LOCUS       DAOPZI010000001       157563 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_34_length_157563_cov_9.593862, whole genome shotgun sequence.
ACCESSION   DAOPZI010000001 DAOPZI010000000
VERSION     DAOPZI010000001.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 157563)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 157563)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..157563
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_34_length_157563_cov_9.593862"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..365
                     /locus_tag="PKM11_00005"
     CDS             <1..365
                     /locus_tag="PKM11_00005"
                     /inference="COORDINATES: protein motif:HMM:NF013895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HNX46930.1"
                     /translation="LLHMGIMLPGKVPGKVSYENFAIIYIFALWVFTFVSIATHFVCL
                     ALGLASPGLLVMITLGLVAGLVTVTVLNFLSYYVAVTTFMFSLDPDDHSIPITSSAID
                     FIGSLALMAAIVMFGLSI"
     gene            422..1579
                     /locus_tag="PKM11_00010"
     CDS             422..1579
                     /locus_tag="PKM11_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--phosphoribosylaminoimidazolecarboxamide
                     ligase family protein"
                     /protein_id="HNX46931.1"
                     /translation="MIDRDTILGKLEAYDPEKIKIGVLASHSALDVCDGAVEEGFRTL
                     AVCQEGRDSAYTKYFKAYREKDGRLRRGIVDETLMLKKFKDATSQKVVDRLLKENVLF
                     VPNRSFTSYCGVDSVENDFTVPLVGSRNLLRCEDRGGEKDYYWVLEQAGMPSPRKVKR
                     PEDIDALTIVKLHHKQKKLERGFFTASTPEEYWEKARKLIADGVIEEESLGEARMEEY
                     IIGPVFNLDFFYSPLEEKGSRIELLGIDWRFESSLDGFVRLPAEQQLALNDKQRIPEM
                     TVCGHNSSTMRESLLDGAFELAEKFVRTAEKHFAPGMIGPFCLQTCVDKDLKFFIYDV
                     APRIGGGTNVHMSVGHPYANSLWRQSVSTGRRLAMEVRRAIVQERVAEIVT"
     gene            1733..4627
                     /locus_tag="PKM11_00015"
     CDS             1733..4627
                     /locus_tag="PKM11_00015"
                     /inference="COORDINATES: protein motif:HMM:NF019325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="HNX46932.1"
                     /translation="MQSNKTWKLATGLMVLMLLAMPLLAVMPANVGAATTGNNLSIIV
                     YDENTANPVVGAKVTLIGVHQQNAISPKTTGSDGLAVFTPFDGYYMVTVTHLGYYTYQ
                     SEGVIRFTDLAADTISIPMKMMSADKYTLTVNVNGTTGPLNGASVVVKTVIDNVTTSI
                     SATAVSGVATLQLPNGTYSIVCSNSTYATDVESNVVIAGAAVVKNITLAAAVKYNGLV
                     TLDGAPATGVVAYLVGADPLVETDRKVIKASGTSPFFSFDAFVGNFTLLVDANGALAA
                     VEAVTVAASNPLKNVVLSKQSVQTENNSFAFGASDWNVATLTKTMLLDHDNTVPGLDY
                     AYLPSAKMQIDLVFGNGDGEVNATELAAFGAKMVEFGPIDVTTTDMISVNSKNFISDV
                     ADPGYTITGLLGPVNDTSKFQVEMVAGYTSIEAIANGLAAYTVVVSSQKTLADMSYTY
                     KAALPSLYERVGAATISPAGSGVIVTGYTNLTVTSGTSSATATMKVQKSAAPTAAAAI
                     VTGVNAYKVMNGSTFLYYIVAKGENVTFTASGSSDPNANPLIYRWDFGDGNNSGEISN
                     LTYVHAYANAEQYTVNLTVKSQSGLPAYKSFNVKVDGVNPTVAAKQNVDVLGATLNID
                     QNKAYTFNSAASADMLNATEAGLIHSYKWVWGDGNTTTVLMGENQTVTKTYARSGVFT
                     MYLNVTDVANHTTSKAVTVTVKDTVKPTVKFSVKLNTTVVTSAKEFQNLTFDASASSD
                     ASGIASYLWDFGDGTNSTLASPVHSYSEIKTFTVKLTLTDNAGNVGNTTMGFKVESSA
                     RPDLRVGAVTFDPTKFTEGEDGYIYVNVTNVGTAPAEGIYGKLYKVNSDGTRKLLTDV
                     SVLLVNDTKDTELQVGETGVLRFKVAFDSKGEYTLQINVSANAEVASKMTDNSATKSL
                     TVEEAAWKSYLLYGGIFAVIIVVVVLFLFRKKLPMMSGKKKEVTPPAKKK"
     gene            4666..5400
                     /locus_tag="PKM11_00020"
     CDS             4666..5400
                     /locus_tag="PKM11_00020"
                     /inference="COORDINATES: protein motif:HMM:NF015084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HNX46933.1"
                     /translation="MLRLVDSGLCHPLYSVAIEEALLESCSKGLMPPTLHLYVRDRPT
                     VSLGYFEKVETAIDPQVLLDEDVFLVRRMSGGSTIFTDQGQLIFSLTIDQGAIPNPED
                     AYALTCGVVVNALESLGVKAEHKLPNDILVNGKKISGSAQTRKKGMLMVHGTLLVDTD
                     LDRMMRVLRPKNDKRSRNREQMTCLRDELDRSPDMNQVKDALVQAFSNELEQRAVCIP
                     VNEREKGRVKALIEEKYGKEDFILQF"
     gene            complement(5401..5892)
                     /locus_tag="PKM11_00025"
     CDS             complement(5401..5892)
                     /locus_tag="PKM11_00025"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX46934.1"
                     /translation="MVDIRKLKDEDKPQVRTLELFCIREYLEGSLQKSWDDLPAELME
                     QLGASTKDSFDYYREGGMSYVAVENKQIVGFLFSQIIQYVNNIEKVLWIENLGVHPDH
                     RREGVGLKLLRRAALDGKKKGAKAVQSVVMPDAKDAVMLHKKVGFFIDGRKFAFLDLE
                     NFK"
     gene            complement(5892..7604)
                     /gene="argS"
                     /locus_tag="PKM11_00030"
     CDS             complement(5892..7604)
                     /gene="argS"
                     /locus_tag="PKM11_00030"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: protein motif:HMM:TIGR00456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HNX46935.1"
                     /translation="MDALGHFEKHIISKLSAELSVMGFTGEIVLERPDHEMADLALPC
                     FQFAKQLRKAPPAIAQELGALITTDDKIGKVWADKGYINFRVNETLLSELVIRDAMQR
                     REEFGKGDPRPGRLLLEHTSVNPTGPIHVGRARNPLIGDTLARCLRMCGHDVRTEYYV
                     NDVGKQVVLLTWALAHLTEKDVPPWDRDKNDYRLVGYYQTANKMMESSAEVANDVAVM
                     TQRFEAGDPEVIAQVRRTVDLMLEGIKESLAGIGVFLDRYTYESQFILDGSAREVVDK
                     LKASSYSEIDDGAYYLNLEEFGVHGRDTRFFFTRKDGTTLYTTRDLAYHMDKFKRAEE
                     LMNILGEDQKLGQKQLASALKILGLDRSPECIYYSFVSLPEGRMSTRKGVVVYLDDLL
                     EEAVERAYKEVSTRRPDLDEEKKRSIARDIGVGAVRYNIIRVQAEKQLIFKWEEALNF
                     EGNSAPFVQYSHARCCSILRKTGDFNKSADVSVLTDPSERRLVWILAQFPEVVRQAGD
                     KRRINMLPTYGHELASALNQFYGAVPVLRSEHQDARLCLVEAARWALRNTLVTMGIAA
                     PEEM"
     gene            complement(7605..8852)
                     /gene="prf1"
                     /locus_tag="PKM11_00035"
     CDS             complement(7605..8852)
                     /gene="prf1"
                     /locus_tag="PKM11_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor aRF-1"
                     /protein_id="HNX46936.1"
                     /translation="MDGITGETLSDRQKYDFKRSLEEIRNLKGRGTELISVYVPPTKQ
                     ISDVAAYLREEFSQSSNIKSASTRKNVQGAISSILARLKYFKTPPANGVIFFVGEISA
                     TGDQTRMVQYVLEPPDPITTFLYRCDSDFYLEPLEGMLLDKKVYGLVVIDRSEATVGV
                     LRGKAIHVIRNLDSLVPSKHRMGGQSAQRFERLIEISANEYYKKVSDIMTESFLGIDG
                     LQGILVGGPGPSKEFFIKEGYLHHELAKKVVDTFDIGYTDEYGLKELVEKAKDKLYDL
                     DLMREKRLFQQFLNEIRKSEGGLSVYGEDQIRNAIMIGAVDVLLVSEGIRKRRVTLDC
                     PQCGTLELTIDKSPEGTVMTCPKCGTVGTVTKDVDLVDDLFDQAGMMGTKVELISPDS
                     EEGEMLLKAFGGIAGLLRFSIGG"
     gene            8916..9599
                     /gene="pyrH"
                     /locus_tag="PKM11_00040"
     CDS             8916..9599
                     /gene="pyrH"
                     /locus_tag="PKM11_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HNX46937.1"
                     /translation="MDKIVVSLGGSVIVPDDNDDAFLKRFSEMISSLCDRYQIYLVCG
                     GGKIARYYIKVGRSLGLTEYDLDEMGILSTRINAALVAYSLGDISVGKVPTDILEAHR
                     LEKKGKVVVMGGTVPGHTTDAVSAMLAKEVKAVRIINGTSVDAAYTADPKKDPHAERL
                     SKITHQQLYELVNVGMHGAGPSNVFDRLGAQIARDGHISISIVDGRDIEEMRAAIEGR
                     PIKGTVVSD"
     gene            9706..10347
                     /locus_tag="PKM11_00045"
     CDS             9706..10347
                     /locus_tag="PKM11_00045"
                     /inference="COORDINATES: protein motif:HMM:NF024645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX46938.1"
                     /translation="MPQVQHDAILAGGVFAIIGGILMLVSAFLPWITFEGEPLIFLDL
                     LSLDPVFSVLPAASAVGASLVLLTSVIMVKVFVSRKPLNRLPLYQALISMAGALLVIA
                     TFLLARQEYQGTDALYGAGAFTDVVGAILLMAGSMLIHLMSGHRRKPAATGFKALSER
                     SGQPSGRNEWNPPESSVKAPTCPSCGEELRPGWKACPSCGYALLSDDRERGRL"
     gene            complement(10305..11174)
                     /locus_tag="PKM11_00050"
     CDS             complement(10305..11174)
                     /locus_tag="PKM11_00050"
                     /inference="COORDINATES: protein motif:HMM:NF016312.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HNX46939.1"
                     /translation="MRLLVASLLDPASVNLRDRLLEVAEWSLGGEYQGRPYYRLHNML
                     MVSIERLHLHLDHVDKEVGQALNLEIDEVVFLSKHRAASGKPTLTMHPIGNFGKADYG
                     GKEGSLVPASPAFLSGLLRALSSSAKGLPFEISYEVTHHGPFLDVPTTYVEIGSDETK
                     WDNVEAAQAMAKALLNYVPADGPTVVGIGGGHYAPRFSEVTLVKKVRFGHMVAKHVLD
                     GRTDAEVLEIVGKAINASGTRFAYIHKKSFSRPEARRLNELLVSAGYEVLEGSDLQDL
                     QSLPRSLSSDSSA"
     gene            11305..12561
                     /locus_tag="PKM11_00055"
     CDS             11305..12561
                     /locus_tag="PKM11_00055"
                     /inference="COORDINATES: protein motif:HMM:NF024579.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46940.1"
                     /translation="MATPITVGERIVLHLAQYSKHSNDFDAPFEVSQDGIGEALRISR
                     AHAAIELKKLKEAGTVTERIAHIRAGPVKRKVYFLSEAGETKARNLKDFANRQGIEIS
                     PLLDLKKCKGEDLWVQLNSDSRSLIAKAAVFRKPFKRSALPQTTVSLLPEDKDGMAEL
                     PEPLRESIPALLDKNALREAHSFAADYWLKEGDYVERLHHLMLANRTLEAHMLLSARG
                     WQMARSAGPEMLASLKEMGEVPPRYAKEIRRIKGQAALRNADIKFGRQVAQEMLLTGD
                     PEETTDGLELKGRTLLLEGKAQAALDDLLEVKRTKPSPLLDCDIAQCYGLLGRKDEAL
                     QLMESIGRRGGIDDPDVLEEVYYRKGQVLASIDRSQEAIANFSKALGLARPGDKRAIY
                     KATSSCYEKLGMEDKAREYSRKALKR"
     gene            complement(12551..>12739)
                     /locus_tag="PKM11_00060"
     CDS             complement(12551..>12739)
                     /locus_tag="PKM11_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HNX46941.1"
                     /translation="SWMELGGAGVFRPEVTGPLGIKHPVLAWGLGFERLAMLKWNLKD
                     IRELYVTDLDMLRQSPIF"
     assembly_gap    12740..12839
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<12840..13272)
                     /locus_tag="PKM11_00065"
     CDS             complement(<12840..13272)
                     /locus_tag="PKM11_00065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HNX46942.1"
                     /translation="MNATEVLEGLSHSEKKVLVALQKLEGRASPEKVFEAGDFQQLVE
                     VMNASSWLQSKGAVEIEESARKAYALKDRSLLEKGVPERRALAFIGAKDGSLGVKDLE
                     TAMGKEESSMAIGWLMKKRLARLDKSGAEPMLHLSEEGRNSL"
     gene            complement(13302..13697)
                     /gene="tsaA"
                     /locus_tag="PKM11_00070"
     CDS             complement(13302..13697)
                     /gene="tsaA"
                     /locus_tag="PKM11_00070"
                     /inference="COORDINATES: protein motif:HMM:NF014082.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HNX46943.1"
                     /translation="MSSVEGDVSEIEVFPEFSDGLYRIELLKELDVLFVFDRSEGYDL
                     QVHPRGDPNIPLTGLFGTRSPRRPSPIGLTRVTLLERNGNVLRVSGLDAFVDTPVADI
                     KGVMSKGFSWDPEEMRRMARRKSVRRAHK"
     gene            complement(13712..14833)
                     /locus_tag="PKM11_00075"
     CDS             complement(13712..14833)
                     /locus_tag="PKM11_00075"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HNX46944.1"
                     /translation="MNDDFKVTPWEVTGEIDYDQLITRFGTKKMDQELLDRLAGYGEL
                     HPMLRRGVVYSHRDFDWLLDQYDKGNRFFLYTGRGPSGGTHLGHLMPWMFNRYLQDLF
                     KVNMYFQLTDDEKYLFNENLSLEDTRKAAYENVLDFIALGFEPENTKVILDTKDIKLL
                     YPLALKVAKRVTFSTAKAVFGFENSHNIGSIFYTSIQAAPCFIEDALYGKRTPCLIPC
                     GIDQDAHFRVARDVAPLLGYPKPALIYNKMFPGLTGSDKMSSSQPQTTIFTTDKPKEV
                     KKKIGNAFTGGQVSVEEQRKLGGRPEVCSVFKYQYYLFEKDDKALDDLTERCHKGEIL
                     CGECKQLLTQRINEFLEEHQRKREEARERLHEFLLPDTC"
     gene            complement(14874..15524)
                     /locus_tag="PKM11_00080"
     CDS             complement(14874..15524)
                     /locus_tag="PKM11_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1638 domain-containing protein"
                     /protein_id="HNX46945.1"
                     /translation="MENGKGRLAIIACEILKPELEKLTEGWDDVVHKDYLEFALHIDA
                     EKLKATVQDKVNALEGQVDAVFLGYAVCQSLSGITNHLKVPSVMLEGDDCIAAILGPV
                     EYARQKSLCIGTWFNTPGWALRGIEGAVKELHLDALVDQGYEPKYFLDMLFENYELCV
                     YVDTDVGDAEHYEELSRKFADELGLRHENRPCGTANLSRFLNRARELARTSAERAQ"
     gene            complement(15531..15842)
                     /locus_tag="PKM11_00085"
     CDS             complement(15531..15842)
                     /locus_tag="PKM11_00085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46946.1"
                     /translation="MEFDEYVIDLNADCVCGCMDGDRFHNIYRFPNDYGASVVSSPKN
                     DLKNKGGYRMMLIYYDSPAPEHMWTLDDDNPVGDSIIDCKDWNTVLEYLRRLFALPKR
                     S"
     gene            16088..17530
                     /locus_tag="PKM11_00090"
     CDS             16088..17530
                     /locus_tag="PKM11_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HNX46947.1"
                     /translation="MTLKEGLVEEIASIVGRENCSTSVADLYTYGFDSSIHHHTPDAV
                     VRPGSVEEVSLLVKLASREGIPVVPRGGGTGLCGAAVPIKGGMVMDLTRMNRVKEVRV
                     NDLYCVAEAGVVYDRLNEALSPFKFFFPPTPGSGEACTIGGMVATNASGMRAVKYGAT
                     RDYVLGLEVVLADGSIIHVGTNTIKNSSGYQLERLFVGSEGTLGIITEVTLKIAPRPK
                     KAAMVLAAFDRLEDAGKCVSNIISVPLIPSATELMDDICIRAVNKAVGAGLPDAQAIC
                     MIEVDGEPEMVAKELKVVEEVARRSGASSVQVSDDSKQMAKWTSARKSVMSALSRLGD
                     DLVSVSLADDMAVPISKIPDAVVAFHRIAEENQVIVGTYGHAADGNLHTKMLLDPCSE
                     DSWGRGERAVGQIFDVVISLGGTVTGEHGVGISKAPYMMRERPDAWQTMLTIKKALDP
                     QDILNPGKLMQWEGGIIRDLRYPCRDLCLR"
     gene            complement(17523..18146)
                     /locus_tag="PKM11_00095"
     CDS             complement(17523..18146)
                     /locus_tag="PKM11_00095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent protease"
                     /protein_id="HNX46948.1"
                     /translation="MYDEYGNLVIPRDFGRFHFGRQELVQIAISVAVLTAAFTIVLSG
                     NSPWYFAFGVAAAVSLTGFLLHEMGHKFVAQRYGAWAEYRMYPMGLFMALILSFLGFL
                     FAAPGAVYIQGRISKKQNGLISLAGPSTNILFGTTFIILWLAFPSEGTWSAAFNWIGV
                     LSLFLAGFNLIPLGPLDGKKVLAWSPTAWVLAVIVTAIPLAIGYGLI"
     gene            18241..20160
                     /locus_tag="PKM11_00100"
     CDS             18241..20160
                     /locus_tag="PKM11_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HNX46949.1"
                     /translation="MRNYQHGKVIFRWCDSCGTLVLGEVCGICGRPGREFEVSAPGDI
                     RPCFGKGVDTVADLFQGHFGTSALLRTRSVFLNKVAGEDRTDEVILDGRIVAVIRFEL
                     VKDDFSLELKAEGAALLAKMARKGVIKARRPQGHLKGKKLDGADVLEFSGEFKAGDPV
                     VVVMGNNIAAGEARVDSSQVKEGEKVIHLRSVCKADVPFPLVSADWNDFVKANEKHLR
                     QLESTAVSDIRSFVNNTKLPITLSFSGGKDSLACYGITKKALRKFDLLFVDTGLEFPE
                     TVQYVQSFANAKGERLKIARAGNAFWDNVKAFGPPAKDFRWCCKVCKLGPLTNLIEDN
                     YRDGTVTIEGNRALESFARMDIGFVERNPFVPNQTVLNPIRHWMAIEVWGYIWMEDLE
                     FNPLYEQDFERIGCYLCASCLGSEWKSTGEIHPDLHAQWESKLAEWGKAVGVSPEFVR
                     YGFWRWKSLPPKMRLVAEELQMKVPQMRNDSMELRISKGASPCVAGGFSMEGVLTVPR
                     NRDFSQVAEVLKTVGKVKFSPEFEVVMVKTRDGTLKMFGGGHISAIAPTKEGAQALFR
                     AGAEAFLRGQLCTSCRICERNCKFNAITADGQLKVDDRRCRQCGKCAQACVVAHYYDK
                     LVKAGEGKPAYAGVK"
     gene            20187..20882
                     /locus_tag="PKM11_00105"
     CDS             20187..20882
                     /locus_tag="PKM11_00105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46950.1"
                     /translation="MNWTTMLAAALGVGPALALMFWTLRDYTYPKVERPFFDDRKLFG
                     LLAVGMVIGVVVFVLQSYFNLGYILFALLFAVFEELIKLVILNMPRFARKLDTSFYGL
                     SLGLGIGSTMAFGVVFYTIQQSGELDALGWTTVIILAFQMVLLHASAGAMIGTGSARG
                     EVKGYFAQAGLLHIGFNLLMAIPLNFDNIYLAWVGVILATLLVVYYYAQVHRHLLPAV
                     IKGALKAMERAKA"
     gene            20909..21988
                     /locus_tag="PKM11_00110"
     CDS             20909..21988
                     /locus_tag="PKM11_00110"
                     /inference="COORDINATES: protein motif:HMM:NF013961.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HNX46951.1"
                     /translation="MSEGRRKAGKTLLVVAVVLVVVLLLLLPPTQDLLRKYLLDPFSP
                     QYPEEVQMEIVRTMTLDANGGEITGYTIDLPRPVSVFEDGTYLQRVNSFTVSRAYDHL
                     WDNGTYDTMVWEGDALYDTFTLTITMNVTQRMQVWKLDEESVLDKNEIPEFYRDSYLD
                     DQWRIVVNDPEIEALRDDIVGNETNVYLIAKAIYDWIDENLDYYIWPSTDGPLSSLDT
                     YEKLKGDCDDQSILFCALARSAGVPAWLQLGAVYDPDSGELGGHAWVQMFMPTADGGK
                     NVTIDIVNNRFLVWMPNLFCEFTDNGKAEDLQKAYYTTSIFFDPSTYGPTEGPVREDS
                     WTVVSYQESERTVALNLILIAREDF"
     gene            complement(21985..22386)
                     /locus_tag="PKM11_00115"
     CDS             complement(21985..22386)
                     /locus_tag="PKM11_00115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46952.1"
                     /translation="MFGAVVCPRCRKGFAVDLEHRSSTCPHCGRTVQTRRMKTHFTSN
                     SASLTAQAVAELNTKGREPKGFQGKLVLKKRTPPFKPSSLEDLATELKDFDLDDLEKA
                     LDGRMNAEEALRRLVSSGFVYECGPGRYRMA"
     gene            complement(22386..22856)
                     /locus_tag="PKM11_00120"
     CDS             complement(22386..22856)
                     /locus_tag="PKM11_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvoyl-dependent arginine decarboxylase"
                     /protein_id="HNX46953.1"
                     /translation="MNLVPKKFFVTQGSAVSKVSDLNAFDEALMKAKIGEQNLVSVSS
                     VLPIGAKKVAARELPMGAITHCVLAQMRGGEGEMISAGIAYAQRKDGKGGYVAEGHMH
                     GTKKALKEVLEWKMTEMSALRGIELLRINYAIEELSIPMDHYGTCLGALVFVEY"
     gene            complement(22897..23847)
                     /locus_tag="PKM11_00125"
     CDS             complement(22897..23847)
                     /locus_tag="PKM11_00125"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX46954.1"
                     /translation="MGKDMRPFFVMPGSALGDLREELQLLNGNDAGRTMERYGFRAGV
                     GLVRTLGLECADIQDAKAIIEQVWMETGLSRMNIEMINETEIVITFKESVEADNGDHC
                     DFTRGYLSGIISSLMRRRYDAYEASCISDGAVKCVHVLTPSTTYPTEKGVALNKDESG
                     RKYLLEPGTSYLVESSSLDAAYQMYKDQVAEGCTGMVLAREYPEKVQKTYGIGDGALL
                     WLSYERGKRYAREPTDIPMIYSEIKNFFEANSRAVVLLSGLEYLISQNNFLKVLKLLQ
                     LLNDNVSTTSSMLIIPVVPEALNPQDVKMLERELRVLEIG"
     gene            complement(23849..24355)
                     /locus_tag="PKM11_00130"
     CDS             complement(23849..24355)
                     /locus_tag="PKM11_00130"
                     /inference="COORDINATES: protein motif:HMM:NF012300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rab family GTPase"
                     /protein_id="HNX46955.1"
                     /translation="MAKRQFVKKICLLGDGEVGKTSLIRRYVLDQFDDQYIQTFGAKV
                     SKKVLELEDVNLTLMIWDVLGQKTKKELHNTYYLGANGVLLVCDMTRPETLEHLENWA
                     ADLFEVSGKIPILILGNKCDLEMTIDLQDLKAFADKLGCKFMLTSARTGQNVQEAFQA
                     LGELTMEV"
     gene            24484..24987
                     /locus_tag="PKM11_00135"
     CDS             24484..24987
                     /locus_tag="PKM11_00135"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX46956.1"
                     /translation="MPKTEMRFEDVLVDDVFDKFVLKPSQVGKGATIAMVIDQMLANP
                     LSRKVYVTDAENRYIGTVSTETVLRLMGYRLGVREYGGASFIRFLKDTLKERADDIMV
                     KGRTVTRETKLTAAMKIMIDDHLNDLPVVDNEGRLVGELASLQLLMAGKKVFEAKDPA
                     VPPVNEY"
     gene            complement(24989..25753)
                     /locus_tag="PKM11_00140"
     CDS             complement(24989..25753)
                     /locus_tag="PKM11_00140"
                     /inference="COORDINATES: protein motif:HMM:NF021287.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAC2 family protein"
                     /protein_id="HNX46957.1"
                     /translation="MPISDGEIFIHEYDEVDLKDGMVVVGFPSVGLVSSIASNYIVRT
                     MKLERRAAIISKHFPPFTIIHEGVPSPPVRIYAGQRDCVKGEMCEKLAVITCEFMPQP
                     DLIKELSDDILGWCKKKGIATILTLEGINMVGESDTKVYGVGTTERTREMLKTYGIKE
                     LKEGMVTGISGLLLSEGERYQMDVICLLGSARTDVPDARGAANLLDVIGDMLPEIKLD
                     PEPLIKEAELIESEMQKAMESVQQPKKPVEYSQLYG"
     gene            25844..27118
                     /locus_tag="PKM11_00145"
     CDS             25844..27118
                     /locus_tag="PKM11_00145"
                     /inference="COORDINATES: protein motif:HMM:NF017044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HNX46958.1"
                     /translation="MESGLGLHRTAAGIPVIVEEVPHSRTAALSVNFSVGCRDEDKES
                     SGTAHFLEHIMFKGTRKRNARQFSELVEGAGGEMNAYTTKESTSFHVFSLDETFDVMK
                     GLMADMMTAPLMDEEHVDLERGVVMQEISMLEDDPEDYSRVLLDRSIWDGHPMSNTET
                     GRPEWVSSLKAADLRKFFEDHYRPPNLCVVACGHVSAEDVVSWAERTFDGLSHAKSQK
                     VRTPPVPKAYTRVFPKEGDQAYVELGFPGLPGKHLDRKALTLACIILGGGTSSRLYQT
                     VREDQGLVYHISTFPQSYTDCGIVDTFFSASIDNLDRVVNTLAKEISLFKDQGPTEEE
                     VQRSKRWIKGMLVRRLEGTDSRLYWQGEHYMMNGELADAERSIAEFEKVNREDVTRVI
                     NEIFQRKKMCVAMLAPQKEGEAAARRMQSLDF"
     gene            complement(27115..27576)
                     /locus_tag="PKM11_00150"
     CDS             complement(27115..27576)
                     /locus_tag="PKM11_00150"
