gcccctcatt cattgaacgt gcgatagagc ctgtttgcca gggactggaa gatcccgatg
    47881 gcaatgcaga gggcggcgat gtcaattgcg ggatggaaaa gagtggcctt tccaaacccc
    47941 gcctggacga ggtcgtttcc gtacgtcagg ggagagaggt atgcgatgat ctggccgggg
    48001 aaagggacct gccctatggg gacaaagacc cccgagacga agatgagcgg gaggcgcacg
    48061 aggttgagca tggacatgat gtcgcccggg ctctcggtcg ggtaggctgc aaagagggtg
    48121 cccatcgttg caaagcaaaa agagaggagg aggatcccgg ctgcgagggc cgggaggtct
    48181 ggcagcgatg tctggaagag gaccatgcct gcggcgaggg gaacgagcgc gatgcagcag
    48241 gcgtacagga aaccgctcat gctctcgccg agcacgacca tgtgcagcga gatgggggca
    48301 gagaggaggc gttcgaatgt ctttgtcctc ctctcgaggg ggatggaaac gggttcgatg
    48361 gaggacgagg agaagaggat cgtgatcgcg atcagccccg ggaccatggt cgccgggtct
    48421 gccggccggc cgaccgcgaa ggcaaggaac atgaagaggg gaaagagcat ccctgaaacg
    48481 atgatgttgg gcttcgcgta gtagatgagg atatccttgc gtgcaatcgc ccatgcagcg
    48541 gaaaaccccg tgcagacccc ggtgcagtac tctgacacgc tcctcaaggc ccaccgcccc
    48601 ctccctctcc gtccaggccc gtcagccgga tgaacacgtc ttcgaggctg gggcccagag
    48661 tgttgatgct gatgatgcgg agccccgacc tcctggcgta gtccgtgaca cccacgatga
    48721 ccgccggcgg gtcaccggtg atcagccgga tcttgtcgcc catcttccgg acaccggtga
    48781 cctgatcgat cccggcaaga tcctcagccc tgactgcgcc cggggggtcg aaggcaacct
    48841 cgatcgactg gacgctctgg atcgtcttct tgagccgttc cggcgtgtcg atggctgcaa
    48901 tccggcccct gttgatgatt gccaccctgt cgcagaggat gtttgcctcc tcgatgttgt
    48961 gtgtcgtgag aaatatggtc accccttccc ctgcaagacg cctgatgacg tcccggatga
    49021 tcaggttgct ctgtacatcc agcccggagg ttggctcgtc gaggaagagg aggcgcgggt
    49081 tgttgatgag gcccatggcg atcgtgagcc gccgtttcat acccttggaa aacccctttg
    49141 ttttgtcgtc cttccgcccg gaaagaccga agaccgaaag gaggtccagc gcccggctct
    49201 cgcgttccct tttccccacg ttgtagagcc tcgcggtgaa catgaggttt tcccaggcag
    49261 agaggtcggt gtagatgttg gaggtctcgt gcacgatgcc aatctccctg cgtgcaggga
    49321 tcttttcctg cacgacgtcc cggccaaaga tgcgcccgga accccccgtt ggctcggtca
    49381 tgccggtcag gatgcggatc gtcgtcgttt ttcccgcccc gttcggcccg aggaacccaa
    49441 acgtctcgcc ctcctcgacg gaaaaactga tgcctgcaag tgcctggatg gtgccaaacc
    49501 tcttttcgag ggagattgct tctattgcat gcatgggacg tcacaggagg gaaggtcagc
    49561 ctggaaagct ccccggagga tagtggggga tatggaaccc ttccgacgtg aaggtttctc
    49621 tccttgtgga acggcaggag gatcaaaatc caatcagcct tctccctgcc cggcagaaac
    49681 ggggattttt cctgtgcccg cccggaccgt cccgttctca atcccggcgt ttccggaatg
    49741 tgaggatgtt ttccccgtcc cggaactcgt aggagacctc gtccatcagc gtccggatga
    49801 ggtgtatgcc gaggcccccg acctctctct ccccgagggg cgcagagata tcgggctccg
    49861 gcacgaggag ggggttgaac gggacccccc tgtcccggag ctcgatggtg acgtggtcgg
    49921 gcccgggcat gacgccgagg acgagatctc cttctccgcc ggggtaggca tgggtcatga
    49981 cgttgacaac cgcttcctca acggcaagtt ccagatcgag gaggagccgt tcccggattc
    50041 cggcctctcc gaggacctgc cggaggaaac caaaaacctc cccgaggttc cggcggtccg
    50101 cccggagtgt gaggtgggac cagccggtca tggcaatccg accttcagga cgaggagtgt
    50161 gatatcatcg aactggggca tgccgcgggc gtgccgggcg acactttcca tgacagcgtc
    50221 gaggatatcc cgggccgtcc gttcccgcga agccacgacc gcgtctgcaa gccgcccggc
    50281 tccgaactcc tcgtcctgcg cattgacggc ctcggtgacc ccgtcggtat agaagacgag
    50341 aatatcgccc ggggagaggg ttacgtgcgc gtccgtgtat tcggcatccc cgatggcgcc
    50401 gagtgccggc cccgtgatgc cgagatccgc ccgcgtcccg tccgccctga cgaggagggg
    50461 agggttgtgg cctgcattga catacctgac ggttcgcgat gcagggtcga ccacaccata
    50521 gcagagggta acaaacatcc cgtaacgggc gtcggcagag atcatcctgt tcgcatcgct
    50581 gatgcactgc aggggggatc tgtgccacat cgcgttcgcc cgcgtcaccg tccgggaaag
    50641 cgccatgaag agggcggcag ggactccctt gcccgatacg tcagcgatga tgagaccgaa
    50701 aggttctccg gggccccgga cgatgacgtc atagaagtca cccccgacct cctttgcggg
    50761 aatgctccgg gcagcaaggt caaacccctc tatcgggggg atcgattcgg gaagaaaact
    50821 ctcctggatc tggcgtgcga ctgccagttc cgcgttcttt ctctcgagtt cggcgtggta
    50881 cgtgtccctt tcacccttcg ttttctgctc ggctgcaagg ttggaaatga taaacgcgaa
    50941 gatgaacatg ccgccggcgt tggcaagaac catggggatg ccgatctggg cgacgaggct
    51001 ctctgccatg gaacggggtt ctgccatgga gagcacgagg ccattgtgga ggacttccat
    51061 tccccctgca aagaggactg ccattcccac gccaataaat ttcctgccag aggagagcca
    51121 gaggagaccg ccaaggaggc ctgcaatcac cgtcgcgagg cagcagggga caacagtgaa
    51181 tcctcccatg ccggacctgt agagggctcc cacgaggccc gcacccagcc cggcgacggg
    51241 cccgccgagg agacccgcga ccatgggtcc gaggtcccgc acgttgacgg gggcgcccat
    51301 gatctcgatg gtcccccatg ttccgtaaat cgagagggcc ccgaacacga ggacgaggaa
    51361 cgcctggtgc ttccacgtca gtttccctgc caccacgtcc cggaatgtgg gtgtccgcga
    51421 gaggaggtac gcgatgacgg aaaggacgca gacgagctgg aagaggacgt ggattatttc
    51481 tgcatattca gtgagcaacc cggtagggac atccattcct gtgtacctgc acgcttccgt
    51541 tcaggagaag aagctcccga cggcctgctc ctcctgctcg aatatggtaa agatacggtt
    51601 gaacccggtc atcgcgatca cgtcacggac ctgcggctgg aggcaggcga gccggagatc
    51661 gccccccgcc tgccgtgcct gtttcagccc ggcgaggagg acgcggaggc ccgagctgct
    51721 gatgtacgag aggccagatg cgttgacgac gattttcgtc cggccagacc ggaccagtga
    51781 ctggattgcg ttctctccct ccggacttga gttggcatcc atccgcccgg aaaaaaggat
    51841 gatatcgaca tcacggtcct gtttcgtcga gacctggaag ggagcactta ccataggagt
    51901 attggtactc gcagtgtgac attattcttc ccctcattat ccaggccttg gagactttcc
    51961 cctcgtgaat cgcagcctgc tctctcccat tttcagccgg gcatcccacc cttggtttga
    52021 gtcccggccg gacttctgca tgtccggtga tttgacgcag gggatggaac gatgtcatcc
    52081 atcaccccta aaagaagtca tggtgcctga ctttttccgg cgttattgta tttataaagc
    52141 cgtccgggaa tctatccctg tgccggaatc cgataaataa accgtgttgt tattactccg
    52201 gaacgcagta ctatccctgg tagttcccga tgcgacctgc accacccctg cgtcctgccc
    52261 ggtggcagcc cctgcccggg gcagagggaa tgcgtatttt cccttttttt ggaaagccgg
    52321 actgcaccag ttcaaacctg tgcctcatcg ataccggtag cgagtttatc gtgatcgata
    52381 cagggacaaa cgagcggcaa ctcgaagatg tcgtccgact cgtcagggaa gtgccgggcg
    52441 gatctcttcg ccccgtcatc ctctttatca cgcactgcca catcgatcac tgctacccgc
    52501 tcctcgccgg gtcactgctc gaccgtctcc ccctcttcgt tgctgcccag gaagtggggg
    52561 cagcagcaat cgcaaccgga gacgtgcagt tgaccctcgg ggagatgttc aggaagcaat
    52621 tgaagcctca cgccgtccag attcccctcc tgtgcacggc tgaccgggag cggggaggag
    52681 agaagatcct ttccgtcccc ggccttggct ccgtacgcct tctgacagac gtgcccgccg
    52741 ccacggggcc tctccacacc gtatcccagc aggtcattct tcccccgggg acgtgccttt
    52801 cggtttattc aaccccggga cacacgccgg acagcatctg cgtacgcatc ggcagtgtcc
    52861 tcttctgcgg agatatcctc tttgcaacga cacccggcgt tgcgggtatc aggggttttt
    52921 cccgcgacga ccttctctcg acgatccgga cactccaggc aatcgttgac gcgggagaaa
    52981 tcaccgtctg gatccccggc cacggcgatc cgctcgggaa ccctgccatg gcaagggccc
    53041 tgcacaatct cgaaagggag gtcctctccc tgcgggaaat ccacacgttt gacctttccc
    53101 gtctcgagga gtcccgggac catgccctcg atatcctcga cgaggcagag aggctctttg
    53161 ccatcatcgg ggggcggctc ctcgcactct ctttcatcct cgagtccctc ggcgaggaag
    53221 cagaggcaga aaagttccgg gaagtcatgg acattaccgc gaccgacacg gtgctctgcg
    53281 atttccagca gttctgtgcc gatgtccgtg cagggaagag ggtcgaagtc cagctcatcc
    53341 ccaaggccgt ccaggtgctg cagaaactcc gaagatccct ctcctgcgag gaagtctccg
    53401 gtgtcgttga ccactccatc atctggaggg ccgagaggct ccttgatgaa tttctcgcaa
    53461 cggcccgcga cattccccgc gatccgacac ctgaccaggt ggatcttgtg tccctccttg
    53521 aatctctcgt tactaccgcg cactgccccc ccgtcccgga cgaggaattc atcgctgccg
    53581 cggaggacgc ggaagcgttc cggaaagccc tcgttgcccg gcttgccttc ctccctccgg
    53641 ttcctgctct ctcccttgcc ctcgaccgga aaaaaaccga cattcccccg gttgccagcg
    53701 acaggttccg gctctccgac agcctgatgg cccttctcga ggacctcgag gcagcagggt
    53761 gccgggatgc acgcctcggc gcccgccaga gagggtccgc ggtagaactt gtcatcgagg
    53821 caggttgccc gggtaaaaaa gagatattgt ccccccgcct tacccggaga cacgaacgga
    53881 gatttcacct ctgcggcgga gagttctcgg cagcccgtga gggggatcgg atcacctgca
    53941 cggtctcgtt tgtcgcagcg cggtaaggcg gcgaatacca aacttttatt gcctgatata
    54001 tgccagactc gtccatggca gaaagaccac tcggtgtcac tatcatcggt atcctctgga
    54061 tcatcggggg aattcttgca ctcctcggcg gattaggaat cgccgttctg ggtggcgcta
    54121 tcgcgggccc cctcggagct gctttcggac tggttattgg ttttgtactc gtgattatcg
    54181 ggctcatcga tatcatcctt ggcatcggct gcttcaaggc atggggatgg gtctggacga
    54241 ttggtgtcat catcacgatc atcggcctta tcctcggaat cattgacctt gtccagtcag
    54301 gagccagcgc tctgatcggg atcatcatct ccataatcat cctgtggtac ctctttaagg
    54361 acaacgtcaa gaagtacttt ggcaaggcct gaactgcgac ggagagcagg gaaaagtccc
    54421 aatttttccc gcatcgcacc catgacagga gtaacggggt gcgtcacgca gtggaaccgt
    54481 cagtaaaggg gactattgcc tttttccctc taaaatccct tttcccgata cagtaatccc
    54541 cccatgactc ccggcacagc ggcaggtatt aatagcggga acgggcactc tctcttcatc
    54601 caacgcctcc tccccttccc cggagttctc cgtgatcgac attctctgtg tggatgatga
    54661 ccccgatttc ctcgaaataa cgaagcgcat ggtggaaaga tccggcgcga tctcgataga
    54721 tactgcaagt tctgcagaaa atgccctcgc aatgatggag caccgtgcgt acgatgtcat
    54781 cgtctcggac taccagatgc cccgtactga cggtatcgag ttcctgaaaa cgctccgaaa
    54841 atcagggaat acaacgccat tcatcatttt taccggcagg ggtcgcgagg agatcgtcat
    54901 ccgggcctac gacagcgggg cggactttta cgtccagaaa gggggagacc tgaaggcaca
    54961 gttccgcgag ctggagcaca agatcgtgca ggcggtacgg atccacgagg cagagtctgc
    55021 attccgggag agcgaggaga gataccgttc cgtcgtcgag aacgcgaccg aggggatcgt
    55081 ggtcgtgcag gacgaacgta tcctgtatgc caacccgcgg gccctggaaa tggtagaggc
    55141 cactcccgac gaggtgacag gaaagaactt cgccctcttc gttcaccccg atgacatccc
    55201 gctcgtgacc gggaggtact acaagcgcca ggaaggagta ccgattccca agacctatga
    55261 cttcaggata gtcgggaaag ggggacatgt cacgtgggtc caggcatcgg cagtcctgat
    55321 accatggaac cgccggcccg caaccctcgc tctcctggca gacatcacgg agaggaggga
    55381 gcgcgagaat ggtgtccgtc agcgaaacgt cgacctcgaa aagactgtgg aagaccaggc
    55441 tgcccggctg gaaaagtcag aaaacgagaa gaaagacctc ctcaggagac ttgccgggga
    55501 tgatgccggc tgacaggaac gatcaattcc tccaccatta cgggtgacct ttattcctgc
    55561 cagttcatcc ctccgttcca ggcattgcac ccgccggtgt ttcacgagag atgagttttt
    55621 ctcctgtaga ttccatcctt cttcatccat ttcccttcgt gaatgaaaac cgggatcagg
    55681 agcaatgaca aacccgtacc gcatcctgta cgtcgacgat gaaccggcac tgctcgatat
    55741 tgtccggctc tacctcgaga ggaagaagag gttcatcgtg gacacggcaa cgtctgcagg
    55801 cgaggcgctg aaaatgatgc aggggaaccc gccctacgat gccatcgtct gcgattacca
    55861 gatgcccgtc atggatgggg tcgggttcct cagggttctc cgcaagcacg gggatgatac
    55921 gccctttatc atattcaccg ggaagggcag ggaggacatt gtcatccagg ccctgaacga
    55981 gggtgccgac ttttacctcc agaaaggagg tgaccccgca tcccagttcg ccgagcttgc
    56041 ccacgtcatc cagaaggttg tccgccagaa gagaatcgag tcaagcatcc gcgacatgga
    56101 acgccgcgag gcagacatcc tcaacttttt accggatgct acctttgcca ttgaccttca
    56161 tggtacggtg atcgcatgga accgtgcaat ggagaagatg acagggattc ctgctgacca
    56221 gatgctcggc aaaggggacc acgagtatgc cctcccgttt taccgtgaac ggcgcccgat
    56281 cctcgtcgac ctcatccttc aatccgatcc cggaaccgag gccaggtacc cgtacatcag
    56341 gaaggaggga gagaccctca tctcggagat tttcataccc tctttcaatg acggaaaggg
    56401 tgcccacctc tggttcctcg cgtcgcctct ttacaattcg cggggagagg ttgtcggtgc
    56461 gatcgagtcc atccgggacg tgagcgaatg gaaggacatg gaaaaggaga tggaggagag
    56521 ggggaggttc ctctccacgc tggtcgcaaa cctcccgggc tttgtttacc ggtgcaggaa
    56581 tgaccggaac tggacgatgg aatacataag cgacgggtgc cgggacgtga cagggtacga
    56641 accgtccgat ttcatcggga atgcgacact tgccttcaat gatatcatcc accccgacta
    56701 ccggaacgtc ctgtggaacc tctggcagga aatcctcgca gatcggcggg tattcgaata
    56761 cgagtacccc attaccaccc gccatggaga gacccgctgg gtgtgggaac gggggagggg
    56821 tatctactcg gaggatggca ctcttcttta ccttgaaggg ttcatcacgg acatcacggc
    56881 ccggaagaac gtcgaagacg aactccggaa gagccgggag cagctcgccc ttgccatcga
    56941 ggggtccggg gccggtctct gggactggaa ggtccagaca ggggaactct catgtaacga
    57001 gaggtgggct gaaattgtgg ggtatacacg ggatgaactc gaacccctca gcatcgagac
    57061 ctggacccgc cttgtgcatc ccgatgacct ggaggtttcc aattccctgc tccagaagca
    57121 ttttgcccac gagaccacct cctacgagtg cgaagtgcgg atgcggcaca aggatgggca
    57181 ctgggtctgg atcctcgatc ggggaaaggt gacggagtgg gacggggagg gaagaccggt
    57241 gcgcatgacg ggaacccacc tcgatatcac ggagcggaaa cgtatcgagg aggagctccg
    57301 ggagagcagg gaaattctcc acaatttcat cgggaacctc ccggttggcc tgtaccggaa
    57361 cactcccggt gcccggggcg agtacatcat ggcaaacccc tatattgccc ggctgcacgg
    57421 gttcgagacc ctcgatgaat tattcacgca tcctgcagca gacctgtacg aagatccctc
    57481 cgaacgcctt gcgttctccg acgaactggt gcgggccggt tccgtgttcg gcagggagct
    57541 ccagttaagg agaaagaacg gggagcggtt ctgggggcgt gtctcggcag tcgcggtacg
    57601 cgatgaaaag ggcaatgtca agtactttga tggagttatc gaggacatca cggagcaaaa
    57661 aaaggccgag aaagcgttcc gggagagcga aaagaaatac cgggatctcc tcgaaaaact
    57721 ccccgaacag gtcatcgtgc accggggagg cctcatcctg tacgcaaacc ccgcaacctt
    57781 caggacactg ggatacaagc ccgaagaggt tatcaaccgc catgtcctcg agttcatccc
    57841 cccggaatac cacccccggg tcgttgagac ccttcgaaag agggatgccg ggcaggaaac
    57901 ggagtattac gagatcgaga tccttggaaa agatggaacc cggaggacca tgagagtcag
    57961 cgggaatcct atcactttcg atggcgagcc ggcaaccctc attgtcctct ttgacatcac
    58021 cgaaaggaaa cgtgcagaac aggcgctcca gcaggcaaac aggaagatag ccctattaaa
    58081 cagcgtcaca aggcacgata tcagtaacca tctccttgtg ctcaccggtc ttcttgaact
    58141 cctgcaggac accatggagc catcggaaag ggcggacctc ctcgataaag tacgcagggc
    58201 ggctgccagg atatctgcag cgatccagtt cacgaaagat tatgaaaaga tcgggggcag
    58261 cgatccccag tggcaggata tccacgatct cgtcgagact gcgaaggcag attttgtctc
    58321 tccggagctc gtgattgaaa accagatacc ccgcggcctt ctcgtatttt ccgattccat
    58381 gttggcaaaa gtcataacga acctcattga caattcagtc cgacacgggg ggaatgtaac
    58441 atctatccgg ttctcgaccg ctggggaggg gaaaaacctc ctcattgcct acgaggatga
    58501 tggcgccggc atcccggatg gagagaaaga aatgattttt gagaggggat acgggaagaa
    58561 cacgggatgg ggacttttcc tgtcacgcga gatccttgcc atcaccggga tgagcatcag
    58621 ggagaacggc gtgccggggg agggggcgcg gtttctcctc accgtgcccg gtggctcgtg
    58681 gaagtatgtc accctgcccg ccgcagggaa ggaaacctga atttttaacg agaatcgtat
    58741 ccatggtttt cattttgtat ccctgtgtcc gttaaaaacc tgtaattcta ttgaatatgc
    58801 aaccaggaat gcaggattga aaaacgaacc tgcctgaatg aactcctttc attcccctat
    58861 ccagcctgtg atacccatta ccagctgtgg aggttcacca gagacgtttg catgatacat
    58921 cagatatgcg ggaaatggat tcacccgggg aaagaatctg agaaggagag cgatgatact
    58981 ggaatcaacc ggaagaaaac ccccggacat gttccccggg actttatttc ctcccccctc
    59041 agatcttcag gatcggtccg agtgccaggg agaggtagga tatcccgaac aggacgagaa
    59101 atgccccgca cccccggagg acccatgcat
//
LOCUS       DAOOJU010000009        57993 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_631_length_57993_cov_17.043512, whole genome shotgun sequence.
ACCESSION   DAOOJU010000009 DAOOJU010000000
VERSION     DAOOJU010000009.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 57993)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 57993)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57993
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_631_length_57993_cov_17.043512"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            78..935
                     /locus_tag="PK679_03700"
     CDS             78..935
                     /locus_tag="PK679_03700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ARMT1-like domain-containing protein"
                     /protein_id="HPC55094.1"
                     /translation="MRWDPRCFPCLLSRVSLECTLCNADPALSRRVRDECERMLNDLK
                     ERPLLHPEVASALHRHAYGMLGTRDPFSALKEESTKKALEVCRTVRPRLKSFRDFVTA
                     AVIGNTFDFGVLSHSVEPDFARYFEHEFAEGLFIDDTDRILPLTDRVVYFTDNCGEIV
                     FDRLLVEYLSRRGSEITVAVRDEPILNDATRADANDVHMEKFASLVTTTGCGCELGVR
                     LDCMPDDLARAMDTCTIVISKGMANYESLSEYSRLPPVAYLMAVKCDPIADEVGVPRG
                     KKVAMLRVN"
     gene            complement(983..1570)
                     /locus_tag="PK679_03705"
     CDS             complement(983..1570)
                     /locus_tag="PK679_03705"
                     /inference="COORDINATES: protein motif:HMM:NF016764.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HPC55095.1"
                     /translation="MSESVLNKIRGFLFSPSLSFRRAKDEEAGDTITYLIILAVFYSL
                     MGTLLTVLEISIHPFAVLSSFHPGPAEALLIVSLIVVILVFTLIMAVVFGLFLHIFVY
                     LVGGRKGVWQTEKAVFYSLTPVFVLGWIPLIGIIVGGIWSIVLGVIGIRELQGVSDTK
                     AAIAMIVAIVIAAVIAVVILGAMLFAVVSSIRMTA"
     gene            1735..2193
                     /locus_tag="PK679_03710"
     CDS             1735..2193
                     /locus_tag="PK679_03710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HPC55096.1"
                     /translation="MVELVGLSFGWILIILGTIFLVIEASNPGFFIAVPGTVMIILGA
                     MILLGVDIFSGPLGLVAGVISAVIVSLVTIWLYRRINPGDAAPVTISRDSLVGREGRV
                     IRRVTPADLSGKVVVSGQEWSARSRDGEIPAGATVRIIASEGVHVVVEKV"
     gene            2199..3320
                     /locus_tag="PK679_03715"
     CDS             2199..3320
                     /locus_tag="PK679_03715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HPC55097.1"
                     /translation="MAVIETLVTFFLIIAIVIIFARGVVIIQPYEQGLAIRLGRYTGR
                     MNPGFRWVFPLITNVVKMDLRTQVMDVPSQEVITKDNSPTNVDAIVYIRVIDPEKAFF
                     EVANYRMATVALAQTSLRGIIGDMELDEILYNRDIINTKLRDILDRETDQWGVKVERV
                     EIKEVDPVGAVKQAMTEQTAAERARRAAILRADGEKRSAILKAEGTKRSMILEAEGDR
                     QSKVLRAEGERISRILQAQGEAQSLRILSVGARPLDRRAITVLSLDALKTMADGQATK
                     IIFPFEVSTLMKQAARFLGASEEGGGGEEGMAPAGVPEADILGTIPTADEVKEILREM
                     DTSVKTEISVEDLKDISRTRKKTGSELVDEIEKDASTMD"
     gene            complement(3678..3866)
                     /locus_tag="PK679_03720"
     CDS             complement(3678..3866)
                     /locus_tag="PK679_03720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55098.1"
                     /translation="MSTVIQFESVIEFVADINGEKDCLMSQDKTQDEPGTLWFNIDVP
                     KGHGVRAGDRVRITVEKI"
     gene            complement(3900..4151)
                     /locus_tag="PK679_03725"
     CDS             complement(3900..4151)
                     /locus_tag="PK679_03725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55099.1"
                     /translation="MNTSRNIRQCYNETQARIVQYLKGGLEKGKIYFKSKYIARELGL
                     SPKEVGTNMAILSEICQELAIIKWSYSNSTTWMVTSRSV"
     gene            complement(4336..6150)
                     /locus_tag="PK679_03730"
     CDS             complement(4336..6150)
                     /locus_tag="PK679_03730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="HPC55100.1"
                     /translation="MSPGCDLGDVEVGKTYIGRVQGFANFGTFVQLNDRVKGLVHKSN
                     VRTQHKERDSILVRVLNIRTNGNIDLEEVTIPVYTVEMVEKKSTAVRLAELGGKVGKT
                     VRIEGEIAQIKQTSGPTIFTIVDESGTENAAAFVEAGVRAYPEAECGDMVRIVGEVMM
                     RQNQLQIEVESLTILAGKDAEAVRERIEKALDIRSEPPDIPLLIESPVLEKLKPEMRK
                     VAKIIRRAVFTSQPIVLRHHADADGICAGVAIEQAVIALMRESGADFDADYFLFKRAP
                     SKAPFYEIEDIIRDLDFATKDNVRYGQKMPLVILMDNGSTEEDLPSMKMAQVYDLSMV
                     VIDHHHPDAVVDQYLVGHVNPYHVGGDFGITAGMLGTEVARLVNPAVEPVIRHLPAVA
                     GVGDRSEAPERARYLALVQDTYTEENCRDIALALDYQQFWLRFNDGREIIKDVLNLAG
                     DTERHGKLVAHLVEGANLAIQDQMSACMPHVRHQTLQNGAELFLIDVEIHAHKFTFPP
                     PGKTSGEVHDRLCQQHAGSPVVTIGFGPDFAVLRSRGVMMNIPQMVRELREEIPGGGI
                     SGGGHLVVGSIKFVEGMREEVLNGLIAKISRVKTGMPA"
     gene            complement(6302..7249)
                     /locus_tag="PK679_03735"
     CDS             complement(6302..7249)
                     /locus_tag="PK679_03735"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - endoribonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042779 - tRNA 3'-trailer cleavage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HPC55101.1"
                     /translation="MSGETLHVYFLGTAAALPTPLRNPSCIMVRRGHDTLLFDCGEGT
                     QQQMMRARTGFLVDGIFITHWHADHFLGIFGLAQTLSFMGRTEPLTIYGPEWVTEVAA
                     AVKSLARYNIRFPVIPVELRPGSAVRFEGYTVRAFGTDHGMAGLGYVLCEDPRPGRFN
                     RQKAIDLGVPPGPLFGRLQRGETVRVVRNGDTVEVRPDEVMGPPRPGRKIVYTGDTRP
                     VHSRIADVAGGADLLIHDATYDDSARDRAEEVLHSTAGEAGEAAAFLGAGTLALVHIS
                     SRYTTVAGHMRDAQARFTGRVIIPSDLEMIEVPYKDSRE"
     gene            complement(7246..8019)
                     /locus_tag="PK679_03740"
     CDS             complement(7246..8019)
                     /locus_tag="PK679_03740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HPC55102.1"
                     /translation="MSFRIYFSSSSKVWDDISWIYGIEEAGFDGWEIVADGSYRLDNP
                     ENVRRIDEAIASTHLGITVHAPYADLNLATLNHPIWRESVRQVSCCIEQASEWTDRVT
                     VHPGYISPVGKIMPDRVWEFQKVALREIGKVASDHGVVACLENMIGAREFLCRDPGEL
                     LGMTEGIGGVGITIDIGHAHTMGLVRDFLPLVSRASHMHVHDNHGQSDEHLPIGDGSV
                     DWEAVGPVIGRNFAGVVVIEGRGVAEGKRSLAVVRGWQE"
     gene            complement(8016..8564)
                     /locus_tag="PK679_03745"
     CDS             complement(8016..8564)
                     /locus_tag="PK679_03745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HPC55103.1"
                     /translation="MKVIGVVGFPASGKGEFSRVAAEMGIPVVVMGDFIREETRKAGL
                     PPTDENLGAVAQQLRRNGGMDAIARRCIPRIRATGARLVLVDGIRGDAEVRLFREAFP
                     GFALVGIRAPFSERAVRLAKRGREDDQDTPRALEERDQRELAWGLDRALAGADHIIEN
                     EGTLEEFVRATRALLRKIAEDP"
     gene            complement(8524..9351)
                     /locus_tag="PK679_03750"
     CDS             complement(8524..9351)
                     /locus_tag="PK679_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0051353 - positive regulation of
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HPC55104.1"
                     /translation="MQVNFGGFVDLSTIDWPGRAVCTVFLRGCPLRCSYCHNAAIQTG
                     SDMREVGWLVEKIARVRPLVSGVVFSGGEPTMQREPLVALARAARGMGLLVGIQTNGY
                     FPETIRQLLSERLVDRVALDYKSRWEGFSKRWEGYGNVCREDYTRQVRESVALCQDAH
                     VAGILPSFEVVLTVFWGNEREILAIEKELPRGTIVLQQGVHKRFWKDWTLAREVKGKP
                     YLSAEEVNGPRPPLSLEELSALASKMVRVGRTIRIRTRETGEVMYEGDRGRWVPCKW"
     gene            9585..10859
                     /gene="thiC"
                     /locus_tag="PK679_03755"
     CDS             9585..10859
                     /gene="thiC"
                     /locus_tag="PK679_03755"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HPC55105.1"
                     /translation="MSLIDDARAGRITEEMRVVAKQEGVTEDFVRRGIAGGHIVIPVS
                     PYRKVRICGIGEGLRTKVNASIGTSTDIVDVDMEVEKARQAERAGADTLMELSTGGDF
                     VEIRKRVIAATTLSVGSVPLYQAFIEAARKDGAVVHMKEDDLFRITAEQAKLGTNFMA
                     IHTGINWETVKRLRNQGRHGGLVSRGGAFMTAWMLHNEKENPLYSEFDYLLEIMKEHE
                     VTLSMGNGMRAGAVHDATDRAQIQELLINSELADKAHAEGVQVIIEGPGHIPIDEIQA
                     NVVLQKRVSNRKPFYMLGPLVTDIAPGYDDRVAAIGASLSSAYGADFICYVTPSEHLA
                     LPTPEEVYEGVISSRIAAHVGDMIKLKKREADLEMGHARRDLDWERQFQIAMNPERAR
                     QIRSERMPADADACTMCGDYCALKIVNRHFSF"
     gene            complement(10976..11317)
                     /locus_tag="PK679_03760"
     CDS             complement(10976..11317)
                     /locus_tag="PK679_03760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HPC55106.1"
                     /translation="MTKTPEDALKVIQSHPEGVLQSDLWKILDVDSRKCSRLVKKLLD
                     DGLIERIEFRKEGIKTFVLKAVRCPVDPAHLLAGDELIPCIGCDLECRVEECPRLLDW
                     MYQLAISDAEK"
     gene            complement(11343..11579)
                     /locus_tag="PK679_03765"
     CDS             complement(11343..11579)
                     /locus_tag="PK679_03765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoprotein"
                     /protein_id="HPC55107.1"
                     /translation="MVNGIVLPIKKVFSLVDSRIIVEIKDDQRKLQGRLVAVDEYLNI
                     HMDDTTEYVNNVRGRTLGTVVIRGNNILSIQPQA"
     gene            complement(11666..12763)
                     /gene="fbp"
                     /locus_tag="PK679_03770"
     CDS             complement(11666..12763)
                     /gene="fbp"
                     /locus_tag="PK679_03770"
                     /EC_number="3.1.3.11"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphate aldolase/phosphatase"
                     /protein_id="HPC55108.1"
                     /translation="MPKTTISLIKADIGSFPGHSRTHPVILEKAARLLKEQEGKLLID
                     SFVTHCGDDLELIMTHTRGEDNKEIHALAWKVFQECAKMAREMKLYGAGQDILSDAFS
                     GNVKGMGPGVAEMEFEERGSDPVLLFMADKTEPGAWNFYLYKIFADPFNTAGLVIDPS
                     MHEGFIFEVHDVIEKRKIEFRTPEESYSLLAYIGAPSRYVIKSVRRKDGVIAASTSTQ
                     RLSLIAGKYVGKDDPVMIVRGQSGLPAVGEIIDPFATPIIVAGWMRGSHHGPFMPVGL
                     PDANCTRFDGPPRVICLGFQVCNGKLIGPADMFDDPAFDRVRARCNELADILRAHGPF
                     EPHRLSLSEMEYTTLPAVEKTLKNRWVPIGE"
     gene            complement(12851..13297)
                     /locus_tag="PK679_03775"
     CDS             complement(12851..13297)
                     /locus_tag="PK679_03775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55109.1"
                     /translation="MTERQEDPRKTLEEMVRHLIAAAHDGRLQPVFVGMNVIISPGGG
                     FPVPPQRARGDGKEPDIEIQRIGDRILLVTELPGLSPENVQVLFRGDRVFIWGKDGER
                     QYRTSAAVPPPRAGSEQVTYRHGVLEVSYVPMETSGTGNPPAPREE"
     gene            complement(13362..15743)
                     /locus_tag="PK679_03780"
     CDS             complement(13362..15743)
                     /locus_tag="PK679_03780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDC48 family AAA ATPase"
                     /protein_id="HPC55110.1"
                     /translation="MADSDTIEVIVKEAARDDAGRGIARLSIEAMRKLGLVSGDAIEI
                     QGKKKATAIVWPGFPQDTGQAIIRIDGTIRSNAGTGVDERVKIRKVEVGYAKKVVINP
                     TQPIRLVGGEQYLSRILRGRAVMEGQTVRVDVIGNPLTLVISKVSPKGIAIVTEDTQI
                     ELKETPYEPEERKKGEITDVHYEDIGGLTRELELVREMIELPLRHPELFERLGIDPPK
                     GVLLYGPPGTGKTLIAKAVANEVDAHFISISGPEIMSKYYGESEGRLREVFEEAQENA
                     PAIIFIDEIDSIAPRREETKGEVERRVVAQLLSLMDGLKARGQVIVIAATNIPDAIDP
                     ALRRGGRFDREIEIGIPDKKGRLEIFQVHTRGVPLADDVRLDDYAETTHGFVGADIAL
                     LVKEAAMHALRKVLPRLDLDKEIPADMLEQLKVTKEDFEEARKHVEPSAMREVLVEVP
                     DVTWEDIGGLDEVKQELREAVEWPLRYPQVFEKLQTRPPKGILLFGPPGTGKTLLAKA
                     VANESECNFISVKGPELLSKWVGESEKGVREVFRKARQASPAIIFFDEVDALVPKRGM
                     YMGSSHVTESVVSQILTELDGLEELKNVTVIGATNRPDMLDPALMRPGRMERHIYVPP
                     PDAESRKKIFEVYLGSGGQLVTGDVKIDDLVAVTEGYVGADIEALVREAKLCAMREFI
                     SVMGGKSEQEIADAVVNVRISRKHFDEALKKVKGSMDRESLEAAERMAWEILYNQEQR
                     TILENAVAALKQAEIRTGRTYDTEPLRKATFARKKDWNEIKRLTHLLEEELKA"
     gene            16022..17299
                     /gene="serS"
                     /locus_tag="PK679_03785"
     CDS             16022..17299
                     /gene="serS"
                     /locus_tag="PK679_03785"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HPC55111.1"
                     /translation="MLDIRFIRENPEVVRADLRRRGRDGDVRMVDDLLEKDRRSRTLK
                     VEIDKLRQRRNSIAREINEARKAGRDTSDLLQEASRLPEKIKELESVIESLSSEITGV
                     LMSLPNILHESVPIGRDDSENLELRRVGTPRTFDFPLRNHGELAAECGWADFERAARA
                     AGAGFYYLKGSLVLLDLALQRFAIDLLTKKGFIPVIPPYMMNRSSYEGVTDLADFENV
                     MYKIEDDDAYLIATSEHPLCAMYQDEIFEERDLPLRLCGVSPCFRREIGSHGLDTKGL
                     FRVHQFHKVEQFVFCRPEESWDIHEQLLAHAEEIYTLLGLPYRVVSICTGDIGTVAAK
                     KYDIEVWMPREEKYREVVSCSNCTSYQAVRLRIRVRDPRNFESKRYVHTLNSTAVATS
                     RTIRAILENYQEADGRVAVPRVLQPYMNGAEYL"
     gene            complement(17272..17874)
                     /locus_tag="PK679_03790"
     CDS             complement(17272..17874)
                     /locus_tag="PK679_03790"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HPC55112.1"
                     /translation="MCISKEVLRTRAREARAAIPEEKRKEYSCTICNRVVSLLDGQDP
                     VLVYVSKPPEVETIPLITTLFSRKTSVVVPIIEREERTLRLSFLRDPSHLSISTFSVP
                     EPIGHEFPADPGSIHVAIVPLIAYDRNGHRLGYGAGYYDRFLSRNPHMFKIGIGFSCQ
                     EVDQIPADSRDVSMDVIVTENEIIRTGEKRAVQRYSAPFM"
     gene            18312..19475
                     /locus_tag="PK679_03795"
     CDS             18312..19475
                     /locus_tag="PK679_03795"
                     /inference="COORDINATES: protein motif:HMM:NF024804.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HPC55113.1"
                     /translation="MRIAWYIPAIVVLLFICIIAYPACAAGGGGGHANPNQFGLGEGK
                     GIQHGNGAANTGNAMQGVPDPSISPPKNSQGKGPVLSGNSAGNPSGGPSPLVGRLTGT
                     AAPSSSPGNGAGPVRSPMPRNPHSPGPWHSVPVPVQDRYPCGPAETSGPLPAGGPAEP
                     SAHVSPGMPRVRREEGDAEDDGGSPPLPGYPVPAPFLPALGYRRITRKTVLASSVRNR
                     VYTAIAENPGLDAPALAALLGMNINTLRYHLFTLAREEKITYFSRPGTVRYFVNNGLF
                     PPRLQCLFHYLRGESTRKIILALAESPGMTREALATTLGIAGPSVTRHIQNLSHDGIV
                     EVRKQGRFSCHYLTPPILAHPAVIDGCSVHQYPSRESVLACNSHLPRGSPAET"
     gene            19581..19961
                     /locus_tag="PK679_03800"
     CDS             19581..19961
                     /locus_tag="PK679_03800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55114.1"
                     /translation="MKKILTLCILLLVLVPATVMAAGAHGQGKSGAGAPALGIGEQSL
                     ESAPACGQNRFCTMNGQENADQYRFAEMHRVSAGRGIGDQVRIMARNQTGLQDGIGDQ
                     VRIMARNQTRLRDGSCGNCRVQTG"
     gene            20260..20793
                     /locus_tag="PK679_03805"
     CDS             20260..20793
                     /locus_tag="PK679_03805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6125 family protein"
                     /protein_id="HPC55115.1"
                     /translation="MELDRIREMNRDGILSYIEFLLWHYRVVDAFWFIYVTERFGQPV
                     AEQINEQVWGRVAGMAARDLKERFSLKKKGLRGFSEALRLFPWALIVGYLIEEGEDEI
                     LIRVPHCPTQEARLRRGLDEYACREMHRAEFSSFAREIDPRIRVECLFAPPDPHPEDL
                     FCMWRFTVADENTPIQR"
     gene            20877..21821
                     /locus_tag="PK679_03810"
     CDS             20877..21821
                     /locus_tag="PK679_03810"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HPC55116.1"
                     /translation="MRFDPGYTIPSRVTWCMIWFPLALAGAMAQAMYSAGAKILLRQV
                     PAAQVAGGSFLVAAVSLAAISFSRGFPSIEPGFSEAVLVTVTINTVATVLFYRALSLS
                     DLSLCLPILSFTPVFLLLTSFFILGEIPSIAGLAGIFLVAAGSYLLAADGTSGKARGW
                     TGPFRFLLSDRGVRFMLVVAFLYSISVNYDKVVVERSDPVFASAVVLGLLACIFLLQA
                     SIPVLSGKSYPPLPREKSRGTSLLMIGLGLVLTMEAVTVNTAYTLSLVPYVIAIKRLS
                     VLFGVIIGGYLFREGSIRQRAFGTIVMVTGTVLIAVWG"
     gene            complement(22105..22177)
                     /locus_tag="PK679_03815"
     tRNA            complement(22105..22177)
                     /locus_tag="PK679_03815"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22141..22143),aa:Gln,seq:ttg)
     gene            complement(22340..23581)
                     /locus_tag="PK679_03820"
     CDS             complement(22340..23581)
                     /locus_tag="PK679_03820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55117.1"
                     /translation="MEDFHQKVPSKRQELDIALEAVILLVLSVFMLLFGVLLFFIHTG
                     DLPYAPDSTYGLFLVIVSLQVITMGRTPFGDVRRSWLVTIVGISASVIGMGACFIPES
                     LSALVRILVGVLLLSGGAVLLFQLASRRDRAPAWLKVPGILRHLTLACFLVYLMAFIL
                     GLVTILPALTTDWLTAVFLIVYGISLLYLAWCIQVVRKEYPESSLPPSTGPSEERHFF
                     LLREAPLTFTTALLVFLGVLLAFLAVLLVPITMGTLPFSPDGQFGLLLVIMAIQVLAV
                     GETPVGRFRRSWTLVTIGLAFVALGVFSCIVPGIMTDVLRIMLGILNIAGGIVPLAIR
                     IFPLLQQMGTPKAPPVPIPTPLRNLLLTQTVLNIVSILFGTSMLLPGLIPGMVTAAIL
                     FCNGILLFVLARILSTLPSAA"
     gene            23725..25059
                     /locus_tag="PK679_03825"
     CDS             23725..25059
                     /locus_tag="PK679_03825"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC55118.1"
                     /translation="MRNVSMVSFSLRSIPAVILLAIALVACTGQVSAMIGGGTGYFQI
                     SSSPSGATVYFDGTYRGETPVTIPVSTTGTPSHSIRITKTGYTEWTDTYEGNPFEGET
                     IHISATLQPLPGGGKGYYRISSSPSGASVYFDDSYKGTTPLTITVSTTGTPGHTIRLV
                     LSGYQEWSSYQPGNPGEDETVYVTATLQPVQTYGSITVTSSPSGATAVLDGAQSKVTP
                     CTFDNVLPGLHTVQVSKSGYQVWSTTTSVSSGLNTQVFASLSPITPATGSIYVTSVPS
                     GASVYVDGTYYGPSPQLASGLPPGYHQVRISLSGFQDWIGNVLVNSGETTRVSQTLSV
                     TPTPTQVSGTGSLSVQSNPAGASVYLDNEYMGITPLVIPSVPPGMHTVLLTHPGYTDW
                     RATIQVNRDTQTPVDATLSPSPTITPTKAPLPAVLALLGMGIPVLVVWGRRR"
     gene            complement(25277..26062)
                     /locus_tag="PK679_03830"
     CDS             complement(25277..26062)
                     /locus_tag="PK679_03830"
                     /inference="COORDINATES: protein motif:HMM:NF024816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55119.1"
                     /translation="MTATDQRMTFHFFILLILIPLISLPVAAGDSPGPDESIPVMTAS
                     LWNDRGNTYSSQLRWDLAIDAYSHAIELDPGFARAYFNRGKAYAELGRYDDAIADYEM
                     AIDRNPSLKGVIEHFLDTAVRNRYVTIPGEALLKGTLLPGGQFLAVDNTKGTSDVVVA
                     LTPRGQRGAILAVYVAKGHSHRFDQVVPPGIYDVYITTGERWNPKEKAFAVETGYLMW
                     KAPQVFAGSGNSGLTLTFIQWYPPSSWWDPALIPINPEQFPVV"
     gene            26189..26893
                     /locus_tag="PK679_03835"
     CDS             26189..26893
                     /locus_tag="PK679_03835"
                     /inference="COORDINATES: protein motif:HMM:NF016214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HPC55120.1"
                     /translation="MYVMCHLLSGIVPGTLLSYSAGDRRMAIACTVGAILPDLVDKPL
                     GLVISGTVGYGRIYSHTLVMGLLFFGLGIVSWAFLRKYAWNTGVLVALGMGFLLHQIL
                     DAMWQTPATWFWPFLGPFPPGERIAIIPYILADILQPAEWLAGIAFIFLFAWLIGAGR
                     ARAPYGAGLSLVLGFSALWLTICALGGSFCPLTGWDSRSDNLIVALVLLGGAICLAME
                     NAGFMQGEGKDSKRLQ"
     gene            27014..28090
                     /gene="wecB"
                     /locus_tag="PK679_03840"
     CDS             27014..28090
                     /gene="wecB"
                     /locus_tag="PK679_03840"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HPC55121.1"
                     /translation="MFTFVLGTRPEIIKCSPLIRLFEREHVPYSIIHTGQHYSYEMDR
                     IFFEDLQLPEPEYSLDAGSGSHGRQTGTILEGVERILIAHTPSAVLVQGDTNTVLAGA
                     LAAVKLHVPVAHIEAGLRSFDRRMPEEINRVVTDHISTYLFAPTTLAERNLLSEGIDP
                     GTIHVSGNTIVDAVFQNLDISRKKSGRVTGTGGLKEGQFILATAHRAENVDVKENLKG
                     ILEGLKSLGNETGMPVVFPVHPRTRKMMEMFALESDGLFTIPPVGYLEFLRLEASSCL
                     VLTDSGGVQEEACILKVPCVTLRENTERPETIDAGANVLAGTDPLRIVREGLAMIGKK
                     RDWKNPFGDGHAADRILEVLLERL"
     gene            28168..29325
                     /locus_tag="PK679_03845"
     CDS             28168..29325
                     /locus_tag="PK679_03845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55122.1"
                     /translation="MHGRRSLAVLLFLFLLIIPVAPVTITGRPETVSNGHPLFVTITS
                     LPDGAQFSLLVEATYDVSPNTDFQFQMSQFKMPFSLKKGSITATLEGTSQNRLEVKKE
                     DTIVSVSGKSTDGRFTTTKSYDITAGTYDYFRLSGTTLPSARSITTRFQVTGVKQGPV
                     DSEIGFVVDGLPSGTITLAALVDGTQVLYKTIPVGSGEPPRLISQPSTTTGPSVSQET
                     VSFTSIDETVKVRVPPGVQISVVGVPLPAAPEEMQVIAGPYAIVPYEAVFSPPGEILF
                     STGNTGAGNNTAVAFFSGDSWTLLPSMAAGNHVAAPLGKGGMYALVRPAGTVHTQTIT
                     TKTTMPATMTTVPATQMTAAASPTQKAGLSPAPALTAVVIAMIVFGIAKRK"
     gene            complement(29409..31067)
                     /locus_tag="PK679_03850"
     CDS             complement(29409..31067)
                     /locus_tag="PK679_03850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HPC55123.1"
                     /translation="MNARIAVILVLLVLVTQGCITTRDVVESPKNPMNITLGQAVGAI
                     NAELASVRTVNLASAERLSPVGLRGGEVEAVLSEKLVALPWAISSVTISSDGIIATAV
                     PATFRDIVGRNVNYQDAVRDALEKKAPRVSEVFMMEEGFAGISQSAPVFSPGGIYMGY
                     TDVTYRPETLIGRAVEPVIAATAYDIWVVQKDGRVIYDTTQEEIGKNLFSDPAYQSPE
                     LQAFFSRVVSEPEGRGVYRFWDRNWDRVITKEAVWATAGIDGAEWRVVLTSPGDEASP
                     AGAGLLPNASFQNLSNLDSFVRDAASFAREAGKDEALREFNDQKGRFSKGEWYIFAYD
                     MNGTVLALPYQQGLVGENRIDVRDSNGVEYIRAMVALASRGGGHTYYVYPNPSAGFSG
                     QLKLSSVVPVDDEWFVGSGVYLPHVDAGFSQKERDQLVQRVKKARDFAQQQGKEAALA
                     AFNDLSGPWADGASYIFAYSLNGTTLALPNQPGLMGTNRLGFLDHYGVAAVEWECDVA
                     ARGGGFVYVVYPNPGTGNEALKLCYVVPVDTEWFVGSGIYSTSA"
     gene            complement(31135..32058)
                     /locus_tag="PK679_03855"
     CDS             complement(31135..32058)
                     /locus_tag="PK679_03855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HPC55124.1"
                     /translation="MLYVVTGGAGFIGSHLVEALSLAGHELVVIDDLSSGRIENIASV
                     SANPRVRFVQGTVLDLGLLLEEFQGADGVFHQAAFVSVPGSIRHPLQSHEVTLTGTLN
                     VLLAARDTGVKKVVHASSAAVYGNLPGIPKREDMPVEPLSPYAVAKYAGEQYCRVLGL
                     LYDLPTVSLRYFNVYGARQDPASDYAAVIPRFIANLRNGKPPVIFGDGTQTRDFVYVR
                     DVVRANILAMERDAEGVYNIGSGKETSINELATILMRLLRFRGQPVYAGGRPGDVMHS
                     VADISRARSLLGWEPAFSLEEGLSDTLVSME"
     gene            32226..33443
                     /gene="ilvA"
                     /locus_tag="PK679_03860"
     CDS             32226..33443
                     /gene="ilvA"
                     /locus_tag="PK679_03860"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - L-threonine ammonia-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0006549 - isoleucine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HPC55125.1"
                     /translation="MVTLTDIQAAAGLLEGKVIRTPLVHSPTFSAITGAEVYLKLECM
                     QKAGSFKVRGATCRILLQRDEIGPGGVIAASAGNHAQGVAVAASMAGVPATIVMPTWV
                     SLAKQEATIGYGARVILAGESLEESIGFAQQFAMEQGLSFIHPYDDPMVIAGQGTIGL
                     EILSDLPDVECVVVPIGGGGLIAGIATALTASQRKIRVLGVQAEACPSAREALRAGHP
                     VTVEARPTIADGIRVKRTGELSFPVIRKLVDEVVLVDEEAIVNAVLALLERKKVLAEG
                     AGAAPLAALLSGGIRVSRGEKVAVVISGGNMDAFLLERVLKKGLYTGGRMVQIRVVLE
                     EGRGSLPALLDIIAKQGAVVSQIFQERSVPGLPVHQMRVTLELEVRDLPHRKGLIAAM
                     RSAGYPVEAFPED"
     gene            complement(33697..34230)
                     /locus_tag="PK679_03865"
                     /pseudo
     CDS             complement(33697..34230)
                     /locus_tag="PK679_03865"
                     /inference="COORDINATES: protein motif:HMM:NF027889.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide 5'-hydroxyl-kinase"
     gene            complement(35059..36009)
                     /locus_tag="PK679_03870"
     CDS             complement(35059..36009)
                     /locus_tag="PK679_03870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HPC55126.1"
                     /translation="MPGGFFSEWLGRYRHYLRMRNYSPRTIQSYEQVVRHFAYYVWLR
                     RNIDPQKLMVYWEDFSKARAETDVEVEPALFEDYLSFLSSMRTYKPKTMHRVISTLSS
                     FYRFLYSQGAVTTNPLIGVERPKIKGQELRYLKHSQVIRLIDSIEDPRDRLIVRTIYA
                     TGVRVSELCGMNIEDIDFEEGTIRVRGKGGKIRIVFVDPDTLSEMDRFIGSRIEGPLF
                     LGQMGHHISPRAVQHIFRKYAPEGITPHKIRHSYASELYRRSKNLRVVQENLGHTSIK
                     TTEIYLHTDLEERKRVYQEFFPLAEKSTKARENEADHDAS"
     gene            complement(36698..37642)
                     /locus_tag="PK679_03875"
     CDS             complement(36698..37642)
                     /locus_tag="PK679_03875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HPC55127.1"
                     /translation="MTFETFGLNEAYKRVQKVGDRLSEFESLIEWDQFRPLFADIYHN
                     NTRKGGRPNVDPVVMIKLLVLQSLYNLSDPELERQVTDRISFRKFIGFTTEIPDFSTV
                     WFFRERLIQSGKYEEVWNTFQAQLELKGLKITRGVIQDATIITADPGARSSDTSRGKD
                     GKTRRSRDGTWTKRGETPSFGYKFHALVDKEYHLIRRVETTSASVHDNQVDLSLPGET
                     VYRDKGYFGVKPRASINKTMNRAVRGRPLTIRENRRNRAISRVRRVIERSFAVIKRMF
                     HGGHVLVTTLGRVHLKNMFSAFSFNLVQLGTLKRKGAW"
     gene            38547..39680
                     /locus_tag="PK679_03880"
     CDS             38547..39680
                     /locus_tag="PK679_03880"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55128.1"
                     /translation="MVAWKAFFPMITVLFVDDEPALLDVSKLYLEKGGEIKVDTCYSA
                     EQALEYLRTQTYDVIVSDYEMPGMNGITLLKTVRNLGIETPFIIFTGRGREQIVIEAL
                     NSGADFYLQKGGDPRSQFAELIHKIRLAVERFRREGALEVTRYSVEKAGVPIFWFDSR
                     GRVLYANESGCALLGYSIQELCLLRIGDIDPFLSLPEWTQFVERLKSHERMTLHLIMM
                     TKGGQKLPLPVSFSCGEFGGKTIIFAYSYPRTGKEENEDWKKGLSSYRHMLADAIPGI
                     YMEVSPSGEIFFQNSTARVFFGPCDPVESRKRCTLFDLTVKGQHRSLAEVLSRIRLAG
                     EEELVELSLVRHDGTPCTLLFKTGVCPGPRGIDGTYFIESVPP"
     gene            39882..40553
                     /locus_tag="PK679_03885"
     CDS             39882..40553
                     /locus_tag="PK679_03885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5806 family protein"
                     /protein_id="HPC55129.1"
                     /translation="MRTHFGQDDVNKYRKFKKVDGATYNKVNQFLRKRTYITAREWAI
                     ARLCTDFRTRSGAEMTFIGQNLPRLVPFMQEPYSPQAVNQARNSFKKKVYKAGATFFY
                     GAMCGFFTSEELDDLLFEASEVARFLLEVERTSLEIDEEIEIEDRITEVMRSVGKAAA
                     HILNTRMQEDETGLPTGEGGESPLTRDTSDKRDAEPPRQPENVDREEETKPLQEGYGK
                     EEDPA"
     gene            40550..41314
                     /gene="mobB"
                     /locus_tag="PK679_03890"
     CDS             40550..41314
                     /gene="mobB"
                     /locus_tag="PK679_03890"
                     /inference="COORDINATES: protein motif:HMM:TIGR00176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HPC55130.1"
                     /translation="MKVIHVCGTSGSGKTTLIRSLIPLLADKGVVAVIKHLGHHVFAL
                     PEGKDTTLYLESGAKISAGIDPEKTVLVTDTVSLRTVLDMLSFSGTSFTIVEGFKSLP
                     MPKVVVGSLNDAHNVVLENPRPRDILDSLGRFPDYVSYYELTRDIWADGLIAVSGSLP
                     VDSSLLHPRERREFYDRFFPMIHDMTGKGAGVSDASRVRVHLYQGLFFGGEDRVIYAV
                     GSPTVEAVNSAVPRILERIEYMLKLALHTGRRDSCT"
     gene            41305..42660
                     /gene="glmM"
                     /locus_tag="PK679_03895"
     CDS             41305..42660
                     /gene="glmM"
                     /locus_tag="PK679_03895"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HPC55131.1"
                     /translation="MHLKKIEKRLFGTNGVRGIAGTEMTPGLALKIGLALGTMRQGTI
                     AVGRDTRTSGPALVSALKAGLLAAGCDVVDCGILPTPALQFLVRRHFDAGAVVTASHN
                     PPEYNGIKVVEPDGTEMGDEESVALEKHIFEDTSRIVSWERTGRERSAPALVEEYVDA
                     VVRAFPPCIGEGMPVVADPGCGAAAATTPEILNRLGCRVYSLNCQMDGTFPARPPEPS
                     AQGLLPLADLVKTTGASFGVAHDGDADRAVFVDEKGHFIEENVEFGLIADHVCQGRKG
                     VIVTPVSTSRIIEVIGKRNGCRVVYTPVGSIYVARTMISLAAQGIPVVFGGEGNGGLI
                     FPGHQLCRDGGMTAATMVSLLAHKGESLSSLVNAMPHFALIKDKFREKDPQALVARLV
                     DHYSGENLDLTDGIRINRGDSWALVRPSGTEPLVRVMVESESGERAEQFYKEIMSLIQ
                     R"
     gene            42820..43095
                     /locus_tag="PK679_03900"
     CDS             42820..43095
                     /locus_tag="PK679_03900"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HPC55132.1"
                     /translation="MKTIEIRITGRVQKVGLRNCIRHIAGKLCIKGEVMNLPDGSVKI
                     VASGDPLTLDKFSSMIYGCPRALIREMEICEIPFRSFADFSVVRPVE"
     gene            complement(43057..44058)
                     /gene="cas1"
                     /locus_tag="PK679_03905"
     CDS             complement(43057..44058)
                     /gene="cas1"
                     /locus_tag="PK679_03905"
                     /inference="COORDINATES: protein motif:HMM:TIGR00287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004520 - endodeoxyribonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043571 - maintenance of CRISPR repeat
                     elements [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas1"
                     /protein_id="HPC55133.1"
                     /translation="MESSEKSTRETVPWYVVSGFGAHIKATPKILIVQKRGCTQEIPL
                     SAIRHLLVMGGHTIHSSVISRLLSAGCAVSFFEADGEPLGFLRPYGFQYDQIVREAQV
                     RAFPHSTALAIAKGSAHARILYLVRLQEELDHPLFYEGELEILEKSVSELDYLVRLEE
                     VRRVHRLISDMYYEILARTVPAGLGFRRRTSRPHTDVVNTLLSFGYGLLFGNMCVAAI
                     GAHLDPDIGFLTRGKAGLVHDLCDPFRPSMIDDPVCSFVREGLPPGGFECGPDRCILS
                     DDLVQALLQRLIRTIRQDVIDSHVFALKESLMKKTDFIIHIPEPDSLNGAHDRKVSE"
     gene            44342..45634
                     /locus_tag="PK679_03910"
     CDS             44342..45634
                     /locus_tag="PK679_03910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HPC55134.1"
                     /translation="MFWDEKYETLSKKDLGRLQLKRLKKTLVQVQNVDFYRRLFKDAG
                     IRPEDIKSLDDVRKLPFTRKQDLRNGYPFGFFAVPLTKVVRIHTTSGTTGKPTVVGYT
                     KKDLRTWAGLIARNMTMVGLSDQDIFQNMVNYGMFTGGLGFHYGAELIGMTVIPSATG
                     NTRRQIEMIQDFGVTVIHCTPSYALHLAEVAEEMDARLDSLKTGLFGAEPWSDSMRRE
                     LEDKLGVTAYDSYGLSELFGPGVAFECRERDGLHIWHDCYLVEIIDPATGEVLGEGER
                     GEMVVTPLVKEAMPLIRYRTGDITMLYEDGCICGRGQKIARIMGRSDDMLVIRGINVF
                     PSQIEHVLLGIPEVGNQFMVYVDRVNHLDEMTIDVEINRDFFSGELKDLARIQNKVVK
                     ALRDALELRTTVRLVEPGSLPRFEGKAKRVVDRRKDTL"
     gene            45631..46935
                     /locus_tag="PK679_03915"
     CDS             45631..46935
                     /locus_tag="PK679_03915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HPC55135.1"
                     /translation="MTRAWDPRIEEMPLENLKKLQYTLLKTLVYRLYSFSAFYHRRME
                     EAKVHPDDIRTLEDIQKLPFMYKRDLRDNYPDKLFIASQEDLVRYHVSSGTTGKPTVV
                     GYTERDLENWTVSLARALVSCGLGRGDVIQVSYGYGLFTGGLGLHYGAERIGATVLPT
                     SVGNTERQIELMQDLGATAIACTPSYLLHIGEVAEKMGISIRKETKLRTGILGAEPWS
                     ENMRQRIQDWLGIKAYDIYGTSELSGPMFCECTEQRGFHVWGDLAYVEILDTKTQEPL
                     PPGERGEMVITMLQKEAMPLIRYRIGDISSIEEDVCPCGRTHPRVQRITGRVDDMLII
                     RGINVFPSQIEYALMTIPEVGQHFQIIVDRKGALDDMLVQVEVAPEAFSDKITDLMAI
                     RRKVEHKLRNILNVGVNVELVEPGSLPRFEGKAKRVIDRRKI"
     gene            46937..47371
                     /locus_tag="PK679_03920"
     CDS             46937..47371
                     /locus_tag="PK679_03920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HPC55136.1"
                     /translation="MGVNNFVIKQISVFSENKPGRLAAIARALQEEKINILAFSIAEA
                     DGFGVVRALVDSPQRAYEKLTKMGFNVAFTDVIAVQMKDEPGGLYEIAKILGQGGINI
                     EYAYAYSGKEGAVLILRVDNVEAAIAAVRKGGAKLLESSLFQ"
     gene            complement(47378..48697)
                     /locus_tag="PK679_03925"
     CDS             complement(47378..48697)
                     /locus_tag="PK679_03925"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine 5'-phosphate decarboxylase"
                     /protein_id="HPC55137.1"
                     /translation="MTETGKPDRTRKKGTILQVALDITEIDRAVQIASEAVAGGADWL
                     EAGTPLIKSEGMAAVRTLHAMFPGREIVADMKIADTGALEVEMAAKAGASVVCILAGS
                     DDAVIAEAVRAADLYGIRLMGDLISVPDPVARSRELEQMGVHIVNVHVGIDQQMSGKS
                     PLDVLSAIRDAIAIPLAAAGGLDATTAPQAAAAGADIVIVGSAITKSADVTASARMVR
                     EALDNPTLAREKRSLSEDIVRDILSSVSTPNISDAMHRKGAMAGIIPLCGEARMAGRA
                     VTVQGFAGDWAKPVEAIDIAEPGDVLVINNDGATHVACWGELATMSAMKRRLSGVVID
                     GAARDIDDIRRLGFPVFARAVTPNAGEPKGFGEINAEVRCGGQTVRPGDWIAGDASGV
                     VVIPRERAAEIARRALEVKKTEERIREEIRRGSTLSRVSDLIRWEKK"
     gene            complement(48752..49258)
                     /locus_tag="PK679_03930"
     CDS             complement(48752..49258)
                     /locus_tag="PK679_03930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HPC55138.1"
                     /translation="MNVGTTIIKSRHSVRKYKSDPVEENVIRDVLECARQAPTAMNLQ
                     PWLFGVVRERSLLEKIAGMTDHGKFIADAAVCFAIFGEKTAKYYLEDCCAATENLIIG
                     LWAYGVGSCWVAGDKKPYAEDIRKLLSVPAEYTLVSLVAAGYPAEVSMQKKKILDDVT
                     FFDTYSEK"
     gene            complement(49321..50313)
                     /locus_tag="PK679_03935"
     CDS             complement(49321..50313)
                     /locus_tag="PK679_03935"
                     /inference="COORDINATES: protein motif:HMM:NF024270.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3821 domain-containing protein"
                     /protein_id="HPC55139.1"
                     /translation="MNKIHIARLSGIPVLILLSLVLPAMAACGTIPAGDWVFIGEEGL
                     DITGTGVTAGSQIAYYGPGGSVSSVPAAQVTVADPSSFYVAPSVFLGKTGPWFTLPEN
                     NLAFYVGDPTIQVRIVDYTSGFVVGRDATWVPKGDIAGFRIDTNLWVFSHRKGCTGVP
                     LTIEITGPGGLSFSSLGGYRLGDVVVSTPTFESGPVWATGSGEYPIGDYIVSVRCEAN
                     NMHDNYPVTGKSQSEQVRFLLQKVNPLIATMTTTAVTETATAVTSTPGTTDRLESGTT
                     VETSVMTTVPSTAETVPPMLSARPTRAPGLLPATLFLALISAVLVLHQRRERQG"
     gene            complement(50378..51583)
                     /locus_tag="PK679_03940"
     CDS             complement(50378..51583)
                     /locus_tag="PK679_03940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HPC55140.1"
                     /translation="MTGTLRIVGTAHVSAKSVEEVRSAIEEFSPEIVAIELDPARYAA
                     LKKQARDPSVKDVLEAKNFTQLLVQWILAYLQRRIGLDMGVEPGAEMKAAIEEAEKRN
                     IPVALIDRDIGITLRRFWNSLSFFEKLKLLYALVLSLATVDSEEIDVEELKKEDVVSM
                     AMKEFRKFSPNGARALIDERDSYLAHNLAILKERHTRILAVLGAGHVAGVEKLLASPG
                     EILSKQELDADIRSRPWGKIFGAGVTALFILLLLAIAFSGVGMEVLFSALVYWVLLHG
                     ILTAAFTLAARGHPLSALTGFGVSWFTALNPLIAAGWFAAIVEAKIRKPTPADFRRVF
                     EAESFSAMMKVPLFRVVLVAALANLGSTLGTILYFIFIFPILGIDPTVLISQGFSNMW
                     NGITGLIPG"
     gene            complement(51580..52131)
                     /locus_tag="PK679_03945"
     CDS             complement(51580..52131)
                     /locus_tag="PK679_03945"
                     /inference="COORDINATES: protein motif:HMM:NF015639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC55141.1"
                     /translation="MTREDYRDEESTLAEQIVRIGFSCTRCGDCCRPGAGDDNLVMVF
                     PREIREISEFTGLEVTEVAEPYPDTVALPGNRIVTFGRVLRRFCGNCRFLSGSFCQVY
                     AVRPSICRTYPFMLEGSGLRVYPCRGLGKPISREDAVRIARDLLTRRAEEEEEIRRIQ
                     AVFPTIPPGPGRFIVDAEGVCRQ"
     gene            complement(52128..52691)
                     /locus_tag="PK679_03950"
     CDS             complement(52128..52691)
                     /locus_tag="PK679_03950"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase subunit A"
                     /protein_id="HPC55142.1"
                     /translation="MLPIFVVNNYGQFNHLILRMFRDLGIDARMVSNTLPPKEVAGSC
                     RGIVLGGGPDIGKCGNSPLFLHLGVPVLGICLGLHIIAREFGGSVAPGRMGGYGPVEV
                     ELVERSGILEGYPERILVWASHADEVTVVPPGFHLLARSGVCAHEAIAYPEKKIFGLQ
                     WHPEVSHTKDGQRVYQNFDAICREYGI"
     gene            complement(52795..53814)
                     /locus_tag="PK679_03955"
     CDS             complement(52795..53814)
                     /locus_tag="PK679_03955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00303 family protein"
                     /protein_id="HPC55143.1"
                     /translation="MPFVSDTFSLSPKQPLFAAVLANTMLSVVPGISGAGPSPEKTLF
                     TPILDAELVLRGRITSMPSRPDTPTGCPTPASITRAMMDMCGIIPLFINAGLVHHPTV
                     PCLDVYGEPGQDPRSADAVPRSADLFEEGRIIGAMLSRMCDVLVIGECVPGGTTTALC
                     VLRALGYPARVSSSYADNPVGMKEAVWEAVFRRIADHMPLSQLDAARFCGDPMIPLCA
                     GIGMGYGNRGRRLVLAGGTQMLAVAALMKSLSIPLPMIATTVYVRDDPSANFSEVANR
                     IGVPVAYVDPGFGDLGHAGLARYCIGEVKEGMGAGGAMFLAAIMGHSPHDIRKKILGT
                     VSSYQ"
     gene            54003..54446
                     /locus_tag="PK679_03960"
     CDS             54003..54446
                     /locus_tag="PK679_03960"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HPC55144.1"
                     /translation="MFDITGRLQEKGIDMENMLDAAMELYVPHGLSPEIARPRIGQMM
                     DRYMKDPNVASLLLAAVLLEDELYWKKKDSPIKDDPVFLLSDEIIGMAIAECIGGTYA
                     RFEFTRYDQKKPGVLRSLGPFLDDAVAGLIAGCTSRFYSECVLTP"
     gene            54434..55147
                     /gene="cobS"
                     /locus_tag="PK679_03965"
     CDS             54434..55147
                     /gene="cobS"
                     /locus_tag="PK679_03965"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HPC55145.1"
                     /translation="MNSLIALLQFTTILPLGGMRDFKDFARRSWLYPVAGYVVGGIAA
                     AGAFLIGPPLLAAAVGIGLVFLISGCNHLDGLMDLGDGLMAHGGCEKRVAALTDRQVG
                     TGAFALAIVVTLVSFSSLASVPSVAIALLIAEVGAKFSMAFLSTFGKPFRNGLHAIIQ
                     SQSRPYFPLLAGILCLPLVLLPVPPSTLLAVAAAMILCPLILQIIACRLFGGVNGDVV
                     GSANEITRAVILAVLCLSG"
     gene            55192..56073
                     /locus_tag="PK679_03970"
     CDS             55192..56073
                     /locus_tag="PK679_03970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC55146.1"
                     /translation="MPREIALHMRGGVITERDPQFCTIRTRIPAGMVNSQMLRGLADI
                     AEKFSAPGLHLTTRQTIEIPGIDSRNLQEIAAELDRNGTPIGSERDEVVNVTACPGLP
                     RCVFANIDSMNLAKAIDNRLFGREMPVKIRISISACPNACTSPMLNEIGIIGRISPIR
                     TPGLCTGCGTCVEYCKEGAISIKKGVSVLDPALCVQCGTCIRSCPFALLKSSGEHYMI
                     SVGGRRGRHPRIGRELVVVRTPEAVVDVVEKVVQWVYRRAWSGRLLSEQLEDIRFGQL
                     RDEIRNMLPASVLFEDV"
     gene            complement(56074..56211)
                     /locus_tag="PK679_03975"
     CDS             complement(56074..56211)
                     /locus_tag="PK679_03975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55147.1"
                     /translation="MKRGAVPDEALLNAQLQFNQLIRDGESIECGDEKNTGFVPRYRI
                     R"
     gene            56559..57836
                     /gene="tuf"
                     /locus_tag="PK679_03980"
     CDS             56559..57836
                     /gene="tuf"
                     /locus_tag="PK679_03980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor EF-1 subunit
                     alpha"
                     /protein_id="HPC55148.1"
                     /translation="MAAEKPHMNLAVIGHIDHGKSTTVGRLMFETGTVPAHIIEGYRK
                     EAEAKGKATFEFAWVMDNLKEERERGITIDIAHKRFDTPKYYFTVVDCPGHRDFVKNM
                     ITGASQADAAILVVAAPDGVMEQTKEHVFLARTLGIGQLIVAINKMDMAKYDQKRFEE
                     VKKDLSALLQMVGYKPAETLFIPISSLAGVNISKKSPETPWYTGPTLLEALDTLKEPE
                     KPVDKPLRLPIQDVYSISGIGTVPVGRVETGIMKKGMKVSFMPANKEGEVKSIEMHHE
                     EIPQALPGDNVGFNVRGIAKGDLRRGDVTGPADAPPTVADEFTAQIVVLQHPSAITVG
                     YTPVFHCHTTQTACTFIELKKKLDPRTGQTKEENPTFIKTGDAAIVQVKPTKPMVIEN
                     VKEIPQLGRFAIRDMGSTIAAGMCIAITPKQMR"
     gene            57875..>57993
                     /locus_tag="PK679_03985"
     CDS             57875..>57993
                     /locus_tag="PK679_03985"
                     /inference="COORDINATES: protein motif:HMM:NF012558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uS10/mL48 family ribosomal protein"
                     /protein_id="HPC55149.1"
                     /translation="MQKARIRLTGTDFKKIEMVCDRIREIAERTGVNLAGPIPL"
BASE COUNT        12993 a        16185 c        15809 g        13006 t
ORIGIN      
        1 catcctagga gactgggggt cttctgacct gcgttcaaat cgcggtggcc ccatgaacga
       61 tactttttgg tgcagccatg agatgggatc cgcgctgttt cccctgcctc ctctcgcgtg
      121 tctccctcga gtgcacactc tgcaacgcag acccggctct ctccaggaga gtccgggatg
      181 aatgtgaacg gatgctcaac gacctcaaag agaggcccct cctgcacccg gaggttgcaa
      241 gcgccctcca ccggcatgca tacgggatgc tcgggacgcg ggaccccttt tccgccctca
      301 aggaagagag cacgaaaaag gctctggagg tctgcaggac ggtcagaccg cgcttaaagt
      361 ctttccggga cttcgtgaca gcggctgtca tcggcaacac ctttgatttc ggagtccttt
      421 cccattccgt tgaaccggac tttgcgcgtt atttcgagca tgaatttgca gaggggctct
      481 tcatcgacga taccgaccgg atcctgccgc tcacggaccg cgtcgtctac ttcaccgaca
      541 attgcgggga gatcgtcttt gaccgcctcc tcgtcgagta cctgtcccgg cggggatcgg
      601 agatcacggt tgccgtccgt gacgaaccga ttctcaacga tgccacgcgt gccgatgcga
      661 atgatgtgca catggagaag tttgcctccc tcgtcaccac gacgggatgc gggtgcgaac
      721 ttggtgtccg tctcgactgc atgcccgatg accttgcccg ggccatggac acctgcacca
      781 tcgtcatttc aaagggaatg gcaaattacg agtcactctc cgaatacagc aggcttcccc
      841 cggttgcata cctgatggcc gtcaagtgtg accccatcgc ggacgaggtg ggcgtccccc
      901 gtgggaagaa agtggcaatg ctccgggtga attgagagaa gagatccccg gctaaaaaac
      961 tgtttttttt tggagggtac cctcacgctg tcatccggat gctcgatacg accgcaaaca
     1021 gcatggcccc gagtatgaca acggcaataa ctgctgcaat cacgatggca acaatcatgg
     1081 caatggcagc ttttgtatcc gatacacctt gtagttcgcg gatcccgata accccgagca
     1141 cgatcgacca gataccaccc acgattatgc cgataagggg aatccacccg agaacgaaca
     1201 ccggtgtgag agagtagaag acggcctttt ccgtctgcca gacacctttc ctgccaccga
     1261 cgaggtacac gaagatatgg aggaagaggc cgaagacaac tgccatgata agagtgaaca
     1321 cgaggataac gactatcagt gacacgatca ggagcgcttc agccggaccg ggatggaaag
     1381 aggagagtac cgcaaagggg tgaatggaga tctcaaggac ggtcaggagg gtacccatga
     1441 gggaatagaa tacggcaagg atgatcaggt aggtaatagt atctcccgct tcctcgtcct
     1501 ttgccctccg gaacgagagt gaggggctga agaggaaacc acgtatcttg ttcaggacag
     1561 actcgctcat agtgcacatt tttcgaccgg gaaaaatttt aagttaccgg aatactccgc
     1621 ccggaatggc tgcccgtttc cctgccggaa cgcctacttc ccgactttcc ggaaataaag
     1681 cacttttccc cccggggtgg tggtattttc ttctcatcag gcaatagttc ctttatggtc
     1741 gagctggtag gcctctcgtt tggctggatc ctgatcatcc ttggaacgat cttccttgtg
     1801 atcgaggcct cgaacccggg cttcttcatc gcggtaccgg gaacagtgat gatcatcctc
     1861 ggggcgatga tcctccttgg agtcgatata ttctccgggc cccttggact cgtcgcaggg
     1921 gtcatctccg cagttatcgt ctcgctcgtc acgatctggc tgtaccgccg gatcaacccg
     1981 ggggatgccg ccccggtgac gatcagcagg gattcgctcg tgggcaggga agggcgtgtc
     2041 atccgcaggg tgactcccgc ggacctctcc ggaaaggtcg ttgtgtccgg acaggaatgg
     2101 agtgcccgga gcagggacgg cgagattccc gcgggcgcga cggtcaggat tatcgcgtcc
     2161 gagggggtcc acgtggttgt tgaaaaggtg tgatacacat ggcagttatc gagacgcttg
     2221 taacgttttt cctgatcatt gcgatcgtga ttatcttcgc ccggggggtt gtcatcatcc
     2281 agccctacga gcaggggctt gccatcaggc tcggacgcta taccggccgc atgaatcccg
     2341 ggttccgctg ggtttttccc ctgatcacga acgtcgtgaa gatggatttg cgcacgcagg
     2401 tcatggatgt accttcgcag gaagtcatta caaaggacaa ctcgccgacc aacgttgatg
     2461 ccatcgttta catcagggtc atagacccgg aaaaggcatt tttcgaggtg gccaactatc
     2521 ggatggcaac ggttgccctc gcccagacga gcctccgcgg tatcatcggc gacatggaac
     2581 tggacgagat cctctataac cgggacatca tcaacacgaa gctccgggat atccttgacc
     2641 gggagaccga ccagtggggt gtcaaggtgg agcgcgttga gataaaggag gtggatcccg
     2701 tcggggctgt caagcaggcc atgacagaac agacggctgc cgagagggcc cggcgtgcgg
     2761 ccatcctgcg tgcggacggc gagaagcggt ctgccatcct caaggcggag ggaaccaaga
     2821 ggagcatgat cctcgaggcc gagggtgacc gtcagagcaa ggtcctcagg gctgaagggg
     2881 aacgtatctc tcgtatcctg caggcacagg gagaggcgca gtcgctgcgc atcctctcgg
     2941 tcggtgcacg gcccctcgac cgcagggcga tcactgtcct ctcgctcgat gcgctcaaga
     3001 ccatggctga cgggcaggca acaaagatca tcttcccgtt cgaggtctcg accctcatga
     3061 agcaggccgc acggtttctg ggcgcatccg aggagggcgg tggtggtgag gagggaatgg
     3121 cccccgcagg cgtccctgaa gcagatatcc tcgggacaat cccgacagcc gacgaggtga
     3181 aggagatcct tcgggagatg gacacctcgg tgaagacaga gatatcggtc gaggatttaa
     3241 aagatatcag caggacgagg aagaagaccg gatccgaact cgtcgacgag atcgagaagg
     3301 acgcatccac catggactga cccttatccc ctttttccat ttgtcatttc tggtgtgtga
     3361 agggcagggt ttctttccag cctcccgcaa ggccggggct ggttaatcca ataaaggaat
     3421 gccatttttg tatagaattg atcaggagga gtgccgccgg gacgtgggct tcagcggcgg
     3481 cggggcaatc cttgtgcgag ggtgcggggc gaccagtccc tccttcgatt ctcacgacct
     3541 gctcaaaaca gcagggagca ccttttcgct ggataaaaaa gccggctccg atggagtagc
     3601 gataaaggat agacgagagg gtttttctga aaaaaccttc ggtactcttc cggagcaatg
     3661 agtgacggga aacccggtca gatcttttcg accgttatcc tgacccggtc cccggcgcgc
     3721 acaccatgcc ccttgggtac atcgatgttg aaccagaggg ttcccggttc gtcctgcgtc
     3781 ttgtcctggg acatgaggca gtccttctcc ccgttgatat cagccacaaa ctctatgacc
     3841 gattcgaact ggatgaccgt gctcatggaa agatgaatgg aggtcctatg gatcctcctc
     3901 tataccgacc tggacgtcac catccaggtg gtactgtttg aatagctcca cttgatgatt
     3961 gccagttcct ggcagatctc ggagaggatg gccatgttgg tccccacctc tttgggtgaa
     4021 agaccgagtt ccctggcgat atattttgat ttgaagtaga tttttccttt ctcgagacct
     4081 cccttgaggt actggacaat tctggcctgg gtctcattat agcactgcct gatattgcgt
     4141 gaagtgttca cgtccattca cctcagccgt ggtagtctgg tacactttac gtctataaat
     4201 atatacccat cgcgatcggt tcgaacaaag gctttaatga gggagcatca caaaattcgg
     4261 cggattataa tggcattctc gacacttacc taagggaaag acgttgcatc ccggcaaaca
     4321 ggatgattaa agggattatg ccggcattcc ggtcttgaca cgggatattt tggcgatgag
     4381 cccgttcagg acctcttccc gcatgccctc cacgaacttg atactgccga cgacgaggtg
     4441 ccccccgccg gagatacccc cgccggggat ctcttcccgg agctcccgca ccatctgcgg
     4501 tatattcatc atcacgcccc ttgaccggag gacggcaaag tcgggcccga acccgatcgt
     4561 gaccacgggg gatcccgcgt gctgctggca gaggcggtcg tgcacctcac cggatgtctt
     4621 gccgggtggc gggaaggtga acttgtgggc atggatctcg acatcgatga ggaagagttc
     4681 ggcaccgttt tggagcgtct ggtggcggac gtgcggcatg catgcactca tctggtcctg
     4741 tatcgcgagg tttgcaccct ccacgaggtg cgcaacgagt ttcccgtgcc gttccgtgtc
     4801 acccgcaagg ttgaggacat ccttgatgat ctcccgcccg tcgttgaacc gcagccagaa
     4861 ctgctggtag tcgagggcga gggcgatgtc cctgcagttc tcctcggtgt aggtgtcctg
     4921 cacgagggca aggtacctgg cgcgttcggg cgcctcgctc ctgtccccca cccctgccac
     4981 ggcaggaagg tgcctgatga ccggttcgac ggccgggttc acgaggcggg ccacctccgt
     5041 tccgagcatc ccggccgtga taccgaagtc cccgccaaca tggtaggggt tgacgtgccc
     5101 gaccaggtac tggtccacta ccgcgtccgg gtggtggtgg tcgatcacga ccatggaaag
     5161 atcgtacacc tgtgccatct tcatcgaggg cagatcctct tccgtggacc cgttgtccat
     5221 caggatcacg agcggcatct tctgcccgta ccggacgttg tccttcgtgg cgaaatcaag
     5281 gtcccggatg atgtcctcta tctcgtagaa aggagccttc gagggggcgc gtttgaagag
     5341 gaaataatcg gcatcgaagt ctgcgcctga ttccctcatg agtgcaatga ccgcctgctc
     5401 gatggcaact cccgcacata tcccgtctgc gtctgcatgg tgacgcagga ctatcggctg
     5461 ggacgtaaaa acggctctcc ggatgatctt tgcgaccttt cgcatctccg gcttcagctt
     5521 ttcgagtacc ggggattcga tcaggagcgg gatgtcaggg ggctcggaac gaatgtccag
     5581 ggccttctcg atccgctccc tgaccgcctc ggcatccttt ccggcaagga tggtcaggct
     5641 ctccacctcg atctggagct ggttctggcg catcatcacc tcgccaacga tcctgaccat
     5701 atccccgcac tcggcttcgg ggtacgcccg cacgcctgcc tcgacgaatg cggccgcgtt
     5761 ctcggtcccc gattcgtcca cgatggtgaa tatggtcggg ccgctcgtct gcttgatctg
     5821 ggcaatctct ccctctatcc tgaccgtctt tcccaccttg cccccgagtt cggcgagccg
     5881 cacggcagtc gacttcttct ccaccatctc gacggtgtag accgggattg taacctcttc
     5941 gaggtcgatg ttcccattgg tgcggatgtt gagcaccctg acgaggatgc tgtcacgctc
     6001 cttgtgctgc gtgcgcacgt tgctcttgtg gacaagtccc tttaccctgt cgttcagctg
     6061 gacgaaggtg ccaaagttgg caaagccctg gacacgcccg atgtaggtct ttcccacttc
     6121 cacatccccg aggtcacatc ccgggctcat gcggtatacc gtgatattcg cctcattcat
     6181 attgaccagc gggcgggaca acgggggacg atcccccttg cgaacccgtc cggactcctc
     6241 tgaatatatg aatgcgtccg gaactcttat gtatgtatgg aatgattccg ctctttcctt
     6301 ctcattccct gctgtccttg tacggtacct cgatcatctc gagatctgac gggatgatca
     6361 ccctgcccgt gaaccgtgcc tgtgcgtccc gcatgtgacc ggcaaccgtg gtgtatcgcg
     6421 aactgatatg gacgagggca agtgtcccgg ctccgaggaa tgcggcagcc tcgccggctt
     6481 ctcccgcggt tgaatggagg acctcctctg ccctgtcacg ggccgaatcg tcgtacgtgg
     6541 cgtcatggat gaggagatcg gcaccccctg ccacatcggc aatccggctg tgaacgggcc
     6601 gggtgtcccc ggtatacacg atctttcttc ccggccgggg aggccccatc acctcgtccg
     6661 ggcgaacctc gacggtgtca ccattcctca cgacgcggac agtttctccc cgctgcagcc
     6721 ttccgaagag cggcccgggc gggactccga gatcgatggc cttctgcctg ttgaaccgcc
     6781 cggggcgcgg gtcctcgcag aggacgtacc cgagtcccgc cataccgtga tccgttccga
     6841 atgccctgac cgtgtagccc tcgaaccgga cggcggaacc cgggcggagt tcgacaggaa
     6901 tgaccgggaa cctgatattg taccgtgcga ggctttttac tgccgctgca acctcggtca
     6961 cccattcggg tccgtaaatc gtcaggggtt ctgtcctgcc catgaacgag agcgtctgcg
     7021 caaggccgaa gatcccgagg aagtggtcgg cgtgccagtg ggtgatgaag attccatcga
     7081 cgaggaaacc cgtccgtgct ctcatcatct gttgctgggt cccctccccg cagtcaaaga
     7141 ggagagtgtc gtgtcccctc cggaccatga tgcacgacgg gttccgcagg ggcgtgggaa
     7201 gcgctgcagc ggtcccgagg aaatagacat gcagagtctc accgctcatt cctgccaccc
     7261 ccggacaacc gcaagactcc gcttcccttc tgcaacgccc ctgccctcga tgaccacgac
     7321 acccgcaaaa ttacgcccga tgaccggccc gacagcctcc cagtcaacac tcccgtcccc
     7381 gataggaaga tgctcgtcgc tctgcccgtg gttatcgtgg acgtgcatgt gcgatgcccg
     7441 tgaaacgagg ggcaggaaat cacggacgag tcccatggta tgggcatgac cgatgtcaat
     7501 cgtgatcccg acgcccccga taccctctgt catgccgagg agttcgcccg ggtcccggca
     7561 gaggaactcc cgagccccga tcatgttctc gaggcatgcc acgacaccgt gatccgaggc
     7621 gacctttcct atctcccgga gggcaacctt ctggaactcc cacacgcggt cgggcatgat
     7681 ctttccgacc ggcgagatgt aaccgggatg aaccgttacg cgatcggtcc actccgatgc
     7741 ctgttcgatg cagcaggaga cctgccggac tgactctctc cagatgggat ggttgagcgt
     7801 ggcgaggttg aggtcggcat agggggcgtg gactgttatt ccaaggtgcg ttgacgcgat
     7861 tgcctcgtcg atccggcgga cgttttcggg gttgtccagc ctgtagctgc catctgcaac
     7921 gatctcccac ccatcgaaac ccgcctcctc gatgccgtat atccatgaga tatcgtccca
     7981 caccttcgag gacgacgaga aatagatgcg aaaactcatg ggtcctccgc gatcttccgg
     8041 agaagggccc gggttgcccg gacgaactct tcgagcgttc cctcgttctc aatgatatgg
     8101 tcagcaccgg caagggcgcg gtcaaggccc caggcgagct cgcgctggtc ccgctcctcg
     8161 agcgcccggg gggtgtcctg atcgtcctcg cgtcccctct tcgccagcct gaccgcccgt
     8221 tcagaaaaag gtgcccggat cccgacgagt gcaaaacccg gaaaagcttc ccggaacagc
     8281 cggacctcgg catccccccg tatcccgtcg acgaggacga gccttgctcc ggttgccctg
     8341 atcctcggga tacagcggcg ggcaatggca tccatgcccc cgttccggcg cagctgctgc
     8401 gccacggcac cgagattttc gtcggtcggc ggaagcccgg ctttccgggt ctcctcgcgg
     8461 atgaagtccc ccatgacgac taccgggatc cccatctctg ccgcaaccct tgaaaactcg
     8521 cccttaccac ttgcagggaa cccaacgacc ccgatcacct tcatacatca cctcccctgt
     8581 ctcccgggtc cggatccgga ttgtcctgcc aaccctgacc atcttcgagg cgagtgccga
     8641 gagctcttcc agggacaggg gcgggcgggg accattcacc tcttctgccg aaaggtaggg
     8701 ctttcctttc acctcgcggg cgagtgtcca gtccttccag aacctcttgt gcacgccctg
     8761 ctggagcacg atcgtccccc gcgggagctc cttttcgatt gcaagtatct ccctttcgtt
     8821 cccccagaag accgtcagaa ccacctcgaa cgaggggaga atgcctgcga catgggcgtc
     8881 ctggcagagg gcaaccgatt ccctgacctg ccgcgtgtaa tcttccctgc agacgttccc
     8941 gtatccttcc cagcgcttgg aaaatccctc ccaccggctc ttgtaatcga gcgccacgcg
     9001 gtccacgagg cgctcggaaa ggagctgccg gatggtctcc ggaaaataac cgttcgtctg
     9061 gatccccacg aggaggccca taccgcgtgc agcccgcgcg agggcgacga gcggttccct
     9121 ctgcatggtc ggttccccgc cggagaagac cactcctgac acgagggggc ggacacgtgc
     9181 aatcttttcc accagccacc cgacctcgcg catgtcactg ccggtctgga tagccgcgtt
     9241 gtggcagtat gagcaccgga gggggcaccc ccggagaaag accgtgcata cagccctgcc
     9301 cggccagtca atggtgctca ggtcaacaaa cccgccaaaa tttacctgca cccgtgtcac
     9361 cgctctatag taataaaccg ggaagtttca tcaatctatg gtaccctgca tggatggcag
     9421 ggcgactctg ccgactcccc ccctgtcccc ggatgcccag cctgcgattt ttcaatccag
     9481 tttgattcta cacaaatcaa atttaattgt tatcaaaaca agccaatttt agtctttgat
     9541 ttgaaaaaga accttttatc ttgtctttct tcctattact tcccatgagt ctgatcgatg
     9601 acgccagggc aggcaggata accgaagaga tgcgtgtcgt ggcaaagcag gagggtgtca
     9661 cagaggactt cgtgcgccgg ggtattgcag ggggccatat cgtcatcccc gtctccccgt
     9721 acaggaaggt caggatctgt gggatcgggg aggggttacg gaccaaggtg aacgcatcca
     9781 tcgggacgtc gaccgatatc gtggacgtcg acatggaggt ggaaaaggcc cgccaggcag
     9841 agagggcggg cgctgacacg ctgatggagc tctccaccgg gggggatttc gtcgagatac
     9901 gaaagagggt tatcgcggcg accacgctct cggtcgggag cgtccccctc tatcaggcct
     9961 tcatcgaggc tgccagaaaa gacggcgccg tcgtccatat gaaggaagac gatctcttcc
    10021 gcatcacggc cgagcaggcg aagctcggga ccaacttcat ggccatccat acgggaatca
    10081 actgggaaac cgtcaagcgc ctgcgcaacc agggacggca tggcggtctc gtctcccgcg
    10141 gcggggcctt catgacggca tggatgctcc acaacgaaaa ggagaacccc ctctactcgg
    10201 agttcgacta tctcctcgag atcatgaagg agcacgaggt cacgctctcc atgggtaacg
    10261 ggatgcgggc cggtgccgtc cacgatgcaa ccgatcgtgc ccagatccag gagctcctga
    10321 tcaactccga gcttgctgac aaggcacatg cagaaggcgt gcaggtcatc atcgaggggc
    10381 cgggacatat tcccatcgac gagatccagg caaacgtcgt cctccagaag agggtcagta
    10441 accggaaacc cttctacatg ctcggtcccc tcgtgaccga cattgcgccc ggttacgatg
    10501 accgtgttgc tgccatcggg gcatcccttt cctctgcata cggtgcagac ttcatctgct
    10561 acgtcacccc ctccgagcac cttgcgcttc ccacacccga agaagtctac gagggagtca
    10621 tcagctcgcg cattgccgct catgtgggtg acatgatcaa gctgaaaaag agagaggcgg
    10681 acctcgagat gggtcatgcc cgccgtgacc tcgactggga gaggcagttc cagatagcga
    10741 tgaacccgga gcgggcccgc cagatcagga gcgagcggat gcctgccgat gccgatgcat
    10801 gcacgatgtg cggggattac tgcgcactca agatcgtgaa ccggcacttc agcttctaaa
    10861 ccatcttttt tccggaatga cccggacgaa ttgctgattg cccgtctttg aacccctcac
    10921 cacgggggtt gtcaggggga ggggttttcc cccctgcgcc agacaaaaaa ttcccctact
    10981 tttctgcatc cgaaattgcc agctggtaca tccagtcgag gaggcgggga cactcctcga
    11041 cccggcactc gaggtcacac cctatgcacg ggatgagttc gtcccctgcg aggaggtgcg
    11101 ccgggtcgac cgggcagcgg accgccttga ggacaaatgt tttgatacct tccttccgga
    11161 actcgattcg ctcgatcagg ccgtcatcaa gcagcttttt gacgagccgg gaacacttgc
    11221 ggctgtcgac atcgagtatc ttccaaaggt cactctgcag gacaccctcc gggtgggact
    11281 gtatcacctt gagtgcatct tcgggggtct tggtcatatc tcggacagtc ctgtgagata
    11341 tttcaggcct gcggctggat ggaaaggata ttgttgccac ggatgacaac ggttccaagc
    11401 gtccttcccc gcacgttgtt cacgtactcg gtggtgtcat ccatgtggat gttgaggtat
    11461 tcgtcaacgg cgacaaggcg tccctggagc ttgcgctgat cgtcctttat ctccacgata
    11521 atcctcgaat ccaccagaga aaagaccttc ttgataggta atacgatacc gttcaccatc
    11581 tgcaccttat tggggactgc cggtatttat tggttttcag ccgggccact gccggaaaaa
    11641 aagggggggg atgctgcctt tggtactact ccccgatcgg aacccaccgg ttcttgaggg
    11701 tcttttcgac tgccggaagg gtcgtatact ccatttcgga cagagagagg cggtgcggtt
    11761 caaacggccc gtgcgcccgg aggatatcgg caagttcgtt gcatctcgcc ctgacccggt
    11821 cgaatgcagg gtcgtcgaac atgtctgcag ggccgatcag tttcccgtta cagacctgga
    11881 aaccaaggca gatgacacgc gggggcccgt caaaccgcgt gcagtttgca tccggcaacc
    11941 cgacaggcat gaaggggccg tggtgggatc cccgcatcca gccggcaacg atgataggag
    12001 tggcaaaggg gtcgatgatc tccccgacag ccggaaggcc actctggccg cggacaatca
    12061 tgacggggtc atccttgccg acgtacttgc cggcgatgag agagagcctc tgcgtgctcg
    12121 tggacgcagc gataaccccg tccttcctgc ggaccgactt gatgacatac cgtgacggtg
    12181 ccccgatgta tgcaaggagg ctgtagctct cctccggggt ccggaactcg atcttccgct
    12241 tctcgatgac atcgtgaacc tcgaatatga agccctcgtg catcgagggg tcgatgacga
    12301 gccctgcggt attgaacggg tctgcgaaaa tcttgtagag gtagaagttc catgccccgg
    12361 gttctgtctt gtccgccatg aagaggagaa ccgggtcgga cccgcgttcc tcgaactcca
    12421 tctccgcgac gcccggtccc attcccttca cgttacccga gaatgcatcg gacaggatat
    12481 cctgtccggc gccgtagagc ttcatctccc tggccatctt tgcgcattcc tggaacactt
    12541 tccaggccag ggcatggatc tctttgttat cctcgccgcg ggtatgcgtc attatcagtt
    12601 cgaggtcatc accgcagtgg gtgacgaaag aatcgatcag cagctttcct tcctgttcct
    12661 tgagcagccg ggcagctttt tcaagaatga cagggtgtgt gcgggaatgc cccggaaaac
    12721 tcccgatatc tgctttgatc agagaaatag tggtttttgg catgaaatta ccctcgagtg
    12781 ttatacacac atagtaaggg gacgggaggg taaaaatgtg tgtgtttttg aaaatcccct
    12841 ctgccccttt tcattcctcg cgaggggcgg gggggttacc ggtgccgctt gtttccatcg
    12901 gaacgtagga tacttccaat actccgtgcc gatacgttac ctgttccgaa cctgcccggg
    12961 gcggcgggac agctgcactt gtcctgtact gtctctcccc gtcctttccc catataaaga
    13021 ccctgtcacc ccggaagagg acctggacgt tctccggtga gagtcccggc agctcggtga
    13081 cgaggagaat gcggtccccg attctctgga tctcgatatc cggctctttc ccatcccccc
    13141 tcgcacgctg gggcgggacg gggaatccgc cacccgggga gatgatcaca ttcattccga
    13201 cgaagacagg ctggagccgc ccgtcgtggg cagccgctat caggtgcctg accatctcct
    13261 cgagtgtctt tctgggatct tcctgtcttt ctgtcattgt tcgtaaccgg tgtttttcct
    13321 tcctgcgcag agcgggtcct ttccattccc gctctttttt ctcaggcttt cagctcttcc
    13381 tcgagcaggt gcgtcaacct cttgatctcg ttccagtctt tcttcctggc aaacgtcgcc
    13441 ttgcggagcg gttcggtatc gtaggtcctg ccggtcctga tctctgcctg tttgagggct
    13501 gcaacagcgt tctcgaggat cgtccgctgc tcctggttgt agaggatctc ccacgccatc
    13561 cgttcagccg cctcgagcga ctcgcggtcc atcgagcctt tgaccttctt aagagcctcg
    13621 tcgaagtgtt tcctcgagat ccggacgttg accacggcat cggcaatctc ctgctcgctc
    13681 tttccgccca tcacactgat gaactcgcgc atggcgcaga gcttggcctc gcggacgagg
    13741 gcctcgatat ctgcaccaac gtacccttcg gtcactgcaa cgaggtcatc gatcttcaca
    13801 tcgcccgtga caagttgtcc cccgctcccg aggtagacct caaagatctt cttcctgctt
    13861 tcggcatccg gcggcgggac gtagatatgc ctttccatcc ttccgggacg catgagtgcc
    13921 gggtcgagca tgtcgggacg gttggtggca ccgatcacgg tcacgttctt gagctcctcc
    13981 aggccgtcga gctctgtcaa tatctggctc acgacgctct ccgtgacgtg ggaggatccc
    14041 atgtacatcc ccctcttggg gacgagggcg tccacctcgt caaagaagat gattgccggc
    14101 gaggcctgcc gcgccttccg gaatacctcc ctgacaccct tctcggactc tcccacccac
    14161 ttggagagga gctcgggtcc cttgaccgag atgaagttgc actcgctctc gtttgccact
    14221 gcctttgcaa gcagggtctt tcctgtcccc ggtggtccga agagaaggat cccctttggt
    14281 ggccttgtct ggagcttctc gaagacctgt gggtaccgca ggggccattc cactgcctcg
    14341 cgcagctcct gtttcacctc gtcgagaccc ccgatgtcct cccacgtgac gtccggaacc
    14401 tcgacgagca cctcgcgcat ggcgctcggt tccacgtgtt tgcgcgcttc ctcaaagtcc
    14461 tctttcgtga ccttgagctg ctccagcatg tcagccggga tctccttgtc gaggtcaagc
    14521 ctgggcagga ccttccggag ggcatgcatt gctgcttcct tgacgaggag ggcaatatct
    14581 gcgccaacga acccgtgcgt tgtttcggcg tagtcgtcga gccggacgtc atcggcgagg
    14641 ggaactccac gggtgtggac ctggaagatc tcgagcctgc ccttcttgtc gggtatccct
    14701 atctctattt cgcggtcgaa cctgccgccg cggcgcaatg ccgggtcgat tgcatcggga
    14761 atgttcgttg ccgctatgac gatgacctgc ccccgtgcct tgagtccgtc catgagcgac
    14821 aggagctggg ccacgactct cctctccacc tcgcccttcg tctcttctct ccggggtgcg
    14881 atggaatcga tctcgtcgat gaagatgatg gccggggcat tctcctgggc ttcctcgaag
    14941 acctcgcgga gccttccctc gctctccccg tagtacttgc tcatgatttc agggccggat
    15001 atcgagatga aatgcgcgtc cacctcgttt gcgacggcct ttgcgatgag ggtctttccg
    15061 gttccgggcg gcccgtagag gaggactccc tttggcgggt ctatcccgag gcgctcgaag
    15121 agctcggggt gacggagcgg gagctcgatc atctcccgga cgagttcgag ctcgcgggtc
    15181 aggccgccga tatcctcgta gtggacgtcc gttatctcgc ccttcttcct ctcttcgggt
    15241 tcgtagggtg tctctttcag ctcgatctgg gtatcctcgg tcacgatggc aattcccttc
    15301 gggctgacct tggagatcac gagcgtgagc ggatttccga tcacgtcaac ccggaccgtc
    15361 tgtccttcca tgacggcgcg gcccctgagg atacgcgaca ggtactgttc accgccgacc
    15421 agccggatag gctgggttgg gttgatgacc actttctttg cgtatccaac ctcgactttg
    15481 cggatcttga cccgctcatc gacacctgtt cccgcattgc tccggatcgt gccgtcgatc
    15541 ctgatgatgg cctgaccggt atcctgggga aatccgggcc agacaatagc ggtcgccttc
    15601 tttttgccct gtatctcgat ggcatcgcct gatacaaggc caagcttccg catggcctcg
    15661 atgctcagcc gggcaatacc ccgccctgcg tcgtccctcg ctgcctcctt gacaatgacc
    15721 tcgatggtat ctgaatctgc catattcatg tgctcccttg gtaatcgttt tcaaacattt
    15781 actaaaagta agtgatttgt attatataaa actacctctc ctgccatttg ctaataacca
    15841 cccggaaaag tctccacaac actgcaataa gattttgatg actgcaacgg aattttcccg
    15901 gtaacagcca ccggtttccg ggagccgtcc tcacgcaccc cgttctgacc cgtaaagaca
    15961 atggtccctg ccgtccaaga aaagaaggac aagatcgccg gtggcataag aggggccgca
    16021 gatgctggat atcaggttta tacgggaaaa cccggaggtt gtccgggctg acctccgcag
    16081 gaggggaagg gacggcgacg tccggatggt cgatgacctc ctcgaaaagg acaggcggtc
    16141 aaggacgctg aaagtggaga tcgacaagct caggcagaga agaaacagca tcgcccgtga
    16201 aatcaacgag gcaaggaagg caggccggga taccagcgac ctcctgcagg aggcttcacg
    16261 tttacccgaa aaaattaagg aactggaaag cgtcatcgag agcctctcca gcgagatcac
    16321 gggggtcctg atgagcctgc ccaacatcct ccacgagagt gttcccatag gcagggatga
    16381 ttccgaaaac ctcgaactgc gccgggtggg caccccgcgg acgttcgact ttcccctccg
    16441 gaaccacggt gaacttgcag ccgagtgcgg ctgggccgac ttcgagaggg ctgcccgggc
    16501 tgcaggcgcc gggttctact acctcaaggg aagccttgtc ctcctcgacc ttgcgctcca
    16561 gagatttgct atcgaccttc tgacgaagaa agggttcatc cccgtgatcc ccccctacat
    16621 gatgaaccgg tcttcctacg agggtgtgac agaccttgcc gactttgaaa acgtcatgta
    16681 caagatcgag gatgacgatg catacctgat tgccaccagc gaacatcccc tctgtgccat
    16741 gtaccaggac gagatattcg aggaacgcga cctcccgctt cgcctgtgcg gggtctctcc
    16801 ctgtttccgc agggagattg gctcccatgg ccttgatacg aaggggctct tccgtgtcca
    16861 ccagttccac aaggtcgagc agtttgtctt ctgccgcccg gaagagtcat gggacattca
    16921 cgagcagctc cttgcccacg cagaagagat atacacgctc cttgggctcc cctacagggt
    16981 cgtctcgatc tgcacggggg atatcgggac cgttgctgcc aagaaatacg atatcgaggt
    17041 ctggatgcca cgggaagaga agtaccgcga ggtcgtgtcc tgttccaact gcacctcgta
    17101 ccaggctgtc cgcctgcgta tccgcgtccg tgaccccagg aacttcgagt caaaacggta
    17161 cgtccacacg ctcaactcca cggccgtggc aacatcacgg acgatccggg caatcctcga
    17221 gaattaccag gaggccgacg ggcgggtggc agtcccgcgt gtcctgcagc cctacatgaa
    17281 cggtgcagaa tacctctgaa ccgctctttt ctcccctgtc cggatgattt cgttctcggt
    17341 cacgatcaca tccatgctca cgtccctgct atccgcaggg atctggtcca cttcctggca
    17401 tgaaaaccca atccctatct tgaacatgtg gggattgcgg gagaggaacc ggtcataata
    17461 ccccgcgccg tacccgaggc ggtgcccgtt ccggtcatag gcaatcaggg ggacgattgc
    17521 aacatggatg cttcccggat cggccggaaa ctcgtggcct atcggttccg gaacagaaaa
    17581 ggtgctgatc gagaggtgcg aagggtcacg gaggaaggag agtcgcaggg tacgctcttc
    17641 ccgctcgatg atgggcacga caaccgaggt cttccgtgag aagagggtcg taatcagcgg
    17701 tatcgtttcg acctcgggag gttttgagac atagacaagg acagggtcct gcccgtcgag
    17761 gagtgaaacg accctgttgc atatcgtgca gctgtattcc ttccgcttct cttcaggtat
    17821 cgccgcccgc gcttcccttg cccgtgtgcg gagcacctcc ttggagatgc acatgcttgt
    17881 ataattgtcg ttcccgacag gggattaaag gtatggtccc acaagtcggt ggggtaagaa
    17941 gacgggggcg ttcctgatgg ttttcgcgag gggatgatta tttgtttttc aaaaatattg
    18001 tttgtttttg taataaaaaa ataaaaaaat ttattactca ttctacccta cagatgaaca
    18061 ggtcgggaca gtcggggtga cgcccggctc ttttccacac tcaccatcag tgctgcacac
    18121 cctctccctt cttttttttc ttgtcccata ccagccggga tattttactc ccctgcccgt
    18181 tgcggggaga ggtcaaagct ttttccgaac atcataaagg ggctttttca cgggccggta
    18241 agggaaccgg aaatggatag cttccggcat cataaatttc ttatatatac ctgtcattta
    18301 tcctgaacac gatgcgcatc gcctggtata tccctgccat cgttgtcctg ctcttcatct
    18361 gcattattgc ataccctgcc tgtgctgccg gcgggggagg aggccacgca aaccccaacc
    18421 agtttggttt gggggagggt aagggaatcc agcacggaaa cggtgctgcc aataccggca
    18481 atgccatgca gggcgttcca gacccttcca tctccccgcc caaaaacagt caggggaaag
    18541 gaccggttct ctccgggaac agtgccggaa acccgtctgg cggtccttct cccctggtgg
    18601 gccgtctcac gggaaccgcg gccccatcct cctccccggg caatggtgca ggacccgttc
    18661 ggagtcctat gccccgcaac ccgcattccc ccggcccgtg gcattctgta cctgtccctg
    18721 ttcaggaccg gtatccctgc ggacctgccg agacgtcagg tcccctgccc gccggaggtc
    18781 ccgcagaacc ctctgcccac gtatctcccg gtatgccgcg ggtaaggcgc gaagagggtg
    18841 atgccgagga tgatggcggg agcccccctc tccccgggta cccggttcct gcgccctttt
    18901 taccggctct tggttaccgg aggataacaa gaaaaacggt ccttgccagt tctgtacgga
    18961 accgcgttta cactgcaatt gctgaaaatc ccggcctcga tgccccggcg cttgcagccc
    19021 tccttggcat gaatatcaat acgcttcgct accacctctt cacccttgca cgggaagaga
    19081 agattactta cttttcccgc cccggtaccg tccgctactt cgtaaacaac gggctcttcc
    19141 cgccccgcct ccagtgtctc ttccattacc tccggggtga atcgaccaga aaaatcatcc
    19201 tggccctggc cgaatcaccc gggatgacaa gggaggcgct tgcaacaacc ctcgggattg
    19261 cagggccttc cgtcacacgc cacatccaga acctctccca cgatggaatt gtggaggtga
    19321 ggaaacaggg gaggttttcc tgccattacc tgacaccgcc catacttgct catcccgcgg
    19381 ttatcgacgg ctgttccgtt caccagtacc cgtccaggga gtctgttctc gcctgcaata
    19441 gccatctccc tcgcggttca cccgcagaaa cgtagctgcc ggtgcgagag atcactaata
    19501 tcctcccgac aacgtggtat tcagaacggg tccacggtca acagacccgg gatcccgtcg
    19561 catacaggag gaaatcagaa atgaaaaaga tactgacact ctgcattctc ctgctcgtcc
    19621 ttgtccctgc gaccgtcatg gcagcaggag cacacgggca ggggaaaagt ggtgccggag
    19681 cacccgctct gggaataggg gaacagtcac tcgaatctgc acccgcatgc ggccagaacc
    19741 ggttctgcac aatgaacggc caggaaaacg ccgaccagta caggttcgcc gaaatgcaca
    19801 gggtatctgc aggcagggga atcggtgacc aggtgcgcat catggcaaga aaccagacag
    19861 gacttcagga tggaatcggt gaccaggtgc gcatcatggc aagaaaccag acaagactcc
    19921 gggatggatc gtgcgggaac tgccgggtcc agaccggata acccctttat gatgaaaatt
    19981 cccctcttct tttttcaaag actcttcatt taccctgcat ggactgcccc gcaacacaga
    20041 gggggctttg gatcattccc tgccaccggt tttccggctg ggactcgaga tatctgcaat
    20101 tctccggatt gtttccccct gtcgcccgaa tagaggcaca tttcaggata attcccggaa
    20161 ggggaatcca tttgtttgca aaaagagggc aatcacataa caaggatcaa agcgggatca
    20221 tgaaaagcct gatgtgaggg tatcgtccca tcttccccca tggaacttga ccgtatcagg
    20281 gagatgaacc gggacggaat tctctcgtac atcgaatttc ttctctggca ctatcgcgtg
    20341 gtggacgctt tctggttcat ttacgtaaca gaaaggtttg gccagcccgt tgccgagcag
    20401 atcaacgaac aggtctgggg gagggttgcc gggatggcgg cccgtgacct gaaagagcgt
    20461 ttttccctga agaaaaaggg tctgcgcggg ttttcagagg cactgcggct ctttccctgg
    20521 gccctcatcg tcgggtacct gatcgaggag ggggaggacg agatccttat ccgcgtcccc
    20581 cactgtccca cgcaggaggc cagactccgc aggggactcg acgagtatgc atgcagggag
    20641 atgcacaggg ctgagttttc cagtttcgct cgcgagatag acccacggat cagggtcgaa
    20701 tgcctctttg cgccacctga cccccacccg gaagacctct tctgcatgtg gcgtttcaca
    20761 gtcgctgacg agaacacccc tatccagaga tgaccgggac agggacctct tcatctttgg
    20821 tttttccggt aaattcctcc tgaaccttat tattccaaga gtcctacagg aaaccggtga
    20881 ggtttgatcc gggatacaca ataccttccc gcgtcacatg gtgcatgata tggtttccgc
    20941 ttgcccttgc gggtgcgatg gcccaggcga tgtactccgc aggagcaaaa atactcctgc
    21001 ggcaggtgcc agcggcacag gttgccgggg gatcttttct cgtcgctgct gtatcccttg
    21061 ccgccatttc cttctcaagg ggatttccat cgattgaacc gggtttttca gaggctgtgc
    21121 ttgtcaccgt tacgatcaat accgttgcaa ccgttctctt ctacagggcc ctctcgctct
    21181 ctgatctttc cctctgcctg cccatactct ctttcacacc tgttttcctg ctcttaacat
    21241 cgttttttat cctcggcgag atcccgagta ttgccggcct tgcaggtatc ttcctggttg
    21301 ccgcaggatc atacctgctt gctgctgatg gtacttctgg aaaggcacgg gggtggacgg
    21361 gaccattccg ttttctcctc tcggacaggg gggtccggtt catgctcgtc gtggcattcc
    21421 tgtacagtat ctcggtgaat tacgacaagg tcgtcgttga acggtccgac cccgtctttg
    21481 cttctgctgt cgtgctgggg ctcctcgcat gcatattcct cctccaggcc tcgatcccgg
    21541 tactatccgg aaagtcatat ccccctctgc ccagggaaaa gtccaggggg acaagtctgc
    21601 tcatgattgg actcggactt gtcctgacca tggaggcggt aacagtgaac actgcatata
    21661 ccctgtccct cgtcccttat gttattgcaa taaagagact ctcggtcctc ttcggtgtca
    21721 tcataggggg gtacctcttc agggagggta gcatccggca gagggccttt gggaccatcg
    21781 tgatggtcac ggggacggtt ctcatcgctg tgtggggtta ggaggggaga aacggcttgc
    21841 aggtggcgcc ttttattgcg ggattatggt acattattcc tttcggcaga gtagttcaca
    21901 ggtatatgac tgcgcaagga tgagtgaaaa gggatatact gaggcccttt atagtctgat
    21961 caagagatgt aaagaaatga agatatattc atgtcaaagg gctgacaccc gttcccgatt
    22021 caataaccaa aaaaccgcgg cggaaacgaa aggggttcat tttttattca aaaaaggcga
    22081 aatcgcctga atttacactc accatacccc cgaccagatt cgaactggtg tcgccggatc
    22141 caaagtcctg catgattgac cgctacacta cgggggtata cacctgattt cctctcgatt
    22201 gaacaaaaat ccatccggag ttttgttcca agaattattg tcatgcagaa tatttaattc
    22261 agggttattc ccctttcagc attgtcatct tctctcttcc gaaaaccacg gtcaatgcgc
    22321 gaaaaaagag ggttgtctct cacgccgctg atggcagggt ggagagaatc cgtgcaagga
    22381 caaaaagcag aatcccattg cagaagagaa tcgctgctgt caccatgccc gggatgagtc
    22441 ccggaaggag catggatgtg ccaaagagta tgctcacgat gttgaggact gtctgggtga
    22501 ggagcaggtt tctcaaaggg gtgggaatcg ggacgggggg cgccttcggg gttcccatct
    22561 gctgcaggag ggggaaaatc cggatggcca gaggaacgat cccaccggcg atgttcagta
    22621 ttccgagcat gatccggagc acatcggtca tgatacccgg gacaatgcag gaaaagactc
    22681 ccagtgcaac gaaggcaaga ccgatcgtga caagcgtcca cgagcgccgg aaccggccga
    22741 ctggtgtctc ccccactgca agcacctgga tcgccatgat aacgagcagg agaccgaact
    22801 ggccatcggg agagaagggg agcgttccca tggtgattgg cacgagcagg actgccagga
    22861 acgcaaggag cacaccgagg aagacaagga gagctgtcgt gaaggtgaga ggtgcctccc
    22921 ggaggaggaa gaagtgtcgt tcttcggacg gtcccgtgga tggtggcagg gaactttcgg
    22981 ggtattcctt cctgacgacc tggatacacc atgcaaggta gaggaggctt ataccataaa
    23041 cgatgaggaa gactgcggtc agccagtcgg tcgtgagagc aggcaggatc gtgacgaggc
    23101 cgagaataaa agccatgagg tacacgagga agcaggcaag cgtgaggtgc cggaggatgc
    23161 cgggaacctt cagccacgct ggagccctgt ccctgcggga agcaagctga aaaaggagga
    23221 ccgcacctcc ggacaagagc agcacgccga caaggatcct gacaagggcc gagagggatt
    23281 ccgggataaa acaggcaccc ataccgatga ccgaggccga gatccccacg atggtgacaa
    23341 gccaggatcg gcgaacgtcg ccaaacgggg tcctgcccat ggtgatgacc tgcagggaaa
    23401 cgataacgag aaagagtccg taggtgctgt ccggtgcata gggcagatcg ccggtgtgga
    23461 tgaaaaagag gaggacacca aagaggagca tgaagaccga gagcacaagc aggatgacag
    23521 cctcgagtgc aatatcgagt tcctggcgct ttgatggaac tttttgatga aaatcttcca
    23581 cgattttcct ccaaaaatta ttttccggat attgaccgta aaaccacata gtatttttcg
    23641 ggggagacct ggaaaatgaa aggtatgacg aacctgtatt atgcatgatt tttatagtct
    23701 ctgcagcaat ccagatatga aaacatgagg aatgtatcca tggtgtcctt ctctttacgc
    23761 tcgattcctg ctgttatcct gcttgccatc gccctggtgg catgcacggg acaggtctct
    23821 gccatgatcg gtggcggcac gggatatttc cagatctcgt cttccccgtc gggtgcaacg
    23881 gtctactttg acgggacata ccggggcgag acccctgtca caattcctgt ttccacaaca
    23941 ggaaccccgt cccattcgat ccggatcacc aagaccggct acactgaatg gaccgatacg
    24001 tatgagggca atcccttcga gggtgagacg atccacatca gcgcgacgct ccaacccctg
    24061 ccgggtgggg gtaaaggata ttacaggata tcctccagcc cttcgggagc atcagtctac
    24121 ttcgatgatt catacaaggg gaccaccccg ctcaccataa ccgtttcgac aacggggacg
    24181 ccggggcata ccatccggct cgtgctctcc ggctaccagg agtggagcag ttaccagccc
    24241 ggcaaccccg gcgaggacga gaccgtttac gtgacggcaa cattgcagcc tgtccagact
    24301 tacgggagca tcaccgtgac gtcatcaccc tctggtgcga ctgctgttct cgacggcgcg
    24361 cagtcaaagg tcacaccctg cacgttcgat aacgtgcttc ccggtctcca tacggtccag
    24421 gtgagcaagt ccgggtacca ggtatggagt acgacaacat cagtcagttc cggcctgaat
    24481 acacaggtct ttgcatcact ttccccaatc actcctgcga ccggttccat ctatgtcacg
    24541 tctgtcccct ctggtgcaag tgtctacgtt gacgggacat actatggccc ttcgccgcag
    24601 cttgcatccg gactcccccc ggggtaccac caggtcagga tatccctctc gggcttccag
    24661 gactggatag ggaacgtgtt ggtcaactcc ggtgagacga cgagggtctc ccagacactc
    24721 tctgtcaccc ccactccaac ccaggtctct ggtacgggtt cgctgtccgt ccagtcgaat
    24781 cccgccgggg cgagcgtata cctggacaac gagtacatgg gaattactcc gctcgtcatc
    24841 ccttcggttc cccctggtat gcacaccgtc ctcctgaccc atcccggcta taccgactgg
    24901 agggcaacta ttcaggtcaa cagggacacc cagacgcccg tagatgcaac actttcaccc
    24961 tccccgacca taaccccgac gaaggccccg ctcccggcag ttcttgccct gctcggcatg
    25021 gggatccccg tgttggtagt atggggaagg agacggtgaa aagatccttt ttcctttttt
    25081 tcgcatcaga aaaaatcaat catcgtcggt tcctctccct ctttcccacg gaaagtggcc
    25141 accggcaaaa aaaacgtggt ctgtgatacc atgaattggt atgcagaact ttaaagcaga
    25201 aaaaaaacat ggaggggtct cctgtcgctg ctgataatcc tccggttacc ttttaaaaaa
    25261 aaagatagaa tattccctac actaccggga actgctcggg gttgatgggt atcagtgccg
    25321 ggtcccacca ggacgatggc gggtaccact gaatgaaggt cagggtgagt ccgctgttcc
    25381 cggaccctgc aaagacctgg ggtgctttcc acatcaggta gcctgtctcg actgcgaatg
    25441 ccttttcttt cgggttccag cgttccccgg ttgttatata gacatcgtat atcccgggcg
    25501 gaacgacctg gtcaaaccgg tgtgaatgcc cctttgcaac gtataccgcg aggatagccc
    25561 cccgctgacc cctcggggtc agggcaacca caacgtcgga cgtacctttt gtgttatcaa
    25621 ctgcaaggaa ttgtccaccc gggagcagtg tccccttgag caacgcctca cccggaatgg
    25681 tcacgtaacg gttcctgact gcagtatcga ggaaatgttc gataactcct ttgagagagg
    25741 ggttacggtc gattgccatc tcgtagtctg caatcgcgtc gtcgtagcgg cccagctccg
    25801 cgtatgcctt gccgcggttg aagtatgccc tggcaaagcc cggatcgagt tcaattgcat
    25861 gggaataagc gtctattgca agatcccatc gtaactggct ggaatacgta ttcccccgat
    25921 cgttccacag ggaagcagtc attacgggta tcgactcatc cggtcccgga gaatcccctg
    25981 ctgcgacggg cagggagata agagggatga gaatgaggag gatgaaaaaa tgaaaagtca
    26041 ttctctggtc tgtggcagtc attgtggcat ctccattaca ggaatatgca gggtgtcata
    26101 aatacatact cctctgccct catgcgccag agtaacatac cgctggacat gccccgctat
    26161 atctcccttg cacccatagc ttctgcaaat gtatgtgatg tgccatctcc tctcgggcat
    26221 cgttcctggt actctcctct catattctgc cggggacagg cggatggcta tcgcctgcac
    26281 ggtgggcgca atcctccctg acctcgtgga caagccactc ggacttgtaa tctcgggtac
    26341 tgtgggttac ggaaggattt actcgcatac actcgtgatg gggctgttat ttttcggcct
    26401 tgggattgtt tcgtgggcct tcctccgaaa atacgcctgg aacaccgggg tactcgttgc
    26461 actgggcatg ggatttctcc tccaccagat cctcgacgcg atgtggcaga cgcctgcaac
    26521 atggttctgg ccattcctgg gacctttccc tccgggagag agaattgcga ttatcccgta
    26581 tatcctcgct gatattcttc agcctgcaga atggctcgca ggaatcgcct tcatctttct
    26641 ttttgcctgg ctcatcggag ccggacgtgc acgggcgcca tatggggcag gattgtcact
    26701 cgtccttggt ttttctgctt tgtggttgac gatttgtgca ttgggtggat cgttctgtcc
    26761 gcttacaggc tgggattccc ggtccgataa cctgattgtt gcactcgtcc ttcttggggg
    26821 agcgatctgc ctggcaatgg aaaatgcagg gttcatgcag ggagaaggga aggattcaaa
    26881 aaggctgcaa tgagatgggt cctgtccctt catccagcag accagtgaag tgtgattcaa
    26941 cggattcaat aatattgctc ccggatggag cctaccctta tttaattccg gatttacata
    27001 ccctgtgcaa gacatgttca cctttgtcct cggcacgcgt cccgagatta tcaagtgcag
    27061 tcctctcatc cgcctcttcg agagagaaca tgtgccttac tccatcatcc acaccggcca
    27121 gcactattca tacgagatgg accggatctt tttcgaggac ctgcagctcc cggaacctga
    27181 atactccctg gatgcgggat cagggtccca tggcaggcag acgggcacga tccttgaagg
    27241 ggttgaaaga atcctcatcg cccacactcc atccgcggtc cttgtgcagg gagatacaaa
    27301 cacggtcctt gccggggcac tggcagcagt aaaactccat gtcccggttg cccacatcga
    27361 ggccgggtta cggtcctttg atcggagaat gcccgaagag ataaaccgcg tcgtaaccga
    27421 ccacatttcg acgtacctct ttgcacccac gacactggca gaaaggaacc tcctctccga
    27481 gggtattgat ccggggacga tccacgtttc cggaaatacc atcgtggatg ccgtgttcca
    27541 gaaccttgac atttcgagga agaaatcagg ccgggtaacc ggtaccggcg gattaaaaga
    27601 gggtcagttc atccttgcaa ccgcacacag ggcagaaaat gtggatgtca aggagaacct
    27661 gaaaggaata ctggaaggct taaagagcct tggcaatgag acagggatgc ctgttgtttt
    27721 tccggttcac cccaggacgc ggaagatgat ggaaatgttt gccctcgaaa gtgatggtct
    27781 tttcaccatt cctccagttg gatacctcga atttctccgt ctcgaggctt cttcatgcct
    27841 tgtcctgacc gattccggag gagtccagga agaggcctgc attctgaagg taccctgcgt
    27901 caccctcagg gagaacacag agaggcctga aaccatagat gcaggggcta acgtgcttgc
    27961 agggaccgat ccgttacgaa tcgtcaggga gggccttgca atgatcggaa agaaaaggga
    28021 ctggaaaaac cccttcgggg acgggcatgc tgcagacagg atccttgaag tactcctgga
    28081 aaggctctga acggggaata gagaccggga aagtttttct ttggagggaa tccagaatcc
    28141 tttatgaaaa tacatgttca aaggaaaatg catggacgga ggtctctggc tgttcttctc
    28201 ttcctctttc ttctcatcat cccggtcgca ccggtgacca ttaccgggcg gcccgagact
    28261 gtctcaaatg gtcatccact ctttgtgacg atcacaagtc ttccggacgg ggcgcaattc
    28321 tcactcctcg tggaagcaac gtacgatgta tctcccaata ccgacttcca gttccagatg
    28381 agccagttta aaatgccttt ctccttaaag aaggggagta tcactgcgac actggagggg
    28441 acgtcgcaga accgcctcga ggtgaagaaa gaggacacta tcgtgagtgt gtccggcaag
    28501 tcaacagatg gccggttcac taccacgaag tcctacgata ttacggcagg aacctatgac
    28561 tatttccggc tctcagggac cacgctcccg tcagcgcgat cgattaccac ccggttccag
    28621 gtgacgggag tcaagcaggg ccctgtggat tccgagatcg ggttcgtggt cgacggtctg
    28681 ccctcaggca cgataaccct ggccgccctg gtggatggaa cccaggtcct ctacaagact
    28741 attcctgtcg gttcaggaga gccgccccgg ttaataagcc agccatccac caccaccgga
    28801 ccgtcagtat cccaggaaac ggtctctttc acgtctatcg atgagacagt gaaagtcagg
    28861 gtgcctccag gcgtgcagat cagcgtcgtt ggggttccat tgccagctgc accggaggag
    28921 atgcaggtca ttgccgggcc ctatgccatt gtaccttacg aagcagtctt ttctccacca
    28981 ggagagattt tgttttccac cggtaacact ggggctggta ataataccgc tgtagccttt
    29041 ttttcaggtg atagctggac actcctgcca tcaatggctg caggaaacca cgtagctgca
    29101 cctctcggca agggagggat gtatgccctg gtccggccgg ccggcaccgt ccatacacag
    29161 actattacaa caaagactac catgcctgcc acgatgacca cggtcccggc gactcaaatg
    29221 actgcggcag cgtctcccac ccagaaggcc ggcctctccc ccgcaccagc cttgactgca
    29281 gtcgtgatag ccatgatagt atttggaata gcgaaaagga agtgacccga aagtgttccc
    29341 gggtcatgcg ccggatggac gccccccctt ttttaacagt tcccaaaggc cctttttaaa
    29401 accccccatc aggcagaggt tgaatagatc ccggaaccca cgaaccattc cgtgtctacg
    29461 ggaacgacgt aacagagctt gagagcttcg ttcccggtcc cggggttcgg gtataccacg
    29521 tacacgaaac cgccacctcg tgctgcaacg tcacattccc attcaacggc cgcaacaccg
    29581 taatggtcca aaaatccaag cctgtttgtt cccattaatc cgggctggtt cgggagagca
    29641 agggttgtac cgttcagact gtatgcaaag atatacgatg caccatctgc ccacggtccg
    29701 gaaaggtcgt tgaaggccgc aagggctgcc tcctttccct gctgctgcgc aaaatcccgg
    29761 gcctttttca ccctctgcac gagctgatcc cgttccttct ggctgaaacc ggcatcgaca
    29821 tggggcaggt atactccgga accgacgaac cattcatcgt ccacggggac aacagaggat
    29881 aatttcaatt gcccggaaaa acccgcggaa ggattgggat acacgtaata agtgtgccct
    29941 cctccacggg acgcgagggc aaccatggca cggatatatt caaccccgtt gctgtcccgg
    30001 acatcgatac ggttttcccc gacaagtccc tgctgatagg gaagggcaag gaccgtcccg
    30061 ttcatatcgt atgcgaatat gtaccattca cccttggaaa aacgtccctt ctggtcattg
    30121 aattcccgaa gagcttcgtc tttgcctgcc tcccgggcaa acgaggcggc gtcccggaca
    30181 aaggaatcga gatttgacag gttctggaat gatgcattgg gcaataaccc tgcaccggct
    30241 ggtgacgctt cgtcccccgg ggatgtcagg acaacacgcc attccgcccc gtcaattcct
    30301 gccgttgccc atactgcttc cttggtgatg acacggtccc agttccggtc ccagaaacgg
    30361 taaacacccc tgccttccgg ctcggatacc acgcgagaga agaatgcctg aagttccggg
    30421 gactggtatg caggatcgga gaagaggttt ttcccgatct cctcctgcgt tgtatcataa
    30481 attacccttc cgtctttctg gaccacccag atatcatagg ccgtcgctgc aatgaccggt
    30541 tccaccgccc tcccgatcag tgtctccggc cgataggtta cgtcggtata tcccatgtaa
    30601 atccctccgg gagaaaaaac gggggcactc tgtgagatcc cggcaaagcc ttcctccatc
    30661 atgaatactt cactcacccg cggagccttt ttttcaagcg catccctgac tgcgtcctgg
    30721 taattgacat ttctgcccac gatatcccgg aatgttgccg ggacagccgt ggcaattatc
    30781 ccgtcagatg agatggtgac cgaagagata gcccatggca gggcaacgag tttctctgac
    30841 aggaccgctt cgacttcccc tcctctcaga ccaaccgggg agaggcgttc tgcactggcg
    30901 agatttactg tgcggacaga ggcgagttct gcgttgatgg caccgacggc ctgacccaag
    30961 gttatgttca tggggttttt cggggattcc acgacatccc ttgtcgtgat gcaaccctgc
    31021 gtaacaagca ccagtaaaac gaggatgacg gcaatgcggg cattcatgtt ctgacctttg
    31081 gcgccggagt atgcataatg gttgtggaac ccccggaatt cccgggatga cgtgtcattc
    31141 cattgacaca agggtatcag aaaggccctc ttcgaggctg aatgcaggtt cccaaccgag
    31201 gagtgagcga gcccgcgaaa tatcagcgac agaatgcatg acgtcccccg gtctcccccc
    31261 ggcatagacg ggctgacccc tgaaccggag gaggcgcatg aggatggttg cgagttcgtt
    31321 gatactcgtc tccttgccgg atccaatgtt atagaccccc tctgcatcac gttccattgc
    31381 caggatattt gcccttacaa cgtccctgac gtacacgaag tcacgggtct gggttccgtc
    31441 tccgaagatg acagggggtt ttccgttacg gagattcgcg atgaaacggg ggatgacagc
    31501 ggcgtaatcc gatgccgggt cctgtcttgc cccgtacaca ttgaagtacc ggagagagac
    31561 cgtggggaga tcatagagaa gtcccaggac cctgcagtac tgctcacctg catactttgc
    31621 aacggcatag ggagagaggg gttcaaccgg catgtcctcc ctcttgggaa tcccgggcag
    31681 gtttccatat actgctgcag acgatgcgtg cacaaccttt ttgacacccg tatcccgtgc
    31741 agccaggagg acattgaggg tgccggtaag tgttacttcg tggctttgca gcgggtgtct
    31801 gatggaacca ggtaccgaaa caaacgccgc ctggtgaaag acgccatctg ccccctgaaa
    31861 ctcttccagg aggagaccaa gatcgagaac cgtcccctga acgaacctga ccctcgggtt
    31921 ggcagagacg cttgctatat tctcgatcct gcctgacgag aggtcgtcga tgacaaccag
    31981 ttcatggcct gcaagggaaa gtgcctcgac aaggtgcgac ccaatgaaac ccgctccacc
    32041 ggtaacaaca tacagcatgg ttcttcagct gcctaatgtc tctcgtcaag agaccttaaa
    32101 ttgcgtgcag gtatcgctcc aggtattcca ctccgggagt tttgcttcgg gccggaaatg
    32161 aaacctctcc cgggatgaaa caccgccctg aaaggttaaa tgtttttcat gctgaagatc
    32221 gccccatggt cactctcacc gacattcagg ccgctgcagg actcctcgag ggaaaggtga
    32281 tacggacacc cctcgtccac tcgccgacct tttcggcaat aacgggtgcc gaggtttacc
    32341 taaaactcga atgtatgcag aaggctggat ccttcaaggt caggggcgca acatgccgta
    32401 tccttttgca gagggatgag atcggcccgg ggggagtaat cgccgcctct gcaggcaacc
    32461 acgcccaggg agtcgctgtc gcagcttcca tggcaggagt cccggcaacc attgtcatgc
    32521 ccacgtgggt ttcgcttgca aagcaggaag cgacgatagg gtacggggca agggttatcc
    32581 ttgcaggaga gagtctcgaa gagagtatcg ggtttgccca acagttcgca atggaacagg
    32641 gtctctcctt tatccacccg tacgacgatc cgatggtcat tgccgggcag ggcacgattg
    32701 gtcttgagat cctttccgat ctccctgacg ttgagtgcgt ggttgtgccc atcgggggtg
    32761 gcggactgat cgcgggtatc gcaaccgctc tgactgcatc gcagcgaaaa attcgcgttc
    32821 tgggtgtgca ggcagaggcc tgcccgtctg caagagaggc actcagggcc gggcaccctg
    32881 ttaccgtcga agcccgtcca acaattgccg acggaatccg ggtcaagagg acaggggaac
    32941 tttccttccc ggtcatccgg aaacttgttg atgaggtcgt tctcgttgac gaggaggcca
    33001 tcgtaaacgc ggtcctcgcg ctcctcgagc ggaagaaggt cctcgccgag ggtgcaggtg
    33061 ccgctcccct tgcagccctc ctttccggcg gcatcagggt gagccggggc gagaaggtcg
    33121 ctgtcgttat cagcggtgga aacatggacg cttttctcct ggaaagggtt cttaagaagg
    33181 ggctatacac agggggacga atggtccaga ttcgtgtcgt gctcgaggag gggaggggct
    33241 cgcttcctgc gcttctcgat attatcgcca aacagggtgc cgtggtcagc cagatcttcc
    33301 aggagaggag tgtccccggt ttgcccgtgc accagatgag ggtgacgctc gaactggaag
    33361 tgagggacct tcctcatcgg aaagggttga ttgccgccat gagatctgcc gggtaccctg
    33421 ttgaagcctt cccggaggat tagagagatc gacctggaga gaacctacgt ggacagacgc
    33481 caccttgtgg gcatcgtggg gaggtgcccg gaaggagagg gttccggtca cgagatcgag
    33541 ccggtccacg agcccgagtg caatgaccat catttccgga tcacacaggg caataaggag
    33601 atcgcgccat tcgtcctcgc aaaatgactc tggtatcctg ccgtgaatgc caaggcccga
    33661 caggaacctg gcatgcggca cagcacctga aaagtactct gaaaagcgct ggaaccgata
    33721 gagccgccgc cattctcgct ttctttccac gacctccgcg ggtgttgcac actcgaatat
    33781 gctgatgcgc gggtggcggc ggaagttaac gaggatccct tcgagctctg gtcctttttc
    33841 gaacccgacg atgacatccg gctggagcag gtctatcatc ctgacatgaa actcctgtgc
    33901 ggcaggctca acgacccatc ccggtgaatc tgccacgagg tacagagctc cttcctcttt
    33961 cgctttttct ttcagacgga gcgctcccac gagctcctgg accatgtgac cgctcggggt
    34021 tacggccccg acaaacctga aatatgttgc tttcgggaca tccacagtac ctgaatagag
    34081 agccagtccg actgtggcag gggggccgag agtggactgc ccgatatcgc agtcgagaaa
    34141 tcccgtcatg ctgatttttg ccagcttgga ggtcagccag cggcaaaagg tggtctttcc
    34201 cctgtctgcc gcgccgacca catagaccat ccccctcctg cgctctccaa gaaaacggag
    34261 tatctctttc cattcctccg ggacggtgat ttcctgttcc acgtggcttt ctccttgtgc
    34321 acgttattct ggctgacccc cgaacagaaa atgcctgcac agagcagcgt gctctatgga
    34381 gtctattctc gttcattcca taagagagta gcgagggaga ggggatccag agaagaataa
    34441 ggagtatttc cagtggaaat aatcaagcat tttgagagtg atatataaat ttatattcgt
    34501 tattttaaca aaatagctca ttatatcctt caaaatgatc acgcattatt catggataca
    34561 attctatttt gtcttccgga tttttttctt gggagatgga aaccgggatt tgaatgcggt
    34621 ctacagtcgg aaaagcaata cgagttacaa tatagcatta tatagtttat attaaattat
    34681 ggtggctgca gaaatttaaa agaatggaac tcaaaacatg agaaaagaga gccattacgg
    34741 aaaagatacg gcaatataaa aaaatttccg gggaaacaga aaaccgaccc tgaacatctt
    34801 ccgaaatatc cctaacaagg acactcaaaa cggatcatgt ctgttatttc aataccgttt
    34861 tcagaggagt gaaaaataat cgtctcgcag ggcaccatct tttccattca tcgtgttcag
    34921 acacgaaaca tcctgccgaa gcacacttaa gggacaccgg aactatccgc tttgggggtg
    34981 cgggacctgc caaccgccgc cttattgccc caccttccct taaaagggga ataaccccat
    35041 tgacttcagg tatatccctc acgatgcgtc atggtccgcc tcattttccc tggcctttgt
    35101 gctcttctca gcaagtggga aaaattcctg gtaaactctt tttctctcct ccaaatcggt
    35161 atgaaggtat atttcggttg ttttgattga tgtgtggcca agattttcct ggacgacacg
    35221 cagattcttg gaccgcctgt acagctcgct tgcataacta tgccggatct tatggggagt
    35281 gattccctcg ggggcatact tccggaaaat gtgctggaca gcccggggag agatgtggtg
    35341 acccatctgc ccaaggaaga ggggcccctc gattcgtgag ccaatgaacc tgtccatctc
    35401 ggacagcgtg tcgggatcca cgaaaactat ccttatcttc ccacctttgc cccgcacgcg
    35461 gattgtcccc tcttcgaaat cgatatcctc gatattcatg ccgcacagct ccgacaccct
    35521 tacaccggtc gcgtagatcg tcctgacgat cagacgatcc cttggatcct cgatggagtc
    35581 tatgagccgg ataacctggc tgtgcttcag gtaacggagt tcctgcccct tgatctttgg
    35641 cctttccaca cctatcaggg ggtttgtcgt cactgcaccc tgggaataga gaaagcggta
    35701 aaaggaactg agcgttgata tgacccggtg catggtcttt ggcttgtatg tccgcatgga
    35761 actgaggaaa gagaggtagt cctcgaaaag agccggttca acctcgacat ccgtttctgc
    35821 ccgcgcttta ctgaagtctt cccagtacac catcagtttc tgggggtcga tatttcgccg
    35881 gagccacacg taataggcaa agtgcctcac aacctgctca taactctgga ttgtccgcgg
    35941 ggaatagtta cgcattctca ggtagtgacg atagcgtccg agccactctg agaaaaatcc
    36001 ccctggcatg ttctattctt tttttgctcg aattataaac cttttgcgca gaatctctct
    36061 tctgcgaaac aggaagatgc actgataaca atccaacaca ggccgtatcc gggatgactc
    36121 tgaccctcca aaaaaacaat tagatcaaga aaacctgcat tcatcacctt cgtgagacca
    36181 gtgtgaaggc ccttcagccg atgcatggtc ctaaaataaa tccatttagg aatgttccta
    36241 tcctgcgtag aaagtgaatc ctgaattaaa atttggatgc atccgcgaga tcctttcaat
    36301 accaggtttt cgcttcttcc gacatactaa aacgaccaga aaaaaactga aaaataaagc
    36361 ccattatttt gataaaatcg gctttttctc cttgaaccaa ggagaaatat cttatgaata
    36421 aaaataccgc gctgaaatcg ctctaatatc gtgctaatag atcaacgcgg aaaggcagtg
    36481 ttaggaagat ggtagtaacc ccattccaaa aaaataaatg gagatattaa cattagcccc
    36541 ctcttttttg catacgacga tttcgaaaaa cgtatgatcc acaaagaagg gatagccagc
    36601 attcacactt gaaggctcga aacgaagatt ttcactctca catttcccaa atcgcttgat
    36661 ttttgcttaa tatgtaaggt tttttagata gctaccgcta ccaggctcct ttccgtttga
    36721 gtgttcctaa ttggaccaga ttgaatgaaa acgctgaaaa catgttcttg agatggactc
    36781 tcccgagagt tgtgaccagg acatgacctc catggaacat tcgtttgatc acggcgaatg
    36841 aacgttcaat cacccttctc actctgctga ttgcgcggtt cctgcggttc tccctgatag
    36901 tcagtggacg cccccggact gcccggttca tcgttttgtt gatcgatgca cggggtttta
    36961 caccgaaata ccctttatca cgatacacag tctcaccagg caatgagaga tccacctggt
    37021 tgtcatggac agaagcagaa gttgtctcaa cacggcggat caggtggtat tctttgtcaa
    37081 cgagtgcatg gaacttgtat ccaaaggagg gagtctctcc tcgttttgtc cacgtaccgt
    37141 ccctgcttct ccgcgttttt ccgtctttcc cgcgtgatgt gtctgatgaa cgtgctcccg
    37201 gatcagcggt aatgatggtt gcgtcctgaa tgactcctcg tgttatcttg aggcctttga
    37261 gctccaactg cgcctggaat gtgttccaga cttcctcgta tttccctgat tgtatgagac
    37321 gttcgcgaaa gaaccagact gtcgaaaaat cgggtatttc agtcgtgaat cctatgaatt
    37381 tccggaaaga tatccgatct gtcacttggc gttcaagttc cgggtcggag agattgtaga
    37441 gggactgaag tactaatagt ttaatcatca caacagggtc gacattcggc ctgcctcctt
    37501 tgcgggtgtt gttgtggtag atatccgcaa ataaaggacg aaattgatcc cattcgatca
    37561 aggattcaaa ttcagataaa cggtctccta ccttttgtac ccttttatac gcctcattta
    37621 atccaaacgt ctcaaaggtc attgagaata ctccgatcag ctaagataaa gcttttgtgg
    37681 tttgagggag tatttcgaaa ttctcgtaaa gcattgctac aatagggaaa tacctgaaaa
    37741 aaaaaagaca gggaaaacac ggcggaatga atctcgggta ttgcatagag gaattctcct
    37801 ggagcctgtt ttatgtcaac cagatttatc gaatctgatc ctctgtctaa tcatcatact
    37861 gaatgacaac ctggcgaaac cacgaaaaac cttccagaga tccagaactt gcatgtctcc
    37921 atgccatcat tatattttct cttgaagaat atccggatat tcctgctggg gacccggtcc
    37981 tccccaatcc gtaaagaaca tggaattacc tcgatttgct ccctccggtt tgaattggtc
    38041 tttcttttca tctggctgac tttcgggtta acattcaatt cgtagagatt atttccggct
    38101 tttcacttcc cgtatactat gtcgggagat atattgggtt gaccggggca ttcagcgaag
    38161 tgaataaaag gaatgttagg gtcaagacga aaaagaattc acccgaaaaa gttccccctg
    38221 gccttgtaaa acgccataag gagaccattg atacgatttt agggcgcgag ggaaaaacag
    38281 tccggcgatg aattataaac catataatgc tacatattca ttatacgtga tatgaccggg
    38341 aatctgcagt ataaagaagg taacggtatg ctactggtat atcgttccgc ccgaaggtgc
    38401 atgatgtttt ggtcaatgag gattcccata cagttaagag gatgctgcct gtctgaatta
    38461 tttggaactg ggatttccat tccctatagg tttaaaaggg atatcctcga agtacccttt
    38521 atggcagtcg cgatgacttt ttacgcttgg ttgcctggaa ggcattcttc cccatgataa
    38581 cggtcctgtt cgtggatgac gagccagccc tcctggacgt ctcgaaactc tacctcgaaa
    38641 agggtggaga gataaaggtc gatacctgct actctgcgga gcaggccttg gaatatcttc
    38701 gaacccaaac ttacgatgtt atcgtttctg actacgagat gccggggatg aatggtatca
    38761 ctctcctgaa aactgttcga aatcttggga tagaaacccc cttcattatt tttacaggca
    38821 gaggaaggga acagattgtc atagaagcgc tcaacagcgg tgcagatttt tatctccaga
    38881 agggaggtga tccccgttcg cagtttgcag aactcatcca caagatacga ctcgcagtcg
    38941 agaggttccg ccgggaaggg gctctggagg tcacgcgata ctctgtcgag aaggcaggtg
    39001 tcccgatatt ctggttcgat agtcgcggtc gcgtgttgta tgcaaacgaa tcaggatgtg
    39061 cacttcttgg atattccatc caggaactct gcctcctccg catcggtgac atcgatccct
    39121 tcctttcact tcccgaatgg acacaattcg tcgaacggct caagtcacac gaaagaatga
    39181 cactccacct catcatgatg acgaaggggg gacaaaaact gccgctgccg gtctccttct
    39241 cctgcggtga attcggggga aaaaccatta tctttgccta ttcatatcca cgaacaggaa
    39301 aagaggaaaa tgaggactgg aagaaaggac tgagttctta ccggcatatg cttgccgatg
    39361 caatacccgg gatttacatg gaggtttcgc cttccggtga aatttttttc cagaacagta
    39421 ctgcaagggt ttttttcggt ccttgcgatc ccgttgaaag caggaagcgt tgcacccttt
    39481 ttgacctaac cgtgaagggg cagcacaggt cacttgcaga ggtcctttcc cgtatccgcc
    39541 tggcaggtga agaagaactc gttgagctct ccctcgtccg ccatgatgga acaccctgca
    39601 cgcttctttt caagacgggg gtgtgccctg gtccccgagg aatcgatgga acttacttta
    39661 ttgaatccgt ccctccctga ttcctcagga gacttcgtac tttccttaaa acctgaaatc
    39721 tggctcttaa actttttatt tgatgaaata tcgggaaaat gtgattaaat cagtatcaat
    39781 cgatgtcatt aaataaacca tataatgcta tatataagca ggatgaacat ttactgaccc
    39841 ccgacaggaa atgggggggc tacgggaggt aagacccgga aatgcgaaca catttcggac
    39901 aggatgacgt gaacaagtac cgcaagttca agaaagtgga tggggccaca tataataagg
    39961 tgaaccagtt cctgcggaaa cggacataca tcactgccag ggaatgggca attgcccgtc
    40021 tctgcaccga tttccgcacc cggagcggcg cagagatgac cttcatcggg cagaaccttc
    40081 ccaggctcgt acctttcatg caggagccct attctcccca ggccgtgaac caggcccgca
    40141 actcatttaa aaagaaggtt tacaaggctg gtgcaacgtt cttctatggg gcgatgtgcg
    40201 gcttttttac aagcgaggaa cttgatgatc tcctgttcga ggcaagcgaa gttgcccggt
    40261 tcctccttga agttgagagg acttccctgg agatagacga ggaaattgag atagaagacc
    40321 gcattacgga ggtcatgagg agtgtcggga aagcggcagc ccacatactc aatacgcgta
    40381 tgcaggagga tgagacaggt ttaccaacgg gagaaggagg agagagtccc ctcacacggg
    40441 ataccagcga taaaagggat gcggagccac cccgtcaacc ggagaacgtc gacagggagg
    40501 aggaaacaaa accgctgcag gaaggatacg gcaaagagga ggaccctgca tgaaagttat
    40561 ccatgtctgc gggacgtcgg gttcgggaaa aacaaccctc atccgcagcc tcattccact
    40621 cctcgcagac aaaggggtcg tagctgtaat caaacacctc ggacaccatg tgtttgcact
    40681 tccggaaggg aaagatacca ctctctatct cgaatcgggc gcaaaaattt ctgcaggaat
    40741 tgatcccgaa aaaacggttc ttgtcactga tactgtctct ctccggaccg ttctcgacat
    40801 gctctccttt tccggcacgt cgtttacaat cgtggaaggt ttcaaatcgc tcccgatgcc
    40861 caaggtcgtg gtgggatcat taaatgatgc ccataacgtt gtcctcgaaa atccccgtcc
    40921 acgggatata ctcgattctc tcgggaggtt cccggactat gtctcttact acgaactcac
    40981 aagagatata tgggctgacg ggctcattgc ggtgagtggt tctcttcccg ttgattcttc
    41041 tttgctacac ccccgcgaga gaagagagtt ttatgaccgt tttttcccaa tgatacatga
    41101 tatgacggga aagggagcag gcgtgtcgga cgcctccagg gtgagggtcc acctttacca
    41161 ggggctcttt tttggagggg aagacagggt gatctatgct gttgggagcc cgacagtgga
    41221 agctgtcaat tctgcggttc cacgaatcct tgaacgcata gaatatatgc ttaaacttgc
    41281 gttgcatacc ggaaggagag attcatgcac ctgaaaaaaa ttgaaaagag gctctttgga
    41341 accaacggcg tgaggggaat tgccgggaca gaaatgactc ccggattagc actcaaaatc
    41401 gggcttgcac tgggaacaat gcggcagggg actattgccg ttggcaggga tacccggact
    41461 tccgggccgg cgctggtcag tgccctgaaa gcaggtctcc ttgcggcagg gtgtgacgtg
    41521 gtcgactgtg gcatccttcc gaccccggca ctccagttcc ttgtcaggag gcactttgat
    41581 gcgggagccg tcgtgactgc atcccacaac ccgccggaat acaacgggat caaggtggtg
    41641 gaacctgatg ggacagaaat gggcgatgaa gagagcgtcg ctctggaaaa gcatatattc
    41701 gaggatactt cacggattgt ctcctgggaa agaaccggac gcgaacgctc tgcccctgcc
    41761 ctcgtggaag agtatgttga tgccgttgtc cgcgctttcc ccccctgcat tggcgaaggg
    41821 atgccggttg tcgcagaccc gggatgcggt gcagctgctg ccacaacacc ggaaatcctc
    41881 aaccgcctgg gttgcagggt ctattccctc aactgtcaga tggacgggac attccccgcg
    41941 aggcctcctg aaccttcggc tcagggtctc ttgccccttg ccgatctcgt gaaaacgacc
    42001 ggtgcatcct ttggcgttgc ccatgacggt gatgcagacc gtgctgtctt cgtggacgaa
    42061 aaaggtcatt ttatcgagga gaacgtggaa ttcggtctta ttgctgatca tgtgtgccaa
    42121 gggaggaaag gagtcattgt gactcccgtc agcacatccc ggatcataga agttatcgga
    42181 aaaagaaacg ggtgtcgggt tgtctacacg cccgtcggga gcatttacgt ggcaaggaca
    42241 atgatttccc tcgctgcaca gggaatcccg gttgtattcg ggggagaggg aaacggggga
    42301 ctgatttttc ccggtcacca gctctgcagg gacggcggga tgactgcagc gaccatggtc
    42361 tcgctccttg cccataaggg agagtccctg tcctcgctcg tgaatgcaat gccgcatttt
    42421 gccttaatca aggacaagtt cagggaaaaa gatccccagg ccctcgttgc acgccttgtg
    42481 gatcattatt ccggggagaa cctggacctg accgatggca taagaatcaa caggggtgac
    42541 tcctgggccc tggtccgccc ttcgggtacc gagccccttg tacgtgtaat ggtcgagtct
    42601 gaatccgggg agagggcaga gcagttctac aaagagataa tgagccttat tcagagatag
    42661 cggcattttt tggatacatt gggataaaac ctttttttct attataaacc atataatgat
    42721 atattattat cctcgtctcg gatagaaatg caaataaaag atggcgtggc agatacacca
    42781 aaggtctctg gtatgaccat tccggtgggg ccagcggtaa tgaagaccat tgagatacga
    42841 attaccggga gagttcaaaa agtgggtctg cggaattgca tccggcacat cgccgggaaa
    42901 ctctgcatta agggagaagt catgaatctt cccgacggat ctgtaaagat tgttgcaagt
    42961 ggcgatcccc tgaccctcga caagttctct tccatgatat acgggtgccc gcgggccctt
    43021 atcagggaga tggagatctg cgaaatcccc ttcaggtcat tcgctgactt ttctgtcgtg
    43081 cgccccgttg agtgaatccg gttctggtat gtggatgata aaatcagtct ttttcatcag
    43141 tgattccttg agtgcgaaga catgagaatc tatgacatcc tgcctgatcg tacggatgag
    43201 tctttgcagg agagcctgta caaggtcgtc cgacaggatg caccggtccg ggccgcactc
    43261 gaaccccccg ggtgggagcc cctccctcac aaaggaacag acggggtcgt cgatcattga
    43321 cggtctgaaa gggtcacaga gatcatgcac gagtccggcc ttcccccgcg tcagaaaacc
    43381 aatatcaggg tcgaggtgtg ccccgattgc cgcaacgcac atgtttccga agaggagccc
    43441 gtacccgaac gaaaggaggg tattgacaac gtctgtatga ggccgggagg tccggcggcg
    43501 gaaaccaaga ccggcaggaa cagtacgggc aagaatctcg taatacatgt cagagataag
    43561 cctgtgcacc ctcctgacct cttcgaggcg gacgagataa tcgagttctg aaacactttt
    43621 ttcgaggatt tcgagctctc cctcgtaaaa gagaggatga tcaagctcct cctgcaacct
    43681 gacaagatag agtatccggg catgggcact tccctttgca atagcaagtg cagtggaatg
    43741 cggaaatgct ctcacctggg cctcacggac gatctggtcg tattgaaagc cgtatggtcg
    43801 gaggaaaccg agcggttctc catccgcttc gaaaaaggag actgcacatc cagcagagag
    43861 aagacgggag ataaccgatg aatggatggt atggcctccc atgacgagga ggtgcctgat
    43921 tgcagacaga ggaatctctt gtgtacagcc acgcttctgc actataagga tcttaggcgt
    43981 tgccttgata tgcgccccaa accctgatac cacataccag ggaacggtct ctctggtact
    44041 tttctcgctg ctctccatcc tggaaaaact ctctatgtta ctctcttgcc gggcataaat
    44101 acatcaatgc atcgtttctt ccggggagaa accggtgtgt tatggcgaag gtaatacagt
    44161 tttttccatg ccatgtcatg acctggcaat atttttcatc cttcgacgcg agtttatgaa
    44221 aaaggtacct ggtaatcacc agaagttctc tctcgtggtc atgagagaag gatacaatgg
    44281 tgaaaaatgg tgaaaatatg agaacaaagc aaaaaaaacc tgagacagga gactaatagt
    44341 catgttctgg gatgaaaaat acgagacact ttcaaagaaa gaccttggac gtctccagct
    44401 gaaacgcctc aaaaagacgc ttgtccaggt ccagaacgtc gatttttaca ggagattgtt
    44461 caaagatgca ggtatcaggc cggaggacat aaaaagcctc gatgatgtca ggaaattacc
    44521 gtttacaagg aaacaggacc tccgcaacgg ttatcctttt ggtttttttg ccgttccttt
    44581 aaccaaggtt gttcgtatcc ataccacatc cggaacgaca gggaaaccga ccgtcgtagg
    44641 gtatacaaaa aaggatctcc gtacatgggc aggtttgata gcacggaaca tgaccatggt
    44701 ggggctttct gaccaggata tcttccagaa catggttaat tacggtatgt tcacgggggg
    44761 tcttggcttc cattatggtg cagaactcat cgggatgact gtgattccca gtgccacagg
    44821 taacacccgc cggcagatag agatgatcca ggactttggg gttactgtta tccattgtac
    44881 cccgagttat gccctccacc ttgcagaagt tgccgaggag atggacgccc gcctcgactc
    44941 attaaagacc ggactgtttg gcgctgaacc ctggtccgac tcgatgcgca gggaactgga
    45001 ggacaagctt ggtgttactg cttacgactc ttacgggctt tctgagttgt ttgggccggg
    45061 tgttgcattt gaatgcagag agagggatgg tctccacatc tggcatgatt gttaccttgt
    45121 cgagatcatc gatcctgcga caggggaagt tctgggagag ggtgaacgag gggagatggt
    45181 tgttaccccg cttgtcaagg aggcaatgcc actcatcaga taccggaccg gggatatcac
    45241 gatgctttac gaggatggat gcatatgcgg gcgtgggcag aagatcgcac gtataatggg
    45301 aaggagtgat gatatgctgg ttatcagggg gatcaatgtg tttccatcgc agatagaaca
    45361 tgtacttttg ggaattcccg aggtgggtaa ccagttcatg gtctatgtgg acagggttaa
    45421 ccacctcgac gagatgacga tcgacgtcga aatcaaccgt gacttctttt caggagaatt
    45481 gaaggatctc gccagaatcc agaacaaggt tgtcaaggca ctccgtgatg ccctcgaact
    45541 caggacaacg gtccggctcg tggaacccgg ttctctgccc cggttcgagg gcaaagcaaa
    45601 acgggttgtg gacaggagga aagataccct atgacaagag catgggaccc gcgaatcgag
    45661 gagatgcccc tcgaaaactt aaaaaagctc cagtataccc tgctcaagac actcgtttac
    45721 cgtctgtaca gtttctcagc gttctatcac cggcgtatgg aggaggcaaa agtccatccc
    45781 gatgatatcc ggacgctcga agatatacag aagctcccct tcatgtataa acgggatctc
    45841 agagacaatt accctgacaa gctcttcatt gcatcccagg aagacctggt caggtaccat
    45901 gtctcctcgg gcaccacagg aaagcccacg gtcgtcggtt ataccgaaag ggatcttgaa
    45961 aactggactg tatcgcttgc gcgcgccctg gtctcgtgcg gccttggaag gggcgacgtc
    46021 atccaggtga gctatggata tggtctcttt accggaggcc tcggactgca ttacggtgct
    46081 gaacgtatcg gggcaacagt tcttcccaca agtgtaggaa acacggaacg ccagatcgag
    46141 ctgatgcagg accttggggc aacggcaatt gcctgtacac catcttacct cctccatatc
    46201 ggagaagttg cagaaaaaat gggaatcagc atcaggaaag aaacgaaact gcgtaccggt
    46261 atcctgggag cagaaccctg gtccgagaac atgcgccagc gtatccagga ctggctcgga
    46321 ataaaggcat atgacatcta cgggacaagt gagctctccg gcccgatgtt ctgtgaatgt
    46381 acagaacaga gaggcttcca tgtctgggga gaccttgcgt acgttgagat cctcgatacc
    46441 aagacacagg aaccgctccc gccgggagaa cgcggtgaga tggttatcac catgctccag
    46501 aaagaagcca tgccgctgat caggtaccgg atcggtgata tcagctctat cgaggaagat
    46561 gtctgcccct gcggccggac gcatccccgt gtccagagga taacagggag agtcgacgac
    46621 atgctgatta tccgcgggat caacgtcttc ccgtcccaga tcgagtatgc actcatgacc
    46681 attcccgagg tcggccagca cttccagatc atcgttgatc ggaagggggc actcgatgac
    46741 atgctcgtcc aggtggaggt tgccccggag gctttctccg acaagattac ggatctcatg
    46801 gcgattcgga gaaaggtcga gcacaagttg cgcaacattc tcaatgttgg tgtgaacgtg
    46861 gaactggtcg aaccagggtc actcccgcgg ttcgaaggaa aagcaaagag ggtaatcgac
    46921 aggagaaaga tctgatatgg gagtcaataa cttcgtcatt aagcagatat cggtcttttc
    46981 cgagaacaag cccgggagac tggcagcaat cgcccgggcg ctgcaggaag agaagattaa
    47041 tatcctcgcc ttctcaattg ccgaggcaga cgggttcggt gttgtgaggg cactcgtgga
    47101 cagcccgcag agagcatatg aaaaactcac gaagatgggg ttcaacgtcg cattcaccga
    47161 cgttattgcc gtccagatga aggatgaacc cggtggttta tacgagattg caaaaattct
    47221 cgggcaggga ggaataaaca tcgaatatgc ctatgcatac tcgggcaagg aaggcgccgt
    47281 tctcattctg cgggtcgaca atgtcgaggc agcaatcgct gcagtccgga aaggtggtgc
    47341 aaaactgctc gagagttccc tcttccagta atttctccta ttttttttcc cagcggatga
    47401 ggtctgatac acgggagagg gtacttcccc tccggatctc ctcccggatc ctctcctctg
    47461 tcttcttgac ctcgagtgcc cttcgtgcga tctctgcggc acgttcgcgg gggatgacga
    47521 caaccccgct cgcatctccc gcaatccagt ctcccggccg cacggtctgg cctccgcacc
    47581 tgacctctgc attgatctcc ccaaaccctt tcggctcccc ggcatttggt gttactgccc
    47641 gcgcaaaaac cgggaaccca agacgccgga tatcatcgat atcccgcgcg gcaccgtcaa
    47701 taacgacacc ggacaggcgg cgtttcatcg cactcatcgt ggcaagttct ccccagcatg
    47761 caacgtgtgt cgcgccatca ttattgatta ccagaacgtc accgggttcc gcaatgtcaa
    47821 ttgcttcgac cggttttgcc cagtctcccg caaagccctg gactgtaaca gctcttcctg
    47881 ccatccttgc ttccccgcag agagggatta ttccggccat tgcccccttc ctgtgcatgg
    47941 catcagagat gttgggggtt gacaccgatg agagtatatc ccggactata tcttccgaca
    48001 aggatctctt ctcccttgcg agtgttggat tgtccagagc ttcacggacc atccgtgctg
    48061 atgccgtcac atcggccgac ttggtaatcg cactccccac aatgacgata tccgccccgg
    48121 cagcagctgc ctgcggcgct gtcgttgcat cgaggccacc ggccgctgca aggggaattg
    48181 ctatcgcgtc ccgtatggct gatagcacgt ccaggggact ctttccactc atctgctggt
    48241 cgatgccgac atggacattg acgatgtgaa cacccatctg ttccagttcc cgtgagcggg
    48301 caacgggatc aggtacgctg atcaggtcac ccatcagcct gataccatag agatcggctg
    48361 ctctcaccgc ttctgctatc acggcgtcat ccgaaccggc aaggatgcag acaacagatg
    48421 cacctgcttt tgctgccatt tccacttcaa gtgcccccgt gtctgcaatt ttcatatcgg
    48481 ccacgatctc gcgtccagga aacatggcgt ggagagtccg gactgccgcc atcccttcgc
    48541 tctttatcag gggtgttcct gcctcgagcc agtcagcacc gccagccact gcctctgaag
    48601 caatctggac tgcacggtca atctcggtga tatcgagcgc aacctgcagg atcgttccct
    48661 tcttccgcgt gcggtcaggt tttcctgtct ctgtcattcc tgcctcacgg gatggtctca
    48721 tgggaaaaac ccccgtccag tgagccccgc cttatttctc gctgtaagtg tcaaagaagg
    48781 tcacatcatc gaggatcttc ttcttctgca ttgaaacctc ggccgggtaa cccgcagcca
    48841 cgagcgagac cagggtatac tccgcaggaa cagagaggag tttccggatg tcttctgcat
    48901 acggcttttt atcaccggca acccagcagc ttccaacccc atatgcccac aatccgatga
    48961 tgaggttctc tgttgccgca caacagtcct cgaggtagta ttttgcggtc ttctctccaa
    49021 atatggcaaa acagaccgcc gcatcagcaa tgaacttccc gtgatctgtc attccagcaa
    49081 tcttctcgag aagagacctt tcacggacga caccaaagag ccagggttgc aggttcatcg
    49141 ccgtcggggc ctgccgggca cactcgagga cgtcgcgaat cacgttctcc tcgacagggt
    49201 ccgacttgta tttacgcaca ctgtgccgag acttgatgat agtggtgccg acgttcatgg
    49261 aaaacccatc ggtgcctgag gaaaaaaaag tgactcttcg tgcgattatc taagggagtg
    49321 ctatccctgg cgctccctgc gctgatggag aacgaggact gcgcttatta atgcaaggaa
    49381 aagggttgcc ggaaggaggc cgggcgcacg cgtcggtctt gctgacaaca tgggggggac
    49441 ggtctctgcg gtcgacggaa ctgtcgtcat gactgatgtt tcgactgtgg ttccgctttc
    49501 caatcgatca gtcgtcccgg gagttgatgt gactgctgtt gcagtctccg taactgctgt
    49561 tgttgtcatg gttgcaatca ggggattgac tttctggagg aggaaccgga cctgttcact
    49621 ctgcgacttt cccgtcacgg gataattgtc atgcatatta tttgcctcgc accgcacgga
    49681 gactatgtag tctcctatgg gatattcccc cgaacccgtc gcccagaccg gaccgctctc
    49741 gaatgtaggg gtggatacca ccacgtctcc cagtctgtat ccgccaaggg aagaaaatga
    49801 caggccgccg ggtccggtaa tctctattgt gagggggact cccgtgcaac ccttgcgatg
    49861 ggagaagacc cagaggttcg tatcaatccg aaaaccggca atatccccct tgggaaccca
    49921 ggtagcatcc ctgccgacca caaaaccgga ggtgtagtca acgatacgta cctggatcgt
    49981 cggatctccg acgtagaaag caaggttatt ttcggggagg gtgaaccagg gacctgtttt
    50041 tcccaaaaag acagatggtg caacataaaa cgaggaggga tccgctaccg tcacctgcgc
    50101 ggcgggcaca ctggatacac ttcctcccgg tccgtagtag gcaatctgcg atcccgcggt
    50161 cactcccgtt ccggttatat ccaggccctc ctcgccgatg aagacccaat cccctgccgg
    50221 aattgttcca catgctgcca tcgcgggtaa tacaagggag aggagaatca ggacaggaat
    50281 gccggaaaga cgagcaatat gtattttgtt catacggtgg aatggcataa tgtctgatta
    50341 atacctttct cccgccgttc aggaaggaac atgatcgtca tcccgggatg agtcccgtga
    50401 taccattcca catgttcgag aatccctggg atatgaggac tgtaggatcg attccaagga
    50461 tcgggaatat gaagatgaaa tagaggattg tcccgagcgt gctccccagg ttggcaagtg
    50521 cagccacgag gacaaccctg aaaaggggga ccttcatcat cgcggagaaa ctctcggcct
    50581 cgaataccct ccggaaatca gcgggggtcg gtttccgaat cttcgcctca acgattgcgg
    50641 caaaccatcc agccgcaatg agggggttca aggccgtgaa ccatgatact ccaaatcccg
    50701 tgagagcaga gagtggatgc ccgcgggcgg cgagcgtgaa ggccgcggta agaatgccgt
    50761 ggagaagaac ccagtatacc agagcggaaa agaggacctc cattcctacg ccggaaaatg
    50821 caatggcaag gagaagaagg atgaagagtg ccgtcacacc ggcgccgaag atctttcccc
    50881 atggccggga tctgatatcc gcatccagtt cttgcttgga gaggatctcc ccgggagatg
    50941 caagcagctt ctcgacaccg gccacgtggc ctgcaccgag gacggcaagt atcctggtgt
    51001 gtcgctcttt caggatggcg agattgtgtg cgagatacga gtcccgctcg tcaatgaggg
    51061 cgcgggcacc gttgggagaa aatttcctga actctttcat cgccatgctg accacgtcct
    51121 ccttcttcag ctcctcgacg tctatctcct cggaatccac cgtggccagt gaaaggacga
    51181 gagcatagag gagttttagt ttctcgaaaa aagagagcga attccagaac ctcctcaacg
    51241 taattccgat atccctgtcg atgagtgcaa cggggatgtt ccttttttca gcctcctcga
    51301 ttgctgcctt catctccgca ccgggttcaa ctcccatgtc aaggccgatt cgcctctgca
    51361 ggtaggcgag tatccactgg acaaggagct gggtgaaatt ttttgcctcg aggacatcct
    51421 tgacggacgg gtcacgtgcc tgctttttta aggcggcata ccgtgcaggg tcgagttcga
    51481 tggccactat ctccggggag aattcctcta ttgcagacct tacctcctcg acactttttg
    51541 cagagacatg cgctgtgcca acgatccgca gggttcctgt cactgcctgc acaccccttc
    51601 cgcatcaacg ataaaccttc ccggtccggg aggaatcgtg ggaaaaacag cctggatccg
    51661 acggatctcc tcttcctctt cggccctcct ggtaagaaga tcgcgggcaa tgcggacggc
    51721 gtcctccctt gaaatgggtt ttcccagtcc tcggcaggga tagaccctca acccgcttcc
    51781 ttcgagcatg aagggatacg tcctgcagat cgaaggtctc acggcgtaaa cctggcaaaa
    51841 agagccggat aaaaagcgac agttaccaca gaaacgccgt agtacccgcc cgaatgtaac
    51901 gatgcgattg ccaggaagtg ctacggtgtc cgggtatggc tcggcgactt cggtgacctc
    51961 gagaccggta aattctgaaa tttcccttat ttcccttgga aagaccatga cgaggttatc
    52021 gtccccggca ccgggtctgc agcagtcccc gcaccgggtg catgaaaaac cgattctcac
    52081 tatctgttcc gcaagggtac tctcctcatc ccggtaatcc tcgcgcgtca tatcccatac
    52141 tccctgcata tcgcgtcaaa gttctggtat actctttgtc cgtccttcgt gtggctgact
    52201 tcaggatgcc actgcaagcc aaaaattttc ttttccgggt atgcaatggc ctcatgcgcg
    52261 catacaccgg agcgtgcgag gagatgaaaa ccggggggaa ccactgtaac ctcgtcggcg
    52321 tgcgaagccc acacgagtat tctctcgggg tacccctcga ggattcctga tctctccacc
    52381 agctccacct cgaccggccc ataacccccc atgcgacccg gggcaacgct ccctccaaac
    52441 tcccgtgcga tgatatgaag gccaaggcag atcccgagga cggggacacc gaggtgaagg
    52501 aagaggggag aattgccgca cttcccgatg tcgggaccac ccccgaggac gatgccccgg
    52561 catgagcctg ccacctcttt tgggggaagg gtatttgaga ccatccgcgc atcgatgccc
    52621 aggtcgcgga acatcctcaa aatgaggtga ttgaactgcc cgtaattatt gacgacgaag
    52681 atggggagca tggttcttca caaatgtggc gcgtaatagg tgaaaatgtc tctgctgcag
    52741 gtgttgacta tacggaaaaa aagaggccct cattgcagac cgaacccttg ttttttactg
    52801 gtaggaggat acagtcccga gaatcttttt tctgatatcg tggggggaat gccccatgat
    52861 cgcagcaagg aacatggcgc cacctgcccc catcccctcc tttacctcac cgatgcagta
    52921 ccgtgcaagg ccggcatgtc ccagatcccc gaatcccggg tcaacatagg caaccgggac
    52981 gccaatgcga ttggccacct cggagaaatt ggcagacgga tcgtccctta cgtagacggt
    53041 cgtggcaatc atggggagtg gaattgagag agatttcatg agggctgcaa cagcgagcat
    53101 ctgggtgccg cccgcaagca caagcctgcg ccccctgttc ccatatccca tcccgatacc
    53161 ggcacagagg gggatcatgg ggtcaccgca aaaccgggct gcatcgagtt gggaaagagg
    53221 catatggtca gctatccgcc gaaatactgc ttcccagacc gcttccttca tcccgacagg
    53281 gttatcagcg taactcgaac tgacccgggc aggatatccc agcgcacgga gcacacagag
    53341 ggctgttgtt gtgcctccgg ggacgcactc cccgataacg agcacgtcac acattcgcga
    53401 gagcattgcc ccgatgatgc gtccctcctc aaaaaggtct gcggaacgtg gaacggcatc
    53461 agctgaccgg ggatcctgtc ccggttctcc atagacgtcc aggcagggta cggtagggtg
    53521 gtgaacaagc cctgcattga taaagagtgg aataatcccg cacatatcca tcatcgctcg
    53581 cgtgatggat gcaggggtcg ggcacccggt cggagtgtcg ggtcgtgagg gcatgctcgt
    53641 tatcctcccc ctgagaacca gttctgcatc gaggatgggg gtaaaaaggg ttttttccgg
    53701 gctcgggccc gcacccgata tcccggggac gacggaaagc atcgtgttgg caaggacagc
    53761 tgcaaaaaga ggctgcttgg gcgaaagtga aaaggtgtct gaaacgaacg gcatggacgg
    53821 tctctccctc ttctatttcc ttcggaattc catgaatatg acggccggtg acgggggaca
    53881 accatcatat caggaaaaag acatatcact cctgctgaca gggcacgccc cttatgcata
    53941 cccgaatggg agggtatttt tccatgtcgg agtaatgcgg ggctaccgga atggtgcaca
    54001 agatgtttga tattactggc agattgcagg aaaagggcat cgatatggag aacatgctcg
    54061 atgccgcgat ggaactctac gtcccgcacg ggctctctcc tgagattgcg aggccaagga
    54121 tcggacagat gatggatcgg tatatgaaag atccaaatgt cgcctccctc ctccttgcgg
    54181 ctgttctcct cgaggacgaa ctctattgga agaaaaaaga ttccccgata aaggacgacc
    54241 ccgtattcct gctctcggac gagatcattg ggatggcaat tgcagaatgc ataggtggga
    54301 cttatgcgcg gttcgaattt acccgttacg atcagaaaaa gccgggtgta ctccggtcat
    54361 tgggcccttt ccttgacgat gccgtagccg gactcatcgc cggctgtacc tcgaggttct
    54421 acagcgaatg tgtattaact ccctaatcgc cctcctccag ttcacgacaa ttcttcccct
    54481 gggcgggatg agggatttta aggattttgc gaggcgatcc tggctctatc ccgttgcggg
    54541 ttacgttgtc ggggggattg ccgctgcggg ggcatttctc atcggaccac ccctgctcgc
    54601 ggctgctgta ggaatcggcc tggtcttcct catctcgggc tgtaaccacc tggatggtct
    54661 gatggacctt ggcgacggtc tcatggcgca cgggggatgc gaaaaacggg ttgctgccct
    54721 caccgacagg caggtcggga caggtgcttt tgcgctcgct attgtcgtca cgctcgtttc
    54781 gttttcgtcg cttgcgtcag tcccatccgt tgccattgca ctcctgatcg cagaggtcgg
    54841 ggcgaaattt tcgatggcgt ttctctctac ttttggaaag cccttccgga atggccttca
    54901 cgcgataatc cagtcacaat caaggcctta ttttcccctg ctcgcaggta tcctctgtct
    54961 gccgctcgtc cttctccccg taccaccgtc aacacttctc gctgttgctg ccgccatgat
    55021 tctgtgtccc cttatcctcc agatcatcgc ctgcaggctc tttggggggg tgaacggcga
    55081 cgtggtcggc tctgcaaacg agattacgag ggctgtcatc cttgcggtcc tctgcctgtc
    55141 agggtagcag aacgcgcaca tttttccttg atcgggggag aggtacacta tatgcccagg
    55201 gagatagccc ttcacatgcg cggtggtgtc atcaccgagc gtgaccccca gttctgcaca
    55261 atccgcaccc gtattccggc cggtatggtc aattcacaga tgctgagggg tcttgcagat
    55321 attgcagaaa aattcagtgc tcccggcctg cacctcacaa cgaggcagac cattgaaata
    55381 ccgggtatcg attcccgcaa cctccaggag atcgccgccg aactggacag aaacgggaca
    55441 cccatcggtt ccgagagaga cgaggtcgtc aacgtcactg catgtcccgg tctcccgcgg
    55501 tgcgtatttg caaatatcga ttccatgaat cttgcaaagg ccatcgataa ccgtcttttc
    55561 ggccgggaaa tgcctgtcaa gatacggata tcgatttcgg cctgtccgaa tgcctgcacc
    55621 agtcccatgc tcaatgaaat tggcatcata ggcaggattt cccccataag aactccgggg
    55681 ctctgcacgg ggtgtggcac atgcgttgag tactgcaagg aaggcgctat atctatcaag
    55741 aaaggagtat cagtgcttga cccggccctt tgtgtccagt gcggcacgtg catccgttcc
    55801 tgcccgttcg cccttctcaa gtcgtccggg gaacactaca tgatatccgt cggcgggaga
    55861 aggggcaggc atccccgtat cggacgggaa ctcgttgtcg tgaggacgcc cgaggcagtc
    55921 gttgatgtcg tcgagaaggt cgtccagtgg gtatacagga gagcgtggag cggcaggctt
    55981 ctttctgaac agctcgagga catccggttc gggcagctca gggatgaaat acggaatatg
    56041 ctcccggctt ctgtcctctt cgaggatgtc tgatcacctg attcggtacc gtgggacgaa
    56101 tccggtgttc ttctcgtccc cacattcgat tgattcgcca tccctgatga gctggttgaa
    56161 ctggagctgg gcattgagga gtgcctcgtc aggcactgcc ccccgtttca tctcctggag
    56221 caccttctcc tgcggtgcgg gataaagccg tgaaccaacc cttatgcctt tgcagtgctc
    56281 acagaatgca cagtaacgat aaactgatac ttcacccgta aagcacatga cagtggcgcg
    56341 gttcccggtc ttatccttgt ttatcggcag ggtcttcatg gttcagaagt gggttttata
    56401 ctccgacaga tatgattctg tcgataataa cctccttttt ccgggaaatc cgtctaaaat
    56461 ccgtcaatcg aaatgattaa taggtatccc tttcaaataa attatactcg aataaatggg
    56521 ctgaactctg acaggctcat ttttatcgga ggaatgacat ggcagcagaa aagcctcaca
    56581 tgaatctggc ggtcatcgga cacatcgacc atgggaagtc taccacggtc gggaggctca
    56641 tgttcgagac cgggaccgtt cccgcacaca tcatcgaggg ataccgcaag gaggccgagg
    56701 ccaagggtaa ggccaccttc gagtttgcat gggtcatgga caacctgaaa gaagagcgcg
    56761 agaggggtat tacaatcgac attgcacaca agcggttcga tacgccgaaa tactacttca
    56821 cggttgtcga ctgtcctggt cacagggact tcgtcaaaaa catgatcacc ggcgcctccc
    56881 aggcagatgc agcaatcctc gttgtcgctg cacctgacgg tgtcatggaa cagacaaagg
    56941 agcacgtatt ccttgcaaga acactgggta ttggccagct cattgtcgca atcaacaaga
    57001 tggacatggc caagtacgac cagaaacggt tcgaagaggt gaaaaaagac ctctccgccc
    57061 tgctccagat ggttggctat aagcctgcag aaaccctctt catccccatc agttcccttg
    57121 caggtgtcaa catctccaag aagagtcctg aaactccatg gtacacaggc ccgacactcc
    57181 ttgaggcact ggacaccctt aaagaacccg aaaaacccgt ggacaaaccg ctgcgccttc
    57241 ccatccagga cgtgtacagc atcagcggta tcgggaccgt ccctgtcggc cgtgtcgaga
    57301 caggtatcat gaagaaaggg atgaaagtga gcttcatgcc cgccaacaag gagggagagg
    57361 tcaagtcaat cgagatgcac cacgaggaga ttccccaggc cctgccaggc gacaacgtcg
    57421 gattcaacgt gcgtggtatc gccaagggtg acctccgccg cggcgacgtg accggaccgg
    57481 cagatgctcc cccgacggta gccgatgagt tcactgccca gatcgttgtc ctccagcacc
    57541 cgagtgcaat cacggtagga tacacccctg tgttccactg tcacacgacc cagacagcat
    57601 gcacgttcat cgaactaaag aagaaactcg acccgaggac agggcagacc aaggaggaga
    57661 acccgacatt catcaagacc ggtgatgcag caatcgttca ggtcaagccc acgaagccaa
    57721 tggtcatcga gaacgtcaag gagatcccgc agctcggcag gtttgccatc cgtgacatgg
    57781 gctccaccat cgccgcgggg atgtgcattg cgattacccc caagcagatg cggtaaggta
    57841 aaggggttct atccatcctt tttggtgaga gaacatgcaa aaagccagaa ttcgcctgac
    57901 aggaactgat ttcaagaaga tcgagatggt ctgcgaccgc atccgcgaga tcgcggagcg
    57961 cacgggcgtg aatctggctg gtccgattcc gct
//
LOCUS       DAOOJU010000010        56559 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_654_length_56559_cov_15.957136, whole genome shotgun sequence.
ACCESSION   DAOOJU010000010 DAOOJU010000000
VERSION     DAOOJU010000010.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 56559)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 56559)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56559
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_654_length_56559_cov_15.957136"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1217
                     /locus_tag="PK679_03990"
     CDS             <1..1217
                     /locus_tag="PK679_03990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55150.1"
                     /translation="ALWIVIIATLAYSTFLAPSPAISTQFNLSVSGNEAFITHTGGDP
                     LPCDSVAILLNDREVPFPKDSIECPWSIGETVSISLPRSGSPVTIRIVSSASPKGSRE
                     LFSAEIPAMTPLATPSPPPTPATPGTTPATVVPTMTPTPAPTLIPIDTLGAPVAAFTA
                     EPREGPVPLTVRFTDTSRGIPGEWSWTFGDGETSTIQNPVHTYTKTGSYQVGLTVRNA
                     FGGHTRISQGFITVTPAENRDVYLEAQRDARVPAGGFLEFTVREGGSRVKIGGTVIDL
                     PPGARVRLTLPAGGKGKVSIRSGKILGFSFENTVLSIDGEVRGQGEVREISVQGYDDL
                     VSSLVLVVSQGPGTVRLLESGIPVDLPSADSPLLLISARPDPAGILNIDCFRPDSAFF
                     QGAVSGYSFGPV"
     gene            1423..2937
                     /locus_tag="PK679_03995"
     CDS             1423..2937
                     /locus_tag="PK679_03995"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55151.1"
                     /translation="MDRESAISKNILLALVAAVAIILVVIVAVFIFFPPQPDVVPQFT
                     ATIERSGNTVYIYHDGGDPLQSSRTLIRINGQTIPPNYISFLHSQDWPWTQGKTVRVL
                     YDGPGTPDLVEVVYSGSKGEIVVFSDRAPSGTPPTIAVTTVETVPVTATPAPSEVIPV
                     VTASPPGPVSPAPPQAGFIGEPRTGQVPLIVRFMDMSGGSPTAWLWNFGDGETSTEQN
                     PVHEYARSGTYTVALTVRNQFGTGQKVEKDYIKAGILPKAQFAVVPSEGEAPLTVQFN
                     DLSTGVPTAFSWDFGDGSGSVEQNPVHTYVKEGDYTVSLTVSNQFGSDTRIQSGAVRV
                     SPAKKVDVLLSGSRRGTLSTGFIQFTVTGRPAWIKIGGTRYDFSPQDIVQVFIDKSES
                     GTIDVNANGLTGLKFDAARLFVNGNPVRSGIVNDINVPSYSGVSSTLVIEIAPGDQTM
                     TLFVDEGRILSAPDQKILISNLCENSDGQMSLRIIPGALEYRGGARGFSVVPVS"
     gene            complement(3124..6438)
                     /locus_tag="PK679_04000"
     CDS             complement(3124..6438)
                     /locus_tag="PK679_04000"
                     /inference="COORDINATES: protein motif:HMM:NF024816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55152.1"
                     /translation="MDGEIYYNRGIAYHKKGLFDEAIADYTRAIEINPDDAEAYHNRG
                     VAKAGKHDYPGAIEDYSAAIRINPHFSEAFYNRGVAYSLLNRPENAISDFTSAVNLDT
                     DFVEAYYNRGLEYARIGEYELAIADFSKAISLNPSYAAAYNNRGVIYARRGMHEKAIE
                     DYTRAFELDPSFSEALFNRGIEFSRLGHFEDAIADYTRALEITPEKADILYNRGLAYG
                     KLGQSEAAIADYLQCLEKNPAYAEAHNNLGVEYSHLGLLETALDHYAKAIEINPSFVE
                     AYNNRGVLFNRMGRFDEAIAEFSRALEIISEETQAEAVTAQPEASLSGMAAETAPGQG
                     VPGEEEKGETTVPPVEELVEDPAIRQLTDEINRSPDDPELYNRRGVEYSRLGQSEKAI
                     EDFTRAIDIDPGYIEAYFNRGNEYDRLGMVDEAIADYTHALKINPKFAEACFARGIEY
                     QKANLSDRAISEFTKALEIRPAYPDALYQRGCEFAKIGLSDMAVRDFSRALEIRGQFF
                     EALVARAEQYSRKGLSERATEDLTAALALEPTSAGLYVRRGIEQSRSGKIEEALADFS
                     KAIGMEPSNADAYFQRALILQKQGRFEESASDISRVIELRPADAQAYLIRGRQNSELG
                     NSSEAIADFSRALEIDPRLFDAYIGRGQERSRCGQAEKAVEDYSNAIRLNGRSVEALT
                     ARATEYSRLGRYEDAVEDLSRALEQAPGDVSILLARGLLYERLGMIDEAIADYSKVIE
                     IDPGHEKAYINRGNLLAGRGLSSEAIADFSRVIEINPGNAVAFYNRGIEYGERGMLDE
                     AIKDLGKAVMLRPDLAEAYYNRGVAYHKKGMLEEAIADYNRALELSPDNEKAYNNRGN
                     AHAALGMYDEAIEDFSRAIEINPDNPTAYYNRGIEYGKKGLIEKAMEDFSRAIAIKPD
                     LAEAYYNRGVAYQRVERYEEAIADYSRAIQISPANEKAYNNRGNAHAALGMYNEAVSD
                     FSRAIEINPDNPTAYYNRGIEYGKKGFFDEAIADFSKAVGLRPDLAEAYYNMGNIYYN
                     RNMCREAIREFDRALGVKPGYARAFLNKALAYEKLSMTEEAIAAYEGFLKFARNESKE
                     LVDFVSQRLRDLSLSV"
     gene            6799..7674
                     /locus_tag="PK679_04005"
     CDS             6799..7674
                     /locus_tag="PK679_04005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55153.1"
                     /translation="MAGLIVPAWADIQSVVLYKTDFSENPGWMTNSPSRYYWDSDREM
                     YHFRTEGGTNGYAYVPLRYDDQSFTLDYDVIVLVSQPNSAFRFGLTSSEMDFTRGTTI
                     LSALENGKYGKLFSLRVIDQNNQLREISSYYASYCGSLTGCDTVEFRENTTYHVTVRY
                     NRELRNADIKVVRKDTGEVVFGYFVPVAKELLFMDRLAITTKGDYLPGSYSEGYIDNV
                     ELSIMTQVTPTPTPPPATVTATSTTATTIPTPSPERTTSPTPTQTAPVPALIVVVSLA
                     VSGGIAVSLRLKKDA"
     gene            7731..8594
                     /locus_tag="PK679_04010"
     CDS             7731..8594
                     /locus_tag="PK679_04010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2099 family protein"
                     /protein_id="HPC55154.1"
                     /translation="MTEPARDEHVIEAIGKARVVIRNGKVISVGEPLISECPLARRFG
                     KPVPVITPGAIGENMEYRIRAFGMCTPDRAIEADGDYVGFGASELLSCGLSSGLLDCV
                     VIACDGAGTVIVTRPSLVQGIGGRMSGLVRTSPIPQVIRRIQEKGGTVCDPAAASIDQ
                     AGGVRMAREMGYSRIGVTVASAGDARSVREEYPGTLVIAVHTTGVTEEEARILATSAD
                     IITACASRHVRNVAGPRALLQAGVSIPVFAMTRAGRDLILEKVRQAPARVVISNAQLP
                     ATHGVEPQPLV"
     gene            complement(9816..11165)
                     /locus_tag="PK679_04015"
     CDS             complement(9816..11165)
                     /locus_tag="PK679_04015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55155.1"
                     /translation="MKEPTFLIGFDKFFEVAGKSDQSYYIHNYLKSKLEPKSIFIEEN
                     YIDKDYLIDFSKFYARSFNIDKKFTTRLHFFNESIENKEFYEGLKNFNKDFHDKLKKA
                     YLGFTVIKPIMDRENQPFIGRTLLRTWPRDDNGELREYLTNTFHVSLYGIDLSIDSLP
                     FQSQDEAVGGCATTACWTALYPLSKQFETPKLSPVEVTETSISFPTLERNFPSKGLTL
                     HQMKSQFNALGLETEFINVEKIQTNRKDVSIDDFIGNAIKAYLDYGIPIIGALKLKKE
                     GRPDPEKHAVVISGYRHRDGKITELYIHDDAIGPYCKTKLKESICNWENEWITEKKYS
                     EINLQMLLIPIYHKMRLSYIKIYRVFLRNQRMIEERKKEREMKDEYSHELKLVKLNDY
                     KRFLLDKQFNKKKDFLCKNYPRFIWIHRIKSNGQLYIDKLYDGTSVYPSEIGVIDYN"
     gene            complement(11178..11489)
                     /locus_tag="PK679_04020"
     CDS             complement(11178..11489)
                     /locus_tag="PK679_04020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55156.1"
                     /translation="MPPESDERLGEWERKKEWHFLVSYFLDSIIVTSEFFLIDFKYNN
                     TSKTNCLSSMDRRGEKMTDFKDDLIRILTLDSKIKNEAEEWYREFTTMSMEDLFEPFT
                     V"
     gene            complement(12144..12228)
                     /locus_tag="PK679_04025"
     tRNA            complement(12144..12228)
                     /locus_tag="PK679_04025"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12190..12192),aa:Leu,seq:gag)
     gene            12417..12917
                     /locus_tag="PK679_04030"
     CDS             12417..12917
                     /locus_tag="PK679_04030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator of amino acid metabolism, contains ACT
                     domain protein"
                     /protein_id="HPC55157.1"
                     /translation="MWSEIIREFSDSPSQAKVVTFLLENGFSVNERGRINCNGLEIPS
                     TQVAKAIHTDRRVVDATAQRILSLPLHRTVFSHMRVTPDLSRVADHLGLSVMTIYPRD
                     ATEKGIVSEAVRVISEAGLSIRQIYVTDPLLSEDPKLVIIIEGDFPPRVIEGVRHLPQ
                     VRKIVL"
     gene            complement(13004..13504)
                     /locus_tag="PK679_04035"
     CDS             complement(13004..13504)
                     /locus_tag="PK679_04035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HPC55158.1"
                     /translation="MPDRRDEWRELLERAGCSRRVIRHCDTVCDLALGFFVPGIMDRE
                     ILLTGAMLHDIGRGFTHDLTHAQKGAAYCREQGLPDGIVRIVECHTGAGLTADECTLL
                     RLLPVDCIPRTPEEKVVANADNLVADAHVIGIGERMMRACNLPRKVKRRIFRLWLEME
                     LFRDCA"
     gene            complement(13497..14009)
                     /locus_tag="PK679_04040"
     CDS             complement(13497..14009)
                     /locus_tag="PK679_04040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor"
                     /protein_id="HPC55159.1"
                     /translation="MEDILAIPAIHTYLDRLVGEEGISLIESFPGDGEYSDEELAEKT
                     GINLNSVRHTLYTLYEKRLAEYRRIKNNETGWLTYLWQLRMDRIYEVIAEDMAQVLEK
                     LEARARFEEENDFYICKSCGDIFTFDMAMDSEFKCPSCDNPLEHFDNEILLRALKKRI
                     QAIKESLCNA"
     gene            complement(14017..15093)
                     /locus_tag="PK679_04045"
     CDS             complement(14017..15093)
                     /locus_tag="PK679_04045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HPC55160.1"
                     /translation="MNPSILVMGFSTRHVAQSAHEAGYTVYAVDHFCDQDLSWYTRDR
                     IRFDELADLPSAVQEMCGKYRIDWAVPTSGAETLAHGLPVLGISPEVAARFLDKVSTQ
                     EFFESLGVPVPRLLPDGQYPAMIKPRSGSGGWRNRVVCSREEESLWHEEFEGMESISQ
                     EIVSGIPASVSCLADGKGNARALAANRQILRDEGVSAFGFCGSQTPLEHPLAPRMIAY
                     AEKVAASSGCCGSLGVDFVIGEDIHAIEVNPRFQATLDTVERSLGLNLFSAHVRACRG
                     ELPDKVPNPSCFCIRRILFAERDCTISGDLSGLSPAVSDIPWPGTFFEEGQAVVSVYG
                     WGPTPESAMHHLDRHIRRVRQYIR"
     gene            complement(15090..15614)
                     /locus_tag="PK679_04050"
     CDS             complement(15090..15614)
                     /locus_tag="PK679_04050"
                     /EC_number="2.1.1.206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(56)-2'-O)-methyltransferase"
                     /protein_id="HPC55161.1"
                     /translation="MKDVRVLRLGHRPERDQRVTTHVGLTARALGARGMYLAGRDAGI
                     VAGIRDVVSRWGGDFFVEDGVPWKKCIREWKASGGVVVHLTMYGEPVQERVADIREND
                     RILVVVGAEKVPGEIYLLADYNIAVTNQPHSEVAGLAVFLDRLFEGRELAWEFPGARI
                     RVVPSPRGKRCEEI"
     gene            complement(15611..15928)
                     /locus_tag="PK679_04055"
     CDS             complement(15611..15928)
                     /locus_tag="PK679_04055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HPC55162.1"
                     /translation="MRYLMHQQAMREEDLDWEVYHLIVADPARDAGFLAAHLGRSPSE
                     IQASLQRLERAFLIEQGDGGSFRVLSVQEMLIRCQARYCRDIPFVIEGGVIKLKNDRE
                     PDE"
     gene            16096..16509
                     /locus_tag="PK679_04060"
     CDS             16096..16509
                     /locus_tag="PK679_04060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55163.1"
                     /translation="MQQEDEGKLSQGELADIADDILERVGEDVDALAGELDMLDPAVR
                     RQLLVSDFLNAFQVYYYFYRKAPGELELERLLLQPASALAHGVLLTELDLFVVMFRVE
                     EGRPIISVGDGERILANFREKDAYDKALRFIDESA"
     gene            complement(16470..16682)
                     /locus_tag="PK679_04065"
     CDS             complement(16470..16682)
                     /locus_tag="PK679_04065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55164.1"
                     /translation="MAQKILVVDDNPGITGILKMFSGMEGAIVHTAAGGEECLAMVSR
                     EKHAIVLPDIVMCIHADSSMNRRALS"
     gene            complement(16693..17403)
                     /locus_tag="PK679_04070"
     CDS             complement(16693..17403)
                     /locus_tag="PK679_04070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0280 family protein"
                     /protein_id="HPC55165.1"
                     /translation="MIRHRFAFRETIATILAERDEDVEAARRGLMSARQDLERYIAGD
                     PFFVATLEPYPLHTGIAIVDRMADAGVSAGVGPMAAVAGAIARAGVEEMIRGGARLAV
                     IDNGGDIALVSDRTLTVGIHAGTSPYSDTIAFRVPPQDRILGICTSSATVGPSISFGS
                     ADAVCVISPDPCLADAWATALCNSVSREDQHMLGRVPWDRIEGVLVIEGNWIHKEGTL
                     PPIVRARVDRDLVTGGPW"
     gene            17505..18173
                     /locus_tag="PK679_04075"
     CDS             17505..18173
                     /locus_tag="PK679_04075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HPC55166.1"
                     /translation="MVSWMHAGHRRSRTGARRLPAYIVVLCVEWPGLERLQDLVAQEV
                     GLARDQRFFPHVTLCGPLLLHPGTDIVAVLDRAVASLSMTRIVHPVDLHLFRGKRGLA
                     VSLLLQEDATLTAFARAVSDALAPFSKKSNPIDIPPSKRILHISVAVNLSRQKGELVF
                     SKLADPGGKPGREKELLFRETPPRITRMALIRRGALWKAYDLFQKKWIGRNGLFEAEK
                     RGRR"
     gene            complement(18205..18597)
                     /locus_tag="PK679_04080"
     CDS             complement(18205..18597)
                     /locus_tag="PK679_04080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC55167.1"
                     /translation="MKLLVTFSRKEGRKPIIAQVVRDTGVLVNVERALIDSSEGEALI
                     DIPDESCRIVKDRLTDLGASVRILEEEIILDETECVDCGACISICPQEVFSFDSDFRL
                     QMDARKCVLCGRCIEICPHRALSRKGPA"
     gene            complement(18594..20102)
                     /locus_tag="PK679_04085"
     CDS             complement(18594..20102)
                     /locus_tag="PK679_04085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine biosynthesis protein"
                     /protein_id="HPC55168.1"
                     /translation="MRKTIQEINERIKEGNARVVTAEEMPQIVAELGEEGALAEVDVV
                     TTGTFGAMCSSGCFFNFGHADPPIRMEKVWLNDVEAYAGIAAVDAYLGATEKSTTREE
                     NYGGAHVLEDLAAGRSVELRAISRGTDCYPRRTITTEILLENCNQAIMVNPRNGYQRY
                     NAAGNSGDRVLHTYMGMLLPSLGNITYSGAGVLNPLANDPHLRVIGQGVPCFLGGAEG
                     MVVGEGTQASPATGFGTLMVTGDLKKMKTEYLRAATMTGYGVTLYVGLGIPIPVLDIE
                     TVRSTAVRDEDIWVDIIDYSVPSRSRPSLGRVSYAMLRSGRVEIGGEEIRTSSLSSFR
                     RARMVAAELKGWVESGRMTLALPTRPLDPGRKAEPMKETVQGPRVLQIMERRVATIGE
                     DEPIRDAAAKLLKGETNHLPVVNGNGVLVGIVTTYDISKAVVNPGKGNFVRDIMKRKV
                     ITTTPEESVDIAIRKLEKYNISALPVVDREMHVVGILTAMDLGKLFGGRWLK"
     gene            20193..20921
                     /locus_tag="PK679_04090"
     CDS             20193..20921
                     /locus_tag="PK679_04090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HPC55169.1"
                     /translation="MDISQFLALMEDIAPPGLAEEWDLGRIGLVVEGDRDIERISCAL
                     DATPAVLREAVGSGSDMLVVHHTPLWTPVTSVAGALASLLRPVLSSGMHIYVIHSNFD
                     HAPGGINDALAKLLRMENIQPLSLGVVGDCPLSPLDIAGILDCPVVTWGNPDLPGRLA
                     LAGGSAFSPDLISEAACKGARAFLSADLKHSVARESPLPLLEATHYALESPGMRALAE
                     RMGWTYIDDPPVVRTWNPTSSGND"
     gene            20891..21223
                     /locus_tag="PK679_04095"
     CDS             20891..21223
                     /locus_tag="PK679_04095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HPC55170.1"
                     /translation="MEPDEFWERLKEERCLTPRLREELLRIYGERGKKALEAIDSGRV
                     MQYRDFVVVAGKSDQYIVEDDFCTCHDHLYRRGLCWHLLAVRLAATAGGFRQVAEWYQ
                     EKWIQKRG"
     gene            21276..24017
                     /gene="alaS"
                     /locus_tag="PK679_04100"
     CDS             21276..24017
                     /gene="alaS"
                     /locus_tag="PK679_04100"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HPC55171.1"
                     /translation="MLEEEYQLEYFKTQGLTRKICSRCGAAFWTRDPDTLTCGDAPCE
                     TYRFIGAPVFRCHTVDEMREAFLSFFEQNGHTRIARYPVAARWRDDIYLTIASIADFQ
                     PWVTSGIVPPPANPLTISQPCIRLNDLDSVGRSGRHLTLFEMMAHHAFNREGEEIYWK
                     ERTVELCEKFLSSIGADLSRVTYKEHPWIGGGNAGPSLEVLIGGLEVATLVFMNLGRT
                     KTGKPGIDLGGETYYPMSNYIVDTGYGLERFVWASRGSPTIYDAVFPEMVSRVMEAAG
                     LAHALEDKEYTKILSLNARFAGVMDISGTNLWQLRKKVATAINVPIERLDRMIAPVEK
                     VYAIVDHTRCLAYMLGDCIVPSNVREGYLVRLVLRRTLRMMKELGIKESLADLIEEQM
                     KIVGTGAFEQDICIVREIVEREVEKSNATLERGTKIVQRIARTYKSRRERVPLREVIT
                     LYDSHGIPPEIIREVATAEGAVVELPDNFYSLIAEMHSESEPEEEEDPFARYSERISM
                     LPATRRLYYEQPSDMEFDAMVIDFFDGYAVMDQTLFYPEGGGQPSDTGMLISAENMVK
                     VDDVRKVGDVILHHVTGGVLRRGDHVKGIIDEERRWSLMRHHTATHILLHASKEVLGA
                     HIHQAGAQKGPESSRLDIRHYKHITPDELRKIEIAANRMVMADLPIDVKYLDRTKAEQ
                     MYGFSLYQGGVPPGKEIRVVRVAGDVEACAGTHCRSTGDVGFIKVIRVEHIQDGIERL
                     EFAAGLAAVEYVHRIEKILSGSAEILSVQNEYLPATVNRFFSEWKAQKKEIERLRQRI
                     AELEKKSLAAEVVGNTPVLVRRIDLSGKELATIGHEIAARGGVALLASGSDQATVLLM
                     SGSDRVNAGELIKDVCAVLGGKGGGSPAMARGGGPAVEKIEEALAIGKQKIIASLGT"
     gene            24032..24691
                     /locus_tag="PK679_04105"
     CDS             24032..24691
                     /locus_tag="PK679_04105"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC55172.1"
                     /translation="MESSSEDTGSGQPDPNAPDGEVVILVPGDERSQKIAKAISSQAA
                     GDILHALERGPRTAGDLASALAMPMGTVKYHIENLLEAGLIEVRDTKYSVKGRQVKVY
                     GLRNQLLIMAPRVRNIRSILLRYAALFSVVTLSSLAMYAVLAASRLSAAGFGEGDRAN
                     FQAEKTAGILAAPTPAPTPEPYPFSQALPADIALAFFFGGVLVLIILLLYEVSVWRRM
                     K"
     gene            complement(24710..25516)
                     /locus_tag="PK679_04110"
     CDS             complement(24710..25516)
                     /locus_tag="PK679_04110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55173.1"
                     /translation="MKSAVFSLLCILCLVQGVLAYELTIQAPKEVRAGVPVEVTGNTT
                     FPVGTEFDLVLYRIQTTMPEPVFEKTVVVSDSKSFEITFPTMGLSPGEYKVEVRFRSD
                     PGSKLSSGSVTTRMLTITDRSGEIVITSAKDQVIGEALRIEGYVPRGGVVTLTMKVTG
                     PQGAVIPPEDIRTTTVLGKDDGFFSRTIPVSEKGNYYVDFSDVKGYITTVKFTVSEPG
                     GTAVPSTEITHGTTTESPSPTATAVSPFPVAGAIAGLIIIALVFCVHRKK"
     gene            25672..26100
                     /locus_tag="PK679_04115"
     CDS             25672..26100
                     /locus_tag="PK679_04115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55174.1"
                     /translation="MESITLKVQERAFPSRGRARINEVHLKTLGISEGDSVEVSAGSD
                     KKPVVVTVFADKLVEEGYIRLSPEDIAQAGAMSGAVVTVTRVPPVSERVKKTADKAKE
                     SVAKDVKKAKEVISKKSSEAKESMEKGVESAKKSLHEKDL"
     gene            26119..26502
                     /locus_tag="PK679_04120"
     CDS             26119..26502
                     /locus_tag="PK679_04120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55175.1"
                     /translation="MTDMWVIFEGILPYLLVFIGLIIVYFIIREFRLMYSRTRLAQLE
                     LEREKINLLKADLEQRGRPFYRVSPQDLEELKRLDEENVELETDIFARHTAVEKRLKR
                     LESRVALTKLDRMIEKIKREEERLG"
     gene            26499..26816
                     /locus_tag="PK679_04125"
     CDS             26499..26816
                     /locus_tag="PK679_04125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55176.1"
                     /translation="MRQVTEYGTPGRTTEKYPLLESIKEIPAVIDEHLPTMDKGLDEY
                     FNRHFPAIISEWGLVTSIHLKNLERRLDRVHRQIDVLEKNQKALEKRAAALDKELRGL
                     EGR"
     gene            26813..27034
                     /locus_tag="PK679_04130"
     CDS             26813..27034
                     /locus_tag="PK679_04130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55177.1"
                     /translation="MRRPDYLGSYVDRRMKYLIEEWDLATRRDLGDLVSRLSSLEEES
                     RLCAGFEATASAKLTELEKRLEYIRGRRK"
     gene            27031..27369
                     /locus_tag="PK679_04135"
     CDS             27031..27369
                     /locus_tag="PK679_04135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55178.1"
                     /translation="MTIIEGLLVLILIAVIAFTLYYYFRGSTGRLDISRPLESRIDEY
                     LDRKFDMLIEEWSLIRRSQAEQFRDEKMPLLAKDEERMAALKAFEKDFGEELTRLEER
                     IEALEKQIPR"
     gene            27431..27649
                     /locus_tag="PK679_04140"
     CDS             27431..27649
                     /locus_tag="PK679_04140"
                     /inference="COORDINATES: protein motif:HMM:NF025801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55179.1"
                     /translation="MRRQGDSPTRDPASFSRYSCDLCNDTFPKKDLRQCALCGRWACA
                     SCWTEKYYACKACNGIITLHLTTDKPGE"
     gene            complement(27988..28542)
                     /locus_tag="PK679_04145"
     CDS             complement(27988..28542)
                     /locus_tag="PK679_04145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55180.1"
                     /translation="MFPWLRSHVRVLVELSRAILFLFTFVLVVPLLIGAVLGIPESRI
                     LPLIASAFILQGAAPPLGHPLGLADPVIIVLMASFAVGVVTCILEVCDALSLTSERVA
                     RWIRKVGERMEKHPSIRSYGAISCIFIAWIPGIGLYGTPVIAWILGWQKVPTVIFTTA
                     GFVIASGLVLTVTLVAENIHHVFF"
     gene            complement(28715..29323)
                     /gene="hisH"
                     /locus_tag="PK679_04150"
     CDS             complement(28715..29323)
                     /gene="hisH"
                     /locus_tag="PK679_04150"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HPC55181.1"
                     /translation="MKKITIVDYGLGNLRSVSRGLEKAGGRPVITTDPADVASADGIV
                     LPGVGAFRDGMEQLGELRIVILEASRSVPLLGICLGMQMMLEWSEEQGLHRGLALVPG
                     TVRRFPRVSGFKVPHMGWNSLSSVRQDNPLFEGIRPGDYMYFVHSYYADTKDRYTLAQ
                     TEYILPFASSIWDERYVFGVQFHPEKSGSRGLCLLKNFLGLL"
     gene            complement(29301..30713)
                     /locus_tag="PK679_04155"
     CDS             complement(29301..30713)
                     /locus_tag="PK679_04155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HPC55182.1"
                     /translation="MPSPLSFRGMLWWCDTCHTPVLSRGCSRCGGVTRRVMLTPPGDP
                     RPAFPADVDLVNKVYSDHFGSPLIPDGHLALLNKVPDTDRMEEVIVGGGVVGAIRYIP
                     EEGRWEAIPRKEAFGLSAPPRKWVVADAGAAAAIRDRSASLLAPGLVTIEPSVRKGDE
                     VFVLDEKGECIAVGRARVDADAAGSMERGLVVRTRRTFASVCVPGKATWDDAVAANAG
                     PLSEHEEEAIGFIRNVGQGHEGFSQNVSYSGGKDSLVTLILVTKALGKVPLLFADTGL
                     EFPETYDNVREVAARYGLPVTVAQGSEAFWEAFSTRGPPARDFRWCCRAAKLTPVDRV
                     IRNTWGECLSFIGQRKFESSRRMASHRVWRNPHIPAQVSAAPIHHWTALHVWLYLFRE
                     KAPYNRLYEQGVDRIGCFMCPSSDLAVIRHVISRYPALWETWDTRLKEWQKANSLPDS
                     WVEDAGWRIRGGSGEEDYNC"
     gene            31051..31578
                     /locus_tag="PK679_04160"
     CDS             31051..31578
                     /locus_tag="PK679_04160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter subunit E"
                     /protein_id="HPC55183.1"
                     /translation="MIAYLVTFIMAFLLYLVFSAGSGTLWLWSPSELLAGFLLSLLTA
                     AVAGKVLCRGKDYRMANPVRLLILPVYILGPFFIEVTRANLDVAYRVITGKIRPGIIR
                     VPSGMKTDFGAFLLANSITLTPGTITVDISEETNDLFVHNINVPAGWETRDTVEAREL
                     FGLANIPAWIRRIAE"
     gene            31575..31832
                     /locus_tag="PK679_04165"
     CDS             31575..31832
                     /locus_tag="PK679_04165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015075 - monoatomic ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation/H+ antiporter complex subunit
                     F"
                     /protein_id="HPC55184.1"
                     /translation="MTAPFDIAVFILLVLVCLALVRLVLGPTIADRAVAVDTVNTLVV
                     AALIVLGVVYQQIIFIDVAIVYALLSFVSTLYVAKYIGGEL"
     gene            31829..32185
                     /gene="mnhG"
                     /locus_tag="PK679_04170"
     CDS             31829..32185
                     /gene="mnhG"
                     /locus_tag="PK679_04170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051139 - metal cation:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation/H(+) antiporter subunit G"
                     /protein_id="HPC55185.1"
                     /translation="MIADVLVVACLVIGTAFNCLGIIGLLRFPDVYTRMHATTKMTTF
                     GSVFTALSVIIYGAAQFIGTGDGQYVTLAVHTLLAALALAVTNAIGSHAIARGAHRSG
                     IKPAQAVVDRLGEVPP"
     gene            32182..32436
                     /locus_tag="PK679_04175"
     CDS             32182..32436
                     /locus_tag="PK679_04175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4040 domain-containing protein"
                     /protein_id="HPC55186.1"
                     /translation="MIELLIQVAVIGGLIASAILVYSFRDLLAAALAGGFFSFLVSLE
                     FYILQAPDVAISQAAIGAGLTTAIFIIAIRSTTRFEEETP"
     gene            32433..32717
                     /locus_tag="PK679_04180"
     CDS             32433..32717
                     /locus_tag="PK679_04180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55187.1"
                     /translation="MKKVLVAAIFLVWAAGLCAIPLFLSFGNPAATDMDTYFIRTGQA
                     AAAANNIVTSVVFDFRGFDTLGESVVLFTAVTGVALMFRARKEGEDHEDE"
     gene            32704..33171
                     /locus_tag="PK679_04185"
     CDS             32704..33171
                     /locus_tag="PK679_04185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MnhB domain-containing protein"
                     /protein_id="HPC55188.1"
                     /translation="MRMSKIVRTGACILYPLITIFGLYVVVHGHLTPGGGFQGGAVIA
                     TAAALVLVAFSHADIAGMVRKTVFSAQESLGLLLFIGAGILGLLAGAPFFANILANSG
                     LLFGLAVPPGSNPGDLNTAGVIPIMNIAVGVEVWGGLAIILMYLFSATGGEGA"
     gene            33168..33521
                     /locus_tag="PK679_04190"
     CDS             33168..33521
                     /locus_tag="PK679_04190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter subunit C"
                     /protein_id="HPC55189.1"
                     /translation="MTPVLYNLPFVAVVVLTIIGLATIVLKRNLIKIFLGITILESAV
                     NLFLVSLGYREGGIAPIYTNAPDRLMVLPTPQALTLTSIVIGVATTALLLSFAIVIWK
                     KYGSIEIGFLRRLKE"
     gene            33518..35095
                     /locus_tag="PK679_04195"
     CDS             33518..35095
                     /locus_tag="PK679_04195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HPC55190.1"
                     /translation="MIPPFVIENSPALMVIVPFVAAFIAPFSGRVAPALRALVVGGAM
                     AITSAITLLLASDVYAHGTRLYVFGAQAATLAVPPDSGGIPVRIMFTVDPMSALMLVI
                     TAISAFAVVLYSLTSERHHSGLGSYYTLFLLMVTGILGMVSTGDIFNFFVFLEILSIA
                     SAGLIAFRIDGGVAVEAAIKYFVLSTIGALAILFAIGIYYGEYNALNMALIAQRMQFT
                     LLDQLALVLIIAALAMKCGAVPMHFWTPDAYSMAPSSITALLVVASQASLYGLFRTVF
                     SLYNITLNAACVGWLIIILGVLSMVVGVTMAIPQKNVKRLMAYHAISQTGYMLLGVGV
                     GLAVLGNQPLLDAFGYMAMEGGIFHIINHAMYKGLLFLTAGAIFFRIGTYDLNKMGGL
                     GHSMKWTMIFFIIGALAIAGIPPFNGFASKLMIYESVFAFNPVLSVIAMVVSILTLAS
                     FVKVFHSIFMGPVLPEYKDVREVPRPMLAGMGILALVVILFGIFPSLVVETLVAPAAH
                     ALADQGMYIAAVIGGGV"
     gene            35100..35447
                     /locus_tag="PK679_04200"
     CDS             35100..35447
                     /locus_tag="PK679_04200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HPC55191.1"
                     /translation="MDMLFTLDTGAGFWNPVLWILGAAVAGVIALILYSLGEKGYRKG
                     TAQEDPFISGNPEPEKGLVHVRSGNLYWGFLDAMNGYYRRLVPLHTGDLHDYVLWYMG
                     MTALFLVVVVVFR"
     gene            35444..35878
                     /locus_tag="PK679_04205"
     CDS             35444..35878
                     /locus_tag="PK679_04205"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990204 - oxidoreductase complex
                     [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B family
                     protein"
                     /protein_id="HPC55192.1"
                     /translation="MKLNALFNRSLWVYHFNSGSCNGCEIEIVATLTPRYDPERFGIR
                     LVGSPRHADVMLVTGPVVHRMKDRLLRVYQQIPDPKIVMCIGTCGISGGVFYESYNLD
                     GPVDEVIPVDVYVPGCPPRPEAIIHGVVKALEKLERLQGVEA"
     gene            35875..36522
                     /locus_tag="PK679_04210"
     CDS             35875..36522
                     /locus_tag="PK679_04210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HPC55193.1"
                     /translation="MKEGTLTPEEVMAHLTSRLSGGIRDTSIRKWEQGRKKVPHYTLW
                     VDLERDFLKPAIRALMEIQFPHLSVIAGADLGDAIRLLYIFSVQYGSPKSEYMVTFAI
                     ALPKSDLTVPTISDLIPGAVFSEREKQEFFGIRVTGIPDSRRLFLPEDFPEGVFPWRK
                     DETGVPEGMVRELWESKRPKDRPAPPVKEKGPGTAGGETPAASAPAGGSAKEGER"
     gene            36519..37748
                     /locus_tag="PK679_04215"
     CDS             36519..37748
                     /locus_tag="PK679_04215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent hydrogenase large subunit"
                     /protein_id="HPC55194.1"
                     /translation="MSGESKKAPYRVPIGPNHPALKEPVMFTFELEGEVVRDVDFAPG
                     QTHRGIEWMGMRRNPVQIVHLTDRICGICGVVHSLSFSLAVEQIAGIEVPERADYIRT
                     IVHEFERIQSHLLWAGVAAHELGFDSLLHLTWRVREEAMDVIENLTGNRVNYGIVQVG
                     GVRRDIVPEQHAIIEKCLATYEGLLDTLLSFFLDDRTIRMRCRDVGVLSRKDALELCT
                     VGPTARASGVNVDLRQDYPYAAYGDLDVKAVLPDRYLGETHGDVYDRIVVRLLEVGQS
                     CQIIRQCLSEMPAGPITAEEKLVKLLATCKKATGEGIGRVEAPRGECLHYVRMEGKDS
                     PASWKVKASSYSNLMSWIPMLRGSQIADIPIIVASIDPCLSCTDRVAIVQDSRRSILS
                     KDDLHRLSVEKTRRLQG"
     gene            37745..38764
                     /locus_tag="PK679_04220"
     CDS             37745..38764
                     /locus_tag="PK679_04220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="HPC55195.1"
                     /translation="MTPAEIALLAAWCAALSLFALAGGLLLSGIDRKLAAHMQARIGP
                     PIRQPFIDTVKLLQKDTVVPANAIPWLFNAAPVVALVSSVLVLFYIPVGSTMPVLGAY
                     GDLVLVMYLLTVPALALVAGGFASGSPYATVGAQREMVTMIAYEFPLAIVVIGVAWRL
                     GAAGISHPFALQSIAANPVWSVTGPLGLAGVFILLVVLAAITPAELSRIPFDTQEAET
                     ELAGGLLVEYSGRNLAMFSLAQAAKTLVLAAIIVAVFFPWTLSSFLAMPPVVALAADL
                     LFFLLKAVLVLFFAVTLVRVAMARFRINELVSFYWVYLSVIGLAGLLLLMADVIAGPL
                     AGVGI"
     gene            38761..39165
                     /locus_tag="PK679_04225"
     CDS             38761..39165
                     /locus_tag="PK679_04225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HPC55196.1"
                     /translation="MRALPLVPELVRQLFRRPATNRFPAKYLPPSIRAFLRDVQAGRA
                     AVNPPVPTPPRFRGKIAYDRDSCIGCTLCVKVCPAHAIEFIPDIKKIRVWVDQCIFCS
                     QCTSICPKSCLSMTDAFLLAGEDRYAEDLIVE"
     gene            complement(39405..39848)
                     /gene="hycI"
                     /locus_tag="PK679_04230"
     CDS             complement(39405..39848)
                     /gene="hycI"
                     /locus_tag="PK679_04230"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HPC55197.1"
                     /translation="MVNILLGVGNPLRRDDGVGNYVAAGFRRQGWMSLDCGTVPENFT
                     GIVRREHPGLLVIVDAAEMGRSPGEFCVVPKERLRDVSFGTHQLPLDVIVDYLAHSAG
                     RIVIIGIQPLVVETGEGLSPPVREGADRLIGYLERGEPDRIPVFR"
     gene            complement(39880..40437)
                     /locus_tag="PK679_04235"
     CDS             complement(39880..40437)
                     /locus_tag="PK679_04235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE thiosulfate transporter family
                     protein"
                     /protein_id="HPC55198.1"
                     /translation="MPFEGIRQNKSLQALLGLVFGTVFGFLLQKGGVTLYDVIIGQLL
                     LTDFTVVKVMLSAILVGMVGVHAMKAAGLVRLHVRAGSVGSTVIGGLIFGVGFAVLGY
                     CPGTAAGALGSGALDAAVGMAGIVIGAGIFARLYPVLERSVLNRGKFPAETIPQLLGV
                     SPMPVACAVAIMILVILALFATMGL"
     gene            complement(40450..40974)
                     /locus_tag="PK679_04240"
     CDS             complement(40450..40974)
                     /locus_tag="PK679_04240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE thiosulfate transporter family
                     protein"
                     /protein_id="HPC55199.1"
                     /translation="MSDWLLSATWSPYVVGAGIGILIWMTFLFSDRPLGASTAYAKTA
                     GMIEKAVSRKNVASMPYYRQVTPEADWQWTIIIGVIAGGFISAYTAGTFALSAVPPLF
                     AETFGADTLFRFAVALAGGIIMGIGARWAGGCTSGHGISGTLQLSLASWVAVICFFAG
                     GILAAGLLFGFRFL"
     gene            complement(41026..42393)
                     /locus_tag="PK679_04245"
     CDS             complement(41026..42393)
                     /locus_tag="PK679_04245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC55200.1"
                     /translation="MIIRQFFVPGIAHSSYIVAGNRACAVIDPSRDTARYITFARSMG
                     LSITHILETHLHADFVSGHLDLANETGAGIYAPRAGHCSFPHEGVVEGDEIQIEDMTF
                     RVIETAGHTPEHVCYVATDLSRGKTPVALFSGDTLFVGDVGRPDLFPGRAEELATALF
                     GNLQAKILTLPDECELYPAHGMGSLCGRAMAAKRTSTIGYERKYNYALRIRDREEFVR
                     ALTSGMPAAPDHFSRCSEINRKGPALMRNLPEPLPLGPEPFSQRARGGGAVLLDVRSY
                     PAFSGLHIPGSWHIDLSGNFATQAGWILPPGQDICLVAENREQAMEAALQLRRVGFDS
                     IAGYLDGGMLPWSAAGLPVDRVPVIAPADAHALLEKGDAVLVDVRSREERTAASVKGS
                     VHIPWHDLRSRYVELDPGMHTIVMCRGGQRASIAASILKMKGFKTVSNLAGGFSAYQK
                     AGFVS"
     gene            complement(42400..44178)
                     /locus_tag="PK679_04250"
     CDS             complement(42400..44178)
                     /locus_tag="PK679_04250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HPC55201.1"
                     /translation="MDTQILLVSAIVVGTLVLFASDLIRVDLVAILACLAVAWSGLVT
                     PQEAISGFSSNAVVAMAAVMVLGTGLERAGVTSRLAAFIVRYAGAAEQRVVAATSLTV
                     GLLSSVIHNVGAAAIFLPAAGRIARRTGIPVSRLMMPIGFAAILGGTVTMIGSGPLIV
                     LNDLLRQGGAEPFSLFAVTPIGIVLLLAGVALFSLAGHRVIPGTGGEVPRPSVPEIWN
                     INQPILTCRISESSPLSGKTREEVFSGNPHGLFLLAIRDGDDIQVAPSRWFRFEPGQE
                     LAILGPKEGFEQFARKTGCIPAGETGSFAEILTGGGYGFAELVVRPRASIIGKTPREI
                     MFRKTFAIEPIVHVRGETETRADFSDMPLAAGDIIVAFGSWENLRVLARHTDLQLISQ
                     PEGDPVHYRKGFLAVLIFASSLALTLTGVPLSLALLTGALAMVLSRVLGPADVYRAID
                     WKTIVLIGGLIPLGIAVEKTGAAALLAGSLAGVLSGTHPLVVMLVVAAIATCLSLVIS
                     NVAATILLVPLVMVTGQDMGVDPRALALLVAVCAQNSFILPTHQVNALLMGPGGYRPW
                     DYIRAGSIMSVMFIAIAVTLMYLLVL"
     gene            complement(44287..44967)
                     /locus_tag="PK679_04255"
     CDS             complement(44287..44967)
                     /locus_tag="PK679_04255"
                     /inference="COORDINATES: protein motif:HMM:NF015000.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HPC55202.1"
                     /translation="MEIIGHRGAAAAAPENTLAAIRIGMECADYVEVDVRLSRDHVPV
                     LMHDPTVDRTTNGNGRVAEFSAADLRLLDAGKGEPVPTLEEVCLLIGGKTGLCVEIKE
                     PGSELEVCEVLDRVAGGPLLVVSFHRASLAMVHDVMPDIPLGLIHTQPVPPTPRKSED
                     PPFRVYLPKFDTLTREAVEEVHARGMRVIPWTLGSTAEWDRARGMGVDGFATDDPCKA
                     RRWRDTVQ"
     gene            45114..45797
                     /locus_tag="PK679_04260"
     CDS             45114..45797
                     /locus_tag="PK679_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HPC55203.1"
                     /translation="MDVPLKTSLFEICPAKGVPLSERLIRIAIPFVIGGFYILLCFLF
                     LPSDSALLLGGLMLGYLVPPAGKESIVPLGIALGFPWWLIAFSIGLMDVLAGIFMALN
                     CDVAVKIPLLGRWIRRFLEKGNDFVRKRPWLEKFYFSGVVLFVMFPLQGSGGIGGSLV
                     GWMIGLSPGRTLLAITIGAFLGCTLVAIGSQAIRDLLLSNPVAGILALVAVIATLVIS
                     YSFYRWKIR"
     gene            45853..46413
                     /locus_tag="PK679_04265"
     CDS             45853..46413
                     /locus_tag="PK679_04265"
                     /inference="COORDINATES: protein motif:HMM:NF021420.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2121 domain-containing protein"
                     /protein_id="HPC55204.1"
                     /translation="MSLVIAFCGRDRSFMAGDRREIVFRGDDLRTRTLEDELYSGRIR
                     SRDALHERARELGIDLWIHDDRCKAWEEDGILIGQVNERDGLSTRSRRLCVSCGNYVI
                     TEVLEGIKREVTRGCASRFIVLGNKTTQEIAHRCIRSHWSDTGGTPADALRIIILAME
                     EAASLTPSVSGTYTLVQTTAKTVLPP"
     gene            46578..46859
                     /locus_tag="PK679_04270"
     CDS             46578..46859
                     /locus_tag="PK679_04270"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55205.1"
                     /translation="MNPKVRLIIEETFPKLIERHIRTRPAVEATQKSLDSYRKMGYAA
                     VRNLSPEERDLNEKALDTAYAASMQQLHDFHAREKSHSGTMEGTEKETI"
     gene            47010..48335
                     /locus_tag="PK679_04275"
     CDS             47010..48335
                     /locus_tag="PK679_04275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HPC55206.1"
                     /translation="MRTDCIIYTILGLLLIALLLGAGCTQTPSATGPSEIKIGVVASM
                     TGPASTTGKDIWQSAELAANEINAKGGVPVRELGRSLPVRLIQGDDESTREGGMKAVT
                     KLITQDEVNVLVGGYSSAVVSAHQSIVADNKVPYIISGASSSAVSRRTDLDTSYMFFH
                     RPNTDDSAEASIQFLTDVFRPAINEKFGFSNDRKLRVAVIYQDSPFGKGQLDAVKALI
                     PAKNLPIEIVAEEPFKMGESDFRTVLTSVRAKNPDVIYAVTFLNELVPMTQQARRDVG
                     LNTVIMAIENNDDPDYYSGVGVYGDGMIMESRFSPYAVPAGSTEAATRKFLSDFDKKY
                     GGFAGMMGAATYESVYVAAAAIEQAGSLDRAKIRDALATIRVPQMMEIMKNGTISFSP
                     EFRESKFELYVVQLAMDQKSGEPRPVIVWPESLKAGEFSIPDWYTPGSP"
     gene            48370..49251
                     /locus_tag="PK679_04280"
     CDS             48370..49251
                     /locus_tag="PK679_04280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HPC55207.1"
                     /translation="MDGGIAVLGQVAFWGLYSGCIYILLATGLNLIFGVMKVVNFAHG
                     EFLMLGTYITFFFFVISGFNPYLLLFLSIPILIGAGIIVERLCFRPILGTGKLNEIFI
                     SLGLIYIFQNGVAMVFTDEWRSMKSPFADLTIGIGPIQLPLDYIIIVVITAIILVGLS
                     VFLDRTTTGKAIRASSQNRKGAMLMGINVERMDMLTFGIGAGLAGAAGTLWAVSGQVF
                     NPYMGSVPAIKGFAIIILGGLGSIPGAIIGGLAIGMVENFTAFFLGGSWKDAISFILL
                     IVVLLVRPTGLFGEAGE"
     gene            49248..50213
                     /locus_tag="PK679_04285"
     CDS             49248..50213
                     /locus_tag="PK679_04285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HPC55208.1"
                     /translation="MNLAQVRTPKNLLAAAILILALALPFLVGQNLYLLTVLVLMLIF
                     IIYSSAWNFLTFSGQGSLGHAAFLGLGGYAASLATVRLGLPPLLTLVLGGLFSAFIGI
                     LIGITCVRLREWFLAMVTFGFAVIIQTLVVSQLAPVTGGWDGFAVQKIVPTTIPGYLV
                     LEYYVVFLIAVLVLVLFYLLLRSRIGLALAAIRENETEARAAGINPVPFKLFAFGLSA
                     FVSGIAGGLEIFHFGYITPEIFGIDLSFWPIIYSITGGLGTLAGPVIGTIVVTLLWDG
                     LNVLGLTYGRFIIIGVLLVLIIIFLPRGLVSLPEEIGKKWGRKGK"
     gene            complement(50247..50939)
                     /locus_tag="PK679_04290"
     CDS             complement(50247..50939)
                     /locus_tag="PK679_04290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55209.1"
                     /translation="MLHIEDLNVSYSYLQVLWDVSLHVDRGEVVTLIGSNGAGKTTLV
                     SALFGLVPAIGGRIEFEGENISGMAPFEIVRRGLSLVPEKRELFPRMTVRENLELGAF
                     ATGRKGDPDRVFELFPHLAERQDQDAGTLSGGEQQMLAIARCLMANPRMIVLDEPSLG
                     LSPKLVHTVLEAVERLNSEGITILLVEQNVRRALEISHRAYVIEAGRITRSGRSSELL
                     HDEQIREAYLGL"
     gene            complement(50961..51716)
                     /locus_tag="PK679_04295"
     CDS             complement(50961..51716)
                     /locus_tag="PK679_04295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55210.1"
                     /translation="MLFVSRVHGMLTVRGVTKSFGGLVAVNQVSLTLNEGEILGLVGP
                     NGAGKTTLLNLISGIYRPDAGGIVFCGEDITRLSLDAVCKKGISKTFQHPRSFPALTA
                     RQGVMIGALYGNGRRPTVREASREAEECLRMVGFPEDKIDSPITNLNTFELRRTQLAR
                     ALASHPKVLLLDELTTGLTPSEGKEAVSLIRKLRDEGMTILMIEHVMRIIMGVSDRIV
                     VLDHGEKIAEGEPAEIVTNEKVIDSYLGERYHF"
     gene            51768..53090
                     /locus_tag="PK679_04300"
     CDS             51768..53090
                     /locus_tag="PK679_04300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HPC55211.1"
                     /translation="MVRPVYIGAVLLLVLALMAGCTEQKAQTQETLKIGVVASMTGAA
                     STTGKDIWQSAVIAAEEINARGGVYIKDINARVPITLIQGDDESSREGGQKAVSRLIT
                     QDGVDILVGGFSSAVVSAHQATVSEYKVPYIITGASTPTITQRTDIDTGTMFHYCPTT
                     DDYGEQTTLFAYEVIRKAINEKFGYPDSRPLRMALIIQDSPYGKGVQKAVKETIEKKN
                     LSIVIVAEETYKMGETDFRTQLTSIKAAQPDVVYPAAFLNEQIPMVTQARRDVGLDTI
                     FLAVECNDDPDYYAGLGKYGEYSVIETRFSPYAVPKGPVADDMVAFRENFHKRWGSYP
                     GMMGASTYEGIYIAAHAVEKAGTRDKAAVTRALATLEMPQMVEAMKDGVIKFSRDYRE
                     AKFDLFMEQLVWNETAGELRPRIVWPDHMKEADFVLPDWYVPGPAAAP"
     gene            complement(53120..54874)
                     /locus_tag="PK679_04305"
     CDS             complement(53120..54874)
                     /locus_tag="PK679_04305"
                     /inference="COORDINATES: protein motif:HMM:NF017078.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHASE4 domain-containing protein"
                     /protein_id="HPC55212.1"
                     /translation="MKIRSSVTLTFIIVIVISLLIVAVATQLALYPAVKDIEKREAEN
                     AVLKVIRIIEYDLGTLGGTCEDWGKWDDTYYFAKGENEGYPAENLVNETFLALRLDLM
                     LFYDTNGTLVYGKGFDYSRQVALSIPDDLSHIPAIPEPDSNNSGDDVPPLSGVISTSR
                     GPLLASIGPILPNDRTGPAAGYLLIGRYLDGDETTHYASLAMANLTFREAGPADEPGF
                     AMSPGFHEAIPITLRLPATGEYLVAESTINDISGSPAFITSITLERTVFQIAKNSIIL
                     FFVIVVLAGGAIGITAIRFLDRKVLSRVSLLEKTVREITEQKDFKGRTALSGDDEISS
                     LSTSIDRMLDALDEHVAAETAAKDDARLANAKLTLLSRITRHDVLNQVTIVRGFADLL
                     SESIPQDSADIEYLKKIKSAAKTIEHQLAFMREYELEASPSSVGWIDVRKLFLEVAMG
                     MGLFGVKAEVLFDNLFIYSDRLLAKIFSTLIDNSVSHGERVDRITLSFYESGDKGVLV
                     YEDNGIGIPPDQKELIFEQGVGRNLGIGLFLARGILSVYGMEIRETGEYGKGARFEIL
                     VPRNKYRKTEGGNPPPSP"
     gene            complement(54992..56185)
                     /locus_tag="PK679_04310"
     CDS             complement(54992..56185)
                     /locus_tag="PK679_04310"
                     /inference="COORDINATES: protein motif:HMM:NF014713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="HPC55213.1"
                     /translation="MAGNKKRRETRFFILLFATLLILACIFPVTAREETDQGFPSPSA
                     GEEQPALPVSPDHRFTDKGPVIVMFYNTNCGDCMRTLPFVQQYVSEHPELETHLLNIK
                     ENFDYWKLFSVYKDAYNTGPIPVPSIFVGDRVLTGYDEITGSLGEVVKEQSHGPAPGT
                     TPGFPSLENISAQEMTIPLVIVAGLADGINPCAFSVLIILLFTLSVAGSRKKMVTVGA
                     CFIGTVFVFYFLSGLGIFYLIQLAEISRAIGIIAAGIAFILGAISLFEGVFDREKPTL
                     AIPGSKKGIIGDYIQKASVPASIILGVLVGMFELPCTGGIYLAILSLISDKMTMAEGI
                     PLLLVYNVFFVLPLVLILCAVVFGLPLERVDRWRQEHRRAVRIIMGLVLLGLGVLLIR
                     SFLAW"
     gene            complement(56365..>56559)
                     /locus_tag="PK679_04315"
     CDS             complement(56365..>56559)
                     /locus_tag="PK679_04315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HPC55214.1"
                     /translation="ACSTCWETCPEVFEENGDDSFSQIREKYRAGGSISEGEVPDSLK
                     GCVGEAAALCPVRIISVTEE"
BASE COUNT        11872 a        16656 c        15930 g        12101 t
ORIGIN      
        1 tcgcactctg gatcgtcatc atcgcgacac ttgcctattc aaccttcctt gctccttctc
       61 cggcgatatc cacccagttc aacctttccg tttcaggaaa tgaagcattc atcacccaca
      121 cggggggaga cccgctcccc tgcgacagcg tcgccattct cctcaacgac agggaagtcc
      181 ccttcccgaa agacagcatc gagtgcccct ggtcgatcgg cgagaccgtt tccatcagcc
      241 tgccgcggtc aggttcaccc gtgaccatca ggatcgtctc gtccgcttcc ccgaagggta
      301 gccgggaact cttctctgcc gagatccctg caatgactcc tctggccacg ccgtcaccac
      361 cacccacccc cgccacaccg ggcacaacgc cggcaacggt ggttcccacc atgacaccga
      421 cacctgcccc gacactcatc ccgatcgaca cgctcggggc acctgttgct gcctttacag
      481 cggaaccccg cgagggcccc gttcccctga ctgtcaggtt caccgacacg tcccgcggga
      541 tacccggaga atggtcgtgg acgttcggtg acggggagac atccaccatc cagaaccctg
      601 tccacaccta cacgaaaaca ggatcgtacc aggtggggct caccgtcagg aacgcgttcg
      661 gcgggcacac gaggatcagc caggggttca ttacggtcac gcctgcagag aaccgcgacg
      721 tctacctgga ggcgcagaga gatgcccgcg tgcctgcagg cgggtttttg gagttcactg
      781 tcagggaggg cggatcccgg gtgaagatcg gcggcaccgt catcgatctt cctcccggtg
      841 cacgtgtccg cctcaccctc ccggccggcg ggaaaggcaa ggtctccatc cgttcgggaa
      901 agatccttgg attctccttt gaaaacaccg tcctctccat cgacggtgaa gtccgggggc
      961 agggagaggt cagggagatc tccgtgcagg gatacgatga cctcgtctcg agcctcgtcc
     1021 tcgtcgtttc gcagggtccc ggaacggtcc gcctcctgga atcggggatc ccggtcgacc
     1081 tcccctcggc agactctccc ctcctcctga tctccgcacg ccctgacccg gcaggaatcc
     1141 tgaacatcga ctgtttccgg ccggattcgg cattcttcca gggtgcggtg tcaggatatt
     1201 cctttggacc ggtatagggc ctttcgtgta cttcctgcca atcataccct gcccgtccgg
     1261 gaaccatgtc gattcccccg taccgcgtga ttaatgcctt ttttggggga tagtttgata
     1321 tagggacagg agagatcaca tttaaatacc ggatatacct gccctgcacg ggcccggata
     1381 tgtcccaaaa gaggtgcatg aaagtttttc gggtggaaga gaatggatcg ggaatctgca
     1441 atctccaaga atatcctgct ggcactggtt gcggcagtcg ccatcatcct cgtcgtcatc
     1501 gtggcggtgt tcatcttttt cccaccgcaa ccggacgtgg taccccagtt tacggcaacg
     1561 atagaacgtt cgggaaatac cgtctacatt taccatgacg ggggagaccc tctccagagc
     1621 agcaggacac tcatccggat caacgggcag accattcccc cgaattacat ctccttcctc
     1681 cactcccagg actggccatg gacccaggga aagacggtgc gcgtcctgta tgacgggccg
     1741 ggcacgcctg acctcgtgga agtcgtctat tccggttcga aaggggagat cgttgtattc
     1801 agtgacaggg caccctccgg tactcctccg acgatagccg tcacgaccgt tgagacagtc
     1861 cccgttacag cgacaccggc accttcagag gtcattcctg tcgtaacggc atctcccccg
     1921 ggaccggtga gccctgcacc accccaggcc ggtttcatcg gcgaaccgag aaccgggcag
     1981 gttcccctca tcgtccggtt catggacatg agtggcgggt ctcccacggc gtggctgtgg
     2041 aacttcgggg acggggagac atcgaccgag cagaaccccg tgcatgaata cgcaaggagc
     2101 gggacgtaca ctgttgccct gaccgtccgc aaccagttcg ggaccggcca gaaagtcgag
     2161 aaagactaca taaaggcagg aatcctcccg aaggcacagt ttgctgttgt tccctccgag
     2221 ggcgaggcgc cgctcacggt ccagttcaac gatctctcga ccggcgttcc cacggcgttc
     2281 tcctgggact tcggagatgg ttccggttcc gtcgagcaga atcccgttca cacctatgtc
     2341 aaggagggtg actataccgt cagcctcacc gtcagtaacc agttcgggtc cgacacccgc
     2401 atccagagcg gtgcggtcag ggtctcaccg gccaaaaagg tggatgtcct cctgtccgga
     2461 agtcgcaggg gcactctctc gacagggttc atccagttca ccgtcacggg acggcccgcc
     2521 tggatcaaga ttgggggcac gcgttacgac ttctccccgc aggacatcgt ccaggtattc
     2581 atagacaaga gcgagagcgg aaccatcgat gtgaatgcca atggcctgac aggtttgaaa
     2641 tttgacgctg cccggctgtt cgtgaacgga aacccggtac ggagtggcat tgtcaacgat
     2701 atcaatgtcc cctcgtactc cggggtctcc tcgaccctcg tgatcgagat tgccccgggt
     2761 gaccagacaa tgaccctctt tgtcgatgag gggaggatcc tctctgcccc ggaccaaaag
     2821 attctcatca gtaacctctg cgagaattca gacgggcaga tgagcctccg gataatcccg
     2881 ggtgccctcg aataccgtgg cggggcacgc gggttcagcg ttgtcccggt atcgtaagaa
     2941 aactcccacc gtttttttct gcctctccat catttcgagt acttctgttt ttcacgattc
     3001 gctcacatcg gaaagagagt attcattccc tttcagaatg caggaaggta acagaggcac
     3061 agttcaaaag gggattcaaa aacgcctgtc ttcaggctac agggaggatg aagcccggct
     3121 tcctcacacg gacagcgaga ggtcccgcag cctctgggag acgaaatcga cgagttcctt
     3181 cgattcattc cgggcaaatt tcaggaaacc ctcgtatgcc gcgatggctt cctctgtcat
     3241 tgacagtttc tcgtacgcga gtgccttgtt caggaatgcc cgtgcataac cgggttttac
     3301 cccgagggcc cggtcaaatt cccgaatcgc ttccctgcac atgttcctgt tgtaatagat
     3361 attgcccatg ttatagtatg cctcggcgag gtccggacgg agcccgacag ccttcgagaa
     3421 gtccgcaatg gcttcatcga agaacccctt cttgccgtac tcgatccccc ggttgtaata
     3481 cgccgtcggg ttgtcggggt tgatctcgat ggcacgcgag aagtccgaga cggcctcgtt
     3541 gtacatcccg agggctgcat gcgcattccc acggttattg tatgcttttt cgttggcggg
     3601 ggagatctgg atggccctcg agtagtcggc gatcgcttcc tcgtacctct cgaccctctg
     3661 gtaggcaaca ccacggttgt aataggcctc ggcaaggtca ggcttgatgg ctatcgcgcg
     3721 tgaaaaatcc tccattgcct tttctatcaa tcccttcttg ccgtactcga tcccccggtt
     3781 gtaatacgcc gtcgggttgt cggggttgat ctcgatggca cgcgagaaat cctctatcgc
     3841 ctcgtcgtac atcccgaggg ctgcatgcgc attcccacgg ttattgtagg ccttctcgtt
     3901 atcagggctc agctcgaggg cccggttata atcggctatt gcttcctcca gcatcccctt
     3961 cttgtggtag gcaacgcccc tgttgtaata ggcctctgca aggtcagggc ggagcatcac
     4021 tgctttccca aggtccttga tagcctcgtc gagcatgccc ctctcgccgt actcgattcc
     4081 cctgttatag aaagcaaccg cgttaccggg gttgatctcg ataacccggg aaaagtcggc
     4141 gattgcctcg gatgagaggc ccctgcctgc caggaggttg ccgcggttga tgtacgcctt
     4201 ttcatgaccg gggtcgatct cgatgacctt cgagtaatcg gcaattgcct catcgatcat
     4261 acccagccgt tcgtagagca ggccgcgagc aaggaggatg cttacgtccc ccggagcctg
     4321 ttcaagtgcc cgggaaaggt cttcgacagc atcctcgtac ctccccagcc ggctgtactc
     4381 tgtcgccctc gcagtgagcg cttccacgga gcggccattg aggcgtattg cattggaata
     4441 gtcctctact gccttttctg cctgtccgca cctgctcctc tcctgccccc tcccgatgta
     4501 cgcatcgaac aaccgcgggt cgatctccag ggcacgggaa aaatcggcga ttgcctcgga
     4561 tgaatttccc agttcggaat tctggcgccc gcggataagg tatgcctgtg catccgcagg
     4621 gcgtaactcg atgacgcggg agatgtcgct tgcagactcc tcgaagcgac cctgtttctg
     4681 caggatcagg gctctctgga agtatgcatc cgcgttcgag ggctccatcc cgattgcctt
     4741 cgaaaaatcg gcaagagcct cctctatctt cccggaacgg gactgctcga tacctctccg
     4801 gacgtacagc ccggcactgg tgggctcgag ggcaagtgcc gctgtcaggt cctctgttgc
     4861 acgctcggaa aggcccttcc gggaatactg ttcggcacgt gcgacgaggg cctcgaaaaa
     4921 ctggccccgt atctccagtg cccgcgaaaa gtccctgaca gccatgtcgg agaggcctat
     4981 ttttgcaaat tcgcatcccc tctggtagag cgcatccggg tatgcaggcc ggatctcgag
     5041 tgccttcgta aactcggata tggccctgtc agagaggttg gctttctggt actcgatacc
     5101 acgggcaaaa cacgcctcgg caaacttggg gttgatcttc agggcgtggg tataatcagc
     5161 gatcgcttcg tccaccattc cgagccggtc atactcgttg cccctgttga aatatgcctc
     5221 gatgtaaccg ggatcgatat cgatggcgcg tgtaaaatcc tcgattgcct tttcggactg
     5281 cccgagcctt gagtattcga cacccctccg gttgtagagt tcggggtcat cgggagaccg
     5341 gtttatctca tcggtcagct gccggattgc agggtcttcc accagttctt ccaccggggg
     5401 aacggttgtt tctccctttt cctcctcgcc ggggacaccc tggccgggag ctgtctctgc
     5461 cgccatcccg gaaagggagg cctccggttg cgcggtgact gcttctgcct gcgtctcctc
     5521 cgagattatc tcgagtgccc gtgaaaactc agctatcgct tcgtcaaacc tgcccatgcg
     5581 gttgaagagc acccccctgt tgttataggc ctccacgaac gaggggttga tctctattgc
     5641 ctttgcataa tggtcaaggg cagtctcgag gaggccgaga tggctgtatt caaccccgag
     5701 attgttgtgg gcctccgcat aggcggggtt cttctcgagg cactggaggt aatctgcaat
     5761 cgcagcctcg gactgcccga gcttgccgta tgcgaggccc cggttgtaga ggatatctgc
     5821 tttttccggc gtgatctcaa gggccctcgt atagtcagcg atcgcgtcct cgaagtggcc
     5881 caggcgggag aattcgattc cgcggttgaa gagggcctcg gaaaacgagg gatccagttc
     5941 gaatgcccgt gtatagtcct cgatggcctt ctcgtgcatc cccctgcggg catagataac
     6001 tcccctgtta ttgtaggccg ccgcgtagga cgggtttagg gagattgcct tcgaaaagtc
     6061 agcgatggca agttcatatt ccccgatccg tgcatactca agtcccctgt tgtagtaagc
     6121 ctccacaaag tccgtgtcga ggttgaccgc actcgtgaaa tcggatattg cattttccgg
     6181 ccggttcagg agggaatagg caactccgcg gttgtaaaaa gcctcggaaa aatgggggtt
     6241 tatcctgatg gctgcgctgt aatcttcaat tgctcccggg tagtcatgct tgcctgcttt
     6301 tgccacaccc ctgttatggt atgcctccgc atcgtcagga ttgatctcga tggcccgggt
     6361 gtaatcggcg attgcttcgt caaaaagtcc cttcttgtgg tacgcgatac cacggttgta
     6421 atagatctcc ccgtccatca gcagaagtcc cccggatggg aatcactcag gaacacttga
     6481 gatttctacc cctcatactg gatgtgtcac ccagataatt aattatattc ccctctcttt
     6541 ggtgattgag ccccggggat gcacaaggag ggggaaagaa ccatccaatt cgtaaaaaat
     6601 atagagggtg gggacttacc attcacagca acaattccct tcagtggttg tcctttccgg
     6661 atgttattcc cccggttgcc cggatacctg ccggttcctg tcctggaggg ggatcgtaat
     6721 cgagtttcca agtaaacctg aggtgagaca gacgtgcagt ggtcaaggtc atttccgttc
     6781 cttttcctgg taatctgcat ggcagggctc attgtccctg cctgggcaga catccagagt
     6841 gttgtccttt acaaaacaga cttttcagag aacccgggct ggatgacgaa cagtccctcg
     6901 cggtattact gggacagtga ccgggagatg taccatttca ggacggaggg gggaacaaac
     6961 gggtacgcct acgtacccct caggtacgat gaccagtcct ttaccctcga ctacgacgtg
     7021 atcgtccttg tatcccagcc gaacagtgcg ttccggttcg ggctcacgag ctccgagatg
     7081 gactttacgc gggggacgac gatcctttct gcccttgaga acggaaaata cgggaaactt
     7141 ttctcgttgc gtgtcattga ccagaacaac cagttgcggg agatatccag ttactatgct
     7201 tcctactgtg gaagcctgac gggatgcgac acggtcgagt tccgggagaa taccacgtac
     7261 cacgtaacgg tgcgatacaa cagggaactc cgcaatgcag acatcaaggt cgttcggaag
     7321 gataccggag aagtcgtctt tggctacttt gtccccgtgg caaaggaact gctcttcatg
     7381 gaccggctgg caataacgac gaagggagac tacctcccgg gatcatattc cgagggctat
     7441 atcgataatg tcgaactctc gataatgaca caggttaccc cgacaccgac acctccgccg
     7501 gcaaccgtga ccgcgaccag taccactgca acgaccatac cgacgccctc ccccgaacgg
     7561 acaacgagtc ccactccgac gcagactgcg cccgttcctg ccctcattgt cgttgtctcc
     7621 ctggcagtat caggaggaat cgcggtttcc ctgaggctga agaaggatgc ctgattgcag
     7681 gatattacag tcatccttat ctcatccgca agggaaaaat tccggagaac atgacagagc
     7741 ccgcacgtga cgagcacgtc atcgaggcca tcgggaaagc ccgggtcgtg atccggaatg
     7801 gaaaggtcat ttccgtgggg gaacccctga tcagcgaatg cccgctcgca cgccggttcg
     7861 gaaaaccggt cccggtcatc actcccgggg caatcgggga gaacatggag tacaggatac
     7921 gggcgttcgg gatgtgcacg ccggacaggg cgatcgaggc cgatggagac tacgtgggtt
     7981 tcggcgcatc ggagctcctc tcctgcgggc tctcttccgg cctcctcgat tgcgtggtca
     8041 tcgcgtgtga cggcgcagga actgtcatcg tcacgcgacc gtccctcgtc cagggcatcg
     8101 gcgggaggat gtcggggctt gtccgcacct cgccgattcc acaggtaatc cggaggatcc
     8161 aggaaaaagg gggaaccgtg tgtgaccctg ccgctgcctc catcgaccag gccgggggtg
     8221 tccggatggc ccgggagatg ggctattccc gtatcggtgt caccgtggca tccgccgggg
     8281 acgcccggtc agtacgggag gaatatcccg ggaccctcgt catcgcagtc cacacgaccg
     8341 gggtaacgga agaggaagct cgcatccttg cgaccagtgc agatatcatt accgcatgtg
     8401 catcccgcca cgtcaggaac gtggcaggcc cacgggcatt gctccaggcg ggggtctcga
     8461 tccctgtctt tgcgatgacg cgtgcaggca gggacctgat cctcgaaaag gtccgccagg
     8521 cacctgcccg ggtggtcatc agcaatgctc agctcccggc cacgcatgga gtcgaacctc
     8581 agccgcttgt ctgataatcg cccgtttcgt catatcaaaa ggtgagtccc acgagattta
     8641 cagcctttgc cggtttcgaa ccggatgccg gagaaaagaa atgccggcag ggtccccggc
     8701 agcgtcctct cctccaccct ccgccttccc cggacgtcac cattccatgc actaccctcg
     8761 cgcagaaccg tcgcacattc cggcctgatg ctccggatac gggaggctgc gtctttttcc
     8821 cggtgcacat gttctaccgg gaacggaccc acgcggaacg gctgtctcat ctttgcacca
     8881 cttttgcacg tttgcatacg tttgcacccc gctggtgcaa acgtgggaac tatcctgcac
     8941 gtccggattc gcgatcggaa ccttttcccg atatttctcg gcaacctttg caccatgtgc
     9001 aggatcgcac gcaccgggag agagactatc ctgttctgca ttcgtggtct gcgctccctg
     9061 taaatggtgc aaagatgccc gtgaaaaatt acctctcagg tacagtgtcc ccatttccgg
     9121 atccggggaa gaatatccat acttgtcgtt tgcattttcc gggtgcaaac cgggtgcaaa
     9181 ggtgcaaaca tcgtgcccgg aagccacccc accatttctt cccggtggag aagggagata
     9241 tttcctcttt gttgtgataa gatttttgat cggcggatac aaaagcagaa gactcgtagt
     9301 ccttgctgct gagacaccaa caggtctcct cctgatgatg caacgcgtca caatgccatg
     9361 gtagggagag cccgctattc ttgatgaaac ttcatctcca tcactggcca tggacagtcc
     9421 acagtgacag catgcttctt agcgccagac ccgttcgtaa tattcccagg aaacaggttt
     9481 tccgggcaga cccccaaatg catgaagaag atcgaaaaag ggggttttca ttgaaaagaa
     9541 actgtggaga aaagaacatg gtgttcgaat gcgagggatg ggtaattagt gaaatatcgg
     9601 catttcatgc ttatttttaa aaattaaaaa tgtaggggca attttcctat gcttgacaac
     9661 atatcaaagt ttagatgatt gggtaagcga aaatcgatat cgcgcagata agaacatcag
     9721 taactattga aaccattatc attgtttaaa cccccagccg tgaagaaata atctgggttc
     9781 aaatctctcc cggattttgg atcgcgcagg aattttcagt tataatcgat gactccaatt
     9841 tctgatggat atactgatgt cccatcataa agtttatcga tatacaattg tccatttgat
     9901 ttaattctat gaatccatat aaatctcgga tagtttttac aaagaaaatc cttcttttta
     9961 ttaaattgtt tatccaagag aaatctttta taatcgttta gttttactaa ttttaactca
    10021 tgagaatatt cgtctttcat ttctctttct tttttacgtt cctctatcat cctttgattt
    10081 cgtaaaaaga ccctgtatat cttgatataa ctcagtctca ttttatgata aataggaatt
    10141 agcagcatct gaagattaat ttcagaatat tttttctctg ttatccactc attttcccaa
    10201 ttacagatag attctttaag ttttgtttta caataaggcc cgatagcatc atcatgaata
    10261 tataattctg taatttttcc atccctatgg cgataaccac taataacaac cgcatgtttt
    10321 tctggatcgg gtctgccttc cttttttaat ttcaatgctc cgataattgg aataccataa
    10381 tcgagatacg cttttattgc attgccaata aaatcatcaa tactaacgtc ttttcggtta
    10441 gtttggatct tttcgacgtt tataaattct gtttctaacc caagagcgtt aaattggctc
    10501 ttcatttgat ggagtgtcaa tccctttgaa gggaaatttc gttcaagggt tggaaaagat
    10561 attgatgttt cagtaacttc caccggagat aattttggag tttcaaattg tttgcttaat
    10621 ggatacaaag cagtccaaca agcagtagtt gcacaacctc caactgcttc atcttgtgac
    10681 tggaaaggta aagaatcaat tgataaatct attccataaa gagatacatg aaatgtattt
    10741 gtcagatact ctcgaagttc accattgtca tctcgtggcc aagtacgcaa tagtgttctc
    10801 ccaatgaagg gctgattttc tctatccatt ataggtttaa taaccgtaaa tcccaaatac
    10861 gccttcttta atttatcatg aaaatctttg ttaaaattct ttaatccttc ataaaactct
    10921 ttattttcga tagattcatt aaagaagtgc agacgggttg taaatttttt atcgatatta
    10981 aaggaacgag cataaaattt tgagaagtcg attaaataat ctttgtctat ataattttct
    11041 tcaataaaaa ttgattttgg ctctaatttg ctttttaaat aattgtgaat ataataactt
    11101 tgatcagatt ttcccgcaac ttcaaaaaat ttatcaaaac cgatcaaaaa ggtaggttct
    11161 ttcatcttat accatactca aactgtaaat ggctcaaata gatcttccat actcattgtt
    11221 gtaaattctc tgtaccattc ttcagcttcg ttttttattt tagaatccaa tgtaagtatc
    11281 cttatcaaat catctttaaa gtccgtcatc ttctcacctc tcctatccat agaactaaga
    11341 caattagttt tactagtatt attatattta aaatctatca aaaaaaactc agaggttact
    11401 ataatactat ccaaaaaata actcaccaaa aaatgccatt ctttttttct ttcccactcc
    11461 cccagcctct catcgctttc agggggcact gctaccccct tttctcctcg tctttgagga
    11521 cgacctcctc ctctcccaac gaagaggtag taattacgat gactgccctc cagccaattc
    11581 ggtgtaacaa gaatttcaca gacctctgct cggttgacct gccggacggc aaagcgaagc
    11641 gaaagatgag tggccggtcg ggagaatcaa gcctggcggt cgtcatcgga cgacaaggat
    11701 aaccaggacc agcggatctg aggccactac cgaacgcagt gaggacgtcg gcggagcgaa
    11761 gcgatagaag accccggaca acttcccgca ggtgtagtcc tcgatgtgag cggaagcgaa
    11821 ccgtggccga gtcccgaagg gccaaatttt atattacgca ccatttcgaa tgcttcagat
    11881 attactttca tactacttgg cgccctttaa tgccctctgc cgacgctgat tccgacacaa
    11941 gaacatcttt cacaatgatc taacggatga gctgggcatc acgtataata acggtttcat
    12001 ttaaaaaagg gcggaatcga tgactcgaaa tgggtattca tgcttgatag aatgaaagac
    12061 ttggttgatg gatgtggttg gttctatgag aaaagggaaa aaggagctga taaattagca
    12121 gaaaaaacgt caatttgcat aaatgcgagg gatgggattt gaacccaaga actccttcga
    12181 gaccagcccc tcaagctggc gcctttgacc tggctcggca accctcgcgc gtgccataat
    12241 acatggatgc gttttcaaaa taaggttatc catcacctgc ttggcgggat gacacctgca
    12301 cccggctccc cgcatgggac cggagaaaaa cgcccaccag catgcccgga aggacatcga
    12361 tgaatggaaa cactcagtgg tgtatattta ttctcacgcg cgaatactca atcattatgt
    12421 ggtcggagat catccgggaa ttttctgatt ccccctccca ggcaaaagtc gttacttttc
    12481 tccttgaaaa cgggttctcg gtgaacgaac ggggccggat aaactgcaac ggactcgaga
    12541 taccgtccac gcaggtggca aaggcaatcc acacggacag gcgggtcgtt gatgcgacag
    12601 cgcagcgtat cctctccctc cccctccacc ggacagtttt ttcccacatg cgggtgactc
    12661 ccgacctctc ccgtgtggct gaccacctcg gtctctcggt gatgacgatc tatccgcggg
    12721 atgcaacgga aaaggggatc gtcagcgaag ccgtgcgtgt catatcggaa gccgggctct
    12781 ccatcaggca gatatacgtc acggaccctc tcctctccga ggacccgaaa ctcgtgatca
    12841 tcatcgaggg tgatttcccg ccccgggtca tcgagggtgt ccggcacctt ccccaggtca
    12901 ggaagatcgt cctgtgatta ttgggaacag tggaatcaca cccggttaat ccgaccgggt
    12961 aagcgacgtt tcaggagtgg gtccccaggg acatgtctcc ccgtcatgca cagtcccgga
    13021 aaagctccat ctccagccac aggcggaaga tccgcctttt caccttccgg gggaggttgc
    13081 aggccctcat catcctttct ccgatcccga tgacatgcgc atcggcaacg aggttgtccg
    13141 cattggcaac caccttctcc tcgggtgtcc gggggatgca gtcgacgggc aggaggcgga
    13201 ggagcgtgca ttcgtctgct gtcagccctg ccccggtatg acactcgacg atccgcacaa
    13261 tcccgtccgg gaggccctgt tcccggcagt acgctgcacc cttctgagcg tgggtgaggt
    13321 cgtgcgtgaa acccctgccg atatcatgga gcattgcacc tgtaagaaga atctcccggt
    13381 ccatgatacc gggtacaaag aaaccgaggg caaggtcaca gactgtatcg caatgccgga
    13441 taactctccg gctgcacccc gccctctcca ggagttcccg ccactcgtca cgccggtcag
    13501 gcattgcaca gtgattcttt gatggcctgg atcctctttt tcagggcccg gaggaggatt
    13561 tcgttgtcga agtgttcgag gggattgtcg caggagggac acttgaattc cgagtccatt
    13621 gccatgtcaa acgtaaatat atcgccacag gacttgcaga tatagaaatc gttctcttcc
    13681 tcgaaccgtg cacgggcctc gagtttttcg aggacctgtg ccatgtcttc tgcgatcacc
    13741 tcgtaaatcc tgtccatccg cagctgccag aggtacgtga gccacccggt ctcgttgttc
    13801 ttgatccggc ggtactccgc gagccgtttc tcgtaaagcg tgtaaagtgt atgcctgacg
    13861 gaattgaggt taatcccggt cttttctgca agttcctcat cggagtactc cccgtctccc
    13921 ggaaagctct cgatgaggga gatcccctcc tccccgacca gccggtccag gtacgtgtgg
    13981 atcgccggaa tagcgagtat atcttccata ggaccttcac cgaatgtatt gtcttactct
    14041 cctgatatgt ctatccaggt ggtgcatggc actctccggt gtgggtcccc acccgtacac
    14101 gctgactacc gcctggccct cctcgaaaaa cgtgcccggc cacggtatat cggagacggc
    14161 aggggagagt ccggagagat ccccgcttat tgtgcagtcc ctttcggcaa agaggatgcg
    14221 acggatgcaa aaacaggacg ggtttggtac cttgtccgga agctctcccc ggcaggcccg
    14281 gacatgggct gaaaagaggt taaggccaag agatctctcc acggtatcga gagttgcctg
    14341 gaaccggggg tttacctcga tcgcgtggat atcctccccg atgacaaagt cgacaccgag
    14401 ggacccgcaa cacccggatg atgctgcgac cttttccgca tacgcgatca tccgtggcgc
    14461 gaggggatgt tcgaggggtg tttgcgaccc gcagaaccca aatgccgaca ctccttcatc
    14521 ccggaggatc tgcctgtttg cagcgagtgc acgggcgttt cccttcccgt ccgcaaggca
    14581 cgaaacggac gccggtatgc cgctgacgat ttcctgcgat atcgattcca tcccttcgaa
    14641 ctcttcgtgc cacagggatt cttcctcacg ggagcacacg accctgttcc tccaccctcc
    14701 cgaaccggat cgcggcttga tcatggcagg atactggcca tcggggagca accgggggac
    14761 aggaaccccg agtgattcga agaactcctg cgtggacacc ttgtcgagga accttgccgc
    14821 cacctccggg gatattccaa gaacgggcaa accgtgtgca agggtttctg cgcccgatgt
    14881 gggaactgcc cagtcgatcc ggtacttgcc gcacatttcc tggacggccg agggcagatc
    14941 ggccagctca tcgaagcgta tcctgtcccg ggtataccag gaaaggtcct ggtcacagaa
    15001 atggtcgact gcatacacgg tgtagccggc ctcgtgcgcg gactgagcca cgtggcgcgt
    15061 ggaaaaaccc atcacgagga tggaagggtt catatctcct cgcaccgttt ccccctcggc
    15121 gagggaacga ccctgatccg tgccccggga aactcccacg cgagttccct tccctcgaac
    15181 aggcgatcga gaaagacagc gagccctgca acttccgagt gcggctggtt cgtcaccgcg
    15241 atgttgtaat cggcaagaag gtagatctcc ccgggtacct tctcggcacc gacgacgacg
    15301 agtatccggt cattctcccg gatatccgcc acccgttcct ggacaggctc gccgtacatc
    15361 gtcaggtgga caacgacccc accggacgcc ttccattccc ggatgcactt cttccacggg
    15421 acgccgtcct cgacgaagaa atcgccgccc cagcgggaga caacgtcccg aatccctgca
    15481 acaattcctg catcccgtcc cgcgaggtac atcccccggg cgccgagggc gcgggctgtc
    15541 aggccgacgt gcgttgtcac tctctggtcc ctttcggggc ggtgcccgag gcggagcacg
    15601 cggacatcct tcattcgtcc ggctcccggt catttttcag cttgatgacg cctccctcga
    15661 tgacaaacgg gatatccctg cagtaacgtg cctggcagcg gatgagcatc tcctggacgg
    15721 agagaacccg aaaactacct ccatccccct gttcgatgag gaatgccctc tcgagccgtt
    15781 ggagcgatgc ctggatctcg gacggtgaac gcccgaggtg agcagcaagg aacccggcat
    15841 cgcgcgcagg gtctgccacg atgaggtggt aaacctccca gtccagatct tcttccctca
    15901 tggcctgctg gtgcataagg taccgcatcc gaaatgataa ttctcgtggt acccctaccg
    15961 cgtcccctgc acgttcacgg ttcccctttt ccctctgcac tgcctgtatg cacagggaaa
    16021 aacccgatcc cacggtcttg catgtctcca gcggtcgcac tacctatatg catccggaga
    16081 gtccacctcc cagtcatgca gcaggaggac gaggggaagc tgtcccaggg tgaacttgca
    16141 gacatcgcgg atgatatcct cgagagggtc ggggaagatg tcgatgccct tgcaggggaa
    16201 ctcgacatgc ttgacccggc cgtccgccgc cagctccttg tctccgattt cctgaatgca
    16261 ttccaggtgt attactactt ttacaggaag gccccgggtg aactcgaact ggagaggctt
    16321 ctcctccagc ccgcatctgc gcttgcccat ggtgttcttc tcaccgagct ggaccttttc
    16381 gtggtcatgt tccgggtgga agaaggccgg ccgatcatca gtgtcggtga cggggagaga
    16441 atccttgcca acttccggga gaaggacgcc tacgataaag ctctccggtt catcgacgaa
    16501 tccgcatgaa tgcacatgac aatgtcaggg aggacaatgg cgtgtttttc gcgggagacc
    16561 atggcaaggc attcctctcc gcctgcggca gtatgaacga tggctccttc catcccggag
    16621 aacattttga ggataccggt tattcccggg ttatcgtcca cgacaagaat cttttgtgcc
    16681 atcgttcttt tcctaccagg gaccacctgt gacgaggtcc cggtcgacgc gtgccctgac
    16741 gatgggggga agcgtccctt ccttgtgtat ccagttcccc tcgatcacga ggactccctc
    16801 tatgcgatcc caggggacac gcccgagcat gtgctggtct tctcgcgaga cagaattgca
    16861 gagcgccgtt gcccatgcat cggcaaggca cgggtcaggg gagatgacgc agacggcgtc
    16921 cgcagacccg aaggatatcg acggtcccac cgttgcagaa gacgtgcata tcccgaggat
    16981 acggtcctgc gggggaaccc ggaaggcaat ggtgtcgctg tagggggatg tcccggcatg
    17041 gataccgact gtgagggtcc ggtccgagac gagcgcgata tccccgccgt tgtcgatgac
    17101 tgcgaggcgt gctcctcccc ggatcatctc ctcgacacct gcacgggcta tcgcaccggc
    17161 cactgctgcc atgggaccga cacctgccga tacaccggca tccgccatcc tgtccacgat
    17221 ggcaatcccg gtatggagag ggtatggttc cagggttgcc acgaaaaaag ggtcacctgc
    17281 gatataccgt tccaggtcct gccgggcact catcagcccc cgccgcgcgg cctccacgtc
    17341 ctcgtcccgt tctgcaagga tcgtggcgat tgtctccctg aaggcaaacc ggtgacgaat
    17401 cacaacagtc tggtattgtc cctgcagggg aaaaaacctc gagtgtaccc cggtgtattc
    17461 cgaacaggtt attcacaccc gcaatcaaga cctctgggag agagatggtg tcatggatgc
    17521 atgcgggcca tcgccggtcc cgcaccgggg cccgccggct cccggcctat atcgtcgtcc
    17581 tctgcgtcga gtggcccgga ctggagaggt tgcaggatct tgtcgcacag gaggtgggac
    17641 tggcccgtga ccagcgtttc ttccctcatg tcaccctctg cggcccactt ctgctccacc
    17701 ccggcacgga tatcgtggca gttctcgacc gggctgttgc gtccctttcc atgacccgga
    17761 tcgtccaccc ggtggatctc catctcttca ggggaaaacg gggacttgca gtctcgctcc
    17821 tcctgcagga ggatgcgaca ctcaccgcgt ttgcccgcgc tgtgagcgat gcccttgccc
    17881 cgttttccaa aaaaagcaac cccatcgata tacccccgtc gaagcggatc cttcacatct
    17941 cggtcgcggt caacctttcc cggcaaaagg gagaactcgt cttctcgaaa cttgcagacc
    18001 ccggcgggaa accgggcagg gagaaagaat tgctcttccg ggagacgcct ccccggatca
    18061 cgcgcatggc tctcatccgc aggggtgccc tgtggaaggc gtacgacctc ttccagaaaa
    18121 agtggattgg ccggaacgga ctgttcgaag cagaaaaacg cgggagaagg taaattatct
    18181 cctctcagtc attccgggcg gctctcaggc cggtcctttc cgcgacaggg cacggtgagg
    18241 gcagatctcg atgcaccttc cgcagaggac acattttctg gcgtccatct gcagcctgaa
    18301 atcgctgtcg aaggagaaga cctcctgggg acagatgctg atgcacgcac cgcagtccac
    18361 gcactcggtc tcgtcgagga tgatctcctc ctcgaggatg cggactgatg caccgagatc
    18421 ggtgagcctg tccttcacga tgcgacacga ctcgtcggga atgtcgatga gggcctcgcc
    18481 ctcgctcgaa tcgatcaggg cgcgctcgac gttgacaagg acaccggtgt ccctgacgac
    18541 ctgcgcgatg atgggttttc tgccctcctt ccgggagaaa gtgacaagga gcttcacttg
    18601 agccacctcc ccccgaagag cttgccaagg tccattgccg tgagtatccc gacgacgtgc
    18661 atctccctgt caacgacggg gagggcactg atattatact tttcgagctt gcggatcgcg
    18721 atatcgacag actcctccgg agtcgtggtt atcactttcc gtttcatgat gtccctgaca
    18781 aagttccctt tccccgggtt gaccacggct ttcgagatgt catacgtcgt cacgataccg
    18841 acgaggaccc cgtttccgtt gacgaccggg agatggttgg tctctccctt caggagcttt
    18901 gctgccgcgt ccctgatggg ttcgtcttcc ccgatcgtcg cgacacgcct ctccatgatc
    18961 tggagaacgc gcgggccctg gaccgtctcc ttcatcggtt ctgccttccg cccgggatcg
    19021 agcggcctcg tggggagtgc gagtgtcatc ctgccggact ctacccatcc cttcagctcc
    19081 gctgcgacca tcctcgcccg gcggaaactc gacagggacg acgtgcggat ctcttctccg
    19141 ccgatctcca cccgcccgct ccggagcatg gcataggaga cacgcccgag ggacggtcgg
    19201 gaacgcgagg ggacgctgta atcgataata tcgacccata tgtcctcgtc gcgcacggct
    19261 gtgctccgca cggtctcaat atccaggacg gggataggaa ttccgagccc cacgtagagc
    19321 gtgaccccgt accctgtcat cgtggctgcc cggaggtact cggttttcat ctttttgagg
    19381 tccccggtta ccatgagggt tccaaacccg gtcgccgggg aggcctgcgt cccctcgcca
    19441 acgaccatcc cctctgcacc gccgagaaaa cagggaactc cctgcccgat gacgcgcaag
    19501 tgcgggtcgt ttgcgagcgg gttgagtaca cccgcccccg agtaggtgat atttccaagg
    19561 gacgggagga gcatgcccat gtacgtgtgc aggacacggt cacccgagtt gccggcagca
    19621 ttgtatctct ggtacccgtt cctcgggttg accatgatgg cctggttaca gttctcgagc
    19681 aggatctcgg tcgtgatggt gcgccggggg taacagtcgg ttcccctcga tatggcccgc
    19741 agttccaccg accttccggc agcgagatcc tcgaggacat gggctccccc gtagttctcc
    19801 tccctcgtcg tggacttctc ggtcgctccc aggtacgcat cgacggctgc gatacctgca
    19861 tatgcctcca cgtcgttgag ccagaccttc tccatccgga tcggggggtc ggcatggccg
    19921 aagttgaaaa aacatcccga ggaacacatt gccccgaaag tccctgtcgt gaccacgtct
    19981 acctctgcaa gggctccctc ttcgccgagt tccgcgacga tctgcggcat ctcctcggca
    20041 gtgaccaccc gtgcattacc ctccttaatc cgttcgttta tctcctggat ggtcttgcgc
    20101 atggcatgat gttttaaaat gaatatttat agatgtttcg tattactcat agtaataaac
    20161 ctttgattat cccccgtgca cacaccatag tgatggatat ctcgcagttc ctcgccctca
    20221 tggaggacat tgcacctccc ggccttgccg aggagtggga tctgggacgg ataggactcg
    20281 ttgtcgaggg tgacagggac atagaaagga tctcctgtgc actcgatgcg acccccgccg
    20341 tcctccggga agcggttggt tccggctcgg atatgcttgt cgtgcatcat acgcccctct
    20401 ggacacccgt gacatccgtg gcaggggccc tcgcatcact cctccggcct gtcctttcgt
    20461 cagggatgca catctacgtc atccattcca atttcgacca cgcacccggc gggatcaacg
    20521 atgcactcgc aaaacttctc cggatggaga acatccaacc cctttccctt ggtgtcgtcg
    20581 gcgactgccc cctctcccct ttggacattg cagggattct ggactgccct gttgtcacgt
    20641 ggggcaaccc ggacctcccg gggagacttg cccttgcagg gggatccgca ttctccccgg
    20701 atctcatctc ggaggctgcc tgcaaggggg cacgtgcatt cctgtctgcc gatctgaaac
    20761 attccgttgc tcgggaatct cccctcccgc tgctcgaagc aacccactat gccctcgagt
    20821 ccccgggcat gagggcgctt gcggagcgga tggggtggac atacatcgac gatccgccgg
    20881 ttgtcaggac atggaacccg acgagttctg ggaacgacta aaagaggagc gctgcctgac
    20941 cccccggctc cgggaggaac tcctccggat atacggtgag cggggaaaaa aggcactcga
    21001 agccatcgat tccggccggg tgatgcagta cagggacttc gtcgttgttg ccgggaagtc
    21061 ggaccagtac atcgtggagg acgatttctg cacgtgccac gatcacctct accgccgggg
    21121 actctgctgg cacctcctcg cggtccgcct ggcagcaact gccggcgggt tccggcaggt
    21181 tgcggaatgg taccaggaga agtggataca aaagcgtggg taaagccaac aatttttatc
    21241 gtttcaagcc gaattaaatc agaacacgtg gttttatgct cgaagaggag taccagctcg
    21301 aatatttcaa gacccagggg ctcacccgca aaatatgctc caggtgtggt gcagcgttct
    21361 ggacacggga ccctgatacc ctgacgtgtg gcgatgcccc gtgcgagaca tacaggttca
    21421 tcggggcacc ggttttcagg tgccacaccg tcgacgagat gcgggaggcg ttcctctcct
    21481 tcttcgagca gaacggtcac acccggattg cgaggtaccc tgttgcagca cggtggaggg
    21541 acgatattta tctcaccata gcctccatcg ccgatttcca gccgtgggtg acgagcggta
    21601 tcgtgccacc acccgccaac ccgctgacca tctcccagcc ctgcatcagg ctcaacgacc
    21661 tcgactcggt cggcaggtcg gggcgccacc tcaccctctt cgagatgatg gcgcaccatg
    21721 cgttcaaccg cgagggcgag gagatatact ggaaggaaag gacagtcgag ctttgcgaaa
    21781 agttcctctc gtcgatcggc gcggatctct cgcgcgtgac ctacaaggag cacccctgga
    21841 taggcggcgg gaacgcaggg ccgagcctcg aagtcctgat agggggactt gaggtcgcca
    21901 cgctcgtgtt catgaacctc gggcggacaa agaccggcaa gcccggtatc gatctcggcg
    21961 gggagacgta ctaccccatg tccaattaca tcgtggacac gggttacgga ctggagaggt
    22021 tcgtctgggc atcgaggggt tccccgacca tatacgatgc agtcttcccg gagatggtca
    22081 gcagggtgat ggaagcagcc ggccttgcgc acgccctcga ggacaaggag tacaccaaga
    22141 tcctctccct gaatgcgcgg tttgccgggg tgatggatat atccgggaca aacctctggc
    22201 agctgcgcaa gaaggttgca accgcaatca acgtgcccat cgagcggctt gaccggatga
    22261 ttgccccggt ggagaaggta tacgccatcg tggaccatac ccggtgcctc gcgtacatgc
    22321 tcggggactg catcgtcccc tcgaatgtgc gggagggcta cctcgtccgg ctcgtcctgc
    22381 gccgcacgct ccggatgatg aaggaactcg ggataaagga gtcccttgct gacctgatcg
    22441 aggagcagat gaaaattgtc ggaacgggtg cattcgagca ggacatctgc atcgtccgcg
    22501 agatcgtcga gcgcgaggtg gaaaagagca atgccacgct cgagaggggg acaaagatcg
    22561 tccagaggat cgcccggacg tataaatcga ggcgtgaacg tgtccccctc cgggaggtga
    22621 tcacgctcta cgactcccac ggcatcccgc ccgagatcat cagggaggtt gcaaccgcgg
    22681 aaggagccgt tgtcgaactc ccggacaact tctactcgct catcgccgag atgcactcgg
    22741 agtccgagcc ggaagaggag gaggatccct ttgcccggta cagcgagagg atttcgatgc
    22801 ttcctgcaac aaggaggctc tactacgagc agccttccga catggagttc gatgccatgg
    22861 tcatcgactt cttcgacggt tacgcggtca tggaccagac actcttctac cccgaggggg
    22921 gtgggcagcc ctccgatacg gggatgctga tctctgcaga gaacatggtc aaggtcgacg
    22981 atgtccggaa ggtaggagac gtcatcctcc accacgtgac cggcggggtc cttcgccggg
    23041 gagaccacgt gaagggtatc attgacgagg aacgccggtg gtccctgatg cgccaccaca
    23101 cggcaaccca catcctcctg catgcctcaa aggaggttct cggggcccac atccaccagg
    23161 ccggtgcaca gaaggggccg gagagctcgc gcctcgatat caggcactac aagcacatca
    23221 cgccggatga actgcgcaag atagagatcg ctgcaaaccg gatggtcatg gcagaccttc
    23281 ccatcgatgt caagtacctc gacaggacga aggcagagca gatgtacggg ttctccctct
    23341 accagggcgg cgtccccccc ggaaaggaga tccgcgtcgt gcgggtggca ggagatgtcg
    23401 aggcctgtgc aggaacgcac tgccgcagca cgggggatgt cgggttcatc aaggtcatca
    23461 gggtggaaca catccaggac gggatcgagc gtctcgagtt cgccgccggc cttgcagcag
    23521 tcgagtacgt gcaccgtatc gagaagatcc tctccgggtc agcagaaatc ctctccgtcc
    23581 agaacgagta cctgcctgca accgtgaaca ggttcttctc cgagtggaag gcccagaaga
    23641 aggagataga gcggcttcgc cagcgtatcg ctgaactcga gaagaaatcc cttgctgccg
    23701 aggtcgtggg caatacccct gtccttgtca ggcggatcga cctttcaggc aaggaacttg
    23761 ccacgatcgg tcatgaaatt gcggcccgcg gcggcgttgc actccttgcc agcggttcgg
    23821 accaggctac cgtcctgctc atgtcagggt cagacagggt caatgccggt gagctcataa
    23881 aggatgtgtg tgcggtcctc ggagggaaag gcggaggatc ccccgcaatg gcgaggggtg
    23941 gcggccccgc tgtcgagaag atcgaggaag cactcgccat cggaaagcag aagattatcg
    24001 catcactcgg aacgtaagcg gggaggaaaa tatggagagc agcagcgagg atacgggttc
    24061 cggtcagccg gatcccaacg cacccgatgg cgaggtggtc atactcgtcc ccggtgacga
    24121 gcgttcccag aagattgcaa aggccatctc gagccaggca gcaggcgata ttctccatgc
    24181 cctcgagagg ggacccagaa cggcagggga tcttgcctct gccctcgcca tgccgatggg
    24241 aaccgtgaaa taccacatcg aaaacctcct cgaagcaggg ttaatcgaag tcagggacac
    24301 aaagtacagc gtgaaaggcc ggcaggtcaa ggtgtacggg ctgcgcaacc agctcctgat
    24361 catggccccg agggtccgga acatccgatc catcctcctg cggtatgcgg cccttttcag
    24421 tgtcgttacc ctctcctcgc ttgcaatgta cgcggttctt gccgcatcgc gcctctcggc
    24481 agcaggattc ggcgaggggg acagggcaaa cttccaggca gagaaaacag ccggcattct
    24541 cgctgccccg accccggcac cgacacctga accctatccc ttctcacagg cactccctgc
    24601 cgatattgca ctcgcgttct ttttcggggg tgtgctcgtc ctcatcatcc tcctgctcta
    24661 cgaggtctcc gtctggcgca ggatgaagtg accgggtttc ccctgcctgt cacttcttcc
    24721 tgtgcacgca aaaaacaagc gcaatgatga tcagaccggc aattgctccc gcaacaggga
    24781 agggagagac tgcagtggct gtcggagacg gagattccgt ggtcgtccca tgggttatct
    24841 ccgtggatgg aactgctgtc ccgcccggtt cactgaccgt gaacttcacg gttgtgatgt
    24901 agcccttcac gtcggagaag tccacgtaat agttcccctt ctcgctgacg ggaatcgtcc
    24961 tgctgaagaa accatcgtcc tttccaagaa ctgtcgttgt cctgatgtcc tccggcggga
    25021 tgactgcgcc ctgcggcccg gtaaccttca tcgtcagggt gacaaccccg ccccgcggga
    25081 cgtatccctc gatccggagc gcttcgccga tcacctggtc ttttgccgaa gtgatcacga
    25141 tctcccccga cctgtccgtt attgtaagca tccgcgtcgt gaccgagcct gaactcagtt
    25201 tcgagcccgg gtcggagcgg aacctgacct cgaccttgta ttcgccggga gaaagcccca
    25261 tcgttgggaa ggtgatttcg aatgactttg aatcgctcac aacgactgtc ttttcaaaga
    25321 caggttccgg catcgtcgtc tggatccggt acaataccag gtcaaactcg gtaccgaccg
    25381 ggaaggtcgt gttccccgtg acctcgaccg gaacaccggc ccggacttcc tttggtgcct
    25441 ggatcgtgag ttcgtacgcc agcacaccct ggacaaggca gaggatgcag agcagggaaa
    25501 aaaccgcact tttcatggga tcgtctgggc ggtctgacga taattagttt ctgccccgga
    25561 tggcatgcac cgggccggag gaattccggc aaggaacagc ggccggcatg ctctttccgt
    25621 caggggatcc cggcagatac tatataagat gcgagcgcat cttcttcacg tatggagtcc
    25681 atcactctga aagttcagga aagggccttt ccaagcaggg ggagggccag gatcaacgag
    25741 gtgcatttaa agaccctcgg gatcagcgaa ggcgacagtg tcgaggtctc tgcaggatcg
    25801 gataagaaac ccgttgtcgt cactgtcttt gcagacaagc tggtcgaaga ggggtacatc
    25861 aggttaagcc cggaagatat cgcacaggcc ggtgccatgt ctggcgctgt ggtgacggtg
    25921 acacgggttc cccccgtttc cgaacgtgtc aaaaagacag cagacaaggc aaaagagagc
    25981 gtcgcaaagg atgtaaagaa ggcaaaggaa gtcatctcga aaaaatcgtc ggaagcaaaa
    26041 gaatcgatgg aaaaaggtgt cgaatctgcg aaaaaaagcc tccatgaaaa agacctctaa
    26101 tcccgggaga ccagatcaat gacagacatg tgggtgattt tcgaagggat cctcccctat
    26161 ctcctcgttt tcatcggcct gatcatcgtg tatttcatca tcagggagtt ccgcctgatg
    26221 tattcgagga cacggctcgc gcagctcgaa ctcgaacggg agaagatcaa cctcctcaag
    26281 gcagacctgg aacagcgggg acgaccgttc taccgggtat ctccccagga tctcgaggag
    26341 ttaaaaaggc tcgacgagga gaacgtggaa ctggagaccg atatatttgc acggcacact
    26401 gccgttgaaa agaggttgaa gcggctcgag agcagggtcg ctctcacgaa gctcgaccgg
    26461 atgatagaga agataaaacg cgaagaggaa aggctggggt gagacaggtg accgaatacg
    26521 ggactccggg caggacgaca gagaagtatc ccctgctgga atcgataaag gaaataccgg
    26581 cagtcatcga tgagcatctc ccgacgatgg acaaggggct cgacgaatat ttcaaccggc
    26641 atttcccggc gatcatcagc gagtgggggc tcgtgacctc cattcacctg aaaaacctgg
    26701 aacggaggct tgaccgtgtg cacaggcaga tcgatgtcct cgagaagaac caaaaagcac
    26761 tcgaaaagag ggctgccgcc ctcgataaag aactgagggg gctcgaggga cgatgaggcg
    26821 cccggactac cttggttcct acgtggaccg tcgcatgaag tacctgatcg aggaatggga
    26881 tctcgcaacc cggcgggatc tcggggacct cgtatcccgc ctctcctccc tcgaggagga
    26941 gtcccggctg tgtgcagggt tcgaggcgac tgcgtcggca aagcttaccg aacttgaaaa
    27001 gaggctcgag tatatcaggg ggaggcggaa atgacgatca tcgaagggct cctcgtcctc
    27061 attctcatcg ctgtcatagc atttaccctc tattattact tcagggggtc taccggcagg
    27121 ctggacatct cccgcccgct ggagagccgg atcgacgagt acctcgaccg gaagttcgac
    27181 atgctcatcg aggaatggtc gctcatccgc cgttcccagg ccgagcagtt cagggatgaa
    27241 aagatgccgc tccttgcaaa agacgaggag agaatggcag cgctcaaggc tttcgaaaag
    27301 gatttcggcg aagaattgac aaggctggag gagaggattg aggctctgga aaagcagatc
    27361 cccaggtagt cgtccggaaa aaaagaagga agaagacttc atctcccgga tcaggaagga
    27421 tatccagaga gtgaggagac agggggattc ccccacgcgc gaccctgcca gtttctcccg
    27481 ctactcctgc gacctgtgca acgacacctt ccccaaaaaa gacctaaggc aatgtgccct
    27541 ctgcgggagg tgggcctgtg cgtcctgctg gacggaaaag tactatgcat gcaaggcatg
    27601 caacgggatc attaccctcc acctcacaac ggacaagccg ggtgagtgaa taacctcttt
    27661 ttaccccctt cgctattcca ggcgggacat cagcgtgcat ttgtccggcc accaacagtt
    27721 ccggattgcc cgataaaaaa gaaggaatgt gccttttcaa tgaattgatt taaaaaaaca
    27781 gcctgagtag cgtttatttt catggatgag ggcggagcaa tcttttttcc ggcgatgcgg
    27841 ggggtgtgca cccccctccc gattgtctct cgcaacacgc tcacattggt acagagaact
    27901 tttttccctg aagttccggt gaaaataacg gttcctgcat ttctccggat agatcctttc
    27961 ccccgggaac catgtgccgg agatggttca gaagaagacg tggtggatat tctcggcaac
    28021 gagtgtcacc gtgaggacga gcccggaagc gatcacgaaa cctgccgtcg tgaagatgac
    28081 agtggggacc ttttgccatc ccaggatcca ggcgatcacg ggagtgccgt agagcccgat
    28141 cccgggtatc cacgcgatga agatgcagga gatggcgccg tacgagcgga tcgacgggtg
    28201 tttctccatt ctctccccga ctttcctgat ccaccgtgca acacgttccg atgtcaggga
    28261 gagtgcgtcg cagacctcga ggatgcacgt caccacaccg actgcaaagg atgccatcag
    28321 gacgatgatg accgggtcag ccagcccgag gggatggccg aggggtgggg ctgcgccctg
    28381 caggataaat gcggatgcga tgagggggag gatcctgctc tccggtatcc cgaggacggc
    28441 accgatgagg agagggacca ccagtacgaa ggtgaaaagg aagagaatcg cccgcgagag
    28501 ctccaccagc acacgcacgt gggaccggag ccagggaaac atggtgacag gttggcaggt
    28561 atctctgata tggtttgccc atgcaacgga aaatccccgg cggaaaaaat acccggggat
    28621 cgcacggtgc atgtcaagga agggcaggaa aacagaaaac cggtgaggga ttccgacaga
    28681 aaataaccgt gcaggttctt attgcccgtt tttgtcacag gagcccgagg aaatttttca
    28741 ggaggcagag gccgcgtgaa ccactcttct cggggtgaaa ctggactccg aagacatacc
    28801 gttcgtccca tatcgaagac gcaaacggga ggatgtattc tgtctgggca agggtatacc
    28861 gatctttcgt atcggcatag taggaatgga caaaatacat gtaatcgccg ggccgtatcc
    28921 cctcgaagag aggattatcc tgccgtaccg aggagagcga gttccacccc atgtggggta
    28981 ccttgaatcc gctgacccgc gggaaccggc gcacggtccc gggaacgagc gcgagccccc
    29041 tgtgcagtcc ctgctcctcg ctccattcga gcatcatctg catccccagg catatcccga
    29101 gcagcgggac cgaccgtgat gcttcgagga tgacgatccg gagttctcca agctgctcca
    29161 tgccgtcgcg gaacgccccg actcccggca gtacgatccc gtcggcagaa gcaacgtctg
    29221 ccgggtccgt ggtgatgacc ggtcttcccc cggctttttc gaggcccctt gagaccgacc
    29281 gcaagtttcc aaggccgtaa tcaacaattg taatcttctt caccggaacc accccggatc
    29341 cgccaccctg cgtcctccac ccaggagtcg gggagactgt tggctttctg ccactccttc
    29401 agcctcgtat cccacgtctc ccagagggcc gggtagcggg agatgacgtg gcggatgacg
    29461 gcaaggtcgc tcgaagggca catgaaacac ccaatcctgt cgacaccctg ctcgtaaagc
    29521 ctgttatagg gcgctttctc ccggaagagg tacagccaga catgcagggc cgtccagtgg
    29581 tggatgggtg ccgccgagac ctgggccggg atgtgcgggt tcctccacac gcggtggctt
    29641 gccatcctcc gggacgattc aaacttccgc tgcccgataa aggagaggca ttcgccccac
    29701 gtgttcctga tgaccctgtc cacaggtgtc agttttgccg cccggcaaca ccaccggaag
    29761 tcgcgtgcag gtggccccct ggtcgaaaag gcttcccaga acgcctcgct gccctgggcc
    29821 acggtcacgg ggaggccata gcgtgctgcc acttcccgga cgttgtcgta tgtctcggga
    29881 aattcaagcc ccgtgtctgc aaagaggagt gggacttttc cgagggcttt cgtaacgagg
    29941 atcagtgtca cgaggctgtc ctttccaccc gaataggaga cgttttggga gaaaccctcg
    30001 tggccctgcc ccacgttccg tatgaaaccg attgcctcct cctcgtgttc ggagagaggt
    30061 ccggcgttcg ctgccacggc atcatcccat gttgccttcc cgggcacgca gacggatgca
    30121 aatgtccgcc gggtcctgac gacgagtccc cgttccatcg atcctgcagc atccgcgtcc
    30181 acacgtgccc gtccgacggc aatgcactct cccttttcgt caagtacaaa gacttcgtcg
    30241 cccttcctga ccgagggctc gatggtaacg aggcccgggg caagcaggct tgccgaccgg
    30301 tccctgatcg ccgctgctgc cccggcgtca gcgaccaccc acttcctggg cggggcggac
    30361 agtccgaaag cttccttccg cgggatcgct tcccatcgcc cttcctccgg gatgtagcgt
    30421 atcgcgccga ccaccccgcc ccccacgatc acctcttcca tgcggtccgt gtcggggacc
    30481 ttgttgagga gggcgaggtg cccgtccggg atgaggggag acccaaagtg atcggaatag
    30541 accttgttca caaggtcaac gtcggcaggg aatgcaggtc gcggatcacc gggtggcgtg
    30601 agcatgaccc tccgtgtcac tccaccgcac cgcgaacacc cgcgggagag gacgggtgtg
    30661 tggcacgtgt cgcaccacca gagcattccc cggaacgaga ggggcgacgg catcgctcct
    30721 tagacgtgtg ccgatctttc cataaatatc cacgggtacg tgcgtctcct tccgggacat
    30781 ttccgggaaa agacccggta cagtgacatg ccggaatgga cgtcaccttc tgccggcaaa
    30841 agcagaataa tcacaccatt tgccggaaga gcggattctt tccggtatct tcattatcaa
    30901 tcatgatgta ttgttcccgc gaaagaatgt cgggtggccc ccggtggaac gcggggacaa
    30961 acaggctccc ggcatccaag actcctccgt gattcccatg acgatcaagg cacacacagg
    31021 accaaaacag catcggtgcg gagggcccgg atgatagcct accttgtcac cttcatcatg
    31081 gccttcctcc tctacctcgt cttttcagcc gggagcggga cactctggct gtggtcgccc
    31141 tctgaacttc tggcaggatt cctcctctcg ctcctcacgg cagcagtcgc aggaaaggtt
    31201 ctctgccggg gaaaggacta ccggatggca aaccctgtcc gcctgctcat cctgcctgtc
    31261 tacattctcg ggcctttttt tatcgaggtg acacgggcca acctcgacgt ggcatacagg
    31321 gtcatcacgg gaaagatccg gccgggcatc atcagggtgc cgtccggcat gaagacggac
    31381 ttcggtgcct ttctcctggc caattccatc accctcaccc ccgggacgat aacggttgac
    31441 atcagcgagg agacaaacga cctcttcgtc cataacatca acgtgcccgc gggctgggag
    31501 acacgcgaca cggtggaagc gcgggagttg ttcgggcttg caaacatccc ggcatggatc
    31561 cggaggattg cagaatgact gctccgttcg atattgctgt cttcatcctc ctcgtgctcg
    31621 tctgcctcgc cctcgtccgg ctcgtcctcg ggccgaccat cgccgaccgt gccgttgccg
    31681 tcgataccgt caataccctc gttgtcgctg ccctcatcgt tctcggcgtg gtctaccagc
    31741 agatcatctt catcgatgtc gcaatcgtgt atgcactcct ctccttcgtg agcacgctct
    31801 acgttgcaaa gtacatcggg ggtgaactgt gatcgccgac gtcctggtcg ttgcatgcct
    31861 cgtcatcggc actgccttca actgcctcgg gatcatcggt ctcctgcggt tccccgatgt
    31921 ttacacgagg atgcatgcaa cgacaaagat gacgacgttc gggtccgtct tcacggctct
    31981 ttccgtcatc atttatggtg ccgcccagtt catcggaacg ggcgacgggc agtatgtcac
    32041 tttggccgtg cacaccctcc ttgcagcact cgcgcttgcg gtcacgaacg caatcgggtc
    32101 ccatgccatc gcgcgcggtg cgcaccggtc agggatcaag ccggcacagg ctgtggtcga
    32161 ccgcctcggg gaggtgcccc catgatcgag ttactcatcc aggttgcggt catcggcggg
    32221 ctgatcgctt ctgccatcct ggtctattcc ttccgggacc tgcttgccgc tgcacttgcc
    32281 gggggattct tctcgttcct cgtctccctc gagttctata tcctgcaggc tcccgacgtc
    32341 gcgatctcgc aggcagcgat cggtgccgga ctgacgacgg caatcttcat catcgcgatc
    32401 cggtccacga cccggttcga ggaggagacg ccatgaaaaa ggtcctcgtt gccgccatat
    32461 tcctcgtctg ggcagcaggt ctgtgtgcca tacccctctt cctctcgttc gggaaccctg
    32521 ctgcaacaga catggacacg tatttcatca ggaccgggca ggcagctgcc gccgcaaaca
    32581 acatcgtcac atccgtcgtg ttcgacttca gggggttcga taccctcggg gagtccgtgg
    32641 tgctctttac agccgtgaca ggcgtcgcac tcatgttccg ggcaaggaag gagggtgagg
    32701 accatgagga tgagtaagat cgtgcggacc ggcgcatgta tcctctaccc gctcatcacc
    32761 atcttcgggc tctacgtggt cgttcacggc cacctgacac cgggcggggg tttccagggc
    32821 ggggcggtca tcgcgactgc cgcagccctc gtcctcgtcg cgttctcgca cgcggatatc
    32881 gccggtatgg tcaggaaaac cgtcttctcg gcgcaggaat cgctcggcct cctcctgttc
    32941 atcggtgccg ggatactggg cctccttgca ggagcgccgt tctttgccaa catccttgcc
    33001 aacagcggtc tcctcttcgg gctggcggtc cccccgggat caaaccccgg cgacctgaac
    33061 accgcgggtg tcatcccgat catgaacatc gcagtcgggg tggaggtctg gggtggtctt
    33121 gcgattatcc tcatgtacct gttctccgcg accgggggtg agggggcatg accccggtgc
    33181 tttacaatct cccgttcgtg gccgttgtcg tgctcaccat catcggcctt gccacgatcg
    33241 tcctcaaacg aaacctcatc aagatattcc tcggcatcac gatcctcgaa tctgcagtca
    33301 acctcttcct cgtctcgctc gggtaccggg agggcggcat tgcacctatc tacaccaacg
    33361 caccggacag gctgatggtg ctcccgacgc cccaggccct gacgctgaca tcgatcgtta
    33421 tcggggttgc cacaactgcc ctcctcctct cgtttgccat cgtcatctgg aaaaaatacg
    33481 ggagcatcga gatcgggttc ctccggaggc tgaaagaatg atccccccgt tcgtcattga
    33541 aaactcgcct gccctgatgg tcatcgtgcc gttcgtcgca gcgttcatcg cgccgttttc
    33601 gggcagggtt gcacccgccc tccgggcact ggtcgtcggg ggagcaatgg ccatcacgtc
    33661 cgcgatcacg ctcctcctcg cgtccgacgt gtacgcgcac ggcacgcggc tctacgtgtt
    33721 cggggcacag gcggcaacgc tggcagtgcc cccggactcg ggcggcatcc ccgtccggat
    33781 catgttcacc gtggacccga tgagcgccct catgctcgtg atcaccgcca tttcggcgtt
    33841 tgcagtcgtc ctctactcgc tgacaagcga gaggcaccac tcgggcctcg gcagttacta
    33901 cacgctcttc ctcctgatgg ttaccgggat cctcgggatg gtctcgacag gcgacatctt
    33961 caacttcttc gtcttcctcg agatcctttc cattgcgtcc gcgggcctga ttgcattccg
    34021 catcgacggg ggtgtcgccg tggaagcggc catcaagtac ttcgtcctga gcaccatcgg
    34081 tgcactcgcc atcctctttg caatcggcat ctattacggg gagtacaacg ccctgaacat
    34141 ggccctcatc gcccagagga tgcagtttac actcctcgac cagctcgccc tcgtcctgat
    34201 catcgctgcc ctcgccatga agtgcggggc tgtccccatg cacttctgga ctcccgacgc
    34261 ctattcgatg gcgccatcgt cgatcacggc cctccttgtc gttgcaagcc aggcaagcct
    34321 ttacgggctg ttccggacgg tgttttccct ctataacatc accctgaacg ccgcctgcgt
    34381 cggctggctg atcatcatcc tcggtgtcct ctcgatggtt gtgggagtga cgatggcgat
    34441 cccccagaag aacgtgaaac gcctgatggc ctaccacgcc atctcgcaga cggggtacat
    34501 gctcctcggc gtgggagtcg ggcttgctgt gctcggcaac cagccactcc tggatgcctt
    34561 cgggtacatg gccatggagg ggggaatctt ccacatcatc aaccatgcca tgtacaaggg
    34621 gctgctcttc ctgacggccg gagcgatttt cttccggatc gggacctatg acctgaacaa
    34681 aatgggaggg cttgggcatt ccatgaagtg gaccatgatc tttttcatca ttggtgcgct
    34741 cgcgattgcc gggatacccc cctttaacgg gtttgcctcg aaactcatga tatacgagtc
    34801 agtgtttgct ttcaatcccg tcctttccgt gattgccatg gtggtgagta tcctgaccct
    34861 tgcctcgttc gtcaaggtgt tccactcgat cttcatgggt cccgtcctgc ccgagtataa
    34921 ggatgtcagg gaagtgcccc gcccgatgct cgccgggatg ggtatcctcg ccctcgtggt
    34981 catcctgttc ggcatcttcc cctctctcgt ggtggagacc ctcgttgcgc ctgcagcaca
    35041 cgcgcttgcg gaccagggga tgtatatcgc cgccgttatc ggcgggggag tgtgagacga
    35101 tggacatgct ctttaccctc gataccggtg ccggcttctg gaaccctgtc ctctggatcc
    35161 tcggggccgc tgtcgccggc gtcatcgccc tcatcctcta ttccctcggt gaaaagggct
    35221 acaggaaagg gaccgcacag gaagacccct tcatatcggg gaacccggaa ccggagaagg
    35281 gactcgtcca cgtccgctcc ggaaacctct actgggggtt cctcgatgcg atgaacgggt
    35341 attaccggcg gctcgtcccc ctgcacaccg gggatctcca tgactacgtc ctctggtaca
    35401 tgggaatgac ggccctgttc ctcgtcgtgg tggtggtctt ccgatgaaac tgaatgcact
    35461 gttcaaccgg tcgctgtggg tctaccactt caactccggg tcctgcaacg ggtgcgagat
    35521 cgagatcgtg gccaccctga caccccggta cgatcccgag cggttcggga tcaggctcgt
    35581 cggcagcccg cggcatgcag acgtcatgct cgtgaccggg cctgtcgtcc acaggatgaa
    35641 agacaggctc ctccgggtct accagcagat tcccgacccg aaaatcgtga tgtgcatcgg
    35701 gacgtgcggg atctccggcg gtgtcttcta cgaatcgtac aacctggacg gtcccgtgga
    35761 cgaggtgatc cctgtcgatg tctacgtccc gggctgcccg ccgcggcccg aagcaatcat
    35821 ccacggcgtc gtgaaagcac tggaaaaact ggaacggctc cagggggtgg aggcatgaag
    35881 gaaggaaccc ttaccccgga agaggtcatg gctcacctga cctcgcgcct ttcaggaggc
    35941 atcagggaca cgtccatcag gaagtgggag cagggcagaa agaaggtgcc gcactatacc
    36001 ctctgggtcg atctcgaacg cgacttcctc aaacctgcaa tcagggcact gatggagatc
    36061 cagttccccc acctctccgt gatcgcgggg gctgacctcg gcgatgcaat ccgcctcctc
    36121 tacatcttct ccgtccagta cggaagcccg aagagcgagt acatggtcac gttcgcgatc
    36181 gcgctgccga aatccgacct gacggtcccg accatctcgg acctcatacc gggtgccgtc
    36241 ttttcggaga gggagaagca ggagttcttc ggcatacggg tgacgggtat ccctgacagc
    36301 aggcgcctct tcctgcccga agatttcccc gaaggtgtct ttccatggcg caaggacgaa
    36361 acgggcgtgc cggagggaat ggtcagggaa ctctgggaat cgaagcggcc caaagaccgg
    36421 cctgccccgc cggtcaaaga gaagggaccc ggtacggcgg gcggtgagac ccctgccgcg
    36481 tctgcaccgg ccgggggatc ggcaaaggag ggagagagat gagtggcgag tcgaagaaag
    36541 caccataccg ggtacccata ggcccgaacc accctgctct caaggaaccc gtgatgttca
    36601 ccttcgagct ggagggagag gtcgtcaggg acgtcgattt cgcccccgga cagacacaca
    36661 gggggatcga gtggatgggg atgcgccgga acccggtcca gatcgtccac ctcacggaca
    36721 ggatatgcgg gatatgcggg gtcgtccact cgctctcctt ctccctggcc gtcgaacaga
    36781 tcgccggcat cgaggtcccg gagagagcgg actacatccg gacgatcgtg cacgagttcg
    36841 agcgcatcca gtcgcacctc ctctgggcgg gtgttgcagc ccacgaactc gggtttgact
    36901 ctctcctcca ccttacatgg agggttcggg aggaggcgat ggacgtcatc gagaacctga
    36961 caggaaaccg cgtcaactac ggtatcgtac aggtcggggg agtcaggagg gatatcgtgc
    37021 cggaacagca cgcaatcatc gagaagtgcc ttgccaccta cgaggggctg ctcgacaccc
    37081 tcctctcctt tttcctggac gacaggacca tccggatgcg gtgccgcgac gtcggtgtcc
    37141 tctcccgcaa agatgcactc gagctgtgca ctgtcggccc gacggcacgg gcatccgggg
    37201 tcaacgttga cctccgccag gactacccgt acgctgcata cggagacctc gacgtcaaag
    37261 ccgtgctgcc cgaccggtac ctgggcgaga cccacggcga tgtgtacgac aggatcgtcg
    37321 tgcggctgct cgaggtcggc cagtcctgcc agatcatccg gcagtgcctc tcggagatgc
    37381 cggcagggcc gatcacggcc gaggagaagc tggtcaagct ccttgcgacg tgtaaaaagg
    37441 cgacggggga gggtatcggg agggtcgagg cgccccgggg cgagtgcctc cactacgtca
    37501 ggatggaggg gaaggactcg cccgcctcgt ggaaggtcaa ggcatcgtcc tactcgaacc
    37561 tgatgtcctg gatacccatg ctccgcggat cgcagattgc cgatattccc attatcgtgg
    37621 cctccattga cccgtgcctc tcctgcaccg acagggttgc catcgtccag gacagccgga
    37681 ggtccattct ttccaaggat gacctccacc gtctctccgt ggagaagacg aggaggttgc
    37741 agggatgacc ccggcagaga tcgccctcct ggccgcatgg tgtgccgccc tctccctctt
    37801 tgcactcgca gggggtctcc tcctctcggg aatcgacagg aagcttgcgg cacacatgca
    37861 ggcccggatc gggcctccca tcaggcagcc tttcatcgac acggtcaagc tcctccagaa
    37921 ggataccgtg gtcccggcca atgccatccc ctggctcttt aacgctgcac ccgtcgttgc
    37981 actcgtctcg agtgtactcg tcctcttcta cataccggtc ggaagcacga tgcccgtgct
    38041 cggggcttac ggtgacctcg tcctcgtgat gtacctcctg acggttcctg ccctcgcact
    38101 cgttgcgggt gggtttgcat ccggatcacc gtatgcgacc gtcggggcac agcgcgagat
    38161 ggtgaccatg atcgcgtacg agttcccgct ggcaatcgtt gtcatcggcg ttgcatggag
    38221 gctcggtgca gcaggtatct cccacccgtt tgcactccag tccattgctg caaacccggt
    38281 atggtctgtc acaggaccgc tcgggctcgc cggggttttc atcctcctcg tcgtgcttgc
    38341 tgccatcact cccgccgaac tctcccgtat cccgttcgat acgcaggagg ccgagaccga
    38401 gcttgcaggc ggcctgctgg tcgagtattc cggcaggaac ctcgcgatgt tctccctggc
    38461 ccaggctgca aagacactcg tccttgccgc gatcatcgtg gctgtcttct tcccctggac
    38521 actctcctcg ttcctcgcga tgcctcccgt cgttgccctg gctgccgacc tcctcttctt
    38581 cctcctcaag gcagtcctcg tcctcttctt tgccgtcacc ctcgtccggg tcgcgatggc
    38641 gcgattccgg atcaacgagc ttgtctcgtt ctactgggtc tacctctctg tcatcgggct
    38701 tgccggactc ctcctcctga tggccgacgt tattgcagga cccctcgcgg gggtggggat
    38761 atgagggcgc tgccgctcgt ccccgaactc gtgcgccagc tcttccggag acctgccacc
    38821 aaccggttcc ctgccaagta cctcccgcca tccatccggg ccttcctccg ggacgtgcag
    38881 gccggccggg cagccgtaaa ccctccggtc cccacaccgc cacggttccg gggaaagatt
    38941 gcgtatgaca gggactcctg catcgggtgc acgctctgcg tgaaagtctg tcctgcccat
    39001 gcgatcgaat tcatcccgga tataaagaag atcagggtct gggtcgacca gtgcatcttc
    39061 tgttcccagt gcacgagcat ctgcccgaag agctgcctct ccatgacgga tgcattcctc
    39121 ctcgccggcg aggacaggta tgccgaagac ctgatcgtgg agtaggaaaa aagccacttt
    39181 ttttgactga gaatcacttc gcctttttca agccgtatgc ctgaccaaac ggcagccatg
    39241 ggtggttcct gtggaaaatt gctgcgtttt ttcattctga atctctcagc ccggatgaaa
    39301 tacgtctatt tttttcaaaa aaaaagaggc agaagaagtc attggtacac cgggggttgc
    39361 agcgggaaaa ttccggtccc tctaaagcgg tccctgtgcc cccgttaccg gaacaccggg
    39421 atcctgtccg gttctccccg ttccaggtac ccgatgagcc tgtcagcccc ttcccggacg
    39481 ggaggggaga gcccctcccc tgtctccaca acgaggggct ggattccgat aatgactatc
    39541 cgtccggccg aatgtgcaag gtaatccacg atgacgtcga gcggaagctg gtgcgtcccg
    39601 aaggagacgt cccgcagacg ctcttttgga accacgcaga actccccggg cgacctcccc
    39661 atctctgccg cgtcgacgat gacgaggagg ccggggtgct ctctcctgac gatccccgtg
    39721 aaattttccg gaacggtccc gcagtcaagc gacatccagc cctgccggcg gaagcccgcc
    39781 gcgacgtagt ttcccacccc gtcgtcccgg cgaaggggat ttccgacacc aaggaggata
    39841 ttgaccattg cgtctcttcc ccggaccaaa tccttggtct cacaagccca tggtcgcaaa
    39901 aagggcaagg atgacgagga tcatgatggc gactgcacag gcaaccggca tgggagagac
    39961 cccgaggagc tggggaatgg tctctgccgg aaacttcccg cggttcagga cagatcgttc
    40021 gaggaccggg tagagccggg caaagatacc tgcaccgatc acgatccctg ccatgccgac
    40081 tgctgcatcg agtgctcccg atccgagtgc cccggcggcc gtcccgggac agtacccgag
    40141 gaccgcaaaa ccgacaccga agatgagacc gccgatgaca gtcgagccaa ccgagcctgc
    40201 ccggacgtgg agacggacca gccccgcagc cttcatggca tggaccccga ccatcccgac
    40261 gaggatggca gagagcatca ccttgacaac ggtgaagtcg gtgagcagga gctgcccgat
    40321 gatcacgtcg tacagcgtca ctcctccctt ctggaggaga aaaccgaata cagtgccgaa
    40381 aacgagcccg aggagcgcct gcagagactt gttctgcctt atcccttcga atggcatggc
    40441 gtttccacct cacaggaacc gaaaaccaaa gaggagtcct gccgcaagga ttcccccggc
    40501 aaagaagcag atcaccgcga cccagctcgc aagcgagagc tggagcgtac cggagatacc
    40561 gtggcccgac gtgcacccgc cggcccagcg ggcaccgata cccatgatga ttccgcctgc
    40621 gagtgcaaca gcgaaacgga agagggtgtc agccccgaaa gtttccgcaa acagcggggg
    40681 gacggcagaa agggcaaacg tccccgcggt atacgccgag atgaacccgc ctgcaatcac
    40741 cccgatgatg atggtccact gccagtccgc ttccggggtc acctggcggt agtacggcat
    40801 cgatgcaaca ttcttccggg atactgcctt ctctatcatg cctgccgtct ttgcgtatgc
    40861 agtagacgct ccgagcggcc ggtcggagaa gagaaatgtc atccagatca ggatgccaat
    40921 ccctgcaccg acgacatagg gcgaccaggt cgcagataat aaccagtcgg acatcgggat
    40981 tccctgatca ctaggaggag cattccaccc tgataagccc tcccatcagg atacgaaacc
    41041 tgccttctgg tacgccgaaa atcccccggc gaggttggac accgttttga atcccttcat
    41101 cttcaggata ctcgccgcga tgctcgcccg ctgacccccc ctgcacatga cgatggtatg
    41161 catcccgggg tcaagctcga cataccggga acggagatcg tgccacggga tatggactga
    41221 acctttcacg gaagcggcag tccgctcctc ccgcgacctg acgtcgacaa ggaccgcatc
    41281 acctttttcg aggagtgcat gcgcatcggc cggtgcaatg accgggaccc ggtcgacggg
    41341 gagaccggca gcactccagg ggagcatccc gccatcgagg taccctgcta tactgtcgaa
    41401 tcccacgcgc cttaactgga gtgcggcttc catggcctgt tccctgttct cggcgacgag
    41461 acagatatcc tgcccggggg gaaggatcca tcctgcctgg gtggcgaagt tcccggaaag
    41521 gtcgatgtgc cacgatcctg ggatgtggag accggaaaac gcgggatagc tccgcacgtc
    41581 caggagcacg gccccgcctc cgcgggcacg ctggctgaac ggctccgggc caagcgggag
    41641 aggttcaggg agattgcgca tcagggcagg tcctttccgg tttatctccg agcagcggga
    41701 aaaatggtcg ggggcagcag gcatgccgga cgtgagcgcc cggacaaact cctcccgatc
    41761 cctgatccgg agcgcgtagt tgtatttcct ttcgtatcca atcgtgctcg tcctctttgc
    41821 agccatcgcc ctgccacaga gcgagcccat gccgtgcgcg ggatacagct cgcactcgtc
    41881 cgggagcgtg agtatcttgg cctgcaggtt cccgaagagt gctgtggcaa gttcctctgc
    41941 ccggccggga aagagatcgg ggcggccgac gtcgccgaca aagagtgtgt cacccgagaa
    42001 gagcgcgacc ggcgtttttc cccgggacaa gtcggttgcc acgtagcaga catgctccgg
    42061 ggtatgtcct gcagtttcga tgacccggaa cgtcatatcc tcgatctgta tctcgtcgcc
    42121 ttcgacgact ccttcatggg gaaaagagca gtgtcctgcc cggggtgcgt atattccggc
    42181 gccggtttca ttggccaggt cgaggtggcc cgatacgaaa tctgcatgga ggtgtgtctc
    42241 gaggatgtgg gtgatggaaa gacccatgct gcgtgcaaaa gtgatgtacc tcgcggtatc
    42301 gcggctcggg tcaatgaccg cacatgctct gttcccggca acgatgtagg aactgtgggc
    42361 tattccgggg acgaagaact gccggattat cataccgggt tatagaacaa ggagatacat
    42421 gagggtaacg gcaatggcaa tgaacatgac cgacatgatg cttcctgccc tgatatagtc
    42481 ccacgggcgg tatccccccg gccccatcag gagtgcattg acctggtgcg tggggagtat
    42541 gaagctgttc tgggcacaga ctgccacgag gagggcaagg gcccttggat caacacccat
    42601 gtcctgcccc gtgaccatca cgagagggac gaggaggatc gttgcagcaa cgttcgagat
    42661 gacgagggag aggcaggttg caatcgctgc gacgacgagc atgaccacga gcgggtgtgt
    42721 gccggaaagc actcccgcaa gcgatcctgc gaggagggcg gctgccccgg tcttctcaac
    42781 ggctattccc agggggatca gtcccccgat gaggacgatg gtcttccagt cgatcgccct
    42841 gtacacgtca gcaggaccga gtacccggga aaggaccatg gccaacgcac ccgtgagaag
    42901 tgcaagggag agggggactc cggtcagcgt gagtgcaagg gaagaagcga agatcagcac
    42961 ggcgaggaag cccttccggt aatgcacggg gtctccctcc ggctgggaaa tcagctgcag
    43021 gtcggtgtgc cgtgcaagaa ccctgaggtt ctcccaggat ccgaacgcaa cgatgatgtc
    43081 gcctgcagca aggggcatgt cagagaagtc agcccgggtt tcggtctccc ccctcacgtg
    43141 gacgatgggt tcgatggcaa aagtcttgcg gaacatgatc tcccgcggtg tctttccgat
    43201 gatggatgca cgtggcctga caacgagttc cgcaaacccg tatccccctc cggtgagaat
    43261 ttcagcgaaa ctgcccgttt ccccggcagg gatacatccc gtttttctgg caaactgctc
    43321 gaaaccttcc tttgggccga ggattgcgag ttcctggccg ggctcgaacc ggaaccagcg
    43381 ggagggcgct acctggatgt cgtctccatc ccggattgca aggagaaaaa gaccgtgcgg
    43441 gttccccgaa aagacctcct cacgggtctt tccggacagg ggggaggatt cactgatccg
    43501 gcaggtcagg atgggctggt ttatattcca gatctccggg acggatggcc gggggacttc
    43561 tccccctgta ccggggatga cccggtgtcc tgcaagggag aagagtgcga ctcccgccag
    43621 gagaaggaca atcccgatgg gagtgaccgc aaagagggag aagggttctg cccctccctg
    43681 gcggagcagg tcattgagga ctattaaggg tcctgaccca atcatcgtca ctgttccccc
    43741 gaggatcgct gcaaacccaa tcggcatcat cagacgggaa acgggaatgc ccgtccgcct
    43801 cgcgatcctg cctgctgccg ggaggaagat tgctgctgca ccgacgttat ggatgactga
    43861 tgacaggagg ccgactgtca gggaagtcgc ggcaacaacc cgctgctcgg ctgccccggc
    43921 ataacggacg atgaaggcgg cgagacgtga tgtgacaccc gcacgctcga ggccggttcc
    43981 caggaccatg acggctgcca tggcaacgac ggcatttgag gaaaaaccgg aaattgcctc
    44041 ctgcggcgtg acaaggccgg accacgcaac cgcaaggcac gcgaggattg caacgaggtc
    44101 cacccgtatc aggtcgcttg cgaacaggac gagcgtcccg acaacgatgg ccgacacgag
    44161 gaggatctgg gtgtccatct gccttcacag gcaggtgtgg gcaaaggctg ccaaaaaggt
    44221 tcccccagcg tcacggaaaa gagggcggga attgaaaccg ggatatccgg aacaagattc
    44281 cagcaatcat tgcaccgtgt ccctccacct gcgggccttg caggggtcgt ccgttgcaaa
    44341 accgtcgacc cccatcccgc gggcccggtc ccattcggca gtcgaaccga gtgtccatgg
    44401 tatcacgcgc atgccccgtg cgtggacctc ttcaacggct tcccgggtga gggtatcgaa
    44461 cttcggcagg tatacccgga acggaggatc ttcactcttc cgtggagtcg ggggcacggg
    44521 ctgggtgtgg atgagcccga gggggatatc gggcatgacg tcatggacca tcgcaaggga
    44581 tgcgcggtgg aacgagacca cgaggagggg tccccccgcc acccggtcga ggacctcgca
    44641 cacttcaagt tcactcccgg gctcctttat ctctacgcag aggcctgttt ttcccccgat
    44701 gagcaggcat acctcttcga gtgtcgggac gggctcgcct ttccctgcat cgaggagcct
    44761 gagatcggca gccgaaaact ctgcgacgcg cccgttcccg ttggtcgtcc tgtcgacggt
    44821 cgggtcatgc atgaggacag ggacatggtc ccgggagagc cgcacgtcca cttccacgta
    44881 atcggcacat tccattccga tgcggatggc cgccagggta ttttcgggtg ctgcggcagc
    44941 cgcacccctg tgaccgatga tctccattga atagcgtgtt ctggtttcac ggagagataa
    45001 aatgcgatga tcggggggtg caggccgccg atcataccgg agatacatgg gcacattttt
    45061 tggttttcgg ggaagagagc tcatgcaacg cattcccggg tcacgtgttt tccatggacg
    45121 ttccactgaa gacctccctg ttcgagatat gtccggcaaa gggggtccca ctctccgaaa
    45181 ggctcatcag aatcgccatt cccttcgtga tcggggggtt ctacatcctc ctctgctttc
    45241 tcttcctgcc ctccgacagt gcccttttgc tcggcggcct gatgcttggg tacctcgttc
    45301 ccccggcagg aaaggaaagc atcgtcccgc tgggaattgc ccttggcttt ccctggtggc
    45361 tgatagcttt ctcgatcggc ttaatggacg tgctcgcagg gatattcatg gccttaaact
    45421 gcgacgtcgc ggtgaagatc cccctcctcg gccgctggat ccggcggttc ctcgaaaagg
    45481 gcaatgactt tgtgcgcaaa cgtccctggc tcgagaagtt ctacttctcc ggcgtcgtcc
    45541 tcttcgtgat gtttcccctc cagggaagcg gcggtatcgg tggttcgctc gtaggctgga
    45601 tgatcgggct gtcccccggc cgcacgctcc ttgccattac catcggggca ttcctcgggt
    45661 gcacgctggt tgccatcggt tcccaggcaa tcagggacct cctcctctcg aaccccgtgg
    45721 caggaattct cgccctcgtc gcagtcattg caaccctcgt tatctcctat tccttctaca
    45781 ggtggaagat caggtgagtg acggatcttt tttatcattc atttcccatg tccatgctgg
    45841 agggatgatc ccatgagcct cgtcattgca ttctgtggca gagatcgctc cttcatggcc
    45901 ggggacagga gggagatagt ctttcgggga gatgacctgc gcacgaggac actggaagac
    45961 gaactctatt ccggacggat acggagcagg gatgctctcc acgagagggc ccgggaactc
    46021 ggaatcgatc tctggatcca tgacgacagg tgcaaggcct gggaggagga cgggattctc
    46081 atcggacagg tgaacgagag ggacgggctt tccacgcgtt cgcggaggct gtgtgtctcc
    46141 tgcgggaact acgttatcac ggaggtgctg gaaggcatca aaagggaggt cacacgggga
    46201 tgcgcaagcc gcttcattgt ccttggcaac aaaacgacgc aggaaatagc acaccgctgc
    46261 attcgctccc actggagtga taccgggggg actcctgccg atgccctgcg aatcatcatc
    46321 cttgccatgg aagaggctgc atccctgacc ccctcggtct ccggaaccta taccctcgtc
    46381 cagacaacag caaagacagt actgcctccc tagggaaaaa cgcagaggtt tcttgttttt
    46441 cccatcttct ttttgtcttt tgcgattccg ggtgggcaat gtgacacgga ggggagagag
    46501 gtccgcctac cctgaaggtg aggtttatct ccgaccgcgg gaaaaactgg acaggaaaaa
    46561 acctggttac ataaaaaatg aacccgaaag tcaggttaat catcgaagag acttttccga
    46621 aactcatcga gaggcatatc cggacacgcc cggcagttga ggcaacccaa aagagcctgg
    46681 actcgtaccg caaaatgggg tacgctgcag tcaggaatct ttctcccgaa gaacgcgacc
    46741 tcaacgagaa ggccctcgat accgcgtatg ctgcctccat gcaacagtta catgatttcc
    46801 atgcccgcga aaagtcgcac tccgggacca tggaagggac agagaaagaa acgatttgaa
    46861 ccacggattt tccccgtgat gaccatattc tttcctgtct ggtcatttca tccttcctac
    46921 gtttttcaca gggaagaagc aaaaatccta taaacttttt catcccagct ctttctatgt
    46981 catgctatat catagcatgg tgattctcca tgagaaccga ttgcattatt tacacgatac
    47041 ttggtttgct cctgatcgcg ctgctcctcg gggccggctg tacgcagacg ccgtccgcaa
    47101 cagggccctc cgagataaaa atcggagttg tcgcctccat gacggggcct gcaagcacaa
    47161 ccggaaagga catctggcag tctgcagaac ttgctgccaa cgagatcaat gccaaaggag
    47221 gcgttcccgt cagggaatta gggcgttccc tgcctgtccg gctgatccag ggggacgacg
    47281 aatcaacccg tgaagggggc atgaaggcag tgacaaagct catcacgcag gacgaggtca
    47341 acgtcctcgt gggaggttac tcgagcgcgg tcgtttctgc acaccagtcg atcgttgccg
    47401 acaacaaggt cccgtacatc atctcgggtg cgtccagcag tgcggtctcc cggaggacgg
    47461 acctcgatac gagttacatg ttcttccaca ggccaaacac ggatgactct gccgaggcga
    47521 gcatccagtt cctgacagat gtcttccggc cggcaatcaa cgaaaaattc gggttttcca
    47581 acgaccggaa actccgcgtc gccgtcatct accaggacag cccgtttgga aagggccagc
    47641 tcgatgccgt gaaggcactg attccggcaa agaacctccc gatcgagatc gtggcagaag
    47701 aacctttcaa gatgggtgaa tccgacttca ggacggttct cacctcggtc agggcaaaga
    47761 accccgacgt catctacgcg gtcacgttcc tcaacgaact cgttcccatg acccagcagg
    47821 cccggaggga cgttggtctc aatacggtga tcatggcgat cgagaacaac gatgaccccg
    47881 attactacag cggggtcggt gtctacggtg acggcatgat catggagagc aggttctccc
    47941 cctacgccgt ccccgcagga tcgacggagg cagcaacccg gaaattcctc tctgacttcg
    48001 acaagaagta cggcggattt gcgggcatga tgggtgcggc aacgtacgaa tcggtctatg
    48061 ttgctgccgc ggccatcgaa caggcaggca gcctcgaccg cgcaaagatc agggacgccc
    48121 ttgccaccat ccgggtgccc cagatgatgg agatcatgaa gaatgggaca atttccttct
    48181 ccccggagtt ccgggagagc aagtttgagc tgtacgtcgt gcagcttgcc atggaccaga
    48241 agtcgggaga accccggccg gtgatcgtct ggccggaaag cctcaaggca ggggagtttt
    48301 ccattccgga ctggtatacc cccggatctc cctgaatctt tattttggga cagggagagg
    48361 taatacagga tggatggcgg catcgcagta cttggccagg tcgcattctg ggggctctac
    48421 tcggggtgca tctacatcct gctcgccaca ggactcaacc tgatcttcgg ggtgatgaag
    48481 gtcgtcaact tcgcccacgg cgagttcctg atgctcggga cgtacatcac gttcttcttc
    48541 ttcgtgataa gcggcttcaa cccctacctc ctcctcttcc tgtcaatccc catcctgata
    48601 ggggccggga tcatcgtgga acgcctctgc ttccggccga tcctcgggac gggaaaactg
    48661 aacgagatat tcatcagcct cgggctgatc tacatattcc agaacggcgt cgcaatggtc
    48721 tttaccgacg agtggcgttc gatgaaaagt ccctttgcag acctgaccat agggatcggg
    48781 cccatccagc tgcccctcga ctacatcatc atcgtggtga tcaccgcgat catcctcgtt
    48841 ggcctctccg tctttctcga caggaccacg acgggaaagg cgatccgggc gtctagccag
    48901 aacaggaaag gcgcgatgct gatgggaata aacgtggagc ggatggacat gctcaccttc
    48961 gggatcggtg cgggactcgc cggggcagcc gggaccctct gggccgtgag cggccaggtc
    49021 ttcaatccct acatgggatc ggtgccggcc atcaaggggt ttgcaatcat catcctcggc
    49081 ggcctcggga gcatcccggg ggcgatcatc ggcggccttg ccatcgggat ggttgaaaac
    49141 ttcactgcat ttttcctcgg ggggtcgtgg aaggacgcga tctcgttcat cctcctgatc
    49201 gtcgtcctcc tcgtcaggcc gacggggctc tttggggagg ccggggaatg aaccttgcgc
    49261 aggtgcgaac accaaagaac ctgcttgcgg cagccatcct gatccttgca ctcgccttgc
    49321 cgttcctcgt cggccagaac ctgtacctcc tgaccgtcct cgtgctgatg ctcatcttca
    49381 tcatctattc gtccgcctgg aacttcctca ccttctccgg acagggatcg ctcgggcatg
    49441 cggcattcct cgggctcggc gggtacgcgg cctcgcttgc gaccgtccgc ctcggtctcc
    49501 ccccgctgct cacgctcgtg ctggggggct tgttctctgc cttcatcggc atcctgatcg
    49561 ggatcacgtg cgtgcgcctg cgcgagtggt tcctcgcgat ggtgacgttc ggtttcgccg
    49621 tgatcatcca gaccctcgtc gtgagccagc tcgcacccgt aacaggggga tgggatggct
    49681 ttgcagtcca aaagatcgtc cccaccacga tcccgggtta cctcgtcctc gagtactacg
    49741 ttgttttcct cattgccgtc cttgtcctgg tcctgtttta cctgcttctt cgttcccgca
    49801 tcggccttgc tcttgcggca atccgcgaga acgagaccga ggcacgggct gccggcatca
    49861 acccggtccc gttcaagctg ttcgcgttcg gcctttccgc gttcgtgagc ggtatcgcag
    49921 gcgggctcga gatcttccat ttcgggtaca tcactcccga gatcttcggg atcgacctct
    49981 cgttctggcc gatcatctac tcgattacag ggggccttgg gacactggcg ggtccggtca
    50041 tcgggacgat tgtcgtcacc cttctctggg acgggctcaa cgtgctcggt ctcacgtacg
    50101 ggcggttcat catcatcggc gtgctcctgg ttctcatcat catcttcctg ccccggggac
    50161 tcgtatccct cccggaggaa attggaaaaa agtgggggag aaaagggaag taaggcagca
    50221 ggggaaaaga ggcaggagat ccctttttat aacccgaggt atgcctcgcg gatctgctcg
    50281 tcgtgcagga gctctgacga gcgtcctgaa cgggttatcc ttcctgcctc gatcacgtag
    50341 gcccggtggg aaatctcaag agcccttctc acgttctgtt cgacgagaag gatggtgatg
    50401 ccttcactgt tgagccgttc cactgcttcg aggactgtgt ggacaagctt gggggagagg
    50461 ccaagggacg gttcatcaag aacaatcatc cgcgggttgg ccatcaggca ccgcgcaatt
    50521 gcaagcatct gctgttctcc ccccgatagc gtgccggcgt cctggtcctg gcgttcggca
    50581 aggtggggga agagctcgaa aacccggtca gggtcgcctt tcctgccggt cgcaaatgcc
    50641 ccgagttcca ggttttcccg gacggtcatg cggggaaaga gctccctctt ttcggggacg
    50701 agggagagac cgcgcctcac gatctcgaac ggtgccatgc cgctgatatt ctcgccctcg
    50761 aattctatcc gccctccgat tgcggggacg aggccaaaaa gcgctgatac gagcgtcgtc
    50821 tttcctgcac cgttcgaccc gatcagggtg acgacttcgc ccctgtcgac gtgcagggac
    50881 acgtcccaca acacctggag gtaggagtaa gagacgttga ggtcttctat gtgaagcatg
    50941 gggggcacgg tccttccctt ttagaaatgg tagcgctccc cgagatatga atctatgact
    51001 ttttcgtttg taacgatctc agcgggctct ccctctgcga tcttctctcc atggtcaagg
    51061 accactatcc ggtcggaaac ccccatgatg atccgcatga cgtgctcgat catcaggatg
    51121 gtcattccct cgtcacggag tttcctaatc agggaaacag cttctttccc ttcgctcggg
    51181 gtgaggccgg ttgtcagctc gtcgaggagg aggaccttcg gatgggacgc aagggcccgt
    51241 gccagctggg tgcggcggag ctcgaacgtg ttgaggttcg tgatcgggct gtcaatcttg
    51301 tcttcgggaa aaccgaccat acgcaggcac tcctctgcct cccgggatgc ttccctgaca
    51361 gtggggcggc ggccattccc gtacagggca ccgatcatca cgccctggcg ggcagtgagt
    51421 gcagggaatg atcggggatg ctggaacgtc ttggatatcc ccttcttgca gacagcgtcg
    51481 agggagaggc gggtgatatc ctcaccgcag aagacaattc ccccggcgtc cggccggtag
    51541 atacccgaga tcaggttcag gagtgttgtc ttgccggcac cgttggggcc taccagtccc
    51601 aggatctcac cctcgttgag agtgaggctg acctggttga ctgcaacgag gcccccgaac
    51661 gacttggtca cacctctgac tgtcagcatt ccatgcaccc tgctaacaaa tagcatgata
    51721 tatgttaaca tacagcatat taaacatatc cttcggggga gacagaaatg gtcagaccag
    51781 tgtatattgg tgcagttctc ctgctcgtcc tcgcacttat ggcaggatgc accgagcaga
    51841 aggcacagac acaggagaca ctcaagatcg gtgtcgtggc ctcgatgacc ggggccgcga
    51901 gcacgacggg aaaggacatc tggcagtctg cagtcattgc cgcagaagag atcaacgcac
    51961 ggggcggtgt ttacataaaa gacatcaatg ccagggtccc gatcacactc atccagggtg
    52021 atgatgaatc gtcaagggag ggcggccaga aggcagtatc ccgcctgatt acccaggatg
    52081 gcgtggatat cctcgtcggt ggcttctcga gcgccgtcgt atcggcccac caggcaaccg
    52141 tctccgagta caaggtcccc tacatcatca ccggtgcctc gacaccgaca atcacacagc
    52201 ggaccgatat cgatacgggc acgatgttcc actactgccc gacgactgac gattacgggg
    52261 aacagacaac gctctttgcg tacgaagtca tcaggaaagc catcaatgaa aagttcggtt
    52321 accccgattc acggcccctg cgcatggcac tcatcatcca ggacagcccg tacgggaagg
    52381 gtgtccagaa ggccgtgaag gagacaatcg aaaagaagaa cctctccatc gtgatcgtgg
    52441 cagaggagac gtacaagatg ggagagactg acttccggac ccagctcacg tcaatcaagg
    52501 cagcgcaacc cgatgtggtc tatcccgccg cattcctcaa cgagcagatc ccgatggtga
    52561 cccaggcacg cagggatgtg gggctcgata ccatcttcct tgcggtcgaa tgcaacgatg
    52621 accctgacta ttatgccggc cttggaaagt acggggaata ctccgtcatc gagacccggt
    52681 tcagtcccta tgcagtcccg aaagggcctg ttgccgatga catggttgcg ttccgggaaa
    52741 acttccacaa gcgctggggt tcgtatcccg gaatgatggg cgcctcgacg tacgagggta
    52801 tctatatcgc cgcacatgcc gtcgagaaag cagggacccg ggataaggca gccgtgacac
    52861 gggcgcttgc caccctcgag atgccccaga tggtcgaagc catgaaagac ggcgtaatta
    52921 agttttcacg agattacagg gaggcaaaat tcgatctctt catggagcag ctggtatgga
    52981 acgagactgc aggcgaatta aggccgcgga tcgtctggcc ggatcacatg aaggaggctg
    53041 acttcgtgct tcccgactgg tacgtaccgg ggccggcagc tgccccctga ttcccgcggg
    53101 cattccaaag ttccgggcct catggagaag gcggaggatt tccgccttcc gttttcctgt
    53161 atttattccg gggaacgagg atctcgaagc gtgcaccttt gccgtattcc ccggtctccc
    53221 ggatttccat gccgtacacg gagaggatgc cacgggcgag aaacagaccg atgccgaggt
    53281 tcctgccgac tccctgctcg aagatcagct ctttctggtc agggggaatc ccgataccgt
    53341 tatcctcgta aacgaggacc cccttgtccc ctgattcgta aaatgaaagg gtaatcctgt
    53401 caactctctc accatgcgat accgagttat cgatcagcgt ggaaaagatc tttgccagaa
    53461 ggcgatcgga atagatgaaa agattatcga agagtacctc ggccttcaca ccgaaaagtc
    53521 ccattcccat cgccacctcc aggaatagtt ttctcacgtc gatccatccc acagaggacg
    53581 gtgaagcctc aagttcgtac tccctcatga aggccagctg gtgctcaatt gtctttgctg
    53641 cagatttgat ctttttaagg tattcaatgt cagcagagtc ctgtgggata ctctcggaga
    53701 ggagatcggc aaatccccgc actattgtga cctggttgag gacgtcgtgt cgcgtgatgc
    53761 gggaaaggag tgtcagtttt gcattcgcaa ggcgggcatc gtcctttgcg gcagtctctg
    53821 ccgcaacgtg ttcatcaagt gcatccagca tcctgtcgat gctcgtggag agtgaggaga
    53881 tttcgtcgtc gcctgaaagt gcagtcctcc ccttgaaatc cttctgttcc gtaatctctc
    53941 tcacagtttt ttcaagcagg gatacccgcg agaggacttt cctgtccagg aaacggattg
    54001 ctgttattcc gatggcccct cctgcgagta ccacgatgac gaagaaaagg atgatgctgt
    54061 ttttggctat ctgaaatacc gttctttcga gggtgatgct ggtaataaaa gcaggagagc
    54121 cggaaatatc gttgatggtc gactcggcga cgaggtattc accggtagcc ggaagtcgta
    54181 gggtaatcgg gattgcctcg tggaaacccg gggacatggc aaagcccggt tcatcagcgg
    54241 gcccggcttc cctgaaagtg aggttggcca tggccaggga tgcataatgc gtggtctcgt
    54301 ccccatcgag atagcgcccg atgaggaggt agcctgctgc cggtccggtc cggtcgttgg
    54361 ggaggatcgg cccgatactt gcgaggagcg gtccgcggga agtgctgatg accccgctga
    54421 ggggtggaac atcatctccg gagttgtttg agtcaggttc cggaatggcg gggatatgcg
    54481 ataaatcatc agggatggaa agtgcgacct gccttgaata gtcaaacccc tttccgtaaa
    54541 cgagtgttcc attggtgtcg tagaagagca tcaggtcgag ccggagggcc agaaatgttt
    54601 cattgaccag gttttccgcc ggataaccct cattctcccc ttttgcaaaa taatacgtat
    54661 catcccattt tccccagtct tcgcaggtac ctccgagtgt tccaagatcg tattcgataa
    54721 tccggataac tttcagaacc gcattctctg cttccctttt ttcaatatct tttactgcag
    54781 gatagagtgc cagctgcgtt gccactgcaa caatcagcag ggaaatgacg attactatga
    54841 tgaaagtgag agtgacactt gaacggattt tcatcctgca attacctcgg agatcgaaaa
    54901 acccggctat tttcggattg tttaaatgtc catcttttcc ctgattataa ttgtgttttg
    54961 ggaaccagtt cccatcttca ccattcaggc cttaccaggc aagaaacgat ctgataagca
    55021 ggacaccgag tcccagcagg acaagtccca tgatgatgcg gacggccctc cggtgttcct
    55081 gcctccagcg gtcaactctc tccaggggga ggccaaacac gacggcacag aggatcagaa
    55141 cgaggggcag tacgaagaag acgttgtaga cgaggagcag ggggattcct tctgccatcg
    55201 tcattttatc ggatatcagg gaaaggattg ccaggtagat gccccccgtg cagggcagtt
    55261 cgaacatgcc caccagtaca ccgaggataa tggatgccgg gactgatgcc ttctggatat
    55321 aatccccgat tatgcctttt ttcgaaccgg ggatggcaag ggtgggcttt tcccggtcaa
    55381 aaacaccttc aaagaggctt attgctccca ggatgaatgc gattcctgct gcaataattc
    55441 caatcgcccg cgatatctcc gcgagctgga tgagatagaa tatgccgagg ccggagagga
    55501 aataaaagac aaaaacggtc ccgatgaagc aggctccaac ggtaaccatc tttttcctcg
    55561 accctgcaac agaaagggtg aagaggagga tgatcagcac agagaatgcg cagggattta
    55621 tcccgtctgc aagacctgcc acgatgacca gcgggatggt catttcctgt gctgatatat
    55681 tttcaagcga agggaatccg ggggtggtcc cgggggcagg accgtggctc tgttctttta
    55741 ccacttcccc gagtgaccct gttatctcgt cgtaaccggt aagtaccctg tcccccacga
    55801 agatggaggg aacagggatc ggtcctgtat tgtacgcatc tttatagacc gaaaagagct
    55861 tccagtaatc gaaattctcc ttaatgttca gcaggtgtgt ttcgagttcc gggtgttcac
    55921 tgacatactg ctggacgaag gggagagtcc tcatgcagtc gccgcagttc gtgttgtaga
    55981 acatcacgat aacaggaccc ttgtccgtga accggtggtc gggactcacc gggagtgcag
    56041 gctgctcttc tccggcggag ggagacggaa acccctggtc tgtttcttcc cgggctgtta
    56101 cgggaaagat gcatgcaagg atcaggagag ttgcaaaaag gagaatgaaa aaccgggttt
    56161 ctcttctttt tttattgcct gccattcaat cacttttctc acgggcccac cggggctgcc
    56221 ggacttatac aaattatatt gaaatagttg gtctgatgag atatagcatt ttcccacctg
    56281 ttggacccgt ccggcaagct gtcacggacc tcctgttaag aacgaacccc ctttttagag
    56341 aaaacgagga gaaaaaaccc ttcctcattc ctccgtaaca gagatgatcc ggacgggaca
    56401 gagagcggct gcctccccga cgcagccttt caggctgtcg ggaacctctc cttcggatat
    56461 actcccgcct gcgcggtact tttcccgtat ctggctgaag ctgtcgtcac cattctcttc
    56521 gaacacctcc gggcaggtct cccagcaggt actgcacgc
//
LOCUS       DAOOJU010000011        56254 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_656_length_56254_cov_14.772647, whole genome shotgun sequence.
ACCESSION   DAOOJU010000011 DAOOJU010000000
VERSION     DAOOJU010000011.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 56254)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 56254)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56254
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_656_length_56254_cov_14.772647"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..848)
                     /gene="argF"
                     /locus_tag="PK679_04320"
     CDS             complement(<1..848)
                     /gene="argF"
                     /locus_tag="PK679_04320"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HPC55215.1"
                     /translation="MKRDLISILDITAGELDHLLDMAARMKEMRRAGKPHRCLPGKTL
                     AMIFEKSSTRTRISFEVGMAELGGTALFLSVHDLQIGRGEEIRDTARVASRYVSGVMI
                     RAYRHSTIEEFARYATIPVINGLSDLEHPCQILADIMTIREHFTKTEGIRVGWVGDGD
                     NVCNSLILSSALTGMEVTVATPPRFQPPEEILGRARAGGGRVRVLSDPREAVRDAHVV
                     VTDTWVSMGTEEERDARLRAFSGYTINAELMDLAAPDAIFMHCLPAHRGQEVTDDVIE
                     GPRSVV"
     gene            complement(845..2137)
                     /gene="purD"
                     /locus_tag="PK679_04325"
     CDS             complement(845..2137)
                     /gene="purD"
                     /locus_tag="PK679_04325"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HPC55216.1"
                     /translation="MTMKILVVGGGGREHAIAMALSRNSDVDLYAVMAQQNPGIAKLC
                     RKFSIGKETDVAAVTRFAQQNSLDYAIIGPEAPLEAGVVDSLEKAGIPCVGPTRAAAR
                     LETDKAFCRKMMESHGIAGCPRYRAFRTAEDAISFLKEYPGDLAIKPTGLTGGKGVRI
                     VGEHVDRKGAEEYIRGLQGGVVLEERLLGEEFTLQAFSDGKNIIPMPLVQDHKRAYEG
                     DQGPNTGGMGSYSLPDHTLPFVTGSDRERALDIMRSAVAAMENAGTPYRGILYGQFMN
                     TRDGPMVIEFNARFGDPEAMNVLSLLETDLFSIMERIVDGTLGNMPVRFSRKATVCKY
                     IVPEGYPEAPVTGEPLTIGPYEPAILYYANVEERDGTLYTRSSRTLAFVGLGDTLPLA
                     ERIAETAASNVRGRVRHRRDIGTQELLERRISHMRELR"
     gene            complement(2156..2689)
                     /gene="pyrE"
                     /locus_tag="PK679_04330"
     CDS             complement(2156..2689)
                     /gene="pyrE"
                     /locus_tag="PK679_04330"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HPC55217.1"
                     /translation="MVNEIVQLLLRYGALEFGEFVLASGEKSSYYLDIKKVVTRPEAL
                     QLIAALIARRFEFDTVAGVAVGGVPLAVAVSLESKKPFAIVRSQEKGHGKSGRVIGDV
                     SGRRVLLVEDVTTSGGSAIQGIRALREAGGIIDTAVVVVDREAGAVESLGREGVRLEA
                     LAKASEILNAGRENSKR"
     gene            complement(2683..3183)
                     /locus_tag="PK679_04335"
     CDS             complement(2683..3183)
                     /locus_tag="PK679_04335"
                     /EC_number="2.7.7.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
                     synthase"
                     /protein_id="HPC55218.1"
                     /translation="MLPAYVPNSVAACFGGGRPIDGGRTLSDGTRIFGDGKTYRGFFA
                     GVAGGIIVGLVQMALQGSLDLSFLPAQTPLSVLLLAVGALLGDLLKSFFKRRLKIPSG
                     GKWPVADQYDLVAGAFLLLALFDPAWLLGAVTLPVLFWILVLTPLLHKMANVIGFITG
                     VKDVPW"
     gene            3318..4790
                     /locus_tag="PK679_04340"
     CDS             3318..4790
                     /locus_tag="PK679_04340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC55219.1"
                     /translation="MPAILKKTRSLCPKCNAVLDATILEDGGKVWLERTCPEHGHFRD
                     LYWSDAELWKKFERFESIGKGIENPHRDAPPDGCPSYCGICTNHKSATLLANIDLTNR
                     CNLNCDFCFANARACGYIYEPTFDQVMAMLRLLREEKPVPTPAVQFSGGEPTMRDDLP
                     RIISAAKDMGFPQVQIATNGLKIARDISYLRELKDAGLSTLYLHFDGVTKETNFKIET
                     DKKVVGNCEELGIGIVLVPTIIKGRNDHEVGAIIRFAADHIRVVRGVNFQPIAFTGAA
                     SEEDVARERITIPELLQDIESQTSGIIKKDDFYPVPCVVPISDFVEAFTGKPQIRFTA
                     HQHCGAATYVFVNDDGLTPVNRMVDVENFLSALNETAEKLKKGGFLMKYRALFETISQ
                     LNHSVKKDEYKTGRDLWKLLGKTLIFHNFDALREFHWNALFVGTMHFMDRYNYDLSRV
                     QRCCIHYATPDGILIPFCTYNSGPVYREVVWKKWSKPLDT"
     gene            complement(4914..5849)
                     /locus_tag="PK679_04345"
     CDS             complement(4914..5849)
                     /locus_tag="PK679_04345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314943.1"
                     /note="catalyzes the interconversion of alanine and
                     pyruvate; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HPC55220.1"
                     /translation="MRYYPDPARDIDLRRVNRAIEEAFAEHARGHVQMPPKLYVTLEK
                     GDFRTMPAYIPSLGIAGVKIVNVHPGNPSLGLPTVMALTVILDVETGRPESILNATGL
                     TDIRTGAAGAVAAKYLSPKRKVRLGLVGSGRQARAQVMAIGQELSITEVLVWSRNRAN
                     AEKFCEDTLLPECRSEDLKTVCDCDILVTTTPSREPLVMDRWISGGTHINAIGADAPG
                     KQELDPAILRRATVFVDDPAQAIHSGEINVPIAKGLFDPGRIAGTLGEVVIGRKGRKS
                     PDEITVFDSTGLAIQDLAIAAIAMGSAEAIDLPFL"
     gene            5984..6778
                     /locus_tag="PK679_04350"
     CDS             5984..6778
                     /locus_tag="PK679_04350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HPC55221.1"
                     /translation="MIHIIPKPTDTPGDNSTSMVAREITRRGGDYALIDPADIDPFTT
                     GLSDSLIWVCGLAQDEVQFEVINALSVDNRVINSPLAIFTCASKVLTSTLLVRRGIPT
                     PETCFTQSRETAAAFLSRHKKVVSKPVYGYDGHGIILVQSPRDLGPPPYYLQEFVPND
                     RDFRVFVIDGEAVGAIERVSDTLAHNIHQGGTGRPVLIDSLMADRAVAAARAVGVDYG
                     GVDLLRRGDDYCVLEVNGTPNWHCMGVNIPGLLAEYLLEQERMGRK"
     gene            complement(6811..7095)
                     /locus_tag="PK679_04355"
     CDS             complement(6811..7095)
                     /locus_tag="PK679_04355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0058 family protein"
                     /protein_id="HPC55222.1"
                     /translation="MHKEELITLHQMLSEIKDYFESINSDLKFSNYYSLKINPSQLHK
                     SKMEHKYAIFVLGNELADAMKEVEFSASGRISARMRELAAKTLKEMEYVQ"
     gene            complement(7159..8403)
                     /gene="dnaG"
                     /locus_tag="PK679_04360"
     CDS             complement(7159..8403)
                     /gene="dnaG"
                     /locus_tag="PK679_04360"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase DnaG"
                     /protein_id="HPC55223.1"
                     /translation="MYSSDTTKYLIHIHLDAEGVVEKPDVVGAIFGQTEGLLGEDLDL
                     RDLQRTGRLGRIDVQVTSKKGETKGEIYIASSLDRAETAILAASFETIDRVGPCAAKV
                     RVESIEDIRVSKRKQVVARAKELLLDAFEDGSIDSTLLIDEVRESMRMEKIGTVGEDK
                     LPAGPNVLESDAIIIVEGRADVLNLLRFGIKNAVAVEGSRIPRTIIELCEKKTATAFF
                     DGDRGGDLILRELLQVAEIDFVAYAPRGKSVEDLSRKEIVKALRNKIPADYVREEPVG
                     EEDDEKTPQLNPAGVPDEGAPAGEGAVQRKKREPKAHQASAAEKTGPRTLSEHLSEVR
                     GQRMARFLSSEYTVLREVKLDDVERTLEELNGNARGLVIDGEVTQKMIDRMVGKGFEY
                     VAARGYKGIIKRPLSMRLLKIT"
     gene            complement(8544..8867)
                     /locus_tag="PK679_04365"
     CDS             complement(8544..8867)
                     /locus_tag="PK679_04365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF167 domain-containing protein"
                     /protein_id="HPC55224.1"
                     /translation="MDDYRGALTPTRKGTVIALDVTAGAKETAFPHGYNAWRKSIVFL
                     VREPPEGGRANEEIVKVISQLFSLPSSRVRILSGASSHRKRVLVEGLDQEKVLAILSG
                     HGSSG"
     gene            complement(9029..10336)
                     /gene="pyrC"
                     /locus_tag="PK679_04370"
     CDS             complement(9029..10336)
                     /gene="pyrC"
                     /locus_tag="PK679_04370"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HPC55225.1"
                     /translation="MTPAPHACDLVLRDVLLPGGRVADISIRDGRVCHVGAALASSQV
                     VPCRGKIVLPGAIDMHVHMRGRSQKEKEDWTSGSRSALAGGVTVVVDQPNTVPPLNTP
                     ESFSERVREAREGSLCHFAINAGVVPGTDPSPLWSAGAMAFGEVFTAASSYGSGLTPA
                     ELAMVLDSVGAIGGLCTIHAEEVGRGDDRDLRSHHAIRSPDGEARVVEDVRKMNRKGC
                     RLHFCHLSSAVSVLRAGDATVEVTPHHLFLALDDFAARDPRGKVNPPLRPEVVRRELW
                     SVWERIDVLASDHAPHTVQDKEQPFPDAPAGIPGVETMVPLALAACRRKKISLSTLVE
                     KTNLNPARILGIPPAGFSVGDRADFAVYPRHESRIIADELHSRAGWTPFEGMPAIFPE
                     TVVMAGDIVYRNGAFGTGRPRWFMGRGYIHGTQRENGADSARP"
     gene            10537..11901
                     /locus_tag="PK679_04375"
     CDS             10537..11901
                     /locus_tag="PK679_04375"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC55226.1"
                     /translation="MKPVMTIILVSILLFLVTLPAGAEETLPGTVTPAETQAVTEAVT
                     LPGSIGGDVGYFSIDSVPSGADVIFDGKYLGETPIVAEVYTTASPSHTISVSRQGYKT
                     WIQTYSRNPAAGQTIEVTANLEPVVQTGSIQVTSSPAGAIARLDGGETLVTPGTFRYV
                     PPGYHTVELALYGYFPYSTSVNVAAGGTSSVSASLSPMQTTGSLRVTSSPSGAEIYVD
                     EIYRGYTPLTIGSLSTGRHEVRLHLSGYQDYTRTVEIESGSQSSFSVTLTPVYQPTTG
                     DIVVTSVPDGAAIYLDGNYRGTTNERNPFDITGVAPGTHTVTLLKNRYKDYSADVTVL
                     AGKTVTVSAVLTPGSVTPSTGDVSVESSPSGAEVYLDNAYEGFAPLTIHNVPAGSHVV
                     MLRMSGYQDFQYTVQVSGGQTASVIGGLTPVPTTVPTKSPLSPAVAVLGVLAGLALLY
                     VGRE"
     gene            complement(11943..12027)
                     /locus_tag="PK679_04380"
     tRNA            complement(11943..12027)
                     /locus_tag="PK679_04380"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11989..11991),aa:Leu,seq:cag)
     gene            complement(12089..13786)
                     /locus_tag="PK679_04385"
     CDS             complement(12089..13786)
                     /locus_tag="PK679_04385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HPC55227.1"
                     /translation="MAAAEHNMHNYQEVYDHFSLEVPEYYNFAFDVIDRIAEKDRNRL
                     AMIWVNQEGKEKTFTFRQLMNLSNSAANMLLKYGIKKGDRVIIMLPRVPEWWIFALAC
                     IKLGAVFCPCPTMLTPKDLKYRINAAKIRMVITDRENAGKIEEICSSCPTLQSRLVTD
                     AELPGWISYTVEQEYPAPVSRKLVSMTGMERTKATDPLVIYFTSGTTGEPKMVLHNHA
                     LPLGHVTTGRFWLDLTENDLHFTLADTGWAKSSWGKFFGPWIQGACILVYDIRGKFKA
                     TELLPILEKYEVTVFCAPPTVYRMLILADLKKYDLKELRHCVSAGEPLNPEVIRVWKE
                     GTGLQIYEGYGQTELVLVIGTFPCMEPKPGSMGKPAPGWHIELHDEEGKPVPPGEVGR
                     IAIRVKPRPVGLFEGYLYDKEATSAVFVGDYYYTGDKAYRDDDGYFWFVGRDDDVIKS
                     SGYRIGPFEVESALLEHPAVKEAAVIGSPDVIRGMIVKAFIVLKDGYQPTDQLAKDIQ
                     KFVKKITAPYKYPRAIEFVDDLPKTISGKIRRNVLREREMRAKSGQENLSGGKEGTG"
     gene            complement(13948..15615)
                     /locus_tag="PK679_04390"
     CDS             complement(13948..15615)
                     /locus_tag="PK679_04390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HPC55228.1"
                     /translation="MEGIPAAKGDYEDLCRNFSITVPRYYNFGYDVIDSWAQKDRNKL
                     AMIWVNQEGCEKKYSFRDLKNLSNQAANILIKYGIQKGDRVLLIMPRIPEWWVFMIAL
                     IKLGAVVCPCPTMLTPKDIRYRLNAGKFKMVITIKEHVEKVNEVADDCPSLTCRFLVD
                     GELPGWISYPVELHYPAPVSHHSVSMPVGKKTLSSDPMLIYFTSGTTGEPKMVLHDHS
                     YPLGHLVTAGLWQDLTPHDVHFTYSDTGWAKCAWGKIFGQWIIGACLFIYDARGKFKA
                     TELLPLMEKYEITTFCVPPTIYRMLILADLEKFDLRELRRCVSAGEPLNPEVVRVWQE
                     GTGLPIAEGYGQTETVCCIGTFRDMKVKPGSMGKPAPGWQIELHDDEGRPVAQGEVGR
                     IAIRLDPRPVGLFVGYLDNDQANAESFVNGFYYTGDKAFMDEEGYFWFVGRDDDIIKS
                     SGYRIGPFEVESALLEHPAVAESAVVGSPDLIRGTIVKAFIVLKPGFEPSERLVKDIQ
                     AFVRKNTAPYKYPRAIEFVPDLPKTLSGKIKRNELRRMEMEKFNNSH"
     gene            15741..16295
                     /locus_tag="PK679_04395"
     CDS             15741..16295
                     /locus_tag="PK679_04395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TATA-box-binding protein"
                     /protein_id="HPC55229.1"
                     /translation="MPGTENRSLKIENIVASGSIADSIDLAEISSRIENCMLNRKRFP
                     GAVFRLEKPKAVCLVFSSGKIVLTGLREKEALDEAISRIVSAMKDAGVRVHSRPLVTI
                     TNIVCSYDAGKIINLNKLVVTLNMENIEYEPEQFPGLVYRLKDPRIVALLFSSGKIIL
                     TGGKNLDEIRRGADLLEQTIGMVS"
     gene            complement(16298..18982)
                     /locus_tag="PK679_04400"
     CDS             complement(16298..18982)
                     /locus_tag="PK679_04400"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HPC55230.1"
                     /translation="MIPNLDPRVSQLVRDRGFTRLSPIQQAAIPLVREGKNLILIAPT
                     GTGKTESAMIPVFDAMLTGKGQGITTLYITPLRALNRDMLSRLSWWCSNLGFSVGVRH
                     GDTTQTERRKQALSPPDLLITTPETLQALLMGRVMRKHLAGVRYVVVDEIHELAGSKR
                     GAQLAVALERVREYAGEFQRIGLSATVGNPRDIGQFLCGRREFSVVSVPVAESLDIRV
                     EFAGDSFDSQCDWISGAIDRHSSTLIFVNTRVTAEALGHRLYPRGDVEVHHGSLSREV
                     RIEAEERFRKGDVRCLIATSSMELGIDIGRIEHVIQFGSPREVMRLVQRVGRAGHQLD
                     VVSRGTVLSTGFDDLLESLVIARRAHAGQIEEVTIPINAADVLANQIAALAVEYREIP
                     LPKVKEIVGRSYPFPDAGDLVDEVCAQMAEHHLIRIDGDRVRSSARSRRYLSGNLSMI
                     PDERKVTVFDMVSRKTVGTLDESFVAGFIHTGVVFVTKGQLWRVLDIDEGRITVEPAR
                     KVKGEIPSWEGEQIPVPFSIAREVAMLRRTRDFSSYAAGKDPASFAARFLEEMDRNRT
                     PVPDDTLISLENVPDGVVCNVCAGHMANEALARVLSILLSARFGTTVGIEIDAYRIFL
                     RLPPAVKAADVKETLLSLDPAHLEGILQLAMKRTALFKWKMVQVAKKFGAIDPDADYE
                     KISVSRLIETFEGTVVQKEAYRELFSVYMDVPAAARIVSLVREGSIRVAISHQSLIGA
                     AGLFSSRDMIPPPAADQAVIATLRRRIDQQEIILFCMNCRKWKSRTVVSRVPDPPRCP
                     RCQARLIAVLKPWEEPLIAQVSKKQKTEEDRAIEMKLLRNANLVLSSGRKAVTALAAR
                     GVGPENAARILSTLTEGNAFYTEIIRAERNYIRTRKFW"
     gene            complement(18966..19733)
                     /locus_tag="PK679_04405"
     CDS             complement(18966..19733)
                     /locus_tag="PK679_04405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HPC55231.1"
                     /translation="MKMEFLPDGPALVVENRERVLVAGDLHLGIEPSLSRQGVHIRSR
                     SRERIDRLIACIESAGPDTLALLGDIKHGVPFTTRQEMREIRDFFDEIRSIIPFFVLP
                     GNHDPGIEEFLRPDELFPRDGALVDGVGYLHGHTYPNPALRGHLILAGHHHVMVSVRD
                     EVGCALRAAGYLLARVNETCLQFPPGGDESGTVTRALFVPAFCELAGYDIQHMIRDPI
                     SPLSRCIDIPTSELFLSDGTFLGPLSLLEEDANDSEP"
     gene            complement(19730..20497)
                     /locus_tag="PK679_04410"
     CDS             complement(19730..20497)
                     /locus_tag="PK679_04410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55232.1"
                     /translation="MMFQRVFAAEFNAATVQFSREGMAEPAVLTPGGALLTLVFASGA
                     LLERQGCGNETVRARMADPTGAFSLQADPQSPDARATLCSLETPCFATVVGKPFLAGT
                     GRPAPCILRVLDIRAADRYTRDTWVLRTAEATLDRLERIGAALRSGSEDPLVRALVTS
                     YSLNPARLCSLAGTVRDAVQSVQSQSPPAKSELSPESVVLAIMKEHGGKEGITLEEIV
                     RRAANHGLTHQDVLSAVEVLCREDECYQPSRGTFKLL"
     gene            20816..>23271
                     /locus_tag="PK679_04415"
     CDS             20816..>23271
                     /locus_tag="PK679_04415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SBBP repeat-containing protein"
                     /protein_id="HPC55233.1"
                     /translation="MRSKGLACFVILSLVLVSVISASQVPFPVDPSGESTLMPVRQVD
                     PAQGQDQGRVQGGTQAIPLQFVKNAGQSDDGVEYIVLTDGGSLFFAPGGVSIKLVTPD
                     GQTFRTTSLGYSFYGADPDPEMTGLFPRESTVNFLLGKDPSSWYTDVPTYGAILYRDL
                     YPGIDLEYCGTSDGIKSVFTVAPGASPDSIIIEYRGVSGLSLTDEGALRIQTPAGDLL
                     EYPPVAYQVIDGQVVPRDVSFALHGNNRVGFSTGSYDPEFPLIIDPVMKYGVYLRGVG
                     LAYGRSVAVSPDGSAFVTGETFPAPYSLQGESIGPLGGGMDVIVVKVNPEGTVPLYVT
                     YIGGSGNETGYGIKVDASGYAYVTGVTDSQDFPVKDALQGYLAGDTDAFALKLSPDGS
                     NPVFSTYLGGTRPDSGNDLALDRFGNILIAGDTSSFSMPDIDHSTHTVYGGNQDAFVL
                     KLTGDGKEIVYSEFIGGNQKDAGNGVAVDRDGNAYVTGETSSKDFPVKNAYQSSLSGG
                     TWSDAFITKVSPGGETFVYSTYLGGPQIDVGHAIAVDSYGHAHVTGSTLMSVFPVKNA
                     FQPVSGGAMDAFYSYLSADGRELLYSTYLGGSCNDWGTGITTDVYNTIFITGSTASLD
                     FPLVDPFQPRFGNGDPKATDAFVAKFCPFETRPDYLTYLGGTGSDNGASVATDGVDGA
                     YITGFTDSPNFPSSDPYPPAFEPKGQGGFLFVLRDDACTPPCELPVAGFAANPASGHV
                     PLTVNFTDTSTGNPVIWSWDFGDGETSPDQNPVHTYTAEGTYTVTLTVTNECGPNSTT
                     KQEYIHVLPPCVPPVANFSA"
     assembly_gap    23272..23371
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <23372..25702
                     /locus_tag="PK679_04420"
     CDS             <23372..25702
                     /locus_tag="PK679_04420"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55234.1"
                     /translation="VLPPCVPPVANFSANPTEGYAPLDVTFTDESTGVPTSWQWSFGD
                     GATSTDRNPFHTYNLSGTYTVTLTVTNDCGSNSTTRQEYIHVLPPCEMPVADFLAHPT
                     WGFVPLCVSFFDTSTGNPSSWYWEFGDGATSSEKNPVHLYSQTGTYNVTLTVTNDCGS
                     NSTTKQEYITVVPPCDLPVANFYGNPRTGTNPLLVEFCDLSTGGIISWHWDFGDGATS
                     EEQNPIHIYEQAGNYTVTLTVTNDCGPDTETKTSYITVSQSPSGPPVAYFAANTTLGI
                     VPLPVAFYDLSYGNPATWQWDFGDGGTSSERNPVHVYRSAGTFSVSLTVANPNGTSTF
                     TRPEYITVLSPIGGDTGYFRVHCNVDGATVHFNQDYKGQIQDGILLVMVYLTGSPYTS
                     YTVAKEGYYPVTQPITAYPAKDQTVDLYAVLEPIPTINYTVTATAGPNGTINPSGTMT
                     APAGSSIDFTIVPDTGYNPRSLSLDGVDLGALRSYRLSDIQANHTLHAEFEKAIFGIT
                     ALPSENGTIVPSGLTLVPYMESRDFQIVPDSGFYTAGLYIDGVGVAPVPVYTFSNVVS
                     NHTISAVFLPEGSLTFYIDAVAGEGGTISPSGLVSVAGGSNITFTMTPLTGYYTKNVM
                     VDGDSKGAHETWTFTNVVSNHTISVTFEKSGGGGGGGGGGGGGGGGGPFVTPTPTAVP
                     TSQATETEGYESGGTVTIANATPTLTTVPTETPAEEETTTVATTTIPPATPYWTGFSL
                     YWLLLLLIVIAVLAAVGYYYWKKEQAKVALFEEEGR"
     gene            25911..26876
                     /locus_tag="PK679_04425"
     CDS             25911..26876
                     /locus_tag="PK679_04425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication factor C small subunit"
                     /protein_id="HPC55235.1"
                     /translation="MEENNLIWIEKYRPVRLADIVGQDQIVERLSSYVRTGNLPHLLF
                     TGSAGVGKTTAAVALAREFFKDSWHMNFRELNASDERGIDVVRNQIKQFARTSPLGGA
                     GFKILFLDEADALTPDAQAALRRTMESYASTCRFILSCNYSSRIIDPIQSRCAIYRFR
                     SLSPEAITKEILRIAENEKLTITGEAIDAIIEIAQGDMRKAINALQGAAILSPEITGD
                     MVYAITATARPDEIEDLLSTSLSGDFEGATAILHRLLNDRGIAPNELINQCYRALTRR
                     DMEEDMRVALIDQLGTTDFRLSEGASSDIQMEAMIARFVLLARKK"
     gene            26873..29014
                     /locus_tag="PK679_04430"
     CDS             26873..29014
                     /locus_tag="PK679_04430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minichromosome maintenance protein MCM"
                     /protein_id="HPC55236.1"
                     /translation="MKRKEPAPDTEADAEVIDRDADWSRFLKSRYRKQLSELAREYPY
                     RRSIEIDYRELESYGKTGLRMADELLENPGKVIEDVRNAIRNHQLIKGKDGKPTGDVN
                     VRFINLPRKIGIRHIRSDHINKFISVEGILRKTTEVRPRIVQAVFRCPAGHITIKEQG
                     YGRFREPDGCATEGCTFKKLELMPRRSRFIDSQKIRIQESPEGLRGGEQPQTLDVDVT
                     DDLTGKVAPGDRVVINGILRSVQRVTHGEKNTVFDIYLECNSIEIAEKEFEEVQIDEK
                     DEETILALSRDPQIYRKIVHSIAPTIYGNEDVKEAIALQLFGGIAKEMPDGSHLRGDI
                     HVLLIGDPGIAKSQLLRYVVKLSPRAIYTSGQSSTSAGLTATAVKDEFGDGRWTLEAG
                     ALVLADMGIAAVDEMDKMQKEDRSALHEAMEQQSISVAKAGITATLKSRCALLGAANP
                     KLGRFDDYLPIHDQINMPGSLLSRFDLIFKMSDKPDHTRDSAIASHILKAHSIGETIA
                     QHRHSPIPGVDDKYIEEQLKPVTPEIDPGLFRKYVAYARRTCFPRLTEEAREALSAYY
                     MQLRDLAAGSDKPVPITARQLEALVRLAEASARIRLSQEIGREDAERVIKIVDACLRE
                     VAYDPKTGTFEIDRVSSGITKGRRDLIRTIKQTIRQIQKDTGNDRVAVAELMDILVPQ
                     GFSREEIKAQIELFLREGEAMEPKSGFIKLI"
     gene            29058..29381
                     /locus_tag="PK679_04435"
     CDS             29058..29381
                     /locus_tag="PK679_04435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase family protein"
                     /protein_id="HPC55237.1"
                     /translation="MISAREKAIFEAGIKLGALYHQWVGSPVSPQTAATLERAIEASV
                     SLQPFVERVTVQLDRSLMAPNTFGYSELSGLMFDVEIVTRVDGVACRAKLRRDGTYPL
                     MEIVE"
     gene            29382..30209
                     /locus_tag="PK679_04440"
     CDS             29382..30209
                     /locus_tag="PK679_04440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HPC55238.1"
                     /translation="MSRPSSPVTDDHIHIDPRNGRGLAAARDFFRSGGTHIFLVSKPS
                     SSFGILPLCGEDFRPVFEETLSVAEMVSGTGVVVFPVLGVHPAEITRLLEHVPLERAA
                     GIMKEGIDLAARFVEEGRAVAIKSGRPHYEVPADVWTASCEVLSYAFERAGEAGCAVQ
                     VHAESGDCADMREMASSAGLDPGRVVKHYAVPSTPLVPSLIATNPAVPDLCRQGRAFM
                     MESDYMDENTRPGAVIGPRSVPRVTRKLLEAGEIDEDSAYRVHAETPSRVYGVEISL"
     gene            30259..30552
                     /locus_tag="PK679_04445"
     CDS             30259..30552
                     /locus_tag="PK679_04445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF424 domain-containing protein"
                     /protein_id="HPC55239.1"
                     /translation="MYMKVHRTPKGEEVVAVCDRELMNTTLYREGVEIHIRGEFYGDH
                     TVSADEVRKALVNADNANLMGERTVALALEMGLISRSSCLMLGDVPHAQIFRI"
     gene            30558..31598
                     /locus_tag="PK679_04450"
     CDS             30558..31598
                     /locus_tag="PK679_04450"
                     /inference="COORDINATES: protein motif:HMM:NF016842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0030674 - protein-macromolecule adaptor
                     activity [Evidence IEA];
                     GO_function: GO:0043023 - ribosomal large subunit binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="60S ribosomal export protein NMD3"
                     /protein_id="HPC55240.1"
                     /translation="MSIQDSICPLCGKPSPRGEVCGPCRVAKIQWLECPSRVQVVVCP
                     TCGARREAGTWSDMPWEAADLVGSLVRRSLVFHPELRDVDVDLAVRERSVNRSTVECT
                     IRGRLFSVPVEGSCTVEVEWKKEQCDRCSLISGSYYEGIVQVRGTGRRPSPREIEESR
                     RIADAILGSLNAAGERLAFISKWDEHRDGLDITVGSQRLGREIASGITQTLGGSVSTH
                     PKLVGEKAGKQIFRVTYSVRLPRYSRGDILVVRGKYVEVIGVEGRLFRCIDIESGTTR
                     LFREGQIERRAGRREDSTLWQVIFRDRDLLGLMDPSTGITREVLVPAKGVFPPGSGVH
                     VFFDGERPVILP"
     gene            31604..32479
                     /locus_tag="PK679_04455"
     CDS             31604..32479
                     /locus_tag="PK679_04455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HPC55241.1"
                     /translation="MMRVREVARGDLSRIRDEDWVDWSRRPFVRGDVAYVPVRDGFSF
                     SSILPDPQTCRGRGYTMIGTVAVFHGKEKPRDADVRAVEVSRKPTAVLWIPSSEGQRR
                     KPRAHVLAGTPGEVAHRECGITYFLDPSRIMFSAGNRGEKERLRKMVRPGERVADMFA
                     GIGYFSLPVAVQGAKVHAMEIDPDAFSFLVRNIGANGVADLVVPQLGDCRSCLSGTYD
                     RIIMGHFDSCLYLDCALSHVREGSVLHVHTAGDASGPIGDFLAGRGIRATVETRRVKK
                     LGPRIWHCVQDVTIG"
     gene            32476..33645
                     /gene="coaBC"
                     /locus_tag="PK679_04460"
     CDS             32476..33645
                     /gene="coaBC"
                     /locus_tag="PK679_04460"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015939 - pantothenate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HPC55242.1"
                     /translation="MMHYSPLAGKEVVLGVCGSIAAVETVRLARALQRRGACVQAVMS
                     RAACDIISPHALTYATGRPTITAISGMVEHVRHCGDGGSADLLLIAPATANTLCKIAA
                     GIDDTPVTTFATTAIGRGMPVVVAPAMHESMYRHPGVRRCLETLGEWGVVVAGPRIEE
                     ERAKIADMEEIILLCERELSGKPLSGRHVLVTSGACQERVDDVRILTTRSSGRMGQAL
                     ALQAFRLGARVTVVHSASLPLVENIRVSDAAGMGEAVRRICSTDPPDLFISAAAVSDF
                     APEPFPGKIPSGRAVTIDLHPLPKIIDEVAGHFGIPTVAFKLGRNAVAQGNAMLKGNI
                     GIVVANEPDAIGQDTASVTILSRNGPPRHVEGKKEDIAAEILSVAIGTFSLSRVT"
     gene            33738..34604
                     /locus_tag="PK679_04465"
     CDS             33738..34604
                     /locus_tag="PK679_04465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHMP kinase"
                     /protein_id="HPC55243.1"
                     /translation="MTPCASATSPGHLSGYFRPVYGPTPADTGSLGAGIVISEGVTVT
                     IRPAEETNVIVERRDPRDGRIVEVTGSSPPVEYLLSRLGVRARVRTVCFLPIGAGFGL
                     SAAALLATAVAADALFDLSLSPPERASLAHEAELAFHTGLGDVAACAGGGRDCRKGPG
                     IAASIERSFDVVEPLCALVFGPLPSPGILQSREAMERVTAAFPDRCPGDVDDFFRLSR
                     GFAEKSGLMTPEVRQALAVCDGAGIDATMTMLGNGIFAYGKEAPGLLASMGEVFLLHP
                     ADNGPRLVEVRR"
     gene            34601..35332
                     /locus_tag="PK679_04470"
     CDS             34601..35332
                     /locus_tag="PK679_04470"
                     /EC_number="6.3.2.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphopantoate--beta-alanine ligase"
                     /protein_id="HPC55244.1"
                     /translation="MIPPDHPRYRSLLARERIARYAAGGIVTLEGLAAHGRGEAFDYL
                     IGERTTESALLAERTAAALLLCAERPVISVNGNTAALAADQVARLQQVSGARVEVNLF
                     HRSEERIQKITALLEDAGVTVGKGRAERLLPLSHDRAFCLRDGIYSADTVLVPLEDGD
                     RCSALRTMGKTVIVIDLNPLSRTARTASLTIVDELTRALPHITEACGVLSREEALYLC
                     SSYDNRKFLSDALAEIQRRLARALD"
     gene            35319..36359
                     /locus_tag="PK679_04475"
     CDS             35319..36359
                     /locus_tag="PK679_04475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HPC55245.1"
                     /translation="MLWIEKYRPVSFEEIVGQERVVGRMSHFAAARSVPHMILAGPPG
                     TGKSVSVECLANALYGDFAPENLTVIPTSDLFSQGRKFLEREERYAHLYRPEESVLSN
                     FKRIIREYASLKPLDAEFKLLVFEGASSLPREAQQALRRIMERSSRTCRFVYCTCHPS
                     AIIPAIASRCLPLFFSPIPDDLVASHLRMIIDRERGPENTVGNDDLGLVVAAAHGDLR
                     KAVMLLQVLSETGRESGFRALSESETGQLALAAFSAIRNGDFPAACRRVENLMIEYGL
                     SAREVLRELSSAAKRDFNDPRIATVLGDGDANLIHGHNEFIQLNAVVVKLATIVRENQ
                     GPANSPDMQASS"
     gene            complement(36307..37677)
                     /locus_tag="PK679_04480"
     CDS             complement(36307..37677)
                     /locus_tag="PK679_04480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIR synthase-related protein"
                     /protein_id="HPC55246.1"
                     /translation="MDVEEFTRRALSSGATEREVREKLVQRIREYKPGAPDNYIEAFA
                     GAVIAEVRNTTGLSGDLFSFRESGVSMGEFGVGSRGTGDFFAHRQIARIIGKTSASVG
                     VDEMDDAGAVAIPSAGDRVPRFLVCTVDGMHSRLSDFPFLAGFHATRATLRDVYVMGA
                     RPLLLFSDIHVADNGDVAKIFDYTAGVCTVGESMGIPLVSGSTLRIGGDMVLGSRMTG
                     CVGSVGIAGHLTARREARPGDVILMTEGAGGGTIATAALYSGFPDVVKHTINLHFLQA
                     CEALLASPVLREIHAMTDVTNGGLRGDAHELAATARCRVVIDEEKVGGLVQEDVYGLL
                     EELSIDFLGVSLDSLLITVPPGAADRVAGVIRGAGVKVERVGEVVEGKPGAFLRTGGK
                     IVDFVPRFRESAYTPVKVVVDSTHRDFEEMKRAVGEAATAAMEKKERIKKMLACQGNL
                     RAPGSP"
     gene            complement(37956..38480)
                     /locus_tag="PK679_04485"
     CDS             complement(37956..38480)
                     /locus_tag="PK679_04485"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55247.1"
                     /translation="MHTSAWPVAIVILLVLVAIPANAMTSESLDISIRQDGKADIRFA
                     YHLDWLEYIAVYLRLVDPAAELKKALESNFGKPVTVISVNSNSVHLSVDSFAQVSSSN
                     GTMTARTPGLSFAAGEKILKTYWFAPLVTADLSPSVTTIRFPDGYVETFPDRIEIPPL
                     VHTWKAGEGSQVPG"
     gene            38612..38872
                     /locus_tag="PK679_04490"
     CDS             38612..38872
                     /locus_tag="PK679_04490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55248.1"
                     /translation="MRKKHLAACLLVAWVLLVIGFMILARTLDLEIFFVLWLIGILVV
                     VELASDHFATPRHLQVQKFVIAAGVVLFGAIVARKVLEILAR"
     gene            38869..40635
                     /locus_tag="PK679_04495"
     CDS             38869..40635
                     /locus_tag="PK679_04495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HPC55249.1"
                     /translation="MIRRTILAAGVLLGILCLAIAGMHAFSPLLYSPASDSRAPDHVN
                     PLALKHVTSGRSARIIPLVADIIGTPGSLVLNIRSKDFASASRDLQEYRDSLRNLDTL
                     VIQLDLDEGEIAKFRRAGRENAQILAELLNGTERWDDLKTLEVRFRESGDTAMETSVR
                     YEGETLKRKIQDLYREYLEQDDVILSTGEKFELDTSGHKKSITEFREIVNSITAGDEE
                     KEGTLAGPGDLPVFLNVSPDRASYGDTVRMEGQVKAAGSNNIGDIALFVDSARNVTLR
                     TGPDGSFSHSYRVERDRAGTHTVFAVYEGSLFSPIESFTVEVIPSFLQLGPPRVQSGK
                     VLCHGTLFAGSQPVTGAPVEIRADGKRVATAQTKDDGTFSAQVRLEPGTYSVRAQFEG
                     EGFPLLPSGSESYEVLVPVPPPAGVDGKGFFTDPLSLVVVSGFLCLSGAGAFYYLRRR
                     RHGILPARTPLPVPEMMDAPASVPVGEQVFPPAPPAETPPEPGLPLQAGDVRDVSWQE
                     LFRRLRVAVSKVASLRYPQSLTPREVCASCRDTRIREFVCRFTSGYERVMYAGGDLPR
                     EEKDRMMEAYRAVLGILGGKDH"
     gene            40667..41512
                     /locus_tag="PK679_04500"
     CDS             40667..41512
                     /locus_tag="PK679_04500"
                     /inference="COORDINATES: protein motif:HMM:NF025617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4350 domain-containing protein"
                     /protein_id="HPC55250.1"
                     /translation="MLGVVLVLLHLSATNADYSRYNPGWNGTSVLFDMIDEADGTMVT
                     DPSHLSGQGDAMLLFVAPGRKPPDEVREELRDFLSRGNCLLIASDREEDNGLLEGIGS
                     SIRIRQSDIISVDRFFDDPSSVIAFPAGDDPLSAGIPRLVGNDPSFLTGGTPVFATSL
                     LSFRDTDGDQRLGKGEVLERFTVVSRETIGNGTLYVVSDPSIFINGMLVANPPTGNRE
                     FVARILSLRPVLLAEQGYSRTAEGGPVIRVINLVKDATSIEMAAITLSMLLLGLFLAF
                     GRRDA"
     gene            41509..42477
                     /locus_tag="PK679_04505"
     CDS             41509..42477
                     /locus_tag="PK679_04505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HPC55251.1"
                     /translation="MTVPTDELAMLAGYYREIKKRMGEFIVGNESLVELCMIALLSGG
                     HLLMEGTPGTGKTSIVKTIARLTGCAFARFQCAVDSQPADILGVRIYDQEKRDFTLRK
                     GPIFSNFLLIDEINRLAPKTQSAFIEAMSERQATIDGITMPIAPPFTVIATQNPFEFE
                     GTFPLIEAQKDRFMFSMVLSQLDGDAELEIIRREHAGKLDWDSFYSQLKPVMNSELIL
                     SLVSSVARVHIDEHLLAYIRDIVVATRNHSEVHIGASSRASIALVRGCKALAALRERT
                     YVIPDDIKYLALPVLQHRIILTQEAQISSISPAGIVGDVLDRVEVP"
     gene            42481..43779
                     /locus_tag="PK679_04510"
     CDS             42481..43779
                     /locus_tag="PK679_04510"
                     /inference="COORDINATES: protein motif:HMM:NF013998.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HPC55252.1"
                     /translation="MRPSRRTVVLLIAAAVSLLLAWSLDSAPALFLAGSMSGFVAVRA
                     FLFLHAAGTVASGVRVERTATPFILRQGSPVNVTCTVHLLLPHGIRAEVSDVPPPGAP
                     LTKGSSSAEITLAGSHGMKLAYGLSCISCGRLSFGGVDIVLHDPFFSLLLPFRGGAFS
                     HPTLLVDPVGRFRAGEGSGIIGDKDSEARKLLRGYGIRSFRGYMPGDDPRTIDWKLTA
                     KHGKLFVREYAGMIGKNPLLVADLPDSAMPCPASLRDAVIGSALDAVREMCRMPRGCS
                     LMVICGPNLLSFLPNERSSARLERALREYSSPQQVLRCYRALDPAVAEAFRQRLGETE
                     GNGDGFPRKLREIYSAFIPAMEPLPFEVQCARALARQGDTALHVLSTGWGDASHLAIL
                     GLQARRRGVDARIGIPDSAISPDLLRRLKGWGYTVVRVMA"
     gene            43776..44261
                     /locus_tag="PK679_04515"
     CDS             43776..44261
                     /locus_tag="PK679_04515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55253.1"
                     /translation="MKPGMTMVMAVLAISLVAAGALFGTPLFPVALVAGALLAGSGLV
                     VVFFHPEETALFLFAQPPVFLSWYASPLLAVALEALITIAFLVSAGDTGVRRGVVSAI
                     LLVSVSGLFALFIAGHRHVLLPLVLLLVVCVIVMLALLGTASHLIHRVTGGSHEAPGR
                     Q"
     gene            44239..45051
                     /locus_tag="PK679_04520"
     CDS             44239..45051
                     /locus_tag="PK679_04520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55254.1"
                     /translation="MKLQAANDYVVSGTVLLAAAATLLVIATVTNRGDLTSATLFLCG
                     VATFLAGVFMLSFSRSEPFDAEVASLLSVPGMLNQCRICADLGVRGDAWFLPPAEGAG
                     PLREFIPVAGQDVPPVVQDFTFVTGPDTPGIVLVPAAAPLIDYCEKKFSLVIPSAEGE
                     LIAAIRELALDVLELADGVEIVRNGDSLVMTVRGYRLFSGCMVVASESPKCCSMHPCG
                     ICSLAACMLARGTGVPWQVSHVSFVEGKKQVTAILRSHPSPAPTGAGPGSSR"
     gene            complement(44984..45988)
                     /locus_tag="PK679_04525"
     CDS             complement(44984..45988)
                     /locus_tag="PK679_04525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1616 domain-containing protein"
                     /protein_id="HPC55255.1"
                     /translation="MDERSPLPPLGEVLLAFSPTDTPRDLALVYLWTVLSILSIYLPV
                     VNGSPLRVIFALPMVLFVPGYALIAALFPGKKDIDGIERIALSFGLSIAVVPLIGLVL
                     NYTPFGIRLDPVVVSLVIFTLAMAAVAQVRRAQLPPDERFTVPFRMMLGKAREELFPA
                     GSSRLDRALSFLLVAAVIAAVATTVYVIVVPKEGEKFTEFYILGREGKAADYPTDLVL
                     SRPESIIIGIGNHEYRNVTYFVEILLLDNRFDPETNTSSILSMERMASFSVTIPHNTT
                     YQQRHTFIPESREANQVKFLLFRDNLPPDTIWGQDRLNASYRDLHLWVQVKGGSGVSR
                     "
     gene            complement(45995..46945)
                     /locus_tag="PK679_04530"
     CDS             complement(45995..46945)
                     /locus_tag="PK679_04530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55256.1"
                     /translation="MGTGKENSGRFFYLSVLVLVLSLVPGAGAVAVTVTPDQIGEGDQ
                     VSIGITGLSDNSTFSLRIEGTFAVSPGGAFSFETGNLVMPFGLRDGSLSATLQNTATN
                     VLTVRKGDTEVRKVGSSQGGVFSTSETGSIPAGTYDLISLSGTAAPGADTIVAGLTLQ
                     GKKSGPDDSVITFLVQGVSGGRITVTVTVDGETALSRTIVIGDTVTPTPTATATSSGG
                     GGGGGTSGGITTSGGSGTTTTTATPTRTATPAPTLTAPAQTTAGQTPAGTGTMTTIPT
                     SPAATAAEKTSPAPTRSATCPAIAALAVSMGALVFFIRYR"
     gene            47246..>47613
                     /locus_tag="PK679_04535"
     CDS             47246..>47613
                     /locus_tag="PK679_04535"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55257.1"
                     /translation="MEVTNRGTIHPSGKRGASPRISGSGKSLIISWLVVAMVLAMVAI
                     PACSAAPPPFARLDLNQTQTYRNLTISSLETVDLMDLSVSRVTLHSTVGDDSDTKTIP
                     FPGIRDIRRVFSSDTASWHG"
     assembly_gap    47614..47713
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <47714..50148
                     /locus_tag="PK679_04540"
     CDS             <47714..50148
                     /locus_tag="PK679_04540"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55258.1"
                     /translation="ETYDATIRVNMTALGEVGGSISPEHILSGNPFLTILRETGLGPD
                     DFKKVVSYSIFAVGNSTPPHSTHFSKINITPGFGTSGYALHASQVTIPSSDLRGLLDG
                     TFSLYALGADSNNTVVALDHDTIRLGSSPLANFTASPTEGPAPLDVHFTDLSSGTSPM
                     TYQWIFDDGDTSDDQNPTHLYTEAGTYTVTLTVTNDFGSSTEQKVHYINVTAPGPTPT
                     PTPTPSPTPSPTPPPLQADFTADPTAGFVPLMVQFTDTSTGAHDTWSWSFGDGGTSTA
                     QNPSHTYTSVGTYTVSLTVRQGTGTPSTKTRTNYITVVAVPPPPVAQFAANVTSGPVP
                     LTVQFNDLSSGSIFEWVWTFGDGGTSTERNPVHTYTTPGNYTVSLRVRGLGGIDTETK
                     TNYISAFGVPPVASFIANVTSGEAPLPVLFSDLSTGGPTAWSWTFGDGGFSTMQNPVH
                     VYHYAGNYTVTLTVANDYGTNTMVRTRYINVTGLTPPPPGLHADFAGAPRSGFIPLTV
                     LFADASTGEPTSWNWSFGDGTYSDEQNPVHIYSDAGGFTVSLTVSNGTASDTVTRTDY
                     IIASRRGGGGGGGGGGGGGGAYIITGTPTPTPTATPTPAVTPAGPLPLGPDGRTTQPV
                     TIVSSDGRAALSIGTGVAVTCEEGLPPTTIGISPISGQDLPALPGDPAFMGYAYAVSP
                     DCTLLDPGAILSLQFTSEEWTDLASRDLVLMRFNPATRTWIPLPTTVDQGRHTVSAPI
                     THGGIYGLFAWAPKGTPVPAETTVVPTTPAGPEIPVTLVAIVIVVVVVAAGAAVYLLK
                     IRPGRGNPPASP"
     gene            complement(50312..51133)
                     /locus_tag="PK679_04545"
     CDS             complement(50312..51133)
                     /locus_tag="PK679_04545"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55259.1"
                     /translation="MDTMTSRDLGLFFVILTASFLLLVPAALAQNEPLMPHLFYGQAY
                     IGGTPAPAGTPVEAWCPGIVNGTAGNPLITGEGGTFGGPGSFDEKLIVSGTMPAGTPI
                     IFYVGGTRALCREIGSTSAFSESIPFEPSQYTGIELQAGTGSGAVPATSGTTPVTPTA
                     TTGSSAGSTGSGGAGTGEESAPVSSQTAVMTTPTPGTAVVTGTPAGSSEVYQPSMEPV
                     TPLTRAESGVGPADNSIQGTPAEKPRQAGPEPVLQGVVCILGAFSVALLTKRTRP"
     gene            51487..51963
                     /locus_tag="PK679_04550"
     CDS             51487..51963
                     /locus_tag="PK679_04550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55260.1"
                     /translation="MKREMDGSLDRSFRLVPTAAGLQPVALQAEKREDREQDMTPPDC
                     FFTSLAPFYPAVMPDSPMIFPDVSGLILVLLSLRFRGIQEIGSPLLGLPGSLFHPEYP
                     DEPSRAEVVDQPARRRDLDFRDGPVEGFIGIHQPVGLEAGDPEPGEGADQLQVLDA"
     gene            52076..52243
                     /locus_tag="PK679_04555"
     CDS             52076..52243
                     /locus_tag="PK679_04555"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55261.1"
                     /translation="MQKSTGTMAVPSVKRVVIRLIPYASRWYFPLQCRLTTFIRWFVE
                     SIVVDDQDSLL"
     gene            52628..>55277
                     /locus_tag="PK679_04560"
     CDS             52628..>55277
                     /locus_tag="PK679_04560"
                     /inference="COORDINATES: protein motif:HMM:NF012311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HPC55262.1"
                     /translation="MILLSCWIGPVSAEIPATSDYEPGVLIICFTPEIAGNPGSLSQV
                     AERLHGGINSTILEDSEDLGIPGVQYIALDPDVTVEDAISYYLSDPSILWTEPNYIVH
                     IPDPVDGTTPGETTPLKMSDMHAGFTSFRSIPSSLASYPNDPDFSLQWNLKKIQVPEA
                     WETGAGQGTVVIAVIDTGIDFSNPDFDNRIWTNPGEIPGNGIDDDNNGFIDDVHGWDF
                     ANGDNDPGDDEGHGTAVSSVIAARVDNKVGIAGVMPDVRIMPLKAGNKNGILYSKDIA
                     KSIRYARENGARIVVCSFGKYMPDTLERTQIQKSDSLLFVCAAGNEGNNNDARPFYPA
                     GYPSANIISVAATDNGDFLCPWSNYGQSTVHVGAPGLDIPVYTLASARVTVSGTSFAA
                     PHVAGLAGMVLSKDPTLSVAQLKGLILNNVDSGPLSGYTITGGRVNAFRTVRGLQLPP
                     AASFTATPTSGTVPLTVQFTDTSTGNPGSWSWNFGDGTTSAEQNPLHTYHKPGTYSVS
                     LRVTTRDGGFRTLKPFLVKVQEADSLPVPTPLPTTVLPTVTPTEAAAPPVADFSASPS
                     FGPAPLSVRFTDISTGNPASWSWNFGDGTTSAEQNPTHTYTTPGTYTVSLRITTDSGG
                     FRVVKSGLISVGKPTGDARAAAPSVRSAGSGIPDDVLPPGTDTDPGPLNPDFVAYLES
                     RTQGRQEEGGAYTGLIPFPINLSPLKGQHLDFPDSTVASLPSRYDLREHNRVTPVKNQ
                     GSCGSCWAFAIYGSLESVIKSRTGTEWDFAENHLKNTHDFDKGPCDGGNSDMSMAYLA
                     RWSGPINETDDPYNPSSPSPVSPPGLSPVMHLQDAYIVPPRDGSLDNENIKRSIMEYG
                     GVYSSFWYQDGFYSENTHSYYYNGSNK"
     assembly_gap    55278..55287
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(55328..55645)
                     /locus_tag="PK679_04565"
     CDS             complement(55328..55645)
                     /locus_tag="PK679_04565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55263.1"
                     /translation="MVILVNVIVRVQGGGIEGAIRIIISIKGSSHRSFLSKRCIIIGN
                     PEIAIISPPCSPAVLCQECTVSWRWVPEVGSGIIIIPAHDGYGMVTIIRCEYSSLWKI
                     IIV"
     gene            55553..>56254
                     /locus_tag="PK679_04570"
     CDS             55553..>56254
                     /locus_tag="PK679_04570"
                     /inference="COORDINATES: protein motif:HMM:NF037272.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin like domain-containing protein"
                     /protein_id="HPC55264.1"
                     /translation="MGTPLNRYYDPNSAFNSSPLDTYDYIYQYDHLGWTNADGYNTDT
                     AWYANIFTATRNEELSAVGTYVYSPGSQYELTIFKFPSANDPWGTPVSHKTGTIDIPG
                     YRTIPLDNAVLLWPGYRFSVVLKLTTPNWTYPVPLEMPIPGYSSKATASRGQSYMSKD
                     GVIWTDVVDRYSNTNVCLKAYTRRIAPPVAGFTATPEEGPAPLVVQFTDTSTGNPTVW
                     SWDFGDGMKSAERNPR"
BASE COUNT        11390 a        16999 c        15974 g        11681 t
ORIGIN      
        1 aagacgacac tccggggacc ttcaatcacg tcgtccgtga cttcctgccc ccggtgggcc
       61 gggagacagt gcatgaaaat tgcgtcaggt gctgcgaggt ccatcaactc cgcgttgatg
      121 gtatatcccg agaacgcccg gagccttgca tcacgctcct cttccgtgcc catcgagacc
      181 caggtatcgg tcacgaccac gtgtgcgtcc ctgacagcct cacgcgggtc actgagcacc
      241 ctcacccggc cacccccggc ccgggccctg ccgaggatct cttcaggagg ctggaaacgg
      301 gggggtgtcg caacggtgac ctccatcccg gtgagggccg acgagaggat cagcgagttg
      361 cacacgttgt caccgtcccc gacccacccg accctgatgc cttcagtctt cgtaaaatgc
      421 tccctgatcg tcatgatgtc ggcaaggatc tggcagggat gttccaggtc ggaaagcccg
      481 ttgatgaccg ggatggtcgc ataccgggcg aactcctcga tggtggaatg ccggtatgca
      541 cggatcatca cgcccgagac gtaccgcgat gccacccgtg ccgtatcgcg gatttcctcc
      601 ccccttccga tctggaggtc atggacactc aaaaagagcg ctgttccccc cagttcagcc
      661 atcccgacct cgaaagagat ccgggtgcgt gtcgatgatt tctcgaagat catggcgagg
      721 gttttgccag gcaggcaccg gtgcggcttt cctgccctcc gcatctcctt catccgggca
      781 gccatatcaa ggagatggtc cagttcaccg gctgtaatgt cgaggatcga gatcaggtcg
      841 cgcttcatcg gagttccctc atgtgtgata tccggcgttc gaggagttcc tgagtcccga
      901 tgtccctccg gtgcctcacc ctccccctca cattcgaagc cgcggtctcg gcaatcctct
      961 cggccagagg gagcgtgtcg ccgagaccaa cgaatgccag cgtccgcgaa gaacgtgtat
     1021 acagtgtccc gtctctctcc tcgacgtttg catagtaaag gatggctggc tcgtatggtc
     1081 cgatggtcag gggttctccc gttaccgggg cctcgggata accctcgggc acgatgtact
     1141 tgcagaccgt ggctttccgg gagaaccgga ccggcatgtt cccgagggtt ccatccacaa
     1201 tccgctccat gatgctgaaa aggtccgtct cgaggagtga gagcacgttc atcgcctcgg
     1261 gatcgccgaa gcgtgcgttg aactcgatca ccatcgggcc atccctcgtg ttcatgaact
     1321 ggccatacag gatcccgcga tagggtgtcc ctgcattctc cattgccgcg acagcagatc
     1381 gcatgatatc cagtgccctc tccctgtcgc tcccggttac aaaggggagg gtatggtccg
     1441 ggagtgaata ggagcccatt ccaccggtat tggggccctg gtcaccctcg tatgcccttt
     1501 tatggtcctg gacgaggggc atcgggatga tgtttttccc gtcagagaac gcctggagcg
     1561 tgaactcttc cccgagcagt ctttcctcga gaacgactcc gccctgcagg ccgcggatgt
     1621 actcctcagc ccctttccga tcgacgtgtt cccctacgat cctgacgcct tttccgcctg
     1681 taagccctgt cggcttgatg gcaaggtcgc cgggatattc tttcaggaaa ctgattgcgt
     1741 cttctgcagt gcggaatgca cggtagcgcg ggcacccggc gatcccgtga ctctccatca
     1801 tcttcctgca gaacgccttg tctgtctcga gccgggcggc agcacgggtc ggcccgacgc
     1861 agggaatgcc cgccttttcg aggctgtcga ccacccctgc ctcgaggggc gcttcgggtc
     1921 cgattattgc ataatccagt gagttctgct gtgcgaaccg tgtgacggca gcaacatccg
     1981 tctctttccc gatggagaac ttccggcaaa gctttgcaat gccggggttc tgctgcgcca
     2041 tcacggcgta caggtccaca tcgctgttgc gggacagcgc catggcaatg gcatgttccc
     2101 tgccaccacc ccccacaacc aggattttca tagtcatgta tcgtaaccgc gtctgttaac
     2161 gcttgctatt ctcgcgtcct gcattgagga tttcggatgc cttcgcaagg gcctccagtc
     2221 gcacgccctc gcgtccgagg ctctccaccg cgcccgcttc cctgtcgacc acgacaacgg
     2281 cggtatcgat aattcccccc gcctcccgca gtgcccttat cccctggatg gccgaccctc
     2341 cggaggttgt cacgtcttcc acgaggagga cacgcctgcc gcttacatcg ccgatcaccc
     2401 tgcctgattt tccgtgccct ttctcctggc tgcgcacaat tgcaaagggt tttttgctct
     2461 cgagcgagac ggcaaccgcg agggggacac ccccgacagc gacaccggca acggtatcga
     2521 actcaaacct gcgtgcaatc agcgctgcga tcaattgcaa tgcctccggt ctcgtcacca
     2581 ccttcttgat atcaaggtaa taggagctct tctcacctga cgcgaggacg aattccccga
     2641 attcgagtgc cccgtaacgg agcaggagtt gcacgatctc gtttaccatg gtacgtcttt
     2701 tactcccgta atgaaaccaa tcacgttggc catcttgtgc agcaggggcg tgaggaccag
     2761 tatccagaag agcaccggga gcgtgaccgc tccgagaagc caggcaggat caaagagtgc
     2821 aagaagaagg aaagcccctg caacgagatc atactggtct gcgaccggcc atttcccgcc
     2881 gctcgggatc ttcaggcggc gcttgaagaa gctcttgaga agatctccga gcagtgcccc
     2941 gacagcaagc aatagcaccg aaaggggggt ctgggccggg agaaaggaca aatcgaggga
     3001 tccctggagc gccatctgga caaggccgac gattatccct ccggcaacgc ctgcaaagaa
     3061 acccctgtat gtcttgccat cgccaaagat ccgcgtcccg tcggataatg tcctccctcc
     3121 gtcgattggc cgtccgcccc cgaagcatgc tgccaccgag ttgggcacat atgccggcag
     3181 catgcaccat aacgcagcaa ccagtgctat tatgaaggaa tcgagactaa taatatgctc
     3241 tccaggtact gtgataaagc gtaattataa gcattaagat atcccaaaaa ttatcaatct
     3301 gacggtggat tggtgtcatg ccggcaatac tcaagaagac caggagcctc tgcccgaaat
     3361 gcaacgcggt gctcgatgca acaatcctgg aagacggggg gaaagtctgg ctcgagcgca
     3421 cctgcccgga gcacggtcat ttccgtgact tgtactggtc tgatgcagaa ctgtggaaga
     3481 agttcgagag gttcgaatcg atagggaagg ggatcgagaa cccgcaccgg gatgcccctc
     3541 cggatggctg cccctcctac tgcgggatat gcaccaacca caagtctgcg accctgcttg
     3601 caaacattga cctgacgaac cggtgtaacc tcaactgcga cttctgcttt gcgaatgccc
     3661 gggcctgcgg ttacatctac gaacccacgt tcgaccaggt catggcgatg ctccggctcc
     3721 tccgcgagga aaaacccgtc ccgacacccg ctgtccagtt ttccggcgga gagcccacga
     3781 tgagggatga cctgccccgg atcatctctg cggcaaagga tatggggttt ccacaggtac
     3841 agatagcaac aaacggtctc aagatcgccc gggatatatc gtatctccgc gagttgaagg
     3901 acgcgggact gtcaaccctt tacctgcatt tcgatggcgt cacgaaggag accaatttca
     3961 agatcgaaac agacaagaag gtcgtcggga actgcgagga actcgggatc gggatcgtcc
     4021 tcgtcccgac aatcatcaag ggacgaaacg accacgaggt tggtgcgatc atccggtttg
     4081 cagcagacca tatcagggtc gtgaggggcg tcaatttcca gccgatagca tttaccgggg
     4141 cagcgagcga ggaagacgtg gcccgcgaga ggataacaat accagagctt ctccaggata
     4201 tcgagagcca gacaagcggg attatcaaga aagacgattt ctaccctgtt ccctgcgttg
     4261 tccccatctc ggatttcgtc gaagccttca cgggaaaacc ccagattcgg ttcacggcac
     4321 accagcactg cggggctgcg acatacgttt ttgtcaatga cgacgggctg acccctgtca
     4381 accggatggt cgacgtcgag aacttcctct cggccctcaa cgagaccgcg gaaaaactga
     4441 aaaaaggtgg tttcctcatg aagtaccgcg ccctgttcga gaccatctcc cagctcaacc
     4501 attccgttaa gaaagacgag tacaagaccg gacgtgacct ctggaagctc ctcggaaaga
     4561 cactcatatt ccataatttc gacgcgctcc gcgagttcca ctggaatgca ctttttgtcg
     4621 ggaccatgca cttcatggac cggtacaatt acgacctctc ccgcgtccag cgctgctgta
     4681 tccattacgc gacaccggac ggaatcctca tcccgttctg cacctataac agcggtcccg
     4741 tgtacaggga agttgtctgg aagaagtgga gcaaaccgct cgatacctga gcacactgct
     4801 gaacgataca ggattccttt tccccttttt ttggggggaa cccggggttt ccagctgtta
     4861 tatgccctgt aagctatccc aatccccgac agttccggaa cgccggttga atgctaaaga
     4921 aacggcaggt cgattgcctc tgccgaaccc atcgcgatgg cagcgatagc aaggtcctgg
     4981 atggcaaggc ctgttgagtc aaagacggta atctcgtccg ggctcttccg gccttttctg
     5041 ccgatgacaa cctctcccag ggttcctgca atgcgcccgg ggtcaaagag accttttgca
     5101 atggggacgt tgatttcgcc cgagtggatc gcctgtgcag ggtcatccac gaaaaccgtc
     5161 gctctccgga ggatcgcggg gtcgagttcc tgcttgcccg gtgcatctgc accgattgcg
     5221 ttgatgtgcg ttcccccgga tatccaacgg tccatgacca gcggttcccg ggatggtgtt
     5281 gtcgtgacaa ggatatcgca gtcgcagacc gttttgagat cttcgctccg gcactccggc
     5341 aagagagtgt cttcgcagaa cttttcggca ttcgccctgt tcctgctcca tacgagtact
     5401 tcggtgatgg aaagttcctg cccgatcgcc atgacctgtg cacgggcctg ccgccctgaa
     5461 ccgacaagcc cgagccggac cttccgcttc ggcgaaaggt actttgcagc gactgcccct
     5521 gcggcccccg tccggatatc ggtcagaccc gttgcattca gtatggactc cgggcgcccc
     5581 gtctccacgt cgagaatgac cgtgagcgcc atgaccgtgg gaaggccgag ggaaggatta
     5641 cccgggtgaa cattgacgat cttcacgccg gcaataccaa gggacgggat gtatgccggc
     5701 atcgtcctga aatccccctt ttcgagagtc acgtagagct tggggggcat ctgcacgtgt
     5761 ccccgcgcgt gctctgcaaa ggcctcctcg atggcgcggt ttacgcgccg gagatcgata
     5821 tcccttgccg ggtcgggata gtaccgcata ccggaaaaat atggtacaga ccggaaaaga
     5881 atgtaacgcc ccttttcacg aaccacttcc acgaaggata caaagcacac ttaatacacc
     5941 tgcagtccca aatactgcca ctgcacaatc ttctgggaga cccatgatcc atatcatccc
     6001 caaaccgacc gatacccccg gtgacaactc gacatcaatg gtcgcccgcg agataacgag
     6061 gcggggcggg gactacgcgc tcatcgatcc ggcagatatc gatcccttta cgacgggact
     6121 atccgactcg ctcatatggg tttgcgggct tgcccaggac gaggtccagt tcgaggtcat
     6181 caacgcgcta tccgtggata acagggtcat caattctccc cttgcaatat tcacctgtgc
     6241 aagcaaggtc ctgacaagca ccctcctcgt gcggcgcggt atcccgacac cggaaacctg
     6301 ctttacccag tcccgggaga ccgcggctgc ttttctctcc cggcacaaga aggtcgtttc
     6361 aaagcccgta tacggctacg acgggcatgg aatcattctc gtgcagtcac cccgggacct
     6421 tgggccgcct ccctactacc tgcaggaatt tgtcccaaac gacagggatt tccgcgtctt
     6481 cgtcatcgac ggggaggccg tgggggcgat cgagcgggtt tccgacacgc tcgcccataa
     6541 cattcaccag ggaggtacag gaaggcccgt tctgatcgat tccctgatgg cagaccgtgc
     6601 tgtcgccgct gcacgtgccg tcggggtgga ttacgggggt gtcgatcttc tccgccgggg
     6661 agacgattac tgcgtcctcg aggtgaacgg caccccgaac tggcactgca tgggggttaa
     6721 tattcccgga ctcctggcag agtacctcct cgaacaggag agaatgggac gaaagtaact
     6781 ggtcctgcca gacgggtgca gaaaaaaagg ttattgaacg tattccattt ccttcagtgt
     6841 ctttgcggca agctccctca tccgtgccga tatccttccg gacgcagaga actcgacctc
     6901 cttcatcgca tctgcaagct cgttgccgag gacgaagatg gcatacttgt gttccatctt
     6961 gctcttgtgc agttgcgacg ggttaatttt gagtgagtaa tagttgctga acttcaggtc
     7021 cgagttgatc gactcgaagt agtccttgat ctcagagagc atctggtgaa gcgtgatcag
     7081 ttcctccttg tgcatacact cacttccaga aaggagaata tgcgtggagg ggataaatag
     7141 ataactccgg gaaaaaaatc aggtgatttt aaggagcctc atggagagag ggcgcttgat
     7201 tatgcccttg taccccctgg ctgcgacata ttcaaacccc tttccgacca tgcggtcgat
     7261 catcttctgg gtcacctcgc cgtcgatgac aagtccgcgt gcgttcccgt tcagctcctc
     7321 gagggtccgc tcgacgtcgt caagtttcac ttcccgcagg accgtgtact cagacgagag
     7381 aaaacgtgcc atgcgctgtc ccctcacctc ggagaggtgc tctgaaagtg tccggggacc
     7441 tgtcttctct gccgctgaag cctggtgtgc ctttggctca cgtttcttcc gctggaccgc
     7501 cccctccccg gccggggcgc cctcgtcggg aactcctgca ggattaagct gcggggtctt
     7561 ttcgtcgtcc tcctccccga ccggctcctc gcggacgtaa tcggccggga tcttgttcct
     7621 gagggccttg acgatctctt tccgggagag gtcctcgaca ctctttccgc ggggtgcata
     7681 agcgacaaag tcgatctcag caacctggag gagctcgcgc aggatcaggt ctccacccct
     7741 gtctccgtcg aagaaggctg tagctgtctt cttctcgcag agctcgatga tggtgcgcgg
     7801 gatccgggac ccttccacgg ccaccgcgtt tttgatgccg aaccggagga ggttgagcac
     7861 gtctgccctc ccctcgacga tgatgatcgc atccgattcg aggacgttgg gaccggcagg
     7921 gagcttgtct tccccgaccg ttccgatctt ctccatcctc atgctctcgc gaacctcgtc
     7981 gattaagagg gtgctgtcaa tcgatccatc ctcgaaagca tccaggagca gttccttggc
     8041 acgggcaacg acctgcttcc gtttgctgac gcggatatcc tcgatcgatt cgacgcggac
     8101 ctttgcagcg cagggaccca cccgatcgat cgtctcgaag gatgctgcaa ggattgccgt
     8161 ctctgccctg tcaagggacg aagctatgta tatctccccc ttcgtctccc ccttcttact
     8221 ggtgacctgg acatctatcc ttccaagccg ccctgtcctc tgcaagtcac gcaggtcgag
     8281 gtcttcgccg agtaaacctt cagtctggcc gaaaatggcc cccactacgt caggtttctc
     8341 gaccaccccc tctgcgtcga ggtgaatatg aattaagtac ttcgtggtat cgctggagta
     8401 cattcactcc actccgtgaa tcatgacgtg tcacgtaacg tctgccatgt gagaatcctg
     8461 catcagtcat gtgacaaata tacgttatat tttatatgat atgaatatat tttttcagaa
     8521 cgcccggctg gcaggaaatg tcttcacccg gaactcccgt ggcccgagag gatcgcaagg
     8581 accttctcct ggtccaggcc ctcgacgagc acccttttcc tgtgcgacga tgcccccgag
     8641 agaatcctga cccgggacga agggagggag aataactgcg agatgacctt cacgatttcc
     8701 tcgttggccc ttccaccctc cggcggttct cgtaccagaa aaacaatgct ctttctccag
     8761 gcattatacc catgcggaaa agcagtttcc tttgctccgg ctgtcacatc gagtgcgatg
     8821 accgtgcctt tgcgggtcgg tgtgagggcg cccctgtaat catccataca gaaaacaggt
     8881 tatgtcgccc ggcattaaca actgcggatc atcggtggca tgctgccgtc cctcccccgt
     8941 tttacccatt accgggcggt gcctgtcgca cgaccgggtt gtcccgtggt tcacccccag
     9001 gcatcccgcc agatggtccc ccggggacct atggccgtgc tgaatcggca ccattttctc
     9061 tctgcgtgcc gtgtatatat ccccttccca tgaaccaccg cggtctgccc gtcccgaatg
     9121 ccccgttcct gtaaacgata tccccggcca tgacaaccgt ttcggggaat attgcaggca
     9181 ttccctcgaa gggagtccac cctgcccgcg agtggagttc gtcggcaatg attctggact
     9241 cgtgcctcgg gtaaaccgca aagtccgccc tgtcgccgac cgaaaaaccg gcagggggta
     9301 tgcccaggat gcgggcaggg ttgagattcg tcttctccac gagtgtcgaa agggagatct
     9361 ttttcctccg gcaggcagca agtgcaagcg ggaccatcgt ctccacaccg gggatacctg
     9421 ccggtgcgtc ggggaatggc tgttccttgt cctgcacggt gtggggggca tggtcggatg
     9481 caaggacatc gatcctttcc cagacggacc agagttccct cctgaccact tccggcctca
     9541 gggggggatt gaccttcccg cgggggtccc ttgcagcaaa gtcatcgagg gcgagaaaga
     9601 ggtgatgcgg ggttacctcg actgtcgcgt cccctgcacg aagaacggaa acggcggaac
     9661 tcaggtggca gaaatggagc ctgcatccct tccggttcat tttcctgacg tcttccacca
     9721 cgcgtgcttc gccatcgggt gaccggatgg catggtggga acgcaggtcc cggtcatctc
     9781 cccttcccac ctcctctgcg tggatggtgc agagcccccc gatggctcca accgagtcaa
     9841 gaaccatcgc taattcagcg ggtgtcagcc cggagccata actggaggca gcagtgaata
     9901 cctcgccgaa tgccatcgcc cctgcagacc agagcgggga ggggtctgtt cccggcacga
     9961 caccggcatt gatggcaaag tgacagagtg acccttcccg tgcttccctg acccgctcgg
    10021 aaaacgattc aggcgtgttg agcgggggaa cagtattcgg ctggtcaacg acgaccgtga
    10081 cccccccggc aagggcactc ctgcttccgc tcgtccagtc ctccttctcc ttctgggacc
    10141 ttccccgcat gtggacgtgc atgtcgattg cccccggaag gacgatcttt cccctgcagg
    10201 ggaccacctg ggatgaagca agagcggcac ccacgtggca gaccctgccg tccctgatcg
    10261 agatatcggc gacccttccg ccggggagga gaacgtcacg gaggacgagg tcacatgcgt
    10321 gaggggcggg tgtcatttga aagagattcc acacgataac agatgatact ttagttccgc
    10381 gcccgggaag atgtgactat tctcctcctt ttttccggca gggaaccatg caggatcgcg
    10441 agggagcccc ggcccctgca aagacggacc gggcaaatgt taatgatagc cgctgctgat
    10501 ttccatccgg aatttattcc agagtgagtt gacaccatga aaccggttat gaccatcatt
    10561 ctcgtatcga tcctgttatt cctggtcact cttcccgcag gggcagaaga gaccctcccc
    10621 ggcaccgtga cacccgcaga gacacaggct gtcaccgaag cagtaaccct tccgggatcc
    10681 atcggagggg atgtcggtta cttctccatc gactcggtgc catcgggggc cgacgtgata
    10741 ttcgacggga agtacctcgg cgagaccccg atcgttgcag aagtctacac gacagcctct
    10801 ccgtcgcata ccatttccgt cagcaggcag ggctacaaga cctggatcca gacctactcc
    10861 cggaaccccg cggcaggcca gacgattgag gtcactgcaa atctcgaacc tgttgtccag
    10921 acaggctcca tccaggtgac ctcttcccct gccggcgcaa ttgcacggct cgacgggggc
    10981 gaaacactcg tgacgccggg cacgttccgg tatgttcctc ccggttacca caccgtggaa
    11041 cttgcactct acggctactt cccttacagc acatcggtca acgtggctgc cggcgggaca
    11101 tcgagcgtga gtgcctcgct ctctcccatg cagacgaccg ggtccctccg ggtcacatcg
    11161 tcgccttcgg gtgccgaaat ctatgtcgac gagatctaca ggggatatac accgctgaca
    11221 atcggctcgc tttccacggg acggcatgaa gtccgcctcc acctctcggg ctaccaggac
    11281 tatacgcgta ccgtagaaat tgagagcgga agccagtctt cattttccgt gacgctcacc
    11341 ccggtctacc agccgaccac aggggatatc gtcgtgacat cggtcccgga cggtgctgcc
    11401 atttacctcg acgggaatta ccgtggtacg acgaacgaga gaaacccctt cgatatcacg
    11461 ggagtcgcac ccggtaccca cacggttacc cttctgaaga acaggtataa ggactattct
    11521 gcagatgtaa cggttctggc cggaaagacg gtcaccgtct ctgcagtact gacccccggt
    11581 tctgtcaccc cgtccacggg ggatgtatcc gtcgagtcct cgccgtcggg agcagaagtg
    11641 tacctcgata acgcctacga gggttttgca cctctcacca tccataacgt cccggcaggc
    11701 tcccatgttg tcatgctccg gatgagcgga taccaggatt tccagtatac agtccaggtg
    11761 agcgggggtc agactgcatc cgtcatcggc ggacttacgc cggttcccac cacggtcccc
    11821 acgaaatccc ccctctctcc tgctgtggcc gtcctgggag tcctggcagg ccttgccctc
    11881 ctgtatgtgg ggagagagta gggaaaaccc gatcattttt cttttaaaaa agaagaccca
    11941 gatgcgaggg atgggatttg aacccaagaa ctcctgcgag actagaccct gaatctagcg
    12001 ccgttgacct ggcttggcta ccctcgctcc tcctactttt tggtcgcccg ggaaaataaa
    12061 gatgtggtaa aaccggatga accccggact atcccgttcc ttctttcccg ccggacaggt
    12121 tttcctggcc cgattttgcc ctcatctccc tctccctgag gacgttcctc cgtatcttgc
    12181 ctgaaattgt cttgggcagg tcatccacga actcgattgc ccgcggatac ttgtaggggg
    12241 cagtgatttt cttcacgaac ttctgaatat cctttgccag ctggtcggtg ggttggtagc
    12301 catccttcag aacgatgaat gccttgacga tcatgccgcg gatgacgtcc ggtgacccga
    12361 tgactgcggc ctccttgacg gcggggtgct cgagcagggc agactcgacc tcgaatggtc
    12421 cgatgcggta gcccgagctc ttgatcacgt catcgtccct cccgacgaac cagaagtacc
    12481 cgtcatcgtc cctgtatgcc ttgtccccgg tgtaatagta gtcaccgaca aaaacggcag
    12541 aagttgcctc cttgtcgtaa aggtagccct cgaagagtcc caccggacgc ggtttcaccc
    12601 tgatggcgat cctccccacc tcgcccggcg gaacgggttt tccttcctcg tcatggagct
    12661 ctatgtgcca tccgggtgcg ggctttccca tcgacccggg ctttggttcc atgcagggaa
    12721 aagtcccgat gacaagcacg agttcagtct gcccgtatcc ctcgtaaatc tggagacccg
    12781 tcccctcttt ccagacccgg atgacctcgg ggttgagcgg ttctcccgca ctcacgcagt
    12841 ggcgcagttc cttgaggtcg tacttcttga ggtctgcgag gatcagcatg cggtagaccg
    12901 tcggcggtgc gcagaaaacc gtcacctcgt acttctcgag gatgggcagg agctcggttg
    12961 ccttgaactt accacggata tcgtacacga ggatgcaggc cccctggatc cacggtccga
    13021 aaaacttgcc ccatgaagac ttggcccacc ctgtgtctgc aagggtgaaa tggaggtcgt
    13081 tttcagtcag gtccagccag aaccgcccgg ttgtcacgtg cccgagggga agggcatggt
    13141 tgtgcaggac catcttgggc tcgccggtcg tcccggacgt aaagtagatg acgagcgggt
    13201 ccgtagcctt cgtcctttcc atgcccgtca tggaaacaag cttccgcgag accggggcag
    13261 ggtattcctg ttcaaccgtg tagctgatcc atccgggcag ctcggcatcg gtaacgaggc
    13321 gggactggag cgtcgggcag ctgctgcata tctcctcgat ttttccggca ttctcccggt
    13381 cggtgatcac catcctgatc tttgcggcat tgatacggta cttgagatcc tttggtgtga
    13441 gcatcgtcgg acagggacag aagactgcgc cgagcttgat gcaggccagt gcaaatatcc
    13501 accactcggg gacccgtggg agcatgatga tgacacggtc ccccttcttg ataccgtact
    13561 tgaggagcat gttggcggca gaattcgaga ggttcatcag ctggcggaac gtgaacgtct
    13621 tttctttccc ctcctggttc acccagatca ttgccagccg gttccggtcc ttctccgcaa
    13681 tcctgtcgat gacgtcaaat gcaaaattgt agtactccgg cacttccagg gaaaaatggt
    13741 cgtaaacctc ctggtaattg tgcatattgt gctccgcggc agccatatga accagatcat
    13801 gggggcagat gaatcattaa ggtgtctttt tttctccggg agagactctg ctgcatccgt
    13861 ttctcccccg gaccctgtta tcatgaagac ctggagaaga aaacgagggc tggggagggc
    13921 tgggtatgaa aaaaaaggag ggatcgttca gtgcgagttg ttgaactttt ccatctccat
    13981 cctgcgcagt tcgttccgct ttatctttcc cgagagtgtc tttggcaggt caggaacgaa
    14041 ctcgatggca cggggatact tgtaaggcgc ggtattcttc cggacaaacg cctgtatatc
    14101 cttcacaagc ctctccgacg gttcgaatcc cggcttgagg acgatgaaag ccttcacgat
    14161 cgtcccccgg atgaggtcag gggaaccgac gacggccgat tctgcaactg ccgggtgttc
    14221 gaggagcgcg gactcgacct cgaagggacc gatacggtat cccgagctct tgatgatatc
    14281 atcgtcgcgg ccgacgaacc agaaatatcc ttcctcgtcc atgaatgcct tgtcacccgt
    14341 gtagtaaaag ccgttgacaa aggattcggc atttgcctgg tcgttatcga ggtacccgac
    14401 gaacaggccc acggggcggg gatcgagtct gattgcaatc cggcccacct ctccctgggc
    14461 aacgggtctc ccctcatcgt catggagctc gatctgccac ccgggtgccg gttttcccat
    14521 cgagcccggt ttcaccttca tatcccggaa cgtcccgatg cagcagactg tctcggtctg
    14581 gccataccct tcggcaatag ggagtcccgt accctcctgc cacacccgca cgacctcggg
    14641 attgagcggt tcccctgcac tcacgcaccg gcggagctcg cggaggtcga acttctcgag
    14701 atcggcaagg atcagcatgc ggtagatggt cggcgggacg cagaacgttg tgatctcgta
    14761 cttttccatc agcgggagga gctcggttgc cttgaacttg ccacgtgcat cgtagatgaa
    14821 caggcatgcg ccgattatcc actggccgaa tatctttccc cacgcgcact ttgcccaccc
    14881 ggtatccgag tacgtgaagt ggacgtcgtg gggagtcagg tcctgccaga gcccggccgt
    14941 gacgaggtgc ccgagggggt aggagtggtc atgcaggacc atcttgggct cgccggttgt
    15001 ccctgacgtg aaatatatga gcatcgggtc ggaggatagc gtcttcttcc cgacaggcat
    15061 gctcaccgaa tggtgggaca cgggggcagg atagtgcagt tcgacagggt aactgatcca
    15121 tcccggcagc tcgccgtcga ccaggaaccg gcacgtaagg gagggacagt cgtcggcaac
    15181 ctcgttgacc ttctccacat gttccttgat tgtaatgacc atcttgaact tcccggcatt
    15241 cagacggtac ctgatgtcct ttggggtgag catcgtcggg cagggacaga ccactgcacc
    15301 aagcttgatc agtgctatca tgaaaaccca ccactccggg atgcggggca tgatgaggag
    15361 gacgcggtca cccttctgga taccgtactt gatcaggatg tttgctgcct ggttcgagag
    15421 atttttcagg tcacggaagg agtatttctt ctcgcatccc tcctggttga cccatatcat
    15481 cgcgagcttg ttcctgtctt tttgtgccca tgaatcgata acatcgtagc caaagttgta
    15541 gtaccggggg actgtgatcg aaaagttcct gcaaaggtcc tcgtaatccc cttttgctgc
    15601 cgggattccc tccatgatat ccctcaaagg tctctttcca cggattttaa cctgcccatt
    15661 tgctccggga aaacggttcc ggtaaaaaga taaaggtatc ccattaccct tatcgtgggc
    15721 aagggggatg tacttacacg atgccgggga cggaaaaccg ttcattgaag atcgaaaaca
    15781 tcgttgcttc agggtccatt gctgattcca tcgatctcgc agagatctcc tcccggatag
    15841 agaactgcat gctgaacagg aaaaggttcc ccggtgcagt attccggctt gaaaaaccaa
    15901 aggcggtctg ccttgttttt tcatcgggca agatcgtcct gacggggctc cgggaaaagg
    15961 aagcattgga cgaggcaatt tcccggatcg tcagtgcaat gaaggatgcg ggtgtcaggg
    16021 ttcactcccg cccgctcgtg accatcacca acatagtctg ctcctacgat gccggaaaga
    16081 tcatcaacct caacaagctc gtcgtcaccc tgaacatgga aaacatagag tatgaaccgg
    16141 agcagttccc ggggcttgtc tatcgcctga aagaccccag gatcgtcgcg ctgctctttt
    16201 cttccggaaa aataatcctt accgggggga agaacctcga tgaaatccgg cggggtgctg
    16261 acctcctcga acagaccatc gggatggtct cctgatctca ccagaacttc cgcgtccgga
    16321 tgtaattgcg ctccgcccgg ataatctctg tgtagaatgc atttccctcg gtcagggtcg
    16381 agaggatccg ggcagcgttc tcggggccga caccccgtgc ggcaagggca gttactgcct
    16441 tcctgccgct cgacaggacg aggtttgcat ttctcaggag cttcatctcg atggcacgat
    16501 cctcttcggt cttctgtttc ttcgatacct gcgcgatgag gggttcttcc cagggcttga
    16561 gaaccgctat caggcgtgcc tggcatcggg gacaccgggg agggtcgggc acgcggctga
    16621 ccaccgtccg gctcttccac ttcctgcagt tcatgcagaa aaggatgatc tcctgctggt
    16681 caatgcggcg ccgaagtgtt gcgatgaccg cctggtcagc agccggggga gggatcatgt
    16741 cacgggatga aaagagacct gcggctccaa tcaggctctg gtgcgagatc gcgaccctga
    16801 tgcttccctc ccgcacgagg gagacgatcc gggccgctgc cggaacgtcc atatagaccg
    16861 agaagagttc acggtacgct tctttctgga cgaccgtccc ctcgaatgtc tcgatgagac
    16921 gggataccga gatcttctcg tagtctgcat ccgggtcaat cgccccgaac ttctttgcca
    16981 cctggaccat tttccacttg aaaagtgctg tccgcttcat cgcaagctgg aggatcccct
    17041 ccaagtgcgc agggtcgagg gaaagcagcg tctccttcac gtcagctgcc tttaccgcgg
    17101 ggggaaggcg aaggaaaatg cggtaggcat cgatctcgat cccgactgtt gtcccgaaac
    17161 gggctgaaag caggatggag aggacgcggg caagggcctc gttggccatg tggcccgcac
    17221 agacattgca tacaacaccg tccggaacgt tctcgaggga aatcagggta tcatccggga
    17281 cgggggtccg gttcctgtcc atctcctcga ggaatctcgc tgcaaaggaa gccggatcct
    17341 ttcccgctgc ataggacgaa aagtcccttg tccgccggag catggcgacc tcgcgggcaa
    17401 tcgagaaggg gaccggtatc tgctctccct cccaggacgg gatctctccc tttaccttcc
    17461 gcgccggttc cacggtgatc ctcccttcgt cgatgtcaag gaccctccag agctgtccct
    17521 tcgtgacgaa gaccacgccc gtatggatga aaccggcaac gaatgactca tcgagcgtgc
    17581 cgacggtctt gcgcgatacc atgtcaaaga ctgtcacctt gcgctcgtct gggatcatcg
    17641 agaggttgcc ggagaggtat ctgcgtgaac gggccgatga ccgtacccgg tcgccgtcga
    17701 tcctgatcag gtggtgctct gccatctggg cacatacctc gtcgacaagg tctcctgcat
    17761 cgggaaacgg gtaactcctg cccacgatct cttttacctt cggcagcggg atctcccggt
    17821 actcgactgc aagggcagcg atctggttgg cgaggacatc tgctgcgttt attggaatgg
    17881 tgacctcttc gatctgtcct gcatgcgccc gtcgtgcaat cacgagtgac tcgaggagat
    17941 cgtcaaaccc ggtggaaagg actgttcccc tcgacacaac gtccagctgg tgcccggccc
    18001 tcccgaccct ctgcaccagc ctcatcacct cgcggggaga gccgaactgg atcacgtgtt
    18061 ctatccgccc gatatcgatt ccaagttcca tcgatgaggt tgcgatgagg cagcggacgt
    18121 cccccttcct gaacctttcc tcggcctcga tcctcacctc ccgcgagagc gacccatggt
    18181 gcacctcgac gtctcccctc gggtacaggc ggtgaccgag tgcctcggcg gttacccggg
    18241 tgttcacgaa gatgagggtg gacgaatgcc tgtcgattgc ccccgatatc cagtcgcact
    18301 gcgaatcgaa tgaatctccg gcaaattcca cccggatgtc gagactctct gcaacaggga
    18361 cggagactac cgaaaattcc ctcctcccgc agaggaactg cccgatatca cggggatttc
    18421 ccaccgtcgc cgaaagacct atcctctgga attctcccgc gtactcccgc acacgctcga
    18481 gtgcaacggc aagctgtgcc cccctcttgc tccccgccag ctcgtggatc tcgtcaacga
    18541 caacataccg aacgcccgcg aggtgcttcc tcatcaccct gcccatcagg agagcctgga
    18601 gggtctcggg agtcgtgatg aggaggtcgg gcggggagag tgcctgtttc ctccgttcgg
    18661 tctgggttgt gtccccgtgc cggactccga cggaaaagcc gaggttgctg caccaccacg
    18721 agagccggga gagcatatcc ctgttcaggg cccggagcgg cgtgatgtac agcgtcgtga
    18781 taccctgtcc ctttccggta agcatcgcgt caaagaccgg tatcatggca ctctctgtct
    18841 ttcccgtgcc cgtcggcgcg atgaggatga ggttctttcc ttccctcacg agagggatgg
    18901 ctgcttgctg gattggagac aggcgggtaa aaccccggtc cctgaccagc tggctcaccc
    18961 tcggatcaag gttcggaatc attggcatcc tcctccagga gagagagggg acccagaaaa
    19021 gtcccgtcgg agaggaatag ttcggatgtc gggatgtcga tgcagcggga aagggggctg
    19081 atggggtccc gtatcatgtg ctggatatcg taccctgcga gttcgcagaa ggcaggcaca
    19141 aagagtgccc gggtcaccgt cccggactca tcgccaccgg gggggaactg aaggcaggtc
    19201 tcgttcaccc tggcaagcag gtatcctgct gccctgaggg cacagccaac ctcgtccctg
    19261 accgagacca tgacgtggtg gtgccctgcc aggatcaggt gtccccggag ggccgggtta
    19321 gggtacgtgt gaccgtggag gtaccccact ccatcgacga gtgcgccgtc gcgggggaac
    19381 agttcatcgg gccggaggaa ctcctcgata cccgggtcgt ggtttcccgg gaggacgaag
    19441 aacggaatga tcgaccggat ttcgtcgaaa aaatccctta tttcccgcat ctcctgccgg
    19501 gtcgtgaagg gcacgccgtg cttgatgtcc ccgaggaggg cgagcgtgtc cggccctgcc
    19561 gactcgatgc aggcaatgag ccgatcgatt ctctccctgc tcctgctcct gatatggaca
    19621 ccctggcggg agagggacgg ctcgattccc aggtgaagat cgcctgccac gaggactctt
    19681 tcccggttct ccacaacgag ggccgggcca tccggtaaaa attccatttt cataagagct
    19741 tgaaggttcc ccggctcggc tggtaacact cgtcttccct gcagagaact tcgacagcgc
    19801 tcaggacgtc ctgatgggta agaccatggt tcgcggctct ccggacaatc tcctcgaggg
    19861 ttatcccctc cttccccccg tgttctttca ttatcgcgag gacgaccgat tcgggactga
    19921 gttccgattt tgccggagga ctttgggatt gcacgctctg caccgcatcc ctcacggttc
    19981 cggcaaggga acacagacgg gcgggattaa gactgtacga ggtcacgagc gccctgacga
    20041 gaggatcctc actgccagac cggagtgctg caccgatcct ttcgagacgg tccagggttg
    20101 cttccgccgt ccggagcacc catgtatccc ttgtataacg gtctgctgcc ctgatgtcga
    20161 gaaccctgag gatgcacggg gcaggtcgtc ctgtcccggc gaggaatggt tttccgacca
    20221 cggtggcaaa gcacggtgtc tcgagggaac agagggtggc ccttgcatcc ggtgactggg
    20281 gatctgcctg gagggagaat gccccggtcg ggtcagccat ccgggcacga accgtttcgt
    20341 tcccgcaccc ctgccgttca aggagggccc cgctggcaaa gaccagggtg aggagtgcac
    20401 ctcccggtgt gagcactgca ggttcggcca taccttcgcg tgaaaactgc accgtcgcag
    20461 cattgaactc cgctgcaaaa accctctgga acatcatgcc ctgctgatcc gatggttacc
    20521 ctgccataaa gtgcggcctg gtaccccaat gttagactgc tgtgcacata tccatattca
    20581 tgcaagaagg ggagtgccgg ttcccgtgat gggatatgtc aggatgctgg tacgtggcat
    20641 cgaaaacggg gaaaatgagg attgaatgag ggggtgcggg atgcgcgaag atggaaaccc
    20701 ttcgggaaac atgcgacttt ttacagtgac gaatcgaaaa acagagtccg gattgtccat
    20761 ttttgccaat agttttatat agggtgactt actccagtca ctgtacaggg tttatatgag
    20821 gtcgaaaggg ctcgcatgct tcgttatact cagccttgtc cttgtcagcg tgatctccgc
    20881 ttcccaggta cccttcccgg ttgacccctc cggagaatcc acgctgatgc cggtccggca
    20941 ggtggacccg gcacaaggtc aggaccaggg aagagtgcag gggggtacac aggctattcc
    21001 cctgcaattt gtgaaaaatg ccggacagag cgacgatggc gtggaataca tcgtcctcac
    21061 ggacggcggg tctctcttct ttgcccccgg cggtgtgtcg ataaagctcg tcacgcctga
    21121 cggacagaca ttccggacga ccagtcttgg ttattcattt tatggagcag atcctgatcc
    21181 tgaaatgaca ggactattcc cgcgtgaaag cacggtgaac ttcctgctcg gaaaagatcc
    21241 ctcgtcgtgg tacacggatg ttcccactta cggagcgatc ctttaccgcg acctgtatcc
    21301 cggtattgac ctggaatatt gtggaacatc ggacgggata aagagcgtct ttacggtagc
    21361 ccccggtgcg tctccggatt ctatcatcat tgaatacagg ggcgtgtcag gtctctccct
    21421 gacagacgag ggggcactcc gtatccagac cccggcagga gacctgctcg aatatccccc
    21481 ggttgcatac caggtcattg acgggcaagt cgttccaagg gacgtttcgt ttgccctgca
    21541 cggcaacaac cgggttggtt tctcgacagg gtcctatgac ccggagttcc cgctcatcat
    21601 tgatcctgtc atgaaatacg gggtctacct gaggggtgtc ggccttgcat acggccgctc
    21661 tgttgcggtg tccccggacg gaagcgcatt tgtcaccggt gagacgttcc ctgctcccta
    21721 ttcgttgcag ggagaatcga tcgggcccct tggaggtggc atggatgtta tcgtcgtaaa
    21781 agtcaatccc gaagggacag tccccctcta tgtcacctac atcggcggga gtggaaacga
    21841 gaccggatac gggatcaagg ttgatgcttc gggatatgcc tatgtcacgg gtgtcacgga
    21901 ttcacaggac ttccccgtga aggatgcact ccagggttac ctggccggag atacagatgc
    21961 ttttgccctg aaactctcac ctgacggatc aaatcctgtc ttttccacgt accttggtgg
    22021 gacaaggccg gattcaggga atgaccttgc cctcgaccgg ttcggaaaca tcctgattgc
    22081 cggtgacaca tcgtcgttct cgatgcccga tatcgaccat tccactcaca cagtgtacgg
    22141 cggaaaccag gatgcctttg tcctcaagct gacgggtgat ggaaaagaga tcgtatactc
    22201 tgaatttatc ggtggaaacc agaaggatgc cggcaatggc gtcgcagttg accgggacgg
    22261 caatgcatac gtcacagggg agacctcctc aaaagacttc ccggtcaaaa atgcttacca
    22321 gtcttcactg agcgggggaa cgtggagcga tgcattcatt acgaaggtga gccccggcgg
    22381 agagaccttc gtgtactcga cctatctcgg gggaccgcag attgacgtgg gtcatgccat
    22441 tgctgtggat tcgtacgggc atgcccacgt cacgggttcg acactgatga gcgtgtttcc
    22501 cgtgaaaaac gcgttccagc cggtttcggg cggcgcaatg gatgcgttct acagttatct
    22561 ctcggccgac ggcagggagc tcctctattc cacctacctg ggcggctcct gcaatgactg
    22621 gggtaccggc atcacgacag atgtctacaa cacgatcttc attaccgggt caaccgcctc
    22681 tctcgatttc ccgctcgtgg atcccttcca gccgcggttt ggcaatggtg accccaaggc
    22741 taccgatgcc ttcgtggcaa aattctgccc gtttgaaacc cgacccgatt atctcacata
    22801 ccttggaggt acgggatccg ataatggtgc atccgttgcg actgacgggg tggatggagc
    22861 ctatattaca ggtttcaccg actctcccaa cttcccgtca tcagacccct atcccccggc
    22921 attcgaaccg aagggacagg ggggattcct cttcgtgtta agggacgatg cctgcacgcc
    22981 accatgtgaa ctacccgttg ccggtttcgc ggcaaacccg gccagcgggc atgtacctct
    23041 cacggtcaac ttcaccgata cctcgactgg taacccggtc atctggtcgt gggactttgg
    23101 tgacggggaa acgtccccgg atcagaaccc tgttcatacc tatactgccg aagggaccta
    23161 taccgtcacc ctcaccgtta ccaacgagtg cggaccgaat tcaaccacca aacaggagta
    23221 catccatgtc ctcccgccct gtgtcccccc tgtcgccaac ttctccgcca annnnnnnnn
    23281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    23341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngtcctcccg ccctgtgtcc cccctgtcgc
    23401 caacttctcc gccaacccga ccgagggtta cgctcccctc gacgtcactt tcaccgatga
    23461 atcgaccggt gtccccacat cctggcaatg gtccttcggt gacggtgcca cctccaccga
    23521 caggaacccc ttccatacct acaacctgtc cgggacctac accgtcaccc tcaccgtgac
    23581 aaacgactgc gggtccaact cgaccaccag acaggagtac atccacgtcc tcccgccctg
    23641 cgaaatgccg gtagccgact tcctggcaca cccgacatgg ggattcgtac cgctctgcgt
    23701 ctcgttcttt gatacatcca ccggcaaccc gtcatcctgg tactgggaat tcggtgacgg
    23761 tgccacctcc agcgaaaaga accccgttca cctctactcg cagacgggga cttacaatgt
    23821 caccctcacc gtgacaaacg actgcgggtc caactcgacc accaaacagg agtatatcac
    23881 cgtcgtccca ccctgcgatc tgcctgttgc caatttctac gggaacccga ggacggggac
    23941 caatccgctc ctcgtcgagt tctgcgacct ctcgacgggc gggatcatca gctggcactg
    24001 ggacttcggt gacggtgcca cttccgagga acagaacccc atccacatct acgagcaggc
    24061 cggcaactac actgttacac tcaccgtgac aaacgactgc gggcctgaca cggagacaaa
    24121 gacaagttat atcacggtct cacaatctcc gtccggtccg ccggtcgcat attttgcggc
    24181 gaatacgaca ctgggaatcg tcccgctccc cgtggcattc tatgacctct cgtatgggaa
    24241 ccctgcaaca tggcagtggg acttcggtga cggtgggacc tcctctgaac ggaacccggt
    24301 acatgtgtac cgttctgccg gaaccttttc cgtctccctc accgtggcaa accccaacgg
    24361 aaccagcacg ttcacccgtc ccgagtatat taccgtgctg agcccgatcg gaggtgatac
    24421 cggctacttc cgcgtccatt gcaacgttga cggggccaca gttcacttca accaggacta
    24481 caagggacag atccaggacg ggatccttct cgtcatggta tacctgacag gatctcccta
    24541 taccagttac accgtggcca aagagggcta ttacccggtg acccagccga tcacagccta
    24601 cccggcaaag gaccagaccg ttgacctcta tgcggtcctc gaaccaatcc cgaccatcaa
    24661 ctacacggtc accgcgaccg cagggccaaa cggtacgatc aatcccagcg ggaccatgac
    24721 ggctcccgcc ggatcgagca tcgactttac catcgttccc gatacggggt ataatccccg
    24781 gagcctttcc ctcgacggag tagaccttgg tgcgctccgc agttaccgcc tgtcggacat
    24841 ccaggcaaac cataccctcc atgcggagtt cgagaaggcc atctttggta tcactgctct
    24901 tccgtccgag aacgggacga tcgtcccctc cgggctgacc ctcgtgccct acatggagag
    24961 ccgcgacttc cagattgtcc ccgactccgg tttctacacc gcaggcctgt acattgatgg
    25021 cgtcggcgtt gcacctgtcc cggtctacac gttctccaat gtcgtgtcca accacacgat
    25081 atccgcagta ttcctgcccg aaggatcact cacgttctat attgatgcag ttgccggtga
    25141 gggtggcacc atctctccct cgggtctcgt cagtgtcgcg ggcggaagca acatcacttt
    25201 caccatgaca cccctgaccg gttactacac gaagaacgtg atggttgacg gggacagcaa
    25261 gggtgcccat gaaacatgga cgtttaccaa tgtcgtgtcc aaccacacga tcagcgtcac
    25321 cttcgagaag tcaggcggtg gcggtggcgg cggtggtgga ggcggtggcg gtggcggcgg
    25381 tggccccttc gtcaccccga ccccgaccgc agtgcccacc tcccaggcca ccgagacgga
    25441 aggctacgag agcgggggta ccgtgacaat cgccaatgcg acgccgaccc tgaccaccgt
    25501 tccgacagaa accccggcag aagaagagac cacaaccgtg gcgacaacga ccatcccgcc
    25561 ggctaccccc tactggaccg ggttctccct ctactggctg ctgctcctgc tgatcgtcat
    25621 cgcagtcctt gccgcagtgg ggtattacta ctggaagaag gaacaggcaa aagtggccct
    25681 ctttgaagag gagggcaggt aaattcattt tccttctctt ttaatttttt taaattacct
    25741 gttttgggta attcccggaa tatccatccg ggcctccgat ccccaaaaca cgatcaaccc
    25801 cttcctccgg ttccatgggg ggacacatct gccaaacaat aacacctttc tcctcctgcc
    25861 gcagatatac tggagatata ccccgcggca ggaaaaaccg gaggtacatg atggaagaga
    25921 acaacctgat ctggatcgag aagtatcgcc cggtcaggct ggcggacatc gtcggccagg
    25981 accagattgt cgagcggctc agctcgtacg tccggacagg gaacctgccg cacctccttt
    26041 ttaccgggag tgcaggggtg ggaaagacca ctgctgccgt tgccctggca cgggagttct
    26101 tcaaagactc atggcacatg aacttccggg aactcaatgc ctctgacgag agggggatcg
    26161 atgtcgtcag gaaccagata aaacagttcg cccggacatc gcctctcggc ggggcaggtt
    26221 tcaagatcct ctttctcgac gaggcggatg ctctcactcc cgatgcacag gcagccctcc
    26281 gcaggacgat ggagagctat gcatccacct gcaggttcat cctctcgtgc aattattcct
    26341 cccgcatcat cgacccgatc cagagcaggt gtgccatcta caggttcagg agtctctctc
    26401 cggaagccat cacgaaggag atcctgagaa tagccgaaaa cgagaaactg actattaccg
    26461 gggaggcgat tgatgccatc atagagatag cgcagggtga tatgcgaaaa gccatcaatg
    26521 ccctccaggg tgctgcaatc ctgtcaccgg agatcaccgg ggacatggtc tacgccatca
    26581 ctgccacggc ccgccccgac gagatagagg atctcctctc gacttctctt tccggcgact
    26641 tcgaaggggc aacggcgatt ctccaccgcc tcctcaacga cagggggatt gcgcccaacg
    26701 agctgataaa ccagtgttac cgggccctca ccaggcgtga catggaggag gatatgaggg
    26761 ttgcactcat cgaccagctg ggcacgaccg atttccggct atccgagggc gcaagcagcg
    26821 acatccagat ggaggccatg atcgcccggt tcgttctcct ggcacgcaag aaatgaagag
    26881 aaaagaaccc gcccccgata ccgaggcaga cgcggaggtc atcgaccgcg acgcggactg
    26941 gagccggttc ctcaagagca ggtacaggaa acagctctcg gaactcgccc gcgagtatcc
    27001 ctacaggcgt tccatcgaga tcgattaccg ggaactcgag agctacggca agaccggtct
    27061 ccgcatggcc gatgaactcc tcgagaaccc gggcaaggtc atcgaggacg tcaggaacgc
    27121 gatcaggaac caccagctca tcaaggggaa ggacggaaaa cccaccgggg atgtcaatgt
    27181 ccggttcatc aacctccccc ggaagatcgg tatccggcat atacgctccg atcatatcaa
    27241 caagttcatc agcgtcgagg gaatcctgcg caagacaacc gaggtccgcc cccgcatcgt
    27301 ccaggcagtc ttccggtgcc ctgccggcca catcacgatc aaggagcagg ggtacgggcg
    27361 gttccgtgaa cccgacgggt gcgcaacgga agggtgcacg ttcaagaaac tcgaactgat
    27421 gcccaggcgt tcccggttca tcgactccca gaagatacgg atccaggaat cccccgaagg
    27481 gctcaggggg ggagaacaac cccagacgct ggacgtggac gtcacggacg acctgaccgg
    27541 gaaggtcgcc ccgggggacc gtgtcgtgat caacgggatc ctgcgctcgg tccagcgtgt
    27601 cacccacggg gagaagaaca ccgtctttga catctacctg gagtgcaact cgatcgagat
    27661 agccgaaaag gagttcgagg aggtacagat agacgaaaag gacgaggaga ctatccttgc
    27721 cctctcccgc gacccccaga tctaccgcaa gatcgtccac tccatcgcac ccaccattta
    27781 cgggaacgag gacgtgaagg aggcgatcgc gctccagctc ttcgggggta tcgcaaagga
    27841 aatgcccgac gggagccatc tccgcgggga tatccacgtc ctcctcatcg gggaccccgg
    27901 tattgccaag agccagctgc tgcggtacgt cgtcaagctg tccccacgcg ccatctacac
    27961 gagcggccag tcatcgacgt ctgcagggct cacggcaacg gcagtcaagg acgagttcgg
    28021 ggacgggcgg tggacgctcg aggcaggagc actcgtcctt gccgacatgg gtatcgcagc
    28081 cgtcgacgag atggacaaga tgcagaaaga ggaccgctcc gccctgcacg aggcaatgga
    28141 acagcagtca atcagcgtcg cgaaggccgg gatcacggcg accctcaagt cacggtgcgc
    28201 acttctcggt gctgccaacc caaaactcgg caggttcgac gactatctcc cgatccacga
    28261 ccagatcaac atgcccgggt ctctcctctc gcgttttgac ctcattttca agatgagtga
    28321 caagcccgac cacacccggg acagcgcgat cgcatcccac atcctgaagg cacacagcat
    28381 cggcgagacg atcgcccagc accggcactc ccccattccc ggcgtggacg acaagtacat
    28441 cgaggaacag ctcaagcccg tgacccccga gatcgatccc ggtctcttcc ggaagtacgt
    28501 tgcctatgcc cgccggacct gcttcccccg cctgacggag gaggcaaggg aagcgctttc
    28561 tgcgtattac atgcagttgc gggaccttgc ggcaggatcg gacaagccgg ttcccatcac
    28621 ggcacgccag ctcgaggccc ttgtccgcct cgccgaggcc agcgcccgga tacgcctctc
    28681 gcaggagatc gggagggagg acgcagaacg ggtcatcaag atcgttgatg cctgcctccg
    28741 cgaggtcgcc tacgatccaa agacggggac gttcgagatc gaccgcgtct ccagcggtat
    28801 cacgaaaggc aggcgtgacc tgatcaggac gatcaagcag acgatccggc agatccagaa
    28861 ggacacgggc aacgaccggg tcgccgtggc agagctgatg gatatcctcg ttccccaggg
    28921 cttctcgcgc gaggagataa aagcccagat cgagctcttc ctgcgggaag gcgaggcaat
    28981 ggaacccaaa tccgggttca tcaagctcat ctgaagtatc cacccctttt ttgctccccg
    29041 gcgccaaccg gtaccgcatg ataagtgcgc gagaaaaggc catattcgag gcagggataa
    29101 agcttggcgc cctctatcac cagtgggtcg gatcgccggt cagcccgcag acggcagcca
    29161 ccctcgagcg ggcaatcgag gccagtgtat cgctccagcc gttcgtggaa agggttaccg
    29221 tgcagctcga caggagcctc atggcgccaa acacattcgg gtactcggaa ctttccggcc
    29281 tgatgttcga tgtcgagatc gtgacccgtg tcgacggtgt ggcgtgccgg gcgaaattgc
    29341 gccgggacgg gacctatccc ctcatggaga tcgtggagta aatgtccagg ccgtcgtctc
    29401 ccgtcacgga cgaccatatc cacatcgacc cccggaacgg cagggggctt gcagcagccc
    29461 gtgacttctt ccggtcaggc gggacccaca tcttccttgt cagcaaaccc tcctcatcgt
    29521 tcggtattct tcccctgtgc ggtgaagact tccgccccgt ctttgaagag acgctctcgg
    29581 ttgcggaaat ggtttccggc acgggtgtcg tcgtcttccc cgtcctcggg gtgcacccgg
    29641 cagagatcac gcggctgctg gaacatgttc ccctcgaaag ggcagctggc atcatgaagg
    29701 aggggatcga tctcgcggcc cgtttcgtgg aagaaggccg ggctgtggcc atcaagagcg
    29761 gcaggccgca ctacgaggtc ccggcagatg tctggaccgc gtcctgcgag gtgctctcct
    29821 atgcattcga acgtgcgggc gaggccgggt gtgccgtcca ggtccatgcc gagagcggag
    29881 actgtgccga catgcgggag atggcatcct ctgccggcct cgatcccggc agggttgtca
    29941 agcactatgc agtcccctcg accccccttg tcccttccct gatcgcaacg aatcccgcag
    30001 tcccggatct ctgcaggcag ggacgggcat tcatgatgga gagcgattac atggacgaga
    30061 atacccggcc cggtgcagtg atcgggccgc gttccgttcc gcgcgtgacc cggaaactcc
    30121 tcgaagccgg agagattgac gaggacagcg cgtaccgtgt ccatgccgag accccctcgc
    30181 gggtctacgg cgtcgagata agcctctgaa atacccgctg ttgcagtatt aatactcctt
    30241 ccgaccaacg ttattcaaat gtacatgaag gttcaccgga ccccgaaagg ggaagaggtg
    30301 gttgcagtgt gtgaccggga actcatgaat accacccttt accgggaagg agtcgagatt
    30361 cacatccgtg gagagttcta cggggaccat accgtgagtg ccgacgaggt cagaaaggcc
    30421 cttgtcaatg ccgacaacgc aaacctgatg ggcgagagaa cggtcgctct tgcactcgag
    30481 atggggctca tcagccggtc ttcatgcctc atgctcgggg atgtccccca cgcccagata
    30541 ttccggatct agaagagatg tccatccagg attcaatatg ccccctctgc gggaaaccat
    30601 cgccacgggg cgaggtctgc gggccgtgcc gggtcgcaaa gatccagtgg ctggagtgcc
    30661 cgtcccgcgt gcaggtcgtc gtgtgcccca cgtgcggcgc ccgccgcgag gcaggtacat
    30721 ggtcggacat gccctgggaa gctgccgacc tggtcgggtc gctcgtccgg aggtcgctcg
    30781 tcttccaccc tgaattaagg gacgtggacg tcgatctcgc cgtgcgggaa aggagtgtca
    30841 accggagcac cgtggaatgc accatccggg gaagactctt ctctgtccct gtcgagggat
    30901 cctgcaccgt cgaggtggaa tggaagaagg aacaatgtga ccggtgttcc ctcatcagcg
    30961 gcagttacta cgaggggatc gtccaggtgc ggggtacggg caggagacca tccccccggg
    31021 agatcgagga gtcacgccgc atcgcggatg caatccttgg atccctgaat gctgccggcg
    31081 agaggcttgc cttcatctcg aagtgggacg aacaccgcga cggtcttgac atcacagtcg
    31141 gatcgcagcg ccttggccgg gagattgcgt cgggaatcac gcagacgctg gggggcagtg
    31201 tttccacgca ccccaagctc gttggcgaga aggcaggaaa gcagatattc cgcgtcacct
    31261 actcggtccg cctcccccgg tactcccgcg gggatatcct cgtcgtgcgg gggaagtatg
    31321 tcgaggtcat cggggtcgag gggcgcctct tccgctgcat cgacatcgaa tcagggacca
    31381 caagactctt tagggagggg cagatcgaga gaagagccgg acggagagag gattccaccc
    31441 tctggcaggt catcttccgg gaccgcgacc tgctcgggct catggacccc tcgaccggca
    31501 tcacccgcga ggtccttgtg cccgcaaagg gtgtttttcc ccccggctcg ggtgtgcacg
    31561 tctttttcga cggggagaga ccggtcatcc tcccgtgata accatgatga gggttcgcga
    31621 ggtagcacga ggggacctgt cccgtatcag ggacgaagac tgggtggact ggtcccgccg
    31681 gcccttcgtc cggggggatg tcgcgtatgt cccggtcagg gacgggttct ctttctcgtc
    31741 gatcctcccc gatccccaaa cctgccgggg aaggggatat accatgatag ggacggtagc
    31801 cgtgttccac gggaaagaga agccccggga tgctgatgtc agggcagtcg aagtgtccag
    31861 gaaaccgacg gctgtcctct ggattccctc gtccgagggg cagaggagaa aaccccgtgc
    31921 ccacgtcctg gccgggacgc ccggggaagt ggcacacagg gaatgcggca taacctactt
    31981 cctcgacccg tcccgcatca tgttctccgc agggaacagg ggtgagaaag agaggctccg
    32041 caagatggtc cgccccggcg agagggtcgc ggacatgttt gccgggatcg gctacttttc
    32101 gctccccgtt gccgtgcagg gtgcaaaggt ccatgccatg gagatcgatc ccgatgcctt
    32161 ctcgttcctt gtcaggaaca tcggggcaaa cggggttgca gacctcgtcg tcccgcagct
    32221 cggggactgc cgatcctgcc tctccgggac atacgacagg atcatcatgg ggcactttga
    32281 ctcctgcctt tacctggact gcgctctctc ccacgtgcgt gaaggctccg ttctccatgt
    32341 ccataccgcc ggggacgcgt ccggtcccat cggggatttc ctggcaggca gggggatccg
    32401 tgccacggtg gagacccgca gggtaaaaaa actgggcccg cgtatatggc actgcgtgca
    32461 ggacgtgacg ataggatgat gcactattct cccctggcgg gaaaagaggt cgtgctcggc
    32521 gtgtgcggca gtatcgcggc ggtagagact gtccggctcg cgcgtgccct gcagcgcagg
    32581 ggtgcgtgcg tccaggcggt gatgagccgg gcagcctgcg atatcatcag tccccatgca
    32641 ctcacgtatg cgaccgggag acccacaatc acggccatct cgggcatggt cgaacacgtg
    32701 cgccactgtg gcgacggcgg atccgcagat ctcctgttga tcgcccctgc gactgccaac
    32761 actctctgca agattgctgc ggggatcgat gacacgccgg tcaccacgtt cgcgaccacg
    32821 gcaatcggga ggggtatgcc tgtcgtcgtt gcaccggcaa tgcacgaatc gatgtaccgc
    32881 caccccggtg tcaggcggtg tctcgaaacc ctcggggaat ggggcgttgt cgttgccggg
    32941 ccacggatcg aggaagagcg ggcaaaaatt gccgacatgg aggagatcat cctgctgtgc
    33001 gagcgcgagc tctcgggaaa accgctctcc ggccgccacg tgctcgtcac gagcggggcc
    33061 tgccaggaaa gggtcgatga cgtgcgcatc ctgacgacac ggtcctcggg caggatgggg
    33121 caggcactcg ccctccaggc attccggctc ggggcgcggg tgaccgtcgt gcacagcgcc
    33181 agcctccccc tcgttgaaaa tatccgggta tcggacgctg caggaatggg ggaggcagtc
    33241 cgcaggatct gcagcacaga tcccccggac ctcttcatat cggcagccgc ggtctccgat
    33301 tttgcgccgg aacccttccc cggaaagata ccgagcggca gggcggtgac aatcgacctt
    33361 cacccgcttc ccaagatcat tgacgaggtc gcgggacact tcggtattcc cacggttgcc
    33421 ttcaagctgg ggcgaaacgc cgttgcgcag gggaatgcca tgctgaaggg aaacataggg
    33481 atcgtcgttg ccaacgaacc ggacgccatc gggcaggata ccgcttccgt gacgatcctg
    33541 tcccggaacg gtcctccccg gcatgtcgaa gggaaaaagg aagacatcgc cgcagagatc
    33601 ctctcggtgg ccatcgggac tttttccctc tcccgggtaa cctgaccgga taaatttgcc
    33661 cggcaggtca gatacttatc ctccggttgc ataatgagag gtacattcct gctcaaagcc
    33721 aggagatctg atgttccatg acaccgtgcg cttctgccac cagtcccggt cacctctccg
    33781 ggtatttccg gcctgtctat ggacccacac cggcagacac cgggagcctc ggtgccggaa
    33841 tcgtaatcag cgaaggcgtg acagtcacaa tccggccggc tgaagagacg aatgtcattg
    33901 tcgagaggcg ggatccccgt gacgggagga ttgtcgaggt gaccgggtcc tcacccccgg
    33961 tggaatacct cctctcgcgg ctcggtgtca gggcacgggt aaggacggtc tgtttcctcc
    34021 ccatcggggc tggttttggc ctttctgccg ctgccctcct tgcgaccgcg gtcgcagcag
    34081 acgccctctt tgacctctcc ctttctcccc cggaacgtgc cagtcttgcc cacgaggcag
    34141 agcttgcgtt tcatacgggt cttggtgacg ttgcagcatg cgcgggtggg ggccgggact
    34201 gcaggaaagg tccggggatc gctgcttcca tcgagcgatc cttcgatgtt gtcgaaccgc
    34261 tctgtgccct cgtcttcggg ccgcttccct ctcccgggat tctccagtca cgggaagcca
    34321 tggaaagggt cactgcagcc tttccggatc ggtgtccggg agacgtggat gactttttcc
    34381 ggctttcccg cgggtttgcc gagaaaagcg ggctgatgac acccgaggtc cggcaggctc
    34441 tggctgtatg tgacggcgcg ggtatcgatg caacgatgac aatgcttgga aacggcatct
    34501 ttgcatacgg aaaggaagcc cccggtctgc tcgcatccat gggcgaggtg ttcctgctgc
    34561 acccggccga caacggtcca cgcctcgtgg aggtgagacg gtgattcctc cggatcaccc
    34621 gcggtaccgc tccctgctcg cgagggaacg gatcgcccgg tacgcggccg ggggaattgt
    34681 caccctcgag ggacttgcag cccacgggcg cggggaggca ttcgattacc tcatcgggga
    34741 acggacgacc gagagcgcac tcctggcaga aagaacggcg gccgcgctcc tcctgtgtgc
    34801 ggagcggccc gtgatctcgg tcaacggtaa tacggccgcg ctcgccgctg accaggttgc
    34861 acggctccag caggtgtccg gcgcccgcgt ggaggtgaac cttttccaca ggagcgagga
    34921 gcggatacag aagattacag cgctgctcga ggacgcgggg gttaccgtcg ggaaggggag
    34981 agccgagcgg ctccttcccc tctcgcatga ccgtgcattc tgcttgaggg acggtatcta
    35041 ctctgcagat acggttctcg tccccctcga ggacggtgac cggtgcagtg cgctgcgcac
    35101 catggggaag acggtgatcg tcatcgacct caacccgctc tcccggacag cacggacggc
    35161 aagcctcacg atcgtggacg agctgacgcg ggctttaccg cacataacag aggcatgtgg
    35221 tgtcctttcc cgggaggagg cactgtacct gtgcagctcg tacgacaaca gaaagtttct
    35281 ttccgacgca ctggcagaga tccagaggag gcttgcacgt gctctggatt gaaaaataca
    35341 ggcccgtatc atttgaggag attgtcgggc aggagagagt cgtcgggcgg atgtcccatt
    35401 ttgccgccgc ccgctccgta ccccacatga tcctggcagg accgcccggg acggggaaaa
    35461 gcgtgagcgt ggaatgcctg gcaaacgcac tctacggcga ttttgctccc gagaacctca
    35521 ccgtgatccc gacctctgac ctcttttccc agggcaggaa gttcctcgag cgcgaggaga
    35581 ggtatgcgca cctttaccgc ccggaggaga gcgtgctctc gaatttcaag aggattatcc
    35641 gggaatatgc aagcttaaaa ccgctggatg cagaattcaa actcctcgtc ttcgagggcg
    35701 catcgtccct cccccgggag gcgcagcagg cgttgcgccg gatcatggag cggtcctcgc
    35761 gcacgtgcag gttcgtttac tgcacctgcc acccctcggc aatcatccct gcaatcgcct
    35821 cgcgctgcct gcctctcttc ttctccccga tccctgacga tctcgttgca tcgcacctcc
    35881 gcatgatcat cgatcgcgaa aggggtcccg aaaacacggt gggaaacgat gacctcggcc
    35941 tcgtcgttgc tgcagcgcac ggggacctgc gcaaggcagt catgcttctc caggtactct
    36001 cggagaccgg cagggagagc ggttttcgtg ctctctcgga gagcgagaca ggacagcttg
    36061 ccctcgcagc cttttctgca atccggaacg gagacttccc tgcagcctgc aggagagtcg
    36121 aaaacctcat gatcgagtac gggctttcgg cccgggaagt gctccgtgaa ctctcatcgg
    36181 ccgcgaaacg tgacttcaat gacccccgta tcgcgactgt tctcggtgac ggggatgcaa
    36241 acctcatcca cgggcataac gagttcatcc agttaaacgc cgtggtcgta aaactcgcaa
    36301 cgatcgtcag ggagaaccag gggcccgcaa attcccctga catgcaagca tcttcttgat
    36361 ccgctccttc ttttccatgg ccgcagtggc cgcctccccg acagcccttt tcatctcctc
    36421 aaagtcacgg tgggttgaat cgacaaccac cttgacgggt gtataggcag attcgcggaa
    36481 acgggggacg aaatccacga tctttccccc ggtccggagg aacgccccgg gttttccttc
    36541 cacgacttct cccaccctct ccaccttcac ccctgccccg cggatgacac ctgcgacccg
    36601 gtctgctgca ccggggggca ctgtgatgag gagagagtca agcgagaccc ccaggaagtc
    36661 aatcgagagc tcttcgagga gtccgtaaac atcctcctgg acgagtcccc cgaccttctc
    36721 ctcgtcgatg acaaccctgc acctggctgt cgcggcaagt tcgtgggcgt caccgcggag
    36781 cccgccgttc gtcacgtccg tcatcgcatg gatctcccgg agtacgggac ttgcaaggag
    36841 cgcctcgcat gcctggagga agtggaggtt gatcgtgtgc ttcacgacat cggggaaacc
    36901 ggaatagagg gcagcagttg caatggtccc cccgcctgca ccctctgtca tcaggatgac
    36961 gtctcccgga cgtgcttcgc ggcgggccgt gaggtggccc gcgatcccga cagatcccac
    37021 gcagcccgtc atgcgggagc caaggaccat gtcgcccccg atgcggagtg tcgagcccga
    37081 gacaaggggg attcccatcg actcgccgac ggtgcagact cctgccgtgt aatcgaatat
    37141 cttcgcgacg tccccgttgt cggcaacgtg gatatcggag aagaggagga gcgggcgggc
    37201 gcccatgacg tagacgtccc ggagtgtcgc cctcgttgcg tgaaacccgg caaggaacgg
    37261 gaagtccgag aggcgggaat gcatcccgtc aacggtgcag accaggaacc gtggcacccg
    37321 gtctcccgca gaggggatgg caaccgcccc ggcgtcgtcc atctcgtcca ccccaaccga
    37381 cgcggatgtt ttcccgataa ttcttgctat ctggcggtgg gcaaaaaagt cccctgtacc
    37441 ccgggaaccg accccgaact ctcccatgga gactcctgac tcccggaatg agaagaggtc
    37501 tccggagagt ccggtcgtat tgcggacttc cgcgatgact gcccctgcaa acgcctcgat
    37561 gtaattgtcc ggcgcacccg gcttgtattc cctgatgcgc tgcacgagtt tctcccggac
    37621 ctccctttcc gtcgccccgg acgagagcgc acggcgggtg aactcctcca cgtccatgcc
    37681 tgtcatgtag aacgtcgagg gtcataagga aaagccctgg tgccttcaga tgggtaatcc
    37741 cggaatgatt aacgatccgc cggggtcgct ttcccttctc tgtcatttcg tcctgatgag
    37801 tggcacgaac ggattttttg cctcccggag tatcgggttg gcaaatcagg agatgaaagg
    37861 gtcacttgag ccaaaaccga atgctggaac cgcaggcggt ttttagtgaa aaaaaagcgg
    37921 tgaaaatata cctttccttg aaaaaatgag cgtatttaac ccggcacctg actcccttcc
    37981 cctgccttcc acgtgtggac gagcgggggt atctcgatcc tgtccgggaa cgtctccacg
    38041 taaccgtcag ggaaccggat tgtcgtcacg gaaggcgaga ggtcagctgt aaccagcggt
    38101 gcaaaccagt acgttttcag gatcttttca cccgcggcaa aggagagccc cggggtacgg
    38161 gccgtcatag tcccgttgct gctgctgacc tgtgcaaacg agtcgactga caggtgcacg
    38221 ctgttgctgt tgacagagat aacggtgacc ggttttccga agttcgattc cagtgctttc
    38281 ttcagctcgg ccgcaggatc caccagccgg aggtagactg cgatgtactc gagccagtca
    38341 aggtgatacg cgaaacgaat atctgccttc ccgtcctgcc ggatggatat gtccagtgac
    38401 tcggatgtca tggcatttgc cgggatcgcg accagcacca gcaggatcac gattgccacg
    38461 ggccatgcag aggtgtgcat atgtgagacc tcctttgtgt caggatggtg cagcgtgcgg
    38521 gataaatttt ctccccatgc tcttttgggc ttttttatgg cggacgtggc gatatcctct
    38581 ttaccgagca ctcctatacc cagagttatc catgcgaaag aaacacctgg ccgcctgcct
    38641 gcttgtggcc tgggtcctgc tggtcatcgg gttcatgatc cttgcccgga cactcgacct
    38701 cgagatcttt ttcgtcctct ggctgattgg aatcctcgtg gttgtcgagc tggcctctga
    38761 tcatttcgcc accccgcgcc atctccaggt acagaaattc gtgatcgctg caggcgtcgt
    38821 gctctttggt gcaatcgtgg cacgcaaggt cctggagata ctcgcccgat gatacgaagg
    38881 accattcttg ctgcaggagt cctgctgggc atcctctgcc ttgccatcgc cgggatgcat
    38941 gccttctcac cccttctcta cagccctgct tccgactccc gtgctccgga ccatgtcaac
    39001 cccctcgcgc tcaaacacgt cacatccggg aggagtgcgc ggatcatccc gctcgttgca
    39061 gacatcatag gaaccccggg ttcccttgtc ctgaatataa ggtcgaaaga tttcgcgagc
    39121 gcttcccgtg acctgcagga gtaccgcgat tctctccgga acctcgatac actcgtcatc
    39181 cagctggacc ttgacgaggg tgaaattgcc aagttcaggc gggcggggcg ggaaaatgcg
    39241 cagatccttg cagagctcct gaacggaacg gagaggtggg acgacctcaa aactctcgaa
    39301 gtgcggttca gggaatcggg cgataccgcg atggagacga gcgtcaggta cgaaggagag
    39361 acgttgaagc ggaaaatcca ggacctctac agggagtacc tcgaacagga cgatgtcatt
    39421 ctctcgacgg gagagaagtt cgagctcgat acctcgggac ataaaaagag tatcacggag
    39481 ttccgcgaga ttgtcaacag catcaccgcc ggcgatgagg agaaggaggg aaccctggcg
    39541 ggtcccggtg acctccctgt attcctcaat gtttcacccg accgggcctc ctacggggat
    39601 actgtccgga tggaaggaca ggtaaaagca gcagggagca acaacatcgg ggacatcgcc
    39661 ctctttgtcg attcagcaag gaacgtaacg cttcggaccg gaccggacgg gtctttttcc
    39721 cattcctacc gcgtggagag ggaccgtgcc ggcacccata ccgtctttgc cgtctacgaa
    39781 gggtcactct tctcccccat cgagtcgttt accgttgaag tcattccctc cttcctgcag
    39841 cttgggccac cccgtgtgca gagcggcaag gttctctgcc acggaaccct ttttgccgga
    39901 tcgcaacccg tgacgggagc acctgtcgaa atccgtgcag atggaaagcg ggttgccacg
    39961 gcgcagacga aggatgatgg tacattctcc gcgcaagtcc gccttgaacc gggtacctac
    40021 agtgtccggg cgcaattcga gggggaggga tttcctctcc tcccctcggg aagcgaatcc
    40081 tacgaagtac tcgtcccggt acctcctccg gccggcgttg acgggaaagg cttcttcacc
    40141 gaccccctct ccctcgtggt ggtgagcggc tttttatgcc tctcgggagc gggtgcgttc
    40201 tattacctcc gccgcaggag acacggcatt ctcccggccc gcacgccgct ccctgttccg
    40261 gagatgatgg acgcacctgc atccgtgccc gtcggggaac aggtctttcc ccctgccccc
    40321 ccggcagaaa caccgccaga gcccggtctc cctcttcaag cgggtgatgt gcgggatgtg
    40381 tcctggcagg agctcttcag gcggctccgg gtcgctgtct caaaggtcgc ctccctgcgt
    40441 tacccccagt ccctcacacc gcgggaggta tgcgcttcct gcagggatac acggatccgc
    40501 gagttcgtct gccgtttcac gagcgggtac gagagggtga tgtacgcagg gggggatctc
    40561 ccgcgcgagg agaaagaccg catgatggag gcttaccggg ccgtgctcgg catcctgggg
    40621 gggaaggacc attagcaggg cggctcttct tgcggcggga ttcatcgtgc tgggggtggt
    40681 cctcgtgctc ctgcacctct ctgccacgaa cgctgactac agccggtaca accccgggtg
    40741 gaacgggaca tccgttctct tcgacatgat cgacgaggcc gatgggacca tggtcacgga
    40801 cccttcgcac ctttccgggc agggcgatgc catgctcctc ttcgttgctc ccggccgaaa
    40861 accccctgac gaggtcaggg aagagctgag ggacttcctt tcccgtggaa actgcctcct
    40921 catcgcctct gacagggagg aggacaacgg gctgctcgag ggtataggca gttccatcag
    40981 gatacgccag tcagacatca tcagcgtgga caggttcttt gatgaccctt cctctgtcat
    41041 cgctttcccc gcgggggatg acccgctttc tgccgggatt ccccgcctcg tgggaaacga
    41101 cccttcgttc cttaccgggg gaacgcccgt ctttgcaaca tccctcctct ctttccggga
    41161 tacagacggt gaccagaggc ttggaaaggg agaggtgctc gagaggttca ctgtcgtttc
    41221 ccgggagacc atcggaaacg ggacactcta cgtggtttcc gacccaagca tcttcatcaa
    41281 cgggatgctt gtggcaaacc cgccgaccgg gaacagggag ttcgtggcac gaatcctctc
    41341 tctccgcccc gtgctcctcg ccgagcaggg ttattcccgc actgcggagg gcggaccagt
    41401 gatccgagtc attaatctgg tgaaggatgc aacatctatc gaaatggcag caatcaccct
    41461 ctccatgctc ctgttgggcc ttttccttgc gttcgggagg cgggacgcat gacggttccc
    41521 accgatgagc tcgcaatgct cgccgggtat taccgggaga taaaaaagag gatgggagag
    41581 ttcatcgtgg ggaacgagtc cctcgtggaa ctctgcatga ttgcgctgct ttccgggggc
    41641 cacctcctca tggagggcac gccggggacg ggaaagacat cgatcgtcaa gacgattgca
    41701 cggctcacgg ggtgcgcatt cgcacggttc cagtgtgccg tggacagcca gcctgcagac
    41761 atcctgggtg tgcggatata cgaccaggaa aaaagggatt ttaccctgcg aaaggggccg
    41821 atcttttcca acttcctcct catcgacgag atcaacaggc tcgcacccaa gacacagagc
    41881 gcttttatcg aggcgatgag cgagaggcag gcgacgatcg acgggattac catgccgatt
    41941 gcccccccct ttaccgttat tgccacccag aaccccttcg agttcgaggg gacgtttccc
    42001 ctcatcgagg cgcagaaaga caggttcatg ttttccatgg ttctctccca gctcgacggc
    42061 gatgctgaac tcgagatcat ccggcgggaa catgcgggga aactcgactg ggactcgttc
    42121 tactcgcagc tcaaacccgt gatgaacagc gagctcatcc tctccctcgt cagctcggtt
    42181 gcccgcgtgc atatcgacga acacctgctg gcctatatcc gcgacattgt ggtcgcaacg
    42241 cggaaccata gcgaagtgca catcggcgcg agctcgcggg catccatcgc actggtcagg
    42301 ggatgcaagg cccttgcggc tctcagggaa cggacgtacg ttattccgga tgatatcaag
    42361 taccttgcac tgccggtcct tcagcacagg attattctca cgcaggaagc gcagatcagt
    42421 tcgatatccc ctgcaggtat cgttggagac gtgctggatc gtgtcgaggt gccgtgagcc
    42481 gtgaggccca gcaggcgcac tgtcgttctc ctgattgccg ctgcagtctc cctcctcctt
    42541 gcatggtccc ttgactctgc ccccgctctt ttcctggcgg gatcgatgtc cgggttcgtt
    42601 gccgtccgcg cattcctctt tctccacgct gcaggaaccg tagcatcagg cgtgcgggtg
    42661 gaaaggacag cgacaccctt catcctcagg cagggaagtc ctgtcaacgt cacgtgcacg
    42721 gtgcatctcc ttcttcccca cggtattcgg gcggaagtca gtgacgttcc cccgccgggt
    42781 gcaccactga cgaagggatc gtcatctgca gaaataacgc tggccggcag ccatggtatg
    42841 aaactggcat acggactctc ctgcatctcc tgcggcaggc tttctttcgg gggtgtggac
    42901 atcgtcctcc atgacccctt cttttccctt ctcctcccct tccggggcgg tgccttctcc
    42961 catcccactc tcctcgtgga ccccgtcgga cggttcaggg cgggggaggg gtcgggtatt
    43021 atcggcgata aggattcaga ggcccggaag ctgctgcggg gatacgggat ccggtcgttc
    43081 cgcggttaca tgcccggcga tgacccgcgg acgatcgact ggaagctgac cgcaaaacac
    43141 ggaaaactgt tcgtcaggga gtacgcgggg atgatcggga agaaccccct gctcgtggct
    43201 gaccttcccg acagtgcaat gccatgccct gcctccctgc gcgatgcagt catcggttcc
    43261 gccctcgatg ccgtgcgcga gatgtgcagg atgccacggg gatgcagcct catggtcatc
    43321 tgtggcccga acctgctctc cttcctcccg aacgagagat catccgcccg gctcgaacgg
    43381 gccctgcgcg aatacagctc cccccagcag gtattacgct gttacagggc ccttgacccg
    43441 gccgttgcag aagcattcag gcagaggctg ggggagactg aaggaaacgg ggatggtttc
    43501 ccgcggaagc ttcgggagat ttattctgcg ttcattcctg caatggagcc gctccccttc
    43561 gaggtccagt gtgcacgtgc actcgcacgc cagggcgata ccgccctgca cgtcctttcc
    43621 accggatggg gagatgcgag tcaccttgcc atcctcggcc tgcaggcacg gcggcggggc
    43681 gtcgatgcac gcatcggcat tccggacagt gctatctccc ccgacttgct gcggcgcctg
    43741 aagggctggg gctatacagt tgtccgggtg atggcatgaa gccgggaatg accatggtta
    43801 tggcggttct cgcgatctcg cttgtcgcgg caggtgccct ttttggcacg cccctcttcc
    43861 ccgtcgccct cgttgcgggg gcgcttcttg cagggtcagg tctcgtcgtc gtctttttcc
    43921 atcccgagga gacagcactt ttcctttttg cgcagcctcc cgtcttcctc tcctggtacg
    43981 cctctcccct gcttgctgtc gcgctcgaag ccctgattac cattgcattt ctcgtgtcgg
    44041 caggggatac cggggtgcgc cgtggagtcg tttccgccat cctgctcgtg tccgtgtccg
    44101 ggttgtttgc cctttttatt gcggggcaca ggcacgtcct tttacccctc gtcctgctcc
    44161 ttgtcgtttg cgtgatcgta atgctcgccc tgctcggtac agcctcgcac cttatccacc
    44221 gcgtcacagg aggtagccat gaagctccag gccgccaatg attacgtggt ttcagggact
    44281 gtcctgcttg cagcggcagc cacgctcctc gtgatcgcaa cggtgacgaa caggggtgac
    44341 ctgaccagtg caaccctttt cctctgcggc gtcgcaacgt ttcttgccgg cgtgttcatg
    44401 ctcagctttt cccggagcga gccgttcgat gccgaagtcg catcgctcct ctccgttccg
    44461 ggcatgctga accagtgccg gatctgtgct gacctcgggg tcagggggga tgcgtggttc
    44521 ctgccccccg cggaaggagc aggccctctc cgcgagttca tcccggttgc cggacaggat
    44581 gtcccgccag tggtccagga ctttaccttt gttacgggtc cggacacgcc cggaatcgtc
    44641 ctcgtgccgg ctgctgcccc gctcatcgat tactgcgaga aaaaattctc cctcgttatc
    44701 ccctctgccg agggggaact catcgcggca atcagggaac tggcgcttga tgtcctcgag
    44761 ctcgccgacg gggtggagat cgtccggaac ggcgactcgc tcgtgatgac ggtccgcggg
    44821 tatcggctct tttcggggtg catggtcgtt gcatcggagt cgcccaagtg ctgcagcatg
    44881 cacccgtgcg gtatctgcag ccttgctgcc tgcatgctgg cacggggaac aggcgttccc
    44941 tggcaggtct cccatgtctc cttcgtggag ggaaaaaagc aggttaccgc gatactccgg
    45001 agccaccctt cacctgcacc cacaggtgca ggtcccggta gctcgcgttg agcctgtcct
    45061 gtccccagat cgtgtccggc ggcaggttgt ccctgaagag gaggaatttc acctggtttg
    45121 cctcccggct ctccggtatg aaggtgtgac gctgctggta tgtcgtattg tgcgggatcg
    45181 tgacggaaaa agacgccatc ctctccatcg agaggatgga actcgtgttc gtctctggat
    45241 cgaaccggtt gtcgaggaga aggatctcga caaaatatgt aacgttcctg tactcgtggt
    45301 tcccgatgcc gatgatgatc gattcgggcc gggagagcac gaggtctgtc gggtaatccg
    45361 ctgcctttcc ctccctgccc aggatataga actccgtgaa cttctccccc tccttgggca
    45421 cgacgatgac atagaccgtt gtcgcgactg cggcgattac cgctgcaacg agcaggaagg
    45481 agagggcccg gtcgagccgc gatgatccgg ccgggaagag ctcttcgcga gcttttccaa
    45541 gcatcatgcg gaaggggacg gtaaacctct catccggcgg cagctgtgcg cgccggacct
    45601 gcgcgactgc agccatcgcg agagtgaaga tgacgaggga gacaacgacg ggatccagcc
    45661 tgatgccaaa cggggtgtag ttgaggacga gcccgatgag cgggacgacc gcgatcgaga
    45721 gaccgaaaga aagggcaatc ctctctatcc cgtcgatatc cttctttccg ggaaagaggg
    45781 cggcgatcag ggcatacccg ggaacgaaga ggaccatcgg gagggcaaag atcacccgga
    45841 gcgggctgcc gtttacaacc gggaggtaga tggagaggat cgaaaggacg gtccagaggt
    45901 agacgagggc aaggtccctc ggggtgtctg ttggcgaaaa ggcaagcagg acttcaccca
    45961 gagggggaag gggtgacctc tcgtccattt ccaatcagcg gtatctgata aagaaaacga
    46021 gggctcccat gctgacagca agtgcagcaa tggccggaca ggtcgcggat cgtgtcgggg
    46081 ccgggctcgt tttttcagct gccgtggctg ccggtgatgt cgggatcgtg gtcattgtcc
    46141 ccgttcctgc aggtgtttgc ccggcagttg tctgcgcggg tgccgtcagg gtcggtgccg
    46201 gcgtggcagt gcgggtgggt gtcgcggtcg tcgtggtcgt cccggatccg ccggatgtcg
    46261 taatcccgcc actggtgcct ccgccaccac ccccgccgct gctcgtcgcg gttgccgttg
    46321 gtgtcggcgt gaccgtgtcc ccgatcacga tggtgcggga gagggcagtc tccccgtcga
    46381 ccgtgacagt cacggttatc cggccgccag aaaccccctg cacgagaaac gtgatgacag
    46441 aatcatcagg accgctcttt ttcccctgga gcgtgagacc cgccacgatc gtgtcagctc
    46501 cgggtgctgc cgttcccgac agggagatca gatcgtatgt cccggcggga atcgacccgg
    46561 tctcgctcgt ggaaaagacc cctccctgcg acgacccgac cttcctcacc tcggtgtcac
    46621 ctttccggac ggtgagaacg ttggtggcgg tattctgaag ggtggccgag agggacccgt
    46681 cccggagtcc aaaaggcatg acaaggttcc ccgtttcgaa ggagaacgca cctcccgggc
    46741 tgactgcaaa cgttccctcg atccggaggg agaacgtgct gttgtcggaa agtcccgtga
    46801 ttccaatcga gacctggtct ccctccccga tctggtccgg ggtcacggtg actgccactg
    46861 caccagctcc ggggacaaga gagaggacaa ggacaaggac cgataaataa aaaaacctgc
    46921 ctgaattttc ttttccggtt cccatgacta actattgtcg gctccctgtt atcaatccgg
    46981 tgcatgccgg ttcaccccga tcgtcacgca gagggtcggt cgcagaaccg caacggggat
    47041 cagtcaccat gcaccgatcg cgatcaaaac gcaaaagtta aaccacggtg atcacctgct
    47101 ccccgaacac acttccgaca gaaaatcgag ggtcagatca gccttttttt cccataagtt
    47161 taaatgcaac ctcgtacaag caacatatat ataaatgtgt ggaaccctcc cggggggctc
    47221 cacagggtat tggtgaaggc gggacatgga ggttaccaat aggggaacga tacacccgtc
    47281 ggggaagagg ggagcttccc cacggatctc tggatcagga aagagtctga ttatcagctg
    47341 gctggtggtt gcgatggtgc ttgccatggt tgccattccg gcatgcagtg cggcaccgcc
    47401 accgtttgcc cgcctcgacc tgaaccagac acagacgtac aggaacctga caatttcatc
    47461 gctggagacc gtcgatctca tggacctctc ggtgtcacgg gtcaccctcc attcaacggt
    47521 gggagacgac tctgacacga agaccatccc gttccccggt atccgggata tccggcgtgt
    47581 cttctcttcc gatacggctt cctggcatgg aaannnnnnn nnnnnnnnnn nnnnnnnnnn
    47641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    47701 nnnnnnnnnn nnnatgagac ctacgatgcc acgatccggg tgaacatgac ggccctcggg
    47761 gaggtcgggg gctccatcag cccggagcat atcctctccg gcaacccctt cctgacgata
    47821 ctgcgggaga ccggccttgg tcccgatgat ttcaagaaag tggtctcgta ttccatattt
    47881 gccgtcggaa acagcactcc tccccactcg acccacttct cgaagatcaa catcacaccg
    47941 ggctttggga catccgggta tgcactgcat gcaagccagg tcaccatccc ttccagcgat
    48001 ctccggggac tgctcgacgg cacgttcagt ctctatgcgc tcggtgcaga cagcaacaac
    48061 acggtggtcg ccctcgacca tgacacgatc aggctcggga gctcccccct tgccaacttt
    48121 actgccagcc caacagaggg gccggcaccc ctcgatgtcc atttcaccga cctgtcctcg
    48181 ggcacgtccc cgatgacata ccagtggatt ttcgatgacg gtgatacatc cgatgaccag
    48241 aatccaaccc atctttatac cgaagcgggg acctacaccg tcaccctgac ggtgaccaac
    48301 gatttcggtt ccagtaccga gcagaaggtc cactatatca atgtgacggc gccgggacca
    48361 acaccaaccc cgacacccac tcccagtccc acccccagtc ctactccccc gcccctccag
    48421 gcagacttca cagccgaccc cactgccggg ttcgtgcccc tgatggtcca gttcaccgac
    48481 acttccaccg gtgcccatga tacgtggtcc tggtcattcg gcgacggagg aacctcaacg
    48541 gcgcagaacc cctcgcatac ctacacgtct gttgggacat acaccgtctc gctcacggtc
    48601 aggcagggga cggggactcc ctcgacgaag acgcggacga actacatcac ggtcgtggcc
    48661 gtcccaccgc cgcctgtcgc acagtttgca gccaacgtaa cttcagggcc cgttccgctc
    48721 acggtccaat tcaatgacct ctcctcgggg tcgatcttcg aatgggtctg gacgtttggt
    48781 gacggaggaa cctcgaccga gaggaacccc gtccatacgt ataccacccc gggcaactac
    48841 accgtctccc tccgcgtgag ggggcttgga gggatcgata ccgagacaaa gacaaactac
    48901 atctcggcat tcggcgtccc gccggttgcc agtttcatcg cgaatgtcac gtccggagag
    48961 gccccgcttc ccgtcctgtt cagcgacctc tcgaccgggg gaccgacggc atggtcatgg
    49021 acgtttggtg acggtggttt ctcgaccatg cagaacccgg tccacgtcta tcactacgcc
    49081 gggaactaca ccgttaccct gacggttgca aacgactacg ggaccaatac catggtcagg
    49141 acccgctaca tcaacgtcac gggtctgacc ccgccgccgc ccggcctgca tgcagacttt
    49201 gccggggcac cccggtcagg gttcatcccc ctcaccgtcc tctttgcaga tgcctcgaca
    49261 ggcgagccga cgtcatggaa ctggtcgttc ggtgacggga cgtattccga cgagcagaac
    49321 ccggttcaca tatacagcga tgccggtggt ttcaccgtgt ccctcaccgt ttcgaacggg
    49381 acagcatctg acacggtgac caggaccgac tacatcatcg cgtcccgcag gggtggcggc
    49441 ggcggtggcg gtggtggtgg tggaggcggc ggtgcctaca tcatcaccgg aacgcccacg
    49501 cccacgccga ctgcaacacc cacaccggca gtgacccccg caggaccgct cccgctcggg
    49561 ccggatggca ggacgacgca gccggtcacg atcgtatcgt ctgacgggag ggctgcgctt
    49621 tccatcggga caggcgttgc ggtgacctgc gaggagggac tcccacccac gaccatcggg
    49681 atctccccaa tctccggaca ggacctgcct gccctgcccg gggatccggc gttcatggga
    49741 tatgcatacg cggtaagccc cgattgcacg ctcctcgacc cgggtgccat cctctcactc
    49801 cagtttacct ctgaagaatg gaccgacctc gccagccgtg acctcgtcct gatgcggttc
    49861 aacccggcga cccggacatg gatccctctc ccgacgacag tggaccaggg acgacacacg
    49921 gtgagtgccc ccatcaccca tggcggcatc tatggcctgt tcgcctgggc cccgaagggg
    49981 acccctgtcc cggcagagac caccgttgtc cccacgacac cggcaggccc tgaaatcccc
    50041 gtgacactgg ttgccatcgt catcgtggtc gtcgtggtcg cggcaggagc tgcagtctac
    50101 ctgctgaaga tccggcccgg cagaggaaat cccccggctt ccccctaggg ggatgcttga
    50161 agggaaagca atttttttat ttttacaaat gaaagaccat tccgctttgg aaaaatccat
    50221 cggaactgca gacgagggaa cagggatgca gcgcactttt ctgtcacgat ggaaaggagg
    50281 gtgccaccca ctcttttccc gggaaaaatt gttaaggcct ggttcttttt gtcagcaggg
    50341 ccacagaaaa ggcccccagg atacagacca ctccctgcag aacaggctcg gggccggcct
    50401 ggcggggttt ttctgccggt gttccctgga ttgaattgtc ggcagggccc actcctgact
    50461 ctgcccgggt aagcggcgtt accggctcca ttgatggttg gtatacttca ctgcttcccg
    50521 caggagtccc cgtgacgacc gctgttcccg gtgtaggggt tgtcatgact gctgtttgac
    50581 tgctgaccgg ggcggattcc tcccccgttc cagccccgcc cgatcccgtg cttcctgcac
    50641 tggatccagt cgtggccgtg ggtgtcaccg gcgtggtgcc agacgtggcc gggactgcac
    50701 cgcttccagt tcctgcctgg agttcaatcc ccgtgtattg cgatggttcg aagggaatgc
    50761 tctcgctaaa cgcagaagtg ctcccgatct cacggcatag ggcccgggta ccgccaacat
    50821 aaaagatgat gggggttccg gccggcatgg tgccggaaac aatcagcttt tcatcaaaag
    50881 acccgggtcc cccaaaagtt cccccttcac cggttataag ggggtttccg gccgtcccgt
    50941 tcacaatgcc ggggcaccat gcctcaacgg gtgtgccggc cggcgccggc gtacccccga
    51001 tgtatgcctg gccataaaaa aggtggggca tcaggggttc attctgggca agtgctgcgg
    51061 ggaccagcag caagaaagaa gctgtaagga tcacaaagaa taatccgagg tcacgcgatg
    51121 tcatggtatc catttagaga atggaaataa ttctataaaa agaccgcctg agtaaacgaa
    51181 gagtttataa tccatattcc agaagaaatt cttcgctggg aaaaccggaa ccccgcacag
    51241 ccccgggaaa ggtcatccgt ccccgctctc catggaactg aggggcccca ggatagagag
    51301 aactcattta ttccccggtt tttggggaaa aagacctctg tcatatttaa atttatgtat
    51361 cgaagtattt tcatgtgtcc cattattcga tttaaattag gacttacgcg gttgggttca
    51421 cgaaagatat gtgattgctt ttattttgac cagaaaagag ttcagcccga cagcatcggc
    51481 tgagcgatga agagagagat ggacggatcg ctggaccgat cgtttcgact cgtgccaact
    51541 gcggccggtc ttcagccggt ggctctccag gcggagaaac gcgaggatcg agagcaggat
    51601 atgaccccgc cggactgttt ctttacgtcc ctggcaccgt tctatcccgc agtaatgcct
    51661 gattctccga tgatattccc cgatgtttca ggcctgatcc ttgtactgct ttctctccga
    51721 ttcagaggca tccaggagat cggtagccca ctactcggtc tccccggatc cctttttcac
    51781 ccggaatacc cggatgaacc ctcacgggcg gaggtggtgg accaacccgc ccgccgacgg
    51841 gacctcgatt tcagagatgg gccggttgaa ggtttcatcg ggattcacca gccggttgga
    51901 cttgaggcgg gtgacccaga gccaggtgag ggagcggacc aacttcaggt tctcgatgct
    51961 tgagttccgg gagtcgaaga gaacacactt tggatggaac cctcgcttct tcgcctcatg
    52021 aagcatgtcc cgaaagtggt cgttcctggt tttaccatcc tcctccggat aacaggtgca
    52081 gaaatcgacc ggcacaatgg cagtaccatc cgtcaagagg gtggtgatca ggttgattcc
    52141 ctacgccagc cggtggtact tcccgctcca gtgccggctg accaccttca tccggtggtt
    52201 tgtcgagagt attgtcgtcg atgatcagga ctccctcctt taaccggatc ggtgatttcg
    52261 cctcttcgta aagcgcctcc gtgtgggtgg gtcgtctctc tgacaggcgt ttgacggaat
    52321 catgggcgaa ggatccattc tctaaaagtt ttacacatgg atgattggta caggaacagg
    52381 cctggtagat ggcgatgaga aatttgatga tgccattccg ggtgcatttg ggaggattca
    52441 caccttttat aactccattc tgggttatta caacccggaa tgtgctccct tatctgttag
    52501 ctttttcggt ttgcttcgaa ctgcgttatt cctacaaata gtaaaatttt tttcagttcc
    52561 ttcattatat tggataggtg ctgggaatgt cttattattt caaacgggaa gtgttgtttt
    52621 tttactattg attcttttat cttgctggat tggtcctgtc tcggcagaga taccggcaac
    52681 cagcgattac gaaccgggag tactgattat ctgctttacc cctgaaattg ccggaaatcc
    52741 gggctctctt tcacaggttg ccgaacgcct gcatgggggc attaattcaa caatccttga
    52801 ggactcggag gatctcggta ttcccggggt ccagtatatt gcactggacc cggatgtaac
    52861 agtagaagat gcaatctcct attacctttc agatccctcc atcctgtgga cagaacccaa
    52921 ttacatcgta catattcccg acccggtcga tggtaccacg ccgggagaga ccactcccct
    52981 caaaatgagt gatatgcacg caggtttcac atcattccgg tcaattccct cctctcttgc
    53041 atcctatccc aatgaccctg atttttccct ccaatggaac ctgaaaaaga tacaggtgcc
    53101 ggaggcctgg gaaactggtg cggggcaggg gactgtcgtc atcgcagtca tcgataccgg
    53161 cattgacttt tccaaccccg acttcgacaa caggatatgg acaaaccccg gtgaaattcc
    53221 ggggaacggg atcgatgacg acaacaatgg gtttatcgat gacgtgcatg gctgggattt
    53281 tgcgaatggc gacaatgacc cgggagatga tgaaggacat ggaacggccg tgtcctccgt
    53341 tatcgctgca cgggtcgata ataaagtggg tattgcaggg gtcatgccgg acgtccggat
    53401 catgcctctc aaggcaggaa acaagaacgg gatactctat tccaaggata ttgcaaagtc
    53461 aatccgttat gcccgggaaa atggagcaag gattgttgtg tgttcttttg ggaagtacat
    53521 gcccgacacc cttgaacgta cccagatcca gaagtctgat tccctgcttt tcgtctgtgc
    53581 cgccggaaac gaggggaata acaacgacgc aaggccattt tacccggccg gatacccttc
    53641 ggccaacatc atatccgttg ccgcaacaga caatggcgat tttctctgtc cctggtcgaa
    53701 ctatgggcaa agcaccgtcc atgtcggtgc accgggactc gatatccccg tgtatacgct
    53761 tgcgtccgcc cgcgtgacgg tgtccggcac ttcgtttgct gccccgcatg ttgccgggct
    53821 tgccggtatg gtgctttcga aagacccgac gctctccgtt gctcagctga aaggccttat
    53881 tctgaataat gttgattccg gtcccttatc cgggtacacc ataacgggtg gccgggtcaa
    53941 tgcattccgc acagtcagag gcctccagct gccaccggca gcgagtttca ctgcgacacc
    54001 cacgtccgga acagtgcctt tgacggtgca gtttaccgat acctcgacag gaaacccggg
    54061 ctcatggtcc tggaacttcg gcgacgggac gacttctgcc gagcagaacc cgctgcacac
    54121 gtatcataag cccggtactt attctgtctc gctccgcgtt acgaccaggg acggggggtt
    54181 ccggaccctg aaaccattcc tcgtaaaggt acaggaagca gattcacttc ctgtcccgac
    54241 tcccctccca acaaccgtcc ttccgactgt gaccccgact gaggctgctg ctccaccggt
    54301 ggcggacttc tctgcgtctc cctctttcgg gccggccccc ctgtcggtcc gtttcaccga
    54361 catatcgacc ggcaaccccg cttcgtggtc ctggaacttc ggtgacggga cgacttctgc
    54421 cgagcagaac ccgacccaca cctacacaac gccggggacc tatacggttt ctctgcggat
    54481 tacaacggat tccggagggt tcagggtggt caaatccggg ctgatatcgg tcggaaaacc
    54541 caccggtgat gcacgggctg ctgccccgtc tgtccggagt gccggaagtg gtatcccgga
    54601 cgatgtcctc ccgccgggaa cagacacgga tcccggtccc ctcaacccgg acttcgtcgc
    54661 atacctcgag tcgaggacac aggggcgaca ggaggagggg ggagcctata ccggcctgat
    54721 accgttcccc atcaacctct cacccctcaa aggacagcat ctcgatttcc cggacagcac
    54781 agtggcatcc cttccctccc ggtacgacct gcgcgagcac aaccgggtga cacctgtgaa
    54841 gaaccaggga tcttgtggga gctgctgggc atttgccata tatggttcgc tggagtccgt
    54901 gataaagtcc cggaccggga ccgagtggga cttcgcggag aaccacctga agaataccca
    54961 tgatttcgat aagggtccct gtgatggtgg aaattcagat atgtccatgg cctacctggc
    55021 acgatggagc ggtccaatca acgagacaga tgacccttac aatccttctt caccatcccc
    55081 agtctctcct ccggggctat ctcccgtgat gcatctccag gatgcataca tcgtgccccc
    55141 gagggacggg tcgcttgaca atgaaaatat caagaggagc atcatggagt atgggggggt
    55201 gtattcatcg ttctggtatc aagatgggtt ctattctgaa aacacacatt cgtactatta
    55261 caatggatca aacaagcnnn nnnnnnntag taatgaccaa aagtttaata ataaatatta
    55321 taattattca tactattatt attttccaga gcgaagaata ttcacatctg atgatggtaa
    55381 ccatgccata accatcgtgg gctgggatga taattattcc agaaccaact tccggtaccc
    55441 acctccagga aacggtgcat tcctggcaaa gaacagctgg ggaacagggt ggggagataa
    55501 tggctatttc tggatttcct attatgatac atctcttgga aaggaaggat ctgtgggaac
    55561 tccccttaat cgatattatg atcctaatag cgccttcaat tcctcccccc tggacacgta
    55621 cgattacatt taccagtatg accatctcgg atggaccaat gctgacggtt acaatacaga
    55681 taccgcctgg tatgcaaaca ttttcacggc aacccggaac gaggagcttt ctgccgtggg
    55741 gacgtatgtc tattctcccg ggtcgcagta cgaattgacg attttcaagt tcccatcagc
    55801 gaatgaccca tggggaacgc ctgtctcaca taaaacagga acgatcgata tccccgggta
    55861 caggacgatc ccgctggaca acgcggtcct cctctggccg ggttacaggt tctctgtcgt
    55921 tctgaaactg acgactccca actggactta ccctgtcccc ctcgaaatgc ctataccggg
    55981 ttactccagt aaagcgactg cttcgcgggg acagagctac atgagtaaag atggcgtaat
    56041 ttggaccgat gttgtagatc ggtattccaa taccaatgtc tgcctgaagg cctatacgcg
    56101 ccggatcgca ccccccgtcg ccggattcac ggcgacaccg gaagaagggc ccgctcctct
    56161 cgtggtgcag tttaccgata cctcgactgg aaacccgacc gtctggtctt gggacttcgg
    56221 ggacgggatg aagtctgccg agcggaaccc gcgg
//
LOCUS       DAOOJU010000012        52242 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_742_length_52242_cov_15.738211, whole genome shotgun sequence.
ACCESSION   DAOOJU010000012 DAOOJU010000000
VERSION     DAOOJU010000012.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 52242)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 52242)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52242
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_742_length_52242_cov_15.738211"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            176..868
                     /locus_tag="PK679_04575"
     CDS             176..868
                     /locus_tag="PK679_04575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC55265.1"
                     /translation="MEHVKRAFDAVAAQYDAQRKYIIPDMDGFYGAAVWAADWPGKDP
                     SILDIGAGTGLLSALFLEKFPLATLTLLDISDGMLEVARKRFAGSPRVRFVVADYSRV
                     DLPGKYDIVCSALSIHHLEHGDKRQLFRKIFRVLSPGGIFVNADQVEAPCDWLSRKYR
                     EYWDSFLALAPIDPGELESARIRRETLDKNAPLLDQVRWLADAGFSGVDVVYKNRTFC
                     VFVGKKGEDDAV"
     gene            1126..2571
                     /locus_tag="PK679_04580"
     CDS             1126..2571
                     /locus_tag="PK679_04580"
                     /inference="COORDINATES: protein motif:HMM:NF012640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I family
                     protein"
                     /protein_id="HPC55266.1"
                     /translation="MKECIFHLETLKVPFPPADPFTLFSRIGNGFGCILESVEGVPRR
                     AVRSIVGFEPPVVFTLGKNATCTGDPAIRERLSIPPTDNPVTQLRAICRQIRCRGDSR
                     TGFTGGLVGYLSYDAVTALSGGRVQAGEDGHPARFMLCTRGVVYDHVHETCILFDNSL
                     VTGDEERGNVKKEAINRLCRLRGAVAAVPPAKREERIQSSKRELPDLSSSMDQEEFGA
                     AVRRALDYIRNGDVFQVVLSRKISCPYAGDPLSLYGAIREINPSPYLYYLRFGDEAII
                     GSSPEMLVRVEGNSVQTVPIAGTRPRGKDPAGDDALAAELLSDPKERAEHLMLVDLAR
                     NDIGKVAAFGSVHVPEFMEVERFSHVQHIVSRVCGTLRPGCDRFDALSACFPAGTVSG
                     APKIRAMQIIAELERHPRGLYAGAVGYAGFDGTLECAIAIRTLVARGARVGFSTGAGI
                     VADSVPEKEFEETEAKARAMVEAVLSAGVGQ"
     gene            2568..3143
                     /locus_tag="PK679_04585"
     CDS             2568..3143
                     /locus_tag="PK679_04585"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HPC55267.1"
                     /translation="MRVVIIDCFDSFTYNLHQLVGVLGATPVTLTSDRPLSEVTAAAP
                     DRLILSPGPGRPEDSGICPDVIREYAGRVPILGVCLGHQVIVSAFGGRITRLKTPVHG
                     KTSFIRHTGEGILAGVRNPLVATRYHSLAARKDELPRDFRTVAVSEDDGCVMGVMHRS
                     LPVFGLQFHPESIMTPDGRQIMENFLSMEGS"
     gene            3143..4159
                     /gene="trpD"
                     /locus_tag="PK679_04590"
     CDS             3143..4159
                     /gene="trpD"
                     /locus_tag="PK679_04590"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HPC55268.1"
                     /translation="MQDAIRALAGGEGLSPEMARQAMGLLATGGATAAQAGAFLAALR
                     VKGETAEEIAAFCRVLEEHAITISPRVQGTLVDTCGTGGDGASTFNISTAAAIVAAAA
                     GIPVVKHGNRAVSSRCGSADVLEALGVNITLSPGDVCRTVEELGIGFLYAPLFHPAFR
                     HVAGVRREMGCHTVFNILGPLLNPARAPARLVGVFSPALLSPVAGALRILGVRKALVV
                     HGSGLDEITVSGETRVAELKGTSIDEYAISPREFGIPEYPLRDICGSGVEENASIIRG
                     ILHGQITGAARDVVAMNAGAALYAGGKVKEIGDGIELAMDAIATGSAGEKLGALARAS
                     RGGQ"
     gene            4156..4917
                     /locus_tag="PK679_04595"
     CDS             4156..4917
                     /locus_tag="PK679_04595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011842930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol-phosphate synthase"
                     /protein_id="HPC55269.1"
                     /translation="MILDAIIAATAERVARMPEDAEETVEAPRAATGFYDAVRRTKRT
                     NAIIAEIKAASPSRGIICSDIDPRGFAISMVSSGCAALSVITEPRFFHGSDTFLPAVR
                     NAVSVPILRKDFVIDPRQVAASRALGADAVLLITAVLKDRLPDFVELARSYSLEPLVE
                     VHTGRELEVALSSGTRMIGINNRNLKDMSVDLSVTKRLAPPARDCGCRVVSESGFVWP
                     CDIRRFRDIVDGFLIGSSIVSARNPQKKLEGFLFA"
     gene            4908..5480
                     /locus_tag="PK679_04600"
     CDS             4908..5480
                     /locus_tag="PK679_04600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HPC55270.1"
                     /translation="MRVKICGITSPEDAALAEAAGADAIGVVVFSDSIRSVTPEVAWE
                     IFSSVGPFVTRVCVSTTESSDDLETILDMNPDAVQLSIPLEERLPVRTICMVDTPGPL
                     PAHADAIVVDASRGTGRLFDADFAERVARESPVPVILAGGLTPENVAGAIRRIKPYGV
                     DVATGVEIAPGKKDENLVRAFVRQARGALL"
     gene            5477..6649
                     /gene="trpB"
                     /locus_tag="PK679_04605"
     CDS             5477..6649
                     /gene="trpB"
                     /locus_tag="PK679_04605"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HPC55271.1"
                     /translation="MTDPSRFGVYGGRFVPETLMAALEELERGFRTIVPGKKFQEEMK
                     YYLHEYAGRRTPLTFCRNVSRDFGCRVYLKREDLLHSGAHKLNNALGQALLAKFMGKH
                     RLIAETGAGQHGVATAIAGAVLGMQVDVFMGEEDIRRQKLNVSRMKMLGARVVPVSSG
                     SRTLKDAINEALRDWVTNVATTHYLIGSVVGPHPFPTMVRDFQTVIGNETRAQVMEKE
                     GGLPDAIVACVGGGSNAIGIFTPFLGEDTRLFGAEAGGEGPEGRHGATLCRGRPGILH
                     GTYTYLIQDAFGQILESHSISAGLDYPGVGPEHSYLRDSGRVSYHPVTDREALDAFLY
                     LSRSEGIIPALESAHAVSLAEKVATGLQKDDVLVINLSGRGDKDVSQVSSMAGDLL"
     gene            6646..7440
                     /gene="trpA"
                     /locus_tag="PK679_04610"
     CDS             6646..7440
                     /gene="trpA"
                     /locus_tag="PK679_04610"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: protein motif:HMM:TIGR00262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HPC55272.1"
                     /translation="MTSRIGLAFSGAGRPLLVACLVAGDPDERTSLELMKEAETCGAD
                     IIELVMPHSDPVADGPVMQKAMQRALSAGTTPDTLFSQIRNFRSVSKTPLLVLTYANI
                     VVQRGIVTFYREAAEAGADGIAIADVPLEESDPFCVAARNEGIDPVLFVSQTTSRERL
                     ERIVAGAGGFLYLVAVLGVTGAREQIDPRVIGHIRAVKAASALPVVPGFGIGTAGQVR
                     ELVRAGADGVIVGSAIVREIERTLEDPFAMREAVGGKVREMASALR"
     gene            complement(7426..8190)
                     /locus_tag="PK679_04615"
     CDS             complement(7426..8190)
                     /locus_tag="PK679_04615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HPC55273.1"
                     /translation="MKTIGPHFMDLTRYEYLSPSDQSRGLPAPPLEKPVPPDGPFIPL
                     PPPGSIRVPPLDLRRAIEARRSIRHYERDPLTQEELSYLLWCTQGIVQVVDPYYTLRN
                     VPSAGGRHAFETYLLVNRVRGIKPGIYRYLAFSHRLLPVQTGPETADRVMAACLGQAF
                     VRSSAVTFLWDCVVYRMAWRYAERAWRLVHLDAGHVCQNLYLAALQIGCGTCAIGAFD
                     DRMMAGLLNLDGDDEFVIYCAAVGRLPVRRDTSPEG"
     gene            8404..9582
                     /locus_tag="PK679_04620"
     CDS             8404..9582
                     /locus_tag="PK679_04620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HPC55274.1"
                     /translation="MIREILRVTERPDIISFAGGLPSPAFLDAAGVARAAGEVLAEDN
                     CAALQYATSEGFPPLREWIARRYRTRFGLAVDPGEILITNGSQQALDILGRIFIDEGD
                     PVAIEAPGYLGAIQAFSQYMPVFHPVPLGTEGPDPGEFSRIARTEDPVMYYAIPNSQN
                     PSGISYSTRRREEIASIISDSETVLVEDDAYGEIQFSGDKRPSFSRLLPRDKVILLGT
                     FSKIFSPGMRLGWLCAEGEILDHAVTAKQASDLHSNILAQRILYRYLQCNDIDAHISR
                     IKKAYAARCSLMLHLMDELFPGEVTYTRPDGGMFVWLTLPHPLSAMDLYRRALAENVA
                     ILPGTPFYTNGAGDRGVRLNFSNADEEKITEGMTRLARVLDAYTRECRKGQSSPHPET
                     "
     gene            complement(9601..10236)
                     /locus_tag="PK679_04625"
     CDS             complement(9601..10236)
                     /locus_tag="PK679_04625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55275.1"
                     /translation="MRLSPAILVISLCLLALSSPAGAAVVARDMRVEPAGDLLKAGDP
                     VNLTALAEIIPSGASTFSESHTLSFSSGLSNARWEIIVTVDGKQAAVIRKDGARVFLN
                     GYLLSYPTTRDVGLVIGLRGDTPPDLPDEKVILLEWEELNAGGEAVTGSVFQVSRATG
                     PLSPTGPSPSQPTITTYPSGPAPTEIPFPTVSLLLALCLFPAGAVFRKWWG"
     gene            10309..10731
                     /locus_tag="PK679_04630"
     CDS             10309..10731
                     /locus_tag="PK679_04630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55276.1"
                     /translation="MDIRFCARYIGDGHPPTNRFCRSCDCPACEELWQKVVSLAHSCR
                     DDPVPLPPTRAVLIPHPSNPAMARMRVNVTWTLPKEDFLHFISTGRAGMGKKGDRENP
                     RSSPSMTRQEPYVRAIVEALGGWDIPEIARVKRIQKGE"
     gene            11003..12691
                     /locus_tag="PK679_04635"
     CDS             11003..12691
                     /locus_tag="PK679_04635"
                     /inference="COORDINATES: protein motif:HMM:NF028237.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal 7TM
                     domain-containing protein"
                     /protein_id="HPC55277.1"
                     /translation="MILTLMAGFCLACAFITFGLGVYVIARNPGSLVNRLFLLSMLLA
                     AYWALGEFLIWQVRTPENIGFYLKASSFWPMVIAVFFHFIVVYCGHPLSRKDNSWALI
                     MGIYAPSLALSLIGLLTDDLYTVIFREGYGYVYTPVIGSNANLLESSYILAVMLLSLF
                     VVFISWKSETRGKEAYQKRLVGLGVLTVIASGALSALVLPALGIYTPNMVFLGIAVFS
                     LLMAYAIHTQGLFVVTPEMAMSQIMALIPDAIVITDGTGKITDANDAVAGILGIPRED
                     VSGRDIGEVFGGKSSGSLMDTVLRRGRVTDIEAEIDGGQHRVVSISGARVNNPEGGPA
                     GIVLVIRDITGRKARESALRIANEKISLLTRLTRHDISNLVTALSGYLELMRGDCDRY
                     INPAIQTVQRITEYLQFSKQYQDIGSTRPEWQPLAGIVARAIGEIHAEGLEITVDVPD
                     VEIFADALVYRVIYALIDNTIRHSGGATKVRINTEKGEDNALTVVFEDNGRGIGEKDK
                     ELIFQYGYGSHTGLGLAISRDILALTGLDVKETGVPGKGARFEILVPAGAWKER"
     gene            complement(12693..12914)
                     /locus_tag="PK679_04640"
     CDS             complement(12693..12914)
                     /locus_tag="PK679_04640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HPC55278.1"
                     /translation="MQTRIREFRTKRNMTQAELADRVGVRRETIVFLEAGRYNPSLRL
                     AHRVAKELGTTIDTLFSFGDEDDYVVREE"
     gene            complement(12938..13369)
                     /locus_tag="PK679_04645"
     CDS             complement(12938..13369)
                     /locus_tag="PK679_04645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55279.1"
                     /translation="MVAMKKDNRGLFKTRTWLVWMFLAGLFMLSAGIVGMSLLSPPAG
                     GTFSSAFISMGAVLIVLSGLKLWRGEGDSLQDERTRKIGAYGLSWSWFLTFIVLFVVF
                     WADYLGVWSPDAATLSVLLILLMGISARAFQIYLFRRGDVD"
     gene            13431..13892
                     /locus_tag="PK679_04650"
     CDS             13431..13892
                     /locus_tag="PK679_04650"
                     /inference="COORDINATES: protein motif:HMM:NF020549.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1894 domain-containing protein"
                     /protein_id="HPC55280.1"
                     /translation="MPRPESNGGRGLGTARDRFRTRQGITPWCRKKLIHAVTISASMP
                     GDICFNRFWSAILLKNSTPRRCDNRVKKVCREYYVISPGALFRGVPIQIPAPMLVGID
                     EENKRLLVPFRKPCYGLSLYVIESDSREIEEIRKELAGMEPHIPVATRPSK"
     gene            complement(13979..14398)
                     /locus_tag="PK679_04655"
     CDS             complement(13979..14398)
                     /locus_tag="PK679_04655"
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine-phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HPC55281.1"
                     /translation="MTSKLVEYFNKQPRLGILATSGRDGRVDVAVIGSAHMTDEKTVV
                     IGLAKNRTLACLSENPHAVYMIVEPGKSIMDWKGVRVYLEAKEIARHGPALEGLKDQI
                     AKVAGKDAAAMMAAAVTFRVVEVRPLVDMGQGWEKSI"
     gene            14555..16834
                     /locus_tag="PK679_04660"
     CDS             14555..16834
                     /locus_tag="PK679_04660"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC55282.1"
                     /translation="MIDRLFRRYPLSTYLALAIFCILVFAVAGLVAISYVSMERTLSD
                     NARSVQQQTENNLVAVLKTKEEGLRLFEESLNREMEAAFVPFLAEYERAGGDPGRMDL
                     PAVKREIGGDMELYVIDANATIVATTYSPELGLRFGDYAPYFVGYLNGIRLSDGFFPD
                     RIVSEKSTGALKKYAYRTTPDHAYILELGLPVTMPEVPTFRYPDRDLIMEVEKANPYL
                     SGVRIFDTTLRERIDDTSVEVTDPVLKETLGHILATRSSMDAAGGKPGILTRYLFVDL
                     RDNKSGSDVSRIIELNYTMLPVTKALERALVFHILIGVIFLSGCALVAFLTIRKFTRP
                     IETMVGDLDQITRGDLDHPISPPLGKDLLRLQESISRMVVQLKKTLEAVRKSEEDFRT
                     LVQGANSIIMRCAPDGKILYMNPFGFGFFGYAEKEIVGKRIHETVFPPPAGQGDVAES
                     PAQEYHPFFSLSECKMHTKNGQDVWVAWTHKPLYGREDTPSEILSIGNDISRLKQAER
                     EIQELNARLEQKIVERTRQIVEANRNLEAFTYSVSHDLRAPLRAISGYSSILLSALSD
                     LPSRERRYLEQIQRSSHKMGELIDDLLTFSRLGGQALKKKTLNPADVVEEVLLDFRGE
                     IQKRNIEVRVLDMPPCSADRALLRQVYYNLVANAIKFSRSRERPIVEIGARFHEGLPA
                     YYVRDNGIGFDMRYSAKLFGVFERLCDTGEYEGTGVGLAIVKRIIEMHGGRVWAESEP
                     DKGATFFFTLGGETGEKKE"
     gene            complement(16887..18002)
                     /locus_tag="PK679_04665"
     CDS             complement(16887..18002)
                     /locus_tag="PK679_04665"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC55283.1"
                     /translation="MFTQRILLAMVVLAALISSTAMAEMTIQASIETGKGFSQTGSIY
                     VASTPAGASAILDGGAGSLLTPGTFTGVEPGMHVVKISRQGFFPRYANVKVTAGSTEN
                     VIVTLDPVSNPGGLSISSDPRGASLYVDDRYMGKTDQVVGNLAPGAHTVRITEAGYLA
                     WEKSVTVTGGTITPVSARLDPEISPPTGDILVASAPPGAAVFINGDYRGSTTPDDLLD
                     INDLSPGQYTLVVRKPGYLDFQTTVSVEPGGVLQVMAPLAGSNKGIASAEITSTPAGA
                     DVFINSAYAGVTPLSVNDVSPGNYTVEVRLDGYSPFSTSGNVMAGQDIRIFATLQPLP
                     TQTPTRSTGPGTFSLLATVCLSGFLGIFVLKTRRKKD"
     gene            complement(18091..18840)
                     /locus_tag="PK679_04670"
     CDS             complement(18091..18840)
                     /locus_tag="PK679_04670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC55284.1"
                     /translation="MRGNAPVLSRVSLAIREGEHVAILGPNGSGKSTLVKTITRELYP
                     VLDGAGDVIFRFQGREVWDVFALRSSLGVVSPDLQMQYTRGVCGRDVVISGFFSSIGL
                     FHHHVTPEMEERAENTMRFLGIDRLAGRPMDTLSTGEARRFLIARALVHGPRTLILDE
                     PTNSLDLAALHAFRKVIRDIARSGVGIIMVTHSLHDIIPEISRVILMKDGRIRMDGRK
                     EDVLTDRNLQDLFGVPVTVRQENGYYYASGY"
     gene            19086..20279
                     /locus_tag="PK679_04675"
     CDS             19086..20279
                     /locus_tag="PK679_04675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HPC55285.1"
                     /translation="MDQKVPGTELADRMRRFRERMDRMQPDWEMAVFFGKINLYYLTG
                     TIQDGMLIVPRDGPEEFWVRRSFARACIESDFPVIRQMASFRDAGKGIARVPETVHIE
                     TGIVPVGLWELFRKHFPVRAAGSLDAEVAMTRAKKSPYEIALLRRAGEIHRTVLEDDV
                     PGILREGMSEAAFASAVYERMVSLGHQGIVRFGSFNTEIEVGQVAFGENSLYPTYFNG
                     PGGCRGMGPAAPVLGDPERTLKRGDLVFIDNACMVGGYQTDKTMNYVFCGSIPREAEE
                     MHDRCVALMEEMASMLVPGAVPSTIYASIMGSQDPGFLEHFMGHAEPKVRFLGHGVGL
                     VVDEPPVIAMGFDEPLEEGMAIALEPKYAVPGLGLVGIENTYLVTCRGGESITGSHPG
                     LIPVS"
     gene            20439..21734
                     /locus_tag="PK679_04680"
     CDS             20439..21734
                     /locus_tag="PK679_04680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55286.1"
                     /translation="MTGIRRSRCLLVAMILLLIAGAAAAATTAEKAASYVGVTSVSIE
                     PGVLMQDDTGTIVIEIKNSGSDPVSIARAEILSSDIEVLNYQTYDSVGAIGPGNTMKF
                     TFHVRAGVRDGVYFPMFYLDFTDAGSLRYPIALEVESSPVSVSVIDAPGSFSPGTKNK
                     VVLSVNNPRKNTVNSVTVTPGGDGIRTTQGSVFIGTLAADEAKSVTFEVWAEKETALA
                     FDVSYRNGLNTHHSVITIPVTIGGRETAAELVVNNVEVTRNGLLVTIGGDVTNAGLED
                     AKAVKVTVGSPATPTDPNPVYVIGSLEPDDFSSFEVTCTVRGDDSVPLVIQYRDTEGN
                     LFEKTIPVSIRAGAGGSSGTGNPAGITQGSSPVQLRPGGVIRVWQRCRENTRDRDCGH
                     HRCRGPGHRCMAEGIPGIRGRDYPEAQAGMKDRAGRFDH"
     gene            21712..22386
                     /locus_tag="PK679_04685"
     CDS             21712..22386
                     /locus_tag="PK679_04685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55287.1"
                     /translation="MPGDSIIELCGVTKIYSLPAGDVVALDRVSLTIENGEFVAIMGP
                     SGSGKTTLLNQLGCLDRPTSGDLFINGRNTREMNDRELTSLRLNTIGYIFQRFNLIPL
                     LSAYENVEFPYLMKHRRPDSSGRVGELLAQVGIDRAMATHKPPELSGGQQQRVAIARA
                     LVNDPHILLCDEPTGNLDSVTGQQIMEMLTDLNRKGRTIVIVTHDPGVARYAQRIVTV
                     RDGRVA"
     gene            22383..>22600
                     /locus_tag="PK679_04690"
     CDS             22383..>22600
                     /locus_tag="PK679_04690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55288.1"
                     /translation="MKDIILQLALRSIRIHFLRSVLAALGIVIGVVAISSMGMMGANM
                     TLSVTEELSKMANIVVITAASGSERGPGG"
     assembly_gap    22601..22700
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <22701..23731
                     /locus_tag="PK679_04695"
     CDS             <22701..23731
                     /locus_tag="PK679_04695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HPC55289.1"
                     /translation="ANIVVITAASGSERGPGGFGGGSDEKISEEDFQDIQKIAEKYGL
                     VYVVYRESDRIKVGDREGRSTIYGLDEDVMRRIFTLSDGAFPKSTSSVIVGPTLAGRY
                     DLKVGSRIRIGDEDKGATTTVKVVGILEERGMSNDINSDMAIIGSEKLFTGIYGNEGE
                     YNQVNLILNDINDSQKARTEILEKMNRKKTRVNVQDSSRMLESITSTLGTMTTFVMAI
                     AGISLLVAATSIFNVMMMSVTERVREIGIMRSIGAQKSEIRRMFLYESVVLGLVGAGI
                     GAVLALGIGWVVVLAMVGSTDYFFLPESLVYIPFAMLVGIAVCILSGVYPAWRAADLD
                     PVEALRAE"
     gene            24266..26236
                     /locus_tag="PK679_04700"
     CDS             24266..26236
                     /locus_tag="PK679_04700"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HPC55290.1"
                     /translation="MEFIPAVSVLILISIVFIFIAQKFRLPSVVSFLVIGMLVGPFGL
                     AIISDQEVISSFGEIGIILLLFTIGLELSFEDIARFWKVIFVGGFMQVCTTIIVITSI
                     TAVLGFPFNEAVFFGFLVSLSSTAIVMRVLQERGSVETLEGTTLLGILIFQDLAIIPM
                     ILITPLLIGQTGPSYEQLPLGIAKVILIITLIIVASIWLIPALLDRVSRERNRELFLL
                     TIAGICFTVAYLTNAAGLSLSLGAFIAGLVIGESEYSVDALSDILPFRDLFAGIFFLS
                     IGMLLDTRVVLTYFPIVILVIVTILGVKFLTGWLSVASMGLPPRVAILAGFSLCQIGE
                     FSFVLASSGLQSQLISIATYQIFLSGAIVTMAATPFLMGAAQPVTDLIYRRVPVRVKD
                     REKPGEELKREVSGHVVIAGFGTAGAAVARAAEIAGMQCHVIDLDPDAARREKEKGIL
                     FTIGDAKKDEILTHAGIGRAAILFVTVLPAKQAEIIVRRARRLAPGLPIVALGGSPGD
                     IPVLFSAGADEVISIEYEGALRLFARALARFGLSEDEVDPLLSRIRAHTYRGITPRSS
                     EGLPLGKIERRLEEHHIFSVPAGKGTQMAGKTVGELDELLPPDVSLVAIRRGGRTLAE
                     VTGDFVLEEGDTLLFSGPPGRAGEVAFLVSGE"
     gene            complement(26265..27038)
                     /locus_tag="PK679_04705"
     CDS             complement(26265..27038)
                     /locus_tag="PK679_04705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HPC55291.1"
                     /translation="MDTELRDRFIALWDRYFPSCELPITFELSGRDSGLPEAKPPGKW
                     RCVVCDLSRVRKGRSLLLGSGSLSCSGAQYYMGYVEERSPDFRYFLSTGKPGSVRGER
                     YKKSPELVDALTARSTFLPAGSRKYLFRRWDTLSDADCPDVVVFFARGEVLSGLFTLA
                     NFERPDPCGVTCPFGSGCSSIIHYPLLEAKEERPRAVLGMFDPSARPCVPHDTLTMAF
                     PMNLFSRIVDAMEESFLTTGSWEKVRMKIGEGAACRKTD"
     gene            complement(27105..28013)
                     /locus_tag="PK679_04710"
     CDS             complement(27105..28013)
                     /locus_tag="PK679_04710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HPC55292.1"
                     /translation="MHVHQHEKSLKIAVLVTFVFFGVELAGGFLTGSLALISDAGHML
                     VDGSALLLSLGAVVVARSLPTRSRTFGYHRIEVMVALVNGLVLIGLCFLIAQEAVGRL
                     FSPAPVYSTGMLVVGLAGLSVNIFLVWLLHGSPDLNIRSAFIHVLGDTLSSIGVVGAA
                     AWIALTGQVLADPLISLAIVIVILATSLLMVRDCMVILLQFAPRDVDFEQMVQDILNV
                     EGVEGVHNIHLWTLCSHINVLDAHVYSCEEDPRRIASIRSEIRDRLARYNIHHSTLEF
                     ECEECPDCRIVRDLAHPAPENPPANH"
     gene            complement(28110..28808)
                     /locus_tag="PK679_04715"
     CDS             complement(28110..28808)
                     /locus_tag="PK679_04715"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HPC55293.1"
                     /translation="MTQTGKAPTVLGLIASPRGKESNTRRLVEAVLQGARDEGAKTDL
                     VDIYALEIGYCNACGTCYATGECTLTDDFPELFERMMGADGLVLGAPNYVDSIPAPMK
                     AVFDRMADAIHCRMFTGKFGCSVCTAGGSNQDRIVEYLNHVLNALGAVAVGGVGVAVA
                     SDPSALGRAEKDARDLGKTLVGAIRGKYTYPDQEEMLRQRRDYFRQLVLWNKDRWPHE
                     YDWYVRMGWIDPGK"
     gene            complement(28913..29698)
                     /locus_tag="PK679_04720"
     CDS             complement(28913..29698)
                     /locus_tag="PK679_04720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55294.1"
                     /translation="MNSRLFFPFLAIFTLAFLAVAGCLSPSPPTAVSETTTLPTLPPP
                     PGTVVTETETPVIPAFTPAPTLLSSEDINLHFIDVAFGSGNIFLERLPLSTRRTTISL
                     NAGRDSDRETIEAFILKFNALSQSNKLFENTKTGQSGDIRIKFLPPDGLKAVDLSSEV
                     GWLNREFSCDGMTCAKIRGYDIYINDQMEGDMRTHYLLRALLYTLGFKGDSLRYRDSI
                     FAFPENNATSLSFLDEKAVQVMYGLGMDNGMTVDDVKRVLFFR"
     gene            29936..30241
                     /gene="eif1A"
                     /locus_tag="PK679_04725"
     CDS             29936..30241
                     /gene="eif1A"
                     /locus_tag="PK679_04725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor eIF-1A"
                     /protein_id="HPC55295.1"
                     /translation="MVFDQSTPEGMETIRVRLPKKRNREQFAIAELMLGSNHIRVRCI
                     DGVTRMGRIKGKIKKRAWIREGDTLIITPWSFQDEKCDISYRYTRPQVDWLRRNRYL"
     gene            complement(30452..31081)
                     /locus_tag="PK679_04730"
     CDS             complement(30452..31081)
                     /locus_tag="PK679_04730"
                     /inference="COORDINATES: protein motif:HMM:NF018446.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022841 - potassium ion leak channel
                     activity [Evidence IEA];
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HPC55296.1"
                     /translation="MERIGKSRIEALSDGIFAFAMTLLVLSLTVPEIPRDQAPFLLPG
                     KIAGLLPEFMLFVIAFFVLSGYWISHHRILGKIRYVDGMLVRINIFLLFSIVLIPFTT
                     SLSGDYTDVPEAVLLFHVNLLASSLLLAGMTVYIARKRDELAPGAAGGNGEGKARTVI
                     SPLVILLAIGVSFLDPAGSMWCYALIPVLLIVSGPLRRIISGHAGTPDK"
     gene            complement(31188..32447)
                     /locus_tag="PK679_04735"
     CDS             complement(31188..32447)
                     /locus_tag="PK679_04735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HPC55297.1"
                     /translation="MAEPEKVLGMPAEKGRWLLVAIGLVINLCLGTIYSWSVFVGPLT
                     AYFSAELGQTVTANEILLPFSVFLAFFAIAMPLTGKYIETLGPRRVTVIGGALTGLGW
                     LLASTVTSVWMLYIVYGIIGGVGVGIAYGVPVAVAARWFPDRRGTAVGLTLLGFGFSA
                     FLTANIAGYLIEAAGVMNTFRVFGIAFIVLIVLLALPLRFPRPGWKPAGWTPPPVKPG
                     EEICECDRAAMVRTPAFYGLWSCYFIGCLAGLMAISIAKPVGTEIGIETGLATLLVGF
                     FAIFNGGGRPLFGALTDRITPRNTALVSFVLIAAVSVALWQAPSVPVYVAGFAILWGC
                     LGGWLAIAPTATASYFGTCDYPRCYGIVFLAYGAGAIAGPQLAGFIKTTTGTYMGVFP
                     YVLVLALLGFTLALVLMKPPRVTAVQR"
     gene            complement(32479..34380)
                     /gene="acs"
                     /locus_tag="PK679_04740"
     CDS             complement(32479..34380)
                     /gene="acs"
                     /locus_tag="PK679_04740"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003987 - acetate-CoA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0019427 - acetyl-CoA biosynthetic process
                     from acetate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HPC55298.1"
                     /translation="MAESFDVPLSDSEKVYIPDPSYRQNAWTKDYKKAYSEFLADPEG
                     FWEKQAHHFDWIRKWDRVLDWNYPYAKWFVNAKLNITANCLDRHVANHRRNKVALIWR
                     GEEGEERIFTYKKLFTEVCRFANGLKRLGIRKGDRVCIYMPLVPEQIIAMLACARIGA
                     VHSVVFGGFGVAALNMRIRDAEARVVITADVTIRRGKTIPLKTIVEEAIINAPSVEKV
                     VVLSREIEQPVELHREMEVDYHEIMEGVPPTCEPEVMDAEDPLFILYTSGSTGAPKGI
                     VHTCGGYMVGTGYTSQHVFDLKDTDVYWCTADTGWITGHSYVVYGPLAVGATVVIGEV
                     VPDYPDPGSFWKIIQDLGVTVFYTAPTAIRMFMKVGEEWPNKYDLSSLRILGSVGEPL
                     NPEAFEWFYRVIGKQKCPIVDTWWQTETGMHMITTMVGEPMRPGFAGKAIPGVVADVV
                     DKAGNPVAPGNGGFLVIKKPWPAMFRTVYKNDERYRTYWNTIPNCYTAGDLAVKSKTD
                     DYIMIIGRADDIIIVAGHNIGTAEVESALVSHQAVAEAAVIGKPDPMKGNIIKAFVIL
                     RVGFSPSEKLKTDLIYHVRMTLGPIAMPSEIEFVDKLPKTRSGKIMRRVLKAKELGID
                     PGDVSTLEE"
     gene            34848..35834
                     /gene="argC"
                     /locus_tag="PK679_04745"
     CDS             34848..35834
                     /gene="argC"
                     /locus_tag="PK679_04745"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HPC55299.1"
                     /translation="MDVAIVGASGYTGGDLIRLLLAHPHVRVVCATSRKLAGKPVVSV
                     HPHLKGLIDLSFSNPSPDEMDADVAFLAVPHTAAMAYVRPLLARGMKVIDLSADYRLP
                     REVYEKVYGVTHTDYFPAPYGIPEIHRDSYKNADFVSNPGCFPTGATLAAAPLARLAH
                     TVIYDSKTGVSGAGDNPSATTHYPNVADNVNPYKWTSHRHLAEMRQELAALGSRARCY
                     FTPHLVPVNRGILTTAHILLHEPLDQADVDELYRKYYDGEFFVRLQNPVLAAVRGTNF
                     CDIRAESEGERVVVVSAIDNLGKGASGQAIQNMNIICGFDEREGLTGAGLLP"
     gene            35848..36321
                     /locus_tag="PK679_04750"
     CDS             35848..36321
                     /locus_tag="PK679_04750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC55300.1"
                     /translation="MLVRDVMTKNPVTVSAGATIREAAALLRERNIGGLPVMDGDRLV
                     GMITESDILRLLETGRISDDLWLPSPLEVIEVPIREFINWEKTRHALTAIGEKEVRTV
                     MSHPVVTIGEDADIEEAASLMLSKKIARLPVMRGNTLVGIVARSDIIRGIARTET"
     gene            36339..37490
                     /gene="argJ"
                     /locus_tag="PK679_04755"
     CDS             36339..37490
                     /gene="argJ"
                     /locus_tag="PK679_04755"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ornithine
                     acetyltransferase/N-acetylglutamate synthase"
                     /protein_id="HPC55301.1"
                     /translation="MKSICGVEGVTAWGVKEGKFGLALIRAEGEAAGVFTSNLMKAPV
                     IRLMEERIRSGRLAAVVANSGCANAYTGKRGYSDAREMAAIAAEAVGVSPGEVGVAST
                     GVIGRYLDLPLIRDQCHRVAPLLSRSEEAETRAARAIMTTDLTEKHALVRRETFSVGG
                     ITKGSGMIAPNMGTMLAFIYTDAEVPAKNLRGILRDAARRTFNRVVVDGDMSTNDIAL
                     CTATGTAGRVPEKEFSMALEECCRALAIQIAMDGEGATKLLEVTVRGAPGEEEAATVA
                     RTIVSSPLVKTAVYGADPNWGRVIAAAGRAGIAFDPENVDLWMGDGRESVPLVKGGEI
                     VVDLARAKSLMMGKKVVFVLDLASGNGEATAWGCDLTEKYVEINGRYTT"
     gene            37487..38362
                     /gene="argB"
                     /locus_tag="PK679_04760"
     CDS             37487..38362
                     /gene="argB"
                     /locus_tag="PK679_04760"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011450157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HPC55302.1"
                     /translation="MKREDVLMEALPYIQKFHGKTMVIKLGGHAMVDPAILEMAIRDA
                     VLLQLVGIRLVLVHGGGPEITDKMKAMGKEPRFVAGLRITDEETLEIAQMVLVGKINS
                     NIVSLIAKSGGKGIGLSGNDGNLIIARRMVPKRVRVEGKEREIDLGHVGEIEEINPSI
                     LHTLLDSGYIPVIAPIAIDRNGQSLNINADTAAGEIAIALHAYKLINMTDVDGIMDAS
                     RSHVFRRLGVAEAESLMEEGTVSEGMIPKVSSIVRAVNNGVSFGHVINGNIPHNLILE
                     MFTDEGVGTMITARD"
     gene            complement(38419..38703)
                     /locus_tag="PK679_04765"
     CDS             complement(38419..38703)
                     /locus_tag="PK679_04765"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HPC55303.1"
                     /translation="MPIEALRTEINRIDEQIIDLIAERQHLAARMAQVKMAEGLPVHD
                     DKRTHEVLEHAYNYAVEKGINPLSVRKIFGLLIEMSEEKQRECQGDGNLP"
     gene            38803..39414
                     /locus_tag="PK679_04770"
     CDS             38803..39414
                     /locus_tag="PK679_04770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50"
                     /protein_id="HPC55304.1"
                     /translation="MLERITRRERSDLLIAWIAISIAFSLIFIRGGVTLETFLVFLLI
                     SMVTVGIGFILHEMAHKFTAMRYGYWAEFRKDNLMLLVAVAMAALVGVVFAAPGATVI
                     YGTYITREQNGKISAAGPAVNLVLCAVFAVLSGAAGLLSIPLLSLIGMVGLQVNAMIA
                     AFNMLPVSVLDGKKVLAWNPAVFAVLIVTAFGILLASYFTPLF"
     gene            39509..40204
                     /locus_tag="PK679_04775"
     CDS             39509..40204
                     /locus_tag="PK679_04775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HPC55305.1"
                     /translation="MHIMEGFLPLPWAAFWWAVALPCLGFGIYQLKRILSADREALPL
                     LGVTGGFIFILSSLKLPSVTGSCSHPTGTGLSAICFGPFITSVICAIVLLFQSLFLAH
                     GGLSTLGANIISMGVAGPVAGWVVYRILRDTRVHVYLTVFCVCAIADLVTYVVTSFEL
                     ALAYPAAVGGVASSFVSFLGIFAITQVPLAIVEGIVLALVFKYIVTLKPEILIRLRVF
                     PEEKIRAAAGDAP"
     gene            40201..40515
                     /locus_tag="PK679_04780"
     CDS             40201..40515
                     /locus_tag="PK679_04780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011450133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt transport protein CbiN"
                     /protein_id="HPC55306.1"
                     /translation="MKKGYLLEILAIAAIIGFCAIFLYSSSLAGEAEFAGSDTVGSER
                     VSELSGIPLEEFHPIIPQWEPPSGEVESGLFALQAAVGGIIVGWVFGYWKGQAKVKNH
                     EG"
     gene            40525..41313
                     /gene="cbiQ"
                     /locus_tag="PK679_04785"
     CDS             40525..41313
                     /gene="cbiQ"
                     /locus_tag="PK679_04785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HPC55307.1"
                     /translation="MYEEILEDIAHNSALRETNTAVKLATGAGAILLCLLSPGFFAPL
                     FVAVTLVLALVLLARVDIHTLLHVYTAPALFALFSIAVIVLVSGGGECFWRWQPLPWF
                     ALSLSRDGINQGVLVLARFAGGTTAIAFIALTTPMTDLFAVMKRARVPDEVTDLAMII
                     YRTIFVIMAHVVQVYRAQIMRLGYSTFRESVRSFATLCGAVFIASWEAGEDLVRAMEA
                     RCYDGKFAVLGRDRPPAPLSVAAVALFFLTTGALAVTTADITLL"
     gene            41326..42498
                     /locus_tag="PK679_04790"
     CDS             41326..42498
                     /locus_tag="PK679_04790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC55308.1"
                     /translation="MGRVILEARDIWYRYPRGMEAIRGISFHIWRGEKVAVVGPNGAG
                     KSTLLLMFNGMVKPDRGIILFDNEPIRYDRAALRELRRKVGFVMQNPDRQIISPTVFQ
                     DVAFGPVNLGYSGEEVRKAVERALAQVGLQGFERRPPHQLSGGEKKRVAIAGVLAMDP
                     DVLILDEPTTGLDPSGSEDIMELLDELHHQGKTVIISTHDIELAYPWADRAILLTRGR
                     ILQEDVPDIAFGDPELVRMARLSMPTLLELYIELKKRGFSLPERKPKTVLDMLNVIDR
                     AFRNRLCYTQPGRITVLDVDAPCKVSLSEWRARHPGVSLGAMGTRAKQRAAEEKITPE
                     FTYGVIDKCILKALLGEDSMIVTTGSMAGRVRERVQEFSREFNLDIEVVMARETLE"
     gene            complement(42565..43170)
                     /locus_tag="PK679_04795"
     CDS             complement(42565..43170)
                     /locus_tag="PK679_04795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC55309.1"
                     /translation="MPVRVLGLSGSPHRHGNTETLLDAFLEGTREAGAVAEKVILKDL
                     AYSPCRGCNACHKTGNCIVSDDAIPLFDRILSSDCLAVASPIYSMGITAELKGLIDRA
                     QFLWARKFILKTMYFSDDHIRKHKGLFISTAGLSWDNVFDAAFPAVTAFFNTLGFEYY
                     DNIIANDMDRYGGIRGHPTALAEAGEKGRSVVGVIARLHGE"
     gene            complement(43172..43786)
                     /locus_tag="PK679_04800"
     CDS             complement(43172..43786)
                     /locus_tag="PK679_04800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC55310.1"
                     /translation="MEIKVLAFAGSPRRGGNSETLLDWVLQAMEQEGGVAIEKVVLTE
                     ANVNPCRGCNACEKLNKCVQRDGMDYLHDRIVDADCLILAAPIFCMGICAQAKALIDR
                     FQVFRSRKFVLKLPVVAPEKKGKRMGIFLSTAGQNWDYVFDGAVPTVKCFFHVVDIPD
                     RDIRYLMVNGVDEKGAILSHPSAKADAGRLGRDVVRELGTRMGR"
     gene            complement(43868..44509)
                     /locus_tag="PK679_04805"
     CDS             complement(43868..44509)
                     /locus_tag="PK679_04805"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HPC55311.1"
                     /translation="MCGEFGSMPVLGEPAPDFEALTTAGMVKLSDFKGKWLVLFSHPA
                     DFTPVCTTEFIAFSQIAEELKSLNVQLMGLSIDSVHSHLAWIRNIKEKMGVDIPFPII
                     ADLDMKVAKKYGMIHPGQSSTAAIRAVFFIDDKGILRAMIYYPLTAGRYMPEIIRLVK
                     SLQTTDKYGVATPANWQPGDKVVVPAPKNKEEMDKRLSEGYECKDWYLCFKKL"
     gene            complement(44516..44860)
                     /locus_tag="PK679_04810"
     CDS             complement(44516..44860)
                     /locus_tag="PK679_04810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HPC55312.1"
                     /translation="MAKDTKNLEKMIGKVPKFFRELAEKDPQMYEMVMKLEGHIWDDG
                     ALTRKTKKLIAIAIAASLRDQHAVRAQLAGAKNLGITKKEVEEALRVAFLLAGMPAYV
                     YGKAQLDEVMPE"
     gene            complement(44868..44993)
                     /locus_tag="PK679_04815"
     CDS             complement(44868..44993)
                     /locus_tag="PK679_04815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin FeS4 iron-binding
                     domain-containing protein"
                     /protein_id="HPC55313.1"
                     /translation="MVNVSKVGQVFECEICGNVVVVKEVGGGELVCCGQPMKLVK"
     gene            complement(45133..45369)
                     /locus_tag="PK679_04820"
     CDS             complement(45133..45369)
                     /locus_tag="PK679_04820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55314.1"
                     /translation="MVIDLTEKAKAGQKVGPGKYVCLDCGREMVLDKAEQDLRKCPQC
                     ACEEYQCFPMTHIRPDIKTPEDAMNPPKRGKSNL"
     gene            45525..46127
                     /locus_tag="PK679_04825"
     CDS             45525..46127
                     /locus_tag="PK679_04825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC55315.1"
                     /translation="MGFRIAGLLGSPLAGGNTAKLLDQALLGARDAGCEVERIDVGDM
                     VFRPCREIFYCREHGTCAMKDDMIPLYRTFAELDSLIVATPVMTMGIPGALKSFMDRF
                     QVFFMAKYMRNSPLVPEEKRAHRRGLYIGIAGMNVPYVFDGAKLTMKAFFSIIDVEYW
                     DELLTRDMDTIRDITTRPDIMDEAYRKGFRLGELLFEKNP"
     gene            complement(46129..46794)
                     /gene="radC"
                     /locus_tag="PK679_04830"
     CDS             complement(46129..46794)
                     /gene="radC"
                     /locus_tag="PK679_04830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HPC55316.1"
                     /translation="MKRMRDIAACDRPREKIAKKGARALSDHELIAAIIGHGTPDRDV
                     FSLAKDIAGLFSSRDGDVSYNDLVGVPGIGQSRAAQILASLELARRYLRREEARTRIQ
                     CPADILQFVADLATKSQEHFVCITLNGANEVIEKRTITVGLLNHSLVHPREVFADAIT
                     DRAAAVICVHNHPSGSLEPSQQDLAITRQLKEAGEILGIRLLDHVIVARSGYTSLRER
                     GSF"
     gene            46910..47410
                     /locus_tag="PK679_04835"
     CDS             46910..47410
                     /locus_tag="PK679_04835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HPC55317.1"
                     /translation="MATMENAMEAFAGESQANRKYAAFAEQAESEGFKNIARLFRAAS
                     EAEAIHAKKLLKAMGKISSTKENLAGAVSGETHEYTEMYPAFLKEAEAEKKSDVALVF
                     TYAMKAEEVHATLYREALNNLSHGQDMSNRTVYLCPVCGNVFLGNPPDKCPICMAVRK
                     VFKTIE"
     gene            47532..48689
                     /locus_tag="PK679_04840"
     CDS             47532..48689
                     /locus_tag="PK679_04840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HPC55318.1"
                     /translation="MPRVTVYYTQNCPYCRMAKAYLDRHGVDYMAIDVGSDREQAEKM
                     VRLSGQYGVPVITVDDEVIVGFDAERLNELFGTAQGKGGEIFDVLIIGAGPAGLTAAV
                     YCSRKMLKTIIVSENIGGQALESWAIENYMGYRMVSGADLMRKFEEQVRTEQNIHIDL
                     DRVQSLGREGESFVAQTAGGKTYSARSVILAQGKRPRKLGVEGEERYLGRGLSVCSTC
                     DGPLFRDKVVAVVGGGNSALQTAIEMSKIAREVHLVVRSTIKADPAYVKQYEERKNII
                     THLNHTVSALHGNGMLTGITIRDGRSGKETTITLDGVFAEVGWVPNTDFLGDLVPLND
                     QKEVIVDINCTTGTPGVFAAGDVTNIRTKQIITAAGEGAKAALEAYAYLTR"
     gene            49519..50886
                     /locus_tag="PK679_04845"
     CDS             49519..50886
                     /locus_tag="PK679_04845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HPC55319.1"
                     /translation="MIVYPCSSADPTGAATLEEKPDAPVNFSWTLMCGFLVMFMQAGF
                     ALVETGLTRAKNAATIVMKNLMDFCMGALSYWAVGFAFMFGTATGISGLIIGFDKFFL
                     MGEAYDVSTMELWFFQLVFCATAATIVSGAVAERIKFSAYIIYSVVISAIIYPIYGHW
                     VWGGGWLASSEFMTTLGGGYGALDFAGSGVVHAVGGFMALAGAYLLGSRIGKYKKDGT
                     PVAIPGHSITLAMLGVFILWFGWFGFNAGSTLAATELHISIIAVNTALAGAAGAMVTM
                     FLTWWRFGKPDVSMAGNGVLAGLVAVTAPCAWINPVAAVFIGVIAGVIVYMGVWFLDH
                     RLHIDDPVGAVSVHGFNGIWGLLALGLFADGTYGVYTTQGPMVTGLLYGNAGFFLCQV
                     INSVVVFAWAFGLGLILFWVLKHTIGIRVSREEELQGLDIGEHGTSAYPNFVTTEPAV
                     DGDIA"
     gene            50883..51221
                     /locus_tag="PK679_04850"
     CDS             50883..51221
                     /locus_tag="PK679_04850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HPC55320.1"
                     /translation="MKKVEAIIRATKFEEVKLALEKAGIESMTVIEVKGRGKQKGITQ
                     QWRGAEYVVDLLPKTKIEMVVDDARVETVVDTICSVAATGKIGDGKIFISTIDDVIRV
                     RTRERGTTAL"
     gene            51316..52038
                     /locus_tag="PK679_04855"
     CDS             51316..52038
                     /locus_tag="PK679_04855"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HPC55321.1"
                     /translation="MILKGMHQRKVTIFQHVRNEHGGLFEEYIRERGMDIFHVPIDET
                     NEILPFHSTHLLILGGPMSVNDEKEYPWLKEEKQIIREWVAEGRPVLGICLGAQLIAS
                     SIGAEVHPCQEERGWSSVISVNPRIFPDLPLRFRVFQMHGETFEIPHKAALVFRGENV
                     CNQGLCIGSALGIQFHVELTIRMIQDWISCLPDQEQSFILAQSRQYLPESENICRIIA
                     DRFLSAAPYDFSWVHPGNGTPV"
BASE COUNT        11252 a        14638 c        15428 g        10824 t
ORIGIN      
        1 agtgaattgt cgaatgcact ggtatcgcct cacttgacgt aaaggcaggt tcttgtcatc
       61 gccgtcggga atagggcttg gacctttccc tgcaggccta cccggggaag catctgggaa
      121 gcgatgggga atccatgcag tattatacac ctggaacgac cacctgtttt taccaatgga
      181 acacgtaaag agggcttttg atgccgttgc agcgcaatat gacgcccagc ggaagtacat
      241 cataccggat atggacggct tctacggggc agcagtctgg gcggcagact ggcccgggaa
      301 agatccttca atccttgata tcggtgcagg gaccggtctc ctgtcagccc tgttcctcga
      361 gaagttcccc ctcgccacgc tgacactcct tgacatatcg gacgggatgc tcgaggttgc
      421 gaggaagcgg tttgcaggca gtccccgggt caggttcgtt gtcgctgatt acagccgggt
      481 tgatctcccg ggaaaatacg atatcgtctg ttctgccctc tcaatccacc acctggaaca
      541 cggggacaag cggcagcttt tcaggaaaat tttccgggtg ctctcccccg gaggaatctt
      601 cgtcaacgcg gaccaggttg aagctccgtg tgactggctc tcccggaaat accgcgagta
      661 ctgggattcc ttcctggccc tcgccccgat cgatcccgga gaactggagt ctgcgaggat
      721 ccggcgggag acgctcgata agaacgcccc gctcctcgac caggtgaggt ggctcgcgga
      781 tgccgggttc tccggggtgg atgttgtcta caagaacagg actttttgcg tgttcgtagg
      841 aaaaaaaggg gaagatgatg ccgtttaggt gatcatcggc actttttttt gcaaccatgc
      901 caccagcgga gacaaggaat aatccaaacc aatgcaacca ccacggttat tctcttaata
      961 tgtctaataa aaaacaccaa agtataaata atagcattaa tgtacataaa taaacatgat
     1021 aaacgggaag aatgataccc aggtgatgcc ggtggactgg ggactgccgc cagaccggcg
     1081 gcacattcca ccagagacga agggcaaaaa aaccgccccc atgagttgaa agagtgcata
     1141 ttccaccttg aaacgctgaa agtccctttc ccgccagccg atccattcac tcttttttcg
     1201 cgtatcggca atggattcgg gtgcatcctc gaatccgtcg agggggtccc gagaagggcg
     1261 gtacgctcca tcgtcgggtt cgaaccccct gtcgtcttca ctctcgggaa aaatgccacg
     1321 tgcacgggag atccggccat ccgcgaacgg ctgtccatac ccccgaccga taacccggtt
     1381 acccagttga gggcgatctg caggcagata cggtgcaggg gcgacagcag gaccggtttt
     1441 acagggggac tggtcgggta cctctcctac gatgctgtga ctgccctttc gggaggacgc
     1501 gtccaggcgg gagaggacgg gcatcctgcc cggttcatgc tctgcacacg cggggtcgtc
     1561 tatgaccacg tgcacgaaac ctgtattctt tttgacaatt ccctcgtcac gggcgatgaa
     1621 gagaggggaa atgtcaaaaa ggaggccata aacaggctgt gcaggctcag gggtgccgtg
     1681 gcagcggttc ccccggcgaa aagggaggag aggatacagt cttcgaagag ggagctccct
     1741 gatctgtcct cgagcatgga ccaggaggaa ttcggtgcag ccgtccggcg ggcactggat
     1801 tacatcagga atggcgatgt cttccaggtc gtgctgtccc gcaaaatctc atgcccctac
     1861 gcgggtgacc ccctctctct ctatggggcg atcagggaga tcaacccatc cccctacctc
     1921 tactacctcc gtttcgggga cgaggctatc atcgggtcaa gccccgagat gctggtgcgg
     1981 gtcgagggaa actccgtcca gacagttccg atagcaggga cgaggccccg tggtaaggac
     2041 cccgccgggg acgatgccct tgccgccgag ctcctctccg atcccaagga gagggcagag
     2101 cacctgatgc tcgttgacct tgccaggaac gatatcggga aggttgcagc gtttggttcc
     2161 gtccatgtac ccgagttcat ggaggtggaa cggttctccc acgtccagca catcgtctcg
     2221 agggtatgcg gcacattgag gcccggctgc gacaggttcg acgccctgtc ggcctgtttc
     2281 ccggccggaa cagtaagcgg ggcccccaag atccgggcga tgcagatcat cgcggaactg
     2341 gaacggcatc caaggggcct gtatgcaggt gcggtcgggt acgcagggtt cgacgggacg
     2401 ctggaatgcg ccattgctat caggactctg gttgcaagag gggcgagggt tggcttctcc
     2461 acgggtgcag gcatcgttgc cgattcggtc cccgagaagg aattcgagga gacggaggca
     2521 aaggcacgcg ccatggtcga ggcagtcctc tctgcagggg tggggcaatg agagtcgtta
     2581 tcatcgactg ctttgacagc ttcacctaca acctccacca gttggtgggg gtgctcggcg
     2641 caacaccggt aaccctgacc tctgaccggc ccctctccga ggtcaccgcc gcggcacccg
     2701 acaggctcat cctctccccc ggtcccggga ggccggaaga ctcgggaatc tgcccggacg
     2761 tcatccggga atatgcgggc agggtcccca ttctcggtgt ctgcctcggg caccaggtga
     2821 tcgtatctgc cttcggggga aggataacga ggctgaaaac gcctgtccac ggcaagacga
     2881 gcttcatccg ccacaccggc gagggaatcc ttgccggtgt caggaatccc ctcgttgcca
     2941 cgcggtatca ctcccttgca gcccgaaaag atgagctccc ccgtgatttc aggacggttg
     3001 ccgtctcgga ggatgacggg tgcgttatgg gtgtcatgca tcggtccctg cccgtctttg
     3061 gcctccagtt ccatcccgag agtatcatga caccggacgg gaggcagatc atggaaaact
     3121 tcctttccat ggagggatcg tgatgcagga cgccatcagg gcactggcag ggggggaggg
     3181 actctccccg gagatggcac ggcaggcgat gggacttctt gccacgggag gggcaaccgc
     3241 agcccaggca ggggcattcc tcgctgcact ccgggtcaag ggcgagaccg cggaggagat
     3301 tgccgcgttc tgcagggtcc tcgaggagca tgcgattacg atctcaccaa gggtacaggg
     3361 gacactcgtc gacacgtgcg ggacaggggg tgacggggca tcaacgttca atatcagcac
     3421 cgcggccgcg atcgttgcag cggctgccgg aatccctgtc gtgaaacatg gcaacagggc
     3481 ggtgagcagc aggtgcggtt ctgcagatgt gctcgaagcc cttggcgtga acatcaccct
     3541 ttccccagga gatgtctgcc gtacagtcga ggagctcggg attggctttc tttacgcacc
     3601 cctcttccat cctgccttcc ggcacgttgc cggtgtacgc cgggagatgg ggtgccatac
     3661 tgtcttcaac atcctcggcc ccctcctgaa cccggcccgt gcacccgccc gcctggtcgg
     3721 tgtcttctcc cccgccctcc tttcccctgt tgcaggtgcc ctgcgcatcc tcggtgtccg
     3781 aaaggcgctt gtcgtgcacg ggtcaggact cgatgagatt acggtttccg gggagacacg
     3841 cgtggctgaa ctgaagggga ccagcatcga tgagtatgca atttcgcctc gggaatttgg
     3901 catcccggaa tacccgctgc gggatatctg cgggtcaggg gtggaggaaa acgcatctat
     3961 catccgcggt atcctgcatg gacaaataac cggagctgcc cgcgatgtcg tcgccatgaa
     4021 tgccggggca gctctctacg caggagggaa ggtaaaggag atcggtgatg gcattgaact
     4081 tgccatggac gcaatcgcca cggggagcgc cggtgaaaag ctcggtgccc ttgcacgggc
     4141 atcccggggt ggccaatgat acttgacgcg atcatcgccg caacggcgga gcgggttgcc
     4201 cggatgccgg aggacgcaga agaaaccgtg gaggctcccc gggcagcaac agggttctat
     4261 gatgcggtga ggcgcaccaa gcggactaac gcgataatcg ccgagataaa ggcagcctcc
     4321 ccatcacggg gtatcatctg cagcgatatc gatccacggg gttttgccat atccatggtc
     4381 tcttccgggt gtgcggccct ctcggtcatc accgaaccga ggttctttca cgggagcgat
     4441 accttccttc cggctgtccg gaatgccgtt tcggtcccga tcctccgcaa ggacttcgtc
     4501 atcgacccaa ggcaggtcgc cgcaagccgt gccctcggtg cagatgcagt tctcctgatc
     4561 actgcagtcc tcaaagaccg gttgcccgat ttcgtggaac ttgcccggtc atactccctc
     4621 gaacctcttg tcgaggtgca caccgggagg gaactcgagg ttgccctctc gtcgggcacc
     4681 cgcatgatcg gaatcaataa caggaatctc aaagacatga gtgtcgatct ctcggtgaca
     4741 aaacgactcg cgccccctgc ccgcgattgc gggtgcaggg tggtctctga gagcggattt
     4801 gtgtggccct gcgatatcag gaggttccgg gacatcgtgg atggtttcct gatagggtcc
     4861 tcgatcgtct ctgctcgcaa cccgcagaaa aagctggagg gatttctatt cgcgtgaaga
     4921 tatgcgggat tacgtccccg gaagatgccg ccctggcaga ggcagcaggt gcggacgcca
     4981 tcggcgtggt ggtgttctcg gattcgatcc gttcggtgac accggaggtt gcctgggaga
     5041 tcttctcctc tgtcggtccg ttcgtaacga gggtctgtgt ctcgacaaca gagtcctccg
     5101 atgacctcga gacgatactc gatatgaacc ctgacgcagt ccagctctcc atccccctcg
     5161 aggagcggct gccggtccgc acgatctgca tggtcgatac tcccggcccc ctgcctgcgc
     5221 atgcagatgc catcgtggta gatgccagca gggggacggg cagactattc gatgcggatt
     5281 ttgcagagcg tgtcgcaagg gaaagtccgg tgccggtcat ccttgccggg ggcctcaccc
     5341 ctgaaaacgt tgccggagcg attcggcgta tcaagcccta cggggtggac gtggcaaccg
     5401 gcgtggagat cgcaccgggt aaaaaggacg agaacctcgt cagggccttc gtccggcagg
     5461 ccaggggggc tctcttatga cagatccctc gcggttcggg gtttacggcg gacggtttgt
     5521 ccctgagacg ctgatggcag cgctcgagga gctggagcgg ggtttccgga ccattgtccc
     5581 cggaaagaag ttccaggagg agatgaagta ttacctccac gagtatgccg gccgaagaac
     5641 accccttacc ttctgcagga acgtgtcccg tgacttcggg tgcagggtct acctcaagag
     5701 ggaagatctc ctccattccg gtgcacacaa gctgaacaac gcccttggac aggcactact
     5761 ggcaaaattc atgggaaaac accgtctcat cgcggaaacg ggagctggac agcacggcgt
     5821 ggccacagcg atcgcagggg cggtgctcgg gatgcaggtc gacgttttca tgggggagga
     5881 agatatccgg cgccaaaagc tcaacgtctc ccggatgaag atgctcggcg cccgggtcgt
     5941 tccggtgagt tcgggatcac gcacgctcaa ggatgccatc aacgaggccc tccgcgactg
     6001 ggttacgaac gttgccacga cccactacct gataggatcc gtcgtcggcc cgcacccgtt
     6061 tccgacaatg gtcagggatt tccagacagt catcgggaac gagacccgcg cccaggtcat
     6121 ggagaaggag ggggggctgc cggatgccat cgtcgcctgc gtcggcggcg gttcaaacgc
     6181 aattggtatc ttcacacctt tcctcggcga ggacacacga ctctttggag cggaagcagg
     6241 aggggaaggg ccggagggaa gacacggggc aactctctgc aggggacgcc ccggcatcct
     6301 ccacgggaca tacacgtacc tcatccagga tgcctttggc cagattctcg agtcacacag
     6361 catctctgca gggctcgatt acccgggtgt cggcccggag cacagttacc tgcgggacag
     6421 cggcagggtg tcctaccacc cggtgacgga cagggaggca ctcgatgcat tcctgtacct
     6481 ctcccggtcc gagggaatca tcccggcact ggaatcggcc catgccgtat cccttgcgga
     6541 aaaggtcgcc accgggctcc aaaaggacga tgtcctcgtg atcaacctct cgggccgcgg
     6601 cgataaggac gtatcgcagg tctcttcgat ggcgggggat ttgctgtgac atcgagaata
     6661 gggctggcgt tttccggcgc aggccgaccc ctcctcgttg catgcctcgt tgcaggtgat
     6721 cctgacgaaa ggacatccct tgaactgatg aaggaagccg agacttgcgg tgcagacatc
     6781 atcgagctcg tgatgcccca ctccgacccg gttgcagacg ggcccgtcat gcagaaagcc
     6841 atgcagcgtg ccctgagtgc cgggacgact cccgatacgc tcttttccca aatccggaat
     6901 ttccggtccg tttcaaagac acctctcctc gttctcacct acgccaacat cgtggtacag
     6961 aggggaattg taacgtttta cagggaagcg gcagaggctg gagcagacgg gatcgcgatc
     7021 gccgacgtgc ccctcgagga gtcagaccct ttctgcgtgg cagcacggaa tgaaggtatc
     7081 gatccagtcc ttttcgtcag ccagacgacg tcgcgtgaaa ggcttgaaag gatagttgca
     7141 ggtgccgggg gattcctcta cctcgtcgca gtgctcggcg tcacgggtgc cagggaacag
     7201 atcgatccgc gggtcatcgg gcacatccgg gcagtaaagg cagcatcagc ccttcctgtc
     7261 gtacccggat ttggcatcgg gacggcagga caggtccggg agctggtgcg tgccggcgcg
     7321 gacggggtga ttgtcgggtc cgccatcgtc cgggagatag aacgaaccct tgaggatccc
     7381 ttcgcgatga gagaagcggt gggagggaag gtcagggaaa tggcgtcagc cctcaggtga
     7441 ggtatcccgg cggacgggca gcctgccgac ggcagcacag tagatgacaa actcgtcgtc
     7501 accatcaaga ttaaggagcc cggccatcat ccggtcatcg aacgccccga tggcgcacgt
     7561 cccgcatcct atctggagtg ctgccaggta caggttctgg cagacgtgcc ctgcatcgag
     7621 gtgcacgaga cgccacgccc tctcagcgta acgccatgcc atacggtaga caacacagtc
     7681 ccagaggaaa gttactgctg agcttcggac gaatgcctgg ccaagacacg ctgccatcac
     7741 cctgtccgca gtttccggtc ccgtttggac ggggagaagc cggtgggaga atgcaaggta
     7801 ccggtatatg ccgggcttta ttcccctgac cctgttgacg aggagatacg tctcgaaggc
     7861 atgacgacct cctgccgagg gaacgttcct gagggtgtaa taggggtcaa cgacctggac
     7921 tatcccctgc gtgcaccaca gcaggtagga gagctcttcc tgcgtcaggg gatcccgttc
     7981 gtaatgccgg atggatcgcc tcgcctcgat tgcccggcgc aggtcgagtg gcgggacacg
     8041 gatggaacct ggaggaggca gcgggatgaa cgggccatca ggaggaaccg gtttttcgag
     8101 cggaggggcg ggaagtccac gggactggtc cgatggggag aggtactcgt accgggtcag
     8161 atccatgaaa tgcgggccga tggtcttcat ggttggaaga tacggttgga aagggataaa
     8221 ggcggcggca aaaggaagat gtgtccttga tcgggtttgg gttccaaggc accaggttca
     8281 taccgatcga tcgtgataga ttcatcacct cccccgtccc ggagaatatg aaacgaagga
     8341 attaaaatgg cgtccgcacc ccgcaaaccc ttttcgagga gaatccagaa tacgccccgt
     8401 tcgatgatca gggagatact cagggtcacg gagcggcctg atatcatatc ctttgccgga
     8461 ggactcccga gtcctgcatt tctcgatgct gccggagtgg cacgagccgc cggagaagtc
     8521 cttgctgaag acaattgcgc agcactccag tacgcgacct cggaaggttt ccctcccctc
     8581 cgggagtgga ttgcaaggag gtacaggacg cgctttggac tcgcagtcga tcccggggag
     8641 atactcatca cgaacgggtc acagcaggca ctggacatac tgggccggat ttttattgat
     8701 gagggagacc cggttgccat cgaggcaccg ggttacctgg gagctatcca ggctttttca
     8761 cagtatatgc ccgtattcca tccagtcccg cttggaacgg aaggaccaga ccccggggaa
     8821 ttttcacgga tagcgaggac agaagatccg gtcatgtact acgccatccc caattcgcag
     8881 aatccatcgg gtatcagtta ttccacacgc cggcgggagg aaatcgcaag tatcatttca
     8941 gattcggaaa cggtcctcgt tgaggatgat gcgtacgggg aaatacagtt cagcggggat
     9001 aagagaccct cgttttcccg tctcctcccc cgcgataagg tcatcctcct tggaacgttc
     9061 tcaaagatat tctcgccggg aatgaggctc ggatggctct gtgcggaagg ggaaatcctt
     9121 gatcatgcag tgacagcaaa gcaggcctcg gacctccatt cgaacatcct tgcacagaga
     9181 atactctacc ggtacctcca gtgcaacgac atcgacgccc atatttcccg cataaaaaag
     9241 gcatacgcag cccggtgcag cctgatgctc caccttatgg acgaactctt ccctggagaa
     9301 gtcacttata cgaggcccga cggcggcatg ttcgtgtggc tcaccctgcc gcatcccctc
     9361 tcggcaatgg atctttaccg gcgtgccctg gcagaaaacg tggcaatcct ccccgggacg
     9421 ccgttttata ccaacggagc gggagaccgg ggggtcaggc tgaacttctc gaatgcagat
     9481 gaggaaaaga tcaccgaggg gatgacccgc cttgccaggg tcctggatgc atacaccaga
     9541 gaatgccgga aaggacagag cagtccccat ccggaaacgt gatgaaagta aatcgtacca
     9601 tcagccccac catttgcgga atacggcgcc tgcggggaag aggcacagtg ccaggaggag
     9661 ggaaaccgtg gggaagggaa tctcggtggg tgccggtccg gatggatacg tggttatcgt
     9721 gggctgcgaa ggggaaggac cggtgggaga cagaggcccc gttgcccggc tgacctggaa
     9781 tacagaccct gtgacagcct cgcccccggc gttgagttct tcccattcga ggagaatgac
     9841 cttctcatcc gggaggtcgg gaggagtatc tccccggagc ccgattacaa gtcccacgtc
     9901 cctcgttgtg ggataggaga ggaggtaccc gttgaggaaa acccgcgccc cgtccttgcg
     9961 aatcacggca gcctgtttcc cgtcgactgt aacgatgatt tcccagcgtg cgttcgagag
    10021 gcctgatgaa aaagagagag tatgcgattc agagaaggtg cttgcaccgg acggaataat
    10081 ctcggcgagt gcagtcaggt tgaccggatc acctgccttg aggagatcac cggcgggttc
    10141 aacgcgcata tcgcgggcaa cgaccgctgc acctgcagga gatgacaggg caagcaggca
    10201 gagggatatg acgagtatgg cgggggagag tcgcatgaat gtctggtagg gaaaagggat
    10261 cagatatacc ctcctcattt ttcttccgga agaagccaga tctctccgat ggacatccgt
    10321 ttctgcgccc ggtacattgg agacggtcac ccgccgacga accggttctg ccggtcctgt
    10381 gactgccctg catgcgagga actgtggcag aaggtggtct ctcttgcgca ttcatgcagg
    10441 gatgatcccg tgcccctgcc acccacgcgg gcggtgctga tcccccatcc gtcgaacccg
    10501 gcgatggcaa ggatgcgggt caatgtcacg tggacgcttc ccaaggagga cttcctccat
    10561 ttcatctcga ccggcagggc aggcatggga aagaagggag accgggaaaa tccccggtca
    10621 tcgcccagca tgacgcgcca ggagccctat gtccgggcga tcgtggaggc actcggcgga
    10681 tgggatattc cggagatcgc cagggtcaaa aggatccaga agggggaata aaagaggtca
    10741 gcgcaggaat gtccggcgtg gaatcaccat atttaacgtc ctacgcataa aaaccccgga
    10801 acgctcccgg taactggcag gcaaatgcac tcatgccctg ccgggcgatg cgggtatcct
    10861 gacttgccag tgtgcaaaca ggaatatgaa gtcgaaaggg aagagatatt catggcgaaa
    10921 tggaataatg aaggtgaaag gggggggcat gcatgaacgt gaacctcttc cggggagata
    10981 gcgggtaagg gactgatacg gtgtgattct cactctcatg gccggtttct gccttgcgtg
    11041 tgccttcatc acgtttggtc tgggcgtgta cgttatcgcc aggaaccccg gatcgcttgt
    11101 aaaccgtctc tttctcctct cgatgctcct ggcagcttac tgggcactcg gggaattttt
    11161 gatctggcag gtaaggacgc ccgaaaatat cgggttttac ctgaaagcga gctcgttctg
    11221 gcccatggtc atcgcggtgt tcttccattt catcgtcgtc tattgcggcc atccgctttc
    11281 aaggaaggat aactcgtggg ctctcatcat gggtatctat gccccttcgc ttgctctctc
    11341 cctgattgga ctcctgactg acgacctgta tacggtcatc ttccgggagg gttacggata
    11401 tgtctacaca ccggtcattg gcagtaatgc aaatcttctc gaatcgagtt atatcctggc
    11461 tgtcatgctc ctctcgctct tcgtcgtttt catctcatgg aaatctgaaa cccggggaaa
    11521 agaagcctac cagaagcgcc tcgttggtct tggcgttctc actgtcattg catccggagc
    11581 tctgtcagcg ctcgttctcc cggctctggg aatatacacc ccgaacatgg tattcctcgg
    11641 gattgccgtt ttttcactcc tcatggcgta tgctatccac acgcagggcc tcttcgttgt
    11701 gacaccggag atggcaatgt cgcagatcat ggcattgatc ccggatgcaa tcgtcatcac
    11761 cgacgggaca gggaaaatta ccgatgccaa tgatgcagtg gcaggaatcc tcggcatacc
    11821 ccgggaggac gtttccgggc gggacattgg agaggttttc ggcggaaaaa gcagtggctc
    11881 cctgatggat acagtcctcc ggcggggccg ggtcaccgac atcgaggcag agatcgacgg
    11941 cggccagcac cgggtcgtca gcatttcagg tgccagagtg aacaatccgg aagggggccc
    12001 cgcgggtatc gtgctcgtga tcagggacat cacggggagg aaggccaggg agtcggctct
    12061 gcgtatcgcg aatgagaaga tatctctcct cacgcgcctg acccgccacg atatcagcaa
    12121 cctcgtgacg gccctctccg gctacctgga gctgatgcgg ggtgactgcg accggtacat
    12181 caaccctgca atccagaccg tccagagaat aacagaatac ctgcagttct ccaagcagta
    12241 ccaggacatt ggctcgaccc ggccggaatg gcaaccgctt gccgggatag tggcccgtgc
    12301 gatcggagag attcatgcgg agggtctgga gataacggtg gatgtccctg acgtggaaat
    12361 atttgctgat gccctcgtct accgcgttat ctatgcactg atcgacaaca caatccggca
    12421 ctcgggggga gcaacaaagg ttcgcataaa cacggaaaag ggggaagaca acgcactgac
    12481 cgtcgtcttc gaggacaacg gaagggggat aggggaaaaa gacaaggaac tcatcttcca
    12541 gtacggatat ggaagtcaca cgggactcgg gcttgccata tcgcgtgaca tactcgccct
    12601 gaccgggctg gacgtgaaag agacgggtgt ccccgggaag ggtgcacggt tcgagatact
    12661 cgtcccagcg ggggcatgga aagagaggtg agtcactctt cccgcacgac gtaatcgtcc
    12721 tcgtctccga aggaaaagag ggtatcaatt gtcgtcccca gctccttcgc cacgcggtgg
    12781 gcaagccgga gggaagggtt gtaccggcct gcttcgagga agactatcgt ctccctcctg
    12841 acaccgaccc gatcggcaag ctctgcctgg gtcatgtttc tctttgtccg gaactcgcgt
    12901 atccttgtct gcatggttcc tccaccgtca ggttacctta atccacgtct cccctgcgga
    12961 acaggtaaat ctggaacgca cgtgccgaga tgcccatgag caggataagc agtacggaca
    13021 gtgttgcggc atccggcgac cagaccccca ggtaatccgc ccagaaaacg acaaagagta
    13081 cgatgaaggt gagaaaccag gaccaggaga gaccgtacgc tcctatcttt ctcgttctct
    13141 cgtcctggag ggagtcccct tccccccgcc agagcttcag gccggagagc acgatgagca
    13201 ccgcacccat ggagatgaaa gcactggaga acgtcccccc cgctggaggt gagaggagag
    13261 acatcccgac aatgcctgca gagagcatga acaggccggc gagaaacatc cagacaagcc
    13321 aggtgcgggt tttgaacaga ccgcggttat ctttcttcat tgcaaccatt tctgttaatt
    13381 atttttaaca catgttatat ttataacaca cgcacgtccc cctctctatc atgccacgcc
    13441 cggaatcgaa cggtggcagg gggttgggca cagcccgtga ccggttcaga acgaggcagg
    13501 gaatcacccc atggtgcagg aaaaaactaa ttcatgccgt gaccatctct gcctcaatgc
    13561 cgggagacat ctgcttcaac aggttctgga gtgctatcct cctcaaaaat tccacgccgc
    13621 gccggtgcga taacagggta aagaaggtat gcagggagta ttacgtcatc agtcccgggg
    13681 cactcttcag gggtgtgccc atccagatac ctgccccgat gctggtagga atcgacgagg
    13741 agaacaagcg tttgctggtt cctttcagga aaccctgtta cgggctctcc ctctacgtca
    13801 tcgagtctga cagcagggag atcgaggaga tacgaaaaga gctggcaggt atggaacccc
    13861 acatccctgt cgcgacacga ccatcgaaat agggtctttg ttcatttaaa cgggggggtg
    13921 ggagaggaac gggagagctg ccccgccccg cagtccagag agtgaatagc gaaacgggtc
    13981 agattgactt ttcccatccc tggcccatgt cgacgagggg ccttacttca acgacccgga
    14041 acgttactgc cgcggccatc attgcggcgg catcctttcc cgcaaccttc gcgatctggt
    14101 ctttgagtcc ctccagtgca ggtccgtgcc gggcaatctc ttttgcctca aggtagaccc
    14161 tgaccccctt ccagtccatg atcgattttc ccggctccac gatcatgtac acagcgtgcg
    14221 ggttttcgga aagacaggca agcgtcctgt tcttcgcaag gccgatgacg acagtctttt
    14281 catcagtcat atgtgcagag ccaatcacgg ccacgtcaac cctgccgtcc ctgccggacg
    14341 tcgcaagaat tcccaggcgc ggctgtttgt tgaagtattc gacgagcttc gatgtcatat
    14401 gtaagtccac cttctaccgg gagtatgcct ctctcccccg atacgaaaaa atgttacgtt
    14461 tccacccctt ctcctgcatg ctctccaggc aatctctccc ctcaggatag tatcatatgg
    14521 tgcagaacaa ccaacagttt catgatagag acagatgatt gaccggttgt tcaggagata
    14581 ccccctctct acctaccttg cccttgcaat cttctgcatt cttgtctttg cggttgccgg
    14641 gcttgttgct atcagttatg tctccatgga aagaaccctc tctgacaacg cccgatccgt
    14701 gcagcaacag accgagaaca accttgtcgc agtcctgaaa acgaaggaag aagggctccg
    14761 gctctttgaa gagagcctga acagggagat ggaggctgcc ttcgtcccgt tccttgcgga
    14821 atacgagagg gctggagggg atcccggccg catggatctt ccagcggtaa aacgtgagat
    14881 cgggggtgac atggagcttt atgtcatcga tgccaacgcg acgattgttg cgacaaccta
    14941 ttcccctgaa ctcgggctcc gtttcggcga ttatgcaccc tacttcgtcg ggtacctgaa
    15001 tggcatccgc ctctcggatg gttttttccc tgaccgaatc gtgagtgaaa aatcgaccgg
    15061 tgcgctgaag aagtatgcat acaggaccac accggaccat gcatatatcc tggaactcgg
    15121 ccttcccgtc acgatgccgg aggtcccgac gttccggtac cccgacaggg acctcatcat
    15181 ggaggtcgaa aaggcaaatc cctacctctc gggcgtgagg atctttgaca cgaccctgcg
    15241 ggaaaggatt gacgatacct cggtcgaagt tactgacccg gtactgaagg aaacgttggg
    15301 gcatatcctt gcgacccgga gcagcatgga tgcggctggt gggaaaccgg gaatcctgac
    15361 gcggtacctg ttcgttgact taagggacaa taaaagcggc tcagacgtca gccggatcat
    15421 cgagctgaat tatacgatgc tccccgttac gaaagcattg gagcgggcac tcgtattcca
    15481 tatccttatc ggtgtcatat ttctctcggg atgcgctctc gtggcatttc tcaccatcag
    15541 gaagtttacc cgtcccatcg agacaatggt gggagacctc gaccagatta cccgcgggga
    15601 ccttgaccat cccatctcac caccgctggg aaaagacctc ctccggctgc aggagagcat
    15661 ctcacggatg gtggtgcagc tcaaaaagac cctcgaagcc gtccggaaga gcgaggagga
    15721 cttcaggacg cttgtacagg gtgcaaacag catcatcatg cggtgcgcac cggacggaaa
    15781 aatactctac atgaacccat ttggcttcgg ctttttcggg tacgcggaaa aagaaatcgt
    15841 cggaaaaagg atccacgaga cggtgtttcc ccctccggca gggcagggag acgttgcaga
    15901 aagcccggcg caggaatatc acccgttctt ttccctttcg gagtgtaaga tgcacacaaa
    15961 aaacggccag gacgtatggg tggcctggac gcacaagccc ctttatggca gggaggatac
    16021 accatccgag atcctctcca tcggcaatga catctcccgt ctcaagcagg cagaacggga
    16081 gatccaggag ctgaacgccc ggcttgagca gaagatagtt gagcggacgc gccagatcgt
    16141 cgaggcaaac aggaacctcg aggccttcac ctactcggtc tcccatgacc tgcgagcacc
    16201 cctccgtgcc atttcggggt attcgtccat cctcctctcc gcgttaagtg atctcccgtc
    16261 ccgggagagg aggtacctgg agcagataca gcgcagctcg cacaagatgg gggagctcat
    16321 cgatgacctc ctcactttct cacggctcgg cgggcaggcc ctgaaaaaaa agacgctcaa
    16381 ccctgccgat gttgttgaag aggtactcct ggatttccgc ggggagatac agaaacgcaa
    16441 tattgaagtg agggtcctgg acatgccgcc atgcagcgca gacagggccc ttctccggca
    16501 ggtctattac aacctcgttg caaatgcgat aaagttctcc cggtcacgcg aaaggccgat
    16561 cgtcgaaatc ggggcccggt tccatgaagg gttgcctgcc tattacgtca gggacaacgg
    16621 gatcgggttt gacatgcggt actccgcaaa acttttcggg gtcttcgaga ggctctgtga
    16681 caccggggag tacgagggga cgggggttgg ccttgcaatc gtgaaacgga tcatcgaaat
    16741 gcacgggggg agggtctggg ccgagtcaga acctgacaag ggagcgacat tcttcttcac
    16801 gctcggggga gaaacgggag aaaagaagga ataaccctgc ctttttctct gcctttttcc
    16861 ggtggcccac cttgccttgg atctccttaa tctttcttcc tcctggtttt caggacgaag
    16921 atccccaaaa atcctgataa gcagacggtg gcgaggagag aaaacgtccc gggacctgtg
    16981 ctccgcgtgg gagtctgtgt ggggaggggc tggagggttg caaaaattcg gatatcctgc
    17041 ccggccatca cgtttccgga cgttgagaac ggggaatacc catccagccg gacttccacg
    17101 gtgtaattcc cgggagagac gtcattgacc gagagcggcg tcactccggc atacgcagaa
    17161 ttgatgaaga catcggcgcc ggcaggggtg gaggttatct ctgcgctcgc gattcccttg
    17221 ttgcttccgg caagtggcgc cattacctgc agaaccccgc cgggctcgac agacactgtc
    17281 gtttgaaagt ccaggtatcc cggtttcctg acgaccagcg tgtactgccc gggagagaga
    17341 tcattgatat cgaggaggtc atcaggagtc gtggaacccc tgtagtctcc gttgatgaag
    17401 actgctgcac cgggtggcgc cgatgcgacg aggatatcac ctgtcggggg gctgatttcc
    17461 gggtcgagcc ttgcagagac aggggtgatc gtccctcctg ttacagttac cgacttttcc
    17521 cacgccagat agcccgcttc ggttatcctg accgtgtgcg ctcccggtgc gagatttccg
    17581 accacctggt ccgtctttcc catgtacctg tcatcgacat agagtgatgc gccacgcgga
    17641 tccgaactga tcgagaggcc gcccgggttt gaaaccgggt cgagggtaac gatgacattc
    17701 tcggttgacc cggccgtgac cttcacgttc gcatacctgg gaaaaaagcc ctgccgggag
    17761 atctttacga cgtgcatgcc gggctcgacg ccggtaaatg tccccggcgt caagagggat
    17821 cccgcacccc cgtcgaggat ggcagatgca ccggccggcg tcgaagcaac gtatatgctg
    17881 cctgtctggg agaacccttt tccggtctcg atcgatgcct ggatagtcat ttcagccatt
    17941 gcagtactgg agatcagcgc cgccaggaca accattgcaa gaagaatcct ctgtgtgaac
    18001 atgtcctttt gctccgtgca ggaatctccc ggcatgtata aaaaaccctg cgtgggatgc
    18061 agcccaggaa aaaggggatg ggacttttcc tcaatacccg cttgcgtagt agtacccgtt
    18121 ctcctgcctg accgtgacgg gtacaccgaa gagatcctga aggttcctgt cggtcaggac
    18181 atcctctttc ctgccgtcca tcctgattcg accatccttc atgaggatga cgcgggatat
    18241 ctcggggatg atgtcgtgga gggagtgggt gaccatgatg atcccgacac ccgaccgggc
    18301 gatgtcacgg atcactttcc tgaatgcgtg gagtgcggcg aggtcgaggc tgttcgtggg
    18361 ctcgtcgagg atgagtgtgc ggggaccgtg gacgagtgcc cttgctatca ggaaccgccg
    18421 ggcttccccg gttgacaggg tgtccatcgg tcgcccggcg agccgatcga tcccaaggaa
    18481 gcgcatggta ttctccgccc gttcttccat ctccggggtc acatggtggt ggaagaggcc
    18541 gatgctcgag aagaagcccg atatgactac gtcacggccg cagacgcccc gcgtatactg
    18601 catctggagg tctggagaga ccacaccgag ggatgaccgg agggcaaaaa catcccagac
    18661 ctcgcgtccc tggaagcgga agatgacgtc gccggcccca tccaggacag ggtagagctc
    18721 ccgcgtgatt gtcttgacca gcgtcgactt tccggaacca ttcggaccga gaatggcgac
    18781 atgttccccc tcgcggatcg cgaggctgac ccgggaaagc accggcgcgt ttccccgcat
    18841 gactgttacg ttggcacatt cgaggaggaa tggacgggaa ggcgtactgt tccggttcgt
    18901 ggtcgctcac cttttatgcg aagtttggta ccggggatcg ggtacgtctg ccccggcgga
    18961 aggtgatgaa ttattctctt tccctgcaca tgagggtagt ggctgtccct ttatgcggaa
    19021 tctgcttaac cggtccgttt cccggcagac agataaatag cccctgcagc gaaacgatcc
    19081 tgtcgatgga tcaaaaagtc cccggaaccg aactggcaga ccggatgcgc aggttccgcg
    19141 agcggatgga ccggatgcag cctgactggg aaatggccgt ctttttcgga aagatcaacc
    19201 tgtattacct gacgggaacg attcaggacg ggatgctcat tgtacccagg gacggccccg
    19261 aggagttctg ggtgagaagg agttttgcgc gcgcatgtat cgagtcggac tttcccgtta
    19321 tcaggcagat ggcatcattc cgcgatgcag ggaaaggcat cgcccgtgtg cctgaaacgg
    19381 tccacatcga gacgggaatc gttcctgtcg gtctctggga acttttcagg aaacattttc
    19441 ctgtccgcgc cgcgggaagc cttgacgccg aggtggcaat gacaagggcg aaaaagagcc
    19501 cctatgaaat cgccctcctc cgaagggccg gagagatcca caggaccgtc ctcgaagacg
    19561 atgtccccgg catcctgcgg gaggggatga gtgaagccgc gtttgcatcc gctgtctacg
    19621 aacgcatggt ctccctcggc caccagggga ttgtccgttt cggcagtttc aataccgaga
    19681 tcgaggtggg tcaggtggca ttcggggaga attccctgta tcctacgtat ttcaacgggc
    19741 ccggcggttg ccgcgggatg gggccggcgg cacccgttct cggagacccg gaacggacac
    19801 tgaaacgggg ggatctcgtc ttcattgaca atgcctgcat ggtgggcggc taccagacgg
    19861 acaagaccat gaactacgtc ttttgtggca gcattccccg ggaggctgaa gagatgcatg
    19921 acaggtgcgt tgctctcatg gaggagatgg catcgatgct cgtcccgggg gctgtcccct
    19981 cgacgatcta cgcatccatc atggggagcc aggatcctgg ttttctcgaa catttcatgg
    20041 gacatgccga accgaaggtc cggttcctgg gtcacggcgt cggtctcgtg gtcgacgaac
    20101 cacccgttat cgccatgggt tttgatgaac cgctcgaaga ggggatggcg attgctctcg
    20161 aaccaaaata cgcggttccg ggcctcgggc tggtcggaat agagaacacg tacctcgtca
    20221 catgccgcgg cggagagagc atcacaggca gtcatcccgg gctgatcccc gtttcctgac
    20281 gccctcctcc attccttccg cggattcccg gtaacccctg ctcccgttcc ggtaccgttc
    20341 aaaccagtaa tttttatata acaatatgta aaacatattt gacacatgtg cgggaaacgg
    20401 aaaacccggg aggaataaac aggatgatat ttcaggatat gactggcatc cgccgttcca
    20461 gatgcctgct cgtggcgatg atccttttac tcattgcagg agctgcggct gcagcaacga
    20521 cggcagagaa ggcagcatcg tacgtggggg tgacatctgt ctcgatcgaa cccggtgtcc
    20581 tgatgcagga cgatacgggg acgatagtca ttgaaataaa gaacagcggt tcggaccctg
    20641 tatcgattgc ccgggcagag atcctctcca gtgatattga agtactcaat taccagacat
    20701 acgactcggt cggggcaatc ggtcccggaa acacgatgaa attcacgttc cacgtccggg
    20761 ccggcgtcag ggacggagtc tatttcccga tgttctacct ggatttcacg gatgcgggga
    20821 gtctccgtta cccgatagca ctcgaagtcg agtcttcacc cgtatctgtc agcgtgatcg
    20881 atgcaccggg ttccttttca cccgggacaa agaacaaggt cgtattatcc gtgaacaacc
    20941 cacggaaaaa taccgtcaac agcgtgaccg tgacgccggg cggagacggc atcaggacca
    21001 cgcaggggag tgtcttcatc gggacgctcg ccgctgacga ggcaaaaagc gtgaccttcg
    21061 aggtctgggc cgagaaggag acggcacttg catttgatgt atcgtaccgg aacggtctca
    21121 acacccacca ttccgtcatc accatcccgg ttaccatcgg gggccgggag actgcagcag
    21181 aactcgttgt gaacaacgtg gaggtgaccc ggaatggcct cctggtcacg atcggtggtg
    21241 atgtgacaaa cgcgggcctc gaagacgcca aggcagtcaa ggtgacagtc gggagccctg
    21301 caacccccac tgacccaaac cccgtatacg tgatcggatc gctcgagccg gatgacttct
    21361 ccagtttcga ggtgacctgc acggtgcggg gagatgattc cgtgcccctg gtcatccagt
    21421 accgcgatac cgagggaaat ttgtttgaaa aaacgatacc cgtttcgatc cgggcgggtg
    21481 ctggggggtc atcgggaacc ggaaacccgg caggaatcac ccagggttca tccccggtcc
    21541 agctcaggcc ggggggggtt attcgggttt ggcaacggtg tcgggaaaat acccgtgacc
    21601 gagattgcgg tcatcatcgt tgtcgcggtc ctggtcatcg ttgcatggcg gaagggatac
    21661 ctggcatccg tggcagagat tatccggaag cgcaggcagg gatgaaggac cgtgccggga
    21721 gattcgatca ttgagttgtg cggggtgaca aagatctatt ccctgccggc tggggacgtc
    21781 gttgccctgg accgcgtctc gttgacgatc gaaaacggcg agttcgttgc aatcatgggg
    21841 ccctccggtt cgggaaagac gacgctttta aaccagctcg ggtgcctcga tcggccgacc
    21901 tcgggggatc tcttcatcaa cggcaggaac acgagggaga tgaacgacag ggagctgaca
    21961 agcctccggt tgaacacgat aggttacatc ttccagcgtt tcaacctcat cccgctcctt
    22021 tcggcatacg agaacgtcga gttcccctac ctgatgaagc acaggagacc ggattcttcg
    22081 ggtcgcgttg gagaactcct cgcgcaggtg gggatcgaca gggctatggc aacccataag
    22141 ccgccggaac tatccggggg ccagcaacag agggtggcta ttgcccgcgc cctcgtcaac
    22201 gatccgcaca ttctcctctg cgacgagccg accggaaatc tcgactcggt cacggggcag
    22261 cagatcatgg agatgctgac cgacctcaac aggaagggga ggacgatcgt catcgtcacg
    22321 cacgatccgg gagtcgcccg gtatgcgcag cggatcgtca cggtccgtga cgggagggtg
    22381 gcatgaagga tatcatcctg cagctcgccc tccggagcat acggatccat ttcctccgct
    22441 ccgtgcttgc agcgctcggt atcgtgatcg gggtcgttgc catctcctcc atggggatga
    22501 tgggtgcaaa catgacactc tcggtgaccg aggaactctc caagatggcc aacatcgttg
    22561 tcatcacggc agcgtccgga tccgaaagag ggcccggcgg nnnnnnnnnn nnnnnnnnnn
    22621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22681 nnnnnnnnnn nnnnnnnnnn tggccaacat cgttgtcatc acggcagcgt ccggatccga
    22741 aagagggccc ggcggctttg gcggcgggag cgacgagaag atatcagagg aggatttcca
    22801 ggatatccag aagattgcag aaaagtacgg cctcgtgtat gtggtttacc gggaatcgga
    22861 tcgcatcaag gtcggagaca gggagggacg gtccactatt tacggcctcg acgaggacgt
    22921 catgcgccgc atattcacac tgtctgatgg tgcatttccg aaaagcacca gttccgtgat
    22981 cgtcgggcca acccttgccg ggcggtacga tctgaaagtc gggagccgga tcaggatcgg
    23041 ggacgaggac aagggggcta ccactacggt gaaggttgtc ggcatcctcg aggagagggg
    23101 catgtcaaac gacatcaact ccgatatggc gatcatcggc agcgagaagc ttttcacggg
    23161 gatatacggg aacgaggggg agtacaatca ggttaacctc atcctcaacg atatcaacga
    23221 ctcccagaaa gccaggaccg agatcctcga gaagatgaac aggaaaaaga cgagagtaaa
    23281 cgtccaggac agcagccgga tgcttgagag catcacgtcg acgctgggga cgatgacaac
    23341 cttcgtgatg gcaattgcgg ggatctccct tctcgttgcc gccacctcga tctttaacgt
    23401 gatgatgatg tctgtgaccg agcgggtcag ggagatcggt atcatgcgga gcatcggggc
    23461 ccagaaatct gagatacggc ggatgttcct ctacgagagc gtcgttctcg gtctcgtcgg
    23521 ggcaggtata ggggcggtcc tagccctcgg gataggctgg gtcgttgtcc tcgcgatggt
    23581 gggaagtaca gactactttt tcctgcccga aagcctcgta tatatcccct tcgccatgct
    23641 ggtcggcatc gcggtatgca tcctgtcggg cgtctatccg gcgtggaggg cagcagatct
    23701 cgacccggtc gaagcattga gggcggaatg aattgaatgg tgactcaagg atgggaatca
    23761 aagaaagtgc ccgggatgag aaaatggtca tcatcgcatc gttgtgcatc gggatttgca
    23821 ctcctttcgg atggtgcaac aggggaaaaa gaggtaacag gaagttccgt gaccacgcaa
    23881 ccatcacccg accgctgaca cagggatgca ctgtccccgg cactcaacgg gatgccgatg
    23941 gacaatcccc cgggcacacc gcccgcttta tggaacatga caaaaggaca gtgaccggag
    24001 ggcaacgttc cgggccaccc ggagggatga acatgccatc cccggaaccc ggacgggaac
    24061 ctggcagaat ggtcaccccg gcaaccgtgg atctgaaaac gatttccgaa tgacaccagt
    24121 gcagggtaga cccgtttcct ccctattcgg ttgccaaagc gatgacgaat agagatcgta
    24181 tcccgctgat acctttgttc cccgcaaaaa ctaaagccaa tccggagtga tactctctca
    24241 acgtagctct tctggaggtc accccgtgga atttatccca gcagtgtctg tcctcatcct
    24301 gatatccatc gtcttcatct tcatcgcaca gaaattccgg ttaccgagtg tcgtcagctt
    24361 cctcgtcatc gggatgctgg tcgggccgtt tggccttgcg attatcagtg atcaggaggt
    24421 gatctcatcc ttcggggaga tcgggatcat tctcctcctc ttcacgatcg gtcttgaact
    24481 ctcctttgag gacatcgccc ggttctggaa ggtcatcttc gtcggcggct tcatgcaggt
    24541 ctgcacaacg atcatcgtta tcacctcgat cacggcagtc ctcggttttc ccttcaacga
    24601 ggcagtgttt tttggcttcc tcgtctccct ctcgagtacg gccatcgtca tgagggtcct
    24661 gcaggaaagg gggtccgtcg agacactcga gggaacaacg ctccttggca tcctgatatt
    24721 ccaggatctg gcaatcatac cgatgatcct tatcaccccg ctcctgatag ggcagaccgg
    24781 accttcctac gagcaacttc ccctcggcat tgcaaaagtc atcctgatca tcaccctgat
    24841 catcgtcgcg tcgatatggc tcattcctgc actgctcgac cgcgtatcga gggagaggaa
    24901 ccgcgaactc ttcctcttaa ccatcgccgg gatatgcttt accgtcgcgt acctcacgaa
    24961 tgcggccgga ctctcgctct cgctcggggc attcatcgca ggactcgtca tcggggagtc
    25021 cgagtattcc gtcgatgccc tgagcgacat cctcccgttc cgcgaccttt ttgccggtat
    25081 cttcttcctc tccatcggga tgctcctcga cacgagggtg gtcctcacgt acttccccat
    25141 cgtcattttg gttatcgtca cgatcctcgg ggtcaagttc ctgaccgggt ggctgtccgt
    25201 ggcatcgatg ggactgcccc cgcgggtcgc aatccttgca ggtttttcac tctgccagat
    25261 aggcgagttc tccttcgtcc tcgccagttc gggactgcaa tcacaactca tctcgatcgc
    25321 gacctaccag atattcctct cgggcgcaat cgtgacgatg gctgcaaccc ccttcctcat
    25381 gggagccgcg caaccggtta cagacctcat ttaccgcagg gtacccgtcc gggttaagga
    25441 cagggaaaaa ccgggggaag aattaaagcg ggaagtatcc gggcacgtcg tcattgcagg
    25501 gttcgggaca gcgggcgcag ccgttgcgag ggcagccgag atagccggga tgcagtgcca
    25561 tgtcatcgac ctcgatcccg atgccgcacg gagggagaag gaaaaaggaa ttctcttcac
    25621 cataggggat gcaaagaagg acgaaatcct cacccatgcg ggcatcgggc gtgccgccat
    25681 cctcttcgtg acggtcctcc cggcaaagca ggcagagatc atcgtcagga gagcacggcg
    25741 gctcgccccc gggcttccca ttgttgccct gggcggatca cccggtgaca ttcccgttct
    25801 cttttcagcg ggtgccgacg aggtaatttc catcgagtac gagggggctc tccggctgtt
    25861 tgcacgggca cttgcacgct tcggcctttc cgaagacgag gtcgaccctc tcctctcccg
    25921 catccgtgcc catacctacc ggggtatcac accacggtca tcggaaggcc ttccgcttgg
    25981 aaagatcgaa agaaggctcg aagaacacca cattttcagt gtcccggccg ggaagggaac
    26041 gcagatggcg ggaaagactg tcggcgagct cgatgagctc ctgccaccag acgtttcact
    26101 tgtcgccatc aggcggggag gcaggactct tgcagaagtg acaggggatt tcgtgcttga
    26161 ggaaggagat actctcctct tttccgggcc gccgggcagg gccggagagg tcgcatttct
    26221 cgtgtcagga gaataacgag gaggtttccc gcggaggtat aaaatcagtc agtcttccgg
    26281 caggcagcac cctcccctat tttcatcctc actttctccc agctccctgt agtcaggaag
    26341 ctctcctcca ttgcatccac gatgcgggaa aagaggttca tgggaaaggc catcgtgagc
    26401 gtgtcgtgcg gaacgcaggg gcgggccgag ggatcgaaca ttccgaggac agcccggggc
    26461 ctctcttcct ttgcctcgag caggggatag tggatgatcg agctgcaccc cgacccgaag
    26521 ggacaggtga cgccgcaggg gtccggtctc tcgaagtttg cgagggtaaa gaggcctgaa
    26581 aggacttcac cgcgtgcgaa gaagaccacg acatccgggc agtccgcgtc cgagagggtg
    26641 tcccacctcc ggaagagata cttccggctc cctgcaggaa gaaaggtgct acgggcagtc
    26701 agtgcatcaa cgagttccgg agacttcttg tacctctccc ccctgacaga acccggcttc
    26761 ccggtcgaga ggaagtaccg gaagtcaggg ctcctttcct caacataacc catgtaatac
    26821 tgtgcgccgc tgcaggagag ggagccggaa ccgaggagaa ggctccgtcc ttttctgacg
    26881 cgggagaggt cgcagacgac gcaccgccat ttccccggcg gctttgcctc gggaagtccg
    26941 gagtcccgcc cggaaagctc aaacgttatc ggcagctcgc aggaggggaa gtacctgtcc
    27001 cacagtgcaa tgaacctgtc acgcagttcc gtgtccatgg gagccggttc cccggtcgga
    27061 acataaaagt atccgggaaa gtccccggga tctctcctat aggttcagtg attggcaggg
    27121 ggattttcag gggcgggatg tgccaggtcc ctcacgatgc ggcagtcggg gcactcctcg
    27181 cactcgaact cgagcgtcga atggtgtatg ttgtaccggg caagccgatc cctgatctcg
    27241 gatcgtatcg aggcgatgcg gcgggggtct tcctcgcagc tgtacacgtg ggcatcgagg
    27301 acattgatgt gggaacagag ggtccagagg tggatattat gcaccccttc gactccctcg
    27361 acgttcagga tgtcctgcac catctgctcg aaatccacgt cccggggggc gaactggagg
    27421 agtatcacca tgcagtcccg gaccatgagg agggacgtgg cgaggatgac gatgacgatg
    27481 gcaagggaga tgagggggtc ggccaggacc tgaccggtca gggctatcca ggcggctgcc
    27541 ccgacaacgc caatcgacga gagggtatcc ccgaggacgt ggatgaacgc gctccggatg
    27601 ttgaggtcgg gactcccgtg gagcagccag acgaggaaga tgttgacgga gaggccggca
    27661 agccccacga caagcatccc ggtggaataa accggggctg ggctgaacaa tctcccgaca
    27721 gcttcctgcg cgatcaggaa acagagcccg atgaggacga gaccgttgac gagggccacc
    27781 atcacctcga tgcggtggta cccgaacgtg cggctcctgg taggcaggga ccgtgcaacc
    27841 acgacagcac cgagggagag gagaagggca gagccatcga ccagcatgtg cccggcatcg
    27901 ctgatcaggg caagcgaccc ggtcaggaac cctccggcaa gttccactcc gaaaaatacg
    27961 aacgtgacaa ggaccgcaat cttcagcgac ttctcgtgct ggtggacgtg catgatagaa
    28021 ccctgtggca gatacagcgg cggacggggg gagagtcatc cattcccatg gtcatgggaa
    28081 catgccaccc ccctgcatct ttccggagcc tattttcccg ggtctatcca gcccatccgg
    28141 acataccagt cgtactcgtg gggccacctg tccttgttcc agaggaccag ctggcggaag
    28201 tagtcccgcc tctggcggag catctcctcc tggtcaggat acgtgtactt cccgcgaatc
    28261 gccccgacaa gcgtctttcc aaggtcccgg gcatcctttt ccgctctccc gagtgcggac
    28321 gggtcggatg caaccgcaac accgactcct cccacggcaa cagccccgag tgcgttgagg
    28381 acgtgattga ggtattccac gatcctgtcc tggttgcttc cccctgccgt gcagaccgag
    28441 cacccgaact tgcctgtgaa catcctgcag tggatggcat cggccatcct gtcgaatacg
    28501 gccttcatcg gtgccgggat ggaatccacg tagttggggg ccccgagcac taacccgtcc
    28561 gcccccatca tcctctcgaa gagttcgggg aaatcgtccg tcagggtgca ctcgcccgtg
    28621 gcatagcagg tcccgcaggc attgcagtat ccaatctcaa gcgcgtaaat gtccacgagg
    28681 tctgtctttg ccccttcatc acgggcaccc tgcaacacag cctctacaag gcggcgcgtg
    28741 ttgctctcct ttccccgcgg gcttgcaata agcccgagga ccgtcggggc ctttcctgtc
    28801 tgcgtcatac tgagtgggat cagggattaa cgaggataaa actgccggtg ggtggaggag
    28861 aggagccgtc tcgccaaaaa aaggataatt gatccctgaa atgagccggc ccctacctga
    28921 agaaaaggac tctcttgacg tcgtctaccg tcatcccgtt gtccatcccg aggccgtaca
    28981 tgacctggac cgccttttcg tcaaggaagg acagtgatgt tgcattgttc tccgggaagg
    29041 caaagatgct gtccctgtac cggagggagt ctcccttgaa cccgagggtg tagaggaggg
    29101 cacgcaggag gtagtgggtc ctcatgtccc cctccatctg gtcgttgatg tagatatcgt
    29161 atcccctgat ctttgcacag gtcatcccgt cgcaggagaa ctccctgttc agccagccca
    29221 cctccgatga aaggtcgact gccttcaacc cgtccggcgg gaggaacttt atccgtatgt
    29281 caccggactg gcccgtcttt gtattttcga agagcttgtt tgactgggac agagcattga
    29341 acttcaggat aaaggcctct atcgtctccc tgtcagagtc acgtcctgca ttcagggata
    29401 tggtcgtccg ccgggtggag agcggaagcc gttcgaggaa gatattcccg ctcccgaacg
    29461 ccacgtcgat gaagtggagg ttgatgtcct cgctcgagag cagcgtgggc gcgggagtga
    29521 aagccgggat gacaggtgtc tctgtctccg tgaccaccgt ccccggggga ggaggcaggg
    29581 tgggaagggt ggttgtctcc gatactgccg tcggcgggga gggggagagg catcccgcca
    29641 cggcaaggaa cgcaagagtg aaaatggcca gaaatggaaa aaataaccgg ctattcatga
    29701 atattgttcc ctgcggaaag aaaataatgg ttatgatgaa gagttgcgga agaggagagg
    29761 ctggtcatgc cgcagggctg gaggtggccg gattccgggg cccgttaacc atggtaacca
    29821 tgatcactgg tatatgcaat gaaaaccaat aggtatccca cggggatgag ccaattgttc
    29881 ccagtggagt tgctgactta ttagtaatca tacaagaacc gacagggaag aggagatcgt
    29941 ttttgaccag tcgaccccgg aaggtatgga aacaatccgg gtacgcctcc cgaagaaacg
    30001 gaacagggaa cagtttgcaa tcgccgaact gatgcttggg tcaaaccata tccgggtgag
    30061 gtgcattgac ggggttaccc ggatgggacg gatcaagggc aagatcaaga agagggcctg
    30121 gatcagggag ggagataccc tgatcattac tccctggagt ttccaggacg aaaagtgcga
    30181 tatctcctac cggtatacac ggccgcaggt ggactggctg cgcagaaacc ggtatctctg
    30241 atatttttta ggataactca gttttttcct gtgtctccgc agggagacgg ggggtttcct
    30301 gtctttttgc gtggtgacac tttttttggc tggcgcaccg gatgggagga atcgtgacca
    30361 atacgaaaat tccggcccgt tttgtgcaat cggggattct ccctcccttt cccgggaaga
    30421 tacatcatac acatttttcc ggacaggccc gtcacttatc cggtgttcct gcatgtccgg
    30481 aaattatcct gcggagtggc cctgacacga tgaggagaac cgggatgagg gcgtagcacc
    30541 acatgctccc tgccgggtcc aggaacgata caccgatcgc aagaaggatg acgagcggac
    30601 tgataacggt tctcgccttt ccctctccat tgccccctgc agcacccggt gcgagctcat
    30661 cccgctttct cgcgatgtaa accgtcattc ccgccaggag caggctcgat gcaaggaggt
    30721 tgacgtggaa gaggagaacc gcctcgggga catctgtgta atccccggat agggaagtcg
    30781 taaaggggat gaggacgatg gaaaaaagga ggaagatgtt gatccgtaca agcatgccgt
    30841 caacgtaacg gattttaccg aggatacggt ggtgggagat ccagtatcct gagagtacga
    30901 agaacgcaat cacgaagagc atgaactcgg gaagcaaccc tgcgatcttc ccggggagga
    30961 ggaagggagc ctggtcacgg ggaatctcgg ggacggtgag ggagaggacg agcagcgtca
    31021 ttgcaaaggc aaagataccg tcactcagtg cttcgatccg ggactttccg atcctctcca
    31081 cgaacagcgt ctcccgattt ttagaggaga tttggcgggt atcagataaa aatggcactc
    31141 cctgccggga agaggggaaa aaggctgggg ccggggaggg ttccccgtca gcgctgtacg
    31201 gctgtcacgc gcggcggctt catcaggacc agtgcaaggg tgaacccgag caatgccagg
    31261 acgaggacgt aggggaatac ccccatgtag gttccggtcg ttgtcttgat gaaccctgcc
    31321 agctggggac ccgcgatcgc tccagccccg taggcaagga agacgatccc gtagcagcgg
    31381 ggataatcgc acgtcccgaa atacgaggca gttgccgtcg gagcgatggc gagccagccg
    31441 ccgaggcatc cccagaggat agcaaaaccg gcgacgtaga ccgggacgga cggcgcctgc
    31501 cagagagcaa cagatacggc tgcaatgagc acaaaggaga caagtgccgt gttccggggc
    31561 gtgatcctgt cggtgagtgc gccgaagaga ggcctgccac ccccgttgaa gattgcaaag
    31621 aacccgacga ggagcgttgc aagccctgtc tcaatcccga tctccgtccc gacgggcttg
    31681 gcaatcgaga tcgccatcag tcctgccagg cacccgatga agtaacagga ccagaggcca
    31741 tagaacgccg gtgtcctgac catggcagca cggtcacatt cgcagatctc ttccccgggt
    31801 tttaccggcg ggggtgtcca gcctgccggt ttccaccccg ggcggggaaa ccgcagcggg
    31861 agagcgagga gcacgatcag gacgatgaac gcgattccaa agacccggaa cgtgttcatc
    31921 acacccgcag cctcgatcag gtatcccgcg atatttgcgg tgaggaatgc cgagaacccg
    31981 aaaccgagga gtgtcaggcc tacagccgtc cccctcctgt ccgggaacca ccgggctgcc
    32041 acggcaacag gcacaccgta cgcgattccg acaccgaccc cgccgatgat accgtacacg
    32101 atgtagagca tccagaccga tgtcacggtc gatgcaagga gccagccaag ccccgtgagg
    32161 gcgcccccaa tgacggtgac cctgcgcggg ccgagcgtct cgatgtattt tccggtgagg
    32221 ggcattgcga ttgcaaagaa cgccaggaaa accgaaaacg gcaggagtat ctcgttcgcg
    32281 gtaacggtct ggcccagttc cgcggaaaaa tatgccgtga gcggcccgac aaagacgctc
    32341 caggagtaga tcgtcccgag gcacaggttg atgacgagcc cgatagcaac gagcagccag
    32401 cgcccctttt cagccggcat tcccaggact ttttctggtt ctgccatgat atgtccgtcc
    32461 gttcccaaaa agttgggatt attcttccag ggtggagaca tcacccgggt cgatgccgag
    32521 ctcttttgct ttcagaacgc ggcgcatgat ctttcccgac cgggtcttcg ggagcttgtc
    32581 cacgaactct atctcggaag gcatcgcgat cggcccgagc gtcatgcgga catggtagat
    32641 aaggtcggtc ttcagcttct cgctggggga gaacccgaca cgcaggatga cgaacgcctt
    32701 gatgatgttg cccttcatcg ggtccggttt cccgatgacg gcagcctccg cgaccgcctg
    32761 gtgcgacacg agggcactct cgacctcggc agtcccgatg ttgtggccgg caacgatgat
    32821 gatgtcatcg gccctcccga tgatcatgat gtagtcgtct gttttgctct tgacagcgag
    32881 gtcccctgcc gtatagcagt tggggatggt gttccagtac gtgcggtaac gctcgtcgtt
    32941 cttgtagacg gtgcggaaca tggcaggcca gggcttttta atgacgagga atccgccgtt
    33001 gcccggagcg acagggttcc ctgccttgtc cacaacgtcg gcgaccacac cgggaatggc
    33061 ctttcctgca aatcccgggc gcatgggctc ccccaccatc gtggtgatca tgtgcatgcc
    33121 cgtctccgtc tgccaccacg tgtccacgat gggacatttc tgtttcccga tgaccctgta
    33181 aaaccactcg aatgcctcgg ggttcagcgg ttcgcccaca gaacccagga tcctgaggga
    33241 cgagaggtca tacttgttgg gccactcttc gccgaccttc atgaacatcc ggatggcagt
    33301 cggggcagta taaaagaccg ttaccccgag atcctggata atcttccaga aggaaccggg
    33361 gtcagggtag tcggggacga cctcgccgat gacaaccgtt gcacctaccg cgagcgggcc
    33421 atagacgacg tagctgtgcc cggtgatcca gcctgtatca gccgtgcacc agtagacatc
    33481 ggtatccttg aggtcaaaga cgtgctggct ggtgtagccg gtacccacca tgtatccgcc
    33541 acaggtgtgg acgatacctt ttggtgcgcc cgtcgaaccg ctggtgtaga ggatgaagag
    33601 cgggtcctcg gcatccatga cttcgggttc acatgtcggg ggaacacctt ccatgatctc
    33661 gtgatagtcg acctccatct ccctgtgcag ttcgacgggc tgttcgatct cgcgggagag
    33721 gacgacgacc ttctccacgc tgggtgcatt gatgatggcc tcctctacga tcgtcttcaa
    33781 cggaatggtc tttccacggc gtatcgtgac gtctgccgtg atcaccaccc gggcctcggc
    33841 gtccctgatc ctcatgttga gggcggcaac cccgaaaccg ccgaatacca cgctgtgcac
    33901 tgcgccgatc cgggcacacg cgagcatggc gatgatctgc tcggggacga gcggcatgta
    33961 aatgcagacc ctgtcgcctt tcctgattcc gagacgcttc aggccgtttg caaaccggca
    34021 cacctccgtg aagagcttct tataggtgaa aatcctctct tcaccttctt ctcccctcca
    34081 tatgagtgcc accttgtttc tccggtggtt tgccacgtgg cgatcgaggc agttggcagt
    34141 gatgttgagc ttggcattga cgaaccattt tgcataggga tagttccagt caaggacgcg
    34201 gtcccacttt ctgatccagt cgaagtggtg ggcctgtttc tcccagaaac cctccggatc
    34261 ggcaagaaac tcactgtaag ccttcttgta atcctttgtc caggcgttct gcctgtacga
    34321 cgggtccggg atgtagacct tttcggagtc ggacagcggc acatcaaacg attctgccat
    34381 tttatcgcac ctttccgttt ggactcattc aatcagccat ctgtaaattc tgttacaggg
    34441 cgggcgggaa gccctgcccc tccataccct tacctgttgc actctctctc ccataagtgc
    34501 ggttgttccc ctgcgttctg tcccccgggt gcatgagcaa cccggaaatc cggaatactt
    34561 cgtgaatgcc tgattatccg accatccctc cgcggagcaa gtatgttaat gattaatcat
    34621 taaaattatt aaagctgatg atttgcttgc cgggcagatt caggctttcg gatgcttttt
    34681 tttaatggat accaatgaat gaaattcacg cagtcgcaat ccaacacgga acaggtatcc
    34741 ggtcgggagc ggtggcaacg aatcaccccg gatcccgcgc aaccggaata atccggtcgg
    34801 aaggggagaa agaaggatta acatctgcca gaaagaaaaa tggatccatg gatgttgcca
    34861 tagtcggagc ctccgggtat accggtggcg acctcatccg cctgctcctt gcgcacccgc
    34921 acgtccgcgt ggtctgtgcg acatcgcgga aactggcggg aaaaccggtc gtctctgtcc
    34981 acccccatct caaggggtta atcgaccttt cgttcagcaa cccgtcaccg gacgagatgg
    35041 atgccgatgt tgcattcctt gcagttcccc acacggcagc catggcatac gttcggccgc
    35101 tccttgcccg ggggatgaaa gtcatcgacc tttcggcgga ttacaggcta ccccgggagg
    35161 tctacgagaa ggtctacggg gtcacccaca cggactactt ccctgccccc tacggcatcc
    35221 cggaaatcca ccgcgactcg tataaaaatg ccgacttcgt gagcaatccc gggtgcttcc
    35281 ccaccggggc aaccctcgca gcagcccccc tcgcacgcct tgcccacacg gtcatctacg
    35341 attcgaaaac gggggtctcg ggtgccggcg acaacccgtc tgcgacaacg cactacccca
    35401 acgtcgcaga caacgtcaac ccgtacaagt ggacaagcca ccggcacctc gccgagatga
    35461 ggcaggaact tgcagccctt ggttcccggg caaggtgcta cttcacccca cacctcgtcc
    35521 cggtcaaccg gggaatcctc acgactgccc acatcctgct ccatgaaccc cttgaccagg
    35581 ccgacgtgga tgagctttac cggaaatact acgacggcga gttctttgtc cggctccaga
    35641 accccgtcct ggctgcggtc agagggacga acttctgcga tatccgggcg gagagcgagg
    35701 gggagagggt cgtcgtcgtc tcagccatcg acaacctcgg caagggtgcc agcgggcagg
    35761 caatccagaa catgaacatc atctgcggct tcgacgagcg cgaagggctt accggcgccg
    35821 ggctcctgcc gtgagggtga tacgggaatg ctcgttcgtg acgtgatgac aaaaaacccc
    35881 gtgacagtca gtgccggggc aacgatccgg gaggctgcag cgctgctgcg cgaacgcaac
    35941 atcggcggcc tgccggtgat ggacggtgac aggcttgtcg ggatgataac cgagtccgac
    36001 atcctccgcc tccttgagac cggcaggatc tctgacgacc tctggctccc ctccccgctg
    36061 gaggtcatcg aggtcccgat cagggagttc atcaactggg agaagacccg gcacgcgctc
    36121 accgcgatcg gggagaagga ggtccgcacg gtgatgagtc acccggtcgt gacaatcggg
    36181 gaagatgccg atatcgagga ggcagcatcc ctgatgctct cgaaaaagat agcgcggctc
    36241 ccggttatga gaggaaatac ccttgtcgga atcgtggcac ggtctgacat catccgcggc
    36301 attgcccgga cggaaacgtg agagagaggg atgtgcccat gaagagcata tgcggcgtgg
    36361 aaggtgtgac ggcctggggt gtgaaggaag gaaagttcgg gctggcttta atcagggcag
    36421 agggcgaggc agcaggggtc tttacatcga acctcatgaa agcccccgtg atccggctca
    36481 tggaggagcg gatcaggagt ggcaggcttg ctgcggtggt cgcaaacagc ggatgtgcaa
    36541 acgcctatac cggaaagagg ggttacagcg atgcccggga gatggcggcg attgccgcag
    36601 aggcagttgg cgtgagcccc ggtgaggtgg gcgtggcgag cacgggggtc atcggcaggt
    36661 accttgacct gcccctgatc agggaccagt gccaccgtgt cgcaccgctc ctctcccgga
    36721 gcgaggaggc agagacccgc gcagcccggg ccatcatgac aacagatctc acagagaaac
    36781 atgcgctcgt ccggagagag acattctcgg tcggcggcat caccaagggg tcggggatga
    36841 ttgccccgaa catggggacg atgcttgctt tcatctacac ggacgcagag gtccccgcaa
    36901 agaacctccg cggaatcctc cgggacgccg cccgcaggac attcaacagg gtcgttgtcg
    36961 atggggacat gagcacgaac gatatcgcgc tctgcacggc gaccggaacg gcagggaggg
    37021 tcccggagaa ggaattttcc atggcgctcg aggagtgctg cagggccctt gccatccaga
    37081 tcgcgatgga cggtgaaggg gcgacgaaac tcctcgaggt gacggtccgg ggcgctcccg
    37141 gcgaggaaga ggcagcaaca gttgcccgga ccatcgtctc ctctcccctc gtcaagactg
    37201 ccgtctatgg tgccgacccg aactggggaa gggtgattgc cgcggcaggc agggccggaa
    37261 tcgcattcga cccggaaaac gttgacctct ggatgggaga cggcagggag tctgtcccgc
    37321 tcgtgaaggg gggagagatc gtcgttgacc tggcccgtgc caagtccctc atgatgggaa
    37381 agaaggtcgt ctttgtcctc gaccttgcat ccggaaacgg cgaggcgacg gcgtgggggt
    37441 gcgacctcac cgaaaagtac gtggagatca acgggaggta cacgacatga agcgcgaaga
    37501 tgtcctgatg gaagcgctcc cctacatcca gaagttccac gggaagacga tggtgatcaa
    37561 gctcgggggg cacgcgatgg tcgatccggc aatcctcgag atggcgatac gtgacgcggt
    37621 cctcctccag ctcgtcggga tcaggctcgt cctcgtccac ggcggcggcc ccgagatcac
    37681 ggacaagatg aaggcaatgg gcaaggaacc gcgtttcgtt gcaggcctgc gcatcacgga
    37741 cgaggagacc ctcgagatcg cccagatggt ccttgtcggc aagatcaaca gcaacatcgt
    37801 ctccctgatt gcaaagagcg gcgggaaggg tatcgggctg tccggaaacg acggcaacct
    37861 catcatcgcc cgcaggatgg tgccgaaacg cgtccgggtg gagggaaagg aacgcgagat
    37921 agacctcggg cacgtggggg agatagagga gattaacccc tccatcctcc acacgcttct
    37981 cgacagcggt tatatccccg tcattgcgcc gattgcgatt gaccggaacg gacagagcct
    38041 caacatcaac gcggacaccg ctgccgggga gattgccatt gccctccacg cctacaagct
    38101 catcaacatg acagacgtgg atggcatcat ggatgcgtcc cgaagtcatg ttttccgccg
    38161 cctgggcgtg gcagaggcag agagcctgat ggaagagggg accgtgtcgg agggaatgat
    38221 cccgaaggtc tcctcgattg tccgggcggt caacaacggt gtttcattcg ggcacgtcat
    38281 caacggcaac atcccccaca acctcatcct ggagatgttc acggacgaag gtgtcgggac
    38341 gatgatcacg gcaagggact agggtctccc caagcagtcc gggtttaacg gaaaagcaag
    38401 gagaaataac cgggataatc aggggagatt cccgtcgccc tggcattccc tctgtttttc
    38461 ctcgctcatc tcgatcagga ggccgaagat tttccggacg gagagggggt tgatcccttt
    38521 ttcaaccgca taattgtacg catgttccag aacctcgtgg gtccgcttgt catcgtgcac
    38581 ggggaggccc tcggccatct tgacctgagc catgcgggcg gcaagatgct gcctttctgc
    38641 aatcagatcg ataatctgct catcaatcct gttgatctcg gtccggagtg cttcgatggg
    38701 catacacact ctacggggag tcaggagatt taaaggtggt gactcgtgcc cgctccaaag
    38761 ggcataaggt atgcaagttc caaataaggt acctgaaaag acatgcttga gcgaatcacc
    38821 cgccgggaga gatcagacct cctgatagcc tggattgcga tatccattgc attctccctc
    38881 atcttcatca ggggaggcgt gacactcgag acattcctcg tattcctcct catctccatg
    38941 gtcaccgtgg gtatcgggtt catccttcac gagatggccc acaagttcac tgcaatgaga
    39001 tacgggtact gggcggagtt ccggaaggat aacctcatgc tcctcgtcgc ggtggcaatg
    39061 gccgccctcg tcggtgtcgt gttcgccgca cccggtgcaa ccgtcatcta cgggacgtac
    39121 atcacgaggg aacagaacgg aaagatatcg gccgcgggac cggcagtcaa ccttgtcctg
    39181 tgtgctgttt ttgccgttct ctccggtgcc gcgggattgc tttccatccc cctgctctcc
    39241 ctcatcggga tggtcgggct ccaggtgaat gccatgatcg ccgcgttcaa catgctgcct
    39301 gtcagcgtgc tcgacgggaa gaaggtcctt gcatggaacc cggcagtctt tgcagtcctc
    39361 attgtcacgg cgttcgggat actcctggcg tcctacttca cccccctctt ctgatttttc
    39421 ccgttcccga aaagcagaac gcaacgatta aataactatg caaataattt tgatataaat
    39481 aaattaattt tgttcaggtg attgtcgcat gcacatcatg gaaggattcc tacccctccc
    39541 ctgggcagca ttctggtggg cggttgccct cccgtgcctt gggttcggga tataccagtt
    39601 gaagcgcatc ctctctgccg acagggaagc cctcccgctc ctcggggtca cgggaggatt
    39661 tatcttcatt ctctcgtcgc tcaagctccc ctctgtcacc ggaagctgct cgcatcctac
    39721 cgggacgggt ctttcagcga tctgtttcgg gccgttcatc acgtcggtca tctgcgccat
    39781 cgtcctcctc ttccagagcc tctttcttgc gcatggcggg ctctcgaccc ttggcgcgaa
    39841 catcatctcc atgggtgtcg ccggccccgt cgccggatgg gtggtctacc gtatcctgcg
    39901 cgatacacgt gtccacgtgt acctcacggt cttttgcgtc tgtgccatcg ccgatctggt
    39961 gacctatgtc gtgacctcct ttgaacttgc cctggcctat cctgcggcgg tgggaggggt
    40021 agcgtcctcg tttgtctcgt tcctcgggat ctttgcaatc acgcaggttc ccctggcaat
    40081 cgtggaaggt atcgttcttg cactcgtctt caagtacatc gtcactctca agccggagat
    40141 cctgatcagg ctcagggttt ttccggaaga gaagatccgg gctgcggcag gtgatgcccc
    40201 atgaagaaag gctatctcct cgagatcctt gccatcgctg cgatcatcgg tttctgtgcg
    40261 atcttcctgt attccagttc gctggctggt gaggcggaat ttgccggttc cgacaccgtc
    40321 ggatcggaga gggtttcgga actctcggga ataccgctcg aggagttcca cccgatcatc
    40381 ccgcagtggg agccaccgag cggcgaggta gagtccggtc tcttcgcgct ccaggccgcg
    40441 gtcggcggga tcatcgtcgg ctgggtgttc gggtactgga aaggccaggc aaaggtgaag
    40501 aaccacgaag gataacgtcg tgtgatgtac gaagagatcc tcgaggatat cgcccataac
    40561 agtgccctgc gggagacgaa taccgcggtc aaactcgcaa caggggcggg agcaatcctc
    40621 ctctgcctcc tctccccggg attttttgct cctctcttcg ttgccgtcac cctcgtcctc
    40681 gccctcgtac tcctggcccg cgtggacatt cacacgcttt tacacgtgta tacggcaccg
    40741 gcactcttcg ccctcttctc gatagcggtc atcgttctcg tctcgggcgg gggagagtgc
    40801 ttctggcgct ggcagccact tccctggttt gccctctccc tctcccgtga cggaatcaac
    40861 cagggagtgc tcgtccttgc ccgttttgcg ggggggacga cggcgatcgc tttcatcgcc
    40921 ctcacgacgc ccatgactga cctctttgcc gtcatgaagc gtgcacgcgt tcctgacgag
    40981 gtcacggatc tcgcgatgat catttacagg acgatcttcg tcatcatggc acacgtggtc
    41041 caggtctacc gtgcccagat catgcgcctt gggtacagca cgttccgcga gtccgtccgg
    41101 tccttcgcaa cgctctgcgg ggcagtcttc atcgcctcgt gggaggcggg cgaggatctc
    41161 gtccgggcga tggaagcccg gtgctatgac gggaagttcg cggtcctcgg gagggacagg
    41221 cctcctgcgc cgctctccgt cgcagcagtc gccctctttt tccttaccac cggagccctg
    41281 gcggtgacca cggcggatat cacgctcctt tagggggaat caccagtggg acgtgtcatc
    41341 ctcgaggccc gggacatctg gtacaggtac ccgaggggca tggaggcaat ccgcgggatc
    41401 agtttccaca tatggagggg agagaaggtc gcggtcgtcg gtccgaacgg tgccgggaaa
    41461 tcaaccctcc tcctgatgtt caacgggatg gtaaagccgg accgggggat aatcctattc
    41521 gacaacgagc ctatcaggta tgacagggcg gccctccgcg aactccggcg gaaggtcggg
    41581 ttcgtgatgc agaaccctga tcgccagatc atctccccga cggtcttcca ggacgtggca
    41641 ttcgggccgg tcaacctggg ttacagcggg gaggaggtca ggaaagccgt cgaaagggcc
    41701 cttgcacagg tcgggcttca gggtttcgag aggcgcccgc cgcaccagct ctccggcggg
    41761 gagaagaagc gggtcgccat cgccggagtc ctcgcgatgg acccggacgt cctcatcctc
    41821 gacgaaccaa cgacgggact tgacccttcc ggatcggaag acatcatgga actcctggac
    41881 gagctgcacc accagggaaa gaccgtgatc atctcgacgc atgacatcga gcttgcctat
    41941 ccctgggcgg acagggcaat cctcctcacc aggggaagaa tcctgcagga ggacgtcccc
    42001 gatatcgcgt tcggcgaccc ggaactcgtg aggatggccc gcctctccat gccgacactc
    42061 ctcgaactct acatcgagtt gaagaagagg ggtttttcac ttcccgaacg gaaaccaaaa
    42121 actgtcctcg acatgctcaa cgtgatcgat cgggcattcc ggaaccggct ctgctacacg
    42181 caacccggca ggataaccgt tcttgacgtg gatgccccct gcaaggtctc cctctccgaa
    42241 tggagggccc gacacccggg cgtctccctt ggtgccatgg gtacgagggc aaagcagcgg
    42301 gcagcagaag agaagatcac gcccgagttc acgtatggcg tcatcgacaa gtgcatcctg
    42361 aaggcactcc tcggggaaga cagcatgatt gtcacgaccg ggagcatggc cgggcgagtc
    42421 cgcgagagag tgcaggagtt ctcacgggag ttcaacctgg acattgaagt cgttatggcc
    42481 cgggaaaccc ttgaataacg ggaccgggac caaaaaagca gcccggcagg gccaccctcc
    42541 tgcggtgagg gggggaggta tctttcactc cccatgaagc cgggcgatta ctccgacaac
    42601 agaccggccc ttctccccag cttcagcaag tgcagtcggg tgtcccctga tgcccccgta
    42661 acggtccatg tcgtttgcaa tgatgttgtc gtaatactcg aacccgagtg tgttgaaaaa
    42721 agcggtgact gcgggaaatg ccgcgtcaaa gacgttgtcc catgaaaggc cggccgtgga
    42781 gatgaaaagg cccttgtgtt tcctgatatg gtcgtcggaa aagtacatcg tctttaggat
    42841 gaacttcctt gcccacagga actgcgccct gtcgatcagc cctttcagct cggcagtgat
    42901 gcccatgctg tagatggggg atgcgactgc caggcagtct gaagagagga tgcggtcgaa
    42961 gaggggaatg gcatcatccg agacgatgca gttcccggtc ttgtggcacg cgttgcaccc
    43021 gcggcagggg gaataggcaa gatccttgag gataaccttc tctgccacgg cccccgcttc
    43081 ccgcgtccct tcgaggaaag cgtcaaggag tgtctcggtg ttcccgtgcc ggtgggggct
    43141 ccccgagagg cccagtaccc tgacgggcat ttcaacgccc cattctcgtt ccgagttccc
    43201 tgaccacgtc gcggccaagg cgcccggcgt cggcctttgc cgaaggatgc gagaggattg
    43261 cacccttctc gtcgacgccg ttgaccatca ggtaacggat gtcccggtcg ggaatatcga
    43321 ccacgtggaa gaaacacttc acggtcggta cagccccgtc gaacacgtag tcccagttct
    43381 gaccggcggt ggagaggaat atccccatcc tctttccctt cttttcgggt gcgacgaccg
    43441 gtagtttcag gacgaatttc ctcgacctga atacctggaa ccggtcgatt aaggcctttg
    43501 cctgggcaca gatccccatg cagaatatgg gtgcggcgag gatgaggcag tcggcatcga
    43561 caatcctgtc gtgcaggtag tccatcccgt cgcgctggac gcacttgttc agtttctcgc
    43621 aggcattgca tcccctgcac gggtttacgt ttgcctcggt gaggacgacc ttctcgatgg
    43681 caacccctcc ctcctgctcc atggcctgga gaacccagtc gagaagggtc tcggaattgc
    43741 ctccccgccg cgggctgccg gcaaaggcaa ggactttgat ctccatcagt caccccttgg
    43801 gcccggcagg tgaaaaatgt gtccaagggt gcaagggtcc ggatcaaaaa aaggagaaac
    43861 gggtgtatta cagtttcttg aagcagaggt accagtcttt gcactcgtac ccctcggaga
    43921 gacgcttgtc catctcttcc ttgttcttcg gtgcggggac cacgaccttg tcacccggct
    43981 gccagtttgc aggcgtcgcg actccgtact tgtcggtcgt ctgcagggac ttgacgaggc
    44041 ggatgatctc cggcatgtac cgtcccgcgg tgagcgggta gtagatcatg gccctgagta
    44101 tccccttgtc gtcgatgaag aagacagccc ggatcgccgc cgtgctgctc tgccccgggt
    44161 ggatcatgcc gtacttcttt gccaccttca tgtcgaggtc cgcgatgatg ggaaacggga
    44221 tgtctactcc catcttctcc ttgatgttcc ggatccacgc gaggtgggag tggaccgagt
    44281 caatggagag acccatcagc tggacgttga gggacttcaa ctcctcggcg atctgggaga
    44341 acgcgatgaa ctccgttgta cagacgggtg tgaagtctgc cgggtgcgag aagaggacga
    44401 gccacttccc cttgaaatcc gaaagtttta ccattccagc cgtcgtgagg gcctcgaagt
    44461 caggggccgg ttccccgagg acaggcatcg atccgaattc gccgcacatg cggactcact
    44521 ccggcatgac ttcgtcaagc tgtgccttgc catagacata ggcaggcatg cccgcgagga
    44581 ggaaggcaac ccgcaaagct tcctcgactt ctttcttggt tattcccagg ttctttgcac
    44641 ctgcaagctg tgcccttacc gcgtgctggt cacgcaggga tgccgcgatg gcaattgcaa
    44701 tcagtttctt cgtcttgcgg gtgagggcgc cgtcgtccca gatatgaccc tcgagtttca
    44761 tcaccatctc gtacatctgg gggtcctttt ccgcaagttc cctgaaaaat ttcgggacct
    44821 tgccgatcat cttttccaga tttttcgtgt cctttgccat acgtcgatca cttcacgagt
    44881 ttcatgggct gcccgcagca gacgagctct ccgccgccga cttccttgac tacaacaaca
    44941 ttgccgcaga tctcgcattc gaagacctgc ccgacctttg agacattgac catttccttt
    45001 cactcctcat cgttggacat tcatcattcc attctgttcg gggctgcatg ggaaccggac
    45061 attcatccct gttccggctg cctgttttct ctgccctgca ctgcgcagtg gcaaatcggg
    45121 taaaaatgag tgttacaggt tgctcttgcc gcgcttgggc ggattcatcg catcctccgg
    45181 ggtcttgatg tccgggcgga tgtgggtcat cgggaaacac tggtattctt cgcaggcaca
    45241 ctgggggcat tttcgcaggt cctgttcagc cttgtccagc accatttcac gcccgcagtc
    45301 caggcagaca tacttgccgg gcccgacttt ctgcccggcc ttagccttct cggtcagatc
    45361 tatcaccaag acactacatg gttggagaga ttcatatatc tttggttctt cacccgtttc
    45421 ggatgaaggg gcgtattttt tgagtctttc tgattattcg tgttccggac cgcggtcctt
    45481 tgcggaccat cgcagttaag tggatggggg ttgattccag ctccatggga ttccggattg
    45541 ctggtctcct gggaagcccg cttgcgggag gaaacacggc aaaactcctc gaccaggcgc
    45601 tcctcggggc acgcgacgcg ggctgcgagg ttgagcggat cgatgtcggc gacatggtgt
    45661 ttcgcccctg cagggagatc ttctactgcc gggaacacgg gacgtgtgcc atgaaggacg
    45721 acatgatccc cctgtaccgg acattcgcgg aactggacag cctaatcgtt gcgacacccg
    45781 tgatgaccat gggaatcccc ggggccctca agtcattcat ggaccggttc caggtctttt
    45841 tcatggcgaa gtacatgagg aacagcccgc tcgttcctga agagaagagg gcccatcgtc
    45901 gcggcctcta tatcgggata gccgggatga acgtgccata cgtcttcgat ggtgcgaaac
    45961 tcacgatgaa ggcattcttc tccatcatcg acgtggagta ctgggacgag ctcctgacgc
    46021 gtgacatgga caccatcagg gacataacga cacgcccgga catcatggat gaagcgtacc
    46081 gcaagggttt ccgcctcggg gaactcctct ttgaaaaaaa tccctgaatc agaaggaccc
    46141 tctctcccgg aggctcgtgt atcctgaccg ggccacgatg acgtggtcga gaagcctgat
    46201 cccgaggatc tcgcctgcct ccttcagctg cctcgttatt gcaaggtcct gctggctcgg
    46261 ctccagcgaa ccggacgggt gattgtgaac gcagatgact gcagcggcac ggtccgtgat
    46321 cgcatcggca aagacctcgc gggggtgaac gagactgtgg ttgaggaggc cgacggtgat
    46381 agtcctcttc tcgatcacct cgtttgcacc gttgagcgtg atgcagacga agtgttcctg
    46441 gctctttgtg gcgagatctg caacgaactg gaggatgtct gcgggacact ggatacgtgt
    46501 ccgggcttct tcccgccgga ggtaacgccg tgccagttcg agggaggcaa ggatctgcgc
    46561 cgccctgctc tgcccgatcc ccgggacacc aacgaggtca ttgtaggaga catccccgtc
    46621 ccggctggaa aagagtcccg cgatatcttt tgcaagggaa aaaacatcgc ggtcaggtgt
    46681 cccgtggccg atgattgccg cgatcaactc gtggtccgag agggcccggg ctcccttttt
    46741 tgcaatcttt tccctcggcc ggtcacaggc agcaatgtcc ctcatccgct tcatgcgatt
    46801 gcaggatgat cggttgcagt gcggggagaa aaaggcgggt gatctgttcc cgggaacggg
    46861 ggtctcctgc aaggatatgt atttacctca cttctcccga tatatgacca tggcgacaat
    46921 ggaaaatgca atggaggcct ttgcaggcga atcccaggca aaccgaaagt atgccgcatt
    46981 tgccgagcag gccgagtcgg aaggattcaa aaatattgca cgtctcttcc gggctgcatc
    47041 ggaagccgag gcaatccacg caaagaaact cctcaaggcg atgggaaaga tcagctccac
    47101 gaaggagaac cttgccgggg ccgtctccgg cgagacgcac gagtatacgg agatgtatcc
    47161 cgcatttctc aaggaggccg aggcggagaa gaagagtgat gttgccctcg tgttcacgta
    47221 tgcaatgaaa gcagaggagg tccatgcgac cctctacagg gaagccctca acaatctcag
    47281 ccacggccag gacatgtcga accggactgt atacctctgc ccggtgtgcg ggaacgtttt
    47341 cctcgggaac cctcccgaca agtgcccgat ctgcatggcg gtcaggaaag tattcaagac
    47401 catcgaatag gacacccttt ttttctcccg gcagtattga acagaagccg ggcggagccg
    47461 accccggaga aagagatacc cggggtgccg gactgacact tttattaggc atccccgtca
    47521 attccccaga catgcccagg gtgactgtct attacaccca gaactgtcct tactgccgca
    47581 tggcaaaggc ctacctggac cggcacggtg tcgactacat ggcaatcgac gtgggttctg
    47641 accgggaaca ggcagaaaag atggtcaggc tgtcaggcca gtacggcgtc ccggtcatca
    47701 ccgtcgatga cgaggtcatc gtcgggtttg acgcggaaag gttgaacgag ctcttcggca
    47761 ctgcacaggg aaagggaggg gagatcttcg atgtcctgat catcggggca ggacccgcgg
    47821 ggcttacggc tgccgtgtac tgctcgcgca agatgctgaa aacaatcatc gtttccgaga
    47881 atatcggggg tcaggctctc gagagctggg ccatcgagaa ctacatggga taccggatgg
    47941 tctcgggggc agacctgatg cggaaattcg aggaacaggt cagaaccgag cagaacatcc
    48001 acatcgacct tgaccgcgtg cagtcgctcg ggcgggaggg ggagtccttt gtggcgcaga
    48061 ctgcgggcgg aaagacgtac agtgcgaggt ccgtgatact cgcccagggc aagaggcccc
    48121 gcaagctcgg tgtcgaaggg gaggagcgtt acctcggccg ggggctctcc gtctgttcca
    48181 cctgcgacgg ccccctgttc cgcgacaagg ttgtcgcagt cgtcggaggc ggaaactcgg
    48241 ccctgcagac agcaatcgag atgagcaaga tcgcaaggga ggtccacctc gtcgtccgga
    48301 gcacgatcaa agcagaccct gcctacgtca agcagtacga agagaggaag aacatcatca
    48361 cccatctcaa ccatacagtc tccgctctcc acgggaacgg catgctgacc gggatcacaa
    48421 tccgggacgg caggagcggg aaagagacga cgattaccct cgatggcgtt tttgcagagg
    48481 tcggatgggt cccgaacacg gatttcctgg gtgatctcgt ccccctcaac gaccaaaaag
    48541 aggtaattgt tgatatcaac tgcaccacgg ggacccccgg tgtctttgca gcaggggacg
    48601 tgacgaacat ccggacaaaa cagatcataa ctgccgccgg ggagggtgca aaagccgcgc
    48661 tcgaggccta tgcatacctt acccggtgat tttttagtaa tttaccaatt agatcaggat
    48721 tttatactaa ccgcaggttt ccggttgaat aaactatcat aggactcact caatgcacga
    48781 atgccaaaga gattgaacag acctgtttca tggatcaggg aatcctcatg acactcgggg
    48841 aatgaccatg ttggcaaagt aaaggttcaa ccgagtcagg aggttcaatg acaagtgtaa
    48901 ctccagtcat cgggaatagt gagtcaggtg taagagtatc cttggagttc tgaaaaattt
    48961 taaaagatca atgcgactgc ttcaatcggt tattgtaaag atttaacggc ccgaggcgga
    49021 gtatatcaat gtcttctgtt tttatcaaaa ttggccccag ggatactccc tgataacccg
    49081 gtcaaataga tcttacacaa ctttggagag acgaaaacta ccagaaggaa agatacttcc
    49141 ataaacatac taataaacct tattattttt taaggattat tttttccctc ttatttcatt
    49201 ttattctggt tgagaagaga cattcaagta attaattgtc atccgaactt attttgagaa
    49261 aaaaaggaag gcggattcct tgcacatact tcagtgacaa gtccattgcc cccggatatc
    49321 aggataaaaa gatgttaaaa ctcaataaaa aagctctaaa tgaaaattga gtttaaattt
    49381 caaatatcac atcttcaaca tggtaaaata aaaaacaaaa aaatataaat aataaatggt
    49441 agaagtaata ttccaagtga taagatggta tctgggaaaa gaacgattca actctttctg
    49501 gggttaatgc ttctgggatt gatcgtctat ccatgttcat cggcagatcc cacaggggct
    49561 gcgactctgg aagaaaaacc cgatgcaccg gtgaacttct cttggaccct catgtgcggt
    49621 tttctcgtga tgttcatgca ggccgggttt gctctcgtcg agaccggatt gacgcgggca
    49681 aagaacgctg ccactatcgt tatgaaaaat ctcatggact tctgcatggg tgcactatcc
    49741 tactgggcag taggttttgc cttcatgttt ggaactgcaa cagggatttc aggacttatc
    49801 ataggttttg ataaattctt cctcatgggc gaagcatacg acgtgagtac gatggaactc
    49861 tggttcttcc agctcgtatt ctgtgccact gcggctacca ttgtctctgg agcagtggct
    49921 gagaggataa agttctctgc gtacatcatt tacagcgtcg tgatatcagc gataatctac
    49981 cctatttacg gtcactgggt ttggggcgga ggctggctgg cttcgagcga gttcatgacc
    50041 acactcggtg gtggctatgg ggcgctggat ttcgccgggt ccggagttgt gcatgcagtc
    50101 ggcggtttca tggcgctcgc cggtgcatac cttctgggtt cccggattgg aaaatacaaa
    50161 aaagacggga caccggttgc aataccgggt catagcatca ctcttgcgat gcttggggtt
    50221 ttcatcctct ggttcggctg gtttggtttc aacgcaggga gcacccttgc agcaacagag
    50281 ctccatatat ccatcatagc agtcaacaca gcacttgctg gagcagctgg cgcaatggtg
    50341 acaatgttcc tgacatggtg gcggttcggg aaacctgatg tgagcatggc cggcaatgga
    50401 gtcctggccg gcctcgttgc cgtgactgct ccttgtgcat ggattaaccc tgttgccgca
    50461 gtgtttatcg gagtgattgc aggggtcatc gtttacatgg gtgtgtggtt cctcgaccat
    50521 cgcctgcaca tcgatgaccc ggtcggtgca gtctcggtcc atggattcaa tggtatctgg
    50581 ggtctcctgg cgcttgggct ttttgcggat ggaacctatg gagtatatac cacgcagggt
    50641 cctatggtaa ccggacttct ctacgggaac gccgggtttt tcctctgcca ggtgattaac
    50701 tccgttgtag tatttgcatg ggcgttcggg ctgggactga tcctcttctg ggttctgaag
    50761 cacacgattg gcatccgggt cagccgtgaa gaagaactcc agggtctcga tatcggcgaa
    50821 catggaacga gtgcctatcc aaacttcgtg accactgaac ctgcagtaga tggtgatatc
    50881 gcatgaaaaa ggtcgaagcg atcataaggg caacaaaatt cgaggaggtc aaactcgccc
    50941 tcgaaaaggc tgggatcgag tccatgaccg tgatcgaggt aaaaggaagg ggaaaacaaa
    51001 aggggattac ccagcagtgg cggggtgccg agtacgtcgt tgaccttctt cctaaaacca
    51061 agatcgagat ggtggtagat gatgccaggg tcgagacagt ggttgatact atctgttcag
    51121 tggcagcgac cggaaagatc ggtgatggaa aaatcttcat cagcaccatc gacgatgtca
    51181 tccgggtccg tacccgggag cgtggtacca cagcactctg accgatcctg aaggcccgcc
    51241 tcttccctct ttgggggtct aaaaaccatt tttttaacaa aaaaagaaga ttttgaatca
    51301 ggcaaggaga ttgatttgat ccttaagggt atgcaccaac ggaaagtcac tattttccag
    51361 catgtaagga atgaacacgg cggtctgttt gaggaatata tcagggagcg cgggatggat
    51421 atttttcatg ttcctatcga tgaaactaat gaaattcttc catttcattc gacgcatctt
    51481 cttatccttg gcggcccgat gagtgtcaat gacgagaaag agtacccttg gttgaaggaa
    51541 gaaaagcaga ttatccggga atgggtggcg gaaggacgac ctgttctcgg tatttgtctt
    51601 ggtgcacagc tgatagcttc ttccattgga gcagaagtcc atccttgtca ggaagaacga
    51661 gggtggtcgt cggttatttc cgtaaatccc aggatttttc ccgatcttcc cctccgattc
    51721 agggtgtttc agatgcacgg ggaaactttc gaaatccctc acaaagcagc attggttttt
    51781 cgtggagaga acgtgtgcaa tcagggactc tgtattggaa gtgcactggg catacaattc
    51841 catgtcgaac ttactatcag aatgatccag gactggattt catgccttcc tgatcaggaa
    51901 cagtcattta ttcttgcaca aagcaggcag tatcttccgg aaagcgagaa tatctgcaga
    51961 attattgcag accggtttct atctgctgct ccgtatgatt tttcatgggt acatcccgga
    52021 aatggcactc ctgtgtgagt cctttgtatt gttatcgtct ctctcgcacc gaagaaatgt
    52081 gaggcatcgc ctgcatcgca tcgccgggat tcacctggtt atcatggaaa ggtgctgaag
    52141 ttgtctcaat gcgccttatc gcaatcaggt cagaatcgca aagagatctt tacccctcac
    52201 tccctttccg gaacaccacg atcctgttcg tgttcgtccc gg
//
LOCUS       DAOOJU010000013        45591 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_918_length_45591_cov_16.109210, whole genome shotgun sequence.
ACCESSION   DAOOJU010000013 DAOOJU010000000
VERSION     DAOOJU010000013.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 45591)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 45591)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45591
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_918_length_45591_cov_16.109210"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(131..1303)
                     /locus_tag="PK679_04860"
     CDS             complement(131..1303)
                     /locus_tag="PK679_04860"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HPC55322.1"
                     /translation="MYDLARLREEFPVLERCIYLDSASTSQTPRRAVEAMCAYFYEYA
                     ANHGRGSHRLARRTTEEYERTRDVLARFLGVPSDTLVFVRNTTEAINLVANGMSWERG
                     DEVVTTALEHHANLLPWMNLEKRGVRTVVVPHHGGMVDPGDIGGALTKRTRLVAITHM
                     TNVLGTVQPVEEVADIAHDRDVPVLLDAAQSAGHIPFDAGKFDFVAIPGHKGLLGPQG
                     TGILYASDLSLLSPCILGGGIVGEVTLDGFSLLPPPARFEAGTPNIPGVIGLGAAIGL
                     VMELGVDNIHRHETTLACLAHDGLSALPGVGVYSPRGSPVISFNVTGMNPHACAAELD
                     RRRGICVRSGFHCAQPLAASLHPAGTVRASLGCYTTGEEVSALVETVREIAGSLTG"
     gene            complement(1357..5220)
                     /locus_tag="PK679_04865"
     CDS             complement(1357..5220)
                     /locus_tag="PK679_04865"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed DNA polymerase II large subunit"
                     /protein_id="HPC55323.1"
                     /translation="MIHCSPAMEKYLAGLEEGLSRAMEVAGKARALGLDPRTGVEIPI
                     ASDLADRVEALLGIPGIASRIRELEGQMSREEAALRIGLDFVQRRFGEQSREEVLDHA
                     IRTAMAILTEGVVAAPTEGIAKVGTGKNDDGSEYLKIYYAGPIRSAGGTAQALSVLVG
                     DFVRRELGMNRYIPRPEEVERYIEEIRQYNSIMNLQYLPSDHEIRLIVQNCPVCIDGE
                     GTEQDEVSGYRNLERVETNAVRGGMALVLAEGLALKAPKVLRYVRALSMDGWDWLEEL
                     IRGVAKPGEGENGGAIAPRDKYLRDLIGGRPVFAYPMRKGGFRLRYGRSRNTGFAAAG
                     LSPATMHILGDYLAVGTQMKIERPGKAAGIVPVDTIEGPTVRLKNGDVLRIDDAEVAV
                     RLKDEVDRILDVGEILIGYGEFLENNHVLVPPAYCHEWWCQEGGKERPKTEEEAIAQC
                     FEGAFLHPDFTFLWDDISPAEVREIADYVSEKGEIRHGILVLPPDPRIKYLLEEILLP
                     HRVREGQICISEYLVFLACLGLDLKLKRRPAWDSVPGGSDTLALVSHLSGLPMRSRAG
                     TRIGGRMGRPGKSRPRKMNPPPHGLFPLGDAGGNRRSFQEAQAHAPQPNMDGGVITIE
                     TGRRRCPSCGAETFRNRCACGSHTEPVYTCPRCRREIGSDTCPACHVPATCSATTTLN
                     VRQEYMAAVERLGLRENAITLVKGVRGLISREKTVEPIEKGILRAARDIFVFKDGTVR
                     FDMIDLPLTHIRPAEIGVSPDKLRELGYDADIDGKPLTSPLQVVELRPQDILVSDSCA
                     GYMVRVAQFIDELLEKCYGLSPFYRVSSREDLLGHLVIGLAPHTSAGVLARIVGFSRA
                     NVGYAHPFFHAAKRRNCFHGDTLIETFDGKEWSTKPIRQIVAENFDLSQPGIDRLGTY
                     YSDPQSTLLVRTVDTEGKPHLRRVTSVSIHRAPAALIRFETRGGRSIVVTPDHAMLLW
                     DVCFLRKIRAVEVKEGDAVPVMVGMNVLADHIARRDVIPCPDDRVFCLTVTDEHTVCA
                     NGIFTGQCDGDEDCIMLLLDGLINFSRSFLPETRGGTMDAPLVLTTRIDPAEIDKESH
                     NIDVGSGYPLEFYLAALRYAHPREVEGLVDRVGRRLGTPAQMEGFSFSHDTTDISAGP
                     IESMYTQQKSMIDKLQKELDLAEKIRAVDEHDVAERVLTTHFIRDLMGNLSAYSRQKF
                     RCTRCNASYRRMPLAGKCTRCGGNIIPTVHEGSVKKYLEVSRDICTRYRISDYTRQRV
                     AVLDMAIESTFGQEKSEQKGLADFM"
     gene            complement(5353..5853)
                     /locus_tag="PK679_04870"
     CDS             complement(5353..5853)
                     /locus_tag="PK679_04870"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC55324.1"
                     /translation="MREEEIAEQVRVLAQGDLAARRSAVKTLAAAGGTAVPALVRFMA
                     ETDNDDARWYAAVALARIGPPGIDPLIEAIGKNSDVRFRRYAAAALGHIGGPAVRPLI
                     AALSTKDPSARGFFAQALCRVGKAAVPALRAALGSADPDMRQYAAMILWQMGEEGIDA
                     LMSGPG"
     gene            complement(5850..6698)
                     /locus_tag="PK679_04875"
     CDS             complement(5850..6698)
                     /locus_tag="PK679_04875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HPC55325.1"
                     /translation="MVFESLSIPVIGTVTLLDLLVFAIAVFVVYIISRIVAIYLKKAF
                     SDRVDPVELDKLVKVIQAAIIIVGVYAALPRFDINIADMVVVGGTIGLVAAFAGQRIV
                     SNFGSGLFIIAERPMKPGDNVTIGEVSGTVDQIRVLSTIIKTYEGVYVRVPNEKVFTS
                     EITNYVANVARRFEYSIGISYRSDAETAIRIIRSLLEDHPFVLAHPAPSVFVDSLAES
                     AVIIRVFIWAPSRVWWSVRTEMLWTIKKALEEAGIEIPYPQRVVTIAPGARIEVSHAH
                     GGGDIR"
     gene            complement(6707..7474)
                     /locus_tag="PK679_04880"
     CDS             complement(6707..7474)
                     /locus_tag="PK679_04880"
                     /inference="COORDINATES: protein motif:HMM:NF016166.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF432 domain-containing protein"
                     /protein_id="HPC55326.1"
                     /translation="MSGTGSRSGICSRRPDLFSVFGRYGIPFRLGESGITVETRTEGQ
                     FTLYERVAPSGRVERRLGFSGGTITINPVEPVNLPQEVTNTIEFHFTPIAIEPLSEVT
                     VFLTFPVEIGVFSGSEGSYTLIDVFSLAKPKYSLYGTPEKGVITRHVETGVSHEPPPV
                     DPLQEGILALAIRNTGKDWVWVSRAVFESPSLRIFYGPHAAMSAEMMVYSRILGETWV
                     TRTPPREGMEEAIRIFPTKKSLVPEKPSYLMEYGVGD"
     gene            complement(7471..>9034)
                     /locus_tag="PK679_04885"
     CDS             complement(7471..>9034)
                     /locus_tag="PK679_04885"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC55327.1"
                     /translation="CDRRNNRAFREEPVTPAPYFPDSFFWDRGSPRWVVRTACRDPSP
                     ATAQGTVAAAVSRIASEKTGILRLTNPDLREVEKHTRSLPAWNDGRVLFSVPQDLSEG
                     LCHPDSMNLLRPAREGLDRPKIAIIVFLVAVSVILELVVHVGLGMETVYSHFFYVPIV
                     LAAAWMGIRGLPVSLFLSALYLADTALLSGTIGPDSSIRAGMFVLVSLVIGLVSDSAR
                     RKHREAMAGTGDAEARTATARRGAFPRGDALLRHIGPPNVDRMRVERDVPGLVRALGH
                     KDPAVQYAAAEALGELREPSAVAPLMEVLTADRYSGVRWKAAEALARIGEPAVVPLIG
                     ALHHPDEDVRWKAAIALGEIGDDRAISPLIELLGDSDRFVQSRAAYALGEFGTRAAPL
                     LRLALANGPQPVRKGAVLALRKIRDPAALDDLTRALGDPDATVRSAALEALMQHGGEG
                     YRHIILYLSAAPVAERAGVFQAIRDIPNQKLLKGFVPLLSGADRKSREFILSVIDAGE
                     RHEGPGERPAGP"
     assembly_gap    9035..9134
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(9146..10339)
                     /locus_tag="PK679_04890"
     CDS             complement(9146..10339)
                     /locus_tag="PK679_04890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitase X catalytic domain-containing protein"
                     /protein_id="HPC55328.1"
                     /translation="MRLSSEEEAILAGEQGETRARMLEILIALGKVYGAERLIPIRSA
                     QVSGASFKTIGRYGLEWLQQLDARVAVPTVLNPVGMDRERWQEMGIDPGFARAQEEVI
                     AAYRKLGLALECTCTPYYLYVTQYGDHLAWSESSAVVYANSVIGARTNREGGPGALAA
                     AIMGRTPEYGLHLVSQRRPEIVVRVEGGASLSDPALFGALGYHVGKLVGGRIPLFEGI
                     SPRRDNLKALGAAMAASGAVALFHVAGITPEARIFSFSTGDLEVITVEGKEIETIMEE
                     IPVEAVALGCPHCSPQELGTIARLLEGKVTKIPCYVFAARGVIERHRDDVAVIEASGA
                     RVFADTCMVVSPAMERFRAIMVNSGKAFSYVPDMCGAAVRLGTTEECIGVATGETTGR
                     SGKNR"
     gene            complement(10348..11583)
                     /locus_tag="PK679_04895"
     CDS             complement(10348..11583)
                     /locus_tag="PK679_04895"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HPC55329.1"
                     /translation="MREFIELMREKGAVIDVEECPEGEFGAPRMASRTDSLLLFHDLP
                     GGRAAMNLTATRKALGLALGVDENRIAETLARASYEGRIVREDPLPMGKADLSRLPVM
                     KFFPGDAGRYITAGIVFSAYGGVENASIHRMLVLGPDRVAARLVEGRHTFTMHREALA
                     AGDVLPVAVAIGVHPAVTFASCTRVPKGRELAFAAELMGGEVRVRRCRNGVCVPEAEI
                     VLEGFIGAETAEEGPFVDITGTYDSVRMQPVIRFTGMYARPDAIYHSILPGGHEHRIL
                     MGVPYEPVIFRAVSAVTTVRNVVLTTGGCGYFHAVIQIRKSTQGDAKNAILAALAAHT
                     SLKHVVVVDEDIDPADPAEVEYAIATRVRGDRDILIIPGARGSSLDPCRMADGTNVKV
                     GVDATMVLGHEHEFTRAGW"
     gene            complement(11701..12144)
                     /locus_tag="PK679_04900"
     CDS             complement(11701..12144)
                     /locus_tag="PK679_04900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55330.1"
                     /translation="MIEYWTMVIAGVVAVAAITSCAYLYAKSRELRLVQNRQKLKVYN
                     DFLCAVTRLTVAGGDAYALSQAKRNLAFVLNRVNLVAGPEVLGHVNELLDFLNETREG
                     DYDVLKEKNILNAIVQAARRELDPESARALEEAQFRYRFYNPPRT"
     gene            complement(12354..13562)
                     /locus_tag="PK679_04905"
     CDS             complement(12354..13562)
                     /locus_tag="PK679_04905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HPC55331.1"
                     /translation="MGAKIIKDPVHGYVEVEDPFLPLLDSPLLQRLRYIRQLGFSYLV
                     YPGAHHTRFEHSLGTMHLAGVMARQLGLAARDQALVKAAALLHDVGHGPFSHAIEPLA
                     GEYLGRHHQDVSLLLGRSDVREVLGAMGIDAGDVASLIQGTHPLSGIIHGELDVDRMD
                     YLLRDAHYTGALYGTIDAHRLIRNTFVMDGHLVLADAGINAAESLLIARTLMRPSVYF
                     HHVSRIGEMMFQEAIMAHVARDPARGLEALIRADDSACMQALLSSPDPVARDLSRRIY
                     ERRLYKRALYIGRDRVNTAHMARYASFERRKEIGKKVAEEAGIAPSCVLVDIPPFPGD
                     MSLSVQVRHRHMAVPLSEVSPLLHTLNETRRGQWRLGVYTPPEFREQVGEIAADILHV
                     RPLTTQEPLF"
     gene            13607..14545
                     /gene="cofD"
                     /locus_tag="PK679_04910"
     CDS             13607..14545
                     /gene="cofD"
                     /locus_tag="PK679_04910"
                     /EC_number="2.7.8.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043743 - LPPG:FO 2-phospho-L-lactate
                     transferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-phospho-L-lactate transferase"
                     /protein_id="HPC55332.1"
                     /translation="MIVLLSGGTGTPKLVQGMRMVVPDSDITVVVNTAEDIWISGGFL
                     SPDIDTLIYLFSGLLDTGTWWGVAGDTFVTHDALLRLGSDEYIAIGDRDRALQIRRGE
                     MLREGLTLTEATEALCSIMGIDARILPMTDSPVATLIRTTGRTIHFQEYWVRHRGQLR
                     IDEVVRQWDGPARATSRVLSSIRESEGVIIGPSNPVTSILPILECGGVRDALREVPVV
                     AVSPFIGDTPVSGPAAALMKARGCSPDSAGTYALYRDFVDFFVQDVRDPVSVPGAIRA
                     DTLMKTPLVARDLSVLALSLIREARGRTRSPSEKDR"
     gene            14591..15847
                     /locus_tag="PK679_04915"
     CDS             14591..15847
                     /locus_tag="PK679_04915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC55333.1"
                     /translation="MSIFRSLRGALGREGDKSPDEAEKERVESVRNALAYGDMEARWN
                     AIRAAGELGDAFIDPLINALNDEHWIIRRGAAQTLAKIGAPAVPPLIEMLACEDESVR
                     REVVQAFILIGDTSVESLIRALSRDQPAIREGAAQILGEMGVQSAVGPLVEALKDKEP
                     RVRKQAAIALKMIGHPDAISPLITLLGDESGYVRIAAAEALCSLGDRAIGPMIAALAH
                     PQPELRQRAGLALAAIGSPAVEPLIAALDHEDPLVRQGAAGVLGRIGDSRAVPGLVRL
                     LGDPVRNVRQECVKALSTLGYPAISPLVSAFREGDMVIRNCAMEALWLIGGPAVRPLL
                     DLLDDSNPDVRRRTALLLGEMGYPTAIEALTRVLGDQVPAVRREAFEALEKIRKKQPE
                     GTPPLPKAEKGGNEPARNSSPSAKKA"
     gene            complement(15859..16395)
                     /locus_tag="PK679_04920"
     CDS             complement(15859..16395)
                     /locus_tag="PK679_04920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55334.1"
                     /translation="MERCALRPALVVLLVTLLVATGCMVPQTQGGEGRGSPGGTPGIT
                     PVPTASPQVQETVTVAAVVPVEAERSPRPLAPGAVYRAGDTLTISGETILSPGNHVLV
                     QVTPVAFGPTKKGAGLPVSGVSGVAPVTRQEGAAFSRWSFGFDTTGWEPGEYMVRVEG
                     IEVPDFSLDLRFALAAAG"
     gene            16502..17149
                     /locus_tag="PK679_04925"
     CDS             16502..17149
                     /locus_tag="PK679_04925"
                     /inference="COORDINATES: protein motif:HMM:NF014043.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="HPC55335.1"
                     /translation="MPQGERQSSREEVVLALNAKFPVMRKLFGVKKIGIFGSLARGED
                     RPGSDADIEVEFEPGMDTYANYIGLALYLEELLGRRVDLVLSRVLASYLRPELGAMHA
                     AISRDKVYLARILDEIAFLSHRTRGISARDFLKDETLRRAVARSLGVIGESAERVSEQ
                     TRKDTPKIPWKELEGLRSHLLHPYFSMDWSLVWNVLNVYLPTVEPLIRAAHSRIA"
     gene            17277..18257
                     /locus_tag="PK679_04930"
     CDS             17277..18257
                     /locus_tag="PK679_04930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55336.1"
                     /translation="MIHSYNLSPVLRELLEMTESMLGIEIQLVRRTDVPPQGLLIDEF
                     TYGTGKNVIAFSSALLGTLKDYTICRNCIELLARGCAARRGNHKVLSFSKESALEGCR
                     QIYLDILKDEGTRNLPVWQKKQLVFLLFMLLHEVFSEMPLKLLADLVISHRFSLLRNA
                     QVYSLLKESMRDMHDLVPVKDFLPQRYYVVHNAVYYARDMVLAYTLSEYKLNPVINIP
                     ELQRFKNLDMKEMMTHRWSRSPWYHTKVVGDALSNMLKRTIEMDFSREFSMDYFYELY
                     VLSTEIPARWWVMMGMQDWFLWDSPEARREVLASQAAIEKFVREEIFGPD"
     gene            18326..19618
                     /gene="aspS"
                     /locus_tag="PK679_04935"
     CDS             18326..19618
                     /gene="aspS"
                     /locus_tag="PK679_04935"
                     /EC_number="6.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050560 - aspartate-tRNA(Asn) ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006422 - aspartyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA(Asn) ligase"
                     /protein_id="HPC55337.1"
                     /translation="MRIPVREVTPGCETAEICGFVHEVRDLGGLAFLLVRDRTGIIQV
                     TVPKKKVAPHIIDAVRDVSRESVVRVKGTVRAIDKAPGGREIIPEVFEVISKSESPLP
                     LDVAEKVPAELDTRLDSRFLDARRPRVAAVFHIRSAVAQAVHEYLFSAGFVNITTPKI
                     VAAATEGGTELFPIAYFEKEAFLNQSPQLYKQMMIGAGFEKVFEIGPIFRAEEHNTTK
                     HLNEATSIDLEMAFADQNTVMEILEDLIVSVYRKVEKDCGPFLEAMELDGFSVPKTPF
                     PRLPYAEAIEIAGKKTDEPIRYGDDIGTAAEKAIGEEMGGHYFIVDWPTAIKPYYAMP
                     YEDDPSICRAFDLMHPRMELSSGAQRVHQYDLLVAQIREKGLNPESFSFYLTPFRYGM
                     PPHAGWGLGMERLVMTMLGLPNIREAVLFPRDRHRLVP"
     gene            19615..20532
                     /locus_tag="PK679_04940"
     CDS             19615..20532
                     /locus_tag="PK679_04940"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HPC55338.1"
                     /translation="MTIPDLFAALPVLPTTVVGSFPVDTGRGLPGLLFPLRHAVQKAV
                     ESQVRAGIDIISDGQVRGDMIRAFSSRLPGIRGQDVVSTVLPASGSITVADTRYALSR
                     HRFVKGILTGPTTLSFGLHIATPVYRDRADLAMDLARALAAEAKALESAGVCMLQVDE
                     PVLSTGAADVAGAERALKVLLEGIHVPVCLHVCGDLSSVIDRLLAFPVDVLDIECAKT
                     PQNLELVSERDLREKRIAVGCVDSGTPRVEDEDEIARRVRDAVDRLGAGRLLVDPDCG
                     LRMLPFDSATGKLSRMVSAVRKVREELAG"
     gene            complement(20548..21132)
                     /locus_tag="PK679_04945"
     CDS             complement(20548..21132)
                     /locus_tag="PK679_04945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HPC55339.1"
                     /translation="MARENRRSTGISGLDLAMEGGFPAGSTIVVQGSPLTGIDLLARQ
                     FWSADGMTGTYLMIDSEVEPGMTDARHSPPEALLPLMKGDRVVLDSLSTIITRNGIDA
                     AISLLSSVKKDIAERKANALFILYSDLHTTVEEIRIMRMADVVIELKEIIIMTEIERQ
                     LAVHKVRNAQVPKRIIPFNITEKGIELSTTSRVV"
     gene            complement(21200..22756)
                     /locus_tag="PK679_04950"
     CDS             complement(21200..22756)
                     /locus_tag="PK679_04950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HPC55340.1"
                     /translation="MRTGPLPRFNISTFLEARAREPDRCAVIWPSKGEKYTYRELFRK
                     VSALSAALREMGIERGDRVCIYMDSCPAFLISYFAVWRAGAVAVPANSALREGELAYL
                     LADSGARALICGGGEMEVAERIRDNPAFPSLVICTGRAGDGVLSFDTLAGGDPVPGGA
                     APCSFDDMCQLQYTSGTTGKPKGAILSHGNWLSALEAEREVLSLVPGDMYLGIYPMGH
                     IGVSWGIAVLRAGGTWVIMERFSEPEYIRLVKEYRITVLASMPPVIHGLLHAPPGTEE
                     AFSTVRVMISGGGQLLPAVWEAFDRRYRIPVANSYGLSETIVVGSGTATLPGRPGLTR
                     GYRSVGIPVGYTEVRVVDTENPESILPAGEQGEIAVRGPAVAQGYWNREEESRETFLP
                     GGWFLTGDIGYMDGEGVLYITDRKKDMINMSGWKIYPTEVENVILQHPAVEDAAIFGV
                     PDERRGEIPAAAIVVRRGCEPADEEILGFCRERLAGYKVPRKIIRVASLPRVHGWKLL
                     RRTLREQYFR"
     gene            complement(22808..25228)
                     /locus_tag="PK679_04955"
     CDS             complement(22808..25228)
                     /locus_tag="PK679_04955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDC48 family AAA ATPase"
                     /protein_id="HPC55341.1"
                     /translation="MHELHLKVDSAYPGDQGGGKARLDPETMLFLKISPGDIVAVEGK
                     RRTVAKVWRSLVEDWNQNKVRIDNFTRMNAGVSIGDTVKISRIQDEVEAKRVVLAPPE
                     DLPRNVSINITPHVLNSLIDFPVVKNDIVPLSSGLPFLQTQFIPFKVVEIEPEEAVII
                     TKNTHVEFSEKPAPGVEGAKRISYEDIGGLKDELQRVREMIELPMRHPELFQRLGIEP
                     PKGVLLFGPPGTGKTLIAKAVASESGAHFISIAGPEVISKYYGESEQKLREIFDEAEQ
                     NAPSIIFIDELDSITPRREEVTGEVERRVVAQLLTMMDGLEERGQVVVIGATNRVDAI
                     DPALRRPGRFDREIEIGVPTEPDRVEILKIHTRGMPLAPDVNLDTLAQQTHGFVGADL
                     AALAREAGIRALRRYLPEIDLEEEEIPSEVLETMVVTGSDFRDALRDVSPSAMREVML
                     EVSHVTWDDVGGLEEAKQEIREAVEFPLTQRERYDELGIRPPRGVLLYGPPGTGKTLI
                     AKAVANESGANFIAIRGPQLLSKWVGESERAVREIFKKARQVAPAIIFFDELDALAPT
                     RGSDVGTHVMESVLNQILTEIDGLEELKDVVVLGATNQPLLVDPALLRPGRFDRLVFI
                     GEPGLADRKKILAIHLRGMPVEGSALLDVIGHLQPLGEEGIDAVCDALGKDRDVTPED
                     ILSAAANVKASEKPPLSRPGCRRYLVEQMAARHLRLADPVVEALVTEIASRTEGYVGS
                     DLEALCREAGVFAMREGVPAVAKRHFEASLSKVHPTMNPHLREYYERIRQTFKGGLPR
                     EVQLPEYQ"
     gene            25268..26455
                     /gene="larC"
                     /locus_tag="PK679_04960"
     CDS             25268..26455
                     /gene="larC"
                     /locus_tag="PK679_04960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HPC55342.1"
                     /translation="MRVLFFDPVHGAAGDMVCGALLDLGADAGLVTAAMRSVVGEPSV
                     SVVTRAGIRAVSVDTRATPAARTLDEVISRVREADAPESAIGMACRVFSRIAAAEEEV
                     HGRSAHFHEVGADDAIAEVIGACTALCSLGVDAVATAPVPVGGGTVETHHGTYPVPAP
                     ATLAILKRSGIPVIYGPPGEGELCTPTGAALLAEMVTLPEKARLCGRVVAAGYGAGDR
                     DFPSVPNVFRAVLLEDLPGARDDSVDVLETNVDDATAEVIAACSETLMAAGARDVCII
                     PCTMKKGRPGWLVRVVCLPGDGERLSAILARETGTLGIRCIGSVHRFVAGREVTEVSI
                     TLNGETYQVPVKCAVFDGSVYSCKAEFSRVREVAQRASVPAREVARMAEEVAWKRVRR
                     KSP"
     gene            26452..27141
                     /gene="radB"
                     /locus_tag="PK679_04965"
     CDS             26452..27141
                     /gene="radB"
                     /locus_tag="PK679_04965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair and recombination protein RadB"
                     /protein_id="HPC55343.1"
                     /translation="MSEKFQKTGSDALDDLIGGGLCPGILTQVYGEPSSGKSTICVMA
                     SVACLRSGKRVLFLDSEGFSAERFRQVAGTDALELAQNLFLFEPEDFSQQTAMLRNLD
                     SLLQEGAGLLVVDSLTGLYRSQLERGRDAMQRLTGQVLLLLGYARRYGIPVLVSNQVY
                     MDPEKNTFVGLGGTALEHLSKVIVRLERKNHVRRATLVKHRSKPPGSYFDFEITNEGI
                     RVCTGEVAGKD"
     gene            complement(27258..28076)
                     /gene="dapF"
                     /locus_tag="PK679_04970"
     CDS             complement(27258..28076)
                     /gene="dapF"
                     /locus_tag="PK679_04970"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HPC55344.1"
                     /translation="MEIHFTKLHGNGNDFILIDEYERTVIPDEMKAEFAMLFCDRRFG
                     IGGDGVLFLSRSDKADLKMRLFQPDGSEAEMCGNGIRCLAKYAYDQGNIRKSCTVETL
                     AGIIPVECGYRDDTFFARIRMPDPKFGRADIPATGEGEYREQIGGVDVYAVNTGVPHA
                     VVFVGDPDSVDVNALAPPIRHHPTFPKGANVNFVGRSGKNALRIRTFERGIEGETLSC
                     GTGATAAAAVAHHLGYVDSPVEVETPGGPLSIILSDGTWMEGPATTVFSGTITF"
     gene            complement(28151..29116)
                     /locus_tag="PK679_04975"
     CDS             complement(28151..29116)
                     /locus_tag="PK679_04975"
                     /EC_number="5.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0046033 - AMP metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphate isomerase"
                     /protein_id="HPC55345.1"
                     /translation="MLADTAEKIKSMEVRGAGRIAREAVKALHDHAISVQAETVAEFR
                     ERMEEAASLLISTRPTAVSLPNAVHSVMATLRRDYPSVGSARGEFQRACDTFITGSLL
                     AVKKIGEIGARHIRDGDVIMTHCNSEAALACMLEAWRIGRDFSVFATEVRPRNQGLLT
                     IRTLEEAGIPTNFIVDSAARYFMNEVDLVIVGADAISVNGAVVNKIGTAQIALAAHEA
                     RTRVMVAAETYKFAPRTILGEFIRIEERDPSEVLPPDIAGQFRHVRVRNPAFDVTPAE
                     YVDLIVTEAGAIPPQMAYIIIRDILGWDIGDFMQGVPVNGGEEKE"
     gene            29185..30027
                     /locus_tag="PK679_04980"
     CDS             29185..30027
                     /locus_tag="PK679_04980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HPC55346.1"
                     /translation="MSVAVVFDSAGTLLHTYRVAKNVLTGELFPGIETVSLTFASPDR
                     VLVVVHVHSREVIAAPDNLPFSTYLRNNNVGFGISCTRKVIAADEVAEALYNSPHGTV
                     ADLKDCIRNVWQVCRKESVVTMNSGVIVNMSLSGIEFMVTTGGRPFDGARDAISELHR
                     MGVPTFIASGDRVAKLEKMADYLGVPRDRVFGVATPTVKARIVEDLKADYDCVVMVGD
                     GINDLCAMKTADVAILSEEQSGEKHPELYEAADHVVTSVREVVGIVRGLVDSGGTRRV
                     DCVR"
     gene            30075..31694
                     /gene="atwA"
                     /locus_tag="PK679_04985"
     CDS             30075..31694
                     /gene="atwA"
                     /locus_tag="PK679_04985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl coenzyme M reductase system, component
                     A2"
                     /protein_id="HPC55347.1"
                     /translation="MNPLITVKNLCMDFDGKKVLKNISFEIGEGEVLGIIGRSGAGKT
                     VLMHLLRGVEQHPTSGQIIYHVAVCDSCPYIGVGSMAGKPCPSCGSVLRAQDIDLWNE
                     KDEDLRRRLMRRTAIMFQRTFALYGNDRVIENVLHALDDIDYPQDKAINRAADLLDQV
                     RLSHRMMHIARDLSGGEKQRVVLARQLAKDPFLLFADEPTGTLDPETADLVHRMLTEA
                     CRRNHMGMVVTSHFSQVIKSVADRAMLLVDGNIAMLGSPDEVITKFMADLSDTETFEV
                     PEFGREILIARDVFKRYISVDRGVVRAVNGVTFEVYEREIFGIIGKSGAGKTTLSRIM
                     AGIIEPTAGEMIIRIGEDAVDMTKPGIENRGRAKGYIGLLHQEYDLYPHRTVLDNLTD
                     AIGLEFPKELAMRKAVITLKMAGFSEEKSREILDRLPGQLSEGERHRVALAQVLIREP
                     RMVILDEPTGTMDPLTKVDVKHSIMHARDEMDETFIVVSHDIDFVRDICDRLALMRGG
                     KIVAIGRTADVLATLTAEEREVMGTATSSSN"
     gene            31702..33231
                     /locus_tag="PK679_04990"
     CDS             31702..33231
                     /locus_tag="PK679_04990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 3 protein"
                     /protein_id="HPC55348.1"
                     /translation="MISLLVDGEKRLAREGETLGDILPGWDRSSYVAVIRPGARESSV
                     TGSMRLISSAGEVVVDLLPAGRELFQSPDLRLPLPVHWHDRYAAAFGPFPSGFVPARK
                     PHLYERGDLILGCGGYDPNRSYLIFSRIRHTADHGAALEGGVIGRVVSGRGLIDRWTS
                     GDRLMEAFPVVNWADTSRSFTTNDASLPLEDGMEIVTHVRITAHGYTNGTVQSTEAAD
                     TVEHMLLALANDRFVVGRASSTYIQDGRMAGTEVPFEVKSPRREGFVTVRTRGKSTGS
                     LYIYTRDIPSSSSHTLVGQVTHGIELARLARENESFRVSVEPPRFDLIGLFLQEAEEI
                     ASNRGISVSAKGKGNELVVVDQDPGTTLESLDAGSVVLETVPLEKIIDITLDDAHAPD
                     SCEIFRKLTGLHRHRVGRIPFFFHFEDVFLFKPAIPPGININPENLPADVVLPGTLAM
                     TNDSRKGSGLVGVRITENSEFGPTSEPFEGTNIIGRVIDLEKLHKLKENEIAFIREVS
                     P"
     gene            33228..33686
                     /locus_tag="PK679_04995"
     CDS             33228..33686
                     /locus_tag="PK679_04995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 6 protein"
                     /protein_id="HPC55349.1"
                     /translation="MKAYTPLLTGTVTKYVFVESPEMTPSDLAIRAYEISQGVMIKET
                     CFGLQVTGREEDVNRIIDSLRALDPTHIFVKDRGFPPGDPRRCRANLGGARPGYFGHE
                     FEMGLVRFISRGLSALPSRRPDDIPRPPVPEKKERLDAARLKEIIGSQES"
     gene            33689..34138
                     /locus_tag="PK679_05000"
     CDS             33689..34138
                     /locus_tag="PK679_05000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 5 protein"
                     /protein_id="HPC55350.1"
                     /translation="MANVFIFPTTSLILSDLVARFGHTPLSAAMQIREIVQTPGLESP
                     PLQITPEDPKKGLRWAAVEVPAGVRGRMSLYGPLLDRAEAAIIVNNADFSFGCMGCAR
                     TNELLMFLIRKKGIPVLDLEYPANEEEGVEFVAAIKRFLDSLPGGRA"
     gene            34135..35370
                     /locus_tag="PK679_05005"
     CDS             34135..35370
                     /locus_tag="PK679_05005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 15 protein"
                     /protein_id="HPC55351.1"
                     /translation="MTRVRIAQLSCGPEYSGVQKEINDAAAAVDAEIFFPDLKLADIR
                     QSFSEFGLDVRSPDLKLAIARAKALVEGRVEADAVFIATCFRCAEAAIVRNELRRFIH
                     EKSRLPVVSYSFTERTTSGTLLTRMEALTTIARRRALLAREVQEGITMGVDSGSSTTK
                     AVVMKDNRIIGTGWLPTTGVIESAENAVSEALSAAGISRDEIQAIGTTGYGRFLVGEH
                     LKADLIQEELTVNSKGAVFLADSQHGPSTVIDIGGMDNKAISVQDGIPGTFTMGGICA
                     GASGRFLEMTAKRLGVDITELGPLAMKGLSQKVPMNSYCIVFGTQSLVNALAAGSTPE
                     DVAAAACHSVAEQVFEQQLQEVDIKEPVIMVGGTSLIQGLVRAMGDLLQTPITVPPYS
                     QYIGAVGSALLASGFIRRE"
     gene            35371..35949
                     /locus_tag="PK679_05010"
     CDS             35371..35949
                     /locus_tag="PK679_05010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 17 protein"
                     /protein_id="HPC55352.1"
                     /translation="MEAVEYFEVECPEAAGREYYRKIADVVLLDHNLLRVIRKLHIFI
                     DPKVPIFVATGVTRKLPGIVRVRDFADVNVKDTNVTISIGDEAYLAPLLRILWDKFGK
                     ERVNQPDRFTIVLSVGEGEGDIADLPVYDPSESIYKDLIYVLQVIQPEGFKVRRQYYG
                     GNRFYLVASEDTLPDDIEDLVRQKFALMGVEG"
     gene            35946..36884
                     /locus_tag="PK679_05015"
     CDS             35946..36884
                     /locus_tag="PK679_05015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 7 protein"
                     /protein_id="HPC55353.1"
                     /translation="MTHVPVTYKGGIYRHDEIIDLIEDLGGYIIQKHVIAQEIVLQAL
                     VPREDIELIRRIGKPLTGEVTPSPLVGTEIAVVTPSLEIHHLPHASCDVAEYIRRFGA
                     KTNMVGLARGFGKRIAQLNDEERDIINEHDLAVYLLGDFETCIERKFPVLRRGIDVPI
                     VLCGGPSTEALRRIIDPPVEGYVGGIGRFMHRTKESEEIGKLEEVVGEITRVLDQRRE
                     DLARDPLSISPARLMDIIAENVEEIHEVLSPTPITVQMQGLRVKLPYDTFAPVIRKLV
                     IDEGTTIGDLATVSPSRMRDYILLRIKPFSETNIVL"
     gene            complement(36920..37462)
                     /locus_tag="PK679_05020"
     CDS             complement(36920..37462)
                     /locus_tag="PK679_05020"
                     /inference="COORDINATES: protein motif:HMM:NF038353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FxLYD domain-containing protein"
                     /protein_id="HPC55354.1"
                     /translation="MRRGNTWAVLALTGIMGLMILAAGCLSPDVLLPEQRQGGEIPPT
                     AVPTESTYPSGAGGEPVPGVAQASPDAGGPQHFVATPYGYVLTRPVSGTRLSIIEIKE
                     ETDETGQKYLTGKVKNEEQVTLNHITLQFNLYNANGNLIGNTYASVNSLAPQKTWKFT
                     TQPFPPRDYHHYEMAEIFIA"
     gene            complement(37580..38779)
                     /locus_tag="PK679_05025"
     CDS             complement(37580..38779)
                     /locus_tag="PK679_05025"
                     /inference="COORDINATES: protein motif:HMM:NF015669.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="META domain-containing protein"
                     /protein_id="HPC55355.1"
                     /translation="MRQFIKGEGTVVFVNLEGGFFGIVADDGSRYLPDTLPSSCRAEG
                     TRVSFRGFLRQDVSTIQMWGKPLRIVSIQPLGEEITAEGTIRYVDLEGGFYGIESSDG
                     THYLPLNLPENYRIDGLLIAFSARTSPDTPTIQMWGIPVTILSIRAQSQSGGWTRSAL
                     NGAWTLESIAREGVLTPANRQKEVTAVFDGKGNVSGTSGCNLYSAPCFVDGHTLKIGK
                     VTSTMMYCPDVSRQFLRQETIYYNLLEQAASWEIRDTSLVIRDAQGREILVFGRQAAR
                     EPAPLVEFWRTGGFAGMNDHLAIFSDGTAVLERKEYRSNFTLSRALLESLEADLAALG
                     FETLAPSYRAPPGSADYFTYRITYQGKTVTADDGAVPPALLPLIWTLTRLVSGNGPDD
                     IIPPAFR"
     gene            39261..39728
                     /locus_tag="PK679_05030"
     CDS             39261..39728
                     /locus_tag="PK679_05030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HPC55356.1"
                     /translation="MPTTMATDDLVEFEQTLKEIVTRGGEETAREWMDNIEAEYGRAP
                     LIFKRMAERPEVLISHLLYKGAVTRTSSLDPKYVELISMAVGAALRCQHCTSYHMQAA
                     AKKGATREEILEVILIAGLISNSSVLANAYRIFDEKMARCIPCVNEGIDQQVE"
     gene            complement(39697..41553)
                     /locus_tag="PK679_05035"
     CDS             complement(39697..41553)
                     /locus_tag="PK679_05035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HPC55357.1"
                     /translation="MRKRQPRFLPVSRKEAARLRIDQFDIIIVSGDAYVDHPAFPTAL
                     IGRVLWEEGYSVGIIPQPDWKGRDDFLALGAPRLFFAVAPGNCDSMVNNYTPARKRRS
                     EDVYSPGGKPRRPDRAALVYSDRLHALFPDVPIVLGGIEASLRRFAHYDYWSDRVRQS
                     VLADSPAHLLVFGMGEQQLREIARRLAAGEKMGEMPPIPGTVEKVPLPDLDPERYPGL
                     LEIPSYTAVREDKEAYARAFALHYREQDPLRGRPVMQRHPKCIIVQNPPAPPLPTPVL
                     DAVYKLPFTREAHPAYDQPVPALEPVRFSLTSHRGCFGGCSFCAITHHQGRIVQSRSI
                     ESLVREATRLASLRGFSGVITDVGGPTANMYGMGCARWQTAGACPDKRCSPACPSLSV
                     SHSRQKELLARLRQVPGVRKVFIGSGIRHDLLVADSYSLLPDLCAHHVSGHLKLAPEH
                     VSPHVTDLMGKPRADIFTAFVAAFEKIQEGKKKRQYILPYFMSGHPGCTVADMVALAE
                     FMRDHGFRTEQVQDFTPTPMTASTCMYHTGLDPFSLEPVHVPRGREKAVQRALLQYWE
                     PRNQPLVREGLLMAGRADLIGDGRKCLVPAVSAPGYRKGKGKVTRPAGRSPR"
     gene            complement(41558..42004)
                     /locus_tag="PK679_05040"
     CDS             complement(41558..42004)
                     /locus_tag="PK679_05040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HPC55358.1"
                     /translation="MQCIEGRPGRVFVLRIDHGEDLIRALETCVAEKNIRCGFIQVLG
                     AVRSAHLVTGPEEPVLPPVPHREDIRDGWEIVGIGTISWSDGNPHVHLHTATGRGLRA
                     LTGCMRDAADVYIVVEAVIFEVGGIETGRFPDPLTGLSLPDHVSPD"
     gene            complement(42038..43861)
                     /locus_tag="PK679_05045"
     CDS             complement(42038..43861)
                     /locus_tag="PK679_05045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HPC55359.1"
                     /translation="MALTGEKRDLLVLVAVALAIGAVAIVIAFFVPILLEGDLFIADY
                     RATLQENGTFGEVYTYEVRSGGTYRMLYRYWQDPLSVEPLESPFIRIVDMEIPPGTVG
                     YIRESSGKVTLYRDDNPAYVRFIEDKAERNEVGIYNPGYFPAGTYTVSYTYTLHPPIE
                     YDAKDAHLNLRLVDRHIPYRHLEIRIPARYAQEIFPHPPGLSVSREGEWVRISGNVAA
                     DEVLGIETLFAPADKDSLPGFPVPVDGVRAKTLAANPFYDIFPLYFARVLYGLGFAMV
                     VLTPLLLVFLYRKYGTEREFTVPEYLSFTPDPTMKPWAVNLLFKGDPMTFDEDGYFAT
                     LLDLHRKKMIAIQEKPDGKGVRITVNQKTAPDPYEQRVLDFLQEIGEEGTVDSEALQN
                     TVARARSDTTAERMILRYQKDLLSVTRKSDPRLVARYIVDGRDHIFPLLFVAVALCAV
                     SIIALIVTPQLSSFLLPAVLLFGAMIVQSGIALAFPSTLFGHWKDDRYREKLQWDAFA
                     RFLSDLALIRQYAPADISMWGEWLVYGTALGVGDKVEKAMKDLHVSLPEAGIPLASGL
                     NAAFIPVLAFSPPSRGGSGGGFGGGSFGGGGGFGGGGVGGR"
     gene            complement(43864..44442)
                     /locus_tag="PK679_05050"
     CDS             complement(43864..44442)
                     /locus_tag="PK679_05050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HPC55360.1"
                     /translation="MSMALGDLIPWIIIGILIVIAVGLVLYFVGIYNRFFSLKNSSEA
                     TLGQIRVAMKKRLDMIEQLLGAVKSYAAFERETFEKVTAMRASVGSAGPGDLNQIERE
                     SRSLLGRLFAVAENYPDLKTNSTVMTLMDSVRGVEDEIARQRYTYNNISQQYNTLCDV
                     IPSNIIARILGLSKLQYLEFEEAIQTPPKIAF"
     gene            complement(44616..45578)
                     /locus_tag="PK679_05055"
     CDS             complement(44616..45578)
                     /locus_tag="PK679_05055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HPC55361.1"
                     /translation="MPNLTVAVIGPGGYAGHLGKKGTVSDITFYNQKRDQTTVTYVEP
                     GRYPEKISSLFFAVSMADMALLIVDEINPAFGECVLMLDAAKVEKGVLVLRNYLSPEQ
                     VLPLVKGTVVENYTLEPDDHNHLREMFLEAAGKQPAGAKGLKYGSVPVDHHFPVKGVG
                     TVVLGGVAEGTIRVHDELRVFPTIRVAHVRSIQKHDEDVPEATEGDRVGLALKGIEAG
                     DLDRGFVLSNNPSLTVSGILNGRAELVRYWPGPLREQMVVYLGHWMQFIPARVAYVNN
                     SGDWRRPEVTFRSEKELVFPPGATVLIHHLEGGKLRVVGRIVPR"
BASE COUNT         8524 a        14072 c        14036 g         8859 t
ORIGIN      
        1 cttgtcccgg tccctctttt tgatgatgcc gaggatggtc gcagacgatc ccccggtaag
       61 gagggtgtcc tggtcacggt ccacctggcc cgccccggca atgccgggaa tcaccctgca
      121 cggtcttttg tcagccggtg agagagcccg caatctccct tacggtctcc acgagggcag
      181 agacctcctc ccccgttgta tagcacccaa gcgacgcccg gacggttccc gcgggatgga
      241 gggacgctgc cagcggctgg gcacagtgga acccggaccg gacgcagatg cccctccgcc
      301 ggtcgagttc cgcggcacat gcgtggggat tcattcccgt gacgttgaag gagatgaccg
      361 gcgagccccg ggggctgtag accccgacac cgggcagtgc ggagagcccg tcatgggcca
      421 ggcaggcaag cgtggtctcg tgccggtgga tgttatccac gccgagttcc atgacaagcc
      481 cgatcgctgc gccaagaccg atcacgcccg ggatgttcgg tgtccctgcc tcgaaacggg
      541 cgggcggggg gagcagggag aacccgtcga gcgtaacctc cccgacgatg ccgccaccga
      601 ggatgcatgg cgagaggagg gagaggtcgg atgcatacag gattcccgtt ccctggggac
      661 cgaggagccc cttgtgcccc gggatggcga cgaagtcgaa cttcccggcg tcgaacggga
      721 tgtgcccggc ggactgcgca gcatcgagga ggaccgggac gtcccggtcg tgggcaatgt
      781 ctgcaacctc ctccacaggc tggaccgtcc cgaggacgtt tgtcatgtgc gtgatcgcga
      841 caaggcgcgt cctcttggtc agtgcacccc cgatatcgcc gggatcgacc attccgccat
      901 ggtgggggac aaccacggtg cggacgcccc tcttctccag gttcatccag ggcaggaggt
      961 tggcatggtg ctcgagggct gtcgtgacga cctcgtcgcc cctctcccag gacatcccgt
     1021 tcgcaacaag gttgatcgcc tctgtcgtgt tccggacaaa gacgagcgtg tctgacggaa
     1081 cacccagaaa acgggccagc acgtcccggg tccgctcgta ctcctccgtc gtccggcgtg
     1141 ccagccggtg ggatcccctg ccgtggtttg cggcatactc gtaaaaataa gcgcacatgg
     1201 cctcgaccgc cctccgcggt gtctggctgg tcgaggccga gtcgaggtat atgcaccttt
     1261 caaggaccgg gaactcctcc ctcaggcgtg caagatcgta catcgggagg aattatcgtc
     1321 ctgtctgacc ttgagaattg ccgttcggac gcagggtcac atgaagtcgg caagtccctt
     1381 ctgctcggac ttctcctgcc cgaacgtcga ctctattgcc atgtcgagga cggcaaccct
     1441 ctggcgggta tagtccgaga tcctgtagcg ggtacagata tcgcgggaga cttcgaggta
     1501 cttcttcaca gagccctcgt gcaccgtcgg gatgatgtta ccgccgcacc gggtgcactt
     1561 cccggcaagg ggcatccgcc tgtaactcgc gttgcacctg gtgcaccgga acttctgcct
     1621 ggagtaggcc gagaggttgc ccatcaggtc acggatgaag tgggttgtga gcaccctctc
     1681 ggccacgtca tgctcgtcga cagcccggat cttctccgca aggtcgagtt ccttctgcag
     1741 cttgtcgatc atcgacttct gctgggtgta catcgactcg atcggccctg ccgagatatc
     1801 cgtcgtgtcg tgggagaagg aaaacccctc catctgggcg ggcgtcccga gcctccggcc
     1861 caccctgtcg acgagtccct ccacctcccg gggatgggca taccgcaggg ccgcgaggta
     1921 gaactcgagc gggtagccgg acccgacatc gatgttgtgg ctctccttgt ctatctccgc
     1981 agggtcgatc cgcgtcgtga ggaccagcgg tgcatccatc gtcccgcccc tcgtctccgg
     2041 gaggaaagac cgggaaaagt tgatcagccc gtcgaggagg agcatgatgc agtcctcgtc
     2101 cccgtcgcac tgccccgtga agatgccgtt tgcacagacc gtgtgctcgt ccgtgaccgt
     2161 gaggcagaag acccggtcgt cagggcaggg gatgacgtcc cgccgggcaa tgtggtcggc
     2221 aaggacgttc atcccgacca tcaccggcac ggcatccccc tctttgacct cgacggcccg
     2281 gatcttgcgc aggaaacaga cgtcccagag gagcatcgcg tggtcggggg tgaccacgat
     2341 ggatcgcccc cctcttgtct cgaaccggat cagggctgcg ggagcccggt ggatcgagac
     2401 agacgtgacc cgccggaggt gaggttttcc ctcggtgtcc acggtccgga cgaggagcgt
     2461 tgactgggga tcggagtagt acgtgccgag cctgtctatc ccgggctgcg agaggtcgaa
     2521 gttctccgca acgatctgcc ggatcggttt cgtgctccat tcttttccgt cgaatgtctc
     2581 gatcagggta tccccgtgga aacagttcct ccgcttggcc gcgtggaaga acgggtgggc
     2641 gtacccgacg ttcgcccggg agaaccccac gatccgggcg aggacgccgg cactcgtgtg
     2701 gggcgcaagc ccgatgacga ggtggccgag gaggtcctcc cgcgagctga ccctgtagaa
     2761 gggggaaagg ccgtagcact tctcgaggag ctcatcgatg aactgggcga cccggaccat
     2821 gtacccggca caggagtcgg agacgaggat gtcctgggga cgcagttcga ccacctgcag
     2881 gggtgacgtg aggggttttc catcgatatc cgcatcgtac cccagttctc tcagcttgtc
     2941 gggagacacg ccgatttcgg cgggccggat gtgggttaag ggcaggtcaa tcatgtcaaa
     3001 gcggacggtg ccgtccttga agacgaagat atcacgggcc gcccggagga tgcccttctc
     3061 gattggctcg accgtctttt cccgcgatat cagccctcgg acacccttca cgagggtgat
     3121 ggcgttctcg cggaggccca gtctctccac ggctgccatg tactcctgcc tgacgttgag
     3181 tgtcgtcgtc gccgagcagg tggcagggac gtggcaggca gggcaggtat cgctcccgat
     3241 ctcccgcctg caccggggac acgtgtacac cggctccgtg tggctgccgc aggcacacct
     3301 gttccggaac gtctcggccc cgcaggaggg acagcggcgt ctccccgtct cgatggtgat
     3361 cacgccgccg tccatgttgg gctggggtgc gtgggcctgt gcttcctgga acgaccgcct
     3421 gttcccccct gcgtcgccga gggggaagag accgtgggga ggggggttca tcttccgggg
     3481 acgtgacttg cccggccgcc ccatgcggcc gccaatccgc gtcccggcac gggaccgcat
     3541 ggggaggccc gagaggtggc tgacgagtgc gagcgtgtca ctgccgccgg gcacactgtc
     3601 ccacgccggg cgtctcttca gtttcaggtc gaggccgagg cacgcgagga agacgaggta
     3661 ctcgctgatg catatctggc cctccctcac gcggtggggg aggaggatct cctcgaggag
     3721 gtacttgatc cgggggtccg gcgggaggac gagaatgccg tggcgaattt cacccttctc
     3781 cgagacgtaa tcggcgattt cacgcacctc ggcgggcgag atatcgtccc agaggaaggt
     3841 gaaatcgggg tggagaaatg ccccctcgaa acactgggcg atcgcctctt cctcggtctt
     3901 aggccgctcc tttcccccct cctggcacca ccactcgtgg cagtaggcag gcgggacgag
     3961 gacgtggttg ttctcgagga attcgccgta cccgatgagg atctcgccga cgtcgaggat
     4021 gcggtcgacc tcgtccttca gcctgaccgc aacctcggcg tcgtcgatgc ggaggacatc
     4081 gccgttcttc aaccggaccg tcggcccctc tatcgtgtcc accgggacga tcccggcagc
     4141 cttccccggg cgctcgatct tcatctgggt cccgaccgcg aggtagtcgc cgaggatgtg
     4201 catcgtcgcc ggggaaaggc ctgctgcggc aaaccccgtg ttccgcgaac gcccgtaccg
     4261 gagccggaac ccccccttcc tcatcgggta ggcaaagacc gggcgtccgc cgatcaggtc
     4321 gcggaggtac ttgtcccgtg gcgcaatcgc tcctccattc tccccttccc ccggctttgc
     4381 cacgcccctg atcagctcct cgagccagtc ccagccatcc atcgagaggg cccggacgta
     4441 ccggaggacc ttgggggcct tgagggcgag accctcggcg aggacgaggg ccatcccgcc
     4501 gcgcaccgcg ttcgtttcga cccgctcgag gttccggtac ccgctcacct cgtcctgttc
     4561 agtcccctcc ccgtcgatgc agaccgggca gttctggacg atgaggcgaa tctcgtggtc
     4621 ggacgggagg tactggaggt tcatgatgga gttgtactgg cggatctcct cgatgtagcg
     4681 ttccacctcc tcgggccggg gaatgtacct gttcatcccg agttccctcc ggacgaaatc
     4741 gccgacgagg acggagagcg cctgcgcagt gccgcccgca ctcctgatgg gtcctgcgta
     4801 gtagattttg aggtactcgg agccgtcgtc gttttttccc gttcccacct tcgcgatccc
     4861 ctccgtcggg gcggccacca cgccttccgt gaggattgcc atcgccgtcc ggatggcatg
     4921 gtcgagcact tcctcgcggc tctgctcgcc gaaacgccgc tggacaaaat caagcccgat
     4981 gcggagtgca gcctcctcgc gggacatctg gccctcgagt tccctgatcc gggaagcaat
     5041 tcccggtata ccgagcagtg cctcgacccg gtctgcaagg tcgcttgcga tcgggatctc
     5101 gaccccggtc cgcgggtcca ggccgagtgc ccgggccttt cccgcgacct ccattgcgcg
     5161 cgagaggcct tcctcgaggc cggcaaggta cttctccatt gcaggggagc agtggatcat
     5221 caccttctct cttgccaccg ggagacttat cccttcggtt tttcccggac gggcagatcg
     5281 tccctgtccc gggagatacg aaaaagcgga aaaattttgg aggaggggaa attaattgcg
     5341 tcgaccttcc tgtcacccgg gcccggacat gagggcatcg atcccctctt cgcccatctg
     5401 ccagagtatc attgccgcgt actggcgcat gtccggatcg gcggagccga gcgcggcccg
     5461 gagagcggga accgcggctt tcccgacgcg gcacagggcc tgcgcaaaga acccgcgggc
     5521 agaggggtct ttcgtggaga gggctgcgat gagaggccgc acggcaggcc cgccgatgtg
     5581 gccgagggcg gcggctgcat accgccggaa gcggacgtca ctgttcttcc cgatggcttc
     5641 gatcagggga tcgatacccg gcgggcctat ccgggcaagg gcgacggctg cataccagcg
     5701 ggcatcgtcg ttgtcagtct ctgccatgaa ccggacaagt gcgggaaccg cagtcccgcc
     5761 tgccgctgcg agggtcttta cggcacttct cctcgcggca aggtcgccct gcgcgagcac
     5821 ccggacctgc tccgcgatct cctcttccct caccggatat cgcccccgcc gtgcgcatgg
     5881 gacacctcga tccttgcccc cggcgcgatt gtcacgaccc tctggggata gggtatctcg
     5941 attcccgcct cctcgagcgc cttcttgatc gtccagagca tctcggtcct caccgaccac
     6001 cagacgcggg acggcgccca tatgaacacc ctgatgatca cggccgactc ggcgaggctg
     6061 tccacgaaga cgctcggggc cgggtgtgcg agcacgaagg ggtggtcctc gagcagcgac
     6121 cggatgatcc ggatggccgt ctccgcatcg gaccggtaac tgatgccgat cgagtactcg
     6181 aacctccttg cgacgttggc aacgtaattg gttatttccg aggtgaatac cttctcgttc
     6241 gggacacgga catagacccc ctcgtacgtc ttgatgatcg tcgagaggac ccggatctgg
     6301 tcgacggtcc cgctcacttc cccgatggtg acgttgtccc ctggtttcat cgggcgttcc
     6361 gcgatgatga agagcccgga cccgaagttc gagacgatcc tctgccccgc gaaggccgcg
     6421 acaaggccga tcgtcccccc gaccaccacc atgtcagcga tgttgatatc gaagcggggg
     6481 agcgcggcgt acaccccgac gatgatgatg gccgcctgga tgaccttgac gagcttgtcg
     6541 agctcgacgg gatcgacccg gtcgctgaat gcctttttga ggtagattgc gacgatccgg
     6601 gagataatgt aaaccacgaa gacagctatg gcaaagacga ggagatcgag gagggtgacc
     6661 gtgccaatga caggtattga gagcgattca aagaccatgg cccatctcag tcccccaccc
     6721 cgtattccat caggtaactt ggtttttcgg gaacaagact cttttttgtc gggaaaatcc
     6781 ggatggcctc ctccatgccc tcccgtggcg gtgtcctggt gacccacgtc tcgcccagaa
     6841 tacgggagta gaccatcatc tctgcggaca tggcggcatg ggggccatag aagatccgca
     6901 gggagggact ctcaaagact gcccgggaca cccataccca gtcctttccc gtgttcctga
     6961 ttgcaagtgc aaggatgccc tcctgcaggg ggtccaccgg gggaggttcg tgactgaccc
     7021 ccgtctccac gtgccgcgtg atcacgccct tttccggggt cccgtacagc gagtacttgg
     7081 gcttagcgag ggagaatacg tcgatgaggg tataactgcc ttccgagccg gaaaagacac
     7141 ctatctcgac ggggaacgtg agaaagacgg tcacctcgga gaggggttct atcgcgatcg
     7201 gggtaaaatg gaactcgatt gtattcgtga cctcctgggg aaggttgacg ggttccaccg
     7261 ggttgatggt gatcgttccg ccggagaacc cgagcctcct ttccacgcgg ccggacggcg
     7321 ctaccctctc gtagagggta aactgtcctt ccgtccttgt ctccaccgtt atcccgctct
     7381 ccccgagccg gaacgggatc ccgtacctcc cgaacacgga gaagagatcg ggtctccggg
     7441 aacatatacc tgacctgctg ccggtgccac tcacggcccg gcaggtctct ccccgggccc
     7501 ttcgtgccgt tcccctgcat cgatgacgga aaggatgaac tcgcgcgatt tcctgtctgc
     7561 cccggacagg aggggaacaa accccttcag cagcttttgg ttcgggatat ccctgatcgc
     7621 ctggaacacc cctgcccttt ctgccaccgg ggcggcggac aggtagagga tgatgtgcct
     7681 gtacccttcc ccgccgtgct gcatcagggc ctcgagggct gccgaccgga cagtcgcgtc
     7741 cgggtcaccg agtgcccgcg tcaggtcgtc gagggcggca gggtcgcgta tctttcgaag
     7801 cgcgagcact gcacccttcc ggacgggttg ggggccgttt gcaagggcaa ggcggaggag
     7861 cggcgccgcc cttgtcccaa attccccaag ggcgtaagcg gccctgctct ggacaaaacg
     7921 gtccgaatcc ccgaggagct cgatgagggg ggagatggca cggtcatccc cgatctcgcc
     7981 gagcgcgatc gctgctttcc accgcacgtc ctcgtcgggg tggtggagtg caccgatgag
     8041 ggggacgact gccggttccc cgatccgggc gagggcttcc gcagctttcc acctcacccc
     8101 ggaatacctg tcagcggtca ggacttccat caggggtgca acggccgagg gttcgcgcag
     8161 ctcgcccaat gcttcggccg ctgcatactg gacggccgga tccttgtggc caagggcccg
     8221 gacgaggccc ggaacatccc tctccacgcg catccggtcc acgttgggag ggccaatgtg
     8281 ccggaggagg gcatctcccc gcgggaacgc tcccctccgg gcagtcgccg tccgggcttc
     8341 cgcatccccc gtgccggcca ttgcctcgcg atgcttcctg cgcgccgaat cggagacaag
     8401 accgataacg agcgagacaa ggacgaacat cccggcccgg atcgaggagt cgggaccgat
     8461 tgtcccggaa aggagggccg tgtctgcaag gtagagggcc gagaggaaga gactgacggg
     8521 aagtcccctg atacccatcc atgctgccgc gaggacgatg ggaacgtaga agaagtgcga
     8581 atagaccgtt tccatgccaa ggccaacgtg cacgacgagt tcgaggatga ctgatacggc
     8641 gacgagaaac acgatgatgg cgatcttcgg gcggtcaagt ccttcgcggg ccgggcggag
     8701 aaggttcatc gagtcagggt ggcacaggcc ctctgataaa tcctgcggaa cagaaaagag
     8761 aaccctgccg tcattccagg cgggtaaaga ccgggtgtgc ttttcaacct cccggaggtc
     8821 cgggtttgtc aatctcaaaa tgccggtttt ttcggacgcg atgcgtgata ctgccgccgc
     8881 gacggtgcct tgagcggtgg cgggcgacgg gtccctgcac gcggttctta ccacccatcg
     8941 gggagagccg cgatcccaaa aaaaagagtc cgggaagtag ggggcggggg tcaccggttc
     9001 ttcccggaac gcccggttgt ttctcctgtc gcaannnnnn nnnnnnnnnn nnnnnnnnnn
     9061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9121 nnnnnnnnnn nnnngggggc gggggtcacc ggttcttccc ggaacgcccg gttgtttctc
     9181 ctgtcgcaac cccgatgcac tcttccgttg tcccgaggcg caccgctgcc ccgcacatgt
     9241 ccggcacgta ggagaacgcc ttgcccgagt tcaccatgat cgcccggaac cgctccatcg
     9301 cgggggagac gaccatgcac gtgtctgcaa acacgcgggc accgctcgcc tcgataacgg
     9361 caacatcgtc gcggtgcctc tcgatgactc cccgggcggc aaacacgtaa caggggatct
     9421 tcgtcacttt tccttccaaa agacgtgcaa tcgtgccgag ttcctgcgga gaacagtggg
     9481 gacagcccag ggcaactgcc tcgacgggga tctcctccat gatcgtctct atctcctttc
     9541 cctcgacggt gatgacctcg aggtctccgg ttgaaaagga gaagatacgg gcctcggggg
     9601 tgatgccggc cacgtgaaag agtgcgactg caccggatgc tgccattgcc gcgccgagtg
     9661 ccttcaggtt gtccctgcgg ggagagatcc cctcgaagag gggtatccta cccccgacga
     9721 gttttcccac gtggtacccg agagccccga aaagggcagg gtcggagagc gacgcgcctc
     9781 cctccacccg cacaacgatc tcgggacggc gttgggaaac gaggtgcagg ccgtactcgg
     9841 gcgtcctccc cattatcgcg gcggcaaggg ctcccggtcc cccctcccgg ttcgtccgtg
     9901 caccgatcac cgagtttgcg tacacaacgg ctgatgattc cgaccaggcc aggtggtcgc
     9961 cgtactgcgt cacgtagagg taatacggcg tgcaggtgca ctcgagggcc aggccaagct
    10021 tccggtaggc agcgatgacc tcttcctggg cgcgtgcaaa cccggggtcg atacccatct
    10081 cctgccaccg ctccctgtcc atccccacgg ggttgaggac ggtcgggaca gcgaccctcg
    10141 cgtccagctg ctgcagccat tcgaggccgt acctcccgat cgtcttgaag gacgccccgc
    10201 tcacctgggc actccggatg ggaatgagac gctctgcccc gtagaccttc ccgagagcga
    10261 tgaggatttc gagcatccgg gcccgggtct caccctgctc cccggcaagg atggcctcct
    10321 cctcggacga tagtctcatt ctccccctta ccagcccgca cgcgtaaact cgtgctcgtg
    10381 gccaaggacc attgtcgcgt ccacgcccac cttcacgttc gtcccgtcag ccatccggca
    10441 cgggtcaagg gacgacccgc gggcaccggg aatgatgagg atgtcccggt ctcccctcac
    10501 gcgcgttgcg atggcatact cgacctcggc agggtcggcc gggtcgatgt cctcgtccac
    10561 cacgacgacg tgcttgaggg acgtgtgtgc cgcgagggcc gccaggatcg cgttcttcgc
    10621 gtcgccctgc gtgctcttgc ggatctggat gaccgcgtgg aagtaaccgc atccccccgt
    10681 cgtgaggaca acgttcctga cggtcgtcac ggcagagacc gcccggaaga tgacgggttc
    10741 gtacggcacc cccatcagga tgcggtgctc gtggcctccc gggaggatgc tgtggtagat
    10801 cgcgtccggc cgggcataca tgcccgtgaa ccggatgacc ggctgcatcc tgacgctgtc
    10861 gtacgtgccc gtgatgtcca cgaaaggccc ttcctctgct gtctcggccc cgatgaaccc
    10921 ttcgagcacg atttctgcct cggggacaca gaccccgttc cggcaccggc ggaccctcac
    10981 ttccccgccc atgagttcgg cagcaaaggc tagttccctg cccttcggga cgcgtgtgca
    11041 gcttgcaaac gtgactgcag ggtggactcc gatggcaact gccaccggca gcacgtcacc
    11101 ggccgcgagg gcttccctgt gcatggtgaa cgtatgcctg ccctcgacga gccgggctgc
    11161 gaccctgtcc gggccgagga cgagcatccg gtggatcgat gcgttctcga ctcccccgta
    11221 ggcagaaaaa acgatccctg ccgtgatgta ccggcctgca tcgcccggga aaaacttcat
    11281 gacggggagg cgggagaggt cggcctttcc catggggagc gggtcttccc gcacgatcct
    11341 gccctcgtag gaagcccggg ccagggtctc tgcgatcctg ttttcgtcca ctcccagtgc
    11401 gaggccgagt gccttcctcg ttgccgtgag gttcattgcg gcacggccgc cgggaaggtc
    11461 gtggaagagg aggagggagt ccgtccggct cgccatccgg ggtgcaccga actccccttc
    11521 cgggcattcc tcgacatcga tgaccgcccc cttctccctc atcagttcga tgaattcacg
    11581 catggatctc ccgccttcct tccatgcggt aaggtgtgac ctcccgtcag ataaacctgc
    11641 aagccttcgc ggggggaggg gttcctcccg gcgcggggcc gggcagaaag ggcgggtttt
    11701 tcaggtgcgc ggcgggttgt agaaccggta ccggaactgg gcttcttcca gcgcccgggc
    11761 gctctccggg tcgagttccc gccgggctgc ctgcacgatc gcgttgagga tgtttttctc
    11821 tttcaggacg tcgtagtcgc cctcgcgggt ctcgttcaaa aaatcgagga gttcgttgac
    11881 gtgcccgagt acttcgggac cggcaacgag gttgacacgg ttcaggacga acgcgaggtt
    11941 cctcttggcc tgggaaaggg catatgcgtc gccgcccgcg accgtgaggc gggttaccgc
    12001 gcagagaaaa tcgttgtata ccttcagttt ctgcctgttt tgcacgagcc ggagttccct
    12061 gctcttcgcg tagagatatg cacaggaggt gatggcggcg actgccacca cgcctgcaat
    12121 gaccatcgtc cagtattcga tcacactgac ccccgaggac tccttttagg cacttttcgt
    12181 atttgagcat tcttttttcg catcaagacc actccggggt tttccagcct tcatgcccga
    12241 ctgcagggaa ggaggggacg gtcgccatga atggcgcacc cgtggttttc atgccatgtg
    12301 cctctgtccg gggaaagaac cgtgtgatat cttccgtatg ggcacgggga cacctagaag
    12361 aggggttcct gcgtcgtcag gggcctgacg tggagaatgt ccgctgcaat ctccccgacc
    12421 tgttcgcgga actcgggcgg ggtgtacaca ccgagccgcc actgtccccg ccgtgtctcg
    12481 ttcagggtgt ggagcagggg ggacacctcc gagagcggga ctgccatgtg gcggtgtcgc
    12541 acctggacgg agagggacat atcgcccggg aaggggggga tgtccacgag gacgcacgag
    12601 ggggctatcc ccgcctcttc tgcaaccttc ttcccgatct ctttccgcct ctcgaacgag
    12661 gcatacctgg ccatgtgggc cgtgttcacc ctgtcccggc cgatgtagag tgccctcttg
    12721 taaagcctcc tctcgtagat cctgcgggag aggtcgcggg caacaggatc gggcgaggag
    12781 aggagtgcct gcatgcaggc tgaatcgtcg gcccggatga gcgcttcgag tcccctggcc
    12841 gggtccctgg ccacgtgtgc catgatcgcc tcctggaaca tcatctcccc tatcctgctg
    12901 acgtggtgga agtagaccga cgggcgcatg agtgtccggg caatcaggag gctctctgcg
    12961 gcatttatcc cggcatcggc aaggacgagg tgcccgtcca tcacgaacgt gttcctgatc
    13021 agccggtggg catcaatcgt cccgtacagg gcgcccgtgt agtgggcgtc acgcaggagg
    13081 taatccatcc ggtcgacgtc gagttctccg tggataatgc cggagagggg gtgcgtgccc
    13141 tggataaggg aggcaacgtc gcccgcgtcg attcccatgg ccccgagaac ctcccggaca
    13201 tcactccgcc cgaggaggag agagacatcc tggtggtggc gtcccaggta ctctccggcg
    13261 aggggctcga tcgcgtgcga aaaggggccg tgcccgacgt cgtggaggag tgcggccgcc
    13321 ttcacgagcg cctggtccct cgcggcaaga ccgagctgcc gtgccatgac cccggcaagg
    13381 tgcatcgttc caagcgagtg ctcgaaccgg gtatggtggg cgccggggta gacgaggtac
    13441 gagaaaccga gctgccggat gtagcggagt cgctgcagga gcggggagtc aagcagggga
    13501 agaaaggggt cctcgacctc cacgtacccg tggacgggat ccttgatgat ctttgcaccc
    13561 atccggaaga acagtcatct ttcggaacga taaagaatac atcagtatga tcgtcctcct
    13621 ctccgggggc acgggtaccc ccaagctcgt ccagggtatg cgcatggtcg tgccagacag
    13681 cgatatcacc gtcgttgtca ataccgccga agacatctgg atctcgggcg ggttcctctc
    13741 ccccgatatc gacaccctga tctacctctt ttcggggctc cttgacacgg ggacgtggtg
    13801 gggcgtcgcg ggggacacct ttgtcaccca cgacgcgctc cttcgcctgg gcagcgacga
    13861 gtacatcgcc atcggggacc gggacagggc cctgcagatc cgcaggggag agatgctccg
    13921 ggagggactg accctcacgg aggcaacgga agccctctgt tccatcatgg ggatcgatgc
    13981 ccgcatcctt ccgatgaccg acagccccgt ggcaaccctc atccgcacga ccggtcgcac
    14041 catccatttc caggagtact gggtccgtca ccgcgggcag ctccggatcg atgaggtggt
    14101 ccggcagtgg gacggccccg cccgggcaac atcccgtgtc ctctcctcca tccgtgagtc
    14161 agagggcgtg atcatcgggc cgagcaaccc agtcacgagc atcctcccca tcctcgaatg
    14221 cgggggcgtg cgtgacgcgc tccgggaggt gcccgtcgtt gcggtcagtc ccttcatcgg
    14281 ggacactccc gtgagcggcc ctgctgccgc gctcatgaaa gcaaggggct gttcccccga
    14341 ctcggccggg acgtacgccc tttacaggga tttcgtggac ttttttgtgc aggacgtacg
    14401 cgatcccgta tcggtgcccg gcgctatccg cgcagatacg ctgatgaaga cacccctcgt
    14461 tgcacgggat ctctccgtcc ttgccctctc gctcatccgg gaggcacgcg ggcggacccg
    14521 ttctccgtcc gaaaaggaca gatagggttt ttacctggcg gacagacatt cgtggaagga
    14581 gcgggaaata atgagtatct ttcgatctct ccggggagca ctgggaaggg agggggacaa
    14641 gtcccccgac gaggcagaga aggaacgggt ggagagcgtt cgcaacgcgc ttgcatacgg
    14701 ggacatggaa gcgcggtgga acgcgatccg ggccgccggg gaactcgggg acgcattcat
    14761 cgatccgctc atcaacgccc tgaacgatga acactggatc atccgccggg gggcagccca
    14821 gacccttgca aagattggtg cacccgcggt tccgcctctc atcgagatgc tggcctgcga
    14881 ggacgagtcc gtcaggcggg aagtcgtcca ggctttcatc ctcatcgggg atacgtcggt
    14941 cgagtccctg atccgggcgc tctcgcgcga ccagcccgcc atccgggagg gtgctgccca
    15001 gatactcggc gagatgggtg tgcagagcgc agtcggaccg ctcgtggagg ccttgaaaga
    15061 caaagagccc cgcgtccgga agcaggcggc aatcgccctc aagatgatag ggcacccgga
    15121 tgccatatcc cccctgatca ccctcctcgg ggacgagtcg ggatacgtcc gcatcgccgc
    15181 tgccgaggcc ctctgttccc tcggtgaccg ggcaatcggg ccgatgatcg ctgcacttgc
    15241 ccatccccag ccggaactcc gccagagggc cgggctcgcc ctcgcagcga tcggcagccc
    15301 ggcagtggag cccctcatcg cggcactcga ccacgaggac cccctcgtca ggcagggtgc
    15361 tgcaggagtg ctcggcagga taggcgattc gcgcgcagtc ccgggcctcg tccgcctcct
    15421 gggtgacccg gtcaggaatg tccgccagga gtgtgtcaag gctctctcca cgctcgggta
    15481 ccctgccata tccccgctcg tctccgcgtt ccgcgagggt gacatggtca tccggaactg
    15541 cgccatggaa gcgctctggc tcatcggtgg tcccgcggta cgccccctgc tcgacctcct
    15601 cgacgactcc aaccctgacg tgcggaggag gaccgccctc ctcctcggcg agatggggta
    15661 tcccactgcc atcgaggcac tgacaagggt cctcggtgac caggttccgg cagtcaggag
    15721 ggaggcattc gaggccctcg agaagatccg gaaaaagcag cccgaaggga cccctcctct
    15781 gccaaaggct gaaaagggcg ggaatgaacc ggcccggaat tcttcaccca gcgcaaagaa
    15841 ggcctgaaag actctttcct atcctgccgc tgccagtgca aaccggagat cgagagagaa
    15901 atccgggacc tcgatgccct ccacccggac catgtactcc cccggttccc atcccgtggt
    15961 atcgaatcca aaagaccacc ggctgaatgc cgccccttcc tgccgggtca cgggtgccac
    16021 tcccgatacc cctgataccg gcaggcccgc cccctttttc gtggggccga acgcgactgg
    16081 cgtgacctgg acaaggacgt ggtttcccgg ggagaggatc gtctctcccg agattgtcag
    16141 cgtgtcaccc gcccggtaaa cggcaccggg agcgagaggc cgtggagaac gctctgcctc
    16201 cacaggcacc actgctgcca cagtcaccgt ctcctggacc tgaggagaag cggtgggaac
    16261 gggtgttatt cccggtgtcc ctccggggct tcccctgcct tcacctccct gcgtttgcgg
    16321 caccatgcac ccggttgcca cgagaagggt aacgaggagg acgacgaggg cggggcggag
    16381 ggcacaccgt tccataacca gggaatgatg ctccgcggca aagaaccttc tcctcttctc
    16441 ccggccggga cgtcgatatc cataagcctc gaaaagtcct agatgagagg caggttgaac
    16501 catgccacag ggagagaggc aatcgtcccg ggaagaggtc gtccttgcgc tgaatgcaaa
    16561 attccctgtc atgcggaagc tctttggggt caaaaagata gggatattcg ggtcccttgc
    16621 ccgtggcgag gacaggcccg ggagcgatgc ggacatcgag gtcgagttcg agccgggaat
    16681 ggatacgtat gcaaactaca tcgggctcgc cctgtacctc gaggaactcc tcgggcgaag
    16741 ggttgacctc gtcctctcgc gcgtccttgc gtcgtacctg cgacccgaac tcggggccat
    16801 gcatgccgca atcagcaggg acaaggtcta cctcgcccgg atcctcgacg agatcgcgtt
    16861 tctctcccac cggacacggg ggatttcagc ccgtgacttc ctcaaagacg agaccctccg
    16921 gcgggccgtc gcccggagcc tcggggtcat cggggagtcg gccgaaaggg tatcggagca
    16981 gacccggaaa gataccccga aaatcccgtg gaaggaactg gagggtctgc ggtctcacct
    17041 cctgcacccc tacttctcga tggactggtc actcgtctgg aacgtgctca acgtctacct
    17101 ccccacggtc gaaccgctca tccgcgcagc ccactcgcgg atagcctgag tgcattcccg
    17161 cccggccggt gcaggggaac gggtccgatc cggtatcgtt taataagcag cagcgacgaa
    17221 cttttttcat aatcgctcag ccggtccctg caccggcggg gctttaacca ctttccatga
    17281 tccactcgta caacctgtcc ccggtcctgc gcgaactcct ggagatgacc gagagcatgc
    17341 tcgggataga aatccagctc gtcaggagga cggatgtccc gccccagggt ctcctcatcg
    17401 acgagttcac gtacgggacg gggaaaaacg tcatcgcatt ctccagtgca ctcctcggga
    17461 cactcaagga ctacacgatc tgccgcaact gcatcgagct ccttgcccgg ggctgtgctg
    17521 cccgccgcgg caaccacaag gtgctctcgt tttcgaagga aagtgccctg gaggggtgcc
    17581 gccagatcta ccttgacatc ctcaaggacg agggtacccg gaacctgccc gtctggcaga
    17641 agaagcagct cgtgttcctc ctcttcatgc tgctccacga ggtcttctcg gagatgcccc
    17701 tgaaactgct ggcagatctt gtcatctcgc accgcttttc actgctgcgc aatgcacagg
    17761 tgtattcact tctcaaggag agcatgaggg acatgcatga ccttgtccct gtcaaggact
    17821 ttctccccca gcgctattat gtcgtgcaca acgcggtcta ctatgcacgg gacatggtcc
    17881 ttgcctatac cctctccgaa tacaagctca accctgtcat caatatcccc gagctccagc
    17941 ggttcaagaa cctcgacatg aaggagatga tgacgcacag gtggagcagg tcaccctggt
    18001 accacacgaa ggtcgtcggc gatgccctct cgaacatgct caagcggacc atcgagatgg
    18061 acttttccag ggaattctcg atggactact tctacgaact ttatgtgctc tcaaccgaga
    18121 tacccgcccg ctggtgggtg atgatgggca tgcaggactg gttcctctgg gattcgccgg
    18181 aagcgagaag agaggtcctt gcctcgcagg ctgccatcga aaagttcgtc agggaagaga
    18241 tcttcgggcc cgactgacgg gatgaagggg cccccttttc ggaaagacag attatcccaa
    18301 aaccaccata ggtaatggat ttcacatgcg gatacctgta agggaggtca ctcccggatg
    18361 cgaaacggct gagatctgtg gttttgttca cgaggtgcgt gacctggggg gtcttgcctt
    18421 cctcctcgtc agggaccgca ccggtatcat ccaggtgacc gtgcccaaga agaaggtcgc
    18481 tccccacatc atcgatgcgg tcagggatgt ctcccgcgag tcggtggtcc gggtgaaagg
    18541 gaccgtcagg gccatcgaca aggcaccggg cgggagagag atcatccccg aggtcttcga
    18601 ggtcatcagc aaaagcgagt ctcccctccc cctcgatgtc gccgagaagg tcccggcgga
    18661 gctcgacacg cgccttgact cgcggttcct cgacgcccgc aggccgcgtg tcgcagcagt
    18721 gttccatatc cggagtgcgg tcgcacaggc tgtgcacgaa tacctttttt ccgccggttt
    18781 cgtgaacatc acgaccccta aaatcgttgc cgcagccacg gagggcggga ctgaactctt
    18841 tccgatcgca tatttcgaga aagaggcgtt cctcaaccag agcccccagc tctacaagca
    18901 gatgatgatc ggtgcaggat tcgaaaaggt gttcgagatc gggccgatat tccgggcaga
    18961 ggagcacaac acgaccaagc acctcaacga ggcgacgtcc atagacctgg agatggcctt
    19021 tgccgaccag aacaccgtga tggagatcct cgaggacctc atcgtctctg tctacaggaa
    19081 ggtggagaag gactgcggtc ccttcctcga agcaatggaa ctcgacgggt tttctgtccc
    19141 gaagacaccg ttcccccggc tcccctacgc ggaggcgata gagattgccg ggaagaagac
    19201 ggacgagccc atccggtacg gggacgatat cgggactgcc gcagagaaag caatcggaga
    19261 ggagatgggc ggccattact tcatcgtgga ctggcccacc gcgatcaagc cctactacgc
    19321 gatgccctac gaggacgacc cctcgatctg ccgtgccttt gacctgatgc acccccggat
    19381 ggagctctcc tcgggtgcac agcgcgtcca ccagtacgac ctccttgttg cgcagatcag
    19441 ggagaaggga ctcaaccccg agagcttttc gttctacctg accccgttcc ggtacgggat
    19501 gccgccccac gcgggatggg ggcttgggat ggagcggctc gtcatgacga tgctcggtct
    19561 ccccaacatc cgcgaagcag tcctcttccc ccgtgaccgg cacaggctcg tcccatgacc
    19621 ataccggacc tcttcgctgc cctccccgtc ctccccacga ccgtcgtcgg gagctttccg
    19681 gtcgatacgg gccggggtct cccgggactc ctgtttccgc tccggcacgc ggtccaaaaa
    19741 gctgttgaat cccaggtcag ggcgggaatc gacatcatct cggacggcca ggtcaggggt
    19801 gacatgatcc gtgcgttctc ctcccgttta cccgggattc gcgggcagga cgtggtaagc
    19861 accgtcctgc ctgcatcggg ttccatcacg gttgccgata cccgctatgc cctctcgcgc
    19921 caccggttcg tcaagggcat cctcacgggc ccgacgaccc tctctttcgg cctccatatc
    19981 gcaactcccg tctacaggga cagggcggat ctcgcgatgg acctggcacg ggcgcttgca
    20041 gccgaggcta aggcactcga aagtgcaggg gtctgcatgc tccaggtcga tgagcctgtt
    20101 ctctcgacgg gtgccgcgga tgtcgcaggg gcggagaggg cgctgaaagt cctgctggaa
    20161 ggtatccacg tccccgtctg cctccacgtc tgcggggacc tgtcatccgt catcgacagg
    20221 ctgctcgcat ttcctgtcga cgtgctcgac atcgagtgcg caaagacccc gcaaaacctc
    20281 gaactcgttt cggaacggga cctcagggaa aagaggatcg ccgtgggatg cgtggactcg
    20341 ggcacccccc gcgtcgagga cgaggacgag attgcgcgga gggtccggga tgccgtcgac
    20401 cgtcttggtg caggacgtct cctcgtcgac cctgactgcg gcctccggat gctcccgttc
    20461 gattccgcga ccggcaagct ctcccgcatg gtttccgctg tcaggaaagt gagggaagaa
    20521 ctggcagggt aatcctgtcg tatccgccta gacgacgcgc gaggtcgtgg agagctcgat
    20581 ccccttctcc gtgatgttga agggaatgat acgcttggga acctgggcgt tgcggacctt
    20641 gtggactgcc agctgccgct cgatctcggt catgatgatg atctccttga gctcgatgac
    20701 gacgtcggcc atccgcatga tcctgatctc ctcaacagtg gtgtggagat cgctgtaaag
    20761 gatgaaaaga gcatttgcct tccgttctgc aatatccttc ttgaccgagg agaggagcga
    20821 gattgcggca tcgatcccgt tcctcgtgat gattgtcgag agggagtcga gaaccaccct
    20881 gtctcccttc atcaggggaa gaagggcctc gggggggctg tgacgtgcat ccgtcatgcc
    20941 cggttccacc tcgctgtcga tcatcaggta ggtaccggtc atgccgtccg cactccagaa
    21001 ctggcgggca agcaggtcga tcccggtgag gggggaaccc tggaccacga tggtgctccc
    21061 tgccggaaaa cccccctcca tcgcgagatc cagccctgaa ataccagtcg atcgcctgtt
    21121 ctctctggcc aagagaatta tccccgctga taaatatttc tgtcccctgt cttatactct
    21181 ttcacgaaaa ctctcaccgt taccggaaat actgttcccg gagtgtgcgc ctgaggagct
    21241 tccatccgtg gacacggggc agtgacgcga cgcggatgat ctttcttggg accttgtacc
    21301 cggccagccg ttcacggcag aaaccgagga tctcctcgtc agccggctcg catcccctgc
    21361 ggacgactat tgccgctgca gggatctcgc cgcgcctctc gtccggaacc ccgaatatgg
    21421 cggcatcctc gacggccggg tgctggagga tgacgttttc aacctccgtc gggtagatct
    21481 tccaccccga catgttgatc atgtcttttt tccggtcggt gatgtagagc accccttccc
    21541 cgtccatgta cccgatgtcc ccggtgagga accatccgcc gggaaggaac gtctccctgc
    21601 tctcctcttc ccggttccag tacccctgtg ccacggcagg ccctctcact gctatctctc
    21661 cctgctcgcc tgccgggagg atcgattccg ggttttcggt atcgaccact ctcacctcgg
    21721 tatacccgac ggggatgccg acactccggt acccccgggt cagcccgggc cttccgggga
    21781 gcgttgcagt gcctgatccc acgactatcg tctccgagag gccgtaggaa ttggcaaccg
    21841 ggatccggta tctcctgtcg aatgcttccc agacggcagg caggagctgg cctcccccgc
    21901 tgatcatgac cctcacggtg gagaatgcct cctcggtgcc cggcggggcg tgcagcagac
    21961 cgtggatgac ggggggcatc gaggcgagca cggtgatccg gtactccttc acgagccgga
    22021 tgtactcggg ctccgagaac ctctccatga tgacccacgt gcccccagcc cggaggacag
    22081 cgattcccca cgacaccccg atgtgtccca tgggatagat tcccaggtac atgtcccccg
    22141 ggacgaggga gagaacctcg cgttccgcct cgagggcgga aagccagttt ccgtgcgaaa
    22201 gaatggcccc ttttggtttt cccgtggtcc cggacgtgta ctggagctgg cacatgtcgt
    22261 caaaactgca gggggctgcc ccgcccggca cagggtcccc tcctgccaga gtgtcaaagg
    22321 agagaactcc gtctcctgca cgcccggtgc agatgacgag ggacggaaag gcagggttgt
    22381 cccggatacg ctctgcaacc tccatctcgc ccccgccgca gatgagggcc cgggcccctg
    22441 aatcggcaag gaggtaggca agttcccctt cgcggagggc ggaattcgca gggaccgcga
    22501 ctgctcccgc ccgccatact gcaaagtagc tgatgagaaa cgccgggcag gagtccatgt
    22561 agatgcagac cctgtctccc ctctctatcc ccatttcccg gagggcagcg gagagggcag
    22621 agaccttccg gaaaagttcc ctgtatgtgt atttttcccc tttagacggc cagatcacgg
    22681 cgcaccggtc aggttcccgt gcacgggcct caaggaaggt cgagatgttg aaccggggga
    22741 ggggtcccgt tctcatggcc ctgcaccctg gagcgtgacc ggtcgcacca tacccttcac
    22801 ctgtactcta ctggtattcg gggagctgta cctcgcgggg caggcctccc ttgaatgtct
    22861 ggcgaatcct ttcgtagtat tccctgaggt gagggttcat ggtggggtgg accttcgaga
    22921 ggctcgcctc gaagtggcgc tttgccacgg ccggtacccc ttcccgcatg gcaaacacgc
    22981 ctgcctcgcg gcagagtgcc tcgaggtcgg agcccacgta accctcggtg cggctggcga
    23041 tctccgtgac gagtgcctcg acaaccgggt ccgccaggcg gaggtgccgg gcagccatct
    23101 gttcaacgag gtaccgccgg cacccgggac gggagagcgg gggtttttcg gatgccttca
    23161 cgtttgcggc ggcagacagg atatcttccg gcgtcacgtc cctgtccttc ccgagcgcgt
    23221 cgcagacggc atcaatcccc tcttcgccca gaggctggag gtgcccgatc acgtccagga
    23281 gtgcagagcc ctccacgggc attccccgga ggtgtatggc aaggatcttt ttccggtcgg
    23341 cgagtcccgg ttccccgatg aacaccagcc ggtcgaaccg gccgggccgc aggagcgcgg
    23401 gatcgacgag gaggggctgg ttcgttgcgc cgaggacgac cacgtccttc aattcctcga
    23461 ggccgtctat ctctgtcagg atctggttga ggacgctctc catgacgtgc gtcccgacgt
    23521 cgctcccccg tgtcggggcg agcgcatcga gctcgtcgaa gaagatgatg gccggcgcaa
    23581 cctgccgggc cttcttgaat atctcccgca cggcccgttc gctctccccc acccacttgg
    23641 agaggagctg gggacccctt atcgcgatga agttcgcacc actctcgttc gcgaccgcct
    23701 tggcaatcag tgtctttccg gtacccggcg gaccatagag gaggaccccc cgcggcggac
    23761 ggatgccaag ctcgtcgtag cgttccctct gggtgagcgg gaactcgact gcctccctga
    23821 tctcctgctt ggcctcctcg aggccgccga catcatccca cgtcacgtgc gagacctcga
    23881 gcatcacttc ccgcatcgcg ctcgggctca cgtcccgcag ggcatcacgg aaatcggacc
    23941 ctgtcaccac catcgtttcg aggacctcgg atggtatctc ctcctcctcg aggtcgatct
    24001 ccggcaggta gcgccgcagg gcacgaatcc ctgcttccct ggcaagggcc gcgagatccg
    24061 cccccacgaa gccgtgggtc tgctgggcga gtgtatcgag gttcacgtcg ggcgcaagcg
    24121 gcatcccccg cgtatgtatc ttgaggatct cgacccggtc cggctcggtc gggacgccga
    24181 tctcgatctc cctgtcgaac cgcccgggtc gcctgagggc aggatcgatc gcatccaccc
    24241 ggttggtcgc accgatcacg acgacctgcc ccctctcctc gaggccgtcc atcatggtca
    24301 ggagctgggc aacgaccctc ctctccacct caccggtcac ctcctcgcgt cgcggcgtga
    24361 tcgagtcgag ttcgtcgatg aagatgatcg acggggcgtt ctgctcggcc tcgtcgaata
    24421 tctcgcggag tttctgctcg ctctccccgt agtatttcga gatgacctcg ggccctgcga
    24481 tcgagatgaa gtgggcaccg ctctcgctcg cgaccgcctt ggcaatcagg gtctttcctg
    24541 tccccggcgg cccgaagagg aggacaccct ttggcggctc gatgccgagt ctctggaaga
    24601 gttccgggtg cctcatcggg agctcgatca tctccctcac gcgctggagc tcgtccttca
    24661 agccaccgat gtcctcgtac gatatcctct ttgccccttc cacccccggg gcaggttttt
    24721 cggagaactc gacgtgggtg ttcttcgtga tgatgactgc ttcctcgggt tcgatctcca
    24781 caaccttgaa cgggatgaac tgcgtctgga gaaagggcag tccgctcgag agcgggacga
    24841 tatcgttttt tacgacgggg aagtcgatga gcgaattgag aacgtggggc gtgatattga
    24901 tcgagacgtt ccgggggaga tcctcgggag gtgcaagcac gacccgtttt gcctccactt
    24961 cgtcctgtat ccgggatatc ttgaccgtgt caccgatgct cacgccggca ttcatccggg
    25021 tgaaattgtc gatccgcacc ttgttctggt tccagtcctc gacaagggat ctccatacct
    25081 tggcgacagt cctccttttg ccttccactg cgacgatatc cccgggtgat atcttcaaaa
    25141 agagcatggt ctcgggatcg agccgtgctt ttccgccacc ctgatctccg ggatacgcgc
    25201 tgtcaacctt cagatggagc tcatgcatta atttaaaggt gcaatacgct gggatttata
    25261 ggtacgtatg cgagtcctgt tcttcgatcc tgtccacggt gctgccggcg acatggtgtg
    25321 cggggcactc cttgacctcg gtgccgatgc cggactggtg acggcggcca tgaggtctgt
    25381 cgtcggggaa ccgtcggttt ctgttgtcac cagggcggga atcagggctg tctcggtcga
    25441 tacgcgggca actccggctg cccgcacgct cgacgaggtg atatcacggg tccgggaagc
    25501 agatgccccg gaaagtgcca tcgggatggc gtgccgcgtg ttttcgcgca ttgctgctgc
    25561 cgaggaggag gtccatggca ggtcagccca cttccacgag gtcggtgccg atgatgccat
    25621 tgccgaggtc atcggtgcat gcacggcact ctgttccctc ggtgtcgatg ccgttgcaac
    25681 ggcgcccgtc ccggtcgggg gtggtacggt ggaaacacac cacggaacgt accctgtccc
    25741 cgcgccggcg acgcttgcta tcctgaaaag atcgggcatt cctgtcatat acggcccgcc
    25801 gggagaaggc gagttatgca ccccgacggg tgccgccctc ctcgccgaga tggtcaccct
    25861 cccggaaaag gcccgtctct gcggtcgcgt ggttgctgca gggtacggcg caggggacag
    25921 ggattttccg tcggtgccca acgtcttccg ggctgttctc ctcgaggacc ttcccggggc
    25981 ccgcgatgat tctgtcgatg tactggagac gaacgtggac gatgcgaccg ccgaggtcat
    26041 tgcggcctgc tcggagaccc tgatggctgc gggtgcacgg gacgtctgca tcatcccctg
    26101 caccatgaaa aagggcaggc ccggctggct ggtacgcgtg gtctgcctgc cgggggacgg
    26161 ggagcggctc tctgccatcc tcgcccggga gacgggcacc ctcggcatcc ggtgcatcgg
    26221 gagcgtccac cgtttcgtcg ccgggagaga ggtaacagag gtatccatta ccctcaacgg
    26281 agagacctac caggtacccg tcaagtgtgc cgtattcgac ggctccgtct actcgtgcaa
    26341 ggccgagttc tcccgtgtcc gggaagtggc gcagcgtgcg tcggttcccg cccgcgaggt
    26401 cgcccggatg gcggaggaag ttgcctggaa aagggtccgc cgaaaatctc catgagcgaa
    26461 aaattccaga aaaccggctc ggacgcgctc gacgacctca tagggggggg tctctgcccg
    26521 gggattctga cgcaggtcta cggggagccc tcctccggga agagcacgat atgcgtgatg
    26581 gcttctgttg cgtgcctccg gtcgggaaaa cgtgtcctct tcctcgacag cgaggggttc
    26641 tccgccgaac ggttccggca ggtcgcgggc accgatgctc tggaactggc gcaaaatctc
    26701 ttcctgtttg agccagagga cttctcccag cagactgcga tgctccggaa cctcgattcc
    26761 ctcctgcagg agggagcggg acttctcgtt gtcgactccc tgaccgggct gtaccggagc
    26821 cagctcgaga ggggcaggga cgccatgcag aggctgacgg gacaggttct cctgctgctc
    26881 gggtacgccc gacggtacgg gatcccggtc ctggtctcga accaggtcta catggacccc
    26941 gaaaagaaca cgttcgtggg cctcggcggg acggcactcg aacacctctc gaaggtaatc
    27001 gtccgcctgg agaggaagaa ccacgtgcgc cgtgcaaccc tcgtcaagca ccggtcaaag
    27061 cctcccggta gttactttga cttcgagatc acgaacgagg gtatacgggt ttgtaccgga
    27121 gaggtcgcgg gaaaggacta gacaaaaaga tcttttccaa tacagggggt aatacgagac
    27181 gggcggagga ttgccagttt tcctggcacc cggaggagga tgccccgctg cctccggaag
    27241 gtatgccggg aaacggatca gaaggtgatc gtccccgaga agacggttgt tgccggtcct
    27301 tccatccacg tcccgtccga aaggatgatg gaaagcggcc cacccggtgt ctcgacctcc
    27361 acgggtgaat caacgtaccc caggtgatgg gcaacagccg ccgcagcggt cgctcccgtc
    27421 ccgcacgaga gggtctctcc ctcgataccc cgctcgaaag tccggattcg taacgcattt
    27481 ttcccggatc gcccaacgaa gttgacgttg gcaccctttg ggaacgtggg atggtgccgg
    27541 atgggagggg caagggcgtt gacatcgacc gagtccgggt ccccgacgaa aacgaccgcg
    27601 tgcgggacac cggtattgac agcgtacacg tcgactcctc cgatctgctc cctgtactca
    27661 ccctctccgg tcgcgggaat atcggcacgc ccgaacttcg ggtccggcat cctgatgcgg
    27721 gcaaagaatg tatcgtccct gtacccgcat tcgacaggga tgattcctgc cagcgtctcg
    27781 acggtgcatg acttgcggat attgccctgg tcgtaggcat acttggcaag gcagcggatc
    27841 ccgtttccac acatctcggc ctcgctcccg tccggctgga acaggcgcat tttcaggtcg
    27901 gctttgtccg accgggacag gaagaggacg ccgtctcccc cgatgccaaa tctccggtcg
    27961 caaaagagca tggcaaactc tgccttcatc tcgtcgggaa tcacggtcct ctcgtactca
    28021 tcgatgagga tgaaatcgtt cccgttcccg tgcagtttcg taaagtggat ctccattcct
    28081 tctcctcttt ccctgttttc ccttcacata tccctctttt ccctgccgga gtgctccttt
    28141 ctcccgcggg ctattccttc tcctcccctc cgtttacggg gaccccctgc atgaagtccc
    28201 cgatgtccca gccaaggata tccctgatga tgatgtaggc catctgcggc gggatcgccc
    28261 ctgcctcggt cacgatcagg tccacgtact ccgcgggcgt cacgtcgaat gcggggttcc
    28321 ggacacggac atgcctgaac tgtcctgcga tgtccggagg gaggacctcc gacgggtccc
    28381 tctcctcgat ccggatgaat tccccgagga tcgtccgtgg cgcgaacttg taggtctctg
    28441 ctgcgaccat cacccgtgtc cgggcctcgt gggccgcaag ggcgatctgg gcagtcccga
    28501 tcttgttgac caccgctccg ttgacggaga tggcatccgc accgacgatg acgaggtcga
    28561 cctcgttcat gaagtagcgg gcagcggagt caacgatgaa gttcgtcggg atccctgctt
    28621 cctcgagggt ccggatcgtc aggagaccct ggttccgtgg ccgcacctcg gttgcgaaca
    28681 cggaaaagtc acggcctatt ctccatgcct cgagcatgca cgcgagcgcc gcttccgagt
    28741 tgcaatgggt catgatgacg tccccgtcac ggatgtggcg ggcgccgatc tcccctatct
    28801 tttttacggc gaggagagag ccggtgatga acgtatcgca tgcccgctgg aactccccgc
    28861 gggcactccc gacggacggg taatcgcgac ggagggttgc catgacggaa tggaccgcgt
    28921 tggggagtga gacggcggtg ggccgggtgg agatgaggag tgatgccgcc tcttccattc
    28981 tctcccggaa ttccgcaact gtttccgcct gcacggagat ggcgtggtca tggagggctt
    29041 tcaccgcttc ccgggcgatg cgtccggcac ccctgacctc catgctcttt atcttctcag
    29101 cggtatcagc tagcatgaaa ggcactcgtg tacaagagtg ccccatgccc atagataaat
    29161 atagagcagg ggcgcttcca atccatgtcc gttgccgtgg ttttcgacag tgcaggcacc
    29221 ctcctgcaca catacagggt ggcaaagaat gtcctgaccg gggaactttt ccccggtatc
    29281 gagacggtca gcctcacgtt cgcctccccg gaccgtgtgc tcgtcgtcgt gcatgtccat
    29341 tcccgcgagg tgattgcggc tcccgacaac cttcccttct cgacgtacct gcgcaacaat
    29401 aacgtcggat tcgggatcag ctgcacccgg aaggtgattg ctgccgacga ggtggccgag
    29461 gcgctctaca attcccccca cggcacggtc gccgacctca aggactgcat caggaacgtg
    29521 tggcaggtct gcaggaagga gtccgtggtc acgatgaaca gcggggtgat cgtgaacatg
    29581 tccctgtccg gcatcgagtt catggtcacg acgggggggc gtcccttcga tggtgcacgg
    29641 gatgccatca gtgaactcca ccggatgggt gtcccgacct tcatcgcgtc gggtgaccgg
    29701 gtcgccaagc tcgagaagat ggccgactac ctcggtgtcc cccgggaccg cgtcttcggg
    29761 gtcgcgaccc cgacggtgaa ggcccgcatc gtcgaggatc tcaaggctga ctatgactgc
    29821 gtcgtgatgg tcggtgacgg gatcaacgat ctctgtgcca tgaagacggc ggacgttgca
    29881 atcctttccg aggaacaatc aggcgaaaag caccccgagc tttacgaagc cgccgatcac
    29941 gttgttacga gtgtgcggga agtggttggc attgtgaggg ggctggtcga ttcaggcggg
    30001 acccgcaggg ttgactgtgt tagatgaaaa gtaatatgca ccccgcacca cattctctag
    30061 taagaggact gtcaatgaac cccctgatca ccgtgaaaaa tctctgcatg gactttgatg
    30121 ggaaaaaagt cctgaagaat atctcttttg agatcggtga gggagaagtt ctgggtatca
    30181 tcgggcgcag cggggcagga aaaacggtgc tgatgcacct gctcaggggt gtggaacagc
    30241 accccacctc cgggcagatc atctaccacg tcgccgtctg tgattcctgc ccctatatcg
    30301 gggtcgggag catggcagga aaaccctgcc cctcgtgcgg cagtgttctc cgggcacagg
    30361 acatcgatct ctggaacgag aaggacgagg atctccgccg ccggctgatg cgccggaccg
    30421 ccatcatgtt ccagaggact tttgcgctct acggcaacga cagggtgata gagaacgttc
    30481 tccatgccct cgacgacatc gattacccgc aggacaaggc catcaaccgt gctgccgatt
    30541 tgctcgacca ggtccgcctc tcccaccgga tgatgcacat cgcgcgggac ctctcgggag
    30601 gggagaagca gcgcgttgtc cttgcccgcc agcttgccaa ggatccgttt ctcctctttg
    30661 ccgacgaacc gaccgggact ctcgatcccg agaccgccga cctcgtccac cggatgctga
    30721 cagaggcatg ccggcgcaac cacatgggca tggtggtgac gtcccacttt tcccaggtga
    30781 taaagtcggt tgcagaccgg gcgatgcttc tcgttgacgg aaatatcgcg atgctcggtt
    30841 ccccggacga agtcatcacg aagttcatgg cggatctctc tgacacggag acgttcgagg
    30901 tcccggagtt cggaagagag atcctgattg cccgggacgt tttcaagcgc tacatatctg
    30961 ttgacagggg ggtcgtccgg gctgtcaatg gtgtcacgtt cgaggtttac gagagggaga
    31021 tattcgggat catcggcaag agcggggcgg ggaagaccac gctctcgcgt atcatggcag
    31081 ggataatcga gcccacggca ggggagatga tcatccgcat cggggaagac gccgtggata
    31141 tgacaaaacc gggtatcgag aacaggggac gggcaaaggg gtatatcggg ctgctccacc
    31201 aggaatacga tttgtacccg cacaggacgg tgctcgacaa cctcaccgat gctataggcc
    31261 tcgagtttcc caaggaactc gcgatgagga aggctgtcat caccctcaag atggcagggt
    31321 tctcggagga gaagagcagg gagatcctcg accgcctccc gggacagctc tcggaaggag
    31381 aacggcaccg cgtggcactt gcccaggtcc tgatccggga gccgagaatg gtcatcctcg
    31441 acgagccgac agggaccatg gatcccctga ccaaggtcga tgtcaagcac tccatcatgc
    31501 atgcgaggga cgagatggac gagacgttca tcgtggtctc ccacgatatc gatttcgtcc
    31561 gggacatctg cgacaggctc gctctcatga ggggaggaaa gatcgtggcg atcggcagaa
    31621 ccgcggacgt ccttgcaacc ctcacggcag aagagaggga ggtcatggga acggcgacct
    31681 cttcttccaa ctgaaattac catgatttcc ctcctcgtcg atggagaaaa gcgcctcgcc
    31741 cgggaaggcg aaacccttgg ggacatcctg cccgggtggg accggtcctc ttacgtcgcg
    31801 gtgatccgcc ccggagcacg ggagtcatcc gtgacgggca gcatgaggct gatctcctct
    31861 gcaggggaag tggtcgtcga cctcctcccc gcaggccggg aactcttcca gtcacccgac
    31921 ctccggttgc ctctccctgt ccactggcac gacaggtatg ccgctgcctt cggaccattt
    31981 ccttcggggt tcgtcccggc ccggaaaccc cacctgtacg agcggggcga cctcatcctc
    32041 gggtgcggag ggtacgaccc gaaccgttcc tacctgatct tttcccgcat ccgccatacc
    32101 gcagaccatg gagctgcttt agaggggggt gtcatcggca gggtcgtttc cggccggggg
    32161 ctcatcgacc ggtggacgtc aggggaccgg ctgatggagg cgtttcccgt ggtcaactgg
    32221 gcagacacga gcaggtcttt tacaacgaac gacgcgtctc ttcccctcga ggacggcatg
    32281 gagatcgtga cccacgtgcg catcacggcc cacggatata ccaatggcac agtgcagtcg
    32341 acggaggccg cagataccgt ggaacacatg ctccttgccc tcgccaatga ccgtttcgtc
    32401 gtgggcaggg cctcgagcac ctacatccag gacgggagga tggccgggac ggaagtgccc
    32461 ttcgaggtaa aatccccgcg gcgcgagggg ttcgtgacgg taaggacacg gggaaaatcg
    32521 acaggctccc tttacattta cacgcgggac atcccttcgt cctcctcgca caccctcgtg
    32581 ggtcaggtca cccacggaat cgaactcgcc cggctcgccc gtgagaatga gtcattccgc
    32641 gtcagcgtcg aacccccccg ctttgacctg atagggctgt tcctgcagga agccgaggag
    32701 atcgcgtcca atcggggaat ttctgtctct gcaaaaggca agggcaatga gctggtcgtg
    32761 gtggaccagg atcccgggac aactctggag agcctcgatg cgggctccgt cgtcctcgaa
    32821 accgttcccc tcgaaaagat catcgatatc accctcgacg atgcgcacgc gccggactcg
    32881 tgcgagatct tccggaagct gacgggcctg caccggcacc gcgtgggcag gataccgttc
    32941 ttctttcact tcgaggatgt cttcctgttc aagccggcca tccctcccgg catcaacatc
    33001 aacccggaaa acctccctgc cgatgtcgtc ctgccgggga cacttgccat gacgaacgac
    33061 tcgcggaagg gttccggcct cgtcggcgtc aggataaccg agaacagcga gttcggcccc
    33121 acatccgaac cgttcgaggg cacaaacatc atcggacggg tcatcgacct tgaaaaactc
    33181 cacaaactga aggaaaacga gattgcattc ataagggaag tgagtccatg aaagcgtata
    33241 cccccctcct gaccggcacg gtcacgaagt atgtctttgt cgaatccccg gagatgaccc
    33301 cttccgatct ggccatccgg gcctacgaga tatcccaggg ggttatgatc aaggagacgt
    33361 gttttggcct ccaggtgacc ggaagggagg aggatgtaaa ccgcatcatc gattccctcc
    33421 gggcgctcga cccgacccac atctttgtca aggacagggg ttttccaccg ggcgacccgc
    33481 gacggtgcag ggcaaacctc ggcggtgcgc gtcccgggta tttcgggcac gagttcgaga
    33541 tgggtcttgt ccggttcatc tcccgcgggc tttctgcact tccctcccgc aggccggatg
    33601 atatcccccg ccccccggta ccggagaaga aagagaggct ggacgctgcc cgcctcaaag
    33661 aaatcatcgg gtcgcaggag tcctgacaat ggcaaacgtg ttcatctttc ccaccacaag
    33721 tctcatcctc tcggacctcg tggcacggtt cggccacacc ccgctctctg ccgccatgca
    33781 gatccgcgag atcgtccaga caccgggtct cgagtctccc cccctccaga tcaccccgga
    33841 ggaccccaaa aaagggctca ggtgggctgc cgtcgaggtt ccggccgggg tcagggggag
    33901 gatgtcactc tacggaccgc tgctcgaccg cgccgaggct gccatcatcg tgaacaacgc
    33961 agacttctcg ttcggctgca tggggtgtgc ccggacaaac gagctcctca tgttcctcat
    34021 ccggaagaag ggcatccccg ttctcgatct cgaatatccc gcgaacgagg aggagggagt
    34081 ggagttcgtg gctgcaatta aacgatttct cgattcactg ccgggaggcc gggcatgaca
    34141 cgcgtcagga ttgcccagct ctcctgcggc cccgagtaca gcggtgtcca gaaggagatc
    34201 aacgatgctg cagcggcggt cgatgccgaa atcttcttcc ccgacctgaa acttgcagac
    34261 atacgccagt cgttctccga gttcgggctc gatgtcagga gccctgacct caagcttgcg
    34321 attgcccggg caaaggccct cgtcgagggg cgtgtcgagg ctgacgcggt cttcattgcg
    34381 acctgtttcc ggtgcgccga ggccgccatc gtgaggaacg agctgcgccg gttcatccac
    34441 gaaaagtcaa ggctccctgt tgtcagttac tcgtttaccg aacggaccac atcgggaacc
    34501 ctcctcacgc ggatggaggc cctcacgacg atcgcacgcc gcagggccct ccttgcgagg
    34561 gaagtccagg aaggcatcac gatgggagtc gattcagggt cgagcacgac caaggctgtg
    34621 gtgatgaagg acaacaggat catcggcacg ggatggctcc ccacgacggg tgtcatcgag
    34681 agtgcagaga acgccgtctc ggaggccctc tccgcggcag ggatatcccg cgacgagatc
    34741 caggcaatcg ggaccacagg ttacggcagg ttcctcgtcg gcgaacacct caaggccgac
    34801 ctcatccagg aggaactgac ggtgaactcg aagggcgccg tcttcctcgc agacagccag
    34861 cacggtccct cgaccgtgat cgatatcggg gggatggaca acaaggccat cagcgtccag
    34921 gacgggatac cgggtacctt cacgatgggc gggatctgcg cgggcgcgag tgggaggttc
    34981 ctcgagatga ccgcgaaacg tctcggcgtg gacatcacgg aactcgggcc cctcgccatg
    35041 aaagggctct cgcagaaagt cccgatgaac agttactgca tcgtttttgg gacgcagagc
    35101 ctcgtgaacg cgcttgctgc agggagtacc cccgaggacg tggccgccgc agcctgccac
    35161 agtgtcgccg agcaggtctt cgagcagcag ctccaggagg tggacatcaa ggaacctgtc
    35221 atcatggtcg gcgggacatc ccttatccag ggcctcgtca gggccatggg tgacctcctc
    35281 cagacaccga tcacggtccc cccgtactcg cagtatatcg gtgccgttgg ctctgccctg
    35341 ctggcatcag ggttcatccg gagagagtga atggaggctg tggagtattt cgaggtggaa
    35401 tgtcccgagg cagcgggcag ggagtattac aggaagattg ccgacgtcgt tctcctcgat
    35461 cacaatctcc tccgggtcat ccggaaactc cacatcttca tcgacccgaa ggtcccgatc
    35521 ttcgttgcca cgggggtgac gcggaaactc cccggcatcg tccgtgtccg ggactttgcc
    35581 gacgtgaacg tgaaggacac caacgtgacc atctccatcg gggacgaggc gtacctcgct
    35641 ccactcctcc gcatcctctg ggacaagttc gggaaggagc gtgttaacca gcccgaccgg
    35701 ttcaccatcg tcctttcagt cggggaaggc gagggggata tcgccgatct cccggtctat
    35761 gacccgagcg aatcgatcta caaggatctc atctacgtcc tccaggtcat ccagcccgag
    35821 ggtttcaagg tacgcaggca gtattacggc gggaacaggt tctacctggt cgcaagcgag
    35881 gataccctcc ccgatgacat cgaggatctc gtcaggcaga agttcgccct catgggggtg
    35941 gaaggatgac ccatgtcccg gtgacctaca agggagggat ttacaggcac gacgagatca
    36001 tcgacctcat cgaggacctt gggggctata tcatccagaa acacgtgatt gcccaggaga
    36061 ttgttctcca ggcactcgtt ccgcgggagg atatcgagct catccggcgg atcggaaagc
    36121 ccctcaccgg ggaagtcacg ccctctcccc tcgtcggcac ggagatcgcg gtggtcaccc
    36181 cgtcgcttga gatccaccat ctcccccatg cctcgtgcga tgttgccgag tatatccgca
    36241 ggttcggggc caagaccaac atggtcggcc ttgcacgggg gttcggcaag aggatagccc
    36301 agttaaacga cgaggagagg gacatcatca acgagcacga ccttgcggta tacctcctcg
    36361 gggatttcga gacctgcatc gagcggaagt tccctgtgct ccgcaggggg atcgatgtcc
    36421 cgatcgtcct gtgcggcggt ccctcaaccg aagcgctccg caggatcatc gacccgccgg
    36481 tcgaggggta cgtggggggt atcggccggt tcatgcacag gaccaaggaa tcagaggaga
    36541 tcgggaagct ggaggaggtc gtcggggaaa ttacccgcgt tctcgaccag cggcgggagg
    36601 atcttgcccg cgatcccctc tccatctcac cggcacggtt gatggacatc atcgcggaga
    36661 acgtggagga gatccacgag gtcctctccc cgacgcccat cactgtccag atgcagggtc
    36721 tccgggtcaa gcttccctac gatacgttcg cgccggtgat caggaagctc gtgatcgatg
    36781 aaggaaccac gatcggggac cttgcaaccg tttcaccctc gcggatgcgg gactacatcc
    36841 tgctgcggat aaaaccattc tccgagacaa acatcgtcct ctgaaggggt tcgccagaaa
    36901 aaaattcaat cccccttttt caggcgatga agatctctgc catctcgtaa tggtggtaat
    36961 ctctcggcgg gaatggctgg gtcgtgaact tccacgtctt ttgcggggcg agggagttga
    37021 cgcttgcgta cgtgttcccg atgaggttgc cgtttgcgtt gtagaggttg aactggagag
    37081 tgatgtggtt gagcgtgacc tgttcctcgt tctttacctt ccctgtgagg tacttctgcc
    37141 cggtctcgtc tgtctcctcc ttaatctcga tgatggagag acgggttccg gagacgggac
    37201 gggtgaggac gtacccgtaa ggtgttgcga cgaaatgctg gggacctccc gcatcgggtg
    37261 atgcctgcgc aacccccgga acaggttctc cccctgcccc ggagggatag gtactttcgg
    37321 tcggcactgc cgtcggcggg atctctcctc cctgcctctg ttccggcagg agaacgtccg
    37381 gtgaaaggca accggctgca aggatcatta gtcccatgat gcctgtcagg gcgaggacag
    37441 cccaggtatt cccgcgtctc attcaatcca cgtccttaca cagagactgg atgctggcca
    37501 ctgataaaag atgcgcctcc aggcgggagt gcgccggggg tgtatcggtt ttgatcgaaa
    37561 aaagaggaat tttccgggat taacggaatg ccggggggat gatgtcatcc ggtccgttcc
    37621 cggaaacaag ccgcgtcagt gtccaaatga gggggagaag ggctggtgga actgccccgt
    37681 catcggcggt gacggttttt ccctggtacg tgatcctgta cgtgaagtaa tcggcacttc
    37741 cgggaggtgc ccggtaggag ggagcaagtg tctcgaagcc caatgcagcg agatccgctt
    37801 caagggactc gaggagcgcc cgggagagag tgaaattgct cctgtactcc ttcctctcga
    37861 ggactgcagt tccatcggag aaaatggcaa gatggtcgtt catgccggca aaaccacccg
    37921 ttctccagaa ctcgacgagg ggtgcgggtt ccctggcagc ctgcctcccg aacacgagga
    37981 tctccctgcc ctgggcatcc cggatcacga gggatgtgtc cctgatctcc cacgatgccg
    38041 cctgttcgag gaggttgtag tagatcgtct cctgcctgag gaactggcgg gagacgtcag
    38101 ggcagtacat catcgtggag gttaccttcc cgattttcag ggtatgccca tccacaaaac