                     /inference="COORDINATES: protein motif:HMM:TIGR00072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation protease"
                     /protein_id="HNX46959.1"
                     /translation="MKASRLLLGIGSPIVCDDGVGFRIVEEIKNRNLPDLDVDQQSVS
                     GLDIIEIMMDYQKVVVVDAIITEKYPAGTVMLLEPEDFKTALHGTNPHETNIHMAIEV
                     GKLLFPGRMPEDIRFVAVEVNDVYTVTDIMTEDVEKAVPAAVEAVLKVLND"
     gene            27666..28466
                     /locus_tag="PKM11_00155"
     CDS             27666..28466
                     /locus_tag="PKM11_00155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HNX46960.1"
                     /translation="MSLVQASLTVQVNGHVLTDKQAKAVLALYLKGTQRAAARSLGIS
                     APVLCRHLRQVEVKASAPIMDCGPRGTVLNELGESIAKEQLALQSKLRERQQLAVACT
                     PLTEELMMQALNVADPKGDIEVVISDDTHNVTDFQAGLLDLVLLDDPLFAYEAEGASW
                     EEVGSDRLLHVRKGEDYASYRFGPQRLGFRSLEAQKVPHRVVRTYSSLGALVRSGHSY
                     FVSEGLLVRKGYRPKGDEPAIPYAILCLYRPVPKVDGILRAIRNKPVN"
     gene            28554..29063
                     /gene="hdrC"
                     /locus_tag="PKM11_00160"
     CDS             28554..29063
                     /gene="hdrC"
                     /locus_tag="PKM11_00160"
                     /EC_number="1.8.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase subunit C"
                     /protein_id="HNX46961.1"
                     /translation="MSNVKIPDPAFTQSIIDAGGKTLDLCYQCGTCTGSCPSGRTTAF
                     RTRQLIRKAQLGLKDDILPSEELWMCTTCYSCVERCPRDVDIVDIIILMRNMAVQKGY
                     MAEDHKKVGRSLINSGHTVPASDKLKHLRVSMGLSENPPTTIADPKALADFKKIMAKT
                     GFDKLIGGA"
     gene            29065..29919
                     /gene="hdrB"
                     /locus_tag="PKM11_00165"
     CDS             29065..29919
                     /gene="hdrB"
                     /locus_tag="PKM11_00165"
                     /EC_number="1.8.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase subunit B"
                     /protein_id="HNX46962.1"
                     /translation="MAADKFALFLGCVAPLRYPGIEKATRELFKALGYDLREMTGAGC
                     CPAPGVIRSFDQATWLALAARNLAIAEKQDCDILTICNGCYGSLYEANHMLQEDPELL
                     RKVNVILSEVGMKYEGKVRVRHFADVLFKDIGIEKMKQKFTKPLTYNVAVHYGCHFSR
                     PTKIKHIDDPERPHVLDELVEWTGAKSIPYADKQMCCGAGGGVRSRDAKFALSFTEAK
                     LKNMKAVKAQFIIDVCPFCHLQFDRGQKDLPGYDIPVIHLAQLYGLALGLPVSSLGLE
                     AHEIKVTL"
     gene            29929..30213
                     /locus_tag="PKM11_00170"
     CDS             29929..30213
                     /locus_tag="PKM11_00170"
                     /inference="COORDINATES: protein motif:HMM:NF017208.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF749 family protein"
                     /protein_id="HNX46963.1"
                     /translation="MEQAHLVGVYTQEEMPEELEGFVRYQAVCDGHQMKAGERIAVLN
                     VTGTSSYVPVFMADLKGYDDLESRLSKHGVQADQVSALSLRRVLQEMGHS"
     gene            30331..31047
                     /locus_tag="PKM11_00175"
     CDS             30331..31047
                     /locus_tag="PKM11_00175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3ae"
                     /protein_id="HNX46964.1"
                     /translation="MAATKKASTKAASRKVKDRWKAKEWYKIYAPRMFNQAQLGETPS
                     ADATNLIGRTTEATVHDINGDFSKMHVKLKFKVQDVNGFDAHTVFIGQDLTSDYIRRL
                     TRRKRTKTDHVIDVRTKDGYLIRVKPMSITEKRIQSSQETALRTLMDAEMAKMGEEKT
                     ISEIIKAIIDGEMAHRLGSVCKVIVPIKRVEIRKTEVLEMGAGPQDQPVFAPEAPAEP
                     EAVAEAPAEEAIVAPAEAEQ"
     gene            31063..31166
                     /locus_tag="PKM11_00180"
     tRNA            join(31063..31100,31131..31166)
                     /locus_tag="PKM11_00180"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31097..31099,aa:Met,seq:cat)
     gene            31237..32418
                     /locus_tag="PKM11_00185"
     CDS             31237..32418
                     /locus_tag="PKM11_00185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsA family ATPase"
                     /protein_id="HNX46965.1"
                     /translation="MHLFGERTRVIIYTGKGGVGKTSVSAATALRCAKMGYRTIAIST
                     DSAHSLADSLDIPLSGEIRKIGKNLDAIEVDVIHEMENRWQEIGKYLSDFMVSQGLDP
                     ITSKEMTVWPGMELMSALFYIEEFQKSGVYDVVVMDTAPTAETLRLLSFPDTADWYFD
                     KMYKIFRNTVRLARATVGKVMSMPMPTDAFLNDLDHLKDRLKSVRQILLDSETTSVRL
                     VLNPEKMVINETKRAYTYLSLYNLTVECIVVNRLLPEEARQHYPEVKYEEQSRYMQVI
                     EESFSPLKMLKAYQSPTEVIGKRSLEALANQLFGDTDPAQVYSTEKSMEIYNRDGVDQ
                     LSLKLPFSSKDQVELYKSNDVLIVTVGWYKRSVALPYSLVKKEAHKAEFKDGRLVISF
                     K"
     gene            32428..32730
                     /locus_tag="PKM11_00190"
     CDS             32428..32730
                     /locus_tag="PKM11_00190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46966.1"
                     /translation="MASKKEGTEEKKQETPSPSFSSGPMPQDAMVHLLKSGTEFLAAI
                     DTLMPRSIMPPEAKVHYNNIRKETLLMFRSFIDSQLSDIDKKKEAPAPRLRKIDLD"
     gene            complement(32732..33289)
                     /locus_tag="PKM11_00195"
     CDS             complement(32732..33289)
                     /locus_tag="PKM11_00195"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX46967.1"
                     /translation="MRSKEVREILVREVMSSRPRTGRPDMTVKEAAALMLRESVGSLI
                     ILEEGQPVGILTERDLLYKVVAVGKVPSRTKVEKVMSSPVITITPGSNVSIAAKRMSE
                     LHMRRLPVVEDGKLIGMLTEKDILKLSPSLIELTREWSKIGAIPGARANGFGKLAGYC
                     ESCDAYSIALELENGSLLCPDCREE"
     gene            33415..34008
                     /locus_tag="PKM11_00200"
     CDS             33415..34008
                     /locus_tag="PKM11_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00296 family protein"
                     /protein_id="HNX46968.1"
                     /translation="MKDQEGGMAVKLARRAIDAETRDLDVDRFDVPDGFRRMSGAFVT
                     LKTFPGDELRGCIGYPEPVFPLAEAILRAAQGACHDPRFPTLRPEELDQVVVEVSVLT
                     PPMELKVDDRREVPKAIVIGRDGLIMERGMYRGLLLPQVPVEWEWDVTTFLEQSCLKA
                     GLPPDMWLDRKTRIFTFQAEIFHEESPYGQILRERTQ"
     gene            34013..35263
                     /gene="pyrC"
                     /locus_tag="PKM11_00205"
     CDS             34013..35263
                     /gene="pyrC"
                     /locus_tag="PKM11_00205"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: protein motif:HMM:TIGR00857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HNX46969.1"
                     /translation="MDVVEGKLFYQGRLQKACVGIEDGRIVSVRKVLRGDEHFDFGDR
                     LVLPGAVDPHVHFRDPGLTGKEDFSSGSLSALYGGVTCVLDMPNTVPPVIDASSLKEK
                     REAVSGRSWIDYGLMAGIAPRTDVASLGKCIAYKIFLGSSTQSVLLKEEKDLARALDE
                     VGRAGRPVSVHAEEDAMLLRMDERSLRDHEECRPRQAELAAIERLKRYHERARINVCH
                     VSCSDSLSSLKGSGMTFEVAPHHMLLDSSMDLGVWGKVNPPLRRRADREALFQAFCRG
                     EVPMLATDHAPHTAAEKERGFGEAPSGLPGVETGFAMMLALVKKGFLSMDVLLNAACS
                     NPATTFGLNKGQIAEGRDADLVVIDPREVTIIKGRNMHSKCDWTPYEGREALFPQAVF
                     LRGTLVLKDGSTMAERKGREISYA"
     gene            35256..36386
                     /locus_tag="PKM11_00210"
     CDS             35256..36386
                     /locus_tag="PKM11_00210"
                     /inference="COORDINATES: protein motif:HMM:NF015639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HNX46970.1"
                     /translation="MLNGPLPLDLSELEGRKFVCQDPCKLCCLCQPECLPEEVDFFKK
                     NYPNRLVLKKEPHKHYALALKKGQGSCSFLQGGRCEVYPHRPHFCRQFPFHIHVGSRA
                     QIELDLSCRGVWLGQGEDAMTEGLRMVQEKETEIRRTLKESVPVYREFTLNCQEAGLE
                     IDVSKVRAQVAARLDELTDLRLIASLLEESVEEDELSIPGLKAKPLLDAKTMGELSHS
                     ALEMVTDSMAADELFQAPVYCAPDGSWNLFRVLGQKVEWHVLGVEGDVTKRGELPIKD
                     IKLQQPEGRDRQVLRDYLKILNDRDSFMGYAFYLMDDYDYEDPWPNVYGGVLSTSILD
                     LLWRTSLIAAFFPGMKDGERMREGIIFYDMDRLDAPTLGAFI"
     gene            36466..36681
                     /locus_tag="PKM11_00215"
     CDS             36466..36681
                     /locus_tag="PKM11_00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177702.1"
                     /note="Enables 3` processing of polyadenylated mRNAs and
                     tRNA precursors; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small nuclear ribonucleoprotein"
                     /protein_id="HNX46971.1"
                     /translation="MQKPLNVLNQAINNQVIVTLKGNREYRGVLDGYDPHMNLVLKNA
                     EELINSEVVRKLTVTIVRGDNVIYISP"
     gene            36692..36859
                     /locus_tag="PKM11_00220"
     CDS             36692..36859
                     /locus_tag="PKM11_00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L37e"
                     /protein_id="HNX46972.1"
                     /translation="MTKGTASHGKMGDKKTHVPCRRCGRRAYNIRASFCASCGYGKTA
                     TMRTYNWAKTH"
     gene            36877..38283
                     /gene="purF"
                     /locus_tag="PKM11_00225"
     CDS             36877..38283
                     /gene="purF"
                     /locus_tag="PKM11_00225"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HNX46973.1"
                     /translation="MEDDRPKHFCGIVGMALEGDVVPHLKKSLRIIQHRGQEAAGIAV
                     FNGKTMSYHRGMGLVHEVLVGRQYNALVGNTGIGHVRYSTSGSSCAENCQPITVTTKE
                     GDLALAHNGDIVNAASIRTKLQAEGWAFLTSTDSEIIVRIMATELSISPDPIRAIKTV
                     MKTLEGAYSIVMMIGGRTFGFRDPYGFRPLCLGKLSNGYVLASESSVFDVLRGEFIRD
                     ILPGEIVEITPTGVTSTRTPAAPHKAHCMFEWVYFARPDAVIDGQEVYRVRTSIGHIL
                     AKEQPVDADVVVPVPDSGRAHALGYAEGSGIPYAEGFMKNRYIERTFILPDQAQRDEG
                     VLLKLNPIRSTVAGKKVVIVDDSIVRGTTMLKIVQMTRRAGAKEVHVRIGCPPVIAPC
                     FYGVDMKTREQFAALNRTPQQIAELITADSVGYISQAGLVEALRIPESELCLACVNGE
                     YPTRIVGEKMRFQKTLEV"
     gene            38343..38735
                     /locus_tag="PKM11_00230"
     CDS             38343..38735
                     /locus_tag="PKM11_00230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46974.1"
                     /translation="MGNKVRRNRPLGVTIIGVLLFIFGLFMILGGITLGALTDLEGLD
                     LAIEMVALAMGVIYILAAFGFFKGWGFVWLLTMIVVVIGIIWNILSWVLGGLDMDKVA
                     SLLIGLIIPIIILLYMNSSNVKTFFRRG"
     gene            38832..38904
                     /locus_tag="PKM11_00235"
     tRNA            38832..38904
                     /locus_tag="PKM11_00235"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38865..38867,aa:Ala,seq:ggc)
     gene            39037..40029
                     /locus_tag="PKM11_00240"
     CDS             39037..40029
                     /locus_tag="PKM11_00240"
                     /inference="COORDINATES: protein motif:HMM:NF024989.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HNX46975.1"
                     /translation="MKAIVWTRYGPPEVLEYRDVSKPVICKGEVLIRVYATSAFTGDC
                     ELRRFQVPSSLWLFTRLYLGLTRPKRVTILGQEMSGMVEAVGQGVSNFAAGDMVFGLT
                     GMRFGTYAEYVCVPNGALMVEKTDGLTFEEAAVLSVGGLEALHFIERAKIREGQRVLI
                     NGGGGSIGTLALQLAKDAGAKVTCVDSQIKLDMLKDLGADQVLDYTKDDILGNAEGYD
                     VILDLVGKTPVPELVRALKDHGLLVMGNSGPFAPKLFGLWASMSGGKRVVSNQSSGTI
                     EELERLRDLVTSGKIRLVIDRSFPLERTADAHRYIEQGLKKGNVVINVAGGKGS"
     gene            complement(40047..40715)
                     /locus_tag="PKM11_00245"
     CDS             complement(40047..40715)
                     /locus_tag="PKM11_00245"
                     /inference="COORDINATES: protein motif:HMM:NF016831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX46976.1"
                     /translation="MRKLILDMVPSPSTKEEMRPLFEKIHSYEILESLRIDLEECTCI
                     DLVEFILKDDIEIAERTNIGDMEILSVLRSEGRKRVCLIKHHEPEERKDEFREFDLDL
                     IYTAPTKISEDRMVVSVLAEQKELRRFLELVKPTAERITSMSFMRAAYQKQDVLSVLT
                     DRQRETVMTAYQHGYYDYPKKISSEELSKKLGISKGTLMEHLRKAEGRILREILTGYS
                     PKEP"
     gene            40826..41632
                     /locus_tag="PKM11_00250"
     CDS             40826..41632
                     /locus_tag="PKM11_00250"
                     /inference="COORDINATES: protein motif:HMM:NF025687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4386 domain-containing protein"
                     /protein_id="HNX46977.1"
                     /translation="MYSERVWKKRTDRSVSGQADQDGPGARTAWPTKRLALTAGLLYL
                     GVIIFGIFAQMARMDLIVPEDAGATVANILGSSGSLQLALVSDIAMCSCFILLGVVSY
                     VMFKKTHDCVAWIMLLLVVVSGAYAFYNLHNVIEAIQIVNGAGQLTVDEQEMVLALLN
                     AHEDGTYIANVIGWGPWLVPLGYLGYRSGFVPKAIGFILIAGGIGLTAQSLQYFLLPD
                     LGDLFAPGVVLSIIGEFAICAWFIYSGVRGNRFSSGIDERTKEIDPVDPR"
     gene            complement(41899..42813)
                     /locus_tag="PKM11_00255"
     CDS             complement(41899..42813)
                     /locus_tag="PKM11_00255"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HNX46978.1"
                     /translation="MKTPTPDYKEHILQSIGNTPLVRINKLNPNPNVTILAKIEGFNP
                     TGSIKDRIALAMVEQAEQEGKLTKGKTIIEPTSGNTGVALAMIGAIKGYGVEIVMCAA
                     VSVERRQMIKAFGGTVTLSPATDGTDGAIRLAKKLVAENPDKYFMPDQFSNKYNKIAH
                     YKTTGDEIWKQTGGKVDYLVSALGTSGTIMGVGRALKEHNPNVKIVSAHPVKGHYIQG
                     LKNMEEAIVPAIYDPSKIDITIMVETEDAYEMTRQIVKQEGIFVGMSSGAAMYAAAEI
                     AKRIDSGTIVTLFADRGEKYLSTNLFSC"
     gene            complement(42917..43240)
                     /locus_tag="PKM11_00260"
     CDS             complement(42917..43240)
                     /locus_tag="PKM11_00260"
                     /inference="COORDINATES: protein motif:HMM:NF025178.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="HNX46979.1"
                     /translation="MPTKKVALLSEMPPGTMKGVEIDGRHILLANVDGVIYGMDGLCS
                     HMAARLWEGSLDGHVVKCPKHGSRYDVRTGEVVSQVRIPLIGKAKPLGIYKISIEGGD
                     VLIDI"
     gene            43468..44358
                     /locus_tag="PKM11_00265"
     CDS             43468..44358
                     /locus_tag="PKM11_00265"
                     /inference="COORDINATES: protein motif:HMM:NF016777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HNX46980.1"
                     /translation="MIIDSHVHLWLRDHLPDAMVRMYLEPLIALEGLMDWDVQTETVW
                     PEYTVGPDKILEAMDDGGVDKAVILPIDFNLVEKARLDVNEYNTWVFETCATAADRLI
                     PFIGVDPQRGDQALDVLDRYVKRYDARGVKLYPSTGWYPNEERVRRFLDRVDELGLVI
                     VTHAGAAWGSLDERFSEPSFWNEVLHRHPDTNIVLAHLGGRWRQQAYQMCKEYPNCFT
                     DCSALQGWLPSDPETAISRLKELAATIPDKVSFGSDFPLFELSYTTPMWAHFVRTQPW
                     ADEDTRAKLLGGNMRKVLGI"
     gene            44401..45291
                     /locus_tag="PKM11_00270"
     CDS             44401..45291
                     /locus_tag="PKM11_00270"
                     /inference="COORDINATES: protein motif:HMM:NF016777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HNX46981.1"
                     /translation="MIIDGHVHMWLRPMYPDVIINAYLEPWLAMSEFLDMTEEIEKSF
                     PTSEVRPDLLVEFMKQGGVDRSVVLPLDFGLVQEPKVGVEEFNDWIFESAAIYPDKLI
                     PFMGIDPGRGEQAIRLMRKYFAKFEPKGIKIYPPNGFYPYEERLKPFWKEVSDMGLVV
                     VSHAGASWGPLDEEKSRPIHFRSVLDKYPDLRLIIAHLGGKYRADTYELAKEYDNLYT
                     DCSALQGWLPAEPQMVKDRLTEAFSVMGDRVIFGTDWPLFDLSYPYESWCSLVRELDI
                     CSEGRREKLLGGTMQKLLGI"
     gene            complement(45292..45858)
                     /locus_tag="PKM11_00275"
     CDS             complement(45292..45858)
                     /locus_tag="PKM11_00275"
                     /inference="COORDINATES: protein motif:HMM:NF013077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HNX46982.1"
                     /translation="MDVKEAVDKRRATRAFDAKPVSDGLISELVDAMRLSPSCNNNQP
                     WRIIVARDPSSLEAIRSSLPRGNGWATKAPLIFVVCSRLDDDCKLTDRRDYHLFSTGL
                     AVGEMMLRATEMGLIAHPIAGYDPVAIKEKLGIPADQVLITLIICGYPGSDVSMLSEK
                     QLLAEVERPPRKPVGENFFDGSWGNPWA"
     gene            46010..46110
                     /locus_tag="PKM11_00280"
     tRNA            join(46010..46047,46072..46110)
                     /locus_tag="PKM11_00280"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46044..46046,aa:Arg,seq:tct)
     gene            complement(46154..46993)
                     /locus_tag="PKM11_00285"
     CDS             complement(46154..46993)
                     /locus_tag="PKM11_00285"
                     /inference="COORDINATES: protein motif:HMM:NF015648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HNX46983.1"
                     /translation="MGKNKGGSLLSRAASGSPASDYLISGENIKWQGKPAAIIIMGKG
                     LLLTAFALVYLVLMEFLYNSNEDLLVLVIAVAACLLMIITDRKRLGLIGGLAGIAIIT
                     WTALIDKQLPWYWYLIPLVFALLLLAINYIYLSRVLFVVTDQRIITRYGIFTLRYADT
                     GIEKVQSVTTIQPWYERILGYGDVFFATAGEKGGIDYESPGIKLMSGGAVSWENVGKP
                     FEVTKIASAVIHMDVTPVSIVNQPSKMSAAEKLDKIEDLRKRGIISQEEYEKERKEAL
                     EEL"
     gene            47399..47570
                     /locus_tag="PKM11_00290"
     tRNA            join(47399..47436,47536..47570)
                     /locus_tag="PKM11_00290"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47433..47435,aa:Trp,seq:cca)
     gene            47744..48349
                     /locus_tag="PKM11_00295"
     CDS             47744..48349
                     /locus_tag="PKM11_00295"
                     /EC_number="2.1.1.100"
                     /inference="COORDINATES: protein motif:HMM:NF040696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004671 - protein C-terminal
                     S-isoprenylcysteine carboxyl O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-S-isoprenylcysteine O-methyltransferase"
                     /protein_id="HNX46984.1"
                     /translation="MALIQRLRLLLNITIFAFIYVICAAAALFIRVIFMLMIGDRKAY
                     RSSFTDKLLVFLIVASMIAPLAYILTPHLNFANYHVPDAMAWSGAVLIVASLLLLWRS
                     HADLGVNFALTPGVHGEQSLVRKGVYRRVRHPMYTSLWLWAFSMPLLLHNLVAGAIFI
                     AVFGSFYFARVPIEENHMTERFGDKYKEYMGETGRLFPRFK"
     gene            complement(48705..49808)
                     /locus_tag="PKM11_00300"
     CDS             complement(48705..49808)
                     /locus_tag="PKM11_00300"
                     /inference="COORDINATES: protein motif:HMM:NF025022.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HNX46985.1"
                     /translation="MEVDKEFITVVLNESRMADKGNLIVRSDLLDLDLLALDLDHQQV
                     QWVVRERDYDEAYGRMRSALGDQMARDIPTFLDLREALQASLFMPPTNLDALMAEIYR
                     FNERRGDPYRFPRQTCIGLDTNLLYRRLFSRLLLAGKGCNVRSFDPQRVQVLIPSMAE
                     EELSRRVGKKYDRRDVDELRRAVRDRIVADDLFNCLNKNGRKALNGQAEVVALKQHYN
                     CWSAQGGSFVDDKEARDDEMLRSVAAEMLEQRVDVLFLTNDDKTRAHANAHKVPSMLI
                     SYPYEVPLTISYDPWLMIELLYDLSILHTSLSLKGTGIRIKGEWMGKTVDDYRNEKVR
                     VTVPDGSVLSDRLARDQRVISAIKSRFPWKEIK"
     gene            complement(49808..50281)
                     /locus_tag="PKM11_00305"
     CDS             complement(49808..50281)
                     /locus_tag="PKM11_00305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46986.1"
                     /translation="MGKVLLTMMGRSFWGLFNSVWSNIRQFDYLPDKVYVLTAGCEAA
                     QGQMARDMLIVLLKEHGSPADVELVDVPGDDIKQIGQTVNDIVAAEKGKGNIVAVDVT
                     PGTKATVLGTIIGAGKVKVNHIFYLYIESLQNASRPYLEIPLELQSSHDLLKEVR"
     gene            complement(50384..51001)
                     /locus_tag="PKM11_00310"
     CDS             complement(50384..51001)
                     /locus_tag="PKM11_00310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46987.1"
                     /translation="MKHMLRTVLAIVMAFAMLGAFCLSAPTTSAAGKVADVVITEKID
                     VAFDIERGDLDALLEMIPPEDLERIAEEHPCLLRLVEEWDDEVITVALDGMVHVNLKT
                     WEKKDSLDVKLQAFWHGDITIFIDGEQVLALEIKNLQIMAHVIIYDGGIGSAIINAHV
                     NGEISSLPLDFNLDLKAHLLLHYVNGQMHFKLWLPEFLEMPVCEA"
     gene            complement(51076..52011)
                     /locus_tag="PKM11_00315"
     CDS             complement(51076..52011)
                     /locus_tag="PKM11_00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46988.1"
                     /translation="MSYPVKLISYEEKDALYEKYSSFPFHTAKADISGCCVKLYTLND
                     HIKDMWEDNFYSMSETVRSHGRVICLDDPGRPLEVLFEPNTKTAFLFNFDYYGWIKSV
                     ALALAGDILEDEHQIHSVHGAALDINGKGITLIAPSKTGKTTHSWGLLRDKNARLVTD
                     DWYFVRLSERRPVAYGSEKNCYIDADIGSIWDEYRELVKKAKFDNRQRAVVNVRWVTG
                     KGSVVPLTTIHEVVMLKRDKSDARLVRELTSEEAWEYLSANDLCNPHQMVRDERKMKL
                     RETFFRKFLSQSRVHLVNTTATPQETQAAIRRILG"
     gene            complement(52027..53616)
                     /gene="cimA"
                     /locus_tag="PKM11_00320"
     CDS             complement(52027..53616)
                     /gene="cimA"
                     /locus_tag="PKM11_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citramalate synthase"
                     /protein_id="HNX46989.1"
                     /translation="MPARASIFDTTLRDGAQTEGVSFSTEDKLKILERLDAFGIDFIE
                     GGYPASNPKDKAFFKAAQKVKLKNGKLVAFGATHRPGVRPEEDKGMEALVETKTEWVS
                     VFGKSWDLHVEKALQVSLDDNLRIVHDTVAFLRKKGRHVIFDAEHFFDGYRDNPDYAM
                     KVLHEAEDAGAEWICLCDTNGGAFPSLVGKVVSQVRQEMKVPIGVHAHNDGELAVGNS
                     LAAVEAGASMVQGTINGLGERCGNANLCSVIPNLMLKMKVETGVKNLDQLSKLSNFVA
                     EMANVSPDPRAPYVGKSAFAHKGGIHVSAVLKDSRTYEHVEPELVGNLRRILVSELSG
                     VSNIMAKAGEMGIDTEKDGGRSILELMKRREAEGFHYEAAEASLELLIRKLKGENTSP
                     FRLDGFRTFMDVTGDVMTSEASVRVVDSDGTMEHTAADGNGPVNALDRALRKALERFY
                     PVLKEVRLIDYKVRVIDGKDATAAKVRVLITSTDGNQTWTTIGVSGNIIEASLMALID