    38161 agggtgcaga gtagagattg cagcccgatg tcccgctcac gttgcctttt ccgtcaaaga
    38221 ccgctgttac ttccttctga cggtttgcag gtgtcaggac tccttcccgc gcgattgatt
    38281 ccagtgtcca ggcgccattc agggcgctcc gggtccatcc gcctgattgc gactgcgctc
    38341 gtatggaaag gatcgtgacg ggtattcccc acatctggat tgtcggggta tcgggagatg
    38401 tccgggctga aaacgcgatc aaaaggccat cgatccggta attttccggg agattgaggg
    38461 gcaggtaatg cgtcccgtcc gaggattcga tgccatagaa tcccccttcg aggtcaacgt
    38521 accggattgt tccctcggct gttatctctt ctcccagggg ttggattgat acgatacgga
    38581 gtggttttcc ccacatctgg atggtggaga catcctgacg gagaaaaccc ctgaaggata
    38641 cgcgggtgcc ctctgccctg caggaggacg gcagtgtatc aggcaggtac cgggaaccgt
    38701 catccgcaac gatcccgaaa aaaccaccct cgaggttgac gaagaccacc gttccctctc
    38761 ctttgatgaa ttgtcgcacc ggtgttaagt ttttcaaaac cctgtctttc acccgctggt
    38821 cgaggggggt cccgttccgg ggggaaacat ttccggccgg tgaaacaggg ccggcatgcc
    38881 ccacaggaac agggttacgg gcgcttacgt ccttttgcac gggaaggggt tccatcttct
    38941 tggggatgtc cctggaaaat gttttatccg tcttcgacag ggaatatggt gaaaatacag
    39001 tggtttttcc ctttacgcta ctctgcggtt gtgcctggac cgggcctatt gcgcaaaaaa
    39061 gaagcgcgat ggcaagcacg aggcacaggg agtgttgaaa aagactcctt tttatcatat
    39121 ctctcttcct ggccggtata tcatatccgg accgagagaa aaatgcgtca ccataatgga
    39181 aaaacctgtt gaaaactgcg aatatttttg cactcatcgc gcccttccat caccctcaaa
    39241 taggggtgca gtggatatgt atgccgacga ctatggcaac cgatgacctc gtggaattcg
    39301 aacagactct taaggagatc gtcacgcggg gaggggaaga gaccgcacgg gagtggatgg
    39361 acaacatcga ggccgagtac ggccgggccc ccctgatctt caagcggatg gctgagagac
    39421 ccgaggtgct catctcgcac ctcctgtaca agggggccgt gacgcggaca agttccctcg
    39481 atcccaagta cgtggagctc atcagcatgg ctgtgggagc tgcactccgg tgccagcact
    39541 gcacgagtta ccacatgcag gctgctgcca agaaaggtgc aacgcgggag gagatcctcg
    39601 aggtcatcct cattgcaggg cttatctcaa actcctcggt ccttgcaaat gcataccgga
    39661 tctttgacga aaagatggcc cggtgtatcc cctgcgtcaa cgaggggatc gaccagcagg
    39721 tcgagtgacc tttcccttcc ctttcctgta tccgggcgcg gacacggcgg gaacgaggca
    39781 tttcctgccg tctccgatga gatccgccct tcctgccatg aggaggcctt cccggacgag
    39841 aggctggttc cgtggttccc agtactggag gagtgcccgc tggactgcct tttccctccc
    39901 ccggggaacg tggaccggtt caagggagaa cgggtcgagt cccgtgtggt acatgcaggt
    39961 cgaggctgtc atgggagtcg gggtgaagtc ctggacctgt tccgtccgga aaccgtggtc
    40021 gcgcatgaac tccgcgaggg caaccatgtc agccaccgtg catcccgggt gtcccgacat
    40081 gaagtagggg aggatgtact gccgtttctt ctttccctcc tggatctttt caaaagcagc
    40141 cacgaacgcg gtgaagatat ctgcccgggg ttttcccatc aggtccgtga catggggcga
    40201 gacatgctcc ggggccagct tgaggtgccc ggagacgtgg tgggcacaga ggtccgggag
    40261 gagcgagtac gaatcggcaa cgaggaggtc gtgccggatc ccggatccta tgaatacctt
    40321 cctgactccc gggacctggc ggagacgggc gaggagctct ttctggcggg agtgcgagac
    40381 agagagggag ggacacgccg gagagcacct cttgtccggg caggcccctg ccgtctgcca
    40441 gcgggcacat cccatgccgt acatgtttgc cgtcggcccc ccgacatcgg tgattacccc
    40501 ggagaaccca cgcagggacg ccagacgtgt cgcttcccgg acgagcgatt cgatgctcct
    40561 gctctgaacg atccggccct ggtggtgggt gatcgcgcag aaggaacacc ccccgaagca
    40621 cccgcggtgg ctcgtcagcg agaacctgac cggttccagt gcagggacgg gctgatcata
    40681 tgccgggtgg gcttccctcg tgaaaggaag cttgtaaacc gcgtccagga ccggtgtcgg
    40741 aaggggcggt gcgggcgggt tctggacgat aatgcacttg gggtgcctct gcatgacagg
    40801 tcttcccctt agggggtcct gctcccggta atggagggca aatgcccgtg catacgcttc
    40861 cttatcctcc cttaccgcgg tataggaggg tatctcgagc agcccgggat atctttccgg
    40921 atcgagatcc gggaggggga ctttctcgac ggtcccgggg atggggggca tttctcccat
    40981 cttttccccg gcggccagcc tgcgtgcgat ttcccgcaac tgctgctcgc ccatgccaaa
    41041 gacgaggaga tgcgccgggg aatcggcgag gactgactgg cggaccctgt cggaccagta
    41101 gtcgtagtgt gcaaaccggc ggagggatgc ctctatcccg ccgagaacga tgggcacatc
    41161 cgggaagagt gcgtgcagcc tgtcggagta gacgagggcg gcccggtcag gacggcgggg
    41221 tttcccgccc ggcgagtaaa cgtcttctga ccgcctcttc cgtgcaggag tatagttatt
    41281 caccatggaa tcgcagttgc ccggtgcaac cgcgaagaag aggcgtgggg ctccgagagc
    41341 gaggaaatcg tccctgcctt tccagtcagg ctgggggatg atcccgacgg aatacccctc
    41401 ttcccagaga acacgcccga taagggctgt cgggaacgcg gggtggtcga cgtaggcatc
    41461 gccgctcacg atgatgatat cgaactggtc gatacggagc cgcgctgcct cttttctgct
    41521 caccgggagg aaacgcggct gtctcttcct catcgtttta gtccggggag acatggtcgg
    41581 ggagggagag ccccgtgagc gggtccggga acctcccggt ctctatcccc ccgacctcga
    41641 agatgactgc ttcgacaacg atgtacacgt cagccgcgtc cctcatgcac cctgtcaacg
    41701 ccctgagccc tcgtccggtt gctgtgtgga ggtggacatg gggattgccg tcgctccacg
    41761 agattgtccc gatcccgacg atttcccatc cgtcccggat gtcctcgcgg tgcgggaccg
    41821 gggggaggac cggttcctcc ggcccggtta ccagatgggc cgacctgacg gcaccgagca
    41881 cctggatgaa accgcagcgg atgttctttt ccgcaacgca cgtttcgagt gcccggatga
    41941 ggtcttcccc gtgatcgata cggaggacaa agacccggcc gggacgtcct tcaatgcact
    42001 gcatgtgaca ctctccggaa aggggtgcag ggatacatca tctccctccc acccctccgc
    42061 ctccgaaacc accgccgcct ccgaaagacc ccccgccgaa accaccgccg cttcccccgc
    42121 gggacggggg actgaaggca agtaccggga taaaggccgc gttcaggccg cttgcaagcg
    42181 ggatacctgc ttccggcagg gagacgtgca ggtccttcat cgctttctcg accttgtccc
    42241 ccacaccgag cgccgtgcca tacaccagcc attctcccca catcgagata tctgccggtg
    42301 catactgccg gatgagggca aggtccgaga ggaaacgggc gaacgcatcc cattgcagtt
    42361 tctcccggta acggtcgtcc ttccagtggc caaagagcgt ggacgggaat gcaagggcaa
    42421 ttcctgactg gacgatcatc gctccaaaga ggagaactgc aggcagaagg aacgacgata
    42481 gctgcggtgt gacaatcagg gctatgatcg agacggcaca gagcgcaacc gccacaaaga
    42541 ggagggggaa gatatggtcc ctgccatcca cgatgtagcg ggcaaccagg cggggatcgg
    42601 atttccgggt cacggatagc aggtcttttt ggtacctgag gatcatccgc tcggccgttg
    42661 tgtcactccg ggcacgtgca acggtattct ggagagcttc tgaatcaact gttccctctt
    42721 ctccgatttc ctggagaaag tcaagcaccc tctgttcgta cgggtcaggt gcagtcttct
    42781 ggttcaccgt gatcctgacc ccctttccat cgggcttttc ctggattgcg atcatctttt
    42841 tccggtggag gtcgaggagg gtcgcaaagt acccgtcctc gtcaaatgtc atggggtctc
    42901 ccttgaaaag gaggttgact gcccatggtt tcatcgtcgg atcgggggta aaactcaggt
    42961 actccgggac cgtaaattcc ctctccgtcc cgtacttcct gtacaaaaag acgaggagga
    43021 ggggagtaag gacgaccatc gcaaagccga ggccgtacag cacccgggca aaataaaggg
    43081 gaaaaatatc atagaagggg tttgcagcca gagttttcgc cctgacaccg tcgacgggca
    43141 ccgggaaccc gggcaggcta tccttgtctg ccggtgcaaa gagtgtctct atcccaagga
    43201 cctcgtctgc tgcaacgttt cctgatatac ggacccattc accttcccgg gaaacagaaa
    43261 ggccgggggg atgggggaag atctcttggg cataccgggc agggatgcgt atctccaggt
    43321 gccggtaggg tatgtggcga tcgacgaggc ggaggttgag gtgcgcgtct tttgcgtcat
    43381 attcgatggg ggggtggagg gtatacgtat acgagacagt gtatgtcccg gccgggaaat
    43441 acccgggatt gtagatgccg acctcgttcc tctcggcctt gtcctcgatg aatcttacgt
    43501 acgcagggtt gtcgtcccgg tagagtgtca ctttccccga cgattcccgg atgtacccca
    43561 ctgttcccgg cggaatttcc atgtccacga tccggatgaa aggtgactcc agcggttcca
    43621 cggagagggg atcctgccag tagcggtaga gcatcctgta cgtgccgccg ctcctgacct
    43681 cgtaggtata cacctccccg aacgtgccgt tctcctgcag ggtggccctg taatccgcga
    43741 taaaaaggtc accttcgagg aggataggca cgaaaaatgc gataacaatt gccactgccc
    43801 cgatggcaag ggctactgca acgaggacga ggagatccct tttctctccg gtcagtgcca
    43861 tggtcagaac gctattttgg gtggtgtctg gatggcctct tcgaattcaa ggtactggag
    43921 cttggaaaga ccgaggatcc tcgcgatgat atttgacgga atgacgtcgc agagggtgtt
    43981 gtattgctgg gagatgttgt tgtaggtata cctctggcgg gcaatctcgt cctcgacgcc
    44041 cctgaccgag tccatcaggg tcatcacggt gctgttggtc ttgaggtcgg ggtagttctc
    44101 tgccacggca aagagccgcc cgaggagcga acgtgactcc ctctcgatct ggttgaggtc
    44161 tcccggcccg gccgagccga cgcttgcccg catcgccgtc accttctcga atgtctcgcg
    44221 ttcgaatgcg gcatagctct tgactgcccc gaggagctgc tctatcatgt cgaggcgttt
    44281 cttcattgcg acacggatct ggccaagtgt cgcttccgat gagttcttca ggctgaagaa
    44341 ccggttatag atccccacga agtagagcac cagtcccacc gcgatgacga tgaggatacc
    44401 gatgattatc cagggtatga ggtcaccaag tgccatactc atctattatc ccggggtatc
    44461 attaaattcc ccacgaatac tatccgggat acccctctgg attgcaagag agccctttgg
    44521 caggggaaga tactggcatc tgcagccttt taccttttac cttttaccaa tcgcaggcct
    44581 gcctgccggg agatggaaaa acggatgaga gggattcacc ggggtacgat cctcccgacg
    44641 acacggagct tgcccccttc gaggtggtgg atgaggactg ttgcgcccgg gggaaacacg
    44701 agttcttttt ccgaccggaa ggtcacctcc ggtctcctcc agtccccgct gttgttcacg
    44761 taggcgaccc ttgccgggat aaactgcatc cagtgaccca aatagacgac catctgttcc
    44821 ctgagaggcc ccggccagta acggacgagt tctgcccgac cgttcaggat gccggagacg
    44881 gtgagggagg ggttgttgga gaggacaaaa ccccggtcaa ggtccccggc ctcgatcccc
    44941 ttgagggcaa ggcccactct gtccccttcg gtcgcttctg gaacgtcctc gtcatgcttc
    45001 tggatcgagc ggacgtgggc gaccctgatc gtcggaaaga cccggagctc gtcgtggacc
    45061 ctgatcgtcc cctcggccac ccccccgagt acgacagtcc cgacaccttt gacggggaag
    45121 tggtggtcaa ccgggacaga gccgtacttc agccctttcg cgccggccgg ctgctttcct
    45181 gcggcctcaa ggaacatctc ccggaggtgg ttatggtcgt cgggctcgag cgtgtagttc
    45241 tcaacgaccg tccccttcac gagcgggaga acctgctcgg gggagaggta attccggagg
    45301 acaaggaccc ctttctccac cttcgctgca tcgagcatga ggacacactc cccgaatgcc
    45361 gggtttatct cgtcaacgat caggagggcc atatcagcca tggacacggc gaaaaagagg
    45421 gaggatatct tctcggggta tcggcccggc tcgacgtagg tgacagttgt ctggtccctc
    45481 ttctggttat agaaggtgat gtccgagact gtccccttct ttccgaggtg accggcatac
    45541 cctccggggc cgatgaccgc gacggtgagg ttgggcatgt gtggtagtgt a
//
LOCUS       DAOOJU010000014        39196 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1133_length_39196_cov_15.022151, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000014 DAOOJU010000000
VERSION     DAOOJU010000014.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 39196)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 39196)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39196
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1133_length_39196_cov_15.022151"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1579)
                     /locus_tag="PK679_05060"
     CDS             complement(<1..1579)
                     /locus_tag="PK679_05060"
                     /inference="COORDINATES: protein motif:HMM:NF014565.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004576 - oligosaccharyl transferase
                     activity [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STT3 domain-containing protein"
                     /protein_id="HPC55362.1"
                     /translation="MDSPDFMRYRKYLIVILLAAMALFMIWIRMLPSAAAGTTDILNL
                     VGSDDPMYNLRQVEQTIQNFPAYSWFEAMTLYPYGQVIHWGPLFIWIISALCLALGAT
                     TRPEIISVALVVPPVMAGLMVPVMFLLGKKVSGTMAGLFSALVIAVVSGQFFFRSLYG
                     YLDHHIAEVLFSTIFILCYTWTLSYVREHPVDFSRRETLRIPLVLSVSCGVAYVLGLL
                     VMPTMVLFAFIVAITTFLLFVWGFFRGVRGDSLLLLNSVTFGIAAASFLIFGVHKEGF
                     QFDYYTLGHPLAYLLIILGTAVLYVLGRFFRERGQVQYLAGLAGLFVVVFGFFAVAIP
                     GLFSTFVASIIQFFGQNQLYLTIQEARSWTIADAWDNFGLGLILLAAGLVLLCILLWK
                     EKRDEHLVVLVWSLVIIIATWQHIRYEYYFAAPLALLSGLFVGWIVGWGWKDISLLLT
                     AEKGENREGPVTDRPDAKQKGKKKAKQERAASRRDPLKIGAVAVVLLILCVFAYFQVS
                     YELRVAGSGALRMNPDWR"
     gene            complement(1875..2945)
                     /locus_tag="PK679_05065"
     CDS             complement(1875..2945)
                     /locus_tag="PK679_05065"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HPC55363.1"
                     /translation="MKAGILSGSDFSVTGGAERLIVDLARALGAEVVVPSFSEDIVSR
                     YDPGRTVPFRSLDCTLPAEPLRQVIGMRLFRKISLDYDFVICIDDMAVRYLARHVPHL
                     YYMLTPRRALYDMYYYFLAERSLPEKAVYVPGLALARYMDRRFVRKHVRNIACISHTV
                     RNRIQKVYQRDARVLYPPVHADRFSWEPPEGYWLSLGRVDKWKRVELQVEAFRMMPEK
                     RLVVVGRVYPGYEQLVRNAPENVEFKHVQGEEEMRTLYSRCEGFITTAIDEDFGITPV
                     EAMASGKPVVAVREGGYQETVLDGPCGRLVAPVPREICTAVREVGERSCDFRDACQRR
                     AALFDYPVFAARARELIRECIE"
     gene            complement(2942..4093)
                     /locus_tag="PK679_05070"
     CDS             complement(2942..4093)
                     /locus_tag="PK679_05070"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HPC55364.1"
                     /translation="MKRPLRIVLIGPSFRFLSGISYYTVRLANALSREASVRAVLFRH
                     MLPRKLFPGWKRVGQNLTAVKFAEGVDAGELLDWYNPFTWLKAARISRCADIVVLEWW
                     TSSVAHMYLAIQILLSRKTPVIIEYHEVVDSLEQSILPVRVYSRVIGRIIRRLATRFV
                     VHSGADRDLVMGTYHIPQEKITVIPHPLYDQYPALGKKQARKELGITEENVILFFGLL
                     RPYKGVKYLIRAFESLPPAVVQSTRLLIVGEAWEDRESLSLAEESPLRDKITLVNRYV
                     PDSEVPVFFSAADILVLPYTRASQSGVAHIAMAYGLPIIATRVGGLVEGMSSYAGAFF
                     INPGSVEELKSEILLRMEGKATYPIPGNLTWESIGEEWMALCSSLGGKE"
     gene            complement(4165..5904)
                     /gene="glmS"
                     /locus_tag="PK679_05075"
     CDS             complement(4165..5904)
                     /gene="glmS"
                     /locus_tag="PK679_05075"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HPC55365.1"
                     /translation="MCGIFGYTGEKRAAPLVIEGLKRLEYRGYDSFGLAVLDSDLWVW
                     KKKGKISREKPPVSRRKGRTAIGHTRWATHGEPSDTNAHPHTDCRGSVAIVHNGIIEN
                     YASLRQELLGRGHTFRSETDTEVIAHLIEEHSGGDLLSAVRAILPRLEGSYAILAVAE
                     GYEGIVAARQGSPLVLGIADRACVAASDVTALLDHTDRVIYLEDGDVALLLPPGPTIW
                     HGGKRADRPVRKVDWEVEEVRLGGFAHYMLKEIYEQQSVFSTTVRALYAEPVPDVLKD
                     ISGITLVACGTSYNASLLCQYLVEEYCGIPVRAEIASEFRYRTPPGDDLVVGVTQSGE
                     TADTLSALKKARMHNHATLVITNVLGSTATRVADHTLYMRAGPEISVAATKSFVAELA
                     VFFYIADVTSGGRLRQSILSGHEAIGEALLEDLSPAVDICKEAGSIFFVGRGPFFPLA
                     LEGALKMKEITYIHAEGYAAGEIKHGPFALLSPMTPVVALCPQAESFPAMVSNIREMK
                     ARGVPLIVIGDGKSQELRDIADVLVPLPGEDIVSEVLGSTVLLQLLAYRTAEALGREI
                     DQPRNLAKSVTVE"
     gene            complement(5907..7064)
                     /locus_tag="PK679_05080"
     CDS             complement(5907..7064)
                     /locus_tag="PK679_05080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HPC55366.1"
                     /translation="MQAVILAGGEGKRLRPLTRSRPKALIPVGNVPIIDYVIESLLAC
                     GIRDIIVVVGYRREQVISHLNDRGHPVRVVVQDKPLGTAHALVQAKEHISGRFLVLPG
                     DNYIDSASIARIMDKPDAVLVKDHPYPSNFGVVEIRRGYVTRIVEKPEQAPGFTISTG
                     IFSLDLDFFDYIRQPDLTDAVGAFLESGRKIRAVRALDWQDAIYPWDLLSMNRLLIRK
                     GRAEKAGEIAAGTVLQGHVRVGEGARIHPGCTILGPAVIGPGCEIGPHACIMPHSSIG
                     SRVRVGPFCLVENSIILDDAVIGPHSLVRDAVIAEGSQLEDHVSTVTAAPLLEIGEEQ
                     VKGLFGAVVGEKVRIGPFSTLRAAIVGNGVVIRGGRDISSTVAMGDGGLVV"
     gene            complement(7072..8271)
                     /locus_tag="PK679_05085"
     CDS             complement(7072..8271)
                     /locus_tag="PK679_05085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HPC55367.1"
                     /translation="MQCVILAAGEGKRMRPLTSTRPKVMLPLGNRPMLEHLVAAARDA
                     GITDILLVVGYREEEVRRFFGDGSSFGVKIEYAVQRQQKGTADALATAEEWVRGDFIL
                     MNGDMVLSSGDIRSIVDAGPACMGVAPSDHPEDYGVVQLEGDTVSVLREKSREPAGNL
                     VNAGIYHFGEDIFPIIGEVGLSPRGERELTDALSVLIANKALRAVRVSSWLDVGFPWD
                     LLSANEKMMENITPAIAGTVEDGAVLKGAVQVGQGSVVRAGSYIEGPCIIGKDCRIGP
                     HAYIRGATTVGDGCHIGHATEVKNSIILPGTNLPHFNYLGDSVVGSGCNFGAGTKVAN
                     LRHDRAVVHVGGHPTMRKKFGAIIGDGAMFGINCSVNVGSVIGGGAAIGPHCLVEGYI
                     APGTKVR"
     gene            complement(8285..9559)
                     /locus_tag="PK679_05090"
     CDS             complement(8285..9559)
                     /locus_tag="PK679_05090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucomutase"
                     /protein_id="HPC55368.1"
                     /translation="MHFGSSGIRAVFGRDLVDCAIALGSVLGERTGKVLLGHDTRTSS
                     PVISNALAAGVLSRGADILSAGLVPTPAVARAVPEAGLGCMVTASHNPPEYNGMKVFS
                     PGGASLTRARQAEIEAGLRESGRAAGTAVVPRFGKTSETDILTPYIAGIVDRISCRRK
                     VRMILDCGGGAGSVVSPYVLKGIGVDVTAVNCSPTGHFPRPSEPSKDALPYIGGLVRQ
                     WDMDGAVIHDGDADRMMAFDSRGRFIPGDTLLVLFARFLGARKVVTTTDASMAIGEWA
                     AVTRTPVGDSYVSEALLSGGDFGGEPSGAWIFPGQSLCPDGPYAAALFCRMASEWDIA
                     AEIDALPRYTVLRESIPCPRSAEVLHALGARVPTDGIREERDGGWFLIRASGTEPRIR
                     VTAEGKTPAAAKALLDEGLDRVRKWKKQISRE"
     gene            complement(9591..10208)
                     /locus_tag="PK679_05095"
     CDS             complement(9591..10208)
                     /locus_tag="PK679_05095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55369.1"
                     /translation="MKRDRMDIVKDAVRKLEELTRGCGCEDGNIVLSVNPERTVCQFE
                     KGACMEASFGGRTAEFVTFEPTRATTRLPFLFRATLDKTVHRAAACAILNVMTGFLCI
                     SRARLSCEPECHAACRADLIEKVGERVVGGLHIPPHVPGQFPRHTDVPGGGEVVLVGG
                     EGLISPEACDLFGGERAGSVLLVGPSTAGVATLENLPHWCPYGKG"
     gene            complement(10205..10801)
                     /locus_tag="PK679_05100"
     CDS             complement(10205..10801)
                     /locus_tag="PK679_05100"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HPC55370.1"
                     /translation="MVYHDVTRPLKEGIAVYPGDIVPSFRQEDRGRYLLSDLRLSTHS
                     GTHIDAPSHYIRGAMTIDMIPIENLVGECTVVSVPGKESVIGTCDLRPGTERVLFRTW
                     YSGEDTFRDDYPGLSRQCAATLAGLGIRCVGIDSPSIEPYDGDGTVHRTLLGHGITVI
                     EFLDLSAVGPGKYWMVALPLRLEGLDGSPCRVFLGDTR"
     gene            complement(10809..11459)
                     /locus_tag="PK679_05105"
     CDS             complement(10809..11459)
                     /locus_tag="PK679_05105"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004719 - protein-L-isoaspartate
                     (D-aspartate) O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="HPC55371.1"
                     /translation="MAEDPYAGEREAMIATQIEARGISDRRVLEAMRKVPRHLFVPPG
                     YASAAYRDHPLPIGHGQTISQPYIVALMTELLAVSPGDRVLEVGAGSGYQAAILATLG
                     AVVYSIERIPEVAKSAEENLKRAGIPNVHVIVGDGTRGHPPAAPYQGIIVTAAAPAIP
                     RPLVEQLAEGGRLVAPVGSRDLQELVKLEKREGRVTKTSYGGVVFVPLVGEHGWEG"
     gene            complement(11561..12676)
                     /locus_tag="PK679_05110"
     CDS             complement(11561..12676)
                     /locus_tag="PK679_05110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HPC55372.1"
                     /translation="MPEDPVKMSELSPEDRERLTLTGLEVEMKNREGSFFQVDQEIRQ
                     WTSLNEGIEILPIHEALRKYDWLSGYSWNLVKKDKDQYTKYVADQPEPRGFVIIARKG
                     SKTIYPLQACLFLARSPVQHVHNIIIAEEGAELHIISGCASASYTKTGSHIGVSEFYV
                     GRGARITSTMIHNWGEEISVFPRSAARVEEDGVFISNYVCMQPVRKVQMAPFVDLAGR
                     NAIARFSSIVVCTQGSYMDLGSVARLAAEGSGAELVTRAITTGGTIISRGMIEGAARH
                     TKGHIECRGLILRDGVIHAIPEIKGDVVDTELSHEAAVGKIARDEIEYLMSRGLDEDV
                     ATATIIRGFLDVRIAGLPDALQAQIDAAIDSAEKSGF"
     gene            complement(12658..13392)
                     /locus_tag="PK679_05115"
     CDS             complement(12658..13392)
                     /locus_tag="PK679_05115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55373.1"
                     /translation="MLEIEDLHVKIGDREVLHDINLTIREGETHVLMGPNGSGKTTLL
                     RAIMGFSGLDVTKGTIRFKGKDITNLPIHERAKMGIGMLFQRPPTISGLKLGKLLAVT
                     SGDRTAMVSEYARFLHMDAFMDRAINLGFSGGEIKRSEVLQLMVQQPDFVMLDEPESG
                     VDLENITLIGNAIARLLEKDVHIVNRKKSGLVITHTGYILDYLDADFGHVMCDGAFRC
                     HGNPREILKVIKTSGYKECLACQKIQ"
     gene            complement(13469..14611)
                     /locus_tag="PK679_05120"
     CDS             complement(13469..14611)
                     /locus_tag="PK679_05120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55374.1"
                     /translation="MGTRTLLSVVLAIALFMTGAGCLDLLPWTHPPAIYPSIVPVQGG
                     AMPRPPVYRFPFQDYSVTIDVPVDAAVYAGARNADKGARIFDQDITEDEWRAGIYRAL
                     MEDPEQEGFFAGLLSALRSVRDTRALDSDEYAELLAVFVQSIPYETRKSSDPRFPVEV
                     YVDGAGDCDDKSLLLASLLAREGYRAALLYFGPEAHMAVGVGCSGPGYRHTGYAYIET
                     TNVTFVGVPPRELAGGVRLESFPTIIPVGSGTLNYTRCPETGALSRAMEKMGDEADSL
                     RVRIRDLEEDLLHKKSELEALRVEMEGMKRHGNVAGYNSRVARYNAGVTEYNTMRSRL
                     SDLVTRYNRLVDTYNTLSSHQFDRKGMYAGLASVGDPSDPRGSVPA"
     gene            complement(14617..15522)
                     /locus_tag="PK679_05125"
     CDS             complement(14617..15522)
                     /locus_tag="PK679_05125"
                     /inference="COORDINATES: protein motif:HMM:TIGR01458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01458 family HAD-type hydrolase"
                     /protein_id="HPC55375.1"
                     /translation="MGKQACAGTIMGAADEKCTVTGCPIKTREDWAGIGKGCGMAGIR
                     GFLIDIDGVISTGSDPVPGAAGTIAWLQEAGYSFRFISNSTRRSVQGISRRLTGMGIP
                     AGPDSILTPAVAAASLARQRGWSRAFLVTTEDVKEDFLRAGIVPCGEACDCIVVGDCG
                     KSFSYDTLNAAFRLAIAGTPVLALEKDRYFRDDDGLSLSAGPFVAALEYAAGRQAELV
                     GKPAQSYFLAALASLGLAPGEVAMIGDDAISDVQGAMDAGMAGILVRTGKYSPDALLA
                     CRRPPTAVLPSIAALREYLEGRGTG"
     gene            15598..16668
                     /locus_tag="PK679_05130"
     CDS             15598..16668
                     /locus_tag="PK679_05130"
                     /inference="COORDINATES: protein motif:HMM:NF024873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H-like domain-containing protein"
                     /protein_id="HPC55376.1"
                     /translation="MTMPLVFETASRLWRDRVTGSQEYSVIKNDRLHRAFLSRSPVPE
                     SEYRAAVSYRTALLRMFQDRTLEDVFPGRFVATPEGDTYCISRRHPLPLPPWDGDSTR
                     RALLADLSLVYGIGKHTKRYLKGRGYRTIPDLLQHRRFSAPARECLRVLEEGSPCDVL
                     SLVSRWYPPSHSRHLASARLFDLSDFLFLDIETLGIFQRPIILVGVAFVEGGRLATDQ
                     FLVRSMEEELPALLAAGEAVRKRGVLVTFNGRAFDVPYLRERCALYGGMFPAAVTHFD
                     VLHPARRLFGQKYPDCRLCTLERGLFGITRDQDVPSMMVPEFYEAYAIHDNPGPLVPI
                     VEHNCQDLVSLARLFFHLVEAA"
     gene            16665..18929
                     /locus_tag="PK679_05135"
     CDS             16665..18929
                     /locus_tag="PK679_05135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HPC55377.1"
                     /translation="MTVPGDALRSLRGDSRLADGWIHAEEIPPREPRYGTPDPPFPGQ
                     IQEFLDSRKIRLYSHQCEAAQAFREKKNVVMTTPTASGKTLAFALPVFEALLTQPGST
                     FLFLYPTKALTRDQHKTLRALEEGFCTGAVSAVYDGDTATSARARIRQEARIVLSNPY
                     ELHNILSWHHQWSQFFSGLSAVVIDEAHRYRGVFGSHVALLLRRLRRVCRFHGSHPLF
                     VLSTATLANAGQFAEKLCGVPFEQITRDGSPAGHRTIAFYNPCREWPADRSMHRDSAL
                     ILALCTQAGLQTLCFSGSRRTAELVASWAREFAAEPPRHVPAEKIASYRAGYLPEERR
                     AIEEGLKSGALRGVVSTNALELGIDVGTLDAVVLSGFPGTMMAAWQQAGRAGRGARDA
                     LAILVASPNPLDQYFMRHPSAFFGAPLEHAIIDIENPYILSGQVLCAAAELPLDCEAD
                     RDLFPPALPEIVSSLAGQHLLGRTRRGWIYAGSRRAADLVSLEGGSRETFTVMCNGHV
                     LETLDRAQAYREAHKGAILLHQGEQYRVDDLDLDARTVRVTPVTVDYYTRPQKSAAVR
                     VLEVKACRDLSGARLFFGDVEVTEQYTAYRMIERETVIGVEPLDLPPSRFATRCLWFE
                     LAPGTCDAVTRAGGDLAGGLHGMEHALIAVMPFFVLCDRWDIGGLSVPCGGESGYPAV
                     YIYDGYEGGIGLAEKGYEICEDIVATAGSLVADCPCTDGCPSCILSPKCGSDNQPLDK
                     KAARLLLSLVLTAG"
     gene            complement(18949..19746)
                     /locus_tag="PK679_05140"
     CDS             complement(18949..19746)
                     /locus_tag="PK679_05140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 encapsulin nanocompartment shell
                     protein"
                     /protein_id="HPC55378.1"
                     /translation="MSSHYLGRSDAPISAETWALLDRAMVDSAKSVLAGRRLLEIEGP
                     YGLGLKAVPLEDCRVSECLAVSQFVPVHMVSTRFSLGLRDIVSYEQNGLPFSAAPAAQ
                     AAIECARQEDALIFEGAAGIAGLTTHEATGSYALSSWNTVGKAADDIIQAMITLDEAG
                     YHGPYALALAPARYNLLFRRYLQGQSTELEHIRTIVTDGIFKAPVLKSGGVLLATGKR
                     YASIVLGQDMMVGYVGPAGDSLEFSITESLALLIREPASICVLRDRK"
     gene            complement(19756..20097)
                     /locus_tag="PK679_05145"
     CDS             complement(19756..20097)
                     /locus_tag="PK679_05145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin family protein"
                     /protein_id="HPC55379.1"
                     /translation="MKSDRKLTQAELVRAIRLMVAAEYEAVQMYIQLAESIDNELARE
                     VLIDIANEERVHAGEFLRLLQELAPDEPEFYARGAAEVEAGIAKRAKPEGAGMAEEKN
                     DNSLTIGSLKG"
     gene            complement(20311..20754)
                     /locus_tag="PK679_05150"
     CDS             complement(20311..20754)
                     /locus_tag="PK679_05150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD synthase"
                     /protein_id="HPC55380.1"
                     /translation="MRRVVATGTFDILHPGHLYYLEESRRLGDELYVIVARDRNVKHK
                     PKPVIPEGQRVKMVAALRVVDHAVLGDLHDMFRPIEEIRPDVITFGYDQHFDEEKIRG
                     ELEKRGLSPRLVRIGQYRGDPVCSSREIVRSVREREEDNPGTSRD"
     gene            complement(20751..21122)
                     /locus_tag="PK679_05155"
     CDS             complement(20751..21122)
                     /locus_tag="PK679_05155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HPC55381.1"
                     /translation="MTIRGIRRALLDLLLEIGRESHPREFAGVLREEEGIISEFSLLP
                     GTVTGGESATLFLDMMPLDTHLAGSAHSHPNGVLSPSQADLSFFPRTGRYHLIVGYPY
                     DRESWRCFYADGRPAELEVVA"
     gene            complement(21181..22593)
                     /locus_tag="PK679_05160"
     CDS             complement(21181..22593)
                     /locus_tag="PK679_05160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase-like protein"
                     /protein_id="HPC55382.1"
                     /translation="MRILLPTGRATRAVVEDAARGLDARVVVTGEIASFLTPDQLQGL
                     IMEDHYDMVIVSGMCVASFRGVEEATGVPVYLGPRHAADLPFVLSLLPEITLSRTIPA
                     DDFLVEKRRKEAESRIAAAEAASDCAFVIRGVRIGGTSRMKVLAEIMDAHRVPDIRKR
                     VEDFFARGADIVDLGFSFDATPRDVGAVFSQLEDIDGPLSVDSQDPALIEAALGRADL
                     VLSLQEDNIPIAGKAIADAGIAAVVVPGERGLSANLEAARSAGIECLLADPILPPAGS
                     GLVGALGRFSGYDTPLFFGAGNVVELLDADSIGQNALLAAMAAELGAAVIFTSEHSDK
                     TRGSVREMRRATEMMVLSRDRPYPKDLGIDLLVIKEKRRRREPPLEYSRSIRAGPAPG
                     EIQYDPRGNFRIGIEGDEIVAVIHGTAYRGTSWNSVFSAILAGGDVSLLDHAAYLGAE
                     LFKAELAIRYGRSFEQDGPF"
     gene            22636..23304
                     /locus_tag="PK679_05165"
     CDS             22636..23304
                     /locus_tag="PK679_05165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HPC55383.1"
                     /translation="MLACDLHIHTDHSRDGESSVEEVIRRAEAAGLDVIAITDHDTVS
                     GALHALSIPTRLIVIPGTEVSTRQGHLLVLGINAPVPRGLDMGESIRIAKEMGGLVIL
                     PHPFHIWRHGAGRKIDAWVRDLDAIEVFNSRYIVGSANRKAERVAGRLGKPCVGGSDA
                     HNARFVGYGRTLVESERSLPAVLDAIRAGRTLAYGRMTPLRTYTRQSLRNTWKRISHR
                     ITQR"
     gene            23268..24137
                     /locus_tag="PK679_05170"
     CDS             23268..24137
                     /locus_tag="PK679_05170"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase A"
                     /protein_id="HPC55384.1"
                     /translation="MEEDLAQDHPEVTRLAFRCGYIGDRFSGSQVQSGARTVEGEFIA
                     ACLRLSLFPDPRAGRFQAAGRTDRGVHARGQVFCISTPFPDRAINLLRYHLPADLWVT
                     GVARVAPGFHPRHGAIHRTYRYFFGERDLDVQPMDRAARAFEGTFDFSLFARPDGRDP
                     VRTVLSARVFEESGIVVFEVRAESFLWHMVRYMASALRLVGTGEADEKLVSSRLSGDP
                     RGRLSPAPPGGLVLWDVSYGFPFDPLDAGKKARTYLEREYVSSRVRACVAGHLADDAC
                     PCDSVAPPREEIP"
     gene            24134..24625
                     /locus_tag="PK679_05175"
     CDS             24134..24625
                     /locus_tag="PK679_05175"
                     /inference="COORDINATES: protein motif:HMM:NF015639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC55385.1"
                     /translation="MTAFPCSRCGKCCMSLGRHIRVIKTTSPRSFLISVGVTRETLPV
                     QLVPSLVSLYSQKEPPAWETGWCPFLRREAGGLFSCTIYPFRPRICRGFRCMTMRILD
                     RSGHEAGRVKGRSSLVSDDPRLVELWDDAVAPLAGLPQKEFVSRCREILASHGFEVDM
                     FDE"
     gene            24740..25021
                     /locus_tag="PK679_05180"
     CDS             24740..25021
                     /locus_tag="PK679_05180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5320 domain-containing protein"
                     /protein_id="HPC55386.1"
                     /translation="MPGRDGTGPLGRGPMTGWGMGRCRPSGVTPVPPQAQQQAAPAGG
                     QGTQEPTGQSPAGIAAPRGYPVVYGRGRGGIPWGCGRGFGRGRCWRFFR"
     gene            25070..25288
                     /locus_tag="PK679_05185"
     CDS             25070..25288
                     /locus_tag="PK679_05185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55387.1"
                     /translation="MADKTRMKNDMSPSPSPHHSVAGPRAKSIPLRTALRIARERQRS
                     RSSRRKIFREEPERYLDIVRLMKESGGI"
     gene            25389..25763
                     /locus_tag="PK679_05190"
     CDS             25389..25763
                     /locus_tag="PK679_05190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF134 domain-containing protein"
                     /protein_id="HPC55388.1"
                     /translation="MATDVVARGPNRRRGRPRMPRALGEPLSSRCFAPECAPDEEGLA
                     ITLLPEEVELLRLVDLGGLEQEEAAAVLGVSRRTVWRDLHTARRKVAEALTTGKCLRM
                     DRCPRVDEGKCPRKCRRGMQET"
     gene            25971..27596
                     /gene="atwA"
                     /locus_tag="PK679_05195"
     CDS             25971..27596
                     /gene="atwA"
                     /locus_tag="PK679_05195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl coenzyme M reductase system, component
                     A2"
                     /protein_id="HPC55389.1"
                     /translation="MNPPFISVRNLSMEYSGKKVLDNLSFEIYEGETMGIIGRSGAGK
                     SVLIHLLRGVEDPPTAGAIVYHVSMCPHCATVGLQSDAGKPCPRCGTTLGKADVDFWK
                     PENEALKKQIMRRTAIMFQRTFALYGDDRVIENVLRALDDVDYGEGAINRAADLLDRV
                     RLSHRMMHIARDLSGGEKQRVVLARQLARDPLLLFADEPTGTLDPQTAAIVHQMLRAA
                     SKDSGMGIVITSHFSRVIEDTAARAILLDEGRIEKIGAPGDVISHFLRDYAREEDESP
                     VTIGEDILVARDVAKRYMSADRGLIRAVNGVSFGVRRGEIFGIIGKSGAGKTTLSRII
                     AGIIEPTAGEMNFLVGDEWIDMTKPGIENRGRAKGYIGLLHQEYDLYPHRTVLDNLTD
                     AIGLEFPKELAVRKAKITLAMAGFSDKVSGDILSKYPDQLSEGERHRVALAQVLIREP
                     RMVILDEPTGTMDPLTKRDVKHSILHARQEMDQTFIVVSHDMDFVRELCDRVAWMRGG
                     KIVAIGTVPEVLRAMPPEEGGISSAGEAPGQVT"
     gene            27729..28610
                     /locus_tag="PK679_05200"
     CDS             27729..28610
                     /locus_tag="PK679_05200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HPC55390.1"
                     /translation="MTEIPREEYILKCTSACAGCGDSLSLRYVLKAAGPDTVLVVPAC
                     CTSVIQGIYPNTAFNVPVYNVAFAAAAACASGMSAALRAAGKKTNVIAYAGDGGTVDI
                     GIQALSGAFERGADFLYICYDNEAYGNTGMQRSGATPLGARTTTTPAGKMQPKKDLDA
                     IVAAHRPPYMATACPAYPKDLFQKVKKALSYRGPTFIHILSPCPPGWRFSTEKTVEMG
                     KLAVRTGMWILYEREQGKVTINGPSKAAMVKPLPVEEYIRAQGRFKGISAETVARMVD
                     DAAALARRLQKEEEGIC"
     gene            28604..29716
                     /gene="porA"
                     /locus_tag="PK679_05205"
     CDS             28604..29716
                     /gene="porA"
                     /locus_tag="PK679_05205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate ferredoxin oxidoreductase"
                     /protein_id="HPC55391.1"
                     /translation="MLTVATGNKAVAAAVKEAAPAVVAAYPITPQTEIVEQIAEYVSS
                     GELKSQYIPVESEHSAMAACIGASVTGARTFTATSSHGLHYMHEMVNWAAGARLPIVM
                     ANVNRALGPGWNIWAEHTDAFQERDSGWLQVYVGSVQEAFDAVLMAFCIAEDERVLLP
                     VMVNLDGFLLSHTMQPLEIEKAGDFIPPLHLPHAIDPQNPCGYGTLTGPDEYFRLRWD
                     IERSMRDAVDVIRGTQERFARRFGRKYGMVDEYRCDDAEVVIVAAGTLGREAEVAVDL
                     LRDEGTRAGSMRIRWFRPFPRLDLSGRDVVVIDRDYSFGFGGVLAKSIAATEGAKPFS
                     VIAGLGGQEVTYEDIAGFVRNRQPGRELWFGVNGDV"
     gene            29709..30236
                     /locus_tag="PK679_05210"
     CDS             29709..30236
                     /locus_tag="PK679_05210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HPC55392.1"
                     /translation="MFEVRIHSRGGQGGVTAARLLALAAVRDGKYATAFPFYGAERRG
                     APVVSFVRIDDAPIRVSSQIKKPDLVIVLDPSVMDVVDVLQGLKPGGRVLLNARERRD
                     MKGYPTFTVDLTGIALREKLEVAGSPILNTPVLGALAKMGIVTMESAKSAITEMFSDP
                     RNVSAAEAAYRELVA"
     gene            30233..30484
                     /locus_tag="PK679_05215"
     CDS             30233..30484
                     /locus_tag="PK679_05215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC55393.1"
                     /translation="MKQRRRLAISRPTTGACGKTGSWRVFRPRIDREKCNACGICAMY
                     CPDAAISEDLEIDYDFCKGCGICANECPKSAITMEREEK"
     gene            complement(30590..30958)
                     /locus_tag="PK679_05220"
     CDS             complement(30590..30958)
                     /locus_tag="PK679_05220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55394.1"
                     /translation="MQDRFIFTRYRTTCYHCGKEADQVIKAVPFQAQVICSNCGATRI
                     FVPRIEDVSKPGSFTRIGCYDLWTLVSDAQCRNCGVTGPHDLSIGCNHFTVRCRNCGF
                     THFYTFSLEYIAQCPIEEET"
     gene            complement(31139..32797)
                     /gene="thsA"
                     /locus_tag="PK679_05225"
     CDS             complement(31139..32797)
                     /gene="thsA"
                     /locus_tag="PK679_05225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thermosome subunit alpha"
                     /protein_id="HPC55395.1"
                     /translation="MSQQLGGQPILILKEGSSRTRGRDAQGMNITAAKAVASAVRTTL
                     GPKGMDKMLVDTIGDVVITNDGVTILKEMDIEHPAAKMMVEIAKTQDDEVGDGTTTAV
                     VIAGELLKRAEDLLEQDVHPTVIAHGYRQAAEKAQEILQNIAVTIKPKDTAMLKKIAE
                     TAMTGKGAEGSRDKICDLVVKAVTMVADEDGTVDKDYIKVEKKVGGSIDDCEIIEGVV
                     IDKERVHPGMPKKVTNAKILLLNAPVEFKKTEVDAEINITSPDQLQAFLDEEERMIKS
                     IVDKIVASGANVLFCQKGIDDIAQHYLAKAGILAIRRVKKSDMEKLVRATGGSMVSSI
                     DAIAREELGKAGLVEERKVSGEEMIFVEECKNPKAVTIMVRGGTEHVVDELERAIEDA
                     LRVVSVVYEDKKLVAGGGAPEIELSLRLREYAATVGGRAQLAIEAFANALEIIPRTLA
                     ENAGLDPIDMLVELRAAHEKGKKTYGLNVFEGKAEDMLKSGVIEPLRVKTQAIASAAE
                     AATMILRIDDVIAASKSAPPAGGPQGGPGGMGGMGGMGGDMGDF"
     gene            complement(32852..33763)
                     /locus_tag="PK679_05230"
     CDS             complement(32852..33763)
                     /locus_tag="PK679_05230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HPC55396.1"
                     /translation="MSQERLLSTVTSVLLMGGFRVSEKFSMRPRSFDMVARKKNVILV
                     IKAVTHIDSVGEDTARDLDHVARYLKGSPLIIGERARDAELERGAVYVRYGIFAISVA
                     TLYDAFVEGVPPLVYASPGGLYVNINGDVLRELREKRNLSLGDLGSMLGVSRRTISKY
                     ESGMGTTLDVAQKIEEIFDAPLVRAIDLLAYRSVFADEGEAPEESPMGFLERIGVKLH
                     AMHRAPFQALIEISDESILTGYGSSQKVVKRAALIGNISQVTGMHAMCVLTDYHKQKR
                     IGKTLVIGEQRLQTLQDGEELIELVCK"
     gene            33822..35069
                     /locus_tag="PK679_05235"
     CDS             33822..35069
                     /locus_tag="PK679_05235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Ile)(2)-agmatinylcytidine synthase"
                     /protein_id="HPC55397.1"
                     /translation="MFRIGIDDTDSPAGMCTTYLAAVLSRRLKRAGIRVFEARLVRLN
                     PNVPEKTRGNAAICLVAGGSLRVAFHLACETVGELAEMSHEGTHPGVVACERIPPPDF
                     YLRAVRGFCTLDEARALLSEWGALSRGYKSGRGLIGATAAVCSQFDDSTCELLAYRRR
                     ARFGTPRSVDRESLFAADSFTFPHTWDTVDRENDIVVCVPHTPDPVLFGIRGERPGWL
                     ALAREKVISEDPACEQIFVTNQGTDAHIVPGTIGCLEEGHSYIVGGTVLSLPRTARGG
                     HVCLTLGNGTGTLPCMAYEPTRGFRDIVRSLRPGDRVRAAGSYKRGSLNLEKIEVVSA
                     PPLRLVRPPICERCGKRMTSAGKGKGYKCRRCGGRKDAPEEVIQPRTVSPGWYEVPPS
                     ARRHLARPLCRGVREDFLRLPPP"
     gene            35137..36066
                     /locus_tag="PK679_05240"
     CDS             35137..36066
                     /locus_tag="PK679_05240"
                     /EC_number="2.5.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyhypusine synthase"
                     /protein_id="HPC55398.1"
                     /translation="MECGESVEQIVLRPKMTVGELVAAMGRAGAYNGGALARAADIYE
                     AMLRDKAVTRFVGLAGAMVPAGMGRIVSDLIDAGFVDVLVSTGANLTHDIIEALGCRH
                     YHGTASCSDVALRDAEINRIYDVFLPNESFIRFEEFMQERFGDLAPQAPLTVRKFLAE
                     VGASLPSGILASAARNGVPVFCPALADSMAGLQYWLYTQTHRPILDAFGDMQDLLSLC
                     FSAESAGALLVGGGVPKNYILQSMLMTPKGFDYAVQLTGDRPDLGGLSGATLDEARSW
                     GKITASARAVTVYGDATITLPLLVAAVRERLGV"
     gene            36063..36698
                     /gene="pyrF"
                     /locus_tag="PK679_05245"
     CDS             36063..36698
                     /gene="pyrF"
                     /locus_tag="PK679_05245"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HPC55399.1"
                     /translation="MTDLVLALDVTDPQRAVSVAAACAPHLDAIKVGYPLVLRSGLSV
                     ARDLSSLGLPLVADFKVADIPNTNRLIAEAVFSAGFEGIICHGFCGEDSVLACVETAH
                     GQGGRCFVVAEMSHPGALTFFSAGVPERIARMAVSLGADGIIAPATRPERIRALRSIV
                     RDRLIWSPGAGAQGGDPKVIAPLVDGIIVGRQVYQSADPAAEAAALGFLRR"
     gene            36809..37171
                     /gene="nrdD"
                     /locus_tag="PK679_05250"
     CDS             36809..37171
                     /gene="nrdD"
                     /locus_tag="PK679_05250"
                     /EC_number="1.1.98.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HPC55400.1"
                     /translation="MQWSEEQLILARSLRRLEDIPPAERRYKCHSCHLVVDETPCPVC
                     GDTHLEIMCPLDHCHCSHEIVSSIEYCPLCGAPVCPECGSHDVVQISRVTGYLQEVSG
                     WNAGKQQELKDRVRYTLA"
     gene            37267..>37984
                     /locus_tag="PK679_05255"
     CDS             37267..>37984
                     /locus_tag="PK679_05255"
                     /inference="COORDINATES: protein motif:HMM:NF015997.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HPC55401.1"
                     /translation="MRYYIRDNTLFLRGHFRAAGTGTPGGLRPVPTIVVHGPPAAGDE
                     ADSLRILERAVRREGLPPDFFGVFAGAHPSRLCILQYDSLMVFIAPGPGDGSGGGFSI
                     VVYSGEGLSDAALLGALVTATAARMAVLYGRDGAGRLESPQDTLVVACEGEVVHADAS
                     PSSAIGLRIGEAVRFGTRTVMERSAGSRGPEKRPSFFIYSRYQGDHWAEWVPEECPYY
                     PCHFPGQRCDFCYCPFYPCGD"
     assembly_gap    37985..38084
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <38085..38303
                     /locus_tag="PK679_05260"
     CDS             <38085..38303
                     /locus_tag="PK679_05260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HPC55402.1"
                     /translation="FPGQRCDFCYCPFYPCGDESLGQWVQSSAKNGLVWNCSTCTLLH
                     EPAIADYLLAHPEASLRELKAKKAREKK"
     gene            complement(38310..38504)
                     /locus_tag="PK679_05265"
     CDS             complement(38310..38504)
                     /locus_tag="PK679_05265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HPC55403.1"
                     /translation="MGITADSTIYDLLKTKPESAEVLFKFGMGCVGCAIARGETIREA
                     AMAHGIPLDELLSALGVEQG"
     gene            38622..>39196
                     /locus_tag="PK679_05270"
     CDS             38622..>39196
                     /locus_tag="PK679_05270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding protein"
                     /protein_id="HPC55404.1"
                     /translation="MDFSETAERISQKVMSHGHAVEKTAIETKLRRLVEEFGVPLAEA
                     ERTVTNEMAREFSISGLQAGGPGEAKTLDALVPGEWVTVECKVVALTAPPSPSISQTG
                     IAADQTAAVRFVVWSRANAPVLKEGNWYRFESAVVDQYRGSVNLKVHSGTTIREVPGG
                     GAIKPVITPIAALRPGIASVRGKVIQEWEAT"
BASE COUNT         7139 a        12529 c        11919 g         7509 t
ORIGIN      
        1 cgcgccagtc ggggttcatg cggagcgctc cggaaccggc cacccggagc tcgtaggaga
       61 cctggaaata agcaaatacg cagagaatga gaagaaccac tgcgactgct cctatcttca
      121 gggggtctct cctgcttgcc gcccgttcct gctttgcctt cttcttccct ttctgttttg
      181 catcaggtct gtccgtgacc ggcccttccc tgttctcccc cttttccgcg gtcaggagca
      241 gggagatgtc tttccagccc catccgacga tccatcccac gaaaagtcct gacaggaggg
      301 cgagaggggc tgcaaaatag tattcatacc tgatatgctg ccacgtcgcg atgatgatga
      361 caagggacca gacgagaacg acgaggtgtt catccctctt ctccttccag agaaggatac
      421 agaggaggac gaggcccgcc gccagaagga tcagaccaag tccaaagtta tcccacgcat
      481 ccgcgattgt ccatgaccgt gcctcctgga tggtgaggta aagctggttc tgtccgaaga
      541 actggataat actcgcgaca aaggtggaaa agaggccggg gatagcgact gcaaagaacc
      601 cgaacacgac cacaaacagg ccggctaatc ccgcgaggta ctgcacctgc cccctttccc
      661 ggaagaacct cccgaggaca tagaggactg ccgtcccgag gatgatgaga aggtaggcca
      721 ggggatgacc aagggtgtag taatcgaact ggaatccttc cttgtgtacc ccgaagatga
      781 ggaaactcgc agcagcgatg ccaaacgtca cggaattgag caggaggagc gaatctcccc
      841 tgaccccccg gaaaaagccc catacaaaga gaaggaacgt ggttatagcc acgataaatg
      901 caaagaggac catcgtcggc atcacgagga gtccaaggac atatgcaaca ccgcaggaaa
      961 cggacaggac aaggggtata cgcagtgttt cgcgcctgga aaagtccacg gggtgttccc
     1021 ggacgtagga cagggtccat gtataacaga ggatgaagat tgtgctgaag agtacctcgg
     1081 cgatatgatg gtcgaggtat ccgtacaggg agcggaagaa gaactggccg ctcacgacgg
     1141 cgatgacaag tgccgaaaag agacctgcca tggtccctga gaccttcttc ccgaggagga
     1201 acatgacggg gaccatgagt cctgccatga cgggtggcac gacgagggca acggatatga
     1261 tctcgggccg ggtcgttgca ccgagcgcaa ggcacagggc tgaaataatc cagatgaaaa
     1321 gcggccccca gtggatgacc tgcccgtacg ggtagagtgt catggcctcg aaccagctgt
     1381 aggcagggaa attctggatc gtctgctcga cctgccggag gttgtacatc gggtcgtcgc
     1441 ttccaacgag gttgagaatg tcggtcgtgc cagcggctgc cgaggggagc atccgtatcc
     1501 atatcatgaa gagggccatt gcggccagca aaatgacaat caggtacttc ctgtatcgca
     1561 taaaatcagg ggagtccatt gtatcctgtc ccgttttcct ttgaggagat gtttgtaccc
     1621 gttcatttta atcctttggc attacccaga aaaacggaac gatttcggga aataccgtga
     1681 gaggaaagag gtatttgatc cctgttgcca ttgcaggggg ggctgagtcc cgtctgctgg
     1741 ttcacggcgt cccgcagggt tgtcctgatc aatcaagaat tgaggtgtcg tcctgatagc
     1801 aaacgggttc ccaaaaaaac gcccccggcg ggaacgggct cttggagagg ttctgctgtc
     1861 cccctcgtca tgcgctactc gatgcattcc ctgataagtt cccgtgcacg agcggcaaaa
     1921 acgggataat caaagagagc tgccctccgc tggcatgcgt cccggaaatc gcaggaacgc
     1981 tctccgactt cgcgcacggc agtgcatatc tcgcgtggca cgggtgcaac gagcctcccg
     2041 cacgggccgt cgaggaccgt ctcctggtac ccgccctcgc gaaccgcaac gacgggcttg
     2101 ccgctggcca tggcctcaac gggcgtaatc ccgaagtcct cgtcaatcgc tgtggtgatg
     2161 aacccctcgc agcgggagta gagcgttctc atctcctcct ctccctgcac atgcttaaac
     2221 tccacgtttt ccggcgcgtt ccttacaagc tgctcgtaac cggggtatac cctccccaca
     2281 accaccagcc tcttttccgg catcatgcgg aacgcttcga cctggagttc cacgcgtttc
     2341 catttatcta ccctgccaag cgagagccag tacccttccg ggggctccca ggaaaaccgg
     2401 tccgcgtgga ccggggggta gaggacccgt gcatccctct ggtagacctt ctggatccgg
     2461 ttccggacgg tatgggatat gcaggcaatg tttctgacgt gctttctgac aaagcgcctg
     2521 tccatgtacc gggccagcgc aagcccgggc acatacactg ccttttccgg caggctcctt
     2581 tctgccagga aatagtagta catgtcatag agcgcccgcc tgggtgtcag catgtagtag
     2641 aggtggggga catgcctggc gaggtaccgg actgccatgt cgtcgatgca gatcacgaag
     2701 tcatagtcga gagatatttt ccggaaaagg cgcatgccaa tgacctgccg gagtggttct
     2761 gccggcagtg tgcagtcgag ggagcgaaac gggacggtgc gtccggggtc atagcgggag
     2821 acgatgtcct ccgaaaacga gggtacaacg acttcggccc cgagcgcccg ggcaagatcc
     2881 acgatcagcc tttctgcacc acccgtgaca gagaagtcac tcccggagag aatgcctgcc
     2941 ttcattcctt tcccccgagg gaactgcaga gggccatcca ttcttccccg atggactccc
     3001 acgtgaggtt tccggggatg gggtaggtag cctttccctc catgcgcagc aggatctcgc
     3061 ttttcaattc ctcgacggaa ccagggttaa taaaaaaggc gcctgcatag gaactcattc
     3121 cctcgaccag ccctccgact ctcgttgcaa tgattggcag tccgtatgcc atcgcgatgt
     3181 gtgcaacacc actctgtgat gccctcgtgt agggcaggac aaggatatct gctgccgaga
     3241 aaaaaacagg gacctcgctg tcgggcacgt acctgtttac aagggttatt ttgtccctga
     3301 ggggtgactc ctccgcaagc gaaagggatt ccctgtcttc ccaggcttcc ccgacgatga
     3361 ggagccgcgt tgactgaacc acggccggcg gaaggctttc gaatgcacgg atgaggtatt
     3421 tcaccccctt gtaaggtcgc aggagaccga aaaagagaat gacattctcc tcggtgatac
     3481 ccagctcctt cctggcctgc tttttcccga gggccggata ctggtcatac aagggatgag
     3541 ggatgactgt gattttctcc tgcggtatat ggtaagtacc catcacgagg tccctgtctg
     3601 cgcctgaatg gacgacaaag cgggtggcaa gccttcggat aatccttccg atgacgcggg
     3661 aatataccct gaccggaaga atcgactgtt cgagggagtc aacaacttca tggtactcga
     3721 tgatgaccgg tgtcttccgg gaaaggagaa tctggattgc gaggtacatg tgggcgacac
     3781 tggacgtcca ccattccagg accacgatat cagcacaacg ggaaatccgt gcagctttta
     3841 accacgtgaa cgggttatac cagtcaagaa gctctccagc atccacacct tccgcgaact
     3901 ttacggcggt caggttttgt cccacgcgtt tccagcccgg gaataatttc ctgggcagca
     3961 tgtggcggaa aagtactgcc ctcacggatg cttcccggga cagcgcgttg gccagtcgga
     4021 ccgtgtagta actgataccg gagaggaacc ggaatgacgg accgatgagc acgatacgca
     4081 ggggcctttt catcggcacc ccctgccatg aacccggctt gtcatttcaa cgatccggtc
     4141 cgggttcgtg gtgaccatgt ctcttcactc caccgtcacg ctctttgcaa ggttccgggg
     4201 ctggtcgatc tcccgcccca gtgcctctgc cgtcctgtag gcgaggagct gcaggaggac
     4261 cgtcgaacca aggacctccg agacgatatc ctcacccggg aggggtacga ggacgtccgc
     4321 gatgtcccgc agttcctggg actttccgtc cccgatgacg atgaggggca ctcctctggc
     4381 cttcatctcc ctgatattgg acaccatcgc cgggaaagac tctgcctgcg gacagagtgc
     4441 aaccacaggg gtcatcgggg agaggagggc aaagggcccg tgcttgatct ccccggcagc
     4501 gtatccctcg gcatggatat acgttatctc cttcatcttc agcgcccctt ccagtgcaag
     4561 gggaaagaac gggccccgtc cgacgaagaa gatggatccg gcctctttgc aaatatcgac
     4621 ggcaggtgaa aggtcttcca gcagtgcctc ccctatcgcc tcgtgaccgg aaaggattga
     4681 ctgcctaagc cggcccccgc tcgtcacatc cgcgatgtag aagaagacgg caagctcggc
     4741 gacaaacgac ttcgtcgcgg caacgctgat ctccgggcct gcccgcatgt agagggtatg
     4801 gtccgcaacg cgggttgcag tactgccgag gacgttcgtg atgacgagtg ttgcatggtt
     4861 gtgcatgcgt gctttcttga gcgcagagag cgtatcggcg gtctctcccg actgggtcac
     4921 ccccacgacg aggtcgtctc ccgggggagt gcggtacctg aattcagatg caatctcggc
     4981 acgcaccgga atcccgcagt attcctcgac gaggtactgg cagaggagtg acgcgttgta
     5041 agacgtcccg catgcaacga gcgtgatgcc ggagatgtcc ttcagaacgt cgggcacggg
     5101 ttctgcatac agtgccctta ccgtggtcga aaagaccgat tgctgctcgt atatctcctt
     5161 gagcatgtag tgggcaaagc caccgaggcg tacctcctcc acttcccagt ccactttccg
     5221 gacgggccgg tcggcccgtt ttcctccatg ccatatggtc ggccccgggg ggagaaggag
     5281 ggcaacatcc ccgtcctcga ggtaaatgac gcggtccgtg tgatccagca gcgcggtgac
     5341 gtccgatgcg gcgacacagg cacggtccgc gattccgaga accagcgggc tcccctgccg
     5401 tgccgcaacg atcccttcgt aaccttccgc aacggcaagg atggcatagc tcccctcgag
     5461 gcgggggagg atggctctca cggcggagag gagatcaccc ccggaatgtt cctcgatgag
     5521 gtgtgcaatg acctccgtgt ccgtctcgga tcggaaggta tggccgcgac ccagaagctc
     5581 ctgccgcagg gaggcatagt tctcgatgat gccgttgtgc acgattgcaa cggagccacg
     5641 gcaatcggtg tgggggtggg catttgtatc gctcggttca ccatgggtgg cccaccgggt
     5701 gtgccctatc gcggtcctgc ccttccgccg cgaaacaggg ggtttttccc gggaaatctt
     5761 acccttcttc ttccataccc agaggtcact gtcaaggacg gcgagtccga acgagtcgta
     5821 gccccggtat tcgaggcgtt tcagtccctc gatgacgagg ggggctgccc ttttctcccc
     5881 cgtatacccg aatatcccgc acacttttat accaccaggc cgccgtcccc catggctaca
     5941 gtggaggaaa tgtccctccc cccgcggatg accacgccgt tgcccacgat cgctgcccgt
     6001 agtgtcgaaa aaggcccgat cctgaccttt tcgccgacaa ccgctccgaa gaggcccttc
     6061 acctgttcct ctccgatctc gaggaggggg gctgccgtca cggtactgac gtggtcttcg
     6121 agctgtgacc cctccgcgat aacggcatcc ctgacaaggg agtgcggtcc gattacggcg
     6181 tcatcgagga tgatgctgtt ttcgaccaga caaaagggtc cgacccgtac cctgctcccg
     6241 atgctcgaat ggggcatgat gcaggcatgc gggccgatct cgcaccccgg cccgatgacc
     6301 gcaggaccaa gtatcgtgca ccccgggtgg atacgtgcac cctctcccac ccggacatgc
     6361 ccctggagga ccgtccctgc cgcgatctcc cctgcctttt cagcccggcc tttcctgatg
     6421 aggagccggt tcatcgaaag gaggtcccag ggatagatgg cgtcctgcca gtcgagcgcc
     6481 cggactgccc tgatcttcct gccagattcg aggaatgcac caaccgcatc ggtgaggtca
     6541 ggttgccgga tgtaatcgaa gaagtcgagg tcgagcgaga atatgccggt cgatatggta
     6601 aaaccaggag cctgctccgg tttttcgacg atgcgggtca cgtatcccct gcggatctcc
     6661 acaacgccga agttggaggg ataggggtgg tccttgacga ggactgcgtc cggcttgtcc
     6721 atgatacggg caatggacgc actgtcgatg tagttgtcgc cggggagaac gaggaaccgc
     6781 cccgagatgt gttcttttgc ctgcacgagg gcatgggctg tcccgagcgg cttgtcctgg
     6841 acgaccacgc gcacggggtg acccctgtcg ttgaggtggc tgatgacctg ctccctgcgg
     6901 tacccgacca cgacgatgat gtcgcggatt ccgcacgcga ggagggactc gatgacgtaa
     6961 tcgatgatgg ggacgtttcc gacggggatg agggccttgg ggcggctccg cgtgagaggc
     7021 cggagccttt ttccctcacc tcctgcgagt atgactgcct gcatcctgca cctacctgac
     7081 ctttgtcccg ggagcgatat aaccctctac caggcagtgg ggcccgatgg ctgcgccacc
     7141 gccgatgacc gagccgacgt tgaccgagca gttgatcccg aacatggcac cgtcgccgat
     7201 gatcgccccg aacttctttc tcatcgtcgg gtgccccccg acgtggacca ctgcacggtc
     7261 gtgccgcagg ttggcaacct tcgtccctgc cccgaagttg cagccgctgc cgaccaccga
     7321 gtcgccgagg taattgaagt ggggaaggtt cgtgccgggg aggatgatcg agttcttgac
     7381 ctctgtcgcg tgcccgatgt ggcacccgtc accgacagtc gtggcgcccc tgatgtaggc
     7441 atggggacct atccggcagt ctttcccgat gatgcaggga ccttcgatgt aacttcccgc
     7501 cctgaccact gatccctgcc ccacctgcac cgcacccttc aggactgcac cgtcttcgac
     7561 agtacccgcg attgcaggcg tgatgttctc catcatcttc tcgtttgcgg agaggaggtc
     7621 ccaggggaag cccacgtcga gccacgaact gacgcgtacc gcccgcaggg ctttattggc
     7681 aatcaggacg gagagggcgt cggtcagttc ccgctcaccc cgcggggaga gcccgacctc
     7741 cccgatgatg gggaatatat cctccccgaa atggtatatc ccggcattca cgaggttgcc
     7801 ggcaggttcc cgggacttct cccggaggac ggagacggtg tcgccctcga gctgcacgac
     7861 gccgtagtcc tcgggatggt cggaaggggc aacgcccatg caggccgggc cggcatcaac
     7921 gatgctgcgg atgtccccgg aggagaggac catgtccccg ttcatcagga tgaagtctcc
     7981 ccggacccat tcctccgcgg tcgcgagcgc atcggcagtc cccttctgct gcctctggac
     8041 cgcgtattcg attttcacgc cgaaactgct gccatctccg aaaaaccggc ggacttcttc
     8101 ctccctgtac ccgacgacga ggaggatgtc ggttattccc gcatcccgcg ctgcagcaac
     8161 gaggtgctcg agcatgggcc tgtttccgag ggggagcatg accttggggc gggtggacgt
     8221 gagcggccgc atccttttgc cctctcctgc cgccaggatg acacactgca taccaggtac
     8281 cctctcactc acgcgatatc tgttttttcc attttctgac ccggtcgagc ccctcgtcga
     8341 gaagtgcctt cgcggcagcc ggggttttcc cctccgccgt gacccttatt ctgggctccg
     8401 tgcccgacgc cctgatgagg aaccagcccc cgtccctttc ctccctgatg ccatccgtcg
     8461 ggacgcgagc cccgagcgca tgcaggactt ctgcggaccg ggggcagggg atggattcgc
     8521 ggaggacggt atagcgcggc aatgcatcga tctctgctgc aatgtcccac tctgacgcca
     8581 tccggcagaa gagggctgcc gcatacgggc cgtcgggaca cagcgactga cccggaaaga
     8641 tccacgctcc cgatggttca ccgccgaagt ctccgccgga caggagggcc tcggaaacgt
     8701 aactgtctcc gacgggtgtc cgcgtgacag ccgcccattc cccgattgcc atgctcgcgt
     8761 ccgtggtggt gacgaccttc cgtgccccca aaaaccgggc aaagaggacg agcagggtat
     8821 cgcccgggat gaacctgccc ctgctgtcaa atgccatcat gcggtcagcg tccccgtcat
     8881 gaataacggc cccatccatg tcccactggc ggacgagccc gccgatgtac gggagagcgt
     8941 cctttgaagg ctctgacggg cgcgggaaat gccccgtcgg gctgcagttg acggccgtca
     9001 catcaacgcc gatccccttc aggacgtacg ggctcacgac ggacccggcg ccccccccgc
     9061 agtccagtat catcctgacc ttcctcctgc agctgatccg gtcgacgatg cccgcaatgt
     9121 agggggtgag gatatcagtc tcgctggttt tcccaaaccg cgggacaacg gcagtaccgg
     9181 cagccctgcc gctctcacgg agccctgcct ctatctctgc ctgccgggcc cgtgtcagcg
     9241 acgctccgcc cggggaaaag accttcatcc cgttgtattc cgggggattg tgggacgcgg
     9301 tcaccatgca gcccaggcct gcctccggga ctgcacgggc cacagccgga gtcgggacga
     9361 gccccgcaga gaggatatcc gcaccgcggg agaggacccc cgctgccagc gcgtttgaaa
     9421 tgacgggaga gctggtccgg gtatcgtgac cgaggagaac ctttcccgtc ctctctccga
     9481 ggacgctgcc gagcgcaatg gcacagtcga ctaagtccct gccaaagacc gcccggatac
     9541 ctgacgagcc gaaatgcatc ggtaatcagt cgcagggcgg aaaaatagag ttatcctttc
     9601 ccgtaggggc accagtgggg caggttttcg agcgttgcaa cgccggccgt ggacggtccg
     9661 acgaggagga cgctgcctgc ccgttctccc ccgaaaaggt cgcaggcctc cggcgagatg
     9721 agcccttcgc ccccgacgag gacgacttct cccccgccgg ggacatcggt gtgccgcggg
     9781 aactgcccgg gcacgtgggg cgggatgtgc agtcccccga ccactctttc cccgaccttc
     9841 tcgatgaggt ctgccctgca tgcagcatgg cattccggtt cacaggacag gcgtgcccgg
     9901 gagatgcaca aaaacccggt catgacgttg aggatggcac atgcagcggc cctgtgcacc
     9961 gttttatcga gtgttgccct gaagagaaac gggagacgcg tggtcgccct cgtaggctcg
    10021 aacgtgacga attcagctgt tcttccacca aacgatgcct ccatgcaggc acctttttcg
    10081 aactggcaca cggttctttc ggggttgacc gagaggacga tgtttccgtc ctcgcacccg
    10141 catccgcggg tcagttcctc cagttttctg actgcgtcct ttacgatatc cattctatca
    10201 cgcttcaccg ggtgtcaccg aggaagaccc tgcacggcga cccgtcaagc ccctccagcc
    10261 ggagggggag cgccaccatc cagtattttc ccggtccgac tgccgagagg tcgaggaact
    10321 cgatcaccgt aatgccatgc ccaaggagcg tgcggtggac ggtgccgtcc ccgtcatacg
    10381 gctcgatgga aggtgaatcg attcccacgc acctgatgcc gagacctgca agggttgcag
    10441 cgcactgccg ggagagcccg gggtagtcat cccggaatgt gtcttcgccc gagtaccacg
    10501 tcctgaagag gaccctctct gtcccgggac ggagatcgca cgtcccgatc acgctctcct
    10561 ttcccggaac gctgacgacg gtgcactccc ccacgaggtt ttcgatcggt atcatgtcga
    10621 tggtcatggc accccggatg tagtgcgaag gggcatcgat gtgggtgccg ctgtgcgtgg
    10681 acaggcggag gtccgagagg aggtaccttc ccctgtcctc ctgccggaac gagggcacga
    10741 tgtccccggg atagacagcg ataccctcct tcaggggccg cgtcacgtca tggtaaacca
    10801 tttttcgcct agccctccca cccgtgctcg ccgacgaggg ggacgaacac gaccccgccg
    10861 taggacgtct tcgtgaccct gccctccctc ttttcgagtt tcacgagttc ctggaggtcg
    10921 cggcttccga ccggtgcgac aaggcgcccg ccctcggcga gctgctccac gaggggccgg
    10981 gggatcgccg gtgccgccgc ggtgacgatg attccctggt acggtgcagc cggcgggtgg
    11041 ccgcgtgtcc cgtcgcccac gatgacatgg acattcggga tgccggccct tttgaggttc
    11101 tcctctgcac tctttgcgac ctccggtatc cgctcgatgg aatagacaac ggcaccgagg
    11161 gttgcgagga tcgcggcctg gtacccgctc cctgcaccca cttcgaggac gcggtccccc
    11221 ggggagacag cgaggagttc ggtcatcagt gcgacgatgt aaggctggga gatggtctgc
    11281 ccgtgaccaa tggggagggg atgatccctg tacgcggcac ttgcgtaccc cggcggcacg
    11341 aagaggtggc gggggacctt gcgcatcgcc tcgaggaccc tcctgtcgct tatcccccgg
    11401 gcctctatct gggttgcgat catcgcctcc ctctcacctg cgtagggatc ttctgccacg
    11461 gcaaccacct cctccccgat ctctcttcct ttcccctaag gaatgtcccc ttcctcttca
    11521 aagtatccat cccgggccgg gagacggaac ggaaccctgc ctagaacccg ctcttttcgg
    11581 cggagtcgat ggctgcgtcg atctgggcct ggagggcgtc ggggagacct gctatcctca
    11641 cgtcgaggaa acccctgatg atggtcgcag tcgcgacgtc ctcgtcaagg ccccgtgaca
    11701 tcaggtactc gatctcgtcg cgggcgatct ttccgacggc agcctcgtgc gagagctcgg
    11761 tgtccacgac atcgcccttg atctccggga tggcatggat gaccccgtca cggaggatga
    11821 gccccctgca ctcgatgtgc cccttcgtgt gccgcgccgc accctcgatc atgccgcggg
    11881 agatgatcgt cccgcccgtg gtgatcgccc gcgtgaccag ctcggcgccc gacccctctg
    11941 ccgccagacg tgcaacggac ccgagatcca tgtacgaccc ctgggtgcac acgacgatgc
    12001 tgctgaaccg ggcaatcgcg ttccttcctg caagatcgac aaagggcgcc atctggacct
    12061 tcctgaccgg ctgcatgcac acgtagttcg agatgaaaac accatcctcc tccacgcggg
    12121 cggcgctccg cggaaagacg ctgatctcct cgccccagtt gtggatcatc gtcgaggtga
    12181 tgcgggcgcc cctgcccacg tagaactcgc tcaccccgat gtgcgacccg gtcttcgtgt
    12241 aggaggcact ggcacagccc gatatgatgt gcagctcggc accttcctcc gcgatgatga
    12301 tgttgtgcac gtgctgcacg gggctccggg caaggaatag gcatgcctgg agggggtata
    12361 tcgtcttgct ccccttgcgg gcgatgatca cgaacccccg cggttcgggc tggtccgcga
    12421 cgtacttcgt gtactggtcc ttgtcctttt tgacgaggtt ccatgaataa ccggagagcc
    12481 agtcgtactt ccggagcgcc tcgtggatgg gcaggatctc gattccctcg ttgagggagg
    12541 tccactgcct gatctcctgg tcgacctgga agaagctgcc ctccctgttc ttcatctcca
    12601 cttcaaggcc cgtcagggtc agcctctccc tgtcttcggg cgaaagttcg ctcatcttta
    12661 ctggatcttc tggcatgcaa ggcactcctt gtacccggat gtcttgatca ccttgaggat
    12721 ctcgcggggg ttcccgtggc accggaaggc accgtcgcac atcacgtgcc cgaagtctgc
    12781 atccaggtaa tcgaggatgt agcccgtgtg cgtgatgaca aggccgctct tcttcctgtt
    12841 cacgatgtgg acgtcctttt cgagcaggcg tgcaatcgcg tttccaatca gggtgatgtt
    12901 ctcgaggtcg accccgctct ccggctcgtc aagcatcacg aaatcgggct gctggaccat
    12961 gagctggagg acttcgctcc tcttgatctc gccgccggag aaaccgaggt tgatcgcacg
    13021 gtccatgaat gcatccatgt ggaggaaccg cgcgtactcg ctgaccatcg cggtccggtc
    13081 accggacgtg actgcaagga gcttgccgag cttgaggccc gagatggtcg gggggcgctg
    13141 gaagagcatc ccgataccca tcttcgcccg ctcgtggatg gggaggtttg tgatgtcctt
    13201 tcccttgaac cgtatcgttc ccttcgtgac gtcgagaccg gaaaatccca tgatggcacg
    13261 cagcagcgtc gtcttccccg acccgttcgg gcccatgagc acgtgcgtct caccttccct
    13321 gatggtcagg ttgatgtcat ggaggacttc cctgtccccg atcttcacat gcaggtcttc
    13381 tatctcgagc atctctttcc tcctggcatt cccttgctga tacatctcga ggggatagga
    13441 ttaaacggtt gtgaacgttc ccacctcctc atgccggcac gcttccccgg gggtccgatg
    13501 gatcccccac cgatgcaagc cctgcataca tgcctttccg gtcgaactgg tgcgaggata
    13561 gggtattata ggtatcgacg agccggttgt agcgggtgac aaggtcagag agccgggacc
    13621 gcatggtgtt gtactccgtt acccctgcat tgtaccgtgc aacgcgggaa ttatacccgg
    13681 ccacgttgcc atgcctcttc atcccctcca tctccaccct cagggcttcc agctccgatt
    13741 tcttatgcaa aaggtcctct tcgagatcac ggatgcgcac ccggagcgag tccgcttcat
    13801 cccccatctt ctccatggca cgggaaagag cccccgtctc cggacagcgg gtgtaattga
    13861 gtgtccccga gcccaccggg atgatggtcg ggaacgattc gaggcgtaca ccaccggcaa
    13921 gttcccgggg aggcacgccg acgaatgtga cgttcgttgt ctcgatatac gcataccccg
    13981 tgtgcctgta gcccgggccg ctgcacccca ccccgacggc catgtgggct tccggcccga
    14041 aatagaggag tgctgcccgg taaccctcgc gggcgagcag ggacgcaagg aggaggctct
    14101 tgtcatcgca gtcacctgca ccgtccacgt agacctcgac cgggaaccgg ggatcagagg
    14161 acttccgggt ctcgtacggg atggactgga cgaagaccgc gaggagctcg gcatactcgt
    14221 cgctgtcgag ggcccgggtg tcgcggacgc tccggagtgc agaaaggaga cccgcaaaga
    14281 acccttcctg ctccgggtcc tccatgaggg cacggtaaat tcctgccctc cattcgtcct
    14341 ccgtgatgtc ctggtcaaag atccgggcgc ccttgtccgc gttcctggcg cctgcataca
    14401 ccgccgcgtc caccggcacg tcgatggtca cggaatagtc ctggaaggga aacctgtaga
    14461 ccgggggccg gggcatggcc cctccctgca ccggaacgat ggaggggtag atggcaggcg
    14521 ggtgtgtcca ggggagcagg tcgaggcagc cggcaccagt catgaaaagt gcaattgcaa
    14581 ggacaacgga gagcagggtg cgcgtaccca ccccggtcac cccgttcccc tgccttccag
    14641 gtattcccgg agcgctgcta tggaggggag gactgccgtc ggcggtctcc tgcacgccaa
    14701 aagggcatcc ggcgagtatt tcccggtccg gacgaggatg cccgccatcc cggcgtccat
    14761 tgccccctgc acgtccgaga tggcgtcgtc cccgatcatc gccacctcgc cgggggcaag
    14821 gccgagggac gcaagggctg cgaggaaata ggattgtgca ggcttcccga cgagttctgc
    14881 ctgccgtccc gctgcgtact cgagcgctgc gacgaacggg ccggccgaga gggaaagccc
    14941 gtcgtcgtca cggaaatagc ggtccttttc gagggcgagc acgggggtgc cggcgatggc
    15001 aagccggaaa gccgcgttca gggtatcgta cgagaagctc ttcccgcagt ccccgacaac
    15061 gatgcagtcg caggcctccc cgcagggcac aatacctgcg cgcaaaaagt cttccttcac
    15121 atcctccgtc gtgaccagga acgcgcgtga ccatcccctc tgccgggcga gggatgctgc
    15181 cgcgactgcc ggcgtcaaga tgctgtccgg cccggcagga attcccatgc ccgtgagtct
    15241 ccgcgagatg ccctgaacag acctcctcgt gctgttcgag atgaaccgga aggaataccc
    15301 tgcctcctgc agccacgcga tcgtgcctgc cgcgcccggc acgggatcgc tgccggtgga
    15361 gatgaccccg tcaatgtcga tgagaaaacc acggatacct gccataccac accctttccc
    15421 tattcctgcc caatcctcgc gggttttaat cgggcaaccg gtgactgtac atttctcatc
    15481 cgcggcaccc atgatggttc cggcgcatgc ctgcttcccc atcccggtat tctcactttc
    15541 accccgcacg gtgaggtctc aagtgtatcc tctccagaat cctctcctgt ccatcccatg
    15601 acaatgccgc ttgtcttcga gactgccagc aggctctggc gggatcgcgt gaccgggtcg
    15661 caggaatact cggtcatcaa aaacgacagg ctccaccggg cattcctctc ccgctcccct
    15721 gtgcccgagt ccgagtaccg cgccgccgtc tcgtacagga cagcgctcct gcggatgttc
    15781 caggacagga ccctcgaaga cgtgttcccg gggcggtttg tcgcgacacc ggagggagac
    15841 acctactgca tatcccgcag gcatcccctc cccctccccc cgtgggacgg ggattcaacc
    15901 cgccgggcac tgcttgccga cctctcgctc gtctacggga tagggaagca tacgaaaagg
    15961 tacctgaaag gccggggcta ccggaccatc cccgacctcc tccagcaccg ccggttctcc
    16021 gctcccgccc gggaatgcct ccgggtcctg gaggagggtt cgccctgcga cgtgctttcc
    16081 ctcgtctccc gctggtaccc gccgtcccat tcccggcacc tcgcgtctgc ccggctcttt
    16141 gacctctccg acttcctctt cctcgatatc gagaccctcg ggatattcca aaggcccatc
    16201 atcctcgtcg gcgtcgcgtt cgtggagggc ggacggctcg caacagacca gttcctcgtg
    16261 cggtccatgg aggaagaact gcccgctctc ctcgcggcag gggaagccgt ccggaagaga
    16321 ggtgtcctcg tcacgttcaa cggcagggcc tttgacgtcc cctacctgcg ggagaggtgt
    16381 gcactctacg gcgggatgtt cccggctgcc gtgacccact tcgatgtcct gcatcctgca
    16441 aggagacttt tcgggcagaa atatccagac tgccggctct gcaccctcga acgggggctc
    16501 tttgggatca cgagggacca ggacgtcccc tccatgatgg tcccggaatt ctacgaggcc
    16561 tacgcgatcc atgacaaccc cggtccgctt gtccccatcg tggagcacaa ctgccaggat
    16621 ctcgtctccc tcgcccgcct cttttttcac ctcgtggagg ccgcatgaca gtcccgggag
    16681 atgctctccg gtccctccgc ggtgattccc gcctcgcgga cggctggatc catgcagagg
    16741 agataccccc gcgggaaccc cgttatggca cgccggaccc tccctttccc gggcagatac
    16801 aggagttcct cgattcccgg aaaatacgcc tctactccca ccagtgcgaa gcggcgcagg
    16861 cattccggga aaaaaagaac gtcgtgatga ccacccccac agcgtcggga aagaccctcg
    16921 ctttcgccct tcccgtcttc gaggcccttc tcacgcaacc gggctcgact ttcctcttcc
    16981 tctacccgac caaggccctt acccgtgacc agcacaagac gctccgtgcc ctcgaggagg
    17041 ggttttgcac gggcgcggtc agtgccgtgt acgacgggga cacggcgact tccgcacggg
    17101 cacggatccg gcaggaagcc cgtatcgtcc tctcgaaccc gtacgaactc cacaacatcc
    17161 tctcctggca ccaccagtgg agccagttct tctccgggct ctctgccgtt gtcatcgacg
    17221 aggcgcaccg gtaccgcggt gtcttcggtt cgcacgttgc cctcctcctg cggaggctcc
    17281 ggcgcgtctg ccggttccat ggttcccacc cccttttcgt cctctccacg gccacgcttg
    17341 ccaatgccgg gcagtttgcg gaaaaactct gcggagtccc gttcgagcag atcacgcgtg
    17401 acgggtcacc tgccggtcac cggacgatcg ctttctacaa cccctgcagg gagtggcccg
    17461 ccgaccggtc catgcaccgc gactctgccc tgatccttgc cctgtgcacg caggccggac
    17521 tgcagaccct ctgtttctcc ggatcgcgga gaaccgcgga gctcgtcgct tcgtgggcac
    17581 gggaattcgc agcggagcct ccccggcacg ttcctgcaga aaagattgcc tcttaccgcg
    17641 cagggtacct cccggaagag cggcgggcga ttgaggaagg tctcaagtcc ggtgcactcc
    17701 ggggcgttgt ctccacgaac gctctcgaac tcgggatcga tgtcgggacc ctcgatgccg
    17761 tggtgctctc cgggttcccg ggaacgatga tggcagcatg gcagcaggcc ggccgtgccg
    17821 gacgcggggc gcgtgacgcc cttgcaatcc tcgttgcttc ccccaatccc ctcgaccagt
    17881 acttcatgcg gcacccgtcc gcgttcttcg gcgccccgct ggagcacgcg atcatcgaca
    17941 tcgaaaaccc ctacatcctc tccgggcagg tcctgtgtgc tgcggccgag ctcccgctcg
    18001 actgcgaggc ggatcgcgac ctcttccctc cggccctccc ggaaatcgtt tcctcgctcg
    18061 ccgggcagca cctcctcggc cggacgcgcc ggggatggat ctacgcgggg agcaggcggg
    18121 ccgcagacct tgtctcgctc gaagggggtt cccgcgagac ctttacggtc atgtgcaacg
    18181 gtcacgtgct ggagaccctc gaccgggcac aggcataccg ggaagcccac aagggtgcaa
    18241 tcctcctcca ccagggcgag cagtaccggg tcgatgacct cgacctcgat gcgcggaccg
    18301 tccgcgtgac ccccgtaacc gtcgattact atacgcggcc ccagaagtcg gctgctgtcc
    18361 gggtgctgga ggtgaaggca tgcagggatc tttccggcgc ccgcctcttc ttcggggacg
    18421 tggaggtgac cgaacagtat accgcgtaca ggatgatcga gagggagact gtcatcggtg
    18481 tcgaacccct cgacctcccc ccctcccggt tcgcgacgcg gtgtctctgg ttcgagcttg
    18541 cccccggtac ctgcgatgcg gtcacccggg ccggcggtga cctcgccggc gggctccacg
    18601 ggatggaaca tgccctcatt gccgtcatgc ccttctttgt cctgtgcgac cgctgggaca
    18661 tcgggggact ctcggttccc tgcggcgggg agtcggggta ccctgcggtc tatatttacg
    18721 acgggtacga gggtggcatc ggccttgccg agaagggtta cgagatctgc gaggatattg
    18781 ttgcaactgc cggttccctc gtggcggact gcccgtgcac ggacgggtgc ccgtcctgca
    18841 tcctctcgcc caagtgcggg agtgacaacc agcccctcga caagaaggca gcgcgcctgc
    18901 tgctttccct tgtcctgact gcagggtaaa aaaatgagat gcgggaccct acttcctgtc
    18961 cctgagcacg cagatggacg caggttcccg tatcaggagt gcgaggctct ccgtgatcga
    19021 gaactcgaga ctgtcccccg cgggtccgac gtaccccacc atcatatcct ggccaagcac
    19081 gattgatgca taccgtttcc cggttgcgag cagcacaccc ccgctcttga ggacaggagc
    19141 cttgaagatg ccgtccgtca cgatggtccg gatgtgctcc agttcggtgc tctggccctg
    19201 gaggtatctc cggaacagaa ggttgtaccg cgccggggcc agcgcaaggg cataggggcc
    19261 gtggtacccg gcctcgtcga gggtaatcat tgcctggatg atgtcatccg cagctttgcc
    19321 cacggtgttc cacgaagaga gggcatatga ccctgttgcc tcgtgggtcg tcagacctgc
    19381 aatcccggcc gcaccctcaa agatgagggc gtcttcctgc cgggcacact cgatcgcggc
    19441 ctgggcagca ggggccgccg agaaggggag cccgttctgt tcataggaca cgatatcccg
    19501 caacccgagc gagaagcggg tagagaccat gtggacggga acgaactggc tcacggcaag
    19561 gcactcgctc acgcggcagt cctcgagcgg gacagccttg agaccaaggc cgtacggtcc
    19621 ctcgatctcg agaagtctcc gtcctgcaag gacactcttc gcggaatcga ccatcgcccg
    19681 gtcaagcagg gcccaggtct ccgcactgat cggggcatcg ctgcgcccca ggtagtggct
    19741 ggacatgtct ttttatcacc ccttcagcga cccaatcgtc agggaattgt cattcttctc
    19801 ttctgccatg ccggctccct ccggctttgc gcgttttgca atcccggcct cgacttctgc
    19861 tgccccccgg gcatagaact ccggttcgtc gggcgcaagt tcctgcagca gcctgagaaa
    19921 ttccccggca tgcacgcgtt cctcgttggc gatgtcgatg agcacttccc ttgcgagttc
    19981 gttgtcgatc gactcggcga gctggatgta catctgcact gcctcgtact cggctgcaac
    20041 catgagccgg atcgccctta caagctcggc ttgcgtgagc ttccggtcac tcttcatgac
    20101 agagaacggt gtactgaatt ccggcaatca catcactcca taaaatatct ggggcaaaac
    20161 cctcagtatc gccatccttc ttcattttat tttaaagtgc tggaaaaaga tcccggggac
    20221 gcgattgccg gaccatcgtg tgacccggga ccgtgcccgc aggagggagg agggcccggt
    20281 tttggattcg cccgttttac ccgtgttttt ttagtcccgg gaagtgccgg gattgtcctc
    20341 ttccctctcc cggaccgatc gcacgatctc ccgggaactg cagacggggt cacccctgta
    20401 ctgcccgatc ctgaccagcc ggggagaaag ccccctcttt tccagttccc ccctgatctt
    20461 ctcctcgtcg aagtgctggt cgtacccgaa cgtgatgaca tccggccgga tctcctcgat
    20521 gggccggaac atgtcatgga ggtcgccgag gactgcatgg tcgacgacac ggagggctgc
    20581 gaccattttt acccgctggc cctcggggat cacgggtttt ggcttgtgct tcacgttgcg
    20641 gtccctggca acgatgacat agagttcgtc accgaggcgc cgggactcct cgaggtagta
    20701 gaggtggccg gggtggagga tgtcgaacgt tccggttgca acgacacgcc tcatgccaca
    20761 acctccagtt ccgcaggtct gccgtccgcg tagaaacacc gccagctctc cctgtcgtag
    20821 ggatacccca cgatgaggtg gtaccgtccc gtccgcggga agaaggagag gtccgcctgc
    20881 gagggagaga gcactccgtt ggggtggctg tgcgcactcc cggcaaggtg cgtgtccagg
    20941 ggcatcatgt cgaggaagag ggttgcactc tcgccccccg tcaccgtccc ggggagaagg
    21001 gaaaactcgg agatgatccc ctcctcctcg cgcagcaccc ccgcgaattc acggggatgg
    21061 ctctccctcc ctatctccag caggaggtca agcagcgcac ggcgaatccc ccggatggtc
    21121 atgtacctta cctgtttgga cggtcaagtg caaaaaacga ttggcccgtg acgttcccgt
    21181 tcagaacggt ccgtcctgtt cgaagctcct gccgtaccgg atggcaagtt ccgccttgaa
    21241 gagctcggct ccgaggtagg cagcatggtc gaggagggag acgtcacccc ccgcaaggat
    21301 ggcagaaaag acgctgttcc atgacgttcc ccggtatgca gtgccgtgga tgacggcaac
    21361 gatctcgtcg ccctctatcc cgatccggaa gttcccgcgg gggtcatact ggatctcccc
    21421 cggagccggc cccgcccgga tgctcctgct gtactcgagg ggaggttccc gcctcctcct
    21481 cttctccttg atgaccagga ggtcgattcc caggtccttt gggtagggac ggtcccggga
    21541 aaggaccatc atctccgttg ccctgcgcat ctcgcggacc gatccgcggg tcttgtcgga
    21601 atgctcgctc gtgaagatga cagccgcccc gagttctgct gccatggccg caaggagcgc
    21661 gttctggccg atggagtctg cgtccaggag ctcgaccacg tttcctgccc cgaaaaagag
    21721 gggagtgtca tatccggaga accgcccgag ggccccgaca aggcccgacc ctgcaggggg
    21781 aaggatcggg tcggcgagca ggcactcgat acctgcactc cgtgctgctt cgaggttcgc
    21841 ggaaagcccc cgttctcccg gaacgaccac ggccgcgata ccggcatccg cgattgcctt
    21901 tcccgcgatc gggatgttat cttcctgcag gctcaaaacg aggtccgccc tcccgagggc
    21961 tgcctcgatc agggcagggt cctgggagtc aacggagagg gggccatcga tatcttccag
    22021 ctgcgagaag actgccccga catcccgtgg tgtcgcgtca aaggagaacc cgaggtccac
    22081 gatgtctgct ccacgggcaa aaaagtcctc aaccctcttc cggatgtcag gcacccggtg
    22141 agcgtccatg atctcggcaa ggaccttcat ccgcgatgtc ccgccgatcc ggacacccct
    22201 gatgacaaac gcacagtccg atgcagcctc tgccgccgcg atgcgggatt cggcctcttt
    22261 ccttctcttt tccacgagga aatcgtcagc gggaatcgtc cgcgagaggg tgatctccgg
    22321 caggagggag aggacgaaag ggaggtctgc cgcgtgacgg ggaccgaggt agacgggaac
    22381 accggttgcc tcctccacac cccggaagga cgcaacgcac atgccggaga cgatcaccat
    22441 gtcgtagtgg tcctccatga tgagtccctg cagctggtcc ggtgtcagga acgaggcgat
    22501 ctccccggtc acgaccacgc gggcgtcaag gccccgtgca gcgtcttcca ccactgcccg
    22561 ggttgccctg cccgtgggca ggaggatgcg cataaatctt cttaatatca cgcaggtcaa
    22621 aaagggtatg atcagatgct cgcgtgcgac ctccacatcc ataccgacca ttcccgtgac
    22681 ggggagagca gcgtggaaga ggtcatccgc cgggcagaag ctgccggact cgatgtcatt
    22741 gccatcacgg accacgatac cgtgagcggc gctttgcatg cgctctccat cccgacccgg
    22801 ctcatcgtca tacccggcac cgaggtttcc acccggcagg gacacctcct cgtcctcggc
    22861 ataaacgcac ccgtaccccg cggcctcgac atgggagagt ccatccggat tgcaaaggag
    22921 atggggggcc tggtcatcct cccccacccc ttccacatct ggcgccacgg tgcagggagg
    22981 aagatagacg cgtgggtccg cgacctcgat gcgatcgagg tcttcaacag ccgctacatc
    23041 gtgggctcgg cgaaccggaa ggccgagagg gttgccgggc ggctcggcaa gccctgcgtg
    23101 gggggatcgg atgcccacaa tgcccggttc gtgggatacg gcaggaccct cgtcgagagc
    23161 gagcgcagcc ttccggccgt cctcgatgcc atcagggcgg gaaggaccct tgcctacggg
    23221 aggatgactc ccctccggac ctacacccgc cagtcactga gaaacacatg gaagaggatc
    23281 tcgcacagga tcacccagag gtaacgcgac ttgcgttccg gtgcgggtat ataggtgaca
    23341 ggttttccgg gtcgcaggtc cagtccggtg cgcggaccgt cgagggggag ttcatcgctg
    23401 cctgcctgcg gctctcgctc ttcccggacc cccgggcagg ccgcttccag gccgcaggga
    23461 ggaccgaccg gggtgtccac gcgagggggc aggtcttctg catctcgacg cccttcccgg
    23521 accgcgcgat aaacctgctc cggtaccacc tgcccgccga cctctgggtg accggggttg
    23581 cccgggtcgc tcccggtttc catccccggc acggggcgat ccaccggacc taccgctact
    23641 tttttggcga gagagacctc gacgtgcaac cgatggacag ggcagcccgg gcattcgagg
    23701 ggactttcga tttctcgctc tttgcccgcc cggacgggag ggacccggtg cggaccgtcc
    23761 tctcggcccg ggtgtttgag gagtccggga tcgttgtgtt cgaggtccgt gccgaaagct
    23821 tcctctggca catggtccgg tacatggcat ccgctctccg cctcgttgga acgggggagg
    23881 ccgatgaaaa actcgtctcc tcgcgccttt ccggtgaccc ccggggcagg ctttcgcccg
    23941 cacctcccgg tggccttgtc ctctgggacg tatcctacgg gttccccttc gaccccctcg
    24001 acgccgggaa aaaggcacgc acgtacctgg aaagggaata cgtctcttcg cgggtgcggg
    24061 cctgcgtggc aggacacctc gcggacgatg cctgcccgtg tgacagcgtg gcccctcccc
    24121 gggaggagat cccgtgaccg cgtttccctg ctcgcgctgc gggaaatgct gcatgagcct
    24181 cgggaggcat atccgggtta tcaaaaccac gtctccccgt tcctttctca tcagcgtcgg
    24241 cgtcacccgc gagacgctcc ccgtgcagct cgtcccgtcc cttgtctccc tctattccca
    24301 aaaggaacct cccgcatggg aaaccgggtg gtgcccgttc ctccggcgcg aggccggcgg
    24361 tctcttttcg tgcaccattt acccgttccg cccgcgcatc tgccgcgggt tccggtgcat
    24421 gacgatgcgc atcctcgatc ggtcgggcca tgaagccggc cgggtgaagg gacgctcatc
    24481 gctcgtctcc gatgacccgc gtctcgtgga gctctgggat gatgccgttg cacccctcgc
    24541 aggtctcccg caaaaggagt ttgtctcccg gtgccgcgag atcctcgcgt cccacggctt
    24601 cgaagtggac atgttcgacg aatgagaggc agggttcagt ccgccatccg ggtgaaacgt
    24661 ctgcctgcct cttccgtcag gttgatgtat ttttgcgcat atgagaaata tatgtgcgca
    24721 agcacaggag gcacgaagta tgccaggacg tgacggaacc ggtcccctcg ggaggggacc
    24781 catgacagga tggggaatgg ggcgctgcag gccttccggt gttacccctg tccccccgca
    24841 ggcacagcag caggccgccc cggctggagg acagggcacg caggagccaa ccgggcagag
    24901 tcctgcaggt atcgcggctc cccggggtta ccctgtcgtg tatggccgtg gccgcggcgg
    24961 gataccatgg ggctgcggca ggggttttgg gagagggcgc tgctggcgct tcttccggtg
    25021 aatgcgcgaa tcctcctccg gaaccagcag aaaaaaaacg ggtgatggta tggctgacaa
    25081 aacgcggatg aagaacgaca tgtctccctc accttctcct caccactctg tcgccgggcc
    25141 acgggcaaag tccattcccc tccggacagc cctccggata gcgcgggaga ggcagagatc
    25201 acggtcctcg cggcgaaaga tattccgcga ggagcccgag cggtacctcg acattgtccg
    25261 gctgatgaag gagtccggcg ggatctaaag aggatcccgc ccccggggca gggcatacca
    25321 cggatccccg attgcccacc caaagattaa cctcatatcg gctgagatca aagaaagagc
    25381 acgggatcat ggcaacggat gttgtggcac ggggacccaa ccggaggcgg gggagaccga
    25441 ggatgcccag ggcactcgga gagcccctgt cgtcccggtg ctttgcaccc gagtgcgcac
    25501 cggacgagga gggcctcgcc atcacgctcc ttcccgagga agtggaactc ctgcggctcg
    25561 tcgacctcgg gggactcgaa caggaggagg ccgcggcagt cctcggcgtc tcccgccgga
    25621 ccgtctggag ggacctgcat actgcacgga ggaaggttgc cgaggccctg acgaccggca
    25681 agtgcctccg gatggacagg tgcccccgcg tggacgaggg gaagtgcccg cggaagtgcc
    25741 gcaggggcat gcaggagacc tgaacatccc ggggtccttc aaaccatttc tctccttttt
    25801 tgccgaataa ccgggacatg gtggtcttgc cggacaaatg caacaggttt atgccattct
    25861 actcatatga gaaataatag aggggcaggc aggacctgtc aggataccgg gatatttttc
    25921 ccggaactct cccgggacct ttcgcctgtc aggatgtgcg tgaggctgtc atgaaccccc
    25981 cgtttatttc ggtccggaac ctctccatgg aatactccgg gaaaaaagtc ctcgataacc
    26041 tctctttcga gatatacgag ggcgagacca tggggatcat cgggcgcagc ggcgcaggaa
    26101 agagcgtgct gatccacctc ctccgcgggg tggaagatcc cccgacagcg ggtgcgatcg
    26161 tttaccacgt gagcatgtgc ccgcattgtg caaccgtcgg gctgcaaagc gatgcaggca
    26221 aaccctgtcc gcggtgcggc actaccctcg gaaaggcaga cgtggacttc tggaaaccgg
    26281 aaaacgaggc cctgaaaaaa cagatcatgc gacgcaccgc catcatgttc cagagaacgt
    26341 ttgcccttta cggggatgac cgcgtcatcg aaaacgtcct gcgcgccctc gacgatgtcg
    26401 actacgggga gggtgcgatc aaccgggcag cggatctcct ggaccgggtc cgcctctcgc
    26461 accggatgat gcatatcgcc cgcgacctct cgggtggtga gaaacagcgg gtggtgctcg
    26521 cccgccagct cgcacgcgat ccccttctcc tctttgccga cgaaccgacg ggcacgctcg
    26581 acccgcagac cgcagccatc gtgcaccaga tgctccgtgc ggcatcgaag gactccggga
    26641 tgggaattgt gatcacctcg cacttctcca gggtcatcga ggacacggct gcccgtgcaa
    26701 tcctcctcga cgagggccgg atcgagaaga taggggctcc gggggatgtc atatcccatt
    26761 ttctgaggga ctatgcgcgc gaggaagatg aatctcccgt caccatcggg gaggatatcc
    26821 tcgtggcgcg ggacgttgcc aagcgctaca tgtctgccga caggggtttg atccgggctg
    26881 tcaacggtgt ctcgttcggg gtcaggaggg gagagatctt cggcataatc gggaagagcg
    26941 gtgcgggaaa gaccacgctc tcgcggatca ttgccgggat catcgagccg acggcaggcg
    27001 agatgaattt cctcgtcggg gacgagtgga tcgacatgac aaagcccggg atcgagaacc
    27061 gcggacgggc caagggatac atcggcctcc tccaccagga gtacgacctc tatccccacc
    27121 gcaccgtgct tgacaacctc accgacgcaa tagggctcga gttcccgaag gaactcgctg
    27181 tcaggaaggc aaagatcacc ctcgcgatgg ccgggttttc ggacaaggtg agcggggata
    27241 tcctctccaa gtacccggac cagctctccg agggagagag gcacagggtg gcgctggcac
    27301 aggtcctgat ccgcgaaccc cgcatggtga tactggacga gccgaccggc acgatggacc
    27361 ctctcaccaa gagggacgtc aagcactcca tcctccatgc ccgccaggag atggaccaga
    27421 ccttcatcgt ggtctcccat gacatggact tcgtccggga actctgtgac cgcgtcgcct
    27481 ggatgcgggg aggaaagatc gtggccatcg ggacagttcc cgaggtgctg cgtgccatgc
    27541 cacccgagga aggcgggatc tcctccgcgg gcgaggcccc cggccaggta acctgatacc
    27601 tccattcccg ggaccggctg aaatcatgcc aatcatcggc tttttcagcc agctccattt
    27661 ctttctgcct ttttttcggg aaaataccct tatgaatgat ggcctctaac ctgagtggct
    27721 gaagttccat gacggagatt ccccgggaag aatacatcct caagtgcacc tccgcgtgcg
    27781 ccgggtgcgg cgactccctt tccctccgct acgtcctcaa ggcagcagga cccgatacgg
    27841 tcctcgtcgt gcctgcctgc tgcacgagcg tgatacaggg catttacccg aacactgcct
    27901 tcaacgtccc tgtgtacaac gtggcgttcg ccgcggccgc tgcctgtgcc tccgggatga
    27961 gtgctgcact gcgtgccgcc ggaaagaaga cgaacgtcat tgcctatgca ggtgacgggg
    28021 gcaccgttga catcgggata caggccctct cgggtgcgtt cgagaggggt gccgacttcc
    28081 tctacatctg ctacgacaac gaggcatacg ggaacacggg gatgcagcgc tccggggcga
    28141 caccgctcgg tgcacgcacg acgaccacgc ccgcggggaa aatgcagccc aagaaggatc
    28201 tcgacgcgat cgttgctgcc cacaggcctc cctacatggc aacggcctgc ccggcgtatc
    28261 ccaaggacct gttccagaag gtcaaaaaag ccctctccta ccgcggcccc acgttcatcc
    28321 acatcctctc cccgtgcccg ccggggtggc ggttctccac cgaaaagacc gtggagatgg
    28381 ggaaactcgc tgtccgcacc gggatgtgga tcctgtacga gcgggagcag ggaaaggtca
    28441 cgatcaacgg accctcgaaa gcggcgatgg taaaaccgct ccctgtcgaa gaatacatcc
    28501 gcgcccaggg caggttcaag ggtatcagcg ctgaaacggt tgcccggatg gttgacgatg
    28561 ccgcggccct cgcccggcgc ctgcaaaagg aggaggaggg catatgctga cggttgcaac
    28621 cgggaacaag gctgttgccg ccgccgtgaa ggaggccgcg cccgcggtcg ttgcggcata
    28681 cccgataacg ccccagacag agatcgtgga gcagatagca gaatacgtct cttccgggga
    28741 gctcaaaagc cagtacatcc cggtggagag cgaacactcg gcaatggcag cctgcatcgg
    28801 ggcgagcgtg accggggccc ggaccttcac ggcaacgagt tcccacgggc tgcactacat
    28861 gcacgagatg gtcaactggg ctgcaggggc gcgtctgccg atcgtcatgg ccaacgtgaa
    28921 ccgtgcactc gggcccgggt ggaacatctg ggccgagcat accgatgcgt tccaggagag
    28981 ggattccggg tggctccagg tctacgtggg atcggtccag gaggcgttcg atgccgtcct
    29041 gatggcattc tgcatcgccg aggacgagcg tgtcctgctc cccgtgatgg tgaacctcga
    29101 cgggttcctc ctctcccaca cgatgcagcc gctggagatc gagaaagccg gggacttcat
    29161 cccgccgctc cacctcccgc atgccatcga cccgcaaaac ccctgcgggt acgggacgct
    29221 cacgggaccg gatgagtact tccggctccg ctgggatatc gagcggtcca tgcgggacgc
    29281 cgtggacgtg atccgcggga cgcaggagcg tttcgcacgc aggttcggga gaaaatacgg
    29341 catggtcgat gagtacaggt gcgatgacgc cgaggtcgtc atcgtggccg caggaacgct
    29401 cgggcgggag gcagaagtcg ccgtcgacct cctccgggac gaaggtaccc gggcagggag
    29461 catgcggatc cggtggttcc ggccgttccc gcggctcgac ctctccgggc gcgacgtcgt
    29521 tgtgattgac cgcgactact cgttcgggtt cgggggtgtc ctggcaaaaa gcattgccgc
    29581 aacggaaggt gccaagcctt tttccgtgat tgccggcctc ggtggccagg aggtcaccta
    29641 cgaggacata gcagggtttg tccggaacag gcagcccggc agggaactct ggttcggggt
    29701 gaacggcgat gtttgaagtc aggattcact cccgcggcgg ccagggcggt gtgaccgctg
    29761 cccgcctgct cgcgctcgcg gctgtccggg acgggaagta tgccaccgcg ttcccgtttt
    29821 acggtgccga gcgccgcggt gcaccggtcg tctcgttcgt gcggatcgac gatgccccca
    29881 tccgggtctc gagccaaatc aaaaagcccg acctcgtcat cgtgctcgac ccgagcgtga
    29941 tggacgtcgt cgacgtgctg caggggctca agcccggcgg ccgcgtcctc ctcaacgcac
    30001 gggaacgccg ggacatgaag ggttacccga cgtttaccgt cgatttgacg ggcatcgcac
    30061 tccgggaaaa actcgaggtt gccgggagcc cgatcctcaa caccccggtg ctcggtgccc
    30121 tcgcaaaaat gggaatcgtg accatggaat cagccaagtc cgccatcacc gagatgttct
    30181 ccgacccccg gaacgtgtct gccgcagagg cagcatacag ggagctggtc gcatgaaaca
    30241 gcgccgccgc ctcgccatca gccgcccgac aaccggcgcc tgcggcaaga ccgggtcctg
    30301 gcgcgtgttc cgcccgcgga tcgaccggga gaagtgcaac gcctgcggca tctgtgcaat
    30361 gtactgtccc gatgcagcga tcagcgagga ccttgagatc gattacgact tctgcaaggg
    30421 ctgtggcatc tgcgcaaacg agtgcccgaa atcggcaatc accatggaga gggaggaaaa
    30481 ataacccctc cctccctgcc ggggtccccg ggcgtcacgg taccggggcc aaaattcccc
    30541 ctctcccggg agagtgtgct ccggcagcca cccccaccct ctcgtttcct cacgtctctt
    30601 cttcgatggg gcactgggcg atgtattcga gactgaacgt gtaaaagtgc gtgaatccgc
    30661 agttcctgca gcgcaccgtg aagtggttgc acccgatgga aaggtcgtgg gggcccgtca
    30721 ccccgcagtt cctgcattgt gcatcggaaa cgagggtcca gaggtcgtag cacccgatcc
    30781 tcgtgaaact tcccggttta ctcacgtctt cgatgcgggg gacgaagatg cgggttgccc
    30841 cgcagttgct gcagatgacc tgggcctgga agggaaccgc cttgatgacc tggtctgcct
    30901 ccttcccgca atggtagcac gtcgtcctgt agcgcgtgaa gatgaaccgg tcctgcatgg
    30961 agtcagtatc gacccacgca gatataagtt tcccctcctc cacgtcctgc cgggacattc
    31021 cgggaaagtt tacggtattt ggagcgggat acgggcaaaa gcaatcaaaa aagggtactg
    31081 ccaattcccg ggaaaaagag tcgttggaaa aatggggggt ggggggactt tccggttctc
    31141 agaagtcgcc catgtcgccg cccattccac ccatgccacc catgccaccg gggcctccct
    31201 gcggccctcc tgcgggtggt gcactcttgg atgcggcgat cacgtcgtcg atgcggagga
    31261 tcatcgttgc tgcctcggcg gcactcgcga tcgcctgggt cttgactctc aggggctcga
    31321 tgacacccga cttgagcatg tcctcggcct tgccctcgaa gacgtttaag ccgtacgtct
    31381 tcttgccctt ctcgtgggct gcacggagct cgacgagcat gtcgatcggg tcgagccctg
    31441 cgttctcggc aagggtgcgg gggatgatct cgagggcgtt tgcgaaggcc tcgatggcga
    31501 gctgggcacg gccgccgact gttgcggcat actcacgcag gcgcagcgag agctcgatct
    31561 cgggtgcacc gccaccggca acgagtttct tgtcctcgta cacgaccgag acgaccctca
    31621 gtgcgtcctc gatggcacgc tcgagctcgt cgacgacgtg ctcggtcccg ccgcggacca
    31681 tgatggtgac ggctttgggg ttcttgcact cctcgacaaa gatcatctcc tcgccggaga
    31741 ccttgcgttc ctcgacgagg cctgccttcc cgagttcctc cctggcaatg gcatcgatgc
    31801 tcgagaccat gctcccgccg gtcgcacgga cgagcttctc catgtcgctc ttcttgaccc
    31861 ggcggatcgc gaggatgcct gccttggcaa ggtagtgctg ggcgatgtca tcgataccct
    31921 tctggcagaa gaggacgttt gccccggacg cgacgatctt gtcaacgatg ctcttgatca
    31981 tccgctcctc ttcgtcgagg aacgcctgga gctggtcggg gctcgtgatg ttgatctcgg
    32041 cgtcgacctc ggtcttcttg aactcgacgg gtgcattcag gaggaggatc ttcgcgttcg
    32101 tcaccttctt gggcatgccg gggtggaccc gctccttgtc gatgacgact ccctcgatga
    32161 tctcgcagtc atcgatcgag ccgcccactt tcttctcgac cttgatgtag tccttgtcca
    32221 cggtcccgtc ctcgtcggca accatggtga cggccttgac cacgaggtcg cagatcttgt
    32281 cgcgggagcc ctcggcaccc ttgccggtca tcgcggtctc cgcgatcttc ttcagcatcg
    32341 cggtgtcctt cggctttatg gtgaccgcga tgttctgcag gatctcctgg gccttctcgg
    32401 ctgcctgcct gtaaccgtgg gcgatcacgg tcgggtggac gtcctgctcg aggaggtcct
    32461 cggccctctt gaggagctcg cctgcaatca ccacggctgt cgtggtcccg tcgccaacct
    32521 cgtcgtcctg ggtctttgcg atctcgacca tcatcttggc ggccgggtgc tcgatgtcca
    32581 tctccttgag gatggtgaca ccgtcgttcg tgatcaccac gtcgccgatg gtgtcaacga
    32641 gcatcttgtc catgcccttc gggccaagag tcgtccggac tgcgctcgcc actgcctttg
    32701 cggcagtgat gttcatgccc tgtgcatcac gtccacgggt gcgtgaactt ccttctttca
    32761 ggatgagaat cggttgtcct ccgagttgct gtgacattgc tattcaccac gtgtagcgat
    32821 aaaattggtt tgtggttcta tataaaaatt gttatttaca gacgagctcg atcagttctt
    32881 ccccgtcctg gagcgtctgg aggcgctgtt cgccgatgac aagggtcttt ccgatcctct
    32941 tctgcttgtg gtagtcggtc agcacgcaca tggcatgcat tcccgtcacc tgggagatgt
    33001 ttcctatcag tgcagcgcgc ttgacaacct tctgggaaga gccgtacccc gtgaggatgg
    33061 actcgtccga tatctcgatg agggcctgga aaggagccct gtgcatggcg tggagcttga
    33121 cccctatcct ctccaggaac cccatgggcg actcctccgg cgcttctccc tcgtccgcaa
    33181 agacggatct gtacgcgagc aggtcgatgg cccggacgag gggtgcatcg aagatctcct
    33241 cgatcttctg ggcgacgtcg agcgtcgtcc ccatcccgct ctcgtacttg gagatggtcc
    33301 gccgcgagac cccgagcatc gagccgaggt caccgagcga gaggttcctc ttctcgcgga
    33361 gctcgcgcag cacgtcgccg ttgatgttga cgtagagccc gcccggtgac gcgtacacga
    33421 gcggggggac gccttcgacg aaggcatcgt acagtgtcgc gacgctgatg gcaaagatgc
    33481 cgtaccggac gtagactgca cctctctcga gttcggcgtc gcgtgccctc tccccgatga
    33541 tgaggggaga gcccttcagg taccgggcaa cgtggtcgag gtcccttgcc gtgtcctcgc
    33601 ccacgctgtc gatgtgggtg accgccttga tcacgaggat gacgttcttt ttcctcgcga
    33661 ccatgtcgaa gctccggggc ctcatgctga acttctccga gacccggaac ccacccatca
    33721 ggagcacgct cgtgaccgtc gagagaaggc gttcctggga cattccacta cgaatgggtt
    33781 ttccctgacc tgatataaat agtgatgtga tgggagggcc gatgttccgg atcgggatcg
    33841 acgataccga ctccccggcg gggatgtgca cgacgtacct tgcggccgtg ctttcccggc
    33901 ggctgaagcg ggccggcatc cgggtgttcg aggcccgcct ggtccgcttg aaccccaacg
    33961 tccccgaaaa gacccggggc aacgccgcga tatgcctggt tgccgggggg tccctccggg
    34021 tggccttcca cctcgcctgc gagaccgtcg gggaactcgc ggagatgtcc cacgagggca
    34081 cccatcccgg tgttgtcgcc tgcgaacgga tccctccccc ggacttttac ctgcgggccg
    34141 tcagggggtt ctgcacgctc gacgaggccc gggcgctcct ttcggaatgg ggggcgctct
    34201 ccaggggtta caagtcgggc cgcggcctca tcggtgccac ggcagcggtc tgcagccaat
    34261 tcgacgactc cacctgcgaa ctgctcgcct accgcaggag ggcccggttc gggacacccc
    34321 ggtccgtcga ccgggaaagc ctctttgcag cggactcttt cacgttcccc cacacgtggg
    34381 acaccgttga ccgggagaac gacatcgtgg tctgcgtgcc ccacacgccc gaccccgtcc
    34441 tcttcgggat acggggcgag cgccccgggt ggctcgccct tgcccgggag aaggtgattt
    34501 cggaggaccc ggcctgcgag cagatctttg tcacgaacca gggcacggat gcgcacatcg
    34561 tcccgggaac gatcggctgc ctcgaggagg ggcattccta catcgtcggg ggaaccgtgc
    34621 tctctctgcc ccggaccgcc cgggggggtc acgtctgcct caccctcggc aacgggaccg
    34681 ggactctccc ctgcatggcc tacgagccga cgcgggggtt ccgcgacatc gtccggtcgc
    34741 ttcgcccggg cgaccgggtg agagccgcgg gcagttacaa gaggggaagc ctcaacctcg
    34801 agaagatcga ggtcgtctct gcaccgcccc tccgcctcgt gcggccgccg atctgcgaga
    34861 ggtgcgggaa gcggatgacc agcgccggga aggggaaggg gtacaagtgc cggcggtgcg
    34921 gggggaggaa ggatgcaccc gaggaggtca tacagccccg cacggtctct cccggctggt
    34981 acgaggtccc tccgagtgca cggcggcacc tcgcccgccc gctctgcagg ggcgtccggg
    35041 aagatttcct ccgcctgcca cccccctgac gaaagggttg tcttccacgc atttccagcc
    35101 aaaaaatatc tcctttcccc tcgatacacc tttaccatgg aatgcgggga gtcagtcgag
    35161 cagatcgttc tccggccgaa aatgaccgtc ggggaactcg ttgcggccat gggccgggcg
    35221 ggagcataca acgggggcgc actggcgcgg gcggccgaca tctacgaggc gatgctccgc
    35281 gacaaggcgg tgacccggtt cgtcgggctt gcgggtgcga tggtccctgc aggcatgggc
    35341 aggatcgtca gcgacctcat cgatgccggt ttcgtggacg tgctcgtctc gacgggtgca
    35401 aacctcaccc acgatatcat cgaggccctc gggtgccggc actaccacgg gacggcctcc
    35461 tgctcggacg tcgcgctccg ggacgccgag atcaacagga tctacgatgt cttcctgccc
    35521 aacgagtcct tcatccggtt cgaggagttc atgcaggagc gcttcgggga ccttgccccg
    35581 caggcccccc tcaccgtccg gaagttcctc gcagaggtcg gtgcatcgct cccctcgggc
    35641 atcctcgcgt ccgcggcacg caacggtgtc ccggtcttct gcccggcact ggccgactcc
    35701 atggcgggac tccagtactg gctctacacc cagacgcaca ggcccatcct ggacgcgttc
    35761 ggtgacatgc aggacctgct ctccctctgt ttttcggcag aatcggcggg agccctcctc
    35821 gtcgggggcg gtgttcccaa gaactacatc ctccagagca tgctcatgac cccgaaagga
    35881 ttcgattacg cggtccagct gaccggggac cggcctgacc tcggcggcct ttcgggtgca
    35941 acgctggacg aggcccggtc gtggggcaag atcacggcaa gcgcccgggc agtgacggtc
    36001 tacggcgacg caacgatcac gctgcccctc ctcgtggctg cggtgcggga gaggctcggg
    36061 gtatgacgga tcttgtcctt gccctcgacg tgaccgaccc gcaacgggcc gtctctgttg
    36121 cagcggcctg tgccccgcac ctggacgcca tcaaggtggg ataccccctc gtcctccggt
    36181 cggggctctc cgttgcccgc gacctgtcct ccctcggcct gcccctcgtc gccgacttca
    36241 aggtcgccga catcccgaac acgaacaggc tcatcgccga ggcggtcttt tcagccggct
    36301 ttgaggggat catctgccac ggtttctgcg gggaggactc ggtcctcgcc tgcgtcgaga
    36361 ccgcgcacgg gcagggaggc cgctgtttcg tggtcgccga gatgagccac cccggcgcgc
    36421 tcacgttctt ttccgccggt gtcccggaga ggattgcccg gatggccgtc tccctcgggg
    36481 cagacgggat catcgcaccc gcgacgcggc ccgaacggat cagggccctg cgcagcatcg
    36541 tccgcgaccg cctcatctgg tcgccgggtg ccggggcgca gggcggcgac ccaaaggtta
    36601 ttgcccctct cgtggacggg atcatcgtgg gcaggcaggt ctaccagtct gccgaccccg
    36661 ctgccgaggc ggcagcactc gggttcctcc gccgatgatg agaaccgtga cctgacggga
    36721 tcatgtgccc cgtgatgacc cctatgagtc cctgaggcgg atctggccca aacaaagggt
    36781 ttaaatgcaa aaatggccat cgtattgtat gcaatggagc gaagaacagc ttattttagc
    36841 ccgatcactc cggcggctcg aagatattcc ccccgccgag cggcgttaca agtgccattc
    36901 ctgccacctc gtcgttgacg agacgccctg ccccgtctgc ggcgatacgc acctcgagat
    36961 catgtgtccc ctggaccatt gccactgttc ccacgagatc gtctccagca tcgagtactg
    37021 ccccctctgc ggcgccccgg tctgccccga gtgcgggagc cacgacgtcg tccagatcag
    37081 cagggtgacc ggctatctcc aggaagtgtc cggctggaat gccggaaaac agcaggaact
    37141 gaaagaccgc gtcaggtaca ccctcgccta gggtatcctc cccctccctt tcctgccggt
    37201 taccatgaga gcctccctga ccggcccggg caaacagggt cgcgtgcatc ccgttttcat
    37261 cctgccatga ggtattacat ccgcgacaac accctcttcc tccgcgggca cttccgcgcg
    37321 gcgggcacgg ggactcccgg ggggctccgc cccgtcccga ccatcgtcgt gcacggtccc
    37381 ccggctgccg gggatgaggc tgattccctg cggatcctcg agcgggccgt ccggagggag
    37441 gggcttcccc ccgacttttt cggggtcttt gcaggtgctc acccctcccg gctctgcatc
    37501 ctccagtacg attccctgat ggtcttcatc gcgccgggcc cgggggacgg atcgggcggc
    37561 ggcttttcga tcgtggtcta ttccggggag ggcctgagcg acgcggcact cctcggggca
    37621 ctcgtgacgg cgactgcggc acgcatggct gtcctgtacg ggagggatgg tgcgggaagg
    37681 ctggagagcc cgcaggatac cctcgttgtg gcatgcgagg gggaggtcgt ccatgccgat
    37741 gcatcaccct cgtccgcgat cgggttgcgc atcggcgagg ccgtccggtt cggcacgcgg
    37801 acggtgatgg agcggagtgc gggcagcagg ggtccggaaa agaggccgtc ctttttcatc
    37861 tacagccggt accaggggga tcactgggcc gagtgggtcc ctgaagagtg cccctactac
    37921 ccctgccatt tccccgggca gaggtgcgac ttctgttact gcccgtttta cccctgcggg
    37981 gatgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    38041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnttcccc gggcagaggt
    38101 gcgacttctg ttactgcccg ttttacccct gcggggatga aagcctcggc cagtgggtgc
    38161 agagttccgc aaagaacggt cttgtctgga actgcagcac ctgcacgctc ctccacgagc
    38221 ccgcgattgc agactacctg ctcgcccacc cggaggcatc gctccgggag ctcaaggcaa
    38281 agaaggcccg ggaaaaaaag tgaacggggt tatccctgtt ccacgccgag cgccgagagc
    38341 agctcgtcga gggggatccc gtgtgccatt gccgcttccc tgatggtctc gccccgggcg
    38401 atcgcacacc cgacgcaccc catgccgaac ttgaacaaaa cctctgcaga ttccggtttt
    38461 gtcttcaaaa ggtcgtaaat tgtactgtct gcagtaattc ccatggcata tacattattg
    38521 atagttgttt ataaatgtgc agcaccggga tcccagtttc accccccgcc cgattgcttt
    38581 atggtgaccc ggcggcctga gtgatctctt ggagatgtac gatggatttt tccgaaacgg
    38641 cagaaagaat ctcccagaaa gtgatgtccc acggccacgc cgtggaaaag accgcgatag
    38701 agaccaagct ccggcgcctc gtcgaggagt tcggtgtccc gctcgcagag gccgagcgga
    38761 cggtcacaaa cgagatggca cgcgaattct cgatttcggg gctccaggcc ggggggccgg
    38821 gcgaggcaaa gaccctcgat gcgctcgtcc ccggggaatg ggtcacggtg gaatgcaagg
    38881 tcgtcgccct gacagctccc ccctccccct ccatctcgca gaccgggata gccgccgacc
    38941 agacggcggc cgtgagattc gtcgtctggt cacgggccaa tgcacccgtc ctcaaggagg
    39001 ggaactggta ccggttcgag tcggcagtcg tggaccagta caggggctcg gtcaacctca
    39061 aggtccattc cggaacgacg atcagggaag ttcccggggg aggggccatc aagccggtca
    39121 tcaccccgat cgcggcactc cgccccggca tcgcatcggt ccggggcaag gtgatccagg
    39181 aatgggaggc cacgca
//
LOCUS       DAOOJU010000015        37094 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1223_length_37094_cov_15.844839, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000015 DAOOJU010000000
VERSION     DAOOJU010000015.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 37094)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 37094)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37094
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1223_length_37094_cov_15.844839"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(41..2092)
                     /locus_tag="PK679_05275"
     CDS             complement(41..2092)
                     /locus_tag="PK679_05275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HPC55405.1"
                     /translation="MNILVTPQKGDYRVLFLDNLKVVAVGIAEVEKTPRGYRPGRYRV
                     RWGGRQQFRHTPSKELVVSLRKGSVYLSGKDEAFEGFLKDFQIPYTITNVCRICLMED
                     RVTPLSRKNSVLYTTGERICFECGKRELRRELATMGKVGKGALGHLEELLSSLRDVGK
                     VLASVGPEKARISQALYDRLEAHPVQKTQALVELPLPRGFVDASGVEKLMPVQQMAVD
                     AGLLHGKHLLIVSATASGKTFIGEMAGLKNFMEGRGHCLFLVPLVALAVQKYQRFEER
                     YGKIAGVGLLVGQARINIPENRPAGDRNIRAPLVVGTYEGVDHFIRTGGTLPPIGTVV
                     IDEVQMLTDPDRGHRLDGLIARLKYLYPGAQFLYLSATIGVPKVLAKKLGATLVRYDD
                     RPVPLERYLLFLENKQKIPTIKRLCTQEYSRVSSKGFHGQSIVFTNSRARTHVIADAL
                     GPGYAAYHAGLTSQEKREIEAKFLSGKIKAVVTTAALGAGVDFPASQVIFDSLAMGIS
                     WLSVQEFGQMSGRAGRPDFHDLGKVVVLAEPGASYSRTSGITEEEVAMKLLRGEMEEV
                     APDHDLEQSSEEYVANAVVCRGKLADLEKINASMVGTMEPVLDVLVDKGLVKREDGRV
                     ALSPLARVMAEHFIGVERLLEVRELARKMEDPLDIVAELACADAERRKEKEKEKKRTK
                     R"
     gene            complement(2089..2898)
                     /locus_tag="PK679_05280"
     CDS             complement(2089..2898)
                     /locus_tag="PK679_05280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HPC55406.1"
                     /translation="MTATDTDPLSTLLRSKREVTRLQILVEIAEHQPAIRQQEVARKL
                     GVTPQAVSEYIRELVEEDMVAAHGRGHYSVTRSGIEWIQSQAEVLEAYARHIRRDVIQ
                     QVSTWTAIAATDLREGEPVGVYMQGGFLYASREPRSAMGTVVRDAREGEDVGVARLSG
                     LIDHTEGVIHVCKVPRIERGGSRRVRKDLLRDLVQDAAVVAAVGLEAYVALEQIGRKP
                     DMFFGAREGVIEAAFHGLECVIIIVDEEFTDFLKRLEGVGLSYTLHDLISP"
     gene            complement(2879..3394)
                     /locus_tag="PK679_05285"
     CDS             complement(2879..3394)
                     /locus_tag="PK679_05285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HPC55407.1"
                     /translation="MTGHIRIVNDPVDLIPLLITFHNATYKKVYDLLTRSWMTEEELC
                     AQVTDGDVGQCLMVLKKGSLIEEQWRMPVPGQKPSKEYRATYNKFRANFQCNFADLSD
                     LLFIAVSNDEYLRELVEKVEEELRSGNSSINDIARKFGVNPVFIKGLAKRIPHLDVKG
                     QGLVLLDRDRH"
     gene            3452..5680
                     /gene="hypF"
                     /locus_tag="PK679_05290"
     CDS             3452..5680
                     /gene="hypF"
                     /locus_tag="PK679_05290"
                     /EC_number="6.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003998 - acylphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HPC55408.1"
                     /translation="MRRSGRIKIRGIVQGVGFRPFVYATAKKLGIVGFVKNRGSEVEI
                     QAHGDRFEEFLAAVSRGPPMAEIDSVEVISDPGPFPDTFLIAESDRGSLSGMIPPDIA
                     TCAECIRDIGTPGGRYAGYWATSCVNCGPRYSIIRDLPYDRERTSMAAFPPCPACAGE
                     YGDPSSRRHHAQTIACAACGPALRLLDASGKEVPSPDVIRETARLLDAGSIVAIRGIG
                     GFHLACTEELAGELKRRLGRQEQPFAVMVRPDHVERIAFVSPEEMAALQGHERPIVVL
                     EKRDPEAHATISNLHTIGCMFPYTGLHHLLFSHLAHPLLIMTSANLPGYPMITEIDVA
                     MAKLHDMADFFLTHNRAIVNRCDDSVVRDGFIIRLSRGLAPKRTRIDLGDASILAVGP
                     ELNANVTVYRQGFCTTSPHVGNVRNPQTYAYLQETIATLCRFLGEGFEVIAHDAHPQF
                     LSTRYARELSHRWDATLVPVQHHQAHIAATTREECIGIAIDGVGYGTDGTVWGGEVFA
                     GSPAGYERVGHLEVVPMPGGDLATRFPERMLYGILPVPEVTALLAARGWTDVEITFLE
                     TQLDRNLNVVPTSSTGRVLDAVSALLGVCRERTYDGEPAMKLESFATGGKAVPWDLVY
                     RSDGGREVLSTRALVKRALSEAGKAGDRAGLRSVAASFQFNLARGIAGLAIHAAQERG
                     VPLVALSGGVAYNRSIRETIRAEVTKAGLAFHMNRGYPLGDGCISYGQCIVAGTLERE
                     GS"
     gene            complement(5949..>6596)
                     /locus_tag="PK679_05295"
     CDS             complement(5949..>6596)
                     /locus_tag="PK679_05295"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC55409.1"
                     /translation="ATPTATPTATPTATVTPTATPTATPTQPGQEPGYITVFSYPLGG
                     SVALDGTVIGTTPLQDYAVEPGTHTLTAAYPGYREYTTTVTVSPGEHKRVPLIIFMKG
                     IPTMFPTTIPTTSVTTNIPTAVPTATLTPTATVTGSTGTGALKISTVPRGATIYIDDV
                     VKGISPATISDIPAGNHELKVAKQNYKTTVKTVTVQAGKTIQVPLIVLSPTRSGF"
     assembly_gap    6597..6696
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<6697..7321)
                     /locus_tag="PK679_05300"
     CDS             complement(<6697..7321)
                     /locus_tag="PK679_05300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55410.1"
                     /translation="MYFTKWKETVILCACICLLAVPALATTVTVSPATIPDAGSSVDV
                     TIVADSLPTGLSGYIMTASVADPSVAEITAVTFPSWASMKLNSAVPASEVSLRASDLS
                     LGVSPGATGVTLVTLTVKGKIAGATTLGLTVRQMDPDGAGDPINPTVIPGTISVGGVV
                     PTATVTPTATPTATPTITPTATPTATVTLTATPTATPTATPTATVTPT"
     gene            complement(7336..11094)
                     /locus_tag="PK679_05305"
     CDS             complement(7336..11094)
                     /locus_tag="PK679_05305"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55411.1"
                     /translation="MLFVAVIVLLALAVSPATAGTSLSVDVSGLPLVFIQNEGQVSDD
                     VLYHANAPAHSIFFTKDAVVFTVGSGGISPASVEIALEGHSPGVVVTGEDKLGGKANF
                     FIGNDPSKWVRDVPTFGRVRYSNILPGVDIVYSGTQGVLKRDIVLSPGADPSALLFRY
                     SGQDDLALDTDGNLLVKTSAGTIREAAPVCYQERNGERVPVSCRYVLSGNGLVGFDTG
                     AYDPALPLVIDPYLDFSTYLGGSMDDRGYAVAVDSLGGTYVTGSTQSIDFPYPSWKAQ
                     YQEDPGGGLDAFVTKFEPDGLSMNYSTYLGGYYDDIGHGIAVNDSGYAFVTGETISPD
                     FPVLKAFQENISYSGTCCSSADAFITVLTPEGYDLEFSSYLGGNMTDIGQAIALTSSG
                     VAVIAGSTASDNFPTTTGAYDTTLNGTWDAFVTGISYDGSASSIANSTYLGGGNIDRA
                     NGIALGANGDIFVTGLTKSSDFPTLNAYRSSLSGGQDAFVTHFNPTAGSIISSTYLGG
                     TDEESGNGIAVDNTGAMYVTGFTRSMDFIKITSPPPHYQLQLKGLQDAFLTKLNPEGR
                     TVNFSTYLGGQLVEDGRGVAVDNMGSIFVTGYTDSLDFPVKNAVQSALNSYTYDAFVT
                     RFYPNGTALMYSTYLGGRLDDRAMGIALLDSNVTIVGYTESANFPVKNAVQPTLAGIS
                     DAFVARIASVPPVANFTAEANGVENYTLIRGLPPLLVNFTDLSTGEPTAWSWLFGDGN
                     TSTLQHPSHIYYTGNWTVNLTVSNLDGSNSTGKYEYIQVGDPLIVNFSANVSGVECTF
                     CQGQVPFDVNFTDLTNDAPIAWNWSFGDGNFSTDQHTNWTYHTPGLYDVRLTATNDYG
                     SKSITKFGIVEAGDVPTANFTANVTFGLAPLAVQFTDLSTAIPAVTSWNWTFGDGSPN
                     GTAKNPVHVFTAMGNYTVNLTVRNLYGNDTMSRFEYIRVGEIPVANFTADPVIGVEPL
                     NVTFTDFSTGYPAWWLWTFGDGQTENRTNNLTFNHTYLHAGNYTVSLTAGNEFGTNTM
                     TRSRYISVAGNATTVNLTFVPSSAIIPTNSTTAMKLVLEYAERGLSGYNITIFFTNAS
                     AADMVTFRPPSWLNESFVITSTVPAPSVWIKASDIDDVIRPGATNVELALFNSTGKTP
                     MTTTLDVTVSQIDTDTGDPVYTWVNKAPVQVVVLLPLPGYTNPPTDPFHDGVYWDVNG
                     NGRIDFDDVVQYFLYLEWIQENEPVSLFDYNNNGRIDFDDLYILFTMV"
     gene            11624..12124
                     /locus_tag="PK679_05310"
     CDS             11624..12124
                     /locus_tag="PK679_05310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HPC55412.1"
                     /translation="MLLANAVVGIIQLVIAIILAVIALYIGFSVLSRITKGIEEEKEL
                     AKGNAAVGIIVAAVFFAIALVVQSGVSGISLGVSKALSVGLFSMDGIVAIGVAILQLI
                     LGIVLAVGAIYLALSILDRLTKGVSEFEEIRKGNVAVALEMAGVIVATAVIIQSGVIG
                     VTSALL"
     gene            complement(12443..13951)
                     /gene="lysS"
                     /locus_tag="PK679_05315"
     CDS             complement(12443..13951)
                     /gene="lysS"
                     /locus_tag="PK679_05315"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HPC55413.1"
                     /translation="MENSDLAFEESRQEKVKELRARGIEPYPYVFPGRETIAAVRERS
                     AGAGHEKGTELFRVAGRLYTVRNHGKTIFSDLQDESGRIQLYIRKNDLGEEKFTLFET
                     CFERGDIVGVQGYAFRTKVGELTLWVEDITILSKALCSLPEKFHGLRDVEKRYRQRYV
                     DLIVNPDVRETFRTRSRIVAALRKFLGDRGFLEFETPILQPVYGGANARPFTTFHHYL
                     QQTLFLRIAPELYLKRLVVGGFEKVYEISRNFRNEDIDTQHNPEFTMVEIYEAYRDYT
                     DMMALCEGIISTITQEIHGKTLVAFGETSLDFTPPFRRMTMDGAVRELAGIDIWSHTL
                     EELQAIARDRGIEEWENAQNHREMLVVLFEGLVEEQLIQPTFIHDFPVENSPLAKRHR
                     SREGFTERFELFVAGMELANGFSELNDPVDQLGRFQRQEEKRKAGDLEAQMLDYDFIN
                     ALGYGMPPTGGVGIGIDRLVMLLSNRPSIKEVILFPQMKPEPGAGKKDETDA"
     gene            14213..14779
                     /locus_tag="PK679_05320"
     CDS             14213..14779
                     /locus_tag="PK679_05320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC55414.1"
                     /translation="MKVILLCGSPRPGGNTSQIVEECARVIQEKGLETEVFSLAGKKI
                     ESCTACNRCATEGNCVLEDGLADIIDAIRGAEGFIVASPVYFGTARGDVMAALQRIGM
                     VSRSTDRFLSWKVGGPIAVARRGGHTATIQEMLMFFLINNMIVPGSTYWNIVFGRDPG
                     ECWKDVEGMTTVRVFAENVARLITKISG"
     gene            14805..15800
                     /locus_tag="PK679_05325"
     CDS             14805..15800
                     /locus_tag="PK679_05325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC55415.1"
                     /translation="MESPPIIEVSSLFHSYGETEAVRGVSFSVREGEIFSLLGPNGAG
                     KSTVINVLITLLPLQKGTVTIAGYDLARDPAHVRRSIGIVFQEVTLDRDMTCREILEF
                     HGRLYQMPGAERKARIEELLALVELEGKADTLTRHLSGGMKRRLEIARGLMTRPRILF
                     LDEPTIGLDPQTRRRMWDYIRAVNGEGTTIFLTTHYMDEADSLSDRISIMDHGTIVTT
                     GTGWELKNRLGEDVIYLETSDNTRARDVLLGVPDVGDLGEKSHGLLATVRKDGTFLLP
                     VLIERLNSEGIRVNAVNLKKPSLDDVFVHYTGRELRDEGRGQETQHAGTAGGRSK"
     gene            15797..16639
                     /locus_tag="PK679_05330"
     CDS             15797..16639
                     /locus_tag="PK679_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55416.1"
                     /translation="MRQWTGFLTIYWRDMLRFFRFKTLLFSSLVQPALWLAFFGIAMS
                     ANFARLSSGMAPLPGIREVGYLTFMAAGVIALTTLFTSLFAGIVILFDKNWGLMREVM
                     ASPLPREHVIVGIGLSGMTKSFIQVSIITVFGILIGVEFFSGYTAVRILASLLGMFLF
                     VGIFSLGFVFLSSAIAASLESPEGLQGIMTLLSLPLFFVSNALYPAAAFPPALNALSA
                     ANPLTHLINGVRYFTIGPDFQVIGVHYAVTVQDMVLSFGVLVAFAAAMFGIALWRFGK
                     AVVT"
     gene            complement(16699..18861)
                     /locus_tag="PK679_05335"
     CDS             complement(16699..18861)
                     /locus_tag="PK679_05335"
                     /inference="COORDINATES: protein motif:HMM:NF012492.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HPC55417.1"
                     /translation="MDQRMDSEVFFGLHEALQDVLSHRLGWSHLREVQARTYRAVRTG
                     KDVLAIAPTAGGKTEAALIPVIDAILKEGRSGVACLYISPLKALINDQEERFLSFCIP
                     TGLDLKVWHGDVPRGDRSWDDGEPPHVLMITPESLEVLMGEKALARDLARTRFVIVDE
                     LHSFVESERGVHLRILLDRLNALAGSPVQRIGLSATVGNPAEVLAWFSGPRRGGEVVE
                     VLQPPREKKFSFSVQADPKRRTQVVAGLVAGKKALVFVNSRAEAEELGSALRGTVRHL
                     FVHHSSLSPQMRRAAEESLEGSESACIICTSTLELGIDIGDLDIVVQVGAPASVSSFL
                     QRMGRSGRRGGSPYMAFVLPDAWALLVSTAVIESARKKRVEPLIPKKKPYNVLVQQVF
                     LAVLRHRRTTAARIEKETGALPGFCDLPAGAVRELIAFLEREGFLVRDGEFLMSGPRM
                     ESLYGRSQGKDLYSVIQGGGEVRAVTPDGEQIGRLDARFVAGRGREGFSLGGRDWTLV
                     GRDDQHGLVVVVPGGETGGRAFWTGGQQAGLSPEVCRSVQRILGRGRTLLPLGPREEE
                     EIASCIASFPPLHSRGIHVWETGQGKKRDVVALTFLSRGRNALLALLARSVLGECTKV
                     RYDDISLLFPRVGGPGSADRVLEAFRKIQEMSVSGIEAAIPVPHPSAWKFGAALPPAF
                     LHEMAASDTWQVQEFAEEFGSLPLYRVQAPGEPAGPGS"
     gene            19197..20762
                     /locus_tag="PK679_05340"
     CDS             19197..20762
                     /locus_tag="PK679_05340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HPC55418.1"
                     /translation="MAVNVLLVASITLIYLVVILCLGYLGYKKTREAEDYLVAGRKAH
                     PVVIALSYGATFISTSAIVGFGGQAANLGMGLIWLTVFNIGVGILLAFVVFGKKTREV
                     GQRLRAVTFPDLMGKIYSSTFMQVVSGLVIVVGMPLYSAAVLIGGAQFIKETLGISYA
                     ASLIGFAVIVAIYVVFGGLIAVMYTDAVQGAIMLVGMTFLLILTYVILGGVTAAHSAL
                     TAIADMVPQKLAEQGMHGWTVMPDFGSPIWYTLVTTLVLGVGIGVLAQPQLVVRFMTA
                     KDNRSLNRAVLVGGPFILMMTGVAFTVGALTNVYFVNTQGKIAIAAAGGNVDAVIPLF
                     INLATPEWFTVVFMVTLLAAAMSTLSSLFHTMGTALICDLWGRGRECALSLKANQAGV
                     IAMIVASVVIAFLMPGSIIAIATAMFMGLCACAFLPVFAVAVYCKNPSPLAAKASLVT
                     GALVWFAWALFVNARYSAVFGLSSALIGKTSVLPFPWSAMDPLIIGLPLSAAVILVLQ
                     YLHRPEGAKAGLS"
     gene            complement(20892..21515)
                     /locus_tag="PK679_05345"
     CDS             complement(20892..21515)
                     /locus_tag="PK679_05345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HPC55419.1"
                     /translation="MPFLLGGIYYGLCFLFLPREPALLLGALMLAYVIPPAGKETVIP
                     LGIALGLPWWLVGTSMALLDVLAGLFMALNFDAALRIPLLGTWIKRFMGHGQEYLSRR
                     PWLQRFCFTGVVLFVMFPLQGSGGVGATLLGRLLGMQRWDVFWAIVIGAFLGCYLIAL
                     GSAFVWEMIVASPAIGISLAVGIIGTLAAAYLVYRWKMEKSVGPGHQ"
     gene            complement(21680..22216)
                     /locus_tag="PK679_05350"
     CDS             complement(21680..22216)
                     /locus_tag="PK679_05350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55420.1"
                     /translation="MARTGQKEKGEGGHDSGGNSDRLAELFSRPVFLSLTIGIPFCTF
                     KLLFGLTAFRVGASLPNGFLIVTGLAIAAWALADLIMNAGRALFDLVRREARFEYCTI
                     AQVGAFFGVPSVFLALDTLVTFLIISAMLWSGWIALLSPVEAWFWYAATTLNLVSLSL
                     VLLHAEIRRAGARGAEPR"
     gene            complement(22313..22888)
                     /locus_tag="PK679_05355"
     CDS             complement(22313..22888)
                     /locus_tag="PK679_05355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HPC55421.1"
                     /translation="MAKTRIIVALSGASGIVYGIRLLEAARELGLETDLIMTDLAARM
                     IGIETSLEPDQVNALATRVHDSFDFTSPLASGGIRHQGMVVIPCSMKTVAGIACGFSD
                     NLLLRAADCTLKERRPLVLVPRETPLSAIHLRNMLTLAEAGAVILPACPGFYHRPRNI
                     QGLVDHVVGKVFDILGIEHQLYRKWREGETT"
     gene            complement(23012..23431)
                     /gene="trxA"
                     /locus_tag="PK679_05360"
     CDS             complement(23012..23431)
                     /gene="trxA"
                     /locus_tag="PK679_05360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HPC55422.1"
                     /translation="MDDDELQRIREKRLRELEARLLEQKGKGQPQPARVLTVDESRFS
                     TLLAGHPRLVIDFWAEWCGPCRMVAPVIEELALEMAGRVTFGKCNTDHNPRLAARFGI
                     SAIPTILLFREGALLDRIIGAYPKETIRARIIRVFGL"
     gene            23559..23633
                     /locus_tag="PK679_05365"
     tRNA            23559..23633
                     /locus_tag="PK679_05365"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23594..23596,aa:Met,seq:cat)
     gene            complement(23745..25175)
                     /gene="purF"
                     /locus_tag="PK679_05370"
     CDS             complement(23745..25175)
                     /gene="purF"
                     /locus_tag="PK679_05370"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HPC55423.1"
                     /translation="MCGIVGIRDAGGVSFSIYYALYALQHRGQESAGISTFDGTRLFK
                     HKGQGLVAEVFDSTILESLDGNVGIGHVRYPTTGANRPENAQPFNFAFRDHVISIAHN
                     GNLVNGRQLRDEYECRGQIFCSTTDTELIAKVITEEMSNSGCIEDAVHRCMRVLRGSY
                     SVVMMIDGVLYGFRDPLGIKPLCLGRTPKGLIIASESVAIDALGGTFLRDVAPGELIC
                     IDGEGMRSMQIARASRRAHCIFEYIYFARADAVLDGALVYDVRLRIGAKLHEEAPVPA
                     DSVCPVPDSGTAYAVGYSARSGIPFMESLLKNRYMGRTFIMSTQTERERAVRIKLNPI
                     RKHLENGSVVLVDDSIVRGTTSRRIIGIMRDAGAREIHVRIGSPPIVAPCYLGVDMPT
                     REELIAHRRDEDEVRRHITATSLHHVTIDALVESIGIGRENLCMGCLTGTYPVDIPGE
                     VSSPVAVDFLDGTYQTRLEKFGTGKE"
     gene            complement(25186..25368)
                     /locus_tag="PK679_05375"
     CDS             complement(25186..25368)
                     /locus_tag="PK679_05375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L37e"
                     /protein_id="HPC55424.1"
                     /translation="MSKGTPSMGKRQKKTHIACRRCGSISYHVRHKTCSACGFGRSSR
                     LRSYKWTMKRPKVPTP"
     gene            complement(25388..25615)
                     /locus_tag="PK679_05380"
     CDS             complement(25388..25615)
                     /locus_tag="PK679_05380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HPC55425.1"
                     /translation="MTKRPLDILDQVLNRQPVIVSLKGGRELRGVLQGYDVHMNLVLD
                     KAEEIEGGQSRSVGTLIVRGDNVIYISPSLE"
     gene            25817..26314
                     /locus_tag="PK679_05385"
     CDS             25817..26314
                     /locus_tag="PK679_05385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HPC55426.1"
                     /translation="MARITPKKRHTLRKSQAEDLKNRLRAEIGDSTSLFPWEGIEIVE
                     TDGEVTLFLVGKKPLVMETKGIVFPTLRGLLEHPFPERKIVVDSGAVPFVAKGADVMR
                     PGITSISPDVRAGRPVQVVEEKYGKPLAVGIALLDAAPMQERETGKVVKTIHFVGDEI
                     WALEF"
     gene            26430..26801
                     /gene="sepF"
                     /locus_tag="PK679_05390"
     CDS             26430..26801
                     /gene="sepF"
                     /locus_tag="PK679_05390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HPC55427.1"
                     /translation="MVKFLDTLLGKSTPSSEDDYMDLDLEALEAEEEGAPALFVKIAS
                     VGDIKDSPRVKDEVYNGNIVIVDIAKLKADKVMYERVLKDLKEVAKDVNGDIIGLGDQ
                     RYVVITPNSVKISREKIGGVS"
     gene            26805..27356
                     /locus_tag="PK679_05395"
     CDS             26805..27356
                     /locus_tag="PK679_05395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011832524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZPR1 zinc finger domain-containing protein"
                     /protein_id="HPC55428.1"
                     /translation="MRKVVPGPCPVCNTEIEYIYQTEDIPYFFGLLIISTRCPSCGFR
                     FVDTQLMEHAEPSRWEFSVVSEEDLSARVVRSMNGTITIPELGVEIAPGPACEGFVSN
                     VEGVLDRVERVVESVILWAEDEDERGRARALREKIASARDGRFPVTLVIEDPTGNSAI
                     LDDRALVYPLTVEPDGENEGQET"
     gene            complement(27387..28388)
                     /gene="purM"
                     /locus_tag="PK679_05400"
     CDS             complement(27387..28388)
                     /gene="purM"
                     /locus_tag="PK679_05400"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HPC55429.1"
                     /translation="MGNGPPRTYREAGVDIDLEAEAISALVRNLSFRREGRFRMVSPP
                     GHFAGFVECGRYVLALTVDGVGTKMKVADRLRDWTTVGIDCMAMNVNDLYVMNIEPVA
                     FVDYIAADSLSVEQMAQIGAGLNEGARQANVSIVGGETATLKGLVNGLDLAGTCLGIQ
                     EKERVICGGKIRPGDVIIGVASSGIHSNGLSLARRIVESLDAWDERLSSGRTIARELL
                     VPTRIYREALDVASETEVHGMCHITGGGLLNFTRLSRYGFDITDPMPPHEIFTWIREK
                     GKIGTVEMYRTFNMGMGYAYIVPGPSVDAVLSRVEGSRVVGSVSETPGVRLAGTPIQ"
     gene            complement(28381..29769)
                     /locus_tag="PK679_05405"
     CDS             complement(28381..29769)
                     /locus_tag="PK679_05405"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HPC55430.1"
                     /translation="MKFGGTSVADGGSVSRVVDIVESCYRAGNEVAVVVSAQRGVTDQ
                     LIAIASELANNHNSDEIGRFINSLRVRHGKVLLETAEDYADEVGILLEEQLCNLENIL
                     TAVHNLRELTPRSRDYIITFGERLNSLVVSAALKQRGIPSMILDGCEAGIVTTASHGE
                     AVAIPASEGKIKSRVLPLLTNTVPVIMGFMGCTEKGVVTTLGRSGSDYSAALIGAAID
                     ADEIVIWTDVDGIMTSDPRIINDARVIPVISYHEVMELSYFGAKVMHPRSIEPAMKKD
                     ILVRVKNTFNPDHPGTAIVRGQKRDSRVVKALTYIEKVALVNICGAQMIGRPGVAKAI
                     FTLLADRDINVMMISQGSSEANISLVIDESQEDAAKEALSVLVAEGRVREVTTNSDVC
                     AVAVVGAGMAGARGTGGRIFSALGNGGVNVMMISQGSSELNISFVVTKADGPKAVRIL
                     HDEFRLSEEDNG"
     gene            29843..31468
                     /locus_tag="PK679_05410"
     CDS             29843..31468
                     /locus_tag="PK679_05410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit A"
                     /protein_id="HPC55431.1"
                     /translation="MRSAEVLDCHVLVIGSGGAGVRAAIEASGYGETILVSKTLAGKG
                     GCTTMAEGGYNAVLREEDSCGIHFEDTMKGGAYLNDPELVSILVAEAPQRINDLLAWG
                     AVFDVTDSCDVAQRPFGGQTFPRTCYAGDRTGHEMMMTLIERLASTNVEIENEVTALD
                     LVREGERVVGALCLDGKGEVMVIRADATVLATGGGTQIYDISTNSSSGTGDGFAIGYR
                     AGAELIDMEMVQFHPTGAVYPYDARGRLITEAVRGEGGILRNAAGERFMSRYDPERME
                     LSTRDVVSRAIATEILEGRGTPHGGVFLDVTHLPRQQVEEKLPVMLEQFLKFGVDIRE
                     EPMEVAPTAHHVMGGLRITPDAGTTVPGLFACGEVTGGVHGANRLGGNALADTQVFGK
                     RAGESAGRSPRRDSRIDPKAIEAQEERLAAFLDGHVPPSTVIRSLKTAMWEGAGIFRT
                     EAGLNKTLGVISHLSSLRLLARTRENLAGCCTAQNMLLSASLVVRGAILRKESRGAHM
                     RKDVVQTWDARNSPYGHTYQSLDRSGIETAVRS"
     gene            31465..32934
                     /locus_tag="PK679_05415"
     CDS             31465..32934
                     /locus_tag="PK679_05415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="HPC55432.1"
                     /translation="MKKIHVRVFRYDPEGDARPHYQNYVVEVNEGARVLHVLQAIHDE
                     IDPTLSFRYCCGAGQCGSCAVRINGVPGLACMEEARDDMTVEPLDLPVKKDLVVDLLP
                     YLNTLPRIQPGGEAFVPDREKVELIKPLRSCIECLCCVSVCPAMDVTRFDGPAAMRQE
                     QRLALDPRDRRDRVTEAVSRGLFACTSCQACWKVCPKDIEIPGKAIEKLRALANRKGL
                     TLPRHQEVARLIRESGRSIVRTGPTFLEDAPEVIEPDGPVRATVGFFVGCMYNGRLPA
                     TARDAMAVLKRNGIRVIIPREQVCCGSPLIRTGQIDFIDTLKKRNIDAFVFRNIDTVL
                     TMCAGCGSTLKNDYRTPFRVMDINEVLTKFGIEAPARLPIRVTYHDPCHLLRGQGIRD
                     EPRELITQVADLVEMPSVCCGSGGGVRSGMPDVASALGENRRKEIEKTGAEIVVSSCP
                     FCEFHLSEHTDRPVRNVTSLLLEGYREKDRKKAEQQVQG"
     gene            32998..33438
                     /locus_tag="PK679_05420"
     CDS             32998..33438
                     /locus_tag="PK679_05420"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC55433.1"
                     /translation="MYTFLLAASHTDTTGLSRHLDVAGLEIYADPLLEKVFFFLIENV
                     VRYGGGATEISLSSCESPEGLILSFEDNGSGIPDEEKAALFETVIGKERGFLLFLARE
                     ILSITDISLRETGEHGKGTRFEIVVPRGGYRFAGQNPPQFSRDA"
     gene            33577..33801
                     /locus_tag="PK679_05425"
     CDS             33577..33801
                     /locus_tag="PK679_05425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55434.1"
                     /translation="MTNPWLPYKMPPLRAYILAPGVVQIEDIVYNLPAGTVERGRPRP
                     DNPEFIVPVKENSESAARAAMEGLYRIVFD"
     gene            complement(33959..35146)
                     /locus_tag="PK679_05430"
     CDS             complement(33959..35146)
                     /locus_tag="PK679_05430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55435.1"
                     /translation="MALGKAAYLKSITRPAMGTSRPVGKTLEGATPPSVFVGSWNYPR
                     VFAGPLVAPVREECGIMDTPESWIPSGWTQEQILACRLDLVRGKRAHDVFRVEDPFAL
                     RLQEVVLSSSSLESEVSFLHAPTGVSLSEEFTPYGPSAPLENFRADSGRFDPHLERCY
                     YDRDLCAADAIIDLHRKGVPFSRIQKALSTGALGQGKRRRLVPTRWSITACDTVLADF
                     YLRQVRQNSIIDTVRVHEFSSLNNHYAVILLPVPWEYEWMEAFLRVRGNEEVIFSDHE
                     GPGGKREYSSVGGCYYSCKMAVLEALAREGLQAGAIVLREAGAGYIPLGVFNVRENVR
                     QAMQQPYREFEDLAGALADVAGRMTLSPERFIAESTLLAEMLRSRQTTLDQFLVDSRP
                     GPA"
     gene            complement(35209..35760)
                     /locus_tag="PK679_05435"
     CDS             complement(35209..35760)
                     /locus_tag="PK679_05435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55436.1"
                     /translation="MKEEARKLVHLCFGAAIAGAVFVFPREQAILLLAGSLLPGLILA
                     ELVKTGHRVPLISFLVARLEREGEFPGKGAIYFVVSSLFCVAFFPSAMAAAGVLSLAV
                     LDSVSALAGLRFGKTRVNGRKTLEGFLAGVAANSLVLCAFLDPVRATLVSLVAGAVEL
                     AVPLDDNLLIPPAACLFLSLVGM"
     gene            35866..37092
                     /locus_tag="PK679_05440"
     CDS             35866..37092
                     /locus_tag="PK679_05440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HPC55437.1"
                     /translation="MTVLDTPAGEILQENATTVEHLDIRGTRVERIHGEFWTSGQRQA
                     SSIHEISYRGCFKPQLPAFFIERFTREGDLVYDPFSGRGTTVIEAGLRGRRVAANDIN
                     PLSCILTRPRFFPPDLPGVAARLSGIPCRDCRQDTAPDLSMFYHEKTEAEIVSLRDYL
                     LSREREGSLDYLDEWIRMVATNRLTGHSAGFFSVYTLPPNQAVSPERQAKINRERGLV
                     PEYRDTKALILKKTRSLLRTVTPGERERLRAAGESGLFLSCDARNTPRIPDCSVQLTV
                     TSPPFLDVVQYSKDNWLRCWFCGIDTEATERLMTVTRSLTEWKRVMQQTFLELFRITR
                     EGGYVAFEVGEIRRGTLCLDEVVVPLGVRAGFSCEGILVNTQHFTKTSHIWGVDNNSS
                     GTNTNRIVVFRKGSEG"
BASE COUNT         7170 a        11166 c        11100 g         7558 t
ORIGIN      
        1 cccccctccg aaatgacgga tgatgcgttt tatcaaaaaa ttaccttttc gtcctcttct
       61 tctctttctc cttctccttt ctcctctccg cgtctgcaca tgcaagttcg gccacgatgt
      121 cgaggggatc ctccatcttc cgggccagtt cccggacctc gaggaggcgt tccaccccga
      181 tgaagtgctc ggccataacc cgtgcgagcg gcgagagcgc aaccctgccg tcttcccgtt
      241 tcacgagacc cttgtcgaca aggacgtcga ggaccggctc catcgttccc accatggatg
      301 cgttgatctt ctccaggtct gcgagctttc ccctgcagac cacggcattt gcgacgtact
      361 cctcggagct ctgttcgagg tcgtgatcgg gtgcgacctc ttccatctcg ccccgcagca
      421 gtttcatcgc gacctcttcc tctgtgatac ccgacgtccg ggaataggaa gcccccggtt
      481 cggcgagcac aacgaccttt ccgaggtcat ggaaatcagg ccggcccgcc ctgcccgaca
      541 tctggccaaa ctcctggaca gagagccacg atattcccat ggcgagcgag tcgaagatga
      601 cctgggatgc cgggaagtca acccccgcac cgagcgccgc agtcgtgaca acggccttta
      661 ttttcccgga cagaaatttg gcctcgatct cgcgcttttc ctgcgacgtg agccctgcgt
      721 ggtacgccgc gtaaccgggg ccgagtgcat cggcgatcac gtgcgtcctc gcccgggagt
      781 tcgtaaagac gatcgactgc ccgtggaatc ccttcgagga gacccgggag tactcctgcg
      841 tgcacaggcg cttaatcgtc ggtatcttct gcttgttctc gaggaaaagg aggtaacgct
      901 cgagcgggac gggccggtcg tcgtaccgga cgagggtcgc accaagcttc tttgcaagga
      961 ccttcggcac cccgatcgtt gccgagaggt acaggaactg ggcgccgggg tacaggtact
     1021 tgagccgtgc gatgagcccg tcgagccggt gaccccggtc agggtcggtg agcatctgga
     1081 cctcgtcgat cacgactgtc ccgatgggcg gaagagtccc cccggtacgg atgaagtggt
     1141 ccacaccctc gtacgtcccg acaacaaggg gtgcccggat gttcctgtcg ccggccggcc
     1201 ggttctcggg gatgttgatt cgtgcctgcc cgacgaggag gcccacgccc gcgatcttcc
     1261 cgtaccgttc ctcgaacctc tggtacttct ggacggcgag ggcaacgagc ggaacgagga
     1321 agaggcagtg tcccctcccc tccatgaagt ttttcagacc cgccatctcg ccgatgaacg
     1381 tctttccgct cgcggtggca gagacgatca ggaggtgttt tccgtggagc agccccgcgt
     1441 cgactgccat ctgctggacc ggcatgagtt tttcgacccc cgaagcatcc acgaacccgc
     1501 gggggagggg cagctcgacc agggcctggg tcttctggac ggggtgcgct tcgagacggt
     1561 cgtagagggc ctgcgagata cgggccttct ccggtccaac ggacgcaagg accttcccga
     1621 cgtcgcggag cgatgagagg agctcctcaa gatgcccgag cgcccccttg ccgacctttc
     1681 ccatcgtcgc aagttcccgg cgcagttccc tcttgccgca ctcgaagcag atcctctctc
     1741 ccgttgtgta aaggacgctg tttttccggg agagcggcgt gacccggtcc tccatcaggc
     1801 agatccggca cacgttcgtg atggtatagg ggatctggaa gtccttgagg aacccttcga
     1861 atgcctcgtc ttttcccgac aggtaaacgg aacccttccg cagggagacg acaagttcct
     1921 ttgacggcgt gtggcggaac tgctgcctgc cgccccaccg taccctgtac cgcccgggcc
     1981 ggtatccccg cggggtcttc tcgacctccg cgatcccgac ggcaaccacc ttgaggttgt
     2041 ccaggaagag gaccctgtag tcacccttct gcggcgtgac aagtatgttc atggagagat
     2101 gaggtcatgg agtgtgtagg agagcccgac accctcgagc cgcttgagaa agtcggtgaa
     2161 ctcctcgtcg acgatgatga tgacgcactc cagcccgtgg aatgcagcct cgatcacccc
     2221 ttcccgggca ccgaagaaca tgtccggctt cctcccgatc tgctccaggg caacgtacgc
     2281 ctcgagcccg acagcagcga caacagctgc atcctgcacg aggtcgcgga ggaggtcctt
     2341 tctcacgcgg cgggacccgc cccgctcgat ccgggggacc ttgcagacgt ggatgacccc
     2401 ctcggtatgg tcgattaaac ccgagagccg ggcgacaccg acgtcctcgc cctcccgggc
     2461 atcccggaca acggtcccca tggcactcct cggctcgcgg gacgcgtaca ggaaaccgcc
     2521 ctgcatgtag acaccgaccg gttccccctc gcggaggtcg gttgcagcga tcgcagtcca
     2581 ggtggagacc tgctggatga cgtccctcct gatgtggcgt gcatacgctt cgaggacttc
     2641 ggcctgggac tggatccact cgatcccgct ccgggtcacg ctgtaatgtc cccggccatg
     2701 ggctgcaacc atgtcctcct cgacgagttc ccggatgtac tcggagactg cctgaggcgt
     2761 gacccccagt ttccgggcga cctcctgctg gcggatggca ggctggtgtt ctgcgatctc
     2821 gacgaggatc tggagtctcg tgacctcccg cttgctgcgc aggagcgtcg agagcgggtc
     2881 agtgtctgtc gcggtcaagg agaaccagcc cctgcccttt cacatcaagg tggggaatac
     2941 gcttggcaag tcccttgatg aagacgggat tgaccccgaa tttccgtgca atgtcgttga
     3001 tcgacgagtt cccggaacgg agttcttctt ccaccttctc gacgagttca cggaggtact
     3061 cgtcgttgga gaccgcgatg aagagcaggt cggagaggtc ggcgaagttg cactggaaat
     3121 ttgcccggaa cttgttgtat gtcgcccggt actccttgga cggtttctgg ccgggaaccg
     3181 gcatcctcca ctgttcctcg atcaggcttc ccttcttgag gaccatcagg cactggccca
     3241 cgtcaccgtc tgtcacctgg gcacagagct cctcctcggt catccaggac ctcgtcaaca
     3301 gatcgtagac tttcttgtag gttgcgttat gaaaagtgat gaggagggga atgaggtcga
     3361 cgggatcgtt gactatcctg atatggccgg tcactgctaa aaccctatta ttatatggcg
     3421 tgataaatca ataaatcttt gtttgaaagg catgcgcagg agtggacgga taaaaatccg
     3481 cggaatcgtg cagggggttg gcttccggcc ttttgtgtat gccaccgcaa aaaagcttgg
     3541 catcgtcggt ttcgtgaaaa acagggggag cgaagtcgag atccaggccc atggcgaccg
     3601 gttcgaagag ttcctggcgg cagtctcgcg gggaccgccg atggcggaga tcgacagtgt
     3661 cgaagtcatt tctgatccgg ggccctttcc cgacacgttc ctgatcgcgg agagcgacag
     3721 gggttcgctc tcgggcatga ttcccccgga tatcgccacg tgcgccgagt gcatccggga
     3781 tatcggcact ccgggcgggc ggtacgcggg ttactgggca acgtcctgcg tcaactgcgg
     3841 tccccggtac agcatcatcc gggacctgcc ctacgacagg gagaggacgt cgatggccgc
     3901 gttcccgccc tgcccggcat gcgcagggga atacggcgac ccttccagca ggaggcacca
     3961 tgcccagacg attgcgtgtg ccgcctgcgg tccggcattg cgcctcctcg acgcgtccgg
     4021 aaaggaagtg ccctctcctg acgtcatacg cgaaactgcc cggctcctcg atgcagggtc
     4081 tatcgttgcc atccggggaa tcggcggttt ccacctcgcc tgcaccgagg aactcgccgg
     4141 tgagctgaag cggcggctcg gtcgccagga acagcctttt gccgtcatgg tcaggccgga
     4201 ccacgtggaa cggatcgctt tcgtctcccc ggaagagatg gctgcactgc agggccacga
     4261 aaggccgatt gtcgttttgg aaaagcggga cccggaagcc cacgccacga tctcgaacct
     4321 ccacaccatc gggtgcatgt tcccgtatac gggcctccac cacctcctct tctcccacct
     4381 tgcccatccg ctcctgatca tgacgagtgc caaccttccc ggctacccca tgatcacgga
     4441 gatcgacgtc gcgatggcga agttgcacga catggccgat ttcttcctca cccacaaccg
     4501 ggcgatcgtg aaccggtgcg acgattccgt cgtcagggac gggttcatca tccggctctc
     4561 ccgcgggctt gcgccgaaga gaacacggat tgatcttggg gatgcatcca tccttgccgt
     4621 cgggccggaa ctgaacgcga acgtgaccgt ttaccgccag ggtttctgca cgacctctcc
     4681 ccacgtcggc aacgtgcgca atccccagac ctatgcctac ctccaggaga cgatcgccac
     4741 actctgccgg ttcctcgggg aagggttcga ggtcattgcc cacgacgccc atccccagtt
     4801 cctgtccacc cggtatgcaa gggaactatc ccaccgctgg gatgcgaccc tcgtccccgt
     4861 ccagcaccac caggcccata tcgctgcgac gacccgggaa gagtgcatcg ggatagcgat
     4921 agacggtgtc gggtacggca cggatggtac ggtctggggc ggggaagtct ttgcagggtc
     4981 ccctgccggg tacgagcgtg tcgggcacct cgaggtcgtt cccatgcccg gcggcgacct
     5041 cgcgacgcgt tttcccgaaa ggatgctcta cgggattctc cccgtgccgg aggtgacggc
     5101 cctccttgcc gcgaggggct ggacagacgt cgagatcacg ttcctcgaga cgcagcttga
     5161 ccggaacctc aacgtggtcc ccacgtccag cacgggcagg gtcctcgacg cggtgtctgc
     5221 actgctgggc gtctgccggg agaggacata cgatggtgaa ccggcgatga aactcgagtc
     5281 ttttgccacc ggcgggaagg cggtcccctg ggacctcgta tacagaagcg acgggggtcg
     5341 ggaagtgctc tccacacgtg ccctcgtgaa aagggcgctt tcggaagccg gaaaagcggg
     5401 ggaccgggct gggctccggt ccgttgcagc atcattccag ttcaatctcg cacgcgggat
     5461 cgccgggctt gccatccatg ccgcacagga aaggggtgtt cccctcgttg ccctctcggg
     5521 aggcgtcgct tacaacaggt ccatccgcga gaccatccgg gccgaggtga cgaaggcagg
     5581 gcttgcattc cacatgaacc gcgggtaccc cctcggggac gggtgcatat cctatggcca
     5641 gtgcatcgtt gccgggacac tcgaacggga agggtcgtga gcgggcgcgg ttcttcactg
     5701 taagtaccgg ggcaggggtc tggcataata ccccggggta ggtgccgtgc caggcaaaaa
     5761 aagggtcgaa aggttcccgg gacagccccc cttttgtcat tcccctccct gccgcagatg
     5821 gactccggtg aggacacaac gcgaacccca gctttcgatt tcgaaaaact cctgatttac
     5881 aggagtgtgc cggttcgttg tcccggcatc aacaatacag ataaaaaaaa agaatatatc
     5941 ccgctctatc agaaaccgga ccttgtcgga ctgagcacga tgaggggcac ttgtatcgtc
     6001 tttcctgcct gtacggtcac cgttttcacg gtcgtcttgt agttctgttt ggctaccttc
     6061 agttcgtggt ttccggcagg tatatcggag atcgtggccg ggctgatacc ttttaccacg
     6121 tcatcgatgt agatggttgc tccccgcgga acagtactga tcttgagtgc ccccgtccct
     6181 gtgctccctg tgacggttgc cgtgggagtc agcgtcgctg tcgggactgc cgttgggata
     6241 ttcgtggtca cggatgtcgt cgggatggtc gtcgggaaca tcgtcggtat ccccttcatg
     6301 aaaataatca gcgggacccg cttgtgttcg ccggggctga ccgtcaccgt cgttgtgtat
     6361 tccctgtacc ccggataggc agccgtgagg gtgtgcgtcc ccggttcaac cgcgtaatcc
     6421 tggagcggcg ttgtccctat aacagtcccg tcgagggcaa ccgacccccc gagcgggtag
     6481 gagaagaccg tgatgtatcc gggttcctgc ccgggttgtg tcggggttgc agtcggggtc
     6541 gccgtgggtg ttactgtcgc tgttggtgtt gccgtcgggg tcgccgtcgg ggtcgcnnnn
     6601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnccgt gggtgttact gtcgctgttg
     6721 gtgttgccgt cggggtcgcc gtcggggtcg ccgtgagtgt tactgtcgct gtcggtgttg
     6781 ccgtcggagt tatcgtcggg gttgccgtcg gggtcgccgt gggtgttact gtcgctgtcg
     6841 gaacgacgcc tccgacagag atggtgcccg ggatgactgt cggattgatc gggtcgccag
     6901 ctccgtcagg gtccatctgc ctcacagtga gaccgagggt tgtcgctccc gcgatcttcc
     6961 ccttcaccgt cagggtcacg agagtgacgc ccgtggcccc cggtgaaacg ccgagggaga
     7021 gatcacttgc ccgcaaggag acttccgatg caggcacagc cgagttcagc ttcatcgacg
     7081 cccatgacgg gaatgtaacc gccgttatct ctgcaacgga cgggtctgca actgatgcag
     7141 tcatgatgta acccgagagc cctgtcggga ggctgtcggc cacgattgtc acatcgacac
     7201 tcgagcctgc gtcaggtatc gtggcgggac tgactgtgac ggtcgttgcc agtgccggaa
     7261 cagcgagcag gcagatgcat gcgcacagga tgaccgtttc tttccacttg gtgaaataca
     7321 tgtgaatccc cctccttaca ccatcgtaaa gaggatgtag aggtcgtcga agtcgatacg
     7381 accgttgttg ttgtagtcaa acaggctcac gggctcgttc tcctggatcc actcgaggta
     7441 gaggaagtac tggaccacgt catcgaagtc tatccttccg ttcccgttga catcccagta
     7501 taccccgtca tggaacgggt cggttggcgg gttcgtatag cctggcaggg ggaggaggac
     7561 aacgacctgg acgggtgcct tgttgaccca cgtatagacc gggtcccccg tgtcggtatc
     7621 gatctgcgag acggtgacgt cgagggtggt tgtcatcggt gtttttcccg tgctgttgaa
     7681 gagcgcgagc tcgacgttcg ttgcaccggg cctgatgacg tcatcgatgt ctgacgcctt
     7741 tatccagacc gacggcgccg ggaccgtgct ggtgataacg aaactctcgt tcagccacga
     7801 gggtggacgg aacgtcacca tgtctgccgc ggaggcattc gtgaagaaga tcgtgatgtt
     7861 gtacccggaa agccccctct ccgcgtactc gaggacgagt ttcattgccg tcgtggaatt
     7921 ggtcggaatg atcgcagagg acgggacgaa cgtcaggttc actgtcgttg catttcctgc
     7981 gacggatatg tacctgctgc gggtcatcgt gttcgttccg aactcgtttc cggccgtcag
     8041 ggagactgtg tagttaccgg cgtggaggta cgtgtggttg aacgtgaggt tgttcgtcct
     8101 gttctcagtc tgaccgtcgc caaatgtcca caaccaccag gccgggtatc ccgtggagaa
     8161 gtcggtgaag gtaacattga ggggctcgac gccgatcacg ggatcagccg tgaaattcgc
     8221 caccgggatc tcgccgaccc ggatgtactc gaaccgggac atcgtgtcgt tgccgtagag
     8281 gttcctcacc gtgaggttga ccgtgtagtt ccccatcgcc gtgaacacgt ggacggggtt
     8341 cttggcagtt ccgttgggcg acccgtcacc aaacgtccag ttccaggagg ttactgcagg
     8401 aatggcggtc gagaggtcag tgaactgcac ggcaaggggt gccagaccga acgtgacatt
     8461 ggcagtgaaa ttggcggtgg gaacgtcccc tgcctcgacg atgccaaact tcgtgatact
     8521 cttactgccg taatcatttg ttgcggtcag tctgacatcg tagagcccgg gggtatggta
     8581 cgtccagttg gtatgctggt ccgtgctgaa gttcccgtca ccgaaactcc agttccaagc
     8641 gatcggtgca tcgttcgtaa ggtccgtgaa gttcacgtcg aagggaacct gtccctggca
     8701 gaatgtgcac tccactcccg agacgtttgc agagaaattc acgatgagcg ggtctccgac
     8761 ctggatgtat tcgtattttc cggtcgagtt gctcccgtcg aggttgctca ccgtcaggtt
     8821 gaccgtccag ttaccggtat agtagatatg gctggggtgc tggagggtcg acgtgttgcc
     8881 atcgccaaag agccatgacc aggccgtcgg ttcaccggtc gagagatcgg taaagttgac
     8941 gagcagcggg ggcaggcccc tgatgagggt atagttttcc acgccgttgg cttccgccgt
     9001 gaagtttgct accggcggaa cggaggcaat ccgggcgacg aatgcgtcgc taatccctgc
     9061 aagtgtcggc tggacggcat tctttaccgg gaagtttgct gactccgtat atccgacgat
     9121 cgttacattg gagtctaaga gtgctattcc catggccctg tcatcgagcc ggccacccag
     9181 gtacgtcgag tacatgagcg ctgtcccgtt cgggtagaac cgggtcacaa atgcgtcgta
     9241 cgtgtaggaa ttaagggctg actggacggc attcttcacc gggaaatcga gcgaatccgt
     9301 gtagccggtc acgaatattg atcccatgtt atcgacagca acccccctgc cgtcctcgac
     9361 cagctgtccg cccaggtacg tggaaaagtt caccgtgcgc ccttccgggt tcagttttgt
     9421 caggaacgcg tcctggagac ctttcagctg taactgatag tgcggtgggg gggaggttat
     9481 cttgatgaaa tccattgacc gtgtgaaccc cgtcacgtac attgccccgg tattgtccac
     9541 ggcaatacca ttcccggatt cctcgtcagt gccccccagg tacgtggaag atataatgga
     9601 gcctgccgtg ggattaaaat gtgtcacgaa ggcatcctgg cctccggaaa gcgagctacg
     9661 gtacgcgttt agggtgggga aatccgaaga tttcgtcaac ccggttacga aaatgtcccc
     9721 gtttgcgccc aatgcgattc cattggccct gtcgatgttc ccaccgccga ggtatgtcga
     9781 atttgcgatg gatgaagctg atccatcata ggatattcct gtaacgaatg cgtcccaagt
     9841 accgttcaat gttgtatcat acgctcccgt tgtcgtcggg aagttgtccg atgccgtgga
     9901 accggcaatg accgccaccc ctgaactggt gagcgcaatg gcctggccga tatcggtcat
     9961 gttcccgccc aggtacgagg agaactcgag gtcgtacccc tcgggtgtca ggacggtgat
    10021 aaacgcatcc gcagaggaac aacaggtccc gctgtaactg atattctcct ggaaggcttt
    10081 gaggacgggg aaatcaggcg agatcgtctc tcccgtgaca aacgcgtaac ccgagtcgtt
    10141 cacggcaatt ccgtgcccga tatcgtcata atacccccca aggtacgtcg agtagttcat
    10201 ggaaagacca tcgggctcga acttggtgac aaacgcgtcc agcccgccac cgggatcttc
    10261 ctggtactgt gccttccagg acggatacgg gaagtcgatt gactgcgtgc tccccgtcac
    10321 atatgttcct cccagggaat cgacggctac ggcatacccc cggtcatcca tgctcccccc
    10381 gaggtacgtg gaaaaatcaa ggtaggggtc aatgacgagc gggagggcag ggtcgtacgc
    10441 accggtgtca aaaccgacga gcccgttgcc ggagaggacg tacctgcagg agaccggcac
    10501 cctttctccg ttccgctcct ggtaacagac cggggctgcc tccctgatcg tgcctgccga
    10561 cgtcttcacg aggaggtttc cgtcggtatc gagggcaagg tcatcctggc ctgaataccg
    10621 gaagaggaga gccgagggat cggctcccgg ggaaaggacg atatcgcgct tgaggactcc
    10681 ctgcgttccg gaatagacga tatcgactcc cgggaggata ttgctgtacc gcacccttcc
    10741 aaacgtcggg acgtcccgta cccatttgga gggatcgttc ccgatgaaga agtttgcttt
    10801 tcctccgagc ttgtcttcac ctgttaccac cacgccgggg gaatgcccct cgagcgcgat
    10861 ttcgactgat gccggggaaa tgcccccgct tcccacggtg aataccactg catccttcgt
    10921 gaagaagatg ctgtgtgctg gtgcattcgc gtggtagagc acgtcatcgc tcacctgtcc
    10981 ttcgttctgg atgaaaacga ggggcagccc ggatacatcc actgacaggg acgtcccggc
    11041 tgttgccggt gatactgcca gtgcaaggag aacaatgacg gcaacaaata gcactgtgtt
    11101 tctttgactc gaactcatga atttcgcctc cagtcatgac cggcatggca gaccccgtgg
    11161 ggaggtgcat tcccgccacc ttgagaggaa cacgacccag aacccaggga atcccaggcc
    11221 agggaaaggg gtggtttctg atcagattcc tttataaaaa accctctctt ctccatgctt
    11281 ataaatattt ccctgaatgt gccagaaatt ttctcctttt tccataacag aaacaaaaaa
    11341 catgcatcca tcgatcaggg acctgtacct gagttgtttc ggttcatttc acactccttt
    11401 gccccacaag gggcttttca tggcatggat tcaaacatca cgggttaacc accgtgactc
    11461 agggttcacc tgcgacacct tcccggagcg cagaagtccc cggattggag tcatggttcc
    11521 ccaaaaagag gagaaatcga aggtcttttc cctttccgcc aaaaaattta tcttgagcct
    11581 gtgcagacaa ctagaagcaa taccatcagg aaggtgaatt cacatgttgc ttgcaaatgc
    11641 tgtcgtcggt attattcagc tggtaattgc catcatcctg gcagttatcg cgctctacat
    11701 cggattttcc gtgctctcac ggatcacgaa gggtatcgag gaggagaagg aacttgcaaa
    11761 aggtaacgct gcggttggaa tcatcgtcgc ggctgtcttc tttgccattg cactcgtcgt
    11821 ccagtcgggg gtatcaggga tatcgctcgg agtctcaaag gccctctctg tcggtctctt
    11881 ctcgatggac gggatcgtcg caatcggcgt ggcgatactc cagctcatcc tcggcatcgt
    11941 ccttgcggtg ggtgccattt acctcgcact ctcgatcctc gacaggctga ccaagggtgt
    12001 ctcggagttc gaggagatca ggaagggcaa cgtggcagtc gccctggaga tggcgggagt
    12061 catcgttgcc accgctgtca tcatccagtc cggggtcatc ggggtcacct cggctctcct
    12121 ttgagtcatc ccgaagagag accccctttt ttcccttttt catcggcccg gtgaaataac
    12181 cacccgggga catcgtggaa ctataccagg agggctcttt gttcttttgg tgggtagaag
    12241 aactgcaagg gggaatgaac atccccgtac tctcacgtga gaactgcccc ggcggctttt
    12301 tcaacaatca attaaaaacc agatatttct tatttggatc aaccaatccg gaattgcgag
    12361 tgggtaaaga accctcgtgc tgtttaccac ctgaaacgac aaagaaagtg gaagaaaaga
    12421 gatgagatat tggccaaccg tttcatgcat cggtttcgtc ctttttcccg gccccgggtt
    12481 ccggtttcat ctggggaaag aggatgacct cctttatcga ggggcggttg gagagcagca
    12541 tcaccaggcg gtcgatccca atcccgacac cccctgtcgg gggcatcccg tagcccagtg
    12601 cgttgatgaa gtcatagtcc agcatctggg cctcgaggtc cccggctttc ctcttctcct
    12661 cctggcgctg gaaccggccg agctggtcga ccgggtcgtt cagttctgaa aagccgtttg
    12721 caagttccat gcccgcaacg aagagctcga acctctcggt gaagccctcc cgcgacctgt
    12781 gccgctttgc gaggggcgag ttctcgacgg gaaaatcgtg gatgaacgtc ggctggatga
    12841 gctgttcctc gacgagtccc tcgaagagga cgacgagcat ttcccggtgg ttttgcgcgt
    12901 tctcccactc ctcgataccc cggtcccgtg cgatcgcctg gagttcttcg agggtgtggc
    12961 tccatatgtc gatcccggca agctcccgaa ctgccccgtc catcgtcatc ctccggaacg
    13021 gcggggtaaa atcgaggctg gtctccccga aggcaacgag cgtctttcca tggatttcct
    13081 gcgtaatcgt cgagatgatc ccctcgcaga gtgccatcat gtcggtgtag tcacggtacg
    13141 cctcgtagat ctccaccatg gtgaattcgg ggttgtgctg ggtatcgatg tcctcgttcc
    13201 ggaagttccg cgagatctcg tagaccttct cgaatccccc gacaacgagc ctctttaagt
    13261 acagttccgg ggcaatccgg aggaaaagcg tctgctggag gtaatggtgg aacgtcgtga
    13321 agggccgggc atttgcaccg ccgtacacgg gctggaggat gggggtttcg aactcgagga
    13381 acccgcggtc accgaggaat ttccggaggg ctgcaacgat cctgctcctg gtccggaagg
    13441 tctcgcgcac gtccgggttc acgatgaggt cgacatacct ctgccggtac ctcttctcga
    13501 cgtcacgcag gccatggaac ttctcgggaa gagagcagag tgccttggaa aggatggtga
    13561 tatcctcgac ccagagcgtg agttctccaa ccttcgtccg gaacgcatat ccctgcaccc
    13621 cgacgatgtc ccccctctca aagcacgtct cgaagagggt gaacttctcc tccccgagat
    13681 cattcttccg gatgtacagc tggatcctcc cgctctcgtc ctggagatcg gaaaagattg
    13741 tcttgccgtg gttcctgacc gtataaagcc tgccggcgac ccggaagagt tccgttccct
    13801 tctcatgtcc tgcacctgct gaccgttccc ggaccgcggc aatcgtctcc ctccccggaa
    13861 aaacataggg gtagggttcg atcccccttg ccctcagctc ttttaccttc tcctgccgcg
    13921 attcttcgaa tgcaaggtca ctgttctcca tcagcctctc cgtcacacca ccgtggcgct
    13981 cttccgcacg atggagagat ggtttccgcc atctctcctc cgcccttttt tcggggtaat
    14041 ggaccgcacc cctgccacgg gtttttccag agaattggcg ggataaggtt ataatggtat
    14101 attgcctgca ggggaacagg acaaaagcga tctctttttt gtgttcgcgg ggcacccggt
    14161 gacccccata cctaaataaa aagcgcacgc acactttccc ggagagatag atatgaaagt
    14221 catactgctc tgcgggagcc cgcgaccggg gggaaacaca tcccagatcg tcgaggaatg
    14281 tgcccgggtt atccaggaga aagggcttga gacggaggta ttctcgcttg cagggaagaa
    14341 gatcgagtcc tgcacggcgt gcaaccggtg cgcaacagaa ggcaactgcg ttcttgagga
    14401 tggcctcgcc gatatcatcg acgccatccg gggagccgaa ggatttatcg tggcatcccc
    14461 tgtctacttc gggactgcca ggggagacgt catggcagcc ctccagagga taggtatggt
    14521 atcacgctcg accgaccgtt tcctttcctg gaaagtcggg ggaccgatcg cggtcgccag
    14581 gagagggggc catactgcga ccatccagga gatgctcatg ttcttcttga tcaacaacat
    14641 gatcgtgccc ggttccacgt actggaacat cgtctttggc agggaccccg gcgagtgctg
    14701 gaaagacgtg gaggggatga ccaccgtgcg tgtctttgcc gagaacgtgg cacgcctgat
    14761 tacaaagatc tcgggatgaa actaccggag agttccgcga caccatggaa agccctccca
    14821 tcatcgaagt ctcctcgctc ttccattcct acggtgagac agaggccgtc aggggagtct
    14881 cgttctcggt ccgggaggga gagatcttct cgctcctcgg cccgaacggt gcggggaaga
    14941 gtactgtcat caacgtgctg atcacccttc tcccgctcca gaagggcacc gtcacgatcg
    15001 cgggatacga cctcgcccgc gatccggcgc acgtccgcag gtcaatcggg atagtcttcc
    15061 aggaggtcac gctcgaccgc gacatgacct gcagggagat cctcgagttt cacggcaggc
    15121 tctaccagat gccgggggcg gaacggaagg cacggataga ggaacttctc gcgctcgttg
    15181 aactcgaggg aaaagccgac accctcaccc ggcacctttc gggcgggatg aagcgccgcc
    15241 tggagatagc ccgggggctc atgacccgtc cccgcatcct tttcctggac gagccgacaa
    15301 tcggcctcga cccgcagacc cggcggagga tgtgggacta tatcagggct gtcaacggcg
    15361 aggggacgac gatattctta acaacccact acatggacga ggccgacagc ttgagcgacc
    15421 gtatcagtat catggaccat ggcacgatcg ttacgaccgg cacggggtgg gaactcaaga
    15481 acaggctcgg tgaggatgtc atttacttgg aaacaagcga taacacccgg gcccgcgatg
    15541 tgctcctcgg cgtgccggat gtcggggacc ttggggagaa gtcccacgga ctccttgcaa
    15601 cggtcaggaa agacgggacg ttccttttgc ccgtcctgat cgagaggctc aattcggaag
    15661 gcatcagggt caatgccgtg aatctcaaga aaccatcgct tgacgatgtc ttcgtccact
    15721 ataccgggcg ggaactccgc gacgagggac ggggacagga gacccagcac gcaggcacag
    15781 caggggggag gtcaaaatga ggcagtggac aggctttctc acgatatact ggcgcgacat
    15841 gctccggttc ttccggttca agaccctcct cttctcctcg cttgtccagc cggcactctg
    15901 gcttgccttc tttggcatcg cgatgtcggc aaactttgcc aggctctcgt ccgggatggc
    15961 ccccctcccc ggtatccggg aggtcgggta cctgacattc atggctgcag gggtcatcgc
    16021 tttgacgacg ctctttacga gcctctttgc gggtatcgtg atcctctttg acaagaactg
    16081 gggcctgatg cgtgaggtga tggcaagccc ccttccccgg gaacacgtca tcgtggggat
    16141 cggtctctca ggaatgacca agtcgttcat ccaggtctct atcataacgg tctttggcat
    16201 cctcatcggc gtggagttct tctccggtta cacggcggtc cggatcctcg cctccctgct
    16261 gggcatgttc ctcttcgtcg ggatattctc gcttgggttc gtcttcctct cctctgcaat
    16321 cgccgcgtcc ctggagagcc ccgaggggct ccagggaatc atgacactcc tctccctccc
    16381 gctcttcttc gtgagcaatg cactctaccc tgcagcggct tttcccccgg ccctcaatgc
    16441 cctctcggct gcaaaccccc tgacgcacct gatcaacggg gtacggtatt tcaccatcgg
    16501 gccggacttc caggtcatcg gtgtccacta cgcggtaacg gtgcaggaca tggtgctctc
    16561 cttcggagtg ctcgttgcct ttgcagccgc catgttcgga atcgcgctct ggagatttgg
    16621 aaaggccgtc gtgacctgaa acagcccggg atccttgtat ccccgtcgtt ccgccgggtc
    16681 ccggaccacg gggcagcgtc aggacccggg gccggccggt tcgccggggg cctggacccg
    16741 gtacagaggg agacttccaa actcctctgc aaactcctgt acctgccagg tgtcagaggc
    16801 tgccatttcg tggaggaacg cggggggtaa tgctgcgccg aacttccatg ccgacgggtg
    16861 cggaacggga atggccgcct cgatcccgga aacggacatc tcctgtatct tccggaatgc
    16921 ttccagcacc cggtccgccg atccgggtcc tcccacgcgg ggaaagagga gggatatgtc
    16981 gtcgtaccgg accttcgtgc attcaccgag aaccgaccgg gcgagcagcg cgaggagggc
    17041 attcctgccg cgggacagga acgtgagcgc gacgacgtcg cgtttcttcc cctgcccggt
    17101 ctcccacacg tggattcccc gggaatgcag cggggggaac gatgcgatgc aggatgcgat
    17161 ctcttcctcc tcccgcggtc cgaggggaag gagcgtgcgc ccacgcccga ggatccgctg
    17221 caccgaacgg cagacttcgg gcgacagtcc tgcctgttga ccgcccgtcc agaaggcgcg
    17281 tcccccggtt tccccgccgg ggacgacaac gacgagcccg tgctggtcgt ccctcccgac
    17341 cagcgtccag tcccttccgc caagcgagaa cccctcccgg ccccttcctg caacgaacct
    17401 tgcatccagc ctcccgatct gttccccgtc cggcgtcacg gccctcacct cgccgccgcc
    17461 ctggatgacg gagtacaggt cctttccctg tgacctgccg tacagggatt ccatgcgggg
    17521 accgctcatc aggaactcgc cgtccctgac aaggaatccc tcccgttcga ggaacgcgat
    17581 gagttccctg actgcgccgg ccggaaggtc gcagaacccg ggaagggccc ctgtctcctt
    17641 ctcgatgcgg gccgcagtcg tccgccggtg ccggaggact gcaaggaaga cctgctggac
    17701 gaggacgtta tatggtttct ttttcggaat gagaggctcg accctctttt tgcgggcact
    17761 ctcgataacc gcggtgctca cgaggagtgc ccatgcgtca gggaggacga atgccatgta
    17821 gggtgacccg ccccgcctcc cgctccgccc catcctctgg aggaaggagg agaccgatgc
    17881 cggtgccccg acctggacga cgatgtcaag gtcaccgatg tcgatcccga gttcgagcgt
    17941 gctcgtgcag atgatgcacg cgctctcgct cccctcgagg gactcttcgg cagccctccg
    18001 catctggggc gagagggacg agtggtgcac gaagaggtgc cggacagtcc cccgcaatgc
    18061 gctgcccagc tcctctgcct ctgcccggct gttgacaaag acaagggctt tttttcccgc
    18121 aacgagaccc gccacgacct gcgtacgccg tttgggatcc gcctggacgc tgaaggagaa
    18181 cttcttttcc cggggaggct gcaggacttc cacgacttct cccccgcgtc ggggacccga
    18241 gaaccatgcg agcacctcgg ccgggtttcc caccgttgcc gagagcccta tcctctgcac
    18301 gggagacccg gccagcgcgt tcagcctgtc gaggaggata cggaggtgca ccccccgttc
    18361 agactccacg aacgagtgga gctcgtccac gatgacgaac cgcgtgcggg cgaggtcccg
    18421 cgccagggcc ttctctccca tcaggacctc gagggactcg ggcgtgatca tcaggacgtg
    18481 ggggggttcc ccgtcgtccc atgaccggtc tcccctgggc acgtccccgt gccagacctt
    18541 caggtcgagt cccgtcggga tgcagaaaga gaggaaccgc tcttcctggt cgttgatcag
    18601 ggccttgagc ggcgagatgt acaggcatgc gaccccggag cgtccctctt tgaggatcgc
    18661 atcgatgacc gggatgaggg ctgcctcggt ctttcctcct gccgtggggg cgatcgcgag
    18721 gacatccttt cctgtcctga ccgcccggta ggtccgggcc tggacttccc ggagatggga
    18781 ccatcccagc ctgtgggaga gcacgtcctg aagggcctcg tgcaggccga aaaagacctc
    18841 ggaatccatt cgctgatcca catgttctct ccctccccgg ttatcacttg tgctgttcca
    18901 aagaaaaacc cataaataca tggtcttatc cacgtaactt acagggatga cgacgacgct
    18961 ttcgacaagc tcttcacttt ccggcgccgg cgtattcttc ttcctgttta ggtaggggac
    19021 cggtccttct ttctggtccc ctgtaacggt atcatccctc gagtttaccg gaggtttctc
    19081 tcatgctcgg aattcctgac ccgcaaatct ggatcgcgta cctgctctgc atagccctcg
    19141 cgttcgcatg catcgtctac ggctacctca actggaacaa cgggggagat tgagggatgg
    19201 cggtcaacgt tctcctggtc gcaagcatca ccctcatcta cctggtcgtc attctctgcc
    19261 tcgggtacct gggttacaag aagacccgcg aggcagagga ctatctcgtt gccgggcgga
    19321 aagcccatcc ggttgtcatt gccctctcgt acggtgccac gttcatctcc acatctgcca
    19381 tcgtggggtt cggtggccag gctgcaaacc tcgggatggg cctgatctgg ctgacggtct
    19441 tcaatatcgg cgtgggcatc ctgctcgcct tcgttgtgtt cgggaaaaag acacgggagg
    19501 tcgggcagcg cctcagggca gtcacgtttc ccgacctgat gggcaagatc tactcgtcga
    19561 cgttcatgca ggtcgtctcc ggcctcgtca tcgtcgtggg gatgccgctt tattccgcgg
    19621 ccgtcctcat cgggggtgcc cagttcatca aggagacgct cgggatctcc tatgccgcgt
    19681 ccctgatcgg gtttgccgtg atcgtggcca tctatgttgt cttcggcgga ctcatcgccg
    19741 tgatgtacac ggacgcagtc cagggggcga tcatgctcgt cgggatgacg tttctcctta
    19801 tcctgaccta cgtcattctg gggggcgtga ctgccgccca ttccgcgctg accgcgatcg
    19861 cggacatggt tccccagaaa cttgccgagc aggggatgca cggctggacc gtcatgccgg
    19921 atttcggatc ccccatctgg tatactctcg tcacgaccct cgtcctcggt gtcgggatcg
    19981 gtgtcctcgc ccagccgcag ctcgtggtcc gcttcatgac ggcaaaggac aaccgttccc
    20041 tcaacagggc ggtcctcgtc ggggggccgt tcatcctcat gatgaccggt gtcgcgttca
    20101 cggtcggtgc actcaccaac gtctacttcg tcaatacgca ggggaagatc gcgattgcgg
    20161 ctgccggggg aaacgttgat gccgttattc ccctgttcat caaccttgcg acacccgaat
    20221 ggttcaccgt tgtcttcatg gtcaccctgc ttgccgcagc catgtcgacg ctgtcatcgc
    20281 tcttccatac catgggaacc gctctcatct gcgacctctg ggggaggggg agggagtgtg
    20341 ccctctccct gaaggcaaac caggccggtg tcatcgccat gatcgtcgcg agcgttgtca
    20401 tcgcattcct gatgccggga agcatcatcg ccatcgcgac cgccatgttc atggggctgt
    20461 gcgcctgtgc cttcctgccc gtctttgccg tggccgtcta ctgcaaaaat ccaagtcccc
    20521 ttgcggccaa ggccagcctc gtgaccgggg ccctggtctg gtttgcctgg gccctcttcg
    20581 tgaacgcccg gtattccgct gtgttcgggc tctcctccgc actcatcggg aaaacgagcg
    20641 tcctgccatt cccgtggagt gcaatggacc ccctcatcat cgggctgccg ctctctgccg
    20701 ctgtgatcct cgtcctccag tacctccacc gtccggaagg ggcaaaggca ggcctctcct
    20761 gattattttt ttcgcgtgaa ctgcctatct gcggttatca cacggttacc cgataatttt
    20821 aaccgggtgg tgaaaacggg gagggatggc tcttccgcac cattacctcc gcacatcgtc
    20881 gccccaccaa atcactggtg ccccggtccc accgactttt ccattttcca gcggtaaacg
    20941 aggtatgctg ccgcgagggt gccgatgatc cccaccgcaa gggaaatgcc gatagcagga
    21001 cttgcaacga tcatctccca gacaaatgcc gagccgagag cgatcaggta acagccaagg
    21061 aacgccccga tgacgatggc ccaaaagacg tcccaccgct gcatcccgag cagcctgccg
    21121 agcagggtgg ccccgacacc tcccgagccc tggaggggga acatcacgaa gaggacgacc
    21181 cccgtaaagc agaacctctg cagccatggg cggcgggaga ggtactcctg cccatggccc
    21241 atgaaacgtt ttatccaggt accgagcagg gggatacgga gggctgcatc gaagttcagg
    21301 gccatgaaca ggccggcgag gacatccagg agcgccattg acgtcccgac cagccaccac
    21361 gggagaccga gggcgatacc gagcgggatg accgtctcct ttcctgccgg cgggatcacg
    21421 tatgccagca tgagcgcccc gaggaggagt gcaggttccc tgggaaggaa caggaagcag
    21481 agcccataat aaatccctcc gaggaggaag ggcacggaaa ccctgaatac aaggtgatct
    21541 gttggaaaag gggagtgccc tgcgtgatcg tccattgacc tggtagtaca tcgtcttttg
    21601 ggatactaca taaatgcgtg tcccccggag ccgggggtga ctattggctg aagcgcaccg
    21661 gaccgcgtgg agaggtcttc taccgcggtt ccgccccgcg ggcccccgcc cgccggatct
    21721 cggcgtggag gaggacgagg gagagcgaga caagattcag cgtggtcgcc gcgtaccaga
    21781 accaggcctc cacgggggag aggagggcga tccaccctga ccagagcatc gcactgatga
    21841 tgaggaacgt caccagcgta tccagtgcca ggaacacgga cggtactccg aagaaggcgc
    21901 cgacctgggc tatggtgcag tactcgaacc gggcctccct ccggaccagg tcaaagaggg
    21961 ctctccctgc gttcatgatg aggtctgcaa gtgcccaggc cgcaatggcg agccctgtga
    22021 cgataagaaa tccattgggg agactcgctc cgacgcggaa cgctgttaat ccaaacagga
    22081 gcttgaacgt gcagaacggg atgccgatcg tgagggagag aaaaacgggt ctcgaaaata
    22141 gttctgccag gcgatcggag ttcccgccgg aatcatgccc gccctctccc ttctcctttt
    22201 gtccggtccg ggccattgcg cagttgcccc tccttctgtc ggctcccgcc cctgtcagcg
    22261 accgtccggg cccggtgctc cgtgcccggt tgcccgatcc ggcgtgcggg tattacgtcg
    22321 tctccccttc tctccatttc cggtagagct ggtgctcgat gccgaggatg tcaaagacct
    22381 tcccgacgac atggtccacg aggccctgga tattccgggg cctgtggtag aaccccgggc
    22441 atgcgggaag gatgactgcc cctgcctctg cgagcgtgag catgttgcgg aggtgtatgg
    22501 cagaaagcgg cgtctcgcgg ggaacgagga cgagcggacg acgttccttc agcgtgcagt
    22561 cggcggcacg caggaggagg ttgtcggaaa agccgcaggc tattcccgcc actgtcttca
    22621 tgctgcacgg gatgactacc atgccctggt gcctgatccc gcccgacgcg aggggagacg
    22681 tgaaatcgaa actgtcatgg accctcgttg cgagggcatt gacctggtcg ggttccaggg
    22741 acgtctctat cccaatcatc cgggcggcaa gatccgtcat gatgaggtct gtctcgaggc
    22801 cgagctcgcg ggcggcttcg aggaggcgga tcccgtaaac gatgccgctt gcacccgaga
    22861 gagcgacgat gatgcgggtt tttgccattc agatagagat gtgacggcca tggcataaat
    22921 agggttgcgt gggatggggg gcaacagcag ggaagaccgg gtgtttccac cctgaagtgg
    22981 ggtgatatcc ccgaaaaagg gcacatcacc cttatagccc gaacacccgg atgatgcgtg
    23041 cccgtatcgt ctctttgggg tatgccccga tgatcctgtc caggagtgct ccctcgcgga
    23101 agaggaggat ggtcgggata gcggagattc caaaccgcgc tgcgagccgg gggttatggt
    23161 ctgtattgca cttcccgaat gtgacgcggc cggccatttc caatgcgagt tcctcgataa
    23221 ccggggccac catgcggcac ggcccgcacc attccgccca gaaatcgatc acaagcctcg
    23281 ggtgaccggc aaggagagtg gaaaaccggg actcgtcgac cgtcaggacg cgggcaggct
    23341 gcggctgtcc tttccccttc tgctccagga gccgggcctc gagctcgcgg agcctctttt
    23401 ccctgatgcg ttgcagttcg tcgtcgtcca tgtatccttc ctatggtgca tcgtccagat
    23461 aatcacttct tccgtccgtc tcctgcctgc ccggctttca ttccggggca aactatatct
    23521 ctgcggatag tgaattaatt acccaccaca tacgtctcag cgaggtgggg tagtcaggat
    23581 atcccgacgg gctcataacc cgtagaccga tggttcaaat ccatccctcg ctatggagta
    23641 atcctgtttt tcgcgttttg gaacctggtg caaagccccg tgccgggttt gaccatttgc
    23701 ggcaggagaa gagatttttt aaaaaagccc tgcagtttgg gagactactc tttcccggtc
    23761 ccgaactttt caaggcgggt ctggtacgtc ccgtcgagga agtcaacggc gaccggagat
    23821 gagacctccc cggggatatc gacagggtat gtccccgtca ggcagcccat gcagaggttc
    23881 tccctcccga tcccgatgga ctcgacaagg gcgtcgattg tgacgtggtg cagggaagtg
    23941 gccgtgatgt gtctccggac ctcatcctcg tccctccggt gtgcgatcag ttcctcgcgg
    24001 gtgggcatgt cgacaccgag gtaacagggg gcaacgatcg ggggtgaccc gatccggacg
    24061 tgtatctcgc gggcacccgc atcgcgcatg atgccgatga tccggcggga tgttgtcccg
    24121 cgcacgatac tgtcatccac gagcacgaca gatccgttct cgaggtgctt gcggatgggg
    24181 ttgagcttga tccggacggc cctttccctc tcggtctggg tggacatgat gaacgtcctg
    24241 cccatgtacc ggttcttgag aaggctttcc atgaacggga tgcctgaacg ggccgagtac
    24301 cccactgcat atgctgtgcc cgaatccggg accgggcaga ccgaatccgc tggcaccggc
    24361 gcttcctcgt ggagttttgc gcctatcctc agcctgacgt catacacgag tgccccgtcg
    24421 agaacggcat ctgcccgggc gaagtagata tactcgaata tgcagtgggc cctgcgcgat
    24481 gcccgggcga tctgcatgct ccgcatcccc tccccgtcga tgcagatgag ctcgccggga
    24541 gcgacatccc gaaggaacgt cccgccgagt gcatcgatgg caacgctctc ggaggcaatg
    24601 atcagccctt ttggggtcct gccgaggcag agcggcttga tacccagggg atcgcggaac
    24661 ccgtagagca cgccatcgat catcatcacg acggaatagg agccgcggag tactctcatg
    24721 cacctgtgga ctgcgtcctc gatgcacccc gagttgctca tctcctcggt aatgaccttt
    24781 gcaatcagtt ccgtatcggt cgtggaacag aatatctggc cgcggcactc gtactcgtcc
    24841 cggagctggc ggccgttgac gaggttgccg ttgtgggcga tcgagatgac atggtcgcgg
    24901 aacgcgaagt tgaagggctg ggcgttttca ggccggtttg cgcccgtcgt cgggtaccgg
    24961 acatgaccta ttcccacatt cccatcgagg gactcgagga tggtggaatc aaagacctcg
    25021 gcaacgaggc cctggccctt gtgcttgaag agacgtgtcc cgtcgaacgt ggagatcccg
    25081 gcactctcct ggcccctgtg ctggagtgca tagagtgcat aataaatgga aaaagagacc
    25141 ccgccagcat ccctgatgcc aacgataccg cacatgatgg gtcgcttacg gagtcgggac
    25201 ctttggccgt ttcatcgtcc acttgtaact gcgcaatctc gaacttcttc caaagccaca
    25261 ggcagaacag gtcttgtgac gcacgtggta cgagatactc ccgcacctgc gacaggcaat
    25321 gtgcgtcttt ttctgccttt ttcccattga tggtgttcct ttcgacataa ctcaccttat
    25381 cttcttttta ttccagggaa ggggaaatgt agatcacgtt gtccccacgc acgatcaggg
    25441 tgccaacgct ccgcgactgt ccaccctcaa tctcctctgc cttgtccagc acgaggttca
    25501 tgtgcacatc ataaccctgc aggaccccgc gaagttccct tccgcccttg agggatacga
    25561 tgacaggctg ccggttcagc acctgatcca aaatatccaa cggccgtttg gtcataatcg
    25621 tacccgcgtt ctgtcagttt ggggtactat atgtgagcaa cccggataca taaatgtact
    25681 gcaggggaaa gggtatcgcc tgcggctttc ccttttgttc tcctcccgct gttccggtca
    25741 cggccatttt tccggctttt tcccgtgacg acggcttttt tgtatccggc agccataatt
    25801 ccagagggag caagagatgg ccaggatcac gccgaagaag cggcacaccc tgcggaagtc
    25861 gcaggcagaa gacctcaaaa acaggttgcg tgcagagatc ggggactcca cgagcctttt
    25921 cccatgggag ggtatagaga tcgtcgagac ggatggggag gtcaccctct tcctcgtcgg
    25981 gaaaaaaccc ctcgtcatgg agacgaaggg catcgtcttt cccactctcc gcgggctcct
    26041 cgagcacccg tttccggaac ggaagatcgt ggttgactcg ggcgcagtcc ctttcgttgc
    26101 aaagggtgca gacgtgatgc ggcccggcat cacgtcgatc tcacccgacg tccgggcagg
    26161 ccggcccgtc caggtggtgg aggaaaagta cggaaaaccc cttgcagtcg ggattgccct
    26221 cctcgatgct gccccgatgc aggagagaga gaccgggaag gtcgtcaaga ccatccactt
    26281 cgttggagac gagatctggg cgctcgaatt ctagggagca gacccccggt acccccgact
    26341 tccggggatc aggcaatccg ggcctctgga agggagatat cgccgattgc atagatacta
    26401 ttaaataaat aacaatagac aatttttcca tggtaaaatt cctggatacc ctgcttggaa
    26461 agagtactcc gtcgtcggaa gacgattata tggacctcga cctcgaagcc ctcgaagcgg
    26521 aagaggaggg ggcacccgcg ctttttgtca agattgcatc ggtcggggac atcaaggaca
    26581 gcccgcgtgt caaggacgaa gtttataacg ggaacatcgt gatcgttgat atcgcgaagc
    26641 tgaaagccga caaggtcatg tacgagcggg tcttaaaaga cttaaaagag gttgcaaagg
    26701 acgtcaacgg cgacatcatc ggcctcggtg accagcgcta cgtggtaatc acgcccaatt
    26761 ccgtgaagat ctcgcgggaa aagatcggcg gggtcagctg atctgtgcgc aaggtcgtac
    26821 ctggtccctg ccccgtctgc aacacagaga tcgagtacat ctaccagact gaagatattc
    26881 catacttttt tggactcctc atcatcagca cccgctgccc ctcctgcggt ttccggttcg
    26941 tcgatacgca gctcatggag catgccgagc cttcgcggtg ggagttctcc gtcgtgtccg
    27001 aggaagacct ctccgcacgc gtcgtcagga gcatgaacgg gaccatcacc attcccgagc
    27061 tcggggtgga gatagcgccc gggcctgcat gcgagggttt cgtctcgaac gtggaaggcg
    27121 tcctcgaccg cgtggagagg gtcgtcgaga gcgtcatcct ctgggcagag gacgaggatg
    27181 agcggggccg tgcccgcgcc ctccgcgaga agattgccag cgcacgggac ggtcgttttc
    27241 ccgtcacgct ggtcatcgag gacccgacgg gcaactctgc aatcctcgac gaccgggcac
    27301 tggtctatcc ccttaccgtg gaaccggacg gggaaaacga aggtcaggaa acctgacggg
    27361 gtcgggatag attccgtccc ggcccgtcac tggatggggg ttcccgcgag ccggacaccg
    27421 ggcgtttccg atacactgcc cacgaccctg ctcccctcca cgcgggagag gacagcatcc
    27481 acggaaggtc cgggcacgat gtaggcatag cccattccca tgttgaaggt ccggtacatc
    27541 tcgaccgtgc cgatttttcc cttctccctg atccatgtga aaatctcgtg ggggggcatg
    27601 ggatcggtga tatcgaaccc gtatcgcgag agccgcgtga agttgaggag gccccctccc
    27661 gtgatatggc acattccgtg gacctccgtt tcagaggcaa cgtcaagggc ttcccggtag
    27721 atacgcgtcg ggacaaggag ttcacgggcg atcgtccgcc ccgaggagag cctctcgtcc
    27781 caggcatcca ggctttcgac gatcctcctc gccagcgaga gcccgttgct gtgaatcccc
    27841 gaggaagcaa ccccgatgat gacgtctccc ggccggatct tcccgccgca gatcaccctc
    27901 tccttttcct ggatgccaag gcacgtgcct gcaaggtcga ggccgttgac gaggccctta
    27961 agggtcgccg tctcgcctcc gacaatgctc acgttcgcct gccgtgcccc ctcgtttaag
    28021 cccgcaccga tctgggccat ctgctcgacg gagagcgagt ctgccgcgat atagtccacg
    28081 aatgccaccg gctcgatgtt catgacgtag aggtcgttga cgttcatggc catgcagtcg
    28141 atcccgaccg ttgtccagtc gcggagccgg tctgcgacct tcatcttcgt cccgacaccg
    28201 tccacggtga gggcaaggac gtacctgccg cactcgacga aaccggcaaa atgcccgggc
    28261 ggggagacca tccggaacct tccctcgcgc cggaaagaga ggttccggac gagggcggag
    28321 atggcttctg cctcgaggtc gatgtcgacc cctgcctcgc ggtacgtcct cggtggaccg
    28381 ttacccattg tcctcctcgg agagccggaa ctcgtcatgc aggatccgga ctgcctttgg
    28441 cccgtccgcc ttggtcacaa cgaacgagat gttcagctcg gacgaaccct gagagatcat
    28501 catcacgttg acaccgccgt ttcccagcgc agaaaagatc cttcctcccg tccccctcgc
    28561 acctgccatg cctgccccca cgacggcgac ggcacagaca tcgctgttcg tggtcacctc
    28621 cctgacccgg ccttccgcga cgagcacgga gagtgcttcc tttgcggcat cctcctggct
    28681 ttcatcgatg acgagggaga tattggcctc cgacgagccc tgagagatca tcatcacgtt
    28741 gatgtcccgg tcggcaagga gcgtgaaaat tgccttggca accccgggtc tcccgatcat
    28801 ctgggccccg cagatgttga cgagggcaac cttctcgatg taggtgaggg ccttgacgac
    28861 gcggctgtcc ctcttctgac cgcggacgat ggctgttccc gggtgatcgg ggttgaacgt
    28921 gttcttcacc cggacgagga tgtctttttt catggcaggc tcgatggacc gggggtgcat
    28981 gacctttgcc ccgaaatacg agagttccat gacctcgtgg taggatatca ccgggatcac
    29041 ccgggcatcg ttgatgatgc gcgggtccga tgtcatgatg ccatcgacat ccgtccagat
    29101 cacgatctcg tccgcatcga ttgccgcccc gatcagcgct gcggagtagt cggaccccga
    29161 ccttccgaga gtcgtgacaa cgcccttctc cgtgcacccc atgaatccca tgatgacggg
    29221 tacggtgttc gttaagaggg gcagcacgcg gctctttatt ttcccctcgc ttgcagggat
    29281 ggcaacagcc tcgccgtggc tggctgtcgt cacgatgccg gcctcgcagc cgtcgagaat
    29341 catggacggg atacccctct gtttcagtgc ggcagaaacg acgaggctgt tgagcctctc
    29401 gccgaaagtg atgatatagt cgcgggagcg gggagtaagt tcccggaggt tgtgcaccgc
    29461 ggtgaggatg ttttccaggt tgcagagctg ctcctcgagg aggattccca cctcgtcggc
    29521 ataatcctcg gcagtctcga ggagaacctt cccgtgccgg acacgcaggg agttgatgaa
    29581 ccgtccgatc tcgtcggagt tatggttatt ggccagttcc gatgcaatgg cgatgagctg
    29641 gtcagtcact cccctctggg ccgagaccac gactgcgacc tcgttccctg cgcggtagca
    29701 ggactccacg atgtccacca cgcgggagac acttccgcca tctgcaacgg aagtgccgcc
    29761 aaatttcatc aaaaacctca tttgggctca cgctgtcctt tactatctct ttatgtacgt
    29821 atatgaccca cattataata agatgcggtc agccgaggtt ttggactgcc acgtccttgt
    29881 catcgggagt ggcggagcgg gagtcagggc tgctatcgag gcttcggggt atggggagac
    29941 catcctcgtc tccaagacgc tggcgggcaa gggcgggtgt accaccatgg cagagggggg
    30001 ctacaacgcc gtcctgaggg aggaggattc ctgcgggatt cactttgagg acacgatgaa
    30061 gggcggggcc tacctcaacg atcccgaact cgtcagtatc ctcgttgcgg aagccccgca
    30121 gaggatcaat gacctgcttg cgtggggtgc tgtctttgac gtgacagact cctgcgatgt
    30181 tgcccagagg ccgtttgggg gacagacatt tccccggacc tgctacgcgg gggacaggac
    30241 cggtcacgag atgatgatga ccctcatcga gcggctggcg tcgaccaacg tcgagataga
    30301 aaacgaggtg accgcccttg acctcgtgcg ggaaggagaa agagtggtcg gtgccctctg
    30361 cctcgacgga aagggtgagg tcatggtcat ccgtgcagac gcaacggtcc ttgcaaccgg
    30421 agggggcacg cagatttacg atatttccac gaattcctcg agcggaaccg gcgacgggtt
    30481 tgccatcggg taccgggccg gggccgagct gatcgacatg gagatggtcc agttccaccc
    30541 gacgggtgct gtctatcctt acgatgcccg gggccgcctc atcaccgagg ctgtcagggg
    30601 cgaggggggt atcctccgga atgccgcggg tgaacggttc atgtcccgtt acgatcccga
    30661 aaggatggag ctctccacgc gggatgtcgt ttcccgggcc attgcgaccg agatcctcga
    30721 ggggagggga acaccccacg gcggtgtgtt cctggacgtg acacacctgc caaggcagca
    30781 ggtagaggag aaactgcccg tcatgctcga gcagttcctc aagtttggcg tggatatccg
    30841 ggaagagccg atggaggtcg ccccgaccgc tcaccacgtc atggggggcc tccgcatcac
    30901 gccggatgcc gggacaacgg tcccgggcct ctttgcctgc ggcgaggtga cggggggcgt
    30961 ccacggcgca aaccggctgg gtggaaacgc ccttgccgat acccaggtct ttggaaaacg
    31021 tgccggtgag tctgccggca ggtctccaag gagggactcc cgcattgacc caaaggcaat
    31081 cgaggcacag gaagagcgtc tcgccgcctt cctcgatggg catgtgcctc cctcaacggt
    31141 gatccggtcg ctcaaaaccg cgatgtggga gggcgcggga atattcagga ctgaagccgg
    31201 cctgaataag acactcgggg tcatcagcca tctgtcctct ctccgcctcc ttgcccggac
    31261 aagagagaac cttgccgggt gctgcacggc gcagaacatg ctgctctctg cctccctcgt
    31321 tgtcaggggt gcaatcctgc gcaaggagag tcgcggtgca cacatgagaa aagacgtggt
    31381 ccagacatgg gatgcacgca attcacccta cgggcacacg taccagtcgc ttgaccggtc
    31441 cgggatagag acggcggtgc ggtcatgaag aagatacatg tccgtgtgtt caggtacgac
    31501 ccggagggag acgcccggcc ccattaccag aactacgtcg tggaggtcaa cgagggtgcc
    31561 cgcgtcctcc atgtcctcca ggccatccac gacgagatcg acccgaccct ctcgttccgc
    31621 tactgctgcg gggcaggcca gtgcggaagc tgtgcggtcc gcatcaacgg tgtcccggga
    31681 cttgcatgca tggaggaggc aagagacgac atgaccgtcg agcccctcga cctgccggtg
    31741 aaaaaggacc tcgtcgtcga cctcctgccg tacctcaaca ccctgccccg catccagccg
    31801 ggcggggagg catttgtccc tgacagggag aaggtcgagc tcatcaagcc gctccggagt
    31861 tgcatcgagt gcctctgctg cgtctcagtc tgccccgcca tggatgtcac ccggttcgac
    31921 ggtccggcag cgatgcgcca ggaacagcgg cttgcactcg acccgcgtga caggagagac
    31981 agggttacgg aggcagtctc ccgcgggctt ttcgcctgca catcgtgcca ggcctgctgg
    32041 aaggtctgcc cgaaagacat cgagataccg ggcaaggcga tcgagaaact gcgggccctt
    32101 gcaaacagga agggcctgac gctcccccgc caccaggaag ttgcacggct tatccgggag
    32161 agcgggagga gtatcgtccg gaccggcccg acgttcctcg aggacgctcc cgaggtcatc
    32221 gagcccgacg gcccggtcag ggcaaccgtc ggtttctttg tcggctgcat gtacaacggc
    32281 cgcctcccgg cgactgcccg tgacgcgatg gcagtcttaa aaaggaacgg tatccgtgtc
    32341 atcattccga gagagcaggt ctgctgcggg tcaccgctca tccggaccgg ccagatcgac
    32401 ttcatcgaca cgctcaagaa gcgaaacatc gatgcattcg tcttccggaa catcgatacc
    32461 gtcctcacca tgtgcgccgg ctgcggatcc accctcaaga acgactacag gacgcctttc
    32521 cgggtcatgg acatcaacga ggtgctcacg aagttcggga tagaagcccc tgcaaggctc
    32581 ccgatccggg tcacctacca tgacccgtgc cacctcctgc gcgggcaggg gatccgtgac
    32641 gagccccggg aactgatcac gcaggtggcc gacctcgtcg agatgccttc cgtctgctgc
    32701 ggttcgggcg gcggagtccg ctccgggatg cccgacgtcg cttccgcact cggcgagaac
    32761 cggagaaagg agatagaaaa aacgggggcg gagatcgtgg tgagttcctg cccgttctgc
    32821 gagttccatc tctcggagca caccgaccgc cctgtcagga atgtaacctc cctcctcctc
    32881 gaggggtacc gcgagaaaga ccggaagaag gcagaacaac aggtacaggg gtaatttttt
    32941 catttccgtt tcccacgggg aggcaggacg gggagaccgc ccctctggca ggatgtcatg
    33001 tacaccttcc tccttgctgc ttcccatacg gacaccaccg gcctttcacg ccatctcgat
    33061 gttgcggggc tcgagatcta cgctgatccc ctccttgaaa aggtcttttt cttcctgatc
    33121 gagaacgtgg tcaggtatgg agggggagca acagagatct cactctcatc gtgcgagtcg
    33181 ccggaggggc tgatcctctc tttcgaggac aacggttccg gtatcccgga tgaggagaaa
    33241 gctgcccttt tcgagacggt gatagggaag gagcggggct ttttgctctt ccttgcccgt
    33301 gagatacttt cgataactga tatctccctg cgcgagaccg gagaacacgg gaaggggaca
    33361 cggttcgaga ttgtcgttcc caggggaggt tacaggtttg ccgggcagaa tcctccgcaa
    33421 ttttcccggg acgcctgagg gcccaaaaaa aggcacgatg acgcaacccc tccctgacca
    33481 accccacatc ccaaccattt ttccgggaac cctgttcccc ggacggggat ggcctcaccc
    33541 acatttttaa tactccggtg cgtgagattg agttccatga caaacccctg gttaccctac
    33601 aaaatgcccc ctctccgggc atacatcctc gcccccggcg ttgtgcagat cgaagacatc
    33661 gtgtacaacc tgcctgcagg gacggtcgaa cgcggacgcc ccaggcctga caacccggag
    33721 ttcatcgtcc cggtgaagga gaactccgaa agtgcggccc gtgccgcgat ggaaggtctc
    33781 tatcggatcg tctttgatta aaaaacagta cctccccccc cggacgaaat ccgcatcgtg
    33841 tttttttaac catgatgccc ggccgcacgg cggtcacggg cggttaccgg gaaaatgacc
    33901 cctccttttt tcagacccgt gattcgacgg taaaaatgtt gtttttcctg gcgggaaatc
    33961 aggccgggcc gggcctgctg tccacaagaa actgatcaag cgtcgtctgg cgggaccgca
    34021 gcatctctgc gaggagagtg ctttccgcga taaaccgttc gggagagagg gtcatccggc
    34081 ccgcgacgtc tgcaagggca cctgcaaggt cttcgaattc acggtacggc tgctgcatgg
    34141 cctgccggac attctcccgc acgttgaaga cgccgagagg gatgtatccc gcccccgcct
    34201 cccgcaggac gatcgctccc gcctggagac cctcccttgc aagggcctcg agaaccgcca
    34261 tcttgcacga gtagtagcag ccaccgacgc tcgaatactc ccgttttccc cccggcccct
    34321 cgtggtccga gaagatgacc tcttcgttcc ccctgacccg caggaacgcc tccatccatt
    34381 cgtactccca cgggacgggg agaaggatga ctgcatagtg gttattgagg ctcgagaact
    34441 cgtggaccct gaccgtgtcg atgatgctgt tttgcctgac ctgccggaga tagaagtcag
    34501 cgagcaccgt gtcgcatgcc gtgatcgacc accgcgtcgg gacaagcctc ctcctctttc
    34561 cctggccgag ggcacccgtg gagagggcct tttggatccg ggagaagggg acacctttcc
    34621 ggtggaggtc gatgatcgca tcggctgcac agaggtcgcg gtcataatag cagcgttcca
    34681 ggtgcggatc gaagcgcccg ctgtccgcac ggaagttctc gaggggtgcg ctcgggccgt
    34741 agggagtaaa ttcctccgac agggagacac ctgtcggggc atggagaaac gagacctcgc
    34801 tctcgaggga cgaggaggag aggacaacct cctggagccg gagagcgaac ggatcctcga
    34861 cccggaagac gtcgtgggca cgcttgcccc ggacgaggtc gaggcggcag gcgaggatct
    34921 gctcctgcgt ccaccccgac gggatccagg actcgggggt gtccatgatc ccgcactcct
    34981 cccggacggg tgcaacgagc ggcccggcaa agacccgggg gtaattccag ctccccacga
    35041 agaccgaggg cggcgtcgcc ccttcgaggg tctttccaac ggggcgggac gttcccatcg
    35101 cgggccttgt gatcgatttg aggtacgcgg cttttccaag cgccatcctg acctgtactt
    35161 gccgggcagc aagataaacc tggaggatgc ggggagaaag tgcacccctt acatgcccac
    35221 gagggagagg aagaggcagg cggcaggcgg tatgaggagg ttgtcatcga gggggacggc
    35281 aagctccact gcacccgcaa cgagggagac gagggtcgcc cggaccgggt cgaggaatgc
    35341 acagaggaca agagagtttg cagccactcc cgcgaggaac ccctcgagag tctttctccc
    35401 gttcaccctt gtttttccga accggagtcc tgcaagggcc gataccgaat cgaggacggc
    35461 gagggacagc acacctgctg ctgccatggc ggagggaaag aaggcgacgc agaagagcga
    35521 actgacgacg aaatagatgg caccctttcc cggaaactct ccctcccgtt ccagccgggc
    35581 aacgaggaac gagatgagcg ggacgcggtg accggtcttt acgagctctg cgaggatgag
    35641 gccgggcagg agcgagcccg caagcagcag gatggcctgc tcacgcggga aaacgaagac
    35701 tgctcccgcg atggctgcac caaagcagag gtggacgagt tttcgggcct cttccttcat
    35761 tggatatgag atggttgttt ggatgccata acaggaatgg ctggaaagga gggggtggca
    35821 aagaatcgtg atcttttagt ggtggaatgc cccataccca ctggaatgac cgtgctggac
    35881 actccggcag gagagatact gcaggagaat gcgaccaccg tcgaacacct tgatatccgc
    35941 gggacccggg ttgaaaggat ccatggtgag ttctggacat cggggcagag gcaggcctcc
    36001 tcgatccacg agatctccta cagggggtgt ttcaagccgc agctcccggc attcttcatc
    36061 gagaggttca cgcgggaagg cgacctcgtg tacgacccct tcagcgggag ggggacgaca
    36121 gtgatcgagg ccgggctccg ggggagacgc gttgctgcaa acgacatcaa tcccctctcc
    36181 tgcatcctca cccgcccccg gttcttcccg cccgacctgc ccggggtcgc tgcacggctc
    36241 agcgggatac cctgccggga ctgcaggcag gatactgctc ctgacctctc catgttctac
    36301 cacgaaaaaa cagaggctga aatcgtctcc ctgcgggact acctcctctc gcgggaaagg
    36361 gaagggtcac tcgattacct cgacgagtgg atcaggatgg ttgcaaccaa caggctgacc
    36421 ggacactccg ccggcttctt ctcggtgtat accctgccgc caaaccaggc cgtctctccc
    36481 gaacggcagg caaagataaa cagggaacgc ggcctcgtcc cggaatacag ggatacaaaa
    36541 gccctcattc tcaaaaaaac gcggtcgctg ctccggaccg tcacaccggg agagagggag
    36601 cgcctgcgtg ctgccgggga gagcggtctc ttcctttcgt gtgacgcgcg caatactccc
    36661 cgcatccccg actgttccgt gcaactcacc gtcacgtcgc cgccttttct tgacgttgtc
    36721 cagtattcga aggacaactg gctccggtgc tggttctgcg ggatcgacac ggaggcaaca
    36781 gagaggctga tgactgttac ccggtcactc accgagtgga aacgggtcat gcaacagacg
    36841 tttttggagc tcttccgcat cacccgggag ggcggttacg ttgcattcga ggtgggggag
    36901 atccggagag gaacgttgtg cctcgacgag gtcgtcgttc ccctcggcgt gcgggccggc
    36961 ttttcctgcg agggcatcct cgtcaatacc cagcacttca ccaagacgtc ccacatctgg
    37021 ggcgtggata acaactcttc cgggacgaac acgaacagga tcgtggtgtt ccggaaaggg
    37081 agtgaggggt aaag
//
LOCUS       DAOOJU010000016        36679 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1252_length_36679_cov_16.453637, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000016 DAOOJU010000000
VERSION     DAOOJU010000016.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 36679)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 36679)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36679
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1252_length_36679_cov_16.453637"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(2..505)
                     /locus_tag="PK679_05445"
     CDS             complement(2..505)
                     /locus_tag="PK679_05445"
                     /inference="COORDINATES: protein motif:HMM:NF013970.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HPC55438.1"
                     /translation="MHSLLHIPSNTRVIFDTNILVYWVTDHPRFGKHCTEIVTRVEKG
                     EIQGVIPAIILNELLHRIMIAETIETGYARNFQDAVKILKDDPSIIKEMTIAGIVYGT
                     LPTIGFEMIEDERGISSLTYYFSKELCLMAKDAAIVAYAHKYDISNIVTNDRDFQRVQ
                     WLTCWSP"
     gene            complement(498..851)
                     /locus_tag="PK679_05450"
     CDS             complement(498..851)
                     /locus_tag="PK679_05450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55439.1"
                     /translation="MTFETFGLNEAYKRVQKVGDRLSVKKALAVGFITHAYTIASIRL
                     MSRKRQLKYGITEMPPIEVHRRVERNFIKSTRGKSVPALEKEEEGSHAQKLSGILKIK
                     DPRIIEEIAESDLLA"
     gene            complement(977..1048)
                     /locus_tag="PK679_05455"
     tRNA            complement(977..1048)
                     /locus_tag="PK679_05455"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1014..1016),aa:Thr,seq:cgt)
     gene            complement(1204..1500)
                     /locus_tag="PK679_05460"
     CDS             complement(1204..1500)
                     /locus_tag="PK679_05460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3467 domain-containing protein"
                     /protein_id="HPC55440.1"
                     /translation="MTSHEIAVNIPNTLDPVYSNMIQIAYKEDEFTFVFLHQIPGVNQ
                     ARAKAIVSITPQHAKTLLAVFSKTMADYEAKFGKVESSGGKQEGESVTTIRGYS"
     gene            1639..2334
                     /locus_tag="PK679_05465"
     CDS             1639..2334
                     /locus_tag="PK679_05465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="Dna2/Cas4 domain-containing protein"
                     /protein_id="HPC55441.1"
                     /translation="MAGGGGGGLVPVPVSAVITASFCPMRLYLERRSGIARTQGSEYT
                     ICRQIASHLGEPLDAGTLWDEVLAIDPGMDPRMRTFLETCIARCTEGGPWTRPRESDV
                     PFHSDRYGLYGNIDKLFDSDPPFAIVRARPAPPAGVAGSDRLRVFGYMLLLSDAAGID
                     ASCGSVEYIPSGVPRTYFPHPIDKRRFLQALRSAREVFSGKEPARVPGPRCRSCPSHP
                     ACFPMGKRLSDIL"
     gene            complement(2499..3434)
                     /locus_tag="PK679_05470"
     CDS             complement(2499..3434)
                     /locus_tag="PK679_05470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HPC55442.1"
                     /translation="MKVQKPIRLRDFIEDGDGWLYAVSTYDNSERAGCTLRYVPDEEG
                     DRVTGDGRRYRKVDFDEAFSLVAHKKPAYRDVFHRVPLSDIRRVLKPEEEIDRIAARD
                     ARVRRLLSLFSLPPGSIGCTGSFLCGLENEASDIDLVVYGDYWFRAVEILRDATGNGL
                     LEPIDEAMWRRIYEKRKPELGFDEFLIHEKRKWNRGKIGTTYFDILYTRSYADALCVP
                     HAKGRVLGRGTIEATVTDARFSHDSPAVYRVDHGEVSSVLSFTHTYSGQAREGEVIEA
                     RGVLEEHGGDVWLVVGTSREAKGEFIRSLTLLGED"
     gene            complement(3431..4012)
                     /locus_tag="PK679_05475"
     CDS             complement(3431..4012)
                     /locus_tag="PK679_05475"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HPC55443.1"
                     /translation="MNRLEAAARIIRQDGLVVYPTDTIYGLGADAFSDEAIQKVFDAK
                     RRPFSQPISVAVNDIEMVFGIGYVDETALEFIGRFLPGPVTVVIPARNSVPESLTGGM
                     GMIGIRIPNHPVALELIALVDTPITATSANIHGARDPVTPDECHVPHDILLDAGRLPG
                     TPSTVVDLASRRILRRGAMEAEVAAFLRELGGE"
     gene            complement(4015..4695)
                     /locus_tag="PK679_05480"
     CDS             complement(4015..4695)
                     /locus_tag="PK679_05480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5612 domain-containing protein"
                     /protein_id="HPC55444.1"
                     /translation="MDDQDRDLFALRIIAENEKGVLRDIATVVAGHNANILMIHQEIF
                     DSGPWNGMAELYMEYDGCPDTGEMVRHLLALPSVREAKVVEPFSHIYGTRVIIIGGGA
                     QVAQVALGAVNEADRHNIRGERISVDTIPLVGEKTVAQAVDAVARLPRAAILVLAGSL
                     MGGEISRAVDRVREAGIPVIALKMAGSVPRHADMVVTDPIQAGVFAVMHVSSKAVFDI
                     NRVRGKEF"
     gene            complement(4704..4774)
                     /locus_tag="PK679_05485"
     tRNA            complement(4704..4774)
                     /locus_tag="PK679_05485"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4740..4742),aa:Gly,seq:ccc)
     gene            complement(4920..5837)
                     /gene="aglJ"
                     /locus_tag="PK679_05490"
     CDS             complement(4920..5837)
                     /gene="aglJ"
                     /locus_tag="PK679_05490"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer glycoprotein N-glycosyltransferase AglJ"
                     /protein_id="HPC55445.1"
                     /translation="MAISKDQVCVLIPTLNEAPTVGTIVREFRQMGFPHILVMDGNST
                     DGTRGIAEREGARVEVQTGKGKGRALSEAFSLIEQPYILMIDGDGTYDPADAGRLLAP
                     LGEGYDHVIGDRLTEENRHAFSRLNYFGNFILNRLFKTAHSAFLSDILSGYRAFSRES
                     VLQMNLREAGFGIETEISAEAVRRRQKIAVVPVSYRKRPGTPTKLNPFHDGFKITATI
                     WRLARMSNPLFYFGLIGLVIMTAGFFVGIYIIWEWLRHVEHLPLTILTVLLIIAGFQI
                     FMFGILSDMMLAMHREIISEIHEFRQKNR"
     gene            5878..6456
                     /locus_tag="PK679_05495"
     CDS             5878..6456
                     /locus_tag="PK679_05495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF99 family protein"
                     /protein_id="HPC55446.1"
                     /translation="MHIAKKGLRVLGIAESFSSRSTSLLAGVVMRKDLRIDGVAVTGV
                     TVGGMDATEGVLALVRDLDRKDINCIFLGGCIIAWYNIIDPQEVLHRTGLPVVVITYR
                     KSEGIHDKIEALFPGDSRRLSCYDSLEKPVPVTLPSGHVVHLRAVGIGLPDATRLCRD
                     FILDGRLPEPVRVARLVARAVMRHGFSGQAGN"
     gene            6521..7051
                     /locus_tag="PK679_05500"
     CDS             6521..7051
                     /locus_tag="PK679_05500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HPC55447.1"
                     /translation="MENSSQTGKPYFGFIRSPVRLLAAILVCNLAGVIGSVFTVTGPG
                     SWYASIVKPSFNPPGFLFGPVWTTLYTLMGISLYLVWMEGLSGKRVTTAVIIFGIQLG
                     LNIVWSFLFFGLRSPFLGLVEIIILWVFIAATIVLFHRISRPAAYLLVPYILWVTFAS
                     FLTYTIWTLNTPVAGV"
     gene            complement(7026..7502)
                     /locus_tag="PK679_05505"
     CDS             complement(7026..7502)
                     /locus_tag="PK679_05505"
                     /inference="COORDINATES: protein motif:HMM:NF020950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease inhibitor I42 family protein"
                     /protein_id="HPC55448.1"
                     /translation="MKSPAHYALVVLALFVVLAGGAAAARLSFGESDNGKTVSAFPGD
                     TIVLSLSENPSTGYRWVMETSGCIALVASSYTPSDTGRIGAPGTRVWRFIVNGTGPGE
                     ISAVYRRPWMQDSGSGERFALHIISAKKGIPNRESSPFFFKKTLRNTFFIPRPRAY"
     gene            complement(7606..8301)
                     /locus_tag="PK679_05510"
     CDS             complement(7606..8301)
                     /locus_tag="PK679_05510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55449.1"
                     /translation="MVPVPVIEVGEGEFRLNTFLRTYWYLFIFIAFFCAITIILALTF
                     LPITGTTATFSIIGVTFDLQAISIGASLLVTYLGVSTILWTAFEKPVARPIFYYFIGI
                     EAFKRLLLLIPLVSLVLALTIWIYTLYPGVLIVIFALVGFCAGLVVFASVLVLISRAS
                     SVRNIVMVTITYALVVFFVTLGLLLFIDIRSLPDYFSPFTLFLFAMGIASVFYILMTL
                     IFEIIMPVFSKVH"
     gene            8454..9212
                     /locus_tag="PK679_05515"
     CDS             8454..9212
                     /locus_tag="PK679_05515"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55450.1"
                     /translation="MISILLVDDEVQFLEITKMFLEKGRGIRVTTATSGDEALEILKS
                     QKFDAIISDYAMPGMNGIEFMKRVKTLGDDTPFIIFTGKGREDVVIDALNFGADLYLE
                     KNPDVRGQVSDVLVKVKNLVSSRSGDREERERCRQLHNLMERLSCATFRIKEGAHEAY
                     ILAGDASSSFLPASLCQGRIVKSDILGLAHPEDREKIRNTRSEAFRKARDYRIKYVML
                     REGGEERRVMERGFPALRPDGYFIEGYIIDLDSF"
     gene            complement(9209..11053)
                     /locus_tag="PK679_05520"
     CDS             complement(9209..11053)
                     /locus_tag="PK679_05520"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55451.1"
                     /translation="MRILLVDDDPMLPDLIRKFLEREGEIEIEATRSGSEALEKISQE
                     KFDAIVLDYELPGMNGIDLLRMIKRRGDDIPAIIFTGKSREEVAIRALNYGAEYYLQK
                     KGDPRHNFLELLSMIREAVRKHRAGLELKESERRFRESLENARLIAFQLDRNLFVIFC
                     NDYFLGIAGYRREDVLGRSFVELFVAEGERQKVQQMFFSALREEPGSGYFTCSIRTAK
                     AETRRIALNCSVLKDSSGNSVGITCIGQDITEKEKAEEEKAESEERLKVLFEYAPFPY
                     FITDLKGTFLDGNHAAELLVGYSRRELIGRNFLESGLLSPEEVPKAIALLAKHIRGEA
                     TGPEEFTLIRKDGSLVVAEIRNQPVRVKGQTLVLGSVHDVTGRNAAEESLRRANAKLT
                     LLNIITRHDILNTVTALLLYIELLKESPKDDAQKETISRIEMLAQTIKRQIEFTKVYQ
                     DIGMGNPQWQALGPIVERVKNSIPLPGVTVSHDTGGIEVYADPLLEHVIHNLIDNSLR
                     HGNGVSSIWITTLQDEMGLKIVYEDNGQGIPPREKENIFKRGYGKNTGFGLFLAREIL
                     GTTGLQIKETGTYGKGARFEIRVPRGLFRISGKGEEEEGGGGSAPVET"
     gene            complement(11264..11629)
                     /locus_tag="PK679_05525"
     CDS             complement(11264..11629)
                     /locus_tag="PK679_05525"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55452.1"
                     /translation="MRQVPVSVLVRAGIARRSGRGISLSLDEGIFYLTEEDFAHLVSG
                     RNAAVINGQGEWEGNAWLSPVLASRKSELTILLHNRLFSVGMRHLNSLLQGERNSVVI
                     REYRGHSGNAMPARGTPLT"
     gene            complement(12244..13986)
                     /locus_tag="PK679_05530"
     CDS             complement(12244..13986)
                     /locus_tag="PK679_05530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2070 family protein"
                     /protein_id="HPC55453.1"
                     /translation="MSLPVVGGEVRIERLARYLFNAPSWPVSLVILCILGVILDAVTL
                     RIGETPFLGTLLFTVPALCAFLLTKPLVSLLGRPMTWNRSALLALSCAVFGMLIVLCG
                     IIISRPLIGLAYAIALGFTLGLRLLVLVAIADYRITRMIVPSATESLPGILVGALVME
                     SPFLPLSLLLQLLFCAGFIVLIWLIDRPLYRAFHVRGLDFINSFLAHLTDGSRALEGY
                     FEKIGEEVTVPQVSIFFSRKGRRGLLITIPNVHPGPVGEIGGGNLPKGMQAGFEEMVM
                     VPHGAATHDFNPVSEKEIDKLADAVRKTRGSLRYSPLASKSVRFSEGSVSLLCQVFDS
                     TLLIVSTRSPERTEDIDFNIGMTIMGEGHRFFENVGFIDAHNCSAGDVSYVLPATRLA
                     MEYYRAGMKAIGEMPGKPREPMELGIARVSVPFSREQGFGDNGIQIALVRTRNQTTAY
                     VLFDGNNMEAGVREAIRDFLLSRVDEAEVMTTDSHVVNTVRGRNPVGLHVPVEEIIPW
                     VEKALSEAFSDLSPAEAAGSTAWCEGIRIFGSHRITQMASTVNTMLIFIPFISAGMLL
                     LVFILSVLAYILIG"
     gene            complement(13983..14906)
                     /locus_tag="PK679_05535"
     CDS             complement(13983..14906)
                     /locus_tag="PK679_05535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HPC55454.1"
                     /translation="MIYVVGHTAIDHICRIRDFPPPNGSVTIEERKVFFGGGAANIAA
                     GIARLGVPCTLVSAVGDDFSGSDYDRWQKSLGIGQEFFRVEGAHTPTAFMFTNEKGDQ
                     ITFFEWGASGIFATAPAPALPFVHMATADPDFNVRVAQKARFCTFDPGQDLHRYSAHQ
                     LESILSRVVILFANQHEVEGMCRTLGLTKEALSARVPIAVFTAGAAGSDLFMGRDHVH
                     IPAVRVKMADPTGAGDAYRAGFLAAYDRGYAVPDCCRIGSVTASFAVEVPGCQTNLPT
                     WEMVRDRYAAHFGPFPEPSARDSVQAGRDRE"
     gene            complement(14903..15241)
                     /locus_tag="PK679_05540"
     CDS             complement(14903..15241)
                     /locus_tag="PK679_05540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF555 domain-containing protein"
                     /protein_id="HPC55455.1"
                     /translation="MPDYSVILEGAFIVRDVSSLDDAVSIAISEAGKRLNPVAAYVDV
                     EVGMLACPFCEGELNSALVVAKTALVGLLLEMKVFRAESPEHATRIARSVIGKALKDV
                     PLQVKEVCPL"
     gene            complement(15252..15779)
                     /locus_tag="PK679_05545"
     CDS             complement(15252..15779)
                     /locus_tag="PK679_05545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HPC55456.1"
                     /translation="MDSSEFHEFLLSRSSVREFRDEPVPEVDITYILDCASTAPSAGN
                     LEAWDVVLVTGRDIREELSDAAYGQEHVRDAPLLLVVCANYVRSMSQYGERGILFALQ
                     DATIACTYMMLAAHARRLHSCWVGAFVEEDVRTVLGLPAHVRPVAILCVGRGHPPGRL
                     TERLPVGEHVHSNAW"
     gene            complement(15766..16266)
                     /locus_tag="PK679_05550"
     CDS             complement(15766..16266)
                     /locus_tag="PK679_05550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55457.1"
                     /translation="MRHDSGFFSPGIRGYPGVSCRERGNAGKESVIALPLQKYIVSRH
                     GRKNMDPKAAIRNYQFAERAKSELIICSQLTIALAGFPEQERPGGKRMLVLLLEAVRS
                     ELEFAWRGTESQEFRKAINLLSESISIVESDNYGGASLKISESISAVTTAAQAAWQVL
                     GEHGLV"
     gene            complement(16344..16673)
                     /locus_tag="PK679_05555"
     CDS             complement(16344..16673)
                     /locus_tag="PK679_05555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5350 domain-containing protein"
                     /protein_id="HPC55458.1"
                     /translation="MGKTGSVQWTQVKGVKGQIRLVPRAEGEVKKPGPNQRFKAGASL
                     KKLEEASGEGQGGYRGRSGGRGGRGGRGGGRGRSSEPGPVANPMVRRAMRRSKASILG
                     AKQKSSR"
     gene            complement(16749..18605)
                     /gene="gatE"
                     /locus_tag="PK679_05560"
     CDS             complement(16749..18605)
                     /gene="gatE"
                     /locus_tag="PK679_05560"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu-tRNA(Gln) amidotransferase subunit GatE"
                     /protein_id="HPC55459.1"
                     /translation="MGNEEQGLKAGIEIHQQLNTREKLFCHCPPVLRPFEERNGEFFR
                     YLRATESELGEIDRAAEEEMKNLRRFCYYTYDTTCLVENDEEPPAPLNREALFICLQI
                     AKMCGMTPVPQVHTMRKLVIDGSNTSGFQRTALVAVNGTLPGGVPIETICLEEEAAQR
                     VEGDTFSLDRLGIPLVEITTAPTMRTPEEVAEVARYIGMVLRSTGMVRRGLGTIRQDI
                     NISIPGGARVEIKGVQELDLIAEVVRREVQRQRNLLSLRDRLLARGARVDPTTRDVSS
                     LFSKTKSSILKKAPCILAVLLPGFGGLVGEEIQPGRRLGSEFSDYAKKCGVGGIFHTD
                     ELPAYGITAEEVEALRNATGAREGDCVVIVAADARRAECACRQVIRRAGLALAGVPEE
                     TRRMEEGGNTSYMRPLPGAARMYPETDVLPVRITGDYWDSIPVPELLEKRAARFAGEL
                     GLDPALAWQVVYSEYLPLFEEAVRRGVAPPLAARTILATVKEIARDGLDTGALLEPQK
                     TRGDPAVLTVLLAVAQGRLAKEAVPQVLRSVCQGTDVTLAIAALETRIDDAQLRAIAD
                     RLVQERIAFVREKGQSALGPLMGPMMKEVGGTVDGKKVSQVLRDAIRDALGG"
     gene            complement(18581..19831)
                     /gene="gatD"
                     /locus_tag="PK679_05565"
     CDS             complement(18581..19831)
                     /gene="gatD"
                     /locus_tag="PK679_05565"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu-tRNA(Gln) amidotransferase subunit GatD"
                     /protein_id="HPC55460.1"
                     /translation="MNVFVPGDRVSFSLGGQPGTGTYITERDGMAVLKLDSGYNIGIP
                     PEGCTLLERVEAPRPVTKEVSQDPSLPQLSIISTGGTIASRIDYRTGAVTSQFDAADI
                     LRAIPGLRDIARYTTRKISTILSENMTPALWRELARAVFAEIRDGARGVIVTHGTDTM
                     GYSAAALSFMLDTPVPVVFVGSQRSADRPSSDNQMNALCSARVGVSDLSGVFVVMHDT
                     TSDERCAIHRGTRVRKMHTSRRDAFRTLGAPPLGYVSYPDLEVTLSPGATRRGEEEPA
                     LHDRLEERCALVQFYPGMPPESLRSFDSYRGLVISGTGLGHVSSGMVPVIGDLIEGGT
                     MVVMTSQCLHGRVCDRVYDTGRDLLKAGVIEGEDMLPETALVKLMWVLGNAKDGEEAR
                     ALMQRNLKGEYLPRSLAWETKSRA"
     gene            complement(19828..21318)
                     /gene="argH"
                     /locus_tag="PK679_05570"
     CDS             complement(19828..21318)
                     /gene="argH"
                     /locus_tag="PK679_05570"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HPC55461.1"
                     /translation="MERKTEDVVRRGRLKGERSGEMMHFLSSMDADRCIADADILVDM
                     AHVLMLAKKNIIGKETAKQLLGALLGLYDNGIPDFVFDDRFEDIHAGIESYLVSSIGE
                     DAGGRLHIGRSRNDEVATCIRMRVREDIARQLAILVSLRGILLDLAGDHTGTVMPGFT
                     HLQHAQPTTLAHHLLAHEAAFARDFERLCGAYSRTNRCPLGAAAFASTSYPVDRELVA
                     SLLGFDGILDNTMDAVASRDFALEVLSDLSILMTHASRLCEELVLWSSRFVRFVELDD
                     AFCSTSSIMPQKKNPDSAEVMRAKAGSVLGAAVAAQAIMKGLPMSYNRDLQELTPALL
                     RGIRDAKHSTRILADMLSSASFNTEEMAAEAGRGYSTATDLADLLVQKYGMAFRTAHT
                     LVGRAVSKGSLDLATLDRVAREEGFSPLSDLGLTQQEIDAALDPVAAVDRRRAPGGPS
                     PFAVKVSLSERRAVLDRDSRFLDEKRNALSEAVRRLIADVRREAGA"
     gene            complement(21349..21879)
                     /locus_tag="PK679_05575"
     CDS             complement(21349..21879)
                     /locus_tag="PK679_05575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC55462.1"
                     /translation="MIADPVEKVIRAALVSDEEFSLVLRDVMKRDLRISVKELSEASG
                     IAPSSLYKIVHGQRSPNLSTLRAIVNAMRRVTRLPDGEFIGLIAARPVLDVVQERNAV
                     VDNRRVRVREYPVHTMEEAIISALRAEREGAIAIVCAPIVSSVIEQIVNVPVATIIPR
                     DSVQRAIELAARKAWI"
     gene            22062..23279
                     /locus_tag="PK679_05580"
     CDS             22062..23279
                     /locus_tag="PK679_05580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HPC55463.1"
                     /translation="MKLNPLHLVAGLLVCTLLFAGCTTTTTPPPATSGGTVILTYTKG
                     TGPMPTLLGTNQIDGYIAWQPFVEVAPLARIGKVLVYSGDMPPEGRWKNHPCCVFTAT
                     SDAISGSPDMTNALTAALVLSTRYLGDHPDESAEIVADWLAGKGNFTYGDISVSSVEV
                     LQRAFPTVKFVNEPTDAWKKSNLEFVYAQRELGVLTGSLKNSTDAETLSLLFDSKPYD
                     EAKAMIDAGRITTPAPAKDPVGIGYLMSDHHAALFVAIKKWQYFNDTYGICIKPRDTT
                     ASRPDVADLIVNGQKVAELKLVPGDAGPQLMQLMATGNIRYALVGNPPAIAAADKGTP
                     VKIIMALNGEGSGVVVSNGSPAKDWAGFVAWANERSAAGKPVRIAAPGKGSIQDVLMR
                     YALEASGLSVREG"
     gene            23292..24056
                     /locus_tag="PK679_05585"
     CDS             23292..24056
                     /locus_tag="PK679_05585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55464.1"
                     /translation="MRYQRVLLPIILVVAWEIAALAINNPFILPSLETVVPILINPFS
                     ASFTLGTGSLAENAAISIERVGLGFLLATAIAIPLGVLMGRSRALNDFFDSLIEILRP
                     IPPLAWVPLALAWFKIGLTSIVFIIFIGAFFPILLNTIDGVKGVKKTWIEVATTLGAS
                     ERQVLLKVVLPGAAPTVWTGLRVGFGIAWMCVVAAEWLPGISRGLGYLILYAYNFGQT
                     NLIIAGMVVIGLIGLAIDLVFKKVEKKWFSWRGLER"
     gene            24091..24849
                     /locus_tag="PK679_05590"
     CDS             24091..24849
                     /locus_tag="PK679_05590"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55465.1"
                     /translation="MALVLDSISKSFSLADGSTVDALSGISLAVADSEFVSVLGPSGC
                     GKTTLLRIIAGLETPTSGTITLDGERIAGPSPRMAMIFQEYSLYPWRTVIDNIEFGLE
                     IRGMTREERKKRAIEYLDLVGLRDFAGRFPYELSGGMRQRVAVARALAIDPAILLMDE
                     PFGALDAQTRNRLQRELLDIWEKTRKTVLFVTHSVDEAVYLSDRIVVLTPRPGRIREI
                     VPIGLPRPRERTDVEFARIRRYVLDHVENMAATR"
     gene            24910..25446
                     /locus_tag="PK679_05595"
     CDS             24910..25446
                     /locus_tag="PK679_05595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HPC55466.1"
                     /translation="MVRKPGKMYRNLAKKAYTRKEYMGGIPGSKVVQFDMGNLTDEFP
                     VQLSLAVEEGCQIRHTALEAARISINRRLIKDVGRMNYRLKLRVYPHHVLRENKQATG
                     AGADRVSEGMRLAFGKAVGTAARVMPGQEVFSVYTTPQFLDKAKEALRSGSHKLPSPT
                     RIIIRELPVSKAPAAEQA"
     gene            25725..26561
                     /locus_tag="PK679_05600"
     CDS             25725..26561
                     /locus_tag="PK679_05600"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HPC55467.1"
                     /translation="MIPSPDDALCAALTRATCRALEQAEIFLPPDVVRALEAARDRET
                     SGIARGEIENILSNIRMAESLRVPICQDTGVPVIYLTLPPGIPLSGTLLDAVAEGVRL
                     ATRTIPLRPNVVDPLTRKNTGDNTGPGMPAVHVRHGERLTVTALPKGAGAENMSRVAM
                     MLPTDTGNVARFVAETMLIAGGKPCPPVVLGVGIGGTFDGAAAAAKEALLDPIDTMTE
                     YERGLLDAVNDLCIGPMGLGGKTTALAVKVKGAGCHTASLPVAVNVQCWACRRATVEV
                     EW"
     gene            26558..27124
                     /locus_tag="PK679_05605"
     CDS             26558..27124
                     /locus_tag="PK679_05605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FumA C-terminus/TtdB family hydratase beta
                     subunit"
                     /protein_id="HPC55468.1"
                     /translation="MTRIDLSTPLSHEVLMLRAGDHVTLSGTVYTARDEAHLRMREEG
                     IPFDPHGAAIYHCGPVIHEGRIIAAGPTTSARMNALSGFLLEQGVRALIGKGGMSRQV
                     ADQMKGRAVYLAFTGGCAALAASRMTLRRVFFEDLGMAEAVYEIDLDHLPLVVGIDAA
                     GNDLFEGVNRNAQARFKKRFSLSREAVP"
     gene            27121..27393
                     /locus_tag="PK679_05610"
     CDS             27121..27393
                     /locus_tag="PK679_05610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HPC55469.1"
                     /translation="MKLVIDEKRCKGCNLCTMVCPYKIYKPGKKPNERGIVVPELDRP
                     ERCPNCRLQALYGRTLCGMCQMICPDQAISWVEEKPGEKKKVAIEF"
     gene            27390..28490
                     /locus_tag="PK679_05615"
     CDS             27390..28490
                     /locus_tag="PK679_05615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="HPC55470.1"
                     /translation="MTRIEFMQGNVACAEGALAAGCSFFAGYPITPSTEIAEHMAARL
                     PKKGGVFIQMEDELASIAAVIGAAWTGARAMTATSGPGFSLMMENIGFAAMTETPCVI
                     VNIQRGGPSTGQPTMSAQADMMQCRFGSHGDYSIIALSPASVQEMYELSAEAFNLADR
                     FRVPVFLMADEIIGHLRERIEIPDSVQKTERKPLPPGELPFHPGDDLVPGFPRFGAGH
                     GVHVTGLTHDERGYPCATNPKVHEELVRRLVEKVESKRHEIADYRVTNPDAELVFVTY
                     GSPARSVEQVLHDNPEKTIGHLRFRIVWPFPENALREFPNARAFLVPEQNLGQMAREI
                     ERHTTVPVIRLPRFGGALHTPEELVAALEGLA"
     gene            28487..29275
                     /locus_tag="PK679_05620"
     CDS             28487..29275
                     /locus_tag="PK679_05620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HPC55471.1"
                     /translation="MTYTDWLRADRLPHIYCAGCGNGTVINCTLNAVVQAGLKKEETV
                     FVSGIGCSSRAPGYIVTDSLHTTHGRALAFATGIKMANPALSVIVFTGDGDLAAIGGN
                     HFIHACRRNIDLTVVCMNNMIYGMTGGQGSPTTPRMALSTTTPYGSAEPAFDLCELAI
                     AAGANYVSRWTSYHVKELTRAILAGLRTPGLSFIEAMVQCPTNFGRRNRYRQPLDQVE
                     YFKAHGMLVEKVRRMQEEGREIPPDTIVLGELARRNRPAMGVKP"
     gene            29272..29811
                     /locus_tag="PK679_05625"
     CDS             29272..29811
                     /locus_tag="PK679_05625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit
                     gamma"
                     /protein_id="HPC55472.1"
                     /translation="MRHEVRFSGFGGQGIILSAVILGRAAVMYDGNYAVQTQVYGPEA
                     RGGASMSSVIIDDAPILYPKVRDPDILVIMSQEGFEKYGANAAESAFMILDSSLVRSR
                     PRCRYLGIPATTEAKNTLGREIVANIVMLGALVRATGIVREESLEKAILDSVPKGTES
                     LNVRAMKRGMELASGEKGQ"
     gene            29808..30893
                     /gene="sucC"
                     /locus_tag="PK679_05630"
     CDS             29808..30893
                     /gene="sucC"
                     /locus_tag="PK679_05630"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HPC55473.1"
                     /translation="MKLLEHEARKIFAEHGIPVPAGSVIRSPGELATVMDTLGDRIVL
                     KAQVEVGGRGKKGGVLVADRSNAQELASRLFSMEIGGIPVREVLAVEYLDIRHEYYLS
                     ISVDRSRKCALILFSDQGGVDIESLARDRPDALRRAAIPVLMDRVPPFMIRDLLSGAP
                     AEIGDVINRLYSVFCRKDALLAEINPLVMTPAGLYAADAKLVIDDNALRRQGIAQNRD
                     LTEREREAEKHGFSYVELKGDIGVIGNGAGLTMATLDLIQYYDGSAANFLDVGGGADQ
                     ERVMHAVRLVAADPSVRVIVVNLLGGITRCDEVARGIIAAGVSQPVIVRLAGTNEKEG
                     REILRSSGYQMLDSMEEAVRAAVEATR"
     gene            30890..31756
                     /gene="sucD"
                     /locus_tag="PK679_05635"
     CDS             30890..31756
                     /gene="sucD"
                     /locus_tag="PK679_05635"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HPC55474.1"
                     /translation="MIYADKDCGVIVTGATGKQGVFHISLMNSYAREVGGRGVVAGVT
                     PGKGGQEVAGVPVYNSIREALREHDATVSVIFVPAAAAADSIMESASAGMSLAVAITE
                     HIPVHDTMKAIAFAHLHDCAVIGPNCPGLLSPGAIKLGIMPVHLSMRGHVGVISRSGT
                     LTYEIVDQLTRAGLGQSTIVGIGGDPVIGQTFTDVLRRFEEDDQTRAVVIIGEVGGSL
                     EEEGAKSTDLPVAAYIAGVSAPPEKRMGHAGAIIEGGEGDARSKIERLQKMGVPVARR
                     PSEIPRLIRELL"
     gene            31857..32696
                     /locus_tag="PK679_05640"
     CDS             31857..32696
                     /locus_tag="PK679_05640"
                     /inference="COORDINATES: protein motif:HMM:NF024637.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HPC55475.1"
                     /translation="MTEYQTGEGDPFGEDEVLTGPARYLRPGEELLVYTPGIQIKKFR
                     FDAYLTDTRLFLTDPGEKAAGVTAKEIPRESIIDSYIEHSPAQEPILVLSIRTGEDDV
                     RTMKMTFVHTGKDRVSEAEEWMHLIKHGGPVPGAAAAPAAGITKEPAPPLSPEARALS
                     ETMVFPPPPPPQRDIPPAPRQAPARERSASVPPPPPPRPPAQSAGSTTQIQFCYHCGH
                     RIPPVANFCPYCGTRMVTPAGHGGSPAPLAPRAGAPAEPVPEKKEKKGRIWNIFRRKK
                     SEP"
     gene            32863..34065
                     /locus_tag="PK679_05645"
     CDS             32863..34065
                     /locus_tag="PK679_05645"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HPC55476.1"
                     /translation="MKRNIRVEELHQIPLERQEIELVERKCLGHPDSLADGIAESISR
                     ALSLAYLEECGAILHHNTDQGEIVAGESQPKYGGGKVIRPIYILIDGRATKQFNGISI
                     PTDAIAVEAARNYLRKTLTNLNLERDVIVDCRLGTGSTDLREVFKPCQNTPPRANDTS
                     FGVGHAPFSETETIILAVSDYIDQTLRPKYPVIGQDIKIMGLREGNTITLTLACAMVD
                     KYCAGLAEYIEFKDKIQEEALAVARKYTPRKVRVAVNTADDIDSGSVYLTVTGTSAEM
                     GDDGSVGRGNRCNGLITPNRPMSMEATSGKNPINHIGKIYNILSTQLAQECVRSVDGI
                     EEIYIRLLSQIGKPIDQPLVASVQVLPKPEFELKAIRPDIEAIIDHGLAEVTCITEKI
                     IRGEIKTF"
     gene            34043..34960
                     /gene="hisG"
                     /locus_tag="PK679_05650"
     CDS             34043..34960
                     /gene="hisG"
                     /locus_tag="PK679_05650"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HPC55477.1"
                     /translation="MARSRRSEPGRKPPVPAGGPLVRLAIPNKGRISAPVLELLEKSG
                     LHLDEGPERRLVARTPDPQVEVLFARPVDIPEYVNLGAADLGITGHDMVTERRADVAE
                     LLDLGFGSANLVLAVREESPFYSSRDLAGARVATEFPVIAGDYFEKKDIPVTLVPVGG
                     ACEATPYLGIADAIVDLSSSGNTLRSNRLRVIDHVLATSTVLIANRRSLETKKTKIEE
                     ICVALESVIRARGQCYLMMNAPRSHVAEISSILPGLSGPTVMEVASREDMVAIHAVVA
                     EERVYQLIHLLKRAGARDILVMSIERMIP"
     gene            34962..35672
                     /gene="hisA"
                     /locus_tag="PK679_05655"
     CDS             34962..35672
                     /gene="hisA"
                     /locus_tag="PK679_05655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HPC55478.1"
                     /translation="MRVFPAVDILGGNCVQLVQGRRESATVFGDPLACAQKWLSRGAD
                     CLHVVNLDGAFGRSQENVHHIRKIIRETGVEVQLGGGIRSFEDAASWLDLGVFRVILG
                     TLATKDPAVLGKLSREYGRDRVMAGLDARQGQVTVEGWQKSAGDYLDWAVRFEECGAG
                     SLLFTNVDVEGLEKGIDPRPVGALLKRTRLPVTVAGGITTISDIRLLKDLGAHAVVLG
                     SALYSGKLDLAQAMEAAR"
     gene            35669..36250
                     /gene="hisB"
                     /locus_tag="PK679_05660"
     CDS             35669..36250
                     /gene="hisB"
                     /locus_tag="PK679_05660"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HPC55479.1"
                     /translation="MRRAEVIRETNETRIALELDLDDPGSGEIATGIAFFDHMLASMA
                     RHGHFFLSCRAEGDLDVDAHHTIEDTGIVLGQAFRQAIGDGKGIVRFAHALIPMDEAL
                     ACAALDCGGRGYLVFKGEFSHQKVGGVEREIFEHFFYSVCIRGGITANLSMEGKNDHH
                     KCEALFKAFGIALGQATRTGPWPQTIPSTKGSL"
     gene            36380..36670
                     /locus_tag="PK679_05665"
     CDS             36380..36670
                     /locus_tag="PK679_05665"
                     /inference="COORDINATES: protein motif:HMM:NF020317.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GYD domain-containing protein"
                     /protein_id="HPC55480.1"
                     /translation="MPCFIILGKLSERALGRMKEAKDRDTQIKKVIGDAGGTLVSHYY
                     TIGRYDVVMTINLPNEEILAKVLIGIGKFGTVSTETMTALLPEQMYRMATGT"
BASE COUNT         7271 a        11329 c        10906 g         7173 t
ORIGIN      
        1 ttcacggact ccagcaggtg agccattgga cccgctggaa atcgcggtca ttcgtaacga
       61 tattagaaat atcgtatttg tgtgcatacg ccacaattgc cgcatccttt gccatcaggc
      121 acagttcttt tgagaaataa tacgtgaggc ttgagatccc cctttcatcc tcgatcatct
      181 caaatcctat cgtcggcagg gttccataca ctatccctgc gatggtcatt tccttgataa
      241 tcgaaggatc atctttcagt atcttgactg catcctgaaa attacgtgcg tatcccgtct
      301 caatcgtctc tgcaatcatg atacggtgga ggagttcatt gagaatgatt gccgggatta
      361 ctccctggat ctctcctttc tccacccgag tcactatctc ggtgcaatgt ttcccgaacc
      421 ggggatgatc ggtcacccag taaacgagga tatttgtatc gaaaataacc cgggtattgg
      481 agggaatatg aagaagacta tgcaaggaga tcactttcgg cgatctcttc gataattcgt
      541 ggatctttta tcttgagaat accagagagt ttttgagcat gggaaccctc ttcttccttc
      601 tcaagggccg gcacgctctt tcctcttgtg ctctttatga agtttctctc aaccctccga
      661 tgtacttcaa taggaggcat ttccgtaata ccatacttta gttgacgttt ccgtgacata
      721 agtctaatcg atgctattgt atatgcatgt gtgatgaatc ccactgccag ggctttcttt
      781 acagatagac ggtctcctac cttttgtacc cgtttatacg cctcatttaa tccaaacgtc
      841 tcaaaggtca ttcagaatcc ttcgatcagc tgagataaag cttttgtggt ttgagggggt
      901 gtttcgaaat ccccaatgaa aagtcggatg agtgggtata aaaaggaggg gggaggattt
      961 gaacttcttg tcctagagcc gccaggggga cttgaacccc cgacctgctg attacgaatc
     1021 agccgctata ccgctaagcc atggcggcac gatacccatt aatgtcgacg tgctgaaata
     1081 tgaaagttcg gacgggtggg gcatggtctt tgcttttcaa ggccattggt gcccggctcc
     1141 ccgcggctat ccccggaccc gcggatgtgg cgggcaaagg cccgatgact gccggaatcc
     1201 tttttaggag tacccgcgga tcgttgtgac gctctctcct tcctgcttcc cgccactcga
     1261 ctcgaccttc ccgaacttcg cctcgtaatc ggccatggtc ttggagaaga ccgcaaggag
     1321 ggtctttgcg tgctggggtg tgatactcac gatggctttt gccctggcct ggttcacacc
     1381 cgggatctgg tggaggaaaa cgaaggtgaa ttcatcttcc ttataagcaa tctggatcat
     1441 attgctgtat acagggtcca gtgtgttggg gatattgacg gcaatctcgt gggacgtcat
     1501 ggttatactg ttcagcacgg aaaggaaaaa cactttcctg cccggtgacg aaaatacccg
     1561 tcctgcaggt tccctgcaaa gaatatacgc ctcccgctgc ctttccggcg ggataccgaa
     1621 agacacgggt gacgcgtgat ggccggcggg ggaggcggcg ggctcgtccc ggtccctgtc
     1681 tcggccgtga tcaccgcgtc tttttgcccg atgaggctct atctcgagag acgatcggga
     1741 attgcccgga cccagggatc agaatacacg atttgcaggc agatagcatc ccacctcggg
     1801 gagccgctcg atgccgggac cctctgggac gaggtccttg ccatcgatcc cgggatggac
     1861 ccccgcatgc gcaccttcct tgaaacctgc attgcccgtt gcaccgaagg cggtccctgg
     1921 acccgtcccc gcgaatccga tgtcccgttc cactcggaca ggtacggtct ctacgggaat
     1981 atcgacaagc tcttcgattc ggatcccccg tttgccatcg tccgggcacg cccggctccc
     2041 cccgcgggag ttgcaggatc cgacaggctg cgtgtctttg gatacatgct cctcctctcc
     2101 gatgcggcgg ggatcgacgc atcatgcggt tcggtcgagt acatcccgtc cggggtcccg
     2161 cggacttatt ttccgcaccc gatcgacaag cggcgtttcc tgcaggctct ccggagtgcc
     2221 cgcgaggtct tttccggcaa agaaccggca cgggtaccgg gaccgcggtg caggtcatgc
     2281 ccctcgcatc ccgcctgttt tcccatggga aagagactct ccgacatcct ctgaaaagga
     2341 acctccttct tcctcgtccc aggcaggcgg aaattccggg gcgttattct gccttgagca
     2401 gtaccgggtg agtcggcggg ggaaaggctg gcgacctgcc gggagaggat ggagtgagtt
     2461 aggtttcaaa ggagtccggc ccggagaaca gggacttcct aatcctctcc aagaagagtc
     2521 agggaccgga tgaactcgcc ctttgcctcg cgggaggttc ccacgacgag ccacacgtct
     2581 cccccgtgtt cttcgaggac cccccgagcc tcgatgacct ctccctcgcg tgcctgcccg
     2641 ctgtacgtgt gggtgaagga gagaacggat gagacctccc cgtggtcgac gcgatagacc
     2701 gcagggctgt cgtgggagaa ccgggcatcg gtgaccgtgg cctcgatcgt cccccttcca
     2761 aggacgcggc cctttgcatg gggaacacag agtgcatccg cgtaggaccg ggtatagaga
     2821 atgtcaaagt aggtggtgcc gatctttccc ctgttccatt tccttttttc gtggatgagg
     2881 aactcgtcga atccaagttc cggcttcctc ttctcgtata tcctcctcca catcgcctcg
     2941 tcgatgggct cgagcaaacc gttcccggtt gcatcccgga gtatctccac cgcccggaac
     3001 cagtaatccc cgtacacaac gaggtcgatg tccgatgcct cgttctcgag gccgcagagg
     3061 aatgaacccg tgcacccgat gctccccggg gggagggaaa agagggataa aagcctcctg
     3121 acccttgcgt cccgcgccgc gatgcgatcg atctcctctt ccggctttaa caccctgcgg
     3181 atatcggaga ggggaacgcg gtggaatacg tcccggtatg ccggcttttt gtgggcgacc
     3241 agggagaaag cctcgtcgaa atcgaccttc cggtaccgcc tcccgtcccc cgtgacccgg
     3301 tcgccttcct cgtcggggac gtaacgcagg gtacagcctg ctctctcgct gttatcgtac
     3361 gtcgagacgg cgtagagcca gccgtcccca tcctcgatga agtcacgcag cctgatgggt
     3421 ttttgcacct tcattcccca cccagttccc ggaggaatgc ggcgacctct gcctccattg
     3481 cgccccggcg gaggatcctg cggctggcca ggtcgacgac ggtgctcggt gtcccgggca
     3541 gcctcccagc atcgaggagg atatcgtggg ggacgtgaca ctcgtccggg gtaacagggt
     3601 cgcgtgcgcc atggatgttc gcactcgtcg cggtgatcgg cgtatcgacg agggcaatga
     3661 gttccagcgc caccgggtgg ttgggaatgc ggatgccgat catgcccatg ccgcccgtca
     3721 gggattcggg cacggagttc cgtgccggaa tgaccaccgt gaccggtccc ggcaggaacc
     3781 tcccgatgaa ctcgagagcc gtctcgtcga cgtacccgat cccgaagacc atctcgatat
     3841 cgttcactgc aacggagatg ggctgggaaa agggcctcct ctttgcatcg aagaccttct
     3901 ggatcgcctc gtcggaaaag gcgtcggcac caagaccgta gatggtatcc gtcgggtaga
     3961 caacgaggcc gtcctgcctg atgatccggg cggccgcttc cagcctgttc atctctagaa
     4021 ttcctttccc ctgaccctgt tgatatcaaa aacggccttg ctgctgacgt gcatcacggc
     4081 aaagacaccg gcctggatcg ggtcggtgac gaccatgtcc gcgtgccggg ggacgctgcc
     4141 tgccatcttg agggcaatga ccggtattcc tgcctcccgc accctgtcca ccgcccggga
     4201 tatctctccc cccatcaggg accctgcgag cacgaggatt gcggcccggg gaagccgtgc
     4261 taccgcgtcg actgcctggg cgacggtctt ttcaccgacg agggggatcg tgtccaccga
     4321 tatgcgttcg ccccggatgt tgtggcggtc tgcctcgttg accgccccga gcgccacctg
     4381 ggcaacctgg gccccccctc cgatgatgat gacacgcgtg ccgtatatgt ggctgaaggg
     4441 ttcgacgact tttgcttccc tgacggaggg gagggcaagc aggtgccgga ccatttcgcc
     4501 ggtgtcggga cacccgtcgt attccatgta gagctccgcc atcccgttcc atggtccgga
     4561 atcgaagatc tcctggtgga tcatgaggat attcgcgtta tgcccggcga caacagtagc
     4621 gatatcgcgg agaacgcctt tctcgttctc ggctatgatg cggagggcaa agagatctct
     4681 atcctggtca tccattgcag gaatgcgata gccggggatc gaacccgggt tagaggcttg
     4741 ggaagcccct gtcctgccgc tagactacta tcgcacaaga aatatcgcac atacatgtcg
     4801 ctcctgttcc agataaaggt tattttgaaa ggtgccggta tcgggcaatc ccctgcaggg
     4861 aacggagggg aagaacacac gggaaagagc gaaaccctga aacgggccgc gtgaaggtgt
     4921 cacctgttct tctgccggaa ctcgtggatc tcgctgatga tctcgcggtg catggcaagc
     4981 atcatgtcag agaggatacc gaacatgaag atctggaatc cggcgatgat gaggagaacc
     5041 gtgagaatgg tcagggggag gtgctccacg tggcggagcc actcccagat aatgtaaatg
     5101 cccacgaaga atcccgcggt catgatgacg agcccgatca acccgaaata gaagagggga
     5161 ttgctcatcc gtgcgagccg ccagatcgtg gccgttatct tgaagccgtc gtggaacggg
     5221 ttcagtttcg tgggcgtgcc cgggcgtttc cggtaactga cggggacaac cgctattttc
     5281 tgcctcctcc tcactgcctc tgcagagatc tccgtctcta tcccaaaccc tgcttcccgg
     5341 aggttcatct ggaggacgga ctcccgggaa aatgcccggt agcccgaaag gatatccgag
     5401 aggaacgctg aatgggccgt cttgaaaagc ctgttgagga tgaaatttcc gaaataattg
     5461 aggcgcgaaa aggcatggcg gttctcttcc gtcagccggt cgccgatgac atggtcgtac
     5521 ccttccccga ggggagcgag cagccgcccg gcatcggccg ggtcatacgt gccgtctccg
     5581 tcgatcatca ggatgtaggg ctgttctatg agcgaaaaag cctcggaaag ggctcggccc
     5641 ttgccctttc ccgtctggac ctcgacgcgg gctccttccc gttctgcaat cccgcgggta
     5701 ccatcggtgc tgtttccatc catcacgagg atgtggggaa aacccatctg ccggaactcc
     5761 cggacgatcg ttcccacggt gggagcctcg ttgagagtgg ggatgaggac acagacctgg
     5821 tcctttgaaa tcgccatcgg gttatacttt ttttaatcct cgctcataag tccttgcatg
     5881 catattgcaa agaaggggct gcgggtcctg gggatcgcag agagtttctc gtcccgaagc
     5941 acgtcccttc tcgccggcgt ggtgatgcga aaggacctcc gcatcgacgg tgtggcagtc
     6001 accggcgtga ccgtcggggg catggacgca acggaaggtg ttctcgcact ggtccgtgat
     6061 ctcgaccgga aggacatcaa ctgcatcttc cttggcggct gcatcattgc gtggtacaac
     6121 atcatcgacc cgcaggaagt cctgcacaga accggtcttc cggtcgttgt catcacctac
     6181 cggaagtccg aggggatcca tgacaagata gaggcactat ttcccgggga cagccgccgg
     6241 ctttcctgtt acgattcttt ggaaaaaccc gtgcccgtca cgctcccctc cggccacgtg
     6301 gtccatctca gggcagtcgg catcggcctt ccggatgcaa cccgcctctg cagggatttt
     6361 atcctcgacg ggcggttgcc ggaacccgtc agggtggcac gcctggtggc aagggctgtc
     6421 atgcgacacg gtttttccgg tcaggcagga aactgaagag aaccgctcgt gccgtccccc
     6481 atagtcaccc ataaatagtg gcggatttca cggttaaaac atggaaaaca gttctcagac
     6541 gggcaaaccg tatttcggtt tcatcaggtc ccctgtgcgg ctccttgccg caatcctcgt
     6601 ctgcaacctc gcgggcgtca tcggttcggt cttcacggtc accgggccgg gatcgtggta
     6661 tgcctcaatc gtcaaaccct ccttcaaccc gccgggattc ctctttggac cggtctggac
     6721 aaccctctac accctgatgg gaatatccct ttaccttgtc tggatggagg ggctttcggg
     6781 aaaacgggtg accacggctg tcataatctt tggaatccag cttggtctca atatagtgtg
     6841 gtctttcctc ttctttggcc tccgctcacc cttcctcggt ctcgtggaga tcattatcct
     6901 ctgggtgttc atcgcggcca caatcgtcct tttccacagg atcagccggc cggcagccta
     6961 cctgctcgtc ccctacatcc tctgggtgac gtttgcctcg ttcctgactt acacgatctg
     7021 gactctcaat acgcccgtgg ccggggtatg aaaaatgtat tccgaagggt ctttttgaag
     7081 aaaaacggtg atgattccct attcggaata cccttttttg ctgagatgat gtggagggca
     7141 aacctctccc cgctccccga atcctgcatc cagggtcgcc ggtacaccgc ggaaatctca
     7201 cccggccccg ttccgttcac tatgaatcgc cagacacggg ttcccggcgc cccgatgcgg
     7261 cccgtgtccg aaggagtata ggaacttgca acgagggcaa tgcacccgga cgtctccatc
     7321 acccagcggt aaccggtact gggattttcg gagagagaaa ggacgatggt gtctccggga
     7381 aatgctgaaa cggtttttcc gttatcactt tcgccaaagg ataaccttgc tgcggctgca
     7441 ccgccagcga ggacgacgaa taaagccaga actacgaggg cataatgtgc cggcgatttc
     7501 atgggatggt cactcacttc cagtatcgac gccaaagtat atgatacaga ctccccgtca
     7561 tggcggggaa aacaacggac cacccagggg acaacctgct tttttttagt gaacttttga
     7621 aaaaacgggc atgatgatct cgaagatgag cgtcatgagg atgtagaaga cggaggcaat
     7681 acccatggcg aagagaaaga gggtgaaggg actgaagtaa tccggaaggc tccggatatc
     7741 gatgaagagc aggagaccca gggtgacgaa gaacacaacc agagcgtagg tgatcgtgac
     7801 catgacgata ttcctgacac tcgaagcacg gctgatgagg acaaggacgg acgcgaagac
     7861 gacgagccct gcacagaacc caaccagcgc gaaaatgaca atcagtaccc ccgggtacag
     7921 cgtgtatatc catatcgtga gggcgaggac caggctgacg agcgggatga ggaggaggag
     7981 cctcttgaag gcttcgatcc cgatgaaata gtaaaaaatg gggcgtgcaa ccggtttttc
     8041 aaacgccgtc cagagtatgg tggagacgcc gaggtacgtg acgaggaggg atgcaccaat
     8101 actgatggcc tgcaggtcga acgtgactcc gatgatggag aacgtggctg tggtacccgt
     8161 gattgggagg aacgtgagcg ccaggatgat cgtgatggca cagaagaagg caatgaaaat
     8221 gaagagatac cagtatgtcc tgaggaaggt attcaaccgg aattctcctt cccctacctc
     8281 aataaccggc acaggtacca tcgattggca gagtgtcggc gtaaaatatc atatatcttt
     8341 cttctgcgag cctttcaggg tgctgcagga tcgcctctcc tccgcgtgct ttatataaat
     8401 gaaccttcca ttttcctcgt ggcagatccg ggaggttctg cacgagggtg gcaatgatat
     8461 cgattcttct cgtggacgat gaagtccagt tccttgaaat caccaagatg ttccttgaaa
     8521 agggacgcgg gatacgcgtg acgacggcaa cgtccgggga cgaggcactg gagatcctga
     8581 aatcccagaa attcgacgcg atcatctccg attatgcaat gcccgggatg aacgggatcg
     8641 agttcatgaa gagggtgaaa acgctcggtg acgatacccc cttcatcatc ttcaccggca
     8701 agggccgcga ggatgtcgtg atcgatgcac tcaatttcgg tgcagacctc tacctcgaaa
     8761 agaaccctga cgtgcgggga caggtctccg atgtcctggt gaaggtgaag aacctggtat
     8821 cctcacggag cggtgaccgc gaggagaggg aacggtgccg gcaactgcac aatctcatgg
     8881 agagactctc ctgtgcaacg ttccggataa aagagggtgc acacgaggca tacatccttg
     8941 caggggatgc ttcttcctct ttcctcccgg catcgctctg ccagggcagg atcgtaaaat
     9001 cggatattct cggactggcc cacccggagg acagggaaaa aatcaggaat acacggtccg
     9061 aagcgttcag gaaggcacgg gattacagga ttaagtatgt catgctccgg gaagggggag
     9121 aggagaggag ggtcatggag agagggttcc ccgcgctccg gccggacggg tatttcatcg
     9181 aagggtatat catcgacctc gactcgtttt aggtttccac gggcgcggat cccccgccgc
     9241 cctcttcttc ttcccctttt ccggatatgc gaaagagccc gcggggaacc cggatttcga
     9301 accgggcccc cttcccgtat gtccctgtct ccttgatctg gaggccggtc gttcccagta
     9361 tctcgcgggc gaggaacagg ccaaaaccgg tgttcttccc gtatcctctc ttgaagatgt
     9421 tttctttctc acggggcggg ataccctggc cgttgtcctc gtacacgatt tttaagccca
     9481 tctcgtcctg gagagtcgtg atccagatgg acgagacacc atttccgtgc cggagggagt
     9541 tgtctatcag gttgtggatc acgtgttcca ggagggggtc ggcatagacc tcgattcccc
     9601 cggtatcgtg cgacacggtg actcccggga gaggtatcga attcttcaca cgctcgacga
     9661 tgggcccgag tgcctgccac tggggatttc ccatcccgat gtcctggtac actttcgtga
     9721 actctatctg cctcttgatg gtctgcgcaa gcatctcgat cctggagatg gtctctttct
     9781 gggcatcgtc ttttggactc tccttgagga gttcgatgta gagcaggagt gcagtcacgg
     9841 tgttgaggat gtcgtggcgc gtgatgatgt tgaggagcgt gagcttcgca ttggctctcc
     9901 gcagcgactc ttctgcagcg ttcctcccgg tcacgtcatg gaccgacccg agcacgaggg
     9961 tctgcccctt caccctgacc ggctggttcc tgatctctgc gaccacgaga ctgccatcct
    10021 tgcggatcag ggtgaactct tcgggccccg tcgcctcacc cctgatgtgc tttgcaagca
    10081 gggctatcgc tttgggtacc tcttccgggg agaggagccc gctctcgagg aagtttctgc
    10141 ctatgagttc cctgcgggaa taccccacga ggagttccgc ggcatggttt ccgtcgagaa
    10201 atgtcccctt caggtcggtg atgaagtagg ggaacggcgc atactcaaag agcaccttca
    10261 gcctctcttc tgactcggcc ttttcctctt ctgccttctc cttctcggtg atgtcctgcc
    10321 ctatgcaggt tataccgaca ctattccccg atgagtcttt caggactgaa caattgaggg
    10381 cgatcctccg ggtttccgct tttgcggtcc tgatgctgca ggtgaaatag ccggaaccgg
    10441 gttcctcccg gagggccgaa aagaacatct gctggacttt ctgcctttct ccctcggcaa
    10501 cgaagagttc cacgaatgac cgtccgagaa catcctccct ccggtatcct gcaatcccga
    10561 ggaagtaatc gttgcagaag attacgaaca ggttcctgtc cagctggaac gcgatcaggc
    10621 gggcattttc aagggactcc cggaagcggc gttcactctc tttcagttcg aggcctgccc
    10681 tgtgcttcct gaccgcctcc ctgatcatgg agaggagttc gaggaaattg tgacggggat
    10741 cccccttttt ctggaggtaa tactccgccc cgtagttgag tgccctgatc gcgacctctt
    10801 cacggctctt cccggtgaag atgatggcgg ggatatcgtc gccccggcgc ttgatcatcc
    10861 ggaggagatc gatcccgttc atgccgggca gttcgtagtc aaggacaatt gcatcgaatt
    10921 tttcctgcga gatcttctcg agtgcctcgg accccgacct cgttgcctcg atctcgatct
    10981 ctccctccct ttccaggaac ttccggataa ggtccggcag catcggatcg tcgtcgacca
    11041 gcaggatgcg catcgtcacc cccctctctg cccggtcatg atcaataaaa gtatccttct
    11101 cttcatattc atatcgcaga tgcctcgtgt tgcctttcgg attgcccctg cctgcgactt
    11161 cctgcacctg cagggttccg gcaacccgaa catactgccc ggcatttcct gcgccaaaaa
    11221 gggatggtct ttccgggatg gttcttcccc ttttctttcc cggtcaggtg aggggtgtgc
    11281 cgcgggccgg cattgcattc ccggaatgac cccggtactc gcggatgaca acgctgtttc
    11341 tctcgccctg caggagcgag ttgagatgcc gcattcccac cgaaaagagc ctgttgtgga
    11401 gcagtatggt cagctcgctc ttccgggacg caagcacggg agagagccat gcgttcccct
    11461 cccactcccc ctgcccgttg atgacggcag cattccgtcc cgatacgagg tgcgcaaaat
    11521 cctcttccgt caggtaaaaa atcccctcgt cgagagaaag ggatattccc ctgccggacc
    11581 gccgggcgat acctgcccgg accaaaacag aaaccggaac ctgcctcatg atgtcaccgt
    11641 gatctctatg gatccgctga ccatgtaaag gtggcgtcag acatggtgga agcctcgaat
    11701 cgtaaaaata aatgaaattt gagatttttt acgggacacc cccggtttcg ttttcctgca
    11761 ggaagtatgc gccggtgaca ggggagaccc ggacgaagga atagaaaaga gagcacgaat
    11821 cctttttcgg aacagtcagg aaatgtattc tgaaagttca attcaagcag tttaatccag
    11881 cttttggata aaaaattaga aaaactttat atagtggtca gtgtaacaga atgagtgaaa
    11941 ccagcatggt ccagggctgg aaaatgctga tactccaatt gatcgttgcc tgatactctc
    12001 acgcatcaat tgttcatcca cctggatcat gatggtacta tccttcgggg cagtatgtcc
    12061 tgactgcagc acacgtgccg ggacttctcg ttttgccgcg tgccataatg cactcatgac
    12121 ctcatccgac tggaatgtcc ggagaggaga aaaatgaggg gggaataaaa aggggatgcc
    12181 ccggtctttg tgcgtttttg cgggtcgggg accgtgacct gtcggaaaag ccccctgccc
    12241 gcatcacccg atgaggatgt aggcaagcac cgagaggatg aagacgagca ggagcatgcc
    12301 tgcactgatg aacgggataa agatgagcat cgtgttgacg gtgcttgcca tctgcgtgat
    12361 ccggtgagac ccaaatatcc tgatcccctc gcaccatgcc gtgctccctg cagcctccgc
    12421 aggggagagg tccgaaaagg cttcggatag cgctttttcc acccacggga tgatctcttc
    12481 caccgggacg tggagcccca cggggttcct cccccggacc gtgttgacca cgtgggagtc
    12541 ggtggtcatc acctctgcct cgtccacgcg ggaaaggaga aagtccctga ttgcctcccg
    12601 gacaccggcc tccatgttgt ttccgtcaaa gagcacgtat gcagtcgtct ggttccgggt
    12661 cctgacgagg gcaatctgga tcccgttgtc cccgaaaccc tgttccctcg agaagggaac
    12721 gctgacccgg gcgatgccca gttccatggg ttcccttggt tttccgggca tctccccgat
    12781 cgccttcatg ccggcccggt agtactccat ggcgagcctc gttgcgggaa ggacgtaact
    12841 gacgtctccg gccgaacagt tatgggcatc gatgaacccc acgttctcga agaaccggtg
    12901 cccttctccc atgatggtca ttccgatgtt gaaatcgatg tcctccgtgc gctcgggaga
    12961 ccgcgtgctg acgatgagga gcgtggagtc aaatacctgg cagaggaggg agaccgatcc
    13021 ttccgaaaac cgcacggact tcgacgcaag cggcgagtac cggagagagc cgcgggtctt
    13081 tctcacggcg tccgcgagct tgtcgatctc tttttccgac acgggattga agtcgtgggt
    13141 agcggccccg tgggggacca tcaccatctc ctcgaaccct gcctgcattc ccttcgggag
    13201 gttcccccct ccgatctccc cgacgggtcc gggatggacg ttcgggatcg tgatcaggag
    13261 accgcggcgt cccttccggg agaagaagat actgacctgc gggacggtga cctcctcccc
    13321 gatcttctcg aagtacccct cgagcgcccg tgagccgtcc gttaagtgcg cgaggaacga
    13381 gttgatgaag tcgaggccgc ggacgtggaa cgcccggtat aacggcctgt cgatgagcca
    13441 gatcaggacg atgaaaccgg cacagaacag gagctggagg aggagggaga ggggaagaaa
    13501 gggggattcc atcaccagcg ccccgacgag gatcccgggg agactctccg ttgcggaggg
    13561 gacgatcatc ctcgttatcc ggtagtcggc gatggcaacg agcacgagca gccgcagccc
    13621 gagggtgaag ccgagcgcga ttgcatacgc aaggccgatg agcgggcggg agataataat
    13681 gccgcagagc actatcagca tcccgaagac tgcgcaggaa agggcgagga gggctgaccg
    13741 gttccaggtc atgggacgac cgaggaggct cacgagcggc tttgtgagga ggaatgcgca
    13801 caatgccgga accgtgaaaa ggagggttcc caggaagggc gtctccccga tcctcagggt
    13861 gaccgcgtcg aggatgaccc cgaggatgca gaggataacg agggaaacag gccaggacgg
    13921 tgcattgaac aggtaccgtg caagcctttc gatccgcacc tcgccgccga caacgggcag
    13981 gctcattccc gatcccgccc tgcctggaca ctatcccggg cagaaggttc cgggaacgga
    14041 ccgaaatgtg cggcgtaccg gtccctcacc atctcccacg tggggaggtt ggtctggcac
    14101 ccgggtacct cgaccgcaaa ggacgcggtg acgctgccaa tcctgcaaca gtccggcacg
    14161 gcatatcccc tgtcatacgc cgcaaggaac ccggcccggt acgcatcgcc ggcacccgtc
    14221 ggatccgcca tcttcaccct gacagcaggg atgtggacat ggtccctgcc catgaagaga
    14281 tcgctcccgg ccgcccctgc agtgaagacc gcgatcggga cccgggcgga aagggcctct
    14341 ttcgtcaggc ccagcgtcct gcacatcccc tccacctcgt gctggttggc aaagaggatc
    14401 acaacgcggg acaggatcga ttcgagctgg tgggccgagt acctgtggag atcctgcccg
    14461 gggtcaaacg tgcagaaccg cgctttctgc gccacgcgga cgttgaaatc ggggtctgcc
    14521 gtcgccatgt ggacaaacgg gagtgccggg gccggagcgg tggcaaagat tcccgatgcg
    14581 ccccactcga agaacgttat ctggtccccc ttctcgttcg tgaacatgaa cgccgtcggg
    14641 gtgtgggcac cctcgacgcg gaagaactcc tgcccgatac cgagagactt ctgccacctg
    14701 tcgtaatcgc tcccggaaaa gtcgtcgccc acggcactga caagggtaca gggcacgccg
    14761 agcctcgcta tccctgccgc gatgtttgca gcccctccgc caaaaaagac cttcctttcc
    14821 tcgatcgtga ccgagccgtt gggcggggga aaatccctga tacggcagat atggtcgatt
    14881 gccgtatgcc cgacgacgta gatcacaggg ggcatacctc cttgacctgg aggggcacgt
    14941 ccttcaaagc cttcccgatg acggaccgcg caatcctggt cgcatgctcc ggcgactctg
    15001 cacgaaacac cttcatctcg agcaggagac ccacgagtgc cgtctttgcc accacgagtg
    15061 cactgttgag ctcgccttcg cagaacgggc aggcgagcat gcccacctcg acgtccacgt
    15121 atgccgcaac cgggttgaga cgtttccctg cctcggagat cgctatgctg accgcgtcat
    15181 cgagggagga gacgtctctc acgatgaatg caccttcaag gattacggaa taatctggca
    15241 tctgcccacc atcaccatgc attggaatgg acgtgttctc ccaccgggag ccgttccgtg
    15301 agtctcccgg gagggtgccc cctgcccacg cagaggattg ccacgggccg cacgtgtgca
    15361 gggagaccga gcaccgtcct gacatcttcc tcgacgaatg ccccgaccca gcacgagtgg
    15421 agccggcggg cgtgggccgc gagcatcatg tacgtgcacg caatcgttgc atcctggagg
    15481 gcaaagagga tgcccctctc cccgtactgt gacatggatc gcacgtaatt ggcacacacg
    15541 acgaggagca ggggcgcatc ccgcacgtgc tcctggccat aggctgcatc agagagctct
    15601 tcccggatat cccgcccggt gacaaggaca acgtcccagg cctcgaggtt gcccgcactc
    15661 ggtgcagtgc tcgcacagtc gagtatgtac gtgatatcga cttcgggcac cggttcgtcg
    15721 cggaactccc tgactgacga gcgggagagg aggaactcgt ggaattcaga cgagtccatg
    15781 ctccccgagg acctgccatg ctgcctgtgc tgcagtcgtg acagcgctga tcgattcgct
    15841 tatcttgagc gatgctccgc cgtagttgtc actttcgacg atgctgatcg actcggagag
    15901 gaggttaatg gctttccgga actcctggga ctctgttccc ctccacgcaa actcgagttc
    15961 cgagcggacg gcctcgagga ggaggacgag catccgtttc cccccggggc gttcctgctc
    16021 gggaaaaccg gcgagcgcga tggtcagctg ggagcagatg atgagctcgc tctttgccct
    16081 ctcggcaaac tggtaattcc tgattgcagc cttcggatcc atattttttc ttccgtgccg
    16141 ggatacaata tacttctgga gggggagtgc aatgacactc tcctttcccg catttccccg
    16201 ctcgcggcag gatactcccg ggtatccccg gataccggga gagaaaaatc cggaatcgtg
    16261 cctcatggca gcattcccga ggacagaccg gatttttttc ccaaagagtg ttctcttcgg
    16321 gaacgataac tgaaaaaaaa ggtttaccgg gaggatttct gttttgcgcc gagtatcgat
    16381 gccttggacc ggcgcatggc ccttctcacc atcgggttgg caacgggtcc cggttcggac
    16441 gaccgcccgc ggcctccgcc gcgtcccccg cgtcctccgc gtcccccgga acgaccacgg
    16501 taacccccct gtccttcacc cgatgcttcc tccagttttt tcaggctcgc accggccttg
    16561 aacctctggt tcggtccggg tttcttcact tcaccctccg cccggggtac gaggcgaatc
    16621 tggcctttca ctccctttac ctgcgtccat tgcacggatc cagtctttcc catagacaaa
    16681 ctccctattg aatacgttcc gggttctttt aatacttcct ttggatggag gaaacggccg
    16741 gtgccccctc atcccccgag ggcgtccctg attgcatcgc ggaggacctg cgagactttc
    16801 tttccgtcga ctgtcccccc gacctccttc atcatgggcc ccatgagcgg tccaagggcg
    16861 gactgcccct tctcccggac gaatgcaatc ctctcctgca ccagcctgtc ggcaatggcc
    16921 cggagctgtg catcgtcgat gcgtgtttcg agggcggcaa ttgccagcgt gacgtcggtc
    16981 ccctggcata ccgaccggag cacctggggg actgcctcct ttgcgagcct tccctgcgca
    17041 acggcgagga gaacggtcag gactgcaggg tcaccgcggg ttttttgcgg ttcgaggagg
    17101 gcccccgtat ccagcccgtc gcgcgcgatc tccttgaccg tggcaaggat tgtccgggct
    17161 gccagcggcg gtgccacacc cctgcggacg gcttcctcga agagcgggag gtactcggag
    17221 tagacgacct gccaggcaag agccgggtcg agcccgagct cacccgcgaa ccgggcggcc
    17281 cgtttctcga ggagttcggg gaccgggatc gagtcccagt agtcccccgt gatccggacg
    17341 ggaaggacgt ctgtctcggg gtacatccgt gcagcgcccg gcagcggccg catgtacgat
    17401 gtattgcccc cttcctccat ccggcgcgtc tcctcgggga caccggcgag ggcgagcccc
    17461 gcccgccgga tgacctggcg gcacgcgcac tccgcacgcc gggcatctgc ggcaacgatg
    17521 acaacgcagt ccccttcccg ggctccggtc gcattccgga gggcttcgac ctcttctgcc
    17581 gtgataccgt atgcagggag ttcgtcggtg tggaagatac ccccgacccc gcacttcttc
    17641 gcgtagtcgg agaactcgct cccgagacgc ctgcccggct ggatctcttc gccaacgaga
    17701 ccgccaaagc cgggcagcag gacggcgagg atgcagggtg ctttctttaa gatcgacgat
    17761 ttcgtcttcg aaaagaggga cgatacgtcc cgggttgtgg ggtcaacgcg cgctccgcgt
    17821 gcaaggaggc gatcccggag ggagaggagg ttcctttgcc tctgcacctc tctccgcacg
    17881 acctcggcga tcaggtcaag ctcctggaca cccttgatct cgacccgtgc cccgccggga
    17941 atggagatgt tgatgtcctg ccggatcgtc ccgagccccc tccggaccat gcccgtggac
    18001 cggagcacca tgccgatgta ccgtgcgacc tctgcgacct cttccggtgt ccgcatggtg
    18061 ggcgcagtcg tgatctccac gagcgggatt cccagccggt cgagggagaa cgtgtcccct
    18121 tccaccctct gggctgcctc ttcctcgagg catatcgtct cgatgggaac gcctcccggc
    18181 agggtgccgt tcacggcaac gagcgctgtc cgctggaaac cgctcgtgtt cgagccgtcg
    18241 atgacgagct tgcgcatcgt gtggacctgc ggaaccggcg tcatcccgca catcttggcg
    18301 atctggaggc agatgaagag tgcttccctg ttcaacgggg cagggggttc ctcgtcgttc
    18361 tccacgaggc acgtcgtgtc gtacgtgtag tagcagaacc gccggaggtt cttcatctcc
    18421 tcttctgctg ccctgtcgat ctcgcccagc tcgctctccg tggcccgcag gtaccggaag
    18481 aattccccgt tccgctcttc gaaggggcgg aggacggggg gacagtggca gaacagcttc
    18541 tcccgcgtgt tcagctgctg gtggatctcg atcccggctt tcaggccctg ctcttcgttt
    18601 cccatgccag tgacctcggc aaatattctc ctttcaggtt tctctgcatc agtgcacggg
    18661 cttcctcccc gtcttttgcg tttccaagca cccacatcag cttgacgagc gccgtttcgg
    18721 ggagcatgtc ctcgccctcg atgaccccgg ctttcaggag atcccggccc gtgtcgtaga
    18781 ccctgtcgca cacccggcca tggaggcatt gcgacgtcat cacgaccatc gtcccgccct
    18841 cgatgagatc cccaatcacc ggtaccatcc ccgaactcac gtgtcccagt cccgtcccgg
    18901 agatgacgag tcccctatag gagtcaaagg aacggagtga ttccggtggc ataccgggat
    18961 agaactggac gagcgcacac ctctcctcga gcctgtcatg gagggcaggc tcttcttccc
    19021 cccgccgcgt cgcaccgggc gagagcgtca cctccaggtc cgggtaactg acgtacccga
    19081 gagggggggc accgagagtc cggaaggcat ccctccgcga cgtgtgcatc ttcctcaccc
    19141 gcgtcccccg gtgtatggca caccgttcgt cgctcgtggt atcgtgcatg acgacaaaga
    19201 ccccggagag gtcgctcact cccacgcgtg cgctgcagag cgcgttcatc tggttatcgg
    19261 aactcgggcg gtctgcagac ctctgcgaac cgacgaagac aaccgggacc ggcgtgtcga
    19321 gcatgaaact gagtgctgct gccgagtacc ccatcgtgtc cgtcccgtgc gtgacgatca
    19381 cgccccgcgc cccgtccctg atctccgcaa agactgcccg ggccagttcg cgccagaggg
    19441 caggggtcat gttctccgag aggatggtcg agatcttcct cgtcgtgtac cgggcgatat
    19501 cgcggagccc cgggattgcc cggaggatat ctgcagcatc gaactggctc gtcacggcac
    19561 ctgtccggta gtcgatcctg ctcgcgatcg tgccaccggt ggagatgatg gagagctgcg
    19621 ggagggacgg gtcctggctg acttcctttg tgaccggccg gggagcctcg acccgttcca
    19681 ggagggtgca accctccggc gggatcccga tattgtaacc gctgtcgagt ttcaggactg
    19741 ccatcccgtc cctttccgtg atgtacgtcc cggtccccgg ctgcccgccc agggaaaagg
    19801 agacgcggtc acccggaacg aacacgttca tgccccggcc tcccgccgga cgtcggcaat
    19861 gagcctcctg actgcttcgg agagggcatt ccgtttctcg tcgaggaacc gggagtcgcg
    19921 gtcgagtact gccctcctct ccgaaagtga cacctttacc gcgaagggtg acgggccacc
    19981 gggggccctc ctccggtcga ctgccgcaac cgggtcgagg gccgcgtcta tctcctgctg
    20041 tgtcagcccg aggtcagaga gtggcgaaaa accctcctcg cgggcgaccc ggtccagcgt
    20101 tgcgaggtca aggctcccct tcgagaccgc cctgcccacc agtgtgtggg ccgtgcgaaa
    20161 cgccatcccg tacttctgga cgaggagatc cgcgagatcc gtggcagtgg aataccccct
    20221 gcctgcctcc gctgccatct cttccgtgtt gaaggatgcc gaggagagca tatcggcgag
    20281 gatcctcgtg ctgtgctttg catcacggat accccggagg agtgccgggg tcagttcctg
    20341 gaggtcgcgg ttgtagctca tcgggagccc cttcatgatg gcctgggccg caactgccgc
    20401 cccgagcacc gacccggcct ttgcccgcat cacttcggca ctgtccgggt tcttcttctg
    20461 cggcatgatc gagctcgtcg agcagaaagc atcgtccagt tccacgaagc ggacgaaacg
    20521 ggaactccac agcaccagtt cctcgcagag gcggcttgca tgggtcatca ggatggaaag
    20581 gtcagacagg acttcgagtg cgaagtcgcg ggacgcaaca gcgtccatcg tgttatcgag
    20641 gatgccgtcg aacccaagca gcgatgccac gagttcccgg tcgacgggat aactcgtcga
    20701 ggcaaatgcg gcagccccga ggggacacct gtttgtccgg gaataggccc cgcacagcct
    20761 ctcgaagtcg cgggcaaatg ctgcctcgtg cgcgaggagg tggtgggcaa gcgtcgtggg
    20821 ctgggcatgc tggaggtgcg taaagcccgg catgacggtc ccggtatggt caccggcaag
    20881 gtcgaggagg ataccgcgga ggctgaccag gattgcgagc tggcgggcga tatcctcgcg
    20941 gaccctcatc cggatgcagg tcgccacctc gtcgttgcgc gacctcccga tgtggaggcg
    21001 tcccccggca tcctcgccga tggaagagac caggtacgac tcgatcccgg catggatgtc
    21061 ctcgaaccgg tcgtcgaaga caaaatccgg tatcccgtta tcgtagagcc cgaggagggc
    21121 cccgagaagc tgctttgcgg tctcttttcc gataatgttc ttttttgcga gcatcaggac
    21181 atgggccatg tccacgagga tatctgcatc cgctatgcag cggtccgcat ccatcgacga
    21241 gaggaaatgc atcatctcgc cgctcctttc cccttttaac cgtcccctcc ggaccacgtc
    21301 ctctgtcttc ctctccatat ctcttcttac ataggggaaa gcaggagatt aaatccatgc
    21361 cttccgcgcg gcaagttcga ttgccctctg gacggaatcc cgcgggatga tggttgcgac
    21421 cgggacgttg acgatctgct cgatgacgct gctgacgatg ggggcacaca cgatggcgat
    21481 tgcgccttcc ctctcggcgc ggagggcact gatgatggcc tcttccatgg tgtggacagg
    21541 gtattcccgg accctgacac gcctgttatc cacgaccgcg tttctctcct ggacaacgtc
    21601 gaggacgggt cgtgccgcga tgagtccgat gaactcgccg tccggcaacc gcgtcactct
    21661 cctcatcgcg ttgacgatcg cccggagggt ggagagattg ggggatctct gcccgtgcac
    21721 gatcttgtag agcgagctgg gcgcaatccc gcttgcctcc gagagttcct tcacgctgat
    21781 gcgcaggtct ctcttcatga cgtcgcgcag gacgagcgag aattcctcgt cggacacgag
    21841 tgccgccctg atgaccttct caaccgggtc tgcaatcatg cactggcctt cctcccggcc
    21901 acacggccct gtgccccttt gtcataatct gccatggttt tttcactttt gtccataaat
    21961 attatccatt agagaaatat tttctggata attatccttt ctggctaatc attttgttgt
    22021 ttccggagaa tttaaaaggt tctgccacca cagtgtattc catgaaactc aatcctctgc
    22081 accttgtggc aggcctcctc gtctgcactc tcctctttgc aggttgcacg acgaccacga
    22141 cgcccccgcc ggccacgtcc ggtggcacgg tgatcctcac gtacaccaag ggaacagggc
    22201 ccatgcccac gctccttggg acgaaccaga tcgacgggta catcgcctgg cagccgttcg
    22261 tcgaggtggc acccctcgcc cgcatcggga aagtcctcgt ctactccggt gacatgccgc
    22321 cggagggccg gtggaagaac catccctgct gcgtcttcac cgcgacctcg gacgccattt
    22381 caggcagccc ggacatgacg aatgccctga ccgcggccct cgtcctctcg acacggtacc
    22441 tcggtgacca cccggacgag agtgccgaga tagtggccga ctggctcgcg ggcaagggca
    22501 atttcaccta cggggatatc tccgtctcct cggtggaagt cctccagcgt gcgttcccga
    22561 ccgtgaagtt cgtcaacgag ccaacggatg catggaagaa gtccaacctc gagttcgtgt
    22621 atgcccagcg ggaactgggt gtccttaccg gttccctgaa gaattccacc gatgccgaaa
    22681 ccctctccct gctgtttgat tcaaagccct acgatgaggc aaaggcgatg atcgacgcgg
    22741 gcaggatcac gaccccggct cccgcaaagg atcccgtcgg tatcgggtac ctcatgtcgg
    22801 accaccatgc cgcactcttc gttgccatca agaagtggca gtacttcaac gacacctacg
    22861 gcatctgcat taagccccgg gacacgacgg catcccgccc ggacgttgca gacctcatcg
    22921 tgaacggcca gaaagttgcc gaactgaaac tcgttccggg cgacgcggga ccgcagctga
    22981 tgcagctgat ggccacgggt aacatccggt acgctctcgt cggaaacccg cctgccattg
    23041 cagcggcaga caagggcacc cccgtcaaaa tcatcatggc cctcaacggg gaaggatccg
    23101 gagttgtcgt cagcaacggt tcaccggcaa aggactgggc tggtttcgtt gcctgggcaa
    23161 acgagaggtc tgctgccggc aagcccgtca ggatcgccgc acccgggaag ggatccatcc
    23221 aggacgtcct gatgcggtac gcgcttgaag caagcggttt atctgtcagg gaagggtaac
    23281 ctaaggggat aatgaggtat cagcgggtcc tcctccccat cattcttgtg gtggcatggg
    23341 aaattgctgc ccttgccatt aacaacccct tcattctgcc atctctcgaa accgtggtcc
    23401 ccatcctcat caaccccttt tccgcctctt ttacactcgg gaccgggagc cttgccgaaa
    23461 acgccgcaat cagcatcgaa cgcgtgggtc ttgggtttct cctcgcgacg gcgatcgcga
    23521 tacccctcgg cgtcctgatg gggaggtcgc gggccctcaa cgacttcttc gactcgctca
    23581 tcgagatcct ccgccccatc ccgccgcttg cgtgggtccc cctcgccctc gcatggttca
    23641 agataggtct gacatccatc gtgttcatca tcttcatcgg cgctttcttc ccgatcctcc
    23701 tcaacaccat cgacggggtg aagggtgtca agaagacatg gatcgaggtg gcgaccacgc
    23761 tcggggcaag cgagcgccag gtcctcctca aggtcgtcct gccgggtgca gccccgaccg
    23821 tgtggacagg gctccgggtg ggttttggta tcgcctggat gtgcgttgtc gcagccgagt
    23881 ggctcccggg gatatcgcgg ggactggggt acctcatcct ctatgcctac aacttcggcc
    23941 agaccaacct catcatcgcc gggatggtcg tgatcgggct catcgggctt gctatcgacc
    24001 tggtcttcaa gaaggtcgag aagaaatggt tctcgtggcg ggggctcgag cgatgacggc
    24061 acatgcatgt gcaggaggtc gcttttaacg atggcactcg tactcgacag catctcgaaa
    24121 tcgttctccc ttgccgatgg ttcgaccgtg gatgccctct ccggcatctc gcttgcggtc
    24181 gcggacagcg agttcgtctc ggtcctcggt ccgtcggggt gcgggaagac gacgctgctc
    24241 cggatcatcg cagggctcga gaccccgacg agcgggacga tcaccctcga tggcgagagg
    24301 atcgcggggc cgagcccgcg gatggcgatg atattccagg agtactcgct ctacccgtgg
    24361 cggaccgtca tcgacaacat cgagttcggg ctcgagatcc gcgggatgac ccgggaagag
    24421 aggaagaaga gggcaattga gtacctcgac ctcgtgggcc tccgggactt tgccgggagg
    24481 ttcccgtacg agctctccgg ggggatgcgc cagcgtgtcg ccgtcgcccg ggcgctcgcc
    24541 atcgatcctg ccatcctcct catggacgaa ccgttcggcg cactcgatgc ccagacccgc
    24601 aacaggctcc agcgcgagct gctcgatatc tgggaaaaga cacgaaagac cgtgctcttc
    24661 gtcacccaca gcgtcgacga ggccgtgtac ctctccgaca ggatcgtggt cctgacgccc
    24721 cggcccgggc gaatcaggga gatcgtgccg atcgggcttc cgcgcccgcg ggagaggacc
    24781 gacgttgaat tcgcacgtat ccgccgctat gtcctcgacc atgtcgaaaa catggcagcc
    24841 acccggtaag gtttaatagc ggcggtctcc attttataaa gcacagacag ggaccaggag
    24901 acaggaaaaa tggtacgaaa accaggaaag atgtaccgga acctcgcaaa gaaggcatac
    24961 acgcgcaagg aatacatggg aggcattccg ggcagcaagg tcgtccagtt cgacatgggg
    25021 aacctgacag acgagttccc ggtgcagctc tccctcgcag tggaagaggg ctgccagatc
    25081 aggcacacgg cactcgaggc tgcacgtatc agcatcaaca ggcgcttaat caaggacgtc
    25141 gggaggatga actaccgtct caagctccgc gtctatcccc accacgtgct ccgcgagaac
    25201 aagcaggcaa cgggtgcggg cgcggaccgt gtctccgagg ggatgcgcct tgccttcggg
    25261 aaggcagtcg ggacggcggc acgggtcatg ccgggccagg aagtcttctc ggtctacacg
    25321 acaccgcagt tcctggacaa ggcaaaggag gcactccgct cgggaagcca caagctcccg
    25381 tcgccaaccc ggatcatcat ccgggagttg cctgtttcaa aggcccctgc agcagaacag
    25441 gcataatact cctttttttt caaggccgtt ttcaaaggat cagctgtccc tttttccggg
    25501 caaccgggga ctcaatcgtg cgtcccggga gatctttccc ctcggcaggc aactgtacct
    25561 tttccctccg ggacgggaga agaaggcatc cggaaaccgg gcaaaaatca cttccagccg
    25621 caaactgctc caatcctccg cccgggtgca tgacgggaca gcggtttttc ccaaaaaccc
    25681 ctatcacaat gtatattcct ttttatcgac acaattattg caatatgatc ccttccccgg
    25741 acgatgcgct ctgtgcagcc ctgacccgtg ccacctgcag ggcactcgag caggcagaga
    25801 tcttccttcc cccggacgtt gtccgggcac tggaagcggc acgggacagg gagacgagcg
    25861 ggattgcccg cggggagata gaaaacatcc tctccaacat ccggatggcc gaatccctcc
    25921 gggtccccat ctgccaggat acaggtgtcc cggtcatcta cctgacgctc cctcccggaa
    25981 tccccctctc gggcacgctc cttgatgcag ttgccgaagg cgtccggctc gcgacgcgga
    26041 caatccccct gcgccccaac gtcgtcgatc ccctcacccg gaagaacacc ggggacaata
    26101 ccgggccggg catgcccgcc gtccacgtca ggcacgggga gagattgacc gtaaccgccc
    26161 tcccgaaggg ggccggcgcc gagaacatgt cacgcgttgc catgatgctc ccgaccgaca
    26221 cgggaaatgt cgcccggttc gtggccgaga ccatgctcat tgccggggga aaaccgtgcc
    26281 cgccggtcgt cctcggcgtt ggcatcgggg gaacgttcga cggggccgcg gcagcagcga
    26341 aggaggcact cctcgacccc atcgatacca tgacggagta cgagcgcggg ctcctggacg
    26401 ccgtcaacga cctctgcatc gggcccatgg gccttggagg aaagacgacg gcactcgccg
    26461 tcaaggtgaa gggtgccggg tgccacacgg cctccctccc ggtcgccgtg aacgtccagt
    26521 gctgggcgtg caggagggca acggtggagg tggagtggtg acgcggatag acctctccac
    26581 ccccctctcc cacgaggtcc tgatgctgcg ggcaggcgac cacgtcacgc tctccgggac
    26641 cgtctacacc gcccgcgacg aggcacacct ccggatgcgg gaggagggca tccccttcga
    26701 cccgcacggg gctgccatct accactgcgg ccccgtcatc cacgagggaa ggattattgc
    26761 cgcgggcccc acgacctcgg cacgcatgaa cgcgctctcg ggattcctcc tcgagcaggg
    26821 tgtccgggcc ctgatcggga aagggggcat gagccggcag gtcgcggacc agatgaaggg
    26881 ccgggcggta tacctcgcgt tcacgggcgg gtgtgcggcg ctcgctgcgt cccggatgac
    26941 actccgccgc gtctttttcg aggatctcgg gatggccgag gccgtgtacg agattgatct
    27001 cgaccacctc ccgctcgtcg tcggtatcga tgcggccgga aacgacctct tcgagggagt
    27061 gaacaggaac gcccaggcca ggttcaagaa gaggttttcc ctctcccggg aggccgtgcc
    27121 atgaaactgg tcatcgacga gaagcgctgc aagggctgca acctctgcac gatggtctgc
    27181 ccctacaaaa tctacaagcc cggaaagaag cccaacgaga ggggtatcgt cgtgcccgaa
    27241 ctcgacaggc ccgaacggtg cccgaactgc cgcctgcagg cgctctacgg gaggaccctg
    27301 tgcggcatgt gccagatgat ctgccctgac caggccatct catgggtcga ggaaaaaccc
    27361 ggggagaaga agaaggtggc gatagagttt tgacacggat cgagttcatg caggggaacg
    27421 ttgcctgtgc agaaggggca ctggcagcag ggtgcagttt ctttgccggg tatcccatca
    27481 cgccgtcgac cgagatcgcc gagcacatgg ccgcccgact cccgaagaag gggggcgtct
    27541 tcatccagat ggaggacgaa ctggcaagca ttgcagccgt gatcggggcc gcatggaccg
    27601 gcgcccgcgc aatgaccgcg accagcgggc cggggttctc cctcatgatg gaaaacatcg
    27661 ggtttgccgc gatgaccgag accccctgcg tcatcgtgaa catccagcgg ggcgggccct
    27721 ccaccgggca gcccacgatg tcggcccagg ctgacatgat gcagtgccgg ttcgggtccc
    27781 acggtgacta cagcatcatc gccctctccc cggcaagcgt ccaggagatg tacgaactct
    27841 ctgccgaggc cttcaacctt gccgaccggt tccgggtccc ggtgttcctc atggccgacg
    27901 agatcatcgg gcacctgcgc gaaaggatcg agatccctga ctctgtccaa aagacagaga
    27961 gaaaaccgct tccgccggga gaactgccgt tccacccggg cgatgacctc gtccccggct
    28021 tcccccggtt cggtgccggc cacggcgtcc acgtgacggg gctgacccac gacgagcggg
    28081 gatacccctg tgccacgaac ccgaaggtcc acgaggaact ggtcaggagg ctcgtcgaga
    28141 aggtcgagtc aaaaaggcac gagatcgccg actacagggt cacgaacccg gatgccgagc
    28201 tcgtctttgt cacctacggg tcacccgcac gctccgtgga gcaggttctc cacgacaacc
    28261 cggagaagac gatcgggcac ctccgcttca ggatcgtgtg gcctttcccc gagaacgcac
    28321 tccgggaatt ccccaacgcc cgggctttcc tcgtccccga acagaacctc gggcagatgg
    28381 cacgcgaaat cgagaggcac acgacagtcc cggtcatccg gctgccgcgg tttggcggcg
    28441 ccctccacac gcccgaagaa ctggtcgcag cgctggaggg actggcgtga cctacaccga
    28501 ctggctccgg gccgaccggc tcccccacat ttactgcgca gggtgcggaa acgggaccgt
    28561 gatcaactgc acgctgaacg ccgtcgtgca ggcgggcttg aagaaggagg agaccgtctt
    28621 tgtctcgggt atcgggtgtt cctcccgggc ccccgggtac atcgtgaccg attccctcca
    28681 cacgacgcac gggcgggccc ttgcattcgc aaccggcatc aagatggcaa atcccgccct
    28741 ttccgtcata gtcttcacgg gcgacggcga cctcgccgcg atcgggggga accacttcat
    28801 ccacgcgtgc cggaggaaca tcgatctcac cgtcgtctgc atgaacaaca tgatctacgg
    28861 gatgaccggg ggacagggaa gtccgaccac gccccggatg gccctctcga cgacgacgcc
    28921 gtacgggtct gccgaacccg cattcgacct ctgcgaactt gcgattgctg ccggtgccaa
    28981 ttacgtctcg cggtggacat cgtaccacgt gaaagaactg acgcgggcga tcctcgccgg
    29041 gctgcggacg ccgggactct ccttcatcga ggcgatggtc cagtgcccga cgaactttgg
    29101 caggcgcaac cggtaccgcc agcccctcga ccaggtcgaa tacttcaagg cgcacgggat
    29161 gctggttgaa aaagtccgcc ggatgcagga ggagggccgg gagatcccgc cggatacaat
    29221 cgtgctcggc gagcttgccc ggcggaaccg gccggccatg ggggtaaagc catgaggcac
    29281 gaggtcaggt tctcgggttt cgggggccag ggtatcatcc tctcggccgt gatcctcggg
    29341 agggctgccg tgatgtacga cgggaactat gccgtgcaga cccaggtcta cggcccggag
    29401 gcacgcggcg gcgcctcgat gagctcggtg atcatcgatg acgctcccat cctctacccc
    29461 aaggtcaggg accctgacat cctcgtgatc atgtcgcagg agggtttcga gaagtacggc
    29521 gccaatgcag ccgaaagcgc gttcatgatc ctcgactcct ccctcgtccg gtcccgtccc
    29581 cggtgccggt acctcgggat accggcaacg accgaggcaa agaacactct cgggagggag
    29641 atcgtcgcaa acatcgtgat gctcggggca ctcgtccggg caacggggat cgtgcgggag
    29701 gagtcactcg agaaggcaat cctcgacagc gtcccgaagg ggaccgaatc actcaacgtc
    29761 agggcaatga aacgcggaat ggaacttgca tcaggggaga agggacaatg aagctcctgg
    29821 aacacgaggc acgaaagata ttcgcagagc atggcatccc ggtgccggcg ggatccgtca
    29881 tcaggtcgcc cggggaactt gccacagtca tggacacgct cggggaccgg atcgtcctga
    29941 aagcacaggt cgaggtcggc gggcgcggaa agaagggcgg ggtgctcgtc gccgaccggt
    30001 cgaacgcgca ggaactcgca tcgagactct tttcaatgga gatcggggga atacccgtca
    30061 gggaagtcct ggccgtcgag tacctggaca tccggcacga gtattacctc tccatctcgg
    30121 tcgaccgctc caggaaatgc gccctcatcc tcttttcaga ccagggcggc gtcgacatcg
    30181 aatcgcttgc ccgcgatcgc ccggacgcgc tccgccgggc tgccatcccc gtcctgatgg
    30241 accgcgtgcc ccccttcatg atccgcgacc tcctgtcggg ggcgcctgca gagatagggg
    30301 acgtcatcaa caggctctac tcggtattct gcaggaaaga cgccctcctc gcagagatta
    30361 accccctcgt catgacgcca gccgggctct atgcggccga tgcaaagctc gtgatcgatg
    30421 acaacgccct ccggcggcag gggatcgccc agaaccgtga cctgaccgag agggagaggg
    30481 aggccgagaa gcacgggttc tcctacgtcg agctgaaagg cgacatcggt gtcatcggca
    30541 acggtgcagg cctgaccatg gccacgctcg acctcatcca gtactacgac gggtcggctg
    30601 caaacttcct cgacgtcgga gggggcgccg accaggagag ggtgatgcat gccgtcaggc
    30661 tggtcgcggc cgacccctcg gtcagggtga tcgtcgtcaa cctcctcggg ggcatcaccc
    30721 ggtgcgacga ggtcgcacgg ggaatcatcg cggccggcgt ctcccagccc gtcatcgtcc
    30781 ggcttgcagg cacgaacgag aaagaggggc gcgagatcct gcgttcctcg ggataccaga
    30841 tgctcgacag catggaagag gcagtcaggg ctgcagtgga ggcgacacga tgatctacgc
    30901 tgacaaggac tgcggcgtga tcgtgacggg ggcgaccggg aaacagggcg tcttccacat
    30961 cagcctcatg aacagctacg cccgcgaggt ggggggacgg ggcgtcgtcg ccggtgtcac
    31021 ccccgggaaa gggggtcagg aggtcgccgg tgtcccggtc tacaacagca tcagggaggc
    31081 gctgcgcgag cacgacgcta ccgtgagcgt cattttcgtt cccgccgctg ctgctgccga
    31141 ttccatcatg gagtcggcga gtgcgggaat gtcccttgcg gtagccatca ccgagcacat
    31201 ccccgtccac gacaccatga aggccatcgc ctttgcacac ctccacgact gtgccgtcat
    31261 cgggcccaac tgccccggtc tcctctcccc gggcgcaatc aagctcggga tcatgcccgt
    31321 ccacctctcc atgcgcggcc acgtgggagt catctcccgg agcggcacgc tcacctacga
    31381 gatcgtggac cagctgacgc gggcgggcct cgggcagagc accatcgtcg ggatcggggg
    31441 tgacccagtc atcgggcaga cgtttaccga tgtcctccgc cggttcgagg aggacgacca
    31501 gacaagggca gtcgtcatca tcggggaggt cggcggctcg ctcgaggagg aaggggcgaa
    31561 gtcaaccgac ctcccggttg ccgcctacat cgccggcgtc tcggccccgc ccgagaaacg
    31621 gatgggtcac gccggggcaa tcatcgaggg gggagagggc gatgcccggt cgaagatcga
    31681 gcggttgcag aagatgggcg tcccggttgc acggcggcca tccgagatcc cccggctgat
    31741 ccgggaactc ctctgatacc gcggacccgg ggtcagggtc ccccgccccc ctttttaaaa
    31801 aaaccattta acctcctggt taccaccaca tgtgtaccta actgatggga ggaacgatga
    31861 ccgaatacca gacaggagag ggtgacccgt tcggggagga cgaggtactg accgggccgg
    31921 cacgctactt aagacccggc gaggaactgc tcgtctatac acccgggatc cagatcaaga
    31981 agttccggtt cgacgcatac ctgacagata cgaggctctt tctcacggat ccgggagaga
    32041 aggccgccgg ggtgacggcc aaggagattc cccgcgagtc gatcatcgac agctacatcg
    32101 aacactcccc cgcacaggaa cccattctcg tcctctcgat ccggaccggt gaagacgatg
    32161 tccggaccat gaagatgaca tttgtccaca cgggaaaaga cagggtcagc gaagccgagg
    32221 agtggatgca cctcatcaaa cacggcgggc ctgtaccggg ggccgcggca gcacctgccg
    32281 ccgggatcac gaaagagcct gcacccccgc tctcgcccga ggcacgcgca ctctcggaga
    32341 cgatggtctt tcctccacct ccgccaccac aacgggacat cccccctgcc ccgcggcagg
    32401 cacctgcccg ggaaaggtcc gcgtccgtcc cgccacctcc cccgcctcgc ccgccggcac
    32461 agtccgccgg gtccacgacg cagatccagt tctgttacca ttgcgggcac cggatcccgc
    32521 cggtagcaaa cttctgcccg tactgcggga cccgcatggt aaccccggcg gggcacgggg
    32581 gatcacctgc tcccctcgca ccgcgggcgg gtgcccctgc agagcctgta ccggagaaaa
    32641 aggagaagaa agggagaatc tggaacatct tccggcggaa gaaatccgaa ccctgaccct
    32701 cttttcaccc tgccctcact tttcaaaaac cgcgtgccgc ccgcttcccg gctccccttg
    32761 tcccgcgcga ctgtcccgga gcgtatttac tcggaaagga atgattatga gtcttcccgt
    32821 catttttata ctggttacgc atccggttac cgagggatac aattgaagag aaatatcagg
    32881 gtcgaggaac tgcaccagat cccgctggaa cgccaggaga tcgaactcgt cgagagaaaa
    32941 tgcctgggtc accccgacag tctcgcagac ggcattgccg agtccatcag cagggcgctc
    33001 tcccttgcat acctcgagga gtgcggtgcc atcctgcacc acaacacgga ccagggagag
    33061 atcgtggcag gggagtccca gccgaagtac gggggaggca aagtcatccg ccccatctac
    33121 atcctcatcg acgggagggc caccaagcag ttcaacggga tcagcatccc gacagatgcc
    33181 atcgccgtcg aggcagcacg caattacctg cgcaaaaccc tgacaaacct caacctcgag
    33241 cgggacgtca tcgtcgactg ccggctcggc accgggtcca ccgacctccg cgaggtcttc
    33301 aagccgtgcc agaacacccc cccgcgggcc aacgatacct cctttggtgt gggccacgcc
    33361 ccgttctccg agaccgagac gatcatcctt gccgtcagtg actacatcga ccagacgctc
    33421 cggccaaaat accctgttat cgggcaggac atcaagatca tggggctccg ggaaggaaac
    33481 acgatcaccc tcacccttgc ctgtgccatg gtcgacaaat actgtgcggg gcttgccgag
    33541 tacatcgagt tcaaggacaa gatacaggaa gaggccctcg ccgtggcaag gaagtacacg
    33601 ccgcgcaagg tccgcgtggc agtcaacacc gccgacgata tcgacagcgg cagcgtttac
    33661 ctgaccgtca ccgggacttc tgccgagatg ggagacgacg ggtcggtcgg ccgcggtaac
    33721 cggtgcaacg gcctgatcac cccgaaccgc cccatgagca tggaagccac gagcggcaag
    33781 aacccgatca accacatcgg caagatctac aacatcctct cgacgcagct tgcccaggag
    33841 tgcgtccggt ccgtcgacgg catcgaggag atctacatcc ggctcctctc ccagatcgga
    33901 aagccaatcg accagccgct ggtcgcaagc gtccaggtcc tgcccaagcc cgagttcgag
    33961 ctgaaggcga tcaggcccga tatcgaggca atcatcgatc acgggcttgc cgaggtcacc
    34021 tgcatcacag agaagatcat ccgtggcgag atcaagacgt tctgagccgg gcaggaaacc
    34081 cccggtcccg gccggcggcc ccctcgtccg cctggccatc ccgaacaagg gacggatatc
    34141 agcccccgtc ctcgagctcc tcgaaaagag cgggctccac ctcgacgagg gcccggaacg
    34201 gcgtctcgtc gcccgcacgc ccgatccgca ggtcgaagtc ctcttcgcac gccccgtgga
    34261 catcccggag tacgtcaacc tcggggctgc cgaccttggg atcacggggc acgacatggt
    34321 caccgagcgg cgtgcggatg ttgccgaact cctcgacctg ggctttggaa gcgcaaacct
    34381 cgtcctcgcc gtccgggaag agtccccgtt ttactcttcc cgcgatcttg cgggcgcccg
    34441 cgtggcaacc gagttccctg tcattgccgg ggactacttc gaaaagaagg atatccccgt
    34501 caccctcgtc cccgtcggcg gggcctgcga ggcaaccccg tacctcggca tcgcggatgc
    34561 aatcgtcgac ctctcgagtt cgggaaatac gcttcgttcc aaccgcctga gagtcatcga
    34621 ccacgtgctt gcgacgagca ccgtcctgat cgcaaaccgc cgttccctgg agacgaagaa
    34681 gaccaagata gaggagatct gtgtcgcgct cgagagcgtg atccgggcca ggggccagtg
    34741 ctacctcatg atgaacgccc cgagatccca cgttgccgag atctcctcca tcctgccggg
    34801 actctcgggc ccgaccgtga tggaggttgc atcgagagag gacatggtcg ccatccatgc
    34861 cgttgtcgcc gaagaaaggg tctaccagct catccacctc ctcaagaggg ccggtgcccg
    34921 cgacatcctc gtgatgtcga tcgagaggat gatcccctga tatgcgcgtc tttcctgctg
    34981 tcgatatcct gggcggaaac tgcgtccagc tcgtgcaggg gaggcgcgag tctgcaacgg
    35041 tcttcgggga cccgctggcc tgtgcccaaa agtggctttc ccgtggcgca gactgcctcc
    35101 acgtcgtgaa cctcgacggg gcattcggcc ggtcgcagga aaacgtccac catatccgga
    35161 agatcatccg ggagaccggc gtcgaggtcc agctcggggg cgggatacgc tcgttcgaag
    35221 atgcggcatc gtggctcgat ctgggcgtct tccgcgtcat cctcggcaca ctcgcaacga
    35281 aggaccctgc agtcctcggg aaactttccc gggagtatgg cagggaccgg gtgatggcag
    35341 gcctcgatgc ccggcagggc caggtcacgg tcgagggctg gcagaagagt gccggtgact
    35401 acctcgactg ggcggtgcgg ttcgaggaat gcggtgcagg gtctctcctc ttcacgaacg
    35461 tcgacgtgga aggtctcgag aagggtatcg acccccggcc ggtcggggcc ctcctgaaga
    35521 ggacacgcct ccccgtcacc gtggcgggag gtataacaac gatcagcgat atacgtctct
    35581 taaaggatct cggggcgcac gccgttgtcc tgggatcggc cctgtacagc gggaagctgg
    35641 acctggcgca ggcaatggag gctgcacgat gaggagagca gaggtgattc gggagacgaa
    35701 cgagacacgc atagcgctcg agctcgacct ggacgacccc ggcagcgggg agatcgcgac
    35761 cggtattgcg ttttttgacc acatgctggc ctcgatggcc cgtcacgggc actttttcct
    35821 ctcctgccgg gccgagggtg acctcgatgt tgacgcccac cacacgatcg aggacacggg
    35881 catcgtgctc gggcaggcgt tccggcaggc gatcggggac gggaagggga tcgtccggtt
    35941 cgcccatgcc ctcatcccca tggacgaggc gctcgcctgt gctgcccttg actgcggggg
    36001 gaggggctac ctcgtcttca agggcgaatt ttcccaccag aaggtcggcg gcgtggaaag
    36061 ggagatattc gagcatttct tctacagcgt ctgcatccgc ggggggatca ccgcgaacct
    36121 ctccatggag ggaaaaaacg accaccacaa gtgcgaggcc cttttcaagg cgttcggtat
    36181 cgccctcggg caggcgacgc ggaccgggcc ctggccacaa acgatcccga gcacgaaggg
    36241 ctcgctgtaa cggcgtgaaa aaccagcccg gaaccctgcc gggcacgggg atgtgccgga
    36301 catatttttc gctctttttc ccttttttgt gcccggaaca ggatcacatt tatcccctcc
    36361 cgttaccatc ccacccatca tgccatgctt tatcattctt ggaaaactga gcgagagggc
    36421 cctggggaga atgaaggagg caaaggaccg ggacacccag atcaaaaaag tcatcgggga
    36481 tgccggggga acgcttgtct cccactacta caccatcggc cgctacgatg tcgtgatgac
    36541 gatcaatctg cccaacgagg agatactcgc aaaggtgctt atcggcattg gaaaattcgg
    36601 aacggtcagc acggaaacga tgactgccct cctgccggaa cagatgtacc ggatggcaac
    36661 cgggacgtga ggggtcttt
//
LOCUS       DAOOJU010000017        34337 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1380_length_34337_cov_15.417858, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000017 DAOOJU010000000
VERSION     DAOOJU010000017.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 34337)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34337)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34337
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1380_length_34337_cov_15.417858"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            163..783
                     /locus_tag="PK679_05670"
     CDS             163..783
                     /locus_tag="PK679_05670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55481.1"
                     /translation="MVLKRTLAWVRMPPLSKKEKGQYLPAPYSFSYVSGIPRVPVEGE
                     VFSVNEILIFGVIIGGIFSAIGSAVLVHMGELIDRFPVEGEGERERSMWSPREFTRYA
                     VIFYWPLYIVGAAMMIPGTRVLTVGGIAIIFGLVLFMLTALVFSVATYNLMQSGREKS
                     TKQRFLGSFFGTRNLFRVSPYRAGSFRSRKKEKDSGNDKDTREKQD"
     gene            complement(828..2042)
                     /locus_tag="PK679_05675"
     CDS             complement(828..2042)
                     /locus_tag="PK679_05675"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HPC55482.1"
                     /translation="MPIGTLKDIRPENKTLLLRLDLNSPIDPATHHILDDKRFREHLP
                     TIQALSGSRVVIITHQSRPGKKDFTTLEGHAERLEGLLQRKVRYIDDIFGQCARDAVR
                     RMKNGDVLMLENVRFNAEENLKLKPEEASKTHLVQKLSQMGDIFVNDAFGTSHRSQPT
                     MVGLPMVMRSVAGLLMEKEVTTLSRVFENAPGPVCMVLGGTKVDDSLSVAEYVLPNNV
                     ADLVIVTGVVANVFLRAAGFRIGRGSDQIIQQLGYEKEVERARLLLDSYRDRIMYPGS
                     VAVKEGGRRVEYPADSIPGDAMILDAGMDAISCLAERIRSSRTVVFNGPAGVFEDPDY
                     ATGTHELLRAASKVEFSIIGGGHTAAVVEKMGIDKDFSHISTGGGACIEFLTGKKLPA
                     VDALERSRALFG"
     gene            complement(2061..2687)
                     /locus_tag="PK679_05680"
     CDS             complement(2061..2687)
                     /locus_tag="PK679_05680"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HPC55483.1"
                     /translation="MALRDIKPTRSELINLKKKIALSERGYKILKMKRDGLILEFFKV
                     LEQAKDTRGDLMEKYERARELMAVANTVEGAIGVKAAAFSVQEVPAITVASKNIMGVV
                     VPEIDASKVKKGLMERGYGILGTTPVIDETALAFEELVEAIIRSAEVETTMKRLLDEI
                     ESTKRRVNALEFKVIPEMTAARDFIKMRLDEMEREELFRLKKIKARTT"
     gene            complement(2694..4085)
                     /locus_tag="PK679_05685"
     CDS             complement(2694..4085)
                     /locus_tag="PK679_05685"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016469 - proton-transporting two-sector
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit B"
                     /protein_id="HPC55484.1"
                     /translation="MKEYRTITQIAGPLVFVEKTEPVGYGELVNIVLYDGSIKRGQVL
                     DTSDELVVVQVFETTAGIGRDSGIRFTGETIKMPVGRDMLGRILSGGGKPIDGGPEIV
                     PEKRLDITGAAINPYARGSPNDFIQTGISTIDGTNTLVRGQKLPIFSGAGLPHNQIAL
                     QIARQAKVPGSKEAFAVVFAAMGITKEEANYFMQDFERTGALERAVVFLNLADDPAVE
                     RIITPRLALTTAEYLAFDLGMHVLVILTDMTNYCEALRQIGAAREEVPGRRGYPGYMY
                     TDLAGIYERAGIVKGKKGSITQFPILTMPGDDITHPIPDLTGYITEGQIVVSRELHRK
                     GIYPPINVLPSLSRLMNLGIGKGHTREDHKKVSDQLYAAYAEGNDLRGLVAIVGKDAL
                     SERDRMFLEFADLFENRFVRQGYTEDRTIEETLDLGWNLLSTLPVEQLVRIDRDLINK
                     YHPKFRQTAKAEG"
     gene            complement(4082..5848)
                     /locus_tag="PK679_05690"
     CDS             complement(4082..5848)
                     /locus_tag="PK679_05690"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016469 - proton-transporting two-sector
                     ATPase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit A"
                     /protein_id="HPC55485.1"
                     /translation="MEVKAQDTKTTKTGVLKRIAGPVVTAVGIEAHMYDVVKVGKEEL
                     MGEVIKIQGENIIIQVYEDTSGIRPGEPVINTGLSLAVELGPGLLTSIYDGIQRPLSV
                     LVDKMGDFIQRGVSAPGLDHSKKWEFRPLVKEGQEVGPGTVIGEVQETNIVHRILVPP
                     NVKGGTVKSIRSGSFTVDEVICTLDDGTSLTMMQKWPVRVPRPVLEKMNPTVPLITGQ
                     RILDGLFPIAKGGTAAIPGPFGSGKTVTQQQLAKWSDAEIVVYIGCGERGNEMTEVLT
                     EFPELEDPKTGKPLMERTVLIANTSNMPVAAREASVYTGITIAEYFRDMGYDVSLMAD
                     STSRWAEAMREISSRLEEMPGEEGYPAYLAARLSEFYERAGRVRTLGGKMGSVSVIGA
                     VSPPGGDFSEPVTQNTLRIVKVFWALDAKLSQRRHFPAINWLNSYSLYLDSLQEWYDR
                     EVSPEWNSLRSWAMEILQKEAELQEIVQLVGSDALPEAEQITIEVARMIREIFLQQNA
                     YDAVDTFCDMKKQYDMMKAIRQYSDLAYAAQNAGVTPQQILSVRSKNELPQIKFIKDY
                     VPALAKIQADMESEFNALRSAA"
     gene            complement(5839..6141)
                     /locus_tag="PK679_05695"
     CDS             complement(5839..6141)
                     /locus_tag="PK679_05695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HPC55486.1"
                     /translation="MEIAVIGNQEFILGFRLAGIRKTYPAESDEKLVEYINRVLDDPE
                     VGILVLQSGDIRKIPRRLQMTLEESVKPTVITIGAEEGGLSMRERIKRSVGVDLWK"
     gene            complement(6141..7196)
                     /locus_tag="PK679_05700"
     CDS             complement(6141..7196)
                     /locus_tag="PK679_05700"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HPC55487.1"
                     /translation="MAEIRAGPVPYIYVCTRMRVRKSKLLPREEYMRMLNMGLAEITR
                     FVGESQYKREVDELATSFRGIDLIETALSWNLAKEYQNIQKITPGTLKDLTRAYLRRW
                     DIQNVLTIIRGKLHGEKKGKIREVLVPAGELDRVFLDRLLEEPTPERVIEALKGKGIY
                     PILSRMTEGGVREEILPKVENELYKQFYADLIAYAHSGIKGGRQFLDYITLDIDITNI
                     RTLFRVRADPSVSDISGVLIAGGTISPQALQRVFQIKDTNEFIDALVPLIKVRPLREL
                     LEKLREERSLREIEIELIKVQLAEMETMSKLHPFSIHPILAYLEMKKYEIFNLRALAR
                     GKESGLAPERIRGYLVV"
     gene            complement(7209..7787)
                     /locus_tag="PK679_05705"
     CDS             complement(7209..7787)
                     /locus_tag="PK679_05705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033178 - proton-transporting two-sector
                     ATPase complex, catalytic domain [Evidence IEA];
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E family protein"
                     /protein_id="HPC55488.1"
                     /translation="MGLEAVLEEIRERGRKEVERIRRESQEETTRVLSAAQERAAKIK
                     QAANEEVERQAAYVMNQEASAANLQVKRELLNTQKELLDQVYLRAKELIAGLPESFHR
                     EAITNLLKEAKTQIGEGVVHVNPRDRKVLEQVLAQNPEFKSFSVGSDANIDGGVIVER
                     KDGSLQLDYSYHTFLDMVWESGLKDASDLLFG"
     gene            complement(7798..8064)
                     /locus_tag="PK679_05710"
     CDS             complement(7798..8064)
                     /locus_tag="PK679_05710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HPC55489.1"
                     /translation="MAEAAAVAATEMTVEMVKASQLGMKALGAGLAVGLTGIGTGLAE
                     MAIGSAAVGATAENKDIFGLVLLLTVIPETIVIFGLVVGLLLLF"
     gene            complement(8066..10039)
                     /locus_tag="PK679_05715"
     CDS             complement(8066..10039)
                     /locus_tag="PK679_05715"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HPC55490.1"
                     /translation="MFTPEGMTRVLIAATKSQMEPVIRELYRQHLFHIEEFVEKDSKE
                     YEGYRIGTPLPAANETSRELIRLRGITSSFGIREDEEVPVSQKVKSSHLREVIEKELP
                     LLEQETEELLAKRAKLDAQIKEYEQKIETLRPFQDVPFDLSLLRGFRMFSVYCGYISK
                     SLSLDVPHEIFSADTKKGKFVIIVVQQKDRAGVDQALPEAQFQAVPIPDEDGLARDRI
                     GFYESQILARKGEMEEINRKLDDIRTRHRDLFLACHELLSADVEMAEAPLRFATTGRS
                     FVVEGWVPTVHLERLKEGIHYATGGKVFVYECEPSEISDVPPTEYHNPGFAKPTEMLM
                     DVYSRPRYTELDPTLIVSIIFPIFFGIILGDVGYGAVLLVLSLALHRFLKGEEARRLA
                     IILRNASISSIIFGILFSEIFGFSLPWKPLLFSRHLNIGGHAGGHGPDVTGLMIMAVW
                     IGILQITLGRVLGMVNHARQDHGSHRVKAVLANLGWIMVLWGILLMIWASFSMPFMPD
                     LTGMPPIGMGLNLASIGGLVMIVAGVLFIILDSPLEVVELPTILSHVLSYARLVGVGL
                     SSVAIAMVVNFIAIGLIIEPQLESLTALGVIFIIIGGIVLVVGHLLNTILGMLGGALQ
                     SLRLQYVEFFTKFYKGGGRKYNPFGMKKRFMED"
     gene            complement(10026..10355)
                     /locus_tag="PK679_05720"
     CDS             complement(10026..10355)
                     /locus_tag="PK679_05720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HPC55491.1"
                     /translation="MKTEVLQKIKLTESEYEKMISEAVAEAKRTSAHAELEADNLIMK
                     ATHDAEEYKKARMAEIRENAARRREEILKDGRARAAELRQRGSRNLEKAASLLVSRFR
                     ERLHVHS"
     gene            complement(10487..11038)
                     /locus_tag="PK679_05725"
     CDS             complement(10487..11038)
                     /locus_tag="PK679_05725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HPC55492.1"
                     /translation="MYCPVVQPGPDELLLIRGENSFIVAGQAGTRFSLCIETPDDEYC
                     QSVWPHHIIAVSAPEGGSLSAASMLFCLVRDHHLPLLVMRKDHPGSRRLRYVVSAGER
                     ILLSCAIVRGTHPEQDLLCSSAELAGILLEGRESGIRITNCPHSAEVTVIPFPKNRPD
                     KTRDRWPPAGGGRGPDSLPGESG"
     gene            complement(11056..12990)
                     /locus_tag="PK679_05730"
     CDS             complement(11056..12990)
                     /locus_tag="PK679_05730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HPC55493.1"
                     /translation="MSLNSFLRNRVRQNPLKYQKLESDLESARFGVTVERYLARAIQI
                     GVATGIAFALLGFWLTGIIVYTAGGGSYTGVYNVFSIPFPEKIEPQSAYALPLQVTGA
                     IVAFIMGFMIVYLIALHYPSMQKKNRATKINLTLHNAVAYMYAMRKGGAQMMTIFRSL
                     SENAKIYGEVALEFRQVVRDADFFGYDLVTALRHLIRTTPSEKMKQFLEDLVSVIESG
                     GDLVGFLSGRVRLYQEEARFEQKQFLQFLSLVAESYVTLFVAGPLFLIIIMVVMGMMG
                     GMAILQLTAVVYLVFPIGSAVFILLIDLISLKSEVVERFVRAKLLHEYSDVPVYHREG
                     EEPFFSRLARYDRVRRIREFFRHPFEFFVKNYNYTLLFSVPLAVLYLVALFLVVPQYN
                     DIEIYIDVIDDHVMIALLIVLLPYSFFYEMWRRNIEGMEALIPEFLERMAGINQVGLT
                     IAQAISIMVNTNLGLLSYEIRRIKRDIDWGASFADALVRFEDRVRTPLIARTVSLITK
                     ASQMSGSIGDVLAIAASDAKMSDLLKRERLSDMFIYTAIIYMAFVVFVFVVGVISNSF
                     IPILGNVGGGTIPQGTPLASISSSSIKAILRLMYHSVVLQALMSGLIAGQMGEGSLKA
                     GVKHSCIMLVIALVIFNLVL"
     gene            complement(12987..14621)
                     /locus_tag="PK679_05735"
     CDS             complement(12987..14621)
                     /locus_tag="PK679_05735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system ATPase subunit"
                     /protein_id="HPC55494.1"
                     /translation="MVKRLRPVSGGDVVETAPPEFSFTSFLKKKKTSVSFPEYDFKRD
                     GTLVDAEIPPRYSEVERYYVDEGRSLVVIALNEKTNQYEYLLFEPKLSEFEYELLERL
                     HEDMRSALILTDDEIAMDKRTLLLEKMQELLHEYGIKPEDKSIFRIQYYLTRNFIGWG
                     RIDALMKDRNLEDISCDGHRIPLFLYHRKFRNVRTNIMFEPEVLNSLAITLAQRSGKH
                     ISTGTPMLDATLPDGSRLQLTLGTEVTTRGTSFTIRKFREEPFSPVELLQYRTFSVDE
                     LVYFWLAIENQKSLLFVGGTASGKTTSLNAVSFFIPPMAKVVSIEDTREITLFHENWI
                     ASVTREMVSEGANIITMFDLLRAAMRQRPEYILVGEVRGVEAQTLFQAMNTGHTTFST
                     MHAGSVDAAIHRLENEPLNVPRNMITALNIVSVQALIYRGTERVRRSLEIVEIAGIDP
                     STGNLRVNTVFVYDPVHDVFTYKGRSQIYADIAERRGWSREKLEAEIATRKSILLAME
                     KQGIIDYVRASRIFQAYHINPESVTGNLEDLSRVLE"
     gene            14861..15691
                     /locus_tag="PK679_05740"
     CDS             14861..15691
                     /locus_tag="PK679_05740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RAD55 family ATPase"
                     /protein_id="HPC55495.1"
                     /translation="MDDDKAHKTLMPTGIPSLDPVMEGGVPAGSLILLLGDIGAGGPE
                     FAYTSVMLLSRLIHDKPADTETIPREVWYVTFTKGKEDVLSEMTLAFHPDLTRGITDI
                     KFIDLSQIYFDSSIVPLDWYSKKDIFSRLQSRGGHDSILGALATNLGTIPPRSLIVFD
                     SLTDLATQYAKDGIWSDFAAFLRGLQRVAKEWESTVYLILTRGILDNSRELEISDISD
                     AVIFFRWEETTGGRRQRVMYFEKFRGLMPHLEENDLVKFAVRISTNEGFDVSNIRVVI
                     "
     gene            15688..16389
                     /locus_tag="PK679_05745"
     CDS             15688..16389
                     /locus_tag="PK679_05745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KaiC domain-containing protein"
                     /protein_id="HPC55496.1"
                     /translation="MIGGERVRIGIEGLDQMMGGGLIPGSICAIIGTYGTGKTTFGLQ
                     FAWEGLTNGENVIYISLEEREDRLFTYMQDKGWDIAPFSDGRFTVLKLDPSDFNLAIN
                     SIKNELPALVRQMKAKRVVIDPVSLFEDLFDRDSDRRREMFRFIDTLRDQQCTTLMTS
                     ETDKNNPFASRHNHIEYLADTVILLRYVRPSDLTDVHLALEVVKMRLSPHSREIKPYE
                     IQQNQVLVYTEANVF"
     gene            complement(16405..16671)
                     /locus_tag="PK679_05750"
     CDS             complement(16405..16671)
                     /locus_tag="PK679_05750"
                     /inference="COORDINATES: protein motif:HMM:NF019085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pro-sigmaK processing inhibitor BofA family
                     protein"
                     /protein_id="HPC55497.1"
                     /translation="MNLDYTVLAAGVLIAVVLFFVLKDITKLIINSVLGLLTLFLVNL
                     MGFMHVMGRADIPYSLVNVLLCILGGIPGALIVIVLHLIGFEGF"
     gene            complement(16674..18002)
                     /locus_tag="PK679_05755"
     CDS             complement(16674..18002)
                     /locus_tag="PK679_05755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HPC55498.1"
                     /translation="MVRPMFSFGTRWLVAVDTIEKILMAGERQADEVEVYLATGTSVT
                     ARLRKREISYALGSEHQALSLRVIRGGRIGVSSTGNPQAWEACLDAALRSAALAAPQE
                     WDGLPGPAENYGDFVNFDENVVPDPDRVREMVRGMEEGACRYPVEIVSGSAEISQYRI
                     VLANSRGLYREDRESLVSMGLETIREQSTGYEYGTSWKMDIDPGSVGEKAAFLAATSH
                     GGKDIPTGTYDVVLSPDAFGQLMAGSFLPALSGRNVHTGRSRLAHLIGQEVCDPALSF
                     IDDPSNTRGIGSCRWDGEGTPTRTLHLVEKGVLRCFAYDLKTAYQYGCMTTGNAVRSG
                     MGGGIAIGFHCMTLDGPRDEILEKDAIFVHDVVGAHTTNPLTGDFSVELANAYLYRGG
                     NPEYPVRKAMLAGNVFEMLGETGGLSGEEKVVGCCVLPSIRLKNQKIIGN"
     gene            complement(17944..19275)
                     /locus_tag="PK679_05760"
     CDS             complement(17944..19275)
                     /locus_tag="PK679_05760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HPC55499.1"
                     /translation="MAGIRYYDIRHVKGAISHIDIENSRVESAGTTFLDRAVIRVLGP
                     KGWGILTVDRFERPRGKKFEDLLSKASALASLTGEEVTLADAPSGMIPVPPKKTDPLA
                     IDLEEKGRLLLMIEKAARIPGITSTRAGYTERYEDVLFEDSCGNEYTYSLVRSGYSIL
                     AVAGRGGEMQMGYRRRHALQDFPLDNGQKDGETAARRALALLDAKRPRGGTMNVVLDP
                     ELAGVFAHEAVGHASEADLVHEGSSVLRGKIGEQIGSGIVTIVDDPTLPEFGFEPVDA
                     EGSRVERTIIVEKGVLTSYLHSRETLPAVGFGHTGNARAMPGEPPQVRMSNTYIAEGD
                     STTEELIGECREGILLCGSRGGQVDPGRGVFQFNAEYGYLIEHGECRGMVRDVSLSGE
                     ILATLHGIELCAKKRKMHAGYCGKGGQTVPVSDGAPHVLVRDAVVGGSGHD"
     gene            complement(19280..21196)
                     /gene="lonB"
                     /locus_tag="PK679_05765"
     CDS             complement(19280..21196)
                     /gene="lonB"
                     /locus_tag="PK679_05765"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease LonB"
                     /protein_id="HPC55500.1"
                     /translation="MPDQNSTGSVQEDEPPVEVTVEDSSQVQVPPSLIDQVIGQEHAV
                     EVIRKAAIQRRHVMMIGSPGTGKSMLAKAMAELLPKEEMQDILVYPNSDDPNNPIVRT
                     VPAGRGKQIVAAHKAEAKKKIQFRNTLLMLLLIGILGYAFIQGQWLMGILAAAFVFMA
                     LRYATPREESMIPKLIVSNDSTTTAPFIDATGSHAGALLGDVRHDPFQSGGLETPSHD
                     RVEAGAIHRAHKGVLFIDEINTLTPHSQQNLLTALQEGEFPITGQSERSSGAMVRTEP
                     VPCKFIMVAAGNLDAIQGMHPALRSRIRGYGYEVYMSETMPDTPENREKFIRFVAQEV
                     RNDGKIPHFDRSAIEEVIREARRRSNRKGHLTLKLRDMGGLIRVAGDLARQEGAEMTT
                     AEHVIAAKKTARSIEDQVSDEYIRRSREYELTVVEGTRVGRVNGLAVMGSDSGSVLPI
                     MAEVTPAQGASGTVIATGMLKEIAQESIKNVSAILKKFTGKDIKNMDIHIQFIGTYGG
                     VEGDSASISVATAVISAIENIPVRQDIAMTGSLSVRGDVLPVGGVTFKIEAAAKAGIR
                     TVLIPRANLDDVLIEERYRSMVTIIPVDYIDDVLTIALVPDNREGFLNKLRRMATTPS
                     GSFLDGTGIPTSPA"
     gene            21284..22138
                     /locus_tag="PK679_05770"
     CDS             21284..22138
                     /locus_tag="PK679_05770"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HPC55501.1"
                     /translation="MLVVSTEYSQVLAGRIAGALECPLGAVRFTRFPDGEHYLRLERT
                     DPEMVVVGSIPDADALVELLLLVDACEGNEVTLVVPYLGYARQDKKFHEGEPLSARAV
                     CRAISGGVRQVFTVNVHDPSVLSHFRVRAQDISIAGEIGRYLGSRPLENPFILAPDDG
                     ASAFAGTVAATCGWDWDHLEKTRISGEEVRMEPRNLDAAGRDVVIVDDIISTGGTLVT
                     AARMLRAQGAGTVSSACVHGVLAEGAYSRLLASGLSEVACSDTIERACSRFSAGQAIA
                     DRILGCSS"
     gene            22126..23124
                     /gene="rtcA"
                     /locus_tag="PK679_05775"
     CDS             22126..23124
                     /gene="rtcA"
                     /locus_tag="PK679_05775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003963 - RNA-3'-phosphate cyclase
                     activity [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HPC55502.1"
                     /translation="MLVIDGSTLEGGGQLVRSAVTLSAITGQPCRITNIRAGRKEPGL
                     RSQHIAAVRAVAGLCGATVSGCTPGSRELTFCPGPLVEGDMRIEVGTAGSIPLVLQAW
                     LPAALMIGGRITIAGGTEVPMSPTIDYTARVLVPFLRRHGAEISLDVIRRGYYPRGGG
                     EVMASARRSRLAPFSPADTRETDNCGIVSCSAGLPGHVADRQADAASSALFQATGIRF
                     PAWKDTRPGPGTGSSVTAWLGWMAGCAIGRRGYPAENVGRDAAFNLLAEHHAGGLVDR
                     YLADQLLIYCARAGGSFTSSTCTLHARTMCWLLGLFGFRIRVTGGEVVTFAAEESA"
     gene            23102..23563
                     /locus_tag="PK679_05780"
     CDS             23102..23563
                     /locus_tag="PK679_05780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding protein"
                     /protein_id="HPC55503.1"
                     /translation="MPPKRVLDATAFFLDIPLEGELFTTPAVVGEIVDARSKCRLEAL
                     SAAGLVVTSPCASSLQIIGKASSVTGDESVLSRADREVLALALDTGAEVVTDDFAIQN
                     VAHHLGIPVIPLQQRKARKRKWKFRCPGCGRPAEGPGECPVCGSGLKRTLK"
     gene            23585..24205
                     /locus_tag="PK679_05785"
     CDS             23585..24205
                     /locus_tag="PK679_05785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase-like protein"
                     /protein_id="HPC55504.1"
                     /translation="MSSLDELIQKARTLLSEGHSPGQIADELSLSMETVTWLLTQQKG
                     MAVPKDVHIDWTSVSGRGPLLDGVAMMLLKQYYTSLEDEDREGGYSDRFPTLVVGIAV
                     SGIPVATLIAVEEDIKLAIYHPAKHSTQEPPVGSISGNFASVNGERCIIVDDVITSGN
                     TMQDVVKYLRRHGAQPVAICVLFDKRGVRDIDGVPVYSLFKISRID"
     gene            24289..25893
                     /gene="thsA"
                     /locus_tag="PK679_05790"
     CDS             24289..25893
                     /gene="thsA"
                     /locus_tag="PK679_05790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thermosome subunit alpha"
                     /protein_id="HPC55505.1"
                     /translation="MLGGQPIIILKENVERNRGLEAQRSNIAAAKAIASAVRTTLGPR
                     GMDKMLVDQSGDVTITNDGATILQDISVVHPGAKMVIEVAKAQDDEVGDGTTTAVVMV
                     GSLMEKAEAMIEKKIHPTVIAEGYRLGMKKALEVLDDLSIPIDPYDREKLIRIADTAM
                     TGKAIESVKSRLNGIVVDAVMAIATREGDRITADEDNVLIKKQAGDRMDDAELVRGVV
                     IDKKRVSEEMPRKVKDARVALVASPLEIKKTQVKAKIHIKSSDMVSAFTAQERETLKK
                     YADTIIASGANVLLCQKGIADAVAYYLAKGGVLAVEDVPEKDMKFASHALNAQIVNKA
                     EDLTPEALGRAETVEELEDGEFIKISGCHNPKTVTILLRGSTQYLLDELERAVEDGTR
                     VVMDAMEDGKLVVGGGAVETEILMKVRDYAASVGGRAQIAIEAFADAFEVIPVTLAEN
                     SGFNTVDKLVELKNAHARGEKYAGLNVYTGTVVDMLKEGVLEPQRSKRQAIQSATEAA
                     ILLLRVDDMMITREDKKEKEAGKPPE"
     gene            complement(26030..26569)
                     /locus_tag="PK679_05795"
     CDS             complement(26030..26569)
                     /locus_tag="PK679_05795"
                     /inference="COORDINATES: protein motif:HMM:NF033823.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archaemetzincin"
                     /protein_id="HPC55506.1"
                     /translation="MARLPAIGLVGIGNRDQGVIGWVREDLPSLIPAEIRIFHPQILP
                     LQYFDSRRGQYLADGILRSLAEIARRENVLCLGITGSDIFSPGLHFVFGIACTGAALI
                     STFRLRPGFYGMPDNEMVYRRRILTEAVHEIGHALGLAHCEHPGCVMYFSNWIGDTDL
                     KGPEFCYRCRRRVDLLQTG"
     assembly_gap    26775..26874
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<26875..27399)
                     /locus_tag="PK679_05800"
     CDS             complement(<26875..27399)
                     /locus_tag="PK679_05800"
                     /inference="COORDINATES: protein motif:HMM:NF038196.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HPC55507.1"
                     /translation="METILYYFTGTGNSLAVARGLSSVIGDCTLVPIVSEMKKGGPIE
                     PRSDRVGIVNPLYFFGLPSIVAEFAQRLDLSHARYTFSVITMGGTGASAASSQLDHIL
                     KGGPGKRGLDAAFSIRMPGNYILMYDAPDMESLERTLMKSGSRIKEIGEMVKAGKKVF
                     PPWSPVAALVHHLMY"
     gene            complement(27491..27700)
                     /locus_tag="PK679_05805"
     CDS             complement(27491..27700)
                     /locus_tag="PK679_05805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine S protein"
                     /protein_id="HPC55508.1"
                     /translation="MGAKCRFRIIPGHQIVEYTGAEGTTYEEALLSIGIIPDTVLILH
                     GGKSLPQDSVIREEEVDIVSTCSRG"
     gene            27745..27829
                     /locus_tag="PK679_05810"
     tRNA            27745..27829
                     /locus_tag="PK679_05810"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27779..27781,aa:Ser,seq:cga)
     gene            27982..28473
                     /locus_tag="PK679_05815"
     CDS             27982..28473
                     /locus_tag="PK679_05815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55509.1"
                     /translation="MKRSLWILVGITLVLCIWMAGCTQPSQEQTTPAPTTMPVTTAAT
                     SVPMSPTQGPPPTAGYIEGPLPSQYSVDVQVVRNTVAITPNITVSFRGGKGINFVHSM
                     DVVVSRSDGRIVTGSLYKPQVNDYLELEGTRGTDNVEVFINLITGDRYRVYNKPEAFR
                     SYN"
     gene            complement(28687..29391)
                     /locus_tag="PK679_05820"
     CDS             complement(28687..29391)
                     /locus_tag="PK679_05820"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HPC55510.1"
                     /translation="MKISVIIPAYNEAGNIGRCLESLSHQTIPRSEYELIVVDGGSKD
                     ETIAEAEPFCDLVFVQTSRKVGGARNDGIMKAKSPLVATTDADCIIPRNWLEVILEDF
                     SQNPGAVQIYGPVDPIERTFKNHVSLALANTFARVGYYTGTFYYTLGCNTAFRKDAFM
                     RAGMYRCIDAGDDLEIARRMIRFGKIVFDSRMRVGFSMRRYEKFGTLKSLYEWISIVA
                     RGGSSEKYQYSRREYK"
     gene            complement(29388..30362)
                     /locus_tag="PK679_05825"
     CDS             complement(29388..30362)
                     /locus_tag="PK679_05825"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HPC55511.1"
                     /translation="MKVNFYVEDLLFFRYIGCSTVAKTLYNSMKGIPGLEVTWKKYGN
                     HADIVHFHTFGPLADLNRRLSRGKTVLTAHSTPRVNMDNIALARAVNKRYPHIYRRFD
                     HIITISRPCHEEVTAMVPDMPVTMIPNGVDREFFQKDEEKGAAFREDYNIPEDSRVVL
                     TVAQQTPRKGLYDFLALSRACPDSTFVWIGGFPYGALSKDYHKIKRLKLQCGRNVIFP
                     GHINDIIKPYSAADVFFMPSYAETFGLVILEALSCGLPVIAREIPEFRDIYGDSILYF
                     SERSEVPALLEDERSLGRCARGAREFSARFDIRDIAEKHVRLYRELIG"
     gene            complement(30359..31669)
                     /locus_tag="PK679_05830"
     CDS             complement(30359..31669)
                     /locus_tag="PK679_05830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HPC55512.1"
                     /translation="MSTLILGGGLTGVTLARLLHERGHDVLVLEGEPCIGGLCRSRSA
                     EGFTFDTGGSHIIFSRDAEVLDFMRRVLGENQETRTRNTKILYKGILVKYPFENGLAQ
                     LPREDCFFCLNEYIKAYIKREKGEAGTPANFREWIYATFGKGIAELYMIPYNEKIWNF
                     PTERMSAHWVEGRIPMPPVEDVIRSAIGIETEGYTHQSVFSYPARGGIEALVRAMGNG
                     LEEKIVTGFPVRSLRFRNGAWEAGDGRRTFSGDRLISTIPLQALVRCLEGVPAEVTTA
                     VESLRYNSVACIQIGIRGSVPPLSWVYIPDRDISLANRISFPSNYSRHVAPEGCSSIL
                     AEVTFNDGDPVSRMTDSELAGHVIASLGKMGFLSEEEVIYRAVDRQKFAYVVYDLDYP
                     RNIRLVREYFEGRGITLVGRFSQFEYLNMDGCIRKAMECVEGWS"
     gene            31817..32242
                     /locus_tag="PK679_05835"
     CDS             31817..32242
                     /locus_tag="PK679_05835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase ligase N-terminal
                     domain-containing protein"
                     /protein_id="HPC55513.1"
                     /translation="MNGDRRDGKERPGRKDGSFFSFVVQEHHARTHHYDFRLEHDGVL
                     KSWAVPKGMPDLPGQRRLAVETEDHPLDYATFEGVIPEGEPGAGTVLLWDHGTFRILS
                     WEKDRIEVFLEGQRLQGKFVLLRFRKAGEKDWLVLRAKN"
     gene            complement(32279..32782)
                     /gene="ilvN"
                     /locus_tag="PK679_05840"
     CDS             complement(32279..32782)
                     /gene="ilvN"
                     /locus_tag="PK679_05840"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HPC55514.1"
                     /translation="MKPHTLSVLVENKPGVLSRVTGLFSRRGFNIESLAVGVCEEPGM
                     SRITIVCIGDDAQIEQVMKQLNKLIDVIKVSDLTENDRVERELALIKVNAEPGSSRAE
                     IMQLASIFRAQIIDVGSRSVVLSVAGDTKKIDALEKLLRQYGVKELVRTGTIAILRGS
                     KTVKSAK"
     gene            complement(32779..>34337)
                     /gene="ilvB"
                     /locus_tag="PK679_05845"
     CDS             complement(32779..>34337)
                     /gene="ilvB"
                     /locus_tag="PK679_05845"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005948 - acetolactate synthase complex
                     [Evidence IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HPC55515.1"
                     /translation="RHILVRHEQAAAHAADGFARASGRVGVCLATSGPGACNLVTGIA
                     TAYMDSVPIVALTGQVPTNLLGNDAFQESDITGITMPITKHNYLVKRTEDLGHVVREA
                     FFIARTGRPGPVLIDLPKDVSTKEIDFEYPESENVSLRGYQPTYRGHSRQIDRALELL
                     LEAERPLLYIGGGVISSNAAEELLQFAESLMIPVTTTLMGLGAIPCDHPLNLGMLGMH
                     GTRYANYAVTESDLLIAIGVRFDDRVTGKLDTFASQAKIIHVDIDPAEIGKNKRVDVP
                     IVGDAKSVLKEMIARIQKKKDYEKWLARIRAWKEKYPMRYPKDGSLRPQFIIEELSAL
                     LKGEGIIVSEVGQNQMWTAQYFGFKKPRTWITSGGLGTMGYGFPAAMGAHFARPDEVV
                     FDIAGDGSFQMNIQELGTVSHYRIPVKVAILNNRFLGMVRQWQELFYDRRYSYTELPP
                     VDFVKVANAYGIDGMRVEDPSDVRAALSTAIETDGPFVLDFRIEREENVFPMVPAGAA
                     INEMIGGHCE"
BASE COUNT         7146 a         9785 c         9711 g         7595 t
ORIGIN      
        1 ttgctgactg caatgtcggt ttcagtccag ctgcacgtga aggggtcata aaggcatgca
       61 tgggtaaaga gagtgtcgac cggttcctgc ccgagggccg gaccgatgca ctccatgcgg
      121 gagtaagtcg ggaataaatc ctgcatcagg gataactgga acgtggttct aaaaagaacc
      181 ttggcatggg taaggatgcc cccgctttca aagaaagaga aaggacaata ccttcctgcc
      241 ccctatagtt tttcatatgt gtcaggaatt ccccgcgtgc ccgtggaagg ggaggttttc
      301 tccgtgaacg agattctcat tttcggcgtg ataatcgggg gaattttctc ggctatcgga
      361 agtgctgtcc tcgtccacat gggtgaatta atagaccggt tccctgtgga gggcgagggg
      421 gagcgggaga ggagcatgtg gagcccccgt gaattcacgc gatatgcagt aatcttctac
      481 tggccactct acattgtggg ggctgcaatg atgattcccg gaacgagggt gcttacagta
      541 gggggaattg ccataatatt tggcttggtg cttttcatgc tcactgcact tgttttttca
      601 gtcgcaacct acaacctgat gcagtcaggc cgggaaaaga gcacgaagca gcgctttttg
      661 ggttcattct tcggcacgag aaacctgttt cgggtctccc catacagggc gggaagtttt
      721 cgcagcagga aaaaggagaa agatagcggg aatgataaag acacacgcga aaaacaggat
      781 tgaaagatgc tttttctccg gcgaaaaaca ggttaaggga tgaattttta tccaaacaat
      841 gcgcgggacc gctcgagtgc atcgactgcg gggagcttct ttccggtgag gaactcgatg
      901 catgctccgc ctcccgtcga tatgtgcgaa aaatccttgt caatgcccat cttttccacg
      961 accgctgcgg tatgacctcc cccgatgatg gagaactcca ccttcgatgc tgcccggaga
     1021 agttcatgcg tccctgttgc ataatcgggg tcttcgaaga cacccgcggg cccgttgaag
     1081 acgacggtcc ttgaggaacg gatacgttct gcaaggcagg agatcgcatc cattcccgcg
     1141 tcgaggatca tcgcatcccc gggaatcgag tctgcagggt attccaccct gcgccccccc
     1201 tccttgacag caacggagcc tggatacatg atccggtccc tgtaggagtc gaggaggaga
     1261 cgggcccgct cgacctcctt ttcgtaaccg agctgctgga tgatctggtc cgatcccctg
     1321 ccaatcctga accctgctgc acgcaaaaag acgtttgcaa cgacacctgt cacgatgacg
     1381 agatcggcaa cattgttggg aagcacgtac tctgcgacgg agagggaatc gtccaccttt
     1441 gtcccgccaa gaaccatgca cacgggcccc ggcgcgttct caaaaaccct gctcagggtg
     1501 gtgacctcct tttccatcag gaggcccgcg acagaccgca tgaccatggg gagaccgacc
     1561 atcgtcggct gggagcggtg tgatgtcccg aaggcgtcgt ttacgaagat atcccccatc
     1621 tgggagagct tttggacaag gtgggttttc gatgcctctt ccggctttag tttgagattc
     1681 tcttcggcat tgaacctgac gttctcgagc atcaggacgt cgccgttctt catccgccgc
     1741 acggcatcgc gggcacactg cccgaagata tcgtcgatgt acctgacctt tctctggagc
     1801 agaccttcca gtctctcggc atgcccttcg agcgtggtaa aatccttctt tcccggcctg
     1861 ctctggtggg tgatgataac cacgcgcgac cccgagaggg cctggattgt ggggaggtgt
     1921 tcgcggaatc gtttgtcatc gaggatgtga tgggttgccg ggtcaatggg ggaattgaga
     1981 tccagccgga ggagcagggt cttgttctcc ggccggatat ccttcagcgt cccgattggc
     2041 atcactatcc ctcccccgtt tcaggtggtc cttgccttga tcttcttcaa acggaagagt
     2101 tcttcccttt ccatctcgtc aaggcgcatc ttgatgaagt cacgggctgc cgtcatctcg
     2161 ggaatgacct tgaactcgag tgcgtttacc ctgcgcttcg tggactctat ctcgtcgaga
     2221 agccgcttca tggtcgtctc cacttccgcg ctgcggatga tagcctccac cagctcctcg
     2281 aatgcgagcg ccgtctcgtc gatgacggga gttgtcccga ggataccgta accccgttcc
     2341 atcaggcctt ttttgacttt cgatgcatcg atctcgggga ccaccacacc catgatgttc
     2401 ttgctggcca cggtgattgc aggaacctcc tggacggaaa acgctgctgc cttgaccccg
     2461 atggccccct cgacggtgtt tgcaactgcc atcagttccc tggcacgttc gtatttttcc
     2521 atgaggtcgc cccgggtgtc ctttgcctgc tccagcacct tgaagaactc caggataagc
     2581 ccatccctct tcatcttgag gattttatac cccctctcgg agagtgctat cttcttcttg
     2641 aggttgatca gttccgaccg cgtgggcttg atatctcgga gtgccatgtg gatctacccc
     2701 tctgcctttg cagtctgccg gaacttgggg tggtacttgt tgatcaggtc acggtcgata
     2761 cggacgagct gttccacggg cagcgttgag aggaggttcc acccgaggtc gagggtttcc
     2821 tcgatcgtgc ggtcttcagt gtacccctgc cggacaaacc tgttctcgaa gaggtctgca
     2881 aattcgagga acatcctgtc ccgctcggag agtgcgtcct tcccgacgat tgcgacgagg
     2941 ccgcggagat cgttgccctc agcgtaggcc gcgtacagct ggtcggagac cttcttgtga
     3001 tcctcgcgcg tgtggccttt cccaatcccg aggttcatga gccgggagag ggatgggagg
     3061 acgttgatgg ggggatagat acccttcctg tggagttccc tgctgacaac gatctggccc
     3121 tcggtgatgt acccggtcag gtcgggaatc gggtgcgtga tgtcatcccc cggcatcgtc
     3181 aggatcggga actgggtgat cgaacccttc ttgcccttga caatgcccgc cctctcgtag
     3241 atacctgcaa ggtcggtata catgtaaccc gggtaaccgc gccggccggg cacttcctcg
     3301 cgggccgcgc cgatctggcg gagcgcctcg cagtagttcg tcatgtccgt caggatgaca
     3361 aggacgtgca tcccgagatc gaatgcgagg tactcggcgg tcgttaaggc cagacggggc
     3421 gtgatgatac gttcaacggc aggatcgtcg gcgaggttca ggaagaccac tgcacgctcg
     3481 agcgcccccg tccgctcgaa gtcctgcatg aagtagttgg cctcttcctt ggtgataccc
     3541 attgccgcaa acacgacggc aaaggcttcc ttggatccgg gcacctttgc ctgtcgggct
     3601 atctggagtg cgatctggtt gtgcgggagt cccgctcccg agaagatcgg gagtttctgg
     3661 ccacggacga gggtatttgt cccgtcaatg gttgaaatac ctgtctggat gaagtcgttt
     3721 ggagatccgc gggcataggg gttgattgcc gcaccggtga tgtcgagccg tttttccggg
     3781 actatctcgg gtccgccgtc gatgggtttt ccacctccgg agaggatgcg cccgagcatg
     3841 tcccgcccga ccggcatctt gatggtctcg cccgtgaagc ggatgccgct gtccctgcct
     3901 atcccggcag tcgtctcgaa gacctggacc acaacgagct cgtcgctcgt gtcgaggacc
     3961 tgcccccgct tgatggaacc atcgtagagc acgatgttga ccagttctcc gtacccgaca
     4021 ggctccgtct tctcaacgaa gacgagggga cctgcaatct gggtaattgt cctgtattcc
     4081 ttcatgctgc cgacctcagt gcattgaact ctgattccat atcggcctgg atctttgcga
     4141 gcgccgggac gtagtccttg atgaacttga tctggggcag ctcgttcttg gacctgactg
     4201 aaaggatctg ctggggtgtc acgcccgcgt tctgggcagc gtaggcaaga tcagagtact
     4261 gccgaatcgc cttcatcatg tcgtactgct tcttcatgtc gcagaacgtg tcaacggcat
     4321 cgtaggcgtt ctgctggagg aagatctcgc ggatcatccg cgccacctcg atggtaatct
     4381 gctcggcctc cggcagtgca tcggacccga cgagctggac gatctcctgg agttctgcct
     4441 ccttctggag gatctccatc gcccatgagc gcagggagtt ccactcgggc gagacttccc
     4501 tgtcgtacca ctcctgcagg ctgtcgaggt acagcgagta cgagttgagc cagttgatgg
     4561 cagggaagtg gcgtctctgc gacagcttcg catcgagtgc ccagaacacc ttcacgatac
     4621 ggagggtgtt ctgcgtgacg ggttcggaga agtcaccacc gggtggcgag acagccccga
     4681 tgaccgagac cgatcccatt tttccgccca gtgtcctgac ccgccctgca cgctcgtaaa
     4741 attccgagag gcgggcggca aggtatgcag gatacccctc ctcgcccggc atctcctcga
     4801 gacgggacga gatttcacgc atggcttctg cccagcgcga tgtcgagtct gccatgagcg
     4861 agacatcgta tcccatgtcc ctgaagtact cggcgattgt tatcccggta tacacggatg
     4921 cttcccttgc agcgaccggc atgttgctcg tgtttgcaat cagcacggtc ctttccatca
     4981 ggggttttcc tgtctttgga tcctcgagtt cggggaactc tgtcaggacc tccgtcatct
     5041 cgttgccccg ctcgccgcac ccgatgtaga ccacgatctc ggcatcgctc cacttggcca
     5101 gctgctgctg ggtcaccgtc tttccgctcc cgaacggacc ggggatggcc gccgtgcccc
     5161 ccttggcgat cgggaagaga ccatcgagaa tacgctggcc ggtgatgagc ggaaccgtcg
     5221 ggttcatctt ctcgaggacg ggccttggga cacggaccgg ccatttctgc atcatggtca
     5281 gggacgtccc gtcatccagc gtgcagataa cctcgtcaac ggtgaatgaa cctgacctga
     5341 tactttttac cgtaccaccc ttgacattgg gaggcacgag gatcctgtgg acaatgtttg
     5401 tctcctggac ttccccgatg accgttccgg gcccgacttc ctgcccttcc ttgacgaggg
     5461 ggcggaactc ccactttttc gagtggtcaa gaccaggcgc agacacaccc ctctggatga
     5521 aatcacccat cttgtcaacg agtacggaca ggggccgctg gataccatcg tagatactgg
     5581 tcagcagtcc cggcccgagt tcaacggcaa gggagagccc tgtgttgatc acaggttcgc
     5641 ccggccgaat gcccgaggtg tcttcgtaga cctggatgat gatattttca ccctggatct
     5701 tgatcacctc tcccatgagt tcttctttac cgaccttgac cacgtcgtac atgtgggctt
     5761 caattcccac agcagtgacc accggaccgg caattcgctt gagaacccct gtctttgttg
     5821 tctttgtgtc ctgtgctttc acttccacag atcaacaccc actgaacgct ttatcctctc
     5881 cctcatggag agaccccctt cttctgctcc gatcgtgatg accgtcggtt tcacggactc
     5941 ttcaagggtc atctgcaacc tccgcgggat cttcctgata tctccgctct gcaggaccag
     6001 gattcccact tccgggtcat cgaggacgcg gttgatgtac tccacgagtt tctcgtcgct
     6061 ctccgccgga taggtcttcc ggatacccgc caggcggaat ccaaggatga actcctggtt
     6121 tcctatcact gcgatctcca ttataccacc agatatcccc ggattctttc aggcgcaagc
     6181 ccggattcct tcccccttgc aagggcccgg agattgaaga tctcgtactt cttcatctcc
     6241 aggtaggcaa ggatgggatg gatggagaac gggtggagtt tagacatggt ctccatctcg
     6301 gcaagctgca ccttgatgag ttcgatctcg atctcacgaa gcgatctctc ctcccggagt
     6361 ttctccagca gctcccggag gggcctgacc tttatcaggg gcacgagtgc atcgatgaac
     6421 tcgtttgtat cctttatctg gaatacccgc tggagtgcct ggggtgaaat cgttcccccc
     6481 gcaatgagga ctccggatat atcactcacc gagggatcgg cccggacgcg gaatagtgtc
     6541 ctgatgttgg tgatatcgat atccagagtg atgtagtcga ggaactgcct gccacccttg
     6601 attccgctgt gagcatatgc aatcaggtcg gcgtagaact gcttgtagag ttcgttctct
     6661 acctttggaa ggatctcctc cctgacaccc ccctccgtca tccgcgacag gatcgggtag
     6721 atacctttcc ccttgagggc ttcgatcacc cgctcggggg ttggttcttc gagaagcctg
     6781 tcgagaaata ccctgtcaag ttctcctgca ggtaccagga cttccctgat cttccctttc
     6841 ttctctccgt ggagcttgcc ccggatgatt gtcaggacat tctggatgtc ccaccgcctg
     6901 agataggcac gggtcaggtc cttgagtgtc ccgggtgtga tcttctggat gttctggtac
     6961 tcctttgcga gattccacga cagtgccgtt tcgatgaggt ctattccccg gaaagaagtt
     7021 gccagttcat ccacttctct cttgtactgc gattcaccca cgaacctcgt gatctctgca
     7081 agccccatgt tcagcatccg catgtattcc tcgcggggaa ggagtttgga cttgcgcacc
     7141 cgcatccttg tacagacata gatgtagggg accgggccgg ctcttatttc tgccacgtga
     7201 gcacccccct atccaaagag caggtctgat gcatctttga gtcctgattc ccaaaccatg
     7261 tccaggaatg tgtggtaact gtaatcgagc tgcaggctcc catcctttct ctcgacgatc
     7321 accccgccat caatattggc gtcacttccc actgaaaaag atttgaactc ggggttctgg
     7381 gcaagaacct gttcaaggac tttgcggtca cggggattga cgtgcacgac accctccccg
     7441 atctgggttt ttgcctcttt caggaggttg gtgatggcct cgcggtggaa gctctcgggc
     7501 agacctgcga ttaactcctt tgcgcggagg tatacctggt caaggagttc cttctgggtg
     7561 ttgagcaact cccgctttac ctggaggttg gctgccgagg cttcctggtt catgacgtac
     7621 gcggcctgcc tctcgacctc ctcgtttgca gcctgcttga tctttgcggc acgttcctgg
     7681 gcagccgaaa gaaccctggt agtctcttcc tggctctctc tcctgatcct ctctacttcc
     7741 tttctccctc gctcgcggat ctcctcaagg actgcctcca atcccatggt ccgctcccta
     7801 gaagagtaac aggagtccga ccacaagacc gaagataacg atggtctcag ggatgacagt
     7861 gagcaggaga accagcccaa agatgtcctt gttctcggcc gtggctccca ctgcggcaga
     7921 accgattgcc atttcggcaa gaccggtccc gatacccgtg agcccgacag cgagccctgc
     7981 accgagggct ttcattccaa gctgcgatgc cttgaccatt tcgacggtca tttctgttgc
     8041 tgctactgct gctgcttctg ccattttaat cctccataaa tctctttttc atcccgaaag
     8101 gattgtattt tctgcctcca cccttgtaga acttggtgaa gaattcaacg tactgtaacc
     8161 tgagcgactg gagtgccccg ccgagcatcc cgaggatcgt gtttaagaga tgcccgacaa
     8221 cgaggacgat gccgccgatg atgatgaaaa tgacccccaa tgcggtcagg gactcgagct
     8281 ggggttcaat gatcagcccg atggcgatga agttcacaac catggcaata gccacggacg
     8341 agagcccgac gcccaccaga cgggcatagg aaagaacgtg gctcaggatc gtcggcaact
     8401 cgaccacctc gaggggtgaa tccaggatga tgaaaaggac tccggccacg atcatgacga
     8461 gtccgccgat cgaggcgagg tttaacccca tcccgatcgg tggcatgccg gtcaggtcag
     8521 gcatgaacgg catcgagaaa gatgcccata tcatcagcag gataccccag aggaccatga
     8581 tccatccgag gttggcaagt actgccttta ccctgtgcga tccgtggtcc tggcgggcat
     8641 ggttgaccat cccgagcacg cgtccgagcg tgatctggag gatgccgatc catactgcca
     8701 tgatcatcag ccccgtcacg tccgggccgt gtccgcctgc atgacccccg atgttgaggt
     8761 gccgggagaa caataacggt ttccagggga gcgagaaccc aaatatctcc gagaagagga
     8821 taccgaagat aatactcgat atgctcgcgt tccggagaat gatggcaagc ctgcgggctt
     8881 cctcgccctt caggaacctg tgcagggcaa ggctcaggac aagaaggact gcgccgtaac
     8941 ccacgtctcc gaggattatc ccaaagaaga tgggaaagat gatcgagacg atcagcgtcg
     9001 gatccagttc agtgtaccgg ggccgtgaat acacgtccat gagcatctcg gtcggtttgg
     9061 cgaaacccgg gttatggtac tctgtcgggg gaacgtccga aatctcggat ggttcgcact
     9121 cgtacacgaa gacctttccg ccggttgcgt agtgaatccc ctctttcagt ctctccagat
     9181 ggactgtcgg aacccacccc tcgacgacga atgaccggcc cgtcgttgca aaccgcaggg
     9241 gtgcctcggc catctccacg tctgcactga gcagttcgtg gcaggcgagg aagagatccc
     9301 tgtggcgcgt cctgatgtca tcgagcttcc ggttgatctc ctccatctca cccttcctgg
     9361 caaggatctg gctttcataa aacccgatcc ggtcccgtgc gaggccgtcc tcgtcaggaa
     9421 tgggaacggc ctggaactgg gcctcgggaa gggcctggtc gacacccgcc ctgtctttct
     9481 gctggaccac gatgatgacg aatttcccct tcttcgtatc ggcggaaaat atctcgtggg
     9541 gtacatcaag agagagactc tttgagatgt acccgcaata taccgagaac atccgaaaac
     9601 cccggaggag cgaaagatca aacgggacgt cctggaaagg acgcagcgtt tcaatcttct
     9661 gctcgtactc ctttatctgg gcatcgagtt ttgccctctt tgcaaggagt tcctcggttt
     9721 cctgttcgag gaggggaagt tccttctcga tcacttctct caggtgcgag ctcttcactt
     9781 tctggcttac agggacctct tcgtcctcgc ggataccaaa tgaactggtg attccccgga
     9841 gcctgatcaa ttcacgggaa gtttcgtttg ccgcagggag gggggtacct atccggtacc
     9901 cctcgtactc tttgctgtct ttttcaacga attcttcgat gtgaaacagg tgttgccggt
     9961 acaactcccg gataacaggc tccatctggg atttcgtggc cgcaatgagg acacgagtca
    10021 tcccttcagg agtgaacatg gagccgctcc ctgaaccgcg atacaaggag agaagcagcc
    10081 ttttcaagat tgcgggaacc cctctgcctc aattcggcag cacgtgccct gccatccttc
    10141 aggatctcct cgcgtctcct tgccgcgttt tccctgatct cggccattct ggcctttttg
    10201 tactcctccg catcgtgcgt tgccttcata atgaggttgt cagcttccag ctcggcgtga
    10261 gcactggtac gctttgcttc ggcgaccgcc tcgctgatca ttttttcata ctcagattca
    10321 gtcagtttaa tcttctgcaa gacctcagtc ttcatccaac cctcctctca cggcattgaa
    10381 ttgttagacc ggaattgttc ttatatctgt tgatattttt cggggaaaag tgggtgttgg
    10441 atggttcaaa atcaaaacag aagtttttta aggagaataa gggagattac ccggattccc
    10501 ccggcaggga atcgggcccc ctcccgcctc ccgcgggggg ccacctgtcc cgggttttat
    10561 ccggccggtt tttcgggaag ggaataaccg tcacttccgc cgaatgtgga cagttcgtga
    10621 tgcgaattcc cgattcacga ccctcaagga gaatccccgc cagttccgcg gatgaacaga
    10681 ggagatcctg ttccgggtga gtcccgcgaa cgatggcgca ggagaggaga attcgttcgc
    10741 cggcggagac aacataccgg agcctccgcg accccgggtg atcctttcgc atgacgagga
    10801 gagggaggtg atggtcccgg acaaggcaaa aaagcatcga tgcagccgaa agcgatcccc
    10861 cttccggtgc agaaaccgcg atgatgtgat gcggccagac tgactggcag tattcgtcgt
    10921 caggagtctc gatgcaaagg ctgaagcggg tcccggcctg ccctgcgacg atgaaagagt
    10981 tctctcccct tatcaggagc agttcgtcag gaccgggttg tacaacgggg caatacaagg
    11041 gacaatccca tcctttcaga gcacgaggtt gaaaatcacg agggcgatga ccagcatgat
    11101 gcacgagtgt ttcactcctg ccttgaggga cccctctccc atctggcctg cgatgagccc
    11161 ggacatcaat gcctgcagga cgacggaatg gtacatcagg cgcaggattg ccttgatgga
    11221 agaggagctg atactggcga ggggtgttcc ctgcggaatt gtcccgccgc cgacgttccc
    11281 gaggatgggg atgaaactgt tcgagatgac acccacgaca aagacaaaga ccacgaatgc
    11341 catgtaaata atcgcggtat agatgaacat gtccgagagc cgctcccgct tgagaaggtc
    11401 tgacatcttt gcgtcgctgg cagcaatcgc gaggacgtca ccgatggacc cgctcatctg
    11461 gcttgccttc gtgatgagcg aaacggtacg ggcaatcagg ggagtccgca cgcggtcctc
    11521 gaaacggacg agagcgtctg caaaactggc cccccagtcg atatccctct ttattctcct
    11581 gatctcgtag gaaagaaggc caagattcgt gttgaccatg atcgagattg cctgcgcgat
    11641 cgtgagtccg acctggttga tccctgccat cctttcgagg aactcgggga tgagtgcttc
    11701 catcccctcg atgttccgcc tccacatctc gtaaaagaac gagtacggga ggagcacgat
    11761 gagaagggca atcatgacat ggtcatcgat gacatcgata tagatctcga tgtcgttgta
    11821 ttgcgggacg acgagaaaca gggcaacgag gtaaaggaca gcaaggggaa cggaaaacag
    11881 gagggtgtaa ttataattct tgacaaagaa ctcgaatggg tgccggaaga attcccggat
    11941 tctcctcacc ctgtcatagc gggcaagccg tgaaaagaac ggttcctccc cttcacggtg
    12001 gtaaacggga acatcgctgt actcgtggag cagttttgcc cgcacgaacc gttcgacgac
    12061 ctcacttttg agtgaaatga ggtcgatgag gaggatgaaa acggcagaac caatgggaaa
    12121 gacgaggtac acgacagccg tcagctggag gattgccatg cctcccatca ttcccatgac
    12181 gaccatgatg atgatcaaga acaggggacc ggccacaaag agggtgacat aagactcggc
    12241 gacgagggaa agaaactgga ggaactgttt ctgctcaaaa cgtgcctctt cctgatagag
    12301 ccggaccctt ccggagagga aaccgacgag gtcaccgccg ctctcgatga cagagacaag
    12361 gtcctccagg aactgtttca tcttctctga cggggttgtc ctgatcaggt ggcggagggc
    12421 ggtgacgagg tcgtacccga agaaatcagc atcgcggaca acctgccgga actcgagggc
    12481 cacttcaccg taaatctttg cgttttccga gagcgaacga aagattgtca tcatctgggc
    12541 cccgcccttt ctcatcgcgt acatgtatgc aaccgcgtta tggagggtca ggttgatctt
    12601 cgtggccctg tttttcttct gcatcgaggg atagtgcagc gcgataaggt agacgatcat
    12661 gaaccccatg ataaaggcaa caatggctcc cgtgacctgc agcggcaatg cgtaggcgga
    12721 ttgcggctcg attttttcgg ggaagggaat ggaaaatacg ttgtatacac ccgtgtaact
    12781 ccctccccct gcggtgtaga caatgattcc ggtgagccag aaccccagca gggcaaaagc
    12841 aatcccggta gccaccccga tctgtatggc acgcgcaagg tatcgttcca cagtgacgcc
    12901 gaaacgggcc gattcaagat cggattcgag tttctggtac ttgagggggt tttgcctgac
    12961 ccggtttctc aggaaggaat tgaggctcat tccagcactc gtgagaggtc ctcgaggttc
    13021 ccggtcacac tttcgggatt gatgtgatat gcctggaata tccgggatgc cctcacataa
    13081 tcaatgatac cctgcttctc catggccagg aggatactct tccgtgtcgc gatctcggcc
    13141 tcgagtttct cccggctcca tccccgccgc tcggcaatat ctgcgtaaat ctgggacctc
    13201 cccttgtacg tgaagacatc atggaccgga tcgtatacaa agacggtatt gacacggagg
    13261 ttcccggtcg agggatcgat cccggcgatc tcgacgatct cgagggatcg ccggacacgc
    13321 tcggttcccc ggtaaatcag ggcctgcaca ctgacgatgt tcaatgccgt gatcatgttc
    13381 cggggaacgt tgagcggctc gttctcgagg cggtggatgg cggcgtccac gcttccggcg
    13441 tgcatggtgg aaaacgttgt atgccccgta ttcatagcct ggaaaagtgt ctgtgcctcc
    13501 actcccctga cctcgccgac aagaatgtat tccgggcgct ggcgcattgc agcccgcaaa
    13561 agatcaaaca tggtgatgat gtttgcaccc tccgagacca tttcgcgcgt cacgcttgca
    13621 atccagttct cgtgaaagag ggtgatctcg cgtgtatcct cgatgctgac gaccttggcc
    13681 atcggtggga tgaagaatga gaccgcgttg agtgacgtgg tcttgcctga tgctgtcccg
    13741 cctacgaaga ggaggctttt ttgattctcg attgcgagcc agaaatagac aagctcgtca
    13801 acgctgaacg tcctgtactg caacagttcg acgggggaga agggttcctc cctgaatttc
    13861 ctgattgtaa acgaggtccc gcgtgtcgtg acctctgtcc cgagggtgag ctggagcctc
    13921 gagccgtccg gaagagttgc atcgagcatc ggcgtcccgg tggaaatgtg ttttccggag
    13981 cgctgggcaa gtgttatggc aagcgagttt aagacctcgg gctcaaacat gatattcgtc
    14041 ctgacgttgc ggaacttccg gtgatagaga aagaggggaa tcctgtgacc atcgcatgag
    14101 atgtcctcga gattgcggtc cttcatgagg gcatcgatcc ggccccaccc gatgaaattg
    14161 cgggtgaggt agtactggat gcggaaaatg ctcttatcct cgggttttat cccgtactcg
    14221 tgcagaagtt cctgcatttt ttcaaggagg agcgttctct tgtccattgc aatttcgtcg
    14281 tcggtaagga tgagggccga gcgcatgtct tcatggagcc tctcgagcag ttcgtactcg
    14341 aactccgata gttttggttc gaagaggagg tactcgtact ggttggtctt ttcgttcagt
    14401 gcaatgacaa caagtgacct cccttcatcg acgtagtacc gttcgacctc actgtaacgc
    14461 ggcggaatct cggcgtcgac gagggttccg tcacgtttga agtcatactc gggaaaggag
    14521 acagatgtct tttttttctt caggaacgat gtaaaggaga attcgggagg tgcggtctcc
    14581 acaacgtccc ccccgctgac cggtctgagc cgttttacca cgccatgaat atccggtatt
    14641 ttgagagcca ctggaacgac ctgccctgcg tctgcgaaaa aggacgctca aatcctttag
    14701 gatgtttttc ccgcacaggt atataaaatc atgacggaag gggatgcggg agtttcccat
    14761 ggactgccat acgggatgta actatttttg ggtaaaatga cagaaatgta catgtaccct
    14821 taaaaactca tgataccaca acggaatacc gaggttccca atggacgatg acaaggcaca
    14881 caagacgctg atgccgaccg gaatcccttc cctcgacccg gtgatggaag gaggtgtccc
    14941 tgcgggctcc cttatcctcc ttctcgggga tatcggcgca gggggtccgg agtttgcata
    15001 tacctccgtg atgctccttt cccgcctgat tcacgacaaa ccggcagaca cagagacgat
    15061 cccccgggag gtctggtatg tcacgttcac gaaaggaaaa gaggatgtcc tctcggagat
    15121 gacactggcg tttcaccctg acctcacaag gggtatcacg gatataaagt tcatcgatct
    15181 ttcccagatc tactttgatt caagcatcgt cccgctcgac tggtattcga aaaaggatat
    15241 cttttcgcgt ctccagtcgc gggggggaca cgacagtatc ctcggggcgc ttgcaaccaa
    15301 ccttggtaca atcccccccc gcagtctcat cgtctttgat tcccttactg accttgccac
    15361 ccagtatgca aaggacggca tctggagtga ttttgcagct tttctccgcg ggctccagag
    15421 ggtcgcaaaa gagtgggaat cgacggtgta cctcatcctc acgaggggaa tccttgataa
    15481 ttcccgcgag ttagaaatat cagatatatc ggatgctgtc atcttcttcc gctgggagga
    15541 gacaacgggg ggccggcggc agagggtgat gtatttcgag aagttccgtg ggctcatgcc
    15601 ccacctcgag gaaaacgacc tcgttaaatt tgccgtgcgc atatccacga acgagggttt
    15661 cgacgtgagt aacatcagag tggtcatatg ataggggggg agcgtgtcag gattgggata
    15721 gagggccttg accagatgat ggggggagga cttatcccgg gcagtatctg tgcaatcatc
    15781 ggcacatacg ggacgggtaa gacgacgttc ggactgcagt tcgcgtggga gggcctgacg
    15841 aacggtgaga acgtcatcta catcagcctc gaggaacgcg aggacaggct ttttacgtac
    15901 atgcaggaca agggatggga tatcgcgccc ttttctgacg gaaggttcac ggtgctcaag
    15961 cttgacccgt cggacttcaa tcttgccatc aacagcatca agaacgagct tcctgccctt
    16021 gtacgccaga tgaaagcaaa aagggttgtg attgatcccg tctccctctt cgaagacctc
    16081 ttcgaccgcg attctgaccg caggcgggag atgttccggt tcatcgacac cctccgggac
    16141 cagcagtgca caacccttat gacgagcgag acggacaaga acaacccttt cgcaagccgg
    16201 cacaaccaca tcgagtacct tgccgatacc gttatcctcc tgcggtacgt ccgtccgtct
    16261 gacctgacag atgtccacct cgcgctggaa gtcgtcaaaa tgaggctttc accgcactca
    16321 cgcgaaatca agccctacga gatccagcag aaccaggtcc tcgtttacac ggaggcaaac
    16381 gtcttttaaa agggagccgg gtttttaaaa tccttcaaac ccgatgagat ggagcacgat
    16441 gacgatgagt gcccccggga tccctccgag gatgcagagg agtacattga ccagggagta
    16501 cgggatgtcc gcccttccca tgacgtgcat gaaacccatg aggttcacca aaaagagtgt
    16561 caggagcccg agaaccgagt tgatgataag tttcgtgatg tcctttaaga cgaagaagag
    16621 cacgacagca atcaggactc ctgcagcaag gacagtgtaa tcaaggttca ttcttaatta
    16681 ccaatgattt tctggttttt taatcttatc gagggaagga cacagcatcc gacgactttc
    16741 tcctctcccg acagaccacc ggtttcgccc agcatctcaa aaacgttccc ggcaagcatg
    16801 gccttccgga cgggatactc ggggtttcct ccccggtaca gatacgcatt tgccagttcg
    16861 accgagaaat cccccgtgag ggggtttgtg gtatgggcac cgacaacgtc atggacaaag
    16921 attgcgtcct tttccaggat ctcgtccctc gggccgtcga gggtcatgca gtggaagccg
    16981 attgcaatac cccctcccat gcctgaacgg accgcgttgc cggtagtcat gcacccatac
    17041 tggtaagctg tcttgaggtc ataggcgaaa cagcggagga cacccttctc gacgaggtga
    17101 agcgtccgtg tcggggtacc ttccccatcc cagcggcagc tcccgatccc ccgggtgttg
    17161 gacgggtcat cgatgaagga gagagccggg tcacagacct cctgcccgat gaggtgtgcg
    17221 agccgcgacc gtcccgtatg cacgtttctt ccggagagcg cagggagaaa ggaacccgcc
    17281 atcagctgac cgaaagcgtc gggagagagc acgacatcgt aggtccctgt cggaatatcc
    17341 ttccctccgt gggacgtcgc tgcaaggaat gctgccttct caccgaccga gcccgggtct
    17401 atatccattt tccaggacgt cccgtactcg taacccgtgg attgttccct gatggtctca
    17461 aggcccatgc tcaccaggct ctccctgtct tcgcggtaaa gcccgcggga gtttgcaaga
    17521 acaatcctgt attgcgagat ctcggcactc ccggagacga tctccacggg gtacctgcag
    17581 gccccttcct ccatcccccg gaccatctcc cggacgcggt cgggatccgg gacgacattt
    17641 tcgtcgaaat tgacaaagtc accgtaattc tctgccgggc caggcagacc gtcccattcc
    17701 tgtggcgctg caagggcagc actcctgagt gccgcatcaa ggcaggcttc ccaggcctga
    17761 gggttgcccg tcgaggagac acctattctt ccacccctga tgacccggag cgagagtgcc
    17821 tggtgttcgg atccaagggc atacgatatc tcccgtttgc gcaaccttgc tgtgaccgat
    17881 gtccctgtgg cgaggtagac ctcgacctcg tcagcctgac gttcaccggc cataagtatc
    17941 ttctcaatcg tgtccactgc caccaaccac cgcgtcccga acgagaacat ggggcgcacc
    18001 atcgctcacc gggacggtct gtcccccctt tccgcaataa ccagcgtgca tcttcctctt
    18061 ctttgcgcag agttcaattc catgcagcgt ggcaaggatc tcgcccgaga gcgagacgtc
    18121 ccgcaccatg cccctgcact ccccgtgctc gatgaggtac ccgtactctg cattgaactg
    18181 gaagactccc ctcccggggt cgacctgtcc cccccgcgag ccgcacagga ggatcccctc
    18241 cctgcactcc ccgatcagtt cttccgttgt gctgtcgccc tccgcgatgt atgtattgct
    18301 catccgcacc tgagggggtt ctccgggcat ggcccgtgca ttcccggtat gcccaaaacc
    18361 cacggcaggg agggtctccc tgctgtggag ataggatgta agaacccctt tttcaacgat
    18421 gatcgtcctt tccaccctgc ttccttccgc gtccacgggt tcgaatccga actcggggag
    18481 agtcgggtcg tccacgatgg tcacgatgcc gctcccaatc tgctctccga tttttccccg
    18541 gagcaccgag ctcccttcat gaacgagatc ggcctcgctt gcgtgaccga ccgcttcgtg
    18601 cgcaaagacg ccggcaagtt cagggtcgag aaccacgttc atggttcccc cacggggtct
    18661 cttcgcgtca aggagtgcaa gtgcccgccg tgcggcggtc tctccgtctt tttggccgtt
    18721 atccagcggg aaatcctgga gggcatgcct gcgccggtaa cccatctgca tctcgccacc
    18781 gcgccctgca accgcgagga tggaataacc ggaacgaacc agtgaatagg tatactcgtt
    18841 tccacacgag tcctcgaaca ggacatcctc gtacctctcg gtatacccgg cccgggtact
    18901 cgtgatcccg ggaattcgtg cggctttctc gatcatgagg agcaaccgtc ccttctcctc
    18961 gaggtcgatt gcgagcgggt cggtcttttt tggcggcacg gggatcatgc cggacggtgc
    19021 atcggcaagg gtaacctctt cgcccgtcag ggacgcaagg gcagaggcct tcgagagcag
    19081 gtcctcgaat ttctttccgc gtgggcgttc aaaacggtcc acggtgagga tcccccaccc
    19141 tttcgggccg aggacccgga tgactgcccg gtcgagaaat gttgttccgg cagattccac
    19201 gcgtgaattt tcgatatcga tatgggatat cgcgcccttc acgtggcgga tgtcatagta
    19261 gcggatccct gccatgaaat catgccgggg atgtcgggat tcccgttccg tccaggaaac
    19321 tcccggacgg tgtcgttgcc atcctgcgca gcttgttcag gaacccctcg cggttatcgg
    19381 gaacaagggc gatcgtgagc acgtcgtcga tatagtcgac agggatgatg gtcaccatcg
    19441 accggtaacg ctcttcgatc aggacgtcgt cgaggttcgc cctcgggatg aggacagtcc
    19501 tgatacctgc cttggcagct gcctcgatct tgaaagtgac accgccgaca ggcaggacat
    19561 caccccgcac ggagagagac ccggtcatgg caatgtcctg gcggacaggg atgttttcga
    19621 tcgcgctgat gactgccgtt gcaacgctga tcgaggccga gtccccttca acgccaccgt
    19681 atgtcccgat gaactggatg tggatgtcca tgttcttgat gtccttgccg gtgaacttct
    19741 tcaggatggc actcacgttc tttatcgatt cctgtgcaat ttccttgagc atccctgtcg
    19801 cgatgacggt tccgctcgca ccctgtgccg gtgtgacctc tgccatgatg ggcaggacag
    19861 agcccgagtc gctgcccatg accgcaaggc cgttcaccct gcccacacgc gtgccttcca
    19921 cgacggtgag ctcgtactcc ctgctccggc ggatgtactc atccgagacc tggtcctcaa
    19981 tcgacctggc ggtcttcttg gcagcgatga catgttcggc agttgtcatc tcggctccct
    20041 cctggcgggc gaggtcgcct gcgaccctga tcaatccgcc catgtcccgg agcttcagcg
    20101 tgaggtgtcc cttcctgttg gacctgcggc gggcctcccg gatgacctct tcgatcgcac
    20161 tcctgtcgaa gtggggtatc tttccatcgt tcctgacttc ctgtgcgacg aacctgatga
    20221 acttctcccg gttctcggga gtatcgggca tggtctcgct catgtagacc tcgtacccgt
    20281 agcccctgat ccgggaccgg agtgcagggt gcatcccctg gatggcatcg aggttcccgg
    20341 cggcgaccat gatgaacttg caggggacag gctctgtcct caccattgcc ccgctcgacc
    20401 gttcgctctg gccggtaatg gggaactccc cttcctggag tgcggtgaga aggttctgct
    20461 gggaatgcgg tgtcagggta ttgatctcgt cgatgaagag caccccctta tgcgccctgt
    20521 ggatcgcccc tgcctcgaca cggtcatggc tcggcgtctc gagtccaccg ctctggaacg
    20581 gatcgtgccg gacatcaccg agaagcgcgc ctgcgtggga accggttgca tcgatgaagg
    20641 gtgccgtcgt ggtcgaatcg ttcgagacga tgagcttggg gatcatcgat tcctcgcgcg
    20701 gtgtggcata ccggagtgcc atgaaaacga atgccgctgc gaggatcccc atgagccact
    20761 ggccctggat gaatgcatac ccgaggatcc cgatgaggag aagcatcagg agggtgttgc
    20821 ggaactgtat ctttttcttt gcctctgcct tgtgggctgc cacgatctgc tttccccgac
    20881 cggcagggac cgtcctcacg atgggattgt tcgggtcgtc ggagttggga tagacgagga
    20941 tgtcctgcat ctcttccttg ggcagcagct ctgccattgc cttggcaagc atggacttgc
    21001 ccgtcccggg actccctatc atcatgacat gccgcctctg gatggctgcc ttcctgatga
    21061 cttcaacggc atgttcctgc ccgatgacct ggtcgatcag ggagggcggg acctggacct
    21121 gcgaggagtc ttcaacggtc acttcgaccg ggggctcatc ttcctggact gatcctgtac
    21181 tattctggtc tggcattatg agaattaacc ctcttttcgt gcttcgagat gtgatgtaat
    21241 ttattcctgc tcgtttaagt actttcagca tgaggatgga gacatgttgg tcgtgagcac
    21301 ggaatattcc caggtactgg cagggagaat cgcgggggcc ctggaatgcc ccttgggcgc
    21361 agtccgtttc accaggtttc cggatggtga acattacctg cgcctggaga gaacggaccc
    21421 ggaaatggtc gtggtgggca gcatacccga tgcagatgcc ctcgtggagc tcctcctcct
    21481 cgtggacgcc tgcgagggaa acgaagtcac actcgtggtg ccgtatcttg gttatgcacg
    21541 gcaggacaag aagttccacg agggggaacc cctcagcgca agggcagtct gcagggccat
    21601 ctccggcggt gtgaggcagg tcttcacggt caacgtgcac gacccgtccg ttctttccca
    21661 tttccgtgtc agggcacagg atatcagcat tgcaggagag atcgggcggt acctcggctc
    21721 ccgacccctt gaaaacccgt tcatcctcgc acccgacgac ggggcttctg cttttgcagg
    21781 gaccgttgca gcaacgtgcg gctgggactg ggatcacctc gagaagaccc ggatctcggg
    21841 agaagaggtc cggatggaac cccggaacct cgatgctgca ggacgtgacg tggtcatcgt
    21901 ggatgacatc atttccacgg gagggaccct tgtgaccgct gcccgcatgc tccgggccca
    21961 gggtgcaggg accgtgtcgt ccgcgtgcgt tcacggagtc cttgcggaag gggcatactc
    22021 ccgccttctt gcaagcggtc tttcggaagt cgcctgcagc gataccatcg agagggcctg
    22081 cagccgtttc tcggcagggc aggccatagc cgacaggatc ctcggatgct cgtcatagac
    22141 gggtccacgc tggaaggagg aggacagctg gtcaggtcgg cggtcacgct ctctgccatc
    22201 accgggcagc cctgccggat cacgaacatc agggcaggaa gaaaggaacc gggtctccgt
    22261 tcccagcaca ttgccgcagt cagggcggtt gcaggtctct gcggggccac ggtgtccggc
    22321 tgcacaccag ggagcaggga actgacattc tgcccgggtc ccctcgtgga aggtgacatg
    22381 aggattgaag tcgggacggc aggaagtatc cctctcgtcc tccaggcatg gcttcccgcc
    22441 gccctcatga tcgggggccg gataaccatt gctggcggga cggaggttcc catgagcccg
    22501 acaatagact atactgcccg tgtcctcgta ccgttcctcc gcaggcacgg tgcagaaatc
    22561 tctctcgacg tgatcaggag gggttactat ccgcggggcg ggggcgaggt gatggcaagt
    22621 gcccggcggt cccgccttgc ccctttttcg cccgcggaca cccgggaaac agataactgc
    22681 gggatcgtct cgtgcagtgc aggactcccc ggccacgtgg cagaccggca ggctgatgcc
    22741 gcatcgtcag ccctgttcca ggcaacgggt atccgcttcc ctgcctggaa agatacccgt
    22801 cccggcccgg gaacgggcag ctcggtcact gcatggctgg gctggatggc cgggtgcgcc
    22861 atcgggaggc gcgggtaccc ggcggaaaac gtgggcaggg atgctgcttt taacctgctt
    22921 gccgaacacc atgccggcgg cctggtcgac aggtacctgg ccgaccagct cctcatctac
    22981 tgcgctcgtg caggaggctc ttttaccagc agcacgtgca cgctgcatgc aaggacgatg
    23041 tgctggctgc ttgggctttt cgggttccgc atccgggtca cgggaggaga ggtggtgacc
    23101 tttgccgccg aagagagtgc ttgatgcaac agcctttttc ctggacatac cgctcgaggg
    23161 agaactcttc acgactcctg cagtcgtcgg ggagatcgtc gatgcacggt cgaagtgccg
    23221 cctcgaggca ctctctgccg caggcctcgt tgtcacgagt ccctgtgcct cctccctgca
    23281 gataatcgga aaagcctcat ctgtaacggg ggacgaatcc gtcctctccc gggcagaccg
    23341 tgaagtgctg gcccttgccc tcgatacagg tgctgaggtt gtaacggatg attttgccat
    23401 ccagaacgtc gcccaccacc tcgggatacc cgtcatcccc ctccagcaga ggaaggccag
    23461 gaagagaaaa tggaagttcc gttgcccggg atgcgggcgg cccgcggaag ggccgggcga
    23521 gtgccctgtc tgcgggtcgg ggctgaaaag aacacttaag tagatcgctg cacacttttt
    23581 tcccatgtcg tctctcgatg aactgatcca gaaggccagg acgctcctct ccgagggcca
    23641 cagccccggg cagatagctg acgagctctc cctctccatg gagacagtga cctggcttct
    23701 gacccagcag aagggaatgg cagttccaaa ggacgtccat attgactgga ccagtgtcag
    23761 tggccggggc ccgctcctcg acggagtggc catgatgctc ctcaagcaat actatacgtc
    23821 tcttgaggat gaggacaggg aaggcggata ctccgaccgt ttccccaccc tcgtcgtggg
    23881 gatagctgtg tccggcatcc cggtcgcgac cctgattgcc gttgaggagg acatcaagct
    23941 tgccatttac cacccggcca agcacagcac gcaggaaccg cccgttggtt cgatcagcgg
    24001 gaattttgca tccgtcaacg gtgaacggtg catcatcgtc gatgacgtga tcacctccgg
    24061 aaacacgatg caggatgtgg tcaaatacct gcggcggcac ggtgcacaac ccgttgcgat
    24121 atgcgttctc ttcgacaagc gcggggtccg tgacattgac ggcgttcctg tctattctct
    24181 cttcaaaata tcccgaatcg actgataccc cactcttttt cccgcttcaa aatggattat
    24241 tttatataga agtttaattc catcttttac agcattggag gaactgctat gcttggagga
    24301 caacctatta tcatactcaa ggaaaacgtc gagcgcaaca ggggtcttga ggcccaacgc
    24361 tcgaacattg cagcagcaaa ggcaatagca agcgcagtaa ggacgacact gggtccccgc
    24421 gggatggaca agatgctcgt ggaccagagt ggtgacgtga ccatcaccaa cgatggtgcg
    24481 accatcctcc aggacatctc ggtggtccat cccggggcga agatggtcat cgaggtcgca
    24541 aaggcgcagg acgacgaggt cggggacgga acgaccacag cggtcgtcat ggtcggatcc
    24601 ctcatggaga aggccgaggc catgatcgag aagaagatcc acccgaccgt gatcgccgag
    24661 ggttaccgcc tgggtatgaa gaaggcgctc gaagtactcg atgacctctc gattcccatc
    24721 gacccgtacg acagggagaa actgattcgt atcgccgaca cggccatgac cggcaaggcg
    24781 atcgaatcgg tgaaaagcag gctgaacggg atcgtggtgg acgctgtcat ggcaatcgcc
    24841 accagggagg gtgacaggat cactgccgat gaggacaacg tcctgatcaa gaagcaggcc
    24901 ggggacagga tggacgatgc ggagctcgtc cgcggagtcg tcatcgacaa aaagcgtgtc
    24961 agcgaggaga tgccccgcaa ggtgaaagac gcccgggttg ccctcgttgc aagccccctc
    25021 gagatcaaga agacccaggt caaggcaaag atccacatca agtcaagcga catggtgagt
    25081 gcctttactg cgcaggagag ggagactctc aagaaatacg cggacacgat catcgcgagc
    25141 ggtgccaacg ttctcctctg ccagaagggt atcgcggatg cagtcgccta ctaccttgca
    25201 aagggagggg tccttgccgt cgaagacgtc cccgagaagg acatgaagtt tgcctctcac
    25261 gccctcaatg cccagatcgt caacaaggcc gaggatctta cacccgaggc actgggaagg
    25321 gcagaaaccg ttgaggaact cgaggatggg gagttcatca agatctcggg atgtcataac
    25381 cccaagaccg ttaccatcct cctccgcggt tcgacccagt acctcctcga cgagctcgag
    25441 cgggctgtcg aggacgggac acgcgttgtc atggacgcca tggaggacgg caagctcgtc
    25501 gtgggaggcg gtgcagtgga gaccgagatc ctgatgaagg tcagggatta tgcagcgagc
    25561 gtcggtggtc gtgcccagat cgcgatcgag gccttcgcag atgccttcga ggtcatcccc
    25621 gtcacactcg ctgaaaattc agggttcaac acggtcgaca agctggtgga actcaagaat
    25681 gcccatgcca ggggagagaa atacgccggg ttgaatgttt ataccgggac cgttgttgat
    25741 atgctcaaag agggtgtcct tgagccccag cgttccaaga ggcaggcgat ccagagcgca
    25801 acagaggcag caatcctcct cctcagggtc gacgacatga tgatcacccg cgaggacaag
    25861 aaggaaaagg aagccggaaa gcctcccgaa taaggagagc tcagccggat aaaaccccct
    25921 gactcaccgt ttttcctgtg aaaagtggaa taagtccaaa ccccattttt tcaattctct
    25981 tcgccctttc tccttcgcca atcctgtctc aatcaggggg accttttctt tagcccgttt
    26041 gcaagaggtc cacccgtctc ctgcaccggt aacagaattc cggtccttta aggtcggtgt
    26101 ccccgatcca gttcgagaaa tacatcacgc acccgggatg ttcacagtgg gccagtccca
    26161 gggcatgccc gatctcgtgg actgcctcgg tgaggattcg cctccggtag accatctcgt
    26221 tgtcaggcat cccgtagaac ccgggcctga ggcgaaacgt ggaaatgagg gccgccccgg
    26281 tgcatgcaat gccgaacacg aagtggagtc ccggggaaaa gatatctgac cctgtgatgc
    26341 cgaggcagag cacgttctcc cggcgggcga tttcagccag cgagcggaga atcccgtctg
    26401 cgaggtactg gccacgcctg ctgtcaaaat actgcaaagg gagtatctgg ggatggaata
    26461 ttcttatttc tgcaggaatg agggaaggga gatcctcacg aacccacccg atgacaccct
    26521 gatcccggtt tccgattcca accagcccga ttgccggcaa acgtgccatg gttgatactg
    26581 ggtcatgatt cgacatatcg tttcaggacc aaatcatcgt aggattgggc ccggttgtga
    26641 tccgccggtg attgtagcga accatggaag gaataaagga gatgcactat ccgggttaaa
    26701 aaaagcctta ttgtaaacgg caaaagactc ctgtcaggac gatctcagta cagggcaggg
    26761 aaaaggggaa cgggnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngtacat
    26881 caggtgatgg acgagggctg caaccggaga ccacggagga aatacctttt ttcctgcctt
    26941 caccatctca ccaatctctt tgatacggct gcctgatttc atgagagtcc tttcgagtga
    27001 ctccatgtcc ggtgcatcgt acataagtat gtagtttccc ggcatccgga tggagaacgc
    27061 agcatcaagg cccctctttc cgggcccgcc tttcagaatg tgatcgagct ggctggaggc
    27121 ggcagaagct cccgttcccc ccatggtgat aaccgagaac gtgtacctgg catgggagag
    27181 gtcaagcctt tgagcgaatt ccgcaacgat ggaggggagg ccgaagaaat aaagcgggtt
    27241 tacaataccg acacgatcgg aacgtggttc tattggcccg ccttttttca tttcagagac
    27301 gataggtacg agtgtacagt caccgataac agaagaaagc cccctggcga ctgcaaggga
    27361 attacccgtc ccggtgaaat agtaaagaat tgtttccatg gattctcacg aatctgtttg
    27421 gaacagggag ttaaaaagga caggggaggt ttccatactg gtcgacgggg cccccttcaa
    27481 aaaccgggtg ttatccccgc gagcacgtgg agacgatatc gacctcttcc tcccggatga
    27541 cgctgtcctg cgggagactc tttcccccgt gcaggatcag gaccgtatcg ggaataatgc
    27601 cgatcgagag gagggcttcc tcgtacgttg ttccttccgc ccctgtatac tcgacgattt
    27661 gatgcccggg gatgatacgg aacctgcatt ttgctcccat tcgataggat tatacgggtc
    27721 gcagggaata ataattacct ccatgccgag gtagtctagt ccgggaaggc ggtagcctcg
    27781 aaagctactg gcgctctgcg cctcgggagt tcaaatctcc ccctcggcgc gtcccgtttt
    27841 catggaaacg atctgccctt ccggcctcgt cagtcccgca tcgcatattg ctttccaaga
    27901 acgtcctttt tggcagggtt ccggagtgaa accgggataa tactcggaaa catcttataa
    27961 gagggaaaag tacctctatg catgaaaaga tcactctgga ttcttgttgg catcaccctg
    28021 gtcctgtgta tctggatggc cgggtgcacg cagccatcgc aggaacagac cacgcctgct
    28081 ccgacaacga tgccggtaac gacggcagca acttccgttc caatgtctcc cacgcaggga
    28141 cctccaccaa cggcaggtta tatcgagggt ccgttacctt cccagtactc cgttgacgtg
    28201 caggtggtca ggaatacggt ggcaattacc ccgaacatca cggtctcgtt ccggggagga
    28261 aagggtatca atttcgtcca ctccatggat gtcgtcgtat cccgatccga cggccggatt
    28321 gtaaccggtt ctctctacaa accccaggtc aacgattatc tggaactcga aggtactcgt
    28381 gggaccgaca acgtcgaggt cttcattaac ctgatcacgg gggatcgcta cagggtgtat
    28441 aacaagcctg aggcgtttcg aagctacaat taaaacaatc aatgcctttt tttagacctt
    28501 tgattgaaaa acgtatgcga tccggggcgg cagtccccca gtcttcttct cccgcaaagg
    28561 cctgtttttc cctgaactgc ccgatgattc tttttatccc cggctcccgg gatccaaccg
    28621 gctttgagag gacgggagtc tttttcaaag actatggcgg gtgcatgtat ctgaaagcga
    28681 ccgcgttcac ttgtactcgc gccgcgaata ctggtatttc tcggacgacc ctccccgggc
    28741 aacgatagag atccattcgt agagcgattt cagcgttccg aacttttcgt acctgcgcat
    28801 ggagaacccg accctcatgc ggctgtcgaa cacgatcttt ccgaaccgga tcatcctccg
    28861 tgcaatttca aggtcgtccc ccgcatcgat acacctgtac atgcccgcac gcatgaatgc
    28921 gtctttccgg aaggccgtat tacaaccgag ggtatagtag aatgtacccg tgtaataccc
    28981 cacccgcgca aacgtgttgg caagggcaag cgatacgtgg ttcttgaatg tcctctcgat
    29041 ggggtccacc ggcccataga tctggacagc accggggttt tgagaaaaat cctcgaggat
    29101 gacttccagc cagttccggg gaatgataca gtccgcgtcc gttgtcgcaa ccagggggct
    29161 ctttgctttc ataatcccgt cgttccgggc gccaccaacc ttccggctcg tctggacgaa
    29221 gaccaggtcg cagaatggtt cggcttctgc aatggtctca tccttggacc cgccgtcgac
    29281 aacgatcagc tcgtactccg accttggaat ggtctggtgc gaaagggact cgaggcagcg
    29341 cccgatgttt cctgcctcat tgtatgccgg gataatgacc gatatcttca tccgatgagc
    29401 tcccggtaga gcctgacatg tttctctgca atatccctta tatcaaacct tgccgagaac
    29461 tcccgggcac cccgggcaca gcgcccgagt gatctttcgt cctcgaggag tgcgggcacc
    29521 tcgcttctct cggaaaagta gaggatgctg tcgccatata tatcccggaa ttcggggatc
    29581 tcgcgtgcga tgacgggcag gccgcacgag agggcttcga ggatcacgag cccgaatgtc
    29641 tccgcatagg acggcatgaa aaagacatcg gcagcgctgt acggtttgat gatgtcgttg
    29701 atgtgacccg ggaagataac gtttcgtccg cactgcaact tgagcctctt gatcttgtgg
    29761 taatccttgg agagtgcccc gtagggaaag ccccctatcc agacgaacgt tgaatcaggg
    29821 caggcccggg agagggctaa aaaatcgtag aggcctttcc tcggtgtctg ctgggcgaca
    29881 gtgaggacaa ccctgctgtc ttccgggatg ttgtaatcct cacggaacgc tgctcctttc
    29941 tcctcgtctt tttgaaaaaa ctcgcgatcc acaccgttgg gtatcatcgt gaccggcata
    30001 tcaggaacca ttgcagtcac ctcttcgtgg caggggcggg aaatggtgat gatatggtca
    30061 aatctccggt aaatgtgggg atacctcttg ttcaccgccc gggcgagggc aatgttgtcc
    30121 atgttgaccc tcggtgtcga gtgtgccgtg aggacagttt tgcccctgga gagacgccgg
    30181 ttgagatctg ccaacggtcc gaaggtatgg aaatggacga tatccgcgtg gttgccatac
    30241 tttttccatg tcacctcgag cccgggtatc cctttcatgg agttgtagag ggtctttgcc
    30301 accgtggagc acccgatgta ccggaagaag agcaaatcct caacgtaaaa attgaccttc
    30361 acgaccagcc ctccacgcac tccatggcct tgcggatgca cccgtccatg ttcaggtatt
    30421 caaactgcga aaatctcccg acgagcgtga tgccccgtcc ctcgaagtat tccctgacga
    30481 gacggatgtt cctgggataa tccagatcgt aaacgacata cgcgaatttt tgcctgtcaa
    30541 cggcacggta gatcacctct tcttccgaga ggaaccccat cttcccgagt gatgcgataa
    30601 cgtggccggc aagctcgctg tcggtcatcc gtgataccgg atccccgtcg ttgaaggtga
    30661 cctctgcgag gatggaggag cacccttcgg gggcaacgtg cctgctgtag ttggagggga
    30721 aggatatgcg gtttgcaagg gagatgtccc ggtcggggat gtagacccag gagagggggg
    30781 gaacagaccc gcggatccct atctggatac aggccaccga gttgtaacga agactctcca
    30841 cagcagtggt gacttccgcc ggaacgccct cgaggcatcg cacgagtgcc tggaggggaa
    30901 tcgtactgat gaggcggtca cccgaaaacg tcctcctgcc gtcccctgct tcccaggcac
    30961 cgttcctgaa ccggagggaa cgcaccggaa agcccgttac gatcttctct tccaggccat
    31021 ttcccatcgc acggaccagt gcttcgatgc ccccccttgc aggataggaa aagacagact
    31081 ggtgggtgta cccttcggtc tcgataccga tcgcagacct gatgacatcc tcaacgggcg
    31141 gcatcggaat tctcccctcg acccagtgtg ctgacatgcg ttccgtcggg aaattccaga
    31201 tcttctcgtt gtaagggatc atgtacagct ctgcgatacc ctttccaaac gttgcataga
    31261 tccactccct gaaatttgcc ggagtacctg cctctccctt ttcccgcttg atatatgcct
    31321 taatgtattc attgaggcag aagaaacagt cctccctggg cagctgtgca agaccgtttt
    31381 cgaacgggta cttgacgagg attcccttgt agaggatctt cgtgtttctc gtccgggtct
    31441 cctggttctc tccaaggaca cgccgcatga aatcaagaac ttctgcgtcc cgggaaaaga
    31501 tgatgtggga accgccggta tcgaacgtga acccttcagc ggacctggag cggcagagac
    31561 ccccgatgca cggttcccct tccagtacca ggacgtcgtg gccgcgctcg tgcagcaggc
    31621 gtgcaagagt gacccctgtc agacctccgc caaggatgag ggtggacaca ggatatagta
    31681 tgcaaccgcc ggcattatat ggttgaccat ccagaggtcc catcaggcac cgttctgcca
    31741 gtgcggagga gtaccggcag ggaaaaatgg ccggaaatcc gcatcgttcc ggggaaacag
    31801 ggaggggtga agggaaatga atggagacag gagagacgga aaagagaggc ccggcaggaa
    31861 agatggctct tttttctcct tcgttgtcca ggagcaccat gcccgcaccc accattatga
    31921 tttccggctt gaacacgacg gagtcctgaa gtcatgggcc gttcccaaag gcatgccgga
    31981 tctgcccgga caaaggagac ttgcagtgga gacggaagac catcccctgg actatgcaac
    32041 cttcgaagga gttatccctg aaggtgaacc gggtgccgga acggtcctgc tctgggacca
    32101 tgggactttt cgcattctct cgtgggagaa ggacaggata gaagtcttcc tcgaaggaca
    32161 acgactgcag ggaaaattcg tccttcttcg tttcaggaaa gcgggggaaa aagactggct
    32221 ggtactccgg gcgaagaact gatatctccc ggacgtctgg aaaaaaagga aattattctc
    32281 actttgcact tttaacggtc ttggaacccc gcaggattgc aatcgtgccc gtgcggacaa
    32341 gttccttgac accatactgg cggaggagct tttccagggc atcgatcttc tttgtgtcgc
    32401 cggcaaccga gaggacaact gaccggctcc cgacatcgat gatctgggcg cggaagatgc
    32461 ttgcaagctg catgatctct gccctgctgc ttcccggttc ggcattgacc ttgatgaggg
    32521 caagttccct ctcgacgcgg tcgttctcgg tgaggtccga gaccttgatg acgtcgatca
    32581 gcttgttcag ctgcttcatc acctgctcga tctgggcatc gtccccgatg cacacgatgg
    32641 tgatgcggga cattccgggc tcctcgcaga cccccactgc gaggctctcg atgttgaatc
    32701 cccggcggga aaagagtccc gtgacacgcg agaggacccc gggcttgttc tcgacaagaa
    32761 cgctcagggt atgcggtttc attcgcagtg tccccctatc atctcgttga tggccgcacc
    32821 ggcagggacc atggggaaga cgttctcctc gcgctcgatg cggaagtcga ggacaaacgg
    32881 cccgtctgtt tcgatggcag tgctgagtgc ggcccggacg tcggacgggt cctcgaccct
    32941 catcccatcg atcccgtagg cattggcaac cttgacgaag tctacgggcg ggagctcggt
    33001 ataggagtag cggcggtcat agaagagttc ctgccactgc cggaccatcc caaggaaccg
    33061 gttgttgaga atggcaacct tgacgggtat cctgtagtgg gaaacggtcc cgagttcctg
    33121 gatattcatc tggaagctcc cgtcacctgc gatatcgaag acaacctcgt ccgggcgcgc
    33181 gaaatgtgcc cccatggctg ccggaaaacc gtaccccatt gtcccgagcc ctcccgatgt
    33241 gatccaggtc cggggctttt tgaagccgaa gtactgggca gtccacatct ggttctgacc
    33301 gacctcgctc acgattatcc cttcgccctt caggagtgcc gaaagttcct caatgatgaa
    33361 ctggggccgc agggacccgt ctttggggta acgcatcggg tacttctcct tccatgcccg
    33421 gatccgtgcc agccattttt cgtagtcctt cttcttctgg atgcgggcga tcatctcctt
    33481 caggacggac tttgcatctc ccacgatcgg gacatccacc cgcttgttct tgccaatctc
    33541 tgcagggtcg atgtcaacgt ggatgatttt tgcctgggat gcaaaggtat cgagttttcc
    33601 tgtcacccga tcgtcgaacc ggacaccaat cgcgatgagg aggtccgatt ctgtaacggc
    33661 atagttcgcg taccgggtcc catgcatccc gagcatgccc aggttcaggg ggtggtcaca
    33721 gggaatggcc ccaagcccca tgagcgtcgt ggtgaccggg atcatcaaag attcggcaaa
    33781 ctggaggagc tcctccgctg cattggatga tatcacgccc ccgccgatgt acaggagagg
    33841 cctttccgcc tcgaggagca actccagggc cctgtcaatc tgccgggagt gcccccggta
    33901 cgtgggttgg taccccctca gggagacgtt ttccgattca gggtattcga agtctatctc
    33961 ctttgtgctg acatccttgg gcaggtcgat cagaaccggc ccgggacggc ccgtgcgtgc
    34021 aatgaagaag gcttccctca ccacgtgccc gagatcctcg gtcctcttga cgaggtagtt
    34081 atgcttcgtg atcggcatcg tgataccggt gatgtccgac tcctggaacg catcgttccc
    34141 aaggaggttt gtcgggacct gcccggtgag ggcaacgatc gggaccgagt ccatgtatgc
    34201 cgtcgctatc cccgtgacca ggttgcaggc ccccggaccg gaggtggcca ggcatacgcc
    34261 gaccctgccg ctggctcggg caaacccgtc agcggcatgg gcggctgcct gttcatgccg
    34321 tacaaggatg tgccgca
//
LOCUS       DAOOJU010000018        33473 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1427_length_33473_cov_16.058322, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000018 DAOOJU010000000
VERSION     DAOOJU010000018.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 33473)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 33473)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33473
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1427_length_33473_cov_16.058322"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..741)
                     /locus_tag="PK679_05850"
     CDS             complement(<1..741)
                     /locus_tag="PK679_05850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008983 - protein-glutamate
                     O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HPC55516.1"
                     /translation="MDEFQSLLQTIQRLFGIQCTNYKEDYIKRRLASRMNARRIATYR
                     EYQEYLLKHPEEHEPLKNALTINVTKFFRDPAVFECIRNEILTPMLRQQNRIRIWSAG
                     CSSGEEPYSYAMMLYDQTLIRKDIDWQVIATDIDDVILGKAREGVYDKSALEFVNERQ
                     LHRHFTRRADGKFEIKPHIREKVRFQHHDLMSGVPVQRGLDIVSCRNVTIYFSEPQKN
                     DLVRMFYQGLRPGGYYIMGMSEFLGREVE"
     gene            complement(759..1241)
                     /locus_tag="PK679_05855"
     CDS             complement(759..1241)
                     /locus_tag="PK679_05855"
                     /inference="COORDINATES: protein motif:HMM:NF013731.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HPC55517.1"
                     /translation="MPEILEFDLNGNSYAVDISYTREIVESLPITPIPRTPEYIAGMT
                     NIRGEITTLISLAMIIGQKAVPVSPSHKFIILVSEAAKGDKIGLIVDEVHSVYSVPDS
                     SIEYKTDGPSASRKSFIKGIIRLEEEKTGIGERKGTHKLILYLDIEKVLSHIFDLAKR
                     "
     gene            complement(1257..2846)
                     /locus_tag="PK679_05860"
     CDS             complement(1257..2846)
                     /locus_tag="PK679_05860"
                     /inference="COORDINATES: protein motif:HMM:NF012245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HPC55518.1"
                     /translation="MTSGGKKGTLADIQEAIRKRSSFAITLDPDKVDPACRHYAETIN
                     SLLMVTENLRLRTQVTFAENPFPILIFDRDWKILSANKAYSELSGIDRDHLKKMSAKS
                     FKILEQKGEGLKVAITSKKRSFGEVTVEMPSGVRILEQYGIPILDEKGEIQTVFVIYN
                     DITEKKALENRLRKSIDEIGDVLAGLAGGDLSRKAPRYENDPLEAVKRDLNTTIDRLT
                     ELVSNLVQTIEFLDRSLSDIITGTDEIARASQNVALTAQKNSEETKNQLRQLEKVSKD
                     ISELNADVEKIARASQEMALTSQKVLSAGEDAGKLGKEASEKMNLVQDLSRRVMDEMV
                     TLNSKTQEISNIVRVITDIANQTNLLALNAAIEAARAGEHGKGFAVVAEEVRNLAGGS
                     KNATKNIDTVIQDISRSSSQTVNSMKKAYDEIMTGIRSVEITIGALNQMAEGIRTTAE
                     SIGQISKATENQAAASTKVMNNVELIHNLIVHNERDAENLAALAEESSASIEEIASAT
                     SEIKQKMAECRRIVETFKIKN"
     gene            3056..3685
                     /locus_tag="PK679_05865"
     CDS             3056..3685
                     /locus_tag="PK679_05865"
                     /inference="COORDINATES: protein motif:HMM:NF015956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HPC55519.1"
                     /translation="MKTSAGEDILEAACLLLEKEKVMPTVRTVAGRLSEDEDRVRKEA
                     LELEKGGFLRLEEGDIIELSEKGREAGLRTIQKHTVLERFLSEILGMERAAASEEACI
                     LEHDISDETADRLEGFIAVPRGRGRRLQRGRRRLLTLADVPEGTDLRVVTVRCRGGYE
                     RLADLGILPGETIRVVHILNHKAVVVRVKGCDVALSPEIASSILVERLQ"
     gene            3682..5532
                     /gene="feoB"
                     /locus_tag="PK679_05870"
     CDS             3682..5532
                     /gene="feoB"
                     /locus_tag="PK679_05870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HPC55520.1"
                     /translation="MKIGLIGNPNVGKSLIFHQLTGIGVEVSNYPGTTVDLFSGTLCY
                     RKERIDLVDLPGIYSLEGKSPEEEIVRNFITGEEVEGLVAVLDATHLERNLYLLLQVA
                     EYKKPLVVVLNMMDEAEKRGIEIDREKLSSIIGTEVIPVTATQGKNVGEIIPAILFRS
                     RTPDITIPYDLHIEAAIRTLVSVHGISRVVALQALQGMVDDPGIAESAGTLAREIEEV
                     HRMSVQQIIAGNRHRCARVIAEKVIRKREEVTAGSLDTLLTSRVWGPVILCAVLAAIL
                     LSVFSIGSYLEAFLVGSFESLIVQPFLSLGLEPLPEQIGLAILLALQAGLGIAFPFIF
                     TFYIFISILEDSGYLTRAAFLADSTMHRLGMHGQGIIPLILGFGCNVPAIMGLRLLRT
                     RRERVIASFLVSMIPCSARTVIIAGIVAVFVGFGAALSIYVITFGLIILTGIVLSRIT
                     PGERYGMILELSPLRVPEPGNVLAKSWYRIREFLVIAMPLLVAASIVLGLLQYIGFFS
                     LFAELVAPFSETILGLPGYAASALLFGILRKEMALETLVILSGTADLASVLTAGQIYV
                     FAVVSVLFIPCISTMAVLARVVGARITFLVSLYTLILGVCIGALINILVV"
     gene            5542..6249
                     /locus_tag="PK679_05875"
     CDS             5542..6249
                     /locus_tag="PK679_05875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55521.1"
                     /translation="MYIYRTGIRLIDEKKGGLSPGSNILILAPSMSSGERLGYSVARP
                     APGEYALILSTVMRAVDLLDFFSESRIDPSRIGIIDAVSKLSTPDISDSTQVRYVSSP
                     SDLTGIGIKFSSMVESIFNGEFADSGDALFPPPVRFYIDSLTTLLMYRRLEVIYQFLH
                     VVTAKLKKMDAIGIYALNNESFDEKTLSLIKQLMNVVIEIKNEQHGDFLRVRGLPGVT
                     QEWVHFQITGEGLEVVI"
     gene            6246..7409
                     /locus_tag="PK679_05880"
     CDS             6246..7409
                     /locus_tag="PK679_05880"
                     /inference="COORDINATES: protein motif:HMM:NF012300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HPC55522.1"
                     /translation="MIRTGILGIDEMLGSGIPKGSRVIFSLEPGVDGSPFIFRILRTV
                     LSGGKNVLVIAPQATEKAFLSDFSQMMDASPGTGPGKILILDSCVRERINTRLKGSRS
                     RWKEWQKIIRETIGESGIEVLFVYFDLLYEDFGLEPALQLLPSGEEYRSLTTIVEHLN
                     LEGDSLISGFASGGYFDLIISVHSNISSVPFFNFFTLEYVSWSRMPRRSVPYTVTDGT
                     IRLYIPKIIVTGPPSSGKSTFVANASDSGLSVDRGDIDGFKTTVAMDLGWLHLRGFDI
                     TLFGTPGQPRFDPIIPQIIRNAMGIIMVIDATRPETLPRARELLTLAYSARIPVVVAV
                     NKADLPHTMDERQVRQSLKLRQAIPVLFISSLRRSDVHSVLESMIDHITRYSP"
     gene            7461..8210
                     /gene="dph5"
                     /locus_tag="PK679_05885"
     CDS             7461..8210
                     /gene="dph5"
                     /locus_tag="PK679_05885"
                     /EC_number="2.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004164 - diphthine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0017183 - peptidyl-diphthamide biosynthetic
                     process from peptidyl-histidine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine synthase"
                     /protein_id="HPC55523.1"
                     /translation="MLTFVGLGLHDHTDVSVKGLERIRNADIVFFEGYTSRLGGTSVK
                     EMEEFFEKKVTFVSRRDVEDDPGSILGPAGDKNVVFLTGGDPMVSTTHADLRIRAHRR
                     GIRTEIIHGASIVSAVCGLSGLQNYRFGKSCSLPFPEKNWYPLTPAEVIRTNLSMNLH
                     TLVYLDIRDDRCMTVHDAVSLLEEMSPRCGFSIPLYIGVARAGSPSPDVFCGDASKVL
                     AHDYGPPLHILIVPGPLHVMEKEYLELFGGL"
     gene            8207..8779
                     /locus_tag="PK679_05890"
     CDS             8207..8779
                     /locus_tag="PK679_05890"
                     /inference="COORDINATES: protein motif:HMM:NF015943.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF357 domain-containing protein"
                     /protein_id="HPC55524.1"
                     /translation="MISHPWGEEIARRLRATDIVPHPRTVYFTLAEELCSMAASYRDD
                     GEYFLSIGDTTNALAAFSYAMGWLDEASCLGLVTIGVSEKQWLFSHVPVPVTESGRLE
                     EKVERYGTMLSAALANVSCVTEGGTCIRGASDRILCACHVLKGFGNLFRSSGRPENAL
                     GSYSYAHAWLDAGVRAGLFCVVGRHELFAV"
     gene            8885..9916
                     /locus_tag="PK679_05895"
     CDS             8885..9916
                     /locus_tag="PK679_05895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HPC55525.1"
                     /translation="MKKTEKKWLWISLGFSLVVLAIILLFTVDSSTFTLLEKMNPFFI
                     ILALLIHLLALFFWSLRIWFMSRGLGYTVPFLHCINLVYANLLVAAITPSQAGGEPVR
                     VHELYKSGVKVGDATAIVITERILDGIVLGLGGAFYMFVLGSIWQTIGSVYSYFLYVS
                     WIFITGLVLLFLYSVKNPRILKNFLGGIARRIARFRGKDRADSYAQRIDKEVDNFHST
                     LALFLKQGKTGLLLGLVCTAAFWFLEAIIVSVILMGLSQPPILVESMIIQLVIAIIMM
                     IPLTPGGSGIAEVLFSTMYGIYIPHALIGIVVVLWRSILYYSNILLGFLGSLVIVRRE
                     AQNQDGDKP"
     gene            9946..10401
                     /locus_tag="PK679_05900"
     CDS             9946..10401
                     /locus_tag="PK679_05900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nuclease family protein"
                     /protein_id="HPC55526.1"
                     /translation="MEPVRCGVRGVYMAVSPLGASPAVIISLPGEEMCIPIYIGLWEA
                     ISIRNALKGEVPPRPLTHDLFVEFMKSFGIELREMVIDSIEDGVYYARLILVRDNHHL
                     SMDCRPSDGIALSLRCKADLFVDPEVVAGSSVSFSELSGLQDLDTYLGG"
     gene            complement(10403..10696)
                     /gene="hisE"
                     /locus_tag="PK679_05905"
     CDS             complement(10403..10696)
                     /gene="hisE"
                     /locus_tag="PK679_05905"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP diphosphatase"
                     /protein_id="HPC55527.1"
                     /translation="MERSDILLDLFEVIRDRVENPRPNSYVASLVGDPKGIDRVLEKV
                     GEETTEYILAVKNGRKDEITYEAADLVFHLMVSLKSAGVEWEEILRELASRRK"
     gene            complement(10683..11135)
                     /locus_tag="PK679_05910"
     CDS             complement(10683..11135)
                     /locus_tag="PK679_05910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusA-like transcription termination
                     signal-binding factor"
                     /protein_id="HPC55528.1"
                     /translation="MERTIGFKERRYIEELRILTRATAIDCIIDEKFERVIYVIRQGD
                     MGLAIGKKGENIRRLQNVLGKKVEMVEYSDDLFQFITHMFKPANVTGTKESAIPGTID
                     IIVKQKGDLGLAIGKGGTTIEKARILSRRFGGPEIGEIIVEEASGGTQ"
     gene            complement(11404..12144)
                     /locus_tag="PK679_05915"
     CDS             complement(11404..12144)
                     /locus_tag="PK679_05915"
                     /inference="COORDINATES: protein motif:HMM:NF016300.2"
                     /note="The SIMPL domain is named for its presence in mouse
                     protein SIMPL (signalling molecule that associates with
                     mouse pelle-like kinase). Bacterial member BP26, from
                     Brucella, was shown to assemble into a channel-like
                     structure, while YggE from E. coli has been associated
                     with resistance to oxidative stress; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HPC55529.1"
                     /translation="MNPQAITKGFSLLLVFVLVAAFLPGTVAAAENNERTISTSGSAE
                     TMVTPDRAHITVSVVTENANVQAAQSENARIMDSVSKSVESLGIGKKDLKTTGYSIYP
                     VYEDSKVPFGQKVKYYRVTNRLEVTIRDISRTGEVIDTAVRAGANQVDSIEFQVSEEL
                     EQSLREELLAKAVKKAYSDASIVAGAAGVTITGVKQITVAGSYPPRLYKSLASYAAGD
                     NAYEQAPTPIEPGEVKVTAEVSAVYLIG"
     gene            12313..13563
                     /locus_tag="PK679_05920"
     CDS             12313..13563
                     /locus_tag="PK679_05920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HPC55530.1"
                     /translation="MASTLVEKIFSRKCARDVRAGDVVMAPVDMAMIHDITGPLAVQK
                     FQEMGGKTVFDPGKIVLLFDHQVPADSLSAASNHVFLRKFAREQNIENLDGREGICHQ
                     VVMERGRAAPGEIIVGADSHTCMYGAAGAFATGIGSTDMGFVLKFGVLYFRVPETIRV
                     TVGGRFPGRVGPKDLILEIAGKIGADGATYQAIEFTGETFRTMDMPGRMTCCNMAVEM
                     GAKAGIVPPDEITWSYLASRRDIAPFSLASDDNASFSMEYSFDASRLSPRVAVPHNVD
                     QVVDVAKVAGTHIDQVFIGSCTNGRFEDLKEAADVLKDGTFHPGVRVIIIPSSRTEYL
                     KALKAGLIERFVSAGALVEAPCCGPCMGGAFGLLAPGEVSLSTSNRNFRGRQGSTDAF
                     VYLCSPATAAASAMKGEITDPREV"
     gene            13567..14061
                     /locus_tag="PK679_05925"
     CDS             13567..14061
                     /locus_tag="PK679_05925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HPC55531.1"
                     /translation="MRVWKFGDNIDTDAIIPGRYLVIYDPWALATHAFEGTRDEFAQN
                     AREGDIIVAGKNFGCGSSREHAPLALLGAGIRVIIARSFARIFYRNAINVGILPLVCP
                     EAGSIEDGAVVTINLDAGFIESGGRKMPIEAVPPFLKEIIDAGGLVGYARKLEKVKTC
                     TESQ"
     gene            14043..15158
                     /locus_tag="PK679_05930"
     CDS             14043..15158
                     /locus_tag="PK679_05930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate family dehydrogenase"
                     /protein_id="HPC55532.1"
                     /translation="MYRIAVIGGDGIGPEIVAEGKKVLEAAADRFSFDIQWEDFDIGA
                     ERYLETGELLTEEDLKELAGFRAIYFGAVGDERVKPGVLEKGILLSLRFFFDQYVNLR
                     PVRLLEGVTTPLAGKSPRDIDFVVVRENTEDFYVGVGGRVRGRDRATHEIVRTLYNIR
                     FGIDCESDADEMAYQIGIITREGAKRVITYACNLAGKRRKKLTSVDKANVMTDMYGLW
                     REVFSEVCGSYKDIETEFAFVDAVTMWFVKNPEAFDVVVTPNMFGDIITDLGAMIQGG
                     LGLAAGGNINPKGTSMFEPIHGSAPKYKGLNQANPMATIWAGSMLLDHIGETEAAEKV
                     LAAIGRSIRDGIVTKDMGGTSRTSDVGDYIAALVKKM"
     gene            complement(15178..15597)
                     /locus_tag="PK679_05935"
     CDS             complement(15178..15597)
                     /locus_tag="PK679_05935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55533.1"
                     /translation="MKRAGYLCRDGHEVLDGEGVPREVVFLFIHGARLCIPVEELTGV
                     IGRGTTGSVRRIKQNWMEYLGSEAGSISLSRSGKALNILLVNGDRFTLSLDSLQDVLS
                     YRERAAPIMEFHAGSGKRYPPNHLLTDFAGPLSPCTA"
     gene            complement(15683..16840)
                     /locus_tag="PK679_05940"
     CDS             complement(15683..16840)
                     /locus_tag="PK679_05940"
                     /inference="COORDINATES: protein motif:HMM:NF012375.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase component 1"
                     /protein_id="HPC55534.1"
                     /translation="MHDCSGPLWPCALTGAAAALAGIGGIGVVIHGSAGCYYYPSSVL
                     HLPLYCSSVTDRDIILGTEDALVRTIDAIRDKYDLVAVLCTCIPAITGEDIRGMLEQA
                     YSDSTRICVIDAAGFSGEYEDGFRSAIRAIDPPVSGGKTGVNIDGLSPFDPFRQGNFQ
                     EAQRLLGLAGTVAGAALPSGKYRYGQPLSPYTLHTNPDLTLDLGESLGCLVGLSRIED
                     AIRRIASFTGGADDLLEHDIPLAREKITAACDRFIKKFDPPHVALFGQCRTMQEIALM
                     LEEYLDADILVIGSRNPPVPGKYRVERARDYDTVVEILSRENPDLVLGSSFEKYACPG
                     AAFVGVTPPLRGTVRLHSRPLAGIEGALALFESVLNACMDHAKRRRDDPSP"
     gene            complement(16833..17867)
                     /locus_tag="PK679_05945"
     CDS             complement(16833..17867)
                     /locus_tag="PK679_05945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase component 1"
                     /protein_id="HPC55535.1"
                     /translation="MKTLHMSTPRDSGCTLTGALSVTTEIEGSLTIIHGPSGCAHHNF
                     SLLHALCAGRDDPRLPRVLSTDLAETDIIFGGEDALDAAIRRASGKNPSIICVLSTCV
                     TGAIGDDVEAVCRGFSGIPVISIPTAGFLGGGFHQGHVQALMSLSSLAEDDGKIPSAN
                     LVGEKTLETERDEHFNEVRRLLAAIGIPICTRFVCRTSVGEISRLSRGGCNILRDPSM
                     EGVGRFLEERFGTPFISSFPIGSRGTIQFLEEVGRVFSLDVSGAIAEEEARQARIFHE
                     FRSLRGKRVRFCDPFGNRTDSEVCREVASAAGMSVHPEGYPVPVPEPFPVGTEGIRRL
                     LYRWRRACRA"
     gene            complement(17836..18651)
                     /gene="cfbC"
                     /locus_tag="PK679_05950"
     CDS             complement(17836..18651)
                     /gene="cfbC"
                     /locus_tag="PK679_05950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni-sirohydrochlorin a,c-diamide reductive
                     cyclase ATP-dependent reductase subunit"
                     /protein_id="HPC55536.1"
                     /translation="MKQIALYGKGGIGKSTTAANLSAALACRGLDVMQIGCDPKRDST
                     RMLMQGRLIPTVMDLVRERGDTDITREDIVYEGFMGVRCVEAGGPEPGVGCAGRGIIA
                     TFQILERLGALHADVVVYDVLGDVVCGGFAMPMREGYAEEVYLVTSGELMSLYAANNI
                     CKAISRLSSRSRSTCRLAGVICNAKNLPREEELVAEFAKRIGSFLVLYIPRDQVVQQA
                     ELNKKTVVEYAPSSNQAAVYRELASRVMDNRRMDIPVPLGIEDLENLAYEYSP"
     gene            complement(18730..20187)
                     /locus_tag="PK679_05955"
     CDS             complement(18730..20187)
                     /locus_tag="PK679_05955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter TrkG"
                     /protein_id="HPC55537.1"
                     /translation="MGRIRYFSIVLGELGEMLTFISPLTLFALLVAIVFREWDLLLPL
                     AIVPLLFFGGGMILNSIPRHPGDVGFSTALCSVALLWLSFAVVSCIPFMIVLDIPFTD
                     ALFEAMAGWTGTGFSLLQDIDLLPRSLLFWRTYIQWLGGLAIISLSLTIAFRSNLDTM
                     APFRPESRSERIIPGIVANGKEIWAVYILLTVISVGIIIVARVPLWDALNLALSGIST
                     GGFIPVAGGVSSYNNTTLEFLLIPVMVMGSIPFSLFYMTYQNRKISFFSDEQVRILIY
                     FLCFGSLVVIADLLFIARYAPAEAVRQGLFMMTAVMSTTGFQNANLYLFPSVTLVFLT
                     MFMFVGGSSGSTAGGLHLSRIALGYRGIVWWFRRAFVRSTVLVPFRYQGRNVPIEVAE
                     PELSKSMLVIILSVITVFIATMVILQVHIISCDVTVLVFDIVSALSSCGVSAGYVGPT
                     MPLVSKWVFIFVMWIGRLDVIPVIVLFTGLLKGSD"
     gene            complement(20263..21237)
                     /locus_tag="PK679_05960"
     CDS             complement(20263..21237)
                     /locus_tag="PK679_05960"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: protein motif:HMM:NF005655.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HPC55538.1"
                     /translation="MGRVPPLLSALNASGSVYVIGVAGDSGSGKTTFASAIRHLLGDD
                     LVATLSLDDYHLYDREERKKRGITPLSPDANDFDRLERDVGRLRQGLSIQKMVYDHSN
                     GTIHGPFPFQPAKILILEGLHAFFTEKLRRLCDFTLFVDPDPDVKKEWKFKRDTGARG
                     YTEREVGDELTRRAMDYFAYVAPQREHATVVIGISFSRFGRNLGWEENIYRVTLDLSP
                     WDFYPASASLSFDFRGITSAHGRPFSFLFRPAGYQKRPAGTIELDGMLPCTCSESLVA
                     FLEETTGRDPGNLLQECRMLTPTDFTRLFVCGCIVTHRLSIADNGTGS"
     gene            complement(21329..22516)
                     /locus_tag="PK679_05965"
     CDS             complement(21329..22516)
                     /locus_tag="PK679_05965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HPC55539.1"
                     /translation="MSVREIVPGIYAVGAPDFDRRLFDSLIPLPHGTTYNSYLVKGAK
                     KTALIDTVDPSKELDLVTNLVKARVDTIDYIVINHVEQDHSGSLPMIAELFPKASIVV
                     NEKSKDLVTRVLDVDPARCMEIKDKDTLDLGGKTLQFFITPWVHWPETMVTYAVEDRV
                     LFSCDLFGTHYAESSLFVTDEREVYISAKRYYAEIMMPFRRNIADHMEKLKDIPVSII
                     APSHGPVHSRPGFILDAYRDWISDTVKDEVVIPYVSMHGSTEKMVNHLCEALIERGIR
                     VKPFNLTVTDIGELAMALVDAATVVIGTPTVLFGPHPQAVYAAYLFNMLKPKTRFLSV
                     IGSYGWGGNTIEALKGMLTRTKPELLEPVYIRGAPGASDQKKIEELADTIVGKHREIG
                     IHQ"
     gene            complement(22529..22687)
                     /locus_tag="PK679_05970"
     CDS             complement(22529..22687)
                     /locus_tag="PK679_05970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011832552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HPC55540.1"
                     /translation="MDSYMCTICGHVYSPEKGEPDMGIPPGIDFSQLPGDWKCPVCKA
                     APALFRRL"
     gene            22848..23927
                     /locus_tag="PK679_05975"
     CDS             22848..23927
                     /locus_tag="PK679_05975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHMP kinase"
                     /protein_id="HPC55541.1"
                     /translation="MTIMKIRGGDLDLVEYEFVTFRPGEQVKTAGIVCSRPVVPFSGT
                     VTVRAPARIHLTVLDMNRFSPSRPGGGGVGFAIQLYCTVSVSCTEKEITIDYNRPAII
                     RHFIEVFRKISRYTGGFAVSAQDHQHQHVGLGSTSTIMIALAHALNTAVGSPFSNDQL
                     RKMIGYNYVEETVEGNVAFGFETGVGPAASTYGGMAIMGDDLTLIYHHPFAMGKDVYV
                     VIPPSDISSAGTKEFDLLMNKARVLDYRDRELKAYLIMMDLIPALEKGDLSKMGDIIW
                     EFDFRGSKRAEVEHHSFAIYHYMSRLREAGLEFVGMSSVGPSISIITGRPRSEVEKIV
                     RDLGLSVAVTTAVDNEGLKVSVSGK"
     gene            24133..24474
                     /locus_tag="PK679_05980"
     CDS             24133..24474
                     /locus_tag="PK679_05980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HPC55542.1"
                     /translation="MHEFGIAYDIYATARKAALERNARDVREVHVEFGEMAMVNPEQI
                     AFLYDTLIEDDALMRGSRLTWSVVPPLTRCTCGYEGSERFVCPRCGKFPELVRGLEVM
                     VTHMEIEVDDE"
     gene            24471..25466
                     /gene="hypE"
                     /locus_tag="PK679_05985"
     CDS             24471..25466
                     /gene="hypE"
                     /locus_tag="PK679_05985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="HPC55543.1"
                     /translation="MKVTLMHGAGGEVMGEVLQILTRMEHRNAGGIGLESLDDGAVIP
                     LGGQNIVFTTDSHVVRPVFFPGGDIGRLAVCGTVNDLAMMGGRPVALSCSMVIEEGFD
                     SKDLERIVASMDAALGECGASIVTGDTKVLEKGALDGIVVNTAGIGIAEKVIRDCTLQ
                     PGDAIIVNGTLGDHGLTIMAERAGLSLGSQLKSDVAPLWNLVAGALAAGDIHAMKDPT
                     RGGFASAINEMARKSRVGVRIREELIPLKKSVRSASEMLGIDPLQVANEGKVVMGVAG
                     KDAEAVLAALRSHPYGKDAAIIGTVVAGSGVILETEIGGERFIEPPIGDPVPRVC"
     gene            complement(25463..26041)
                     /locus_tag="PK679_05990"
     CDS             complement(25463..26041)
                     /locus_tag="PK679_05990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF447 family protein"
                     /protein_id="HPC55544.1"
                     /translation="MGLLREGINEVIATTKDNAAPMGVILRNGSHTMVVFHGSHTSEN
                     ISRYGWVVANIIHDPVLYVKTAFSDLEPRFFSRETIGDLVVQRLSSAEAWVAFRAEVT
                     RDTGEALVVNLTPLHEEVLSCTIHPVNRGFSSVIEATIHATRYVRREDSQLEQLISHH
                     ASIVRRCGGPREKEALALLEDFLSRKSGFRMV"
     gene            complement(26029..26844)
                     /locus_tag="PK679_05995"
     CDS             complement(26029..26844)
                     /locus_tag="PK679_05995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase"
                     /protein_id="HPC55545.1"
                     /translation="MQNLTRAQRAQLAMVLEVSAFPKPGNVDRCHDFPTTRLEHFLAS
                     AIMAGPALEAAERGGRGLGSLIHEAVALTGGYSGGNTHFGAFILLMPLVAGDGIEGAM
                     RLIGETTVEDSIEFYRAFGKTSVRVIPGHELDVNDPSSLQEIRDRGMTLYDLMLYSAP
                     RDMVAREWVSVFQMTRRGADLLHAAGCGREGIVQAFLSLLALEPDTFIVKKHGPEVAG
                     MTMRRAREVLEGVRDLQEFDQECIQKGINPGSIADIIVASIYTALGEGWEWDC"
     gene            complement(26795..27958)
                     /locus_tag="PK679_06000"
     CDS             complement(26795..27958)
                     /locus_tag="PK679_06000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 9 domain-containing
                     protein"
                     /protein_id="HPC55546.1"
                     /translation="MMRSFERYNLLLNGQVVRTPLALSAMAGIVDADYALARASHVGV
                     AFLGGFSIDAPTMEASRAMERSGRREFLFGDPVEELAGQVQRLEGSGLVVGLNLRGSS
                     PESFAAIASHLGDQAIYEIDAHCRQEPMVEARSGEYLLSHTDLLAEEIRALKREDVSV
                     SVKIRAGVSPDDRLLARKIWKAGADIIHVDLMDYDYQKVRQMRNSCPLVLIANNSMNT
                     FDRVRDMFSHGADLVSLARNADVRTLAGLDAAIERLTDEQGWYNAPKQLCRGGDIRAL
                     TFCCMPVKNCPLLPMLDRLGLSREEYLSFKQKAVAGTPLEPGAQTCFGSLAWCCKVSS
                     PCMFRDMTLAQSGLSRQEYMRQKKQLADKIIQHLFSRDAEPHTCTTRPARDGS"
     gene            28228..28629
                     /gene="cfbA"
                     /locus_tag="PK679_06005"
     CDS             28228..28629
                     /gene="cfbA"
                     /locus_tag="PK679_06005"
                     /EC_number="4.99.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin nickelochelatase"
                     /protein_id="HPC55547.1"
                     /translation="MGKKGLLLVGHGSKLPYNKELVESTARLIGKRCPEYVIRCGFMN
                     INSPTIREALEQFRKDAIDVIIVVPVFLAKGVHILEDIPGEIGLAKGQVKGEFALNGK
                     TIPLLYADPIGSDPLLADLMIKNAERALREL"
     gene            28639..29847
                     /gene="cfbE"
                     /locus_tag="PK679_06010"
     CDS             28639..29847
                     /gene="cfbE"
                     /locus_tag="PK679_06010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F430 synthase"
                     /protein_id="HPC55548.1"
                     /translation="MRILVLDTIHGGRTIALALRERGHTVDMVDIYRGKEGISPSDAR
                     SGDYEMIIAPVHLDPGHPLLRDLPAPLVSHHEAVRWIIGKQAPARFIEVTGARGKTTV
                     ASAMAHVMQGPGILHTSRATVRLPENETMGRLGITPASLIAPAHSAYSQDRWLIGEVS
                     LGFVGAGNLGILSSAGTYTFGAGKRDALSEKLRSGNRLPLIIVPPGFSRSGNRLPADE
                     VALSEGSMCRYEWDGITGRYENPLLVTKAYRDPLLLATAAACVLGIDPSPLAGFKPLE
                     GRKTVSWVGRTLVMDDSNSGTCAGTARDAIRLARARAGRPSPLVLVIGKEAGAICEGF
                     PPDEVASVISTESPDHVILVGDYDLDEVCRRWKGKGSVLQARTLEEGRTRAMQFPDGS
                     IVVLAVKTWR"
     gene            29853..30917
                     /gene="cfbD"
                     /locus_tag="PK679_06015"
     CDS             29853..30917
                     /gene="cfbD"
                     /locus_tag="PK679_06015"
                     /EC_number="6.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ni-sirohydrochlorin a,c-diamide reductive
                     cyclase catalytic subunit"
                     /protein_id="HPC55549.1"
                     /translation="MKYMQPRPSSIVAALYTARDLGVDVSVLHGPSGCSFKHARLLEE
                     DGMRVLTTSLADHEFIFGGQQPLEAVLQYAERTFSPRRMAVIGTCVSMIIGEDLQAAI
                     RNSGIVTPTIAIEIHAGYPENIAGVIATLEPAAAQGWISQEELERQKFLLGKANEVER
                     LRGAASRPYIEPSRGDLKHVAAERLLSLVDSGKRGVAIMNAKKETAYMFADELLALHD
                     ARPAADITFVANLEERGLPKVREDARRIRTEIEGRGLDMQLCGALDEYGANGEALGEV
                     IRSISPEFAFIVGVPHAIPPSALQGIECISVTNGPRQVEPLREQGHRIVVVEVDLHPR
                     TLGVKNIVESELGAVIRSMA"
     gene            30914..32296
                     /gene="cfbB"
                     /locus_tag="PK679_06020"
     CDS             30914..32296
                     /gene="cfbB"
                     /locus_tag="PK679_06020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni-sirohydrochlorin a,c-diamide synthase"
                     /protein_id="HPC55550.1"
                     /translation="MKALMIAGDRSGSGKTSITLAIASVLSRTMAVQTFKVGMDYIDP
                     SYLSAVTGRPCRNLDTYVMSPDQVLSVFANGCRGADVALIEGVRGLYEGAEALDDSGS
                     SASVARILEVPVVLVVNARSITRSAAAIVRGFQSFDPSIRIAGVILNNVAGEKHAEKA
                     GKAVEHYCGVPVLGTVPRDPELELGMRHLGLVPFREGQEVSGFREKIGTITEVVRQSV
                     DTGSLLKIAREVCLPEGEAPWFSRTKKEHTRIGIAYDHVFNFYYADLFDILKAQGSTI
                     VFFSPASGDLPDADGYIIGGGYPEMHAAALAENQNMLEEIRERSREGTPLYAECGGLM
                     YLTRELVLKEGWQGKKSEERYSMSGVFPGKTVMPARRVVAYVSGESSPESPMGASRFR
                     GHEFHYSAVLLPHDTRFVYRLSRGQGIRDGQDGALVRKTLGSFSHLHPVGSHAMFSRF
                     LETCRDSREA"
     gene            32344..33210
                     /gene="ilvE"
                     /locus_tag="PK679_06025"
     CDS             32344..33210
                     /gene="ilvE"
                     /locus_tag="PK679_06025"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HPC55551.1"
                     /translation="MFVYIDGTMYPKEEAKISVFDHGLLYGDGVFEGIRMYNGRIFRL
                     PEHIDRLYDSAKAIDLCIPLTKDQMTAAIIETVRKNGFKNAYIRPIVTRGVGDLGLCP
                     TKCPKPTVIIIATEWGAMYGDLYEKGLRAVTVSIRRNPCCTLPPNIKSLNYLNNILAK
                     IEANCKGGDEAIIFDMQGHISEGSGDNIFIIKNGVIYTPPTLNNLRGITRMVVLENAK
                     ALGIPVVETNLGYFDLYTADEVFVTGTAAEVAPIVHIDGRDIGSGRPGPITRQLMAAF
                     RAATEREGTPVS"
     gene            33284..33358
                     /locus_tag="PK679_06030"
     tRNA            33284..33358
                     /locus_tag="PK679_06030"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33320..33322,aa:Glu,seq:ttc)
BASE COUNT         7128 a         9381 c         9576 g         7388 t
ORIGIN      
        1 ttcgacttca cgccccagga attccgacat tcccatgatg taatacccgc ccggacggag
       61 tccctggtaa aacatgcgga cgaggtcatt cttctggggt tcggaaaagt agatcgtgac
      121 gttgcgacac gatacgatat caaggccacg ctgcacgggg acacccgaca tcaggtcatg
      181 gtgctggaac cgcacttttt ccctgatgtg cggtttgatc tcgaattttc cgtcggccct
      241 ccgggtaaag tggcggtgaa gctgccgttc gttgacgaac tcgagcgctg acttgtcgta
      301 cacaccttcc ctcgctttcc cgaggatgac atcatcgata tcggttgcaa tgacctgcca
      361 gtcaatgtct ttccggatga gtgtctggtc atagagcatc atggcatacg agtaaggttc
      421 ttcacccgac gagcaccctg cactccatat ccggatcctg ttctgctggc ggagcatggg
      481 ggtgagaatc tcgttcctga tgcactcaaa gacggcaggg tcccggaaaa acttggtgac
      541 gttgatggtg agggcattct tgaggggttc gtgttcttcg gggtgcttga gaagatactc
      601 ctggtattcc cggtatgttg ctatccgcct tgcattcatc cgggacgcca ggcgacgctt
      661 gatgtaatct tccttgtagt tggtacactg gataccaaaa aggcgctgga ttgtctggag
      721 gagactctga aattcatcca tgggtagtat ccggcaactt accgcttggc aaggtcaaag
      781 atatgggata gtaccttttc aatatcgaga tataaaataa gcttatgggt acccttcctc
      841 tcgccaatcc cggttttttc ctcctcgagc cgtatgatcc cttttatgaa ggatttccgg
      901 gacgctgacg ggccatcggt tttgtactcg atgctcgagt cgggaacaga atagacgctg
      961 tgtacctcgt cgacaatgag gccgatcttg tcaccttttg cagcttcgga tacgaggatg
     1021 atgaacttgt gcgatggtga caccggcaca gccttctgcc cgatgatcat ggcgagggat
     1081 atgagggttg ttatctctcc ccggatgttc gtcatcccgg caatgtattc cggggtcctg
     1141 ggaatcggag tgatggggag agactccact atctcgcggg tataactgat gtcaaccgca
     1201 taggagtttc cgttcaggtc aaattccagg atctcgggca tgacgtgcgt atcctttcag
     1261 ttttttatct tgaaggtttc cacgatcctc cggcactccg ccatcttctg cttgatctca
     1321 ctcgttgcac tcgcaatctc ctctatcgac gcactgctct cttcggccag ggctgcaagg
     1381 ttctcggcgt ccctctcgtt gtgaacgatg aggttgtgga tgagctcgac gttgttcatg
     1441 actttagtgc tcgcggcagc ctggttctcc gtggccttcg atatctgccc gatactctcg
     1501 gcagtcgtcc ttatcccttc tgccatctgg ttcagtgccc cgatcgtgat ctccacgctc
     1561 cggatgccgg tcatgatctc gtcataggcc tttttcatcg agttgacggt ctggctgctc
     1621 gagcgtgaga tgtcctgaat cacggtatcg atgttcttcg tcgcattctt ggatccccct
     1681 gcgaggttcc tgacctcctc tgcaacgact gcaaaaccct tcccgtgttc tccggcccgt
     1741 gcagcctcga ttgcggcatt cagggccagg aggttcgtct ggttggcaat atcggtgatg
     1801 accctgacga tgttgctgat ctcctgcgtt ttggaattca gggtcaccat ctcgtccatg
     1861 acgcgccggg agagatcctg aacaaggttc atcttttcag atgcttcttt cccgagtttt
     1921 cccgcatctt cgcctgcaga aaggactttc tgggacgtca atgccatttc ctgcgatgcc
     1981 cgggcgatct tctccacgtc ggcatttagc tcggagatgt cttttgatac tttctcgagt
     2041 tgcctcaact ggttcttcgt ctcctccgag ttcttctgtg ccgtaagggc gacattctgc
     2101 gatgcccggg cgatctcgtc agttcctgtg atgatgtccg agagcgatct gtccaggaac
     2161 tcgattgtct gtaccagatt tgatacgagt tcggtcagtc tgtcgattgt cgtgttgagg
     2221 tcccgcttga cggcctccag ggggtcattc tcataacggg gtgctttcct ggaaagatcc
     2281 ccgcccgcga ggcctgctaa gacgtcccca atctcgtcaa tactcttcct gagacggttc
     2341 tcgagggctt ttttctctgt aatatcgttg tagatgacaa agaccgtctg gatttctcct
     2401 ttctcgtcga ggatggggat gccgtactgt tccagtatcc tgacgccact tggcatctct
     2461 actgtgacct cgccgaagga cctttttttc gacgtaattg cgaccttgag cccttctcct
     2521 ttctgttcga gaatcttgaa gctcttggcg ctcatcttct tgagatggtc ccggtctatc
     2581 cccgagagct cgctgtatgc cttgtttgca gagaggatct tccagtcccg gtcgaagatc
     2641 aggatgggaa acgggttctc tgcaaaggtg acctgggtcc ggagtcgcag gttctccgtg
     2701 accatcagga gggagttgat agtctctgca tagtgccggc aggcaggatc caccttgtcc
     2761 gggtccaggg tgatcgcaaa agaggatctc ttcctgatgg cctcctggat atcagcaagg
     2821 gtgccttttt ttcctccgct tgtcatttta tgatagtgtc tacaaagtag tatattaatt
     2881 cattgctaat aatcatcaaa aatgaaaaac attcccagtc attaaatggc agagggtact
     2941 tctctccccg gttattctcc tgatgaccgg aactggtctt aagaccaaat ctcaggagta
     3001 actcccctgt atttatccaa attctcaaat aatttcggga acaattattc ctgcgatgaa
     3061 gacttcggcc ggggaagata tcctcgaggc tgcctgcctc cttctggaga aggaaaaagt
     3121 tatgccgacg gtaaggactg tcgcaggccg gctctccgag gacgaggaca gggtccggaa
     3181 agaggccctg gaacttgaga aagggggatt tctccggctg gaggagggag acatcatcga
     3241 actctctgaa aagggcaggg aggcggggtt gcggacgata cagaaacaca cggtccttga
     3301 gcgtttcctc tcggaaatcc ttggcatgga acgtgctgcc gcatcggaag aggcctgcat
     3361 cctcgagcac gatatttcgg acgagacggc agacaggctc gagggtttta ttgcagtccc
     3421 ccggggacgt ggccggaggc tgcagcgggg acgccggaga ttattaaccc ttgccgatgt
     3481 tccggaaggc acggatctca gggttgtcac cgtccggtgc cggggaggat atgaacggct
     3541 ggctgacctt gggattcttc cgggagagac catccgggtt gtgcatattc tcaaccacaa
     3601 agccgtcgtc gttcgcgtca agggctgtga cgtcgcgttg agccccgaaa tcgcctcttc
     3661 catcctcgtg gagaggctgc aatgaaaatc gggctcatcg ggaaccccaa cgtggggaag
     3721 tcgctcattt ttcaccagct gacagggatc ggcgtcgagg tcagcaatta cccgggaaca
     3781 acggtggacc tcttctcggg gacactctgt tacaggaagg agagaatcga tctggtggac
     3841 cttcccggga tttattccct tgaggggaag tctcccgaag aagagatcgt caggaatttc
     3901 ataacaggag aggaagtcga gggtctcgtc gcggtccttg atgcaaccca tctcgagcga
     3961 aacctctacc tcctcctgca ggttgccgag tacaaaaaac ccctcgttgt ggtcctgaac
     4021 atgatggacg aggctgaaaa acgcggtatc gagatcgata gggagaaact ctcgtccatc
     4081 atcggaaccg aggtcatccc tgtcacggca acacagggta aaaatgtcgg ggagattatt
     4141 ccggcaatcc tctttcgatc caggacgccg gacatcacca tcccctacga cctccacatc
     4201 gaggctgcta tacgaacact cgtctctgtt cacgggatca gcagggttgt cgctctccag
     4261 gcactccagg gtatggtcga tgatcccggt atcgccgaat cagcgggcac tcttgcaagg
     4321 gagattgagg aggtgcaccg gatgtctgtc cagcagatca tcgccggaaa ccgccaccgc
     4381 tgtgcacgcg tgattgcaga aaaggtaatc cggaagagag aagaggtcac tgcgggttcc
     4441 ctcgataccc tgctgacatc gcgggtatgg ggccccgtca tcctttgtgc tgttctcgca
     4501 gccatccttc tctccgtttt ctccatcggt tcgtacctcg aggcattcct cgtcgggtcc
     4561 tttgagtccc tcatcgtcca gccattcctc tcgcttggtc ttgaacccct gcccgaacag
     4621 atcggtcttg caatcctgct cgcactccag gccgggcttg gaattgcatt tcccttcatc
     4681 ttcacgttct acatcttcat atcgatcctg gaagactccg gatacctgac gcgggcagca
     4741 ttcctcgcag acagtaccat gcaccgcctc ggaatgcacg ggcagggtat cattcccctc
     4801 attctcgggt ttggatgtaa cgtcccggca atcatgggtc tccgtctcct ccgcacccgg
     4861 cgggagaggg tcattgcatc gttcctcgtc agcatgatcc cctgctctgc acggaccgtc
     4921 atcattgccg gaatcgtcgc ggtttttgtc ggtttcgggg ccgcgttgag tatctacgtg
     4981 atcacgttcg gcttaatcat cctgacggga atcgtcctgt cccggattac gccgggggaa
     5041 cgctacggga tgatcctcga actgtcgcct ctccgtgtgc cggaaccggg caacgtcctt
     5101 gcaaaatcct ggtacaggat aagggaattt ctggtcatcg caatgccact cctcgttgct
     5161 gcaagcattg tccttggtct cctgcagtat atcgggttct tttccctctt tgcagaactt
     5221 gtcgctcctt tttcagaaac aatcctcggg ctgcccgggt acgcggcaag cgcccttctg
     5281 tttggaattc tgcggaagga gatggcgctc gagacacttg tcatcttatc aggaacggct
     5341 gaccttgcat ccgtcctgac tgcaggccag atctatgttt ttgcagtggt cagcgtactc
     5401 ttcatcccct gcatatccac gatggcagtc cttgcaaggg tcgtgggagc ccggattacg
     5461 ttccttgtct ccctgtatac gttaattctc ggcgtttgca tcggagcgct tataaacatt
     5521 cttgtggtat gataatgagg aatgtatatt tatagaaccg ggattcgtct tatcgacgag
     5581 aagaaagggg ggctttcccc gggatcgaac attctcattc ttgctccgtc catgagcagc
     5641 ggtgagcggc tggggtactc cgttgcccgg ccggccccgg gggaatatgc gctcatcctc
     5701 tcgactgtca tgcgggcagt cgatctcctc gatttctttt cagagtcccg catcgaccct
     5761 tcgagaatcg ggataatcga tgccgtgagc aaactctcga cacccgatat ctccgactcg
     5821 acccaggtcc ggtacgtatc gagccccagt gacctgacgg ggattggaat caagttctcg
     5881 tcaatggtgg agagtatctt caacggcgag tttgcagact ccggtgatgc tctctttccg
     5941 cccccggtac ggttttatat cgactcgctg accacgctcc tcatgtacag gaggctggag
     6001 gtcatctacc agttcctcca tgtcgtaacc gccaagctga agaagatgga tgccatcggg
     6061 atatatgcac tcaacaacga atcattcgat gaaaaaacgc tctccctgat caagcagctc
     6121 atgaacgtcg taatagagat aaagaacgaa caacacgggg acttcctcag ggtaagaggc
     6181 ctcccgggag taacgcagga atgggttcac ttccagataa ccggggaagg actggaggtg
     6241 gtcatatgat ccgaacggga attcttggaa tagacgagat gctcggatcc ggcattccga
     6301 aagggtcgag ggtgatcttt tcactggagc cgggtgtcga cgggagcccc ttcatcttcc
     6361 ggattctccg gaccgtcctt tcaggcggaa agaacgtact ggtcattgca ccccaggcga
     6421 ctgaaaaagc attcctttcg gacttttccc agatgatgga tgccagtccc ggcacgggac
     6481 cggggaagat tctcatcctc gacagttgcg ttcgcgagcg tatcaatacg cgcctgaaag
     6541 gatcacggtc ccgctggaaa gaatggcaga agattatccg ggagacgatc ggagagagtg
     6601 gtatcgaagt tctctttgtt tacttcgatc tcctctacga ggactttggg ctggaacctg
     6661 ccctgcagct cctcccctcc ggggaggaat acaggagcct gaccacgatc gtcgagcatc
     6721 tcaacctcga gggagacagc ctcatatccg gattcgcatc agggggatac ttcgatttga
     6781 ttatctccgt gcactccaac atcagttcgg ttcctttctt caatttcttc acgctggaat
     6841 acgtctcgtg gagcaggatg ccccggcgtt ccgttcccta cacggtgact gacgggacca
     6901 tccgcctgta tatcccgaag atcatcgtga ccgggccgcc ttcctccggg aaatcgacct
     6961 tcgttgccaa tgcatcggat agtggtctct ctgtcgatcg gggagatatc gatggtttca
     7021 aaacgacggt tgccatggac ctcggctggc tgcacctgag gggttttgat atcacgctgt
     7081 tcgggacccc gggacagccc aggttcgacc cgatcatacc ccagatcatc aggaatgcga
     7141 tgggaatcat catggtcatc gacgcaacgc ggcccgagac ccttccacgg gcaagggagc
     7201 tcctgacgct tgcctattcc gcacggattc ctgtcgtggt tgctgtaaac aaggcagacc
     7261 ttccccacac gatggacgag aggcaggttc ggcagagcct gaaattgagg caagccatcc
     7321 cggtcttatt catcagttcc ctccggcgat ccgacgtcca ttcggtgctc gagtccatga
     7381 tcgaccatat cacccgctat tccccctgac agacaggcgt accgggggaa caacaccgta
     7441 cctgcgagga gaaagaaagg atgctcactt tcgttgggct cggcctccat gatcacacgg
     7501 atgtatcggt aaagggcctt gagagaatcc ggaatgccga catcgtcttt ttcgaggggt
     7561 atacctcgag gcttggaggg acctcggtta aggagatgga ggagtttttt gaaaagaagg
     7621 tgacttttgt cagccggagg gatgtcgaag acgatcccgg gtcaatcctt ggcccagccg
     7681 gggataagaa tgttgtcttt ctgaccggcg gggatcccat ggtctcaacg acccacgcgg
     7741 acctccgtat cagggcacac cgccgtggta tccggacaga aatcattcac ggggcctcca
     7801 tcgtcagtgc agtctgcggg ctttcaggtc tccagaatta ccgtttcggc aagtcgtgtt
     7861 ccctcccttt tcctgaaaag aactggtacc ccctgacacc cgcggaggtt atccggacca
     7921 atctctccat gaacctgcat accctcgttt acctcgatat ccgggatgac aggtgcatga
     7981 ccgtgcacga tgctgtctcc ctcctcgagg agatgtcccc aagatgcggt ttttccattc
     8041 cgctttacat cggtgtggca cgggcaggat cgccttcgcc cgacgtgttc tgtggggacg
     8101 ccagtaaagt tcttgcccac gattacggtc cccccctcca tatcctgatc gtccccggtc
     8161 ccctccacgt catggaaaag gagtacctcg aattgttcgg aggtctatga tatcccaccc
     8221 ctggggcgaa gagattgcac gacggctccg ggccacggat atcgttccgc acccccggac
     8281 cgtgtatttt actcttgcag aagagttgtg ctccatggct gcctcctaca gggacgatgg
     8341 tgaatatttc ctttccattg gagataccac aaacgccctt gccgcttttt cgtatgccat
     8401 gggatggttg gacgaggcgt cctgccttgg actcgtgacc atcggggtga gtgaaaaaca
     8461 gtggttgttt tcgcatgtcc ctgttcccgt aaccgaatcc gggcgacttg aggaaaaggt
     8521 ggaacggtat ggcaccatgc tttccgcggc gcttgcgaac gtttcatgcg tcacggaggg
     8581 agggacatgt atccgggggg cctctgaccg gattctctgt gcatgccatg tactcaaagg
     8641 gttcgggaat ctcttccgat cgtccggcag gcctgaaaat gccctcggat cgtacagcta
     8701 tgcccatgcg tggctcgatg caggtgtccg cgcagggctc ttttgtgtcg tgggaaggca
     8761 tgagctcttt gcggtataat cgggctgttt tgaacctttt accgccattt acaaatatta
     8821 atgcagtaca acagctctac ctgtttcatt tcacatcccg ggggattttt cccgcgtgag
     8881 gaccatgaag aagactgaga aaaagtggtt gtggatatcc cttgggttct ccctcgtcgt
     8941 ccttgccatc atcctccttt ttaccgttga ttcatccacg ttcacgctcc tggaaaagat
     9001 gaatcccttt ttcatcatcc ttgcactcct catccacctc ctcgccctct tcttctggtc
     9061 gctccggata tggttcatga gccggggcct cgggtacacg gtgccgttcc tccattgcat
     9121 caacctcgtc tatgcgaacc tcctcgttgc tgcgataacc ccctcgcagg caggcggtga
     9181 acccgtccgg gtacacgagc tctataaatc gggggtaaaa gtcggggatg caacggccat
     9241 cgtgatcacg gaacgcatcc tggacgggat cgtccttggt ctcggcgggg cattttacat
     9301 gttcgtcctt ggcagcatat ggcagacaat cgggtccgtg tacagttatt tcctctacgt
     9361 atcatggata ttcatcaccg gactcgttct cctctttctc tattccgtga aaaatccacg
     9421 aatcctgaag aatttcctgg gcggaattgc ccggcgcatc gcacggttcc ggggtaaaga
     9481 tcgggctgac tcctatgcgc agcgcatcga taaggaggtg gacaatttcc actcgacgct
     9541 tgccctgttc cttaaacagg gaaagacagg gctgctgctc ggtcttgtct gcaccgcggc
     9601 cttctggttc ctcgaggcaa tcatcgtctc cgtgatactc atgggcctct cccagcctcc
     9661 catcctggtc gagtccatga tcatccagct ggtcattgca atcatcatga tgatcccgct
     9721 cacacccgga gggtcaggga tagccgaagt cctcttctcc accatgtacg gtatctatat
     9781 cccgcatgcc ctcatcggga tcgttgtcgt gttgtggcgc agcatcctct actattccaa
     9841 tattctgctt ggattcctcg ggagcctcgt catcgtccgg cgggaggccc aaaaccagga
     9901 tggtgacaaa ccttaaagcc acgaccgggt aattccttct cacagatgga accggttcgc
     9961 tgcggtgtca ggggagtcta catggcagtg agtcccctcg gggcctcgcc tgcagtcatc
    10021 atctcgctcc ccggagagga gatgtgcatc ccgatttaca tcggcctgtg ggaagcaatt
    10081 tccatccgga acgccctcaa gggagaggtc ccgccgcgac cactcacgca cgacctcttt
    10141 gtcgaattca tgaagtcctt tgggatcgag cttcgcgaga tggtcatcga ctctatcgag
    10201 gacggagtat actacgcccg cctcatcctc gtccgtgaca accaccacct gagcatggac
    10261 tgccggccaa gcgacgggat tgcgctctcg ctccgctgca aagcagacct cttcgtggac
    10321 ccggaagtcg tggccggctc ttccgtcagc ttttcggaac tttccggcct gcaggacctg
    10381 gatacatacc tgggaggctg agtcatttcc tccgggaagc gagttcccgg aggatttctt
    10441 cccattcgac accggcagat tttaagctga ccatgaggtg gaagacgaga tctgcggctt
    10501 cgtaggtgat ctcatctttc ctgccgttct tgacggccag gatatactcg gttgtctctt
    10561 cccccacctt ttcaagcacc ctgtcaatac ctttggggtc tcccacgagg gatgcaacgt
    10621 atgagtttgg tcttggattc tccacgcggt ccctgataac ctcgaaaagg tcgaggagga
    10681 tgtcactgcg ttccacctga cgcctcctcc acgatgatct caccgatctc cggcccgccg
    10741 aaccggcgtg agagaattct tgccttctcg atcgtggtcc ctcccttgcc gatggcaaga
    10801 ccgaggtctc ccttctgttt cacgatgata tcgatagtcc cgggaattgc agattccttc
    10861 gttccggtca cattggcagg tttgaacatg tgggtgatga actggaagag gtcatcggaa
    10921 tactcgacca tctccacttt ttttccgagg acattctgga gacggcggat attctccccc
    10981 tttttgccta tcgcaagccc catgtctccc tgcctgatga cataaatgac acgttcgaat
    11041 ttttcgtcta tgatgcagtc tattgcggtg gctcttgtca gtatccgtaa ttcctcgata
    11101 tatcgacgtt ctttaaaccc gattgtccgc tccatccgtt aatccttcac atatatgttc
    11161 cgggtgcatt gaattaaatg attggttgcg gtcccggata ctgcctgtcc gcgaaaaaaa
    11221 gaagggattt ttgggggtcg gaacagcggg gtactggccg aattgggttt tcagggacca
    11281 gaaccgcaat tctccggatg ccgttgtttc gggaaagaag cccggcattg tgccgtacgg
    11341 ttcgggaaga ggctgcgagc ctcgtgcaaa tgactaggag tgtaaaaaaa agaggtggtg
    11401 tgtctatcca atgaggtaga ctgcactgac ttcggctgtg accttcactt ctcccggttc
    11461 aatgggtgtc ggcgcctgtt catatgcgtt gtctcctgct gcatacgagg caagactctt
    11521 gtagagtcgg ggagggtagg aacccgcgac agtgatctgc ttgactcctg taatcgtcac
    11581 tcctgccgca cctgcaacga tcgatgcgtc cgagtaggcc tttttcacgg cttttgcgag
    11641 cagttcctcc cgcagggact gttccagttc ctcgctgacc tggaattcga tagagtcaac
    11701 ctggttggct cctgccctga cagcggtatc gattacctct cctgtccgcg aaatatccct
    11761 gatggtgacc tcgaggcggt ttgtaacccg gtagtatttc accttctgcc cgaacgggac
    11821 ttttgaatcc tcgtaaacgg ggtaaatgga gtaaccggtt gttttgaggt cctttttccc
    11881 gataccgaga ctctcgactg atttggagac agagtccatg atgcgtgcat tctcgctttg
    11941 tgcggcctgg acgtttgcat tctcggtgac gacagagaca gtgatgtgcg ccctgtcagg
    12001 ggtgaccatt gtttctgcgc tccccgaggt ggaaatcgtc ctttcgttgt tctctgcagc
    12061 ggcgacagtc cccggtagga aagccgcgac gaggacgaag acgaggagaa gcgaaaagcc
    12121 cttcgtgatt gcctgtggat tcataccgtg taatatcctt ggaaaattca aatacctttc
    12181 ctaaactgcg aaaaaaatcg caatcattcg tgttttcaat accggttaat cccccgcatc
    12241 attttttggg ggaatttcca ttccatacca aaatacaaga agaaggacgg tgcatacatt
    12301 gatggttctt gtatggcatc aacgctggtc gagaagatat tctcaaggaa atgtgcacgg
    12361 gacgtcagag caggtgatgt tgtcatggca ccggtcgaca tggccatgat ccatgacatc
    12421 accgggcccc ttgctgtcca gaagttccag gagatggggg gaaaaaccgt ctttgatccc
    12481 ggaaaaatcg ttcttctctt cgaccaccag gtgcctgccg attccctatc agccgccagc
    12541 aaccatgtat tcctgaggaa atttgcccgc gagcagaaca tcgaaaatct cgacgggaga
    12601 gagggtatct gtcaccaggt ggtgatggaa cgcggtcgtg cggcgccggg cgagatcatc
    12661 gtcggggccg attcgcacac gtgcatgtac ggcgctgcgg gcgcgtttgc gaccgggata
    12721 gggtcaactg atatgggttt tgtcctcaag ttcggtgttc tctacttccg tgtccccgaa
    12781 acgatcaggg tcacggtcgg ggggaggttc cccgggcggg tggggccaaa ggatctcatc
    12841 ctcgaaatag ccgggaagat aggggccgac ggtgcgacgt accaggccat cgagttcacg
    12901 ggggagactt tcaggacaat ggacatgccc ggacggatga catgctgcaa catggcggtt
    12961 gagatggggg caaaagcagg catcgttcca cccgacgaaa taacgtggtc atacctcgca
    13021 tcaagaaggg atattgcgcc attttcactt gccagcgatg ataatgcgtc cttttcgatg
    13081 gaatattcat tcgatgcatc gcgtctgtcg ccccgggtgg cagtccccca caacgtggac
    13141 caggtcgtgg acgtcgcaaa ggtcgccggg acgcatatcg atcaggtctt catcggttcc
    13201 tgcacgaacg ggcggttcga agacctcaaa gaggctgccg atgtgctcaa ggacgggacc
    13261 ttccacccgg gtgtccgtgt catcatcatc ccttcctcgc ggacagagta cctcaaagcc
    13321 ctcaaagccg gcctgattga acggttcgtc tctgccgggg cactcgtcga ggcgccctgt
    13381 tgcgggccgt gcatgggtgg tgctttcggc ctgctcgctc ccggtgaagt ctccctctcg
    13441 acatcgaaca ggaacttccg gggacggcag ggaagcaccg atgcgttcgt ctacctctgt
    13501 tcacccgcga cagccgcagc cagtgcaatg aagggcgaga taacggaccc aagggaggtg
    13561 tgaaggatga gagtgtggaa gtttggtgac aatatcgata ccgatgccat cataccggga
    13621 cgatacctcg tcatctatga cccgtgggca cttgcaaccc atgccttcga aggtacccgc
    13681 gatgaatttg cccagaacgc acgggaaggg gatatcatcg tcgccgggaa gaactttggc
    13741 tgcggctcct cgcgggaaca tgcacccctt gcactcctcg gcgcagggat cagggtgatt
    13801 atcgcccggt cgttcgcccg gattttttac cgcaatgcaa tcaacgtcgg gattctcccc
    13861 ctcgtatgtc ccgaggccgg gtcaatcgag gacggggcgg tcgtgaccat caaccttgat
    13921 gcgggtttca tcgagtcggg gggaagaaag atgccaatcg aagccgttcc tcccttctta
    13981 aaggaaataa tcgatgcagg gggactcgtc gggtacgccc gcaagctcga gaaggtgaag
    14041 acatgtacag aatcgcagta atcggcggcg atgggatcgg ccccgagata gtggccgagg
    14101 gaaaaaaggt tctcgaggct gcagcagacc gtttttcctt cgacatccag tgggaagact
    14161 tcgacatagg ggcagaacgg tacctggaga caggagagct cctcacagag gaagacctaa
    14221 aagagctcgc cgggttcagg gccatttact tcggggcagt gggagacgag cgcgtgaaac
    14281 ccggtgtcct cgaaaagggg atcctgctct ctttacgctt cttcttcgac cagtatgtca
    14341 acctccgtcc cgtccgcctc ctcgagggcg ttaccacacc ccttgcaggc aaatccccga
    14401 gggacatcga ttttgttgtc gtcagggaga acacggaaga cttctacgtc ggcgtggggg
    14461 gaagggtccg cggcagggac agggcgacac atgagatcgt gcgcaccctc tacaacatca
    14521 ggtttggaat cgactgcgag agcgatgcag acgagatggc ataccagatc ggaatcatca
    14581 cccgcgaagg ggcaaagcgg gtgattacct acgcatgcaa tcttgccggg aagaggagga
    14641 aaaaactgac ctctgttgac aaggccaatg tcatgaccga catgtacgga ctctggaggg
    14701 aggtcttttc cgaggtctgc ggaagttaca aggatatcga gacggagttt gctttcgtcg
    14761 atgctgtcac catgtggttc gtgaaaaacc ccgaggcctt cgacgtggtg gtaaccccca
    14821 acatgttcgg ggacatcatc acggatctcg gggcaatgat ccaggggggc cttggtcttg
    14881 cagccggggg aaacatcaac ccgaaaggaa cgtccatgtt cgaacccatc catggatcgg
    14941 caccgaagta taagggtctg aaccaggcaa accccatggc cacgatctgg gcgggatcga
    15001 tgctgctcga ccatatcggc gagaccgagg cagccgaaaa ggtacttgca gcaataggcc
    15061 ggtccatcag ggacggaatc gtcacgaagg acatgggagg cacgtcccgg acatcggatg
    15121 tcggcgatta cattgctgcc ctcgtaaaaa agatgtgaag tcactttttg ggggatttca
    15181 tgccgtgcag ggggagagtg gccctgcaaa gtctgtcagg aggtggttgg ggggatacct
    15241 cttcccgctt cctgcatgga attccatgat gggggcagcc ctttccctgt aggagagcac
    15301 gtcctggagt gagtcaaggg aaagcgtgaa ccggtccccg ttcacgagca ggatgttgag
    15361 ggctttcccg gaccgggaga gcgatatgga tcccgcttcg ctgccgaggt actccatcca
    15421 gttctgcttg atacgcctca cggaaccggt cgttcccctc ccgatcacac cggtgagttc
    15481 ttcgacagga atgcagagcc gtgccccgtg aatgaagagg aaaacgacct cccggggaac
    15541 accctcgccg tcaaggacct cgtgcccgtc cctgcagagg tatcctgccc ttttcatggt
    15601 tctttctcac ctatacacca cctctggaag gactggtata taaaccctcg atgagcgcgg
    15661 ggtgaaagtg aaaccctgaa ggtcaggggg aaggatcgtc ccgtctcctc tttgcgtggt
    15721 ccatgcaggc gttcagcaca gattcaaaga gtgcgagtgc tccctcgata ccggcgaggg
    15781 gacgggaatg gagcctgacg gtccccctga ggggcggtgt caccccgaca aatgcggcac
    15841 cggggcatgc atacttctcg aacgatgatc cgagcacgag gtccgggttc tcacgcgaga
    15901 ggatttccac aacggtatcg taatctcgtg ccctctcgac cctgtatttc ccggggacgg
    15961 gggggttgcg tgatccgatc acgaggatat cggcatcgag gtattcctcg agcatcaggg
    16021 caatctcctg catcgtccgg cactgcccga agagcgcgac atgcggcggg tcaaactttt
    16081 ttatgaaacg gtcacaggcc gcggttattt tctcacgggc gagggggata tcgtgttcga
    16141 gcaggtcatc cgctccaccg gtaaacgatg cgatcctcct gatggcatcc tcgatccggg
    16201 aaagcccgac aagacatccc agagactctc cgagatcaag ggtcaggtca gggttggtat
    16261 ggagggtgta tggggagagg ggttgtccat aacggtactt ccctgatggg agagccgcac
    16321 ccgccaccgt cccggccagc ccaagcagcc tttgtgcctc ctggaagttt ccctgccgga
    16381 acgggtcaaa gggggagagc ccgtcgatgt tcacgccggt cttcccgccg gatacggggg
    16441 gatcgatcgc cctgatggca gaccggaaac cgtcctcgta ttctcccgag aaaccggctg
    16501 catcgataac acagatccgg gtgctgtctg aatacgcctg ttcgagcatc ccccggatat
    16561 cctctcccgt gatggcaggg atgcaggtgc agagcacggc aaccagatcg tacttatcac
    16621 ggattgcgtc gatggtgcgg acgagtgcgt cttctgtgcc gagtatgatg tcccggtccg
    16681 tgacagaaga acagtacagg ggcaggtgga ggaccgatga aggataatag tagcaccctg
    16741 ccgatccatg gatgacgacg cctatccccc cgattcctgc gagggccgct gctgcaccgg
    16801 tgagggcaca gggccagagc ggcccggaac aatcatgcac ggcaggcccg cctccaccgg
    16861 taaaggagcc tccgtatccc ctcggtgccg accgggaacg gttccgggac ggggacggga
    16921 tatccttccg ggtgaacact catgccggcg gcagacgcga cctccctgca gacttccgag
    16981 tcggtcctgt ttccaaacgg gtcacagaat ctgacccttt tccctctcag ggaacggaat
    17041 tcatggaata tgcgggcctg tcgcgcctct tcttccgcga ttgcacctga aacatcgagg
    17101 gaaaagacgc ggcccacctc ttcgaggaat tggatcgtcc cccgggaacc gatgggaaac
    17161 gagctgatga acggtgtccc gaacctctct tccaggaatc gccccacccc ctccatcgag
    17221 gggtcccgca ggatgttgca tcccccgcgg gagagccggg atatctcccc gacacttgtc
    17281 ctgcagacga accgcgtgca gatgggtatc ccgatcgccg caaggagcct cctgacctcg
    17341 ttgaaatgct cgtcccgttc ggtttcaagg gtcttttccc cgacgaggtt tgcggaaggg
    17401 atctttccat cgtcctccgc aagggaggag agtgacatca gggcctggac atgaccctgg
    17461 tggaaaccgc caccaagaaa ccccgcggtc ggtatggaga tcaccggtat cccgctgaaa
    17521 ccccggcaga ccgcctcgac atcgtccccg atcgcccctg tgacacatgt cgaaagaacg
    17581 cagatgatgg agggattttt tccggaagcc ctccggatcg ccgcatcgag ggcatcctcg
    17641 ccaccaaaga tgatgtctgt ttcggcaaga tccgtcgaga gaacccgcgg gagtcgcggg
    17701 tcgtccctgc cggcgcagag cgcatggagg agggaaaaat tgtgatgggc acaaccggag
    17761 ggtccgtgga tgatggtcag ggacccctcg atctcggttg tcacggagag ggcacctgtc
    17821 agggtgcacc cgctgtcacg gggagtactc atatgcaagg ttttcaaggt cctctatccc
    17881 gagcggaacg ggaatatcca ttctccggtt atccatcact ctcgatgcaa gttcccggta
    17941 gacggctgcc tggttgctcg atggagcgta ttcgaccacg gttttcttgt tcagctcggc
    18001 ctgctggacg acctggtccc gcgggatgta caggacgagg aaactcccga tacgttttgc
    18061 aaattctgca acgagttcct cctcgcgggg aaggttcttt gcgttgcaga tgactcccgc
    18121 aagcctgcac gtgctcctcg accgggaaga gagacgtgat attgccttgc agatgttgtt
    18181 tgccgcatac agcgacatca gctccccgga cgtgacgagg tatacttcct ctgcataccc
    18241 ctcccgcatc ggcatcgcga atccgccgca gaccacgtcg cccaggacat cgtagacgac
    18301 gacatcggca tggagggcac ccagtcgttc gaggatctgg aaggttgcga tgatgccccg
    18361 tcccgcacat ccgacacccg gttccggacc acctgcctcg acgcaccgga cacccatgaa
    18421 tccttcgtag acaatgtcct cccgggtaat atccgtgtca cccctctcgc ggaccaggtc
    18481 catcacggtt ggaatcagcc tcccctgcat cagcatccgt gtgctgtccc tcttgggatc
    18541 gcacccgatc tgcatcacat cgagcccgcg gcaggcaaga gcagctgaaa ggttagccgc
    18601 ggttgtcgat tttcctatac ccccctttcc atagagggcg atctgtttca ttgggtacct
    18661 ataggttggc gttcataatt agatattttg taattaacca aaacaaaatt gaataagtct
    18721 cccgggacct cagtcgcttc ccttcaggag gcccgtgaag agaacgatga caggaatgac
    18781 atcgagccgg ccgatccaca tcacgaagat gaagacccac ttggagacca gtggcatcgt
    18841 cgggcccacg tatccggcac tgacaccaca cgagctgaga gccgagacga tgtcaaagac
    18901 aagaaccgtg acatcgcagg agatgatgtg tacctgcagt atgaccattg tcgcgatgaa
    18961 gaccgtgatg acagaaagaa tgatgacaag catgctcttg gagagctcag gttcggcgac
    19021 ctcgataggg acattccttc cctggtaccg gaacggcacg agcaccgtgc tcctgacgaa
    19081 tgcacgccgg aaccaccaga caatgcccct gtacccgagc gcgatccggg agaggtgcag
    19141 gccacctgct gtgctgccgc ttgaaccgcc cacgaacatg aacattgtca ggaagacgag
    19201 agtgacgctt ggaaaaaggt aaagattggc gttctggaac cctgtcgtgc tcatgacggc
    19261 agtcatcatg aagagtccct gcctgacggc ctctgcaggc gcataccggg caatgaagag
    19321 gaggtcggcg atcacgacga gagaaccgaa acaaaggaag tatatgagga ttctgacctg
    19381 ttcgtcagag aaaaacgata ttttccggtt ttggtacgtc atgtaaaaga gagagaacgg
    19441 aatcgatccc atcaccatga ccgggataag gaggaactcg agggtcgtgt tgttgtatga
    19501 ggagacacct ccggcgacag gaatgaaccc ccctgtcgag attccggaga gggcgaggtt
    19561 gagggcatcc cagagcggta cccttgcaac aatgatgatc ccgaccgaga tcaccgtgag
    19621 gaggatatag actgcccaga tctcctttcc attcgcgacg atgcccggga tgatcctttc
    19681 agacctgctc tccgggcgga aaggagccat ggtatcgagg tttgaccgga acgcgatggt
    19741 aagggagagg gagatgattg caagccctcc cagccactgg atgtacgtcc tccagaacag
    19801 gaggctccgg gggagaaggt cgatatcctg gaggagagaa aaacccgttc ctgtccaccc
    19861 ggccatcgcc tcgaagagtg catcggtgaa gggaatgtca agcacaatca tgaagggaat
    19921 gcacgaaaca acggcaaaag agagccagag cagggcaacg gaacagagtg ccgttgaaaa
    19981 cccgacatcc cccgggtgcc ggggaatgct gttgagaatc atcccgccgc cgaagaagag
    20041 gaggggcacg attgccaggg gcaggaggag gtcccattcc cggaaaacga tggcaacaag
    20101 gagggcaaaa agcgtcaggg gactgatgaa agtgagcatt tcgccaagct ccccaagaac
    20161 gatcgagaaa tacctaatcc tgcccattac tccctgatct gttggatagt cccggatgat
    20221 gtaagtttgc ccatggatat cccgggctcc gtgacccgcc ctttaagacc ctgttccgtt
    20281 atctgcgatg gagagcctgt gggtgacgat gcacccgcac acaaagagcc tggtaaaatc
    20341 ggtcggcgtg agcatgcggc actcctgcag gaggttcccg ggatcccggc ccgtcgtctc
    20401 ctcaaggaac gcaacgaggc tttcggaaca ggtgcagggg agcatcccgt ccagttcgat
    20461 ggtgcctgcg ggcctctttt gataccctgc cggcctgaag agaaacgaga aaggtctccc
    20521 gtgagccgag gttatgcccc ggaagtcaaa agagagggat gcgctggcag ggtagaaatc
    20581 ccagggggag agatcgaggg tgacacggta gatgttttcc tcccacccga ggttcctccc
    20641 gaaacgcgag aaggaaatac cgataacgac ggttgcatgc tcgcgctgtg gtgccacata
    20701 ggcaaaataa tccattgccc tccgggtgag ctcgtccccg acctcccttt ccgtgtaacc
    20761 gcgggcgccc gtatcacgct tgaatttcca ttccttcttg acgtcgggat cgggatccac
    20821 gaaaagcgtg aaatcacaca ggcgtcgcag tttttccgta aaaaaagcat gcaggccctc
    20881 gaggatgaga atctttgccg gctggaaggg aaagggacca tgtatggtcc cgttggagtg
    20941 atcatagacc attttctgga tggacaaccc ctgccttagg cggccgacat ccctttccag
    21001 tcgatcaaaa tcgtttgcat cgggggaaag cggcgttatt ccccgttttt tcctctcttc
    21061 ccggtcgtag agatggtaat cgtcgagtga cagggtcgcg acaaggtcgt cgccgaggag
    21121 gtgccggatt gccgatgcaa aggtcgtctt gcccgaacca ctgtcgccgg ccaccccgat
    21181 gacgtagaca gagccggacg cattcagggc tgaaaggagg ggaggtaccc tgcccacgac
    21241 cttacccgcc cccgtgccaa aacaccggcc ggcccttttg ggaacaaacc attcttccgg
    21301 ctctcctgct ctcccttcgg tcgggaattc actggtgtat cccgatctcc ctgtgcttcc
    21361 cgacgatggt atcggcaagt tcctcgattt tcttctggtc ggaagcaccc ggtgctcccc
    21421 tgatatagac aggttcgagc aattcgggct tggtccgggt gagcattccc ttgagcgcct
    21481 cgatggtatt gccaccccac ccgtacgaac cgatgacgga gaggaaccgg gtctttggtt
    21541 tgagcatgtt gaagaggtat gctgcataga ctgcctgcgg gtggggaccg aagaggacag
    21601 tcggtgtgcc gatgacgacg gtcgccgcat ccacgagtgc cattgcaagt tccccgatgt
    21661 ctgttaccgt caggttgaag ggttttaccc ggatgccgcg ctcgatgaga gcctcgcaga
    21721 ggtggttgac catcttctcc gtgcttccgt gcatgctcac gtaaggaatg acgacttcgt
    21781 ccttcacagt gtctgatatc cagtccctgt acgcgtcgag gatgaagccg gggcgggaat
    21841 gaacaggccc gtgactgggt gcaatgatgg aaacagggat gtctttgagc ttttccatgt
    21901 gatccgcaat gttcctgcga aacggcatca tgatctcggc gtagtacctc tttgcagaga
    21961 tgtagacctc gcgttcatcg gtcacgaaga gggaactctc cgcgtaatgc gtgccaaaga
    22021 ggtcgcagga gaagagcacc ctgtcctcga cggcataggt caccattgtc tcgggccagt
    22081 gcacccaggg ggtaatgaag aactggaggg tctttcctcc caggtcgagc gtatctttat
    22141 cctttatttc catgcaccgg gccggatcca catcgaggac ccgtgtcacg aggtcctttg
    22201 atttctcgtt gacgacgatt gaggccttcg ggaagagctc ggcgatcatc gggagcgaac
    22261 cggagtggtc ctgctcgaca tggttgatca cgatgtagtc gatggtatcg acccgggctt
    22321 tcaccaggtt ggtaacgaga tcaagttcct ttgacggatc cacggtatcg atgagggcag
    22381 tcttcttcgc ccccttcacg agataggagt tgtacgtcgt cccatgcggg aggggtataa
    22441 gggaatcgaa gagcctgcgg tcgaaatcag gggcaccgac ggcataaatg ccggggacaa
    22501 tctcgcggac tgacatcggg atctcccctc acagtctcct gaacagggcg ggtgctgcct
    22561 tgcagacagg gcacttccag tcacctggca attgggaaaa atcgataccg ggcgggatac
    22621 ccatgtcagg ctctcccttc tccgggctgt aaacatgccc gcatatggtg cacatgtaag
    22681 aatccatttt ttcttctcct tttcctgcca actctggctt tttctggcag tagatgtaga
    22741 ggacaggcag gcataagtgt tttctttatg gaacgggaca gtccggagtg tatcacaaca
    22801 cttttctttt ccgacgctct gaagtgatga aaaggacgaa ccagcctatg acgataatga
    22861 aaatccgtgg tggcgacctc gatctcgtcg aatatgaatt tgtcacgttc agaccggggg
    22921 aacaggtaaa gactgccggg atcgtctgtt cccggcccgt cgtcccgttc tccggaacgg
    22981 ttaccgtccg ggcacctgcc cgtatccacc tgaccgtgct cgatatgaac cggttctcgc
    23041 cgtcccggcc gggcggagga ggtgtcgggt ttgcaatcca gctctactgt accgtttcgg
    23101 tctcctgcac ggagaaggag atcacgatcg attacaaccg gcctgcgatc atccggcact
    23161 tcatcgaggt gttcaggaaa atttcaaggt ataccggcgg gtttgcagtc tccgcgcagg
    23221 atcaccagca ccagcacgtg gggctcggtt cgacgagtac catcatgatt gccctcgctc
    23281 acgctctcaa cacggccgtg ggttccccct tctcaaatga ccagctccgg aagatgattg
    23341 ggtataacta cgtcgaggag acggtcgaag gcaacgttgc attcggattc gagacgggag
    23401 tcggcccggc agcttccacg tatggcggga tggcaatcat gggggatgac ttaaccctca
    23461 tctaccacca cccgtttgcg atgggaaagg acgtctatgt cgtcatcccg ccaagcgaca
    23521 tctcgtcggc cgggacaaag gagtttgacc tcctcatgaa caaggcgagg gtccttgact
    23581 accgtgacag ggaactcaag gcttacctca tcatgatgga tttgatcccg gccctcgaga
    23641 agggggatct ctccaaaatg ggggatatca tctgggaatt cgacttcagg gggtcgaaga
    23701 gggcagaggt ggaacaccat agttttgcca tctaccatta catgagcagg ctgcgggagg
    23761 cggggctcga gttcgtgggc atgagttccg tcggcccttc catctccatc attacgggca
    23821 gaccacggtc cgaagtcgaa aagatcgtcc gggacctcgg gctctcggtt gcggtcacga
    23881 ctgcagttga caacgagggc ttaaaggtct ctgtcagcgg gaaataggca tcgaccgttt
    23941 ttaccgcagt caatccccct catttttacc gggttcccgg catgcgtccc gggaataaaa
    24001 gggacatacc catgaagaat gctttatccc ggttatggca aaatgaatat ggttacacct
    24061 ttccggaacc tccggcgccc cgggttattt ccctggaacc gggttccacg aaaggacagg
    24121 aaagcgtcac gcatgcatga gtttggaatt gcctacgaca tctatgccac agcacggaag
    24181 gcggccctcg agaggaacgc acgggatgtg agggaggttc acgtggaatt cggggagatg
    24241 gccatggtta accccgagca aatagccttc ctgtacgata ccctcatcga ggatgacgcc
    24301 ctcatgcggg gttcccgcct gacatggtcg gttgtcccgc ccctgacgcg gtgcacatgc
    24361 gggtacgagg ggtccgagcg attcgtgtgc ccgcggtgcg ggaaatttcc ggaactcgtc
    24421 agggggctgg aagtcatggt gacgcacatg gaaattgagg tggacgacga atgaaggtca
    24481 cactcatgca tggtgcgggg ggagaggtca tgggggaggt cctccagatc ctgacccgga
    24541 tggagcaccg caatgcaggc ggcatcggtc ttgaatccct cgacgatggt gcggttatcc
    24601 ccctcggcgg gcagaacatt gtttttacga ccgattccca cgtggtccgg ccggtattct
    24661 tcccgggcgg ggatatcggg aggctcgcgg tctgcgggac tgtcaacgac cttgccatga
    24721 tgggtggaag gcccgtcgcc ctttcctgca gcatggtcat cgaggaaggc tttgattcca
    24781 aggacctgga gaggattgtt gcatcgatgg acgcggcact cggggaatgc ggtgcgagta
    24841 tcgtgaccgg ggataccaag gtgctcgaga aaggggcact ggacgggatc gtggtgaaca
    24901 ctgccgggat agggattgca gagaaagtca tccgcgactg cacgctccag cccggtgatg
    24961 ccatcatcgt gaacggcact ctcggtgacc atgggctgac catcatggcc gagcgtgccg
    25021 ggctctcgct gggctcgcag ctgaagtccg atgtcgcacc gctctggaac ctcgttgccg
    25081 gggcactcgc agcaggggac atccacgcga tgaaggaccc gacccgcggc ggatttgcaa
    25141 gtgccatcaa cgagatggca aggaagagca gggtgggcgt gaggatcagg gaagaactga
    25201 tccccctcaa aaagagcgtc aggagtgcat cggagatgct cgggatcgat cccctccagg
    25261 ttgcaaacga gggcaaggtc gtgatgggtg ttgccgggaa ggatgcggaa gcggtccttg
    25321 cagcactgcg ctcccatccc tacgggaagg acgcagcaat catcgggacc gtcgtggccg
    25381 gatccggggt tatcctcgag accgagatcg gcggggaacg gttcatcgag cccccgatcg
    25441 gcgatcccgt cccgagggtc tgctagacca tccggaaacc ggatttacgg gaaagaaaat
    25501 cctcgaggag tgccagagcc tccttctcac gggggccacc gcatctgcgg acaatcgagg
    25561 catggtgcga aatgagctgt tccagctggg agtcctcccg ccggacatac cgcgtcgcat
    25621 gaatcgtggc ctctatcacg ctcgaaaagc ccctgttgac cgggtggata gtacaggaaa
    25681 ggacctcctc gtggagaggg gtcaggttta cgaccagggc ttcgcccgta tctcttgtca
    25741 cttcggcacg gaatgcaacc caggcctctg ccgaagaaag cctctgcacc acaaggtcac
    25801 cgattgtctc gcgggaaaaa aaacggggtt cgagatcgga gaacgcagtt ttgacgtaaa
    25861 ggaccgggtc gtggatgatg tttgcaacga cccagccata ccgggagata ttttcggacg
    25921 tgtgactgcc gtggaagacg accatcgtat ggctgccatt gcgaaggatg actcccatgg
    25981 gtgctgcatt gtccttcgtt gtcgcgatga cctcgttgat accttccctc aacagtccca
    26041 ttcccacccc tctccaaggg cagtgtagat cgatgcaacg ataatatctg cgatagagcc
    26101 ggggttgatc cccttctgga tgcactcctg gtcaaattcc tggaggtcgc gcacgccttc
    26161 caggacttcc cgtgccctcc tcatggtcat cccggcaact tccggaccat gtttcttgac
    26221 aatgaacgta tcgggttcga gtgcaagcag cgagaggaaa gcttgcacta ttccctccct
    26281 gccgcatcct gccgcgtgca ggaggtctgc tcccctccgt gtcatctgga acacggagac
    26341 ccactcccgg gcgaccatgt cccttggggc agaatagagc atgaggtcat aaagcgtcat
    26401 acccctgtcc ctgatctcct gcagggagga cgggtcattg acatcgagtt cgtgcccggg
    26461 aatgaccctg acacttgtct ttccgaatgc acggtaaaat tcgattgaat cttcgacggt
    26521 ggtttcccca atgagccgca tcgcaccctc gatgccatca cctgcaacga ggggcataag
    26581 aaggatgaaa gcgccgaaat gcgtgttacc acccgagtat ccgcccgtga gtgcaacagc
    26641 ctcgtgtatg agacttccca gtcccctgcc gcccctctcc gcggcttcca gtgccgggcc
    26701 tgccatgatg gcagaggcga gaaaatgttc gaggcgcgtg gtgggaaagt cgtggcaacg
    26761 gtccacgttg cctggtttgg gaaaggccga tacctcaaga accatcgcga gctgggcgcg
    26821 ttgtgcacgt gtgaggttct gcatctcttg aaaaaagatg ttgtatgatc ttatcagcca
    26881 attgtttctt ctgcctcatg tactcctggc gggagaggcc tgactgggcc agcgtcatgt
    26941 cccggaacat gcacggcgag gataccttgc agcaccatgc caggctcccg aaacacgtct
    27001 gggcaccggg ctcaaggggc gttcctgcaa cagccttctg cttgaagctc aggtactctt
    27061 cccgggaaag acccagcctg tcaagcatgg gcaggagggg acagttcttg acaggcatac
    27121 agcagaacgt gagtgccctg atatccccgc cgcgacagag ctgcttggga gcattgtacc
    27181 acccctgttc atccgtgaga cgttcgatgg ctgcatcaag cccggcgagc gtgcggacat
    27241 ctgcgttccg tgcaagggag acgaggtcgg ccccgtgcga gaacatgtcc ctgaccctgt
    27301 cgaaggtgtt catggaattg ttcgcgatga ggaccagcgg gcacgagttc ctcatctgcc
    27361 gcactttctg gtagtcatag tccatcaggt cgacatggat gatgtcggcg ccggccttcc
    27421 atattttccg tgcgaggagg cggtcatcgg gactcacgcc tgcccggatc tttaccgaga
    27481 cagagacatc ctcgcgtttc aaagccctga tctcttctgc gaggagatcg gtatgggaaa
    27541 ggaggtattc accggaacgc gcttctacca tcggttcctg cctgcagtgg gcatcgatct
    27601 cgtagatggc ctggtcaccg aggtgggacg caattgctgc aaacgattcg ggtgaactgc
    27661 cccggaggtt caacccgacc acgagacccg acccttcgag ccgctgtacc tgccctgcca
    27721 gctcttccac cgggtccccg aacaggaatt ccctgcgacc ggaacgttcc atggccctgc
    27781 tggcctccat cgtgggagca tcgatcgaga aaccaccaag gaatgcaaca ccgacatggg
    27841 atgcgcgggc aagggcatag tccgcgtcca cgatgcctgc cattgcagag agagccaggg
    27901 gggtcctgac aacctgcccg ttcaggagga gattataccg ttcaaaactg cgcatcattt
    27961 ccatcggtgg accatccgtc cctcatcgga ttcgcggtat ccgaagttct tataaatacg
    28021 atgtttctgg atataaaggt aaactatccg ctcttaaaaa gcgtctccta tcccctgttt
    28081 ccatcccgtt ttctccaata aacgactgcc ggggggaagt gacgcagaca gaggggacat
    28141 tgtggaaatg ccgcgagtat tacatttaaa cgtctttcat cttaaatcgg caaccatttt
    28201 acccatggta gtaataccgt atggtatatg ggtaaaaaag gactgttact ggtcggacac
    28261 gggagcaaac tgccttacaa taaggaactg gtcgaaagta ccgcacggct catcgggaaa
    28321 aggtgcccgg aatacgttat ccggtgcggg ttcatgaata tcaactcgcc gaccatcagg
    28381 gaagccctcg agcagttccg gaaagatgca atcgatgtca ttatcgtggt gcccgtcttc
    28441 cttgccaagg gagtccatat cctcgaggac atccccggcg agataggcct cgcaaaagga
    28501 caggtgaagg gggaattcgc cctcaacgga aagaccattc cccttctcta tgcagacccc
    28561 atcgggagcg accctctcct cgctgacctg atgatcaaga acgcggaacg tgcattaaga
    28621 gaactctaga taccccccat gcgcatcctc gtcctcgata ccatccatgg cggccggacc
    28681 attgcccttg ccctcaggga aaggggccat accgttgaca tggtcgatat ctacagggga
    28741 aaggaaggaa tcagcccgtc tgatgcacgt tccggtgatt acgagatgat catcgcacct
    28801 gtccacctcg atcccgggca cccgctcctc cgcgacctgc ccgcccccct cgtttcgcac
    28861 cacgaggcgg tcaggtggat catcgggaaa caggcccctg cacggttcat agaggtgaca
    28921 ggtgcgaggg gaaagaccac ggtggccagt gcaatggccc acgtcatgca gggtcccggc
    28981 attcttcata cgtcccgggc gacggttcgc ctgccggaga atgagacgat ggggagattg
    29041 gggatcacac ctgcctcgct cattgctccg gcacactctg cgtattccca ggaccgatgg
    29101 ctcatcgggg aggtatcgct cgggttcgtg ggtgcgggca acctgggtat cctctcctct
    29161 gccggaacct atacatttgg cgcgggaaag agggatgcgc tctctgaaaa actccggtca
    29221 ggaaacaggc tccccctcat cattgtgccg ccggggttca gccggtccgg aaaccggctc
    29281 cctgccgatg aagtcgctct ttctgaagga agcatgtgcc ggtacgaatg ggacgggatt
    29341 acgggcaggt acgaaaaccc cctcctcgtg acgaaggcct accgcgaccc cctgctcctt
    29401 gcgactgcag cagcctgtgt ccttggtatc gacccttccc cccttgccgg ttttaaaccg
    29461 ctggagggaa gaaaaaccgt ttcatgggtt ggaagaacac tcgtcatgga cgattccaac
    29521 tcgggaacct gtgcaggaac agcccgtgat gccatccgcc tcgcccgtgc acgggcaggg
    29581 agaccttccc ccctcgttct cgttatcgga aaggaagcag gggcgatctg cgaaggtttc
    29641 ccgccggacg aggttgcatc ggtcatcagc acggaatccc ccgatcacgt catcctcgtc
    29701 ggggattatg acctggatga ggtctgccgg cgctggaaag gaaaaggctc cgtcctccag
    29761 gcacgcaccc tcgaagaggg gagaacccgt gcgatgcagt ttcctgatgg gagcattgtt
    29821 gtccttgcgg tgaaaacatg gcgttgaaga cgatgaaata catgcagccc cggccaagtt
    29881 cgatcgttgc tgccctttac acggcaaggg atctcggggt cgatgtatcg gtcctccacg
    29941 gcccgtcggg atgttccttc aagcatgcga ggctgctcga ggaagacggg atgagggtac
    30001 tgacaacttc ccttgccgac cacgagttca ttttcggtgg ccagcagccc ctggaagcag
    30061 tgctccaata cgcggagcgg actttttctc cccggaggat ggccgtcatc gggacgtgcg
    30121 tctccatgat catcggtgag gatctccagg cggctatccg gaactcgggg attgtgactc
    30181 cgaccatagc gatcgagatc catgccggtt accccgagaa catcgcgggc gtcatagcaa
    30241 ccctcgaacc tgcggcagca cagggatgga tctcacagga ggaactggag aggcagaagt
    30301 tcctcctcgg gaaggcaaac gaggtggaac gcctccgggg cgcagcatca aggccataca
    30361 tcgagccttc ccgcggtgac ctcaagcacg tggcagcaga acggctcctg tccctcgtcg
    30421 actcggggaa gaggggtgtt gccatcatga acgcaaagaa ggagacggca tacatgtttg
    30481 ccgacgaact cctcgctctc cacgatgccc ggcccgctgc ggatatcacg tttgttgcaa
    30541 acctcgaaga gcgggggctg cccaaggtga gggaggacgc ccgccggatc cggacggaga
    30601 ttgaggggag gggactggat atgcagctgt gcggagccct cgacgagtac ggtgcgaacg
    30661 gagaggcact gggggaggtc atccgctcca tctcgcccga attcgcattc atcgtcggag
    30721 tcccccatgc aataccccct tccgcactcc agggtatcga gtgcatctcc gtcacgaacg
    30781 gtccccgcca ggtggaacca ctccgggagc agggccaccg catcgtcgtg gtcgaagtag
    30841 atctccaccc gcggacgctc ggggtgaaga atatcgtgga gagtgaactc ggggcggtca
    30901 tcaggagcat ggcatgaagg cgctgatgat agcgggcgac cgctccggga gtggcaagac
    30961 gagcatcacc cttgccatcg cgtccgtcct ctcccgtacg atggctgtcc agactttcaa
    31021 ggtcgggatg gattacatcg acccgtcgta cctctcggca gtaacggggc gaccctgccg
    31081 caacctcgat acatacgtga tgagcccgga ccaggttctc tccgtgtttg ccaacgggtg
    31141 ccgtggcgca gacgttgccc tcatcgaggg tgtcaggggg ctgtacgagg gggctgaagc
    31201 gctcgatgac tccgggagca gtgcatctgt cgcacggatc ctcgaggttc ctgttgtcct
    31261 cgtggtgaac gcacggagta tcacccggag cgccgctgca atcgtccggg gtttccagtc
    31321 gtttgacccg tccatcagga ttgccggtgt tatcctcaac aacgttgccg gggagaaaca
    31381 cgcggagaag gccggaaaag ccgtggaaca ttactgtggc gtgcctgtcc tcggcacggt
    31441 tccccgggac ccggaacttg aactcgggat gcgtcacctg gggctcgtcc cgttcaggga
    31501 aggccaggag gtcagcgggt tccgggagaa gatcgggacc atcacggagg tagtcaggca
    31561 gtcggtcgac accggcagtc tcctgaagat cgcacgcgag gtttgcctgc cggaagggga
    31621 ggccccatgg ttctcccgca cgaaaaaaga gcataccagg atcggtatcg catacgacca
    31681 cgttttcaat ttttactatg cagatctctt cgatatcctg aaagctcagg ggagcaccat
    31741 cgtgttcttt tccccggcgt ccggggatct tcccgacgcc gacgggtaca tcatcggcgg
    31801 gggatacccc gagatgcacg cggcggccct tgcggagaac cagaacatgc tcgaggagat
    31861 cagggaacgg tcacgggagg gaacccccct gtacgcggag tgcggcgggc tcatgtacct
    31921 gacccgggaa ctcgttttaa aggagggatg gcaggggaaa aagtcagagg agaggtactc
    31981 catgtccggc gtttttccgg gaaagacagt catgcctgcc cggcgtgtcg ttgcctatgt
    32041 atccggggag agcagcccgg aatctcccat gggagcatcc cgtttcaggg ggcacgagtt
    32101 ccactactcc gcggtactgc tgccacacga tacccgtttc gtatacaggc tctcgagggg
    32161 gcagggaata cgcgatggac aggatggtgc actcgtccgg aagaccctcg ggagcttttc
    32221 gcatctccac ccggtcggga gccatgccat gttttcgagg ttcctcgaaa cctgccgtga
    32281 ttcccgcgag gcgtgaacca atcagcaggt aaaaaatact atgagagaac actctatgct
    32341 tgcatgttcg tttacataga cggcacaatg taccccaaag aggaggcaaa aatctctgtc
    32401 ttcgaccatg gtctcctcta tggcgacggg gttttcgaag ggatccgcat gtataacggg
    32461 cgcattttcc ggctccctga acatatcgac cggctctacg attcggccaa agcaatcgat
    32521 ctctgcatcc cgctgacgaa ggatcagatg actgcggcaa tcatcgagac cgtccggaag
    32581 aacgggttta agaatgcata catccgcccg atcgtgaccc ggggggtggg agacctcggg
    32641 ctctgcccga caaagtgtcc gaagccgact gtcatcatca ttgcaacgga atggggggcg
    32701 atgtacggcg acctgtacga gaagggcctc cgggctgtca ccgtgtccat ccggcgaaac
    32761 ccctgctgca ctctcccgcc caacatcaag tccctcaact acctcaacaa catcctggca
    32821 aagatagagg caaactgcaa gggaggagac gaggcgatca tattcgacat gcaggggcac
    32881 atctccgagg ggtcagggga caatatcttc atcatcaaga acggtgtcat ctacacgccg
    32941 ccgacactga acaacctgag gggaataacc cgcatggtcg tgctcgagaa tgcaaaggcg
    33001 cttggaatac ccgtggtgga gacgaatctc gggtacttcg acctctacac tgcagacgag
    33061 gtcttcgtaa ccggtaccgc agcagaagtc gcacctatcg ttcacatcga cggccgcgac
    33121 atcgggtcag gacgccccgg gccgattacc cgccagctga tggcggcatt cagggctgcc
    33181 accgaaaggg aaggaacccc tgtctcctga atcagccgtc tgcacgaggg gatccctctc
    33241 caaaaccctt tttatcctgt aaacgaatat ataagggtca cctgctgcta tagtgtagtc
    33301 cggccaatca tgccggcctt tcacgccggc gactggggtt cgaatcccca tagcagcatc
    33361 ccgctgtttc ctctcttttt caaaaattac cttaaaaaag ggaagttttc tctcgatgtt
    33421 catttcctgt caaaaaccag gagagcaccc cctttctcga aaaaagaaat tat
//
LOCUS       DAOOJU010000019        32986 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1452_length_32986_cov_15.848380, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000019 DAOOJU010000000
VERSION     DAOOJU010000019.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 32986)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 32986)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32986
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1452_length_32986_cov_15.848380"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..155
                     /locus_tag="PK679_06035"
     rRNA            <1..155
                     /locus_tag="PK679_06035"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02540"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02540"
     gene            245..316
                     /locus_tag="PK679_06040"
     tRNA            245..316
                     /locus_tag="PK679_06040"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:277..279,aa:Cys,seq:gca)
     gene            323..444
                     /gene="rrf"
                     /locus_tag="PK679_06045"
     rRNA            323..444
                     /gene="rrf"
                     /locus_tag="PK679_06045"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            513..719
                     /locus_tag="PK679_06050"
     CDS             513..719
                     /locus_tag="PK679_06050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55552.1"
                     /translation="MDTGRLGGIRDRIISSGNMKENLKNEKTKENLILSHIIIKPDYR
                     EWIFTVVRDEEQYHSMTTPINLQG"
     gene            831..1259
                     /locus_tag="PK679_06055"
     CDS             831..1259
                     /locus_tag="PK679_06055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55553.1"
                     /translation="MLPRVILHSATSLDGRITDFPANPDLYYALAATWNPDVVLFGSE
                     TILAALRDNPSLAVPSEHEEIFRPPEGTNDTRPLMVIADSRGRVRCWDAIRRWPYMRD
                     LLAFCSSATPKDYFSYLEEQKIPAIVAGKDRIDMRGALGM"
     gene            complement(2351..3037)
                     /locus_tag="PK679_06060"
     CDS             complement(2351..3037)
                     /locus_tag="PK679_06060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HPC55554.1"
                     /translation="MDFHKDIPAAFPGLCVVEGTIRSIDNTGEIPRFDALREEIVIRI
                     RSRYTLEQVKDDPLFRAYRDFFWRVGVDPTKTRPASEALVRRILSGKDLPLINPVVNM
                     YNLASAETGIPIAAFDADRLEGDLTMRFAREGEEFLGIGMPKPILLRQNQVVIDDGRS
                     VIAVYPYRDSDATKVTRETKNIHLVTCGVPGVSPEKVIGAYRLCSGYLERFTGGTAEC
                     TGVFPPQDSY"
     gene            3285..3467
                     /locus_tag="PK679_06065"
     CDS             3285..3467
                     /locus_tag="PK679_06065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHS domain-containing protein"
                     /protein_id="HPC55555.1"
                     /translation="MPTDPVCYMVVDEDEATIRSSYRGQEFFFCSEFCKKKFEEDPAR
                     YARLARSLDIGPDISC"
     gene            complement(3492..4286)
                     /locus_tag="PK679_06070"
     CDS             complement(3492..4286)
                     /locus_tag="PK679_06070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC55556.1"
                     /translation="MERYEWNPADYAAHSRAQYWWAEEMIGKLDLNGTESILDIGCGD
                     GKVTALLASRVPQGSVTAIDNSASMIRLAREKYPRSLTPNITFLEMDALDIPFINQFD
                     LVFSNAALHWVPDHARMLRGVFRCLKRKGRVFFQMGGHGNASDILNLADAMIHSDPWK
                     DYFMDFSNPYRFFTAGEYRVLLGDAGLIPIRAELIPKDMVQAGKEGLSGWIRTTWLPY
                     TGRVPVSGRNRFISDLAESYLERYPPDSKGLVHVRMVRLEVEAHKP"
     gene            4446..5777
                     /locus_tag="PK679_06075"
     CDS             4446..5777
                     /locus_tag="PK679_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serpin family protein"
                     /protein_id="HPC55557.1"
                     /translation="MNSTPAAIAALASFCMLALVLAGCTGTGIPGPSPHGQTTAPSVS
                     ETPTPSTTFPASHGFEKDVVEANNRFALDLYTRLADDPANRNDNLFFSPFSISSALAM
                     TCEGARGTTAGEIRSVFHFPENQSTMRSGFAEIIAGINNKTNAYTLRTANALWAEKTY
                     AFLPDYINTAERYYGARVTNLDFVNAPEEARITINRWVEGQTENRIRDLIPRGVIDSQ
                     TCLVITNAIYFKGTWKKQFEKEKTTDAVFRTANGSAVQVPMMQRTDENATFGYMETET
                     YQALSLPYESGGSRDISMLLILPKGDSLAEIERSLGPDMYDDICHRLVEKRVKVFIPR
                     FSLKTRYFLPRVLSSMGMPLAFTAGADFSGMDGRGGLFITNIIHQAFVEVNEEGTEAA
                     AATAVILGKGISPPEEKIPVFRADHPFIFFIRDNESGNILFMGRVENPVSP"
     gene            5967..7472
                     /locus_tag="PK679_06080"
     CDS             5967..7472
                     /locus_tag="PK679_06080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - ribonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="HPC55558.1"
                     /translation="MPRERSLLNCMKKHRIDLKAIARKVMEKYGFVSDFPPAVIRETS
                     SIEEVQSIEPDKDTRDLRSLLWSSIDNSDSEDLDQVEYCESRSDGEIRVFVAIADVDF
                     FVRKGSNTDRHAAFNGTSVYLGVETFPMLPDHLSKGVSSLLPGKDRRAVVIEYTVLPD
                     GTVKHGAIFRAIVKNHARLVYEEVGDWLEGKAPIPSGVSGVPGLEEQIRLQAEVARRL
                     RAHRMKQGALDLETIEAQPVMEGGAVRGLVIQEQNAARQIIEEFMVAANGTMVHVLGA
                     AGVPMVQRVVRVPKNWDGIVRTAAQYGFHLAGEPDSKALARFLDTRRRADPERFPDLS
                     LTIVKLMGPGEYVPFVPGDTPIGHFALAVLDYTHSTAPNRRYVDIINQRLLKAVLDGK
                     PMPYSAHELAGLAEHLTDRDKAAEKAARFMRKVAAAVILRDRIGQTFDAIVTGAADKG
                     TYVRLFDPPAEGRVVQGERGLFVGNKVKVRLIDTDPELGYVDFACVGRDKR"
     gene            7514..8341
                     /locus_tag="PK679_06085"
     CDS             7514..8341
                     /locus_tag="PK679_06085"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HPC55559.1"
                     /translation="MPAPVILVTGSTDGIGKAMVRKLADSDAEIIIHGKDSVKGRETI
                     REIKGLSWNRNIDLIIADFSIQEEVRRMAEEIRTRYNRISVLVNNAGTYEKNRTLTPD
                     SIERTFAVNYLAPFILTHELLPLLKRSAPSRVVNVASIAHRDVREIDWNNLQGEKNYD
                     AFGAYALSKFADITFTYTLSERAGTSRITVNCLHPGVIATKLLHAGFPGIRGKPPSEG
                     ARIPLFLALSPEAAGITGKYFEENIRPVPSSALTYDKDVRSRLWKVAEDLTWIGKEL"
     gene            complement(8508..9191)
                     /locus_tag="PK679_06090"
     CDS             complement(8508..9191)
                     /locus_tag="PK679_06090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HPC55560.1"
                     /translation="MEVFVGTSGWSYDWNEGGNLDWYIQNSGLNAVELNASFYRFPFR
                     NQILGWSRKGRELAWAVKVHRGVTHTHRFNEAAGVLWKRFREAFIPLDPFVDFYLFQA
                     HPRFSDPDILLRFAESCGLGRRFALEIRNPDLLGNAPLYKRLQEVVTLVSVDSPVVQN
                     RIFEGDCIYLRMHGRRGWYSHDYSDEELEKTAGTILDLSPRRVYVFFNNDHAMLGNAR
                     KMKKVLTSL"
     gene            9443..9637
                     /locus_tag="PK679_06095"
     CDS             9443..9637
                     /locus_tag="PK679_06095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55561.1"
                     /translation="MKDIVATRRMENGIACYYGEKGKEEFETFNYNELIDMKINALDL
                     LNDPKNYAVDPVNHKVVMKK"
     gene            complement(9875..10801)
                     /locus_tag="PK679_06100"
     CDS             complement(9875..10801)
                     /locus_tag="PK679_06100"
                     /inference="COORDINATES: protein motif:HMM:TIGR00367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HPC55562.1"
                     /translation="MLLPFLLFIAGLLLLVKGADITVDGAKDVALGMGLSPLFVGTTV
                     IAFGTSLPELVVTTEAFSLGNFSVGMGNIIGSNIANIALILGICALVRPDAISRESGK
                     MNVQRDMVIMILATGLFILFSLRATLDIITGIVFLTCFSLILIRLPRLEEKPDAVTCT
                     PRPLKYSLAITVLGIFLVITGAHLLLAGAVDIARLFLVPEFLIGFSLVAIGTSLPELA
                     TSVAATLKGSIDLAVGNVLGSNIFNLIFILGLNSLFFIIPVPVPWNLVILLAFSLAVL
                     ILVFQQSAITRTWGAVMLGAYVGCIMMLFGFS"
     gene            10965..12026
                     /gene="corA"
                     /locus_tag="PK679_06105"
     CDS             10965..12026
                     /gene="corA"
                     /locus_tag="PK679_06105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HPC55563.1"
                     /translation="MSRRRKIPIRPGLSPGTLAVDGKHTKGPVGITVIDYDATHFSEK
                     KVSAVEECYPFRDTGTVTWINIDSLGNTEVIEKLGNHYNIHPLILEDILNTGQRPKIE
                     DLDGYLYVNLKMIRLVGERKEILIEHVSLIMGSNFLLTFQEDTGGDVFDPVRERIRKE
                     GRIRKFGPDYLAYALIDDIVDHYFLVIEHLEEVVEDLEEEIVRNATPALLHKITALKK
                     KMITLRKSIWPLREVISGLERSDSPLVKDSTRIYLRDVYDHVIQVIDTLETIREMLSG
                     MIDIYLSSLSFRMNEIMKVLTLIATIFIPLTFVAGVYGMNFQYMPELTWEYGYYTVWG
                     VMISIVAIMLVYFRKRQWI"
     gene            12090..12770
                     /locus_tag="PK679_06110"
     CDS             12090..12770
                     /locus_tag="PK679_06110"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
                     /protein_id="HPC55564.1"
                     /translation="MEILLAIVLAVAPGIFWLLFFYSRDRYDPEPPVWVMLVFLLGGA
                     VTFPIGILEGSLLAISGGFLGSVLIAPVFEELAKYWVVEKTVYRTHVFDEPVDGIVYA
                     AAAGLGFATLENTLYVLSALDESFLFALQTAVLRGILSVPAHVLFSVMWGFALGVSQG
                     GSRRRHDPIVLWGLCLAVGAHALFNLLLVSGTGIPVLLLFLVPLLWVVTINRVRDALA
                     LSPFSGRW"
     gene            complement(12872..13489)
                     /locus_tag="PK679_06115"
     CDS             complement(12872..13489)
                     /locus_tag="PK679_06115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="METTL5 family protein"
                     /protein_id="HPC55565.1"
                     /translation="MKLKQLERDLSGLEGFEKPSSHREQYTTPPDLAARLLYHAYMRG
                     DIGGRRVCDLGSGTGILAIGAALLGASSVTGVEIDPDAIAVAALNAARKGVSPVFIQG
                     DINDPGLVDRVGPMDTVVMNPPFGAQNPHADRPFVNAALVIAPVTYGIFNRGSLSFLK
                     GFVEGRAEIEGVIQGTLPLKRQFFFHRRDRKEIPVEIVILRRFDR"
     gene            complement(13496..14437)
                     /gene="dph2"
                     /locus_tag="PK679_06120"
     CDS             complement(13496..14437)
                     /gene="dph2"
                     /locus_tag="PK679_06120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043364 - glycyl-radical enzyme activating
                     activity [Evidence IEA];
                     GO_process: GO:0017183 - peptidyl-diphthamide biosynthetic
                     process from peptidyl-histidine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphthamide biosynthesis enzyme Dph2"
                     /protein_id="HPC55566.1"
                     /translation="MTGYSELAGELRRRNVRSIALQFPEGMKRKAREIALFLRKEGFS
                     VIVSADPCYGACDLASDALRLVDALVHFGHTPLGDPDPKVIFEPVSVDFDPGVLKGAV
                     HHFRKSTIGLVTTAQHVHLLPAMVRVLADSGIGAVTRPGSRGCSEGQILGCAFEAARI
                     PSVEEILYVGTGIFHPLGVRLATGKRVIALDPLTGTAREVDEDRFLRKRFALIEKARS
                     ADAFGFIVSSKTGQNRLSLAREMASGCPNAVILLMREVDPGELLNLGFPAYVNFACPR
                     LAYDDQPRFPAPVLTPQEFRILTGETDFSSYTIDEMQ"
     gene            complement(14421..14969)
                     /gene="hpt"
                     /locus_tag="PK679_06125"
     CDS             complement(14421..14969)
                     /gene="hpt"
                     /locus_tag="PK679_06125"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine/guanine phosphoribosyltransferase"
                     /protein_id="HPC55567.1"
                     /translation="MLERLIASLENAPIVKRGEYNYFIHPITDGVPEVDPALIREVCT
                     ALVKVLDLDGVNRIIAAEAMAIPIGIALSLVTDIPVNIVRKREYRLPGEVAVHQATGY
                     SKGQIYLNGVRKGDRVVIVDDVISTGGTTRALLWALDQAGATVKDVCFVIKRGKPDIG
                     RSYKTLVSVEVTDRVRVIDRIF"
     gene            complement(14962..16059)
                     /gene="mfnA"
                     /locus_tag="PK679_06130"
     CDS             complement(14962..16059)
                     /gene="mfnA"
                     /locus_tag="PK679_06130"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase MfnA"
                     /protein_id="HPC55568.1"
                     /translation="MREKGRSIDDLFSFLSAKRQEDVSHEYILSSMCTIPHPVASRAH
                     SLFLETNLGDPGLFPGTASLESLLIERLGTLLSLPAAYGYATSGGTESNIQALRIAKR
                     LSGSRTPNVVVPRSVHFSFQKACDILDLEMRTVPLDREFRMDAERVPELIDRNTCALV
                     GVAGTTEYGVVDPIRELSSIAADFGIFLHVDAAFGGMVLPFLDDAPPFDFSLPGVSSI
                     AVDPHKMGMSTIPAGVLLIREKDAFSSLAVDTPYLSVRQEFTLSGTRPGGPVAGALAV
                     LEYLGKEGMRDIVAGCMKNTWRLIDGMEAFGIPRIVTPDVNVATFAKTNVPAPWRVSW
                     TREGHLRIVCMPHVHAGIIESFLKDIGDIHA"
     gene            complement(16052..18328)
                     /gene="ppsA"
                     /locus_tag="PK679_06135"
     CDS             complement(16052..18328)
                     /gene="ppsA"
                     /locus_tag="PK679_06135"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HPC55569.1"
                     /translation="MREMPDILWLEEIRKEDIAAVGGKGASLGEMSAIGLPVPRAFVV
                     TSHAFRQFLVETGLEKTLFSELERLDVENSAELENAAEKAKQAVLKAKMPASIKQKIR
                     DAYRKMDNGRMVVAVRSSATAEDLPDASFAGQQETYLNISGEKNLIDAVQRCWASLYG
                     ARAIYYRAKQGFDHRSVNIAVVVQELVRSEKAGVMFTSHPVTGEDVSIIEGSWGLGES
                     VVSGSVSPDKYVFDMRTGKVVDRLISNKRFQIVSDGDHGTKTVEVPKELQDAPLLSDE
                     EVAKLAKYGKIAENHYGVPQDVEWAIVGNTIYILQSRPITTIRTGKREESGAGRAGTQ
                     TIILKGQGASPGIASGRVVIIHDARDAGKVKEGDILVTRMTNPDMVPAMRRVAAIVTD
                     EGGMTCHAAIVSRELGTPAVVGTKTATQVLKPGQLVTVDGEKGFIYEGEVDIPREKPE
                     KVVSAGFAPIITATSVKVNVSMPEAAERAAATGADGVGLLRIEHLILGLNKTPGWFIA
                     NGREEEFIQELYNGIKTVLDAFYGKPVWVRTLDAPTDEFRNMAGGEDEPVEHNPMLGW
                     RGIRRDLQSPDQFRLQVEAFRRLWEQGYDNLGIMFPMVSHPSEFIRAREMMRKWGVDV
                     DKVTLGVMIEIPSSAILIEDFIRAGIRFASFGTNDLVQYTLAIDRNNQNVASMYEPKH
                     PAVLALIDSAIRCCRKHGVEISICGQAGSEPPMVRWLVEHGITSVSANIDAIAKIRET
                     VARTEQQIILENARSRNA"
     gene            18501..20105
                     /gene="serA"
                     /locus_tag="PK679_06140"
     CDS             18501..20105
                     /gene="serA"
                     /locus_tag="PK679_06140"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004617 - phosphoglycerate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HPC55570.1"
                     /translation="MADFKILVSDPLADEGLEILRRECSVDVKTDLTEDQLVQIIGDY
                     DALLVRSGTDVTARVIEAGKRLRFIGRAGAGVDNIDMEAATKKGIIVANAPEGNTLAA
                     TEHTMAMMLSLARNIPQANASLKKKEWKRSKFMGVELNEKTLGIVGLGRIGREVAKRA
                     QAMGMHIVGYDPFITRDRAAQMGVEAVSLEELFKAADIITVHTPLIKETRHMVNEKTI
                     AMMKDGVRIINCARGGIIDEKALYNGLKSGKVAGAALDVFEEEPPLNSPLLELDQVIV
                     TPHLGASTIEAQKNVAVSIAKQCISVLKGGSAKYVVNAPMIPPEHADTIEPFASLAEK
                     MGRFLTQLVSGRMEKVEIIYGGELATLGNNTRFITLMALKGLLDPILQVPVNIVNAEL
                     IAKERGISVAETMTRDSGGFKSLVTIRVKTDTMEETMSGTVFMKGRSRIVSIGGYTMD
                     MIPEGYVIVSRHLDKPGVIGRASTILGKGNVNIAGMQVGRIRPGEEAIMVLNVDSEVT
                     PEMMEEIRSMPGIFTAVFAKISDTLI"
     gene            20286..20359
                     /locus_tag="PK679_06145"
     tRNA            20286..20359
                     /locus_tag="PK679_06145"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20320..20322,aa:Val,seq:gac)
     gene            20498..20914
                     /locus_tag="PK679_06150"
     CDS             20498..20914
                     /locus_tag="PK679_06150"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55571.1"
                     /translation="MLSLLYVDDKPEFLDLVKLFMAKRGRFSISTCQSASEAIKDLSM
                     NRYDVIISDYYMPGMDGLAFLRTIRGMGDQTPFIMCTGFGGDSEEKEALGAGADFYIV
                     KGGDSGIFFDLLCRAVSTVIRNKGERIGPDSARGPQ"
     gene            20932..21345
                     /locus_tag="PK679_06155"
     CDS             20932..21345
                     /locus_tag="PK679_06155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF61 family protein"
                     /protein_id="HPC55572.1"
                     /translation="MYDESALRRWMGLEMRKINEGVADTRVSLHALLMMEKPVTVTKG
                     GQEYRFDKRVLEDIASRLPVVLQKKLRLPVIFYYDMEVPTSCFLSDRVAFEALQEMGE
                     LSRERVWEGGRVFVGRAIVFALMRSYPTVFQIMMR"
     gene            21445..21822
                     /locus_tag="PK679_06160"
     CDS             21445..21822
                     /locus_tag="PK679_06160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55573.1"
                     /translation="MNGGILIVEDDPVISQLIGWRLEKMGFFVSGKTPTAEEALDKIK
                     DGRPDLILIDINLPGTMDGTELARTIKEQFQIPFIFLTAYTDSETISRAIDTEPAGYL
                     IKPFKDEELKVMIELALRHAKKG"
     gene            21902..22669
                     /locus_tag="PK679_06165"
     CDS             21902..22669
                     /locus_tag="PK679_06165"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55574.1"
                     /translation="MGFILKSACFFLFLALVLQPAISAADDCGCGGGGTTGDSSDISS
                     GGYGSSEDPMIHLVRAREFLSRGDLPMAMAECRESLTLDPHNVQALLLEGEILFRMGR
                     YGEAAEAFRKVTGMYPSEEEAYTRLGNTYLLLGDYRSAEKAYTRSLAIRPNDPVVREN
                     LEKAVRLSGQENPSPGKEIFENGTVTGTAPRTRAESPEPAELTTPREEKAVPLSSRTP
                     TTDLSPVPFLIALVVTAFITRSEKKGSKTILSLKGLG"
     gene            22666..23199
                     /locus_tag="PK679_06170"
     CDS             22666..23199
                     /locus_tag="PK679_06170"
                     /inference="COORDINATES: protein motif:HMM:NF015239.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017111 - ribonucleoside triphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphatase"
                     /protein_id="HPC55575.1"
                     /translation="MKEGTTNILITGPPGCGKTTLIKNIISDLSFLSPVGFYTEEIRE
                     GKMRVGFRGVSLDGRTFLLARSGFSSRFRVGKYGVDKAGFESFLATIPFQDAGFVVID
                     EIGKMECISGQFCHLVEDLLSSEKCLLATIASRGTPFIEAIRQRDDVEIHLIDRKNHM
                     DIAGRVKERIRALIERT"
     gene            23323..24672
                     /locus_tag="PK679_06175"
     CDS             23323..24672
                     /locus_tag="PK679_06175"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011450003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HPC55576.1"
                     /translation="MKSVILAGGVGTRLWPLSRTYNPKQFLKMNGTSLFQETYKRAMR
                     LSKPEDIYVVTHRDHHYLALNQIEELNQNVPDGRILSEPVGKNTLPAITWAILEIEKE
                     SGESLVAVFPSDHYLGEDAMDEIAAAGRIAGDFLVTFGIPPTHPHTGYGYIAPGDPLS
                     LGFRVSRFREKPDWETARVFVDAGYLWNSGMFLFSTNTFLGELERLQPGIYVPMREKG
                     VASYPELPSLSVDYGLLEVSDRVAVVPLRARWTDLGTFRAWYDFKQHDSHGNAGEAEF
                     IDSEGNFVHAPGKKVALVGVKDLVLVDTGDALLACRMDMTESVGNLVKVLKNRGDTIT
                     DYHLQVHRPWGSYTELERSRFYRIKRVTVKPGKKLSLQMHHHRSEHWIVVSGMADVIL
                     GDRTIHLRQGESTFVPAGIRHRLANTGKIPLEVIEVQIGEYLEEDDITRFADDYNRI"
     gene            24819..25865
                     /locus_tag="PK679_06180"
     CDS             24819..25865
                     /locus_tag="PK679_06180"
                     /inference="COORDINATES: protein motif:HMM:NF021416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2117 domain-containing protein"
                     /protein_id="HPC55577.1"
                     /translation="MSPLAKDTVMVVHGAEIFDTGNAAWLFSVLAPCRIVVAGIMARV
                     AAEEFGLPCEFADIPPSMVMRRLHQPCFLANRGKSPESGRIFGEIVARRVGDEGIIHV
                     ECASGEVICWNRYPDDLAREIATLTGYSLVSGVTMPEGTEPGTRVIRGCLPGEAVFVN
                     GTVIGVATGREVVIRVSEKGVEPVLGLSVKVHGLEKLNKSGPIDPATAWCKSGPIRAR
                     EPVTTNNAPPKKGRVVFIDHCGHTLYRSVSSDGVCGIVSVGDDTTAVCAHIGAHLGVP
                     VFGIVDGDTDGIVPVRYAPGSVIAVATGISDDDLGKEVAVMIPAEEVDWDDFIRMLVA
                     RIGDRARICRPPHS"
     gene            complement(25875..27560)
                     /locus_tag="PK679_06185"
     CDS             complement(25875..27560)
                     /locus_tag="PK679_06185"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA ligase"
                     /protein_id="HPC55578.1"
                     /translation="MKFLEFARICEQLEGIGGRLEMTGKISAILPSLDEGDLPIFVRF
                     LTGRIFPDWSPNKIGIGPNLLFDALTQVVDATRSDIIGEINRKGDVGLAVQAILENKR
                     AGKRSGRSPTFQTSLFSQELDLSSVYSDLERISRLEGRSSQVEKLSLVQNLFQNASPL
                     EAKYLARLILEDLRIGVGEGTMRDAIAQAFSVDPSLVEHAYQAINDLGEVALRARKGR
                     DSLADVHIRLFHPVKMMLAQQGSISQAIAENGAMAAEYKYDGSRFQFHKQGNRCRMYS
                     RKLEDVTEALPEVVETLKNATSHDVILDGEVIAIKDGRPLPFQTVLRRFRRKYDIAAM
                     QKEIRMQPFVFDILYLDGKTLIDDPFRERRKYLEEAMSGCVAPQTVSSDISVIEAVYR
                     ESLDAGHEGLMLKVLSSSYTPGIRGKNWLKIKPGVDSIDLAVIGAEWGEGKRAHLFGS
                     FLLACQDRGELLPVGKVATGFTDEELQEVYELLKDRVISESGKEVHLEPFLVFEVGYS
                     EIQKSPNYESGFALRFPRFIRVRDDKGISDIETLDSIRERFQRQSVQGKPGGE"
     gene            27710..28903
                     /locus_tag="PK679_06190"
     CDS             27710..28903
                     /locus_tag="PK679_06190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55579.1"
                     /translation="MAGEWVPDALIEQKMGQTKREMMDYIEKNSEKIDSNLPVFFGHV
                     ISILENNFPDIPDQVYDRFIDDVTVKVLEESKRSTDVEYIERLFRHATRVKRKYTGRA
                     IFDIVLGLKLIDIGKYKDAIDILMKYRTVDAIVCTAIAFCYYELSALELPPDQRPDKS
                     TTSSMALSAREQMIELARLQPPVNRLRFPQVIQELRVNKIFWFMIKLAIDWFPDQPVY
                     LKIGLEKAKKDQNRDMRGELLKIAAERYYSDMFFLRDLYHFKLEARDAGGATAVVRQM
                     MQQHPDELEPLYYGLQLAIMSSQDSAYQKFRSTAISKKMPAHVILLLDLAFFLISGRR
                     TDAEVMFEDMEKKLPALGYYLEVLDYLMQDIFSEDEKRSKTARKVFMDSIDQYCLKLI
                     KMKED"
     gene            complement(29117..29905)
                     /locus_tag="PK679_06195"
     CDS             complement(29117..29905)
                     /locus_tag="PK679_06195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC55580.1"
                     /translation="MRCISLASGSKGNCLFIEGESSSLLVDAGLTRREILSRLHAAGK
                     TTDSLAAILVTHEHIDHIAAVMPLARHLSIPVYATGGTLVDLLDSGGVHRKPVRAVRI
                     DYGEDFCVGEFSVRAFAVSHDAREPCGYTIRNGDQTLGCCTDTGMVTDHMIEHLSRCD
                     GLVLESNHCPHMLKEGPYPESLKRRIRSRRGHLSNNAAAECIKGLCTQVHSVLLAHLS
                     EVNNTPEKALACAREAAGLFYSDLEIRVATNAGSDAGWPHGIFL"
     gene            complement(29996..31084)
                     /locus_tag="PK679_06200"
     CDS             complement(29996..31084)
                     /locus_tag="PK679_06200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55581.1"
                     /translation="MIRFDHVCKRYGEKEVLSNLSFEVRKGEVFSLVGPSGTGKTTIL
                     RIIAMLDNPSSGTVMVMGKDTRTPDALRVALRRQMGMVFQKPAALRGSVADNVALGLK
                     FRKFAPEDISRRVSEVLDLVGLSGYEGRRTNTLSGGELQRVAIARALAPGPRLLLLDE
                     PTANLDPVATEKIEDLILSLNEKSGITIVLSTHDMAQAQRLSTRIAVVLDRKICQLGN
                     PFQIFYQPVTREVARMVGIDNILAGEIVANEGGLASIDVSGVILHAPSPLDPGTRVTL
                     FVRPEDLFIGKDATAGRSSPRNVLPATILRLIPQGPNTRVTVDAGVRLTGVITRQSCQ
                     ELGLSPGMTVSVSFKANAVHVVPVEKAG"
     gene            complement(31086..31772)
                     /locus_tag="PK679_06205"
     CDS             complement(31086..31772)
                     /locus_tag="PK679_06205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55582.1"
                     /translation="MNEIIDGFVQAFSLIISLDPEVLEITARSLLISLAATAVASLVA
                     IPLGGLIHFREFGGKRGLITIIQTLYALPTVVAGLFVFLLLSRTGPLGFLGLLFTPVG
                     MVIGQAVLIVPVLVGMTLVALSGVKRAISDEIVALGATQTQAILTIIREARFAIIGGI
                     ILGFGRAISEVGAAMIIGGNIRGYTRVLTTAIALETSMGNIALSIALGMILLGIAMVV
                     TVALFIVQER"
     gene            complement(31794..32804)
                     /locus_tag="PK679_06210"
     CDS             complement(31794..32804)
                     /locus_tag="PK679_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HPC55583.1"
                     /translation="MNMHFLSTLHGGTVIFLVALVLGAILISGCTTTNPGQDGAQIPP
                     TTQSPSFPPHNGQKLILATTTSLYDTGLLDYLEPLFEEKYGVDLLITSQGTGKALEIA
                     KRGDCDILAVHSPDQEKAFMDGGHGINRRCFAYNYFIVVGPADDPAGIRGMAPQEAFR
                     TILGKGKAGNPGVFFVSRGDNSGTHSAEKNIWKASGYNYTSEVQRSGAWYIEAGKGMG
                     ETLQLASEKGAYTLTDEGTYLAYRGKLNLVPVIEEGDILLNVYSVITVHAKNQPVEKI
                     TMANNFVNFLISPGIQAKIGEYGKEKYGKGLFIPMNGGCMRFECDCTTPASETGPLTS
                     FK"
BASE COUNT         7673 a         8780 c         9070 g         7463 t
ORIGIN      
        1 ggataaaagc tgaaagcatc taagcttgaa acccggccta aaaagagact ccgttgagga
       61 catgggtaaa agacccgctt gataggcctg ggatgtacgc acgaaggcaa cgacgtgttc
      121 agtccgcagg tactaacgtc caaaccccca gtgctcgcac tcgtcaaacc cagacgaaat
      181 ccttgtgtgc aaaccaataa gccttatgtg ctattctgat gaatagaata aggcaaacac
      241 ggctgccaag gtggcggagc ggctacgcgg ttgactgcag atcaactaca ctccggttca
      301 aatccggacc ttggctttgg gtgatggcgg ccacagcagt cgggaaacac ctggactcat
      361 tccgaaccca gcagttaagc cgactcacgt aggctgttgt actgaggtac gcgagtcctc
      421 gggaagcatc cttcgctgcc atcacccttc ttgcttttca aactgtctta ccggagagcg
      481 gatgcttttt tcatctcaat tgtatcgttc cgatggatac cggcaggctt ggcgggatcc
      541 gtgatagaat catttcttca ggcaatatga aagagaatct gaaaaatgaa aaaacgaagg
      601 aaaatctcat tttaagtcac ataattatca aaccggatta tagggaatgg atatttacag
      661 ttgtacgtga tgaagaacaa tatcactcca tgacaacacc cattaatctc caaggttgat
      721 aatcgcagat aattctgaca ggatgtgcat ccattcattc ttgactttga caccccattc
      781 tctccttttt ataaagtctc atttcgattt catgagtagg atcagataat atgctccccc
      841 gagtcattct ccatagcgca acaagcctgg acggtcgtat cacggacttt cccgccaatc
      901 ccgatttgta ttatgccctc gcggcgacct ggaaccctga tgttgttctc tttggcagtg
      961 aaacgatact tgcagcgtta cgggacaatc cttctctcgc cgtgccttca gagcatgaag
     1021 aaattttcag accaccggaa ggtaccaatg atacccgtcc tctcatggtc attgccgaca
     1081 gccgggggag agtgaggtgc tgggatgcta ttcggagatg gccgtacatg cgggatcttc
     1141 ttgcgttctg ttcatccgcg accccgaagg attatttttc ctacctcgaa gagcaaaaaa
     1201 ttccggcgat tgttgccggc aaagaccgga ttgatatgcg gggggccctc gggatgtaga
     1261 gcttccaata tggagttgag actgtccgcg tcgacagcgg ggggacgctc aacagtgtgc
     1321 tccttgcagc aggcgttgtc gatgaggtga gcgtgctcat ccatcccttc cttgccgggg
     1381 gcagatcgga gttgacaatg ttcgatccgg gaaaggcagg attccctgat ctccaaatcc
     1441 cactcaccca tattaaaacc gggatggtgg gggatggtat tatctgggcc agatattcgg
     1501 ttcagaaata gtgaatgagg gttgcatggg taaatttgga aattcattac ccctaagcaa
     1561 caggtacatc ttcattaatt atggccggat gaatgaacct tgtaaaactc atccaataca
     1621 cgaatgacga agatagtaga gacctattcg aggaaacagg gaatccttta accatataac
     1681 tcttcgatcg tgatacgaca gtacgagaaa atgcaaataa cgggattggc ctggaacact
     1741 gtttaaaaca tccattcacg aatcacgaga acattattca tgatcgattt ggaatgcagc
     1801 ctaattctcc ggggagattg aaagggatga acggggactt cggcaggaga cgaagaagaa
     1861 agtgtggacg gggtgcagcg ggaaagattt atgttttcgg cattctggaa cgaggaaaaa
     1921 aggtgaatgt ggaggtcgca gccgatatcc ggggtgatac ttttctggaa ctggttttct
     1981 ataaggtgaa acgagggaat ctcatccata tcgattaatt tcaaagttac aatggactgg
     2041 ttcctttagg ttcaaaaaac ggagaatcga tcatggaaaa aaaaaaattc gccaatggaa
     2101 aagagtgcat caccgaaatc gagggggaga tgggcattcg cgaaggaacg gttgttgaaa
     2161 tatcatggtg tagatgctga atcattcctt ctacctcaaa gaatcggagt tccggtatac
     2221 ccatcttgac tgagatattt ttgaggatat tgtcgacgtc ctggctggat agagtcacgt
     2281 gggtaaaact gagtaaatcg cctgaatttt tttcacatct caatcgaggg agaatgattc
     2341 aggtagttca tcaatagcta tcctgtggtg ggaaaacacc cgtacattcc gcagttcctc
     2401 ccgtaaatct ctccagatac cctgagcaca ggcggtatgc tccgattacc ttttccgggg
     2461 atacccccgg tacaccgcag gttacgagat ggatgttttt cgtttcccgg gttactttgg
     2521 tcgcatccga gtccctgtag ggataaaccg cgatgacact cctgccatcg tcaatgacga
     2581 cctggttctg acggagcagg atgggttttg gcatccctat gcccagaaac tcttcccctt
     2641 cccgggcaaa tctcatggtg agatccccct ccagcctgtc cgcgtcaaat gccgcaatcg
     2701 ggatgccagt ttcggctgat gcaaggttgt acatgttcac gaccgggttg atcaggggga
     2761 gatcctttcc ggacaggatc ctcctgacaa gtgcttctga tgcaggacgt gtcttcgtag
     2821 ggtctacccc gactctccag aagaaatccc ggtatgccct gaagaggggg tcgtccttta
     2881 cctgttccag ggtatagcgg gaccgtatcc tgattacgat ctcttccctg agtgcatcga
     2941 accgggggat ttctcctgta ttatcgatgg acctgatcgt cccttcgaca acacagagac
     3001 cgggaaaggc ggccggtata tccttgtgaa agtccatgca taccttctct gaattgtgct
     3061 aaaaatactg ttctgttctg atgagtgatg atggggttag aaaatattga ttcaccttcc
     3121 gattcttcac ggattaatca aaaattcagg gaacagtttt ttatgttaaa ttgcccggtc
     3181 ctttcctctt cttccaatca tgaaatcacg atgaaaggag cgttattttt atattggtta
     3241 tcagataata taacgcccgg aataaaagag agaggtgcag ggaaatgcca actgatcctg
     3301 tctgttacat ggtagtcgac gaggatgaag cgaccatccg gagttcatac cgtgggcagg
     3361 aattcttctt ctgctcggag ttctgcaaaa agaagtttga ggaagatcct gcccggtatg
     3421 ccagacttgc ccggtcactg gatatcgggc ctgatatcag ctgttaggaa tatctccccc
     3481 ttttcgggct ctcatggttt gtgggcttcc acttccagcc ggaccatcct gacatgaaca
     3541 aggccttttg aatccggtgg atatcgttca agatacgatt ctgcaaggtc agagatgaag
     3601 cgattcctcc cggaaacggg aaccctccct gtatagggaa gccacgttgt ccgaatccat
     3661 cctgagagcc cttcttttcc tgcctgaacc atgtcttttg ggatcagttc cgccctgatc
     3721 ggaatgaggc ctgcgtcccc gagcagcacc ctgtactcac cggccgtgaa gaaacgatag
     3781 gggttcgaaa aatccatgaa atagtctttc cagggatccg aatggatcat agcgtcagcc
     3841 aggttcagga tatcgctcgc gttcccatga ccccccatct ggaagaagac ccttcccttg
     3901 cgtttcaggc atcggaagac tccccggagc atcctcgcat ggtccggaac ccagtgaagg
     3961 gctgcatttg agaatacaag atcaaactgg tttataaatg ggatatccag tgcgtccatt
     4021 tcaagaaacg tgatgtttgg agtcagggag cggggatact tttctctggc aagtctgatc
     4081 atggatgctg aattatcgat agctgttaca ctcccctgcg gaacgcggga ggcaaggagg
     4141 gccgtgactt tcccgtcgcc gcatccgata tcgagaatgg attctgttcc attcagatca
     4201 agtttcccga tcatctcctc tgcccaccag tactgggccc gggaatgcgc cgcgtaatca
     4261 gcgggattcc actcatatcg ttccatgatg cggttctcca agggattcgt gaacgtttac
     4321 ggaaaaaata tgcagagcag gaaagaagaa tgtttggacg tacgggttcc acccccccct
     4381 caatgacttc caaaaaatcc gcagtcatcg tcaggtttaa tccccgtggg tcacaagacg
     4441 catgcatgaa ttcaacccct gcagccatcg ccgcactggc atctttctgc atgcttgctt
     4501 tagtccttgc cgggtgtacc ggcaccggaa taccaggccc ctcccctcat ggtcagacta
     4561 ctgctccatc cgtatcggag acccctaccc cgtccacgac tttccctgcc agtcacggtt
     4621 ttgaaaaaga tgttgttgaa gcgaataacc ggtttgccct tgacctttac acccgtctcg
     4681 cagacgatcc tgcaaaccgc aacgacaatc tcttcttttc gcccttctct atctcatcag
     4741 cgctcgcgat gacctgcgaa ggagcacggg gaaccaccgc cggagagatc cgctcggtat
     4801 tccatttccc ggagaaccag agtaccatga gatccgggtt tgccgaaatt attgcgggca
     4861 taaacaacaa gacgaacgca tacacactcc ggaccgctaa cgccctctgg gcagaaaaga
     4921 catatgcctt tctcccggac tatatcaaca ccgcggaaag gtattacggg gcccgcgtaa
     4981 cgaacctcga cttcgtgaat gcacccgagg aagcacggat cacgataaac agatgggtgg
     5041 agggtcagac agagaaccgt atccgggacc tcattccaag gggagtcatc gattcacaaa
     5101 cctgccttgt gatcacgaat gccatctatt tcaagggaac gtggaaaaag cagttcgaga
     5161 aggagaagac gacagatgca gtgttccgga cggccaacgg ttcagccgta caggtcccga
     5221 tgatgcagcg gacggacgaa aatgcgacgt ttggatacat ggagacggaa acataccagg
     5281 cactctcgtt gccatacgag tcaggcggga gccgggacat ctcaatgctc ctcattctcc
     5341 cgaaaggtga ttcacttgca gagatcgaac gctctttggg tcctgatatg tacgatgaca
     5401 tttgtcatcg tctcgtggaa aaacgggtca aagtcttcat cccgaggttc tcgctcaaga
     5461 ccaggtactt cctcccccgg gtgctctcgt cgatgggaat gccccttgcc ttcactgccg
     5521 gtgccgattt ttccggtatg gacgggaggg gaggtctctt cattacgaat attatccacc
     5581 aggcattcgt cgaggtgaac gaagagggga ctgaagcggc tgctgcaacc gcggttattt
     5641 tgggcaaggg gatatcaccc cctgaagaaa aaatccccgt tttccgggcc gatcacccgt
     5701 ttatcttctt catcagggat aacgaatccg ggaatatcct tttcatgggg cgggttgaaa
     5761 atcccgtctc accctgatcc ggtttttacc ggaaaaggag aacgccgccc aacattacgt
     5821 tcactcccct tttttccggc atggcagggc cctgtttgat atgcggggtt tttgcatcgc
     5881 gggatagcag gtatttgacg ggtttgcgca ggtcattttt attcgatcag acctttttta
     5941 ccaaagccct ttttacgagg ttatttatgc cgcgggagcg atctctcctg aactgcatga
     6001 aaaaacaccg cattgacctg aaagccattg cccgcaaggt aatggaaaag tatgggtttg
     6061 tttccgattt tccacccgcg gtgataaggg agaccagctc aattgaagag gtacaatcca
     6121 tcgagccgga caaagacacc cgcgacctcc gatccctcct ctggtcgtcg attgacaaca
     6181 gcgattcaga ggatctcgac caggtggagt actgcgaatc ccggtccgat ggggagatac
     6241 gcgtcttcgt tgccatagcg gatgtagact tcttcgtgag gaagggttcg aataccgacc
     6301 gtcatgccgc gttcaatgga acctcggtct acctgggggt agagacattc cccatgcttc
     6361 cggatcacct ctccaaaggt gtctcctccc tcctcccggg gaaagaccgg agggcagttg
     6421 tcatcgagta cactgttctt cccgacggca ccgtgaaaca tggggctatc tttcgtgcaa
     6481 tcgtgaagaa ccatgccagg ctcgtgtacg aggaggtcgg agactggctg gagggaaaag
     6541 cacctattcc atccggtgtt tccggcgttc ccgggctcga ggaacagata aggctccagg
     6601 cagaggttgc ccgccggttg cgcgcccaca ggatgaaaca gggagctctt gacctggaga
     6661 cgatcgaggc gcaacccgtg atggagggcg gggccgtcag gggactcgtc atccaggaac
     6721 agaacgcagc caggcagatc atcgaggagt tcatggtggc agcgaacggg acgatggtgc
     6781 atgtcctcgg ggctgccggt gtccccatgg tccagcgggt cgtgcgggtt cctaaaaact
     6841 gggatggtat tgtcaggacc gctgcacagt acgggttcca tttggcaggt gaaccggatt
     6901 caaaggccct ggcacggttt ctcgacacga ggaggcgtgc cgacccggaa cggttcccgg
     6961 acctctccct gacaatcgtg aagctcatgg gaccgggaga atatgttccc tttgtaccgg
     7021 gagacacgcc catcgggcac tttgcgcttg cagtcctcga ttatacccac tcaacggcac
     7081 cgaaccggcg gtacgtggac atcatcaacc agcggctcct gaaggcagtc ctggatggaa
     7141 agcccatgcc ctattcggct cacgaactgg caggactcgc cgaacacctg actgacaggg
     7201 acaaggcagc ggagaaagct gcacgtttca tgaggaaagt agccgcagca gtcattctcc
     7261 gggaccggat aggccagaca tttgatgcaa tcgtgacggg tgcagccgac aagggcacgt
     7321 atgtccgtct cttcgatccc cctgcggagg gcagggttgt tcagggagag agaggtcttt
     7381 tcgtgggaaa caaggtaaag gtcaggctta ttgacaccga cccggaactc ggatacgtgg
     7441 actttgcatg cgtcggaagg gataagcgat agggggataa cgttcatctc ccgccccgta
     7501 ccacctttcg cacatgccag caccagtcat cctcgttaca ggttccacgg acggaatagg
     7561 caaggccatg gtccggaagc tggcagactc cgatgctgaa atcatcatcc acggaaagga
     7621 cagtgtaaag ggcagggaaa caatcagaga aataaagggg ctctcgtgga accggaacat
     7681 tgacctcatt atcgcggatt tttccatcca ggaggaggtc cggagaatgg cagaagagat
     7741 caggacccgg tacaaccgta tctctgtcct cgtcaataac gcgggcacct atgaaaaaaa
     7801 ccgcactctt actcctgatt ccatcgagcg gacgtttgcg gtcaactacc ttgccccatt
     7861 catcctcaca cacgaactcc tcccgctcct gaagaggagc gcaccttccc gcgtggtcaa
     7921 cgtagcctcg attgcccacc gcgatgtgcg ggagattgac tggaacaatc ttcagggaga
     7981 gaagaactac gacgcatttg gtgcctatgc cctctcgaag tttgctgata ttacatttac
     8041 ctatacactg tcggagagag ctgggacaag cagaattacg gtaaactgtc tccatccggg
     8101 ggtcattgcc acgaaactgc ttcatgccgg attccccggg atccgcggca aaccaccctc
     8161 agaaggagca cgaatacccc tctttcttgc cctttcgccc gaggcagcag gtattaccgg
     8221 aaagtacttc gaggagaata tccgcccggt tccttcctct gcgctgacgt acgataaaga
     8281 tgtccggtca cgcctctgga aggttgccga agaccttaca tggatcggga aagaacttta
     8341 aggagaagtc cgggaaagga ttaaacgata gaaaaataag caacccgcag ctccagatga
     8401 agcacaaagc ccggaagaaa cggggatatg cacgtagtag gtagcaaagg atatttttct
     8461 tcctgcaccg ggtgggggga atgtcgcggg cacatccctg aaaattatca aagagaggtc
     8521 agtacctttt tcatctttct cgcattccca agcatcgcat ggtcgttatt aaagaacacg
     8581 tagactctcc ggggggagag atcaaggata gtccctgcag tcttttccag ttcttcatca
     8641 gaataatcgt ggctgtacca gccacgcctc ccgtgcatcc ggaggtagat acaatccccc
     8701 tcaaatatcc tgttttggac aacaggggaa tcaacggaga cgagtgttac tacctcctgc
     8761 agtctcttgt agaggggggc attccccagc aggtccgggt tccggatctc gagggcaaac
     8821 cgacgcccca gaccgcatga ttctgcaaac cggaggagga tatccggatc ggaaaagcgg
     8881 ggatgtgcct ggaagaggta gaagtctacg aaggggtcaa gcgggatgaa agcctcccgg
     8941 aaccttttcc agagaacacc cgctgcctcg ttgaacctgt gcgtatgggt aacaccacgg
     9001 tggaccttga cggcccatgc aagttcccga cccttccggg accagccgag gatctggttc
     9061 ctgaatggaa accggtagaa acttgcgttc aactcgactg cattcagccc ggagttctga
     9121 atgtaccagt caaggtttcc cccctcgttc cagtcatagg accagccgct ggtcccgaca
     9181 aagacctcca tggtcaggac tcccccctaa cgagagaaaa accttgttcc acgatgcagc
     9241 agcctgaccg gttgcggcaa tcactggttc cggttccatc tcttttgtcc agtttttcct
     9301 cttctctgcc cctgtatctg ctgccggtaa tcgggcatcc gtggtttttt gggggaggtg
     9361 atgcccgggg ctccccggta tgtttcaaaa gtcctgttcc tggcatacct tcattatacc
     9421 ttcatgtgaa tacagttcat caatgaagga tattgtcgcg acaaggagaa tggaaaacgg
     9481 aattgcatgt tactatggag aaaagggaaa ggaggaattc gagaccttca attacaatga
     9541 gctgatcgac atgaaaatta acgccctcga cctcctgaac gacccgaaaa attacgcagt
     9601 tgatcctgtg aatcacaagg tcgtaatgaa aaagtaatca ctgcactttt ttccagccgg
     9661 taagacccct ccccgatact aggaaatatt accaggagac tgctgttgga agacaggcga
     9721 tttcataggt attttaccgt ctggtctgct tcatttccaa aaaagaaagg ctcgtcctgc
     9781 catgtatacg tattctgcat ttctccggaa atttgactga gagagataat cagggaagag
     9841 gaggcacgcc ttagccccgg gcacgcttca aatctcatga gaatccgaat aacatcatga
     9901 tacagcccac gtaggcaccg agcatgactg ccccccatgt ccttgttatg gcactctgct
     9961 gaaaaaccag gataaggacg gcaagcgaga aagcaaggag tatgacgagg ttccacggaa
    10021 ccgggacggg gatgataaaa aagagggaat tgagaccgag gataaagatg aggttgaaaa
    10081 tgttgctgcc caaaacgttt ccaaccgcaa gatcgatgct tcccttgagc gtggccgcaa
    10141 cagacgtcgc gagttccggc agagacgttc cgattgctac cagggaaaaa ccgatcagga
    10201 actcgggaac caaaaataaa cgtgcgatat cgactgcacc tgcaaggagc aggtgtgccc
    10261 ctgttatgac caggaaaatt cccagcaccg ttatggcaag ggaatattta aggggtctgg
    10321 gggtgcaggt gaccgcatcc ggcttttcct ccaaccgggg gagacggatg agaatcaagg
    10381 aaaaacaggt gagaaatacg attccggtga tgatatccaa tgttgcccgc agggagaaga
    10441 gaataaaaag ccctgttgca aggatcatga tcaccatgtc ccgctgaaca ttcatcttcc
    10501 ccgattcccg ggaaattgca tcaggcctga ccaatgcgca tatcccaagg atcagggcga
    10561 tatttgcgat attactcccg atgatgttcc ccatgccgac actgaagttc ccgaggctga
    10621 aagcctctgt ggtcaccacg agttccggga gcgaggtccc gaatgcgatg acagtcgtcc
    10681 cgacaaagag aggcgaaaga cccatcccca gggccacgtc ttttgcaccg tccaccgtga
    10741 tgtccgcacc tttcacgagg aggagaagac cggcgatgaa gagaaggaac ggcaggagca
    10801 tgggagccct tgagaaaagc gggggaaggg atcactcatg aacttttgga tcacggggta
    10861 atgctgcccg gcatcacccc gccactcaac cagtctcccg gagatgtcaa ataggggaaa
    10921 tatcacacca tggtacaggg agggccctct tcccggttac ttccatgtcc cgccgccgaa
    10981 aaatacccat ccgtcccggg ctctcacccg ggacacttgc agtggatggg aagcacacga
    11041 aaggtcccgt gggcatcact gtcatcgact acgatgcaac gcacttttca gagaaaaagg
    11101 tctccgccgt cgaggaatgt tatcccttca gggatacggg gacagtcacg tggattaaca
    11161 tcgacagcct cgggaacacg gaagtgatcg aaaagctcgg gaaccattac aacattcacc
    11221 ccctcatcct cgaggacatc ctcaataccg gacaacgccc gaagatcgag gatctcgatg
    11281 gttatctcta cgtaaacctg aagatgatcc ggctcgtggg ggagagaaag gagatactga
    11341 tagaacacgt cagcctcatc atgggctcca acttcctcct tacgtttcag gaagatacag
    11401 gtggagatgt tttcgatccg gtgagggaga gaatacgtaa ggaagggcga atacgcaagt
    11461 tcggacccga ttacctggcg tacgctctca tcgatgatat cgtcgatcac tacttcctcg
    11521 tcatcgaaca ccttgaggag gtcgtcgaag acctcgagga agagatcgtg cggaatgcga
    11581 cgccggctct tctccataag atcacggcac tcaagaaaaa gatgataacg ttacgaaagt
    11641 ccatatggcc cctgcgggaa gtcatcagtg gcctcgagag atcggactcg ccgctggtca
    11701 aggacagcac ccggatttac ctgcgtgatg tgtatgacca tgtcatccag gtcatagaca
    11761 cgctcgagac gatccgtgag atgttgtctg gcatgattga tatctacctc tcgagcctct
    11821 ccttccggat gaacgagatc atgaaggtcc tgaccctcat cgcaaccata ttcattccgc
    11881 tcacgtttgt cgcaggggtc tacgggatga acttccagta tatgccggaa ctgacgtggg
    11941 aatacgggta ttacaccgtc tggggagtga tgatttccat cgtcgcgatc atgctcgttt
    12001 acttcaggaa gaggcagtgg atatgaacgg gttgagaccc ggatgaaccg cggccggaaa
    12061 ccggaacgcc cgggagatgt gaagaactga tggaaatcct ccttgcaata gtactcgcgg
    12121 ttgctccagg tattttctgg ttgctctttt tttattccag ggacaggtac gaccccgaac
    12181 ctcccgtctg ggtaatgctt gtcttcctcc tcggcggggc agtcacgttt cccatcggaa
    12241 tcctcgaagg aagtctcctg gcaatatcag gaggattcct tggatcagtc ttaattgctc
    12301 ctgtcttcga agaactcgca aaatactggg tcgttgaaaa aacggtctac cggacccacg
    12361 tcttcgatga accggtcgat gggatcgttt atgccgctgc ggccgggctt gggtttgcaa
    12421 ctctcgaaaa caccctctat gtcctctcag ccctcgacga gtcattcctc tttgctctgc
    12481 agactgcagt tctccgcggt atcctctctg tcccggcgca tgttctcttc tccgtgatgt
    12541 ggggttttgc cctcggggtc tcgcaggggg gatcccgaag aagacacgat cccatcgtcc
    12601 tctgggggct ttgccttgcc gtcggggccc atgccctctt caaccttctc ctcgtgtccg
    12661 gcactggtat ccctgtcctc ttactcttcc tcgtcccgct cctctgggtg gtgacgataa
    12721 accgtgtccg ggatgcactc gccctctcac cgttctcggg gaggtggtga gcgccggggc
    12781 tggagggggg tgggaatggc aggtgtacct gcacaaagag accagtgatg atgctggcag
    12841 gaaaagccag agaaaagagg atgtggcgtc ttcagcgatc gaaacgcctc aggataacga
    12901 tttcgacggg gatctccttc cggtctctcc tgtgaaagaa gaattgccgc ttcaaaggga
    12961 gggttccctg gataacaccc tcgatctctg ccctcccctc gacgaaaccc tttagaaaag
    13021 aaaggcttcc cctgttgaag ataccatagg tcacgggggc aattaccagg gccgcgttta
    13081 cgaaaggcct gtcagcatgg ggattctggg caccgaatgg cgggttcatg acaaccgtat
    13141 ccatcggccc cacacggtcg acaagtcccg gatcattgat atcgccctgg atgaaaacgg
    13201 gggacactcc ctttctggcg gcattcaggg ctgcaactgc aattgcatcg ggatcgatct
    13261 ccacacccgt aacggaggat gcaccgagga gtgcagcacc gattgcaagg atcccggtac
    13321 cgctcccgag gtcacagaca cgtcttcccc cgatatcccc cctcatgtaa gcgtggtaga
    13381 ggagacgggc tgcaaggtca gggggcgtgg tatactgttc ccggtgggaa gaaggctttt
    13441 cgaacccttc aagtccggaa agatccctct caagctgctt tagtttcatt ttgcatcatt
    13501 gcatctcgtc gatggtatac gaggagaaat ctgtctcgcc ggtgaggatc cggaattcct
    13561 gcggggtgag aacaggggcg gggaaccgcg gctggtcatc atatgcaagg cgggggcacg
    13621 caaagttgac gtaggcagga aacccgaggt tgaggagttc gccgggatcg acctcgcgca
    13681 tcagcaggat taccgcgttt gggcatcccg atgccatctc gcgggcgagg gaaagcctgt
    13741 tctgcccggt ctttgagctg acgatgaacc caaaggcatc agcggaacgt gccttctcga
    13801 tcagggcaaa cctctttctt aagaacctgt cctcgtccac ttcacgggct gtccccgtga
    13861 gcggatccag cgcaatcacc ctcttcccgg ttgccagccg aactccgagc gggtgaaaaa
    13921 tccctgtccc gacataaaga atctcttcca cggaggggat gcgtgccgct tcgaatgcac
    13981 atccaaggat ctgtccctcg ctgcaccccc gtgaacccgg ccgtgtcact gccccgatcc
    14041 cgctgtctgc aagtaccctg accatcgcag ggaggagatg cacgtgctgg gcggtcgtta
    14101 caaggcctat tgtggatttc ctgaagtggt gcactgcccc tttgaggaca ccgggatcaa
    14161 aatcgactga aacgggctca aagatgactt tggggtcggg atccccgaga ggtgtgtggc
    14221 caaagtgtac cagggcatca acgaggcgca gagcatcgga cgcaaggtca cacgccccat
    14281 agcacgggtc agcacttaca atcacggaaa aaccctcttt tctcaaaaaa agagcgattt
    14341 cacgggcttt ccgtttcatt ccctcgggga actggagcgc tattgaccga acgttccgcc
    14401 ttcggagttc accggcaagc tcagaatatc cggtcaatca cacgcaccct gtcggttacc
    14461 tccacgctca ccagcgtctt gtaactccgt ccgatatcgg gttttcccct tttaatcaca
    14521 aaacagacat ccttcaccgt ggcgcctgcc tggtccaggg cccagagaag agccctcgtg
    14581 gtgcctcccg tgctgatgac atcatcgaca ataacgacac ggtccccttt cctgacaccg
    14641 ttgaggtaga tctggccttt cgagtatccc gtggcctggt ggacggcaac ctcgcccgga
    14701 aggcggtact ctctcttgcg gacgatgttc accggtatgt ctgtcacgag ggagagagcg
    14761 ataccgatgg gaatcgccat tgcctcggcc gctatgattc tgttcacccc gtcaagatcg
    14821 agcaccttga caagggccgt gcagacttcc cggataaggg ccgggtcgac ttccgggact
    14881 ccgtccgtaa tggggtggat gaaatagtta tactcgcccc gcttcacgat gggggcattt
    14941 tcaagggatg cgataaggcg ttcaagcatg gatatcaccg atgtctttta ggaatgattc
    15001 aatgattccg gcatgcacgt gcggcatgca cacgatgcgg aggtggcctt cccgtgtcca
    15061 tgagaccctc cagggggccg ggacattcgt ttttgcaaag gttgcgacat tcacgtcggg
    15121 tgtcacgata cgcgggatcc caaaggcttc catcccatcg ataagccgcc acgtgttctt
    15181 catgcagccg gccacgatgt ctctcatgcc ctccttcccg aggtactcga ggacggccag
    15241 ggcgccagcc accggtcccc ccggtctggt cccggataac gtgaattcct gcctgacgga
    15301 gaggtagggg gtgtcgaccg caagggaact gaaggcatcc ttttcccgga tgaggaggac
    15361 tcctgccggt atggtgctca tccccatctt gtgcgggtca actgcaatgc tgctgacccc
    15421 gggcagggaa aagtcaaatg gcggggcatc atcgaggaaa ggaagaacca ttcctccgaa
    15481 tgcggcatcg acatggagga agatgccgaa atcggctgca atagaggaga gttcccggat
    15541 tggatcaacg actccgtatt ccgttgtgcc ggcaaccccc acgagggcgc acgtgttgcg
    15601 gtcgatgagt tccgggaccc tttcagcatc catcctgaat tcacggtcga gtggcacggt
    15661 tcgcatctcc aggtcgagga tgtcgcatgc tttctggaaa gagaaatgaa ctgatcgcgg
    15721 gaccaccacg ttgggcgtcc ttgatcccga gagtctcttt gctatcctga gtgcctggat
    15781 gttcgattcg gtcccgccgg acgttgcata gccgtaggcc gcaggcaggg ataagagcgt
    15841 gcccagacgc tcgatgagga gcgattcaag cgacgcagtc ccgggaaaaa gaccggggtc
    15901 tccgagattt gtctcgagga aaagggaatg ggcccgggaa gcaaccgggt ggggtatggt
    15961 gcacatggag ctcagaatat actcgtggct cacatcttcc tgtctctttg cggaaaggaa
    16021 ggaaaaaagg tcgtcgatgg atcggccctt ttcacgcatt ccgggatctc gcgttctcca
    16081 ggatgatctg ctgctctgtc ctcgcaacgg tctcacggat ctttgcgatg gcatcgatat
    16141 ttgcagagac actcgttata ccgtgctcga cgagccacct gaccatcgga ggttccgatc
    16201 ccgcctgccc gcatatggag atctccacgc catgtttccg gcagcacctg atcgcggaat
    16261 cgatcagggc caggaccgca gggtgttttg gctcgtacat gctggcaacg ttctggttgt
    16321 tccggtcgat ggcaagagta tactggacaa ggtcgttcgt gccgaaggat gcaaaacgaa
    16381 tccctgccct gatgaaatcc tcgatcagga tggcgctgct cgggatctct atcatgacac
    16441 cgagcgtcac cttatccacg tcaacccccc atttcctcat catctcgcgg gcccggataa
    16501 actctgacgg gtgggatacc atggggaaca tgatcccgag gttatcgtaa ccctgctccc
    16561 agagtctcct gaatgcctcg acctggagcc tgaactggtc aggggactgg aggtccctgc
    16621 ggataccgcg ccacccgagc atggggttat gctcgacggg ttcgtcctct cccccggcca
    16681 tgttcctgaa ctcatcggta ggtgcgtcca gagtcctgac ccacacgggc ttgccgtaaa
    16741 aagcatcgag gacggtcttg ataccgttgt agagttcctg gatgaactct tcctcgcgtc
    16801 cgtttgcaat gaaccatccc ggtgttttat tcagaccgag gatcaggtgt tcgatccgga
    16861 gcagaccgac accatcggca cccgttgcgg cggcacgttc tgcagcctcg ggcatcgaga
    16921 cgttgacctt gacgctcgtt gcagtgatga tcggtgcgaa cccggcggac acgaccttct
    16981 ccggcttctc cctgggaata tcgacttcgc cttcgtatat gaaccctttc tcgccatcga
    17041 ctgttaccag ctggccgggc ttgaggacct gcgttgccgt tttggtcccg accactgccg
    17101 gggtcccgag ttccctgctc acgattgctg catggcacgt catgcctcct tcgtccgtga
    17161 cgatagcggc aacccggcgc attgccggta ccatatcggg attcgtcatc cttgtgacaa
    17221 ggatgtcacc ttccttcact ttccccgcat ccctggcgtc gtgaatgatg accaccctgc
    17281 cgcttgcaat tcccggcgag gcaccctgcc ccttgagaat gattgtctgg gtgcccgccc
    17341 tgcctgcgcc tgattcctcc ctttttcccg tccgaatcgt tgtgatgggg cgtgactgga
    17401 ggatatagat ggtattcccg acaatggccc attcaacgtc ctggggaaca ccgtagtggt
    17461 tctcggctat ctttccatat tttgcaagtt ttgcaacctc ttcatcggag aggagggggg
    17521 cgtcctggag ttcctttggg acttccaccg tcttggtacc atgatccccg tcagagacta
    17581 tctggaaccg cttgtttgaa atgagacggt cgaccacttt tcctgtccgc atatcaaaaa
    17641 cgtatttgtc cggggagaca gaccctgata ccaccgattc tccaagaccc catgaaccct
    17701 cgatgatgga gacatcttcg ccggtcacgg ggtgggatgt gaacatgacc cctgcctttt
    17761 cggatctgac cagttcctgg accacaacgg cgatgttgac actcctgtgg tcgaatccct
    17821 gctttgccct gtagtagatg gcccgggctc catagaggga tgcccagcac cgctggactg
    17881 catcgatgag gtttttctct ccgctgatat tgaggtaggt ctcctgctgg cctgcgaaac
    17941 ttgcatcagg aaggtcttcg gctgtcgcac tggaccggac tgccacaacc atcctgccgt
    18001 tatccatctt cctgtatgca tcacgtatct tctgcttaat ggatgccggc atctttgctt
    18061 tcaggacggc ctgttttgct ttctcagccg cgttctcaag ctcggcgctg ttctcgacat
    18121 ccagtctctc gagctcggaa aacagggttt tttcaaggcc ggtctcgacc aggaactggc
    18181 ggaacgcatg gctcgtgacg acaaaggccc gtgggacagg aagcccgatt gccgacattt
    18241 caccaagtga cgctcccttg ccccctactg cagcaatatc ttctttccgg atctcctcga
    18301 gccagagaat atcaggcatc tctctcattc gcgcaccact attattctgc gtcactcccc
    18361 gtttaataca ttctcattcc acggcccgga agattccagg atggcagagt ggtcacaagg
    18421 aaaggacaat gtcggtccct ccaggtcccc tgtcgataat aatcctcaat atgtatcagg
    18481 cctatagtat ctgggaattt atggcggatt ttaaaatact ggtcagcgat ccccttgcag
    18541 atgaaggcct ggaaattctg cgccgggagt gttcggtcga tgtgaagacc gaccttaccg
    18601 aggatcagct cgtgcagatc ataggggatt acgatgcttt gctcgtgcgg agcgggacag
    18661 atgtaaccgc aagggttatc gaagcaggaa agaggctccg gttcatcgga cgtgcaggtg
    18721 ccggtgttga caatattgac atggaagctg ccacgaagaa aggcatcatc gtggcaaacg
    18781 ccccggaggg aaacaccctc gcagccaccg agcataccat ggcaatgatg ctctcccttg
    18841 cccggaacat cccccaggca aatgcatccc tgaagaaaaa ggagtggaag agatcaaagt
    18901 tcatgggggt cgaactgaat gagaagacac tcggtatcgt gggactcggc aggatagggc
    18961 gcgaggttgc caagagggcc caggccatgg gtatgcatat cgtcgggtac gatccgttca
    19021 tcacgcggga ccgggcagcc cagatgggtg tcgaggctgt ttcgctcgag gaacttttca
    19081 aagctgctga cattatcacg gtgcataccc ccctcatcaa ggagacccgc cacatggtga
    19141 acgagaagac aatcgccatg atgaaggatg gcgtcaggat catcaactgt gcccgtggag
    19201 ggatcatcga cgaaaaagcc ctttataacg gactgaaatc cggcaaggtt gccggcgcag
    19261 ccctcgacgt tttcgaggag gaaccccccc tgaactcccc cctccttgaa ctcgaccagg
    19321 tgattgtgac acctcacctt ggagcgagca caatcgaggc ccagaagaac gttgctgtat
    19381 cgattgcaaa gcaatgtatc tcggtcctga aggggggttc tgcaaaatat gtcgtcaatg
    19441 ctcccatgat cccgcctgaa cacgcggata cgatcgagcc ctttgccagt cttgccgaaa
    19501 agatggggcg tttcctgacg cagcttgtgt cagggaggat ggagaaggtc gagataatct
    19561 atggtggcga gcttgcgacc ctcgggaaca acacgcggtt catcacgctg atggcactca
    19621 aggggctcct cgatcccatc ctccaggtcc ctgtcaatat cgtcaatgcg gagctgattg
    19681 caaaggagag gggaatttcc gttgccgaga ccatgacccg tgactccggc ggtttcaaga
    19741 gtcttgtcac catcagggtg aagaccgata cgatggaaga gacgatgagt ggaactgttt
    19801 tcatgaaagg acggtcgcgc atcgtttcga tcggtggcta cacgatggac atgattccgg
    19861 agggctacgt catcgtttcc aggcacctcg acaaacccgg tgttataggc cgcgcttcca
    19921 cgatacttgg gaaagggaac gtgaatattg cagggatgca ggtcgggaga atcaggccgg
    19981 gcgaagaagc tatcatggtt ctcaacgttg attccgaggt cactcccgag atgatggaag
    20041 agattcgctc gatgcccgga atattcacgg cagtctttgc aaaaatatcg gatactttaa
    20101 tctgaagtgg ttttgctctg tcgctgaccg gatagggggt tttatccctc ttttttttcc
    20161 gctgtcattt tcatatcagc gctgattgtt tcgatccggt gtgtgaaggc caggcgatac
    20221 cagaaaagag aacaatttta tactgtgttc acccacattt ctccgcacaa attgaccaat
    20281 cctgcgggct cgtggtctag ctggttatga cgtcgccttg acatggcgga ggtcaggagt
    20341 tcgaatctcc tcgagcccat ttccttttgt tttctccatt tgtttttgga aaaatggatc
    20401 aatcgatcca tgcctttcac gtttcgaaac ccgaatccaa actgcatggt tttttatccc
    20461 ctgcctgacc aatttcataa aaggggggtc ctgccgagtg ctctctcttc tctatgtgga
    20521 tgacaagccc gagttcctgg atctcgtgaa acttttcatg gcaaagaggg gccggttttc
    20581 catcagtacc tgccagtctg catctgaagc catcaaagac ctttccatga accggtacga
    20641 tgtgataatc tccgattact acatgccggg aatggatggc cttgcatttc tccgcacaat
    20701 caggggaatg ggagatcaaa ctcctttcat catgtgcacg ggttttgggg gtgattcaga
    20761 ggagaaagag gccctcggtg caggtgccga tttctacatc gtgaagggcg gggactcggg
    20821 aattttcttt gatctcctct gcagggctgt ttccaccgtt atcaggaata aaggtgagag
    20881 gattggtccg gatagtgccc ggggaccaca gtgatatcca ggtcatgacc catgtacgat
    20941 gaatctgccc tccggaggtg gatgggactt gaaatgcgga agattaacga aggggtagcg
    21001 gacacacgtg tctccctcca tgcccttctc atgatggaaa aaccggtgac cgtcacgaag
    21061 ggcgggcagg agtaccggtt cgataaaaga gtcctggaag acattgcatc gaggctcccg
    21121 gttgtcctcc aaaagaagct ccggctcccc gtcatattct actacgacat ggaggttccc
    21181 accagttgtt tcctttcgga cagggttgcc tttgaagccc tccaggagat gggggaattg
    21241 tcccgtgaaa gggtgtggga aggggggagg gtctttgttg gaagggcaat tgtctttgca
    21301 ctcatgcgtt cgtacccgac ggttttccag ataatgatgc gatgaagaag gcggggcatc
    21361 agcatgggac atctccactg gttttttata gaaaaatgca gatgactatc gctatgggtg
    21421 agacttgtcc gggggattga gtgcatgaac ggtggcatcc ttatcgttga agacgacccg
    21481 gtcatcagcc agctgatcgg gtggagactg gaaaagatgg gttttttcgt gagtggaaaa
    21541 accccgacag cagaggaagc ccttgataag ataaaggacg ggagaccgga cctgatcctc
    21601 atcgatatca accttcccgg cacgatggac ggtaccgaac ttgcccggac aatcaaggaa
    21661 cagttccaga tccccttcat attcctcact gcatacaccg acagcgagac catttcccgg
    21721 gccatcgaca cagaacctgc cggttacctc ataaaacctt tcaaggacga ggaactgaag
    21781 gtaatgattg aacttgcact ccggcacgca aagaaagggt aatatcacag ttggtttttg
    21841 gggagactgg aggaagaaga acacgattgc agagcagggt gggaaaaaag gggaatactg
    21901 catgggtttc attcttaaat cggcctgctt ttttcttttc ctggcactcg tcctgcagcc
    21961 tgccatcagt gccgcggatg actgtggatg cggcggtggt ggcaccacgg gagacagcag
    22021 cgatatctcg tccgggggtt acggatcctc agaagatccc atgattcacc tcgtcagggc
    22081 acgcgaattc ctgtcccggg gtgatcttcc gatggcgatg gccgagtgca gggaatcact
    22141 cacactggat ccccataatg ttcaggctct cctcctcgag ggagagatcc tcttccggat
    22201 gggaaggtac ggggaggcag cggaggcgtt ccggaaggtg accgggatgt acccttcgga
    22261 ggaggaagca tacacacggc ttgggaacac ctacctgctc ctcggagatt atcgttctgc
    22321 agagaaggca tacacacggt ctcttgcaat ccgccccaat gatcctgtcg tccgggagaa
    22381 cctggagaaa gccgtgaggc tgtccgggca ggagaacccg tctcccggga aggagatctt
    22441 tgagaatggt accgtgacag gaacggcccc gcgcacccgg gcggaatccc ccgagcctgc
    22501 ggaactgacc actccccgcg aagaaaaagc tgttcccctg tcttctcgta cgcctaccac
    22561 cgatctttca cccgttccct tcctgattgc gcttgttgtt accgccttca taacccggag
    22621 cgaaaaaaag ggatcaaaga ctattctctc cctgaaggga ttgggatgaa ggaaggcacg
    22681 accaacatcc tcatcaccgg gcctcccggc tgcgggaaaa caacccttat caaaaatatc
    22741 atttcggacc tctcttttct ctctcctgtg gggttttata cggaagagat tcgcgaaggg
    22801 aaaatgaggg tagggttccg gggtgtttcc ctcgatggac gcacattcct gcttgcccgt
    22861 tccgggtttt cgtcccgttt ccgggtgggt aagtacgggg tcgacaaagc ggggtttgaa
    22921 tcattcctcg cgacgatccc gtttcaggac gccggatttg tcgttattga cgagataggg
    22981 aaaatggagt gcatatccgg gcagttctgc catctcgtgg aagatttact ctcctcggaa
    23041 aaatgccttc ttgcaacaat tgcttcaagg ggtaccccgt ttatcgaggc aatcaggcaa
    23101 cgggacgacg tggagatcca tctcatcgac aggaaaaacc acatggatat tgcaggaagg
    23161 gtaaaagaac gcatccgtgc cctgatcgaa aggacctgat ccattcattt tcccggttaa
    23221 ggggaggatc gtgtcccgcc acatccccgg tcaggcggca tggcgacagg gtaacccata
    23281 tgtgtcaaca gatcataaaa acaggtaatc tctatggaat ccatgaaatc cgttatcctg
    23341 gcagggggag tcgggaccag gctctggccc ctctcgagga catataatcc caagcagttc
    23401 ctcaagatga acgggacatc tctcttccag gagacataca aaagggccat gcgtttatcg
    23461 aaacctgaag acatctatgt tgtcacccac agggaccacc actatctggc tttgaatcag
    23521 atcgaggaat tgaaccagaa cgttccggat gggcgtatcc tgtccgagcc tgtggggaag
    23581 aatacactcc cggcaatcac ctgggcgata ctcgagatag aaaaggagtc tggtgaatca
    23641 ctcgttgccg tgttccccag tgaccattac ctcggtgagg atgcaatgga tgagatcgct
    23701 gcggcaggca ggattgccgg ggacttcctt gttacgttcg ggattccgcc cactcacccc
    23761 cacacgggat atggatatat tgcaccggga gaccccctct ccctcgggtt cagggtgagc
    23821 aggttccggg agaaaccgga ctgggagact gcaagggtct ttgtggatgc cggttatctc
    23881 tggaacagcg gtatgttcct cttctcgaca aatacttttc tcggggagct tgagcggctg
    23941 cagcccggga tatacgtccc catgagggaa aaaggcgttg cctcataccc cgaattgccc
    24001 tctctctcgg ttgattatgg gctcctcgag gtttccgacc gcgttgcagt cgtgccactc
    24061 cgggccagat ggacggacct cgggacgttc cgcgcatggt acgatttcaa gcagcacgac
    24121 agccatggca atgcgggaga ggcggaattt atcgattctg agggtaattt tgtgcatgcc
    24181 cccgggaaaa aggttgcact ggtcggcgtt aaggatctcg tcctcgtcga cacgggcgat
    24241 gccctccttg cctgccggat ggatatgaca gagagcgtcg gaaacctcgt aaaggttctt
    24301 aagaaccgcg gtgatacaat cacggactat cacctccagg tacaccgtcc ctggggttct
    24361 tacaccgaac tcgagagatc gcggttctac cggatcaaga gggttacagt caagccggga
    24421 aagaaactct ccctccagat gcatcaccac cggagcgagc actggatcgt tgtcagtggc
    24481 atggctgatg tcatcctcgg ggatcgcacg attcacctga gacagggcga gagtacattt
    24541 gtcccggcag gaatcaggca ccggctggcg aacacgggaa aaatccccct tgaagttatc
    24601 gaagtccaga tcggcgagta cctcgaggaa gatgatatca cgcgatttgc cgatgattac
    24661 aacaggatat gatggaaata ccgggcacgg actcactcat cacctgcctc tgtcacggga
    24721 tgagtagcag gattccctgt gatcacgggg cagcggcgta ttgcaccggg tgatgccggg
    24781 aatgccgggc tgatcgcccg ggaggtcagg gcttacagat gtctccactc gcaaaggata
    24841 cggtcatggt cgtccatggt gcggagatat ttgatacggg aaatgccgcg tggctctttt
    24901 cggtccttgc accgtgcagg attgtcgttg ccggcatcat ggcccgtgtg gctgcggaag
    24961 agttcgggct tccctgcgaa tttgcagaca ttcccccgag catggtgatg aggaggctcc
    25021 accagccctg tttccttgcg aaccggggaa agagccctga atcgggccgc attttcggtg
    25081 agatcgtggc ccggcgggtc ggggatgagg gaatcatcca cgtcgaatgt gcatcggggg
    25141 aggtcatatg ctggaacagg tacccggatg acctcgcgag ggagatagcc acgctgacag
    25201 gctattccct ggtcagcgga gtcaccatgc cggaagggac ggagccggga acccgggtca
    25261 tccggggatg cctcccgggg gaggccgtct ttgtaaacgg gactgtcatt ggcgtggcaa
    25321 caggccgcga ggtcgtaatc agggtaagtg aaaaaggagt ggaacccgtc cttggtcttt
    25381 cagtaaaagt acacggcctc gaaaaactca ataaatcggg cccgatcgac cctgccacgg
    25441 cctggtgcaa gagcggcccc atccgtgcac gggaaccagt gacgacgaat aatgcaccac
    25501 caaagaaggg ccgggtcgta ttcattgacc actgtggaca taccctctat cgcagcgtct
    25561 cgtccgatgg tgtctgcggg attgtcagcg tgggtgatga cacaaccgcc gtctgcgccc
    25621 atatcggtgc gcacctcggc gtcccggttt tcgggatcgt ggatggtgac accgacggga
    25681 ttgttcctgt ccgctatgcg ccggggtccg tcatcgcagt ggcaaccggt atttcggatg
    25741 acgatctcgg aaaagaggtc gcagtgatga ttcctgcaga agaggtggac tgggacgatt
    25801 tcatccgtat gctggtggct cgtatcgggg acagggcaag gatatgcagg cctccccatt
    25861 catgagagcc tgatttattc tccaccgggc tttccctgga cagattgtct ttggaatcgc
    25921 tctctgatgc tatccagggt ctcgatatcg gaaatcccct tgtcgtccct gaccctgata
    25981 aaccggggaa acctcagggc aaacccgctc tcgtagttcg ggctcttctg tatctccgag
    26041 taacccacct cgaagacgag gaatggttcc agatgaacct cctttccgga ctctgaaatc
    26101 acgcggtcct tcagcaactc gtaaacctcc tggagttctt catccgtaaa acccgttgcc
    26161 acctttccaa cggggagtag ttcacccctg tcctggcagg caagcaggaa tgagccaaag
    26221 agatgcgccc tctttccctc cccccattcg gcaccgatca ctgcaaggtc aatagaatcc
    26281 acgcctggtt ttattttgag ccagttcttt cccctgatac ccggtgtata ggacgaggaa
    26341 aggactttca gcatcagccc ctcgtgacct gcatccaggc tctcccggta aactgcctcg
    26401 atgacagaaa tatcggaact taccgtctgg ggagcgacgc aacctgacat tgcttcttcg
    26461 aggtatttcc tcctctcccg gaaggggtcg tcgattaggg tctttccatc gaggtagagg
    26521 atatcgaaga caaagggctg catcctgatc tccttctgca ttgccgcgat atcgtacttt
    26581 ctccggaacc ggcgcagtac agtctggaac gggagaggcc tgccatcctt aatggcaatc
    26641 acttcgccgt cgaggatgac atcgtgggaa gtagcgttct tcagggtctc cacgacttcc
    26701 ggaagggcct ctgtcacgtc ttcgagtttc cgtgaataca tcctgcaccg gttgccctgc
    26761 ttgtggaact ggaacctgct gccgtcgtac ttgtactcgg ccgccatcgc gccgttttcc
    26821 gcaatggcct gactgatgga accctgctgg gcgagcatca tcttcacggg gtgaaaaagc
    26881 ctgatgtgga catctgcaag ggaatccctg ccttttcttg cacgcaatgc cacctctcca
    26941 aggtcattta tcgcctggta ggcatgctcg accagggacg ggtcgacgga aaaggcctgg
    27001 gcaattgcat cccgcatggt accctcgcca acccctatcc ggaggtcttc caggataagg
    27061 cgggcgaggt actttgcctc gaggggagac gcattctgga agaggttctg gacgagagag
    27121 agtttctcca cctgcgaaga acgtccctcg agacgtgaga tcctctccag gtccgaatag
    27181 acggaggaca ggtcgagttc ctgcgagaag agggatgtct ggaacgttgg ggagcgtccc
    27241 gatcgtttcc cggctctttt attttccagt attgcctgga cagcaagtcc cacgtcgccc
    27301 ttcctgttga tctcgccgat aatgtctgac cgcgtggcat caacaacctg ggtcagagca
    27361 tcaaagagga ggtttggacc gatacctatc ttattgggac tccagtcggg gaagatcctg
    27421 ccggtcagga accggacgaa gatggggaga tccccctcgt caaggctggg gaggatagcc
    27481 gagatctttc ctgtcatctc gagccgccct ccgatgccct ccagctgttc gcagatccgg
    27541 gcaaattcaa ggaatttcat gatgcctctt tccatttaaa cctcagcacg ggcagaaaat
    27601 aagggttctc ttcgcatgta ggtcgtgata aagacctgca tcaccttttt ttgttctcct
    27661 tttccgggtc tcaaggttct tatagtctca caggaaattt ctgtatgtaa tggcgggaga
    27721 gtgggtcccc gatgccctta tcgagcagaa gatggggcag accaagcggg agatgatgga
    27781 ttacatcgag aagaactcgg agaagataga ttcgaatctg cccgtgttct ttggccatgt
    27841 catctctatc ctggagaaca acttccctga catccctgac caggtctacg accggttcat
    27901 tgatgacgtc acagtcaagg tgctcgagga gagcaagcgt tccaccgatg ttgaatacat
    27961 cgaaaggctg ttccgccacg caacacgggt caagaggaaa tataccggca gggcgatctt
    28021 tgatatcgtc ctgggtctca agctcatcga tatcggaaaa tacaaggatg ccatcgacat
    28081 cctgatgaag taccggaccg ttgacgctat cgtctgcacg gcaattgcat tctgttacta
    28141 cgagctgtcc gccctcgaac tgccccctga ccagagaccg gacaagagca ccacgagcag
    28201 catggctctt tccgcccggg agcagatgat cgagcttgca cggcttcagc caccggtcaa
    28261 caggctgcgg ttcccccagg ttatccagga actgcgtgtg aacaagatct tctggttcat
    28321 gataaaactt gcaatagact ggttcccgga ccagcctgtt tatctcaaga tagggctcga
    28381 aaaggcaaaa aaggaccaga acagggatat gaggggagaa ctcctcaaga tagcggcaga
    28441 gcggtattac agcgacatgt tcttcctgcg cgacctctac cacttcaagc tggaagcaag
    28501 ggatgcaggg ggagcgactg ccgtggtgag gcagatgatg cagcagcacc cggacgaact
    28561 cgaacccctc tactacgggt tgcagcttgc gatcatgtcc tcgcaggatt ctgcctacca
    28621 gaagttccgg agcactgcca tctcgaaaaa gatgcccgca cacgtcatcc tcctgctcga
    28681 ccttgcattc ttcctcatca gcgggaggag aacggatgca gaagtgatgt tcgaggacat
    28741 ggagaaaaaa ctccctgccc ttggttatta cctcgaggtt ctcgactacc tcatgcagga
    28801 catattctcc gaggacgaaa aacggtcaaa gacggcaaga aaggtgttca tggactcgat
    28861 cgaccagtac tgcctgaaac tcataaagat gaaggaagac tgatttcctt ttggaaaaag
    28921 aatcactcag ggatgttaag gcattattcc cgatactgtg gcgatcaggg gccgataccg
    28981 tgagatccgc attccgcgac ctgccctttg cgtgcccgtg tcgactgtca gggtaagaaa
    29041 gatgtttttt gtccatgaat aatgcatgag agacggttga aaaaccatta tgccggcgcg
    29101 gattctccct cctgcatcag aggaaaatac catggggcca tcccgcatct gacccggcgt
    29161 ttgtggcaac cctgatctca agatctgaat agaagagtcc tgcagcctcc ctggcgcatg
    29221 cgagtgcctt ttccggggta ttgttcacct cgctcaaatg cgcgagcagg acggaatgca
    29281 cctgcgtgca gagccccttg atgcactcag cggcggcatt gttcgagaga tgaccccggc
    29341 gtgaccttat ccgccgcttg agggactcgg gatagggccc ttctttgagc atatggggac
    29401 aatggttact ctcgaggacg agaccgtcgc agcgggagag gtgctcgatc atgtggtcgg
    29461 tgaccatgcc ggtatcagtg cagcacccga gagtttggtc gccattccgg atggtatacc
    29521 cgcatggttc ccttgcgtcg tgggatacag caaatgccct gacagaaaat tcacccacgc
    29581 agaaatcctc gccgtaatca attctgactg ccctgacggg ctttcggtgc acgcctcccg
    29641 aatcgaggag atcgacgagg gtcccgccgg tcgcatacac cgggatggaa aggtggcgtg
    29701 caaggggcat tacggctgcg atatggtcga tgtgttcatg agtgacgagt atggcagcga
    29761 ggctgtcggt ggtctttcct gcagcatgga gccgtgagag tatttcccgg cgggtaagac
    29821 cggcatcgac gaggagggag gaagactctc cttcgataaa caggcagttt cccttactcc
    29881 cgctcgcaag agagatgcac cgcattgcat gaatattgtg catgaaactt aaaatgcatg
    29941 gtgatgcggg cctgggcagg ttgcaagaca acgggaccgg acaaaatttg ctgtttcaac
    30001 ctgccttttc gaccggcacc acgtggacgg catttgcctt gaatgaaacg gagacggtca
    30061 tgcccgggga aaggccgagt tcctggcagg attgccgggt gatgaccccg gtgaggcgca
    30121 ctcccgcatc cacggtgacc ctggtgttgg gaccctgggg gatgaggcgg aggatggttg
    30181 cagggagcac gtttcgcggg ctgctgcggc ctgcagttgc atctttcccg atgaagaggt
    30241 cttcggggcg cacaaagaga gtgactcggg tcccgggatc gaggggagag ggggcgtgca
    30301 ggatcactcc ggagacgtcg atggatgcaa gacctccctc gttggcaacg atttcacctg
    30361 caaggatatt gtcgattccc accatgcggg caacttcccg ggtaacgggc tggtaaaaaa
    30421 tctggaaggg atttccgagc tggcagatct tccggtcgag aaccaccgcg atccgggtgg
    30481 aaagcctctg tgcctgggcc atatcatggg tcgagaggac gatggtaatt ccgctctttt
    30541 cgttcaacga aaggatgaga tcctcgatct tttcggttgc gaccggatca aggtttgcag
    30601 tcggttcatc gaggaggagg agccggggcc ctggtgcaag tgcccgtgcg attgcaacgc
    30661 gctggagttc gcccccggag agagtattcg ttctcctccc ttcgtaaccg gaaaggccca
    30721 cgaggtcgag gacttccgaa accctccggg agatatcttc aggggcgaac ttcctgaact
    30781 tcaggccgag ggcaacgtta tcagccacgc tgccccggag ggcagcaggt ttctggaaga
    30841 ccatgcccat ctgccgccgg agtgccacgc gcagggcatc cggagtacgt gtgtccttgc
    30901 ccatgaccat caccgtcccc gaactgggat tgtcaagcat ggcaataatc cggagaatgg
    30961 tcgtctttcc cgttccgctc gggcccacca gggaaaaaac ctcgcccttc ctgacctcga
    31021 aggagagatt ggacaggacc tccttttcac cgtatctctt gcaaacatgg tcaaaccgga
    31081 tcatgctacc gctcctggac gatgaaaagt gcgacagtca cgaccattgc aattccaagg
    31141 aggatcatcc ccagagcaat cgataatgca atgtttccca tcgacgtttc cagggcaatt
    31201 gcagtggtga ggacgcgggt gtagccacgg atgttccctc cgatgatcat ggcggcaccc
    31261 acttccgaga tggccctccc gaaaccgagg atgatgccgc cgatgattgc aaacctggct
    31321 tccctgatga tggtcaggat tgcctgcgtc tgggtggctc ccagcgccac tatctcgtcg
    31381 gatatggccc ttttcacacc tgagagtgca acaagtgtca tgccaaccag cacgggtacg
    31441 atgaggactg cctggccgat caccattccc accggggtga agaggagccc gagaaagccc
    31501 agcggccccg tgcgggagag cagcaggaag acaaaaaggc ctgccaccac cgtggggaga
    31561 gcatagagag tctgtatgat cgtgatgaga ccgcgttttc ccccgaattc cctgaaatgg
    31621 atcaggcctc cgagggggat tgcaacaagg gatgcaacag cggtggcggc aagggagatg
    31681 aggagggatc gggccgtaat ctcgagtact tcggggtcaa ggctgatgat cagggagaat
    31741 gcctggacaa agccgtcgat gatctcgttc atgcccctcg cccgcaccga ttcctatttg
    31801 aaagaggtta aagggccggt ttcggaagcg ggcgttgtgc agtcgcactc aaaacgcatg
    31861 catcctccgt tcattgggat aaagaggccc tttccgtact tttctttccc atattcgcct
    31921 atctttgcct gtatcccggg tgatatgagg aagttgacaa aattgtttgc cattgttatc
    31981 ttttcaacgg gctggttttt tgcatgcacc gtgataacac tgtagacatt gagcaggata
    32041 tccccttctt cgatgacggg gacgaggttg agttttcccc tgtaggcgag gtacgttccc
    32101 tcgtctgtca gggtgtatgc acctttctcg gaggcaagct ggagtgtctc tcccatacct
    32161 ttccctgcct cgatgtacca tgcccctgat ctctggactt ctgacgtata attgtatccg
    32221 gatgccttcc agatgttttt ctctgccgaa tgcgtcccgg agttgtcccc gcgcgaaaca
    32281 aagaaaactc cggggttccc ggcttttcct ttacccagga tcgtcctgaa cgcctcttgc
    32341 ggagccattc cccgtattcc tgccgggtca tctgccgggc ccacaacgat gaagtaattg
    32401 taggcaaaac aacggcggtt tatcccgtgt ccaccgtcca tgaaggcttt ttcctgatca
    32461 ggggaatgaa ctgcgaggat atcacagtcg cccctctttg cgatttccag ggcctttccc
    32521 gttccctggg atgtgatcag gaggtcgaca ccgtattttt cctcgaacag cggttccagg
    32581 tagtcgagga ggccggtatc atagagactt gtggtggtag cgaggataag tttctgcccg
    32641 ttatgaggag ggaaagaagg actctgtgtt gtcgggggta tctgtgctcc atcctgaccc
    32701 gggttcgttg tcgtgcatcc tgaaatcaga attgcaccga gaacaagagc gacgagaaaa
    32761 atgaccgtgc caccatgcag ggtagagaga aaatgcatgt tcatggcttt aagtgagatg
    32821 atggagaaaa taagtattgc tattttacaa tgataaatat caacaagatt ctattaacaa
    32881 tccatgtgtt caacaggttc accggataga acctttaaaa accacagggt cgaagtgttc
    32941 tgccatgtta agggaaaaag ccctggagga gtggatcgcg aaccgt
//
LOCUS       DAOOJU010000020        30498 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1608_length_30498_cov_15.298657, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000020 DAOOJU010000000
VERSION     DAOOJU010000020.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 30498)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30498)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30498
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1608_length_30498_cov_15.298657"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            188..442
                     /locus_tag="PK679_06215"
     CDS             188..442
                     /locus_tag="PK679_06215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55584.1"
                     /translation="MPCVRREKKKSRSSGWKITHPYLFLLRSLHTASAMSTIAPAITM
                     RAKRCPQEGDYKWAIIKAHSTLFHAAMSPVMSAGYIGKEP"
     gene            529..720
                     /locus_tag="PK679_06220"
     CDS             529..720
                     /locus_tag="PK679_06220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55585.1"
                     /translation="MNSIETDVREIKENIRALTEKIEALLYEREALAMMKLSGRSLSA
                     FLDEEPDLYTVTDIKVVYR"
     gene            717..1046
                     /locus_tag="PK679_06225"
     CDS             717..1046
                     /locus_tag="PK679_06225"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF014505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - endoribonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HPC55586.1"
                     /translation="MKGKIVLIPFPFTDLTATKLRPALVLHEGEHDVVVAFISSKTPA
                     KTVESGIQITSTLPGFSKTGLKVDSVIRLDKVATILKDLIVGEIGELDDDLRADVNAK
                     IATLFRL"
     gene            complement(1524..2870)
                     /locus_tag="PK679_06230"
     CDS             complement(1524..2870)
                     /locus_tag="PK679_06230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55587.1"
                     /translation="MVHRSAGKGSSRSPAAISVLMGLFLILALLCPPLSALGFIYLDT
                     GAQPDLVAHAEGVTEYYPGDAFAMTVVLTNKGRDTAVQIAPRLSPGAYDPSTAIGVTV
                     WPQAGDAPVTIKSLPVMAGDIGSWGKARLTVSGTVFQNATPGFHTIPLVVKYRYVYAI
                     PMVGDQFSTIDLLYRDKEQVLPVTFRVRGDVRPAIRNVSCENMVPGSQGYLTALVENT
                     GYATGNSVTLRVVPADNTTFRMVDDSVFIGKFAPGDVVPLRVRIAVREHTAAGSYPAV
                     LIGEYKDDAGMIRATREVPLGIEVLRGAVFEVVNQDVVITPGRDRAITVGFRNTGDTP
                     AYDARARIIGSHVLVPSVDSVDLGTIGPGETVTALFVISADAAIPGKRYVIDSEIKYR
                     DELGALMLSDPMSFGIGIREPEGLDAITSNPVALIVIAGAIVLIADAVWRLRRRKR"
     gene            complement(2879..4033)
                     /locus_tag="PK679_06235"
     CDS             complement(2879..4033)
                     /locus_tag="PK679_06235"
                     /inference="COORDINATES: protein motif:HMM:NF019325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CARDB domain-containing protein"
                     /protein_id="HPC55588.1"
                     /translation="MIPGTTADLPLVIENKGILTMQFYNAYTLEPQYLPTTAKFARVR
                     LVPGDAPVRVKSDSQNVGDIPSGVVIPVHFVVEVPEDAKAGNYTMQAVISYSYVPQVE
                     QSGTDTLEYSFRNVEVSLPVPIVIRKVVVLSVEDVSVSDLHAGGEGYITFVIRNTGQD
                     TGDRTSIYLVPEGASPIVPFSNGVYVGTLPPGGTVQPRFKVSVSRDADPAQPAPVMLY
                     AVYRDFEGNMVRSPMSSAGVSFSEKVRFEVTSPPPVIHAGETNTMSVTYRNAGNSTVY
                     SAQARISVIDPFTSEDDTAYLGDLKPGESATATFAIKTGADATIKTYSLDSDVRYLDS
                     SQTSFTSDNIPVVVEVREGGSVLPIAIVLIIVVAGGGAYLWYRKKSAAAK"
     gene            4344..6557
                     /locus_tag="PK679_06240"
     CDS             4344..6557
                     /locus_tag="PK679_06240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrophobe/amphiphile efflux-3 (HAE3) family
                     transporter"
                     /protein_id="HPC55589.1"
                     /translation="MKTEDVFGGIAVFVNRHPKEIFVVMLVLAAISLFFAGHIPTQAL
                     SDEYMDKQSPAGIIYDLYNNRYGQDTYILLIKTPDPGDPVLLNQLLVLEKQLSRISHV
                     DSVHSVADIVAQYHGGAIPGTSAEVWAIIDRLPPDIQKKFVPDRQTALGYVLIEQGVS
                     TDASQNIEPFVVNTVGQATLPPGVSIEITGNTPYTLQFEGAMMADFGVLIIACIIFML
                     IVMYILYSKIRFWILPIVLLIFGLFYTFGIMGAFGIPANDGAIAAFPILLGLGIDYAV
                     QFHMRFDDERRQKEISPALAETLKHTGPSVLIALASTSLGFAAMFITPIPMIQTFATV
                     SIIGISCCYLTSVLGFGAIVHLVSYEPKPPGRGFTYRLNAAYERVLSTVVSVVVKIAG
                     PVVLVAVVIAAAGIALDSGIPVDASQKSMVPPDLPAQLVADKVQSVSGSLTPLPLYVR
                     GIDPSSVDGIWWIDRLGTELADKYPKITRIESIASLVRSYNSGVLPVSQAGLDRVLAA
                     IPAQERSLYQIDATTSIVIISIGSMTINEQRAFSDNVAAEIKWLEPPPGAEVVPTGDF
                     SLYVILTEQVVKNKDRMTMLGFILIFVLLLLIYRKAVALTPLVPIICVIGWNTLGMIA
                     LGQDYSILTAVLGSMTIGVGSEYTILVMERYLEEQRKTGDKIRAIQEAVRKIGSAVVV
                     SGLVTAAGFSALMLSSFPILSGFGLSTVILVIFSLLSASVIMPAVLALVGRQERT"
     gene            complement(6921..9035)
                     /locus_tag="PK679_06245"
     CDS             complement(6921..9035)
                     /locus_tag="PK679_06245"
                     /inference="COORDINATES: protein motif:HMM:NF021355.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-propeller domain-containing protein"
                     /protein_id="HPC55590.1"
                     /translation="MMHRFHPAILCSCLILAGVLGAACLSIPATTAPVSPEIRKFNST
                     AEIEQYLRDSMETSRDTLYRTMVPTIAATSPLPKESTGSEQASAIPVPYSTTGFSGGR
                     DYSKTNVQVAAVDEPDIVKNDDRYIYTISGQNLVIIDAYPAERASIVSTTEISDTPRN
                     IFVRGDRLVLFSTGTDRLDRTTGEDGTEGKVMPMPPYWRFPSFVTHATIYDIRDRANP
                     VVLKDYSVDGNYLDARMIGSLVYLVTQQQINPYRDAPVIVPVLREGTRTVIQPDVWYF
                     DNPEPQYIFTTITSLDIATGKERDAQTYLLGTGNTLYVSKDALYVSYPRYSPVIYRAP
                     GDLPLRSGAAGDSSGSSSVIPADFNTLPAEERESILESLRKGEEDAVLRQEADQTTTV
                     IHKIGIENGAITYRAKGEVPGALHNQFSMDEYGDNLRVATTSSVSSRRFGQYTYNNVF
                     VLDRNLKTVGELTRIAEQETIYATRFIGDKLYMVTFRRIDPFFVIDLSDPEKPRVLGK
                     LKIPGYSDYLHPYDATHIIGIGRETETNDWGGVSTSGVKIALFDVSDVESPRLLDKVQ
                     IGDAGSDSAALQDHHAFLFDRAKNLLVIPIRAVTAEPVAKDGSISPRPQVWYGAYVFG
                     LNPETGFTLRGTVRHGSSDTGYSYYGSPASEVKRSLYIDNVLYTLSAKQVKANPLDDL
                     ATTLATIPLPPAGDIYYPDVME"
     gene            complement(9300..10094)
                     /locus_tag="PK679_06250"
     CDS             complement(9300..10094)
                     /locus_tag="PK679_06250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate decarboxylase family protein"
                     /protein_id="HPC55591.1"
                     /translation="MFRLDKNSTYMMPAHFGGGAFDPTYKATMQAVLLNMAFETDRAA
                     LEQYIPEELELLSPEVQISLNQLTEINWLSGGHYNLVGVSSPVRFNGKKDHVDASYPL
                     VMWENQTAPILTGREQTGVPKIFADIENLHILKPYYASSVSYEGNTFLTMNFEAGGEI
                     TGKDFERVKSQMKVLDLIGWRFIPKVGAPGADLSQFIYFPQWMEVRKAWTGTGTFRWT
                     ELTPMQNPRQYHIISALASLPVKKMTRAILAEGEVVIDTLHSRVLE"
     gene            10258..11226
                     /locus_tag="PK679_06255"
     CDS             10258..11226
                     /locus_tag="PK679_06255"
                     /inference="COORDINATES: protein motif:HMM:NF012517.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HPC55592.1"
                     /translation="MGIKIGFFSIGDAFSPAECLKYSKLAEKIGFDSLWVEDHLIAMP
                     GGEECSFAWTVMSSALQATNKVPFITGVTAPIMRYHPAIVAQAFATMGSMYPGRVGLG
                     VGTGEPPNEMAVYGGQWPSNATRLEMLEEALTVIRKLWTSDTPISFSGKYYTLNKAVL
                     LTKAKVRVPVYVSAIGPRAADLAGRMGDHVISIANNPRYIRDELWPAFEAGARAAGKD
                     PGKMERVGHFSYIYDPKGEVNPDYIQHDAGTIQGGAMSKAFASRMITVFHSADDCIRR
                     IEEMGRMGYTHLAIADQFMALPKEHRPSIGTEESLNFWKDVLPHVR"
     gene            complement(11455..12210)
                     /locus_tag="PK679_06260"
     CDS             complement(11455..12210)
                     /locus_tag="PK679_06260"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HPC55593.1"
                     /translation="MSLPPLPPLFYQIFESLPRQGPGCPEATRKVFSLVPPLPGDAQI
                     LDIGCGSGAQTRDLAALTTGTITAVDNHQPFLDAIDAWAEKAGTAQRVKTVCASMNAL
                     PFEQESFDLVWSEGAIFIVGFGEGLNLWKPLLKKGGYMVVSDADWFEPDPPAELVKWW
                     ESEGYIPVTEEEMKERVKRAGLRLVATYRLPEAGWWDNYYVPLLARIAALRKTHGSDP
                     GNAALLDALMHEADMYRKYKRWYGYTFFVMQKT"
     gene            12481..12780
                     /locus_tag="PK679_06265"
     CDS             12481..12780
                     /locus_tag="PK679_06265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HPC55594.1"
                     /translation="MVKKKIETVCGFSCSDCDHHEKDCPGCEKVTGRPFWTAFVNIDQ
                     CPVYECCTTLKKLPHCGKCPELVCERFFRFRDPERTDEQAAAALAAAEKELRARG"
     assembly_gap    12983..13082
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(13092..13484)
                     /locus_tag="PK679_06270"
     CDS             complement(13092..13484)
                     /locus_tag="PK679_06270"
                     /inference="COORDINATES: protein motif:HMM:NF015639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC55595.1"
                     /translation="MEQVCRQCGRCCERWGWGQPGTVTDLVPWVRAGREDILRHVSVR
                     LSGGRWVSGDSLREGDLSSVVAVRYWQDTGGRPLRYCPFLGRRDDGLAYCAIHAVRPA
                     VCREYAPWNCADGDYLQVKCPACRDRVP"
     gene            complement(13715..15544)
                     /locus_tag="PK679_06275"
     CDS             complement(13715..15544)
                     /locus_tag="PK679_06275"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HPC55596.1"
                     /translation="MRLLLIHSDFIEFEAKQKTGMAEEDQPLKGFAEDALTVFCAVES
                     GDEDDMAGVVEQAGAEISKTADQLSVENIVLYPYAHLSSDLARPDAAVEALKMLEHLL
                     VDIGFEVKRAPFGWYKSFRLSCKGHPLSELSRTILPPEGGAKKEKKEVTHEFFVLTPD
                     GKRHDAKAFMDNSAFGCLVRKELGEPAEGGGEPAHVELMRGKELVDYEPVSDVGHLRW
                     LPKGKLVRDLLADYVLSRLLPYGASPVETPVMYDLADRAIYEHADKFGERQYRFRSGT
                     RNMMLRFAACFGMFSIMRDMHISPNTLPMKMYELSTYSFRHEQKGEVIGLKRLRAFTM
                     PDMHTLCLDMPQALRCFEEQLLMGWETGRDFGTELVGVIRCTRDFYNEYSDWVAKMVQ
                     VSGRPLLIEILSERVHYWVAKVDLAAIDGQGRPIENPTVQIDVESSQRFNIKYHLDGK
                     EVHPPILHCSPTGSVERVICAILESCAKQDVPRLPTWLSPTQVRVIPVAERHLEYATT
                     VTRELNAGRIRADLDDRDESVSKKVREAAVDWVPFVVVVGDSEVESGRLTVTIRSRSE
                     PQKPFKETFTLPELVAAVREEVGDKPFRPLYTPVHLSKKPRYI"
     gene            complement(15610..16167)
                     /gene="dcd"
                     /locus_tag="PK679_06280"
     CDS             complement(15610..16167)
                     /gene="dcd"
                     /locus_tag="PK679_06280"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009394 - 2'-deoxyribonucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HPC55597.1"
                     /translation="MILVDWQIVDRIRRGFISVEPFDPGLVQPNSLDIRLGNHFVWYE
                     AGDAVIDPYVAETVVEGTRETVADSIVLAPGQFMLAETLEVIGLPDNIVASIEGKSSI
                     ARLGVELHQTGGWIDAGFRGSITLEMCNVNARPVRIYAGMPIGQLVFYTTEKALSPYN
                     LRKDAKYMDQRQATLSRYHQNIRDI"
     gene            complement(16290..17258)
                     /locus_tag="PK679_06285"
     CDS             complement(16290..17258)
                     /locus_tag="PK679_06285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HPC55598.1"
                     /translation="MKRALVPGLACLLLVAVLSCSGCSTTGPAGTAPDVRTPADLAGF
                     VSHAAHYAESSGRDAALATFSQKTGPFSRGDLYIYAYDYNGTLLADPSQPEAVGTNRL
                     DRTDVRGLPVIRIGAHVASGGGGFIAYLDPAPASGALNESHGESSVPKIGYVCPAGSD
                     MWIGSGLSLSDLADTGPRGMPPAIGNMTGLVRRGAEYGRKHGDDAAFAAIPDASGMFV
                     DGEGHYLYAYDYNGTLLAHPHLGGAVGTNLIGLADPFGMETIRALADTARSGGGFIVF
                     VWPNPGRENREELKIGYVLPVNERWWVGSGVYLSEITGVDTSFTPP"
     gene            complement(17352..18098)
                     /locus_tag="PK679_06290"
     CDS             complement(17352..18098)
                     /locus_tag="PK679_06290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HPC55599.1"
                     /translation="MPEIRFVLVEPLYEGNVGFAARAIKNFGFSRLVLVDPCPLGDDA
                     LARAAHASDVLKAARVCSLEEVFSESDITVATTGEVGKTICHPMRMPYCSPRELREMI
                     GDVAGTVSILFGRENWGLNNEEMRRSDIVCTIPTSPDYPILNLSHAVAIIAYELAGLP
                     RGEYLLAGREQMEHLYRHIDQYLTLINHPAFKREGTMLMMRRIFGRARLTAREASTLH
                     GLMRRSEWHIRHDVRTESPPGEDDSGDADE"
     gene            complement(18181..18867)
                     /locus_tag="PK679_06295"
     CDS             complement(18181..18867)
                     /locus_tag="PK679_06295"
                     /EC_number="2.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerol geranylgeranyltransferase"
                     /protein_id="HPC55600.1"
                     /translation="MHINWKSWTHVTKLDPDRQLTPEQIQGVVTSGTDALMLSGTLNV
                     TRKNMQELLRQVAAYGLPLVVEPAGPEAVISEGADLLFVPSVLNTKNVEWIVGKHTQW
                     VLQQEIDWERVVPEAYIVLNPNSSVGKVTAANCALSPKEAAAFATVADRYFHFPIVYI
                     EYSGMYGDPAVVRAVSGALESSVLYYGGGIDSPEKAAEMAQYADTIVVGNAVYEKGID
                     ALRATVRAVI"
     gene            complement(18882..21722)
                     /locus_tag="PK679_06300"
     CDS             complement(18882..21722)
                     /locus_tag="PK679_06300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HPC55601.1"
                     /translation="MHLIVAEKNISARRIASILAGEKNVRELKDGGISSYSFNGTTVV
                     GLRGHVVEVDFVEGYSNWRSESKTPRSLIDAPTIKVPTEKKIVALLQKLAKKATRVTI
                     ATDFDTEGELIGKEAYELVRAVNPSVPVDRVRFSAITPGEIRHAFASPTEIDFALASA
                     GEARQVIDLMWGASLTRFLSLAAKRGGANILSVGRVQSPTLAMIVDREREIEAFKPEK
                     YWQLRLLTGKGGEDIEARHTTSRFHTFDEALAAKERSVPPLVVTSVVEGTKVDRAPSP
                     FDTTSFIVAAARLGYSAANAMRIAEELYMNGYISYPRTDNTVYPATLDLGSVLSAIRP
                     TVFRPDVEWVMANQRPVPTRGQKVSTDHPPIHPTGPAGREELGEERWKLYELVVRRFL
                     ATLSPDARWRTMKVMLSAGGEPYTVTGGQILEPGWRKVYPYSAATEYVLPGLKEGEVL
                     PLREVRMEEKETQPPPRFTQSRLIQRMEELGLGTKSTRHEVIQKLVSRKYVEGNPLRP
                     TLVGRAVIESLENHADTITRPEMTQTLESHMQQIKERARKSDDVVQESRGMLHQVFDQ
                     LEAHEQEIGDEIREQTAEELRLGPCPVCGHDLRIHHVRNQTQFIGCTHYPECTFNIGL
                     PATMWGYALRTDRTCPEHGLYHVRLVRKGSRPWEIGCPLCHQIASLRETLALLPSAGA
                     DLAEKMVAARIYSVQDIIGTPDEKLAEIPGITPERARQIRKEAEEALDLLRRRSDCRK
                     FVRSRIAPRKGRSPGTIVKKLAQAGINGIDDLGKADPAVLREAGLSQKEIDALQAGAR
                     REVGERTLRTIGIPPASLKKYLGAGFVTPESLLTIHPLAIAEKTGISPDTVFRHVETV
                     ARHLGKPVPEKVTAAKFRRGREDLLSVPGMTPQVYSQLLSAGVFDRETLHGLDESLIS
                     VRSGLPRQKIAALRKAAPLTKKKRSGEDIIVI"
     gene            complement(21731..23164)
                     /gene="gatB"
                     /locus_tag="PK679_06305"
     CDS             complement(21731..23164)
                     /gene="gatB"
                     /locus_tag="PK679_06305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HPC55602.1"
                     /translation="MNVIVGLEIHCQLDTKTKLFCGCSTDYRTDGPNTHVCPVCLGLP
                     GSLPVLNRKAVEYALRVAKALHCTVPEESVFARKNYFYPDLNKGFQITQYDKPLAVSG
                     YLDIEGDEGEKRVRITRVHMEEDPGRLVHKGGTDRPRYSLVDYNRAGIPLIEIVTEPD
                     LRSPREARRFLNKLRATLEYLGVFDSEKEGSLRVDANISIEGSERVEIKNITSYKGVE
                     KALTFEVTRQKNALRRGQKIVRETRHFVEARGVTTSARSKEMEQDYRYFPEPDLCPLR
                     VADWVDGIVLPELPDARRQRFMDQYGLSLIHARTLTGDLRLAEFYEKVAGTDPALAAT
                     WVADTLLGELNYRDMSISSVPPDVFSGLLSLVRARVITDRNGVDVLRVLLDELKEKGT
                     CESPEACAERLGLRALPADSAGGDDPVTKAAREALAENPRAVEDYRNGRKEALNFLVG
                     QVMRKTRGCAKPADVNRVLASLLGEGA"
     gene            complement(23161..24465)
                     /gene="gatA"
                     /locus_tag="PK679_06310"
     CDS             complement(23161..24465)
                     /gene="gatA"
                     /locus_tag="PK679_06310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HPC55603.1"
                     /translation="MAEGMLTFSPDDRYNAFLRTVSPARYGEGRLRGIPVAIKDNIST
                     AGIETTCGSRILSGYVPPYDATVVSLLKKEGAAIVGKTNMDEFGMGSTTENSAFGPTK
                     NPRDETRVPGGSSGGSAAAVAAGLVPLALGTDTGGSIRCPAAFCGIVGLKPTYGRVSR
                     YGLVAYANSLEQIGPMAADVAHANLLMSVIAGHDPKDSTSLDAPYSHTPSMEIRGTRI
                     GVPEEFFGEGVDPRVASVVWDAISLLERKGAEIITCRMPSMAYALAAYYVTCMSEASS
                     NLARYDGVRYGPPADVRKPWHEAFQERRREGFGLEVRRRIMIGTFALSSGYYGKYYAK
                     AQAARRNVREDFGRLFAEVDVIAGPTMPTVAFRFGEKSDPLAMYLSDILTVPANLAGV
                     PAISVPCGKVEGLPVGLQIMGRWMEDERVIDVAYAYEQGANP"
     gene            complement(24465..24734)
                     /gene="gatC"
                     /locus_tag="PK679_06315"
     CDS             complement(24465..24734)
                     /gene="gatC"
                     /locus_tag="PK679_06315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HPC55604.1"
                     /translation="MITEKDVEHIGMLADIAILRGELEEFTASFNRILEYFDILDQVT
                     GEEKDGGAAVNVLREDEVVPSLSPQDVLSNAKETEDGFFRAPRVM"
     gene            complement(24939..25883)
                     /locus_tag="PK679_06320"
     CDS             complement(24939..25883)
                     /locus_tag="PK679_06320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase-related protein"
                     /protein_id="HPC55605.1"
                     /translation="MVLPPGEVRARLLQDPLAASSFGGEFYLSWDGYRARDALGIVPG
                     PIPPGTILDGDRVIGKVCPRFRKTGLAEAIVTAVQLRSDRGVVALSGGVDSALVAAIA
                     RRPCIVAGMEGSFDLEGGRQAARELGLDCTEVTVTPADVEDAVPGVLSLIPEKNPLDL
                     SIALCWHFIARSARDAGHDRVLSGQGADELFGGYSRYLADRDTDALLAADFARLPGQI
                     ARDQAVATGEGVLISYPYLDARVIAAARAIPAGEKVSGGIRKRALRKVAAEFLPPGIA
                     WKEKKAMQYGSGIWRELQRLARKRGCRTVGEYLARVPG"
     gene            complement(25928..26281)
                     /locus_tag="PK679_06325"
     CDS             complement(25928..26281)
                     /locus_tag="PK679_06325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55606.1"
                     /translation="MRNPGSFVLQAGRQGRAVLSLALLVLALNAAVAGVSAVVPPGAP
                     DIVEPQPTQTPFTQASFTQPAPAHGYSVVGDSFSVPLPAWTVIGLVMIGAVVVAFFLL
                     RRPDEYVPRSKRLRK"
     gene            26319..27575
                     /locus_tag="PK679_06330"
     CDS             26319..27575
                     /locus_tag="PK679_06330"
                     /inference="COORDINATES: protein motif:HMM:NF024777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamG domain-containing protein"
                     /protein_id="HPC55607.1"
                     /translation="MEMPGVLMENRGLKGEEGISATVSVILMVVLVIGIALVLWSVFM
                     GYPSILHHTVYIASEAKAEEIVQPGGLPMEVVAFTIREAEPFHFAGQNPPVAGKEVLI
                     KVVTPDGRTIYPTPFISGGNLEGKTLYIFPNSTGFSSYCDYIVSDTAPAGRLKPFVTG
                     TWVIQLIDPEANLLISSDDRARITKGTTAYPVAGGIPGNGVYRTDCTPLASSINGNPV
                     RGNTGAPMNMSYLSFDGDDWIAYADDPTLTFTGDLTISIWLKPQDVTSWKQVIGKGLQ
                     ISTNKEDKNYDLYLINDKVYFEWDDRVTGTHYHVMTNAPAVTGGSWQYVNLIVDGGKP
                     KIYVNGLSQPFTYYQSNVPGTNPITNPSQIPEVRLKDNDHPMTMGKQASTSYPFYYKG
                     SIGSFALYNRGLTDAEIQENYQTYRA"
     gene            27679..27996
                     /locus_tag="PK679_06335"
     CDS             27679..27996
                     /locus_tag="PK679_06335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HPC55608.1"
                     /translation="MSRFVRGDVVLVPLRIGGAGPEKVRPALVVGGEGERLRVIPVSC
                     TPSRDTPSVPLAPMDFCRGGLDIVRESYLLPAHAAWVFHKAVIGKKGRVSQEFLSRFV
                     GVM"
     gene            complement(28031..28165)
                     /locus_tag="PK679_06340"
     CDS             complement(28031..28165)
                     /locus_tag="PK679_06340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55609.1"
                     /translation="MGLLNPVEMPGSVVRVVIFLRVIPVTGDQKGTAPRGKRAEGRVA
                     "
     gene            28186..28674
                     /locus_tag="PK679_06345"
     CDS             28186..28674
                     /locus_tag="PK679_06345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deaminase"
                     /protein_id="HPC55610.1"
                     /translation="MRTNRHQYFLDLALRCAHQGTCLRRNFGAIIVDEFHTIVSTGYT
                     GAPRKQMDCTELGRCWRKDHNIPSGSHYERCRSVHAEMNALLQAGKLARNCTLYLAGF
                     EVDTGELTRIWPCFLCSKMIVNSGIRTVIMRTGPETFQEMDPMVLYQMRSREALGDGG
                     PA"
     assembly_gap    28717..28816
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(28817..30313)
                     /locus_tag="PK679_06350"
     CDS             complement(28817..30313)
                     /locus_tag="PK679_06350"
                     /inference="COORDINATES: protein motif:HMM:NF012707.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HPC55611.1"
                     /translation="MRISMRSLCGLAIPLVACALLGIFVLAPGCMEQQTPGQKVVSGC
                     PEGELLLLTEEIYPYSTVDSAGTPGGTSVAVVREMVRRSGCSARIEVHPWNTSYEKAL
                     RTPGAALFPTARTPDREPLFLWAGPIGTFEYVLYARSDSGIRLESLEAARAAGTIAVV
                     EGDARHTFLLANRFTDVKTYPTDAECLAALQNRSVSLWLGSSAAAPGIMAETGVAEGT
                     VIPVYTLHRVDLYLAFQNTTSPATAKKFQEVLDAMKADGTYARLTGAGEGKGETPATA
                     AQGGVPAKTLLSALSSLVGTRMHGISAALEALALTSDVRSGDWERVRPLLVRLESDHP
                     EARFWYARPDGSYYTTVDNLTSANIRDRPYFPVVLGGKTSIGTVVLSRTTGKNTAIIA
                     VPVTAGGQVTQILGTSVYCDSLGDALARSLPLPDGYYFFILDSSGNTVLDSLPDRTFS
                     LAGDPAALAALQARDEGEVSYRFEGASHRAVFTTEGVTGWKAAIGWRE"
BASE COUNT         5778 a         9266 c         9209 g         6045 t
ORIGIN      
        1 tccggaccaa acaacaggat ctcactacga gggagggggc atacattaat caaccgcccc
       61 gttctccggt ctgctccctc ctgcctcccc gtggtgaaaa cctgtcaggc gggtgctgga
      121 atgaaactga ccgtattccc ggctggagat gaccggtttt tagtttaaag gagagaattg
      181 atatcaaatg ccctgtgtcc ggagggaaaa gaaaaaaagc cggagttctg gctggaagat
      241 cacccacccc tatctcttcc tcctccggag tctccatacc gcatccgcga tgagcacgat
      301 cgctcctgca ataacgatga gggcgaagag atgtccacag gaaggtgatt acaaatgggc
      361 gatcatcaag gcacatagta ccctgtttca cgcagccatg tcgcccgtca tgagtgcagg
      421 ctatatcggg aaagagccat gattgtctta tcgttgaatg atcccggata cacaaagatt
      481 gatgccatat cagaccgacc atctgcataa ttttcctgag gaaatatcat gaacagcatc
      541 gaaacggatg tcagggagat taaagaaaat atcagagcac tcaccgaaaa gatcgaggcc
      601 ctcctttacg agagggaggc ccttgcaatg atgaagctct ccggacggtc actctctgct
      661 ttcctggacg aagagcctga cctctacacc gtcacggaca tcaaggttgt gtaccgatga
      721 agggaaagat cgtcctgata ccctttcctt tcactgatct caccgcgacc aagcttcgac
      781 cggcgctcgt cctccacgag ggagaacacg atgttgttgt cgcctttatt tcatcaaaaa
      841 ctcccgcgaa aacggttgaa tccggtatcc aaataacctc tactctccca ggtttttcaa
      901 aaacaggtct caaggtcgat tctgtgatca gattggacaa ggttgcaacg attctgaaag
      961 acctgatagt cggtgaaatt ggagaactgg atgatgacct cagagcagac gtcaatgcaa
     1021 aaatcgccac acttttcaga ctctgatcag gacagaggcg gaacgcaata tccattttta
     1081 ttccctcttt ttaggataaa gagagatcca aaagagaatt aagggtttta tcctaatcca
     1141 tgcgataacc gcgctctcct gcgtaaagta cagctgaaat tcgatcgaaa ccagaattat
     1201 gcaagataat accttaaaaa aagatcgtac ccgggggaga attcatatct ggacgagctt
     1261 gagagattcc aattattgta gatcccaaag aaccaaaatg gcgatagtga aaggggatta
     1321 aaatcaaccg ccccgttctc cggtctgctc cctcctgcct ccccgtggtg aaaacctgtc
     1381 aggcgggtgc tggaatgaaa ctgaccgtat tcccggctgg agatgaccgg tttttagttt
     1441 aaaggagaga attgatatca aatgccctgt gtccggaggg aaaagaaaaa aagccggagt
     1501 tctggctgga agatcaccca cccctatctc ttcctcctcc ggagtctcca taccgcatcc
     1561 gcgatgagca cgatcgctcc tgcaataacg atgagggcaa ccgggttcga ggtgatcgca
     1621 tcgagtccct ccggttcccg gatcccgatc ccaaagctca tcgggtccga gagcatgagg
     1681 gcgcccagct cgtcgcggta cttgatctcg gaatcaatga cgtagcgttt cccggggatt
     1741 gccgcatcag cagagataac aaacagggct gtcacggtct caccgggacc gatagtcccg
     1801 agatccaccg aatcgaccga tggaacgagg acgtggctcc cgatgatccg ggcccgggca
     1861 tcgtaggcag gggtatcccc ggtattcctg aacccgacgg taattgccct gtcccggccg
     1921 ggagtaatca ccacatcctg gttcaccacc tcgaataccg ctccccgcaa gacctctatc
     1981 ccgaggggga cttcacgggt agcccggatc atacccgcat cgtctttgta ttcgccaatc
     2041 aggacggcgg ggtatgaccc ggcagcggta tgctccctga cagctatccg tacccgcagg
     2101 ggtaccacgt ctccgggcgc aaacttcccg atgaatacgc tgtcgtccac catccggaac
     2161 gtcgtgttgt cggccgggac gacccggagc gtaacggagt tccctgtcgc atatccggtg
     2221 ttttcgacca gggcggtcag gtacccctgc gagccgggca ccatgttctc gcagctgacg
     2281 ttcctgatcg ccggcctgac atcccccctg acccggaagg tgacaggaag tacctgctcc
     2341 ttatcgcggt acagcaggtc gatggtgctg aattgatcgc cgaccatggg gatggcatag
     2401 acatatctgt acttcacgac aaggggaatc gtgtggaaac cgggagtcgc gttctggaac
     2461 acggtgccac tgactgtcag acgcgccttg ccccaggacc cgatatcccc ggccataacc
     2521 gggaggcttt tgatagtcac gggagcgtct cccgcctgcg gccagacagt aacaccgatg
     2581 gcagtgctcg gatcgtatgc cccgggagaa agccgcgggg caatctggac ggcggtgtcc
     2641 ctgcccttgt tggtcaggac aaccgtcatc gcgaatgcat cgccggggta atactcggta
     2701 acgccttccg catgggcgac gaggtccggc tgggcacctg tatcaaggta gatgaacccc
     2761 agtgcagaca acggggggca caagagggcg aggatgagga agagccccat gagaacggag
     2821 atggcggcag gggagcggga tgatcctttc cccgcagaac gatggaccat ggaccctctc
     2881 acttcgcagc agccgatttc ttccggtacc acaggtacgc tccccctccg gcaaccacga
     2941 tgatgagaac gattgcgatg ggcaggacgg acccgccctc ccgtacctca accacgacgg
     3001 gtatattgtc cgaggtaaag gaggtctggg aggaatcgag gtacctgaca tccgagtcga
     3061 gggagtacgt cttgatggtg gcatctgccc ccgtcttgat ggcaaacgtt gcggttgcgg
     3121 actcgcccgg cttgaggtca ccaaggtatg ccgtgtcgtc ctcgctcgtg aaaggatcga
     3181 taacgctgat acgggcctgc gcactgtata ccgtcgagtt gccggcattc ctgtacgtca
     3241 cgctcatggt attcgtctca ccggcgtgga tcaccggggg cgggctggta acctcgaacc
     3301 tgaccttttc agaaaaggac acccccgcgc ttgacatggg cgaacggacc atgttcccct
     3361 cgaaatccct gtagacagcg tagagcatga cgggagcagg ctgcgccggg tcagcatcac
     3421 gcgagacgga aaccttgaaa cggggctgca cggtgccgcc cgggggaagc gtccccacgt
     3481 ataccccgtt cgagaacggc acgatcgggc ttgcaccttc gggcacgagg taaatggatg
     3541 tcctgtcccc tgtatcctgc cccgtgttcc tgatcacaaa cgttatgtaa ccctcgccac
     3601 cggcatggag gtcgctgaca gatacgtcct ccacggacag gaccacaacc ttcctgatca
     3661 cgatggggac aggcagcgag acctcgacgt tcctgaagga gtattcgagg gtatcggtgc
     3721 ctgactgttc cacctggggc acgtaactgt aggagatgac tgcctgcatc gtgtagttgc
     3781 cggcctttgc atcctccgga acctccacca cgaaatggac ggggataacg accccggacg
     3841 gtatatcccc cacgttctgg gaatcggatt ttaccctgac gggggcatca ccgggcacga
     3901 gtctgaccct tgcgaacttc gccgtcgtcg ggaggtactg gggttcgagg gtatatgcat
     3961 tataaaactg catcgtgagg atccccttgt tctcgatgac aagcggaagg tctgcagtcg
     4021 tcccggggat catctcatcg tttccggcaa gagaaacgga cagttcgggc cctcccgagt
     4081 agtatttata ccccgccgag cacggaccgg tacagaacgc aagggcggcc aggaaaacca
     4141 ggaaaatgaa taaaatgcgg tgcaggcaga aacaacgcat aggacatctg tctccttcac
     4201 agttttgtta agattgaaaa aaagattaag gtaacgaagc atggcgcaac ccgttggggg
     4261 atgtggttcc ggatggagat taatcgcaat cctcattata aatcatttct ccatttctac
     4321 ggtaaggaaa ggttggtccc tgcatgaaga cggaagacgt gtttgggggg attgcggtct
     4381 tcgtaaaccg ccacccgaag gagatcttcg tcgtgatgct cgttcttgcc gcaatctccc
     4441 tcttttttgc agggcatatc cccacccagg cactctccga cgagtacatg gacaagcagt
     4501 cccccgcagg gatcatttac gacctgtata acaaccgcta cgggcaggac acctacatcc
     4561 tcctgatcaa gacccctgac cccggggacc ccgtactgct gaaccagctc ctcgtccttg
     4621 aaaagcagct gagccgcatc agccacgtcg attccgtcca ctccgtcgcg gacatcgttg
     4681 cacagtacca tggaggggcg atccccggca cgagcgccga agtgtgggca atcattgacc
     4741 ggctgccccc ggatatccag aaaaagttcg tgcctgaccg gcagacagcg cttggctatg
     4801 tccttatcga gcagggagtg tccacggacg cctcccagaa catcgagcct ttcgtcgtga
     4861 ataccgtcgg gcaggcgacg cttcccccgg gagtatcgat cgagatcacc gggaacactc
     4921 cctacacgct ccagttcgag ggcgccatga tggctgattt cggcgtgctc atcattgcgt
     4981 gcatcatctt catgctcatc gtcatgtaca tcctgtactc gaagatccgg ttctggatac
     5041 tccccatcgt tctcctgatc ttcggcctct tctatacgtt cgggatcatg ggggcgttcg
     5101 gcatcccggc aaacgacggg gccatcgcgg cgttccccat actgctcggc ctcggcatag
     5161 actatgccgt ccagttccac atgcgctttg acgatgaacg ccgccaaaag gagatctctc
     5221 ctgcactcgc agagaccctg aagcataccg gcccctctgt cctgatcgca ctcgcctcca
     5281 catcgcttgg atttgccgcg atgttcatca cccccatccc catgatccag acctttgcca
     5341 cggtgtcgat catagggata tcctgctgtt acctgacctc ggttctggga ttcggggcaa
     5401 tcgtccacct ggtctcctat gagccgaaac cccccggcag gggttttacg taccggctca
     5461 atgccgcgta cgagagggtg ctctcgacag tcgtttccgt ggttgtgaag atcgccggac
     5521 cggtggtact ggtcgcggtc gtcatagccg cggcgggcat tgccctcgac agcggcatcc
     5581 ctgtcgatgc atcgcagaag tcaatggttc ccccggacct cccggcacag ctcgttgccg
     5641 acaaggtcca gtcggtgagc gggtcgctca cgccgctccc gctgtacgtc cgggggatcg
     5701 atccctcctc cgtggacggg atatggtgga tagaccggct gggaactgaa ctggccgata
     5761 aatacccaaa gattacccgt atcgagagca tcgcctcgct cgtcaggtcg tacaattccg
     5821 gggttctccc tgtcagccag gccgggctcg accgggtcct cgcagccata cctgcacagg
     5881 aacgcagcct ctaccagatt gatgccacga catcgatcgt catcatcagc atcgggtcga
     5941 tgacaatcaa cgagcagcgg gcgttctcgg acaacgtggc cgcggaaatc aagtggctcg
     6001 agccccctcc cggggcggaa gtcgtcccga caggtgattt ttccctttac gtgatcctga
     6061 cagaacaggt cgtgaagaac aaggaccgca tgacaatgct gggtttcatc ctgatcttcg
     6121 tcctgctcct cctgatttac cggaaggccg tcgcgctgac ccctctcgtc ccgattatct
     6181 gcgttatcgg gtggaacacg ctgggtatga tagcactcgg ccaggactac agcatcctca
     6241 ccgctgtgct cggttcgatg acaatcggcg tcgggtccga gtacaccatt ctcgtcatgg
     6301 agcgctacct cgaggagcag cggaagaccg gcgacaagat cagggctatc caggaggcag
     6361 tcaggaagat agggtcagcc gttgtcgtct caggtctcgt gaccgccgcc gggttctccg
     6421 ccctcatgct gtcatcgttc ccgatcctct ccgggttcgg actgtccacg gtcatccttg
     6481 tcattttctc cctgctcagt gcatccgtta tcatgccggc tgtcctcgcg ctcgtcggga
     6541 ggcaggagag aacgtaaccc accctgggaa atcgtgaggt cttgttcatc gtcgatcgcg
     6601 atgacgacca tcccctggat ccccttgccg gatccgcgga ccgactcccg ccggagtgcc
     6661 cccgctttcg ttctgcaagg cttggcacgc aacgatgagc aatacgcctt ttggtccggc
     6721 atggctcccc catgggggcc tgtgtgatcc agggggagaa aaggcaccat tccccctgga
     6781 acaaatgcat tcacgcacca attgttctga tgagagttcc aggatgttct taaaatggcc
     6841 attaagccgg attcaaaact tttttttcaa caaaaatgag tatcgcacct cactccaaaa
     6901 atattctcct ttcctccccg tcactccatg acatccgggt aatagatatc ccctgcgggg
     6961 gggagaggaa tcgttgcgag tgttgtggca aggtcatcga gcgggtttgc cttgacctgt
     7021 tttgcagaca gggtgtagag cacgttgtcg atgtacaggg accgcttcac ctcggatgcc
     7081 gggctcccgt agtaagaata accggtatca ctgctgccgt gccggacagt gccgcggagt
     7141 gtaaaaccgg tctccggatt caggccaaac acgtatgcac cgtaccatac ctgcggacgc
     7201 ggggagatag agccatcctt tgcgaccggt tcagccgtga cggcccggat ggggatcacg
     7261 agaaggttct ttgccctgtc aaagaggaag gcatggtgat cctggagagc ggccgagtcg
     7321 gaccctgcat ccccgatctg caccttgtcg aggagccggg gagattcgac gtccgagaca
     7381 tcgaagaggg caatcttgac cccgctcgtg gagacaccac cccagtcgtt tgtctccgtt
     7441 tccctgccta tcccgatgat atgcgtcgca tcgtaggggt gcaggtaatc ggagtatccc
     7501 gggatcttga gtttcccaag gaccctcggt ttctccgggt ccgagagatc gatgacgaag
     7561 aacggatcga tacgcctgaa cgtgaccatg tagagcttgt ccccgatgaa ccgggtcgcg
     7621 tagatcgtct cctgttcggc gatgcgggtc agttcgccca ccgtctttaa gttcctgtcc
     7681 aggacaaaga cgttgttgta ggtatactgg ccgaagcggc ggctggagac gctcgatgtt
     7741 gtcgcgaccc ggaggttgtc gccgtactcg tccatcgaga actggttgtg gagggccccg
     7801 ggcacttcac cctttgccct gtaggtgatg gcaccgtttt cgatgccgat tttatggatg
     7861 acggtggtgg tctggtctgc ttcctgccgg aggactgcgt cctcttcgcc cttccggaga
     7921 ctttcgagga tggactcccg ttcttctgca ggaagcgtgt tgaagtcggc cggaataacg
     7981 gacgagctgc cggaagaatc accggcagca ccggaccgga gcgggagatc cccgggcgcc
     8041 cggtagatca cggggctgta gcgcgggtag ctcacgtata gtgcgtcttt tgagacgtag
     8101 agggtgttcc cggttccaag caggtacgtc tgggcatccc tctccttccc ggtcgcgata
     8161 tcgagggacg taatcgtggt gaagatgtac tggggctcgg ggttatcgaa gtaccagacg
     8221 tccggctgga tgaccgtcct tgtcccctcg cggaggacgg ggacgatcac cggcgcatcg
     8281 cggtacgggt tgatctgctg ctgggtgacc aggtacacga gcgacccgat catccgggca
     8341 tcgaggtaat tgccatcgac agagtagtct ttgaggacta ccgggtttgc ccggtctcgg
     8401 atatcgtaga tggtggcatg ggtcacgaaa gagggaaagc gccaataggg tggcatcggc
     8461 atgacctttc cttcagtccc atcctccccg gttgtgcgat ccaaacggtc cgttcccgtc
     8521 gaaaagagga cgaggcggtc tcccctgaca aagatgttcc gtggtgtatc ggaaatctct
     8581 gtcgtggaca cgatggaggc ccgttctgcc gggtacgcat cgatgatcac gaggttctgc
     8641 cccgagatgg tgtagatgta ccggtcgtcg ttcttgacga tgtcaggctc gtcgactgct
     8701 gcaacctgga cgttggtctt cgagtagtca cggcccccgg aaaaaccggt ggtcgaatac
     8761 gggaccggga tggcagatgc ctgctctgac ccggtggact ccttcgggag gggggacgtt
     8821 gcagctatgg tggggaccat cgtgcgatac agtgtatccc gggatgtttc catcgaatcc
     8881 ctgagatact gttctatctc ggcagtcgag ttgaacttcc tgatctccgg ggataccggg
     8941 gccgttgtcg cagggatgct caggcacgct gcaccaagca cgcctgcgag gataaggcag
     9001 gaacagagga tggcggggtg gaaacggtgc atcatgatct cccgttacgc agtatgggga
     9061 gacgacgaca tcaatctggc gtaaactgcg aaaaatatcg cagccatcgg catatacgtg
     9121 caggaaatct ccatttccgg acaggcggaa aaagggggaa aatttttccg gtctccgcct
     9181 ccccactttc ccctttgcag accaaaaggg ggacggcccc gtgacctgtc cggcggtccg
     9241 ggcggctttt cccaaaaaac cgtcccggga acgcctttgg ggggataggg aggagatggt
     9301 tattccagta cccgggaatg gagtgtgtcg atgacgacct cgccctcggc gaggattgcc
     9361 cgggtcatct ttttcaccgg gagggaggca agcgcactga tgatgtggta ctgccgcggg
     9421 ttctgcatcg gtgtgagttc cgtccagcgg aaggtccctg tcccggtcca cgctttcctg
     9481 acctccatcc attgcgggaa atagatgaac tgcgagaggt ctgcccccgg agcgccgacc
     9541 ttgggaataa accgccagcc gatcagatcg aggaccttca tctgtgattt cacgcgttcg
     9601 aagtcctttc ctgtgatctc tcctccggct tcgaaattca tggtcaggaa ggtgtttccc
     9661 tcgtaactga cggacgaggc atagtacggc ttgaggatat gcaggttctc gatatcggca
     9721 aaaatcttcg ggactccggt ctgttccctg cccgtgagga tgggggcggt ctggttctcc
     9781 cacatgacga gcggatacga ggcatcgacg tggtcctttt tcccgttgaa cctgacggga
     9841 gaagagacgc ccaccaggtt gtaatgcccg ccggaaagcc agttgatctc cgtcagctgg
     9901 ttcagcgata tctgcacttc cggggacagg agttcgagtt cctccgggat atactgttcg
     9961 agtgcggccc ggtctgtctc gaaggccatg ttcagcagga ctgcctgcat cgtggccttg
    10021 taggtgggat cgaatgcacc gcccccgaag tgggccggca tcatgtaggt ggagttcttg
    10081 tccaatcgaa acattttttt atcctgcaac tttttccgtg aaaatataaa agtctgatcc
    10141 atttttgttt ccggcacggt cttttcgtcc tgaccccggg aaaacattct tatgaacccg
    10201 tgcctcactg tttaacaaac tctcaaagaa tgttaaaaaa tgcgaagagg tcatgaaatg
    10261 ggaattaaaa tcgggttctt ttccatcggt gatgcctttt cacctgccga atgcctgaaa
    10321 tattcaaaac tcgccgaaaa gatcggtttt gactctctct gggtcgaaga ccacctgatc
    10381 gccatgccgg gcggggaaga atgcagcttc gcctggacgg tcatgagttc cgcactccag
    10441 gcaacgaaca aggtcccctt cattaccggc gtgaccgctc ccatcatgcg gtaccacccg
    10501 gccatcgttg cccaggcttt tgccacgatg ggttcgatgt accccggccg cgtgggactc
    10561 ggggtgggga cgggagagcc gccgaacgag atggcggtgt acggcggcca gtggccgtcc
    10621 aatgccaccc ggctcgagat gctcgaggag gcgctcacgg tcatcaggaa gctgtggacg
    10681 agcgatacgc ccatcagttt ttccggaaag tactacacgc tcaataaggc tgtcctgctg
    10741 acgaaggcaa aggtcagggt ccccgtgtat gtcagcgcca tcgggccccg ggcagcagat
    10801 ctggcagggc ggatgggaga ccacgtcatc agcattgcca acaatccccg gtacatcagg
    10861 gacgagctct ggcccgcatt cgaggcaggt gcccgggcgg caggaaagga ccccggaaaa
    10921 atggaacgcg tcgggcattt ctcgtacatc tacgacccga agggcgaggt caaccccgac
    10981 tacatccagc acgatgcagg aaccatccag gggggtgcga tgtcaaaggc atttgcaagc
    11041 cggatgatca ctgtcttcca ttcggcagac gactgcatca ggaggatcga ggagatgggg
    11101 cggatgggat acacccatct tgccatcgca gaccagttca tggcactccc gaaggaacac
    11161 cgtccctcca tcggaacgga agagagcctg aatttctgga aagacgtgct cccccacgtc
    11221 aggtagccat cgggatactg tcgtgccgca tccattgtgc gggacgcccg ccgggcgcat
    11281 gaggaggggc attctccctc ctttcaccgg gccgggaacc gtacttccgc ctcgcgggct
    11341 tttccttcaa aagccagcac atctggttcg aaggatgcaa accggggatt gaagacgagt
    11401 tttgttgcgc cttcccgtcg cacccggatg agccggcgcc actgatggcg tatctcatgt
    11461 tttctgcatc acgaaaaacg tgtacccgta ccaccgcttg tatttccggt acatgtccgc
    11521 ttcgtgcata agagcatcga gaagggcggc attgccggga tccgatccgt gggtcttccg
    11581 gagcgccgca atccgggcca gcagcgggac ataatagtta tcccaccacc cggcttccgg
    11641 cagccggtac gttgcaacga gacggagccc ggcacgcttc actcgttcct tcatctcctc
    11701 ttcggtgacg gggatatatc cctcgctctc ccaccatttc acgagctcgg caggaggatc
    11761 cggctcgaac cagtcggcat cggacacgac catgtatcca ccttttttca ggagcggttt
    11821 ccagaggttg aggccctccc cgaacccgac aatgaagatg gcaccctcgg accagacgag
    11881 gtcaaaagat tcctgctcaa acggcagggc gttcatggag gcgcagacgg ttttcacccg
    11941 ttgtgccgtg ccggcttttt ctgcccatgc atcgatcgca tccaggaacg gctggtggtt
    12001 atcgaccgcc gtgatcgtgc cggtggtgag ggcagcaagg tcccgggtct gagcaccgct
    12061 cccgcatccg atatcgagga tctgtgcatc gcccggaagc ggcgggacca gggaaaaaac
    12121 cttccgcgtc gcttcagggc agccgggccc ctgccggggg agggattcga agatctggta
    12181 aaatagcggg ggtaatgggg gtaatgacat gatgcatagt tgttttgcag gatgcattga
    12241 gtgctttgtg gtcagaagat ccccttatcc agatgggcgc ttttggagtg cgggcttcac
    12301 gcgggccggc tgcctgaaat ccggactggt gctgaccaaa caggttcaca tccggaatgg
    12361 aagcagccgc agaactccac ccgctcattt tctcctgcct tagccgggtc cttttcgctt
    12421 tttccatttt caccccgcgt atgccgcatt tttatgggag tgcaacaaag acaggtggat
    12481 atggtaaaga aaaagatcga aacagtatgc gggttttcgt gcagcgactg cgaccaccat
    12541 gagaaggact gtcccggctg tgaaaaggta acgggaagac cattctggac agcattcgtg
    12601 aatatcgacc agtgcccggt ttatgaatgc tgcacgaccc tgaagaaact tccccactgc
    12661 gggaaatgtc ccgaacttgt ctgcgagcgg tttttccggt tcagggaccc tgagaggaca
    12721 gacgagcagg cagcagcagc gctcgcagca gcggaaaagg aactccgggc aagaggatag
    12781 ggcacccggg gaacagccgg ggaaccaaac aaccgggcgg gaaagattaa gggaatagtg
    12841 gtgtcagcgg caatccaatc agtctgacaa gcaaaagaat gccggggggc tgtctgcctc
    12901 cctctcttcc atttaaggaa atgccccgct ccttcccgcg tgatggtcct gcaccggctt
    12961 tttaccactc ctgcacatga agnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13081 nntgctcccc ttcagggcac ccggtcccgg cacgccgggc acttcacctg caggtagtcg
    13141 ccgtcggcac agttccaggg cgcgtattcg cggcagacgg cagggcgtac ggcgtggatt
    13201 gcacagtacg caagcccgtc atcccgcctc cccaaaaacg ggcagtaccg gaggggacgg
    13261 ccccccgtgt cctgccagta ccggactgcg acaacggacg aaaggtcgcc ttcccggagg
    13321 gaatcgcccg atacccaccg gccgccggaa agccggaccg agacatgccg gaggatgtcc
    13381 tccctccctg cccggaccca ggggacgagg tccgtgactg tacccggctg gccccacccc
    13441 caccgctcgc agcagcgccc gcactggcgg cagacctgtt ccatcgtacc ttcccggtat
    13501 ggcgggaaac cgtcataaac ggtgcgtccc tgtacccggg tgaagggcgg catggcgtcc
    13561 ccggaagacc ggcgatcgtt ttttaagatc ggcccctgag aaaagaagac cccctcctcg
    13621 caaccagaag gtcacgatac tgcgggaaaa cagggagaaa cgactattcc tctctccgtt
    13681 gccatgagag ggaaaaaagt ttttaccggg tttctcagat gtaccgcggc ttcttcgaga
    13741 ggtgcaccgg ggtgtagagg gggcggaacg gtttgtcccc aacctcttcc cggacggcag
    13801 caacgagttc ggggagggtg aaggtctcct tgaacggttt ttggggttcc gaccgggacc
    13861 ggatcgtcac cgtcagcctg ccgctctcca cttcggaatc gccgacaacg accacgaacg
    13921 ggacccagtc gacggctgct tccctgacct tctttgacac gctctcgtcc cggtcgtcga
    13981 ggtccgcccg gatacggcct gcgttcagtt cgcgtgtcac tgtcgttgca tactcgaggt
    14041 gccgctcggc gacggggatg accctgacct gtgtcgggga gagccacgtc gggagacggg
    14101 gcacgtcctg cttcgcacag ctctcgagga tcgcacagat gacccgctcg accgatcccg
    14161 tcggggaaca gtggaggatc gggggatgga cttcctttcc gtcgaggtgg tatttgatgt
    14221 tgaaccgctg cgagctctcc acgtcgatct ggaccgtcgg gttctcgatg ggccggccct
    14281 gtccgtcgat ggcggcaagg tccaccttcg ccacccagta gtgaaccctc tccgagagga
    14341 tctcgatgag gaggggtcgc cccgatacct gcaccatctt cgcgacccag tcgctgtact
    14401 cgttatagaa gtcccgcgtg caccggatga cgcccacgag ttcggtccca aaatccctgc
    14461 ccgtctccca tcccatcagg agctgctcct cgaagcaccg gagcgcctgc ggcatgtcga
    14521 ggcagagggt gtgcatgtcc ggcatcgtga acgcacgcag ccgtttcagc ccgatgacct
    14581 ctcccttctg ctcgtgacgg aacgagtagg tcgagagctc gtacatcttc atcggcaggg
    14641 tgttggggga gatgtgcatg tcccgcatga tggagaacat cccgaaacat gcggcgaacc
    14701 ggagcatcat gttccgcgtc ccgctcctga accggtactg gcgttccccg aacttgtcgg
    14761 catgctcgta gatcgcccgg tcggcaaggt cgtacatgac cggggtctcg accggggacg
    14821 ccccgtaggg caggagccgc gagaggacgt aatcggcaag aaggtcgcgg acgagctttc
    14881 ccttcgggag ccaccggagg tgtcccacgt ccgataccgg ttcgtaatcg acgagttcct
    14941 ttccccgcat cagctcgacg tgggcaggct ccccgccgcc ttccgccggc tcgcccagtt
    15001 ctttccggac gaggcagccg aaggcagagt tgtccatgaa tgcctttgcg tcgtgtcgct
    15061 tcccgtcggg tgtcaggacg aagaactcgt gggtcacctc cttcttctcc ttctttgccc
    15121 ctccctcggg gggaaggatg gtgcgggaga gctcggagag ggggtggccc ttgcaggaga
    15181 ggcggaacga cttgtaccac ccgaacggtg cccttttgac ctcgaaaccg atgtcgacga
    15241 ggaggtgctc gagcattttg agggcctcca ctgccgcgtc gggcctcgcg aggtcgctcg
    15301 agaggtgcgc gtacgggtag aggacgatgt tttcgacgga gagctggtcg gccgtcttcg
    15361 atatctctgc cccggcctgc tccacgacgc ctgccatatc gtcctcgtcg ccggactcca
    15421 cggcgcagaa gaccgtcagg gcatcctcgg caaacccctt cagcggctgg tcctcttcag
    15481 ccatgccggt cttctgcttt gcttcaaact cgataaaatc agaatgtatc aggagaagtc
    15541 gcatactttc gctccatccc tctcggattc atccctacct tatctgatgt catccggtat
    15601 aatacccatt cagatatccc ggatattctg gtggtaccgc gagagggtcg cctgccgctg
    15661 gtccatgtac ttggcatcct tcctgaggtt atagggggaa agcgcctttt ccgtggtata
    15721 gaacacgagc tgcccgatcg gcatcccggc gtatatgcgg acaggccggg cgttcacgtt
    15781 gcacatctcc agcgtaatcg acccccggaa ccctgcatcg atccaccccc cggtctggtg
    15841 gagttcgacg ccgagccggg cgatgctgct cttgccttcg atgctcgcga cgatgttgtc
    15901 cgggagaccg atgacctcca gggtctcggc gagcatgaat tggccggggg caagcacgat
    15961 cgagtccgcg accgtttcgc gtgtgccttc cacaacggtc tctgccacgt aggggtcgat
    16021 cacggcgtcc cctgcctcgt accacacgaa atggtttccg aggcgtatat cgagggagtt
    16081 tggctggacg aggccggggt cgaagggctc gacggagata aaacccctcc tgatcctgtc
    16141 cacgatctgc cagtccacga gaatcatggg aaaaaagtgg aacggggaag cgtattaggg
    16201 cttcccccgg cactccccct gcccctcccg gccggcgtcc cgccatgggc acactgttcc
    16261 tgccccgggg gaaaccggca ctgtccgctt cagggtggag taaacgacgt gtccacgccc
    16321 gtgatttcgc tcaggtacac gccggagccc acccaccagc gttcgttgac ggggaggacg
    16381 tacccgatct tcagttcctc cctgttttcc cgtccggggt tgggccagac gaagacgatg
    16441 aaccctcctc ccgatcgggc cgtgtcagcg agtgcacgga tggtttccat gccaaacggg
    16501 tccgcaagcc cgatcaggtt cgtcccgacc gctcccccga ggtgggggtg tgcaaggagc
    16561 gtcccgttgt aatcgtacgc gtacaggtag tgtccctccc catccacgaa catccccgat
    16621 gcgtccggta tcgcggcaaa ggcagcatcg tctccgtgct tccggccgta ttccgcccct
    16681 ctccggacga ggcccgtcat gtttccgatg gccggaggca ttccccgcgg ccccgtatcc
    16741 gcgaggtcgg agagggagag gcctgacccg atccacatgt cactgccggc cgggcagacg
    16801 tacccgatct tcggtacgga gctttccccg tgcgactcgt ttagtgcgcc ggacgccggt
    16861 gccggatcga ggtacgcgat gaacccgccg cctccggatg ccacgtgagc cccgatccgg
    16921 atgacgggaa gaccgcggac gtcggtccgg tcgagcctgt tcgtcccgac ggcctccggc
    16981 tgcgaggggt ccgcaaggag cgtcccgtta tagtcgtagg catagatata aaggtcaccg
    17041 cgggaaaaag gcccggtctt ttgggagaag gtggcaaggg ccgcgtctct cccggaggat
    17101 tctgcgtagt gtgcagcatg cgaaacgaac ccggcaaggt cagccggtgt ccgcacatcg
    17161 ggggctgtac ccgcaggccc ggtcgtgctg cagcccgaac acgacaggac agcgacgagc
    17221 aggaggcagg caagtcccgg taccagcgct ctcttcatgg taatcctgtc agcccccgtc
    17281 cccaataatg atccggttct tctcctgccc ggaccatgtc ccggtagggg gtctcccggt
    17341 accgcaggcg atcactcgtc cgcgtccccg gaatcgtctt cgccgggggg actttccgtg
    17401 cgcacgtcgt gcctgatatg ccactcggac cgccgcatca gcccgtggag ggtcgatgcc
    17461 tcgcgtgcgg tgagccgtgc ccgcccgaat atcctcctca tcatgagcat ggttccctcc
    17521 cgcttgaagg ctgggtggtt gatgagggtc aggtactggt cgatgtgccg gtagaggtgt
    17581 tccatctgtt ccctcccggc gagcaggtac tcgccccggg gaaggccggc aagctcgtac
    17641 gcgatgatgg caacggcatg cgagaggttc aggatggggt agtccggcga cgtcgggatc
    17701 gtgcacacga tgtcggaccg ccgcatctcc tcgttgttca acccccagtt ctcccgcccg
    17761 aagaggatgg agacggtccc ggcaacgtcc ccgatcatct cccggagctc cctgggggaa
    17821 cagtagggca tcctcatcgg gtggcagatc gtctttccga cctcgccggt ggttgcaacg
    17881 gtgatgtcgc tttcagaaaa gacttcttcg agggaacaga cccgggctgc cttcaggacg
    17941 tcggatgcgt gcgcagcccg ggcgagggcg tcgtccccga gcgggcaggg gtccacgagc
    18001 acgagccggg agaacccgaa gttcttgatt gcccgggctg caaacccgac gtttccctcg
    18061 tagagcggct caacgaggac aaaacggatc tcaggcattc ggatcggttc ctccgggaaa
    18121 atccggcagc gcttccaatg gttccggcca acggggggaa caggcccgcc cgcctttttt
    18181 tcagatcacg gccctgaccg ttgcccgcag ggcatcgatc cccttctcgt agacggcgtt
    18241 gccgaccacg atggtatcgg cgtactgtgc catctcggcg gccttttcgg gcgaatcgat
    18301 accgccgccg tagtagagga ccgaggattc gagcgccccg gacaccgccc tgacgaccgc
    18361 cgggtcaccg tacatccccg agtactcgat gtacacgatg gggaagtgga agtagcggtc
    18421 cgcgaccgtc gcgaacgccg cggcttcctt cggcgagagg gcgcagttgg cggccgtgac
    18481 cttccccacg gaagagttgg ggttgaggac gatgtaggct tccgggacga cgcgttccca
    18541 gtcgatctcc tgctgcagca cccactgggt gtgcttcccc acgatccatt cgacgttctt
    18601 cgtgttcagg acactcggga cgaagaggag gtcggcaccc tcgctgatga ccgcctcggg
    18661 accggccggt tcgacgacga ggggcaggcc gtacgcggcg acctgtcgca ggagttcctg
    18721 catattcttc ctggtcacgt tcagcgtccc cgagagcatc agggcatcgg tcccgctggt
    18781 gaccaccccc tgtatctgct cgggtgtcag ctgcctgtcg gggtcaagct tggtcacgtg
    18841 ggtccagctc ttccagttga tatgcatgga cgggctcctt gttagatcac tatgatgtct
    18901 tcccctgacc ttttcttctt tgtgagggga gcagctttcc ggagtgcggc aatcttctgg
    18961 cgggggaggc cggacctgac cgaaatcagc gattcgtcga gcccgtgcag ggtctccctg
    19021 tcaaagaccc ccgcagagag gagctggctg tagacctggg gcgtcatccc gggcacggag
    19081 aggaggtctt ccctgccccg gcggaacttc gcggcagtca ctttctccgg cacgggtttt
    19141 cccaggtggc gtgcaaccgt ttccacgtgc cggaagaccg tgtccgggga tatcccggtc
    19201 ttttccgcga tggcaagcgg gtggatcgtg aggagtgatt cgggtgtgac gaacccggca
    19261 ccgaggtact ttttgaggct tgccggcggt atcccgatcg tcctgagggt acgctcgccg
    19321 acctcgcggc gtgccccggc ctggagggcg tcgatctcct tctgcgagag ccccgcctcc
    19381 ctgagaacgg ccgggtcggc cttcccgagg tcgtctatcc cgttgatgcc ggcctgggcg
    19441 agtttcttca cgatggtgcc cgggctcctg cctttccggg gggcaatgcg ggaacggacg
    19501 aacttccggc agtcggaccg gcgccggagg aggtcgaggg cttcttccgc ttccttccgg
    19561 atttgccggg cacgttcggg ggtgatgccg gggatttccg cgagtttttc gtccggcgtc
    19621 ccgatgatgt cctgcaccga gtagatccgg gccgcgacca tcttttccgc gagatccgca
    19681 cctgccgagg ggaggagggc gagcgtctcg cgcagcgacg cgatctggtg gcagaggggg
    19741 cacccgatct cccacggccg cgaccctttg cgcacgaggc ggacgtggta gagcccgtgt
    19801 tccgggcacg tcctgtccgt ccggagcgcg tacccccaca tcgttgccgg gagcccgatg
    19861 ttgaaggtgc attcagggta atgcgtgcac ccgatgaact gggtctggtt ccggacgtgg
    19921 tggatccgaa ggtcgtgacc gcagaccggg cacggtccca gcctcagttc ctctgcggtc
    19981 tgttcccgga tctcgtcccc gatctcctgc tcgtgcgcct cgagctggtc aaagacctgg
    20041 tgcagcattc cccgggactc ctggaccacg tcgtcgctct tccgggcccg ttccttgatc
    20101 tgctgcatgt ggctctcgag cgtctgggtc atctccgggc gcgtgatcgt gtcggcatgg
    20161 ttctcgaggc tctcgatcac cgccctcccg acgagtgtgg ggcggagggg gttgccctcg
    20221 acgtacttcc gcgagacgag tttctggatc acctcgtgcc gcgtgctctt cgtgccaagg
    20281 ccgagctcct ccatcctctg gatgagcctg ctctgggtga accgcggcgg gggctgggtc
    20341 tccttctcct ccatccgcac ctcgcggagc gggaggactt ccccttcctt cagcccgggc
    20401 aggacgtact cggttgccgc gctgtagggg tacaccttcc gccaccccgg ctcgaggatc
    20461 tggcctcccg tgacggtgta gggctcccct cccgccgaga gcatcacttt catcgtgcgc
    20521 cagcgtgcat cgggcgagag cgttgcgagg aaccgccgga cgaccagttc gtacagcttc
    20581 cacctctcct ccccgagttc ctcccgcccg gccggcccgg tcgggtggat gggggggtgg
    20641 tcggtgctca ccttctgtcc gcgggtgggc acgggtcttt ggtttgccat cacccattcc
    20701 acgtcgggcc ggaaaaccgt gggccggatc gcggagagga cggatccaag gtcgagcgtt
    20761 gcgggataga cggtgttgtc ggtcctcggg taggagatgt acccgttcat gtagagttcc
    20821 tcggcaatgc gcatcgcgtt tgccgcggaa tacccgaggc gggcagcggc aacgatgaac
    20881 gaggtcgtat cgaagggaga gggggcacgg tcgaccttcg tcccctccac gacgctcgtc
    20941 acgacgaggg gcgggacact cctctccttt gcggcgaggg cctcatcgaa agtatggaac
    21001 cgcgatgtcg tgtgccgggc ctcgatatcc tcgcccccct tgcccgtgag gaggcgcagc
    21061 tgccagtatt tctccggctt gaaagcctcg atctcccgtt cccggtcgac aatcatggcg
    21121 agggtcgggc tctgcaccct cccgaccgag aggatgtttg ctcccccccg ttttgccgcg
    21181 agcgagagga accgcgtcaa agacgctccc cacatcaggt cgatgacctg gcgggcctcg
    21241 cctgccgatg cgagggcaaa gtcgatttcc gtcggcgatg cgaacgcgtg ccggatctcg
    21301 ccgggcgtga tcgccgagaa cctgaccctg tcgaccggga cggacgggtt gacggcccgg
    21361 acgagttcgt aggcctcctt cccgatgagt tccccctccg tgtcgaaatc ggtcgcgatc
    21421 gtcaccctcg ttgccttctt tgcgagtttc tggaggaggg cgacgatctt tttctctgtc
    21481 gggaccttga tcgtcggggc gtcgatgagg ctccggggcg tcttggactc gctcctccag
    21541 ttcgagtagc cttccacgaa atcgacctcg acgacgtgtc cccggaggcc gacgaccgtg
    21601 gtcccgttga agctgtaact ggatatcccg ccgtctttta attcccggac attcttttcc
    21661 ccggcgagga tggatgcaat cctccgcgcg gagatgttct tttcggcaac gatgaggtgc
    21721 atggacggga tcacgcaccc tctccgagga ggctggcgag cacccggttg acgtctgcag
    21781 gctttgcgca tccccgtgtc ttcctcatga cctgcccgac gaggaaattg agggcttctt
    21841 tcctgccgtt ccggtaatcc tcgacggcac gcgggttctc tgccagcgcc tcgcgggcag
    21901 cttttgtcac cgggtcgtca cccccggcac tgtcggcagg gagtgcacgc aggccgagcc
    21961 gctcagcaca cgcttccggc gactcgcatg tccccttctc cttcagctcg tcgaggagga
    22021 cacgcaggac gtcgacgccg ttccggtccg tgatcacccg tgcccggacg agggagagga
    22081 gcccggaaaa gacgtccggg ggaacggacg agatcgacat gtcccggtaa ttgagctccc
    22141 cgaggagcgt gtccgccacc cacgtggcag cgagtgccgg gtcggtcccg gcgaccttct
    22201 cgtagaactc cgcgaggcgg aggtcccctg tcagcgtccg ggcatggatg agggataagc
    22261 cgtactggtc catgaaccgc tggcggcggg cgtccgggag ctcgggcagg acaatcccgt
    22321 cgacccagtc cgcgaccctc agggggcaga ggtccggttc ggggaagtac cggtagtcct
    22381 gttccatctc cttgctccgt gccgacgtgg tgaccccccg cgcctcgacg aagtggcggg
    22441 tctcgcgcac gatcttctgg ccgcggcgga gcgcattctt ctggcgggtc acctcgaagg
    22501 tgagggcttt ttcgacgccc ttgtacgacg tgatgttctt gatctccacg cgttcgctcc
    22561 cctcgatcga gatgttggca tcgacgcgga gcgacccctc cttctcgctg tcaaagacac
    22621 cgaggtactc gagcgtcgca cgcagcttgt tgaggaacct gcgggcttct ctgggggacc
    22681 ggaggtcggg ctcggtgacg atctcgatca ggggaatccc ggcacggtta tagtccacga
    22741 gggaataccg cggccggtcc gtccctccct tgtgcacgag gcgccccggg tcctcctcca
    22801 tgtggaccct cgtgatgcgg accctctttt ccccctcgtc gccctcgatg tccaggtacc
    22861 cggacacggc gaggggcttg tcgtactggg ttatctggaa ccccttgttc aggtccgggt
    22921 aaaagtagtt cttccgggca aagaccgact cctccggcac ggtgcagtgg agggcctttg
    22981 caacccggag tgcgtattcc acggccttcc ggttcaggac ggggagcgag ccgggcaggc
    23041 cgaggcagac agggcagacg tgcgtgttcg ggccatcggt gcggtagtct gtcgagcacc
    23101 cgcagaagag cttggtcttc gtgtcgagct ggcagtggat ctcgagcccc acgatgacgt
    23161 tcatgggttc gccccctgct cgtacgcgta ggcgacatcg atgacccgct cgtcctccat
    23221 ccaccgtccc atgatctgca ggccgacggg gagaccttcg accttcccgc acggaacgga
    23281 gattgccgga acaccggcga ggtttgccgg gacggtgagg atgtcggaga ggtacatcgc
    23341 gagggggtcg ctcttttccc cgaaccggaa cgccacggtc ggcatggtcg gcccggcgat
    23401 gacgtcgact tccgcaaaga ggcggccaaa gtcctcccgc acgtttctcc gggcggcctg
    23461 tgccttcgcg tagtacttcc cgtagtaccc ggaggagagg gcaaacgtcc cgatcatgat
    23521 cctccggcgg acttcgaggc cgaaaccctc gcggcgccgt tcctggaacg cctcgtgcca
    23581 tggtttccgg acgtctgccg ggggaccgta ccggacaccg tcgtaccggg cgaggttgga
    23641 actcgcctcg ctcatgcacg tcacgtagta ggctgcaagc gcgtacgcca tcgacggcat
    23701 cctgcaggtg atgatctctg cacccttccg ctcgaggagg gagattgcgt cccagacaac
    23761 ggacgcaacg cgggggtcga ctccctcgcc gaagaactcc tcggggacac cgatccgcgt
    23821 ccccctgatc tccatcgagg gtgtgtggga atagggtgcg tcaagggacg tcgagtcttt
    23881 cgggtcgtgc ccggcaatga cgctcatcag gaggtttgcg tgcgcaacgt ccgctgccat
    23941 cggcccgatc tgctcgaggg aattggcata ggcgacgagc ccgtaccggg atacccgccc
    24001 gtaggtgggc ttgagcccga cgatcccgca gaatgccgca gggcagcgga tcgaccctcc
    24061 ggtatccgtc ccgagcgcga gcgggacgag ccctgcagcg actgccgcgg cgctcccgcc
    24121 cgatgacccg cccgggaccc gtgtctcatc ccgggggttc ttcgtcgggc cgaacgccga
    24181 gttctccgtc gtgctcccca tgccgaactc gtccatgttg gtcttgccga cgatggcagc
    24241 cccctccttt ttgaggaggg agacgaccgt tgcatcgtag ggggggacgt agcccgagag
    24301 gatgcgggag ccgcacgtgg tctcgatccc tgccgtcgag atgttatcct tgatcgcgac
    24361 cgggatgcca cggagccggc cctccccgta ccgggccggg gagaccgtcc ggaggaacgc
    24421 gttgtaccgg tcgtccgggg aaaaggtgag catcccttcg gccatcacat cacccggggt
    24481 gccctgaaga acccgtcttc ggtctccttt gcgttcgaga ggacgtcttg tggcgaaagg
    24541 gaggggacga cctcgtcctc gcgcaagacg ttgactgcgg ctcccccgtc cttttcctcc
    24601 ccggtgacct ggtcaaggat gtcgaagtat tcgaggatcc tgttgaaact cgccgtgaac
    24661 tcttcgagct ccccgcggag tatcgcgata tcggcaagca tcccgatatg ttccacgtct
    24721 ttttctgtga tcatcccttc cccatccctc cgggagtgtc ccgatgcgta tgagaataag
    24781 taccctcccc tctgcctttt ataaccattg tgccgggata ccgggcgggg aggggacacg
    24841 tgcagccggg ggaaacgttt cagcctgccc ggaatttttc caatgctcac gtatttttga
    24901 aaaataggtc tcctgattcc cttccctgca cagcccgctc atccgggtac ccgcgcgagg
    24961 tattctccta ccgtgcggca gcccctcttc ctcgcgagcc tctgcagttc ccgccagatc
    25021 ccgctcccgt actgcatggc cttcttctcc ttccacgcaa tgccgggtgg gaggaactct
    25081 gccgcaacct tccggagggc acgtttcctg atgcccccgg agaccttctc ccccgcggga
    25141 atggcccgtg ccgcggcgat gacccgtgcg tccaggtacg ggtacgagat gagcacgccc
    25201 tctccggtgg cgaccgcctg gtcccgtgcg atctgccccg gcaggcgtgc gaaatcggcc
    25261 gcgaggagtg catcggtgtc cctgtcggcc aggtaccggc tgtatccccc gaagagctcg
    25321 tctgccccct ggccggagag gacgcggtca tgccctgcgt cccgtgcgga ccgcgcgatg
    25381 aagtgccagc acagcgcaat cgagaggtcg agggggtttt tctccgggat gagggagagc
    25441 accccgggta ccgcgtcttc gacgtcagca ggcgtcacgg tgacctctgt acagtcaagg
    25501 ccgagctccc gggcggcctg cctgcctccc tcgaggtcaa aacttccctc catccccgcc
    25561 acgatgcagg gccggcgggc gatcgcggca acgagggccg agtcgacgcc gcctgagagg
    25621 gcaacgaccc cccggtcgct ccggagctgg acagcagtca cgatggcctc tgcaagaccg
    25681 gtcttccgga accgggggca gaccttcccg atgacgcggt ccccgtcgag gatcgtcccg
    25741 ggaggaatgg gccccggcac gatgccgagt gcgtcccgtg cccggtaccc gtcccacgaa
    25801 agatagaact caccgccaaa cgacgaggcg gcgagggggt cctgcaggag gcgggcacgg
    25861 acctctccgg gcgggaggac cactccgtcc tcctcgaccc agccggccgg tccggggctg
    25921 tcgtccctca tttacggagg cgctttgaac gggggacgta ctcatccggg cgccggagga
    25981 ggaaaaaggc gacaaccact gccccgatca tgacaagccc gatgaccgtc catgcaggca
    26041 ggggcacgga aaacgagtcc ccgacgacgg aataaccgtg cgcaggagcc ggctgcgtga
    26101 aggaggcctg cgtgaagggg gtctgcgtag gctggggttc gacgatatcg ggggcaccgg
    26161 gtggcacgac cgcagagaca cccgcgaccg ccgcgttcag ggcgaggacg agcagggcaa
    26221 gggacaggac ggcccttccc tgtcgcccgg cctgcaggac aaaagaccct ggattgcgca
    26281 tatcagatca tcattctttt tgtgcacagg agtataaaat ggaaatgcca ggtgtcctga
    26341 tggaaaacag gggtttgaaa ggagaagagg ggatttctgc gacggtgagc gtgatcctga
    26401 tggtcgtcct cgtcatcggg attgcactcg tcctctggtc ggttttcatg gggtatccat
    26461 ccatcctcca ccataccgtg tacatcgcga gcgaggccaa agcagaagag atcgtccagc
    26521 ccggcgggct cccgatggag gtcgttgcct tcaccatcag ggaagccgaa ccgttccatt
    26581 tcgctgggca gaaccccccg gtcgccggca aggaggtgct gatcaaggtg gtcacgccgg
    26641 acgggcgtac gatctacccg acgcccttca tctccggggg aaacctcgag ggaaagacgc
    26701 tctacatctt cccgaactcg accgggtttt cgtcctactg cgactatatc gtctccgata
    26761 cggcaccggc cgggcggctc aagccgtttg tgaccgggac atgggtgatc cagctcatcg
    26821 acccggaggc aaacctcctc atctcgagcg atgacagggc caggatcacg aagggaacga
    26881 ccgcctatcc cgttgcgggc ggaataccgg ggaacggggt ctacaggacg gactgcacac
    26941 cgcttgcctc cagcatcaac gggaaccccg tgcggggcaa tacgggagcc cccatgaaca
    27001 tgagctacct ctcgttcgat ggagacgact ggatcgcgta cgccgacgac cccacgctca
    27061 cattcacggg tgacctcacc atctcgatct ggttaaaacc gcaggatgtt acgagctgga
    27121 agcaggtgat cggcaagggg ctccagatca gtacaaacaa ggaagacaag aactacgacc
    27181 tctacctcat caatgacaag gtttacttcg agtgggacga cagggtgacc gggactcatt
    27241 accatgtcat gaccaatgca cctgccgtga ccggcggttc gtggcagtac gtaaacctga
    27301 tcgtggatgg gggaaagccg aaaatttacg taaacggctt gtcgcagcct ttcacctatt
    27361 accagtcaaa cgtgccgggc actaacccga tcacgaaccc gtcgcaaatc ccggaagtcc
    27421 ggctcaagga caacgaccac ccgatgacga tgggaaaaca ggcatcaacc agttacccct
    27481 tctactacaa gggctcgatc ggctccttcg ccctctataa caggggctta acggatgccg
    27541 agatacagga gaactaccag acgtacagag cctgaaaacc cctcccccct ttcattttcc
    27601 ggaagtactt tcagaaagca cccgcccgac cggcaaatat tattccccat cccgccgatc
    27661 tttgggcaca ggagaggtat gtcccggttc gtcaggggag acgtggtcct cgtgccactc
    27721 cggatagggg gtgccggccc ggagaaggtg cgccctgccc ttgtcgttgg cggggaggga
    27781 gagaggctcc gggtcatccc cgtctcgtgc actccttccc gcgacacgcc gtcagtcccc
    27841 ctcgccccca tggacttttg caggggggga ctcgacatcg tcagggagag ttacctcctc
    27901 ccggcacatg cggcatgggt ctttcacaaa gctgtcatcg ggaagaaggg acgggtctcg
    27961 caggagttcc tgtcccggtt tgtgggggtc atgtgaagga cggggtggcc cggtaacctg
    28021 ccacggggaa tcacgccacc cggccttctg cacgttttcc acgcggtgca gtgcctttct
    28081 ggtcaccggt gacggggatc acccggagaa agatcactac ccggacaacc gatcccggca
    28141 tttccacggg gtttaagagg cccatccccg atatactgat ccagcatgcg gaccaaccgt
    28201 caccagtact tcctcgacct tgcactccgg tgcgcccacc agggcacgtg cctgcgccgc
    28261 aacttcgggg cgatcatcgt ggacgagttc cacaccatcg tctcgacggg atacacgggg
    28321 gcaccgcgga aacagatgga ctgcacggag ctcgggcgct gctggagaaa ggatcacaac
    28381 atcccgtccg ggtcgcacta cgagcggtgc cggagcgtcc acgccgagat gaacgccctc
    28441 ctgcaggcag gaaagctcgc ccgcaactgc acgctctacc tcgccgggtt cgaggtcgat
    28501 accggtgaac tgacccggat ctggccctgt ttcctctgct ccaagatgat cgtgaacagc
    28561 gggatcagaa cggtcatcat gcggaccggc cccgaaacgt tccaggagat ggacccgatg
    28621 gttctctacc agatgcggag cagggaggca ctcggcgacg gcgggccggc gtaacaaccc
    28681 ctcctgcccc gggatggatc cccgccgggg gcgcggnnnn nnnnnnnnnn nnnnnnnnnn
    28741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    28801 nnnnnnnnnn nnnnnntcac tccctccagc cgattgcggc tttccagccg gtcactcctt
    28861 ccgtcgtgaa aactgcccgg tgggacgcgc cctcgaagcg gtacgagacc tcgccctcat
    28921 cgcgggcctg gagagccgcg agggctgccg gatcgcctgc aagggaaaat gtcctgtccg
    28981 gaagcgaatc gagcacggtg ttcccgctgc tgtcgaggat aaagaaatag tatccgtccg
    29041 ggaggggcag ggaccgggca agtgcatccc cgaggctgtc gcagtacacc gatgtcccga
    29101 ggatctgcgt gacttgtccg cccgccgtga cggggacggc gatgatcgcc gtgttcttcc
    29161 cggtcgttct ggacaggacg accgtcccta tcgaggtctt tcctccaagg acgaccggga
    29221 agtagggacg gtcgcggatg tttgcactcg tcaggttatc cacggtcgtg tagtacgagc
    29281 cgtccgggcg ggcataccag aaccgggctt ccggatggtc cgactcgagg cgcacgagga
    29341 ggggccggac cctctcccag tctccggacc ggacgtccga cgtgagggcg agcgcttcga
    29401 gggcagcaga tatcccgtgc atgcgggtgc cgacgaggga cgagagggcg gagagcaggg
    29461 tttttgccgg gacaccgccc tgtgcagcag tcgcgggagt ctctcctttg ccctctcccg
    29521 cccccgtgag ccgggcatac gtcccgtcgg ccttcatggc atcgaggacc tcctggaact
    29581 tctttgcggt tgcggggctc gtcgtgttct ggaacgcgag gtacaggtcc accctgtgga
    29641 gggtatagac ggggatgacc gtcccctccg caacccctgt ttctgccatg attccgggtg
    29701 ctgccgcgga ggagccgagc cagagggaga ccgaccggtt ctgcagtgcc gccaggcact
    29761 ctgcatcggt cgggtacgtt ttcacatcgg tgaaccggtt cgcgaggagg aacgtgtgcc
    29821 gggcgtctcc ctccacgacg gcgatcgtgc cggcagcccg ggctgcttcg aggctctcga
    29881 ggcggatacc cgaatcgctc ctcgcataga gcacgtattc aaacgtcccg atcggcccgg
    29941 cccagaggaa gagcggttcc cgatcaggcg tccgggcggt ggggaagagg gcggcaccgg
    30001 gtgtccggag tgctttttcg taggacgtgt tccagggatg gacctcgatg cgggcgctgc
    30061 acccgctgcg ccgcaccatt tcccggacga cggcaacgga tgttcccccg ggcgtccctg
    30121 cactgtccac ggtggaatac gggtatatct cctcggtcag gaggaggagt tctccctccg
    30181 ggcacccgga taccaccttc tgccccggag tctgctgttc catgcatccc ggggccagca
    30241 cgaaaatgcc gagcagtgcg caggcaacca ggggaatggc aagtccacaa agagatcgca
    30301 tgcttatcct cattcctttg tcccgttctt tttttcgggg agaaaaaaag ggttacggtt
    30361 ttttttagtg tgtcactcca cgcccggacc atcctgcaat cagccggggg ccggtgcctc
    30421 ccgcagaaca gatggcattc ccgctggctt tttccatggt ctccacggag agagcgggta
    30481 cccccaagcc cggcacag
//
LOCUS       DAOOJU010000021        29261 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1687_length_29261_cov_15.840546, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000021 DAOOJU010000000
VERSION     DAOOJU010000021.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 29261)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 29261)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29261
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1687_length_29261_cov_15.840546"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(242..427)
                     /locus_tag="PK679_06355"
     CDS             complement(242..427)
                     /locus_tag="PK679_06355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55612.1"
                     /translation="MAQLIIEPKKGKDGQIEYIVNYHDMKSDNSFTITTTSDQNEALE
                     KLKNTLEGEVQAMMQKK"
     gene            542..613
                     /locus_tag="PK679_06360"
     tRNA            542..613
                     /locus_tag="PK679_06360"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:574..576,aa:Ala,seq:tgc)
     gene            complement(857..1867)
                     /locus_tag="PK679_06365"
     CDS             complement(857..1867)
                     /locus_tag="PK679_06365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription initiation factor IIB"
                     /protein_id="HPC55613.1"
                     /translation="MQEVEKLKVLQKEREALKKRLKDRVKEHEKKAEDHTETVCPECG
                     SRQLVHDYERAELVCQNCGLVIDDDFIDRGPEWRAFDHDQRMKRSRVGAPMTFTIHDK
                     GLSTMIDWRNRDSYGRAISSKNRAQLYRLRKWQRRIRVSNATERNLAFALSELDRMAS
                     ALGLPRNVRETAAVVYRDAVDKNLIRGRSIEGVAAAALYAACRQCSVPRTLDEIAEVS
                     RVSRKEIGRTYRFISRELGLKLLPTSPIDYVPRFCSGLNLKGEVQSRAVEILRQAGER
                     ELTSGRGPTGVAAAAIYISSILGGERRTQREVAEVAGVTEVTIRNRYKELAEKLDIEI
                     IL"
     gene            complement(1885..2109)
                     /locus_tag="PK679_06370"
     CDS             complement(1885..2109)
                     /locus_tag="PK679_06370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gar1/Naf1 family protein"
                     /protein_id="HPC55614.1"
                     /translation="MKSIGLAVHAIGARILVVRCDAAQLPRLYSEVIDRRMKPVGRVV
                     DVFGNVSSPLAAVLCKGPCAVTAGEKLFIR"
     gene            complement(2215..2865)
                     /locus_tag="PK679_06375"
     CDS             complement(2215..2865)
                     /locus_tag="PK679_06375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase
                     domain-containing protein"
                     /protein_id="HPC55615.1"
                     /translation="MYDLHTHTVLTDGDMLPAELVRRLAFLGYTHVGITDHADATNVE
                     ELISATKKLVPLAKDYGVTLLPGVELTHVPPGMIPKMAREAKKCGAEIVVVHGETVLE
                     PVAPGTNLAACGCRDVDVLAHPGFLTEEEAALACSNDVAIELTSRCGHNRTNGHVAAV
                     ALESGCVLVIDSDAHSPGDLMDARARKVVGMGAGLSSAQCERILSFNIEEFLFHKK"
     gene            complement(2870..3142)
                     /locus_tag="PK679_06380"
     CDS             complement(2870..3142)
                     /locus_tag="PK679_06380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle subunit SRP19/SEC65
                     family protein"
                     /protein_id="HPC55616.1"
                     /translation="MKGERIIYPCYFNSALKRGQGRRVALSGAVSDPTLADLERAAKR
                     SGLVFRSEQKHFPARWWLKEGRIVVTWSESKEKLLRKIASHLAQGK"
     gene            3199..3846
                     /gene="hypB"
                     /locus_tag="PK679_06385"
     CDS             3199..3846
                     /gene="hypB"
                     /locus_tag="PK679_06385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HPC55617.1"
                     /translation="MHHIDVRIEKDVYDINRRIAEENARTLRKHNVRAFDLLGAIGSG
                     KTALIEKVVPLLQERGLRPGAIAGDVYGDDDYQRIRALGIPAVNANTGKECHLDAHLV
                     EHALESMDLDSIDILFIENVGNMVCPTDFPLGAEKRCVIVSSTEGDDVVNKHPMMFRG
                     CDIGVINKVDLAPLVGADLDRMENDMRRYHPGMKVFRTNLRKGEGVVPFLDALLG"
     gene            3951..4328
                     /locus_tag="PK679_06390"
     CDS             3951..4328
                     /locus_tag="PK679_06390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8e"
                     /protein_id="HPC55618.1"
                     /translation="MLWQGRSVRKPTGGRYRLRLVKRRREIGSAPTDSHIGKDRRAIV
                     RITGGNIKVRTMRAEYANVADPDSGTVRRARIETVEENIANPNYVRRNLLTKGAVIRT
                     EAGRARIISRPGQEGVINAVLLK"
     gene            4772..5233
                     /locus_tag="PK679_06395"
     CDS             4772..5233
                     /locus_tag="PK679_06395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2240 family protein"
                     /protein_id="HPC55619.1"
                     /translation="MSLSLTIAAPFRHSHRSELKKNEIVYYLAFKQHWMNIEQANQVI
                     SRAIEEGLIGIEGDMIRPLFDVSRVEIPLGFKPGASVFQRSDPVDDLVFRISERTGIP
                     KGSVVSEINSIIQDVFQGNLTSEAAAVILAKRHGVEFQDLLPALREHVLTS"
     gene            complement(5292..5696)
                     /locus_tag="PK679_06400"
     CDS             complement(5292..5696)
                     /locus_tag="PK679_06400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6e"
                     /protein_id="HPC55620.1"
                     /translation="MAEFKVVLSDQKSGRSFKVDVGGGAAGALIGKRIGDEVDAGIFG
                     LQGYRMVITGGSDRNGTPARRNLPFAGRRKILLSGGAGFKPRREGQRRRKTIRGNEIT
                     ADFVQINARIVQYGEKSLDELFAKPAAEGKTE"
     gene            complement(5859..7634)
                     /gene="infB"
                     /locus_tag="PK679_06405"
     CDS             complement(5859..7634)
                     /gene="infB"
                     /locus_tag="PK679_06405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HPC55621.1"
                     /translation="MSEKPRIRTPIVCVLGHVDHGKTSLLDRIRGSSVVSMEDGAITQ
                     HIGATIVPIEAIRKMSGSMEKVPLNVPGLLFIDTPGHHAFTTLRARGGALADMAVLVV
                     DINQGFQPQTLEALQILRTYKTPFVVAATKIDRIHGWKVNRDEPFLASFGRQNERVKE
                     LLETKVYEVVGKLSELGFSAERFDRVSDFQRNLAIVPVSAHTGEGIPELLMVMIGLAQ
                     RYMEKALSLSIDGPGMGTILEVKEEKGLGTTLDVILYDGTLSVGDEIAVAKQDGIIVT
                     KVRALLQPRPLQEILVEERFCRVRSVTAAAGIKVSAPNLEGAIAGSPVHVVRGDADSV
                     MEKIRREMETINVHLSPEGLIIKADTIGALEALCKELEEKEIGVMRAEVGSVSRHDLV
                     EAMTIKNPYYRVLIAFSTPLLPDAADMVREPGFPVRVFEGRVIYKLVDDYVQWRDDLK
                     RRIEQQKFEQIIFPAKIRILPHCIFRQSNPAVVGVRVLGGTLRTDVNLIQRDGRKVGH
                     VKSMQLNQENIREAQTGAEVAISIEGATVGRQLDVDDELYVDVPEKHVKVLEKEMLSH
                     LPIHTQEVLAEFTAMRRKENPFWGK"
     gene            complement(7631..7771)
                     /locus_tag="PK679_06410"
     CDS             complement(7631..7771)
                     /locus_tag="PK679_06410"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55622.1"
                     /translation="MVLHYIARYQSGAVSGKRVSPLFPVSPSHNQTSGLSIPSCTPEE
                     EK"
     gene            7858..7930
                     /locus_tag="PK679_06415"
     tRNA            7858..7930
                     /locus_tag="PK679_06415"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7892..7894,aa:His,seq:gtg)
     gene            8443..9315
                     /locus_tag="PK679_06420"
     CDS             8443..9315
                     /locus_tag="PK679_06420"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC55623.1"
                     /translation="MEKSVLKYLILCAVVALIAPASADSATEASKDQGIYRFHSNVDG
                     AEVYLNGQLIGSIQDYILDVPVSASGPFYRNYTLMKEGYKPYSGIINSIPKKGQVIHI
                     YVVMSAQAMVEYGTVHLMVTPADAEVTWDGSPAGKVPPSGILVLYNVLPGSHSLVIGK
                     EGYETYYGSLYVPPNEVVKFPVTLTPIQAGALSVESVPAGAAVSVDGQYRGVTPLVIR
                     DLPAGSHTVSLAGEGYQEYVSSVEVTGGATATVSVTLLPATTSVPAGRSPVSPVLIVS
                     GLGVALVLAGRKML"
     gene            9336..9806
                     /gene="msrB"
                     /locus_tag="PK679_06425"
     CDS             9336..9806
                     /gene="msrB"
                     /locus_tag="PK679_06425"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HPC55624.1"
                     /translation="MLSEGACDNTVILYDAATGTREPKSRICRSPEEWRALLAPEVYT
                     VTRDKGTEPPFSSPLTRCNAEGVYRCACCGTDLFMSGKKFNSGTGWPSFRAPVDPCNV
                     HRERDTSLGLERIEVLCARCNAHLGHVFFDGPPPEGTRYCINGLALSFHPGSRK"
     gene            9929..10726
                     /locus_tag="PK679_06430"
     CDS             9929..10726
                     /locus_tag="PK679_06430"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC55625.1"
                     /translation="MKESDGTILSADDSEFLGELSEYLEVLGNSTRLRIIRFLEKEAM
                     DARTLSRRTGISYENTKKHLEKLLGAGLVTRVPGLGRETSRGIHPAWNYLPVPGILER
                     IQRDLGVIASVQDKRGQDALQQRIESVRREVGKALGTAGWMLLVIGGEWDGKTICLQS
                     PRTELGRGREEGISGEGGITRIAFPPSYRSVTRLEKPHAIIRTGRGECTIEDAGSRGG
                     TFINDQKIIPHDQVPLKDGDRIMLSRGDFPVTLLALKSDTVGERPHE"
     gene            10719..12563
                     /locus_tag="PK679_06435"
     CDS             10719..12563
                     /locus_tag="PK679_06435"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: protein motif:HMM:NF019334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase"
                     /protein_id="HPC55626.1"
                     /translation="MSEGSSSFLRFTLIVFVLVLVSAAACHADNNKAIKIPQSLTNKS
                     IKEDLFAFLKQGAESAQSILRPTMTMPQITPFPTVTAPGKGAIPTRPLTGQQTVTPPA
                     TLRPITTETSLPITPTATTPAPAATQFTQQTTISPGGTTQPSAGTVSWSGIGILAGLF
                     LSACTGYVYLVHNSIRRRDSMPVAWWVRYSRILAGFHAALAVVFVVMVLGIVLPFLDT
                     ARETPVDPLISLSSGAIAGFAAISSLVMSYFTLSGHLPRRVGTVHAAVALAGTLLIPA
                     LAFLQGSAGPDPLRIVPFLSGLVLAVVQAREGGLRFGVPPRNAPLPDTLLFEDENLPG
                     PGPDFPAALSSRYYGARYIHHGGIAHVFSAYRRSDGVAVAVKIPIRTDEQTGKSFLRE
                     MKVWEGLVHPGIVRIYSANILPVPYVEMEYLPRSLADTPVPISPAASLGIIRKIGEAL
                     LYAHDRGVIHRDLKPENILVTSGGEPRIADWGLARDEKGTFQTTLHGFSLSHAAPEQL
                     DPGRFGTTTQQTDIYQLGIIWYWLVCGTQPFSAGSIAEATRERLEGEVVPPSARVPGI
                     ELLDPVILRCLARNPSERYRDMREFLKDILDLETRLGGKNGGAGTGNA"
     gene            12605..13816
                     /locus_tag="PK679_06440"
     CDS             12605..13816
                     /locus_tag="PK679_06440"
                     /inference="COORDINATES: protein motif:HMM:NF015948.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HPC55627.1"
                     /translation="MNKPGLAGEGIPVAVVACPDYMPQNVSRALRRALDLVGGLPAFV
                     PPGSRVLVKPNLLQAVPPERAVCTHPVVTGEVVRSLTDEGCSVTVADSPGGGTRYTER
                     NMERVYRVCGYAHLPEETGCSLNHDCRYREITVPGGSVCTRFPLIYPYFQADSIVSVS
                     KAKTHVLTLMTGATKNLFGLLPGLEKPLFHSRFPDPAVFSDMLLDLLLVVRPALHIVD
                     AIVAMEGDGPMSGSPRPLGAIVVSPSALAADIVLCRLMGIDPARVPYLARAAARGLVA
                     LDGSGIDLRGDPVSMLRGEDFRIPGTYASGKSGFSIPLVFRVVHRLGKVYQLRPVVDG
                     SRCSGCGRCTVACPSNAAALVHGRASIDPRKCIRCYCCHEMCEQGAIRLERGVVGALI
                     HAIAGEKRHEE"
     gene            14132..14269
                     /locus_tag="PK679_06445"
     CDS             14132..14269
                     /locus_tag="PK679_06445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55628.1"
                     /translation="MTRKMYPPHIPRLLEKSRKRPDLARIITRARLAYRNAISRNAWP
                     R"
     gene            14374..14529
                     /locus_tag="PK679_06450"
     CDS             14374..14529
                     /locus_tag="PK679_06450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55629.1"
                     /translation="MCTVGGPVDLEVPPDRVKGKNYRCRECGEKFRGVGKHPVCPSCQ
                     SEDVEEV"
     gene            complement(14656..18210)
                     /locus_tag="PK679_06455"
     CDS             complement(14656..18210)
                     /locus_tag="PK679_06455"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55630.1"
                     /translation="MISVLLVDDEPPLLDITQIFLERDGKMKVTLSESAKDALEKLAV
                     RKFDIIVADYEMPQMTGLDLLKAVKNLGYDIPFIIFTGRGREFVAIEALNLGASFYLQ
                     KGGDPKSQFAELRNVIVQAVQKKRAEEEIHLNQMRLQAVIELYQMSDRDGGDLCRYAL
                     DRAISLSGSASGYLAFLNEEETAFRITTWSQSTLDLCRVADKNTEFAVAKTGLWGEPV
                     RTRRPLIINDYAALDRGKKGTPPGHPPLAKYLGVPIIDGSRIVMLVGLGNKSTDYTDT
                     DVQQVTLLMGSLWQVLTRKRMENHLTESEKRFRSYFELPLAGIAITSPDMRWLMTNSK
                     LCSMLGYTQSELQALTWADLTPEDDSQREMDQIRKVIAGKQESFTLEKKFRRKDGTWI
                     DVEVSAMPVRKPDGSVDYFVALINDISPLLVTKEQLQVSNDQMLATLEELRATQDSLN
                     DYCHKLEREKQALRRSETRFRTMVETAPSLLFILDREGKIEYASPHAGDFSGYQPDEL
                     KEIGIAGIIHQRDAGKVAEEISRAIREGSGFRDIEFVATRKDGTSWFASCSMEPLPDE
                     SGTLCGFLAQIMDVTSRKEAEEALRQSEERLRKLVETINDVVFSLDPDGRITYVSPAV
                     TKVLGYLPRELEGRPFTEYLPSRNADSVFQLYSGLKGGERPSFPHRELQVVTQSGEER
                     WCRVSLIPIWTEGEFSGCSGTLTDIHEQWKAREELKNREALLQGILRATPAGIGVIRD
                     RVFVFVNEQICHMTGYSREELVGKSSRIFYPSDEEYQRVLNSYTLREGERAVASVEST
                     WIRKDGSLIDVSISVSPLEEVDWSGPLIFTVTDITEQKRQENALLESELSLRTFINAI
                     PGPSFLLGKGGEIIAANDAFWERYGGGKNHPPGTTFYSLVDRETGEIIRDHVEDALRL
                     GRISRFEMMHDSRSLIFDVSPVRDTQGRFSRVAVFSVDITDQKRAQEMLALYNRKLSL
                     LDRVTRHDAGNLIAAVKSYHDRVKKQTDDPLILTYIHKGERNLQALENVLAFADDYQA
                     VGMRAPAWQDVNAVIRKVAGMHDLKNVTILLDCDNLVVHADPLLEKVFSALIQNAIQH
                     GRKTTRVSFSYQKNDNGIILVCEDDGIGIAPERKEEVFEMGVGENTGFGLFLVREILA
                     MTGFSIRETGEPGRGARFEIAIPAGSFMIGTKDMQTGP"
     gene            complement(18319..19098)
                     /locus_tag="PK679_06460"
     CDS             complement(18319..19098)
                     /locus_tag="PK679_06460"
                     /EC_number="1.2.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018493 - formylmethanofuran dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit C"
                     /protein_id="HPC55631.1"
                     /translation="MRVILKTRPRKKPHVPIEAEGIIPQNFLRKNDLTVYEGNRERHL
                     EDLFFVTVEGPAVSPDQVEIILTGDTGRIKRVGEYMNAGRIIIEGDIGMHCGNFMSAG
                     EIIIRGNADAWLGREMRGGRILCEGTAGDYCGAGYRGEKRGMRGGTIEVMGNAGDFVA
                     EYLSGGEVIIHGNCGDLPGVEMRGGTLVIRGNCSRPCGNMTGGTCMVMGDPGELLPSF
                     RRNGSAEVEFGGKKFRMAVFRGDVANRGKGTLMVREDTGSP"
     gene            complement(19095..20798)
                     /locus_tag="PK679_06465"
     CDS             complement(19095..20798)
                     /locus_tag="PK679_06465"
                     /EC_number="1.2.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit A"
                     /protein_id="HPC55632.1"
                     /translation="MTQGILIKNAYVIDPLSGIRGEIMDIAIRDGRIVEDALPGSEVI
                     DAGGCLTLPGGIDSHSHVCGTKVNFGRYMSPEDMRAGRTSRKGVMHVTSGYSVPTTFG
                     NSYRYSTMGYTTVLEGAMAPLEARHTHEEFTATPHQDMLANTLFDGNWSVMEAVREKD
                     VKRAAAIVAWTLAAVKGFAIKLTNPGGTEAWGWGKDVSHIHDPVPHFEVTPAEIISTM
                     IQANEILRLPHSVHLHCNNLGVPGNFRTTLETMDLAPPAGGDRQTLYLTHVQFHSYGG
                     TTWRDISSKSEEIARSLNSKPQVVIDMGQIMFGRTTTMTADGPMEFKLYMLHHNKWSN
                     HDVELETGSGIIPVYYSRKSLVNCVMWAIGLELALLAKNPWQCLLSTDNPNGAPFVKY
                     PEIIALLMSRRMRENERKEIDPRTEHYVPLFALDRELDWYDIAVMTRAGQAKAMGITR
                     IGKGHLSPGAQADVAIYPLKPDNLDPSVDYQQVMAGFSRTLYTIKRGRVVARDGDVVV
                     EGANSTIWTRSRVPPEYDMGSDPEFIRKFDQYYTVRLRNYPVQDVYLPRGVCIETEAA
                     L"
     gene            complement(20795..22081)
                     /locus_tag="PK679_06470"
     CDS             complement(20795..22081)
                     /locus_tag="PK679_06470"
                     /EC_number="1.2.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit B"
                     /protein_id="HPC55633.1"
                     /translation="MRIEDVVCPFCGCLCDDLVVSVEGTKVLSVENGCTLATEKFTGD
                     HRLAHPIRRTGGAWEKTTYDDAIRETAEILLDAERPLLYGWSGTFVEAQTLGVHMAEL
                     LGAVIDNTSTVCHGPSILAIQEVGHPGCTLGQVKNRADVIVYWGANPIEAHPRHMSRY
                     TTFTDGFFVKSAFRDRKVIVVDIRETDSSEIADEFVKVTPGGDYAVLTALRMIVRGKG
                     DLVPATVSGVTREQLFRVAEICLSARFGAIFFGLGLTMSRGKSKNIRNAIELTEELNR
                     HTKFTISPMRGHWNVYGSNEVFTWITGYPYAVDFSRGIAFYNPGETTSVDLLRRKECD
                     ACLVVASDPGAHFPRACAEHLASIPTVQIDPHVNATTHLSRIQIPVAVTGIDAEGTAY
                     RMDGVPIRTRKLFSTGYPDDVAVLGRIYSLVKEAKG"
     gene            complement(22071..22460)
                     /locus_tag="PK679_06475"
     CDS             complement(22071..22460)
                     /locus_tag="PK679_06475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin dinucleotide binding
                     domain-containing protein"
                     /protein_id="HPC55634.1"
                     /translation="MNFLMTTGRTIRQGSYVERKNTAPYRDEASCIRMNPVDMFDLLV
                     EEGDAVRVTGAGGSVVMRVRQDPMLPRGLVFVCLGPYANALASPWTHGTGMPDFKTVP
                     VSIEPTTEQPLPVSALMRECGGMPYED"
     gene            complement(22457..23068)
                     /locus_tag="PK679_06480"
     CDS             complement(22457..23068)
                     /locus_tag="PK679_06480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC55635.1"
                     /translation="MAISLVAYIREFARWEWARKFLAARTAPLVIPPYFRNYPELTGK
                     TCTHHLFCMMACPAPGAIDVIRTPEGWQPRIHIGHCIRCGLCVEACPNGVLSSGRILE
                     SMFRDNTRLSFSFKIDVDLDKCMGCGNCAVACPVNKLIDAQMSHGGRASTDDLLLKLS
                     DGKCRVLHVEKCTGCKTCEHHCPNEAISVARLLEAVHAPEEVP"
     gene            complement(23071..24159)
                     /locus_tag="PK679_06485"
     CDS             complement(23071..24159)
                     /locus_tag="PK679_06485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent hydrogenase large subunit"
                     /protein_id="HPC55636.1"
                     /translation="MKRTVDVSIPVGPVHPCWKEPARVKCETRGEYVVSAEVELGYMK
                     KGIERIMKGRPWQEVMFLAERVCGICSVIHNMVFIEALEHISGIEVPRRAALLRVIVN
                     ELDRMQSHILANFSYCYTIEHETLAMYLLDVREKVMDQLERITGARVTCAYIVPGGVR
                     FDLRPEDAQALRQSLSAIEQEITRYTDMFSSGPLIALRSKGIGILTKEAAREAYAVGP
                     TARASGLGDIDRRLRHPTYQSLGFSPVVRTEGDNYARIMVRFQEIVQSIGLIRKCLDE
                     LPEGPIRGGGIPGAGEIAYSGEAPRGELSYFVKTDSAGRVLEISIQTPSIMNIEACCH
                     YMLKGVSSLADVTSTFVSSDPCIACTER"
     gene            complement(24156..24611)
                     /locus_tag="PK679_06490"
     CDS             complement(24156..24611)
                     /locus_tag="PK679_06490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55637.1"
                     /translation="MTFLQKVKNFVRSRSIHVAYVDVGSCNGCDIEVLACLSPRYDIE
                     QYGIFVHNNPREADILLVIGAYTPGWEEKLRGLWEKIPPPKAAIAIGNCPISGCLFAR
                     PHTLVDPPVAKHIPIAAQVPGCPPRPTEILSAILSVAPAIFADYEVKTK"
     gene            complement(24608..24997)
                     /locus_tag="PK679_06495"
     CDS             complement(24608..24997)
                     /locus_tag="PK679_06495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1959 family protein"
                     /protein_id="HPC55638.1"
                     /translation="MKEALYEKDLTALKYAILESRRHDRMVREIAADLGIPHLLLRRY
                     LMENLDMLLLENLPARYEQGKKFQQGLPEVERALSSHLYTRAVPLVDERVMDTIVTAT
                     KDRIAAGIPLSEAVSAGKAMIRQVILR"
     gene            complement(24994..25236)
                     /locus_tag="PK679_06500"
     CDS             complement(24994..25236)
                     /locus_tag="PK679_06500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55639.1"
                     /translation="MIRVVLVAAFLIYILVIAVQVWNRPSLWLEGFLIGAALAAAVAM
                     YWFRDRIILDRWEKAALWAAVLLFLVYGLARLGGLV"
     gene            complement(25233..26075)
                     /locus_tag="PK679_06505"
     CDS             complement(25233..26075)
                     /locus_tag="PK679_06505"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="HPC55640.1"
                     /translation="MIGELLFGTVFGLLLLGIHRKVIARIQRRPGPPVWQEILHMLKF
                     SFKTTWVPATASATLFVGVVLVAIGIWTAALFVVLSGGSLLIIFAVYMLHKIVEHGFG
                     LSSGSPYGKFGGVRSVISAASEIPLFVSVAAIGLFTRSLMISDIVAYQEVHGPLLLTV
                     PLAGLAMYLVVLSKMPFGPFSIVESKELVSGYKTEHFGVWRAGLEVCNGLKTYVLLTT
                     FLLVFVGSLPFLLLLLGMLVLTVSLSFACALCPMLSPYDSVTVQTIIAGLMLAYVSIL
                     VVMP"
     gene            complement(26078..26293)
                     /locus_tag="PK679_06510"
     CDS             complement(26078..26293)
                     /locus_tag="PK679_06510"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55641.1"
                     /translation="MTPHVKKSQALAVAVVSALAGIAATLLTLAGVLPPHADAAAWVI
                     AFPAFVLGLYLYWMAREGDPDIPFVGY"
     gene            complement(26290..26946)
                     /locus_tag="PK679_06515"
     CDS             complement(26290..26946)
                     /locus_tag="PK679_06515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55642.1"
                     /translation="MNEIGGVPLFFLEFGDIVAYFSPFTLTLFLLALVFSVFVIVSRP
                     ERQIDIAFGADAFFAKEISLPELRFRRFMAIACGLACMGAMVTGDVFDFTLFVSLVGI
                     CNVGIVAAVRTYHVQDAAYQYGLVALAGTVPLFSAAAIVAATTGTLSMLELASPAAPA
                     VPLIARALLVLGVMGEGMAPFYAAKAEMFRAPGAPYVIMCSLSSLLIFLRVTEVVLLL
                     "
     gene            complement(26943..27548)
                     /locus_tag="PK679_06520"
     CDS             complement(26943..27548)
                     /locus_tag="PK679_06520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2105 family protein"
                     /protein_id="HPC55643.1"
                     /translation="MAWNEYSFGLLVVFLAALVGFMALARERDDLHKLLLVDLVEVAS
                     IAVIALLGTDLAEALILPGLVVGIAELLALSQLYIAKEGLAGVPPRGLNIEVVQKSPA
                     TVIIPGFLVVYGIVLSGFTGGGIAALGLVFYFMSHRFLGDFHVLELASGISWALWVAA
                     FFVFMFAPAFWFLALMGAAVGILLKVITKISLVGVMWGEAE"
     gene            complement(27552..28001)
                     /locus_tag="PK679_06525"
     CDS             complement(27552..28001)
                     /locus_tag="PK679_06525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2106 family protein"
                     /protein_id="HPC55644.1"
                     /translation="MIIQKISRVLSNYDNILPLFAGACAILAVIALLSLPLPYFEDQL
                     YPKQIVPGSTLNPYDRGGPPFTQADIRLQYPQNSPTAGYVTAYLTPFSLFLSRTTMYM
                     GTTIVAHPGGILDEILYNTRGLDTVVEPTILFISFAIAAYIFHRRED"
     gene            complement(27998..28237)
                     /locus_tag="PK679_06530"
     CDS             complement(27998..28237)
                     /locus_tag="PK679_06530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2107 family protein"
                     /protein_id="HPC55645.1"
                     /translation="MTPEFLIGLFLILAGTVGTAFPKPKTYLNRLINLEIPGIGILLV
                     MLSYNEALALLTYGGVSALSVFIFVRVLQKREGKT"
     gene            complement(28234..28464)
                     /locus_tag="PK679_06535"
     CDS             complement(28234..28464)
                     /locus_tag="PK679_06535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2108 domain-containing protein"
                     /protein_id="HPC55646.1"
                     /translation="MNETVIVVLAALAVLGCVLAIRESDPYRKLIALSLIVGGTIPFI
                     VDRGLLDVAIAVALIFPLSTIFILMACPGGEP"
     gene            complement(28461..28715)
                     /locus_tag="PK679_06540"
     CDS             complement(28461..28715)
                     /locus_tag="PK679_06540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2109 domain-containing protein"
                     /protein_id="HPC55647.1"
                     /translation="MTPADMALVLCGTVALYAGVRVALEPDTLRKLPFLNVLSFAITG
                     LIALLLPHPLGIVAAAAYFVGSTLESNAIASTYAGGLDRG"
     gene            complement(28712..29209)
                     /locus_tag="PK679_06545"
     CDS             complement(28712..29209)
                     /locus_tag="PK679_06545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55648.1"
                     /translation="MDTVLLTTVHILVAAAVCWLNFITIDMFFKLPEKGGVVGATAIA
                     RHIEAGGGSLEGGTMMGNIVSSPDASAGTLLAACGVFIAGIPGGLLAALLVFIGNRIC
                     HDRGYAGTTGCLTATFLIYGFTLAGFSAAEFIAGMVIAILSIQGISHVYASRLLSTIW
                     KVRWG"
BASE COUNT         6092 a         8449 c         8483 g         6237 t
ORIGIN      
        1 agcccccggt ccgaaaaagg aaaggccgcg ggttcgaatc ccgccaagtc catgggaacg
       61 tttttttgga ggatgagagg gtactggaag cgaccgggag gtcgctgcgg ggtcgagggg
      121 cggagccccc ggtccgaaaa aggaaaggcc gcgggttcga atcccgccaa gtccatggaa
      181 ttccttttaa aaattttaat gcacaataaa gcaaacggaa aaaagagacc cgtccggatg
      241 gtcacttctt ctgcatcatt gcctgcactt cgccttcgag tgtatttttc agtttttcga
      301 gcgcttcgtt ctggtctgat gtcgtggtga tggtgaacga attatcgctc ttcatgtcgt
      361 ggtagttcac gatatactcg atctggccgt cctttccttt ctttggttca atgatgagct
      421 gcgccatgaa ttttcgcggc aatcattggc agtgctgcca catcttcctt ccggtcacac
      481 cgatcagtaa taactatatg gattccgtag aaaaatggaa tgctgcagtc atgcaggcac
      541 agggctcgta gatcaggggt agatcgtcac gtttgcaacg tgaaggccac gggttcgaat
      601 cccgtcgagt ccatgaatat gtgtttttcc tttcctccat tttttatggg aaaaaaggtg
      661 atttccagta ttcccgggtt ttgagttgat taagtcaggg aagagatatc gacttaatac
      721 gagatccgtg gtgaaatttt ctccgggtcg tgactcccgg gccacggcgc gggctatctt
      781 catgaggagg gtgcgggagg agcggggcag atacaactgg tcacactgcc cttcaaaata
      841 gtaaagagaa aaaaaatcag agaatgatct cgatatcgag tttctctgca agttccttgt
      901 acctgttccg gatggtcact tcggtgacac ccgcgacctc ggccacctcg cgctgggtcc
      961 tgcgttcacc gccgaggatg gacgagatat aaatggctgc tgctgcaaca cccgtcggac
     1021 ctcgcccgct ggtcagttct ctctccccgg cctgcctgag gatctctacc gcccggctct
     1081 ggacctcccc cttgaggttg aggcccgaac agaaccgggg cacgtagtcg atcggggagg
     1141 tgggaagaag cttgaggcca agctcgcggg agatgaaccg gtacgtccga ccgatctcct
     1201 tgcgggacac acgggatacc tctgcaatct cgtccagtgt gcggggcacg ctgcactggc
     1261 ggcacgctgc atacagggct gctgctgcaa caccctcgat gctccgcccg cggatgagat
     1321 tcttgtcgac tgcatcgcgg tagacaacgg cagcggtctc cctcacgttc cgtggcaggc
     1381 ccagtgcgga tgccatccgg tcgagttccg agagggcaaa ggcaaggttc ctttcggtcg
     1441 cgttgctgac cctgatgcgc ctctgccact tccgcagcct gtagagctgg gcacggttct
     1501 tgctcgaaat ggccctgccg taagagtccc tgttcctcca gtcgatcatg gtggagagac
     1561 ccttgtcatg gatggtgaac gtcatcgggg cacccacacg tgagcgcttc atccgctggt
     1621 catggtcaaa cgcgcgccac tcgggtccac ggtcgatgaa atcgtcgtcg attacaagac
     1681 cgcagttctg gcatacgagc tcggcacgct cgtagtcatg gaccagctgg cggctcccgc
     1741 actcgggaca gaccgtctcg gtgtggtcct cggccttctt ttcatgttcc ttcaccctgt
     1801 ctttcagcct cttcttgagg gcttccctct ccttctggag caccttgagc ttctcgactt
     1861 cctgcacatg catcactccg ttgcttaccg gatgaacaac ttctccccag ctgtcactgc
     1921 acacggcccc ttacagagaa ctgcggcaag cggcgatgag acatttccaa aaacatccac
     1981 caccctgccg accggtttca tgcgcctgtc aatgacctcg ctgtaaagcc tcgggagttg
     2041 tgccgcatcg caccggacaa ccaggatacg tgcccctatg gcgtgaacag ccagaccaat
     2101 ggatttcaca cgaaaaacct cttattcctc tgcctgcgtg aacagactga aggatttagt
     2161 aatctatata tatggaaatt tgttatattt aaacctattg aaaatgtata aatatcattt
     2221 tttatggaaa agaaattcct ctatattaaa cgagaggatt cgctcacact gggcggacga
     2281 gaggcctgca cccattccaa ccacttttct tgcgcgcgcg tccatgagat cacccggcga
     2341 atgggcatcg gaatcgatca ctaacacgca ccctgattca agtgccacag ctgcgacatg
     2401 gccattggtc ctgttatgac cgcaccggga ggtcagttcg atcgcaacgt cgttgctgca
     2461 tgcaagagcg gcctcctctt ctgtcaggaa accggggtgt gcgaggacat cgacatctct
     2521 gcatccgcat gctgccaggt tcgttccggg tgccacaggt tcaagtactg tctccccgtg
     2581 gacgacaacg atttcggccc cgcacttctt tgcttcccgt gccatttttg gaatcatccc
     2641 cggcgggaca tgggtgagtt caacaccggg aaggagggtg acaccgtagt cttttgcgag
     2701 agggaccagt ttttttgtcg cggatatcag ttcttccacg ttcgttgcat cggcatggtc
     2761 cgttatcccg acatgggtat aaccgagaaa tgcaagcctt cggacgagct ctgccggcag
     2821 catgtctcca tcggtaagaa ccgtgtgggt atggaggtcg tacactctct cacttcccct
     2881 gggcgaggtg ggatgcaatc ttccggagaa gtttttcctt gctctcgctc cacgtgacaa
     2941 caatccggcc ttcctttaac caccagcggg ccgggaaatg cttttgttct gatcggaaca
     3001 cgagcccgga ccgctttgcc gcccgttcga ggtctgcaag cgtggggtcg ctgacggcac
     3061 ctgacagggc cactctgcgc ccctggcccc gtttaagggc ggaattgaag tagcagggat
     3121 agattatcct ctcgcctttc atccttcata ggtgggaatg gtgaacctat aaactgtgca
     3181 gcatccataa tatctggtat gcaccatatc gacgtccgca ttgagaagga tgtctacgat
     3241 atcaaccgcc gcatagccga agagaacgcc cgcaccctcc ggaaacacaa tgtccgtgca
     3301 ttcgacctcc tgggagcaat cggctccgga aagactgccc tgatagagaa agtcgttccc
     3361 ctcctgcagg agagaggttt gagaccgggg gcaattgcag gagatgtcta tggcgatgat
     3421 gattaccaga ggatacgggc gctcgggatt cccgcagtga atgcaaatac gggaaaggaa
     3481 tgccacctcg atgcacacct ggtggagcac gcactcgaga gtatggatct cgacagtatc
     3541 gatatccttt tcatcgagaa cgtcggcaac atggtctgtc cgaccgattt ccccctggga
     3601 gccgagaaga ggtgcgtcat tgtcagctcg acggaaggtg acgacgtggt gaacaagcac
     3661 ccgatgatgt tccgcgggtg cgacataggt gtcatcaaca aggtcgatct cgctcctctc
     3721 gtcggggcag accttgaccg catggaaaac gacatgaggc ggtatcaccc gggaatgaaa
     3781 gttttccgga cgaacctccg gaagggtgag ggggtcgtcc cgttccttga tgcccttctc
     3841 gggtgagcgg tgagttttat tagggcaggg cacaaatatt ataaaacttc ggcaggagcc
     3901 tttcctgcca ggaaagacca caataatggg ataatgacag gggagatcgc atgctctggc
     3961 aaggaagatc ggtaaggaag cccacaggcg gcaggtaccg gctccgactc gtaaagagga
     4021 ggagagagat aggctcggca ccaacggaca gtcatatcgg gaaggaccgt cgggccatcg
     4081 tgaggatcac gggcggtaat atcaaggtca ggacaatgcg cgccgaatat gccaatgttg
     4141 cagatccgga ttccgggact gtcaggcgtg cacggatcga gacggtggag gaaaacattg
     4201 ccaaccccaa ctacgtccgg cgaaacctcc tgacgaaggg agcggtcatc aggaccgagg
     4261 caggacgtgc acgcatcatc agccgtcccg ggcaggaagg cgtcatcaac gctgtccttc
     4321 tcaagtaaag aacttttttt tccgccgggc tcgcccggaa ttttccttcc gctatcctgg
     4381 aagagctcaa aagtcgtatc cagaaatgaa catggtgagt aggaggagga ctgtggatgg
     4441 atacgacttt tgtcgtatat ttattgtatt gataaaaata taaatatttt catatataaa
     4501 aagggaacga tccggctaat tttttgatct ccacgcattg aatgattttc attgaatgat
     4561 ggctgatacc ttgcattcac ggaaagaaga caatggaacc acagtgtcgt tgagtttatg
     4621 atgcacagcc ccggttcgtt cggcatctgc tttaattttc aatgcataat cgtcaattgt
     4681 acggataatg ccagggataa aatgccgaac agttgatagc atgcggcaga taaaatgaga
     4741 tgatgaagca gaggagaccc ggaggagaga gatgagcctt tctttgacaa tcgctgcacc
     4801 gttccgccat tcccacaggt ccgagctcaa gaagaacgag atagtctatt atcttgcgtt
     4861 caagcagcac tggatgaaca tcgagcaggc taaccaggtc atctcgcgtg caatcgagga
     4921 agggctcatc gggatcgagg gtgacatgat ccgtcccctc tttgatgtct cgcgtgtcga
     4981 aatacctctg ggcttcaaac ccggcgcttc ggtcttccag cgatccgacc ctgtcgatga
     5041 cctcgttttc cgtatctccg aacggacggg aattccaaag ggttccgtgg tgtccgagat
     5101 aaacagcatc atccaggacg tgttccaggg gaacctcacc agcgaagcag cagcagtcat
     5161 cctggcaaaa cgtcacggtg tggagttcca ggacctgctc ccggcattga gggagcacgt
     5221 cctcacctcg tgaggaatcg acccctgccg gtaataccct gattttggta actggttaaa
     5281 aaaggagaat tttattccgt tttcccttca gcggcaggct ttgcgaagag ctcgtcaagg
     5341 gacttctcgc catactggac gatgcgcgca ttgatctgga cgaagtcggc cgttatctcg
     5401 ttgccacgga tggtctttct cctccgctgg ccttcccgcc ggggcttgaa ccctgcaccc
     5461 cccgagagga ggatcttccg cctccccgcg aacggaaggt tcctccgcgc aggtgtgcca
     5521 ttccgatcgg atcctcccgt gataaccatc ctgtacccct ggagcccgaa gatacctgca
     5581 tcaacctcgt caccgatgcg tttcccgatc agtgcacccg ctgctccgcc gcccacatcg
     5641 accttgaaag agcggccact tttctggtca gacagtacta ccttgaattc tgccatcctt
     5701 gtttcacacc tctggaaaag gaatctatca ttctcctgca gccggccgga aattattcgt
     5761 gacaggtcac ccccctgcac ccgcaaagga gcaccgggcc ctcttccggc agggcctcca
     5821 tgaagtacct ttacaattgg gtgactggta taataagtct atttccccca gaacgggttc
     5881 tctttccgtc tcatcgcggt gaactctgca aggacttcct gggtgtgaat ggggagatgg
     5941 gagagcatct ccttctcgag caccttgacg tgtttttcag ggacatccac gtagagttca
     6001 tcgtcgacgt ccagctgcct gcccacagtt gcaccttcga tggagatggc aacctctgca
     6061 cccgtctgcg cctccctgat gttctcctgg ttcagctgca tggacttcac gtgccccact
     6121 ttcctcccgt cgcgctggat gaggttgaca tcggtccgca gcgtcccgcc aaggacgcgc
     6181 acccccacca cggcagggtt gctctgccgg aatatgcagt gggggaggat gcggatcttg
     6241 gcaggaaaga tgatctgctc gaacttctgt tgctctatcc ttctcttgag atcgtccctc
     6301 cactggacgt aatcatcgac gagcttgtag ataacccgcc cctcgaaaac cctgacaggg
     6361 aatcccggtt ccctcaccat atcggcggca tcgggcaaca ggggtgtgga gaatgcaata
     6421 aggacccggt agtaagggtt ttttatggtc attgcctcga cgaggtcgtg ccggctcacc
     6481 gaacctacct cggcccgcat tacccctatc tccttctcct ccagttcctt gcagagggct
     6541 tcgagtgcgc cgatggtgtc tgccttgatg ataagcccct cgggcgagag atgcacgttt
     6601 atcgtctcca tctcccgccg tatcttctcc atcacggaat ccgcgtcacc gcgcacgaca
     6661 tggaccggcg aacctgcgat tgccccctcg agattcgggg cactcacctt gattccagca
     6721 gcggcagtca cggacctgac ccggcagaac ctttcctcca caaggatctc ctggaggggc
     6781 cggggctgga gaagagccct tacctttgtg acgatgatgc cgtcctgctt tgcaacggct
     6841 atctcgtcgc cgaccgagag cgtcccgtcg tagaggatga catcgagggt ggttccaagc
     6901 cccttctctt ccttgacctc gaggatcgtc cccatgcccg ggccgtcgat cgagagggag
     6961 agagcctttt ccatgtaccg ctgcgcaagt ccgatcatca ccatgagcag ctcggggatc
     7021 ccctcgccgg tatgggcgct gaccggtacg atagcaaggt tcctctggaa gtccgagaca
     7081 cggtcgaacc gttcggccga gaacccgagt tcggacagtt ttccgactac ctcgtagact
     7141 ttggtctcca ggagttcctt taccctctcg ttctgccttc cgaaactcgc aaggaacggc
     7201 tcgtcgcggt ttaccttcca gccatggatg cggtctatct tggttgctgc aacgacaaac
     7261 ggggtcttgt acgtccggag tatctggagt gcctcgagcg tctggggctg aaagccctgg
     7321 ttgatgtcca cgacaaggac agccatgtcc gcaagggcac cacccctggc acggagggtc
     7381 gtaaacgcat ggtgaccggg tgtatcgatg aagaggaggc ctggaacgtt gaggggaacc
     7441 ttctccatgg atccgctcat cttcctgatg gcctcgatgg gaacgatggt cgccccgatg
     7501 tgctgggtga tggcaccgtc ctccatgctc acaaccgagg agcccctgat ccggtccagg
     7561 agagaggtct ttccatggtc gacgtgcccg agcacacaga caataggagt cctgattcgt
     7621 ggcttctcac tcatttctct tcctccgggg tgcacgaggg gatggaaagc cctgatgtct
     7681 ggttatgcga gggggagaca gggaaaagtg gagacactct cttccctgac actgcccccg
     7741 actggtaccg tgcaatgtaa tggagcacca tgaattatat acgcaccggg gagcctctcc
     7801 atccggtcca aggatatctt aaagtgtgca ggggttcaaa aatgaagggt acatcctgcc
     7861 agggtggggt agttggttat cctaggggac tgtggatccc ccgacccggg ttcgagtctc
     7921 ggccctggcc tattcctttt ccgtccttga taactgcagg acatgcaatg aatgggatat
     7981 cgcctgctct cctgtcaccg tccccttctc cagaatgccc ttttggcatt tcatgcgctt
     8041 tgggccgcca tcagccgggg accatctgtg tctcgcatcg cgggcaggac atggtgtaac
     8101 agggcactgt tacgtgcctt cgaacgcggt aaccgcacat cgggcagacg cagaaagctg
     8161 gtatcatccc cccaggcgcc atcccacccc tctcgtggtc ttccatcatt ccgggtcagg
     8221 aatacctctg gttaatccgg aaaataaacg ttctccaggg ggacactccc ctcttctccc
     8281 gcaagtgagc atccgggaac gaccggggat cacgttccat cctcccttgg cctgaaaaag
     8341 tgctatatga caggaaaaag ggaaagattg ggggaaccgg cgaactgata gatttaaata
     8401 gggatacttc cccccattct atatagctga ttggtggagt gtatggaaaa atcagtcctg
     8461 aaatacctca tcctctgtgc agtcgttgcc ctgatagcac ctgcatcagc cgattctgca
     8521 acggaggcat cgaaagacca ggggatctac cgctttcata gcaacgttga tggtgcggaa
     8581 gtgtacctta acggccagct gatcggttcc atccaggact atatcctcga tgtgcctgtc
     8641 agcgcatcag ggccgtttta tcggaattat accctcatga aggaaggata caaaccctac
     8701 tcgggcatta tcaattccat tccgaagaaa ggacaggtta ttcacatcta cgttgtgatg
     8761 agcgcacagg ccatggtcga atacgggacg gtgcacctca tggtaacacc cgcggatgca
     8821 gaggtgacct gggacggaag tcctgccgga aaggtcccac catcagggat tctcgtcctc
     8881 tataacgtat tacccggttc ccattctctt gttatcggaa aggaggggta tgagacatat
     8941 tacgggtctt tgtatgttcc cccgaatgaa gttgtgaagt tccctgtcac actgactccg
     9001 atccaggcgg gggcactttc tgttgaatcc gtgcctgcgg gtgctgcagt cagcgttgac
     9061 gggcagtacc ggggtgtcac acccctcgtg atacgcgacc ttccggcagg aagccacacg
     9121 gtatccctgg caggtgaggg ataccaggag tacgtctcct ctgtcgaggt cacgggtggg
     9181 gcaactgcca cagtgagtgt gaccctcctc cccgcgacaa catccgtgcc ggccggccgg
     9241 tcaccggtat cgcccgttct catcgtttcg ggtcttggtg tcgccctcgt tcttgctggc
     9301 agaaagatgc tctgatccac tcccattctt ttttcatgct ttcagaaggt gcctgcgata
     9361 atacggtcat cctgtatgac gcagcgacgg ggacgcggga gccaaaaagc cggatatgcc
     9421 ggtcacctga agaatggcgg gctctccttg caccggaggt atacactgta acgcgtgaca
     9481 aggggacaga acctcccttt tcatcgcccc tcactcgctg caatgcagag ggggtctacc
     9541 gctgcgcgtg ttgcggcacc gacctcttca tgagcgggaa aaaattcaat tcggggacag
     9601 gatggccgag tttcagggcc cctgtcgacc cctgtaacgt gcacagggag agggacacat
     9661 cattggggtt ggaaaggatc gaagtgctct gtgcccgctg caatgcgcat ctgggacatg
     9721 tctttttcga cgggccgcca ccggagggga cacggtactg catcaacgga ctcgccctct
     9781 cgtttcatcc aggcagcaga aaatgaattg gaacagggag agaattggcc ccgtgacctc
     9841 tcctcccgga tgaaaacagg cattctcttt aatcactgcc gcgaaatgtc tttcatgcac
     9901 ttctgcgttc cccggtgggg ggtgcaacgt gaaggagagt gacggaacca tcctctcggc
     9961 agatgacagc gaattcctcg gggagctgtc agagtacctg gaagtccttg gcaacagcac
    10021 acgtctgcgt atcatcaggt tcctcgaaaa ggaggccatg gatgcccgga cactgtcgag
    10081 aaggaccggg atctcctacg agaatacaaa aaaacacctg gaaaaacttc tcggtgccgg
    10141 acttgtgacg cgggttccgg gacttggcag ggagacatcc aggggtatcc atcctgcctg
    10201 gaattacctc cccgtccccg gcatcctgga gaggatccag agggatctcg gtgtcattgc
    10261 ctcggttcag gataaaagag gacaggatgc ccttcagcag aggatagaaa gtgtcaggcg
    10321 ggaggtcggg aaggcgcttg gaacagcggg gtggatgctc cttgtcattg gcggtgaatg
    10381 ggacgggaaa accatttgcc tccaaagccc gaggactgaa ctggggaggg gaagggaaga
    10441 aggcatttcg ggagaagggg gcataacacg catcgctttt cctccatcgt accggtctgt
    10501 cacgcgcctt gaaaagcccc atgcaattat ccggacaggg agaggcgaat gtacaatcga
    10561 ggatgccggg agcaggggag ggacctttat caatgaccaa aagatcattc cccatgatca
    10621 ggtacccctg aaggatggcg acaggatcat gctttcccgg ggagacttcc cggtcacact
    10681 tctcgccctg aaaagcgata cggtgggaga aagaccccat gagtgagggc agctcgtcat
    10741 tcctcaggtt tactctcatt gtttttgtac tggtactggt atccgctgca gcatgccatg
    10801 cagataataa caaggctatc aaaattccac agtccctcac gaacaaatcg ataaaggagg
    10861 accttttcgc atttctcaag cagggggcag agagtgcgca gagtatcctc cgcccgacca
    10921 tgaccatgcc ccagatcacg ccctttccga ccgtgactgc cccgggtaag ggtgcaatac
    10981 cgacacgccc cctgacaggg cagcagacag tgactccgcc agcgactctc cgtccgatta
    11041 ccacggaaac gtccctgccg ataacgccaa cagcaacaac tcccgcacca gcggcaacac
    11101 aatttacgca gcaaaccacg atatcccccg gaggaacgac gcaaccatcc gcggggactg
    11161 tatcatggtc cggtattggt atcctggccg gccttttcct ctctgcctgc acaggctacg
    11221 tctacctggt acacaacagc atccgtcgca gggactcaat gcccgttgca tggtgggtcc
    11281 gctactcccg tatccttgcc ggattccatg cagcacttgc tgtcgtgttc gtggtgatgg
    11341 tactgggcat cgtcctccct ttcctggaca ccgcccggga gacacccgtt gatcccctca
    11401 tctccctttc cagtggtgca attgcaggtt ttgcagcgat atcctcgctt gtgatgtcat
    11461 acttcaccct ttccggacat ctcccgcggc gagtgggaac ggtccatgca gcggttgcac
    11521 tggcaggaac tctcctcata cccgcgcttg ccttcttgca gggtagcgca ggtccagacc
    11581 ctcttcggat agtccccttc ctgtcaggac tcgttctggc agtggtgcag gcacgggaag
    11641 gcggattgag gtttggagtg cctcccagga atgcgccact tccagacacc ctccttttcg
    11701 aggatgaaaa tctccccggg cccggacctg actttcccgc ggcgctttcc agccggtatt
    11761 acggggcacg ttacatccac cacggcggaa ttgcccacgt cttttccgca tacaggagat
    11821 ccgatggcgt tgcggtcgcc gtcaagatcc ccatcaggac tgatgagcag acggggaaat
    11881 cattcctccg ggagatgaaa gtgtgggagg gactggtcca ccccgggatt gtccggatct
    11941 attcagcaaa tatcctccct gtcccctacg tcgagatgga ataccttccc cgcagcctgg
    12001 cggacacgcc cgtccccatc agtcccgccg cgtcgttagg gataatccgg aaaatcggag
    12061 aggcactcct gtatgcacac gatcgcgggg ttatccaccg cgacttaaag cccgaaaata
    12121 tcctcgtcac ttccggaggt gaaccccgga tcgctgactg gggccttgcc agggacgaga
    12181 agggaacgtt ccagacgaca ctccatggtt tctcgctttc gcacgccgct cccgaacagc
    12241 tcgatcccgg caggttcggg acaacgacgc agcagactga catataccag cttgggatca
    12301 tctggtactg gcttgtgtgt ggtacacagc cgttctcggc aggaagcatt gcagaagcga
    12361 cgagggaacg cctggaaggg gaggtggtcc cgccttctgc ccgcgtgccg gggattgagc
    12421 tcctggatcc ggtcatcctc aggtgccttg cccggaaccc gtccgaacgg tacagggaca
    12481 tgcgcgaatt cctgaaagat atcctggacc tggaaacaag gcttggagga aagaatggtg
    12541 gtgccggcac cggtaatgcc tgactgcccg gccctgcccg ggaaaggatg ctccgggagg
    12601 cagcatgaat aaacccggtc tggcagggga agggattcct gttgccgttg ttgcgtgccc
    12661 cgattacatg ccacaaaacg tttcacgtgc actcaggcgc gctttagact tagtgggagg
    12721 tctcccggct ttcgttcctc ctggttcccg tgtcctcgtc aagccaaacc tcctccaggc
    12781 agtcccgccc gagcgggccg tgtgcacgca tccggtagtg accggtgaag tcgtccgatc
    12841 cctcacggac gagggctgtt ctgtcaccgt tgccgacagt cccggcgggg gaacccggta
    12901 cacggaaagg aacatggaac gtgtctacag ggtttgtggg tatgcacacc tcccggaaga
    12961 aacaggctgt tccctgaacc atgactgcag gtaccgggag attaccgtcc ccggagggtc
    13021 ggtctgcacc cgctttcccc tcatatatcc ctattttcag gcggacagca tcgtgagtgt
    13081 ctcaaaggca aagacgcatg tcctgaccct tatgacgggc gcgacaaaaa acctcttcgg
    13141 gctcctgccc ggcctggaaa aacccctctt tcactcccgt tttccggacc ctgccgtttt
    13201 ttccgacatg cttctcgatc tcctcctcgt ggtccggccg gctcttcaca tcgtggacgc
    13261 catcgtggcc atggaagggg atggtccgat gtcagggtca ccccgtcccc tgggtgccat
    13321 tgtcgtcagc ccgagtgccc ttgcagccga tatcgtcctc tgcaggctca tgggcatcga
    13381 tcctgcccgc gtcccctacc tcgcacgggc tgctgcccgt ggcctcgttg ccctggatgg
    13441 cagtggcatc gatctcaggg gagatccggt ctccatgctg cgcggggaag acttcaggat
    13501 accggggact tatgcgtcag gaaagtccgg gttctccatt ccacttgtct tccgtgttgt
    13561 ccaccgcctt gggaaagtct accagctccg cccggtcgtg gatggatcgc ggtgctccgg
    13621 atgcgggagg tgtacagttg cgtgcccgtc caatgcagca gcgctcgttc atggcagggc
    13681 cagcatcgat ccccggaagt gcatccggtg ttactgttgc cacgaaatgt gtgagcaggg
    13741 ggcaatccgg ctcgaacgtg gggttgtggg cgcacttatc catgccattg cgggcgaaaa
    13801 acgtcacgaa gagtgactat tcggttcacg cgggcaaatc ctcccgtgac tctttcctct
    13861 ccgcggagca gaatcgggtg gtctctggtc atttcattga accgcaggta tccaccaaat
    13921 ttaaatgcgt gttccatcca ccatagtgcc gaggtgccaa aaatgagaga caccataaaa
    13981 ataatgctgg caatcatgac gtttgccgcg gtcccgatgg tccagctcct cgctccatga
    14041 cgggaaggtc caagggtttt ttaaccctcc cctcatgtcc ctatcagaaa catcaaaccc
    14101 ttatcttttc acaattgcag cacagtgcca ggtgacaagg aagatgtacc cgccgcacat
    14161 tccacgcctc ctcgaaaagt caaggaaaag accggacctt gcccgtatca tcacgcgggc
    14221 ccgcctggcc taccggaatg caatatcccg gaatgcatgg ccccggtgaa ccatgtctct
    14281 gcccgtggga agaagccata aaaaggagcg aataagccct gggttaacct tatatcatgt
    14341 tctttccatt cctgttagtg aggtgattgg ttcatgtgca ctgtcggagg cccggtggat
    14401 cttgaagttc cccctgacag ggtcaagggg aagaattacc ggtgcaggga atgtggagaa
    14461 aaattcaggg gagtgggaaa acaccctgtg tgcccttcct gccagtctga agacgtggaa
    14521 gaagtctgaa aggtacggtt ccacgtcaaa aaaaaatgga atatggaccg gcccgggacg
    14581 ccggatctgc acttttttcc ccatgcatcc gttggatgag aaccatcctt acggtatcag
    14641 gaagtttttc cgggactatg gcccggtctg catgtctttt gtaccaatca tgaaggaacc
    14701 tgcgggaatt gctatctcga aacgcgcccc acgccccggt tcccctgtct ccctgataga
    14761 aaatccggtc atcgcgagga tctcgcggac aaggaagagg ccaaaaccgg tattttcacc
    14821 gactcccatt tcgaagactt cttcctttct ttcaggggca attccgatac cgtcatcctc
    14881 gcagaccagt atgatcccgt tgtcattctt ctggtatgaa aaggagaccc gtgtcgtctt
    14941 tctgccgtgc tggattgcgt tctggatgag ggcagaaaag accttttcga gcagcggatc
    15001 tgcgtggaca accagattgt cgcagtctaa gaggatagtg acgtttttga ggtcatgcat
    15061 tcctgcaacc ttccggatga cagcgttcac gtcctgccag gccggtgcac gcattccgac
    15121 tgcctggtag tcatctgcga aagcgagcac gttttcgagg gcctgcaggt tccgctcccc
    15181 cttgtggata tacgtgagga tgagggggtc atccgtctgt ttcttcacgc ggtcatggta
    15241 gcttttcaca gctgcgatca ggttccctgc gtcgtgcctg gtgacacggt caagcaggga
    15301 aagcttcctg ttgtataacg caagcatctc ctgtgccctt ttctggtctg taatatcgac
    15361 agagaagacc gccaccctcg agaacctccc ctgcgtatcg cgtacagggg agacgtcaaa
    15421 gatcagggaa cgggaatcgt gcatcatctc gaagcgggaa atcctgccca gcctgagtgc
    15481 atcctccacg tgatcccgga tgatctctcc cgtttcacgg tccaccaggg aataaaatgt
    15541 tgttccgggc ggatgatttt tgcccccgcc gtagcgctcc caaaaggcat cgttcgctgc
    15601 gatgatctcg ccgcctttcc cgaggaggaa ggacggcccg gggatcgcat taatgaaagt
    15661 gcgcagggac agttcactct cgaggagtgc attttcctgt ctcttctgtt ccgttatgtc
    15721 ggtaaccgtg aatatgaggg gtcctgacca gtccacttcc tcgaggggcg acacgctgat
    15781 ggagacatcg atgagtgacc cgtccttccg gatccatgtg ctttccactg atgcaacggc
    15841 acgctctcct tctctcaacg tgtaactatt caggacacgc tggtattcct catctgacgg
    15901 ataaaaaatt cgtgaactct ttcccacgag ttcttcgcgg gaataccctg tcatgtggca
    15961 gatctgctca ttgacaaata cgaagacacg gtcccttatc acaccaattc cagccggagt
    16021 cgcccgcaat atcccctgga ggagggcttc acggtttttg agttcttccc gggctttcca
    16081 ctgctcgtga atatccgtca gagtacccga acagccggaa aattcacctt cagtccagat
    16141 ggggataagt gaaacccggc accaccgctc ttctcccgat tgtgttacca cctggagttc
    16201 cctgtggggg aaagagggac gctccccgcc tttgagcccg gagtagagct ggaagacaga
    16261 atcggcgttt ctggaaggga ggtattcagt aaacgggcgc ccctcgagtt cccgggggag
    16321 gtacccgagt acttttgtga cggcaggact cacgtacgta atcctgccgt ccgggtcgag
    16381 tgagaagacc acgtcattga tggtttccac gagtttccgg agcctctctt cgctctggcg
    16441 gagggcttcc tctgcctcct ttcgggacgt cacatccatt atctgggcaa ggaagccgca
    16501 gagggtcccg ctctcgtcag ggagaggttc catggaacag gaggcaaacc aggacgtccc
    16561 gtccttcctt gtggcaacga actcaatatc gcggaaaccg gaaccttccc gaattgcccg
    16621 ggagatctct tcagcgactt tccctgcgtc cctctggtgg atgatacctg caataccgat
    16681 ctccttcagc tcatcgggct ggtatcccga gaagtccccg gcatgggggc ttgcatactc
    16741 tatctttcct tcccggtcca ggataaagag gaggctgggt gcagtctcga ccatcgtccg
    16801 gaacctggtc tcgctccgcc ggagggcctg tttctccctc tccagcttgt ggcagtaatc
    16861 gtttaaggag tcctgggttg cccggagttc ctcgagtgtg gcaagcatct ggtcgtttga
    16921 tacctggagc tgttccttgg tgacgagcag gggagagatg tcgttgatga gggctacaaa
    16981 gtaatccaca ctgccgtcag gcttcctgac gggcatggcc gagacttcga cgtcaatcca
    17041 tgtaccgtcc ttccgcctga actttttctc gagcgtgaag gattcctgtt ttcctgcgat
    17101 gaccttcctg atctggtcca tttcgcgttg gctgtcgtct tccggtgtca agtcggccca
    17161 cgtgagtgcc tgtaactcgc tctgggtgta tccaagcatt gagcagagct tgctgttggt
    17221 catgagccac cgcatgtccg gcgacgtgat ggcgatcccg gcgaggggaa gctcgaagta
    17281 cgaacggaac ctcttttcgc tttcagtcag gtggttctcc atcctttttc gtgtgagaac
    17341 ctgccagagg cttcccatca ggagggtgac ctgctggaca tcggtatccg tgtagtcggt
    17401 agacttgttc ccaaggccca ccagcatgac gatccgggac ccgtcgatga tcgggacacc
    17461 caggtacttc gcgagggggg gatggcccgg gggagtcccc ttctttcccc tgtcaagggc
    17521 ggcgtaatcg ttaataatca gggggcggcg tgtcctgacc ggttcccccc atagcccagt
    17581 cttcgcgacc gcaaattcag tattcttatc tgcaaccctg cacaggtcga gggtggactg
    17641 tgaccaggtg gtgattctga aggcagtctc ctcctcgttg aggaatgcga ggtacccgct
    17701 ggcacttccg gagagtgata ttgccctgtc aagtgcatac cggcagagat ctcctccgtc
    17761 cctgtccgac atctggtaga gttcgatgac ggcctgcagt cgcatctggt ttagatggat
    17821 ctcctcctcg gcacgcttct tctggacggc ctgcacaatc acgttgcgca gttcggcgaa
    17881 ctgggacttg ggatcccctc ccttctggag gtaaaacgag gctcccaggt tcagtgcctc
    17941 tattgccacg aactcccgcc cgcgccccgt gaagatgatg aaagggatat cgtatccaag
    18001 gttcttgaca gccttcagga gatcaagacc ggtcatctgg ggcatctcgt agtccgcgac
    18061 gatgatatcg aacttccgga ctgccagttt ttccagggca tcctttgcag actccgaaag
    18121 ggtcaccttc atcttcccgt ccctctcgag gaatatctgg gtaatgtcaa ggaggggagg
    18181 ctcgtcatcg acaagaagta cggatatcat gagaaatgca ccggattacc ctgaaattct
    18241 gataaattta ggtacatgca gagcattaaa agtattcggg ttacgggtct ttccatcccg
    18301 tatccctttc tgcccttttc atggagaacc tgtatcttcg cggaccatca gggtcccttt
    18361 ccccctgttt gcgacatctc cgcggaatac tgccatccgg aacttttttc caccgaactc
    18421 gacctctgcc gatccgttgc gccggaacga cgggaggagc tcccccgggt cccccatgac
    18481 catgcacgtg ccgcctgtca tgttcccgca gggccgggaa cagttccccc tgatcacgag
    18541 ggtaccgccc cgcatctcca cgcccgggag gtctccgcag ttcccatgga tgatcacctc
    18601 gccgcccgag agatactcgg caacgaagtc cccggcattt cccatgacct cgatggtccc
    18661 tccccgcatg ccgcgttttt ccccgcggta accggcaccg cagtaatcgc ctgcggtccc
    18721 ctcgcagagg attcgcccgc cccgcatctc gcgcccgagc catgcatcgg cattgccacg
    18781 gatgatgatc tcccctgcac tcatgaagtt cccgcagtgc atcccgatat ctccctcgat
    18841 gatgatcctg ccggcgttca tgtactcgcc gacccgcttg atcctcccgg tatcgcccgt
    18901 caggatgatc tcgacctggt cgggagagac tgcggggccc tcgaccgtca cgaagaagag
    18961 gtcctcgagg tgccgctcgc ggttcccctc gtacacggta agatcgtttt tgcgaaggaa
    19021 gttctggggg atgatgcctt ctgcctcgat cgggacatgg ggctttttcc gtggccttgt
    19081 cttcaggatg accctcatag tgcagcctcg gtctctatgc agactccccg cgggaggtac
    19141 acgtcctgga ctgggtaatt ccggagccgg acggtgtaat actggtcgaa cttcctgatg
    19201 aactccgggt cagaccccat gtcatactca ggcgggacac gggaccgtgt ccatatcgtg
    19261 ctgtttgccc cctcgacaac gacgtccccg tcccgggcaa cgaccctgcc cctcttgatc
    19321 gtgtagaggg tgcgggaaaa cccggccatc acctgctggt aatcgacgga cgggtcaagg
    19381 ttatcgggct tcagcgggta gattgccacg tcagcctgtg ctcccggcga gaggtgtccc
    19441 ttcccaatcc gggtgatccc catggctttt gcctgtccgg cccgcgtcat caccgcgatg
    19501 tcgtaccagt cgagctcccg gtcgagggca aagaggggga catagtgttc cgtccgggga
    19561 tcgatctcct ttcgctcgtt ctcccgcatc ctccggctca tcaggagggc gatgatctcg
    19621 gggtacttca cgaagggtgc accgttcggg ttgtccgtcg agaggaggca ctgccaggga
    19681 tttttggcaa ggagagcaag ctcgaggccg attgcccaca taacgcagtt gacgaggctt
    19741 ttccggctgt aatagacagg gatgatgcct gacccggtct ccagctccac gtcgtggttg
    19801 ctccacttgt tgtggtggag catgtagagc ttgaactcca tcgggccgtc tgctgtcatc
    19861 gttgtcgtcc gcccgaacat aatctggccc atgtcgatga ccacctgggg cttgctgttg
    19921 agggaacggg caatctcctc tgatttcgag ctgatatctc tccatgtcgt cccgccatag
    19981 gaatggaact ggacgtgcgt gaggtacagg gtctggcgat cacctccggc cggcggggcc
    20041 aggtccatcg tctcgagggt ggtccggaag ttccccggga ccccgaggtt gttgcagtgg
    20101 aggtggacgg agtgcggcag tcgcaggatc tcgtttgcct ggatcatcgt ggaaatgatc
    20161 tcggcagggg tgacttcgaa gtgggggacc gggtcgtgga tatgggacac gtccttgccc
    20221 cacccccatg cctcggtccc gcccgggttc gtcagcttga tggcaaagcc cttcacggcc
    20281 gcaagtgtcc aggcgacgat cgcggccgcc cttttgacgt ccttctccct gacagcctcc
    20341 atgacggacc agttcccgtc aaagagggtg ttggcaagca tgtcctggtg gggcgttgcc
    20401 gtgaactcct cgtgggtgtg ccgcgcctcg agcggggcca tagctccctc gagcaccgtc
    20461 gtgtatccca tcgtgctgta ccggtaggag tttccaaacg tcgtgggcac gctgtacccg
    20521 gacgtgacgt gcatgacgcc cttgcgggag gtgcggccgg ccctcatgtc ctcggggctc
    20581 atgtacctcc cgaagttaac cttcgtcccg cacacgtgcg agtgtgaatc gataccgccg
    20641 ggaagggtca ggcatccccc ggcatcgatg acctcggatc cgggaagggc atcctcgacg
    20701 atccggccgt cccggatggc aatatccatg atctcacccc tgatgccgga gagagggtcg
    20761 attacgtaag cgttctttat caggatcccc tgtgtcatcc ctttgcctcc ttcacgagcg
    20821 aatagatcct cccgaggaca gccacatcgt cggggtagcc ggtggaaaag agcttgcgcg
    20881 tcctgatcgg gacgccgtcc atgcggtacg cggtcccttc ggcatcgata ccggtcacgg
    20941 cgacgggtat ctggatcctt gagaggtggg tcgttgcgtt cacgtgggga tcgatctgga
    21001 ccgtggggat gcttgccagg tgctcggcac aggcacgcgg aaagtgcgca cccgggtcgc
    21061 ttgcaacaac gagacacgca tcgcattcct tccggcggag gaggtcaacg ctcgtcgtct
    21121 ccccggggtt gtaaaacgcg atcccccgcg agaaatcgac ggcatacgga tagcccgtaa
    21181 tccaggtgaa cacttcgttt gagccgtaca cgttccagtg acccctcatg ggagagatag
    21241 tgaacttcgt gtgtcggttg agttcctcgg tcagttcgat ggcgttgcgg atattcttgg
    21301 acttcccccg ggacatcgtc aggccgagtc cgaagaatat cgctccaaaa cgggcagaga
    21361 ggcagatctc ggctaccctg aagagttgtt ccctggttac cccgctgacc gtggcaggga
    21421 cgagatcacc tttcccccgc acgatcatgc gcagcgcagt gagaaccgcg tagtcacccc
    21481 ccggcgtcac tttcacgaac tcgtcggcga tctcggacga gtcggtctcg cggatatcca
    21541 cgacgatcac cttgcggtcc cggaacgcgg atttcacgaa gaacccgtcg gtaaaggtcg
    21601 tgtacctgct catgtgccgc gggtgtgcct cgatggggtt tgctccccag tatacgatca
    21661 cgtcggctcg gttcttgacc tggccgagcg tgcaacccgg gtgaccgacc tcctgtattg
    21721 ccaagatgga ggggccgtgg cagacggtcg aggtgttgtc gatgactgcg ccgaggagct
    21781 cggccatgtg gacacccagc gtctgggcct cgacgaacgt cccgctccac ccgtagagca
    21841 ggggccgctc cgcatcgagc aggatctctg ccgtctccct gatggcgtcg tcgtatgtgg
    21901 tcttctccca ggcgccgccc gtccgccgga tgggatgggc gagcctgtgg tcgccggtga
    21961 atttctctgt cgccagggtg cacccgttct cgaccgagag gacctttgtc ccttccacgg
    22021 agacgacgag gtcatcgcag aggcacccgc aaaaggggca gacgacgtcc tcaatcctca
    22081 tagggcatcc ccccgcactc cctcatcagg gcggagaccg ggagcggttg ctcggtcgtc
    22141 ggctcgatgc tgaccggcac ggtcttgaag tccggcatcc ccgtcccgtg cgtccacggg
    22201 ctggcaaggg cattcgcata cggcccgagg cagacgaaga cgagtccccg cgggagcatc
    22261 gggtcctgtc ttacccgcat gaccacggaa cccccggcac ctgtcacgcg tacggcatct
    22321 ccctcctcga cgaggagatc gaacatgtca acgggattca tgcggataca ggatgcctca
    22381 tcccggtaag gcgcggtatt cttcctctcg acataagagc cctgacggat cgtccttccg
    22441 gtcgtcatca ggaagttcat ggcacctcct ccggcgcatg gactgcttcc agcagccggg
    22501 cgacagaaat ggcttcgttc gggcagtggt gctcgcatgt tttgcatccc gtgcacttct
    22561 ccacgtggag gacgcggcac ttcccgtcgc ttaacttcag gaggagatca tcggtcgatg
    22621 cccggccgcc gtgcgacatc tgggcatcga tcagcttgtt gacagggcag gctaccgcac
    22681 agttcccgca ccccatgcac ttgtccaggt cgacgtctat tttgaaggag aaggagaggc
    22741 gggtattgtc acggaacatg gattccagga tcctgccgct cgagagcact ccgttggggc
    22801 aggcctcgac gcagagaccg cagcggatgc agtggccgat gtggatccgg ggctgccacc
    22861 cttcaggtgt cctgatgaca tcgatggcgc cgggggcagg gcaggccatc atgcagaaga
    22921 ggtgatgggt gcaggtcttg ccggtcagtt ccgggtaatt gcggaagtag ggagggataa
    22981 ccagcggagc tgtccgtgcc gcaagaaact ttcttgccca ttcccaccgg gcgaattccc
    23041 tgatatatgc gacgagggat atggccattg tcaccgctcc gtgcaggcta tgcaggggtc
    23101 agaggagacg aacgtggacg tcacgtccgc cagcgaactg actcctttca gcatgtaatg
    23161 gcagcaggcc tcgatgttca tgatcgatgg agtctggatg gagatctcga gcaccctccc
    23221 ggccgaatcc gttttaacga agtacgaaag ttccccgcgg ggagcttccc ccgagtacgc
    23281 gatctcccct gcacccggaa taccccctcc ccggatcggt ccttccggaa gctcgtccag
    23341 gcattttcga atcagcccga tactctggac aatctcctgg aaccggacca tgatgcgggc
    23401 gtagttgtcc ccctctgtcc tgacaacggg agaaaatccg aggctctggt aggtggggtg
    23461 gcgcaggcgc ctgtcgatat cgccaagacc gctggccctt gccgtcgggc ccaccgcgta
    23521 agcttcgcgt gccgcctctt tcgtgaggat cccgatcccc ttactccgga gggcgataag
    23581 gggcccactg gagaacatgt cggtataccg cgtgatctcc tgctcgatgg cagaaagtga
    23641 ctggcggagg gcctgtgcgt cttcggggcg gaggtcgaac cgcacgcctc ccgggacaat
    23701 ataggcgcag gtgacacggg cccccgtgat ccgttcgagc tggtccatca ccttctcccg
    23761 gacgtcgagg aggtacatcg ccagggtctc gtgctcgatg gtgtagcaat aggagaagtt
    23821 ggcaaggatg tggctctgca tcctgtcgag ctcgttgacg atgacccgca ggagtgcggc
    23881 acgccgggga acttcgatac cgctgatgtg ctcgagggcc tcgatgaaga ccatgttatg
    23941 gataaccgag cagataccgc agacacgctc ggcaaggaac atcacctcct gccatggcct
    24001 gcccttcatg atccgctcga tccccttttt catatatcca agttccacct cggccgagac
    24061 cacgtactcc ccgcgggtct cgcatttcac cctggcaggt tccttccagc aggggtggac
    24121 cgggccgacg gggatggaaa catcgacggt ccgcttcatt ttgttttcac ctcgtagtct
    24181 gcgaaaatgg ccggtgccac tgaaaggatg gcagagagta tctccgttgg acgcggcggg
    24241 catccgggca cctgcgcagc gatgggaata tgttttgcca ccggggggtc gacaagagta
    24301 tgggggcggg caaagaggca cccggatatc gggcagttcc cgatggcgat agcggccttc
    24361 gggggcggga tcttctccca gagcccccgg agtttctcct cccatccggg cgtgtacgcg
    24421 ccgatgacga ggaggatgtc tgcttcccgc gggttattgt ggacgaaaat cccgtactgc
    24481 tcgatgtcgt accgcggcga gaggcaggcg agcacttcga tgtcgcatcc gttgcacgat
    24541 ccgacgtcca cgtaggcaac gtggatcgaa cgcgaccgga cgaagttctt gaccttctgg
    24601 aggaacgtca tcggaggatc acctgccgga tcattgcctt tccggctgac actgcctcgg
    24661 aaaggggaat tcccgccgca atcctgtcct ttgtggcggt gacaatagta tccatcaccc
    24721 gctcgtcgac gagcgggaca gcccgggtat agaggtggga ggagagtgcc ctctcgacct
    24781 cgggcaggcc ctgctggaac tttttcccct gttcgtaccg ggcaggcagg ttctcgagga
    24841 ggagcatgtc gaggttctcc atcaggtatc gccggagcag gaggtggggg atgccaaggt
    24901 cggctgcaat ctcgcggacc atccggtcgt ggcgcctgct ctcgaggatg gcgtacttca
    24961 atgctgtcag gtctttttca tagagagcct ctttcatacc agtcctccca gccgtgcgag
    25021 gccgtaaaca aggaagagga gcacggcagc ccagagtgct gccttctccc agcggtccag
    25081 tataatcctg tcgcggaacc agtacatcgc cacagctgct gcaagggcgg ccccgatgag
    25141 aaacccctcc agccagaggg aaggacggtt ccatacctgg acggctatga ccaggatata
    25201 gatcaggaat gctgccacca aaacaactcg tatcatggca tcaccaccag gatgctgacg
    25261 taggcgagca tcaggcctgc aatgatcgtc tggactgtca cgctgtcgta cggcgagagc
    25321 atggggcaga gtgcacacgc aaatgagagc gacacggtga ggaccagcat gccgaggagc
    25381 aggaggagaa acggcaaaga ccccacgaag accagcagga acgtggtgag caggacgtac
    25441 gtctttaacc cgttgcagac ctcgaggcct gcccgccaga caccgaagtg ctcggtcttg
    25501 tacccgctga ccagttcctt gctctcgacg atggagaacg ggccaaaagg catcttggag
    25561 aggacgacga ggtacattgc caggccggcg aggggcaccg tgaggaggag cggcccgtgc
    25621 acctcctggt acgcgacgat gtctgatatc atgagggaac gggtgaagag tccaatcgcc
    25681 gccacactca cgaagagggg gatctcggac gcggccgaga tgacagaccg gacaccgccg
    25741 aacttcccgt agggtgaccc ggatgagagc ccaaacccgt gttccacgat cttgtggagc
    25801 atgtagacgg caaagatgat gaggaggctc ccacccgaga ggacgacgaa aagcgcggct
    25861 gtccatattc cgatcgcgac caggaccacc ccgacgaaga gggtagcact cgcagtcgca
    25921 gggacccacg tcgtcttgaa ggagaacttg agcatgtgca ggatctcctg ccagacgggg
    25981 ggccccggtc tcctctggat gcgtgcaatg accttccggt ggatacccag caggaggagc
    26041 ccgaagaccg tcccgaagag gagctcgcca atcattgcta gtaccccacg aacggtatgt
    26101 ccgggtctcc ttcccgggcc atccagtaca ggtacagtcc caggacgaag gccgggaacg
    26161 cgatgaccca ggctgcggca tctgcatggg gtggcagcac ccccgcgagg gtaaggaggg
    26221 ttgcagcgat ccctgccagg gcagatacca ctgccacggc gagtgcctgg gacttcttca
    26281 catgaggcgt cataggagga ggaccacctc cgtgacccgg aggaatatca ggagggacga
    26341 gagcgagcac atgatcacgt acggagcgcc gggtgcccgg aacatctctg cctttgccgc
    26401 gtagaaaggt gccatgccct ctcccatcac cccgaggaca aggagggcac gggcgatcag
    26461 tggaacggcc ggggccgctg gagacgccag ttcgagcatc gagagggtcc cggtcgttgc
    26521 ggcaacaatg gcagcggcag aaaagagggg aacagttccc gcgagggcga cgaggccgta
    26581 ctggtaggcg gcgtcctgga cgtggtaagt cctgaccgcg gcgacgatac cgacgttgca
    26641 gatcccgacg agcgagacga agagggtgaa atcgaagacg tctcccgtga ccattgcgcc
    26701 catgcacgcc aaaccgcagg caattgccat gaacctgcgg aaccggagct ccgggaggga
    26761 gatctccttg gcaaagaagg catccgcccc gaacgcgatg tcgatctgcc gttccgggcg
    26821 gctgacgatc acgaagaccg agaagacaag cgccaggagg aacagcgtga gcgtgaaggg
    26881 ggagaaatat gccacgatgt ccccgaactc gaggaagaag aggggaacgc cgccgatctc
    26941 gttcattccg cctcacccca catgactccc acgagcgaaa ttttcgtgat aaccttgagg
    27001 aggatgccga ccgcagctcc catcagcgcc aggaaccaga acgccggcgc gaacatgaag
    27061 acgaagaacg ctgcgaccca gagtgcccag gagatcccgc tcgcgagttc cagcacgtgg
    27121 aagtcgccga ggaacctgtg gctcatgaag tagaagacga ggccgagggc agcgatcccc
    27181 ccgcccgtga accccgagag gacgatcccg taaacgacga ggaaaccggg gatgatcacg
    27241 gttgcagggg acttttgcac gacctcgatg ttgagccccc ttgggggaac acctgcgagc
    27301 ccctccttgg cgatgtagag ctgcgagagg gcgaggagct cggcgatacc gacgacaagt
    27361 cccggcagga tgagtgcctc ggcaaggtcg gtcccgagga gtgcgatgac ggcgatcgag
    27421 gcgacctcca cgagatcgac gaggaggagc ttgtgcaggt catcgcgttc ccgtgcgagt
    27481 gccatgaatc caacaagggc agcgaggaag acgacgagga gaccgaatga gtactcattc
    27541 catgccatct cctagtcctc ccgcctgtgg aatatgtagg cagcgatggc aaacgagatg
    27601 aagaggattg tcggttcgac cacagtgtca agcccccgcg tgttgtagag gatttcgtcg
    27661 aggatgccgc ccgggtgtgc aacaatcgtc gtgcccatgt acatcgtggt ccgggaaagg
    27721 aagagcgaga agggggtgag gtatgcagtc acgtagcctg ccgttggcga attttgcggg
    27781 tactggagcc tgatgtcagc ctgcgtgaac ggcgggccgc ccctgtcata ggggttcagt
    27841 gtgctgcccg ggacgatctg cttgggatag agctggtcct cgaaataggg gaggggaaga
    27901 gagaggagtg caataacagc gaggattgca catgccccgg caaagagggg gagaatgttg
    27961 tcgtagttgg agaggacccg tgatattttc tggatgatca cgtttttccc tccctcttct
    28021 ggagaaccct gacgaagatg aagacactca gggcagaaac gccaccgtat gtcaaaaggg
    28081 cgagtgcctc gttatacgag agcatcacga ggagtattcc aatccccggg atctcgaggt
    28141 tgatcagcct gttcaggtag gtcttcggct ttggaaaggc agtccccact gtacctgcga
    28201 ggatgaggaa cagcccgatg aggaactcgg gggtcatggc tctccccccg ggcatgccat
    28261 caggatgaaa atggtcgaga ggggaaagat gagtgccacg gcaatggcca cgtcgaggag
    28321 tcccctgtcc acgatgaagg ggatggtccc gccgacgatg agcgagagcg ctatcagttt
    28381 ccggtacgga tcgctttccc ggatggcaag gacgcacccc agcacggcca gggctgcaag
    28441 tacgacgatg actgtttcat tcatccgcga tcgagacccc cggcatacgt gcttgcaatg
    28501 gcgtttgatt cgagcgtcga cccgacgaag taggccgcgg cagccacgat acccaggggg
    28561 tggggcagga ggagcgcgat gagacccgtg atcgcaaagg agagcacgtt gaggaaggga
    28621 agtttccgga gagtgtccgg ttcaagcgca acacgaacac ctgcgtacag ggcaactgtc
    28681 ccgcagagga ccagtgccat atcggctggt gtcatcccca cctcaccttc catatcgtgg
    28741 aaagaagcct gcttgcgtac acgtgggata ttccctggat ggacaggatt gcaatcacca
    28801 tcccggcgat gaactccgcg gcagagaacc cggcgagggt gaacccatag atgagaaagg
    28861 ttgccgtcag gcagcccgtc gtccctgcat atcccctgtc gtggcagatg cggttaccga
    28921 tgaagacgag gagtgctgcc agcagtccgc cggggatgcc tgcaatgaag actccgcagg
    28981 cagcaaggag agtgcctgca gatgcgtcgg gcgaggagac gatgttcccc atcatcgtgc
    29041 caccttccag cgatcctcca ccggcctcga tgtgccgggc gatggcagtg gccccgacaa
    29101 cccccccttt ttcggggagc ttgaagaaca tatctatcgt gataaaattg agccagcaga
    29161 cggctgctgc aaccaggata tgcacggtgg tcaggagaac ggtatccatc gggccgtcaa
    29221 cgtattaggg attagggctg aaggtgaata atattttgtt t
//
LOCUS       DAOOJU010000022        26437 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_1915_length_26437_cov_15.861762, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000022 DAOOJU010000000
VERSION     DAOOJU010000022.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 26437)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 26437)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26437
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1915_length_26437_cov_15.861762"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            111..926
                     /locus_tag="PK679_06550"
     CDS             111..926
                     /locus_tag="PK679_06550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC55649.1"
                     /translation="MTPANSEEYIHGHSRREALRLSDQANTLSSLLHHDTIYQPGSLV
                     LEAGCGVGAQTGILASRNTGTGIVSVDISIPSLRQARNAGIEGRWENVSFARADLFNL
                     PFPDEVFDHVFLCFVLEHLRNPSAALASVRRVLTKGGTLTVIEGDHGSTFFYPGSPHA
                     NDCIRCLEELQREMGGNPRIGRELYPLLSSAGFRNIHVSPRQVYVDGSRPDLACGFTR
                     QTFTAMVEGVRDQVLRREMMSPEDFDRGIRDLARAAGPEGVFCYTFFKAVCVK"
     gene            complement(1092..2138)
                     /locus_tag="PK679_06555"
     CDS             complement(1092..2138)
                     /locus_tag="PK679_06555"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55650.1"
                     /translation="MKMEHRGERRETGAYLDNPARDIEPGDHVAVIFRETSELAEVTE
                     MIRERCGKKRWSLLYIARFMEKNPAVEREQAMPGEEGCTWILSHDDPDFHRNFATAER
                     AYAYIRKKVEEAVKNGYSALCIMREVPPLSTRRSDQNLVSDLAELESLFQKGNIILIC
                     AYSLADSPPTVLQNVLRTHPLVVLDKKILENFFFIPASDAKRYNLPSLELQHWLDTLR
                     EISRRTEALRENEARYRDLLENASDLIQSVDAEGRFLFVNRTWRETLGYTHEDLRNMT
                     LFDVIDPVSLNHCRDLFQRVTSGEDVGKFEAVFRAKSGKKVYLEGRSNCLILGGRPRY
                     TRGIFRDITNKRTG"
     gene            complement(2231..3397)
                     /locus_tag="PK679_06560"
     CDS             complement(2231..3397)
                     /locus_tag="PK679_06560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-NAD kinase family protein"
                     /protein_id="HPC55651.1"
                     /translation="MNESNLFCPGGNRLFRIGFVVNPIAGMGGTVGLKGTDGLVEEAL
                     SRGAVPRAARRAEEAVRLLAGLPLRFLTCGGPMGEESLARAGISGYELVSNPPEGRTG
                     QEDTVEACRSFIGRGVDLILFCGGDGTARDIFSVVGDTIPILGIPAGVKMYSSVFAIT
                     PEAAATIIREGLEQGGRFHVRDAEVVDVDEEAYRRGEFATSLFGVARSLYRPGLSQMA
                     KQVYEDSDEERSKAEIARFIREVMEGTPDILYILGPGGTTSAVARELGVRKTLLGFDA
                     VKAGALVASDLDEKGICTLLARNPHARLVVSIIGAQGAIFGRGTQQVTPRILRTIGKE
                     NIIVIATPHKLLQTPNIFVDTGDSALDREFGDSIQVVTGYRVARRVRVTRCLQA"
     gene            complement(3426..4790)
                     /locus_tag="PK679_06565"
     CDS             complement(3426..4790)
                     /locus_tag="PK679_06565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrpB-like pyridoxal phosphate-dependent enzyme"
                     /protein_id="HPC55652.1"
                     /translation="MKTKILLDEDQMPRQWYNILPDLPSPLDPPLHPGTGKPLVPDDL
                     RPIFPMELIRQEMSDRKFIEIPSEVRDILLLWRPTPLFRAHRLEKHLGTPAHIYYKYE
                     GVSPPGSHKPNTAVAQAYYNMKEGIERIATETGAGQWGSALAFATQLFGLACTIYMVR
                     SSYAQKPYRKSMMQVWGAECIPSPSTRTKAGQAVLEKDPQTTGSLGIAISEAVEDAAT
                     HPDTNYSLGSVLNHVCLHQTVIGQECREQLASVDEYPDVVIGCVGGGSNFAGISFPFA
                     GDKLKGKRKDLDIIAVEPASCPTLTKGLYTYDYGDVAGLTPLLRMFTLGHDFVPPSIH
                     AGGLRYHGDSPIVSRLVHDGVMRAVSYHQSEVFDAAQTFARTEGIIVAPETSHAVKAA
                     IDEALACKRNGQTKTILFNCSGHGNFDMSAYDAYYAGQLVDYEYPDKLIREALSRIPR
                     VPGT"
     gene            5059..6366
                     /locus_tag="PK679_06570"
     CDS             5059..6366
                     /locus_tag="PK679_06570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55653.1"
                     /translation="MPGKTINFHGETFPAPVNDQWDFLLSTIWDQMIHLVITLGGSLD
                     EERLACAMRSVLATEPVLRSRFLDSRVPCWEELPALSTAAFFSLMRADDPEVTLRHVL
                     LQRIDPRSGPQARLTLIRGRKDTLVLSVNHTASDACGVRDTAVRIARFYRDYRGKSTL
                     ICPCIPPGDRSYAPIFSFFSPADRERARRACGDSSAEWGIPCIPGQCQSPCHTWKRIT
                     PDLFRRVRSLSRLEGLTINDLLLSAFFQSVSREIPHTDGRNYPVLTTVDLRRMVPGVP
                     APAVANLSVAFEVRLPADRSLSPLSHARETHRAMEEKKGNLAGLGAAIRLQERFEGGF
                     SRVRESLEDLARASRTEGYLKNPFFSNTGIIPPECTDFGDIKAVSAFLVPPVDYPPGF
                     SVAASTFGETLTLASGFCRDSVPAAVVEKVLQGIEDLLRTMVG"
     gene            complement(6425..6922)
                     /locus_tag="PK679_06575"
     CDS             complement(6425..6922)
                     /locus_tag="PK679_06575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HPC55654.1"
                     /translation="MRIGIMGDTHDHIPRIRKAVEALTREGVEIVLHTGDFIAPFVIP
                     EIAKVNVPVVGVFGNNDGDCPLLLARCREEGNMEIRGYFAELEYDGQKIALLHGHDRE
                     RLAGCMECGLYDLVVYGHTHRSAITRAGKSLCINPGEVCGYLTGDPGIALYTTGDRNA
                     RLIHL"
     gene            7007..7372
                     /locus_tag="PK679_06580"
     CDS             7007..7372
                     /locus_tag="PK679_06580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55655.1"
                     /translation="MTANKEGRDLVCGLESAIEGDDRVSRRKLLSRLVIFLSSTDTAA
                     PAFVSHGGIPLLLAATRDADEKIRIPALHTLTWLAKAGYGREILSAGGSAALDVLLAD
                     PYPQVRQMASGLKELLDRV"
     gene            7482..8912
                     /locus_tag="PK679_06585"
     CDS             7482..8912
                     /locus_tag="PK679_06585"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HPC55656.1"
                     /translation="MHMRIGGRDVAGADDRWMPVMNPATGEEIDRVPEGTLYEVDDAV
                     RAAEDAFPAWASRTARERGSILLRGASLVRERYGEISRLLTLEQGKPLRESADEIRGF
                     ANVLEYYAGIAGLFPGEYIPLGPAGDAIVTREPLGVCGAIIPWNMPALLMAWKTSPAL
                     LAGNTLVLKPASRTPLTDCVLARTLEEAGLPPGVLNVVTGKGEVVGEGIVRHPRISRV
                     SFTGNVETGLRVQELAAGSFKDVTLELGGSDPMIVWKDADIGNAVAGAVRGRFYNAGQ
                     TCTAVKRLFVHENISAEFLQRLRKRVEGLRVGNGLDEGIDMGPLCGPGQRDEINRFME
                     DFKRKGEGTILAGGEPLRGPAYDRGSFFAPTVVKDVHPESALLRKEVFGPILPVMCFD
                     DLDTAIRHANETRYGLGASIWTRDISVAREVFARVNAGVVWVNRHLTIPPEIPFGGVR
                     ASGLGRENGSQALLSYTRTKTLYIGR"
     gene            9089..9472
                     /locus_tag="PK679_06590"
     CDS             9089..9472
                     /locus_tag="PK679_06590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore germination protein GerW family protein"
                     /protein_id="HPC55657.1"
                     /translation="MTGEQMLKLCADELDRLLSPAHVIGDTVDLGDKAVIAVTEFGFG
                     FGAGGGKGKEGEGEGSGAGGKIAPVALVLVYKDIRGPDGIQVLSLHRDNPVAQIITAL
                     SESLAPQVIKAIKAMSESKMPETKE"
     gene            9493..10152
                     /locus_tag="PK679_06595"
     CDS             9493..10152
                     /locus_tag="PK679_06595"
                     /inference="COORDINATES: protein motif:HMM:NF022615.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HPC55658.1"
                     /translation="METSPSLSALVIILATALLGLGICAVPLRIRALVEFDGSGSRGF
                     FSVTWLGMGIRRRFPSQEGDLSVVALGVPVRSPFGHFATRRPIKSPVLGTRGGPSLLR
                     LVSGVLSHLPESIDIFRRIARSFSIRHLRCKAEIGLGSPAETGIFYGYFWAAKSIICA
                     IAPSVSIVVTPDFSRNRFEGEIDAEVMVRYPFMLPVYAIRVIEKTGIFSRPSRGGRVE
                     S"
     gene            10149..10421
                     /locus_tag="PK679_06600"
     CDS             10149..10421
                     /locus_tag="PK679_06600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55659.1"
                     /translation="MTFSSTYRAGPAIRIGDRSFFVVSRQTAARWESGCTGALSPVAL
                     VVLEDGMVSVYGLNPAIAEREVSRIVRDAFSPVPDSQFSLPEDYHT"
     gene            complement(10452..11618)
                     /locus_tag="PK679_06605"
     CDS             complement(10452..11618)
                     /locus_tag="PK679_06605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HPC55660.1"
                     /translation="MQTTLFFEFAKRNVRLHWLRSLLAIIGIIIGVTAIVSMGILGNS
                     LVLAISDSLSTVGDSVIVTPHVGGGSFSMGSASERITERQLEQIKRAVAPDITIPVYS
                     GSARMKVGTKDTAGVVYGLRPDDIPVLLEVEQGSYLRGSSGAMAGARFAKENDLRVGS
                     RITIKDKGTLRVVGILKERGMGFDINPDYGIVVEDKWYEQAYGQKDYDMVIVKVRDIS
                     RIEETKKVIEKQLNRRETVVDVIDTKAILETILDTFGRISTFTTAIGGISLIVAGVSI
                     LNIMMMSVTERIREIGVLRSIGTLRKEVMSMFLFEALILGIIGSLIGGVLSIIGGYAV
                     SLLMLRTSEYLFVPSSMVYVLYGVAFGIGTSLLSGLYPAWKASNLNPIEALRHE"
     gene            complement(11690..12379)
                     /locus_tag="PK679_06610"
     CDS             complement(11690..12379)
                     /locus_tag="PK679_06610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC55661.1"
                     /translation="MNGSPEHDPVIVFRDVVKIYPLPAGDVVALDHVSITVEPGEFIA
                     IMGPSGSGKSTLLNLMGCLDTPTSGYLEIKDRDIGSMNDDELTMLRRDHIGFIFQQFN
                     LIPLLTALENVQYPLILKTGSRECTARCIDILRAMDLDPSLYTHKPAELSGGQQQRVA
                     IARALVNDPDILLADEPTGNLDTKTGSAIMELLRELNEKRKKTIIMVTHDPNVARYAH
                     RTIRIVDGRIT"
     gene            complement(12376..13527)
                     /locus_tag="PK679_06615"
     CDS             complement(12376..13527)
                     /locus_tag="PK679_06615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55662.1"
                     /translation="MTVYRVFPFLLAVLLLFLPAAAAEQSQVAAAQVMVTNVTLNPQV
                     FMVGDSGTITVEIINNGAQSVAIRRATLYDEKIRVESRAYETTMYLGAGNRMTFTFTV
                     SAPVPEGIYYPVFSLDFRDAGYLRYPVKLRVQDQPLTVAVLSRPDTFTDGKKEKVEIL
                     VGNPRDNAVSGVTVYPVGEGIDATPTRHFIGLLAPDKSQNVAFQITPGKSAVLEFHVD
                     YYNGINPHTETIRVPIDVGKSKVQAEPILSNLRVEWSGTYYTLTGDVTNAGLEPANAV
                     VITMGRGAVPQDPYRQYAIGTLQPDDFSGFEVTFTVDGDRTSVPVVITHKDADGNLYT
                     TTYPVDIPAKGTRKPAAGTEESPLPVIAGVIVACAAVIGGIVWYSWRKR"
     gene            complement(13532..14221)
                     /locus_tag="PK679_06620"
     CDS             complement(13532..14221)
                     /locus_tag="PK679_06620"
                     /inference="COORDINATES: protein motif:HMM:NF016764.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0031267 - small GTPase binding [Evidence
                     IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Yip1 family protein"
                     /protein_id="HPC55663.1"
                     /translation="MNHVADLLFAPARFFSALEGKEPGLGIPALIAGIGAVISALAAY
                     AISDLYAGMFAAAGTGMDMGMFMGLMGAAGAFIGFILLWWIVLAGAFHVVSVPLRGKG
                     SFSGTLAATGYGLVPSVIGSALSAVTLLSYLPRITVPVIRNIQDPAVIQAAITEMMQD
                     PAMQEYTMVSTAFTVIFLVWSANIWIFGMKWARKLDTRNACITVLVPVGIFIIYLLAT
                     FFAKGFFMGGS"
     gene            complement(14573..15505)
                     /locus_tag="PK679_06625"
     CDS             complement(14573..15505)
                     /locus_tag="PK679_06625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HPC55664.1"
                     /translation="MRTIYRGTREGLEQIDTYESGAWINLVNPTPDEIREIVSWFQIP
                     PDFLTDPLDIDERARVEREEGSTLIVLRIPHRESPGADIPYTTIPLGIILTQNVTITV
                     CLTAADLIDEFLSGKVKHFSPDKQSRFILLLFYRNTLLYMRYLRDINRMTTQVERSLY
                     RALKNEQLIHLLNLEKSLVFFVTSLRSNALMMEKFHATGCVRMSEEDRDLFEDMIIEN
                     KQALEMANIYSSILSDMMDAFASVISNNLNVIMKLLTTVTIILMIPTLVASVYGMNVA
                     LPFQDTPYAFAFTMALSVAFSAIGILIFWRKELL"
     gene            complement(15699..16511)
                     /gene="budA"
                     /locus_tag="PK679_06630"
     CDS             complement(15699..16511)
                     /gene="budA"
                     /locus_tag="PK679_06630"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006113 - fermentation [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HPC55665.1"
                     /translation="MNEGRDRTLVILCVFCVAVIGIAGIWLAFPNGERQDRDVLFQVS
                     TIGALMEGNYRGVVPFGEIRKHGDFGIGTFDSLDGEMIAVNGEYFQVTADGAVLPVPD
                     GALTPFATVTFFEPDFTFFLSRADNFSDFSRQVERSLPSKDQIYAVRIPGKFPYVRAR
                     SVPRQEEPYPRLVDAARNQSVFILEGTRGTMAGLWFPEAFDGLNVPGFHIHYISDDRK
                     AGGHVLDFSLENATIEIDATPRFLVTLTPAGGNATGLSGPNSTELAGVEQGG"
     gene            complement(16567..16887)
                     /locus_tag="PK679_06635"
     CDS             complement(16567..16887)
                     /locus_tag="PK679_06635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HPC55666.1"
                     /translation="MEQNPMEVLLREAPDVAQAFDDLVDVFRTGDWTDAKTKQLLNIA
                     IQTAQRNPRGVFFHAGMARDAGARRREVVGAVVMNLHLSGLASVLDCLPAAVQGYERE
                     SGRI"
     gene            complement(16924..17343)
                     /locus_tag="PK679_06640"
     CDS             complement(16924..17343)
                     /locus_tag="PK679_06640"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: protein motif:HMM:NF013607.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase ArsC"
                     /protein_id="HPC55667.1"
                     /translation="MPTRVLFVCSRNAGRSQMAEGIARVLLPHCEVFSAGERPSEISP
                     VAIRVMAERGIDISSQYSKGVGDIPPGEFDVLVILGRWENPDRLPRARRVIQEILPDP
                     RDLSESRGEVEEGFRRVRDILWDRIGVWEKEGVFHVE"
     gene            complement(17392..17772)
                     /locus_tag="PK679_06645"
     CDS             complement(17392..17772)
                     /locus_tag="PK679_06645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HPC55668.1"
                     /translation="MFVRHVAGCTRERAGDGSLLCELVHPHRERNTIPFRASVAHAIV
                     PPGESTLPHRLRQSTEVYCIITGHGRMHIDGETGEVGEGDAVLIPPGAVQWLENTGTV
                     PLVFLAIVDPAWRKEDEEVFPPES"
     gene            complement(17934..19067)
                     /locus_tag="PK679_06650"
     CDS             complement(17934..19067)
                     /locus_tag="PK679_06650"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HPC55669.1"
                     /translation="MRELSRKLAGIPASATLEISNLARQMEKKGIPVISLSIGEPDFD
                     TPRHIKDACIRALLAGETHYAPSNGIPELLEAISSKISGENGFPCTPEEVIVTCGAKD
                     AIYDAMEAVLNPGEEVIILDPAWVSYEPCVMMAGGKPVHHPPDEKTFQIDDSVLERIS
                     PRTKMIVVNSPSNPSGAVLDKRSLSLVADMCTDFDLIALSDEIYEKLTYGKKHLSLAS
                     IGDMAGRTITVNGFSKAYAMTGWRLGYAVAPLPIIRNMAKVQQHSVSHPTTFAMYGGV
                     AALTSDQSCVEEMRAEFQRRRDYIVRELQMAGYRVAPADGAFYAFVRVEGDDVEVARR
                     WLEELHVAVTPGSAFHAPGWERLSYATSMENLEEAIRRICRAS"
     gene            complement(19064..19471)
                     /gene="ribH"
                     /locus_tag="PK679_06655"
     CDS             complement(19064..19471)
                     /gene="ribH"
                     /locus_tag="PK679_06655"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011842914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HPC55670.1"
                     /translation="MGIRLGFVVSEFNRDITYMMEVEAREHAAFLGAEVTECRYVPGA
                     YDMPLAVKRMLKEGKVDAVVTIGCVIEGATQHDEIVVQHAARKIIDLSLEFDKPVTLG
                     ISGPGMTRLEATERIDYARRAVESAVKMVQRLK"
     gene            complement(19533..19994)
                     /gene="ribC"
                     /locus_tag="PK679_06660"
     CDS             complement(19533..19994)
                     /gene="ribC"
                     /locus_tag="PK679_06660"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HPC55671.1"
                     /translation="MKIGVADTTFARVNMGNIAIDEIRKHASVPIERVTVPGIKDLPV
                     ACKKLIEERKCDIVIALGMPGGKEKDRMCAHEASLGLIACQLMTNTHIIEVFVHEDEA
                     SDDRELAWLAEMRTREHAVNAVRMVLRPADLVREAGTGQRQGFPDAGPARR"
     gene            complement(19991..21121)
                     /locus_tag="PK679_06665"
     CDS             complement(19991..21121)
                     /locus_tag="PK679_06665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HPC55672.1"
                     /translation="MEKEPLLMLPGPVPMPERVRAAMVRQAINHRGQEFSTVYADCVR
                     ILKEAFGTTNDLFVVSGSGTAAMEAAVGNFGRGKKIACLVNGKFGERLFKIAQRYGTA
                     TEIASPWGTPLDLGRLEEALAGGAEMVTLVHNETSAGIKNPARKVGSLCRKYDALFVM
                     DGITSVGGDEVSADEWGADVVVAGSQKCLAAPAGLSAISVSAKAWERMTEPRPFYLDL
                     AAYRKSATGKLMETPYTPAVPLFLALREACLILAEEGLSARIARHRRLADAVRAAAGA
                     WGVSLFPKIDADHAYSNTATAFSYPAGVDDSAFRGTIKKMGIEIAGGQDHLKGRIFRI
                     GTMGAIGAPEVLATLAAVQYALRKHGFVPKGDGVMAAAEVLG"
     gene            21180..21575
                     /gene="purE"
                     /locus_tag="PK679_06670"
     CDS             21180..21575
                     /gene="purE"
                     /locus_tag="PK679_06670"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HPC55673.1"
                     /translation="MVDVSILSGSASDASVVQKVADVLNEHSVSWEARVISAHREPDV
                     LDTYIRECQCKVFIAVAGLSAALPGVVASRTTRPVIGVPVSGKLMGGLDALLSIVQMP
                     RGVPVACVGVDNGENAALLAIRILSLLKE"
     gene            complement(21769..23049)
                     /gene="thiC"
                     /locus_tag="PK679_06675"
     CDS             complement(21769..23049)
                     /gene="thiC"
                     /locus_tag="PK679_06675"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HPC55674.1"
                     /translation="MSVMPSLIHECLSGLPELVEDVARKEGISPRIAARSVARGRLVI
                     PANPNRHHRTCGIGEGCRVKVNVNVGTSGPLCDLALEEAKARAALENGADTLMDLSTG
                     GDLRAIRRMLLSLDVPVGTVPVYEAVRRAGSAADVDADLLFSVIREHCRDGVDFLTLH
                     CGVNRDVLSALRTDPRIMPVVSRGGAFHVAMMVQRDEENPLYEEFDYLLEILSEYGVV
                     ASLGDGMRPGCLQDAERHAKTVEYLTLGRLAGRALEAGVQRMIEGPGHVPLPQVPCNV
                     QAIKELSNGAPLYLLGPIVTDLAPGYDHVVSAIGGAVAAMQGADFLCMVSPSEHLALP
                     NVDDIVEGTRVARIAAHIGDISRHREGYRAARELQMAEARQKLDWNAMFSLALFGDHA
                     RRIHERDGESETCSMCGDLCAVKLVREIFRRKGE"
     gene            23077..23679
                     /locus_tag="PK679_06680"
     CDS             23077..23679
                     /locus_tag="PK679_06680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011842908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC55675.1"
                     /translation="MPVRWIPGSGFLGNSYIVGHVLVDAGVLPTALERYRDTITEIVL
                     THCHFDHVAHLNEIARMCNARVSIHGLDAPGLSSDAESLSLHFGARAPMHPPDRILAD
                     GDRIGDLLVIHTPGHTPGSICLLHEAEHALISGDTVFSDGGFGRYDFPGGSRSALQKS
                     IGRLAGLTIEGLYPGHGSPVERGGSRHIQAARELLRLSYD"
     gene            23672..24109
                     /locus_tag="PK679_06685"
     CDS             23672..24109
                     /locus_tag="PK679_06685"
                     /inference="COORDINATES: protein motif:HMM:NF014088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HPC55676.1"
                     /translation="MIKGTYCLVLSSESCRVHVGALGELAFPGGYYVYVGSALGPGGL
                     SRVTRHIRLSKRPGSRPRWHIDYLLCSPSFSLETVYCFPTGERAECRLASLLSGIPIP
                     RFGCSDCRCHSHLFFYSTHPAAQIGKAAAILSLSVHSKTIKNP"
     gene            24125..24676
                     /locus_tag="PK679_06690"
     CDS             24125..24676
                     /locus_tag="PK679_06690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC55677.1"
                     /translation="MSVLGISGSMRKNGNTSRLIRAVLERCESAGIKTEFISLAGKEI
                     KPCLGCEKCKENDWCVIKNDDWSAIMEKVLECEVLVIGSPTYYYDVCGHLKNFIDRSY
                     SLYHRRQLAGRKAVAVAVCANKGGARTIETLEGFLNSHEFAYLGWVRGKGYLEGDIEK
                     DKRGLKRAREVGDKIVQLLKPSD"
     gene            complement(24754..25887)
                     /gene="cofH"
                     /locus_tag="PK679_06695"
     CDS             complement(24754..25887)
                     /gene="cofH"
                     /locus_tag="PK679_06695"
                     /EC_number="2.5.1.147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(D-ribitylamino)uracil--L-tyrosine
                     4-hydroxyphenyl transferase CofH"
                     /protein_id="HPC55678.1"
                     /translation="MSTDSMALSATLSGKELSTLLDDVLAGHRLTVGEAAGLFRVKGR
                     DVWRVAEAADEQRARTVGDTVTYVRNQNINVTNLCINSCGFCGFSRKPGDPDAYHHSA
                     DIVRKKAAEALARKVTEICTVSGLHPDFDAESYLRILSSIREGAPGVHIHASNPMEVA
                     YGAKKSGISTREMLSRMKDAGLGSLCGTAAEILADDVRKVICPGKIPSAEWERIIREA
                     HALGIRTTATIMYGHCETAEDRARHLGILRSIQDDTGGFTEFVPLSFIHYQTPLYRKG
                     IARAGATGREDLLMIAVSRLFFDNIPHIQVSWVKLGLKMAQIGLLAGGDDLGGTMFEE
                     SISKGAGASGTDYLDPAEMKRVVEDAGRVLRQRTTLYRILPGT"
     gene            25971..26273
                     /locus_tag="PK679_06700"
     CDS             25971..26273
                     /locus_tag="PK679_06700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YunC family protein"
                     /protein_id="HPC55679.1"
                     /translation="MQTERVPLRNSVGEGFVIPLGPVNLVGVVARNGMVGCGAVDVAA
                     LDRFGYPAARVRPSTGPSIATIGDLLAGIVKEANSNAQGLGVREGMTGREALDHLS"
BASE COUNT         5241 a         7912 c         7492 g         5792 t
ORIGIN      
        1 caagaacctg cctttacgtc aagtgaggcg ataccagtgc attcgacaat tcacttccga
       61 aatgaataat cgaaattcac atctcctacc aacctccatg aatactcaca atgacccccg
      121 caaactcgga agagtatatt cacggccact ccaggcgcga ggctctccgc ctctccgacc
      181 aggcgaacac cctgtcctcg ctgctccatc acgataccat ctaccagcca ggttcgcttg
      241 tcctcgaggc cgggtgcggc gttggggcac agacaggtat ccttgcatcg cggaataccg
      301 gaacagggat cgtctccgtt gatatttcga ttccatctct ccgccaggca cgaaatgccg
      361 gaatcgaggg acgatgggag aacgtctcct ttgcaagggc tgaccttttt aacctaccct
      421 ttccggatga ggtgttcgac catgtttttc tctgttttgt cctcgaacat ctccggaatc
      481 catccgctgc actcgcctcc gtgcgaagag tcctcacaaa gggcggaaca ctgactgtca
      541 tcgaaggaga ccatggatcc acctttttct atcccgggag cccgcatgcg aacgattgta
      601 tccgctgcct cgaggaactc cagagggaaa tggggggaaa tccccggatt ggccgggaac
      661 tctatcctct cctctcgtct gcaggattcc ggaacataca cgtctcgcca aggcaggtct
      721 acgtcgacgg gtcgcgaccg gacctggcgt gcggttttac aaggcagacg ttcactgcca
      781 tggtcgaggg tgtccgggat caggttcttc gacgggaaat gatgtctccc gaggactttg
      841 accggggcat acgtgacctc gccagggctg cagggccgga aggtgtcttc tgttacacat
      901 ttttcaaagc tgtctgtgtt aaataatgac cccgagggaa aaacagtccg gcatgattta
      961 tctccgggaa acacgggtca aaaatatatg tgatttcagg tgggtgaatc tcagaaacca
     1021 tgtggttatc caggagatac aaggatgcag aatgaaaacc ggaggccctc tttccagggt
     1081 gaccagactc actaccccgt tcttttatta gtgatatccc tgaaaatgcc gcgcgtatac
     1141 cggggcctgc ccccgaggat gaggcagttc gatctcccct cgaggtatac cttctttcct
     1201 gacttcgctc tgaacacggc ttcgaacttt ccgacatcct ccccggacgt cacccgctgg
     1261 aacagatccc tgcagtgatt gagggaaacc gggtcgatga catcaaagag ggtcatgttc
     1321 cggagatcct cgtgtgtata ccccagagtt tccctccacg tcctgttcac gaagaggaac
     1381 ctcccctccg catcgacgct ctggatgaga tcgcttgcat tttcgagaag atcgcggtaa
     1441 cgtgcttcgt tctcgcggag cgcctcggtc ctccgtgaga tctcccgcag cgtatccagc
     1501 cagtgctgca gttcgagcga ggggaggttg taccgttttg catcagatgc cgggatgaag
     1561 aaaaagttct cgaggatctt tttgtccaga acaacgagcg gatgtgtccg gaggacgttc
     1621 tggagtaccg ttggcggaga gtccgcgaga ctgtatgcac agatgaggat aatattccct
     1681 ttctggaaca gggattcgag ctcggcaagg tcgctcacta ggttctggtc agatcggcgg
     1741 gtcgagagag gtggaacctc gcgcatgatg cagagtgccg aatatccatt tttgacagcc
     1801 tcttccacct tcttccggat gtatgcatat gcacgttcag ctgttgcaaa attccggtgg
     1861 aaatcagggt catcgtgcga gaggatccac gtgcacccct cctcccccgg cattgcctgt
     1921 tctctttcaa ctgcagggtt cttttccatg aagcgggcaa tgtagaggag agaccacctc
     1981 ttttttccgc acctttcgcg gatcatctcc gtgacttccg caagttcgct ggtctctctg
     2041 aagatgaccg caacatggtc gccgggctcg atatcccttg ccggattgtc caggtacgcc
     2101 cctgtctctc tccgttctcc ccggtgttcc atcttcattt cctgcagtct gtcccattgg
     2161 agaagaaggt ttttccgggt caaatacttt gccgggagag gtcgaaggtc agttccggtg
     2221 attcgagggc tcaggcctgg aggcaccttg taacccttac cctgcgggcc accctgtaac
     2281 cggttacgac ctggatcgag tcgccgaact cgcggtcgag agcactgtca cccgtgtcaa
     2341 caaagatatt tggtgtctga aggagtttgt gcggggttgc aatgacgata atattctcct
     2401 ttccaatggt cctgagtatg cgtggagtca cctgctgggt ccccctcccg aagattgccc
     2461 cctgcgcccc gatgatgctc acgacgagcc ttgcatgggg attccgggca agcagtgtgc
     2521 agatgccctt ctcgtccagg tccgatgcaa cgagtgctcc tgccttcacg gcatcgaaac
     2581 cgaggagtgt cttcctgacg cccagttccc gcgcaacagc agatgtggtc ccgccagggc
     2641 caaggatata gagaatgtca ggtgtccctt ccatgacctc gcggatgaac cgggcaatct
     2701 ctgccttcga cctctcctcg tcagaatctt catagacctg ctttgccatc tgcgaaagac
     2761 cgggtctgta tagtgaccgt gcaacaccaa agaggctggt ggcaaattcg ccccgccggt
     2821 atgcctcttc gtcaacatcg acgacctctg catcccggac gtggaacctc ccaccctgtt
     2881 cgagcccttc cctgatgatc gttgctgcag cctccggcgt gattgcaaaa accgaggagt
     2941 acattttcac acccgcgggg atgcccagga tggggatggt gtccccgacg acagaaaaaa
     3001 tgtcacgggc tgtcccgtcg ccgccgcaga aaaggatgag atcaacccct ctcccgataa
     3061 aactcctgca cgcctcaacc gtgtcctcct gacccgtcct cccttcagga ggattggaga
     3121 caagctcgta gcctgaaatc ccggcgcggg ccagcgattc ctctcccatc gggcccccgc
     3181 atgtgaggaa acggagagga aggcccgcga ggagtcgtac tgcctcctcc gcccgccggg
     3241 ctgcacgggg gactgccccg cgggagagtg cttcctcaac cagaccgtct gttcccttca
     3301 gcccgacagt ccctcccatg ccggcgatgg gattgacaac aaacccgatt cggaatagcc
     3361 ggtttccacc gggacaaaaa agattggatt cgttcatgca gccgggatgc ttcgctcctc
     3421 tcttttcatg tcccggggac cctggggata cgggagagcg cctcccggat gagcttgtcc
     3481 ggatactcgt aatccacaag ctgtcctgca taatacgcat cgtaagcgga catatcgaaa
     3541 ttcccgtggc ccgagcagtt gaagaggatt gtctttgtct ggccattcct cttgcatgcg
     3601 agcgcctcgt caattgcagc cttcacggca tgcgatgtct cgggcgcgac aatgattccc
     3661 tctgtacggg caaaggtctg ggctgcatcg aagacctcgc tctggtggta cgagactgcc
     3721 ctcatgacac cgtcgtgcac caggcgcgaa acgatggggg agtctccgtg gtaccgcagt
     3781 ccgcccgcat ggatggatgg ggggacgaag tcatggccga gcgtgaacat cctgaggagg
     3841 ggggtgagac ctgccacatc cccgtagtca tacgtgtaaa gccccttcgt gagagtcggg
     3901 cacgatgccg gttccacggc gatgatgtcc agatcctttc tcttcccctt cagcttgtca
     3961 cccgcaaacg ggaaggagat ccctgcaaaa ttcgatcctc cacccacgca cccgattaca
     4021 acgtcagggt attcatcaac ggaggccagc tgttccctgc attcctggcc gattacggtc
     4081 tggtggaggc agacgtggtt caagacagat cccagggaat agttggtatc gggatgtgtc
     4141 gctgcatcct cgacagcctc ggatattgca ataccaaggc tccctgtcgt ctgcggatcc
     4201 ttttcgagca ccgcctgacc cgcctttgtc ctggtgctcg ggctcgggat acattcggcc
     4261 ccccagacct gcatcatgga cttgcggtag ggtttctggg cataactgga acggaccatg
     4321 tagatcgtgc aggcgagacc gaagagctgg gtcgcgaatg caagtgccga cccccactgg
     4381 cctgcaccgg tctcggtcgc gatccgctcg atcccttcct tcatgttgta gtatgcctgg
     4441 gctacagcgg tgttcggctt gtggcttccg ggagggctca ccccctcgta cttgtaatag
     4501 atgtgtgccg gtgtcccgag gtgtttttcg agccggtggg cacggaaaag gggggtcggt
     4561 ctccagagaa ggaggatatc cctgacctcg gagggaatct cgatgaattt ccgatcgctc
     4621 atctcctgcc ggatgagttc catcgggaaa atgggcctga ggtcatcggg gacgagcggt
     4681 tttccggtcc ccgggtggag cgggggatcg agtggcgaag ggaggtcagg aaggatgttg
     4741 taccattgcc gtggcatctg gtcttcgtca aggagaatct tcgttttcat aatgaataat
     4801 tgacctttgt ataaataaat acattgttgt acatttaagt ctggtgttga atattgtaat
     4861 acagtattct cccgggcaat tccccatgaa atacctcaag gcacccttcc gtcatgccgg
     4921 accatggtga aattgggtgg taaaaagcac ggaaatgtcc ggtggtcgca aaatcttttc
     4981 tcgtatccct ccgataatta ccgcctgcag cgtgcgggga gttccccgaa tccttttccc
     5041 ctctgcacgt ggaggagaat gcctggaaag accataaatt ttcacggaga gacgtttcct
     5101 gcccctgtca acgatcagtg ggacttcctc ctttccacca tatgggacca gatgatccac
     5161 ctcgtcatca ctcttggagg cagtctggac gaggaaaggc tcgcgtgtgc aatgcggtca
     5221 gtccttgcca ccgagcccgt gctccgctcc cgttttctcg attcccgtgt cccctgctgg