                     SIEYKLMRAGVNGNGVSLNCQ"
     gene            complement(53691..54713)
                     /locus_tag="PKM11_00325"
     CDS             complement(53691..54713)
                     /locus_tag="PKM11_00325"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HNX46990.1"
                     /translation="MRLALVGFGTVGQGVAEAVAMKKDFVFDRFGTDLKIVAAFDSMT
                     YAMDPKGLKPLELVSKKQSGKGLGKTRPKSVAEMLRELDYDVLVEMTPTNIENAEPGY
                     TNIRTALECGHDVVTSNKGPLALKYRTLDDLSKKNGVELRFEATVGGATPIINLSREL
                     LMAEKVESMKGILNGTCNFILSRMGEEGLPFEYVLKEAQEMGYAETDPSYDIDGIDSA
                     SKLAILANAIMGLDVTYHDVRRTGIRRITQEAVELATKEKKVIRLIGEVNGGGVEVSP
                     RMVPMGHPLSISGTLNVLHMHTDLAGAITVTGRGAGRKETASAIMSDLVSLLKRNTCL
                     SNGKVK"
     gene            complement(54715..55212)
                     /locus_tag="PKM11_00330"
     CDS             complement(54715..55212)
                     /locus_tag="PKM11_00330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46991.1"
                     /translation="MRVNVDLRLKDVPGQLIKALEPISINEGNIVGVVHNHDLVTGGR
                     ISVNVTFEHKDQRSLEAIFSAWKERGVEVVKMGEIVRTYPAEYLMVGNLAHSTLRAIT
                     EGIEKMEGVETIDLQYSLSTSTANKSVLLLVSLRNKEKIKDIDDYLMTRSKRNDFLLV
                     RGMGV"
     gene            complement(55333..55433)
                     /locus_tag="PKM11_00335"
     tRNA            complement(join(55333..55381,55396..55433))
                     /locus_tag="PKM11_00335"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55397..55399),aa:Ser,seq:gga)
     gene            complement(55484..56266)
                     /locus_tag="PKM11_00340"
     CDS             complement(55484..56266)
                     /locus_tag="PKM11_00340"
                     /inference="COORDINATES: protein motif:HMM:NF012993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HNX46992.1"
                     /translation="MRLALCQLRSAVGDKERNLQRMVETVEGTDADLFVFPETYVTGY
                     MVRDRFITLAEDIDGDSVNFVLDLADRTGKAVVFGMPLNDPCVHGLITNSAVMVTSDG
                     RVQRYDKLHPANFGPFEEGLYFTPGQSPAMFSFRGRGVGVCICYDLFFPEICKAYAMQ
                     GADLLLCIAASPVTSRMPFEKIIPARAVENTCPIAYVNNVGNQQNMVYFGGSQAYDAR
                     GRLLAKLPYLRESVDVVDVDMLQTEPARRARPTIRDSLGGLR"
     gene            56346..57143
                     /locus_tag="PKM11_00345"
     CDS             56346..57143
                     /locus_tag="PKM11_00345"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: protein motif:HMM:NF010587.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD+ synthase"
                     /protein_id="HNX46993.1"
                     /translation="MPQLKELTVETIQEFIQTQFKESGASGVVVGLSGGIDSAVVTKL
                     CVDAIGADKVLNVFLPSPSTPKQDLQDVQDMSKAWGTTLLVYDIGQLLKAYHKIMPGS
                     DGKEVSGNLMARIRMTILYAHANLDWRLVMGTGNKSELLMGYFTKYGDGGADLLPIGD
                     LYKTEVRELARAIGIPERIIDKEPSAGLWEGQTDESEMGIAYDDLDLVLSGLEDQQSL
                     DFISRKTGVPMALVEMVASKNAMSRHKRRLALIPKLGNRTIGCDWRE"
     gene            complement(57144..57623)
                     /locus_tag="PKM11_00350"
     CDS             complement(57144..57623)
                     /locus_tag="PKM11_00350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46994.1"
                     /translation="MQFEHDRRPAFVNLVLWAIMAMWLMIILAFLPHERLLFVVVMGA
                     LLVITVLVIGVSPLLTMHEVIDGKIVLRQGWHSKVVIPLDQVKRLQRLERIEVKEGVL
                     LDAFNRTLVMTDSKVNGIRLEMKSVVRVPAAFWKRVDVVIFDVSDPDRFVAEVTRSL"
     gene            57719..57796
                     /locus_tag="PKM11_00355"
     tRNA            57719..57796
                     /locus_tag="PKM11_00355"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:57755..57757,aa:Glu,seq:ctc)
     gene            complement(57911..58786)
                     /locus_tag="PKM11_00360"
     CDS             complement(57911..58786)
                     /locus_tag="PKM11_00360"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HNX46995.1"
                     /translation="MDKGPVLLVLVAGTLFGLCVPFSKVLIGDIEPVMMAGLLYAGAT
                     VFTGTLFVLRRRTSLRPKPSKLARSDVLNLMGSTLFGAIIAPILLMVGLKWTAGSDAS
                     LLLNLEGVMTAVIAVAFFHDKGGYRLWLALAAMTIASTVLSYTPGGGFGGSGAILIVL
                     SMLCWGIDNNLMQKISHLDPVKLSTIRSGIAATFSLTLAFILYGGQDLVVAMVFAMII
                     GAISYGFSNVLFFFGLRHLGASRTGTLFSVGPYAAAMAAIPLLGESVTAKLVIAGLLM
                     AAGTLLLIKERPADD"
     gene            complement(58931..59263)
                     /locus_tag="PKM11_00365"
     CDS             complement(58931..59263)
                     /locus_tag="PKM11_00365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46996.1"
                     /translation="MTSKVRYHMFPCDNRSNIEVSMTDDGDFEVKVTSTCPKVERFVN
                     GLNPLSMTDLTDKTESKVFREFVISDMSANCLTPSAVLTAAWVEAGMIARSNTKKGIP
                     LSIEFVND"
     gene            59808..61322
                     /locus_tag="PKM11_00370"
     CDS             59808..61322
                     /locus_tag="PKM11_00370"
                     /inference="COORDINATES: protein motif:HMM:NF023425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ice-binding family protein"
                     /protein_id="HNX46997.1"
                     /translation="MVLTAVPAAGLGNGANGSINNSLAMANAESQASVDLGSAGNFVA
                     LAKSGISTTGSTNIVGDIGVSPIDSTAITGFGLIMDSSNEFATSSLITGKVYASDYAQ
                     PTPSIMTTAIGDMETAYTNAAGRTSPDHTELGAGDIGGMTLAPGLYKWSSNLLIPADV
                     TLEGCSSAVWIFQIAQDLLISEGKQVMLSGGAQADNVFWQVGGQTTLSTTSVLYGNVL
                     CHTAIVLNTGATLNGRALAQTAISLDANAVTVPESASEPRVISTIPANAATGFSINSR
                     ISATFNMAMDASTITTSTFLVMQGATSVTGNVTYNGVTAVFEPISDLAISTVYNVTIT
                     TSVEDSSGNALISNHTWSFTTGTTADVTAPTVTLTVPINVATEVAVDGTVTATFSEGV
                     DPSTVSTTTFTVKKGTMAVEGTVTYSGLKAIFTPSEDIEYSTNYTATISTGVEDLAGN
                     AMVSAHTWRFTTVDAPEEDGSTEFPLWAMALIILVAAGVIGVVVYRVVKKPSKK"
     gene            61469..61798
                     /locus_tag="PKM11_00375"
     CDS             61469..61798
                     /locus_tag="PKM11_00375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX46998.1"
                     /translation="MVEVITIAGFLVAWLVSTLVIYFVTKLFGQTEDIGKAIMAALIG
                     TVIYALAYFLFGNGLLAALVAGIVWLLALRSLYKIDWGKALIIAIIVWIVALVIGFFL
                     PTLSGPF"
     gene            complement(61868..62629)
                     /locus_tag="PKM11_00380"
     CDS             complement(61868..62629)
                     /locus_tag="PKM11_00380"
                     /inference="COORDINATES: protein motif:HMM:NF012760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016742 - hydroxymethyl-, formyl- and
                     related transferase activity [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formyltransferase family protein"
                     /protein_id="HNX46999.1"
                     /translation="MKRIGWFTTGRGPGSLGLFSTVRSMIKSKEIDAELSFVFMNREV
                     KGNQHRAKLIAMAEEDGIPVIILPSDGFRNDLKGKDLNAWREAYGKAMRDKISEHPMD
                     FGVLAGYMLILDPETCLKHEIINLHPALPNTYQGTWEEIVHRVAESDDATYGSMVHVC
                     TPELDRGDTVAYDQFDISDLREDIGSRDDLAKAIRAREVKREVPLLVETVKMLVSGEV
                     AIRNGRLFDRFGKKMNEAPCLATVIDEWPNQKVSR"
     gene            complement(62661..63074)
                     /locus_tag="PKM11_00385"
     CDS             complement(62661..63074)
                     /locus_tag="PKM11_00385"
                     /inference="COORDINATES: protein motif:HMM:NF016211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HNX47000.1"
                     /translation="MKEECESGSKLVRWSLIVAGTLCLSLGLVGIFIPVLPTTPLLLL
                     AAACYARGSQRFYCWLINNRLLGSYIRSYREGQGLPIKVRAFTIAMLWLTMGLTTVLF
                     IEDDWLRVLLLVIAVAVTVHVASLRPKERSDPGRE"
     gene            complement(63097..63903)
                     /locus_tag="PKM11_00390"
     CDS             complement(63097..63903)
                     /locus_tag="PKM11_00390"
                     /inference="COORDINATES: protein motif:HMM:NF013245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47001.1"
                     /translation="MSENVSNPLRVFWSSAVLAKRALFAWLNPAMWIMQLFGMSLFQI
                     AFFVYVAKFVNNSEVSMEFVAIGNALQSLAYVSVFAVCNITGEEKNQGTIENLLVSPA
                     NRFSVFVGRAAFQIVNGLATVTIAFLYAALIFNVDFSQANYLGLATVILVTTFAMTGF
                     GLMLSSLGLFLRTSMIVANIFLFIGLLLCGVNFPVSFLPGYLQPFSYAIPMTYGTEAA
                     RMAVQGASLGELSGLLGMEALVGFIVMIAGYLMFRGFEYLARSKGTLDRF"
     gene            complement(63905..64693)
                     /locus_tag="PKM11_00395"
     CDS             complement(63905..64693)
                     /locus_tag="PKM11_00395"
                     /inference="COORDINATES: protein motif:HMM:NF013245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47002.1"
                     /translation="MPRLRATAASFRHQAAMFWAEPQWIIPNIIAPFVLAMVVLMLYQ
                     EPSPEAVLYAVLGGGMMGMWGNTLYASGFSIQSDRWWGTVDAIFSAPSPLIWIIGGRT
                     IWNALVGIVNGLFVLVAAMVIFQTPLEVADFWLFMLAFVLTLLSLATLGMLFSAAFVL
                     TRSAQVLTNGLEFPIYVGTGSMFPIFLLPYWSHPLSYSLAPTWGIDAIRYAALPAYAD
                     GFSVGYWGDILYLAILSVLYLTVSIWLYKAVDHRARKTANLMRY"
     gene            complement(64686..65669)
                     /locus_tag="PKM11_00400"
     CDS             complement(64686..65669)
                     /locus_tag="PKM11_00400"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47003.1"
                     /translation="MDSDEIVIDVKGLVRKYHSTTGILHQKKKETVAVNDIDFQVRRG
                     ELFGLLGPNGAGKTTTIKVLTTLLLPTSGSVKILGYDVVKESMEVRKRIGLILGGERG
                     LYYRVTARQNLRYFADIYGVPISIRDKRIEEVLKRVNLLDKADTRVEDYSRGMKQRLH
                     IAKGIIHDPELIFMDELTIGLDPEAARDARDMTKDLVAEGKTILLTTHYMYEADELCD
                     RIGVITRGKIVALDTPSKLKSLVKDTSVIEVEGFGITEKDLDLLKALDGVRTVTANMS
                     EDKQTMRVQVCDPVSLLPKVTHLLEDRKVIGMKVKEPTLEDAYLWLVREDA"
     gene            complement(65838..66218)
                     /locus_tag="PKM11_00405"
     CDS             complement(65838..66218)
                     /locus_tag="PKM11_00405"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47004.1"
                     /translation="MYGGSSDRREMPKLHQVEETAEQRPKPPQVPLPAIILASVGGMI
                     LFMGLFFLLVAGLGVDGFLVPALVVIAVAVLMMLSAWFIWRKTRVSHEDRLRKNEERL
                     LCDYCGGMNAEGDLRCRFCGAPLR"
     gene            66347..66628
                     /locus_tag="PKM11_00410"
     CDS             66347..66628
                     /locus_tag="PKM11_00410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin family protein"
                     /protein_id="HNX47005.1"
                     /translation="MMSKIPVELGALKADHLDREILRTAMIAELDAVSLYEQLAAMTA
                     DHKIRRILLDVAREEKTHVGEFQVLLLLIDPEQSEELEEGRKEVEEELG"
     gene            complement(66659..67195)
                     /locus_tag="PKM11_00415"
     CDS             complement(66659..67195)
                     /locus_tag="PKM11_00415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HNX47006.1"
                     /translation="MSLWKNLPSGRNPPEIVNVIIETPKDSKNKYEVSKEFDCMLLDR
                     VLHSSVVFPLAYGLIPRTFYEDGDPLDAMVLISEPTFPGCVVEARPVGVLEMSDEKGQ
                     DDKILTVACGDPRNNQYLELEDIPQHLLDEISEFFKTYKRLEEKKGTNVIGWQGRARA
                     TEIVSDSLTLFRNKFGYK"
     gene            67370..68638
                     /locus_tag="PKM11_00420"
     CDS             67370..68638
                     /locus_tag="PKM11_00420"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX47007.1"
                     /translation="MGEDYIQTVLFQLFIIILMVEVARMICNRVKIPTVIGEILVGII
                     IANTFLYNFINLGSDREVFEVLKELGVIFLLFTVGLETPFSSIRKVGKTAMFVATFGV
                     IIPFFVGYVFMILTLGPEKQLESMFVGAAMVATSVGITARVIKDMNLMQAVESRVIIG
                     AAVIDDVMGMIVLAVVVGIASGGSLDIIQVAAVSIQAVLFVLAIIFIGSLLLPKMVKQ
                     RDEKKAKQVCTADRKRKGFGPLPLALIVCFALSSMSAFLGLAAIIGAFLAGMAFGEFK
                     DKWPCEEKIEPITEFLTPFFFVFVGIEVSLAAFGEFEVLLLAVAITVLAIITKFIGCG
                     LGAKSLGGKSAAIIGVGMIPRGEVGLIVASIGFAMKDPITGLNIIEPGLYNAIVFMSL
                     FTTLLAPPLLTYTFRRKLGKKCEMVPPDIE"
     gene            complement(68675..68842)
                     /locus_tag="PKM11_00425"
     CDS             complement(68675..68842)
                     /locus_tag="PKM11_00425"
                     /inference="COORDINATES: protein motif:HMM:NF002318.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit Sec61beta"
                     /protein_id="HNX47008.1"
                     /translation="MAKDNKTGGFQSAAGLIRYFDNEDEKALKLSPYLVIALCVITIA
                     VVVVASSLFPT"
     gene            68965..70497
                     /gene="lysS"
                     /locus_tag="PKM11_00430"
     CDS             68965..70497
                     /gene="lysS"
                     /locus_tag="PKM11_00430"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0017101 - aminoacyl-tRNA synthetase
                     multienzyme complex [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HNX47009.1"
                     /translation="MHWADVIANTLIERGGKHLISTGITPSGSIHVGSLRESITANAV
                     YKALKDKGADVDFIYLVDSYDPLRKRYPFLPECFEKEVGKPICYIPCPDGCHASYAEH
                     YITPFLNAIGELGIKPRIIWTHKLYEEGKFTEIVDLVLRERSKVGQILGEVTGRKMPE
                     NFWPFSAECPKCGMFSDKISGYDFPYVHFKCHCGYEGDADIRKGEGKMPWRVEWPAKW
                     KLFGVTCEPFGKDHAAAGGSYDSGVRLCREIYGVEPPHPVPYEFIQFKGKGQMHKSTG
                     NVVTGTDALLITPAPVLAFSVLRYNPERHIDYDPGMGILDIVDEFDKVEAYYFNGGAD
                     EKEKDLLRAYEIAQPSAVRSKLPLQVPYRHLVSVAQVSDSFESAVKVLRRSMDLPDIS
                     TEDMEVLDQRLNCVRHWLNAFAPEEVLYTVSQERPDVEITDEERAYISVLRERLAETE
                     WVGELVHNAIFNTAKELGMQPKVCFLALYRLFINRRSGPRLGFFLSTLDRDFVLKRLS
                     EA"
     gene            complement(70506..70865)
                     /locus_tag="PKM11_00435"
     CDS             complement(70506..70865)
                     /locus_tag="PKM11_00435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47010.1"
                     /translation="MNDRASVTLTSLTASYLIIATAAAILIAWIVRDWTLFIPSMLLL
                     GGMFATFVGFKQRSGALERRRSNDGNFLMFWGTLLVAFGAIWAINYAYPGNVLFLVIG
                     FLVWLGIAVILFTLKKR"
     gene            complement(70915..71202)
                     /locus_tag="PKM11_00440"
     CDS             complement(70915..71202)
                     /locus_tag="PKM11_00440"
                     /inference="COORDINATES: protein motif:HMM:NF022420.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2769 domain-containing protein"
                     /protein_id="HNX47011.1"
                     /translation="MDRFESEIRRLDALRPEELERWIEAAKGTCRCPGCATYTECNAS
                     NRELLYCYLGKSVGCEMPAKTCDCPVCKVTDDLGLKYSFYCRNGPEKVLRE"
     gene            complement(71253..72347)
                     /locus_tag="PKM11_00445"
     CDS             complement(71253..72347)
                     /locus_tag="PKM11_00445"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HNX47012.1"
                     /translation="MTEEENKAVSSLKEIAQSIYDQIDTGKIPKMTLPLRTKSNIRFD
                     PKHGVFKYGKATGARSAKKVNGALMLLRTMYVLEFLEDMIADKKSSTLREMYYISEGW
                     EKAKFNSQDESNMLAEDLEIVTACLREDFKLRPEENGASIIGDITISEMDRKGRLKTI
                     NCRDDVGDSGYGIPNNVEKEKLQLISTNAKFVVAIETGGMFDRLVENGFDDKYNAVLV
                     HLKGQPARSTRRIIKRMNEEMRLPVVVFTDGDPWSFRIFASVAYGAIKTAHISEYLAT
                     PTAEFVGITASDITNYKLPTDKLTDMDIRALHAELKDPRFADEYWRGEIETMLKLNKK
                     AEQQALAKYGLDFVTDKYLPEKLTNMGVLR"
     gene            complement(72340..74325)
                     /locus_tag="PKM11_00450"
     CDS             complement(72340..74325)
                     /locus_tag="PKM11_00450"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase VI subunit B"
                     /protein_id="HNX47013.1"
                     /translation="MSSIADELAKKQKEISVSEFFERNRHILGFDSQIKSLIMGIKEA
                     VDNSLDACEEAGILPDVVVMVERVDKDEFRVTVEDNGPGIVKKAIPNVFGRLLYGSRF
                     HAVRQSRGQQGIGISATVMYGQITTGKPAVVVSKTGVEDVAWRMEIMVNTKKNMPDVL
                     KEDPFIWDGKEHGTKITYHMNGRYVGGKQSVMEYLKQTAIVNPHSKITFVDPDGKRTT
                     FERATDKMPPATKEIKPHPSGLELGTLMNMSKDTKNKTLGKFLQLDFSRISDRLAKEI
                     CDKAGLSMEVNPAKLSLDQQKALLAAIAAVKIMAPPTDCLSPIGANLIKKGLRNVLDE
                     VRPEFYAPPVTRDPKVHSGNPFLIEVGIVYGGGLAKDSQVQILRFANRVPLLYQQGAC
                     VITKAIENTDWRRYGLEQRGGSGIPFGPAIILVHVASTKVPFTSEAKEAIANLPELQA
                     EIELALKICGRSLKTHLNKRETKSKTKVKFEIVQEILPLIAQKSAKIVGKPIPKLSGS
                     ITKIMNVVWIDDAVTFEKGHQRVRVSIYNYTPQSQKFNLHMVLPPGSFDYKGLQFFPS
                     EVREDGKVSWELPKIASTERLEINFSLNGLNKDDYDENEIYASGINPVFIIGAEPLPG
                     DWDLKGLQITESDEAPVVEDEDEEVDYDESTEALNDD"
     gene            complement(74404..75327)
                     /locus_tag="PKM11_00455"
     CDS             complement(74404..75327)
                     /locus_tag="PKM11_00455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47014.1"
                     /translation="MSIWVGMALALLVTVSLTLTVQLWLAQVVCLLPILVALLAYYIP
                     TYFGLKERKRLAVFGLVLFLVIGLSLGGALYSTVANYEVQDVSSKNSLLVGGTVSPSH
                     TEPGDQLQFSVVLTAGDTNANVSLLLFNNWGEPEDNPNYTMDYSHSTSLGAVYLYNVT
                     SLEEGVYYFQYGVVNGTAWTTTPQTFGPVNAELSKVLTNSLMSGTVYSFYSMAVLFYI
                     LILLTWWMDRSKKKIFEMEQKRAQTKDKKVKDAKEEKFVCSDCGTEVPGEANKCPSCG
                     AKFDDDELSCPQCSAKLLKSDTKCWNCGKKL"
     gene            75427..76395
                     /locus_tag="PKM11_00460"
     CDS             75427..76395
                     /locus_tag="PKM11_00460"
                     /inference="COORDINATES: protein motif:HMM:NF009007.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HNX47015.1"
                     /translation="MAEMRPGEGRMAVLALGGNAILKAGQEARDDVQIANLQVAFRSM
                     LPLLDRYPRMMITHGNGPQVGNILLRNELCHTEVPPMPLDVCVAESQGQIAYLAMQAW
                     DRACRSACREVPMLPIITRTVVSADDLAFRDPTKPVGPYYSKERALVLAREKGWVFRE
                     DVKRGGMRRVVPSPDVVKVAKEEHLRTLVESLTPPFVVLCGGGGGVPVVLSGAGLIGV
                     EAVVDKDLASARLAEVLHADILIMVTDVESVYLDFTSERPRPLRKVTAKELSRHAAEG
                     QFPLGSMGPKVEAATRFVKATGRKAIITSADRLMDALDGKAGTTVE"
     gene            76408..77523
                     /locus_tag="PKM11_00465"
     CDS             76408..77523
                     /locus_tag="PKM11_00465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HNX47016.1"
                     /translation="MASTIEDQIKAIQEEIDKTQKNKATEYHIGKLKAKIAKLKEDVE
                     KRRSSSGGPAKGYSVKKSGNATVALVGFPSVGKSTLLNTLTGARSEVGAYDFTTLDVV
                     PGAYEYMGAKIQVLDMPGLIRDASKGKGRGREVISVVRASDLVLFVLDFYDTNLQVLV
                     RELENAGMRINTHPPDVVIAKRDLGGIDIKTTVKLTKLDLDLAKAMIMEFGMVNADVV
                     IREDIDQDQLVDVLAGNRIYINAVLAINKIDISDAEYLKEVRKKFKHWDPVFISAVKN
                     IGIDELKARIFDRLELIRVYMKKQGEDADLDVPMITKHGATVGDVCDSMHRVFRQNFR
                     YALVWGKSARFPGQMVGLEHRLADGDVLSVIIRRTGE"
     gene            77564..78733
                     /locus_tag="PKM11_00470"
     CDS             77564..78733
                     /locus_tag="PKM11_00470"
                     /inference="COORDINATES: protein motif:HMM:NF013237.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX47017.1"
                     /translation="MSRKGMSTRSVHDGDKSLHYEGAINTPIFQSTTFAFPTEEPRTW
                     NGEIPDGTYIYSRDSNPTVRAVEDKLASLEGAESSLAFSSGMAAITSALLTFLQKGDR
                     LVAMQDLYGGTYAFLKNEMSRLGVDVTFVPTTDPAELCAAIDGRTKVLYLESPTNPLL
                     KLIDIRETCRLAHQKGCLVMIDNTFATPILQRPLELGADIVLHSATKYLNGHSDVIAG
                     FVAGSRKDMAMVHLRRKLYGGVLDPLPAYLLGRGMRTLDLRMRKHDSNALAVARFLES
                     HTKVSKCIHPGLASHPDHELANRQMDGYGGMVTFEVKGGRAAAERALKRFKIIAKAAS
                     LGGVESLASMPVNTSHTSYSSEERQKLGIGEGMIRLSVGIEDPEDLCQDLDQALN"
     gene            complement(78730..79131)
                     /locus_tag="PKM11_00475"
     CDS             complement(78730..79131)
                     /locus_tag="PKM11_00475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47018.1"
                     /translation="MNNDLDHSQGAMLDEDDRRRKARLLQAWADDLDRKGFSDLQVNL
                     ESFPIKPRGYGEHVPDIVATRKDGRRLVGEIWLCESLEKDDQMFSRAMSYAYRGDVVM
                     LLVPFDCLDAAEEMVREWGLSSEIFVQAIID"
     gene            79189..80436
                     /gene="hisS"
                     /locus_tag="PKM11_00480"
     CDS             79189..80436
                     /gene="hisS"
                     /locus_tag="PKM11_00480"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HNX47019.1"
                     /translation="MIQRPRGTRDFGPEEMEVRRHFEDMMRQEAVLHGFREIATPIFE
                     HTELFTLKSGPGVIEEIYAFQDKGGREICLRPELTASVVRFFVSDLATLPRPLKMFYF
                     GQCFRYERPQAGRYREFFQFGAEIIGNATPETDAEAIGLAAAILERTGLQDYRIRVGH
                     IGILREMLAQAGVSGDQASPILQKLDKKIYPEAEELMAQAGIDPQVAQDIISTTKVTG
                     PVSVLDSREGPASDYIRQVCDILLAMGFDNVSVDLGVVRGLAYYTGMVFEVDAPKLGA
                     EKQICGGGSYSLSELFGGEKVFSTGFAIGFDRTLLALQTEGVHFERPGITAFVVPVGD
                     SVRSKAFEIVAELRRSGISADVDLMRRGVGKSLKFAATVPSKYALIIGEKEMESGSVT
                     LRDMNSGEQSLVKMDELVAKLGR"
     gene            complement(80580..81008)
                     /locus_tag="PKM11_00485"
     CDS             complement(80580..81008)
                     /locus_tag="PKM11_00485"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HNX47020.1"
                     /translation="MKFQLFTDGGSRGNPGDSAYAYIIRDQDGQEIASGSNYLGVMTN
                     NEAEYHGLLAGLKELLRRGASEVEVFMDSELVIKQLKGQYRVKAPNLAPLNREAVDIL
                     TGMRTVKVHHVPRENEVITKADALVNWTLDQHNLARQLRR"
     gene            81115..81387
                     /gene="gatC"
                     /locus_tag="PKM11_00490"
     CDS             81115..81387
                     /gene="gatC"
                     /locus_tag="PKM11_00490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HNX47021.1"
                     /translation="MDRETIARVAKVARLNLTEEEMERYAKDLDDILNSFSVLDEAPA
                     GDTYSFNPIPVVDVLREDEPGQDLDPQVLRDQMGTYEGFVRGPRLS"
     gene            81384..82697
                     /locus_tag="PKM11_00495"
     CDS             81384..82697
                     /locus_tag="PKM11_00495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase family protein"
                     /protein_id="HNX47022.1"
                     /translation="MSAIYDLIRYAQLKHRAFTEIVEDLDDTKFHFSAKDNLCADGFQ
                     ARAGSAVLDGYRPPFDATPIRKMKDSGGQLVGKTTMDEFGFGTFSTNSAHGVPLNPFD
                     LERSCGGSSGGAGAAACLIPGHIALGVSTGGSISGPASFCGVVGLTPTYGRVSRYGLI
                     DYGNSLDKVGLLSRSSSLVAKHFRTISGPDPKDPTSCAQPVLADRGKMPRSLAVPKEA
                     LQNLDPAVRSSFQDALSRFKELGTEVHEVSMPSLRFALPAYYILATSEASTNLARYCG
                     MRFGRREEELNQHFNDFFTGVRSESFGDEAKRRILLGTFCRMVGFRSRYYLKSLAVRQ
                     LLIEEYQKVFRDHDAVVTPTMPFIAPRFEEIGRMKTLEMYGADVLTVPPNLTGMPHIS
                     VPCAYVKGLPVGMQLVADHWKELDLLEAASAWEKAFIYRFPEVSP"
     gene            82694..84028
                     /gene="gatB"
                     /locus_tag="PKM11_00500"
     CDS             82694..84028
                     /gene="gatB"
                     /locus_tag="PKM11_00500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HNX47023.1"
                     /translation="MKIGLEMHFQLPTRSKLFCSCPTSSAEPNHNVCPVCLGYPGSRP
                     SLNRKALEAGLGIARFLDCKIEEKVWFNRKTYFYPDLPKNFQITQYESPLGTNGHFDL
                     NGRRIGIWRVHLEEDPGRIRRVGRSGEEIAFVDYNRSGIPLVEIVTAPDLTSPEEARE
                     FIDQLVTELRSLCGLEAQDEQSFRVDANISLGEERVEVKNVQGLRNLERALKFEASRQ
                     SKLLAAGKKVVRETRRFDEERKVTSSAREKETEEDYGYIGEPDLGEFRIGEMARNLDL
                     KETPLVRARRLVSSFGIGEATAKQLVLTSVTLTDLFEELCRHVPPEKAVSWTTGPISS
                     NWAVLQDPGKWPEIVQIVKDDSDGRINDNEAKRRILSLAGVQQEAAVEGGDDMTKLIS
                     DFVDSHPEVLADYRKNPKAANMVIGHVMKESKGRYSSKEVVEEVRKEMDKRV"
     gene            complement(84025..85845)
                     /gene="aspS"
                     /locus_tag="PKM11_00505"
     CDS             complement(84025..85845)
                     /gene="aspS"
                     /locus_tag="PKM11_00505"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HNX47024.1"
                     /translation="MLRTHHCGQLTKGDLGKRATLAGWVRFYRDHGGVLFYDIADSHG
                     STQAVFDPEASNSGDLDRLEKILNNIGREFVVTVTGIVRNRVEGTNDARNLTGEVELL
                     IEDARILSRSKPIPFEVAEQKNSQLPGEDLRLKYRYLDLRRKEMSANLRFRSKLISSA
                     RRYLETQGFIEVETPMLTRSSKEGARDFLVPSRTMPGQFYALPQSPQLYKQMLMVGGV
                     ERYFQIARCFRDEDSRADRQPEFTQLDMEMSFVEMDDILNMVEGMYASVWKDLFNEKL
                     QTPFPRIDLKDALAKYGTDAPDVRFGLEMEEVTDLVKDAPYEIFQKVLSKGGMVTCIN
                     LKANLIKEQDTDGSVGRKQVDRLIEWAKSQGMGGLTWMRMTSEGLSSNIVKYFPEEVR
                     DSIAKRTGAQLGDLLLYLAGPRESVLKAGGQLRLKLARDLGLLEGKGHQFVWLVSCPL
                     FQKDPATGGLTSFHHPFVRPVGDVIPEGKECAKGMGHSYDLVFDGSEIGSGSLRNHDP
                     EMQRKVFGILGMDEATIQREFDFFLEALEFGAPPHGGIGMGMDRLCAMLLGCESIRDV
                     IAFPKNKKFQSLVDGAPTKVEDAKLSELQLLSLADEDEEN"
     gene            complement(86011..86475)
                     /locus_tag="PKM11_00510"
     CDS             complement(86011..86475)
                     /locus_tag="PKM11_00510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HNX47025.1"
                     /translation="MLDELDKRIIEELCKSSQGSSRAIAKRLGIHPTTLIQRVRNLES
                     HDVVRGYRANVDYMKLGYEFMAIVHIYVEGDLISVQQSIKELKNVVAVLDVTGECDSI
                     AWVACRSREEFSQVVKSMLTIKGVKKTNTYVILNVIKDPFNFLPDFSPVEQK"
     assembly_gap    86723..86822
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <86823..87566
                     /locus_tag="PKM11_00515"
     CDS             <86823..87566
                     /locus_tag="PKM11_00515"
                     /inference="COORDINATES: protein motif:HMM:NF019585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HNX47026.1"
                     /translation="IIAAGAEVTCQHVDRENMVEGGPRVKLDRISDRMVRVVSIGEHD
                     SAACAGVHLRNAREVGMLLVSKFTSAKPAGDWEIEFQVGPEAIRTAVDHSVRSLMLAE
                     RMGALPQDSLTAFDNRERELVRAREALKVYGKMALSSLKPERLGEWNYYSGAFTGLDR
                     KLVMEKANEMVAAGSSVAALVCQDDKTFLVLACSTDVKLDCVSILNSVLSNHGGRGGG
                     KPNFASGGTPGQIEPHVLLDKISLLLKNR"
     gene            87698..89041
                     /gene="glnA"
                     /locus_tag="PKM11_00520"
     CDS             87698..89041
                     /gene="glnA"
                     /locus_tag="PKM11_00520"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HNX47027.1"
                     /translation="MPTNKNFDEMKEDILKKVKKENVKFVEMQFSDILGTVKSVSIPT
                     TRVENVIDDGVFLDGSSILGYATIEESDMRANPILDSFQIYPWIDSGVKTARFMCTIS
                     DHSGNRFKGDPRWALEKMVEKVKEMGYDFNVGPEFEFFMFPMKDGVPVPVPADAGGYF
                     DLMPQDKGEIARKEMVLAFDELGYDMEAAHHEVAPGQLEIDLRYNNALTMADRMLTLK
                     YGVKCIAQKHGMYASFMPKPLYGENGSGMHVHMSLSNKEKNAFYDPEGKWGLSDMAMN
                     YMGGLLAHAPSNCAILASHVNSYKRLVPGYEAPCYISWANMNRSALLRVPAGRGMRTR
                     VEQRNPDPAGNPYLQFAVMLAAGLDGIKNKINPGEPIEKDIYHMSPEERRRNKIVDLP
                     MDLGEALDVFAESKVMKEALGEHIFNHYLYIKHREWDDYRTHVTDWEIQRYLRVL"
     gene            89110..89787
                     /locus_tag="PKM11_00525"
     CDS             89110..89787
                     /locus_tag="PKM11_00525"
                     /inference="COORDINATES: protein motif:HMM:NF014626.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HNX47028.1"
                     /translation="MCGRFSLGLVYGFSTRFGVPEVPELKPRYNIAPFQQVPIVVGGE
                     AKSVKWMRWGLVPHWAKGEEFGLKLINVRSESAMDKPMFKTLLNHQRCLVPATGFYEW
                     QRQGNRKRPYHIRVKGQEHFAMAGIYDAWSNGEKDLVTFSILTTAANEAISPIHDRMP
                     VILRREREGEWASREALSADTLSEAFQPLPASMIDAYPVSDMVNDSRADHPDMVVPQR
                     TQQATLF"
     gene            89849..90217
                     /locus_tag="PKM11_00530"
     CDS             89849..90217
                     /locus_tag="PKM11_00530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nascent polypeptide-associated complex protein"
                     /protein_id="HNX47029.1"
                     /translation="MMPGMGRGVNPRQMKQAMKRMGISQEEMQGVEEVIIRTADKEYV
                     IKDAAVTCVTMQGQKTYQVVGDPEVRSRQATKPEDPGIPEEDVQLVMSQTGVSKDKAV
                     QALKECDGQPAEAILKIMSG"
     gene            90235..90441
                     /locus_tag="PKM11_00535"
     CDS             90235..90441
                     /locus_tag="PKM11_00535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="HNX47030.1"
                     /translation="MPAKVLSIVGDEAEVDFGGAIRKTNVSMVDAKVGEYVIIHAGFA
                     IQKVDEEEAKETLQLWNEFLDSTE"
     gene            90497..91204
                     /locus_tag="PKM11_00540"
     CDS             90497..91204
                     /locus_tag="PKM11_00540"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47031.1"
                     /translation="MRIVYGPIRSLGLGRVVAVDPIGRSPKVCNLNCIYCHLGCGGMV
                     LFERSEFIDDASVLDQIGECLHREECESVMFKGTGETLLARNIFHMAKMLREGSDKKV
                     ALFTNSTLLNDPEILEQLDAFDIIIAKLDAASEEKFQTVNRPHPSIRFQDVLEGIKKA
                     RESFAGSFRLHVTVVRENLSDIDNISQICREICPDYVYLESPEGCDPSHTVCKKDMQA
                     AMDRFFGIRCVSSQDKE"
     gene            complement(91233..92171)
                     /locus_tag="PKM11_00545"
     CDS             complement(91233..92171)
                     /locus_tag="PKM11_00545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HNX47032.1"
                     /translation="MNLKSLSHTEDRLVEGHRLCAGCAEPIIARQVLMATDKPVVVAN
                     ATGCFEVSTSIYPFTSWNVPWIHTAFENAPATMSGVEAAYNSLKRQGKLDQEVKFIAF
                     GGDGATYDIGFQSLSGAIERGHDFLYVCFNNEAYMNTGIQRSGATQKGASTTTCPAGT
                     CVPGKKEFPKDLTRIIIAHDLPYAAQASPHNWKDLIEKSKKGIDTPGPAFINVISPCP
                     RGWRHEGSQTIALSKLAVETCVWPLYEYENGVWRLTGESLRIAEGNREKKPVSEWLTS
                     QGRFKHLMKGKFTGVADELQANVDKKWESLLKLCKN"
     gene            complement(92168..93331)
                     /gene="porA"
                     /locus_tag="PKM11_00550"
     CDS             complement(92168..93331)
                     /gene="porA"
                     /locus_tag="PKM11_00550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate ferredoxin oxidoreductase"
                     /protein_id="HNX47033.1"
                     /translation="MSEPMAVNGDMAIAMAWKQINPDVVASYPITPQTIIVEAYSEFV
                     ADGLVDTEYVCAESEHSALSICVGSSAAGARVATATASAGLAFMWEMLYVSASMRTPI
                     VMAVANRTLSGPINIHCDHSDAMGGRDSGWLQIFGENVQEAYDNTLMAFRIAENMKVR
                     LPIMTCLDGFIITHALERFELLEDEKVKAFVGPYQPLRPLLDVKTPTTYGPIAMPEYY
                     YEIKYQIVTAMMNAMDVARQVMKEFAELTGRKYDLVEGYRTEDAEYLMVAMGSTAGTV
                     RYVVDQMRAQGKKVGAVKVRMFRPFPSEDMAKFLKGKKAVAVLDRAMSPGTGAPLYMD
                     VQSSVSRMKDAPVISNYIYGLGGRDIMPGQLNTVFEEIMTGKGERVNYLGVRL"
     gene            complement(93328..93612)
                     /locus_tag="PKM11_00555"
     CDS             complement(93328..93612)
                     /locus_tag="PKM11_00555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX47034.1"
                     /translation="MAENTSSSLAAGGMITEAGSSKKYKTGEWRSERPEVDKKKCTNC
                     LTCWIYCPDNSIIVENEKMVGFKYTHCKGCGICANQCPVKAITMKEEGVE"
     gene            complement(93613..94173)
                     /locus_tag="PKM11_00560"
     CDS             complement(93613..94173)
                     /locus_tag="PKM11_00560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HNX47035.1"
                     /translation="MSTIEIRWHGRGGQGVVTANEILASAALKEGKYIKAFPEFGPER
                     MGAPIRAFARISDEPIMVHSQVYFPDVVLIIDATLLKAGKVVEGLKEGGAIIANFPDE
                     KSKLIHAVGRSENVYAVNATKIALEEIGRPMTNTAMLGALVKVTNVVGIDTIIDEMRN
                     KMSGKLSKDVVEKNLRAIKRAYEEVQ"
     gene            94659..96962
                     /gene="ppsA"
                     /locus_tag="PKM11_00565"
     CDS             94659..96962
                     /gene="ppsA"
                     /locus_tag="PKM11_00565"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HNX47036.1"
                     /translation="MKRIVSISDLGKNDIDIAGGKGANLGELVAAGFNVPPGFVLTTA
                     AYDHFMEASKIGERVHELLAKVDASSERSLQEASVKIRELFDTVEIPADLKEQVLTSH
                     KAMFKGKKMGLVAVRSSATAEDLPTASFAGQQDTYLNVESPEELLDKVRKCWSSLYTP
                     RAIYYRVTKGFEHSKVKLAVVVQKMINSEISGIMFTVDPNSEMPHIIIEAGYGLGEAL
                     VGGKVTPDTYVVDKFHDKILNKRIAKQTWKLVRGGDGECEKADVPEELRNAQKMTDEQ
                     ILALGEIGRNIEAHYDRPMDIEWCIEERVMYIVQARPVTTLSSGAKANGKVQDHGLGQ
                     SAKILLKGLGASPGMAAGPVRIVAEEMNLEVVKKGDVMVTAMTSPDMVPAMTRAAAIV
                     TDEGGMTCHAAIVARELGIPCIVGASHATELLKDDEKITVDGSMGVVYEGIAAPKKEE
                     KAPVAVAAAVPVTGTKVYVNLAIPQKAEEVSKLPVSGVGLMRIEFLFTSYIQEHPCAL
                     IEKGESKFLVDKLADGIAMVAKAFYPRPVILRTSDFKTNEYRDMEGGEKFEPHEENPM
                     IGWRGCSRYVSDSYREAFKLELKAIKKVREEMGLKNLHVMLPFVRTIDEVRKITAMMK
                     EVGLERNRDFKLYLMAEIPCNIFMAEEFAEWCDGFSIGSNDLTQLTMGADRDSDVLGK
                     MGYFDERNEAIKRAINILIEAAHRKGCTVGICGQAPSVYPEFTEFLVKAGIDTISLNP
                     DTVVATINTIASAEKRILLEAARKTLK"
     gene            complement(96970..97770)
                     /locus_tag="PKM11_00570"
     CDS             complement(96970..97770)
                     /locus_tag="PKM11_00570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX47037.1"
                     /translation="MAERKLKVEDYMIRDVVHVPLDFTVRQAVDTLVSSEFHGMPVTR
                     DGKLVGFITAKELLRNYQTPDMPLSDIIRKGTVTVNPKMDLDDAARILFRYGLRNVPV
                     INENGTLLGIISNLDIVRSHIERATPNKVAMIKNFLETKHGVSIMVRRRIVPVESLRP
                     TQKEVYADELLGRKEEIKRGLVEPIIVIQNNENYILVDGHHRALASKQMGVKQFSAFV
                     LEPSRDVELGLEKSAEEQGLYTLDDVKIIDGSHHPLVEITTRLLKSEP"
     gene            97979..98051
                     /locus_tag="PKM11_00575"
     tRNA            97979..98051
                     /locus_tag="PKM11_00575"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:98013..98015,aa:Asp,seq:gtc)
     gene            complement(98295..99374)
                     /locus_tag="PKM11_00580"
     CDS             complement(98295..99374)
                     /locus_tag="PKM11_00580"
                     /inference="COORDINATES: protein motif:HMM:NF013046.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47038.1"
                     /translation="MCGTTAFFYNDDLLRYQFGPEHPYQPIRFKIIRDALRELDVFDG
                     RLEYVESPSATEEDLREVHDRSLIENVKEMSASGTGYLDMGDTPVCHGLFEGALAAVG
                     CTLHGAESIARGEYDHVMTPGGGLHHARADHAAGFSVFNDLAIAARRLQRRFGYERIA
                     IIDIDGHHGDGTQSIFNGEKILTISFHRYGAGFYPGTGAVSDFGEDDGEGYAINVPLP
                     RCTPDEVYAPTYDKVLSAALEAYRPEIIIHQFGTDAHYSDQMVGMGLTTRTYEKVAEI
                     THRLAHEHCDGRYLVTGGGGYSIDAARRIWSIAVCTVSGSFPLNPEGMHLLQDSGLNR
                     KWKVQQDEFHKRMDYLFDEVIPKIR"
     gene            complement(99440..99769)
                     /locus_tag="PKM11_00585"
     CDS             complement(99440..99769)
                     /locus_tag="PKM11_00585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47039.1"
                     /translation="MASRVKLVTPICSHETWVTAEMDGEDRLKVHIESDCSNVMNYAE
                     RLGAITMEDINEQRGSKIMTAAEDGILTPTCLVPIAVMNACWVEAGMISKRLAIKEGP
                     ISIHFFD"
     gene            99968..101056
                     /locus_tag="PKM11_00590"
     CDS             99968..101056
                     /locus_tag="PKM11_00590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47040.1"
                     /translation="MRYQRAIITLMVLALLTVAVPFNAQGETTSEQSISITDSRGVTT
                     NLTGPAVHVASFGAFATNTLVDIGMLDKAVIFDATSEFNKSAIPEMEGVSANHFVTVS
                     SSNKDVVVQTMLDLVDAGKWNKSSDVVLGYGYSYLNTVWADLQGYEFKVVTFYPNSYN
                     GIVQVVKDIETLTGANHSVSAEMTYVRDYIANTLEENGIDNDTERVTALYVSYSSETL
                     KIGNNGSVTVDFINYAGGLNLGENPDKALPTYTADFSALLQLNPEFVLLDGYYAGSAG
                     DFKALINDEDVTVYKLNKSWNSYCPDATDGLWTVACLFYPDYFQGELPVDAGDTGDGQ
                     DNTMIYAGVGVAVIVVAIAAVLLMRRKN"
     gene            101114..102139
                     /locus_tag="PKM11_00595"
     CDS             101114..102139
                     /locus_tag="PKM11_00595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HNX47041.1"
                     /translation="MDSVAKRKRRTTAVFAGLFIVLFIFMILDLAQAFIPLTFEEAFW
                     ALLGRGTETHQIIIWKMNLPRVVMAILVGAGLGIAGAVMQAIFRNPMASPYILGLSSG
                     ASLGAAIGLTFAVTWLPQLLMVPLLAFAFCMATLFLVYYISNVGGKVPTETLLLAGIA
                     VGSLLSALVSLLTYMAGEQMQGIVYWTMGNLTNANWENIMIVAPLIFAGSLIMVASSR
                     DLNAMMLGDAHALDLGVEVKKVRLQLLIASALVTAAAVSFVGVIGFVGLVVPHILRIL
                     MGPDNRALLPASIVGGAAFLMMCDYLSRVIAPNIGILPIGIITALIGAPYFIYLLRRR
                     RSEVGWD"
     gene            102139..102924
                     /locus_tag="PKM11_00600"
     CDS             102139..102924
                     /locus_tag="PKM11_00600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47042.1"
                     /translation="MLTVEGISFSYREKPVLQNVDLEVKKGEIIGILGPNGCGKTTLL
                     KILNRNLKPQKGRVLMEGMDLEEMSKRKIARQIAVVPQSNEIRFAFTVRDIVSMGRMP
                     FLGQFQGESGDDMRIVEEAMEKTSISEFADRPINTMSGGERQRVIIARALAQRPEVIL
                     LDEPTLHLDINHQFEVLDLVRRLSQEEGLTVVIVSHDLPMVVKYCHRMVLIHDHKVHA
                     LGTPQEVLTPENMRVVFNIDAVLEHDMVLNAPAVKIIGSCNRR"
     gene            103000..103341
                     /locus_tag="PKM11_00605"
     CDS             103000..103341
                     /locus_tag="PKM11_00605"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HNX47043.1"
                     /translation="MRQLLRGKIHRATVTAAEPDYVGSIVIDQDLLERADIWPGEKVL
                     VSDVNNAARFETYAVVGKRGSGVISVNGAAAHLVNVGDKVIIMAFELTDRPIPSKVVL
                     VDQNNHFIRNL"
     gene            103407..103901
                     /locus_tag="PKM11_00610"
     CDS             103407..103901
                     /locus_tag="PKM11_00610"
                     /inference="COORDINATES: protein motif:HMM:NF024806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HNX47044.1"
                     /translation="MATVDFDKLMKDGYRLMEEGEYSKALTKFDAAIKADPTNPSAFL
                     AKADAGVLVPKVTQEEIVALYKKASELDPENPFILQSWGAFCMDIGLFNDAEACYNKA
                     AQIDPENATYYYSEFGVEYHKKALIVYESRLDEQTRAIIAKKALKYLLKSIDLDEASA
                     KKLL"
     gene            complement(103902..104084)
                     /locus_tag="PKM11_00615"
     CDS             complement(103902..104084)
                     /locus_tag="PKM11_00615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47045.1"
                     /translation="MEVIGLCSICSRPARYSCTMCGRLVCPSHYDTHGRLCDQCSPER
                     KNERLRRDGPERHLLQ"
     gene            complement(104122..104796)
                     /locus_tag="PKM11_00620"
     CDS             complement(104122..104796)
                     /locus_tag="PKM11_00620"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: protein motif:HMM:TIGR01487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008967 - phosphoglycolate phosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HNX47046.1"
                     /translation="MGYRAVVCDVDGTITDPSKIIQTLGIEVLRKAQDRGRVVILASG
                     NVLPVVYGLSTFIGLRGPVVAENGGIVSYQDEVHTLFSNEVPLQAYEHLRTVMPGVRR
                     LFTDQWRRTEVGVNREADLTEVLEALRDWPLEVEATGFAIHLMQRGHSKMAGVRKACE
                     LIGVDVSEVVAFGDADNDALMLKECGYGVAVGNASDKARKAADLVTKGKHAEGVREGL
                     ISLGLI"
     gene            complement(104799..105680)
                     /gene="mptA"
                     /locus_tag="PKM11_00625"
     CDS             complement(104799..105680)
                     /gene="mptA"
                     /locus_tag="PKM11_00625"
                     /EC_number="3.5.4.39"
                     /inference="COORDINATES: protein motif:HMM:TIGR00294.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase MptA"
                     /protein_id="HNX47047.1"
                     /translation="MSKSDVQNRYLTNGFKLTRVGVTGVKKPVRVHRDGRDTCLTCEI
                     DVYVDLPSTQRGSHLSRNLEVIAEIVEQGVSQPIKGLEVLASDICRRLLDRHEYASYA
                     EVHIKGDYFLERSLPTGRKSIESYKLIARATHKRGDGLLKMIGARVIGMTACPCAMES
                     VDEIQGNTLKQVGCLPTISHNQRNVTTAMLEVPEEFDVEVDDLIEIVEASFSSPTFEI
                     LKRKEEANVVINAHRNPKFVEDVVRDNLALILKRYPQLPDDTVVTVRSESEESIHKHN
                     AVAERVTTLGELRSDLV"
     gene            105814..106455
                     /gene="rnhB"
                     /locus_tag="PKM11_00630"
     CDS             105814..106455
                     /gene="rnhB"
                     /locus_tag="PKM11_00630"
                     /inference="COORDINATES: protein motif:HMM:TIGR00729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HNX47048.1"
                     /translation="MICGLDEAGRGPVMGPLVVAAVMVEDDRLFREWGVKDSKLHKPE
                     ERERLAELIQANSTWKVVMIDPGSIDERKGTTSLNTLEIRAFAALIDDLRPQIAYVDA
                     CDASEQHFKTALARACRFRTELICEHKADLNYPVVSAASIVAKVRRDAEMRRIGEEIG
                     EVGSGYSSDPRTRAFLENWIREKGDLPPYTRRSWATAKDMLCSSKTSKLSDWE"
     gene            106457..106789
                     /locus_tag="PKM11_00635"
     CDS             106457..106789
                     /locus_tag="PKM11_00635"
                     /inference="COORDINATES: protein motif:HMM:NF014132.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="HNX47049.1"
                     /translation="MTTKDHLLNAIDKFNGKMQCDAQLREEVGPLVKKVNIELGTENY
                     SFLLKDSCISCLDEGLMECPDIVVCSDPRTIDELFTGKMKPMKAWALRKVVIRGSLED
                     VMKLRKFF"
     gene            106853..106927
                     /locus_tag="PKM11_00640"
     tRNA            106853..106927
                     /locus_tag="PKM11_00640"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:106888..106890,aa:Met,seq:cat)
     gene            106986..108509
                     /gene="glpA"
                     /locus_tag="PKM11_00645"
     CDS             106986..108509
                     /gene="glpA"
                     /locus_tag="PKM11_00645"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: protein motif:HMM:NF008313.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0046174 - polyol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HNX47050.1"
                     /translation="MRKDVLVIGGGATGAGIARDLAQRGVECLLLEMGDYCHGASGGN
                     HGLLHSGARYAVKDAVSASECAAENIVLKEIAPFAIEDTGGLFVSLPEDDPDFVDLFT
                     TSCRSAGVPTEELTSKEAIACEPGLDPKVVSCFKVPDGSVDPFSLVQANMDDARSAGA
                     TVLNHCAVSGMTVQDGRVVKVEVRDRRGGLPSSIVPELVVNAAGAWVADVASMAGCHV
                     PMGLDQGSMLVLDGRQCRHVMNRLRQPSNGDIAVPNHTSTILGTTSRLARSPNDVAVS
                     KEDVELLIKEASAMLPSLRECRAIRTYGGVRPLLGGGGREASRSFAIMSDDKVDNLLS
                     VAGGKLTTYRLMAEKVSDRVCEILGNGANCRTHLEKLGPAPDPKGGSISSARLRRKYG
                     RAATSIDTADTRVLCSCEQVMRSEVTMVLSKGDALTLADVMRRTRAGMGYCQGFDCSL
                     SVLEVMIERNQVDPVPSLKEFLEERERGLTQATGDQLRQEILRRHVLRGVYGLEGKE"
     gene            108506..109555
                     /locus_tag="PKM11_00650"
     CDS             108506..109555
                     /locus_tag="PKM11_00650"
                     /inference="COORDINATES: protein motif:HMM:NF013086.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HNX47051.1"
                     /translation="MNRVLVVGKGAAGTFSSWLLANKGWEVILVGRGTPSTAMSTGCL
                     RSQPNVCRSEIMEFLNNEMMPWTYGSREGMSKIGTSYRCWMSPPHSTWKEGEAPKSVA
                     VVGLEGHPSLQARVASATLNARGIRAESLILPSSVPSDVPLAASLFSDESWETLADEL