     5281 gaggaactcc ccgcgctttc cactgccgcg ttcttctccc tgatgcgcgc ggacgatccc
     5341 gaggtaaccc ttcgccatgt ccttctccag aggatcgatc cccggtccgg cccccaggcc
     5401 cggctcaccc tcatccgcgg cagaaaagat acactcgttc tttccgtcaa tcatacggca
     5461 tccgatgcct gcggagtcag ggacaccgca gtccgcatcg cccgctttta ccgggattac
     5521 cgggggaaga gtactctcat ttgcccctgc atccctcccg gtgaccggtc ctatgcaccg
     5581 atcttctcgt ttttttcccc ggcggacagg gagagagccc gcagggcatg cggcgactcc
     5641 tctgcggaat gggggatccc ctgcatcccc gggcaatgcc agtctccctg ccacacatgg
     5701 aaaaggataa cccctgacct gttccgaagg gttcgttcgc tttcccggtt agaaggactg
     5761 acgatcaacg acctcctgct ctccgcattc ttccagagcg tcagcaggga gatcccccac
     5821 accgatggga ggaattatcc tgtgctcacc accgtcgacc ttcgccgcat ggtgcccggc
     5881 gtgccggcac ccgctgttgc aaacctctcg gttgccttcg aggtccggct ccctgcagac
     5941 aggtcccttt ctccactctc ccatgcacgg gagacacatc gcgcgatgga agagaaaaag
     6001 gggaaccttg ctggtcttgg ggctgcgatc cgcctgcagg agcggttcga aggtggtttt
     6061 tcccgcgtcc gcgaatctct cgaagacctc gcaagggcca gcagaacgga ggggtacctc
     6121 aagaacccgt tcttttccaa taccggcatt atacctcctg aatgcactga ttttggcgat
     6181 ataaaagcag tatcggcttt cctggtacct cccgtggact atccccccgg tttctctgtt
     6241 gctgcaagca cttttgggga gacccttacc ctggcgtccg ggttctgcag agacagcgta
     6301 cctgcagccg tggtcgagaa ggtactccag ggcattgaag atctcctccg caccatggtg
     6361 ggctgaacgt ttcaggatag ggaacccttt cctgcaccag aggtttttcg caccggttgt
     6421 cccatcagag gtgaatgaga cgggcattcc ggtctccggt cgtgtagagg gcaatgcccg
     6481 ggtctcccgt caggtagccg cagacttccc cggggttgat acagaggctc tttccagccc
     6541 gggtaattgc gctcctgtgc gtatgcccgt ataccacgag gtcgtagagc ccgcattcca
     6601 tgcatccggc gagccgttcc ctgtcatgac catgcaggag tgcgattttc tggccatcat
     6661 actccagttc cgcaaagtaa ccccggatct ccatgtttcc ctcttcccgg cagcgggcaa
     6721 gaagcagggg gcagtcacca tcgttgttcc cgaatactcc cacgacaggc acatttacct
     6781 tcgctatctc ggggataacg aacggggcga tgaagtcgcc tgtgtggagg acaatttcga
     6841 cgccttcgcg ggtgagtgct tccacagcct tcctgatgcg ggggatatgg tcatgcgtgt
     6901 cccccatgat cccaatcctc attcttccct cctctccctt tataaccaga ctggcgccgg
     6961 gaataataaa aaaaccttat ttctccaggc agggaacaga tgggagatga ctgcaaacaa
     7021 agagggaagg gacctcgtct gcggtctcga gagtgcaatc gagggtgatg accgcgtatc
     7081 gaggcgaaaa ctcctctctc gtcttgtcat ttttctctct tcgacagaca ctgccgctcc
     7141 ggccttcgtc tcccacgggg gtatcccgct cctccttgct gctacgcgcg acgcggatga
     7201 aaagatacgt atcccggccc tccacaccct cacgtggctg gcgaaggcag gatatggacg
     7261 cgagatcctt tctgccgggg gcagtgccgc cctcgacgtg ttgctcgccg atccttaccc
     7321 gcaggtaagg cagatggcat cggggctgaa ggaattgctc gaccgggtct gacccggcgt
     7381 cgggcgactc tgtgggccgg gacagtcatt accggaagat tcctcatata tttggcgacc
     7441 gggatcaagt ataagaggtg tcaggtgtcg atccttgctt catgcacatg aggattggcg
     7501 gcagggatgt ggccggtgcc gacgaccggt ggatgccggt catgaacccg gccaccggag
     7561 aggagattga ccgtgtcccg gagggaactc tgtacgaggt cgatgatgcc gtcagggcag
     7621 ctgaagatgc atttccggcg tgggcttccc ggacggcacg cgaaagaggt tccatcctcc
     7681 tccggggcgc atctctcgtt cgggaacggt acggggagat ttcccgcctc ctgacgctgg
     7741 aacagggaaa acctctccgc gagtctgccg acgagatcag ggggtttgcc aacgttcttg
     7801 aatactacgc aggcattgcc ggtttgtttc cgggggaata catcccgctc gggccggctg
     7861 gcgatgccat tgtcacgcgg gagccactcg gggtctgcgg cgcgatcatc ccctggaaca
     7921 tgccagccct cctgatggca tggaagactt ctcccgccct ccttgccggc aacactctcg
     7981 tcctcaaacc agcctcaaga actcccctga cagactgcgt tctcgcacgt accctcgaag
     8041 aggccgggct gccccccggt gtcctcaacg tggtgacagg gaagggtgag gttgtaggtg
     8101 agggtatcgt gcgccacccc cggatcagca gggtctcctt caccggaaac gtagagacgg
     8161 gcctgcgcgt gcaggaactt gcagcaggct cttttaagga tgtgaccctg gagctcggag
     8221 ggtctgaccc gatgattgtc tggaaggacg ccgatatcgg gaatgccgtt gcgggagctg
     8281 tcagggggcg tttctacaat gccgggcaga cctgcaccgc cgtcaagcgc ctttttgtcc
     8341 atgaaaatat ctctgctgaa ttcctccaaa ggctgcggaa acgggtagaa ggactccgtg
     8401 ttggaaacgg tctcgatgaa gggatcgata tggggcccct ctgcggtccg gggcagcgcg
     8461 atgagatcaa caggttcatg gaagatttca aacgcaaggg agaggggacc atccttgcgg
     8521 ggggagaacc gctccgtggt cctgcctatg acaggggctc tttctttgca ccgacagtcg
     8581 tcaaagacgt gcatcccgag tctgcactcc tgaggaagga ggtttttggc cccatactcc
     8641 ccgtgatgtg ctttgatgac ctggatactg ctatccggca tgcaaatgag accaggtacg
     8701 gactcggtgc ctcgatctgg acaagggaca tttctgtcgc ccgcgaggtc tttgcccgcg
     8761 tgaatgccgg agtggtctgg gtgaaccgcc acctcaccat tccgcccgag ataccgtttg
     8821 gaggtgtcag ggcctcggga ctgggccgcg agaacggatc gcaggccctc ctctcctaca
     8881 cgaggacaaa gaccctctat atcgggcggt aggaagggag gaaaaactcc aaaagaccca
     8941 ctctttttcc attcatatca ggtaccctcc ccccggaaca cgtgttacct gtttttcaaa
     9001 atctcatgtg cagacaatat tcatggaact catgggagac tacttaacca ggcctgccac
     9061 atgactggtt caaggtgact acagacctat gacaggcgaa cagatgctca aattgtgtgc
     9121 tgacgagctg gaccggctcc tatcaccggc ccatgtcatc ggcgataccg ttgacctcgg
     9181 ggataaggcc gtcattgccg tgaccgaatt cggttttgga ttcggtgcag gaggcgggaa
     9241 gggaaaagag ggcgagggtg aagggagcgg agccggcggt aaaattgccc ctgtcgcact
     9301 cgtgctggtt tacaaggaca tcagggggcc cgacggcatc caggtgctct cgctgcaccg
     9361 cgataacccg gtggcccaga tcattacggc actctctgaa tcgctggccc cccaggtcat
     9421 aaaggccatc aaagccatgt cagagtcaaa aatgccggag acaaaagagt aaaaacggcc
     9481 gggtaatttc ccatggagac ctccccgtcc ctttccgcac tggtcatcat cctcgcaacc
     9541 gccctcctcg ggctcggcat ctgtgcagta ccccttcgca tcagggcact ggtcgagttc
     9601 gacggctccg gcagcagggg atttttctct gtcacatggc tgggcatggg gatcaggcgc
     9661 cgtttcccct cgcaggaggg ggatctctca gttgtcgccc tcggggtccc tgtccgatca
     9721 ccgtttgggc atttcgcaac ccggcgcccc ataaaaagcc cggtccttgg aacgaggggc
     9781 ggcccgtctc tcctccggct tgtgtcggga gtgctctccc atctcccgga atccattgac
     9841 atttttcgtc gcatcgcccg ttcattctcc atccgccacc tccgttgcaa agcggagatc
     9901 ggcctgggaa gccctgccga aaccggaatt ttctacggat atttctgggc ggcaaagtca
     9961 atcatctgtg ctattgctcc ctctgtctcc attgtggtga ctcctgattt ttcccggaac
    10021 cggttcgagg gagagatcga tgccgaggtg atggtacggt accctttcat gctccctgta
    10081 tatgcgatac gggtgattga gaaaacagga atcttttccc gtccatcccg gggagggaga
    10141 gttgaatcat gaccttttcc tccacatacc gggcaggccc tgcgattcgt atcggggacc
    10201 ggtcgttctt cgtcgtcagc aggcagaccg cagcacgatg ggaatcgggg tgcacggggg
    10261 ccttgtcacc tgtcgccctc gtggtgctcg aagatggcat ggtctcggta tatggactga
    10321 acccggcgat cgctgaaagg gaggtgtcgc ggattgtcag ggacgcattc agcccggtgc
    10381 cggattcaca gttttccctt ccagaggatt accatacatg aagaaccggg aggatttccc
    10441 cccgtgatcc ttcactcgtg ccgcagtgct tcgatcgggt tgaggttcga tgccttccag
    10501 gcaggataca gccccgagag gagactcgtg ccgattccaa acgccacacc gtaaaggacg
    10561 tagaccatac tcgacgggac gaagaggtac tccgatgtcc tgagcatcag gaggctgaca
    10621 gcatagccac cgatgatgct cagcacgccc ccgatcaggc tcccgatgat gccgaggatg
    10681 agggcctcga agaggaacat ggacatcact tctttccgga gcgtcccgat gctcctcaac
    10741 acccctattt ccctgatcct ttctgtcact gacatcatca tgatgttgag aatgctcaca
    10801 ccggccacga tcagggatat cccgcctatc gccgtggtga atgtggaaat ccgcccgaaa
    10861 gtgtccagga tcgtctcgag gattgccttt gtatcgatga cgtcgacaac tgtctcgcgg
    10921 cggttcagct gcttctcgat gaccttcttg gtctcctcga tccgggagat gtccctgacc
    10981 ttaacgatga ccatatcgta gtctttctgc ccgtatgcct gctcgtacca cttgtcctcg
    11041 acgacgatgc cgtagtcagg gttgatgtca aaacccatcc ccctctcctt gaggataccg
    11101 accacccgga gtgtgccctt gtccttgatg gtgatgcgcg agccgaccct gaggtcgttt
    11161 tcctttgcaa accgggcacc tgccattgcc cccgagcttc ccctgaggta tgatccctgt
    11221 tcgacttcga gcaggaccgg aatatcgtca ggacgcaggc cgtagaccac cccggcagtg
    11281 tcttttgtcc ccaccttcat ccgtgcgctg ccggaataga ccgggatcgt gatatcaggg
    11341 gcaacggccc tcttgatctg ttcaagctgc ctttccgtaa tgcgttcact cgccgagccc
    11401 atggaaaagg aaccgccgcc gacgtggggc gtcacgatga cgctgtcgcc caccgtggac
    11461 aggctgtccg agatggccag gacaaggctg tttccaagga tacccatcga gacgattgcc
    11521 gtcaccccga tgatgatccc gatgatggca aggagcgaac ggagccagtg aagcctcacg
    11581 ttccgttttg caaattcaaa gaacagggtg gtctgcattg tcccccttca cctgctcccg
    11641 ccctgcagag accggggtcg ctgacacgat tccccttcct gcctgcccct catgtgatcc
    11701 tcccgtccac gatcctgatc gtccggtggg catagcgggc aacgttcggg tcgtgcgtca
    11761 ccatgatgat ggtctttttc ctcttctcgt tcagttccct gaggagctcc atgattgccg
    11821 agcctgtctt cgtgtcgagg tttcccgtgg gttcgtctgc aaggaggatg tcaggatcgt
    11881 tgacaagagc cctggcaatt gccacgcgct gctgctgccc tccggagagc tcggcaggtt
    11941 tatgggtata cagggaggga tcgaggtcca ttgccctgag aatatcgata cagcgtgcgg
    12001 tgcattccct gcttcccgtc ttgaggatga gcgggtactg gacgttctcc agcgcagtga
    12061 ggagggggat gaggttgaac tgctgaaaga tgaaaccgat atggtccctg cgcagcattg
    12121 tcagttcatc gtcgttcatg gaaccaatat ccctgtcctt tatctcgagg taccccgagg
    12181 tgggagtgtc caggcagccc atgaggttga ggagcgttga cttgcccgat cccgacggcc
    12241 ccatgatggc aataaattcc cccggctcca ccgtgatgct gacgtggtcg agcgcgacaa
    12301 cgtcaccggc aggcaaaggg tagatcttga ccacgtcccg gaacacgatc acggggtcat
    12361 gctccgggga cccgttcatc tctttctcca ggaataccac actattcccc cgatgactgc
    12421 agcacaggcc acaatcactc ctgcgatcac cggcaggggc gactcctccg tgcctgctgc
    12481 aggtttccgg gttccttttg caggaatgtc gacagggtag gttgttgtgt agaggtttcc
    12541 gtcggcgtcc ttgtgggtga tgacgacggg caccgatgtc ctgtctccat cgacagtgaa
    12601 cgtgacctcg aaccctgaga agtcatccgg ttggagtgtc ccgatggcat actgcctgta
    12661 gggatcctgg ggaacggcac ctcgccccat cgtgataacg acggcgtttg caggttcaag
    12721 tcccgcattg gtgacatctc ctgtcagggt atagtacgtc cccgaccatt cgacccggag
    12781 gttggagagg atgggttctg cctggacctt gctctttccc acgtctatcg ggaccctgat
    12841 tgtctccgta tggggattga tcccgttgta atagtcgaca tggaactcaa gaaccgctga
    12901 cttgccggga gtgatctgga aagcgacatt ctgcgacttg tccggggcaa ggaggccgat
    12961 gaagtgccgg gtgggtgttg catcgatccc ttccccgaca ggatagaccg tgacccccga
    13021 aacagcgtta tccctggggt tccccacgag aatctccacc ttctccttct tcccgtccgt
    13081 gaaggtgtcg ggccttgaga gaactgcaac ggtgaggggc tgatcctgga cgcggagttt
    13141 cacgggatac cggagatatc cagcatcgcg gaaatcaagc gagaataccg ggtaataaat
    13201 accctccggg accggtgcgc tgactgtgaa cgtgaatgtc atcctgtttc ccgcgcccag
    13261 gtacatcgtt gtctcgtacg ccctcgactc gacccttatc ttctcatcgt agagcgttgc
    13321 cctccgtatc gccacgctct gtgccccgtt gttgatgatt tcaaccgtga ttgtcccgga
    13381 gtccccgacc atgaaaacct gggggttgag ggtgacgttc gtcaccatca cctgtgcggc
    13441 tgcgacctgg ctctgttcgg ctgcggctgc ggggagaaaa agcaaaagca ccgcgagcag
    13501 gaaaggaaag accctgtaaa cggtcatgct ctcaggaacc ccccatgaag aatccttttg
    13561 caaaaaatgt agcgaggagg taaatgataa aaatcccgac cgggacaagg acggtgatgc
    13621 atgcattccg ggtatcgagt ttccgggccc acttcatgcc aaaaatccag atgtttgcac
    13681 tccagacgag gaagatgacg gtgaatgcag tggaaaccat cgtatattcc tgcatggcgg
    13741 gatcctgcat catttccgtg attgcagcct ggatgacggc cgggtcctgg atattccgga
    13801 taacaggtac cgtaatcctg ggcaggtacg agagtaacgt aactgccgac agggcactcc
    13861 cgatgactga cggcacaagc ccgtaccccg tggcagccag ggtccctgaa aatgacccct
    13921 ttcccctgag ggggacggac accacatgaa acgccccggc caggacgatc caccagagca
    13981 ggatgaaacc gatgaacgca ccggctgccc ccatcagccc catgaacatt cccatgtcca
    14041 tccctgtgcc ggctgcggca aacatcccgg catacaggtc tgatattgca taggctgcca
    14101 gtgccgagat gactgctccg attcccgcta tcagggcagg gataccgagg cctggttcct
    14161 ttccttccag ggctgaaaaa aagcgtgcag gcgcaaaaag gaggtcagcg acgtgattca
    14221 tggtaataaa tctctcctcc cctgtatatg cactttccca cggggggtgc acccggggaa
    14281 aacggggact gggggaagag ttcctgtccg gcacccggtg atgatgattg gttcaccggt
    14341 agtgtccatt ttccatccac gggtttttcg gatggccccg tactggaccg ggaaggcttg
    14401 tttcccgagt gcctccccgc attgacggat taatgtccct atttgttatt tatttctaac
    14461 ataacgcaaa ccaatccccc ggtatgtgat tttggttatc tttctcgtga cattttccct
    14521 gctcccctgc aggtaaagcc tgttattctg gcggactgag ggaaccgggg tgttacagga
    14581 gttccttcct ccagaagatg agtatcccga tcgccgagaa ggcaaccgag agggccatcg
    14641 tgaaggcgaa tgcataaggc gtgtcctgga atggcaaagc gacattcatg ccgtagacgc
    14701 ttgcaacgag ggtcggtatc atgaggatga tggtgactgt cgttaagagc ttcatgatga
    14761 cgttgaggtt attcgaaatg accgatgcaa atgcatccat catatcggag aggatgctgc
    14821 tgtaaatgtt tgccatctcg agggcctgct tgttctcgat gatcatgtcc tcgaagagat
    14881 cgcggtcttc ctcgctcatc cggacgcacc ctgtggcatg aaacttttcc atcatgaggg
    14941 cattggagcg gagcgatgtg acgaaaaaga cgaggctctt ttccaggttc agcaggtgaa
    15001 tcagctgctc gttcttgagg gcacggtaga gcgatcgctc gacctgcgtc gtcatccggt
    15061 tgatgtccct caggtaacgc atgtagagga gggtattgcg gtaaaaaagg agcaggatga
    15121 accggctctg cttatcgggc gagaaatgtt tcacctttcc ggataaaaat tcgtcaatca
    15181 gatcggcagc tgtcaggcag acggtgatgg tcacgttctg ggtgagaatg atcccaaggg
    15241 gaattgttgt gtaggggata tctgcgccgg gagattcccg gtggggtata cgcaggacga
    15301 tgagggtgct cccctcttcc cgctcgacgc gggccctctc gtcgatatcg aggggatctg
    15361 tcaggaaatc gggcgggatc tggaaccagg agacaatctc ccggatttca tcgggtgtgg
    15421 gattgaccag gttgatccat gcaccactct cgtacgtgtc aatctgttcc agtccctccc
    15481 gagtaccacg gtatattgtc cgcatgatcc cgcaccacca tgtccgggcc gcaggagatt
    15541 gtccctgcca tcccgttttc cgggttggaa aaaccccttt tgcgtttctg ccggcgccac
    15601 tgcccgaata ggtctccttc tggtcgtttc tttcaaaaca caaaatatct ttcgatcatc
    15661 gcgtgaatag ggacaaaaaa gggaacatcc tggaaatatc agccaccctg ttccactccg
    15721 gccagttccg tgctgtttgg tccggatagt ccggttgcat tcccccctgc cggggtgagc
    15781 gtcacgagga atcgtggtgt agcgtcgatt tctatggttg cgttctcgag agagaagtcg
    15841 aggacatgcc ctcctgcctt cctgtcatcg gagatatagt gaatgtggaa accagggaca
    15901 ttcaatccat cgaatgcttc cgggaaccat aaccctgcca tcgtcccgcg ggttccttcg
    15961 agaatgaaca ccgactggtt cctggctgca tccacgaggc gcggataggg ttcctcctgc
    16021 cggggcacgc tccgggcccg tacgtatgga aattttcccg ggatcctgac ggcgtagatc
    16081 tggtctttcg acggcaggga tctttccacc tggcgggaga aatcagaaaa attgtccgcc
    16141 cgggaaagga aaaacgtaaa atcaggttca aagaaagtga ccgttgcaaa tggcgtcaat
    16201 gccccgtccg gaaccggcag gactgcgcca tcagcagtga cctggaaata ctccccattg
    16261 acggcgatca tttccccgtc gaggctatcg aaggtcccga ttccaaagtc cccgtgtttc
    16321 ctgatctccc cgaagggaac aactcccctg tagttgccct ccatgagtgc cccgatggtc
    16381 gagacctgga agagaacatc ccgatcctgc ctttcaccat ttggaaatgc aagccagatc
    16441 cccgcgatac cgatgacagc gacacagaac acgcagagga taacgagggt gcgatcccgc
    16501 ccctcattca tttctcttcc tcctgccctg cccccctcct gcttccacca gtcacattca
    16561 tccctgtcaa atcctgccac tttcccgttc atacccctgc accgctgcag gcaggcagtc
    16621 aaggacggac gcgagtccgg agaggtgaag attcatcacc accgccccga cgacttcccg
    16681 gcgccgggcg cccgcgtccc ttgccatgcc ggcgtggaaa aagaccccgc ggggattcct
    16741 ttgagcagtc tggatggcga tattgaggag ctgcttggtc tttgcgtctg tccagtcacc
    16801 cgttcggaaa acatcgacga ggtcgtcgaa tgcctgtgca acgtccggtg cttcccggag
    16861 aagaacctcc attggattct gttccataca ggataaaaga ggtcggcaac gagactaact
    16921 ttttcattcc acgtggaata ccccctcctt ctcccacacc ccgattcgat cccagaggat
    16981 gtcccgtacc ctcctgaaac cctcttcaac ctcgccccgg ctttcggaaa ggtcgcgggg
    17041 atcgggcagg atctcctgga tgaccctgcg cgcccttggg aggcggtcgg ggttctccca
    17101 gcggcccagg atgacgagca cgtcgaactc tccgggcggt atatccccta cacccttgga
    17161 atactgggat gagatatcga tgccccgctc cgccatgacc ctgatggcaa ccgggctgat
    17221 ttccgacggt cgttcgccgg cgctgaagac ctcgcagtgc gggagaagta ccctggctat
    17281 cccctctgcc atctgggagc gtcccgcgtt gcgcgaacag acaaagagga ctctcgtagg
    17341 catttcctga gaacccccgt tccgtgaacc ctcatccatg cccgaatcca atcaggattc
    17401 cgggggaaat acctcctcgt cttcctttct ccatgccggg tcgacgattg cgaggaacac
    17461 gaggggcaca gtccccgtgt tctccagcca ctggactgcc cccgggggaa tcaggactgc
    17521 gtcgccctcc cccacctcgc cggtctcgcc atcgatatgc atcctgccgt gaccggtgat
    17581 gatgcagtag acctctgttg actgccggag cctgtgcggg agggttgatt cccccggtgg
    17641 gacgatggca tgggcaacgc ttgcccggaa aggaatcgta ttcctttccc ggtggggatg
    17701 aaccagttcg cagagaagtg atccatcccc tgcacgctca cgcgtgcatc cggcaacatg
    17761 cctaacaaac atgcgggtac ctgcgcacga cccctcgata aaagcaccgt atcgttcctt
    17821 cccaaaatca cgggatttca ttcgcggttt tggggacccg atacgggtgg gcagccgtgg
    17881 tggaaaaaga ggcgggttgg tgaacggaac cttcggaatt ttattgagcg tgatcaggac
    17941 gcccggcaaa tccggcggat tgcttcttcg aggttctcca tcgatgtggc atacgagagc
    18001 cgctcccatc ccggcgcatg gaaggcggat ccgggtgtta ctgccacgtg cagctcctcg
    18061 agccaccggc gggcaacctc cacgtcgtct ccttcaaccc ggacgaacgc gtagaacgcc
    18121 ccgtctgccg gtgcgaccct gtatcccgcc atctggagtt ccctgacgat gtaatccctc
    18181 ctcctctgga attcggccct catctcctcg acacacgact gatcggaggt gagggcagca
    18241 acaccgccat acatggcaaa agtcgtcggg tggctgacgg agtgctgctg gacctttgcc
    18301 atgttccgga tgatgggaag gggtgcaaca gcgtatccga gcctccaccc cgtcattgca
    18361 tatgccttgg aaaaaccatt gaccgtgatc gtccgcccgg ccatatcacc gattgacgca
    18421 agcgacaggt gcttcttccc ataggtgagt ttctcgtaga tctcgtccga gagggcgatg
    18481 aggtcaaaat ctgtgcacat gtctgcgacg agggagagcg accttttgtc gaggaccgca
    18541 cccgatgggt ttgacggcga gttgaccacg atcatctttg tccggggaga aatcctctcg
    18601 aggacgctgt catcgatctg gaacgtcttt tcatcgggag gatggtggac gggttttccc
    18661 cccgccatca tgacgcacgg ctcgtacgag acccaggccg ggtcgaggat gatgacttcc
    18721 tcgccggggt tcagcacggc ctccatcgcg tcgtaaatcg catcctttgc gccgcaggtc
    18781 acgatgacct cttccggcgt gcagggaaat ccgttctccc ccgagatctt ggacgaaatc
    18841 gcctccagga gctccgggat gccgttgctc ggcgcatagt gggtctctcc tgcaaggagt
    18901 gccctgatgc acgcgtcctt gatatggcgc ggggtatcaa aatcgggttc accgatggag
    18961 agcgagatga ccgggatacc cttcttctcc atctgccggg cgaggttcga gatctcgagc
    19021 gtggctgagg cgggaatgcc tgcaagcttg cgggagagct ccctcatttc aatctctgga
    19081 ccatcttgac tgctgattcg accgctctcc tggcataatc gatgcgctcg gtcgcctcga
    19141 gccgcgtcat tccgggaccg gatatcccga gagtcacggg cttgtcgaac tcgagcgaga
    19201 ggtcgatgat ctttcgtgcc gcgtgctgga cgacgatctc gtcgtgttgc gttgcaccct
    19261 cgatcacgca cccgatggtg accacggcat ccaccttccc ctctttgagc atcctcttga
    19321 ccgcaagggg catgtcatac gccccgggaa cgtaccggca ctctgtcact tccgctccca
    19381 gaaaagctgc gtgttcccgt gcctccactt ccatcatgta ggtgatatcc cggttgaact
    19441 ccgagaccac aaaacccagg cggattccca ttctctcctc ctctaactat ctcgactctg
    19501 cagactgata accatatccc gtgcggggca ggtcagcggc gggccgggcc ggcatccgga
    19561 aacccctgcc tctgtcccgt tcctgcctcc ctgacaaggt ctgccggccg gagaaccatc
    19621 ctgacggcgt tgacggcatg ctcccgtgtc cgcatctcgg caagccacgc aagctccctg
    19681 tcgtccgatg cctcgtcctc gtgcacgaag acctcgataa tatgcgtgtt cgtcatgagc
    19741 tggcaggcga tcaggccgag agatgcctcg tgggcgcaca tccggtcttt ctccttcccg
    19801 ccgggcatcc cgagggcaat gacgatatcg cattttctct cctcgatcaa cttcttgcag
    19861 gcaaccggga ggtccttgat gcccggcacg gtcacccttt cgatcgggac actggcgtgc
    19921 ttgcggatct cgtcgatggc gatgttcccc atgttgacgc gggcaaacgt ggtgtcggcg
    19981 acccctatct tcatcccaga acctctgcgg cagccatgac gccgtcgccc ttcggcacga
    20041 agccatgctt cctgagcgca tactggactg cggcaagcgt tgcaaggact tcaggtgccc
    20101 cgatggcccc catcgtcccg atccggaata tcctgccctt gaggtgatcc tgcccccctg
    20161 caatctcgat tcccatcttt ttgattgtcc cgcggaacgc gctgtcgtcc acgcctgcag
    20221 ggtacgagaa cgccgtggct gtattggagt aggcgtggtc tgcgtcgatc ttcgggaaaa
    20281 gggatacccc ccatgcccct gcggcggccc tgacggcatc tgccagcctg cggtgccggg
    20341 caatacgtgc ggaaagacct tcttccgcga ggatcaggca ggcctccctg agggcgagga
    20401 agagtggtac tgccggggta tacggggtct ccatgagttt tccggttgca ctcttcctgt
    20461 acgcggcaag gtcaaggtaa aacgggcgcg gttcggtcat tctctcccac gcctttgcac
    20521 tcaccgagat tgcggagagt cctgcagggg cggcaaggca tttctgggat cctgccacaa
    20581 ccacgtcggc accccattcg tctgcactga cctcgtcacc cccgacggac gtgatgccgt
    20641 ccataacgaa gagtgcatcg tacttccggc agaggctgcc gaccttccgg gcagggttct
    20701 taataccggc agacgtctcg ttgtgcacga gggtgaccat ctctgcgccg cccgcgagtg
    20761 cctcttcgag gcgcccaaga tcaaggggtg tcccccacgg cgaggcaatt tctgtcgcag
    20821 tcccgtaccg ctgggcaatc ttgaagagcc gttccccgaa cttgccgttc acgaggcacg
    20881 caatcttctt tccccttcca aagttaccga ctgctgcctc cattgctgct gttcccgacc
    20941 cgctgaccac gaagaggtcg tttgtcgtcc cgaatgcctc cttgaggatc cgcacgcagt
    21001 cggcgtatac cgtcgagaac tcctgccccc ggtggttgat tgcctgccgc accatcgctg
    21061 ccctgacccg ttccggcatg ggtacaggcc ctggcagcat caggagaggt tctttttcca
    21121 taaaaaccag cccatagtat ttttacaacc gcggcatata agtgtggatg gcgaatgcca
    21181 tggttgacgt gtcgattctc agcggatcag catcggatgc atccgtcgtc cagaaggtcg
    21241 cggatgtcct gaacgaacat tccgtttcat gggaggcacg ggtcatctcg gcacacaggg
    21301 aaccggacgt cctcgataca tacatccgcg aatgtcaatg caaggttttc atcgcagttg
    21361 ccggactctc ggcagcgctc ccgggagtcg tggcctcccg gacaacacgc cctgtcatag
    21421 gagttccggt gagcgggaaa ctgatgggcg gcctcgatgc ccttctctcc attgtgcaga
    21481 tgcccagggg cgtcccggtt gcatgcgtcg gcgtggataa cggcgagaat gcagccctcc
    21541 tcgctatccg tatcctctct ctcctgaagg aatgatcccg caagggttgg tgcccgcgtg
    21601 gtctttcacg attgacagat ccggatatcc ttcctcattt ccccttccgg attcgaattg
    21661 cccggacttc agctcaaaaa gtgcattttt taccgtgagt aaaccggatg ccggagaatg
    21721 aattgctcca tcttgtggta ggaaagagga ggggaagtgc tctgcgactt actccccctt
    21781 cctcctgaat atctcccgga caagtttgac ggcgcagaga tccccgcaca tcgagcacgt
    21841 ttcagactcg ccatcacgct cgtggatcct gcgggcatgg tcgccaaaaa gggcaaggga
    21901 gaacatggcg ttccagtcaa gtttctggcg cgcctctgcc atctggagct cccgtgcagc
    21961 cctgtaccct tccctgtgcc tggaaatatc cccgatatgg gccgcaatac gggcaactct
    22021 cgtcccctcc acgatgtcat caacgttcgg cagggcgagg tgctcgctgg gggagaccat
    22081 gcagaggaag tctgccccct gcatcgcggc gactgctccc ccgatggcag aaacgacgtg
    22141 gtcgtatccc ggggcaaggt ccgtgacaat gggcccgagc aggtagagag gtgcaccgtt
    22201 ggagagctcc ttgatcgcct gaacattgca ggggacctgc gggaggggca cgtgacccgg
    22261 tccctcgatc atcctctgga cacctgcctc gagggcccgg ccggccagcc tcccgagggt
    22321 caggtactcg actgtctttg catgcctctc ggcgtcctgg aggcatccgg ggcgcatacc
    22381 gtccccgagg cttgccacga ctccgtactc cgagaggatc tcgaggaggt agtcaaattc
    22441 ttcgtagagc gggttttcct cgtcccgctg gaccatcatg gccacgtgga acgccccgcc
    22501 cctcgacaca acgggcatga tgcgggggtc ggtgcggagc gcggaaagga cgtcccggtt
    22561 gaccccgcag tggagagtga ggaaatcgac accgtcccgg cagtgttccc tgatcacgga
    22621 gaagaggagg tcggcatcga catcggccgc actccccgcg cggcgaacag cctcgtagac
    22681 agggaccgtg ccaaccggga catcgaggga gaggagcatc cggcggattg cccggaggtc
    22741 cccgcccgtg gaaaggtcca ttaaggtgtc cgcaccgttc tcgagggcgg cacgtgcctt
    22801 tgcctcctcg agcgcaaggt cacagagggg ccccgacgtc cccacgttga cgttgacctt
    22861 gacacggcag ccttcgccga taccgcaggt gcggtggtgc ctgttggggt ttgcagggat
    22921 taccagcctt ccccttgcaa cggaccgggc ggctatccgc gggctgatcc cctccttcct
    22981 tgccacatcc tccaccagtt cgggcagacc ggagaggcat tcatggatga ggctgggcat
    23041 aacagacatt gggtgggaga acctaattat tctaccatgc cggtccggtg gattccaggc
    23101 agcggcttcc tcggcaactc ctacatcgtc ggtcatgtcc tggtggatgc aggggttctt
    23161 cccactgccc tcgagagata cagggacacg atcacagaga tcgtccttac ccattgccat
    23221 ttcgaccatg tcgcccacct caacgagatt gcccggatgt gcaacgcccg tgtcagcatc
    23281 cacggactgg acgctcccgg tctctcgagc gatgcagaat ccctgtcgct tcatttcggt
    23341 gcacgtgccc cgatgcaccc gccggacagg atactcgccg acggggaccg catcggggat
    23401 ctccttgtca tccacacgcc gggtcacact ccgggaagca tctgcctcct gcacgaagcg
    23461 gagcatgccc tcatctcggg agataccgtc ttttcagacg gcggtttcgg gaggtacgat
    23521 ttccccggcg ggagccgatc cgccctccag aagtccatcg ggcggctcgc ggggctcacc
    23581 atcgagggcc tttacccggg gcatggatca cccgttgaac ggggagggag ccgccacatc
    23641 caggccgcac gggaactcct ccggctgtcg tatgattaag ggcacttact gcctcgtcct
    23701 ctcgtccgaa tcctgcagag tgcacgtggg tgcactgggg gaacttgcat ttcccggagg
    23761 gtattacgta tacgtcgggt cagcactggg gccgggggga ctctcccggg tcacccgcca
    23821 catacggctc tcgaagagac ccggatcccg gccacgctgg cacattgact acctcctctg
    23881 cagcccgtca ttttccctgg agaccgtgta ttgtttcccg acaggggaac gtgccgaatg
    23941 ccgcctggca tctctccttt caggcattcc catcccccgg ttcggctgca gcgactgcag
    24001 gtgccactcg cacctctttt tctattcaac ccatcctgct gcgcagattg gaaaagccgc
    24061 tgcaatactc tcgctatctg tccatagcaa aactatcaaa aacccataag gtgagtgtta
    24121 gtccatgagc gtgcttggaa tctctgggag catgaggaaa aacgggaata catcccgcct
    24181 gatcagggca gttctcgagc gctgcgagag tgccggcatc aagaccgagt tcatctcgct
    24241 tgccggaaaa gagataaaac cctgcctggg ctgcgagaag tgcaaggaaa acgactggtg
    24301 cgtcatcaaa aacgatgact ggagcgccat catggagaag gtcctcgaat gcgaggtcct
    24361 cgtcatcgga tcacccacgt actactacga tgtctgcggt cacctcaaga atttcatcga
    24421 caggagttat tccctgtacc acaggagaca actcgcggga aggaaagcgg ttgccgtcgc
    24481 ggtctgtgcc aacaagggag gtgcccgtac catcgagacg ctcgagggct tcctgaactc
    24541 gcacgagttt gcgtacctgg gctgggtcag gggcaagggg tacctcgaag gggacatcga
    24601 gaaggacaaa cgcggcctga aacgtgcccg ggaagtgggg gacaagatcg tccagcttct
    24661 caagccctcc gattgaaaat tatccctttt catccctgcc gggattcctg ccttttttct
    24721 ccccaaaacc tttagcgggg aatgataccc gcctcatgta ccgggcagga tcctataaag
    24781 cgtcgtccgc tggcgcagga cgcgtccggc atcctcgacg acccgtttca tctctgccgg
    24841 gtcgaggtaa tctgtgccac tcgccccggc gcccttggag atgctctctt cgaacatggt
    24901 gccgccgagg tcatcgccgc cggcaaggag gcctatctgg gccatcttga ggccgagctt
    24961 gacccaggat acctggatgt gggggatatt gtcgaaaaag aggcgggaga cggcaatcat
    25021 gaggaggtct tccctccccg tcgcccctgc ccgtgcgatg cctttccggt agaggggagt
    25081 ctggtaatgg atgaaactga gtgggacgaa ctcggtaaac ccccctgtat cgtcctggat
    25141 gctgcgcagg atgccgaggt gccgggcccg gtcttccgcg gtctcgcagt gcccgtacat
    25201 gatggtggcc gtagtccgga tgcccagggc gtgtgcttcc ctgatgatcc tctcccactc
    25261 cgcgctcggg atctttcccg ggcagatgac cttccgcacg tcatcggcaa ggatctcggc
    25321 ggccgtcccg cagagcgacc cgagccccgc gtctttcatc cgggacagca tctcgcgcgt
    25381 ggaaatacca ctcttcttcg ccccgtacgc aacttccata gggttacttg catggatgtg
    25441 aacaccgggg gccccctcgc ggatacttga aaggattcgg aggtaggact ctgcgtcgaa
    25501 gtccggatgc aggcctgaga cggtacatat ctcggtcacc ttccgtgcca gtgcttctgc
    25561 agcctttttc cgcacgatgt cggcagaatg gtggtaggca tcggggtcgc cgggtttccg
    25621 ggagaaaccg cagaatccgc aggaattgat acagaggttc gtgacattga tattctggtt
    25681 gcgcacgtat gtgacggtgt cgcccaccgt gcgggccctc tgttcgtcag cggcctctgc
    25741 gacgcgccag acgtccctcc ccttcaccct gaagaggcct gccgcctccc cgacagtgag
    25801 acggtgccct gcgagcacgt cgtcaaggag agtggagagc tcctttccgg agagtgtcgc
    25861 tgaaagggcc atgctatccg ttgacatgcg tcctctgaca gactgggagg actcactata
    25921 taaaacccgc ttccatgaca tttttagccc tgcccctcct ctcttaaaac atgcagacag
    25981 aacgcgttcc actccggaac tcggtcggtg aggggttcgt gatccccctc ggcccggtga
    26041 acctcgtcgg tgtcgtggca aggaacggta tggtcgggtg cggggcagtc gatgtcgctg
    26101 ccctggacag gttcggatat cctgctgccc gtgtcagacc ttccaccggt ccctccattg
    26161 caaccatcgg agacttgctg gcaggaattg tcaaggaagc gaacagcaat gcgcagggtc
    26221 tcggagtccg cgaggggatg accggcaggg aagcactcga ccacctctcg taaagatctc
    26281 ttctccagca cgcattactg gacccggaca ggaggcgttt cctcacctgt ttttaacgtt
    26341 tccctgtctt ttcatccctt ctgtgccggg gggacatttt cgcactggaa tcatccggaa
    26401 tggttgattt ttcccgggcg ggtgaagcgg cccgggg
//
LOCUS       DAOOJU010000023        25372 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2012_length_25372_cov_15.844018, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000023 DAOOJU010000000
VERSION     DAOOJU010000023.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 25372)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 25372)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25372
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2012_length_25372_cov_15.844018"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(196..1140)
                     /gene="mch"
                     /locus_tag="PK679_06705"
     CDS             complement(196..1140)
                     /gene="mch"
                     /locus_tag="PK679_06705"
                     /EC_number="3.5.4.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018759 - methenyltetrahydromethanopterin
                     cyclohydrolase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methenyltetrahydromethanopterin cyclohydrolase"
                     /protein_id="HPC55680.1"
                     /translation="MLSVNELALEIFENLAEYAEEFNATYHELDNGARIIDCGVSTRG
                     GYAAGRAFTEICMGGLGEVNFRMASIKDYPLPFIDVFTDFPSIACLGSQKAGWTIKHN
                     NYFAMGSGPARALSLKPKHTYEVIEYEDDFDSAVIALESDHLPNAQVMEKIAEDCHVD
                     VANVCAVVAPTSSIVGSIQVSGRCVETAVYKLNELHFDTRKITAAIGTAPVPPVRGPK
                     MAMGVTNDATIYHGRIMLTMKAPEIRDYLEKIPSNKSKGYGKPFNDIFKEAGYDFYKI
                     DTSLFSPAEVVINEISEGVVYHCGAVNPEVTLKSFGLL"
     gene            complement(1218..2342)
                     /locus_tag="PK679_06710"
     CDS             complement(1218..2342)
                     /locus_tag="PK679_06710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORC1-type DNA replication protein"
                     /protein_id="HPC55681.1"
                     /translation="MNKDILMWDETLFRDPEVFEIDYVPEQFNFRETQMRELAFQIKP
                     GMKGGRPLNTVCRGLPGTGKTTSIRKLFGEIEDTTKKLVPIHVNCQIDNTKFAVFSQI
                     YRKLSGHLPPSSGTSFKQVFDAIARILQKEEQVLLVALDDANYLLYENELNRVLYILL
                     RSHEAYPGTRIGVIVIISDMDVDLSRVLDARVSSVFRPTEIYFPPYTYEEVRTIIGER
                     VQQGLYMGCLSPELFELVVEQTQKSGDLRVGIDLLKRAGLNAEKRASRKIEREDICGA
                     YKVSRYLHLASSVKSLKPEERTVLGIIARHAEKGGEMNAGDVYQVVRQETELGYTRFY
                     EIIRKLDAMRLLNLEYRDGKGRTRMITLRYNPVKICEYIS"
     gene            complement(2392..2862)
                     /locus_tag="PK679_06715"
     CDS             complement(2392..2862)
                     /locus_tag="PK679_06715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55682.1"
                     /translation="MEGQRTLAIGITVNLENYENLRLEVNGPVKNEGDADELISFLDS
                     VLQKFGQGDPASKERVEAFRRRILPPGPERSKNETVVAQTQVAGGPAEPPPAVAQQVP
                     AQQVNAAKPSPADAGDAEGVPTCEECGVPVKPAEQKMSMLFASRTLCRKCLKNV"
     gene            complement(2985..4517)
                     /locus_tag="PK679_06720"
     CDS             complement(2985..4517)
                     /locus_tag="PK679_06720"
                     /EC_number="2.4.2.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ribofuranosylaminobenzene 5'-phosphate
                     synthase"
                     /protein_id="HPC55683.1"
                     /translation="MKEFFPCDDLERTAGPLSPLQRVLLGTDGSVTRILELACGAPVA
                     VTTRVQKVEKADPSVAENLQVQPGDEVNHRIVELKNTRTGETLIYAESYTPLSRLSSS
                     FRDDLMRADVPIGKILEHHRLETRREILGMSAGTRGPDIARAFGLSGNPLFLSRRYRI
                     IHGDFPLMHIEEVFPAASFTGERRVLVRAPSRIHLGLIDMNGSLGRVDGGIGLALGKP
                     EVVLSARRSEGFTVYGGDADARERVLAAAKSVAGALCLPGGAEFTIRSVYPGHVGLGR
                     GTQLALSTATALCHLYGQVQSPRDLARITGRGGTSGIGTATFATGGFICDAGHSLGDS
                     KDKTGFLPSSASRGVRPPEVILRHPFPVGWKILLAMPKSCIGASGTGEKDLFSSHCPV
                     PLDEVRELCHLVLVSLLPALVEEDLDLFGRAVNKMQGLGFKKIENMLAPPITQDLMET
                     MRDEGAAGAGLSSFGPVVFAFTEGDTGAIERACRKTLDRAGGGDIIRTTGCNAGAQVT
                     VT"
     gene            complement(4569..5741)
                     /locus_tag="PK679_06725"
     CDS             complement(4569..5741)
                     /locus_tag="PK679_06725"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cofactor-independent phosphoglycerate mutase"
                     /protein_id="HPC55684.1"
                     /translation="MKERKFVLILGDGMADEPLDELGGQTPLEYAQTPNMDRIAREGC
                     CGLLRTIPPGCEAGSDIANLSILGYDPRKYYTGRGPLEAASMGIDLAETEMAYRCNLV
                     TIRDGTMTDFSAGHITSAEGAALLSDLQKVISPVRIFPGVSYRNVLVLPDAKGAKTVP
                     PHDIVGQEIDRYLPDGKDAKVLRSCIEASGRVFDHHPVNSARISRGLAPATHIWPWSG
                     GKTPALTPFAEKYGISGGMISAVDLLRGIGRCARMEVINVPGATGYLDTDYQAKARYA
                     LDALRYLDFVYVHVEAPDEAGHLGSLVEKVRAIERVDAMIGTILDGCSACIAVLPDHP
                     TPLRIRTHSPDPVPFAILGGRKDGCKSFCEREAADGSSGVLEGTQFMPLFLTGTPG"
     gene            complement(5738..6205)
                     /locus_tag="PK679_06730"
     CDS             complement(5738..6205)
                     /locus_tag="PK679_06730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HPC55685.1"
                     /translation="MDIPAALTVVILGALPFFEARYAIPAAILYGFPPLTAFGLGIIG
                     NLLPVIPLLLLLDPVSGWLRVRSQTMDRFFSWLFERTGRHEEQIRRYGAPALFLFVAM
                     PIPVTGTWSGCAAAFVFRIRFREAFLAIAGGAFVAALITTLPLLGLMKLFGGA"
     gene            complement(6209..7138)
                     /locus_tag="PK679_06735"
     CDS             complement(6209..7138)
                     /locus_tag="PK679_06735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HPC55686.1"
                     /translation="MACVVTGGAGFIGSHLVDALVARGEAVRVIDSLRSGSEQNLSAH
                     LSRDRILFRKADLLEDGWQDFLSGAGRVWHLAADPDVRQGALTPESQVRQNILATWRV
                     LEAMRAAGVPEIVFTSTSTVYGDAKVIPTPEDYSPLEPVSVYGATKLSCEALISAYCH
                     SFGMKAWIFRFANIIGKRSNHGVIWDFIRKLSGNPHRLEILGDGRQSKSYLEVSACVD
                     AMLYAADHASGRVNTFNIGSEDWIDVRSIADLVVEEMGLSGVEYIFTGGERGWIGDVP
                     RMQLSVQKLKSLGWKPPLGSRESVRMAIAAMLE"
     gene            7181..8059
                     /locus_tag="PK679_06740"
     CDS             7181..8059
                     /locus_tag="PK679_06740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 12 protein"
                     /protein_id="HPC55687.1"
                     /translation="MFIGIDHGTSAMRFSGGPGHRFKMRREDAVSFEMEDLEEICPLD
                     EIEGIALSYSMGDNFSAITPVRKLSNRGLVSREGAGKHIGGGTRVFDRVAESSIPAVA
                     VPGLHRGSPTDPRFRVYSHQASPEKVGIALRVTQDLGRDVVISDISSNTVTLIVKDGR
                     LAGALDACIFAPGTEHGALDVDAIRKIDRGEISANQAFMSAGVNHTLPPEERLPALGL
                     FAAMECAALLVLAPHARVALSGSMAAAVAETVQSLLGREITVYDEWCAADGLSLIARE
                     VFSRGAGTILGLSVNR"
     gene            8118..8660
                     /locus_tag="PK679_06745"
     CDS             8118..8660
                     /locus_tag="PK679_06745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate ferredoxin oxidoreductase subunit
                     gamma"
                     /protein_id="HPC55688.1"
                     /translation="MRELRIHGRGGQGSVTAAELIAVAAFAGGVYSQAFPAFGVERRG
                     APVQAFVRFDDRKIRLRSQVYEPDYIIVQDSTLISDVNVFHGVKPGGVVIVNTEKPLA
                     AQVPPGVKVITLDATSIALKHLGVPITNTTLMGAFAAASGEIDFAALEEAIRGRFTGE
                     MAEKNVAAAREAYAIVKGVS"
     gene            8663..8923
                     /gene="porD"
                     /locus_tag="PK679_06750"
     CDS             8663..8923
                     /gene="porD"
                     /locus_tag="PK679_06750"
                     /EC_number="1.2.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate synthase subunit PorD"
                     /protein_id="HPC55689.1"
                     /translation="MTLGLGCSSRPGTSRVNRTGSWRTFRPVFLRDKCTKCRLCIQLC
                     PEGCIMEESEGFPVPDYDYCKGCGLCAEECPAEAIEMQKEEK"
     gene            8925..10082
                     /gene="porA"
                     /locus_tag="PK679_06755"
     CDS             8925..10082
                     /gene="porA"
                     /locus_tag="PK679_06755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate ferredoxin oxidoreductase"
                     /protein_id="HPC55690.1"
                     /translation="MMEIMEGSHAVAHAVRMCRPEVIAAYPITPQTHIVEALAEMVAN
                     CSLDAEYITVESEFSALSACLGASAAGSRVYSATTSQGLALMFEVCFNTAGLRLPVVM
                     SIVNRALGAPLSIWNDQQDSISLRDSGWLQFYAEDNQEATDLHYIAYRVAEDKSVLLP
                     AFVCLDGFILSHTYEPVEMLTQEQVDSYLPPYSPVQRLDSKNPISIGLFTSPDYYMEF
                     RYEMDRAMKASSQVIREAGRRFGEMFGRDYSNLVEEYRLDDAECAIVAMGSICGTVKD
                     AIDEMRGDGQKVGLLRIRTFRPFPGEEMKKALSGVSSVAVLDKNISLGAKGAVALEVR
                     DALYGSGIPILDYIIALGGRDVAKKDIKSVVKMAMAGKGDLFYGLRGEVLG"
     gene            10079..10972
                     /locus_tag="PK679_06760"
     CDS             10079..10972
                     /locus_tag="PK679_06760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HPC55691.1"
                     /translation="MKGEQCSLFDPGHRACGGCAAALAARAVLDAAGPDTIIVSATGC
                     MEVFSTPYPETAWKVPWIHSLFENNSAVASGITAALKKQGRKEKVIALGGDGATFDIG
                     MLCLSGAFERGHDFVYICYDNEAYMNTGIQRSGATPYDASTTTSPAGKCSTGNRRPKK
                     DLPAILAAHGAPYVATATVAYLPDLKKKVKKALDTEGPCYVQVHAPCCTGWGFEGEKT
                     LAIARLAVETGLFVSFEMENGVVTRVKKVVRKPVEEYLKEQRRFRHLFRPKRNDAEIA
                     KIQAIADGNAQKFGIDINLKK"
     gene            11028..11423
                     /locus_tag="PK679_06765"
     CDS             11028..11423
                     /locus_tag="PK679_06765"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55692.1"
                     /translation="MRNDATCGPRVLFMDDDEGIRDVVRVFLSGLGYRVEVVADGGSV
                     IESYRKAIEEGDPFRVVILDLTVSAGKGGIETLRELKSIDPEVKAVITTGFTDDPVFS
                     GFGAQGFVAAIPKPFHVRQLDETLRGILS"
     gene            complement(11430..12053)
                     /locus_tag="PK679_06770"
     CDS             complement(11430..12053)
                     /locus_tag="PK679_06770"
                     /inference="COORDINATES: protein motif:HMM:NF039237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5803 family protein"
                     /protein_id="HPC55693.1"
                     /translation="MQSTSGDRRGSSLVTLCIAVLLVILPCAASRADYHILPNGTAYS
                     ASLDLADATGYEFFEAGILGERVPVKVVDVALTGNCSPCTFSWRGENTILFPKGNYTL
                     TFQGPVRDNHFIAIYDRPRRVTIVLPAGFDVRNPALGMVSSGATVTDLPEGLTEISWN
                     TTRIAEIRFYEKGREDLLYLFANIWVVIAIVMLVPFLLTWRKDHISP"
     gene            complement(11984..13195)
                     /gene="thrC"
                     /locus_tag="PK679_06775"
     CDS             complement(11984..13195)
                     /gene="thrC"
                     /locus_tag="PK679_06775"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HPC55694.1"
                     /translation="MYRLVCVGCGKGYSPDEIIYNCTVCGHLLAVEYDLDSIMIEREV
                     WERRPLSVWRYRELLPVSIPPVTLQEGGTPLYHLTRIGEEIGVPNLYAKHEGMNPTGS
                     FKDRGMTVGVSMALQLKKTSVACASTGNTSASLAAYAARAGIPAVVLLPAGKVALGKV
                     AQALMHGARVLSIRGNFDRALELVHELCLSHGLYLLNSVNPFRLEGQKTIGFEVLDQL
                     GRSPDRMVLPVGNAGNISAVYKGFVELADLGLLNGMPMMTGIQAAGSAPVVRAIQQGL
                     AEVEPEPQPETVATAIRIGAPVNAEKALAAIRKTGGCAEAVTDDEILAMQRDLAQKEG
                     IGVEPASAASVAGVKKLIETGVIDRDETIVCVVTGHLLKDPETVIRQCKAPLEIDADL
                     PSLLSALQFCS"
     gene            complement(13288..14079)
                     /locus_tag="PK679_06780"
     CDS             complement(13288..14079)
                     /locus_tag="PK679_06780"
                     /inference="COORDINATES: protein motif:HMM:NF012993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="HPC55695.1"
                     /translation="MILCCAQIESSWEDPEATLARAERCIGRASRNGGDLVCFPEQFA
                     TGWDPSSLRHVQGLDGPLVGHLQSLAEEYSIAILGSLRKYSVPRPENTCIAISPQGKI
                     LAEYSKCHLFSPAGEDRVYQRGNAIAPFTLAGMTLGIAICYDLRFASIFALYADAGVD
                     AVLVPAAWPASRLSHWELFIRARAVEYQVYVAGINTTGVTPVDTYNGGTMVADPTGAP
                     LFIAGAGEGVYSCEMSREFVERVRNAFPVKKDRHPDIIQSDKTRP"
     gene            complement(14230..14679)
                     /gene="ndk"
                     /locus_tag="PK679_06785"
     CDS             complement(14230..14679)
                     /gene="ndk"
                     /locus_tag="PK679_06785"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006165 - nucleoside diphosphate
                     phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HPC55696.1"
                     /translation="MERTFVMVKPDGVARGLIGGIIQRFERKGLKLVAARFERIPEKR
                     VLEQYREHLEKPFFPSLRHFIESGPCFLMVWEGKNAVSVVRKMIGTTNPAEAEPGTIR
                     GDLALDTGRNVIHASDSPASAAREISLHFSPDEIITYKRTDEPSLYE"
     gene            complement(14686..14877)
                     /locus_tag="PK679_06790"
     CDS             complement(14686..14877)
                     /locus_tag="PK679_06790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24e"
                     /protein_id="HPC55697.1"
                     /translation="MVEQRNCSFCGDAIEPGTGKMFVRKDGSVFYFCSTKCQNNFRLG
                     RAPRRVSWTQAGRKAAGKE"
     gene            complement(14886..15095)
                     /locus_tag="PK679_06795"
     CDS             complement(14886..15095)
                     /locus_tag="PK679_06795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S28e"
                     /protein_id="HPC55698.1"
                     /translation="MADEGTPAEVIEVIGSTGMHGEAMQVKCRILDGPNKGRIITRNT
                     VGPIREGDVLMLLETEREAKKLSRR"
     gene            complement(15103..15471)
                     /gene="rpl7ae"
                     /locus_tag="PK679_06800"
     CDS             complement(15103..15471)
                     /gene="rpl7ae"
                     /locus_tag="PK679_06800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7Ae"
                     /protein_id="HPC55699.1"
                     /translation="MAKSYVKFQVSEEIQNKALEALEIARETGKIKKGSNEATKAIER
                     SIAALVLIGADVEPEEIVMHLPPLCEEKKIPFVFINKQNDIGTASGLDVGSAAAAIVK
                     PGKAKELVDEIVKQVSELRA"
     gene            complement(15610..17715)
                     /locus_tag="PK679_06805"
     CDS             complement(15610..17715)
                     /locus_tag="PK679_06805"
                     /inference="COORDINATES: protein motif:HMM:TIGR03662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2298 domain-containing protein"
                     /protein_id="HPC55700.1"
                     /translation="MSVLSWLLLLFFLQVSVWPYLRRAFAGYAYPVSFPVSFLLFSLI
                     SWYCGLFRLPVFLALVPFAALFLLAASRNGYSGRFWSAQWIYVATFLLFFFSMVSVRF
                     TNPSISYAEKFMDHAFLASVMRVPVVPPLDPWFSSGYLNVYYYLGYWMFGALGITSGV
                     PSQISFNLVLPTVFGFSAVLLYALGRMIAPRFPWMVPATLVIVNPSFILQVIQGKAAG
                     SVLWDSTRTITNTINEYPLFSFLWGDVHPHVIGIFNQVLFIFLLVYSLLRFKDLDVWG
                     RALLILICGLSLGSMPPINTWDIIVYAPVTLIFGFMIWRQAKKSPQYTGFWRGLTGYV
                     RRLVNSAKSGLQLRCAQCLGGIGRVPAIILEAHGSFFFLVPVTAVLCYLPFYLQMNTS
                     GILGVGLVHTPTAPVEFLLVHGFFILVMVLYVAHDIWKRPLFLIAPAVVALAGFPAAA
                     IATVPLVYLLAGKRQTPAEILAMLGLAIVIVCEFFYLKDNMGETYYRMNTVFKFYIPA
                     WLLMGASSFSMVSTMAARRVPPGYFPAWSGRLALAVVSVILIVTPLAVPLDPPYTGGT
                     LDGLAYLETAHPGDASAIAFLRSLPGVKGVVEAEGGDYTYFGRVSSFTGIPTIIGWPF
                     HEYMWRTDTNGWYGKRLSDVRTIYEDPEMTRELMKHYNMTHLYVGDLERERYNVRVEE
                     SGLVTVYNQNGVLIYALDG"
     gene            complement(17732..18697)
                     /locus_tag="PK679_06810"
     CDS             complement(17732..18697)
                     /locus_tag="PK679_06810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HPC55701.1"
                     /translation="MWKKASTIVISTLLAVGIVVFMLYTIWDDLLVAAEHAVWYFLVL
                     AAGVCLAAWWLRGLRYRSILSSLGIPAGAGFSVACIFVSQTANLIVPARLGDLVRIFI
                     LRHEYGSTASQGISSLVVERVFDILMVAVLGAVSLLFVLNVPDWFYTIIIVPIVGGIA
                     FFFFLVLAGKVSSENRIMRVVLTIVGQVREASLSLKALFFLSVSSIVIWLMDVLVCVF
                     VVLMFQEQVPLAVIVLGIVIGNLVKAVPLTPGGVGTYELALALTFTLAGVPAPDAAMI
                     AVIDHLIKNLITLGGGIVSIYFFGGWVLDSIRSAIQDRFGGMKSG"
     gene            complement(18681..19397)
                     /locus_tag="PK679_06815"
     CDS             complement(18681..19397)
                     /locus_tag="PK679_06815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HPC55702.1"
                     /translation="MPKDTVTVVIPVFNDRESLSVAIPRSLEAIAPVSPNFELIVAED
                     GSTDGSALVVRDWESRDNRVLLLHSDERLGRGRALARAFSVARGDIVCYYDVDLATDL
                     AHLSELVGAIREGYDIATGSRLLPGSRIDRSGSRELASRSYNFLVRTILGSRVYDHQC
                     GFKAFRKERLLSLLPEVRDTHWFWDTEVLVRAQRKGYSVRELPVRWREGRGTTVKRKD
                     VYQMGKAILRLWWQLHVEKG"
     gene            complement(19400..20626)
                     /locus_tag="PK679_06820"
     CDS             complement(19400..20626)
                     /locus_tag="PK679_06820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004079110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC55703.1"
                     /translation="MKICIVGGGLTGLCAALFLGKEHEVDLYEKRSHLGGCVSSYEIG
                     NTHIESFYHHCFAGDSNLFSLLDTLGIRDRLEWLRGSTGYYIDGRIYPLNTPREILSY
                     PYLSLPDKAKLALITLRSRRMDTASLDEITARDFIISELGERIYASFFEPLLASKFGD
                     FRDRVSAAWLVSRIAIRSNRGLSGERLGYLKGGFYTLINALSDHVGKDCVVRLGDAVS
                     RITRDTWGWRVNDQKYDVVISTIPPQALPAGTVTGIDPVPYQGAACMLLGIERDVAGG
                     IYWLNMKDPAPYGAVICHTNFVPRDRYGDHLVYLASYFHGDLPKKTDERMLSDFCQRF
                     GVTRDEVHWQRMAVDPWAGPLYTTGFAKKIVPYRAGGLYFAGMFSGPNYPERSMDGAI
                     AAGREVADLLRRDLAD"
     gene            20810..21988
                     /locus_tag="PK679_06825"
     CDS             20810..21988
                     /locus_tag="PK679_06825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tubulin/FtsZ family protein"
                     /protein_id="HPC55704.1"
                     /translation="MKMFFIGFGQAGGKIVDMFLEQDRKIGRNSFRGIAVNTARTDLM
                     GLKHIDMKDRILIGQTVVKGHGVGTDNAAGARITLDEIDSIVSGIDRRGTHDVDAFMI
                     VAGLGGGTGSGGTPVLARALKKIYREPVYVLGILPAPEEGRLYSYNAARSLTTLIKEA
                     DNTFIFDNSAWKNEGESIKSAFSRLNDEIVRRFGVLFRAGEVGSAGVGEMVVDSSEII
                     NTLRGGGITSVGYAITEVVTKKSKPSVSSLIGGIKGTLRKREATEEGLLGEDRTAKII
                     SLVRRAMLGRLTLPCDYSTAERALVLVAGPPDELDRKGIEKAKSWVEENIAGVEVRGG
                     DYPVNSSYVAAVVVLATIANAPRIRELMDIARTTKEDVAKSQERKPITLDEEIEPLFE
                     "
     gene            21993..23126
                     /locus_tag="PK679_06830"
     CDS             21993..23126
                     /locus_tag="PK679_06830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55705.1"
                     /translation="MRNVCTCVVVLFLCLLVQGIAAISVGNIAITPSGSLISGQTQVR
                     STFIIEFPASGGKTFDDTNSLQLSSEMDNPTWTYSLVLDEVENPSKTEVGQNVNINGW
                     LLSYPAKRELSMKVTMEGTAPVVDGTSEKIVIAVRELDSKGKAIASSEVIKKALVINP
                     SQVKESIQQAREKLASLRSEIDAAMIPGLDLSAVEAKYNEANTAIQNADSTSDYSRAQ
                     SYLNTAISAISDAQTLLSEFTIQKTLNDADAKIGEVSSLITDFRVNKSMGSDPRLTPI
                     LLAHDNAAGLVSEARDALSAKNYDQARTKATDAAAKADEALAEAYTLKQQVESNPLSG
                     AASMAAGILVGGMVIIVAVVVIAIVAIVGYLLFRRRRKWDELG"
     gene            complement(23418..25055)
                     /locus_tag="PK679_06835"
     CDS             complement(23418..25055)
                     /locus_tag="PK679_06835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03663 family protein"
                     /protein_id="HPC55706.1"
                     /translation="MVFIIALLLRLLFLDFKLLHHDEAIHAWFSYELLTKGTYIYDPM
                     YHGPFLYYITAGMFFLLGQSDAVARILPALFGAAIVPLVYAIYRLGYLDTRQALVAAL
                     FIAISPDLVYFSRFLRHDTFQLFFSVLLLVALLAYLERGKIGYAVLAGLAAGGGMCLK
                     EDMPLFLVVVIVFGIYLLWRRDVAFPRTWIRDGVLAILVSISVMALFYSSFGVHPEIL
                     ETGVIKAYTHWAAMHGQCRICGPWFFYIVLFLLYEVPIFILALFGMVQFADRHNPFPG
                     LVARVQNRIHDWKVHRLRNEVPDEVVHDQLTGPNVEETNGSYKDLFKQNKNRVPGFHS
                     KRELFFLFCITWFVASVAAYAYIGEKVPWLIIHQLLPAILVSMYLMSEKKVVFALAGC
                     AFLILMTFHVSFSPGNINEPIVQVQNSEDLRIVMKLIDASDSVVIASENYWPLPWYYR
                     GDGWNKMHFYGKIVDEATIFSVDPDMVITHDQASYPALPGYDKKTYKLCYWFSIYDNE
                     NRIFEYYVKRDGKIGSINIDVFTKPGLYAKADLSPPV"
     gene            complement(25128..>25372)
                     /gene="rpsJ"
                     /locus_tag="PK679_06840"
     CDS             complement(25128..>25372)
                     /gene="rpsJ"
                     /locus_tag="PK679_06840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HPC55707.1"
                     /translation="IREIAERTGVNLAGPIPLPTKRLVIPIRKSPDGEGTATWDRWQM
                     RVHKRLIDIDADERALRQLMRTQVPKDIGIEIVLES"
BASE COUNT         5952 a         6787 c         7168 g         5465 t
ORIGIN      
        1 tgcgccccct tcgcgtgtat tccctgtccc aggcatggcg gaagcggttt tccataatat
       61 ccctcattcc tgctgcgaag gcgaggtgaa ccgtctggag aatgaccaaa aatattgggg
      121 actaataatc atataaaagg gctggaacag atgaaagaca agggggagga aggatcaatt
      181 cctgccggga atcgattaga ggagaccgaa tgatttcagc gtcacttccg ggttgactgc
      241 accgcagtga tagaccactc cctcggagat ctcattgatt acgacttctg caggagaaaa
      301 cagcgacgta tcaatcttgt agaagtcgta ccccgcttcc ttgaagatat cattgaatgg
      361 tttaccgtaa ccctttgact tgttactcgg tattttctca aggtaatccc gaatctcggg
      421 tgctttcatt gtcagcataa tccggccgtg atagatggtt gcatcgtttg tgacacccat
      481 tgccattttt ggaccacgaa ccgggggtac cggggcagtc ccgatggcag cggtaatctt
      541 ccgggtatca aaatggagtt cgttcagttt gtatacagct gtctcgacac accgcccgga
      601 aacctggatt gagcccacga ttgatgatgt gggggcgacc actgcacaga cgtttgccac
      661 gtccacgtga cagtcctctg cgatcttttc catgacctga gcattgggga ggtggtcact
      721 ctcgagggcg ataaccgcag aatcgaagtc atcctcgtac tcgatgacct cataagtatg
      781 ctttggcttg agtgacaatg cccttgcggg cccgctgccc atcgcaaagt agttgttatg
      841 cttgatggtc caccctgcct tctgcgaacc gaggcaggca atggatggaa agtcggtgaa
      901 aacatcgatg aacgggagag ggtagtcctt tatggatgcc atccggaaat tgacctctcc
      961 cagacccccc atgcagatct ccgtgaaagc acgacctgct gcatacccgc cgcgtgtact
     1021 tacaccacaa tcgataatcc gggccccgtt atcgagttca tggtacgtgg cattgaattc
     1081 ttcagcatat tccgccagat tctcaaatat ttcaagggca agttcattga cactgagcac
     1141 gtggagtacc ccctttacca tagaacatac tccgataaga gataagagtt atcaaattat
     1201 tgttttataa aaagggttca ggagatatac tcgcagattt tgacagggtt gtagcggaga
     1261 gtaatcatcc ttgtacggcc tttaccgtcg cggtattcga ggtttaagag gcgcatagca
     1321 tcgagttttc tgataatttc gtagaaccgt gtatagccaa gctccgtctc ctgcctgacc
     1381 acctggtaca cgtcccccgc gttcatctct ccaccctttt ctgcgtggcg tgcaatgatc
     1441 ccaaggacag tcctttcttc cggcttgaga cttttgacgg atgatgcgag gtgaaggtac
     1501 cgggaaactt tgtaagctcc acagatatct tcccgctcta tcttccggct ggctctcttt
     1561 tcagcattca gccccgcgcg cttgagcagg tcaataccga cacgaagatc cccgctcttc
     1621 tgggtctgct ccaccacgag ttcaaacaac tcgggggaaa ggcagcccat gtacaggccc
     1681 tgctggacgc gttcgccaat gattgttcgc acttcctcgt acgtataggg agggaagtag
     1741 atctccgttg gccggaaaac tgaagatacc cgggcatcaa ggacacgcga gaggtcaaca
     1801 tccatgtcgc tgatgatgac gattacaccg atccgcgtac ctggatacgc ctcgtgggag
     1861 cggagaagga tatagaggac cctgttgagt tcattctcgt agaggaggta attcgcatcg
     1921 tcaagtgcca cgaggagaac ctgctcctcc ttctggagaa tccttgcaat cgcatcaaat
     1981 acctgcttga aggacgttcc tgaagagggg gggaggtgtc ccgagagttt ccggtaaatc
     2041 tgtgaaaaaa ctgcaaactt ggtattatca atctggcagt tgacgtggat ggggaccagc
     2101 ttctttgtag tatcttcgat ttctccgaaa agcttcctga tactcgttgt ttttccggtc
     2161 ccgggaagtc ccctgcagac cgtgttgagt ggtcgcccgc ccttcatccc cggtttaatc
     2221 tggaacgcga gttctctcat ctgggtctcg cggaagttga actgctcggg cacgtaatcg
     2281 atttcaaaga cttccgggtc ccgaaagagg gtctcatccc acatgaggat gtctttgttt
     2341 atcccgctca ttggcctgtc acagctcccc agggcttcgt ttccgggtaa tctacacgtt
     2401 tttgaggcat ttcctgcaca gcgtcctgct tgcaaagagc atgctcatct tctgttcagc
     2461 cggtttgacg ggaacaccgc actcctcgca cgttgggacc ccctctgcat ctcctgcatc
     2521 tgccggagat ggttttgcag cattgacctg ctgtgcggga acctgctgcg cgacggctgg
     2581 agggggttct gccggccccc cggctacctg tgtttgtgcc acaacggtct cgtttttgct
     2641 cctctccggt cccgggggga ggatgcgtcg acggaatgcc tccaccctct ctttcgaggc
     2701 agggtctccc tgcccgaact tctgcaggac ggaatcaagg aagctgatga gttcatctgc
     2761 atctccctcg ttcttgacgg ggccgttcac ttccaggcgg aggttctcat aattttcaag
     2821 gttcacagtg atcccgatag caagtgtcct ctgcccttcc attgtatcat attcagcatg
     2881 tatttctaat gaaagtgccc ctgacagatc cccccggggg aggcatgcac caatcctttt
     2941 ttccttgcct caaggcatcc gggcagacca ggcggattca ttcatcaggt cacggtgacc
     3001 tgtgcacccg cgttgcagcc ggttgtgcgt attatgtcac ctcccccggc ccgatccagg
     3061 gtcttcctgc aggccctttc gatagccccc gtatcaccct cggtgaaagc aaaaacgacc
     3121 gggccaaagg agctcaggcc tgcacctgct gcaccttcgt cccgcatggt ctccatcaga
     3181 tcctgggtga tgggaggtgc aagcatgttc tcgattttct tgaacccgag tccctgcatc
     3241 ttgttcacgg cacgtccgaa gaggtcaaga tcttcctcca cgagagcagg gaggagggag
     3301 acgaggacga ggtggcagag ttcccggacc tcgtcaaggg ggacaggaca atggcttgaa
     3361 aagaggtcct tttcacctgt gccactcgct ccgatgcagg atttcggcat ggcaaggaga
     3421 attttccacc caacagggaa cggatggcgc aggataactt cgggcgggcg gacaccacgg
     3481 gaggccgacg aggggagaaa cccggtttta tctttcgaat cgccgaggga gtggcctgca
     3541 tcacagatga accctccggt cgcaaaggtt gctgtaccta tccccgatgt gccgccacga
     3601 ccagttatcc gggcaagatc acggggactc tggacctgcc cgtagaggtg gcagagtgct
     3661 gttgctgtcg agagggcaag ctgggttcct cgcccgagac caacgtgacc cgggtaaaca
     3721 gaccggatag tgaactcggc cccgccgggc aggcatagtg ccccggcaac agactttgct
     3781 gctgcaagaa cacgctcccg ggcatctgcg tcacctccat aaactgtgaa cccctcactc
     3841 ctgcgggcag agaggacaac ttcaggcttc ccgagtgcga gtccaatccc cccgtccacg
     3901 cgaccgaggc tcccgttcat gtcgatgagc ccgaggtgga tgcgggacgg tgcccggaca
     3961 agtacccgcc gctcacctgt aaaggatgct gcagggaaca cctcttcgat gtgcatgagg
     4021 gggaaatcgc catggataat ccggtaccgt cgcgaaagga agagagggtt tccggagagc
     4081 ccaaaagcac gggcaatatc gggtccgcgg gtcccggcag acattccgag tatctcccgc
     4141 ctggtttcca gcctgtggtg ttcgagtatc tttccaatgg gaacatcggc tcgcatgagg
     4201 tcatcacgga aagaagaaga aagccttgag aggggggtat acgactcggc ataaatgagg
     4261 gtctctccgg tacgcgtatt cttcagctcg acaatccggt ggttgacttc gtcaccgggc
     4321 tgcacctgga gattctctgc taccgagggg tcagcttttt caactttctg cacccgcgtg
     4381 gtgacagcga ccggagcgcc gcatgcaagt tccaggatgc gcgttacgga accgtcggtc
     4441 ccgagaagga cacgctggag gggagagagg gggcctgccg tccgttcgag atcatcgcac
     4501 gggaagaatt ctttcatgtt cccaggtgga gatagtgctc tcttccatac aatccttccc
     4561 cagtggtgtc agccaggtgt accagtgaga aacaggggca tgaattgtgt tccctcgagg
     4621 acaccggatg acccgtctgc cgcttcacgc tcgcaaaagg atttgcaccc gtctttcctg
     4681 cctccgagga tggcgaacgg aacggggtca ggcgagtgtg tacgaatgcg aaggggcgtt
     4741 gggtggtcgg gaaggactgc gatacaggcg ctgcatccat cgaggatggt cccgatcatg
     4801 gcatccacgc gctcgatggc cctgaccttc tcgacaagac tgccaaggtg gccagcctcg
     4861 tccggcgcct ccacgtgaac atagacgaaa tcgaggtacc ggagtgcgtc gagggcataa
     4921 cgggccttgg cctggtaatc ggtatcgagg taacccgtgg caccagggac gttgatcacc
     4981 tccatccgtg cgcaccggcc aatgccgcgg aggagatcga cagcagatat catacctccc
     5041 gatattccat atttctcggc aaatggcgtg agtgcaggag ttttcccccc gctccagggc
     5101 cagatatggg ttgcgggggc aagaccgcgg gaaatcctgg cggaattgac gggatggtgg
     5161 tcaaaaaccc gtcctgacgc ctcgatgcag gaacggagga cctttgcgtc cttcccgtcc
     5221 gggaggtacc tgtcgatctc ctgtcccacg atatcgtggg gaggaacagt ttttgcaccc
     5281 ttggcatccg ggagaacgag gacgttcctg tagcttacac cgggaaagat tcggaccggg
     5341 gagataacct tctggaggtc ggataagagc gctgcccctt ccgcactcgt aatgtgccct
     5401 gcggagaagt cagtcatggt cccgtccctg atggtcacca ggttgcagcg gtacgccatc
     5461 tccgtttctg caaggtcaat tcccatgctt gccgcctcga gcggtcccct gccggtgtaa
     5521 tatttccgcg gatcataccc gaggatcgag aggtttgcga tatcggagcc tgcctcacac
     5581 cccggaggga tggtgcggag gaggccgcaa cacccctcgc gtgcaatgcg gtccatgttc
     5641 ggggtttgtg catactcgag gggtgtttga cccccgagtt catcgagggg ttcatctgcc
     5701 atcccgtctc ccaggatcag gacaaacttt ctttctttca tgctcctcca aacagtttca
     5761 tcaggcccag caggggcagt gtggtgataa gtgcagccac gaatgctccg cctgcgatcg
     5821 ccaggaacgc ctcccggaac cgtatccgga atacaaatgc cgcggcgcac ccgctccatg
     5881 tccctgttac agggatgggc attgccacga agaggaagag cgcaggtgca ccgtatcgcc
     5941 gtatctgctc ttcatgtcgc cctgtcctct caaagagcca ggagaaaaac cggtccatgg
     6001 tttgtgaacg gacccggagc caccctgaaa cgggatcgag aaggaggagg agcgggataa
     6061 ccgggagaag gttcccgata attccaagtc caaaagccgt caatggcgga aatccgtaaa
     6121 gaatcgccgc gggaatggca taacgcgcct cgaagaacgg gagtgccccg aggatgacaa
     6181 cagtaagggc agccggaatg tccattgcct actccagcat cgctgcaatc gccatcctga
     6241 cgctctccct cgacccaagg gggggtttcc acccaagcga cttcagtttc tgaaccgaga
     6301 gctgcatcct cgggacatcg ccgatccacc cgcgttctcc gccggtaaag atgtactcta
     6361 cgccggacag gcccatctcc tccacaacga ggtctgcgat ggatcggaca tcaatccagt
     6421 cctctgaccc gatattgaac gtgttcaccc tgccagatgc atggtctgca gcatagagca
     6481 tggcgtccac gcatgcactg acctccaggt atgacttgga ctggcgcccg tcgccgagga
     6541 tctcgagccg gtgcggattg ccggagagct tccgtatgaa gtcccagata acgccatggt
     6601 tactcctctt tcctatgata tttgcaaacc ggaatatcca ggctttcatc ccgaaactat
     6661 gacagtatgc agatatgaga gcctcgcagg agagcttggt ggcgccatag acagagacgg
     6721 gttcgagggg tgaatagtcc tctggcgtgg gaatgacctt tgcatcaccg tatacggtcg
     6781 aggtcgacgt gaagacgatc tccgggactc ctgccgccct catcgcctcc aggacacgcc
     6841 aggttgcaag gatgttctgc cggacctggg actcgggggt gagggctccc tgcctgacgt
     6901 cgggatcggc tgcaaggtgc catacccttc ctgctccgga gaggaagtcc tgccagccgt
     6961 cttcaaggag gtcggccttc ctgaacagga tcctgtcccg ggacaggtgg gcggaaaggt
     7021 tctgttccga accgctccgc agggaatcta tgacacggac cgcctcccct cgtgccacga
     7081 gcgcgtccac gaggtgcgaa ccgataaacc ctgcacctcc cgtcactacg caggccatca
     7141 taccctaata tatgtgcctt tcatgtatag gaatagtgtt atgtttatcg ggatcgacca
     7201 cgggacttca gcgatgcggt tctcgggtgg gccgggccac aggtttaaaa tgaggaggga
     7261 agatgccgtc agtttcgaga tggaagatct cgaagagatc tgcccccttg atgaaatcga
     7321 gggtatcgct ctctcctact cgatggggga caatttctcg gcaatcacac ccgtacgcaa
     7381 actctcaaac aggggactcg tcagcaggga aggtgccggc aagcacatag gaggaggaac
     7441 gagggtcttt gaccgggtag cagagagttc gataccagct gtcgctgtcc ccggcctcca
     7501 ccggggttca cccacggatc cccgcttccg cgtttactca caccaggcga gtcccgaaaa
     7561 ggttggcatt gcgctgaggg tgacacagga tctcgggcgg gacgttgtga tttctgatat
     7621 cagttcgaac accgttaccc tgattgtgaa ggacggaagg cttgcaggcg cccttgatgc
     7681 ctgcatcttt gcccccggaa cagaacatgg tgcccttgat gtggatgcca tacggaagat
     7741 cgatcgcggg gagatttcgg caaaccaggc attcatgtca gcaggtgtaa accatactct
     7801 tcccccggag gagaggttgc ctgcactggg gctttttgct gccatggaat gtgctgcgct
     7861 ccttgttctt gcaccacatg cccgcgtggc cctgtccggc agcatggcgg cagctgtggc
     7921 ggagactgtc cagtccctgc tggggaggga gataacagtt tatgacgagt ggtgcgctgc
     7981 agacgggctc tccctcattg cccgggaggt tttctcaagg ggtgccggta caattctcgg
     8041 tctttcggtg aacaggtgaa ggttcgtatc gcaccatttt attatgatta ataatgtaaa
     8101 attataccgt gatttccttg cgtgagctgc gcattcatgg tcgaggcggg cagggttctg
     8161 tcactgccgc agaattgatc gccgtggcag cctttgcggg gggtgtgtac tcccaggctt
     8221 tcccggcgtt cggtgtggag agaaggggtg cacccgtcca ggcatttgtc aggtttgatg
     8281 acaggaagat ccggttgaga agccaggtgt acgagcctga ctacatcatt gtccaggaca
     8341 gcacgctcat cagtgatgtc aacgtcttcc atggtgtcaa accgggaggg gtcgtcatcg
     8401 tgaacacgga aaaaccactg gcggcacagg tccctcccgg agtcaaggtc attacactgg
     8461 atgcgaccag tatcgcattg aagcaccttg gggtccccat caccaatacc acccttatgg
     8521 gggcttttgc cgctgcgagc ggcgagatcg atttcgcggc cctcgaagag gcaatccgag
     8581 gaaggttcac gggagaaatg gcagaaaaga acgtggcagc agcacgcgag gcatatgcca
     8641 ttgtgaaggg ggtgtcatga ccatgacgct tggtcttggc tgttcatccc gccccgggac
     8701 atcccgtgtg aacaggacgg ggagctggcg gacttttcgc cctgtctttc tgcgggacaa
     8761 gtgtacgaaa tgcagattgt gtatccagct gtgccctgag gggtgtatca tggaggaaag
     8821 cgaaggtttt cctgtgcctg actatgatta ttgcaaggga tgcgggctct gcgccgagga
     8881 atgccctgcg gaggccatag agatgcagaa ggaggagaaa taggatgatg gagatcatgg
     8941 aagggtctca tgcagtggcc cacgcagtgc ggatgtgcag gcccgaggtc attgcagcct
     9001 atccgataac cccgcaaaca catatcgtgg aggcccttgc cgagatggtt gccaactgca
     9061 gcctggatgc agaatacatc acggtcgaga gcgaattttc cgcactttct gcatgccttg
     9121 gggcgtctgc ggcaggatca cgcgtctatt cggcaacaac atcgcagggt ctcgccctga
     9181 tgtttgaggt gtgtttcaac actgcaggat tgcgcctccc ggttgtcatg tccatcgtca
     9241 acagggcact gggtgctccg ctctccatct ggaacgacca gcaggattct atctccctgc
     9301 gtgattccgg atggctccag ttctatgccg aggataacca ggaggcaacc gacctccact
     9361 acattgctta ccgggtcgca gaggacaaga gcgtcctgct cccggcattc gtctgccttg
     9421 acggtttcat cctctcccat acctatgaac ctgtggaaat gctcacccag gaacaggtcg
     9481 acagctacct gcccccgtac agtcctgtcc agcgactcga cagtaagaat cccatctcga
     9541 tcggcctttt tacatcacct gattactaca tggagttccg gtacgaaatg gaccgtgcaa
     9601 tgaaggcttc ttcgcaggtg atcagggaag cagggcgccg gttcggggag atgtttggaa
     9661 gggattactc gaacctcgtg gaggagtacc gcttggacga tgctgagtgt gcgatcgttg
     9721 ccatgggatc catctgcggg acggtaaagg acgccatcga cgagatgagg ggggacgggc
     9781 agaaggtcgg gctccttcgg atacggacat tccgcccgtt ccccggagag gaaatgaaaa
     9841 aagccctctc gggggtctcg agcgttgccg tccttgacaa gaatatctct cttggtgcaa
     9901 aaggtgcagt ggcgctcgag gtcagggatg ccctctacgg gagcgggatc ccgatcctcg
     9961 actatatcat cgcgctggga ggaagagatg tggcaaagaa ggacatcaaa tcagtcgtaa
    10021 agatggcaat ggccgggaag ggagacctgt tctacggcct gcgcggggag gtgctcggat
    10081 gaagggtgag cagtgttcac tcttcgatcc cgggcaccgg gcatgcggtg gctgcgcggc
    10141 ggcacttgct gcacgggctg ttctcgatgc cgccggaccg gacacgataa tcgtctctgc
    10201 tacggggtgc atggaggtct tttcgactcc ttatccggag actgcatgga aagtcccctg
    10261 gatacactcg cttttcgaga ataactcggc ggttgcatcc gggatcactg ccgcgctcaa
    10321 aaagcaggga cggaaagaaa aggtaatagc gctgggcgga gacggggcca ctttcgacat
    10381 cggcatgctc tgcctctccg gggcattcga gcgtggccac gatttcgtgt atatctgcta
    10441 cgacaacgag gcctacatga atacaggtat ccagcgctcc ggagcaaccc cgtatgatgc
    10501 aagtacgacg acgagcccgg cgggaaaatg ttccacaggg aaccgacggc ccaagaagga
    10561 tctcccggca atccttgcag cccatggggc accctatgtt gccactgcaa cggttgctta
    10621 ccttccggac ctgaaaaaaa aggtcaaaaa ggccctcgac acggagggac catgctatgt
    10681 gcaggtacat gcgccctgtt gcacgggctg gggttttgag ggtgaaaaga cgctcgcgat
    10741 cgcacggctt gcagtggaga ccggtctctt cgtcagcttc gagatggaga acggggtggt
    10801 gacccgggtc aagaaagttg tcagaaaacc tgtcgaggaa tacctgaaag aacaacgccg
    10861 tttccgccac ttattccgcc cgaagaggaa cgatgcagag attgcaaaaa tccaggccat
    10921 agcggatggg aacgcacaaa aattcgggat tgatattaat ctgaagaaat gaactccctt
    10981 tttgaaaaaa gtaccttttt tattccagtg tgaatctact ttaatccgtg agaaacgatg
    11041 caacctgcgg cccccgggtc cttttcatgg atgatgacga gggcatacgt gatgttgtca
    11101 gggtgttctt gtccggtctc ggataccgtg ttgaggtcgt tgcagacggc ggaagcgtga
    11161 tagaatcgta caggaaagcg atcgaggagg gtgatccctt ccgggttgtc atccttgacc
    11221 ttacggttag tgcgggtaaa ggaggtatcg agacactccg ggagttgaaa tccatcgatc
    11281 ccgaagtaaa ggccgtcatt accacgggtt ttacagatga ccctgttttt tccggattcg
    11341 gcgcgcaggg ttttgttgca gcaataccaa aaccgttcca cgtcaggcaa ctggatgaga
    11401 ccctccgtgg aatcctctcg tgagacgcat cacggggaaa tatggtcctt ccgccaggta
    11461 aggaggaacg ggacgagcat cacgattgca atgacgaccc agatatttgc aaagaggtac
    11521 aggagatcct cgcgtccctt ttcgtagaac ctgatctccg cgatacgtgt tgtattccac
    11581 gatatctccg ttaatccttc cgggaggtct gtgactgttg ctccgctgct caccatgccg
    11641 agcgcggggt tccggacatc aaaaccggcg ggaagaacga tggtcacacg gcggggtcgg
    11701 tcatagatcg caatgaaatg gttgtcgcgt acgggtccct ggaaggtgag cgtatagttc
    11761 ccttttggaa aaagaattgt attctcccct ctccaggaaa acgtgcaggg ggaacagttc
    11821 cctgtaagcg ctacatccac cactttcacg ggaacccgct ccccgaggat acccgcctca
    11881 aaaaactcat atcctgtagc atcagcgaga tcgagggatg cggaataggc agttccgttc
    11941 gggaggatat ggtagtcggc cctgctcgcg gcacagggca ggatcacgag cagaactgca
    12001 atgcagagag taacgaggga agatccgcgt cgatctccag aggtgctttg cattgtcgta
    12061 tcaccgtctc cgggtccttg aggaggtgcc cggtcaccac gcatacgata gtctcatccc
    12121 tgtcgataac accggtctcg atgagctttt tcactcctgc gaccgaggcg gccgatgcgg
    12181 gttccacgcc gataccctct ttttgagcaa ggtcgcgctg catcgcgagt atctcgtcgt
    12241 cggttacggc ttcggcacag ccgccggtct tcctgattgc agcaagcgcc ttctcagcat
    12301 tgacgggtgc cccgatacgg attgctgtcg caaccgtctc gggctgtggt tcaggttcaa
    12361 cttcggcgag tccctgttgg attgcccgga cgaccggtgc cgaacccgcc gcctggatcc
    12421 cggtcatcat gggcattccg ttgagaagtc caagatctgc aagttccacg aaccccttgt
    12481 aaaccgcaga tatgttcccg gcattcccga cggggagcac catgcgatcc ggcgatctcc
    12541 caagctgatc aagtacctca aacccgatag tcttctgtcc ctcgagccgg aaggggttta
    12601 cggaattgag gaggtagagc ccgtgggaga ggcacagctc gtggaccagc tcgagtgccc
    12661 ggtcgaagtt tcccctgatg gaaagcacac gcgcaccgtg catcagtgcc tgggcgactt
    12721 tgccgagggc taccttacca gcaggcagga ggacaacggc agggattcct gcccttgccg
    12781 cgtatgctgc gaggctcgca gaggtgttcc ccgtgctggc acaggcaacg gatgtctttt
    12841 tgagctggag cgccatgctc acgccaactg tcattcctct gtccttgaaa gaacccgtcg
    12901 ggttcatgcc ctcgtgcttt gcatacaggt tcgggacacc tatttcttcc ccgatacggg
    12961 taagatggta aagcggggtt ccaccttcct gcagggtgac gggagggatc gagacgggaa
    13021 ggagctcgcg gtatcgccag acggaaagcg gtctcctctc ccatacctcc ctctcgatca
    13081 tgatggaatc gagatcgtac tcgactgcga gcaggtgacc gcagaccgtg cagttgtaga
    13141 tgatctcgtc gggggaatat ccctttccac acccgacgca cacgagacgg tacatgtaca
    13201 gtggtaatca ctctccgagg gtaaatagga ggtggccggc cgggggaaaa gagggacccc
    13261 tctttttaat tcccgcgtcg ggagggttca cgggcgcgtt ttgtccgact ggatgatatc
    13321 cggatggcgg tctttcttga ccgggaacgc attgcggact ctctcgacaa actccctgct
    13381 catttcacag gaatagaccc cttcgcctgc cccggctata aaaagcgggg cgccggttgg
    13441 atccgcaacc atcgttccgc cgttgtaggt gtcgacaggg gttacccctg ttgtattgat
    13501 accggcaacg taaacctggt attcaaccgc acgggccctg atgaagagtt cccagtgaga
    13561 gaggcgggac gccggccagg cagccgggac gagaacggcg tccacgccgg catcggcata
    13621 cagggcaaag atggatgcaa accggagatc gtagcagatg gcaataccca gcgtcatccc
    13681 ggcgagagtg aatggtgcaa tggcgttacc cctctgatac acgcgatcct cgccagcggg
    13741 agaaaaaagg tggcacttcg aatactcggc gagtatttta ccctgcggcg atatagcgat
    13801 acaggtgttt tccgggcgcg gaactgagta tttccgcagg gatccaagga ttgcaatgga
    13861 atactcttct gcgagggact ggagatgacc aacaagaggt ccatccagac cctggacatg
    13921 ccgcagcgag gaaggatccc agccggtagc gaactgttcg ggaaaacaga cgagatctcc
    13981 accatttcgg gatgcacggc caatgcagcg ttcggcacgg gcaagtgtag cctcggggtc
    14041 ttcccatgaa ctctctatct gtgcgcagca cagtatcata ccagttgaac taatgcatgg
    14101 aaacaccatg atgtttcctg atcaaccgga tggcggcctg tggcggaaaa acaccccgat
    14161 gcaggaaaaa aaggtcagaa ataaaggata aagagtactg aaatgaagaa aaaaggtttt
    14221 ttatgaatgc tattcgtaga gagagggttc atcagtccgc ttgtaggtga tgatctcatc
    14281 gggggagaag tggagcgata tctcgcgggc tgcactggca ggggaatctg aagcgtggat
    14341 aacgttcctc ccggtatcaa gcgccaggtc accacggatg gttcccggtt cggcttccgc
    14401 agggtttgtt gttccgatca tcttccggac cacgctgacc gcattcttcc cctcccagac
    14461 catcaggaaa cagggaccgc tttcaataaa gtgacgcagt gaaggaaaga acggcttctc
    14521 gaggtgttcc ctgtactgct ccaggaccct cttttccggt atcctctcaa aacgtgccgc
    14581 aacaagcttg agaccctttc tctcgaacct ctggataata ccaccgatca gtccccgggc
    14641 aaccccgtcg ggcttgacca tcacgaacgt gcgttccaac gatgctcact cctttcccgc
    14701 agccttccgc ccggcctgtg tccatgagac ccgccttggg gccctcccga gacggaagtt
    14761 attctggcac tttgtgctgc agaagtaaaa gacagacccg tccttgcgca cgaacatctt
    14821 accggtgccg ggttcgatag catccccgca gaaactgcag tttctctgtt cgaccatggt
    14881 tttattcacc gtctggagag ttttttagcc tcacgctcgg tctcgaggag catcaggaca
    14941 tcaccctccc ggatgggacc gaccgtgttc cgcgtgatga tgcgaccctt gttcggcccg
    15001 tcgaggatcc tgcacttcac ctgcatggcc tctccatgca tccctgtgga gccgatcacc
    15061 tcgattacct ctgcgggcgt tccttcatca gccattaccc catcacgctc tcagttcact
    15121 gacctgcttg acgatctcgt caaccagttc ctttgccttt cccggcttga caatcgctgc
    15181 agcagccgat cccacgtcaa gcccgctggc ggtcccgata tcgttctgct tgttgatgaa
    15241 aacgaatggt atctttttct cctcgcaaag cgggggaagg tgcatgacaa tctcttcggg
    15301 ttccacgtcg gccccgatga gaacgagtgc agcaatactg cgttcaattg cctttgttgc
    15361 ctcgttcgac cccttcttta tcttccccgt ctccctcgct atctccagag cctcaagtgc
    15421 tttgttctgg atctcttcag aaacctgaaa tttgacatac gactttgcca tgactcacct
    15481 cattcaggag ttgcgtagtt ctccctcatc actcatcagt cagtatcgac gatgtagcca
    15541 tatcaattcg acagatgcag gcataaaggt ttggaagagc ccagctccag aggggttttc
    15601 ccgataatgt cagccatcga gagcgtaaat caggacaccg ttttggttgt acacggtgac
    15661 aagaccggac tcttccacgc ggacgttata cctctccctt tccaagtccc cgacatagag
    15721 gtgggtcatg ttatagtgct tcatcagctc tctcgtcatt tcaggatcct cgtatattgt
    15781 cctcacatct gacagacgct ttccatacca cccgttggta tctgttcgcc acatgtactc
    15841 atggaaaggc caccctatga tcgttggaat cccggtgaag gatgataccc ttccgaagta
    15901 ggtataatcc ccgccctctg cctcgacaac acccttgacc cccgggagag accggaggaa
    15961 agcgatggca gaggcatcgc cggggtgcgc ggtctcgagg tatgccagcc cgtccagtgt
    16021 cccgcctgta tatggggggt cgagggggac agcgagcggt gtaacaatca gaatgactga
    16081 tacaaccgcc agtgccagcc tcccggacca tgcagggaag tatccggggg gcacacgtct
    16141 ggctgccatc gtggagacca tggaaaagga ggatgccccc atcagcagcc atgctggaat
    16201 gtagaactta aagacggtgt tcatccggta ataggtttca cccatgttgt ctttcaggta
    16261 gaaaaattcg cagacaatga caattgcaag gccgagcatg gcgagtatct ctgcaggagt
    16321 ttgcctcttt cctgccagca ggtaaacaag gggtacagtg gcaatggctg ctgcagggaa
    16381 tccagccagt gcaacgactg cgggagcgat gagaaaaagg ggccttttcc atatatcatg
    16441 ggccacgtag agtaccatca cgaggatgaa aaacccgtgg acgagcagga actcaacagg
    16501 tgcagtgggt gtatggacga ggcccactcc cagaatgccg ctcgtattca tctggaggta
    16561 aaaggggaga tagcagagca ccgcagtaac cggtacaagg aaaaagaaag acccgtgcgc
    16621 ctcaagaatt atcgcgggca ctctcccgat tccgcctaag cattgcgcac atcggagctg
    16681 aagtccagat tttgctgaat taacaagacg ccggacatac ccggtaagac ccctccaaaa
    16741 accggtgtat tgtggggatt tttttgcctg ccgccagatc atgaagccaa agatgagcgt
    16801 taccggggca tagacaataa tatcccatgt attgatgggc ggcatcgatc caagggataa
    16861 cccgcaaata aggatgagga gtgcacggcc ccacacatcc agatctttga accggaggag
    16921 ggagtagacg agcaggaaaa taaagaggac ctgattgaaa atcccgatga cgtggggatg
    16981 gacgtcaccc cacaggaatg aaaaaagggg gtattcattg attgtattgg taattgtccg
    17041 cgtactgtcc cagaggacag aacctgcggc tttcccctgg ataacctgga ggatgaagga
    17101 tgggttcacg atgacaagag tcgcggggac catccaggga aaacgggggg ctatcatcct
    17161 cccaagggca tagagcaaca cggcagagaa tccaaacacc gtcgggagga caaggttgaa
    17221 tgagatctgt gacggtactc cactcgtgat gccgagcgct ccgaacatcc agtatccaag
    17281 atagtaatag acgttgagat aaccggaaga aaaccagggg tccaggggcg gcacaaccgg
    17341 gacccgcatg acggatgcaa gaaatgcatg atccatgaac ttttccgcat atgaaatact
    17401 tggattcgtg aaacggacgc tcaccatcga gaagaagaag agaaggaaag tagcgacata
    17461 aatccactgt gccgaccaga acctccctga atacccgttc ctggaagctg caaggagaaa
    17521 cagggccgcg aaaggcacaa gtgcaaggaa gacggggagc cggaagagac cgcagtacca
    17581 actgatgagg gaaaaaagga ggaaggatac gggaaacgaa acagggtagg catacccggc
    17641 aaaggcgcgc ctcagatagg gccagaccga gacctgaagg aagaaaagga ggaggagcca
    17701 ggaaagaacc gacaggatct gaaatgtata atcaaccaga cttcattccc ccgaacctgt
    17761 cctggattgc actcctgatg ctgtcaagga cccatcctcc aaagaaatag atggacacga
    17821 tcccacctcc aagcgtgatg agatttttga tgaggtggtc aataaccgcg atcatggctg
    17881 catccggtgc cggaacaccc gcgagggtga aggtgagtgc cagtgcgagt tcgtatgtac
    17941 caacaccacc aggggtcagg ggaactgcct tgacgagatt tccgatcacg ataccaagga
    18001 cgatcaccgc caggggcacc tgttcctgga acatcaatac cacaaagacg cagactagaa
    18061 catccatgag ccatatcacg atcgaactca ccgataggaa aaaaagagcc ttaagggaga
    18121 gggacgcctc tcttacctgc ccgacgatgg tgagaacaac cctcattatg cggttctctg
    18181 aggaaacctt tccggccagg acaaggaaga aaaagaaggc gattccacca acaatgggga
    18241 cgatgataat cgtgtagaac cagtcaggaa cgttgagcac gaacaggagc gaaacagccc
    18301 cgaggactgc caccatcagg atgtcaaaga cacgttcaac gacaagcgat gaaatcccct
    18361 gagaggcagt tgacccatac tcgtggcgaa ggataaatat ccgtacgagg tctcccagcc
    18421 gcgcaggcac gatcaggttt gctgtctggc tcacaaaaat gcaggcaacg gaaaaaccgg
    18481 ctcctgcagg gattcccagt gaggagagga tactcctgta acggaggccc ctcaaccacc
    18541 aggcagcaag gcagacacct gcggctagaa cgaggaaata ccacacagca tgctctgcgg
    18601 caacgaggag gtcatcccat attgtgtaga gcatgaagac cacgatcccc acagcgagca
    18661 gggtcgagat cacgatagtg ctagcctttt tccacatgca actgccacca cagccggagg
    18721 atagcctttc ccatctggta tacgtccttc cgtttcactg tcgtgcccct gccttccctc
    18781 cacctgacgg gtaactccct gaccgagtaa cccttcctct gtgctctgac aagaacctcg
    18841 gtatcccaga accagtgggt atccctcacc tcggggagaa gggagagcaa tctctctttc
    18901 cggaacgcct tgaacccgca ctggtgatca tacacccgtg aaccaagtat ggtccggacg
    18961 agaaaattat aggacctgct ggccagttcc cggctcccgc tcctgtcaat ccggctcccg
    19021 gggaggagtc gtgagccggt tgcgatgtca tagccctctc tgatagctcc aaccagctcg
    19081 gaaaggtggg cgaggtctgt ggcgaggtcg acatcgtagt agcagacaat gtctcccctt
    19141 gcgactgaga atgcccgggc aagtgctctt ccgcggccca ggcgctcgtc gctgtggagg
    19201 aggaggacgc ggttgtcccg gctctcccag tcccttacga caagggcact cccgtccgtg
    19261 ctcccgtcct ctgcaacaat gagctcgaag ttgggggaga caggtgcaat tgcttcaaga
    19321 gatcggggaa tagccacact caggctctcc ctgtcgttga aaacggggat gaccacggtc
    19381 acagtgtctt ttggcatagt caatcggcca aatccctcct gaggagatca gcgacttccc
    19441 gcccggctgc aatggccccg tccatgctcc tttcgggata gttcggtcct gagaacattc
    19501 ctgcaaagta caggccccct gccctgtaag gcacgatttt tttggcaaaa cccgtggtat
    19561 agagcggccc ggcccaggga tcgactgcca tcctctgcca gtgcacctcg tcccgtgtca
    19621 caccaaatct ctggcaaaaa tctgacagca tcctctcgtc tgtctttttg gggaggtcac
    19681 cgtgaaagta tgatgccagg tatacgaggt gatcgccgta acggtcccgc ggaacaaaat
    19741 ttgtatggca tataaccgca ccatagggtg caggatcctt catgttcagc cagtagatac
    19801 ccccggccac gtctctttcg attccaagga gcatgcaggc ggctccctgg taaggtacgg
    19861 gatcgattcc ggttaccgtt cctgcgggaa gggcctgggg agggatggtc gaaatgacaa
    19921 catcgtactt ctggtcgttt accctccagc cccaggtatc acgtgtgatc ctcgagacag
    19981 cgtctccgag acggacgaca caatcctttc cgacatggtc agatagggca ttgataaggg
    20041 tgtaaaaacc tcctttcagg tatccaagac gctcacccga taggccccgg ttggaccgga
    20101 tggcaattct gctgacaagc caggccgcag agaccctgtc gcggaagtcc ccgaacttgc
    20161 tcgcgaggag tggttcgaag aaggaagcat atatgcgttc acccagttcg ctgatgatga
    20221 aatcacgggc agtaatctca tcgagggatg cggtatccat tcttctggac cgcagggtga
    20281 tgagtgcaag ttttgccttg tccggaagcg acaggtaggg gtaggacagg atttcacgcg
    20341 gtgtgttgag gggataaatg cggccatcga tgtaataccc ggtcgatccc ctgagccatt
    20401 ccagcctgtc ccgtattccg agcgtgtcca gaagggagaa gagattgctg tcacctgcaa
    20461 aacagtgatg gtagaacgat tcgatgtgcg tgttcccgat ctcgtaggag gagacgcacc
    20521 cgccgaggtg actgcgtttc tcgtaaaggt caacctcatg ctccttcccg aggaaaaggg
    20581 cagcacagag cccggtcagc ccgcccccga cgatgcatat tttcatgtcc ggttcctggt
    20641 actgtttgga aaagggggat gaaaaaggct ccgcattgaa aataatctcc tttaattcgt
    20701 tttgcggtaa gtctggaata aggaaagtat ttgaacttcc gagagaaaat cataataatc
    20761 ggagaaaata aaggtccctt cgtaataacc gggctggtgt ttcagttcca tgaaaatgtt
    20821 tttcatcggg tttggtcagg caggcggcaa gatcgtggat atgttccttg aacaggacag
    20881 gaagataggg aggaacagtt tcaggggtat tgcagtcaat actgcccgga ctgatctcat
    20941 ggggttaaaa cacattgata tgaaagaccg catcctcatc ggtcagactg tggtgaaggg
    21001 ccatggggtc ggcaccgaca atgccgccgg ggcacggatt acactggatg agatcgacag
    21061 catcgtgagc ggcatcgaca ggagggggac ccatgatgtg gatgccttca tgattgttgc
    21121 aggtctcggc ggaggtaccg gttcgggagg aacaccggtt cttgcccggg cattaaaaaa
    21181 gatttaccgg gaacctgtct atgttcttgg tatccttcct gccccggagg aagggaggct
    21241 ctattcctat aatgccgcca ggagtctcac gaccctgatc aaggaagcgg ataacacgtt
    21301 catctttgac aacagcgcat ggaagaacga gggggagagt ataaaatcag cattctcccg
    21361 tcttaacgat gaaattgtcc gccgtttcgg agtcctcttc cgtgccggcg aagtgggatc
    21421 cgcgggcgtc ggagagatgg tcgtggactc gagcgaaatc atcaacacgc tccggggtgg
    21481 cgggataacg tcggtcgggt atgcaatcac tgaagtggtc accaagaagt caaaaccatc
    21541 cgtgagcagc ctcatcgggg ggataaaggg aaccctccgg aagagagaag cgacagaaga
    21601 gggtcttctc ggggaggatc ggacggcaaa gataatctcc cttgtgcgga gagccatgct
    21661 cgggagactc actctcccct gtgattacag cactgccgag agagcactcg tcctcgttgc
    21721 aggcccgccc gatgaactcg accggaaggg aatcgagaaa gcaaagagct gggtcgaaga
    21781 gaacatcgcg ggtgtggaag tcaggggagg tgattaccct gtcaacagca gttacgttgc
    21841 tgcagttgtt gttcttgcca cgattgccaa tgccccgagg atccgggaac tgatggatat
    21901 tgcccggaca acaaaggaag acgtggcaaa gtcccaggag agaaagccca taacacttga
    21961 tgaagagata gaaccattgt tcgagtgata gtatgcggaa tgtgtgtacg tgtgttgttg
    22021 ttcttttcct gtgcctcctt gttcagggta tagcagccat atctgtggga aatattgcca
    22081 ttactccatc cgggagcctc atttcgggcc agactcaggt caggtcgaca tttatcattg
    22141 aattcccggc cagcggggga aagacattcg atgatacgaa ttccctccag ctgtccagtg
    22201 agatggataa ccccacatgg acctattcac tggtcctcga tgaagttgaa aatccctcga
    22261 agacagaggt cggccagaac gtcaatatca acggatggct tctctcttac ccggcaaaaa
    22321 gggaactgtc catgaaggtg acgatggagg ggaccgctcc ggtagtggac ggaacgagcg
    22381 agaaaatcgt catcgcggta agggagctcg acagcaaggg gaaggcgata gcctcttccg
    22441 aggtgatcaa gaaagccctg gtcatcaacc cgtcgcaggt caaggaatca atccagcagg
    22501 ccagggaaaa actggcctcg ttacgttctg agattgatgc agcaatgatc ccaggacttg
    22561 acttatcggc tgttgaggca aaatacaatg aggcgaacac agccatccag aatgcagaca
    22621 gcaccagcga ttattcccgg gctcagagtt atctgaatac agcgattagt gctatttcgg
    22681 atgcacagac cctcctttca gaattcacta tccagaagac tctcaatgat gctgatgcca
    22741 agataggtga ggtcagttca cttatcacgg atttccgggt taacaaaagc atggggtcag
    22801 atccccgtct tacgcccatc ctgctggctc atgacaatgc agcaggtctt gtgtcggaag
    22861 caagggatgc cctctccgca aagaattatg atcaggcccg cactaaagcc acagatgctg
    22921 cagccaaagc tgacgaggcg ctggcagagg catacacact gaagcaacag gttgaatcca
    22981 acccgctgag tggcgctgcg tcgatggcag cagggatcct cgtgggtggc atggtcatta
    23041 ttgttgccgt tgtcgttatc gccattgttg ccatagtggg atacctgctc ttccgcaggc
    23101 ggcgaaaatg ggacgaactg ggctgaactc catttttgct ttttcgaatt aaccggtttt
    23161 tattttcccc cacggatttt catcgaagaa aattctctct ctttttttaa tcaaactggt
    23221 cgtttttccg tctctcacgt ccggaagaac tctaccggcc gcgaccgtgg cgatagggta
    23281 tcggggcgag gtgagaaagg tttggctttg gtaaggatct atacccgggc atgcatgccc
    23341 tattgtcatg ggtggcggca cactctcaaa aggatcaatt tccgccgggc gtcagaagag
    23401 aaaaatccca tgctgtctta aacaggaggg gaaagatctg cttttgcata gagacccggt
    23461 tttgtgaaca cgtcaatgtt gatgctaccg atttttccgt cacgtttgac atagtattcg
    23521 aagatacggt tttcgttatc gtagatagaa aaccagtaac agagcttgta ggtcttcttg
    23581 tcataacccg gcagggctgg ataacttgcc tggtcatgtg tgatcaccat gtcagggtcc
    23641 acactgaata tcgttgcctc atccacgatc tttccataga aatgcatttt gttccatcca
    23701 tccccccggt aataccaggg gagcggccag tagttttcag aagcgatgac gacagaatca
    23761 gaggcatcga tgagtttcat cacgatacgg agatcctcag agttctgcac ctgcacgatg
    23821 ggctcgttga tattgccggg ggaaaaagag acatggaatg tcatcaggat caggaaagcg
    23881 cacccggcca gggcaaagac aaccttcttt tcgctcatca ggtacatgga gacaagtatg
    23941 gcggggagga gctggtggat gatcagccat ggcacctttt caccgatata ggcataagcg
    24001 gctaccgatg caacgaacca ggtgatgcag aagaggaaga aaagttcccg ttttgaatga
    24061 aaaccgggta cgcgattttt gttttgttta aataagtctt tgtaagaacc atttgtctct
    24121 tctacgtttg gaccggtcaa ttggtcatgg actacttcat cggggacttc atttctcaaa
    24181 cgatgcactt tccagtcatg gatacggttt tgaacacgtg caaccaggcc cgggaacggg
    24241 ttgtgacggt cagcgaactg gaccatgcca aagagtgcaa ggatgaagat cgggacctcg
    24301 tagaggagaa ataacacgat gtaaaaaaac catggaccac agatacggca ctgtccgtgc
    24361 attgcggccc agtgcgtata ggccttgatt acgcctgtct cgagaatctc gggatgaaca
    24421 ccgaacgaag agtaaaagag ggccatgacg ctgatggaga caaggattgc caggacgcca
    24481 tcacgtatcc acgtgcgggg gaatgctaca tcccgtctcc agaggagata gatcccaaat
    24541 acgatcacaa cgacaaggaa cagtggcatg tcctccttga gacacatccc gcctccggcc
    24601 gcaagaccgg cgaggacagc gtaaccaatt ttaccccgtt ccaagtacgc aagcagcgcg
    24661 acaaggagaa gaaccgagaa gaagagctgg aaggtatcgt gccgcaggaa acgggagaag
    24721 taaacgagat cgggagatat ggcaatgaaa agtgcggcta cgagtgcctg ccgcgtgtcc
    24781 aggtaaccca ggcgataaat cgcatagaca agcgggacaa ttgcagctcc gaagagtgcc
    24841 ggaaggatcc gggcgacggc atctgattgt cctaaaagaa aaaacatccc ggccgtaata
    24901 taatacagga aaggaccgtg gtacatcggg tcgtagatat acgtcccctt tgtcagaagc
    24961 tcgtaggaaa accaggcgtg gatcgcctcg tcatggtgca gcagcttgaa gtcaagaaat
    25021 aagagacgca ggagaagggc gatgataaaa accaataaaa atagtccgtt aaaagaaaaa
    25081 accggccgga ttttctggat aacgccggct gcggtcaagc cgctccctca gctttccaga
    25141 acaatctcga taccgatatc cttggggacc tgtgtacgca tcagctggcg gagtgctctc
    25201 tcatcggcat cgatatcgat gagtctcttg tgaaccctca tctgccagcg gtcccacgtg
    25261 gcggtgcctt ctccgtcagg gctcttgcga atggggatga ccaggcgctt cgtcggcagc
    25321 ggaatcggac cagccagatt cacgcccgtg cgctccgcga tctcgcggat gc
//
LOCUS       DAOOJU010000024        24334 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2132_length_24334_cov_14.826599, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000024 DAOOJU010000000
VERSION     DAOOJU010000024.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 24334)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 24334)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24334
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2132_length_24334_cov_14.826599"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..286
                     /locus_tag="PK679_06845"
     CDS             <1..286
                     /locus_tag="PK679_06845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55708.1"
                     /translation="PMTILLRCRLCKGTGEIPNEQFRICKELKSHDIKKYFHMPTEDD
                     VSSDDAVTPDACNGIPEKVQCPVCEGAGTVEFDEDEWELRIVADEESAEE"
     gene            complement(722..2338)
                     /locus_tag="PK679_06850"
     CDS             complement(722..2338)
                     /locus_tag="PK679_06850"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HPC55709.1"
                     /translation="MHPIYVIGHRQPDTDSVASVMGYAEFCNRRGNETCIPAVCGPLS
                     AETRFALSALGLEPPVLVESVEPCVADIPALSLQRAPAGMPTIDVAAMMDEYDVRNIP
                     IVDDDGRLLGLVSEHGLARAYVTPRIEKPLTIGPITVETLARILGATICHEGAAVVHG
                     NVSIVIDALHVALSRLSSRDIAVVGDNEPTQLALVSAGIAVLVVAEGAPVSGRVCEAA
                     RERGTTLLSTPLDAFSVGRMMHLSLPAGRFVATDVPVVGPEDTIAYAKRLVTDSKYRA
                     ACVVGKDGVLVGMISRNTFLEEVQKRVILLDHNEYSQAVEGIESAEILEVIDHHRLGA
                     ITTLKPVRFQNEPVGSTSTIIARKFMESGSPPTPPIAGMLLAGILSDTLVLKMSTTTP
                     EDVSAAEYLAGIAGMDIQEFGTRLIQNGMDLDKTPLDQLLSRDTKRYTLFGKDVIIAQ
                     VMTSSREYAAEHAGEIRAELEKQRKSRGADLYLVLFSDIIGNCSDLFAAGDTATLRAL
                     GYMDQPIILPGVMSRKKDFLPAFGGKLRDL"
     gene            2600..5407
                     /gene="uvrA"
                     /locus_tag="PK679_06855"
     CDS             2600..5407
                     /gene="uvrA"
                     /locus_tag="PK679_06855"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HPC55710.1"
                     /translation="MKKLIIRGARQHNLKNISVELPRDKFIVITGLSGSGKSTLAFDT
                     IYAEGQRRYVESLSAYARQFLGLMHKPDVDTIIGLSPAISIEQKSTSKNPRSTVGTVT
                     EIYDYLRLLFARIGVPYCPVHNTRIEAQSPERIADRIQSDMGGTVTILAPVVRQKKGT
                     YQQLIRDLNREGYTRVRINGEIHRTDEEITLERYRKHDIDVVVDRLDTQDRSRLTEAC
                     ENALKKSQGLVIALSQEGEERIFSSLLACPVCGLTFEELQPRMFSFNSPFGACEECNG
                     LGIKMEFDPDLIIPDRSKSIAEGAVALYRNYLDGYRNQYLGAVARHYGFSVLTPIGDL
                     SPEQYNILMYGSPDRIRFSLNTRNGNAQWSHTGEWEGLIPQSERLYHQTQSEYRKREL
                     EKFMRVSECPRCRGRRLKEKVLSVRIAGMSIVDITDMPVSRAIGFFSHLDLTDREREI
                     SRQILKEIMARLDFLEKVGLGYLTLSRSAGSLSGGEAQRIRLATQIGSNLMGVLYVLD
                     EPSIGLHQRDNQKLIDTLRRLRDLGNTLIVVEHDEDTIRNADWVVDMGPGAGVHGGHI
                     VAEGTPEQIAENPHSLTGQYLAGTLRIDVPKERRKSDKFLHITGCRENNLKEIDVHIP
                     LGVLTVVTGVSGSGKSTLVYDTLYPALQKELFRSRTSPGKYTGLAFDAPVDKVIVIDQ
                     SPIGKTPRSNPATYTKVFDEIRRVFAETKEAKARGYKPGRFSFNLKGGRCEACEGDGL
                     IKIEMNFLPDVYIECEECKGTRYNRETLEVRYRGKTIAEVLDMTVEENLALFANIPSI
                     RHKLETLAAVGLGYIKLGQSSTTLSGGEAQRIKLTRELAKRGTGRTIYLLDEPTTGLH
                     FHDVKKLIAVLNELVDKGNTVVVIEHNLDVIKSADYIIDLGPEGGDEGGYVVATGTPE
                     EVARNPASHTGKFLQKMLARA"
     gene            5404..6957
                     /gene="uvrC"
                     /locus_tag="PK679_06860"
     CDS             5404..6957
                     /gene="uvrC"
                     /locus_tag="PK679_06860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HPC55711.1"
                     /translation="MTAPPVSLPDAPGCYIFRDKSGSVIYVGKAKNLKKRVASYFSGR
                     DHDRKTARMVGCIADIDYIVTKNEVEALVLENSLIKANQPRFNINLRDAKQYAFIHLT
                     DEDFPRICIARRMGDRGSFFGPFTSAAERDHVLAVVKKTFRLRSCRTLRKRGCLRASL
                     GTCSAPCRGMIGKEEYAQAVRQASAVLKGNAPDLIRTLRAEMEARARECDFERAILIR
                     DQIAAIENLSIRQDVARKRDTDEDIINFIVHEGHVYLMIFSVSRGVLVNKKEFIFEGE
                     GDFLEEFLVQYYSDILPPGELVLPLHPGEEMEEFLSLRKGRRVIITVPRIGAKKRLLS
                     LVRTNIEVAHFGEEMKLEELREKLGLETVPRVIECFDISHLSGTEVVGSMVQFRDGRP
                     DKRNYRRFRIRTVEGIDDPAAIGEVVERRYRRQVKEGKELPDLVIVDGGITQLRAALS
                     RMRDIGVDIPLVALAKKEEKVYVPGSSHPLPVRKNEKASLFLQEIRDEAHRFAISYHR
                     LLRSRKVVS"
     gene            6954..8885
                     /gene="uvrB"
                     /locus_tag="PK679_06865"
     CDS             6954..8885
                     /gene="uvrB"
                     /locus_tag="PK679_06865"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HPC55712.1"
                     /translation="MSRFSLKATFSPRGSQPEAIAKLVSGIEAGHRFQTLLGVTGSGK
                     TFTMANVIERVQRPTLVIAHNKTLAAQLWNEFREFFPDNRVEYFVSYYDYYQPESYIP
                     QKDQYIEKDAQINPRIEMMRLSATASLLSRRDTIVVASVSCIYGLGRPEHFRDLGFEV
                     RVGDRISRREIIEKLISGLYERNDLELMPGRFRVRGDTIDIIPGYFHDIIRIELFGDE
                     VDRILEVEKASGKTRESHRYFHVYPARHYVIPGDVQKRAIASIRKELDERLPELGMLE
                     AHRLEQRTLYDLEMIEETGSCKGIENYSRHFDFRKPGERPYCLLDYFPPDFLMFIDES
                     HQTIPQLHGMYHGDRSRKKALVDYGFRLPSAYDNRPLMFREFEQFMRQVIFVSATPGD
                     YELSCSQQVVEQIIRPTGLVDPEVIVRGTAGQVEDVIREIHATVGRGDRVLLTTLTKR
                     LAEELTDYLAEKGIRTRYLHSEIDTLERTEIIRELRLGTFDVLVGINLLREGLDIPEV
                     GFIGILDADKEGFLRDARSLIQIIGRAARNVNSRVVLYADTITGSIQAAVAETERRRT
                     LQKEYNALHGIVPQTIRKPVPKKEVDIRDTRHVPKAEIPNLLVELEARMFQAAERLEF
                     EEAIRIRDTIRELKEKVGV"
     gene            complement(9032..13201)
                     /locus_tag="PK679_06870"
     CDS             complement(9032..13201)
                     /locus_tag="PK679_06870"
                     /inference="COORDINATES: protein motif:HMM:NF013955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55713.1"
                     /translation="MTSERGLQIVVTILVFLALVIPASATLAITGIDPSSGLNTEDDL
                     YISNLSGTDFPGQGEATVALRMSGEENITGRYVTVVSPSRITCVFDLTGRKAGLWDVV
                     VTNETSGESVTLEKAFTIENPSPEITAISPSFGENDDWVDITNLAGSNFLPNVTVNLT
                     RGATIIPGENVTRVSSSQITCRFNITFAEPGFYNVTVTNEDGKYKTLINGFEVRYPRP
                     VVTAIYPSSGTNDMVVGITNLSGSGFMPGANVSLRRSGHDDIPTINGAIVESSGKILC
                     FFDLNGAHVGKWDVVVRNLDGQNGTLPSGFTIYYPDAPSVTGIVPATGQNTGNILANV
                     TGSGFHENPAVLLAKGTQTVAGSVLSVSGTDIGVRFNLTGVPAGKYNLTVTNEDGQGA
                     TKVEAFTVTNPPPTVTDVDPSSALNTGDYVLLDITGTGFLSGATVTFTRGSTTFSESS
                     TYVNSTHLRCTVSFSGKEAGEYNVTVTNTDGLSGTWEGVFTIQNPAPVVHAISPHEGQ
                     NTGLLENVVVTGENFLPGAGVNLTRSGEYPITGSPVTWINATALSCTFDLTGKKAGAW
                     TVVVANPDGRTSIEPVVFTITNPPPNPQDIVPDSGPNNGPVGITGLTGSGFLPNATVK
                     LTREGENDIPGTGVDINVTSQTIMCFFNLNGARVGYWNVVVRNDDGQSGTLENAFFVR
                     YPAAPAVLAIEPASGPNDGPITISNLSGSGFHPNATVRLTRASLPDIIATNVTVVDSG
                     KITCTLNLAGAVPGSWDVIVTNDDGQAGEISGGFEVRYPAPTVTGITPAKGNNNQIVP
                     FTLTGSNFRSGATVKLARASHTDIVATGVSLINSSALSGSFNLNGMDVGEWDLVVTNN
                     DGQSATHVNGFTIEYPNPVVSSILPNKGSNDGPLQITAVKGNYFREGATVTLTRTGLA
                     PIEATDVHVINATTLNCTVNLQGRTIGLWNVVVTNDDGKSGQLANGFQILPPPPVPDF
                     SASPVYGTVPLTVRFTDLTTNNPTAWIWDFGDGSQSGILDRNPVHTYNAVGTYNVTLT
                     VFNTGAPEGRSITKTSYITVVRTPVADFTATPTSGNAPLLVQFTDTSMGNPTGWVWTF
                     GDGSMSTQQNPYHLYTSPGVYSVTLSVRNSAGSNAITKEGLITVRALPVADFSANRTS
                     GPAPLVVKFTDGSSGGPTSWNWNFGDGTSSTEQNPVHQYNVPGVYTVSLTAANDVGTA
                     EKTKTGYITVGERLTAAFTYTTSNPENLAPLTVAFMDGSGDSPTMWAWNFGDGHLTTE
                     KNPIHTYTKAGNYTVTLTVSDGFASSSTSKTIEVKPRLIADFKVEPSTGSAPLKVKLI
                     DQTIGTPNSWRWVIVRDALNMTVFDPGQATETYTFNEPGSYDVILTVSDAYGNTESVR
                     KDSVVEVLPFP"
     gene            complement(13676..14713)
                     /locus_tag="PK679_06875"
     CDS             complement(13676..14713)
                     /locus_tag="PK679_06875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HPC55714.1"
                     /translation="MVMELLTKLSNAHGVSGSEDSIAAIVKRELRRYVDEISEDRMGN
                     IIAVKKGGKFRVMLAAHADEIGLMVKSIDEKGFIRFVALGGWFAPTLYNQRVILHGTK
                     GRVTGVLGGKPPHKMDEEERKKGVKIEDMFIDVGARSREEAVELGISVGTPITIDRQV
                     ATLAHGRITGKAFDNRVGVALLIKTMQQVKSPHTLYAVFTVQEEVGLKGAKTSAYTIN
                     PDCAIATDVTIPGDHPGIDQKDVPVEMGKGPIITIADASGRGLIASRPMVRWLADTAE
                     SCSIPVQFEVGSGGTTDATAIHLERGGIPSTTLSIASRYIHSPVEVVDISDIENGVRL
                     LVEALRTKPGF"
     gene            complement(14720..15829)
                     /locus_tag="PK679_06880"
     CDS             complement(14720..15829)
                     /locus_tag="PK679_06880"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HPC55715.1"
                     /translation="MKKARCAERCLGIEISGIRRLFESAGPDSINLGLGQPDFDTPGH
                     IKEGAIAAIREGKTGYTPNMGIPELREALSRKFKNENDLSYAPDQIIVTAGASEALHI
                     IMHALVGQGDRVLYADPGFVSYGALAILAGGRPQGVPLDARMHIDVEKAKETIDGARL
                     FVLNSPGNPTGAVEPKENIRALVEYANDRGVTVVSDEVYEHFIYGPKHWSAALFGEDV
                     ITVNAASKTYAMTGWRLGYLAGPKEYIEQALKVHQYCQACATSISQYAALAAYNGPQD
                     CVAAMREEYRARRDYFYGELTRMGFSFPRPEGAFYMFVPFGEDLTAKILKSGVVIVPG
                     NAFGCNAPGYARMSYATSRSTLEAAVERIRKAMEG"
     gene            complement(15844..16443)
                     /gene="hxlB"
                     /locus_tag="PK679_06885"
     CDS             complement(15844..16443)
                     /gene="hxlB"
                     /locus_tag="PK679_06885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HPC55716.1"
                     /translation="MAAQRVQEMMRLMARRITAIAGSLSDEEVEEFIDEILHARRIYV
                     MGAGRSGLVAKAFAMRLMHLGLSSYVVGETITPAMSPGDLVVVFSGSGKTKTVADIAE
                     TAKEIGGRVALITSDRDSRIGRIADTIVIIEHHRDEVRDEGAEFEIRQVMGEHKSFAP
                     LGTLFETAAMVFADAVISRLMEITKTDEKELKNRHANIE"
     gene            complement(16591..18102)
                     /locus_tag="PK679_06890"
     CDS             complement(16591..18102)
                     /locus_tag="PK679_06890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HPC55717.1"
                     /translation="MDTEKYSFIARVPDRPGALHPAVDVISRNGGNINRIQFDRRIDP
                     CTVFFEVTSGPGAREEIARGLRELGYLQTALKPQSFLKLSVHIPHTPGALSDFLRFTT
                     AHKANIAQIDFDDRGSRPHILTVSLNLGEEEEVTKLLDDLKSRYRMEVLDYDTSGKYL
                     DDTVFYLRFAQSLRDIVGESEDAFLLSLLGDINHVAQELMKRGKDPKTVFESVEKTGR
                     TLKSTCGPGFYADLQNIRLAPDLLLVCIQPPCGGSVFLLDSPGECVMVDTGYGIYYPD
                     ICQIIRREVPGALDRLSRIIITHADADHCGAGGLFTVPCLMHAGTRDIILVSNRAYGS
                     RNHESILEEVYTSLINIFSRFSPPRDIVLFPPAGDERVGAFPVIGEVRAGRYRFLVLE
                     GLGGHLFGQIYLYSRDLGVFFSADTAINFDHLTPDRAQYNTLAVNLVTSVNVDSEKAR
                     EERQEIFGIVRQTNGSYPGGRSECLVCGGHGPVSLLQGTRLVPASPVRRVPGE"
     gene            complement(18189..18497)
                     /locus_tag="PK679_06895"
     CDS             complement(18189..18497)
                     /locus_tag="PK679_06895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55718.1"
                     /translation="MDFREVLTGGGEPLDIYDDIVPVLEDVCLLPWKVEEIYRKASSY
                     DDAHLDRLRFALVRLQVYADIHRNEDMEKAQAIKYASVVLEKVIFGSLMLGHEEMERD
                     "
     gene            complement(18498..19388)
                     /locus_tag="PK679_06900"
     CDS             complement(18498..19388)
                     /locus_tag="PK679_06900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HPC55719.1"
                     /translation="MTEEAKKTPEECNGVCEGCPSAKQCDSDKKTSKGKGLPPKAEID
                     VDHVILVLSGKGGVGKSTVAVNLSFALSAHGYSVGLLDLDIHGPNVPKMLGLEGQHLT
                     TLGNMIQPVRVTGNLAVVSMAFLLPDKSTPVIWRGPMKMSAISQFLSEVDWGHLDFLV
                     VDLPPGTGDEALSIVQLAPNVRGAVIVTTPQEVATMDAMKAIKFVEQLGVPVVGIVEN
                     MSGLVCPHCKQEIDLFGKGGGEAVARELGVPFLGSIPLDPEMRKAGDEGKPFIIRSHD
                     NPTWKSVDKVMEELVKVVEG"
     gene            complement(19470..19895)
                     /locus_tag="PK679_06905"
     CDS             complement(19470..19895)
                     /locus_tag="PK679_06905"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HPC55720.1"
                     /translation="MEAVITCYTDGASRGNPGPAAAGFVLLDSDGRVLEKKAVFLGKK
                     TNNEAEYHAVINALAAAKKHGAHRVRICSDSQLVIRQLRGEYRVNKPGLRELCARVRL
                     CEQGYSSVEYVSTGRDHPWIQEADRLCNGVLNAEISRSD"
     gene            19956..20408
                     /locus_tag="PK679_06910"
     CDS             19956..20408
                     /locus_tag="PK679_06910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HPC55721.1"
                     /translation="MEKLDVSLGFLEFPPVHTCDGEDLSPLIRIGNPRGQFLALMAIN
                     PFIPSCCSFSTWIAWNIPVTGIIPSGIPRDPVVSDPVSAVQGTNDWGTIGYRGPCPRP
                     GTTHRVTFKVWALDGPVPVPPGSRKADLVAGMRGHVLAYGDTMALYSR"
     gene            20464..21207
                     /locus_tag="PK679_06915"
     CDS             20464..21207
                     /locus_tag="PK679_06915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55722.1"
                     /translation="MEKRDIAILMLALAGMVILAGVVKPLLTGQSIDLSLPPLPGILP
                     AEPTPVPTPETHIPRVTTAPPTRETPPPTPTWSGKPQTLGYVALVTPSPTPSFSILPD
                     TSAPPEKLLTYATIQSHAGGITQAMAMPFPYWELHYTVDPWETTFVGETSSKMAGQAD
                     YFASEIFPSFSIEVRDAADGSLVRKIEPPGGLNAKLWKENKENDPRPWIEKFYEGTTT
                     RSYYFVVNTHMIHSYKMEVKVPERYLGKY"
     gene            complement(21295..21678)
                     /locus_tag="PK679_06920"
     CDS             complement(21295..21678)
                     /locus_tag="PK679_06920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-5A"
                     /protein_id="HPC55723.1"
                     /translation="MKEQTEIGKLKEGRYMVIDDEPCKILGISVSKPGKHGAAKARID
                     AVGLFDGVKRSIVQPVSAKTYVPVVERKSGQVITISGQIATLMDMKEFNNFEIEVPPD
                     KMDKIEVGKEVQYIEALGKRKLDIE"
     gene            21767..22543
                     /locus_tag="PK679_06925"
     CDS             21767..22543
                     /locus_tag="PK679_06925"
                     /EC_number="3.1.3.11"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     fructose-bisphosphatase/inositol-phosphate phosphatase"
                     /protein_id="HPC55724.1"
                     /translation="MEFLEACHLLARDIRGAISGLVGTEKGGKNLCIGADGTPTKEID
                     RVAEDCVIAFLEKHPLCRTLISEEAGRVSLGGEKGTIFLDPIDGTYNAVAGIPFYALS
                     VAYAEDGIVLKGFVHDLAGGETFTAIRGQGAFLDGRPISVSRISRLDECAMSVYGRKF
                     DPRRVMHIGQKIRRWRLLGASALELSYIGCGRIDGFIDLRGTLRVTDAAAGMLVCTEA
                     GGMVSDLEGRPIRFPDEVTIGRCMVATNGVLHHKVIEYLR"
     gene            22563..23375
                     /locus_tag="PK679_06930"
     CDS             22563..23375
                     /locus_tag="PK679_06930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HPC55725.1"
                     /translation="MRIALVSRVDDQRAISFTRDLGDTIGSLGHEVSFEPATARVLRS
                     DNLWPFDGSVDLAIIVGGDGTILHTIQQMDHKVPVIGVNWGEVGFLADLEPDEAIPFI
                     RGLKPGFPTEPRMRVALKSGETVLGEALNEALIVTSRPAKMLRFVIVVDGIEAESFRA
                     DGLLVSTPTGSTAYAMSAGGPIVDPRIEGFLLVPLAPYMLSSRPHLISNDRSVRISLE
                     SAKPATLVIDGQKTIELGNEQLLEVTQAEQPALFVDAHKNFFKKVDHKLRHL"
     gene            23441..24172
                     /locus_tag="PK679_06935"
     CDS             23441..24172
                     /locus_tag="PK679_06935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004075813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HPC55726.1"
                     /translation="MEVRRMDATIMKEMDYREASAVLVKSLGLKNSPVAIRLAMGKEE
                     IPEGMEKLDGTIRHCQMVNLARKEGRVFYATVENHECMGGAWALGLRQITETLKNGQF
                     YFKLGKFESTAACKRTIDRIPHVESGSTYATLYAPLEKTNFSPHLILVIAEARAMLKL
                     AQATLFRLGGRITSEFSGIQSVCADACAQTFLSGKANYSLGCDGSRKFSGIEDGEMVM
                     GFPVEMLPEIVDAVRIVTAAPGSKK"
BASE COUNT         5093 a         7084 c         6943 g         5214 t
ORIGIN      
        1 acccatgacc atcctcctcc gctgccgcct ctgcaaggga acgggtgaaa tcccaaacga
       61 gcagttcagg atctgcaagg aactcaagtc gcacgacatc aagaagtact tccatatgcc
      121 gacggaagac gatgtttctt cggatgatgc cgttaccccg gatgcatgca acggtatccc
      181 ggagaaggtc cagtgccccg tctgcgaggg agcagggact gtcgagttcg acgaggatga
      241 atgggaactc aggatcgtcg ccgatgagga atccgcggaa gaatgacctt tgaacctttt
      301 tactctccat cgcacaaagg tcccgggaaa tgattggtct ggataataac accctcgatc
      361 ccgtctatct cactatttag cccttttcgg ttgtgagtgg acagtaagag aaaaaggggg
      421 gatttgcccc gcgtttatca ccccctggaa taatcccagt cactcaaaac cctcaccccg
      481 gcagcttttt ttgggatccg aaatgcactt cctgatgaca attctccttt ttatcaccaa
      541 tacgtaactg cgcgaggctg tatgttcaaa taattctcac ctgcattata tgatgaaaag
      601 gtataacaag cggggatacg caaagtgcct gattgcattc ttcacgaaaa aaccgtgact
      661 ttttttgggg ggacgctcca tcggggatcc aatgttaagg gagtatccgg aaaggggatt
      721 ttcaaaggtc ccggagtttt cccccgaatg cagggaggaa atccttcttc cgggacatga
      781 ccccgggcaa aatgatgggc tgatccatat agccgagagc ccttaaggtt gccgtgtcac
      841 cggccgcaaa cagatcgctg cagttcccga tgatatccga aaagaggacc aggtaaaggt
      901 ctgctccccg gctcttccgt tgtttctcga gctcggcccg gatctcgccg gcatgctctg
      961 cggcatactc ccgcgagctg gtcatcacct gggcaatgat gacgtctttt ccaaacaggg
     1021 tatagcgctt ggtgtcccgg gaaaggagct ggtcgagggg ggtcttgtca aggtccatgc
     1081 cgttctggat gagtctcgtc ccgaattcct ggatatccat gcctgctatg ccggcgaggt
     1141 attctgcagc ggagacgtcc tcgggagtcg ttgtcgacat cttcaggaca agggtatcgg
     1201 agagtatccc ggcaaggagc atgccggcaa tcggtggcgt cggcgggctc ccggattcca
     1261 tgaacttgcg cgcgatgatc gtggacgtgg agccgaccgg ctcgttctgg aaccgcaccg
     1321 gttttaaggt cgtgatcgca ccgagccggt ggtggtcaat gacttcgaga atctctgccg
     1381 actcgatccc ctcgacggcc tgggagtact cgttgtggtc aaggaggatg acgcgctttt
     1441 gcacctcctc gaggaacgtg ttccgcgata tcatcccgac taggacgccg tcctttccaa
     1501 cgacacatgc tgcacggtac ttcgagtcag tcacgagcct ctttgcatat gcgattgtgt
     1561 cctccggtcc gacaaccggg acatcggtgg caacgaacct tcctgccggc agggagagat
     1621 gcatcattct gccgaccgag aaggcatcga gcggggtgga gagcagggtc gtcccgcgtt
     1681 cccgggcggc ctcgcagacc ctcccgctca cgggggcacc ttcggcaacg accaggaccg
     1741 ctatcccggc ggaaacaagg gccagctggg taggctcgtt gtccccgaca accgcgatat
     1801 cccgggacga aagccgggag agcgcgacgt ggagcgcatc gatgacgatg gagacgtttc
     1861 cgtggaccac ggcagctccc tcgtggcaga ttgtcgcgcc aaggatgcgg gcgagggttt
     1921 cgaccgttat cggcccgatg gtgaggggct tttcgatccg tggagtgacg tatgcccggg
     1981 cgaggccgtg ctcggagacg agcccgagga gccggccgtc atcgtcaacg atggggatgt
     2041 tccgcacgtc gtactcgtcc atcatggccg ccacgtcgat cgtgggcatc ccggccgggg
     2101 cacgctggag ggagagggcc gggatgtcgg caacacacgg ctcgacgctc tcgacgagca
     2161 cgggtggctc aaggccaagc gcggagaggg caaaacgggt ctctgcagag agagggccgc
     2221 agacggccgg aatgcaggtc tcattccccc ggcggttgca gaattccgcg tatcccatca
     2281 cgctggcaac gctgtcggtg tccggctgcc tgtgcccgat cacgtagatt ggatgcattc
     2341 ttcctttccg taaatgggtt ttttcaattc ttatcactgc gggctgcaga gagaaaaatc
     2401 ccttcatccc tggtttttgg atccacagat atgaaactta catggggctt aataaggtat
     2461 attaggttcc atccgggaga gcgctccttt cccgataccg cgacatttcc ctgcccttgg
     2521 gggatacggt gtgtttcccc tgctacccgg aggctcaccc ctatattgtt caacatccac
     2581 atgatagact cgacaccaga tgaagaagct catcatcagg ggcgcgcgac agcataacct
     2641 caagaacatc tccgtggaac tgccgcgcga caagttcatc gtgattacgg gtctctcggg
     2701 ctccggcaag tcgactcttg ccttcgatac catatacgcc gaggggcagc gccggtacgt
     2761 cgagtcactc tctgcctatg cccgccagtt cctgggcctg atgcacaagc ccgatgttga
     2821 caccatcatc gggctctcgc cggcaatctc gatcgagcag aagagcacga gcaaaaaccc
     2881 gcgcagcacg gtcggaacgg tgaccgagat ctatgattac ctgcgcctcc tgttcgcccg
     2941 gatcggtgtt ccctactgcc cggtgcacaa tacacgtatc gaggcacaat ccccggagcg
     3001 gatcgcggac aggatccagt ccgatatggg ggggacggtc actatcctcg ctcctgttgt
     3061 gcggcagaag aaggggacct accagcagct catcagggac ttgaacaggg agggctacac
     3121 ccgggtgcgc atcaacggcg agatccatcg caccgacgag gagatcacgc tcgagcggta
     3181 caggaagcac gatatcgacg tcgttgtcga ccggctggat acacaggacc gttcccgcct
     3241 gaccgaggcc tgcgagaatg ccctgaaaaa gtcccaggga ctcgttatcg ccctctctca
     3301 ggagggggag gagcgcatct tctcgtccct ccttgcctgt cccgtctgcg gcctgacgtt
     3361 cgaggaactc cagccccgga tgttctcctt caacagcccg ttcggggcct gcgaggagtg
     3421 caacgggctc gggatcaaga tggagtttga ccctgacctc atcatacccg accgatccaa
     3481 atcgatcgcg gagggggcag tcgccctcta ccggaactac ctcgacgggt accgcaacca
     3541 gtaccttggt gcagtcgccc gccactacgg cttctctgtc ctgacaccca taggtgacct
     3601 ctcccccgaa cagtacaaca tcctcatgta cggctccccg gaccgcatcc gcttctccct
     3661 gaacacgcgg aacggaaatg cccagtggtc ccacacaggg gaatgggaag gcctcatccc
     3721 ccaatccgag cgcctctacc accagaccca gtcggaatac aggaagcggg aactcgaaaa
     3781 gttcatgcgg gtatcggaat gtccccggtg ccggggcaga cgcctgaagg aaaaggtcct
     3841 ttcggtccgg atcgcgggaa tgtccatcgt ggacatcacg gacatgccgg tcagcagggc
     3901 aatcgggttc ttctcgcacc ttgacctgac cgacagggaa cgggagatat cgcgccagat
     3961 cctcaaggaa atcatggccc gcctcgattt cctcgagaag gtcggcctcg ggtacctcac
     4021 cctgtcccgg agcgcaggca gcctctcggg gggagaagcc cagagaatca ggctcgcaac
     4081 gcagatcggt tcgaacctga tgggtgtcct ctacgtcctc gacgaaccct ccatcgggct
     4141 ccaccagcgg gacaaccaga agctgatcga cacgctccgc cggctcaggg acctgggtaa
     4201 taccctgatc gtcgtggaac acgacgagga cacgatcagg aacgcagact gggtcgtgga
     4261 tatggggccc ggcgcgggag tccacggggg ccatatcgtc gccgagggta caccggaaca
     4321 gatagcggaa aatccccact ctctcacggg gcaatacctt gccggaaccc tgcggataga
     4381 cgtcccgaaa gagaggagaa agagcgataa gttcctgcac atcacggggt gccgggagaa
     4441 caatctcaag gagattgatg ttcatatccc ccttggcgtc ctcacggttg tcaccggtgt
     4501 ctcgggttcc gggaagtcaa ccctcgtgta tgacactctt tatccggcgc tccagaagga
     4561 actcttccgg tcccgcacga gcccgggaaa gtacaccggt cttgccttcg atgccccggt
     4621 tgacaaggtc attgtcattg accagagccc gatcgggaag acgccgcgga gcaaccccgc
     4681 gacgtacacg aaggtctttg acgagatccg cagggtcttt gccgaaacga aagaggcaaa
     4741 agcgaggggc tacaagccgg gcaggttctc cttcaacctg aagggcgggc ggtgcgaggc
     4801 ctgcgaggga gacgggctga tcaagatcga gatgaacttc ctgcccgacg tgtatatcga
     4861 atgcgaggag tgcaagggaa cgaggtacaa ccgggaaacc ctcgaggtga ggtacagggg
     4921 aaagacgatc gccgaggtgc tggacatgac cgtggaagaa aacctcgcgc tctttgccaa
     4981 tatcccctcc atccggcaca agctcgagac gctcgctgcc gttggcctcg ggtacatcaa
     5041 gcttggccag agctcgacca ccctctccgg gggggaggcc cagcgcatca agctcacgcg
     5101 ggagcttgca aagcggggta cggggcggac catctacctg ctcgacgagc cgacaaccgg
     5161 cctccacttc catgacgtga aaaagctgat agccgtcctg aacgaactcg tggacaaggg
     5221 aaacaccgtg gtggtcatcg agcataatct cgacgtgata aagtccgccg actacatcat
     5281 cgatctcggt cccgagggtg gcgacgaggg gggatacgtt gtcgcgaccg gcactcccga
     5341 agaggtcgcc cggaaccctg cgagccatac gggaaagttc ctccaaaaga tgctggcacg
     5401 cgcatgaccg ctcctcccgt gtccctgcct gacgcccccg gctgctacat cttccgggac
     5461 aaatcgggtt ccgtcatcta cgtgggaaaa gcaaagaacc tcaaaaagcg tgttgcaagt
     5521 tacttctcgg gccgcgacca cgaccggaag actgcccgga tggtcgggtg catcgcggac
     5581 atcgactaca tcgtcacgaa gaacgaggtc gaggcactcg tgctcgaaaa cagcctgatc
     5641 aaggcaaacc agccacgctt caacatcaac ctccgggacg caaagcagta cgccttcatc
     5701 cacctcacgg acgaggattt cccgcggatc tgcatcgccc gccgcatggg agaccggggc
     5761 tcattcttcg gcccgttcac ctctgccgcg gagagggacc acgtccttgc ggtcgtcaaa
     5821 aagacattcc ggctccggag ctgccgcacg ctccgcaaaa gggggtgcct ccgggcatcc
     5881 ctcgggacgt gcagtgcacc ctgccggggc atgatcggaa aagaggagta cgcccaggcg
     5941 gtccggcagg catctgcagt attgaagggg aatgcccccg atctgatcag gaccctgcgg
     6001 gccgagatgg aagcgagggc acgggagtgt gacttcgaac gggcaatcct gatccgggac
     6061 cagatagcag ccatcgagaa cctctccatc cgtcaggacg tcgcgaggaa gagggatacc
     6121 gacgaagaca tcatcaattt catcgtgcac gaagggcacg tctacctcat gatcttctcc
     6181 gtcagcaggg gagtactggt caacaagaag gagttcatct tcgaaggaga gggggacttt
     6241 ctggaagaat tccttgtcca gtactattcc gatatcctcc ctcccggtga actcgtcctc
     6301 cccctgcatc ccggcgaaga aatggaagag ttcctctccc tccggaaggg caggagggta
     6361 ataatcactg ttccccgtat cggcgcaaag aaacgcctcc tctccctcgt ccggacaaac
     6421 atcgaggtcg ctcattttgg agaggagatg aaactcgagg aactccggga gaagctgggg
     6481 ctcgaaactg tcccccgggt catcgagtgc ttcgatatct cgcacctttc gggaactgaa
     6541 gtggttgggt ccatggtcca gttccgggac ggacgccctg acaagagaaa ttacaggcgt
     6601 ttccgcatca ggaccgtgga agggatcgac gatccggctg ccattggcga ggtcgtggag
     6661 aggaggtacc gccggcaggt aaaggaagga aaggaactcc ctgatcttgt catcgtcgac
     6721 ggcgggataa cccagttgcg agcggcactc tcccgcatgc gggatattgg cgtggatatc
     6781 ccccttgttg cccttgccaa gaaggaagag aaggtctacg tcccgggctc ttcccatccc
     6841 ctcccggtga ggaaaaacga aaaggcatcc ctcttcctcc aggagatccg ggatgaggcg
     6901 caccggttcg ccatctccta ccaccgtctt ctccggtcca ggaaggtggt gtcatgagcc
     6961 ggttctccct gaaggcaacg ttttctcccc gcggttcaca gccggaagca atcgcgaagc
     7021 tcgtgtccgg catcgaagcc ggccacaggt tccagacgct ccttggtgtc acgggttcgg
     7081 gcaagacgtt cacgatggca aacgttatcg agcgggtcca gcgaccgaca ctcgttattg
     7141 cccacaacaa gaccctcgcg gcccagctct ggaacgagtt ccgggagttc ttcccggaca
     7201 accgggtgga gtacttcgtc tcctactacg actattacca gcccgagtcc tacatccccc
     7261 agaaagacca gtacatcgag aaggatgcgc agatcaaccc ccgtatcgag atgatgcggt
     7321 tgtctgcaac cgcgtcgctc ctgtcgcggc gggacacgat cgtcgtcgct tctgtctcct
     7381 gcatttacgg tctcggcagg ccggagcact tccgggatct tggtttcgag gtcagggtag
     7441 gggacaggat ctcacgcagg gagattatcg agaagcttat ttccgggctc tacgagagga
     7501 acgacctcga gctgatgccc gggcggttca gggtccgcgg ggataccatt gacattattc
     7561 cgggttactt ccacgacatc atcaggatcg agctcttcgg cgacgaggtg gaccgtatcc
     7621 tcgaggtgga aaaggcgtcc ggaaagacgc gggagagcca ccggtacttc cacgtctatc
     7681 ccgcccgcca ctacgtcatc cccggggacg tgcagaaacg ggccattgct tccatccgga
     7741 aggaactcga cgagagactg cccgagctcg gtatgctgga ggcccaccgc ctcgagcaga
     7801 ggacactgta tgacctggag atgatcgagg agaccggttc ctgcaagggg atcgagaact
     7861 actcgcgcca cttcgacttc cggaaaccgg gggagagacc gtactgcctg ctcgactatt
     7921 tccctcccga cttcctcatg ttcatcgacg agagccacca gactatcccc cagctgcacg
     7981 gtatgtacca tggtgaccgg tcgcgcaaga aggccctcgt ggattacggc ttccgcctcc
     8041 cgagcgcgta cgacaacagg cccctcatgt tccgggagtt cgagcagttc atgcggcagg
     8101 tgatcttcgt ctcggcgaca cccggcgact acgaactctc ctgctctcag caggtcgtcg
     8161 aacagattat ccgccccacg ggactcgtcg accccgaggt catcgttcgc gggactgccg
     8221 ggcaggtcga ggacgtgatc agggagatcc acgcaaccgt tggacgcggt gaccgcgtgc
     8281 tcctcacgac cctcaccaag agactcgccg aggaactcac ggactacctc gccgaaaaag
     8341 ggatcaggac gcggtacctc cactccgaga tcgataccct cgagcggacg gagatcatcc
     8401 gggaactccg gcttgggacg ttcgacgtcc tcgtcggtat caacctcctg cgggagggtc
     8461 tcgacatccc ggaggtgggg ttcatcggga tactggacgc cgacaaggag gggttcctcc
     8521 gggacgcacg cagcctcatc cagatcatcg ggagggctgc ccggaacgtc aactcgcggg
     8581 tcgtcctgta tgccgatacc atcacggggt cgatccaggc tgcggttgcc gaaacggaga
     8641 gacggcgtac tctccagaag gaatacaacg ccctgcatgg gatcgtcccg cagaccatcc
     8701 ggaaacctgt ccccaaaaag gaggtcgata tccgcgacac acggcatgtc ccgaaagccg
     8761 agatcccaaa cctcctcgtg gagctcgagg cacggatgtt ccaggctgca gagcgccttg
     8821 aattcgagga ggcaatccgg atccgtgata cgatcaggga attgaaggaa aaggtgggag
     8881 tttgaataat tcctaatttt taacggtccg ggctgatcca ttcaggagga tggttgagac
     8941 cttccccata agttcagcaa ggcaacctgt ctggcgaaaa agggagagtg aagtctcttt
     9001 tcaaatttta aaaaaaaaaa agtccttccc ttcaggggaa ggggagaacc tcgactacgc
     9061 tgtccttccg gacagactct gtgtttccat atgcatctga taccgtgagg atcacgtcat
     9121 aggatcccgg ttcattgaat gtataggtct ccgtcgcctg accggggtca aagactgtca
     9181 tgttgagtgc atcacgtacg atgacccacc tccatgaatt tggtgtcccg attgtctggt
     9241 cgatgagctt gactttgagg ggtgcggatc ccgtcgaggg ttcgaccttg aagtctgcaa
     9301 tgagtcttgg tttcacctcg atcgtctttg aggtagagct gctcgcaaac ccgtccgaga
     9361 ctgtcagagt tacggtgtag ttcccggcct ttgtgtaggt atggattggg ttcttctcgg
     9421 ttgtcaggtg gccgtcaccg aagttccagg cccacatggt cggagaatct cctgagccgt
     9481 ccatgaatgc aaccgtcagg ggagcgaggt tctccgggtt gcttgttgta tacgtgaacg
     9541 ctgccgtgag cctttcgcca acagtgatgt accccgtctt cgtcttttcg gcagtcccca
     9601 cgtcgtttgc agctgtgagg ctgacagtgt agacaccggg gacgttgtat tgatggaccg
     9661 ggttctgttc ggtcgagctg gtcccgtcac cgaagttcca gttccacgag gtcggaccgc
     9721 cactcgatcc atccgtgaac tttacgacca gcggtgccgg gcccgatgtc ctgttggcag
     9781 agaagtctgc aacggggaga gccctgaccg taatcagacc ttccttcgtg attgcgttgc
     9841 ttcccgcgga gtttctcacg ctgagtgtca ccgaatagac gccggggctg gtatacaggt
     9901 ggtacgggtt ctgctgcgtg gacatgctcc cgtcaccgaa ggtccagacc caccctgtcg
     9961 ggttacccat ggacgtgtcg gtgaactgga cgagcagggg ggcgttcccg gatgtcggtg
    10021 tggcagtaaa gtcagcaacc ggtgtcctca cgactgtgat gtaggatgtc ttggtaatgc
    10081 tccttccctc gggtgcaccg gtgttgaaaa ccgtgagcgt gacattgtac gttcccaccg
    10141 cattgtaggt atggacaggg ttccggtcga ggatcccgct ctggctcccg tcaccgaagt
    10201 cccatatcca tgccgtcggg ttgttcgtgg taagatcggt aaaccggacc gtcaggggca
    10261 ccgtcccgta gaccgggctt gccgagaaat cggggaccgg cggcgggggc agtatctgga
    10321 agccgtttgc gagttgcccc gacttcccat cgtcgttcgt gacaacaacg ttccagagac
    10381 cgatggttcg accctgcagg ttcaccgtgc agttcagggt cgtggcattg atgacgtgca
    10441 cgtctgttgc ctcgatcggt gccaggcccg tcctcgtgag tgtgacagtc gcaccctccc
    10501 tgaagtagtt acctttcacg gctgttatct gcagcgggcc gtcatttgaa cccttgttgg
    10561 gcagtatcga ggaaacgacc gggttcgggt actcgattgt gaacccgttc acatgcgttg
    10621 cggactgccc gtcgttgttc gtgaccacga ggtcccattc tccgacatcc atcccgttca
    10681 ggttgaatga cccactcaat gcactggagt tgatgaggct gacacccgtt gcaacgatat
    10741 cagtgtgaga tgcccgggca agcttcacgg tggcaccact cctgaagttg ctccctgtga
    10801 gggtgaacgg gacgatctgg ttattgttcc ccttggcagg ggttattcct gtcaccgttg
    10861 gtgcggggta ccggacctcg aaacctccgg agatctcccc ggcctgcccg tcatcgttcg
    10921 tgacgataac atcccacgaa ccgggcacgg cccccgccag gttgagcgtg caggtgatct
    10981 ttccggaatc gaccacagtt acgttcgttg caatgatatc ggggagcgac gcccgggtca
    11041 gccttaccgt tgcgtttgga tggaacccgg atccggacag gttcgagatc gtgatgggac
    11101 cgtcgttggg accggacgcg ggttcgattg ccaggactgc cggggctgca gggtaccgga
    11161 cgaagaaggc attctcgagg gttcctgact ggccatcgtc attcctgacg acaacgttcc
    11221 aatagccgac acgtgccccg ttcaggttga agaagcacat gatggtctgg gaggtaacat
    11281 tgatatccac tcctgttccg ggaatgtcat tttccccttc ccgtgtgagc ttcacggtgg
    11341 cattgggaag gaagccgctg cccgtcagtc cggtgattcc aaccggtccg ttgttcggcc
    11401 ctgaatcggg gacgatatcc tgcgggttgg gcggcgggtt cgtgatggtg aagacaacag
    11461 gctcgatact tgtccgcccg tcggggtttg cgacgacgac tgtccatgcc cctgcctttt
    11521 tccctgtcag gtcaaatgtg cacgagagtg cagttgcatt tatccacgtt accggactgc
    11581 cggtaatggg atactctccc gatcgtgtga ggtttacacc cgcgccgggc aggaaattct
    11641 cacctgtaac gacgacgttc tccagcaatc cggtgttctg tccctcatgg ggagatattg
    11701 catggacgac gggggccggg ttctggatgg tgaagacacc ttcccatgtt ccggacaggc
    11761 cgtcggtgtt cgtcactgtg acattatatt ctccggcctc cttcccggag aatgagaccg
    11821 tgcaccggag atgtgtgctg tttacgtacg tactgctttc cgaaaacgtc gttgatcccc
    11881 tcgtaaatgt gacggttgcc cctgaaagga accctgtccc ggtgatatcc agtagtacgt
    11941 aatctcccgt gttaagtgcc gaggacggat caacgtctgt taccgtaggc ggagggttgg
    12001 tgacggtaaa tgcctcaacc ttcgtggctc cctgtccatc ctcgttggtg acggtcaggt
    12061 tgtatttccc ggcaggaact ccggtgaggt tgaaccggac tccgatatca gtccccgata
    12121 ccgagaggac gctccctgca actgtctgtg tcccctttgc aaggagaact gccgggttct
    12181 cgtggaagcc gctgcccgtc acgtttgcga ggatgttgcc cgtgttctgc ccggtggccg
    12241 ggacgatgcc ggtcaccgaa ggggcatcag ggtaatagat cgtgaaaccg gatggcaggg
    12301 ttccgttctg gccatcaaga ttcctcacga cgacatccca ctttccgaca tgggcgccgt
    12361 ttaagtcaaa gaagcagagg atcttgcccg atgactcaac gattgcacca ttgatcgtgg
    12421 gaatatcatc atgtcctgat ctccggagtg agacattcgc ccctggcatg aaaccggaac
    12481 cggacaggtt cgttatccct acgaccatgt catttgtacc ggatgatggg taaatggccg
    12541 tgacaacagg tctcggatac cgtacctcga acccattgat cagggtcttg tactttccat
    12601 cttcgttggt caccgtgacg ttgtagaatc cgggttctgc gaacgtgatg ttgaagcggc
    12661 aggtgatctg cgatgaactg acgcgggtga cgttttcacc ggggatgatt gttgcacccc
    12721 tcgtcaggtt cacggtcacg tttggcagga agttgctccc ggcaaggttc gtgatatcga
    12781 cccagtcgtc gttctccccg aatgaggggg aaatggccgt gatttcagga cttggattct
    12841 cgatggtgaa tgccttctca agagtgacgg attcgccact ggtttcattg gtcacgacca
    12901 cgtcccagag tcccgcctta cggccggtca ggtcaaagac gcatgtaatc cgggaaggtg
    12961 aaaccacggt gacatacctg ccggtgatgt tctcctcacc gctcatcctc aacgcgactg
    13021 ttgcttctcc ctggccggga aagtccgttc ccgacaggtt cgagatgtac aggtcatcct
    13081 ctgtgttcag tccgctggat gggtctatcc cggtaatggc gagtgtggcc gacgccggga
    13141 tcaccagggc gagaaacacg aggatagtaa ctactatctg cagccctctt tcgcttgtca
    13201 tacgggtacc tcagatgcat ttttgtatac attccccaat tggaaatcgg cggtgacagg
    13261 tcactccaat tcccaaacaa atgtattcac catatcctct tcacatatct atttaaaact
    13321 ttccctcatc cgggttcata aaagccccct tttcacactt ccgtcccatg aaaaacgcag
    13381 aaacgggatc aggtaaaccc gtgaagagat gcacaagact tatcaccaat tcccgctcgt
    13441 tccttggaac agtacttttg ggatgcccga aaaaaaacca aaatagaaag ttattcagga
    13501 acttgttccc ttatcttccc ttttcatcga catggcaaat gaaaaggatc agcggtcaat
    13561 accccggtac tgtcccaaac agggaggcaa aaaggaaagg gaagaggcag aacgcgcgta
    13621 tatcacacaa gggatggtga ctgttgcttt accggctgcc tcaccgggat cagtatcaga
    13681 aaccgggttt tgtcctgagt gcctcgacga ggagcctgac cccgttctcg atgtcactta
    13741 tgtccactac ctcgacgggt gaatggatgt aacggctcgc aatggagagc gtcgtgcttg
    13801 gaatacctcc cctctccagg tgtatggcgg tcgcatccgt cgtgcccccg ctcccgacct
    13861 cgaactggac cggaatgctg cacgattctg cagtatctgc aagccacctg accatcgggc
    13921 ggctcgcaat gaggcccctc ccgctcgcat cggcgatggt gatgatcggt cccttcccca
    13981 tctcgacggg cacgtccttt tgatcgatgc ccgggtggtc acccgggatg gtgacatcgg
    14041 tcgcgatggc acaatcgggg ttgatggtgt acgcactggt ctttgcccct ttcaggccca
    14101 cctcttcctg cacggtgaag actgcgtaga gggtgtgggg ggacttcacc tgctgcatcg
    14161 tcttgatgag aagtgccact ccgaccctgt tgtcaaatgc cttgccggtt atccggccat
    14221 gtgcaagggt tgcaacctgg cggtcgatcg tgatgggtgt accaacggag atgccgagtt
    14281 ccaccgcctc ctcccggctg cgagccccca cgtcgatgaa catatcctca atcttcacgc
    14341 ccttctttcg ctcctcctcg tccatcttgt ggggaggttt gccccccaga acaccggtaa
    14401 cgcggccttt cgtcccgtgc aggatgaccc tctggttgta gagagtcggg gcgaaccacc
    14461 cgccgagggc aacgaaccgg atgaatccct tttcatcgat ggatttgacc atcagcccga
    14521 tctcgtccgc gtgcgccgcg agcatgaccc ggaatttccc cccttttttg actgcgatga
    14581 tgttgcccat cctgtcctcg gagatctcgt ccacgtaacg tctcaattcc ctcttcacga
    14641 ttgccgcgat gctgtcttcg ctccccgata ccccgtgggc attggaaagt tttgtcaaga
    14701 gttccatgac catatccact catccctcca tggctttcct gatcctctcc accgctgcct
    14761 ccagtgtgct gcggctcgtt gcgtaactca tccgggcata cccgggggca ttgcacccga
    14821 aggcgttgcc ggggacgata acaactcctg atttcaggat tttagcggtg aggtcttctc
    14881 cgaatggcac gaacatgtaa aaggcacctt cgggtcttgg aaatgaaaag cccatcctgg
    14941 tcagttctcc gtagaagtaa tcgcggcggg cccggtattc ctccctcatt gctgcaacgc
    15001 agtcctgcgg accattatat gcggctaatg ctgcatactg cgagatcgag gtcgcgcatg
    15061 cctggcagta ctggtggacc ttgagtgcct gctcgatgta ctccttcgga ccggcaagat
    15121 acccaagcct ccatcccgtc atggcataag tcttgctggc agcgtttacc gtgatgacgt
    15181 cttcgccaaa gagggctgca ctccagtgct tcggcccgta tatgaaatgc tcgtacacct
    15241 cgtcactcac gaccgtgaca ccgcggtcat ttgcgtattc gacgagggca cggatatttt
    15301 ccttgggttc cactgcgccg gtggggtttc ccggcgagtt gaggacgaaa agccgggcgc
    15361 cgtctatcgt ttccttggcc ttttcgacat cgatgtgcat gcgtgcatcg agggggacgc
    15421 cctgcggacg acctccggca aggattgcaa gtgccccgta tgagacaaaa cccgggtcag
    15481 cgtagaggac gcggtccccc tgcccgacga gcgcgtgcat gatgatgtgg agagcctcgc
    15541 ttgctcccgc cgtaacgatg atctggtccg gtgcatagga gaggtcgttt tcatttttga
    15601 acttgcgcga gagtgcctcc cggagctcgg ggatacccat gttcggggta taccctgtct
    15661 ttccctcccg gatcgccgct atcgcccctt ccttgatgtg accgggagtg tcaaaatccg
    15721 gctgcccgag ccccaggttg atcgagtccg gtcccgcaga ctcaaagagc ctgcgaatcc
    15781 ccgatatctc tattccgagg catctttccg cacaccgtgc tttcttcatg gatcttctcc
    15841 tcctcattca atgtttgcat gcctgttctt gagttctttt tcgtctgtct tcgtgatctc
    15901 catcaaccgg gagatgacgg catcggcaaa gaccatggcc gcagtctcaa agagcgtccc
    15961 caggggagca aacgacttgt gttcccccat gacctggcgg atctcgaact ccgccccctc
    16021 gtccctgacc tcgtcccggt ggtgctcgat gatcacgatt gtgtctgcaa tcctgccaat
    16081 ccgcgagtcc ctgtcggagg tgatgagggc gaccctgccc cctatctcct tggccgtttc
    16141 cgcgatgtcg gccaccgttt ttgtcttacc ggaacccgaa aagacgacaa cgaggtcgcc
    16201 cgggctcatc gcaggtgtaa tggtctcccc gacaacgtag ctcgaaaggc ccaggtgcat
    16261 caggcgcatt gcaaatgcct ttgcaacaag ccccgacctc cctgcgccca tgacgtagat
    16321 ccgccgggca tggaggatct cgtcgatgaa ctcttccacc tcctcatcgg agagcgaccc
    16381 ggcgatagct gtaatgcgcc gtgccatgag gcgcatcatc tcctggaccc tctgcgctgc
    16441 cattatttct ccggtaaaac ttctccttcc cctatgatag aagttgggat gaaagagcgg
    16501 gcacaggcat ctgccgggat ggggaccgga tctgcaagcg ggttatccga atctgtcgtt
    16561 ccgcatccgc gtgcgacctt cggccgttcg ctattctccc gggaccctcc ggacgggcga
    16621 agcgggaacg agccgtgtcc cttgcaggag agagacaggc ccgtgcccgc cgcagaccag
    16681 gcattccgac cgcccaccgg ggtaggatcc gttcgtctgg cggacgatgc caaagatctc
    16741 ctgcctctct tccctggcct tttcgctgtc aacgttgacg gatgtcacga ggttgaccgc
    16801 aagagtattg tactgcgccc tgtcgggggt caggtgatcg aagtttattg ccgtgtctgc
    16861 agaaaagaac accccgagat cgcgggaata gaggtagatt tgaccgaaga ggtgcccccc
    16921 gagtccttca aggacgagga accggtacct tcccgccctg acctccccta taacggggaa
    16981 cgcccctacc ctctcatccc ctgccggcgg gaagagaacg atgtcgcggg gaggagaaaa
    17041 acgggagaag atgttgataa gcgacgtgta gacctcctcg agtatcgatt catggttacg
    17101 ggacccgtat gccctgttgg aaacgaggat gatgtcacgg gtcccggcgt gcatcaggca
    17161 gggaacggta aagagacccc cggcaccgca gtggtccgca tccgcgtgcg tgatgataat
    17221 ccgcgagagc cggtcgagtg ccccggggac ttctctccgg atgatctgac agatatcagg
    17281 gtaatagata ccataacccg tatcgaccat cacgcattca ccgggcgaat cgaggagaaa
    17341 gaccgagccc ccgcatggtg gctggatgca gacgaggagg aggtcggggg caagacggat
    17401 attctggagg tccgcgtaaa aaccgggacc acacgtgctt ttcagggtcc gtcccgtctt
    17461 ttcaacactt tcgaaaacgg tttttgggtc cttgcccctt ttcatcagtt cctgggcgac
    17521 gtggttgata tccccaagga gagagaggag gaatgcatcc tcggattctc ccacgatgtc
    17581 gcggagggat tgggcaaaac ggagataaaa gacggtgtca tcgaggtatt tcccgctcgt
    17641 gtcgtaatcg aggacttcca tgcggtagcg ggacttgaga tcgtcgagga gctttgtaac
    17701 ttcctcctct tccccgaggt tgaggctgac ggtgagaatg tgcggcctgc tccccctgtc
    17761 gtcgaaatca atctgggcaa tattggcctt gtgggcggtc gtgaaccgga ggaagtcgct
    17821 gagagccccc ggtgtatggg gtatatggac tgacagcttg aggaaactct ggggcttgag
    17881 ggcagtctgg aggtacccga gttcccggag accccgggcg atctcttctc ttgcccccgg
    17941 cccggatgtc acttcgaaaa agaccgtgca gggatcgatc ctcctgtcga actggatcct
    18001 gttgatgttg cccccgttcc gcgaaatgac atcgacagca gggtgaagtg cgccgggcct
    18061 gtccgggacg cgggcgatga aagaatattt ctccgtatcc atcgggatgt caccccgtat
    18121 accagggaac ccttaataac gtcatgaccg ggcctgaccg gttttttgtc ccggttcccg
    18181 gtaacgcctc aatcgcgttc catctcctcg tgcccgagca tcagtgatcc gaatatgacc
    18241 ttttcgagga caacggatgc atacttgatt gcctgggcct tctccatatc ctcgttccgg
    18301 tggatgtctg catagacctg gagccggaca agggcgaacc tgaggcggtc gaggtgagca
    18361 tcatcgtagg aacttgcttt ccggtatatc tcctccacct tccatggaag gaggcagaca
    18421 tcctcgagaa cgggtacaat atcgtcgtaa atatcgagag gttcgcctcc cccggtgagt
    18481 acttcgcgaa agtccattta cccctcgacc accttcacga gctcttccat gaccttgtcg
    18541 acgctcttcc atgtcgggtt gtcgtggctc cggatgatga acggttttcc ttcgtcaccc
    18601 gccttcctca tctcgggatc gagggggatg ctccccagga acgggacacc cagctcccgg
    18661 gcgacagcct ccccaccccc cttgccaaag aggtcgatct cctgtttgca gtggggacag
    18721 acgagcccgc tcatgttctc cacgataccc acgaccggga cgccaagctg ttccacgaat
    18781 ttaatcgcct tcatggcatc catcgtggcg acttcctggg gagtcgtcac gatcacggct
    18841 cccctcacgt tcggagcaag ctggacgatg gagagcgcct cgtcacccgt acccggcgga
    18901 aggtcaacga cgaggaaatc aaggtggccc cagtccacct cggagaggaa ctggctgatg
    18961 gcgctcatct tcatcgggcc ccgccatatg actggtgtac ttttgtcggg gaggaggaat
    19021 gccatggaca cgaccgcaag gttccctgtt accctcacgg gctggatcat atttccgagg
    19081 gtggtcaggt gttgaccctc aaggccaagc atcttgggga cgttggggcc gtggatgtcg
    19141 agatcgagga gacccacgct gtacccatgg gcagagagtg caaacgagag gttgacagcc
    19201 acagtggact tccctacacc tccctttccg gagaggacga ggatcacgtg gtccacgtcg
    19261 atttccgcct tgggagggag acccttccct ttcgacgttt tcttgtcgct gtcacactgc
    19321 ttcgcactgg ggcacccttc acaaacccca ttgcattctt ccggtgtctt ttttgcctct
    19381 tctgtcatgg atatcctcgt tgtgggattc tggtagtgtt tattattgga ctgaaaagaa
    19441 gaaaaatata gatcattcga gcaatcccat caatctgacc gcgatatttc cgcattcagg
    19501 accccgttgc agagcctgtc ggcttcctgt atccagggat ggtcccttcc tgtactgacg
    19561 tactcgaccg acgaataccc ctgttcgcag agcctgaccc tcgcacagag ttcacgcagg
    19621 ccgggcttgt ttaccctgta ttctccccgt aactggcgga tgacgagctg gctgtccgaa
    19681 caaatacgga ccctgtgtgc tccatgcttc tttgctgctg caagagcgtt gatgacggca
    19741 tgatattcag cctcgttgtt ggtctttttc cccagaaaaa ctgctttttt ctcgagaaca
    19801 cggccatcgc tgtccagcag gacgaatcct gctgctgcag gcccggggtt cccgcgggag
    19861 gccccgtcag tatagcaggt gattactgct tccattgtcc ctttcccttt ccataactat
    19921 caagatgagc cggaacaata aacctcgcag gtacaatgga gaaactggac gtatcccttg
    19981 gtttcctgga gttcccaccg gttcacacgt gcgacggtga ggatctctcc cccctcatcc
    20041 ggattggaaa ccccagggga cagttccttg ccctcatggc aatcaacccc ttcatccctt
    20101 cctgttgctc gttttcgacc tggattgcat ggaacattcc cgtcacgggg ataattcctt
    20161 ccggtatccc ccgtgacccg gttgtatcgg accctgtgag tgcagtccag gggacaaacg
    20221 actggggcac catcgggtac cggggcccct gcccccgtcc cgggacgacc catcgggtca
    20281 cgttcaaggt ctgggctctc gacggacccg tccccgttcc tcccggcagc aggaaagcgg
    20341 acctcgttgc cggcatgaga ggacacgtcc tcgcctacgg ggataccatg gccctttatt
    20401 cgcggtagat ttcatttcgg ggggggcgac tctcttatat cccccgtgca ccaacgatcg
    20461 ggtatggaga agagggacat tgccatcctc atgctggcac ttgcaggcat ggtcatcctc
    20521 gcgggggtcg tcaagcccct cctgacgggg cagtccattg acttaagcct cccccctctt
    20581 ccgggcatcc tgccggcaga gccaacgccg gtacccactc ccgaaacgca cattccaagg
    20641 gtcacaacgg cacctccgac cagggagaca cccccaccca ctcccacctg gagcgggaag
    20701 ccccagaccc ttggatacgt tgccctggtc actccttcac cgaccccttc attctcgatc
    20761 cttcccgaca cgtcagcccc gccggagaaa ctgctcacgt atgcaacgat acagtcccat
    20821 gccggcggca tcacccaggc gatggcaatg ccgtttccct actgggaact ccactacacg
    20881 gtcgacccat gggagaccac attcgtgggg gagacctcat ccaagatggc cggtcaggct
    20941 gactatttcg cttcagagat attcccttct ttctcgatag aggtgaggga tgccgcagat
    21001 ggttcccttg tcaggaagat cgagcccccg ggaggcctga atgcaaaatt gtggaaagag
    21061 aacaaggaaa acgacccgcg tccctggatc gaaaaatttt acgagggaac cacgacccgg
    21121 tcatactact tcgttgtcaa cacgcacatg atccactcct ataaaatgga ggtaaaggtc
    21181 ccggaacgat acctgggtaa atactgatga aaagcacgga atcccggtaa caacctgtgc
    21241 cggactgtta ccacccgggt tagaaaaaag aaggatccag cttcttccta ttgattattc
    21301 aatgtcaagt ttccgttttc cgagggcctc gatgtactgg acttcctttc cgacctcgat
    21361 cttgtccatc ttgtccgggg gaacctcgat ctcgaaatta ttgaattcct tcatgtccat
    21421 cagggtcgcg atctgaccgc ttatggtgat gacctgcccg ctctttctct ccaccacggg
    21481 gacgtatgtc ttggcagaga ccggctggac gatggatctc ttcactccat cgaaaagacc
    21541 aacggcatcg atgcgggcct tggcagcacc gtgcttgccg ggtttggaga cggagattcc
    21601 cagtatcttg catggttcat cgtcaatgac catgtaacgg ccctccttca gcttccctat
    21661 ctctgtctgt tccttcattt gggttcactc tcgcgcaaaa atgcagtaag atgtatcttt
    21721 atatcaccag ataaatactc ctaaagaaac ggtcggatct ggcacaatgg aattcctgga
    21781 ggcatgtcat ctccttgccc gcgatatccg tggcgcaatc agcgggctcg ttggcacaga
    21841 aaagggggga aagaacctct gtatcggggc tgacgggaca ccgaccaagg agatcgaccg
    21901 cgttgcagag gattgcgtga ttgcgttcct ggaaaagcat cccctctgca ggaccctgat
    21961 ctccgaagaa gcaggcaggg tcagtcttgg aggcgaaaag ggaaccatct tcctcgaccc
    22021 gatcgacggg acatacaatg ctgtggcagg aatccccttc tatgccctct ccgttgcgta
    22081 tgccgaggat ggaattgttc tcaagggttt tgtccatgac cttgcggggg gagagacttt
    22141 caccgcaatc aggggacagg gggcatttct cgatggcagg cccatctcgg tgtcccggat
    22201 atcacggctc gatgaatgtg ccatgagcgt ctacgggaga aagttcgatc cccgcagggt
    22261 catgcatatc gggcagaaga tacggcgctg gcggttgctg ggggcctctg cactcgaact
    22321 ctcctacatc ggatgcggga ggatagatgg atttattgac ctgcgtggca cattgagggt
    22381 gacagacgct gcggcgggca tgctggtatg taccgaagcg ggagggatgg tcagtgatct
    22441 cgaggggcgg ccaatccggt tcccggacga ggtgacgatc ggcaggtgca tggtcgccac
    22501 gaacggcgtc cttcatcata aagtaatcga atacttgagg taatggaaat ccggtgtctg
    22561 aaatgaggat tgcacttgtt tcgcgggtgg atgaccagcg ggccatttct tttacaaggg
    22621 atctcggcga taccatcggg tcgctgggac acgaggtctc gttcgaacct gcaacggctc
    22681 gcgtcctccg ttcagacaat ctctggccat tcgacgggag cgtcgacctt gccatcatcg
    22741 tcggtggtga cgggaccatc ctgcacacga tccagcagat ggaccacaag gttcctgtca
    22801 tcggcgtgaa ctggggggag gtggggttcc ttgcggacct cgaacccgac gaggcgatcc
    22861 ccttcatccg gggcttaaag cccgggtttc caacagagcc acggatgagg gtggcactga
    22921 aatccgggga aaccgtcctt ggagaggctc tcaacgaggc tctcatcgtg acgagccgcc
    22981 ctgcaaagat gctcaggttc gtcatcgtcg tggatgggat cgaggccgag agcttccggg
    23041 ctgacggtct cctggtcagc acaccgacgg ggtccacggc ttacgcgatg agtgccggcg
    23101 gcccgatcgt cgacccgcgg atagaagggt ttctccttgt cccccttgca ccctacatgc
    23161 tctcttcccg cccccacctg atcagcaacg atcggagcgt caggatcagc ctcgagagtg
    23221 caaaacccgc cacactcgtc atcgacggac aaaagaccat cgagcttgga aacgaacaat
    23281 tgctggaggt aacacaggca gaacagcccg ctctcttcgt ggacgctcac aagaactttt
    23341 ttaaaaaagt ggatcacaag ttgaggcacc tctaaggtct tttcttactc ataagagcag
    23401 atttatctct tatcagcccc agcactcctc acgaagagag atggaagtga gaaggatgga
    23461 tgcaacgatt atgaaagaga tggattaccg ggaggcctct gcagtccttg tcaaatcact
    23521 cgggctgaaa aactcccctg ttgcgatcag gcttgccatg ggaaaggagg aaattcccga
    23581 gggtatggaa aaacttgacg gaacaatacg gcattgccag atggtgaacc ttgcccggaa
    23641 ggaggggcgt gtcttctatg caacagtcga gaaccacgag tgcatgggcg gggcatgggc
    23701 actcggtctc cggcagatca ccgagaccct gaaaaacgga cagttctact tcaaacttgg
    23761 gaaattcgag agcactgccg cctgcaagag gacgatcgac cggatacccc acgtggagtc
    23821 cgggtcgacc tatgcgacac tgtacgcacc gctcgaaaaa acgaactttt cgccccatct
    23881 catcctcgtc atagccgagg cacgggcaat gctcaagctt gcacaggcca cgctcttccg
    23941 gctcggcgga aggattacgt ccgagttctc aggaatccag tccgtgtgcg cggatgcatg
    24001 tgcccagacg tttctctcgg ggaaggcaaa ttactccctc gggtgcgacg ggtcgaggaa
    24061 gttttccgga atcgaagacg gggagatggt gatgggattt cctgtcgaga tgctcccgga
    24121 gatcgtcgat gcagtccgga tcgtgaccgc cgcacccggg tcaaagaaat gagagccgga
    24181 atgggagaga aaatactcct cttaccccct ttttcccgga acaggcaatg gaattgacat
    24241 catggtcaat tccggaaaaa aatgagtaga taagtcatgc tattccccca tgcagtcaca
    24301 ttcccggctt tttttccgtc atgcagcacg cgca
//
LOCUS       DAOOJU010000025        21668 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2446_length_21668_cov_16.239948, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000025 DAOOJU010000000
VERSION     DAOOJU010000025.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 21668)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 21668)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21668
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2446_length_21668_cov_16.239948"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(320..976)
                     /locus_tag="PK679_06940"
     CDS             complement(320..976)
                     /locus_tag="PK679_06940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HPC55727.1"
                     /translation="MKITWLGHSCTLLSGSRTVLIDPFVPEGKIRAKPDIVAVTHGHA
                     DHMGCVSDFPGVPVVAVNEVAKYLQSRGMEAEAMNIGGTIEVKGVRFTMTPAVHSAWL
                     EEAGPGHTGGAAAGFVVRMDGKAVYHAGDTALFSDMELIGKLYHPDVALLPIGSRYTM
                     GPEEAMVAARMIGAPVVIPIHYNTWPIIAQDPSGFARALERTTDCRACILEPGQSITL
                     "
     gene            complement(1062..1670)
                     /locus_tag="PK679_06945"
     CDS             complement(1062..1670)
                     /locus_tag="PK679_06945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator receiver protein"
                     /protein_id="HPC55728.1"
                     /translation="MQEDKRKRELLQLFSNISGKTKIVEPMKKIHGTLRDRDAVEREI
                     ALVMREILEQGFFKTKLKPIQLARLISSYYAGKNDTEIARELGDEKLSKTVARARVRL
                     KLFRDLDFKMPFDQDRMEELLSSGKTMKEISEELGVSPSTLREYRHVIEQRDDTTIDP
                     FLERIRDVMEDRDLSEQMTRSATKDSLGESIDITEAELIDVT"
     gene            1885..3609
                     /gene="glyS"
                     /locus_tag="PK679_06950"
     CDS             1885..3609
                     /gene="glyS"
                     /locus_tag="PK679_06950"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="HPC55729.1"
                     /translation="MSDIYDTIMDLAKRRGFIWPTAECYGSVAGFIDYGPLGSMMKRR
                     IEDVWREFYVVREGYYEIECPTIGQEEIFIASGHVKGFSDKMCQCPHCREYLRADHVV
                     EGAGIAGASAMDAAELARRLRDIPCPSCSEPLGEVEVFSFNLMFETSIGPGSQRKGYL
                     RPETAQGMFTDFSRLLRFYRDRLPFGAVQIGKSYRNEISPRQGMIRLREFTQAEAEIF
                     VHPEKKDHPRFSRYSGYRMPLLGIRQQQEGSPAVEMTMQEAVDAGVVAHSFIAYYLAL
                     THDLLVTIGVKPERLRFRQHLPDERAHYAMDCWDAEVYSERFGWVETVGIADRTDYDL
                     RAHEKQSGERFSVFIPYPAPRREKRVRVVPRMGALGPRFRDRAKMVAEALEASAPAEG
                     GISVSVGGEEIFIPPDLYEIREEEVEVPGEEVTPHVIEPSYGIDRMIYAVLEHSYAEE
                     VVKDEERRVLRLPPRIAPIQAAVFPLMNRDGLPEIAGRILEDLTSFGIVAEFDDSGAI
                     GRRYRRQDEIGTPFAITVDYQTPEDGTVTLRDRDSMEQVRVPVRDLPALIGSLIRGRT
                     TFAELKSP"
     gene            3606..5846
                     /locus_tag="PK679_06955"
     CDS             3606..5846
                     /locus_tag="PK679_06955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HPC55730.1"
                     /translation="MTAISHPYIAPGTLDSRAYQLSIAMKALEENTMVVLPTGLGKTA
                     IALLVAASRLYNQGGRVLMLAPTKPLVEQHLRFFSQFLSLPGQNERTFAMFTGETPAS
                     DRAGAWKDARVIFATPQVIKNDILSGSYDLADVVLVIFDECHRGVGNYAYVFIARRYL
                     ETARAPLVLAMTASPGGEREKVEEVCRNLGITRVESRTESDPDVAPYIHEREIEIIQV
                     DLPDELKKATADINALIDSRLAQLRSLGFMVPPRQQLSMKALNAINAQVQQKIQERDS
                     AGYMGASLYAELMKLRHAVGLAESQGSRVFCQYINRLLAEGTGSGSPKSAARLAKDPV
                     FIRVLERCMSWRGELHPKPGILADVVAEQLETSPESRIIIFATFRDMVQQIVDFLSER
                     GIPCQRFVGQATRDTEKGLSQKKQIEALQKFRAGDFRVLVATSVGEEGLDIPSTDLVV
                     FYEAVPSEIRSIQRKGRTGRSGRGRIVVLVTKGTTDEVFRYVSQTREKSMIAGIRRMH
                     HGTAPFESVPRSPPAVQSSIGDFPEKGPVVKVDDRETSSRVVEVLSTLRVQLAIGRLP
                     SGDYAIGDRILVERKTVRDFVDTLVDRDLFAQLKVLAESAPRPVLIIEGTDDIYKARD
                     IHPNAIRGTLAAIAVDLGISVLFSRNEEETAQIIGILARREEGGNRERTLPVRKTGYS
                     LREQAEMIIASFPDIGPKHARALLEHFGSVQAVVNAQEEDLVRVKGIGKERAKKIWEV
                     SHRPYR"
     gene            complement(5837..6235)
                     /locus_tag="PK679_06960"
     CDS             complement(5837..6235)
                     /locus_tag="PK679_06960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoantigen p27 domain-containing protein"
                     /protein_id="HPC55731.1"
                     /translation="MAGEGQTKREDEIMARYLLKGGKMLSATCPACGCPLFEIRGEKL
                     CVVCTERNAEKGEPAAGLTRPPHPGGVGGGEGTIPDGFRMKESLERAIVSLCEKAAAE
                     EDPVRAKILMEAVQAGADAFRKLAGKPDQR"
     gene            6350..6613
                     /locus_tag="PK679_06965"
     CDS             6350..6613
                     /locus_tag="PK679_06965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0147 family protein"
                     /protein_id="HPC55732.1"
                     /translation="MTNPEKTIENCIQMLQHIMDDSTIPRNIRRVADETRQLLMNNSK
                     KTGLRAAEAISKIDEISNDPNMPVHARTRIWELVSQLETIPLD"
     gene            complement(6797..7210)
                     /locus_tag="PK679_06970"
     CDS             complement(6797..7210)
                     /locus_tag="PK679_06970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HPC55733.1"
                     /translation="MYQTRIHQKTRGEGDIVDLSQRVREAVRESGVREGLVNVFVTGS
                     TAAVTTIEYESGVLKDLVRALSAIAPATIPYAHDGAWGDGNGRSHVRAAIVGPSLSIP
                     VTGGEPELGTWQQVVLLELDVRQERDRTVIITVMP"
     gene            complement(7299..9755)
                     /gene="gyrA"
                     /locus_tag="PK679_06975"
     CDS             complement(7299..9755)
                     /gene="gyrA"
                     /locus_tag="PK679_06975"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HPC55734.1"
                     /translation="MTSEQAGTAGAGQEPASQVIPVNIEEEMKTSYINYAMSVIIGRA
                     IPDVRDGLKPVHRRSLFSMWEMGNTHDKPTRKSARVVGDVMGKYHPHGDAAIYDTIVK
                     MAQPFTYRYPLIEGQGNFGSIDGDAPAAMRYTEVRLDPLAEELLHDIEKETVAFVPNF
                     DESLNEPVVLPAKVPNLLLNGSSGIAVGMATNMPPHNLREVCNALVQYLDTPDAPLEV
                     FMQHLPGPDFPTGGVIMGTEGIKSAYLTGQGKVIIRGVAEIEDRGSRGERIVITEIPF
                     QVNKARLIETIANLVKEKKIEGISDIRDESDKEGLRVVIDLKKGASGAIILNQLYKHT
                     ALESTFGIINLAIVENQPRILSLTGLFREFVAHRIEVIRRRSEYDRRKAQERAHILEG
                     LLLALSRIDEVIAAIRASETADVAKETLITRFGLDEPQAAAILQMQLRRLAALEQKKI
                     QDEKDELLKEIARLTEILADEKNIRREIRKELVAIAEKYGDDRRTRISAEATQLDRED
                     LIEDKQVLVSLTSLNYIKRMDLDTYRQQRRGGRGIIGMSTKEEDYVTDVFVANTHDYL
                     LCFTTTGRAYWLKVYDIPEGSRTSRGKAIVNLLNLDNEKVTAVIPVREFSRDRFLFFA
                     TRKGMVLKVPLEEFSRPRSTGIIAMNLREGDELVDVKITDGKREVILTTRKGQSLRFS
                     ESSVTEHHRGAMGVIGIRMRGNDDLRAVSLVEKDHLLTVTENGYGKRTDFAEFHGHGR
                     GTMGVRNILTEFRGGVVDAKAVSENDEIILMSASGIVIRTKVSEISIQKRSTRGVRIM
                     KMEEGDRVVGFAILRPEMEE"
     gene            complement(9745..11742)
                     /locus_tag="PK679_06980"
     CDS             complement(9745..11742)
                     /locus_tag="PK679_06980"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase subunit B"
                     /protein_id="HPC55735.1"
                     /translation="MADTYDASHITVLEGLQPVRERPAMYIGSTDTRGLHHLVYEVVD
                     NSIDEALAGFCTSIWVTIHGDGSISVLDNGRGIPVDEMNNTKKSALEVVLTVLHAGGK
                     FDKSTYQVSGGLHGVGVSVVNALSRWLHARVYRDGNIYEMRFERGRVTSPLASREESI
                     EELIARYQEWYGSRPAFRGSDRAEFLQKFGNRLSGTLITFAPDETIFETVRFDYDILA
                     HRLRELAFLNAGISISLLDERTGDSEKFHYEGGIAEYVRFLNAGAEPLHPDVISLKKN
                     DPESMTEIEVALQYTTGYSEQIFSYVNSVNTREGGTHLEGFRSAITKAVNNSARKNNL
                     IRETGLSIRGEDVREGLTAIISVKIANPQFEGQTKMRLGNSNVKGIVDSLVYQSLSDY
                     FEENPRVLSAIVEKVLTAARAREAARNARELARRKSTLETTGLPGKLADCSERDPARS
                     EIYIVEGDSAGGSAKQGRDRRFQAILPLRGKILNVEKATQHRILKNAEIQALISAIGT
                     GVGEQFDPEKARYHRVILMTDADVDGAHIRTLLLTFFFRYMKRLIEEGFVYIAQPPLF
                     RVAKGKVEKYAFREEEMKEIVKELGEKGVTVQRYKGLGEMNAGQLWSTTMDPASRVLK
                     RVTIEDASFANEIFEKLMGEDVAARRDFIKRHAREVTNLDI"
     gene            complement(11846..12154)
                     /locus_tag="PK679_06985"
     CDS             complement(11846..12154)
                     /locus_tag="PK679_06985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55736.1"
                     /translation="MASAFGRGFITNLMHICKHFSGKPEEAFFGAADHLEEFIVPDQF
                     RGTEIEELADRLRKRIVWHQPGTLDREEAEEVKKLINRLIIAIDKGLGIKDPDLGEFQ
                     "
     gene            complement(12194..13021)
                     /gene="cbiQ"
                     /locus_tag="PK679_06990"
     CDS             complement(12194..13021)
                     /gene="cbiQ"
                     /locus_tag="PK679_06990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HPC55737.1"
                     /translation="MIEELFFIEKQAYRKSPVHDIDARAKIILCFAAIVAMVAVPYSP
                     VVFPVGLVFFLLFAILWALSRLSPLVYGKRVLMVVPFGFFLIFVQIFVQNPYYTVYTS
                     IADLPFGIHVYRESVEFASVLFVKFLVSISFIILLSSTTRVQDLLEGAGRLGLPAEFS
                     LVLGMMVRYIFVFGYITRKVGESLAARCFSPFDRNLPYRYRLRVLAYTIGTLFIRSYE
                     QGERTYMAMLCRGYGRESHLYIRKKPLARRDLFFLLACMPVVVCTPVIAWLSSQGLL"
     gene            complement(13018..13851)
                     /locus_tag="PK679_06995"
     CDS             complement(13018..13851)
                     /locus_tag="PK679_06995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC55738.1"
                     /translation="MHLIETRDLCHVYPGNVRGLDRVNFIAPRNARIAVIGANGAGKS
                     TLFKHFNGILQPTSGTILIRGEPITRENVKEVRKFVGVVFQNPDDQIFSPTVEQDVAF
                     GPMNLGLDGETVRHRVEEALRVVGITHLRDRVPHHLSGGEKKRVAIAGIIAMEPQVLV
                     LDEPTAGLDPAGVRDLVDFVNSLARRFGMTVIYSTHDVSLVPEMADIVYVMDKGRIVA
                     SGTCREVFVQHEMLASVRLEVPVIPRLIGALRQEGVGISMAYTFDEAKNAFLEAFGRR
                     G"
     gene            complement(13906..14253)
                     /locus_tag="PK679_07000"
     CDS             complement(13906..14253)
                     /locus_tag="PK679_07000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDGLE domain-containing protein"
                     /protein_id="HPC55739.1"
                     /translation="MKKDNILIFGIIIALVIAVAAPFIASSNPDGLESAFFGIFGAKE
                     IHGSELNEDAAVAAEEQVQEITGNTFSYAAPFPDYSIEGLAKMGEALAIVAGTILVLL
                     VAFGLGKAFSRPG"
     gene            complement(14253..14891)
                     /gene="cbiM"
                     /locus_tag="PK679_07005"
     CDS             complement(14253..14891)
                     /gene="cbiM"
                     /locus_tag="PK679_07005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt transporter CbiM"
                     /protein_id="HPC55740.1"
                     /translation="MHIPDSFIPLLQAAVYWVIALVFIALSLRWARAEMREEKVPLVA
                     VLAAGIFAIQAVNVPIPWGTSGHMVGAALAAIVLGSPFAAVFVLTLVLIVQGVLFGDG
                     GITVMGANIINMGVIGGFVGFYSYKGLNRAIRNPYPAAFVAAWLSLFVSALACAVEMA
                     IAGTFPLGLGLFSMGLYHAVIGVIEGAITTVALYLIFTARPDILPKESGVTA"
     gene            complement(14940..16118)
                     /locus_tag="PK679_07010"
     CDS             complement(14940..16118)
                     /locus_tag="PK679_07010"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC55741.1"
                     /translation="MTGHFDVVVVGGGPSGSTCARLCAEQGLSVCLLEEHASAGIPVQ
                     CAGLLSLAAFEECSVPDSCIIATVRGARIVSSLGPVLSFDAGVPKAHVVDRAILDREM
                     LARAARAGAEIRMKTAFFRREGHSIVTRGIRGKEEISFGVLVGADGAASRVARESGMP
                     RPAHVLAGLQADIAWRMDEGLVEIHPDASPDFFGWAIPIGPGRARVGLAGLRDVRTTF
                     PRFLGRFFGDGHQASVHLVSGAIPIGPRARTYGNRVLLVGDAAGMAKPTSGGGVYTGV
                     RAARHAAHVIGEAVRKGKFSDDDLSPYEKAWRADFGRELSLGLRLFEVRRKMTPGDIA
                     GIIRALDDPAIIRDIVSLGDMDRPGKIVRRLATRPELFPLVGTLISSMVLKNFNKNIF
                     "
     gene            16294..16656
                     /gene="pth2"
                     /locus_tag="PK679_07015"
     CDS             16294..16656
                     /gene="pth2"
                     /locus_tag="PK679_07015"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase Pth2"
                     /protein_id="HPC55742.1"
                     /translation="MEREPQFVWKQCIVVRSDIRMSCGKTCAQVAHAAIIAYERADAA
                     TRKKWFQEGQKKVVLKVPGERDLLELKSLAEHSGIATGLVQDAGLTEIPPGTVTALGL
                     GPAKSEDLDRITSSLSLL"
     gene            16715..17986
                     /gene="truD"
                     /locus_tag="PK679_07020"
     CDS             16715..17986
                     /gene="truD"
                     /locus_tag="PK679_07020"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0031119 - tRNA pseudouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HPC55743.1"
                     /translation="MKESPYPLEKFLGMRYYASDTPGTGGRLRERAEDFAVDEVFAAP
                     GDEGPYLVCRLTKRNWEMQRAAREIARQLGISHRRVSWTGTKDTHALTTQLIAIYGVR
                     ENDIARVTLGDIEIVPVGRSQQPLSLGGHEGNRFSITIRDTRSSDPGRELAEVAETCR
                     QGIPNYFGIQRFGVARPVTHLVGLHILKGDLEGAVTCYIGRACPGEDPAVREARGEFL
                     SSRDPAAALRSFPVTLSYERAMLHHLVSHPGDYRGALCSLPPRLLSLFVSAFQSHLFN
                     CTVSSRMERLGDDFRIPHAGDRLLFPDGKEDVVSSPMLQAARTMASRGRCRVAIMVPG
                     SRPVQPAGEDDSAMALLLARHGISPEDFARASEIVGTRYNGALRPAVLSTDVAWTVAG
                     KDVTLTFSLGPGSYATTVCREFMKADPASMV"
     gene            complement(17997..18782)
                     /locus_tag="PK679_07025"
     CDS             complement(17997..18782)
                     /locus_tag="PK679_07025"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HPC55744.1"
                     /translation="MEEIPGHSQKPVRRLFVFALLLLLAFLAGAAAFWLLQWSDTQEM
                     GISVIRIEGTIVTGTGHGGGYTGSEYAGRAIRDAADDPLVKAIVLRVNSPGGTPAAAQ
                     EIIRDIRYAMEKKPVVVSMGDIATSAAYAISAPADRIYANPDTITGGIGTSWTFIDIS
                     DWLAENNISVEVITSGSRKDMGYGYRPLSPEEREYAGMIVNESNEGILSGILAARPVN
                     RSIIEDARVFRGQDALEAGLVDELGNLNDAIEGARKLAAGWKP"
     gene            complement(18760..19479)
                     /locus_tag="PK679_07030"
     CDS             complement(18760..19479)
                     /locus_tag="PK679_07030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HPC55745.1"
                     /translation="MPENRRRPHVLMMSEITVDGKLTLKRGASSKILMKYMDHATEIL
                     LHKTRAACDAIMVGSRTIQIDNSFLTVRLVPGKSPLRVIPSSMADIPPDANVLGPDAP
                     TVIAVCSRAPEEKVAMLRARGVSVVVAGEDHVDLPLLMEKLHDEFGVRRMMLEGGPTL
                     NWHMLHHRLVDEIRLIHLPFIVGGADTPSLVGGMHIEDESQMIRLALSSHYMCGTNLV
                     TEWRVLYSGKGGDTSGGDSGT"
     gene            19653..20285
                     /locus_tag="PK679_07035"
     CDS             19653..20285
                     /locus_tag="PK679_07035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HPC55746.1"
                     /translation="MNITALRPRFMRYIEPVAALFSRAGFSANQVSFLALVFGILCAI
                     LFSLRMFPAGSLALFVSVLLDLVDGSVARQTSTQSRFGAVFDWIVDKYVDALVIVGIG
                     VSGVPLVTRFLSLPPTADFCVVALAVTGSLMNTFIKPVVYAEIGYQERVDGKIEDPLE
                     GVGFFGRPETCLVLLIGGATGFIWISVIIIAICTNLSAVQRITYLYRTLA"
     gene            complement(20257..21063)
                     /gene="artA"
                     /locus_tag="PK679_07040"
     CDS             complement(20257..21063)
                     /gene="artA"
                     /locus_tag="PK679_07040"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaeosortase A"
                     /protein_id="HPC55747.1"
                     /translation="MKELLVLFSCIFFLAFLVPWRYRNHCAVLGWTGMVLFLFAEIPY
                     YLSINNVLYPVLAVLSVPFLAITGKNLLSGERLVRQLSTAAAVAFLIYAPFEFTPLGD
                     WLIAVVVDQTAAVLSLVGYPVDRLAWNLVSRNGYRVEIILACTGIQAIAIMLGVVSAV
                     RTTFRQKVLSFLLIVPVIYLLNIARNVGVIIAYSGQWFPYLPEIAGNGEPGYESFFWA
                     HNVIAEGLALLLLIGIAWGLFSIIPDLARYATDLVDLYIREIRRAFGRGT"
     gene            21232..21543
                     /locus_tag="PK679_07045"
     CDS             21232..21543
                     /locus_tag="PK679_07045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor S"
                     /protein_id="HPC55748.1"
                     /translation="MFCPECGSLMISSAGQLKCRKCGYNRKIDKNDQMQITRTRREKE
                     IVIVEEEGSVRTLPTIAVKCPKCEHNLAFWWLRQLRAADESEVRFFRCCECGHTWREY
                     D"
BASE COUNT         4265 a         6620 c         6441 g         4342 t
ORIGIN      
        1 tcgttatgga acgtgtcacg gtcaggttat aacattccat cccgtaatcc cgcaaaaagc
       61 ccccgttccc gccagccgta ccctggtccc ggtcacctga ggaaaacgta ccagagacca
      121 accacgatga tgaagaggat gacgcccgcc cctatcactg tcttgccgtc aagctccatt
      181 gcttatcaca cccggacaat ccatcaatca gtatattctt atataagggt atcggatgcg
      241 tcagcgcctg caggataacc atatgccgtt tccggtaatg agaaaaaggg gaaggcgatt
      301 atagtaagtg tttttccggt cagagcgtga tgctctggcc gggttccagg atacatgccc
      361 tgcagtcggt cgttcgttcg agcgcccgtg caaacccgga cggatcctgt gcgatgatgg
      421 gccacgtgtt atagtggatg gggatcacca ccggtgcccc gatcatccgg gcggcaacca
      481 ttgcctcctc cgggcccatg gtgtacctgc tcccgatggg gaggagggcg acatcggggt
      541 ggtagagttt tcctatcagt tccatgtcgg agaagagtgc cgtgtcgccc gcgtggtaga
      601 ccgcctttcc atccatcctg acgacgaagc cggcagcggc accccccgtg tggcccgggc
      661 ctgcctcttc gagccaggcc gagtggacgg ccggcgtcat ggtaaaccgg acccccttta
      721 cctcgatcgt gccgccgatg ttcatcgcct ctgcttccat cccgcgggat tgcaggtact
      781 tcgcgacctc gttgaccgcg accaccggga ctcccggaaa gtcagagacg caccccatgt
      841 ggtcggcatg cccgtgggtc acggcaacga tgtcaggttt tgcccggatc tttccttcgg
      901 gcacgaacgg gtcaatgaga accgtcctgc tccccgagag cagggtgcat gagtgaccaa
      961 gccacgtgat cttcattctc ggatccctcc gctcatgtaa gaaaatgatc gcttgggaag
     1021 agggcgctgg aagaaaaata gcttgtggtc ccggacaccg gtcaggtgac gtcgatcagc
     1081 tcggcctcgg tgatgtcgat cgactcgccg aggctgtcct tcgtggcact ccgggtcatc
     1141 tgctcggaga ggtcacggtc ttccatcacg tccctgatcc tctcgaggaa cgggtcgatc
     1201 gtggtgtcgt ccctctgctc gatgacgtgg cggtactcgc ggagggtgga agggctgacc
     1261 ccgagctcct ccgagatctc cttcatcgtc ttgcccgagg agaggagttc ttccatgcgg
     1321 tcctggtcaa acggcatctt gaaatcaagg tcgcggaaga gcttgagccg gacgcgtgcc
     1381 cgtgcaacgg tctttgagag tttctcgtcg cccagttccc gggctatctc cgtatcgttc
     1441 ttgccggcat agtacgacga gatgagccgg gcaagctgga tgggcttgag cttggtcttg
     1501 aaaaagccct gttccaggat ctccctcatg acgagtgcga tctctctctc cacggcatcg
     1561 cggtcccgca gggtgccgtg aatcttcttc atgggctcca cgatcttggt cttgcctgat
     1621 atgttagaga acaactggag gagttctcgc tttctcttgt cttcctgcat gaagcctcac
     1681 tggcagatta ccgaataaga tacccagcaa catatttaat gctatctttt cgcccggtaa
     1741 tagccggaat ccttccggaa agggccatga tctgatggaa tggtcctcct catacaaata
     1801 ttttatgcct tttcgcaacg ccggaaatcc cgcacagttt tttgtggcag cagtgccaga
     1861 tataaggaga gtgaccctgt gcccatgagc gatatttacg atacgataat ggaccttgca
     1921 aagcggaggg ggttcatctg gccgacggcc gaatgttacg gctcggtcgc cggtttcatc
     1981 gactacggtc cgctcggctc gatgatgaaa aggcggatcg aagacgtctg gcgcgagttc
     2041 tacgtcgtgc gggaaggata ctacgagatc gagtgcccca ccatcggcca ggaggagata
     2101 ttcattgcct cgggccacgt caagggtttt tccgacaaga tgtgccagtg cccccactgc
     2161 agggagtacc tgcgggcgga ccacgtcgtc gagggggcag gaattgccgg ggcatcggca
     2221 atggatgccg cggaacttgc acgccggctc cgcgacatcc cctgcccttc ctgcagcgag
     2281 cccctcgggg aggtcgaggt cttttcgttc aacctgatgt ttgagacctc cataggcccc
     2341 ggctcccaga ggaaagggta cctccggccg gagaccgccc agggtatgtt caccgacttc
     2401 tcgcgtctcc tccggttcta ccgggacagg ctgcccttcg gtgcagtcca gatcggcaag
     2461 tcctaccgga acgagatatc gccccggcag ggcatgatcc ggctccggga gttcacccag
     2521 gccgaggccg agatattcgt gcacccggaa aagaaggatc atccccgctt ctcccggtac
     2581 agtggatacc gcatgcccct ccttgggatc aggcagcagc aggaggggtc tcctgccgtc
     2641 gagatgacga tgcaggaggc agtggacgcg ggcgtcgtgg cccacagctt catcgcgtat
     2701 taccttgcac tcacccacga cctcctggta accatcggtg tgaaaccaga aaggctccgc
     2761 ttccggcagc acctccccga cgagagggcc cattacgcga tggactgctg ggacgcggaa
     2821 gtctattccg agaggttcgg gtgggtcgag acggtcggga ttgccgaccg gaccgactat
     2881 gacctccggg cacacgaaaa acagagcggc gagcgtttct ctgtcttcat cccctacccg
     2941 gctccccgca gggagaagcg ggtcagggtc gtgccccgca tgggagcact cggtccccgc
     3001 ttccgcgaca gggcaaagat ggtggcagaa gccctcgaag cgtccgcacc cgcggaaggc
     3061 gggatttccg tctccgtggg gggcgaagag atcttcatcc cgcccgacct ctacgagatc
     3121 cgcgaggagg aggtcgaggt tccgggtgag gaagtgaccc cccacgtcat cgagcccagt
     3181 tacggcatcg accggatgat ctacgcggtt ctcgaacaca gttatgcaga agaggtcgtc
     3241 aaagacgagg aacgccgtgt ccttcgcctc ccaccccgga ttgcacccat ccaggccgcc
     3301 gtatttcccc tgatgaaccg cgacggcctg cccgagatcg cgggccggat ccttgaagac
     3361 ctcacgtcct ttggcatcgt tgccgagttc gacgactcgg gcgccatcgg gaggaggtac
     3421 aggaggcagg acgagatcgg gacacccttt gccatcaccg tggactacca gacgcccgaa
     3481 gacgggaccg tgacgctccg cgacagggac agcatggagc aggtcagggt ccccgtcagg
     3541 gacctccccg ccctcatcgg ttcactcatc cggggcagga ccacatttgc ggaactcaag
     3601 tccccatgac cgcgatctcc cacccttaca tcgcgccggg aaccctggat tcgagggcct
     3661 accagctctc catcgcgatg aaggcgctcg aggagaacac gatggtcgtc ctcccgacgg
     3721 ggcttgggaa gaccgcaata gccctcctcg tcgcagcatc ccgcctctac aaccaggggg
     3781 gcagggtgct gatgctcgcc cccacaaagc cgctcgtcga gcagcacctc cggttctttt
     3841 cgcagtttct ctccctcccc gggcagaatg aacgcacgtt tgccatgttc acgggcgaga
     3901 cccccgcgtc agatcgtgca ggggcatgga aggacgcccg ggtcatcttt gcaacgccgc
     3961 aggtcatcaa gaacgatatc ctctccggga gttacgacct cgccgatgtc gtgctcgtca
     4021 tcttcgacga gtgccacagg ggggtcggca actatgcata cgtcttcatt gcccggagat
     4081 acctcgagac cgcccgggca cccctcgtgc tcgcgatgac ggcgtcgccg ggcggcgaga
     4141 gggagaaggt agaggaggtc tgcaggaacc tgggtatcac ccgcgtcgag agccggaccg
     4201 agagcgaccc tgacgtcgca ccctacatcc acgaaaggga gatcgagatc atccaggtgg
     4261 atcttcccga cgagctgaaa aaagccacgg cggacatcaa cgccctgatc gactcccggc
     4321 tggctcagct ccggtccctc gggttcatgg tccctccacg ccagcagctc tccatgaagg
     4381 ccctcaatgc catcaacgcc caggtccagc agaaaatcca ggaaagggac tctgcaggct
     4441 acatgggagc gtccctgtat gccgagctga tgaagctccg ccatgctgtc ggcctcgcag
     4501 aatcgcaggg aagccgcgtc ttctgccagt acatcaaccg cctgctcgcc gaggggaccg
     4561 ggagcggcag ccccaagtct gccgcacgac tggcaaagga tccggtcttt atcagggtcc
     4621 ttgagcgctg catgtcctgg agaggagagc tgcacccgaa acccgggatc cttgcagatg
     4681 tcgttgcaga acagcttgag acctcgccgg agagcaggat catcatcttt gccacattcc
     4741 gtgacatggt ccagcagatc gtggatttcc tctcggaacg gggcatcccc tgccagcggt
     4801 ttgtcggcca ggccaccagg gacacggaga agggactctc ccagaagaaa cagatcgagg
     4861 ccctgcagaa gttcagggcg ggggatttcc gggtgcttgt cgcgacctcc gtcggcgagg
     4921 aaggactcga cattccctcg acggacctcg ttgtcttcta cgaggccgtc ccgtccgaga
     4981 tcaggagtat ccagaggaag ggacggacgg gaaggagcgg gaggggaagg atcgtcgtcc
     5041 tcgtcacgaa ggggacgacc gacgaggtct tccggtacgt gagccagacc cgcgagaagt
     5101 cgatgatcgc cgggatccgg cgcatgcacc acggaacggc ccccttcgag agcgttccgc
     5161 ggtcgcctcc tgccgtccag tcctcgatcg gggacttccc ggagaaaggg ccggtcgtga
     5221 aggtggatga ccgcgagacc tcatcccggg tcgtcgaggt cttaagcact ctccgcgtcc
     5281 agctcgcgat cgggaggctc ccctccgggg actatgccat cggggacagg atactggtcg
     5341 agagaaagac tgtcagggat ttcgtggaca cgctcgttga ccgggacctc tttgcccagt
     5401 taaaggtcct cgccgagagt gccccgcggc ccgtcctgat catcgaggga accgacgata
     5461 tctacaaggc aagggacatc cacccgaacg caatcagggg cacactggct gcaattgccg
     5521 tcgacctcgg catctcggta ctcttttcca ggaacgagga ggagacggcc cagatcatcg
     5581 ggatccttgc gaggcgcgag gagggaggga acagggagag gacacttcct gtccggaaaa
     5641 cggggtactc gctgcgggag caggcagaga tgatcatcgc ctcgtttccc gacatcgggc
     5701 caaagcacgc acgcgccctc ctcgagcact tcggctccgt ccaggcagtg gttaatgcac
     5761 aggaggagga tcttgtcagg gtgaagggaa taggaaagga acgggcaaaa aagatttggg
     5821 aagtctcgca ccggccctac cgctgatccg gttttccggc aagtttccgg aaagcgtccg
     5881 cgccggcctg cacggcctcc atcaggatct ttgcccgtac cgggtcctcc tcggcggctg
     5941 ctttttcgca gagggagacg atggcacgct cgagcgattc cttcatccgg aacccgtcag
     6001 gaatcgtccc ctctcctccc ccgactcctc ccggatgggg cggccgggtc agtcctgcag
     6061 caggctcacc tttttctgca ttcctttcgg tgcagacaac gcagagcttt tcccccctga
     6121 tctcgaagag cgggcagccg catgccgggc atgtcgccga gagcatcttt cctcccttga
     6181 ggaggtagcg ggccataatc tcgtcttccc gtttcgtctg cccttcacca gccatttttc
     6241 ccgacaccgc agtttcgcat ggtttatatg acttgtcctc tatataagta gtggttcagg
     6301 aatgactcgt tattgatgag tttttcatgc acgaccggag gggattgtca tgaccaaccc
     6361 tgaaaagacc atcgagaact gtatccagat gctccagcac atcatggatg acagcaccat
     6421 accgcgaaat atccggaggg tcgcagatga gacccgccag ctgctgatga ataattccaa
     6481 aaaaaccggg ctccgggcag ctgaagcgat atccaagatc gacgagatca gcaacgatcc
     6541 aaacatgccc gtccatgccc ggacgcgtat ctgggaactc gtctcccagc tggagacaat
     6601 cccgctggac tgaccctttt ttcgagtgag acacagcgaa aggctatggg gccacggccg
     6661 gcccccggat gaaaaccgca agcgccgttc tcatcctggt acccgtgtct tcggaagaac
     6721 ccggtgtgtt tcctggagac ggggaccggc gaagtgcggg tgtcgaccgc acatgcaggg
     6781 gtattgtttc gttccttcag ggcatgacgg tgatgatgac tgtcctgtcc ctttcctgcc
     6841 tgacatcgag ttcgaggaga acgacctgct gccacgttcc aagctcaggc tcgcccccgg
     6901 tcaccgggat ggaaagggag gggccgacga tggctgccct gacgtgggat cggccgttcc
     6961 cgtcgcccca tgcaccgtcg tgggcgtagg gaatggtggc aggtgcaatg gccgagagtg
     7021 cccggacaag gtctttgaga accccgctct cgtactcgat cgtggtcacg gcagcagtcg
     7081 atccggtcac aaagacgttc accagtccct cgcggacacc gctctcccgg accgcttccc
     7141 tcacgcgctg cgacagatca acgatgtccc cctcgccacg cgtcttctgg tggatcctcg
     7201 tctggtacat cgggaaaaag agggaaaaac gaggggatga atgtatcgcg accggcaaac
     7261 tccccggcac cagccgggaa aaaaggagac gggtgacttt attcctccat ctcgggacgg
     7321 aggatggcga acccgacgac gcggtcgcct tcctccatct tcatgatcct gactccccgg
     7381 gtgctcctct tctggatgga gatctccgag accttggtcc tgatgacgat ccctgacgca
     7441 ctcatgagga tgatctcgtc gttttcggag accgccttcg cgtccacgac accgccacgg
     7501 aactctgtca ggatgttgcg gacacccatc gttccccgcc cgtggccgtg gaactctgcg
     7561 aaatcggtgc gcttgccgta cccgttctcg gtaaccgtca ggaggtggtc cttctcgacg
     7621 agggagacag cccgcaggtc atcgttgccc ctcatcctga tccctatcac gcccattgca
     7681 cccctgtgat gctcggtcac ggaagattcg ctgaaccgga ggctctggcc cttccgggtg
     7741 gtcaggatga cctcgcgttt cccgtcggtg atcttgacgt caacgagctc gtcgccctcc
     7801 cgcaggttca tcgcgatgat ccctgtcgac cggggccggg agaactcctc gagcgggacc
     7861 ttgagcacca ttcccttccg cgttgcaaag aagaggaacc tgtcccgcga gaactcgcgc
     7921 accggtatca cagcggtcac tttctcgttg tcgaggttga gcaggttgac gattgccttg
     7981 ccgcggctcg tgcgcgaacc ctccggtatg tcgtacacct tgagccagta ggcccttccg
     8041 gtcgtcgtga agcagaggag gtaatcgtgg gtattggcga caaagacgtc ggtcacgtag
     8101 tcttcttcct ttgtcgacat cccgatgatc cccctccctc ccctcctctg ctggcggtag
     8161 gtgtcaaggt ccatcctctt gatgtagttg agcgacgtga gggatacgag cacctgcttg
     8221 tcctcgatga ggtcttccct gtctagctgc gtcgcctccg cggatatccg ggtcctgcgg
     8281 tcatccccgt atttctccgc gatcgcgacc agttccttcc ggatctcccg ccggatgttc
     8341 ttctcgtcgg cgaggatctc cgtcaggcgg gcgatctctt tcaagagttc gtctttttcg
     8401 tcctggatct tcttttgctc gagcgcagcg agcctgcgca gctgcatctg gaggatggct
     8461 gcagcctgtg gctcatcgag cccaaaccgc gtgatcagtg tctcctttgc aacatcagcc
     8521 gtctccgacg ccctgatggc agcgatcacc tcgtcgatgc gggagagggc gagcagcaga
     8581 ccctcgagga tatgggcgcg ttcctgcgcc ttcctccggt cgtactcgct cctgcggcgg
     8641 atgacctcga tcctgtgggc gacgaactcg cggaagagac ccgtcaggga gaggatacgc
     8701 ggctggttct cgacgattgc caggttgatg atgccgaatg tgctctcgag cgccgtgtgc
     8761 ttgtagagct ggttgaggat gattgcaccg gaggctcctt ttttcaggtc gatgacgacc
     8821 cggagaccct ccttgtccga ctcgtccctg atatcggaga tcccctcgat cttcttctcc
     8881 ttgacgagat tggcgatggt ctcgatgagc ctggccttgt tgacctggaa cgggatctcg
     8941 gtgataacga tccgttcccc ccggcttccc cggtcttcta tctcggcaac gcccctgatg
     9001 atgaccttgc cctggccggt gaggtaggca ctctttattc cctcggtgcc catgatgacc
     9061 ccgccggtgg gaaagtccgg gccgggaagg tgctgcatga agacctcgag gggggcatca
     9121 ggcgtgtcga ggtactggac gagcgcgttg cagacctcgc ggaggttgtg cggcggcatg
     9181 ttcgtcgcca tgccgacagc gatgccgctc gacccgttga ggaggaggtt tggtaccttc
     9241 gcggggagaa caacgggctc gttgagcgac tcgtcaaagt tggggacaaa cgcaacggtc
     9301 tccttttcga tatcgtgcag gagttcctct gcgagtgggt cgagcctcac ctccgtgtac
     9361 ctcattgccg ccggggcgtc accgtcaatc gacccgaagt taccctgccc ctcgatcagg
     9421 ggataccggt aggtgaaggg ctgggccatc ttgacgatgg tgtcatagat ggccgcgtca
     9481 ccgtgggggt ggtacttccc catgacgtcc ccgacgacac gggcactctt ccgggtgggc
     9541 ttgtcatggg tgttgcccat ctcccacatg gagaagagcg acctccggtg aaccggcttc
     9601 aacccgtccc gcacgtccgg gatggccctc ccgatgatga cgctcatcgc gtagttgatg
     9661 taggaggtct tcatctcctc ctcgatgttc accgggatga cctggcttgc aggctcctgg
     9721 cccgcacccg cggtgcctgc ctgctcagat gtcaaggttc gtcacctcgc gggcgtggcg
     9781 cttgatgaaa tcgcggcggg cggccacgtc ctctcccatc agcttctcga atatctcgtt
     9841 tgcgaaactt gcatcctcta tcgtgacccg cttgaggaca cggctggcag ggtccatcgt
     9901 cgtgctccac agctgccccg cattcatctc accaagaccc ttgtaccgct gcaccgtcac
     9961 ccctttctcg cccagctctt tcacgatctc cttcatctcc tcctcgcgga acgcatattt
    10021 ctcgactttc cccttggcaa cgcggaacag ggggggctgg gcgatgtaca cgaacccctc
    10081 ctcgatcagc ctcttcatgt accggaagaa gaacgtcagg aggagcgtcc tgatgtgggc
    10141 tccgtccacg tcggcatcgg tcatcaggat aacgcggtgg tagcgggcct tctccgggtc
    10201 aaactgctcg ccgactcccg tcccgatggc tgaaatgagg gcctggatct ctgcgttctt
    10261 gaggatcctg tgctgggtcg ccttctccac gttcaggatc ttgccccgca ggggcaggat
    10321 tgcctggaac cggcggtcac ggccctgctt tgcggaaccg cctgccgagt ccccctccac
    10381 gatgtatatt tcgctccggg ccggatcccg ctcggaacag tcggcaagtt tcccgggcag
    10441 cccggttgtc tcgagggtgc tcttccggcg ggccagctcg cgggcgttcc tcgcggcctc
    10501 gcgggcccgt gcagcagtca ggaccttctc cacgatcgca gagaggacac gcgggttctc
    10561 ctcgaagtag tccgagagcg actggtagac gagcgagtcc acgattccct tgacgttgct
    10621 gttgcccagg cgcatcttgg tctggccctc gaactggggg tttgcgatct tgacgctgat
    10681 gatcgctgtc aagccctcgc ggacgtcctc gccccggatg gagagcccgg tctcccggat
    10741 caggttgttc ttgcgggcag agttgttgac cgccttcgta atcgcgctgc ggaacccttc
    10801 caggtgcgtc ccgccctccc gcgtattgac gctgttgacg tacgaaaaga tctgttccga
    10861 gtatcctgtc gtgtactgga gggccacctc gatctctgtc atggactccg ggtcgttctt
    10921 tttcagcgag atgacgtcag ggtggagagg ttcggccccg gcgttgagga aacgcacgta
    10981 ttccgcgata cctccctcgt agtggaactt ctcgctgtca ccggtccgct cgtccaggag
    11041 cgatatggag atcccggcgt tgagaaacgc cagttcacgg agcctgtggg ccaggatgtc
    11101 gtaatcgaac ctgaccgtct cgaatatcgt ctcgtccggg gcaaacgtga tcagtgtacc
    11161 cgagaggcgg tttccgaatt tctggaggaa ctccgccctg tccgatccgc ggaacgcagg
    11221 tctcgaaccg taccattcct ggtaccgggc gataagttcc tcgatgctct cctcgcggga
    11281 cgcaagggga ctcgtgacac gcccccgttc gaagcgcatc tcgtagatgt ttccgtcccg
    11341 gtataccctc gcgtggagcc accgcgagag tgcattgaca acggagacac cgacaccatg
    11401 gagccccccg gagacctggt acgtgctctt gtcgaacttg ccgcctgcgt gcagcacggt
    11461 gaggacgacc tcgagcgcac tctttttcgt attgttcatc tcgtcgacgg ggatacccct
    11521 cccgttgtcg aggacggaga tggacccgtc gccgtgaatt gtcacccata tggatgtgca
    11581 gaacccggca agagcctcgt caatggagtt gtccactacc tcgtagacga ggtggtggag
    11641 tccccgcgta tcggtgctcc cgatatacat tgcgggacgt tccctgaccg gctggagacc
    11701 ctcaagtacc gtgatatgcg aagcatcata agtatctgcc attcttctcc cccgtcaaaa
    11761 aacacacttt ttccagcaga acgggcgtca catgtagtat tggacgcgca aacacataag
    11821 cctaattcag gaaaaccggg taattttact ggaattcgcc gagatccgga tcttttatcc
    11881 cgagcccctt gtcgatggca atgatcaggc ggttgatgag tttcttcacc tcttctgcct
    11941 cctccctgtc gagtgtcccc ggctggtgcc agacgatccg cttgcggagc ctgtccgcga
    12001 gttcctcgat ctctgtcccc ctgaactggt cgggaacgat gaactcttcc aggtggtctg
    12061 ctgccccgaa aaatgcttcc tcgggcttcc ccgagaagtg cttgcagatg tgcatgaggt
    12121 ttgtgatgaa tccccgtcca aacgcgcttg ccatgagaaa gagaggtccc ctcaaaggga
    12181 aaaagggttg cgatcagagc agtccctgcg aggacagcca ggcgatgacg ggggtgcaga
    12241 cgaccacggg catgcaggcc agaagaaaga acaggtccct tcttgcgagg ggcttcttcc
    12301 tgatgtagag gtggctttcg cgcccgtatc ccctgcagag catggccatg tacgtccttt
    12361 ctccctgctc gtaggaccgg atgaagagcg tgccgatggt atatgcgagg acacgcaggc
    12421 ggtaccggta cggcaggttc cggtcaaagg gcgagaagca acgggcggca agcgattcgc
    12481 caaccttacg cgtgatgtac ccgaagacaa atatgtaccg gaccatcatc ccgagtacga
    12541 gtgagaactc tgccgggaga ccgagcctgc cggccccctc caggaggtcc tggacacgcg
    12601 tcgtggagga gagcaggatg ataaacgata tcgagacgag gaatttcacg aacaggacag
    12661 aggcaaactc gacggactcc cggtagacat ggatcccgaa cgggaggtca gcaatggacg
    12721 tgtaaaccgt gtagtaaggg ttctgtacga atatctggac aaatatgaga aagaaaccga
    12781 aggggaccac catgaggacc ctctttccat agacgagggg cgagaggcgc gagagtgccc
    12841 agaggatcgc aaagaggagg aaaaagacga gtccgaccgg aaagacgacc ggcgagtacg
    12901 ggacggcgac catcgcgacg atcgctgcaa agcagaggat gatcttcgcc cgggcgtcga
    12961 tatcgtggac cgggcttttc ctgtatgcct gcttctcgat gaagaagagt tcctcgatca
    13021 tcccctcctc ccgaatgcct ccaggaaagc gttctttgcc tcgtcaaatg tgtacgccat
    13081 ggagatcccg accccttcct gccgcagcgc cccgatcaga cgtggaatga cagggacttc
    13141 gaggcggacg gatgccagca tctcgtgctg cacgaatacc tccctgcacg tgccgctcgc
    13201 aacaatcctt cccttgtcca tgacgtacac gatatcggcc atttcaggga cgagcgagac
    13261 gtcgtgcgtg gaatagatga ctgtcatgcc gaacctgcgg gcaagcgaat tgacaaagtc
    13321 cacgaggtca cggactccgg ccggatcgag ccccgcagtg ggttcgtcga gcaccagcac
    13381 ctgaggttcc attgcgatga tgccggcgat cgcgactctc ttcttctccc cgccggagag
    13441 gtggtggggg acgcggtcac gcaggtgggt gatcccgacc acgcggaggg cctcttccac
    13501 cctgtggcgg acagtctccc cgtcgagtcc caggttcatc ggaccgaacg ccacatcctg
    13561 ttcgacggtc ggagagaaga tctggtcatc ggggttctgg aagaccacac ccacgaactt
    13621 ccgtacctct tttacatttt cacgggtgat cggctcgccg cggatcagga tcgtgcccga
    13681 ggtgggctgg aggataccgt tgaagtgctt gaaaagcgtg ctcttcccgg ctccgtttgc
    13741 acctatcact gcaatgcgcg cgttgcgcgg tgcgatgaag ttcaccctgt caaggcccct
    13801 gacgtttccg gggtagacgt gacagaggtc ccgtgtctcg atgaggtgca tggaaagaac
    13861 cttaccccga acgggtgggg cgcaaaaaag taaataggta ttctttcatc ccgggcggga
    13921 aaaggctttt ccgagcccga atgcaacaag caggacgagg atcgtccctg ccacgatggc
    13981 aagggcctct cccatcttcg cgagaccttc gatggaataa tccgggaacg gtgccgcata
    14041 cgagaacgtg ttccccgtga tctcctgaac ctgttcctcg gcggcgactg cggcatcctc
    14101 gttaagttcc gaaccatgga tctcctttgc cccgaatatc ccgaagaatg cactctccag
    14161 gccgtccggg ttgctggatg cgatgaacgg cgctgcaacc gcgattacaa gggcaatgat
    14221 gatcccaaag atgaggatat tgtccttctt catcaggcgg tcacccccga ttccttcggg
    14281 aggatgtcag gtcgtgccgt aaagatcagg tagagtgcga cagtcgttat cgcgccctcg
    14341 atcaccccga tgacggcatg gtataagccc atggagaaga ggccgaggcc caggggaaac
    14401 gttcctgcaa tggccatctc gactgcgcag gcaagggccg aaacaaacag ggagagccag
    14461 gcagccacaa atgcagcagg atacgggttc ctgatggccc tgtttaatcc cttgtaactg
    14521 tagaacccga cgaatccccc gatgacaccc atgttgatga tgtttgcccc catcaccgtg
    14581 atcccgccgt caccgaacag gactccctgg acgatgagga cgagggtgag aacgaagacc
    14641 gctgcaaagg gtgaaccaag gacgatcgca gcgagggcgg cccccaccat gtgaccgctc
    14701 gtcccccatg gaatagggac gttgaccgcc tgtatggcaa agattcccgc cgcaagcacg
    14761 gcgacgagag ggaccttttc ttcacgcatc tcggcccttg cccaccgcag ggacagggca
    14821 atgaacacga gggcaatgac ccagtacact gctgcctgca ggagtggaat gaaactatca
    14881 gggatgtgca attgaatcac cagaataata ctcttacatt tgatagtttt acttattctt
    14941 taaaaaatgt tcttattgaa attttttaat accattgagc tgatgagcgt gccaacaagg
    15001 ggaaagagtt ccggcctcgt agcaaggcgg cggacaatct ttccgggccg gtccatgtct
    15061 cccagggaca cgatgtccct gatgatggca gggtcatcga gtgccctgat tatccctgca
    15121 atatcaccag gtgtcatttt ccggcggacc tcgaagagcc ggagcccaag agaaagctcg
    15181 cggccgaagt ctgctctcca ggccttctcg tagggggaca ggtcgtcatc gctgaatttc
    15241 cctttcctga cagcctcccc gatgacgtgg gcagcatgcc gcgctgcccg gacacccgtg
    15301 tagacgcccc cgcccgacgt gggcttggcc atccctgcag cgtccccgac gagcaggaca
    15361 cggttgccat acgtccgggc cctcggcccg atggggatcg ccccgctcac gaggtggacg
    15421 gatgcctgat gaccatcccc gaaaaaccgg cccaggaacc gcgggaaggt cgtcctgaca
    15481 tcccgaagac cggcgaggcc cacccgtgcc cttcccgggc cgatgggaat cgcccacccg
    15541 aagaagtccg gggaggcatc ggggtggatc tccacgagac cctcgtccat ccgccaggct
    15601 atgtctgcct ggaggccggc aaggacgtgc gcggggcgtg gcatgccgct ctcgcgggcg
    15661 acccggctcg ctgccccgtc ggccccgacg agaaccccga acgagatctc ttccttcccg
    15721 cgtatccccc tcgtaacgat gctgtgtccc tccctccgga agaacgcggt cttcatcctg
    15781 atctctgccc cggcccgggc agcacgcgcg agcatctcgc ggtcgaggat ggcacggtcc
    15841 accacgtggg ctttcggaac gcccgcatca aaggagagga cggggccaag cgaggagacg
    15901 atccgggcac ccctcaccgt cgcgatgatg cacgagtcag ggacactgca ctcttcgaat
    15961 gctgcgaggg agaggagtcc ggcacactgg acagggattc ctgcggatgc atgttcctcg
    16021 aggaggcaga ccgagaggcc ctgctctgcg cacaaccggg cgcacgtgct ccccgacggt
    16081 ccgccgccga ccacgacaac gtcgaagtgt cccgtcacgg ttttcccctt ccattgtcag
    16141 cacgtggcag tatcaaggga tctgaaagac cggagggact aaagaacggg agcagccggg
    16201 gatggaaacc acgggcctgc cggaacccgg actgccggca cattctccct cacacccatt
    16261 tttcacctcg cagggggaaa catactcccg cagatggaga gagaaccaca gtttgtctgg
    16321 aaacagtgca tcgtcgtccg gagcgatatc aggatgagct gcggcaagac gtgtgcccag
    16381 gtcgcccatg ccgcgatcat cgcgtacgag agggccgatg cagccacgag gaagaaatgg
    16441 ttccaggaag ggcagaagaa ggtcgtcctg aaggttcccg gggaacgcga tctcctggaa
    16501 ctcaagagcc ttgccgaaca ctccgggatc gcgaccggtc ttgtccagga cgcgggactg
    16561 accgagatcc caccgggaac cgtgactgcg ctcggcctcg ggcctgcaaa gagcgaggat
    16621 ctcgaccgga taacgagttc cctgtccctc ctgtgaaggc cggacaggtg gcacccgttt
    16681 ccggctgcgg gttccccgac aggaagaccg ttttatgaaa gagagcccct atcccctcga
    16741 aaagttcctc gggatgcgct actacgcgag cgatacaccg ggaaccggcg gcaggctgcg
    16801 ggagcgtgcg gaggactttg ctgtggacga ggtctttgcc gcaccgggag acgaggggcc
    16861 gtacctcgtc tgccggctga cgaagaggaa ctgggagatg cagcgggcag cccgcgagat
    16921 cgcaaggcag ctggggatat cgcaccgccg ggtctcgtgg acggggacga aggataccca
    16981 tgccctcacc acccagctga tcgccatcta cggagtccgg gaaaacgata tcgcacgggt
    17041 caccctcgga gacatcgaaa tagtcccggt cgggagatcg cagcagcccc tgtccctcgg
    17101 gggacatgag gggaaccgtt tctcgatcac catacgggac acgcggtcgt ccgaccccgg
    17161 ccgggagctt gcggaagttg cggagacgtg caggcaggga atccccaact acttcggcat
    17221 ccagaggttc ggggtggcaa gacccgtcac ccacctcgtg ggtctccaca tcctcaaagg
    17281 tgacctcgaa ggggctgtca cctgttacat cggcagggcc tgcccgggcg aggaccctgc
    17341 cgtgcgggaa gcacgcggag agttcctctc gtcccgtgac cctgccgctg ccctgcggtc
    17401 gtttcccgtg accctctcct acgagagggc aatgctccat cacctcgtat cgcacccggg
    17461 tgactaccgg ggtgcgctgt gttccctccc gccccggctc ctctccctct tcgtcagtgc
    17521 attccagtcc cacctcttca actgcaccgt ctcgtcccgg atggagaggc tcggcgatga
    17581 cttccggatc ccgcatgcgg gggacaggct cctctttcca gacggaaaag aggatgtcgt
    17641 ctcgtccccg atgctccagg ctgcccgcac catggcctcc aggggcaggt gccgcgtcgc
    17701 gatcatggta ccggggtcgc ggcccgttca gcctgccggc gaggacgatt ctgcgatggc
    17761 cctcctcctt gccaggcatg gcatctcccc ggaagatttc gcacgggcct cggagatcgt
    17821 ggggacccgg tacaacgggg cgctgcgacc ggcagtcctc tccacggacg ttgcatggac
    17881 tgttgcggga aaggacgtga ccctcacttt ttccctcggc cccgggagtt atgcaacgac
    17941 cgtgtgcagg gagttcatga aggccgaccc ggcctcgatg gtctgacggg gagagttcag
    18001 ggtttccagc cggctgcaag cttccttgct ccctcgatgg catcgttgag gtttcccagt
    18061 tcgtcaacga ggcctgcttc gagggcatcc tgtccgcgga acacccgtgc gtcctcgata
    18121 atactccggt tgaccggccg tgcggcaagg atcccggaaa ggatcccctc gttactctcg
    18181 ttcacgatca taccggcata ctcgcgctcc tcgggcgaga ggggacggta cccgtatccc
    18241 atatccttcc tgctccccga ggtaatcacc tcgacactga tgttattctc cgcaagccag
    18301 tccgatatgt caataaatgt ccaggatgtg ccaatcccgc ccgtaatggt gtcggggttt
    18361 gcgtagatgc ggtctgccgg tgcagagatg gcatacgccg cggaggtggc aatgtcaccc
    18421 atggagacga caaccggctt cttttccatg gcatacctga tgtcccggat gatctcctgg
    18481 gcagcggcag gggtgccgcc gggactgttg acgcgcagca ctatcgcttt gacgagggga
    18541 tcgtcggctg catcccggat cgcccggccc gcgtattccg agccggtata accccctccg
    18601 tggcccgtgc cggtcacgat ggtcccctcg atacggatga ccgaaatccc catctcctgc
    18661 gtgtcagacc actggaggag ccagaatgcc gcagctcccg caaggaatgc caggagcagg
    18721 agaagagcga atacgaaaag gcgccttacg ggcttttggc tatgtcccgg aatctcctcc
    18781 acttgtgtcc cctcctttcc ctgaatagag gaccctccac tctgtcacga ggttcgtgcc
    18841 gcacatgtaa tgggacgaca gggccagccg gatcatctgc gactcgtcct cgatgtgcat
    18901 cccgccgaca agcgagggcg tgtcggctcc cccgacgatg aaggggaggt ggatgagccg
    18961 gatctcgtcc acgagccggt ggtgcagcat gtgccagttg agagtggggc ctccttcgag
    19021 catcatccgc cggacaccga actcatcgtg cagcttctcc atgaggagcg gcaggtcgac
    19081 atggtcttct ccggcaacga cgacagaaac tcccctggcc cggagcatcg ctaccttttc
    19141 ttccggtgcc cgggaacaga cagcgatgac cgtgggtgca tcgggcccga ggacgtttgc
    19201 atccggggga atatctgcca tgctgctcgg gatgacccgg agggggctct tcccggggac
    19261 cagccggact gtcaggaacg agttatcgat ctgtatcgtc cgggaaccga ccatgattgc
    19321 atcgcaggcg gcacgcgttt tgtgcaggag gatctcggtc gcatggtcca tgtatttcat
    19381 caggattttg ctggatgctc ccctcttgag ggtgagcttc ccgtctaccg tgatctctga
    19441 catcatcagg acatggggcc ttcttctgtt ttccggcacg aaatctcccg ccacagagag
    19501 ctgtatcgtg ctgctctgat atagaggttc cccggccggc aagagactgc aaagccgcct
    19561 ttatcctgaa aaatccggtt attttcccca taggggctgt caccagccgg gaatgataac
    19621 cattatccgc agtcccggca tggtacttag gcatgaacat tactgccctc cggccccgtt
    19681 tcatgcggta catcgagccg gtggcagcac tcttttcacg ggcgggtttt tcggcaaacc
    19741 aggtctcatt ccttgcgctg gtctttggta tcctctgtgc cattctcttt tccctccgga
    19801 tgtttcccgc cggcagcctc gccctctttg tctccgtgct gctcgacctg gtcgacgggt
    19861 cagtcgcacg ccagacatcg acccagtcac ggttcggggc ggtttttgac tggatcgtgg
    19921 ataagtacgt ggatgccctc gtcattgtcg ggataggcgt ctccggtgtc ccgctcgtca
    19981 cgcgtttcct gtcccttccc ccgacagccg atttctgcgt tgtcgccctt gccgtcaccg
    20041 ggtccctgat gaacaccttc atcaagccgg tggtctacgc cgagatcggc taccaggaga
    20101 gggtcgacgg gaagatagaa gaccccctcg agggtgtcgg gttcttcggg agacccgaga
    20161 cctgcctcgt cctcctcatc ggaggagcaa cggggttcat ctggatctcg gtcatcatca
    20221 tcgctatctg cacgaacctc tccgcagtcc agagaatcac gtacctctac cgaacgctcg
    20281 cctgatctcc ctgatataga ggtcaacgag gtccgtggca taccgtgcca gatccgggat
    20341 gatggaaaag agtccccatg ctattccgat gaggaggaga agtgccagcc cctcggcgat
    20401 cacgttgtgc gcccagaaga aactctcgta ccccggttcc ccgttgcccg caatctccgg
    20461 caggtagggg aaccactgcc cggaataggc aatgatgacc ccgacgttcc tcgcgatgtt
    20521 gaggaggtag atgacaggga cgatgagcag gaacgagaga accttctggc ggaacgtcgt
    20581 cctgacagcg ctgaccacgc cgagcatgat ggctattgcc tggatccccg tgcaggcgag
    20641 gatgatctcc acccggtaac cgttccggga gacgaggttc cacgcgagcc ggtcgacggg
    20701 gtacccgaca agagagagaa cggccgccgt ctggtccacg acgaccgcga tcagccagtc
    20761 accgagcggt gtaaattcga aaggggcata aatcaggaat gcaaccgctg cagccgtcga
    20821 gagctgccgg accagccgct ctccggaaag gaggtttttc ccggttattg cgaggaaggg
    20881 gacggacagg accgcgagga cgggatagag gacgttgttt atggaaaggt aataggggat
    20941 ttcggcaaag aggaagagaa ccatccccgt ccacccgagt accgcacagt gattcctgta
    21001 acgccatgga accaggaatg caaggaaaaa gatgcaggag aagaggacga ggagctcttt
    21061 catcccattc ctatgggtat cccgaaaaga aaaaaggtgc tattacgaat ggtttgaccc
    21121 cgggacaact gcgtctcgtc actctccgga caggccatcc cttttttttt ggaccttctt
    21181 taccttcttt tatacaagcc ttaatctcgc atggaggcgc attaatggct gatgttctgc
    21241 cctgaatgcg gaagcctgat gatctcgtct gcaggccagt tgaagtgccg gaaatgcggt
    21301 tacaacagga aaattgacaa gaatgaccag atgcagatca cgaggacacg ccgcgagaag
    21361 gagatcgtga tcgtcgagga ggaaggatct gtccgcactc tgcctacaat cgcagtaaaa
    21421 tgccccaagt gcgagcataa ccttgccttc tggtggctcc gccagctccg ggctgccgac
    21481 gagagcgagg tccggttctt caggtgctgc gagtgcgggc acacgtggcg ggaatacgac
    21541 tgatatccag ccggtccttt tttctatcct tttatcccga ttgtgaccgg aatacacgga
    21601 accggaatat ttggacgaca gggctagtga tggggaacac gtcatgacac aatccccggt
    21661 caaccctg
//
LOCUS       DAOOJU010000026        20353 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2638_length_20353_cov_14.748842, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000026 DAOOJU010000000
VERSION     DAOOJU010000026.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 20353)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20353)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20353
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2638_length_20353_cov_14.748842"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(41..229)
                     /locus_tag="PK679_07050"
     CDS             complement(41..229)
                     /locus_tag="PK679_07050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55749.1"
                     /translation="MDQDTIHDREAILRITSKAIDILNRRFHSAQGTEVVALAEQLRE
                     MARLHMELQERAIGTPEG"
     gene            complement(311..826)
                     /locus_tag="PK679_07055"
     CDS             complement(311..826)
                     /locus_tag="PK679_07055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin"
                     /protein_id="HPC55750.1"
                     /translation="MTPWDKDRGSSNPLATILLVAITLLLALLVLLLCPSLQFDFGEV
                     MKPPSFIEIRSIIHTNDQGTLTYDSKVVLFHNGTKSYPNDDLTATFYKNGQKVPCVIE
                     TLNGFKFIKTHHFGVQTMSGTGCREDKWNPHEKIAIDFADGTFHPGDTITVEIYQKPK
                     NILISRFSKTG"
     gene            complement(1125..1472)
                     /locus_tag="PK679_07060"
     CDS             complement(1125..1472)
                     /locus_tag="PK679_07060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HPC55751.1"
                     /translation="MKEMVSMMMICAVIRPERLEFIKKDLEKAGIYGMTIFDVQGRGD
                     QKGIQLQYRGGTMNVDLIPKIMVEVVVPDGKLEETVGIITNAARTGKVGDGRIFVLPV
                     MKSFRIRTGEEIH"
     gene            complement(1469..2665)
                     /locus_tag="PK679_07065"
     CDS             complement(1469..2665)
                     /locus_tag="PK679_07065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HPC55752.1"
                     /translation="MAIDSGTTAWLLISTALVMLMTPAVGFFYGGLVRRKNFISMVAL
                     SFIVFALVSIQWVILGYSLAFGGDIGGLIGNLQHFGLEGLDPGQGDTAYPPLLFVAFQ
                     LVFATVTMAIVTSGFAERVRLSAFILFVLLWTTLVYDPLAHWAWGGGWTMGLGSLDFA
                     GGTVVHISSGFAALAVALVIGKRAGFGQYTMEPHNIPMTLLGAGLLWFGWFGFNAGSA
                     LAANGLAANAFLVTNTSAAAGALSWLFASWIRGKPSSLGMVSGAIAGLVAITPAAGFV
                     TVPASIVIGVAAGLLCYACMLWRINRGLDESLDAWSIHGMGGLWGAIATGVFAAAAVN
                     GFSGLIEGNVQQFVANVIGALAALAYAFVVTYILAFVIDRVIGLRVSEEEEYVGLDLS
                     QHGERV"
     gene            complement(2940..4268)
                     /gene="glnA"
                     /locus_tag="PK679_07070"
     CDS             complement(2940..4268)
                     /gene="glnA"
                     /locus_tag="PK679_07070"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HPC55753.1"
                     /translation="MRKNTVSEMLEKIENDDVKFLRLQFTDIQGMPKNVAIPVQQAEK
                     ALTEGIWFDGSSIEGFARIEESDMLLKPDPATYAILPWRPAEARVARFICDVYTYGNK
                     PFEGDPRHVLKNQIEQAKKMGFTFNTGPELEFFLFKMVDGRPSTNYQDYGGYFDLAPT
                     DSAEDVRRDIVFALTQMGFEIEASHHEVAESQHEIDFKYSDALDTADKVITFKFATKT
                     LALARNLHATFMAKPIAGINGSGMHTHGSLSRNGKNAFYDPNAKDGLSDVAMYYIGGI
                     LAHAKAITRVANPTINSYKRLVPGYEAPVYITWSATNRSALVRVPAARGNSTRAEFRS
                     PDPMCNPYLCFAAMLAAGLDGIKKKIMPPESTDVNIYHLTEAERKKRGIEMLPGSLIE
                     ANAALNNDPVISKAMGPHIMEGLNSIAQLETDLFRLAVHPWELDRYLAIY"
     gene            4382..5434
                     /locus_tag="PK679_07075"
     CDS             4382..5434
                     /locus_tag="PK679_07075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase family protein"
                     /protein_id="HPC55754.1"
                     /translation="MCGIIAVIDRAGCPMDGTKIRSALSMMDERGSGEGAGYAVYGAF
                     PEFADYYAIHVFFDAVHESKAAVDRELGNWGTVVHEEEVPTYENRNIRKVHTPWRYFF
                     KPDPSLMPRSETPEDDIVMHLVMKINTTIPGALVYASGKNVAIFKASGWPEDVADFYR
                     IQDYSGYIWLAHNRYPTNTPGWWGGAHPFNLLGWSVVHNGEITSYGTNRRFIESYGYR
                     CTMYTDTEVVAYLFDLLVRRHGLSPEMAVKALAPPFWDDIDRMNEKERTFYTAIRLAY
                     GSAMMNGPFAIVVAQRDGIVGFTDRIKLRPLVCGTAGSRLYISSEESAIRTMEHDPEE
                     VFMPRAGEPVIGRLGK"
     gene            5431..6939
                     /locus_tag="PK679_07080"
     CDS             5431..6939
                     /locus_tag="PK679_07080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HPC55755.1"
                     /translation="MTIGSVPVRFRITVDGSRCMLCGRCVENCPYDVFRKESDTIHVN
                     SRKCVACHRCIAMCPRDAISIKERPVDYRSHPVWTEEARESIYNQARTGKIILAGMGN
                     AKPYPVIFDSLVLDACQVTNPSIDPLREPMELRTYIGKKPGRLEFRDDGDCQSLVTTL
                     APNLELATPIMVGHMSYGAISLNAQKSIAMAVRESGTFMGTGEGGLHPSLYPFQDHMI
                     VQVASGRFGVDINYLERGAAIEIKIGQGAKPGIGGHLPGEKVCEDVSSTRMIPVGSDA
                     ISPAPHHDIYSIEDLKQLVRSLKEATEWKKPVFVKIAAVHNSAAIAAGIARSSADAVV
                     IDGFRGGTGAAPRVFRDHVGIPIEAAVASVDAKLRSQGIRNEVSIIASGGIRESADVA
                     KVIALGADAVYIGTAALVAMGCRVCGTCYRGLCPWGIATQRPDLVARLDPEVASRNVA
                     NLIHAWTLELSELMGAAGINSIESLRGNRDRLRGYLLDESIMRVLDVKPVGA"
     gene            6947..7690
                     /locus_tag="PK679_07085"
     CDS             6947..7690
                     /locus_tag="PK679_07085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55756.1"
                     /translation="MTRVTIDAAGMHYTPLNRRIREAIGAGADEIVITGVMGQRFIAD
                     GVRGRGTIIIHGIPGGDLGMFMSGPTCIVYGNCDHAPGNTMDSGTIIIHGSAGDAVAH
                     SMRGGRVFVRDNIGYRGGIHMKQYQDKCPVLVIGGEFRSFLGEYMAGGLILALGDPGK
                     NSGRERGIGSGIHGGRIIIRGGPLDDRCLGVGAAQRPLSGEGYRQIQPIIREFADVFS
                     LDPDPLLRDRYIEIVPSSSRPFANKYTWE"
     gene            7696..8721
                     /locus_tag="PK679_07090"
     CDS             7696..8721
                     /locus_tag="PK679_07090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Coenzyme F420 hydrogenase/dehydrogenase, beta
                     subunit C-terminal domain"
                     /protein_id="HPC55757.1"
                     /translation="MVAEHSYVDLQREVWERGICAGCGACVAVCPADAICFDEPGGAL
                     RPRNIGYCKKENDEVPCGACYDACPRTGPAVPEEWENYRDILSARATMEIPGKQAGGA
                     VTAILSASLEQGLIDGVVTVTADRMTLLPRSVVLTSAGKVRETAGSRYNWWVPLVAAL
                     KTAVIDMKLGKIAIVGVPCVIRAVHQIRTSDNDLLKPFGSRIRLSMGLFCTETFDYRV
                     LVGEILGKRHNIGTTDIDRIDVRGKLEVTTRKKEKIAFPMSELKEAIRPGCHFCTDFT
                     AVHSDISAGAVGSPPGYTTLIVRTVEGQVFLDQALALGSLERGPGVNLEAVGKLAAAK
                     ISRARKI"
     gene            8790..9476
                     /locus_tag="PK679_07095"
     CDS             8790..9476
                     /locus_tag="PK679_07095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55758.1"
                     /translation="MKSSILIAGFLVFMIASWAVSAEEVPLLPAETGFPQPMIPHSFY
                     GSITAAGSPVPAGVPVEIDAPGIKKGIPENPVYSNEGGYGSPDPFRLRLAAQGTMEPG
                     TELVFYVGGVRAEVRPSGTENEWQSSFAYSPGGVTSLDLRVSVPVTPDPAFRMTPEET
                     SSQPVKTPPHGQSGPSQEVMLGLVAILVILAITAFFLGKRAEKKEKKSGGEEGTIQQG
                     GSPPGDEKQE"
     gene            9914..12004
                     /locus_tag="PK679_07100"
     CDS             9914..12004
                     /locus_tag="PK679_07100"
                     /inference="COORDINATES: protein motif:HMM:NF012340.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin like domain-containing protein"
                     /protein_id="HPC55759.1"
                     /translation="MSAPLFSPEAQQEFEDIREAIRKYKVAPANRDFKDSIARLKSLN
                     SSGNSDGKGNGDDSLGLIPSPIDVVFLTSVGSRDYAGNTAGSGTAPLLQASGYTSAYA
                     PATFDLRSTGKLTPVREQGQCGACWAFSSYGSLESTNLPGSMWDFSENNMKNSHGFDL
                     SPCQGGNYLMAAAYLARWAGPVSESADPYQESGTRRVQNAPVLEHVQEISFLPSRQGA
                     LDNAHIKQAIRENGAVYSSIHWEKSYYSPGTYSYYYPGSSIQNHAIDIVGWDDTYSRF
                     QFAVTPPGDGAFIVRNSWGEDWGERGYFYVSYYDTIIGKELIQFFPEETSNYDRMYSY
                     DPLGWVTSIGAGDGTLYAANVFSASGNEELRAVSFYTPVKGTSYEIEVSKNPSAGPRG
                     QYSQMVSAGTFPYAGYHTVALNNPVILEKGEKFSIIIRLTTPGYGYPLAVEYPMTGYS
                     TQAVAHSGESFISTDGKTWTDLTRVVQNGNACIKAFTVTRKSATPTPTPTPTPRPTPT
                     GTTVPATTPTLPGPGDTKSPTVTIVSPRLMSSFSPGDTIQVIWSARDSGGIASVRVEY
                     SLDGGSSWILLQTATSEAGTCSWKVPDTCPAKVTFRVTAVDNAGNAASASRVVTVRTT
                     TGKPGAGFPGIKTPPVFQREGNGADISGQANPQAISVERKEYSISPKVSAPVQSMVSL
                     KKGSQEGTTRSRLF"
     gene            12169..13104
                     /locus_tag="PK679_07105"
     CDS             12169..13104
                     /locus_tag="PK679_07105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC55760.1"
                     /translation="MVLFITGRCSRTCWYCPLSAQRKGRDDVYANEKKVQTPGEAISV
                     ARTMDALGTGVTGGEPLLVPGRVREFCMELKKEFGEEHHIHLYTGLAPGKDELGALCG
                     LVDEIRMHPPQEEWHRIGESAFLHSASLAREMGFSAGFEVPALPGIEGLRDALSALDF
                     LNINELEWGETNADAMRKRGMEPADDLHNAVSGCRDWAAPLLGHPKVHWCSSQFKDSH
                     QLRKRLIRVARNTARPFDHVTDDGTIIYGVIRGGGSIPEILSRLDREMYEVRDGEIET
                     LWWIVSEYSAEIGGEKCIIERYPDRGIIVEVTPVP"
     gene            13101..13874
                     /gene="uppS"
                     /locus_tag="PK679_07110"
     CDS             13101..13874
                     /gene="uppS"
                     /locus_tag="PK679_07110"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HPC55761.1"
                     /translation="MIEDAILSFYERILRMQCRHIPSHIAIIQDGNRRFARTRNMPRS
                     EGHRAGANRTEEMLSWARDLGIKHITLYSFSTENFNRDSEEVQDLFCLFKDKLSRVIS
                     DPRVHRDGIRVQVVGDRSLLPPDLQEAIARAEEATKHYDKYFLNVALAYGGRNEIVRA
                     AQRIIGGVSRGEVSLQDITPEFVESQLHEGQNIPPVDLIIRTGNEYRTSNFLPWLANG
                     HESAVYFCAPYWPRFRKIDLLRAIRTYSQRIDAMGKASC"
     gene            complement(14139..14783)
                     /locus_tag="PK679_07115"
     CDS             complement(14139..14783)
                     /locus_tag="PK679_07115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl diphosphate synthase family
                     protein"
                     /protein_id="HPC55762.1"
                     /translation="MIHWLYERHLIGGLRILPAHVCFMITGEEQKEAPEKLTEVCRWC
                     IETSDTIGQKRDQVRGDEENCVIRGVTFHISTNDPDEIGPLLPGIRDISRFARLTLHY
                     GDKTEVAGSGMNVHVAIGKSGREEITECIRRIAGKGIPPDQVNEHTIEEHLTFRYTPD
                     LVIKTGGSHLTDFLIWQSVYSELFFSDVNWSLFRKTDFLRALRDYQSRMRRFGR"
     gene            complement(14780..16462)
                     /gene="polX"
                     /locus_tag="PK679_07120"
     CDS             complement(14780..16462)
                     /gene="polX"
                     /locus_tag="PK679_07120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="HPC55763.1"
                     /translation="MSNREVAEKLSLMGEILEILDENPFKVRAYRRAAESIERLGVPV
                     GTLSPGELEAVPGIGTAIAKKVREIIATGTFHELEEARSSVPASLVEMLALDGVGPKT
                     IKTLWKKLGIQSIDDLERAARGHRIRAVRGFGPRKEQAFLEAIENYRQPRARMTRLFA
                     DQVIEGIRGVFAEGTFVVAGSYRRKKSTIGDIDIVTVDSPPSVNSRIRQIAEEVIDEG
                     DKKTSFRFKKTRIDVRFIERNRCGAMLLYLTGSKAFNIRLREIALERGLKLNEYGIED
                     AGRGKVHSFAREEEIFSFLGMDYIVPELREDWGEIQAAFSHTLPRLVDEKEIRGDLHV
                     HSTWSDGHMDIEGLARAGESLGYAYILCTDHSASLGIAHGLDEEAIRKQAHEIEIANR
                     SSSCQVLHGIEVDILADGTPGLPSRVLADLDIVVGSVHSGFSQDQDVMTRRVITALEN
                     EHIDILGHPTGRLIGEREPFAIDIHRVIEAAATHGKALECNASPYRMDIDDTAIREAV
                     DRGVKVALGTDAHDASELGWIRYGIGICRRGWATPGTLLNCMEQKDLLEWAS"
     gene            complement(16585..17145)
                     /locus_tag="PK679_07125"
     CDS             complement(16585..17145)
                     /locus_tag="PK679_07125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006935 - chemotaxis [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HPC55764.1"
                     /translation="MTAKESGETMEKPAAPVGKKAVQGAGGSSGTLQVVEFLLGKEHF
                     AIDLFDVKEVVEYTTITKLPNTPPYVKGIIDLRGEITTIVDLKQRLHITDESSQPEEN
                     SRIIVLDEKNTKSKIGIMVDDVLSVSTFDLKDVDTKSASEIGEDMSILGIIKKSIKEK
                     DTDKAVNELIIWIDIKQLLKDIDQHI"
     gene            complement(17163..>18023)
                     /locus_tag="PK679_07130"
     CDS             complement(17163..>18023)
                     /locus_tag="PK679_07130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HPC55765.1"
                     /translation="IEEVSAGSAQVAKNAAAVSTNAEQSNQGITEVLKAMEDLSRTIQ
                     QVAAKAESVSQLVQETNDYSRKGIELAKKTEGGMNGITRSSNEVNTIILEIKSQMDKI
                     GEIVNLITDLANQTNLLALNAAIEAARAGDAGRGFAVVATEVKSLAEESRISAEKIAE
                     MIGNLQKQTQTAAETVAISNNEVKEGSVALKETLENFNRIVESIDQISRNVTEVAAAS
                     EEQAASVEEVTASINEVNSLVRNTAKEATDSAAVSEETAAAIDQIAKVIANVNNIVVR
                     VSTEVSKFRI"
     assembly_gap    18024..18123
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<18124..19184)
                     /locus_tag="PK679_07135"
     CDS             complement(<18124..19184)
                     /locus_tag="PK679_07135"
                     /inference="COORDINATES: protein motif:HMM:NF028510.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cache 3/Cache 2 fusion domain-containing
                     protein"
                     /protein_id="HPC55766.1"
                     /translation="MIRLRGFSQMKIGTKVLIICLVLVTVPTLLLGLVAYTSSSTAIS
                     GQVDTLLSTEISDIQKMTANTYDLAQQKVNGDLNVLRSTFYGYGTPEISGGKLVLRGQ
                     GSREFVVNDNFEIVDQIERMTGSKATIFQKTGGQAIRISTNVVGADGKRAIGTPVSDA
                     VYDAVIVKGQTYYGTADVVGKTYITAYEPIKSSSGEIIGILFVGVPEDSVYGGLKKEI
                     LGVKLGQSGYVYVMDSKGTLLVHPSLQGQNMADQEFIQKMIANKDKVRDKPAKLEYVW
                     EGKNIDAYYMYFPALDWIIASRVDPADFMAPIDEIRNAIIIILVASIAVGALISLMFG
                     RSIARRMGDLVTLGNQVMDG"
     gene            19440..>20353
                     /locus_tag="PK679_07140"
     CDS             19440..>20353
                     /locus_tag="PK679_07140"
                     /inference="COORDINATES: protein motif:HMM:NF020897.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC55767.1"
                     /translation="MVERGDTDRIKELLGQHRNGLTIDEVSRHLGINRSTASKYLNLL
                     VSSGAATIRKLGPAKLFYLKERVPVNQLLNCTYDGIIIVDGKYGIHYINDVISTLFGI
                     GKESVIGSVALQTPLAPLFDPETQQFMGESLTREGHETRGTVRIGEKTFSIRKCIIPV
                     QFESGSTGYCLICHFDQGQVEQKASGLEKALPDMALYTQYYQLDALIRRYAKNQVTTA
                     LEILKKMEKSRDPARFREFAGEQEDLLKGILVHLMIFDEFLEETPPRQEWVHLEEVTG
                     NALSLVRLSHVRFFSDIRGIEIFADRSF"
BASE COUNT         4471 a         5558 c         5782 g         4442 t
ORIGIN      
        1 tttacatccg gcacatctcc tccagccctg ctcttctatc tcacccttcc ggtgttccga
       61 ttgctctttc ctgcagttcc atgtgcagcc gtgccatctc cctgagctgc tctgcaaggg
      121 ctacgacttc tgttccctgg gcgctgtgaa acctccggtt caggatatcg attgccttcg
      181 acgtgatgcg gaggatggcc tcccggtcat ggattgtgtc ctggtccata cccagccctc
      241 tgcatccggg gtcaataact ttgctccacg attcaccctg tcttttgggg tggagagaga
      301 atgacccggg ctatcccgtt ttgctgaagc gggaaatcag tatgtttttt ggtttctggt
      361 aaatctcgac ggtgattgtg tcgccggggt gaaacgtccc gtccgcaaaa tcaatggcga
      421 tcttttcgtg ggggttccac ttgtcctccc tgcaccccgt tccgctcatc gtctggactc
      481 cgaagtgatg cgtcttgatg aatttgaaac cgttgagggt ctcgattacg cacgggactt
      541 tttgcccgtt tttgtaaaag gttgctgtca gatcgtcatt gggataggac ttcgtcccgt
      601 tgtgaaagag gactaccttg gaatcgtaag tgagggtacc ctgatcattt gtgtggatga
      661 tggaccggat ctcgataaag gatgggggtt tcatcacctc gccaaagtca aactggagac
      721 tgggacacaa gaggagcacg agtaaggcga ggaggagagt gattgcgacc aggagaatgg
      781 ttgcaagggg gttcgaggat cctctgtctt tatcccacgg agtcaaactc ttgaaagtgc
      841 accgggtaaa aatttaagaa ttgtgattca tggtgtcccg ttgctctaac atgcattggg
      901 agatgaaaac ggtcgctcct tttggagagg acagcagtat ccactccggc ccgaaagtat
      961 cttccctcaa aatggttttt gaccttccat cggtccgaaa ctattgatag ggtcaacccg
     1021 gataccagca gcattcctgg ataaggaaaa aaactctgcc ctaaaaaaca gtgacatgaa
     1081 atgattcgtc gaaaatgaga ttattcccgc gggaaaaagg aggatcagtg gatctcttcc
     1141 ccggtcctga tcctgaaaga cttcatgacc ggcaggacaa agattctccc gtctccaacc
     1201 tttcccgtcc gggcagcgtt tgttataatt cccacggtct cttccagctt cccgtccgga
     1261 acaaccacct ccaccatgat cttggggatc agatccacgt tcatggttcc gccgcggtac
     1321 tgcagctgga tgcccttctg gtctccccgc ccctggacat cgaaaattgt cattccgtaa
     1381 atccccgcct tttcgagatc tttcttgata aattcaagtc tctcgggacg gataacagcg
     1441 cagatcatca tcatggatac catctccttc atactctctc cccgtgctgg gagaggtcaa
     1501 gcccgacgta ttcttcttct tccgaaacac gcagtccgat gaccctgtcg atgacgaagg
     1561 caaggatgta cgtgacaacg aaggcgtatg caagagctgc aagggccccg ataacgtttg
     1621 caacgaactg ctggacgttc ccttcgatga gaccggagaa accgttgaca gcggcggcag
     1681 cgaagacgcc cgtcgctatg gctccccaga ggcctcccat gccatggatg gaccaggcat
     1741 cgaggctttc atcgagtccc ctgttgatgc gccagagcat gcaggcatag cacaacaggc
     1801 cggctgcgac accgattaca atcgaagcag ggacagtcac gaatccggct gccggcgtga
     1861 ttgccacgag gccggctatg gcaccactca ccatgccaag cgagcttggt ttgccccgga
     1921 tccagcttgc aaagagccac gacagggcac cggccgcagc tgacgtgttc gtgacgagga
     1981 aggcatttgc cgcaagcccg tttgctgcaa gagctgaccc tgcattgaac ccgaaccagc
     2041 cgaaccagag gagacccgcc ccgaggagtg tcatcgggat gttgtggggt tccatcgtgt
     2101 actggccaaa accggccctt ttcccgatca cgagggcgac agcgagtgct gcaaacccgg
     2161 aactgatatg taccactgtc ccgccggcaa agtcaaggga gcccaatccc atcgtccagc
     2221 ctccacccca cgcccagtgt gccagggggt catagacgag tgtcgtccag aggaggacaa
     2281 aaaggatgaa tgccgaaagg cgtaccctct ctgcgaaccc ggatgtgacg attgccatcg
     2341 tcaccgtcgc aaagaccagc tggaatgcca cgaagaggag aggcgggtac gcagtgtctc
     2401 cctgaccggg atccagtcct tcgagtccaa agtgctgcag gttgccaatc agccccccga
     2461 tgtccccgcc aaatgcaagc gagtacccca gtatgaccca ctggatactc acgagggcaa
     2521 agacgatgaa ggagagggca accatcgaga tgaagttctt cctccttacc agtcctccgt
     2581 aaaagaaacc aacagccggt gtcatgagca tgacgagggc agttgatatc aggagccagg
     2641 cagtcgtccc ggaatcaata gccatctttc ttctccgttt tttgaaatca aacgtcagtg
     2701 cgggtgtccc ccccggggac catcctcacc ctccccgttt gacagataga aattttgttc
     2761 cacattataa aaaattatct ctctttgttt cccgaacctg tttttgcttt tcattttttc
     2821 ctgtatggtg actggagcgc atagacgaga gaagcggaag aatttccaac cggaatgatg
     2881 atttttcaat aatgaggcgg agtcatgaat tgaatgatgt atggaaaaaa agggattttt
     2941 tagtaaattg cgagatacct gtcgagttcc cagggatgga ccgcgaggcg gaacaggtca
     3001 gtctccagtt gtgcgatgga attgaggcct tccatgatat gcggacccat tgctttggag
     3061 atcacaggat cgttattgag cgctgcattt gcctcaatca ggctcccggg aagcatctcg
     3121 attccgcgtt tctttctttc tgcttcagtc aggtggtaga tattgacgtc ggtactctcg
     3181 ggcggcatga tctttttctt gattccgtcg agacctgcgg caagcatcgc agcaaagcag
     3241 aggtacgggt tgcacatcgg gtcagggctc cggaactcgg cccgcgtact gttgccccgg
     3301 gcagccggta cccggacgag tgctgacctg ttcgtggcac tccaggtgat gtaaaccggg
     3361 gcttcgtaac cgggcacgag tcgcttgtag gagttgatcg tcgggtttgc gacacgcgta
     3421 attgcctttg catgggcgag aatcccgccg atgtagtaca tcgcgacatc cgagagaccg
     3481 tccttcgcgt tggggtcata aaaagcgttc tttccattcc gcgagaggga cccgtgcgtg
     3541 tgcatgccac tcccgttgat acccgcgata ggtttggcca tgaacgtggc gtggaggttt
     3601 cgtgccagtg cgagagtctt ggtggcgaac ttgaaggtga tcaccttgtc agcagtatcg
     3661 agggcatcgc tgtacttgaa atcgatctcg tgctggctct cggccacctc gtggtgggat
     3721 gcctcgatct cgaaacccat ctgggtaagt gcaaaaacga tatctctcct gacatcttcc
     3781 gcggaatcgg ttggtgcaag gtcaaagtac cccccgtagt cctggtaatt ggtcgaaggc
     3841 ctgccgtcca ccatcttgaa gaggaagaat tcaagttctg gaccggtatt gaaggtaaaa
     3901 cccatctttt ttgcctgttc aatctggttt ttcaggacgt gacgcgggtc tccttcgaaa
     3961 ggcttgttcc cgtacgtgta aacatcacag atgaagcggg caacccttgc ttctgcaggt
     4021 ctccagggaa gtattgcgta tgtcgccgga tcgggtttca aaagcatgtc tgattcttcg
     4081 atccgtgcaa aaccctctat cgaggaaccg tcaaaccaga taccttcggt caatgccttt
     4141 tctgcctgct gcacgggtat tgcaacgttc ttgggcattc cctggatatc ggtgaactgg
     4201 aggcggagga acttgacatc gtcgttctca atcttctcca gcatctcgga tacggtgttc
     4261 ttccgcatat ggaaattaac ttctacctta tcagttatat atttaatgtt gaagggcgca
     4321 ctttaccggg aaagggagaa tgaccagggt gaccactctg ccctgacata ccgtggtcga
     4381 catgtgtggg ataattgctg ttattgaccg tgccgggtgc ccgatggacg gcacgaaaat
     4441 ccgctcggcc ctctccatga tggacgagcg ggggagcgga gaaggagcag gatatgcggt
     4501 gtacggggcc tttcccgaat ttgcagatta ttacgccatc catgtcttct tcgatgctgt
     4561 ccatgaatcg aaagctgcag tggacaggga actcgggaac tgggggacag ttgtgcacga
     4621 ggaggaagta ccgacttacg agaacaggaa tatccggaaa gtgcatactc cctggcgcta
     4681 ctttttcaaa ccggatccct ctctcatgcc aaggagcgaa accccggaag acgacatcgt
     4741 gatgcacctc gtgatgaaga tcaacacgac cattcccggc gccctggtat atgcatccgg
     4801 aaaaaacgtc gcgatattca aggcatcagg ctggccggaa gacgtcgccg acttctaccg
     4861 tatccaggac tacagcgggt acatctggct tgcgcacaac cggtacccga cgaacactcc
     4921 gggctggtgg ggaggtgcac accccttcaa cctcctcggg tggagcgttg tccacaacgg
     4981 cgagatcacg tcgtacggga caaacaggcg gttcatcgag agctatgggt acaggtgcac
     5041 gatgtacacg gatacggaag tcgttgccta cctcttcgac ctgctcgtgc gcaggcacgg
     5101 gctgagccct gaaatggccg tgaaagccct tgcacccccg ttctgggacg acattgaccg
     5161 gatgaacgaa aaagaacgaa cgttttacac ggcaatccgc cttgcatacg gttctgccat
     5221 gatgaacgga ccctttgcga tcgtcgttgc ccagcgggac ggcatcgtcg gtttcacgga
     5281 ccggatcaag ctccggccgc tcgtctgcgg gacagcgggt tcccgcctgt acatctcgag
     5341 cgaggaatct gccatccgca ccatggaaca cgatcccgaa gaagtgttca tgccgagagc
     5401 cggagagcct gtcatcggga ggctggggaa atgaccatcg ggagcgtacc ggtcaggttc
     5461 aggattacgg tggatggttc ccggtgcatg ctctgcggga ggtgcgttga aaactgcccc
     5521 tacgacgttt tcaggaagga aagcgacacg atccacgtga actcgcgcaa gtgcgtggcc
     5581 tgccacaggt gcatcgcgat gtgtccgcgg gatgcaatca gcataaagga acgtcccgtc
     5641 gattacagga gccaccccgt ctggacagag gaggcccggg aatcgatcta caaccaggcg
     5701 cggacgggga aaattatcct tgcgggaatg ggaaacgcaa aaccttatcc cgtcatattc
     5761 gacagcctgg tcctcgatgc ctgccaggta acgaacccga gcatcgaccc cctgcgcgaa
     5821 cccatggaac tgcggacata catcggcaag aagccgggga ggcttgaatt ccgggacgac
     5881 ggtgactgcc agtcccttgt cacgaccctc gcacccaacc tggaactcgc cactcccatc
     5941 atggtcggtc acatgagcta tggcgcgatc agtctcaacg cgcagaagag cattgcaatg
     6001 gctgtcaggg aatccgggac gttcatggga accggagaag gaggtctcca cccgtctctc
     6061 tatcccttcc aggaccacat gatcgtccag gtggcatcag ggaggttcgg cgtcgacatc
     6121 aactacctgg agaggggagc cgcaatagag ataaagatcg ggcagggtgc caagcccggt
     6181 atcgggggac accttccggg ggaaaaggta tgcgaggatg tctcctcgac gcggatgatt
     6241 ccggtcggga gcgatgccat cagcccggca ccccaccacg atatctacag catcgaagac
     6301 ctcaagcagc tcgtccgcag cttaaaagag gccacggaat ggaaaaaacc tgtattcgtg
     6361 aagattgcag ccgtccataa ctcagcggca atagctgccg gcatagcgcg gtcttcggca
     6421 gatgcggtgg tcatcgatgg tttccggggc gggaccgggg ccgccccccg tgtcttccgg
     6481 gaccatgtcg ggatccccat cgaggcagca gtcgccagtg tcgatgcaaa gctccgttcc
     6541 cagggaatac gcaacgaggt ctcgatcatc gcgagcgggg gtatcaggga gagtgctgat
     6601 gttgcaaagg tgattgcact gggagccgat gccgtctaca tcgggacggc ggccctcgtc
     6661 gcgatgggat gcagggtctg cggaacgtgc taccggggcc tgtgcccctg gggaatcgcc
     6721 acgcagcgcc cggatcttgt tgcccgtctc gacccggagg ttgcgtcacg gaacgtcgca
     6781 aacctcatcc atgcatggac cctcgagttg tccgaactga tgggggcagc aggcatcaac
     6841 agcatcgaga gcctgagggg gaacagggac cggctgaggg gatacctgct cgatgaatcg
     6901 atcatgcggg ttctcgatgt caaaccagtg ggggcatgaa gcgggcatga cgagagtgac
     6961 catcgatgct gccggtatgc actacacgcc gctcaaccgg cggatccgcg aggctatcgg
     7021 ggcgggggcg gatgaaatcg tcatcaccgg agtcatggga cagaggttca tcgcagacgg
     7081 tgtgagaggt cgtgggacga tcatcatcca tggaattccc gggggagacc tgggtatgtt
     7141 catgagcggc ccgacctgca tcgtttacgg caactgcgac cacgcacccg gaaacacgat
     7201 ggacagcggc acgatcatca tccacgggag cgcgggcgac gcggttgcac actcgatgcg
     7261 gggaggcagg gtctttgtca gggataacat cgggtacagg ggaggtatcc acatgaaaca
     7321 gtaccaggac aagtgcccgg tcctggtcat cgggggagaa ttccgctcgt tcctgggaga
     7381 atacatggcc ggcggactca tccttgccct cggcgacccc gggaaaaatt ccgggaggga
     7441 gagggggatc gggtccggga tccacggggg aaggataatc atcaggggcg gcccccttga
     7501 tgaccggtgc cttggagtgg gggcggctca aaggccgctt tcaggggagg gttaccggca
     7561 aatccagcca atcatcaggg agtttgcgga tgttttctcc cttgaccccg atcctcttct
     7621 ccgggacagg tacatcgaaa ttgtcccctc gagcagccgg ccatttgcaa acaagtatac
     7681 gtgggagtga ataccgtggt ggcagaacac agttacgttg atctccaaag agaggtctgg
     7741 gaaaggggca tctgcgcggg ttgcggggca tgcgtggctg tatgccctgc agatgcaatc
     7801 tgctttgacg agccgggggg tgccctccgg ccacgcaaca tcggttattg caagaaagag
     7861 aacgacgagg tgccctgcgg tgcctgctac gatgcatgcc cgcggacagg cccggcagtt
     7921 ccggaagaat gggagaatta cagggacata ctgtctgcac gggcgacgat ggagataccg
     7981 ggaaagcagg ccggcggcgc agtgactgca attctctccg catcgctgga gcagggactg
     8041 atagacggtg tcgtgactgt tacagcagac aggatgacat tactgccccg ctcggttgtc
     8101 cttacatcgg ccggaaaggt cagggagact gccgggagcc ggtataactg gtgggtcccc
     8161 ctcgtcgcag cgctcaagac tgctgtcatc gacatgaaac tcggcaaaat tgccatcgtg
     8221 ggagtcccgt gcgtgatcag ggcggttcac cagataagga cgagtgacaa tgatcttctc
     8281 aaaccctttg gttcacggat aaggctttcc atggggcttt tttgcaccga aacgttcgat
     8341 taccgcgtcc ttgtagggga gatcctcgga aaaaggcaca acataggaac aacagatata
     8401 gaccgcattg acgtgcgcgg gaaactcgag gttacaacga ggaaaaagga aaagattgct
     8461 ttccccatga gtgaactgaa agaggcaatc cgtcccggat gccatttttg cacggatttt
     8521 accgctgtcc attctgatat ctcggcagga gccgtgggaa gtcccccggg atacacgaca
     8581 ctgatcgtga ggaccgtgga aggtcaggtc ttcctcgacc aggcactggc tctgggcagt
     8641 ctcgagagag gtcccggggt caatctggaa gcagtcggga agctcgctgc agcaaagatc
     8701 agccgtgccc gaaagatttg aacccttttt taggaagttt taatgggaaa cagggaaaat
     8761 gtcctgatat tacaggtgga ttgggtacca tgaaatcatc gatcctgatt gccgggttcc
     8821 tcgtattcat gatcgcttct tgggcggtca gcgcggaaga agtccctttg ctcccggctg
     8881 aaaccggttt tccccagcca atgattccgc attcgtttta cggctccatt acagctgcag
     8941 gatcaccagt cccggcgggt gtgccggtcg aaatcgatgc cccgggaata aagaaaggga
     9001 tacccgaaaa ccccgtgtac tcgaacgagg ggggatatgg atcgccggat ccgttcagac
     9061 tccgcctcgc ggcccagggg acgatggaac caggcaccga acttgttttc tacgtgggtg
     9121 gtgtcagggc agaagtccgc ccgtcaggca cggaaaacga atggcagtct tcctttgcct
     9181 attcacccgg aggggtgacc agccttgatc tccgcgtttc cgtccccgtc accccggacc
     9241 ccgcttttcg catgacaccg gaagagacat cgtcgcaacc tgtaaaaaca cccccgcatg
     9301 gacagtcagg accctcgcag gaagtcatgc tcgggctcgt tgcaattctc gtcatcctcg
     9361 ccatcactgc atttttcctg gggaagaggg ctgaaaagaa ggagaaaaag tcgggagggg
     9421 aggaaggcac aattcagcag ggtggcagtc cccccggaga cgaaaaacag gagtgaaccc
     9481 tccctatcct attattttaa ataacagtac tccttctggt atggtgtaat cacggccgtg
     9541 cattgccgat tctccgggac atgaaaagac cggggaaaaa gaggaaatag cggaaaaaat
     9601 gaatacccaa agaacaggaa aagaggttac catggggcaa aacagaaaga tagttttttt
     9661 aatctgcatt atcggatgtg cactccttgc cttttcaccg gtgcttgcag gcgctggtga
     9721 ggaggaaaaa gagggagttt ttctcccgat tgagaatttt actgatcatt cacccaaagg
     9781 agaagccctg ctgcccgtgc aatttttggg tgctccggat gtgaacagtc ctttaaaaac
     9841 aatcaatatt tcccgggaac ttatgccggc tatttttgga aaggtgaatg caacagtata
     9901 ccgggaaaat actgtgtctg ccccgctttt ttccccggag gcacaacagg aatttgaaga
     9961 tatccgagag gccatcagga agtacaaggt ggcccccgca aacagggatt ttaaggatag
    10021 tattgcacgg ttaaagtcac tcaactcctc gggaaacagc gatggaaaag ggaacggtga
    10081 cgattcactc gggctcatac cctccccgat agatgttgtc ttcctcacgt ctgttggatc
    10141 ccgggactac gcgggaaata cggccggaag cgggacggcc ccactcctgc aggcgtcggg
    10201 atatacaagt gcttacgcac ctgccacgtt cgatctgcgc tcgacgggga agctgactcc
    10261 tgtcagggaa caggggcaat gcggtgcatg ctgggctttt tcaagttacg gatccctcga
    10321 gtccacgaac ctgcccggtt ccatgtggga tttttccgag aacaacatga aaaattccca
    10381 cggttttgac ctctccccct gccagggtgg aaattacctc atggctgccg cgtacctggc
    10441 gcggtgggcg ggacctgtca gcgagtcggc cgatccctac caggaatcag ggacaagacg
    10501 ggtccagaac gcgcctgtgc tcgagcatgt ccaggagatc tccttcctcc cgtcgaggca
    10561 gggggcgctt gacaatgctc acatcaagca ggccatcagg gagaatggtg cagtttattc
    10621 gtcgatccac tgggagaaat cgtattattc acccggcacg tattcctact actatcccgg
    10681 gtcttccatc cagaaccatg ccatcgatat cgtgggatgg gacgatacct acagccggtt
    10741 tcagttcgcc gtcacgcctc ccggtgacgg tgcgttcatc gtgaggaaca gctggggaga
    10801 agactggggc gagaggggat atttctacgt ttcctattat gatacgatta tcggaaagga
    10861 actgatccag ttcttcccgg aggaaacttc gaactatgac cggatgtaca gttatgaccc
    10921 cctgggctgg gtcacgagta tcggtgccgg agatgggaca ctctatgctg caaatgtctt
    10981 ttccgcatca ggaaatgaag aactccgtgc ggtcagtttc tatacgccgg tgaaagggac
    11041 atcgtacgaa atcgaggtca gcaaaaaccc ctccgccgga ccgagggggc aatattccca
    11101 gatggtcagt gccgggacat ttccctatgc cggttaccat accgttgccc tgaacaaccc
    11161 ggttatcctc gagaaggggg agaaattctc gatcatcatc aggctgacga cacccggata
    11221 cgggtatccc cttgcagtcg agtatcccat gaccgggtac tcgacacagg cggttgccca
    11281 ctccggggag agtttcataa gcacggatgg aaaaacatgg actgacctta cgcgtgtcgt
    11341 gcagaacggg aatgcctgca tcaaggcatt cacggtgaca aggaaatctg ccacaccgac
    11401 gccaacacca acgccaactc cccggcccac gccgaccggg acgactgttc ctgcaaccac
    11461 cccgactctc cccggtccgg gggacacgaa gtctccaacg gtgaccatcg tctccccaag
    11521 actcatgtct tctttttccc cgggagacac catacaggtt atctggtccg cgagggacag
    11581 cggggggata gcctccgtcc gggtcgagta ttcactggat ggagggagct cctggatact
    11641 cctccagact gcgacctctg aggcaggcac gtgttcctgg aaagttccgg acacgtgccc
    11701 cgcgaaggtg acattcaggg taaccgcggt tgacaacgca ggaaatgcgg cgtcggcatc
    11761 gcgggttgtc accgtgagga cgactaccgg aaaacccggg gcgggatttc ccgggataaa
    11821 aacgcccccg gttttccaga gggaaggaaa cggtgcggat atttccgggc aggctaatcc
    11881 ccaggcgatc tctgttgaaa ggaaagaata ctccatatcc ccgaaagtga gcgctcctgt
    11941 gcagtccatg gtcagcctga aaaaaggatc gcaagaagga acaaccagat cgcgcctttt
    12001 ctgatcatca acccctgtgg gcggacgaga gaaagactgc ctccttattt ttgacaccgg
    12061 ttgccggatg atcaccctaa taagagtaaa aagagaacat gggacagggt catgaaacgg
    12121 aaccagttgc ctgccagggg ctgtaccgta tgccatcagg gtgcaaaaat ggtccttttc
    12181 atcaccggga ggtgttcccg gacatgctgg tactgcccgc tctcggccca gaggaaaggc
    12241 agggacgatg tttacgccaa cgaaaaaaag gtacaaacgc ccggggaggc aatctctgtt
    12301 gcgcgcacga tggatgctct cggtaccggg gtaaccggcg gagaacccct cctcgtcccc
    12361 gggagggtcc gggagttctg catggaactc aaaaaggagt tcggggagga acaccacatt
    12421 catctctaca cggggctcgc tccgggaaag gatgaacttg gggcactctg tggactcgtg
    12481 gacgagatac gcatgcatcc tccgcaggaa gagtggcacc ggattggaga gagtgcattt
    12541 cttcattctg cctctctcgc ccgggaaatg ggcttttcgg cgggattcga ggtcccggcc
    12601 ctcccgggta tcgaagggct gcgtgatgcg ctttctgcac tcgacttcct caacatcaac
    12661 gagctcgagt ggggagagac caacgcggat gccatgcgga aaaggggaat ggaacctgcc
    12721 gatgaccttc acaatgcagt atcggggtgc cgtgactggg ctgccccgct cctcggtcac
    12781 ccgaaagtgc actggtgctc ctcccagttc aaggactccc accagctccg gaagaggctg
    12841 atccgggtcg cacgcaatac tgcccgcccc ttcgaccatg tcacggatga cggaacgatc
    12901 atctacggtg tcatcagggg tgggggcagc atccccgaga tcctttcccg gctcgacagg
    12961 gagatgtacg aggtcaggga tggggagatc gagaccctct ggtggatcgt ttctgaatat
    13021 tcagccgaaa ttggcggaga aaagtgcatc atcgagaggt acccggacag gggaatcatc
    13081 gtggaggtga ctcccgttcc atgatagaag atgccattct ctctttctac gagaggatcc
    13141 tccgcatgca gtgcaggcac ataccctcgc acattgccat catccaggac gggaaccgga
    13201 ggtttgcaag gacccgcaac atgccccgct cggaaggtca ccgggctgga gcaaacagga
    13261 cggaagagat gctttcgtgg gcacgagacc ttggaataaa acatatcaca ctgtattcct
    13321 tttcgacgga aaacttcaac cgggattcgg aggaagtcca ggacctcttt tgccttttca
    13381 aggataaact ctccagggtc atttcagatc cccgcgtgca cagggatgga atccgcgtcc
    13441 aggtggtggg ggacaggtcg ctccttcccc cggatctcca ggaggccatt gccagggccg
    13501 aggaagcaac aaagcactac gacaaatact ttttgaacgt ggcccttgct tacgggggga
    13561 ggaacgagat tgtcagggcg gcacagcgca tcatcggggg agtctcccgg ggggaggttt
    13621 ccctgcagga tatcaccccg gaattcgtgg aatcgcagct ccacgagggg cagaacatcc
    13681 cccctgtcga cctcatcatc cggacaggaa acgaatacag gacatcgaat ttcctgccgt
    13741 ggcttgcaaa cggtcatgag agcgcggttt atttctgtgc cccctactgg ccgcggttcc
    13801 gcaagatcga cctcctgcgc gcgatacgca cgtattcgca gcggatcgat gccatgggga
    13861 aggcgtcctg ttaaaaaacc tgttttgcat tggaacgcac agggggattt cccaaccgtg
    13921 tacccggctg catatccgga gaaccggttg ttatgacaat ggcaccgcca gttccattcg
    13981 taatacccgg aggcctgatg aaaatgacgt cgtttttcag aggccccgcc ccgtcacctg
    14041 tatcagaaac tttcatcccg aaagcgtgtt tgtacaatcc atcgctgtct ttgccgtctc
    14101 gtttgactgt ttttcgggca atcagaacgg gggccggatc aacgtccgaa ccggcgcatc
    14161 ctcgactggt aatcgcgcag tgccctgaga aaatcggttt tccggaagag tgaccagttc
    14221 acgtcggaga agaagagctc ggaatagacc gactgccaga tgagaaaatc cgtcaggtga
    14281 ctcccgcccg tcttgatgac gaggtcagga gtgtagcgga aagtgaggtg ttcctcgatc
    14341 gtgtgttcat tgacctggtc gggaggaatt cctttgcctg caatccggcg gatgcattcg
    14401 gtgatctcct cgcgcccgct cttcccgatt gcgacatgga cgttcatgcc cgagccggca
    14461 acttcggtct tatccccgta gtggagcgtc agccgtgcaa accgcgagat atcccggatg
    14521 ccgggaagca ggggtccgat ttcatccggg tcattcgtgc tgatatggaa cgtgactccc
    14581 cggatcacgc agttctcttc atctccccgc acctggtctc ttttttgacc gatcgtatcc
    14641 gaggtctcga tgcaccagcg gcaaacctcc gtgagctttt caggtgcttc cttctgttcc
    14701 tcccccgtga tcatgaagca tacatgggca gggagtatgc gaagcccgcc gatgaggtgc
    14761 ctctcgtaga gccagtgaat catgatgccc actccagaag gtccttttgt tccatgcagt
    14821 tgaggagagt cccgggagtc gcccatcccc gccggcagat accgataccg taccggatcc
    14881 agccgagttc cgaagcgtca tgggcatcgg tgccgagggc aaccttcacg ccacggtcaa
    14941 cagcctccct gatggcagtg tcatcaatgt ccatccggta gggggaagcg ttgcattcca
    15001 gtgccttccc gtgtgtggcc gccgcttcga tgaccctgtg gatgtcgatg gcaaagggct
    15061 cccgttcccc gatcagacgg ccggtcgggt gaccgaggat gtcgatatgt tcgttctcga
    15121 gagcagtgat cacccgccgg gtcatgacat cctggtcctg ggagaatccc gaatggaccg
    15181 atcccacgac gatgtcgagg tcagcaagga cgcgtgacgg caggccggga gtcccgtctg
    15241 caaggatgtc gacttctatc ccgtgcagaa cctggcagga ggaggatcgg ttggcaatct
    15301 cgatctcgtg tgcctgcttt cggattgctt cctcgtcgag tccatgggcg atcccgaggc
    15361 tcgcggaatg gtccgtgcag aggatatacg cgtagccgag actttcgccg gcccttgcca
    15421 acccctcaat atccatgtgc ccgtcgctcc acgtgctgtg gacgtggagg tctccccgga
    15481 tctccttctc atcgacgagc cgggggaggg tatgggagaa tgccgcctgt atctctcccc
    15541 agtcttcccg gagttcggga acgatgtagt ccatcccgag gaacgagaag atctcctctt
    15601 cccgggcaaa ggagtggacc ttgccccggc ccgcatcttc gatcccgtac tcgttgagct
    15661 tgaggcccct ttcgagcgcg atctcccgaa ggcggatgtt gaatgccttt gagcccgtga
    15721 ggtagaggag cattgccccg cacctgttcc gctcgatgaa ccgcacgtcg atgcgggttt
    15781 ttttgaaccg gaacgaggtc ttcttgtctc cctcgtcgat gacttcctct gcaatctgcc
    15841 ggatgcggga attgacggac gggggagaat ccacggtaac gatgtcgata tcgccaatgg
    15901 tgctcttttt ccggcggtaa ctcccggcca caacgaaagt gccttctgca aacacgcccc
    15961 tgataccttc tatcacctgg tcagcaaaaa gacgtgtcat ccttgcccgg ggctggcggt
    16021 agttttcaat tgcctcgagg aatgcctgtt ccttccgggg gccaaatccc ctcactgccc
    16081 gaatcctgtg accccgtgca gcacgttcga ggtcatcgat gctctggatg ccgagtttct
    16141 tccagagggt cttgatcgtc tttggtccga cgccatcgag ggcaagcatt tcgacgagag
    16201 aggcgggtac tgatgaccgg gcctcctcga gttcatggaa tgtcccggtc gcgatgatct
    16261 ccctgacctt ctttgcaata gcagtcccaa tcccgggtac cgcctcgagc tccccgggag
    16321 agagggttcc aacagggaca ccgagccgct caatgctctc tgccgcacgc cggtatgccc
    16381 ggaccttgaa ggggttctcg tcgaggatct cgaggatctc ccccatcagg ctgagctttt
    16441 ctgctacctc cctgtttgac atctccggat tcaggcaggc accccccggt tcaccagatc
    16501 atcatctctc caaatctaca tagtcattcg cttttgagag gaaaaacggg aaatcaattc
    16561 ttcggaaagg ggaaaaagag gggatcagat atgctggtcg atatccttga ggagttgctt
    16621 gatatcgatc cagatgatga gttcgttgac ggccttgtcg gtatccttct ccttgatgga
    16681 cttcttgatg atcccgagga tggacatatc ctccccgatc tcggatgcag acttcgtgtc
    16741 cacgtccttg aggtcgaacg tggagaccga gaggacatcg tcgaccatga tcccgatctt
    16801 ggacttggta ttcttctcgt cgaggacgat gatacggctg ttctcttcgg gctgggagga
    16861 ctcgtcggtg atatggagtc tctgtttgag gtcaacgatg gtggtgatct cgccgcggag
    16921 gtcgatgatc cccttgacgt agggaggggt gttgggcagt ttggtgatcg tcgtgtattc
    16981 gacgacctcc ttgacatcga agaggtcgat ggcgaaatgt tccttcccga ggaggaactc
    17041 gacgacctgg agggtaccgg aactccctcc ggcaccctgt acggcctttt tccccaccgg
    17101 tgcagctggt ttctccattg tttccccgct ctcttttgca gtcatggtcg ttaccccgcc
    17161 cgttaaatcc tgaacttgga gacttctgtc gagaccctga ccacgatgtt gttgacgttg
    17221 gcaatgacct ttgcgatctg gtcgatggca gctgccgtct cctcgctgac agccgcggaa
    17281 tcggttgcct ccttggcagt gttccggacg aggctgttca cctcgttgat gctggcggtg
    17341 acctcttcga ccgacgccgc ctgttcctcg gatgccgccg cgacttcggt cacgttccgg
    17401 ctgatctggt cgatggactc cacgatcctg ttgaagttct cgagtgtctc cttgagggca
    17461 acgctgcctt ccttgacctc gttgttcgag atggcaaccg tctcggcggc cgtctgggtc
    17521 tgtttctgga ggttgccgat catctcggcg atcttctctg cagagatgcg ggactcttcg
    17581 gccagggact tgacctcggt ggcgaccacg gcaaaccctc tgccggcatc gccggcacgg
    17641 gcggcctcga tcgcggcgtt gagtgcgagc aggttggtct ggttggcaag gtcggtgatc
    17701 aggttcacga tctcgccgat cttgtccatc tgggacttga tctcgaggat gatcgtgttg
    17761 acctcgttcg acgaccgggt gatgccgttc atgccaccct cggtcttctt ggcaagctcg
    17821 atacccttgc gggaatagtc gttggtctcc tggacgagct gggacacgga ctcggctttt
    17881 gccgcgacct gctggatggt cctggagagg tcttccatgg ccttcaagac ctcggtgatg
    17941 ccctggttgc tctgttcggc attcgtgctc acggcagccg cgttcttggc gacctgggca
    18001 gaccctgccg agacctcctc gatnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18121 nnnccgtcca tcacctgatt cccgagtgtc acaaggtcgc ccatccgccg ggctatcgac
    18181 ctgccgaaca tgagggagat gagggctccg actgcaatgc ttgccacgag gatgatgatg
    18241 atcgcgttcc ggatttcatc gatcggggcc atgaaatctg cgggatcgac acgcgaggcg
    18301 atgatccagt cgagggcagg gaagtacatg tagtaggcat cgatgttctt gccctcccag
    18361 acatactcga gctttgcggg tttatccctg accttatcct tgtttgcgat catcttctgg
    18421 atgaactcct ggtcggccat gttctggccc tgaagtgacg ggtggacgag aagtgtcccc
    18481 ttgctgtcca tgacatagac gtacccgctc tggccaagtt tcacgccgag gatctccttc
    18541 ttgaggcccc cgtacacgct gtcttcggga accccgacaa agaggatacc gatgatctcg
    18601 ccgctgctgc tcttgatagg ttcataagca gtgatgtacg tctttcccac gacgtcggcg
    18661 gtaccgtaat atgtctggcc tttcacgata acagcgtcat agacagcatc agagacgggc
    18721 gttccgattg ctctctttcc atcggcaccc acgacgttgg tggaaatgcg gatcgcctgg
    18781 ccacctgtct tttggaagat cgtggctttc gatcccgtca tcctctcgat ctggtcgacg
    18841 atctcgaagt tatcgttgac aacgaactcc cggcttccct ggcccctgag aacgagcttt
    18901 ccaccgctga tctccggcgt tccgtagcca tagaaggtgg atcggagaac gtttaagtca
    18961 ccgttcactt tctgctgtgc gagatcgtaa gtgttcgctg tcatcttctg aatgtcactg
    19021 atctccgttg aaagaagagt atcaacctgt ccggagatcg cggtgcttga actggtatac
    19081 gcaacgaggc caagcaggag cgttggcacg gttaccagta ccaggcagat tatcaggacc
    19141 ttggtcccta tcttcatctg ggagaaccca cgcaatctga tcatacggta atgcctcact
    19201 ttccagagta acccggatta tagccttccc ctgtccggga cgttcactcg cggatgtaaa
    19261 ccccccctga aagaggcagt gaaaacatac ccggtgggat taatgcacaa tggattctca
    19321 atgtatataa acttatagcc caatgaacat caaatacaat ggttaatata gttatacatt
    19381 gatgatggta atagttgttc catgcaatgc atgcacgatt gcatgcactg gggtagagta
    19441 tggtagaaag gggggatacc gaccggataa aggagttgct gggacagcac agaaacgggc
    19501 tcaccatcga tgaagtctcc cgtcacctcg ggataaacag gagcacagca tcgaagtacc
    19561 tgaacctcct cgtctcgtca ggtgcggcta ccatcaggaa gcttggtcct gccaagctct
    19621 tttacctgaa agaacgtgtc ccggttaacc agctgctgaa ctgcacatac gacggtatca
    19681 tcatcgttga cggcaaatac ggcatccatt acatcaatga tgtgatttcc actctttttg
    19741 gcatcgggaa ggaatcagtc atcggatcgg tcgctctcca gacacccctt gcacctctct
    19801 ttgaccccga aacccagcaa ttcatggggg aatccctcac gcgggaaggt cacgaaacgc
    19861 gggggacagt tcggattggt gaaaaaacct tcagtatcag gaagtgcatc atacccgtac
    19921 agttcgaatc ggggtcaacg ggatactgcc tcatatgcca tttcgatcag gggcaggtag
    19981 agcaaaaggc aagcggactg gaaaaggcat tgcctgacat ggcactgtat acccagtatt
    20041 accagctcga tgcactcatc aggcgatacg cgaagaacca ggtgaccact gctctcgaga
    20101 tcctgaaaaa aatggaaaag tccagggatc cggcacggtt ccgggaattt gcgggagagc
    20161 aggaagactt actcaaaggt atcctcgttc acctcatgat cttcgatgag ttcctcgaag
    20221 agactccacc gaggcaggaa tgggtccacc tcgaggaggt cacggggaac gcactctccc
    20281 ttgtccggct ctcccatgta aggttctttt ccgatatccg gggaatcgaa atctttgccg
    20341 acaggagttt ctg
//
LOCUS       DAOOJU010000027        19945 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2712_length_19945_cov_15.074711, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000027 DAOOJU010000000
VERSION     DAOOJU010000027.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 19945)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19945)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19945
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2712_length_19945_cov_15.074711"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            352..1215
                     /locus_tag="PK679_07145"
     CDS             352..1215
                     /locus_tag="PK679_07145"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55768.1"
                     /translation="MRSGQTVSGNGRIGIFIAVAATLVVLAAPVFADTPAEIAQGLMR
                     RADDLVLQGQYTEALDLYREAIDLDPYSSQIWNRLGITQMKVGRFPDAVESFQKALDI
                     DPYYTAAWKNKGNALQAQEQYQAAIDSYDRALAIYGSDLYTLYEKGVCLQKMGRSDKA
                     MEIYNEVVRLAEKEMRRNPNEARYNAQLWTTKGDALSHLGRYQEALEAYQEAVRINPK
                     MENAIAGLQRVNETLYRARSSPELLRTAVPPQTTAPRKTATPLAIPIPLLSLGIAALV
                     LAATVSRKGNR"
     gene            1234..2367
                     /locus_tag="PK679_07150"
     CDS             1234..2367
                     /locus_tag="PK679_07150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04084 family radical SAM/SPASM
                     domain-containing protein"
                     /protein_id="HPC55769.1"
                     /translation="MGMVFFHLILTDDCNLCCSYCRGRVLEGDAAWPGGRDVEIDWDL
                     PSDLSFDLQDLYSFLAKDPSACLTFYGGEPLLRIPLIEEIMDHLPAGRFMLQTNGLLL
                     SRLPAPYRNRFETILVSLDGTEELTDRHRGKGTYRRVMENVEDLARGGFCGELIARMT
                     VGEDTDIREAVRALAENPAYPFRSIHWQLDADFSGDGAMRTFCEWARTSYNPGIRRLV
                     RDWVEIMEAGEGVRRWYPFLQPMQDLLDGRASPLRCGSGHANYTIMTDGHIGPCPVMV
                     GMKEFYVGHIATADPLGLPRVAVDSACSSCHLLWFCGGRCLYSQVMRPWPEEMRRVVC
                     QTVENLHDCLLEVLPRVRECIRSGLIRKDDFSHTRYNGCEIIP"
     gene            complement(2384..2863)
                     /gene="rlmH"
                     /locus_tag="PK679_07155"
     CDS             complement(2384..2863)
                     /gene="rlmH"
                     /locus_tag="PK679_07155"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: protein motif:HMM:NF000985.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HPC55770.1"
                     /translation="MQVRLIGVGRVKENYLREGIRDYCTRIMPYMRVELRDIPDERIP
                     ERMGEREREDLLAREGARILAATKGTAIRIVCAVDGEPWSSEDLADMLKKWELAGQSR
                     VAFIIGGPLGLARPVLSAATHVLSLSRMTFPHQLARLILLEQIFRACRINSGEAYHK"
     gene            3185..3670
                     /locus_tag="PK679_07160"
     CDS             3185..3670
                     /locus_tag="PK679_07160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HPC55771.1"
                     /translation="MALRSLNLPGIGTKYELETEKKDIIAIFFLKSGNIQMYTLPHDS
                     STPCVAELTPPEARRIGAILSGAIMEADKESVEIAFSALSDLRISVHTYIIGKHCAGK
                     SLEELQIRARTGATVIAVSRGGRNIINPPPGFTFEEGDAIVAIGEADQLRQLEQVILV
                     T"
     gene            3670..4806
                     /locus_tag="PK679_07165"
     CDS             3670..4806
                     /locus_tag="PK679_07165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HPC55772.1"
                     /translation="MEGVVLALFVCLVLALITKKLALPSIPFYIIAGLLIGKSGLGLV
                     GVDGVAQFLTHLGLLFLLFFLGLEIKPDRIWSNHRAIAQSGLLDLHINVIIGFVAAYA
                     LGFSFADALVVAAAFFISSTAMAVTSLVENRKLLMREAETIVWLMVFEDIVVILVLAF
                     FGSSGEHPLIVLAKTVSLLLALILITQTGRDYITSILKRDDELPVLLTFSAVLGIAAL
                     ASAWGIPESFMVIAFGTILGTIDPVSFEVHSRPFKDVFLVVFFVFFGITTDIFAEGVS
                     VVAIAGVSIVAVFSKYLSGIAIGHFVHGNRNSGIEIWANTIGRGEFSIAIAALWGSGA
                     VSSTIATMVIVTSITGAFVAKYSNAIRNVLAWPREKNRGSPPPG"
     gene            complement(4848..6428)
                     /gene="sepS"
                     /locus_tag="PK679_07170"
     CDS             complement(4848..6428)
                     /gene="sepS"
                     /locus_tag="PK679_07170"
                     /EC_number="6.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043816 - phosphoserine-tRNA(Cys) ligase
                     activity [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-phosphoserine--tRNA ligase"
                     /protein_id="HPC55773.1"
                     /translation="MRFDPGAWKLRSREHFEKAWHEGPGVLTPPRAADRYPRLRYPAP
                     LPHPVFDMVHRLRETYLRLGFVETCNPIIVEEQDVYRQFGPEASAVLDRVFYLGGLDR
                     PNQGIGREELEGIASITGKEVTADEEAKLRQILQDYKRSVIDGDDLIHATSEALGIDD
                     GVTVEIYEKVFSAFRELTPRSSRSTLRSHMTSGWFLTLSALWERSPQPLKLFSVDRCF
                     RREQEEGPTRLMSYHSASCVVAGDDVTNEEGKAVAEALLSAFGFTDFRFRPDEKRSKY
                     YMPDTQTEVYARHPVHDWVEVATFGMYSPSALAEYGIGIPVMNLGLGVERLAMIATNA
                     KDIREMVFPQFHPRPLADLEIARGVTVRSEPVTVEGRVLCQAIARTAREHAAETGPCS
                     FVAFEGQLGAARIRVLVEEQEEGAKLLGPACGNEIFVYQGSILGVPDTPQWAVVRTEG
                     VSCGISYLDAVSMLAAARIEEGAACGKPVHVQVKMAKLPSDVNLRIADYVMRDITDRK
                     KKVDVRGPVFFAVRSELI"
     gene            complement(6425..7327)
                     /gene="twy1"
                     /locus_tag="PK679_07175"
     CDS             complement(6425..7327)
                     /gene="twy1"
                     /locus_tag="PK679_07175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-demethylwyosine synthase TYW1"
                     /protein_id="HPC55774.1"
                     /translation="MASTHSQPCDALRRQGYQFFREGSSAALKPCLWCKKALKGQEKC
                     YKHQFYGIESHRCVQMTPTLRCNQRCLFCWRSFEHTHPGGRDCTPAEIWERLPSLQKR
                     ALSGYKPSPYVTPERFAEALNPRHVAISLSGEPTLYPFLPELIGLFAENGLTTFLVSN
                     GTNPGVLSRCRPFQTYVSLTAPDRQTYLGLCRPEEDFWDRIQESLQLLGRRRSAVRIT
                     LVKGYNDFNPLSYARMVQDSGATFVEVKGYMFLGYSRKRLERENMPSFAHVKKFAEEI
                     ARGSGYRFRDENPASRVVCLERVE"
     gene            complement(7299..8963)
                     /gene="argS"
                     /locus_tag="PK679_07180"
     CDS             complement(7299..8963)
                     /gene="argS"
                     /locus_tag="PK679_07180"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011991281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HPC55775.1"
                     /translation="MLSRLYSTIESALRDACGQENVSLSDGGSHADLSSTVSFSLAKK
                     LRRSPAEIARDLAETLSRRQDLAGVRIEALGPYLNFHLGPELMEKALIEATQPGYGSF
                     PAREERVVLEHTSANPNGPLHVGHIRNTIIGDTLARCLRKAGYPLEVQYYVNDMGRQI
                     AIVVWGFQNIPDTPVPGEKGDHHVARIYIAANRELEKRPDAVAEVDLLMQRVESGDPQ
                     TVREFRSAVTECLDGFLVTLARLGAKHDRFVWESDFIRNGDTQRVLSKVSHMEECHED
                     GRLWLDLSAFGFEKEYVLRRSDGTSVYAARDLAYHIWKARNFDRVIDVLGADHKLIGA
                     QLATTLRLLGERPPEIVHFEFVSLPEGSMSTRAGKFVSADELLDEVTRRAYGEVTSRR
                     PELPEAQRHDIARSVALAAVRYDIVKISPDKSTVFDWKEALDFERQSGPYIQYAHARA
                     CSILEKAGTFATAYAPEDPHEHALVRHITRFPLVMENVVRDLKPHLLAAYARELADLF
                     NTFYHFVPVLKSEGVLRNSRLTLVLATRNTLAEALQALGIDPLTTM"
     gene            complement(8968..10242)
                     /gene="prf1"
                     /locus_tag="PK679_07185"
     CDS             complement(8968..10242)
                     /gene="prf1"
                     /locus_tag="PK679_07185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor aRF-1"
                     /protein_id="HPC55776.1"
                     /translation="MTETQEMDEGRRKYEFKKTLEKLQSKQGSGTELISLYVPPDKQI
                     HDVVAQLRDEFGQCANIKSKQTRTNVQSAISSILARLKYYKTPPPNGMAIFCGTIQLQ
                     GDRTDLECTIIEPPEPLNLYMYRCSSVFELEPLQQMLEEKNVYGLLVLDRREAYWGFL
                     RGNRIEPVGGVTSTVPGKQRKGGQSSVRFQRLREIAIHEFYTKIGERASAIFLAEKDF
                     FERFRGVLIGGPSPTKEEFEAGQYLHHEIQKRIIGLFDVAYTNESGLAELVDAARDAL
                     KGVEVIKEKELMNRFLKELVKENGLAAYGEESVRKNLATGSVDTLLLSASLRKSRVKV
                     RCQACGHAEERTVQLEPGKTIADILSSQTCRACGGPLIVDEETDIIEELTRLADQTST
                     RVQIISDDFEEGSMLYSAFGGIAAILRYRTGY"
     gene            complement(10280..11161)
                     /locus_tag="PK679_07190"
     CDS             complement(10280..11161)
                     /locus_tag="PK679_07190"
                     /inference="COORDINATES: protein motif:HMM:NF023568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HPC55777.1"
                     /translation="MRSFAVLSCLCLAALLIAGCSENRSGPGEGFSVDESGNLTLRCP
                     SCTFNETLMERSGNVSFYRVIFACRQGDVYALAAVPPAPVAGFVVAPGAGVKKEGYLP
                     VARQYAENGYAFLVLDVRGNGGETPGYPLDLARDFEKFRAGAWPQYYLSVCDMSSARR
                     YLQERYPIPVYAMGESNGGRYTAIAAETDPAFAGFIGISTSGFSGSGNAYTGDARRFL
                     LSVDPVTRADLLSSRTSWIFHAPADPVIPFSYGEELFAALPEPKVFFPFNGTHGSNAA
                     VHEMIMGKCAQIYGTAG"
     gene            complement(11158..11667)
                     /locus_tag="PK679_07195"
     CDS             complement(11158..11667)
                     /locus_tag="PK679_07195"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HPC55778.1"
                     /translation="MTEIYRGKRLAVERREYVLPNGKRVEKVSVHPGNAVAMLPFFGD
                     GSCCLIRQFRFVVGTYILEAPAGTLEPGEDPLEAARRELIEETGFDAETFIPRGWIYT
                     TPGFSDEVIFLYEARGLFPSSIHEKDEDEVIETVRVRTGDLPAMVRDGRISDAKTISL
                     VCRCMGQER"
     gene            complement(11664..12335)
                     /gene="queC"
                     /locus_tag="PK679_07200"
     CDS             complement(11664..12335)
                     /gene="queC"
                     /locus_tag="PK679_07200"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HPC55779.1"
                     /translation="MKAVCLLSGGMDSSTLAYLARDRGYSVLALHLNYGQRTEEKERA
                     SARTIARLLGAAEFLEIDLSYFSVFGSSSLTDRTIPVAPYRPEAEDIPNTYVPFRNAN
                     LLSIATSYAESRNADAIFIGVQSQDYSGYPDCRPAFIEAFQKVIETGTRSGSRIRLMT
                     PFISMSKKEILSLGLSLGVPYEHTWSCYQEKEVACGVCGACHFRRAAFDALGVKDPIP
                     YRNGT"
     gene            complement(12340..12948)
                     /locus_tag="PK679_07205"
     CDS             complement(12340..12948)
                     /locus_tag="PK679_07205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC55780.1"
                     /translation="MMVNEIFRSIQGEGINQGRPCTFIRFAGCNLDCSWCDTRRARSG
                     GREMDRDAILGRVRELGGRYVCITGGEPLMQGPPLLSLVQDLFSAGYAIDIETNGTLD
                     FSPFQPYAGICMDVKCPSSGEKSNLALLPLLSDRDAVKFVVSDLKDCEYAAGVMQTVP
                     HGTQVFFSPVGGTDPLVVARFLIREDLPARLQLQLHKVIGVS"
     gene            complement(12935..13348)
                     /locus_tag="PK679_07210"
     CDS             complement(12935..13348)
                     /locus_tag="PK679_07210"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070497 -
                     6-carboxy-5,6,7,8-tetrahydropterin synthase activity
                     [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="HPC55781.1"
                     /translation="MIFRIFREVQFDASHRLLHYHGKCNRLHGHRWKVEVWMEGQADE
                     RTGIVVDFNTIKEVICGFDHQVILNSEDPMADAIRTFHPVITTQGDPTSENLASLCAA
                     MIREESTRQGIDARVLRVRVWESPACYAEVTYDGE"
     gene            13517..13945
                     /locus_tag="PK679_07215"
     CDS             13517..13945
                     /locus_tag="PK679_07215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HPC55782.1"
                     /translation="MGKGKFAARKLIKDAKKFRWSDPKFVRSHGGVNIKSDPLEGAPQ
                     ARGIVLEKIGVEAKQPNSAIRKCVRVQLIKNGRQVTAFAVGDGAINFIDEHDEVEIEG
                     IGGRLGRSMGDIPGVRYVVTKVNNVSLHEMVIGRKEKPRR"
     gene            13954..14535
                     /locus_tag="PK679_07220"
     CDS             13954..14535
                     /locus_tag="PK679_07220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012616982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HPC55783.1"
                     /translation="MTETEPATRLLFNRWDLGEVQVTDPSLVKYISLNPVIVPHTTGK
                     FTRQEFNKANMLIVERLINRLMQSEMNTGNKQLATRIVRDAFDIIYKKTKKNPVQVLV
                     EAIANTGPREETVRLKYGGINVPKSVDTAPLRRVNTALFFISEAVYKAAHKSRKPVAQ
                     CLADELIAASKGDVKAYSVNKKEERERIAKSAR"
     gene            14564..16756
                     /locus_tag="PK679_07225"
     CDS             14564..16756
                     /locus_tag="PK679_07225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor EF-2"
                     /protein_id="HPC55784.1"
                     /translation="MARGRKSIEKVTELMSNPAHIRNIGIVAHIDHGKTTLSDNLLAG
                     AGIISEELAGKQLFMDSDEEEQARGITIDASNVSMVHEYEGQEYLINMIDTPGHVDFG
                     GDVTRAMRAVDGAVVLVDAVEGTMPQTETVLRQALKEGVRPVLFINKVDRLINELKVD
                     EMEMQIRLGRVIDKVNKLIKGMNEEAYKAGWKLDAAQGTVAFGSALYNWAVSVPFMKK
                     SGVSFKEVYEKCRSGSMKELAKKSPLCDVVLDMVVRHLPNPLEAQKRRIRVIWHGDPE
                     TPEGKAMLNCDPNGPATLMITDISFDPHAGEVATGRLFSGKIRRGTEMYVMGTAKKVN
                     RLQQVGIFMGPTRVEVEEITAGNIAAVTGLKDAIVGSTVTTLQDMTPFESLKHYSEPV
                     MTVAVEAKNMKDLPKLVEVLRQVAKEDPTLQVTINEETGEHLISGMGELHLEIITGRI
                     KRDKGVEIVTSEPIVVYRETVTQKAGPVEGKSPNRHNRFYIEVEPLPDAIVDLIKEGK
                     VSMNQMALERRDVLIAAGMDKEEAKNVKDIYGNNMFIDMTKGIQYLNETMELIIEGIH
                     EALDGGPLADEKVQNLKLRLVDVKLHEDAIHRGPAQVIPAVRAAVKAAMLMAGDTLLE
                     PVQKIQITVPTEQMGNATAQIQGRRGQVYDIQSEGDTVTVVGKAPVAELFGFAGDIRS
                     ATEGRAMWSTEFAGFELVPANMLKEVVSGIRKRKGLKEQIPTPADYLA"
     gene            complement(16908..17402)
                     /locus_tag="PK679_07230"
     CDS             complement(16908..17402)
                     /locus_tag="PK679_07230"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0016018 - cyclosporin A binding [Evidence
                     IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HPC55785.1"
                     /translation="MTTQATQGTPAPDQKVVLETTLGRIEIELFPDMPVTAGNFASLV
                     RKGFYNGTIFHRVIDGFMIQGGDPTGTGRGGPGYMIRDEFAPGRKNDRGTIAMANAGP
                     NTGGSQFFINLVDNHYLDGRHPVFGRVTAGMDVVDRIAKQKTDRNDRPLQPVTIIRAK
                     IAGD"
     gene            17530..18018
                     /locus_tag="PK679_07235"
     CDS             17530..18018
                     /locus_tag="PK679_07235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HPC55786.1"
                     /translation="MAGGKIKVVVFGAYNAGKSTLIQTLDPASRHVEAHTGEGDTTVA
                     LDYGRVDIHALQVYLFGTPGQDRFEFVRQIIARGMDAAILVVDSSVPPDEFTLHLFSA
                     LVDQKIPLAVMLNKCDLPGARPRDLEDTFKNALVFPVCAQDRGSVSAALTKFVESFIR
                     DL"
     gene            complement(18042..18524)
                     /locus_tag="PK679_07240"
     CDS             complement(18042..18524)
                     /locus_tag="PK679_07240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2124 domain-containing protein"
                     /protein_id="HPC55787.1"
                     /translation="MAEKEVFQGVPGMLRPFREFMEKKGFKRGDQVVYYGCPGTCTPF
                     VELLGFAIRSLELDQVFVPYVDESKARKVTLVPDVGMQASGAATVRNPAAVVVMGGLS
                     MPNVPVTLEQVTGAIGKYQGAAKVGVCFMNMFEKAGWTKEIHFDLLIDATINPVTVWK
                     "
     gene            18609..19175
                     /locus_tag="PK679_07245"
     CDS             18609..19175
                     /locus_tag="PK679_07245"
                     /inference="COORDINATES: protein motif:HMM:NF024135.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HPC55788.1"
                     /translation="MVTKVRQAGVRDVAGGKITGVPRTIMVGYATRYGSTAEIADIIA
                     EELRALGYIVDCVPLQKARSGPEGYDAAVLGSPLYMGKWLAEAREYISRERVALGKIP
                     VAVFSVGYTFRDQSPPVIQAGCDALSDVTGFIPVRDHAFFPGKVDMEKVSAADRAILS
                     LAKVTPGDFRNEDMVRAYARRLPQILGL"
     gene            complement(19249..19860)
                     /locus_tag="PK679_07250"
     CDS             complement(19249..19860)
                     /locus_tag="PK679_07250"
                     /inference="COORDINATES: protein motif:HMM:NF020950.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease inhibitor I42 family protein"
                     /protein_id="HPC55789.1"
                     /translation="MNRSMLLIAPVAIISVCLVLSSGCLQEQGTGKEPVTTGPVFGPQ
                     DNGKNVSIPAGTGFTVRLPENPTTGYMWNLTPPQGLAIDKDVFIAPDTKLVGAGGTRE
                     WVFSSKEKGLTLVHAEYRRPWVPAGTIVFVPLEGGFFGIAGDDGKNYLSLAISEEFRI
                     DGLRVAFEAEEAPDTATIQMWGTPVNVTFMEAVETYDLHVTLT"
BASE COUNT         4143 a         5803 c         5997 g         4002 t
ORIGIN      
        1 tgacgtcgcc ttcacacggc ggaggtcagg agttcgaatc tcctcgagcc cactaccgtt
       61 cagatctccg ctggtgacag gagagagtcc gcgttttata atgtcacgat gatgtgtgtc
      121 cccccaatac cctgcgcggg atttttccct cccatgaacc agcctgcctc tgccagagta
      181 attctatgcc cccaagtcca atctcccgag tgatttcagg gcggagggga atgacatatg
      241 cagggtgagg attcctgcac cattccggag ggggtcgaaa gacgctgcca cctttctggc
      301 agtcaaatca gcttttatat agtgccgggc atcaatgatt aaagaagtga tatgaggagt
      361 ggacaaaccg tatcggggaa tggcaggatc gggatcttca ttgcagtagc ggcaactctt
      421 gtcgttctgg cagcccccgt gtttgccgac accccggccg agattgccca gggcctcatg
      481 agaagggcag atgacctcgt gttgcagggg cagtatacgg aggccctcga tctctacagg
      541 gaggcaatcg atcttgaccc ctacagcagc cagatatgga accggcttgg gatcacgcag
      601 atgaaggtcg gcaggttccc cgacgcggtc gagtccttcc agaaagcact cgatatcgac
      661 ccctactaca cggcggcctg gaagaacaag ggcaacgctc tccaggcgca ggagcagtac
      721 caggcggcta tcgattcgta tgacagggcc cttgccatct acggcagcga tttgtacact
      781 ctctacgaaa agggggtctg cctccagaag atgggacggt ccgacaaggc aatggagatc
      841 tataacgagg tcgtccggct tgcagaaaag gagatgaggc gcaaccccaa cgaggcacgg
      901 tacaacgcac agctctggac aacgaaggga gatgcccttt cccacctcgg ccggtaccag
      961 gaagcgctcg aggcatacca ggaagcggtc cggattaacc cgaagatgga gaacgccata
     1021 gccgggttac agcgggtcaa cgagacgctc tacagggcac ggagctcccc ggaactcctc
     1081 cggacagcgg tcccgccgca gacgactgca ccaaggaaga cagcaacacc ccttgccata
     1141 cccattcccc tcttatcact gggcattgct gcacttgttc tcgcggccac ggtatcccgg
     1201 aaaggaaacc gataagagcc ctgccgtttt ccgatgggaa tggtcttttt tcacctcatc
     1261 ctcaccgatg actgcaacct gtgctgcagt tactgcaggg gaagggtcct tgaaggggat
     1321 gcagcgtggc cgggtggccg tgacgtggag attgactggg atcttccgtc cgatctctct
     1381 ttcgatctgc aggacctcta ttccttcctc gcgaaagatc cgtcggcatg cctgacattc
     1441 tacgggggtg agccccttct ccgaatcccc ctcatcgagg agatcatgga ccatctccct
     1501 gcaggaaggt tcatgctcca gacaaacggc ctcctcctct cccgcctccc tgcaccctac
     1561 cggaacaggt tcgagaccat cctggtctcg ctcgatggca cggaggagct gaccgaccgg
     1621 cacaggggaa aggggacata ccgacgtgtc atggagaacg tggaggatct tgcccgggga
     1681 gggttttgcg gggaactcat tgcccggatg acagtcgggg aggatacgga catccgcgag
     1741 gcggtccggg cacttgcaga aaaccccgct tacccgttcc ggtccattca ctggcagctc
     1801 gacgcggatt tttcggggga tggcgcgatg cggacgttct gcgagtgggc ccgcaccagt
     1861 tataatccgg gtatccggag gcttgtccgg gactgggtcg agatcatgga agccggggaa
     1921 ggggtccgcc gctggtatcc cttcctccag cccatgcagg atctccttga tgggcgggcc
     1981 agtccactcc ggtgcggttc gggccatgcc aactatacca tcatgactga cggtcacatc
     2041 ggcccctgcc cggtcatggt ggggatgaag gagttctacg tcgggcacat cgcgactgcc
     2101 gaccccctcg gcctgccccg cgtcgcggtt gactccgcgt gttcgtcgtg tcatctcctc
     2161 tggttctgcg ggggaagatg tctctattca caggtgatgc ggccatggcc cgaagagatg
     2221 aggagggtcg tgtgccagac ggttgagaac ctgcacgatt gcctcctcga agtgctcccc
     2281 cgggtcaggg agtgcatccg gagcgggctg atcaggaagg atgacttttc ccacacgcgg
     2341 tacaacggat gcgagataat cccctgacct ccctccccct cccttattta tggtaggctt
     2401 cgccgctgtt tatccggcat gcacgaaaga tttgctcgag gaggatgagg cgggcgagct
     2461 ggtgcggaaa agtcatccgg gagagggaga gcacgtgggt cgcggcagac aggacagggc
     2521 gtgcaagccc gagaggtccg ccgataatga acgcgaccct tgactgcccg gccaattccc
     2581 actttttcag catgtctgca aggtcctcgc tgctccaggg ctccccgtcg accgcacaca
     2641 cgattcggat ggctgtacct ttggtggcag caaggatccg tgcaccctca cgggcgagga
     2701 gatcttcccg ttcccgctca cccatccttt ccggtattct ttcatcggga atatcacgca
     2761 gctcgacccg catgtagggc atgatccggg tacagtagtc ccgaatcccc tcccggaggt
     2821 aattctcttt cacccggccg acaccgataa ggcggacctg catcacccat ggtgtggtcc
     2881 ctgctggcat taataaatgg aggatgggcc gtggtatccg gacactttca ccctccacgg
     2941 caggagttta tacactggca tgcccgacat ctggatcgag gaggccggaa agaaaacgac
     3001 ctccctctgc aaccctccaa agagccacct tgattgggaa ggacccgcca actccccccc
     3061 ttttttccgg gtcctcactc ctttttttgc acctgcagcc atggttctgc acgggcgggc
     3121 tgtagcccgg ggccattctc cccgtctcct cattcttttt aagatccgcg ggagaaacgt
     3181 gtttatggca ctccgctctc tcaacctgcc ggggataggg acgaaatacg agctcgaaac
     3241 ggaaaagaag gatatcattg ccatcttctt tttgaaaagc gggaatatcc agatgtacac
     3301 actcccgcac gattcgtcaa caccgtgcgt cgccgaactg accccccctg aagcccgcag
     3361 gataggagca atcctgtcgg gggccatcat ggaagccgac aaggagagcg tggagatagc
     3421 attctcggca ctctctgacc tccgcatcag cgtgcacacc tacatcatcg gaaagcactg
     3481 cgcgggaaag agcctcgagg aactccagat cagggcccgg acgggtgcaa cggtgatcgc
     3541 ggtatcccgg ggagggcgaa acatcatcaa cccgccgccc ggtttcacgt tcgaggaagg
     3601 agacgcgatc gttgccatcg gagaggcaga tcagctgagg cagcttgagc aggttatcct
     3661 ggtgacctga tggaaggggt cgtccttgct ctctttgtct gcctggtgct cgccctgatc
     3721 accaagaaac tggcgctccc ctcgataccc ttctacatca tcgcagggct cctcataggg
     3781 aagagcgggc ttggcctcgt cggggtggac ggcgtcgccc agttcctcac ccatctcggc
     3841 ctcctcttcc tcctcttctt cctcgggctt gagatcaagc ctgacaggat atggagcaac
     3901 cacagggcca ttgcgcagag cgggctgctg gacctccaca tcaacgtcat catcgggttt
     3961 gtggcagcat atgcactggg cttttcgttt gcagacgccc ttgttgttgc cgctgcattc
     4021 ttcatcagca gcacggcaat ggcggtcacg tcacttgtcg agaacaggaa gctcctgatg
     4081 agggaggcag aaaccatcgt ctggctcatg gtctttgaag atatcgttgt catcctcgtc
     4141 ctcgcattct tcgggtcatc aggggaacac cccctcatcg tccttgcaaa gacggtgagt
     4201 ctcctgcttg cccttatact gatcacgcaa acaggcaggg actacatcac gtcgatcctg
     4261 aaacgggacg acgaacttcc cgtgctcctg acgttctccg cggtgctcgg catcgcggcc
     4321 ctggccagcg cgtgggggat ccccgagtct ttcatggtga ttgcgttcgg gaccatcctc
     4381 gggacgatcg accctgtctc attcgaggtc cactcgaggc ctttcaagga cgttttcctc
     4441 gtggtcttct tcgtcttctt cgggataaca accgatatct tcgccgaagg ggtctcggtg
     4501 gtggcgattg caggtgtgag catcgttgca gtgttctcca agtacctgtc cgggattgcc
     4561 atcgggcatt ttgtccatgg aaacaggaat tccgggatag agatatgggc aaataccatt
     4621 ggccggggcg agttctcgat agccatcgct gccctctggg ggtctggtgc agtttcgagt
     4681 actatagcca cgatggtcat cgtgacctcg atcacggggg catttgtcgc aaagtacagc
     4741 aacgcaatca gaaatgtact tgcatggccc cgggagaaaa acagggggtc tcccccgccc
     4801 ggataggagg cggatagggt ggggggttgg cggatagggg caggcaccta gatgagttcc
     4861 gatcgcaccg caaagaaaac gggtccgcgg acatccactt tcttcttcct gtcggtgata
     4921 tcccgcatca cgtagtcggc gatgcgcagg tttacgtcgc ttggaagttt tgccattttg
     4981 acctggacgt gaacaggttt tccgcaggcg gccccctcct cgatccgggc cgcagcaagc
     5041 atgctgacag cgtccaggta ggagataccg caggaaacac cctcggtccg gacaacagcc
     5101 cactgggggg tgtccggcac accgaggatg gacccctggt agacaaagat ctcgttgccg
     5161 catgcaggcc cgagaagctt tgccccttct tcctgttctt cgacgaggac acggatccgg
     5221 gcagcaccaa gctgcccctc aaatgcaacg aacgaacagg ggccggtctc tgccgcatgc
     5281 tcccgtgctg tccgggctat tgcctggcac aggaccctcc cttccaccgt gacaggttcg
     5341 ctgcgcaccg tgactccccg tgcaatctcg aggtccgcga gaggacgggg gtggaactgg
     5401 ggaaagacca tttcccggat atcctttgca tttgttgcaa tcatggcaag gcgttccacc
     5461 ccgagaccga ggttcatcac ggggatcccg ataccgtatt cggcaagggc ggaaggcgaa
     5521 tacatgccaa acgtcgccac ctcgacccag tcgtggacgg gatggcgtgc atagacctcg
     5581 gtctgggtgt cgggcatgta gtacttcgac cttttctcgt ccggccggaa ccggaagtcg
     5641 gtgaaaccga atgcagagag gagggcttca gcaacggctt ttccctcctc gtttgtgaca
     5701 tcgtccccgg ctacgacaca ggacgccgaa tgatagctca tcagccgggt cgggccctcc
     5761 tcctgctcgc gccggaaaca gcggtccacg gaaaagagtt tcaggggctg cgggcttctc
     5821 tcccagaggg cagagagggt gaggaaccat ccgctcgtca tgtggcttcg cagcgtggac
     5881 cgggaggacc ggggagtaag ctcacggaaa gccgagaaga ctttctcgta gatctcgacg
     5941 gtcacgccgt catcgatacc gagggcttcc gacgttgcat ggataaggtc atccccgtcg
     6001 atcacggacc tcttgtaatc ctggaggatc tggcggagtt ttgcctcctc atcagcggtg
     6061 acctcctttc ctgttatcga cgcgatgccc tcgagctcct ccctccctat cccctggttg
     6121 ggacgatcga gcccgccgag gtagaagacc cggtcaagga cggcactcgc ttcgggtccg
     6181 aactgcctgt acacgtcctg ctcctcgacg atgatggggt tgcaggtctc gacgaacccg
     6241 aggcggaggt aggtctcgcg caggcggtgg accatatcga agacgggatg cgggagagga
     6301 gcagggtagc ggagccgcgg gtaccgatca gctgcccgcg ggggtgtcag gacacccggg
     6361 ccctcatgcc aggccttctc gaagtgttcg cgggaccgta gcttccaggc tccgggatca
     6421 aacctcattc gacacgctcc aggcacacga cgcggctcgc agggttctcg tccctgaacc
     6481 ggtacccgga accacgggcg atttcttccg caaacttctt cacgtgggca aagctcggca
     6541 tgttctccct ttccaatctt tttctactgt atcccagaaa catatatccc ttcacctcca
     6601 caaacgtggc gccggaatcc tggaccatcc gggcgtacga gagcggattg aagtcgttgt
     6661 agcctttcac cagggtaatg cgcaccgcag acctccgtct tcccaggagc tggagactct
     6721 cctggatcct gtcccagaaa tcctcttccg gcctgcagag tccaaggtat gtctgccggt
     6781 ccggggcggt aagcgagacg tatgtctgga acggcctgca ccgcgagagg acaccggggt
     6841 tcgtcccgtt gctcacgaga aacgttgtga gaccattttc ggcaaagagg ccgatgagct
     6901 ccgggaggaa gggatagagg gtcggctccc ccgagagtga aatggcgaca tgccgcgggt
     6961 tcagtgcctc ggcgaaacgt tccggcgtga cgtagggtga cggcttgtaa cccgagagag
     7021 cccttttctg gagcgagggg aggcgctccc agatctcggc cggcgtgcag tctctcccgc
     7081 cgggatgggt atgctcaaaa gaccgccagc agaagaggca gcgctggtta caccgcagcg
     7141 taggggtcat ctggacgcag cggtggctct cgatcccgta gaactggtgc ttgtagcatt
     7201 tctcctgccc cttcaaagcc ttcttgcacc agaggcacgg tttgagggca gcggaagacc
     7261 cttccctgaa gaactggtaa ccctggcgcc gcagcgcatc acatggttgt gagtgggtcg
     7321 atgccaagtg cctgcaacgc ctccgcgagt gtgttccggg tagccaaaac gagcgtgagg
     7381 cgggagttcc ggaggactcc ttcgctcttt aagaccggga cgaaatggta gaacgtgttg
     7441 aagaggtctg cgagttcccg ggcatacgca gccaggaggt gtggtttgag gtcacgcacg
     7501 acgttttcca tcacgagcgg gaaccgcgtg atgtggcgga cgagggcgtg ctcgtggggg
     7561 tcttccggcg cataggcagt cgcgaatgtc ccggcttttt cgaggatgct gcatgcccgg
     7621 gcgtgggcgt actggatgta ggggccgctc tgccgctcga agtcaagcgc ctccttccag
     7681 tcaaagaccg tgctcttgtc gggggatatc ttcacgatgt cgtaccggac cgccgcaagg
     7741 gcgacggagc gtgctatgtc gtgcctttgt gcctcgggga gttcaggcct ccgggatgtt
     7801 acctccccgt aggccctgcg ggtgacctcg tccaggagct cgtcggctga gacgaacttg
     7861 cctgccctcg tactcatcga gccctccggg agggagacga actcgaagtg gacgatctcc
     7921 ggcgggcgct ccccgaggag gcggagtgtc gttgcgagct gtgcgccgat cagcttgtgg
     7981 tccgcaccca ggacgtcgat gacccgatcg aagttccgcg ctttccagat gtggtacgcg
     8041 aggtcccgcg ccgcatacac tgacgtcccg tcactcctgc gcagcacgta ctccttctcg
     8101 aaaccaaacg cggaaaggtc gagccagagc ctcccgtcct cgtggcactc ctccatgtgc
     8161 gataccttgg aaagaaccct ttgcgtatcg ccgttccgga tgaaatcgct ttcccagacg
     8221 aacctgtcgt gctttgcgcc caggcgggcg agcgtcacca aaaacccgtc caggcactcg
     8281 gtaacggctg accggaactc ccggacggtc tgcgggtcac cggactcgac acgctgcatc
     8341 aggaggtcca cctcggcaac ggcatcaggc ctcttttcaa gttccctgtt cgcagcgatg
     8401 tagatccggg cgacgtggtg atcccctttc tcgcccggca ccggggtatc cgggatgttt
     8461 tggaaccccc agaccacgat cgcgatctgg cggcccatgt cattgacgta atactggacc
     8521 tcgaggggat agcctgcttt ccggaggcac cgggcgagcg tgtccccgat gatcgtgttc
     8581 cggatgtggc ccacgtggag cggcccgttg ggattggcac tcgtgtgttc gaggacgaca
     8641 cgctcctccc gcgccgggaa tgacccgtac ccgggctgcg ttgcctcgat tagtgccttt
     8701 tccatgagtt ccgggccgag gtggaaattg aggtaggggc cgagtgcctc gatcctgacg
     8761 cccgcaagat cctgccggcg ggagagtgtt tctgccagat cccgtgcaat ttctgcaggg
     8821 gaccggcgga gcttctttgc aagggaaaac gaaacggtgc tggagaggtc tgcatggctg
     8881 ccgccgtccg acagggaaac gttctcctgg ccgcaagcgt cccgcagtgc actttctatc
     8941 gtggaataaa gccgggagag catcatatca gtatcccgtc ctgtacctca gaatggctgc
     9001 gataccgccg aatgccgaat acagcatcga tccctcctcg aagtcgtcag agatgatctg
     9061 cacccgcgtg ctggtctggt ctgcaagcct cgtcagctcc tcgatgatgt ctgtctcctc
     9121 gtccacgatg agcggtcccc cgcaggccct gcacgtctgg gacgagagga tgtcggcaat
     9181 ggttttgcct ggctcgagct ggaccgtccg ttcctctgca tggccgcatg cctggcagcg
     9241 gacttttacc cgcgatttgc gcagggatgc cgagaggagg agggtgtcga cggagcccgt
     9301 tgcaaggttc ttccgcacgc tctcttcacc gtacgcggca agaccgttct ctttgacgag
     9361 ttccttgagg aaccggttca tcagttcctt ctccttgatg acctcaaccc ccttgagcgc
     9421 atcgcgggcc gcgtccacca gttccgcaag gccgctctcg ttcgtgtagg cgacatcaaa
     9481 gagaccgatg atgcgcttct ggatctcgtg gtggaggtac tggcctgcct cgaactcctc
     9541 cttcgtcggg ctcgggcctc cgatcaggac accccggaaa cgttcgaaga agtccttttc
     9601 ggcgaggaag atcgcgcttg cacgttcccc gatcttcgtg taaaactcgt ggatggcgat
     9661 ctcgcgaagg cgctggaaac ggacgcttga ctgcccccct ttcctctgtt tccccggaac
     9721 cgtggaggtg actcctccga cgggctcgat gcggtttccc cgcaaaaaac cccagtaggc
     9781 ctcgcggcgg tccagcacga gaagcccgta cacgtttttc tcctcgagca tctgctggag
     9841 cggttcgagt tcaaagaccg agctgcagcg gtacatgtag aggttgagcg gctcgggggg
     9901 ctcgatgatg gtgcactcga ggtcggtccg gtccccctgc agctggattg taccgcagaa
     9961 gatggccatc ccgttgggag gaggtgtttt gtaatacttg agccgggcga ggatggaaga
    10021 gatggcgctc tggacgtttg tccgggtctg cttgctcttg atgtttgcgc actgcccgaa
    10081 ctcgtcgcgg agctgggcga ccacgtcatg gatctgcttg tcggggggaa catagaggga
    10141 aatgagctct gtcccgctcc cctgcttgga ctggagtttt tcaagagttt tcttgaactc
    10201 gtacttcctg cgcccctcgt ccatctcctg ggtctcggtc atcttaccca cttccccggt
    10261 tccaaagctt cactatattt caacccgctg tgccataaat ttgcgcacat ttacccatta
    10321 tcatctcgtg cacggcagcg tttgagccat gcgtcccgtt gaacgggaag aaaacctttg
    10381 gttccgggag ggccgcgaac aattcctcgc cataggagaa ggggatgacc gggtcggccg
    10441 gggcatggaa gatccaggac gtccgcgacg acagaagatc ggcccgggtg accgggtcga
    10501 cggagaggag gaacctgcgt gcatcccctg tatatgcatt gcccgacccg gagaacccgg
    10561 acgtcgagat cccgatgaag ccggcaaacg cagggtcggt ctcagccgca attgccgtgt
    10621 accttccccc gttgctctct cccatggcat acacaggaat gggataccgc tcctggagat
    10681 accggcgggc agacgacatg tcgcagacag acaggtagta ctggggccag gccccggccc
    10741 tgaacttctc aaagtcccgc gcaaggtcga gggggtaacc gggagtctcc cccccgttgc
    10801 cccgcacgtc gagaacgagg aacgcgtacc cgttttctgc gtactgccgg gccacgggga
    10861 ggtacccctc ctttttcaca ccggcgcccg gtgcaaccac aaaccctgcc accggcgcgg
    10921 gaggaacagc agccagggca tagacgtccc cctgcctgca cgcaaagatc acgcggtaga
    10981 acgatacgtt cccgctgcgc tccatcagag tctcgttaaa ggtacaggaa gggcaccgaa
    11041 gtgtcagatt tcccgattca tcaacggaaa aaccctctcc gggaccggac cggttctcgc
    11101 tgcacccggc gatgagcagg gcggcaaggc agaggcagga gaggactgcg aaagatctca
    11161 tctctcctgc cccatgcacc ggcagacgag gctgatagtc ttcgcgtcag agattcgtcc
    11221 gtcccggacc attgcaggaa ggtcgcccgt tctgaccctg acggtctcga tgacctcatc
    11281 ctcgtccttt tcgtggatgg acgatggaaa aagcccccgt gcctcgtaga ggaagattac
    11341 ctcgtctgaa aacccgggtg tcgtgtagat ccagccccgg ggaataaagg tctctgcatc
    11401 gaacccggtc tcctcgatca gttcccggcg ggcagcttcg aggggatctt caccgggttc
    11461 aagggttccg gcaggcgcct cgaggatata tgtaccgacg acgaaccgga actgccggat
    11521 gaggcagcat gacccgtccc cgaagaacgg gagcatcgcg acggcatttc cggggtgtac
    11581 agagactttt tcgacccgct ttccgttcgg gagcacgtat tcccttctct cgaccgccag
    11641 cctcttcccg cggtatatct cggtcatgtc ccgttcctgt agggtatggg gtccttgacc
    11701 ccgagggcgt caaaggcggc acggcggaag tggcatgccc cgcagacgcc gcaggcaacc
    11761 tctttttcct ggtagcagga ccaggtatgc tcgtacggga caccgaggga aaggccgagg
    11821 gagaggatct ccttcttgga catggagatg aagggagtca tgaggcggat acgggaaccg
    11881 ctccgtgtcc cggtctctat caccttctgg aatgcctcga tgaaagcagg cctgcagtcg
    11941 ggatacccgc tgtagtcctg cgactggaca ccgatgaaga tcgcgtccgc attgcgtgac
    12001 tcggcgtaac tcgtcgcgat ggagaggaga tttgcgttcc ggaacggaac ataggtgttg
    12061 gggatgtctt ctgcctccgg acgatagggt gccacaggga tggtgcgatc cgtgaggctg
    12121 cttgacccaa agacagaaaa gtacgacagg tctatctcca ggaactcggc agctccaagc
    12181 agccgggcaa tggtccttgc agaggcccgt tccttctcct cggtcctctg cccgtagttg
    12241 aggtggagtg caaggacgct gtagcccctg tcccgggcaa gataggcaag cgtcgaagag
    12301 tccatgccac cggagaggag gcagacggct ttcatgtccc taactcaccc cgatgacctt
    12361 gtggagctgg agctgcaggc gggcgggcag gtcttcccgg atgaggaaac gggccaccac
    12421 aagggggtct gtccccccga cgggcgagaa gaagacctgc gtgccgtggg gcacggtctg
    12481 catgactcct gcggcatact cgcaatcttt caggtcactg acaacgaact tgacggcatc
    12541 acggtcagag agcaggggca ggagtgcaag gttactcttc tctcctgacg acgggcactt
    12601 gacatccatg cagatccctg catagggttg gaacggggag aaatcaagtg tgccgtttgt
    12661 ctcgatatcg atcgcgtagc cggcagagaa aaggtcctgc acgagggaga gaaggggcgg
    12721 gccctgcatg aggggctctc cccccgtgat gcagacgtac ctgccgccca gttcgcgaac
    12781 ccgtccgagg atggcatccc ggtccatctc cctgcccccc gaccgtgccc tccgcgtgtc
    12841 acaccatgaa cagtcgaggt tgcacccggc aaacctgatg aaggtgcagg gcctcccctg
    12901 gttgatgccc tccccctgga tactccggaa gatctcattc accatcatac gtcacttcgg
    12961 catagcatgc gggtgattcc cagaccctga cccggaggac gcgtgcatca atgccctgtc
    13021 tcgtggactc ctcgcggatc attgcggcgc agagtgacgc aaggttctcg cttgtcgggt
    13081 ctccctgcgt ggtgatgacc gggtggaagg tcctgattgc atccgccatc gggtcttcgc
    13141 tgttcaggat gacctggtgg tcaaacccgc atatgacttc ctttatcgtg ttgaaatcca
    13201 caactattcc tgttctttcg tcggcctgtc cctccatcca tacctctacc ttccagcggt
    13261 gcccgtggag ccggttacac tttccgtggt aatggaggag cctgtggctt gcgtcgaact
    13321 gcacttccct gaaaatccgg aagatcattg ggagagtgtt ggagggaacg ggatataata
    13381 ttattagcaa tggtgtccaa caaagtaagg caatcgtgga caagtgcaaa tgtataaatc
    13441 gccaccgcgc gtttatatat accacacagg gtgaattctg ttcactttca gagaaaaaca
    13501 gaaatgaggg tatttcatgg gtaagggcaa atttgcagcg agaaaactca tcaaggacgc
    13561 aaagaagttc cggtggagcg accccaagtt tgtgcgcagc cacggcggag tcaacatcaa
    13621 gtcggacccg ctggaaggag caccgcaggc ccgcgggatc gtgctcgaaa agatcggtgt
    13681 tgaggcaaag cagccgaact ctgctatccg caagtgcgtg cgtgtccagc tcatcaagaa
    13741 cgggcggcag gtcaccgcgt ttgcggtcgg cgacggtgcg atcaacttca tcgacgagca
    13801 cgacgaggtc gagatcgagg ggatcggagg tcgtctgggc aggtcgatgg gagatatccc
    13861 gggtgtccgg tacgtcgtga caaaggtcaa caacgtctcg ctccacgaga tggtcatcgg
    13921 gcgtaaggag aagccacgca ggtgaggtag aaaatgacag agaccgaacc cgcaacacgc
    13981 ctcctcttca acaggtggga tctcggggaa gtccaggtga ccgacccgag cctcgtcaag
    14041 tacatcagcc tcaaccccgt gatcgtccct catacgacag gaaaattcac ccggcaggaa
    14101 ttcaataagg ccaatatgct catcgtggag cgcctcatca acaggctgat gcagtccgag
    14161 atgaataccg gcaacaagca gcttgccacc cggatagtgc gggatgcctt tgacatcatc
    14221 tacaagaaga ccaagaagaa cccggtccag gtcctcgtgg aggccattgc gaacacgggt
    14281 ccccgtgaag agacagtccg cctcaaatac ggcgggatca acgtccccaa gtccgttgat
    14341 actgcgcccc tgcggcgggt gaacacggcc ctcttcttca tctccgaggc agtgtacaag
    14401 gcagcgcaca agagcaggaa acctgttgcc cagtgccttg ctgacgagct gattgccgca
    14461 tcgaaagggg acgtgaaggc ttactccgtg aacaagaagg aagaacgcga gcggatcgca
    14521 aaatccgcca gataaaaacc gatttacttt tttgtggtga tttatggccc gaggcagaaa
    14581 atcaatcgag aaagtgaccg aactgatgag caacccggct catatccgga acatcggcat
    14641 cgttgcccac atcgaccatg gcaagaccac cctgtctgac aacctgctcg caggggccgg
    14701 gatcatctcg gaggaactcg cgggcaagca gctcttcatg gactccgacg aggaggagca
    14761 ggcccggggt atcacgatcg atgcaagcaa cgtctccatg gtccacgagt acgagggaca
    14821 ggaatacctg atcaacatga tcgacacccc gggacacgtg gacttcggcg gtgacgtgac
    14881 cagggcaatg cgggccgttg acggggcggt cgtgctcgtg gacgctgtcg agggcaccat
    14941 gccccagacc gagacggtgc tccggcaggc actcaaggag ggagtccgcc cggtcctctt
    15001 catcaacaag gtcgacaggc tcatcaacga gctcaaggtc gacgagatgg agatgcagat
    15061 acggctcggg cgtgtcatcg acaaggtcaa caagctgatc aagggcatga acgaggaggc
    15121 ctacaaggcc ggctggaaac tcgatgcggc gcagggcacc gttgcattcg gctctgccct
    15181 ctacaactgg gcggtctctg tccccttcat gaagaagagc ggggtctcgt tcaaggaggt
    15241 ttacgagaag tgccggagcg ggagcatgaa ggaactggca aagaaaagcc cgctctgcga
    15301 cgtggttctc gacatggtcg tcaggcacct gccgaacccg ctcgaggcac agaaacgcag
    15361 gatacgggta atctggcacg gtgaccccga gacgccggaa gggaaggcca tgctcaactg
    15421 cgaccccaac gggcctgcaa ccctgatgat cacggacatc tccttcgatc cccatgcggg
    15481 agaagttgcg acgggccggc tgttttccgg aaaaatccgc cgcgggacgg agatgtacgt
    15541 catggggacc gcaaagaagg tcaaccggct ccagcaggtc gggatcttca tgggaccgac
    15601 acgggtcgag gtggaggaga ttacagccgg caacatcgcg gccgtgacgg gactgaagga
    15661 tgcaatcgtt ggatcgaccg tgacgaccct gcaggacatg acgccgtttg agtcgctcaa
    15721 gcactacagc gagccggtca tgacagttgc cgtcgaggcc aagaacatga aggacctccc
    15781 gaaactggtc gaggtcctgc gacaggttgc aaaggaagac ccgacactcc aggttacaat
    15841 caacgaggag accggggaac acctcatctc cgggatgggc gagctgcatc tcgagatcat
    15901 cacagggcgg atcaagaggg acaagggtgt cgagatcgtc acgtccgagc ctatcgtcgt
    15961 gtacagggag accgtgacgc agaaggcagg acccgtggaa ggaaagtcac cgaaccggca
    16021 caacaggttc tatatcgagg tggagccgct ccccgatgcg atcgtcgacc tgatcaagga
    16081 ggggaaggtc tcgatgaacc agatggcact cgagcgccgt gatgtcctca tcgctgcggg
    16141 aatggacaag gaagaggcaa agaacgtcaa ggacatctac ggcaacaaca tgttcatcga
    16201 catgaccaag ggtatccagt acctgaacga gacgatggag ctgatcatcg agggtatcca
    16261 cgaggcactc gatggcgggc ctcttgccga cgagaaggtc cagaacctca agctccgcct
    16321 cgtcgacgtg aaactgcacg aggatgccat ccaccgcggc cccgcacagg ttatcccggc
    16381 agtccgcgcg gcagtcaagg cagcgatgct gatggcaggc gacaccctcc ttgagcccgt
    16441 ccagaagatc cagatcaccg tcccgactga acagatgggc aacgccactg cccagatcca
    16501 ggggcgccgg gggcaggtct acgatatcca gagcgagggt gacacggtga ccgtcgttgg
    16561 caaggcaccc gtcgccgagc tcttcggttt tgcaggggac atcaggtctg cgaccgaggg
    16621 gagggcgatg tggagcacgg agtttgcagg gtttgagctc gtgccggcca acatgctcaa
    16681 ggaagtcgtg tccggcatcc gcaagaggaa gggattgaag gaacagatcc cgacacctgc
    16741 agactacctg gcctgaaaaa ctaaaaaaaa actttttttc acggttttcc gatcaattgc
    16801 ggaacctgcc gttttttttg ttccaggtcg cctttttttg ggcgggttgc ccgtgggaaa
    16861 aagacgggca attcccggca caggggccgg agcagggaga agagccttta atcccctgcg
    16921 atttttgccc ggatgatcgt gaccggctgg agcggacggt cgttccggtc ggtcttttgc
    16981 tttgcaatcc ggtccacgac gtccattcct gcagtgaccc ttccgaagac cgggtggcgc
    17041 ccgtccaggt agtggttgtc caccaggttg atgaagaact ggcttccacc cgtgttcggg
    17101 cctgcgttgg ccatggcaat ggtcccgcgg tcgtttttcc tcccgggtgc aaattcgtcc
    17161 ctgatcatgt agcccggtcc accccgcccg gtcccggtgg gatctccccc ctgaatcatg
    17221 aaaccatcga tgaccctgtg gaagatggtc ccgttgtaaa agcctttccg gacaagcgat
    17281 gcgaagttcc ctgcggtgac gggcatatcc gggaagagct cgatctcgat tctcccaagg
    17341 gtcgtctcca atacaacttt ttggtcagga gcgggagtgc cctgtgtggc ctgagttgtc
    17401 atggggaata gtattgcccc gtacccacaa ggagtttgtg aaagaggtga aacttgggga
    17461 gatatagttt cgccaaaaaa tccggattaa tatcgaaacg gtaaaaaaag ccggaacaaa
    17521 gtacttgtaa tggctggcgg aaagatcaag gtcgttgttt tcggggcata caacgcagga
    17581 aagtcaacac tgatccagac acttgaccct gcctcccgtc acgtcgaggc acataccggg
    17641 gaaggggaca cgaccgttgc cctggactac gggcgagtcg acatccatgc actgcaggta
    17701 tatctctttg gaactcccgg tcaggatcgt ttcgagttcg tgcgccagat catcgcccgc
    17761 ggaatggatg cagccatcct cgttgtcgat tcaagtgtcc ctcccgacga gtttacgctg
    17821 cacctcttct ccgcgctcgt ggaccagaag ataccgcttg ccgtgatgct gaacaagtgt
    17881 gaccttcccg gcgcccgtcc ccgggatctc gaggatacgt tcaaaaatgc actggtattc
    17941 cctgtatgtg cgcaggacag gggatcggtc agcgcggccc tgacaaaatt cgtggaatct
    18001 tttatcaggg atctttaagg gaaaaaggga ggtattcccc ctcatttcca gacagtgaca
    18061 gggttgatgg tcgcatcgat gaggaggtcg aaatgaatct cctttgtcca ccctgccttc
    18121 tcgaacatgt tcatgaagca gacaccgacc tttgccgcac cctgatactt cccgatagca
    18181 ccggtaacct gttccagcgt tacagggacg ttgggcatcg agagtccccc catcaccacc
    18241 actgcagcgg ggttcctgac ggttgcagca ccggatgcct gcatccctac atccggaacg
    18301 agggtcactt tgcgcgcctt tgattcgtcg acgtacggga caaagacctg atcgagctca
    18361 aggctccgta tggcaaaccc aaggagttcc acgaacggtg tacaggttcc ggggcacccg
    18421 tagtaaacga cctggtcacc gcgtttgaag ccttttttct ccatgaactc cctgaatggc
    18481 cggagcattc ccggcacgcc ctggaagacc tctttctctg ccatctcaat tgtgctccta
    18541 tgagtaagaa taacctccgc ggtttatatg aatctatagg tacacaagaa gagaaggggg
    18601 ataaccggat ggtgacaaag gtcagacagg caggagtcag ggacgtggca ggcgggaaga
    18661 ttacgggagt gccgcggacc atcatggtcg ggtatgcgac caggtatggc tcgacagcgg
    18721 aaatagcaga cataatcgca gaggaactcc gggcccttgg gtatatcgtt gactgcgtgc
    18781 ccctgcagaa ggcccgttcc gggccggaag gctacgatgc cgcagtcctt ggcagcccgc
    18841 tctacatggg caagtggctg gcggaggccc gcgagtacat ctcccgggaa cgggtggctc
    18901 tcgggaagat ccctgttgct gtgttctcgg tcggctacac gttccgggac cagtcaccac
    18961 cggtgatcca ggctggatgc gacgcgctct ccgacgttac cggtttcatc ccggtcaggg
    19021 accatgcgtt ctttcccggg aaggtggata tggaaaaggt gagtgctgcg gaccgggcga
    19081 ttctctcgct ggcaaaggtg accccgggcg atttccgcaa cgaggacatg gtccgggcat
    19141 atgcccggcg actcccgcag atccttggtc tgtgaaactg cagggaaaag gaaagggcgg
    19201 ggattgaaaa atccctgccg gaccgtattc gggtttccca cgggttttct atgtcagtgt
    19261 gacatggagg tcgtacgtct ccacagcctc catgaatgtt acgttcaccg gagtgcccca
    19321 catctggatt gttgcggtgt ccggggcttc ctctgcctcg aaagccacgc gaagaccgtc
    19381 gatccggaac tcctcactga tagccaggga aaggtaattt ttgccatcgt cacctgcaat
    19441 cccgaagaac ccgccttcaa ggggtacgaa gacgatggtg ccggcaggaa cccacgggcg
    19501 cctgtactcg gcgtggacga gggtgaggcc cttttctttg gacgagaaaa cccactcccg
    19561 ggtcccgcct gccccgacga gcttcgtatc gggcgcaata aacacgtctt tgtcgatggc
    19621 aaggccctgc gggggggtca ggttccacat gtaaccggtt gtcggattct cgggcaggcg
    19681 cacggtaaac cctgttcccg ccgggatgga gacgttcttg ccgttgtctt ggggaccgaa
    19741 tacgggacct gtggtcacgg gttccttacc ggtgccctgt tcctggaggc atccggaaga
    19801 gaggacaagg catacggaga ttatcgccac gggggcgatg aggagcatgg aacggttcat
    19861 tgtctgattc accttcttgt atggaaagaa agagggcatg gccggatata cactttccca
    19921 tgattgcgaa ggaaatcgca gtcat
//
LOCUS       DAOOJU010000028        19755 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2739_length_19755_cov_15.187310, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000028 DAOOJU010000000
VERSION     DAOOJU010000028.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 19755)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19755)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19755
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2739_length_19755_cov_15.187310"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1141
                     /locus_tag="PK679_07255"
     CDS             <1..1141
                     /locus_tag="PK679_07255"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC55790.1"
                     /translation="PATTTAPASDLCSLCLESDPASALVTIDGIERGVTPICVPLAPG
                     THRITISKEGYVPWEGEITTGASQTLSLPVFSLRPVARFVVEAGCSPGGAVLPEGPVR
                     VPKGGTVEFLFVPETGYELVDVLVDGRSIGPHPRTRLEGISRNHTVRGVFSPVTPSSP
                     VAAILANSTDGVAPLAVQFQDVSEGDVANRSWDFGDGTSSTDPSPVHVFYEPGNYTVT
                     LGVCGRGGCNLSAPSCLIVVREGSTGGNGTSGESGGGGVTPGADDDNPPLIGGSTGFL
                     RVRCPVEGASVFIDGDYRGEIRNGTLDILIYLTGTPCRAVTVKAPGYLPATVPISRYP
                     DEGETVVIEVAPILIGPSPGVFEGQGRSSPLPGNVTPTIPSLSSG"
     gene            1200..1643
                     /locus_tag="PK679_07260"
     CDS             1200..1643
                     /locus_tag="PK679_07260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HPC55791.1"
                     /translation="MEPDGDDGLSPRKVSYLKFLRERGNAARTGEIAERFSVDPSTVT
                     RAVQELAAAGLVFHQPYGRVTLTEKGVARADFLVWRHRVLGLVLSHYGLAGEEACREA
                     ERFEAYVSAGAVRRICASLGHPTRGICGAICHDALCGAEKEEENF"
     gene            1716..2594
                     /locus_tag="PK679_07265"
     CDS             1716..2594
                     /locus_tag="PK679_07265"
                     /inference="COORDINATES: protein motif:HMM:NF013465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HPC55792.1"
                     /translation="MLVILVAISGCLSEGTDGRGTPHGKTAVVTILPQAEIVREIAGG
                     DWEVVVVVPPGVEPHTYEPTASQVARVSRADAYVRLGPDLMPFEDTLVQRITAREPGI
                     AIIDMSEGISLLYGDGKGDEGTTRSRTGADPHIWLSPANLRIMAENVARGLSELDPAH
                     AADYAARKNAYLGKIDSCTGAIRRNVSGLEGRSFLVFHPAFGYFARDFSLNQVAVGEG
                     GHEPGPAGLSRLVSLAREEGISVVFAEPQFSTRESEVIAREINGTVVLVDPLAPDVLE
                     NLVRISGAIRNSYGVG"
     gene            2591..3388
                     /locus_tag="PK679_07270"
     CDS             2591..3388
                     /locus_tag="PK679_07270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HPC55793.1"
                     /translation="MTRTGDPRMRPVIEVSDVSFGHNGKVILEHVSLKVRKGDFFALI
                     GPNGGGKTTLLKIILGLLVPSGGTVTVLGQPPGRARSRVGYVPQFRTYDFSYPITVRE
                     MVLSGRLSHARFPWARYTPADHEAADRILERLRMAPLAERPVSALSGGEQQRAILARA
                     LVGNPEVLILDEPTVYIDAPTEVHFYNILEDLRKDLTVLLVSHDIGVISRHVTRVACL
                     NRRLFTHDSPEITEDMIEAAYQCPVDLIAHGIPHRVLGDHPGEGGSR"
     gene            3388..4263
                     /locus_tag="PK679_07275"
     CDS             3388..4263
                     /locus_tag="PK679_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HPC55794.1"
                     /translation="MDAGILSFGFFQNAILAAVLASIACGIIGSLVVVKRMVTVSGGI
                     SHAAFGGVGLGYLFSIDPIVGAFFFSVGVALCIGIVKEKAGQEIDTLIGAVWAAGMAV
                     GIISVSLAEGYTPDLFSYLFGNILLVPQGDIILMAVFSACIVAIVALFYLPLQAVTFD
                     EEYARVMNLPVTALSLVLLVLTATCVIILIRLVGIILGIALLVLPAASVRGFTTRLPT
                     MMAASVVLALVLSLSGLFLSYAWDLPSGATIILLGAAVYAVSLVLSRFSPARRWGGGT
                     RSDRRLPQQEGPEGR"
     gene            complement(4184..5293)
                     /locus_tag="PK679_07280"
     CDS             complement(4184..5293)
                     /locus_tag="PK679_07280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HPC55795.1"
                     /translation="MKENLPLLAGAFSVMALSNAIVPVLPSFSTGAAAQGAIYSAYFL
                     GAFLLVLPAGYVSDRIGEVPLIRAGLVLTTLSGVLLALAGSPLLVFLARLVEGIGAGL
                     FVPASLAFLNARPDHDRMSGYFMGLLNLGLILGLLVTGWLVTGSPGSSRGGIIFFTWL
                     SVVPLVLAFATGRGQEMSHRVPAEPAQETKKRLVWAFRTYFWLWVSAVVLVGITGAVT
                     ALYPEFTDLPASSVSGKIALMNAATIASVIVTSRANLPPVRTIQLAAVAMAGGVALTF
                     YSMWGFLVIGWLAGMVMISQLSFLAAAGARQGVLMGLFNTASYGGMTAVPFIAGFVAE
                     TGGFPAAYTLTALLALLVAATVGRCACRLPTAGPG"
     gene            complement(5290..7179)
                     /locus_tag="PK679_07285"
     CDS             complement(5290..7179)
                     /locus_tag="PK679_07285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-CASP ribonuclease aCPSF1"
                     /protein_id="HPC55796.1"
                     /translation="MLIEERLKELKDKINEKVPAGITVSDVEFEGPELVIYTDDPKRF
                     ADQADLIKVLARDLRKRIVVRPNVLEDPEKAIRDIRAVVAENAGITDIFFDADTGEVL
                     IEAEKPGVVIGKNGATLREITRHIGWTPKVVRTPPIESSTVKQIRQYLRSVNEERKEF
                     LRAIGRRIHRDVIARDQWVRVTMLGCCREVGRAAFLLSTPESRVLIDCGEKPDNSAST
                     PYLYVPEIHPLSQLDAVVLTHAHLDHCALVPLLFKYGYDGPVYSTPPTRDLSAMLQLD
                     YLDVVSKEDRKIPYSSNEVKSYIKHSITLNYGSVTDIAPDIKLTFHNAGHILGSAIAH
                     FHIGDGLYNIAFTGDFNFSKSRLFNPATCNFPRLEALIMESTYGGSGDIQPTRAEAEE
                     KLYETVNNTIRRGGKVIIPAFAVGRSQEVMLALEEGMRRQKIPTVKIYLDGMIREATA
                     IHTTYPEYLNSELRTQIFKEDHNPFLADCFVPVDSSELREKVIMGDPCVIITTSGMLN
                     GGPVMEYLSNLASDEKNALVFVGYQAEGTLGRRIQKGWREVPIGRKGTIVINLEIVTI
                     DGFSGHSDRKQLMSFIAHVQPRPEKIFTVHGDENNTIDLASSIYKRYHIETHSPMNLE
                     TYRMV"
     gene            complement(7201..7842)
                     /gene="psmB"
                     /locus_tag="PK679_07290"
     CDS             complement(7201..7842)
                     /gene="psmB"
                     /locus_tag="PK679_07290"
                     /EC_number="3.4.25.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000502 - proteasome complex [Evidence
                     IEA];
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaeal proteasome endopeptidase complex
                     subunit beta"
                     /protein_id="HPC55797.1"
                     /translation="MNEQYREGMTGTTTVGLVLRDAVVLASEMRATMGYLIASKKAKK
                     IYQIADRIGMTTAGGVGDAQQIARLMTVECSLYQIRRGRPITIGAVATLLSNILNANR
                     YYPFYVQLLVGGVDEGGPKLYAVDALGGASREEEMVATGSGSPMAFGVLEDRYSKDLS
                     EDEAVALAVRAIRSAMKRDAGSGEGIHVVVITKEAYRELTESEIAGLSPVSPA"
     gene            complement(7934..8779)
                     /locus_tag="PK679_07295"
     CDS             complement(7934..8779)
                     /locus_tag="PK679_07295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HPC55798.1"
                     /translation="MKVSDFMTTDVVSVEIPGNRDDVLKILKRTGISGVPVLKDGKLV
                     GIITRKDLLRKAEETQLGLLMTHDPITISPDATIREAASLMIKHSIRRLPVIEDDDLV
                     GLISVADLVAALAQMKVRDEIKESYISQTFALWEETPLPLVGRIMEISGFDAIPILDE
                     ESILQGIISERDLIRHSSIEDTVEVSDFSNGTDDDEWTWESIRDMHTISYGISKIQLP
                     NRPVKTAMVRNVISVPLNAEVSECALKMKRARVDQLPVVNGDRKLVAMLFDRELIRAL
                     CKDRP"
     gene            complement(8776..9213)
                     /locus_tag="PK679_07300"
     CDS             complement(8776..9213)
                     /locus_tag="PK679_07300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HPC55799.1"
                     /translation="MFSDILVAVDGSNMGRRAFEVALDEARVWKAKVHVVYVVETGLF
                     SSLPMDSTWEIMFSMLEKEGQETLERAKEAAQKAGVALETHIRQGHAGNEIVRTAGEV
                     GADLIVVGSHGKSEVDRLLLGSVSSFVVSNSKVAVLVVRPSQK"
     gene            complement(9251..10300)
                     /locus_tag="PK679_07305"
     CDS             complement(9251..10300)
                     /locus_tag="PK679_07305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HPC55800.1"
                     /translation="MSGGELLVEGRALLGEDFEEAPVRVVVEGGTIAHIEELGGPGND
                     LPWIVPAFFNAHTHVGDSVALDIPLEGDLDALVRPPDGLKHRILRSVSRTELVRAMRL
                     TIGTMAHGGTAGFADFREGGRDGVSALLEAAEGISCRPVIFGREGGEMVAQGLGISSA
                     RDVGGSLDEMVSLARRIGKLVAFHAGERDPSDIGQALAYEPDLLVHCTHASKDQLRQI
                     ADAGIPVAVCPRANWRFRVTSSGMRPPVRELLSLGGTILLGTDNAMCVQPDMWREMEF
                     LSTVYRVSPREALRAATLGASLFMEPFYIREGNRAAFLVIDPRPSNLSLSRDIAAALV
                     NRAGPANIVRKVINL"
     gene            10347..10505
                     /locus_tag="PK679_07310"
     CDS             10347..10505
                     /locus_tag="PK679_07310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit Sec61beta"
                     /protein_id="HPC55801.1"
                     /translation="MAKKQGGRLISSAGLVNYYESEDKRAIHISPYSVIIVCAAIGVA
                     ILVLNIIY"
     gene            10733..10999
                     /locus_tag="PK679_07315"
     CDS             10733..10999
                     /locus_tag="PK679_07315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1922 domain-containing protein"
                     /protein_id="HPC55802.1"
                     /translation="MFLIIRCPGCRTFSYVDRFQQWKLCPVCGEAIEVAKAPAYIEVD
                     EYRVAERIVSQLEDYLHRNRKKDLSPEELAALREQYAEWLRSKA"
     gene            complement(11010..11159)
                     /locus_tag="PK679_07320"
     CDS             complement(11010..11159)
                     /locus_tag="PK679_07320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PriA"
                     /protein_id="HPC55803.1"
                     /translation="MVRHECGYEQEILCRRCGSTVVYNERTGLFCPRCRREITLVCPG
                     CGKKW"
     gene            complement(11343..13121)
                     /locus_tag="PK679_07325"
     CDS             complement(11343..13121)
                     /locus_tag="PK679_07325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis/translation initiation
                     ATPase RLI"
                     /protein_id="HPC55804.1"
                     /translation="MRIAVVHRDRCHPRKCGTECIIYCPRVRTGDETVIIGEDQKAHI
                     SEELCVGCGICVKKCPFEAIDIVSLPEELEHPTHRYGENGFALYGLPIPAEGRVTGIL
                     GPNGIGKTTAIKILSGQLRPNLGILHGEAAWQDVLKLYAGTELFDYLQIISQKKMRVA
                     IKPQYIDYIPRVFSGTPRELLKNTDERGKLESLIGAMGLSSILDSDVATLSGGELQRV
                     AIVACLARDADFYFLDEITPFLDIYQRVAAANLIRETATRRPIVIVEHDLAVLDMLAD
                     VVHVAYGKPAVFGVITQPKGVRVGINEYLGGYLPEENVRFREYPVIFEKRAHTKGAER
                     ATLLEFPRMEKTYPHFHLEVSGGDIRAGEVLGVLGPNGIGKSTFARLLAGVETPDGGA
                     VQISAKVSYKPQYIKAESPDTVEFYLRSCTKQFDTSIYQHDIIEPLSLGPLLQSSLDT
                     LSGGELQRVAIAACLSRPADLYVLDEPSAHLDVEQRVRITRMFRHYVDGRDAAILVID
                     HDIYLIDMISERILVFDGEPGVRGEATGPFGMREGMNRFLSRLNVTFRRDKSGRPRIN
                     KPGSFLDREQKATGEYYYYTEKEEVA"
     gene            complement(13147..13665)
                     /locus_tag="PK679_07330"
     CDS             complement(13147..13665)
                     /locus_tag="PK679_07330"
                     /inference="COORDINATES: protein motif:HMM:NF039857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55805.1"
                     /translation="MSAKLPGKKGKDPAKKSFMERYRETLEREKAAREREKQKKLKAL
                     GPAEEDAGAGDEPDETPVAIETPRKKTREEKKAEHLARIYKTLIASIIGIVTGVVSYI
                     LVEPRLVAGIQAYTVLAFLIMLAGIVVQRHIFILLKLGAHPMGAKDWLYQGFMTFAFW
                     FIAWTILLTQGT"
     gene            13724..15625
                     /gene="rqcH"
                     /locus_tag="PK679_07335"
     CDS             13724..15625
                     /gene="rqcH"
                     /locus_tag="PK679_07335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome rescue protein RqcH"
                     /protein_id="HPC55806.1"
                     /translation="MATAQGLSGIDVRALVTEWERLLPLWVDKAYEVAPGTILLRFKG
                     KEHGRHALVIEPPVRAHLTWHEVAVPKTPSAFAMLLRKYLSGGRVLSIRQHGIQRIVI
                     FDIGKGDRLYHLVIELFDRGNIVLCASDWTIIQPFRRLHFREREIVAGAAYTLPPEGP
                     ATAGPEEFARFLAGESRDIVRALAVGAMLGGAYAEYLCRKAGIDKKTEAGKAGAGPLY
                     TGVENLLKRASEGIAPVITKDSCLPFPLDEGGTPAAAAPGFNQALDAFFPPPAPPGGE
                     EVTRKEEKARRDDHIRSRQQEAVKKFEEKIAACERAVEALYSHYTLVSEILEALRKAR
                     ETRSWQEIEALVRGAKSGPATRIVAVYPGRGAVDIDLGERVTLTVGESIEANAAAYYE
                     EIKKYRRKIAGAQAAMERAVQKKERRTVRAAAGKKRWYHRFRWFITSDGVLVVGGRDA
                     SQNEELVKKYMEGSDLFVHADVHGASVVIVKGKTGKMDEVATFAASYSGAWKSGHLAA
                     DVYCVAPSQVSKTPESGEYVSRGSFIVRGERRYFRNVPLGIAIGLRKEPEPEVIGGPP
                     AAVQAYAPLSVMLVPGRFEPNDAAKKALRALREKLSPDEQREYKKILTTEAVAAFVPA
                     GGSDIMEAR"
     gene            15622..16647
                     /locus_tag="PK679_07340"
     CDS             15622..16647
                     /locus_tag="PK679_07340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mRNA surveillance protein pelota"
                     /protein_id="HPC55807.1"
                     /translation="MKAEAADRKQEYGEIRLFPENADDLWHLSHLISPGDLVFATTFR
                     TVDAPSDKIRPEKLEKKPVRLGIRVERVELHDYSNRLRISGTIEHGMDAGAHHTINVE
                     PGYEISVIRHWKPHDLERIERAVKASVHEPVHVLAIEEGEAVLFRMRQSGPEEVTTVT
                     MGSGKGSDTDSRPAFFARVAEEVSPVRGPLVIAGPGFIKEDFFRFLATRNPGLAERVI
                     LVETRRPGQGAVGEVLGQGVLDKITEDVQLGREVRAVEELLMRIAKDLPVAYGKRDVE
                     TAVDFGAAEEVMVCDSLLHDGGIVRLLEKAEQQRARVTILSERFDPGKQLAALGGVAA
                     LLRFRIQ"
     gene            complement(16769..>18280)
                     /locus_tag="PK679_07345"
     CDS             complement(16769..>18280)
                     /locus_tag="PK679_07345"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55808.1"
                     /translation="TPTITPTPTVTPTPTATPTPTASPTPTPTVTPTVSPTPTSTIIP
                     VMPHEFYGTVTIRDGEPAPAGARVEARVPGVYKGNGNPVTVVTPGQYGGPGTTDPRLL
                     VFGVIDNAAPIEFYVDGIRAECQDAETSGAWMATYPFRAGQLTHLNLRTNSTVPVVDF
                     TAEPTYGMEMLEVHFYDTSIGYPTGWLWDFGDGKSSSEQNPVHTYRYGKYTVTLTAWN
                     SKGSGNMTKVHYIDVRSAAGGGGGGGGGGGIGGGTYLSVGTSTATATPTPTPAPTAQP
                     GTTLGTGSSLPLNSALTLSQSVTIVSQDGAGSLFLPNGMKPEDASGAPLRNLTIRRIA
                     GSEVPGTSAPGFTFAGYAYEIEPSGATFDPYITFSITVTESDWNALQGADLSIKWFNP
                     ATSAWENLPTTVDSTSRTVSTKLTHTSVYALFRAGTQATPVVTEPVTTVTTAAGSSAP
                     GLPLDLIVKIVIVAIIVIAAVSVAFYFIRRKKEPAAPAEKETPEEDWEIKGLK"
     assembly_gap    18281..18380
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<18381..18894)
                     /locus_tag="PK679_07350"
     CDS             complement(<18381..18894)
                     /locus_tag="PK679_07350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55809.1"
                     /translation="MSTKILIFFLVIGLMTGIVAADSLLPPPLPCTYYGTVTINGAPA
                     PVGTLIETKVYGTVRGDITVSTAGSYTGLMAWVSSSEYECGCTIPVQFYVNGYLAPQT
                     STFSAGDSKNVNLVLTGIPTPTITPTPTVTPTPTATPTPTLTPTPTPTASPTPTITPT
                     PTVTPTPTATP"
     gene            complement(18928..>19755)
                     /locus_tag="PK679_07355"
     CDS             complement(18928..>19755)
                     /locus_tag="PK679_07355"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55810.1"
                     /translation="ESNTALQADFSGSPTYGPAPLSVQFTDISIGSPATWEWDFGDGY
                     TSNEENPLHVYESPGTYAVTLTVTGISGTSSTTKNGYITVTAGPTYTGTPTPTPTTPP
                     ASTMRLYPGWNFVSTPKALADGHNTVGTVFIGVVDTGGRSIFLYDAGSMSWQQMTAES
                     MIRPLDGIWIYSTGTVDVPLTYKNDPLATPPTKDLATGWNAIGFSDVSPASAKDTLTS
                     VRNQWTQVIGFNAAAQAYDASLINGGSGSHSDTNPMYPFKGYWLFMNSPGTLAAISA"
BASE COUNT         3699 a         5809 c         6198 g         3949 t
ORIGIN      
        1 cccggcgaca acgaccgctc cggcatcaga cctctgttcc ctctgcctcg agtctgaccc
       61 tgcatccgcc ctcgtgacca tagacggtat tgaaagaggg gtcaccccga tctgcgtgcc
      121 cctcgcgccg ggcactcacc ggatcaccat ctcgaaggaa ggctatgtcc cgtgggaggg
      181 agagatcaca acaggagcgt cccagacact gtccctgccg gtcttttcac tccggcccgt
      241 tgcccggttc gtcgtagagg cagggtgcag tcccggcggg gcagtcctgc cggaaggacc
      301 ggtccgggtt ccgaaagggg gaaccgtgga gttcctcttt gtcccggaga cggggtacga
      361 gctcgttgat gtcctcgttg acggcagatc catcgggccg cacccgcgca cgaggctcga
      421 gggtatttcc cggaaccaca cggtccgggg tgtgttctca ccggtcactc cctcttcccc
      481 tgttgctgct atactggcca acagcaccga tggggtggca ccgctcgccg tgcagttcca
      541 ggacgtctct gagggcgacg ttgcaaacag gtcgtgggac tttggggacg gcacctcgtc
      601 gaccgatccc tcccctgtcc atgtctttta tgagccgggg aactatacgg tcacactcgg
      661 ggtctgcggc cggggcggct gcaacctgtc agcaccatcc tgcctgatag tcgtgcggga
      721 ggggagtacg ggcggaaacg ggacatccgg tgaaagcggg ggagggggtg tgacacccgg
      781 tgcagacgat gacaacccgc cgctcatcgg cgggagtacg ggttttctca gggtcaggtg
      841 cccggtcgaa ggggcatccg ttttcattga cggggattac aggggagaga tcaggaacgg
      901 gaccctcgat atcctcattt acctgacggg gactccctgc cgggcagtga ccgtcaaggc
      961 accgggatac ctgccggcaa ccgtcccgat cagccggtac cctgacgagg gagagacagt
     1021 ggtcatcgaa gtcgccccca tcctgatcgg accctccccc ggtgtcttcg aagggcaagg
     1081 ccggtcgtct cctcttcccg gaaacgtgac gcccacgata ccctcattgt catccgggtg
     1141 agacaaccag ttttggtaca tgctcaactt tttatcctcc caaccccatc taaagggaga
     1201 tggaaccaga tggcgacgac gggctctccc cccggaaggt gtcatacctc aagttcctcc
     1261 gcgagagggg aaacgcggca aggacgggtg agattgcaga acggttctcg gttgacccgt
     1321 caacggtgac acgggccgtc caggagcttg cggcagccgg actcgtcttc caccagccct
     1381 acggcagggt taccctcacg gagaaaggcg ttgcccgtgc cgattttctc gtctggcggc
     1441 accgcgttct cgggctggtc ctctcccatt acgggcttgc aggggaagag gcctgccggg
     1501 aggcagaaag gttcgaggcg tatgtctcgg caggagcagt ccggaggatc tgcgcatcgc
     1561 tcggtcaccc cacgaggggg atctgcggtg ccatctgcca cgatgccctc tgcggggcgg
     1621 aaaaggaaga ggagaatttt tgagggagta ccaaaataat gtggcccgga caatcgcacc
     1681 cttttcatcc acaattccgg cgtgcggtgc ctctcatgct cgtcattctt gttgcgatct
     1741 ccgggtgcct ctcggaaggg acggacggac ggggcacccc ccacgggaag acggcggtgg
     1801 tgaccattct gccccaggca gagatcgtca gggagattgc cggcggggac tgggaagtcg
     1861 tcgtcgtcgt ccctcccggg gtcgagccgc atacctacga gccgaccgcg tcccaggtcg
     1921 cacgggtgag ccgggcggac gcgtacgtca ggctcggccc cgatctcatg ccctttgagg
     1981 acaccctcgt ccagcgtatc acagcacggg aaccggggat cgcaattatc gatatgtccg
     2041 agggcatttc cctgctctat ggcgacggaa aaggggatga ggggaccacc cggagccgga
     2101 caggtgccga tccccacatc tggctctcgc ccgcaaacct ccgcatcatg gcagaaaatg
     2161 ttgcacgggg actttctgaa ctcgatcctg cccacgcggc cgattacgct gcaaggaaaa
     2221 acgcgtacct cgggaagatt gattcctgca ccggtgccat ccggagaaac gtatcgggcc
     2281 ttgaaggcag gtcgttcctc gtcttccatc cagccttcgg ttacttcgcc cgcgactttt
     2341 cgctcaatca ggtggcagtc ggggaagggg gccacgaacc cggtcctgca gggctctccc
     2401 gcctggtcag cctcgcgcgg gaagagggaa tatccgtggt ctttgccgag ccccagttca
     2461 gcacgaggga gagcgaggtc attgcacgcg agataaacgg gacggtggtc cttgtcgacc
     2521 cgctcgcccc ggatgtcctt gagaacctgg tccggatatc gggcgcaatc aggaatagtt
     2581 atggtgtggg atgacgcgga cgggtgatcc ccggatgaga cctgtcatcg aggtgagcga
     2641 tgtctcgttt ggacacaacg ggaaagtgat tcttgaacac gtctccctca aggtcaggaa
     2701 aggcgacttt tttgccctca tcggtccaaa cggcggagga aagacaacgc ttctgaagat
     2761 catcctcggt ctcctcgtcc cttcgggcgg gactgtcacg gtgctcgggc aacctcccgg
     2821 gagggcacgg tcacgggtcg gatacgtccc ccagttcagg acgtacgact tttcgtaccc
     2881 catcaccgtc cgggagatgg tcctttccgg gaggctctcc catgccaggt tcccctgggc
     2941 gaggtacacg cctgccgacc acgaggccgc agaccgcata ctcgaacggt tgaggatggc
     3001 acccctcgcg gaaaggcccg tctctgcgct ttcgggagga gagcagcagc gggcgatcct
     3061 tgcccgggca ctcgtgggaa accccgaggt cctcatcctc gacgaaccga cggtctacat
     3121 cgatgccccg acagaggtcc atttctacaa catcctcgaa gatctcagga aagacctgac
     3181 cgttctcctg gtcagccatg acatcggggt catctcccgc catgtgacac gtgtcgcgtg
     3241 cctgaaccgc aggctgttta cccacgattc tcccgagatc accgaagaca tgatcgaggc
     3301 ggcctaccag tgcccggtcg acctcatagc ccacggcatc ccccaccggg tgctcgggga
     3361 tcaccccggg gagggaggtt cgcgatgatg gacgcgggca tcctttcgtt tggtttcttc
     3421 cagaacgcaa tccttgcagc agtgctcgcg agtatcgcgt gcggtatcat cgggagcctc
     3481 gttgtcgtca agcgcatggt caccgtcagc gggggcatct cgcacgcggc attcggggga
     3541 gtcgggctgg gatacctttt ttccatcgac ccgatcgtgg gggccttctt cttctctgtc
     3601 ggcgtggccc tgtgcatcgg cattgtaaaa gagaaggccg ggcaggagat cgatacactc
     3661 atcggggcag tctgggcagc cgggatggcg gtcgggatca tctcggtcag ccttgccgag
     3721 gggtataccc ccgacctctt cagctacctg tttggaaaca tcctgctcgt gccacagggg
     3781 gatatcatcc tcatggcagt cttttctgct tgcatcgtcg ccatcgtcgc ccttttctat
     3841 cttcccctcc aggcggtcac gttcgacgag gagtatgccc gggtcatgaa cctgcccgtg
     3901 acggcactct ccctcgtcct cctcgtcctc acggcgacct gcgtcatcat cctgatcagg
     3961 ctcgtcggga taatcctcgg catcgcactc ctggtccttc ccgcggcgag cgtgcgcggg
     4021 tttacgaccc gcctcccgac aatgatggca gcatcggttg tccttgccct cgtcctctcg
     4081 ttatcggggc tgttcctctc gtatgcctgg gacctcccct ccggggcaac gatcatcctc
     4141 ctcggggcag ccgtgtacgc agtctccctc gtcctctccc ggttcagccc ggcccggcgg
     4201 tggggaggcg gcacgcgcag cgaccgacgg ttgccgcaac aagaagggcc agaagggcgg
     4261 tgagggtata tgcagcggga aaacctcccg tttccgcaac gaaccctgca atgaagggga
     4321 cggctgtcat ccccccgtaa cttgcggtgt tgaagagacc catcaggaca ccctggcggg
     4381 ccccggcggc cgcaaggaag gagagctggg agatcatcac catcccggcg agccatccta
     4441 ttacgaggaa gccccacatc gagtagaagg tgagagcgac tccgcctgcc atcgccacgg
     4501 ctgcaagctg gatcgtcctg accgggggca ggtttgcacg cgacgtcacg atgaccgatg
     4561 caatcgtggc agcgttcatg agagcgatct ttccggagac ggaagaggca gggagatccg
     4621 tgaactcggg gtaaagggcg gtgacggctc ccgtgatccc gaccaggaca acggcagaga
     4681 cccagagcca gaaatacgtc cggaatgccc ataccagcct ctttttcgtc tcctgtgccg
     4741 gttctgcggg gaccctgtga gacatttcct gtccccttcc cgtggcaaaa gcgaggacga
     4801 gggggacgac cgagagccag gtaaaaaaga tgattccccc gcggctgctg cccgggctgc
     4861 cggtcacgag ccacccggtc acgaggagac cgaggatgag gccaaggttc aggagaccca
     4921 tgaagtaacc gctcatccgg tcgtggtcag gccgggcatt cagaaatgca agagacgcag
     4981 gcacgaagag gcctgccccg atcccctcga cgagccgggc aaggaaaaca agcaggggcg
     5041 agcctgcaag ggcgaggagg acgcccgaga gggttgtgag gacaaggccg gcccggatga
     5101 gggggacttc gccgatccgg tcggaaacgt agccggcagg caggacgagg aggaatgcac
     5161 cgaggaagta ggcagagtaa attgcgccct gggctgcggc cccggtcgaa aaagagggaa
     5221 ggacggggac aatggcattc gagagtgcca tgaccgagaa ggcaccggca aggaggggca
     5281 ggttctcctt cataccatcc ggtacgtctc caggttcatg ggcgaatggg tctcgatgtg
     5341 gtacctcttg tagatggaac tggcaaggtc aattgtgttg ttctcatcgc cgtgcacggt
     5401 gaagatcttt tcgggccgtg gctggacgtg ggcgatgaaa ctcatcagct gtttccggtc
     5461 ggaatgcccg gagaacccgt cgattgtcac gatctcgagg ttgatcacga ttgtgccttt
     5521 cctgccgatg gggacttcac gccacccttt ctggatgcgc cgcccgagtg tcccctccgc
     5581 ctggtacccg acgaagacga gcgcattttt ctcgtcggac gcgaggttgc ttaagtattc
     5641 catgacggga ccgccgttga gcatgcctga cgtcgtgatg atgacgcagg gatcgcccat
     5701 gatgaccttt tcccggagtt cggaggaatc gacggggacg aagcagtcgg caaggaaggg
     5761 gttatggtcc tccttgaata tctgggtcct cagctcgctg ttcaagtact cggggtaggt
     5821 cgtgtggatg gccgttgcct cccggatcat cccgtcgagg tagatcttca ccgtcggtat
     5881 cttctgcctg cgcataccct cctcgagcgc gagcatcact tcctgcgacc tcccgacggc
     5941 aaacgcgggg atgatgacct ttccacccct gcggatggtg ttgttgacgg tctcgtacag
     6001 tttctcctcg gcctcggcac gggtgggctg gatgtctccg gaacccccgt aggtgctttc
     6061 catgatcagg gcctcgagcc tggggaagtt gcaggtcgcc gggttgaaga gccggctctt
     6121 gctgaagttg aagtcaccgg taaaagcgat gttgtacagc ccgtcgccga tgtggaagtg
     6181 ggcaatcgcg gaaccgagga tgtgcccggc gttgtggaac gtcagcttga tgtcaggagc
     6241 gatgtccgtg acactgccgt aattgagggt gatcgagtgc ttgatgtagc tcttgacctc
     6301 gtttgagctg tagggaatct tcctgtcttc cttgctcacc acgtccaggt aatcgagctg
     6361 gagcattgcc gagaggtccc tcgtgggcgg ggtgctgtaa acgggcccgt cgtacccgta
     6421 cttgaagagg agggggacga gggcacagtg gtccaggtgg gcgtgggtga ggacgaccgc
     6481 gtccagctgg ctgagggggt ggatctcggg gacgtagagg taaggcgtgc tcgcgctgtt
     6541 gtcgggtttt tccccgcagt cgatgaggac cctcgattcg ggggtggaga ggaggaacgc
     6601 tgcacgtccc acctcgcggc agcacccgag catcgtcacc ctgacccact ggtcccgtgc
     6661 gatcacgtcg cggtggatcc tccggccgat tgcccggagg aactccttcc tctcctcgtt
     6721 gaccgagcgc aggtactgcc tgatctgctt gacggtactc gattctatgg ggggtgtccg
     6781 cacgaccttg ggcgtccatc cgatgtgccg ggtaatctcc cgaagggttg caccgttctt
     6841 cccgatgaca acgcccggct tttcggcctc gatgaggact tcaccggtat ccgcgtcaaa
     6901 aaatatatcg gtgattcctg cgttctctgc gacaacggcc ctgatatccc tgatagcctt
     6961 ttcgggatct tcgaggacat tgggacggac gacgatccgc ttgcgcaggt cccgtgcgag
     7021 gacctttatc aggtcagcct ggtcggcaaa cctcttgggg tcgtccgtgt agatgacgag
     7081 ttcaggcccc tcgaactcca cgtccgagac cgtgatcccg gcaggtactt tctcgttgat
     7141 cttgtctttg agctctttga gccgctcttc gataagcatc aaaaccgacc taaaaaagta
     7201 ttacgcgggg gataccgggg aaagaccggc gatttcactc tcggtcagct ccctgtaggc
     7261 ttctttcgtg atgaccacca cgtggatgcc ctcgccggaa cccgcgtccc tcttcattgc
     7321 cgaccggatt gccctgacgg caagcgcgac tgcctcgtcc tcggagagat ctttgctgta
     7381 gcggtcttca aggacaccga aggccatcgg ggaacccgat ccggtcgcca ccatctcctc
     7441 ctcgcgggac gcacccccga gagcatcgac tgcatagagt ttcgggccgc cctcgtcgac
     7501 gccgcccacc agcagctgga cgtagaaggg gtaataccgg ttcgcgttca ggatgttcga
     7561 gagcagggtt gcgaccgccc cgatggttat cggcctgccg cgcctgatct ggtagaggct
     7621 gcactccact gtcatcaggc gtgcgatctg ctgtgcgtca ccgactcccc cggcggttgt
     7681 catccctatc ctgtcggcaa tctggtagat cttcttggct ttcttggagg cgatcaggta
     7741 ccccatcgtg gccctcatct cggatgcaag cacaactgca tcgcgaagga cgagtccgac
     7801 ggtggttgtc cctgtcattc cttccctgta ttgttcattc atggaaacac cccaaaatat
     7861 tggaaaacgc tggtaaattg ccttaaaagc gcttcaaaca gtacaatgtc atcctaaaac
     7921 ataaacattt ttgtcagggc ctgtccttgc agagagccct gatgagctcc ctgtcaaaga
     7981 gcatcgccac gagtttccgg tccccgttca cgacgggcag ctggtccacc cgtgccctct
     8041 tcatcttgag tgcacactcg ctcacctcgg cgttcagcgg caccgagatg acgttcctga
     8101 ccatggctgt cttgaccggg cggttgggga gctggatctt ggatatgccg taactgattg
     8161 tgtgcatgtc gcggatgctc tcccacgtcc actcgtcgtc atccgtgccg ttcgaaaagt
     8221 cgctcacctc gaccgtgtcc tcgatcgagg agtgccggat gaggtcgcgc tccgagatga
     8281 tcccctggag gatactctcc tcgtcgagga tggggattgc gtcaaagccc gagatctcca
     8341 tgatacggcc gacgagaggg agaggcgtct cttcccagag ggcaaacgtc tggctgatgt
     8401 aggattcctt gatctcgtcc cttaccttca tctgcgccag tgccgcaacg agatccgcga
     8461 ccgagatgag gcccacgagg tcatcgtcct cgatgaccgg caggcggcgg atggaatgct
     8521 tgatcatcag ggatgcggcc tcccggatgg ttgcatcagg cgaaatcgtt atcggatcat
     8581 gcgtcatcag gagaccgagc tgcgtctcct ctgccttccg caggaggtcc tttctcgtga
     8641 tgatacccac gagttttccg tccttgagaa ccgggacacc cgatatcccg gtgcgcttga
     8701 gtatcttgag gacgtcgtcg cggttcccgg ggatctccac ggagaccacg tcggtggtca
     8761 tgaagtctga tactttcatt tctgtgatgg tctcaccacc agaacagcca ctttgctgtt
     8821 gctgaccaca aaagaactga cactgccgag gaggagcctg tccacctcgc tcttgccgtg
     8881 ggagccgaca acgatgaggt ctgcaccgac ttcccccgct gtcctgacga tctcgtttcc
     8941 cgcgtggccc tggcggatgt gcgtctcgag tgccacgcct gccttttgcg ctgcctcttt
     9001 tgcacgttca agggtctcct gaccctcttt ctcgagcatg ctgaacatga tctcccacgt
     9061 gctgtccatg ggcagggacg aaaacaaccc tgtctccaca acgtacacca catggacctt
     9121 tgccttccag acacgggcct catcgagggc aacctcgaat gccctcctcc ccatgttcga
     9181 cccgtcaaca gcgaccagga tatccgagaa catcagtaca ctccaaaaca gtctgcctat
     9241 gtaatgtctt ttacaaatta ataacctttc tcacgatatt tgccggacct gccctgttta
     9301 cgagggctgc tgcaatgtcc cggctcagtg agaggttcga tggacgggga tcgatgacca
     9361 gaaaagcggc cctgtttccc tccctgatgt aaaaaggttc catgaagagc gatgccccga
     9421 gggttgcggc gcgcagtgcc tcgcgcgggg agacgcggta aacggtggag aggaactcca
     9481 tctccctcca catgtccggc tggacacaca tcgcgttgtc agtcccgagg aggatggtgc
     9541 ctccgaggga gaggagttcc cgcacgggag gtctcatccc ggacgacgtg acgcggaacc
     9601 tccagtttgc cctcggacag acggcaacgg gtatgccggc gtccgcgatc tgccggagtt
     9661 gatccttcga agcgtgcgtg cagtggacga ggagatccgg ttcgtacgcg agggcctgcc
     9721 cgatgtcaga gggatccctt tccccggcgt ggaatgcaac gagttttcct atccggcgtg
     9781 cgagggatac catctcgtcg aggctgcctc caacgtcacg tgcgctgctt attccaaggc
     9841 cctgcgcgac catctcgccc ccctcgcgcc cgaagatgac gggccggcag gaaataccct
     9901 ccgcggcctc gagcagcgcg gatacgccgt ccctgccccc ttcccggaaa tcggcgaacc
     9961 ctgccgtgcc cccgtgagcc atagtcccga tggtcagccg catcgccctg acgagttccg
    10021 tgcgggatac cgaccggagg atacggtgct tgagcccgtc ggggggtcgg acgagtgcat
    10081 cgaggtcacc ctcgagcgga atgtcgaggg caacactgtc gccgacatgg gtgtgggcat
    10141 tgaagaatgc agggacgatc cagggcaggt cgtttccggg tcccccgagc tcctcgatgt
    10201 gcgcgatggt gccgccctca acgaccaccc gcacgggcgc ctcctcgaag tcctcaccaa
    10261 ggagggcgcg tccctcgacc aggagttccc cgccgctcat gtctgctgcc agccttttat
    10321 ataccgagaa tgagaaatat gtttgtatgg caaagaagca gggtggacgc ctcatatcct
    10381 ccgcagggct ggtcaattac tacgagagcg aggacaagag ggcaatacac atcagcccgt
    10441 actcggtcat catcgtgtgc gctgcaatcg gcgtggcgat cctcgttctg aatatcatct
    10501 actaaaaacc cttctttagc ggtttttccg attcctcttt ttttccatcc ggaatcctgt
    10561 ctctcccccg tcccggtgac atactgatgg gatctttccg ggggaaatgt tctccccctg
    10621 taacgggaat accaaggcac aaagggaatc agccgcctgg actggggtga ccgttggatc
    10681 cccggatacg tcgatattta tataccgtgg gagctgtaat caccaattgc cgatgttcct
    10741 catcatccgc tgccccgggt gccggacttt ttcctacgtc gaccggttcc agcagtggaa
    10801 gctctgcccg gtctgtggag aggcgatcga ggtcgcgaag gcccccgcgt acatcgaggt
    10861 ggacgagtac cgggttgccg agcgtatcgt cagccagctc gaggattacc tccacaggaa
    10921 ccggaagaag gacctttctc ccgaggaact ggcggcactc cgcgagcagt atgccgagtg
    10981 gctccggagc aaggcatgag aaaagaccgt caccatttct tcccgcatcc cgggcagacc
    11041 agtgtgatct cgcgcctgca ccgtgggcag aagagccctg tcctctcgtt gtagaccacc
    11101 gtggatccgc acctgcggca gaggatctcc tgttcgtacc cgcactcgtg ccggaccatg
    11161 aggaggatat ggcagaaggg ggatgaaaaa ggttctcacc ccggtggtct ctccatcatc
    11221 gggcagtcat gggatggcaa cgcttcttcc gatcggcctg ccgggggact tcaggggatg
    11281 gcaacccgga ttcggatatc ctgctgaaag gacaaaaaag ggaagggagg tcggggggaa
    11341 gatcacgcca cctcttcctt ctccgtgtag taataatact cccccgtcgc cttctgttcc
    11401 cggtcgagga acgagccggg cttgttgatc cggggccgcc cggacttgtc gcggcggaag
    11461 gtgacgttca gccgcgagag gaacctgttc atgccctccc gcatcccgaa aggcccggtc
    11521 gcctccccgc ggacacccgg ttcgccgtca aagaccagta tccgctcgct tatcatgtcg
    11581 atgaggtaga tgtcgtggtc gataacaagg atggccgcat cccgcccgtc cacgtaatgg
    11641 cggaacatcc gcgttatcct gacccgctgc tcgacgtcaa ggtgtgcact gggctcgtcg
    11701 aggacgtaga ggtcggcggg ccgcgagagg catgccgcga tggcgacacg ctggagttcc
    11761 ccgccggaga gcgtatcaag ggaagactgc agcagcggcc cgagggagag gggttcgatg
    11821 atatcgtgct ggtagatcga ggtatcgaac tgcttcgtgc acgaccgcag gtagaactcg
    11881 acagtgtccg ggctctcggc cttgatatac tggggcttgt acgagacctt cgcggagatc
    11941 tgaacggcac cgccgtccgg cgtctccaca ccggcaagga gccgggcaaa cgtgctcttc
    12001 ccgatgccgt tcgggccgag cacaccgagg acttccccgg cccggatgtc ccccccggag
    12061 acttccaggt ggaagtgggg gtaggtcttt tccatgcgcg ggaattcgag aagtgtcgcc
    12121 ctctctgccc ccttcgtgtg cgcccttttt tcgaagatga cggggtattc cctgaaccgg
    12181 acgttttctt ccgggaggta cccgccgagg tactcgttga ttcccacccg gacgcccttt
    12241 ggctgcgtga tgacaccaaa gacagcaggt ttgccgtagg cgacgtgcac gacgtcggcc
    12301 agcatgtcga ggacggcgag gtcatgttcc acgatgacga tgggtctccg ggtggcggtc
    12361 tcccggatga ggtttgctgc cgcgactctc tggtagatat cgaggaatgg cgttatctcg
    12421 tcgaggaagt agaagtccgc gtcccgggca agacacgcaa cgattgccac cctctggagt
    12481 tcacccccgg aaagcgtcgc aacgtcgctg tcgaggatgg atgaaaggcc cattgcaccg
    12541 atgagggatt cgagttttcc ccgttcatcc gtgttcttca ggagttcccg cggggtgccg
    12601 gagaagaccc ggggaatgta gtcgatgtac tggggcttga tggcgaccct catctttttc
    12661 tgggagatga tctggagata atcgaagagc tccgtcccgg cgtacagttt cagcacgtcc
    12721 tgccatgcgg cttcgccatg gaggatcccg aggttgggcc gcagctgccc cgagaggatc
    12781 ttgatcgcgg tggtctttcc gatgccgttt ggaccgagga tgccggtcac cctcccctcg
    12841 gcagggatgg gcaggccgta cagtgcaaaa ccgttctccc cgtaccggtg cgtggggtgt
    12901 tcgagttcct cgggcaggct cacgatatcg atggcctcga acgggcattt cttgacgcaa
    12961 ataccgcacc cgacgcagag ctcctcggag atgtgagctt tctggtcttc cccgatgatg
    13021 accgtctcgt cacccgtgcg tacccgcggg cagtagatga tgcattcggt cccgcatttc
    13081 ctggggtgac accgatccct gtggacgact gcgatccgca tggaaaaacc cctggaaaac
    13141 ctcctttcag gttccctgcg tgaggaggat ggtccaggcg atgaaccaga atgcaaaagt
    13201 catgaatccc tggtagagcc agtcctttgc acccatgggg tgtgcgccaa gcttgaggag
    13261 gatgaagatg tgcctctgga cgacgatgcc ggcgagcatg atgagaaatg caaggactgt
    13321 ataggcctgg ataccggcga caagccgggg ttcgacgagg atatacgaca cgacccccgt
    13381 cacgataccg atgatcgatg caatcagggt cttgtaaatc cgggcaaggt gttctgcctt
    13441 tttctcttcg cgtgtcttct tccgtggtgt ttcgatggca accggcgtct cgtcaggctc
    13501 gtccccggcc ccggcatcct cttccgctgg cccgagggct tttaactttt tctgcttctc
    13561 cctctccctc gcggccttct ctctctcaag ggtctccctg tacctctcca tgaatgattt
    13621 ctttgccggg tccttgcctt ttttgccggg gagttttgca ctcattggga acaccagtag
    13681 tcctattttt aggtgcttga gccatatcta atttggtata ccgatggcaa cagcccaggg
    13741 actgagcggc atcgacgtgc gggccctcgt gacagagtgg gaacgcctcc tgcccctgtg
    13801 ggtcgacaag gcctacgagg ttgcacccgg gaccattctc ctgcgtttca aggggaagga
    13861 acatggcagg catgccctcg tcatcgagcc cccggtcagg gcccacctca cctggcacga
    13921 ggtagcggtc ccgaaaacgc cctcggcatt tgccatgctc ctgcgcaagt acctctcggg
    13981 ggggagagtc ctttccatcc ggcagcacgg gatccagcgc atcgtcattt tcgacatcgg
    14041 aaagggcgat cgtctctacc acctcgtcat cgagctcttc gaccgcggga atatcgtcct
    14101 gtgcgccagt gactggacga tcatccagcc gttcaggcgg ttgcatttca gggagaggga
    14161 gatcgttgcc ggggcagcct acacgctccc tcccgaggga ccagcaacgg cgggtcccga
    14221 agagttcgcg cgtttcctgg ccggagagtc aagggacatc gtccgggccc ttgccgtcgg
    14281 agcgatgctc gggggggcct atgccgagta cctctgccgc aaagcaggta tcgacaagaa
    14341 gacagaggcc ggaaaagccg gggccggccc cctctacacc ggggtggaga acctcctgaa
    14401 acgtgcatca gaggggattg caccggtcat cacgaaggat tcatgcctgc cgttcccgct
    14461 cgatgaagga ggtacgccgg cggctgccgc tcccggtttc aaccaggcac tcgatgcctt
    14521 cttccccccg ccggcacccc ccggtggaga ggaggtcacc cggaaagagg agaaggcccg
    14581 ccgggacgac catatccggt cccggcagca ggaggcagtg aagaaattcg aggaaaagat
    14641 tgcggcatgc gagcgggctg tcgaggcact ctactcacac tataccctcg tcagcgagat
    14701 cctcgaagcc ctcaggaagg cacgggagac ccggtcctgg caggagatag aggcactcgt
    14761 gcggggagca aagagcgggc ctgccacccg catcgtcgca gtgtatcccg ggcgcggggc
    14821 agtcgacatc gaccttggcg aacgtgtcac cctgaccgtc ggggagagca tcgaggcgaa
    14881 tgctgctgcc tattacgagg agataaagaa atacaggcgg aagattgcgg gtgcacaggc
    14941 agccatggag agggcggtcc aaaagaagga acgccgcacg gtccgggccg ctgccgggaa
    15001 gaagaggtgg taccacaggt tccgctggtt catcacatca gacggtgtcc tcgtcgtggg
    15061 cgggagggat gcgtcccaga acgaggagct cgtcaagaaa tacatggagg gcagtgacct
    15121 cttcgtccac gcggacgttc acggcgcatc cgtcgtgatc gtcaagggga agaccggaaa
    15181 gatggacgag gtcgcgacat ttgccgcatc ctactcgggg gcatggaaga gcgggcacct
    15241 cgcagccgac gtctattgcg ttgcaccctc gcaggtgagc aagacaccgg aatcgggcga
    15301 gtacgtgagc cgcgggtcgt tcatcgtgcg gggagagcgc cggtacttcc ggaacgtgcc
    15361 gctcggcata gccatcgggc tccggaaaga gcccgagccg gaggtgatcg gaggtccgcc
    15421 tgcagccgtg caggcatacg cgcccctctc cgtcatgctc gtgcccggca ggttcgagcc
    15481 caacgatgct gccaagaagg cattgcgggc tctcagggag aaactctctc ccgatgagca
    15541 gagggaatac aaaaagatcc tcaccacgga ggcagtagcg gcattcgttc ctgccggggg
    15601 atccgatatc atggaggccc gatgaaggca gaggcagcgg accggaagca ggagtacggt
    15661 gagatccgcc ttttcccgga gaacgccgat gacctctggc acctctcgca cctcatctct
    15721 cccggagacc tcgtgttcgc gaccacgttt cggaccgtcg atgcgccatc agacaaaata
    15781 aggcctgaaa aactggaaaa aaagcccgtg aggctcggga tccgcgtgga gagggtggaa
    15841 ctccatgact attccaaccg gctgaggata tcgggaacga tcgagcacgg catggacgct
    15901 ggcgcacacc acaccatcaa cgtggaaccc gggtacgaga tctcggtcat caggcactgg
    15961 aagccgcacg atctcgagcg gatcgaaagg gctgtgaagg catcggtcca cgagcccgtg
    16021 cacgtgctcg ccatcgagga gggcgaggcg gtcctcttcc gcatgcgcca gtcggggccg
    16081 gaggaggtga cgactgttac catggggagc ggcaagggga gcgacacgga ttcccgtcct
    16141 gcattctttg caagggttgc agaagaggtc tccccggtca ggggcccgct tgtcatcgcg
    16201 ggaccggggt tcatcaagga ggacttcttc cggttccttg cgacccgtaa tcccgggctt
    16261 gcagaacggg tcattctcgt cgagacacgc cgcccgggac agggagcggt cggagaggtg
    16321 ctcggccagg gtgtccttga taagatcacc gaggacgtgc agctcgggcg ggaggtccgg
    16381 gccgtcgagg agctgctcat gcggatcgcg aaggacctgc cggtggccta cgggaagcgg
    16441 gatgtcgaaa cggcagtcga tttcggtgct gccgaggaag tgatggtctg cgactcgctg
    16501 ctccatgacg ggggtatcgt ccggctcctc gagaaggcag aacagcagag ggcacgtgtc
    16561 acgatcctgt cggagcggtt cgatccggga aaacagctcg ctgcactggg cggtgtcgcg
    16621 gccctgttgc ggttcaggat ccagtagcgc gattttcctt tgggatggca gagaaacctc
    16681 ccggatggga tttcccccgg aaggcagaga gcgtcccatt ccggggacgc ggtttttata
    16741 aaaaatgaga ggggagagtc cggggccttt actttaggcc cttgatctcc cagtcttctt
    16801 caggtgtttc tttttcggca ggagcggcag gctccttctt cctgcggatg aagtagaagg
    16861 caaccgagac tgcagcgatc acgatgatcg caacgatgac gatcttgacg atcaggtcga
    16921 ggggcagtcc cggagcggac gaccctgccg cggtggtgac agtcgtcact ggttccgtta
    16981 cgacgggcgt ggcctgcgtc cctgcgcgga acagggcata gacactcgtg tgcgtcagtt
    17041 tcgtgctcac cgtcctcgag gtgctgtcca ccgtcgtggg gaggttctcc catgcagacg
    17101 tggccgggtt gaaccacttg atcgagaggt cggcgccctg gagtgcgttc cagtcactct
    17161 ccgtaacggt gatggagaac gtgatgtacg ggtcaaaggt cgcccccgag ggctctatct
    17221 cgtatgcata tcctgcaaag gtaaagcccg gggctgaggt tccgggcact tcagagcctg
    17281 caatcctcct gatcgtcagg ttccgcagcg gtgctccgga tgcgtcctcc ggcttcatgc
    17341 cgtttggcag gaagagcgat ccagccccgt cctgcgaaac gatggtcacc gactgggaga
    17401 gggtgagtgc cgagttgagc gggagggacg atccggtccc gagggttgtc cccggctggg
    17461 ccgtgggtgc aggagtcggg gtcggggttg ccgttgcagt cgatgtaccg acggacaggt
    17521 aggtgccacc gccgataccg ccgccaccac cgccaccacc gccgccgccc gcggcactgc
    17581 ggacgtcgat gtagtggacc tttgtcatgt taccgctgcc cttgctgttc catgcggtga
    17641 gggtgacggt atacttcccg tacctgtacg tgtggacagg gttctgctcg gacgaggact
    17701 tcccgtcgcc aaagtcccac agccacccgg tcgggtaccc gatcgaggta tcgtagaagt
    17761 ggacttcgag catctccatc ccgtaggtcg gttccgcggt gaagtcaacg acaggaacgg
    17821 tgctgttcgt ccggaggttg aggtgcgtca gctgcccggc acggaagggg tacgtggcca
    17881 tccaggcacc cgaagtctcg gcgtcctggc actctgccct tatcccgtcg acgtagaact
    17941 cgatcggcgc agcgttatcg atgacgccga agaccagcag cctcgggtcg gtcgtacccg
    18001 gtccgccgta ctgcccgggt gtcacgaccg tgacggggtt tccgttgccc ttgtacacac
    18061 ccggtacccg tgcctcgacg cgggcgccgg caggcgccgg ttcaccgtca cggatggtga
    18121 ctgtcccgta gaactcgtgg ggcatgacgg gtatgatggt ggatgtcggg gtcggtgaga
    18181 cagttggcgt cactgtcgga gtaggagtgg gtgatgctgt cggagtagga gttgcagtgg
    18241 gtgtcggggt caccgtgggt gtcggcgtga tggtgggagt nnnnnnnnnn nnnnnnnnnn
    18301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18361 nnnnnnnnnn nnnnnnnnnn taggagttgc agtgggtgtc ggggtcaccg tgggtgtcgg
    18421 cgtgatggtg ggagtgggtg atgctgtcgg agtaggagtg ggtgttaaag tgggagtagg
    18481 agttgcagtg ggtgtcgggg tcaccgtggg tgtcggcgtg atggtgggag tcggaatccc
    18541 cgtcaggaca aggttcacgt ttttggaatc accggccgag aatgtggatg tctgcggcgc
    18601 caggtacccg ttgacgtaaa attggacagg gatagtacat ccgcactcgt attccgatga
    18661 cgagacccag gccatgagtc ccgtgtagga ccctgcagtt gagacagtga tgtcaccccg
    18721 gactgtcccg tagaccttcg tttctatgag tgtccccacg ggagcagggg caccattgat
    18781 cgtgaccgtc ccgtaatagg tgcagggaag aggtggtggc aacaaagagt cggctgccac
    18841 gattccggtc atcagcccga ttaccaggaa aaaaatgagt attttggttg acattgctct
    18901 cctcgtggat gccgggacgt gccgcgatca ggcactgatc gcagccaggg tcccgggtga
    18961 gttcatgaac agccagtagc ccttgaacgg gtacatcggg ttcgtgtcgc tgtggctgcc
    19021 cgagccgccg ttgatcaggg acgcatcgta ggcctgcgct gccgcgttga acccgatcac
    19081 ctgggtccac tggttcctga cagaggtcag ggtatccttc gcactcgcag ggctcacgtc
    19141 agagaacccg atcgcgttcc agccggtggc aaggtccttt gtcggcggtg tcgccagcgg
    19201 gtcgttcttg tacgtcaggg gcacgtccac ggtaccggtc gagtagatcc agataccgtc
    19261 gagcggcctg atcatggatt ctgctgtcat ctgctgccac gacatgctcc ctgcatcgta
    19321 caggaagatg gaacggccgc ctgtgtcgac aacgccgatg aacacggtcc cgacggtgtt
    19381 gtgcccgtca gcaagtgcct tgggcgtcga gacgaagttc cagccggggt agagcctcat
    19441 cgtgcttgcc gggggtgtcg tcggggtcgg ggtgggagtt cccgtgtagg tcggtccggc
    19501 cgtgacagta atatacccgt tcttggtcgt ggaggaggtt cccgagatgc ccgtgacagt
    19561 gagggtcacc gcataggttc ccgggctctc gtacacgtgg agcgggttct cttcgttgga
    19621 ggtgtatccg tcaccgaagt cccactccca agtggccgga gacccaatag agatgtcagt
    19681 gaactggacg gagagcgggg caggcccgta cgtcggtgaa ccggagaagt ctgcctggag
    19741 ggcagtgttg ctctc
//
LOCUS       DAOOJU010000029        19661 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2757_length_19661_cov_15.338978, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000029 DAOOJU010000000
VERSION     DAOOJU010000029.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 19661)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19661)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19661
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2757_length_19661_cov_15.338978"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..432)
                     /gene="pdxT"
                     /locus_tag="PK679_07360"
     CDS             complement(<1..432)
                     /gene="pdxT"
                     /locus_tag="PK679_07360"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HPC55811.1"
                     /translation="MGVRLGVLALQGDVSEHILGFERALRVMGEADWAVIPVRKPGDL
                     EGLHGLAIPGGESTTISRLIGKNGLFEPLAGFEGGIFATCAGMVLVADRVDDPRVKPL
                     GLIDMAVQRNAFGRQRESFEADISVRGLGRPYRAYFIRAPVA"
     gene            complement(422..1318)
                     /gene="pdxS"
                     /locus_tag="PK679_07365"
     CDS             complement(422..1318)
                     /gene="pdxS"
                     /locus_tag="PK679_07365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HPC55812.1"
                     /translation="MKLEELRFGTELLKRGFASMQKGGVIMDVVNAEQARIAEDAGAV
                     AVMALERVPADIRKAGGVARMADPAIILEIMDAVSIPVMAKVRIGHFVEAQILESLGV
                     DMIDESEVLTPADEEYHIDKKAFSVPFVCGARDLGEALRRIHEGAAMIRTKGEAGTGN
                     VVEAVRHMRNIMGEIRALQGKTPQEITSRARELEAPPDLLLETVKMGRLPVVNFSAGG
                     IATPADAALMMQMGADGVFVGSGIFHSGNPEKMARAIVEAVNHYDDPKVIAEVSRGLG
                     QPMKGIDVHTLREDEVLQYRGR"
     gene            complement(1323..2246)
                     /gene="cbiB"
                     /locus_tag="PK679_07370"
     CDS             complement(1323..2246)
                     /gene="cbiB"
                     /locus_tag="PK679_07370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016880 - acid-ammonia (or amide) ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-phosphate synthase CbiB"
                     /protein_id="HPC55813.1"
                     /translation="MLIARLAVIPLSLLVDRVTGDPRSRFHPVALVGQFIAFWGDPRK
                     IRPSLQRAAGVVMWVATVALFSFPFYLAEAFLPWYALLVAAPVLLKVCLAWRSLEEHV
                     DAVERALSASLPEGREKVSYMVSRDPRELSADQVRSAAYESLSENLVDSIVAPLFYYA
                     LFGLAGAAVYRAANTMDAMLGYRDERERIGWFPARADDVLNYVPARLASGILLLYFAA
                     RGRYTPALRCLRQDAKKRPGFNGGLPMAVIAGGCGARFDKPGAYTIGPGERSLSDAGR
                     DIIGAVRACTLASAALFMLIPIFLALFIQFI"
     gene            complement(2353..2541)
                     /locus_tag="PK679_07375"
     CDS             complement(2353..2541)
                     /locus_tag="PK679_07375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methytransferase partner Trm112"
                     /protein_id="HPC55814.1"
                     /translation="MKRSLLPILCCPVCKGDLTLRVTLEDEKEIIEGVLQCPACGVDY
                     PIEEGIPDLLPREKKSKT"
     gene            complement(2538..3548)
                     /locus_tag="PK679_07380"
     CDS             complement(2538..3548)
                     /locus_tag="PK679_07380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthetase"
                     /protein_id="HPC55815.1"
                     /translation="MSCTIVVGGFFGDEGKGKIVAHLAYQDHPSIISRGGVGPNAGHT