                     QRQSAEAILLPAMVALEDYHQLDILELRSGRRVLEAITPLSAPGQRLGDIMRSKAAGS
                     GVTIWDGRKVTALDVRDGEVRGATVAGGQEVRDILIDAVIIATGGPLVDGLALKERNI
                     SDPFGMFQVVRSNDGLRGGYDSSNGMLIASDGHPMNNVAGAGDCLSSERREYGSGLTE
                     ALEGAYLAVQALEGS"
     gene            109552..110535
                     /locus_tag="PKM11_00655"
     CDS             109552..110535
                     /locus_tag="PKM11_00655"
                     /inference="COORDINATES: protein motif:HMM:NF014774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heterodisulfide reductase-related iron-sulfur
                     binding cluster"
                     /protein_id="HNX47052.1"
                     /translation="MNEGRCVKCGSCLRVCPVLNDLSGSPFPGPRTVGVDAPRFLERE
                     SVGHNALRCTMCHACEWACPSGITLTRSMLKLRSGMSGERLPGHRRMLENISSFGRSV
                     NTEFSGWIEKGNRTLYFPGCIGLGRSADLTRTVSSLLTSLGIEHDISSQVLCCGSPLL
                     KIGATEVAEDLRRRNTEALSRYDRVITSCPGCTYQLREFYGIEAEHVIEVLKGLDLRS
                     KLEGRWALQIPCHLRRGLSPWAAEDLIIILENAGVDIVRMPQEDSCCGGGGGMLSGFP
                     ETSGSIARHKVDMYRRAEVDGVITACPFCSLNLGREGLKVLDITEAITLNK"
     gene            110554..110778
                     /locus_tag="PKM11_00660"
     CDS             110554..110778
                     /locus_tag="PKM11_00660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47053.1"
                     /translation="MHDRTRQMNKALCFSCLHRENRPELGLSDQLVYCRKKEMVVRPK
                     MECTLYSKATARAVQELNRALYGVMEEAED"
     gene            complement(110779..111459)
                     /locus_tag="PKM11_00665"
     CDS             complement(110779..111459)
                     /locus_tag="PKM11_00665"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RAD55 family ATPase"
                     /protein_id="HNX47054.1"
                     /translation="MFRTNFPQMCSVLILGTPGVGLLEFQMSMVKEYLDQGEPVVFVT
                     MDLLPRDLFTSMERFGISLDLLGKGLYVIDYHSSLLGNGDDREAGDRTKVRRIHDLEG
                     IMFNVANIFAEEKRPLRVFMHTLSTLFLYNQASVVLKFFQISTSRIRSEFGTAIVSVF
                     DGVHEEKALNHLVALADGVIELRFDNDLNRVLRVRHMRGMSVPGRWIPFEITPGGEEA
                     PAPVLEWK"
     gene            complement(111470..112903)
                     /gene="gvpD"
                     /locus_tag="PKM11_00670"
     CDS             complement(111470..112903)
                     /gene="gvpD"
                     /locus_tag="PKM11_00670"
                     /inference="COORDINATES: protein motif:HMM:NF018756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gas vesicle protein GvpD"
                     /protein_id="HNX47055.1"
                     /translation="MPDPSNSALPNEITRFLENPGGHSLIVRGNAGTGKTTFVLQVAE
                     EFKDRQRAHYLSTRVSDSSLLRQFPWLADRLITREETSTRRRSGFGRLKGVGSGDLLV
                     SRKEMTVSIGRTMPDLENLYDLVEKAGERVLVIIDSIDALADRYELQCRELMIALQRD
                     LVEGQGANLLFVLENNDHMLDYLGDGVVECTRMEHERRLVREMDLMKLRGVEVQQPLY
                     LFSLKGGKFRCFGAKWDRGSGMSNEFARPEDPAGHLSFGITDLDEMTGGLFPGAVTLI
                     ELGGGLPPLVSGILERSLVSSFAKAGRGVLWVPLRKESGAGARGMLQNVLTDGEMEKT
                     VRVVEPASQMDQGSGRYVMAVEGTRVSDDLKWKNIVYALNGSSQPFLSLMGFDSLESI
                     YGGEVMEGLIDHLAAVKRNGGSFVGLTSPTSRSTARLADLATVHLKVERIGGTVVLYG
                     SKPFTECFALTVEERPQGGCVSLTPLV"
     gene            113039..114229
                     /locus_tag="PKM11_00675"
     CDS             113039..114229
                     /locus_tag="PKM11_00675"
                     /inference="COORDINATES: protein motif:HMM:TIGR03992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HNX47056.1"
                     /translation="MKAVILAAGEGTRLRPFTVSRPKVMIPIGNRPILEYVVRALAAN
                     GITEIILVVGYMKERIMSFFGNGSRFGVKISYSIQEKQLGTAHATLAVRSQIKDDFIL
                     VAGDNIIDAQVIADLLNHKGGLAMLVTDSEIPSKYGVVQIESGQVVDIIEKPDKKVGN
                     IINTGIYRLPPTIFDHLEKGIMAGKSGITHVLHSCMPRLKVDAVRSTGRWMDAVYPWD
                     LIRLNEYAFSLSGQETSGTIESGVTMRGPVYVGAGTRIRAGCYIEGPVSIGEGCEIGP
                     YVTIFPTTSIGNGVHIAPYTYINNSMIMNNVSIGSHAHISRAVIDDGCRIMTGFSAPS
                     GLAQVRVEDDFFKVEKAGSMVGEFTQIGPQVVLSAGTIIGANSRVGDGAKVSGTLENR
                     SLVV"
     gene            114229..116025
                     /gene="glmS"
                     /locus_tag="PKM11_00680"
     CDS             114229..116025
                     /gene="glmS"
                     /locus_tag="PKM11_00680"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HNX47057.1"
                     /translation="MCGIVGYSGHRRASEVLMEGLKRLEYRGYDSAGVAIVEDGRLVL
                     LKKQGELEVLQKALPKFEGRTGIGHTRWATCGRPSDRNAHPFVSCDGKLAIVHNGIIE
                     NYTALRERLESEGHHFTSETDTEVVVHLMETHYTGDLRQALADTTREIQGTYAIAAVL
                     EGSLEVAAARKENPLVVGLGVKENFLASDVTALLSYTNQVLYIRDGETVSLTPKGVTV
                     FDQDGAIVKRETSVVTWSAEDAQKGGFEHFMLKEIFEGPNAIHNTLLGALDLIENGDV
                     IPRMDFSSVKLVACGSSFHAAMVGKYAMEEFAGIPTTLELASEYRYSPGTREAPLVIL
                     ITQSGETADTLAAAREARRRGCRTLAVTNVVGSTITREVDEVLYTKAGPEIGVAATKT
                     FLTQLLAMYMLAIRIGYANGTLSHDAMRSALSSLRQSSNMVQSVLNHMHEIEEASKMI
                     DESEHCFFIGRNINYPTMLEGALKLKEISYIHAEGFAAGELKHGPLALLDSKTPVIAV
                     AIKGDHTYEKMLANISEVAARDSPVLGVGLEGDTDLSRLCERMIYVPPVKPVFSPIPV
                     TVALQALSYYVAKRRGCSIDKPKNLAKSVTVE"
     gene            complement(116026..117015)
                     /locus_tag="PKM11_00685"
     CDS             complement(116026..117015)
                     /locus_tag="PKM11_00685"
                     /inference="COORDINATES: protein motif:HMM:NF024117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HNX47058.1"
                     /translation="MDRTEVISASDLERYGYCPLSWWLGRKSQSSTPEQERGDAAHRD
                     KADEYRRIRNIEQKAWDWERMVFLFSLVATVLAVTGISLMRAAGSVNIGWILPLLSII
                     WFLAVIAMLYLSALRGRAIIQVRRLQIVAMVGLVLMVVAMNIGNLIQADPMVSMILEA
                     LALVWLIAASLALYLSLSASQKVGERMNAEGLEGEIKYVGTDDSQLYLSERYGLSGRP
                     DFVLEIDGQLIPGDLKTGRTPKGPLFSHILQVATYCLLIAESSGKRPPYGLLLYGSEE
                     HEIEFDAELEKILLEKVDEMRKLMRSGEVHRNHNRPGKCASCSRRESCPEKLV"
     gene            complement(117061..117822)
                     /locus_tag="PKM11_00690"
     CDS             complement(117061..117822)
                     /locus_tag="PKM11_00690"
                     /inference="COORDINATES: protein motif:HMM:NF026161.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030218 - erythrocyte differentiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TPD domain-containing protein"
                     /protein_id="HNX47059.1"
                     /translation="MKNEDFKYLYDRLKEPSDIDVLSKELNLDRELLTVIYSQRTQRE
                     SMKRHYKVKRDAPRLLRSWRSGETLLEIARRYEFPPVLTGLVLFNESGRSNKQYWALV
                     RNPEAITDKELRRQIEEITAADIINSPEGDLKQKLRGKWGEKNLQDWLDSQGITYRTE
                     NDLRGSFTKTPDALLDKPIMVNGWKINWIESKASFGDFVEVNKNTKKQLSPYVELFGQ
                     GLVVYWFGFVDEITMEDGIYITDASLTGLNCRYLE"
     gene            117981..118592
                     /locus_tag="PKM11_00695"
     CDS             117981..118592
                     /locus_tag="PKM11_00695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47060.1"
                     /translation="MDLNNFLASENGPPWLPASVAEARKLVYIGQLFALIFALIALVI
                     GVLNIISGTLYTGAYSLVAAALGMVLLFMLKKQVFANLDQGRFKQASNSLLIWTVVGF
                     FVWVIPGLILLIGFLKLQGVFQLQYQDYQAQQYQVAQEPQAQQAPPAQPAPAQPAPVA
                     PEQPAPAPAEHKEKKVEMAKCRKCGVNYPAFMHNCPNCNEPRH"
     gene            complement(118589..118816)
                     /locus_tag="PKM11_00700"
     CDS             complement(118589..118816)
                     /locus_tag="PKM11_00700"
                     /inference="COORDINATES: protein motif:HMM:NF016352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA repair domain-containing protein"
                     /protein_id="HNX47061.1"
                     /translation="MTYPRQVLSKLRWGDGGLHDVVITYIHRGGPDDLASVKGESITD
                     LDRSFFTVGEGQIPYHRIVKIEKKGEVVFQA"
     gene            118877..120502
                     /gene="ade"
                     /locus_tag="PKM11_00705"
     CDS             118877..120502
                     /gene="ade"
                     /locus_tag="PKM11_00705"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR01178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HNX47062.1"
                     /translation="MSRKSVEGQLVDVVNGKIVPSRVIMEDGKFSEIVALPDAPKRYL
                     LPGLIDSHIHIESSQLCPSRFAEAAVPHGTTAVVSDPHEIANVLGMNGIELLLEDAAN
                     VPLRTYLTAPSCVPATQYERSGATIGVAEIEAMLKDPRFVGLGEVMDVQGVLKYDPLI
                     IAKIKAAKSFWKGIDGHCPGLVGKDLVKYINAGMRTDHESLTADEAEEKYFLGMWIQV
                     REGSASRDLLSLMPFAKTHECMLVSDDLRARDLVNGHLDVLLRKAVALGMPPMHAIRA
                     VTAWPAWHYNLPGGSVAVGRTADLVVVDDLRNFNVLQVYIAGRLVAEDGVPLFLAEPR
                     TNGLGIMPRDLVGEDMLLPAEGQKVSVRVIEAFPDRIESGSLVTELPVRGGQVRALPE
                     QDVLHMALVNRYVEERPVLGFVKGFGLRRGAMATSVAHDSHHILAVGASIDDMARAIN
                     AVSRSGGFAVCDGSDISTLPLDLAGLMSTSPARVVAQKESELVDMLAGMGCRMPAPFM
                     TLSFQSLLVVPELKMSDRGLFDTRRMVVVPPLL"
     gene            120558..121244
                     /locus_tag="PKM11_00710"
     CDS             120558..121244
                     /locus_tag="PKM11_00710"
                     /inference="COORDINATES: protein motif:HMM:NF012383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="HNX47063.1"
                     /translation="MDKVESFKCRILTWDEIARWTEAVANDIADNGFRPTVVIGLTRG
                     GWVPARVICDHLQVKRLYAVKTEHWGVTANTDGKALLTQELNASIVGESVLIVDDITD
                     TGESLMLAEKHLKAMGPKEVRTATLLHITHSKKQPDFFEVEVPKEDWTWFIFPWNLHE
                     DLRTILPKTLYQPQTVLGIQKGFKEQFQIDVPEDLIRRTLKHLTVSGKVKKKGAKWQR
                     TDGDEALPRK"
     gene            complement(121245..121547)
                     /locus_tag="PKM11_00715"
     CDS             complement(121245..121547)
                     /locus_tag="PKM11_00715"
                     /inference="COORDINATES: protein motif:HMM:NF025178.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="HNX47064.1"
                     /translation="MKVLVGKDADIKEGRLRSVMVDGRKFVVGRYQGQLFGMDGKCSH
                     AGFDLAYGTVRDGAVVCPAHGATFDVHDGKKVTHSGAKDLRVYIVSLEGDDVYIEI"
     gene            121638..122192
                     /gene="hpt"
                     /locus_tag="PKM11_00720"
     CDS             121638..122192
                     /gene="hpt"
                     /locus_tag="PKM11_00720"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine/guanine phosphoribosyltransferase"
                     /protein_id="HNX47065.1"
                     /translation="MLEKLKESLERSDIVRFGEYQYFVHPITDGIPAMDPQVLDEVLD
                     RIYDLLDLNVDYLVGAEAMAIPLIVPLSLMTGIPYNVVRKRRYGLPGEVSVRQTTGYS
                     EKELYINGLKKGDRVIVLDDVVSTGGTLRAIVKALKTMGVDVRDIIVVVKKTDKLEEL
                     EKDIGQKVRTLVSVEVKDGKVHVI"
     gene            complement(122185..122973)
                     /locus_tag="PKM11_00725"
     CDS             complement(122185..122973)
                     /locus_tag="PKM11_00725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47066.1"
                     /translation="MSLISNISWRSLALWKRNRDVFLTTWKTNFLPPFLEPILYLVAM
                     GLGFGALIQADIVYGGESVEYIKFLAPGLVAISIMYGAFFECTYSSFVRMYYQKTFDA
                     ILATPLSLEDIITGEILWGATKSFVNATIVLGVIAVLGYAELPGLLLIPLIAFVGGLM
                     FASLAMLFTALVPNMDSFNYPFFLFITPMFLFSGTFFPLSVLPEWGQQLAMTLPLTHI
                     SNMTRDLSYNMLTTEVAIGAAYIIVLTAVCFLGSVYLMKKRLVK"
     gene            complement(122970..123878)
                     /locus_tag="PKM11_00730"
     CDS             complement(122970..123878)
                     /locus_tag="PKM11_00730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HNX47067.1"
                     /translation="MPAVRAEKLTKVFDELRAVDAIDFQIEEGECFGFLGPNGAGKST
                     TMRMMHCASPITSGKLEVLGMDVNDRSRDVKAVIGVAPQENNLDPDFTVRRNLTVYGR
                     YFGLPKDVLEERADRLLEFMQLSEKRDERIQEISGGMKRRLIIARAMMNDPRLLILDE
                     PTTGLDPQARHLIWEKVRELKRKKVTVILTTHYMDEAERLCDRLVIMDHGKIILEGKP
                     RDLIDSVIGTDVMEIDVPTDEMEAYVKGQGWQYERTIDRLLIFTKEGQKTAAEIKERF
                     AMSYYLIRNATLEDVFLRSTGRALVE"
     gene            123975..125507
                     /locus_tag="PKM11_00735"
     CDS             123975..125507
                     /locus_tag="PKM11_00735"
                     /inference="COORDINATES: protein motif:HMM:NF014073.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HNX47068.1"
                     /translation="MFGADLLLLLYFTLFGMGLGALSGLAPGIHVNTLAVLLIMSVPA
                     LSPFLEDICGSVGCSLPPALLLSCTIFSAAICHSFLDYIPSLIMGVPDETECMSVLPS
                     HKLLLEGKGMNALQAAAQGSLVGAMAGMIVLLPLPFVHLQATSVLNAVTPAIPWLLLA
                     VPFLLFWAESGKADPKAELDMRGGGSTPAEMISLKRHIPVHGDSARVIGSVNRHHGRW
                     YVRTPLQTFRIRGRWMEAGDQTLIGKWIVRKDRLPISGWSVLLFLCSGILGVMAMDGL
                     VPGEDIWKGMEGNMLMPLFTGLFGLPLLIGSSRGRMPEQDGEADVSPSVTGALKGSFM
                     GGLVGWLPGVTATAGAVLSTMLPRSRGGPEEFISTVSAVGTGAAVLGLGTLLLIGKGR
                     SGTLLAMQEAMPSLSVTEMPSLLLCILFTSLVSYVLTMRLGRKLLVKAQGRDLTKLNQ
                     GALIGMIVLSFVLAGPGGLLLLTLSTILGMVPGKIGISRVHLTGCLLLPILLYYFAPF
                     LR"
     gene            complement(125483..127639)
                     /locus_tag="PKM11_00740"
     CDS             complement(125483..127639)
                     /locus_tag="PKM11_00740"
                     /inference="COORDINATES: protein motif:HMM:NF012364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase domain-containing protein"
                     /protein_id="HNX47069.1"
                     /translation="MRGWILDCYADEVNNEMVTWIKTSTGMERITDREYRPCFYVKPS
                     SERRQDLLLGLKEAGVEHRWEKHRTWLTGPLEDVLKVSPRGYRNLMPLAKTIDKWGCH
                     RDHTLFNVDTRMDTRYFLHRKVFPMGLMDVDRWKNLDTPFRLDYPMPELRTCELTLET
                     SVRRGMPTMEDHLKRATLDDIVMEGKEADILELLQQALREKDPDVLVTDGGDSFHLPF
                     LEKCAERNEMELELGREGGKRRGKAKSYFTYGRILYKPPAYKLRGRIHLDKGSSFIFQ
                     EGKMAGLIDLSRLSRISPQDMARMSPGSAISAMQVNEASKMGSLVMWKKNLPEDFKTA
                     AELVACDRGGLIYEPKVGLHEHIQEVDFTSLYPSIMVRHNISPETLNCDCCQDSGEPV
                     PGLGYWTCSKRKGLLGRVLEPIVRRRISLKRLKKEGGRRSAIYDQQAKVLKWVLVTCF
                     GYTGYRNARFGRIECHESITAHGREILLKSAEVAENRGFRVLHGIVDSLWLSGNGDIE
                     AYCREIGQRMGIPLVWDGEYKWIVFLPNLTNGAGALNRYYGAFQDGELKVRGIALRRR
                     DTCTLARELQQGMLDRLVLGEDAEGFRHRIPEALDVLDSFIRNLRNMEVPLEKLVLSK
                     RITRELNDYRQKNDQFRALAQLEDQGFRTPPGEAVEFIMIKGKEVKVAQFLEGDEEYD
                     IGRYEELLFRTAGELLSPFELGQDRLRDFYRRNGAK"
     gene            complement(127644..127883)
                     /locus_tag="PKM11_00745"
     CDS             complement(127644..127883)
                     /locus_tag="PKM11_00745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47070.1"
                     /translation="MGRTVPTYRMASETLFQSWSDFRRALSQEDRAAFDRLSDKVRLH
                     ASACSIAAFLDPLEGALLSILLEQEKELERLRKKA"
     gene            complement(127883..128620)
                     /locus_tag="PKM11_00750"
     CDS             complement(127883..128620)
                     /locus_tag="PKM11_00750"
                     /inference="COORDINATES: protein motif:HMM:NF020014.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47071.1"
                     /translation="MYRSMPEMVTEPLVHDLHSVTDGMLATTAIPPVDELLGGLEPGT
                     VTTIDSSDKLLFNLVNMLSVNFVREWHRDVVWVDGGNSVNPYDLTYVCKRFRLRPEEV
                     LNSINVSRAFTAYQMSTLVEESLEDELVRNKGGMVVVSCYPDLFQDADMDWEESLKLM
                     ERGMGKLRSLTEKHRTVSVVTNYGLAKLMYRKGLRSLFYEKVDRVVSVEHRSGYVRIS
                     LPREEKEIMYRPVPPNQTTLDEYRRRF"
     gene            128787..129800
                     /locus_tag="PKM11_00755"
     CDS             128787..129800
                     /locus_tag="PKM11_00755"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF019159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47072.1"
                     /translation="MDRDGPSVQLGNGIEVACGDTRFFLDPRRVSTEGICCISHAHSD
                     HMPSSFANGPIHCSDITLRCMRGRVKSKKSKTFLEGVELGNDPLVKASGAGHILGSNM
                     FLLDAGQKVLYTGDFCPQDRLDIEGARPQKCDVLIVEATYGNPRYRFPDRREMIKVIH
                     DWVGDMINQGYSAVLHAYPLGKSQELITMLKDFQPRLHGSVLDTTRLLESDDLKFDYV
                     PFDPMDSEPQLVISPGAWGENGLSMLKKKRSADVSGWCLDNGGRSMGKMSWGMDQGFA
                     YSDHADFYEIIDFVEKCSPSLVYTNHGSEDMLAQEIQKRLGITAIPLKKEKKGQTNLG
                     CYC"
     gene            complement(129791..130747)
                     /locus_tag="PKM11_00760"
     CDS             complement(129791..130747)
                     /locus_tag="PKM11_00760"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided pseudouridylation complex
                     pseudouridine synthase subunit Cbf5"
                     /protein_id="HNX47073.1"
                     /translation="MLVRDKDPRVVERGKRPEDRSIQELLDGGVIVLDKVQGPTSHQV
                     TAWVRDILGVEKIGHGGTLDPNVSGVLPIALGKAIRMTDLVLRSNKQYVCHLYLHRPV
                     AEEKVRSVIETFVGSIYQTPPVRSAVKVAMRIRKVHSIDILEISGRDVLFKVDCDAGT
                     YIRTLCVDIGDALGVGANMRALRRTRSGAMTELDAVTMQDLKDAVVDWKNGDEKWLRT
                     MIRPMEALLEPLPKVIVKDHAVDAIAHGADLNAPGVVSLDENVEKGSPVAMFTVKGEA
                     LGLGTANMSARDMYKAYKGKAVKTVRVFMPEGTYPRMWGAQQ"
     gene            complement(130749..131279)
                     /locus_tag="PKM11_00765"
     CDS             complement(130749..131279)
                     /locus_tag="PKM11_00765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HNX47074.1"
                     /translation="MRITISGMIGSGKTTVCRMLGDMLGYRTVISGLVFREMAKELGM
                     SLEEFGDLAEQDPKYDRLIDQRLLDVAKSEDNVILEGRLAGQMLRRNFIPAFCIFLDA
                     PLEVRVERVSGREGVDMRAAMDEMCSREASEVLRYRKFYDIDVTDRSIYDMVIDTGSL
                     TPEQVVESIVSRIRSV"
     gene            complement(131276..131929)
                     /locus_tag="PKM11_00770"
     CDS             complement(131276..131929)
                     /locus_tag="PKM11_00770"
                     /inference="COORDINATES: protein motif:HMM:NF014061.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EMC3/TMCO1 family protein"
                     /protein_id="HNX47075.1"
                     /translation="MAELPATDRKSTTSRMLLIFVFIMAIFVMFDRDLRTALGKIVGY
                     GLEPLWGFDGSIPVVSLFITGAFMTTLSIVVRHFFTDYVKQTRSQKIMSAFNKEMSAA
                     RKENNTYKLKKMMELQPKMMEESMKQTTSQMKLMPVTMLIVIPIFAWLAVFVGNLDSA
                     VITVPWSNFADLNKSYVLPAWVLLYSLISVPFGQLLSRGLRYYTFKKRLNVLKAEGQ"
     gene            complement(131936..133516)
                     /gene="secY"
                     /locus_tag="PKM11_00775"
     CDS             complement(131936..133516)
                     /gene="secY"
                     /locus_tag="PKM11_00775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HNX47076.1"
                     /translation="MADDQKSKLYKLKPITDRLPAVSKPEGHVHFRTKMLWVVVILVF
                     YFIMTNIFLYGLDGDKTIDLFAQYRAILAGAQGSLMHLGIGPIVTASIIMQLFVGAKI
                     IKLDLTNKEDKAVYQSSQKFLVLVMILVESIPQVFGYLVPSSAFVGGMEGTFGDSGIL
                     RGENIARLIIIIQLCVGSYLVFLMDEVVSKWGIGSGISLFIAAGVAEALFTGTLNTEG
                     LQTDQPLSNSNLPIGSIPKTIYILTHQSASELVGGGYEQMLIANPNPLIALVGTIIIF
                     LFVAYVESSRIELPLAHGTARGARGRYPIKLVYASNIPVILMAALLANISMFTMLFYT
                     NDALNGIPLLGGNPLLGVYPAGATHPTSGLAWYLSTPNGVGDWLLPILNPGSYGNMVY
                     GHSTWQVIAHVLVYVGIMVGGSVLFAKFWIMTTNMGPEAVARQIESSGLQIPGFRRDP
                     RVLKRVLERYIPIVTVISGALVGGLAAGADLIGTVGNASGTGVLLSVGIMIQFYEAMG
                     REQMMEMHPVMRGFFGGE"
     gene            complement(133533..133961)
                     /locus_tag="PKM11_00780"
     CDS             complement(133533..133961)
                     /locus_tag="PKM11_00780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uL15m family ribosomal protein"
                     /protein_id="HNX47077.1"
                     /translation="MVSRTDKFRGSRTHGRGKKAGRGAGKRGGKGNAGLHKHKVQYML
                     KYMPDHFGRHGFKRPQKMVSAKITMNVGDLEQILDVMKAQGTAVEKDGVMTLDLTALG
                     IDKLLGNGQVSTPFKVLVAETTVLAKAKVEESGGHIVVPE"
     gene            complement(133973..134437)
                     /locus_tag="PKM11_00785"
     CDS             complement(133973..134437)
                     /locus_tag="PKM11_00785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HNX47078.1"
                     /translation="MAYAAIRVRGHSGVRHDVEDTMRMLRLTRANHCVILAETDEIKG
                     MLMKAKDYITWGEVSDETLARMIKFRGRLMGDKPIDDEVVKDSTPFGSIMALAKGISN
                     GETKYSDMKDVKPIFRLSPPKKGYEGVKRGFGAGGALGYRGEEINDLISRMI"
     gene            complement(134440..135117)
                     /locus_tag="PKM11_00790"
     CDS             complement(134440..135117)
                     /locus_tag="PKM11_00790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HNX47079.1"
                     /translation="MDWVPKTRLGKMVLNGEITTMSQALATKLPLREAEIVDILLPDL
                     KDEVIDVSMVQRMTDSGRRVKFRITCVVGNGDGFIGIGRAKGKEVGPSIRKAIDNAKL
                     NIIEIKRGCGSWECGCGTPHSLPFTVVGKSGSVEVYLKPAPRGISLAVGDVAKSILTL
                     AGVKDSWGFARGNTKTTVNYAYATYYALRNSIEMRVSEEQEKRQHIVSGPVQLHVEEQ
                     SAPGQEE"
     gene            complement(135119..135619)
                     /locus_tag="PKM11_00795"
     CDS             complement(135119..135619)
                     /locus_tag="PKM11_00795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HNX47080.1"
                     /translation="MAQGPRYRVAFRRRREGRTDYRQRQRLLRARVPRAVVRVSLRHV
                     SIQIVDFDPQGDQVLATAHSRELLEMGWNKATGNVPAAYLTGYLAGKKAMAKGISEAV
                     LDIGLKVPAKGATVFAALKGMVDAGMKIPHGKEVLPSKERLAGKNIGDDVEKMIKDIK
                     TRMEAN"