                     VKMGEKEYGVRMVPSGFVYPHARLMIGTGVLVDPRVFAREVEMLGVGGRIFVDYRCAI
                     IDEGHIERDRSSSHLAKTIGSTGSGCGPANADRVLRVARLARDIPELGDYIADVPLEI
                     NSALDRGEHILLEGTQGFGISLYYGTYPYVTSKDTSASQIAADNGVGPTRIDDVVVVF
                     KAYPTRVGEGPFSTEMEREVSDRMGIREFGTVTHRQRRIGQWDGRMARYSAMVNGCTQ
                     AAITGIDRVDRDCFGITEYDRLTKKARDFLAQAEEDIGCPITLISTGPDVSQIIDIRG
                     EI"
     gene            complement(3769..4968)
                     /locus_tag="PK679_07385"
     CDS             complement(3769..4968)
                     /locus_tag="PK679_07385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HPC55816.1"
                     /translation="MRDFVSRKAREIPPSGIRRFFDLALTMDGVISLGVGEPDFSTPW
                     NICEASIYSIEQGGTSYTPNRGIKPLREALSRWLRDHYGLSCDPETEMIITTGVSEGL
                     DIAIRAIVDPGDEVLVAEPCYVSYSPCVTLAGGRPVPVPCVEKDRFRLNPDRLMEKIS
                     KKSKALIMNFPNNPTGAVMERADLKAVADIVCDHDLVLVSDEVYSELTYSGNHVAAAT
                     VGDLAPRTITLNGFSKAYAMTGWRIGYLCAPQEICDAALKIHQYVMLCAPVMGQVAAL
                     EGIRRGEEEKDRMVREYRVRRNLFVEGLNRIGLSCHRPEGAFYAFPSVTETGLSDQEF
                     AEGLLLEKHVAVVPGNVFGSGGEGHVRCAYAVSREDLARALQRMEEFVTGCKKKAIPL
                     VRSGHNP"
     gene            complement(4976..5467)
                     /locus_tag="PK679_07390"
     CDS             complement(4976..5467)
                     /locus_tag="PK679_07390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011842858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HPC55817.1"
                     /translation="MDERDLLLLQLLEENSRLTTQDLAVMTEMTPEEVSARVAALEAS
                     GVIRSYTAVIDWEKAGNGEVSAIIELKVNPERDYGYDRIAERIARFRQVRSLRLITGA
                     YDLQLTVTGRNMQEVARFVSEYIAPMDRIRETATHIIMKIYKENGRTFCEKEEGERIP
                     YSL"
     gene            complement(5475..6758)
                     /locus_tag="PK679_07395"
     CDS             complement(5475..6758)
                     /locus_tag="PK679_07395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014865901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORC1-type DNA replication protein"
                     /protein_id="HPC55818.1"
                     /translation="MSDDQSAAVGLFKKYLETNRIFKNREVLRHSYRPHILPHRQPQI
                     DQVAAILAPSLRNETPSNILIYGKTGTGKTAVVRYVGSELETAGGHMGMICRVVHLNC
                     EVIDTQYRVLAQISKTLLGEDQTASDKARTHIPMTGWPTDQVYAELKNQLEGMGGVLI
                     IVLDEIDKLVKKSGDETLYNLSRINSDLKKSKVSMIGISNDLSFKDFLDPRVLSSLSE
                     EELVFPPYNAPQLCDILKQRAEIAFLEGVLDESVIPLCAALAAQEHGDARRALDLLRV
                     SGEIADREEASRVTEAHVKMAQAKIETDSMIECIATLPTQSKVVLYAMLLLDQMGQTI
                     FTSGEVSRIYKEIAPSLDLDILTHRRITDLISELNMLGVINTRVVSRGRYGRTKEMWF
                     DTNTRKIWDVITSDARLSAQGIAERDVQWCRSLFR"
     gene            complement(6798..>6985)
                     /locus_tag="PK679_07400"
     CDS             complement(6798..>6985)
                     /locus_tag="PK679_07400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55819.1"
                     /translation="FSSGNNRVPPLKEISGTPVETNVFHVRLKFYKNRFFLTRPSYIT
                     LSSGNEGVYIRFKQLTF"
     assembly_gap    6986..7085
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            8033..8530
                     /locus_tag="PK679_07405"
     CDS             8033..8530
                     /locus_tag="PK679_07405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HPC55820.1"
                     /translation="MKKEHEKPVDIRAAVITVSTSRTRDTDGSGKAILSLLEGENIPV
                     LHYSLVKDDIVMIRRELHAVLDDCNCIIINGGTGISPDDCTIEAVVPVLDKIIDGFGE
                     IFRQKSYADIGTAAILSRALAGTCGERIIFCLPGSTPAVTLAMKEIILPELRHLVSHA
                     KRRDH"
     gene            complement(8779..9291)
                     /gene="cgi121"
                     /locus_tag="PK679_07410"
     CDS             complement(8779..9291)
                     /gene="cgi121"
                     /locus_tag="PK679_07410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex subunit Cgi121"
                     /protein_id="HPC55821.1"
                     /translation="METFFIRKVRVTIDDLDAFLQKINGIAARAGTHIIIFDAGRMAG
                     IAHVMSALRHAFRARDNGTMISARVEMEALLYAAGSRQIVEGTRFGIHAGENQAYLCL
                     CPENDAAWRELAPLFSPADDEDWETITPEKADLLCSLFSITAPELEVCGIGRLPDLVL
                     ERVALLEVYR"
     gene            complement(9292..11469)
                     /locus_tag="PK679_07415"
     CDS             complement(9292..11469)
                     /locus_tag="PK679_07415"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HPC55822.1"
                     /translation="MKVRDLPLPGYLQDIYANLGINDLYPPQAECVNKGLFEGKNILL
                     AVPTASGKTLVAEMAMHHHISRGGKCLYIVPLKALASEKYEDFARKQVRVGISTGDFD
                     RRDENLGRNDIIVATSEKVDSLIRNRAHWIPSITLLVVDEVHLIDEPHRGPTLEMVIT
                     KMRARNGNIQVIALSATIGNPGTLAGWLDAEVVTGSWRPVDLRQGVYCNGAISFGRET
                     RKVPPVSKNEDINLLLDTVAEGGQCLVFVASRRNAEAYARRAAAALKCTDPALEEYAA
                     RLKKAALTGNEESLASCVALGAAFHHAGLSRESRAIVEEGFRKGLIRCIASTPTLAAG
                     LNLPARRVIVRDFRRFEAGQGMVPIPAREYHQMAGRAGRPGLDPYGEAVLIARDTEEA
                     RELEEFYINASPEDVHSRCADESALITHILSLIASGFARTHDDLIRFLGRTFYHYQHK
                     KSSILEAVTKKSLDFLGKAEMITNLAGQLAATEYGNLVSLLYIDPRGAETIVSGIASA
                     ENYSDMGLLHLICSTPDMFCLYVSNRDLPVLERYLLENEDELWLTLGFGEEEPFFRAL
                     KTALVLRDWAGEVPIETICERYSIGPGDVHALVESCNWLLHAASRLSSLSAPRFTRAI
                     REFETCMKHGVRRELLPLVRLRNIGRVRARSLYSNGITSPDAIRAADPRVLASILGRG
                     IAQSVLQQLEQEGNGNGDNRTGDEGEENGLYGQSRLDAFHGVI"
     gene            complement(11619..12158)
                     /locus_tag="PK679_07420"
     CDS             complement(11619..12158)
                     /locus_tag="PK679_07420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012108035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HPC55823.1"
                     /translation="MIQELKVAQNRLGVLIGKGGQVKKDLEEKTETRISIDSQEGLVR
                     IEGESAVPFLRAVEVINAINRGFSPERAFSLLDDEDLLLEVIDLSGIADTPRQLDRLR
                     GRIIGRDGRAREQIEHMTNTQISVQGKTIALIGLPEQLKIARTAIDMLIEGAPHEAVF
                     SFLEKKRQESRQNMVDYYY"
     gene            complement(12155..12961)
                     /locus_tag="PK679_07425"
     CDS             complement(12155..12961)
                     /locus_tag="PK679_07425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012108034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protein kinase RIO"
                     /protein_id="HPC55824.1"
                     /translation="MSIDRIENRFDRKIAELGVRVRDMDQLKVREDVFDEITLLSLYR
                     LVHKGWITAIGGSISTGKEANVFFGERNEMDLAIKIYRIRTANFNAMSEYIIGDRRFA
                     GIRRTRKDIVFAWTRKEYSNLLRAHEAGLPVPRPLVWDRNILIMEFLGEDERPYPQLR
                     VAEMEDPVPAYSEILDDIRVLYQKAGLVHADLSEYNILAGDRLYIIDMGQAVMQDHPR
                     ALHFLVRDIANINRFFRSKCPLRDEREFFSEVTGIPLHGKAPGEGGNEKT"
     gene            complement(12977..13918)
                     /locus_tag="PK679_07430"
     CDS             complement(12977..13918)
                     /locus_tag="PK679_07430"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HPC55825.1"
                     /translation="MDAYALATRNTVEVVTTDELRELLKKDKKRVYAGYEPSGEIHLG
                     HLVTVNKLIDLQAAGFEVVVLLADLHAFLNRKGTMEEVRELADYNRRCFEGLGLSGVR
                     YVLGSDLQLDRDYELMVLRLSQQITLNRATRSMDEVGRQMDNPTVSQMIYPIMQMVDI
                     ARLGVEAAVGGIDQRKIHMLAREHLPSVGYPAPVCIHTPILNGLDGRKMSSSSHNYIS
                     VADSVENIEKKCQKAFCPPECEDNPILQILQYHIFPRVLRVEVRRPEKFGGDREFASY
                     AELEDAYRKGEIHPLDLKKTTARYLADILAGVRDHVS"
     gene            complement(14112..15134)
                     /locus_tag="PK679_07435"
     CDS             complement(14112..15134)
                     /locus_tag="PK679_07435"
                     /EC_number="1.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HPC55826.1"
                     /translation="MIKVAINGYGTIGKRVADAVAAQPDMKVVGVSKTRPSHEAFVAK
                     SRGYPLYIADLSRKDTFEKAGLPVAGSVEDMLKAADIVVDATPGGIGEKNKPLYERAG
                     VKAIWQGGEEHEVAGFSFNSDCNYTEAIGRQFARVVSCNTTGLCRIINAMDKNFGVEK
                     VRAVMVRRGGDPADIKRGPIDAIVLNPVHIPSHHGPDVRSVLPHINIVTLAMIVPVTM
                     MHMHVVQMDLKKAATREEVIRIIEKNPRMGLVRKATGITSTAELKEYAMDMGRPRSDL
                     WENGIFEDSISCTGKELYLFQAIHQEADVVVENIDCIRAMTGIEKDPAKSIAMTNQAL
                     KFVAIR"
     gene            15244..16185
                     /locus_tag="PK679_07440"
     CDS             15244..16185
                     /locus_tag="PK679_07440"
                     /inference="COORDINATES: protein motif:HMM:NF012933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HPC55827.1"
                     /translation="MALLIRPIAPYDFSLSCRVFSGGDPAFRTFHRGIFSQAIRVRGA
                     PVVIRIRDVGEDSDSVLAVDVFPGKEEYEYCAEDVGRCISHLLGLDDDLNSYYRATEA
                     DPVLARVNSALFGLKMPSSETLFEAFVTSIIEQQIATPVARKIEARLVKRFGEEVRAG
                     KRTYYAYPRPEDLADADPAEIRSCGLSARKGGYITSLACMVRDGALDLESLRGTGDSD
                     TLIRDLCRLKGIGRWTAEFVLLRGLHRLDSFPADDLGIRRAIGHLYCPGEEVSPARAR
                     EISRQWGEWKGLAAYYLLVADQHEMKSASQSRRDHTS"
     gene            16557..16832
                     /locus_tag="PK679_07445"
     CDS             16557..16832
                     /locus_tag="PK679_07445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2TM domain-containing protein"
                     /protein_id="HPC55828.1"
                     /translation="MTDERRERAMQRVGELKGFYSHLSGFLLINLLLVIINYVTSPGY
                     WWFYWITLAWGIALLFHAAHIFGRGKILTREWEEKKIQQYMDEEGKE"
     gene            complement(16836..17297)
                     /locus_tag="PK679_07450"
     CDS             complement(16836..17297)
                     /locus_tag="PK679_07450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC55829.1"
                     /translation="MEPPGKSAEILLVEDNPNDVELILHVFQWCNLSERVHVAWNGEE
                     ALDYVFGTGPYRERDINTQPNVILLDLKLPKVDGIEVLKRLKGDPKTRTIPVVVLTSS
                     REERDIVETYGLGVNSYIVKPVKFDDFANVIRELGLYWRMINQPPVRGDRE"
     gene            17485..19611
                     /locus_tag="PK679_07455"
     CDS             17485..19611
                     /locus_tag="PK679_07455"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55830.1"
                     /translation="MILDQEKIIRIKKLLKSRPKGLTISDISHTLKLNRNSVAKYLEI
                     LLITGEVEVRLYGNAKVYSLAQRVPISSILKFATELILILDSDFRIIDVNDNFLTFFS
                     LNKDDLMGSDIRTSPIPGIRAIFPGTIPGEDVFRAESKNEVNLCLSGKDYILAYKVVP
                     TVFDDGSRGYTLIFEDVTLSRDFEKKLKMSEERYRAIVEDQTEFICRFDPGFSFTFVN
                     GAVSKFFGKPAGEILGKNMLSFVHPDDRDRVRQNILSLAPGHDVMTHEHRVIDPSGET
                     RWHQWTNRAIIDSSGRIVEYQGVGRDITEKRIAEERLRILDMAVSSSINGIGIATLDG
                     RITYANAAFLRMFGISRPEDIIGQPIESLASSCTPEVGIREAMRELYEKGEWNGEVVI
                     HRKDGSPVYTHHTSNLVKDASGNPIATMASFIDITDKIEAEREIRIKNVAVESATNAI
                     MIFDTGENLIYANRVFLSLFGARNLRDMQENHMEDFWTVTRDFFPSIDEIRKEIIRTG
                     VWNGEVRIQKGEGSPRFFQVSMTLVRDDRGQPLCIIGVMMETSAQKVIEKALKTTYEK
                     LQEAVEFMPDPTFIIGREGKVIAWNRAMEVLTGVRSNEVIGSDRYGDALAFLQGTMPV
                     LVDILDLPAHELAKTWPSVRKFGDSIYAEATIPAHNDRKERLLWAKATPLFDGEGNII
                     GAIESFRDISEWKKAREFLPVRGSMQ"
BASE COUNT         4164 a         5537 c         5502 g         4358 t
ORIGIN      
        1 cgcaaccggg gcccggatga agtatgcccg gtatggccgc ccgagtcccc tgacactaat
       61 gtcagcctcg aatgactccc tctggcgccc gaacgcgttc ctctgcacag ccatgtcaat
      121 gaggccaaga ggcttcacgc gggggtcgtc cacccggtct gccacgagca ccattcccgc
      181 acacgtggca aagatgccgc cttcgaatcc ggcgaggggt tcgaataacc cattcttccc
      241 gatcaagcgg gaaatggtgg tggactcccc gcccggaatg gcaaggccgt ggagaccttc
      301 gagatcccct ggcttccgga cagggatgac agcccaatcg gcctccccca taaccctgag
      361 cgcccgttcg aaaccaagga tgtgctcgct cacgtcaccc tggagagcca gcaccccgag
      421 cctaacgccc acggtactgg agcacctcgt cctcgcggag ggtatggacg tcgatccctt
      481 tcatgggctg gccgagtccc ctgctcactt ctgcgatcac tttcgggtcg tcgtagtggt
      541 tcacggcctc gacgatggca cgggccatct tctccgggtt gcccgagtgg aaaatccccg
      601 accccacgaa gaccccgtct gcccccatct gcatcatcag ggcggcgtct gcaggtgttg
      661 caatcccacc cgcagagaag ttgacgacag gcaggcggcc catcttcacc gtctcgagga
      721 ggagatcggg cggtgcctcg agttcccgtg cccggctggt gatttcctgc ggtgtcttcc
      781 cctggagggc ccggatctcg cccatgatgt tgcgcatgtg gcggactgcc tccaccacgt
      841 tcccggtccc ggcctccccc ttcgtccgga tcatcgccgc gccctcgtgg atacggcgga
      901 gtgcctcgcc aaggtcgcgg gccccgcaca cgaaggggac agaaaacgcc ttcttgtcga
      961 tgtggtactc ctcgtcggca ggtgtgagca cctcgctctc gtcgatcatg tcaacgccga
     1021 gggactcgag gatctgggcc tcgacgaagt gcccgatgcg gacctttgcc atcacgggga
     1081 tcgagactgc gtccatgatc tcgaggatga tggcagggtc ggccatcctc gccacgccgc
     1141 ctgccttcct gatatccgcg gggacgcgct ccagcgccat gaccgcgacg gcacctgcat
     1201 cttccgcgat ccgggcctgc tctgcgttga ccacatccat gatcacccct cccttctgca
     1261 tggatgcaaa gccgcgtttc aggagttcgg tgccaaatct cagttcctcg agtttcatat
     1321 gtttatatga attggatgaa cagggccaaa aatattggta tcagcatgaa gagggcggca
     1381 cttgcgagag tgcaggcccg gacggctcca atgatatccc gtcccgcatc cgacaggctc
     1441 cgctcgcccg gaccgatcgt gtaggccccg ggcttgtcga accgggcacc gcacccgccc
     1501 gcaatcactg ccatgggaag cccgccattg aaacccgggc gtttctttgc atcctgccgg
     1561 aggcaccgta atgccggtgt ataccgtccc cgggctgcaa agtagaggag gaggattccg
     1621 gatgccaggc gggccgggac ataattcagg acatcgtcag cccgggccgg gaaccacccg
     1681 attcgttccc tctcgtcacg gtacccgagc attgcatcca tcgtgtttgc cgcccggtag
     1741 accgcggcac cggcaaggcc gaacagggca tagtagaaga ggggtgcaac gatgctgtcc
     1801 accaggttct cggagagcga ttcgtacgcg gctgaacgga cctggtccgc ggagagttcc
     1861 cgcgggtccc tgctcaccat gtagctgacc ttttcccttc cctccggcag gctggcggag
     1921 agggcccgtt ccaccgcatc cacgtgttcc tcgagtgaac gccaggcaag gcatactttc
     1981 aggaggacgg gtgcggcgac caggagggca taccatggca ggaaggcctc ggcgaggtag
     2041 aagggaaacg agaagagggc caccgttgca acccacatga ccacgccggc agcccgttgc
     2101 agtgacggcc ggattttccg cggatcgccc cagaacgcga tgaactgccc cacgagtgcg
     2161 acagggtgga aacgggaacg ggggtctcct gtcaccctgt cgacgaggag ggagagggga
     2221 atgactgcaa ggcgtgcgat gagcatggtt ggggacaggc ggggttatta ccggggtgga
     2281 ggcaggtgcg ccgggcatgg tgcgtcatcc caacgcggaa tctgcccttt tattctttcc
     2341 aggctttcct gctcaggttt ttgacttttt ttcccggggg agcaggtcgg ggataccctc
     2401 ctcaatcggg taatccaccc cgcaggccgg gcactggagt accccctcta taatctcctt
     2461 ttcgtcctcg agtgtcaccc ggagtgtgag atcccccttg cagacgggac agcagaggat
     2521 gggcaggagg gagcgcttca tatctcgccc ctgatgtcga tgatctgcga gacgtccggc
     2581 cccgtcgaga tgagggtaat ggggcatcca atatcctctt ctgcctgggc aaggaaatca
     2641 cgggcttttt tcgtcagccg atcgtactct gttattccaa aacagtccct gtcaacccgg
     2701 tcgatccccg tgatcgcggc ctgggtgcag ccgttcacca tggcagaata ccgcgccatc
     2761 cttccgtccc actggcctat tctcctctgc ctgtgcgtga cggtaccaaa ttcccggatg
     2821 cccatgcggt ctgagacctc cctttccatt tcagtcgaga acggcccctc gccgaccctt
     2881 gtcggatagg ccttgaagac gaccacgaca tcatcgatgc gtgtcggtcc caccccgtta
     2941 tcggccgcta tctgggacgc tgacgtatcc ttgctcgtca catacgggta ggtcccataa
     3001 tagagcgata tcccgaatcc ctgtgtccct tcaaggagaa tgtgttcgcc ccggtcaaga
     3061 gctgaattga tctcgagggg cacatctgca atgtagtcac cgagctcggg gatgtccctt
     3121 gccagcctcg ccacgcggag gacgcggtct gcgtttgcag ggccgcaccc gctccccgtg
     3181 ctcccgattg tctttgcgag gtgggaactt gacctgtccc tctcgatgtg accttcatcg
     3241 atgatggcac accggtagtc gacgaatatc cttcccccga ccccgagcat ctcgacttcg
     3301 cgggcaaaga ccctcgggtc caccaggaca ccggttccaa tcatgaggcg ggcatgggga
     3361 tatacgaacc ccgatgggac catgcgcaca ccgtactcct tctctcccat ctttaccgtg
     3421 tggccggcat tcggaccgac ccctccccgg gagatgatgg aggggtggtc ctggtaggca
     3481 aggtgtgcaa cgatcttgcc cttcccttca tcaccaaaaa aaccgcccac gactatggtg
     3541 caactcatgg tacaaccata tactatacat ccggataccg gataaaagac tatcgtggga
     3601 gacgtgcccg tgccctcatg cgggtgaagt gcaggatggt tttccggact gtcggacgga
     3661 tgtgcaggga tacccgcaag ggatccctgt ccgacactgt tcccacacct tcgcaaggcg
     3721 gggtatcagg acctgcaaaa aactgatggg aaagggacgc ctgcccggtt agggattgtg
     3781 accggaccgg acaagcggga ttgccttctt tttgcaaccc gtgacaaact cttccatccg
     3841 ctgcagagcc cgcgcgagat cctcccgcga gaccgcgtag gcacaccgga cgtgcccttc
     3901 cccaccgctc ccaaagacgt tgcccggaac gacggccacg tgtttctcga ggagaagtcc
     3961 ctcggcaaat tcctggtctg aaagtcctgt ttctgtaacg gaggggaacg cgtagaaggc
     4021 accctcggga cggtgacagg aaagcccaat ccggttcagc ccctcgacga agaggttgcg
     4081 gcgcacgcgg tattccctga ccatcctgtc cttttcctcc tcgcccctcc gtatcccctc
     4141 gagggccgcg acctggccca tgaccggggc acagagcatc acatactggt gaatcttgag
     4201 ggctgcatcg cagatctcct gcggtgcaca gaggtacccg atccgccacc ccgtcattgc
     4261 ataagccttc gaaaaaccgt tcagggttat cgtgcgcggg gcaaggtcac ccacggttgc
     4321 ggccgcgacg tggttcccgc tgtaggtcag ttccgagtat acctcgtcgc tcaccagcac
     4381 caggtcatgg tcacagacga tatcggcaac tgccttgagg tctgccctct ccatgactgc
     4441 ccccgtcggg ttgttcggga agttcatgat gagtgccttg ctctttttcg agattttctc
     4501 catcagcctg tcgggattga gcctgaacct gtccttctcg acacagggga cggggaccgg
     4561 tcttcctccc gccagtgtca cgcagggaga gtaggagaca tagcagggct ctgcaacgag
     4621 gacctcgtcc cccggatcga caattgcccg tatcgcaatg tcaaggccct cggaaacacc
     4681 ggtggtgatg atcatctcgg tttcaggatc gcaggagagc ccgtaatggt cgcggagcca
     4741 gcgggacagt gcctcccgga gaggtttgat ccccctgttc ggcgtgtagg atgttcctcc
     4801 ctgctcgatg gagtaaatac ttgcctcgca gatgttccag ggcgttgaaa agtccggttc
     4861 ccccacgccg agcgagatga ccccgtccat ggtgagggcg aggtcaaaga acctgcggat
     4921 gccggaaggg ggaatctccc ttgccttccg ggagacaaag tccctcatcg taacctcaca
     4981 gcgagtacgg gatacgttcg ccctcttcct tttcgcagaa ggtgcgaccg ttctccttgt
     5041 agatcttcat gatgatgtgg gttgcagtct cccgtatcct gtccatcggg gcgatgtact
     5101 cggacacgaa ccgtgcaacc tcctgcatgt tcctgcccgt gacggtgagc tggaggtcgt
     5161 acgcccccgt gatgagccgg agggacctga cctggcggaa cctggctatc ctctcggcga
     5221 tccggtcgta tccatagtcc cgctcggggt tcaccttcag ctcgatgatt gcagacacct
     5281 cgccgtttcc tgccttctcc cagtcgataa ctgcagtata gcttcggatc acgcctgagg
     5341 cttccagtgc cgccacccgt gctgaaacct cttccggcgt catctctgtc atgactgcca
     5401 gatcctgcgt ggtcaggcgg ctgttctcct cgaggagctg gagcaggaga aggtctcttt
     5461 catccatgac tgtttcacct gaaaagggat ctgcaccact ggacgtccct ctcggcgata
     5521 ccctgggcac ttaagcgggc atccgaagtg atcacatccc atatcttacg tgtattcgta
     5581 tcaaaccaca tctcttttgt cctgccatag cgaccccggc tcaccacgcg ggtgttgatg
     5641 accccgagca tgttcagctc ggaaatgagg tccgtgatcc tccggtgcgt gaggatatcg
     5701 aggtcaagag agggtgcaat ctccttgtag atcctgctca cctccccgct cgtgaagatg
     5761 gtctggccca tctggtcgag gaggagcatg gcgtagagga cgaccttgct ctgggtgggc
     5821 agtgtcgcga tacactcaat catcgagtcc gtctcgatct ttgcctgggc catcttcacg
     5881 tgagcctccg tgactcggct ggcctcttcc ctgtcggcaa tctctcccga tacgcggaga
     5941 aggtcgaggg cccggcgcgc atccccgtgt tcctgggccg cgagcgccgc gcacagcggt
     6001 attacactct cgtcgaggac tccctcgagg aaggctatct ctgcgcgctg cttcaggata
     6061 tcacagagct ggggggcatt gtagggcggg aagacgagtt cctcttcgga gagggaggac
     6121 aggacccttg ggtcgaggaa gtccttgaag gagaggtcat tcgagatccc gatcatgctc
     6181 actttggatt ttttcaggtc ggagttgata cgggagagat tgtagagggt ttcgtcaccg
     6241 ctcttcttga cgagtttgtc tatctcgtcg agaacgatga tgaggactcc tcccataccc
     6301 tcgagctggt tcttgagttc ggcatagacc tggtcagtcg gccaccccgt catggggatg
     6361 tgggtccggg ccttgtcgct tgccgtttgg tcctcgccaa ggagcgtctt tgaaatctgc
     6421 gcgagaacac ggtactgggt gtcgatcacc tcacagttga ggtgcacgac cctgcaaatc
     6481 atccccatgt ggccccctgc cgtctcgagt tccgacccca cgtaacggac gaccgctgtc
     6541 ttccccgtcc ccgttttgcc gtagatgagg atattcgagg gggtctcgtt ccggagggag
     6601 ggtgcaagga ttgctgcgac ctggtctatc tgaggctgcc tgtggggaag gatgtgtggc
     6661 ctgtaggaat ggcgcaggac ttccctgttc ttgaatatcc tgtttgtctc cagatatttt
     6721 ttgaaaagcc cgactgctgc actctggtcg tctgacatcc ctgaccccct gggagataat
     6781 catatccctg ccaatactca aaaagtcagc tgtttgaacc tgatataaac cccttcattt
     6841 ccactggaga gagttatata agagggtctt gtgagaaaaa atcgattttt ataaaatttt
     6901 agtctgacgt gaaaaacgtt tgtttccaca ggagtcccgg atatttcttt caaggggggg
     6961 accctgttat ttccactgga aaatgnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7081 nnnnnggagt cccggatatt tctttcaagg gggggaccct gttatttcca ctggaaaatg
     7141 gatgtgaact tcataatatg aagttgattt tacaggagaa caagtcattt aatgttccac
     7201 ttttctttta taaaatctta atgaaatgat tcggaactca atggggatat acatgaaaca
     7261 ccccgtgact ctatagtgat gtgataaaaa aagtcaagga aaaagtgatc gcatcttcat
     7321 tctccagtgg aaacaaaggg gttccccaga attgaaacat ggatagatat cacagagtcc
     7381 aaaaaaatct ataaatattg taggaaatct cacttgaata gagataccat gtaaaaatat
     7441 agaatctttg atttcgacct tttcactatc cggccttttg atggactggc acctgaataa
     7501 tcttcatgaa gtgcttatta aacgaaaata atgacccaac gcactctgtt ggcattctgt
     7561 cttctctctt cgaagagaaa cctctatttg cgccttggag tgacctgatg agatcctggt
     7621 aaactatttt ctttgtggta acattgttac agaaaaatgc ggtgctccgg gacattctcc
     7681 cttatatgtg ctgatttgga gagggtgcag gtcctccagg gtggaccgct tcatctgact
     7741 ccctgtatgt atagggtttt atgggaaggc acctcggaca ggtgactccc cccattggta
     7801 cccttatcta taaagcttgg aggggaggct tgtcccggag aaaaaccccc gcactctcgc
     7861 ctgaacaggt tccatgttgg acatctacgg tatcctgtca gaaaaaacat cacaggcacc
     7921 ttccaatctc cagtggaaat aagagggtct gttcctgtcc tcaatcgtgg tcgaaaaacc
     7981 gttcagcaca gaggaaaatt gttaatcttt cgaagaaacg aatcaggtaa cgatgaaaaa
     8041 agaacacgaa aaacccgtgg acatcagggc ggcagtgatc accgtgtcca cctcgcggac
     8101 cagggataca gacgggagtg gaaaagctat cctatccctc ctggaagggg aaaatatacc
     8161 cgttctccat tattctctcg tcaaagatga tatcgtgatg atcaggagag agctccatgc
     8221 ggtgctcgat gactgcaatt gcatcatcat caacggggga acggggatct cgcccgatga
     8281 ctgtaccatt gaagcggtgg ttcccgttct ggacaagata atcgatggat ttggagagat
     8341 attcaggcag aaaagttatg cagatatcgg cacggcagca attttatcga gagccctcgc
     8401 cgggacatgt ggggagagaa ttatcttctg ccttccgggg tcgacgccgg cagtgacact
     8461 tgccatgaaa gagatcattc ttccggaatt acgccacctc gtgtcgcatg caaaaaggag
     8521 agatcattga tttcacgagg gtccggcatc gccagttccg aatcttgccc ctataatttc
     8581 cggaatcttt tttccggtca cttttttccc tctccatgga taccccatga accttgtaaa
     8641 aaaatcgctc catggacgat tcctgacccc atcgtgttgt cttgtggtcc tgaatcaggc
     8701 aggattagtg cgggaaaaca gggcagataa tgaaaaagaa ggataggttt acccactcct
     8761 ccggccggca tacctctttt accggtatac ttcgaggagt gccaccctct ccaacacaag
     8821 gtccggcaaa cgcccgatcc cgcagacttc gagctcaggt gcggtaatgg agaagagcga
     8881 acagagaagg tctgctttct ccggagtaat ggtctcccag tcctcgtcat cggcaggaga
     8941 aaaaaggggt gcaagttccc tccatgccgc atcgttctcc gggcagaggc agaggtatgc
     9001 ctggttctca cccgcgtgaa taccaaaccg cgttccctcc acgatctgtc gtgatcctgc
     9061 ggcatagagg agggcctcca tttccactct cgccgagatc atcgtgccgt tgtcccgtgc
     9121 cctgaaggca tggcggaggg cagacatgac atgggctatt ccggccatcc tgcctgcatc
     9181 gaagataatg atatgtgtcc ctgccctcgc tgcgataccg ttgatctttt ggaggaacgc
     9241 atccaggtca tcgattgtga cccttacctt ccgaataaag aacgtctcca ttcagattac
     9301 cccgtggaag gcgtcgagtc gcgactggcc gtaaagacca ttctcttccc cttcgtcccc
     9361 tgtgcgattg tctccgttcc cgttaccttc ctgttccagc tgctgcagga cagactgggc
     9421 aatcccgcgg ccgaggatgg atgcaagcac cctcggatcg gcagcacgaa tggcgtccgg
     9481 agacgttatc ccgttggaat agaggctcct tgcccgtacc cggccgatat tgcgcagcct
     9541 gacgagtggc agcagttccc gcctgacacc atgtttcatg caggtctcga actcgcggat
     9601 tgcccgggtg aagcggggcg cacttaacga cgaaaggcgg ctcgcggcat ggaggagcca
     9661 gttgcagctc tcgacgaggg catggacatc tcccggcccg atggagtacc tctcgcaaat
     9721 ggtctcgatg gggacttcgc ccgcccagtc ccggaggacg agggcggtct tgagggcacg
     9781 gaagaaaggc tcctcctcgc caaagcccag tgtcagccag agttcatcct cgttctcgag
     9841 caggtacctc tccagcacgg ggaggtccct gttgctgaca tacaggcaga acatgtccgg
     9901 tgtgctgcag atgaggtgga ggaggcccat atccgagtag ttttctgccg aagcaatccc
     9961 cgagacgatg gtctctgcac ctcgcgggtc tatgtagagg agggagacca ggtttccgta
    10021 ctctgttgca gccagctgac cggcaaggtt cgtgatcatt tccgccttcc cgaggaaatc
    10081 aagtgacttt ttcgtgacag cctccagaat gctgctcttc ttgtgctggt aatggtaaaa
    10141 tgtccgcccc agaaaccgga ttaagtcatc gtgggtccgg gcaaatccgg atgcaatcag
    10201 tgacaggata tgtgttatca gcgcggactc gtcagcgcac cgggagtgca catcctcggg
    10261 agaggcatta atgtagaatt cttcaagttc ccgtgcctcc tctgtatccc ttgcgatgag
    10321 caccgcctcc ccgtaaggat caagacccgg tctccctgcc cggcctgcca tctggtggta
    10381 ctcgcgggcc gggatgggga ccattccctg cccggcctcg aaccggcgga aatcccggac
    10441 aatgacccgc cgggcaggga gattcaaccc ggcagccaga gtcggggtgg aagcgatgca
    10501 ccggatcagg cccttcctga acccctcttc cacgattgcc cgggactccc gggagagccc
    10561 ggcatggtga aacgccgcac ccagggcaac gcaggaggca agggactcct cgttgccggt
    10621 cagggcggcc ttcttcaagc gggcagcgta ctcttcgaga gccgggtccg tgcatttgag
    10681 tgctgctgcc gccctcctcg catatgcctc ggcattcctg cgcgacgcga cgaagacaag
    10741 gcactgcccg ccctccgcaa ccgtgtcgag aaggaggttg atatcctcgt tcttcgaaac
    10801 ggggggcact ttccgggttt cccggccaaa agagatcgca ccattgcaat agaccccctg
    10861 gcggaggtcg accgggcgcc acgaccctgt caccacctcg gcatcgagcc atcctgcaag
    10921 tgtacccggg tttcctatcg tcgcggaaag ggcgataacc tggatgttcc cgtttcttgc
    10981 ccgcatcttc gtgataacca tctcgagcgt cggccccctg tggggttcgt cgataaggtg
    11041 cacctcgtcc acgacgagga gcgtgattga cggtatccag tgtgcacggt tgcgtatcag
    11101 cgagtcaacc ttctcgctcg tggccacgat gatgtcattc cgcccgaggt tttcgtcacg
    11161 tctgtcgaag tcaccggttg aaatacctac cctgacctgt ttccgggcaa agtcctcgta
    11221 cttctcgctt gccagggcct tgagggggac gatgtagagg cacttcccac cccgggagat
    11281 atggtggtgc atggccatct cggcgaccag cgtctttccg cttgcagtgg ggactgcgag
    11341 gagaatgttc tttccctcga agagtccttt attgacgcac tctgcctggg gaggatagag
    11401 gtcattgatg ccaaggttgg catagatgtc ctgaaggtat cccggaagag ggagatctct
    11461 taccttcatt tataacccct ttatttccac tccacagagc tcattataat ccgatctcaa
    11521 taaaaaccag gccatcgtcc ggtattcacc tgcactggaa ataatgcctt acaggctttt
    11581 gtacgtcatg cgggtagcat ccatagccca tgcacggttc agtagtaata atcgaccatg
    11641 ttctgccgcg attcctgtct cttcttctcg aggaaggaga agactgcctc gtggggggcg
    11701 ccctcgatca gcatgtcaat ggcggtccgg gcaattttga gctgttcagg caggccgatg
    11761 agagcgattg tctttccctg aaccgagatc tgggtgtttg tcatgtgttc gatctgctcc
    11821 cgtgccctgc cgtcccggcc gatgatccgt cccctgagcc ggtccagctg tcgcggagtg
    11881 tcagcaatcc ccgaaaggtc aatcacctcg aggaggaggt cctcatcatc gagaagggaa
    11941 aaggcccgtt cgggtgaaaa accccggttt atggcattga tgacttcgac tgcccggagg
    12001 aaaggtactg cggattctcc ttcgatcctg accaaccctt cctggctgtc gatacttatc
    12061 ctggtttctg tcttctcttc caggtccttc tttacctggc cgcccttccc aatcaggaca
    12121 cccagtcggt tctgggctac tttcagttcc tgtatcatgt cttttcattc cccccttcac
    12181 caggggcttt cccgtggagc ggaattccgg tcacttccga aaagaattcc ctttcatcac
    12241 ggagagggca ctttgaccgg aaaaacctgt tgatgttggc gatgtcccgg acaaggaagt
    12301 ggagtgcccg ggggtgatcc tgcatgaccg cctgccccat gtcgatgata tagaggcggt
    12361 cacctgcgag gatgttgtat tccgaaagat cggcatggac aaggccggcc ttctggtaga
    12421 gtaccctgat atcgtcgagg atttcgctgt atgcagggac cgggtcctcc atttcagcga
    12481 cgcggagctg gggatacggg cgttcatcct ccccgaggaa ctccatgatg agaatgtttc
    12541 ggtcccagac aagaggcctt gggacaggaa gacccgcctc gtgggcacgc aggagattgg
    12601 aatattcctt ccgcgtccat gcaaagacga tgtccttgcg ggtcctccgg attcctgcaa
    12661 accgccggtc accgatgata tactcgctca tggcattgaa gttggccgtc cggatccggt
    12721 agatcttgat ggcgaggtcc atctcgttcc gttcaccgaa aaaaacgttc gcttccttcc
    12781 ccgtcgagat cgatcccccg atagcggtaa tccagccctt gtggacgagg cggtacaggg
    12841 aaaggagagt gatctcgtca aagacgtctt cccgcacctt gagctggtcc atgtcccgga
    12901 cgcggacccc gagttccgca atcttccggt cgaacctgtt ctcgatgcgg tcgatgctca
    12961 cgtgatactc acccgttcat gaaacgtggt ccctgactcc tgcgaggata tccgcgaggt
    13021 accgggcagt cgtcttcttg aggtcgaggg ggtgtatttc ccccttcctg tacgcgtcct
    13081 cgagctcggc gtagctggca aactcacggt cgccgccgaa cttttcgggc cggcgcacct
    13141 cgacccggag tacgcgtggg aagatatggt actggaggat ctggagtatg gggttgtcct
    13201 cgcactccgg gggacagaac gctttctggc acttcttctc gatattttcg acgctgtctg
    13261 caacggatat gtaattgtgg cttgaggaag acatcttcct gccgtcgagg ccgttgagta
    13321 tcggcgtatg gatgcagacg ggtgccgggt aaccgacgga ggggaggtgt tccctcgcga
    13381 gcatgtggat cttcctctgg tctatgcccc cgactgcagc ctcgacaccg agccgtgcaa
    13441 tgtccaccat ctgcatgatc gggtagatca tctgggagac ggtgggattg tccatctgcc
    13501 tccccacttc gtccatgctc cgggtggccc tgttcagcgt gatctgctgc gaaagccgga
    13561 gcaccatcag ttcgtagtcc ctgtcaagct gcaggtcaga cccgaggacg tacctgacac
    13621 cggaaagacc gagcccctcg aaacaccgcc tgttgtaatc ggccagttcc cggacttctt
    13681 ccatcgttcc tttcctgttc aggaatgcat ggaggtcagc gagcaggacg acgacctcga
    13741 acccggccgc ctggaggtcg ataagcttgt tgactgtcac gaggtgaccg agatggatct
    13801 cgccgctcgg ttcatacccg gcatataccc tctttttatc ctttttgagg agttcgcgga
    13861 gctcgtcggt cgtgacgact tcaaccgtgt tcctcgtcgc aagagcatac gcatccattc
    13921 gtacaaaatg gggaatgcag ggtgttaatg cttgtgtggg tgcctgcccc cgtgcaaaaa
    13981 acctgttgaa tgcacatggg ggcaatccgg cggaaccagc cggtaaccgg ggtggtcatg
    14041 cactctgtct ctctctgcag gttacgaaaa tgcgctgccg gcctcaacca tgacagcgga
    14101 aaaaagggtg gttacctgat tgcaacaaat ttcaatgcct ggtttgtcat ggcgatggat
    14161 tttgcagggt ccttctcgat tcctgtcatt gcccggatgc agtcgatgtt ctcgacgaca
    14221 acgtctgcct cctggtgaat cgcctggaaa aggtagagtt ctttgcccgt gcaggagatc
    14281 gagtcctcga agataccgtt ttcccagagg tccgagcggg gccgtcccat gtccattgca
    14341 tattccttca gctcggccgt gctcgtgatc ccggtggcct tccggacaag ccccatgcgg
    14401 ggattcttct cgatgatcct gatgacttcc tcacgcgtgg ccgccttttt caggtccatc
    14461 tggacaacat gcatgtgcat catcgtcacc gggacgatca tcgcgagcgt cacgatgttg
    14521 atgtggggca ggacactccg gacgtccggc ccgtggtgac tcgggatgtg gacggggttt
    14581 aacacgatgg catcgatcgg cccccgcttg atatcggcag ggtccccgcc ccgccggacc
    14641 atcaccgccc ggaccttttc aacgccaaaa tttttgtcca ttgcgttgat gatgcggcac
    14701 agtcccgtgg tgttgcagga gacaacccgt gcaaactgtc tcccgatggc ctcggtataa
    14761 ttgcagtcgg aattgaagga gaatccggca acctcgtgct cctctccacc ctgccagatg
    14821 gccttcacac cggctctctc gtagagtggc ttgtttttct ccccgatacc gcccggcgtt
    14881 gcatccacca cgatatctgc agctttcagc atgtcctcga cgctccctgc gacaggcaga
    14941 ccggccttct cgaaggtatc cttcctggag agatcggcga tatagagcgg gtaacccctg
    15001 gactttgcca cgaacgcctc gtggcttggt ctcgtcttgg atacccccac cactttcatg
    15061 tcgggctggg cagccactgc atcggcaacg cgctttccaa tcgtcccgta cccgttgatg
    15121 gcaactttga tcatatggtg agggagtggg aatgaggggc attaaaggtt gccaaatgtg
    15181 aggaaaaggt gaaggaaaat accaccattc ttttctcctg tcccatccat tggattaccc
    15241 ggaatggccc tcctcatccg cccgattgcc ccgtatgact tctccctcag ttgcagggtc
    15301 ttttccgggg gagacccggc attcaggact tttcacagag gtatcttctc gcaggccatc
    15361 cgggtcaggg gcgcaccggt tgtcatccgt atccgggatg taggggagga cagcgattcg
    15421 gtccttgccg tcgatgtctt tcccgggaaa gaagagtatg agtattgcgc agaagacgtg
    15481 gggagatgca tctcccacct gctgggcctt gacgatgact tgaacagcta ttaccgggca
    15541 acggaggcag accccgttct tgcccgtgtc aactcggcac tattcggctt aaaaatgccc
    15601 tcgtcagaga cactctttga ggcattcgtg acctcgatca tcgagcagca gattgcgaca
    15661 ccggttgcac gcaagatcga ggcccgactg gtgaagcggt tcggagagga agtgagggct
    15721 ggcaaaagga cgtactacgc gtatccccgc cctgaagatc tcgccgatgc cgatccggct
    15781 gaaatccgga gttgcgggct ttctgcccgg aagggcggat atattacatc tcttgcgtgc
    15841 atggtgaggg acggggcact tgatctcgaa tcgctcagag gcacaggcga ttcagacacc
    15901 ctgatccggg atctgtgccg gctgaagggg atcggacggt ggacagcgga gttcgtgctg
    15961 ctccgggggc tccatcgtct ggactcgttc cctgcagatg atctggggat aaggcgtgcg
    16021 attggccatc tttactgtcc gggggaggaa gtcagcccgg cacgggcaag ggagatctcc
    16081 cggcagtggg gggaatggaa ggggcttgca gcatactacc tcctcgtcgc agaccagcac
    16141 gaaatgaaga gtgcatcgca aagccgaagg gatcatacgt catgaacgtt ctcctctccg
    16201 ttttgaagag ggagagccgc cggggtagcg agggcgggaa gaagggcgaa ggaaaaaatc
    16261 atacgtcact gcctttcccg tggtcgcaga gaaaggagga gtgcaggcac tggctgcaca
    16321 gaaaactcac gggaagggca tatcggggtt tttccacggg acataccaga cactcatctc
    16381 catgaggcag caggagtagg gtaagacgat tgatgacttg cacaactcca acggctggca
    16441 ggaggcaggg aatatttcca tttttgtctt cggaagagca atgactgatc cgggggtcat
    16501 gggataaaat tgaagacgag gcattgataa aaagtacagg aaggacggaa aaaaggatga
    16561 ccgatgagag aagggagcgg gcaatgcagc gggttggaga actcaaggga ttctattccc
    16621 acctgtcagg tttcctgctc atcaacctgc tcctggtaat cataaactac gtcacctcgc
    16681 ccggttactg gtggttttac tggataacac tggcatgggg aattgcactt cttttccatg
    16741 ccgcacacat ctttggaagg ggaaaaatac tgacaaggga atgggaagaa aaaaagatac
    16801 agcagtacat ggacgaagaa gggaaagagt aatacctact ccctgtctcc cctgactggc
    16861 ggctggttga tcatcctcca gtagagtcca agttcccgga tgacatttgc aaaatcatca
    16921 aatttcaccg gttttacgat gtagctgttc accccgaggc cataggtctc cacgatatcc
    16981 cgctcttccc gggaggatgt cagcaccaca acgggaatgg tccgggtttt cgggtcacct
    17041 ttcaggcgtt tgaggacctc gataccgtcg accttgggga gtttgaggtc aaggaggatg
    17101 acgtttggct gggtattgat gtctctctcc ctgtagggac ctgttccaaa cacataatcg
    17161 agggcctctt caccgttcca cgcaacatgg accctttcag aaaggttaca ccactggaaa
    17221 acatggagga tgagctcgac atcattggga ttgtcctcga caaggagaat ctcggcactc
    17281 ttcccagggg gctccattga taagcatgaa ccacaggtaa cgaaatattt tttgtgtcac
    17341 aaggcccctg cccgaagggc ccggtcgcat ggaaaggacc gtctttgaaa ggtgttgtac
    17401 taccggtcgg gacacccctt cgtgaggggg agccatctga atggcatatc tttatggcag
    17461 ggtggacgag atcaaccatc agtcatgatt ctggaccagg aaaaaatcat aaggataaaa
    17521 aaattgctga aaagcaggcc caaaggcctc accatttcgg atatttccca taccctgaag
    17581 ttaaaccgga attctgtcgc aaagtacctg gagatcctcc tcatcacggg cgaggtcgag
    17641 gtccggctct atggcaatgc caaggtctat tcccttgccc agcgggtacc catctcctct
    17701 atcctcaagt ttgcaacgga actcatcctc atactcgatt cggatttccg gattattgat
    17761 gtcaacgata acttcctcac ttttttctcg ctcaataagg acgacctgat gggaagtgac
    17821 ataaggactt ctccgatccc gggaatcagg gcgatcttcc cggggacaat ccccggcgag
    17881 gacgtcttcc gtgcggaaag caaaaatgag gtgaacctgt gcctttccgg gaaagactac
    17941 atccttgcat acaaggtcgt ccccaccgtc tttgacgacg ggagcagggg atataccctc
    18001 attttcgagg acgtaaccct ttcccgcgac ttcgagaaga aactgaagat gagcgaggag
    18061 aggtaccggg caatcgtcga ggaccagacg gagttcatct gcaggttcga tccgggtttt
    18121 tccttcacct ttgtcaatgg tgctgtgagc aagttcttcg ggaaacccgc cggggagatt
    18181 cttgggaaaa acatgctttc gtttgtccat cccgacgaca gggacagggt caggcaaaac
    18241 atcctctccc ttgcgcccgg tcacgatgtg atgacccatg aacacagggt tattgacccg
    18301 tcgggggaaa ccaggtggca ccagtggacg aaccgggcga tcatagattc ttcggggagg
    18361 attgttgagt accagggcgt cggaagggat atcaccgaga agagaattgc cgaggagaga
    18421 ctccggattc tggatatggc cgtatcgtcc tccatcaatg gcattggcat tgccaccctt
    18481 gacggtcgca taacgtatgc aaacgcggca tttctcagga tgtttggaat ttcccgtcct
    18541 gaggacatca tcgggcagcc catcgaatcc cttgcctcgt catgtacgcc cgaagtcggg
    18601 ataagggaag caatgaggga actctacgag aagggagagt ggaacggcga ggtcgtgatc
    18661 caccggaaag acggaagccc tgtctatacc caccacacgt caaacctcgt taaggacgct
    18721 tccggaaacc ctatcgcaac catggcctcc tttattgata taaccgacaa gatcgaagcg
    18781 gaaagggaaa tccgcatcaa aaatgttgca gtcgagtctg caacgaatgc cattatgatt
    18841 tttgatacgg gtgaaaacct gatctatgca aaccgggtct tcctttccct gttcggggca
    18901 aggaacctcc gcgacatgca ggagaaccac atggaagact tctggacggt tacccgtgac
    18961 ttcttcccgt ccattgacga aatcaggaaa gaaatcatac ggaccggggt atggaacgga
    19021 gaagtccgga ttcagaaagg agagggatct ccccggtttt tccaggtctc gatgactctc
    19081 gtcagagatg acagggggca gcccctctgc atcatcggtg tcatgatgga aacatcggcc
    19141 cagaaggtta tagaaaaggc gctcaagacg acgtacgaga aactccagga agccgttgag
    19201 ttcatgcctg acccgacatt catcatcggc agggagggga aggtgattgc atggaacagg
    19261 gccatggagg tactgacagg agtcaggagt aacgaggtca tcggttctga caggtatgga
    19321 gatgccctgg cattcctgca gggaacaatg cctgtcctcg ttgatatcct ggacctccct
    19381 gcacacgagc ttgcaaaaac ctggccgtcg gtcaggaagt tcggtgacag catctatgcc
    19441 gaagcgacca ttcctgcgca caacgacagg aaagagaggc tcctctgggc caaggcgaca
    19501 cctctctttg acggggaagg aaacatcatc ggggcaatcg agtcgttcag ggacatttca
    19561 gaatggaaaa aggcacggga atttctcccg gtcaggggct cgatgcagta gaaaataccg
    19621 ttcgggaaca aggctttcgg gtatcgggag agaagggccg g
//
LOCUS       DAOOJU010000030        18811 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_2900_length_18811_cov_15.774579, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000030 DAOOJU010000000
VERSION     DAOOJU010000030.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 18811)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 18811)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18811
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2900_length_18811_cov_15.774579"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..790
                     /locus_tag="PK679_07460"
     CDS             <1..790
                     /locus_tag="PK679_07460"
                     /inference="COORDINATES: protein motif:HMM:NF019500.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HPC55831.1"
                     /translation="VIVFALVLFAGIAGFSLLEGFSPFDSLYLTIVTVATVGYGDLHP
                     VTPAGKALAVAVIVGGVGCFVGLVTNAVEHLAYRAERERRRRKTGILVGLFFSQLGTS
                     LLASFSWLDPERKDLARVLSDPGSFSGDRLRTLAADLGGRRYALDSRNCDLVALREAL
                     GRKVDVLSMLLQNPDLDEHSRFSDLLQALLHLWQELVHREDLSELPDTDYDHLSGDIS
                     RVYGLLVVEWIVYMGHLRLTYPYLYSLALRTNPFDETASVIVRD"
     gene            869..2194
                     /locus_tag="PK679_07465"
     CDS             869..2194
                     /locus_tag="PK679_07465"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HPC55832.1"
                     /translation="MKTISFADLDVPEPLLRAIRDLGFEEPTPIQSLAIPVIREGHDM
                     VGQAHTGTGKTAAFGIPLLEMLEPDRPAVQALVLCPTRELAIQVSEELRKLARYMGGV
                     SVLPVYGGQPIERQVAVLRKGVHVVIATPGRLLDHLSRRTVDLSQVRVTVLDEADEML
                     DMGFAEDIAKIFTRLPEKRQNVLFSATMSREILALAQKFLKDPRMVRVVHGQLAVPVI
                     EQRYFEVRESEKVEVLSRLLDYYNPDLALVFCNTKRRVDEVASQLQARGYLAESLHGD
                     MDQKERERVMSRFRSRSTDILVATDVAARGIDVEEIGIVFNFDVPQDPEYYIHRIGRT
                     GRAGKSGKAFTFVSGKEMWKLRDIQKYARIRIARHAVPADADLEERRFVHIGEKVRDV
                     IAAGGLEPFIARIEQVMGDDHTSLEVAAALLKIQSGAADAARQHKPGKK"
     gene            2326..3993
                     /locus_tag="PK679_07470"
     CDS             2326..3993
                     /locus_tag="PK679_07470"
                     /inference="COORDINATES: protein motif:HMM:NF014510.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55833.1"
                     /translation="MISVLLVHDNSDIIESTRAFLERHGDVRIDVVHSTKQALEKART
                     RKYDLIISYHRIPDIDGIEFLADMTGIEFHRELKSRLPSVPFILYVREGRDTLILGDI
                     NAAAEVPVPRRPSPPPVTEMRDMIYQSILRRKAERDQVLRADLLSAILSVTPLWLCQV
                     IGGKVEWVNSTMARALGMDAAALKGRDIAALFPGKEECDRAFREFALRVDDQGWGHAE
                     SAIKAKDGTLVPVYMKIRPMDPQDPSRGRILVIEDRTEKNRLLDAIREQEIRYREFLN
                     NASSLIVKLDPEGAVTFFNTHAQAFFGYSEAEIVGKRLQDTLIPAGSRKDAPDFTRDT
                     RLVHEGRGLSITEMVLRSGEPAWVAWTLSPIRDEQGKLVEVVCIGHDITDHTHRDRRR
                     ISTAAWRDTVIAGTDVQDEVFDSVLHICMEIAREGREGKQVGTAFIVGDADAVLERSR
                     QLILNPVEGHPPAERMVTNPDIKEMIKELAQLDGAFVVRGDGQIEAAARYITVDTSRA
                     GVPKGLGTRHSSIAAITLDTKAVGIVLSQSGGRISIFRNGRIVQEIS"
     gene            complement(4192..5214)
                     /locus_tag="PK679_07475"
     CDS             complement(4192..5214)
                     /locus_tag="PK679_07475"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HPC55834.1"
                     /translation="MEESNRGEGIFRSALDALPFPACIVGPDGAVLFSNRAMDRTFGQ
                     GKPAPVLPDDALAIAGKARETGKRVRATVTVTVSGDQAVQFPVEATPLPGAATGKPGP
                     VLLSACITGEEDLLRELLVRDTSRRKLRELLATIRHDILNQLTILIGFLQYSEDLCQD
                     PGIREFIGKEENAGKAIQSLIEFTRKFQDLAIQEPAWIDLSLLATPVEVQKLPRDVLV
                     RVDCGHFEVFSPPLLSFVFSVLVENALDHATGLSRITITAAPRGDDLVIAVEDDGPGI
                     PPGERKMLFERGHGRHGGYSLWLAREIVRICGGTLDECGGEGRGARFEIRIPKGMWRK
                     RDDGAS"
     gene            complement(5305..6108)
                     /gene="thiD"
                     /locus_tag="PK679_07480"
     CDS             complement(5305..6108)
                     /gene="thiD"
                     /locus_tag="PK679_07480"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR00097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HPC55835.1"
                     /translation="MGRPIRPCACTVAGSDPSGGAGLQADLGVFSALGVHGLSVVTAI
                     TAQNTKAVTGIHVVPSSMVSLELGTLCDEFEIRAVKTGMLGDSGTIRVLAREIPAGIP
                     LVVDPVMVSTSRHTLLPADALDALVSDLLPRATVVTPNASEAEVLSGVAPIRDRADAL
                     RAGKKILGAGPEYVLVKGGHLRGESATDILVGADGEWCISTPRYPYAIHGAGCCFSAA
                     LCAFLAQGYPVVDSFARAKEFMDFLAGNAVQAPSGMHILSPSDWLRRKE"
     gene            6310..7782
                     /locus_tag="PK679_07485"
     CDS             6310..7782
                     /locus_tag="PK679_07485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 family protein"
                     /protein_id="HPC55836.1"
                     /translation="MSPTPEQLTVARGSAPLGLLPGMANRHGLIAGATGTGKTVTLRV
                     LAEQFSKIGVPVFLADVKGDLSGMAKPGGDNPKITARATELGLSGYSPRGFPVVFWDV
                     FGQQGHPVRTTVSDMGPLLLSRILDLSDTQADVLAVIFRIADEQGLLLLDLKDLQAMV
                     RYGGENAKDLRTRYGNISPATIGAIQRNLLTLEEQGGGVFFGEPSLDIGTLLRTDAEG
                     HGIINILAADRLLQSPKLYSTFLLWLLSELYENLPEVGDPEKPRLVFFFDEAHLLFAD
                     APRALREKVVLVVRLIRSKGVGVYFITQNPLDLPDDVLGQLGNRVQHALRAFTQKDQK
                     AVRAAAETMRANPALDAKAVITELRTGEALVSFLDAKGIPGVTERALIYPPESRLAPL
                     SPDERNEIIRASPFYGRYEAVHDRISAYEILAERAKSSPPAEKKAESPPGRRERSSSS
                     APAGRGTDALAKMAGSAARAAGSQIGREIIRGILGSMKRK"
     gene            complement(7834..8001)
                     /locus_tag="PK679_07490"
     CDS             complement(7834..8001)
                     /locus_tag="PK679_07490"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55837.1"
                     /translation="MHPCRSGGNTGPGLFPAREIPALAGMTIRETGVSGQGARFGIAV
                     PEGRFRKGVPA"
     assembly_gap    8046..8145
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <8146..8964
                     /locus_tag="PK679_07495"
     CDS             <8146..8964
                     /locus_tag="PK679_07495"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55838.1"
                     /translation="VPAWVASGFALGKLGRFREEIKACDQALALDPQNVEAWINRGFA
                     LGKLLRFSEKLVCCERAIQLDPSNARAWNARGHTLGELGRFEDELTCTAIATSLRPRY
                     VGAWVNRGYAFLKLRRFGEALECFSRALSIYPGFSSAWILKGIASCELGRFRDAVSCF
                     ARAEESRPLSGARNLYWKGLALSRTGMRKDAIRILEGVVREDPRHVDAWIELSNCYFL
                     TGEIEESVRCFMVAYGLDKESIRDCLSRAVTLLKEGRKEEGLRSLSEALGILVR"
     gene            9302..9760
                     /locus_tag="PK679_07500"
     CDS             9302..9760
                     /locus_tag="PK679_07500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55839.1"
                     /translation="MTYRTHAAHTTCPGCQEEVYLDELVKGRCPLCGCTLEDLDELEN
                     DVEELVDRADFSWLIFNYFLFKTFTDMGASPLKVMQLVSLYEEAIAREGQSSMDTRFE
                     LDLPPGRFDSVIPHRCDKCGKIFLGGGRKIIAGDLSLPGYRIVHRCRSCR"
     gene            complement(9861..11297)
                     /gene="proS"
                     /locus_tag="PK679_07505"
     CDS             complement(9861..11297)
                     /gene="proS"
                     /locus_tag="PK679_07505"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HPC55840.1"
                     /translation="MAEAEEGSLPPKEDFSAWYNELLWRAELMDVRYPVKGLYVWYPF
                     GFALRRNVYSLMRNLLDRDHQEALFPLLIPETELAKEAEHIKGFEDEVYWVTHGGSSP
                     LDVRLALRPTSECAIYPMYALWIRSHADLPLKIYQIVNTFRYETKHTRPLIRLREITS
                     FKEAHTVHGSWEEASMQVEAAIALYREFYDALAVPVIVSRRPDWDKFPGADFTIAVDT
                     VMPDGRTLQIGTVHHLGDHFSRTFQIRFEDAAGQQQYAFQTCYGISERCIAALVSLHG
                     DDRGLVLPPVVAPVQVVIVPIVTGKRKEEVSAAAARVGGRLASAGFRVRVDTREMRPG
                     AKYYYWEMRGVPLRLEVGPRDLDSRQVMAVTRLGEKTAIPDESLEEGVRKVLDSFVSR
                     LRERAGAHVQSRIRVSGSLPEVTEAVASGVTLVSWCGDRGCADAIEEKTRASVLGTDV
                     RLESCKQLQGPCIVCGREGKAALVGRSY"
     gene            complement(11308..11868)
                     /locus_tag="PK679_07510"
     CDS             complement(11308..11868)
                     /locus_tag="PK679_07510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HPC55841.1"
                     /translation="MSDLARNVATAAVILAVSIGMGVLTTVEDPSTGEKVITVLRDTI
                     LGGSADISGPFLAANLFFNNLQACLMMFLGGASLGIVTVFIITVNGFVIGSVLELVRQ
                     QHSLAFVLAAIVPHGIFEIPAFLLSGALGFMLARALWNEWMSGSDAAAEAAALGKTFL
                     FRVVPLVAVAALVEAFITPQILHFLV"
     gene            complement(11861..12709)
                     /locus_tag="PK679_07515"
     CDS             complement(11861..12709)
                     /locus_tag="PK679_07515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF63 family protein"
                     /protein_id="HPC55842.1"
                     /translation="MIGDFIEKYYIDPIRYGQPYNVVDTTTYALVLILAIYIIYRWLS
                     RSRTIRIDGDFVLVTLPYVVMGGLLRVVEDTGIVPVGWNYLLITPLIYFVMFLYTAGA
                     LFVSATLQEHGIIRDYHRPFAGAGIAGAAVTGLVLVSFGIRNGIIALDVLFFILLLAA
                     ATTAAVWVVMRRLLSWEYVSDPLYITLLFGQLLDASATSYGIDLHPLHYVEVHVVGSH
                     LIEWTGTAFSMFALKLLVLFPGIYILQRFRSEGPQALWHLILLAMITVGLAPGVRDMV
                     RMVLYV"
     gene            12722..13804
                     /locus_tag="PK679_07520"
     CDS             12722..13804
                     /locus_tag="PK679_07520"
                     /EC_number="1.1.1.261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent glycerol-1-phosphate
                     dehydrogenase"
                     /protein_id="HPC55843.1"
                     /translation="MSADPIKLLKTKGFDKSRWMQLPRDVVIGHDVISQIPEVCADLC
                     LEDSAMVFFGGANTRECAGDRVVSLLGETYSVSTFTVREMSMETIAEAEEAARGAGFL
                     VGVGGGRVIDCAKIVSYNLDRPFLSVPTAASHDGIASARASVPLVDGNASLEAHPPMG
                     IVADTAIIAAAPHRLLAAGCADVISNSTAVLDWELAHRLRHEVISEYAIALSRMTAEL
                     LMKNARSIKPHSEESAWMVTKALVSSGVAMSIAGSSRPASGGEHKFGHALERLAPGKV
                     LHGEACGIGTIMVMYLHGGDWRAIKAALRAIGAPTTPRDLGIDDETAVEALLAARTIR
                     PERFTILDTGLSRESAVRLVKMLYEE"
     gene            13794..14255
                     /locus_tag="PK679_07525"
     CDS             13794..14255
                     /locus_tag="PK679_07525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0179 family protein"
                     /protein_id="HPC55844.1"
                     /translation="MKSEKAAEQKPRVTLIGSTIARVGLEFIYEGPLPECDGCSVKKA
                     CHNLQKGRKYRIVGVRKTRHACSVHHQDACAIEVVEAPVRALISADMAIRNTRIVFET
                     SCTRQNCENFSLCNPEGVIPGEKYVVAEVIGSAPGACERGWKLQLVELRAA"
     gene            complement(14269..15153)
                     /locus_tag="PK679_07530"
     CDS             complement(14269..15153)
                     /locus_tag="PK679_07530"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HPC55845.1"
                     /translation="MTFISDFSCAAGVLAGLAIGDALGAPFEGGPPPGVPVRSFFSGG
                     RNPRKAGEFTDDTLQALALAESLVACRGFSSEDFMARLVRDYALHSRFYGPTSAAVFS
                     LVRSGTGIHEAASRVHAARGWSRSNGSVMRGAPIGVFFSGPEVEAVSHACSALTHADP
                     VPGACSAFVNRMVSDMCRGISRDQAFARALRRCRNAGVARVLGCFGSHTPVAGLDALE
                     ATHAALTVFMRSDRFSDCVSLAVGLGGDTDTVAAIAGALAGALYGLDGIPPEWVAHLA
                     GRERVLSVAHALWSGRRG"
     gene            15207..15473
                     /locus_tag="PK679_07535"
     CDS             15207..15473
                     /locus_tag="PK679_07535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0058 family protein"
                     /protein_id="HPC55846.1"
                     /translation="MQKEELLHLHMLMIHIKKYYETITNQEIPTKRYNSLEISPVHIH
                     KNKKCHKDAILALGEEIVTHLRNSQMMRVGYSPEAASEQVAAEH"
     gene            15485..17059
                     /locus_tag="PK679_07540"
     CDS             15485..17059
                     /locus_tag="PK679_07540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine(34) 5-carboxymethylaminomethyl
                     modification radical SAM/GNAT enzyme Elp3"
                     /protein_id="HPC55847.1"
                     /translation="MQKPDISREILEALTSRATRPGDVTKIKVEVCRKHGAPAVPRNS
                     ALLAAATPEERAVLRRLLLVKPTRTLSGVAPVAVMTSPFPCPHGKCLPCPGGPDHPFQ
                     SPQSYTGEEPAALRARDHGYDPYAQVRARLEQFELLGHHVDKVELIVMGGTMTSRPAD
                     YQEWFVRECVRAMNEYRGTVRAARPDTARVFGENEFSPVRCVATTFETRPDWCKKEHI
                     DRMLGLGVTKVELGVQHLDDSILSFNRRGCTVADTVEATCLLRNAGIKVGYHVMPNLP
                     GSDIDHDRRMFRELFDNPAFRPDFLKIYPTLVTPGSAIEELWKQGQYAPYPEDTLIDL
                     VAYAKSLLPCYVRLQRIQRDIPARLIVAGSRHSNFRQLCQQRLAAMGKACQCIRCREA
                     GRSEGGGPEELSVFSYDACGGREYFISVVSGSALIGFARLRTGGERWRPETEGSALLR
                     ELHVYGSVVPLGSSPSAEQRQHRRFGKKLLSAAEETAAAEGYRGITIMSGIGVRPYYR
                     RHGYERRGPYMHKKLA"
     gene            17056..18213
                     /locus_tag="PK679_07545"
     CDS             17056..18213
                     /locus_tag="PK679_07545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase small subunit PriS"
                     /protein_id="HPC55848.1"
                     /translation="MKAATFEFLRQRFSSYYGNARLIPPPSVPQREWAFIFFEPDAAD
                     THMRRHLGFETRDEVFSYIRSMVPAHAYYSTAYYSRPGAPTMGEKGWLGADLIFDLDA
                     DHLMRGPYDRMLERVREETEKLLEMLTGELGFSQKDVEVVFSGGRGYHVHVRDPAVRD
                     FGSSERREIIDYVCGIGLDPGRVLSHRTHSPRGWHHRYIDALAEYLLWLESLEEKERV
                     ATLTALEGVGKTTAEEFIRRVPSILSLLESAPADLSLRDPVISRVIRGLSSDREGRFL
                     ALLRDRAALADEPVTTDTKRLIRMPSSLHGGSGFRVTPLAPGELPGFDPLVDAVVFSD
                     REVAVEVAFPLTMPILGSVYRLEKGYARVPEALAVFLCCRGAAEIAGGSRA"
     gene            18210..>18811
                     /locus_tag="PK679_07550"
     CDS             18210..>18811
                     /locus_tag="PK679_07550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55849.1"
                     /translation="MNLDELRIILLSERETGRLVHIPPDLFASAHRSLNDLYKELHAC
                     SDPFSDEAQVLIQRIHAMRETLSDLFHIRAEKILSLARTQEDGHYIDRDELKRLLPEE
                     REMYDLIVQALGQARCRLLAETAHQPAVSAPPGGNEPCAPAAGAENATGTPSFVVSRV
                     LQDVEPFMGVDGRIYDLRREDIVTLPARNADVLCERNIVL"
BASE COUNT         3655 a         6042 c         5730 g         3284 t
ORIGIN      
        1 cgtgatcgtc ttcgcactcg tcctgttcgc cggtatcgcc gggttctccc tgctcgaggg
       61 gttttcgccc ttcgactcgc tctacctcac catcgtgacg gttgcaaccg tcggctacgg
      121 cgacctgcac ccggtcacgc ccgcgggaaa ggctctcgcg gttgccgtca tcgtgggggg
      181 cgtgggctgt ttcgtggggc tggtcacgaa cgcagtcgag cacctggcat accgggcgga
      241 gcgggagcgg cgcaggagaa agaccggcat cctcgtcggg ctcttcttct cgcagctcgg
      301 aacgtccctc cttgcctcct tctcgtggct cgatcccgaa agaaaagacc ttgcccgggt
      361 cctctcggac cccggctcct tttccggtga ccggctccgc acgctcgctg cagatctcgg
      421 cgggcgccgg tatgcgctcg acagccggaa ctgtgacctt gtcgcgctcc gggaggcgct
      481 cgggagaaag gtggacgtcc tctccatgct cctccagaac ccggacctcg acgaacattc
      541 gcgtttctcc gacctccttc aggcactcct gcacctctgg caggaacttg tgcaccggga
      601 agacctctcc gaactgccgg acaccgatta cgaccacctc tcgggagaca tcagccgcgt
      661 ctacggtctc ctcgtcgtcg agtggatcgt gtacatgggc cacctccgcc tcacgtaccc
      721 gtacctgtat tcgcttgccc tccggaccaa ccccttcgac gaaacggcat cggtgatcgt
      781 cagggactaa aatgcacggt ctcctgaggg gtacccggtg ggaagtgaca tacgccatgc
      841 gagccaatgt atggacagga ataactccat gaagacaatc tcatttgccg acctcgacgt
      901 gcccgaaccc ctcctccggg cgatcaggga tctcgggttc gaggaaccga cacccatcca
      961 gtcccttgca atccccgtga tccgcgaagg ccacgacatg gtgggccagg cccataccgg
     1021 aacgggcaag acggcggcgt tcggaatacc gctcctcgaa atgctcgagc cggaccgccc
     1081 cgcggtgcag gccctcgttc tctgcccgac acgcgaactt gccatccagg tctccgagga
     1141 actccggaaa ctcgcccggt acatgggcgg ggtctccgtc ctccccgtct acggcggcca
     1201 gcccatcgaa cgccaggtcg cggtcctgcg caagggtgtc cacgtcgtca tagcgacgcc
     1261 gggaaggctc cttgaccacc tttcccggcg gacagtcgac ctctcgcagg tccgggtgac
     1321 cgtgcttgac gaggcagacg agatgctcga catgggattt gcggaggaca tcgcaaagat
     1381 attcacccgc ctgcctgaaa aaaggcagaa cgtgcttttc tccgcaacga tgtccaggga
     1441 gatccttgcc ctggcacaaa aattcctgaa agacccccgg atggtcaggg tcgtccacgg
     1501 gcagcttgcg gttcccgtca tcgagcagcg gtacttcgag gtccgggagt cagaaaaggt
     1561 cgaagtcctc tcccgcctgc tcgactacta caaccctgac cttgcgctcg tcttctgcaa
     1621 cacgaagcgc cgggtggacg aggtcgcatc ccagctccag gcccgcggct acctggcaga
     1681 gtccctccac ggcgacatgg accagaagga acgcgaacgc gtgatgtcgc gcttcaggtc
     1741 acgctcgacc gacatcctcg ttgcaaccga cgtcgccgcc cggggaatcg acgtcgagga
     1801 gatcgggatc gtcttcaact tcgacgtccc gcaggacccc gagtactaca tccaccggat
     1861 aggcaggacc ggccgggcag gcaaatccgg gaaggcattc acgttcgtct cgggcaaaga
     1921 gatgtggaaa ctccgggata tccagaagta tgcacggatc cgcatcgccc gacacgctgt
     1981 tccggcagac gccgacctcg aggagcggcg gttcgtccac atcggggaga aggtccgcga
     2041 cgtgatcgcc gcagggggtc tcgaaccgtt catcgcccgc atcgagcagg tgatgggaga
     2101 tgaccacacg tcgctcgaag tcgcggcggc cctcctcaag atccagtcag gggcagcgga
     2161 cgcagcccgg cagcacaaac cggggaaaaa gtgaggcccc gcacacaaac cacgcctttt
     2221 actcggtgcg atcgggattt cgcaccggca attattaaat tctcacggaa ccaaccagtt
     2281 cctgaatagt gtcggggccg ggatgccccc atttcccgcg agaccatgat atccgtcctc
     2341 ctcgtgcacg acaattcaga catcatcgag agcacgcggg ctttcctcga gcggcatggt
     2401 gacgtccgca tcgacgtcgt ccattccacg aagcaggcac tcgagaaggc acggacacgg
     2461 aagtacgacc tcatcatctc gtaccaccgg atccccgaca tcgacgggat cgagttcctt
     2521 gccgacatga cgggaatcga gttccacagg gagctcaaat cccgtctccc ttccgtcccc
     2581 ttcatcctct acgtcaggga aggtcgcgat acgctcatcc tcggcgacat caacgccgcg
     2641 gccgaggtcc cggtcccgcg acggccgtcc ccaccgccgg tcaccgagat gcgggacatg
     2701 atctaccagt ccatcctccg gcggaaagcc gagcgggacc aggtgctccg ggcagacctc
     2761 ctctctgcca tcctctcggt cacgccgctc tggctctgcc aggtcatcgg cgggaaggtg
     2821 gagtgggtca actcgacgat ggcccgggcg ctcggcatgg atgccgctgc cctcaagggc
     2881 cgggacatcg cggcgctctt tcccgggaag gaggagtgcg accgggcatt ccgcgagttc
     2941 gccctgcggg tcgacgacca gggatggggc catgccgagt ccgcgataaa ggcaaaagac
     3001 ggcactctcg tgcccgtgta catgaaaatc aggcccatgg acccgcagga cccctcgcgg
     3061 ggccggatcc ttgtcatcga ggaccggacc gagaagaacc ggctcctcga tgccatcagg
     3121 gaacaggaga tacggtacag ggagttcctg aacaacgcca gcagcctgat cgtcaagctg
     3181 gacccggagg gggcggtcac cttcttcaac acgcatgccc aggcattctt cggctactcc
     3241 gaggccgaga tcgtgggaaa gcggttgcag gacaccctca tccctgccgg gtcgcggaaa
     3301 gatgcccctg atttcacccg cgatacgcgc ctcgtccacg agggtcgggg cctctccatc
     3361 accgagatgg tgctgcgttc cggcgagccc gcctgggtgg catggaccct ctcccccatc
     3421 cgggacgagc aggggaaact cgtggaggtg gtctgcatcg gccacgacat caccgaccac
     3481 acgcaccgcg accgccggcg gatcagcacg gccgcgtggc gcgacacggt catcgccggg
     3541 acggacgtgc aggacgaggt ctttgactcg gtcctccaca tctgcatgga gatcgcgagg
     3601 gagggacgcg agggaaagca ggtgggaacg gcgttcattg tcggtgacgc ggacgccgtg
     3661 ctcgagaggt cacgccagct gatcctcaac ccggtcgagg gccacccgcc tgccgagcgg
     3721 atggtcacga accctgacat caaggagatg atcaaggaac tggcccagct cgacggggcg
     3781 ttcgttgtca ggggcgacgg gcagatagag gctgccgccc gctacatcac ggtcgacacg
     3841 agccgggcag gagttcccaa ggggctcggg acacgccatt cctccattgc cgcgatcacg
     3901 ctcgacacga aggctgtggg catcgtcctc tcgcagagcg gcggcaggat ctcgatcttc
     3961 cggaacgggc ggatcgtcca ggagatcagc tgactccctt ctcttttccc tgtgcggact
     4021 cgtctccccc ctttgccgtg ttccccggag cgttcccggc gaaacgagcg gtccgtgacc
     4081 tgcaagggaa gctgccctca caagggccga caggtatggg agagcagcag gagaagggga
     4141 atcagggttt aaaacagggg ataaacagat cccgctcttt ttcgttccgg atcaggatgc
     4201 cccgtcatcc ctcttccgcc acatgccctt cggaatgcgg atctcgaagc gggcaccacg
     4261 gccttccccc ccgcactcgt caagagtccc accgcagatc cgcacgatct cgcgcgcgag
     4321 ccagaggctg tatcccccgt gccgcccgtg ccccctctcg aaaagcatct tcctttctcc
     4381 cggcgggata ccggggccgt cgtcttccac ggcaatgacg aggtcgtctc ccctgggtgc
     4441 tgccgtaatc gtgatccggg aaagcccggt cgcgtggtcc agggcatttt ccaccagtac
     4501 agaaaagaca aaggaaagga gcgggggcga gaagacctcg aaatggccgc agtcgaccct
     4561 gaccaggacg tctctgggga gcttctgcac ctccacgggg gtggccagca atgaaaggtc
     4621 gatccatgcg ggttcctgga tcgcaaggtc ctggaacttc cgcgtgaatt cgatcaacga
     4681 ctggatggcc tttcccgcat tttcctcctt tccgatgaac tcgcgtatcc ccggatcctg
     4741 gcacaggtct tcggaatact ggaggaaacc gatgaggatt gtcagctggt tgaggatgtc
     4801 gtgcctgatc gtggcaagga gctcgcggag tttcctccgg gatgtgtccc ggacgaggag
     4861 ctcgcggagc aggtcctctt ccccggtgat gcatgcagac aggaggaccg gtcctggttt
     4921 tccggttgca gccccgggaa ggggtgttgc ctccaccggg aactggaccg cctgatcgcc
     4981 cgaaaccgtc acggtcaccg tggccctgac ccttttcccg gtttcccgtg cctttcctgc
     5041 aatcgcgagt gcatcgtccg gcaggacggg ggccggtttt ccctgtccga aggtcctgtc
     5101 catggccctg ttggaaaaaa ggaccgctcc gtcgggaccg acgatgcagg ccgggaacgg
     5161 gagtgcgtcg agggccgatc ggaagatccc ttctcccctg ttactttcct ccattgcttc
     5221 cagggaccct cccgtatccc ccgtcatcca tgggttcaca tatcgcacct gaccctcaag
     5281 aagataccgg aggtctcctc ccggtcattc ctttcggcgg agccagtccg acggggaaag
     5341 gatgtgcatg ccggagggtg cctgcaccgc atttcccgca aggaagtcca tgaattcctt
     5401 ggcccgtgca aaggagtcga cgaccgggta cccctgtgcc aggaatgcac agagcgctgc
     5461 cgagaagcag caccccgccc cgtggatggc ataggggtac cgcggggtgg agatgcacca
     5521 ttccccgtcc gcacccacga ggatatcggt tgcactctct ccccgcaggt gtcccccctt
     5581 gacaaggacg tactccggcc cggccccgag tatctttttt cctgcacgca gggcatcggc
     5641 cctgtcccgg atgggcgcaa cacccgagag cacctctgct tcactcgcgt tcggtgtcac
     5701 cacggttgcc cgcggcagga ggtcggagac gagagcatcc agcgcatcag ccggaaggag
     5761 cgtgtgcctg ctcgtcgaga ccatgaccgg gtcgacgacg agcggtatcc cggccggtat
     5821 ctcccgcgca aggacgcgga tggttccgct gtccccgagc atgccggttt tcaccgcgcg
     5881 gatctcgaac tcgtcgcaga gggtaccaag ctcgagcgag accatggagg aggggacgac
     5941 gtggataccg gtcacggcct tcgtgttctg ggcggtgatc gcggtcacga ccgagagacc
     6001 atggactccc agcgcggaaa agaccccgag gtccgcctgc aggcccgcac ctccgcttgg
     6061 atccgaaccg gcaaccgtgc aggcacaggg ccggattggt cttcccatgc gatgcaatgg
     6121 ggccccgttg ggcaatatac cttttcgtca tgcgttctgt ctcttcgccg tattccgaca
     6181 gcgtttttgc ctcccgccgc gcccgtgcag aaaaacagga catcaccacg gggaacggca
     6241 caaccgggac ggggacgggt tacggttaag gcgccctcct gccctatatg agatcaggaa
     6301 ggattcccga tgtcccccac ccctgaacaa ctcaccgtgg cccggggttc cgccccgctc
     6361 ggcctccttc ccgggatggc aaaccgccac ggtctcatcg ccggtgcgac cggcacggga
     6421 aagaccgtga cactccgcgt cctggccgaa cagttctcga agatcggtgt gccggtcttt
     6481 ctggcagacg tcaagggaga cctttccggg atggcaaaac cgggcgggga caatcccaaa
     6541 atcacggcac gtgcaaccga actcggcctg tccggctatt caccccgcgg ttttccggtc
     6601 gtattctggg acgtctttgg ccagcagggg cacccggtga ggaccaccgt ctcggacatg
     6661 ggtcccctcc tcctctcgcg aatcctcgac ctttcggaca cgcaggccga cgtccttgcc
     6721 gtcatattca ggatcgcgga tgagcagggg ctgctcctcc tcgatttgaa agatctccag
     6781 gcgatggtcc ggtacggggg ggagaatgca aaggacctcc ggacccggta cgggaacatc
     6841 tcgcctgcaa cgatcggcgc catccagcgg aacctcctta ccctcgagga acaggggggc
     6901 ggagtgttct tcggggagcc ctcgctcgat atcgggactc tgctccggac cgatgcggag
     6961 gggcacggta tcatcaacat cctcgccgca gacaggctcc tgcagtcacc caagctgtat
     7021 tccaccttcc tgctgtggct gctttccgaa ctctacgaga acctgcccga ggtcggagac
     7081 ccggaaaaac caaggctcgt gttcttcttc gacgaggccc acctcctctt tgccgacgca
     7141 cccagggcac tccgggaaaa ggtggtgctc gttgtccgcc tcatccggtc caagggtgtc
     7201 ggcgtctact tcatcaccca gaaccccctc gatctgcccg acgacgtcct tggtcagctg
     7261 ggcaaccggg tccagcacgc cctgcgggca ttcacgcaga aggaccagaa agccgtccgg
     7321 gcggcggccg aaacgatgcg tgcaaacccg gccctcgacg caaaggcagt cattaccgag
     7381 ctccggacgg gggaagcact ggtctcgttc ctcgatgcaa agggtattcc gggtgtcacc
     7441 gagagggcac tcatttaccc cccggagagc cgccttgcac cgctctcccc tgacgagagg
     7501 aacgagatca tccgcgcctc ccccttctac ggcaggtacg aggccgtcca cgacaggata
     7561 tcggcttacg agatcctcgc ggaacgggca aaaagttcgc ccccggctga aaagaaggca
     7621 gagagtccgc ccggacggag ggagaggagt tcctcctccg ccccggccgg acgggggacg
     7681 gatgccctcg ccaagatggc agggagcgcg gcacgggcag caggatcgca gatcgggagg
     7741 gagatcatcc ggggaatcct cgggtcgatg aaacggaaat gaggggtgat ccccggttgt
     7801 gggaacccgc catccttccg ggctgttttc ttcttacgca ggcacccctt tgcggaacct
     7861 tccttccggg acggctatcc cgaagcgtgc accctgcccg gacacgccgg tttcccggat
     7921 ggtcattccc gccagtgcgg ggatctcccg tgcggggaag agaccaggac ccgtgtttcc
     7981 accactcctg caggggtgca tttatcgaac gtgacgggaa aaagtgtgag aaagggacga
     8041 aaaaannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnngttcc cgcctgggtg
     8161 gcatccggtt ttgcactcgg caaactgggg aggttccgcg aagagatcaa ggcatgcgac
     8221 caggctctcg cactcgaccc gcagaatgtg gaggcatgga tcaaccgtgg ttttgccctc
     8281 ggaaagctcc tgcggttctc cgagaaactc gtctgctgcg agagggccat ccagctcgac
     8341 ccctccaacg cccgcgcgtg gaacgcgaga gggcacactc tgggtgaact cgggcggttc
     8401 gaggacgagc tgacctgcac ggccattgca acatcacttc gtccccgtta cgtgggtgca
     8461 tgggtgaacc gcgggtatgc attcctgaaa ctgcgccgct tcggggaggc actggaatgc
     8521 ttttcccggg cgctctccat ttatcccggt ttctcctcgg cctggatact caaagggatc
     8581 gcgtcctgcg agctgggccg gttccgggac gcggtctcct gttttgcacg tgcggaagag
     8641 tcccggccgc tctccggggc acggaacctc tactggaaag ggcttgcgct ttcccgcacc
     8701 ggcatgcgga aggacgccat ccgtatcctg gaaggcgtgg tccgcgagga cccccgccac
     8761 gtggatgcgt ggatcgagct gtccaactgc tacttcctca ccggcgagat cgaggagtcg
     8821 gtccgctgtt tcatggtcgc ctacggtctt gacaaggagt ccatcaggga ctgcctctcg
     8881 cgtgcggtca cccttttgaa agaggggaga aaggaggaag ggctccgatc gctctccgaa
     8941 gctttgggga tcctcgtccg gtagtcccgc ccggcggagg ctcaacgcgc aggatgcaaa
     9001 gaccccctgc ccggccggtg ccacatagtt tttatacctg cgcattctcc cttatttgtc
     9061 cattgcgaca ccggaaagac cccgagcgca tggtttatct catggaggta caaataggaa
     9121 aggaaattgc cctggaccgg gtcaccccgg gatcggttcc caggatcgcc ccccggaatc
     9181 ctctccaggc gtgcggtgat tagacacggt accgttatgc ggaccatctc actacagcac
     9241 ggcgatgcag taaagacatg ttcccaccca tcaccggggt agagacaata cccatccaac
     9301 catgacatac aggacccatg ctgcccatac gacctgtccg ggctgccagg aagaagtcta
     9361 ccttgacgag ctcgtgaaag gccgctgccc cctctgcggg tgcacccttg aagacctgga
     9421 cgaactggag aacgatgtcg aggaactcgt ggatcgggca gatttctcct ggctcatctt
     9481 caactacttc ctcttcaaga ccttcacgga catgggcgca agcccgctca aggtgatgca
     9541 gctcgtctcc ctctacgagg aggcgatcgc cagggaaggg cagtcatcca tggatacccg
     9601 tttcgaactc gacctgcccc ccgggcggtt cgattcggtc atcccgcacc ggtgtgataa
     9661 atgcgggaaa attttcctcg gcggcgggag gaagatcatt gccggtgacc tctccctccc
     9721 gggctaccgc atcgtccacc ggtgcaggtc ctgccggtaa tccccaaaaa gcctgcagaa
     9781 gtgtcaggag ttcccggaca cagcgataaa ccggcgggga attccccccg catctctcct
     9841 ctttttcccg gcactgtccc ctaataggac cgtcccacga gtgctgcttt cccctcgcgc
     9901 ccgcacacga tgcacgggcc ctgcagctgt ttgcagcttt cgagccggac gtcagttccg
     9961 agcacgctcg cacgtgtctt ctcctcgatt gcatccgcac acccccggtc cccgcaccag
    10021 gagacgagcg tgacgcccga tgcaacggcc tccgtgacct cgggaagcga tcctgacacc
    10081 cggatgcggc tttgcacgtg tgcaccggcc ctctcccgga gtcttgatac aaaggagtcg
    10141 agcactttcc tgaccccctc ttccagggat tcgtccggga tcgcggtctt ctccccgagg
    10201 cgcgtaaccg ccatgacctg gcgggaatcg aggtcacgcg gccccacctc gagccgcagc
    10261 gggacaccac gcatctccca gtagtaatac ttggcgccgg gccgcatctc gcgtgtatcg
    10321 accctgaccc ggaaccctgc ggacgcgagc ctcccgccga cccttgcggc agcagcactc
    10381 acctcctctt tccgtttccc ggtgacgatg ggcacgatga cgacctggac cggcgcgacc
    10441 acgggcggca ggacgagccc cctgtcatcc ccgtggagcg agacgagggc tgcgatgcac
    10501 cgctcggaga tcccgtagca cgtctggaac gcatactgtt gttgcccggc ggcgtcctcg
    10561 aaccggatct ggaacgtgcg ggagaagtgg tcgccgaggt ggtggaccgt cccgatctgg
    10621 agtgtcctcc cgtcgggcat caccgtatcg accgcgatcg tgaagtccgc ccccgggaac
    10681 ttgtcccagt cgggccggcg cgaaacgatg acggggacag caagggcatc gtagaactcc
    10741 cggtagagtg caatggcagc ctccacctgc atagaggcct cctcccagct cccgtgcacg
    10801 gtatgggcct ccttaaacga cgtgatctcg cggaggcgga tgaggggccg ggtgtgcttc
    10861 gtctcgtacc ggaacgtgtt cacgatctgg tagattttga ggggaaggtc ggcatgggat
    10921 cggatccaga gggcatacat ggggtatatt gcacactcgc tcgtgggccg gagggcgagc
    10981 cggacatcga gcggggagga gccgccatgg gtcacccagt acacctcatc ctcgaaaccc
    11041 ttgatatgct ctgcctcctt ggcaagttcc gtctcgggga tgaggagcgg gaacagtgcc
    11101 tcctggtggt cccggtcgag aaggttcctc atcagggaat agacgtttct cctcagggca
    11161 aacccgaacg ggtaccagac gtacagtccc ttgaccgggt aacggacgtc catcagttcc
    11221 gcgcgccaca gcagctcgtt gtaccacgcg gaaaagtctt ccttgggggg cagggagccc
    11281 tcttctgcct ctgccaaaaa atgcacctca aacgaggaaa tgtaggattt gtggcgtaat
    11341 aaatgcctct acgagtgctg cgacagcgac gagcggcacg acgcggaaaa ggaacgtttt
    11401 cccgagggct gctgcctctg cggctgcgtc gcttcctgac atccactcgt tccagagcgc
    11461 ccgggcgagc atgaacccga gtgcccctga caggaggaat gccgggatct cgaagatgcc
    11521 gtggggaacg atggcagcaa ggacgaacgc gaggctgtgc tgctggcgca cgagttcgag
    11581 cacggaaccg ataacgaacc cgttcacggt gatgatgaac accgtcacga tgccaaggga
    11641 tgccccgccg aggaacatca tgaggcacgc ctgcaggtta ttgaagaaga gatttgctgc
    11701 aaggaacgga cccgaaatat ctgcactgcc gcccaggatc gtgtcccgga gcaccgtgat
    11761 gactttctcc cctgtggacg ggtcttccac cgtcgttaag actcccatcc cgatggaaac
    11821 cgcgaggata acggctgccg tggccacgtt gcgggcaagg tcagacatag agcaccatcc
    11881 gtaccatgtc cctgactccc ggtgcaaggc caacggtgat catggcgagg aggatcaggt
    11941 gccagagtgc ctgcgggccc tccgaccgga acctctggag gatgtaaatc cccgggaaga
    12001 ggacgaggag cttgagggcg aacatcgaaa atgccgtgcc cgtccattct atcaggtggg
    12061 aacccacgac gtgcacttcc acgtagtgca gggggtggag gtcgatcccg tagctcgtgg
    12121 cgctcgcgtc gaggagctgc ccgaagagga gggtgatgta gagcgggtcg ctgacgtatt
    12181 cccacgagag gagcctgcgc atcacgaccc agactgcggc cgtggtggca gccgcgagca
    12241 ggaggatgaa aaagaggacg tcgagggcga tgatcccgtt cctgatgccg aacgagacga
    12301 gcacgagccc ggtgaccgcc gcacccgcaa tacccgcacc ggcaaagggc cggtgataat
    12361 cgcggattat cccgtgttcc tggagggtgg cggagacaaa gagtgccccc gcggtataga
    12421 ggaacatgac aaagtagatc agcggggtga tcaggaggta gttccatccg accgggacga
    12481 tcccggtgtc ctccaccacg cggaggagtc ctcccatgac cacgtagggg agagttacga
    12541 ggacaaagtc cccgtcgatg cggatcgtcc gcgaccgcga cagccagcga taaatgatat
    12601 atatggcaag gatcagaacc agagcgtagg tcgttgtatc caccacgttg taaggctgcc
    12661 cgtaacggat cggatcgatg taatatttct ctatgaaatc cccaatcact tccggataca
    12721 tatgagcgca gacccgataa aattactcaa aacaaagggc tttgacaaat cccggtggat
    12781 gcagctcccc cgcgacgttg tcatcggcca tgatgttatt tcccagatcc ccgaggtctg
    12841 cgccgacctc tgcctcgaag acagtgccat ggtttttttc ggtggtgcga acacgcggga
    12901 atgtgccggt gaccgcgtgg tctccctcct cggggagaca tacagtgtct ccacgttcac
    12961 cgtcagggag atgagcatgg agaccatcgc cgaggccgag gaggctgccc gcggtgccgg
    13021 tttcctcgtg ggcgtcgggg gcggccgggt catcgactgc gcaaagatcg tctcctacaa
    13081 cctcgaccgg cccttcctct ccgtcccgac tgcagcctcg cacgacggga tcgcgtcggc
    13141 gagggcgtct gtccccctcg tggacgggaa cgcatccctt gaggcacacc ccccgatggg
    13201 catcgttgcc gataccgcga tcattgccgc ggctccccac cggctgcttg ctgcaggctg
    13261 cgccgacgtc atttccaact ccacggcggt tctcgactgg gaactggcgc accggctccg
    13321 gcacgaggtg ataagcgagt atgcaatcgc cctctcgcgg atgaccgccg agctcctgat
    13381 gaagaacgca cgcagcatca agccgcacag cgaggagtct gcgtggatgg tcaccaaggc
    13441 cctggtctcg tcgggcgtcg cgatgagcat tgccgggtcg tcccggcctg catccggggg
    13501 tgaacacaag ttcgggcatg cgctcgagag gctcgcgccg ggaaaggtcc tgcacggcga
    13561 ggcgtgcggg atagggacga tcatggtgat gtacctgcac ggcggtgact ggcgggcgat
    13621 taaggcggca ctgcgggcca tcggggcccc gaccaccccc cgcgatctcg ggatcgatga
    13681 cgaaacagca gtggaagctc tccttgccgc acggaccatc cggccggaaa ggttcaccat
    13741 cctcgatacg ggactgtcac gggaatcggc agtcaggctt gtgaagatgc tctatgaaga
    13801 gtgaaaaggc tgcagagcag aaaccgaggg tcaccctcat cgggagcacg atcgcccggg
    13861 tgggccttga gttcatctac gaggggccgc tccccgagtg cgacgggtgt tccgtgaaga
    13921 aagcgtgcca caacctccag aaggggagaa agtaccgcat cgtgggtgtc cgcaagaccc
    13981 gccacgcctg cagcgtgcac caccaggacg cctgtgccat cgaggtcgtg gaggctcccg
    14041 tccgcgccct catcagcgcc gacatggcca tcaggaacac ccggatagtc ttcgagacct
    14101 cctgcacgcg gcagaactgt gagaacttct ccctctgtaa cccggaaggg gttatccccg
    14161 gcgagaagta cgtggtcgca gaagtcatcg ggagtgcgcc gggtgcctgc gagaggggat
    14221 ggaaactcca gctcgttgag ctccgggcag cctgaaaacc ccgcctgctc atccccgtcg
    14281 tccggaccag agggcatggg caacggaaag caccctctcc cggcctgcga ggtgtgccac
    14341 ccattcaggg ggtatcccgt cgagaccgta cagggctccc gcaagggcac ccgcgattgc
    14401 agccaccgtg tcggtatcgc cgccaaggcc gacagcaagg gagacgcagt cggaaaacct
    14461 gtccgagcgc atgaagaccg tgagggcggc gtgcgtcgcc tcgagtgcat cgagaccggc
    14521 aacgggggtg tgggacccga agcagccgag aacgcgggca acaccggcat tgcggcacct
    14581 ccggagagcc cgggcgaatg cctggtcccg ggagattccc cggcacatgt cgcttaccat
    14641 gcggttcacg aacgccgagc aggcgcccgg caccgggtcc gcgtgggtca gggcagaaca
    14701 tgcatgcgag actgcctcca cctcagggcc ggaaaaaaag acgccgatcg gcgcaccccg
    14761 catcacgctc ccgttgctcc tgctccatcc ccgggcggca tggacgcggg acgccgcctc
    14821 gtggatgccg gtcccgctcc ggacgaggga aaagacagcg gcggaggtcg ggccgtagaa
    14881 cctgctgtgg agcgcatagt ccctcacgag ccgggccatg aagtcctcgg aggaaaaacc
    14941 gcggcatgca acgagggact ctgccagggc aagtgcctgg agcgtgtcat ccgtgaattc
    15001 cccggctttc cgcgggtttc tgccgccgga aaaaaacgag cggacgggca cacccggagg
    15061 gggtcctccc tcgaagggcg cacccaacgc gtcaccaatt gcaagccccg caaggacgcc
    15121 tgcagcgcac gaaaagtccg atataaaggt caccaataaa gtatatctgg tcaggaaaaa
    15181 agtagtcatt tgaagaaggt gatagtgtgc aaaaggaaga gctcctccat ctccacatgc
    15241 tgatgatcca catcaagaaa tactacgaaa ccatcaccaa tcaggaaatt ccgacaaaac
    15301 ggtacaattc cctcgagatc tctcctgtcc acatccacaa gaacaagaag tgccacaagg
    15361 atgctatttt ggccctcggc gaagagatcg tcactcacct gcgcaacagc cagatgatga
    15421 gggtcgggta ttcccccgag gcggcttccg agcaggtcgc tgctgaacat tgaatttttc
    15481 ctccatgcaa aagcccgata tctcccgcga gatactcgag gccctcacct cccgtgcgac
    15541 ccggcccgga gacgttacga agatcaaggt cgaggtctgc aggaaacacg gcgctccggc
    15601 ggtcccccgg aactccgctc tccttgctgc ggcaacaccg gaagaacggg ccgtcctccg
    15661 gaggctcctc ctcgtcaaac cgacgcggac gctctcgggt gttgcacccg ttgccgtgat
    15721 gacgtctcct ttcccctgcc cccacggcaa atgcctcccc tgccccggag ggccggacca
    15781 tcccttccag tccccccaga gctacacggg agaggaacct gcggcattgc gggcacgcga
    15841 tcacggatac gacccgtatg cgcaggtcag ggcacgcctc gagcagttcg agctcctcgg
    15901 acaccacgtc gacaaggtgg aactgatcgt gatggggggg acgatgacgt cccggccggc
    15961 ggattaccag gaatggttcg tcagggaatg cgtccgtgcc atgaacgagt acagggggac
    16021 cgtgcgggcc gcccggccgg acacggcacg cgtctttggg gagaacgagt tctcgcccgt
    16081 ccggtgcgtt gccaccacct tcgagacacg tcccgactgg tgcaaaaagg agcatatcga
    16141 ccggatgctc ggactcgggg tgaccaaggt tgaactgggg gtccagcatc tcgacgattc
    16201 catcctctcc ttcaacaggc ggggctgcac ggtcgccgac acggtggagg cgacgtgcct
    16261 gctgcggaat gcggggatca aggtcgggta ccacgtcatg cccaacctcc cggggagcga
    16321 tatcgatcat gaccgccgga tgttccgcga gctcttcgac aaccctgcct tccggcccga
    16381 ttttctcaag atatacccga cactcgtgac gcccggctcc gcgatcgagg aactctggaa
    16441 gcaggggcag tacgccccat accccgagga cacactcatc gacctcgttg cctacgcaaa
    16501 gtcgctcctg ccctgctacg tcaggctcca gcgcatccag cgggacatcc cggcacgcct
    16561 gatcgtggca ggatcgcggc acagcaactt ccgccagctc tgccagcagc gccttgccgc
    16621 gatgggaaag gcgtgccagt gcatccggtg ccgcgaggca ggcaggtcgg agggaggcgg
    16681 cccggaagaa ctctcggtct tctcctacga tgcatgcggg gggcgcgaat acttcatctc
    16741 ggtcgtctcg ggcagtgccc tgataggatt tgcccggctc cgcaccggcg gagagaggtg
    16801 gcggcccgaa acggaaggct cggccctcct ccgcgaactc cacgtgtacg gaagcgttgt
    16861 gccgctcggg agttccccct cggcagaaca gaggcagcac cgcaggttcg ggaagaaact
    16921 cctctctgcc gcggaggaga cggcggcagc cgaagggtac cgcgggatta ccatcatgag
    16981 cgggatcggg gtccggcctt actaccggcg tcacggatat gaacggcggg gaccatacat
    17041 gcacaagaag ctcgcatgaa ggctgccacg ttcgagttcc tgcgccagcg tttctcctcg
    17101 tactacggga acgcccgcct catcccgccg ccctcggtac cccagcggga atgggccttc
    17161 atcttcttcg aaccggatgc tgccgacacc cacatgcgca ggcacctggg gttcgagaca
    17221 cgcgacgagg tcttctccta catccggagc atggtcccgg cccatgccta ctactcgacg
    17281 gcctactaca gcaggcccgg tgcaccgacc atgggcgaga aagggtggct cggtgccgac
    17341 ctcatcttcg acctcgacgc agaccacctc atgcggggac catacgaccg gatgctcgaa
    17401 cgcgtccggg aagagacgga aaaactcctc gaaatgctca ccggggaact cggtttttcc
    17461 caaaaagacg tggaagtagt cttttcgggc ggcaggggct atcacgtgca cgtcagggat
    17521 ccggccgtcc gggacttcgg cagcagcgag aggcgcgaga tcatcgatta cgtctgcggt
    17581 atcggccttg acccgggacg cgtcctctcg cacaggacac attcaccccg cggatggcac
    17641 catcgctata tagatgcact cgccgagtac ctgctatggc tggagagcct ggaggaaaag
    17701 gaaagggttg ccaccctgac ggcactcgag ggggtgggaa agacgaccgc tgaagagttc
    17761 atccggcggg taccgtccat cctctcgctc ctcgagagtg cccccgccga tctctccctg
    17821 cgtgacccgg tcatctcccg ggtcatccgt ggcctgtcat ctgacaggga ggggcgcttt
    17881 ctggcactcc tccgcgaccg ggcagccctt gccgacgagc ccgtgacgac cgacacgaag
    17941 aggctgattc gcatgccctc gtccctccac ggcgggagcg gtttccgggt caccccgctt
    18001 gcccccggcg aactgcccgg ttttgacccc ctcgtggatg ccgtggtctt ttcggaccgc
    18061 gaggtcgctg tcgaggtcgc gttccccctc acgatgccga tcctcgggtc cgtgtacagg
    18121 ctggagaaag ggtatgcacg cgtccccgag gccctcgctg tcttcctctg ctgccggggc
    18181 gcagccgaga ttgcaggggg gagcagggca tgaacctcga cgagctgcgg atcatcctcc
    18241 tctccgagag ggagaccggg cggctggtcc atatcccccc tgacctcttt gcatcggcac
    18301 acaggagcct caacgacctc tataaggaac tccatgcatg cagtgacccc ttctcggacg
    18361 aggcacaggt cctcatccag cgtatccacg cgatgcgcga gacgctttct gacctcttcc
    18421 atatccgggc ggaaaagata ctctcgcttg cacgtaccca ggaagacggg cactatatcg
    18481 accgcgacga gttaaagagg ctgcttcccg aagagcggga aatgtacgac cttatcgtgc
    18541 aggcactcgg gcaggcccgg tgccggctcc tggcggagac tgcccaccag cccgcggtgt
    18601 ccgcacctcc cggcggaaac gaaccatgcg ccccggcagc cggtgcggaa aatgcaacgg
    18661 ggacaccttc ctttgtcgtc tcccgggtcc tgcaggacgt cgagccgttc atgggcgtgg
    18721 acggcaggat ttatgacctc cgccgcgagg atatcgtgac cctgcccgcg aggaacgcgg
    18781 acgtcctgtg tgagcgcaac atagtcttaa a
//
LOCUS       DAOOJU010000031        17021 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_3267_length_17021_cov_15.613698, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000031 DAOOJU010000000
VERSION     DAOOJU010000031.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 17021)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 17021)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17021
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3267_length_17021_cov_15.613698"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..604
                     /locus_tag="PK679_07555"
     CDS             <1..604
                     /locus_tag="PK679_07555"
                     /inference="COORDINATES: protein motif:HMM:NF019314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HPC55850.1"
                     /translation="FAATEIFIFVFMEIVTKVESVRMVIFRTARLQDYIVFVGIFGAF
                     SIFGTYIGIQGVFGAITNIRDIAPIVAGLVAGPYAGLAVGLIGGLHRMTLGGASCIAC
                     SVATVLSGLIAGLVFRFNRGKIMGIVPAIGFGVLMEGLHGLLVLVLVRPFSEAMEIVM
                     TSIPQMMVAVSLGVGIAIIIVHNIIREDEMVSAHSGEKSL"
     gene            complement(938..1078)
                     /locus_tag="PK679_07560"
     CDS             complement(938..1078)
                     /locus_tag="PK679_07560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55851.1"
                     /translation="MADDTWTEIAFRLEDPDEQQDPWQATRDPWVADVYQNLLSRRQE
                     RA"
     gene            complement(1071..1622)
                     /locus_tag="PK679_07565"
     CDS             complement(1071..1622)
                     /locus_tag="PK679_07565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55852.1"
                     /translation="MTAGRESVFSGGDQGKDMGRVAGLRSLAVSFRYIDTLLGTVEDA
                     LGNPSPRNRAFCHCIPDIPAAERERLEEGIRALRERLKGEMDRLGISSHAGAVPASRA
                     VRADLATIAITLEELTRKDWTDLGWTQEGAGDLRSVFAGLQEMVGDLLDTAGSSGCRS
                     PPGNEWDKRGGRHTLHERGEENG"
     gene            complement(1660..2946)
                     /gene="eno"
                     /locus_tag="PK679_07570"
     CDS             complement(1660..2946)
                     /gene="eno"
                     /locus_tag="PK679_07570"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HPC55853.1"
                     /translation="MDKTAIRKVHAREILDSRGNPTVEADVVLACGVTGRAASPSGAS
                     TGTHEAVELRDGAMDRYRGKGVKKAVEGVNGKIAAALAGMDATDQEAVDRKMIALDGT
                     ENKATLGANAVLAVSMAVARAAAAAQGLSLWKYLERPGRVTMPVPMMNIMNGGVHANW
                     QGSDFQEYMIVPFGAPSFPEALRFGSETYHALKEILKKKGYSTGVGDEGGFAPSVRSN
                     EEPLVLMTEAIEAAGYTPGREIGFALDPASSGFFEGGEYILRTEGRRLSSAGMIDYYE
                     SLVSRYPIVVIEDGLAEDDWSGWKELTRRLGDRVELVGDDLFVTNVSRIRKGIREGVA
                     NAVLIKPNQIGTVTETIAAVELAHSSGWGAMVSHRSGETVDTFISDFTVAMGTGHLKT
                     GAPARGERVEKYNQLLRIEEEMGGKARYAGRKAFVR"
     gene            complement(2959..3858)
                     /locus_tag="PK679_07575"
     CDS             complement(2959..3858)
                     /locus_tag="PK679_07575"
                     /inference="COORDINATES: protein motif:HMM:NF012647.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="HPC55854.1"
                     /translation="MTWQGAGPVPARFPDLPSGTVEYVRSRRCPSGGYCFYRLDEPNA
                     GDTCFALGILSFLGEMDADEKTIRFLQNLQYPDGSYPSLSCALFAGWALRMLHAEPFH
                     DPSGYILRSLPRPDPRTRVIESLSLFEPLRAWAALADLYGVKIPPDSGEAVTATVLSF
                     RSETGGFGVPVPTLQDTRIALEILAFLGQGCNDGGTVSFMNACGDPEFGFLGRPGSKP
                     AFLEQVHAGLRLALLLGVAPRHIDACREFVRECGHPSGGFVRSVFGGSPTLEYTARAV
                     ESLAILAGFSRGRRNYSFPAPYM"
     gene            complement(3861..5687)
                     /locus_tag="PK679_07580"
     CDS             complement(3861..5687)
                     /locus_tag="PK679_07580"
                     /inference="COORDINATES: protein motif:HMM:NF012570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HPC55855.1"
                     /translation="MQDPAQDITSVSPRNGDPAFPPAATPDLSSLLGRAISILHDLGP
                     AMEPQERALSGLRDRLSEGRFQLAVLGQFKRGKSTLLNALLGEDILPSSVIPLTAIPT
                     FIRHGTERTVKVHFLEQGKDGTIPCQSPEEMNRILLDYVSEEANPKNRKGVSSVEITH
                     PSRILRDVVLIDTPGIGSTHRHNTEMTLNFLPQCDAALFLVSADPPITEVEVDFLRHV
                     REKVACIFFVQNKVDYLTMPERETVIAFIRKVLSEKAGIAPEEKIFPVSAKQALLARL
                     TGDETLLASSGISAITEHLVDFLAREKTRVLSEAVRRKALDVLHDASLRVSLERKSLG
                     MPIADLEKKLSLFQNKVDEAERQRRQTQDVLSGDHRRVVALLEEVCAGIREQAEMHLQ
                     GVASRAMSTGGDPDPRNVEAAIAQEIPVYFEHTLGEVTERFDREMVAVLSAHREKAEA
                     LSESIRAAASTIFEIPHHRASPGGPLVLAREPYWVSRRTWSGMLGLISPDLVDRALPR
                     AMREKRLRGRIAREIHSLVVQNVENLRWATLQNVDAAFRIFSREIDEELARTIDATHG
                     AIAAAYRQRKERAEEIAERVRFLGEASRTLQELIAALSDTPG"
     regulatory      complement(5732..5794)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            6246..8906
                     /locus_tag="PK679_07585"
     CDS             6246..8906
                     /locus_tag="PK679_07585"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC55856.1"
                     /translation="MVDPEKESGRRPGPSYSFSHQLLFWMVILILVLAIGITYFDYRQ
                     AEETYQKNARAMEELTEANIAGTIIVIDSAYEMYDSSLNNEMKNAFSLFQKEYERSGN
                     DPAKMDLDALKEALGNEMDLYIINESIMVEYTTDPSDLGLDFSQWPYAYNYLKDLLQR
                     DGFFPDRIVHHATSGKLVKYAYMPTPDHRYILELGLSGKALEERPHIRYQDSLRAIAL
                     NNPNVVSYRAYDTLGRVIGNNTSSAQSTPPFIRQVISERKPLEIVDPNNNTLTRYLFV
                     DLTNHSYVSDVSWIIELVYDQSELKDQLTTLLLNHALVALLAVTFSIVLAIVLSRRLT
                     RPIAQMVHDIDTISRGDLEYPLAPPRTTEFERITRSVTSLVASLRGMIRQLQQTELEL
                     VRKGENYRAVVENQTELIARFLPDGTHVFVNEAYCRYFGLPWPDILGHKAWPKVPPED
                     DELIRRHFSSLSPENPTATIEHRVITPDGQERWVQWNDRAIFDSDGNIIEYQSVGRDI
                     TEKKHMEEDLTRSEQKFRDLAGLLPQVIFETGPKGEILYVNKSAYTIFGYTPEEVRSG
                     VDIFDVIHPDDRDLAAGNFARSLQGEKIDGAEYRMVRKDGSSMMGMVYSSPIESDGRI
                     TGIRGILIDITHIKDVERDLRNLNEELERRVRERTQDLESAVRELEAFSYSVSHDLRA
                     PLRAIDGFSSIILTHYDEALHPEIRELLRKIRTNAQKMGDLIDSILNFSRMSRQPLSR
                     QTVYPARIVAEQLAQLRGMQDGRDVTVRTGDLPPCEGDPVLLTQVFQNLLSNAFKFTR
                     TRKHAEIEVGSEKQDGKTVYYVRDNGIGFDMKYASKLFTVFQRLVDEKEYEGTGIGLA
                     IVQRIIQRHGGRVWATGRVGKGATFYFTLE"
     regulatory      8970..9033
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            9178..9864
                     /locus_tag="PK679_07590"
     CDS             9178..9864
                     /locus_tag="PK679_07590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HPC55857.1"
                     /translation="MVRTDTSIRLMGLLLDGKPVTDKQLADAIGFKNPRNIARHLESF
                     ASSGYIRILPQTGRDNYRLFQLTDKKDGLLKLYQSRFYRVLRPRIREIDWFIDQVAAG
                     FSPLPRDLFNLIREMMKKSHTFFSLIAGHSSHDQLLSSYSLYLFPCRLMNRDDPLFQA
                     CYLYAQLYAESITRDIREGGLSEGFLEPLDAIQKVILQLGPPAITDSSRDHPGYKGLH
                     CTGQNPLQSS"
     gene            complement(10366..11571)
                     /locus_tag="PK679_07595"
     CDS             complement(10366..11571)
                     /locus_tag="PK679_07595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HPC55858.1"
                     /translation="MGIQSVTSRAIAFRLILVLGVVSLLGDIVYEGGRSVTGPYLLLL
                     GASALTVAIVSGLGEFLGYGIRLLSGYISDRTGMYWALTIVGYLMVGAVPLLVLAGSW
                     EVAAIFILVERVGKGLRSPARDAILSHASKQVGRGWGFGIHEALDQVGAVIGPVLFAV
                     SIAFSGRYETGFALLAIPFVLLVAALLYARFSVPDPVKFEDDSRAISGDGTLQVSRVM
                     RPYGAFTVLTMAGFAVFPLMAYHFSAASVVPEAQVPVFYAIAMATDALFALAMGRVYD
                     RVGLSVLVAVPVINIPIAALAFMGGYTGALAASILWGLSMGGQETVLRAALADLTSVG
                     KRGTVYGVFNTLYGGAWFAGSVVMGALYGLNLALLVLYCIVMQAGALAAFVWLRRTVE
                     TGRIERAGG"
     gene            12038..12856
                     /locus_tag="PK679_07600"
     CDS             12038..12856
                     /locus_tag="PK679_07600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HPC55859.1"
                     /translation="MATIHVNPDSCTRCGICAIVCPMGIVSAPGEQTLPGVPDAASAL
                     CIRCGHCEAYCPAQALLLCDRADEKVWIPQGAGSVNPQDLGIYMRKRRSVRNYRDDPV
                     PAEKVREVLDIARYAATGGCGQPVEWTVVLDRARVRRIAELTIEWLKTLRDSDHPMRG
                     VIPVLVGAWESGRDVICRDAPHLLFAHIPEENPVAFIDAVIALTYFDIAAPAHGLGTC
                     WAGFVAMAAAAHAPLRKEINLPAGRKVAYAMMFGYPRYAVYGIPPRKPLAVTWL"
     gene            12925..13368
                     /locus_tag="PK679_07605"
     CDS             12925..13368
                     /locus_tag="PK679_07605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HPC55860.1"
                     /translation="MKSIKKPDEAEEVFRSGITRSSAVFSTFAEENGLPADVARKIAC
                     GFGAGVSKTGNMCGAVSGAILAIGLKYGKSERTDTAANEKTRALVREFIAEFIRRNGS
                     ITCTELLGYNLANPDEYQKAAESGLFLSRCPRYVRDAADILERIL"
     gene            13696..14541
                     /locus_tag="PK679_07610"
     CDS             13696..14541
                     /locus_tag="PK679_07610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55861.1"
                     /translation="MKTLSCLGLAITLLLVLAAGCTHSENYTVTETPAPITGNAEMTG
                     ALAAVTAEIQESLNDIDNQVSGAATALGKTGISGPAAEAILERAALSHPAIQDIITYD
                     TGGIVRAAEPGGARDLVGRNLTGQEIVRKALQEQRPLMSDLFSLTEGGAGAVIAYPVH
                     AQDGTFIGVVSLAFSPPALVTPIAGDATSGTPFSVMVTETGGRILYDADPAQVGKETF
                     NETMFAGFPEILDIARNLPGNRTGHATYSFSGSGSKNVIRKEAFWSTVSLHGTEWRVF
                     VIREI"
     gene            complement(14836..15042)
                     /locus_tag="PK679_07615"
     CDS             complement(14836..15042)
                     /locus_tag="PK679_07615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histone family protein"
                     /protein_id="HPC55862.1"
                     /translation="MADLPLAAVVRIAKKSGAERVGSDAAAALVAQSEEYIAELVKKA
                     NKFAMHAGRKTIKEEDVELAAKEV"
     gene            15341..16966
                     /locus_tag="PK679_07620"
     CDS             15341..16966
                     /locus_tag="PK679_07620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HPC55863.1"
                     /translation="MKRIVLLTVFIGILAVIAVFSAGCLSEKNPAGTTGGRPQYTIGV
                     DTDYRPFAYMDEEGNMTGFDIDAARWIAARKGFDPVFVGFAWDDIIPALEQGKIDMIY
                     SGLTVTPEREERVDFTRPYYTTNQSVAARTGSNVSMQDFHAGRLRVGAQAGSTGAAWV
                     AENLAGAGLMPAEKLVLYPDVSSMAAGLEGGAVQAIIGDAPPLILMAKEKPFSIIGEI
                     PTRERYAIAVRKGDTPTREMMDDGLSQLMKDPSWSLLLEKYGLGGAGSGGVPGRGQPE
                     TTEELKDYVDEAASFALSHGRDAAIAAFQDVNGPFVSGDTYVYALDYSGVALALPFQP
                     GMVGTNFLPLRDATGKPYTDIEIRLARAGGGFILYHYPKPSENGTSRLKISYVRPVDD
                     TYWIGAGIYTDEDALIDPELREFVANAREFALSHARDDALAALNDPAGPFINGDLYVF
                     AYDYNGTVLAWPYRPDQVGKNRYNETDMMGSYHVREMIAKARQGGGMVDYYSTNPFTN
                     RTALKVSIVMDVDGSWFIGAGRYIEPGPFRLVS"
BASE COUNT         3616 a         5074 c         4797 g         3534 t
ORIGIN      
        1 ctttgcagcg acggagatct tcatcttcgt tttcatggag atcgtcacga aagtcgagtc
       61 cgtccgcatg gttattttca ggactgcaag gttgcaggac tacattgtct ttgtgggtat
      121 tttcggggca ttttccatat tcgggacgta catcgggata cagggagtgt tcggggcgat
      181 cacgaacatc cgtgacattg cccccatcgt cgcggggctt gtcgccggtc cctatgccgg
      241 gcttgcggtc ggcttgatcg gcggcctcca ccgtatgaca ctcgggggcg cctcctgcat
      301 cgcctgttcg gttgccaccg tcctttccgg gctgattgcc gggcttgttt tccggttcaa
      361 caggggaaag atcatgggta tcgtgcccgc aatcgggttc ggcgtcctca tggaaggact
      421 ccatggtttg cttgtccttg tactcgtccg gcctttttcc gaggcgatgg aaatcgtcat
      481 gacttcgatc ccccagatga tggtcgcggt ctccctcggc gtcgggatcg cgatcattat
      541 cgtccacaac atcatcaggg aagatgagat ggtatctgcc cattcgggag aaaaatcctt
      601 atgaaccctc tcgtgacaca ggaggaaacg ggactcccga ggagtcgata atgtgataag
      661 aaacgaatgt gtgggctgaa tcgacccgcc actcccggaa aaggatgaat ccgctgcccc
      721 tcccaagttc atgccccgga ggcagttttt cacagctgtt ttttgtagca ggactcctgt
      781 tctttccccg ataaactctc acggaactgg cggagagact aaaaaatctg caaatcccgt
      841 tttccaccgg gacttttgaa gagattcctt atccggatga ggttgagagg acaggacagc
      901 ccggcacctg agaacgggtc aggggtacag tcccccgtca ggccctctcc tgccggcggg
      961 aaagaaggtt ctggtaaacg tcagcgaccc acggatcacg cgttgcctgc cagggatcct
     1021 gctgctcgtc cgggtcttca agtcggaatg ctatctccgt ccacgtatcg tcagccattc
     1081 tcctcccctc gttcatgaag tgtatgtctt cccccacgct tatcccattc gtttcccggt
     1141 gggctcctgc atccggacga tccggcagtg tcaaggagat ccccgaccat ctcctgcagc
     1201 ccggcaaaaa cggaacggag gtctcctgct ccttcctgcg tccacccaag gtccgtccag
     1261 tcctttcgcg tcagttcctc gagggtgatg gcgatcgttg cgaggtcggc acggacggcc
     1321 cgcgatgcgg gaacggcacc cgcgtgggaa gagatgccaa gcctgtccat ttcccccttg
     1381 agccgttccc ggagagcccg gatgccttct tccagccgct cgcgctccgc agccggaata
     1441 tcggggatgc aatgacaaaa tgccctgtta cggggagagg gattcccgag cgcgtcctcg
     1501 acggtgccga gcagggtatc gatgtaccgg aacgagaccg cgagagatcg caggccggcc
     1561 accctgccca tatcctttcc ctggtcgcca ccggaaaaca cggactctct ccctgctgtc
     1621 acacacactc acccgtacgc tgcatgtgcc ggatcagcat caccggacaa acgcctttcg
     1681 tcccgcgtag cgtgctttcc cacccatctc ctcctcgatg cgcaggagct ggttgtactt
     1741 ctcgacccgc tcgccccgtg ccggcgcacc cgtcttgagg tgccccgtac ccatcgcgac
     1801 cgtgaaatct gaaataaacg tgtcgaccgt ctcaccgctc cggtgggaga ccatggcacc
     1861 ccagccactg gaatgagcaa gttccacagc agcaatcgtc tctgtcaccg tcccgatctg
     1921 gttgggcttg atgaggacgg cgtttgccac cccttcgcgt atgcccttcc ggatgcggga
     1981 gacgttcgtc acgaagaggt cgtcgccgac gagctcgacc ctgtcaccga ggcggcgtgt
     2041 cagctccttc cacccggacc agtcgtcttc tgcgagaccg tcctcgatca cgacgatggg
     2101 gtaacgcgag acgagcgact cgtagtagtc gatcatcccg gcagacgaaa ggcggcgtcc
     2161 ctccgtccgg aggatgtatt ctcccccctc gaagaacccg ctcgatgcag ggtccagtgc
     2221 aaaccctatc tcgcgtcccg gcgtataccc tgcggcctcg atcgcctcgg tcatgaggac
     2281 aagcggttcc tcgttggatc tgacagacgg ggcaaaaccc ccctcgtcac cgaccccggt
     2341 actgtaaccc ttcttcttca ggatctcctt gagggcgtgg taggtctcgc tcccgaaacg
     2401 gagggcctcc gggaagctcg gtgctccgaa aggcacgatc atgtattcct ggaagtcaga
     2461 cccctgccag ttggcatgga ccccgccgtt catgatgttc atcatcggga cgggcatcgt
     2521 gacacgtccg ggccgctcca ggtacttcca gagacttaaa ccctgtgccg ctgccgccgc
     2581 acgtgcgact gccatcgaga cggcgaggac ggcgtttgct ccaagggtcg ccttgttctc
     2641 cgtcccgtca agcgcgatca ttttccggtc cacggcctcc tggtcggtcg cgtccattcc
     2701 cgcaagtgcc gcggcaatct tcccgttgac gccctcgact gcctttttca cacctttccc
     2761 gcggtaccgg tccattgcac cgtcgcggag ctcgactgcc tcgtgggtcc cggtcgacgc
     2821 ccccgagggg ctcgctgccc gtcctgtcac accgcacgcc agtacgacgt ctgcctcgac
     2881 ggtcgggtta ccccgggaat cgaggatctc ccgggcatgg acctttcgta tcgctgtctt
     2941 atccatcgtg atctcctctc acatgtacgg tgccgggaaa gaataattcc tcctgccacg
     3001 ggagaacccg gcaaggattg caagggattc aaccgccctg gcggtatatt ccagtgtcgg
     3061 cgagccgcca aagaccgacc ggacaaagcc gccggacggg tggccgcact cccggacaaa
     3121 ctcccggcag gcatcgatgt gccggggcgc cacaccgaga aggagggcga gtcggagacc
     3181 cgcatgcacc tgctcgagga aagcgggttt gcttcccggt cttcccagga aaccgaattc
     3241 cgggtccccg cacgcattca tgaaagagac cgtcccgccg tcattgcacc cctgcccgag
     3301 gaaagcgagg atctccagtg ctatccgggt atcctgcagg gtgggaactg gtaccccgaa
     3361 cccccccgtc tccgaacgaa aggaaagtac ggttgccgtg accgcctccc ctgagtccgg
     3421 gggtattttt actccataca ggtcagcgag tgcagcccac gcacggaggg gttcgaagag
     3481 ggagagagac tcgatgaccc gtgtccgcgg gtcgggacgg ggcagggacc ggagaatgta
     3541 cccggaaggg tcgtggaatg gctctgcatg gagcatgcgg agagcccatc ctgcaaagag
     3601 ggcacaggat agtgatggat aggatccatc cgggtactgg agattttgga gaaaccggat
     3661 ggtcttttcg tcggcatcca tctcaccgag gaaggagagg attcccagtg caaagcaggt
     3721 atcccccgca ttcggctcgt cgagcctgta gaaacagtat cctcccgacg ggcacctgcg
     3781 actcctgacg tattcaaccg tcccggaggg caggtcagga aaccgggccg gcaccggtcc
     3841 tgcaccctgc catgtcatgc tcatccgggg gtgtcagaaa gggcggcgat gagttcctga
     3901 agggtccgcg atgcctctcc caggaaccgg accctctccg cgatctcctc tgcccgctcc
     3961 tttctctgcc tgtaggctgc ggcgatggcc ccatgggtcg catcgatcgt ccgggcaagc
     4021 tcctcgtcga tctcgcgtga aaagatcctg aacgcggcat ccacgttctg cagggtcgcc
     4081 cagcggaggt tctcgacatt ctgaacgacg agtgagtgaa tctcccgtgc aatccttccc
     4141 cggagacgct tttcccgcat tgcacggggc agcgccctgt caacgaggtc gggtgatatc
     4201 aggccgagca tccccgacca ggtcctccgc gagacccagt agggctctct ggcaaggacg
     4261 agcggccccc cgggtgaggc cctgtgatgc ggtatctcga agattgtgga tgccgcagcc
     4321 ctgatcgact cgctcagggc ctcggctttc tcccggtggg ctgacaggac cgcaaccatc
     4381 tcgcgatcga acctttcggt gacttcccca agcgtgtgct cgaagtagac cggaatctcc
     4441 tgggcgatcg cagcctcgac gttccgggga tcgggatccc ctccagttga catcgcgcga
     4501 gaggctacac cctgcaggtg catttccgcc tgctccctga taccggcgca cacctcctcg
     4561 agaagggcga ccacgcgcct gtggtcaccg gaaagaacat cctgcgtctg ccggcgctgg
     4621 cgctctgcct cgtccacctt attttggaaa agggacaact ttttttcgag atcggcaatc
     4681 ggcatcccca gagactttct ctcaaggctg acgcggagcg atgcgtcgtg caggacatcg
     4741 agtgccttcc tccggacagc ctcggaaagg acccgcgtct tttcacgggc aaggaagtcg
     4801 acgaggtgct ccgtaatggc cgaaatcccg ctcgaggcaa ggagcgtctc gtctcccgtc
     4861 agcctggcga ggagcgcctg ctttgccgag accggaaaga tcttttcttc cggggctatc
     4921 cctgcctttt cggagaggac ttttctgatg aacgcgatga ccgtctctct ctccggcatg
     4981 gtcaggtagt cgaccttgtt ctggacgaag aagatgcagg ctaccttctc ccggacgtgc
     5041 cggaggaaat cgacctccac ctcggtgatg ggagggtcag ccgagaccag aaagagcgcc
     5101 gcgtcgcact gagggaggaa attgagtgtc atctcggtat tgtgcctgtg cgtggaacct
     5161 atcccgggcg tatcgatgag gacgacgtcc cggaggatgc gggacgggtg ggtgatctcc
     5221 acggagctca ctcccttcct gttcttcgga ttcgcctcct cggagacata atcgagcagg
     5281 atccggttca tctcctcagg cgactggcag gggatggtcc catcttttcc ctgttccagg
     5341 aaatggacct tgacggtccg ctccgttccg tgccggatga aagtagggat ggcggtcagc
     5401 gggatgacag aactcggtag gatgtcttcc ccgagaaggg cattgagcag cgtgctcttc
     5461 ccccgcttga actgccccag cacagcaagc tggaaccgcc cctcggagag gcggtcacgg
     5521 aggccggaaa gtgctctttc ctgcggttcc atcgcaggac cgaggtcatg gaggatggaa
     5581 atagccctcc cgaggaggga ggacaggtcc ggtgtggcag ccgggggaaa ggccgggtca
     5641 ccatttcggg gagaaacgga tgttatatcc tgtgcggggt cttgcatgat actccttcct
     5701 gtaccggggg tttcctgata caaatcgagg ggtttgggta ggagttatca gcagtgcctg
     5761 cggttatatg gtgaactcca tcaccatcac aacaactgtt ccatatctcc tgcaaggcac
     5821 aaaaaaattt cctcgtgact tattggatcg cctttccttg ccatttttca tccctgcgtt
     5881 ttccccgata cccgggactg cctgttctca atgaaccccg cgcacgatac gagagtcccc
     5941 ataaaaatca ggcggttttt ccttcccggt ttgtgaatga ttcctggttc attcacgcat
     6001 ctcccgggtg aataatcccc cgaaatgggt ctcccactcc ttcactacct ttatccgtta
     6061 tgtgagagga ttacatcact ggggattgat gctttggggt ccggtacgat ggcgtgtcat
     6121 gatcttttca gggagtccct accgtccggc gatttttcgg gcaggtatcc gatacacctc
     6181 cgggcaacgt atccgcgacc cccaaaatca tcgcaaagag ggtataatgg tccggagagc
     6241 ttcccatggt agaccccgaa aaagagagcg gcaggaggcc gggtccctcg tattcattct
     6301 cccaccagct gcttttctgg atggtcatcc tcatcctcgt ccttgccatc ggtatcacct
     6361 attttgatta ccggcaggca gaggagacct accagaagaa tgcccgcgcc atggaggaac
     6421 tgacggaggc caacattgcc gggaccatta tcgtgatcga ctccgcgtac gaaatgtacg
     6481 acagctcgct caacaacgag atgaagaacg cattttccct ttttcaaaag gagtacgagc
     6541 gatcaggcaa tgatcccgcg aagatggacc tcgatgccct gaaagaggcg ctcggcaacg
     6601 agatggacct ctacatcatc aacgagtcca tcatggtcga atacaccact gatccttctg
     6661 accttggcct cgacttcagc cagtggccct atgcgtataa ctacctcaaa gacctcttac
     6721 agagagacgg ttttttccct gaccggattg ttcatcacgc aacgtcaggc aaactggtca
     6781 aatatgccta catgccaacg ccggaccacc ggtacatcct cgaactcggg ctctcgggca
     6841 aagcgcttga agagagaccc catatcaggt accaggattc cctcagggcc attgccctca
     6901 ataacccgaa tgttgtcagc tacagggctt acgatacact gggaagggtt atcgggaata
     6961 atacctcatc tgcgcaaagc actccaccct tcatccggca ggtcatcagc gaaaggaagc
     7021 cgctcgagat cgttgatccg aataacaaca ccctgacgag atacctcttt gtcgatctca
     7081 ccaaccatag ttatgtttcg gatgtgagct ggatcatcga gctcgtgtac gaccagtccg
     7141 agttgaagga ccagctcaca acacttctcc tcaaccacgc cctggttgcc ctccttgccg
     7201 taacgttctc tatcgttttg gcaatcgttc tctcccgccg cctcacgcgc cccattgcac
     7261 agatggtcca tgacatcgat accatctccc ggggcgacct cgagtaccct ctcgccccgc
     7321 ccaggacgac cgagttcgaa agaataaccc ggagtgtcac ttcccttgtt gcttcactcc
     7381 ggggaatgat ccggcagctc cagcagaccg aactcgaact tgtcaggaag ggggagaatt
     7441 accgggcagt tgtcgagaac cagacggaac tgattgcccg gttcctccct gacgggacgc
     7501 acgtcttcgt aaacgaagcg tactgcaggt acttcggtct gccatggccc gatatccttg
     7561 ggcacaaagc ctggcccaaa gtcccgccgg aggatgatga actcattcgc aggcatttct
     7621 cgtcgctctc gccggagaac ccgactgcaa ccatcgagca ccgggttatt acacctgatg
     7681 gtcaggagcg ctgggtccag tggaacgaca gggccatctt tgattccgac ggaaatatca
     7741 tcgaatacca gtcggtcgga cgggacatca ccgagaagaa acacatggag gaggacttaa
     7801 ccaggagcga acagaaattc cgggaccttg cgggtcttct cccgcaggtt atcttcgaaa
     7861 cgggccccaa aggagagatc ctgtacgtca ataaatcagc ttatactatt ttcggctaca
     7921 cgcccgagga ggtgcggtct ggcgtggaca ttttcgatgt catccacccg gatgaccgcg
     7981 acctggcggc cgggaacttt gcccgctccc tccaggggga aaagatcgat ggtgccgagt
     8041 accgcatggt acgaaaagac ggatcctcca tgatgggaat ggtctattcc tccccgatcg
     8101 agagcgacgg caggatcacc gggatccggg gtatactcat cgatatcacc cacatcaagg
     8161 atgtcgagcg cgacctccgg aacctcaacg aggaactcga acgccgggta agggagagga
     8221 cgcaggacct tgaatcggct gtccgggaac tcgaagcgtt ctcgtactcg gtctcccatg
     8281 acctgagggc acccctgcgg gcgatcgacg ggttttcctc gatcatcctg acccattatg
     8341 acgaggcact tcacccggaa atcagggaac tcctccggaa gatccggaca aacgcccaga
     8401 agatgggaga cctcatcgac tccatcctga acttctcccg catgtcgcgc cagcccctct
     8461 cgcggcagac tgtctatccg gcccgcatcg tggccgaaca gctcgcccag ctccggggga
     8521 tgcaggacgg gagggacgtc acggtgcgta caggcgatct tcccccctgc gagggggacc
     8581 cggtactcct cacacaggtg ttccagaatc tcctctccaa tgccttcaag ttcacccgga
     8641 cccgtaagca tgcggagatt gaagtgggat ccgagaagca ggacggaaag accgtgtatt
     8701 atgtcaggga caacgggatc gggtttgaca tgaaatacgc gtccaagctc ttcacggtct
     8761 tccagcggct cgtggacgaa aaggagtacg aggggacagg gatcgggctg gcgatcgtcc
     8821 agaggattat ccagaggcac gggggaaggg tctgggcaac aggcagggta gggaaaggag
     8881 cgacgtttta cttcacgctc gagtaagaca ggatacgtgg actattggaa tggggtaaac
     8941 aggaaaattt catcatccac ctccgccaat tttcttctgg cgatgaagtc cgccgggaca
     9001 aatgcgtttt tcgctgatga cttctctcct ttccccctga cgtgatgata catggtggtc
     9061 gggggaacaa ggaacacctg gtgaccacta aaaaaaggaa tttctccggt aaaagggaat
     9121 gaatggatga ttgtggttgc cggggagtga aaattcccat ggagggatgg ttgggggatg
     9181 gtccggaccg ataccagtat caggttgatg gggctgctcc ttgacggaaa acccgtcacc
     9241 gacaagcagc tggcagacgc gatagggttt aaaaaccccc ggaatattgc caggcacctt
     9301 gagtcattcg catcatcagg ttacatcagg atactgccac aaacggggag agacaactat
     9361 cgattgttcc agcttaccga taaaaaagat gggctcctca agctctacca gtcacgattc
     9421 taccgggtcc tgcgcccccg catcagggag attgactggt ttatcgatca ggtggcagcg
     9481 ggcttttctc cccttcccag ggatcttttt aatctcatcc gggagatgat gaagaagtcc
     9541 cacaccttct tttccctgat tgccggccac tccagccatg accagctcct ctcttcctac
     9601 tcgctctacc tctttccctg ccgcctgatg aatcgtgacg accccctctt ccaagcctgc
     9661 tacctttatg cccagctcta cgccgaatca attacgcggg atatccggga ggggggtcta
     9721 tccgagggtt tcctggaacc ccttgatgca atccaaaagg tcatcctgca actcggaccg
     9781 ccggcaatca ccgactcttc ccgggatcat cccgggtaca aagggctgca ttgtactgga
     9841 caaaatccct tgcaatcttc ctgaccagag gagggggatg ccgggcgagt gatgcaatca
     9901 tggtcccggc ttgcggacct ccgatgcggt ccagggccct gactgcctcg cggatgatgt
     9961 catgatcatt gtctgtcacg attattttct caggtgccaa aacagcttcc cccgacccag
    10021 gcctcccgat tacttcgatc gcaatcatcc ggtgctccct gacgggatga gaaagggcag
    10081 aaagcaaccg ttcccccccc cggtcagtat ttcctctgat gcaggatcat gcccacactg
    10141 cgggcaggta tttatcagcg tggtgccatg ataccggcag cggggacaga actacgtagt
    10201 cacccttttc acacctccct gcatctctct ttgtccgtga tctcctccga caatgtcctg
    10261 cctttcaaca aaacgagtga tgtatccatc aacctcaaac aggatcccca atgactgatc
    10321 acatatccgc accaaaaaag cgggaacaga acgggagaaa acctctcatc ctcccgccct
    10381 ttcaattctt ccagtttcaa cagttctccg gagccagacg aatgcagcca gtgcacctgc
    10441 ctgcatcacg atacagtaga ggacgagcag ggcgagattc agcccataga gcgcacccat
    10501 aacgacactc ccggcaaacc aggcaccccc gtagagcgta ttgaacacgc cgtagacagt
    10561 ccccctcttt cccacggacg tcaggtccgc gagtgctgcc cgaagaacgg tctcctgccc
    10621 gcccatggag agcccccaga ggatggatgc tgccagcgct ccggtgtatc ctcccatgaa
    10681 cgccagtgca gcaatgggga tattgatgac cggcacagcg acaaggacgg aaagtcctac
    10741 ccggtcatac acccttccca tggcgagggc aaagagggcg tcggttgcca tggctatcgc
    10801 gtaaaagacg ggcacctgtg cttccgggac cacggatgca gcgctgaaat ggtaggccat
    10861 gaggggaaag accgcaaaac ccgccatggt cagcacggtg aatgccccat acgggcgcat
    10921 gacccgggag acctgcaacg tcccgtcccc ggaaatcgcc cgggagtcat cctcgaactt
    10981 cacggggtcc ggtactgaaa atcgtgcata gaggagggct gccacaagga ggacaaaggg
    11041 gatggcaagg agggcaaagc ccgtttcata ccttcccgag aatgcaatgg agactgcaaa
    11101 gagcaccggt ccgatgactg ccccgacctg gtcgagagcc tcgtgaatgc caaaacccca
    11161 gccgcggccc acctgcttcg aggcatggga gaggatcgcg tcccgtgccg gggaccgcag
    11221 tccctttccc acgcgctcga cgaggatgaa gatcgcagcg acttcccatg accctgccag
    11281 gacgaggagc gggacggccc cgaccatgag gtagccgacg atggtcaggg cccagtacat
    11341 ccccgtcctg tcggagatgt accccgagag gagacggata ccataaccca ggaattctcc
    11401 aaggccggac acgattgcga ccgtgagggc cgatgcaccc aggagaagga ggtacgggcc
    11461 ggttacactc ctccctccct cgtaaacgat gtccccaagc aggctcacga cacccagaac
    11521 gaggatgagc cggaaagcga tggccctgct ggtgactgac tgtataccca tggaatcacc
    11581 ggacttcagg atgcaacctg acaggtcctt ttggtaccgg gtgagggatg aacgacgaaa
    11641 tactttctcc aattgcaggg ggggactccg gaacgactgt ttcccccctt taccgcccgg
    11701 ttcccgtcaa tgcctcttgg gatgcttttc aggggaaccg cgcccggagg gaggggcccc
    11761 tatcccgacc ttcccggata tggttctgcc tcgatccggg aaattttcca aacatttaac
    11821 ggatcgggag aaaatacagg tcgatacagg atcggagaga tccactgatg cagcaccggg
    11881 ttctccggat ctgtattctc atgggaaagg agacccttct gggggttcgc gggtatgact
    11941 gaatagtacc cgttggtcat aaaccggttc tccgccactg accgcccttg tgccggactg
    12001 ctgcatgcca caaccaacgc gatgacgtga tgagataatg gcaacaatcc atgtaaaccc
    12061 ggactcctgc acccggtgcg ggatatgcgc catcgtatgc ccgatgggaa tcgtctctgc
    12121 accgggtgaa cagacactgc ccggtgtccc tgacgccgca tcggccctct gtatcaggtg
    12181 cgggcactgc gaggcctact gcccggcaca ggcactcctc ctgtgtgacc gcgcagatga
    12241 aaaagtctgg attccgcagg gcgcggggtc agtcaatcca caggatctcg ggatttacat
    12301 gcggaaacgc aggtcggtgc gcaactacag ggacgatcct gtccctgcgg agaaagtcag
    12361 ggaagtcctc gatatcgccc ggtacgctgc aaccggaggc tgtggacagc ccgttgaatg
    12421 gacggtcgtc ctcgaccggg cgagggtaag gcggatcgcg gagctcacga tcgagtggct
    12481 aaagactctc cgtgattccg accacccgat gcgcggcgtt atcccggtcc ttgtcggggc
    12541 atgggagagt ggccgcgatg tcatctgcag ggacgccccg cacctgctct tcgcccacat
    12601 cccggaggaa aacccggttg cattcatcga cgctgtcatt gccctcacgt acttcgacat
    12661 cgcagcaccc gcacacgggc tcgggacgtg ctgggccggg ttcgttgcca tggccgcggc
    12721 cgcgcatgcc cctctccgga aagagatcaa cctccccgcc gggcggaaag ttgcctatgc
    12781 catgatgttt ggttaccccc ggtatgcggt gtatggcatt cccccgagaa aaccgcttgc
    12841 ggtcacctgg ttgtaatccc ggcgcaggaa gtttcatctg aatggaaatg acatcgtgag
    12901 gacggttgca gagggtctgc agagatgaaa agcataaaaa agccagacga agcagaagag
    12961 gttttccggt caggtatcac ccgttcttca gcggtttttt ccacgttcgc agaagaaaac
    13021 gggctgcctg cggatgttgc gcggaagatt gcatgcgggt ttggggcagg tgtctcgaaa
    13081 acggggaaca tgtgcggagc tgtctcggga gcaatccttg ccatcggctt aaaatacgga
    13141 aaatcggaaa ggacggatac agcggcgaat gaaaagactc gtgccctcgt ccgggagttc
    13201 atagctgaat tcatccggcg gaacggctcg atcacctgca ccgagctcct cggttacaac
    13261 ctggccaatc cggacgagta tcagaaggct gcagaatcgg gtcttttttt gtcacggtgt
    13321 ccccgttacg tcagagatgc agcggatatc ctcgaacgta tcctctgaat gcccaaaaac
    13381 cccggcggga atgcccgggt aataccattt ttcctgccct tcgctatttt ggcagagacc
    13441 cgtgattatg gagaggttat caccctcccc atcctctcac cgagaaggtg ttttcctttc
    13501 cctggggatg ccaagcagcc ggtgcctccc ttttttcccg gcaatgcagg cggattgttc
    13561 cgtccccgtc ccccatcgcg ccgatatccc gattcctttc ggggatcacg ggttcccggc
    13621 cagcagagaa agacaggttc cggggatccg atccggatga aaaaagaaat gatgaatcct
    13681 tccctatcac gtggcatgaa aaccctgtcc tgtttgggac ttgccatcac gctcctcctc
    13741 gtgcttgccg caggatgtac ccattccgaa aattacaccg tcactgaaac acctgccccg
    13801 ataaccggca atgctgaaat gaccggtgcc cttgcggccg tgaccgcaga gatacaggaa
    13861 tcactcaacg acatcgacaa ccaggtctcg ggtgcagcga ctgcactcgg gaagaccggg
    13921 atttcaggcc ctgcagcaga agcaatcctg gaaagggctg cactatccca ccctgccatc
    13981 caggacatca tcacctatga caccggcggg atcgtccggg ctgcagaacc ggggggtgca
    14041 cgcgacctcg tcggacggaa ccttaccggt caggagatag tgagaaaggc actgcaggaa
    14101 caaagacccc tcatgagcga tctcttttcc ctcaccgagg gaggagccgg agccgtgatt
    14161 gcataccccg tacatgcgca ggacggcaca ttcatcggtg ttgtcagcct ggcattttct
    14221 ccccctgccc ttgtcacgcc catcgcaggc gatgcaacca gcgggacgcc attctccgtc
    14281 atggtcacgg agacgggtgg acgcatcctc tacgatgcgg acccggccca ggtgggaaag
    14341 gagaccttca acgagaccat gtttgccggt ttcccggaga tcctcgatat cgcccggaat
    14401 ctgcctggta acaggacggg acacgcgacc tattcgtttt cgggcagcgg ttcaaagaat
    14461 gttatcagga aggaggcatt ctggtcaact gtcagcctcc acggaacaga gtggcgtgtc
    14521 tttgttatca gggagatctg atcaccggga ctcgtcttcc ccctcctttt ccgaccggct
    14581 atcacatcgt ggttttcaca ttgtttatcc ggtcacgcgg caggcatggg gcggttacca
    14641 tgaaaatggc tttgctgttt ccattctttg tgcctgtatg ctgatgagaa ccatgcgatt
    14701 tttataagaa atagccggaa attcgaaaaa gcggttcgtg aatggatgac acgagccgca
    14761 ttgtgtactt tttttcccgg gaaaaaggta tgattcctgg cctggattga gaggagtaag
    14821 gaggtctggc gaggtttaaa cctcttttgc tgcaagttcc acgtcctctt ccttgatggt
    14881 cttccggccg gcgtgcatcg caaacttgtt tgccttttta acgagttccg cgatgtattc
    14941 ttctgactgt gcaacgagtg cagctgcggc gtcacttccg acacgttctg caccactctt
    15001 cttggcaatc ctaacgactg ctgcaagagg taaatctgcc accttgatca cctcatgtga
    15061 taaggggttt aaatagtatt tatatattgc tgttaaaccg gcccaaaatg gggtgacatc
    15121 gatgttcaaa cggatattcc gggtgattcc ggaggggaga tcaggggctg tcgataactt
    15181 ccggaaaaga ggatcccgta aaactggtcc tgacgattcc ggcaacgcga atggatttcc
    15241 ggcaggctct tcgccaggca taccggagtc aaaattacga agcagtaact ttttatgccc
    15301 ttctcccggt gtagtggtac tggcctgtca caggtgcatc atgaaaagga tagtcctgtt
    15361 aaccgttttc atcggtattc tcgccgtcat tgccgttttt tcggcgggct gcctctctga
    15421 aaaaaacccg gccgggacga cgggcggaag gccgcagtac accattggtg tcgataccga
    15481 ttacagaccc ttcgcctaca tggacgagga ggggaatatg acggggttcg atatcgatgc
    15541 cgcccgctgg atcgctgccc gaaaagggtt tgacccggta ttcgttggct ttgcctggga
    15601 tgatattatc cctgcgctcg agcaggggaa gatcgacatg atctactcgg ggctgacagt
    15661 tacgcccgaa cgggaagaga gggttgattt cacgcggcct tactatacca ccaatcagag
    15721 tgttgcagcc cggaccggat ccaatgtcag catgcaggac ttccatgccg gcaggctccg
    15781 cgttggtgcc caggccggat cgaccggggc tgcgtgggtc gcggagaacc tcgccggcgc
    15841 cgggctcatg cctgcagaaa aactcgttct ttaccccgat gtctcttcca tggccgcggg
    15901 cctcgaaggg ggagcagtcc aggcgattat cggggatgct cccccgctga tccttatggc
    15961 aaaagaaaag cccttttcga tcatcggcga gatcccgacc agggaaagat acgcaatcgc
    16021 tgtccggaaa ggggataccc ctacacggga gatgatggac gatggcctct cccagctgat
    16081 gaaagatccc tcgtggagcc tgctccttga aaagtatggc cttggcgggg ctggcagcgg
    16141 gggagtcccg ggccgcggcc agccggaaac tacggaagaa ctcaaagact acgtggacga
    16201 ggcagcgtcc tttgcgttga gccatggcag ggatgcggcg attgccgctt tccaggatgt
    16261 gaacgggccc tttgtcagcg gggacaccta cgtctatgcc ctcgattatt caggtgttgc
    16321 ccttgctctt cccttccagc ccggcatggt gggcacgaac ttcctccccc tgcgggacgc
    16381 aacaggcaag ccttacacgg atatcgagat ccggcttgcc agggccgggg gtgggttcat
    16441 cctgtaccac tacccgaaac cttccgagaa cgggacgagc aggctcaaga tcagctacgt
    16501 ccggccggtt gacgatacct attggatcgg ggccggcatc tacacggacg aggatgcact
    16561 catcgacccg gaactccggg aattcgtagc caacgcacgg gaattcgccc tctcgcacgc
    16621 acgagacgat gcactggcag cactgaatga ccctgccggc ccgttcatca acggtgacct
    16681 ctacgtcttt gcttacgatt acaacgggac ggtactcgca tggccgtacc ggccggacca
    16741 ggtcgggaaa aacaggtaca acgagacaga tatgatgggc tcctaccacg tccgggagat
    16801 gattgcaaag gcacgccagg gcgggggaat ggtggactac tattcaacga acccgtttac
    16861 caacaggaca gcgttgaagg tcagtatcgt tatggacgtg gacggttcat ggttcatcgg
    16921 agccgggagg tacatcgaac cggggccgtt ccgcctcgtc tcctgacatg agcccccggc
    16981 atacccgacc tcctctttta cttctccggc atttgcccgg g
//
LOCUS       DAOOJU010000032        16378 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_3414_length_16378_cov_16.223305, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000032 DAOOJU010000000
VERSION     DAOOJU010000032.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 16378)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16378)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16378
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3414_length_16378_cov_16.223305"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1178)
                     /locus_tag="PK679_07625"
     CDS             complement(<1..1178)
                     /locus_tag="PK679_07625"
                     /EC_number="4.1.2.43"
                     /EC_number="4.2.1.147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,6,7,8-tetrahydromethanopterin
                     hydro-lyase/3-hexulose-6-phosphate synthase"
                     /protein_id="HPC55864.1"
                     /translation="MYHIGEALVGEGPELAHVDLILGDKDGPVGTAFANALSQLSAGH
                     TPLLAVIRPNLMTKPATLIIPKVTLRKGSQIREMFGPVQAAVAKAVADAVEEGAFGDR
                     DLESLVILASVYLDPEASDYNRIYRYNYGATKLAITRALDNFPDQKTLLYEKDRAPHA
                     VMGFKVQRLWDPPYLQVALDLVEMAKVRSVLTELPQNDHLIIEAGTPLIKRFGLSIIS
                     EIRKVRPSAFIIADLKVLDTGNLEARMAADASADAVVISGLAPQATLEKAIAEARKTG
                     IYSVIDMLNVADPVRVIKGLKAKPDVVELHRAIDTEGSAHAWGDIPALRKAAGGRLLV
                     ATAGGIRVDKVRDALSAGADIVVVGRAITASKDVRSAAELFLEQLNKEEIDQFRVMTD
                     "
     gene            complement(1249..2040)
                     /locus_tag="PK679_07630"
     CDS             complement(1249..2040)
                     /locus_tag="PK679_07630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HPC55865.1"
                     /translation="MPAELHIVDAFTSTPFCGNPAAVCITGEERESSWMQNVAFELNH
                     PETAFLRRLDDSWELRWFSPRAEVDLCGHATLASAFVLWATGREEGNSSIRFLTRSGP
                     LAASMDSREIALDFPSVPVDACDPPEGIEDAFGCPVVFPGRTRFDLFFELPSATDVCT
                     LDPDMDALAALPARGIIVTAPSDTPDYDFVSRFFAPSIGIPEDPVTGSAHCSLGPYWA
                     GRLSKASLSGFQCSRRGGAVRVTVKGERVILAGNAVLVVSGRLLT"
     gene            complement(2114..2273)
                     /locus_tag="PK679_07635"
     tRNA            complement(join(2114..2149,2236..2273))
                     /locus_tag="PK679_07635"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2237..2239),aa:Trp,seq:cca)
     gene            2378..4078
                     /locus_tag="PK679_07640"
     CDS             2378..4078
                     /locus_tag="PK679_07640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HPC55866.1"
                     /translation="MDAGSYDCGISDKPLLGLTVGEMFSQVARKYPDTEALVSVHQGI
                     RYTYRDLLRKVEELGKGLMAIGVEKGDRVGIWAMNHAEWVVTQVATAKIGAIMVNINP
                     AYRTYELEYVLRQAEIQTVILQDRFKTSDYVGMFLEACPEVAASRPGHLHTEKFPFLK
                     NVIFMGENAPDGMFSWDEINHMGHDVSDDELFAREESLSFDDAVNIQYTSGTTGFPKG
                     VVLSHHSIVNNGNIIGDGMNFTEKDRLCIPVPFYHCFGMVLSNLACMTHGSTMVLPGP
                     TFNAGEVLQCIEKERCTALHGVPTMFIAELSHPDFSRYSMETLRTGIMAGSPCPIEVM
                     KEVNRKMHMSEIVIVYGQTETAPGITMTTTRDPLERRVSTVGRVFPHTEIKIIDPKTG
                     RIVPRGEVGEICARGYCVMKCYYNNPSATHATLDADRWNHTGDLGTMDAEGYVKIVGR
                     LKDMVIRGGENIYPREIEEFLHNHPKIADVYVIGVPDEKYGEELMAWVMVEKGETMTG
                     EEVREFCRGKIAHYKIPRYVKFVTEFPMNISGKIQKYKMREISIRELGLENVSKIETA
                     "
     gene            complement(4175..5485)
                     /locus_tag="PK679_07645"
     CDS             complement(4175..5485)
                     /locus_tag="PK679_07645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HPC55867.1"
                     /translation="METDLSGRGSLLIRDVRLNGERVDIFADEQGIIAAVGSDVGRTE
                     GRGADRVIEGNGATALPGLVNTHTHAAMTLFRGYAEDMPLQEWLSGKIWPIEAHLTGE
                     DVYWGTKLACLEMIRSGTVAFSDMYFFMQDAARAVAEAGLCAVLSYGFIDLFSGEKRE
                     AECRNTEEFVRFVRGLKNPRIKAAVGPHAVYTVSKEGLSWCAEYSESEGIGIHIHLSE
                     TEKEVTDAVAQWGKRPPAILDECGILTPRTIAAHCCWLDRDECTLLARRGVHVSHNPV
                     SNMKLATGRAMPYHWLKEAGASVTLGTDGCASNNSLDLLTDLKFAALLQKFAWNSPTL
                     LPAEEALAMATSAGARALGFGNGRIAPGEPADIILLDSRAVCNTPAHSVTSNVVYSCP
                     GSAVMTTICHGSVLMHDRTVPGGEEILREAARAARALVERVRES"
     gene            complement(5499..6170)
                     /locus_tag="PK679_07650"
     CDS             complement(5499..6170)
                     /locus_tag="PK679_07650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTAP family purine nucleoside phosphorylase"
                     /protein_id="HPC55868.1"
                     /translation="MLGIIGGTSLLYAQIPPLEERVVHTPFGNCEVRTGDIAILLRHQ
                     RSLPPHRINYRAHLAALALLGVDRLVLIGSSGSLKKEIQPGTLMIPTDYFSFAPVPSI
                     HDHAICHVTPGFSPRLLESLRAIVPGARFGGTYVQTPGPRIETMAEVRALASVGDIVG
                     MTVASEATLATELGMEVAAFCTVDNYANGLSDETFTYEGLLESSAAFAKRNEEILSRI
                     IRGLS"
     gene            6299..7450
                     /locus_tag="PK679_07655"
     CDS             6299..7450
                     /locus_tag="PK679_07655"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HPC55869.1"
                     /translation="MGRFAIVDDDRIRAGECTDIYFERAVAVLEKSGHSPDVAMEVTA
                     SDLPGGWGIVCGTEDVVSLCEGLPLSLDAMPEGSLFFPREPVLRVRGKWPDIARYETA
                     ILGFLCHASGIATAAARVRALAGDRQVFSFGSRRQHPAIATMVERSAWIGGVDGVSNT
                     CAPPGVPLAGTMPHAFVMCYPSPEEAFRAFDRHAPPEVPRIMLCDTYCDEKQESLLAA
                     RCGARGVRLDTPRSRRGDMRAILEEVRWELDAAGYSDVMVFLSGGITPGDVAQFRDIA
                     DAFGIGGAIANAPVLDFSMDIVEKDGTGCAKRGKRSGAKQVWELPDMRHVVLPEGRKG
                     PQGADPLLVPMVRDGEVVFRQGMEYARARVLRRIPAIKELVERENRKER"
     gene            7625..7696
                     /locus_tag="PK679_07660"
     tRNA            7625..7696
                     /locus_tag="PK679_07660"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7657..7659,aa:Ala,seq:ggc)
     gene            7768..8397
                     /locus_tag="PK679_07665"
     CDS             7768..8397
                     /locus_tag="PK679_07665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="HPC55870.1"
                     /translation="MAIKEWLIPQDEVFFTLFERLAAVVVLASYRIVDLVDDYTNVRE
                     KVHQIEQLEHEGDKITHEIYEQLNQTFITPLEPEEISRLASALDDILDYIKSTATRMY
                     HYRIQETDPHMLELAKLIQLSVVELEEAVKGIRTMKNPRQIEQRCIEVNRLENLADDA
                     LHAAYDDLFRTDDAITIIKRKDIYEYLEDATDRCEDVANVLSDIAIRHS"
     gene            8407..9588
                     /locus_tag="PK679_07670"
     CDS             8407..9588
                     /locus_tag="PK679_07670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HPC55871.1"
                     /translation="METLLAIGIFLALLFNFVNGLNDAANSIATVVATRVLSPVRAVA
                     MAAFFNMAGPFVFTTVVAKTIGKGIVDPGFLIPEVIVIGLGSAVLWVFLSSYAGIPIS
                     ASHALVGGLIGSALAWGGIGSVLWPSMELFEKTLAVFIAGGVTGALLLSYAARRKHEE
                     HWVEYTGLGFLCGASLLLPPAIVSGVLPLKGILAIIVFIVVSPVLGLVSAYLLGMVVI
                     RLFRNSPAGKMNALFSRLQVFSAAFYSLGHGSNDAQNAMGVITALLFAAGILTEFVVP
                     PWVIIVSGLAIALGTFLGGWRVVETMGRKITKLRPYQGFCAETGGGVVLSFVTAFGVP
                     VSTTHAISGSIMGIGATRGYSAVQWGIVRKIVTAWILTIPLTATCGYIAFLVFRVVFS
                     F"
     gene            complement(9566..10243)
                     /gene="nth"
                     /locus_tag="PK679_07675"
     CDS             complement(9566..10243)
                     /gene="nth"
                     /locus_tag="PK679_07675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HPC55872.1"
                     /translation="MDRERAGRVYSVLEDLYGDPGSPRTFLRFENPFQILILTILSAR
                     TTDRSVNAIRDRLFSRYPEPKDLANADPRDVEDIIHPLGFYREKAQNIIKTSRALIER
                     FGGRVPDRMDDLLTLPGVGRKTANIVLDHAFGIHDGVAVDTHVARLSRRLGFSSGKDP
                     ARIERDLMALFPQSAWGNLNYLLIRHGRTTCTARKPSCTTCPLGSLCPSADNPSEGEP
                     VRRKKPP"
     gene            complement(10247..10321)
                     /locus_tag="PK679_07680"
     tRNA            complement(10247..10321)
                     /locus_tag="PK679_07680"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10283..10285),aa:Pro,seq:tgg)
     gene            complement(10358..11080)
                     /gene="pyrH"
                     /locus_tag="PK679_07685"
     CDS             complement(10358..11080)
                     /gene="pyrH"
                     /locus_tag="PK679_07685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HPC55873.1"
                     /translation="MVRIVLSLGGSVLFPSLEAHTLLSYAPVLQRLCRQADIAVVVGG
                     GGEARRYIGVARECGADEASCDEIGILVTRLNATLLLAALGDSAYRKVAQTPGEAVAY
                     MGRKKIVVMGGVTPAQTTDAVAAVLAELSRADILVNLTSVDGIYTRDPKADPSARRFD
                     RMTFGELLDIVGSGGLEAGSNTVLDIVAAKVISRSGIPLLVLDGREPGLLEDVLAGRK
                     RAGTLVCAPGKEPVPLLRAPSP"
     gene            11079..11285
                     /locus_tag="PK679_07690"
     CDS             11079..11285
                     /locus_tag="PK679_07690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55874.1"
                     /translation="MPIIHFSIFHIYLLKAMEHCPACGSREIYPVAGGCIGQIYRCKA
                     CGYRGSLVVECDGDDEPRRDSNNG"
     gene            11343..12359
                     /gene="amrS"
                     /locus_tag="PK679_07695"
     CDS             11343..12359
                     /gene="amrS"
                     /locus_tag="PK679_07695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system radical SAM enzyme"
                     /protein_id="HPC55875.1"
                     /translation="MHRALRWSPEGQEGAVRCSLCPHGCLIKPGKTGICRVRENREGE
                     LYALTYGRVSAEAVDPIEKKPLYHFLPGTLSYSLGSVGCNFHCAHCQNWHISMADTEM
                     PGLRDLSPEEGVRRARQAGCASISWTYNEPTIWHEYTLDMGNLARKEGLATVYVTNGY
                     ITEEALRELSPMLRAYRVDIKAFSEDFYRKVCGARLQPVLDSAVLARELGMHVEVVTL
                     VIPGQNDSPQETGALIRWIRDNLGEDTPVHFTRFHPDHRMRDRGATPVAVLERIYRQA
                     REEGLRFPYLGNVSPHPWESTYCPSCGALCIERYGYSVFFRELSGESCSRCGERIPYV
                     RAGG"
     gene            12340..12858
                     /locus_tag="PK679_07700"
     CDS             12340..12858
                     /locus_tag="PK679_07700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mut7-C RNAse domain-containing protein"
                     /protein_id="HPC55876.1"
                     /translation="MSVPEGEATGQTRFLADRMLGTLCRYLRFMGYDTVSATEMAEGN
                     SREDTVLLSRARTEGRILLTMDRELARRGGSDAVLIEEKNVMDQIRALARAGMIVPEV
                     RFTRCSLCNTLLRPARRAEILRADYAPGRDHNRTFYWCARCRKLYWHGSHSRDLEKRI
                     QEFFLQGPAGPD"
     gene            complement(12855..13271)
                     /locus_tag="PK679_07705"
     CDS             complement(12855..13271)
                     /locus_tag="PK679_07705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55877.1"
                     /translation="MGSNEDIMHDFVKKELKRLYPSVDGWQIKTAPGTGAGAGFTISR
                     RILGRIEGAYVLVNFDRKVTDKAVKALQELAARSPIPGVRNPRLIIMGPQGAETAGLP
                     PGIEVLSMQSFGYEGKELVWLKRRAQVSEKVPPRSS"
     gene            13452..13931
                     /gene="ruvC"
                     /locus_tag="PK679_07710"
     CDS             13452..13931
                     /gene="ruvC"
                     /locus_tag="PK679_07710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HPC55878.1"
                     /translation="MIVIGIDPGLATIGYGVLSASERIITPMAYSCIKTAPCPGGTPE
                     RLELIYDSVSRLLGEFSPTCMAMETLFFSRNVTSALGVAEVRGVIMLAAQKHGVPVAE
                     YTPNQVKQAITGSGRADKRQMQEMITRLLGLPAIPRPDDVADGLSVALCHIHTARVP"
     gene            13933..14532
                     /gene="ruvA"
                     /locus_tag="PK679_07715"
     CDS             13933..14532
                     /gene="ruvA"
                     /locus_tag="PK679_07715"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: protein motif:HMM:TIGR00084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HPC55879.1"
                     /translation="MIARLRGSIVGCGDGYVILEAGGVGYQVFMPGPLSRQVAEEKGE
                     VILHTHLVVREDGIALYGFLAPAELEMFRMLISVTRVGPALACSILSQMTVSELAAAV
                     IGGDEKALTRLTGVGKKNAGRLILELRDTMRKRADLLAGSSHAVSDDPVRRDAESALL
                     ALGFSSRETRDAVGRAMTGMAEPAVQDVVRAALRIMRER"
     gene            14537..15535
                     /gene="ruvB"
                     /locus_tag="PK679_07720"
     CDS             14537..15535
                     /gene="ruvB"
                     /locus_tag="PK679_07720"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HPC55880.1"
                     /translation="MARRESFTPAQEGEDEVDESVIRPERFSEFVGQDLLKETLRIAI
                     DAAKARGEPLDHTLFSGPPGLGKTTLAHIIAREMGSNLHCTSGPVLEKPGDLAAILTL
                     LKRGDVLFIDEIHRLHTVIEEILYPAMEDFCIDVMIGEGPSARSIKITLEPFTLVGAT
                     TRVGLLGSPFRDRFGLVVRLNLYSTGELAQIVTRSAGIMKIPILPDGALEIAKRSRGT
                     PRIANRLLRRVGDYALVRGDGTVSREVADQALTLLGVDGLGLDEVDRRILHTIVNQFG
                     GGPVGLKTIAIAVGEDSRTIEDVHEPYLIQAGLIKRTPKGREATPAARGHISRQWW"
     gene            15639..>16378
                     /locus_tag="PK679_07725"
     CDS             15639..>16378
                     /locus_tag="PK679_07725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55881.1"
                     /translation="MAGEPGRTGDGGLAMRVAWRGGRPLRGRPVRQPGICILLTVLLV
                     ICLPAGAATVYARDCTIPAPGESGECVIVLDEVSAGLSEFEVTVRIEDPHVGTITSVK
                     FPSFARLNSRSKVPAGSVTLKGADTNNIVRPGDRNVILATLGIRGDAAGTTPIQVTVL
                     GMKDDGGTPYTVPGMNGRLVVLPHNPVSGNGDVTDTAGSLPFSDINGPPGGHSGDLLH
                     PGDAESGPVNTEVPTQTLTPTPTPTMTPT"
BASE COUNT         3188 a         4844 c         5194 g         3152 t
ORIGIN      
        1 aagtccgtca tcacccggaa ctggtcgatc tcttccttgt tcagctgctc gaggaagagc
       61 tctgccgcag agcggacgtc cttgctcgcc gtgatcgccc tccccaccac gacgatgtcg
      121 gcaccggcgg aaagggcatc cctgaccttg tccacgcgta ttccgcccgc tgtggcgacg
      181 agcaaccgcc cgcctgcggc cttgcggagg gcagggatgt caccccaggc atgtgccgag
      241 ccttctgtat cgatggcacg gtggagctca acgacgtcag gctttgcttt gagtcccttg
      301 ataaccctga ccgggtcggc aacgttgagc atgtcgatga ccgagtagat accggtcttg
      361 cgggcctcgg cgatcgcttt ttcgagggtt gcctgcgggg caagacccga gatgacgacg
      421 gcatcggcag aggcatcggc tgccatccgg gcctcgaggt tgccggtatc gaggactttg
      481 aggtcggcga tgatgaaggc agatggccgg accttgcgta tctcgctgat gatggagagg
      541 ccgaacctct tgatcagggg ggtgccggcc tcgatgatga ggtgatcgtt ctgcggaagc
      601 tcggtgagca cggagcggac ctttgccatc tccacgaggt cgagggcgac ctggagatag
      661 ggcgggtccc agaggcgctg gaccttgaag cccatgacgg catggggtgc cctgtccttt
      721 tcgtagagga gggttttttg gtccgggaag ttgtcgagcg cccgggtaat ggcaagtttc
      781 gttgccccgt agttgtaccg gtagatccgg ttgtagtcgg aagcttccgg gtcgaggtag
      841 acgcttgcca ggatgacgag cgactcgagg tccctgtccc cgaaggctcc ttcctcgaca
      901 gcgtccgcaa ctgcctttgc aacggcagcc tgcaccggcc caaacatctc ccggatctgg
      961 cttcccttcc ggagcgttac cttcgggatg atgagggttg ccggttttgt catcaggttg
     1021 ggccggatca cggcaaggag gggtgtatgc cctgcagaga gctgggagag ggcgtttgca
     1081 aacgccgtcc cgaccggtcc gtccttgtcc ccgaggataa ggtccacgtg cgcgagttcc
     1141 ggcccctcgc cgaccagtgc ttcaccgatg tggtacatga gagaatcaga ctccttactc
     1201 agtatggaac cggactgtag ataaatatat gagaattcgg ggatcttttc aggtcaggag
     1261 acgccctgaa acgacgagca ccgcgtttcc ggcgaggatg accctctctc ccttcaccgt
     1321 gaccctgact gcacctcccc tccgggagca ctggaacccc gacaggctcg cctttgaaag
     1381 ccgcccggcc cagtaggggc cgagggaaca atgggcagaa ccggtcaccg ggtcttccgg
     1441 tatcccgatc gagggggcaa agaagcgtga tacgaagtca tagtccggcg tgtccgacgg
     1501 ggcggtcacg atgatccccc tggcaggaag cgcggcgagg gcatccatgt caggatcgag
     1561 ggtgcagacg tccgttgcag aggggagttc aaagaagaga tcgaaccggg tcctccccgg
     1621 gaacaccacg gggcacccga atgcgtcctc gattccctcc ggcggatcgc atgcgtccac
     1681 ggggacggac gggaagtcaa gggctatttc ccgggagtcc atcgaggcag ccagcggtcc
     1741 tgaccgtgtc aggaaacgga tggaggaatt cccctcttcc ctccccgtcg cccagaggac
     1801 aaaagccgag gcaagtgttg catgaccgca caggtcgacc tcggcccggg gtgaaaacca
     1861 ccggagttcc cacgagtcat cgagcctgcg gaggaatgcg gtctccgggt gattcagctc
     1921 aaaagccacg ttctgcatcc aggaactctc cctctcctct ccggtgatgc agactgccgc
     1981 agggttgccg cagaaaggag tgctcgtgaa tgcatcgacg atgtggagtt ctgcgggcat
     2041 gcggaagtgg ttgtgccccg cgggagaaat aatggatcgg cgtacccgga caggaattgt
     2101 acgtcagaaa atgtggggcc ggtgagattt gaactcacga tcgacgggtc tctccgacat
     2161 gcgtcagtgc tccaacggat catcaccagg aatcaggaga cccattgttc atcatccaca
     2221 cgacgcgaaa gaccgctgga gcccgtcgcc attccggact aggccacgac cccttgactg
     2281 tattaactca cattgagcgg atttaagggt tatgctgtga caaggcacga aggaaattcc
     2341 ggtggggcta tatgaatgaa catcgaacga ttttgggatg gatgcaggca gttacgattg
     2401 cggtatttcc gacaagcccc tcctcgggct cacggtaggc gaaatgttct cccaggtcgc
     2461 ccggaaatat ccggataccg aggccctcgt ctcggtgcac caggggatac ggtacaccta
     2521 ccgggacctc ctccggaagg tggaagaact cgggaaggga ctgatggcaa tcggggttga
     2581 aaagggcgac cgggtcggga tatgggccat gaaccatgcc gagtgggtcg tgacccaggt
     2641 cgcgactgca aagatcgggg cgatcatggt caacatcaat cccgcctacc ggacgtacga
     2701 gctcgagtac gtgctccggc aggccgagat ccagacagtg atcctccagg accggttcaa
     2761 gacctccgac tacgtgggca tgttcctcga ggcgtgcccg gaggtcgcgg cgtcccgccc
     2821 gggccacctg cataccgaga agttcccgtt cctgaaaaac gtcatcttca tgggtgaaaa
     2881 cgccccggac ggcatgttct cgtgggacga gatcaaccac atgggacacg acgtatccga
     2941 tgacgaactt tttgcccggg aagaatccct ctcctttgac gatgctgtca acatccagta
     3001 cacgagtggc acgacggggt ttccaaaagg cgtcgtcctc tcccaccaca gcatcgtcaa
     3061 caacggcaac atcatcggcg acgggatgaa cttcaccgaa aaagacaggc tctgcatccc
     3121 cgttcccttc taccactgct tcgggatggt gctctcgaac ctcgcctgca tgacccacgg
     3181 atcgaccatg gtcctgcccg gaccgacgtt caacgcgggg gaagtcctcc agtgcattga
     3241 aaaggagcgg tgcacggccc tccacggcgt cccgacgatg ttcatcgccg agctctccca
     3301 ccccgacttt tcccgttact ccatggagac cctgcgcacc ggtatcatgg caggatcccc
     3361 ctgtcccatc gaggtgatga aggaggtgaa caggaagatg cacatgtcag agatcgtcat
     3421 cgtgtacggg cagacggaga cagcccccgg gatcacgatg acaacgaccc gcgacccgct
     3481 cgagcgcagg gtctcgacgg tggggcgcgt cttcccccat accgagatca agatcatcga
     3541 cccgaagaca ggaaggatcg tcccgcgcgg agaggttggc gagatctgtg cccgcgggta
     3601 ctgcgtcatg aagtgctact acaacaaccc gagtgccacc cacgcaacgc tcgatgcaga
     3661 ccggtggaac cacaccgggg acctcgggac gatggatgcg gaggggtacg tcaagatcgt
     3721 cgggcggtta aaggacatgg tcatccgggg cggcgagaac atctaccccc gcgagatcga
     3781 ggagttcctc cacaaccacc cgaaaattgc cgacgtgtac gtgatcggcg tccccgacga
     3841 aaagtacggg gaggaactga tggcctgggt catggtcgag aagggagaga cgatgaccgg
     3901 ggaggaagtc agggagttct gcaggggaaa gattgcccac tacaagatcc cgcggtacgt
     3961 caagttcgtg acagagttcc cgatgaacat atcggggaag atccagaagt acaagatgcg
     4021 ggagatctcc atcagggaac ttggtcttga gaacgtgtcg aagatcgaga ccgcgtgagt
     4081 ggcagagtgc ggatatcctg ggccgggaag gctgataaaa aggagatgtg aaaagaccgt
     4141 cgtatcgggt accgggagga aacaaggggc ggccctaaga ttcccgcacc ctttccacca
     4201 gtgcccgtgc ggcccgggcc gcttcgcgga ggatctcctc cccgccggga acagtcctgt
     4261 cgtgcatgag gacgctacca tggcagatcg ttgtcatgac ggcgcttccc gggcaggaat
     4321 agacgacgtt cgaggtgacg ctgtgtgccg gcgtgttgca gacggcccgc gagtcgagca
     4381 ggatgatatc agctggctcg cccggtgcga tccttccgtt tccaaacccc agggcccgtg
     4441 cccctgccga tgtcgccatg gcgagggcct cttccgcggg aagcagggtc ggcgagttcc
     4501 atgcaaactt ctggagcagg gcggcaaact tcaggtcggt caacagatcg aggctgttgt
     4561 tcgaggcaca gccgtctgtc ccgagggtga cagacgcccc ggcctctttt aaccagtggt
     4621 agggcatcgc ccgcccggtt gccagcttca tgttgctcac ggggttatgc gaaacgtgga
     4681 cgccccgtcg ggcaaggagc gtgcactcgt cgcggtcaag ccagcagcag tgggctgcga
     4741 tcgtccgggg tgtgagtatc ccgcactcgt cgaggatggc cggggggcgt tttccccact
     4801 gtgcgaccgc atccgtcacc tccttttccg tttcgctcaa gtggatgtgg attccgatac
     4861 cctcgctttc ggagtattcc gcgcaccagg aaagaccttc cttcgagacc gtgtagacgg
     4921 catgggggcc cacggcggcc ttgatccggg ggtttttaag ccccctgacg aacctgacga
     4981 attcttctgt attcctgcac tccgcttccc gtttctcccc ggagaagaga tcgatgaagc
     5041 cgtacgagag gacggcacag aggcccgcct cggcgacggc ccgtgccgcg tcctgcatga
     5101 agaagtacat gtccgagaat gcaaccgttc cggaacggat catctccagg catgcaagct
     5161 tcgtccccca gtagacgtcc tcccccgtca ggtgcgcctc gatcggccag atctttcctg
     5221 acaaccactc ctggagcggc atgtcctcgg cgtatccccg gaagagcgtc atggcagcat
     5281 gggtatgggt gttcacgagg ccgggcaggg cggtcgcccc gttcccctcg atcacgcggt
     5341 cggcccccct gccttccgtg cggccgacgt cgcttcccac cgctgctatg atgccctgct
     5401 cgtcggcgaa gatatcgacc cgctctccat tgagcctcac gtccctgatg aggaggcttc
     5461 ccctgccgga tagatctgtt tccatgtgat ggtctctcct atgacagtcc ccggatgata
     5521 cgcgagagga tctcctcgtt cctcttcgca aacgctgccg acgactcgag gagtccctcg
     5581 tacgtgaacg tctcgtcgga caggccgttt gcatagttgt ctacggtgca gaacgcggcg
     5641 acctccatcc cgagttcagt ggcaagcgtt gcctcggacg caaccgtcat ccccacgata
     5701 tccccgacag acgcgagcgc ccggacttcc gccatggtct ctatacgggg accgggtgtc
     5761 tggacgtacg tcccgccgaa ccgggccccg ggcacgatgg cccgcaggct ttcgaggagc
     5821 cgcggcgaga aaccgggcgt gacatggcat atggcatggt catggatgga cgggaccgga
     5881 gcaaacgaga agtaatcggt cgggatcatg agggtccccg gctgaatctc cttcttcagc
     5941 gagccggacg acccgatcag cacgaggcgg tccacgccca gcagggcgag tgccgcgagg
     6001 tgagcgcggt aattgatcct gtggggagga agcgacctct ggtgccgcag caggatcgca
     6061 atgtcgcctg tcctcacctc gcagttccca aagggggtat gcacgacccg ttcctcaagg
     6121 ggcgggattt gtgcatagag gaggctcgtt cccccgatga tcccgagcat tcaggagccc
     6181 tccagggttt cagagacggt catgggttgt atacatggtt tggggaaagg caatgttctc
     6241 gttttcggta ggaaatctcc catacctgta tcatcaggga ctgcctcacc cttgtaccat
     6301 gggtcggttt gccatcgttg atgatgaccg gatacgggca ggggaatgca cggatatcta
     6361 ttttgagagg gcggtcgcgg tcctcgaaaa gtccgggcat tcgccggatg ttgccatgga
     6421 ggtcacagca tcggatctcc cgggaggatg gggtatcgtg tgcgggactg aggatgtcgt
     6481 ctcgctctgc gagggccttc cgctctcgct cgacgcgatg ccggaaggct ccctcttctt
     6541 tccccgcgaa ccggtgctgc gcgtcagggg gaaatggccg gatatcgcac ggtacgagac
     6601 tgccatcctc gggttcctct gccatgcgtc cggcattgcg acggccgctg ccagggtgcg
     6661 tgcccttgca ggtgaccggc aggtcttctc gtttggttcc cgccgccagc acccggcaat
     6721 tgccacgatg gtcgagcggt ctgcatggat cgggggtgtg gacggcgtga gcaacacctg
     6781 cgccccgccc ggcgttccgc tcgcgggcac gatgccgcat gctttcgtga tgtgctaccc
     6841 ctcgccggaa gaagccttcc gggcattcga ccggcatgcg ccaccggagg tcccccggat
     6901 catgctctgc gatacgtact gcgacgagaa acaggagtcc ctgctcgcgg cgcggtgcgg
     6961 ggcgaggggg gtacggctcg atacgccccg ttcccgccgg ggcgacatgc gggcgatact
     7021 cgaggaggtc aggtgggaac tggatgccgc cgggtacagc gacgtgatgg tcttcctctc
     7081 cgggggaatc acgcccggag atgttgcaca gttccgggac atcgcggatg cgttcgggat
     7141 tggcggtgcc attgcaaacg cgccggtcct cgacttctcg atggacatcg tcgagaagga
     7201 cggtaccggg tgtgccaaga ggggaaagcg gagcggggcg aagcaggtct gggagttgcc
     7261 cgacatgcgc cacgtggtgc tgccggaagg acgaaaggga ccacaaggag cggatccgct
     7321 cctcgtcccg atggtccggg acggggaggt agtgttccgg cagggcatgg agtatgcgag
     7381 ggcccgcgtc ctccggcgca tccctgccat caaagagctc gtggagcggg aaaaccggaa
     7441 agagaggtga gaggagggaa ccgccacgca ttttccccac gggcgggcat tttcccgcat
     7501 cacgacaccc cgtccccgca ggggatcgac gggggagggg agcgacgttc cgcctggcaa
     7561 cacctcctct ccgccggaag gaaacaattc ttttttaggc agtacagcat acattgtagg
     7621 gcacgggccg atagatcagc ggaagatcgc ttccttggca tggaagaggc cgcgggttca
     7681 attcccgctc ggtccatcac tttttgtgtc cggtgcacaa accggagtgt ttttttcctc
     7741 gctcgaagat tcccaatgtg atctgccttg gcaattaagg aatggctcat cccgcaggac
     7801 gaggtttttt tcactctctt cgagaggctt gccgctgtcg tcgtgcttgc ctcctaccgc
     7861 atcgtcgacc ttgtcgatga ctatacaaac gtcagggaga aggttcacca gatcgagcag
     7921 ctggaacacg agggcgacaa gatcacccac gagatctacg aacagctcaa ccagaccttc
     7981 atcaccccgc tcgaaccgga agagatctcg cgcctggcct cggccctcga cgatatcctc
     8041 gactacatca agagcacggc aacgcggatg taccattacc gtatccagga gaccgacccg
     8101 cacatgctcg agctcgcaaa actcatccag ctctctgtcg tcgagctcga ggaggccgtc
     8161 aagggaatcc gcaccatgaa gaacccgcgc cagatagagc agcggtgcat cgaggtgaac
     8221 cgcctggaga acctggcgga cgacgccctc catgccgcgt acgacgatct cttccggaca
     8281 gacgatgcca tcaccatcat caagaggaag gatatctacg agtacctgga ggacgcaacc
     8341 gacaggtgcg aggatgtggc caacgtcctc tcggacattg ccatccgcca ttcctgacgg
     8401 gtcaccatgg agacactgct tgccatcggg atattccttg cactcctctt caattttgta
     8461 aacggcttaa acgatgccgc aaattccatt gccaccgtcg ttgcgacgcg ggtcctgtct
     8521 cccgtcaggg cggtggcgat ggccgcattc ttcaacatgg ccggcccgtt cgtcttcacg
     8581 accgttgtag ccaaaacgat tggaaagggt atcgtcgatc ccggttttct cattcccgaa
     8641 gtgatcgtta tcgggctggg ttcggcagtc ctgtgggtct ttctctcatc ctatgccggc
     8701 attcccatct ctgcgagcca cgcgctcgtc gggggactca tcggttctgc acttgcatgg
     8761 ggagggatcg ggtcggtcct ctggccgtcc atggaactct tcgaaaagac actggccgtt
     8821 ttcatcgcag gcggcgtcac cggggccctc ctcctgtcgt atgccgcgcg gaggaagcat
     8881 gaagaacact gggtcgagta taccgggtta gggttcctgt gcggggcatc cctcctcctg
     8941 cctcctgcca tcgtatccgg ggtgctcccc ctcaagggca tccttgcgat tatcgtcttc
     9001 atcgtggtct cgcctgtcct tggcctcgtg tctgcatacc tcctcgggat ggtggtcatc
     9061 cgcctcttcc gcaactcccc ggcagggaag atgaatgcac tgttttcgag gctgcaggtt
     9121 ttttcagcag cgttttacag cctcggccac ggcagcaacg atgcccagaa cgcgatgggt
     9181 gtcatcacgg ccctcctctt tgcagccggt atcctgaccg agttcgtggt ccctccatgg
     9241 gtcatcatcg tctcggggct tgccattgcg ctcgggacgt tccttggcgg gtggcgggtc
     9301 gtcgagacca tggggaggaa gatcacgaag ctccgtccct accagggttt ctgtgcagag
     9361 acgggaggag gcgtcgtgct ctccttcgtg acggcctttg gcgttccggt ctcgaccacg
     9421 catgccatca gcggctcgat catgggcatc ggggcgacga ggggctactc ggctgtccag
     9481 tggggtatcg tgaggaagat cgtaacggcc tggatactga cgatcccgct cacggcaacg
     9541 tgtggttata tcgcgttcct ggtcttcagg gtggtttttt ccttctgacc ggctccccct
     9601 cggaaggatt gtccgcggac gggcagaggc tcccaagcgg gcaggtcgtg cacgagggtt
     9661 tccgggcggt gcaggttgtc cgcccgtgcc tgatgaggag gtaattgagg tttccccatg
     9721 cactttgtgg gaagagggcc atgaggtcgc gctcgatccg ggcggggtct ttgccggatg
     9781 agaacccgag gcggcgggaa agccgggcca cgtgggtgtc gacggcgacg ccatcgtgaa
     9841 tgccaaaggc atggtcaagc acgatgtttg ccgtcttcct gcccaccccc gggagggtga
     9901 ggaggtcgtc catccgatcc gggacgcgcc cgccgaaccg ctcgatcagc gccctggacg
     9961 tttttatgat gttttgggcc ttctcgcggt agaaacccag agggtggata atatcttcca
    10021 cgtcccgggg atcggcattc gcaaggtctt tgggctccgg gtaccgggaa aagagccgat
    10081 cccggatcgc gttgacgctc ctgtcggtcg tcctggccga gaggatggtc aggatgagga
    10141 tctggaacgg gttctcgaac cggagaaacg ttcgcgggga gccgggatcg ccgtacaggt
    10201 cttcgagaac ggagtatacc cggccggcgc gttccctgtc catcaatggg gtagggcaga
    10261 ttcgaactgc cgtcaaagcg tcccaaacgc tctaggatgg accaggctac cctactaccc
    10321 cgggagatca gatttctgtt gcataccggc aaataggtta tggtgagggt gcccgcaaca
    10381 ggggcacagg ctcctttccg ggagcgcaca cgagcgttcc tgcccttttc ctcccggcaa
    10441 ggacgtcttc gagaagaccg ggctctctcc cgtccaggac gagcagcggt atcccgctcc
    10501 tgctgattac ttttgcggca acgatgtcaa gaacggtgtt tgaccctgcc tcgagcccgc
    10561 cactcccgac gatatcgagc agctctccaa acgtcatccg gtcgaagcgg cgggccgagg
    10621 gatcggcctt cgggtcccgg gtgtaaatgc cgtccacgga cgtcaggttg acgaggatat
    10681 cggcccggga gagttccgcg aggacggcgg cgacggcatc cgtcgtctgc gcgggtgtca
    10741 ccccgcccat gacgacgatc ttcttccttc ccatgtacgc aaccgcctct ccgggtgtct
    10801 gtgcgacctt ccggtatgcc gaatcgccga gcgccgcgag caggagcgtg gcgttgagcc
    10861 gggtgacgag gatgccgatc tcgtcgcagg atgcctcgtc tgcgccgcat tcccgtgcaa
    10921 ccccgatgta ccggcgggct tcgccacccc cgccgacgac aaccgcgata tctgcctgcc
    10981 tgcagagccg ctggagaaca ggtgcgtagg agaggagcgt gtgcgcctcg agcgagggaa
    11041 acaggacgga gccacccagt gagaggacga tgcgaaccat gccaatcatt catttctcca
    11101 tatttcacat atacctgttg aaggcgatgg agcattgtcc ggcctgcggg agcagggaga
    11161 tttacccggt tgcggggggt tgcatcggcc agatctaccg gtgcaaggcc tgcgggtacc
    11221 gcgggtcact cgtggtcgag tgcgacggag acgacgaacc gcggcgtgac agcaataacg
    11281 ggtgagcatt cattacattt atcgccatga accggtgaat gtgagactga tccatgaggc
    11341 agatgcacag ggcactccgg tggtcaccgg aaggacagga gggagcggtc aggtgctcgc
    11401 tctgccccca cgggtgcctg atcaagcccg ggaagacggg gatatgcagg gtgagagaga
    11461 accgggaggg agagctctat gccctcacgt atggccgcgt gagcgcagaa gcggtggacc
    11521 cgatcgagaa gaaaccgctg taccatttcc tgccggggac gctctcctat tccctgggaa
    11581 gcgtcgggtg caacttccat tgtgcgcact gccagaactg gcacatctcc atggcggaca
    11641 cggagatgcc gggactccgc gatctgtcgc ccgaagaggg ggtacggcgg gcacggcagg
    11701 caggctgcgc gagcatctcc tggacctaca acgaacccac gatctggcac gaatacaccc
    11761 tcgacatggg gaacctggcc cggaaagagg ggcttgcgac cgtgtacgtg acgaacgggt
    11821 acattacgga agaggcactg cgggaactct ccccgatgct ccgggcctac cgcgtcgata
    11881 tcaaggcgtt ctcggaggat ttttacagga aggtctgcgg ggcccgcctc cagccggtcc
    11941 ttgattcggc cgtccttgcg cgtgaactcg ggatgcacgt cgaggtggtg acactcgtga
    12001 tccccgggca gaacgacagc ccgcaggaga cgggagccct catccggtgg atacgtgata
    12061 acctcggtga ggatacgccc gtccatttca cgcggttcca cccggaccac cggatgcggg
    12121 acaggggggc aacgccggtt gccgtgctcg agcgcatcta ccggcaggcc cgggaggaag
    12181 gtctccggtt cccgtacctg ggaaatgtct ccccccatcc ctgggagagc acgtactgcc
    12241 cgtcctgcgg agccctctgt atcgagaggt atggatattc cgtgtttttc agggaactct
    12301 ccggggagtc atgttcccgg tgcggggagc ggatacccta tgtccgtgcc ggagggtgaa
    12361 gcaacgggac agacccggtt ccttgcggac cggatgctcg ggacgctgtg ccggtacctc
    12421 cggttcatgg gctacgatac ggtgtctgcg acagagatgg cagaggggaa cagccgggag
    12481 gacactgtcc tcctctcccg tgcccggacc gagggacgga tcctcctcac catggaccgg
    12541 gaactcgccc ggcggggggg tagcgatgcg gttctgatcg aggagaagaa cgtcatggac
    12601 cagatcaggg ccctcgcccg ggcgggcatg attgtcccgg aagtcaggtt cacccgctgt
    12661 tccctctgca atactctgct gcgtccggca cgccgggccg agatcctgcg tgcggactat
    12721 gcccccggga gggatcacaa caggacattc tactggtgtg cgcggtgccg caagctctac
    12781 tggcacggct cgcacagcag ggacctggaa aaaagaatac aggaattctt cctgcagggt
    12841 ccggcaggac cggactagga actcctcggc gggacttttt cgctcacctg ggcacggcgc
    12901 ttcagccaga cgagttcttt gccctcgtac ccgaaactct gcatggaaag cacctcgatg
    12961 ccggggggaa ggcctgcagt ctctgctccc tgcgggccca tgatgatgag gcgggggttc
    13021 ctgactccgg gaatgggaga ccgggcagca agttcctgga gggctttgac tgccttatcg
    13081 gtcactttcc tgtcgaagtt cacgagcacg tatgcacctt cgatgcgacc caggatcctc
    13141 cgggatatgg tgaaacctgc acctgcaccc gtccctggtg cagtcttgat ctgccagccg
    13201 tcaacgcttg ggtaaagccg cttgagctct ttttttacaa aatcatgcat gatgtcttcg
    13261 tttgatccca tggcgaatca cagccgatga tagatagaca ctggtatggt aaaactgttt
    13321 tgtcctgttc ccgctcccgg aaaggcagga atggagaggc gccctctttc acaccgcgat
    13381 agaaaggtat ttgtgggcaa ttacccgata gaatgattga aaaaccagga taactgtcct
    13441 tttcgacctg catgatcgtg attggaatcg acccgggcct tgccaccatc ggatatggtg
    13501 tgctttcggc cagcgagaga atcatcactc ccatggcata ttcctgcatc aagacagccc
    13561 cgtgcccggg ggggacaccg gagaggctcg aactcatcta cgacagcgtg agccgtcttt
    13621 tgggggagtt ttctcccacc tgcatggcga tggagaccct ctttttctcc cgcaatgtca
    13681 cgtcggcgct tggcgtcgcg gaggtgaggg gggttatcat gctggcagca caaaaacacg
    13741 gtgttccggt cgccgagtac actccgaacc aggtcaagca ggcgataacg ggttcgggca
    13801 gggcggataa gaggcagatg caggagatga tcacacggct gctcggcctc cccgcgatac
    13861 cccgtccgga cgacgttgcc gacgggctct ccgttgcact ctgccacatt cacactgcga
    13921 gggtcccctg acatgatcgc gaggctccgg ggcagcatag tgggatgcgg ggatgggtat
    13981 gtcatcctcg aggcaggggg agtcgggtac caggtgttca tgcccgggcc tctttcaagg
    14041 caggttgcag aggagaaggg ggaagtcatc ctgcataccc atctcgtcgt cagggaggat
    14101 ggaatcgcac tgtacgggtt cctcgccccc gcagagctcg agatgttccg catgctgatc
    14161 tctgtgacac gcgtcgggcc tgcgcttgca tgctccatcc tgtcgcagat gactgtctcg
    14221 gaacttgccg cagccgtcat cggaggcgac gaaaaggcac tcacacgcct cacgggagtg
    14281 gggaagaaga atgccgggag gctcatcctc gaactgcgcg acaccatgag gaagagggcg
    14341 gacctgcttg caggcagcag tcatgccgtc tccgacgacc ctgtccggag ggacgcggag
    14401 agcgcgctcc ttgcgctcgg tttctcgtca cgggagacga gggacgcggt gggccgtgcg
    14461 atgacgggca tggccgaacc ggccgtgcag gacgtcgtgc gggcagcact ccggatcatg
    14521 cgggaacggt gatgcaatgg cccggcgtga gtcattcacc cccgcacagg aaggggaaga
    14581 cgaggtcgac gagtcggtta tccgccccga acgcttttcc gagttcgtgg ggcaggatct
    14641 cctcaaggag accctcagga tagcgatcga tgccgcgaag gcgaggggag aaccgcttga
    14701 ccatacgctc ttttcaggcc cgccggggct cggcaagacg actcttgcgc acatcattgc
    14761 ccgcgagatg ggatcgaacc tccactgcac gagcggcccg gtccttgaaa aacccggtga
    14821 ccttgcggcc atcctcacgc tcctcaagag gggcgacgtc cttttcatcg acgagataca
    14881 caggctccac acggtcatcg aggagatcct ctaccccgcc atggaggatt tctgcatcga
    14941 cgtgatgatc ggcgagggac caagtgccag gtccatcaag atcacgctcg aaccgttcac
    15001 gctcgtgggg gcaaccacga gggtcgggct cctcggctca ccgttccggg acaggttcgg
    15061 tctcgtggtc aggttaaacc tctacagcac cggggaactg gcacagatcg tcacgcggag
    15121 cgcagggatc atgaagatac cgatcctgcc tgacggggcg ctcgagatag cgaagaggag
    15181 ccgcggcact ccccggatcg cgaacaggct cctgcggagg gtcggggact acgcccttgt
    15241 ccggggtgac ggtacggttt cccgcgaggt tgcggaccag gctctcactc tccttggtgt
    15301 cgacgggctc ggactcgacg aggtggacag gcggatcctg cataccatcg tcaaccagtt
    15361 cggcggcggg ccggtgggct taaagacgat tgccatcgcc gtcggtgagg acagtcgcac
    15421 gatcgaggac gttcacgagc cgtacctcat ccaggcaggt ctcatcaagc gaactcccaa
    15481 gggaagggag gccactccgg cggcaagggg ccatatttca cggcagtggt ggtaatccgg
    15541 ggaggtaaat tcgccctttt ggggatctaa tataaatacc tggagagatt atcggaaaat
    15601 ataccattat cctgccgaac cggaggggag tctccccgat ggcgggggag ccggggagga
    15661 caggggatgg gggattggca atgcgcgtgg catggagggg tgggcgtcct ttacgaggac
    15721 gtcctgtacg acaaccgggt atttgtatcc tgctcaccgt tctgctggtc atctgcctgc
    15781 cagcgggagc agcaacggtc tatgcaaggg actgcacgat ccctgcaccc ggggagtcgg
    15841 gggaatgcgt catcgtgctg gacgaggtct ctgcaggact ctcggagttc gaagtcacgg
    15901 tcaggatcga ggacccgcac gttggaacca tcacttcggt gaagtttcct tcttttgccc
    15961 ggctcaacag ccggagcaag gttcctgcag gttccgtgac gctcaagggt gcagatacga
    16021 acaacatcgt ccggccgggt gacaggaacg tcatcctcgc cacgctcggg atccgcgggg
    16081 atgcagccgg aacaacccct atacaggtga ctgtgcttgg gatgaaggac gatggcggaa
    16141 cgccctatac agtacccggc atgaacggga gacttgtcgt tctcccacac aacccggttt
    16201 ccggaaatgg ggatgtgacc gatacggccg ggtctttgcc cttttcggat atcaacggcc
    16261 cccctggagg ccattcggga gatttgttgc accccggtga cgccgagtcc ggtcctgtca
    16321 atacagaggt tccaacgcag accctgaccc caacccccac tccgacaatg acgccgac
//
LOCUS       DAOOJU010000033        15591 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_3649_length_15591_cov_15.461509, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000033 DAOOJU010000000
VERSION     DAOOJU010000033.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 15591)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15591)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15591
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3649_length_15591_cov_15.461509"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(95..634)
                     /locus_tag="PK679_07730"
     CDS             complement(95..634)
                     /locus_tag="PK679_07730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011450100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HPC55882.1"
                     /translation="MTAYALEFESIGKRLCQERLVSANFGNMSVRRDEGFLITRTGSF
                     LDNPGEPVFVPLEGDVPREASSEFRLHREVYRRTAHDAVVHAHPVHAVALSLGRDHVI
                     TLDSEGQMFAPKIPVVGGAPGSMEMADNVAGALAVGNLVIVRGHGTFAAGKTLEEAYI
                     LTSLAEHSCRVIILSERAG"
     gene            complement(666..1316)
                     /gene="npdG"
                     /locus_tag="PK679_07735"
     CDS             complement(666..1316)
                     /gene="npdG"
                     /locus_tag="PK679_07735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent F420 reductase"
                     /protein_id="HPC55883.1"
                     /translation="MRVGIVGGTGDIGEGLAMRLSSRHDVVIGSRDEARAVTSSQCCL
                     TTLRQRGLPCSCEGTTNQQAVDRSDIVILAVPFSHVAGTVSGLRGLSGKIVVSPVNPI
                     EKRDYFMYVPPPEGSAAMMIRKLLPAGARLCTAFNTVAANKWRALDQELHLAVPVCGD
                     DRDAKATVMELVNSIEGIRAYDAGPLAASCMVESLTPLLLNIARFNRMRDVGIEFR"
     gene            complement(1319..1591)
                     /gene="trxA"
                     /locus_tag="PK679_07740"
     CDS             complement(1319..1591)
                     /gene="trxA"
                     /locus_tag="PK679_07740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HPC55884.1"
                     /translation="MSRPVLIDFFAEWCGPCKRQGPILEELKRRMGEKIEIRKIDVDQ
                     HMDMANRYGIRVVPTLIIEKDGKIVRSLEGVTSAETLESMLAPLVE"
     gene            complement(1648..3102)
                     /locus_tag="PK679_07745"
     CDS             complement(1648..3102)
                     /locus_tag="PK679_07745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071806 - protein transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecD"
                     /protein_id="HPC55885.1"
                     /translation="MSMEKIKAIVSHWQVALMLILVVLAAIAIAPRFEGGKFTTNLQY
                     GLDLQEGTWLQMEFKAVVAGFETDKDPGDFAKAIQDQTDAEVYVLDKNKIEIRKYIPR
                     EDLETVFNTAGGRLTSYEQGVSKQTAEDVKRILENKLNALGTKDARVNPLVGLSGVSH
                     YIRVELAGVSMAQAKEIVGRQGKFEIRIHTTGNETENVLYGDSITTVGVPSHDSPGSP
                     VWGVSFTLNQDGAEKLQKAAIRTGAVSKPDAHYLDMLLDGKVVYSAPLSPDLAAKLAQ
                     EPIRQLYASTGTGDAGLRDAKNLEIHLRAGALPVDVVVAGSGFVPAELSDYFKLMCVV
                     AFIAAAIAVGIVIFLRYREPAIVLPMMATNLTEIVILLGIATFIQQLDLASIAALIAV
                     LGTGIDQLVIITDEILHEGKVPSPTLYTKRLSRALGIILVSAATVIIAMVPLALMDLS
                     SLRGFAIITMIGVIIGVAVTRPAYGEIIKEILSK"
     gene            complement(3099..3953)
                     /locus_tag="PK679_07750"
     CDS             complement(3099..3953)
                     /locus_tag="PK679_07750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HPC55886.1"
                     /translation="MGFVGYNVNRYTPRQMMVVPAVILLLSLALLGFNMASFGMPVRP
                     GIDFSGGTAVTLFTPDSAEQIRAAFSAYPLLSVGEGVNNGKYLKFGPMDDASLQALAT
                     DIGVRYPDAKIDQIGASFGETLQQQALIALIISFVGMTIVVFIAFRSFVPAGAVVLSA
                     FADIAMTAAGMSLVGIELSLATVAGLLMLIGYSVDSDILLTMRVLKRQGKLEEKLAGA
                     FRTGIIMTTTTIVAITAMWVVALVGQITVVWEIATVLLIGLIVDMMNTWLTNAGIIKW
                     YVQKRGGK"
     gene            4146..4454
                     /locus_tag="PK679_07755"
     CDS             4146..4454
                     /locus_tag="PK679_07755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2551 domain-containing protein"
                     /protein_id="HPC55887.1"
                     /translation="MRSPHEIKAVIESRLKVYLSRDQTGVRRAMLKLFLRMKTLTIAK
                     ICEHLNRRFSISYHSVAAMVGIIASRIGILHVMKNKEGTHSIYQLKEQYVDLVSRIVG
                     "
     gene            4514..4813
                     /locus_tag="PK679_07760"
     CDS             4514..4813
                     /locus_tag="PK679_07760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55888.1"
                     /translation="MYVRSNSRLLPEEIMVNEDVADYIERRGCDFRVCTSCGGPILLP
                     VSMKPPKPTDIQVKIRDRTIFISIHQARYLHSIHRGMLPLFLDPPGDEGPAGNEF"
     gene            4803..5210
                     /locus_tag="PK679_07765"
     CDS             4803..5210
                     /locus_tag="PK679_07765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archease"
                     /protein_id="HPC55889.1"
                     /translation="MSFEELEHTADARFRIRAASLGELYSEAARALMDVMYGRPGEDG
                     QEREIEVDAHDPESLVFAFLSEVLFISEVEGFVVSRADVTVSDTKAKGILHGEPFSPE
                     RHGGGRGVKGISFSDLSLRREDDSYILDVIFDV"
     gene            5217..6650
                     /locus_tag="PK679_07770"
     CDS             5217..6650
                     /locus_tag="PK679_07770"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HPC55890.1"
                     /translation="MLPGIQSLGPCEWEVPLGYVPGMRVPGVFYLSPRLAGTLEEGAV
                     RQLANVATMPGIVKRSLAMPDIHWGYGFPIGGVAAFAFEGGVISPGGVGFDINCGVRL
                     LSTPLEEKDITNRRELAERLYREIPTGVGGKSNLRLSGKDLDSVLVEGASWAVRQGFG
                     RAEDTEFCEERGCMEGADPAAVSEKARARGIPQSGTLGSGNHFLEVQVVREIYDEAAA
                     SAFGLVPGQVCIMIHCGSRGLGHQVCTDHLRVLEAATKRYGISLPDRQLACAPLDSPE
                     GRAYFGAMAASANYAWANRQVIMHRTRKVMEELYHVPQKEMRLVYDVAHNVAKIEEHL
                     VDGKRLRLCVHRKGATRAFGPGSPGIPASYSRVGQPVIIPGSMGTPSFVLHGTQTAME
                     KTFGSTCHGAGRVMSRTQAKRRITGREIRESLGKAGIVVRAPNDASLADEAPDVYKPS
                     AEVVRVVHEVGLSRLVARLEPLAVIKG"
     gene            6647..7222
                     /locus_tag="PK679_07775"
     CDS             6647..7222
                     /locus_tag="PK679_07775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55891.1"
                     /translation="MTPRVGLLWDEKLVFSRYLEECGVSCDHVTPQLLAAPFFRGRFC
                     ALVVPTGFANPAYSRLLPALRASSSRIRKFIGNGGRLLVFGPGIDRADAYDWLPFRVL
                     YTHKKGEGGVECVSSHGCASLFAGFDPATIECDGFFPEHDCEVVARNAQGAVLLRCSA
                     GSGEAVVTTIHEYPSKEFIRQFCSGGSETLL"
     gene            7256..7678
                     /locus_tag="PK679_07780"
     CDS             7256..7678
                     /locus_tag="PK679_07780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2111 domain-containing protein"
                     /protein_id="HPC55892.1"
                     /translation="MNRYVISVDSGPEDLEPVGLALHELLNRLPITVRSARRPGIRIE
                     NGFVVDRNYTGPVLEDVIRENRLIKTTPKTGAYRGVPVIVAPVRDSAGDVLAAIGVVD
                     ITGIFDLATLMEHQSEILRQVCGKDPCPLPSEQAASKR"
     gene            7683..8666
                     /locus_tag="PK679_07785"
     CDS             7683..8666
                     /locus_tag="PK679_07785"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HPC55893.1"
                     /translation="MYEAAFRVLEVLENSDGPVPGEKISAALGISRSAVWKHIKELIN
                     MGYDIQASHREGYRLKKSSNRLLPYEVHKKLRTNVMGRMMRYFESTVSTNWVAKQMVR
                     EEDPAALHGTVIIAEQQTGGMGRLGRSWVSPRGGIWVTIILRPAIPIDRIFMITMAGS
                     IAVARALRKEYDLGALIKWPNDVYIGDKKVAGLLLEISAEADRVNYALLGMGIDVNVS
                     LQDLSVVPNAVTSVSLEVGHDVDRPALLARILKEFESRYSLLEAGEFDSVIREWKSLS
                     CTLERRVRINTLKSSFEGEAIDIDEFGALLVRKDSGKIERVIAGDCIQRQD"
     gene            8699..9244
                     /locus_tag="PK679_07790"
     CDS             8699..9244
                     /locus_tag="PK679_07790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HPC55894.1"
                     /translation="MLSGRERALFIAHTGTFAALLAAGSWISVPFVPVPLTLQTLFLF
                     LAAGFMGRYAVVPVLLFLLLGALNFPVFHNGAAGIGVLLGPTGGYLLGFVPAAFVSGM
                     CYEHRSWQARWAGMGAGASIYYSCGIAWLAYSSGLSLPAAILVGAVPFVPGDLLKAFA
                     AYTVTNRVSRITGVNTRRGGQ"
     gene            9244..9942
                     /locus_tag="PK679_07795"
     CDS             9244..9942
                     /locus_tag="PK679_07795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HPC55895.1"
                     /translation="MIRVEGLSHGILSVPILSIPNGLCVVTGRNGSGKTTLLRLLAGI
                     SVPERGSITVDGRDPATLERGFVHEFPGKNSLFSIVSQEVASPLWFRHALCEEVERAV
                     SRAARSVGIEGLLSREVRNLSGGEQVLCALATAVVGNPALLVLDEWDSHLDSDTAVHA
                     EACIRAMQIPHVVWCTQDMDIAASADYVVFMEGGRVRYSGTPLSVFPALKDTCWYPPS
                     WRWREWSSSSTVSS"
     gene            9897..10610
                     /locus_tag="PK679_07800"
     CDS             9897..10610
                     /locus_tag="PK679_07800"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HPC55896.1"
                     /translation="MEVEGVELVLDRVLVKRGEVSIRASCAFSPGVHLVTGSVGAGKS
                     TLALVAAGLLPPTEGSVERRGIARSMLLFQFPELHLTEKTIREEISSFGVPVDGVLSR
                     SGLFGRGEEDPLSLSRGELKRLLLSCVLARDDDLLILDEPFSGLDCTGRLRLCREIGK
                     KRGGIVILCTHERHFLPRVDVIWEFEDHTLACRGRVPEAIASWQGAPAGIKALVAAGQ
                     VPQNVSFEDIGEAACRTRD"
     gene            10592..11245
                     /locus_tag="PK679_07805"
     CDS             10592..11245
                     /locus_tag="PK679_07805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55897.1"
                     /translation="MQDPRLRLLAVVALSAAAFTSVHGAILAFLWWACTLSGPVCLWR
                     SRWPLLVFFPLLTVSLALFVTGGEWASYSLRLAVVLLVATFAFLDQGPGEFLSVCTWL
                     LGRGLGFDCGLAGEIALSALRFLEDEIRKAKWAFSLKGMPIGIAGIVPLSTGLLYSAL
                     RRASDQGDLLVARGYSGGGSVCARFRTPFRDILVTVAALAIAFIAFRPLGEFFILIQ"
     gene            11307..13046
                     /gene="oadA"
                     /locus_tag="PK679_07810"
     CDS             11307..13046
                     /gene="oadA"
                     /locus_tag="PK679_07810"
                     /EC_number="7.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008948 - oxaloacetate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0015081 - sodium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-extruding oxaloacetate decarboxylase
                     subunit alpha"
                     /protein_id="HPC55898.1"
                     /translation="MRISRSGKVSITDTTLRDAHQSLIATRMRTEDMLTLARKIDGIG
                     FFSVEAWGGATFDSSIRYLIEDPWERLRMLKEVLKQTPIQMLLRGQNLVGYRHYPDDV
                     VDRFVDLAHKNGVDIFRVFDALNDIRNMTRAMKRVKETGAHLQGTICYTTSPVHSNEK
                     FAAMAEELHSLECDSICIKDMAGLIMPDAAYDLISRIKEKTDLPVDLHCHCTSGIAPM
                     SYQAAIEAGVDILDTAMSPFAMGTSQPPTESVVAALQGTPRDTGIDLRALRDVRDECM
                     KIREKYAGILDPISERVDSDVLLYQLPGGMISNLVSQLKEQDALDKLNAVFEEIPRVR
                     RDLGYPPLVTPTSQIVGTQAVFNVLLGGERYRNVTNEVRDYVRGLYGKPPGDIPDDIR
                     KLIIGDEPVITVRPADLLEPVYEKMKAQAMAEGLIKKEEDVLTYILYPAIAPSFLKGE
                     RKPEDIPAKKAAAPEIPVMPHAMEVEVDGEVFSVRIISVGGSSVVQASPAQDKIPRGD
                     MPGGIKAHMQGMVLKILTSRGAQVKKGDLLLVLEAMKMENPIHSPVDGRVTDIFVDTG
                     DTVQSGDVLLVVK"
     gene            13043..14521
                     /locus_tag="PK679_07815"
     CDS             13043..14521
                     /locus_tag="PK679_07815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HPC55899.1"
                     /translation="MTYFEKVLVANRGEIAIRVMRACRELDIETVAIYSTADSDALHV
                     KYADEAFLVGEAPPAKSYLNMERIVDIAKKSGAEAIHPGYGFLAENYRFARLCQEEGV
                     VFIGPSWKTIKAMGSKVESKRMMREAGVPVLPGTEGGIDDPDVACEVAERIGYPVIVK
                     ASAGGGGIGMHIVHDEAHLRASIEAGQRIAQSAFGDATVFIEKYLEKPRHIEFQVLAD
                     EHGHIVHLFDRECSIQRRHQKLVEEAPCPIMTPGLRDKMAASAIAVARASDYTNAGTV
                     EFLYADGNYYFMEMNTRLQVEHTVTELITGRDIVKKQIAIAAGEALPFDQEDVTIRGH
                     AIECRINAEDPLNNFAADPGKILRYRSPGGPGIRVDSGIHMGYTIPPTYDSMIAKLCA
                     WGADRREAIARMRRAIYEYIIIGVKTTLPLHHAIMHNAHFVEGDTHTHFLEEDHMAKT
                     LARYVREEESRMQTLAASLRQGKQIAAITGAVNIYLQSQRKK"
     gene            14604..14716
                     /locus_tag="PK679_07820"
     tRNA            join(14604..14641,14681..14716)
                     /locus_tag="PK679_07820"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14638..14640,aa:Met,seq:cat)
BASE COUNT         3159 a         4634 c         4582 g         3216 t
ORIGIN      
        1 ttttcagtga taccttccat gggcatgcaa cgatcctttt atgatgatgt tctgccagcg
       61 atcgaattta tttcctctct tccaaccgcc ccggtcatcc cgctctttcc gaaaggatga
      121 tgacacggca gctgtgctct gcaagggaag tgaggatgta tgcttcctcg agtgtctttc
      181 cggcggcaaa cgtcccatga ccccgtacga tgacaagatt tcccaccgcg agcgcgccgg
      241 caacattatc ggccatctcc atgctccccg gtgccccgcc gacgaccggg attttgggtg
      301 caaacatctg gccctcgctg tcaagcgtga tcacgtggtc cctcccgaga gagagcgcca
      361 ccgcgtggac cgggtgggcg tgcaccaccg cgtcgtgggc agtcctccgg tatacctccc
      421 tgtggagacg gaactcgctt gaggcctcgc gggggacatc gccctcgagg gggacaaaga
      481 ccggttctcc ggggttgtcg aggaaagaac cggtccgggt gatgaggaac ccttcgtccc
      541 ttcggacgct catgttcccg aaatttgccg acacgagccg ttcctggcag agacgctttc
      601 ctatgctctc aaattccagt gcgtaggctg tcatggaatc aacctccggg aaaaccgggg
      661 agtatttacc tgaactctat tcccacgtcc cgcatcctgt tgaaccgggc aatgttgagg
      721 aggagcggtg tcagggactc gaccatgcac gacgctgcaa ggggcccggc atcgtacgcc
      781 ctgataccct cgatgctgtt gaccagttcc atcacggttg cctttgcatc cctgtcatcg
      841 ccgcagaccg ggacggcaag gtgcagttcc tggtccagtg cccgccactt gtttgccgca
      901 actgtgttga acgccgtaca cagccgggcg cccgcgggca gaagcttcct gatcatcatt
      961 gccgcggagc cctccggtgg cgggacgtac atgaagtagt cgcgcttctc gatcgggttt
     1021 acgggggaga ccacgatctt ccccgagaga ccccggaggc ctgataccgt tccggcgacg
     1081 tgggaaaacg gcacggcgag gatgacaatg tctgacctgt caacggcctg ctggttcgtc
     1141 gtaccttcgc aggagcaggg caagcccctc tgccggagag ttgtcaggca gcactggctg
     1201 ctcgtaacag cccgggcctc gtcccgggac ccgatgacga cgtcgtgccg ggaggagagc
     1261 ctcattgcaa gcccctcgcc gatgtccccg gtgccaccca ctatcccgac tcgcatggtc
     1321 attccaccag gggtgccagc atcgattcca gcgtctcggc gctggtgacc ccttcgaggc
     1381 tcctgacgat ctttccgtct ttttcgatga tcagcgtcgg gacaaccctg attccgtacc
     1441 tgtttgccat gtccatgtgc tggtcgacgt cgatcttcct gatctcgatc ttctctccca
     1501 tcctcctctt cagttcctcg aggatcggcc cctgtcgttt acacggaccg caccattcgg
     1561 caaaaaagtc aattaaaacc ggtcggctca tcactattac caagtgtctt agtggaagaa
     1621 aatgaatgat aaagattttc tatggggtta tttggagagg atctccttga ttatctcccc
     1681 ataggcagga cgtgtcacgg ctacgccgat gatgacacct atcatcgtga tgattgcaaa
     1741 cccgcggagg ctcgagagat ccatcagggc aagcgggacc atggcgatga tcacggttgc
     1801 tgcagaaacg aggatgatcc cgagtgcccg gctcaggcgt ttcgtgtaga gcgtgggcga
     1861 cggtaccttg ccctcgtgga ggatctcgtc cgtgatgatg accagctggt caatacccgt
     1921 cccgagcacc gcgataaggg ctgcaatcga tgcgaggtcg agctgctgga tgaatgttgc
     1981 gataccgagc agtatcacga tctcggtaag gttcgttgcc atcatcggca ggacgatagc
     2041 aggctcgcgg taccggagga agatcacgat cccgacggca atcgctgcgg cgatgaaggc
     2101 aaccacgcac atcagcttga agtaatccga gagctctgcc ggtacgaaac cggaaccggc
     2161 aaccacgacg tcgacaggga gagcacctgc acggaggtgt atctcgaggt tcttggcatc
     2221 cctcagtccc gcatcaccgg ttcccgtcga tgcatacagc tggcggatcg gttcctgggc
     2281 aagttttgcc gctaggtccg gcgagagcgg tgcactgtat acgactttcc cgtcaaggag
     2341 catatcgagg tagtgggcat cgggtttcga gaccgctcct gtccggattg ccgccttctg
     2401 cagtttttct gccccgtcct ggttcagcgt gaacgagaca ccccagaccg ggctgccggg
     2461 ggagtcgtgg ctcggcactc ccaccgtcgt gatgctgtca ccgtagagaa cgttttcagt
     2521 ctcgtttccg gtcgtgtgaa tcctgatctc gaacttcccc tgcctgccca cgatctcctt
     2581 tgcctgtgcc atgctcacgc cggcaagttc cacgcgtata taatgcgaga cacccgaaag
     2641 ccccacgagc gggttgaccc gggcatcctt cgtgccgagg gcattgagct tgttctcgag
     2701 tatcctcttg acatcctcgg ccgtctgctt cgagactccc tgctcgtagg aggtgagtcg
     2761 tccccctgcg gtgttgaaaa cggtttcaag gtcttccctt gggatgtact tccttatctc
     2821 gatcttgttc ttgtcaagga cgtacacctc ggcatcggtc tggtcctgga tggccttggc
     2881 aaaatcaccg gggtccttat ccgtctcgaa gccggcaacg actgccttaa attccatctg
     2941 gagccaggtc ccttcctgca ggtcgagccc gtactggagg tttgtcgtga acttcccgcc
     3001 ctcgaatcgc ggtgcaatgg caattgctgc cagcacgacg aggatgagca tgagcgcgac
     3061 ctgccagtgg ctcacgatcg cctttatctt ttccatgctc attttccacc cctcttctgc
     3121 acgtaccact tgatgatccc ggcattcgtg agccacgtgt tcatcatgtc aacgataagc
     3181 ccgatcagga ggacggtcgc aatctcccag acgaccgtta tctgaccgac cagtgcaacg
     3241 acccacatag cagtgattgc cacgattgtc gtggttgtca tgatgattcc cgtcctgaaa
     3301 gcaccggcaa gcttctcctc gagtttcccc tgccgtttaa ggactctcat ggtgagaagg
     3361 atatccgaat cgacagaata ccctatcagc atgagcagcc cggcaacggt cgcaagggag
     3421 agttcgatcc cgacgaggct catcccggcc gccgtcatcg cgatgtccgc gaatgcagaa
     3481 aggacaacgg ctcctgccgg aacgaacgaa cggaatgcaa taaagacgac gatcgtcatt
     3541 cccacgaacg agatgatgag cgcaatcagg gcctgctgct gcagagtttc tccaaaggac
     3601 gccccgatct ggtcaatctt ggcatcaggg tagcgaaccc cgatatctgt tgcaagcgcc
     3661 tggaggctcg catcatccat cggcccgaac ttcaggtact tcccgttgtt cacgccttcc
     3721 ccgacggaga ggaggggata cgcggagaat gcagccctga tctgctcggc tgaatcgggt
     3781 gtaaaaagag tgaccgccgt accccccgag aaatcgattc ccggcctgac cggcatcccg
     3841 aaactggcca tgttaaagcc caggagggcc aggctcagga ggaggataac ggccgggacg
     3901 accatcatct gccggggagt atacctgttc acattgtaac cgacaaatcc catagcccag
     3961 tacttggtga tacatgggta aaattcttcg gggaaccggg ctatccacgg gtatcccctg
     4021 attggttatt ttccccgccc tcgcacatta ttcaccgtaa tcctccctga atcggggttt
     4081 ccggggacac atgaaactgg atcgaaaaga aatgcttata taaaacttgt ggtgagtacc
     4141 acttcatgag atctccgcac gagatcaagg ccgtcatcga gagccgcctg aaggtatacc
     4201 tttcgcgtga ccagaccggg gtccggcgtg cgatgctgaa actcttcctc agaatgaaaa
     4261 ccctgaccat cgcgaagatc tgtgaacacc tcaacaggcg tttctccatc agttaccatt
     4321 ctgttgccgc gatggtgggc atcatcgctt cccggatagg gatcctccat gtcatgaaga
     4381 acaaggaagg aacccatagc atttaccagt taaaagagca gtatgtcgac ctggtctccc
     4441 gcatcgtcgg ctgaaaacct ccgggcatcc cttcacaatt tttttaccct ttccggtcga
     4501 tgtggtgaga atcatgtatg tacgatccaa ttcacgtctt cttcccgaag agatcatggt
     4561 gaacgaggac gtggccgact atatcgagag gagggggtgt gattttcggg tctgcacctc
     4621 gtgtggcggt cccatactcc ttcccgtgag catgaagcca cccaaaccaa ccgatataca
     4681 ggttaagata agggacagga cgatttttat ctccattcac caggcacggt acctgcactc
     4741 catccacagg ggaatgctcc ccctcttcct ggaccctccc ggggacgagg gacctgccgg
     4801 caatgagttt tgaagagctc gaacataccg cggatgcccg gttcaggatc cgggcagcct
     4861 cccttggaga actctattcc gaggcagcaa gggccctgat ggacgtgatg tacgggcggc
     4921 ctggcgaaga cggacaggaa cgggagattg aggtcgatgc ccacgacccg gaatccctgg
     4981 ttttcgcatt cctctccgag gttctcttca tctcggaggt tgaggggttc gtcgtctcac
     5041 gtgccgatgt gaccgtcagt gacacgaagg cgaagggtat actccatggc gagccattct
     5101 ccccggagag gcacgggggc gggcgcgggg tcaagggtat ctctttttcc gatctctccc
     5161 ttcgccggga agatgattca tatatccttg atgtcatctt tgatgtgtga gtgactatgc
     5221 tccccgggat acagagcctc ggaccctgtg aatgggaagt ccccctggga tatgtcccgg
     5281 gaatgcgggt tcccggcgtc ttctacctct ccccccggct tgccggaacg ctcgaggagg
     5341 gtgccgtccg ccagcttgcc aatgtcgcga caatgccagg aattgtgaag cggtcgcttg
     5401 caatgcccga tatccactgg ggatacggct ttcccatcgg cggggttgct gctttcgcgt
     5461 tcgaaggcgg tgtcatctcc ccgggtggtg tcggcttcga tatcaactgc ggggtcaggc
     5521 tcctttccac accgctggaa gaaaaggaca tcaccaaccg cagggagctt gccgaacgac
     5581 tctaccgtga aatcccgacg ggtgtcgggg gaaagagcaa tctccgcctc tcaggaaaag
     5641 accttgactc cgtcctcgtg gagggggctt cctgggccgt caggcagggg ttcgggcggg
     5701 cagaggacac ggagttctgc gaggagaggg ggtgcatgga aggggccgac cctgcagcag
     5761 tctccgagaa agcccgggcg aggggaatcc cccagagcgg gacgcttgga tccgggaacc
     5821 attttctcga agtgcaggtt gtcagggaaa tctacgacga ggcggcagca tccgcctttg
     5881 gcctcgtgcc gggccaggtc tgcatcatga tccactgcgg ttcccggggc ctgggccacc
     5941 aggtctgcac cgaccatctc cgtgtcctcg aagcggctac gaaacggtac ggcatatccc
     6001 tgcctgaccg ccagcttgcc tgcgcccccc tcgactcccc cgaaggccgg gcatacttcg
     6061 gggcgatggc ggcgtccgca aactacgcat gggcaaaccg gcaggtgatc atgcacagga
     6121 cgcggaaagt catggaggaa ctctaccatg tgccccagaa agagatgcgc ctcgtgtacg
     6181 acgttgccca taacgtggca aagatagagg aacacctcgt cgatggcaaa aggctgcggc
     6241 tctgcgttca ccgcaagggg gcaacgaggg ctttcggacc gggatccccg ggtatccccg
     6301 cctcctattc ccgcgtgggc cagcccgtaa tcatccccgg cagcatgggg acaccctcgt
     6361 ttgtcctgca cgggacacag acagcaatgg aaaagacgtt cgggagcacc tgccatggcg
     6421 ccgggagggt catgagcagg acgcaggcca agcgccggat cacaggcagg gagatccgcg
     6481 agagcctcgg gaaggcgggc atcgtcgtgc gggcaccaaa cgacgcttcc ctggcagacg
     6541 aggcccctga cgtttacaag ccgagtgccg aagtcgtccg cgtcgtccac gaggtcggcc
     6601 tctcccgcct cgtcgcccgg cttgaaccgc tggcggtgat caaggggtga caccgcgggt
     6661 cggcctgctc tgggacgaaa aactcgtctt ttcccggtac ctcgaagaat gcggggtctc
     6721 ctgcgaccac gtgacccccc agctcctcgc ggcacccttc ttccggggca ggttctgtgc
     6781 cctcgtcgtc ccgacgggct ttgccaaccc ggcctattcc cggttgctgc ctgcactccg
     6841 ggcatcatcg tcgcgcatca ggaaattcat cgggaacggg gggagactcc tcgttttcgg
     6901 gccgggaatc gaccgggcag atgcctacga ctggctcccg ttccgggtgc tctatacgca
     6961 taaaaaggga gaaggggggg tcgaatgcgt ctcctcccac ggatgtgcat ccctttttgc
     7021 cgggttcgac cctgccacaa tcgagtgcga cgggttcttc ccggaacacg actgcgaggt
     7081 cgttgcacgg aatgcacaag gggcagttct cctccggtgc agtgccggca gcggcgaggc
     7141 ggttgtcacc accatccacg aatacccttc aaaggagttc atccgtcaat tctgctccgg
     7201 cgggtcggaa acattattgt gaacaaagac cagggaatag agtaaggatc tgcccatgaa
     7261 tcgctacgtt atctccgtgg acagcggccc tgaagacctc gaacctgtcg gccttgcact
     7321 ccatgaactc ctcaacaggc tccccatcac tgtccggtct gcccgtcgcc ccggcatcag
     7381 gatagagaac ggcttcgtgg tggacaggaa ttacacgggt cctgtcctcg aagatgtcat
     7441 cagggagaac cggcttatca agaccacccc caagaccggg gcctacaggg gtgtgccggt
     7501 catcgtggca cccgtccgcg attctgccgg agacgttctt gccgcaatcg gtgtcgtgga
     7561 catcacgggg attttcgacc ttgccacgct catggaacac cagtcagaga ttttgaggca
     7621 ggtctgcggc aaggacccct gcccgctccc ttccgaacag gccgcatcca aaaggtaata
     7681 ccatgtacga ggcagcattc cgtgtccttg aggtgctcga aaacagtgac ggcccggtcc
     7741 cgggtgagaa gatcagcgct gccctcggga tatcccggtc ggcggtctgg aagcacatca
     7801 aggaactgat caacatggga tacgatatcc aggcatcgca ccgggaggga taccgcctca
     7861 agaagagcag caaccggctg ctcccctacg aagtccacaa gaagctccgg acgaacgtga
     7921 tgggcaggat gatgcgctac ttcgagagca ctgtctcgac gaactgggtg gcaaagcaga
     7981 tggttcgtga ggaggaccct gctgcactcc acggaactgt catcatcgcg gaacagcaga
     8041 cggggggcat ggggcggctg ggccggtcat gggtttcgcc ccggggtggg atatgggtaa
     8101 cgatcattct caggccggcg atccccatcg acaggatttt catgattacg atggccggat
     8161 cgatcgcggt tgcccgtgcc ctccggaagg aatatgacct tggtgccctg atcaagtggc
     8221 caaacgacgt gtatatcggg gacaagaagg tcgcggggct cctcctcgag atatctgccg
     8281 aggctgacag ggtcaattat gccctgctcg gaatgggtat cgacgtgaac gtctccctcc
     8341 aggacctctc cgtggtcccc aatgccgtca cctccgtgag ccttgaagtc ggccacgatg
     8401 tcgataggcc cgcgcttctt gcccggatcc tgaaggaatt cgagagccgc tattcgctgc
     8461 tcgaggccgg agagttcgac tcggtcatcc gcgaatggaa gagtctctcc tgtacgctgg
     8521 aacgccgggt ccggatcaac accctgaaat cgagtttcga gggtgaggca atcgatatcg
     8581 acgagttcgg tgcgctgctc gtccgcaagg acagcggaaa gatcgagcgc gtgatcgccg
     8641 gggactgtat ccagcgacag gattaactcg tcaaccagga aaaatttcat ggttgacgat
     8701 gttgtccgga cgggagagag ccctctttat cgcccatacc ggcacttttg ccgcgctcct
     8761 cgcagcaggg tcctggatct cggttccgtt cgttcctgta cctctgaccc tccagaccct
     8821 ctttctcttc cttgctgcgg ggttcatggg gaggtacgcg gtcgtaccgg tccttctctt
     8881 cctgctgctc ggtgcactca atttccctgt tttccacaac ggggcagccg ggatcggcgt
     8941 tctcctcggg ccgacgggag ggtacctcct tgggtttgtc ccggcggcgt tcgtctccgg
     9001 tatgtgctat gaacaccgga gctggcaggc ccggtgggca ggtatgggag cgggtgcatc
     9061 catctactat tcatgcggca tcgcgtggct tgcgtattct tccggtctct cccttcctgc
     9121 tgctatcctc gtcggtgcag tgcctttcgt gcccggtgac ctgctcaagg catttgccgc
     9181 gtatactgtt acgaacaggg tttcccggat caccggtgtg aacacccgca gggggggaca
     9241 atgatgatcc gggttgaggg actttcccac ggcatcctct ccgtcccaat actttccatt
     9301 ccaaacggcc tttgtgttgt cacgggcagg aacgggagcg ggaagacgac actgctccgt
     9361 ctccttgcgg gaatcagcgt tcccgaaaga ggatccatca cggttgacgg gagagacccc
     9421 gctaccctgg agaggggctt tgtccacgag tttccgggga aaaacagcct cttctcaatc
     9481 gtttcccagg aggtagcctc gcccctctgg ttccggcatg cactttgcga agaggtggag
     9541 cgagccgtat cacgtgcggc ccggtccgta gggatagagg ggctgctctc ccgcgaggtc
     9601 cggaacctct cgggcgggga acaggtgctc tgtgcgctcg caacggcagt ggtcggaaat
     9661 cccgccctcc tcgtgctcga cgagtgggac tcgcacctcg atagcgatac tgctgtccat
     9721 gcggaggcgt gtatccgggc gatgcagatt ccccacgtgg tctggtgcac gcaggacatg
     9781 gacattgctg catccgccga ttacgtggta ttcatggagg ggggacgcgt caggtattcg
     9841 ggcacaccgc tctctgtctt ccctgcactg aaggatacct gctggtaccc gccctcatgg
     9901 aggtggaggg agtggagctc gtcctcgacc gtgtcctcgt gaagcggggg gaggtatcga
     9961 tccgtgcttc atgtgctttt tctcccggtg tccacctcgt gacgggaagt gttggtgccg
    10021 gcaaatcgac gctggcactc gttgcggcag ggcttctccc gcccacggag gggtccgtgg
    10081 aacggagagg gatcgcccgt tccatgctcc tcttccagtt cccggagttg cacctgacag
    10141 aaaagaccat ccgcgaagaa atatcgtcgt ttggtgttcc cgtagacggt gtgctctccc
    10201 ggtccggtct ctttggccgt ggcgaagaag accccctctc cctctcgcgt ggcgagttga
    10261 agaggctgct tctctcctgc gtccttgcac gggacgatga cctgctcatc ctcgacgagc
    10321 cgttcagcgg cctcgactgc accggcaggc ttcgtctctg cagggaaatc ggaaaaaaga
    10381 gggggggcat cgtcatcctg tgtacccatg agcggcattt cctcccccgc gtggacgtca
    10441 tctgggaatt cgaagaccac acactcgcct gccggggacg ggttcccgaa gcaatcgcat
    10501 catggcaggg ggcccctgca gggattaaag ccctggttgc cgcaggacag gtaccccaaa
    10561 acgtgtcatt cgaggatatc ggggaggcgg catgcaggac ccgcgattga ggctgcttgc
    10621 agtcgttgca ctctctgctg ctgcctttac gtccgtgcat ggcgcaatcc tggctttttt
    10681 gtggtgggcc tgcacgctct ccgggcccgt ctgcctctgg cgttcccggt ggccactcct
    10741 cgtttttttc cccctcctca ccgtatccct cgcccttttc gttacgggtg gagaatgggc
    10801 atcctacagc ctcaggctcg cagttgtcct tctcgtcgcc actttcgcgt tcctggacca
    10861 ggggcccggc gagtttctca gcgtctgcac gtggctcctg gggcggggcc tgggctttga
    10921 ctgcgggctt gccggtgaaa ttgccctttc cgccctcagg ttcctcgagg atgaaatcag
    10981 gaaggcaaag tgggctttct ccctcaaggg gatgccgatc gggatcgcgg gtattgtccc
    11041 cctctccacc ggcctcctgt acagtgccct ccggagggcg tctgaccagg gagacctcct
    11101 cgtagccagg gggtactccg ggggcgggtc ggtgtgtgcc cggttccgga caccgtttcg
    11161 cgatatcctt gtcacggttg cggcattagc cattgcattc atcgcttttc gaccactcgg
    11221 agaatttttt atactaatac aatgaaggat ttagaggttt agctgttgcc tcccgctcga
    11281 gctgccgcca agcccggagg atcccgatgc gtatttcccg ttccggaaag gtttcaatta
    11341 cagataccac gttgagagat gcccatcagt ccctgatagc aacgcgcatg cggacagagg
    11401 acatgctcac cctcgcccgg aagatcgatg gaatcggttt tttttcggtg gaggcctggg
    11461 gtggtgcaac cttcgactcg agcatccgat accttatcga ggacccctgg gagaggctcc
    11521 ggatgctcaa ggaggtgctg aagcagaccc ccatacagat gcttctccgg ggccagaacc
    11581 tcgttggtta ccggcattat cccgacgacg tggtcgaccg cttcgtggat cttgcccata
    11641 aaaacggcgt ggacatcttc cgggtctttg acgccctcaa cgatatccgg aacatgaccc
    11701 gggcgatgaa gcgggtgaag gagacgggag cccacctgca ggggaccatt tgctacacaa
    11761 cgagcccggt ccactcgaac gagaagttcg ccgccatggc agaggaactc cactcactcg
    11821 aatgcgattc catctgcatc aaggacatgg cgggactgat catgccggac gcggcgtatg
    11881 acctgatttc ccggataaag gaaaagacgg acctccccgt ggacctccac tgccactgca
    11941 cgagcgggat tgcaccgatg agttaccagg cagccatcga ggccggtgtc gatatcctcg
    12001 acaccgcgat gtctcccttc gccatgggga cgtcgcagcc cccgaccgag agtgttgtcg
    12061 ccgctctgca gggaacaccc cgcgacacag gaattgacct gcgtgccctg cgggacgtgc
    12121 gggacgagtg catgaagatc cgcgagaagt acgcgggtat cctcgacccg atatccgaga
    12181 gggtcgacag cgacgtactc ctctaccagc tccccggcgg catgatctcg aacctcgtct
    12241 cccagctcaa ggagcaggac gcccttgaca agctcaatgc cgtcttcgag gagatccccc
    12301 gggtgcgcag ggaccttggc tacccgccgc tcgtcacgcc cacgtcccag atcgtgggca
    12361 cgcaggctgt cttcaacgtc cttctcggcg gtgaacgcta caggaacgtg acaaacgagg
    12421 tcagggacta tgtccgcggg ctctacggga aaccccccgg tgacattccc gacgatatcc
    12481 ggaaattgat catcggcgac gaaccggtga tcacggtccg gcccgcagac cttctcgaac
    12541 cggtgtacga gaagatgaaa gcgcaggcaa tggccgaggg gctgataaaa aaggaagaag
    12601 acgtcctgac gtatattctg taccccgcaa tcgctccctc gttcctgaag ggcgagagaa
    12661 aacccgagga tattccggca aagaaggcag ccgctcccga gatccccgtc atgccccatg
    12721 cgatggaagt ggaggtggac ggggaagtct tctcggtccg gatcatatca gtcgggggaa
    12781 gctccgtcgt ccaggcatca ccggctcagg ataagatccc ccgcggagat atgccgggcg
    12841 ggatcaaggc ccacatgcag ggcatggtcc tgaaaatcct caccagtcgc ggcgcccagg
    12901 tgaagaaagg tgacctcctc ctcgtgctgg aggcgatgaa gatggaaaac cccatccaca
    12961 gcccggttga cgggagagtc acggacatct ttgtcgatac cggggacacg gtgcagagcg
    13021 gtgacgtgct cctggtggtg aaatgaccta cttcgagaag gtgctcgtcg caaaccgggg
    13081 cgaaatcgcg atccgcgtga tgcgggcatg ccgggagctc gacatcgaga cggtcgccat
    13141 ctattccacc gcggactccg acgccctcca cgtgaagtac gcggacgagg ctttcctggt
    13201 cggagaagcc ccgccggcaa agagttacct taacatggag aggatcgtcg atatcgcgaa
    13261 gaaatcaggg gccgaggcca ttcatcccgg ttacgggttc ctcgcagaga actaccggtt
    13321 tgcaaggctc tgccaggagg agggggtcgt cttcatcggg ccgtcctgga agacgatcaa
    13381 ggccatgggc tcgaaggtcg agtccaagag gatgatgcgg gaggccggcg tccccgtcct
    13441 tcccggaacg gaagggggca tcgatgaccc tgacgttgcc tgcgaggttg cggaaaggat
    13501 cgggtacccg gtgatcgtga aggcgagtgc cgggggcggc gggatcggga tgcacatcgt
    13561 ccatgacgag gcccatctca gggcgtccat cgaggccggc cagcggattg cccagtcggc
    13621 gttcggcgat gcgacggtct tcatcgagaa gtacctggag aagccccgtc acatcgagtt
    13681 ccaggtgctc gccgatgagc acgggcacat cgtccacctc ttcgaccgcg agtgctccat
    13741 ccagagacgt caccagaagc tggtagagga agccccgtgt cccatcatga cgcccgggct
    13801 ccgcgataag atggcagcct ccgcgattgc agtggcacgg gcatcggatt ataccaacgc
    13861 cgggactgtc gagttcctgt acgccgacgg gaactactac ttcatggaga tgaacacgcg
    13921 cctccaggtc gagcacacgg tcacagaact catcacgggc cgggacatcg tcaaaaagca
    13981 gatcgcgatt gctgcaggag aggctctccc gttcgaccag gaggacgtga cgatccgggg
    14041 ccacgccatc gagtgccgga tcaatgccga ggacccgctc aacaactttg ctgcagaccc
    14101 gggaaagatc ctccggtacc gttccccggg cggtcccggc atacgggtcg attccgggat
    14161 tcacatgggg tataccattc ccccgaccta tgactcgatg atagccaagc tctgcgcctg
    14221 gggagccgac cggagggagg cgatagcccg gatgcggcgg gcaatctacg agtatatcat
    14281 catcggtgtg aaaacgacgc tccccctcca ccatgccatc atgcacaacg cccacttcgt
    14341 cgagggtgac acacacaccc acttcctcga agaggatcac atggcaaaga cgctcgcccg
    14401 gtacgtccgc gaagaggagt cgcggatgca gacgctcgcg gcatccctcc gtcagggcaa
    14461 gcagatcgcg gccataacgg gtgcggtcaa tatctacctc cagagccagc ggaagaagtg
    14521 aggagaaacc ccttttatcc ccttttactc caaaacagaa cctttaagag cgtatactgc
    14581 gtttttaata tgcactcttg tgcgctgcgg tggcctagct ggttagggcg ccagactcat
    14641 agggttttga gcagacacac aagcgcccat catctgagat atctggaggt cgtgggttcg
    14701 gatcccaccc gcagcattcg atcaccaggt tacatgctca aggctcccct ttataggggg
    14761 tggcctgaaa ctctcttttg tatgccttcc acacctgtga cagctgagac gttcggttgt
    14821 atcaaatctg aatatgcgga tgccgctatc aaccgggggc tcacgaccgg acagatcaac
    14881 aacagagacc tgcaacttat cagagaatat cttgccgaaa agcgggcgac cgcaggaata
    14941 aactcccccg ttgcaacaaa accagctgca ccctcatatg ctggcgacat tttatttcac
    15001 ccttccaaga cctcccatag gctcgattta cttcggcatc gaatcgctac ggtcaggcca
    15061 ccgtataagg ggacggccgt gcaaacagaa taccaccgct gatcacgtcg acatcctcag
    15121 agggttcctt ttctcgttga tcgagaacga atatctcgat ctgcctgaga cgaagattcg
    15181 aaggataaaa aagtccgccc agggatacga taaccaagag ggccgccgac ctgctgactc
    15241 caaaagagat catgacgttt ctcggcacct caatagggat caggaaccgg gggtttgtta
    15301 atgaccatgt gcgtaggagg attcagtgtt ggcgaaatcg cttagattat ttgggtagat
    15361 ctcgaaagcg gatccgaagg ggattgccgt caatgtcaag tttaaaacat catatccccg
    15421 caatataggg ctcattatgg caaaggaatt ccccgcggaa tagaaggctg attatcacaa
    15481 tgaagtgacg cttgactcgt ctgtgtttct taacgaacgc ccggggccac tgacgagggc
    15541 gggtgacgat gggggatctg tgatcgctat tatgctcctt ggggaggact g
//
LOCUS       DAOOJU010000034        15535 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_3661_length_15535_cov_14.475323, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000034 DAOOJU010000000
VERSION     DAOOJU010000034.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 15535)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15535)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15535
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3661_length_15535_cov_14.475323"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..325)
                     /locus_tag="PK679_07825"
     CDS             complement(<1..325)
                     /locus_tag="PK679_07825"
                     /inference="COORDINATES: protein motif:HMM:NF025910.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55900.1"
                     /translation="MQKVPWLLAVLVVLVPFLAACVSYPDADLAREGDRLLEQGNLEQ
                     SLVLFDRAIAINGENVEAWEGRGKALHLMGRESEAFESLNRSLALDPSSAPRWVALGD
                     VLLAMD"
     gene            complement(455..1240)
                     /locus_tag="PK679_07830"
     CDS             complement(455..1240)
                     /locus_tag="PK679_07830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55901.1"
                     /translation="MVKKGLFVLLLAFFLLGYASADDPMNATFETQSIHTETSVVVYG
                     TFSNEASIVWQQSSGALDDNTYLSASERQATMSYSESTNANNGYVEYNKVADLDTGNQ
                     VVNQNNFKSVRQLDFVSFNDAYGSVISSESLALDGASMGSPASDRILCPFGASSGDTI
                     PAYCNIVEMGSSFSGTSVSMTTIASERHVAAKADVPVAMDYSISLAGQGTASAYYRMH
                     LQSARGDSLNKSMDIMGSEKTTASGTIQSFEKTMSYGSGVRRY"
     gene            complement(1350..1700)
                     /locus_tag="PK679_07835"
     CDS             complement(1350..1700)
                     /locus_tag="PK679_07835"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55902.1"
                     /translation="MKYIVTGALLLLLLAVSTVSAAYAGDFCNVFEAGSSFSGKSVSM
                     TTIAGDRFVGSGVLKPVTTSYSADISGIGTATSFMRGTMQGASKSVSFSQQTTASGTI
                     MKYFIEYHWSSGRS"
     assembly_gap    1950..2049
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(2204..2986)
                     /locus_tag="PK679_07840"
     CDS             complement(2204..2986)
                     /locus_tag="PK679_07840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55903.1"
                     /translation="MKKFAIAVLALAFLAVGMAMADRPVNQTYETQGVTTSTAVVVSG
                     ALTNAESIVWTMSDQDITGASLDDGEVQYTMAYTQSVQGNNGYAEFNAGSALDTANKV
                     VNTNNYKTTKQLDYVSYNDAYGQVATAESLTLDGAGMNTTTADKFLCPFGASSADFPA
                     FCNIIEVGSTFSGTAVSMTTVADERHVAKSADVPVVVDYSVGLAGQGSASAYYRAHFQ
                     EARGNDSANKSLDIVASEKTTASGVITSFTKAINYQSGVRRY"
     gene            complement(3257..3982)
                     /locus_tag="PK679_07845"
     CDS             complement(3257..3982)
                     /locus_tag="PK679_07845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC55904.1"
                     /translation="MFDSGDRVLLAGRGRTFFVRAGTGSFSTDRGVLDLDALLTASPG
                     DIVRTHTGEEFRVLVPRAPDFFARASRSGAPMLPKDIGLVIACTGMNRNDRVLDAGTG
                     SGIAAIYFGGVAGKVVTYEIRPEFARQAEKNVADAKLSNVQVVCGDVADASGTYDVVH
                     LDLHVSPDIIRHAWSLLVPGGYLACYTPFLEQLFTVMDTASGLFPEVTAHECIGREIA
                     RGPRGTRPSTRVCHTGYVTVARK"
     gene            complement(3975..4319)
                     /locus_tag="PK679_07850"
     CDS             complement(3975..4319)
                     /locus_tag="PK679_07850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nascent polypeptide-associated complex protein"
                     /protein_id="HPC55905.1"
                     /translation="MMPGNINPRKMKQMMKQLGMQVEPIEDVRKIVISTGRGDYVFDS
                     AEVAVMTMQGITTYQITGNPHFEPAAPQIPDEDVRMVAEQAGVSPEAARDALIRTGGD
                     IAAAIIQLSEHV"
     gene            complement(4204..4812)
                     /locus_tag="PK679_07855"
     CDS             complement(4204..4812)
                     /locus_tag="PK679_07855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HPC55906.1"
                     /translation="MSNGSTSSSESSSLARVRVIADYQFGRGAGRGLFPDGCTFVYSR
                     TGRVRQVLDPESGQRLATVRASDGRLTLGIAGARRLMEVIPPPAYRVGILPDVADFAR
                     NGKNVFCRHVVSADPEIRAGDEVMVVTGDDALCATGTAVLSGAEILVFNYGVAVKVRQ
                     GAKTHDAGKHQPEKDEADDETAGDAGRADRGRAENRHLHRQG"
     gene            complement(4748..6145)
                     /locus_tag="PK679_07860"
     CDS             complement(4748..6145)
                     /locus_tag="PK679_07860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HPC55907.1"
                     /translation="MSLRDDAREVARVILSHHEVTVISHIDADGIAGESILAQALSRA
                     EVPHKSVFVRQLEPLTMKQVPEDDSLKVFCDLGAGQQNLLLERGLSREEVVIIDHHVS
                     QPCGRDYLQANSLLSGHVKMSAAGVAYMVAREMDSGNADLSRLAVVGNVGDMMAREDC
                     GLTGPAREIAIEGAEAGWIEIVPRDLNCYGISTRPLHVCLAYNDDPYIPGISNNASGA
                     LRFLQRLGIELQTPEKRWRVWEEFSPDEKRLVTSSLAQQLIACGEPTDRLFCESYLFP
                     GEAERTPLRNAQEFATLLNACGRWTRPRVGGAICRGDRGEAFREAEHMLSNHRAVIRE
                     LLEYILDTGVRELSHIQYIHVGDRYPDTIVGIGAGMALSRLNMDKPILVMVVQPEDTS
                     LTKVSMRTTERVVSRGIDLQQALTIASAEVGGAGGGHRIAAGAYIPRESEDTFVERVN
                     QLIGEQFARPRQGHC"
     gene            6355..7755
                     /locus_tag="PK679_07865"
     CDS             6355..7755
                     /locus_tag="PK679_07865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HPC55908.1"
                     /translation="MVRPECREFMETGIVSPERMRAIDANARALGVSSLQLMEAAGYA
                     LAGFVRSLGRGPILFLCGKGNNGGDGLVAARHLQDEDVTVLFLDGEGRSAECAYQLRS
                     LAHCPVRCIPVRCPGDATAEKRIFEEAGCIVDALLGTGSRGEPREPVRTLAGLASLSP
                     AVKVSADVPTPGFVPDRILAFHRPKVEGSVVASIGIPLAAEITVGPGDLTLVRKKDPS
                     AHKGAGGEVLVVGGGPYQGAPYLAGLGALRAGADIVRIASPVFEPVPDLIYERLEGKV
                     IAGEHLERLRELARTADVVVMGNGLGDRSHHVMVDLAKECPKAVVDADALRRPLPRAA
                     DTIYTPHAGEFRRAFSREPPDDIIGRARAVKKAAGEGTVLLKGRVDIISDGARVRFNR
                     TGSPIMTVGGTGDILAGVAGALFCKLPAFEAACIAAYVNGRAGMAVEEAIGGGMLPTD
                     LLDRIPLELYRKEETE"
     gene            7752..8234
                     /gene="moaC"
                     /locus_tag="PK679_07870"
     CDS             7752..8234
                     /gene="moaC"
                     /locus_tag="PK679_07870"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HPC55909.1"
                     /translation="MREFSHIEDDRARMVDISGKGEVYREAVASGRIVLREETLRAIR
                     EGTVVKGNVLATARVAATLAVKGTPALIPMCHPIPVSSIEVDFHDRGDSIEACVRVRS
                     LGRTGVEMEALTGVSVALLTIWDMVKSAEKDSRGQYPVTCITGIRVLEKRKGEPIGEE
                     "
     gene            8368..8958
                     /locus_tag="PK679_07875"
     CDS             8368..8958
                     /locus_tag="PK679_07875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15e"
                     /protein_id="HPC55910.1"
                     /translation="MARSMYAYVREAWKRPAQTGVDELLWERMQVWRREGSVVRIDRP
                     TRIDRARNLGYKAKQGIVMVRVKVRRGGRRKSRYVRARRSIRMGVNRITPAKSLQRMA
                     EERASRRYPNMEALNSYWVGQDGRYKWYEVIMVDGHHPAIRNDSQLSWMGDAVHRGRA
                     ERGKTSAGRKGRGMGTRGRGTEKTRPSIRSHGNLGK"
     gene            8994..9638
                     /locus_tag="PK679_07880"
     CDS             8994..9638
                     /locus_tag="PK679_07880"
                     /inference="COORDINATES: protein motif:HMM:NF013993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase P subunit p30 family protein"
                     /protein_id="HPC55911.1"
                     /translation="MQCTDACVFPYPGGDSSLRRMALSARELGFDSIVAACPANGTYC
                     GVEVIGMKVMGRTGAGAKEVSHAEPGQEGRAITVAHAGEYAANRALLRTGKIMVLRGI
                     QWTPKNSFDHILSRMAAERGIAVDIDFSSLICERGSSRQRVIQRYADIVRLHRKFGFS
                     LTLSSGARSVLGMRSPREMTVLGGLFGLEEDDTGRALGTVRQLLFPRSPVEVVE"
     gene            9635..10120
                     /locus_tag="PK679_07885"
     CDS             9635..10120
                     /locus_tag="PK679_07885"
                     /inference="COORDINATES: protein motif:HMM:NF014013.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpp14/Pop5 family protein"
                     /protein_id="HPC55912.1"
                     /translation="MKPLPPTLRENRRYVLVRIEPPWFETDSRTLYGALAESVTALFG
                     DTGMARIQPAVISASRGFAIVRCIRSTEDELLAGLAAVHHVGSQKVALRSVRTSGTLR
                     ALRSTIREGRFCPAMETGEARFGGKTYESVSYQLEKVDLFEKGFKSQEPLFLTAEDLE
                     E"
     gene            10123..10848
                     /gene="psmA"
                     /locus_tag="PK679_07890"
     CDS             10123..10848
                     /gene="psmA"
                     /locus_tag="PK679_07890"
                     /EC_number="3.4.25.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000502 - proteasome complex [Evidence
                     IEA];
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaeal proteasome endopeptidase complex
                     subunit alpha"
                     /protein_id="HPC55913.1"
                     /translation="MQPQAYQMGYDRAITVFSPDGRLYQVEYAREAVKRGTTAVGIKC
                     RDGVVLIVDKRVSSRLLEASSIEKIFKIDEHIGVASSGLVGDARALVDRARIECQINR
                     ITYDEKIDVEALAKKLGDHMQTYTQFGGARPYGTALLIAGVSDGECRLFETDPSGTLL
                     EYKATGIGIGRNAVMKVFEEEYDYDTGINESILLGIKALHDATEGKFDVNTVEIGVIE
                     RENPLFRKMSKEEVEAFVEKFEK"
     gene            10862..11557
                     /locus_tag="PK679_07895"
     CDS             10862..11557
                     /locus_tag="PK679_07895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly factor SBDS"
                     /protein_id="HPC55914.1"
                     /translation="MIPLEKAVCARLESHGEKFEILVDPDLAVRFRQGEDVPLEEMVA
                     ALYVFSNASRGTRASEESLEKVFQTTEFSEIAPRIIRKGEIHLTAEQRRQMIADKRRQ
                     VIHFIARNAINPQTGLPHPPQRIEMAMEEARVNIDLYKSLDELVKETVKALRPILPIR
                     FEELRIAVKIPADFAPRAFGEIQSAATIERDEWQKDGSWICIVRIPAGIQGDFYGLVN
                     RISKGQGEVKILD"
     gene            11616..11909
                     /locus_tag="PK679_07900"
     CDS             11616..11909
                     /locus_tag="PK679_07900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L37ae"
                     /protein_id="HPC55915.1"
                     /translation="MSSGQQKAKGRVTGSAGRFGPRYGRFIRKRVTETEKISRAAHRC
                     PRCDTMAVKRVGTGIWACRKCGFKFAGGAYTPQTPALRIALRAIDRTATDISE"
     gene            11917..12051
                     /locus_tag="PK679_07905"
     CDS             11917..12051
                     /locus_tag="PK679_07905"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit P"
                     /protein_id="HPC55916.1"
                     /translation="MAANYKCARCKQKVEIDVNVRCPYCGHRILFKERGAAIKELKAR
                     "
     gene            12274..12606
                     /locus_tag="PK679_07910"
     CDS             12274..12606
                     /locus_tag="PK679_07910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex subunit Pcc1"
                     /protein_id="HPC55917.1"
                     /translation="MQEQGCGLPGSAKAVESPGFREVSTEHEAIFWFTDARAGTLFRA
                     LNPEVSEELHPRSHAECTLEDHRTLVLKVRARDIPALRASLNMWLRLINVADEMQAFA
                     PRETEERP"
     gene            12603..12965
                     /locus_tag="PK679_07915"
     CDS             12603..12965
                     /locus_tag="PK679_07915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prefoldin subunit beta"
                     /protein_id="HPC55918.1"
                     /translation="MNTISPKIQNQIAQLQQMQQQMQTIGAQKSQYELAVREARRATE
                     ELKDVPDDNAVFMSVGSVLMQKKKEEVLAKLNEKIETLELRIKSLEKQETLLQGKFEQ
                     LQAQVKQALEGKPAPGAA"
     gene            complement(12996..14537)
                     /locus_tag="PK679_07920"
     CDS             complement(12996..14537)
                     /locus_tag="PK679_07920"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HPC55919.1"
                     /translation="MWGIVFFVASEGQRRVTVFDTTLRDGEQTPGISFTFEQKLEIAR
                     QLSSIGVHAIEAGFPASSQGEKETVKAIANLGLDSKICGLARSRREDVDACIDCGVDM
                     VHVFIPTSEVQRVHTIKKSREEVLGITGEIVSYVRDHCDLCMFSAMDATRTERDYLVE
                     VFRTAADAGATILNVPDTVGVSTPMAMRDLILHLAREIDCPLDVHCHNDFGLAVANTI
                     TAVEAGASQVQVTVNGLGERAGNADLSATVMVLESIFGIGTGIRKEKLVETSRLISRY
                     SGIAIPPTYPIVGDNAFSHESGIHSHGVIACAATFEPGIMTPEMVGHRRRLTLGKHVG
                     RHAVRQMLEEVHLHPTDGQLDRIVEKIKFISVKGKRVTDADLYEIAESEMGVGNGGRF
                     IEMDEFAVMTGNHVIPTASIKARIGGKESVYSATGTGPVDAALKAVLGMLPVRVHLKD
                     FHVEAISGGSDAIGHVTIAVEDEHGRVFDASASGDDIVLASTEAMINALNLLHRLDAP
                     TGKGN"
     gene            14666..14772
                     /locus_tag="PK679_07925"
     tRNA            join(14666..14703,14737..14772)
                     /locus_tag="PK679_07925"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14700..14702,aa:Tyr,seq:gta)
     gene            14800..14872
                     /locus_tag="PK679_07930"
     tRNA            14800..14872
                     /locus_tag="PK679_07930"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14834..14836,aa:Asp,seq:gtc)
     gene            complement(14962..15291)
                     /locus_tag="PK679_07935"
     CDS             complement(14962..15291)
                     /locus_tag="PK679_07935"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC55920.1"
                     /translation="MVGERLMMQNASPGPPLEPLLRDLAAAGIDARWRAARMLSARGN
                     DAVDALIRCLYSNDPGCRLLAAWALGNIGDRKALPFLERLTEDDEPDVRLACECALGK
                     IVRISPF"
BASE COUNT         3255 a         4429 c         4640 g         3111 t
ORIGIN      
        1 ggtccatcgc gagcaggaca tcgccgagag ccacccaccg gggggcagaa gacgggtcga
       61 gtgcaaggga ccggttcaat gactcgaaag cttcgctttc cctgcccatg aggtgcaggg
      121 cttttccgcg tccttcccag gcttcaacat tttccccgtt gatcgcgatt gcccggtcga
      181 acagcacaag cgactgctcg aggttcccct gttccaggag cctgtctccc tccctggcga
      241 gatcggcgtc cgggtaagag acgcaagccg caagaaaagg gacgaggacg accaggacgg
      301 cgagcagcca gggaactttc tgcatccata caccatcgac tgcgcaccac ttaatgcatg
      361 cggaaacaca gggtttgagg ggttatccgg agagttggat cgtgggaaag gcgaagaaaa
      421 agagagatgg atggatcagg gaatctcacc cgattcaata ccggcgtacg cctgacccgt
      481 agctcatcgt cttttcgaag gactggatgg tgcctgaagc ggtcgtcttc tcggatccca
      541 tgatatccat ggacttgttc agggagtctc cccgtgcact ctgcaggtgc atgcggtaat
      601 atgcagatgc cgttccctgg cccgcaaggc tgatactgta gtccatggcg accgggacat
      661 cagcttttgc tgcaacgtgc ctctcgctcg caatcgtcgt catggagact gatgtcccgg
      721 agaatgaact tcccatctcg acgatgttgc agtatgcagg gatcgtgtca cctgaagaag
      781 ctccaaacgg acacaggatc ctgtccgacg ccggagaacc catgctggca ccgtcgaggg
      841 caaggctctc gctcgagata acgctgccgt acgcatcatt gaaactgacg aaatccagct
      901 gcctcactga cttgaaatta ttctggttca caacctggtt gcccgtgtcg aggtctgcca
      961 ccttgttgta ttcgacgtat ccgttgttcg cgttcgtgga ctcggaatac gacatggtgg
     1021 cctggcgctc tgatgcgctc aggtacgtgt tgtcatcgag agccccgctc gactgctgcc
     1081 agacgatgga ggcttcgttc gagaaagtac catacacgac aacggaggtc tccgtgtgga
     1141 tggactgcgt ctcgaacgtc gcgttcatgg ggtcgtctgc actcgcatat cccagcagga
     1201 aaaatgccag gagaagaacg aagagtcctt tttttaccat ggataaacac cttgtttctc
     1261 tgtatcgcgg aaattgttaa agattattga catctactcc gatattaact tctaagtttc
     1321 tcatagggtg ggaaaaggta tattgtcgtt caggacctgc ccgaactcca gtggtattcg
     1381 ataaaatatt tcatgatcgt tcccgatgca gtggtctgct gggagaagga gaccgatttc
     1441 gatgctccct gcatcgttcc ccgcatgaac gatgtggcag tcccgatacc ggagatgtct
     1501 gcactgtaac tcgttgtcac cggtttgaga acacccgaac cgacaaagcg gtcccctgcg
     1561 atcgttgtca tggagacaga tttcccggaa aacgaactgc ctgcttcaaa aacattgcaa
     1621 aaatcacctg cgtatgctgc cgaaacggta ctgaccgcga gcaggagcaa cagcaatgca
     1681 ccagttacta tgtatttcat tatccctcct ccttacatta cgtatgtgta ttttttgatt
     1741 agtatttcct tcacactgca tttaaatttt ttccacttcc tggttggata atgagctcac
     1801 atcacaatat taacgtggtg cccgaatgat ttcgggatat tacacctgag ataacaaaga
     1861 aggaaaaaga aaatttaacc ttttaatcag ggaaagcgaa aggcgtcatc gagcgtcttt
     1921 gcagaggaag gtttccaggc aggaagtgtn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnng ccgggtgtat tctcttcttt tgaagagttc ttaccgtgtt ttccagaatt
     2101 atccggatat tccggggaag agacagatgg aaaagaaccg aaagataaaa aaatgggagg
     2161 ggagtttttc tccccccttt ttcaggtcgc tctactgaag atttcagtag cggcggacac
     2221 cggactggta gttgatcgcc ttggtgaagc tggtgatcac accagatgcg gtggtcttct
     2281 cagaggcgac gatgtcgagt gacttgttag cggagtcgtt tccgcgtgcc tcctggaagt
     2341 gtgcacggta gtatgcagat gcactgccct gaccggcaag gccgacgctg tagtcaacga
     2401 cgaccgggac atcagcggac ttggcgacgt gcctctcgtc agcgaccgtt gtcatggaga
     2461 ctgcggtgcc ggagaaggtg ctgccgacct cgatgatgtt gcagaatgcc gggaagtcag
     2521 ctgaggatgc accgaacggg cacaggaact tgtcagccgt ggtggtgttc attcctgcac
     2581 cgtcgagcgt gagtgactcg gcagttgcta cctggccgta tgcatcgtta taggacacgt
     2641 agtcgagctg cttggtggtc ttgtagttgt tggtgttgac taccttgttt gcagtgtcaa
     2701 gagcacttcc agcgttgaac tcggcatacc cgttgttgcc ctggacggac tgggtgtatg
     2761 ccatcgtgta ctggacctca ccatcgtcga gggatgctcc agtgatatcc tgatcgctca
     2821 ttgtccacac gatgctctct gcgttggtga gtgcgccaga gacgaccact gcagtgctcg
     2881 tggtgactcc ctgagtctcg tatgtctggt tgaccggtct gtctgccatt gccatgccta
     2941 cggcgaggaa ggcaagggca aggaccgcaa ttgcgaattt cttcattatg ttcctcctac
     3001 attttatgct gatactctca gcatcaacca gacattttga tcccggttac ataagaactt
     3061 ttctctcttt ttcccaccaa tcggggtgtt tttcagaata ggaaacacct gatttccccg
     3121 attcctgata ttcccctccg tacagggtcg cgggagtatc gtccgttccc gggggaccgg
     3181 cggaagggaa acgattgccg ccattacaac ggagaaaaag caggaattgc atggattggg
     3241 ggacatttcc atgacctcac ttccttgcca ccgtgacgta tcccgtgtgg cacacgcggg
     3301 ttgagggacg cgtccccctc gggcccctcg cgatctccct cccgatgcac tcgtgtgccg
     3361 tcacttccgg aaaaagtccg ctcgccgtat ccatgacggt gaacagctgc tcgaggaacg
     3421 gtgtataaca ggcgaggtat ccgcccggta caaggagtga ccacgcgtgg cggatgatgt
     3481 caggcgagac gtggaggtcg aggtgcacga cgtcgtaggt accggaagcg tcggctacgt
     3541 caccgcagac gacctgcacg ttggagagtt tcgcatcggc aacgttcttt tcggcctgtc
     3601 gggcaaactc gggccggatt tcgtacgtca cgactttccc ggcaactccc ccgaagtaaa
     3661 tggcagcgat cccactcccg gtcccggcat cgaggacgcg gtcattcctg ttcatcccgg
     3721 tgcaggcgat gacaaggccg atgtccttcg ggagcatggg tgccccgctc ctgctcgcac
     3781 gggcaaagaa gtcaggagcc cggggaacga ggacgcggaa ctcctcgccg gtatgcgtcc
     3841 gcacaatgtc acccggggat gccgtgagga gtgcatcgag gtcgaggacg cccctgtctg
     3901 tggaaaagga accggtcccg gcccggacaa agaacgtccg ccccctgccg gcaaggagga
     3961 cgcggtcgcc cgaatcaaac atgttctgac agctggatga tggcggcagc gatgtccccg
     4021 ccggtacgga tgagtgcatc ccgcgccgcc tcggggctga caccggcctg ctcggcgacc
     4081 atcctgacgt cttcgtcagg gatttggggt gctgccggtt caaagtgcgg gttgcccgtg
     4141 atctggtagg tggttatgcc ctgcatggtc atgacggcaa cttccgcaga gtcaaagaca
     4201 taatcacccc tgccggtgga gatgacgatt ttccgcacgt cctctatcgg ctcgacctgc
     4261 atccccagct gtttcatcat ctgcttcatc tttctcgggt tgatgtttcc cggcatcatg
     4321 cgtctttgca ccctggcgta cttttaccgc tacaccgtaa ttaaacacca gtatctctgc
     4381 ccccgagagg accgccgtgc ccgtggcaca gagcgcgtca tcgccggtga caaccatgac
     4441 ctcgtcgcct gcccggatct ccgggtctgc cgagacgaca tgcctgcaga agacgttctt
     4501 cccgttacgg gcaaaatccg caacatcggg gagtatgccg accctgtatg ccgggggcgg
     4561 gatgacctcc atgagccggc gggcaccggc aatcccgagc gtcaggcgcc catcggaggc
     4621 ccggactgtc gcaagcctct gccctgactc cggatcgagg acctggcgga cacgccccgt
     4681 ccgggagtaa acaaacgtgc agccatccgg aaagaggccg cgtcccgctc ctctcccgaa
     4741 ctggtagtca gcaatgaccc tgacgcgggc gagcgaactg ctctccgatg agctggttga
     4801 cccgttcgac aaacgtatcc tccgattccc gtggtatgta cgctccggcg gcaatccggt
     4861 gccctccccc cgcgcctccg acctcggctg atgcgatcgt cagtgcctgc tggaggtcta
     4921 tcccgcgcga cacgaccctc tcggtggtac gcatggatac cttcgtaagg gacgtgtcct
     4981 cgggctgcac gaccatgacg aggatgggct tgtccatgtt caggcgggag agcgccatcc
     5041 ccgccccgat ccccacgatg gtgtcggggt accggtcacc gacgtggatg tactggatat
     5101 gggaaagttc ccggacgccg gtatcgagga tgtactcgag gagctccctg ataacggcgc
     5161 ggtggttgga gagcatgtgc tcggcctccc ggaacgcctc tccccggtcc cccctgcaga
     5221 tcgcgccacc gacacgcggc ctcgtccacc tcccgcacgc attgagaagt gtcgcaaact
     5281 cctgggcgtt ccggagcggg gtccgttccg cctcccccgg gaagaggtag ctctcgcaga
     5341 acagcctgtc ggtcggctca ccgcaggcaa tcagctgctg ggcgagggag cttgtgacca
     5401 gcctcttttc atcgggggaa aattcctccc atacccgcca ccgtttctcc ggggtctgga
     5461 gttcaattcc gagccgctgg aggaagcgga gggccccgct cgcgttgttg gagattcccg
     5521 ggatgtaggg gtcgtcgttg taggcgaggc agacgtggag cgggcgggtc gagatgccgt
     5581 agcagtttaa gtcccgcggg acgatctcga tccaccctgc ctctgcccct tcgatcgcga
     5641 tctcgcgggc gggcccggta agcccgcagt cttccctcgc catcatgtcc ccgacgttgc
     5701 cgacgacggc aaggcgcgag aggtcggcgt tcccgctgtc catctcgcgg gccaccatgt
     5761 atgcaacacc cgccgcactc atcttgacat gcccggaaag caggctgttt gcctgcaggt
     5821 aatccctccc gcagggctgg ctgacgtggt ggtcgatgat caccacctcc tcccgggata
     5881 gcccgcgttc caaaaggagg ttctgctggc cggcacccag gtcgcagaag accttgaggc
     5941 tgtcgtcttc gggaacctgc ttcatcgtca ggggttcgag ctgccgcacg aaaacggact
     6001 tgtgggggac ctctgcacgc gacaatgcct gggcgaggat ggattcgccc gcgatcccgt
     6061 ctgcgtcgat gtgcgagatg acagtcactt cgtggtgcga gaggatcacc ctggcgacct
     6121 cgcgtgcgtc atcccgaagg ctcattggaa tagtactgca cgatggagga gaaaagggtg
     6181 accatccccc atgggagaat gtgccctttt agtccgtcct tttcccggac cggaacaccc
     6241 ccggggcagg cccgcgcccg cctccagact gcggggtatg gggcagagac cttcattatc
     6301 cccggaagag ttaccactta cacgggaatg cagggaaacg acaggagggg ctgcatggtc
     6361 cggccggaat gccgcgagtt catggagacg gggatcgtgt ccccggagag gatgcgggca
     6421 atcgatgcaa acgcccgtgc actcggcgtc tcatctctcc agctgatgga ggctgcgggg
     6481 tatgcactgg ccggttttgt caggtcgctg ggacgcggcc cgatcctctt tctctgcggg
     6541 aagggcaaca acgggggtga cgggcttgtt gccgcacgcc acctccagga cgaagacgtc
     6601 acagtcctct tcctcgacgg ggagggccgg agcgcggagt gtgcatacca gctccggtcc
     6661 cttgcgcact gcccggtccg gtgcatcccg gtccgctgcc ccggggacgc aacggcagaa
     6721 aagaggatct ttgaagaggc ggggtgcatc gtggacgcac tcctcggcac ggggagccgg
     6781 ggtgagcccc gggaacccgt ccggacactt gccgggctcg catcgctctc ccctgccgtg
     6841 aaggtatctg cagacgtccc gacgccggga tttgtcccgg accgtatcct tgccttccac
     6901 aggccgaaag tggaaggatc cgtcgtggcg tccattggaa tcccccttgc ggcagagatt
     6961 accgtcgggc cgggggatct cacactcgtc aggaagaaag atccctctgc acacaagggg
     7021 gcagggggag aggtactcgt cgtgggcgga gggccgtacc agggtgcacc atacctcgcg
     7081 gggcttggtg cccttcgggc cggtgcagac atcgtgagga tcgcctcgcc cgtcttcgaa
     7141 cccgttccgg acctcatcta cgagcggctc gagggaaagg tgattgcagg ggagcacctc
     7201 gaaaggctcc gggaactggc gcggaccgcc gatgttgttg tcatgggaaa cggccttgga
     7261 gaccggagcc accatgtcat ggtcgatctt gcgaaggagt gcccaaaggc tgtcgtggac
     7321 gcagacgccc tgcggcgtcc actcccccgc gcggccgaca ccatctacac gccccatgcc
     7381 ggcgagttcc ggagggcatt ctcccgcgaa ccccccgacg acatcatcgg gagggcaaga
     7441 gccgtgaaaa aggcggcagg agagggtact gtccttctca aggggcgggt ggatattatc
     7501 tccgacggtg caagggtcag gttcaaccgc accggatccc cgatcatgac agtcggtggg
     7561 acaggtgaca tccttgcggg tgttgcgggc gcgctcttct gtaagctgcc cgcgttcgag
     7621 gctgcatgca tcgcggcgta cgtgaacggc agggcgggaa tggctgtcga agaagcaatc
     7681 ggcggcggca tgctcccgac cgacctcctc gaccgcatcc cgctcgaact ctacaggaaa
     7741 gaggagaccg aatgagagaa ttttcgcata tcgaggacga ccgtgcccgg atggtagaca
     7801 tcagcggcaa gggcgaggtg taccgcgagg ccgttgcctc cgggaggatc gtcctccggg
     7861 aagagacgct ccgtgccatc cgcgaaggga cggttgtgaa ggggaacgtg cttgcgaccg
     7921 cccgcgtggc ggcaacgctg gccgtgaagg ggactcccgc cctcatcccc atgtgccatc
     7981 ccatcccggt cagcagcatc gaggtggatt tccatgaccg cggggactcg atagaggcat
     8041 gcgtccgcgt gcgttcgctc gggcggacgg gcgtggaaat ggaagcgctc acgggtgtct
     8101 cggttgctct cctgacaata tgggacatgg tcaagtcggc ggaaaaggac agccggggcc
     8161 agtatccggt gacatgtatc accggtatca gggtgctcga aaagaggaaa ggcgaaccca
     8221 tcggggaaga gtgaccggaa agggcactct ccattcctgc aaccgcgcac tttaagtgcg
     8281 tccctgccga ttcatatagg tcttacggga tgcgtcccgt caaggaatgt ggcccggtct
     8341 tccgggctga acctgaaagg tgtaaaaatg gcacgatcaa tgtatgccta cgtcagagag
     8401 gcatggaagc gacccgcaca aacaggtgtc gacgagctcc tctgggagag gatgcaggta
     8461 tggcgccgcg agggcagcgt ggtccgcatc gaccgcccga cgcgcatcga ccgggcccgg
     8521 aacctcggct acaaggcgaa gcagggcatc gtgatggtca gggtcaaggt ccgccgcggt
     8581 ggcaggcgca agtcccggta cgtccgggcc cggcgctcca tacgaatggg cgtcaacagg
     8641 atcacccctg caaagagcct gcagaggatg gccgaggagc gtgcatcccg caggtacccg
     8701 aacatggaag cactcaactc ctactgggtc gggcaggacg gcaggtacaa gtggtacgag
     8761 gtcatcatgg ttgacgggca ccacccggca atccggaatg acagccagct ctcctggatg
     8821 ggcgatgccg tccaccgggg ccgggcggaa cgcgggaaga cgagtgccgg caggaaaggc
     8881 aggggcatgg gtacccgcgg gcgcgggacc gagaagaccc ggccgagcat ccgctcgcac
     8941 gggaacctgg gcaaataact aaaatccttc cctgcccaga tcttttcttc tccatgcaat
     9001 gcactgacgc ctgcgtcttt ccctaccccg ggggagactc ttccctccgc aggatggccc
     9061 tttcggcccg cgaactcggt tttgacagca ttgtcgcggc ttgtcccgcg aacgggacat
     9121 actgcggtgt ggaagttatt ggcatgaagg tcatgggacg gacgggggca ggggcaaaag
     9181 aggtatccca cgcggagccg ggtcaggaag gccgggcaat taccgtggcc catgcgggtg
     9241 aatacgcagc aaacagggca ctcctccgca ccggcaagat catggtcctc cgcggtatcc
     9301 agtggactcc caagaactct ttcgatcaca tcctctcccg gatggcagca gagaggggca
     9361 ttgcagtgga catcgatttt tcgtccctca tctgcgaaag gggctcgtcc cgccagcggg
     9421 tcatccagcg ctatgccgac atcgtccgtc tccaccggaa attcgggttc tccctcacgc
     9481 tctcgtccgg cgcccgatcc gttctcggga tgcggtcacc gcgggagatg accgtgctgg
     9541 gggggttgtt cgggcttgaa gaagacgata cggggagagc actcggaacc gtccggcagc
     9601 tgctcttccc ccgcagtccc gtcgaggtgg tggaatgaag cctcttcctc cgacactcag
     9661 ggaaaacagg cgttacgtgc tcgtgcggat cgaacccccg tggttcgaga ctgacagccg
     9721 cacactctac ggcgctcttg cagaatccgt cacagcactt tttggtgata cggggatggc
     9781 acggattcag cctgcagtca tatctgcaag ccggggcttc gcaattgtca ggtgcatacg
     9841 gtcgacggag gacgaactcc tcgcggggct ggcggcggtt caccatgtcg gatcccagaa
     9901 agtcgccctc aggagtgtcc gcacatccgg gaccctgcgt gccctccgga gtaccattcg
     9961 ggaaggccgg ttctgccctg ccatggagac gggagaggcc cggttcgggg gaaaaacgta
    10021 cgaaagtgtc agttaccagc ttgaaaaggt tgatttattt gaaaaaggat ttaaaagcca
    10081 ggaaccattg tttctcacag ccgaggatct ggaggaataa cgatgcaacc acaagcatac
    10141 cagatgggat atgaccgggc gataaccgta ttcagcccgg acggccgcct ttatcaggtc
    10201 gaatatgccc gggaagcggt caagaggggg acaaccgcgg tgggaatcaa gtgccgcgac
    10261 ggggtcgtgc tgatcgttga caagcgtgtc agctcccggc tcctcgaggc ctcctcaatc
    10321 gagaagatat tcaagataga cgaacacatc ggggtcgcct catcgggact cgtcggggac
    10381 gcacgtgcgc ttgtcgacag ggcccggatc gagtgccaga tcaaccgcat cacgtacgat
    10441 gagaagatcg acgtggaggc tctggcaaag aaactcgggg atcacatgca gacatatacc
    10501 cagttcgggg gcgcaaggcc gtacggcact gccctcctca ttgcaggcgt gagcgacggg
    10561 gagtgcaggc tctttgagac cgacccgagc gggaccctcc tcgagtacaa ggcaacgggc
    10621 atagggatag gcaggaatgc cgtcatgaaa gtcttcgagg aggaatacga ttatgatacg
    10681 ggcatcaatg agtccatcct ccttgggatc aaggcgctcc acgacgcgac cgaggggaaa
    10741 ttcgatgtca ataccgttga aatcggtgtt atcgagcggg agaacccact gttccgcaag
    10801 atgagcaagg aagaagtcga ggcattcgtc gagaagttcg agaagtaggg gggcggaccg
    10861 gatgataccc ctcgagaagg cagtctgtgc aaggctggaa agccacggcg agaagttcga
    10921 gatcctcgtc gatcccgacc ttgccgtccg gttcaggcag ggagaggatg tgcccctgga
    10981 ggagatggta gcagcccttt acgtcttttc caatgcctcc cgtggaacga gggcctctga
    11041 agaatcgctc gaaaaggtat tccagactac ggagttttcc gagatagccc cccggatcat
    11101 ccggaaggga gagatccacc tcaccgccga gcagaggcgg cagatgattg cggacaagcg
    11161 ccggcaggtc atccacttca tcgcaagaaa cgccatcaat ccccagacag ggctgccaca
    11221 tcccccccag cggatcgaga tggcgatgga ggaggcgcgt gtcaacatcg acctctacaa
    11281 gagcctcgac gaactcgtga aagagacggt caaggcactt cgtcccatcc tgcccatcag
    11341 gttcgaggag ctccggatag cggtaaagat accggcggat tttgcccccc gggcattcgg
    11401 agagatacag tctgcggcaa ccatcgagcg ggacgagtgg cagaaggatg gttcatggat
    11461 atgcatcgtc cggatccctg cgggtatcca gggtgacttt tacgggcttg tcaacaggat
    11521 atcgaaggga cagggagaag tgaagatcct cgattaagta tatcaggaaa tactgcgaat
    11581 aataaaagac cagaagagaa acaggggaag gaaccatgag cagtggacag cagaaggcaa
    11641 agggaagggt aacgggcagc gcagggcgtt ttggaccgag gtacgggagg ttcatccgga
    11701 agagagtcac cgagacggaa aagatctccc gtgcagccca ccgctgcccg cggtgcgaca
    11761 ccatggctgt aaaaagggtt ggcaccggga tctgggcctg ccggaaatgc ggttttaagt
    11821 tcgcgggcgg tgcctacacc ccgcagacac ctgcactccg catcgctctc cgtgccatcg
    11881 acaggacggc aaccgacatc tcggagtgat agcctgatgg ctgccaacta caagtgtgcc
    11941 cggtgcaagc agaaggtcga gatcgatgtc aacgtccggt gcccgtactg cggtcaccgg
    12001 attctcttca aggaacgtgg tgcagcaatc aaggaactga aggcgcgctg acggttcacc
    12061 ctttttccgt tcctgtttcg atcgatctct ctcctttttt tacacggttt cccggattcc
    12121 cgcttttttt taccctgaaa aaagactctg cccctccgat tgaggagacg ccatctttaa
    12181 cggaccgttc tccggtgcgg agaacccgcg tggggatggc cccgggggaa caactggttt
    12241 aaaggtgccc gcgtccacct aaatacagta cagatgcagg agcagggatg tggactgccg
    12301 ggttccgcga aagctgtgga aagcccgggc tttcgggaag tgtccacgga gcacgaagcg
    12361 atcttctggt ttacagatgc ccgtgcggga acgctgttcc gtgccctgaa ccccgaagta
    12421 tccgaagagc tacacccccg ttcccatgcg gaatgcaccc tcgaagacca caggacactt
    12481 gtcctgaagg tccgggcaag ggacatcccg gcattgcggg catccctcaa catgtggctg
    12541 cgcctgatca acgtggcaga cgagatgcag gcgttcgccc cacgggagac agaggagaga
    12601 ccatgaacac catatcgcca aagatccaga accagattgc ccagctgcag cagatgcagc
    12661 agcagatgca gaccatcggg gcacagaaga gccagtacga actcgccgtg cgcgaggcaa
    12721 ggcgcgcaac agaggaactc aaagacgttc ccgatgacaa tgccgtcttc atgagcgtcg
    12781 gttccgttct catgcagaag aagaaggagg aggtcctcgc aaaactcaac gaaaagatcg
    12841 agacgctcga gctccggatt aagtcactcg agaagcagga gaccctcctc cagggtaaat
    12901 tcgaacagct ccaggcccag gtcaagcagg cactcgaggg caagcccgcc cccggtgccg
    12961 cctgaaaaag atccctgcaa aaaagggctc tcttttcaat tcccctttcc ggttggcgca
    13021 tccagccggt ggagcaggtt cagggcattg atcatcgctt ccgtggaagc aagcacgata
    13081 tcgtccccgg aggcactcgc atcgaagaca cggccgtgct catcctcgac agcgatcgtg
    13141 acatgcccaa tcgcgtcaga cccgcccgag atcgcttcca cgtggaaatc cttgaggtgc
    13201 acccggacgg ggagcatccc gaggacggct ttcaatgcag catcgacggg tcctgttccc
    13261 gtcgcgctgt agacagactc cttccctccg atccgggcct tgatgctggc cgtcgggatg
    13321 acatggttgc ctgtcattac tgcgaactcg tccatctcga tgaaccgtcc accgttgcca
    13381 acgcccatct cgctctccgc gatctcgtag aggtcggcat cggtgactct cttgcccttg
    13441 accgagatga acttgatttt ctccacgatg cggtcaagct gcccatcggt cgggtggaga
    13501 tgcacttcct cgagcatctg gcgtaccgcg tgtctcccga cgtgcttgcc gagcgtgagc
    13561 cgccggcggt gccctaccat ctccggtgtc atgatgccgg gctcaaacgt tgccgcgcaa
    13621 gcgattacgc cgtgggagtg gatcccgctc tcgtgcgaga acgcgttgtc cccgacgatg
    13681 ggatacgtgg gggggattgc aatgcccgag taccgggaga tgaggcggga tgtctcgacg
    13741 agtttctcct tgcggatccc ggtcccgatt ccgaagatag attcaaggac catcactgtc
    13801 gcagagagat ccgcgtttcc ggcccgctcc ccgagaccgt tcacggtcac ctgcacctgg
    13861 gaagccccgg cttcgacagc ggtgatcgtg tttgcgacgg caagcccgaa atcgttgtga
    13921 cagtgcacat cgagcgggca gtcaatctcg cgggcaaggt ggaggatgag gtctctcatc
    13981 gccatcgggg tggagacacc gacagtgtca gggacgttca ggatagtcgc acctgcatct
    14041 gcagcagtcc ggaatacctc gacgaggtaa tctctttccg ttcttgtcgc gtccattgca
    14101 gagaacatgc acaggtcgca gtgatcccgg acgtaggaaa cgatctcgcc ggttatcccg
    14161 agcacctcct ccctgctctt tttgatggta tgcacccgct gcacctcgga ggtcgggatg
    14221 aagacgtgaa ccatgtccac tccgcaatcg atacatgcat cgacatcctc ccgccgggac
    14281 cgggcgagcc cgcagatctt tgagtcaagg ccgaggttgg caatggcctt cacggtctct
    14341 ttctcgccct gggacgaggc cggaaaaccg gcttcgatgg catggacgcc gatagaggac
    14401 agctggcggg ctatctcgag cttttgttca aaggtaaacg agatgccggg cgtctgttcc
    14461 ccgtcccgga gggtggtgtc aaaaacagtc actcttcttt ggccttcgct agcgacaaag
    14521 aagacaattc cccacatcag tggttctgga ggtcatacct taaatttggt gtcccgacca
    14581 cttaaatgta cgtcccattt gcagggaaat cccgctgtat cgatacgttt aataggttta
    14641 ttacccctat agtatgagcg caaatcccgc cttaactcag actggtagag tgcgcggctg
    14701 tagtatgatc tgccggtatt cggcaattgc gcggctaccg cgatgtcccc ggttcgaatc
    14761 cgggaggcgg gatccccaac ctttgcgcag tatcggtatg cccaggtagt gtagtggcct
    14821 atcatgtcgg cctgtcacgc cgacgactcg gattcgaatt ccgacctggg cgttcctttt
    14881 tcatgttata gtggggatgc tggcaggtat tcataagagt gtcagtaatc tcagatgact
    14941 tccaatgaaa tggagattat cctaaaaagg ggatatccgc acgatttttc ccagtgcaca
    15001 ttcacaggcg aggcggacat cgggttcatc gtcctcggta agtcgttcga ggaagggaag
    15061 ggctttcctg tccccgatat ttccaagggc ccatgcggca agaagccggc agcccgggtc
    15121 attgctgtat aaacacctga tcagggcgtc cacagcatcg ttaccccgtg cagagagcat
    15181 ccgtgctgct ctccagcggg catctatccc ggctgctgcc aggtcccgga gaagtggttc
    15241 gaggggaggc ccggggcttg cgttctgcat catcagtctc tctccaacca tgctatatgt
    15301 taacacccgg caatagactg actctttatt tataactttc gtcctcggaa aatcgctttg
    15361 aatttggaga ttttcgcact attatccgca ccagaaagcc gggaatcagg tcagggttat
    15421 gggataggtt tatgtaatat caaaagcacc tgtctgacaa gtttttttcc cattacaaaa
    15481 ttggaggacc cttcatttca gtttttaacc attctttatc cagaaaatat aaata
//
LOCUS       DAOOJU010000035        15415 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_3701_length_15415_cov_17.191471, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000035 DAOOJU010000000
VERSION     DAOOJU010000035.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 15415)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15415)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15415
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3701_length_15415_cov_17.191471"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(154..1017)
                     /locus_tag="PK679_07940"
     CDS             complement(154..1017)
                     /locus_tag="PK679_07940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55921.1"
                     /translation="MDTGAPRKTPLLEGVMEVAGLRCIEPSFADLIDDAYTAWLEDVP
                     ADEGRMLVDEGDEPLAFAFHTEQGWLMGSFHLKEPTLALIEHFEEIPGEIFQEERAVF
                     EDAVREYYSLDLARTVTPALDDLNPDRIGKARDLLSEFWKGRSFSSCLDCCCGSGLGS
                     LVLRERGIAPLAYDNDPSLLSLGISRGRLLPEKTMYIDGTLAEHYCRGADAGLGLMFG
                     EINTFNEGTWEAITDALLGLAEYCLITVGTEREADLIRSWGKSRGCRVETAENTRDPI
                     YDRWVCELERA"
     gene            complement(1024..2259)
                     /locus_tag="PK679_07945"
     CDS             complement(1024..2259)
                     /locus_tag="PK679_07945"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HPC55922.1"
                     /translation="MTAHKILFLVLDGISDRPCPELGNRTPLQAAVTPILDGIAAEGA
                     CGIMDTIAPGIRPGSDTAHLSLLGYEPEKYYTGRGPLEAEGCGIHMEPGMIGFRCNYA
                     TLDDQGRVVDRRAGRIHGTEPLSQAIQEGVDLSPLGVEFFFRSGAGHRAALAFRGEGL
                     GVAVTSNDPKKEGVPPLPFEARSGDEADRMTARALAAFVAQAEEILRDHPVNASRRAE
                     GLLPANTVLVRGAGKMGYFEPFSTKYGLSGKVISAAALISGIGTAVGLTRVDVPGITG
                     SVDSDLGAKVRAAREALSSADFVLVNIKGADEAGHDGNVREKVAFIEKIDLALAPLAR
                     LPDTLIVVCADHSTPCSVKDHSADPVPVVIAGEGVRVDRVTSFNEISCAEGGLHRIRG
                     SSLMPILLDLLNRSPKYGA"
     gene            complement(2390..2983)
                     /locus_tag="PK679_07950"
     CDS             complement(2390..2983)
                     /locus_tag="PK679_07950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3ae"
                     /protein_id="HPC55923.1"
                     /translation="MAKKKQSGRRVEGWKAKSWYKVFAPEVLGKTYIGDTIANDPESV
                     VGRILQTTLGEIINDYARQNVKMKFKIANVAGDSAYTEFVGHEITRDYLRSMIKRRTS
                     RIDCHVPVTTKDGKRVDLTVTCFTLTRANLSQAHEIRSIISSMISKMGSEADMNGIIS
                     GIVNGDFSREVFKAVKPVFPVRRVEVIKSKLTTAKVV"
     gene            complement(3050..3343)
                     /locus_tag="PK679_07955"
     CDS             complement(3050..3343)
                     /locus_tag="PK679_07955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex subunit Pcc1"
                     /protein_id="HPC55924.1"
                     /translation="MMEIRGILRTRHSRAECIAASLRPDNLQSMRTWSEGGQVVTEIR
                     GDSLRSVIASVDDYLMNLAIAEDLCSLVPEKGEERAPAPRRPKPPCDGQGETR"
     gene            complement(3340..4560)
                     /locus_tag="PK679_07960"
     CDS             complement(3340..4560)
                     /locus_tag="PK679_07960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HPC55925.1"
                     /translation="MTLAEAAAHLAGHIARQEFVEVYAHHDADGIAAGAIVCMALLRK
                     GIRFRLRVVSHISPATLSPETPALLCDLGSGIPDLPPEVMVIDHHVPRFSGALQVNPR
                     LCGVDGERELSSAGAAFLVAQALGDNRDLAGLVMLGIIGDGQQLAGENLAIFNDAVAL
                     GLVSPGKGLLLAGRDDHERLYGALNPYLHQVSGDEMAVSDLLESAAGDGKVSLDKLLS
                     LIVLRVAPYAPVKTLESLYGDCYSLQREVVPDAHTLTAVVDACGKSGHGGLAASLCLR
                     STAGLDEAYECTIRHRLNVIRALRSCWEQKDVSGVVEVGDPSVASDVADAFSRDCLHD
                     RPVVAVAAQKDDLAFVSVRVTPGRDIDISEHVHVAAVQVGGFGGGHRQRAGATVPAGQ
                     LSRFMDALQKSVAA"
     gene            complement(4567..5025)
                     /locus_tag="PK679_07965"
     CDS             complement(4567..5025)
                     /locus_tag="PK679_07965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HPC55926.1"
                     /translation="MARMHARRRGHSGSVRPFRKEAPSWANTDVAAIEKIIVDLRKEG
                     MSASRIGLILRDRHGVPDVKLVTGKRISQILKEKGMEPEIPEDLRNLIAKALGLRKHM
                     AENKNDLHNKRQLQLTESKVRRLVKYYTGTGRLPKDWSYKPESAEILLSR"
     gene            complement(5215..6447)
                     /gene="mmp10"
                     /locus_tag="PK679_07970"
     CDS             complement(5215..6447)
                     /gene="mmp10"
                     /locus_tag="PK679_07970"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314610.1"
                     /note="Mmp10 (methanogenesis marker protein 10) is a
                     cobalamin-requiring radical SAM methyltransferase that
                     creates the methylarginine modification to methyl coenzyme
                     M reductase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA];
                     GO_process: GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyl coenzyme M reductase-arginine
                     methyltransferase Mmp10"
                     /protein_id="HPC55927.1"
                     /translation="MAHLTVDIGGRPGVDCRGFCEYCYFKHVRDTPPFGCRYCPPFRK
                     GCDYCSRSVRESYSGFRDLRDVADDVLARLQAIPDEVSRITISGGGDPSCYPRFRDLI
                     ELLASMEAPLHIGYTSGKGFDDPGIADFLVQSGLSEISFTVFSVRPDLRRRYMHDPTP
                     EASLAVLERLCAEIDVYAACVVLPGVNDGPVLEETCRWLEERGAKGIILMRFANRTDQ
                     GLILGNAPVIPGHPVQDVAGFRDMVTALSRKFRIKISGTPLWDPQIGSPFALAAEPDL
                     VAKLPRIGRRASVISGRIAAPYIASILSQCGKGASVVPVEKDIACLITIDDLRALDPR
                     DLEPLVIIPGRAFVYDREAQSVLSRDGVARTILRGPECLTADAETSMGMDRNAVLALE
                     MEAFADLIRLINRYGQPL"
     gene            complement(6505..7020)
                     /locus_tag="PK679_07975"
     CDS             complement(6505..7020)
                     /locus_tag="PK679_07975"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55928.1"
                     /translation="MKVRFLPACLFLLALILCSGCSQPHGGSSGSLPGTQTMTAGSTV
                     PPTPVAISIRATPDRYIPLMSSTVGIRLEPEFSPTIPVIYTWTASYGHFVSWNSTDPR
                     VVIHNATVRTVEPSIYWSYPPQDMGREKPPVRVRLVVETERVTHGGRGTVGYSELFIG
                     WEGNDTAVVRA"
     gene            7367..7762
                     /locus_tag="PK679_07980"
     CDS             7367..7762
                     /locus_tag="PK679_07980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55929.1"
                     /translation="MNRSIYCGCLLLCAALALLAAGCLAPAATGPGAHTAPLPVYARG
                     DVLAGNMTAAGYDTPDPDIAGVRALVLGFEPGSDMYVYTFVRTLPNGSYGYVFSESWE
                     AKLARPRPVFEAYGLGKVGMMAEKYLWKV"
     gene            8029..8292
                     /locus_tag="PK679_07985"
     CDS             8029..8292
                     /locus_tag="PK679_07985"
                     /inference="COORDINATES: protein motif:HMM:NF016352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF504 domain-containing protein"
                     /protein_id="HPC55930.1"
                     /translation="MMRSREVLLQLLHDSRYSLSDAEVWYIDRGAPGNTSRLSGRDIV
                     SVEAFSFGVATENGTKDIPYHRILRILHRGETLWERGMKRDRR"
     gene            8877..8949
                     /locus_tag="PK679_07990"
     tRNA            8877..8949
                     /locus_tag="PK679_07990"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8910..8912,aa:Thr,seq:tgt)
     gene            complement(9645..12692)
                     /locus_tag="PK679_07995"
     CDS             complement(9645..12692)
                     /locus_tag="PK679_07995"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF024754.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HPC55931.1"
                     /translation="MHLNPAQLDAVTRQGIQLILAGPGSGKTRVITEKIRYLISMGVP
                     PSNILALTFSDKAAQEMRDRLDSVPQSADLTVSTFHSFCLSVLEENRLDSGINFSSGV
                     ISRANQLVWGLKNIDSFGFEHIEVGNNAVDVIEAIIDGISAFRDELISPDELAHYLKK
                     KENVTVSAEESAYLEKLSDLIKVYRAYERFKREEMLLDYDDMIHETCRLFERKPLILR
                     RYRERFTHILVDEFQDTNYAQLQLIKMLAGDHLCVVGDDDQTIYRFRGAYLTNMQDFL
                     QHFRDAQVILLTHNYRSTQTILTLALALMRHAPNRREKQLLTDNPPGEPVKVVHCENE
                     TTEASYVIGEIERLLGTRFLSRREKVERPYTYKDFAIICRRRRDGAKFYQLLRDRGIP
                     AEFVGEMEFFSAPVIRDLLAYLKIINNPLTAGIPLNRVMKISGIPETEVQKINAVARR
                     ATFGNPYNDGVFEAMRSIDSLAPHHATAIRELLGTLDALIMEKDRGPLTALVHHLMMQ
                     ATDLYARALEDETGQDILLLNHFLTITREYEEITKDATVDSFLTYLRFLSGFSIEVGE
                     TDVADSVKVLTVHKSKGKEFPVVFVADLAVNRFPLQYQAKEFFVPNDLSKGMKTTHDE
                     KALFEQEERRLLYVAMTRAEDLLYLTRAKWYGNNKNPTKQSKFLDELPLDDPSLVQKV
                     EVPAVVSAPALRGKTALEKYQQTLQYQAKRAIHQLHLQTALQHIVTLEKIRLISEGKD
                     LSSFNRNAFLTFTENDAEIETLMQGRTPCLVGESHTFSASGLSTYERCPLKYKFQYVL
                     QIPSLSRTFFDLGSAVHTVIEHLSKKQREGIAPTKEMALALLDTAWSTAAYESKSHEM
                     KDRATAEALLDTYLTWQAGNPNRILEAEKRFQISLGGRRLNGVIDRIEETPDGEIVVI
                     DFKTGSKPGNLSKNTIRDDIQMNLYSLAIREIYGKLPVKASLYYLGPNKTYDYTPTLE
                     TIGTFEERVVNLIKSICAEEFSPRPDYQTCKWCDYKDFCEEGD"
     gene            complement(12780..13298)
                     /locus_tag="PK679_08000"
     CDS             complement(12780..13298)
                     /locus_tag="PK679_08000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HPC55932.1"
                     /translation="MTKTIAYEVTGHLGDIEFRTYPPLILATVSGTDENEAFTILFRF
                     ISGNNQSGKKVPMTAPVITPEKIAMTAPVLSDAHSMSFVMPATYTRNDIPEPLDMRVS
                     IQEVPSRELAVIRFRGSASDRDVSLVRERLLASLARANISPVGTPFLMRYNSPFTPGF
                     LRRNEVGVEIRR"
     gene            complement(13539..14282)
                     /locus_tag="PK679_08005"
     CDS             complement(13539..14282)
                     /locus_tag="PK679_08005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S double cluster binding domain-containing
                     protein"
                     /protein_id="HPC55933.1"
                     /translation="MTSRIPAHHSFTMSFALGDRIHSLAYSLGAGYYGVADLAPARDF
                     ILRQGGERIARYPRAISIGMQIPDDIVELVPDGDAEAAVIYRHSGYEVLNQALDQVSV
                     RVARELQRAGYHAFPVPASRRTDDREIRSVFSHKLAAHLAGLGWIGKSCLLVTPDNGP
                     RVRWVSVLTDAPLGVTGTPMEPHCGTCTACADTCPKGAITGRMFDPSEPREARLDAAA
                     CDQYFREMEGKKGVAVCGLCLYACPYGKK"
     gene            14408..14668
                     /locus_tag="PK679_08010"
     CDS             14408..14668
                     /locus_tag="PK679_08010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55934.1"
                     /translation="MNTRDIIKRLWDEAGRGNLAIWDDETITVVPQDYPGETGGKRPV
                     AILKPLLLVNKYDFLDFALADEELLTTIEEAIRAGGGRVTRD"
     gene            complement(14665..15382)
                     /locus_tag="PK679_08015"
                     /pseudo
     CDS             complement(14665..15382)
                     /locus_tag="PK679_08015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843740.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
BASE COUNT         3013 a         4419 c         4694 g         3289 t
ORIGIN      
        1 aggacgaaaa ggtaattttt tgataaaacg catcatccgt catttcggag ggggggaaca
       61 cgggggcttt cccgtctccc atttcacgtt tcccggttcc ccgccctgac tccatagaga
      121 acaaaaactt ttttggggta tgcacttccc cgttcacgcc ctttccagct cgcagaccca
      181 ccggtcgtag atgggatcgc gggtgttttc cgctgtttcg acccggcagc cccggctttt
      241 tccccaggac cggatgaggt ccgcctcgcg ctccgtcccg acggtaatca ggcagtattc
      301 cgcaaggccg aggagggcgt ctgtgatcgc ctcccatgtg ccctcgttga aggtattgat
      361 ctccccgaac atcaggccga ggcctgcgtc tgctcccctg cagtagtgtt ccgcaagggt
      421 cccgtcgatg tacatcgttt tttcgggcag gaggcgcccc cgcgagatgc ccagcgagag
      481 gagcgaagga tcgttgtcgt aggcaagggg ggcaatcccg cgttccctca aaacgaggga
      541 cccaaggccc gacccgcaac agcagtcaag gcacgaggaa aatgacctcc ccttccagaa
      601 ctcggagagg aggtcgcggg ccttcccgat cctgtcgggg ttgaggtcat cgagggcggg
      661 tgtgacggtc cgggcaaggt cgaggctgta gtattcccgg acggcatcct cgaagaccgc
      721 ccgctcctcc tggaatatct ccccggggat ctcctcgaag tgctcgatga gggcaagggt
      781 cggctctttg aggtggaacg agcccatcag ccagccctgt tccgtgtgga atgcgaatgc
      841 gagcggctca tccccctcgt cgacgagcat ccttccctcg tcggcaggga cgtcctcgag
      901 ccaggcggtg tatgcgtcgt cgatgaggtc tgcaaaggac ggctcgatgc aacgcagacc
      961 ggcaacctcc atgacaccct cgaggagagg ggtttttcgt ggtgctcccg tatccatggc
     1021 aggtcacgcc ccgtacttgg gcgaccggtt caggaggtcg agaaggatcg gcatcaggga
     1081 ggacccgcgt atcctgtgga gcccgccttc ggcgcaggag atctcgttga agctggtcac
     1141 gcgatcgacc cggacaccct cccccgcgat gacgacaggg acagggtcgg cactgtgatc
     1201 cttcacgctg cagggcgtgg agtggtctgc gcagacgacg atgagcgtat ccggcaatct
     1261 tgcaagaggt gcaagggcaa ggtcgatctt ctcgatgaaa gccacctttt cacggacgtt
     1321 tccgtcgtgt cctgcctcgt cggccccctt gatgttgacg aggacgaagt ctgccgaaga
     1381 gagcgcctcc ctcgcggccc ggacctttgc acccaggtcc gagtcgaccg atccggtgat
     1441 ccccggcacg tcaacgcggg taagcccgac ggcggtcccg ataccggaga tgagggcggc
     1501 agccgatatg accttcccgg acaggccata cttcgtggag aaaggctcga agtatcccat
     1561 cttcccggct cccctgacaa ggaccgtgtt tgcaggcaaa agaccctctg cccgcctcga
     1621 tgcgttaacg ggatggtccc ggaggatctc ttctgcctgg gccacgaagg cggccagggc
     1681 ccgggccgtc atcctgtctg cctcgtcccc gctccgtgcc tcgaagggga ggggcggcac
     1741 accctccttc ttcgggtcgt tcgacgtgac cgcgacaccg agtccctctc cccggaacgc
     1801 gagggctgcc cggtgcccgg cgccggaacg gaagaaaaat tccacaccca gcggggagag
     1861 gtcgacgccc tcctggatgg cctgcgaaag gggttctgtc ccgtgtatcc tgccggccct
     1921 ccggtcgacc acacggccct gatcgtccag cgtcgcgtag ttgcaccgaa atccgatcat
     1981 gccaggttcc atgtggatac cgcagccctc ggcctcgagc ggccctctcc cggtatagta
     2041 cttttcgggt tcgtacccga gcaggctcag gtgggccgtg tcggaaccgg gccggatacc
     2101 gggggcgatc gtgtccatga tgccgcaggc accttcggcc gcgatcccgt cgaggatggg
     2161 ggttactgcc gcctggagtg gtgtccggtt gccgagttcc gggcagggcc ggtcggagat
     2221 gccgtcgagg acgaggaaga ggatcttgtg tgccgtcatg acagggaagt tttgtcacca
     2281 cgctcactta tgtttcaccc ccgccggatg ccgggaggaa aaagggcgcg tgcccctcct
     2341 cccgggagcg gtgagaaaaa agatgtttcc aaaaaaaggc ggtattttcc tacacgacct
     2401 tggccgtggt cagctttgac ttgatgacct cgacacgccg gaccgggaag acgggcttga
     2461 ccgccttgaa gacctcgcgg gagaagtcgc cgttgacgat gccggaaatg atcccgttca
     2521 tgtctgcttc cgatcccatc ttcgagatca tcgaggagat gatgctccgg atctcgtggg
     2581 cctgggagag gtttgcacgg gtgagcgtaa agcacgtcac cgtgagatct accctttttc
     2641 catcctttgt cgtgaccggg acgtggcagt cgatgcgcga cgtgcgcctc ttgatcatcg
     2701 accgcaggta gtcgcgggtg atctcgtggc ccacgaactc ggtgtacgcc gagtcccctg
     2761 ccacgtttgc gatcttgaac ttcatcttga cgttctgccg ggcgtaatcg ttgatgatct
     2821 cgcccagcgt ggtctgcagg atccgcccga ccacgctctc cgggtcgttg gcgatcgtat
     2881 ccccgatgta ggtctttcca aggacctcgg gtgcaaacac cttgtaccag ctcttggctt
     2941 tccagccttc cactcgtctt cctgattgtt tcttctttgc cattgtatca ccaggttccg
     3001 tcctgtcttt cttctttttg tccttccctt cggggcgttg tccgccctgt caccgggtct
     3061 ctccctgccc gtcgcacggc ggttttggcc tgcgcggagc cggggccctc tcttctcctt
     3121 tttccgggac gaggctgcag aggtcttctg caattgccag gttcatgagg tagtcgtcca
     3181 ctgatgcgat caccgaccgg agcgagtctc cccggatctc ggtcacgacc tgcccgcctt
     3241 cggaccacgt ccgcatgctc tggaggttgt ccggccgcag ggacgccgcg atgcactccg
     3301 cccgggaatg ccgggtccgc aggatgcccc ggatctccat catgcagcca ccgatttctg
     3361 cagggcgtcc atgaaccggg agagctgccc tgcggggacc gttgctccag ctctctgcct
     3421 gtgaccgccc ccgaatccac cgacctggac tgccgcgacg tgcacgtgtt cgctgatatc
     3481 gatgtcgcgg cccggcgtga cgcggaccga gacgaaagcg aggtcatctt tctgcgctgc
     3541 aacggccaca acgggccggt catgcaggca gtcccgggag aaggcgtcgg caacgtcgct
     3601 tgcaaccgac gggtccccga cctccaccac gccggagacg tccttttgct cccagcacga
     3661 ccggagcgcc cggatcacgt tgagcctgtg cctgatcgtg cactcgtatg cctcgtcgag
     3721 acccgcggtt gaccggaggc agagggaggc agcaagcccc ccgtgtcctg atttcccgca
     3781 tgcgtccacg acagcggtga gcgtgtgggc gtccgggacg acctcccgct ggaggctgta
     3841 gcagtccccg tagagcgatt cgagcgtctt taccggagca tacggcgcca cccgcaggac
     3901 gatgagcgag aggagcttat cgagcgagac cttcccgtcc ccggctgcac tctccaggag
     3961 gtcggagact gccatctcgt cgccgctcac ctggtggaga taggggttga gcgccccgta
     4021 gagcctctcg tggtcgtccc tgccggcaag cagcaggcct ttgccggggg agaccaggcc
     4081 cagcgccacg gcatcgttga agatggcgag gttctctccc gccagttgct ggccgtcgcc
     4141 gatgatgccg agcatgacga gcccggcgag gtcgcggttg tcacccagcg cctgcgcaac
     4201 caggaacgcg gcccccgcgg aggagagttc gcgttccccg tcgacgccgc agagccgcgg
     4261 gttgacctgg agggcaccgc tgaaccgggg gacatggtgg tcgattacca tgacttccgg
     4321 cggcaggtcg gggatccctg atccgaggtc gcagaggagc gcaggcgtct ccggggagag
     4381 ggtcgcgggg ctgatgtgcg aaacgacgcg cagcctgaac cggataccct tccggaggag
     4441 tgccatgcag acgatggcac ctgctgctat tccgtccgca tcatggtgtg catacacctc
     4501 cacgaactcc tgccgggcaa tgtgcccggc gaggtgtgct gcggcctcgg ccagggtcat
     4561 gggatcttag cgcgagagca ggatctcggc actctccggc ttgtagctcc agtccttggg
     4621 cagcctgccc gtcccggtat agtacttgac caggcggcgg accttggact cggtgagctg
     4681 cagttgcctc ttgttgtgca ggtcgttctt gttctcggcc atgtgcttgc gaagaccgag
     4741 cgcctttgcg atcaggttcc gcaggtcttc cgggatctcg ggttccatcc ccttttcttt
     4801 caggatttgg ctgatccgtt ttcccgtcac cagtttcacg tcggggacgc cgtggcggtc
     4861 ccgcaggatc aggccgatcc ggctcgcgga catgccttcc ttccgcaggt cgacgatgat
     4921 cttctcgatg gccgcaacat ccgtgttcgc ccatgacggg gcttccttgc ggaacgggcg
     4981 gaccgatccc gagtgtcccc tgcgccgtgc gtgcattcgt gccatagtct tgtgtcacct
     5041 ccgaaatacc caaatgtaaa tccgaaaaga gccacaggct gactctccgt aatcccagga
     5101 ggcccgggtt acccgggccc gtgcatggtc tgcacgtcgg acttacatct gccagcaccc
     5161 ttataagtgc tgtctatcca tttggcaggc gtactcttaa tgatatcgcg ggggctacag
     5221 cggctgcccg tagcggttga tgagccggat caggtcggcg aatgcctcca tctccagggc
     5281 gagcaccgcg ttcctgtcca tgcccatgct cgtctcggcg tctgccgtga ggcactcggg
     5341 tccccgcagg atggtccttg caacaccgtc ccgcgagagg acggattggg cctccctgtc
     5401 gtacacgaat gccctgcccg ggatgatgac caggggctcg aggtcccggg ggtccagcgc
     5461 ccggaggtca tcgatggtga tcaggcaggc aatgtccttt tcgaccggga cgactgatgc
     5521 ccccttcccg cactgcgaga ggatggacgc gatgtaggga gcggcgatcc tgccggagat
     5581 gacgcttgcc cgcctcccga tacgggggag ttttgcgacc aggtccggtt ctgcggcgag
     5641 ggcaaacggt gacccgatct gggggtccca gaggggcgtc ccgctgatct ttatccggaa
     5701 cttccgggag agcgcggtga ccatgtcgcg gaacccggcg acatcctgca cggggtggcc
     5761 gggaatgacg ggggcgtttc cgaggatcag gccctggtcc gtccggttgg caaaccgcat
     5821 caggatgatg ccctttgcac ctctctcctc gagccagcgg cacgtctcct cgaggacggg
     5881 gccgtcgttg actcccggca ggacgacgca ggcagcgtac acgtcgatct cagcacacag
     5941 tctctcgagg accgcaagcg aggcttccgg tgtcgggtcg tgcatgtagc gcctccggag
     6001 atcggggcgg acggagaaga cagtgaacga tatctcggaa aggccggact ggacaaggaa
     6061 atctgcgatg ccgggatcat cgaacccctt gccgctcgtg tacccgatgt ggagcggggc
     6121 ctccatgctc gccaggagct cgatgagatc ccggaaacgg gggtaacagc tgggatcccc
     6181 gccgccgctg atcgtgatgc ggctcacctc gtcggggatg gcctggaggc gggcgaggac
     6241 atcatcggca acgtcgcgga ggtcccgaaa accgctgtaa gactcgcgga cgctccggct
     6301 gcagtagtcg catcccttcc ggaagggcgg gcagtaccgg cagccgaagg ggggcgtatc
     6361 ccggacgtgc ttgaagtaac agtactcgca gaacccccgg cagtcgacac cggggcgtcc
     6421 cccgatgtcc acggtgaggt gtgccattgt tccagtacct gtcttctttt ttttgcggtt
     6481 aatgcctttg gatggagact gtcgtcatgc acggacaacg gccgtgtcgt tgccctccca
     6541 cccgatgaaa agctccgaat agccaacggt cccccgtccc ccgtgggtta cccgttccgt
     6601 ctcgacgacg agccgcaccc tgacaggggg tttttccctc cccatgtcct gcggaggata
     6661 ggaccagtaa atcgatggtt ccacggtccg gacggtcgcg ttatggatga caaccctggg
     6721 atccgtcgaa ttccacgaga cgaagtggcc ataactcgca gtccacgtgt agatcaccgg
     6781 aatggttggg ctgaactccg gttcgaggcg gataccgaca gtggacgaca tgagcgggat
     6841 gtagcggtcg ggcgttgcac ggattgagat agcgaccggc gtgggtggga cggtcgatcc
     6901 tgctgtcatt gtttgcgttc ccggcaaaga cccggaggaa ccgccgtgag gctggctgca
     6961 ccccgaacag aggatgaggg cgaggaggaa taagcaggca gggaggaaac gtaccttcat
     7021 ggcacagagg ttcccgcccg gggacgataa aggagaccgt ttttccgtcc tcccgccggg
     7081 agggacgcat cgttccggca ggctgcgata cttccctcta tcccgtttca gtctcccggc
     7141 cggtgaatcc ccttgatcac gtggtactgc cggaccacta cggagaaagg tcatatcttg
     7201 cagggaagat ctgttgatag atcggcgctt gtgtccgtac cctgttatca cctgcctgtt
     7261 gacaccctgc ccgggtgcat cccctgcaat gcactccgga aaacctggat cattccctgc
     7321 catccactgc gggattaatg ggctctcgcg gatatctctt gggtatatga accgctcaat
     7381 ctattgcgga tgcctcctcc tctgtgcggc cctcgccctc ctcgctgcgg gctgccttgc
     7441 accggcggcc accgggcccg gcgcacacac tgcgcctttg cccgtgtacg cgcggggcga
     7501 cgtccttgcc gggaacatga cagcggccgg ctacgatacg cccgatccgg atattgcagg
     7561 agtgcgggcc ctcgtgctcg ggtttgagcc cgggagcgac atgtatgtct atacattcgt
     7621 aagaacgctc cccaacggga gctatggcta cgtcttttcc gagagctggg aagccaagct
     7681 tgcccgcccg cgaccggtct tcgaggcata cggccttggg aaggtcggga tgatggcaga
     7741 gaagtacctc tggaaagtct gaatgcgagt ggactgctgg gttgttcgaa cgcatggaat
     7801 cctgctattg atcccggaat atcccgggca aagccggagc cggaaccacg cccggggtaa
     7861 tcctttccca ttttttacca cgaatacgcg atgggggcct tgcggcccgg tgcagcacgg
     7921 gatgacaggt gacagcgtga tattgtgttc cggagggagg ggaactgccg acaggacggc
     7981 agcaggcctc cggggccggt atccactcat cccctcagga aaacagccat gatgcggagc
     8041 agggaagtcc tcctccagct cctccacgac tcccggtatt ccctttccga tgccgaggtc
     8101 tggtacattg accgcggtgc accagggaac acgagccggt tgtcgggcag ggacatcgtc
     8161 tccgtggagg cgttctcctt cggggtggca acggagaacg ggacaaaaga catcccttac
     8221 caccggatcc tccggattct ccacagggga gagacgctct gggagagggg gatgaagagg
     8281 gacaggagat gatgtgcggg gggaaacaca cccggggtgt ttcgcaaccg gcccttgttc
     8341 atgaaaacgc cggtgcattt ttgccaggag aatcgctggt tctttgcctt ctgggtgggt
     8401 gatgggaacc gaatgcgggg gctgacgcat gcagaggtca gagggtaaaa ggccgggagg
     8461 tcacaggaac gagaccaaaa gtgcatggac tgccccgcat ccactcccgc attgaggatg
     8521 gcccgggcag cccacccaaa aaccatcgcc ggcggttctc ctctccatgt catggaaagt
     8581 taaaaatcct cttttcatca accacctgga gaaaaagaaa cctgctggta aaccctcatg
     8641 caacgcatct ccttgacata acgaaaggta aaattcctct ggttcgtccg tctcccggag
     8701 aaggaccccg gtgcaaagtg ccggaacaac cccgaatgct catcctgctg cagggaacgg
     8761 acggctcgcc ttttattagt gactgcgagg cagggctccc ggacggtcat ccggaaggga
     8821 gaaaaagccc cggctgtcgc cacatttttc aggcaccggc tgcaacatta tatggcgccc
     8881 cagtggctta gctggcagag cggctgactt gtaatcagca ggtcccgtgt tcaaatcacg
     8941 gctggggctt ttgctctttg tgtccggttc tatatcgcaa tcattttgcc ttatttttta
     9001 ttttcatgaa ctgatctttc caagatacct ttgacgtcac ccctgtgtat tcttctgtcg
     9061 tatggacata gtatcagatc tcatgaaaca ggttgggaca ggagacaacc tttccctgat
     9121 cagcaggtca gttggtagcg atgaaaaggg tgtgcagtca gcactcggca tgggacttcc
     9181 ggtgatcatg ggtgctctgt caaactctgc acactaccag gcactgcgag tcactaggcg
     9241 tcagtggtta tacggaatac agcgacgaac acgctgcgaa ggagggtgcg aggagcggga
     9301 gagagcagca tgccggtgag gagtgaaaac gacgaaaccg ggagtgtcat cataccatga
     9361 tcaatcatga gagaatagga ccggtatgtg agcggagcag aatggaggag caccggacgg
     9421 gaggaggagc ggatggaatg gagcggagac gaacattccg ggccgtctaa agtgttccga
     9481 tcaattaaat gatatcgaga gcaaccagtt cctcaatttc ctcttgctct tcttcctttc
     9541 ttcgggaggt tttacgagaa aaagaagaag agttcgaagt gaacagactc ttcaaccaat
     9601 caagaaatcc caaagtcaag tcccggtgta ctggtaatca tctttcaatc accttcttca
     9661 cagaagtcct tgtaatcaca ccacttgcac gtctggtaat ctggccttgg ggagaactct
     9721 tctgcacata tcgacttgat cagatttacc acccgctctt caaatgtgcc tatggtctct
     9781 aatgttggag tgtagtcgta agtcttgtta ggtccaagat aatacagcga tgcttttacc
     9841 gggagcttcc cgtaaatctc gcgaatagca agactgtaga ggttcatctg tatgtcatcc
     9901 cggatggtgt tcttcgagag attccctggc ttggagcccg tcttgaaatc gatcaccacg
     9961 atttcgccgt caggcgtctc ttcaatacgg tcgataactc catttagacg tcttccccca
    10021 agagagatct ggaacctttt ctccgcttcg agaatacggt tcgggttgcc tgcctgccag
    10081 gtgaggtagg tatcaaggag agcctccgcc gtagcccggt ctttcatctc gtggctcttc
    10141 gattcgtacg cagcagtaga ccatgcggta tccagcaggg ccagggccat ctctttcgtg
    10201 ggcgcaatcc cctctctttg cttcttcgag agatgttcaa tgacggtatg aaccgcagat
    10261 cctaaatcga agaaggtccg ggaaagagac gggatctgga ggacatattg aaatttgtac
    10321 ttgagagggc aacgttcata ggtgctcagt ccggacgcag agaaggtatg ggattctcca
    10381 acgaggcagg gggtacgtcc ctgcatgagt gtctcgattt ctgcatcgtt ctccgtgaag
    10441 gtcaggaatg cattgcgatt gaatgatgag aggtcttttc cttctgatat aagccggatt
    10501 ttttcgaggg tgacaatgtg ctggagagcc gtctggagat gcaattgatg gatggctctc
    10561 tttgcctggt attggagggt ttgctgatat ttttccaggg ctgttttacc cctgagcgca
    10621 ggggcggata cgaccgcagg cacttctacc ttttggacaa gtgagggatc gtccagggga
    10681 agttcgtcca ggaattttga ctgcttggtg gggttcttgt tgttcccata ccactttgcc
    10741 ctcgtgagat agaggagatc ttcagcccgg gtcatggcaa cgtacagcag gcggcgttct
    10801 tcctgctcaa agagggcttt ctcgtcatgg gtggtcttca tccccttcga gaggtcattg
    10861 gggacaaaga actccttcgc ctggtactgg agcgggaacc ggttcacggc aaggtccgcc
    10921 acgaacacaa caggaaactc cttgcctttg ctcttgtgca cggtaaggac tttcacagaa
    10981 tctgcaacat cggtctcgcc cacctcgata gagaatcctg aaaggaatcg aaggtaggta
    11041 aggaagctat caactgttgc atccttggta atctcctcgt attcgcgggt tatggtcagg
    11101 aaatggttga ggaggaggat atcttgccct gtctcgtctt cgagggcccg ggcatacaga
    11161 tcggtggctt gcatcatgag gtggtggacc agggcggtga gtggcccccg gtctttctcc
    11221 atgatcaggg catccaaagt accgaggagc tcacggattg cggttgcatg gtgaggcgcg
    11281 agggagtcaa tgctccgcat cgcctcaaac acgccgtcgt tgtaggggtt gccgaaggtt
    11341 gctctccggg caaccgcgtt gatcttctgc acctcggtct ccggaattcc tgatattttc
    11401 atgacccggt tgagagggat tcctgcggtg aggggattgt tgatgatctt caggtatgcc
    11461 agcaggtcac ggattaccgg tgcggaaaaa aactccatct cacccacaaa ttctgcggga
    11521 ataccccggt cccggaggag ctggtagaac ttcgcaccat ccctcctcct ccgacagatg
    11581 atcgcgaaat ccttgtatgt atagggacgt tccaccttct cccggcggga caggaagcga
    11641 gtgccgagca atcgttcgat ctcgccgatt acatacgagg cctcggtggt ttcattctcg
    11701 cagtgtacca ccttgacagg ctctccggga ggattatcgg tgagcagctg tttctcccgc
    11761 cggttgggtg catgacgcat cagggccagc gccagagtaa gaatggtttg cgtgctccgg
    11821 tagttgtggg tgaggaggat cacctgtgcg tcccggaagt gctggagaaa atcctgcatg
    11881 ttcgtgaggt acgcgccccg gaaccggtag atggtctggt catcgtcgcc gaccacgcag
    11941 aggtggtccc cggcaagcat cttgatcagc tgcaattgtg cataattcgt atcctgaaat
    12001 tcgtccacca gtatgtgggt gaaccgctcc cggtatctcc ggaggatgag aggttttcgt
    12061 tcgaacagcc ggcaggtctc atggatcatg tcatcgtaat cgaggagcat ctcttctcgt
    12121 ttgaagcgtt cgtaggcccg gtagaccttg atgagatccg agagtttttc gaggtatgcg
    12181 gattcttctg cggaaacggt gacattttct ttctttttga gatagtgggc aagttcatcc
    12241 ggtgaaatta gttcgtcccg gaatgcactg ataccatcaa ttattgcttc aataacgtca
    12301 acggcattgt tccccacttc gatatgctca aacccgaacg agtcgatgtt cttcagtccc
    12361 cagacgagtt ggttcgcccg gctgataacg ccggaactga aattgatacc tgaatctagc
    12421 cgattctctt ccaataccga gaggcagaat gagtggaatg tgctgacagt gagatcggca
    12481 ctctgaggta cggagtccaa acggtcccgc atctcttggg cggctttgtc tgaaaaggtg
    12541 agggccagga tatttgacgg aggcaccccc attgagatga ggtaacggat cttttcagtg
    12601 atgacccgtg tctttcctga cccgggaccg gcgaggatta gctggatgcc ctgacgggta
    12661 acggcatcga gttgggcggg attgagatgc atataacact attagatggg atccggaaaa
    12721 atgtgatgaa aaagccataa tggggaataa tctttgcaat ctaacactat ctcttggatt
    12781 tatctccgta tctcgacccc gacctcattt cttcgcagga atccgggggt gaacggcgaa
    12841 ttgtaccgca tgaggaacgg cgttcccacg ggggaaatat ttgcccttgc aagggatgcg
    12901 aggagccgtt cgcgaacgag agagacatcg cggtccgaag cacttccccg gaaccggatg
    12961 actgcaagtt cccgtgaggg gacttcctgg atgctgaccc gcatgtcgag gggctctgga
    13021 atatcgtttc ttgtataggt cgcgggcatg acgaatgaca tcgaatgtgc atcggacagg
    13081 acgggcgccg tcatggcaat cttttcgggg gtgatgaccg gtgcggtcat gggcaccttt
    13141 ttccctgact ggttatttcc cgagatgaag cgaaagagta tcgtgaatgc ctcgttttca
    13201 tcggttcctg aaacggttgc gagaatgagg ggtggatacg tgcggaattc gatatctccc
    13261 aggtgcccgg ttacttcgta agcgatggtc ttggtcatgg cctctcgttc atggcatggg
    13321 acctttgggg taaaagagtg atggttaggg aaatacccag ggaatgaaaa ggcagcctga
    13381 tgggaccttc gaggaaggaa ccgtcaatga cctggtggac aagcgcctga aagagatggc
    13441 agacaccctg aaggaatatt atccggctcc ctgatcagga aacctcaggg aaggtcaggg
    13501 aaaggacacc agcccggggc attccccgga ggctgtcctc attttttccc gtaggggcag
    13561 gcatacaggc acagcccgca gaccgcaacg ccctttttcc cttccatttc cctgaagtac
    13621 tggtcgcatg cagccgcatc gaggcgtgcc tcccgcggct cggacggatc gaacatcctg
    13681 cccgtgattg cccctttcgg acaggtatcg gcgcatgccg tgcaagtccc gcaatggggt
    13741 tccatggggg tcccggtcac gccgagtggt gcatcggtaa gcacgctcac ccaccggaca
    13801 cgggggccgt tgtccggggt gacgaggagg cagctcttcc ctatccaccc caggcctgca
    13861 aggtgtgcag caagcttgtg ggagaagacc gaccggatct cccggtcatc tgtgcgtctc
    13921 gatgcgggaa ccggaaatgc atggtatccc gcacgctgga gttcgcgagc cacccggacc
    13981 gagacctggt cgagcgcctg gttgaggacc tcgtagccgc tgtgccggta gatgactgca
    14041 gcctctgcat cgccgtcggg gacgagctcc acgatgtcat cgggtatctg catgccgatg
    14101 gaaatggccc gcgggtaacg ggcgatccgc tctccaccct ggcggagaat gaaatcgcgg
    14161 gcgggagcaa ggtcggccac cccgtagtaa ccggcaccga gcgaatatgc aagggagtgg
    14221 attcgatccc cgagtgcgaa agacatggtg aatgagtggt gtgccgggat gcgacttgtc
    14281 attatcggca ggaatgccca tcccgtgccg gggatgacgc aggacgcgtt cccgctctcc
    14341 tctcccgatt cgcttaaata ccctggtctc ccactgtccc ctgaagatgg aaagaggttt
    14401 tttgcagatg aacacacggg acatcataaa aaggctttgg gacgaggcag gacgggggaa
    14461 ccttgcgatc tgggatgacg agaccatcac ggtggtcccg caggactacc cgggcgaaac
    14521 cggtgggaaa agaccggtcg cgatcctcaa accccttctc ctcgtgaaca agtacgattt
    14581 cctcgacttt gcactcgcgg acgaagaact cctcaccacc attgaggaag ccatacgggc
    14641 aggcgggggc agggtcacga gggactagca ccggtcccgc ttcattgcct ctgccttcag
    14701 ggcggctggc atcaacccga ttgcgtaccg gagtgcggtt cccggcattt tatccctgtt
    14761 ctccatgaca aacgagaata tctcgccgac atgtttcctg cttgcctcct tgaggagcca
    14821 cccgtacccc cttctgcacc atgtcgtcgc cgtcggtcag gaggagtgtc gcaatcaata
    14881 tcgattcgtc gaggaatttt ccgtgctttg ccggtaagat gagcgacacg gctgctgccc
    14941 tccgcagcca gcggttttct gatcgtgtcc actgttcgag ttcgctgata gaatccggga
    15001 accgcccgat gaaatcacca gccgcgtggt tgcagaaacc gtcgcaggac gcccagttgg
    15061 tgatataggc ctcgatccag tgtcggaaga ccgcactatc ctcccggtca tagcgcaggg
    15121 aaaggcggcg tgcccattcc gaagcgatga aggactcctc caggtagccg gaccggtaca
    15181 gctcctcgca aagagagagg atttccttct tgtcccgcga ccggatcgtt gcccagtact
    15241 ttttcgcgat tgtggtggcg gtagtggtct tcatgccata gcatgtgacc ggttccctga
    15301 agaaccgccg ggaactcttc cggatcccgg ggtcggcgtg tttttcaagt tcctcccgga
    15361 taagagagat gaccgggtcc atgcagggag caggtgcggg ggagaagaat atggg
//
LOCUS       DAOOJU010000036        14332 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_4031_length_14332_cov_14.932479, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000036 DAOOJU010000000
VERSION     DAOOJU010000036.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 14332)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14332)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14332
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4031_length_14332_cov_14.932479"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1500
                     /locus_tag="PK679_08020"
     CDS             <1..1500
                     /locus_tag="PK679_08020"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC55935.1"
                     /translation="APAAKNLGDTLVALQLWGEALRAYDQALAMDPALASAAVARGDL
                     LSRFGRNGEALSSYDQALGIDPDSTSVLSKKAQVLAALGRTEEALSTIDRILVLEPGN
                     ATYWVHKSFLLNNLGRFNESLDASGTAISLEPNNAVAWNNRGFSYNSLGMFGDAVSAY
                     SQAIAIDPGNPAAYTNRGFALLNLGKGEDALGDLDRATTLQPDLATAWSYRALADYRL
                     GRFTEALDDASRATRLNPKDSLAWSTGGMALLQKGEFRKAIPYFDKALTLNPNASDIW
                     LNKGIALYMAKNNEEALSALDRVLELDPESMTAWQYKVYALRALGRGEEAVWITDRQL
                     KTDSWNTTLLLRKATALVILNRMGEAQLALSRILEKDPSNYEALVARGKIQIASGDYL
                     GAIRTFDVLQKTMPDADESLIFLGVAYYRSGQYEKALAVYDKLLKKDPANSLTWSNRG
                     YALIKTGRIQDAIKSFDRALELDPNNMDAQYGKFEAIRIMWPSYVPDGI"
     gene            complement(1503..2360)
                     /gene="thiL"
                     /locus_tag="PK679_08025"
     CDS             complement(1503..2360)
                     /gene="thiL"
                     /locus_tag="PK679_08025"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HPC55936.1"
                     /translation="MDERALKRVVASVVGKDAVLDDCAVLALGDTFLVATTDMLHEST
                     DFPEWMTDREIGWMSAAVTLSDIAAMGARPSLVLLAAGLDSPSRLEEILTGARDCCST
                     CGATLAGGDLDAHRELTLVSSGIGFAERPVRRSGARPGDLVGIVGIPGRAQAALEGYS
                     RFREYLSTPKPRIGEGLALAAAGASSMMDISDGLLASLEDMRQASGLGYAIESEKIPG
                     LPGVPDDVALRFALLGGGDYGLLFTIPPEKRIPDLPEIFVIGRVIEKSQIIVDGRPVE
                     GTGYQHHWD"
     gene            complement(2353..4308)
                     /locus_tag="PK679_08030"
     CDS             complement(2353..4308)
                     /locus_tag="PK679_08030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF460 domain-containing protein"
                     /protein_id="HPC55937.1"
                     /translation="MKVFGIDVITGSVRSRSRRPRYALVILSGTKITEETEVTGFRLL
                     RRLAEEKPDILAVDSLQEVAQDTHDLYAFLQMLPPSVRLVQVTGGEKKETLGKVASRY
                     NISFNRFDPFDEARTIARVASLGAGSEVIAFENESEIVVSRHRSPGKGGWSQNRYCRK
                     IHGAVLQKAREIEMALLAAGVKYEKRETRAFGGCSRVSFSVQAQREEIPVSAYRGADV
                     QVRIHGKRLDRIRFRPLTGKPRYLIVGIDPGTTTAVAALDLDGNLMHMESSRQLSMAG
                     VIETLYRVGKPLIIASDVHEMPYSVEKIRRAFNGVAYTPKADMSVEAKHALTQDYDPR
                     NDHERDALAAAIDAYRAYRNKFQNLVRRIPPGYDIDEVRAGIVRGQSLEQVIGEMTEK
                     ATPAGEEEAPDVRIDAARDEKVRVLDGTIKRLRALVAELQEEIHRKDERIARLETRLK
                     KVRSRQDQRIRSDAEITKRDVIIANLRKRLRSEEKTTKQLRRRIMKMREFDEALLSGE
                     TVPLKILSALTKEGVRALSAEMGIREGDVLYINRIEGFGKVALRELAEARIGALLVEE
                     NQNESAFHEIEEFFRESGIAVLSTRSVRAVVKGNRGAADPAEFRSAMREWKESQERYE
                     REKKGQLVLQIFEEYRTERGREMRKVG"
     gene            complement(4305..5162)
                     /locus_tag="PK679_08035"
     CDS             complement(4305..5162)
                     /locus_tag="PK679_08035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIO1 family regulatory kinase/ATPase"
                     /protein_id="HPC55938.1"
                     /translation="MAISAETIRQLHPYETRILHTLERLMGSHSWVPLDLIRKRAGFS
                     ESETLFRLGTLMEKGMVRYDVVPYEGYSLTFLGADTLALLSLSRHDTLSALGPLVGEG
                     KESVVYEGLGLGRVAVKCHHVGQRSFQSVRLSREYIAEKTHCPWIFASRASAEREYEA
                     LKRLHPGARVPLPVGRNRNVIVMEFIEGTTLNRTRPADPAGVLAAILEQVAIAYSLGV
                     IHADLSEFNVMLDRKGVVLIDWPQWVTPDHPNAGQILARDVENILRYFNRKFGIVADS
                     TEEIARVTG"
     gene            5183..6109
                     /locus_tag="PK679_08040"
     CDS             5183..6109
                     /locus_tag="PK679_08040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00269 family protein"
                     /protein_id="HPC55939.1"
                     /translation="MLMIKVDLITSMRCDKCRRPAVLFQRYSGLHLCREHFFADFEAK
                     AKRTIRENRWVSRGDTIAVAFSGGKDSGALLFFLHSLLSRRKDVSLVAITVDEGIPGY
                     RDPSRAGARARELDIPHMTVSFREAYGITVDEIVERKGGALSCTYCGVLRRHLLNAAA
                     RDAGATKLAFGFNLDDEAQTVLMNVLRGDTARLLRGAHPVPGMVPRIKPFLSIPEREV
                     ALYSFLRCGTVDTGRCPYSQNAMRAEVRQMLNAYAWNHPSARFALVNLGRELAELGAG
                     RTGELQVCSRCGEPCGTTCRSCGILDEVRHGA"
     gene            6099..7823
                     /locus_tag="PK679_08045"
     CDS             6099..7823
                     /locus_tag="PK679_08045"
                     /inference="COORDINATES: protein motif:HMM:NF014325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HPC55940.1"
                     /translation="MVRDRKVTLWRLLHGSRRVKAVIYFLIFGAQIALYTLLFHYAYP
                     LLEGKPITWPASLLFVLETITTVGYGDLLPFTNQYTVLIVILMMVSGIIQIFMVIPLL
                     LIPTIGSHLQPSPPQRISHEISGHVVIVGHNPITKALVESLLISELPVVIIVDQKETA
                     FMLSDLFGKRVYVIWGSYHDNETWEGAWVEKARHVVVCEEEQTTASIIIGMRAMTKAR
                     IIAVVDKLSFERYLRYAGADSVLSPKHVTGQILARHVALTSHVDTLVEETVVDENGIR
                     VTPRAGDPLRIINIPVLAGSPAAGHRLGELELSPRFGAECLLISRRGQFSFFPGPDEV
                     LDTSTMLFLLTWMSSVEKLVADLFLPPGETRFLGVVTGFGDVGRSAYRELTALGMECV
                     VVDQKPYPVNIVVGNAEDEDTLLEARIRDADFCIVALNDDSRNILTTLMVRNLNPRTR
                     ILARANDAASVDKLARAGADYVALLPSIGGQIVAGVLLADTVYIILSLPNGQVIVRGR
                     YSTGIPATVSSIEKSCAVRILGIQGKEKSIIYPDGESAVHAGDILLVMGFPRGLRKFI
                     RVTQRDLL"
     gene            7829..8569
                     /locus_tag="PK679_08050"
     CDS             7829..8569
                     /locus_tag="PK679_08050"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD+ synthase"
                     /protein_id="HPC55941.1"
                     /translation="MDEEAGCALGRIEQLLRYVYWKSGSRGYVIGVSGGIDSAVAATM
                     CCRAVGPERVLGLIMPSGVSEPSDISDAGEVCQRLSMDFRTISIEPVLSAYRSVPGFQ
                     DDRTLLGNLMARTRMAILYYHANRLGMLVCGTSNRTEYMIGYCTKWGDNAADVQPILH
                     LYKTEVYELAATMENIPERVLRKVPSAGLWKGQSDEAEIGLSYPEIDAALKSLEQNGW
                     TSQNPVEDRVLSMVRASEHKRRPAPSLL"
     gene            complement(8564..9259)
                     /locus_tag="PK679_08055"
     CDS             complement(8564..9259)
                     /locus_tag="PK679_08055"
                     /inference="COORDINATES: protein motif:HMM:NF018288.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase family protein"
                     /protein_id="HPC55942.1"
                     /translation="MEDWKKYAGSPVTRSVEDLRPVLRNPACDLDGPAYLMFRDIARS
                     PVDRAWLSERHLRYDVTCIPPRDLCGEFVKTKGHYHPDNPSGMGYPEVYQVLSGRAHF
                     LLQRRDLGRIVLVPAGEGETVLVPPGYGHVTINPGEGDLVMANIVSSCFESDYRFYEE
                     NRGAAYYELVSGELEKNPRYPSVPPAETRQPHEITPGPWRDGSLYGYVERRDEILCAL
                     VYPERYMHTLSIL"
     gene            complement(9259..10536)
                     /locus_tag="PK679_08060"
     CDS             complement(9259..10536)
                     /locus_tag="PK679_08060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="COG1361 S-layer family protein"
                     /protein_id="HPC55943.1"
                     /translation="MNLRRIVFLAVLISLLCVPALAGVKYLAGEPDLSAAIQGRNEFS
                     PGEDVTLRVTIENRGLVDMKFVQSGIIEREDLPNTAKLVKATLGAGDSPFIIKADPQV
                     VGDIPGGKSATVSFAAKIPSDAPSGNYTLPLHVRYSYLKTAEQYGQDAISYTYRDVEE
                     TIPLMVRVQPRAMLEVIAMSGEALNAGTEGYLSLSVRNKGYEDARDTVVYLSRNGNSP
                     IVPTDSNIYIGEFPAGSTRDVRFRVSVSRQASEGSYPVDIFCKYTNNEGDTVTSDTVT
                     VGVPVSGKISFAVVSPPAEARAGGKTVIKVVYENTGSATARDAQARISAVDPFSSNDD
                     SAYLGDIAPGERAVALYEVNVDAGAVLKEYGLDSEIRYRDALDNSVISDTMKVRVKVV
                     SPGISPLAIAGIFVLVALAAGAVYYIRKNQKKG"
     gene            10601..11374
                     /locus_tag="PK679_08065"
     CDS             10601..11374
                     /locus_tag="PK679_08065"
                     /inference="COORDINATES: protein motif:HMM:NF014080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC55944.1"
                     /translation="MAETPSPYLALTEILKSLGLTKYEALVYIGLLKEPGATATRIHE
                     VAGVPRASVYPVLGRLIQKNMVSVSLATPRRFEAVPPDAAIDHLLDAVSADAVRAKKM
                     LAKIWRERNQKAPADQDYIWSIYGIENIRARLADLLRNATVSIDAVLFGDLPEDICSV
                     LCEKAASLPVKVTTRNPEKFACRGIEVSLLPPLPKDVLDVDTRFTGGFFLIDEERAMV
                     VIVTGTEEGTALFSESRGFIRFFLSYRDLVSSLVKKIGQ"
     gene            complement(11368..12114)
                     /locus_tag="PK679_08070"
     CDS             complement(11368..12114)
                     /locus_tag="PK679_08070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF128 domain-containing protein"
                     /protein_id="HPC55945.1"
                     /translation="MHLPLKFVHTRIEEYAMQVTYDPREGGGLVVYNLSFVQNGDLDA
                     AITVMRDTFRAGLCVSGLVRFVGEGGTAGETKVPAGHTGIITICSSTLDGILLRRGIP
                     SNPIGGGVVEIEGRIPRRFIHLILYEHTTIDPLQALLSQEITSVTGMMRRGSGNILAN
                     IRQCHMEAEGQIGEVIDDLAGSSFSPILDVGLPNTPALGVTVDPQYMGIVALGGTNPM
                     AAIKERGIAVTTHAIKGLMDVRDLEEILDY"
     gene            12178..13146
                     /locus_tag="PK679_08075"
     CDS             12178..13146
                     /locus_tag="PK679_08075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55946.1"
                     /translation="MDEKVREKARNAIKTILEAAGYEVDTLKDPYDLASRDNDYIMVL
                     CSDDEDEIADFANGNFRLMSGGEEITYRKLLFSLNPGAGAEGCTVWGRDEFVRLYGEA
                     ALAGILSRPFSLAIGAGERGGTAPSVPSPAERGTGEGEEEASGVIIPHLPIRVKKDAA
                     VQIAKMQGTVALKFMPFWFYSYRSSGEQVYKEHRVPFDAEGDGGLNAINGLKFEVDAK
                     SLVEDAVPAGAEVVSPRITQEEAREKIASEVAENLTQRIRIKQVSGDAISYEEKVLKP
                     DRRNIEVTVRQVYVPIWQVRGKKIVEVNAFSGEVLSSPMDEGVEIF"
     gene            13158..>14332
                     /locus_tag="PK679_08080"
     CDS             13158..>14332
                     /locus_tag="PK679_08080"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC55947.1"
                     /translation="MIGVLGGGPAGRTAAMKLGLAGKDVTLVEKGGLGGQCLHYGCMV
                     VCALNDVARTLHTARNLHALGILDRVPSFSFPRTISQMVSVQEKITAILDAETRGCGV
                     AIVRGEGSVEGNSLSVGGKALQTSALVIATGSLPRIPSIPGVQNPGVFHAHSLSSMLA
                     VPDRLLIIGGGIMAAEFAFIFHEWGADVDIAVRSTFLREVPRVLREAAKKDLEGIAIH
                     ENCTVTRIDGDPAVRSAILQCREGEKEIPCDAVFLAAGLVPNSRMVSGIRKGDDGRII
                     VDRRMATSVPGVYACGDVTGSPCLTPVARQEGIVAASSILGEDVLMDYSAIPQSVALA
                     HEYAFVDGEPADNEVAFSSPGPAGPGTFWEVPRGRTGMAELIVSRQDGRIGGISVAGP
                     "
BASE COUNT         2774 a         4421 c         4247 g         2890 t
ORIGIN      
        1 gcaccggcag caaagaacct cggtgacacc ctcgtcgcac tccagttgtg gggcgaagcc
       61 ctccgtgcct acgaccaggc gcttgcaatg gatcccgctc ttgcaagtgc cgctgttgcc
      121 cggggagacc tcctctcccg gttcgggaga aacggggagg ccctctcgtc gtatgatcag
      181 gctctcggga tcgaccccga cagcacctcc gtgctctcga aaaaagccca ggtgcttgcc
      241 gcactggggc ggacggagga ggcactgtcc accatcgaca ggatactggt cctggaaccc
      301 ggcaatgcca cgtactgggt ccacaaaagc ttcctcctga ataacctcgg tcgcttcaac
      361 gaatcgctcg atgcatccgg cactgcaatc agtcttgagc caaacaatgc agttgcatgg
      421 aacaacaggg gcttttccta caattccctg gggatgttcg gggatgccgt ctctgcatac
      481 tcccaggcaa tcgcaatcga tcccgggaac cctgccgcat ataccaacag gggttttgca
      541 ctcctcaacc ttggaaaagg agaagacgca ctcggtgatc tcgatcgtgc taccaccctt
      601 cagcctgacc ttgccactgc ctggtcgtac agggcccttg ccgattaccg gctcggccgg
      661 ttcaccgagg cccttgatga tgccagcagg gcaacaagac tgaatcccaa ggattcgtta
      721 gcatggtcaa cagggggcat ggctctcctc cagaagggag agttccggaa agccatcccc
      781 tacttcgaca aggccctcac gctcaacccg aatgcatcgg acatctggct gaacaaggga
      841 atagccctct atatggcaaa gaacaatgaa gaggccttat cggccctcga ccgggtcctc
      901 gaactcgacc cggagagcat gacagcctgg cagtacaagg tctatgcgct cagggccctc
      961 gggagggggg aggaggcagt ctggataacg gaccgtcagc tgaagacaga ttcatggaat
     1021 acaacgctcc tcctccggaa agccaccgca ctcgtcatcc tgaaccgcat gggtgaggcc
     1081 cagctcgccc tttcccgaat cctcgaaaaa gatccttcca attacgaagc gctcgtggca
     1141 aggggcaaga tccagatcgc ttccggtgac taccttggag cgatcaggac cttcgatgtt
     1201 ctccagaaaa caatgcctga tgccgatgaa tccctcatct tcctcggtgt cgcatactac
     1261 aggtccggcc agtatgaaaa ggcccttgcc gtttacgaca agctcctgaa gaaagaccct
     1321 gccaactccc tgacctggtc caacagggga tatgccctca ttaaaaccgg caggatccag
     1381 gacgcgatca agtccttcga tcgtgccctt gaactggatc cgaataacat ggacgcacaa
     1441 tacgggaagt tcgaagccat ccggatcatg tggccgtcct acgtcccgga cgggatctga
     1501 atttagtccc agtggtgctg gtaccctgtc ccttcgacgg gcctgccgtc aacgatgatt
     1561 tgggattttt caatgacgcg cccgatgaca aaaatctcgg gcaggtcggg gatgcgcttt
     1621 tccggcggga tggtgaagag gagtccatag tcccctccgc caaggagtgc gaaccggagc
     1681 gcaacatcgt ccgggactcc cggtaacccg ggtatctttt ccgactcgat tgcatatcca
     1741 agcccgctcg cctgtcgcat gtcttcgagg gaggcaagca gcccgtcact tatatccatc
     1801 atggacgagg cgcctgcagc ggcaagggcg agaccttccc cgatccgggg cttcggggtg
     1861 ctcaggtatt cccggaacct gctgtacccc tcgagcgccg cctgtgcccg tccgggaatc
     1921 ccgacgattc ccaccaggtc accgggccgg gcacctgacc tccggacagg acgctctgca
     1981 aacccgatgc ccgagctgac gagcgtcagt tccctgtgag cgtcgagatc gccccccgcg
     2041 agcgtcgcac cgcaggtaga gcagcaatcc cgggccccgg tgaggatctc ttcgaggcgg
     2101 gaaggggagt cgagcccggc ggcgaggagg acgagggaag ggcgggcacc catcgctgcg
     2161 atgtcagaga gcgtgactgc agcactcatc cacccgatct ccctgtccgt catccattcc
     2221 gggaaatccg tgctctcgtg gagcatatcg gttgtcgcga ccaggaacgt gtccccgagg
     2281 gcaaggactg cgcagtcgtc gaggaccgca tccttcccga ccaccgaggc aacaacacgt
     2341 tttaacgcgc gttcatccaa ctttcctcat ctccctgccc cgctctgtcc ggtattcctc
     2401 gaatatctgc agtacgagct gtcccttctt ctcccgttcg tacctctcct gcgactcctt
     2461 ccactcgcgc atcgccgacc ggaactcggc cgggtccgca gccccccggt tccctttcac
     2521 gactgcacga acggagcgtg tcgagaggac ggctatcccg gactcccgga aaaattcctc
     2581 gatctcgtgg aatgcagact cgttctggtt ttcctcgacg aggagcgccc cgatccgggc
     2641 ttctgccagt tcccggaggg ccaccttccc gaaaccctct atcctgttga tgtagaggac
     2701 atctccctcg cggattccca tctccgcgga gagtgccctg accccttcct tcgtgagggc
     2761 agagaggatc ttcaggggga ccgtctctcc cgagaggaga gcctcgtcga actcccgcat
     2821 cttcatgatc ctcctgcgga gctgctttgt cgttttctcc tcgctgcgga gacgttttcg
     2881 caggttcgcg atgatgacat ccctcttcgt gatctcggca tcagaccgta tccgctggtc
     2941 ctggcgggat ctcaccttct ttaagcgggt ctcaagcctt gcaatccgct cgtccttcct
     3001 gtggatctcc tcctggagct cggcaacgag tgcccggagc ctctttatcg tcccgtcgag
     3061 gacgcgtacc ttctcgtccc gtgcagcatc gatcctgacg tccggtgcct cttcctcccc
     3121 ggcgggggtt gccttctcgg tcatctcccc gatgacctgc tcgagagact gtccccggac
     3181 gatgccggcc ctcacctcgt cgatgtcata gcccggcggg atcctcctga caaggttctg
     3241 gaacttgttc ctgtacgccc ggtacgcgtc gatggccgcg gcaagggcat ccctctcgtg
     3301 gtcgttccgg ggatcatagt cctgcgtgag tgcatgcttg gcctcgacgc tcatgtcagc
     3361 cttcggcgtg taggcgacgc cgttgaaggc ccgccggatc ttctccacgg aatagggcat
     3421 ctcgtggacg tcagaggcaa taatgagggg ttttccgacc cggtacaggg tctcgatcac
     3481 cccggccatg gacaactggc gggaactctc catgtgcatg aggttcccgt cgagatcgag
     3541 cgctgccaca gccgtggtcg tgcccggatc gatccccacg atgaggtacc gcggcttccc
     3601 ggtgaggggg cggaaccgga tccggtcgag ccttttgccg tggatcctga cctggacgtc
     3661 tgcaccgcgg tacgccgaga ccgggatctc ctctctttgt gcctggaccg agaaagagac
     3721 cctgctgcag cctccaaatg ccctggtctc cctcttctcg tatttcacgc ccgcagcaag
     3781 gagtgccatc tcgatctccc tggctttctg gaggacagcc ccgtggatct tcctgcagta
     3841 ccggttctgg ctccacccgc ccttgcccgg ggacctgtgc ctgctgacaa cgatctcgct
     3901 ctcgttctca aacgcaatga cttccgaccc ggctccgagt gatgcaaccc gggcgatcgt
     3961 ccgggcctcg tcgaacgggt cgaacctgtt gaagctgata ttgtagcggc tggcgacctt
     4021 cccgagcgtc tccttcttct cgccccccgt cacctggacg agccggacgg agggggggag
     4081 catctggagg aacgcgtaga gatcgtgcgt gtcctgcgcg acttcctgca ggctgtcgac
     4141 ggcaaggata tcgggctttt cctctgcaag cctccggagg aggcggaatc ccgtgacctc
     4201 cgtctcctct gttatctttg tcccggagag gatcacaagg gcataccgtg gccgccgtga
     4261 ccgcgaccgc accgatcccg tgatcacgtc gattccaaag accttcatcc cgtcaccctc
     4321 gcgatctcct cggtgctgtc tgccacgata ccgaacttgc ggttaaagta acggagaata
     4381 ttctccacgt cacgggcaag tatctgcccg gcattggggt ggtcgggcgt gacccactgc
     4441 ggccagtcga tcaggacgac tccctttctg tcgagcatca cgttgaactc ggaaaggtcg
     4501 gcatggatca cgccgagcga gtacgcgatc gcgacctgct cgaggatggc agccaggacg
     4561 ccggcagggt ctgccggtct cgtccggttg agcgtcgtcc cttcgatgaa ctccatcacg
     4621 atgacgttgc ggttccggcc aacgggcaga gggaccctgg ctccgggatg cagccttttg
     4681 agagcctcgt attccctctc tgcggatgcc ctcgatgcaa agatccatgg gcagtgcgtc
     4741 ttttcagcaa tgtactcccg cgagagccgc accgactgga acgaccgctg acccacgtgg
     4801 tggcacttga ctgccacgcg gccaaggccc agcccctcgt atacgaccga ttccttgccc
     4861 tccccgacga gggggccgag tgcagagagg gtatcatggc gggacaggga aaggagcgcg
     4921 agggtatcgg cacccaggaa tgtcaggctg tacccttcgt aaggcaccac gtcataccgg
     4981 accatcccct tctccatgag ggtgcccagg cggaacagcg tctccgattc ggaaaagccc
     5041 gcccttttcc tgatgaggtc gaggggaacc catgaatggg aacccatcag ccgttccagg
     5101 gtgtgcagaa tccgggtctc gtagggatgg agctgccgta tcgtctcggc agaaatggcc
     5161 atgtctgcta cacaatttat ctatgctgat gataaaggtt gatctgataa cctctatgcg
     5221 ctgcgacaaa tgcaggcgtc ctgctgttct atttcagcgt tattcaggtc tccacctctg
     5281 ccgggaacac ttctttgcgg acttcgaggc aaaggcaaag agaacaatcc gggaaaacag
     5341 gtgggtctcg cggggtgaca cgatcgccgt ggcattctcg ggcggaaagg actcgggagc
     5401 actcctcttt ttcctccatt cgctcctctc gcgccggaaa gacgtatcgc tcgttgccat
     5461 cacggtggac gaggggatcc ctgggtaccg ggacccgtcc cgtgccgggg ccagggcccg
     5521 tgaactggat atcccgcaca tgaccgtttc gttccgggag gcttacggga taacggtcga
     5581 cgagatcgtg gagaggaagg gcggtgcact ctcctgcacg tactgcggtg ttctccggag
     5641 gcacctgctc aatgccgctg ccagggacgc gggtgcaacg aaacttgcct ttggcttcaa
     5701 cctcgacgac gaggcccaga cggtcctcat gaacgtgctg cggggggata ccgcacgtct
     5761 tctcaggggg gcgcaccccg tacccggaat ggtcccgcgg atcaagcctt tcctttcaat
     5821 cccggaacgc gaggttgcac tctactcctt cctccggtgc ggaacggtgg acacggggcg
     5881 atgcccctat tcgcagaacg cgatgcgtgc agaggtgcgg cagatgctca atgcatatgc
     5941 gtggaaccac ccgtctgccc ggttcgccct cgtgaacctc ggcagggaac tggcagaact
     6001 cggtgcaggc cggacggggg aactgcaggt gtgttcccgg tgcggggagc cctgcgggac
     6061 gacctgccgg agctgcggga tactcgacga ggtgagacat ggtgcgtgac cggaaagtaa
     6121 ccctgtggag gctcctccac gggtcccgga gggtgaaagc cgtcatctac ttcctcattt
     6181 tcggggccca gatcgcttta tacaccctgc tcttccacta tgcctacccc ctgctcgagg
     6241 gaaaacccat cacgtggccg gcatcactcc tctttgttct cgagacgatc acgacggtag
     6301 gctacgggga tctcctcccc ttcacgaacc agtacaccgt cctgatcgtg atcctcatga
     6361 tggtctcggg gatcatccag atcttcatgg tcatccccct cctcctcatc cccaccatcg
     6421 ggtcccacct ccagccctcg cccccgcagc gtatctccca tgaaatctcg ggacacgtcg
     6481 tcatcgtcgg tcataacccc atcacgaagg cgctcgtcga aagcctgctc atctcggagc
     6541 tcccggtcgt gatcatcgtg gaccagaagg agacagcctt tatgctctcg gacctctttg
     6601 gaaagcgcgt ttacgtgatc tggggcagtt accacgacaa tgaaacatgg gaaggtgcat
     6661 gggtggaaaa ggcccggcat gttgtggtat gcgaggagga gcagaccacg gcaagcatca
     6721 tcatcgggat gagggcaatg acaaaagcac ggatcatcgc ggtcgttgac aagctctctt
     6781 ttgagcgtta cctgcggtac gcgggggcgg atagcgtgct ttcacccaag cacgtgaccg
     6841 gccagatcct cgcccggcac gtggcactca cctcgcatgt cgatacgctg gttgaagaga
     6901 ccgttgtcga tgaaaacggc atccgggtga caccccgggc gggagacccc ctccgcatca
     6961 tcaacatccc ggttcttgcg ggatctccgg cagcagggca ccggctgggt gaactggaac
     7021 tctccccgcg gttcggcgcg gaatgccttc tcatctcgcg caggggccag ttttcctttt
     7081 tccccggtcc cgacgaggtg ctagacacct cgacaatgct cttcctcctg acatggatga
     7141 gctctgtcga gaaactggtt gccgatctct tcctcccacc cggcgagacc agatttctcg
     7201 gtgtggttac cgggtttggc gacgtggggc gatcggcata ccgcgaactg acggcccttg
     7261 ggatggagtg cgtggtggtt gaccagaaac cctaccccgt caatatcgtg gtcggaaatg
     7321 ccgaggacga ggataccctt ctcgaggcga ggatccggga cgcggacttc tgcatcgttg
     7381 ccttaaacga tgactcccgc aacattctca ccactctcat ggtccggaac ctaaaccccc
     7441 ggacccggat cctcgcccgc gcaaacgatg ctgcgtccgt ggataagctg gcacgggcag
     7501 gtgccgatta cgtcgccctc ctcccgagca tcggcggcca gatcgtcgcc ggtgtcctcc
     7561 tcgcggacac cgtgtacatc atcctctcgc tcccgaacgg gcaggtcatt gtccgggggc
     7621 ggtactccac cgggataccc gcaacggtct cctcgatcga gaagagttgt gccgtccgca
     7681 ttcttgggat ccagggaaaa gaaaagtcca ttatctaccc cgatggggag agcgccgtcc
     7741 atgcaggcga catactgctc gtaatgggtt ttccccgggg gctgcgaaag ttcatcaggg
     7801 tcacccagag agatctcctg tgaggcgaat ggacgaggaa gcagggtgtg cactcgggag
     7861 gatcgaacag ctcctcaggt atgtttactg gaagagcggg agcaggggtt atgtcatcgg
     7921 ggtctcgggc gggatcgatt cagccgttgc cgcaaccatg tgctgcaggg cagtcgggcc
     7981 ggagcgggta ctcggtctca tcatgcccag cggcgtttcg gaaccttccg atatctccga
     8041 tgccggggag gtgtgccaaa ggctttccat ggatttccgg acgataagca tcgagcccgt
     8101 cctttctgcg taccggtcgg ttccggggtt tcaggatgac cggacgctcc ttggaaacct
     8161 gatggcccgc acccggatgg caattctcta ttaccatgcc aaccggctgg ggatgctcgt
     8221 ctgtgggaca tcgaacagga ccgagtacat gatcgggtat tgcacgaagt ggggggacaa
     8281 cgcggcggac gtccagccca tcctccacct ctacaagaca gaggtctacg aactggcagc
     8341 aacgatggaa aacatcccgg aacgcgtgct ccgcaaggtg ccgtctgcag ggctgtggaa
     8401 gggccagagc gacgaggccg agattggact gagctatccc gagatcgatg ccgcattaaa
     8461 atcactcgaa caaaacggat ggaccagcca aaaccccgtc gaagaccggg tcctctccat
     8521 ggtcagggca agcgagcaca agcgccgccc agccccgagt ctcctatagg atggaaaggg
     8581 tgtgcatgta cctctcggga tagacgaggg cacagagtat ctcgtccctt ctctccacgt
     8641 atccgtacag ggagccgtca cgccatggcc cgggggttat ttcgtgcggt tgccgcgtct
     8701 ctgccggggg aacggaagga tagcgtgggt tcttctcgag ttcccccgag acgagctcgt
     8761 agtacgcggc tccgcggttc tcctcgtaga accggtagtc gctctcaaaa caggaggaga
     8821 cgatatttgc catcacgagg tcgccttctc ccgggttgat ggtgacatgc ccgtaccccg
     8881 gcggaacaag gactgtctcg ccctcccctg ccggaacgag gacgatcctc ccgagatcgc
     8941 ggcgctggag gagaaaatgg gccctccccg agaggacctg gtagacctcc ggatacccca
     9001 taccggacgg gttgtccggg tgatagtgcc cctttgtctt gacgaactcg ccgcagagat
     9061 cccggggagg gatgcaggtt acgtcatagc gcaggtgtct ctccgagagc catgccctgt
     9121 cgacgggtga ccgtgcgatg tcccggaaca tcaggtaggc agggccgtcc aggtcacagg
     9181 cggggttccg gaggacgggt ctgagatcct ccacgctccg ggtcaccggg gaccctgcat
     9241 acttcttcca gtcttccatc accctttctt ttggtttttc cgtatataat agaccgcacc
     9301 ggctgcaagc gcgacgagca cgaatatccc ggcaattgcg agcggagaga tccccggact
     9361 gacaaccttt acgcggacct tcatcgtgtc cgagatcacg ctgttatcga gggcatcccg
     9421 gtaccttatc tccgagtcga gtccgtattc cttgaggact gcccctgcgt ccacgttgac
     9481 ctcgtacagg gcgaccgccc tctcacccgg cgcgatgtcg ccaaggtagg ccgagtcatc
     9541 gttgctcgaa aaaggatcca cggcactgat tcgggcctgg gcgtcccggg ccgttgccga
     9601 accggtgttc tcgtagacaa cctttatcac ggtttttccc ccggccctgg cctcggccgg
     9661 gggagagaca acagcaaacg atatcttccc gctgaccggg acgccgacgg taaccgtgtc
     9721 agaggttacc gtatctccct cgttatttgt gtacttgcag aatatgtcga caggataaga
     9781 gccttcgctt gcctgccgcg atacagacac gcggaacctg acatcgcggg tgcttcccgc
     9841 ggggaattca ccgatgtaga tgttgctgtc tgtcgggacg atggggctgt tgccgttacg
     9901 ggagaggtaa accacggtgt cccgtgcatc ctcgtagccc ttattccgta ccgagaggga
     9961 gaggtacccc tccgttcccg cgttgagagc ctcgccactc attgcaatca cctcgagcat
    10021 tgccctcggc tgcacccgga ccatgagcgg gatcgtctct tcaacgtcgc ggtaggtgta
    10081 ggagatggca tcctgcccat actgctccgc agtcttcagg taggagtacc ggacatgcag
    10141 ggggagggta tagttccctg aaggagcgtc tgaagggatc tttgccgcga aggagacagt
    10201 ggcagacttc ccgcccggga tgtccccgac gacctgtggg tcggccttga tgatgaacgg
    10261 cgagtctccg gccccgaggg tcgctttcac gagctttgcc gtgttgggga gatcctccct
    10321 ctcgatgatc cctgactgga cgaacttcat atccaccagt ccccggttct cgatggttac
    10381 ccggagtgtg acgtcctctc cgggggaaaa ctcgtttctg ccctgaattg ctgcagagag
    10441 gtccggctct cccgcgaggt acttgactcc cgcgagggcc gggacacaca acagactgat
    10501 taaaacggcc agaaatacaa tacgccgcag attcatggga tatcacgtgt tgttattgct
    10561 ataacaacat ttaagagccg gccctatata atgctatgga atggctgaga ctccgtcccc
    10621 gtaccttgcc ctcaccgaga tactcaagtc ccttggctta acgaaatacg aggcgctggt
    10681 atacatcggt ctcctgaagg aaccgggcgc caccgcgaca cggatccacg aggtcgccgg
    10741 tgtcccccgc gcatcggtct accccgtgct cgggagactg atccagaaga acatggtctc
    10801 tgtctcgctt gccacaccgc gccgtttcga ggccgtccca cccgatgctg ccatcgacca
    10861 cctcctcgat gcagtctccg cggacgcagt acgggcaaag aagatgcttg ccaagatctg
    10921 gagggaacga aaccagaaag cacctgcaga ccaggactac atctggagca tctacgggat
    10981 agagaatatc cgggcgcgcc ttgcggacct gctgcgaaac gcaaccgttt cgatcgatgc
    11041 tgttctcttt ggtgatttgc cggaggatat ttgttccgtg ctctgcgaga aggcagcatc
    11101 cctccccgtg aaggtcacga cgaggaaccc ggaaaagttc gcctgccggg gaatcgaggt
    11161 gagtctcctc cctcctctcc ccaaagacgt cctcgacgtg gacacacggt ttacgggagg
    11221 atttttcctc atcgacgagg aacgggccat ggtcgtcata gtgaccggca ccgaggaggg
    11281 gactgcactc ttttcggaat cgaggggctt catcaggttc ttcctgtcat accgcgacct
    11341 cgtctcctcg cttgtgaaaa agatcggtca gtaatccagt atctcttcca ggtcgcggac
    11401 gtccatcagt cccttgatgg catgggtggt caccgcaatt cccctctcct tgatggcagc
    11461 catcgggttc gttccgccca gtgcaacgat gcccatgtac tgggggtcga cagtgacgcc
    11521 gagtgcgggt gtattcggca gaccaacgtc caggatgggt gaaaaactgc tccctgcaag
    11581 atcatcgatg acctccccga tctgcccttc ggcctccatg tgacactgcc tgatgttggc
    11641 aaggatgttt ccgcttcccc ggcgcatcat cccggtaacg gatgttatct cctgggaaag
    11701 gagagcctgg agcgggtcga tcgttgtgtg ctcgtacagg atgaggtgga tgaaccggcg
    11761 gggaatgcgc ccctctatct cgacaacccc gcccccgatg gggtttgacg ggatacccct
    11821 gcggaggagg ataccatcga gggtggaact gcatatcgtg atgattccgg tgtgtcccgc
    11881 cgggaccttt gtctctccgg cagttccgcc ttccccgaca aaccggacaa gcccgctcac
    11941 gcagagccct gccctgaacg tatccctcat cacggtgatt gcggcatcga ggtccccgtt
    12001 ttggacgaac gagagattgt ataccacgag cccccctcct tcccgggggt catatgtcac
    12061 ctgcatggca tactcctcga tccgggtatg cacgaacttg aggggaagat gcatttgcta
    12121 cgatctcgtc cccggaatag aaaaattgtt ctataagatg ggggaaatgt atgtttaatg
    12181 gacgaaaagg ttcgggaaaa ggcgaggaat gccataaaga caattctcga ggccgcagga
    12241 tacgaggttg acacgctgaa agacccttat gaccttgcca gccgggataa cgactatatc
    12301 atggttctct gcagcgatga cgaggatgag atcgctgatt ttgcgaacgg taacttccgg
    12361 ctcatgagcg gcggggaaga gatcacgtac aggaaactgc tcttttctct caatcccggt
    12421 gccggagcag aggggtgcac cgtctggggg cgggatgaat ttgtccgtct ctacggcgag
    12481 gctgccctcg cggggatact gtcacgtccg ttttccctgg ccatcggtgc aggggagagg
    12541 ggggggactg ccccgtccgt tccatcgcct gcagaacgcg gaaccgggga aggagaggag
    12601 gaggcgtccg gtgtcatcat cccgcacctg cccatccggg tgaagaagga tgctgccgtg
    12661 cagattgcaa agatgcaggg gacggtggcc ctgaagttca tgccgttctg gttctattcg
    12721 tacaggagtt cgggggagca ggtatacaag gaacaccgcg tcccgttcga tgccgagggg
    12781 gacggcgggc tcaatgccat caacgggctg aagttcgagg tggacgcaaa gtccctcgtc
    12841 gaggacgcgg tcccggccgg tgcggaagtc gtctctcccc gcatcacgca ggaggaggca
    12901 cgggaaaaga ttgcatcgga agtggccgag aacctgaccc agaggatacg gatcaagcag
    12961 gtgagcgggg atgccatctc ctacgaggag aaggtgctga aaccggacag gcggaacatc
    13021 gaggtcacgg tccggcaggt ctacgtcccc atctggcagg tccgcggcaa gaagatcgtt
    13081 gaagtcaacg cgttctccgg cgaagtcctc tcgtccccga tggacgaggg cgtggagatc
    13141 ttctagggcc gccacgcatg ataggagtcc ttgggggcgg gcccgcaggc cggactgcgg
    13201 caatgaaact cggcctcgcg ggaaaggatg tcaccctggt cgagaagggc gggctcggcg
    13261 gccagtgcct ccactatggc tgcatggtgg tctgtgccct caacgacgtc gcccgcaccc
    13321 tgcatactgc ccggaacctc catgcccttg gtatcctcga ccgtgtcccc tcgttctcat
    13381 tcccccgcac gatctcccag atggtatctg tccaggaaaa gatcactgcc atcctggatg
    13441 ccgagacgag ggggtgcgga gttgccatcg tgcggggaga agggagtgtc gagggaaatt
    13501 ccctctctgt cggtggaaaa gccctccaga cgtctgccct cgtcatcgcg accggctccc
    13561 tcccccggat cccttccatc ccgggggtcc aaaacccggg tgttttccat gcccattccc
    13621 tctcctcgat gcttgccgtc cccgaccgtc tcctgatcat cggcggtgga atcatggccg
    13681 cggagtttgc cttcatcttc cacgagtggg gggccgatgt cgatatcgcg gtccggagca
    13741 cgttcctccg cgaggttccg cgggtactgc gggaggccgc aaaaaaagat ctcgagggaa
    13801 ttgcgatcca cgagaactgc acggtgaccc ggatcgacgg ggaccccgcc gtcagaagtg
    13861 cgatcctcca atgccgggaa ggggagaagg agatcccctg cgatgccgtg ttccttgccg
    13921 ccggccttgt ccccaactcc cggatggtct cgggcatcag gaagggcgac gacgggagga
    13981 tcatcgtgga ccggcggatg gcaaccagtg tccccggcgt gtatgcctgc ggggatgtga
    14041 cagggtcgcc ctgcctgaca ccggtcgccc gccaggaagg catcgttgca gcgtcatcca
    14101 tcctcggcga ggacgtcctc atggactact cggcaattcc ccagtccgtt gccctcgccc
    14161 acgagtacgc cttcgtggac ggcgagccgg cagataacga agtcgccttc tcctccccgg
    14221 ggccggccgg gccggggacg ttctgggagg tcccgcgggg gagaaccggc atggcagaat
    14281 tgatcgtctc ccggcaggac ggtcgtatag ggggaatctc ggttgccgga cc
//
LOCUS       DAOOJU010000037        13527 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_4286_length_13527_cov_14.481072, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000037 DAOOJU010000000
VERSION     DAOOJU010000037.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 13527)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 13527)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13527
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4286_length_13527_cov_14.481072"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1074
                     /locus_tag="PK679_08085"
     CDS             <1..1074
                     /locus_tag="PK679_08085"
                     /inference="COORDINATES: protein motif:HMM:NF036704.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharyl transferase, archaeosortase A
                     system-associated"
                     /protein_id="HPC55948.1"
                     /translation="YELRVAGSGALRMNPDWRESLEWMEKNTPDPGVDYYRIYQKETF
                     RYPPESYGVMSWWDYGHLITYIAKRIPNANPFQSGVAGENGAAAFFMTADEERNSEIA
                     KALGVRYVMTDVEMDIGKFWAMATWFNTSAGLSPYTEVILVPGQGGTETYSPVEMYEA
                     PYFVTMISRLHNFDGSMADAKQVYYVEVDESRTTYPVATKALAMDPQAALEAADAYNR
                     DAAPGKRALVISPDIRIPVGKVPALRHYRLVHESPTNILAKAQANASPDLITDMRYVK
                     VFEYVPGARIAGEGTIEVDVVTNTGREFTYRQESRDGTFIVPYATTGSPYEVRTKGKY
                     RIVGTGREFEVPEEAVLQGLPVG"
     gene            1075..2058
                     /locus_tag="PK679_08090"
     CDS             1075..2058
                     /locus_tag="PK679_08090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase"
                     /protein_id="HPC55949.1"
                     /translation="MAARCSVITGEEFTHHDLGWHEENSRRLLDAIAHIPSSLRRHHP
                     EQASFEDLARVHEPRHIRTIEELCSYGGRRYLDMDTYVTEESFRVATLAAGSSIAAVR
                     RALSGESCFALVRPPGHHAEPGRAMGFCLFNNAAVAAAWALERVDRVAIIDWDLHHGN
                     GTQKIFYGSDRVLFCSIHQANVFPWSGWIDEVGEGRGMGFTLNAPLVAGGGIGDYYCI
                     FSSVFCEALVHFDPDAVIISAGQDPLFDDPKGGMRLAPGDFGLLCSMVREAAGCPLAL
                     VLEGGYGPSLGKAVFSILDALQRDEPYPVPAGLRPRASTRRIARLLRKVMI"
     gene            complement(2122..3291)
                     /locus_tag="PK679_08095"
     CDS             complement(2122..3291)
                     /locus_tag="PK679_08095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HPC55950.1"
                     /translation="MEVELAHVRKVFCEGTHRAEVPGETEKAARSLMESAGVEKIQDL
                     TRKDRLGIPCFAARRRRAPRGGSPLLPGMGRTRLLARVSAMMAAIERHFGEYRGEPLE
                     CASYEEATIRGAIDPRSLILPRPPAPGEQIHWSSGKDLLTGEDVLVPSNAVFFPYESR
                     GLAMQLFPGDPVGLASGNAREEAILHGLLELLELDSLSRAERRRDMGRRIAVDTPGPV
                     QDLLDKFGKAGVEIHLWLIGGRTRVPVVAAAADDPGARDPGLLIMGSACHPDPAIAVE
                     RALLDVAFSRASYLAGVLSSPRRDMLLARAGYERMKRINHEWFAPAPEVALSSIPGCS
                     TRWFDEDIVLILDDLQAIADHVCIVDLKSAPLPVVRVVVPGLEVSHLHKDRRVSS"
     gene            3348..3641
                     /locus_tag="PK679_08100"
     CDS             3348..3641
                     /locus_tag="PK679_08100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2098 domain-containing protein"
                     /protein_id="HPC55951.1"
                     /translation="METGEAAVGMRVRYPRTGTTGTIVSLTVEGGKTFAELDTTRLLY
                     RVDQLVPAVNVGERKEGALEDTVEKIKKEREFYSGTGFQEAISHTDQSCEGGG"
     gene            complement(3638..4060)
                     /gene="nikR"
                     /locus_tag="PK679_08105"
     CDS             complement(3638..4060)
                     /gene="nikR"
                     /locus_tag="PK679_08105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010045 - response to nickel cation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HPC55952.1"
                     /translation="MTVDTELSRIGISLPKNLLDKFDEIINYRGYSSRSEGIRDAIRN
                     YITYYKWMSDVKGERQGVITMIYDHGQRNLLTTLTDIQHEFMGIIQASLHSHVTHDRC
                     LEVVLVRGDGSQLKALAERLMSQKGVESVKLTTIPLND"
     gene            4205..4879
                     /locus_tag="PK679_08110"
     CDS             4205..4879
                     /locus_tag="PK679_08110"
                     /inference="COORDINATES: protein motif:HMM:NF025053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C domain-containing
                     protein"
                     /protein_id="HPC55953.1"
                     /translation="MEGEKMGHLEFFGFSEKGLRERNEDAFLAADLGEMYVFAVAEGM
                     GGPKEGPTAAQIAVDALGAGGAAREKTLAGTLEQLLGRAERALYSLEAENPGIEPSGV
                     ALGVAIISPGGECVVSSPGSRKVFFLAEEEKGTAPDAASAGQGQLTLHDPGPGMHEAT
                     LPPGYLVLCSDGISDFIPDSRIVEIVAERGDDLEDACRKLVYEAFQNGSDDNLTVVLV
                     RRRASS"
     gene            4920..5810
                     /locus_tag="PK679_08115"
     CDS             4920..5810
                     /locus_tag="PK679_08115"
                     /inference="COORDINATES: protein motif:HMM:NF016214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HPC55954.1"
                     /translation="MDSITHALVAILVFSNPLQGAALLSAVLGAVLPDCDVLLHALSD
                     RDPRLFIFTHGGFTHSLGGIPFIAAGVTAGFLAWAGATGQDPPLPAIMGTIFFPALGG
                     ALTHVTLDLLAFPGIPLLYPLRERKMTVGIFPGPSILLLLTSIGFLCLFLFGLATMQW
                     LQGYGVFIAGIVVARAGLRGIAETRFGRRTVPTFNPLKWLVIRDCGDAYRVFFTYLFS
                     SPKEEQVYPKGSAGFPGNLSGHVRDPEVRRLLYNSYVLVARREEGGTLLYDPLREDGF
                     IFYPPRHTRVFLRDEEAREG"
     gene            5966..7201
                     /locus_tag="PK679_08120"
     CDS             5966..7201
                     /locus_tag="PK679_08120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 subunit
                     gamma"
                     /protein_id="HPC55955.1"
                     /translation="MHDVTIPSVNIGVVGHVDHGKTTLVYGLTGMWTDRHSEEIKRGI
                     SIRLGYADATFYRCERCEGPDSFGTQPECPVCGGKAVAFRSVSFVDAPGHETLMATML
                     SGSALMDGAMLVIAANETCPQPQTKEHLMALQLVGIRNIVIVQNKIDVVSQKEALRHY
                     EQIRAFVKGTIAENAPIIPVSAQKAINMGALVEALDQTIPVPERDPNAEPLMLLARSF
                     DVNKPGSNWRDLKGGVIGGSLIRGILRESDDIEIRPGLQVQAENRFRWEPIETKITTI
                     NAGSRKVTEATPGGLLGIGTKLDPALTKSDALAGQVAGHPGKLPPVWDRIRFRVTLME
                     RVVGASSETQIEPLKHNEPLMLSVGTAVTVGIVVNTRKDIVETTLKRPVCAETGARIA
                     ISRQVGGRWRLIGMGVLTE"
     gene            7198..7578
                     /locus_tag="PK679_08125"
     CDS             7198..7578
                     /locus_tag="PK679_08125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide-binding protein"
                     /protein_id="HPC55956.1"
                     /translation="MKVLFDSNALMIPSQFRVDVFEELGNIIGAYEPLILTEALRELA
                     GLSRGHGSEGSAARFALTLAGRCHEVPSGYAGGSVDEKILRYAREHGCMVVTNDRGLR
                     DLLLSAGVPVITLMHKKKLGLLKR"
     gene            7595..8185
                     /locus_tag="PK679_08130"
     CDS             7595..8185
                     /locus_tag="PK679_08130"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HPC55957.1"
                     /translation="MYYKMEMSDKVRVPPHRMGEELSRVILDVLQEHLEGSIDKEIGI
                     FIAVTRVITIGEGEIVPGDGAIYYDVDFEAVVLRLSLQEVIEGLVVETTSFGAFVSLG
                     PIDAMLHVSQISDEYINYDEKNARLICQDSKRFIGVGEPVRVRVVTLSLNEREPRDSK
                     IGLTMRQAGLGTARWLEEDMLKEKEKAKGGGERGSR"
     gene            8172..8375
                     /gene="spt4"
                     /locus_tag="PK679_08135"
     CDS             8172..8375
                     /gene="spt4"
                     /locus_tag="PK679_08135"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003711 - transcription elongation factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor subunit Spt4"
                     /protein_id="HPC55958.1"
                     /translation="MAAARKKLVTVCRECHRVVEGEACPICGTSNLSTDWAGYLVIID
                     PKNSEIARKMNITLPGRYALKVR"
     gene            8486..8881
                     /locus_tag="PK679_08140"
     CDS             8486..8881
                     /locus_tag="PK679_08140"
                     /inference="COORDINATES: protein motif:HMM:NF015952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-dependent dephospho-CoA kinase family
                     protein"
                     /protein_id="HPC55959.1"
                     /translation="MGDIVTHNALKHGIVPGIAVVDGHTMRKPCNRVPAVFPRVLSAV
                     NPAGTITRDLVDTLKAAVSSPPALIIVEGEEDLAVIPLALILAPGSIILYGQPGEGVV
                     IRKIDESARTEARRLLACFVPGDDGGLEL"
     gene            9018..9314
                     /locus_tag="PK679_08145"
     CDS             9018..9314
                     /locus_tag="PK679_08145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S24e"
                     /protein_id="HPC55960.1"
                     /translation="MEIEVTRDNRNELLGRREVDFVLRFDGPTPSRLQVLGKLAAMLN
                     AKENQVALDSLKTSFGMTSCTGNARIYDTEELRNRTEREFLLKRGVPKPKEEGA"
     gene            9319..9507
                     /locus_tag="PK679_08150"
     CDS             9319..9507
                     /locus_tag="PK679_08150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S27ae"
                     /protein_id="HPC55961.1"
                     /translation="MAAKKKAKAKKPGRGTYYSVSGGKVAFSRKFCPRCGPGIILAEH
                     PDRAACGKCGYTEFRKAA"
     gene            9571..11142
                     /locus_tag="PK679_08155"
     CDS             9571..11142
                     /locus_tag="PK679_08155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional N(6)-L-threonylcarbamoyladenine
                     synthase/serine/threonine protein kinase"
                     /protein_id="HPC55962.1"
                     /translation="MPDIGPVLGIEGTAWNLSAALFDKDLISLYSKPYMPPQGGIHPR
                     EAAQHHATFMKEVIARVMPPSGKIAGVAFSMGPGLGPCLRTVATAARALALALDVPLV
                     GVNHCVAHVEIGRFATGARDPIVLYASGANTQVIGYLNQRYRIFGETLDIGLGNALDK
                     FARSRGLPHPGGPEVERLALKGGYVELPYTVKGMDLAFSGLVSAAKDHPAPLEDVCNS
                     LQETAFAMCVEVTERALAHAGKDEVLLVGGVGANRRLQEMLATMCSERGAVLHVPDRK
                     FMGDNGAMIAYTGRLMLGRGITMPPGETRANPVFRADQVEVTWWDGGTVQGARRAGEP
                     GVARGAEAIVRVGPDVVEKQRQKKSYRQPSLDARLISERTRAEARLISMARRHGVPTP
                     VIRDITADTIVMERIQGPLVRDQLSGENMYLAGKTVGRLHSAGIVHGDLTTSNMICRD
                     GQCFLIDFGLAQVSGELEARGVDLHVLFQTLESTTDNHAALKESFLKGYRAECAFADE
                     VIVREQEIERRGRYL"
     gene            11139..11681
                     /gene="rdgB"
                     /locus_tag="PK679_08160"
     CDS             11139..11681
                     /gene="rdgB"
                     /locus_tag="PK679_08160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RdgB/HAM1 family non-canonical purine NTP
                     pyrophosphatase"
                     /protein_id="HPC55963.1"
                     /translation="MKITVVTNNPHKAREIGLFFGGVAEVTHVALECPEVRDNSVKTI
                     AEKKAEYAYQILKRPLICDDTGFYIHALRGFPGPYAAFVQETIGNEGILRLMEGVSDR
                     KAFFETAIAYADGDDIRVFSGRIQGRVVAPRGTGGFGYDPIFEWRGRTLAEMSPEEKN
                     RVSHRARALRRLRDFLIARV"
     gene            11773..11919
                     /locus_tag="PK679_08165"
     CDS             11773..11919
                     /locus_tag="PK679_08165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L40e"
                     /protein_id="HPC55964.1"
                     /translation="MARFPEAEARLLNVKICMKCNARNALRATRCRKCGYQHLRPKNK
                     ERKA"
     gene            complement(11924..12574)
                     /locus_tag="PK679_08170"
     CDS             complement(11924..12574)
                     /locus_tag="PK679_08170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1917 domain-containing protein"
                     /protein_id="HPC55965.1"
                     /translation="MSEIDPDSLSDLACGLFFHLLNRELHDRGLVLFSLVENRVDFRD
                     AFLEVFRSFCADYPDLGEAMEKKYGGPEGVYGLICQGEGVIPGKTTTMHWIVQDAPGV
                     SPDAIEDELAGKWLIFVPPAEVDSAWARVRDATCRGELGISSKVSTARPDPDSRDERK
                     VIYVYTRDWRDEADVMRVREKLRELGFTERIGYKRNIETYRGEYSERGKKVTYYSA"
     gene            complement(12619..13383)
                     /locus_tag="PK679_08175"
     CDS             complement(12619..13383)
                     /locus_tag="PK679_08175"
                     /EC_number="2.4.2.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide-dependent adenosine diphosphate thiazole
                     synthase"
                     /protein_id="HPC55966.1"
                     /translation="MELDEITISRAIVASYLEKFLDFMEMDVAVVGAGPSGLTAAALL
                     AERGHRVGIIEKKLSVGGGMWGGGMMFPRIVVQEEARRLLDRFAIRYTPYREGYYVSS
                     SVEAVSKLTAAACDAGVEFFTLFSVEDVMIHGDGRLSGLVLNWTPVEMAGLHIDPLTM
                     GCRVAVDATGHDAVLARLVERKGGEIRVKGESFMWAHRAENEILSHTREIFPGLVACG
                     MAANAIAGEHRMGPVFGGMLLSGERAAALAGSLLRT"
BASE COUNT         2820 a         3874 c         4254 g         2579 t
ORIGIN      
        1 tacgagctcc gggtggccgg ttccggagcg ctccgcatga accccgactg gcgcgagtcg
       61 cttgagtgga tggagaagaa cacgccggac ccgggtgtcg actactaccg catctaccag
      121 aaggagacgt tccggtaccc gccggagtcg tacggtgtca tgtcgtggtg ggactacggg
      181 cacctgatca cgtacatcgc aaaacgtatc ccgaatgcaa accccttcca gtcgggagtg
      241 gcaggagaaa acggtgcagc cgcgttcttc atgacagcgg acgaagagag gaacagtgaa
      301 attgcaaaag ccctcggtgt ccggtacgtc atgacagatg tcgagatgga catcggcaag
      361 ttctgggcga tggcaacatg gttcaatacg agtgcaggtc tatcgcctta cacagaggtc
      421 atccttgtgc cgggccaggg gggcacggaa acgtattcac cggtcgagat gtacgaggca
      481 ccgtatttcg taaccatgat ctcgcgactc cacaacttcg atggttccat ggcggacgca
      541 aaacaggtct actacgtcga ggttgacgag agccggacaa catatccggt tgcaacaaag
      601 gcacttgcca tggacccgca ggccgctttg gaagccgcag acgcctataa cagggatgca
      661 gcacccggca aacgggccct cgtcatctct cccgacatcc ggataccggt cgggaaggtg
      721 ccggcattga gacactaccg gctcgtccac gagtccccca cgaatatcct tgcaaaggca
      781 caagccaacg cgtcaccgga cctgatcacc gacatgaggt acgtcaaggt ctttgagtat
      841 gtccccggtg cccgcatcgc aggtgagggg acaatcgagg ttgatgtcgt gacgaacacc
      901 ggcagggagt ttacctacag gcaggagagc cgggacggca cgttcatcgt cccgtatgcg
      961 acaacgggat cgccctacga ggtaaggacg aaggggaaat accgcattgt cgggacaggg
     1021 agggagttcg aggtccccga ggaggcagtc ctgcaggggc tcccggttgg gtgaatggct
     1081 gcccggtgct cggttatcac aggggaagag ttcacgcacc atgacctggg ctggcacgag
     1141 gagaacagcc ggcggctgct ggatgcaatt gcgcacatcc cgtcctcact aaggaggcat
     1201 cacccggagc aggcatcgtt cgaagacctt gcccgggtgc acgagccacg gcatatccgg
     1261 actatcgagg aactctgctc gtacggcggc aggaggtacc tcgatatgga cacgtacgtg
     1321 accgaagagt cgttccgggt tgcgacactg gctgccgggt cgtccattgc ggcggtgagg
     1381 cgtgccctct cgggagagtc ctgttttgcc cttgtccgcc ctcccggtca ccacgcggaa
     1441 cccgggaggg cgatggggtt ctgcctcttc aataatgccg cggtcgctgc agcatgggcg
     1501 cttgaacggg tggaccgcgt cgcaatcatc gactgggacc tgcaccacgg gaacgggaca
     1561 cagaagatct tctacgggag cgaccgcgtc ctcttctgtt ccatccacca ggccaacgta
     1621 ttcccgtggt ccggctggat cgatgaagtg ggagaaggca ggggaatggg ttttacctta
     1681 aacgctcccc ttgttgcggg gggagggatc ggtgactact attgcatctt ctcgagcgtg
     1741 ttctgcgagg ccctcgtcca tttcgacccg gacgcggtga tcatctcggc cgggcaggac
     1801 cctctgtttg atgacccgaa gggagggatg cgtcttgctc ccggggattt cgggctcctc
     1861 tgttccatgg tccgggaagc cgcgggatgc ccgctcgcac tcgtcctgga aggagggtat
     1921 ggtccgtccc tgggaaaggc agttttttcc atcctcgatg ccctgcagcg ggacgagcct
     1981 tatccggttc ccgcggggct ccgcccgagg gcgagcacga ggaggatcgc aaggctcctt
     2041 cggaaagtga tgatctgaaa aaaacccgcc cgctggcagg atgcagacgc ccggggcagg
     2101 tgatggagaa ggaaatcccg gtcagctgct cacccggcgg tccttgtgga ggtgcgaaac
     2161 ctcgaggccg ggaacgacca ccctgacgac cgggaggggg gcggatttga ggtcaacaat
     2221 gcagacatgg tctgcgatag cctgcaggtc atcgaggatg agcacgatat cctcgtcgaa
     2281 ccaccgggtg ctgcaaccgg gaattgagga gagagcaacc tccggggcag gcgcaaacca
     2341 ctcgtggttg atccttttca tgcgctcgta cccggcacgg gcaaggagca tgtcacgccg
     2401 aggtgacgag agtacgcccg cgaggtagga cgcccgggag aaggcaacgt cgagaagtgc
     2461 cctttcaact gcgatcgcgg gatcgggatg gcaggccgag cccatgatga ggaggcccgg
     2521 gtcccttgcc cccgggtcgt ctgcagcggc tgcaacaaca gggacccgcg ttcgtccccc
     2581 gatgagccag aggtggatct ccacacctgc tttcccgaac ttatcgagga ggtcctgcac
     2641 aggtccgggt gtatcgaccg cgatcctcct gcccatgtct ctcctgcgtt ctgcacggct
     2701 cagggagtca agttcgagga gctcgaggag cccgtgcagt attgcctctt cccgtgcgtt
     2761 gccactggca aggccgaccg ggtcgcctgg gaagagctgc atggcgagtc cgcgcgattc
     2821 atagggaaaa aagacggcgt tgctcgggac gaggacatct tcgccggtga ggagatcctt
     2881 tccggaagac cagtggatct gctctccggg ggcaggcggc cggggaagga tgagggaccg
     2941 cggatcgatc gcaccgcgaa tcgtggcctc ttcgtaactg gcgcattcca ggggttcacc
     3001 cctgtattca ccgaaatgcc gttctattgc cgccatcatt gccgatacgc gggccaggag
     3061 gcgggtccgt cccatgcccg gcaggagggg actgcccccg cggggagccc ggcgtcgccg
     3121 ggcggcaaaa caggggatgc cgagacggtc cttccgcgtg agatcctgta tcttctccac
     3181 gccggctgat tccatcaggg accgtgcagc tttttccgtc tcccccggta cctctgccct
     3241 gtgggtcccc tcgcagaata ccttccgcac atgggcaagt tcgacctcca tcatatcccg
     3301 tgggggcggg aagagtttta tattttccac gcacccgtca catgtgtatg gagactggtg
     3361 aggcagcagt gggaatgcgg gtgcgatacc cgcggacggg gacgaccggc accatcgttt
     3421 cgctcactgt cgagggcggg aagacatttg ccgaactcga caccacccgg ctcctctacc
     3481 gggtcgacca gctcgtccct gcggtgaacg tgggtgaaag gaaagaggga gccctcgagg
     3541 acacggttga aaagataaag aaagagagag agttctactc gggaaccggg ttccaggagg
     3601 ccatcagcca cacggaccag agttgtgagg gtggtggtta gtcgtttagg ggtatcgtcg
     3661 tcagtttgac ggattcaact cctttttgtg acatcaggcg ctcggcgagg gccttcagct
     3721 gcgaaccatc ccccctgacg agcacgacct caaggcacct gtcatgggtt acgtgggagt
     3781 ggagcgatgc ctggatgatg cccatgaact cgtgctggat gtccgtgagg gtggtcagga
     3841 ggtttcgctg accgtgatcg tagatcatgg tgatgacacc ctggcgttct cccttcacgt
     3901 ccgacatcca cttgtagtag gtgatatagt tccggattgc gtccctgata ccctcggacc
     3961 gcgaggaata tcccctgtaa ttgatgatct cgtcgaactt gtccagcaga tttttcggga
     4021 gcgaaatgcc gatccgggag agttcagtat caacagtcat ggttcattgc ctcttctcaa
     4081 agactgtctt cttatattat aacttaaaac ttcgtaaaac aggatctcca aaatggcaat
     4141 ttgtggtact ggtcagccat gaggagccgt ttatacatgt ttaataggct cggggaacac
     4201 acgcatggag ggagaaaaga tgggtcacct tgagttcttc ggcttctccg agaagggcct
     4261 gagggagaga aatgaagacg cattccttgc agcggatctc ggcgaaatgt acgtctttgc
     4321 tgtcgctgaa gggatgggcg gaccaaagga aggtccgact gcagcccaga tcgcggtgga
     4381 cgcgctcggc gcaggagggg ccgcgcggga aaagacactg gccgggacgc tcgagcaact
     4441 ccttggacgg gccgaaaggg ccctctacag cctcgaagca gagaacccgg gaatcgagcc
     4501 ttccggtgtg gcgctggggg ttgccattat cagccccggt ggcgagtgcg ttgtcagcag
     4561 tcccggttcc cgcaaggtct tcttcctcgc ggaagaagag aaggggaccg ctcctgacgc
     4621 cgccagtgcc ggacaagggc agcttaccct ccatgatccc gggccgggca tgcacgaggc
     4681 gactcttcct cccggatacc ttgtcctctg ctctgacggg atttcggatt ttatcccgga
     4741 ttcccgcatc gtggagatag tggcagagag gggtgacgac cttgaagacg cctgcaggaa
     4801 gctggtctat gaagcattcc agaacggaag cgacgacaac ctcacggttg tcctggtccg
     4861 gcgcagggcc tcgtcctgat ggggtgtgtt ccggctgaca accggaaggg aaaggttccg
     4921 tggacagcat cacacatgcc ctggtcgcca tcctggtttt ttccaacccc ctccagggag
     4981 cggctctcct ctcggcggtt ctgggagcag tccttcccga ttgcgatgtt ctccttcatg
     5041 ccctgtctga tcgcgatcca aggctcttta ttttcacaca cgggggtttt acccacagcc
     5101 tcgggggcat tcccttcata gcagcaggag tcacagcggg tttccttgca tgggcaggtg
     5161 cgaccgggca ggaccccccg ctcccggcaa tcatgggaac gatctttttt cccgcactgg
     5221 gcggagcatt gacccacgtg acccttgacc tcctcgcttt ccccggcata cccctcctgt
     5281 accctctgcg ggaaaggaaa atgacggttg ggatattccc cggaccgagc attctcctcc
     5341 tcctgacaag catcggtttc ctctgccttt ttctcttcgg gctggcaacg atgcagtggc
     5401 tgcagggtta cggggtgttc atcgcgggta tcgtggttgc ccgtgcggga ctgaggggca
     5461 ttgctgaaac ccggttcggg agaagaacag tcccgacatt caaccccctg aaatggctgg
     5521 tgatcaggga ttgcggggat gcctaccgcg tcttcttcac gtacctgttc tccagtccca
     5581 aagaggaaca ggtgtatccc aaaggcagtg cgggcttccc ggggaacctt tccggacacg
     5641 tacgggatcc ggaggtacgg cggctcctct acaattcgta cgttctggtc gcaaggaggg
     5701 aggaaggggg aacgctcctt tatgatcccc tccgggaaga cgggttcatc ttctacccgc
     5761 cccggcatac ccgggtcttt ctccgtgacg aagaggcccg ggaagggtga acctttcgcc
     5821 catggaaaga gagcaatccc catgcaaagt gccggggatc gtcatgtgtc ccatagccgg
     5881 aaaggacgag cgaggggcag aaatccccgt tcaatgagta ttaagtaggt gtgtttttat
     5941 attgaatagg gaggttcgat tggcattgca tgacgtgaca attcccagcg taaacatcgg
     6001 cgtggtgggg catgtggacc atggaaagac gacactggtc tatggcctga cagggatgtg
     6061 gacagaccgc cacagcgagg agataaagag aggtatttcg atacgcctgg gatacgcaga
     6121 tgccacgttc taccggtgcg aacggtgcga gggtccggac tctttcggga cacagccgga
     6181 atgcccggtc tgcggcggaa aagccgttgc cttccgttcg gtgtccttcg tggacgcacc
     6241 cggccacgag acgctcatgg cgacgatgct ctcggggtct gccctgatgg acggggcaat
     6301 gctcgtcatt gctgcaaacg agacgtgtcc ccagccccag acgaaagaac acctgatggc
     6361 gctccagctc gtcggcatcc gcaacattgt cattgtccag aacaagatcg atgtcgtctc
     6421 ccagaaggag gcactcaggc actacgagca gatccgggct ttcgtcaagg ggacaattgc
     6481 cgagaacgca ccgatcatac ctgtctctgc ccagaaggcc atcaacatgg gggctctcgt
     6541 cgaggcactc gaccagacaa ttcccgttcc cgaacgcgat ccgaatgcag aaccgctgat
     6601 gctgctggcg cggtctttcg atgtcaataa gcccggttcg aactggcgcg acctcaaggg
     6661 cggggtcatc ggagggtcac tgatcagggg cattctccgg gagtccgatg acatcgagat
     6721 ccggcccggc ctgcaggttc aggcagagaa caggttccgg tgggagccga tagagactaa
     6781 gatcacgacc atcaatgcag ggtcacggaa ggtaaccgag gcaacgccgg gcgggctcct
     6841 cgggatagga acgaaactgg accctgcact gaccaagagc gatgcccttg caggccaggt
     6901 ggccggccac cccggaaaac tcccgccggt gtgggacagg atcaggttcc gcgtcaccct
     6961 catggaacgc gtggtcgggg ccagcagcga gacacagata gaacccctca agcacaacga
     7021 accgttgatg ctctctgtcg ggacggcggt gacggtgggg atcgtggtca acacgcggaa
     7081 ggatattgtc gagactactc tcaagagacc ggtatgcgca gagaccgggg cccgcattgc
     7141 catcagccgc caggtgggag ggagatggcg gctgatcggg atgggcgtcc tgaccgagtg
     7201 aaggtcctct ttgattccaa tgccctgatg ataccctcgc agttccgggt ggacgtcttt
     7261 gaggagctcg gaaacattat tggggcatat gaaccattga tactgacaga agctctccgc
     7321 gagctcgcgg ggctctcccg gggccatggg agcgagggga gtgctgcgcg gttcgcgctg
     7381 accctcgccg ggaggtgcca cgaggtgccg agcgggtatg ccggcgggag cgtggacgaa
     7441 aagatactga ggtatgcccg ggagcacggt tgcatggtgg tcacgaacga caggggtctg
     7501 cgagacctcc tgctctctgc gggagttccc gtgatcaccc ttatgcacaa gaaaaaactt
     7561 ggtttattga agaggtaacg ggagagagtg gcgcatgtac tacaagatgg agatgtctga
     7621 caaggtgcgg gttccaccgc accgcatggg cgaggagctg tcccgggtga tactggatgt
     7681 cctccaggag cacctcgaag ggagtatcga caaggagatt gggatattca ttgccgtaac
     7741 ccgggtcatc acaatcgggg agggcgaaat cgtccccggg gatggcgcca tctactatga
     7801 cgttgacttc gaggccgtcg tgctcaggct ctctctccag gaagtgatcg agggactcgt
     7861 ggtggagacc acgagtttcg gtgcgttcgt gagcctcggt cccatcgatg ccatgctcca
     7921 cgtcagccag atatccgacg agtacatcaa ctacgatgag aagaacgcgc ggctcatctg
     7981 ccaggactca aagaggttca tcggtgtggg ggaacctgtc agggtccgcg tggtcaccct
     8041 ctccctgaac gagagagagc cccgggacag caagataggc ctgaccatgc gccaggcggg
     8101 tctcgggacg gcacgctggc tcgaggagga catgctgaag gagaaggaga aagcgaaggg
     8161 cggtggagaa cgtggcagcc gctaggaaga agctcgttac ggtctgcagg gagtgccacc
     8221 gggtcgtcga aggggaggca tgccccatct gcgggacgtc caacctgtcg acggactggg
     8281 cagggtacct ggtcatcatc gacccgaaga actcggagat cgccaggaag atgaatatca
     8341 ccctccccgg aaggtacgca ctgaaggtcc gctgatgctc cgactcccgg accgtcaccg
     8401 tcaccacttt aaggccccct ttgggagact cgaacccgat ttcagctgca tagtcccgga
     8461 aatcgggaat tcttttgtct gtactgtggg agacatcgtc acccataatg ccctgaaaca
     8521 cgggatcgtc cccggtatag cggtcgtcga cggccacacg atgcgaaagc cgtgcaaccg
     8581 cgtccctgcc gtttttccaa gagtcctctc tgcagtaaac cctgcaggca ccatcacgcg
     8641 ggacctcgtc gatacgctga aggccgcagt ctcctccccg ccggccctca tcatcgtgga
     8701 gggcgaagag gatctcgccg tcatccccct tgcgctcatt ctcgctcccg ggagtatcat
     8761 cctctacggc cagcccgggg aaggggttgt tatcagaaag atagacgagt ccgcaagaac
     8821 agaggcccgc aggctccttg cgtgttttgt tcccggcgac gatggcggac tcgaactatg
     8881 acccgatccc cctgcgatcc ggaaaggaac gtgcccggga agcctgcgaa aatgcatcac
     8941 cgtggcgttt cgggggcagc gagataggat ataaataacc cgggcgcgta taataagagg
     9001 ataccgagag gataccaatg gagatcgagg ttaccaggga taaccggaat gaactgctcg
     9061 ggcgaaggga ggttgacttt gtccttcgct tcgatggtcc gacaccatca cgcctgcagg
     9121 tcctgggaaa gcttgcggca atgctgaatg ccaaggagaa ccaggtcgcg ctggactccc
     9181 tgaaaacgag tttcgggatg acctcctgca caggaaatgc acgaatttac gataccgagg
     9241 aactgaggaa caggacagag cgggagttcc tcctcaagcg cggcgtcccg aaaccgaaag
     9301 aagagggggc gtagaaccat ggcggcaaag aagaaggcga aggcgaaaaa acccggcagg
     9361 gggacctatt actctgtctc cggtggcaaa gtcgcgttct cccggaagtt ctgcccccgc
     9421 tgcggcccgg ggattatcct tgccgagcac cctgaccgcg cagcctgcgg gaagtgcggg
     9481 tataccgagt tccggaaggc agcctgaagg gacaccggca cctgacacct gcacggttcg
     9541 ggaggcagga ccgtcccggg aacactcatc atgccagata tcggcccggt cctcgggatc
     9601 gagggaacag cctggaacct ctccgccgct ctttttgaca aagacctcat ctcactctac
     9661 tctaagccct atatgccccc gcaggggggg atacaccccc gggaggctgc gcagcaccat
     9721 gcaaccttca tgaaggaggt cattgcccgc gttatgcccc cttcggggaa gattgcggga
     9781 gttgcgttct ccatgggtcc cggcctcggc ccctgccttc ggaccgttgc aactgctgcg
     9841 cgggcgcttg cgcttgccct cgacgtcccg ctcgtgggag tgaaccactg cgttgcccac
     9901 gtggagattg ggcggtttgc caccggtgcc cgtgacccga tcgtcctcta tgccagcggc
     9961 gcaaacacgc aggtgatcgg gtacctcaac caacgttaca ggatattcgg ggagaccctg
    10021 gatatcggcc ttggaaatgc gctggacaag tttgcacgga gcaggggtct tccccatccc
    10081 ggtggtcccg aggtcgaacg gctcgccctg aaaggcgggt acgtggagct gccctacacg
    10141 gtcaagggca tggatcttgc cttctcaggg ttggtgagcg ctgcaaagga ccacccagcc
    10201 cccctcgagg acgtctgcaa cagcctccag gagaccgcgt ttgcgatgtg cgtggaggtg
    10261 accgagaggg cgcttgccca tgcaggcaag gacgaggtcc tgctcgtcgg gggtgttgga
    10321 gcaaaccgcc gcctgcagga gatgcttgcc acgatgtgca gcgagagggg ggcagttctc
    10381 cacgtgcctg acaggaagtt catgggagac aacggggcga tgattgccta tacggggagg
    10441 ctcatgctcg gcaggggtat aaccatgcct cccggggaga cccgggcaaa tcccgtgttc
    10501 cgggcggacc aggtcgaggt cacgtggtgg gatggcggga cggtacaggg agcgcggaga
    10561 gccggggaac cgggggtcgc ccggggtgcc gaggccattg tcagggtcgg tcccgacgtt
    10621 gttgaaaagc agcgccagaa aaagtcctac cgccagccct ccctcgatgc gcgcctcatc
    10681 tcggaacgga cgagggcaga ggcacgcctc atctccatgg ccaggagaca cggtgtcccg
    10741 acacccgtca tccgtgacat cacggcagac acgatcgtga tggagaggat tcaaggcccc
    10801 ctcgtcaggg atcagctctc cggcgaaaac atgtacctgg ctggaaagac ggtgggaagg
    10861 ctccattcag cagggatcgt ccatggtgac ctgacgacga gcaacatgat ctgcagggat
    10921 ggccagtgct tcctcatcga tttcggcctc gcccaggttt caggggagct cgaagcacgc
    10981 ggcgttgacc tccatgttct cttccagact ctggagagta cgacggataa ccacgctgca
    11041 ttaaaggaat ctttcctgaa ggggtacagg gcggaatgtg cattcgccga cgaggtcatc
    11101 gtgcgggaac aggagatcga gcggaggggg aggtacctgt gaagatcacg gttgtcacga
    11161 acaaccccca caaggcacgc gagataggtc ttttcttcgg gggggtggca gaggtgacgc
    11221 atgttgcact cgagtgcccc gaggtccggg acaacagcgt taaaacgatc gcggaaaaga
    11281 aggcggaata cgcgtaccaa atcctcaaaa ggccgctgat ctgtgacgat accgggtttt
    11341 acatccatgc actccgcggt tttcccggcc cctacgcagc attcgtgcag gaaacgatcg
    11401 gcaacgaggg tatcctgcgc ctgatggaag gggtctctga ccggaaagcc tttttcgaga
    11461 cggccattgc ctatgccgac ggcgatgata tccgcgtatt ttccggcagg atacagggaa
    11521 gggttgttgc gccccggggg acgggtgggt ttggatacga cccgatcttc gaatggcgcg
    11581 ggcgtaccct tgccgagatg tccccggagg agaagaacag ggtttcgcac cgggcccggg
    11641 ctctcaggcg gctccgggat ttccttatcg cccgggtata gggaagaagg taccggtctt
    11701 ttcgcggggg tacgcaaatc cttatgtgtt cgaaggacgt ttatttaaag actgaatctg
    11761 cggtgtttga ccatggcacg gttcccagaa gctgaagcac ggttgctcaa cgtgaaaatc
    11821 tgcatgaaat gcaacgcaag gaacgctctc cgcgcaacga ggtgccgcaa gtgcgggtac
    11881 cagcacctcc ggccgaagaa caaggaacgc aaggcctgat ccatcaggcc gaataatagg
    11941 ttaccttttt tccccgctcg ctgtattcac cgcgataggt ctcgatgttc ctcttgtacc
    12001 cgattctttc cgtaaaaccc agttcccgca acttttcgcg gacccgcatc acgtcggcct
    12061 cgtcacgcca gtcgcgcgtg tagacataga tgacctttcg ttcgtcccgc gaatcgggat
    12121 cgggtcgcgc ggtgctcacc ttcgacgaga tccccagttc tccccggcag gttgcatccc
    12181 gcaccctggc ccaggcagaa tcgacctcgg cgggcgggac gaagatgagc catttccctg
    12241 caagctcgtc ctcgatggca tccggggaga cgccgggagc atcctggacg atccagtgca
    12301 tggtcgtcgt ctttccgggt ataaccccct cgccctggca gatgagcccg tagaccccct
    12361 ccggtccgcc gtacttcttt tccatcgcct ctccgaggtc cgggtaatcc gcgcagaagg
    12421 aacggaatac ctccaaaaag gcatcccgga agtcgacccg gttctcgacc agagagaaga
    12481 ggacaagccc ccggtcatgg agctcccggt tcagcaggtg gaagaagagc ccgcaggcga
    12541 ggtcggagag cgaatccgga tcgatctcac tcatacatga aagttgcggg gatcggctaa
    12601 aaagggtatg gggatgcatc acgtccggag gagtgaaccg gcaagtgctg ctgcccgttc
    12661 tccggaaagg agcataccgc caaagaccgg ccccatccgg tgttcccctg cgattgcatt
    12721 ggcagccatg ccacaggcaa cgagcccggg gaagatctcc cgcgtgtgag agaggatctc
    12781 gttctctgcc cggtgtgccc acatgaaact ctctcccttc acccggatct cccctccctt
    12841 cctctcgacg aggcgtgcga gaacggcgtc gtgaccggtt gcatccacgg caacccggca
    12901 gcccatggtg agggggtcga tgtggagccc ggccatctcc acgggcgtcc agttcaggac
    12961 gaggcccgag agcctcccgt cgccgtggat catcacgtct tcgacggaaa agagcgtgaa
    13021 gaactcgaca cccgcgtcgc atgcagcagc cgtaagcttt gacacggcct cgacagagga
    13081 ggagacgtag taaccctccc ggtagggtgt atacctgatt gcgaaacggt cgaggagccg
    13141 ccgggcctcc tcctggacaa cgatgcgggg aaacatcatt ccccctcccc acatgccacc
    13201 cccgacagag agtttcttct cgatgatgcc gacgcggtgt cccctttccg cgaggagggc
    13261 agctgccgtg agtcccgatg gcccggcgcc gacaacggcc acgtccatct ccatgaaatc
    13321 gaggaatttc tcgagatagg atgccacgat ggccctgctg atggttatct cgtcaagttc
    13381 catggtgtcg tctttccttg aacggtcttg gcactcatcc gtccgggaaa cccgggtttt
    13441 ttgggggtca gaatgccgct ggaagaatat ttatagattt tgcagggcaa ataagttact
    13501 tatgaaagta tggaaacgcg atctcgg
//
LOCUS       DAOOJU010000038        11742 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5021_length_11742_cov_9.530846, whole genome shotgun sequence.
ACCESSION   DAOOJU010000038 DAOOJU010000000
VERSION     DAOOJU010000038.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 11742)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11742)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11742
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5021_length_11742_cov_9.530846"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..456
                     /locus_tag="PK679_08180"
     CDS             <1..456
                     /locus_tag="PK679_08180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004040768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HPC55967.1"
                     /translation="KGNTIPFIIFTGRGREEVAAEADRGNVRLINNIPEKTEIFADPL
                     IRRVWFNLVDNSLRHGGKVTAIRFSVEEKEDGLSIVCEDDGTGIPPGEKEKIFERGYG
                     KNTGMGLFLSREILAITGISITGNGEPGKGARFEIRVPPGKFRKGSAGP"
     gene            545..1894
                     /locus_tag="PK679_08185"
     CDS             545..1894
                     /locus_tag="PK679_08185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004078957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC55968.1"
                     /translation="MIREFVDRESELRLLEEEWEKPGGRLIILYGRRRIGKTRLIGEF
                     TRDKPGVLYFAEDTSPSLQMRQLQAACAAFLNDSLLASLEINSWEQLFTYLARHPPAG
                     RGYLVIDEFTYLVRNDPTILSALQKTWDTDLAGSPWCILLCGSMLGLMSDLALSSTSP
                     IYGRRTRDMLLEALQFSDARKFLSVPPLDALRIYLSIGGVPEYLLKAGDYETFSGFTT
                     REFFDRYGYFYREPYFILSQEFRELKMYQSILQAIAYGNTTPASIAQFCGLDSRHLYP
                     YLESMTRLGIIERELPVLVNTKKGVYRIKDRLFDFWYTFVFPNRQSIELNQVSIPDAH
                     FDPYFGRQFEIFIRHEVIPKLFPGFTIGRWWYGEEEIDIVGYDDHSATIIFGECKWGV
                     LTRKESQKILASLKEKSSHVRHARYTNEKFLLVARTIEDKEALRREGYLILDLDDVL"
     gene            complement(2642..3352)
                     /locus_tag="PK679_08190"
     CDS             complement(2642..3352)
                     /locus_tag="PK679_08190"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HPC55969.1"
                     /translation="MQEPLGTPDSPITAVLFDMDNTLFDFVGATIAACNAVNRRLGLD
                     RGQDLLFSFLRHDGRDFEDVRHIRDFMVDNAVFSEDLFAECCIIYEEAKIRNLTPYPH
                     SRETLQELREQGFFLSVVTDASFENAVIRLEKTGLFPLFDEVITAGMTGTHKPDPGVF
                     LCALEKMKRHPSEVLMVGDSLRRDIGPAKRLGMVTAYAKYGDRNFFEDREEKADITLA
                     DIRDVLAVVKKGKTGARD"
     gene            complement(3316..4326)
                     /locus_tag="PK679_08195"
     CDS             complement(3316..4326)
                     /locus_tag="PK679_08195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55970.1"
                     /translation="MADDAIIGIPGIQVLLNLLKSPVVVKYPLYDFDILTLRDTASGF
                     ILSGMCTREDFDEAIAAFGEFAYDMPSYNDVLQSMLAAGIVSYRNMEKFLEVRKSIPL
                     LNKEVLFSLDTNMLYHAFPSRGGIPGDRYILVDIVQSEIESALNTKYAAQTISQMKRM
                     APFEGALLEELINQKTKRSRIAAYNALAEFEKIRDQARIIPGIEPGGPDKEKNDLLIV
                     KSVREHEKDAFCTTLHLTADTNVAELCRAEGLAYHLFELPHAIDVRECTPAGAVDLLF
                     RLAVAFGVVKCGPAFIFGEYRGKGTKKQSLKVVIRNHNLEEEFKKELALCRSLSALPI
                     PR"
     gene            complement(4316..4813)
                     /locus_tag="PK679_08200"
     CDS             complement(4316..4813)
                     /locus_tag="PK679_08200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55971.1"
                     /translation="MSSERVYVSLLGRSAWALLNTYYAVAREVRYFPDRVYIAVEAPY
                     QNQTDHVVEGLHAISAHFGFSPEVECIPVARGDMIDVYLKVYNLITAKRKEGCRVAID
                     ITPGRKSTVSGVLLPIKLNDVDHVFYLEISTTDGVAKPYQMIPKQYHKLHDFKAEAVR
                     AGNGG"
     gene            complement(4860..6662)
                     /locus_tag="PK679_08205"
     CDS             complement(4860..6662)
                     /locus_tag="PK679_08205"
                     /inference="COORDINATES: protein motif:HMM:NF017519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC55972.1"
                     /translation="MAGGRLDLVEIDWGDGSRNNTFMDPKDIEQTTHIYNKPRNYTVT
                     ITGYRWDHQGNREIYVGNYHFNLSLLKGDIIVHAIDKDSPYSSTLSPYVPGHWTHAAM
                     YVGDDQVIESGWNSVRLSPVSEFVYPADECVAIFRVPDLTDTQRENIVNWAKEKLDDG
                     YDLQSLLGFFSGKQQDNDDYPCWTELPWVASYIRCKWACSHYYCSELVWAAYRRNGID
                     FDPERGCVYPMDLVLSKHVQVQLVGTHIEKIPKRDKAYSTTDRYYMLLLNSDVGDVVK
                     DIEKSGTCESCVGAMGTVADGNNDKKEGAGTPSARDLFDIRIKDPDGRFMTETDTMIP
                     SSTAAELDIDGDNILEMMNSIENADEGEYLITVSPECRDPDNYVFSLRIGAWDNDQIS
                     WIQPVTFTGLRSLPDEGKVRMRIEENGYCRMIGIPVRGTAPLNVSFMDISPLMRSSEE
                     WDYDDMVIDNTWDFGDGTSTSNTVTATHLYTQPGSYTVRLTTRNATMEATATMKVTVD
                     APEQSLSAGFTASPLSGTSPLTVQFTDASTGNPIVHIYKFGDGALGNGKNPVHTYRKP
                     GTYTVTLTVLGNDDAGRIQRNTTIKKDFIIVVSQ"
     gene            complement(7095..7179)
                     /locus_tag="PK679_08210"
     tRNA            complement(7095..7179)
                     /locus_tag="PK679_08210"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7141..7143),aa:Leu,seq:taa)
     gene            complement(7313..7900)
                     /locus_tag="PK679_08215"
     CDS             complement(7313..7900)
                     /locus_tag="PK679_08215"
                     /inference="COORDINATES: protein motif:HMM:NF015674.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HPC55973.1"
                     /translation="MVVCSFSSPARSWPSFLAGGILAVFLGLLLFLEPALSLRLMLYS
                     LGALAVIVGIIFLAAAVFLSRGGGWPFGVTLVFGLLMLGIAFIAFSNPGLLGGVLATL
                     AGAVLVVGGLAIAVSGAFSLPSFARKLGQVAGGGVLLATGLLLVFRSGLAATLIARAI
                     GILVLVFGVILLALAVLGWLKDRRSPPDWTDVCVR"
     gene            7909..9087
                     /locus_tag="PK679_08220"
     CDS             7909..9087
                     /locus_tag="PK679_08220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55974.1"
                     /translation="MGRRRSKIPVIPAAPDPAANKLNRLAPTTLTTREGTIRMYAIRF
                     YRIFDIGEEIDLEKLEQSLAASMATSRFRFQRVRPTSIIVDQPPLLIRLQGMTIDTVR
                     GPLSLAAMARIYEFGAFSICLRLEEMEAPARMLHEVALSFAGQEGLSRYFDQALAELR
                     SILAVHLGTRPLDPDFYDDYTIYLADRQDPGIDPVAVLLGEEAEFSPEIRKETLQYSF
                     SYYPDEKAILSWGGAVIFSPKPPVDLLELIEFAAVQVLELRFYDRELTRQMDRMYDDI
                     ENADRQWWIYRAVHYRKLMKQLMGEQAEVSEIVEDINNLIKVTDDIYYARVYAAALQA
                     LRSGSWSQSVNHKLATIRETYRMLSEEVNVQHAHFLEWIVIVLIALEIVLFTLPLVPH
                     "
     assembly_gap    9179..9278
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            9336..9653
                     /locus_tag="PK679_08225"
     CDS             9336..9653
                     /locus_tag="PK679_08225"
                     /inference="COORDINATES: protein motif:HMM:NF020549.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1894 domain-containing protein"
                     /protein_id="HPC55975.1"
                     /translation="MVPQPRCINKIRGKVILKDTTKDAVAAYVRENCSEYYDAPPGFS
                     FRGITLLLGEPMPLGLKRKKKKILVPFVKPCFGPMLVEVDAREEDFEYLAENLGGGRG
                     KGT"
     gene            complement(9753..10328)
                     /locus_tag="PK679_08230"
     CDS             complement(9753..10328)
                     /locus_tag="PK679_08230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HPC55976.1"
                     /translation="MRVVAFNGSPRKGGNTERLLNRVLSILDGEGIQTELVHIGGEKV
                     HGCTACGKCFANQDGRCVFDDDIINECIGKMAAADGIVIGSPTYFADVSPETKALIDR
                     AGFVAMANGRMFSRKVGAAVVAVRRAGGIHVFDTINHFFGISNMFTVGSIYWNIGFGL
                     NPGDVEQDDEGMMTMEALGRNMAWIIRKIKA"
     gene            complement(10407..10946)
                     /locus_tag="PK679_08235"
     CDS             complement(10407..10946)
                     /locus_tag="PK679_08235"
                     /inference="COORDINATES: protein motif:HMM:NF015317.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqhA family protein"
                     /protein_id="HPC55977.1"
                     /translation="MVHESGEGVAPRQEADGTCGQAPGKGTFLVGRLSRIIFLLSVTG
                     TFLLSISLFVYGFTITLTSLLYAYTHFTLHIDAMKEAMAIAVEIVDLFLVATVFYIIA
                     LGLYELFIAKAPLPGWLKICNLDDLKEKLLGLIVIALGVLFLGESLVWPNGIGDLLVY
                     GVANAAVIAAISLYVWIKH"
     gene            complement(11110..11592)
                     /locus_tag="PK679_08240"
     CDS             complement(11110..11592)
                     /locus_tag="PK679_08240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC55978.1"
                     /translation="MSFFCQQCGECCSVMGQVFSIREERGAFRFLFENLYTGEETEVE
                     VSPPWRELFSTGKNPSGWLNPCPFLRYDPAGGKAVCTVHATRPATCRDYGCWRVLVLD
                     PSGFRVARVMEKRYLHLAEPSLEREWEEFRDTIDHLPDDAWDSAVARFFRQRGYSVFR
                     "
BASE COUNT         2490 a         3332 c         3366 g         2454 t
ORIGIN      
        1 aaggggaaca cgatcccctt catcatcttc accgggagag gccgcgagga ggtcgcggcg
       61 gaggccgatc gcggcaacgt ccgcctgatc aataacatcc cggagaagac ggagatcttt
      121 gccgatccgc tgatccgcag ggtatggttc aacctcgtgg acaattccct ccggcacggc
      181 gggaaggtaa cggctatccg gttctctgtg gaagaaaagg aagacggtct ttccatcgtg
      241 tgcgaggacg acgggacagg catccccccc ggagagaaag aaaagatatt tgaacgggga
      301 tacgggaaaa acacgggcat gggcctcttt ttgtcccgcg agatcctcgc gatcaccggg
      361 atttcgatca ccgggaacgg cgagccgggg aagggggcac ggttcgagat cagggtgccg
      421 cccggaaagt tcaggaaagg atcggcgggt ccgtgaacgg ggggccgtgc ctgctttttg
      481 ggggtcgcgg gatttttgga aatcataaat gctaatatac ccctaatcct gattagtact
      541 aatcatgatt agggagtttg tggaccggga gagtgagctc agacttctgg aggaggagtg
      601 ggagaaaccc ggcggccggt tgatcatcct ctatggccgg aggagaatcg gaaagacccg
      661 gctgatcgga gagtttacca gagacaaacc gggtgtcctc tattttgccg aagatacgtc
      721 cccgtcatta cagatgcgtc agctccaggc ggcctgcgca gcattcctca atgattcgct
      781 cctggcatcc ctggaaatca attcatggga acagctcttc acgtaccttg ccagacatcc
      841 ccctgccggc aggggatatc tcgtgatcga tgaattcacc tacctcgtca ggaatgatcc
      901 cacgatcctt tctgcactgc aaaagacctg ggacacggac ctggccgggt ctccctggtg
      961 cattctcctc tgcggatcga tgctcgggct catgagtgat cttgcactct cctcgacatc
     1021 cccaatctac ggacgaagaa cccgcgatat gctccttgag gcgctccagt tctccgatgc
     1081 ccgaaagttc ctgtccgtcc cgcccctcga tgcactcagg atttatcttt ccattggtgg
     1141 agttcccgaa tatcttctga aagccgggga ctacgagact ttttccggtt ttactacccg
     1201 ggaatttttt gaccgttacg ggtattttta ccgggagccg tacttcatcc tctcgcagga
     1261 gttccgggag ctgaagatgt atcagtcaat cctgcaggcg atagcatacg gaaacaccac
     1321 gccggcatcc atcgctcagt tctgtggact tgactcccgc catctctatc cctacctgga
     1381 aagcatgacc cgtctcggga tcatcgagcg ggagcttcca gtcctggtga acacaaagaa
     1441 gggggtctat cggatcaaag accgcctttt cgacttctgg tataccttcg tctttcccaa
     1501 ccggcagtct atcgagctca accaggtctc aatcccggat gcacattttg acccatactt
     1561 tgggcgacag tttgagatat tcatccggca cgaagtgata ccgaaactgt ttcctggctt
     1621 tacgattgga cgatggtggt atggtgagga agagatcgat atcgtcggat acgatgacca
     1681 ttctgcaact atcattttcg gggagtgcaa atggggtgtc ctgacccgga aggaatcgca
     1741 gaagatcctg gcatccctta aggagaaatc atcacatgtc cggcatgccc gatatacgaa
     1801 tgaaaaattt ctgctcgttg ccagaacgat cgaggataaa gaggcactcc gaagagaagg
     1861 gtacctgatc cttgatcttg atgatgtatt gtaagtctga aacaacattc catcatgacc
     1921 ctggccacac cggagcggag gggtgtttcc ctggtgtgat ccggactctc ccctcacggc
     1981 tgggatgctc tatgattcgg cacagatgag gatgcggatc agctatatgg ccattccacg
     2041 agagaatcaa aacattggac gacctgcggc tgatcaatgc caaacacaag aaccagggga
     2101 ttggcggcaa gacgagggaa tccatgctcc ggtatgaccc ggtcagggtg atggaggcgg
     2161 ggggatgaaa tgaaattggt gattccctca taaaggccac aattatatac taacaaatgg
     2221 tggcaagatg aataaacctg gtagaactca cccgatacac gaatgacgag gagggttcag
     2281 aggcattttt aagttcacac gggattctca agacattcgg ggaatgcccg tactgtggga
     2341 gcaggaggtt caatagagtc aggatacagg tacgaggctt attttaagca atcatctgaa
     2401 tttttttcat gcccttcttt ttatgggaac ttttgaagaa cagagaatgc gaggggtggg
     2461 attcgaaccc acggactcct tcgggacggg ctctcaagga tccattattc atcacctgct
     2521 gttcggaaat atctgctgcg ccgcaggagg ccgctccccc ggcaaatcct tttcccatgg
     2581 attccttcat ggagaaacgc agtgttacag gacggggaca accgaccctg ccttctctcc
     2641 ttcaatcccg ggcaccagtt ttaccttttt tcaccacagc cagcacatcc cggatatccg
     2701 cgagcgtgat atcagccttc tcttcacggt cttcgaaaaa gttccgatct ccgtattttg
     2761 catatgcggt caccatcccg agtctcttcg caggcccgat atcccggcgg agactgtccc
     2821 ctaccatcag gacctcggac gggtgacgct tcatcttttc gagtgcacat aaaaataccc
     2881 ccgggtccgg tttatgggta ccggtcatcc cggccgtgat gacctcgtcg aagaggggga
     2941 acagtccggt cttttccagc cggataactg cgttctcaaa ggaggcatcg gtcacaacgg
     3001 acaggaaaaa gccctgctcc ctgagttcct gaagcgtctc cctgctgtgc gggtagggag
     3061 tgaggttccg gatcttggcc tcctcataga taatgcagca ctcggcgaac agatcctcgg
     3121 aaaacaccgc gttgtccacc atgaagtccc ggatatgcct cacatcctca aaatccctgc
     3181 cgtcgtgccg caggaaagag aagaggaggt cctgcccccg gtcgaggccg agcctccggt
     3241 tcactgcgtt gcaggccgcg atcgtggccc cgacaaagtc aaagagggtg ttgtccatgt
     3301 cgaagaggac cgcggttatc ggggaatcgg gagtgccgag aggctcctgc ataaagcgag
     3361 ttcctttttg aattcttctt ccaggttgtg atttctgatg accaccttga ggctctgttt
     3421 cttcgttcct tttccgcgat attcaccgaa tataaaggca gggccgcact taacgacacc
     3481 gaaggcaacc gcgaggcgga agaggagatc cactgccccc gctggcgtgc attccctgac
     3541 atcgatcgca tggggaagct caaagaggtg gtaggccagc ccttctgccc tgcagagctc
     3601 cgcgacgttt gtgtcggcgg taaggtggag ggtggtgcaa aacgcgtcct tctcgtgctc
     3661 cctcactgat ttcacgatga ggaggtcgtt tttctccttg tccggtccgc ccggttctat
     3721 gccgggtatg atccgcgcct ggtcccgtat cttctcgaat tccgcgaggg cgttatatgc
     3781 cgcgatccgg gaccgctttg tcttctggtt gatgagttcc tcgagcaggg caccctcaaa
     3841 gggagccatc cgcttcatct gggagatcgt ctgggctgca tacttcgtgt tcagggcact
     3901 ctcgatctca ctttggacga tgtcgacgag gatatagcgg tctccgggaa tgcctccccg
     3961 tgaggggaat gcatggtaga gcatgttggt atccagggag aagagcacct ccttgttgag
     4021 gagcggaata ctcttcctga cctccaggaa tttttccatg ttccggtagg agactatccc
     4081 ggcagcgagc attgactgca gcacgtcgtt gtatgacggc atatcatacg caaactctcc
     4141 gaatgccgcg atggcttcat caaagtcttc ccgtgtgcac atgccggaca ggataaagcc
     4201 ggacgcggta tcccgcagcg tcaggatgtc gaagtcgtac aggggatact ttaccactac
     4261 cgggctcttc aggaggttca ggaggacctg aatcccggga atcccgatga ttgcgtcatc
     4321 cgccattgcc ggccctcact gcttctgcct tgaaatcatg gagcttgtgg tactgtttcg
     4381 ggatcatctg gtatggcttt gccactccat cagtggtgga aatctcaagg taaaagacgt
     4441 gatcaacatc gttgagcttt atcgggagga gaacgcccga aaccgtcgac ttcctgccgg
     4501 gggtgatgtc gattgcgacc cggcatcctt cctttctttt tgccgtgatg aggttgtaca
     4561 ccttgagata cacgtcgatc atgtctcccc gggccacggg gatgcactcg acctctggcg
     4621 agaacccgaa gtgggcggag attgcatgca ggccttccac cacgtggtcc gtttggttct
     4681 ggtaaggagc ctcgaccgcg atgtacaccc tgtccggaaa atagcgcacc tcacgggcta
     4741 cagcgtaata cgtgttgagg agtgcccatg ccgaccggcc gagcaggctc acgtaaacac
     4801 gttcagaact catagcgctc gcttttttgg cagggggatg gtggcctgaa aaagagagat
     4861 cattgggaca ccacaatgat gaagtccttt ttgatcgtgg tgttgcgttg gatccgccct
     4921 gcatcatcat tccccaagac ggtcagcgtt accgtatagg tgccgggctt ccggtaggta
     4981 tgcacggggt tcttcccgtt acctaacgcc ccgtcgccga atttatagat atgcacaatg
     5041 gggttcccgg tggaggcatc ggtaaactgc acggtgagag gactggttcc ggagaggggg
     5101 gaggcagtaa atcctgcgga aagggactgc tcgggggcat cgacggttac cttcatcgtt
     5161 gcagtcgctt ccattgtcgc gttccgggtg gtaagccgga ccgtgtaact gccgggttgg
     5221 gtatacaggt gggtggccgt gacggtattc gaagtagaag tcccgtcccc gaagtcccag
     5281 gtgttgtcga tcaccatatc gtcataatcc cattcttcgc tgctccgcat caggggcgag
     5341 atatccatga acgagacatt gagcggggcg gtgccccgta cgggtatccc aatcatccgg
     5401 cagtacccgt tctcctcgat ccgcatccgg acctttccct cgtccgggag cgaccggagc
     5461 ccggtgaagg tgaccggctg aatccaggag atctggtcgt tgtcccacgc cccgatccgg
     5521 agtgaaaaaa cgtaattatc cggatccctg cattcaggag atactgtgat caggtattcc
     5581 ccttcatcag cgttttcgat gctgttcatc atctccagga tattatcccc gtcgatatcc
     5641 agttctgcgg ccgtggacga gggtatcatc gtatccgttt cggtcatgaa ccgtccatcg
     5701 gggtccttga tccggatatc gaacaaatcc cttgcagagg gggtcccggc accctctttt
     5761 ttgtcattgt tcccgtccgc cacggttccc attgcaccga cacaggactc gcacgtgccg
     5821 gatttctcaa tgtcctttac cacgtccccc acatcggagt ttaacaggag catgtagtac
     5881 cggtccgtgg tgctgtaggc tttgtcacgt ttcgggatct tctcgatatg agtaccgacc
     5941 agctggactt gcacgtgctt gctcagtaca aggtccatcg ggtacacgca tcccctttcc
     6001 gggtcgaaat cgatcccgtt cctccggtag gccgcccaca cgagctcact gcagtagtaa
     6061 tgcgaacagg cccatttgca gcgtatatag gaggccaccc aagggagttc cgtccagcac
     6121 gggtaatcgt cgttatcctg ctgtttcccg gagaagaagc ccagcaggga ctgaaggtca
     6181 tacccgtcat ccagtttctc tttcgcccag ttgacgatat tctcccgttg ggtatccgta
     6241 aggtccggaa ccctgaaaat cgccacgcac tcgtccgccg ggtagacaaa ctcgctcacc
     6301 ggactgaggc ggacgctgtt ccaccctgat tctatgacct ggtcatcccc cacatacatt
     6361 gcggcatgag tccagtgccc gggaacatag ggggataatg ttgatgaata cggagaatct
     6421 ttatcgatcg cgtgcacaat gatgtcccct ttcaggagcg agaggttgaa atgataattc
     6481 ccgacataga tctcgcggtt cccctggtga tcccaacggt acccggtgat tgtgaccgtg
     6541 tagttccggg gtttattata gatatgggtc gtttgctcga tgtccttcgg atccatgaat
     6601 gtattgttcc tgctcccgtc gccccagtcg atttcaacca ggtcgaggcg ccctccggcc
     6661 acggttcctt caagtctgca gtgtaacctc ccgccaaagc agggtgcttg gtcataacac
     6721 cggaaccctg tataagggta taccattttg gcagaactcc ccttcgtacc attacccccg
     6781 gtatccgcca ttgctgcggg gacccctacc agcagcagga ccaggaggat ggtcaggaga
     6841 attccgatgc gatatgtatg agagggtgtg cagggtcctg gttccggttt catgcatagt
     6901 gatacttgta aactgttata ataacccacc cttctggtga acatgctcaa acgacaaaaa
     6961 acctttcgga attttgaaaa cacccgggtg acaggagggg gagttacttt tcaatgtatc
     7021 aaaagagtgt cccgttcaca atcaggccag gtgctgcatc tctgagttcc attaatgaaa
     7081 attgttgaaa agaatgcgag gggtgggatt cgaacccacg gactccttcg agaacggatc
     7141 ttaagtccgc cggttttggc caggcttgcc taccctcgca ggacttcttt tcccaataat
     7201 ctggtgccac cggacaataa ggccgtcggt gtgcaaaagg ccggaacgct ggcatacgtc
     7261 ccctgcctgc cgggacggga tggcagaaaa aaagggagga cccgcaatcc cctcaccgga
     7321 cgcacacgtc cgtccagtcc gggggagacc ggcggtcttt cagccagccg aggactgcaa
     7381 gggcgaggag gatgaccccg aaaacgagga cgaggatgcc gatggcccgg gcgatcaggg
     7441 tcgcagcaag gcccgagcgg aagacgagca ggagaccggt ggcgagaagg acgccccctc
     7501 cggcgacctg ccccagtttc cgtgcgaacg acgggaggga gaatgccccg gatacggcga
     7561 tggcaaggcc cccgacgacg agaacggccc cggcaagggt ggccaggacg cccccgagga
     7621 gaccgggatt ggaaaacgcg atgaaggcga tgccgagcat caggagaccg aaaacgagcg
     7681 tgaccccaaa cggccacccg cctccccggg agaggaagac ggcagcggca agaaagatga
     7741 tcccgacgat caccgcgagg gcgcctaagg aatagagcat caggcggagg gagagggcgg
     7801 gctcgaggaa gagcaggagc ccgaggaaca cggcgaggat gccgcccgca aggaacgatg
     7861 gccacgaccg ggccggagag gagaaggaac agaccaccat gacagatcat ggggcgccgg
     7921 cggtcaaaaa tcccggtgat cccggccgca cctgatcccg ctgcgaataa gcttaatcgt
     7981 ctcgccccga ccacactcac cacgcgggag gggacaatcc ggatgtatgc aatccgtttc
     8041 taccggatat ttgacatcgg ggaggagatc gacctcgaaa agctcgagca gagccttgcg
     8101 gccagcatgg caacgtcccg gttccggttc cagagggtcc ggccgacctc gatcatcgtc
     8161 gaccagcccc cgctcctcat ccgcctgcag ggcatgacga tcgacacggt acggggcccc
     8221 ctctccctcg cggcaatggc ccgcatctac gagttcggtg cattctcgat atgcctgcgc
     8281 ctcgaggaga tggaggcacc cgcacgcatg ctccatgagg tcgccctctc ctttgcaggc
     8341 caggaggggc tctcccggta cttcgaccag gccctcgccg agctccggtc gatccttgcc
     8401 gtccatttgg ggacccgccc cctcgacccg gacttctacg atgactacac catctacctt
     8461 gccgaccggc aggaccccgg catcgacccg gtggcagtcc tgctcgggga ggaggcagag
     8521 ttctcgccag agatccggaa ggagacgctc cagtactcgt tctcgtacta ccccgacgaa
     8581 aaggcgatcc tctcgtgggg tggtgcggtc atcttttcgc ccaagcctcc cgtcgacctg
     8641 ctggaactga tcgagtttgc ggcagtccag gtcctcgagc tccggttcta cgaccgggaa
     8701 ctgacccgcc agatggaccg gatgtacgac gatatcgaga acgccgaccg ccagtggtgg
     8761 atctaccggg cggtccacta ccgcaagctg atgaagcagc tcatgggaga gcaggccgag
     8821 gtctccgaga tcgtcgagga cattaacaac ttaatcaagg tgacggatga catctactac
     8881 gcccgggtct atgccgccgc actccaggcc ctgcgcagcg ggtcgtggag ccagagcgtc
     8941 aaccacaagc tcgcgaccat ccgcgagacc taccggatgc tctccgagga ggtcaacgtc
     9001 cagcacgccc acttcctcga gtggatcgtc atcgtcctca tcgcgctcga gatcgtgctc
     9061 ttcacgctcc ccctcgtccc ccactgacct gaccccgtgt gacggcaacc ggctgggacg
     9121 ggaaccggtg gaaccgtcgt ggcctatccg gagcatccgt ccggcaagcg ggaaggggnn
     9181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnac cggactttcc acgatcgtat
     9301 tcatttaagg gatgctgcgt cccagtacat cgaccatggt cccgcagcca cgctgcatca
     9361 ataagatccg gggaaaagtc atcctcaagg acacgacaaa ggacgctgtc gctgcttacg
     9421 tgagggagaa ctgctcggaa tactatgacg ccccgcccgg cttttccttc cggggcatca
     9481 ccctcctcct cggcgaaccc atgccgctcg ggctcaagag gaagaaaaag aagatcctcg
     9541 tcccgttcgt caagccctgt tttggaccca tgctggtcga ggtcgatgcc cgggaggagg
     9601 atttcgaata ccttgcagag aacctcggcg gcggcagggg aaagggaacc tgactcccct
     9661 ttgccgtgcc ggggtggatg ccttctccct cgtttttcac ccggcgggaa aaggagcccc
     9721 gcacgtatct gcctgtggcc tctttcttcc cgtcaggctt tgatcttcct gatgatccag
     9781 gccatgttcc gcccgagcgc ctccatggtc atcatcccct cgtcgtcctg ttccacgtca
     9841 cccgggttga gcccaaaccc gatgttccag tagatggacc cgacggtgaa catgttgctg
     9901 atgccaaaga agtggttgat ggtatcgaac acgtggatgc cccccgcccg gcggacggcc
     9961 accaccgcgg cccccacctt gcgggaaaac atcctcccgt ttgccatcgc gacgaatccg
    10021 gcccggtcga tgagggcttt tgtctccggg gagacatcgg caaagtaggt cggggacccg
    10081 atcacgatcc cgtcggcggc agccatcttt ccgatgcact cgttgatgat gtcgtcgtca
    10141 aagacgcacc gcccgtcctg gtttgcaaag cacttcccgc aggcggtgca cccgtggacc
    10201 ttctccccgc cgatgtgaac aagttcggtc tgtatgccct ccccgtcgag gatggaaagc
    10261 acgcggttca acagccgttc cgtgttcccg cctttccgcg ggctcccgtt gaatgcaacg
    10321 actcgcatga tcagagtggt ggaaccggta tatgataaaa ggcatccccc tgcccgcgga
    10381 gaaaaggggg ggggagggag gaattcttag tgttttatcc agacgtacag ggatatggca
    10441 gcgatgacgg cggcgttggc aacgccgtag acgaggaggt caccgatacc gttcggccac
    10501 accagcgatt cgcccaggaa gagcaccccg agcgcgatca cgatgagacc gaggagtttc
    10561 tccttgaggt catcgaggtt gcagatcttg agccagccgg ggaggggggc cttggcgatg
    10621 aagagctcgt agagcccgag ggcgatgatg tagaagaccg ttgcaacgag gaagaggtcc
    10681 acgatctcga cggcaatcgc catcgcctcc ttcatggcat cgatgtggag ggtgaaatgc
    10741 gtgtatgcgt agaggaggct ggtgagggtg atggtaaagc cgtacacgaa gagtgaaatg
    10801 gaaaggagga atgtgccggt cactgaaagg agaaagatga tcctgcttag gcgcccgacg
    10861 aggaacgtcc ctttcccggg ggcctgcccg cacgtgccgt ctgcctcctg ccggggcgcg
    10921 actccttccc ctgactcgtg taccattatg tcttctgcct cctcttcctt ggtaaggatc
    10981 gcaccttttc ctacataaaa cggcacggta tcagccggga aagacggcgg cggtcgggag
    11041 ggacacaccg ggtcccggat cgccccggca aaaaggttgt ctcctgccgg agaacccggt
    11101 ttttccggct caccggaaaa cggaataccc cctctggcgg aagaaccgtg cgacggcact
    11161 gtcccacgcg tcgtcgggaa ggtggtctat tgtgtcccgg aactcttccc attcccgttc
    11221 aagcgacggt tccgcgaggt ggaggtaccg cttctccatg acgcgggcaa ccctgaagcc
    11281 ggaaggatcg aggacgagga ccctccagca cccgtaatcc ctgcaggtcg ccggtcgcgt
    11341 cgcgtggact gtgcacacgg cctttccgcc cgccggatcg tagcggagga agggacaggg
    11401 gttcagccag ccggaggggt tctttccggt ggaaaagagc tcgcgccagg gtggggagac
    11461 ctcgacctcc gtctcctcgc cggtatagag gttctcgaac aggaaccgga aagcgccccg
    11521 ctcttcccgg atggaaaaga cctgtcccat gacgctgcag cattccccgc actgctggca
    11581 gaagaacgac atcggaggta cctcgacgtt cttttgataa ggacgtttgg gtcgggatgc
    11641 cggcacccgt atttccgttc ggcgggcggg tcttatgcca tgaaaaagct ggagagacca
    11701 cggaaaggcc ggctcctggg cggcgtgtgc gcgggtatcg gg
//
LOCUS       DAOOJU010000039        11364 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5208_length_11364_cov_16.916261, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000039 DAOOJU010000000
VERSION     DAOOJU010000039.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 11364)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11364)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11364
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5208_length_11364_cov_16.916261"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(430..1545)
                     /locus_tag="PK679_08245"
     CDS             complement(430..1545)
                     /locus_tag="PK679_08245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0042398 - cellular modified amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-cysteine ligase family protein"
                     /protein_id="HPC55979.1"
                     /translation="MKTGTEHEFSINSRELVPLPCSDLILTETGGSPDCEVPLAGATI
                     GKELQKTVLEFVPLHPSHRLSVLESLVQSGIAEFYRRFSDRYVLLGLGMHPVLSPGES
                     VVWDHGESAIYREYDRLFSLKQHGWVNVQAFQVNFEYRDDDHLVRMFNRARSLIPYLV
                     AVSAASPFVEGRLSGTLDSRLISYRENQARIPAICDGIVPRPIGSVADYRERLSAIYG
                     LLRQQGADILCEEWVASFGVIVRFSRPCIEIKVIDEQECVFSDMALCAFARALMRADA
                     PPLEDDQRSLLAMTEDAIRTGTAGLEEELSHLFRHAVDAATPEEKHYLSLVRARIEEG
                     CLASVLADRFRERGDLEEIMRDLALCLKENRPFMAGE"
     gene            complement(1542..2045)
                     /locus_tag="PK679_08250"
     CDS             complement(1542..2045)
                     /locus_tag="PK679_08250"
                     /inference="COORDINATES: protein motif:HMM:NF015639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC55980.1"
                     /translation="MNPEFEKTASAICARCGATCCHEARPPLSPGRVALLLANGVSPG
                     DIEYAGYHRIRTRENGMCVMCSGGKCRIHSFKPETCRAGPFTFDVEGETVRIFLKHDS
                     LCPLVAFLKADPAMYAVQFRVAVNNILSLARSLEPDELAVISAIPEPDCDLVAEIPLF
                     PGNPGGP"
     gene            complement(2063..2932)
                     /locus_tag="PK679_08255"
     CDS             complement(2063..2932)
                     /locus_tag="PK679_08255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RimK family alpha-L-glutamate ligase"
                     /protein_id="HPC55981.1"
                     /translation="MSRLGIFVDRRTLSSSDQLTSLIRCRDAAEEMGHSVEFIFPVDI
                     RKIPQMDALFIRARTDPMNITYVASRMAAFAGIPVIDDPESIQVCSDKVNMYMHLARA
                     GVAIPRTLFLSKGDIHPSRVRDIMDDLGTPLVLKEPSTSFSLRVERVEDPAAFIRVAR
                     RYLKMSDWVVAQEYVQSTYDWRIGVLRGRFLYACKYIIPSQTFKIQDSVNGHVVYCAV
                     ESVPPDAVPAPIRDLGVAAGKAIGDGLYGVDIKDGKEPKVIEVNDNPSLEGGEDGSYP
                     HVYREIVHALLET"
     gene            complement(2929..3639)
                     /locus_tag="PK679_08260"
     CDS             complement(2929..3639)
                     /locus_tag="PK679_08260"
                     /inference="COORDINATES: protein motif:HMM:NF025759.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RimK-like ATPgrasp N-terminal domain-containing
                     protein"
                     /protein_id="HPC55982.1"
                     /translation="MNGVSPGIATPAEQQGGVPAAAVNRRGFHLARDRVYTVRYGGYT
                     TFVSENYSYKSETYYAILARELAGEAVAPDTQSMLDAFVVPVCLERAGHCGIPVAAYT
                     IMHSCAPAPAIVYGLNYFASTSHFEVLTGDARDREKVRHVTNGGKYPCCSQPISPDMA
                     VTRAVSVFGKVLSPVPGMQEMAGSVWECFRIPLVELVCLSGPGGPVLSSLCPVRYSRL
                     QPAERRLLKACIFGQVFL"
     gene            complement(4006..4662)
                     /gene="phoU"
                     /locus_tag="PK679_08265"
     CDS             complement(4006..4662)
                     /gene="phoU"
                     /locus_tag="PK679_08265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HPC55983.1"
                     /translation="MKDKFHDELARMRAGVLGMGFFAEQMLSDAMRALQENDTGLARE
                     VKERKVRLSGQNDTLEEDAYRLIALYQPVARDMREIACALKIISSAERIGRYGKDTAG
                     VVLSLGETRPDDLVNALSLPHMAKLVLSMIDDALHAYETGDLGLIAHHHERDDVVDKL
                     RHTIFREGITYMMEDPRTITRCTNYLMVARYLERCADHSCKIAEKVHYLVTGERIEIR
                     "
     gene            complement(4676..5437)
                     /gene="pstB"
                     /locus_tag="PK679_08270"
     CDS             complement(4676..5437)
                     /gene="pstB"
                     /locus_tag="PK679_08270"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HPC55984.1"
                     /translation="MSPDTIIATDRLNLWYGDTRALVDVSMEIPDRKVTALIGPSGCG
                     KSTLIRCFNRMNDILPGCRIEGKVMYHGENIYDNGSDPVSLRRRIGMVFQKPNPFPKS
                     IYENVAYGPRVHGIRDRRTLDSIVEESLRRAALWDEVRDRLSRSALSLSGGQQQRLCI
                     ARTLAVEPEVILMDEPCSALDPIATAKVEGLIDELKKQYCVIIVTHNMQQAARVSDYT
                     GFMYLGRLIEFGGTTQIFESPRDELTENYITGRFG"
     gene            complement(5442..7406)
                     /gene="pstC"
                     /locus_tag="PK679_08275"
     CDS             complement(5442..7406)
                     /gene="pstC"
                     /locus_tag="PK679_08275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HPC55985.1"
                     /translation="MTLPLPRQTKQGRLIPARTGETLIRLILLSCAGIAIVTIFFILA
                     FLIRDGYPVLSETGITSFLLGTEWNPTGYPVEKFGIVPLVAGTLCVTLGAMAIAVPLG
                     IACAICVARLAPPAVRAVVKPAIELLAGIPSVVYGFFGLIVLTDWIRATFGVPSGESW
                     LAGSIILGIMALPTIISVSEDALSCVPREFSEGSLALGATHWQTISRVIVPGALPGIS
                     AAVILGMGRAIGETMAVLMVTGNAAIVPSPLWNVLSPVRTLTGTLGIEMGEVATGSMH
                     YHALFGVAVVLLVITLAVNLVATTIIGRLREQYAPGRPCGNTVPGSRRASLLSPEMRE
                     RAKMVLLVAVLSLIGLPAAGIAGYAGCVFLFSLVALSWRRLSPRTTQKIAFFFISAAT
                     ATVLLILAVILSDILVKGLPALSFEFLTEPPRDLGRSGGIFPAIVGTLYLVAGAIGFA
                     LPLGIGAAIYLSEYRAEGRLTKIVRTGTELLNGTPSIVFGLFGFAFLVLFLKFGVSLI
                     AGQITLGLMILPTVIRTTEEALKGVPVSLREGSLALGATQWQTVSRVVIPPAVPGIVT
                     GAILSIGRAAGETAPILFTAVVFSQRFLPDSPFSPVMALPYHLYILATNIPGAEANKY
                     ATAVVLLLLVILFYAIAIGIRTHYQKNTHW"
     gene            complement(7443..8327)
                     /locus_tag="PK679_08280"
     CDS             complement(7443..8327)
                     /locus_tag="PK679_08280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HPC55986.1"
                     /translation="MNGMRNPASIATLLALILVMALLACGCTQQAGSQPPTTTSPGKT
                     RESITLSGSTTVLPVAQAAADAYMNTHANAEIMVIGGGSSVGIQAAGEGTASIGMSSR
                     DLKAEEKTRYPGLVSTVIGNDGIALIVHPSNTVGPLTLEQVKGIYQGKYTNWKDLGGP
                     DMAIVVAGRDSASGTREFFHEKVMNKEDFVAGQLEKNSNGAVKQTVAQTPGAIGYVGL
                     GYIDGTVRAVPILVNGTPIEPSVRTVLDRKYPISRPLILVTKGEPAGLAKDYITFLLG
                     PEGQKILEKEGFVPLGQA"
     gene            8491..8970
                     /locus_tag="PK679_08285"
     CDS             8491..8970
                     /locus_tag="PK679_08285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HPC55987.1"
                     /translation="MQGDRWGRVLPPGPSYKNGARDTDSREAPMGGDNLVEVTDSTFE
                     KTVEKSSLPVLVMFYSPTCVHCRAMEPHVREYAEVFAGRVLFARLDVIAGQWTAERYG
                     VRSTPTFKFFCSGRPISELVGAVYPALLKRMVEDGLQNGKECVTHSTAVNYDITGYA"
     gene            9113..10414
                     /locus_tag="PK679_08290"
     CDS             9113..10414
                     /locus_tag="PK679_08290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HPC55988.1"
                     /translation="MTTINRKALPLFCIILTAGLILGPVQAAEKYLGESPDLAVSIAG
                     ANEYYPGKEVTISVLVENRATPGTKIIAPGQDQWPDRPTTAKLVRVALLPGDAPVIIR
                     TDPQMIGDLPLGSSRSVPFQVKIPEGARGGTYTLPVDLQYTSISFAEQVGTDTQILHY
                     KDANITRSVEVKVRPRLVFTVTNVTGAEISSGQEGELAVTIRNNGTFKGRDATVRIIR
                     HDGSPVIPVEGSAYIGDFAPGDSFSTTFRVRVPDDAQGTTYPLDLVIRYRDDEDDLVD
                     SDRETIGVPVHGRAEFSIEPAEVTIPRGLSRDIALTIRNTGPVTLRSAQARVKVIEPF
                     SSSKYTAALGDLAPGEEATVTVSLAVDKSATRKVYGLDTEIQYRDALDNIVVTSPSTL
                     RIAVVDRNIIESVTTNPVSISIIVAVILGAVYFYYRRKKGE"
     gene            complement(10713..11168)
                     /locus_tag="PK679_08295"
     CDS             complement(10713..11168)
                     /locus_tag="PK679_08295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin family protein"
                     /protein_id="HPC55989.1"
                     /translation="MTPEDYKKIISNAINREVEAYTFYKTVSDKVKDANLKKLFNELA
                     GEETKHREFLQGLLSKDVKALKFSATKDYKVGDNIKTPDLKPDMKPVDGLVVAIKKEL
                     EAMQMYTALANNSEDAQQKKMFLELANMERGHKARLEDIYVNTAFAESW"
BASE COUNT         2228 a         3308 c         3574 g         2254 t
ORIGIN      
        1 ggatgatcgg gcactgtgtc atgtcctatt ccccagcact ggccctatcg ccacaggggg
       61 gtgccgcagc ggcggggcat cagccccaag agcgtcaaag gaggggagtg cggtctgtta
      121 tcgctccggt ttatcactcc ccggtgggaa tgggaatcgg gcagggttga ttgggcgtgg
      181 tgtcatgtcc tgttccccag cactggccct atcgccacag ggggggtgcc gcagcggcgg
      241 ggcatcagcc ccaagagcgt caaaggaggg gagtgcggtc tgttatcgct ccggtttatc
      301 actccccggt gggaatggga atcgggcagg gttgattggg cgtggtgtca tgtcctgttc
      361 cccagcactg gccctatcgc cacagggggg gtgccgcagc ggcggggcat cagcctcgga
      421 gacgacagat cattcccctg ccatgaacgg ccggttctcc ttcaggcaga gggcaaggtc
      481 acgcatgatt tcctcaagat cacctctctc ccggaaccgg tctgcaagaa ccgaggcgag
      541 gcacccctct tcgatcctcg ccctgacaag ggagaggtaa tgcttctctt cgggtgtggc
      601 agcatcgacc gcgtggcgga acaggtgcga gagttcctcc tcgaggcctg ccgtcccggt
      661 gcggatggca tcctcggtca ttgcgaggag cgacctttgg tcgtcctcga ggggaggggc
      721 gtcggcccgc atgagcgccc gggcaaaggc acacagggcc atatccgaaa agacgcattc
      781 ctgctcgtcg atgaccttga tctcgatgca ggggcggctg aaccggacga tgacgccgaa
      841 cgatgcaacc cattcctcgc agaggatatc cgccccctgc tgtcgcagga ggccgtagat
      901 ggcagagagc ctctcgcggt agtcggcaac ggatccaatg ggccggggga caatcccgtc
      961 gcatattgcg ggtatcctgg cctggttctc cctgtaggag atgagccggg agtcgagcgt
     1021 cccggaaagg cgcccttcga cgaaaggaga cgcggcagag acggcgacca ggtacgggat
     1081 gagcgagcgt gccctgttga acatccggac gaggtgatca tcgtccctgt attcgaagtt
     1141 gacctggaaa gcctggacgt tgacccaccc gtgctgcttg agggaaaaga gcctgtcgta
     1201 ttcccggtag atcgcggatt cgccatggtc ccagacgaca ctttctccgg gcgagagcac
     1261 cgggtgcatc ccgagcccga gcaggacgta ccggtcggag aaacgccggt agaattccgc
     1321 gattcctgat tggacgagcg attcgaggac ggagagcctg tgcgacgggt gcagggggac
     1381 gaactcgagc acggtcttct ggagctcctt cccgatcgtg gcaccggcca gggggacctc
     1441 gcaatcgggg ctccctccgg tctcggtgag gatcaggtcg gagcagggca ggggaacaag
     1501 ctccctgctg ttgatcgaga actcgtgttc ggttccggtt ttcatggtcc cccgggattg
     1561 cccggaaaga gggggatttc ggcaacgagg tcgcagtccg gttccggtat cgcgctgata
     1621 acggcaagct cgtccggttc aagggatcgc gcgagggaga ggatgttatt gactgcgacc
     1681 cggaactgca cggcatacat cgcggggtct gccttgagga aggcaacgag cgggcagagg
     1741 gagtcgtgct tgaggaaaat ccggacagtt tccccttcca catcgaaggt aaacggtcct
     1801 gcccggcatg tctccggctt gaaggaatgg atccggcact tccctcccga gcacatgacg
     1861 cacatcccgt tctcccgcgt ccgtatccgg tggtaccccg cgtactcgat gtctccaggc
     1921 gatactccgt ttgcgagcag gagtgccacc ctccccgggg agagcggcgg ccgggcttcg
     1981 tggcagcacg tcgcaccgca ccgggcacag atggcactgg ctgttttttc aaattccggg
     2041 ttcacgaaca aacctccccc tttcaggtct ccagaagagc gtggacgatc tccctgtaca
     2101 cgtgcgggta ggacccgtcc tctccaccct cgagcgaagg gttgtcgttg acttcgatca
     2161 cttttggctc ttttccgtcc ttgatatcga caccgtagag cccgtcgccg attgctttcc
     2221 cggccgcaac accgaggtcc cgtatggggg cgggaacggc gtcaggcggg acgctctcga
     2281 cggcgcagta caccacgtgg ccgttgacag agtcctggat cttgaaggtc tgcgagggta
     2341 tgatgtactt gcacgcgtag aggaacctgc cgcggaggac cccaatcctc cagtcgtatg
     2401 tgctctgaac gtattcctgg gccacgaccc agtcggacat cttgaggtag cgccgggcga
     2461 cccggatgaa ggcagccggg tcttcgaccc gctcgacgcg gagggaaaaa gatgtcgagg
     2521 gctctttcag gacgaggggt gtcccgaggt cgtccatgat gtcccggaca cggctgggat
     2581 ggatatctcc ctttgagaga aagagtgtcc ttgggatcgc gacacctgcc ctcgcaaggt
     2641 gcatgtacat gttcaccttg tcggagcaga cctgtatgga ttcggggtcg tcaatcacgg
     2701 gaattcccgc aaacgcagcc atcctcgagg cgacgtacgt gatgttcatc gggtcggtcc
     2761 gtgcccggat gaagagggca tccatctgcg ggatcttccg gatgtcgaca gggaagatga
     2821 actcgacgga gtgccccatc tcctcggcag cgtcccggca ccgtatcagc gatgtcagct
     2881 ggtccgagga ggagagggtc ctgcggtcga caaagatacc gagcctgctc ataggaagac
     2941 ctgcccaaag atgcaagcct tgaggagtcg ccgttcggct ggctggaggc gggagtaccg
     3001 caccgggcag agggacgaga gcacggggcc gccggggccg gagaggcaga ccagctcgac
     3061 gagcgggatg cggaagcact cccagacgct tccggccatc tcctgcatgc cgggaacggg
     3121 ggaaaggacc tttccaaaga cggagactgc gcgggtcacc gccatatccg gggagatcgg
     3181 ctgggaacag caggggtact tcccgccgtt ggtcacgtgc ctcaccttct cgcggtcacg
     3241 cgcatccccg gtgagcacct cgaagtgcga ggtggaggca aagtagttca gcccgtacac
     3301 gattgccggg gcaggggcac acgagtgcat gatggtatac gcggcgacag gtatcccgca
     3361 gtgccctgcc cgctcgaggc agaccgggac gacgaaggcg tcgagcatcg actgcgtatc
     3421 aggcgcaacg gcctctcccg caagctcgcg ggcaaggatg gcatagtacg tctcgctctt
     3481 gtacgagtag ttctcggaaa caaaggtcgt atacccgccg tatcggacgg tgtagacgcg
     3541 gtcgcgggcg aggtggaacc cccggcggtt caccgccgct gccggtactc ctccctgctg
     3601 ttcagccggt gtcgcgatgc cgggtgacac gccgttcatg ggatgcccct ccccctgccc
     3661 tgcagcccgg ctggaaagaa tacgttctct cccggcgatt ggtatgaaaa acaggcagga
     3721 ctcaccctat catgggggtc atcatcgttc tcggtttccg gttctgacat gaaacccacg
     3781 ggccatgcca cgaaggacgg cccattttct ggtatgactc agtggttgca tgccgacggt
     3841 ttaaagtttt gtggtcattc cggggataaa acccgcacat tgcaccagaa agggagtttt
     3901 tctccgcggt tcccacagcg cgctccggga gtgtcggggg ggtttggtct cttctgccgg
     3961 ttatctccat tccccggaga tggcggggga tcaccgtcct ttgcgttacc ggatctcgat
     4021 ccgttccccc gtgaccaggt agtggacctt ctctgctatc ttgcacgagt ggtcagcaca
     4081 ccgttccagg taccgggcga ccatcaggta attcgtgcat cgcgtgatcg tgcgggggtc
     4141 ctccatcatg tacgtgatcc cctcgcgaaa gatggtgtgg cgcagtttat cgaccacgtc
     4201 gtccctctcg tggtggtgtg cgatcaggcc aaggtcaccg gtttcgtatg catgcagggc
     4261 atcgtcgatc atcgagagga cgagctttgc catgtggggc agcgagaggg cgttgacgag
     4321 gtcgtcgggc cgggtctcac cgagagagag gacgacaccg gcggtatcct tgccgtagcg
     4381 cccgatccgc tcggcggatg agatgatctt gagggcacag gcgatctccc gcatgtcgcg
     4441 ggcaacaggc tggtagaggg caatcagcct gtatgcgtct tcttcgagcg tgtcgttttg
     4501 gccggagagc cggaccttcc tctcttttac ctcacgtgcg agtccggtgt cgttttcctg
     4561 cagagcccgc atcgcgtcag aaagcatctg ttcagcaaaa aaacccatcc cgaggactcc
     4621 tgccctcatc cgtgccaact cgtcgtggaa cttgtccttc attgacccac tccccctatc
     4681 cgaaccttcc cgtgatgtag ttctcggtca gctcatcgcg gggactctcg aagatctgtg
     4741 tcgtcccgcc gaactcgatc agtctcccga ggtacatgaa cccggtgtaa tcgctcaccc
     4801 gggctgcctg ctgcatgtta tgcgtcacga tgatcacgca gtactgcttc ttcaactcgt
     4861 cgatgagccc ttccactttt gccgtggcaa tcgggtcgag ggcagaacag ggctcgtcca
     4921 tcaggatgac ctcgggctcg acggcaagtg tccgcgctat gcagagcctc tgctgctggc
     4981 ctcccgacag gctcagtgcc gaacgggaca gccggtcccg gacctcgtcc cagagcgctg
     5041 cacgccgcag gctctcctcc acgatggaat cgagtgtgcg ccggtccctg ataccgtgga
     5101 cccgcggccc gtaggcaacg ttttcgtaga tggacttggg gaaagggttt ggtttctgga
     5161 agaccatgcc gatgcgccgg cgcaggctga cggggtcgga cccgttgtcg tagatgtttt
     5221 cgccgtggta catgactttg ccctcgatcc tgcaccccgg caggatgtcg ttcatccggt
     5281 tgaaacagcg gatcagggtc gatttcccgc agcccgacgg cccgatcagg gccgtgacct
     5341 tccggtccgg gatttccatc gatacgtcca cgagggcacg ggtgtccccg taccacaggt
     5401 tcagcctgtc tgttgcaatg attgtgtcag ggctcatgtc atcaccagtg cgtgttcttc
     5461 tggtagtgcg tgcgaatgcc tatcgcgatc gcgtagaaga ggatcacgag gagcagcagc
     5521 acgacggcag ttgcgtactt gttcgcttcg gcacccggaa tgttcgttgc caggatgtac
     5581 aggtggtagg ggagcgccat gaccggcgag aacggggaat ccgggagaaa ccgctgggag
     5641 aagacgaccg ccgtgaagag gatcggggca gtctcccctg cagcccgccc gatggagagg
     5701 atggcgcccg tgacgatccc gggcacggcc ggcgggatga cgacgcggga taccgtctgc
     5761 cactgcgttg ccccgagggc aaggctcccc tcgcgcaggg aaaccggcac gcccttgagg
     5821 gcctcctccg tcgtccggat gaccgtgggg agtatcatga ggccgagggt gatctgcccc
     5881 gcgatgaggg agaccccgaa tttcaggaag aggacgagga acgcgaatcc gaaaaggccg
     5941 aaaacgatgg atggtgtccc gttcaggagt tccgtccctg tcctgacgat cttcgtgagc
     6001 ctcccctccg ccctgtactc ggagaggtag atcgcggcac cgatgccaag cggaagggca
     6061 aagccgattg cacctgcaac gaggtacagc gtcccgacga ttgccgggaa gatacccccg
     6121 ctgcggccga ggtcacgggg cggttccgtg aggaattcaa aggagagtgc cggcagtccc
     6181 ttgacgagga tgtccgagag gatgacggca aggatgagga ggacggtcgc cgtggcggca
     6241 gaaatgaaaa aaaatgcaat tttctgggtg gtgcggggcg aaagccgccg ccacgagagc
     6301 gcgacgaggg agaacaggaa tacgcagccg gcgtaaccgg cgatcccggc agcgggaagc
     6361 ccgatgagcg agaggactgc caccagcagg accattttcg ctctttcccg catttcggga
     6421 gacaagaggg acgccctgcg gctgcccggc accgtattcc cgcatggtct tcccggtgca
     6481 tactgttccc gcaaccgccc gatgatcgtt gtcgccacga gattgacggc gagcgtgatg
     6541 accaggagga cgacggcgac accgaagagt gcatggtaat gcatgctccc cgtggcaact
     6601 tcccccatct ctatcccgag cgtccccgtc agtgtccgga cgggggagag gacgttccag
     6661 aggggtgaag gcacgatggc cgcgttcccg gtcaccatca ggacagccat ggtctcgccg
     6721 attgccctgc ccatcccgag gatgacggca gccgagatgc cggggagtgc cccgggcacg
     6781 atgacccggg atatggtctg ccagtgcgtt gccccgaggg cgaggctccc ctccgaaaac
     6841 tcccggggca cgcacgacag tgcatcctcc gagacgctga taatcgtcgg cagggccatg
     6901 atgccgagga tgatcgagcc tgcaagccac gactcgcccg aggggacgcc gaacgttgcg
     6961 cgtatccagt cggtgaggac gatcagcccg aaaaacccgt agacgacgga gggtatccct
     7021 gcgaggagct cgatggcagg tttcacgacg gcacggactg cagggggcgc aagccgggcg
     7081 acgcagatgg cacacgcgat accgaggggc accgcaattg ccattgcgcc gagggtcacg
     7141 cagagcgtgc ctgcaacgag cgggacgata ccgaattttt caacgggata ccctgtcggg
     7201 ttccattccg tgccgaggag gaagctggtt atccccgttt cggagagaac gggatagccg
     7261 tcccggatca ggaacgcgag gatgaagaag atcgtgacta tggcaatgcc tgcacacgat
     7321 aggaggatga gcctgatgag ggtctcccct gtcctggccg ggatcagtcg tccttgtttt
     7381 gtttgccggg ggagggggag tgtcatgggg ctttccggga aaaagggggt ttttcgtcag
     7441 gatcaggcct gacccagcgg gacgaaacct tctttctcca ggatcttctg gccttctggt
     7501 ccgagcagga atgtgatgta gtcctttgca aggcccgcgg gctctccctt cgtgaccagg
     7561 atgagcggcc gggagatcgg gtatttcctg tcgagcaccg tccggacgga tggttcgatc
     7621 ggggttccat tcacgaggat cgggactgcc ctgaccgttc cgtcgatgta tcccagcccc
     7681 acgtacccga tggcgcccgg tgtctgggca accgtctgtt tcactgcacc gttcgagttc
     7741 ttctcgagct gtcctgccac gaagtcttcc ttgttcatca ccttctcgtg gaagaattcg
     7801 cgtgtgccgg acgcactgtc cctgcctgcc acgacgatgg ccatgtcagg accgccgagg
     7861 tccttccagt tcgtgtattt cccctggtag atccccttga cctgctccag ggtgaggggc
     7921 ccgaccgtgt ttgacgggtg cacgatcagc gctatcccgt cgttgccgat gaccgtgctg
     7981 acgagaccgg ggtaacgggt cttttcctcg gccttgaggt cacgcgagga catcccgatc
     8041 gaggcagtcc cttcccctgc agcctggatg ccaacgctcg aacccccgcc gatcaccatg
     8101 atctcggcgt tcgcatgggt gttcatgtag gcgtctgcag cagcctgggc gacggggagg
     8161 accgtcgtcg atcccgagag cgtaatggac tcgcgggtct tgcccgggga agtcgtggtc
     8221 ggaggctgtg agccggcctg ctgcgtgcaa ccgcaggcaa ggagcgccat cacgaggata
     8281 agcgccaaaa gtgtggcaat ggatgccggg ttccgcatac cgttcattct ggttcaaaaa
     8341 aggaagggtg accatcagat atggtatttc ccgaaggaaa atatagtagt ctccgtataa
     8401 tatgtatcaa tatagagaaa caagggagcc gcgggaagca tccggaccgg gtcatccggg
     8461 agatgtacct gcagcagtga tcaccatccc atgcagggtg accgctgggg acgtgtcctg
     8521 ccaccggggc caagctataa gaacggggca cgggatacag acagcaggga ggcaccgatg
     8581 ggaggagaca acctcgtcga ggtaacggac agcacatttg aaaagacagt cgaaaagagc
     8641 agtcttccgg ttcttgtcat gttctacagc ccgacatgcg tccattgcag ggcaatggaa
     8701 ccccacgtcc gggaatacgc ggaggtcttt gcagggcgtg tcctctttgc ccgcctcgat
     8761 gtcattgccg gccagtggac agccgagcgg tacggcgtcc ggagcactcc gacgttcaag
     8821 ttcttctgca gcgggaggcc gatatcagaa ctcgtgggtg ctgtgtatcc cgcactcctc
     8881 aaaaggatgg tcgaggacgg cctgcagaac gggaaggagt gcgtgacgca ctcgacggca
     8941 gtcaactacg acatcacagg gtacgcctga ttcccggcgg gcgcccctct cccctgcgcg
     9001 tggtgcgggg ggactcgcgg ccccggttgg taaaggaagc cctcctgtcc catccgttca
     9061 ccggcatctc aacaggtata aatatagccg atcccatatt gttgttatta aaatgacaac
     9121 aataaaccgg aaggcactac ctctcttctg catcatcctc actgcaggac tcatccttgg
     9181 tcctgtccag gcagcagaaa aataccttgg cgagagtccg gaccttgcgg tctccatcgc
     9241 gggtgcaaac gagtactacc cgggaaaaga ggtgacgatt tctgttcttg tcgagaaccg
     9301 tgccaccccg gggactaaga tcatcgcgcc gggacaggac cagtggccgg accgtcccac
     9361 caccgcgaag ctcgtcaggg ttgcactcct tccgggcgat gcccctgtca tcatcaggac
     9421 cgatccgcag atgatcgggg acctgcctct gggttcgagc aggagcgtcc cgttccaggt
     9481 caagataccc gaaggggcaa ggggtgggac atatacgctt cctgtcgatc tccagtatac
     9541 ctccatctcc tttgccgagc aggtcggcac tgacacccag atcctccatt acaaggatgc
     9601 caatatcacc cggtctgtcg aggtgaaggt caggccccgg ctggtattta cggtgacgaa
     9661 cgtgacgggg gcagaaatct cttccgggca ggaaggggaa cttgcggtga cgatcaggaa
     9721 taacggcacg ttcaagggca gggatgcgac ggtccggata atccgccatg acgggagccc
     9781 cgtcataccc gtggagggaa gcgcttacat cggggatttt gcgcccgggg actctttttc
     9841 aacgacgttc cgcgtccgtg tccctgatga tgcgcagggg accacgtacc ccctcgacct
     9901 cgtcatccgg taccgggatg acgaggatga cctcgttgac tctgacaggg agacgatcgg
     9961 agtcccggtt catggcaggg cagaattctc gatcgagcct gcagaggtga ccatcccgcg
    10021 gggactgtca cgtgacattg cgctcaccat caggaacacg gggcccgtga ccctccggag
    10081 tgcacaggcc agggtgaagg tcattgagcc cttctcctca tcgaaatata cagccgccct
    10141 cggggacctt gctcccggtg aggaggccac cgtcaccgtc tcccttgccg tggacaagtc
    10201 agcgacaagg aaggtctacg ggctggacac ggagatccag tacagggacg cactcgataa
    10261 catcgttgtc acgtccccgt ccacgctgcg gattgccgtg gtggacagga acatcatcga
    10321 atcggtcacg acgaaccctg tctccatcag catcatcgtt gccgtcatcc ttggtgcagt
    10381 ctacttttac tacaggcgga aaaagggtga ataagaaaga ttcttcactt ttttgaccgg
    10441 gtcgcaggaa ttgaacgggg ggactccccg cccccgcacc ccccaaaata cgtcccgcca
    10501 gcggtgtcag gactcaattt cggtaaatag cgacattttt tcttcggact acctgattcg
    10561 aaactgcacg aggttaataa agagtactcg tgccctgcat ccgctcgaaa tgacggagaa
    10621 aaaaaaaggt cttgtgccac tgtcctcaac cggtgatggc ggttgaaagc cctggccgtc
    10681 tgtggaaagg cagaaaaaaa gggaaaaagc ggttaccagc tctctgcaaa tgcagtgttc
    10741 acgtagatgt cttcgagccg ggccttgtgc ccccgctcca tgtttgcgag ctcaaggaac
    10801 atcttctttt gttgcgcgtc ctcgctgttg tttgcaaggg cggtgtacat ctgcatggcc
    10861 tcgagttcct tcttgatcgc cacgacgagg ccatcgaccg gcttcatgtc aggcttgaga
    10921 tccggtgtct tgatgttgtc cccgaccttg tagtccttgg ttgccgagaa cttgagtgcc
    10981 ttgacgtcct tggaaaggag tccctgcagg aattcgcggt gctttgtctc ctcgcccgca
    11041 agctcgttga agagcttctt gaggttggca tcctttacct tgtctgaaac cgtcttataa
    11101 aaggtatatg cctcgacttc acggttgata gcattagaaa tgatcttctt gtagtcttca
    11161 ggagtcatcg atattcctcc gtgtcgttac tatgatcctc attatttaaa tagaaattgt
    11221 tcccgcctct cagtgcgtaa cgccattata tcggggggaa ccgtgttgcc cgatgggtgg
    11281 gatgatgcac gggaagtatg ccgggtacat gccctgccct ttggcgactg accaggaaat
    11341 ctgccggagt cctgtcgccc gttt
//
LOCUS       DAOOJU010000040        11132 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5328_length_11132_cov_15.235082, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000040 DAOOJU010000000
VERSION     DAOOJU010000040.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 11132)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11132)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11132
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5328_length_11132_cov_15.235082"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(186..407)
                     /locus_tag="PK679_08300"
     CDS             complement(186..407)
                     /locus_tag="PK679_08300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC55990.1"
                     /translation="MENTNAKDFSELTCTNLMIKLKILLNKLSPGDTVAFYATREQVD
                     NTCSPFSGQGYQVTWTEVAANRYLVRIGK"
     gene            complement(422..1552)
                     /locus_tag="PK679_08305"
     CDS             complement(422..1552)
                     /locus_tag="PK679_08305"
                     /inference="COORDINATES: protein motif:HMM:NF014672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HPC55991.1"
                     /translation="MRWLAGVIGTGGGQEHSGDTGNVKIFLTGDALFSLVDARTRPAW
                     ATLSRLPSVLVIADGDELRLQGLADPVASGIPGLRITGSANRESFWGELVSSLEKDWP
                     GTRSAAFLLCTSPYMSRVPVYMLRFLTCVLGAGLHPELYCYLDGVHTLHDGQRPSEFE
                     NIGKGVSALSGNTVRACRDPWFAACSRCATARGYYQMNPGTGFCEPASCIQDIAIKPL
                     KEILARFSGFHPIASHMGGWTVPAGDGKEGVPALTVFITHPPYCSEWTFGGLSLAIAA
                     AMDGISTNVVFIEDGVYALQGNHDVPDNDRIFNVQEMIAVTTDIGRLSYYVHAPSVAD
                     RGVSTTGNLSLVREASDRDLSRILFPAKKDPAFTPAMRMLFF"
     gene            complement(1606..2130)
                     /locus_tag="PK679_08310"
     CDS             complement(1606..2130)
                     /locus_tag="PK679_08310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE thiosulfate transporter family
                     protein"
                     /protein_id="HPC55992.1"
                     /translation="MATGVLPMEIAVYAVPAVTLLLGILIGYLAQRSGFCSIGGFRDY
                     FLFRHTRILSGYLALIVFSFLGYLLFWILTPAAMEHFFWALTSGPFIPVPGAPAGLGP
                     AAYILLAVIPGFLVGFICVLLGGCPIRQAVMTSEGNIRAAFFLLGMAVASPVFAAFVS
                     GWIVLLMKSLGLGA"
     gene            complement(2130..2663)
                     /locus_tag="PK679_08315"
     CDS             complement(2130..2663)
                     /locus_tag="PK679_08315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015284691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE thiosulfate transporter family
                     protein"
                     /protein_id="HPC55993.1"
                     /translation="MVPCSIHDTVRRHAFLLVRHPAFLGAVIGILAALSQSLLISAGG
                     PEAYGFCVACHTRDLVNGVTNILAGSSLALAPISKNAVLPVMSVVGVLIGAYVSARVN
                     REHAVKKGSFRDYLLYFLGGFLVLILAMVFGGCPYRAALRTGYGDIIALLFIVAMALG
                     VVAGTVFMLKRAEREEA"
     gene            2797..>3439
                     /locus_tag="PK679_08320"
     CDS             2797..>3439
                     /locus_tag="PK679_08320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011447894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HPC55994.1"
                     /translation="MTAINDLFTAGQFFLVITLELVLLFVAISFLVGLIQEYVPEEKI
                     RRALSSGNRVTGTALGAFFGALTPFCSCSTIPVLVGLINSRVPFGACMAFLLASPLLN
                     PVIVFMVLAFFGPVPTVIYCAITFCIAVLSGLVLEERGFIRFVKPVGPGKNAISSGAG
                     SGCCAGNPVRPAKASTGCCPGDTGAITPSVGCCSDEPVRPAKASTGCCPGDTGM"
     assembly_gap    3440..3539
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            3591..4127
                     /locus_tag="PK679_08325"
     CDS             3591..4127
                     /locus_tag="PK679_08325"
                     /inference="COORDINATES: protein motif:HMM:NF015715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HPC55995.1"
                     /translation="MTTQATGCCAGGSTPIPAAPPASANPGVNGSPGSHHGRRMKSAL
                     GFSLRLFRQVLPYLILGAAIGAFIYGFVPEDLIVSLAGPENPLAIPIAAIIGIPMYIR
                     AETIIPISAVLLTKGMGLGAVMALIIGGAGASIPEVTLLASIFERRLVAAFVGVVLGV
                     AISAGIVLQVLQTAGLLG"
     gene            4171..4569
                     /locus_tag="PK679_08330"
     CDS             4171..4569
                     /locus_tag="PK679_08330"
                     /inference="COORDINATES: protein motif:HMM:NF033788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HPC55996.1"
                     /translation="MTGRTGRHRASSLSRYITIFKALSDETRLRIYLLLGGGELCVCH
                     IQAILGTTQTKVSRHLGILRNAGLVTARREGLWIYYRRSEPGPPGVRSFTRDLARLLD
                     TDPGPGGREGRDGHCECEEGKVSHGKDTRH"
     gene            4547..4981
                     /locus_tag="PK679_08335"
     CDS             4547..4981
                     /locus_tag="PK679_08335"
                     /inference="COORDINATES: protein motif:HMM:NF022321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2703 domain-containing protein"
                     /protein_id="HPC55997.1"
                     /translation="MAKTLVIEWKHIGNDVTGTCERCSLTGGAIRDVLKDLGPYFRQK
                     GIIPEFRETVLPDAEIGVSNQVLLDGRPLEDFLAGAEVVSTPCCSCACITGQDEAYCR
                     AIEYRGHRYEAITPDLLKQVIIGVVESKKGTCDCGCACNGRS"
     gene            5040..5471
                     /locus_tag="PK679_08340"
     CDS             5040..5471
                     /locus_tag="PK679_08340"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004078601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase ArsC"
                     /protein_id="HPC55998.1"
                     /translation="MSASEKKRSVLFICTHNSARSQMAEGYLRARYGDRFDAFSAGTT
                     ATRVHPLAIAVMEEIGIDISGQRSKPVTEFYGREMDLVVTVCDSARSACPFFPWAKET
                     LHVPFPDSAGREGESPVDVFRKVRDGITGWIDGHFGRGETG"
     gene            5468..5875
                     /locus_tag="PK679_08345"
     CDS             5468..5875
                     /locus_tag="PK679_08345"
                     /inference="COORDINATES: protein motif:HMM:NF020434.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc-binding protein"
                     /protein_id="HPC55999.1"
                     /translation="MKDEDRPVLLLTCSGISHTGQLTTLAGRFIRSMYPALLSRHLVL
                     TGLTRSLEEELDGDERLVVVDGCDQCCARKRVLLAGKVMDGHLVATAEGIAKRGMEEP
                     RFDEIQKLSHVIMRIVKNDGHISHRVPPGQDHE"
     gene            5868..6332
                     /locus_tag="PK679_08350"
     CDS             5868..6332
                     /locus_tag="PK679_08350"
                     /inference="COORDINATES: protein motif:HMM:NF040494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrophenyl compound nitroreductase subunit ArsF
                     family protein"
                     /protein_id="HPC56000.1"
                     /translation="MNKRSIVILPVLLFVFAYLLAAGCLTQGNTGESAGNRSLSSVDK
                     VEVYHFHATRQCYSCIVLGEYAEETVKTYFGPELASGKLVFGHINVDLPENRAIVEKY
                     GPTGSSLWIGVTNRGEFSKEENIRVWYKIGNKEEYMDYLKGVIEKRLAGDLS"
     gene            6329..7060
                     /locus_tag="PK679_08355"
     CDS             6329..7060
                     /locus_tag="PK679_08355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014865918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic aminobenezylarsenical efflux permease
                     ArsG family transporter"
                     /protein_id="HPC56001.1"
                     /translation="MTGVMGAMEALGTSGIPLVAAFFIGLLMTFSPCPLATNITAIAF
                     ISKKIGDSRHTILVGTLYSLGRMAAYIALTALIVHAGLNIQAISFFLQEYGERLIGPF
                     LVVMGVLMLEIVQIPFSGGQGRLQAIELYLGEKGYLGAFFLGVIFALALCPFAAVLFF
                     GMLVPIALKTGDALFVPAVFAVATALPVIVISLILVRSVNRVSNVMQKVQDMEKWVKW
                     AVAAVFICTGLYYIAIVYGPAIGLG"
     gene            7267..8679
                     /locus_tag="PK679_08360"
     CDS             7267..8679
                     /locus_tag="PK679_08360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-ATPase domain-containing protein"
                     /protein_id="HPC56002.1"
                     /translation="MRDAGTDACLEGILSLSGDSRWEIDRAHAARNVTAYVVRSFDGS
                     ALVFSLPLLVLRPLCAEIPLDPRGSAGAVACIIERIKEKAASDEALGPLVGRGCRFPH
                     QFAALTEPYTVVSSPAALASHLWHAGGRNVADGRGVHLLVGGAVPCPAAFPHREVRGF
                     IGTVARFCEAVAKVTFSVPARELEAAWMNALDQQILREMLPGKGLVSFVGDGAHLARS
                     YTRYRCYFRTAGPKTGMSIPFTCPPDLSPIELELPASKRIVTGLGIRKKEVFAVAGSN
                     AEGKTTFLEGIIAGMDDHAPGDGREMVVTVQGLCTAEATNAIMTGADVSMFFSSLPPG
                     ISGTVHAASGMGSGSMSMAYQVQRAVDRECPLLIIDEDRAAPNLLVGSALQKDDVTPL
                     SAILCHDRGRMKETALVFAACAMDTLVAQADRIMVLDRHVAHAIDREEFRKRVALSLG
                     KMARDLMAGEKRGNAGERRD"
     gene            9247..9927
                     /locus_tag="PK679_08365"
     CDS             9247..9927
                     /locus_tag="PK679_08365"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: protein motif:HMM:TIGR00290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HPC56003.1"
                     /translation="MPEKQEGKTVVVSWTGGKDGCFACYRAMEKGYKIARLLHFTNRK
                     KRGSHELNPGIIRAQSVATGIPLIQRDFFSYEEEFRKVILELREQGERIDGAVFGHIQ
                     THGSLVERICRDLDLEIVMPLWKKDSERLLADMIDAGFEIVIASTRADVLGEKWLGRI
                     IDGAFPGEIRTLGVPVDPCGENGEFHTLVTDGPIFRKKIIITRSEPAFFDGYWYMDIR
                     DFSLQQKG"
     gene            10087..11094
                     /locus_tag="PK679_08370"
     CDS             10087..11094
                     /locus_tag="PK679_08370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoU domain-containing protein"
                     /protein_id="HPC56004.1"
                     /translation="MEIRKVQVTGGSSYVITLPKEWVQAQKIAKNEPLGMVVQSDGSL
                     LVTKEINEKTISRVRKIDVTAIDDPTYLFRLLIGIYIAGFTTIELFSRTRLPPSIGLI
                     VRDFTQVAIGPEIVEETDNRIVLKDLLNPTEMPFDNTLKRMYVIVKNMYLDAMNAMET
                     RNGKLIEEIISRDSDVDRLHWLIARQSSIVLKNPEVARRMGVSPHMVMNAMIISRIIE
                     RIGDHAVRWAENARQIIDHDLDARILKHMKDASTLALSIFDRSITAYYKADIRESHRN
                     IEQVSTLEELCEELNQLVMEEEPDVAVALRYISESIRRSGEYAGDISETVMNYLVEEK
                     I"
BASE COUNT         2378 a         3067 c         3377 g         2210 t
ORIGIN      
        1 taagagagat gaccgggtcc atgcagggag caggtgcggg ggagaagaat atggggtgcg
       61 ttttctcgca ggccagggag agacatcggg gtcgcaacgg tccgggatcc ggcattcggc
      121 aacgtcccct gccagaccat ccattcggga ggtctttgtg gaccccgtgc ccggaaaaag
      181 ccccctcact tcccgatgcg gaccaggtac cggttcgcgg cgacttctgt ccatgtcacc
      241 tggtatccct ggccggaaaa aggggaacac gtgttgtcca cctgctccct cgttgcgtaa
      301 aaagccacgg tatcgccggg agaaagcttg ttcagcagga ttttcagctt tatcatcagg
      361 ttggtgcagg tcagttcgga aaagtccttt gcgtttgtat tctccatggt atcacatcct
      421 ttcagaagaa cagcatgcgc atggcagggg taaaagcggg gtcttttttt gccgggaaca
      481 ggattcggga caggtctcgg tccgaggcct ccctgaccag cgacaggttc cccgtggtac
      541 tgacgcccct gtccgcgacg gaaggggcat ggacgtaata agagagtctc ccgatatcgg
      601 tcgtgacggc gatcatctcc tgcacgttga agatccggtc attatcgggc acatcgtggt
      661 tcccctggag ggcatacacg ccatcctcga tgaagacgac gttcgtcgaa attccgtcca
      721 tggccgcggc aatggccagg gagagtcccc cgaacgtcca ctcggaacaa tagggagggt
      781 gcgtgataaa cacggtcagt gcggggactc cctccttccc gtctccggcc gggacagtcc
      841 agccccccat gtgcgaggcg atggggtgga acccggaaaa ccgggcaagg atctctttca
      901 gtggcttgat cgcgatgtcc tggatacagg aagcaggttc acagaaaccc gtgccggggt
      961 tcatctggta atatcccctc gctgttgcac accgcgaaca ggcagcaaac cacgggtcgc
     1021 ggcatgcccg tacggtgttc ccggataggg cagatacgcc tttgccgatg ttctcgaact
     1081 ccgaggggcg ctgaccatcg tggagagtgt ggaccccgtc gaggtagcaa tagagctccg
     1141 ggtgcagccc agccccgagt acgcaggtga ggaaccggag catgtagacc gggacccggc
     1201 tcatgtaggg agaagtgcag aggaggaatg cagcgctcct cgtcccgggc cagtcctttt
     1261 cgagggaaga gacgagttct ccccagaaag actcccggtt ggccgacccc gtgatacgaa
     1321 gacccgggat cccggatgca acagggtcgg cgagtccctg aaggcggagc tcgtcgccgt
     1381 ctgcaatgac caggacggac ggcaaccggg agagggtggc ccaggcaggg cgggtccgtg
     1441 catccacgag gctgaagagg gcatctcctg taagaaatat ctttacattc cccgtgtccc
     1501 cggagtgctc ctgccctcct cccgtgccga tcaccccggc gagccacctc atgcgttccc
     1561 cgctgatggg atcgcagaag aggaacgttg aggagaacac aatgatcagg cccccagtcc
     1621 aagggacttc atcaggagga caatccaccc cgatacgaac gccgcgaaga ccggggaggc
     1681 gacagccatc ccgagcagga agaacgcagc cctgatgttc ccctcggatg tcattacggc
     1741 ctgccggatg gggcatccgc cgaggaggac gcagataaat ccgacgagga aaccggggat
     1801 cacggcaagg aggatgtagg ctgccgggcc aaggcctgca ggggctcccg gaaccgggat
     1861 aaaaggcccg ctcgtgagtg cccagaagaa gtgttccatt gctgcaggtg tcagtatcca
     1921 gaagaggagg tacccgagga acgaaaagac gatcagggcc aggtaccctg agaggatccg
     1981 cgtgtggcgg aagaggaaat agtcgcggaa ccctccaatc gagcagaaac cggaacgctg
     2041 ggcaaggtag ccgatcagga taccgaggag gagagtcacg gcagggaccg cgtagaccgc
     2101 aatctccatg ggcagaacac cggtcgccat caggcctcct ccctttcggc ccgcttcagc
     2161 atgaagaccg tgcccgcaac gactccaagt gccatcgcca cgatgaagag cagggcaatg
     2221 atatccccgt agcccgtccg gagagccgcc ctgtacgggc accccccgaa gaccatcgcg
     2281 aggatgagca cgaggaaacc cccgaggaaa tagagcaggt agtcccggaa cgatcccttt
     2341 ttgacggcgt gctccctgtt cacgcgtgcg gatacgtatg cgccgatgag cacaccgaca
     2401 acactcatca cgggtaaaac tgcattcttc gagatgggtg caagggcaag ggatgacccg
     2461 gcaagaatat tggtaacccc gttcacgaga tcccgcgtgt ggcatgcgac gcagaacccg
     2521 tacgcctcgg ggcccccggc actgatgaga agcgactggg acagtgcagc gagaatcccg
     2581 atcaccgcac cgagaaacgc gggatgccgg acgaggagga atgcatggcg gcggactgtg
     2641 tcatgaatac tgcagggtac catgggtcat tacatttcga catttttcac tataatattt
     2701 tggaaccatt tatgcactta tgtgacacaa aatgcaaaga tcggcaggga gattcaaaat
     2761 cattatattt ggataaccga atataggtat atacagatga cagcaataaa cgacctcttc
     2821 acggccgggc agtttttcct ggtcatcacg ctcgaacttg tcctcctctt cgtggccatc
     2881 agcttcctgg tagggctcat ccaggaatac gtccccgaag agaagatccg ccgggctctc
     2941 tcgtccggga accgggtcac ggggacggct ctcggtgcat tcttcggtgc cctgacaccg
     3001 ttttgctcct gctcgacgat ccccgtgctc gtcgggctga tcaactcccg ggttccgttt
     3061 ggcgcctgca tggcattcct ccttgcatca ccgctcttaa acccggtcat tgtcttcatg
     3121 gtgctggcat tcttcggacc ggtaccgacc gttatatact gtgcaatcac cttctgcatc
     3181 gcagtgttgt cggggctcgt gctcgaagaa agggggttca tccggttcgt caaacctgtc
     3241 ggaccgggaa agaacgctat ctcctctggt gcaggatcgg ggtgctgtgc aggtaacccg
     3301 gttcgtccgg caaaggcaag tacgggctgt tgtccgggag atacaggcgc gatcacccca
     3361 tcagtggggt gctgttcaga tgaaccggtt cgtccggcaa aggcaagtac gggctgttgt
     3421 ccgggagata cgggcatgan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc
     3541 cggttcgtcc ggcaaaggca agtacgggct gttgtccggg agatacgggc atgaccacac
     3601 aggcaacagg gtgctgtgca ggcggttcaa cgcccatccc cgcggctccc cccgccagtg
     3661 caaaccctgg cgtgaacggt tcacccggat cccaccatgg ccgccggatg aagtctgccc
     3721 tgggtttttc cctccgcctg ttccgccagg tacttcccta cctcatcctc ggggctgcaa
     3781 tcggggcgtt catctacggg ttcgtgcccg aggacctgat cgtctccctt gcgggtccgg
     3841 aaaaccccct cgccatcccc atcgcagcca tcatcggcat cccgatgtac atcagggcgg
     3901 agacgatcat tcccatcagt gcggtcctgc ttacgaaggg gatgggcctt ggcgctgtca
     3961 tggcactcat cattggcgga gcaggggcaa gcattcccga ggtgaccctc cttgcatcca
     4021 tcttcgagcg gaggctcgtt gcagcgttcg ttggagtcgt cctcggggtc gccatcagtg
     4081 cggggatcgt cctgcaggtc ctgcagacgg cagggcttct cgggtgaaga tcactggatt
     4141 tatccgggtt taccaacgag gtattagtac atgacgggga ggacaggacg gcaccgggca
     4201 tcgtccttgt cccggtatat caccatcttc aaggcgctct ccgacgagac gaggctccgg
     4261 atctacctcc tcctcggtgg cggggaactt tgcgtctgcc atatacaggc catcctcggg
     4321 accacccaga ccaaggtctc ccgccacctg ggaatcctgc ggaatgccgg cctggtcaca
     4381 gcccggcggg aggggctctg gatatactac aggaggtcgg agccgggacc ccccggagtg
     4441 agatccttta cgagggacct tgccaggctc cttgatacgg acccgggccc tggcggacgg
     4501 gagggcaggg acggtcattg cgaatgcgaa gagggaaagg tttcccatgg caaagacact
     4561 cgtcattgaa tggaagcaca tcgggaacga tgtgaccgga acgtgcgagc gctgcagcct
     4621 gaccggcgga gcgatacgcg atgttttaaa ggacctcgga ccctatttca ggcaaaaggg
     4681 catcataccc gagttccgtg agacagtcct ccccgatgct gagatcgggg tatcgaacca
     4741 ggtcctcctc gacggcagac ccctcgagga cttccttgcc ggtgcggaag tggtctcgac
     4801 cccctgctgt tcctgtgcct gcatcacggg acaggacgag gcttattgcc gtgcaatcga
     4861 gtatcgggga catcgctacg aggcgattac ccccgacctc ctgaaacagg tgatcatcgg
     4921 tgtggtggag agcaaaaagg gaacgtgtga ctgcggttgt gcctgcaacg gccggtcctg
     4981 aaaggacgct ccggcaggtt gcgggggaaa aagccgggag aggggggtga aaggacacca
     5041 tgagtgccag cgaaaaaaag aggagtgttc tcttcatctg cacccacaac tctgcacgct
     5101 cccagatggc tgaaggttac ctgcgggccc ggtacggcga ccgtttcgat gccttctcgg
     5161 ccgggacaac ggcaacccgg gtccatcccc tcgccattgc ggtcatggaa gagatcggca
     5221 ttgatatatc cggacagcgc tccaaacctg tcacggaatt ttacggaaga gagatggacc
     5281 tcgtggtgac ggtatgcgat tctgcgcgga gtgcctgccc cttctttccc tgggcaaaag
     5341 agaccctcca cgtcccgttt cccgactcgg ccgggaggga aggggaaagt ccggtcgacg
     5401 ttttccggaa ggtccgggac gggatcacgg gatggatcga cgggcatttc gggaggggtg
     5461 agacgggatg aaagatgagg accgtcccgt tctcctcctg acatgctcag ggatctccca
     5521 cacggggcag cttacgaccc tcgcagggcg ctttatccgg agcatgtacc cggcccttct
     5581 ctcccgccac cttgtcctca ccgggctcac gcggtccctc gaggaggaac tggacggtga
     5641 cgagcgcctg gtcgtggttg acgggtgcga ccagtgctgt gccaggaaga gagtccttct
     5701 ggcaggaaag gtcatggacg ggcacctcgt cgcaactgca gaagggatcg ccaagcgggg
     5761 gatggaagag ccgcggtttg acgagatcca gaagctttcc cacgtgatta tgagaattgt
     5821 gaaaaacgac gggcacatat cccaccgggt gcccccggga caggaccatg aataagagaa
     5881 gcattgttat tctaccggtt ctcctcttcg tttttgcata cctgctcgcg gcagggtgcc
     5941 tgacgcaggg gaacacgggg gagagtgccg ggaacaggtc tctctcttcc gtcgacaagg
     6001 tcgaggtcta ccatttccat gcgacccgcc agtgttattc ctgcatcgtt cttggagaat
     6061 acgcagagga aacggtaaag acgtattttg gacctgagct tgcatcaggg aaactggtct
     6121 ttggccatat aaatgtcgat ctcccggaaa acagggcaat cgtggagaag tacgggccta
     6181 ccggatcctc actctggatc ggggtcacca acaggggtga attttcaaaa gaggagaata
     6241 tccgggtatg gtacaagatc gggaacaagg aagaatacat ggactacctg aagggagtta
     6301 ttgaaaagag gctggcaggg gatctctcgt gacaggcgtg atgggtgcca tggaggccct
     6361 tgggaccagc ggcatccccc tcgtcgcggc gttcttcatc ggtctcctga tgacgttttc
     6421 tccctgcccg cttgccacga acatcactgc cattgccttc atctcgaaga agatcggcga
     6481 cagcaggcac acgatcctcg tcgggacact ctacagcctg gggaggatgg cagcctacat
     6541 cgctctcacg gccctgatcg tccatgcggg cctgaacatc caggcgatct cgttcttcct
     6601 ccaggaatac ggggagagac tgatcgggcc gttcctggtc gtcatgggag tcctgatgct
     6661 tgaaatcgtc cagatcccct tctccggtgg acaaggcagg ctccaggcga tcgagctcta
     6721 tctcggtgaa aagggatacc tgggagcgtt cttcctcggt gtcatatttg cgcttgccct
     6781 ttgtccgttt gccgcagtcc tcttcttcgg aatgctggtc ccgattgcgt tgaagaccgg
     6841 ggacgcgctt ttcgttcctg cggtctttgc agttgcgacg gcactgccgg tcatcgtcat
     6901 ctccctgatc ctcgtcagga gtgtcaaccg tgtctcgaac gtgatgcaaa aggtgcagga
     6961 catggagaaa tgggtaaagt gggctgttgc cgctgtcttt atctgcactg gattgtatta
     7021 catcgcgatc gtgtacgggc cggcgatcgg actggggtga attggttccc gattctccat
     7081 gcaggtttgt gtgagagtgg ctttcggttt gttatcagga atcaggcacg atgataccct
     7141 gtgatttttc cgtcacctgt tttcggcagg gttgagtgtg ccctgcccgg gactcgtcat
     7201 ccaaacctct ccctatgaca cctccaccat tctcctttta ccccttctgc accatacccg
     7261 catagtatga gggatgccgg aaccgacgcg tgcctggagg gaattctctc tctttccggg
     7321 gatagccggt gggagattga cagggcccac gcggcacgaa acgtcacggc ttacgtggtc
     7381 cgttcgttcg atgggagtgc actcgtcttt tcgctgcccc tgcttgtact ccgccccctc
     7441 tgtgcagaga tccccctcga tccacgggga tcggcgggtg ccgtcgcgtg catcatcgag
     7501 cgtatcaagg agaaagcagc ctccgacgag gcactgggcc ccctcgttgg ccggggctgc
     7561 aggttccccc accagtttgc ggcgttgacc gagccctaca cggtggtatc ttcccctgca
     7621 gcgctcgcat cgcacctctg gcacgcgggc ggccggaacg ttgccgatgg caggggtgtc
     7681 cacctcctcg tcggcggggc ggtcccgtgc cccgccgcgt ttccgcaccg cgaggtccgg
     7741 gggttcatcg ggaccgtcgc acgcttctgc gaagcggttg cgaaagtgac gttctcggtc
     7801 ccggcccggg aactggaagc ggcctggatg aatgcccttg accagcagat tctccgggaa
     7861 atgctccccg ggaaggggct tgtctcgttc gtcggggacg gagcacatct tgcccgatcg
     7921 tatacgcgtt acaggtgcta tttccggact gccgggccga agacggggat gagcatcccg
     7981 ttcacctgcc ctcccgatct ttcccccatc gaactggaac ttcccgcgag caaacggata
     8041 gtcacaggcc ttgggatcag gaaaaaggag gtgtttgcgg ttgccgggtc gaacgcggaa
     8101 ggaaagacaa cgttcctcga agggatcatt gccgggatgg acgaccatgc ccccggcgac
     8161 ggcagggaga tggtggtcac cgtgcagggc ctctgcacag cggaggccac gaacgccatc
     8221 atgaccggtg cagacgtgag catgttcttt tcgtccctcc cgcccgggat cagcgggacg
     8281 gtccatgcag cgtccggaat ggggagcggc tcgatgagca tggcatacca ggtgcagagg
     8341 gccgtcgacc gggaatgccc gctgctcatc atcgacgagg accgggctgc tcccaatctc
     8401 ctcgtcggaa gcgccctcca gaaggatgac gttacacccc tctccgcgat cctctgccat
     8461 gaccggggga ggatgaagga gactgccctt gtctttgctg cgtgtgccat ggatacgctg
     8521 gtcgcacagg cagaccggat catggttctc gacaggcacg tcgcccatgc aatcgaccgg
     8581 gaagagttcc ggaaaagggt ggccctgtca ctcgggaaga tggcccgcga cctgatggcg
     8641 ggagaaaaga ggggcaacgc cggggaaagg agggactgac gttgcacggt gcagcaacca
     8701 aggagaagga aggccttgtt cccctctctg ccgtgagtta tatcgaacca cccggggaag
     8761 ccggcaacag ggatccggag aaggtttcag gaagaaaaaa aacccagcct gtgtcctttt
     8821 catacacatt gcccgagccg tttttgagta accccatatc gcaatcacgg gtcaccgggt
     8881 agtactggga gggaaaggca tgagtgcgtc tttgggaaag aggccgggtc gcggtccccc
     8941 ataatatccc ctcgggggaa gagagatatt attgtgtctc gggggaacgt gtcttcagaa
     9001 gagtgttttt ttcgtggaca ccgatccccc ggggttgtgt gcctgcggaa cacggatttg
     9061 acaggtccgc aaccggtcat tctgcatgtg catccggatg atcagtattt atttacaatc
     9121 cattccggga acttcaggag aaaaggatta tagcgggccg gattgcatcc ggtatagaac
     9181 ggcagacccg gcgggtacca gacacgggct ttcttctggc atccgggtct cgatggggat
     9241 gttccgatgc cggaaaaaca ggaaggaaaa acagttgtcg tctcgtggac gggaggaaag
     9301 gacggttgct ttgcctgtta cagggcaatg gagaagggtt ataaaattgc ccgcctgctc
     9361 cactttacga acaggaagaa gagaggatcc cacgaactga accccggaat catcagggcg
     9421 cagtcggttg caacagggat tcccctcatc cagagggact ttttctcgta tgaggaggaa
     9481 ttccggaagg tgatcctcga actccgggag cagggcgaga gaattgacgg ggcggttttt
     9541 gggcatatcc agacccacgg cagtctcgtg gagaggatct gccgggacct cgaccttgag
     9601 atcgtcatgc ccctctggaa aaaggattcg gaaagactcc tcgcggacat gatcgatgcc
     9661 ggtttcgaga ttgtcatcgc cagtaccagg gctgatgtgt tgggagaaaa atggctgggc
     9721 cggatcatcg atggagcgtt ccccggagag atccgcacgc tgggggtgcc tgtcgacccc
     9781 tgcggggaaa acggggagtt ccacacgctc gtgaccgacg gcccgatttt ccggaagaag
     9841 ataatcatca cccggtccga acctgccttt tttgacggtt actggtacat ggacatcagg
     9901 gatttttccc tgcaacagaa gggatgaggg ggagagcggg gggctgccct tttgggagga
     9961 gaaaagggcc gggttacgac cagatcgcat acattgatat gctgtttttc tgaagaaaac
    10021 tacatgtctc catatactcc atgcaataag atagagtaat atagacttcc gggcaggaga
    10081 acgggtatgg agattcggaa ggtgcaggta acaggagggt cttcctatgt gatcactctc
    10141 cccaaggaat gggtccaggc ccagaaaatt gcaaaaaacg agccactggg gatggtggtc
    10201 cagagtgacg gctcattgct cgttacgaag gagatcaacg aaaaaaccat ctcgcgggtc
    10261 aggaagatag acgtcactgc tatcgatgac cctacctacc tcttccggct cctcatcggg
    10321 atatacattg caggtttcac gaccatcgag ctcttttcga gaacacgtct cccgccgtcg
    10381 atagggttga tcgtgcggga ttttacccag gtggccatag gccccgagat cgtggaggag
    10441 accgacaacc ggatagttct caaggatctt ctcaacccta cggagatgcc ctttgataat
    10501 accctgaaga ggatgtacgt aatcgtcaag aacatgtacc tggacgccat gaatgccatg
    10561 gagacccgga atggaaaact catcgaggag ataatctccc gggacagcga cgtggaccgg
    10621 cttcactggc tcatcgcccg gcagagcagc atcgttctga aaaatcctga agtcgcgagg
    10681 aggatgggtg tcagtcccca catggtcatg aatgcgatga tcatcagccg gatcatcgaa
    10741 aggataggag accatgcggt acgctgggct gaaaatgcac gccagatcat tgatcacgat
    10801 ctcgacgcac ggattctcaa acacatgaag gatgcaagca cgcttgccct ttccatattt
    10861 gaccggagta tcactgcgta ttacaaggcc gatatccggg agtcacaccg gaacatcgag
    10921 caggtcagca cgctcgagga actttgcgag gagctgaacc agctcgtgat ggaagaggag
    10981 cctgatgttg ccgtcgcact ccggtacata tcggaaagta tccggagatc gggggaatat
    11041 gcaggggata tctccgagac ggtaatgaat tacctcgttg aagaaaaaat ctgaagcttt
    11101 tcgctccttt gatcgggtat tggaaagtga at
//
LOCUS       DAOOJU010000041        11125 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5333_length_11125_cov_15.754110, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000041 DAOOJU010000000
VERSION     DAOOJU010000041.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 11125)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11125)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11125
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5333_length_11125_cov_15.754110"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1061)
                     /locus_tag="PK679_08375"
     CDS             complement(<1..1061)
                     /locus_tag="PK679_08375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HPC56005.1"
                     /translation="MIPSLLCIPCRYFSSARPPSLDESRGIAIPCRPPGIRDAAGPAT
                     GSGRHGSGEALPSRGREGEVIPGMPPGTRDLRTPGEKADSLLIEIPLDSPLSGTEQEI
                     VAEIGRTCGKNGFFLEVDGSTFRFYVRSLDPRAFRSTVLDLLRTRGEQGGASPRLHRV
                     FGDLFDRIDAVRSYGIRGKKRIYATYNRERKVAGREGKVKARGPWYYARDHGFEREEN
                     ALPEEFRNRILPGDSEAVLKALPSQCVDIVITSPPYNFGLGYDTTADGIDWERYFAKL
                     FAVFDECIRVLKFGGRIIVNVQPLFSDYIPSHHIISRYFMDRRLIWKGEIIWEKNNYN
                     CKYTAWGSWKSPGNPYLKYT"
     gene            1182..1319
                     /locus_tag="PK679_08380"
     CDS             1182..1319
                     /locus_tag="PK679_08380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56006.1"
                     /translation="MQCITFDRSIEASRVLRICIAMATGDSLQETEREIRQIRESDDT
                     A"
     assembly_gap    1342..1441
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1524..2189)
                     /locus_tag="PK679_08385"
     CDS             complement(1524..2189)
                     /locus_tag="PK679_08385"
                     /inference="COORDINATES: protein motif:HMM:NF012304.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56007.1"
                     /translation="MSREHSAQVPGTGASPSPGEVFLSDLFLPSRRYRAAPAPSGHDA
                     GEGGWFSIMVDGSGDGHSIALFPGEEVFFSYERGASNNDAEFNAVILALENLPDHARA
                     RIHTDSQVVVWHLAAVSPRRPATYARKKARIQDLIATKDLEVEFRWIPRRENRADRFL
                     KNYIASLCGAGGAEPLHRRVRRLEVENLRLKARLAKAMKMLENRPVVIRDAGGYGMVP
                     EQQ"
     gene            complement(2357..3229)
                     /gene="hisG"
                     /locus_tag="PK679_08390"
     CDS             complement(2357..3229)
                     /gene="hisG"
                     /locus_tag="PK679_08390"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HPC56008.1"
                     /translation="MITIALPKGSLEEQTLLLFREADLEVRRTERDYNPVIEDARISK
                     VKILRPQEIPRFVEMGYFDLGITGLDWVKETGARVREVARLTYSKTGEGTVRIVVAVH
                     RDEPIDDARAIRPDSRVTTEYPELTREYFGRLGIPVRIFPSYGASEAKVPDLMDVVVD
                     LTETGSTLRKNGLKIIGQIMESYTVVIANRESFEDPGKRRAIEEIVTLLLGVIEARRQ
                     VLLSMNVPSSSMEKVVAVLPALKRPTVSRLHGVDYYSVQTVVHKKDVNTLIPGLKAAG
                     AEDILEIPITKIVR"
     gene            complement(3312..4598)
                     /locus_tag="PK679_08395"
     CDS             complement(3312..4598)
                     /locus_tag="PK679_08395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 family protein"
                     /protein_id="HPC56009.1"
                     /translation="MYEGDASEMVDIFRFAAVCPGPDLAPRVAAVPYDVVTRDEAAAS
                     IRDNPFCFLRVSRADAGLPGVSASDERVYARARETFESFLREGILSRDRTPGMYLYRV
                     TGNGNDFLGLACTVATRDYEENTIRRHELTRVEKEEDRTRHIDAVNAHTGPVVLLYVD
                     RNGLAAFLDSLWEKTGRVDLEVRAPDGTVHRIMRVTADADLAALEEAFAAVPRLYIAD
                     GHHRAKSAVNVAGKRKVEGRLTPEATRFLGVLFPHNGVKIHGYSRLVSDLSGMTPEEF
                     LGRLSERFSVEPRGEVDARAFHIPPLRVPAGAFHVFHVFLGGKWYECSRPRENGADVI
                     ASLDVSVLQREVLEPLLGIKDPRRDPRLQYLGGARPLADLMAMVLSGDYAVAFAMQPV
                     QVETVLAIADAGGIMPPKSTWFEPKLLSGLVVHTLD"
     gene            4654..5112
                     /gene="rimI"
                     /locus_tag="PK679_08400"
     CDS             4654..5112
                     /gene="rimI"
                     /locus_tag="PK679_08400"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012619231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HPC56010.1"
                     /translation="MLPEVTIRRARPGDIVHVARIEQESFPDPWSAAIFAETLSFFPE
                     TFFVAIAGDQVIGFVVGGLEDTGEEVYGHICNLAVDPAFRRQGIGRRLVAREEQQFAV
                     SLATGVQLEVRVSNKPAQAFYRRLGYRPVLRIAGYYANGEDAIVMMKWFG"
     gene            complement(5117..6322)
                     /gene="hmgA"
                     /locus_tag="PK679_08405"
     CDS             complement(5117..6322)
                     /gene="hmgA"
                     /locus_tag="PK679_08405"
                     /EC_number="1.1.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011449942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase (NADPH)"
                     /protein_id="HPC56011.1"
                     /translation="MDEYLERIKAGSLKLYALEQELPPAEAVALRRRYIEGETGVSLA
                     KVGSFSIGIDRVARKNCENMVGTVQVPVGVAGPLLVRGEYATGRYYLPLATTEGALVA
                     SVNRGCAAITRAGGAEVRILRDGMTRAPVFSTRSVAHAREVADWVASHPDEIARAAES
                     TTSHGKFLGATCTVVGTSVFVRMEFDTKDAMGMNMVTIGSEKAAEVISAATGARLVAL
                     SGNLCTDKKPAAVNVVRGRGRSVVAGVFLADDLIASVLKTDARSLVEVNTRKNLLGSA
                     AAGSLGFNAHAANVVAALFIACGQDPAHVVEGSLATTTADPAEGGVYVAVTLPDLPVG
                     TVGGGTGVETQAECLSLLGVAGSGDPPGTHARRFAEIVAAGVLAGELSLLSALAAQHL
                     ARAHKTLGR"
     gene            6425..7378
                     /locus_tag="PK679_08410"
     CDS             6425..7378
                     /locus_tag="PK679_08410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HPC56012.1"
                     /translation="MREQWCIRVPRAGAEQARQDLRSRGLLDMGLRPRQEGDWVLFPV
                     REACEGAVRGEFEPLPPPPDLPRHELIGGIAVLQDEDREGAERLLASRPSLHTALYPL
                     GDVEGEYRTRRFLVLAGKDTTETLYREHGLLFSIDLAEAYFSPRLSTERQRVLGLARP
                     GERVLDMFSGVGPFALTLARKASLVVACDLNPGAVRLLERNIRRNRARNVLPVFSDAA
                     RLPAILPWTFDRIVMNLPLGAARFLPVAASLSRPGTTVHVYALEEEEGQFLPAIRDAF
                     PVREVTERYVRSYAPGRWHAVYDVVVGEEERGKRGTGIARE"
     gene            7686..8231
                     /locus_tag="PK679_08415"
     CDS             7686..8231
                     /locus_tag="PK679_08415"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: protein motif:HMM:NF014021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HPC56013.1"
                     /translation="MIGELEKFVGNRVLGWFLAHPTSGAGINQLARELGVSAGSIKKY
                     VDIFIRDGILSKTRIGTLHLISLNNDDSIVQEMKRVYMAVVLREAGISSIAHNAVSLV
                     VYGSVASGTFDEKSDIDVLVLAKEPDVDYNRVAEIEEKVGHELQVTVIPYYRWEEMKK
                     QNDAFASGILARYIRFQGAEP"
     gene            8173..8646
                     /locus_tag="PK679_08420"
     CDS             8173..8646
                     /locus_tag="PK679_08420"
                     /inference="COORDINATES: protein motif:HMM:NF017020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEPN domain-containing protein"
                     /protein_id="HPC56014.1"
                     /translation="MLLHPESSPGTSVSRERSHELEVLHRRKSHPERSAGARPATIDA
                     ADRFLSSARRTCETGEYELALLAAYNSAFHCARALLFANGYTERSHACVILVLRHLFR
                     DDSRFLQFLATLDKMRISRHNVQYGVSRVTRGEAEFSIRFAGDFLQFVRERATPS"
     gene            8941..9543
                     /locus_tag="PK679_08425"
     CDS             8941..9543
                     /locus_tag="PK679_08425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HPC56015.1"
                     /translation="MIQLGTCSLGGGARVFDPVTIGFPSREFLGADTYPGTTIGKNAV
                     LRPGLIIYCQVAIGDDFQSGHNVLIREKMRIGNNVAIGSSSIIEGYGTIGDNVRIQSM
                     VFVPTHTTIGNGVFIGPAAVLTNDRYPPAGKPDLRGPEIRDNAVIGANATVMPGVTIG
                     EGAFVAAAAVVTRDVPPGKMAIGAPARIRDLPVAMRGTGP"
     gene            9540..10628
                     /locus_tag="PK679_08430"
     CDS             9540..10628
                     /locus_tag="PK679_08430"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HPC56016.1"
                     /translation="MIPVGKPSVAKEEENAVLRVLRSGMLAQGPETSAFEQEFARYCG
                     TAHAVAVSSGTAALHATLHALGIGKGHEAIVPSFTFFATASAVCMCGARPRFGDIDPD
                     TFNLSIGSVQDLLSSRTRAVIGVHLFGQPCDARPLREICDDEGIVFIEDAAQAHGAEY
                     HGKRVGGLGIAGCFSFYPTKNMTTGEGGIVTTDDAGLARKVRVFINHGQEEKYVHTCI
                     GYNYRMTDIAAAIGREQLKKLDAFNRRRQETAAYYDAHLPRDGIVCPFTAPGVTHVYH
                     QYVIRVTGGFRLTRDELAGYLRDRGIGTAVHYPVPLHRQPAFAAHARDARCPVAEECA
                     ATVLSLPVHPGVTGADRDRVCRTIAEVP"
     gene            10628..>11125
                     /locus_tag="PK679_08435"
     CDS             10628..>11125
                     /locus_tag="PK679_08435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HPC56017.1"
                     /translation="MDVGVIGVGVMGRNHVRVYSELKQAGDVYIYDQNRDAAMGVALA
                     HEAIFCATLEELLEKAEAVSVCVPTPFHRAVGEEVLAAGVHMLMEKPLCATAAEAESL
                     AGKVADGQVAGVGHIERFNPIVAEIRRIVRNPVFVELNRHNPASSRPMGSSVIEDLMI
                     HDLDIL"
BASE COUNT         2016 a         3465 c         3543 g         2001 t
ORIGIN      
        1 gtgtacttga ggtaggggtt gcccgggctc ttccagctcc cccaggcggt gtacttgcag
       61 ttgtagttgt tcttctccca gatgatctcg cctttccaga tgaggcggcg gtccatgaag
      121 taccgcgaga tgatgtggtg gctcgggatg tagtcggaaa agagcggctg gacgttgacg
      181 atgatcctcc ccccgaactt cagcacgcgg atgcactcgt cgaagacggc aaagagcttg
      241 gcaaagtacc gttcccagtc gatgccgtcc gcggtcgtgt cgtagccgag gccgaagttg
      301 tagggcggcg aggtgatgac gatgtcaacg cactgggacg ggagggcttt taagacggcc
      361 tcgctgtcgc cgggcagaat ccggttccgg aactcttccg gcagcgcatt ctcctccctt
      421 tcgaacccgt gatcgcgtgc atagtaccac ggcccgcgtg ccttcacctt gccctcgcgg
      481 ccggccacct tccgttcccg gttgtaggtg gcgtagatgc gctttttccc ccggatccca
      541 tagctcctca ccgcgtcgat ccggtcgaac aggtccccga acacccggtg caggcggggg
      601 gaagcgcccc cctgctctcc acgggtgcgg aggagatcga ggacagtgct cctgaatgcc
      661 cgggggtcga gtgaccggac gtagaaacga aaggtacttc cgtcaacctc gaggaagaat
      721 ccgttcttcc cgcaagtgcg gccgatttcc gcgacaatct cctgttcagt cccggagagg
      781 ggggaatcga gagggatctc tatcagcaga gagtccgcct tttctccagg ggtgcgtaag
      841 tcccgcgttc ccggcggcat accgggtatc acctccccct ccctgccccg cgaggggaga
      901 gcctccccgc tgccatggcg accagacccc gtcgcgggtc cggccgcatc ccggatgcca
      961 ggtggacggc aggggatggc aatcccgcgt gattcatcga gagaaggtgg acgtgcagaa
     1021 gagaaatacc tgcagggtat gcaaaggagc gaagggatca tcccccgctt ttcccccctg
     1081 tgtttggggg cggttcagac ctccggaccg gaagcctccc ggcagcttgc gtcgtatccc
     1141 cggaaacatt atttccgaac gaagggaaag accaagaatc catgcagtgc atcacgttcg
     1201 accgctccat cgaggcatcc agggtgctcc ggatatgcat tgcgatggca acgggtgatt
     1261 ccctgcagga gacagaacgg gaaatcagac aaatccggga aagtgatgat acggcgtgaa
     1321 ggtccttgtg aaccggtgaa tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nttcgtcccg gaaagcagag atcagcgttt cgatgggcgg gagaggcatt ctcccgcaag
     1501 gagcagtccc gcctgtccca tcctcactgt tgttccggga ccatgccgta cccgcccgcg
     1561 tcccggatga ccacgggccg gttctcgagc atcttcatgg ccttcgcgag gcgggccttc
     1621 agccggagat tctcgacctc gagccggcgg acgcggcggt ggagcggctc ggcaccccct
     1681 gccccgcaga ggctcgcgat gtagttcttc aggaaccggt cggcacggtt ctccctgcgg
     1741 gggatccacc ggaactcgac ctcgaggtcc ttcgtggcga tcaggtcctg gatgcgggcc
     1801 ttcttgcggg catacgtcgc aggccggcgg ggggagacgg cggcaaggtg ccagaccacg
     1861 acctggctgt cggtatggat ccgggcccgg gcatggtccg ggaggttctc gagggccagg
     1921 atgacggcat tgaactcggc atcgttgttg gaggcacccc gctcgtagga aaagaagacc
     1981 tcctcccccg ggaagagcgc gatactgtgg ccatccccgc tcccgtccac catgatcgag
     2041 aaccagcccc cttcccccgc atcgtggccg gatggtgcag gagctgcacg gtaacgccgg
     2101 gacggcaaaa agaggtcgga gagaaagact tcaccgggcg agggggaggc acccgtgcct
     2161 ggaacctggg cgctgtgctc cctgctcatc ctcctcaggt gatgtgttgc gcaatgacct
     2221 tatttaaatt ttttcatatc tcccaccctt tccgggcaca taaagggact cttttggtca
     2281 tcggggagaa taaaaaagaa taaaaaatgt tctgcgaaat aaaaatattc tgaccccttt
     2341 tcaaaaaagg ggctttttac ctcacgatct tcgtgatcgg gatctcgagg atgtcttctg
     2401 ccccggcagc cttgaggccc gggatcaggg tgttgacgtc cttcttgtgc acgacggtct
     2461 ggacgctgta gtagtcgacc ccgtgcaggc ggctcaccgt gggcctcttc agggcgggga
     2521 gaacggcaac caccttctcc atggacgacg agggcacgtt catcgagagg agcacctggc
     2581 gccgggcctc gatgaccccg agcaggaggg tcacgatctc ctcgatcgcc cgccttttgc
     2641 ccgggtcttc gaagctctcg cggttcgcga tcacgacggt ataggactcc atgatctggc
     2701 cgatgatctt gaggccgttt ttccggagcg tggacccggt ctcggtcagg tccacgacca
     2761 cgtccatcag gtcagggacc ttggcctcgg acgccccgta actgggaaag atccggaccg
     2821 ggatgccgag cctgccgaag tattcgcggg tcagttccgg gtactcggtc gtcacccggc
     2881 tgtcggggcg gatagcgcgt gcatcgtcga tgggctcgtc cctgtgcacc gcgaccacga
     2941 tgcggaccgt cccctcccct gtcttgctgt aagtgagccg ggcgacctcc cgcacgcggg
     3001 caccggtctc cttcacccag tcaagccccg ttatcccgag gtcgaagtag cccatctcca
     3061 cgaaccgggg gatctcctgg ggccgcagga tcttcacctt gctgatgcgg gcgtcctcta
     3121 tcaccgggtt atagtcccgc tcggtcctcc tgacctcgag atccgcctcg cggaagagga
     3181 ggagtgtctg ctcctcgaga ctccccttcg ggagtgcaat ggtaatcatg gtaccaggta
     3241 tgggaccggt aacgaaaaaa aggtctcccg gaccggggga aaaccccgca ggtccggcga
     3301 acggcgacga ttcagtccag cgtgtgcacg acaagccccg agaggagctt gggctcaaac
     3361 cacgtcgact tgggcggcat gatgcccccg gcgtccgcga tcgcgagcac tgtctcgacc
     3421 tgcacgggct gcatcgcgaa cgcgacggca tagtcgccgg aaaggaccat ggccatcagg
     3481 tccgcgagcg gccgggcacc gccgaggtac tggagccgcg ggtcacgccg cgggtctttt
     3541 atcccgagga gcggttcgag cacctcccgc tggaggacgg agacatcgag cgacgcgatc
     3601 acgtcggcgc cgttctcccg cggccggctg cattcgtacc atttcccgcc cagaaaaacg
     3661 tggaagacgt ggaatgcacc ggcagggacg cggaggggcg ggatgtggaa tgcccgggca
     3721 tccacctccc cgcgcggctc gaccgagaac ctctccgaaa gccgcccgag gaactcttcc
     3781 ggagtcatcc cggagaggtc ggagacgagc ctgctgtacc cgtggatctt caccccgttg
     3841 tgcgggaaga ggaccccgag gaaccgggtc gcctccggcg tcaggcgtcc ctccaccttc
     3901 cgctttcctg ccacgttgac ggccgacttt gcccggtggt ggccgtcggc gatatacagg
     3961 cgcgggacag ccgcaaaggc ctcctcgagg gccgcaaggt ccgcatcggc cgtcacccgc
     4021 atgatgcggt ggaccgtccc gtccggggca cgcacctcga ggtccacccg tcccgtcttt
     4081 tcccagagag agtcgagaaa tgccgcaagc ccgttccggt cgacgtagag gaggacgacg
     4141 gggcccgtgt gggcattcac cgcatcgatg tgccgggtcc ggtcctcctc cttctccacg
     4201 cgggtgagct cgtgccggcg gatggtgttc tcctcgtagt cccgggtcgc gaccgtgcag
     4261 gcgaggccca ggaagtcgtt gccgtttccc gtcacccggt agaggtacat gccgggtgtc
     4321 ctgtcccgcg agaggatccc ctcacgcagg aacgattcga atgtctcgcg ggcccgtgcg
     4381 taaaccctct cgtccgaggc gctgaccccc gggagcccgg catccgcccg gctgacacgc
     4441 aggaaacaga aggggttgtc gcggatggag gcggccgcct cgtcccttgt caccacgtcg
     4501 tacgggaccg cggcgacccg cggtgcgagg tccggaccgg gacacaccgc tgcaaaacga
     4561 aagatatcca ccatctctga cgcgtctccc tcatacattc tccctcgcag tatattagag
     4621 caatgaagaa cataggggag atcacagggt cacatgctcc cggaggtcac catccgcagg
     4681 gcacggccgg gggacatcgt gcacgtcgcc cggatcgagc aggagtcatt ccccgacccg
     4741 tggagcgccg ccatctttgc cgagacgctc tcgttcttcc ccgagacctt cttcgttgcc
     4801 attgccggcg accaggtcat cgggttcgtc gtcggaggcc tcgaggacac cggggaagag
     4861 gtctacggcc acatctgcaa cctcgccgtg gacccggcgt tccgcaggca ggggatcggc
     4921 cgccggctcg tcgcacggga agagcagcag tttgccgtca gccttgcgac cggtgtccag
     4981 ctcgaggtcc gcgtctcgaa caagccggca caggccttct accggcggct cgggtaccgg
     5041 ccggtcctcc gcatcgccgg gtactacgcc aacggcgagg acgcgatcgt gatgatgaag
     5101 tggttcgggt gaggccctac cgcccgagcg tcttgtgtgc ccgggcgagg tgctgggcgg
     5161 cgagtgccga gaggagcgag agttcgccgg caaggacacc ggcagccacg atctcggcaa
     5221 acctgcgggc atgcgtcccc ggggggtcgc cgctcccggc aaccccgagc agcgagaggc
     5281 actcggcctg cgtctcgacg ccggtccccc cgcccaccgt cccgaccggg aggtcgggga
     5341 gggtgacggc aacgtacacg cccccctcgg caggatcggc ggtcgttgtc gcgaggctgc
     5401 cctccaccac gtgggccggg tcctgcccgc aggcgatgaa gagggcggcc accacgtttg
     5461 ccgcgtgggc gttgaagccg agcgacccgg ccgccgcaga cccgaggagg ttctttcgcg
     5521 tgttcacctc gacgagggag cgggcatccg tcttgaggac cgaggcgatg agatcgtcgg
     5581 cgagaaacac ccccgcgacg acgctgcgcc ccctcccccg gacgacgttg acggcggcag
     5641 gtttcttgtc ggtgcagagg ttgccggaga gggcaacgag ccgggctccc gtcgcggcac
     5701 tgatcacctc tgctgccttc tcgctcccga tggtgaccat gttcatcccc atggcgtcct
     5761 ttgtgtcaaa ctccatccgg acaaagacag acgtcccgac gaccgtgcag gtcgcgccaa
     5821 ggaacttccc gtgggacgtg gtggactcgg cggcacgggc gatctcgtcg ggatgggagg
     5881 cgacccagtc ggcgacctcg cgggcgtggg caacgctccg ggtcgaaaag acgggtgccc
     5941 gcgtcatccc gtcgcggagg atgcggacct ctgcaccccc ggcccgcgtg atcgcggcgc
     6001 acccgcggtt caccgaggcg acgagcgccc cctcggtggt cgcgagcggc aggtagtacc
     6061 tgcctgtcgc gtattccccg cggacgagga ggggcccggc aacgccgacg gggacctgga
     6121 ccgtccccac catgttctcg cagttcttgc gtgccacccg gtcgatcccg atcgaaaacg
     6181 accccacctt cgcaagcgac acccctgtct ccccctcgat gtaccgccgc cggagggcga
     6241 cggcctctgc cgggggcagt tcctgctcga gggcgtagag cttgagcgag cctgccttta
     6301 tccgctccag atactcatcc atgtaccacc atgggggcgg gtggtgcata acctttcttt
     6361 ccgggagaga caccatccct tttccctgca aaagtcccag gagtaataag aacggaggga
     6421 cgggatgagg gagcagtggt gcatccgggt gcccagggca ggggcagagc aggcccggca
     6481 ggatctccgg tcccgcgggc tcctcgacat gggtctccgg ccccggcagg agggggactg
     6541 ggtcctcttc cccgtccggg aggcgtgcga gggggctgtc cggggagagt tcgagcccct
     6601 gcccccgccc ccggaccttc cccggcacga gctgatcggg gggatagcgg tcctccagga
     6661 cgaagacagg gaaggtgcag aacgcctcct tgcctcccgc ccctccctcc acacggccct
     6721 ctatcccctc ggcgatgtcg agggggagta caggacgcgg cggttcctgg tccttgccgg
     6781 gaaggacacg acagagaccc tctaccgcga gcacggcctc ttgttctcga tcgaccttgc
     6841 cgaagcctac ttctcgcccc ggctctccac ggaacgccag cgggtcctcg gcctcgcgag
     6901 gcccggcgag cgggttctcg acatgttctc cggcgtggga ccgtttgccc tcaccctggc
     6961 ccggaaagca tccctggtcg ttgcgtgcga cctcaacccc ggtgccgtcc ggctcctgga
     7021 aagaaacatc cgccggaacc gggcccggaa cgtgctcccc gtcttttccg atgcggcacg
     7081 cctccccgcc atcctcccgt ggacgtttga ccggatcgtg atgaacctcc ccctcggggc
     7141 tgcccggttc ctccctgtgg cagcctccct ctcccgcccg gggacgaccg tccatgtcta
     7201 tgccctcgag gaggaggaag gtcagttcct ccccgcgatc cgggatgcat tccccgtcag
     7261 ggaggtcacg gagcgctacg tccggtccta tgcacccggg cggtggcacg cggtgtacga
     7321 cgtggtggtg ggggaggagg aaagggggaa acgggggacg ggaattgccc gggagtgaca
     7381 atcgccggga agaaggaatg gcgtggaatc tttttctgcc ccggaagact ggctggcttt
     7441 ttctttaatg gtcaaggacc ccttcggtgt ccatgtccct cgcctgatgg agagggagat
     7501 cgcggagacc tgccacctgt gtccatgcac tatccggatg gaaggtcacc agtccacacg
     7561 gaaacctacc cgggggaacg ctgccacacc cgggtgagac cttccggccg gaaaggtgtg
     7621 tggctttatc ccgtcatttc aatgaataat tatataatag gttgaatgat cattcaatta
     7681 attgaatgat tggcgagttg gaaaagttcg tgggcaacag ggtgctggga tggtttcttg
     7741 cgcatccgac gtcgggtgca ggtattaacc agctcgcccg tgaactgggg gtctcggcgg
     7801 ggagcatcaa aaagtatgtt gacatcttca tccgggacgg tatcctgtcg aagaccagga
     7861 taggcacgct gcatctcata tccctgaata atgatgacag tatcgtgcag gaaatgaagc
     7921 gggtatacat ggcggtcgtt ctccgcgagg caggcatctc gtctatcgca cataatgccg
     7981 tttccctggt tgtctacggc agcgtggcat ccggcacctt cgatgaaaag agtgacatcg
     8041 atgttcttgt ccttgcaaaa gagcctgatg tcgattacaa ccgggttgct gagatcgagg
     8101 aaaaggtcgg tcatgaactc caggtcaccg tgattcccta ttaccggtgg gaagagatga
     8161 agaagcagaa cgatgctttt gcatccggaa tcctcgcccg gtacatccgt ttccagggag
     8221 cggagccatg aactggaagt cctgcatcga cgaaaatctc atccggaacg atccgcgggc
     8281 gcaagaccgg caacgatcga tgccgcggac aggttcttat catcagcacg caggacatgt
     8341 gagactggag aatatgaact ggccttgctc gccgcatata acagtgcatt ccactgtgca
     8401 agggccctcc tctttgcgaa cgggtatacc gaacggagcc atgcatgcgt gatcctcgtg
     8461 ctccgccatc tcttccggga cgatagccgc ttcctgcaat tccttgccac actggataaa
     8521 atgcggatct cgcggcataa tgtccagtac ggtgtcagca gggtcacccg cggggaggca
     8581 gaattttcca tccggttcgc gggagatttt ctccagtttg tcagggagag ggccaccccc
     8641 tcatagaacg ggcaccggca gtcatctaat ccggcagtcc ggtacacgtg cctgcccgtg
     8701 caacgggaca gacatgtgag attcacgaca tccgggtgcc ctttttccgg ccacaaaaag
     8761 gggctctctt gtcgccgttc gaaccggggg actgcaggtg gcgccggcag gaatacctcc
     8821 cggagtaacc cattgttcgg gaggttgacg actctctgca ggggcacttt gtcctgccac
     8881 aagcattatc tccctttatc tgatacatat acgaaaaagg acagtattcg ggggattttt
     8941 ctgatccagc tcggcacatg ttccctgggc gggggggcac gggtctttga cccggtcacg
     9001 atcggctttc cctcccgcga gttcctcggg gccgatacct atcccggcac gacgattggg
     9061 aagaacgccg tcctgcggcc gggcctcatc atctactgcc aggttgcaat cggtgacgat
     9121 ttccagtcgg gacataacgt tttgatccgc gaaaagatgc ggatcgggaa caacgtcgcc
     9181 atcgggtcat cctccatcat cgaggggtac gggaccatcg gggacaacgt gcggatccag
     9241 agcatggtct ttgtcccgac gcacactacc atcgggaacg gcgtcttcat cgggccggcg
     9301 gcggtcctga ccaacgatcg gtatcccccg gcgggaaaac cggacctgag gggacccgag
     9361 atccgggaca atgccgtgat cggggccaat gcaacggtca tgcccggtgt caccatcggg
     9421 gagggggcat tcgttgctgc agcagcggtc gtgacacggg acgtgccgcc cggaaagatg
     9481 gcaatcggtg caccggcccg catccgggac ctcccggtcg ccatgagggg gaccgggcca
     9541 tgataccggt gggaaagccg tctgtcgcaa aggaagagga gaatgccgtc ctccgggtgc
     9601 tccggtcggg aatgctcgcc cagggtcccg agacgagcgc gtttgagcag gagtttgccc
     9661 ggtactgcgg gactgcccat gccgttgccg tcagttccgg gacggcagcc ctccatgcga
     9721 ccctgcacgc actggggatc gggaaggggc acgaggcgat cgtcccgtca ttcaccttct
     9781 ttgcgaccgc gtcagcggtc tgcatgtgcg gggcgaggcc ccggttcggg gacatcgacc
     9841 cggacacgtt caacctgtcg atcgggagcg tccaggacct gctctcgtcc cggacccgtg
     9901 ccgttatcgg ggtccacctg ttcggccagc cctgcgatgc acgacccctg cgggagatat
     9961 gcgatgacga gggaatagtc ttcatcgagg acgcggccca ggcccacggt gcagaatacc
    10021 atggaaagag ggtgggagga ctcggcattg ccgggtgttt ctccttttac ccgacgaaga
    10081 acatgaccac cggggagggg ggaatcgtga ccacggacga tgccgggctt gcccggaaag
    10141 tccgggtctt tatcaaccac gggcaggagg agaagtacgt gcacacctgt atcgggtata
    10201 actaccgcat gaccgacatc gcggcggcaa tcgggaggga acagctgaag aaactggatg
    10261 cgttcaaccg gcgccgccag gaaactgccg cgtactacga tgcgcacctg ccccgcgacg
    10321 ggatcgtctg cccgtttacg gccccgggcg tcacgcacgt gtaccaccag tacgtcatca
    10381 gggttaccgg cgggttccgc ctcacccggg acgaactggc aggctatctc cgggacaggg
    10441 gtatcgggac ggcagtgcac tacccggtcc cgctccacag gcagccggcg tttgcggcac
    10501 atgcacggga tgcccggtgc ccggtggcag aggaatgtgc tgcgacagtc ctctccctcc
    10561 cggtccaccc gggagtgacc ggtgccgacc gtgaccgtgt ctgcaggacg atagcggagg
    10621 tgccgtaatg gacgtcggtg tcatcggggt cggcgtcatg ggaaggaacc acgtccgcgt
    10681 gtactcggag ctgaagcagg caggggatgt ttacatctac gaccagaaca gggatgcagc
    10741 gatgggtgtt gccctcgcac acgaggcgat tttctgcgca acgctggaag agctcctgga
    10801 aaaggccgaa gccgtcagcg tctgcgtccc gacaccattt cacagggcgg tgggcgagga
    10861 ggttcttgcc gccggcgtgc acatgctgat ggaaaagccg ctctgtgcca ctgcggcaga
    10921 ggcagagagt ctcgcaggga aggtggcgga cggccaggtc gccggggtgg ggcacatcga
    10981 gcgcttcaac ccgatcgttg ccgagatccg ccggatcgtc cgcaaccctg tcttcgtgga
    11041 gttaaacagg cacaaccccg cgtcctcgcg tcccatgggg tcctcggtca tcgaggacct
    11101 gatgatccat gacctcgaca tcctc
//
LOCUS       DAOOJU010000042        11024 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5389_length_11024_cov_16.110676, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000042 DAOOJU010000000
VERSION     DAOOJU010000042.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 11024)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11024)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11024
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5389_length_11024_cov_16.110676"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            64..342
                     /locus_tag="PK679_08440"
     CDS             64..342
                     /locus_tag="PK679_08440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L44e"
                     /protein_id="HPC56018.1"
                     /translation="MKMPQKFRTYCPFCRAHQTHEVEKVKKSKTSGLHWIDRQKARRS
                     TVGNMGKFSKVPGGDKPTKRVNVRYRCSACGKAHLRPGFRAGKFELKE"
     gene            348..536
                     /locus_tag="PK679_08445"
     CDS             348..536
                     /locus_tag="PK679_08445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S27e"
                     /protein_id="HPC56019.1"
                     /translation="MVQQIRENRSRFFKVKCPDCENEQVVFEKASTRVDCIVCGRVLS
                     EPAGGKARLQAEILATFE"
     gene            547..1332
                     /locus_tag="PK679_08450"
     CDS             547..1332
                     /locus_tag="PK679_08450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 subunit
                     alpha"
                     /protein_id="HPC56020.1"
                     /translation="MSERDWPENGELVVCTVKDVKDFAAFVNLDEYPGRVGLIPISEV
                     ATGWIKYIRDHIREGQKVVCKVLHVDPSRGHIDLSLKDVNEHQRREKIREWKNESKAR
                     KWIGFAAAAAGEKAEDLEAAIYSRYGDLYSVFEDIVTGEDALASLPVSAAAKAALEQV
                     ARENVKIPRVTVSGTLVLTSSKPDGVNIIRRALRSAEPKIPGVDIELTYLGAPNYRIK
                     VTAGNYKAAEKAIEKAASAAIGVIERAGGEGRFVRKPKSGKVA"
     gene            1329..1490
                     /locus_tag="PK679_08455"
     CDS             1329..1490
                     /locus_tag="PK679_08455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-protein complex protein Nop10"
                     /protein_id="HPC56021.1"
                     /translation="MSGRLRRCPRDRTYTLKFSCPVCGHPTVPAHPARFSPSDSLGRY
                     RRIARGWTI"
     gene            1478..2230
                     /locus_tag="PK679_08460"
     CDS             1478..2230
                     /locus_tag="PK679_08460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome assembly chaperone family protein"
                     /protein_id="HPC56022.1"
                     /translation="MDDITVRFTDGDGSGIRAPVLIEGLPGIGHVGKLVAEHMIHELA
                     ARKVAEIESIYFPPQVIIRENGTIRLANNELYYAGSGDKRFLFLVGDFQSTSGEGHYL
                     LADTYVSLALELGVRRIYTLGGYGVGHLVDVPRVLGAVNREDLREEVEAAGAVISPDE
                     PGGGIIGAAGLLLGLGLSRGIEGICLMGETSGYLVDPKSAARVLSVLCTLLGIEVNAT
                     TLEERGREMEHMIERLVDTERSMREDELRYIV"
     gene            2239..3363
                     /locus_tag="PK679_08465"
     CDS             2239..3363
                     /locus_tag="PK679_08465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease Q family protein"
                     /protein_id="HPC56023.1"
                     /translation="MDLSCDLHIHSCFSIATSRRMVPPLILEACRTKGLDVIGSGDAL
                     HPEWRRMWEEALSRTGDCGTCVVPSAEIEDKNRVHHLVLMEDFASFRDLALDLAPSAP
                     GLGSTGRPRVPLTGGEIARLVHRRDGLIGPAHAFTPWTSLYAAHDSLESCYGSEHVDF
                     LELGLSADSSYGAAIPHLSRIPFISSSDAHGPDPCRLGREFVVLSAPEGTPSAVLDAL
                     RQGNVVRNVGFFPEEGKYNRTACTRCYHQFPADDALSCSWKCPLCGGRIKKGVRDRAR
                     ELSSGPALPRPPYLHMIPLAEILARVLPVSSVRARAVCTLYDRFIGAFGNEISVLTEI
                     PVQELSDIHPGAAAAVGSLRSGRVRLSPGGGGRYGTFSFF"
     gene            3453..3635
                     /locus_tag="PK679_08470"
     CDS             3453..3635
                     /locus_tag="PK679_08470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HPC56024.1"
                     /translation="MLHVLRDVCGYCGCCVSVCPEGALELIDAYLEIGDNCTGCGICA
                     KVCPLGALEVKDETPV"
     gene            3619..4815
                     /locus_tag="PK679_08475"
     CDS             3619..4815
                     /locus_tag="PK679_08475"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012107515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC56025.1"
                     /translation="MKPRYDLLVIGGGPGGAVAAETAAKAGLSVLLAEKRPAIGAPVR
                     CAEGIGRESLTEFVEPDPCFISAELKGAEIVAPDGSSLKLNSERAGNKVGYILDRKVF
                     DRELVWRAAEAGADVAVKTRASAPILENGAVKGAVLHHCGETRRVGADIVIAADGVES
                     KFARWCGIDTTVPVREIMTSAQYLMTDIDIDPTVTVFYVGNSVAPQGYLWVFPKGERS
                     ANVGIGISGAKSGAGHRARDYLDRFVASRFPEGKTIEHIVGGVSVCQPLACTVSDGLM
                     IVGDAARVVDPLTGGGIYNAMFTGRLAAQTAVSAIRNGKCSKNVLMAYDRGWRESPMG
                     KTIARNWHLKEYFIRMTDEKFNALISSASTMNLEEFSTLNLVKELVKRNPLLLGDLAK
                     LSFLLR"
     gene            complement(4804..5472)
                     /locus_tag="PK679_08480"
     CDS             complement(4804..5472)
                     /locus_tag="PK679_08480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HPC56026.1"
                     /translation="MYIIIVGLGGIGRSLTQLAVEHGNNVVIIDRDEQRCSEILEHYD
                     VLAVTGNATDKSILEDAGIDRADALVATTSDDSVNLMTCWLAKRFKVPTVVSIVNQKE
                     HSDLFSEVGVKISENPDELVAQRLYYWAENPQMQQLASIPGGTIFEVVAEKGAPIVDH
                     EIRELKVKDFVFIAIRRAGGELIIPSGNVKIRPGDTITVFTKKEAEDECLAILNKQLR
                     ASPK"
     gene            5532..6167
                     /gene="rnhB"
                     /locus_tag="PK679_08485"
     CDS             5532..6167
                     /gene="rnhB"
                     /locus_tag="PK679_08485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HPC56027.1"
                     /translation="MLCGVDEAGKGAVLGPLVVAAVGCGKKEDLADLGVRDSKELSPQ
                     RREALAGEIRRSFPVAVLSLSPAEIDGRGIGLNTLIARSHAAVISMLAPSVAVVDACD
                     VNASRYGGMVTGFLSVPCRVVSCHHADRQHPAVSAASIVAKVERDSMIHRLHDEWGSF
                     GSGYPSDPVTIRFLERYLEEKGEIPPIARKSWETTRTILARAEQRDLLKFL"
     gene            6258..7613
                     /locus_tag="PK679_08490"
     CDS             6258..7613
                     /locus_tag="PK679_08490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012617635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HPC56028.1"
                     /translation="MHWLFWVVLALLLYTVAAGYIYLRKAAYEREKADRIAFPEEGTR
                     EKSVWDSIVFYGPVLAIKTDRVGFFDRYIRYTPILRVYATLGVVMVALISAGIAAILF
                     LSVRLTFLFRPEPTGIYAPQNIFLIPGINEYVPSTVAVWFAFVLTIAIHEWGHGILCR
                     VENITVRSMGALVAVIPIGFFVEPDEQELEKSRGMPKIRMFGAGITNNIVVGTICFVA
                     LILLFGMVVPTGNPVIAGVYKNYSAWDAGVPAPSVITAVNGIPVASRDDVSRILNATR
                     PGDQVTLTLDAGGEVRDYALVLSEWPEELGLHHSGFMGISYYDGAAIKEGVRESLSFP
                     GLIRFLTIPFDPTAAGQALRVLAFETPETRFYEEPFPGFWGLVHVLFWCAWININVGI
                     FNAIPMVPLDGGYILKEGVERLFERWGLSKYAIPVVSLVSSVMVVMLLALVLLPYLLH
                     I"
     gene            7746..8960
                     /locus_tag="PK679_08495"
     CDS             7746..8960
                     /locus_tag="PK679_08495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-related McrA-glycine thioamidation protein"
                     /protein_id="HPC56029.1"
                     /translation="MILRPCKKLYNNETQRTTSPEETLARVEKALPAAGITRVADITN
                     LDRLGIPVFSSIRPTAGRGAISVYNGKGATPTEARVSAIMEGIERYSAEVPPGTTLPL
                     ARYPDVAGDVPVLDPADLILPRGKDPRMTIPWIGGYDILQEEEILVPASAVFHPLPET
                     YPQLFRTSTNGLASGNTLEEAVFHALMEVIERDAWSLVEASRDTGPRVTAIGDSLPAS
                     LLSRFASAQVEVHVRDITSDLGIPTFAAVSDDLQLRDPALLTIGMGTHTSARIALLRA
                     LTEVAQSRLTQIHGAREDTDTADLRRRAGYERVRRMNAYWFDGKSEEPFDQIPSFDTD
                     DFLSDIRIALDRIRRAGMERVIVVDLTRPEIGVPVVRVIVPGLEVYAMDPQRAGGRCR
                     DARNRRFSRSQL"
     gene            8920..9588
                     /locus_tag="PK679_08500"
     CDS             8920..9588
                     /locus_tag="PK679_08500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfuA-related McrA-glycine thioamidation protein"
                     /protein_id="HPC56030.1"
                     /translation="MTHGIVVFLGPSCDRSVAGRIVAADYRPPAARGDITSAAAGGAR
                     IITLIDGVFFQECAVGHREIVAALSQGIRVIGASSMGALRASELHTLGMEGVGLIYRL
                     YRDGRLVSDDEVALVYDPETYCALSEPLINIRCTLREARNAGIITGTEERELLASARS
                     LYFPERTYALVCRHAGEKIPGETCQRFLEFARSHAVDQKREDAIAALRRTREVALEAG
                     ILKE"
     gene            complement(9644..10282)
                     /locus_tag="PK679_08505"
     CDS             complement(9644..10282)
                     /locus_tag="PK679_08505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC56031.1"
                     /translation="MYTIMVIDDSPFIVDIFVTMLQRGGYQTVAAYGGQEALDLLQTV
                     KPDLILLDIMMEPMDGWETLMHIKNDHRIRDIPVIMLTAKQLTPNEAQEYGIYIEDYI
                     MKPITHKELYEAIEAQLNRRRVLEKDLEMAREAGVDEAVIQNYKRLQRSIDINKRLLK
                     ILENTYRTSEAREEEGEDDFSMAIRNMEMNVRYQEEQLNSLRSSFMNRTASA"
     gene            complement(10285..10644)
                     /locus_tag="PK679_08510"
     CDS             complement(10285..10644)
                     /locus_tag="PK679_08510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="HPC56032.1"
                     /translation="MLKEKVKAYIEKVRAIDGVKGCALVSRDGIMLGQSLERDFNEPW
                     LAAMCATLFASAESASGILKMAPPEYVCVHGGAHSLVVLGAGDKILIVVVAERGFEHS
                     PGARMLEIIASEIGGSF"
BASE COUNT         2125 a         3415 c         3296 g         2188 t
ORIGIN      
        1 tcttaaatat caacccgggc aaataatact gatattcgat atccggaata agaggccgat
       61 tccatgaaaa tgccacagaa attcaggaca tactgcccgt tctgccgggc tcaccagacc
      121 cacgaggtgg agaaggtcaa gaagagcaag acctcgggtc tgcactggat cgacaggcag
      181 aaggcacgga ggagcacggt cgggaacatg gggaagtttt ccaaggtccc cggcggtgac
      241 aagccaacga agagagtaaa cgtccggtac cggtgcagtg cctgcggaaa agcacacctg
      301 cgtcccggtt tccgcgccgg caagttcgag ttgaaggagt aaacagcatg gtccagcaaa
      361 tccgggagaa ccgcagcagg ttcttcaagg tcaagtgccc tgactgcgag aacgagcagg
      421 tcgtcttcga gaaggcgagc acgagggtcg actgcatcgt ctgcggaagg gtcttatcag
      481 agcctgccgg cggaaaggca aggctccagg cagaaatcct tgcgacattc gagtgatgtg
      541 tcaccgatga gcgagagaga ctggccggaa aacggggaac ttgtcgtctg cactgtgaaa
      601 gacgtcaagg actttgccgc ttttgtcaac ctcgacgagt accccgggcg cgtcgggctt
      661 atccccatct cggaggtggc aaccggctgg atcaagtata tccgcgacca catccgcgag
      721 ggccagaaag tcgtctgcaa ggtgctccac gtcgatccgt cacgcgggca catcgacctc
      781 tcgctcaagg acgtcaacga gcaccagcgc cgcgagaaga tccgggaatg gaagaacgag
      841 tccaaggcac gcaagtggat cggctttgcc gctgccgccg ccggcgagaa ggcggaagac
      901 ctcgaggcag cgatatactc ccgttacggc gatctctatt ccgtttttga ggatatcgtt
      961 accggggaag acgccttggc gtcccttccg gtctccgcgg ccgcgaaggc tgcactcgaa
     1021 caggtcgccc gggaaaacgt caagataccg cgtgtgactg tcagcgggac gctcgtcctc
     1081 acatcgagca agcccgacgg tgtcaacatc atccggaggg cgcttcgttc tgcagaacca
     1141 aagataccgg gtgtcgacat cgagctcacg tacctgggtg cacccaacta ccgcatcaag
     1201 gtgaccgcag gcaactacaa ggcagcggag aaggccatcg aaaaagctgc ctcggctgcc
     1261 atcggagtca tcgaacgggc cggtggcgag ggccggttcg tgaggaaacc caagtccggg
     1321 aaggttgcat gagtggccgg ctgaggcgct gcccgcggga ccggacgtac acgctgaaat
     1381 tctcctgtcc tgtctgcggc caccccaccg tgccggcgca tcctgcacgt ttttctccct
     1441 ccgacagcct gggccggtac aggaggattg cacgaggatg gacgatataa ccgtcaggtt
     1501 cacagacggg gacggatccg ggatccgcgc ccccgtcctc atcgaggggc tgcccgggat
     1561 cgggcacgtg ggaaagctcg ttgcagagca catgatccac gagcttgcgg cacggaaggt
     1621 cgccgagatc gagtccatct actttccccc ccaggtcatc atcagggaga acgggacaat
     1681 ccggctcgca aacaacgaac tctattacgc cgggagcggg gataagcggt tcctcttcct
     1741 cgtcggggac ttccagagca cgtcaggcga aggccactac ctgcttgccg acacgtacgt
     1801 ctccctcgcg ctggagctcg gggtcaggag gatctatacc ctcgggggat acggtgtcgg
     1861 tcacctcgtt gacgtccccc gcgtgctcgg cgcagtcaac cgcgaagacc tccgggagga
     1921 agtcgaggct gctggtgcgg tcatcagccc tgacgagcct ggcggcggga taatcggggc
     1981 ggcgggtctc ctgctcggcc tcggcctttc ccgcgggatc gagggaatct gcctcatggg
     2041 tgaaacgagc gggtacctcg tggacccaaa gagcgctgcc cgggtcttga gcgtgctctg
     2101 caccctcctt ggtatcgagg tcaatgccac gacgctcgag gagaggggcc gggagatgga
     2161 gcacatgatc gagagactgg tcgacacgga gcgcagcatg cgcgaggatg aactcaggta
     2221 catcgtctga agagatgcat ggacctctcc tgcgacctgc acatccattc ctgcttctcg
     2281 attgccacct cgcgcagaat ggtcccgccc ctcatcctgg aagcctgcag gacgaagggg
     2341 cttgacgtca tcgggagcgg cgatgccctc cacccggaat ggcggaggat gtgggaggag
     2401 gcactctccc gcaccgggga ctgcggcacc tgcgttgtcc cctctgccga gatcgaggac
     2461 aaaaaccgcg tccaccacct cgtcctcatg gaggactttg cctcgttccg ggaccttgcc
     2521 cttgaccttg caccctctgc accgggtctt ggatcaacgg gacgaccgcg ggttcccctc
     2581 accggcgggg agatagcacg gctggtgcac aggagggacg ggctgatcgg gcccgcccac
     2641 gcgttcacgc cgtggacttc gctctacgcg gcccatgaca gcctggaatc gtgttacggg
     2701 agcgaacacg tcgatttcct cgaactcgga ctctcggcag acagttccta cggtgccgca
     2761 atcccccacc tctcgcgtat ccccttcatc tcgagctccg atgcccacgg gcccgatccc
     2821 tgccggctgg gcagggaatt cgtcgtcctc tccgcccctg aggggacgcc ctccgccgtg
     2881 ctcgatgcac tcaggcaggg aaacgtcgtc cgcaacgtcg ggttcttccc ggaagaggga
     2941 aaatacaacc ggacggcctg cacgcggtgc taccaccagt ttccggcgga tgacgccctt
     3001 tcctgttcct ggaagtgtcc cctctgcggg ggaaggataa agaagggggt acgtgaccgg
     3061 gcccgcgagc tctcgtccgg gcctgctctc ccccggccac cctacctgca catgatcccc
     3121 ctcgccgaga tccttgcacg ggtgctcccg gtctcctctg tccgggcacg ggctgtctgt
     3181 accctctacg accggttcat cggggcattc gggaacgaga tctccgtgct gacggaaata
     3241 cccgtgcagg agctctcgga cattcatccc ggggccgccg ctgcagtcgg atccctccgg
     3301 tccgggaggg tgcgcctctc tcccgggggt ggggggaggt acgggacatt ctcgtttttc
     3361 tgaccggcac atttccccgt taagccacgg aaatacccca aaatccggat tcatgcaaag
     3421 attttagggt atcggacaca tacagtaccg ggatgttgca cgttctccga gatgtatgcg
     3481 ggtattgcgg gtgctgtgtc tcggtctgcc cggagggtgc gctcgagctg atcgacgcat
     3541 acctcgaaat cggtgacaac tgcacgggat gcggtatctg tgcaaaggtg tgccccctcg
     3601 gtgccctgga ggtgaaggat gaaaccccgg tatgatctcc tcgtcatcgg cggcggtccg
     3661 ggtggggcgg ttgctgcaga aacggccgca aaggcgggcc tgtccgtcct gctggcggag
     3721 aaacgcccgg caatcggtgc cccggtccgg tgtgccgaag gaataggcag ggaatctctc
     3781 acggagttcg tcgagcccga cccgtgtttc atctcggcgg aactgaaagg tgcagagatc
     3841 gtcgcacccg acggatcatc gctgaagctg aactcggaga gggcaggcaa caaggtgggg
     3901 tacatcctcg accgcaaggt ctttgaccgg gagctcgtct ggcgggcagc ggaagcgggc
     3961 gcggacgttg ccgtcaagac gcgggcatct gcacccatcc tcgaaaacgg tgccgtgaag
     4021 ggtgccgtcc tccaccactg cggcgagacg cggcgggtcg gggccgacat cgtgattgcc
     4081 gcggacggtg tcgagtcgaa gttcgcgcgg tggtgcggga tcgatacgac tgtccccgtc
     4141 cgggagatca tgacgtctgc ccagtacctc atgaccgaca tcgatatcga ccccaccgtc
     4201 acggtcttct acgtcggcaa cagtgtcgct ccccagggct acctctgggt ctttcccaag
     4261 ggggaacggt ctgcgaacgt cggcatcggc atcagcgggg caaagagtgg cgcagggcac
     4321 cgtgcacgcg actacctcga ccggttcgtt gcctcccggt ttccggaagg aaagaccatc
     4381 gagcacatcg tggggggtgt ttccgtctgc cagcccctcg cctgcacggt ctctgacggg
     4441 ctcatgatcg tcggtgacgc ggcaagggtt gtcgatcccc tgaccggcgg cgggatctac
     4501 aacgccatgt tcacggggcg gctcgctgca cagaccgcgg tatccgccat ccggaacgga
     4561 aagtgctcaa agaatgtttt gatggcatac gacaggggat ggcgcgagtc cccgatggga
     4621 aaaaccatcg cccggaactg gcacctgaag gagtatttca tccggatgac ggacgagaaa
     4681 ttcaacgcgc tgatcagctc cgcttcgacg atgaatctcg aggagttttc aaccttgaac
     4741 ctcgtcaagg aactggtgaa gaggaacccg cttctcctcg gggacctcgc aaagctctcg
     4801 ttcctacttc ggtgatgcgc gcagctgctt gttcaggatg gcaaggcact cgtcctctgc
     4861 ctcttttttc gtaaaaaccg tgatcgtatc accgggccgg atcttcacgt tgccgctcgg
     4921 gatgatcagc tcgcccccgg ctctccggat cgcgatgaac acgaagtcct tgaccttgag
     4981 ctccctgatc tcgtggtcca cgatgggggc acccttctct gccacgacct cgaagatcgt
     5041 cccgcccgga atggatgcga gctgctgcat ctgggggttc tccgcccagt aataaagcct
     5101 ctgggcaacg agttcgtcgg gattctcgga tatcttgacg cccacctcgg aaaagaggtc
     5161 ggaatgttcc ttctggttca cgatcgagac aacagtgggt accttgaacc tctttgcaag
     5221 ccagcaggtc atcaggttta ccgagtcgtc gctcgtcgtc gcaacgaggg cgtccgcccg
     5281 atcaatcccg gcatcctcga ggatggactt gtcggttgcg ttcccggtga cggcaagcac
     5341 atcgtagtgc tccagaatct cgctgcagcg ctgctcgtcg cgatcgatga tcaccacgtt
     5401 attgccatgc tccactgcga gctgggtgag actccgcccg atcccgccga gccccacgat
     5461 gatgatgtac atgcgtacgg gttaccacca tcggcattca aatattttgc gggctgcaca
     5521 tgtagtacgt gatgctctgc ggggtcgatg aagcgggcaa gggcgcggta ctgggacccc
     5581 tcgtcgtggc tgctgtcggg tgcgggaaaa aagaagacct cgcggacctc ggtgtgcggg
     5641 actcaaagga gctctcaccg caacggcgcg aggcactcgc tggcgagatc cgccgctcct
     5701 tcccggttgc agtcctctcg ctctcgccag ccgagatcga cgggcgcggg atcggtctca
     5761 acacactgat tgcacggagc cacgcagccg tcatctcgat gctcgcacca tcagtcgccg
     5821 tggtcgatgc ctgcgacgta aacgcctccc gctacggcgg gatggtgacc gggttcctct
     5881 cggttccctg ccgggtcgtc tcctgccacc atgccgacag gcagcacccg gcagtctccg
     5941 ccgcaagcat cgttgccaag gtggagcggg acagcatgat ccaccgcctc catgacgagt
     6001 ggggatcgtt cgggagcggg tacccgtccg accctgtcac catccggttc ctcgagaggt
     6061 acctcgaaga gaagggggag atcccgccca tcgcgcgtaa aagctgggag acgacgagga
     6121 ctatccttgc ccgggcggaa cagcgtgatc tcctgaaatt tctctaaaac cggtaaatgg
     6181 atacttttac agctggtctt ttccaaacct ctctgccttc cacactttta tgtagatttc
     6241 ccacgtaata taagggaatg cactggctct tctgggtcgt ccttgcactc ctcctctaca
     6301 cggtggcagc cggttacatc tacctccgga aggccgcata cgagagggag aaggccgaca
     6361 ggatcgcgtt tcccgaagaa gggacacgtg aaaagtcagt atgggattcg atcgtcttct
     6421 atggaccggt gcttgccata aagacggacc gggtcgggtt ctttgacagg tacatccggt
     6481 atacaccaat cctccgtgtc tacgcaacgc tcggcgtcgt catggtcgcc ctcatctcgg
     6541 ccggtatcgc tgcaatcctc ttcctctccg tccgtctcac gttccttttc cggccggaac
     6601 cgacgggaat ctacgcaccc cagaacatct tcctgatccc ggggatcaac gagtacgtcc
     6661 cgtccacggt cgcggtctgg tttgcattcg tcctgacgat tgccatccac gagtggggac
     6721 atgggatcct ctgccgcgtg gagaacatta ccgtgcggag catgggggca ctcgtcgccg
     6781 tcatcccgat cgggtttttt gtcgagccgg acgagcagga actcgagaag tcccgtggca
     6841 tgccgaagat ccgcatgttc ggggccggta tcacgaacaa catcgtggtg gggacgatct
     6901 gctttgtcgc actcatcctc ctcttcggca tggtcgtccc gacgggaaac ccggtcatcg
     6961 ccggggtgta caagaactac tcggcatggg acgcgggagt ccccgcaccc tccgtcatca
     7021 cggcggtcaa cggcattccg gttgcgagcc gggacgacgt ctcccgcatc ctgaacgcca
     7081 cgcggcccgg tgaccaggtg accctcactc tcgatgccgg gggggaggtc agggactatg
     7141 cactcgtcct gtccgaatgg ccggaagaac tgggactgca tcactcaggg ttcatgggta
     7201 tttcgtacta cgacggcgct gccatcaagg agggggtccg cgagagcctc tcgttccccg
     7261 gcctcatccg tttcctcacc atacccttcg accccactgc cgcaggccag gcactgcgtg
     7321 tactggcgtt cgagacgccc gaaacccggt tctacgaaga accattcccg ggattctggg
     7381 gactggtcca tgtcctcttc tggtgtgcct ggatcaacat caacgtcgga atattcaacg
     7441 ccatcccgat ggtgccgctg gacgggggat acatcctcaa ggagggagtc gagaggctct
     7501 tcgagcggtg ggggctctcg aaatacgcta ttcccgtcgt ctccctggtc tcctccgtca
     7561 tggtggtgat gctccttgca ctcgtgctcc ttccctacct gctccacatc taggtcattc
     7621 tcccggccga cagcggatcc ttccttcccg gacgaccccc tctgccggga aggaatgcat
     7681 aagtgccatc cttcacacat gtacagcaac ggatcctgca catacgggag tactgtgacg
     7741 caacgatgat cctccgaccc tgcaagaaat tgtacaacaa cgagacccag aggacgactt
     7801 cgcccgagga gactctcgcc cgcgtggaaa aggcgcttcc cgccgcaggt atcacgaggg
     7861 tcgccgacat cacgaacctc gacaggcttg gcatcccggt cttttccagc atccggccaa
     7921 cggccgggag gggtgcgatc tccgtgtaca acgggaaggg ggctaccccg acggaggcac
     7981 gcgtatcggc tatcatggag ggcatcgagc ggtactccgc cgaagtcccg cccggcacca
     8041 ccctcccgct ggcccggtac ccggacgtcg ccggcgatgt ccctgtcctc gaccctgccg
     8101 atctcatcct tccccggggg aaggaccccc ggatgaccat tccctggatt ggcggttacg
     8161 atatccttca ggaagaggag atcctcgttc cggcaagtgc cgtcttccac cccctgccgg
     8221 aaacataccc gcagctcttc aggacatcga caaacggcct tgcgtccgga aacacgctcg
     8281 aggaggcagt gttccatgcc ctcatggagg tcatcgagcg cgatgcgtgg tcactcgtcg
     8341 aggcgagcag ggacacgggc ccccgtgtca cggcaatcgg ggactccctc ccggccagtc
     8401 tcctctcccg gttcgcatcc gcacaggtcg aagtccacgt cagggatatc acgagcgacc
     8461 ttggcatccc cactttcgcc gcggtctccg acgacctgca gctccgcgac ccggccctcc
     8521 tcaccatcgg gatgggcacc cacacgagtg cccggatagc cctcctccgg gccctgacgg
     8581 aagtggccca gagccgcctg acccagatcc acggcgcccg ggaggatacg gatactgccg
     8641 atctcaggcg cagggcggga tacgagaggg tccggaggat gaacgcgtac tggttcgacg
     8701 ggaaatccga ggagccgttt gaccaaatcc cctccttcga taccgacgac ttcctctctg
     8761 atatcaggat cgcgctcgat cggatccgcc gtgccggcat ggagcgggtt atcgtcgttg
     8821 acctgacacg gcccgagata ggggtacccg tcgtcagggt catcgtcccg ggcctcgaag
     8881 tctatgcaat ggacccgcaa agggcagggg gaaggtgccg tgacgcacgg aatcgtcgtt
     8941 tttctcggtc ccagctgtga ccggtccgtt gccggacgga tcgttgccgc ggactaccgt
     9001 ccgcccgctg cccggggcga tatcacctcc gcagctgccg ggggtgcccg catcatcacg
     9061 ctcatcgacg gtgttttctt ccaggagtgt gcggttggtc accgcgagat cgttgccgcc
     9121 ctctcgcagg gcatccgtgt catcggtgcc tcgagcatgg gcgcactccg tgcctcggag
     9181 ctccacacgc tcggaatgga gggtgtcggc ctcatctaca ggctttaccg ggacggcagg
     9241 ctcgtctccg acgacgaggt cgcactcgtc tacgaccccg agacctactg tgccctctcc
     9301 gagccgctca tcaacatccg ctgcacgttg cgggaagcac ggaacgcggg tatcatcacg
     9361 ggaaccgagg aacgggaact cctcgcttct gcccggtcac tgtactttcc cgagaggacg
     9421 tacgcgcttg tctgcaggca tgccggggaa aagatcccag gagagacatg ccagagattc
     9481 cttgagtttg cccggtccca tgcggtggac cagaagagag aggatgcgat cgctgcactc
     9541 aggcggacac gggaagttgc actcgaggcc gggattctga aagaatagca ggggaacagg
     9601 aatgatccgg gtgccggtcg cgcctgcgcc ccgatcaacc atttcacgca gaggcagtcc
     9661 tgttcatgaa cgaggatcgc agcgaattca gctgttcttc ctggtaccgg acgttcattt
     9721 ccatgttgcg gatcgccatg gaaaaatcat cttccccttc ttcttccctt gcctcgctcg
     9781 tgcggtaggt gttttcgagt atcttgagga ggcgcttgtt gatatcgatg ctcctttgca
     9841 ggcgcttgta gttctggatg actgcctcat cgacccctgc ttcccgtgcc atctcgagat
     9901 ccttttcgag taccctcctg cggttcagct gggcctcgat agcctcgtag agctccttgt
     9961 gggtgatggg cttcatgata taatcctcga tgtagatacc gtattcctgc gcctcgttcg
    10021 gggtcagctg cttggcggtg agcatgatga cagggatatc cctgatcctg tggtcattct
    10081 tgatgtgcat cagggtctcc cagccgtcca tgggttccat catgatatcg aggaggatga
    10141 ggtcgggttt cacggtctgg aggaggtcga gtgcctcctg gccgccgtat gcggcaaccg
    10201 tctggtagcc ccccctctgg agcatcgtca cgaagatatc gacgataaag gggctgtcat
    10261 cgatgaccat gatggtgtac atattcagaa agaccccccg atctcgctgg caatgatttc
    10321 tagcatccgg gcgccgggcg agtgctcaaa acccctttcc gccacgacaa cgatcagtat
    10381 cttgtcacct gccccgagca cgacgaggga atgtgcacca ccgtggacgc agacatattc
    10441 aggcggtgcc atcttcagaa tccctgatgc agactcggcc gaggcaaaga gggtggcgca
    10501 catggctgca agccagggct cattgaaatc cctctccagc gactggccaa gcatgattcc
    10561 gtcgcgggag acgagggcac atcccttgac tccgtcgatt gcccgcacct tctcaatgta
    10621 tgcttttacc ttctccttca gcatgtgtta ctcaccgtca gggaccgctt tgccacccct
    10681 tacctgcaag aatgatctat tgtgtattca tcctttttgt tgttattcct gatcaccgga
    10741 cacccgtttt cccattgcac gagccatgag aaccctgtca ggacgtgcgg tataaccgct
    10801 gcgaccggaa ttttcccgat aggtgccttc ccaataaaat ttccgatggg atattttatt
    10861 acgcatccct tccatacatt ttacagccca gaatggtgac attttgggtt ttgaacggca
    10921 atatatcagc ttcccgggct ggaaaatgca cgttcccttc catctgatcc ggggccatag
    10981 ggtagcctgg ccatcctagg agactggggg tcttctgacc tgcg
//
LOCUS       DAOOJU010000043        10634 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5614_length_10634_cov_16.281218, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000043 DAOOJU010000000
VERSION     DAOOJU010000043.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 10634)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10634)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10634
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5614_length_10634_cov_16.281218"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(525..869)
                     /locus_tag="PK679_08515"
     CDS             complement(525..869)
                     /locus_tag="PK679_08515"
                     /inference="COORDINATES: protein motif:HMM:NF024299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC56033.1"
                     /translation="MEQKIPAYQSPDVAYSLRMATEALQSGNYSRALEFIEKTLSIDP
                     DSAMAWHEKANCLDEMGRCEEALNCYETAIRLDSNHAEAWFNKGLTLKKMGREKEAFD
                     CMSRGVDLALGK"
     gene            1141..3789
                     /locus_tag="PK679_08520"
     CDS             1141..3789
                     /locus_tag="PK679_08520"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56034.1"
                     /translation="MNHSQSENLERIKQLLSRHPEGLCINEIAKTLKRHRNSVSRDLH
                     ALLVSGQVHDHAFGTTRVFTLVRRDGRFSILDATHDMVLILDHGGTIVNANISLLGFL
                     EERRESVIGHKVSEFPLLSELISWKSTEEISEEWLRGITSRFHSKDNQSHYDITSRPL
                     LCGDGNEGCMILIHDRSEIENIQGLMDEEKRVLDAITEDLSLLVIRLLPDGRIISGNA
                     QFLSRFCPRPKGAERTEFCSFLAPADAGVLKSSINNLSHQVPVITHIFSMVDPYGQKS
                     LIEWKFHGFFDESLHLCHILAIGSDVTDTIGSRNRTREMEDYMKFLSNAIADFQRVNT
                     SDDIFSRIPLHIGTLIPGSRIVVFEVHQDTGTCSFKGMDRESQAIVDQSSRECASGAA
                     SFSYTIQDAPSVLPKMPGPCNCTWAAPHFSRSFLARLKPGAGIPEWVADANEVCCAGI
                     GENDRLCGIVEIFADRDAVLPREEFVLQYLELLGLIFRQIALLQSEMVSGEQFRTIAL
                     NSPHPISIIDRNGRYIYLNHHFSDLFGYTKDDIPDGKTWFIKAFPDLSEQRHARDLWK
                     GDLFSSPPGTVRPRQFKVRCKNGEFREILFLPVMLSNGDHVVIYQDMTPFLESALRQN
                     LLDDIFRSSQDGIFSVTPDGRILSWNPAAERIYGYPAEEIIGRDVAILEPSSLKGEVH
                     RILRQVMSGEPLIAHETRRVRKDGKVIDVCVTVSPIFNDKQKVVGASTIVRDISQKKA
                     EERLKSAEGQYRESVGDINVGVYRSTGDPEGKFVWGNTSLVGILGFESMDLLKDISVS
                     SLFAETGGRAELLVALKRDGFVKNREIQLRRPDGRIIHVLVTAIATFNPDQTIAYING
                     IVEDVTYTKFLEEQVSRLRERQVSPL"
     gene            complement(3886..4626)
                     /locus_tag="PK679_08525"
     CDS             complement(3886..4626)
                     /locus_tag="PK679_08525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012618715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HPC56035.1"
                     /translation="MPPALKNDLPARRLREREREKEALLKFPVEELVNIIMDVGFSCD
                     LCAKCCTRAFNGHVLLLDDEAARIKDRYPAALEPVPFFDFCDQEGTFYVSGYTIRTVK
                     DKVGSCWFLERGRCTVYEFRPRVCRIYPYMLHREPDESGRVDWRQISGLNQHGEYHRE
                     ISREYANQIARDVIAFEKAVLEHEIAFLEATGSFFARKGLFHVRKMYDNQIKRLAHGI
                     SVPVRVYSHGSFDQWITDGKVTKRQMVE"
     gene            complement(4697..5956)
                     /locus_tag="PK679_08530"
     CDS             complement(4697..5956)
                     /locus_tag="PK679_08530"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: protein motif:HMM:NF002381.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HPC56036.1"
                     /translation="MVRTGVYSEVGRLRAVIVHRPDLSIRRLTPANCRDFLFDDILWV
                     EKAQREHDAFVEVLREEGVAVYYLRDLLAEVLKEEECRQWVVNRVVSPMTVGISACTP
                     VRLCLSGMEPAQLATHLVGGLTRRELECIHLEGMNRSSLQVASTPPDSFILPPLPNTL
                     FPRDSSSWIGNGFTINPMHWPVRRLEAVNMAAIYRFHPLFKTSGARTWYTCVDSTGEN
                     PLPFLAIPSMEGGDIMPIGKGTLLVGMGERTQSPMIERLAGTLLSAGGVEQVIVAQMT
                     PDRAHMHLDTIFSMLDVGMVTVYPKVTETLRTFTIKPGEANRPFRVSEEGDFLSQVGS
                     AMGTERLTVIPTGGDEYDAAREQWDDGNNVLAIRPGLVVAYDRNSHTNRNFEKAGIDV
                     VEIEGSELSRGRGGGHCLTCPISRDGI"
     gene            complement(5966..6895)
                     /gene="arcC"
                     /locus_tag="PK679_08535"
     CDS             complement(5966..6895)
                     /gene="arcC"
                     /locus_tag="PK679_08535"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HPC56037.1"
                     /translation="MRIVIALGGNALLKRGDPMTADIQRENIRSVAGHIAPLAHEHEL
                     IISHGNGPQVGLLALQAACYTRVEPYPLDVLDAQTEGMIGYMIEQELMNHLPHERPCA
                     TLLTMVEVDPGDPAFSNPAKFVGPVYGKEEMERISREKGWIFRMDGDSWRRVVPSPNP
                     CRIVEIMPIRLLIEKGVTVICAGGGGIPVVRVPGTSQRFSGVEAVIDKDLASALLARE
                     VNADLLVMATDVDGVYLDWKTPRARRIEHATPGSLRKIDFAPGSMGPKVEAACRFVEA
                     TGKRAAIGALEDIQELVSGDAGTQVTPGSSAGG"
     gene            7078..7572
                     /locus_tag="PK679_08540"
     CDS             7078..7572
                     /locus_tag="PK679_08540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56038.1"
                     /translation="MAGHGKKGGTTLTENLATGAGEPGYESRCEEDLSCFLRAHPVKI
                     RRLARACGCRCEHCGFSYPINLLSVHILDPQNSPLSSESDPQSLLLVLCPTCLSLFAT
                     PGVSREQKTVLVRLRPDDTSQAMRKILMTRSRPYSPPESRDWAEIFGEIMTGCAPDLC
                     LNGG"
     gene            complement(7586..8251)
                     /locus_tag="PK679_08545"
     CDS             complement(7586..8251)
                     /locus_tag="PK679_08545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="HPC56039.1"
                     /translation="MVVEKSFPVCLVSWRNAVRLSRALAEMIRDSDTPDLVVAIGRGG
                     FVPARIVCDSLMLSTLTSIRVEHWGVAARSLESATIRYPLPIPVRDMDILVVDDVTDT
                     GKTLEVAVRYLREQSPAGIRTAVLHHKTCSAFVPDYHVVVENSWRWIVYPWALHEDLA
                     GFCESVIGGEPVSVDDILSRLKERYDMVPARRDLKGALRNLIIQGRVEPVKKRFLSKR
                     ARE"
     gene            complement(8343..8954)
                     /locus_tag="PK679_08550"
     CDS             complement(8343..8954)
                     /locus_tag="PK679_08550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HPC56040.1"
                     /translation="MKFTRMQLEALKELANIGSAHAATSLSQIIGSSVNMTVPDVSLL
                     DISDLGTVMGDEVATMVVFELQGDLPHGGFLLLHFSRESASKMAAVMCGVSSCDSPMS
                     ELMKSALVEAGNIMVSSFLNASSELLGIMMLPSPPYLVTDILHATVQSLVVGMGVDLD
                     DILVFRIQLTSPEYRIEGNIVLLIEESTLQKVAEILESMVGNP"
     gene            complement(9060..9632)
                     /locus_tag="PK679_08555"
     CDS             complement(9060..9632)
                     /locus_tag="PK679_08555"
                     /inference="COORDINATES: protein motif:HMM:NF015674.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HPC56041.1"
                     /translation="MTEVSTEESLCRMKWSTFVLTGIMSLVFGILFFLFPALTAEVVV
                     TLLGIIIIVLAIFAIVLALLSRVGDTYSGLLLIGGIAGFFAGMAAIISPLLFGAFLTI
                     VLGAVLLVTGVVTIAMGFSEKDRRGRGSMFLLGVVSILFAVLFMFYPVFGSIILFGYM
                     VGIYFVVYGVLLVGTGFIVKKIVPEICSQD"
     gene            9760..10614
                     /locus_tag="PK679_08560"
     CDS             9760..10614
                     /locus_tag="PK679_08560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC56042.1"
                     /translation="MHRIINWNEMWKAIHVASPGRVKKDRDPAAIWDKKAGAYQKVTR
                     GEKIGTEKDLEFIQLRPDDTVLDMGAGTGRLAVPIAGRVAHVTALDASGGMLRILEEN
                     MHKEGHSNYSCIRMKWEDVVIGRDIEPHDVVIAAFSLGFYDLAAALFKLDAAARRAVY
                     LFWHAGEWRGKEEMDLYRAVFGEQGALQKGYPDYIFPVNILHDAGIYANVRVYPAIWE
                     TVHESVDEAVESWVSLHCPDLSDTTPVREFFARVLHREEPGGPLVYRAVRPTAVVWWE
                     KENQHAWS"
BASE COUNT         2476 a         2929 c         2796 g         2433 t
ORIGIN      
        1 cgaggttgaa ggaacacccc gtcccgcaat agggacaggt tgtctgtacg tactttgcat
       61 tcatttaaac acctgtatac ggtgccgtgt attgacccgc ataaaataaa agtatctaaa
      121 cgatattttc aaaaaataaa aattatatta aaaatttgaa ttgtcaatat aatctggtta
      181 acataattaa tgccatgcat ttatgagtgc aaataccgcc tcgcacatcg ttataaaaga
      241 ctcgaaagat gttattcctg ccatgttcag gtgaacatgg tattgtttcc acagtgaccg
      301 tataaaacgg aataaaaaaa aactcactct cttcttttta ataaggtaag aagcccggga
      361 agtcataatc tatcgtgcgg tgctgcatgc cttcagcact gccgcttcct tcgggcaacc
      421 gatggcgcgt tgatgacccc atttgccttt gaatgacgaa accggaccag tctgccggat
      481 aaaaaacgaa tgaatgaaaa gtgtgagata tgaggggaca ggctctactt cccgagggcg
      541 agatcaactc cccggctcat gcagtcgaat gcttcttttt cacgccccat cttcttgaga
      601 gtgagtccct tgttgaacca tgcctctgca tggttggaat cgagtctgat tgcagtctcg
      661 taacagttca gtgcctcctc gcagcgtccc atttcatcca ggcagtttgc cttttcgtgc
      721 catgccatcg cagaatcagg gtcaatcgag agcgtttttt cgatgaactc cagggcacgg
      781 gaataattcc cgctttggag tgcttctgtt gccatccgga gggaatatgc cacatccggg
      841 gactgatagg ctggtatttt ttgttccatt ttttttcctc cctttaccct ggtcttctga
      901 ccaggattga aattatatca aaaggtgcct tttattaacg atttgccaga atgaagagca
      961 ttggagatac gattggcaac ttccccggca cttgtgccat tactactgtc atgcgcaggt
     1021 gttgtgcagt gtttctttgc agaccacggt tatatatact cattcagaaa atgactgact
     1081 agcggtatca attggagaag ggtcagccag gagcccggtt gtccggggag gggggggaaa
     1141 gtgaatcatt cgcagtcgga aaaccttgaa agaataaaac aactgctttc gcgccacccg
     1201 gaggggttgt gtatcaacga gattgcaaaa actctcaagc gccaccggaa ttcagtctcg
     1261 cgggacctcc atgcactcct cgtctcgggg caggttcacg accatgcgtt tggaacaaca
     1321 cgcgttttta ccctcgtccg gagagacggg aggttttcta tccttgacgc cacccatgac
     1381 atggttctta tactcgacca cggagggacc attgtcaatg caaacatatc cctccttggt
     1441 ttcctggagg agagacgcga gagtgtcata ggccacaaag tgagtgaatt ccctcttctt
     1501 tccgaactta tctcctggaa atcaacagag gaaatctccg aagaatggct ccgcggaatt
     1561 acgtcccgct ttcacagtaa agacaatcaa tcccattacg atatcacgtc aagacccctt
     1621 ctctgcgggg atgggaatga agggtgcatg atccttattc atgatcgttc ggaaatcgaa
     1681 aacattcaag ggctgatgga tgaagaaaaa agggttcttg acgcaatcac ggaagatctc
     1741 tccctccttg tcatccggtt actccccgat ggccgtatta tttcagggaa cgcccagttt
     1801 ctttcacggt tctgccctcg ccccaaggga gcagaaagga cagagttctg ttcctttctg
     1861 gctcctgcgg atgccggggt cctgaaatcc tccatcaata acctttctca ccaggtgccg
     1921 gtaatcacgc acatcttctc catggttgac ccgtatggcc aaaagtctct gattgaatgg
     1981 aaatttcatg gttttttcga cgagagcctg catctttgtc atatcctggc catcgggtcc
     2041 gatgtcacgg ataccattgg gtcaaggaac cgcacacggg aaatggagga ctatatgaaa
     2101 ttcctttcaa acgcaattgc tgatttccag agggttaata ccagtgacga tatcttttcc
     2161 cgcattcccc tccatatcgg caccctgatt cccggatccc gtatcgttgt tttcgaggtt
     2221 catcaggaca cgggaacatg tagttttaag ggcatggaca gggaatccca ggcgatagtt
     2281 gatcaatcca gcagggaatg tgcttccggg gcagcgtcgt tttcctatac tatccaggat
     2341 gcgccttcag tcctcccaaa gatgcccgga ccgtgcaatt gcacctgggc cgctccccac
     2401 ttctccaggt cattccttgc ccgcctgaaa cccggtgcag gcatcccgga atgggtggcg
     2461 gatgccaacg aagtttgctg tgctggaatc ggtgaaaacg acaggctctg cggaattgtc
     2521 gagatatttg ctgatcgcga tgctgtcctg ccacgcgaag aattcgttct gcaatacctg
     2581 gaactccttg gattaatatt ccggcagatc gcgctcctcc agtccgagat ggtgtccggg
     2641 gaacagttcc ggaccattgc cctcaactca ccgcatccca tctccatcat cgatcggaat
     2701 ggcaggtata tctacctcaa ccaccatttt tccgatctct tcgggtacac gaaagatgat
     2761 atcccggacg ggaagacgtg gttcatcaag gcattcccgg atctttcaga gcagaggcat
     2821 gccagggatt tgtggaaggg agatctcttc tcctctcctc ccgggacagt ccgtccacgc
     2881 cagttcaagg tccggtgcaa gaacggggaa ttccgggaga ttcttttcct gccggttatg
     2941 ctgtccaacg gagaccacgt cgtcatatac caggacatga ccccgtttct tgagagtgcc
     3001 ttgaggcaga atcttctcga tgatatcttc aggtcttctc aggacgggat attcagcgtg
     3061 acacccgatg gacgtatcct ttcctggaac ccggctgcgg aacggattta cggctaccct
     3121 gcagaagaga taatcgggag ggatgttgcc attctcgagc cttcgtccct caaaggagag
     3181 gtccacagga ttctcaggca ggtgatgtcc ggagaacctc tgattgccca tgagacccgg
     3241 cgggtcagaa aagacggtaa agtgatcgat gtctgtgtga cggtatcccc catcttcaac
     3301 gataaacaga aagttgtcgg tgcatcgaca attgtcaggg atatttccca aaagaaggct
     3361 gaagagaggc tcaagagcgc ggaaggccag taccgggaaa gtgtcgggga tatcaatgtc
     3421 ggggtttacc gatcaaccgg tgaccccgaa ggaaaattcg tctggggtaa tacctctctt
     3481 gttgggatac tcggttttga gtccatggac cttctgaaag acatctctgt cagctctctt
     3541 tttgcagaga ccggggggag ggcagaactc ctggttgcgc taaagagaga cggtttcgta
     3601 aagaaccgtg agatccagct ccgcaggcct gacggcagga tcatccatgt actggtaacg
     3661 gcaattgcca cgttcaaccc tgaccagacg attgcttata tcaacggcat tgtcgaagat
     3721 gtcacgtata caaaatttct ggaagaacag gtttccaggc ttcgggaaag gcaggtatca
     3781 cctctctgac ccgtacccgt tttcccgaac aatgcatcat tccctgtaat cttcccacgg
     3841 gagagatctc cttcgaagag aacgatcatg ttcgtggaaa aaaaatcatt cgaccatctg
     3901 gcgctttgtc actttcccat cggttatcca ttgatcgaat gacccgtggg aatagaccct
     3961 gacgggaacg gaaatcccgt gcgcaaggcg cttgatctgg ttgtcgtaca tctttctcac
     4021 atggaaaaga cctttcctgg caaaaaatga tcctgtagct tcaaggaacg ctatctcgtg
     4081 ttcaagaacc gccttttcaa atgcaatcac gtcccgtgcg atctgattcg cgtattcgcg
     4141 tgatatttcc cgatggtact caccatgctg gttgagcccg ctaatctgcc tccagtccac
     4201 cctgccggat tcgtctggtt cccgatggag catatacgga taaatcctgc acacgcgggg
     4261 ccggaattcg tataccgtgc atcttccccg ttcaaggaac cagcatgaac cgaccttgtc
     4321 cttcacggtg cggatggtat aaccggacac gtagaatgtt ccttcctgat cgcagaagtc
     4381 aaaaaacgga accggttcga gtgcggcagg gtatcgatct ttgatccgtg cagcttcgtc
     4441 atcgaggaga agcacgtgac cattgaatgc cctcgtgcag cacttcgcac acaggtcgca
     4501 tgagaacccc acgtccatga ttatattgac gagttcttcc accgggaact tcaggagggc
     4561 ttctttttcc ctttccctct cccggagacg ccttgcgggg agatcgtttt tcagggctgg
     4621 gggcattgca ggagttacaa ttgtattctc ccgaggggaa aaatgtgatt gatgggttct
     4681 atcctccgct gtcggttcat atcccgtccc ggctgatggg gcaggtcagg cagtgaccac
     4741 ccccccggcc ccgggagagc tcggatccct cgatctccac cacgtcaatt cctgccttct
     4801 cgaaattcct gttcgtatga gagttcctgt cgtatgcgac cacgagaccg ggtcggatgg
     4861 caaggacgtt gttcccgtcg tcccactgct cacgggccgc atcgtattca tccccccctg
     4921 tcgggatcac ggtgagcctc tctgttccca tcgcagagcc cacctgggag aggaagtctc
     4981 cttcctctga cacccggaac ggtctgttcg cctcgccggg tttaatggtg aaggtccgca
     5041 gcgtttccgt caccttcggg taaacggtga ccatcccgac gtcaagcatg gaaaagatgg
     5101 tgtcgaggtg catatgggca cgatcggggg tcatctgggc cacgatgacc tgttccaccc
     5161 cgcctgctga gagaagtgtg cctgccagcc gctcgatcat cgggctctgg gtccgctcac
     5221 ccatcccgac gaggagggtt cccttcccaa tcggcatgat gtcgccgcct tccatcgatg
     5281 gaatagccaa aaaaggaagc gggttctccc ctgtactatc gacgcatgtg taccatgtcc
     5341 gtgcgccgct ggtcttgaag aggggatgga accggtagat tgccgccata ttgaccgcct
     5401 cgagccttcg gacaggccag tgcatggggt tgatcgtaaa accgtttccg atccacgatg
     5461 atgagtcgcg ggggaagaga gtgttcggga gcggcgggag gatgaaagaa tcgggcggtg
     5521 tcgaggcgac ctgcagggac gacctgttca ttccctccag gtgaatgcac tcgagttccc
     5581 gccgcgtcag gcccccgacg aggtgcgtgg caagctgcgc gggttccatc cccgacaggc
     5641 ataaccggac cggcgtacat gcagatatcc cgactgtcat cgggctgaca accctgttca
     5701 caacccattg acggcactcc tcctctttga ggacttctgc cagaagatcc cgcaggtagt
     5761 aaaccgccac cccttcctcc cggaggacct caacgaatgc atcatgctct ctctgggcct
     5821 tctcgaccca gaggatatcg tcaaagagga agtcacggca gttcgcggga gtgaggcgcc
     5881 tgatactcaa atccggacgg tgcacgatta cggcacgaag cctgccaacc tcggaatata
     5941 ctccggttct taccacggtg ttctgtcacc cccctgcact gctgccgggc gtaacctgcg
     6001 tcccggcatc tccgctgacg agctcctgta tatcctccag tgcaccgatt gcagccctct
     6061 ttcccgtggc ctccacaaaa cggcaggccg cttccacctt cggacccatg gatcccggcg
     6121 caaagtcaat cttccgcagg ctgcccggtg ttgcgtgttc gatccgccgg gcccgggggg
     6181 tcttccagtc gagatagacg ccgtcgacat cggtagccat gacgaggagg tcggcattga
     6241 cttcccgggc aagcagggca ctggcaaggt ccttgtcgat gactgcctcg actccggaaa
     6301 acctctgtga ggttccgggc acccggacaa ccgggatacc tcctcctcct gcacagatga
     6361 cagtcactcc cttttcaatg agaaggcgga ttggcatgat ctcaacgatc ctgcatgggt
     6421 tgggggatgg aacgacccgc ctccatgagt ccccgtccat ccgaaatatc catccctttt
     6481 cccgggatat tctctccatt tcttcttttc cgtataccgg tcccacgaat ttcgcagggt
     6541 tcgaaaaagc cggatctccg gggtctacct cgaccatcgt gagaagagtc gcacacgggc
     6601 gttcatgcgg caggtggttc ataagctcct gctcaatcat gtaaccaatc atcccctccg
     6661 tctgggcatc caggacatcg aggggatagg gctctacacg ggtatagcat gcagcctgga
     6721 gggcaaggag tcccacctgg ggaccattcc catgggagat gatgagttcg tgctcgtgtg
     6781 caaggggtgc aatatggcct gcaaccgacc ggatattctc cctctggatg tctgccgtca
     6841 tgggatctcc ccttttcagg agagcgtttc ccccgagtgc gatcacgatg cgcatgtata
     6901 ttcactgctg tctccaggac tcccggacag accactcttt gtcccgtccg gtattatccc
     6961 ttgccccttt ccagacagtt ttcctggtct ctccgaacca gatggattgg agcaaacgta
     7021 tatgggagcc ggttcccata caccgcacaa ggtgcatttt tcagggagga acccgggatg
     7081 gcaggacacg gcaaaaaagg tggaacgacc ctgacagaaa atctggcaac aggtgcaggc
     7141 gaaccgggat atgaaagccg gtgcgaagaa gacttatcct gctttctccg ggcacacccg
     7201 gtcaaaataa ggagacttgc gcgtgcctgc ggatgccgct gcgagcactg cgggttttct
     7261 tatcccatta acctcctctc tgtccacatc ctggatccgc agaatagtcc actatcctct
     7321 gaatccgacc cacagagctt actcctcgtt ctctgcccga catgcctgtc gctctttgca
     7381 accccgggcg tgagccggga gcagaagaca gtcctggttc gtctccggcc ggacgatact
     7441 tcgcaggcga tgcgaaaaat cctgatgacg aggtcccgac cctactctcc cccggagtca
     7501 cgcgactggg cagagatatt cggggagatc atgaccggtt gtgcccccga cctctgcctt
     7561 aacggcggat aacacccgga cagccctact cccgtgctct tttcgacagg aacctttttt
     7621 tgaccggttc aaccctgccc tgaatgatga ggttacgcag ggctcccttc agatcccggc
     7681 gggccggcac catgtcatac ctctccttca gcctggaaag gatatcgtcc acggataccg
     7741 gctctcctcc tatcacggac tcacagaatc ctgccagatc ttcgtggaga gcccagggat
     7801 agactatcca tctccaggag ttttccacaa cgacgtggta atcggggacg aacgctgaac
     7861 atgtcttgtg atggaggact gctgtcctga tgcccgccgg ggactgctcc cgaaggtatc
     7921 ggacagccac ttcgagcgtt tttcccgtat cggtcacgtc atccacgacg agaatgtcca
     7981 tatcccggac cggaatcggg aggggatacc ggatggttgc agactccagg ctccgggctg
     8041 ccacacccca gtgttcaacg cgtatcgaag tgagcgtgga taacatcagg gaatcacaga
     8101 caatccgtgc cgggacaaaa cctccccttc cgatggcaac aacgaggtca ggggtatcgg
     8161 aatcccgtat catttcggcg agagcacggg agagcctgac agcatttcgc cacgatacga
     8221 gacagacggg aaatgacttt tcaacgacca tgggatgaac acctgtcaaa tccctgaaat
     8281 gaacagcctt tcggtcgggc ttgcatccat gtgtcttccg ggaaccgttt cacaagcaac
     8341 aattatggat ttccaaccat ggattcgaga atttctgcca ccttctgcag ggtgctctcc
     8401 tcgatgagga ggacgatatt tccctctatc cggtattccg gcgaggtcag ctggatacga
     8461 aatacgagaa tatcatcgag atcgaccccc atccccacga ccagcgactg gactgtcgca
     8521 tgcaggatat cggtgacgag gtaaggcggc gaggggagca tcatgatacc cagcagttcg
     8581 gaagaggcgt tcagaaacga tgagaccatg atatttccag cctcgaccag tgcgctcttc
     8641 atgagctcac tcatgggaga gtcgcatgag gaaacgccac acatgaccgc tgccatcttc
     8701 gatgcagatt cccgggaaaa gtgcaggagg agaaagcccc catggggaag gtctccctgg
     8761 agctcaaaga cgaccatcgt ggctacttca tcgcccatca cggttcccag atctgatata
     8821 tcgaggaggc tgacatcggg gacggtcata ttgacactgc tcccgatgat ctgcgagagc
     8881 gaggttgccg catgggctga tccgatattg gcaagctctt tcaaggcttc cagttgcatc
     8941 cgggtgaact tcatgcgtac ctgtccgggg tggaagtggc cctttatgaa gattcaccca
     9001 accgggataa aaaatgcacg gttccgggaa aaatccgatt ctccccaaaa aattggattt
     9061 taatcctgcg aacagatttc ggggacaatt ttctttacaa tgaaccctgt tcccaccagg
     9121 agaaccccat acaccacaaa atagatcccg accatgtacc caaagagtat tatggaccca
     9181 aagacgggat agaacatgaa aaggacggca aaaaggatgg agaccacccc gaggaggaac
     9241 atgctcccgc ggccacggcg gtccttctcg gagaatccca tggcaatagt gacgaccccg
     9301 gtcacaagca gtactgcacc gaggacaatc gtcaggaatg ccccgaaaag gagaggggat
     9361 ataattgcgg ccattccggc gaagaagccg gctatccctc cgatgagaag aagtcccgaa
     9421 taggtgtccc ccacccggct caggagggca aggacgatgg caaaaatcgc aaggacgatg
     9481 atgataattc caagcagcgt tacaacgacc tctgcagtca gtgcaggaaa gaggaaaaac
     9541 aggattccaa agaccagtga catgatcccg gtcaggacaa acgtggacca cttcatcctg
     9601 catagtgatt cttcggtaga gacttccgtc atggaaaagt gacctccctt ttctcttttt
     9661 ggcgcgatac gataattcta tgccggcacc ggcgatgtcc ttctctttca tctttcgccc
     9721 ccccctgtta aatataccag ctggaggaga atacaatgca tgcaccggat catcaactgg
     9781 aacgagatgt ggaaggcaat ccatgtcgca tctccgggtc gggtgaaaaa agaccgcgat
     9841 cctgccgcaa tatgggataa gaaagcagga gcgtaccaga aagtcacgag gggagagaag
     9901 atagggacag agaaggacct tgagttcatc cagctccgtc ctgacgatac cgtcctcgac
     9961 atgggtgccg ggacggggag gcttgccgtt ccgatagccg ggcgcgttgc acacgtgact
    10021 gcccttgatg catcgggggg catgctccga atcctcgagg agaacatgca caaggaggga
    10081 cactcgaact attcctgcat ccggatgaag tgggaagacg tcgtcatcgg gagagacata
    10141 gagccccacg atgtcgtgat cgctgcattt tcccttggtt tctatgacct tgcagctgcc
    10201 cttttcaaac tggacgccgc tgcacgccgg gctgtctacc tcttctggca cgccggtgag
    10261 tggcggggga aagaggagat ggatctctac cgggccgttt ttggtgagca gggtgccctg
    10321 cagaaaggat acccggacta catcttcccg gtcaacatcc tgcacgatgc cgggatctat
    10381 gccaatgtca gggtctatcc tgcgatatgg gaaaccgtgc atgaatccgt ggacgaagcc
    10441 gtggagagct gggtttcgct gcactgtccg gacctgtctg atacgacacc ggtgagagaa
    10501 ttcttcgcga gggtgctgca cagggaagaa ccgggtggtc cgctggtcta cagggccgtc
    10561 aggccgactg ctgtggtttg gtgggagaaa gagaaccaac acgcctggtc atagtattct
    10621 tccatccact attc
//
LOCUS       DAOOJU010000044        10477 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_5709_length_10477_cov_14.487814, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000044 DAOOJU010000000
VERSION     DAOOJU010000044.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 10477)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 10477)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10477
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5709_length_10477_cov_14.487814"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            123..470
                     /locus_tag="PK679_08565"
     CDS             123..470
                     /locus_tag="PK679_08565"
                     /inference="COORDINATES: protein motif:HMM:NF013052.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SET domain-containing protein-lysine
                     N-methyltransferase"
                     /protein_id="HPC56043.1"
                     /translation="MEGIPREVWDHLFNVDICDSIIAREPAVRTNHSCDPNAGIVRDV
                     FLVAMRDIKKDEEVTFDYPVVTVDDWQMECRCGSPHCRKIIGNYAGLPDEIKKKYENY
                     TPDWIKGARSGTR"
     gene            536..811
                     /locus_tag="PK679_08570"
     CDS             536..811
                     /locus_tag="PK679_08570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56044.1"
                     /translation="MYLLFFLSSRAGTRDTQPADSNALLLLLLRKGAVTGSGIELRLA
                     GFTGGVILPTGISGKAGEERACEPECREQDAMMTQMRENADGVYGLK"
     gene            complement(865..2571)
                     /locus_tag="PK679_08575"
     CDS             complement(865..2571)
                     /locus_tag="PK679_08575"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HPC56045.1"
                     /translation="MAVSAGWKIFFGIIAIGLCILAAYSIFFAVPHDRVVIVMNGTIY
                     TDPDHPVQNLLIRNGIVQATNVNPAAYRGAEILDLHGFVAYPGFHDSHVHLLEAGYGF
                     SSNCSLYGATDAKSIAAIVGPIAASLPPGEPMIGGGFSLDDYDAWSLADLAQIDAVTG
                     DHPVFLGDQLGHNAIVNTAALKVCNITGTTQPPPGGIIILENGKPTGMLRESAMVPAG
                     NVLFGTFPDAVIGPVTERYLHYWASFGYTSINDLMGSSAGRMFNPELFKKMEREGNLP
                     LRVHYFYTLSSLDEIDDALPYRGNDTDMVRFAGLKIFVDGAFAGGQANTSWKNAKGNY
                     GLTYVYTDDSHGESYNINRIVAKADNLGLNVHYHVQGDQAINAVLTALENQSARNGGL
                     KSNHTLIHLAYVTDEQIARMKKLRNHVSLTVQPAFWDIQENLSRYYGDHTSEAYPFKK
                     LFSSGIPIGISTDFYVSPLSLSPPTAIAGIASQGGNDPRNHTPLTIQQVIRGLTTGSA
                     ATTPSRDIGKLEPGYKADIVIFDQDPNAVPPGQFTRNNPKVLATYINGINVYRADGWA
                     GP"
     gene            3046..4554
                     /locus_tag="PK679_08580"
     CDS             3046..4554
                     /locus_tag="PK679_08580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HPC56046.1"
                     /translation="MKRLLPVTALVILAAFMLAAGCTSVERTTPAASKGDTLLAQAEA
                     RFAEGNFHAAEKLYAGAYAEYKAAGDAAGAKKALNRASTAARMTIEFPYNRPEITALI
                     DEAFPDLSADRKAGFLPCNRSQCITSDGEVWYFSNTIQNIRSHNIDLMREATAKMGET
                     PFFDQLKPVALAPAVEGAENYQNPVAWKGTEVLSIPAKDLPKTGTLRLWIPLPIETES
                     QRNVTIEAVEPARYVRSMTGTGADIGLAYLEIPLHEVTGDSLTVTARFGYTQYEQRFA
                     IDPAKVGTYDTKDPEYTKYTASGKNIVVTPAMKAKALGIVGNETNPYLQADKLYWHVV
                     SHPYSNVPHVRLNVAGTPESVYMLETGFGDCGTQSMYFAALCRSLGIPARAIGGYQLV
                     PGHEGTHFWSEYYLPGYGWIPNDVTIAEGAEWSPNATDDERHQYKAYYASNLDPYRYI
                     IQKDVDIPIVPDPGDAVMFDMVVQSPKAVCDTCDTDPEFALLDNWKVTVQRA"
     gene            4676..9574
                     /locus_tag="PK679_08585"
     CDS             4676..9574
                     /locus_tag="PK679_08585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="HPC56047.1"
                     /translation="MNHQCIMAVLVVLVLCAAAGAAPGEQPWKFHSDLANSGVYDDGG
                     IRPDGTLLWTYMTGGKVRSCPAVVDGVVYVGSRDHTLSALSADTGALLWNVTVGGGIE
                     SGPAVAGGLVYTGSADGSVYAFNASDGSQAWTCTTGGAVRSGPAVAGGLVYTGSNDGK
                     VYALDAETGEPAWQFAAGDPQIASSAAVAGGAVYIGGSSGNVYALDALSGALLWNYTT
                     SGPVQSSPAVVDGVVYVGSDDGTVYALSAPDGALLWNFTTGGAVRSGPAVAGGVVYVG
                     SDDGRLYALDAHTGNPVWSYQAGSGISASPAVAGGVVYAGTSGSPGTFFALDASTGDL
                     LWDHSFGKHPCSGSPAVAHGIVYAGCDDGGLYAFGSSGESPPAGVTGLHAAAATNDSI
                     TWAWTDPATGGFASVRVFLDGEFREDVPAGTGTWTATGLLPETPHTIGTRTVSASGRV
                     NATWVNHTAWTAPEAGQKAWKFRSDPGNTGAYDDGGTRPGNSLIWKSPIENYYGSLPA
                     VVDGVVYVNGIYEMNALDALTGKLLWSSPHGGGMSSPAVVDGVVYTGSSDRTICALNA
                     TTGALLWQYTTEKTVYSSPAVAGGIVYTGGTDEKLYALDAGTGALLWTFDAGAEIRSS
                     PAVARGAVYITGRDGTLSALNATTGALLWSFATGADLVSSSPVVFGNTACFRAAEGNL
                     YALDATTGDLLWTAPASPAEESGPAVAGGMVYTGDGNGTVSALDAADGSPIWTYTAGA
                     PVRHGPSVANGIVYAGSTDGTIHALDAATGDLLWTWATAEGGYTSPVVAGGVLYTTGS
                     GGTLYALATLPDGPPPCVADLHPVTVNGAEITWAWTDPRAIGFSHVRIFLNGVFQENV
                     TAGTGTWTARGLSPSTAYTIGVQTVDTAGRVNQTVVTSTATTGPLSVTHLDPSGAVEG
                     SPSFVLHVYGTGFSPSSVVSFDGVELVTHFENATHISVSVPPGFVGRPRRASITVTDP
                     ATGQASQTVVFPVTDNPTARAREFRSDPANTGIYDDGGRRPVPSLLWMCQTGARVTSS
                     PSVAGGIVYIGSQDRNLYALNATTGEILWKYDTMERNDIVSSSPAVANGVVYIGGLKT
                     KVHAVDAYSGDLLWKYKVPIRTTSRSGISSSPTVTGGTIFIANMDGVVYAFDEETGTL
                     LWNYTVPQATGGERGIYASPAVADGAVYVLTYDGDLYVLDASTGTLLWSYETAGDYGA
                     YASPAVSGGVVYTGSGLNGPFRALDARTGALLWEAPSVVSAYSSPAVAHGVVYTGSMD
                     NSIYALDASDGTILWNFTTGDKVYSSPAVAHGVVYAGSNDCNLYALDASDGRLLWNFT
                     VNDGIISSPAVAGGIVYFGCNDGRVYALGTLPVEPPFADYSANITDGKAPLDVLFTDT
                     SIGIVTWRFWDFGDGTTAWANGTQSVVHTYAFPGNFLVSLTAGNDGGQDTRKKTPLIH
                     VTPSGQRPVAWFTALPMVGYRPLQVRFTDRSMGSPVVWRWDFGDGNSSAEKNPVHTYT
                     AAGTFRVSLTVLSAGGRSSSSSTVWVRERAPIPTITPAPTFSPHPTISPGPTIPPRPG
                     APPVAFFKMSPIMGSAPLAVAFTDLSFNAPTSWSWDFGDGTQSAERNPVHTFTEKGVY
                     TVTLSVENAYGNSSTYRNVYVR"
     gene            9644..10045
                     /locus_tag="PK679_08590"
     CDS             9644..10045
                     /locus_tag="PK679_08590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011448523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="secondary thiamine-phosphate synthase enzyme
                     YjbQ"
                     /protein_id="HPC56048.1"
                     /translation="MMWTRIDVPTGTRTQFIDITGTVAAELEKARVQSGTCTVYVPHT
                     TAGVTINENADPDVARDILSGLARLVPATGDYRHAEGNSDAHIKASLVGSSVTVPVIG
                     GRLALGTWQAIYFCEFDGPRNRHVLVGISGG"
BASE COUNT         2084 a         3275 c         3191 g         1927 t
ORIGIN      
        1 aaaagatctc gtgtatgtga aggaaaagcc gggcatgggg cttgggatat tcgctgtgag
       61 ggatatttaa aaaggacgac atcatcactg ggttttgcgg cccgggagtc cggatcgaga
      121 atatggaggg cattccccgt gaagtctggg atcacctctt caatgtggat atctgcgatt
      181 ccatcatcgc acgggagccc gctgtcagaa cgaaccattc ctgcgatccc aatgccggga
      241 tcgtcaggga cgtgttcctg gttgcaatgc gggacataaa gaaagatgag gaggtcacgt
      301 tcgactatcc ggtcgtcact gtcgatgact ggcagatgga atgcaggtgc ggttccccgc
      361 actgccgcaa aatcatcgga aattacgcgg gcctgcccga tgagatcaag aaaaagtacg
      421 agaactatac gccggactgg atcaaaggtg cacggagcgg aacgcgataa agggatgcgg
      481 ggggccggat ccggtccaca ccgttcctga acgggcctcc gttttcagcg ggcacttgta
      541 cctgcttttt ttcctttcct cccgtgcggg cacacgtgac acacagcccg cagacagcaa
      601 cgccctgctt cttctcctgc tccggaaagg agcggtcaca gggagcggca ttgaactgcg
      661 cctcgcgggg ttcaccgggg gcgtcatcct gccaacagga atctccggaa aagcaggtga
      721 ggagagagca tgcgaaccgg agtgcaggga gcaggatgcg atgatgacac agatgaggga
      781 aaatgcggat ggggtgtatg gactgaagtg aactcagtga gtcagaaaca agcggtgttg
      841 aaaaaaaaat cagggaaatc ctcttcaagg tcctgcccag ccgtccgcac gataaacgtt
      901 tattccattg atatacgttg ccagcacctt cgggttgttt ctggtgaact gccccggggg
      961 aaccgcgttt ggatcctgat caaaaatgac aatatcagct ttatatccgg gctcaagttt
     1021 tccgatatcc cggctcggcg tcgttgcagc actgcctgtg gtaagacccc ggataacctg
     1081 ctgtattgtc aggggcgtgt ggttccgggg atcgttgcca ccctgtgatg caatgccggc
     1141 gattgcagtc gggggtgaga gacttaaggg ggatacgtaa aaatccgtgc tgataccgat
     1201 tggaatcccg ctgctgaaca gttttttgaa agggtatgcc tcagacgtat gatctccata
     1261 ataccgggac aggttctcct gtatatccca gaatgcaggc tggaccgtca gggatacatg
     1321 attcctgagt tttttcatcc gggcgatctg ctcatcggtc acgtatgcga gatgaataag
     1381 cgtatgattg cttttcagac ccccgttcct cgcagactgg ttctccagag cggtcagcac
     1441 agcgttaatt gcctgatccc cctgcacatg atagtggacg ttcagaccga gattatcggc
     1501 ctttgcaacg atccggttga tattatagga ttccccgtgc gaatcatcgg tgtagacata
     1561 cgtgaggcca tagtttccct ttgcattctt ccagctggta tttgcctggc ctccggcaaa
     1621 tgctccgtca acaaagatct tcagacctgc gaaccggacc atatcggtat cattgcctct
     1681 atagggaagg gcatcgtcga tctcatcaag ggacgatagt gtgtagaagt agtggaccct
     1741 caggggaaga tttccttccc gctccatttt tttaaagagc tccggattga acattcgtcc
     1801 ggccgaagac cccatgagat cattgatgga ggtatacccg aatgatgccc agtaatgtaa
     1861 gtatcgttct gtaacaggtc cgattacggc gtcagggaat gtaccaaaca ggacatttcc
     1921 tgcaggtacc atcgccgatt cacggagcat tccagtcggt ttgccgtttt caagaatgat
     1981 aatgcccccg ggagggggct gcgtagtacc tgtaatattg catactttga gcgctgcggt
     2041 attcacaatt gcattatgtc cgagttgatc gccgagaaag accggatgat caccagtgac
     2101 agcatcaatc tgggcaagat cagcaagcga ccatgcatca taatcatcga gggagaaccc
     2161 gcccccgatc atcggttccc cggggggcag ggacgcagcg atgggtccga caatcgctgc
     2221 aatggatttg gcatctgttg cgccgtaaag gctgcagtta ctgctgaatc cgtaaccggc
     2281 ttccagcaga tggacatggc tgtcatggaa acccggatac gccacgaatc catggagatc
     2341 aagaatctct gcaccacggt acgcggccgg gttgacattg gttgcctgaa ctatcccgtt
     2401 cctgataagc aggttctgta ccgggtggtc aggatctgtg tagatagtac cgttcatgac
     2461 gatgacaacg cgatcgtggg gcacagcgaa aaatatacta taagcagcca ggatgcagag
     2521 tccgattgct ataataccaa aaaaaatctt ccatccggca gaaacagcca tcaatatctc
     2581 ctcatgggac taccctctca aaccggtcgg gataccggca acagggagtt atgtgataca
     2641 gggaatgtac ggatgaatga ttaagtatat tgtcattgcg cacggggtat cgacggtttt
     2701 tcggatgatg gtcgtcatgt tcctgacaag gggtggattg ttgatgcggg acctgcgggg
     2761 gtcggtgcac cgggatggcg ggttcagccg gcatggactg ttcccgcttg cctgatcatc
     2821 ggggcaattc ccgtgaatcc ggatacggca ttgttgcccc tgtaatcctg gcgggcacat
     2881 gatgcatcgt gcgcacaaac gcgtccattc ccccgccatc tgctgaaaaa agcctcaccg
     2941 gcaggtgctg cccgggtcgt gctccggaga agggaataga aacccacctt ttaatatgca
     3001 gtcccgcatc ctgaatactt acaatcattt ctcttgcgtg atcccatgaa acgactcctg
     3061 cccgtcacgg ccctcgttat cctcgctgcc ttcatgcttg cagccggctg cacatccgtc
     3121 gagagaacaa ctcccgctgc ctcgaaaggc gataccctcc ttgcacaggc ggaagcccgg
     3181 tttgcagaag gcaacttcca tgccgccgaa aagctgtatg ccggagcgta cgcggagtac
     3241 aaggccgcgg gggacgctgc aggcgcaaaa aaagccctga acagggcctc gacagccgcc
     3301 cggatgacca tcgagttccc ctacaaccgc ccggagatca cggccctcat cgatgaggct
     3361 ttccccgacc tctctgccga ccgaaaagcc ggtttcctcc cctgcaacag gagccagtgc
     3421 atcacgagtg acggggaagt ctggtacttc tcgaatacca tccaaaatat caggtcccat
     3481 aacatcgacc tgatgcggga ggcaaccgcg aaaatgggcg agacgccgtt tttcgaccag
     3541 ttgaagccgg ttgcccttgc cccggcggtc gaaggagcgg aaaattacca gaaccccgtg
     3601 gcatggaagg ggacagaagt cctgagcatt cctgcaaaag acctgccgaa gacaggcacc
     3661 ctccgcctct ggatccccct gcccatcgag acggaatcgc agagaaacgt gacgatagag
     3721 gctgtcgaac cggcacggta cgtcaggtca atgaccggaa caggcgctga catcggcctt
     3781 gcatacctcg agatcccgct ccacgaggtg accggtgatt ccctcaccgt caccgcacgg
     3841 tttggctata cccagtacga gcagcggttt gccatcgacc cggcaaaggt cggcacttac
     3901 gacacgaaag atcccgaata cacaaaatac acggcgtccg ggaaaaacat cgtggtcacg
     3961 ccggcgatga aggcaaaggc gctcgggatc gtcgggaacg agaccaaccc gtacctgcag
     4021 gcggacaagc tctactggca tgtcgtttcc catccgtaca gcaacgtccc ccacgtgagg
     4081 ctcaacgtgg caggcacgcc cgaatccgtt tacatgctcg aaaccgggtt cggggactgc
     4141 ggcacgcaga gcatgtactt cgccgcactc tgccgctcgc tcggcatccc ggcacgggct
     4201 atcgggggct accagctcgt cccgggccac gagggcaccc atttctggtc agagtactac
     4261 ctcccgggct acggctggat ccccaacgac gtcacgattg ccgagggcgc cgaatggtcc
     4321 cctaatgcaa cggacgacga gcggcaccag tacaaggcat actacgcaag caacctcgac
     4381 ccgtaccgct acatcatcca gaaggatgtc gatatcccga tcgttcccga cccgggcgat
     4441 gccgtgatgt tcgacatggt cgtccagtcg ccgaaagccg tctgcgacac ctgcgatacc
     4501 gacccggagt tcgcgctgct cgacaactgg aaagtgaccg tccaaagagc ctgagggaaa
     4561 agggctccct ctttttctcc gggggattcc tgcccgtcct ctcccccgaa tcctggataa
     4621 ctaataaata gtctccttcc agtcttttac ataccacaat caggtcggga caatcgtgaa
     4681 tcatcagtgc atcatggcag tactcgttgt gctcgttctc tgtgcggcag ccggtgcggc
     4741 tcccggggaa cagccctgga agttccactc ggacctcgcg aactcgggcg tctacgacga
     4801 cgggggcatc cgcccggacg gaacactcct ctggacgtac atgaccggcg ggaaggtgcg
     4861 ttcctgcccg gcagtcgtgg acggtgtcgt gtacgtcggg agccgcgacc ataccctctc
     4921 cgcactctct gccgataccg gagccctcct ctggaacgtg accgtgggag ggggcattga
     4981 atcgggcccg gcagtcgcgg gcgggctcgt ctacaccggg tccgcggacg gctccgttta
     5041 tgcgttcaac gcgtccgacg ggtcgcaggc ctggacctgc acgacgggcg gtgccgtgcg
     5101 gtcgggcccc gcggtcgcag gcggcctcgt gtacaccggg agcaacgacg gcaaggtcta
     5161 cgccctcgac gcggagacgg gtgagcctgc ctggcagttt gcagcgggag acccgcagat
     5221 cgcatcgagc gccgcggttg caggcggtgc cgtgtacatc gggggttcca gcgggaacgt
     5281 gtacgccctc gatgccctgt cgggggcgct cctctggaac tacacgacca gcgggccggt
     5341 ccagtccagt ccggcggtcg ttgacggtgt cgtgtacgtc gggagcgacg atggcaccgt
     5401 gtacgcgctt tctgcccccg atggcgccct cctctggaac ttcacgacgg gcggtgccgt
     5461 gcggtcgggc cccgcggtag caggcggtgt cgtgtacgtg gggagcgacg acggccgcct
     5521 ctatgccctc gatgcccaca ccggaaaccc cgtctggtcg taccaggccg gcagcgggat
     5581 atctgcgagc cctgcggtcg caggcggcgt cgtgtacgcg gggacttccg gctcccccgg
     5641 caccttcttt gcgctggacg cgtccaccgg ggacctgctc tgggatcact ctttcggaaa
     5701 acacccctgc tccgggagcc ctgcggtcgc acacggtatc gtgtacgccg ggtgcgatga
     5761 cggcggcctc tatgccttcg gatcgtcagg ggaaagcccg ccggcaggcg tgaccgggct
     5821 ccatgccgcc gcggcaacga acgactccat cacgtgggcg tggaccgatc ccgcgacagg
     5881 gggttttgca tccgtgcggg tcttcctcga cggggagttc cgggaagacg tcccggccgg
     5941 gacaggcacg tggaccgcga ccgggctttt gccggagaca ccccacacga tcggaacgag
     6001 gacagtctca gcttccggcc gcgtcaacgc cacctgggtg aaccacacgg catggaccgc
     6061 accggaggca gggcagaagg cctggaagtt ccgctcggac cccgggaaca cgggagcata
     6121 cgatgacggc gggacgaggc ccggaaacag cctcatctgg aagtccccca tcgagaacta
     6181 ttacggctcc ctcccggccg tggtggacgg ggtcgtttac gtcaacggca tctacgagat
     6241 gaatgccctc gatgccctga cgggaaaact cctctggtcc tccccgcacg gaggggggat
     6301 gagcagcccg gccgtggtgg acggggtcgt ctataccggc agcagtgaca ggaccatctg
     6361 tgccctcaac gcgacgacgg gcgccctcct ctggcagtac acgacggaaa agacagtcta
     6421 ttcgagcccg gcggtcgcag ggggtatcgt gtataccggt ggcacggacg aaaagctcta
     6481 cgccctcgac gccggaacgg gggcgcttct ctggactttt gacgccggtg cagaaatcag
     6541 gtcgagccct gccgtggccc gcggtgccgt gtacatcacg ggccgggacg ggacactctc
     6601 tgccctcaac gcgacgacgg gcgccctcct ctggagcttt gccaccggtg cggacctcgt
     6661 ctcgtcgagc ccggtcgtct ttggcaatac cgcctgtttc cgggccgctg aagggaacct
     6721 ctacgccctc gacgcgacca cgggggacct cctgtggacc gcacccgcga gccccgccga
     6781 ggagtccggg cctgccgttg ccggcggcat ggtctacacc ggggacggga acgggaccgt
     6841 ctctgccctc gatgcagcgg acggctcgcc catctggacc tacaccgccg gcgccccggt
     6901 ccggcacgga ccttccgttg caaacgggat cgtgtacgcc ggcagcaccg acgggaccat
     6961 ccatgccctc gacgccgcga ccggggacct cctctggaca tgggcgactg ccgagggagg
     7021 gtatacgagc ccggtcgttg caggcggtgt cctgtacacc acgggatcgg gcgggaccct
     7081 gtacgccctc gccacgctcc cggacggacc gccgccctgc gtcgcggacc tccacccggt
     7141 caccgtcaac ggggcagaga tcacgtgggc gtggaccgat ccccgggcaa tagggttctc
     7201 ccacgtccgg atcttcctaa acggcgtgtt ccaggagaac gtcacggccg ggacgggcac
     7261 atggactgcc cgcgggcttt ccccctcgac cgcgtacacc atcggcgtcc agacggtgga
     7321 caccgcggga cgggtgaacc agaccgtggt caccagcacg gcaacgacag gtcccctctc
     7381 ggtgacgcac ctcgacccct ccggtgccgt cgaaggcagc ccgtcgttcg tgctccacgt
     7441 gtacggaacg ggattttccc cctcgtccgt cgtctccttc gacggcgtgg agctggtgac
     7501 gcactttgaa aacgcaaccc acatctcggt ttccgtcccg cccgggttcg tgggccgtcc
     7561 ccgcagggca agcatcaccg tcaccgaccc cgcgaccgga caggcttcac aaaccgtggt
     7621 cttcccggtc accgacaacc cgacggcacg ggcacgggag ttccggtcgg accctgccaa
     7681 cacgggcatc tacgacgacg ggggacggag gcccgtcccc tccctcctct ggatgtgcca
     7741 gaccggggcc cgggtgacat cgagcccgtc ggtcgccggc ggcatcgtgt acatcgggag
     7801 ccaggaccgg aacctgtacg cgctgaacgc gacgaccggg gagatcctct ggaaatacga
     7861 cacgatggag cgcaatgaca tcgtgagctc gagccctgcg gttgcaaacg gcgtcgtgta
     7921 catcggcgga ctgaagacca aggtccatgc cgtggatgcg tacagcggcg acctcctgtg
     7981 gaaatacaag gtcccgatcc gcaccacctc gcgcagcggc atcagctcga gccccacggt
     8041 gacaggcggc accatcttca ttgccaacat ggacggggtc gtctacgcgt tcgacgagga
     8101 gacgggaacc ctcctctgga actataccgt cccgcaggcg accggcggtg aacggggaat
     8161 ctacgcgagc ccggcagtgg cggacggtgc ggtatacgtg ctgacgtatg acggggacct
     8221 gtatgtcctc gacgcatcga cgggaacgct cctctggagt tatgaaacgg caggtgacta
     8281 tggggcatac gcgagccccg cagtctccgg cggggtcgtc tataccggca gcgggttgaa
     8341 cggacccttc cgggccctcg atgcacggac cggggcactc ctctgggaag ccccgtcggt
     8401 cgtttccgcg tattcgagcc ctgcggttgc acacggcgtg gtctataccg gcagcatgga
     8461 caacagcatc tacgccctcg atgcgtcgga cgggacgatc ctgtggaact ttacgaccgg
     8521 ggataaggta tactcgagcc ctgcggttgc acacggcgtt gtctacgccg ggagcaatga
     8581 ctgcaacctc tacgccctcg atgcgtcgga cgggaggctt ctctggaact ttaccgtgaa
     8641 cgacggcatc atatcgagcc ccgcggtcgc tggcggtatc gtgtacttcg gctgcaacga
     8701 tggccgggtg tatgccctcg ggacactccc ggtggagccg ccgttcgcag actactccgc
     8761 gaacataacc gacgggaaag ccccgctcga cgtcctgttc accgacacgt cgatcggaat
     8821 cgtcacgtgg cggttctggg acttcggcga cgggacgacc gcgtgggcaa acgggacgca
     8881 gtccgtggtc cacacgtacg cgttccccgg caatttcctg gtctccctga cggcaggaaa
     8941 cgacggcggc caggacaccc ggaaaaaaac cccgctcatc catgtcacgc cttccgggca
     9001 gagaccggtg gcatggttca cggcattgcc catggttggg tacaggccgc tccaggtccg
     9061 gttcaccgac cggtcgatgg gctcgcccgt ggtatggcgg tgggactttg gcgacgggaa
     9121 cagctcggca gagaagaacc cggtccacac ctataccgcg gcaggcacgt tccgggtctc
     9181 cctgacggta ttaagcgccg gagggaggag ttcgtcctcg tccacggtct gggtgcggga
     9241 gagggctccc atcccgacga tcacgccggc cccgaccttc tccccgcacc cgacgataag
     9301 ccccgggccc acgatcccgc cccggccggg cgctccgccg gtagccttct tcaagatgag
     9361 cccgatcatg ggatcggccc cgctggccgt ggcgtttacc gacctctcct tcaacgcccc
     9421 aacgtcatgg tcctgggact tcggcgacgg gacgcagtcg gcggaaagga acccggtcca
     9481 cacgttcacg gaaaaaggtg tctacacggt gacgctttcc gtggagaacg cgtacggcaa
     9541 cagttccacg taccggaacg tgtacgtgcg gtagggggag gacaggtacg ggcggttgca
     9601 ggccggcagg gagggatcac gcggcatggg gggtgacggt ggcatgatgt ggacgcggat
     9661 cgatgtcccg acggggacac ggacccagtt catcgacatc acggggaccg ttgcggcaga
     9721 actggaaaaa gcccgggtac agagcggcac ctgcacggtg tacgtgccgc acacgacggc
     9781 gggcgtgacc atcaacgaga acgccgaccc ggacgtcgcc cgggacatcc tctcgggact
     9841 cgcccgcctc gtgcctgcga ccggcgatta ccggcacgcc gaggggaact ccgatgccca
     9901 catcaaggca tcgctcgtcg gctcctcggt caccgtcccg gtcatcggcg gacgcctcgc
     9961 cctcggtaca tggcaggcca tctacttctg cgagttcgac ggcccccgca accgccacgt
    10021 cctggtcggg atatcgggcg ggtagcggag ccggaacctg ccggcgtgcg tcccgcagca
    10081 ctcccggtcc gccggagcag gacagctccc ccggacactc ctgatccctc tctcttgcga
    10141 caaccaccgt gctgtgctcc gggacgatgg gcttctcacc ccggcaatcc ccgtgcccgg
    10201 ctccggaact gtggatccct ctctcctgcg ataatcaccg tgccatgctc cgggccaatg
    10261 gaccctctct cctgcgacaa cctccgtgcc gagatccggg acgatggaca ctccccctac
    10321 ctgagacaag ccccctgagc catgctccgg gccaatggac cctctctcct gcgacaacct
    10381 cagtgccgtg ctccgtgaca atgggcttct caccccggca atccccgtgc ggtgctccgg
    10441 aactgtggat cccccgttcc tgcgataatc accgtgc
//
LOCUS       DAOOJU010000045         9799 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_6178_length_9799_cov_4.922106, whole genome shotgun sequence.
ACCESSION   DAOOJU010000045 DAOOJU010000000
VERSION     DAOOJU010000045.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 9799)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9799)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9799
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6178_length_9799_cov_4.922106"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..2669)
                     /locus_tag="PK679_08595"
     CDS             complement(<1..2669)
                     /locus_tag="PK679_08595"
                     /inference="COORDINATES: protein motif:HMM:NF024270.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3821 domain-containing protein"
                     /protein_id="HPC56049.1"
                     /translation="MKEKNWNMIQGGLLAIAIVFLLFGVAAATPAIAHQFYGTVSNNL
                     GPAPAGSTIIAKINDNVRGSITVTTPGVFGGPDDWDDKLVVTADSSEIGQTIVFWVNG
                     YQATPTAVYQEGGKSAIALTYTVPVPTTTPTTGTPTPTPTPTIMPTPTPTPTPSINKV
                     PAGGDVFIGEEGLDITAGLGSAAQIAYWAPGTSTADQPSSILTVGTPTNFYVSPQTFV
                     GKTGPWYQWTGTKGPVAFNVVDPQISVKIWDNNGNKDVSGQTIPAGDYLNFRIETNAF
                     TVTQQRPNAALEGFLTIKVRAPDGTDYTYLYQDSTQTIPLTGIAPNDSAYYWVPVNPT
                     RGWFTDARTQSGTWIYKTGTYVVSAELNLNKMKENYKAPDGTTYTGKTVSPTMTCTLG
                     GFDTLKIWPSPATIIRGNTYMSIIEGRDTYYLLSVRDCSGMMTGIPCDQPPMIVHPQS
                     GVILDSTGYYRNTTVECSGCLKNVYDTVPHYPDNGLYYYAIIGYKDLPTTIINNKTYH
                     YVGWETSVDTKPGTYTIAIQEWKPYFDPNTPHAETTVTVTKGVVTFDTYVYGKPASSG
                     YMGETVKIKGTNTDSDVVYLFIKGPCTDCAGANMDGKGPVIKDHPLTFTTVSVRSDNT
                     WEYNWYTKNLTIDTGDYTIYASSRPDDWQALESAQCHECSPAGTSCAAWTKKPFTLNK
                     PTITGDIAPKTVKIVCCDPVSIVVSGTATGIMADTAEEFYSPVPIAYWVFGENKVAGK
                     KYIFNTKEVKCPDATFSIDLKDDINTLMLEPGTYWVVLQHPMFNHRLDIIPDKKINWW
                     NSIYKCNQTGDCGLYSYDTMREFVVSAVPFRWSKLFTIDGPDRLIGWQSISPYLIAGF
                     ENPAIDDTYKILTFKVESNTALQADFSGSPTYGP"
     gene            complement(2670..7214)
                     /locus_tag="PK679_08600"
     CDS             complement(2670..7214)
                     /locus_tag="PK679_08600"
                     /inference="COORDINATES: protein motif:HMM:NF016906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC56050.1"
                     /translation="MSLFSHKYPEKGRYSAFGLLVFSCLVMAATASTPIYGPMVIDQP
                     GTYVLMNDIVDYHGSVVYNGTEYWEPPFKILASDVVLDGNGHSITGVVNTTRSQWYLS
                     NDWVPDQDCVMVNPGLERVHVKNLRVLGGFDVAIDYYPTVDGLIENNEIRGNLYGIYT
                     LNTNNVDIRDNTIVDNVYDGILCQGYFNGQIENNIVNSNNERGIHLLNAYNNLIRENT
                     ANNNRIDGISLEAGSNNIFELNTANNNGINGILSEIGYNNTFERNTANQNALNGFNLT
                     WIAHSKVNTNTADTNGNNGIFILECGNYPSEGIVVADNHAWSNAWDGINLTHSSYHTV
                     SGNSVEQNSKAGISLNDFDLSPQGYDTTSNTIVNNTADHNGVYGIVSRGASGNTYRGN
                     TVRFNPTGIDIGEVFLTSAFLLSDGNELVENIVKNNALAGISVHGYDYARITSQNVLD
                     GNTVCDNDQIGVKLDYANANTLKNNCIAGNGNVGVLIKDSQDNNIYNNCFNNTENRAF
                     GGMIHYNTWNVLKQPGPNIVGGKYLGGNYWAQPDGQGHSQKFGHNEDEFIVNYYTVNG
                     DTNIDYFPLWNALNASFTTNPSPPSGTVPLTVTFTDTSAGYPTCWVWDFGDGFTSNES
                     NPTHTFTSDGSYTVTLTASRCIAKPCAGTSSMSTVVTVGPRADFTATPTVGTAPLIVS
                     FTDTSTVSGTSYSWSFPGGTPGTSTERNPVVRYDIPGTYSVSLTVTGSFGTKTEVKNN
                     YIEVRPSLVPVADFSASPLTGQRPLTVQFTDLSTNNPTSWYWTFGDGSYSTLQNPSHT
                     YAEPGTYTVSLTASNSGGSSTPAVKTDYITVAGPVADFTASPRTGIKPLTVYFTDLST
                     GNPTEWAWDFNNDGVTDSYAKNPTWTYPGDGTYTVKLTVDYSKAWADDETKTGYITVS
                     QVPAPEADFTGAPRTGIKPLRVDFTDLSTNNPTSWSWDFGDGSTSTEKNPSHTYQAPG
                     TYTVRLTASNEGGANSNTKNAYITVDNLPGPVADFSASPRSGTRPLTVDFTDLSTGNP
                     TGWEWDFNNDGTVDSMDQHPSWTYDAVGTYAVKLKVTNEGGSDTVIKTGYITVSNIPS
                     PVSEFTASPRSGTMPLTVNFIDQSTGNPVSWSWDFGDGSTSTERNPSHTYQTPGTYTV
                     RLNVTNNGGYNVNTKPAYIVVTDIALPTANFVASPLTGITPLTVQFTDTSTGGPTTWL
                     WDFGDGTTSTLQSPTHTFTSPRKYTVSLTVSNAKGVNAKIEPDYIYVRNTPPVAWFNA
                     TPTQGYAPLTVQFTDLSSGQGISSWNWDFGDGGTSTTQSPAYIYNVPGNYTVRLTVAN
                     DGGSNVATRTQYISVLPAPPAPPANVISLYPGWNFVSTPRKLADGHKTAQQVFGGVNM
                     GGRAILLYDGSTGMWKQLRATDEVLPLDGLWIYSVGRMDVTLQFDTSSIPVPPQKQLY
                     TGWNAIGISGVNQMSARDSLISIGSNWNMVIGYRNGATPEDPIIRGSTDPRYSDTRMM
                     YPTHGYWISMNANALYQGVL"
     gene            complement(7228..8631)
                     /locus_tag="PK679_08605"
     CDS             complement(7228..8631)
                     /locus_tag="PK679_08605"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC56051.1"
                     /translation="MVIIARWKEKIPQGKLFLSLVIVCLLSGIAAIAGAATVDFSATP
                     TSGNADLTVQFTDQTTATGNITGWLWDFGDGQTSNAQHPLHNYVTAGNYNVNLSVVED
                     GTPYSSVKVAYIQVDPLAVFSGTPTDGDAPLSVQFVDASKGFPKNWSWDFNGDGIIDS
                     YDQNPAPHVYSVAGRYNVSLTVRGNDFRTNTSVRAQYITVRPHNSFSADITSGKAPLT
                     VQFTDTSTGSPTSWNWNFGDGGTSTIQNPTHTFTTAGVYTVSMVATRAGVSGTPAATR
                     TITVYPDADFTATPRSGVYPLTVQFTDTSTGSPTSWSWNFGDGQTSTEQNPTHVYTTI
                     GAYKVTLTVSRGGLSDTEEKINYIFVNTPPRPLRANINGKTTFFSVDRIAGTAPFTAT
                     FYPYPSRLQKETTYTWDFGDGTSLVKTVPPGNRYWVPESVSHVYSIPGIYTVTLTIQN
                     SPTDYYTITMPNYVVVR"
     gene            complement(8986..9183)
                     /locus_tag="PK679_08610"
     CDS             complement(8986..9183)
                     /locus_tag="PK679_08610"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC56052.1"
                     /translation="MVSFTDLSTGNPTSWSWNFGDGTTSTLQNPTHTYTTPGTYTVAL
                     RITTASGAFRVVRSGIIRVLP"
     gene            complement(9406..9546)
                     /locus_tag="PK679_08615"
                     /pseudo
     CDS             complement(9406..9546)
                     /locus_tag="PK679_08615"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
     gene            9530..>9799
                     /locus_tag="PK679_08620"
     CDS             9530..>9799
                     /locus_tag="PK679_08620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56053.1"
                     /translation="MTVKSTIGAGGGTVVGAVVGTVVGAVVGTVVGTVVGTVVGTVVG
                     AVVGTVVGTVVGIVVGTVVGTVVGTVVGAVVGTVVGAVVGTVVGTV"
BASE COUNT         2063 a         2379 c         2812 g         2545 t
ORIGIN      
        1 ggcccgtacg tcggtgaacc ggagaagtct gcctggaggg cagtgttgct ctcgaccttg
       61 aaggtcagga tcttgtacgt gtcgtcgatt gccgggttct cgaaccctgc gatcagatat
      121 ggtgagatgc tctgccaccc gatcaaccgg tccgggccat cgatggtgaa gagcttgctc
      181 caccggaatg gtactgcaga taccacgaac tcacgcatcg tgtcatagga gtacaaaccg
      241 cagtcaccgg tctggttaca tttgtagatg gaattccacc agttgatctt tttgtcagga
      301 atgatatcga gcctgtggtt gaacatcggg tgctgaagaa ctacccagta cgttcccggt
      361 tccagcatga gcgtgttgat atcatccttg agatcgatgg agaatgtggc gtcgggacat
      421 ttgacctcct tcgtgttgaa tatgtacttc tttcctgcaa ccttgttctc cccaaagacc
      481 cagtacgcaa tcgggacagg tgagtagaac tcctctgcgg tatcggccat gattcccgtc
      541 gcagtaccgc tcaccacgat ggataccggg tcacagcaga cgatcttgac agttttcggg
      601 gcgatatctc cggtaatggt tggcttattc agggtgaatg gtttcttggt ccatgctgca
      661 caggatgtgc ccgcagggga gcattcatgg cactgcgcgc tttcgagggc ctgccagtcg
      721 tccggccggc tcgatgcata aatggtgtag tctccggtat cgatggtgag gttcttcgtg
      781 taccagttgt attcccaggt attgtcggac cggacagaga cagtggtaaa ggtcagcggg
      841 tgatccttga taacagggcc cttgccatcc atgttcgcac cggcacagtc cgtgcagggt
      901 cccttgatga agagatagac aacgtcgctg tcggtattcg tacccttgat tttgactgtc
      961 tctcccatgt atcccgaact tgccggcttt ccgtacacat aggtatcgaa ggtgaccacg
     1021 cccttggtga ctgtcaccgt tgtctctgca tgcggcgtgt tgggatcgaa gtaaggtttc
     1081 cactcctgga tggcaattgt atacgttcca ggtttcgtgt caacgctcgt ctcccaacca
     1141 acgtagtggt aggtcttatt attgatgatt gttgttggta aatccttgta accaattatt
     1201 gcgtagtaat aaagcccatt atcggggtaa tgggggaccg tgtcgtatac gttctttaag
     1261 catccactgc attccaccgt ggtattccgg taataaccgg ttgaatcaag tatcacacct
     1321 gattgtggat ggacaatcat ggggggctga tcacagggta ttcctgtcat catccctgag
     1381 cagtctcgta cagagaggag ataatacgta tcccgcccct ctatgatcga catgtaagta
     1441 tttcccctga tgattgttgc aggtgaaggc cagattttca gagtatcaaa tccccccagc
     1501 gtgcacgtca tcgttggtga tactgtcttt ccggtatacg tggtcccgtc aggagcttta
     1561 taattctcct tcatcttgtt gaggttaagt tctgcagaga caacgtaggt ccccgtcttg
     1621 taaatccatg tcccgctctg ggtgcgggca tccgtaaacc atccccgggt tgggttcacc
     1681 ggaacccagt agtacgcgga atcattgggt gcaattccag tcagtggaat tgtttgtgtg
     1741 ctgtcctggt agagataggt ataatctgtc ccgtcagggg cacggacttt tatcgtcagg
     1801 aacccttcga gtgcggcatt gggtctctgc tgcgtgactg tgaaagcatt ggtctctatc
     1861 cggaagttga ggtaatctcc agcaggaatt gtctggcctg aaacgtcctt atttccattg
     1921 ttatcccaga tttttacaga gatttgcgga tcgacaacgt taaatgcaac ggggcccttt
     1981 gttcctgtcc actgatacca tggtcctgtt ttccccacaa aagtctgcgg agagacatag
     2041 aaatttgttg gagttccgac tgtaaggata gagctgggtt gatctgcagt tgaagtgccg
     2101 ggagcccaat atgcaatctg ggcagcagaa ccgagccctg cagtaatatc cagcccctct
     2161 tcaccgatga acacatctcc gcctgccggg accttgttga tgctcggtgt gggagtcggc
     2221 gtgggagtcg gcattattgt cggtgtcggg gttggcgtgg gggttcctgt tgtcggcgtc
     2281 gttgtgggga caggcaccgt gtaggtcagg gcgattgcgc tctttccccc ctcctggtac
     2341 accgccgtcg gcgtcgcctg gtaaccgttc acccagaaaa cgatggtctg gccgatttcg
     2401 gaggaatcgg cagtaacgac aagcttgtca tcccagtcat ccggtccacc gaataccccc
     2461 ggcgtcgtga cagtgatgga cccgcggacg ttgtcattga tctttgcaat tatcgtgctt
     2521 cctgccggag ccggtccgag attattcgag accgtaccat agaactggtg tgcgatggct
     2581 ggtgtcgctg ccgctacacc gaacagcagg aaaacgatgg cgatggccag gagaccaccc
     2641 tgtatcatgt tccagttttt ttctttcatc tagagcaccc cctgataaag ggcatttgca
     2701 ttcatggata tccagtaccc gtgtgtcgga tacatcatgc gtgtgtcaga gtaccttgga
     2761 tcggtacttc cccggataat tgggtcttcc ggcgttgcac cgttacggta gccgatcacc
     2821 atgttccagt tgctgccgat cgagatgagc gagtccctcg cggacatctg gttgacaccg
     2881 gagattccta tggcattcca cccggtgtac agctgtttct gtggcgggac cgggatgctg
     2941 ctggtatcga actggagcgt gacatccatt cgcccgaccg aatagatcca gaggccgtcg
     3001 agaggtagta cttcgtcggt tgcccgtaac tgcttccaca ttcctgtcga cccgtcatag
     3061 agcaggattg ccctaccgcc catgttcacc cccccgaaga cctgctgggc agtcttgtgg
     3121 ccgtcggcaa gtttccgtgg ggtcgagacg aagttccagc cggggtagag ggagatcacg
     3181 ttggcgggcg gtgcgggagg tgcaggcagc acggaaatat actgggtcct cgtggcaacg
     3241 ttcgagcccc cgtcatttgc aacggtgagc ctcacagtgt agttgcccgg cacgttgtag
     3301 atgtaagccg ggctctgggt cgtcgatgtt cccccgtcac cgaagtccca gttccaggag
     3361 gagatgccct ggccggaaga gagatcggtg aactggaccg tcagcggtgc gtatccctgg
     3421 gtgggcgtcg cgttgaacca tgcgacgggt ggggtgttcc tgacatagat gtagtccggc
     3481 tcgatctttg cgttcacacc ttttgcgtta ctgacggtca ggctcacggt atatttccgc
     3541 ggggacgtga acgtgtgggt cgggctctgg agggtcgacg tcgtcccgtc gccgaagtcc
     3601 cagagccacg tggtcgggcc gccggtggag gtatcagtga actggactgt caaaggagtg
     3661 attccggtca ggggtgacgc gacgaaattc gcagtcggta atgcgatatc cgtcaccacg
     3721 atgtacgcag gtttcgtgtt tacattgtat cccccgttgt tcgtgacgtt caggcggacg
     3781 gtgtaggttc ccggtgtctg gtaggtgtgg gaggggttcc tctccgtcga tgtactcccg
     3841 tcaccaaagt cccaggacca ggaaaccggg tttcctgtcg actggtcgat gaaattgacc
     3901 gtcagcggca tggtgccgct ccgtggcgag gcggtgaatt ctgataccgg agacggaata
     3961 ttggaaacgg tgatataccc ggtctttatg accgtgtccg atcccccttc gtttgttacc
     4021 ttgagtttga cagcgtaggt cccgacggca tcataggtcc aggacgggtg ctggtccatg
     4081 ctatccacag ttccatcgtt attgaagtcc cattcccatc ctgttggatt gccggtggag
     4141 agatccgtga aatcgaccgt cagcggtcgc gtcccggagc ggggtgaagc agagaagtct
     4201 gcaacgggtc ccggtaaatt atcaacggtg atataggcat tcttcgtgtt ggaattggca
     4261 cccccttcgt tcgaggctgt caggcggacg gtgtaggttc ccggtgcctg ataggtgtgg
     4321 gaggggttct tctccgtcga ggttgatcca tctccaaagt cccacgacca ggatgtcggg
     4381 ttgtttgtcg agaggtccgt aaagtcaact ctcaggggtt ttatccctgt ccggggagca
     4441 ccggtgaaat cggcctctgg agcagggacc tgcgagacgg taatgtatcc cgtctttgtt
     4501 tcgtcatctg cccaggcctt ggaataatca acggtgagct tcaccgtgta ggtcccatcg
     4561 cccggatatg tccaggttgg gtttttcgcg taactgtccg taacgccatc gttattaaag
     4621 tcccaggccc actccgtcgg gttcccggtc gagagatcgg tgaagtacac ggtgaggggt
     4681 tttattccgg tccggggtga tgcggtgaag tctgcaacag gtccggcaac agtaatgtag
     4741 tcggtcttta cagccggagt actgcttccc ccgctgttcg atgcggtgag ggagacagtg
     4801 taggtcccgg gctcggcata ggtatggctt gggttctgga gtgttgagta agatccatcc
     4861 ccgaatgtcc aataccagga tgtcgggttg ttggtcgaga ggtcagtgaa ctggacggtg
     4921 agcggcctct gcccggtcag gggggaggcg gaaaagtctg cgacggggac aagcgaaggt
     4981 ctcacttcaa tataattatt cttcacttcc gtcttggtac caaagcttcc tgttaccgta
     5041 agtgagacac tgtaagtccc gggtatgtca tagcggacaa ccggatttct ttccgttgat
     5101 gtaccgggag tccctccagg gaaactccag gagtaactgg tcccactgac tgtcgaggta
     5161 tcggtaaaag aaacgatcaa tggtgctgtc cccacagtag gtgtcgcagt aaagtcagcc
     5221 ctgggcccga cggtgacgac ggtggacatg gaacttgtcc ctgcgcaggg ctttgcaatg
     5281 cacctgcttg ccgtgagggt gacagtgtag ctaccatcgg aagtaaatgt atgagtcggg
     5341 ttgctttcgt ttgaggtaaa cccgtcccca aagtcccaca cccagcatgt cgggtaccct
     5401 gcactggtat ctgtgaaagt gactgtcaga ggtacagttc cagatggagg agaggggttc
     5461 gtggtgaaac ttgcgttcag ggcgttccaa agcgggaagt aatcgatgtt ggtgtccccg
     5521 ttcaccgtgt agtagttcac gataaattcg tcttcattat gcccgaattt ctgggagtgc
     5581 ccctggccat cgggttgtgc ccagtagttg ccgcccaggt acttgccccc cacgatattg
     5641 gggccgggct gcttgaggac attccacgta ttgtagtgga tcattccgcc gaaggccctg
     5701 ttttccgtgt tattgaaaca gttgttgtag atgttgttat cctgcgaatc cttgatcagg
     5761 acaccaacat tgccgttccc tgcaatacag ttgtttttca gggtgttggc gttggcatag
     5821 tcaagtttca ccccaatttg gtcattgtcg cagacagtgt tcccatcaag gacgttctgg
     5881 ctcgttatcc tggcatagtc atatccatgg accgagatac cagccagggc gttgttcttg
     5941 acaatgtttt caaccagttc atttccatcg ctcaagagga atgctgaagt gaggaaaact
     6001 tctccgatat cgataccggt cgggttgaac cgaactgtat tcccacggta ggtgttgcct
     6061 gatgctcccc ggctgacaat tccatacact ccattgtggt cggcagtgtt attgacgatg
     6121 gtgttggaag tcgtgtcata tccctgcggg gaaagatcaa agtcattcag ggaaatacct
     6181 gctttactgt tttgttcgac ggagtttcct gagacagtgt ggtaagacga gtgcgtcagg
     6241 ttgataccat cccaggcatt agaccacgcg tggttatcgg ccaccacaat accttctgaa
     6301 ggataattac cacattcgag gatgaaaata ccgttattgc cgtttgtatc tgctgtgttt
     6361 gtattgacct tcgaatgagc gatccatgtc aggttgaatc cgttcaatgc gttctggttt
     6421 gcagtgttcc gctcgaaggt gttattatat cctatttccg ataagatacc gttaattcca
     6481 ttattgtttg cagtattcag ctcgaagatg ttattagatc ctgcttccaa tgagataccg
     6541 tcaattctat tattgtttgc agtgttttcg cggattaaat tgttgtaggc gtttaaaaga
     6601 tgaattcctc tttcattatt ggaatttaca atgttgtttt ctatttggcc gttgaaataa
     6661 ccctggcata aaatcccgtc atatacgtta tctactatag tattgtccct tatatcgacg
     6721 ttgttagtat ttaaagtgta aataccatag aggtttcccc ttatctcgtt gttctcgatc
     6781 agaccatcaa cggttgggta atagtcgatg gcaacgtcga aaccaccgag tactcttaag
     6841 ttcttgacat ggacccgttc caggccgggg ttcaccatga cacagtcctg gtcgggaacc
     6901 cagtcattgg agaggtacca ttgagaacgg gtggtattca cgacaccggt gatagagtgt
     6961 ccatttccat ccagcacaac atcagatgca agaatcttga aggggggttc ccagtattct
     7021 gtcccattgt agacgacgga gccgtggtaa tcgacaatat cattcatcag gacataggtc
     7081 cctggctggt cgatgaccat tgggccatag atcggtgtcg acgcagtcgc tgccatgaca
     7141 aggcaggaaa agacgaggag accgaatgcg gagtatctcc ccttttcggg atatttatga
     7201 gaaaatagag acatctttct cacctcctca ccgcaccacc acataatttg gcatggttat
     7261 cgtgtaatag tcggtcgggc tgttctggat tgtgagcgtc actgtgtaaa tccccggtat
     7321 ggaatacaca tgagatacgg attccggtac ccagtaccgg tttccgggtg gcacagtttt
     7381 tactagagat gttccatccc caaagtccca cgtatatgtt gtctccttct ggagtcgtga
     7441 gggataggga taaaatgttg cagtgaatgg tgctgtcccg gctatccggt cgacactgaa
     7501 aaaggttgtc ttgccgttaa tgtttgctct caagggacgg gggggtgtat ttacaaagat
     7561 ataattaatc ttttcttcag tgtcggagag tccgccccgc gaaaccgtca gggttacttt
     7621 atatgcaccg atagttgtgt agacatgagt tggattttgc tcggttgaag tctgtccatc
     7681 cccgaagttc caagaccacg atgtcgggct ccccgttgag gtatctgtaa actgaacagt
     7741 gaggggatag acgcctgatc ggggagttgc agtaaaatca gcatccggat aaaccgtaat
     7801 cgtccgcgtt gctgcaggag tcccgctcac tccagcacgg gttgccacca ttgagacagt
     7861 gtatacccct gcagtggtga aggtgtgggt cgggttctgg atcgtcgatg ttcctccgtc
     7921 accgaagttc cagttccacg atgtcgggct ccccgtggag gtatctgtaa attgaactgt
     7981 taatggcgct tttcctgatg ttatgtccgc actaaaacta ttgtggggac gcaccgtgat
     8041 gtactgagcc ctgactgatg tattggtccg gaaatcatta cccctgacgg tcaatgatac
     8101 attgtacctt ccggcaacag aatatacatg gggagccggg ttctggtcat aggagtcaat
     8161 aatcccatca ccgttaaagt cccaggacca gtttttggga aaccccttgg aagcatcaac
     8221 gaactggaca gagagcgggg catctccatc agtgggtgtc ccgctgaaga cagcaagggg
     8281 atcgacctga atatatgcca ccttcacgga ggaatacgga gtgccatctt ccacgacgga
     8341 taagttgacg ttatagttcc ctgcagtgac gtaattatgc agggggtgct gggcattgga
     8401 tgtctgcccg tccccaaagt cccatagcca tccggtaata tttcccgtcg ctgtggtctg
     8461 gtcggtaaat tgtactgtta aatcggcatt gccactcgtt ggtgttgcag aaaagtcaac
     8521 tgtcgctgca ccggcgatag ccgctatgcc tgacaggaga cacacaatca ccagagagag
     8581 gaacaacttc ccttgaggaa tcttctcctt ccatcttgca ataatcacca taacatgcca
     8641 ccttgatatc acacgatagc cagacgtgag agaatgatga atctataagc ctgccttgat
     8701 gccaccttat ctatccatca ctcggtcgct ctgacttccg cgttggatat aaaggagttg
     8761 tgttccttac actaatataa acatttcgta ataccagggg ccgaatttcc cgtggaagag
     8821 cgtgatgtcc cattttggcc ttcaggcggt ggcatatttc atctctctcc ctgagctagt
     8881 gatcaacgcc cgcttcagaa gaggattggc cgccggatca cccctgggac gaaaggaagg
     8941 tctggcctgc ccccattaag aaaaaggaaa tttttgatct ttttttcaag gcaggaccct
     9001 gatgattccg ctcctgacca ccctgaacgc tcctgatgcc gttgtaattc ggagcgcgac
     9061 cgtgtaggtt cccggcgttg tgtaggtgtg ggtcgggttc tgcagagtgg atgtcgtccc
     9121 gtcaccgaaa ttccatgacc aggaggtcgg gttccctgtt gagagatcgg tgaacgatac
     9181 catcaggggg accgggccgg atgcaggatt caccgagaaa tccggagcag gagttgctgg
     9241 cgggggtgtc tgcgtcggtg tgggagttat tgtcgggggg actgtcgtcg ggatggtcgt
     9301 gggcgtgggg ctgtcaaccc gtatcaactg gggatattca atactccctc ccccgttctg
     9361 ggtctttatc cgaagcctga cggtgtaccg tccgggcgtt gcatacgtat gcacggggtt
     9421 ttgttcggtg gatgaccccc cgtcaccaaa gtaccagaac caggagaagg gattgccggt
     9481 cgatatatcg gtgaaccgga cgaccagggg agcagggcct gaagaccgat tgaccgtaaa
     9541 gtccacaatc ggagccgggg gcgggacagt ggtcggggca gtggtcggga cagtggtcgg
     9601 ggcagtggtc gggacagtgg tcgggacagt ggttgggaca gtggttggga cagtggtcgg
     9661 ggcagtggtt gggacagtgg ttgggacagt ggttgggata gtggtcggga cagtggtcgg
     9721 gacagtggtt gggacagtgg tcggggcagt ggttgggaca gtggtcgggg cagtggttgg
     9781 gacagtggtt gggacagtg
//
LOCUS       DAOOJU010000046         9416 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_6432_length_9416_cov_15.639568, whole genome shotgun sequence.
ACCESSION   DAOOJU010000046 DAOOJU010000000
VERSION     DAOOJU010000046.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 9416)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9416)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9416
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6432_length_9416_cov_15.639568"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            417..499
                     /locus_tag="PK679_08625"
     tRNA            417..499
                     /locus_tag="PK679_08625"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:451..453,aa:Leu,seq:caa)
     gene            656..1906
                     /gene="hisD"
                     /locus_tag="PK679_08630"
     CDS             656..1906
                     /gene="hisD"
                     /locus_tag="PK679_08630"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HPC56054.1"
                     /translation="MFRPLDVDRWERERRSSLDEAKASAARIIEEVRKGGDAALLRMA
                     QKHEPECTSVRVMPEEVDAAYEEVEDRLIESLIEAEARITRFHELQKERSLWLEETEP
                     GIVLGVKTTPLDRVGLYVPGRRAAYPSTALMNAVPAKVAGVPEMCACSPPPVLPLTLV
                     ALDIAGVEEIYRIGGAQAVAAMALGTETIRPVQKIVGPGNVYVTAAKMLLREHAEIDF
                     PAGPSEIGIIADATANPSFIAIDILAQAEHDPDAACVLVTTDGAMAEKVGREVERLFA
                     RSPRKEIIEKALAHSGYVVAPDMDEAVRMMDRIAPEHLSIQVSDPLPVLSAVRHAGSI
                     FVGPYTPVAAGDYASGTNHVLPTAGYAKMYSGLNVGHFCRTSTVQIIGKEGLEAIGDI
                     IETIADAEGLHAHAESVRIRRKGT"
     gene            2201..3493
                     /gene="rbcL"
                     /locus_tag="PK679_08635"
     CDS             2201..3493
                     /gene="rbcL"
                     /locus_tag="PK679_08635"
                     /EC_number="4.1.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016984 - ribulose-bisphosphate
                     carboxylase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type III ribulose-bisphosphate carboxylase"
                     /protein_id="HPC56055.1"
                     /translation="MATDWYMDFVDTSYEPAENELVALFYFEPAAGISREEAAGRIAS
                     ESSTGTWTTLTSLPDRMRDLQATVFEIEGKYAWISYPLDLWEEGNAVQLLSGIAGNIF
                     GMKALRNLRLIDVTLPQAYISHFRGPHFGMEGIRTMMKVHGRPLTGAVPKPKVGFSAK
                     EHAQVAYETWMGGFDFAKDDENLTSTSFNRFDERVREMTRLRDRAEQETGETKSAFLN
                     ITADTETMKKRADLLAASGWNYAMIDVVVAGTAAVATMRDYCSDLGLAIHAHRAMHAA
                     FSRNRKHGISMQFLAKLMRLIGVSQIHTGTAVGKLSGTKREVALLANVLREQHVKAVP
                     HILLDQDWGRIKTAFPVSSGGLHPGLVPDVLGIYGCDLVLLVSGGIHGHPDGTRAGAV
                     ATMQAIEAWKEGVSLDEKAKTSRELARALEKWGYMRPK"
     assembly_gap    3550..3649
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <3650..4324
                     /locus_tag="PK679_08640"
     CDS             <3650..4324
                     /locus_tag="PK679_08640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56056.1"
                     /translation="FSFVPFGDIFFQPGEVQYTSSYNEQTLADHGVTTYTKSADIDTR
                     NKPVNQNNFEAEKTVTFIGDATGQMVSSESLALDTAGNYSRTKQSFLCPFAAGNGAVT
                     PQFCNIVAAGSDVSMKQVVLSTKAGDRFIAASADIPVALDYAVTINGPGSEPALGDVT
                     AYMNVHSKEGRMSKIYEEDEGDLIGIVYRPGLGSDLSYSEKTSASGAIWTFQKDMAYV
                     SGARRT"
     gene            4430..5011
                     /locus_tag="PK679_08645"
     CDS             4430..5011
                     /locus_tag="PK679_08645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC56057.1"
                     /translation="MASTPVRPPHEVFSAERAGHLDTRLRRLLYRPGRLAARYVRPGD
                     RVLDFGCGPGFFTREFAKRVGDGGRVFAVDLQEEMLHILRTGMETEGLISRITTHRCR
                     PDTIALPDACRGTFDVAFAIFVVHEVPDPRRLFSEIASLLKPGGTLFLSEPPLVVSGR
                     EFGDELRYAGEAGFSVRERRLFFVNRAAVLVKE"
     gene            5188..5547
                     /locus_tag="PK679_08650"
     CDS             5188..5547
                     /locus_tag="PK679_08650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="HPC56058.1"
                     /translation="MAEFTGACRLSGIRDGELRKVTVRGKEILLARRGDRVYATDVLC
                     PHLRADLSEGTLEGHILTCPMHGSQFDIRDGHVVRWTNLSGIILKFATRAIPPRPLTC
                     YPVRIEGDRVLVSVPWS"
     gene            complement(5646..6149)
                     /locus_tag="PK679_08655"
     CDS             complement(5646..6149)
                     /locus_tag="PK679_08655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HPC56059.1"
                     /translation="MSARILVAYASKKGSTAGIARAVARELESAGMTVDVTPLESVTS
                     LGAYDALVLGTPVYAGKFLADIPAFASRFSERIARIPVAGFVTGIAPVWPEAGDPDAI
                     TEKFVQAMAPGKPVAVTMFAGKFDPREHGILVRSLGKVMKIPAGDFRDWGSISAWARE
                     LPAKMGF"
     gene            6399..7178
                     /locus_tag="PK679_08660"
     CDS             6399..7178
                     /locus_tag="PK679_08660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56060.1"
                     /translation="MIPEPVQKGLKYLLIGAVIVFIAFFGYLVFLFNEAPSGSGVHHF
                     HYTITLSHPSTIDNVTILLPVPLLDGTPVLAESFLNRTVSGAPPGWNLSLEVVNGTPL
                     LAIRAATMVPEYHGYPIAIEPGESPLPPTRAPGKEYSADTPVLVPVSLGTIFPVNRTI
                     DTRNPVGKEPLFSPGGEFRLQEEYTLPYARGRAFGHTVPVYVSFSAGSPVALSITTSI
                     EGTNAVWKGGWVSHSYTDTVSVEVTEPGGWIDARGILVVEE"
     gene            7544..>7787
                     /locus_tag="PK679_08665"
     CDS             7544..>7787
                     /locus_tag="PK679_08665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RND family transporter"
                     /protein_id="HPC56061.1"
                     /translation="MKNPYEWLADRIIAHPRIVGAVAVIVVVIALYGLTLVTMETGSG
                     TYIDKATPRGATLTHYTDTYGSDAIMVIFESDDITDT"
     assembly_gap    7788..7887
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <7888..>9416
                     /locus_tag="PK679_08670"
     CDS             <7888..>9416
                     /locus_tag="PK679_08670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrophobe/amphiphile efflux-3 (HAE3) family
                     transporter"
                     /protein_id="HPC56062.1"
                     /translation="AFPVLIGIGIDYAIQIHSRLDEEARKSTLPDAIRTTVTKTGPAV
                     LIAMLATSMGFIAMKFGPIPMVGDFGITCTIGVVSCYLAALVIIPVFAMIIRYRPKTP
                     KGKLDDVSACELEWKGCEVPPVHQEGSRGKFIEKYDAFLGRVAYRIAKNPVPVLIFVF
                     LVAIIGFSLDNEVPISADEKTFVPPDMPALQYMNKVTRTMGSTSTIPVMVSSGNVLDP
                     VTVKWINDFGEYEVSHNDKVTGVTSIATLLARYNNGVLPSTEDEIRQVLARIPDGTKK
                     RYLNGNIEAVLEFSTVDLEIGQARSQIELIRDDVKWNTPPPGVTARVTGMTEMFAALM
                     DDIKNSKTTMTLLGFGFILGFLLLAYRRFHAVSPLLPIVAIVGWNGAIMYLLGLDYTP
                     LTAVLGSMTIGVASEYTVLIMERVDEEMARGLDLYTAIQTSVQKIGTAITVSGLTTVF
                     GFSALILSAFNIVSNFGITTVITVGFSLMGAILIMPAVIALLYRAGHPAASDAGKSAP
                     AA"
BASE COUNT         1834 a         2841 c         2731 g         1810 t
ORIGIN      
        1 cgggggatcg tctgcgacca tcctcggcat catcaaaaag agggaccggg acaaggacgg
       61 ggcccagaac gagctgataa tctggatcga tgtaaggaag ctgctggagg atatctccgg
      121 ggtttgctga caggaatccc cccccggaat cattccatca gggccccttt cccctccctg
      181 atacatcttt tttggaccta acctgttccc gggagttttt ccctgacccc cgcagcgatt
      241 tcgggcacgc catctctctg gcaaggagcc cgtgggactc gcacggggtt ttatgaaggt
      301 ccccttcttt ttccggggaa cgaaatacgt aacattgaaa ccgtttccag tcacgggtgg
      361 gacgggtgga tcgtgaagat ttatcctgct gcctgatcct ttcctattgt acaggagcga
      421 gtgtgactga gaggccaaaa gtgaccgact caagatcggt tctcgcagga gttcgcaggt
      481 tcgaatcctg ccactcgcat tcatcatcag gcaacccccg tttccttgcc ctgcgcgcct
      541 ttctcccctc ttccgatgca tctgcatcct cttttctgcc cctgaaccgt accggtcacc
      601 gtttcctccc gtgacaccac ccttaatctc tttccgggag aaacaggtgt tccgcatgtt
      661 cagaccgctt gatgtggatc ggtgggagag ggagcggcgt tcgagcctcg acgaggcaaa
      721 ggcctcggca gcccggatca tcgaagaagt ccggaaaggc ggggatgccg ccctcctccg
      781 gatggcacag aagcacgaac cggagtgcac gtccgtccgt gtcatgcccg aggaggtcga
      841 cgcggcctac gaggaggtcg aagaccggct gatcgagagc ctgatcgagg cagaggcgcg
      901 gatcacgcgg ttccacgagc tccagaagga gaggagcctc tggctcgagg agaccgaacc
      961 gggcatcgtg ctcggtgtca agacaacgcc gctcgaccgc gtgggactgt atgtcccggg
     1021 ccgccgggcc gcctatcctt ccacggccct gatgaacgca gtccctgcga aggtggcagg
     1081 agtcccggag atgtgcgcct gcagcccgcc gccagtcctc ccgctcaccc tggttgcgct
     1141 cgacatcgcg ggcgtggagg agatctaccg gatcggggga gcccaggccg tcgcggcgat
     1201 ggcactcggg acggagacga tccgcccggt ccagaagatc gtcgggccgg gcaacgtgta
     1261 cgtgacggcc gcaaagatgc tcctccggga acacgcggag atcgacttcc cggcaggtcc
     1321 aagcgagatc ggcatcatcg cggacgcaac cgccaacccg tccttcatcg cgatcgatat
     1381 cctcgcccag gcagagcacg acccggacgc cgcctgcgtg ctcgtgacga ccgacggggc
     1441 gatggcagaa aaggtcggca gggaggtcga acgcctcttt gcccggtccc cgcggaagga
     1501 gatcatcgaa aaggcactcg cccattccgg gtacgtggtc gcgcccgaca tggatgaagc
     1561 ggtccgcatg atggaccgga tcgcccccga gcacctctcc atccaggtga gcgacccgct
     1621 cccggtcctc tctgccgtca ggcatgccgg gtccatcttc gtcggtccct atacgccggt
     1681 cgccgccggg gactacgcgt cgggcacaaa ccacgtcctg cccacggcag ggtacgcgaa
     1741 gatgtactcg gggttgaacg tggggcactt ctgcaggaca tccaccgtcc agatcatcgg
     1801 gaaggagggt ctcgaggcga tcggagacat catcgagaca atcgcggacg ccgagggact
     1861 ccacgcccat gccgagtcgg tccgcatcag gcggaagggg acctgatatt tttcatggaa
     1921 atggctccgc cattttcctt ctctggccgg gtgtcccggg cagaaccatg ccatttttca
     1981 tgccggtctg gcactccgct cttcttggga cacccatcgt gaaaccgctg cggggggtcg
     2041 ctcgggggcg gcgggactgt tctcatgggg cgtgcggggg cggggccgcc cccgctctgg
     2101 ttcttcactc tcccaaccag atgagcgaag ggcccttttc ctctctcctc caccatttcc
     2161 attaagagac attcccccct ttcctgtaca gggaaagcac atggcaaccg actggtacat
     2221 ggacttcgtg gacacgtcct acgaacccgc agaaaacgaa ctcgttgccc ttttttattt
     2281 cgaaccggcg gcggggataa gcagggaaga ggccgccggc aggattgcgt ccgagagctc
     2341 gacagggacc tggacgacac tgacctcgct gccggaccgg atgagggacc tccaggcaac
     2401 cgtttttgaa attgagggga agtacgcatg gatctcctac cctctcgatc tctgggagga
     2461 gggcaatgct gtccagctgc tgagcgggat cgcgggaaac atcttcggga tgaaggcgct
     2521 ccggaacctc cggctcatcg acgtcaccct cccgcaggcg tacatctccc acttccgcgg
     2581 gccgcacttt ggcatggagg gtatccggac gatgatgaag gtgcacggca ggcccctgac
     2641 aggggcggtc ccgaagccga aggtgggttt ttccgcgaag gaacacgcac aggtcgcgta
     2701 cgagacatgg atgggcgggt ttgactttgc caaggacgac gagaacctga cctccacgtc
     2761 cttcaacagg ttcgacgaga gggttcggga gatgacgcgg ttgcgtgacc gggccgagca
     2821 ggagacaggg gagacaaagt ccgcgttcct caacatcacg gcagacacgg agaccatgaa
     2881 gaagcgggcc gacctgcttg cagcgtccgg gtggaactac gcgatgatcg acgttgtcgt
     2941 cgccgggacc gcggcagtcg cgacgatgcg ggactactgc tcggaccttg ggctggccat
     3001 ccatgcgcac cgggccatgc atgccgcctt ctcgcggaac aggaagcacg ggatatccat
     3061 gcagttcctc gccaagctga tgcgcctgat cggtgtttcc cagatccata ccgggacggc
     3121 ggtgggcaag ctctccggga caaagagaga ggtggccctc cttgccaacg tcctgcggga
     3181 gcagcacgta aaggccgtcc cccatatcct cctcgaccag gactggggca ggataaagac
     3241 cgcgttcccg gtctcctccg gggggcttca ccccggactc gtcccggacg tcctcggtat
     3301 ctacggctgt gacctcgtgc tcctcgtgag cggaggcatc catggccatc ccgacgggac
     3361 acgggcgggg gcagttgcca cgatgcaggc gatcgaggcc tggaaggagg gcgtatccct
     3421 cgacgagaag gcaaaaacct cccgggagct tgcacgggct ctggagaagt ggggatacat
     3481 gcggccgaaa tgagagagaa cggggagggg atctgccttg caggcaatcc ggcaggaaat
     3541 tctttttttn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt tttcgtttgt
     3661 tccatttgga gacatttttt tccagccggg agaagtccag tacacaagtt cgtacaatga
     3721 acagactctc gcagaccatg gggtaacaac atacaccaaa tccgcagata tcgatacgag
     3781 gaataaaccc gtcaaccaga acaatttcga ggcagaaaaa accgtcacct ttatcggtga
     3841 tgccacaggg cagatggtct ccagtgagtc ccttgccttg gacaccgctg gaaattacag
     3901 caggacaaaa caatctttcc tctgtccctt tgctgccgga aatggtgcag tgacacccca
     3961 gttctgcaac atcgttgcag caggaagcga tgtctccatg aaacaggtcg tcctttcgac
     4021 gaaagcaggc gaccgcttca tcgcagcatc tgccgatatc cccgttgcac tggattatgc
     4081 tgtcactatc aatggtcccg gttcggaacc tgctctcggg gatgtcaccg cgtacatgaa
     4141 tgtgcattca aaagagggca ggatgtcgaa gatttacgag gaagatgagg gggatcttat
     4201 agggatcgtt taccgccccg gtctcgggtc agacctctcc tacagcgaaa agacgtcagc
     4261 gagcggcgcc atctggacat tccagaagga tatggcgtac gtgtcggggg ccaggagaac
     4321 ctgagtatcc cccggcaaaa ttaccttttc tttttcattc ggttcgaaag ggactgattc
     4381 cggtcccccg tccgggaacc attattccgg tttgaaggaa tagttcacca tggcatccac
     4441 tccggtccgc ccgccgcacg aggtcttttc ggcagagagg gcaggacatc tcgatacccg
     4501 gctccgaagg ctcctctacc gccccggccg gctcgcagcc cgttacgtca ggcctggtga
     4561 ccgcgtcctc gacttcggct gcgggccggg ctttttcacc cgggagtttg caaaacgcgt
     4621 gggggatggc ggccgggtct ttgccgtcga cctccaggag gagatgctcc acatcctccg
     4681 gacaggaatg gaaacggagg ggctcatctc ccgcatcacg acgcaccggt gcaggccgga
     4741 cacgatcgct ctcccggacg cgtgcagggg gacatttgac gttgcctttg ccatcttcgt
     4801 ggtgcacgag gtcccggacc cccggaggct cttttcggag atagcatccc tcctgaaacc
     4861 gggagggacg ctctttctct ccgaaccgcc gctcgtcgtc tccggcaggg agtttgggga
     4921 cgagctccgg tatgcggggg aagccgggtt ttccgtgagg gaacggaggc tctttttcgt
     4981 caacagggcg gcggtgctcg tcaaggagtg acgggaagac gttctctcgt ccgggagccc
     5041 cctccccatt ccatgcccgg cagggagaaa acgaggggca caaaaccttt tagtcatccg
     5101 gcaggataac gtggcaggag aggcagagtt ccccgggaat gcacacggtg ggggaacgag
     5161 gggctgatga gggggttttg aaagggtatg gcagagttca ccggggcctg caggctctcc
     5221 ggcatccggg atggagagct gagaaaggtg acggtccggg gcaaagagat cctccttgcc
     5281 cggcggggag accgggtcta tgcaaccgat gtcctctgtc cccacctccg ggcggacctc
     5341 tcggaaggga cgctggaggg acacatcctc acctgtccta tgcacggatc gcagtttgat
     5401 atccgggacg ggcacgtcgt gcggtggacg aacctttcgg ggatcatcct gaaatttgcc
     5461 acgcgggcga tcccgccgcg ccccctcacc tgctacccgg tccgtatcga gggggacagg
     5521 gtccttgtca gtgtcccatg gagttgagtg aaaaggaaaa agggcgcttt caattcgcag
     5581 gtgtgccccc tgcaggattt tttccgtccg gaaaaagggg ggagacggaa gtgatccccg
     5641 gtgcgtcaga atcccatctt tgccggcagc tcacgcgccc atgccgagat tgaaccccag
     5701 tccctgaaat ctcctgccgg tatcttcatc accttcccga gggaacggac aagaattcca
     5761 tgctcccggg ggtcgaattt tcccgcaaac atcgtgacag caacgggttt tccgggagcc
     5821 attgcctgca cgaacttttc ggtgattgca tccgggtcac ccgcttccgg ccagaccggg
     5881 gcgataccgg tgacaaaccc tgcgacggga atcctggcga ttctttcgga gaatctgctg
     5941 gcaaacgccg gaatatccgc aaggaacttt cctgcataca ccggagtccc gagaaccagt
     6001 gcatcatacg ccccgaggga tgtgaccgat tcaagagggg tgacatccac cgtcatcccg
     6061 gcactctcga gttcacgtgc gacggcacgg gctatcccgg cagtcgatcc cttcttcgat
     6121 gcatacgcga caagaatccg tgctgacatg gtgatccttc tggcacaatg tgacctccct
     6181 gtatttgaag atacaacccc ggggaaaccg gcaggagagt gacacgctct ccggttcccg
     6241 cgggcattcc gggacatgtc cgcgacgggc ccgtggtgga accctccccg gtccgtgcct
     6301 tttgttcctg caccggagtt ttcgccggaa cgccccttgt gccatcccct ctttatttct
     6361 gcagggagaa ccgatcccct tgtgcggaga ttaaacccat gataccggaa ccggtgcaaa
     6421 agggattgaa atacctcctc atcggggcag tcatcgtgtt cattgcattt ttcggatacc
     6481 tcgtattcct attcaacgag gctccatcag ggagcggggt gcaccatttc cactacacca
     6541 tcaccctatc ccatccatcc acgattgaca atgtgaccat cctcctccct gtcccgctcc
     6601 tggacgggac acccgtcctg gccgaatcct tcctcaacag aacagtctcc ggggcacctc
     6661 ccggctggaa cctctcgctc gaggtcgtaa acgggactcc cctgctcgcc atccgggccg
     6721 ccacgatggt cccggaatac catgggtatc ccatcgcgat cgaaccggga gagagccccc
     6781 ttccccctac ccgtgctccc gggaaagaat actcggctga tacccccgtg ctcgtgcctg
     6841 tcagcctggg cacgatcttt ccggtgaaca ggaccatcga cacccgcaac ccggtgggaa
     6901 aggaacccct cttctccccc ggaggagagt tccggctgca ggaagaatac accctgccct
     6961 atgccagggg ccgggccttc gggcatactg tcccggtcta cgtgagtttt tctgccggct
     7021 ccccggttgc cctctccatc accacgagca tcgaagggac caatgcagta tggaagggtg
     7081 gctgggtctc ccattcctac accgatacag tgtctgttga ggtgacagag cccggcggct
     7141 ggatcgatgc acggggaatc ctcgtggtgg aagagtgaac ccgcgggaag ggaccccgga
     7201 tccctgtccc ccttttcccc gcgccacggg gaccgatcag ggcaccgggg tggtgcaggg
     7261 aaaccggtgg ggaccccttg caggaatccg gataattccc ctcttttcct gctacaggca
     7321 ttttatgcag ccatttttcc ggcgaggcat gcccctttcc ggtgcaatac ccttatagca
     7381 tcacgtcgcc cagatatgtt gtagtgaata tgacaactcc atggggccgt ggcaacactc
     7441 ccgcgtgcgg gccggggcat gtctttttcc agagggtgcc attccatccc gttccgggtc
     7501 agtttaccca tttacttccc ccccattgcc ggagcagggt agcatgaaaa atccctacga
     7561 gtggcttgcc gaccggatca ttgcgcatcc ccggattgtc ggggctgttg cagtcatcgt
     7621 tgtggtgatc gccctgtacg ggctcaccct cgtaacgatg gagaccgggt caggcaccta
     7681 tatcgataag gcaacccccc gtggcgcgac cctcacccat tacaccgata cgtacgggtc
     7741 ggatgcaatc atggtcatct tcgagtccga tgacatcacg gacacggnnn nnnnnnnnnn
     7801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7861 nnnnnnnnnn nnnnnnnnnn nnnnnnngct ttcccggtcc tgatcgggat aggcatcgat
     7921 tatgccatcc agatccattc ccggctggac gaggaggccc ggaagtcaac gctcccggac
     7981 gccatcagga ccacggttac caagaccggc cccgcagtgc tgatagcgat gcttgccacc
     8041 tcgatggggt ttattgccat gaagttcggg cccatcccca tggtggggga tttcggcatc
     8101 acctgcacca tcggcgtggt ctcctgttac cttgccgcac tggtcatcat cccggtcttt
     8161 gccatgatca tccggtaccg cccgaagaca ccgaagggaa agctcgatga tgtctcagcg
     8221 tgcgaacttg aatggaaagg ctgcgaggtt ccccccgtcc accaggaagg atcgcgtggt
     8281 aaattcatcg agaagtacga tgccttcctc gggagagtcg cctaccggat agccaaaaac
     8341 cctgtccccg tccttatctt cgtgttcctg gtcgcgatca tcgggttcag cctcgacaac
     8401 gaagtcccca tcagcgcgga cgaaaagaca ttcgtccccc cggacatgcc cgcgctccag
     8461 tacatgaaca aggtgacgag gaccatgggg tccacgagta ccatccctgt catggtgtcg
     8521 tcgggaaacg tccttgaccc ggtcaccgtc aaatggataa acgatttcgg cgagtacgag
     8581 gtctcgcaca acgacaaggt cacgggggtg acgagcattg ccaccctgct ggcacgctac
     8641 aacaacgggg tcctcccctc gacagaggac gaaatccggc aggtccttgc ccgcatcccg
     8701 gacgggacga agaagcggta cctgaacggg aacatcgagg cggtgctcga gttctccacg
     8761 gtcgaccttg agattgggca ggccaggtcc cagattgagc tcatccggga cgacgtgaag
     8821 tggaacactc ccccgccggg agtgactgcc cgggtcacag ggatgacgga gatgtttgca
     8881 gcgctgatgg acgacatcaa gaactccaag acgaccatga cgctccttgg gttcggcttc
     8941 atcctcggat ttctcctcct cgcgtacagg cgcttccatg ccgtctcgcc cctcctgccc
     9001 atcgttgcca tcgtggggtg gaacggagcc atcatgtacc tcctgggact ggactatacc
     9061 cccctcaccg cggtcctcgg ttccatgacc atcggggtgg cgtccgagta caccgttctc
     9121 atcatggaac gggtcgacga ggagatggcc cgcggcctcg atctctatac ggcaatccag
     9181 accagcgtcc agaagatcgg caccgcgatc acggtatccg gcttaacaac ggtctttggg
     9241 ttctcggctc tcatcctctc ggcgttcaac atcgtctcga acttcgggat caccacggtg
     9301 atcacggtcg ggttctccct gatgggcgcg atcctgatca tgccggcagt cattgccctc
     9361 ttgtaccgtg caggtcaccc ggcggcatcg gatgccggga agagtgcccc tgcagc
//
LOCUS       DAOOJU010000047         8569 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_7163_length_8569_cov_15.111698, whole genome shotgun sequence.
ACCESSION   DAOOJU010000047 DAOOJU010000000
VERSION     DAOOJU010000047.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 8569)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8569)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8569
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7163_length_8569_cov_15.111698"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(74..841)
                     /locus_tag="PK679_08675"
     CDS             complement(74..841)
                     /locus_tag="PK679_08675"
                     /inference="COORDINATES: protein motif:HMM:NF025053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C domain-containing
                     protein"
                     /protein_id="HPC56063.1"
                     /translation="METVRKGFGNTIVSCSRTERGIRERNEDACGIFSIPSPAGTLFL
                     LAVADGLGGHPAGEVASALAVRALSESVSLGAKALVVPDGASLRQLLATGFSHANARV
                     CQYAEEDPACLGMGTTLVAALLSERGEGVCGNVGDSRAYLVGNTIRRITRDHSEVQDL
                     VDRGLIPADAAEMHPLKNIVTRIIGRKGDEPDFYPVSLDGDCLLLCSDGLPDGISEGE
                     IHAIVTTTDFLGLCEALVAAARGRSRDNITVVAARRA"
     gene            complement(897..1901)
                     /locus_tag="PK679_08680"
     CDS             complement(897..1901)
                     /locus_tag="PK679_08680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HPC56064.1"
                     /translation="MDLLVELAGDHPVLPVLELDLIGPVREQSPRVAVVDCRFPGDIP
                     RLALTHVAMEFLGSCPAKKADFIELLEKLSLSSEKPFAGRVHKIPGTTMDAPQAELER
                     IIGSKVKGRVNLSCPEEEYRAVVSGSRCYLGRVIWRADPGHFSRRRPGDRPFFHPGVM
                     MPRMVRALVNISCTRAGEWMLDPFCGTGGMVLEASMIGIRAVGSDRDPFMARGSRKNV
                     PGEDIVLAEAGMLPFSRSSFDSVVTDLPYGQSVSIHARDLAELISGSLNEIGRVLKPG
                     RRAVIVCNREISGFPAGDLRIMTFCMQRVHKSLTRHIHVFVRKGRRDPQNSGQHSVII
                     "
     gene            complement(1937..3067)
                     /gene="dnaJ"
                     /locus_tag="PK679_08685"
     CDS             complement(1937..3067)
                     /gene="dnaJ"
                     /locus_tag="PK679_08685"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004076609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HPC56065.1"
                     /translation="MAGGDYYEILGIPRNADEKEIKKAYRNLARKYHPDVCKEPGAEE
                     KFKRINEAYSVLSDPQKRAQYDHLGHDTYTSASKGSYTGGGGFHGGGFSADFSGFGDI
                     FDFFGGGFSGSRPMGPQAGSDLLMRMQITLEEAVFGADREIEVSHTEACGHCNGTGSE
                     TKKLVPCPRCGGSGQMRQMSQTVFGQFVRMSTCTECRGRGRIPERKCSVCRGTGHTQV
                     HRRVTVHIPAGIDTGMRLRMEGFGEAGDYGAPNGDLFIEVVVRPHPRFRRSGDNLETD
                     IEVSPAQAVVGSTVEVETIDNKKVEMVIPPGIQHNTALKIPGEGVRRRGKPGDLLVRV
                     KIVIPRQPKAEVRSLYEKILDLEGHRPPDSKKGFFSTFMGKK"
     gene            complement(3073..4929)
                     /gene="dnaK"
                     /locus_tag="PK679_08690"
     CDS             complement(3073..4929)
                     /gene="dnaK"
                     /locus_tag="PK679_08690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HPC56066.1"
                     /translation="MAKEKILGIDLGTTFSCMAIMEAGKPIVIPNAEGQRTTPSVVAF
                     TKDGERLVGSLAKRQAITNPTRTIQSIKRKMGTSEKVKIDDKSYTPQEISAMILQKLK
                     ADAEAYLGEKITKAVITVPAYFNDAQRQATKDAGRIAGLEVMRIINEPTASALAYGID
                     KENDATVLVYDLGGGTFDVSILTLGDGVFEVKATAGNNHLGGDDFDNRIIDYLVEEFQ
                     KKEGINLRSDPIAMQRLRDAAENAKIELSQKMKTNINLPYITTGPDGPKFLDIDLTRA
                     KFEQLIGDLVESTVIPVKQALSDAKLTPDQIDHVLLVGGSTRVPLVQETVRKILGKEP
                     DKGINPDECVALGAAIQGAVLSGETKDIVLLDVTPLTLGIETLGGIATKLIERNTTIP
                     TRKSQIFSTAADGQTSVEIHVVQGERALAKDNFTLGRFTLTGIPPAPRGVPQIEVTFD
                     IDANGIIHVSAKDLGTGNEQAITIKGDKKLSEDEIKRMVEDARKFEEEDRKKREEIEL
                     RNSADNAIFTAEKLLKDNAATIEPADREKVESGIADLRKALGGDQVDDIKAKMESLTE
                     SVYNITTKIYQKAQAERQAQAGASGNPGGGPGTKAEPKDDTVVDADFKVKDE"
     gene            complement(4931..5470)
                     /locus_tag="PK679_08695"
     CDS             complement(4931..5470)
                     /locus_tag="PK679_08695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - chaperone binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HPC56067.1"
                     /translation="MDPSQEEEFIDSDEKKEQESSTKGDGTSPSGGPVPEDLQKKYEE
                     LNDRFLRLAADFDNYRKRMERETRERTRYALEAFATELLEVADNFERALSADPASAKE
                     GLEQIHKLFCSIMERHGVVPIKAKGRKFDPAEHEAIACVPSDEDEGTVIDEVCCGYRM
                     HDRIIRVAKVAVAKKKESE"
     gene            complement(5638..6969)
                     /locus_tag="PK679_08700"
     CDS             complement(5638..6969)
                     /locus_tag="PK679_08700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HPC56068.1"
                     /translation="MREPAVRKTLYWCDACNLPLLGRKCACGTEGRAIPLLRPYDARP
                     ALQADREIITGLLRRHFGTGDLPAVVILNKTGGRDRNDLIIANGERFGWLSFDPGSKR
                     YSLELAFGAVSCLLHAATKGVIGLSDVPDAYRDVAQGRRIGGKRYPVPGHLPEGPVLI
                     QWEGHAAVGTCRGGFLKVKEAGKYSPSHRPDPDWDRVISANISTLKNLERSAIRFIRH
                     EASGASCVTVSFSGGKDSTVAMELARRAGYTDAFFVNTGMEFPETLGFVKSLGIPHIL
                     HAGDFWREIEKAGPPHKDDRWCCERQKLSPVREWMKGKGECITIQGNRWYESFARSGL
                     APVARNPFYRLQVNISPIRNWRALEVFLYSWWRKLPQNPLYALGFERVGCWMCPAMLE
                     SEWELVRRIHPDLHRTWMDFLMEWGRKAGIDREAILAGAWRWKKTPPKMHG"
     gene            7084..8568
                     /gene="purH"
                     /locus_tag="PK679_08705"
     CDS             7084..8568
                     /gene="purH"
                     /locus_tag="PK679_08705"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HPC56069.1"
                     /translation="MKWALLSVWNKEGIVDLASLLHRHGINLMSSGGTGALLKEAGIP
                     FTEVSEYTGFPEMMDGRVKTLHPRVHGGLLGRRGVDDRIMQEQGIVPIDLLVVNLYPF
                     AEMSAQSLPLERLVEYIDIGGPALIRAAAKNYRDVAVISDPGQYPLVARALEHGGFTP
                     EERLALARAAFARTAAYDAAISNYLHGLGKDFPDILTLQFSNGRTLRYGENPHQKGAV
                     YGTAGIAGQQTIQGKQMSYNNYLDLHAAAGLVREFSEPAAVVVKHNNPCGAAVGSTLL
                     EAYILARDTDPVSAYGSVVALNREVDSALAEEISRTFVEVVAAPSFSSDSREILRKKE
                     NLRLLSLPEPRVSREIRTIDGGILVQETPPYQEEWKVVTDRDATPGEFQAMRFAWKVC
                     AHTKSNAIVFAGNNRTLGIGAGQMSRVDAAKIAIEKSLSSLVGSAVASDAFLPFPDTL
                     EVAAAAGATALVQPGGSIRDREVIDAANRLDMAMVFTGIRHFRH"
BASE COUNT         1626 a         2660 c         2341 g         1942 t
ORIGIN      
        1 ctattccccc atgcagtcac attcccggct ttttttccgt catgcagcac gcgcacgacc
       61 tttccctgcg gactcatgca cgccgcgctg caacgaccgt aatattgtcc ctgctcctgc
      121 cacgcgccgc tgcgaccagt gcctcgcaga ggcccaaaaa atcggtcgtg gtgacgattg
      181 catggatctc cccttcgctg ataccatcgg ggagaccgtc ggaacagagg agaagacagt
      241 cgccatccag tgaaacggga taaaagtcag gctcgtctcc ctttctcccg atgatccggg
      301 tcacgatgtt tttcaggggg tgcatttctg ccgcatccgc cggaatgagg ccccggtcca
      361 cgaggtcctg cacctcggag tggtcccgcg ttatcctgcg tatggtattg cccaccaggt
      421 aagcccggct gtccccgaca tttccacaga caccttcacc cctttccgaa agaagggcag
      481 ccacaagtgt cgttcccata cccaggcagg caggatcctc ctccgcgtac tggcacaccc
      541 gcgcatttgc atgggagaaa ccggtcgcga ggagctgccg gagagacgcc ccgtccggca
      601 cgacaagtgc ctttgcaccg agcgaaacgg actcggaaag tgccctgaca gccagtgcac
      661 tggcgacttc tcccgcgggg tgacccccga gaccgtctgc aacggcgagc aggaacaggg
      721 tccctgccgg ggacggaatg gagaagatac cgcatgcgtc ctcgtttctc tccctgatac
      781 cgcgttcggt cctggaacag gaaacgatcg tgttcccgaa acctttcctc actgtttcca
      841 ttccttcccc cgggccccgc tggtcaatcc aggatctatg tgatggctcc tgtcatttaa
      901 atgattactg aatgctgacc ggagttttgc gggtcccttc ttcctttcct gacgaaaacg
      961 tggatatgac gggtaaggct cttgtggaca cgctgcatgc agaaagtcat gatcctgagg
     1021 tctcctgccg gaaatccgct gatttcccgg ttacagacga tcaccgccct ccgcccgggt
     1081 ttcagcaccc tccctatctc gttgagcgac ccggagatga gctccgcgag atcccgtgca
     1141 tggatcgaga ccgattgacc gtagggaaga tcggtgacta cagagtcgaa cgaggaccgc
     1201 gagaagggca gcatccctgc ctcggcaagg acgatatcct ctccggggac gtttttcctg
     1261 ctcccccggg ccatgaaagg gtcacggtca cttccaaccg cccgaatgcc gatcatcgat
     1321 gcttcaagga ccatcccccc cgtcccgcag aagggatcga gcatccattc ccctgccctt
     1381 gtacacgaga tgttgacgag tgcccgcacc atgcggggca tcatgacacc gggatgaaaa
     1441 aaaggcctgt cgcctggcct gcgcctggaa aagtgaccgg gatcagccct ccatatgaca
     1501 cgtcccaggt aacagcggga accggacaca acagcacgat actcctcctc cgggcaggac
     1561 aggttgaccc tgcctttcac tttcgagccg ataatccgtt cgagttcggc ctggggggca
     1621 tccatcgtgg ttccgggaat cttgtgaacc cggccggcaa acggcttttc ggaggataag
     1681 gagagttttt cgagcaactc aatgaaatca gccttctttg ccgggcagga gccgagaaac
     1741 tccattgcca cgtgggtgag ggcgagcctt gggatgtctc ccgggaaccg gcaatcgaca
     1801 acggcaaccc gtggcgactg ctcgcgtacc gggccgatga gatccagttc gaggacgggg
     1861 agaacgggat gatcaccagc cagttccacg aggagatcca tgaaaagtat ttatttccgg
     1921 atgagaaaaa acagggtcat ttcttcccca tgaaggtcga gaagaagccc ttctttgaat
     1981 cgggtggcct gtgaccctcc agatcgagta tcttttcata caggctcctg acctcggcct
     2041 tcggctgccg ggggatgacg atctttaccc tgacgaggag gtctcccggt ttacccctgc
     2101 gacggacccc ctccccgggg atcttcaggg ccgtattgtg ctgtatcccg ggcggaatga
     2161 ccatttccac ctttttattg tcaatcgttt cgacttcgac tgtcgaaccg acgaccgcct
     2221 gggcagggct gacctcgatg tccgtctcga ggttatcgcc cgaccgtctg aaccggggat
     2281 gcgggcggac gacgacctcg atgaagagat caccgttcgg agcaccgtaa tcccccgctt
     2341 ccccaaaacc ctccatccgc aggcgcatgc cggtatcgat accggccggg atgtggacag
     2401 tcacccgccg gtgcacctgg gtatggcccg tgcccctgca aacagagcat ttcctctcgg
     2461 gaatgcgccc cctcccgcgg cactcggtgc acgtgctcat ccggacgaac tggccgaata
     2521 ccgtctggct catctggcgc atctggccgg aacccccgca tctcgggcag gggaccagtt
     2581 tcttcgtctc gcttccggtc ccgttacagt ggccgcacgc ttccgtgtgg ctgacctcga
     2641 tctccctgtc agccccgaac acggcttctt cgagcgtgat ttgcatcctc atcaggagat
     2701 cggagccggc ctgcggaccc atcgggcgtg accctgaaaa accacccccg aaaaagtcaa
     2761 atatgtctcc gaaaccggag aagtctgctg aaaaccctcc gccgtgaaag ccaccgccac
     2821 ctgtatagga gcccttcgag gcactcgtgt acgtgtcgtg gccgaggtgg tcatactgtg
     2881 ccctcttctg gggatccgag aggacactgt atgcctcgtt gatccgcttg aacttctcct
     2941 ctgcccctgg ttccttgcag acatcggggt ggtacttccg ggcgaggttc ctgtaggcct
     3001 tttttatctc cttctcgtcg gcgttcctgg ggatacccag gatctcgtag tagtcacccc
     3061 cggccatggg gctcactcgt cttttacctt gaagtcggcg tcaacaacgg tatcgtcctt
     3121 tggttcagcc tttgtgcccg gtcctccacc ggggttgccc gatgccccgg cctgggcctg
     3181 gcgctccgcc tgggccttct ggtaaatctt tgtcgtgata ttgtagaccg actcggtgag
     3241 gctctccatc tttgccttta tatcgtcgac ctgatcccct ccgagggcct tgcggaggtc
     3301 ggcaattccg ctctcgactt tctccctgtc agcaggctca atcgttgcgg cgttgtcctt
     3361 gaggagcttt tctgccgtga aaatggcatt gtccgcggag ttacggagct cgatctcctc
     3421 gcgcttcttc ctgtcctctt cttcgaactt cctcgcgtcc tcgaccatcc gcttgatctc
     3481 gtcctcggag agctttttat cgcccttgat tgtgattgcc tgctcgtttc ctgtcccgag
     3541 gtcctttgcc gaaacgtgga taatcccgtt tgcatcgata tcgaatgtca cctcgatctg
     3601 gggaactccg cggggagcgg gtgggatgcc ggtcagagtg aacctcccga gggtgaaatt
     3661 gtcctttgcg agcgccctct cgccctggac cacgtggatc tcgacactcg tctgcccatc
     3721 ggcagccgtc gagaatatct ggctcttgcg ggtcggaatg gtcgtgttcc tctcgatcag
     3781 cttggtggca atccccccaa gggtctcgat cccgagtgtc agtggcgtca catcgaggag
     3841 gacaatatcc tttgtctctc ccgagagaac tgctccctgg attgcagcac caagagccac
     3901 gcactcgtca gggttaatac ccttgtccgg ctccttgcca aggatcttcc tgaccgtctc
     3961 ctggacaagg ggcacccgcg tcgaaccacc gacgaggagg acgtgatcga tctggtcggg
     4021 tgtcagcttg gcatcgctca atgcctgctt gacggggatc accgtggact ccacgaggtc
     4081 gcctatgagc tgctcgaact tggccctcgt caggtcaatg tccaggaact tggggccgtc
     4141 cgggcccgtg gtgatgtagg ggaggttgat gttcgtcttc atcttctggg agagttcaat
     4201 ctttgcgttc tctgccgcat cccgcagcct ctgcatggct atcgggtccg acctcaggtt
     4261 aataccctcc ttcttctgga attcctcgac aaggtaatcg atgatccggt tgtcgaagtc
     4321 atccccgccg aggtggttat tcccggcagt tgctttcacc tcgaagacgc catcgccaag
     4381 cgtcaggatg gagacatcga acgttccacc gccgaggtca tagaccagca cggtcgcatc
     4441 gttctccttg tcgatcccat atgcaagtgc gctcgccgtg ggttcgttga tgatgcgcat
     4501 gacttcgagc cctgctatcc tgccggcgtc cttcgtggcc tggcgctggg catcgttgaa
     4561 ataggcaggg accgtgatga ccgccttcgt tatcttctcc ccaaggtagg cctctgcatc
     4621 cgccttgagc ttctgcagga tcatggccga gatttcctgg ggagtgtaac tcttatcgtc
     4681 gatcttcacc ttctcgctcg tccccatctt cctcttgatg gactggatgg tccgcgtggg
     4741 attggtaatc gcctgcctct tggcaaggct cccgacgagt ctctccccgt ccttcgtgaa
     4801 tgccacgacc gaaggggtcg tccgctgtcc ttctgcgttg gggatgacga tcggttttcc
     4861 ggcctccatg atggccatgc acgagaaagt ggtccccagg tcgattccga gtatcttttc
     4921 ctttgccata ttactctgac tccttcttct ttgcgactgc cacttttgca accctgatga
     4981 tcctgtcatg catgcggtaa ccgcagcaga cctcgtctat gaccgtccct tcgtcctcgt
     5041 ccgacggaac acatgcaatc gcctcgtgct ccgcgggatc aaacttcctg ccctttgcct
     5101 tgatcgggac aaccccgtgc ctctccatga tggaacagaa gagcttgtgg atctgttcca
     5161 ggccttcctt cgcggatgcc ggatcagccg agagagcccg ctcgaagtta tccgcaactt
     5221 ccaggagttc ggttgcgaat gcctccaggg cgtacctggt ccgctcccgg gtttcgcgtt
     5281 ccattctctt cctgtagttg tcgaaatctg ccgcaaggcg caggaaccga tcgttcagtt
     5341 cctcgtactt tttctggagg tcttccggga ccggtccccc ggaaggggag gttccatccc
     5401 ctttcgtgga tgattcttgc tccttttttt catcagagtc aataaattcc tcctcttggg
     5461 acggatccat acaactatcg attatctatt gcattgtagt tctatatata attaactata
     5521 ttttttatat gctgaccgga ccagggacta gctcgcccgg aaaaatgatt ggtccggaaa
     5581 aagtgagtga cggaaaaacc tgactgcttc ggtttgatcc catcaggcgt tgcccaatca
     5641 cccgtgcatc ttgggagggg tttttttcca cctccaggca cctgcaagga ttgcttccct
     5701 gtcgatcccc gccttccttc cccactccat caaaaaatcc atccacgtcc tgtgaaggtc
     5761 cgggtgaatc cggcgcacga gttcccattc gctctcgagc atcgcggggc acatccagca
     5821 ccctacccgc tcaaaaccga gagcatagag ggggttttgc gggagctttc tccaccagga
     5881 atagaggaag acctcaagag ccctccagtt ccgtatcggt gatatgttga cctggagacg
     5941 gtagaaggga tttcgtgcga ccggggcaag cccggatcgg gcaaacgatt cgtaccacct
     6001 gttaccctgg atcgtgatac actccccttt ccctttcatc cattccctca cgggtgagag
     6061 tttctggcgt tcacagcacc agcggtcgtc cttgtgcggc gggccggcct tctctatctc
     6121 ccgccagaaa tcccctgcat gcaggatatg gggtatgccg agtgacttca cgaagccaag
     6181 tgtctcggga aactccattc ccgtattcac aaagaaggca tccgtgtatc ccgcacgacg
     6241 ggcaagctcc atcgcaacag tgctgtcctt tccccctgaa aaggagaccg tcacgcacga
     6301 tgcacccgat gcctcgtgcc tgatgaaccg gattgcagac ctctcgaggt ttttcagggt
     6361 ggatatgttt gcggagatca cccggtccca gtccgggtcc gggcgatgcg agggggaata
     6421 ttttccggct tcctttacct tcaggaaccc tcccctgcag gttcccaccg ctgcatgccc
     6481 ctcccactgt atcaggacgg gtccttccgg gagatgtccg ggtaccgggt acctctttcc
     6541 accaatacgc ctcccctgtg caacatcccg gtatgcatcc ggaacgtccg aaagcccgat
     6601 gacacccttt gtcgctgcat gcaggaggca tgagactgca ccgaacgcga gttcgagtga
     6661 atatctcttt gacccgggat cgaaggataa ccagccgaac cgctctccat tcgcaatgat
     6721 caggtcgttt ctgtccctcc cgcctgtctt gttgaggatt accaccgcag ggagatcccc
     6781 tgtcccgaaa tgacgccgga ggaggccggt gataatctcc ctgtctgcct gaagtgccgg
     6841 gcgggcatcg taaggacgca ggagagggat tgcccggcct tccgtcccgc aggcgcattt
     6901 cctgcccaga agggggaggt tgcacgcatc gcaccagtag agggtcttcc tgacagccgg
     6961 ttctctcatt cctgcatgag aggtacttcc ccaccgggga taatggttga gactccggac
     7021 ccccgcacct cttccccgtg attgtgcatc agtctcatta ccccttcccg cgtaccattg
     7081 actatgaagt gggcactcct ctccgtatgg aacaaggaag gtatcgtgga tcttgcatct
     7141 ctccttcacc gtcatggcat aaacctcatg agctcgggtg ggaccggggc ccttttgaag
     7201 gaagcaggca ttccatttac cgaggtctcg gagtacacgg gttttcccga aatgatggac
     7261 gggcgggtca agacactcca cccgcgggtg cacggcgggc tcctcggcag gaggggtgtc
     7321 gatgaccgca tcatgcagga gcagggtatc gttcccatcg acctcctcgt cgtcaacctc
     7381 tacccctttg cagagatgtc ggcacaatcc ctcccactcg agcgtctggt ggaatacatc
     7441 gatatcggcg ggccggcact gatcagggcg gctgcaaaga actaccgcga cgttgccgtc
     7501 atttccgatc ccggacagta tcccctcgtt gcacgggccc tggagcatgg cggttttaca
     7561 ccggaggaga ggctggccct cgccagggcc gcctttgcaa ggactgccgc atacgacgcc
     7621 gcgatcagca actatctcca cgggcttgga aaggactttc ccgatatcct gacactccag
     7681 ttttcgaacg gcaggaccct gcggtacgga gaaaatcccc accagaaagg ggcagtgtat
     7741 ggtacagcag ggattgccgg gcagcagact atccagggga aacagatgtc ttacaataac
     7801 tacctcgatc tccatgcagc cgcagggctc gtccgggagt tttcggagcc tgccgccgtg
     7861 gtcgtcaagc acaacaaccc ctgtggagcc gcggtaggaa gcacgcttct cgaggcatac
     7921 atcctggcga gggataccga tccggtctcg gcttacggtt ctgtggtcgc cctgaacagg
     7981 gaggtggaca gcgcacttgc ggaagagatc tcgcgcacgt ttgtcgaggt cgttgccgca
     8041 ccgtctttct cgtcagattc ccgcgaaatt ctcaggaaaa aggagaacct gcggttgctc
     8101 tccctgcccg aaccacgtgt gtcccgcgag atcaggacga tagacggggg aatcctcgtc
     8161 caggagactc ccccctacca ggaggaatgg aaggtggtca ccgatcgcga tgcgactccc
     8221 ggggaattcc aggcaatgcg ttttgcatgg aaagtctgtg cccacacgaa gagtaacgcg
     8281 atcgtctttg caggcaataa caggacactc gggatagggg ccggccagat gagccgcgtg
     8341 gacgctgcaa aaattgccat cgagaaatcg ctctcctccc tcgttggctc cgcggttgct
     8401 tccgacgcct tcctgccatt ccctgatacg ctcgaggttg cagccgctgc aggggcaacc
     8461 gccctcgtcc agccgggtgg atccatccgt gaccgcgagg taatcgatgc tgccaaccgg
     8521 ctcgacatgg ccatggtgtt cacgggcatc aggcatttcc ggcattaaa
//
LOCUS       DAOOJU010000048         6862 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_9194_length_6862_cov_14.954459, whole genome shotgun sequence.