     gene            complement(135619..136074)
                     /locus_tag="PKM11_00800"
     CDS             complement(135619..136074)
                     /locus_tag="PKM11_00800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015492815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19e"
                     /protein_id="HNX47081.1"
                     /translation="MDLKNQKRMAAEVLKCGENRVWIDPNRIEDVADAITRADIRTAI
                     LSGTIRALPKQGISRGRARHRLAQKAKGRRRGQGSRKGTSRARRPKKEAWIQTIRPLR
                     ATLRQLRDEGTITRSVYREFYMKAKGGMFRSRNNLLMHLKTEGYLKGDN"
     gene            complement(136080..136730)
                     /locus_tag="PKM11_00805"
     CDS             complement(136080..136730)
                     /locus_tag="PKM11_00805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32e"
                     /protein_id="HNX47082.1"
                     /translation="MAAKKEINKIQDLPYYREEYTAQLADLGIKELDELLEALKDKDR
                     KKVIVDDLDGVGNKIADHWLELLSETEAETEIVDEEEKTVVKVKPVLNDEIKAALEFR
                     SAKNDARPAFKRQEWFRYQRLGEMWRKPRGIHSKMRRHLSYRPPVVSIGFRGPKMVRD
                     YHPSGFQEVMVYNPGQVEAVDPKVQAIRIGGTVGGKKRMAIIEKADELSIRVLNRT"
     gene            complement(136730..137278)
                     /locus_tag="PKM11_00810"
     CDS             complement(136730..137278)
                     /locus_tag="PKM11_00810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HNX47083.1"
                     /translation="MTVTGHLDDKVHVPKEVKVTMKGAEVTVKGPKGTVTRDFSHPKV
                     TVTFKGDHFHVECEYPRTKEKALVGTYASHLKNMVEGANHGFEYAMKMVYSHFPMKIA
                     VKGDRFIIENFLGEKAPRSAPILAGAKVSIKGAEVFVTGSDLEKVSQTAANIERATKI
                     RGFDPRVFQDGIYIVEKARRPK"
     gene            complement(137288..137677)
                     /locus_tag="PKM11_00815"
     CDS             complement(137288..137677)
                     /locus_tag="PKM11_00815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HNX47084.1"
                     /translation="MQSDPLNDAMSTIKNAAAVGKSECVIRPSSKLIGRVLKVMQDNG
                     YINQFEFIEDGKAGVFKVMLEGRINNCGVIKPRYSVKKVNMEQFEARYLPAQDFGVLI
                     LTTTDGVITHMEAKEKGVGGKLLAFVY"
     gene            complement(137688..137834)
                     /locus_tag="PKM11_00820"
     CDS             complement(137688..137834)
                     /locus_tag="PKM11_00820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HNX47085.1"
                     /translation="MKPKKKFGRSVGCTRCGRKRGIVRRYGMHLCRQCFREIAPQIGF
                     KKYS"
     gene            complement(137831..138346)
                     /locus_tag="PKM11_00825"
     CDS             complement(137831..138346)
                     /locus_tag="PKM11_00825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HNX47086.1"
                     /translation="MSENIMRLPRIEKVVVNMGVGESGDRLIKAQKVIEMVTGQKSKQ
                     TVSKVTNRDWGIREGQPIGCVVTLRGAKADDFLKRAFTIRENRIASYSFDREGNLSFG
                     VPDYTDFSGMKYDPEIGIFGMDISVSIQRPGKRVARRRVMRRSIPHTHRMTRPEAMEF
                     IKQKFNVEVID"
     gene            complement(138343..139053)
                     /locus_tag="PKM11_00830"
     CDS             complement(138343..139053)
                     /locus_tag="PKM11_00830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4e"
                     /protein_id="HNX47087.1"
                     /translation="MTQDLKRLNAPKSWPVTRKSHVWVTSPNPGPHSLDGCMPLSVVL
                     RDMLKVVDTAAEAKKVLSSKKVLVDGKVITEEKFPVGLMDVVSIPANGKHYRMLLDDR
                     GKFILVEITEDRAKWKLCRIENKTYVSGGRLQLNLHDGRNMLVESDIYKTGDVLKIEL
                     PTQKVIEAFKLVQGNVAMIVSGANAGQINVVDEQIEERSTAPNLVRFKNGKLTVKDNV
                     FVIGNKTPEVVLPEVRAV"
     gene            complement(139050..139421)
                     /gene="rplX"
                     /locus_tag="PKM11_00835"
     CDS             complement(139050..139421)
                     /gene="rplX"
                     /locus_tag="PKM11_00835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HNX47088.1"
                     /translation="MTSKHARKQRKALFNAPNHVRNKSVGSHLSEELIKKLGRRTVRV
                     VKGDTVRVVRGDEDILGSEGKVTSVDTHNGKLIVEGVTIAKADGTMTERPVHASNVVV
                     TKLDLKDNYRKQKLQYEEGSQ"
     gene            complement(139432..139830)
                     /locus_tag="PKM11_00840"
     CDS             complement(139432..139830)
                     /locus_tag="PKM11_00840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HNX47089.1"
                     /translation="MKGLAGNQTRGIITGSHLDVVDNTGAKVISVIAVPNYHGVHGRC
                     PAAAVGDIVVASVKKGTPEMRRQVVYAIIVRQRRPFRRADGTMVHFEDNAAVITTEEG
                     ETKGSDIKGPVAREAAERWPRVAATASTIV"
     gene            complement(139835..140161)
                     /locus_tag="PKM11_00845"
     CDS             complement(139835..140161)
                     /locus_tag="PKM11_00845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HNX47090.1"
                     /translation="MSEVRDIGIDVKAPSATCEDKHCPFHGQLPVRGQIIDGVIVSVK
                     MNGSAVVERNYLKYDKKYERFEKRTRRYTAHNPPCLEIAAGDKVRIMECRPLSKTVSF
                     VVVEKR"
     gene            complement(140166..140408)
                     /locus_tag="PKM11_00850"
     CDS             complement(140166..140408)
                     /locus_tag="PKM11_00850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein subunit"
                     /protein_id="HNX47091.1"
                     /translation="MRQEFIGLDIEVVESSCPGHLLHGKVVDETKNMFAISCQGRERW
                     IPKSGHEFVFTYQGERIRVLGSEIQHRPEDRIKRIR"
     gene            complement(140432..140731)
                     /gene="yciH"
                     /locus_tag="PKM11_00855"
     CDS             complement(140432..140731)
                     /gene="yciH"
                     /locus_tag="PKM11_00855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015492826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HNX47092.1"
                     /translation="MADICSVCGLPKELCMCEEIAREQQSVRIYTDSRRYGKIVTVVD
                     GIDSTDIDIDDLARKLKNKCAAGGTAKEGKIELQGDHKKKVAQTLEEMGFKTEVR"
     gene            complement(140731..140931)
                     /gene="rpmC"
                     /locus_tag="PKM11_00860"
     CDS             complement(140731..140931)
                     /gene="rpmC"
                     /locus_tag="PKM11_00860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HNX47093.1"
                     /translation="MALLRTSEIREMSVDERAAKLRELQDELMHEKGAAAMGGAPNNP
                     GKIRALRSNIARILTVQKEEEQ"
     gene            complement(140932..141657)
                     /locus_tag="PKM11_00865"
     CDS             complement(140932..141657)
                     /locus_tag="PKM11_00865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HNX47094.1"
                     /translation="MASERKFTQENIRRVLLKEHLMRTVDRAGFGGVEVQRTPMGTRV
                     SLVVERPGIVIGRRGAAIKTLTKDIEDKFHYDNPQIEVQEVENPNLNAQIMAEKLAFA
                     LERGWHFRRAGHSTVRRIMESGARGCLIIISGKLTGERHRTEKFKEGSIKYCGETRNL
                     FIGTGFAVAKLKPGVIGVQVEIMQPGAHLPAEIDVMPMEMAMQANPDLVDLLKKLEEA
                     SVIAEHPAEDEAPAESDKKEVTE"
     gene            complement(141658..142104)
                     /locus_tag="PKM11_00870"
     CDS             complement(141658..142104)
                     /locus_tag="PKM11_00870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HNX47095.1"
                     /translation="MVGYTSEADPDTTSKAIAKELPISPKFSREICRMIRGKKVDVAI
                     QMLEEVVELRRPVPIRRHNFGVAHKTGVGPGRFPKKAAAAIIRVLQSAKSNAEYKGLD
                     ADNMRVRIVSAHLGRTIPGYMPRAHGRSTAWNQQTVNIEVILEEVQ"
     gene            complement(142115..142576)
                     /locus_tag="PKM11_00875"
     CDS             complement(142115..142576)
                     /locus_tag="PKM11_00875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HNX47096.1"
                     /translation="MAEDKLTGTKASRRKQRKKKGMMTARRKKEFTYRGFTMEQLLEM
                     PFEEMVDLLPSRVRRSFRRGLNEEQKTTYDKIVDGEQEVVRTHRRDIPIVPSFVGRRV
                     AVYNGKEFKEVEIKPEMIGHFLGEFAMTRGSVKHSGPGVGATRGSKFMPLK"
     gene            complement(142583..143281)
                     /locus_tag="PKM11_00880"
     CDS             complement(142583..143281)
                     /locus_tag="PKM11_00880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HNX47097.1"
                     /translation="MGRQLRQQRRGRGTMTYTSPSHRHVGEIKHPYVELKTGKVTDII
                     HAPGRNSPVAEVQFEDGKKEKIIAVEGLMVGQDISVDGSLSLTPGSIMPLANIPEGTL
                     IYNLEARPGDGGKFVRTAGNYATVVTKGDTVLVQLPSGAFKNFDPRCRAGVGIVAGGG
                     ASEKPFAKAGKKFHAYRSKSKAYFKVKGVAMNAVDHPHGGGGHPHVGKPSTVSRNAPP
                     GRKVGRLSPQKKRK"
     gene            complement(143293..143571)
                     /gene="rplW"
                     /locus_tag="PKM11_00885"
     CDS             complement(143293..143571)
                     /gene="rplW"
                     /locus_tag="PKM11_00885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HNX47098.1"
                     /translation="MARKVLLYPYVTEKTMNYMTGTPTQDFKDGNKIEFIVDRFASKA
                     EIKSAFETHFEVKVDKVWTKISKDGKHAIFKLAEGYSAEDIGMRIGVF"
     gene            complement(143574..144338)
                     /gene="rpl4p"
                     /locus_tag="PKM11_00890"
     CDS             complement(143574..144338)
                     /gene="rpl4p"
                     /locus_tag="PKM11_00890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HNX47099.1"
                     /translation="MSKVNVYSMNGEVLRTEALPEVFSTEFRPDVIHRAVVAEESNKR
                     QPYGPKPGAGIRHSVSTWGKGRGVARVQRLSSGSKGAESPNNVGGRRAHPPRVEKVWT
                     MKVNQKEKTLAKFSALAATADEEKVRARGHRFNEGLTLPVVIEDRMEDVKSTSEVLDV
                     LKSIGVSDDVIRAKDGIRIRPGRGKMRGRPYRMPRSLLIVVSTKDAAVIKGARNLAGV
                     EVAFADMLNPGTLAPGGLPGRLTVFTEAAIKKIGEW"
     gene            complement(144342..145343)
                     /locus_tag="PKM11_00895"
     CDS             complement(144342..145343)
                     /locus_tag="PKM11_00895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HNX47100.1"
                     /translation="MSNIRRPRRGSKGFGPRKRAITQTPRLDSWPDISEGPKVQGFAG
                     YKAGMTHAFIVDRRKTSTTSGQEIRVPVTVLEVPPMKVAAVRIYENTRYGLKTAGEIW
                     ATQLDETLSRLLPIPKKVDADAVWEKLKGVDTEDVRVLAFTQPKLVTGVPKKRPELME
                     LRIGGGTMDARVDFAKGLLGKDIAITDFANTGAMIDVVAITKGKGFQGATKRWGLKLM
                     SHKNSKHRRAIGNLGPKRPGYVRTTVPQSGQMGYHQRTEVNKLILKVGESGQEINPKG
                     GFLHYGEVRNPFVLVHGSVPGPTKRLIRMRDPVRRQKPDLKEAPEMVYISTESKQGA"
     gene            complement(145616..145936)
                     /locus_tag="PKM11_00900"
     CDS             complement(145616..145936)
                     /locus_tag="PKM11_00900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5611 family protein"
                     /protein_id="HNX47101.1"
                     /translation="MDYDIKKGNYGKLEGDGLKKIMEASFGSVKVEGDVLISSYGAMT
                     RIEVRIVSKTSMDISATSDKNASPDLAADTIKKWNEFLEKATGFSSKERRNRLQKKAK
                     EGKL"
     gene            complement(145947..146933)
                     /locus_tag="PKM11_00905"
     CDS             complement(145947..146933)
                     /locus_tag="PKM11_00905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archaeosine biosynthesis radical SAM protein
                     RaSEA"
                     /protein_id="HNX47102.1"
                     /translation="MKSMDLNRPVTVWKEEDVVDGRKEKALVAIFRTRGCHWSRTGGC
                     SMCGYNVESLEGIGPEEISAQLSAILERYEGEGMVKLYTSGSFLDPNEIPLVVRDRIL
                     NAFDGARRVLFESRPEFVTPEVLKDLPDHSAVALGLESANDTVLRCSVRKGFGVKDYV
                     RAADALNDRGLPVRTYLLLKPPYLTERAAIEDTKASVHFAAARSESISVNPLNVQKET
                     AVEGLWKRGDYRPPWIWSLFEVLKLRSEISGVRLFSSPSGPGTPRGVHNCPECDRRLL
                     DVLEKFNFEQDASLLDKHDCQCRREWASLLRTEDAMRTSVDVHRYLDDDLRL"
     gene            147045..148397
                     /locus_tag="PKM11_00910"
     CDS             147045..148397
                     /locus_tag="PKM11_00910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HNX47103.1"
                     /translation="MARKIVVIGGGAAGMTAASTARENGAGDITLITEDEHVAYSPCA
                     IPFVVEGTIKDFPSIVMHTPEYYRRERGIEVLVKTTVDRVDAEAKKVITKDGRSFDYD
                     SLVIATGGTVFVPSIEGRELHGVFPVRWISDGQAIVDWLPSTTQVVVAGAGVIGLEMA
                     VALRERGKDVSVIEMFDQVVPRIMDKDMAQLVQAHCEAQGIKFVLGSPCSCIEGDEKV
                     TGVTAGKTHIPCQMVIMATGVRANLRIPEQLGLEIGPLGAVRVSPSLQPYRKGRLVPD
                     IYLAGDVVMCQSAVLAGPTMSQLGSTAVRQGRVAGIRATGGNATFPGTASPYVSVIGG
                     LQVGGTGMSRSLAEYYGVRVVESMAKGSSRARYYPGGKDMTVKLLADAESGRLIGGQI
                     VGGEDVTGRVNWITAAILEGVTVASFVERMENAYCPPTSMVSDTVNVAAEKLARTLRG
                     "
     gene            148444..149502
                     /locus_tag="PKM11_00915"
     CDS             148444..149502
                     /locus_tag="PKM11_00915"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HNX47104.1"
                     /translation="MDVEERYALVARNTEEIITPEDLMEVLRNKDSPTGYIGFEPSGL
                     VHIGWMVTAQKVKDFVDAGFTFIVFLADWHAYINDKLGGNIDNIRICAEYMKDCFEAL
                     GLPREKVEYRLASEIMDDIDYWETVMKVGKASSLQRVKRAMTIMGRNEDEAEVDSSKT
                     MYPLMQAADLIFMDVDVAYAGLDQRRAHMLAREAAEKMGVKKAVAVHTPLLPGLKGGN
                     RMDPVSSKMSKSDPEGSLLIHDSIEDIKRKMGKAFCPPEAEGNPVLAICKYVIFQRTS
                     VMRFERPEKFGGDLEFKSYDELELTYLAGKLHPMDLKNGTAAALADILAPTREYFVRK
                     PENLERIRQVLSEVKKLR"
     gene            complement(149505..150449)
                     /locus_tag="PKM11_00920"
     CDS             complement(149505..150449)
                     /locus_tag="PKM11_00920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HNX47105.1"
                     /translation="MLDDIISRLSSSDKIILVHGNADPDALGSAYALAKAFPPADILP
                     VEGLDRTSKNVSARLGMELLTRPERSYPLIVVVDTSSPEQLGSYSQMQGEMIIIDHHC
                     PTNKWAERGTYLCDESKRSCAEVVLDIIDRAGRPLSKEMTLGLCAGILTDTGHFRFAN
                     PDSLRTFARLIEAAGVNMEDVLSLTDSPTDISERVAQMKGGQRMRFERVGGYIVAISQ
                     GSSFESSVCKSMLSLGADIAFVASQRDQEFRLSARARQDLVRKGLHLGQLLGDVGNET
                     DNDGGGHGGAAGLVGIGDAEAILNICLQKSMAFLRKLK"
     gene            complement(150521..150907)
                     /locus_tag="PKM11_00925"
     CDS             complement(150521..150907)
                     /locus_tag="PKM11_00925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prefoldin subunit beta"
                     /protein_id="HNX47106.1"
                     /translation="MDEMSPKLQNQIAQFQQLQQQLQTVMNQKIRMDAMLKEMEMTLE
                     ELKKVPAETTVFKSVGSLMIKVADTPALLKEIEDDKETTEIRVKSLDRQEKMLKEKFQ
                     SVQEQLNRALGAQQQGAPLKMDEDDN"
     gene            complement(150900..151142)
                     /locus_tag="PKM11_00930"
     CDS             complement(150900..151142)
                     /locus_tag="PKM11_00930"
                     /inference="COORDINATES: protein motif:HMM:NF020899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex subunit Pcc1"
                     /protein_id="HNX47107.1"
                     /translation="MFRATLAVSSPFASNVARAISPEAGREIPRTRAAVSASEGSMTL
                     TLDADDLSALRAALNSYIRWMSIAEKMSETVGENDG"
     gene            complement(151145..151282)
                     /locus_tag="PKM11_00935"
     CDS             complement(151145..151282)
                     /locus_tag="PKM11_00935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit P"
                     /protein_id="HNX47108.1"
                     /translation="MNYKCAQCEKTTRSNLNQVGIQCESCGSKLFYKERPNVKKVIKG
                     R"
     gene            complement(151288..151554)
                     /locus_tag="PKM11_00940"
     CDS             complement(151288..151554)
                     /locus_tag="PKM11_00940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L37ae"
                     /protein_id="HNX47109.1"
                     /translation="MAKRTVKAGSSGRYGARYGVVVRKLTRDIEKTQRSRFECPSCHH
                     VSVKRVASGIWACRHCEAKFAAACYSPRTREAVSKEILAAHAKE"
     gene            complement(151560..152333)
                     /gene="rrp42"
                     /locus_tag="PKM11_00945"
     CDS             complement(151560..152333)
                     /gene="rrp42"
                     /locus_tag="PKM11_00945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000178 - exosome (RNase complex)
                     [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exosome complex protein Rrp42"
                     /protein_id="HNX47110.1"
                     /translation="MARSIVSEIKRDHIHKLIADGKRVDGRAWDQVREISIQTNVVET
                     AEGSSRVKIGNTEVIVGVKMTVGEPFSDTPNKGVLSTNAELIPMASPSFESGPPDPES
                     IELSRVVDRGIRESQMIDLEKLCIEPGKKVWINFVDIYVLDFDGNLFDACSLGAVAAI
                     KSAIVPAKANGLGEDYPMPTTCTPISITSMQIENSLLVDPTLDEEKVATARLTVTTDD
                     NGDLRAMQKGLTGALTLEQVKTAIETSRRLGIEIRKLIG"
     gene            complement(152336..153115)
                     /gene="rrp41"
                     /locus_tag="PKM11_00950"
     CDS             complement(152336..153115)
                     /gene="rrp41"
                     /locus_tag="PKM11_00950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosome complex exonuclease Rrp41"
                     /protein_id="HNX47111.1"
                     /translation="MGGNSDMKLIDENGIRIDGRKVDELRPMKIEAGVLKSADGSAYV
                     EIGKNKVLAAVYGPRECHPRHMQNPAKAIVQCKYNMISFSVSDRKRPGPDRRSVEISK
                     LISEAMEYVVFTENYPRTSIDVYIEVLQANAGTRCAGLVAAAVALADAGIPMKDLVPA
                     VAVGKVNDQVVLDLNKEEDNYGQADLPIAMIPRTGEVLLMQMDGHLTQAEFDQALEMG
                     VKACHEIYALQKDALRRRYAIVNGEAEEEPKEPAEDVIEEA"
     gene            complement(153126..153809)
                     /gene="rrp4"
                     /locus_tag="PKM11_00955"
     CDS             complement(153126..153809)
                     /gene="rrp4"
                     /locus_tag="PKM11_00955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000178 - exosome (RNase complex)
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exosome complex RNA-binding protein Rrp4"
                     /protein_id="HNX47112.1"
                     /translation="MNNESMTRELVLPGDLLDDGTMKPGEGTFVSDGKIFAAMLGIKS
                     VKSNFVNVIPLGGRYIPAPGDMIIGKVIDIGPSNWLVDIFSPYPAPLHVNEVPWRVEF
                     GDTARYLSVGDTLLAKVLSVDETKRVQVTMKEQGLRKLQGGQIVEISHSKVPRVIGKN
                     GSMIQMIKTYTNCRIFIGQNGRIWMDGNMEDMVHAMQAIKMIDEGAQTLKLTERVKEF
                     LESVYRKEE"
     gene            complement(153835..154533)
                     /locus_tag="PKM11_00960"
     CDS             complement(153835..154533)
                     /locus_tag="PKM11_00960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly factor SBDS"
                     /protein_id="HNX47113.1"
                     /translation="MVDLDEAIVARLESHGETFEVLIDPKVVNHLKEGKEVELIDYMV
                     IDEIFKNAHKGTRASEDKLKEVFGTLDAAEIAKVIIIKGEVQLTAQQRKEMLESKRLR
                     IIATIARNAINPQTGGPHTPARIEMAMEEAKVHIDAFKPVDVQVQQVMDKLRPLIPIR
                     FDTVRIAVKLKADEYGRCYDDMKEMGKITNEEWQKNGDWIGVVEIPAGLRDDLFHRLN
                     AKTHGEVETKQLKK"
     gene            complement(154546..155268)
                     /gene="psmA"
                     /locus_tag="PKM11_00965"
     CDS             complement(154546..155268)
                     /gene="psmA"
                     /locus_tag="PKM11_00965"
                     /EC_number="3.4.25.1"
                     /inference="COORDINATES: protein motif:HMM:NF003075.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000502 - proteasome complex [Evidence
                     IEA];
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaeal proteasome endopeptidase complex
                     subunit alpha"
                     /protein_id="HNX47114.1"
                     /translation="MQPGQMAYDRAITVFSPDGRLFQVEYAREAVKRGTTTVGLKFKD
                     GVVLIVDKRIASRLMEPKSIEKIFQIDHHIGCATSGLVADARILVDQARVLAQINKIT
                     YDERAGVEDLVKRICDYKQNYTQYGGVRPFGTALLVAGVDDQGEHLFETDPSGALVSY
                     KAGSIGAGRNVVMEVFEEDYQEGMSMEDAVTLGLKALKKATEEEKLNPKAVEIGVVRH
                     GENFRRLDDSEVETFIAKVNQE"
     gene            complement(155364..155672)
                     /locus_tag="PKM11_00970"
     CDS             complement(155364..155672)
                     /locus_tag="PKM11_00970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47115.1"
                     /translation="MVVKEKRGRRRYIAFRVDGKLSDEQLLAKLNATLSPKGIKVPKV
                     IQFDGRMGILRCSPLDKEKVVSLLAERSDPQGMIETLSTSGTLLTLRQKYFAETETRG
                     "
     gene            complement(155682..156749)
                     /gene="ftsZ"
                     /locus_tag="PKM11_00975"
     CDS             complement(155682..156749)
                     /gene="ftsZ"
                     /locus_tag="PKM11_00975"
                     /inference="COORDINATES: protein motif:HMM:TIGR00065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HNX47116.1"
                     /translation="MGAISPLFDDMFQKEAEQPMISSSADDDELRALVESLKIKIAII
                     GCGGGGSNTVRRMYQAGVDGVKLVACNTDARHLLSIQAHHKILMGRSMTKGLGSGSLP
                     EVGQKAAEESENDLWKYVDGQNIVFVVAGMGGGTGTGSAPVVADLAKRAGALTIGVVT
                     LPFKAEGAVRMANAIKGLEHLKEKCDTTIVLQNDRLLELVPKLPLEAAFRVTDEVLMQ
                     SIKGITDALTKPGLINIDFNDLLTIMRNGGMALIGLGESSEYGQRAEMCIEDALSSPM
                     LGDVDLKQAKGALVRVIGGEDLTVTEAEKAALLVSERIDPRARIIWGCAVHGDIKNEM
                     RVLVVLTGVKFNSIVESFKSR"
     gene            complement(156816..>157563)
                     /locus_tag="PKM11_00980"
     CDS             complement(156816..>157563)
                     /locus_tag="PKM11_00980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47117.1"
                     /translation="SMTDFNNQGATDLLGKVVRPKVLLTLFLGSLGLSSLTPIYYIIT
                     RRGRNGGKGWTFHEDRIDPLSPPEPRVKIRPVRGEGLICQICMGKLKHGLPHVKCDCG
                     KIFHITCLKRTEFCPYCQRTYTPEQVEQIAIYPEMECIKCPMCERMVYKDSGTCECGA
                     IISDEDGMFYCPVCGTQIREGENECPYCHERFEDIRLVICPFCGREFDANRGKCECGT
                     FLGEICPECGVRLTPEDDRCSSCGTVFETV"
BASE COUNT        31769 a        46509 c        45232 g        33853 t
ORIGIN      
        1 cgctcctgca catgggtata atgctgcctg gaaaggtccc gggcaaggtc agctacgaga
       61 acttcgccat aatctacatc ttcgccctgt gggtgttcac cttcgtcagc atagccacgc
      121 atttcgtgtg cctcgctctc ggactggcgt ccccggggct actggtcatg atcaccctcg
      181 gtctggtggc cggtctggtc accgtcaccg tgctgaactt cctttcctac tacgtcgcgg
      241 tgaccacctt catgttctcg ctagacccgg acgaccacag cattcccatc acctcgtcgg
      301 ccatcgattt catcggatcg ctggcgctca tggcggccat agtgatgttc ggtctatcca
      361 tctgattcgg cacaagttaa tattctatgg aacgttccct aattattcct gagggagctt
      421 gatgatcgac agggacacca tcttgggcaa actggaagct tacgatccgg agaagatcaa
      481 gatcggggtg ctcgcctcgc actccgcgtt ggacgtatgt gatggggcgg tggaggaggg
      541 gttccgcacc ctggccgtgt gccaggaggg ccgcgattcc gcttacacca agtacttcaa
      601 ggcctatcgc gagaaggacg gtaggttgag aaggggaata gtcgacgaga ccttgatgct
      661 caagaagttc aaggacgcta cgagccaaaa ggtggtcgac cgcctgctga aggagaacgt
      721 cctcttcgtt ccgaaccggt ctttcacatc ctattgtggc gtagactcgg tggagaacga
      781 tttcaccgtt cccctggtcg gttcccgtaa cctgctgcgc tgcgaggacc gcggcggcga
      841 gaaggattat tactgggttc tggaacaggc cggaatgccc tccccgcgca aggtcaagag
      901 accggaggac atcgacgcgc tgaccatcgt caagctccat cacaaacaga agaagctgga
      961 gcggggattc ttcaccgcct ccactcccga ggagtattgg gagaaggccc ggaagctcat
     1021 cgccgacggc gtgatcgagg aagaatcgtt gggcgaagcc cgcatggagg agtacatcat
     1081 cggtccggtg ttcaatctgg acttcttcta ttctccttta gaggaaaagg gttctcgcat
     1141 cgagctgctg ggtatagact ggcgcttcga gtcctccctg gacggtttcg tccgattgcc
     1201 ggcggaacag cagctggcct tgaacgacaa gcagcgcatt ccggagatga cggtgtgcgg
     1261 tcacaactcc tccaccatgc gcgagtcgct tctggacggg gcgttcgagc tggccgagaa
     1321 gttcgttaga acggctgaga agcacttcgc tcccggcatg atcggtccgt tctgcctgca
     1381 gacctgcgtg gacaaggacc tgaagttctt catttacgac gtagcgccgc gcatcggtgg
     1441 cggcacgaac gtgcacatgt ccgtcggtca cccgtacgcc aattctctgt ggcgccagag
     1501 cgtcagcacc ggaaggcgtt tggccatgga ggtccgcagg gcaattgtgc aggagcgcgt
     1561 ggcggagatc gttacctgag cgatgcttcg caaacctctt ttatatcttc tttgtagtag
     1621 gtgccagtat tgatttttca tttggataac ctttataaag agcaacacta ttccgagata
     1681 acccgagact cagtcagcac tgtaggtgcg cctatcgtga gggagggaaa taatgcaatc
     1741 gaataaaacc tggaagctag cgaccggatt gatggtcctg atgctcttgg ccatgccgct
     1801 cttggcggtc atgcccgcga acgttggtgc cgcaactact ggaaacaatc tatcgattat
     1861 cgtttatgat gagaacaccg ctaatcccgt agttggtgcc aaggtcaccc tgataggcgt
     1921 acaccagcag aacgccatct cccccaagac aactgggtcc gacgggctgg ccgtgttcac
     1981 cccctttgat ggatattaca tggtgactgt gactcacctc gggtactata cttatcagag
     2041 cgaaggggtc atccgattca ccgaccttgc cgcagacacg atctccatac ctatgaagat
     2101 gatgtccgct gacaagtata ctctgaccgt caacgtgaac ggtaccactg gccccctcaa
     2161 cggtgcctca gtggtcgtta agacggtcat tgacaacgtg accacctcga tctccgcgac
     2221 cgccgtcagc ggggtcgcta cactgcagct gcctaacggc acctactcaa tagtgtgctc
     2281 gaactccacc tacgctaccg acgtggagag caacgtggtc atagccggcg ctgccgtggt
     2341 caagaacata accctggccg cagccgtgaa gtacaacggc ctggtcaccc tggacggagc
     2401 tcccgccacc ggtgtcgtcg cctacctggt cggcgctgat cccctggtcg agactgaccg
     2461 taaggtcata aaggcctccg gtacctcacc gttcttcagc ttcgatgcct ttgtcggtaa
     2521 cttcaccctg ctcgtggacg ccaacggcgc cctggcagcg gtcgaggccg ttactgtggc
     2581 cgccagcaac ccgctcaaga acgtggtgct ttccaagcag agcgtgcaga ctgagaataa
     2641 ctccttcgcc ttcggggctt cggactggaa cgtggccacc ctgaccaaga ctatgctcct
     2701 ggaccatgac aacaccgttc ccggcctgga ctacgcttac ctgcccagcg ctaagatgca
     2761 gatcgatctg gtgttcggca acggcgatgg tgaagtgaac gccaccgagc tggccgcctt
     2821 cggggccaaa atggtcgagt tcggccccat cgacgtgacc accaccgaca tgatctcggt
     2881 caactccaag aatttcatat ctgacgttgc cgaccctggg tataccataa ctggtctgct
     2941 gggtccggtc aatgacacca gcaagttcca ggtcgagatg gtcgccgggt acaccagcat
     3001 tgaggccatc gccaatggtc tggccgcata taccgtcgtt gtcagctccc agaagaccct
     3061 ggccgacatg agctacacct acaaggccgc actcccctcc ctgtatgaga gggtcggtgc
     3121 cgccaccatc agcccggccg gctctggtgt gatcgtgacc ggttacacca atctaacggt
     3181 gacctccggg acctcctcgg ccaccgccac gatgaaggtg caaaagtccg cggcgcccac
     3241 cgccgcggcc gcgatagtca ccggcgtcaa cgcctacaag gtcatgaacg gttcgacctt
     3301 cctgtactac atagtggcaa agggcgagaa cgtgaccttc accgcctccg gttcctccga
     3361 tcccaacgct aacccattga tctacaggtg ggactttggc gacggcaaca acagcggcga
     3421 gatctccaac ctcacctatg tgcacgctta cgccaacgct gagcagtaca ccgtcaactt
     3481 gaccgtgaag agccagtccg gactgcctgc ctataaatcc ttcaacgtga aggtggatgg
     3541 cgtcaacccg actgtggccg ccaagcagaa cgttgacgtg ctcggagcga ccctgaacat
     3601 cgatcagaac aaggcgtata ccttcaacag cgccgcttcc gctgacatgc tgaacgcgac
     3661 cgaggctggt ctgattcaca gctacaaatg ggtatggggc gatggcaaca ccaccaccgt
     3721 gctcatgggc gagaaccaga ccgtgaccaa gacctacgct aggtccggcg tgttcaccat
     3781 gtacctgaac gtaaccgacg tggccaacca caccaccagc aaggcggtca ccgtcaccgt
     3841 gaaggatacg gtaaagccaa ccgtgaagtt ctccgtcaag ctgaacacca ccgtggtcac
     3901 cagcgccaag gagttccaga acctgacctt tgacgcctcg gcatccagcg atgccagcgg
     3961 aatagccagc tacctctggg acttcggcga cggaaccaac agcaccctgg cctccccggt
     4021 gcacagctac tcggagatca agaccttcac cgtgaagctt accttgaccg acaacgccgg
     4081 gaatgtgggt aacaccacaa tgggcttcaa ggtcgagtcc tcggcccgtc cggacctccg
     4141 cgtcggcgcc gtgaccttcg accccaccaa gttcaccgag ggcgaggatg gatacatcta
     4201 cgtcaacgtg accaatgtgg gcaccgctcc ggctgagggc atatacggca agctgtacaa
     4261 ggtgaactcc gacggcacca ggaagctgct caccgatgtg agcgtcctgc tggtcaacga
     4321 caccaaggac actgaacttc aggtcggcga gaccggcgtg ctgaggttca aggtggcctt
     4381 cgactccaag ggcgagtaca ccttgcagat caacgtcagc gccaacgctg aggtcgcctc
     4441 caagatgacc gacaactccg ccaccaagtc cctgaccgtg gaggaagctg cctggaagtc
     4501 ctatctgctg tacggtggga tcttcgccgt gatcatcgta gtggtcgttc tcttcctgtt
     4561 ccggaagaag ctgcccatga tgtccggcaa gaagaaggaa gtcacccctc cggccaagaa
     4621 gaagtaggca aaacctttta ccatcccttt tctttttatt tatgaatgtt gcgccttgtt
     4681 gactcgggtc tctgccatcc cctttactcg gtcgcgatcg aggaagcact gctggaatcc
     4741 tgttccaaag gcctcatgcc acccaccttg catctttacg tccgtgatcg accgacggtc
     4801 tccctgggct atttcgagaa ggtggaaacg gccatcgatc cgcaggtgct tttggacgag
     4861 gatgtgttcc tagtgcgccg gatgtcaggc ggcagcacga tcttcaccga tcaaggtcaa
     4921 ctgatattct ccctgaccat cgatcagggc gccataccca acccggagga cgcctacgcg
     4981 ctcacctgcg gagtggtcgt gaatgccctg gaatcgttgg gggtcaaggc cgagcacaag
     5041 ctcccgaacg acatcctggt gaacggtaaa aagatatctg ggagcgccca gaccaggaag
     5101 aaagggatgc tcatggtgca cgggacgctg ctcgtcgaca ccgacctgga ccgcatgatg
     5161 cgcgtcctgc gtccgaagaa cgacaagcgc tcccgcaaca gggaacagat gacctgcctg
     5221 cgcgacgagc tcgatcgttc gccggacatg aaccaggtga aggacgctct ggtccaggcc
     5281 ttctcgaacg aactggagca gagagcggtc tgcataccgg tgaacgaaag ggagaaaggt
     5341 agggtgaagg ccctcatcga agaaaagtat ggaaaggagg atttcatcct ccagttctga
     5401 tcacttgaag ttttccaggt ccaggaaggc gaacttgcgg ccgtctatga agaaaccgac
     5461 cttcttgtgc agcatgaccg cgtccttggc gtccggcata accacgctct gcaccgcctt
     5521 ggcgcctttc ttcttgccgt ccagcgcagc gcggcgtagc aacttcagcc ccactccctc
     5581 gcggcggtgg tccgggtgta cacccaggtt ctcgatccac agcacctttt cgatgttgtt
     5641 cacgtactgt atgatctggg agaacaggaa tccgacgatc tgtttgttct ccacggcgac
     5701 atagctcatg ccgccctccc gatagtaatc gaaggagtcc ttggtggatg ctcccaactg
     5761 ctccatgagc tcggccggca ggtcgtccca gctcttctgc agggaacctt ccaagtactc
     5821 gcggatgcag aatagctcca gcgtcctcac ttgcggttta tcctcgtcct tgagcttcct
     5881 tatgtccacc attacatctc ctccggagcc gctatcccca tggtcaccaa ggtgtttcgc
     5941 aatgcccacc gggccgcctc caccaggcat agcctggcat cctggtgctc cgacctgagc
     6001 accgggaccg cgccgtagaa ctggttcagg gccgaggcca gctcgtgacc gtaggtgggg
     6061 agcatgttta tgcggcgttt gtcccccgcc tgccgaacca cttccgggaa ctgcgccagt
     6121 atccatacga gcctgcgctc ggatgggtct gtcaagaccg atacgtcagc gcttttatta
     6181 aaatctcccg tcttacgaag tatggaacag catctcgcat gggaatactg aacgaagggg
     6241 gcgctgtttc cctcgaagtt caaagcctcc tcccacttga atatgagctg cttttccgcc
     6301 tgaacgcgaa tgatgttgta gcgcaccgcg ccaacaccga tatcgcgggc tatgctgcgc
     6361 ttcttctcct cgtccagatc ggggcggcga gtgctcactt ccttgtaagc ccgttccacc
     6421 gcctcctcca gcaggtcgtc cagatagacg accacgccct tgcgggtgga catgcgccct
     6481 tctggcaagg aaacgaacga gtagtagatg cactccggtg accgatcgag gccgagtatc
     6541 ttcagggccg aggccagctg cttctgtccc agcttctggt cctcgcccag gatgttcatc
     6601 agctcctcgg cccgtttgaa cttgtccatg tgatacgcca ggtcacgggt ggtgtacagc
     6661 gtcgtaccgt ccttgcgggt gaagaagaaa cgggtatcgc gtccgtgcac cccgaactcc
     6721 tccagattta gatagtaagc tccgtcgtcg atctcggagt aactggacgc cttaagtttg
     6781 tcgaccactt cgcgcgccga cccgtccagg atgaactgcg attcgtatgt gtagcggtcc
     6841 aggaatacgc ctatcccggc caggctctcc ttgatgccct caagcatcag gtccaccgtt
     6901 cggcggacct gggcgatgac ctcggggtcg cccgcctcga acctctgggt catgaccgcc
     6961 acgtcgttgg cgacctccgc cgacgattcc atcatcttgt tggcggtctg gtaatatccg
     7021 accaggcgat agtcgttctt gtcccggtcc cagggtggca cgtccttctc ggtgaggtgc
     7081 gccagggccc aggttaggag caccacttgc tttccgacgt cgttgacgta gtattcggtt
     7141 ctgacgtcgt gaccgcacat ccgcaggcac ctggccagag tgtccccgat caacgggttc
     7201 ctggctcggc cgacatgtat cggtccggtg gggttcaccg aggtgtgctc cagcagcaac
     7261 cttcccggcc gggggtctcc cttgccgaac tcctcccggc gctgcatggc gtcccttatg
     7321 accagctcgc tcagcagcgt ttcgttcacc cggaagttga tgtaaccctt atcggcccag
     7381 accttgccga tcttatcgtc ggtggtgatc agggcgccaa gttcctgagc gatcgccggc
     7441 ggcgccttgc gcagctgctt ggcaaactga aagcagggca gggccagatc ggccatctca
     7501 tggtccggcc tttcgagaac gatctcgccg gtgaatccca tgacgctgag ctccgcggat
     7561 aatttggaaa tgatatgctt ctcgaaatga cccaaggcgt ccatttaccc acctatgctg
     7621 aacctgagca gtccggctat gcctccgaag gccttcaaga gcatctcccc ctcttccgag
     7681 tccggggaga tgagctcgac cttggtgccc atcataccgg cctggtcgaa cagatcgtcc
     7741 accaggtcca cgtccttggt cacggtgccg acggtcccgc acttgggaca ggtcatgacg
     7801 gtaccttccg ggctcttgtc gatagtaagt tccaaggtcc cgcactgcgg gcaatccaag
     7861 gtcacccggc gtttgcgaat cccctccgat accagcagca cgtccaccgc cccgatcatg
     7921 atggcgttgc gtatctggtc ctcgccgtac acggacaggc cgccctcgga cttccggatc
     7981 tcgttgagga actgctggaa caaacgcttc tccctcatca ggtccaggtc gtacagcttg
     8041 tccttggcct tctccaccag ctccttcagg ccgtactcgt ccgtatagcc gatatcgaag
     8101 gtgtcgacca ccttcttggc cagctcgtga tggaggtaac cttccttgat gaagaactcc
     8161 ttggaaggcc ccggtccacc gaccagaatt ccctgcaatc cgtcaatgcc gaggaacgac
     8221 tcggtcatga tgtcgctgac cttcttgtaa tactcgttgg cggagatctc gatgagccgc
     8281 tcgaaacgct gtgccgactg tccgcccatg cggtgcttgg acggcaccag ggagtccagg
     8341 ttgcggatga cgtggatggc cttgccgcga agcacgccca ccgtggcctc gcttcggtca
     8401 attaccacca ggccgtagac cttcttgtct agcagcattc cttccaatgg ctccaggtag
     8461 aaatcggagt cgcatcggta caggaaggtg gtgatggggt cagggggctc cagcacatac
     8521 tggaccatcc tggtctggtc gccggtggcg gatatctcgc cgacgaagaa gatgacgccg
     8581 ttggccggag gggtcttgaa gtacttcagg cgggccagga tcgaagagat ggctccctgg
     8641 acgttcttgc gggtgctcgc cgatttaatg ttggaggact gggagaactc ctcgcgcaga
     8701 taggcggcca cgtcggagat ctgcttggta ggcggcacgt aaactgagat gagctcagtt
     8761 cctcggccct tcaagttcct gatctcctcc agggacctct tgaaatcgta cttctgacga
     8821 tcggagaggg tctcgccggt tattccatcc atattccaac gacctatcct ttttttaggt
     8881 gaaaacggtt cacacttata tctgttggta tgcaaatgga caagatagtg gtttccctcg
     8941 gcggatcggt catcgtgcca gatgataacg atgatgcctt tctgaagcga ttctccgaga
     9001 tgatatcttc cctctgcgac cggtatcaga tatacctcgt gtgcggcggc gggaagatcg
     9061 cccgctacta catcaaggtc ggtcggagcc tggggctaac ggaatacgac ctggatgaga
     9121 tgggtatact atcaacccgc atcaacgccg ccttggtggc ctattcgctc ggcgacattt
     9181 ccgtcggaaa ggtgcccacg gacatcctgg aagcccaccg gctggagaaa aagggaaagg
     9241 tggtggtgat gggtggtacg gtcccggggc acaccaccga tgccgtctcg gctatgttgg
     9301 ccaaagaggt gaaggcggtg cgcataatta acggtacgtc ggtcgacgcg gcgtacaccg
     9361 ccgaccccaa aaaggaccct cacgcggaac gattgtcaaa gatcacgcat cagcagctct
     9421 acgaactggt gaacgtggga atgcacgggg ccgggccttc caacgtgttc gatagattgg
     9481 gggcgcagat cgcccgggac ggtcatataa gcatcagcat cgtggacggt cgggacatcg
     9541 aggagatgag ggcggccatc gaaggccggc ctatcaaagg gacggtggtt tcagattagc
     9601 ctgttctcca aagaggatgc caaggccgga aagcagaagc gccctcccaa gaagagcgag
     9661 aggaaggctc cggtcgctcc ttccccttcc aagccccagt ccaatatgcc ccaggtccag
     9721 cacgacgcca tattggccgg tggggtgttc gccatcatcg gagggatcct catgctggtc
     9781 tcggcatttc tcccctggat aacgttcgag ggggagccgc tcatattcct ggaccttctc
     9841 agcctggacc cggtcttctc ggtgctcccg gcggcctcgg cggtcggagc atcgctggtg
     9901 ctgctgacct cggtcatcat ggtaaaggtg ttcgtttccc gaaagccgct gaaccggctt
     9961 cctttgtatc aggcgctgat ctccatggcc ggcgcgctac tggtcatcgc gacgttcctg
    10021 ttagcgcgcc aggagtatca ggggaccgac gccctgtacg gggcgggagc cttcaccgac
    10081 gtggtcgggg cgatactcct catggccggc tccatgctca tccatctgat gtccggacat
    10141 cgccgaaagc ccgccgccac cggtttcaaa gctctgtcgg agcgcagcgg ccaaccgtcg
    10201 ggaagaaatg agtggaatcc tccggagagc tcggtgaagg cgccaacctg tccgtcctgc
    10261 ggggaggagc tacggccggg ctggaaggcg tgtcccagtt gcggttacgc gctgctgtcc
    10321 gatgataggg agcgcggcag gctctgaagg tcctgtaggt cgcttccctc cagtacttcg
    10381 tatccggccg ataccagaag ctcattcaga cgcctagcct cgggacgtga gaatgatttc
    10441 ttgtgaatgt aggcgaacct ggtgcctgag gcgtttatcg cctttccgac gatctccagg
    10501 acctcggcgt ccgttctccc gtccagaaca tgcttggcca ccatatggcc gaagcgtacc
    10561 ttcttgacca gggtaacctc gctgaagcgc ggggcgtaat gccccccgcc gatgccgacg
    10621 accgtggggc cgtccgcggg aacatagttc agcagcgcct tcgccatggc ctgtgccgct
    10681 tccacgttat cccacttggt ctcgtcgctg cctatctcca cgtaggtggt cggaacgtca
    10741 aggaacggtc cgtggtgggt gacctcgtac gatatctcga agggcagccc cttggcgctc
    10801 gaggagagcg ctctcagcag tccgctcagg aacgccgggg acgctgggac cagcgagcct
    10861 tccttgcccc cgtagtcggc ctttccgaag ttcccgatgg ggtgcatggt cagtgtcggc
    10921 tttcccgagg ccgcccggtg cttggacagg aataccactt catcgatctc caaattgagc
    10981 gcctggccaa cctccttatc gacatggtcc agatgcaggt gcaaccgttc gatggagacc
    11041 atcagcatat tatgaagccg gtagtatggg cgtccctgat attctcctcc caaggaccac
    11101 tcggccactt ccagtaagcg gtctcgaagg ttgacgcttg ccggatcgag gaggctagcc
    11161 actagcagac gcataggacc gccaaccggc tcaggggata ttacggttac ggaggatgct
    11221 tgggcgacca tttctgatta tcaaaaacgc tacatgtaac cgtatgcagt ttaatgtcct
    11281 catcccttcg atgtttggat tgatatggct actcccatca cggtagggga aaggatcgtg
    11341 ctgcatctgg cccaatattc caagcattcg aacgatttcg acgccccctt cgaggtgagc
    11401 caagacggga tcggtgaggc cttgcgcata tcccgcgccc acgccgccat cgagctgaag
    11461 aagctcaagg aggcgggaac ggtgaccgaa cgaatagccc acatccgagc cggcccggtc
    11521 aagcgcaagg tctacttcct gagcgaggcg ggggagacca aggccaggaa cctcaaggac
    11581 ttcgccaacc gtcaggggat cgagatatct ccccttctgg acctcaagaa gtgcaagggt
    11641 gaggacctgt gggtgcagct gaactccgat tctcgttcgc tcatcgccaa ggccgcggtg
    11701 ttccgcaagc ctttcaagcg ttccgcgctc cctcagacca ccgtgagcct gctcccggag
    11761 gacaaggacg ggatggccga gctgccagaa cccctgcggg aatccatacc cgctcttttg
    11821 gacaagaacg ccttgcggga ggcccatagc ttcgccgccg actactggct taaagaaggg
    11881 gattacgtgg agaggctgca tcacctgatg cttgccaatc gaacgttgga ggcgcatatg
    11941 ctcctgtccg cccggggatg gcagatggcc cgctccgccg gaccggagat gttggcgtcg
    12001 ctcaaggaaa tgggtgaggt tccacctcgc tacgccaaag agatccgtcg cataaaaggt
    12061 caggccgcgc ttcgaaatgc cgatatcaag ttcggtcggc aggtagcgca ggagatgctg
    12121 ttgacgggcg atcccgagga gaccaccgat ggtctggagc tcaagggcag gaccctccta
    12181 ttggaaggca aggcccaggc ggccctggac gatctgctgg aagtgaaacg aacgaagccg
    12241 tcccctcttc tcgattgcga catcgctcaa tgctatggtc tgctcggccg taaggacgag
    12301 gccctccagt tgatggagtc gatcggccgc cgcggcggaa tagacgaccc agatgttctg
    12361 gaggaggtgt actatcgcaa aggtcaggta ctggcatcga tagaccgctc gcaggaggcc
    12421 atagccaact tcagtaaggc cctgggactg gcgaggccgg gcgataagcg cgcgatatac
    12481 aaggccacct catcctgcta cgagaagctg ggcatggagg acaaggcccg ggagtactcg
    12541 cgcaaggccc ttaaaagata gggctttgcc tgagcatgtc caggtccgtg acgtacagct
    12601 cccggatgtc cttgaggttc cacttcagca tggccaaccg ttcgaatccc aatccccagg
    12661 ccagcaccgg gtgctttatt cccagcggtc cggtgacctc cggtcggaag acgcccgctc
    12721 cgcccagctc catccaggan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt
    12841 caggctgttc cgcccttcct cgctcaggtg cagcatcggc tccgccccgg acttgtccag
    12901 gcgggccaac cgcttcttca tcaaccagcc gatggccatg gacgattcct ccttccccat
    12961 ggccgtctcc aggtccttga cgcccagcga gccgtccttg gcccctatga aagcaagggc
    13021 ccttctctct ggcactccct tttccaacaa ggagcggtcc ttcagggcgt aggccttgcg
    13081 agcgctctcc tcgatctcca ccgctccctt ggactgaagc caggaagagg cgttcatcac
    13141 ttccaccagt tgctggaagt cacccgcctc gaagaccttc tccggcgatg ccctgccctc
    13201 aagcttctgc agggccacca ggaccttctt ctcggaatgg ctgagacctt ccaacacctc
    13261 ggtggcgttc atgacctggg agatttggtc atcgatataa gttacttatg ggctcgtcga
    13321 acggacttcc ggcgagccat ccttctcatt tcctccgggt cccaggagaa tcctttgctc
    13381 atcactcctt tgatatccgc cacaggggtg tccacgaatg catccaggcc actcacccgg
    13441 agaacgttgc cattcctctc gagcagcgtc accctggtta ggccgatcgg actgggtcgg
    13501 cgagggcttc tggtcccgaa aagaccggtc agaggtatgt tcggatcgcc tctgggatgt
    13561 acctggaggt cgtatccctc gctgcgatcg aaaacaaaga ggacgtccag ctccttgagc
    13621 agctcgattc gatatagtcc atcggagaac tccgggaaga cctcgatctc cgagacgtcc
    13681 ccctctaccg atgacaccct tccaatgggg gtcagcaggt atcgggcagc aggaactcgt
    13741 ggaggcgctc cctggcctcc tccctcttcc tctgatgctc ttccaggaac tcgtttatcc
    13801 tctgggtcag cagctgcttg cactctccgc acagtatctc ccccttgtgg cacctttccg
    13861 tgaggtcgtc caaggccttg tcgtccttct cgaagaggta gtactggtac ttgaagaccg
    13921 agcagacctc ggggcggccg ccgagcttgc gttgctcttc gacggacacc tgccctccgg
    13981 tgaaggcgtt gccgatcttc ttcttgacct ccttcggttt gtcggtggtg aagatggtgg
    14041 tctgcggctg ggaggaggac atcttgtcgg aaccggtgag cccggggaac atcttgttgt
    14101 agatcagcgc cggttttgga tatcccaaca gtggcgccac atccctggcc acccggaagt
    14161 gggcgtcctg gtcgatgccg cagggtatga ggcaaggcgt cctctttccg tacagggcat
    14221 cctcgatgaa gcacggagcc gcttggatgc tggtgtagaa gatgctgccg atgttgtggc
    14281 tgttctcgaa gccgaacacg gccttggccg tggagaaggt cacacgcttg gcgaccttga
    14341 gcgccaacgg atagaggagc ttgatgtcct tggtgtccag gatgaccttg gtgttctccg
    14401 gttcgaatcc cagggcgatg aagtccagga cgttctcgta agcggccttc ctggtatctt
    14461 ccaggctgag gttctcgttg aagaggtact tctcgtcatc ggtgagctgg aagtacatgt
    14521 tgaccttgaa caggtcctgc aggtagcggt tgaacatcca gggcatgagg tggccgagat
    14581 gcgttccgcc ggaaggtccc cgtcccgtgt aaaggaagaa gcggttgccc ttatcgtact
    14641 ggtccagaag ccaatcgaag tcccggtgcg agtacaccac gcctcggcgg agcataggat
    14701 gcagctcacc ataaccagca agacggtcca gcagctcctg gtccatcttc ttggtcccga
    14761 agcgggttat gagctggtcg taatcgatct ccccggttac ttcccagggg gtgaccttga
    14821 agtcatcgtt catcgttccc agtggccagg aatggcgtac aggttcaaaa ggattattga
    14881 gccctctccg ccgaggtccg ggccagttcc ctcgctcggt tcaggaacct ggacagattc
    14941 gcggtaccgc aggggcggtt ctcgtggcgc aggccaagct cgtcggcgaa cttccgcgac
    15001 agttcctcat aatgctccgc atcgcccacg tcggtgtcga catagacgca cagctcgtag
    15061 ttctcgaaca gcatgtccag gaagtacttc ggctcgtatc cctggtccac cagggcgtcg
    15121 aggtgcagct ccttcaccgc cccctcgatc ccgcgcagcg cccagccggg ggtgttgaac
    15181 caggtcccga tgcacaggct cttctgccgg gcgtactcca ccggtcccag tatcgccgct
    15241 atgcagtcgt ccccttccag catcaccgac ggcaccttga ggtggttggt tatccccgat
    15301 agggactggc ataccgcata tcccaggaac accgcgtcca cctgcccctc cagggcgttc
    15361 accttgtcct ggaccgtcgc tttgagcttc tcggcgtcga tgtgcagggc gaactccaga
    15421 tagtccttgt gcaccacgtc gtcccagccc tcggtcagct tttccagctc gggcttgagt
    15481 atctcgcagg cgattatggc cagtcgtccc ttgccgttct ccatgggtga tcagctcctc
    15541 ttcggtaagg cgaacagacg tctcaagtat tccagcacag tgttccagtc cttgcagtcg
    15601 atgatggagt ctccgaccgg attatcgtcg tccagggtcc acatgtgctc cggggccgga
    15661 gaatcgtaat agatcagcat catgcggtaa ccccccttgt tcttcagatc gttcttgggg
    15721 ctggacacca ccgaggcgcc gtaatcgttc ggaaaccggt agatgttatg aaagcggtcc
    15781 ccgtccatgc acccgcaaac gcagtccgcg ttcagatcga tcacgtactc gtcgaactcc
    15841 aattcgcacc ccgttcccta tttaatcata tcttcaacgg acgaaatacg ttcatgccca
    15901 tcgaagcgat gctatacgaa cggcaatctc agtgatatta gcatcatctt caagaattgg
    15961 ctcggagcca ccctgatcac tcttacttcc gaaagctcgc tcatcgagaa cgaaaaagaa
    16021 ccatggagta gattatcata tcgtccgagg aacgattatc tatccccagc tgcgtatctc
    16081 ggccgatatg actctcaagg aagggctggt cgaggagatc gcctccatag ttggccgaga
    16141 gaactgctct accagcgtgg ccgatctcta cacctacggt ttcgattcat ctatccatca
    16201 ccacactccg gacgcggtcg ttcgtccggg aagcgtcgag gaggtatccc tcctggtgaa
    16261 gttagcatcc cgggaaggta tcccggtagt accccggggc ggagggaccg ggctctgtgg
    16321 agcggccgtt cccatcaaag gcggaatggt catggacctc acccgcatga accgggtcaa
    16381 ggaggtccgg gtgaacgacc tctactgcgt ggcggaagcg ggcgtggtat acgaccggct
    16441 gaacgaggcg ctgtcaccgt tcaagttctt cttcccacca acgccgggaa gtggcgaggc
    16501 ctgtaccatc ggcgggatgg tggccaccaa cgcttcgggg atgagggccg tgaagtacgg
    16561 cgccacccgg gactacgtgc tcgggctgga ggtggtactc gctgacgggt cgatcatcca
    16621 cgtcggcacc aacaccatca agaactcctc cggctaccag ctggagcgtt tgttcgtggg
    16681 gagcgaggga acgttgggca taattaccga ggtcaccttg aagatcgccc cccggccgaa
    16741 gaaggcggcg atggtcttgg cggccttcga ccgcctagag gacgctggca aatgtgtttc
    16801 caacatcatc tccgtgcctc tcatcccatc ggccaccgag ctgatggacg atatatgcat
    16861 ccgtgccgtc aacaaagcgg tcggggccgg ccttccggac gcccaggcca tatgcatgat
    16921 cgaggtggac ggggaaccgg agatggtggc caaggagctg aaggtggtgg aggaggtggc