ACCESSION   DAOOJU010000048 DAOOJU010000000
VERSION     DAOOJU010000048.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 6862)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6862)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6862
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9194_length_6862_cov_14.954459"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            83..1126
                     /locus_tag="PK679_08710"
     CDS             83..1126
                     /locus_tag="PK679_08710"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56070.1"
                     /translation="MVLEGSLRFDSAEGADAFIRYLRKKGCKAHKKTVAVFFESEELE
                     GTIDSFIAFLGDLLGREDVEEDNGGMDEEEEGRKCDRASVENRLENLEKARARLENLF
                     STCAEGDVALTEDDLHRHGDDFFEHMARAVFPVMQRNLAERGIDLPPRDETRDVSDDQ
                     VEEAGVFLTVFDILDENGLLEKDREGKYRLARKVPVEQCRMKISTFGLGDFDDGDLEP
                     YGIVPCTSIVMDSQHEVVMDGTVVTEFSADDLDEGLAGLDADAESLDAFFSDFELKRL
                     AVIALIEVVGEAGKISFEDLRERLTEYVLRSDKVEAPVKVTLEQDFLSSLVAELRKQG
                     YLAGSQENIRLAG"
     gene            complement(1281..1610)
                     /gene="eif1A"
                     /locus_tag="PK679_08715"
     CDS             complement(1281..1610)
                     /gene="eif1A"
                     /locus_tag="PK679_08715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004037410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor eIF-1A"
                     /protein_id="HPC56071.1"
                     /translation="MNPRRGDEGRADEEKNEAGEIIRVRLPQKRNREMFAQAELMMGA
                     NHIRVKCYDGVTRLGRIKGKIKKKIWIREGDILIVIPWSFQDDKCDIIYRYTGPQVEW
                     LRRNGYL"
     gene            1863..2288
                     /locus_tag="PK679_08720"
     CDS             1863..2288
                     /locus_tag="PK679_08720"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC56072.1"
                     /translation="MSRTRSDMSEAAKIIRDLHSPYWSERQSAVRRIAEIGSPEILRD
                     LLQGLRDEKWYIREAASAGIRALDCPDLVPDLVACLENGDEILRNAAALALGNICLPG
                     TASALERVLTDPDCRVRKSARISLERIRSALSRQQPVTP"
     gene            2403..3584
                     /locus_tag="PK679_08725"
     CDS             2403..3584
                     /locus_tag="PK679_08725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HPC56073.1"
                     /translation="MDYRFARRMTCAPPSFLDRLFAVSKDPRIISFAGGLPATRFIDV
                     GGIREAAARVLAEDGRDALQYSTTDGYLPLREYISRRYRQRLGLAIPPEQVQIVNGSQ
                     QCLDLVAKIFLDRGDTVAMERPGYLGAIEAFSLYEPVFRDVALGPCGPDIEEFSRVIR
                     DARPKFFYGIPNSQNPSGQTYSPEARRAVAEVIGDSDTLFYEDDAFGELFFDGKPRPP
                     VAGLVPDQAVLSGSFSKIIAPGMRIGWICAPPPVLGRFNCAKQAADLHSNFLCQKILA
                     AYLETHDLDAHVRRIARAYGENCRLMCEILDDDFPPGLSHTEPEGGMFLMVSLPPGLD
                     SHRLFEEGLRKGVAVLPGTPFYACGGGESTVRLNFSCMEAEQIREGMERLSGVVRALL
                     P"
     gene            3719..4252
                     /locus_tag="PK679_08730"
     CDS             3719..4252
                     /locus_tag="PK679_08730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56074.1"
                     /translation="MADDHRDEGGAGEVPAGKGKEKRHTKSHLYAIAILCIVLIVIAA
                     ALVTLTVQADLPPEPGTTYPYTTTYAVLIPEGKPVSIAGMEIIVLASGDEMLMRIGDR
                     TEKFVVGETKTISERHAVFRTLGIGIFSTNYRIGATYRGKSGGLADFYIVIATSRQVP
                     SFLIERVLPPSIQARAI"
     gene            4626..5210
                     /locus_tag="PK679_08735"
     CDS             4626..5210
                     /locus_tag="PK679_08735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56075.1"
                     /translation="MKAGRTKTPFRALIEGLVGLILVLVALVLIRYVADHTAWPVLDG
                     FAGVLLANAPLIVIFSVLFTIGEVLAAFPFPLNLAFPVFNAVGSMLLVSLILKVIAFL
                     DRFYALGTGSALDIIGFILLPLTLLVTLVAGYMSIFAPSGRPAATAGDRNDSPRTERE
                     GEGSPSWDEIGEEFRKVVNDAVRKIRDEIRQGLT"
     gene            5569..6078
                     /locus_tag="PK679_08740"
     CDS             5569..6078
                     /locus_tag="PK679_08740"
                     /inference="COORDINATES: protein motif:HMM:NF012383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HPC56076.1"
                     /translation="MHSVHPSPSRSHERSGSPGTTESGFGAVTWDGTVLINERLRSAL
                     GLSDHDVRTAVAGTQANVRERVARFLQGRQVPPLEKKTVILTDDGLASGFTMLAVARS
                     VRKRNPAMIVVAVPTASLSAAELVRREVDLVVCLNIRTGRTFAVADAYREWHDMDDAE
                     VLAELAKTS"
     gene            complement(6261..>6862)
                     /locus_tag="PK679_08745"
     CDS             complement(6261..>6862)
                     /locus_tag="PK679_08745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56077.1"
                     /translation="TVTPTPTPTATPTPTPTATPTPTPTYTGHVLTLRPGWNFISVPA
                     TLATGFDTAGVVFAGVDTAGRSLFLYEGATARWTQVQSGDRIRPLEGIWVYSRATTSV
                     PLIYAPAGSGTPPAKALSDGWNSVGIASLQPVQAGDAFRSMQDHWEMAIGYDSLQQRY
                     EPVIIRGNTGTHGDTQVVYPLKGYWIKVNGSCTYTGRIE"
BASE COUNT         1273 a         2163 c         2122 g         1304 t
ORIGIN      
        1 atcaaggcct ggagaatcaa tgtgatcaac ctctgaaacc ccccaccgca actcccatca
       61 cctctcccac ccactcttct ccatggtatt ggaagggtcc ctccggtttg actcggcaga
      121 aggtgccgac gcgtttatca ggtacctgcg gaagaagggc tgcaaggctc ataagaagac
      181 ggtcgccgtt tttttcgagt cggaggagct ggaaggaacc attgacagtt tcatcgcctt
      241 tttgggagac ctcctcggga gggaggacgt ggaagaggac aatggcggga tggacgaaga
      301 ggaggaggga cggaagtgtg acagggccag cgtggaaaac cgcctggaga acctggagaa
      361 ggcgcgggcc cggctggaaa acctcttttc gacctgcgcg gaaggggatg tcgcgttgac
      421 ggaggatgac ctgcacaggc atggcgatga ctttttcgag cacatggccc gggcagtgtt
      481 cccggtcatg cagaggaacc ttgcagagag gggcatcgac ctgccgcccc gggacgagac
      541 ccgcgatgtt tcggacgacc aggtggagga ggccggcgtt ttcctgacgg tgttcgacat
      601 cctcgatgaa aacggcctcc tggagaaaga ccgcgagggg aagtaccggc ttgcccggaa
      661 ggtcccggtg gagcagtgcc ggatgaagat ctcgactttc ggccttggcg atttcgacga
      721 cggggacctg gagccgtacg ggatcgtgcc ctgcacaagc atcgtgatgg actcgcagca
      781 cgaggtggtc atggatggaa cggttgtcac cgagttctcg gccgatgacc tcgatgaggg
      841 gttggcaggc ctcgacgcgg atgcagaaag cctcgatgcc ttcttttcgg atttcgagct
      901 gaagcggctt gccgtcattg ccctcatcga ggtggtgggc gaagccggaa agatcagttt
      961 cgaggacctg cgggaacgcc tcacggaata cgtgctccgg tccgacaagg tggaggcacc
     1021 ggtgaaagtg acgctcgagc aggatttcct ctcctcgctc gttgcagagc tgcgcaaaca
     1081 ggggtatctt gcgggatcgc aggagaacat ccggctggca gggtagccgg gagctctccg
     1141 ccgtcactca cccgcgaaga gaaaaatccg gggataaggg ttatggggag gctggcaggg
     1201 ccggctcctc tcctccccgg cggctgcagg agtaaaatga agagggtgca cggggtgcag
     1261 ggttcccgcc ggggtggacc tcacaggtac ccgttccggc gcagccactc cacctgcggc
     1321 ccggtatacc ggtagatgat gtcgcacttg tcgtcctgga aactccaggg gatgacgatg
     1381 aggatatctc cctcgcggat ccagatcttc ttcttgatct tgcccttgat gcgcccgagg
     1441 cgggtcacac catcgtaaca cttgacccgg atatggtttg cccccatcat cagttcggcc
     1501 tgggcaaaca tctccctgtt ccgtttctgg gggagcctga cacggatgat ctctcctgcc
     1561 tcgttcttct cctcgtcggc cctcccctcg tcgccccgtc ttgggttcag ccaatcaact
     1621 cctcgcggtc caccaagagc cccctttttt gggaatgaac atgtactttt caaggtcgga
     1681 gaatatagaa ttttcccgat cggtctccgc ccggcagttt ttccggggaa ctgcaggagg
     1741 cggatggacc ggatgccact tcaggagccc gggatgacgg gggacaggga ttcgttacag
     1801 gagaaagaag aaggaatgtt ccatccaata ttataaataa cttgttatca tatgtaatca
     1861 ccatgtcccg tacccgcagt gacatgagcg aggcggcaaa gatcatccgc gacctccaca
     1921 gcccttactg gagcgagagg cagtctgccg tgaggcggat cgcggagatc gggagccccg
     1981 aaatcctgcg ggacctcctg cagggtctcc gggatgagaa atggtacatc cgtgaagcgg
     2041 cgtctgcagg catcagggca ctcgactgcc cggacctcgt gccggacctt gtcgcatgcc
     2101 tcgaaaacgg tgacgagatc ctccgcaacg cggcagcact cgccctcggc aacatctgcc
     2161 tgcccgggac tgccagtgcg ctggaacggg tcctcaccga ccccgactgc cgcgtccgga
     2221 agagtgcacg gatctccctg gaacgcatcc ggtctgcact atcccggcag caaccggtga
     2281 ccccctagcc aaaaaccccc ctttttcctg accggcatcc cggttcggct caccggccgg
     2341 ggaggatcac aacgaataag gcattttcca tcaagatgac tctttccccc aaggatgatg
     2401 ccatggacta ccgattcgcc cgccggatga cctgtgcgcc gccctcgttc ctggaccggc
     2461 tctttgccgt ctcgaaagat ccccgcatca tctcctttgc cgggggactg ccggccacgc
     2521 ggttcatcga tgtcgggggg atccgggagg ccgcagcccg tgtccttgca gaggacggga
     2581 gggacgccct ccagtactcg accaccgacg gctacctccc cctccgcgag tacatctcac
     2641 gccggtacag gcagcgcctc gggctcgcga tccccccgga gcaggtacag atcgtcaacg
     2701 gctcgcagca gtgcctcgac ctcgtggcaa agatattcct cgaccgcggg gatacggtcg
     2761 cgatggagcg tcccgggtac ctcggcgcaa tagaggcatt ctccctgtac gaaccggtct
     2821 ttcgcgacgt ggccctcggt ccctgcggac cggatatcga ggagttttcc cgcgtcatcc
     2881 gggacgcccg ccccaagttc ttctacggca tcccgaactc gcagaacccg tcggggcaga
     2941 cctactcccc ggaggcacgg cgcgctgtcg cggaggtgat cggggactcg gacaccctct
     3001 tctacgagga cgacgcgttc ggcgagctct tctttgacgg caaaccccgg cctcccgtcg
     3061 cggggctcgt ccccgaccag gctgtcctct ccggttcgtt ttccaagatc atcgcgcccg
     3121 ggatgcggat cgggtggatc tgtgcaccgc cacccgttct cgggaggttc aactgcgcaa
     3181 agcaggccgc cgacctccac tcgaacttcc tctgccagaa gatccttgcc gcctacctgg
     3241 aaacgcacga cctcgatgcc cacgtccggc gcatcgcccg cgcctacgga gagaactgcc
     3301 gcctgatgtg cgagatcctg gacgacgact tcccgcccgg actctcccac accgagccgg
     3361 aaggcgggat gttcctgatg gtcagcctcc ctcccggcct cgactcgcac cggctctttg
     3421 aggaagggct caggaagggg gttgcagtgc tgccgggaac acccttctac gcgtgcgggg
     3481 gcggggagtc caccgtccgg ctcaacttct catgcatgga ggccgagcag atcagggagg
     3541 gcatggagcg gctttccggg gtcgtcaggg cacttctccc ctgatcgggg caccgggatc
     3601 cccgtcacgg aggggggtta cctgccgggg accacggaca cgtgacagga gaccggggaa
     3661 ccctgcagta cccgcaagct atacgtgcct gcttccccac ctatcctctt gatgcaccat
     3721 ggcagatgac catcgcgacg agggaggggc gggagaagtt cccgccggga aagggaagga
     3781 gaagagacac acaaaaagcc acctttatgc aatagccatt ctctgcattg tccttatcgt
     3841 catcgccgct gcccttgtca ccctcaccgt gcaggcagac ctcccgccgg aacccgggac
     3901 cacctatccc tataccacca cgtacgcggt actcatcccg gagggaaaac cggtctccat
     3961 cgcgggaatg gaaatcatcg tcctcgcctc gggcgacgag atgctgatgc ggatcgggga
     4021 tcggaccgag aagttcgttg tcggggagac caagaccatc tcggagaggc atgccgtgtt
     4081 ccggacgctc gggatcggca tcttctccac gaactaccgg atcggggcaa cctacagggg
     4141 gaagagcggc ggcctcgcag acttctacat tgtcattgca acgtcccggc aggtcccctc
     4201 cttcctcatc gagagggtcc ttccgccttc aatccaggca agggccatct gacccctttt
     4261 tgaaacatcc ccgcaacgca ggacctccct tgtccctgtc ccttccgcgg gcggaatgaa
     4321 tgggggccgt tcctgcacca cggggttctg ccccgcgacc tgcacttccc gggaacggga
     4381 ccagggcggg accttttaaa ggtctcaccc gtgccgggat cgctccggct ggggcaccgg
     4441 cagcaggggg cgatggtgcc ggttccccgg tcatgaatgc gtggtgcacg gggcgcgggg
     4501 agacgggacc gcgaaaccct gcctttccgt tgccattccc ggatgccggg cataaggggt
     4561 cccatccttt atggggtcaa gggttgacct ttccggagat gtctcatgcg tgcaggaggg
     4621 tttccatgaa ggcagggagg acaaaaaccc cgttccgggc cctgatcgag ggtctcgtcg
     4681 gacttatcct cgtcctcgtt gcactcgtcc ttatcaggta cgtcgcggac cacacggcat
     4741 ggccggttct ggacgggttc gccggtgtgc tcctggcaaa cgccccgctc atcgtgatct
     4801 tctcggtgct ttttacgatc ggagaggtcc ttgccgcgtt tccctttccc ctcaacctcg
     4861 cttttcctgt ctttaacgcg gtgggaagca tgctgctcgt ctccctcatc ctgaaggtaa
     4921 tcgcgttcct cgaccgtttc tacgcactcg ggacagggag tgccctggat atcatcgggt
     4981 tcatcctgct ccccctcacc ctccttgtca cgctcgttgc cggatacatg tccatctttg
     5041 cgccgtcggg aagaccggca gcaacggcag gggacaggaa cgattcgccc cgcacagagc
     5101 gcgaaggaga agggtctccc tcgtgggacg agatcgggga agagttccgg aaggtcgtca
     5161 acgacgcggt ccgaaagatc cgggacgaga tccggcaggg actcacatag ggcataccct
     5221 gcccggggag agaccgggca ctctgccccc ctcccggcac tgctccagcc gggtacaatc
     5281 ccggaccgat cgcccgcagg atcgtccccc ctcccttccg gcattttccc gtgcgggaaa
     5341 tgagccgccc ccttttcctc cacatttatg tcccatgagg tccagagcag gaatcaatgg
     5401 gagatctgat cgaggacccg ctgctgcggg acaggacgta cgttttctcc gacaggcacg
     5461 atgcaggcag gaggctggga cgtttcctca cgtcgcttcc ctccatccgg gaccctgtcg
     5521 tccttgccat acctgcgggt ggcgtgcctg ccgggaggct gatcgcagat gcactcggtg
     5581 cacccttctc cctcgcggtc gcacgaaagg tccggatccc cggggacgac cgagtcaggg
     5641 ttcggggccg tgacatggga cgggaccgtc ctcatcaacg aacggctgcg ctcggcactg
     5701 gggctttcgg accacgatgt caggaccgcg gttgcaggga cgcaggcaaa cgtccgcgag
     5761 agggtggccc gtttcctgca ggggaggcag gtccctcccc tggagaaaaa gaccgtgatc
     5821 ctgaccgacg acgggcttgc atcagggttc acgatgcttg ccgtggcacg gagtgtcagg
     5881 aaaaggaacc cggccatgat cgttgtcgcg gtcccgaccg cctccctctc tgctgcagag
     5941 ctcgtccggc gggaggttga cctcgtggtc tgcctcaaca tcaggacggg ccggacattt
     6001 gccgtcgcag atgcctaccg cgagtggcac gacatggacg acgccgaggt tctcgcggaa
     6061 ctggcaaaga catcctgacg gcccgccggt tgcaaaacgg ggcgagtaac ccgctccctg
     6121 cggggtgaaa cggtgagcag gtgcatgcac tctcccctga cgcaggcact ccgcggcatg
     6181 gctcttcttc ccttcccatg gactgcgact gccccgccac ggcggtctcc gcatgaagga
     6241 ttcgattgga aaagtcgctt ctactctatc cggcccgtgt aggtacagct gccgtttacc
     6301 tttatccagt atcccttcag gggatacacg acctgcgtat cgccgtgcgt tccagtgtta
     6361 ccccggataa tgaccggttc gtacctctgc tgcagggaat cgtacccgat cgccatctcc
     6421 cagtggtcct gcatggaccg gaacgcatcc ccggcctgca cgggctggag cgaggctatt
     6481 cccacggagt tccagccatc ggacagcgcc tttgcaggag gggtcccgga tcctgcgggt
     6541 gcatagatga ggggcacaga tgtggtggca cgtgagtaga cccagattcc ctccagcggc
     6601 ctgatcctgt caccggactg cacctgcgtc cacctcgcgg tggcaccctc gtacaggaag
     6661 agggaccggc ctgctgtatc gactcccgca aagacgaccc cggcagtatc gaatcccgtg
     6721 gcaagcgtcg ccggcaccga gatgaagttc cagccgggtc ggagcgtcag gacgtgcccc
     6781 gtgtaggtcg gtgtcggagt aggggttgcc gtcggtgtcg gagtgggagt cgctgtcggt
     6841 gtcggagtag gggtaactgt cg
//
LOCUS       DAOOJU010000049         6251 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_10259_length_6251_cov_15.875565, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000049 DAOOJU010000000
VERSION     DAOOJU010000049.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 6251)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6251)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6251
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10259_length_6251_cov_15.875565"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            322..1422
                     /locus_tag="PK679_08750"
     CDS             322..1422
                     /locus_tag="PK679_08750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018031972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56078.1"
                     /translation="MSAAAAINKIGEQNPISVENCDIKEYYPDVEFVTWDPLLEKETP
                     HYMLLILNSDGKVNMLRAVDECYASKEDKMWMADFLRKMWEKYPAKFAKSDEYTYISI
                     EGKEQGLRLTDEEQKGLEKVDSEITRYLNDLFSADNSPKWSGNEHSMIINDSCWKWGV
                     DSYYRNQATSSAPIPDSFWTFPYNLINHYWNPDPFLSWPGQGRYYCDYYADLGKSNLD
                     LGYNLLAYQQLGYSSHFLTDLGNPLHTGKEAEQLFQGIIPPWSPPLYSWVHNNYEGYV
                     NAYWSIAPPSGPYAFSYFVTNNWYYYQMTDPFVSAQSLAQYSNTKLNTLYYYVYNNPY
                     TLQNDPNTYMITSNVLIDTSKHTLGLVKYVRD"
     gene            1504..2055
                     /locus_tag="PK679_08755"
     CDS             1504..2055
                     /locus_tag="PK679_08755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56079.1"
                     /translation="MTPSEWFLGFIVILLLIGLPSIIFSLLSSLFFIAMNKVRVKLVR
                     LILPPVIFIVIGVILSAAGPGLEMLYKTMGFVAVISWLLFGAIIAMGIITPFPLFERR
                     LPKTKSWIYVFEASIITFFYLFVAEVANQAGLMRVVSRVSPNAYSPIVFLSVLFIEAV
                     VIASLVYGGFTLYYHFSWKLASE"
     gene            2334..2969
                     /locus_tag="PK679_08760"
     CDS             2334..2969
                     /locus_tag="PK679_08760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56080.1"
                     /translation="MKVYGIKTGSFFMLILLFASALISVASAEDEKGVIRSDATAEQL
                     SLINDLYGKDITVLEYMEKVHPEHLVGIPDSYKENMAAHKMTWWAMEPGQNNDTNDDQ
                     LAPDRATVSVSATGYKFDWRTIRFGGTCTASGLEGPPWYIYVEAFLINRGTGQTVDST
                     SASSQQGVWSVTASKDKLYPANGQYYVHAWGYIPTPYYAEDYDDTSVFSFT"
     gene            3047..4237
                     /locus_tag="PK679_08765"
     CDS             3047..4237
                     /locus_tag="PK679_08765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018031950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56081.1"
                     /translation="MVTSAEPVSGTETGLFTLSGEPFHMILDEDRLFWIQDSKYLNAS
                     EQGLFYYNISDGMTKQLGQIGAPAISGDRIVFSEKGIMTINLSTGSTVQLTNQNDAVL
                     PVSDLRFNQNPCIDGDRVVWTEHEGLVHSNVEGGRIVILNLTTGERQYLPTGSPGNQS
                     TPIISGNFILWKDYRHSGPDDQELYLFDLEKGTEERLPTENPVKANPYLSGDEVVWTE
                     EIHGIDMIIHYSISSRTRTVVGQGSVHQGHLPPVSDDRVVWLQSKNPLDIREERNAIM
                     LMDLRTGEKRQITPFRRGLSHPVISGEYIIYTRGAGDDWFNEPREVVLYTLSSSQGET
                     VNGTDTRPGNGNSPTPATNSLDKGEAMPPTSSPGFTCITLIAGCIAALAIKKVRDRIS
                     ICLL"
     gene            complement(5054..5998)
                     /locus_tag="PK679_08770"
     CDS             complement(5054..5998)
                     /locus_tag="PK679_08770"
                     /inference="COORDINATES: protein motif:HMM:NF012692.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HPC56082.1"
                     /translation="MGPVVAVDLGATQTRAAVYESGVRQGEKVGEKTPAGSSDPAVLI
                     SFLSGMVKKASRTSRGKTGAIGLSVAGPVDISRGILRNPPNMAFRDVPLCDALSREFG
                     VPVRMVNDCHAGLVGELEAGAARGRDNVVYVTISTGIGGGVFANGRVLLGRAGNAVEI
                     GHLHVDDTYNLPCGCGHRGHWEGYSSGRFLPWFFAQWCHYHGRPHWGPDNARDIFASA
                     RQGDDDVLRFIRDLVRINARGVSDIIVAYDPEIIVFDGSVMRANPDFLLEPLVGEVDR
                     YLEVPEMVLSPLSGDGPLIGAAVIAEGYATRYGDFGAV"
BASE COUNT         1579 a         1580 c         1593 g         1499 t
ORIGIN      
        1 ggagaatcat caataccgtc acgtgctcta ctccgaatca ttctgctgac agttccggat
       61 ctggcacaga gatcgtttat gcaccttgat ctgattaccc atggagtgtg aggacaagtt
      121 cctcgctcaa gacagctttc cggaaggcag gatgctttcc ctgctgtcat aaatccgggc
      181 tcgaaatcga cgcatcgcac aaagcccgga aggagcgaaa tcgtgatatc agaaagaatt
      241 ggaggaaaca aagatgaaga caatgaaatt tagcatcttc ctgttggaac cccgctgaca
      301 gcgttggtga tagtaccgtc cgtgagcgcg gcggctgcta tcaacaagat aggggaacag
      361 aacccgattt ctgtcgaaaa ttgcgatata aaagaatact atccggatgt ggagttcgtc
      421 acatgggacc ctctccttga aaaggaaacc ccccactaca tgctcctcat cctaaacagc
      481 gatggtaaag tcaatatgct tcgtgcagtt gacgaatgtt atgcctcgaa agaggataaa
      541 atgtggatgg ccgatttcct ccggaaaatg tgggagaaat atcctgcaaa atttgcgaaa
      601 agcgatgagt atacctatat ttccattgaa gggaaagaac agggactcag gttaaccgac
      661 gaggaacaaa aaggacttga aaaagtcgat tctgagataa ctagatatct caatgacctt
      721 ttcagtgccg ataacagtcc gaaatggtca gggaacgagc attcaatgat tataaatgat
      781 tcgtgctgga aatggggagt tgattcgtat taccggaacc aggcaacttc atcagcgcca
      841 ataccggatt ccttctggac atttccatac aatcttataa atcattactg gaatcctgat
      901 cccttcctct catggccggg tcagggaagg tattattgcg actactacgc ggatctggga
      961 aaatcaaacc tcgatcttgg atataatttg ctcgcttatc agcagttggg atattcaagt
     1021 catttcctga ccgatctcgg gaatcctctc cataccggaa aggaggccga acagctattc
     1081 caaggaatca ttcccccctg gtcaccaccc ttgtattcgt gggtacacaa caattatgag
     1141 ggttatgtca atgcgtactg gtccatcgcc ccgccctcgg gcccatatgc attcagttac
     1201 ttcgtaacta acaactggta ctactaccaa atgactgacc ccttcgtatc cgctcaatcg
     1261 ctagcccagt attcaaatac aaaattgaat actctgtatt attacgtcta caacaatccc
     1321 tacacgttgc agaatgatcc aaacacatac atgatcactt ccaatgtttt gatagataca
     1381 tcgaagcata ccctcggact ggtgaaatat gtgcgggatt agactgcaaa ccttttttat
     1441 aaagtacgac cgggatgaaa gatcttgaat atgccatttc catctctagt acggtgagga
     1501 atcgtgaccc cgtcagaatg gttcctggga ttcatcgtaa tcctgcttct tatcggatta
     1561 ccctcgataa tcttctcact cctttcgtct ttgttcttta tagcgatgaa taaagtccgg
     1621 gtgaaactcg tgcgactgat ccttcccccg gttatattta tcgtgatcgg tgtcatcctc
     1681 tcggcggctg gtccgggact ggagatgctg tataaaacaa tgggatttgt cgccgtaata
     1741 agctggttgc tctttggtgc gataatcgcc atgggaatta tcacgccgtt tccccttttc
     1801 gaaaggagat tgcccaaaac aaaatcctgg atttacgttt tcgaagcgtc aataataact
     1861 ttcttttacc tgttcgtcgc agaggtagcg aatcaggcag ggcttatgag ggtagtgtcc
     1921 cgagtctccc cgaatgcata ctctcccata gtattcctgt cggtcctttt catcgaggca
     1981 gtagttattg cctcgctcgt atatggggga tttaccctat attatcattt ttcctggaag
     2041 ctggcttcag agtaggggca cttgcagcga accgaaaaag atgtccctga agtgagggtt
     2101 tgtaaggggt cgtcagtaat gtctcacctt caatgccgtc tgtattatca ttctgctgac
     2161 agttctggat ctggcacaga gatcgtttat gaacctggat ccaattaccc attgggggtg
     2221 aagataaccc cctaaccaca cgacagtcac aaggaacgta taagctgcct ttgctgtcac
     2281 atttccgggc cttcttttgg catttgccag gaggcctgtg aaggaggaga atcatgaaag
     2341 tctatggaat aaaaacggga tcgtttttca tgctgatcct gctgtttgca tctgcactga
     2401 tcagtgtagc gagtgcggaa gacgagaaag gtgtcatcag atcagatgcc actgcagagc
     2461 agttgagcct gattaatgat ctctatggta aggacattac cgtccttgaa tatatggaga
     2521 aggtacatcc ggaacatctt gtcggaattc ctgattcata caaggagaat atggcagctc
     2581 ataagatgac ctggtgggca atggagcctg gacagaacaa cgataccaat gatgaccagc
     2641 tggcccctga tcgggccact gtttctgtca gtgcgactgg gtacaagttt gactggagga
     2701 ccatccgttt tggaggaacc tgtactgcat cgggactgga gggacctccc tggtatatct
     2761 atgtcgaagc gttcctgatt aaccggggaa ccggacagac cgtggattcg acatcggcaa
     2821 gttcacaaca gggggtgtgg tcagtcaccg catcgaaaga taagttatat cctgcgaatg
     2881 gccagtacta tgtccatgca tgggggtata ttcctacgcc ctactatgct gaggactatg
     2941 acgacacttc ggtgttcagt tttacctaat ctttctttca gccatgaata accatcaacg
     3001 ttccagcggc ctcctgataa tcgtcatctg tctggtgacc actcccttgg tcacaagtgc
     3061 agaaccggta tcagggaccg aaacagggct tttcactctt tcgggggagc cattccacat
     3121 gatcctggat gaggatcgac tcttctggat ccaggatagc aaatacctga atgcgtcaga
     3181 acaagggttg ttctattaca atatttccga tggaatgact aaacaactcg gtcagattgg
     3241 agcaccggca atctctggtg atcggattgt gttcagcgaa aaagggatca tgacgataaa
     3301 tctctcgaca gggtctacgg ttcaactcac caaccagaat gatgcggttc tccctgtatc
     3361 cgatctcagg ttcaatcaga atccttgtat tgacggggac cgtgttgtct ggaccgaaca
     3421 cgagggactt gtccactcca acgtggaggg ggggaggatc gtcatcctca acctgaccac
     3481 aggagagagg cagtacctcc cgaccggttc accgggtaac cagagtactc ccataatttc
     3541 aggtaatttc atcctgtgga aagactatcg ccacagtggt ccggacgacc aggaactcta
     3601 cctcttcgat ctggagaaag gaacagaaga gcgtctgcct acggaaaatc cggtgaaggc
     3661 taatccgtat ctctctggag acgaggtggt atggaccgag gagatccacg ggatcgatat
     3721 gattatccat tactccatct catcccggac caggaccgtt gtcgggcagg gaagcgtgca
     3781 ccaggggcat cttcctcccg tctcggacga ccgggttgta tggttacagt caaaaaatcc
     3841 cctggatatc agggaagaaa gaaatgcgat catgctgatg gaccttcgca caggagaaaa
     3901 aaggcagatc actcctttcc gccgtggact ttcccatccg gtcatctcag gggaatatat
     3961 tatatataca cgtggtgcgg gagacgactg gttcaatgaa cctcgcgagg tggtgcttta
     4021 taccctctcg tccagccaag gagagaccgt aaatggtacg gatacccgtc cgggaaacgg
     4081 caactctccg actcctgcaa ccaattcact tgataaaggt gaggcaatgc ctccgacatc
     4141 atcaccgggt tttacctgca tcacactcat tgcggggtgt attgcagcac tggctattaa
     4201 gaaggtcagg gataggattt ccatatgctt gctctaattc caatgaaaat ggcggcgata
     4261 tcatgaaacg gacgcagcgg cccgagcgac tgaagggatc gagtcactga atctcataat
     4321 tatctgttaa acagcgagga gtatggtgcg aggcatgatg cgatgagcgg tatggtacag
     4381 ctgccagcga ggactgtaac gacaatgccg ggagcgtcaa tgaatcagga ttaggtagag
     4441 aaaaccagag acatggcgcg ggtgaaacgg agtcgaggag cacccggcca gagggagaag
     4501 cggatggaga cgaagcgaaa ggagcacgct gccccgctat caaccccggc ccgttgctgt
     4561 gattccctct ctcctgcgat gagattccga tctgatgata aatcacacag ggtaggaatc
     4621 ctttactgca ggagtagagg caccggggtg gaggccccgc acctttcgac ctgtcaggtg
     4681 tgaggtcagg gagaggggtc ggtcgcagag gcgactattt tcgcggtaaa aaaaggatag
     4741 tacgggactg tctgtccttg tcccatctgc agcacttctt tggtctcctt ttgattttat
     4801 tagagaagca gggtaatatt tcaccccgtt tttcttatct aaaactgtcc cgcatatcct
     4861 atactgggca cattttcatc tcaatgtgaa atgattcctg cagcactacc tttcaattat
     4921 gaaaaagtct ccgccctttt catcctgcag attttatccc gaagagaaac acgtggtttt
     4981 tttccaaggt cttttctata acgcaaggtt ttgggaaaaa gggaaaattc cactatcgcg
     5041 ggataaataa ccgttacacc gccccgaagt ccccataccg tgttgcgtat ccctctgcaa
     5101 tgacggccgc ccctatcagg ggaccatcac cggacagcgg ggacagcacc atctcgggca
     5161 cctcgaggta ccggtccacc tctcccacca ggggttcgag caggaagtca gggtttgcac
     5221 gcatgacgga cccgtcaaag acgattatct cgggatcgta ggcaacgatg atgtcagaga
     5281 ctccgcgggc attgatacgg acgaggtccc tgatgaaccg gagcacgtcg tcgtccccct
     5341 gccttgcaga ggcaaatatg tcccgtgcat tatccggacc ccagtgcggc ctcccgtggt
     5401 agtgacacca ctgggcaaag aaccagggga ggaacctgcc ggaggaatac ccttcccagt
     5461 gtccccggtg accgcacccg caggggagat tataggtatc gtccacgtgc aggtggccga
     5521 tctcgacggc gtttcccgcc cggccgagga gaaccctgcc gttcgcgaac acgccacccc
     5581 cgatgccggt cgagatggtg acgtagacca cgttatccct cccgcgtgct gcaccagcct
     5641 cgagctcccc gacgagaccg gcgtggcagt cattgaccat ccggaccggg accccgaact
     5701 cccgggagag ggcatcgcac agggggacgt ccctgaatgc catgttggga gggttcctga
     5761 gaatgccgcg ggatatgtcc accggcccgg caaccgaaag gccgattgca ccggttttcc
     5821 cgcgggaggt acgggatgct ttcttcacca taccggagag gaacgatatc aaaaccgccg
     5881 gatcggatga acccgccggc gtcttctccc cgaccttttc tccctgccgg acaccgcttt
     5941 cgtacaccgc tgcccgcgtc tgcgtcgccc cgaggtcaac tgcaaccact ggacccatgg
     6001 atccggtgtt ttttcccggg gctgatgaag gtatgccggt tttgttgtcc ctgccgggaa
     6061 taaccctcct cccgggggaa ggcccggtga ctataagggg gagaccaacc cttttgatag
     6121 agagaaatac cgggaaggtt agcccattgt ccgcatccgg catgacacac agcctgatag
     6181 gcgattacct gacgctcttt gcagcgacgg agatcttcat cttcgttttc atggagatcg
     6241 tcacgaaagt c
//
LOCUS       DAOOJU010000050         6072 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_10613_length_6072_cov_16.223533, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000050 DAOOJU010000000
VERSION     DAOOJU010000050.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 6072)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6072)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6072
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10613_length_6072_cov_16.223533"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            262..747
                     /locus_tag="PK679_08775"
     CDS             262..747
                     /locus_tag="PK679_08775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56083.1"
                     /translation="MKPPRVPPMLSALVQSGVLAVDGHVFSRLDACPRCGGKVSGYDT
                     RERRFAVIVDGGEKRPVNVLVRRYMCTDCGQVSPAEAPFYPDTRLGSPIVDLCVVLSR
                     NMTPGRASRVAECLSLAIDPGTIRAYSRRAFPEIPVDTLFGIPVPRSLLSLSLMATER
                     Q"
     gene            complement(725..946)
                     /locus_tag="PK679_08780"
     CDS             complement(725..946)
                     /locus_tag="PK679_08780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56084.1"
                     /translation="MSVLLLAGSLLATVILWLWGFPFFFLFLFIPLIPQVWKERKVRS
                     CPVCGFSTTDGKVAFCPYDGTPLTDVQSP"
     gene            complement(943..1878)
                     /locus_tag="PK679_08785"
     CDS             complement(943..1878)
                     /locus_tag="PK679_08785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HPC56085.1"
                     /translation="MIGIDVGGANVKVATDSGVHTLYCPLWKGVPLRDILSRYRDEGK
                     EGAAVVMSGELADCFSSKDEGIAWIVRTVRDVFPGALFYGTDGRFHDSPAPALAAANW
                     FAAAVYLHSLYPGGLLVDMGSTTTDIVPLSSPGSLRGLTDLARLQKGYLLYTGLLRTP
                     VPAVIRNVPIHGIQTPVSSEYFATSADAHLVLGHICAEEYTCDTPDGQGKDRDSCLRR
                     LARVVCADLSEIGEQGAIAIAAAFWETQREMVRAAVLKVQQVSGADPVIAAGTGSRLL
                     VPLLGARDLACDIGDAASALPAHAVREVMRRDLTW"
     gene            complement(1875..2762)
                     /locus_tag="PK679_08790"
     CDS             complement(1875..2762)
                     /locus_tag="PK679_08790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HPC56086.1"
                     /translation="MKALLAEYATFHDPRLAPEGRVMLDVLSRSFARCGYEVVTPDGS
                     DFPGEIRRLAPGCDVGLVIAPDHLLFRYTSVLERLTHNVGCGSMNAAICADKAQCGRI
                     LARHGIPVPGEPQPGKQVIKPVAGCGSVNVRLSDEPPGPGEIAQEFIDGENLSVSLVG
                     SRVVGDACSYYTGKPPLLLAVNRQDVQVSPSGEFHYRGGETPVDHPRHDEIVETAVRA
                     VQVLGCQGYVGIDIVLADRPYVVDVNPRVTTSIVGIAACMEEEIADILVQASRGGGPE
                     SVHMRRRARFDSHGTVEFL"
     gene            2844..3647
                     /gene="surE"
                     /locus_tag="PK679_08795"
     CDS             2844..3647
                     /gene="surE"
                     /locus_tag="PK679_08795"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HPC56087.1"
                     /translation="MKPRILLTNDDGINSAGLWAAYEALSPISEVTVVAPATQQSAVG
                     RSISIFEPIRAHEVEMNGVTAYAVGGKPTDAVIIGLYALGIRPAMVVSGINIGENLSF
                     ESIMTSGTVGAALEAANQGTRAIAFSLQVEDQGDKFDDPRRHRQSFEPSKRVVQEVCR
                     TFLERPFPRGVDVLNVNIPSVIKGGYEVTRLAEKLFATGVEKRLDPRGRPYFWINGPL
                     ISDAGEGTDVHAIRKGNISLTPITLDCTATGAREELSRLFSTAKEGEGR"
     gene            3644..4342
                     /gene="rpiA"
                     /locus_tag="PK679_08800"
     CDS             3644..4342
                     /gene="rpiA"
                     /locus_tag="PK679_08800"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HPC56088.1"
                     /translation="MNAAEREKAKRNAGMKAAEFVRDGMIIGLGTGSTTYHFMVRLAE
                     RIKAEEISVTGIPTSLQTAIRARELGIPLATLDDHPDPDLAVDGADQADRDLRLIKGR
                     GAALTREKVVAAAAARLVIVADEEKYTERLAGTVPVEVIPFAARPVMLAVPELGGEPA
                     IREGKAKDGPVITDNGNYIIDCTFPTIPDPAGLEEELTLIPGVLECGLFCRYTQKTIL
                     VAGNAAGTRIIGKN"
     gene            complement(4345..4719)
                     /locus_tag="PK679_08805"
     CDS             complement(4345..4719)
                     /locus_tag="PK679_08805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC56089.1"
                     /translation="MKSRNVMYFTPREEEMADLLVQIGLKKNVAKVLIYLAHTHEATS
                     RDIERGTDLRQPEVSIAMASLIDQKWVENRETKAENKGRPVKIYRLSRPIHEIMDSIE
                     QQKKEEAENQLMLIRQVREYIS"
     gene            complement(4811..5371)
                     /locus_tag="PK679_08810"
     CDS             complement(4811..5371)
                     /locus_tag="PK679_08810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TATA-box-binding protein"
                     /protein_id="HPC56090.1"
                     /translation="MKVKPEDSLKIENIVASAKVTDYLDLPALASQIKDAEYNKKRFP
                     GVVIRMQQPKIAALVFGSGKVVLTGAKSIESLSQGLEILGNLLRGLNIDIPKKLTYKI
                     QNIVTSADLGSGINLNKIAVGFNLDRIEYEPEQFPGLVYRLENPKVVVLLFGSGKLII
                     TGGKEPEDARKAVQKILTDLKNLGLL"
     gene            5579..>6072
                     /locus_tag="PK679_08815"
     CDS             5579..>6072
                     /locus_tag="PK679_08815"
                     /inference="COORDINATES: protein motif:HMM:NF019407.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin N-terminal domain-containing
                     protein"
                     /protein_id="HPC56091.1"
                     /translation="MPRQNREGGINEVIGTILMVVLIIALAVIIGGIVMGYIVIQPKS
                     AYIPPRIEVVDYAGSRAISLYSRGGDPAALDPAEESRYVLEIFLDTDRGTFKVVPDGD
                     VKTWNPGETIYIYYNNTAAEYRAGNEVPEYLPDSIPDANILLRVVDKRAQLLVLKEGV
                     AVGGG"
BASE COUNT         1253 a         1774 c         1853 g         1192 t
ORIGIN      
        1 cgaggttgaa ggaacacccc gtcccgcaat agggacaggt tgtctgtacg tacttgacgt
       61 ccattggaaa acctcgaaca gaacaatgtc tccagtgaac cctatttaac gatgctgttt
      121 taaaacgaaa aatcgatgaa tactggtggg taaattcccg tcacggatgg tatccgggcc
      181 agggaaaacc ttgtcgctgc acgaggatca gaaaatgaga ggtattttcg tcgaaagggg
      241 cgcagggaag gggatgcgcc cgtgaagccg ccgcgggtgc cccccatgct ttcagccctc
      301 gtccagtcgg gggtccttgc cgtggacggc cacgtctttt cccgccttga tgcatgcccc
      361 cgctgcgggg gaaaggtatc ggggtacgat accagggaga ggcgctttgc tgtcatcgtg
      421 gacggcgggg agaagaggcc ggtgaacgtg ctcgtccgga ggtacatgtg cacggactgc
      481 gggcaggtct ccccggcaga ggcaccgttc tacccggata cgcgccttgg gtcacccatc
      541 gtggacctct gcgtcgtcct ctcgcggaac atgacgccgg ggcgggcatc acgggttgca
      601 gaatgcctct cccttgccat cgacccgggc acgatccgtg cctattcgcg ccgggcattc
      661 ccggagatcc cggtcgacac cctttttggt atcccggtcc cgcggtccct cctttccctc
      721 tccctcatgg cgactgaacg tcagtaaggg gtgtcccgtc gtacgggcag aatgcgactt
      781 tcccgtccgt cgttgaaaaa ccgcagacgg gacaggaacg caccttcctc tccttccaga
      841 cctgcgggat gagcgggatg aagaggaaga ggaagaagaa cgggaaaccc caaagccaga
      901 ggatgacagt ggcaaggagc gagcccgcga ggagcaggac gctcaccacg taaggtctcg
      961 tctcatcacc tcccggacag catgggcagg cagggcggat gcagcgtcac cgatgtcgca
     1021 tgcgagatcc cgggcaccca gcaggggaac gaggagccgg gaacccgtgc ctgccgcaat
     1081 gacgggatcc gccccggata cctgctgcac cttcaggacg gcggctctta ccatctcccg
     1141 ctgtgtctcc cagaacgcgg ctgctatggc aatggctccc tgctccccta tttccgacag
     1201 gtccgcacac acaacccgtg cgagccgccg gaggcaggaa tcccggtcct ttccctgtcc
     1261 gtccggtgta tcgcaggtat actcttccgc gcagatatgg ccaaggacga ggtgggcatc
     1321 cgcgctcgtc gcgaagtact cggaactgac gggcgtttga atgccatgga tcgggacgtt
     1381 cctgatgact gccgggaccg gggtccggag gagccccgtg tagaggaggt accccttctg
     1441 gagccgggcg aggtcggtga gaccccggag gcttccggga gaagagaggg gaacgatgtc
     1501 ggttgtggtg ctccccatgt cgaccaggag accgccgggg tagagagaat ggaggtatac
     1561 ggcggctgca aaccagtttg cggctgcaag cgcaggcgcg ggagagtcat ggaacctgcc
     1621 atcggttcca tagaagaggg ccccgggaaa cacgtccctg acagtccgga cgatccatgc
     1681 aataccctcg tccttgctgg agaaacagtc ggcaagttcc ccgctcatga cgacggcagc
     1741 cccttctttt ccctcgtccc tgtagcggga gaggatgtcc cggagcggaa cacccttcca
     1801 gagcggacag tacagggtgt ggaccccgga atccgtcgca accttgacgt tagctccccc
     1861 cacgtcgatg ccaatcacag gaactccacc gtcccatggc tgtcaaaccg ggcccgccgc
     1921 ctcatgtgga ccgactccgg gcccccgccc ctcgatgcct ggacaaggat atcggcaatc
     1981 tcctcctcca tgcatgcggc aatcccgacg atgctcgtcg tcacccgcgg gttgacgtcc
     2041 accacgtagg gcctgtccgc aaggacgata tcgatcccca cgtacccctg gcaccccagt
     2101 acctggacag cccggacagc cgtctccacg atctcatcgt gccgggggtg gtcaacgggg
     2161 gtctccccgc ccctgtagtg gaactctccg gagggactga cctgcacgtc ctgcctgttc
     2221 acggcaagga ggaggggtgg tttcccggtg tagtaggaac atgcatcgcc gacgaccctg
     2281 ctcccgacca ggctcacgct caggttctcc ccgtcgatga actcctgggc gatctcgccc
     2341 gggcccggcg gctcatcgga gagccggaca ttgaccgacc cgcatcctgc aacgggtttg
     2401 atgacctgtt tgccgggttg cggttctccc ggcacgggga tgccatggcg cgccaggata
     2461 cggccgcact gggccttgtc ggcgcagatt gcggcattca tgctcccgca gccgacatta
     2521 tgcgtgagac gttccagcac ggaggtgtac cggaagagga ggtggtcagg agcgataacg
     2581 agcccgacgt cgcatccggg ggcgaggcgg cggatctcgc cggggaaatc gctgccatcc
     2641 ggtgtgacca cctcgtaccc gcaccgcgcg aaactccggg agaggacatc cagcatcacg
     2701 cgtccctcgg gggcaaggcg gggatcgtgg aacgttgcat actcggcgag gagcgctttc
     2761 atgccgggta catgcgtttc ccattcagat aggcatgacg atcgatcaac tatttctccc
     2821 cttcctccca atgggatggt gacatgaaac cccgaatcct cctcaccaac gatgacggga
     2881 tcaattctgc cggtctctgg gctgcctacg aggccctctc gcccatctcg gaagtgaccg
     2941 tcgtggcacc ggcaacccag cagagtgccg tggggcgatc gatctccatc ttcgagccga
     3001 tccgggccca cgaggtggag atgaacggtg tcactgccta tgccgtcggg ggaaagccga
     3061 ccgatgccgt catcatcggg ctctatgccc tcggtatccg ccccgcgatg gtggtgagcg
     3121 ggattaacat cggggagaat ctctcgtttg agtccatcat gacatccggg accgtgggtg
     3181 cagcactcga ggcggcaaac caggggaccc gggcaatcgc attctccctc caggtggaag
     3241 accagggcga caagttcgac gacccgcgga ggcacaggca gagtttcgag ccctcaaaga
     3301 gggtggttca ggaggtatgc cggacattcc tcgaaagacc ttttccccgc ggggtcgacg
     3361 tcctgaatgt caacatcccc tcggtcataa aaggcggata cgaggttacc cgcctcgcgg
     3421 agaagctctt cgccacgggc gtggaaaaga ggcttgaccc ccgggggagg ccgtacttct
     3481 ggatcaacgg acccctcatc tccgatgccg gcgagggaac ggatgtgcat gccatccgga
     3541 agggaaacat ttccctcacc ccgattacgc tcgactgcac ggcgaccggg gcacgggaag
     3601 aactttcccg gcttttttcc actgcgaagg agggggaggg gagatgaacg cggcagagag
     3661 ggagaaggca aagaggaatg ccgggatgaa ggctgcagag ttcgtccggg acggtatgat
     3721 aatcggactc gggacaggct cgacgacgta ccatttcatg gtccggcttg cggaaagaat
     3781 aaaggccgaa gagatatccg tgaccgggat ccccacatcc ctccagacag ccatccgtgc
     3841 ccgcgagctt ggcatcccgc tggcaacgct cgatgaccat cccgatccgg acctcgccgt
     3901 ggatggagcg gaccaggcag acagggacct tcgcctgatc aaggggcggg gggcagccct
     3961 cacacgcgaa aaggttgttg cagccgcggc ggcacgtctc gtcatcgttg cggacgagga
     4021 gaagtacacc gaacggctcg ccggtacggt gccggtcgag gtcatcccgt ttgctgcacg
     4081 gcccgtgatg cttgcagtcc ctgaacttgg cggagaaccg gcaatccggg aaggaaaggc
     4141 aaaggacggg ccggtcatca ccgacaacgg caactatatc atcgattgca cgttcccgac
     4201 aatacccgac cctgcaggcc tcgaagaaga gctgaccctg attcccgggg ttctcgagtg
     4261 cggcctgttc tgccgctata cacaaaagac gatccttgtt gcagggaatg cggcggggac
     4321 gagaattatt gggaagaact gaattcagga gatgtattcg cggacctgcc tgatgagcat
     4381 gagctggttt tccgcctctt ccttcttttg ctgctcgatg ctgtccatga tctcgtggat
     4441 tggacgcgag agcctgtaga tcttgacggg ccttcccttg ttctcggcct tcgtctccct
     4501 gttctcgacc catttctggt cgatgaggga ggccatggcg atgctgacct cgggctgccg
     4561 gaggtccgtt cccctctcga tatcccggga agtcgcctcg tgcgtgtggg caaggtaaat
     4621 caggaccttt gcaacgttct tcttgagacc tatctgcacg aggaggtcag ccatttcctc
     4681 ttcccggggt gtgaaataca tgacatttct cgatttcatg ggcgcaccgt cgctcctacg
     4741 atataggtaa caattacata aaaagattat tattatttat aaactcataa taagtaataa
     4801 ataaaaggat ctataagaga ccgaggttct tgaggtccgt gaggatcttc tgaacagcct
     4861 ttcgggcatc ctcgggctcc ttgcccccgg tgatgatgag ttttcccgac ccgaacagga
     4921 ggacgacaac tttggggttc tccagcctgt agacgaggcc ggggaactgt tccggttcgt
     4981 actcgatccg gtcgaggttg aaaccaacag cgatcttgtt gaggtttatc cccgatccga
     5041 ggtccgctga cgtgacgata ttctggatct tgtaggtcag ttttttgggg atatcgatgt
     5101 tgaggccccg caggaggttg cccaaaatct cgaggccctg cgagaggctc tcgatactct
     5161 ttgcaccggt caggacaacc ttgccggaac caaagacgag ggcagcaatc ttcggctgct
     5221 gcatcctgat gacaacgccc gggaaccttt tcttattgta ttcggcatct tttatctgtg
     5281 aggccagggc ggggagatcc aggtaatctg tcacctttgc agaggcaacg atgttttcaa
     5341 tcttgagaga gtcctctggc ttaaccttca tatttataaa tgaatccggg cagtatataa
     5401 acagttgggt tggcggatgg ctgcggttac cggttcctga ctttctcacc ggctggagca
     5461 tgacccttga gccgcggaca tcgccggaat ccggacaccg gcaggaattg gcgtccgttc
     5521 actcgtccct tcacgaagag agatatattg ataatcacac acaggagggt atattcatat
     5581 gccacggcag aaccgggaag gcggtatcaa cgaggtgata ggcacaatcc tgatggtcgt
     5641 gctcatcatc gcgcttgcag tcattatcgg ggggatagtg atgggctaca tcgtgatcca
     5701 gcccaagtca gcgtatattc caccccggat cgaggtcgtg gattatgcgg gcagcagggc
     5761 gatcagcctc tactcgcggg gaggtgatcc ggctgccctt gacccggcag aggagagccg
     5821 gtacgtcctc gagatattcc tcgacaccga caggggcaca ttcaaggtcg ttcccgatgg
     5881 agatgtgaag acgtggaacc ccggcgagac catttacatt tactacaaca acacggcagc
     5941 cgaataccgg gcaggcaacg aagtcccgga gtacctgcct gattcgattc cggatgcaaa
     6001 tatcctgctc cgggtcgttg acaagagagc gcaactcctc gtgttgaagg aaggggttgc
     6061 ggtgggtgga gg
//
LOCUS       DAOOJU010000051         5919 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_10932_length_5919_cov_16.339870, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000051 DAOOJU010000000
VERSION     DAOOJU010000051.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5919)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5919)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5919
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10932_length_5919_cov_16.339870"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1445
                     /locus_tag="PK679_08820"
     CDS             <1..1445
                     /locus_tag="PK679_08820"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HPC56092.1"
                     /translation="MDENFRTTYVNPRMASLLGYAPEEMLGREITSFMPESEREDNLE
                     KIRDRMAGKPGEYERRFLHRDGSVRIMRVSATPVFDDNGTFRGSLTMLTDITEKKRIE
                     DEFHREHLELSAAYQQITATDEELRRMLEELREYQETLAESERRYRRIISGTFDAMVI
                     HREGKIIWANEKALEIIGASRMQDIVGRNVLDFVHPGSRQEVIGRMARMVQDQSVVMP
                     LIEEKFLRLDGSPVDVEVTATSTVEDGKPATIVAFRDITDRKRMQEALMTANRKLHIL
                     NSITRHDIQNKVTVLSGYLTLLRDHQKGRDMEKCLDSLENTLHAIQQIIDFTRTYQDL
                     GVRSPEWQAVSDVAGRVMGQFELEGIAVDLLDCSCEVFADPMLEKVFYNLIDNALRYG
                     GGISGIRISCTKEDGDLVIAFEDDGVGIPDDQKEHIFEQGYGKGTGLGLFLSREILSI
                     TGIGIRECGTPGSGARFEIRVPQGLWRENL"
     gene            1759..2928
                     /locus_tag="PK679_08825"
     CDS             1759..2928
                     /locus_tag="PK679_08825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HPC56093.1"
                     /translation="MKKQAVFIFGIFLVAGLVFLAGCTGTPGQEEKKAPETTAAAKTL
                     TLTDGFSRQVTIPFPPQKVVCSGSGCLRYLVYLGGQDLVAGVDDIEKKEQTIEGRPYA
                     LAYGQKFRDLPLIGEFRGKDDPEKIIAIAPDVIFKTGSSGTAYATSAADADKLQEKTG
                     IPVVAFPYGSLRNEAEKAEMFGALRIMGKATGREARAEEIIAYIEATMADLDNRTAGI
                     PESDQKKVYIGGVSSAGAHGIISTEPAYPPFLWVHAQNVAAGMGTAHADIAKEALVAW
                     DPEYIFIDVGTLQLDNEGAVGELKNDPALQGLSAVREGRIYGVLPYNFYNTNYETVLA
                     NAYFVGKVLYPDRFADIDPAKKADEIYTFFIGKPVFSTLNSQYGNRGFARISLSE"
     gene            2969..4039
                     /locus_tag="PK679_08830"
     CDS             2969..4039
                     /locus_tag="PK679_08830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HPC56094.1"
                     /translation="MHFADGEVPGDYVGYVHKKVLWLTGGFFFLLVLLVYSVSVGAVA
                     IPVSDVFLTLFGQNVSHQYDAIIWNIRLPQALTAVAAGCGLAVAGVAMQSILRNPLGS
                     PFTLGISNAGAFGAAFSVIVLGTGTMQSRVADAITINNPYVTTIMAFLFCLLATAVIL
                     LISRVRGASPEVMVLAGVALSSLFTAGTMFLQYFSSDAQLAAVVFWTFGDVGRANWPE
                     LGFMSLIVAAATVYFVANRWNYNAIDAGDETAKGLGVNVGRVRLAGMVAAALVSAVIV
                     AFLGVIGFVGLVCPHMVRRVIGDDQRYLIPGSCLMGGILLLASDTVARVIVAPYVLPV
                     AVLTAFMGAPVFIYLLLRGYRR"
     gene            4036..4812
                     /locus_tag="PK679_08835"
     CDS             4036..4812
                     /locus_tag="PK679_08835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HPC56095.1"
                     /translation="MTLSVQDLSFFYRNREVLNEIAFSIGKCEIVAILGPNGVGKTTL
                     LKCLNRILQPREGVVYLDGKDLFRLDGSEIARNIGYVPQRIETGRLTAFDAVLLGRKP
                     HIGWDISENDLRMVDAVFRRLAMEHLRLAYIDEMSGGELQKVAIARALVQEPRILLLD
                     EPTSNLDLKNQVAILSTIARIVREHGISAVMTMHDLNHAIRYADRFIFLRNGRIHAHG
                     GPETITPKTIEEVYGLPVIIGKLGGVTCIVPESSPVSTGA"
     gene            4843..5484
                     /locus_tag="PK679_08840"
     CDS             4843..5484
                     /locus_tag="PK679_08840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HPC56096.1"
                     /translation="MCENHEGARHGPAYPAFDECVRFHGHSCPGLATGYRVAIAAMKA
                     LSVNRPFDEELVCVAETDACGVDAVQVVTGCTAGKGNLVIRDWGKHAFSFFSRDSGKA
                     VRVLVKNSHMPGRSAMDDLRRKVFSGTATPEETARFHAMMAETTRSLLSVPESDLLEI
                     RELAEKPPEKARIFASVVCEACGEPVADARTRVVRGRRVCIPCSLAGESPERP"
     gene            5481..5897
                     /gene="tsaA"
                     /locus_tag="PK679_08845"
     CDS             5481..5897
                     /gene="tsaA"
                     /locus_tag="PK679_08845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HPC56097.1"
                     /translation="MTPAPLELVPIGYVRSPFRGRKDAPRQGRLAPVVSEIVVRPEFE
                     DGLFRLDEKTHLFVLCWFDRADRTKLRAIPPHDPVERGVFATRSPDRPNPVSLTLVDL
                     VSIDGRVLSVRGLDALDGTPVIDIKPYSEDIDRPHE"
BASE COUNT         1199 a         1837 c         1774 g         1109 t
ORIGIN      
        1 agatggacga gaacttccgg acgacctacg tcaacccccg gatggcatcg ctcctcgggt
       61 acgcccccga agagatgctg ggccgcgaga tcacctcttt tatgccggag agcgagcgag
      121 aggacaacct cgagaaaatc agggaccgga tggcgggaaa acccggggaa tacgagcgca
      181 ggttcctcca cagggacggg tcggtccgca tcatgcgtgt ctcggcgaca ccggtctttg
      241 acgataacgg cacgttcagg ggctcgttga cgatgctcac cgacatcacc gagaaaaagc
      301 gcatcgagga cgagttccac agggagcacc tggaactctc cgctgcatac cagcagatca
      361 cggcaacaga cgaggaactg cgcaggatgc tcgaggaact ccgggagtac caggagaccc
      421 tcgcggagag cgaacggcgg taccggcgga tcatatcggg caccttcgat gcgatggtca
      481 tccaccggga aggaaagatc atttgggcga acgaaaaggc ccttgagatc atcggtgcat
      541 cacgcatgca ggatatcgtc gggaggaacg tgcttgactt cgtccacccc ggctcgcggc
      601 aggaagtcat cgggaggatg gcccggatgg tgcaggatca gagtgttgtc atgccgctca
      661 tcgaggaaaa attcctcagg ctggacgggt ctcccgtcga cgtcgaggtg actgcaacct
      721 ccaccgtaga ggatggaaaa cctgccacga tcgtcgcgtt ccgggacatt actgaccgga
      781 aacggatgca ggaagccctc atgaccgcga acaggaaact gcacatcctc aacagcataa
      841 cccggcacga catccagaac aaggtcactg tcctctccgg ttacctcacc ctcctcaggg
      901 atcatcagaa aggaagagac atggaaaaat gcctcgactc gctcgaaaac accctgcacg
      961 ccatccagca gatcatcgac ttcacgcgga cataccagga ccttggcgtc cgttccccgg
     1021 agtggcaggc cgtttccgac gtggccggga gggtcatggg ccagttcgaa ctggagggga
     1081 ttgccgtgga tctgctggac tgttcctgcg aggtctttgc agacccgatg ctcgagaagg
     1141 tcttctacaa cctcatcgac aatgccctcc ggtacggcgg tggcatatcc gggatccgga
     1201 tctcctgcac gaaggaggat ggcgatctcg tcatcgcgtt cgaggatgac ggcgtcggca
     1261 tcccggatga ccaaaaggag cacatattcg agcaggggta cggcaagggg accggccttg
     1321 gcctcttcct ctcccgcgag atcctctcga tcaccgggat cggcatccgg gagtgcggga
     1381 cgccggggag cggggcccgg ttcgagatca gggtcccgca gggcctgtgg cgggaaaacc
     1441 tgtagggacg aagaaaaaag ggcggcccgt tttttcctgc acctgcccga aacaggggca
     1501 gggattgatc gtgcccccga ccagttccgg gttcgttttt cgaagggcga aaaaccgaag
     1561 cgtccatctt ttgaatcctt ttccgggttt tcggaaccct ggtggtcccc ctttatcttt
     1621 ttaaaaaaaa ttccattaat ttttcataaa tttgggcatt atatcattaa tatatttaat
     1681 attttaaata aaattcacat atcacttgtt tttacaattt aggtatattg aaataataag
     1741 atcattgaac acattaatat gaaaaaacag gccgtgttca ttttcggtat tttccttgtt
     1801 gccgggctcg tattccttgc aggatgcacg ggcaccccgg gacaggagga aaagaaagcc
     1861 ccggagacta ccgctgcggc aaagaccctc acgcttacgg acggattctc ccggcaggtc
     1921 acgatcccct tcccgccgca aaaggtcgtc tgttccggct cgggctgcct ccgctacctc
     1981 gtgtacctcg gggggcagga tctcgttgcc ggcgtcgatg acatcgagaa gaaggaacaa
     2041 acaatcgagg ggaggcccta tgcccttgca tacgggcaga agttccgtga cctccccctg
     2101 atcggcgagt tcaggggcaa ggacgatccc gagaagatca tcgcgatcgc cccggacgtc
     2161 atcttcaaga ccgggtcgtc cggtacggcc tacgcgacga gtgcggcaga tgccgacaag
     2221 ctccaggaaa agaccggtat tccggtcgtt gcattcccgt acggctctct ccggaacgag
     2281 gccgagaagg ccgagatgtt cggcgcactc cggattatgg ggaaggccac cggcagggaa
     2341 gcgagggccg aggaaatcat tgcctacatc gaggcgacga tggctgacct cgacaaccgg
     2401 acggcaggca tccccgaatc cgaccaaaag aaggtctaca tcggcggcgt gagttctgca
     2461 ggtgcccacg gaatcatctc caccgaaccg gcttacccgc cgttcctctg ggtgcacgca
     2521 cagaacgtgg cagcgggcat ggggacggcc cacgcggata tcgccaagga agcccttgtc
     2581 gcgtgggacc ctgaatacat cttcatcgac gtgggcacgc tgcaactgga caacgagggg
     2641 gcagtgggcg agttaaagaa cgaccccgcc ctccagggac tatccgccgt cagggagggc
     2701 aggatctacg gggtgctccc gtacaacttc tacaacacga actacgagac cgtgcttgcc
     2761 aatgcctact tcgtcggcaa agtcctctac cccgaccggt tcgcagacat cgaccccgcg
     2821 aagaaagccg acgagatcta cacgttcttc atcgggaaac cggtcttctc cacgttgaac
     2881 agccagtacg ggaaccgggg atttgcaagg atttcgcttt cggagtgata cggacaggca
     2941 cacgcagtgc agcgggggat caggacacat gcactttgcc gatggggaag tcccggggga
     3001 ctacgtgggc tacgtccaca aaaaggtcct ctggctgacc ggaggattct tcttcctcct
     3061 cgtcctcctc gtttactccg tctcggtcgg ggcagtggca atcccggtct ccgacgtttt
     3121 cctgaccctc ttcgggcaga acgtctcgca ccagtacgac gcgatcatct ggaacatccg
     3181 cctcccgcag gccctgacgg cggttgctgc cggctgcggc cttgccgttg ccggggttgc
     3241 catgcagtca atcctccgca acccgctcgg gtcgccgttc accctcggga tatcgaacgc
     3301 cggggctttc ggggcagcgt tttccgtcat cgtgctcggg accgggacga tgcagtcccg
     3361 ggtcgcggac gccatcacca tcaacaaccc gtacgtcacc acgatcatgg cattcctctt
     3421 ctgcctgctc gcgaccgctg tcatcctcct catctcgagg gtccgcgggg cttccccgga
     3481 agtcatggtc ctcgcgggag tcgccctctc gtctctcttt acggccggga cgatgttcct
     3541 ccagtacttc tcgagcgatg cccagctcgc tgcggtcgtc ttctggacgt tcggggacgt
     3601 cgggcgtgcg aactggcccg aactggggtt catgtccctc atcgtcgcgg ctgcaaccgt
     3661 ctacttcgtg gccaaccggt ggaactacaa cgccatcgat gccggtgacg agacggcaaa
     3721 aggcctcggc gtgaacgtcg ggcgtgtccg ccttgccggg atggtcgcag cagccctcgt
     3781 ctctgccgtg atcgtcgctt ttctgggcgt gatcgggttc gtgggactcg tctgccccca
     3841 catggtcagg cgggtcatcg gggacgacca gaggtacctg atccccggtt cctgtctcat
     3901 gggcgggatc ctcctgctcg cttccgacac cgtcgcccgg gtgatcgtcg ctccctacgt
     3961 cctcccggtc gccgtcctga cggcgttcat gggagcgccg gtattcatct accttctcct
     4021 cagggggtac agaagatgac tctttcagtc caggaccttt cgttcttcta ccggaaccgg
     4081 gaagtgctca acgagatcgc gttctcgatc gggaaatgcg agatcgtagc gatcctcggt
     4141 cccaacggcg tgggaaagac cacgctcctc aaatgcctca acaggatact ccagccgagg
     4201 gagggcgtcg tctaccttga cgggaaagac ctcttccggc tggatggcag cgagattgcc
     4261 cggaacatcg ggtacgtccc ccagcggatc gagaccgggc ggctcaccgc gttcgatgcc
     4321 gttctcctgg gcaggaaacc ccacatcggg tgggatattt cggaaaatga cctccgcatg
     4381 gtggacgcag tcttccggag gctggccatg gagcacctgc gcctcgcgta catcgacgag
     4441 atgagcgggg gcgagctcca gaaggtggca atcgcccgcg ccctcgtgca ggagcccagg
     4501 atcctcctcc tcgacgagcc gacgagcaac ctcgacctga agaaccaggt cgccatcctc
     4561 tcgacgattg cccggatcgt gcgcgaacac ggcatttctg ccgtcatgac gatgcatgac
     4621 ctcaaccatg ccatccggta tgccgaccgc ttcatcttcc tccggaacgg acgtatccat
     4681 gcgcacggcg gcccggagac gatcacacca aagaccatcg aggaggtcta cggcctgccc
     4741 gtcatcatcg gaaaactcgg cggggtgacc tgcatcgtgc cggagagcag cccggtttcg
     4801 accggcgcat gaccaccaga acaccaggga gacacaagaa ccatgtgcga gaaccatgaa
     4861 ggggcccgcc acgggcccgc gtatcctgcc ttcgacgagt gcgtccgttt ccacgggcac
     4921 tcgtgtcccg gcctcgcgac cgggtaccgc gttgcgatcg ccgcgatgaa ggcactttcg
     4981 gtgaaccgcc ccttcgacga ggaactcgtc tgcgtcgcag agaccgacgc ctgcggcgtg
     5041 gacgcagtcc aggttgtcac gggctgcacg gcaggaaagg ggaacctcgt catccgggac
     5101 tggggcaaac acgcgttttc gttcttttcc cgggacagcg ggaaggcagt ccgtgtcctc
     5161 gtgaagaatt cccacatgcc cggcaggtcc gcgatggacg acctgcgcag gaaggtcttt
     5221 tccgggactg ctacgccgga ggagacggcc cggttccacg cgatgatggc ggaaacgacg
     5281 cggtccctcc tctcggtacc cgaatccgac ctgctcgaga tccgcgaact ggcggaaaag
     5341 ccaccggaaa aagcgcggat ctttgcatcc gtcgtgtgcg aggcgtgcgg tgagccggtg
     5401 gccgacgcac ggacgagggt cgttcgcggc aggcgggtct gcattccctg ttcccttgca
     5461 ggggagagcc cggaaagacc atgaccccgg cacccctcga actggtcccc atcgggtacg
     5521 tgcgctcgcc gttccgcggg aggaaggacg caccccggca ggggaggctt gcgcccgtcg
     5581 tctccgagat cgtggtccgc ccggagttcg aagacggtct tttccggctc gacgaaaaga
     5641 cgcatctctt cgtcctgtgc tggttcgaca gggccgacag gacgaagctc cgggccatcc
     5701 cgccccacga ccccgtggaa cgcggcgtct ttgcgacccg ctcgcccgac cgtccaaacc
     5761 ctgtctccct caccctcgtc gacctcgttt ccatcgacgg ccgtgtgctt tccgtccggg
     5821 ggctcgatgc cctcgacgga acaccggtca tcgacatcaa gccctattcc gaagatatcg
     5881 acaggccgca cgaatagtcc ggggacagtc cgcgggaga
//
LOCUS       DAOOJU010000052         5895 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_10988_length_5895_cov_16.642979, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000052 DAOOJU010000000
VERSION     DAOOJU010000052.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5895)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5895)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5895
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10988_length_5895_cov_16.642979"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..604
                     /locus_tag="PK679_08850"
     CDS             <1..604
                     /locus_tag="PK679_08850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="formate dehydrogenase"
                     /protein_id="HPC56098.1"
                     /translation="GDKAGKATFVEVCSEKGANILDQAVKAGAIKTEPADPKGIEMRK
                     KVEGAMLKLGDKWREKDFASLGTGRERLQKIVRETSRCIKCYQCIENCPICYCVECST
                     KKPYLVNPGQVPPSFMFHLIRFAHIADSCVNCGQCQELCAMDIPNALFMHAQQVELEK
                     MFGHVPGVDMKLPLLALVEEREERARLAATGSDQIFDIFK"
     gene            complement(806..2431)
                     /locus_tag="PK679_08855"
     CDS             complement(806..2431)
                     /locus_tag="PK679_08855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HPC56099.1"
                     /translation="MGTPEENVQDACSRDEKPLLRGIPYASDIYRRWEKIYNDIKQIA
                     AGGVRGTTIEALYENTRGPREVPPGHPLPVVGFSCMTREPADDEIPGLVDEAIRQVLG
                     PRGLSALIKKGDRVVIKVNIVGPSHGLPGEKGRGIVSDPRIVRYVAGKVREIIGFGGT
                     ADLKVVDATFSPEKDPSDRNNPMSFHYARLQRSGGTSVHENDICYDYDADGVLDGGSG
                     ATLVNLDSVPHSERFLTVVDEPIRGRCEVWLPKFLRTREQAQGDPDYCDVYIGIPVFK
                     SHGFCGMTGALKLHWGTMLGALEKQEHAGYGFGTGDIRLFLDYLCAMNRARGFDLVIM
                     DALTGNRAGPMNNSDNPDARTDFILVNAILCSRDSVAIDTVETLLGGFRPDSVPLPEA
                     AFRDGIGINRPAYIDLKGFDAFFRHKRWLRETYPGCGPGSYPLQSGIGNAKTHEDFNA
                     PENVSVTCRKDGDVFMFDYTASEPAPCNHALARIDLLVNGTVVQRLFENLTGGSVLVD
                     LGEFCNQVVRYRIAAWDMALNCTLSEEKELMVA"
     gene            complement(2514..>5895)
                     /locus_tag="PK679_08860"
     CDS             complement(2514..>5895)
                     /locus_tag="PK679_08860"
                     /inference="COORDINATES: protein motif:HMM:NF024753.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC56100.1"
                     /translation="GALYVGSNDNRVYSLGSSVPVPSFTASPASGPYPLTVTFTDTSQ
                     GNITGWHWDFGDGSSSTLRNPVHTYPGPGTYAVNLTVTGPRGTRSLVVPAAIQVTFDF
                     TGTPRNGQSPLTVTFSDTLPADTTGRNWDFGDGQTGTGKNPVHTYTTPGSFTVTLNAT
                     GPGWTATLVKKDYIGVSIIPDPTVRWKVRTGTTSIGSPPVLYNGVAYVDGGTTLFAVD
                     TRTGTERWRFATGAECSISEVYGGVVYVRAGTTLYALDAQSGSEKWRFDAPEKIGQPS
                     RYMGVICFNSGNSVYGIDINTGSEKWRVTKDDPFTEVTIGEGIVSGDLYAGSGKTLYA
                     IQTHTGKERWHKEYKNEVRLKPVVSANLVIFCTNAKTSQYVWDEFWTFHAVGMMDGKE
                     LWAVGPYSYSVGSLQITDGTFLFINNFRYHPGIHAVDLTTGRELWSYSAGDRYDAAKY
                     IVSGDTVLSCFGDHEEICSTYYCKSRDTWTLVSLDTKTGKKTWEKDLDYTVVIGLPVI
                     AHGNAYIGHTKTSKGNLMVVSMNNGTTLWDSQVGEGDLGWPVFSNGVVYAKGSDGYFY
                     AVGNPLSISATPTTGMSPLTVSFRDTTPQKTSAWLWDFGDGTTSSGQNPVHTYTLPGT
                     YTVTFTASDASGIVSYQKENYIRVMTNLSVTRIDPVNGIKNSTIPITITGGNFTGAMT
                     ANFIRGAIVIPVTDVTVVDSATISGTLVIPGGAPNGLYDLCITRPSDGNSVKVPEAFM
                     VLQYPAPTLISIDPASTKTGSLQKFTLAGSNFQIGATVVFTNPAGSRLTTTAVTNSSS
                     EIILTTTFPENGTGWWNVTVTNPDGGTATLSHALEVTPSNADVPPPAISSVSPAKGTA
                     GTSVALSIVGSGFTRGSSVKLCRGAVELPGSQVVVMKPTAMRTTVRIPGNAVPGLYDV
                     VVTSPEGQAGMLSGAVTIVNRNSPLLSGITPGTMTAGTTTAFSLTGDRFREGAVVVFS
                     NAMGAVMMADITSVTDRKITGTLSIPEGAETGPWSVSVTNPDGGTARISDAVTIKTPS
                     GDGGTGPAVISVKPESGSAGKTVGLIITGSNFSKGSSVSIRDGVSEIMASRVLTMDTT
                     KMFAILKIPANATPGAYDLVITDSQGRSGTLPSGFSVI"
BASE COUNT         1198 a         1738 c         1684 g         1275 t
ORIGIN      
        1 cggcgacaag gccggcaagg ccacgttcgt cgaggtctgc agcgagaagg gtgccaacat
       61 cctcgaccag gccgtcaagg caggtgcgat caagaccgaa cccgccgacc cgaagggcat
      121 cgagatgcgc aagaaggtcg agggcgccat gctgaagctc ggcgacaagt ggcgcgagaa
      181 ggactttgca tcgcttggaa ccggcaggga acggctccag aagatcgtca gggaaacatc
      241 ccggtgcatc aagtgctacc agtgcatcga gaactgcccg atctgctact gcgtcgagtg
      301 cagcacgaag aagccgtacc tcgtaaaccc cggtcaggtt cccccgagct tcatgttcca
      361 cctgatccgg ttcgcccaca tcgccgactc ctgcgtcaac tgcggacagt gccaggagct
      421 ctgcgccatg gacatcccga acgcgctctt catgcacgcc cagcaggtgg agctcgaaaa
      481 gatgttcggg cacgtcccgg gtgtcgacat gaagctcccg ctgctcgccc tcgtcgagga
      541 acgcgaggag cgcgccaggc ttgccgcgac gggaagcgac cagatctttg atatcttcaa
      601 gtaaaacctt ttttttcgcc aagaatcccc gcctgggaga aggtgcacct ctttatcctt
      661 tccccatccc gatcacaacg aggagcccgt tgccggggat ccccggatac cggcatgggt
      721 tgggaggggt attatcctcc ctttttcccc atcgggtggt ccatggcatt gcaggacaac
      781 ggactcctgt ccttccacga agggtctatg ccaccatcag ttccttctct tccgacagcg
      841 tgcagttgag tgccatgtcc catgcggcga tccggtagcg gacaacctgg ttgcaaaact
      901 ccccgaggtc aaccaggacg cttccaccgg tgaggttttc gaagaggcgc tgaacgacag
      961 tcccgttcac gaggagatcg atcctcgcga gtgcatggtt gcagggagca ggctccgatg
     1021 ccgtgtaatc gaacatgaaa acgtcgccat ctttccggca ggtgaccgaa acgttctccg
     1081 gcgcattgaa atcttcgtgg gtctttgcat tccctatgcc ggactgcagc ggatagctcc
     1141 cgggaccgca tccgggatag gtctcccgca gccatctctt gtgacggaaa aaagcgtcga
     1201 atcccttgag gtcgatgtat gccggcctgt tgatgccgat cccgtcgcgg aatgccgctt
     1261 cggggagggg gaccgagtcc ggccggaaac cgccaagaag cgtctcgacg gtgtcgatgg
     1321 ctaccgaatc ccgggaacag aggatcgcgt tcacaaggat gaaatcggtc cgggcatcgg
     1381 gattgtccga attgttcatc ggaccggccc ggttcccggt gagggcgtcc atgatcacga
     1441 ggtcgaaccc gcgtgcacgg ttcatcgcac acaggtaatc gagaaagagg cggatatcgc
     1501 ccgtgccaaa cccgtacccg gcatgctcct gtttctcgag tgccccaagc atcgtgcccc
     1561 agtggagctt gagagcaccc gtcatgccgc agaacccgtg gcttttgaac accggtatcc
     1621 cgatgtacac atcgcaatag tcagggtctc cctgtgcctg ttccctcgtc ctgaggaact
     1681 tcgggagcca tacctcgcac cttccccgga tcggttcatc gacaacggtc aggaaccgct
     1741 ccgaatgggg gaccgagtcg aggttgacga gggttgcccc tgaccctcca tcgagcacgc
     1801 cgtcggcatc gtaatcgtag cagatatcgt tctcatggac cgatgtgccc ccgctccgct
     1861 gcaggcgggc atagtggaag ctcatggggt tgttcctgtc cgaagggtcc ttctccggcg
     1921 aaaacgtggc atccaccacc ttcaggtctg ccgttccccc aaaaccgatg atctcccgca
     1981 ctttccccgc aacgtacctc acgatccgcg ggtccgacac gatcccccgg cccttctcac
     2041 cgggcagtcc atggctggga ccgacgatgt tgaccttgat aacgacccgg tctccctttt
     2101 tgatgagtgc agacaggccc cggggcccga gcacctgcct gattgcctca tcgacgagcc
     2161 cggggatctc gtcgtcggcc ggctcccggg tcatgcagga aaaaccgacg accggcagcg
     2221 gatgaccggg tggaacctcg cggggtcccc tcgtgttttc atacaaggct tcgatcgttg
     2281 tcccccggac acccccggcc gcgatctgtt ttatgtcatt gtatatcttt tcccagcggc
     2341 gatagatgtc gctggcatag gggatgccac gcaaaagggg tttttcgtcc cgggagcagg
     2401 catcctgcac attttcttcc ggcgtgccca tggggaatgt tcttctcccg gatttataaa
     2461 attaccaacc ccgatgccag aaaggggaag gagaagaagg ggtcctgtcc ccttcagatg
     2521 accgaaaaac cggaggggag tgtccctgac ctgccctggc tgtcagtgat cacgaggtca
     2581 taggcaccgg gtgttgcgtt ggcagggatc ttcaggattg caaacatctt ggttgtatcc
     2641 attgtcagta ccctggacgc cataatctcc gatacaccgt cgcggatgct gaccgaagaa
     2701 cccttcgaaa aattgctgcc cgtgatgatc aagccgacgg tctttcctgc cgaaccgctc
     2761 tcaggtttca cggagatgac agcaggcccg gtcccgccat cgcccgacgg ggttttaatt
     2821 gtcacggcat cggaaatccg ggcggtgcca ccgtcgggat tcgtgaccga aacactccat
     2881 ggtcccgttt ccgctccctc cggaatgctg agcgttcctg tgatctttct gtccgtgacg
     2941 ctggtaatat cagccatcat gaccgcgccc atggcattgg aaaagaccac cacggcaccc
     3001 tcacggaagc ggtctccggt gagcgaaaaa gccgtggtgg ttccggcagt catggtccct
     3061 ggcgttatcc cggagagcag gggggaattc ctgttcacga ttgtgaccgc gcccgaaagc
     3121 atccctgcct gtccctccgg gctggtgacc acgacgtcgt acagcccggg gactgcgttg
     3181 ccagggatcc tgaccgtggt acgcatcgcc gttggcttca tgacaacgac ctggctgcct
     3241 ggcagttcaa ccgctcccct gcacagtttc accgacgacc cgcgggtaaa gcctgacccc
     3301 acgatcgata gcgcaaccga cgtcccggct gtcccctttg cagggctgac agaactgata
     3361 gcgggtggcg ggacgtctgc gttggacggc gtcacttcga gtgcatggga gagcgttgcc
     3421 gtcccgccat cgggattggt aaccgtgaca ttccaccagc cggtcccgtt ttccgggaac
     3481 gtggtggtca ggatgatctc ggacgagctg ttcgtaaccg cggtggtcgt cagtctgctc
     3541 cctgccggat tcgtaaagac gaccgtcgcg ccgatctgga aattgctgcc ggcaagggtg
     3601 aacttctgca gggaaccggt tttcgtggag gcgggatcaa tcgagatgag ggtgggagca
     3661 gggtactgga ggaccatgaa cgcctccggg actttgacac tatttccatc agatggtctg
     3721 gtgatgcaga gatcgtagag gccgtttggt gcaccgccag gaatcacaag cgtgcccgag
     3781 atggttgcgc tgtccaccac ggtgacatca gtgaccggga taacaattgc ccccctgatg
     3841 aaatttgccg tcatcgctcc cgtgaagttg ccgcccgtga tggtgatcgg gatggtcgag
     3901 tttttgattc cgttgacagg atcaatgcgt gtcaccgaga ggtttgtcat caccctgatg
     3961 taattttctt tctggtaact gacgatccct gatgcatccg atgccgtgaa cgtgacggta
     4021 taggtgccgg gcagggtata ggtatgcacc gggttttgcc cggaacttgt ggtcccgtca
     4081 ccgaaatccc ataaccacgc agatgtcttt tggggcgtcg tatcccggaa tgacacggtc
     4141 aggggtgaca tgccggtagt tggtgtcgcg gagatggaaa gcgggtttcc gaccgcgtag
     4201 aagtatccgt ctgacccttt tgcatagacc acaccgttgg agaacaccgg ccatccaaga
     4261 tcgccctctc ccacctgtga atcccacagg gtggtgccat tattcatgct caccaccatg
     4321 agattgccct tggaagtctt tgtatgacca atataggcat taccatgggc tataacaggg
     4381 agacctatta ccactgtata atcgagatcc ttttcccagg tcttctttcc tgtctttgta
     4441 tccagcgaca cgagtgtcca ggtatcccga cttttacagt agtaagtact gcatatttct
     4501 tcgtggtccc caaaacagga aagtaccgta tctcctgaca cgatgtattt cgcagcatca
     4561 tatctgtcac cagcggaata ggaccagagt tccctgccgg tcgtgaggtc tacggcatga
     4621 atccctggat gatatctaaa attgtttata aacaggaaag ttccgtcagt gatttggaga
     4681 gatccgacgg aataactata gggtccgacg gcccagagtt ctttgccatc catcatcccc
     4741 actgcatgga acgtccagaa ctcatcccag acatactgag atgttttggc gttcgtgcaa
     4801 aaaataacca ggttggctga caccaccggc tttaaccgga cctcattctt atactccttg
     4861 tgccaccgct ccttaccggt atgcgtctgg attgcataga gtgtctttcc gctccctgcg
     4921 taaagatcgc ctgatacaat gccttccccg atggtcacct cggtaaaggg atcgtccttt
     4981 gtgacccgcc atttctcgga tcctgtgttt atgtcaatac catagaccga attccccgag
     5041 ttgaagcaga taacccccat gtaccgggac ggctggccga tcttttcagg ggcatcaaac
     5101 ctccattttt ccgaaccgct ttgtgcatcg agagcataca gggttgtccc ggcccttaca
     5161 tagaccactc ctccgtagac ttctgaaatg gaacattccg caccggtcgc aaaacgccag
     5221 cgttccgtcc ctgtccgcgt atcaaccgca aagagagtcg ttcccccgtc aacataggca
     5281 acaccgttgt acagaacagg gggcgaacca atcgacgtgg ttccggtccg gactttccag
     5341 cgaaccgtgg ggtcggggat gatgctcact ccgatgtaat ccttcttgac aagcgttgct
     5401 gtccacccgg gaccggtcgc attcagcgtg acggtgaagg atccaggtgt ggtataggtg
     5461 tggacggggt tcttcccggt gcccgtctgt ccgtccccga aatcccagtt cctgcccgtg
     5521 gtgtctgccg ggagggtgtc ggagaatgtg acagtcaggg gagattgtcc gtttcgcggg
     5581 gtcccggtaa agtcaaaggt gacctggatt gcggccggca caacgaggct tcgcgtccct
     5641 ctcggtcctg taaccgtcag gttgaccgca tacgtcccgg gaccgggata ggtatgcacc
     5701 gggttccgga gggtgctcga actcccgtcc ccgaagtccc agtgccagcc tgtaatgttc
     5761 ccctgggagg tgtcggtaaa ggttacggtc agggggtacg gcccgcttgc cggggatgcg
     5821 gtaaacgagg ggacgggtac gctggagcca agggaataga ccctgttgtc gttactcccc
     5881 acgtagagag cacca
//
LOCUS       DAOOJU010000053         5656 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_11510_length_5656_cov_14.947866, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000053 DAOOJU010000000
VERSION     DAOOJU010000053.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5656)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5656)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5656
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11510_length_5656_cov_14.947866"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(23..1108)
                     /gene="cofH"
                     /locus_tag="PK679_08865"
     CDS             complement(23..1108)
                     /gene="cofH"
                     /locus_tag="PK679_08865"
                     /EC_number="2.5.1.147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(D-ribitylamino)uracil--L-tyrosine
                     4-hydroxyphenyl transferase CofH"
                     /protein_id="HPC56101.1"
                     /translation="MRAIKEILAGARGGDRLTEGEALTLLSAKGREIFDICRAADELR
                     EEKVGPTVTFVRNQNIHLTNICKNLCGFCAFGRRATDEGAFCDDPETLRNKVRQARKN
                     RVTEICLLSGVHPDFDASRYAGILSCVRETAPGIHIHAFSPDEVSHAAARSGLTTREV
                     LEMLKNAGLGSLQGTAAEILVDSVREVICPSKVSTAEWVRIIREAHALGIFSTATIMY
                     GSCETAADRVTHLSILRDIQDKTGGFSELVPLSFLHQNTRLYLQGLAPAGATGREDLL
                     MIAVSRLFLDNFQNIQVPWGKVGLKLAQLALQSGANDLAGTMFSDDVSGSAGALGADY
                     FDPAEMERICRDIGRTLRQRLTDYTLV"
     gene            complement(1131..1985)
                     /locus_tag="PK679_08870"
     CDS             complement(1131..1985)
                     /locus_tag="PK679_08870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014866123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
                     /protein_id="HPC56102.1"
                     /translation="MSHEEKNDTEKGLLQRFLTSSNRWVSLARELAWVAAVVGGIALA
                     LFLVSGTWPAVVTIESESMVPHMNVGDLVFVVSADRFGELQTWTTGKETGYQKFGDYG
                     DILIYRPNDAPNPPVSIPFITGGVHPIIHRAMDKIGEGETIPKYYNVYRGQATPARYV
                     PATIRNNSLVLMDGTVVTPQNADPLVGYVVQTGIKSPHAGYITKGDNNLVSDQGGYLS
                     SVSGQVIMPVREDWVVGKALFTIPLLGYLPLNIVPVAVILIAFMIVWEYHSKKKERSA
                     GKKGKKKR"
     gene            2158..3555
                     /locus_tag="PK679_08875"
     CDS             2158..3555
                     /locus_tag="PK679_08875"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011842901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed DNA polymerase II small subunit"
                     /protein_id="HPC56103.1"
                     /translation="MLDAATIVQRFLETKLQVHPEVVRYIAEKDDPGLIDRIIANVPG
                     DAVVVSVRHIPGLHPDRDGSRFLTDPECEVIRGTAGSSRAIASVADYSAYFRDRYQRL
                     GECIRARAAPMPIEALKKGSRYRQEACSIMGLVVENRTTANGHRMVEVEDPTSSIQVL
                     FHKDRPQFAEAETLVPDEVIGVRGTLSGDGRLFFAEQMFRPDIPLSHAPFRSEKPGQA
                     VLISDVHVGSNTFLEETWNRFADWLSGSDVSYLLIAGDLVDGIGVYPNQDHELTIKNI
                     YEQYEVFGSMLRDLPSRMKIIISPGNHDVVRQAEPQPAIPPEFSANFPKNCIMVENPA
                     MVSLQGVRVLMYHGRSLDDFISLIPGASYDNSAPVMAGMLQRRHLAPTYGKRTPIAAG
                     KEDPLIIDPIPEVLHTGHIHIMGVSDYRGVLCVNSGTWQSQTAFQKQMNITPTPGRAV
                     LLDLQTLGYSVLDFN"
     gene            3648..>5656
                     /locus_tag="PK679_08880"
     CDS             3648..>5656
                     /locus_tag="PK679_08880"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-translocating pyrophosphatase"
                     /protein_id="HPC56104.1"
                     /translation="MDMFLIVPVCALLGLVFAGYSFTVMKREGTGTELMQKIAGAIRL
                     GSMVYLRSQYKAIAVFVIVLAIVLYIIPGIHPLTSVAFLVGAALSATAGFIGMSAATM
                     ANVRTTNAAREGMARAFRVSYASGTVMGLTVVGLGLMGLSLLFLALNSFTTLGLSEII
                     SILSGFSLGASSIALFARVGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVG
                     DNVGDIAGMGADLYESYVGSIVATMLMGVSVLAAAKFAGVATMNLVLLPMLIAGLGII
                     ASIIGSFFVRSSKNESGAIHKAFNTGTFVSLLLTVAAVYYLVTTLLGPQYIGVFVATV
                     AGLVAGFLIGLVTEFYTSYERSPTQKIAKASETGAATNIITGLAVGFESTLFPVLIVV
                     VAILVAAQQAGLYGVAIAGVGMLATLGITLSVDAYGPVADNAGGIAEMSHQPKEVRAI
                     TDTLDAVGNTTAAIGKGFAIGGAALTALGLFAAYSQAVRLEIVNMLEPVVFVGVLIGA
                     MLPFLFCSFAMTAVGKAAGYIVQEVRRQFKEIPGLMEGRTDPDYGACITISTNAALRQ
                     MIAPGVMAIAAPLVVGLTLGTHALAGLLVGSIASGFIVAVMMANTGGAWDNAKKYIEQ
                     GHLGGKGSSAHKAAVTGDTVGDPFKDTAGPALNILLKLMAIVSVV"
BASE COUNT         1061 a         1745 c         1646 g         1204 t
ORIGIN      
        1 ctcctggtcc ggggactgac gatcagacca gcgtataatc cgtgagccgc tgccggagag
       61 tgcggccgat atcacggcag atgcgttcca tctctgccgg atcgaaataa tccgccccca
      121 acgccccggc actcccggat acgtcatcgg aaaacattgt tcccgccaga tcgtttgcac
      181 ctgactggag cgcaagctgg gccagcttga gcccgacctt cccccaggga acctggatgt
      241 tctggaaatt atcgagaaac agccgggaga cagcgatcat gaggagatcc tcccttcccg
      301 tcgctcccgc aggagcgagc ccctgcaggt agagtctcgt gttctggtgg agaaaggaga
      361 gggggacaag ctcggagaaa ccacccgttt tgtcctggat atcccgcagg atggaaagat
      421 gcgtgacccg gtctgcagcg gtctcacacg acccgtacat gattgttgca gtggaaaaaa
      481 tgcccagtgc atgcgcctcg cgtatgatcc gcacccactc tgctgtggaa accttggacg
      541 ggcagatgac ctccctcacg ctgtccacga gaatctcggc tgccgttccc tggagtgagc
      601 cgagtcctgc gtttttcagc atttccagaa cttcccgggt cgtaagcccc gatcgtgctg
      661 cggcatggct cacttcgtcg ggagagaatg catggatgtg gatccccggg gcggtctccc
      721 tgacacagga gaggatcccg gcataccggc tggcatcaaa gtccgggtgg acgccggaga
      781 ggaggcagat ctcggtaacc ctgttcttcc gggcctggcg gaccttgttc cggagggttt
      841 caggatcatc gcagaatgcc ccctcgtctg ttgcccgccg gccgaatgcg cagaaaccac
      901 agaggttctt gcagatattc gtaaggtgaa tgttctggtt gcggacgaag gtcacggttg
      961 gtccgacctt ctcctcgcgc agctcgtccg ctgctctgca aatatcgaat atttcgcggc
     1021 ccttcgccga caggagggta agggcctctc cttcagttaa ccggtcacct ccacgggcac
     1081 cggcaagtat ctcctttatc gcccgcacta cttcccctta ccccctcttc tcacctcttc
     1141 ttcttccctt tctttccagc gctgcgttcc ttcttcttcg agtggtattc ccacacaatc
     1201 atgaacgcga tgaggatgac tgccaccggg acgatgttga ggggcaggta tcccaggagc
     1261 ggtattgtga acagggcttt gccaaccacc cagtcctccc ggacgggcat gatgacctgc
     1321 ccggacacgg aggagagata ccccccctgg tcactgacga ggttgttgtc tcccttggtg
     1381 atgtacccgg catgcgggct ctttattcct gtctgcacca cgtatccgac cagcgggtcg
     1441 gcattctgtg gtgttacgac agtcccgtcc atgagaacga ggctgttgtt ccggatggtc
     1501 gccgggacgt accgggcagg tgttgcctgc ccacggtaga cattgtagta cttggggatg
     1561 gtctcgccct ccccgatttt atccatcgcc ctgtggatga tggggtggac accccccgtg
     1621 atgaacggga tggatacggg gggattgggt gcatcgttgg gccggtagat gaggatgtcg
     1681 ccgtagtcgc cgaacttctg gtacccggtc tccttcccgg tcgtccacgt ctggagttcg
     1741 ccgaaccggt cggcgctgac cacgaagacc aggtcaccga cattcatgtg cgggaccatg
     1801 ctctccgatt ctatcgtcac gaccgcgggc cacgtgcccg aaacgaggaa cagtgcaagg
     1861 gcgattcctc caaccaccgc ggccacccat gcaagctcgc gggcaaggga gacccagcgg
     1921 ttgctgctcg tgagaaatct ctgcaggagg cccttttcag tgtcattttt ttcttcgtgc
     1981 gacattcctg gaccctgatc tatttttttc caggcatgat aaggaatcgc acccggaacg
     2041 gcatatcccg tccggggtct aaccgttctc ttacagaggg agcgattcgg gagtgtttcc
     2101 cgggtcccat ggagcaggag tgaaaaccct atatcgggca ctgtccatat atgatcgatg
     2161 ctcgatgcgg caaccatcgt ccagcgtttc ctcgagacga agctccaggt acacccggaa
     2221 gtcgtccggt acatcgccga aaaggacgat cccggtctta tcgaccgcat cattgcaaac
     2281 gtgcccggcg atgccgtcgt ggtctcggtc aggcacatac ccggtctgca ccctgaccgt
     2341 gacgggagcc ggttcctgac cgaccccgag tgcgaggtga tcaggggcac agccggttca
     2401 tcccgggcca ttgcgagcgt tgcagattat tctgcctatt tcagggacag gtaccagcgc
     2461 ctgggcgagt gcatccgggc aagggcagcc cccatgccaa tcgaggcatt aaagaaggga
     2521 tcacgctacc gtcaggaggc atgctcgatc atggggcttg tcgtggagaa ccggaccacg
     2581 gcaaatggcc atcgcatggt ggaggtggaa gatcccacct cctccatcca ggtcctcttc
     2641 cacaaggacc ggccccagtt cgcggaagcc gagacgcttg tccccgacga ggtcatcggc
     2701 gtccggggga cgctgtccgg tgacggaaga ctcttttttg ccgaacagat gttccggccc
     2761 gatatcccgc tctcccatgc accgttccgg agcgaaaaac ccgggcaggc agtcctcatc
     2821 tccgatgtcc atgtcgggag caatacgttc ctcgaggaga cgtggaaccg ttttgccgac
     2881 tggctctccg gctcggatgt ctcctacctg ctcatcgcag gcgacctcgt cgacgggatt
     2941 ggcgtctacc cgaaccagga ccatgaactg acgataaaga atatctacga gcagtacgag
     3001 gttttcgggt caatgctccg ggatctcccc tcccggatga agatcatcat ctctcccggc
     3061 aaccacgatg tggtgaggca ggccgagccc caacctgcca taccccccga attttccgcg
     3121 aatttcccca aaaactgcat catggtcgag aacccggcga tggtgagcct ccagggcgta
     3181 cgggtcctga tgtaccacgg gaggtcactc gatgacttca tcagcctgat ccccggtgcg
     3241 agctacgaca actctgcccc cgtgatggcc ggtatgctgc agcgtcgcca cctcgcaccc
     3301 acctacggaa agaggacccc gattgcagcc gggaaggaag accccctgat catcgacccc
     3361 atcccggaag ttctccacac cgggcacatc cacatcatgg gggtttctga ctacaggggt
     3421 gttctctgcg tgaactcggg aacctggcag tcacagacgg cgttccagaa gcagatgaac
     3481 atcaccccga cgccaggccg tgcggttctc ctcgacctcc agacactggg ttacagtgtc
     3541 ctcgacttca actgatatca gccgcctttt tatgcacggg aatcaattga tctcagacgc
     3601 aacaggtatg cgtggagacc ggttgggttc tccggaggtt ctgtgctatg gatatgttcc
     3661 tcattgttcc tgtctgtgcc ctgctcggcc ttgtgtttgc cgggtactcc ttcaccgtca
     3721 tgaagaggga gggtacaggg actgaattga tgcagaaaat cgccggtgcc atccggcttg
     3781 gctcgatggt ctatttgagg agccagtaca aggcaatcgc agtcttcgtg atcgtccttg
     3841 ccattgtgct ctacatcata ccgggcattc accccctgac ttcagtcgcg ttcctggtgg
     3901 gtgccgccct ttccgcaacg gcagggttca tcgggatgtc agcggcaacg atggcgaacg
     3961 tgcggacaac gaatgccgca cgcgaaggga tggcccgggc attccgggtc tcctacgcgt
     4021 ccgggaccgt gatgggactg actgtcgtcg gccttggcct catgggtctc tccctcctct
     4081 tcctcgcgtt gaattcattc accacgctgg ggctatccga gatcatcagc atcctgtccg
     4141 ggttctcact cggtgccagt tccattgccc tctttgcccg cgtcggtggc ggtattttta
     4201 cgaaggctgc agatgtgggt gcagaccttg tcggcaaggt ggaggccggc atcccggaag
     4261 acgacccgag gaacccggca gtcatcgctg ataacgtcgg ggacaacgtc ggggacatcg
     4321 ccgggatggg agcagacctc tacgagtcgt acgtgggttc catcgttgca acgatgctca
     4381 tgggagtctc cgtccttgca gctgcaaagt tcgcgggagt cgccaccatg aacctcgtgc
     4441 tccttccgat gctgatcgca ggccttggta tcatcgcgtc catcatcggg agtttctttg
     4501 tccggagctc gaagaacgag agtggtgcca ttcacaaggc gttcaacacg ggcactttcg
     4561 tgagcctcct cctcacggtg gcagccgtgt actacctcgt gacaacgctc cttggtcccc
     4621 agtacattgg cgtctttgtc gcgaccgtcg ccggcctcgt cgcaggtttc ctcatcgggc
     4681 tcgtgaccga gttttacaca tcctacgagc ggtcaccgac ccagaagatt gcaaaggcga
     4741 gcgagacggg tgctgcaacg aacatcatca ccggccttgc cgtcgggttc gagagcaccc
     4801 ttttccctgt cctgatcgtt gtcgttgcca tcctggtcgc cgcacagcag gccggtctct
     4861 acggcgttgc catcgcgggt gtcgggatgc tcgcgacgct cgggatcacc ctctcggtgg
     4921 acgcgtacgg gccggtcgcg gacaacgccg gtggtatcgc cgagatgtcc caccagccca
     4981 aggaggtcag ggcgattacc gataccctcg acgcagttgg aaacacgacg gccgccatcg
     5041 gcaagggctt tgcaatcggc ggggctgcac tcacagcgct cggtctcttt gcagcctact
     5101 cccaggctgt ccggctcgag atcgtgaaca tgctcgagcc ggtcgtcttc gtcggcgtgc
     5161 tcatcggtgc catgctcccc ttcctcttct gctcctttgc catgactgcg gtcggaaagg
     5221 ctgcgggcta catcgtccag gaggtccggc gccagttcaa ggagatcccg gggctcatgg
     5281 aaggcaggac cgaccctgat tacggcgcct gcatcaccat ctccacgaac gccgctctca
     5341 ggcagatgat tgctccgggc gtgatggcca ttgccgcacc ccttgtcgtc ggcctcaccc
     5401 tcggtaccca tgcactcgcc ggtctcctcg tcggatcgat agcgtcaggg ttcatcgtgg
     5461 ccgtcatgat ggcaaacacg ggtggtgcct gggacaacgc caagaagtac atcgagcagg
     5521 gtcacctggg aggaaagggg tcttctgccc acaaggcagc ggtcacgggt gacacggtcg
     5581 gggatccgtt caaggacact gcgggaccgg ccctcaacat cctcctgaag ctgatggcca
     5641 tcgtctcggt ggtctt
//
LOCUS       DAOOJU010000054         5609 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_11632_length_5609_cov_7.065358, whole genome shotgun sequence.
ACCESSION   DAOOJU010000054 DAOOJU010000000
VERSION     DAOOJU010000054.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5609)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5609)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5609
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11632_length_5609_cov_7.065358"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            364..>1702
                     /locus_tag="PK679_08885"
     CDS             364..>1702
                     /locus_tag="PK679_08885"
                     /inference="COORDINATES: protein motif:HMM:NF028468.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE3 domain-containing protein"
                     /protein_id="HPC56105.1"
                     /translation="MNPIPKDVLCNHRDVLLESAGIVAVLLVLAIISTYNYLVFHSII
                     EIFTIVVSFSIFFLIWNGRKYIDNGFFIILGAGFLFSGGIDIVHTLAYKGMGVFSFGG
                     ADLPTQLWIAARYLQASSLLLAPFAIGRKVRFLPTLIAFGAVFSILLWSIFAGFFPHC
                     YIEGQGLTPFKVSSEYAISGILILSVLLLIRARDAFDPSVFSYLVLANAFTIAAGLSF
                     TAYVSVYGFANMLGHLLRLVAVFLWYRAFLVVGVNRPYDLLWRELTRERDRVRESEER
                     FRSLFDHMLEGFAYCRMIYDESGRPSDWEYLKVNPSFEKLTGLSDVVGKKVTDVIPDI
                     REKNPELFEIYGRVAATGQPAEIELFFKPLSIWLHISVFSPEKDHFVAVFENISRRKN
                     AEIALRESEAKFRHIAENAKDLIYRYELFPVRRFSYVSPSATSITGYTPGDHYA"
     assembly_gap    1703..1802
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <1803..2831
                     /locus_tag="PK679_08890"
     CDS             <1803..2831
                     /locus_tag="PK679_08890"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase dimerization/phosphoacceptor
                     domain -containing protein"
                     /protein_id="HPC56106.1"
                     /translation="VSPSATSITGYTPGDHYADPDLGLKIVHEDDRPLLASVFSDPDV
                     LSRPLVLRWRRKDGQVIWTEQHNRPVYDGEGRLIAIEGIARDVTERKQMESEILSLNR
                     ELEQRVAERTEELRKANVLLREEVAQRKKAEEDLKKRLDERTVLLRELYHRVKNNMQV
                     IISLMNLQLRKIEDPAVRHLMEETRNRVRAMALVHEMLYKSENLSEINLARYIPLLAS
                     QVFSSLENKSQKVRKIVEAEDIMVTLDKAIPVGLILNELITNSLMHAFPEGRAGTLGI
                     RVQKKDHTVAIRVSDDGTGIPQDVNWREPSTLGLRIVMSLVGQLKGTIDLDRRQGTAF
                     SIEFGIGE"
     gene            2864..5071
                     /locus_tag="PK679_08895"
     CDS             2864..5071
                     /locus_tag="PK679_08895"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56107.1"
                     /translation="MQEIEEKMTTVHERSLWNRIPGRNAWNAAIILFSGGAIVLTLYC
                     SLLGITTVFMHIYYIPIVLLAYRYRWSGMGGIATLVLAYLAITGLFFQHETMVILTAL
                     ARSVVFIAIGAIIAALSERILQVQKETEKSRNLKESIIRNANVWLMVLDSGGYVQEWN
                     TGAERISGYTAREVIGRNDIWKKIYPDGEYRKAITGKIRDIIEKNRYFENLETTITCR
                     DGSEKVMLWNTRSLFAGEKGEKEVFVAIGTDITAIRRAEEEVRESKKFLEEILNTINV
                     RVFWKDRNLVYMGCNRSFARDAGYDRPEDVIGKDDFQMPWKDLAERYRADDRIVIETG
                     SPRMTYEEPLTTPAGETLSLLTSKVPLSDLKGNTIGVLGVYVDISDLKKAERALKESL
                     NRTEAILKALPDLLFVISSDGIFHEFHCADEGVLVHSPGEYVGKSIWSFGYPKESGDE
                     FIRHVKTAIETGKIQYFSYDLTIRGKKRYFEARIAALNEDRALVIARDITDRVERERM
                     QERFTSELEEQVRHRTESLEAALHEKELLLREIHHRVKNNLQVIISLINLQVRITEKS
                     GATDILLDTQNRIRAMALVHEKLYQSGDLSRINIASYLRSLISQVSAYYGTKKQKVTL
                     SIACESLSMDINRAIPLGLIINELASNSLKHAFPGDREGTVTIRVERRDDRIECTVSD
                     DGVGLPPGFTIEESGSLGLRLVATLAKQLHGGIERIPTEKGTMFRLVIPGGEE"
     gene            5068..>5609
                     /locus_tag="PK679_08900"
     CDS             5068..>5609
                     /locus_tag="PK679_08900"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC56108.1"
                     /translation="MRGIQHRVRILIVEDEQIVAEDLRQTLENMGYSVVGVVSSGEGA
                     VETAHKEIPDLILMDIMLSGKMDGISAAHQIRSEHDIPVIYVTAYADSQLIERAKVTE
                     PFGYIVKPFNEREFQSNIEIALFKHRLEKEIRKRDAILLALGFGVEWFLRQVYEAHGA
                     LLSGSPVTFGYHLEPILEHVG"
BASE COUNT         1349 a         1470 c         1500 g         1190 t
ORIGIN      
        1 cccggtcagc ccgatgacga gcccgaggag gtatgtctgg agcatcttct cacggcctga
       61 ttatccatgg tactgttctc cttcgcaggt atcgtacctt tctatgggga gaatggaaga
      121 gggaaagaaa acgggctttg cccggtggga cttttacctt tcatgatgtg gcccgccaga
      181 accccccacg agggtgcgcg atggtgctca tgccaaccgc accatgggga acaaggaaat
      241 cccgcatcat gcctgcaata tttcgcgtat ccggtgggca tcccaggaca ttcattggtt
      301 atatgatagt gcggaaaaaa gatacccgtg cccgtccaag gagtcatcag ggagccttcc
      361 gaaatgaacc cgatccccaa agacgttctt tgtaaccatc gggacgttct cctggaatca
      421 gcaggtatcg tggctgtcct cctcgtcctt gccatcatca gcacttacaa ttacctcgtg
      481 ttccacagca tcatcgagat attcaccata gtcgtctcct tctccatctt ttttctcatc
      541 tggaacggca gaaagtacat tgacaacggc tttttcatca tcctgggcgc aggttttctc
      601 ttctcgggag gaattgacat cgttcatacc ctcgcataca aggggatggg ggtcttttcc
      661 tttggcggag cagacctgcc gacccagctc tggattgcag cacgttacct tcaggcatcc
      721 tcccttctcc tcgccccgtt cgcgatcggg agaaaggtcc ggtttttgcc cacccttatt
      781 gcatttggag cggtcttttc gatccttctc tggtctattt tcgcgggatt cttcccccat
      841 tgttacatcg agggccaggg tcttacaccc ttcaaggtct ccagcgagta tgccatatcg
      901 ggaatcctga tactctctgt ccttctcctc atccgggcga gggacgcatt tgatccttct
      961 gtattctcgt atcttgtcct ggcaaatgcc ttcaccattg ctgccggatt atccttcaca
     1021 gcatacgtga gtgtctatgg atttgcgaac atgcttggcc acctcctccg ccttgttgca
     1081 gtgttcctgt ggtaccgggc cttcctcgtt gtcggtgtga acaggccgta tgaccttctc
     1141 tggcgcgaac tgaccaggga gagggacagg gttcgcgaga gcgaggagag gttccgctct
     1201 ctctttgacc acatgctcga gggttttgct tattgcagga tgatctacga tgagtcaggc
     1261 aggccaagcg actgggaata cctgaaggtt aatccatcat ttgaaaagct gacgggctta
     1321 tcagacgtcg ttgggaaaaa ggtcaccgac gtcatccccg atattcggga aaaaaatccc
     1381 gagctgttcg agatatacgg gagggtcgca gcgacgggac aaccggcaga aatcgagctg
     1441 ttttttaagc cactttccat atggttgcac atctctgttt tttctccgga aaaggaccat
     1501 ttcgtcgcgg tgtttgaaaa tatcagccgg aggaaaaatg ccgagattgc gctccgcgag
     1561 agcgaggcaa agttcaggca cattgccgaa aacgcaaagg acctgattta ccggtacgaa
     1621 ctattcccag tgcgccgttt ttcctacgtc tccccttcag ccacctccat taccggttat
     1681 actcccgggg accattacgc agnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1801 nngtctcccc ttcagccacc tccattaccg gttatactcc cggggaccat tacgcagacc
     1861 cggatctcgg tctgaaaata gtgcacgagg atgaccgccc cctgctcgca tccgtctttt
     1921 cagatccgga tgtgctctcc agaccccttg ttctccggtg gaggagaaag gacgggcagg
     1981 ttatctggac cgagcagcat aaccgtccgg tgtacgacgg agaggggagg ctcattgcca
     2041 tcgagggcat tgcccgggat gttacggaga ggaagcagat ggaatccgag attctctccc
     2101 tcaacaggga gctcgaacag agggttgcgg agaggaccga ggaactccgg aaggcaaatg
     2161 ttctgctccg ggaggaggtc gcgcagagga aaaaagcgga agaggacctg aaaaagagac
     2221 tggatgaaag gacggtcctc ctccgtgaac tctaccacag ggtcaagaac aacatgcagg
     2281 tcatcatcag cctcatgaac ctccagctcc ggaaaattga ggatcccgcg gtcaggcatc
     2341 tgatggagga gacccggaac agggtcaggg caatggcact cgtccacgag atgctctata
     2401 aatccgaaaa tctctcggag atcaacctcg cccggtatat tcccctcctg gcaagccagg
     2461 ttttttcatc ccttgaaaat aagagtcaga aagtaagaaa gatagtcgaa gcagaggata
     2521 tcatggtcac cctcgacaag gcaattcccg tcggcctcat cctcaacgag ctgatcacca
     2581 attcgctcat gcacgcattc ccggagggac gggcagggac actcggtata cgagtccaga
     2641 aaaaagacca tacggttgcc atccgggtga gtgacgacgg gacagggatt ccgcaggatg
     2701 tcaactggag agaaccatcc accctcggtc tgcgcattgt catgtccctt gtcgggcaac
     2761 tgaaggggac aattgacctt gatcggcgcc agggaacagc gttctccatt gaattcggga
     2821 tcggggaatg aacgtaaccc ctggagatcc acggtaaaac cagatgcagg agatcgaaga
     2881 gaaaatgaca actgtccatg aaagatccct gtggaatcgc ataccgggcc ggaatgcatg
     2941 gaacgcagcg atcatccttt tttcgggtgg agccatcgtc ctgacactat actgttccct
     3001 cctcggtatc acgacagtct tcatgcacat ttactatatc ccgatcgtac tgctcgcata
     3061 caggtaccgg tggtccggga tgggagggat tgctaccctc gtcctcgctt accttgcaat
     3121 aacgggatta ttttttcagc atgagacaat ggtcatcctc actgctcttg ccaggtcggt
     3181 ggtcttcatc gcaatcgggg caatcattgc tgcgctctcc gagaggatcc tgcaggtcca
     3241 gaaagagacg gaaaaatcca ggaatctcaa ggagagtatc atccggaatg caaatgtctg
     3301 gctgatggtc cttgactcag gcggatacgt ccaggaatgg aacaccggtg ccgaaaggat
     3361 aagcgggtac actgcacggg aagtcattgg ccggaacgat atatggaaga agatctatcc
     3421 cgacggggaa taccgcaaag cgattacagg aaaaatccgg gatatcatag aaaaaaaccg
     3481 gtatttcgag aaccttgaga ccaccatcac gtgcagggac ggatcggaaa aagtcatgct
     3541 ctggaacacc cgctccctct tcgcgggtga aaagggagaa aaagaagtat tcgttgcaat
     3601 cgggacggac atcacggcca tcaggcgtgc cgaggaagaa gtgcgggaat caaagaagtt
     3661 cctcgaggag atcctcaaca cgatcaatgt ccgggtcttt tggaaagatc ggaaccttgt
     3721 ctacatgggg tgcaaccggt catttgcccg cgatgcaggg tatgacaggc cggaggatgt
     3781 catcgggaag gatgatttcc agatgccctg gaaagacctg gccgaacgct acagggcgga
     3841 tgaccgcatc gtcatcgaga ccggttctcc cagaatgacg tacgaggagc cgctcacgac
     3901 ccctgccgga gagacactat ccctccttac gtcaaaggtc cccctctctg acctgaaagg
     3961 gaatacgatc ggtgtccttg gagtctatgt cgatatatca gacctcaaaa aggcagaaag
     4021 ggcattgaaa gagagcctga acaggacgga agcgatattg aaagccctcc cggacctcct
     4081 gtttgtcata tcgtccgatg ggattttcca cgaattccac tgtgccgacg agggggtgct
     4141 cgttcattcc cccggcgagt atgtcggaaa aagcatctgg agtttcgggt atcccaaaga
     4201 atccggagac gaattcatcc ggcacgtgaa aaccgcaata gagacgggaa agatccagta
     4261 tttcagttac gatctcacga tccgcggtaa aaaacgatac ttcgaggccc gcatcgccgc
     4321 ccttaacgaa gacagggccc tcgtgattgc cagggatatc acggaccgcg tcgagaggga
     4381 gcgcatgcag gaaaggttca cgagcgagct cgaggagcag gtccgtcaca ggacagagtc
     4441 cctcgaggca gctctccacg agaaggaact cctcctccgg gagatccacc acagggtcaa
     4501 gaacaacctc caggtcatca tcagccttat caacctccag gtgcgcatta cggaaaagtc
     4561 cggggcgacg gatatcctgc tcgataccca gaacaggatc agggccatgg ccctcgttca
     4621 cgaaaagctc taccagtcag gtgacctctc ccgcatcaac atcgcatcat atctcaggtc
     4681 ccttataagc caggtgtcgg catactatgg gacaaaaaaa cagaaagtga cattatcgat
     4741 cgcttgcgaa agtctctcca tggatatcaa ccgggcaatc ccgctcgggc tgatcatcaa
     4801 cgagcttgca agcaactccc tgaagcatgc gttccccggc gacagggagg ggaccgtgac
     4861 catccgggtt gagaggagag atgatcggat cgaatgcacc gtatccgatg atggtgtcgg
     4921 actcccgccg ggatttacca tcgaggagag tggttccctc gggctccgcc tcgtggcaac
     4981 cctggcaaaa cagttgcacg gcgggatcga gaggatacca acggagaagg ggacgatgtt
     5041 ccgacttgtc attcccggag gagaagaatg agaggtattc agcacagggt gcggatcctc
     5101 attgttgaag acgagcagat cgttgcagag gacctccggc agacccttga aaacatgggg
     5161 tattccgttg tcggggttgt aagcagcggg gagggtgcgg tggagactgc ccataaggag
     5221 attccggacc tcatcctcat ggacattatg ctgtccggga agatggatgg gatatcggcg
     5281 gcgcaccaga tacggagtga acacgatatt cccgtcattt acgttactgc atacgcagac
     5341 tcccagctca tcgaaagggc aaaggttaca gagccctttg gctacatcgt caaaccattc
     5401 aacgagcggg aattccagtc caacatcgag attgctctct ttaagcaccg gctcgagaag
     5461 gagatcagga agagagacgc gatccttctt gcactcggtt tcggtgtgga atggttcctg
     5521 cgccaggtat acgaggccca cggggccttg ctgagcggat cacccgtgac tttcgggtac
     5581 catctcgaac cgatcctcga gcatgtcgg
//
LOCUS       DAOOJU010000055         5561 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_11756_length_5561_cov_7.946240, whole genome shotgun sequence.
ACCESSION   DAOOJU010000055 DAOOJU010000000
VERSION     DAOOJU010000055.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5561)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5561)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5561
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11756_length_5561_cov_7.946240"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..4433)
                     /locus_tag="PK679_08905"
     CDS             complement(<1..4433)
                     /locus_tag="PK679_08905"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC56109.1"
                     /translation="MKKGFQHVQPGGIVALYRNICLKDDPSLVLPRINAHSLSFAMVS
                     FILLLLSVCFFIASPTTADSYVGGIPLVTVQSGTVTGDLWMDIAPAPDWGSTNVVKTF
                     SLPAEAVGNITWARLYVSAYCGHMQNNYAFSITNRFDGNGDGTYEKTWAEPATSSPSV
                     SLPVSFTYMDNGGNDNSAFPGHGTGEPYKMINDHMNRVTSDYFMWYDVTNMISSPTVN
                     VNVVTTGSSDGRIKVISLLVAYDQPGSNTKTLYWVNQGHDVCSYYTEDNYGEAAVGST
                     TFGTAGISDVDSATLYIEYLASNNGNYGFPTADNTFAYTGGTPPVEGSFTHPLDRDPD
                     VQGPYSGVDSWDVTSDLTGNDVTFAYARYFPGTGTAAFYKIPLAILVAKRQNQQDAPV
                     AAFTATPTSGNSPLEVSFTDQSTGTITSWAWDFDSDGTVDSTDQNPVHTYQTAGTYTV
                     TLTVTGAGGSDSEVKTSYITAKCNLVIQGVLNPRASNVFAFEPNTLQISNVRNTVGNS
                     PETEIEVTASDGWTGRVTVAPMNATGSQTVTIIDPTIRTAEGTVTYTYRIDPDNLVPE
                     TDETANQNKTIDKPVRFNGYKSTDYWAGKERVRTYLVFDIRGDIIHSFGDSKYKSGSF
                     GSGWYNDTATWTAGDLPVPDGAGIVAARLYIPYCWDHENEVGGGTTTTTFNGVTVSPA
                     HWEEDTSNFGAYADYRYGLLTYNVTGLYRKNEINTATFTRSIFSGKLSPAGFTLAVVY
                     ADPNASRKQIFVNEGWDLLGASEGDYATNETEAAAFQAFSGMTIDMAHADVANLTTFV
                     PWGAPQKEGDPGEGNLFVNGVQVGTNVWNYGERAVGESDSPQVAVDTRDILAYLNPSG
                     SGNSIAIQSTTGGSPSMVAERSFLVVEYHDDLPVADFSANVTSGQAPLVVQFTDASTG
                     YVTSYEWDLDGDGVTDSTDKNPVWIYSSPGTYSVRLTVTNSAGSDTKEKSSYITSGGT
                     GSPDLVITSITTNADELFASEPNAISATVLNNGTGAAGPFSVRFNVSGALYTASLPGL
                     AAGANGTATITDTILRTAGDTVMITAEADPDGDIPEIDRTNNGADLTRVVANNGYKGK
                     RYTGGSDIGTVATFEGRINLAVSTGDSAYRSTGWTGSATNWTVSDLHIPENATILHAR
                     LYQGYTFDQTPGGKPSWTARFNDETITPDVTYTDRKGYGTYNYPSGVFVYNVTPFFSK
                     SGNHLVVTAEEGNSNGLYGSLLLVVYADEREPQRKVLINEECDLLYAGTSRFVSDEEA
                     TSYIPFQGASGDGLQEARVIAFLYSANEAGKSAFIFNGNSHGDLSGGFEAGSQVTLKE
                     FNVTGDMAGGDNTALYRSVMVSGSGDNMVAAGAVLVLGYAEEPPAADFSASPLTGTAP
                     LSVQFTDLSTGNITARTWQYRSGNGTWTQFSTESNPAFSFSDPGTYDIRLTVSGPGGD
                     NTKERTGYITVLSQPGPTADFSASPLTGTAPLSVQFTDLSTG"
     gene            complement(4706..>5561)
                     /locus_tag="PK679_08910"
     CDS             complement(4706..>5561)
                     /locus_tag="PK679_08910"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC56110.1"
                     /translation="TGPSGSDSEVKTNYITVTVPVKPVAAFSATPTSGYSPLTVQFTD
                     HSLNYPNSWKWEYRKNPGTWVQFSTAQNPSFTFNETGFYSIRLTVTNAAGSNTVTRMN
                     YIIVTRLPKPVANFVASPTSGLSPLTVQFTDASMNNPVTWKWEYRKGSGTWVQFSTVQ
                     NPSFTFNETGFYSIRLTVTNAAGGNTVTKANYITVNPVRKPVALFSQDKVFGRAPLTV
                     SFRDRSLYNPTEYLWTFGDGTTSTEQNPVHTYTRSGLFTVQLSVSNAAGSDTARGIVF
                     VLNTRGLW"
BASE COUNT         1102 a         1456 c         1713 g         1290 t
ORIGIN      
        1 ccggtggaga ggtcggtgaa ctggacggag agcggcgcgg tgccggtcag gggtgatgcc
       61 gagaagtctg cagtcggtcc tggctgggag agcacggtga tgtatccggt tctctccttt
      121 gtattatctc caccgggtcc ggagacagtg agccggatat cataggtccc ggggtcggag
      181 aaggagaatg cgggattgga ttcggtggag aactgggtcc atgtaccatt ccccgaccgg
      241 tattgccagg tccgtgcggt aatgttcccg gtggagaggt cggtaaactg gacggagagc
      301 ggcgcggtgc cggtcagggg tgatgccgag aaatctgctg ccgggggttc ttccgcgtat
      361 ccaaggacca aaacagcccc ggcggcgacc atgttgtcac cgcttcctga taccatcacg
      421 ctccggtaga gggccgtgtt gtcgccacca gccatgtcac cggtgacgtt gaactctttc
      481 agcgtcacct gggaccccgc ctcgaaacct cccgagaggt caccatgtga attgccgttg
      541 aaaatgaacg cactcttgcc tgcctcgttt gccgagtaga ggaatgcaat aacccttgct
      601 tcctgcaggc cgtcaccgga agcgccctgg aacgggatgt acgatgttgc ctcctcgtcg
      661 gagacgaacc gggacgtccc ggcatacagg aggtcgcatt cctcgttgat caggaccttc
      721 ctttggggct ctctctcatc ggcatagacc acgaggagga ggctcccgta gaggccgttc
      781 gaattcccct cctccgcggt cacgacgaga tggttccctg attttgaaaa gaacggcgtc
      841 acgttgtaga caaacacgcc cgaggggtag ttgtaggtcc cgtatccctt cctgtcggta
      901 tatgtcacgt ccggtgtaat ggtctcatcg ttgaagcggg cggtccagga gggtttgcct
      961 cccggcgtct ggtcaaacgt atatccctgg tagagccgtg catggaggat ggttgcattt
     1021 tcagggatgt gcaggtcgga aacagtccag ttcgtggcag atccggtcca tcctgtcgat
     1081 cggtacgccg agtctccggt cgacaccgcg aggttaatcc ggccttcgaa ggttgcaacc
     1141 gtgccgatgt cgcttccccc cgtatacctc ttgcccttgt acccgttgtt cgcaacgact
     1201 ctcgtcaggt cagcgccgtt attggttctg tcaatttcag ggatatcacc gtcagggtct
     1261 gcctcggcgg taatcataac ggtatctcct gccgtcctga gaattgtatc ggtgatagtt
     1321 gcagtcccgt tggccccggc tgcaagaccg ggaagggatg cagtgtacag ggctccggac
     1381 acgttgaacc ggactgaaaa cggaccagca gccccggtcc cgttgttaag gacggtggca
     1441 ctgatcgcat tgggttcgct cgcgaagagc tcatcggcat ttgttgtaat actggtaatc
     1501 acgaggtcag gagaaccggt cccccccgat gtgatataac tgctcttttc tttcgtatca
     1561 ctgcccgcgg aatttgtaac ggtaagcctg acggaatagg tgccgggaga tgagtagatc
     1621 cagacagggt tcttatcagt actgtctgtg acgccgtcgc cgtcgaggtc ccattcgtag
     1681 gaggttacgt acccggtcga ggcgtcagtg aactggacaa cgaggggtgc ctgaccggac
     1741 gttacgtttg ctgaaaagtc agcgactggc aggtcgtcgt ggtattcaac gacgaggaaa
     1801 gaccgttcag cgaccatgga gggggaaccg ccggtcgtgg actggatggc tatactgttt
     1861 ccgctcccgg acgggttgag gtacgcgagg atgtccctcg tatcgacagc aacctggggg
     1921 gaatcgctct cccccacggc ccgttcgcca tagttccaga cattggtccc gacctggacc
     1981 ccgttgacga aaaggttccc ctcgcccgga tcaccttctt tctggggagc accccagggt
     2041 acgaacgttg tgaggttggc gacatctgca tgagccatgt cgatggtcat gccggaaaaa
     2101 gcctggaatg cggcggcctc agtctcgttg gtggcatagt cgccctcgct tgccccgagc
     2161 aggtcccacc cctcgttaac gaatatctgc tttctgctgg cgttgggatc ggcgtatacg
     2221 actgcaagtg taaagcctgc aggagagagt ttcccggaaa agatcgatct cgtgaaagtc
     2281 gcggtattga tttcgttctt cctgtagagg cctgtgacgt tgtaggtgag gagtccgtac
     2341 cggtagtcgg cataggcacc gaagttggag gtatcctcct cccagtgggc aggactaaca
     2401 gtcacaccgt tgaaggttgt ggtcgtcgtc ccgcccccga cctcgttctc atggtcccag
     2461 cagtagggga tgtagagccg tgcggcaacg atgcctgctc catcgggaac gggcagatcc
     2521 ccggcggtcc aggtggcggt atcgttgtac cagccgctgc cgaaactgcc ggacttgtac
     2581 ttgctgtcgc cgaacgagtg gatgatgtcg cccctgatgt caaacacgag gtaagtcctg
     2641 acgcgttcct tgccggccca gtagtcggta ctcttatatc cgttgaacct gacgggcttg
     2701 tcaattgtct tattctggtt cgcagtctcg tcggtctcgg gcaccaggtt gtccgggtcg
     2761 atcctgtaag tgtaggtaac ggttccttct gccgtgcgaa tggttggatc gatgatcgtg
     2821 acggtttgtg agcctgtcgc gttcatggga gcgaccgtaa ccctgccggt ccatccgtca
     2881 cttgccgtga cttcgatttc ggtctccggg gaattcccca cggtattcct gacattgctg
     2941 atctggagcg tgttgggttc gaatgcaaac acgtttgacg cacggggatt gaggacaccc
     3001 tggatgacga ggttgcactt cgccgtgata taggatgtct tgacctcgct gtcactcccc
     3061 cccgcgccgg tgaccgtcag ggtgacggta taggttccgg ctgtctggta agtatggacg
     3121 gggttctggt cggtgctgtc gacggtgccg tcgctgtcga agtcccaggc ccatgacgtg
     3181 atggtaccgg tggactggtc cgtgaaggac acttcgagcg gcgagttccc ggaggttggc
     3241 gtcgcggtga acgcagcaac cggagcatcc tgctgattct gtctctttgc gaccaggatg
     3301 gcgagcggga tcttgtagaa cgcggcggtt cctgttcccg ggaagtaccg ggcataggcg
     3361 aacgtgacgt cgttacccgt aaggtcagac gtcacgtccc aggaatcgac gccggagtag
     3421 gggccctgga catcagggtc gcggtcgagc gggtgggtga aactgccttc gaccgggggg
     3481 gtgcccccgg tatacgcgaa ggtattgtca gccgtgggga acccgtagtt cccgttgttg
     3541 ctcgctaagt actcgatata cagggttgcc gaatcgacat cggaaatccc ggcggtcccg
     3601 aaggtggtgg aaccgacggc agcttctcca tagttatcct cggtgtagta ggaacagacg
     3661 tcgtggccct ggttgaccca gtacagggtc tttgtattcg agccgggctg gtcgtaggca
     3721 acgaggagac tgatcacctt gatcctgccg tcggacgaac ccgtcgtgac gacgttgacg
     3781 ttcaccgtcg ggctggagat catgttcgtg acgtcgtacc acatgaagta gtcgctcgtg
     3841 actcggttca tgtggtcgtt gatcatcttg tacggctcac cggttccatg gccggggaaa
     3901 gcgctgttgt cgttgccacc gttgtccatg taggtgaacg agaccgggag ggagacagag
     3961 ggcgaggatg tcgcgggctc ggcccaggtc ttctcgtagg ttccgtcacc gtttccatcg
     4021 aacctgttgg tgatggagaa cgcgtagttg ttctgcatgt gcccgcaata cgcggagacg
     4081 tagagccggg cccaggtgat gttccccact gcctctgccg gcagcgagaa tgtcttgacc
     4141 acgtttgtgc tgccccagtc cggcgcgggg gcgatgtcca tccagaggtc gccggtcacg
     4201 gtcccggact gcaccgtgac gagcgggatg ccgccgacgt aactatcagc ggtcgttggc
     4261 gatgcgatga aaaaacagac cgaaaggaga aggagaataa aagaaaccat ggcgaatgaa
     4321 agggaatggg cgtttatacg gggcaggacc aatgacggat cgtctttgag acagatgttc
     4381 cggtataatg caacaatccc gccgggctgc acgtgctgga aacctttctt cattgggaac
     4441 accatgagat atcggacagg ctctttattg ctgatcggat ttttatgtac tataatttat
     4501 gataaaaaat aattttgtga tccttatttt aataaatacc aaacattctc atcatttttc
     4561 aaccatataa tccctttttt tttaaccgga aacggcagga tgttgaccat ggagcgatgc
     4621 gctggcgctg attcccctaa aaagcatgtc ccagagtggg aaaagaccgt tatcttttcg
     4681 gaaaagagag aaaaagggat ttttctcacc ataaccccct ggtattcagg acaaagacaa
     4741 ttcctctggc cgtgtcactg cctgcggcgt tcgatacact gagctggaca gtaaagagac
     4801 cggaacgggt ataggtatgg accgggttct gctcggtgga cgtggtcccg tctccaaatg
     4861 tccagagata ctccgttgga ttatagaggg agcggtccct gaatgatacg gtcagtggtg
     4921 ctcttccgaa taccttgtcc tgggagaaga gtgcaactgg ttttcgaaca ggattgaccg
     4981 tgatatagtt cgccttggta actgtattac ccccggctgc attggtcacc gtgaggcgga
     5041 tactgtagaa ccctgtctca ttgaaggtga acgaggggtt ctgcacggtc gagaactgga
     5101 cccaggtgcc cgaacccttc ctgtattccc acttccaagt cacggggtta ttcatggagg
     5161 catccgtgaa ctgcacagtc agtggcgata aaccgctcgt ggggcttgcg acgaagtttg
     5221 ccaccggctt gggcagtctg gtgacgatga tataattcat cctggtaact gtattactcc
     5281 cggccgcatt ggtcaccgtg aggcggatac tgtagaaccc tgtctcattg aaggtgaacg
     5341 aggggttctg cgcggtcgag aactggaccc aggtgcccgg attctttcgg tactcccatt
     5401 tccacgagtt cgggtagttt agggaatgat cggtaaactg gactgtcagc ggcgagtaac
     5461 ccgatgtcgg ggtggcactg aaggcagcga ccggtttgac cggcaccgtc accgtgatgt
     5521 agttcgtttt cacctcggag tccgagccgg agggaccggt g
//
LOCUS       DAOOJU010000056         5519 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_11861_length_5519_cov_14.614202, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000056 DAOOJU010000000
VERSION     DAOOJU010000056.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5519)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5519)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5519
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_11861_length_5519_cov_14.614202"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            242..1387
                     /locus_tag="PK679_08915"
     CDS             242..1387
                     /locus_tag="PK679_08915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KamA family radical SAM protein"
                     /protein_id="HPC56111.1"
                     /translation="MNPKYIHSIDELDNLVGLTPKERQEMECVTRKFPFRANSYYLSL
                     IDWKDRHDPLRRIVIPDLRELKDGGSLDPSNEKNYTKMPGLQHKYPQTALLLLSDVCG
                     GICRFCFRKRLFLTCKRETVRDISHGLEYIRSHPRITNVLLSGGDPFILETGQIESVL
                     RELREIQHVHAIRIGSKMLAYNPYRFLNDPHLIPMLSRFSTPEKRIYIVAHFNHPREL
                     TPASLEAIDRLLCSGIIVLNQTPLLRGVNSNPGVLTSLQRALTAAGVAPYYIFQCRPS
                     IGNSHFQVPVEQSYDIIQESWKACSGLAKRARYIMSHATGKIEVIGRTKKHIFMRYHQ
                     AADPDNVGKTMVFSSNPGAYWLDQYRSPVNPSEGIMALKMPKMHWLF"
     gene            1600..2982
                     /locus_tag="PK679_08920"
     CDS             1600..2982
                     /locus_tag="PK679_08920"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56112.1"
                     /translation="MTIEKRDHSMGFSWQGSQCLEKKPIVHIALIALSTVFVIFITFV
                     ALSLGIPAIFQNIYYIPIILACYYCRRKGLYFSILLVSFYFFSLLAYFPSFEIFFQGF
                     IRVLFFLLVAGIVTYLSETITREKARYQGIFSGSESGILLWERDTGRITEANPQASRI
                     SGYSDVELVRMTISDLFPDRALVETVLSEKEEPIRHREAEIRHSDGTRRIVTFSSAWI
                     DAATGMVTFQDITEKKRAEEAISLSNRKLNLLNSITRHDILNTMTALLGYLEISREIA
                     RDDELKKYIDSATRAAAVIRRQVEFSRDYQDVGVKSPAWFSLRDLIEKQKQHIEGAGI
                     RVEADLPDIRIYADPLIEKVFYNLMENSVRHGGNVSRVWFSTELGDGDLVIRCCDDGK
                     GIPDDKKDAIFNREYFQHSGFGLFLSREILAITGIRIRETGTFGQGAVFEIVVPAGSY
                     RISGTAKRTT"
     gene            complement(3074..3283)
                     /locus_tag="PK679_08925"
     CDS             complement(3074..3283)
                     /locus_tag="PK679_08925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56113.1"
                     /translation="MMDMCRDIVYRREGSRYTCIRKTGDGREEILFTGTPGEIREALV
                     AAGYPPISPELFLENLEEWTAGSGD"
     gene            3399..3857
                     /locus_tag="PK679_08930"
     CDS             3399..3857
                     /locus_tag="PK679_08930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56114.1"
                     /translation="MEDPTVFVRTMPNVYYRHTTGDTTPDMETRRRSGSRRTEIHAME
                     EKRGHFEKGAWVEEKDEGPANAGTRAMTDHDPMEKRVREVSSLVSTSFSELIALARDL
                     VATPEGHAHIRSHIEKVSSEIERSLSHLLENEGEKTGTGSSQKGEGPRRE"
     gene            4040..4762
                     /locus_tag="PK679_08935"
     CDS             4040..4762
                     /locus_tag="PK679_08935"
                     /inference="COORDINATES: protein motif:HMM:NF025973.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative dsRNA-binding protein"
                     /protein_id="HPC56115.1"
                     /translation="MTEKREEDSYRERLRVFLGDPRIGVTDPSPAALARYTAAFTHKS
                     FAREHGSAGVPVADYEALEFLGDRVLNLVVAEYIFRHSPGNEGEMTEKMEFARNSHLF
                     SIVSSLGTGFSGMIRLGSHQKLTSRIAASAFESFLGAYFLDRGFEKTRSFLLGLLGDE
                     LGTFIPFMNYKKRLQEHIQKTSRQIPVYERIAKEGPDHAPVFTYRVSVSGVILGTGKG
                     ITKTQATQEAARNALCSLGLLQ"
     gene            4877..5317
                     /locus_tag="PK679_08940"
     CDS             4877..5317
                     /locus_tag="PK679_08940"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HPC56116.1"
                     /translation="MTRRVLAAVDGSILTHNVIQTAIEEAMCRKAELHIVHVIEKEWT
                     DPDTAVELAIRDEEEEAASLLSSMKAEVEACGVAAVAHLLRGHPGDRIVDCAIDLDAE
                     LVVLGSVGKSQIKRMISGSVSSFVVTHCPVTTMVVKPGHKQHTG"
BASE COUNT         1363 a         1489 c         1450 g         1217 t
ORIGIN      
        1 ttagtgagaa tccgcttaaa gattaccctg cacggggaga ggaacgggac aggggtttgc
       61 cggaatcgtc tttttccggt gacctcatgg agaaagggtt tataccatga gcaggaaggt
      121 atgtttgcag gtcgccgcac agagaaagtg attttgcttt atttgggatt attcctttcg
      181 cggcagaccg atctgccatc cagaaatggc agaacaccca tgcaaaaaca gaggtgacga
      241 gatgaacccg aaatatatcc atagcattga cgagcttgac aacctcgtcg ggctcacacc
      301 caaggagagg caggagatgg agtgtgtcac ccggaagttt ccattccggg cgaacagcta
      361 ctacctctcc ctcatcgact ggaaggacag gcatgacccc ctccgccgga tagttattcc
      421 tgacctgcgg gaactgaagg atggtgggag ccttgatcct tcaaacgaga agaattatac
      481 gaagatgccc ggattgcagc acaagtaccc ccagaccgca cttctcctcc tgtcggatgt
      541 ctgtggcggc atttgcaggt tctgtttcag gaagaggctt tttctgacat gcaagaggga
      601 aactgtcagg gacatatcac acggtcttga atatatccgg tcccaccccc ggattacgaa
      661 tgtcctcctt tccggtggtg accctttcat cctggaaacg gggcagatag agtcagttct
      721 ccgcgaactc cgggagatac aacacgttca tgctatccgt atcggaagca agatgctcgc
      781 atataaccca tacaggttcc tcaatgaccc gcatctcata cccatgctct cccggttcag
      841 cacacctgaa aaaaggatct atatcgtagc ccatttcaac catccaagag aacttacccc
      901 ggcttccctg gaggccattg accggcttct ctgctcaggc atcattgtcc tgaaccagac
      961 acctctcctc cggggagtca acagcaaccc cggggtcctg acttccctcc agcgggccct
     1021 gaccgctgcc ggagtcgctc cctattacat ttttcagtgc agaccgtcca tcgggaacag
     1081 ccatttccag gtccccgtcg aacagtcata cgatatcatc caggaatcat ggaaagcttg
     1141 ttccggactt gcaaagcgtg cccggtacat catgtctcat gccacgggaa agatcgaggt
     1201 tattggaaga accaaaaagc acatattcat gaggtaccac caggcagcag accccgacaa
     1261 tgtcggaaaa acgatggtct tttcgagcaa tcccggggcc tactggcttg atcaataccg
     1321 gtcacccgta aatccttccg aaggtatcat ggccctgaag atgccaaaga tgcactggtt
     1381 gttttaaaaa tttccaccat tttttctcat atccgggaaa aagttcagcc tgacaggtgg
     1441 aacgggactt ttaagacatt tcccatagga tccaagataa ttggactatg aacgcagcaa
     1501 tcagaccccc ggatctccgt gtttcactga aagaatagaa tgagccgggt atttttaaaa
     1561 gagaggtttt ccggtccata ggattaaata atcaatcggg tgactattga aaagagggac
     1621 cactcaatgg gtttttcctg gcagggcagc caatgccttg aaaaaaagcc aatcgtgcac
     1681 atcgccctca tcgcactttc cacggtcttt gtcatattca tcacgtttgt tgctctttcg
     1741 ctgggaatcc ctgcgatttt ccagaatata tactacatcc ccatcatcct cgcctgctat
     1801 tactgccgga gaaaagggct ttatttttcc attctcctcg tatccttcta cttcttctca
     1861 ctgctggctt attttccctc tttcgaaatc ttcttccagg gattcatcag ggttctcttc
     1921 ttcctcctcg ttgcggggat tgtcacttat ctctctgaaa ctatcacgag agagaaggcc
     1981 cggtaccagg gaattttttc cggttcggaa tccggaatcc tcctctggga acgggatacc
     2041 ggcaggataa cggaagcaaa ccctcaagca tccaggattt ccggatattc cgacgtcgag
     2101 ctggtccgga tgacaatttc tgacctgttt ccggaccggg cactggtcga aaccgtcctg
     2161 tcggaaaaag aggaacccat ccgccacagg gaggcagaaa tccggcatag tgacgggacc
     2221 cgccggattg ttaccttctc ttcggcctgg atcgatgctg ctacgggcat ggtcaccttc
     2281 caggacatca cggaaaagaa acgggctgaa gaggcaattt ccctctcgaa caggaaactc
     2341 aacctcctca acagcatcac gcgccacgat atcctcaata ccatgactgc actgctcgga
     2401 tatctcgaaa tctcaaggga gatcgcaagg gacgatgaat tgaaaaaata catcgattcc
     2461 gccacccggg ccgcagcagt aatccggagg caggtagagt tttcccgtga ctaccaggac
     2521 gtgggggtaa agtcaccggc ctggttctcc ctgcgggacc ttattgaaaa acagaaacag
     2581 catatcgaag gggcgggcat cagagttgag gcggatcttc ccgatatccg gatctatgcg
     2641 gacccgctca tcgagaaggt cttttacaac ctcatggaaa attccgttcg ccacggcggg
     2701 aatgtcagcc gggtatggtt tagcacggaa ctgggagatg gagacctcgt catcaggtgc
     2761 tgcgacgacg ggaaaggaat cccggatgac aagaaagatg cgatattcaa ccgggaatat
     2821 ttccagcatt caggtttcgg actgttcctg tcccgtgaaa tactcgcaat cacggggatc
     2881 cggatccggg agacaggaac attcgggcag ggggcggtct tcgaaatcgt tgtcccggcc
     2941 ggttcttaca ggatttccgg taccgcaaag aggacgacct gacatcagcc agaggagagg
     3001 actttgctcg ctttacaatc agggaattgt ctgccggacc aaacccgcac ggcaaagtcc
     3061 tgcattcagg tttttaatcc ccgctgcctg cggtccattc ttccaaattt tccaaaaaga
     3121 gctcagggga gatgggggga taccccgcgg ccacgagcgc ttcgcggatc tcgccgggag
     3181 ttcccgtaaa aagaatttcc tccctgccat cccctgtctt ccggatacac gtgtaacggg
     3241 aaccctccct ccgataaacg atatcgcggc acatatccat catgggagaa tcacgctcca
     3301 ctcccaaaaa aatgactgtc ggggaagagg gacacagtct gttccagaat atcatcccgt
     3361 gcttgtgaaa ttaccggatg actttttatt tgcggaaaat ggaagacccg acagtttttg
     3421 tccggacgat gccaaacgta tactaccggc ataccacggg ggataccacg ccggacatgg
     3481 aaacccgcag acgatccggc agccggagga cggagattca cgccatggaa gagaagagag
     3541 gtcattttga gaagggtgca tgggtcgagg aaaaggacga gggcccggca aatgccggta
     3601 cccgtgccat gacagatcac gatccgatgg agaaacgggt cagggaggtc tcatccctcg
     3661 tttcgacatc tttttccgag ctcatcgccc tggcacgtga tctggtcgca acaccggaag
     3721 gccatgcaca tatcaggagc cacatagaaa aagtgtcgtc cgagatagaa aggtcgctct
     3781 cccatctcct cgaaaacgaa ggagagaaaa ccggaaccgg gtcgtcccaa aagggggaag
     3841 ggccccgcag ggaatgaccc ttttcccccg caaaagggaa tattccgcat ttcccaaaaa
     3901 acatggtgat catcgggaca cgggtcgata ggatgaaaat ggcggagccg ttgtcatcat
     3961 ccccacccgt gaccgccgtg ccgtcgcgca tgcagtccgg acatcgcgaa gcgattttcc
     4021 cgggaaaagg ggttgcagga tgacggaaaa acgggaagag gattcctacc gggaacgact
     4081 ccgggtattt ctcggcgatc cgcggatcgg ggtgactgat ccctcgccgg cagcactggc
     4141 ccggtataca gccgcgttca cgcacaaatc gtttgcaagg gaacacggtt ccgccggagt
     4201 tcctgttgca gactacgaag ctctcgagtt tctgggtgac agggtattga acctcgttgt
     4261 tgctgaatac atattccggc attcccccgg aaacgagggt gagatgacgg aaaaaatgga
     4321 atttgccagg aacagccacc ttttctccat cgtctcatcc ctgggaaccg gcttttccgg
     4381 tatgattcgg cttggctcgc accagaagct gacgtcccgg atcgctgcct ctgcattcga
     4441 gtcttttctg ggtgcttatt ttctcgacag gggatttgaa aaaacccggt cgttccttct
     4501 cgggttgctc ggcgatgaac tcggcacttt cattcctttc atgaattaca agaagagact
     4561 ccaggagcac atccagaaga catcccggca aatccccgtc tacgagagga tcgcgaagga
     4621 aggtccggac cacgcacccg ttttcaccta cagagtcagc gtttcgggtg tcatcctcgg
     4681 aacgggaaaa ggtatcacga aaactcaggc gacacaggaa gcggcccgga atgccctttg
     4741 ctcccttgga ctgcttcagt aggctgtccg gttccaaaaa agtcccggag gacttatctg
     4801 gtcctgtgtt cttactgata catgcataaa accccccggg attgacgggt gggccgaagg
     4861 aaaggagata tacgacgtga cacgccgggt tcttgctgcc gtggacgggt cgattctgac
     4921 tcacaacgtc attcagacag caatagagga ggccatgtgc aggaaggccg aactccatat
     4981 cgtgcacgtg atcgagaagg aatggacaga tcccgacacc gcagtggaac ttgcgatacg
     5041 ggacgaggaa gaggaggctg cgtccctcct ttcatcgatg aaggccgagg tggaggcttg
     5101 cggcgttgcg gcagtggccc acctcttgag gggacacccc ggcgacagga tcgtggattg
     5161 cgcgatcgat ctcgatgccg agctggtcgt cctcggttcg gtcggcaaga gccagataaa
     5221 gcgaatgatc tcggggagcg tctcatcctt tgttgtcaca cactgcccgg ttaccacgat
     5281 ggttgtcaag cccggccata agcagcatac cggttgaaat cctcgcctct tgcccgatcg
     5341 cttggaagga ctgattgccg ggatttttcc tatcgtcccc tgcatatgca ggaaactggt
     5401 atcttcaggg gtgaccctcc cctggcggga acaaaaacgg aaatctttct cccggggaac
     5461 cgcaatcgtg cggcattttt aacgtgatgg ggagaaaacc cagtacagga acttctgct
//
LOCUS       DAOOJU010000057         5447 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_12050_length_5447_cov_18.220141, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000057 DAOOJU010000000
VERSION     DAOOJU010000057.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5447)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5447)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5447
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12050_length_5447_cov_18.220141"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            333..539
                     /locus_tag="PK679_08945"
     CDS             333..539
                     /locus_tag="PK679_08945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56117.1"
                     /translation="MSPPSERSSAHCPVFGVASGAPIVGLGILIIIFGGVLLLTGHSP
                     DVTLPPALLFIGFGAVLIVLGIRR"
     gene            587..1186
                     /locus_tag="PK679_08950"
     CDS             587..1186
                     /locus_tag="PK679_08950"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HPC56118.1"
                     /translation="MTQDSGKKSSGGADHGALELLVEQATQSGDPHVRRYALFVLGRT
                     GDPRLKELFLSALRDTDKACRAQAAAALIGLGDTIVPDLVSLLSDADWRVRYRAAEAL
                     GEIGNRASAGALVRALSDKKDHVRYMAAKGLGRTGNSGAVPALVGCLEDENPYVRKAA
                     VLSLGKLGNSHIRDVVRKHLDREGTDFVREAIRNVLSGE"
     gene            complement(1430..3418)
                     /gene="metG"
                     /locus_tag="PK679_08955"
     CDS             complement(1430..3418)
                     /gene="metG"
                     /locus_tag="PK679_08955"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HPC56119.1"
                     /translation="MRKQPILVTCGLPYTNGPCHIGHLRTYVPADFYVRCLRHMGEEV
                     VFICGSDNHGTPIVVSAEEAKISPREMSERYHAHFAETFGRMMVQFDHFGMTDDPTNH
                     ARTRKIVSRLIENGHVYSRVIQQSYCPQCKRFLPDRYVEGLCPHCGTPARGDECDQGC
                     GRHLEPGEIREPVCMVCKTKAELRDQEHYFFRLGEFKDFLLGYLENLQGTLNARNYAL
                     GWVREGLRDWCITRTLDWGVKFPGRDDLVVYVWVDAPIGYISFTEEWANEAGKDWRDL
                     WCGDNRVTHFIGGDIIYHHCIFWPALLKGAGYGTPHAIVASGMVKVDDHKFSKSRGYV
                     VWTNEDYLDRGLPADYLRYYLLSYTNHTKDLNFSWKVFSERINNELVNTLGNFVYRSL
                     YFAHREFGGIPDIPVRPEVLARIKETIDSVTRAVNQYDFKVAVDEMMALAAYGNNYIQ
                     TNAPWKLIKTDRDSACQVIKDCIVLVNALALLFEPAIPQKSREIWDMVGNTVPIEKTA
                     LDSALGDLPARPLKAPHPVFQKLEDSFIREMDDLLRKRVKEAGERVRKTETVSIEEFS
                     RLDIRTGRIVSAEPVPKSQKLLTLQVDIGSEIRQVVAGIAPFYRPEDLVGKNVVIVAN
                     LQPARIFGIESRGMILAAGDSASLLMPFKDVPPGTKIR"
     gene            3462..4253
                     /locus_tag="PK679_08960"
     CDS             3462..4253
                     /locus_tag="PK679_08960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56120.1"
                     /translation="MGKKTVLKTCSLGAEPGVPSPGRLAEWAGEQRGRCADLTSFLVE
                     ESIIPQVDAGITTPCAGGKFYSARLQESIVGLEGDRIRGELAISPGFLIDDAARAGIR
                     AHPCRFAVPAPHLVVKGDEYYGDADEASGALYEQYRHIFRAMRDAGVNGHVCICERAV
                     PEEMEALAGRRVLFHIEKATTATLEEVLEYQQTLIIEGSGTREIGRLRDEFDVSNVLV
                     LDPKEDELRAAIEVFGPDRIQVAGYCANGDPDYWKSIVASAAVKI"
     gene            complement(4305..5273)
                     /locus_tag="PK679_08965"
     CDS             complement(4305..5273)
                     /locus_tag="PK679_08965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoesterase"
                     /protein_id="HPC56121.1"
                     /translation="MTFPWFSGRGKKRDEDLLLEGRERGVVHLTHNDLDAVGCDAIHR
                     RAFPHVTTIFCSVGRFPHVMETVSKVPGEGDTLSISDLGYYSGAESVLSRIRDNGWRV
                     EWRDHHRWRPEELGKCAASCDLLNVNVDTCATGICARDLLPHDPVAREIASVVCDYDL
                     WIHADPRSAILGQVLQRRENREHVRDCLVQGIFSDPTIEREYREIHEEMERLIKKSIR
                     KTQIEGKKYRIGFAPLFGYPSETAAAMRKALGTDMEVLISASGRFSLRSVPPVSHILA
                     RNFGGGGHPHAAGGNFPFGFWDKILFRLLGRCPHIRRFVETAESLP"
     gene            5373..5446
                     /locus_tag="PK679_08970"
     tRNA            5373..5446
                     /locus_tag="PK679_08970"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5407..5409,aa:Phe,seq:gaa)
BASE COUNT         1212 a         1455 c         1555 g         1225 t
ORIGIN      
        1 tgtgaggagg cgaacctgcg agagcctgaa aaccattcac tcatgagaca ccacttcaaa
       61 taatgaagag gggcactttc attggtgaat ctggaatagt tatgccgtat gtattccatt
      121 gcccctgaat tttttttcac atgggaacgt tgacagggaa tcatggacca tgcgatcacc
      181 ttaaaaggga aaggagagga gataaccggc ggatcgggtt tgtaaactct atcatgctat
      241 acctccgatg tgatgaagat gagaacgtgg tcctttattg acacggagga cttagtcgga
      301 ttgctgacag ggatatggag ccggaaagaa gaatgtctcc accatcggaa cggtcaagtg
      361 cccattgccc ggtttttggt gttgcttccg gagccccgat cgtcgggctt ggcatcctca
      421 tcatcatttt tggaggagtc ctcctgctga cagggcactc tcccgatgta actcttcccc
      481 ctgctctgct gttcatcggg tttggtgcag ttctcatcgt tctcggcatc aggagatgat
      541 gcaaaaaccg tatgcaggag aagatctcaa ccactcaggg gagaaaatga cacaggattc
      601 cggaaaaaaa tcatcaggcg gtgcagacca tggagcactc gaactgctcg ttgaacaggc
      661 gacgcagtct ggggatccgc acgtcaggcg gtatgcactc ttcgttctcg ggaggacagg
      721 agatccccgg ctgaaagaac tttttttgtc agccctccgg gacacagaca aggcctgccg
      781 ggcccaggca gccgctgccc tcataggcct tggagatact atcgttcctg atctcgtctc
      841 cctgctttcc gatgcggact ggagggtccg gtacagggcc gcagaggcac tcggagagat
      901 cgggaaccgc gcatcagccg gggcacttgt cagggcatta tcggataaaa aggaccatgt
      961 caggtatatg gctgcaaagg gactcgggag aaccggcaac agcggggcag ttccggctct
     1021 cgtgggatgc cttgaggatg aaaaccccta tgtccggaaa gctgcagtcc tctccctcgg
     1081 aaaactgggt aactctcata taagggatgt tgtcaggaag cacctggaca gggagggaac
     1141 ggatttcgtc agggaagcca tcaggaatgt cctttcaggg gagtgaaaaa tatccagtca
     1201 tcagaaagac acagggccaa tcgttcagga aaatgacaga gcaattatcc ctgatagagg
     1261 gcactctccc cccgaatttc agaactgatt ctttctttgt ggataacttt cccaaaatga
     1321 ggagtggtca catatcgcat gttgcatcgt gtgttcatgc ggtgatggtc tcacataatg
     1381 ttcgtggaca atctgaaaaa aaaattgaaa aggagacagg gcacctggat tacctgattt
     1441 ttgtcccggg cggcacgtct ttgaaaggca taaggaggga tgcagaatcc ccggcagcga
     1501 ggatcatccc cctgctctcg atcccaaaga tcctggccgg ctggaggttc gcaacgatca
     1561 ccacgttctt tcccaccaga tcttccggcc tgtagaaggg tgcgatcccg gcaacgacct
     1621 gccggatctc ggagccgata tcgacctgca atgtgaggag tttctgggat ttgggaaccg
     1681 gttcggcaga aacgatcctg cccgtccgga tgtcaaggcg ggagaattct tcgatggata
     1741 cggtctctgt tttcctgacg cgttcgccgg cctcctttac cctcttccgg aggaggtcat
     1801 ccatttcccg gatgaatgaa tcctcgagct tctggaagac cgggtgcgga gctttgagtg
     1861 gtcgtgcggg aagatcgccg agagcactgt caagggctgt tttttcaatc ggcacggtgt
     1921 ttcccaccat gtcccatatc tcgcgggact tctgcgggat agcaggttcg aaaaggaggg
     1981 ccagagcatt gacaaggacg atgcagtcct tgatgacctg gcacgcggaa tccctgtcgg
     2041 tcttgatcag tttccagggc gcatttgtct ggatatagtt atttccataa gctgcaagcg
     2101 ccatcatctc gtctaccgcg accttgaaat cgtactggtt cacggctctc gtgaccgaat
     2161 cgattgtttc ttttatccgc gcaagtactt cgggtctcac cggaatatcc gggattccgc
     2221 caaattcacg gtgagcaaag tagaggctgc gatagacaaa gttcccgagc gtgttgacaa
     2281 gctcgttgtt gatccgctcg gaaaagactt tccaggaaaa gttgaggtcc ttggtgtggt
     2341 tcgtgtagga gaggaggtag tagcggaggt agtcggcagg aaggccccgg tcgagatagt
     2401 cctcgttcgt ccagacaacg tacccgcggg acttggagaa cttatgatca tccaccttca
     2461 ccatcccgct tgcgacaatc gcatgtggtg ttccatatcc tgcccctttc aggagtgccg
     2521 gccagaagat gcaatgatgg tagatgatgt cgccgccgat gaaatgcgtc acgcggttat
     2581 ccccgcacca taagtctctc cagtctttcc ctgcctcatt ggcccattcc tcggtgaacg
     2641 aaatgtaccc gatgggtgca tcgacccaca cgtagacaac gagatcatcc cgtccgggaa
     2701 acttgacccc ccagtcgagg gttctcgtga tgcaccagtc gcgaagacct tccctgaccc
     2761 agccaagcgc atagttccgg gcgttcaggg ttccctggag attttcgagg taaccgagga
     2821 ggaagtcctt gaactccccg agacggaaga aatagtgttc ctggtcacgg agttccgcct
     2881 ttgtcttgca gaccatgcaa accggttccc tgatttcgcc tggttcgagg tgacgtccgc
     2941 acccctggtc acactcgtcg ccccgtgcag gtgtgccgca atggggacac agtccctcga
     3001 cgtaacggtc agggagaaat cgcttgcact gcgggcagta actctgctgg atgaccctgg
     3061 aatagacgtg cccgttctcg atgagtctgc tgacaatttt cctggtccgg gcatggttcg
     3121 tggggtcgtc tgtcatcccg aaatggtcga actggaccat catacgcccg aaagtttcag
     3181 caaaatgggc atggtagcgt tctgacatct cccggggaga gatctttgcc tcttccgcac
     3241 tgacaacgat gggtgtccca tggttgtcag atccgcagat gaagacgact tcctccccca
     3301 tatgccgcag gcagcggaca taaaagtctg cgggcacgta tgtccgcagg tgcccgatgt
     3361 gacaggggcc gttggtatag gggaggccgc aggtcacgag gatgggctgt tttctcatca
     3421 ttatgctttt gatggtgatg ctataaataa ctaaaaggac catgggcaaa aagaccgtcc
     3481 tgaagacgtg ttcgctcggt gcggaaccag gtgtgccatc tcccgggagg ctggcggagt
     3541 gggcaggaga gcagagaggg aggtgtgccg atctcacttc tttcctcgtg gaagagagca
     3601 tcatcccgca ggtggacgca ggaatcacaa ccccctgcgc aggggggaag ttctattcag
     3661 cacggctgca ggagtcgatc gtgggacttg aaggtgaccg gatccgcgga gaactcgcga
     3721 tttctcctgg ttttctcatc gatgatgcag caagggcagg catacgtgcc catccctgcc
     3781 ggttcgccgt ccctgcaccc cacctcgttg tgaagggcga tgagtattac ggggacgccg
     3841 acgaggccag cggcgccctc tatgaacaat accggcacat tttcagggcg atgagagatg
     3901 caggagtcaa cggtcatgtc tgtatctgtg aacgggcagt gccggaagag atggaagctc
     3961 tcgctgggag gcgggtgctt tttcacatcg aaaaagcgac tactgcgacg ctggaagagg
     4021 tcctcgaata ccagcagaca ctcattattg aagggtccgg cacccgggag attggcaggc
     4081 tccgcgacga gtttgatgtc tccaatgtac ttgtcctcga tccgaaggag gatgaactca
     4141 gggctgcaat agaggtattc gggccggacc ggattcaggt cgcgggttac tgtgccaatg
     4201 gagacccgga ttactggaaa tccatcgtgg cttctgcagc cgtgaagatc tgataaaccc
     4261 cgcgaaaccc cggttccata ccatttgttg acaatgggcc ccttttacgg cagggactcg
     4321 gcagtctcca cgaaccgcct gatatggggg caccgtccca aaaggcggaa gaggattttg
     4381 tcccagaaac cgaacggaaa gttcccgccc gcggcatggg ggtggcctcc acccccgaag
     4441 ttccgtgcaa gaatgtggct gacgggaggg actgaccgga gggagaaccg ccccgaggcc
     4501 gagatgagga cctccatatc cgttccaagc gcctttctca tcgcagcagc tgtctcgctc
     4561 gggtagccga agagtggtgc aaacccgata cggtatttct tcccctcgat ctgcgtcttc
     4621 ctgatgctct ttttaatcag cctttccatc tcctcgtgta tctccctgta ttcacgttct
     4681 atggttggat ccgagaagat gccctgcacc aggcagtccc tgacgtgctc ccggttctcc
     4741 cgcctctgga ggacctgccc gaggattgcc gaccggggat ctgcatggat ccagaggtca
     4801 taatcgcaga caacggatgc aatttcgcgg gcgacgggat catgagggag gaggtcacgg
     4861 gcacaaattc ctgtggcaca cgtatcaacg ttcacgttga ggagatcaca ggaggcagca
     4921 cacttcccca gttcttcggg acgccacctg tggtggtccc tccactctac cctccacccg
     4981 ttgtccctga ttcgcgagag aactgattca gccccggaat agtatccaag gtccgagata
     5041 ctgagcgtat ccccctctcc cgggactttc gagactgttt ccatgacatg ggggaaacgg
     5101 cccacggaac agaagatcgt tgtcacgtgg gggaatgccc tccggtgaat ggcatcgcac
     5161 cccacggcat cgaggtcgtt gtgcgtaagg tgaacgacac cccgctcccg gccttcgagg
     5221 aggaggtctt cgtctctctt cttcccgcgt ccggagaacc atggaaatgt caagggatgc
     5281 accgcctttt ctccacagga ttccgacctt cttttctttt catcccggaa aacacataat
     5341 ttattaggcg ggactgacaa tattgtttcc ctgcctcagt agctcagttc gggagagcgc
     5401 cagactgaag atctggttgt ccccggttca aatccgggct gaggcat
//
LOCUS       DAOOJU010000058         5292 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_12471_length_5292_cov_14.906435, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000058 DAOOJU010000000
VERSION     DAOOJU010000058.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 5292)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5292)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5292
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_12471_length_5292_cov_14.906435"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..330
                     /locus_tag="PK679_08975"
     CDS             <1..330
                     /locus_tag="PK679_08975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56122.1"
                     /translation="GLADSSCSPFPCDNTRSCGLYDCHPTGKLVPAFEALKKELISQY
                     GDTIEITLTLIDKEIPSRIRDIIAENYPPIPFVIINGNLVPMGRISLPLMQKEIEKRM
                     KGIMQPS"
     gene            complement(314..895)
                     /locus_tag="PK679_08980"
     CDS             complement(314..895)
                     /locus_tag="PK679_08980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011832640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HPC56123.1"
                     /translation="MIDKLLEGNRKFREGFFRENLEHYRELTKGQNPSVLWIGCSDSR
                     IQSGHITQAMPGTLFIHRNIGNIAPLHDWNFATVLEYAIRHLKVKDIVICGHSDCGAI
                     KALDKETTDVYIPLWLNNAVEAKKRVDARIPPPKTPEERKARSEMIEKENIMLQIEHL
                     KNYPLVKEALLEKKIQVHGLYYNLETGELTKVA"
     gene            1027..1833
                     /locus_tag="PK679_08985"
     CDS             1027..1833
                     /locus_tag="PK679_08985"
                     /EC_number="2.3.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015019 - heparan-alpha-glucosaminide
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0007041 - lysosomal transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heparan-alpha-glucosaminide N-acetyltransferase"
                     /protein_id="HPC56124.1"
                     /translation="MKEIMNFVLPWQKSGGRKAVSVPSGRFWEIDFLRGSAVVMMVVF
                     HTVFDLAYLGILDIRVSFGPWRFLALCTATLFLFLVGLSLTISSARAGDMLDRHAYIL
                     KFIRRGAGIFMLGLLITLVTLLLVPGAPILFGILHLIGVSVMLAPLYLPYTRANLVAG
                     LALIAAGAALRAVTGPEYLLWLGIHPAAFSSLDYTPLVPWLGVVLMGVFTGKILYPGG
                     KRKYNIPDLPFMGRKVICFLGRHSLIIYLLHQPAILLAIFLLWGIPGIRY"
     assembly_gap    2079..2178
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2179..3539)
                     /locus_tag="PK679_08990"
     CDS             complement(<2179..3539)
                     /locus_tag="PK679_08990"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56125.1"
                     /translation="MQEPAVLFQRTNARLFTLGAITLVAFVAYAWGLSGGLSVFTPLL
                     FYFPIILAAYWFPRQGVIFAVITGILEVFLVYLFSYPDLTEITFAVTTASFYVLVAVA
                     VVISSLSGEMRDREARYRGIFNSSEAGIFVVRNGARELIIEEANPRGSVILMEHPRDL
                     RGKKFTEFWKDESARKYFLGVLENDGTAPQYETSIARADGTTVPVLISGARLPGHMMV
                     LMVIDISARIAQEREIQTKNDQLELINRVTADASSASDIGWLMHSVLGHTRKFSGCDL
                     CGAYVFHEGQPPLLFVDGDSELLKLVESSDSEISLAWRDATTKGLPLRWNGDRKVPAG
                     LPLAGMVTPLASGDGIVGVLFFLSMKNVGAFPDQLAKSVASEIATAVTRIRLMERLAE
                     ANRQANLYLDILMHDINNANLASLWYGDLLLEMLSGEPRVVAGKLIDGIKKSREIIRN
                     VET"
     gene            complement(3650..5002)
                     /locus_tag="PK679_08995"
     CDS             complement(3650..5002)
                     /locus_tag="PK679_08995"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HPC56126.1"
                     /translation="MAAAHGNGKISVLFIDDEPALLEITKLFLERSGELRVETCRSAV
                     EALEVLKARSFDAIVCDYEMPLMDGIVLLKILRAEGDFTPFIIFTGKGREHVVVEALN
                     NRADFYLSKGQDPKAQFAELDRMIRQAISRRAAEESLHSADRQMVDIINHLPDATFAI
                     DREGRVISWNKAMEDLTGIPASEMIGKGNFEYAVPFYGKKRPLLVNLLNSPEAEVRAL
                     SYQNIQRDGNSLTAENPEAILRGRPAVLWSRATLILDRKGTTIGAIESVRDITDIREM
                     TEKQQAEISREKEIGLFDRIFGKSTASWFKRGVDLYYKQGRFIDAVECFDRVIEMDPA
                     HMEAWREKGICLKELGRYEEALQCFDRAIDLGGKVPATYYAKGETLERLGRETGDYSL
                     YERAIEYFDLVLQKEPDNVNAWNYRGVCLKELGRYEEARRSFDKAQTILRTDPRKLTR
                     "
BASE COUNT         1105 a         1444 c         1372 g         1271 t
ORIGIN      
        1 ggcctcgcgg actcttcgtg ttcaccgttt ccctgtgaca acacccggag ttgtggtctc
       61 tatgactgcc acccgacagg aaagctcgtc ccggcattcg aagcactgaa aaaggagctc
      121 atcagccagt acggggatac catagaaatc acgctgacac tgatagataa ggagatccct
      181 tcccgtatca gggacattat tgcagagaat tacccgccga tcccgttcgt gatcatcaac
      241 ggtaaccttg ttccgatggg aagaatttcc ctgcccctga tgcagaaaga gatagaaaag
      301 aggatgaaag gaatcatgca accttcgtga gctccccggt ttccaggtta taatagagtc
      361 catggacctg gattttcttt tcgaggagcg cttctttcac gagggggtaa ttcttcaggt
      421 gttcgatctg aagcatgata ttttcctttt caatcatctc tgatcgtgct ttcctctcct
      481 cgggtgtttt cgggggaggg atacgggcat caacgcgctt ctttgcctcg actgcattgt
      541 tgagccagag ggggatatac acgtctgtcg tctccttgtc aagtgccttg attgccccgc
      601 agtccgagtg accacagatc acgatgtcct tgaccttgag atgacggatg gcatattcga
      661 gaaccgtcgc aaagttccag tcgtgcaggg gagcgatgtt ccctatgttc cggtgtataa
      721 acagcgtccc gggcatggcc tgggtaatat gcccggattg gatccttgaa tccgaacacc
      781 ctatccagag cacggagggg ttctgcccct tcgtaagttc cctgtaatgt tccaggtttt
      841 ccctgaaaaa accctctctg aatttcctgt ttccttcgag gagcttgtca atcatggata
      901 atcacctctt ccgggtggaa tggcggacga ctcctgccct ttcatgcgga gaagctgtcc
      961 ctgcacaggg taccgtgcac agaaggtata aaggattgat atttgttctc cggggccaac
     1021 atagggatga aggaaataat gaattttgta cttccctggc agaagtcagg aggaaggaag
     1081 gcagtatcag tcccctccgg tcgtttttgg gagatcgatt tcctgcgggg gtctgctgtt
     1141 gtcatgatgg tggtgttcca caccgtgttc gatcttgcct atctgggaat tctcgatatc
     1201 cgggtctcgt ttggtccctg gaggttcctt gctctctgca ctgcgaccct tttcctcttc
     1261 ctcgtcgggc tctccctgac cataagcagc gcaagggcag gggacatgct cgacaggcat
     1321 gcgtatatac tcaagttcat caggaggggt gcgggtatct tcatgcttgg tctcctgata
     1381 acccttgtca ccctcctgct tgttcccggg gcacccatac tctttggaat cctccacctg
     1441 atcggggtct ctgtcatgct cgcacccctc taccttcctt atacgcgtgc gaacctggtt
     1501 gcaggtcttg cgttgatagc ggcaggcgca gcgttgcgcg cggtcaccgg gccggaatac
     1561 ctgctctggc ttggtatcca tccggctgct ttttcaagcc tcgattacac gccccttgta
     1621 ccatggctgg gtgtcgttct gatgggtgtc tttacgggaa agatccttta cccgggtgga
     1681 aagaggaaat acaacattcc cgacctccct ttcatgggaa ggaaagtgat ctgcttcctc
     1741 ggacggcatt ccctgatcat atacctgctg caccagcctg caattcttct cgcaattttc
     1801 cttctatggg gaatccccgg gatcaggtac taaaagagga aagaaagcgc cgggaaatgc
     1861 gggatgttat cggttatccg tgtcaccatc aggagtgcct taccggtctg taacctcgcg
     1921 aagggttatc cggaacgagg cgcccttcgc gtggtcaccc gcgatcctgt cggagacctc
     1981 gatgtcaccc ccgtaccggg agatgagtgc cttcacgata tagagtccaa gacccttgct
     2041 gtgttctccc ggttcgaacc gggcaaaacg cccaaagann nnnnnnnnnn nnnnnnnnnn
     2101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2161 nnnnnnnnnn nnnnnnnnat cgtttcgacg ttcctgataa tctcgcggct tttcttgatt
     2221 ccgtcgatca acttgccggc aacaacacgc ggctctccgg agagcatctc gaggaggaga
     2281 tcaccgtacc agagggaggc gaggtttgca ttgttgatgt cgtgcatcag gatatccagg
     2341 tacaggtttg cctgcctgtt ggcctccgcg agtctttcca taaggcggat cctcgttact
     2401 gccgttgcaa tctcactggc aacagacttt gccagctggt ccggaaacgc cccgacattt
     2461 ttcatcgaga ggaagaacag cacacccaca attccgtcgc cgctcgcaag gggtgttacc
     2521 attcccgcaa ggggcagacc cgccgggact ttccggtcgc cgttccaccg gaggggtaag
     2581 cctttcgtcg ttgcatctct ccatgccagc gagatttccg agtccgacga ttctacaagt
     2641 ttcaggagtt ctgaatcccc gtccacgaaa agcagcgggg gctgtccttc gtggaacaca
     2701 taagccccac agagatcgca gcccgaaaat tttctggtgt gtccaagcac agaatgcatc
     2761 agccatccga tatcggatgc agacgatgca tccgcagtta cccggttgat cagttcaagc
     2821 tggtcgttct tcgtctgtat ctctctctcc tgcgctatcc ttgcagagat gtcaatgacc
     2881 atgaggacca tcatgtgacc ggggagcctc gcgccagaga tcaggacagg gactgtcgtg
     2941 ccatcggccc ttgcaatcga tgtctcgtac tggggtgctg tcccgtcgtt ctccagcacc
     3001 ccgaggaaat atttccgggc agattcatcc ttccagaatt ccgtaaattt ttttccccgc
     3061 aggtcacggg gatgttccat caggatgaca ctcccgcggg gattcgcttc ctcgatgatg
     3121 agctcgcggg caccgttcct gacgacgaat atgccggctt ccgaactgtt gaagatcccc
     3181 ctgtatcggg cctccctgtc ccgcatctcc ccggacaggg atgaaatgac cacggcaaca
     3241 gcgacaagga cgtagaaact cgcggtcgtg acggcaaagg tgatctctgt caggtccggg
     3301 tacgagaaga ggtagaccag gaagacttcc aggatccccg tgataaccgc gaatatcacg
     3361 ccctgccggg gaaaccagta tgccgcaagg ataataggaa agtaaaagag gagcggggtg
     3421 aagaccgaga gaccgcctga caatccccag gcatacgcga cgaacgcaac gagggtgatt
     3481 gcaccaagag tgaaaaggcg ggcatttgtc ctctggaata gaaccgcggg ctcctgcatc
     3541 ctggcaccac tctgtgtctc atttgtttat ctttgaactc atttaaaaca tcggtgaaaa
     3601 gacccggtgt aaggaagact aaggaataga cacggtgaat gcctgtctgt taccgggtga
     3661 gtttccgggg atctgtccga agaatagtct gggccttgtc aaaggaacgc cttgcctcct
     3721 cgtatctccc cagctccttg agacagactc ccctgtaatt ccaggcgttc acgttgtcgg
     3781 gttccttctg gagaacgagg tcaaaatatt caatcgccct ttcgtagagt gaataatctc
     3841 ccgtctccct cccgagtctc tcgagggtct ctcccttggc gtaatacgtc gcagggacct
     3901 tcccaccaag gtcaatggcc ctgtcaaaac actggagcgc ctcctcgtac ctccccagtt
     3961 ccttgaggca tattcccttc tctctccatg cctccatgtg ggcggggtcc atctcgataa
     4021 cgcggtcaaa acactctacg gcatcgatga aacggccctg cttgtagtag aggtccaccc
     4081 ctctcttgaa ccagcttgcg gtcgatttcc cgaatatcct gtcgaagagc ccgatctcct
     4141 tttccctcga gatctcggcc tgctgttttt ctgtcatctc ccggatatcc gtaatatcgc
     4201 ggacggattc gattgccccg atagttgtcc ctttgcggtc cagtatcagg gttgcccttg
     4261 accagaggac tgccggacga ccccggagaa tcgcttccgg gttttcggcg gtgagtgaat
     4321 tcccgtccct ctggatgttc tggtaggaca gggccctgac ttccgcttcg ggactattga
     4381 ggaggttgac aaggaggggc cgcttctttc catagaaggg aaccgcatat tcgaaattac
     4441 cctttccgat catctctgaa gcagggatgc ccgtgaggtc ttccattgcc ttgttccagg
     4501 agatgacgcg tccctcgcga tcgatagcaa acgtcgcatc gggaaggtga ttgatgatat
     4561 cgaccatctg ccggtcggca ctatggagcg actcttcagc ggcccggcgg ctgatggcct
     4621 ggcggatcat ccggtcgagt tcggcgaact gggcttttgg atcctgtccc ttcgagaggt
     4681 agaaatcggc cctgttgttg agggcttcca caaccacgtg ctcccttcct tttcctgtga
     4741 agatgatgaa aggcgtaaag tccccctcgg cccggagtat cttgaggaga acgatgccgt
     4801 ccatcagggg catctcgtaa tcgcagacaa tggcgtcgaa gctccgtgct ttcagaacct
     4861 cgagggcttc gacggcagat cggcacgtct cgacccggag ctctcccgac cgttccagga
     4921 atagcttcgt gatctcgaga agggccggtt catcatcgat gaaaaggacc gagatctttc
     4981 cgttcccgtg agccgctgcc atttcctcaa gagattatct ctgctgttgt acttaaccct
     5041 ttcatcatcg gaaaaaggga gaaacgacag gaaaaaggga ggcaggggga atgtttgaat
     5101 agcactcttt gcactcctgc ccctttgcac ggagtcattc aacgcatatc tgtgacgcct
     5161 ttgtaataca acattaccct ttccattttc ctgaaaggaa ggcggggtca aataaggcgg
     5221 gcatatcaga ggaagagggg aacgtcccgg aactcccttg catcgaaaag acccctctcg
     5281 gttatcctga ga
//
LOCUS       DAOOJU010000059         4802 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_13983_length_4802_cov_15.556773, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000059 DAOOJU010000000
VERSION     DAOOJU010000059.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 4802)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4802)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4802
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_13983_length_4802_cov_15.556773"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(170..1201)
                     /gene="hypD"
                     /locus_tag="PK679_09000"
     CDS             complement(170..1201)
                     /gene="hypD"
                     /locus_tag="PK679_09000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HPC56127.1"
                     /translation="MVSVGREIAGKLKELVDRDLSFMHICGTHEAAISRAGLRRVLPQ
                     QMKIVMGPGCPVCITPQGEIDAALELAGRGFAIATYGDLLRVPGSRGSLESSGGDVHV
                     VQGVHRAVEIAKQTDKEVVFISVGFETTAPTVAATILSEPPENFSILSCHRLVPPAMK
                     WLLEQGEANLQGFLLPGHVCTVAGYKEYEQFPVPQVVAGFEPEDILLGLLMLVEQVRK
                     GEARVENAYPRAVTREGNVRAQQLMYEVFEPTDVEWRGFPVIPRSGLKLRKKFEEYDA
                     QKKFDIGFRPVTKHTACLCDRVLRGLVSPTDCRLFGTACTPRTPVGPCMVSHEGACRI
                     WFTYRSREE"
     gene            1245..2333
                     /locus_tag="PK679_09005"
     CDS             1245..2333
                     /locus_tag="PK679_09005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015285637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HPC56128.1"
                     /translation="MAEEAGLNTTQPVIPDILGLHGNFLALVVIIIGVLVAIVLFFLV
                     GWLQKRAEKTDSKIDDIVIAALGTPAVIATFLVTLYLALQVADIPPALAWIVDSKYFN
                     AIYIIPGAWALSSFAYNFISTYGHRLASATATDLDDRMVALGLIVAKYVIWFVAFLLI
                     LHTLEVDITPLLAGAGIITLALALAAQDIFSNFFGGALIAIDKPFRLNDRIQIDQYYG
                     DVIHVGPRSTRIRTLDNQIVTIPNSKLVNNYVVNYAMPEPRIKVRLPVSVAYGSDVKK
                     VREVLLNIARDAANEYSFILTEPRPIVYFLEFGASSLNFQLVVWINDFSLTFETKDAL
                     NMMIADRFAQEGIEIPFPQMDVHIKDKP"
     gene            2929..3753
                     /locus_tag="PK679_09010"
     CDS             2929..3753
                     /locus_tag="PK679_09010"
                     /inference="COORDINATES: protein motif:HMM:NF013117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HPC56129.1"
                     /translation="MTSLLFTVSYLFFSVLLGQFIVKKIQDKKTRYTAKKVLSILSII
                     VILVFTLRIWVTDTSSLIVSYGIIGAALAFALQDVFRNFVGGILIITSGYYRVGDRIA
                     MDDRVGDIMDIGILHTTMMEIRGWVNGDQPTGRLVVIPNGHVIGRAFYNYTKDHSFLW
                     DEISIPLTYESDWRRARDIILAILREETGAMTEQAEGEIARIGEKYFLPRKVVEPSVY
                     ISLTDNWIMLHARYVTDTYTRRLLNSRLNELILSAIEKEEKITIASETIAVTSIVK"
     gene            3891..4607
                     /locus_tag="PK679_09015"
     CDS             3891..4607
                     /locus_tag="PK679_09015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HPC56130.1"
                     /translation="MYGISTFCLHQHPLAHALEELSSRTNLVEIMDDGPHHIESTDLL
                     ESFPFRYTFHAPSRGVNIASLLEPIRRASVEVIGNCFDVAGEVGASVVIHPGYFAWEQ
                     EREPALRQMERSIHELAQRASEGGVTFYIENMGNWNYFFLRDPSELGIIDGVGLALDV
                     GHAHLNHCLPGFLEASISHVHIHDNDGSEDSHLPVGRGTIDFLPVLRAIRRDNAVPVI
                     EVATLEGTDESIRALDRLQE"
     gene            4729..4801
                     /locus_tag="PK679_09020"
     tRNA            4729..4801
                     /locus_tag="PK679_09020"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4762..4764,aa:Thr,seq:ggt)
BASE COUNT         1051 a         1341 c         1278 g         1132 t
ORIGIN      
        1 acccgggtcg gaagctccgg aggctcccag gatatccact accctaccgg ggctggactg
       61 taataattgg cgccttcttg ggtaaatagg ttttcaggga gaaagggaga aaaccgcttc
      121 ccgccttgcg accggcttcg ctggtcccgg agcaggaaga gcggggtctt tattcctccc
      181 gcgagcggta cgtgaaccat atccggcagg ccccttcgtg gctgaccatg cagggcccga
      241 cgggtgtccg cggggtgcat gcggtaccga aaaggcggca gtccgttggc gagaccagcc
      301 cccgcaggac cctgtcgcag aggcacgcgg tatgcttcgt cacggggcgg aagcctatgt
      361 cgaacttttt ctgggcatcg tactcctcga attttttcct gagtttcaag cctgaccggg
      421 gaatgacagg aaaacctctc cattccacgt ccgtgggttc gaagacctcg tacatcagct
      481 gttgggccct gacgtttccc tccctcgtca ccgcccgcgg ataggcattc tccacgcggg
      541 cttccccctt cctgacctgt tcgaccagca tgaggagacc aaggaggatg tcttccggtt
      601 caaaccctgc aacgacctgc gggacaggga actgctcgta ttccttatac ccggcaaccg
      661 tgcatacgtg ccccgggagg aggaatccct ggagattggc ctcgccctgt tcgaggagcc
      721 atttcatggc agggggaacg aggcggtgac aggagagaat gctgaagttc tctggcggtt
      781 cggaaaggat cgttgccgcg acggtgggtg ccgtggtctc gaacccgacg gagatgaaga
      841 caacttcctt gtcggtttgt tttgcaatct cgacagccct gtgcacgccc tggaccacgt
      901 gcacatcgcc acccgaggat tcgagggacc ccctgctccc cggaacgcgg aggaggtctc
      961 cgtacgtggc tatcgcaaag cccctcccgg caagctcgag ggcggcatcg atctccccct
     1021 gcggagtgat gcagaccggg caccctggtc ccatgacaat cttcatctgt tgcgggagca
     1081 ccctgcggag gccggcacgc gatatggctg cctcgtgcgt gccgcagata tgcatgaacg
     1141 agaggtcacg gtcgaccagt tccttcagtt tcccggctat ttctcttccc acagaaacca
     1201 tttaagatga attatttagt atacggactg ataatcatac tgttatggca gaagaggcgg
     1261 gcctcaatac gacccaaccg gtaatccccg atattcttgg actccacggg aatttccttg
     1321 cactcgtcgt catcatcatc ggtgttctcg ttgccatcgt ccttttcttc ctcgtgggct
     1381 ggctccagaa gagagcagag aaaacagatt caaaaattga cgatattgtg attgcagccc
     1441 tcgggacacc ggctgtcatt gcaacgttcc tcgttaccct gtacctggcc ctccaggtcg
     1501 cggatattcc cccggcactt gcatggatcg tggacagcaa gtacttcaac gcgatataca
     1561 tcattcctgg ggcctgggct ctctcgagct ttgcctacaa tttcatcagc acgtacgggc
     1621 acaggcttgc atcggccact gcaactgacc ttgatgaccg gatggttgcc ctcggtctca
     1681 tcgtggcgaa atacgtcatc tggtttgttg cattcctgct catcctccac acactggagg
     1741 tggatattac accactcctt gcaggggcag gaatcatcac gctggcactc gccctggcag
     1801 cccaggatat cttttcgaac ttttttggcg gcgccctgat tgcaatcgac aagccgttcc
     1861 ggttgaatga ccgcatccag attgaccagt attacgggga tgtgatccac gtcggtcccc
     1921 ggagcacgcg gatcaggacg cttgacaacc agatcgtcac gataccgaac tcaaagctcg
     1981 tgaacaacta cgtcgtgaat tacgccatgc ccgaaccaag gataaaggtc aggctccccg
     2041 tcagtgtggc ctatgggtcc gacgtgaaaa aggtcaggga ggtcctcctc aatattgcga
     2101 gggacgcggc gaacgagtat tccttcatcc tcaccgaacc ccggcccatc gtgtatttcc
     2161 tcgaattcgg tgcgtcgagt ctcaatttcc agctcgtcgt ctggatcaat gacttttccc
     2221 tcaccttcga gacgaaggac gctttgaaca tgatgatcgc ggaccgtttt gcacaggaag
     2281 gaatcgagat accgttcccg cagatggacg tgcacataaa ggacaaacca taattttttt
     2341 gggaatagca ggaaaatcga atctttttcc tccctttaag ccggtggagt tgaggttcag
     2401 gaggaagaga ggacggtctt ttccaaggtc cgctccgggg aattgataga gaaaaccaca
     2461 gagggggact gccttgttcc tgcacgcagg aaagacaggt catctcccaa gggcgctctg
     2521 gtgtctgttt ctagtgtcct tttctgatac atgattccgg catttcttat tattacatac
     2581 ctatcctgaa aatgagagaa aatgtaaaaa tttcacgcaa ttcacccttt tggcaatacg
     2641 gtgaggtggc tttacgtgat cataaatcag gtagttgtcc actcaactcc cgtaccctgc
     2701 atgcaccgca ggcagccccc tgtccaccag gaaagaaaca cgtgtggagt ggtgaatcca
     2761 tggattatca cgacgctttt atatatacac acacgttcca tgcattagtg ttgctccatg
     2821 agacagacaa gacagcagtt tctcatcgcc tcgggactga tttttttatc cgtggcaatt
     2881 ggtctggcca tgcacttttc gggcaatcca tttgtagcaa atctcttcat gacttcttta
     2941 ctgttcaccg tttcgtacct ctttttctct gtactgctcg gccagttcat cgttaagaag
     3001 attcaggaca aaaaaacccg ctatacagcc aaaaaggtcc tctctatcct gtcaatcatc
     3061 gtgatcctgg tgttcaccct gcgtatctgg gtaacagata catcatcgct tatcgtctcg
     3121 tacggaatca ttggtgcagc acttgctttt gctttacagg atgttttcag gaattttgtc
     3181 gggggcatcc tcatcattac ctcggggtat taccgggtcg gggaccggat agccatggat
     3241 gacagggtgg gggacatcat ggacataggc attttacata caaccatgat ggagatccgg
     3301 gggtgggtca acggcgatca accaaccggg cggctcgtcg tgattccgaa tggtcacgtt
     3361 attgggaggg cattttacaa ttataccaag gatcactctt ttctgtggga cgagatctcc
     3421 attcccctca cctacgagag cgactggaga cgtgcccgtg acatcatcct cgcgattctc
     3481 agggaagaga ccggtgccat gacagaacag gcagaaggtg agattgccag gatcggcgag
     3541 aaatattttc tcccgaggaa agtcgtggaa ccatcggtat acatttcatt gaccgacaac
     3601 tggatcatgc tccatgcacg ctatgtcact gacacgtata cccgaaggct cctgaactcg
     3661 cggttgaacg agctcatcct ctctgcaata gagaaggaag aaaagataac catcgcgtca
     3721 gaaacgatag cggtgacctc cattgtaaaa tagtcgcaaa tgtacgggag aggttgaggt
     3781 tccccttctt ccggtttttg tacattcgca attctcatgc cgcgtttgcg gtgcagtccg
     3841 ggacggtcac catcataaga tatttcgttt ctcttgcatg actggaaggt atgtatggaa
     3901 tctccacgtt ctgcctccac cagcaccccc tcgcccacgc cctcgaggag ctctcatcca
     3961 ggacaaatct cgtggagata atggatgacg gcccccacca catcgagtcc accgatctcc
     4021 tcgaatcctt ccctttccgt tatacgttcc acgcaccgtc ccgcggggtg aatatcgcaa
     4081 gcctcctcga accgatccgg agagcaagcg tcgaggtgat cgggaactgt ttcgacgtcg
     4141 ccggtgaggt gggagcgtcg gttgtcatcc atcccgggta tttcgcatgg gaacaggaga
     4201 gagagccggc cctccgccag atggaacggt cgatccacga actggcgcaa cgggcatcag
     4261 aagggggcgt cacgttctat atcgagaaca tgggtaactg gaactatttc ttcctgcgtg
     4321 acccctcgga actcgggatc atcgatggtg tcggtcttgc cctcgacgtg ggacatgccc
     4381 atctcaacca ctgcctcccc gggttcctcg aggcgagcat ctcgcacgtt cacatccacg
     4441 acaacgacgg gagcgaggac tcgcacctcc cggtcggccg gggcactatc gatttccttc
     4501 ccgtgctacg tgccatcagg agggacaatg cagtgcccgt gatcgaggta gcgacgctcg
     4561 aaggaacgga cgagagtatc cgggcactcg accggttgca ggaatgacat gcgatgggga
     4621 ggaggctggt gccctttttc cgacctccag aaccttttca cggggctccg gggagtcttt
     4681 ttccgcaatc ttttaaacgg ttcacgtcga ctattgttct cacatcgtgc ctttgtggct
     4741 cagtcggtag agcgacacct tggtaaggtg taggtcgggg gttcgattcc ccccaaaggc
     4801 tc
//
LOCUS       DAOOJU010000060         4572 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_14848_length_4572_cov_14.853221, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000060 DAOOJU010000000
VERSION     DAOOJU010000060.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 4572)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4572)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4572
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14848_length_4572_cov_14.853221"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            3..74
                     /locus_tag="PK679_09025"
     tRNA            3..74
                     /locus_tag="PK679_09025"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Arg,seq:ccg)
     gene            249..791
                     /locus_tag="PK679_09030"
     CDS             249..791
                     /locus_tag="PK679_09030"
                     /inference="COORDINATES: protein motif:HMM:NF013539.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HPC56131.1"
                     /translation="MQEIPRIPGLYRTFLEKTLDSIERMDSETGTLSRLIDEARAVHI
                     FGFGRSGTAALAMAIRLRHFLAPERQVFWLGDGVRDPIRKDDLVILFSGSGTREEVLH
                     FLRKAEGAGAHCVAVTGSPGSALARGARLTIVLPSIGSEVCYGGGDFELAAWTFQEVF
                     LTMYGRSRAVPDGKITFNHV"
     gene            complement(804..977)
                     /locus_tag="PK679_09035"
     CDS             complement(804..977)
                     /locus_tag="PK679_09035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56132.1"
                     /translation="MVETTEKCDVCGRVAIGIQVMGCCASKVCEDHADPHLKALKPGE
                     KLEWGACFFSRYG"
     gene            complement(1452..1973)
                     /locus_tag="PK679_09040"
     CDS             complement(1452..1973)
                     /locus_tag="PK679_09040"
                     /inference="COORDINATES: protein motif:HMM:NF019314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HPC56133.1"
                     /translation="MDDTGRIRLARKAGVILSLGAGSFIAGYFSLQLTIGSAPVFDPR
                     DILVVCGGVLAGPVGGGLVGLSAGIAGQEPPVFVPLYALGGILSGVLARFLRREKRWM
                     PGAALGLGACYPLAGLLMMGMGLWDRIAALAFQALVMQFTCILVLSIIGSLDPAIFSW
                     EDEMEKSPKDSFT"
     gene            2106..2702
                     /locus_tag="PK679_09045"
     CDS             2106..2702
                     /locus_tag="PK679_09045"
                     /inference="COORDINATES: protein motif:HMM:NF024698.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HPC56134.1"
                     /translation="MQVPDRLVTERLHLRHFTAADAPFVVDLVSDPAIAAGVLELPFP
                     YTLADALEWICQLEEGRERGTEYAFAVSERERGTLAGAASLRINCEHSHAELGYWIGR
                     DFRGKGYAREAASALLEFGFFGLGLHRIYARHLAWNTASARVLTGIGLTHEGTMRGHA
                     LKWGSFHDIEVYGICIDEYYRKHAAGKEKRGVGPKGGS"
     gene            2703..3512
                     /locus_tag="PK679_09050"
     CDS             2703..3512
                     /locus_tag="PK679_09050"
                     /inference="COORDINATES: protein motif:HMM:NF016873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-formylglutamate amidohydrolase"
                     /protein_id="HPC56135.1"
                     /translation="MRERLPVLISVPHGGTLVPVRIRDRVCLDDRALSYYSDPATQDL
                     YDMRGIAAAFLQSDVSRVIIDLNRPPYHLPPKYPDGVVKTKTSLGHPVWKEDRMPDLA
                     CIHKLLLGDYFPYHAKADRFLLSGKVSVALDCHAMVPFGLPGQPDAGKKRPLFCLSNN
                     GDDEGHARPGTLPTCPADWIQSLRDAIRDHFAGEGSIWINHPFHGGFIMNAHYWHAGI
                     PWIQIEMNRSLYEEDGSSPETGSLTDAGKVKELNRVFRGIIHEWTRVIGVR"
     gene            complement(4045..>4572)
                     /locus_tag="PK679_09055"
     CDS             complement(4045..>4572)
                     /locus_tag="PK679_09055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5698 domain-containing protein"
                     /protein_id="HPC56136.1"
                     /translation="ILVARIVETSLETIRTIYINRGHTNLAAGIGVVKVAIWLLSTGL
                     VFSNLQNILGLVAYVAGYAIGTVIGMQMEDRISIGNVVVRVFYPGDPAPLIRRFGEMG
                     YGITRLDGTGYLSSPVAVLFMVVPRANLKELLSVLDTDYPRLIYTIEDIRKGSDESRI
                     FHGEKKPWWKRFLGI"
BASE COUNT         1003 a         1330 c         1276 g          963 t
ORIGIN      
        1 cagccccggt agggtagtgg atatcctggg agcctccgga gcttccgacc cgggttcaaa
       61 tcccggctgg ggcgtcaccc attcaccttt ttaacaagat cctttttcct ccccggaact
      121 tcagagccgg gttttctgca tcgtctccgc gtgacctgca ggatgcgggc cggtccccgc
      181 aggagacgct ttcttaaacc ctgaacgcca accacacaag ggaatacagg cggatcgttg
      241 gcgtaaccat gcaggaaatt ccccgcattc ccggattgta caggacgttc cttgaaaaaa
      301 ccctcgattc aatagaacgg atggatagcg aaaccggcac cctgtcgagg ctcatcgatg
      361 aggctcgcgc cgtgcacatt tttggtttcg ggaggagcgg gactgcggca cttgccatgg
      421 caatccggct gcgccatttc ctcgcaccgg aacgacaggt cttctggctt ggtgacgggg
      481 tcagggatcc catccggaaa gatgacctcg tgattctctt ctcgggctcg ggaacaaggg
      541 aagaggtcct ccacttcctc cggaaagcag aaggagcagg ggctcattgt gttgctgtga
      601 cgggctctcc cggatcggct cttgcacggg gcgcccggct cacaatcgtg ctcccgtcca
      661 tcgggagcga ggtgtgttac ggcgggggtg atttcgagct tgccgcatgg actttccagg
      721 aggtcttcct gaccatgtac ggccgatcac gtgctgtccc ggacgggaag ataaccttca
      781 accatgtctg atcatgcagg ttttcatcca taccgggaaa agaaacacgc cccccattca
      841 agcttctctc cgggtttcaa ggccttaagg tgcgggtctg cgtgatcctc gcagaccttc
      901 gacgcacagc agcccatcac ctgtatcccg attgccaccc tgccgcatac atcgcatttt
      961 tccgtggttt caaccatttt tatcctctct cctgtcccct ttctcccggg cagcaatcaa
     1021 gccgcggggt gcggggagat gcctgccagg ggtgagaagt ggcacctgca taatctttat
     1081 tattctggca tgcgatatgt ggcatgctag acaggtgacc atgatttctc acgtggtcgc
     1141 ttatttattg tctggcaccc tccatgtgga cggttttgca gccctccacg ccttgaatgg
     1201 cctggtcatc cggtatcaac tccccaaacg accgcaccgg gtacctcgcg gtcgatacca
     1261 ggatgacctc tggcttttcc catcgcttct ccggctgaac gtgtttttcc gtatcccgat
     1321 gtttccagcc catttacccc ggaaaaaggc aaggcatgaa cacacgctct tttgaaaaag
     1381 atcttttccg tggatattgt ggccggccgg accctttctc actcatggaa atgcatttcc
     1441 ggcgccccat ttcacgtgaa agaatctttg ggagattttt ccatttcatc ctcccatgaa
     1501 aaaatggcgg ggtcgaggga cccgatgatg gagaggacaa ggatacacgt aaactgcatg
     1561 acgagtgcct ggaacgcaag tgcagcaatc ctgtcccaca atcccattcc catcatcagg
     1621 agaccggcaa ggggatagca ggcacccagt cccagggccg cacccggcat ccacctcttt
     1681 tcccgccgga gaaaccttgc caagactccg ctcaaaattc ctcccagggc atagaggggg
     1741 acgaacacag gaggttcctg gcccgctatc cccgcagaaa gcccgacgag tccaccgccg
     1801 acgggaccgg ccaggacccc cccgcagaca acgaggatgt cccttggatc gaagaccggt
     1861 gccgacccta tggtgagctg gagggaaaaa taccctgcaa tgaacgaacc cgccccgagg
     1921 gagaggatta cgcctgcttt ccgtgccagt cggatccggc ctgtgtcatc catttctctt
     1981 attcgttcgg actgtcctcc ctaaaaggtt gccggaaaat ccgtcggtgg caaggaaaat
     2041 gcagaccggt tttcaataac ccatatggtg caggaaggca accatgatag gagaggagtg
     2101 ttcccatgca ggtccccgac aggctcgtga cagaaaggct tcacctgcgg cattttaccg
     2161 cagccgatgc ccccttcgtc gtggatctcg tctccgaccc ggcgattgct gcgggagtcc
     2221 ttgaactgcc gttcccctat acccttgccg atgcgctgga atggatctgc cagctggaag
     2281 aggggaggga gcgcggcacg gaatatgcgt ttgccgtcag cgaacgggaa cgggggactc
     2341 tcgcgggtgc tgcatccctc cggatcaact gcgagcattc ccatgcagaa ctcgggtact
     2401 ggattggcag ggatttcagg gggaaggggt atgccaggga agccgcatcc gcactccttg
     2461 aattcgggtt cttcgggctt ggactccaca ggatttatgc ccgtcatctg gcgtggaaca
     2521 ctgcctcggc ccgggtcctc accggtatcg gcctcacaca cgagggaacg atgcggggcc
     2581 atgccctgaa atggggatcg ttccacgata tcgaggttta tgggatatgc atcgatgaat
     2641 actacagaaa gcatgctgca ggaaaggaga agcgtggtgt cggaccgaaa ggggggtcat
     2701 gaatgcggga gaggcttccc gtcctgatat cggtccccca tgggggaacc ctcgtccccg
     2761 tcaggatcag ggacagggtg tgcctcgatg accgggcact ctcctattac agcgacccgg
     2821 caacgcagga tctgtatgac atgcggggga tcgctgctgc cttcctgcaa tcggacgtat
     2881 ccagggtaat aatagacctc aacaggccgc cctaccacct tccgccgaaa taccccgacg
     2941 gcgtcgtcaa gacaaagacg tcgcttggtc acccggtctg gaaggaggat cgcatgccgg
     3001 acctcgcatg tatccacaag ctcctccttg gggactattt tccctaccat gccaaagcag
     3061 acaggtttct cctttccgga aaggtctcgg ttgctctcga ctgccacgcg atggtgcctt
     3121 tcgggcttcc gggacagcct gatgcgggaa aaaagcgtcc ccttttctgc ctctccaaca
     3181 acggtgacga tgaggggcat gcacgaccgg ggactctccc gacctgcccg gcagattgga
     3241 tccagagcct ccgcgacgcg atccgggatc actttgccgg agaggggagc atctggatca
     3301 accacccgtt ccacggtgga ttcatcatga atgcgcatta ctggcacgcg ggaatcccgt
     3361 ggatccagat cgagatgaac aggtctctct atgaggagga tggatcgagc ccggagacag
     3421 ggtctttgac cgacgccggc aaagtgaagg aactgaaccg ggtctttcgc gggatcatcc
     3481 atgaatggac ccgtgtcatc ggggtaaggt aaaatccggg atcgatgata ccacaggctt
     3541 ccttttgcct ctcccttccc ggcaacctac ccgctttggt cgggttgatt gaactacccg
     3601 gatcgatggt caaagcccgg agtggaatca gggagagatg aaaccctctc aatatatgaa
     3661 aaaagcggat ttctattatt ctctgcaggg gagagggact tcccaatcct tctcccggga
     3721 gagaggagat gcggattact catccaagga ggctttcggt actgcgggca agggttgccc
     3781 tgccggccag cggaacacgg atacctgccc ggcgggggag aacgccaaaa agaccacggt
     3841 actgaacgtg aactgatttg aaaatgatac cggatcgtga tcgggacaca ggtacacaga
     3901 atgaacatgg ctgagccatt ccacggttca cacccatgac tgacccgtgc ggccggccac
     3961 gaaaaagaga aaatcacgac gattttttcc tgggaaaaaa gccatcggga tctctaagat
     4021 cctctcatca ccccctttca cccatcagat gccaaggaaa cgtttccacc agggcttctt
     4081 ctctccgtga aagatccggc tctcgtcact ccccttcctg atgtcttcga tggtgtagat
     4141 gaggcggggg taatccgtgt cgaggaccga gaggagttct tttaagtttg cccgcgggac
     4201 aaccatgaag agcaccgcaa ccggtgacga gaggtaccct gttccgtcca ggcgcgtgat
     4261 gccatagccc atctctccaa acctcctgat aagcggagcc gggtcacccg ggtaaaaaac
     4321 cctgacaaca acgttcccga tactgatacg gtcctccatt tgcatcccga taacggtgcc
     4381 gattgcatac ccggcaacgt atgccacgag accgaggata ttctggaggt ttgaaaaaac
     4441 aagtcccgtg gacagcagcc agattgcaac cttgacaacg ccgatgccgg cggcaaggtt
     4501 cgtatggccc cggttgatgt aaatcgtccg gatcgtttcg aggctcgtct cgacgatccg
     4561 ggcgacaagg at
//
LOCUS       DAOOJU010000061         4519 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_15052_length_4519_cov_7.771729, whole genome shotgun sequence.
ACCESSION   DAOOJU010000061 DAOOJU010000000
VERSION     DAOOJU010000061.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 4519)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4519)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4519
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_15052_length_4519_cov_7.771729"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(187..3201)
                     /locus_tag="PK679_09060"
     CDS             complement(187..3201)
                     /locus_tag="PK679_09060"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56137.1"
                     /translation="MTNLYRILYVDDEPALLDIVRLYLEKKKRFIVDTATSAGEALKK
                     MQCNPPYDAVVCDYQMPVMDGIGFLRVLRRHGDDTPFIIFTGKGREDIVIQALNEGAD
                     FYLQKGGDPASQFAELAHVIQKVVRQKRIESSIRDMERREADILNFLPDATFAIDLHG
                     TVIAWNRAMEKMTGIPADEILGRGDYEYALPFYHERRPILIDLVLKADPGTEAKYPYI
                     RREGETLISEIFIPHLNGGKGAYLWFLASPLYNSRGEVAGAIESIRDVSEWKDVEKEM
                     EERGRFLSTLIANLPGFAYRCRNDRNWTMEYISDGCRDVTGYEPSDFIGNATLAFNDI
                     IHPDYRDVLWNLRQKNLAEQRVFEYEYPITTRSGQTRWVWERGRGIFSEEGTLLYLEG
                     FITDITVRKKTEDELRRSEEQLALAIEGSGAGLWDWKVQTGELSCNERWAGIVGYTLD
                     ELAPLSIGTWNRLVHPDDLEVSNSLLRKHFAHEIPFYECEVRMRHKDGHWVWILDRGK
                     VTEWDGEGRPVRMTGTHLDITERKRIEEELRESREILHSFIGNLPVGLYRNTPGPRGE
                     YILANPYVARLHGFGTLDELFTHPASDLYEDPSERLAFSDELVRAGSVFGRELHLKRK
                     NGERFWGRVSAVAVRDEKGNIKYFDGVIEDITEQKKAEKAFRESEKKYRDLLEKLPEQ
                     VIVHRGGHILYANPATFRTLGYNPEEVINRHVLEFIPPEYHPQVVETIRKRATGQPPE
                     HYDIEVIGKDGSRRTVRVSGRPITFEGEPATLIVLFDITERKRAEEALRQANHKIALL
                     NTITRHDINNHLLVLSGLLDLLQDEDHPADREAYLEKARIAVARILATIRFTRDYEQI
                     GGSEPQWQDCHALVGAVRNDFVSPNFAVVNDIPRGLDIFSDHMISRVFANLVDNAIRH
                     GEGVRSVRFFAGREEDRLVIFCEDDGAGIPEGEKEKIFERGYGKNSGFGLFLAREILG
                     MTGMTIREDGVPGKGARFVITVPKGSWRQEGE"
     gene            complement(3373..4341)
                     /locus_tag="PK679_09065"
     CDS             complement(3373..4341)
                     /locus_tag="PK679_09065"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HPC56138.1"
                     /translation="MVPGIAAGINSGKGHSFLIHLPSPSSELSVIDILYVDDDLDFLE
                     ITKRMVEKSGEIAIETATSAENALAMMEDRTYDVIVSDYQMPRTDGIEFLKMLRGSGN
                     TTPFIIFTGRGREEVVIQAYDCGADFYVQKGGDLKAQFRELEHKIVQAVRIHEAESAF
                     RESEERYRSVVENATEGIVVVQDERILYANPRALEMVEATPDEVTGKNFALFVHPGDI
                     PLVTERYRRRQGGEKVPKTYDFRVVGKAGLVTWVQASAVLIPWNRRTATLALLADITE
                     RRERENGVRQQNVALEKTVEDQAARLEKSENEKKDLLRRLAGDDAG"
BASE COUNT          868 a         1344 c         1246 g         1061 t
ORIGIN      
        1 atgcatgggt cctccggggg tgcggggcat ttctcgtcct gttcgggata tcctatctcg
       61 ccttcgccct tgaacctgcc ttccggtcct aaaaaagtgg tgtgtccacc ggaaaaaact
      121 gcatctcttt gtcttgactg atcccggttg gccctcatgg gatgagaagg catcagggga
      181 gtatctttat tctccctcct gccgccagga acccttgggc acggtgatga cgaagcgggc
      241 ccccttcccc ggcacgccgt cctccctgat ggtcatcccg gtcattccca gtatctcgcg
      301 tgccaggaag aggccaaagc cgctattttt cccgtatccc ctttcaaaga tcttctcctt
      361 ctccccttcg ggaatgccgg ccccgtcatc ctcgcagaaa atgacgagcc tgtcttcttc
      421 ccgtcctgca aagaaccgga ccgacctcac tccttcccca tggcggatgg cattgtcaac
      481 gaggtttgca aagacccggg atatcatatg gtcggaaaag atgtccagtc cccgcggtat
      541 atcattaaca accgcgaagt tcggtgaaac gaaatcgttc ctgacggccc cgacaagcgc
      601 atggcagtcc tgccactggg gttcgctgcc cccgatctgc tcgtaatccc tcgtaaacct
      661 gatggtcgcg aggattcggg ctacagcaat ccgggccttt tcgaggtatg cttccctgtc
      721 ggcggggtga tcctcgtcct gcaggaggtc caggagaccc gacaggacga ggagatggtt
      781 attgatgtcg tgccgggtga tggtattgag gagggcgatc ttgtggtttg cctgccggag
      841 tgcttcttct gcacgtttcc gctcggtgat gtcaaagaga acgatgagag ttgcaggttc
      901 tccctcgaac gtgatcggtc tcccgctgac cctcactgtc ctccgtgacc cgtccttgcc
      961 gatgacctcg atatcgtagt gttccggcgg ctgcccggtc gctctcttcc gaatagtctc
     1021 aacgacctgg ggatggtatt ccggggggat gaactcgagg acatggcggt tgatcacctc
     1081 ttcagggtta tatccaagtg tcctgaaggt tgcggggttt gcgtacaaaa tatgtcctcc
     1141 ccggtgcacg atgacctgtt cggggagttt ttcgaggaga tcccggtatt tcttttcgct
     1201 ctcccggaac gctttctctg ccttcttttg ctcggtgatg tcctcgataa ccccgtcaaa
     1261 gtacttgatg ttgccctttt catcccgtac cgcgaccgca gagacacgcc cccagaaccg
     1321 ctccccattc tttctcttaa gatgaagctc cctgccaaaa acggaaccgg cccgcaccag
     1381 ctcgtcggag aacgcgaggc gttcggaggg atcttcgtac aggtctgatg caggatgggt
     1441 gaataattca tcgagagtcc cgaacccgtg caggcgggca acataggggt ttgccaggat
     1501 gtactcgccc cggggaccgg gagtgttccg gtaaagaccg accgggaggt tcccgatgaa
     1561 actgtgaaga atttccctgc tctcacggag ctcctcctcg atacgtttcc gctcggtaat
     1621 atcgaggtga gtccctgtca tgcgcaccgg tcttccctcc ccgtcccact ctgtcacctt
     1681 tccccggtca agaatccaga cccagtgccc gtccttgtgc cgcatccgca cttcgcactc
     1741 gtagaaggga atctcgtggg cgaaatgctt ccggagcagg gaattggaaa cctcaaggtc
     1801 atcgggatgc acaaggcggt tccatgtccc gatgctcaga ggtgcaagtt catccagcgt
     1861 gtaccctacg atcccggccc acctctcgtt gcaggagagt tccccggtct gaaccttcca
     1921 gtcccagaga ccggccccgg acccctcgat cgcgagggcg agctgctcct cgctcctgcg
     1981 aagctcgtcc tcggtcttct tccggaccgt gatatcggtg atgaatcctt ccagatagag
     2041 cagggtgcct tcctccgaaa agatccccct cccccgttcc cagacccagc gggtctggcc
     2101 actccgggtg gtgatggggt actcgtactc gaagacccgc tgctccgcga ggtttttttg
     2161 cctgaggttc cacaggacat cccggtaatc ggggtggatg atatcattga aggcaagcgt
     2221 cgcattaccg atgaaatcgg acggctcgta ccctgtcacg tcgcgacacc cgtcgctgat
     2281 atattccatc gtccagttcc ggtcgttcct gcaccggtag gcaaagcccg gaaggtttgc
     2341 gatcagcgtg gagaggaacc tccccctctc ttccatctcc ttttccacgt ccttccactc
     2401 gctcacgtcc cggatggact cgatggcgcc ggcaacctct ccccgcgaat tgtagagggg
     2461 ggaagcgagg aaccagaggt aggccccttt tcccccgttg agatggggga tgaagatctc
     2521 cgagatgagg gtctccccct ccctcctgat gtacgggtat tttgcctcgg ttccgggatc
     2581 ggccttgagt acgagatcga tgagaatggg gcgccgttcg tggtaaaacg ggagggcata
     2641 ctcgtaatca cccctgccaa gtatttcgtc ggcaggaatc cccgtcatct tctccattgc
     2701 acggttccat gcgatcacgg taccatgaag gtcgatggca aaggtggcat ccggcaaaaa
     2761 gttgaggatg tctgcctcgc ggcgttccat gtcgcggatg cttgactcga ttcttttctg
     2821 gcggacaacc ttctgtatga cgtgggcaag ctcggcaaac tgggatgcgg gatcacctcc
     2881 cttctggagg taaaagtcgg caccctcgtt cagggcctgg atgacaatat cttccctgcc
     2941 tttcccggtg aatatgatga aaggagtatc atccccgtgc ctgcggagaa ctctgaggaa
     3001 cccgatccca tccatgacag gcatctggta atcacagacg acagcatcgt acggcgggtt
     3061 gcactgcatc tttttcagtg cttcgcctgc agacgttgcc gtgtccacga taaacctctt
     3121 cttcttctcg aggtacagcc ggactatatc gagcagtgcc ggttcatcgt caacgtacag
     3181 gatgcgatac aggtttgtca ttgctcctga tcccggtttt cattcacgaa gggaaatgga
     3241 tgaagaagga tggaatctac aggagaaaaa ctcatctctc gtgaaacacc ggcgggtgca
     3301 atgcctggaa cggagggatg aactggcagg aataaaggtc acccgtaatg gtggaggaat
     3361 tgatcgttcc tgtcagccgg catcatcccc ggcaagtctc ctgaggaggt ctttcttctc
     3421 attttctgac ttttccagcc gggcagcctg gtcttccaca gtcttttcga gggcaacgtt
     3481 ttgctgacgg acaccatttt cgcgctccct cctctccgtg atgtctgcca ggagagcgag
     3541 ggttgccgtc cggcggttcc aggggatcag gactgccgat gcctggaccc aggtgacgag
     3601 ccccgctttt cccaccaccc ggaaatcata ggtcttgggg accttctctc ccccctgcct
     3661 ccggcggtac cgttcggtca cgagcgggat gtccccggga tggacgaaga gggcgaagtt
     3721 ctttcctgtc acctcgtcgg gagtggcctc taccatttcc agggcccgcg ggttggcata
     3781 caggatacgt tcgtcctgca cgaccacgat cccctcggtc gcgttctcga cgacggaacg
     3841 gtatctctcc tcgctctccc ggaatgcaga ctctgcctcg tggatccgta ccgcctgcac
     3901 gatcttgtgc tccagctcgc ggaactgtgc cttcaggtct ccccccttct ggacgtaaaa
     3961 gtcagcacca cagtcatacg cctggataac gacctcttcg cggcccctgc cggtaaaaat
     4021 gatgaagggt gttgtgttcc ctgacccccg gagcatcttc aggaactcga tgccgtcagt
     4081 ccggggcatc tggtagtccg agacgatgac atcgtaggtt cggtcctcca tcatcgcgag
     4141 ggcattttct gcagaagttg cagtctcgat cgcgatctcg ccggacttct cgaccatgcg
     4201 cttcgttatc tcgaggaaat cgaggtcgtc atcgacgtag aggatatcga tcacggagag
     4261 ctccgaggaa ggggagggga ggtgaatgag gaaagagtgc cctttcccgc tattaatacc
     4321 tgccgctatt ccgggaacca tgagatgata acggcatcgg gagaaagggt tttttgggga
     4381 aaaatggtat cgtgccatcc cccggttgtt ccactggatg atgcaccccg tcaatcccgc
     4441 cgcgggaaca attcgggaaa aggggggact tttccctgct ctccgtcgca gttcaggcct
     4501 tgccaaagta cttcttgac
//
LOCUS       DAOOJU010000062         4018 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_17394_length_4018_cov_5.053495, whole genome shotgun sequence.
ACCESSION   DAOOJU010000062 DAOOJU010000000
VERSION     DAOOJU010000062.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 4018)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4018)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4018
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_17394_length_4018_cov_5.053495"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..3656)
                     /locus_tag="PK679_09070"
     CDS             complement(<1..3656)
                     /locus_tag="PK679_09070"
                     /inference="COORDINATES: protein motif:HMM:NF012311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2341 domain-containing protein"
                     /protein_id="HPC56139.1"
                     /translation="MKNEALHPIICFFLVVALLSPVLAGSDGPQDGVLPETPSVRAQY
                     QITITPSPAPDETLPPPGPLAGDTLPAIPGSDTPSEIPPGKDSPTLSQPENTGTDNPS
                     GTPAATDSPTLSQTPAPDPAPASGRVSPAHDGGEAGRSGNQPQKEQEEYAPGELIVRF
                     KPSAVSDEKSRAQVTSRAHRAVGATVKKEYSRKGMAGTQVVKLPPGKSVEEAIAEYQA
                     DPAVLSATPNYKISLLAIPDDPLYSQEWGLEKVEAPRAWDRTTGSADVIIAVADTGID
                     YTHPDLSGALWSNSGEIPANLIDDDGNGYVDDAIGWDFFGDTNDPMDGNGHGTACAGV
                     IGARGNNNLGISGVLWNAKLVPLKVIGPEGYGYESDAIDAVLYADGIGADIISFSWGG
                     TYPYPALRDAMASSPALFICAAGNSGTDNDENPVYPASFDLPNVISVSATDESDRLAP
                     FSNFGAASVAIAAPGAGILSTARGGGYSSFSGTSMAVPFVTGIAGLVKAENPGYSSLH
                     LKEAILASADRLSSLEGKVATGGRVNAPRALGVPVSPAPTTPLPTPTPTQTPVPVYEP
                     GEAPPNPAFVRFLEQGVADSGAAGEPTGYIPSPLDLSYLSPSGTEIATFAFPSSYSLV
                     SEGRVTPVRDQGSCGDCWAYGAYGSLESTLMPGEPRDFNEWHLNANHGFDYPSCAGGN
                     NDMSNAYLARWSGPMNEGQNTPVQKHVQEVLYLPKKTSATDNDHIKAAIVNYGGVSAS
                     FYWNSAYMRTGGYYYPPSGSAGSGNHMITIVGWDDTRSVTGAPGPGAFLCKNSWGSSW
                     NGNGYFWISYYDKFLGHEELAVFKSAEPVTNYDYIHQYDPLGWISSLGYGTLSAWSAN
                     VFTAPVAQSINAVGFYTTETGSSYEIYVYTDPTTGQPRSGTLRASRSGTMQYAGYHTV
                     PIDPVTVNQGQKFSVVVKTTNPAYTYPIAFETRISGYSSAATASAGQSFISPDGSSWS
                     DLTASYSNSNACIKAFGNIRRDPVADFRATPAQGVRNLSVQFTDLSSNSPTSWQWNFG
                     DGSPNATGKNPVHTYTAAGTYTVTLTVTNPYGSSTLQKTDYITVTDPPPFLPGWSSRK
                     LHTLAGSSSGDLADYQVPFVVHRTTGTDNGRDVYLGTDVQSDFRDIRFTTTDNSVLPY
                     WIESVTTDSALVWVKVPSIPSTGTQLYLYYGNGTAPSLSDGDATFLFFDDFPGTALDT
                     SKWEDRSNVAGTVAV"
BASE COUNT          779 a         1076 c         1335 g          828 t
ORIGIN      
        1 accgctacag taccggcgac attgctccgg tcttcccact tggaggtatc cagtgccgtt
       61 cccgggaaat cgtcgaagaa caggaacgtc gcatccccgt cactgagcga gggagcggtc
      121 ccgttcccgt agtagaggta gagttgcgtt ccggtggagg ggatggaggg gactttgacc
      181 cagacgaggg cagagtctgt ggtgaccgac tcgatccagt agggaaggac ggagttatcg
      241 gtggtggtga accggatatc gcggaaatcc gactgaacat cggttccgag gtacacgtct
      301 ctgccgttgt cggtaccggt ggtcctgtgg acgacgaacg ggacctggta gtcggccagg
      361 tcaccggacg atgacccggc gagggtatgg agtttgcggg aggaccagcc gggcaggaac
      421 ggtggcgggt cggtgacggt gatgtagtca gtcttctgga gggtggaaga accgtagggg
      481 ttggtcacgg tgagggtgac ggtataggtc ccggccgcag tataggtatg gaccgggttc
      541 ttcccggtgg cattgggaga gccgtccccg aagttccact gccaggatgt tggggagttg
      601 gacgagaggt cggtgaactg aacggaaaga ttcctgaccc cctgtgcggg agtcgccctg
      661 aaatccgcga ccgggtccct gcgtatattc ccgaatgcct tgatgcaggc attgctgttg
      721 ctatacgatg ccgtgagatc actccatgac gacccatcgg ggctgatgaa gctttgtccc
      781 gcacttgcgg ttgcagcgct cgaatagccg gaaatgcgtg tttcgaatgc aatggggtat
      841 gtatacgcgg ggttcgtggt tttcacaaca acggagaact tttgtccctg gttgacagtg
      901 acagggtcaa tggggactgt atggtaaccg gcatactgca tggtccccga acggctggct
      961 ctcagggtcc cgctccgggg ctgaccggtg gtggggtctg tgtagacgta tatctcgtat
     1021 gatgaacccg tctccgtggt gtagaatcca actgcattga tggactgggc aaccggtgca
     1081 gtgaagacat tcgcactcca tgcggatagt gtcccatacc caaggctgga tatccacccc
     1141 agcgggtcat actggtggat atagtcgtaa ttcgtgaccg gttcggcgct cttgaaaacg
     1201 gcaagctcct cgtgtccaag gaacttgtcg taataggata tccagaagta gccgttccca
     1261 ttccagctgc tcccccagct gttcttgcag agaaaggcgc cggggccggg cgctcctgtc
     1321 acggatcggg tatcgtccca cccgacgatg gtgatcatgt ggttgccgct ccctgcggaa
     1381 cccgacgggg gatagtaata gccacccgtt ctcatgtatg cactgttcca gtagaacgag
     1441 gcggacacac ccccgtagtt tacgattgcg gccttgatat ggtcattatc ggttgcactt
     1501 gtcttcttcg ggaggtagag gacttcctgg acgtgtttct ggacaggagt gttctgtccc
     1561 tcgttcatcg ggccgctcca gcgggcgagg taggcattgg acatatcgtt gttgccgccg
     1621 gcacaggaag gatagtcgaa cccatggttg gcgttgaggt gccactcgtt gaagtcccgt
     1681 ggttctcccg gcatgagggt cgattccagc gatccgtacg caccgtatgc ccagcagtca
     1741 ccgcacgagc cctggtccct tacgggcgtg acccgccctt ccgagacgag ggaataactg
     1801 gagggaaacg caaaagttgc aatttccgtt ccggatggcg agaggtacga gaggtcgagg
     1861 ggcgagggga tgtaaccggt gggctcaccc gctgccccgg aatccgccac gccctgctcc
     1921 aggaaccgga cgaatgccgg gttcgggggg gcttccccgg gttcatagac cgggacaggg
     1981 gtttgcgtcg gcgtgggagt agggagggga gtcgtcggtg ccgggctgac ggggacaccg
     2041 agcgcacggg gtgcattgac cctgccgccc gttgcaacct ttccctcgag ggaggaaagg
     2101 cggtctgcgg aggcaaggat ggcctcttta aggtggaggc ttgaatagcc ggggttttcc
     2161 gccttcacga gacccgcaat accggtgaca aaggggacgg ccatcgaggt cccggaaaag
     2221 gacgagtatc ccccgcccct tgcagtcgag aggatgcctg caccgggtgc cgcgatagcg
     2281 acagatgccg ccccgaagtt ggagaacggc gccagccgat cggattcatc ggttgcagac
     2341 acgctgatca cgttcgggag gtcaaacgat gcaggataga cggggttctc gtcgttgtca
     2401 gtcccgctgt tcccggcggc acagatgaag agggcgggag aagatgccat cgcgtcccgg
     2461 agtgcagggt agggatacgt cccaccccat gagaagctga tgatatctgc cccgattccg
     2521 tctgcataca ggacggcatc gatggcatca ctctcgtacc cgtacccctc cggcccgatc
     2581 actttcaggg gaaccagttt tgcgttccag aggacacccg agataccgag gttgttgttc
     2641 cccctcgccc cgatgacccc tgcacaggca gtaccgtgcc cgtttccgtc catcgggtcg
     2701 ttggtgtcac caaagaagtc ccagccgatc gcgtcgtcga catacccgtt gccatcgtcg
     2761 tcgatcaggt tagccgggat ctccccgctg ttggaccaca gggccccgga gaggtcgggg
     2821 tgcgtgtaat cgattccggt gtcagcgacc gcgatgatga cgtcagccga cccggtcgtc
     2881 ctgtcccacg cacggggagc ctcgaccttc tccagccccc attcctggga atagaggggg
     2941 tcgtccggga ttgcaaggag cgagatcttg tagttgggtg tggcagagag cacggcgggg
     3001 tccgcctggt actcggcaat ggcctcctca acgctctttc ccggcgggag cttgacgacc
     3061 tgggtcccgg ccatgccctt ccggctgtat tcttttttca ccgttgcgcc gaccgcccgg
     3121 tgtgcacggg acgttacctg agcccgggat ttctcgtcgg agacagcaga aggcttaaac
     3181 cggacgatga gttcgccggg agcgtattct tcctgctcct tttggggctg gttaccactt
     3241 cgccctgctt ctcccccgtc atgggcgggt gatacccgtc ctgatgcggg ggctggatcc
     3301 ggtgccgggg tctgggaaag ggttggagaa tctgttgcgg cgggggtccc ggacggattg
     3361 tcagtgcccg tattctccgg ttgggaaagg gttggactgt ctttcccggg aggaatttcc
     3421 gatggggtgt cgctgcccgg tatcgcgggc agggtgtcac cggcaagggg acccggggga
     3481 ggaagggtct catccggtgc aggacttggg gtgatagtga tctggtactg tgcgcggaca
     3541 gagggagtct ccggtaacac tccatcctgc gggccatccg aacctgcaag aacgggtgac
     3601 aggagtgcca cgacaaggaa gaaacagatg atgggatgca gggcctcatt cttcatagaa
     3661 attacccctg gatggggaaa cctggccggt gatgctcagg attgcctggt atacgtgatt
     3721 aatactagga ggtacggggg aaaaagagat cggtgacgaa aggagagggt ggacagaagg
     3781 gggaaaacac cgtccgggaa acggtctgtg gagaaaagag ggtcatcctg acgttttttt
     3841 cgaatttttc gatgaacttt ggaccgagcc ggacgaaaaa tgcgggaaag cgtggaccgg
     3901 cgaaggggaa tcacatgaaa gccccatgat tcccgacccc cgagcattac catggccccg
     3961 gaacgcttgc ttgaagtcgt ccgaatacac ttctctcccg ccagaagggg gacgtttc
//
LOCUS       DAOOJU010000063         3572 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_20261_length_3572_cov_15.915269, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000063 DAOOJU010000000
VERSION     DAOOJU010000063.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3572)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3572)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3572
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20261_length_3572_cov_15.915269"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            200..910
                     /locus_tag="PK679_09075"
     CDS             200..910
                     /locus_tag="PK679_09075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HPC56140.1"
                     /translation="MKSDLRNRLAEKMAGEITLSDSPGKALKKWRMSFNIPQAVLSEH
                     LDVSPSVISDYESGRRKSPGTAVVGKIVDTILSIDEANGGKYIKKFGKILYSDVDDDV
                     IYDIHDYPSPVPLTRFAGLIACQPVCGSLSQAIYGYTVINSLNAITQLSSNEFNRIYG
                     WSTERALIFTDVTSGKSPMVAIRVTPFKPRAVVLQGIEPALVHPLVPKMAEKDRITVL
                     CTGMDVEQIVHVLREEQW"
     gene            904..1956
                     /locus_tag="PK679_09080"
     CDS             904..1956
                     /locus_tag="PK679_09080"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HPC56141.1"
                     /translation="MVGIITYGVYIPRFRIRVEEIARVWGANADDIRGGLGVYSKSVP
                     DLDEDTATIAVEAARNALRRRDIDPGAIGAVYVGSESHPYAVKPTACTVGEAIGATPV
                     MTAADYEFACKAGTAAIQTCMGLVASGMVHYGLAIGSDVAQGAPSDALEYTAAAGGAA
                     FLIGKSDPIAIIHRTCSFTTDTPDFWRREGQDYPRHGGRFTGEPGYFRHIEGASRLLM
                     EQTGKGPKDYTYAVFHQPNAKFPQRVAKMLGFSPEQIRPGLVVPALGNTYSGSSMIGL
                     AATLDQAKPGDTIFMASFGSGAGSDAFDIEVTDAIVSGDFCREAAPSVAALLANPVYV
                     DYAQYARHKGKIVMQK"
     gene            1953..3116
                     /locus_tag="PK679_09085"
     CDS             1953..3116
                     /locus_tag="PK679_09085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase domain-containing protein"
                     /protein_id="HPC56142.1"
                     /translation="MRDVAVIGIGCTPFGEKWGSSFRDLFVQAGTMALEDAGVAGEEI
                     GAMYVGNMSAGRFIEQEHVGALIADYAGLASDHIASTRVEAACASGGLSFRQAFIAVA
                     SGIEDIVVAAGVEKMTDVGTGASVDALAGAADREWEGFVGATFPGLYAMIATDYMNRY
                     PLTREQLAEVAVKNHYNGARNPIAQFSQEITIETVLSSSLVADPLRLFDCSPITDGAA
                     AVVLAPLERAREYTDTPVRVLASAQASDTIALHDRRDISTLDATVAAGKRAFAMAGLS
                     PGDIDLVEVHDCFTIAEICAIEDLGFCRKGEAGRLTAEGVTALGGDLPVNTSGGLKAC
                     GHPVGATGIKQVCEVVQQLRGEAGRRQVDGARVGMTHNVGGTGATVAVHILGV"
     gene            3120..3518
                     /locus_tag="PK679_09090"
     CDS             3120..3518
                     /locus_tag="PK679_09090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011833989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-ribbon domain-containing OB-fold protein"
                     /protein_id="HPC56143.1"
                     /translation="MSSVARFWRKIPQRYNLAGTQCTTCGRYFFPPRYLCPDCRRAGK
                     IRQHRFSGLGKVVTYTVIRSASEQFEQMTPYVLAIVELDEGPRLTAQLVCSPDEVRIG
                     MRVRPVFRRISADGESGVIHYGTKFAPENP"
BASE COUNT          646 a         1128 c         1180 g          618 t
ORIGIN      
        1 gactgcgagg agatgcggac cggcccctgg cagccaccca tgcgcgcgat gaccttgagg
       61 cactggaggt ccccgggcat aaccatgata acagaattga gatgcatact atttatggat
      121 atcccggggc gttttctttt cgtgaaatgt cgaattccca ttcgttaatt ataatacccc
      181 cgggcccgca taatgagcca tgaaatctga tttgcggaac cgcctggccg agaagatggc
      241 cggcgagatc acgctttcag actcgcccgg aaaggcactg aagaagtgga ggatgagctt
      301 caacatcccc caggcggtcc tttccgagca cctcgacgtc tccccttccg tgatttccga
      361 ctacgagagc ggaaggcgaa agagccccgg aacggctgtc gtgggcaaga tcgtggacac
      421 gatcctctcc atcgacgagg caaacggcgg gaagtacatc aagaagtttg gcaagatcct
      481 ctattctgac gttgacgacg atgtcatcta cgacatccat gactacccgt cgcccgtccc
      541 gctgacgcgg tttgccggac tgatcgcctg ccagccggtc tgcgggtcgc tttcccaggc
      601 gatttacggg tacaccgtga tcaacagcct caacgcgatc acccagctct cctcgaacga
      661 gttcaacagg atctatggct ggagcacgga gagggccctg atattcacgg acgtgacgtc
      721 cggcaagtcg ccgatggtcg cgatccgggt cacgccgttc aagccccggg ccgtcgtcct
      781 ccaggggatc gagccggccc tcgtccaccc gctcgtcccg aagatggcgg agaaggacag
      841 gatcacggtg ctctgcaccg ggatggacgt cgagcagatc gtgcatgtac tgagggagga
      901 acaatggtag gaatcatcac gtatggcgtg tacatccccc ggttccggat cagggtcgag
      961 gagatcgccc gggtctgggg tgcaaacgcc gatgacatac ggggaggact cggcgtttat
     1021 tcgaagtccg ttcccgacct tgacgaggat acggccacga tcgcggtcga ggccgcgcga
     1081 aacgccctcc ggaggaggga tatcgacccc ggcgcgatcg gtgccgtgta cgtggggagc
     1141 gagtcgcacc cctacgccgt caagcccacg gcctgcacgg tcggggaggc gatcggggca
     1201 acacccgtca tgacggcagc cgactacgag ttcgcctgca aggccggcac tgctgccatc
     1261 cagacgtgca tgggccttgt cgcgagcggc atggtccact acgggctcgc gatcgggtcc
     1321 gatgtcgccc agggagctcc ctccgacgca ctggagtaca ccgctgccgc cgggggtgcg
     1381 gcgtttctca tcgggaaaag tgacccgatt gccatcatcc accggacgtg ctcgtttacg
     1441 accgatacac cggacttctg gcggcgggag gggcaggact acccccgcca cggcgggcgg
     1501 ttcacgggcg agcccggcta cttccgccac atcgagggtg caagccggct cctgatggag
     1561 cagaccggga agggtccgaa agactacacg tacgcggtct tccaccagcc gaacgcgaag
     1621 ttcccccagc gggtcgcaaa gatgctcggg ttctcccccg agcagatccg gccgggcctc
     1681 gtcgtgcccg ccctcggcaa tacctacagc gggtcctcga tgatcgggct tgccgcaacg
     1741 ctcgaccagg caaaaccggg cgacaccatc ttcatggcgt cgtttgggtc cggggcaggg
     1801 agcgatgcgt tcgacatcga ggtgaccgat gccatcgtgt ccggggattt ctgccgggag
     1861 gctgccccct cggttgcagc gctccttgca aaccccgtct atgtcgatta cgcgcagtat
     1921 gcgcggcaca agggaaagat cgtgatgcag aaatgaggga cgttgcagtt atcgggatcg
     1981 ggtgcacacc gttcggcgag aagtggggct cttcgttccg cgacctcttc gtccaggcag
     2041 ggacgatggc tttagaggac gccggtgtcg ccggcgagga gatcggggcc atgtacgtcg
     2101 ggaacatgag tgccggcagg ttcatcgagc aggagcacgt cggggcactg attgcagatt
     2161 atgcggggct tgcctcggac cacatcgcct cgacgcgggt cgaggccgcg tgtgcctcgg
     2221 gcggtctctc cttccgccag gccttcatcg ccgtcgcctc gggcatcgag gacatcgttg
     2281 tcgcggccgg cgtcgagaag atgacggatg tcgggacggg tgcgagcgtg gacgccctcg
     2341 ccggcgctgc cgaccgggaa tgggaggggt tcgtcggggc caccttcccc ggcctctacg
     2401 cgatgatcgc aaccgactac atgaaccggt accccttaac gagggagcag ctcgcggagg
     2461 tcgccgtgaa gaaccactac aacggtgcga ggaacccgat cgcccagttc tcccaggaga
     2521 tcacgatcga gacggtgctc tcctcctcgc tcgttgccga cccgctccgc ctcttcgact
     2581 gctcgcccat caccgacggg gcagcggccg tcgtgctcgc cccgctcgaa cgggcgaggg
     2641 agtacacgga cacgcccgtc cgcgtcctgg cgagtgccca ggcgagcgat accatcgcgc
     2701 tccatgaccg cagggacatc agcacgctcg atgccacggt cgctgccggg aagagggcat
     2761 ttgcgatggc agggctctcg cccggggaca tcgacctcgt cgaggtgcac gactgcttca
     2821 ccatcgccga gatctgcgcc atcgaggacc tcgggttctg caggaagggc gaggcgggca
     2881 ggctgaccgc ggagggtgtg acggcccttg gcggagacct gccggtgaac acgtccggcg
     2941 ggctcaaggc gtgcggccac cccgtgggtg cgaccgggat caagcaggtg tgcgaggtcg
     3001 tgcagcagct ccggggcgag gcaggcaggc gccaggtgga cggggcccgc gtcgggatga
     3061 cccacaacgt cggcgggacg ggggccacgg tcgccgtcca catcctgggg gtgtgagcca
     3121 tgtcctccgt tgcacggttc tggcgaaaga ttccccagcg gtacaacctg gccgggacgc
     3181 agtgtaccac gtgcgggcgg tacttcttcc cgccccggta cctctgcccc gactgccgca
     3241 gggcagggaa gatccgccag cacaggttct cgggcctcgg aaaagtcgtg acctacacgg
     3301 tcatccggtc ggcgagcgag cagttcgagc agatgactcc ctacgtgctc gccatcgtgg
     3361 agctcgacga gggtccccgc ctgacggccc agctcgtctg cagcccggac gaggttcgga
     3421 tcgggatgcg tgtccggccg gtattccgcc ggatctctgc cgacggggag tccggcgtca
     3481 tccactacgg gacgaagttt gcgcccgaga acccgtgacg gctctctccc ggtgaagggg
     3541 gatttcttcc cctgcttttt ttccggactg tt
//
LOCUS       DAOOJU010000064         3442 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_21193_length_3442_cov_5.230883, whole genome shotgun sequence.
ACCESSION   DAOOJU010000064 DAOOJU010000000
VERSION     DAOOJU010000064.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3442)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3442)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3442
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_21193_length_3442_cov_5.230883"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            1252..3087
                     /locus_tag="PK679_09095"
     CDS             1252..3087
                     /locus_tag="PK679_09095"
                     /inference="COORDINATES: protein motif:HMM:NF012340.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HPC56144.1"
                     /translation="MFCYQPLFTYSPVTTTATPLPTVVPQLTRAPTCYDGIQNQGESG
                     IDCGGPCPPCNRCDSNYPLPDRFDWREYGIVTPIRDQSGCGSCWAFSVVAAMESNFAM
                     MTGNLNLDLSEQKFVSDYGPGMGSCCGGYHYEALDYSKSSGTVTEDCFEYQSENCGKT
                     CTPTDCDCYCTIGAYCANPCSCRYKNQTCDDIFWTLGDYGHIYEWDDPCGRGPIKRAL
                     VCKGPIVTCSPIMGHCFLLVGYDMHNSTCRQKYGKDACWIVKNSHGLLEYYNHKNIWH
                     EQGFFFYPMTSNYNAAEAQYSDLQCWAYWVSGVSRAFKAESAQGDALAVGHFGNTNRE
                     FIALALNEKDQIRLYDAVTGEIIRTFHVDNIQSGEMICAGDINGDGTDEIIYGDRDNW
                     IRVFNSRDGTLVMEFNRFRVGSRDEGFDYQEYDGLAAGDVDGDGVDEILYGSRDGDYI
                     AIIEPADRTTRKIDVGDFQKGEGIAAGDLDGDGTEEIVYGDRDDWITFYKMDGTQLAK
                     FRSDFLMHDGLAAGDMNRDGKAEVVVIHGPSNDVKVYSGTGLLLRTFKHGFEAYWSSG
                     DAAHVGDPAASGDRIAIGDVDGDGQGELVITSTGYDRVNIMEVFG"
     gene            3207..>3442
                     /locus_tag="PK679_09100"
     CDS             3207..>3442
                     /locus_tag="PK679_09100"
                     /inference="COORDINATES: protein motif:HMM:NF015827.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HPC56145.1"
                     /translation="MVNPAAAYCRELGYKIELVTQPDGSVNGICRMPDGTTINQWDFI
                     SGRSGLEWSYCTKQGLPAKHVQESTVCNDCTVCVL"
BASE COUNT          868 a          810 c          880 g          884 t
ORIGIN      
        1 gaatccctac ctgggaccga aataaacttt ttttatgatt tattaactga ttttaaacca
       61 tttcgcgaca attctaaaga ttttttgaat gattacctaa taatcaaata tgtcaactat
      121 attttacaaa aatattttta tatcataaat aatatttgca cttttgaatg ccatatgtcc
      181 ttccggtcct taccttatgg tctcgtgatt tttattttgt cttcagccct cgtgcagggc
      241 gcagtggtta tctgttcttt tcaaggatct gactcatcag ggcccctcga tctgacaact
      301 ttcaccgtgt catcgactaa tgaacaaccc cgcccgggag attctgtaac gattaccctt
      361 acttttatcc ccaatcagcc tgtaagcctt gggccaaaag ggatattcat cctcggtgag
      421 tctccctcgg gatcccagat cacgattaat tccgggtata aaggaacaag attcgagaaa
      481 ggtgagcgga taaccctcac aggaacatat tctgtaggta tagagggaac ctggaatttc
      541 tggccttctt tccaggtggt tacagcaggc tctccagctg ctggtccctc ggtcggcggg
      601 ggtgtccgct acgtcgaagc cccatactta tggcacgcct gtcaggtaat agtgaagtcc
      661 ccaccagcac catgcccgga atcgtgcagg tgcctcctgc ctgcaagtgc agatccggca
      721 ggactggtcc gatgttcgga acaaagctct ccttgcggtt actcgggaaa ccagcctctc
      781 tattgctatc ggaatgaaaa gaccgaacct caaccggttt ttattccttg cagtgatgac
      841 tgcatctgtc tccttccttc cagtgcagcc agtgcaggat acacgcgttg ttcggctcag
      901 gaccgcccct gtggccagag tatgaaccag tctctctatt gttatcaccg tccagtcacc
      961 caggttgcca gcgcaaccca gcaatgcaga agcggctgtt tctgccttct tcccgatgag
     1021 gccgaggaat caggacttgt tgcctgtgac ggccgggaaa cgatatgtgg ttactctgcc
     1081 ctccggcagc cgatgttttg ctaccagctg aatacacaaa tgaccgagag acagacaaca
     1141 caatgtaccg gcggttgtag ttgccttctg cctgccagcg caagacaggc aaattactcc
     1201 ctgtgcggag gttccgagac cctgtgcgga tactcggcaa cgcgtgaacc gatgttctgt
     1261 taccagcctt tgtttaccta ttcgccagtc acaacaacgg caacacccct cccaacggtg
     1321 gtcccgcagc ttacgcgggc acccacatgt tatgatggca tccaaaacca gggcgaatca
     1381 ggtattgact gtggcggccc ctgtccccca tgtaacaggt gtgactcgaa ctatcccctc
     1441 cccgatcgat ttgactggag agaatatggg attgtgactc ctatcaggga ccaatccggc
     1501 tgcggatcat gctgggcttt ttccgttgtt gcagcgatgg agtcaaactt tgcgatgatg
     1561 acgggaaacc ttaatcttga tctttccgag caaaaatttg tttccgatta cggtccggga
     1621 atgggttcct gctgcggagg atatcattac gaggcattgg attattcaaa aagctccggt
     1681 actgtaacag aagattgttt tgaatatcaa tccgaaaact gtggcaagac atgcacccca
     1741 acggattgtg actgttactg cacaattggg gcttattgcg caaatccctg ttcctgccgt
     1801 tataaaaacc agacgtgtga tgatattttc tggaccctcg gagattatgg gcacatttat
     1861 gaatgggatg acccctgtgg ccggggcccg ataaagcggg cactggtatg caagggacca
     1921 atcgtgacct gttctccgat catgggacac tgtttcttgc tggtgggcta cgatatgcac
     1981 aattccacgt gccgccaaaa atatggaaaa gatgcctgtt ggatagtgaa aaattcgcat
     2041 gggctattag aatattataa ccataaaaac atctggcatg aacaagggtt cttcttctat
     2101 ccaatgacct ctaattacaa tgcagccgag gctcagtata gcgacctcca gtgctgggct
     2161 tactgggtaa gcggtgtctc aagggctttt aaagccgagt ctgcgcaggg agatgctctt
     2221 gctgtcggtc acttcggaaa tactaatcgg gaatttattg cgctcgccct gaatgaaaaa
     2281 gaccagatca ggctatatga cgcagtgacc ggcgaaatta tccggacttt tcacgttgat
     2341 aacatccagt caggcgaaat gatatgtgcc ggcgatatca atggggatgg aactgacgaa
     2401 ataatctatg gtgaccgtga taactggatt agggtcttta atagtcgcga tggaactttg
     2461 gtaatggagt ttaacaggtt ccgtgtcggt tcgcgtgatg aagggtttga ttaccaggaa
     2521 tatgacggac ttgctgccgg tgatgtcgat ggtgatggag tcgatgaaat cctctatggg
     2581 tcacgtgatg gggattacat cgcaatcatt gaaccggcag ataggacaac ccggaaaata
     2641 gatgtaggtg atttccagaa aggcgaggga atagccgcag gcgacttaga tggcgatgga
     2701 acagaggaaa tcgtgtatgg tgatagggac gattggataa cattctacaa gatggatgga
     2761 acccagctgg caaaattcag atcagacttt ctgatgcatg acggtcttgc tgcaggcgac
     2821 atgaaccgtg acgggaaagc cgaggtcgtt gtcatccatg gtcccagtaa cgatgtaaaa
     2881 gtctattccg ggacgggttt actcctgagg actttcaagc atggtttcga ggcatactgg
     2941 tcttccggtg atgctgcaca cgtaggagac cccgcggctt caggggacag gatagcgatt
     3001 ggcgatgtgg atggagacgg gcagggggag ttggttatca ccagcactgg ttatgacagg
     3061 gtcaatatta tggaggtctt cggatgacga aaaacgggtt aaaatcagga aaagagggca
     3121 attacacaaa aattttcagt cgaatggcaa gggttgcttt gttccttttc attgtcggaa
     3181 tgtctcctat tagtacctgt tccggaatgg tcaatcctgc cgccgcctat tgccgtgaac
     3241 tcgggtataa gatagaactt gtcacccaac ctgatggcag tgtaaacggc atctgccgga
     3301 tgccggacgg cacgacaata aaccagtggg atttcatctc aggacggagt ggacttgaat
     3361 ggagttactg tacaaaacag ggtctcccgg caaaacacgt ccaagaatcc acagtctgca
     3421 acgattgcac cgtctgtgtc ct
//
LOCUS       DAOOJU010000065         3335 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_22076_length_3335_cov_16.251524, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000065 DAOOJU010000000
VERSION     DAOOJU010000065.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3335)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3335)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3335
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22076_length_3335_cov_16.251524"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..194
                     /locus_tag="PK679_09105"
     CDS             <1..194
                     /locus_tag="PK679_09105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013329615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56146.1"
                     /translation="TGGGVMSPAQYSSSPVPLYLLPQALSEEIRKRGDTITEVWIRRT
                     AGHTYVLRIRHAKRGDRGD"
     gene            178..540
                     /locus_tag="PK679_09110"
     CDS             178..540
                     /locus_tag="PK679_09110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56147.1"
                     /translation="MTAVTEPGTLARGGDDSLRIEAGGGSYRIEAQEVRTLLAFCRVV
                     PIIRDRHTPAAGGEKEAEPVSIEGHAAISRGGKAVLLYTRAGHFIIPVVSFSRVARGE
                     AVSAPLFPLVPDWQDGTV"
     gene            537..>3335
                     /locus_tag="PK679_09115"
     CDS             537..>3335
                     /locus_tag="PK679_09115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56148.1"
                     /translation="MTGEITKALATLFPGGGVVELRALSARGVHSGYFDDFAALAEKA
                     ANLDVLPDVGGVYVTLNEVDPALLSRRANRVQMDIGRKDPTTGDSDVLRRRWLPVDLD
                     PVRPSGVSSTDAEHEAALARAREIAAFLGQEAGWPDPVIADSGNGAHLLYRIDLPNDG
                     ESADLVKACLAVLDTLFSDGVVSVDAANYNAARIWKLYGTAAKKGDNTASRPHRQSRL
                     LSVPGRVQAVPAGLLRRLAGLLPQADPGRGRPAKGPGIDLREWLPAHGIAVRSEKPWQ
                     GGTLFVLEECPFSSAHRDGAFAIQFPSGALYAGCKHDSCGGGRQRWQELRDRSGRHRR
                     EKRVDGPSPAAGVAPPPPSAAEAEARARAEEILRSGDPLGFLLSVFSREHVGDRMVAE
                     CLVLSIASQSVENTQGLHVAISGNSGKGKTHACRAMLNLLPPRFRLKGTVSDKALYYH
                     AVQPGTVLLFDDVWLSDDLQEVLKAATANFREPIEHRTLTSDRQVRVCTIPPRCVWWL
                     AKVEHAGDDQVMNRMLCAWIDDSADQDAAVLAHLKDREAKPAGDGEDADVLAARAMWE
                     IIKEEVLHVRVPFAPRVHFSATRNRRNPGMLFDLLKCHARLFFLQRERDAGGSIVANR
                     EDFAYARRLFIELSSETGAQDTKQTRTEAAALETIAKMGLEVFSIRQLQEALGLSYYQ
                     AYRLLKGYRNGHGSYPGILDKCPAVSYIDAIVSEEISGREVKHREHYFSFDIAAFRKW
                     TARPEIWLEDEAAGVTPGDGGQGPDICTFAPGLHPGGANAQGAGSGPGSGNGDSGTGR
                     KTPPCPSLHHLQEEQSTTGEPGSGSAVPCVPAKGANVSAEPAGKSPITVPDVQDGSHV
                     CTGGCKDVLTCSHGAKVTKPFRVDPLPGLLDHRDFRRVQSDLGRCDICNGGKAVFWCA
                     EKRVGVCERCYGRLLGEWN"
BASE COUNT          540 a         1124 c         1158 g          513 t
ORIGIN      
        1 tcaccggagg tggcgtgatg tccccggcac agtactcgtc gtcgccggtc ccgctctacc
       61 tcctaccgca ggccctctcg gaagagatca ggaagcgggg ggacaccatc accgaggttt
      121 ggatccggcg gaccgccggc cacacctacg tcctgcggat ccggcacgca aagcggggtg
      181 accgcggtga ctgaacccgg caccctcgca cggggcgggg acgattccct ccggatcgag
      241 gccgggggcg ggtcctaccg gatcgaggca caggaagtcc ggacgctcct tgccttctgc
      301 agggtcgtcc cgatcatccg ggaccggcac acaccggccg ccgggggaga aaaagaggct
      361 gaaccggtct ccatcgaggg ccacgcggcc atcagccggg gcggaaaggc agtcctcctc
      421 tacacccggg ccggccactt catcatcccg gtcgtgagct tttcgcgggt ggcccggggc
      481 gaggcggtct cggccccgct cttccccctc gtccccgact ggcaggacgg gacggtatga
      541 ccggggagat cacaaaggcc ctcgcgacac tctttcccgg cggaggggtc gtggaactgc
      601 gggcgctctc tgcccgcggc gtccattccg ggtacttcga cgacttcgct gccctcgcgg
      661 aaaaggccgc aaacctcgac gttctcccgg acgtcggggg cgtgtacgtc accctcaacg
      721 aggtcgaccc tgccctcctc tcgcggaggg ccaaccgggt ccagatggac atcgggcgga
      781 aagacccgac cacgggcgat tccgatgtcc tccgcaggcg gtggctcccg gtcgacctgg
      841 accctgtccg gccgagcggc gtctcctcga cggacgcgga acacgaagca gcactcgccc
      901 gggccaggga gattgccgcg ttcctcgggc aggaggcggg gtggcccgac ccggtcatcg
      961 ccgattcggg gaacggtgcc cacctcctct accgcatcga ccttcccaac gacggggagt
     1021 ccgcggacct cgtgaaggcg tgccttgcgg tcctcgacac gctcttttcg gacggcgtcg
     1081 tgtccgtcga tgccgcgaac tacaacgcgg cccgcatctg gaagctctac gggacggccg
     1141 cgaagaaggg cgacaacacc gcttcccggc cgcaccggca gtcccgcctc ctctccgtcc
     1201 ccggcagggt gcaggcggtt ccggccggcc tgctccgccg tctcgccggg ctgctcccgc
     1261 aagccgaccc gggccggggg cggccggcaa agggtccggg catcgacctc cgcgagtggc
     1321 tcccggccca cgggatcgcg gtccggtccg agaaaccgtg gcagggcggg accctgtttg
     1381 tcctcgagga gtgcccgttc tcgtcggccc accgggacgg ggcgttcgcg atccagttcc
     1441 cgagcggagc cctgtacgcc ggctgcaagc acgactcctg cggcgggggg aggcagcggt
     1501 ggcaggagct ccgcgaccgg tccgggcggc accggcggga gaagagggtg gacgggccgt
     1561 cccccgcggc tggagtggcc cctccccctc cgtccgcggc agaggcggag gcccgggccc
     1621 gggcagagga gatcctgcgg tccggcgacc cgctcgggtt cctcctctcc gtcttttccc
     1681 gggagcacgt cggggaccgc atggtcgccg agtgcctcgt gctctcgatc gcatcccagt
     1741 cggtggagaa cacgcagggc ctgcacgtcg ccatctccgg gaactcggga aagggcaaga
     1801 cgcacgcctg ccgggcgatg ctcaacctgc tgccgccccg gttcaggctg aagggaacgg
     1861 tctcggacaa ggccctgtac taccacgcgg tgcagccggg aaccgtgctc ctcttcgacg
     1921 acgtctggct ctccgacgac ctgcaggagg tgctgaaggc ggcgaccgcg aatttccggg
     1981 agccgatcga gcaccggacg ctgacgagcg accggcaggt ccgggtctgc acgattcccc
     2041 cgcggtgcgt ctggtggctg gcaaaggtgg agcatgccgg ggacgaccag gtcatgaacc
     2101 ggatgctctg tgcctggatc gacgattcgg ccgaccagga cgcagcggtc cttgcgcacc
     2161 tgaaggaccg cgaggcaaag ccggccgggg acggggaaga cgccgacgtc ctcgctgccc
     2221 gggcgatgtg ggagatcatc aaggaggagg tcctgcacgt ccgcgtcccc ttcgccccgc
     2281 gggtccattt ctcggcaacc cggaaccggc ggaacccggg gatgctcttt gacctgctca
     2341 agtgccacgc gaggctcttt ttcctccagc gggaacggga cgccggcggg agcatcgtcg
     2401 cgaaccggga ggacttcgca tacgcccgca ggctctttat tgagctctcg agcgagaccg
     2461 gggcgcagga tacgaagcag acccggacgg aggctgcggc cctcgagacc atcgcgaaga
     2521 tgggccttga ggtcttttcc atccggcagc tccaggaggc gctcgggctc tcgtactacc
     2581 aggcctaccg cctcctgaag gggtaccgga acggccacgg gtcctatccc ggtatcctcg
     2641 acaagtgccc ggcagtcagc tacatcgacg cgatcgtcag cgaggagatc tccgggcggg
     2701 aggtgaagca ccgcgagcac tacttctcgt ttgacatagc ggccttccgg aagtggacgg
     2761 cccggccgga gatctggctc gaggacgagg ctgccggggt tacaccaggg gacggtggtc
     2821 aggggcccga tatttgcacc tttgcacccg gtttgcaccc gggaggtgca aacgcacaag
     2881 gggcgggatc cggccccgga tcgggaaacg gtgactccgg taccgggaga aagacacctc
     2941 catgtccctc tttgcaccat ttgcaggaag agcagagcac gaccggagag ccgggcagtg
     3001 gttctgccgt cccgtgcgtt cctgcaaaag gtgcaaacgt ctccgcggaa cccgcgggta
     3061 agtccccgat cacggttccg gacgtgcagg atggttccca cgtttgcacc ggcgggtgca
     3121 aggatgtgct aacgtgctcc catggtgcaa aggtcaccaa gccgttccgc gtggaccccc
     3181 tgcccggtct cctcgatcac cgtgacttca ggcgggtcca atcggacctt ggccggtgcg
     3241 atatctgcaa cgggggaaag gcggtcttct ggtgtgcgga gaaacgggtc ggtgtgtgcg
     3301 agaggtgcta cgggaggctg cttggggagt ggaac
//
LOCUS       DAOOJU010000066         3328 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_22149_length_3328_cov_14.765658, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000066 DAOOJU010000000
VERSION     DAOOJU010000066.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3328)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3328)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3328
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22149_length_3328_cov_14.765658"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(92..994)
                     /locus_tag="PK679_09120"
     CDS             complement(92..994)
                     /locus_tag="PK679_09120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013330266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC56149.1"
                     /translation="MIQVAVLSGKGGTGKTVVTGALAEFLPGKKVFADCDVEAANLAL
                     ILSPRERARIPFFGLKKATIEKKSCVACGLCAHACRFGAIRNGIDGSFYVDPVRCEGC
                     GVCAGVCPERAIVLRKKQDGEIICADTDLGPLVYAELSPGSGNSGLLVHEVKKEAQKE
                     VRDHDLLLIDGPPGIGCPVISTMSGIDTVVIVTEPSIAAMHDLKRLVMVSRGFSLSLC
                     AIINRADLHGGYAQTIERFCADEGISLLGKVPFDPTVQDAVSKGVPVTRFGCPATAAF
                     REIAANLSGILGEKASDRLKGRNE"
     gene            complement(991..1842)
                     /locus_tag="PK679_09125"
     CDS             complement(991..1842)
                     /locus_tag="PK679_09125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011845257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HPC56150.1"
                     /translation="MRVVVASGKGGTGKTLVAANLAAVVACLCDVVLVDCDVEEPNLH
                     LFFPSEKKLLPVLADVPVFDTVRCDHCGECARTCQYGAIVVLSQKNLFFPEMCHGCGG
                     CEIVCPQGAITMGKREVGRIEFSRPRAGLTLVSGVLNEREVAAPRVIREALRYAAGHP
                     LVICDAPPGTACPLVETLEGADFCILVTEPTPFGLHDLSLAAGVAGVLGVPAGVVINR
                     SIGEDEIIWRFCRSENIPVLWTIPFEKRIAELANEGKVLTDEIPEMKELFIRLFAEVR
                     HRGEAGL"
     gene            complement(1852..2187)
                     /locus_tag="PK679_09130"
     CDS             complement(1852..2187)
                     /locus_tag="PK679_09130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004038912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HPC56151.1"
                     /translation="MIICITSKGPKSTDPVEERFGRSPYFLFHDTEKGDFDPVTNKFA
                     DAAGGVGPRAAQVLIDRGAKVLITGNVGGNALSVIQAAGIEVFRYRDGGSVEDAFQKY
                     QKGLLGKMA"
     gene            2351..3292
                     /locus_tag="PK679_09135"
     CDS             2351..3292
                     /locus_tag="PK679_09135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC56152.1"
                     /translation="MKYMHIFGPVASRRLGRSLGIDLVPHKVCSFDCVYCEVGRTTLK
                     TISRQEFFPPEEVECELFTFLSSRPDLDFITFSGSGEPTLSLSIGRVIRFIKDTFPGY
                     RVAVLTNGSLLGNGDVQDALRPADVVLPTLSTVDEETFQKIHRPVAGVSVRAIIEGLC
                     RFRETYPGEIWLEVFLVPGLNTGDDALYALKEVIGRIRPDRVQLNTLDRPGPEPRVRA
                     AGTGDLQRAARILGIGEEEAFLPLRYGEVHGRPPEDAQSVIIEAIRRRPGTLEDLVAL
                     TGLHRQEVIKLLRALSVDPRLKTRREARGTFYSWSGD"
BASE COUNT          696 a         1025 c          901 g          706 t
ORIGIN      
        1 cactggaatc atccggaatg gttgattttt cccgggcggg tgaagcggcc cggggatcag
       61 gagacgcggg actcttccgg caaccccccg ttcattcatt ccggcctttc aaacgatccg
      121 aagccttttc tccgagaatt cctgaaagat tcgctgctat ttcgcggaat gcggctgttg
      181 caggacatcc aaaccgcgtg acaggcaccc ccttactgac tgcgtcctgg acggttgggt
      241 cgaaggggac ctttccgagt agggatatcc cttcgtctgc acagaacctc tcgatcgttt
      301 gtgcataccc tccgtggagg tcggccctgt tgatgatggc acacagggag agagaaaaac
      361 cacgtgagac cataacgagt cttttgaggt catgcatcgc cgcgatactt ggttccgtga
      421 cgatgaccac ggtatctatt ccgctcatcg tcgagatgac agggcacccg ataccggggg
      481 gtccatcgat caggagaagg tcgtgatccc ggacttcctt ctgcgcctct tttttcacct
      541 cgtggaccag aagaccggag ttgcccgaac cgggactcaa ctccgcatac acgagaggcc
      601 caaggtccgt atccgcacaa ataatctcac catcctgttt cttccgaaga acaatcgctc
      661 tctcggggca gacgcccgca cagacaccgc acccctcgca acggaccgga tcgacataaa
      721 aggaaccatc gatcccattc ctgattgcgc cgaagcgaca tgcatgtgcg cagagtccgc
      781 aggcaacaca cgactttttc tctatcgtgg ctttttttag tccgaaaaag gggatacggg
      841 ccctttcgcg tggtgagagg atgagagcaa gatttgcggc ctccacgtca caatcagcaa
      901 ataccttctt tccaggcagg aactctgcaa gggcacctgt cacaacggtc ttgccagtac
      961 cacctttccc ggagaggact gcaacctgta tcataaaccc gcctcacccc ggtgtcggac
     1021 ctccgcaaag agcctaatga aaagttcctt catctccgga atctcgtccg taaggacctt
     1081 cccttcgttt gcaagttctg ctatccgctt ctcaaaggga atcgtccaga gcaccgggat
     1141 gttttccgaa cggcagaacc tccatataat ctcgtcttct cctatactcc ggttgatgac
     1201 gacacctgcc gggacaccga gaaccccggc cacccctgca gcaagggaga ggtcgtggag
     1261 gccaaagggc gtcggttccg tgacaaggat gcagaaatcc gctccctcca gggtctcgac
     1321 gagcgggcat gccgttcccg gcggtgcatc gcagatgacg agcgggtgac ctgccgcata
     1381 gcgtagtgcc tcgcggatga cgcggggtgc tgcgacctct ctttcgttca gaacgccgga
     1441 gacgagggtg agaccagccc ggggcctgga aaattctatc cttcccactt ccctctttcc
     1501 catcgtgatg gccccctgcg gacagactat ctcgcagccc ccgcacccgt gacacatctc
     1561 ggggaagaaa agattctttt gcgacagaac gacgatggcc ccgtactggc aggtccgcgc
     1621 acattccccg caatggtcgc accggaccgt atcgaatacc gggacgtctg ccagcacggg
     1681 cagcagcttt ttttccgagg ggaaaaacag gtgcaggttc ggctcttcga cgtcacagtc
     1741 gacgagcacg acgtcgcata aacaggcaac cacggctgcc aggttcgctg caacgagggt
     1801 ctttcccgta ccccctttcc cgctggcaac cacgacccgc atcctgcact cctacgccat
     1861 cttcccgagg agtcctttct ggtacttctg aaacgcgtct tctaccgatc cgccatccct
     1921 gtaccggaac acctcgattc cggcggcttg gatcaccgaa agggcattcc ccccaacgtt
     1981 cccggttatc aggacctttg cgccgcgatc tatcaggacc tgtgccgcac gcgggccgac
     2041 accgccggct gcatcggcga acttgtttgt gacaggatca aagtcgcctt tttccgtgtc
     2101 atgaaagagg aaatagggtg atctcccaaa ccgctcttcc acaggatccg tggacttcgg
     2161 acctttggac gtgatgcaga taatcatgat gagttatttt actcatatga gcataaatag
     2221 atagagatgg tacattccca ccggtacacc ccggaacaga accacttgaa aagagaccat
     2281 gctcaggtac atctcatctc gttgattgtg atgaggatca cccgcaaaac cggtccatcc
     2341 cacgattgcc atgaagtata tgcacatctt cggccctgtt gcgtcccggc gcctcggtcg
     2401 ttccctcggc attgaccttg tcccccacaa ggtctgttcc tttgattgcg tgtactgcga
     2461 agttggccgg acaaccctga agactatttc ccggcaggag ttcttcccgc cggaagaggt
     2521 cgagtgtgag ctgttcacgt tcctttcctc acggccggac cttgatttta ttaccttctc
     2581 gggatcgggc gagccgacgt tgtccctctc tatcgggagg gtgatccgct tcatcaagga
     2641 cacctttccg ggttacaggg ttgcagttct cacaaacggg agcctgcttg ggaatggcga
     2701 tgtccaggat gcgctgcgcc cggccgacgt ggttctaccc acactctcga cagtcgatga
     2761 ggagacgttc cagaaaatcc acaggcctgt ggcgggggtc tctgtccgcg ccatcatcga
     2821 gggactgtgc cggttccggg agacgtatcc cggggagatc tggctcgagg ttttccttgt
     2881 tcccggcctc aacacgggag acgacgccct gtatgccctc aaggaagtga tcgggaggat
     2941 acggccggac agggtgcaac tgaacaccct cgaccgtccg ggaccggaac cccgggtccg
     3001 tgcggcaggc accggtgatt tgcaacgggc tgcccgcatc cttggtatcg gagaagagga
     3061 ggcatttctc ccgctccggt atggggaggt ccatggtcgg cccccggaag atgcacaatc
     3121 cgtcatcatc gaggcgatca ggaggcgccc gggtactctc gaagacctcg tggccttaac
     3181 ggggttgcac cgccaggaag tgatcaagct tctccgcgcc ctttccgtcg atccccgcct
     3241 gaaaacacgc cgggaagcaa gaggcacctt ctactcctgg tccggggact gacgatcaga
     3301 ccagcgtata atccgtgagc cgctgccg
//
LOCUS       DAOOJU010000067         3258 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_22788_length_3258_cov_14.476116, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000067 DAOOJU010000000
VERSION     DAOOJU010000067.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3258)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3258)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3258
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_22788_length_3258_cov_14.476116"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(52..1023)
                     /locus_tag="PK679_09140"
     CDS             complement(52..1023)
                     /locus_tag="PK679_09140"
                     /inference="COORDINATES: protein motif:HMM:NF012568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HPC56153.1"
                     /translation="MTSLHPFPEIHEDLMVVEDILLSLPREAGVPVEDILSGAIPGGK
                     RIRPSVVLLAGRMLGGPRRSLLEIAAAIEMIHIGTLVHDDIIDSVPRRRGHDSLHTLW
                     GVSPAVLAGDFLLSAGLGRVASLGDPGLVSVLTDAVCSVCRGEIRELANIGRTGTKRE
                     EYFRVVGEKTASLFSAGMVMAGMVSGAGNETLYALENSGRLLGTAFQLVDDIADITGD
                     ERVTGKVPGTDLRRGIVTLPVIIFAEMQGNRCIPEPLCRGNPDEDAVRDICREIRASG
                     AIEECQKAAGEIAMETRKLLASFPDNCYREALDRLAQEIVGPPEHGQ"
     gene            complement(1020..2201)
                     /locus_tag="PK679_09145"
     CDS             complement(1020..2201)
                     /locus_tag="PK679_09145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HPC56154.1"
                     /translation="MPPTLPARQFFSAFLMALLTGWKFFPSWMARHGTRCVPGASGAL
                     GMGCIGFPNHPVWEVTSRCNLDCIHCHARGSRQNGPELSTSEGLALLDELAKIPGFRM
                     VAFTGGEPLVRDDLFSLLAHAKSLGFSGTIATNATLVDFPTARKLRDNGIAIAAVSLD
                     GCDPAAHDSVRGVRGSFDAAIEGIHAINRAGIPLHINITVMNRNRERLGEIMELANQL
                     KAAIIIIYQMVPVGRGRKMGEPTPGTAGHADLVRFIAGAQSGSRAIIEPVAAPQYWAH
                     LLERNTILPTVALRLAGHLFFGCCAGRGFIYVKPDGEVWPCPFLEVSCGNTRDTPFSE
                     IWKSSPVLARLRERALRGKCGSCRYQAVCGGCRGRAYVMTGDFMQEDPFCFIKAERDD
                     R"
     gene            complement(2234..3136)
                     /locus_tag="PK679_09150"
     CDS             complement(2234..3136)
                     /locus_tag="PK679_09150"
                     /inference="COORDINATES: protein motif:HMM:NF013226.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HPC56155.1"
                     /translation="MSAWWALSRPPFHLTGLLPFLLGTVMAWSFPGTLRWDILLWGCA
                     GVVLVMLSTYYAGEYWDIVEDRIAGERGKSRFSGGSGMVPGGQVKRKQVIAAAVACLL
                     LALLVGFILTFLYGCGPLTIPFGLLGITGGFLYSARPVRWVSRGIGELWIALCYGWLP
                     VVTAFYLQRGTIPAMVHVVTLPLAFSVFSVILLNEFPDYDADRIAGKTNLLVRFGHRS
                     GESMFILALVSAWVSFFSIAVHYGFPVPVLVGIPFLAVSAVIIDTVMKSPWEDRKKVE
                     RLCGANILVNMGITFSLIAGFLSW"
BASE COUNT          743 a          948 c          942 g          625 t
ORIGIN      
        1 ttcatttcct gtcaaaaacc aggagagcac cccctttctc gaaaaaagaa attattgacc
       61 gtgctcgggg ggccccacaa tctcctgtgc cagcctgtca agtgcttccc ggtaacagtt
      121 atcggggaat gatgcaagca atttcctggt ctccatcgcg atctctcccg ctgctttctg
      181 gcattcctcg atcgcacctg atgcacggat ctcccggcag atatcccgga ctgcgtcctc
      241 gtccgggttg ccccggcata acggttcggg gatgcagcgg ttgccctgca tctctgcgaa
      301 gatgatgacc gggagggtga cgatcccgcg gcggagatcc gtgcccggga ccttcccggt
      361 aaccctctcg tccccggtga tatcggcaat gtcgtccacc agttggaacg cagtcccgag
      421 cagtctccct gaattttcca gtgcatacag tgtctcattg cctgcaccgg ataccatccc
      481 tgccatgacc atgccggcag aaaagaggga ggcggtcttt tccccgacga ccctgaaata
      541 ttcctcccgc tttgtccctg ttctgcctat attggccagt tcacgtatct ctcccctgca
      601 aacgctgcat acggcatcgg tgagtacaga aacgagtccg ggatcgccga gggatgcgac
      661 ccttcccagt cccgctgaaa ggagaaagtc cccggcaagg accgcaggag agactcccca
      721 gagcgtatga agggaatcgt gacccctccg gcgcggtaca gagtcgatga tgtcatcgtg
      781 gacaagcgtc ccgatatgga tcatctctat cgctgccgcg atctcgagga gggatcgacg
      841 gggtccgccg agcatcctgc ccgcgaggag gacgacagag gggcggatcc tttttccccc
      901 gggaatggca ccggagagga tgtcttccac cgggacacca gcctcccggg gaagggagag
      961 gaggatatcc tcgacgacca tgaggtcttc atgaatttca ggaaacgggt gaagggatgt
     1021 catctatcat ccctttcggc ttttatgaaa cagaaggggt cttcctgcat gaagtctccg
     1081 gtcatcacgt atgccctgcc cctgcacccg ccacagaccg cctggtaccg gcatgacccg
     1141 cactttcccc ggagggctct ctccctcagg cgggcaagga cgggagatga tttccatatc
     1201 tctgagaacg gggtatcgcg ggtattccca caggaaacct cgaggaaggg acacggccag
     1261 acttcaccgt ccggtttgac gtagataaaa cccctgcctg cacagcagcc aaagaacagg
     1321 tgccctgcaa ggcggagcgc gacggtggga aggatggtgt ttctttcaag gaggtgagcc
     1381 cagtactggg gtgctgcgac cggttcgatg atcgccctgc tgcctgactg ggcacctgca
     1441 atgaaccgga cgaggtctgc atgacctgcg gtgccggggg tcggttctcc catcttcctt
     1501 cccctgccga ccggaaccat ctggtaaatg atgatgatgg cggctttgag ctggttggcc
     1561 agttccatga tctcccccag cctttccctg ttcctgttca tgacggtgat gttgatgtgg
     1621 aggggaatac ccgcacggtt tatggcatgt attccctcga ttgccgcatc gaatgaacct
     1681 ctcacaccgc ggacggaatc gtgggctgcc gggtcacacc cgtcgagact gacggccgca
     1741 atcgcaatgc cgttatcccg tagctttcgt gccgtgggaa agtcaacgag cgttgcattg
     1801 gtcgcaatcg tccccgaaaa accaaggctt ttggcatgtg caagcaggga aaagagatcg
     1861 tccctgacaa gcggttctcc gccggtgaat gccaccatcc tgaacccggg tattttggcg
     1921 agttcatcga gaagtgccaa tccctcggac gtggagagtt ccgggccgtt ttgccgggaa
     1981 ccccgggcat ggcagtggat acagtcgagg ttacaccggc tcgtcacctc ccagacaggg
     2041 tgattgggaa aaccgatgca tcccattccc agggcacccg atgctcccgg aacgcaccgg
     2101 gtaccgtgcc ttgccatcca ggaagggaag aacttccacc ctgtcaggag ggccatcagg
     2161 aatgcagaga aaaactgcct ggccggaagc gtagggggca taaagaaagg cgcaaccggc
     2221 cctgacccct tttttaccat gagaggaacc ccgcgatgag ggagaacgtg attcccatgt
     2281 tgacgaggat gtttgcacca cagaggcgct cgaccttctt cctgtcctcc cacggtgact
     2341 tcatgaccgt gtctataatg acagcagaaa cggcaaggaa cgggattccc accaggacag
     2401 gaacaggaaa accatagtgg actgcaatgg aaaagaaaga gacccatgcg gagacgagag
     2461 cgaggatgaa catggattct ccggatcgat gcccgaatcg cacgaggagg tttgttttcc
     2521 cggcaatcct gtccgcatcg taatccggga actcgttgag gaggataaca gaaaaaacgg
     2581 agaatgcgag gggaagagtg acaacgtgga ccatggcagg aatcgtgccc cgctggagat
     2641 aaaacgcggt tacgaccgga agccatccat agcagagtgc aatccacaat tcaccgatcc
     2701 ccctgctcac ccagcgcacg gggcgggcag agtagaggaa tccccccgtt attcccagga
     2761 ggccgaatgg aatcgtcagc ggtccgcaac catagagaaa agtcagtatg aacccgacga
     2821 ggagggccag caggagacat gcgaccgctg ctgcaatgac ctgcttcctt ttcacctgcc
     2881 ctcccgggac catgccggag cctcccgaga acctcgactt tcccctttct cctgcaatcc
     2941 gatcttcaac gatatcccag tattcacccg catagtacgt cgagagcatc acgaggacaa
     3001 caccggcaca cccccagagc aggatgtccc accgcagcgt ccccgggaaa gaccatgcca
     3061 taacggtccc gaggagaaag ggaagaagtc cggtgaggtg gaaagggggt cttgacaggg
     3121 cccaccatgc agacattctc cgtgagaggt gaggcagaac ggcaggtgca gtttccggaa
     3181 gacgaaaggc cacgggaggt tttttagtga gaatccgctt aaagattacc ctgcacgggg
     3241 agaggaacgg gacagggg
//
LOCUS       DAOOJU010000068         3107 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_24204_length_3107_cov_4.573067, whole genome shotgun sequence.
ACCESSION   DAOOJU010000068 DAOOJU010000000
VERSION     DAOOJU010000068.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3107)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3107)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3107
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_24204_length_3107_cov_4.573067"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..647)
                     /gene="mcrG"
                     /locus_tag="PK679_09155"
     CDS             complement(<1..647)
                     /gene="mcrG"
                     /locus_tag="PK679_09155"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     gamma"
                     /protein_id="HPC56156.1"
                     /translation="MARKPQFGPGTSIVAENRRRQMDPSRRLPIVRNVTEEDIVLLLG
                     HRAPGSAYPSAHPPLAEQQEPDCPMRKLVSPTEGAKAGDRVRYIQFADSMFNAPCQPY
                     QRTYVEMYRFRGIDPGTLSGRQIVECRERDLEKYSKELIETDLFDPARSGLRGATVHG
                     HSLRLSEDGMMFDALQRCILDRDGIVKYVKDQVGVPLDRPVSVGKPMDEDWLKRKS"
     gene            complement(648..1139)
                     /gene="mcrD"
                     /locus_tag="PK679_09160"
     CDS             complement(648..1139)
                     /gene="mcrD"
                     /locus_tag="PK679_09160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-coenzyme M reductase operon protein D"
                     /protein_id="HPC56157.1"
                     /translation="MTDVLEFPQCRIVPMRLLGADTTRRLLDRLATVHGVRRILLNGQ
                     NLPSTVPYGPSRGLATVHPQRKKIRVLGTEVDLRVQVGSLVLEVEDRSVIDEVRSLCG
                     DFFTDFSCSVQEGRFMKTRPSLSDYARYGPLPDPAMIGLSDPKQKEDPVFLTEPTGCR
                     GDL"
     gene            complement(1143..2447)
                     /gene="mcrB"
                     /locus_tag="PK679_09165"
     CDS             complement(1143..2447)
                     /gene="mcrB"
                     /locus_tag="PK679_09165"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     beta"
                     /protein_id="HPC56158.1"
                     /translation="MTRYQETIDLYTDDGRLLKSNVFLHRINPLINPAALQIIDLTKR
                     TINVNLGGIEDALKTAKLGKRKIPGRELKLPIMERKDEIIDKIRSMVQVTEDDDTEVM
                     QFAGGKLLLVRVPTQRLTGASTYDAAITAVASAVTYAIVDTFDVGPFDASTVKAACWG
                     SYPHTQDMEGALVTSILTIPQNNEGIGYALRNINVNHFVMMTNRNALQGTALSATLET
                     AGIFEMGGAIGPFERNQLLCYAYQGLNANNMVYDIVKENGRSGTVGTVVQSLVDRAVE
                     DRVIFPGKKGAYFQFYDTKDPMLWNAYACAGTLAATIVNCGAGRFVQAVSSTLLYFND
                     LLEHETGLPGADFGRVMGTAVGFSFFSHSICGGGGPGVFNGNHVVTRHAYGVAIPCVV
                     AAAAMDAGTQMFSPEATSRIMGETYGKIDVFSRPLHQIAMGA"
BASE COUNT          647 a          864 c          891 g          705 t
ORIGIN      
        1 gacttccgtt tcagccaatc ctcgtccatc ggttttccga cgctgactgg acggtcgagg
       61 ggaacaccca cctggtcctt gacgtacttg acgattccgt cccggtcgag gatgcatctc
      121 tggagcgcat cgaacatcat cccgtcttcg gagagtcgca gggaatgacc gtgcacagtg
      181 gcccccctga gacctgaacg cgcgggatcg aacaggtcgg tctcgatgag ttccttggag
      241 tacttttcaa gatcccgctc ccggcattcg acgatctggc gtcccgaaag ggtgccgggg
      301 tcgatcccgc ggaacctgta catctccacg tacgtccttt gatagggctg gcagggcgca
      361 ttgaacatcg aatctgcgaa ctggatgtac cgtacacggt cccctgcctt tgcaccctcg
      421 gtcggggaca cgagcttgcg catcgggcag tccggttcct gctgctcggc cagcggggga
      481 tgcgcactcg gatacgccga accgggtgca cggtggccga ggaggaggac gatatcttcc
      541 tctgtcacgt tcctgacgat ggggaggcgt ctcgaaggat ccatctgcct cctgcggttc
      601 tcggcgacaa tggacgtgcc gggaccgaac tggggtttcc gggccattca gagatccccc
      661 ctgcaacccg ttggctcggt caggaaaacc gggtcttcct tttgtttcgg gtcggacagg
      721 cctatcatcg cgggatcagg caacggcccg taccgggcat aatctgaaag gctgggcctt
      781 gttttcatga acctgccctc ctgcacggag catgaaaaat cggtgaaaaa gtccccgcag
      841 agggaccgga cttcgtcgat gacagacctg tcttcaactt cgagtacgag gctccccacc
      901 tgcacccgga ggtcgacctc ggtaccgagg acgcgtattt ttttccgctg ggggtggaca
      961 gtggcgagtc cccgtgacgg gccatagggc acggtcgagg gaaggttctg accgttgagg
     1021 agaatcctgc gcacaccgtg gactgtggca agcctgtcga ggagacgcct cgttgtatcg
     1081 gcaccaagga gccgcatcgg gacgatccgg cactgaggga attctaaaac atctgtcatt
     1141 tttcaggccc ccatcgctat ctggtggagc ggccgggaga aaacatcgat tttgccgtaa
     1201 gtctcgccca tgatccttga cgtcgcttcc ggcgagaaca tctgggtgcc ggcgtccatg
     1261 gcagcggcag cgaccacgca cgggatggcc acaccgtatg catggcgggt gacaacatgg
     1321 ttgccgttga agactccggg gccgccaccg ccacagattg aatggctgaa gaacgagaac
     1381 ccgactgcag tccccatgac ccgtccgaaa tccgcccccg ggagcccggt ctcatgttcg
     1441 aggagatcgt tgaaatagag gagtgtcgaa gagactgcct gcacgaaacg gcctgccccg
     1501 cagttcacga tggttgctgc cagcgttccg gcacatgcat aggcattcca gagcatcggg
     1561 tccttcgtgt cgtagaactg gaaatacgcc ccctttttcc cggggaatat gaccctgtcc
     1621 tcgactgccc ggtccacgag ggactgcacg acggtgccca cggttcctga ccggccattc
     1681 tccttcacga tatcgtacac catgttattg gcattgaggc cctggtatgc atagcagagg
     1741 agctggtttc gttcgaaagg cccgattgca ccccccatct cgaagatccc cgcggtctcg
     1801 agggttgcgg agagtgcggt cccctgcagg gcattcctgt ttgtcatcat gacgaaatgg
     1861 ttgacattga tattgcggag cgcgtatcca atcccctcgt tgttctgggg gatggtgagg
     1921 atcgacgtga cgagtgcccc ttccatgtcc tgggtgtggg gataactgcc ccagcatgct
     1981 gccttgacgg tggatgcatc gaacggaccg acatcgaagg tgtcgacgat agcataggtc
     2041 actgcggatg caaccgccgt gatcgcagca tcgtacgtgg aagcacctgt cagcctctgt
     2101 gtgggtaccc tgacgaggag gagttttcct ccggcgaact gcataacctc ggtatcgtca
     2161 tcctccgtga cctggaccat cgaccgaatt ttatcgatga tctcatcctt tctttccatg
     2221 atgggcagtt tgagttcccg cccgggaatc tttctctttc cgagttttgc agtcttcaaa
     2281 gcatcctcga tcccaccaag gttcacattg attgtcctct tggtcaggtc gatgatctgg
     2341 agagctgcag ggttgatgag ggggttgatg cggtgaagga acacgttgct cttcagcagg
     2401 cgcccatcat ctgtgtagag atcgattgtc tcctggtatc gcgtcatact gtccgaaacc
     2461 tcttttatcc ggtttttgga agactgcatg gcatggtgcc accatgcctg aaggatagcc
     2521 atctggtatt accttcattc cataaaatat caaaaaatta ctattaatac tataaagtgt
     2581 atactaattt acttactatg ccaaagcata gtgatacgac atgcaggtgc tgtctccgcg
     2641 aaataatgcc ggtcctctca cggaagtggt ccatatgcgt aattgccacc ctgggacggc
     2701 acggcaggat gaggttttcc gagattctgc tggtgtgcag gacaatatct ccccgttccc
     2761 tcacgatagt actgcaggat cttcaggaac atggaattgc tacaagacag tccttcccgg
     2821 agatacctcc ccgcgtggaa tattccctta cgacaaaggg aatggcactc tggaaatctc
     2881 ttgttcccct tttttactgg gccagggaat atcaccgtca tgttgatgaa caaccgggga
     2941 tgctctgttt ccaggcacct gacctgtgat agggtaatac gaatcgggaa aggaaattaa
     3001 cgttgttcag gcggcaacag ggacaaaaac aagagattgg ggggacgaaa agcccccccg
     3061 gggacgggca gttggactgt gctggttggt ggaccggtca aaactct
//
LOCUS       DAOOJU010000069         3032 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_25028_length_3032_cov_4.879745, whole genome shotgun sequence.
ACCESSION   DAOOJU010000069 DAOOJU010000000
VERSION     DAOOJU010000069.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3032)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3032)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3032
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_25028_length_3032_cov_4.879745"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..292)
                     /locus_tag="PK679_09170"
     CDS             complement(<1..292)
                     /locus_tag="PK679_09170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation protease"
                     /protein_id="HPC56159.1"
                     /translation="MLHPKTVVAGCGNPLFADDGFGPAVAEELQKTPLPPGVKVVDAG
                     ICGTYYIFSLVDAERTRRLIIIDSVDFGSEPGSIGFFGVDDLPAGSYCDPFSW"
     gene            complement(584..1012)
                     /locus_tag="PK679_09175"
     CDS             complement(584..1012)
                     /locus_tag="PK679_09175"
                     /inference="COORDINATES: protein motif:HMM:NF024087.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HPC56160.1"
                     /translation="MDQIPKPPCGLLCEICSLYRAGTDEALRVRVAQDFRIPREKASC
                     PGCRVTEGFCPVIDGQCATFRCAGEGGVAFCSECVNFPCRKLMPCADRASELPQNIKV
                     FSLSLRKNRGDEEWRKEILHVYRLYFKGKMVIGNGPVPGE"
     gene            complement(1204..2910)
                     /gene="mcrA"
                     /locus_tag="PK679_09180"
     CDS             complement(1204..2910)
                     /gene="mcrA"
                     /locus_tag="PK679_09180"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014867419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     alpha"
                     /protein_id="HPC56161.1"
                     /translation="MSKIEKVQKLFLKSLKEKFRGEDVASEHTTFYNFGGVRQSPRKR
                     EFIELSKVIEVQRGIPMYDPERCHLGGIPMGQRRLMTYEVSTTGVFVEGDDLHFVNNA
                     AMQQFWDDIRRTVIVGMDLAHQTLQKRLGKEVTPETINEYLHILNHAIPGAAVVQEHM
                     VETHPGLVDDCYVKVFTGDDDMADDIEPAFLIDINKLFPGKQAQTLKAEIGKSMYQAI
                     HVPTIVVRTCDGGTTSRWSAMQIGMAFIAAYRTCAGEAAVADLSFAAKHAGVIQMASH
                     LPARRARGPNEPGGIKFGLFGDIIQANRKYPNDPARASLEVVASGAVLFDQIWLGSYM
                     SGGVGFTQYATAAYTDNILDDFTYYGLNYVKDRYGYDYSAPSPDVTIRPTQDIVNDIA
                     TEVSLYAMEQYEQFPTMMEDHFGGSQRAAVIAAACGLSTSIPTGNSNAGLNAWYLSMI
                     IHKDAWSRLGFFGYDLQDQCGSANSLSMEPDRGAMGELRGPNYPNYAMNVGHQGEYAA
                     IVAGAHYGRNDAFCFDPRVKVAFADPSLKFNFAEPRKEFARGAIREFPVAGERSLIIP
                     AR"
     gene            complement(2914..>3032)
                     /gene="mcrG"
                     /locus_tag="PK679_09185"
     CDS             complement(2914..>3032)
                     /gene="mcrG"
                     /locus_tag="PK679_09185"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050524 - coenzyme-B
                     sulfoethylthiotransferase activity [Evidence IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     gamma"
                     /protein_id="HPC56162.1"
                     /translation="TIFHSLVGTPLRNDPEYIEYLQRIHSLRTKYGFMPMEG"
BASE COUNT          657 a          837 c          803 g          735 t
ORIGIN      
        1 cccacgagaa ggggtcacag taagagcccg cgggcaggtc atcgaccccg aaaaatccaa
       61 tggacccggg ttcagatcca aaatcgacgg aatcgataat tataagtctc ctcgtcctct
      121 cggcatcaac cagtgaaaag atgtagtatg tcccgcatat ccctgcatcc actactttca
      181 caccaggagg aaggggggtc ttctgcagtt cttcagcgac tgccgggcca aacccgtcat
      241 ccgcaaaaag ggggtttccg caccctgcaa cgactgtctt gggatgcagc attttttccc
      301 gttctccttt tcctctggaa cgcatacggg accttggagt cataagcccc ccggaaaaaa
      361 ccggaggtgg gattttggaa tggaattcac tccgtgcatt ccaggctcca tggtcgattg
      421 catgatgatt tcatggacat gtttgaagac cacgtccgcg gttcccattt tcatacgcgt
      481 atcccggaaa gaatgttttt cccctttgac ctcccgtcac gctgggaatc atggcgcagc
      541 aggaacctcc attcgcacaa atcccctgac gaggattgac ccttcattcc cctgggacgg
      601 gcccgttacc gatgaccatt tttcctttga agtagagccg gtaaacatgc aggatttctt
      661 ttctccattc ctcgtctccc ctgtttttcc tcagggaaag gctgaaaact ttgatattct
      721 ggggaagctc ggatgcacga tctgcacagg gcatcagttt ccggcaggga aaattaacgc
      781 attccgaaca gaatgcaact cccccctctc ctgcacaccg gaaagtcgca cactgcccgt
      841 caataacggg acagaaaccc tcggttaccc ggcacccggg acaggaagct ttctccctgg
      901 ggatacggaa gtcctgtgct acccggaccc ggagggcttc atcggttcct gcccggtaga
      961 gagaacagat ttcgcagagg aggccacagg ggggtttcgg tatctgatcc atggcaggtt
     1021 gattaattat taatataaaa aaatattact aaatcatatc attattataa tttgtatgaa
     1081 aaatactttt acatcatgca acggttctca cctgccccat ggatgagttt tcctccaggg
     1141 aaagagaaat ttgaatgatc ctctatttcc cttcccctgt cagttcgcat gacctttcca
     1201 ccttcaccgg gcagggatga tcagggagcg ctcacctgca acagggaact cccggattgc
     1261 cccgcgtgca aactcctttc gtggctcggc aaagttgaat ttcagggaag ggtccgcgaa
     1321 tgcgactttc accctcggat cgaaacagaa cgcgtcgttt ctcccataat gtgctccggc
     1381 cacgattgca gcatattccc cctggtgccc gacattcatc gcgtagttgg gatagttcgg
     1441 gcctctcagt tcccccatcg cacccctgtc gggttccatg gagagagagt ttgccgaacc
     1501 gcactggtcc tggaggtcat acccgaaaaa gccaaggcgg gaccacgcgt ccttgtggat
     1561 gatcatggag agataccatg cgttcaggcc ggcattggag ttcccggttg gaatcgacgt
     1621 cgaaagaccg catgcagctg caatgacagc agccctctgc gaacccccga agtggtcttc
     1681 catcattgtc gggaactgtt cgtactgttc catcgcgtaa agggagacct ctgttgcaat
     1741 atcgttgaca atatcctgtg tcggcctgat ggtcacatcg ggcgagggag ctgaataatc
     1801 gtagccgtac cggtccttca cgtagttcag gccgtagtac gtgaaatcgt cgaggatatt
     1861 atcggtatag gccgcagttg catactgggt gaacccgaca cctcccgaca tgtacgaacc
     1921 gagccatatc tggtcgaaga ggacagcccc tgaagccacg acttcgagtg acgcacgtgc
     1981 gggatcgttg ggatacttgc ggtttgcctg gatgatgtcc ccgaaaaggc cgaacttgat
     2041 tccgccgggt tcgtttggcc ccctcgcccg ccgggcaggc aggtgagacg ccatctggat
     2101 gactccggcg tgttttgcgg caaacgagag gtctgcaact gcagcctccc cggcacatgt
     2161 cctgtaagca gcaatgaatg ccatacctat ctgcattgct gaccagcggc tggtcgtccc
     2221 gccgtcacag gtccgcacga cgattgtcgg gacgtggatg gcctggtaca tcgacttccc
     2281 gatttcggcc ttgagtgttt gggcctgttt cccgggaaag agtttgttga tgtcgatgag
     2341 gaatgcaggc tcgatatcgt ctgccatgtc gtcgtccccg gtaaatacct tgacgtaaca
     2401 gtcatccacg agtcccgggt gcgtctcgac catgtgttcc tggacaacag cagcgcccgg
     2461 tatggcgtgg ttcaggatgt ggaggtactc gttgatggtc tcgggtgtga cctcttttcc
     2521 cagccgtttc tggagcgtct ggtgggcaag gtccatcccg acgatgactg tccgcctgat
     2581 atcgtcccag aactgctgca ttgctgcatt gttgacgaaa tggaggtcgt ctccctccac
     2641 gaagacaccg gtcgtggata cctcgtaggt catgagcctg cgctggccca tgggtattcc
     2701 cccgaggtga cagcgttcgg ggtcgtacat cggtatcccc cgctggacct cgatgacctt
     2761 tgacaattca ataaactcgc gtttccgggg tgactgccga acgccaccga agttgtaaaa
     2821 tgtcgtgtgc tcggatgcca cgtcctctcc acggaacttt tccttgaggg atttcagaaa
     2881 gagtttctgt actttctcga ttttggacat tgtttacccc tccatgggca tgaagccgta
     2941 ttttgtcctt aaagagtgga ttctctggag gtactcgata tattcggggt cgttcctgag
     3001 gggggtcccg acgagagaat ggaatatcgt cg
//
LOCUS       DAOOJU010000070         3018 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_25168_length_3018_cov_9.794128, whole genome shotgun sequence.
ACCESSION   DAOOJU010000070 DAOOJU010000000
VERSION     DAOOJU010000070.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 3018)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3018)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3018
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_25168_length_3018_cov_9.794128"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..638)
                     /locus_tag="PK679_09190"
     CDS             complement(<1..638)
                     /locus_tag="PK679_09190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56163.1"
                     /translation="MEHLIPSTLCPAMLLIMALSVCPSPAAVPVASTPDAIHISSITT
                     VACEGTVDHGNTLSWQQSGTSLHDPPLDAGGIYSVWFDEEGNPVYGWTADPALADLLD
                     TPVPPGEVRYTAGYSATLLAGQGITELEKNMKINSGEENSGNVDTSTLISFNPSNGHG
                     DVAFSEDLAIDAAAAHTTRENSLSCTFLPDDCPFIPPFCEVVEMGSSSDISRG"
     gene            complement(692..2686)
                     /locus_tag="PK679_09195"
     CDS             complement(692..2686)
                     /locus_tag="PK679_09195"
                     /inference="COORDINATES: protein motif:HMM:NF040138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kelch repeat-containing protein"
                     /protein_id="HPC56164.1"
                     /translation="MVGISSGDHLVSSFSGRPTSGHAPLTVTFTDVSSGDPTGWAWYF
                     GDENYTGSEWKELSGNAPWGTRYGHAAVAMPDGSIVLTGGGPGYKNDVWVSLDGGTTW
                     NVQNESSGWPGREFHSAVVLPDGSIVLMGGYNGTYLRDVWRSVDKGVTWTLQAAGAPW
                     AARAKHSSVALPDGSILLMGGFDGTSPKNDVWRSTDKGRTWTQQTSRAGWSARYGLAG
                     VVLPDGCIAVIGGRTSSGYSREMWLSPDQGMTWTNPPLGNLISLYPRGYHSAVALPDG
                     SILVAGGENTGKTVKDMVRIARKTGAWSVERYEIPLAVGRYCHAGVILPDGGLVLMGG
                     TNDTAMKSDVWHFETASPIRDPIHEYREEGTYSVTLQVSGSGGYNTSTRQDFITVYPP
                     LSPPAVTGIEPDTGENGTAFIVVNLSGTNFDTMNIPSVKLTRAGLPDILAENVSVHSP
                     SQLTCTISPFGHEAGQRDVIVTNPDGKSGVLPGGFTLTQQPPVADFTARPQSGTAPLA
                     VEFSDTSTGVPSSWTWDFGDGTSGSGKNPLHTYTLPGTYTVTLTVRNGGGSSTITHPD
                     CISVTAVRPPIIGVFSPASMMHGKTVNVAIIGNNFQKGATVRLDQGTATIPVTVTAII
                     PPSKITGVVSVPASARGRWSLAIRNPDGGECVRANAIIIT"
BASE COUNT          649 a          836 c          858 g          675 t
ORIGIN      
        1 ccccgtgaaa tgtccgagct gctgcccatc tccacgacct cgcagaacgg cgggatgaac
       61 gggcagtcat ccggtaaaaa tgtgcaggaa agggaattct ccctcgtggt gtgtgccgct
      121 gcagcatcaa tcgcaaggtc ttcggaaaat gcaacatcac cgtgcccatt cgacggatta
      181 aaagatatga gggtactcgt atccacgttg ccgctattct cctcgccgga attgattttc
      241 atgttctttt ccagttccgt tattccctgc ccggcaagga gggttgcaga gtatcctgca
      301 gtgtatcgca cttcaccggg tggcacaggc gtgtcgagga gatcggccag ggcagggtcg
      361 gccgtccatc catatacggg attgccctcc tcgtcaaacc agactgaata gataccccct
      421 gcatcgaggg gcgggtcatg gagggatgtg cccgattgct gccaggaaag cgtgtttcca
      481 tggtcgactg tcccttcaca ggcaacagtt gtgatactcg agatatggat cgcatccggg
      541 gtggaagcaa ccgggactgc agcaggggaa gggcagacag acagggccat gatgaggagc
      601 atggcggggc agagagtcga tggtatgaga tgttccacgc gatttttcct gaatgttttt
      661 ttcataatga gggtcatcat ccaccgtcct ttcaggtaat gatgatcgca ttggcccgta
      721 cgcattcgcc cccgtccggg ttccggatag caagtgacca tctgcccctc gcggaggcag
      781 gaaccgaaac aactcctgtg atcttcgagg gcggtataat ggctgttaca gtcaccggga
      841 tagtggcagt gccctggtcc agcctgacgg tcgcaccctt ctggaagttg ttgccgataa
      901 tcgcgacgtt cacggtcttt ccgtgcatca tcgatgcagg gctgaacacc ccgataatcg
      961 ggggacggac agccgtgaca ctgatacaat ccgggtgggt gatggtactg ctccctccgc
     1021 cgttgcgcac ggtcagggtc acggtatagg tccccggcaa agtataggta tgcaagggat
     1081 tcttcccgga gcccgaggtg ccgtctccaa agtcccaggt ccatgatgag ggaacgcccg
     1141 tggacgtgtc ggaaaattca accgcgaggg gagcagttcc cgattgtggc cgggccgtga
     1201 aatcggccac cggcggttgc tgggtgaggg taaacccacc tggcaagacc cctgattttc
     1261 catcggggtt ggtgacaata acatcccgtt gccctgcctc gtgcccgaat ggggaaattg
     1321 tgcaggtcag ttgagagggg gagtgcaccg atacattttc cgcgaggata tcggggagcc
     1381 ccgcacgtgt cagtttcacg gacggtatat tcatggtgtc aaaattcgtc cctgacaggt
     1441 tcacgacaat aaatgctgtg ccgttctctc cggtgtccgg ctcgattcct gttaccgccg
     1501 gtggtgacag cgggggatag acagtgatga agtcctgcct cgtggacgta ttatacccgc
     1561 cgcttcccga tacctggagt gtcaccgaat atgtcccttc ttcccggtat tcatggatcg
     1621 gatcccggat tggtgatgca gtttcgaaat gccagacgtc acttttcatg gcggtatcat
     1681 tagtccctcc catgagcaca aggcctccat ccgggaggat gacgccggca tggcaatacc
     1741 tgccgacggc gagggggatc tcgtatcttt caacagacca ggcccccgtc ttccgggcga
     1801 tgcggaccat atccttcacc gtctttccgg tgttctcccc accggcaacg agaatgcttc
     1861 cgtccggcag tgcaaccgca ctatggtagc cgcggggata caacgaaatg aggtttccga
     1921 ggggagggtt ggtccaggtc atcccctggt caggggaaag ccacatttcc ctggagtaac
     1981 cggatgatgt cctgcccccg ataacggcaa tgcagccatc gggaaggaca acgccggcca
     2041 ggccgtaccg ggcgctccac ccggccctgg acgtctgctg tgtccatgtc cgccccttgt
     2101 ccgtggacct ccagacatcg tttttcgggc tggtgccatc gaacccaccc atgagcagga
     2161 tgctcccgtc cgggagggca acagaggaat gcttggcccg ggctgcccag ggagcaccgg
     2221 cagcctgcag tgtccacgtc acacccttgt ccaccgaacg ccacacatca cgtaaataag
     2281 tcccgttata cccgcccatg agaacgatac tcccgtcggg cagaacgaca gcggaatgaa
     2341 attcccggcc cggccagcct gaactttcgt tctgcacgtt ccatgtcgtt ccaccgtcta
     2401 atgataccca gacatcattt ttataccctg gtcccccgcc tgtgaggaca atgctcccgt
     2461 ccggcattgc caccgcggca tgcccgtacc tcgtacccca tggagcgttt ccggacagtt
     2521 ctttccactc cgatcccgta taattctcgt cgccgaagta ccaggcccag ccggtggggt
     2581 ctccggacga gacgtcagta aatgtgactg tcagtggtgc atgtccgctg gttggtcttc
     2641 cggagaaaga tgaaacgagg tggtctccgg atgatatccc taccataagt acgaggcaga
     2701 gaaacaggat aatctggttc tgtaaacatg acatcgtgat acaatctcct gcaatgatgg
     2761 ggaaagaccc ccagatgcca gaatggaggc aaggacacat cacatgtcct ttacagtgat
     2821 ggtgcggatc actccccatc aggttgagta accggttgtg gaggttgcac cgatggaaag
     2881 gaataatgtg ccattgaatg gtctaaaagt cttcttttgg accaatctat tctgcatttg
     2941 gcttattagg gtctttacag cggttttatg gtgaaaaaag aagtttatac ttgggaaata
     3001 agaagatttc ttttgtga
//
LOCUS       DAOOJU010000071         2809 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_27709_length_2809_cov_7.015614, whole genome shotgun sequence.
ACCESSION   DAOOJU010000071 DAOOJU010000000
VERSION     DAOOJU010000071.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2809)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2809)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2809
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27709_length_2809_cov_7.015614"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(1..180)
                     /locus_tag="PK679_09200"
     CDS             complement(1..180)
                     /locus_tag="PK679_09200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56165.1"
                     /translation="MAGTARLSMSGKAVNFQIGDYFYTVPVARVLDVLDGRARKTAVF
                     VERDVIEKVHGTIIN"
     gene            complement(365..>2809)
                     /locus_tag="PK679_09205"
     CDS             complement(365..>2809)
                     /locus_tag="PK679_09205"
                     /inference="COORDINATES: protein motif:HMM:NF019911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEGA domain-containing protein"
                     /protein_id="HPC56166.1"
                     /translation="FLPAGAVLPSYSFRGTVTDVSRSDNTVTILVTHKWGCVYDGRET
                     PCSWMTMTPKVLTGTVPVPEVFDKVRVGSSVEAGSIGSQGVKWAGIGVLAPSTASEPL
                     HATDLYGDPGMLPAPLAAGYAVSAENQPDCACCSGSVCEAASANVTISKNDLLVWNGT
                     LGAGGEGYYEDPADGTSVSVTFISGQAPASLCPDTPFGMSGVQPVSVFIVHVSRNGPG
                     PGPTVTPAQSGMLSVSSIPPGAAILLDGVAKGSTPKTISGILPGVHTLSLAKEGYAPY
                     ERNITISAGKPVVVTAKLTPLYGSLRIQSAPQGASVLLNGTDAGVTPLVITNLVPGTY
                     TVSLSKTGYQASNQTATVVAGQEKVLFVTLTKKGDGSEKIEAFIAALEQEGFTVQQGK
                     FEMFDVLAMYDAHVIPSCYGNNPSTPYLTYKLPGYPGLKEGGRVSDAPINPANKGLWL
                     DYFMEPDEAIVFVGSTPPEVKYFSYRSYIGTRWFTQLDDYQRIFASLGDTLNNYRIKT
                     GMAPGRPGPYKKPIMIITTADKGTNERVRSAAQKAGYPAGMINDDIIPSGLIRMGLSN
                     TSDTIAFIHRLAFFANETEGAEYMNGTPGYVFRLTPTTSRTPQPYSVPRLIPRGTGDA
                     HELDLLTTQESLRDAIVARYGSGRVATANHTEIWVLEGYDSLQREADALGDNRDALYL
                     RNGDYLLSDDDFIIVYGVNHKATGKGIYTNIAVYGIQALNGVVAVTDADIAGSATSYL
                     PGNPNADLFYVWKFARHCNGEAGCTEVPSCCGGLGIPEDVPVRIAYRTYVEPGTGIGP
                     AAPEILYDQAIHFAPA"
BASE COUNT          520 a          823 c          873 g          593 t
ORIGIN      
        1 ttaattgata atagtgccat gtaccttctc aattacatcc ctttccacga agactgccgt
       61 tttcctcgct cgtccatcca gcacatcgag gactcttgcc accggcacgg tgtagaaata
      121 atcaccgatc tggaaattga cagccttccc tgacatcgag agccgggccg ttcctgccat
      181 cttgtcgccc gcgaggaagc ggacttcaca ggatttgcca tccagctatt ttcccagtca
      241 tgcaccagca agaatacccg cccgttctcc ggtttcgaag gacacaccca aaggacgatg
      301 acgcatcatc cgggaccccc cgccccttcc gcacgactcg aaaaataggt gatgtgagag
      361 tatttcacgc cggggcgaag tgaatcgcct ggtcgtagag gatctcgggg gcggccgggc
      421 cgatccctgt ccccggctcg acataggtcc ggtacgcgat gcggacaggc acgtcctccg
      481 ggatcccgag gccaccgcag caggacggga cctcggtaca acccgcctcg ccattgcagt
      541 ggcgggcaaa cttccacacg tagaagaggt ctgcattggg gtttcccggc aggtaactgg
      601 tggccgaacc ggcgatatcg gcatcggtga cagcgacgac accgttcaat gcctggattc
      661 cataaaccgc gatgttggtg tagatccctt ttccggtcgc cttgtggttg acaccgtaca
      721 cgatgatgaa atcgtcatct gagaggaggt aatcgccgtt tctcaggtag agtgcgtccc
      781 ggttgtcccc cagggcatcg gcttcccgct ggagcgagtc atatccttca agtacccaga
      841 tttcagtatg gttcgcggtt gcaaccctcc cgctcccgta ccgggcgaca atcgcatccc
      901 ggagcgattc ctgggtcgtc aggaggtcga gttcatgggc atcgcctgtt ccgcgtggaa
      961 tgagccgcgg cacgctgtag ggttgcggtg tgcgggaagt ggtgggcgtc agcctgaaga
     1021 cgtaaccggg agtgccgttc atgtattccg ccccctctgt ctcgttggca aagaaggcca
     1081 ggcggtggat gaacgcgatg gtatccgacg tgttcgagag ccccatccgg atgagcccgg
     1141 acgggatgat gtcgtcgttg atcatgcccg ccgggtaccc tgctttttgc gcagcactcc
     1201 tcacccgttc gttcgtcccc ttgtcggcag tggtgatgat catgatgggt tttttgtacg
     1261 ggcccggccg tcccggagcc atgccggtct ttatgcggta attgttgagg gtatcgccca
     1321 ggcttgcgaa gatccgctgg tagtcatcca gttgggtaaa ccagcgtgtt ccgatgtaac
     1381 tgcggtaact gaagtatttc acttcgggag gagtcgatcc cacgaagacg atcgcctcgt
     1441 ccggttccat gaagtaatcc agccagaggc ccttgtttgc ggggttgatg ggtgcatccg
     1501 agaccctgcc accctccttg agacccgggt aaccggggag cttgtaggtg aggtaggggg
     1561 tgctcgggtt gttcccgtaa cagctgggga tgacgtgtgc gtcatacatg gcgagcacat
     1621 cgaacatctc gaattttccc tgctggacgg tgaagccttc ctgctccagt gccgcgataa
     1681 aggcctcgat cttctccgat ccgtctcctt tcttcgtcag tgtcacgaag aggacctttt
     1741 cctgcccggc aaccaccgtg gctgtctggt tggaggcctg gtagcccgtc ttcgagaggc
     1801 ttaccgtgta cgtccccggc acgaggttcg tgatgacgag cggggtgacc cctgcatccg
     1861 ttccgttgag gagaaccgat gctccctgcg gggctgactg gatccggagg ctcccgtaga
     1921 ggggagtgag cttcgcggtg acgacaaccg gttttccggc agaaatggtg atgttcctct
     1981 cgtagggggc gtatccttcc tttgcaaggg agagggtatg gacaccgggt aaaataccgg
     2041 agatggtctt cggggtcgaa ccctttgcga ccccgtcaag gaggatggct gctcccggcg
     2101 ggatagagga gacgctgagc atgcctgact gtgccggtgt cactgtcggg ccgggtccgg
     2161 gtccgttccg gctgacatgg acgatgaaga cagataccgg ctggacccct gacatgccga
     2221 atggcgtgtc ggggcagagg gatgccggtg cctgcccgga gataaacgtg acagagacag
     2281 acgtcccgtc agccgggtct tcgtagtatc cctccccgcc tgcaccaagc gtcccgttcc
     2341 acaccagaag atcgtttttg gagatggtga cgtttgcaga cgctgcctcg cagaccgaac
     2401 cggagcagca tgcgcagtcc ggctggttct cggctgatac cgcgtagcct gctgcgaggg
     2461 gtgcagggag catgcccggg tcaccgtaca ggtcggtcgc gtggagaggc tcggacgcgg
     2521 tcgacggtgc caggacccct atgcctgccc atttcacgcc ctgcgaaccg atgctcccgg
     2581 cctcgacgga cgagccgacc ctgaccttgt caaagacctc cgggacagga acggtgccgg
     2641 tgagcacctt cggggtcatc gtcatccagg agcacggggt ctccctcccg tcatacacgc
     2701 agccccactt gtgggtcacg agaatggtga cggtgttgtc ggacctcgat acatcggtca
     2761 cggtcccacg gaagctgtag gacgggagga cggctcccgc cgggaggaa
//
LOCUS       DAOOJU010000072         2799 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_27842_length_2799_cov_12.073615, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000072 DAOOJU010000000
VERSION     DAOOJU010000072.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2799)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2799)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2799
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_27842_length_2799_cov_12.073615"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..2576)
                     /locus_tag="PK679_09210"
     CDS             complement(<1..2576)
                     /locus_tag="PK679_09210"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56167.1"
                     /translation="MAIRKDGSTFPVTIYSAPIVSGAEVTGIRGIITDNTAQKAFENA
                     IRESERLYRTIFETTGTATVLIENDGTISLANSEFVRLSGFPREEIENRKTWMDFVVR
                     EDLDRMVAQHRLRRSDPEKALKNYEFRFVTAKGEIRHIYLSVNLIPGTQKSVASLLDI
                     TPRKKAEEALIETNKDYNALLDQIQDVYYRSDTEGRLVKASRSWAVLLGYDDVAECIG
                     RPIAEDFYDNPADREKLLEEIYRNGRVTNYEVTLRKKDGTPVIVSTNSYLVHGPDGTV
                     LGVEGTFRDITGQIRARDELRRSEERYRRILDTVPSAIVVYEAVDDGEDFIIRDFNPE
                     AERIERMPAGDVIGKRVTEAFPGVREFGLLPVFQRVWKTGQAAYFPPALYRDQRDPGT
                     WRENWVYRLTSGEIVAIYRDVTRWVRAQEDIKKSEERYHHIIESQTEFICRFLPDGTH
                     VFVNRAYADYFGTTPEELAGRVFRPAIHPDDRGRVREFFASLTPDHPVGTIEHRIIMP
                     DGEVRWQQWSDRAIFDEDGRLVEYQSVGRDVTGQKRAMEELERYRQRLEAAMDLAHMA
                     DWEFDIASGILTFNDRFYALYGTTAEREGGYQMPAGVYAREFVHPDDVYMVAEEMEKA
                     RKANSSDFFSIRQHRIIRRDGQVRWIVVRIGLIRDESGRPIKTHGVNQDITELKRAEE
                     ALREREERFQRLAENAEDLVYRYELFPARRYTYVSPSATKISGYTPEEHYADPDLGFK
                     MALEEDRPLLEALARGDDPAAIKRPLELRMRRKDGSVFWTEMVNVPILDAQGRVVAVE
                     GIGRDITDRKRAEEALRTANRKLSLLSSLTRHDIANQLTVIRGYATLLAEEQPGPGVL
                     EKT"
     gene            2563..>2799
                     /locus_tag="PK679_09215"
     CDS             2563..>2799
                     /locus_tag="PK679_09215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56168.1"
                     /translation="MRIAMYSPGGKSAGYPARKYPLYTLFCPLPVFGSDHPESRESPV
                     EVLFSVAEQFEGLPVCIGQRRLPVHLEDDLGCHVC"
BASE COUNT          452 a          877 c          823 g          647 t
ORIGIN      
        1 gttttttcaa gcacgccggg tccgggctgc tcctccgcaa gaagggtcgc atagccccgg
       61 atgacggtga gctggttggc gatatcgtgg cgggtgaggg acgagaggag gctgagcttg
      121 cggttcgccg tgcggagtgc ctcctcggcc cgtttccggt cggtaatgtc gcggccgatc
      181 ccttcgacgg caacgactct cccctgtgca tccaggatgg ggacgttcac catttctgtc
      241 cagaaaacgg acccgtcttt tctccgcatc cgcagttcga ggggtctttt gatggcagcg
      301 gggtcatccc cccgggcgag agcctccaac agggggcggt cttcttcgag cgccattttg
      361 aatcccaggt ccgggtccgc gtaatgctct tcgggagtgt accccgagat tttcgtggcc
      421 gagggagaga catacgtata cctgcgggcg gggaagagct cgtagcggta gaccaggtcc
      481 tctgcgttct ccgcaagccg ttggaacctc tcctccctct cccggagggc ttcctcggcc
      541 ctttttagtt ctgtgatgtc ctggttgacg ccatgggtct tgatcggccg gcctgactcg
      601 tccctgatga ggccgatgcg cacgacgatc caccgcacct gtccgtcccg gcggatgatc
      661 cggtgctggc ggattgagaa aaagtccgaa ctatttgcct tccgggcctt ctccatttct
      721 tcggccacca tgtacacgtc gtccgggtgg acgaactcac gggcatagac cccggccggc
      781 atctggtacc ctccctcccg ttccgcggtc gtgccgtaca gcgcatagaa ccggtcattg
      841 aaggtgagta tccctgatgc aatgtcgaat tcccagtcgg ccatgtgggc aaggtccatt
      901 gccgcttcga gcctttgcct gtacctttcg agttcctcca tcgcccgttt ctgcccggtg
      961 acgtcacggc cgaccgactg gtactcgaca agcctcccgt cttcgtcaaa gattgcccgg
     1021 tcgctccact gctgccaccg gacctccccg tccggcatga tgatccggtg ctcgatggta
     1081 ccaaccgggt gatcgggggt gagcgatgcg aagaactccc gcaccctccc gcggtcgtcc
     1141 gggtggatgg cgggccggaa cacgcggccg gccagctcct ccggggtcgt gccgaaatag
     1201 tcagcgtacg ccctgttcac gaagacatgg gtcccgtcgg gaaggaaccg gcagatgaac
     1261 tcggtctggg actcgatgat gtgatggtag cgctcctcgc tctttttgat gtcctcctgt
     1321 gcccggaccc agcgggtgac gtccctgtag atggccacga tctccccgct cgtcagcctg
     1381 tagacccagt tttcccgcca tgtaccggga tcgcgttggt ccctgtagag tgccggcggg
     1441 aagtatgcgg cttgccccgt cttccagacc cgctggaaca ccgggaggag cccgaattcc
     1501 cggacacccg ggaaggcttc ggtgacacgc ttcccgatga cgtctcctgc cggcatgcgc
     1561 tcgatccttt ctgcttccgg gttgaagtca cggatgatga aatcctcgcc gtcgtcgacg
     1621 gcttcgtaca cgacaatggc actcggcacg gtgtcaagta tccggcgata gcgctcttcg
     1681 ctcctgcgca gctcgtcccg ggcccgtatc tgcccggtga tgtcgcggaa cgtcccctcc
     1741 acgccaagga ctgtcccgtc cggtccatgg acgaggtagc tgttcgtcga gacaataacg
     1801 ggggtcccgt cctttttccg gagggtcact tcgtaattgg tcaccctccc gttccggtag
     1861 atctcctcca gcaacttctc cctgtctgcc gggttatcgt aaaagtcctc tgcaatcggt
     1921 ctcccgatgc actccgcaac atcatcgtac ccgagcagca cggcccatga acggctcgcc
     1981 ttcacgagcc ttccttccgt gtcactccgg tagtagacgt cctgtatctg gtcgaggagg
     2041 gcgttataat ctttgtttgt ttcgatgagg gcttcttctg ccttcttgcg gggcgtgatg
     2101 tccagcaggg acgcaacgct cttttgggtg cccgggatga ggttgaccga gaggtaaatg
     2161 tgccggatct ctcctttcgc cgttacaaac cggaattcat agtttttgag ggctttttcc
     2221 gggtctgatc gcctgagacg gtgctgggca accatccggt cgaggtcttc cctgaccacg
     2281 aagtccatcc acgtcttcct gttctcgatc tcttcccggg gaaaaccgct caaccggacg
     2341 aactcggaat ttgcaaggga gatcgttcca tcgttctcga tgaggacagt tgccgtcccg
     2401 gtcgtctcga agatcgtccg gtataacctc tcgctctccc ggatggcatt ctcgaaagcc
     2461 ttctgggccg tgttatcggt gatgatcccg cggatcccgg tcacttctgc cccggaaacg
     2521 atcggcgctg agtatattgt gacggggaag gtgctgccgt ccttgcggat tgccatgtac
     2581 tcgccggggg ggaagagtgc ggggtacccc gcccgcaaat accctctgta tactctcttt
     2641 tgcccgctcc ctgtcttcgg gagcgatcat ccggagagca gagagtcccc ggtcgaagtc
     2701 ctcttcagtg tagccgaaca gttcgaaggc cttccggttt gcataggtca gcgtcgtctc
     2761 ccggtccatc tcgaagatga cctggggtgc catgtctgc
//
LOCUS       DAOOJU010000073         2679 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_29657_length_2679_cov_9.043064, whole genome shotgun sequence.
ACCESSION   DAOOJU010000073 DAOOJU010000000
VERSION     DAOOJU010000073.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2679)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2679)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2679
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_29657_length_2679_cov_9.043064"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            282..2321
                     /locus_tag="PK679_09220"
     CDS             282..2321
                     /locus_tag="PK679_09220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004077270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HPC56169.1"
                     /translation="MTAPPQSGAQKILLFLVLLIALVLPVAADGTPGLVPSDILAMET
                     PGHFTLSYDGANLLYIRSTGTDLAPPQNNGTLMYIDVRAATERPLSGPAESVTAYALA
                     PDGNTVVYAAMPRAGGPVSMYRIHVRDSRAYRLDNTTDELAGDFAFLGNDRLIFTGAP
                     AGADPGSSDVIVADEPPAPVILKTYSLGDHTITPLTANNDVITIWAPSPDGRYVLYKA
                     APDPESWQAGATFRYVLLDTQNGQERELFTSVEGYQDTNQFAWSPDSTVVYIERFVNG
                     GLRYPVQDASYLQAYTPATRTLEEIPLGWDRGLFIDLFNEDIEVNPFNGGAYLLLADG
                     TNPRLARAVKTSTGWQVSLMDGRDQGNIYAIESDRTGSTIVYNRNSASSPPQLFRAGM
                     DGNSITNPVQLTRLNPDLVAQDLGTSEVTSWNGARGETVSGVVRYPPGYVQGNQYPLV
                     LVIHGGPNYADFDSWRDTWEFPYHLITDKGAVTLSVNYHGSTNFGLDFARSIENAHYY
                     DLPVEDLRTGIEHLVARGIVNRSQIGVTGWSNGGILSLALVVNDPTIRAAVSGAGSAD
                     DFSQVANTNGIVMNKMYYNKSPYEDPQAYLAILPVFQAEKRRTPLLMMIGTDDIQVDP
                     AGAWVTYRAYKEGSPAPIRFLLFQNQPHHMTTMETQNRKVQEELAWLDRYLLSAA"
     gene            2394..2612
                     /locus_tag="PK679_09225"
     CDS             2394..2612
                     /locus_tag="PK679_09225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56170.1"
                     /translation="MSEGQQSDALRRLVVFVIVPAILGTILALARYYAVELPAQAALL
                     HTPRSCYPCPCGFPTRCVGGCCRPPGAV"
BASE COUNT          551 a          819 c          795 g          514 t
ORIGIN      
        1 aggattatgg cagcaatgat gatggcatgg gtcgggagcg tcatgtccgg gcacggggat
       61 tgttcttcag tatttttcgc gtctgacatc ccttggctgg ttcctgctaa atacattgcg
      121 cgggcctgac cggtgcaggg agtgaggatg gcagcagggg tgcctgggta tcgggatgcg
      181 gggattgggc ggctccaacc ttcggacctg caccagcccg taaaagaggc gacactttat
      241 taccaatccg gaccttttga ggagtcatag gagattgtgc catgacagcc ccacctcaat
      301 ccggtgcgca aaaaatcctg ttattcctgg tcctgctgat cgccctcgtc ctcccggtgg
      361 cggcagacgg cacccccggc cttgtgcctt cagatatcct ggcaatggag acccccggcc
      421 atttcaccct ctcgtatgac ggggcaaacc tcctgtatat ccggtccacg ggaacggatc
      481 tggctccccc gcaaaacaac ggcaccctga tgtatatcga tgtccgggca gcaaccgaac
      541 gacctctttc gggtcccgca gaatcggtca cggcctatgc ccttgcaccg gatgggaaca
      601 cggtcgtgta cgcggcaatg ccccgggccg gcggccccgt ctcgatgtac cgtatccatg
      661 tccgcgactc ccgggcatac cggctggaca ataccacgga cgaacttgcc ggagattttg
      721 ccttcctcgg gaatgaccgg ctcatcttta ccggggcacc ggccggtgcg gatccgggca
      781 gcagcgatgt catcgtcgcg gatgaaccac cggccccggt catcctgaag acctactcgc
      841 ttggggacca cacgataacc ccgctcactg caaacaatga cgtgatcacc atctgggcac
      901 cctcgccgga cgggaggtat gtcctgtaca aagcggctcc cgaccccgag tcgtggcagg
      961 ccggggccac gttccggtac gttctcctcg acacgcagaa tgggcaggag cgggaactct
     1021 tcacgtccgt tgaggggtac caggacacca accagttcgc atggtcgccg gacagcaccg
     1081 ttgtctacat cgagcggttc gtgaacgggg ggctgcggta cccggtccag gatgcctcgt
     1141 acctccaggc atataccccg gcaacccgca cgctggagga gatcccgctc gggtgggacc
     1201 ggggcctctt catcgatctt ttcaatgaag atatcgaggt gaacccgttc aatggcgggg
     1261 catacctcct ccttgctgac gggacgaacc cgagacttgc gagggcagta aaaaccagca
     1321 ccggctggca ggtctccctc atggacggca gggaccaggg gaacatctat gccatcgaga
     1381 gtgaccggac cggctcaacc attgtctaca accgcaactc agcatcctcc cctccgcagc
     1441 tgttccgggc aggtatggat gggaacagca tcacgaaccc ggtccagctc acccgcctca
     1501 acccggacct tgtggcacag gacctgggca catccgaggt cacttcgtgg aacggggccc
     1561 ggggggagac ggtctcgggc gttgtccggt acccgccggg atatgttcag gggaaccagt
     1621 acccgctcgt cctcgtcatc catggcggac cgaactatgc ggacttcgac agctggcgcg
     1681 acacctggga gttcccctac catctcatca cggacaaagg agcagtcacg ctctcggtca
     1741 actaccatgg cagcacgaac ttcggtcttg acttcgcccg gtccatcgag aacgctcatt
     1801 actatgacct gccggtcgaa gacctgagga ccgggatcga acatctcgtg gcccggggca
     1861 tcgtcaaccg ttcgcagatc ggcgtcaccg gctggtcgaa cggggggatc ctctcgcttg
     1921 cccttgtggt caatgacccc accatacggg cagcggtatc cggtgccgga agtgccgatg
     1981 acttctcgca ggtggccaac acgaatggca tcgtgatgaa caagatgtac tacaataaga
     2041 gcccgtacga ggacccgcag gcatatttgg ccatcttacc ggtgttccag gcagagaaac
     2101 ggagaacccc gctcctgatg atgatcggga ccgatgatat ccaggttgac ccggcgggtg
     2161 cgtgggttac ataccgggca tacaaggaag ggagcccggc cccgatccgg ttcctcctct
     2221 tccaaaacca gccgcaccac atgacaacga tggagacaca gaaccggaag gtgcaggagg
     2281 aactcgcctg gcttgaccgg tatctcctgt cggccgcatg agccgcatcc ttgtggagga
     2341 acaatatcct catatcagca tgggcacagt gaggattcac gggagacatt tccatgagtg
     2401 aaggacaaca atccgatgca ctgagaagac tggtggtatt cgtcatcgtt cctgcgattc
     2461 ttggtacaat cctcgcgctg gctcggtact atgctgttga acttccggca caggcagcac
     2521 tgctccacac gccccggagc tgttacccct gcccgtgcgg gttcccgaca aggtgtgtcg
     2581 ggggctgctg tcgtccaccc ggggcagtgt gagaggatgc cagcaaaaga tctcgtgtat
     2641 gtgaaggaaa agccgggcat ggggcttggg atattcgct
//
LOCUS       DAOOJU010000074         2656 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_30003_length_2656_cov_8.945406, whole genome shotgun sequence.
ACCESSION   DAOOJU010000074 DAOOJU010000000
VERSION     DAOOJU010000074.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2656)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2656)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2656
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_30003_length_2656_cov_8.945406"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..712)
                     /locus_tag="PK679_09230"
     CDS             complement(<1..712)
                     /locus_tag="PK679_09230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012106294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HPC56171.1"
                     /translation="MPGDERVNAGISELIGAILLVGLVITAMAIVAVVVLSNPPPEEI
                     PHLSALASNTSNTILLYHNGGDALKEEQTIISVNNVPEVPHSKITIRNEDGTSESATW
                     DITKTPWTVGKALVVTYEGPGMPEYVQLIYRGGSAEALLLTEYFVPVNIPPPGPICSD
                     VSASFTANITSGSAPLTVSFTDDSTSQDPITSWSWNFGDGSTSTSKNPTHTYTNPGTY
                     TVTLMAGNTCGNSATKSAS"
     gene            complement(814..1212)
                     /locus_tag="PK679_09235"
     CDS             complement(814..1212)
                     /locus_tag="PK679_09235"
                     /inference="COORDINATES: protein motif:HMM:NF019407.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin N-terminal domain-containing
                     protein"
                     /protein_id="HPC56172.1"
                     /translation="MREGNASDSAVSELIGVLLLIAVISLAISILGVTILSNINVSQV
                     PAVSFVIGYENSIITIIHAGGDVLPEGSYRIYVDGTDRTQEFVPIPDSTPFRPGTALE
                     LPAVSSPRTVMVVSRGNDGRETMLVQKYFP"
     gene            complement(1209..>2656)
                     /locus_tag="PK679_09240"
     CDS             complement(1209..>2656)
                     /locus_tag="PK679_09240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56173.1"
                     /translation="APLTDEGLSEVIGFILILGIIAAVASLYITYVVPAQGRELEIKH
                     MAQVNDQFLQYKTTIDSLWINGQENVPISNTFTLGTVTGLTQGAFVVPVFQPYPSSGM
                     IVVNERGEDITLNADVLVQGFPGNMQPNINPIYREPDHLYIQLKTTNRDEHGGVIIYP
                     DNPNPQWYIVLNITPIIVSTGTNSPAPSVLPPLEQPNVPDIASWINTILVPNWTLMVQ
                     GLGVSRPALTMTLVKNDNATFSNLTIIPEIINNRNYTIDLLDDAYGLAEALDYPLKIR
                     TPIFSTPNIQVFYPVQVGYNSAEIVFSHPMDSLEFRSSNNYWIQQDYYYQLGGVFLRQ
                     PDGMVSKVIPLISVTNKTGLPTVRMVDIFIDGSGNIGGSSPVQVVSTLTSLQENTIDQ
                     QKLATGIPNARNVTFIISAQDQQTAQMWNQTFSRIRQAALSEDFPPAWIPAPVQTGNT
                     VQFTVRDPDNYSLFLDYTRVNLSVNLQTVAL"
BASE COUNT          646 a          596 c          711 g          703 t
ORIGIN      
        1 tgctcgctga tttagtcgca ctgttcccgc aagtgttccc tgccatcagg gtgacagtat
       61 atgtgcccgg atttgtgtag gtgtgggttg ggttcttcga ggtggaggtt gatccgtcac
      121 cgaagttcca tgaccacgag gtgataggat cctgggaagt ggaatcatct gtaaatgaga
      181 ctgtaagggg agcagatcct gatgttatat ttgccgtgaa acttgcactg acgtcactgc
      241 atatgggtcc gggtggagga atattcacag ggacgaaata ttctgtaagg aggagagctt
      301 ctgcagaacc ccccctgtag ataagctgga catattcagg catccccggt ccttcatagg
      361 tgacaacgag agcctttccc actgtccagg gagtcttcgt gatatcccac gttgcgcttt
      421 cagatgtacc atcttcgttt ctgatggtaa tttttgagtg agggacttca gggacgttat
      481 taacagaaat aatggtctgt tcttctttca acgcatctcc accattgtgg tagagcagga
      541 ttgtattact cgtattgctt gcaagcgcgg aaaggtgcgg tatctcttcg ggtggtggat
      601 tggaaagaac aacaacggcc acgattgcca ttgcagtgat gacaagcccg acgaggagga
      661 ttgccccaat cagttccgat atacccgcat tgaccctctc gtctccaggc atccctgtaa
      721 ctcctttatg cacttttcaa atactctatg aatgcctttc atataaatga acatcgtccc
      781 tgcaccccgt ctccggggag gggaaaccgg taatcagggg aaatacttct ggacgagcat
      841 tgtctccctc ccgtcgtttc cccgggaaac gaccatgaca gtgcggggag atgaaactgc
      901 aggtaattcg agtgccgttc ccgggcggaa tggagtacta tccggaatgg ggacgaattc
      961 ctgggtccga tcggttccat ccacgtagat cctgtaggaa ccttccggaa gcacatcccc
     1021 gcctgcatgg attatggtga tgatgctgtt ttcgtacccg ataacaaatg agacagcagg
     1081 tacctgggag acgttgatat tcgatagaat tgtgacgcca aggatgctga ttgcaaggct
     1141 gatgactgcg atcaggagga gtacaccgat taattccgag actgctgaat cgctggcatt
     1201 tccttccctc atagggcaac cgtctggaga ttcacactca ggttgacgcg ggtatagtcc
     1261 aggaataatg aataattatc aggatcacga acggtaaact ggaccgtgtt tccggtttgg
     1321 actggtgcag gtatccacgc aggggggaaa tcttcgctca aagctgcctg cctgatgcgg
     1381 gagaaagtct ggttccacat ctgtgcggtt tgctgatcct gtgcactgat gatgaaagtg
     1441 acatttcttg cattgggtat ccccgtggca agtttttgtt gatcgatggt attctcctgg
     1501 agcgatgtca gggtcgagac gacctgaaca ggggatgacc ctccgatatt tcccgaacca
     1561 tcgatgaaaa tgtcgaccat ccgtacagtg ggcagaccgg ttttgttggt cacactgata
     1621 aggggaatca ctttcgatac cattccatcg ggctgcctga ggaagacgcc ccccagctgg
     1681 taatagtaat cctgctggat ccagtagtta ttgctggacc ggaattcgag ggaatccatg
     1741 gggtgtgaga atacaatttc tgcagaattg tagccaacct ggacaggata gaagacttgg
     1801 atatttggag tactgaatat gggtgttctt attttcaacg gataatccaa agcctctgca
     1861 agaccatatg catcatccag aaggtcaatg gtgtagttcc tgttattgat aatttcagga
     1921 ataatagtga gattcgagaa agttgcatta tcgttcttta cgagggtcat ggtcagggca
     1981 ggacgagaga cacctaatcc ctggaccatt aatgtccaat taggtactag aattgtgttt
     2041 atccatgatg caatatcagg aacgttaggt tgttccagag gaggtaatac acttggcgcc
     2101 ggagagtttg tacctgttga aacaataatt ggcgtgatgt taagtacgat ataccattga
     2161 ggattggggt tatccgggta aattattact ccaccatgct catcgcgatt tgttgtcttt
     2221 aactggatgt ataaatgatc tggttcacgg tatatagggt taatatttgg ttgcatattc
     2281 ccaggaaatc cctgcacaag tacgtcagca ttgagggtga tgtcctcccc cctttcgttc
     2341 accactatca tcccgctcga gggatagggc tggaagacag gaacgacaaa tgccccctgg
     2401 gtgagtcccg tgaccgttcc gagagtaaac gtattcgata tgggcacgtt ttcctggcca
     2461 ttgatccaga gcgaatcgat tgtcgtcttg tattgcaaaa actggtcgtt tacctgcgcc
     2521 atgtgcttaa tctcaagttc cctcccctgg gccgggacca cgtaagtgat atagagggat
     2581 gcaactgctg cgatgatccc caggatcagg atgaacccga tgacctcgga gaggccctcg
     2641 tcggtgagcg gggcag
//
LOCUS       DAOOJU010000075         2536 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_32044_length_2536_cov_15.406288, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000075 DAOOJU010000000
VERSION     DAOOJU010000075.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2536)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2536)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2536
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_32044_length_2536_cov_15.406288"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1625)
                     /locus_tag="PK679_09245"
     CDS             complement(<1..1625)
                     /locus_tag="PK679_09245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56174.1"
                     /translation="MAGGEIARALSLLFSPGSVVELRAITEEGMASGYFDDPVALGEA
                     AGTLDAAGTTGIYVTLNEVNPALLSRRSNRVRMRLSKKDATTADGDIIRRRWFPLDID
                     PVRPSGISSTDAEHRAALDRAGRIAAFLAERGWPAPILADSGNGAHLLYRIDLPNDDA
                     SRDLVKRALAALDTLFSDGTCTVDTSNANAARIWKLYGTTSRKGDHTPDRPHRKARIL
                     DAPDHAGVAGRGLLEALAATLPAPPARKVSPARGTAIDLRSWLSGHGIGIAAEKPYAG
                     GTLFVLEECPFSDAHRDGAFAIQFGNGAIHAGCHHASCGGGSQRWKELRAKFGRGEGH
                     APAVPPAEPVPGEPAPPADLPGHAEALSLLQHGDPKEAMLRAFALDHEGDEVVAECLV
                     MSLASRSVANTNGLHVSVTGESGKGKSHAFATMLRQVPERFRLEGAMSNKALFYLEGM
                     QPGSVIVLDDHALSEEIQEILKSATTCFSEPIGYRTVTRDRKMQVCTIPERCVWWVSK
                     VEGVGDDQVQNRMLTCWIDDSEEQDARVLARILA"
     gene            complement(1607..1828)
                     /locus_tag="PK679_09250"
     CDS             complement(1607..1828)
                     /locus_tag="PK679_09250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56175.1"
                     /translation="MMPLVRITCTPGPSLPACPACGCRSWDRQGQELSCRACAVRVTL
                     ADDPGTDRVVLVIEGPTLSPGGPAWQAGR"
     gene            complement(1825..2016)
                     /locus_tag="PK679_09255"
     CDS             complement(1825..2016)
                     /locus_tag="PK679_09255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56176.1"
                     /translation="MWREQADGGMSERKVCPFMSDPRRIVLCQGKTCAAACPVRSGDG
                     TLWRCGLVGDDAGGEGGMP"
     gene            complement(2006..2395)
                     /locus_tag="PK679_09260"
     CDS             complement(2006..2395)
                     /locus_tag="PK679_09260"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56177.1"
                     /translation="MIPTSDHRLSPRRTRRYRCRTAEYEARSVLREMAFPVVIRSTDP
                     AFPGSLVAWSPAGVVHVFSVVSTRRAIAGVAEAASLFSGEIADLRGIPRATGASVNLW
                     IRSGHKSWHLYRVFPGGIAETGVPDVA"
BASE COUNT          371 a          860 c          920 g          385 t
ORIGIN      
        1 gcgaggatcc gggccagcac gcgggcgtcc tgctcctccg agtcatcgat ccagcaggtg
       61 agcatcctgt tctggacctg atcgtcccca acgccctcga ccttcgagac ccaccagacg
      121 caccgctcag ggatggtgca gacctgcatc ttgcggtccc tggtgaccgt ccggtacccg
      181 atgggttcgg aaaagcacgt ggtcgccgac ttgaggatct cctggatctc ctcggagagg
      241 gcatggtcgt cgagcacgat cacgctgccg ggctgcatgc cctcgaggta gaagagggcc
      301 ttgttgctca ttgcgccttc cagccggaag cgttccggga cctggcggag catggtcgca
      361 aaggcgtggc tcttgccctt gccgctctcg cctgtcacgg agacgtgcag gccgttcgtg
      421 ttggcaacag accgggaggc aagcgacatg acgaggcact cggccaccac ctcgtcgccc
      481 tcgtggtcca gcgcgaaggc ccggagcatc gcctccttcg ggtcaccgtg ctgcaggagg
      541 gagagcgcct ccgcgtggcc ggggagatcg gcaggagggg ccggttcccc gggcacgggt
      601 tctgccgggg gtacggcggg ggcatggcct tctccccgcc cgaactttgc ccggagttcc
      661 ttccagcgct gcgatccgcc cccgcaggag gcgtggtggc acccggcatg gatggccccg
      721 ttcccgaact ggatggcaaa cgccccgtcc cggtgggcat ccgagaaggg gcactcctcc
      781 aggacaaaga gtgtcccgcc cgcgtagggc ttttctgccg caatcccgat gccgtgcccg
      841 gagagccagg accggaggtc gatcgcggtc ccgcgggccg ggctgacttt tcgggccggc
      901 ggggccggga gagttgccgc gagggcttcg aggaggccgc ggccggcgac cccggcgtgg
      961 tccggggcgt cgaggatccg tgccttccgg tgggggcggt ccggcgtgtg gtcgcctttc
     1021 cgcgaggtcg tgccgtagag cttccagatg cgggccgcgt tggcgtttga ggtgtccacg
     1081 gtgcaggtgc cgtccgagaa cagggtgtcc agggctgcaa gagccctctt cacgaggtcc
     1141 cgggatgcgt catcgttggg gaggtcgatc cggtagagca ggtgggcccc gttcccggag
     1201 tccgcgagga tgggtgcggg ccacccgcgt tccgcgagaa acgcggcgat cctgcctgcc
     1261 cggtcgagtg ccgcccggtg ttcggcatcg gtcgaggaga tgcccgaggg ccggacgggg
     1321 tcgatgtcga gggggaacca gcggcggcgg atgatgtcgc cgtctgccgt ggtcgcgtcc
     1381 tttttcgaga gccgcatcct gacgcggttt gaccgccgcg agaggagtgc cgggttcacc
     1441 tcgttcagcg tgacgtagat gccggtcgtg ccggctgcat ccagcgtgcc ggccgcttcc
     1501 ccgagcgcaa ccgggtcgtc gaagtacccg gatgccatcc cctcctccgt gatcgcccgg
     1561 agctcgacga ccgatccggg ggaaaagagg agggagaggg cacgggctat ctccccgcct
     1621 gccatgcggg tcctccgggg gagagggtgg ggccttcgat gacaaggacg acccggtccg
     1681 tcccggggtc atcggcaagc gtcacccgga cagcacaagc ccggcaggac aactcctgcc
     1741 cctgccggtc ccacgagcgg cagccgcagg ccgggcaggc gggcagggag gggccgggcg
     1801 tgcacgtgat ccggacgagc ggcatcacgg catcccccct tcccctccgg cgtcgtcccc
     1861 gaccagcccg caccgccaga gcgtcccgtc cccggaccgg accgggcagg cggcggcaca
     1921 ggtctttccc tggcagagga cgatccgccg ggggtccgac atgaaggggc agaccttgcg
     1981 ctccgacatg ccgccgtccg cctgctcacg ccacatccgg cacccccgtc tcggctatcc
     2041 cgccggggaa gaccctgtac aggtgccagg atttgtggcc ggaacggatc cagaggttga
     2101 ccgacgcgcc ggtcgcccgt gggattcccc gcaggtccgc gatctccccg gaaaagaggg
     2161 acgcggcctc cgcaacgccc gcgatcgccc gccgggtcga gaccacggaa aagacgtgga
     2221 ccacgcccgc cggggaccag gcgaccaggc tcccggggaa ggcagggtcc gtggaccgga
     2281 tcacgaccgg gaaggccatc tcccggagga ccgaccttgc ctcgtactcc gcggtccggc
     2341 accggtagcg cctcgttctc cgcggcgaca gcctgtggtc actcgtgggt atcatccggg
     2401 tcaggctcct ggaaacgggg gttggccggg cacgcccggt ccgggcaggg accgggggac
     2461 ctgcacgcga gggtcagcca gctgccctcc tttccgcggg agaggtgggg gcacgcgtgt
     2521 gccatcagga ggcctc
//
LOCUS       DAOOJU010000076         2475 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_33137_length_2475_cov_5.622727, whole genome shotgun sequence.
ACCESSION   DAOOJU010000076 DAOOJU010000000
VERSION     DAOOJU010000076.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2475)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2475)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2475
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_33137_length_2475_cov_5.622727"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            12..>2475
                     /locus_tag="PK679_09265"
     CDS             12..>2475
                     /locus_tag="PK679_09265"
                     /inference="COORDINATES: protein motif:HMM:NF024270.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3821 domain-containing protein"
                     /protein_id="HPC56178.1"
                     /translation="MKLRHKVLFSLVIGIALLAVVMPVSAQLNVVPQNGTVLLGEEGL
                     DVTAAVGSATHLGWWAPGTDYSTPPDREIDLSGYVLTNFNIDDGPSSPFIGTESKGAW
                     WRMNGSGMTNPTEQAFSVVAPQATLKIKNLNYGGISGADITGGTAMIGDVLDFELNPS
                     TLHYIFNRDPSATFNCKIVVRNPGGVTYTKLWSPTPPTPSQRDLVNLDVATTPFYWSS
                     GNGTSGDITKGWKTDAIDPVTSFPVYSAGDYQVHIECNENKLGFSGTIQTVTLEEEQP
                     ILTVSPSSLIRGNKFYTTIKGIPNTYYVIWIKDCVACPNGCCDEPMSGACCDRPPMIV
                     DGQEGVIFGDQYGTFWANCPHTMGSICDMYSSCVPCGCGQINGDGDGQGDYYTLGDTL
                     LLWCGCLCTEKLYGIVPHSPEGGKYYYALVYTDENGERTVEWQTSTCTAPSTYKIHTQ
                     RWIENDVCELDTDRPYAEACVNVQKGVVTINTEVCGQPASESYLGETVRIYGTNTDSR
                     TTYLFITGPCQSCQGENMTVTNTVVNGDPSTFTKVNVKSDGTWEYYWYTRNLAIDLGE
                     YTIYAASMPNDAPALEGVACTECSGVNVSCAAWAKAPFTFLEPDLTGVISPKVLKIVC
                     CTPPTITVSGSALGMRGEAIGQQYNTVPLGFWVFGENKVAGQKYVFDVVYPDCNTGTY
                     SINLQDYINTLALEPGTYTVVVQHPMYNHRLDIIPETWICDQSDWCPWLRLANFAYLL
                     LDEVWYPDVNKKYVVTASPVRWSKLFVIDGPDRLAGTAALNALLEGFNDRNIDDKVIV
                     LTFKVESNTALQADFSGSPTYGP"
BASE COUNT          590 a          694 c          680 g          511 t
ORIGIN      
        1 ggtggtgcaa aatgaagctt cgacacaaag tgctcttctc gttagtgata ggtattgccc
       61 ttctcgcagt ggtgatgccg gtttcggcac agctgaacgt tgttccccag aacggaacag
      121 tcctcctcgg ggaagaggga ttagacgtga ctgctgccgt ggggtccgca acccacctgg
      181 gatggtgggc accgggtaca gattactcaa cacccccgga tagggagatt gatttgagcg
      241 ggtacgtgct cacgaacttc aatatcgacg atggcccgag ctcccccttt atcggtacgg
      301 agagcaaggg tgcatggtgg agaatgaacg gttcaggaat gacgaatccc accgagcagg
      361 ctttcagtgt cgttgcccct caggcaacac tgaagatcaa gaatctgaac tatggtggga
      421 tctccggagc ggatatcacc ggtggcacag cgatgattgg tgacgtcctt gacttcgaac
      481 tgaacccgtc gaccctgcat tacatattca accgggatcc ttcagcaacc ttcaattgca
      541 agatagtggt ccgaaacccg ggtggtgtca catacacgaa gttatggtcg ccaacacccc
      601 cgactccgtc acagagggat ctggtgaacc ttgatgtcgc gacgactccc ttctactggt
      661 cctccggaaa cgggacgagt ggtgatatta ccaaaggctg gaagaccgat gcaatcgacc
      721 ctgtaaccag tttccctgtc tacagcgcgg gagactacca ggttcacatc gaatgcaacg
      781 agaataaact cgggttcagc ggcacaatac agacagtcac tctggaggag gaacaaccca
      841 tcctgaccgt cagtccctcc tccctcatcc gtggaaacaa gttctacacg accatcaagg
      901 gtattccgaa cacctattac gtcatctgga tcaaggactg tgttgcctgc cccaacgggt
      961 gctgtgacga gcccatgtca ggggcctgct gtgaccggcc gccgatgata gtcgacgggc
     1021 aggagggggt catcttcggt gaccagtacg ggacattctg ggcaaattgt ccccacacca
     1081 tgggaagcat ttgtgacatg tactcatcct gtgtcccctg cggttgtgga cagattaacg
     1141 gagatggaga tggacaagga gattactata ctctcggtga tacgctgctg ctttggtgcg
     1201 gttgcctgtg cacggagaag ctttatggaa tagttccgca ctccccagaa ggcggaaaat
     1261 actattacgc acttgtctac acggacgaaa acggcgaaag gactgttgaa tggcagacca
     1321 gcacatgcac cgccccctcg acatacaaga tccacaccca gcgctggata gaaaacgatg
     1381 tgtgtgaact cgataccgat cgtccctatg cagaggcctg cgtgaatgtc cagaagggtg
     1441 ttgtcaccat taacacggag gtctgtggcc agccggcaag cgagtcctac ctcggcgaga
     1501 ctgtcaggat ttacgggacg aataccgact cccgcacgac gtacctcttc atcaccgggc
     1561 cctgccagag ctgccagggc gagaacatga cagttacgaa caccgtcgtg aatggagatc
     1621 catcgacgtt cacgaaagtc aatgtcaagt cggacggtac ctgggagtat tactggtata
     1681 cgaggaacct cgcgatcgac cttggtgaat acaccattta tgcagccagc atgcccaacg
     1741 acgcgccggc cctcgaagga gttgcctgta ccgagtgcag cggtgtgaac gtgtcctgtg
     1801 ctgcctgggc gaaggcaccg tttaccttcc tcgaacctga cctcaccggg gtgatcagtc
     1861 cgaaagtgct gaagatcgtc tgctgtacac cccccaccat caccgtgagt ggttcggccc
     1921 tcggaatgag gggagaggcc atcgggcagc agtacaacac ggtaccgctg ggattctggg
     1981 tatttggcga gaacaaggtt gccggccaga agtacgtgtt cgatgttgtt tatccggact
     2041 gcaacacggg aacgtattcc atcaaccttc aagactacat caacactctc gcactggaac
     2101 cgggaaccta caccgtcgtc gtccagcacc ccatgtacaa ccacaggctg gacatcatcc
     2161 ccgagacatg gatatgcgac cagtccgact ggtgcccgtg gctccggctt gcgaacttcg
     2221 cctacctgtt gctggacgag gtctggtatc ctgacgtcaa caagaagtac gtggtcacag
     2281 catcacccgt caggtggagc aagctcttcg tcatcgacgg gcctgaccgg cttgccggaa
     2341 cagcagcact caacgccctc ctcgagggat tcaacgaccg gaacatcgat gataaagtta
     2401 tcgtcctgac cttcaaggtt gagagcaaca ctgccctcca ggcagacttc tccggttcac
     2461 cgacgtacgg gcctg
//
LOCUS       DAOOJU010000077         2449 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_33641_length_2449_cov_15.564327, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000077 DAOOJU010000000
VERSION     DAOOJU010000077.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2449)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2449)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2449
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_33641_length_2449_cov_15.564327"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..>535)
                     /locus_tag="PK679_09270"
     CDS             complement(<1..>535)
                     /locus_tag="PK679_09270"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56179.1"
                     /translation="MDENFRTTYVNPRMASLLGYTPEEMLGREITSFMPESELADSRE
                     KFRDRMAGKPGEYERRVLHRDGSVRIMHVSATPILDSNGTFRGSFAMLTDITEKKQLA
                     DNFQKEHLELLAAYEQIAATEEELRRMLEELREYQETLAKSEEKFRRIVETAHEGIWE
                     MDENFRTTYVNPRMASLL"
     assembly_gap    536..635
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<636..1881)
                     /locus_tag="PK679_09275"
     CDS             complement(<636..1881)
                     /locus_tag="PK679_09275"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56180.1"
                     /translation="MHHSKAYSVLYIDDDKDLLLLGKAFLERMGDFSVEVTGSAKEGL
                     ALLAEKKFDAVISDYQMPSMTGLDLLKAIRAKGDGIPFIIFTGRGREEVVIEALNAGA
                     DFYLQKGGEPKTQFVELAHKVRQAVTRRRAEMMVVESRKRLADIIDFLPDATFAIDRE
                     GKVIAWNRAMEEMTGVSATEVLGMGDYRHGLAFYGEPRPMLIDLVLSPREDFEREKYL
                     FTRREGTTLTGETILERKNGTVHHYWGKASRLYDENGEPAGAIESIRDITDRVRAEEH
                     SRILAQVLDIAPASITIHDTGGTFLYANQKTFEIHGYTRDEFMRMRLENIDTPESAAL
                     IAPRMQEIMRDGEGSFTVTHRTKGGGTIPLHVTVKLASWSGRPAMISVATDLSERLKA
                     EEEIRKREEQFRRIVETAHEGIW"
     gene            1995..2327
                     /locus_tag="PK679_09280"
     CDS             1995..2327
                     /locus_tag="PK679_09280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56181.1"
                     /translation="MTELGPMPDASHIIRAAGLMDWVLPGRKYPGVLPEGVRDYYCYT
                     RDGGHSLLVVLENEYRHGAPPERFVVPAPVKMVLREGYRLRDGYLWANLPYTKDIGLA
                     VRDEDIEY"
BASE COUNT          393 a          711 c          716 g          529 t
ORIGIN      
        1 aggagcgatg ccatccgggg gttgacgtag gtcgtccgga agttctcgtc catctcccag
       61 atcccctcgt gggccgtctc cacgatccgg cggaacttct cctcgctctt cgcgagggtc
      121 tcctggtact cccggagttc ctcgagcatc ctgcgcagtt cctcttctgt tgcagcgatc
      181 tgctcgtatg cagcgagaag ttccaggtgc tctttctgga aattatccgc aagttgcttt
      241 ttctccgtga tatcggtaag catggcaaag gatccccgga atgtgccgtt gctgtcaagg
      301 atcggtgtcg ccgagacgtg catgatgcgg accgacccgt ccctgtggag taccctgcgc
      361 tcgtattctc cgggttttcc cgccatccgg tcccggaatt tttctctgct gtccgcaagc
      421 tcgctctccg gcataaaaga ggtgatctcg cggcccagca tctcttcggg ggtgtacccg
      481 aggagcgatg ccatccgggg gttgacgtag gtcgtccgga agttctcgtc catctnnnnn
      541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnncccag atcccctcgt gggctgtttc
      661 cacgatccgg cggaactgct cttccctttt cctgatctcc tcctcggctt tcaggcgttc
      721 ggaaaggtcg gttgcaacgg agatcatcgc cggcctgccg gaccagctgg cgagtttcac
      781 ggtcacgtgg agggggatag tccccccgcc cttcgtcctg tgggtgacgg taaaggaccc
      841 ctccccgtcc cgcatgatct cctgcatgcg gggtgcgatg agtgccgcac tctcgggagt
      901 gtctatgttc tcgagcctca tcctcatgaa ctcgtcgcgg gtgtacccgt ggatctcgaa
      961 agttttctgg ttcgcataca ggaaggtgcc cccggtgtcg tggatggtga tcgatgccgg
     1021 ggcgatatcg aggacctggg cgaggatgcg ggagtgttcc tcggcccgga ccctgtccgt
     1081 gatgtccctg atcgactcaa tcgcgcctgc cggttccccg ttctcgtcgt agagccggct
     1141 ggctttcccc cagtaatggt ggacggttcc gtttttccgt tcaaggatgg tctcgccggt
     1201 gagggtcgtc ccctcgcggc gggtgaacag gtatttctcc ctctcgaagt cctcccgggg
     1261 ggaaagcacg aggtcgatga gcatcgggcg cggttcgccg tagaaggcaa gcccgtgcct
     1321 gtagtccccc atgccgagga cttcagtggc cgaaacgccg gtcatctcct ccatggccct
     1381 gttccatgcg atcacctttc cctccctgtc gatggcaaac gtagcgtcgg gcagaaaatc
     1441 gatgatgtcg gcgaggcgtt tgcgggactc gaccaccatc atctcggccc gccgcctggt
     1501 cacagcctgg cggaccttgt gggcgagttc cacgaactgg gtcttcggtt cccccccctt
     1561 ctggaggtag aagtccgcgc ccgcgtttaa cgcctcgatg acgacttcct cccgcccccg
     1621 gcccgtgaag atgatgaagg gaatgccgtc tccctttgcc cggatggcct tgaggaggtc
     1681 gagccccgtc atggacggca tctggtagtc cgagatcacg gcatcgaatt tcttttcggc
     1741 gaggagggca aggccttcct ttgccgaacc ggtcacctcg acggaaaagt ctcccatgcg
     1801 ttcgaggaat gcctttccca ggaggagaag gtccttgtca tcgtcgatgt agaggacgga
     1861 ataggccttg gaatgatgca tttctggaga aaaataaaca ctttggattt ataaagagtt
     1921 ccctgttccc ccatgccatt ctccggtcag cgtacctgct ccattttccc gtaaagccag
     1981 gtttatcagg gaagatgacc gagcttggac ccatgcctga tgcatcgcac attatcaggg
     2041 cggcggggct tatggactgg gtgctccccg ggaggaagta ccccggcgtc ctgccggaag
     2101 gggtccgcga ctattactgc tacacgcggg atggcggcca ctcgctcctc gtcgtgctcg
     2161 agaacgagta ccggcacggc gctcccccgg agaggttcgt tgtccctgcc ccggtgaaga
     2221 tggtcctccg cgagggatac cggttgcggg acggctacct ctgggcaaat ctgccctata
     2281 caaaggatat cggtcttgcc gtcagggacg aggacatcga gtactaggaa aaggggcagg
     2341 gcctgccggt gaaccggccg gggcaggggg caggaccccg gatattccgg cagtctgtgc
     2401 cgggcttggg ggtacccgct ctctccgtgg agaccatgga aaaagccag
//
LOCUS       DAOOJU010000078         2393 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_34787_length_2393_cov_13.278443, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000078 DAOOJU010000000
VERSION     DAOOJU010000078.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2393)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2393)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2393
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_34787_length_2393_cov_13.278443"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            284..838
                     /gene="thpR"
                     /locus_tag="PK679_09285"
     CDS             284..838
                     /gene="thpR"
                     /locus_tag="PK679_09285"
                     /inference="COORDINATES: protein motif:HMM:TIGR02258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008664 - 2'-5'-RNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HPC56182.1"
                     /translation="MDRLFIAVDLPRDIRESLGAVQALLNKSSARLTHVDPAIIHVTL
                     KFIGDTPPEKTRAVAEALGKMRAAPFSVRVRGISGNNPRRPRVIWARVEDGGKCGLLH
                     AGVEDLLSPLGIQRDDRPFVPHATVARVREFHPDLPGIIRPLSDRDFGGGVIDRIVLK
                     KSTLTPRGPVYQDITEVPLEEDSP"
     gene            819..2192
                     /gene="cca"
                     /locus_tag="PK679_09290"
     CDS             819..2192
                     /gene="cca"
                     /locus_tag="PK679_09290"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HPC56183.1"
                     /translation="MKKTALEEEVLSLIRPTPEEVSHINGVAQRILDRIRADGRAEGM
                     VVGSVARGTWIHGDRDLDIFLLFDPSLSREELEEQGLSLARAIAAAEAERFREKYAEH
                     PYINASIDGLDVDLVPCYRVESACSIKSAVDRTPFHTVYIRERIQPFIDDVLLLKQFA
                     KAGGIYGSDQMTEGFAGYLCELLVLSYGGFLPLLEAASRWRPGIIIDPAGHRARDFPE
                     PLVVVDPVDPKRNVSASVSLTRMCEFIELARGYIGEPGRAFFFPPPRPVLSVDEAACL
                     LSRRGTFLYAIVLPTPPYIEDIVVPQLRKSLDAIRGLLDRHGFSVNRADCEMHEETSM
                     LLFELLVEELPSVVRHAGPPVWNHVNASRFSSKYLPCSENELFSGPFIEDGLLIVEKR
                     RAYTRAGDLLRSPEVLQVALGKHVKQAMERSYTVHKGIECYREEFAPFISGFLRKYSP
                     MTWLARH"
BASE COUNT          443 a          765 c          677 g          508 t
ORIGIN      
        1 cccgctcgct gaaagagaga ccccgccctt tcagaaattc cttcaggatc tcgcaattcg
       61 ggcatgattc gagtgaatag acgataatat cgtgagaacc gggcatgaat gtcccccgct
      121 tgtcagcttc atgtcagtaa ttgttcttcg ggaaaaaata tttgctgatc ctgcctcaat
      181 tgtaccagaa ggaacgggga tttttttgcg atcaggtagt ttaacgcggg aaattgatat
      241 gggatacgct gccggcacaa aacaggagaa aggctgaata tacatggacc ggctcttcat
      301 cgcggttgac ctcccacggg atatcaggga atccctcggg gctgtccagg ctctcctgaa
      361 taaaagcagc gcccggctca cgcacgtcga ccctgccatc atccatgtca ccctcaagtt
      421 catcggtgat acaccgcccg aaaagacgcg ggctgttgcc gaagcgcttg gaaagatgag
      481 ggcagccccg ttttcggtca gggttcgcgg gatctccggg aacaaccccc gtcgtccccg
      541 ggtcatctgg gcgcgggtcg aggatggggg gaaatgcggt ctcctccatg caggggttga
      601 agacctcctc tcccccctcg gtatccaaag ggacgaccgg ccctttgttc cccacgccac
      661 ggtcgcgcgt gtccgcgaat ttcaccccga tctccccggg attatccgcc cgctctcgga
      721 ccgcgatttc ggcggggggg tcatcgacag gatcgttctc aagaagagta ccctgactcc
      781 ccggggaccg gtttaccagg acatcacgga ggtcccgctt gaagaagaca gcccttgagg
      841 aggaggtact ctcgctcatc aggcccacgc cggaagaagt ctcccatatc aacggggttg
      901 cgcagaggat actggaccgt atccgggctg acggtcgtgc ggaagggatg gtcgtcgggt
      961 ctgttgcccg cgggacgtgg atccacggcg atcgggatct tgatattttc ctccttttcg
     1021 acccgtccct ttcccgggaa gaactcgagg agcagggtct ttccctcgca cgggccatcg
     1081 ccgcggcgga ggccgaaagg ttccgcgaga aatatgccga gcacccgtac atcaatgcga
     1141 gcatcgacgg gctcgatgtc gacctggtcc cctgctacag ggtggagtct gcatgctcca
     1201 tcaagagcgc cgtggaccgc actcccttcc acacggtcta cataagggag cggatccagc
     1261 cgtttatcga cgatgtcctc ctcctcaagc agtttgcaaa ggcagggggc atttacggct
     1321 ccgaccagat gacggaaggg tttgccgggt acctctgcga gctcctcgtc ctctcgtacg
     1381 gcggttttct gcccctcctc gaagccgcgt cacgctggcg gcccggcatc atcatcgacc
     1441 ccgcgggtca cagggcccgg gactttcccg aaccgctcgt ggtggtcgac cctgtcgatc
     1501 cgaagcggaa cgtctctgcc tcggtctccc tgacccggat gtgcgagttc atcgagcttg
     1561 cccgcggtta catcggggag ccgggacgcg cgttcttctt tccccctccc cgtcccgtgc
     1621 tctccgttga cgaggcggcc tgtctccttt cccggcgggg gacgttcctc tatgcgatcg
     1681 tcctccccac tccgccctac atcgaggaca tcgttgtccc ccagctccgc aagagtctcg
     1741 atgccatccg gggactcctc gaccgccatg gtttttccgt gaacagggct gactgcgaga
     1801 tgcacgagga gacctccatg ctcctcttcg agctcctcgt cgaggaactc ccttccgtcg
     1861 tccgccatgc cggtcccccg gtctggaacc acgtcaatgc atcccggttc tcctcgaagt
     1921 acctgccatg ctccgagaat gaactctttt ccggcccctt catcgaggac ggcctcttga
     1981 tcgtcgagaa acggcgggcg tatacccggg ccggcgacct gctccgctcc ccggaagtcc
     2041 tgcaggtcgc cctcggaaag cacgtgaagc aggcgatgga gcggtcgtat accgtccaca
     2101 aggggatcga atgctaccgc gaggagtttg ccccgttcat ctccggtttc ctgcggaaat
     2161 actccccgat gacatggctt gcgaggcatt gaccggaccg ggcctgcagc cggaatccgg
     2221 gagatcctcc tctctcccct tttttaccgg gtcaggaatt gaaacaggct ttccggcatg
     2281 ggaaaggttt gatatcttta taagatgttc cggcacacat actccatagt tcccatgcct
     2341 gccccgctca ccgacgaggg cctctccgag gtcatcgggt tcatcctgat cct
//
LOCUS       DAOOJU010000079         2296 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_36865_length_2296_cov_3.077198, whole genome shotgun sequence.
ACCESSION   DAOOJU010000079 DAOOJU010000000
VERSION     DAOOJU010000079.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2296)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2296)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2296
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_36865_length_2296_cov_3.077198"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..>2296
                     /locus_tag="PK679_09295"
     CDS             <1..>2296
                     /locus_tag="PK679_09295"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC56184.1"
                     /translation="YQTAGTYTVTLTVTGAGGTSDTNGEIRVNAPSGIPAPIADFSAS
                     PRSGTAPLTVQFTDLSNGTITSWAWDFDSDGTVDSTDQNPSYVFGSKGIYAVTLTVAG
                     PGGENSTKKANYIVATAPSKTITADFTADPKTGHAPLPVQFTDTSSGTITSWSWDFDN
                     DGNTDSTDQNPVFVYHEAGSYSVTLTVTGPNGVNTLKKTDFISVMDTEYTCDLSIGGL
                     PTPIGATAFALEPNTVKIFKVGNPGPDPSPETELELKSSDGFTGRVHVPVIEPGDEVT
                     LVITDPTIRSTVGTKVTYTATIDPDNKVIETNENNNVKSRSVEVKYNGYKGARFWGGQ
                     DDIQTVAILDLHGDIIHSFGDSQYRSGSFGSGWNSHTVTWTADQLDIPDDATVRLVRL
                     YVPYTWDNAHIAPDKVSVKFNGKTIPYQHWYHDVSNFGAYWDHVYGLLTYNVTGEFKK
                     NDINKVIFSRQGDPLFTKISMYGFTLAVVYEDPDEPRRMIFLNEGFDLLGASEDDYGT
                     TEEEATAYIRFTGPSIDLSDVRSANLITFVASGAAQEPGREGEGNLIVNGKTIAKDVW
                     DYGGTIGVDTGEDGTTQVAVDSRDITDILVSTENEVGIQSTEGITPSMAPIQAFLVVT
                     MDDDSASSSTGGGSSSGGGSSGAGTSHGSSPASQTDESPNQTRTMAPDTPVPGVEVIE
                     KVETSTREFTSSTTVPVAANNSNQSSKEHENPVRPRKRGFPPIIGGIVIGIGSASAIG
                     LYYSIQEIRTRYRYLVAALLTGIIL"
BASE COUNT          595 a          660 c          589 g          452 t
ORIGIN      
        1 taccagacag ccggaaccta taccgtcacc ctgacggtca ccggcgcggg ggggacatcc
       61 gatacaaacg gagagatcag agttaacgcc ccgtcaggga tacctgcccc gatcgctgac
      121 ttctccgctt ccccacggtc agggaccgcc cccctgacag tccagttcac ggacttgtcc
      181 aacggcacca tcacgtcgtg ggcctgggac tttgacagcg acggcaccgt cgacagcacc
      241 gaccagaacc cgagttacgt gtttggaagc aaagggatct acgccgtcac cctcacggtt
      301 gcaggtccgg ggggagagaa cagcacgaaa aaggccaatt acattgtcgc gacagccccc
      361 tcgaagacaa ttactgcaga ttttaccgct gacccaaaaa ccggacatgc acctctcccg
      421 gtgcagttta ccgatacatc gtcaggaacc atcacttcct ggtcatggga ctttgataat
      481 gacgggaata cggacagcac cgaccaaaat ccggtcttcg tctatcacga agccggctcc
      541 tacagtgtca cactcaccgt aacaggaccc aatggtgtga acacccttaa aaaaacagat
      601 tttatctcgg tcatggatac tgaatatacc tgtgacctct ccatcggggg actcccgacc
      661 cccatcgggg caacggcttt tgcactggaa ccaaacactg tcaaaatttt caaggtgggc
      721 aatccgggac cggacccctc acccgagacc gaactggaac tgaaatcatc cgacgggttc
      781 accggaagag tccacgtccc cgtcatcgag ccgggcgatg aagtgaccct cgtcattacc
      841 gacccaacaa ttcggagcac cgtggggaca aaggtgacct atactgcaac aatcgacccg
      901 gataacaagg ttatcgagac caatgagaat aataacgtca agtcaaggtc agtcgaggtc
      961 aagtacaacg ggtacaaggg tgcacggttc tggggtggac aggacgacat ccagactgtc
     1021 gccatccttg acctccacgg cgacatcatc cattccttcg gtgacagcca atacaggtcc
     1081 ggcagtttcg gcagcggctg gaacagccac actgttacat ggacagcaga ccagctcgac
     1141 atcccggatg atgccacagt caggcttgtc aggctctatg tcccctatac gtgggacaat
     1201 gcgcacattg ccccggataa ggtttctgta aagttcaatg gaaaaacaat cccttaccag
     1261 cattggtacc atgatgtctc caacttcggt gcctactggg accatgtcta tggactcctc
     1321 acgtacaatg taacaggcga attcaagaaa aatgacatca acaaggtcat cttttcacgg
     1381 cagggtgacc cgctcttcac caagatctcg atgtatggtt tcacactcgc cgtggtctat
     1441 gaagacccgg acgaaccacg caggatgatc tttttgaacg aggggttcga tctgctcggt
     1501 gcaagcgagg acgattacgg gacaaccgag gaggaggcaa cagcctatat ccggtttaca
     1561 ggcccttcca ttgacctttc ggatgtaagg tcagccaacc tcatcacctt cgtcgcatcg
     1621 ggagccgcac aggagcccgg tcgtgaagga gagggtaacc tcatcgtgaa cggaaagacg
     1681 atcgccaaag atgtctggga ctatggaggt accatcggcg tcgatacagg tgaagacggg
     1741 acgactcagg tcgcagtgga cagcagggac atcaccgata tcctggtttc gaccgagaac
     1801 gaagtcggca tccagagtac cgagggtatt accccttcta tggcaccgat tcaagcattc
     1861 ctcgttgtga cgatggatga tgattcagca tcatccagta caggcggggg atcttcgtca
     1921 ggcggaggtt cttcgggggc cggaacttcg catggaagtt ctcctgcatc ccagactgat
     1981 gaatctccca accagacccg gacaatggct ccagacactc ccgtaccagg ggtcgaggtg
     2041 attgaaaaag tggagacatc caccagggaa ttcacatctt ctactaccgt cccggtcgct
     2101 gccaataatt caaaccagag ttccaaggaa cacgaaaacc ccgttagacc caggaaacgg
     2161 ggattcccac caatcatcgg cgggatcgtt atcggtatcg ggagcgcgag cgcaatagga
     2221 ctatattaca gtatccagga aattaggacc cgataccgtt accttgtggc cgctcttctg
     2281 accggtatca tcctcc
//
LOCUS       DAOOJU010000080         2258 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_37692_length_2258_cov_10.331820, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000080 DAOOJU010000000
VERSION     DAOOJU010000080.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2258)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_37692_length_2258_cov_10.331820"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1496
                     /locus_tag="PK679_09300"
     CDS             <1..1496
                     /locus_tag="PK679_09300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011843841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="methanogenesis marker 14 protein"
                     /protein_id="HPC56185.1"
                     /translation="ARFFDRFLKPRPHIVESPPPPSIAHGPGVYVPEFKIKPYFIVAS
                     VEMGNTTTKCILTGVNLETGMSYVIHKTVRMSRDVRKPKPGEEIFGETLDGTKLTRES
                     VTELVRDTLLQCHEEAHLDIQKDLDFVVRSTGVVAAMDSPDQVGEFVLALANGCLLAG
                     VPPRKMTPPMSKANQAAKLQPFSYADKVVFVGAVAGVIPPVGSTGVEMVANEMEGELA
                     MAGIKEGAKWTPVDFRNPCISIDFGTTLDGRITSDVDPKDPNPFAKTIGNFCGLAGAV
                     PDAIIKGTGLVDPHTGTALDVFGDRSVVSDFALRGQSDVVRSYVDRAHELIDIRLVPP
                     ERKRFGRVPVYADVAKESGVALIGCDAGENGSTLPDLAQLGREIYERHGLGLLNEVID
                     RVCARMALRLVDVANDLGLVLPNSSIGFTGRAAISGRKPEYILEGIIERKLFDNPHDH
                     VVFVDDGLARGAALMGRCMNSLGKPKNPIGGVRGGPCIMARRIKVGK"
     gene            1509..1796
                     /locus_tag="PK679_09305"
     CDS             1509..1796
                     /locus_tag="PK679_09305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56186.1"
                     /translation="MTPEMKDPDRKTDLQEGSGPEEQLFDLLIPPGVPRSIIADIIRK
                     FEVQLVERKQRLYFANMDGDERELLAFRGKKEVVERVQDYLYEELKKFIGE"
     gene            complement(2140..>2258)
                     /locus_tag="PK679_09310"
     CDS             complement(2140..>2258)
                     /locus_tag="PK679_09310"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314948.1"
                     /note="catalyzes the formation of L-citrulline from
                     carbamoyl phosphate and L-ornithine in arginine
                     biosynthesis and degradation; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HPC56187.1"
                     /translation="RGQEVTDDVIEGPRSVVFDEAENRLHAQKALLAFLMRD"
BASE COUNT          520 a          613 c          660 g          465 t
ORIGIN      
        1 gtgcgcgttt ttttgaccga tttttaaaac cgcgtcccca catcgtggaa agtccgcctc
       61 caccgtccat cgcacacgga ccgggcgtgt atgtccccga gttcaagata aaaccatatt
      121 ttatcgtagc atccgtggag atgggaaaca ccacgacaaa gtgtatcctg accggtgtga
      181 acctcgagac agggatgagc tatgtcatcc acaagactgt ccggatgagc agggatgtca
      241 ggaaacccaa gccgggagaa gagatctttg gcgagaccct cgacgggacg aagctcacac
      301 gtgaatcggt gacggaactt gtccgcgata ccctcctcca gtgccacgaa gaggctcatc
      361 tcgacatcca gaaagacctc gatttcgtgg tccggagcac gggagtggtc gctgcaatgg
      421 actcgccgga ccaggtgggc gaatttgttc tcgcccttgc caacggctgc ctgcttgcag
      481 gggtacctcc ccggaagatg actcctccta tgtcgaaggc aaaccaggcg gcgaagcttc
      541 aacccttcag ttatgcagac aaggtcgtct tcgtgggtgc agttgccgga gtcatccccc
      601 cggtcgggag cacgggagtc gagatggtcg caaacgagat ggagggggaa cttgcaatgg
      661 cgggaataaa ggaaggagca aagtggacac ctgtcgattt caggaacccc tgcatatcca
      721 tcgatttcgg gacgaccctt gatggcagga taacaagcga cgtcgacccc aaagatccaa
      781 atcccttcgc aaagaccatc ggtaacttct gcgggctcgc aggggcagtt ccggatgcga
      841 tcatcaaggg taccggtctt gtcgatcccc atacgggtac agccctcgac gtgtttggtg
      901 accggagcgt ggtaagtgat tttgcattga ggggccagag cgacgtcgtc agaagttacg
      961 tcgaccgcgc ccacgaactc atcgacattc gcctggttcc acccgagagg aagcggttcg
     1021 ggagggtgcc ggtctatgcc gacgtggcaa aggaatcggg ggtggccctc atcggttgcg
     1081 atgccggtga gaacggaagc actctcccgg acctcgcaca actggggcgg gagatatacg
     1141 agcggcacgg tcttggcctc ctcaacgagg tcatcgacag ggtatgcgca cgcatggcgc
     1201 tgcggctcgt ggacgttgcg aacgatctcg gtctcgtcct tcccaattcc agtatcgggt
     1261 tcacggggag ggcagcgata tccgggagga aaccggaata catcctcgag gggatcatcg
     1321 agcggaagct ctttgacaat ccccatgatc acgttgtctt tgtggatgac ggccttgccc
     1381 gcggggctgc actcatgggc aggtgcatga attcccttgg aaaaccaaaa aaccccatcg
     1441 gaggagtccg cgggggaccc tgcatcatgg cccgcaggat aaaagtgggc aaatgaggat
     1501 aatgcatcat gacacctgaa atgaaagatc cagacaggaa aactgattta caggaaggta
     1561 gtggcccgga agagcagctc ttcgatctcc tgataccccc cggtgtcccc cgttcgatca
     1621 tcgcggatat catccggaaa ttcgaggtgc aactcgtcga acggaaacag aggctgtatt
     1681 ttgccaacat ggacggggac gagagggaac tgctcgcgtt cagggggaaa aaagaggtgg
     1741 tggagcgggt ccaggactac ctctacgagg aactgaagaa gttcatcggg gagtgacaag
     1801 acttcttccg gaatctttca gtttttttct tttcgttatt tcaaatgggc ggtctgcatt
     1861 agtgctttac agctttttgc agggccgccg gggcgccctt ttgggggcgg gaccatcatc
     1921 acatgggggt atggaaacga ggcagcccct cctttactgc ttcactgctc acctggaata
     1981 gtgaagagcc agttttttcc cggttattca acaggattct ctctccggat acatggggaa
     2041 aaggaatgcc gaaccccggt cagagggcac tccattcccg gtttttctca ccgcctacag
     2101 taatagcccc aaaaatcctg gaaccccttg caatacccct caatcccgca tcaggaacgc
     2161 aaggagagct ttctgggcat ggaggcggtt ctccgcctcg tcgaagacga cactccgggg
     2221 accttcaatc acgtcgtccg tgacttcctg cccccggt
//
LOCUS       DAOOJU010000081         2110 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_41556_length_2110_cov_13.784428, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000081 DAOOJU010000000
VERSION     DAOOJU010000081.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2110)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2110)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2110
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_41556_length_2110_cov_13.784428"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            219..1517
                     /locus_tag="PK679_09315"
     CDS             219..1517
                     /locus_tag="PK679_09315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HPC56188.1"
                     /translation="MITIAKKNPVQPGGLARRLGFWEVTLSGVGIILGAGIYALIGAA
                     AGSAGNAVWLSFGAAALVAFFTALSYMELASMMPAVGAEYEYCARAVGKRVAMVIGWL
                     IIFSGILGAATVSLGFAGYLESLLSVPHLPAAFALLAALTALLLVGVKESALVAVAFT
                     LVEVGGLLLVIIAGIPYLGKVDYLEMPSGIPGVLSAAALVFFAYQGFEEMVKFSEETH
                     RPEKTIPLALIVALGISTALYMLVCVSAVSVTGWQALSSSPAPFAAVASTAWGADASL
                     LISVIALFATANTALMMMFASSRISYGMARAGSLPPALAFVHPERKTPWITSILVGAG
                     ALLFVSAGNIAFVANVSNFTLFVTFIVVNLSVIVLRFREPRARRPFSVPGRVGRFPIA
                     PLLGMVSCALLLLQLEPAVLGLGALVTGAGIVVAVVFGKK"
BASE COUNT          345 a          640 c          687 g          438 t
ORIGIN      
        1 gaacacccgg ttgccgggcg ggaaaccgca gcaccgaaac aaaagcgaaa agaatgttcc
       61 gggaaagaga gcagggatat ggtcacctga ccggaagcag cagatccgct cgtgccgtcg
      121 ccgggaaacg agggtgccag gaaggtggtc gccagacccc ctcctgaaaa aataagacga
      181 aacggggaca acagaactgc atccatcgga atgggggagt gatcaccatc gcgaagaaaa
      241 acccggtgca gccgggcggt cttgcccgcc gcctgggttt ctgggaagtg accctctcgg
      301 gggtgggcat catcctcggc gccgggatat atgccctgat cggggctgct gccgggagtg
      361 cagggaatgc agtctggctc tcgtttgggg ctgcagccct cgttgcgttt ttcacggccc
      421 tttcctacat ggagcttgcg tccatgatgc ctgccgtcgg ggcggaatac gagtactgcg
      481 cccgggcggt cgggaaacgc gtggcgatgg tgatcgggtg gctgatcatc ttttccggta
      541 tcctcggggc agcgacggtg tcgcttgggt tcgccgggta cctggaaagc ctcctttccg
      601 tccctcacct ccctgccgca ttcgcgctcc tcgcggccct gaccgctctc ctcctcgtcg
      661 gggtgaagga gagtgccctc gttgccgttg cgtttaccct cgtcgaggtg gggggactcc
      721 tcctcgtcat catcgcgggc atcccgtacc tcgggaaggt ggactatctt gagatgccat
      781 ccggaatacc gggagtcctc tcggccgcag ccctggtctt ttttgcatac caggggttcg
      841 aggagatggt caagttctcg gaggagacgc atcggccgga aaagacgatc ccccttgccc
      901 ttatcgttgc cctcgggatc tcgacggcac tctacatgct ggtctgcgtc tcggccgtga
      961 gtgttaccgg ctggcaagcc ctctcgtcat caccggcacc ctttgcagcg gtggcgtcca
     1021 ccgcatgggg tgccgatgct tctctcctca tctccgtgat agcgctgttt gcaacggcaa
     1081 acaccgccct catgatgatg tttgcctcct cgcggatctc gtacgggatg gcccgggcag
     1141 gttccctccc gccggccctt gcattcgtcc atcccgaaag aaagacaccc tggataacga
     1201 gcatcctcgt cggggccggt gccctgctct tcgtgtcggc cgggaatatt gcctttgtcg
     1261 caaatgtctc gaacttcacc ctctttgtca cgttcatcgt ggtgaacctc tcggtcattg
     1321 tcctccgttt ccgggagcca cgtgccaggc ggcctttttc cgttccggga agggtggggc
     1381 ggttccccat cgccccgctg cttggaatgg tctcctgtgc cctcctcctg ctccagctcg
     1441 aacctgccgt ccttggcctc ggggctctcg tgaccggggc aggtattgtc gttgccgtcg
     1501 tattcgggaa aaagtgaggc gagtccctat gctggccgga ggggaaagac gcctccggac
     1561 ctccttggag ggggtgccgc agcgaccgag ggttgattgt catcagcgaa ccggagggga
     1621 aggacgcctc cggacctcct catgtgaaga tagggtgcgg gcagggatga tcgggcgtgg
     1681 tgttatgtcc tgttccccag cactagccct atcgccaaac ggggtgccgc agcgaccgag
     1741 gattgtttgt catcagcgaa ccggagggga aggacgcctc cggacctcct catgtgaaga
     1801 tagggtgcgg gcagggttga tcgggctttc tgtcatgtcc ttttccccag cactggccct
     1861 atcgccacac gggggtgccg cagcggcggg gcgtcagccc cgagagcgtc tgaggagggg
     1921 agtgcggtct gtcgtccaat tgcccggagg gggaaacccc ctccggacct cccccttggt
     1981 gaggataggg tgtgggcagg gatgatcggg cactgtgtca tgtcctattc cccagcactg
     2041 gccctatcgc cacacggggg tgccgcagcg gcggggcgtc agccccgaga gcgtctgagg
     2101 aggggagtgc
//
LOCUS       DAOOJU010000082         2067 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_42806_length_2067_cov_3.207256, whole genome shotgun sequence.
ACCESSION   DAOOJU010000082 DAOOJU010000000
VERSION     DAOOJU010000082.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 2067)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2067)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2067
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_42806_length_2067_cov_3.207256"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..273)
                     /locus_tag="PK679_09320"
     CDS             complement(<1..273)
                     /locus_tag="PK679_09320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004039208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HPC56189.1"
                     /translation="MTEAIRTESVTKIFSNNVRALSDVSIRIDQGEFVALVGRSGSGK
                     STLMNILGGLDSPSSGSVFFDNVRVDYKNRKNLINLRRRQVGFIFQM"
     gene            complement(270..983)
                     /locus_tag="PK679_09325"
     CDS             complement(270..983)
                     /locus_tag="PK679_09325"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC56190.1"
                     /translation="MKSRTHLFVLSGFVLAFCMLLLSGAMAASNGTGEHPSGRFVVHC
                     NVDGATVLMDEKEMGTIRNGVLEIDVNTTEPHYRTFTVRSPEKSRLLLWVKEGNDLMF
                     SSYGISPEMATNTIFFDGALPNRKIESAELFLVAPSGGYSRDIVIDINSLMVNQLEEE
                     KTPPLIRTIFSLLFPNYKGKEWSDIFSMDNATQIGFERKEIKPYLKTEENRVAVRDQG
                     DYFQLTNAILAIRYSGDTV"
     gene            complement(980..1651)
                     /locus_tag="PK679_09330"
     CDS             complement(980..1651)
                     /locus_tag="PK679_09330"
                     /inference="COORDINATES: protein motif:HMM:NF023252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3344 domain-containing protein"
                     /protein_id="HPC56191.1"
                     /translation="MVLVTTAGATYAADHPLNTTFFKDLKGDYVFSIGDSTYTSSLYP
                     GQTYSVNFSITIPDDASITFQRLYVYWAWSRILQKAFYPVLSLHDSRDQSHNLTLLSR
                     YSDSKGVVGTYDFYTGMDAYQIPPLHPGKNDFTITIQQDGPPNSSVLFFGMGVLAVYE
                     NRGFETYTGTIDRYPRPGETVDLYASMEVIPVTTTPRASLPGILAILALGCPLLVAIR
                     RRTHP"
     gene            complement(1677..>2067)
                     /locus_tag="PK679_09335"
     CDS             complement(1677..>2067)
                     /locus_tag="PK679_09335"
                     /inference="COORDINATES: protein motif:HMM:NF019325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CARDB domain-containing protein"
                     /protein_id="HPC56192.1"
                     /translation="RNRRPPVYPLLSKILPLVCLALLISAGIGTISVPATADSSTSLY
                     LLPVTVKNSGGSDAPPFSLSVYLDGEKVAMKTFDAGIPSGKEVTADIPVHTTPGTHAL
                     KIIADEEGKVRDSNRGNNIVEKTYVFP"
BASE COUNT          462 a          518 c          585 g          502 t
ORIGIN      
        1 catctggaag ataaacccga cctgccgtct ccggaggttg atgaggttct tccggttttt
       61 gtaatcgaca cgcacgttgt caaagaaaac ggatcccgaa ctcggactgt cgaggccgcc
      121 aaggatgttc atgagggtgc tctttccgct cccgctcctt ccgacgagag caacgaattc
      181 gccctggtca attctgatgg agacatcaga aagggccctg acattgttgg aaaagatttt
      241 tgtcaccgat tctgtcctga ttgcttctgt catacagtat ctcccgaata acgaatggca
      301 agtatcgcat ttgtcagctg gaaatagtcg ccctgatccc tgacggcaac cctgttctcc
      361 tcggtcttca ggtagggttt tatctccttt ctttcgaacc ctatctgcgt ggcgttgtcc
      421 atgctgaaaa tatcactcca ttctttaccc ttgtaattgg gaaaaaggag tgagaatatg
      481 gtccggatga gggggggcgt cttctcttct tcgagctggt tgaccatgag cgagttgata
      541 tcgatcacga tgtcccggga ataacctccc gagggtgcga ccaggaaaag ttctgccgat
      601 tcaattttcc tgttgggtaa cgctccatca aagaaaatgg tatttgtcgc catttctggc
      661 gagatcccgt agctgctgaa catgaggtcg ttgccctcct tgacccagag caacaggcgt
      721 gatttttccg gggatcttac ggtgaaagtc ctgtagtgcg gttccgtcgt attgacgtca
      781 atttcgagca caccgttgcg gattgtaccc atctcctttt cgtccatgag gacggtggct
      841 ccatcgacat tgcaatgaac cacgaacctg ccggaggggt gctccccggt accattcgaa
      901 gccgccatgg cacctgacag gagtaacatg cagaaggcaa gaacgaaccc ggagaggaca
      961 aaaaggtgtg ttctgctctt catgggtgcg tcctcctcct gatggcaaca agcaggggac
     1021 agccaagtgc caggatcgcc aggattcccg gcagcgaagc ccggggagtt gtcgtcaccg
     1081 gtattacctc catcgaggca tagagatcta ccgtctcgcc gggccggggg taccggtcta
     1141 ttgttccggt gtaagtctca aaccccctgt tttcgtagac agccagcacg cccattccaa
     1201 aaaagagcac cgagctgttt ggcgggccgt cctgctgaat tgtgatggta aagtcgtttt
     1261 ttcccgggtg caggggaggg atctggtatg cgtccattcc cgtatagaag tcataggttc
     1321 caacgactcc cttgctgtcg gaataccggc tcaggagagt gagattgtgg gactggtccc
     1381 gggagtcatg cagggatagg acagggtaga aggctttctg gaggatcctg ctccatgccc
     1441 agtatacata gagcctctga aatgtgatgc tggcatcgtc agggatggtg atggaaaaat
     1501 tgacagaata tgtctgcccg ggataaagcg agctcgtata ggtgctgtct cctatcgaga
     1561 agacatagtc ccctttcagg tccttaaaaa aagtggtgtt caatgggtga tccgcggcat
     1621 acgtggcccc ggcagtcgtg acgagcacca tgcataaaag caggaaaaaa atgcggtcag
     1681 gggaagacat atgtcttctc cacgatgttg ttcccgcggt tactgtccct gactttcccc
     1741 tcctcgtccg cgataatttt cagtgcgtgc gttcccgggg tcgtgtggac agggatatca
     1801 gcggttacct cctttccgga gggtatacct gcatcaaagg ttttcattgc aaccttctca
     1861 ccgtcgaggt agaccgagag ggagaatggt ggcgcgtcgc tcccccctga gttcttcact
     1921 gtcacgggca gcaggtagag ggacgtggag gagtccgctg tagcaggaac ggatattgtg
     1981 ccgatgccag cggaaatgag gagcgcaaga cagaccagcg gaagtatttt tgagagcagg
     2041 ggatacacgg gaggtcgacg gttcctt
//
LOCUS       DAOOJU010000083         1807 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_52183_length_1807_cov_14.615868, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000083 DAOOJU010000000
VERSION     DAOOJU010000083.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1807)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1807)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1807
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_52183_length_1807_cov_14.615868"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(97..1134)
                     /locus_tag="PK679_09340"
     CDS             complement(97..1134)
                     /locus_tag="PK679_09340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56193.1"
                     /translation="MKLVEYAAFSGDTLWLLSPTGFSRPCGRLFSLDVRNRRLTELHI
                     PSSGRVERFLVLPGGKILVASSGRELWEYSSGKMKFVSSLPASPLPELWGRYGIGKNS
                     TLRQLWESGMIKGKGNPAGDRIHHMIPYRSGIIILTPASVLRYDLMTDAWNVVCLQHL
                     VPRGLMMSAFFPGDGYCYQGTWNGEDGGDLKRINITTGAVEILYEGTIPVTSLVQDPW
                     HPGTALFSTGMWHTGWNEGGIFRATGDMEPVFSGGAVFSMKSGRESITAATPGGVFRI
                     CRDGSAERYDYPPYESYEGVELVSDPRFGTLVRTHIYQSMMVCGAAAIFPEGEQELSH
                     VLRSLSESNND"
     gene            complement(1407..>1807)
                     /locus_tag="PK679_09345"
     CDS             complement(1407..>1807)
                     /locus_tag="PK679_09345"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HPC56194.1"
                     /translation="YTAWGSWKSPGNPYLKYTWEFLEVFAKGDLKKEGSPDRADISAD
                     EFKKWVVARWSVAPERRMKEYGHPAMFPEELVARALKLFSYEGDVVLDPFAGTGTTCV
                     VARRLNRVYIGIDISEKYCAIAERRLREIL"
BASE COUNT          392 a          556 c          466 g          393 t
ORIGIN      
        1 agggatccag aaatagagag ccccggactt ccgcgaatac gcgtgtaaat tttttcaaaa
       61 gaggcagagc atcttgagct cgggggggag caatcttcaa tcattatttg attcagacag
      121 cgagcgaagc acatgggaaa gttcctgttc tccttcaggg aagatcgcag ccgctccgca
      181 caccatcatc gactggtaaa tatgggtccg gacaagtgtc ccgaatcgcg ggtctgatac
      241 gagttccact ccctcatacg actcataagg ggggtagtca tacctctctg ctgacccgtc
      301 ccgacatatc cgaaatacgc caccaggcgt tgcggcggtg atgctctctc tccctgattt
      361 catgctgaac actgctcctc ctgaaaaaac cggttccatg tctcccgtcg cccgaaagat
      421 cccgccctcg ttccagcccg tatgccacat acccgtgctg aaaagtgcgg tcccgggatg
      481 ccatggatcc tgtacaaggg aggtcaccgg gatagtacct tcatagagga tttcaactgc
      541 tcccgtcgtg atattgattc gcttcagatc acccccatct tcaccattcc atgttccctg
      601 gtagcaatat ccgtcacccg gaaagaatgc ggacatcatg agacccctgg gtacgagatg
      661 ctgcaggcag acgacattcc atgcatcagt catcaggtca tagcgaagga cagaggccgg
      721 ggtgaggatg ataatcccgc tgcgatacgg gatcatgtgg tgaatccgat ccccggcggg
      781 gttacccttc ccttttatca tccccgattc ccacaattga cgaagggttg aattttttcc
      841 gattccatac ctcccccaca actccggcaa gggtgatgcg ggcagggagg agacaaactt
      901 catcttcccc gaagagtatt cccagagttc cctgcctgat gatgcaacca gtattttgcc
      961 gcccggtaag acgagaaacc gctcaacccg tccggacgag ggtatgtgaa gctcggtcag
     1021 tctccggttc cgcacatcga gggagaagag cctcccgcaa ggtcgtgaaa agcctgttgg
     1081 ggaaagcagc cagagtgtgt ctccggagaa ggcagcgtat tcaaccaact tcatgggtgc
     1141 agttcatccc ctgatctgct tccctgcaac atttgctgtc tttgactgaa gaccgatccc
     1201 cgggtgtctt cgtttcagac attgtgcggc gattcccctg ttccggagcc agagaacaga
     1261 ccggaccccc catactctct ttttcctgac cctgctcccg tgcagcgtgc cgcagaaaaa
     1321 ggtggatgaa acgatccacc gttccgggcc ggaaggtgca cacccgcaaa acccccgacg
     1381 acattgctct cctccctttt ccccatttac aaaatctccc gcaaccgccg ttccgcgatc
     1441 gcacagtact tctccgagat gtcgatcccg atgtacacgc ggttcagtct cctggcgacc
     1501 acgcaggtcg tccccgtgcc tgcgaaggga tcgaggacga cgtcgccctc gtagctgaag
     1561 agcttgagtg cccgggcgac gagttcctcc gggaacatgg ccgggtggcc gtactccttc
     1621 atcctccgtt cgggggcaac cgaccagcgg gcgacgaccc acttcttgaa ctcgtcggca
     1681 gaaatatccg ccctgtcagg cgacccctcc tttttgaggt cgcccttggc aaagacctcg
     1741 aggaactccc acgtgtactt gaggtagggg ttgcccgggc tcttccagct cccccaggcg
     1801 gtgtact
//
LOCUS       DAOOJU010000084         1643 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_60239_length_1643_cov_10.986146, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000084 DAOOJU010000000
VERSION     DAOOJU010000084.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1643)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_60239_length_1643_cov_10.986146"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..227
                     /locus_tag="PK679_09350"
     CDS             <1..227
                     /locus_tag="PK679_09350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC56195.1"
                     /translation="LIVSRQDGRIGGISVAGPAGGTIAAYCAFLMKKGVSVHDFSRFT
                     EVHPSSDGVYPLAKYASGRLKREEKARRND"
     gene            423..1040
                     /locus_tag="PK679_09355"
     CDS             423..1040
                     /locus_tag="PK679_09355"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HPC56196.1"
                     /translation="MDREELQAIFEKIQTGVVIIDPKSHTILDINPIAVSLIGRNKEE
                     IVGQVCHQFICPAGRGKCPITDLGQVIDNSERVIIGRDGTRIPILKTATIARVGERDV
                     LIESFIDIRDRKIAEDRRSALIGYISEIVMRVREPLLIVQQNLADLAEKTPKCQGNGD
                     EVRAGLLLEAARIRQIAGNLAEVEKAIAEEREDIPAAYREFLKGQ"
     gene            complement(1123..>1643)
                     /locus_tag="PK679_09360"
     CDS             complement(1123..>1643)
                     /locus_tag="PK679_09360"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HPC56197.1"
                     /translation="GSPVTFGYHLEPILEHVGIAMELDRIPVFRYDGGDTQPVLTLVA
                     EWYSPGRSPLRPGEGVLSVSPASFGLDEKQTVVRSGETVTISSVNLPPGSEVFLKTHG
                     IRTVVLLPVTIHDRTWGLVAFCDKGDRDFSGEEIEAMRIMVNIISGMIGLSLTPVSGV
                     QDSKNRLFSEEK"
BASE COUNT          388 a          473 c          473 g          309 t
ORIGIN      
        1 aattgatcgt ctcccggcag gacggtcgta tagggggaat ctcggttgcc ggaccagccg
       61 gggggactat tgctgcctac tgcgcgttcc tgatgaagaa gggggtctcg gtccatgact
      121 tctcccgctt caccgaagtc cacccgtcga gcgacggggt ctatccgctg gcaaagtatg
      181 cctcaggacg cctgaaacgc gaagagaaag cccggcggaa cgactgaagg gtcagggcaa
      241 aaagacatcc gtctttcccc gggaaacaat cccctgcact tttccgtcct gcacccttcc
      301 gggaaatcca cggcactgtt tttccgggtg attgagtcat accggaaatg cccgccttcc
      361 cggtctgcca atcgcaaacc ctatctcctc tccggttccc atccctgtat cggggacacc
      421 gcatggaccg ggaggaactg caggcaattt ttgagaaaat ccagacaggc gtcgtgatca
      481 tcgatccaaa gagccatacc atactcgata tcaatcccat cgccgtctcc ctcatcgggc
      541 ggaacaagga ggagatcgtc gggcaggtct gtcaccagtt catctgccct gccgggagag
      601 ggaagtgccc catcacagat ctggggcagg taatcgacaa cagcgaaagg gtcatcattg
      661 gcagggacgg cacacgtatc ccgatcctca agactgcgac cattgcccgc gtgggagagc
      721 gggatgtcct catcgagagc ttcatcgaca tccgtgaccg gaaaattgcc gaggaccgca
      781 ggtccgccct gatcggatat atcagcgaga tcgtgatgcg ggtacgcgaa cccctgctca
      841 tcgtgcagca gaaccttgca gacctcgcgg aaaaaacccc aaaatgccag ggaaacggag
      901 acgaggtcag ggcagggctc ctcctcgaag cggcgcggat ccgccagata gcaggaaacc
      961 ttgcagaggt ggagaaggca atagccgagg agagggaaga catcccggcc gcctacaggg
     1021 aattcctgaa agggcagtaa tacaagaaac cgtttgcagg atttaattgc aggagaggat
     1081 cccgcccgaa gggttaaatg cccgcgtgac ctgcgaaaga ttctatttct cctccgagaa
     1141 cagccggttt ttgctgtcct gcacacctga aaccggggta agggagagcc cgatcatccc
     1201 gctgataata ttgaccatga tacgcatcgc ctcgatctct tcacccgaaa agtcccggtc
     1261 ccccttgtcg cagaacgcga ccagccccca tgtcctgtca tggatggtga cgggcaggag
     1321 aacaactgtc cggataccat gtgttttgag aaacacttct gagccggggg gcaggtttac
     1381 cgacgagatg gtcacagttt ccccggacct gacaacagtc tgtttttcgt cgaggccaaa
     1441 ggatgcaggg gaaacagaca gtaccccttc accgggacga agcggggatc ttccggggct
     1501 gtaccactcc gcaacgaggg tcaggacagg ttgggtatcc cctccgtcgt accggaatac
     1561 ggggatgcgg tcaagctcca ttgcgattcc gacatgctcg aggatcggtt cgagatggta
     1621 cccgaaagtc acgggtgatc cgc
//
LOCUS       DAOOJU010000085         1622 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_61458_length_1622_cov_7.192725, whole genome shotgun sequence.
ACCESSION   DAOOJU010000085 DAOOJU010000000
VERSION     DAOOJU010000085.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1622)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_61458_length_1622_cov_7.192725"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..473
                     /locus_tag="PK679_09365"
     CDS             <1..473
                     /locus_tag="PK679_09365"
                     /inference="COORDINATES: protein motif:HMM:NF013736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HPC56198.1"
                     /translation="VGIAMELDRIPVFRYDGWDSSPVLSLVAEWYSPGSSPLRPGEGV
                     VTVPPASFGLYGKQSVVRPGETVTLSSENLSPGSEGVLKTLGIRTVVLLPITIHDRTW
                     GLVAFCDKGDRDFSGEEIEAMRIMVNIISGMIGLSLGPGAGVQGSENKRLPVEK"
     gene            complement(546..1163)
                     /locus_tag="PK679_09370"
     CDS             complement(546..1163)
                     /locus_tag="PK679_09370"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HPC56199.1"
                     /translation="MDREELQAIFEKIQTGVAIIDPSTHTILDINPIAVSLIGRRKDE
                     IVGQVCHQFICPAERGKCPITDLKQVIDNSERVIIAGDGTRIPILKTATRARVGERDV
                     LIESFIDIRDRKVAEDRRCALIGYIGEIVMRIRQPLVIVQQNLADLAEKTLKGQGNND
                     EVRAGLLLEAARIRQIAGNLAEVERAIAEEREDIPAAYREFLKGQ"
     gene            complement(1396..>1622)
                     /locus_tag="PK679_09375"
     CDS             complement(1396..>1622)
                     /locus_tag="PK679_09375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007315093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HPC56200.1"
                     /translation="LIVSRQDGRIGGISVAGPAGGTVAAYCAFLMKRGVSVHDFSRFT
                     EVHPSSDGIHPLAKYATGRLKRTEKNQRND"
BASE COUNT          294 a          464 c          496 g          368 t
ORIGIN      
        1 atgtcggtat tgcaatggag cttgaccgca tccccgtatt ccggtacgat gggtgggaca
       61 gttcacctgt cctgtccctg gttgccgagt ggtacagccc cgggagctcc ccgctgcgtc
      121 ccggggaagg tgtcgtgacc gttccccctg catcgttcgg tctttatgga aaacagtccg
      181 tggtcaggcc cggggaaacc gtgaccttgt catcagaaaa tctgtccccc gggtcagaag
      241 gggttctcaa aacactcggc atccggacgg ttgttctcct gcccatcacc attcatgaca
      301 ggacgtgggg gctggttgcg ttctgtgaca agggagatcg ggacttttcg ggtgaagaga
      361 tcgaggcgat gcgcatcatg gtcaatatca tcagcgggat gatcgggctc tcccttggcc
      421 cgggagcagg tgtgcagggc agcgaaaaca agcggttgcc ggtggagaaa taaaagtatt
      481 cgcagccccg cgggcatcac tccacggacg ctcgcaaaat tttatccggt aaccgagtcc
      541 tcgtattact gccctttcag gaattccctg tatgctgccg ggatatcttc cctctcttcg
      601 gctatcgccc tttccacctc tgcaaggttt cctgctatct ggcggatccg cgccgcttcg
      661 aggaggaggc cggccctcac ctcgtcgttg tttccctgac ctttcaaggt tttttccgcg
      721 aggtctgcaa ggttctgctg cacgatgacg aggggctggc ggatacgcat cacgatctcc
      781 ccgatgtagc cgatcagggc acaccggcgg tcctcggcaa ccttccggtc gcggatgtcg
      841 atgaaactct cgatgaggac atccctctct cccacgcggg cacgggtcgc cgtcttgagg
      901 atcgggatgc gcgtgccgtc cccggcgatg atgaccctct cgctgttgtc gattacctgc
      961 ttcagatccg tgatagggca tttgcccctc tcggccgggc agatgaactg gtggcagacc
     1021 tgcccgacga tctcatcctt tctccggccg atgagggaga cggcgatcgg gttgatgtcg
     1081 aggatcgtgt gggtcgatgg atcgatgatc gcgacgccgg tctggatctt ctcaaaaatt
     1141 gcctgcagtt cttcccggtc catgcccagt ccccggtaca gggatgggaa ccggagagga
     1201 gatagggttt gcgatcggca aaccggggga gtgttcctct ggtatactgt gactatacgg
     1261 gtataccctg gctgtccggg aagaaacccg ccccctgcat tttgcggccg gtggaatgca
     1321 ggaggaaagg ataccggacg gaaaggagca gggtcttttc gcgggggaag atggatgaca
     1381 ttttttcctg cccgtttaat cgttccgctg gtttttttcc gtgcgtttca ggcggcccgt
     1441 ggcatacttt gcgaggggat ggatcccatc gctcgacggg tggacttcgg tgaagcggga
     1501 aaagtcgtgg accgagaccc ccctcttcat caggaacgcg cagtaggcag caaccgtccc
     1561 cccggcgggt ccggcaaccg agattccccc tatacgaccg tcctgccggg agacgatcaa
     1621 tt
//
LOCUS       DAOOJU010000086         1511 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_68363_length_1511_cov_13.889423, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000086 DAOOJU010000000
VERSION     DAOOJU010000086.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1511)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1511)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1511
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_68363_length_1511_cov_13.889423"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            3..107
                     /locus_tag="PK679_09380"
     CDS             3..107
                     /locus_tag="PK679_09380"
                     /inference="COORDINATES: protein motif:HMM:NF013481.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016625 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, iron-sulfur
                     protein as acceptor [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase C-terminal
                     domain-containing protein"
                     /protein_id="HPC56201.1"
                     /translation="MWQRQPLLDEYYELRGWDKNGVPTRQKLEELGLA"
     gene            380..1117
                     /locus_tag="PK679_09385"
     CDS             380..1117
                     /locus_tag="PK679_09385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="HPC56202.1"
                     /translation="MLSLVERERYLRQIPLLGEGGQERLRDAAVLIAGAGGLGSVCAQ
                     MCACAGFGKIRIVDNDVVERHNLNRQVLYAARDHGLFKVDVAARRLRENNPLISVEPV
                     RETITRGSIGNLAKGIDVIIDGMDNYDARYILDDAAFGEGIPLVHGAVNGFYGQVSSV
                     IPGKTPCLHCIVPHPPPSGNIPILGVTVGTVGSIQVAEAIKLVTGLGKPIAGRMLLWD
                     GLMGEAEVIPVSRDPSCTRCNGRGVVP"
     gene            1114..1392
                     /locus_tag="PK679_09390"
     CDS             1114..1392
                     /locus_tag="PK679_09390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD family protein"
                     /protein_id="HPC56203.1"
                     /translation="MKVRVKSFAILRQFLPRETEVEIKEGALVRDLLGLLVKQAPPLA
                     AELFNEQGELKDFVNILLNGRNIHFISGLDSPLREGDLVALFPPAGGG"
BASE COUNT          326 a          417 c          477 g          291 t
ORIGIN      
        1 gggtgtggca gcgccagccc cttcttgacg agtactacga actccgggga tgggacaaaa
       61 acggcgtccc gaccagacag aaactggaag aactgggtct tgcgtgaggt acgtggatgg
      121 tcgcaactcc cggacaggtg catagtccct ggcacgatgg accaaaggaa gagattgtcc
      181 ggcatccggt agtcgaaggg aacaacggga taagttgcgg ctcctgttcc ttcaccggcg
      241 aaaatggagt gtactggttt gaccgggaac ggaaaaaccg ggcaccatct accctgaaaa
      301 ccctgtttgt agcggccagg actgcgcaaa cctctgcccc gacgtaaaag accatggccc
      361 gggtgaaaag gtaaagaaca tgctgtccct tgttgaacgg gagcgctacc tccgccagat
      421 ccccctgctt ggagaagggg gccaggagag gctgagagat gcagcagtgc tcattgccgg
      481 tgccgggggt cttgggtcgg tctgtgccca gatgtgcgcc tgtgcagggt tcgggaagat
      541 ccggatcgtg gacaatgacg tcgtggagcg ccacaacctc aaccgtcagg tcctgtacgc
      601 ggcaagggac catgggctct tcaaggtgga cgtcgccgcc cggcggctcc gggagaacaa
      661 ccccttaatc tcggtcgaac cggtccggga gacgatcaca cgcgggagta ttggcaatct
      721 tgcgaaggga atcgatgtga tcatagacgg aatggacaat tacgatgccc gttacatcct
      781 cgacgatgcc gcgttcgggg agggcatccc cctcgtccac ggagcggtca acggtttcta
      841 tgggcaggtc tcgtctgtca tcccggggaa gactccctgc ctgcattgca tcgtccccca
      901 tccgccacct tccgggaata ttcccatcct cggcgtcaca gtcgggacgg tcgggagcat
      961 ccaggttgca gaggcgatca agctggtgac ggggcttgga aaaccgatcg caggacggat
     1021 gctgctttgg gacgggctca tgggcgaagc ggaagtcata cccgtcagca gggatccttc
     1081 ctgcacccgg tgcaacggga gaggtgttgt cccatgaagg tccgggtgaa gtcttttgcc
     1141 atcctccggc agttcctgcc tcgggaaaca gaggtagaga ttaaagaagg ggctttggtc
     1201 cgggacctcc tcgggctcct cgtgaaacag gccccgcccc ttgccgcgga gctgttcaac
     1261 gaacagggag aactgaaaga cttcgtgaac atcctcctga acgggaggaa catccacttc
     1321 atctccgggc tggattcacc cctccgggag ggcgatctcg ttgccctctt tccccctgca
     1381 ggaggagggt agaataagga aggattcatt gcgatccatc ccccgggttg gccatcacct
     1441 gttcagagtg atagttatgg ttcatgtcag tatcaaaagg gaagactgca cggcgtgcag
     1501 tacctgctgg g
//
LOCUS       DAOOJU010000087         1458 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_72192_length_1458_cov_14.766215, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000087 DAOOJU010000000
VERSION     DAOOJU010000087.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1458)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_72192_length_1458_cov_14.766215"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(103..594)
                     /locus_tag="PK679_09395"
     CDS             complement(103..594)
                     /locus_tag="PK679_09395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013328126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF367 family protein"
                     /protein_id="HPC56204.1"
                     /translation="MIPLLAFRDNSCDPRKCTVRRLERAGLIRVFSQVSRLPRNTLLL
                     DPTAGRALSPADRNPRSLSVLDCSWEVLENIPLGSWRHRRALPFLVAANPVNFGRPWR
                     LSSVEALAAALFIIGERDQAGEILGTVPWGRRFLELNEEPLDLYSKARDSQEVLEVQN
                     LYY"
     gene            625..>1458
                     /locus_tag="PK679_09400"
     CDS             625..>1458
                     /locus_tag="PK679_09400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HPC56205.1"
                     /translation="MYVLMCPCIQDPGLRARGITRESDLRAFEKALRRCRECGLDVVF
                     LPCPETLFLGRDREPGTFLERLNTGDFFHLLDRLERDVKDIIRARGPPLCIVGVNSSP
                     ACGVDTTYYGDDGKGPARRAGRGVFLARFPTIPAVDVTDFCRYRIYLAAPLFSAAERR
                     YNAHLRDILTAHFFSVFLPQEAGDDSSHRDEESQQAIFSRCCREIAESDIVVAVIDGA
                     DADSGTSWEMGYAYARGIPVVALRTDFRRAGMHEHVNLMLEQSSRVVRNEEELLQVLK
                     AP"
BASE COUNT          302 a          393 c          469 g          294 t
ORIGIN      
        1 agtagaaaat accgttcggg aacaaggctt tcgggtatcg ggagagaagg gccggaggca
       61 gcgggggaag atgtaccggg aactgcattt tccgggagaa gatcaatagt agaggttctg
      121 gacctcgagg acttcctggc tgtcgcgtgc ctttgaatag aggtcaaggg gctcttcgtt
      181 caattcgagg aagcgccttc cccacggtac cgtgccaagg atttcccctg cctgatccct
      241 ctccccgatg atgaagagcg cagcagcaag ggcttcgaca gaggagagac gccagggcct
      301 cccgaaattg acggggtttg cggcaacgag aaaggggagg gccctccggt gacgccatga
      361 gccgaggggg atattttcga gaacctccca ggaacagtcg aggacagaga gtgaacgggg
      421 gttcctgtcg gcaggagaga gggcccggcc ggcggtcggg tcgaggagaa gggtattccg
      481 gggcagccgt gacacctggg aaaagacccg gatgagcccg gccctctcga gcctgcggac
      541 cgtgcacttc cgggggtcgc agctgttatc ccggaaggca aggaggggga tcatctatgt
      601 atcattcctc tccattttct atcaatgtac gtgttgatgt gcccctgtat ccaagacccg
      661 ggactgagag ccagggggat aacgcgggaa tccgacctcc gggcttttga gaaggcactc
      721 cgccgctgca gggaatgtgg actggatgtc gttttcctcc cctgtccgga aaccctcttt
      781 ctgggaaggg accgggaacc ggggacgttc ctcgaacgcc tcaacacggg agattttttc
      841 catcttcttg accggcttga aagggatgta aaagatatca tcagggcacg gggaccgccg
      901 ctctgcatcg ttggtgtcaa ctcttctcct gcctgcgggg tggatacaac atactatggc
      961 gatgacggga agggccctgc ccgacgggca ggaaggggcg tcttcctggc aagattccct
     1021 accattccgg cagtcgatgt cactgacttt tgccggtacc gcatctacct tgctgccccc
     1081 ctcttttctg ctgcagagag gcgatacaat gcccacctca gggatattct cactgcacac
     1141 tttttctcgg tcttcctccc ccaggaggca ggcgatgaca gcagccaccg cgacgaggaa
     1201 tcgcagcagg ctattttttc ccggtgctgc agggagatag ccgaaagtga cattgtcgtt
     1261 gccgtcatcg acggggcaga tgcagactcc ggcacgtcat gggagatggg gtatgcttat
     1321 gcccgtggga tcccggtcgt tgcgttaagg acggatttcc ggcgggcagg catgcacgaa
     1381 catgtcaacc tgatgctcga gcagtcgtca cgggtcgtcc ggaacgagga ggagctgctg
     1441 caggtgctca aggcgcca
//
LOCUS       DAOOJU010000088         1231 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_94004_length_1231_cov_12.670918, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000088 DAOOJU010000000
VERSION     DAOOJU010000088.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1231)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_94004_length_1231_cov_12.670918"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..187
                     /locus_tag="PK679_09405"
     CDS             <1..187
                     /locus_tag="PK679_09405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56206.1"
                     /translation="RDMQDRVCHAMLPAIRSSIDIAMEIAVLKTPRRPDTCREIFHIR
                     KPEGRYVLFWITCGSGG"
     gene            430..816
                     /locus_tag="PK679_09410"
     CDS             430..816
                     /locus_tag="PK679_09410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HPC56207.1"
                     /translation="MDLQGEEIIARLSEVPGFSNVRFILLFGSVAEGRAGPGSDVDIA
                     IFYDGDQEEASLFRYKCLIALGSSRYDVTIFQQLPLYIRIRALRGKILYCPDLSFLYD
                     VAYETIRDYDAFKHRLDDYTGEKAIS"
     gene            813..>1231
                     /locus_tag="PK679_09415"
     CDS             813..>1231
                     /locus_tag="PK679_09415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="HPC56208.1"
                     /translation="MTPRPQPSVRKDLIRIKLAEIRDSITVVMRHMPATVDEFLGMGL
                     VKDGIYKKIEYAIENVLDICAVVNADLVLGVPGNDEDILDHLVSHHVISAGVAEKVRG
                     MKAFRNIMVHRYGAINDRTAYRLLVDHLGDFEAFQAE"
BASE COUNT          290 a          340 c          357 g          244 t
ORIGIN      
        1 cagggatatg caggacaggg tatgccatgc gatgctccct gccatccggt cgtcaatcga
       61 cattgcgatg gaaatcgcgg tcctgaagac gccgcgacgg ccggatacct gccgggagat
      121 tttccacatc cggaaacctg aaggcaggta cgtccttttc tggatcacct gcggttcggg
      181 gggataagaa cccgctgaca ttgctgtcct gccttccatc cccaccggga tagaccgatc
      241 gcttcgcaaa gcccgtgcac cggtggcggt ttttgggaaa aatttcgtaa taatgcccgc
      301 atgggggatc aaccagaccg gaacggaaaa aaggccggac agcctcaccc gccccatcaa
      361 aaaagccgaa gagggaaaag agataactat tgtccgataa aaacaagagg ctgagagggg
      421 acggacacga tggacctgca gggggaggag atcattgcac gactatccga agttccgggt
      481 ttctccaacg tccggtttat cctcctcttc gggtcggtgg cagaaggaag ggccgggccg
      541 gggtctgatg tcgatattgc cattttctac gacggggacc aggaggaggc atccctcttt
      601 cgttacaagt gcctgatcgc cctcggcagc tcgcggtatg acgtgaccat ttttcagcaa
      661 ctgcccctgt acatccgcat ccgtgctctc agggggaaga tcctctattg cccggacctc
      721 tccttcctct atgacgttgc gtatgagacg atccgggact acgatgcgtt caagcaccgg
      781 ctggatgact acaccgggga gaaagcaatc tcatgacgcc acgaccgcaa ccatccgtcc
      841 gcaaagacct catccgcatt aaactcgcag aaatcaggga cagtatcacg gtcgtgatgc
      901 gccacatgcc cgcaacagtg gacgagttcc tcgggatggg cctcgtgaaa gatgggattt
      961 ataagaagat tgaatatgcc atcgaaaatg tccttgatat ctgtgcagtg gtgaatgcgg
     1021 acctggtgct cggggtgccg ggcaacgacg aggacatcct ggaccacctc gtgtcccacc
     1081 acgtcatctc ggcgggtgtc gcagagaaag tcaggggcat gaaagcgttc cggaacatca
     1141 tggtccaccg ctacggggca atcaacgacc ggactgcata ccggctcctg gtggatcacc
     1201 tgggggattt cgaggcgttc caggcagaaa t
//
LOCUS       DAOOJU010000089         1203 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_97516_length_1203_cov_5.736934, whole genome shotgun sequence.
ACCESSION   DAOOJU010000089 DAOOJU010000000
VERSION     DAOOJU010000089.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1203)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1203)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1203
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_97516_length_1203_cov_5.736934"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..>1203
                     /locus_tag="PK679_09420"
     CDS             <1..>1203
                     /locus_tag="PK679_09420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HPC56209.1"
                     /translation="LYDPFTCSWTETDIAVSKGWVVGTGDGYGGRTICDLGGKRVIPG
                     LIDAHVHIESSLLVPAEYARVVAAHGTTTVIADPHEIANVCGARGIEYMLNEREGLPV
                     DILFMLPSCVPATPLDTGGATLSAHDLQAFMERRGVIGLGEVMNVPGVLAKDPGVWEK
                     LALFSLRDGHAPLLSGTALNAYICAGLQSDHECTGTDEARAKLVRGMYIFIREGTTEK
                     NLHALLPLASPATAPRLAFATDDRHADILFRDGHIDDCIRKSLEYGLELETALRMATL
                     SPAERFRLDDRGAIAPGRRADFCILEDGKVFSIKKTYSGGRPVLSYPKKNPVPLSSPM
                     EATVPRVKDLAIRGHGTGRVIGIVPGQILTEALSFDVDGERIPDTDRDILKVVVCSRY
                     RKGVTGLG"
BASE COUNT          259 a          356 c          359 g          229 t
ORIGIN      
        1 gcctttatga ccccttcacg tgcagctgga ctgaaaccga cattgcagtc agcaagggat
       61 gggtcgttgg aaccggagac ggatacgggg gaaggacgat ttgcgacctg gggggaaaga
      121 gagtaatccc gggtctcatc gatgcccacg tacatatcga gagctcgctc ctcgtgccgg
      181 ctgaatacgc acgggtagtc gctgcgcatg ggacgaccac cgtgattgca gacccccacg
      241 agattgcaaa tgtctgtggc gcccggggga tcgagtacat gctgaacgag agggaagggc
      301 tcccggtgga tatcctcttc atgctcccct cctgcgtccc tgcaacaccc ctcgacaccg
      361 gtggcgcaac cctttcggcc catgacctcc aggcgttcat ggaaagaaga ggtgtcattg
      421 ggcttgggga agtgatgaac gttcccggtg ttctcgcaaa ggacccggga gtatgggaga
      481 aactcgcgct gttctccctt cgggacggac atgcaccgct tctgtccggg acagcactca
      541 acgcatacat ctgtgccggg ctccagagtg accacgagtg caccggcacg gacgaggcac
      601 gtgccaagct cgtgcgtggc atgtacattt tcatcaggga agggacaacc gaaaaaaacc
      661 tccatgccct cctgcctctc gcgtctcccg ctacagcgcc ccgcctcgcc tttgcaactg
      721 atgaccggca tgccgacata ctcttccggg acggccacat cgatgactgt atccggaagt
      781 cactcgaata cgggctcgaa ctcgagaccg cgctccggat ggcaacactc tctcctgccg
      841 agcggttccg tctcgatgac cgcggggcga ttgcccccgg caggcgggct gatttctgta
      901 tcctggaaga tggaaaggta ttttccataa aaaagacgta ttcgggagga aggccggtct
      961 tatcctatcc gaaaaaaaac ccggttcccc tgtcatcacc catggaggcc actgtccccc
     1021 gggtgaagga tcttgcgata cgcgggcacg ggaccggacg ggtgataggg atcgtgcccg
     1081 gacagatcct cacagaagca ctctcattcg acgtcgacgg ggagagaata cctgataccg
     1141 accgggacat cctgaaggtc gttgtctgca gccgctacag gaaaggggtg accggtttgg
     1201 gcc
//
LOCUS       DAOOJU010000090         1195 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_98542_length_1195_cov_9.519298, whole genome shotgun sequence.
ACCESSION   DAOOJU010000090 DAOOJU010000000
VERSION     DAOOJU010000090.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1195)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_98542_length_1195_cov_9.519298"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..799)
                     /locus_tag="PK679_09425"
     CDS             complement(<1..799)
                     /locus_tag="PK679_09425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56210.1"
                     /translation="MNRFLSPCALVLALVLAGAGCIHAPAGKNDTADARHHVMQQLLQ
                     GVAGSIQQDLDKLDATVSLAAHNLGATGLSGPEADGILRSVVSSHPCIHTAITYDANG
                     TVRAAEPADVKVIIGQNLLDQENVRRATSTQKPLMSEYFALAEGGEAVSITHPVFSSN
                     GEFLGAVSMTFSPSCLVAPYAGEAMGYAPVIVNVAQQDGRILYHPDRALIGKPTFNEP
                     AFASFPGVLALARRYSDERSGYATFSFYRTGTDVVVEKEAFWDTVGLH"
BASE COUNT          241 a          316 c          422 g          216 t
ORIGIN      
        1 cgtggagccc gacggtgtcc cagaacgcct ctttctcaac gaccacgtcc gtgcctgtcc
       61 ggtagaagga gaacgtcgcg tacccggagc gttcgtcaga ataccggcgg gcaagcgcga
      121 ggactcccgg gaacgaggca aaggccggtt cgttgaaggt cggtttcccg ataagggcac
      181 ggtccgggtg gtacaggatc cggccgtcct gctgggcaac gttaacgatc acgggtgcat
      241 accccatggc ctcgccggca tagggtgcga ccaggcagga gggcgaaaac gtcatgctga
      301 cggcgccaag gaactctccg ttcgaagaaa agaccgggtg ggtgatcgag accgcctctc
      361 ccccctcggc gagcgcgaag tattcactca tcaggggctt ttgtgtcgag gtggccctgc
      421 ggacattctc ctggtcaagg aggttctgcc cgatgatcac cttcacgtcc gcgggttcgg
      481 cggcacggac cgtcccgttc gcatcgtagg tgatcgccgt atggatgcac gggtgcgagg
      541 agacgacgct gcggagtatc ccgtcggcct ccgggccgga caggccggtt gccccgagat
      601 tgtgggcggc aagggagacg gttgcgtcga gcttgtcgag atcctgctgg atactgccgg
      661 caactccctg caggagctgc tgcatgacat ggtggcgggc gtctgccgtg tcgttttttc
      721 cggcgggtgc atggatgcac cctgcccctg ccaggacgag tgcaaggacg agtgcacagg
      781 gagagagaaa acggttcatc gggaaaagag gttgacagcg gggatatatg ggatttttga
      841 aacatttttg ccacgggaga gagggtccat cgtcacagga gcacagcacg ggggttgccg
      901 ggagagaaga ggatctgtct tctccggagc accgcatgga gggtttgtcg cgagagagag
      961 ggcccattat ctccgaagca cagtacggtg gttgtcgcag aaaaaaggga tacatcattc
     1021 ccgagctcgg cacgggggtt gtcgcgggag agagtgtcca tcgtcccgga gcatggcacg
     1081 gtgattatcg caggaaagag ggtcgataac cccggagccc ggcacggagg ggttgtcgca
     1141 ggagagagtg tccatcgtcc cggagcatgg cacggtgatt atcgcaggaa agagg
//
LOCUS       DAOOJU010000091         1187 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_99635_length_1187_cov_9.151943, whole genome shotgun sequence.
ACCESSION   DAOOJU010000091 DAOOJU010000000
VERSION     DAOOJU010000091.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1187)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1187)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1187
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_99635_length_1187_cov_9.151943"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..>1187
                     /locus_tag="PK679_09430"
     CDS             <1..>1187
                     /locus_tag="PK679_09430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HPC56211.1"
                     /translation="LYDPFTCSWTETDIAVSNGWVVGTGKGYGGGTIHDLGGKRVIPG
                     LIDAHVHIESSLLVPAEYARVVASHGTTTVIADPHEIANVCGALGIEYMLNEREGLPV
                     DILFMLPSCVPATPLDTGGASLPARDLQEFTGRDGVIGLGEMMNVPGVLEKDPGVWEK
                     LALFSLRDGHAPLLSGRALNAYICAGLQSDHECTGTEEARAKLERGMYIFIREGTTER
                     NLHALLPLASPSTAPRLAFATDDRHADILCRDGHIDDCIRKSLEYGLDLETALRMATL
                     SPAERFRLDDRGAIAPGRRADFCILDDGKVFSIKKTYSRGNLVSIYPKKDPLPLPSPM
                     EATVPRVQDLAIRGHGTGRVIGIVPGQILTEALCLDVEGEKIPDTDRDILKVVVCSRY
                     RKG"
BASE COUNT          254 a          347 c          358 g          228 t
ORIGIN      
        1 gcctttatga ccccttcacg tgcagctgga ctgaaaccga cattgcagtc agcaatggat
       61 gggttgttgg aaccggcaag ggatacgggg gagggacaat tcacgacctg ggggggaaga
      121 gggtaatccc cggtctcatc gatgcccacg tgcacatcga gagctcgctc ctcgttccgg
      181 ctgaatacgc acgggtggtt gcttcgcacg ggacgaccac cgtgatagca gatccccacg
      241 agattgcaaa tgtctgtggt gccctgggga tcgagtacat gctgaacgag agggagggtc
      301 tccccgtgga catcctcttc atgctcccct cctgcgtccc tgcaacaccc ctcgacacgg
      361 gtggcgcaag tctcccggcc cgtgacctgc aggaattcac gggaagagac ggtgtcatcg
      421 ggctggggga aatgatgaac gttcccggtg tcctcgaaaa ggacccggga gtctgggaga
      481 aactcgcgct cttttcccta agagacgggc atgcaccgct gctgtccggt agagcactca
      541 atgcatacat ctgtgccggg ctccagagtg accacgagtg caccggcacg gaggaagcac
      601 gcgccaagct cgagcgtggc atgtacatat tcatcaggga agggacgacc gagagaaacc
      661 tccacgctct ccttcctctc gcgtctccct cgacagcacc ccgccttgcc tttgcaacag
      721 atgacaggca tgccgacatc ctttgccggg acgggcacat cgatgactgt atccggaaat
      781 cactcgaata cgggctcgat ctcgagactg cgctccggat ggcaacactc tctcctgccg
      841 agcggttccg gctcgatgac cgcggggcga ttgctcccgg caggcgggcc gatttctgta
      901 tcctggatga tggaaaggta ttttccataa aaaagactta ttcgagggga aatctggttt
      961 cgatctaccc gaaaaaggac cccctccccc tgccatctcc catggaggcc acggtccccc
     1021 gggtgcagga ccttgcgata cgagggcacg ggaccggacg ggtgataggg atcgtgcccg
     1081 gacagatcct gacggaagca ctctgtcttg atgtcgaggg ggagaaaatc cctgataccg
     1141 atcgggatat cctgaaggtc gttgtctgca gccgctacag gaaaggg
//
LOCUS       DAOOJU010000092         1131 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_107662_length_1131_cov_12.607807, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000092 DAOOJU010000000
VERSION     DAOOJU010000092.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1131)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1131)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1131
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_107662_length_1131_cov_12.607807"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..542)
                     /locus_tag="PK679_09435"
     CDS             complement(<1..542)
                     /locus_tag="PK679_09435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56212.1"
                     /translation="MALVFRSCLVCLLLLLAQGASAVSISLAPDRIQQGDQVTITING
                     LPDGSVFSIMVDGVFAVTPAGSFSFELKNFVLPFTLNEGRFSATLSNTDTNVITVVAG
                     DTEIRKIGRSRNGTFSTSDTGTIPPGTCTLISFGGTAAPDATSVVTRLALAGRKSGPV
                     DSHITFSVDGVTAGAVTITIL"
     gene            611..1030
                     /locus_tag="PK679_09440"
     CDS             611..1030
                     /locus_tag="PK679_09440"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56213.1"
                     /translation="MTAGGLHRFPPGRHRSAEECIHGIPGYSCKDTLIAFARTGKGGT
                     QAVAPLGLVHGGNMPGGLPGRPCRDGTIPFPASRCHAALAPALADGRTTGLSGHGAQV
                     IGLARQRCAGGVIPAGDSGDGREYHRIIHAGKRKVFV"
BASE COUNT          216 a          334 c          371 g          210 t
ORIGIN      
        1 agaatggtga tcgtgacggc cccggccgtc accccgtcga ccgagaacgt gatgtgggaa
       61 tccaccggtc cggatttcct ccctgcaagg gcaaggcggg tcacgacgga cgttgcgtct
      121 ggtgctgcag tccccccgaa agagatgagg gtgcaggtcc ccggggggat ggtcccggtg
      181 tcacttgttg aaaacgtgcc gttccgggaa cgcccgattt tcctgatctc ggtatcacct
      241 gcaaccacgg tgatgacatt cgtgtcggta ttcgaaagag tcgcggagaa cctcccctcg
      301 ttcagggtaa aggggaggac gaagtttttc agctcgaagg agaaggaacc cgccggagtc
      361 acggcaaaca cgccatcgac catgatagag aagacactgc catcgggcag gccgtttatc
      421 gtgatcgtta cctggtcgcc ctgctggatc cggtccgggg caagggagat ggagactgct
      481 gatgccccct gtgcaaggag caggagcagg cagacgagac aggaccggaa tactaatgcc
      541 accctgggat ctccccctta tccgtattct ctgaatggtc cggacacctt tattatcgat
      601 tcggtgacgc ttgaccgccg gagggctgca tcgtttccca cccggccggc acaggtccgc
      661 ggaggaatgc atccatggaa tacccgggta ctcctgcaag gataccctta tcgcgtttgc
      721 ccggaccggg aaagggggga cgcaggcagt cgctcccttg gggctcgtcc acggcgggaa
      781 catgccggga gggttgcccg gtcgcccgtg ccgggatggg acgatcccgt tccctgcatc
      841 ccgctgtcat gcagcccttg cgcctgccct tgccgatgga cgcaccacgg gcctttccgg
      901 tcacggtgca caggtcatcg ggcttgcccg gcagaggtgc gccgggggcg tcatccccgc
      961 cggggacagc ggggacggca gggaatacca caggattatt cacgcgggaa aaaggaaggt
     1021 ctttgtctga cccgggggaa ggatccggaa gatatggagg gggtttctcc tactctgctg
     1081 caggggcact cttcccggca tccgatgccg ccgggtgacc tgcacggtac a
//
LOCUS       DAOOJU010000093         1021 bp    DNA     linear   ENV 10-JUN-2024
DEFINITION  MAG TPA_asm: Methanolinea sp. isolate AMR_MDS_2745
            NODE_127176_length_1021_cov_7.149068, whole genome shotgun
            sequence.
ACCESSION   DAOOJU010000093 DAOOJU010000000
VERSION     DAOOJU010000093.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32864820
            Sequence Read Archive: SRR5007117
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanolinea sp. (wastewater metagenome)
  ORGANISM  Methanolinea sp.
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanoregulaceae; Methanolinea.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1021)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/02/2023 09:44:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.5
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,890
            CDSs (total)                      :: 1,843
            Genes (coding)                    :: 1,838
            CDSs (with protein)               :: 1,838
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 1 (16S, 23S)
            tRNAs                             :: 42
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 5
            CDSs (without protein)            :: 5
            Pseudo Genes (ambiguous residues) :: 0 of 5
            Pseudo Genes (frameshifted)       :: 1 of 5
            Pseudo Genes (incomplete)         :: 4 of 5
            Pseudo Genes (internal stop)      :: 0 of 5
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Methanolinea sp."
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_127176_length_1021_cov_7.149068"
                     /isolate="AMR_MDS_2745"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:2268143"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="34.72 N 135.27 E"
                     /collection_date="2015-05-26"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..183
                     /locus_tag="PK679_09445"
     CDS             <1..183
                     /locus_tag="PK679_09445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HPC56214.1"
                     /translation="GVFTVLGVMPKISGSPPVISLLTEGLKGVVNASFAVEPDPVRAA
                     DLISAHIERKRTELGI"
     gene            216..>1021
                     /locus_tag="PK679_09450"
     CDS             216..>1021
                     /locus_tag="PK679_09450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007313968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HPC56215.1"
                     /translation="MHSSPSGEKVRVVVTGKGGVGKTTLTALLAHSFAREGRTVLAVD
                     GDPQQNLAYTLGLSINEIQSIVSLSERKEYIAEKIGALPGRGGFMVLNPDTADVVDRF
                     SYPAGKGIRLLVMGGVKNAGFGCLCPEFTLLSAVLRNAQCLPGDIVLLDTPAGLEHFG
                     RAVAQGFSTALVVTDTSFNGMVVARELCRLAHECGIPQIVLVTNKVSATGRDVLKNDF
                     SPGYLSGKIEVPEDPCIRTHERSVVSVLDGECPAARAIGRLARVICSWDG"
BASE COUNT          215 a          274 c          307 g          225 t
ORIGIN      
        1 ggagtcttca cggtgctcgg tgtcatgccc aagatctcgg ggagcccgcc ggtcatctcc
       61 ctcctgaccg agggattgaa aggcgtggtc aacgcgtcct ttgctgtcga acctgacccg
      121 gtcagggccg ctgacctgat atctgcacat atcgagagga agaggacaga acttgggatt
      181 tgaggcggga tatgcaacat cccggggagg ggcaggtgca ttcgtctcct agcggggaga
      241 aagtacgggt cgttgtcacg gggaagggag gtgtcggcaa gaccaccctg acggccctcc
      301 ttgcccactc ctttgcacgc gaaggacgga cggtccttgc agtggacgga gacccccagc
      361 agaaccttgc atacactctt ggtctctcga tcaacgagat ccagtcgatt gtttccctct
      421 ccgagaggaa agaatacatc gcagaaaaga tcggggcatt acccggccgg ggtggattca
      481 tggtcctcaa cccggacacg gccgatgtcg tcgatcgttt cagttatccc gcgggaaaag
      541 gaatacgcct cctcgtcatg ggtggggtca aaaatgcggg attcggttgt ctctgtcctg
      601 agtttacgct tctctcggcg gtactgagaa atgcgcagtg tctgcccggg gacatcgtcc
      661 tcctcgatac acccgccggc ctggaacatt tcggacgtgc ggttgcacag ggtttttcaa
      721 ccgccctcgt tgtaaccgat acgtcattca atgggatggt tgttgccagg gaactctgcc
      781 ggcttgcgca cgagtgtggc attccgcaga tagtcctcgt gacgaacaag gtctcggcga
      841 caggcaggga tgtcctgaaa aacgatttct ctcccggata cctttccgga aaaatcgaag
      901 tacctgagga tccctgtatc aggacccatg aacgctctgt cgtttcagta ctggatggag
      961 aatgtcctgc agcaagggcc ataggaagac tcgcacgggt catttgttca tgggatggtg
     1021 a
//