    16981 tcgcaggagc ggcgcctcca gcgttcaggt ctcggacgac agcaagcaga tggccaaatg
    17041 gaccagcgcc cgcaagtccg tgatgtccgc cctcagccgc ctgggggatg atctggtctc
    17101 cgtttcgctg gccgatgata tggcggtccc catatccaag atccccgatg ccgtcgtagc
    17161 gttccaccgc atcgccgagg agaaccaggt gatcgtcggg acgtacggtc acgcggcgga
    17221 cggaaatctg cacaccaaga tgttgctcga tccttgctcg gaggattcct ggggtcgggg
    17281 cgaaagggcc gtcggccaaa tattcgacgt ggtgatctcc ctgggaggca ccgtcaccgg
    17341 ggagcacggg gtcggaatat ccaaagcgcc ctacatgatg agggagcgcc cggacgcctg
    17401 gcagaccatg ctgaccatca agaaggccct ggacccccag gacatactca atcccggaaa
    17461 gctcatgcag tgggagggcg ggatcatccg cgacctgcgc tatccttgcc gggacctatg
    17521 tctcagatga ggccatagcc gatcgccagg gggatggcgg tcacgatcac cgccaggacc
    17581 caggccgttg ggctccaggc cagcactttc ttgccgtcca acgggcctag cggtatcagg
    17641 ttgaaaccgg ccaggaacaa cgacagcacg cctatccagt tgaaggccgc cgaccacgtt
    17701 ccttcggacg ggaacgccag ccacaggatg atgaacgtcg ttccgaacag aatgttggtg
    17761 gacggccctg ccagggatat caacccgttc tgcttcttgc ttatccttcc ttgaatgtac
    17821 accgccccgg gggcggcgaa caggaatcct aagaaggaga ggatcaaggc catgaacagg
    17881 cccatcgggt acatacggta ctcggcccag gccccgtagc gctgagctac gaacttgtgc
    17941 cccatctcat gcaacaggaa tccggtcagg gacaccgccg cggccacccc gaaggcgaaa
    18001 taccatgggg agttgcccga tagcacgatg gtgaaggccg cggtcaggac cgccacgctg
    18061 atggcgatct gaacgagctc ttggcggccg aaatggaatc gaccaaagtc gcgtgggatc
    18121 accaggttcc cgtattcgtc gtacatttcg cacgtccact gtaccccctc gtttataaaa
    18181 gttgcccgcc cacgccgcag gataaggttg aagtacgtcc gcgcatcata gcttgcggaa
    18241 atgagaaatt accagcacgg caaggtcatc ttccggtggt gcgacagctg cggcaccctg
    18301 gtcctgggcg aggtctgcgg gatatgcggc cgccctggac gggagttcga ggtctccgca
    18361 ccgggggaca tccgcccatg tttcgggaag ggcgtggaca cggtggccga cctgttccaa
    18421 gggcacttcg gcacctccgc gttacttcgt accaggtccg tattcctgaa caaggtggcc
    18481 ggcgaggacc gcaccgacga ggtcatcctg gacgggagga tcgtggcggt catccgcttc
    18541 gagctggtta aggacgattt cagtctggag ctaaaggccg aaggggcagc gctcctggcc
    18601 aagatggccc gcaagggcgt gatcaaggcg cggcggccac agggtcatct aaagggcaag
    18661 aagctggacg gagccgacgt tctggagttc tctggcgagt tcaaggccgg cgacccggtg
    18721 gtggtcgtca tgggcaacaa catcgccgcc ggggaggccc gggtcgactc gtcccaggtc
    18781 aaggaaggag agaaggtcat ccacctgcgc agcgtgtgca aggcggacgt cccgttccca
    18841 ttggtctcgg cggactggaa cgatttcgtc aaggccaacg agaagcacct tagacagttg
    18901 gagtccaccg cggtcagtga catccgttcc ttcgtcaaca acaccaaact tccgataacg
    18961 ctatcctttt ccgggggcaa ggactccctg gcctgctacg gcatcaccaa gaaggccctc
    19021 cggaagttcg acctcctgtt cgtggacact ggcctggagt tcccggagac ggtacagtat
    19081 gtccaatcct tcgccaatgc caagggggag cgcctcaaga tcgctcgggc cggaaacgcc
    19141 ttctgggaca acgtcaaggc cttcggaccg ccggccaagg acttccgctg gtgctgtaag
    19201 gtgtgcaagc tcggtcccct gaccaatctg atcgaggaca actatcgaga tgggacggtc
    19261 accatcgagg ggaaccgggc gttggaatcc ttcgccagga tggatatcgg tttcgtggag
    19321 aggaacccgt tcgtgccgaa ccagaccgtg ctcaacccca tccgtcattg gatggccata
    19381 gaggtctggg gctacatctg gatggaggac ctggagttca accccctgta cgagcaggat
    19441 ttcgagcgta tcggctgcta cctgtgcgct tcctgcttag ggagcgagtg gaagtccacc
    19501 ggtgagatcc atcccgacct gcacgcgcaa tgggagtcca agctcgctga gtgggggaag
    19561 gcggtagggg tctctccgga gttcgtgcgc tacggcttct ggcgctggaa gtcgctgccg
    19621 cccaagatga ggctggtggc cgaggagctg cagatgaagg tgccccagat gaggaacgat
    19681 agcatggagc taagaatatc caaaggagcg agtccttgcg tggccggcgg tttctccatg
    19741 gagggcgtgc tgaccgtgcc gaggaacagg gatttctccc aggtggcgga agtgctcaag
    19801 accgtgggca aggtgaagtt ctccccggag ttcgaggtag ttatggtcaa gaccagggac
    19861 ggcaccttga agatgttcgg cggcgggcat atttcggcca tagctccgac caaggaaggc
    19921 gcccaggcgc tgttccgggc cggggcggag gccttcctgc gcggtcagct gtgcaccagt
    19981 tgccgcatat gcgagcgcaa ctgcaagttc aacgccatca cggccgacgg gcagctcaag
    20041 gtggacgatc gccgatgccg tcaatgcgga aaatgcgccc aggcctgcgt ggtagcacat
    20101 tactacgaca agttggtcaa ggccggagag ggtaaaccgg cctacgcagg cgttaaataa
    20161 tcgtaggaaa gtggagcgag acggacatga attggacgac tatgttggcc gcggcactgg
    20221 gcgtaggtcc ggccctggcc ctgatgttct ggaccctccg cgattacacc tatcccaagg
    20281 tggagaggcc tttcttcgac gatcgaaagc tgttcgggct tctggcggtg ggcatggtca
    20341 tcggggtggt ggtcttcgtc ctacaatcat acttcaacct gggttacatt ctgttcgccc
    20401 tgcttttcgc ggtgttcgag gaactaatta aattggtgat cctcaacatg ccgcgcttcg
    20461 ctcgcaagct agatacgtcg ttctacggcc tttcgctggg attggggata ggcagcacca
    20521 tggccttcgg ggtggtgttc tacaccattc agcaatctgg cgaactggac gccctaggtt
    20581 ggacgaccgt gatcattctc gctttccaga tggtcctcct tcacgcttcc gccggggcga
    20641 tgatcggcac cggctcggcc cgcggcgagg tcaagggcta tttcgctcag gccggtcttc
    20701 tgcacatcgg tttcaacctg ctcatggcca taccgctgaa ctttgacaac atctacctgg
    20761 cctgggtcgg cgtgatactg gccaccttgc tggtcgttta ctactatgcc caggtccacc
    20821 gccatctgct tccggccgtg atcaagggcg ccctgaaggc gatggaaagg gcgaaagcct
    20881 gatttagcca gagatcactg gaacgttcgt gtccgaagga aggcggaaag cgggcaagac
    20941 ccttctggtc gtggccgtcg tactggtcgt ggtgctcctg ctcttacttc cacccaccca
    21001 ggaccttctc cgtaaatatc tgctggaccc cttctctccg cagtatccag aggaggtcca
    21061 gatggagatc gttcggacga tgaccttgga tgccaacggg ggcgagataa ctggatacac
    21121 catcgacctg ccaaggccgg tcagcgtctt cgaggacggc acatatctcc agagggtgaa
    21181 ttctttcacc gtctcccgag cctatgatca tctttgggac aatggcacgt acgacaccat
    21241 ggtctgggaa ggggatgccc tgtacgacac gttcaccttg accatcacga tgaacgtcac
    21301 gcagaggatg caggtctgga agctcgacga ggagagcgtc ctggacaaga acgagatacc
    21361 tgagttctac cgggatagct atctcgatga ccagtggagg atagtggtca acgatccgga
    21421 gatcgaggcc ttgcgggacg atatcgtggg caacgagacc aatgtgtatc tcatcgccaa
    21481 ggccatctac gactggatcg acgagaactt ggactattat atctggccga gcacggacgg
    21541 tccgctatcg tccctggaca cctatgagaa gctcaagggc gattgcgacg accagtccat
    21601 attgttctgc gccctggccc gttcggccgg ggtcccagcc tggctgcagc taggggcggt
    21661 gtacgatcca gacagcggcg agctgggggg ccacgcctgg gtgcagatgt tcatgcccac
    21721 ggcggacgga ggaaagaacg tcaccatcga catcgtgaac aacaggttcc tggtctggat
    21781 gccgaacctt ttctgtgagt tcaccgataa tgggaaagcg gaagacctcc agaaggcgta
    21841 ttacacgacc tccatattct tcgatccttc gacctatggt cccactgaag gaccggtcag
    21901 agaggattct tggacggtgg tcagctacca ggagagcgag aggaccgtcg ccctgaactt
    21961 gatccttatc gccagagagg atttctaggc catccggtag cggccggggc cgcactcgta
    22021 aacgaaaccg gaggatacca ggcgtcgcag tgcctcctcg gcgttcatcc ggccgtccaa
    22081 ggccttctcg aggtcgtcca gatcgaaatc ctttagttcc gtggccaggt cctccaggga
    22141 ggatggcttg aaggggggcg ttctcttttt caataccagc ttcccttgga aacccttcgg
    22201 ctcccgaccc ttggtgttca gttcagcgac cgcctgggcg gtcagagatg cagaattaga
    22261 agtgaaatgg gttttcatcc ggcgggtctg caccgttcgg ccgcagtggg ggcaggtgga
    22321 ggagcgatgc tccaggtcca ccgcgaagcc cttccgacaa cgggggcaga ccacggctcc
    22381 gaacatcagt attctacgaa gaccaatgcg cccaggcagg ttccgtaatg gtccatgggt
    22441 atggacagct cctcgatggc gtagttgatg cggaggagct cgatgccacg cagggcggac
    22501 atctcggtca tcttccactc cagaacttcc ttcaaggcct tcttggtccc gtgcatgtgg
    22561 ccctcggcga cgtagccgcc cttgccatcc ttgcgctggg cgtaagctat cccggcagag
    22621 atcatctcgc cctcgccgcc cctcatctgg gccaggacgc agtgggtgat ggcgcccatg
    22681 ggcagctccc ttgcggccac cttcttggcg cctatgggaa gcacggagga tacggacacc
    22741 aggttctgct cgccgatctt ggctttcata agcgcctcat cgaaggcgtt gaggtcggag
    22801 accttgctca cggccgatcc ctgggtgacg aagaacttct tcgggactag attcataatg
    22861 tcgatgtaaa acagaatgtt gatataaggt ttgccttcag ccgatctcca agacccgcag
    22921 ctcgcgttcc agcatcttga cgtcctgggg gtttagcgct tctggcacga ccgggatgat
    22981 gagcatggag ctggtcgtgg acacattgtc attgagcagc tgcagaagtt tgagcacctt
    23041 caggaagttg ttctggctga tgagatactc caagcctgag agcagcacca ccgcccgact
    23101 gttcgcctcg aagaagttct tgatctcgct gtatatcatg gggatgtcgg tcggttcccg
    23161 ggcgtagcgc tttcctcttt cgtaggaaag ccacagtaat gccccatctc cgatgccata
    23221 cgtcttctgg accttctccg ggtactcgcg ggcaagcacc attccagtgc agccctccgc
    23281 cacctggtcc ttgtacatct gatacgcagc gtccaaggac gacgactcca ccaggtagga
    23341 cgttcctggt tccagcaggt acttccttcc cgattcgtcc ttgttcagag cgaccccctt
    23401 ctccgtcgga taggtggtag atggggtgag aacgtgaacg cactttaccg ccccgtcgga
    23461 tatgcaggac gcctcgtaag catcgtaacg acggcgcatt agcgaggaga ttattccgga
    23521 gaggtaaccg cgggtgaagt cgcaatggtc cccgttatcc gcttccaccg actccttgaa
    23581 ggtgatgacg atctccgtct cgttgatcat ctcgatgttc atccgggaaa ggccggtctc
    23641 catccatacc tgctcgatga tggccttggc atcctggatg tcagcgcatt ccagccctag
    23701 cgttcggacc aggcccaccc cggcccggaa gccgtagcgc tccatcgtcc gtccagcatc
    23761 gttcccgttc agtagctgaa gctcctccct gaggtctccc agggccgaac ccggcatgac
    23821 gaaaaagggc cgcatgtcct tgcccacgtc aaacctccat ggtaagctcg cctagggcct
    23881 ggaaggcttc ctggacgttc tgtccggtcc tggcgctggt cagcatgaat ttacagccaa
    23941 gcttgtcagc gaaagccttc aggtcctgaa ggtctatcgt catctccagg tcgcatttgt
    24001 ttcccagtat caggataggt atctttccgg atacctcgaa caggtcggcc gcccaattct
    24061 caagatgttc tagcgtttcc ggccgggtca tgtcacaaac cagcaacacg ccgttggcac
    24121 cgagataata ggtgttatgc aactccttct tcgtcttctg gcccagcacg tcccagatca
    24181 tgagggtgag attgacgtcc tccagctcca ggaccttctt gctgaccttg gctccgaagg
    24241 tctgtatgta ctgatcatca aattggtcca atacataacg tcggatgaga ctggtcttac
    24301 cgacctcccc gtcccctagg aggcagatct tcttgacgaa ctggcgctta gccatccagt
    24361 ccacagtatg ccgccggcgt ctatatattc atttcactag gtggggtttc gacctatcca
    24421 gtaacgacac accggatgtc attcgccgca atagtaatgt atctcgagcc caaattaccc
    24481 ggtatgccca agaccgagat gaggttcgag gacgtgctcg tggacgacgt cttcgacaag
    24541 ttcgtgctga agccttccca ggtggggaag ggcgccacca tcgccatggt catcgaccag
    24601 atgttggcca atccattatc ccgcaaggtc tacgtcaccg atgccgagaa caggtatatc
    24661 ggaacggtga gcacggagac ggtgctccgg ttgatgggtt accgactggg ggtgcgagag
    24721 tacggcggcg cctcgttcat tcgtttcctt aaggacaccc tcaaggaaag ggcggatgac
    24781 ataatggtca aggggcgtac cgtcaccagg gagacgaagc tgacggcggc catgaagata
    24841 atgatcgacg atcatctgaa cgacctgccg gtggtggaca atgaaggacg gctggtcgga
    24901 gagctggcca gcctacagct gctgatggcc ggaaagaagg ttttcgaggc caaggacccc
    24961 gccgtccccc cggtcaacga gtactagctc agccgtagag ctgggagtac tccaccggct
    25021 tcttcggctg ctgcaccgac tccatggcct tctgcatctc gctttcgatc agctcggcct
    25081 ccttgatcag cggctccggg tccaacttta tctccggtag catgtcgccg atcacgtcca
    25141 gaaggttggc cgcaccccgg gcgtccggaa cgtccgtgcg agcggaaccc agcaagcaga
    25201 tgacgtccat ctggtagcgc tccccttcgg aaaggagcag tccggagata ccggtgacca
    25261 ttccctcctt aagctccttg atcccatagg tcttgagcat ctcccgcgtg cgttccgtgg
    25321 ttcccactcc atagaccttg gtgtcgctct caccgaccat gttaatgccc tccagggtca
    25381 ggatggtggc tatccctttc ttcttgcacc atcccaggat gtcgtccgac agctccttga
    25441 tgagatcggg ctgaggcatg aactcgcagg tgatgacggc cagcttctca cacatttccc
    25501 ccttcacgca atcccgctgt ccagcgtaga tgcggaccgg gggcgaggga acgccctcat
    25561 ggatgatggt gaagggaggg aaatgtttgg agattatggc cgccctcctc tccaatttca
    25621 tggttcgaac gatatagttg gacgctatgg agctcaccag ccctacgctg gggaacccga
    25681 ccacgaccat tccgtccttc aggtcgacct cgtcatactc gtggatgaat atctcgccgt
    25741 cgctaatggg catcacctga ctttgaaggt aggtcagggg cttaatactt gacggtgccg
    25801 ccatcgaaag tccattatcc agggaaggcg ttccaggggc gtggtggaat ctggtttggg
    25861 tctgcatcgg accgcggcgg gcataccggt gatagtggag gaggtccccc actcccggac
    25921 ggccgcgctc tccgtcaact tcagcgtggg ctgccgggac gaggacaagg aaagctctgg
    25981 caccgcgcat ttcctggagc atatcatgtt caagggaacc aggaaacgca acgccaggca
    26041 gttctcggaa ctggtggagg gtgctggcgg ggagatgaac gcctacacca ccaaggagtc
    26101 cacgtccttc cacgttttct cgctggacga gacgttcgat gtgatgaaag gtctcatggc
    26161 ggacatgatg accgctcccc tgatggacga ggagcatgtg gacctggaac gaggggtggt
    26221 catgcaggag atcagcatgc tggaggacga tccagaggac tattcccggg tgcttctgga
    26281 ccgctcgatc tgggacgggc atcccatgtc caacaccgag accggccggc cggaatgggt
    26341 gtccagcttg aaggccgccg acctgcgcaa gttctttgag gaccattacc ggccgccgaa
    26401 cctatgcgtg gtggcctgcg gtcacgtgtc cgcagaggac gtggtctcct gggccgaaag
    26461 gacattcgac ggtctcagtc acgcaaagtc acagaaggtc cgcacgccgc cggttcccaa
    26521 ggcctacacc agggtcttcc cgaaagaggg ggaccaggcc tacgtggagc tggggttccc
    26581 agggctccca gggaagcacc tggaccgcaa ggcattgacc ctggcgtgca tcatactcgg
    26641 cggtggcaca tcgtcccggt tgtatcagac ggtcagggag gaccaggggc tggtgtatca
    26701 catcagcacc ttcccgcaat cctacaccga ctgcgggata gtggatacct tcttctcggc
    26761 ctccatcgac aacctggacc gggtggtcaa cactctggcc aaggagatat cccttttcaa
    26821 ggaccaggga cctacggagg aagaggtcca gaggtccaag cgctggatca aggggatgct
    26881 ggtccgtcgg cttgagggaa ccgacagccg actatactgg cagggcgaac attacatgat
    26941 gaacggcgag ctggccgatg ctgaacgctc catagccgag ttcgagaagg tgaaccgcga
    27001 ggacgtcacg cgggtcatca acgagatatt ccagagaaaa aagatgtgcg tggccatgct
    27061 cgctccccag aaggaagggg aggcggccgc caggcgtatg cagtccctcg acttctagtc
    27121 gttcaggacc ttcaggaccg cttccacggc ggcgggaacg gccttctcca catcctcggt
    27181 catgatgtca gtgacagtat agacgtcatt gacctccacc gccacgaacc ggatgtcctc
    27241 aggcattcgt cccgggaaga gcaacttacc cacctcgatg gccatgtgga tgttggtctc
    27301 gtgcgggttc gtcccgtgca gggcggtctt gaagtcctcg ggttccagca acatgaccgt
    27361 gccggccggg tacttctcgg tgatgatggc atcgaccacg accaccttct ggtagtccat
    27421 cattatctcg atgatgtcca gaccgctcac cgactgttga tccacgtcca ggtccggcag
    27481 gttccggttc ttgatctctt ccacgatccg gaagccaact ccatcatcgc agacgatggg
    27541 gctgccgatg cccagcaata aacgggacgc tttcatcgtt ctgccgaaga tggcggcggt
    27601 tattaacttt gccttttccg gctcgggacg gcggattaat ctaatccgta gttcatcgca
    27661 gcaccatgtc cttggtgcag gcctcgctca ccgtgcaggt caacggtcac gtcctgacgg
    27721 acaagcaggc caaggccgtt ctggcccttt atctgaaggg gacccagagg gccgcggccc
    27781 gttcgttagg gatatccgcc cccgtcctgt gccgtcatct ccgccaggtg gaggtcaagg
    27841 ctagcgcccc gattatggat tgcggtcccc ggggcacggt gctaaacgaa ctgggcgaaa
    27901 gcatcgccaa ggagcagctg gctctgcaaa gcaagctcag ggagcggcag cagctggcgg
    27961 tggcctgcac gcctctgacc gaggagctga tgatgcaggc cttgaacgtc gccgatccga
    28021 agggcgatat cgaagtggtg atatcggacg acacgcacaa cgtcaccgat ttccaggccg
    28081 gactgctgga cctggttctg ctggacgatc cgttgttcgc ctacgaggcg gagggggcga
    28141 gctgggagga ggtgggcagc gatcgtttgc tacatgtgcg caagggcgag gactacgcct
    28201 cttaccgctt cggaccgcaa aggctggggt tcaggtccct ggaggctcaa aaggtccctc
    28261 accgagtggt caggacctat tcttcgctcg gagctctggt tcgcagcggt catagctatt
    28321 tcgtcagcga ggggctgctg gtccgcaagg gctatcgtcc caagggggac gagcccgcga
    28381 tcccctacgc catactgtgc ctctaccgcc cggtccctaa ggtggacggg atactgaggg
    28441 caattcgtaa taaacccgtg aattagtgta acctatttag gtaacactcg tacggttttc
    28501 cgttcacttt tatataggat atctccgctc cccgagacaa gaggaagact ttcatgtcaa
    28561 acgtaaagat accagacccg gcctttaccc agagcatcat cgatgctggc ggtaagacct
    28621 tggacctgtg ctaccagtgc ggaacctgca ctggcagctg cccctccggc cgcaccaccg
    28681 cgttccgcac ccggcagctg atcaggaagg cccagctagg attgaaggac gacatactgc
    28741 cctccgagga gctgtggatg tgcaccacct gctactcctg cgtggagaga tgccccaggg
    28801 acgtcgatat cgtcgatatc atcatcctga tgaggaacat ggccgtccag aagggttaca
    28861 tggccgagga ccacaagaag gtcgggcgct ccctgataaa cagcgggcac accgtacctg
    28921 cttccgacaa gctgaagcat ctgcgcgtca gcatgggcct ctccgagaac ccgcctacca
    28981 ccatcgccga ccccaaggcc ctggccgatt tcaagaagat catggccaag accggattcg
    29041 acaagctgat cggaggtgct taaaatggcc gctgacaagt tcgcgttgtt cctcgggtgc
    29101 gttgcgcccc tgagataccc cggcatcgag aaggccacta gggagctgtt caaggccctg
    29161 ggttacgacc tgagggagat gaccggagcc ggctgctgcc cagcgccggg cgttatccgc
    29221 tccttcgacc aggccacctg gctggctctc gccgcccgca acctggccat cgccgagaag
    29281 caggactgcg acatactgac catctgcaac ggttgctatg gctccttgta tgaagcgaac
    29341 cacatgctcc aggaggaccc cgagctcctg aggaaggtca acgtcatcct gtccgaggtc
    29401 ggcatgaagt acgagggcaa ggtccgcgta cgccacttcg ctgacgtcct gttcaaggac
    29461 ataggcatcg agaagatgaa gcagaagttc accaagccat tgacctataa cgtggccgtg
    29521 cactacggat gccacttctc ccggccgacc aagatcaagc acatcgacga ccccgagagg
    29581 ccgcacgtgc tggatgagct ggtcgagtgg accggcgcca agagcatccc ctacgccgac
    29641 aagcagatgt gctgcggcgc cggcggcggt gtaaggagca gggacgccaa gttcgccttg
    29701 agcttcaccg aggctaagct gaagaacatg aaggcggtca aggcccagtt catcatcgac
    29761 gtctgcccgt tctgccacct gcagttcgac cgcggccaga aggacctgcc cggatatgac
    29821 ataccggtca tccacctggc gcagctctac ggcctcgctc tgggtctgcc cgtgtcctcc
    29881 ctgggactcg aggcccacga gatcaaggtc accctgtgag gagtcagatt ggaacaagcg
    29941 cacttggtcg gggtatacac ccaagaggag atgcctgagg agctggaagg cttcgtcagg
    30001 tatcaggccg tctgcgatgg ccatcaaatg aaggccgggg agaggatagc cgtgctgaac
    30061 gtcaccggca cctcctcata cgtcccggtc ttcatggccg acctcaaggg ctacgacgat
    30121 ctggaatccc ggctctcgaa gcatggggtt caggcagacc aggtgagcgc cctatccctg
    30181 cggcgggtac tgcaggagat gggtcacagt taaacccctt ccctacgttt tttattgccc
    30241 agtaaaaaga tggtgattgt tttggcaagg agaaaactta ttaatagggt tactggtttc
    30301 cgagttcatc tcacgattgg aggctattaa ttggctgcta ctaaaaaagc gtctacgaag
    30361 gccgcctcac ggaaggtcaa ggaccggtgg aaggccaagg agtggtataa gatatacgct
    30421 ccgcgcatgt tcaaccaggc ccagctgggc gaaaccccca gtgccgatgc cactaacctg
    30481 atcggcagga ccaccgaggc aaccgttcac gatataaacg gcgacttctc gaagatgcac
    30541 gttaagctca agttcaaagt tcaggacgta aacgggttcg atgcccacac cgtgttcatc
    30601 ggccaggacc tgaccagcga ttacatcagg cgactaacgc gccgcaagcg gaccaagacc
    30661 gaccatgtca tcgacgtccg caccaaggac ggatacctta tccgcgtgaa gcccatgagc
    30721 atcaccgaga agcgcatcca gtcctcccag gagaccgctc tgcgcacctt gatggacgct
    30781 gagatggcta agatgggaga ggaaaagacc atctccgaga tcatcaaggc catcatcgat
    30841 ggcgagatgg cgcacaggct gggcagcgtc tgcaaggtca tcgtccccat caagagggtc
    30901 gagatccgca agaccgaggt gctggagatg ggcgcaggcc cccaggacca gccggtcttc
    30961 gctcctgagg cacccgctga gcccgaggct gtcgctgaag ctccggccga ggaagccata
    31021 gtggctccgg ccgaggccga gcaataaacc tcttccccga atgccggggt ggctcagcct
    31081 ggtggagcgt cggactcata gggattagga acaagaccct ctccagggaa atccgaaggt
    31141 caggggttcg aaccccctcc ccggcactcc cccgccactc tcttattctc cttatcatcg
    31201 cctgacaaag caatcattca agtacgtccg ttcatcttgc atcttttcgg tgagagaacg
    31261 agggtaataa tctatactgg caagggtggc gtcggtaaaa cttccgtgtc cgccgcgacc
    31321 gccctgcgct gcgccaagat gggctatcgg accatcgcca taagcaccga ttccgctcat
    31381 tcactggccg attccctgga tatacctctt tctggcgaga tccggaagat cggaaagaac
    31441 ctggacgcca tcgaggtgga cgtgatccat gagatggaga accgttggca ggagatagga
    31501 aagtatctca gcgacttcat ggtctcccag ggcctcgatc caataacctc caaggagatg
    31561 accgtctggc cgggcatgga gctcatgtcc gccctgttct acatagagga gttccagaag
    31621 agcggggtgt acgacgtggt ggtgatggac accgcgccta cggcggagac gctgcgattg
    31681 cttagcttcc cggacaccgc cgactggtac ttcgacaaga tgtacaagat attcaggaac
    31741 actgtccgtc tggctcgggc cacggtcggc aaggtcatga gcatgcctat gcccacagac
    31801 gccttcctga acgacctaga tcacctcaag gaccgcctga agtcagtccg tcagatactg
    31861 ctagactcgg aaacgacctc cgtgcgcctg gtgctcaatc cggagaagat ggtcatcaac
    31921 gagaccaagc gtgcctacac ctacctttcc ctgtacaacc tgaccgtgga atgcatcgtg
    31981 gtcaaccggc tgctgcccga ggaggcccga cagcactatc ccgaggtcaa gtacgaggag
    32041 cagtcccggt acatgcaggt catcgaggag tccttctctc ccctgaagat gctcaaggcc
    32101 taccagtccc cgaccgaggt gatcggcaag aggtcattgg aggccttggc caaccaattg
    32161 ttcggagata cggaccccgc gcaggtgtat tccaccgaga agagcatgga gatatacaac
    32221 cgggacgggg tggaccagct atctctgaaa ttaccgttct ccagcaagga ccaggtagag
    32281 ttatataaat cgaacgatgt cttaattgtg accgtaggct ggtacaagcg ctcggtggcc
    32341 ttaccttatt cgttggtgaa gaaggaggcc cacaaggcgg agttcaagga cggccgactg
    32401 gtcatcagct tcaagtgagg tattcaaatg gcaagcaaga aggaaggtac cgaggaaaag
    32461 aagcaggaaa cgccatctcc atcgttcagc agcggaccca tgccgcagga cgccatggta
    32521 catcttttaa agtcggggac cgagttcctg gccgccatcg acaccctgat gccgcgcagc
    32581 ataatgcccc cggaggccaa ggtccattac aacaacatcc gcaaggagac gctattgatg
    32641 ttccgctcct tcatcgactc ccagctgagc gatatcgaca agaagaagga ggcgcccgcc
    32701 ccccgcctgc gcaagatcga cctcgattga actactcctc gcggcagtcc gggcacagca
    32761 gggacccgtt ctccagttcc agagcgatcg aataggcgtc acagctctcg cagtatccgg
    32821 ccagtttgcc gaagccgttg gcccgggctc ctggtatggc gcctatcttc gaccattccc
    32881 tggtcagctc tatgagcgac ggggacagtt tcaggatgtc cttctcggtg agcatcccta
    32941 tgagcttgcc gtcctccacc actggtaggc gtctcatgtg cagctcggac atgcgtttgg
    33001 cggctatgga cacgttcgat cccggggtga tggttatgac cggcgaggac atcaccttct
    33061 ccaccttggt cctcgagggg accttgccga cggcgaccac cttgtagagc aggtccctct
    33121 cggtcaatat cccgaccggc tgtccttcct ccagtatgat caggctgccc acgctctccc
    33181 ggagcatcag ggccgctgct tccttcacgg tcatgtccgg tcgtcccgtg cgagggcggc
    33241 tggacatcac ctcccggacc agtatctccc ttacctcctt ggaccgcatg tttatcatat
    33301 tctcacgggc actagatatc tctgccgtcg tgatttcacg gttcgagaga gaatcagggt
    33361 ctgaacatcc acagttttta atatcgcgta ggtcaacaat aaccggggtt aagcatgaag
    33421 gaccaggaag gaggcatggc ggtcaagttg gcccgccggg ccattgatgc ggagaccagg
    33481 gacctggacg tcgaccgttt cgacgttccg gatggcttca ggaggatgag cggagccttc
    33541 gtcacgctca agaccttccc tggggacgag ctgcgcggct gcatcggtta tccggaaccg
    33601 gtgttccccc tggccgaggc gatactcagg gcggcacagg gtgcctgcca cgatccgcgc
    33661 ttcccaacgt tgcgaccgga agagctggac caggtggtgg tggaggtgag cgttctgacg
    33721 ccaccgatgg agctaaaggt ggacgaccgc cgggaagtgc cgaaggccat cgtcatcggg
    33781 agggacgggc tgatcatgga gcgggggatg taccggggac tgctgctccc ccaggtcccg
    33841 gtggaatggg aatgggacgt caccaccttt ctggagcagt cctgcctgaa ggccggactt
    33901 cccccagaca tgtggcttga ccggaagacg aggatattca ccttccaagc ggagatcttc
    33961 cacgaggaat cgccatacgg tcaaatactc cgggaacgta cccagtgatg gcatggacgt
    34021 cgtagagggt aagctgttct accagggaag attgcagaag gcctgcgtag ggatcgagga
    34081 cgggcgtatc gtcagcgtga ggaaggtcct caggggcgac gagcatttcg atttcggtga
    34141 tcgcctggtg cttcccggag cggtagatcc tcacgttcat ttccgcgatc caggtctgac
    34201 cggtaaggag gacttctctt ccggttcgct atcggccctc tacggagggg tgacctgcgt
    34261 tctcgatatg ccgaacaccg tgccaccggt catcgatgct tcatcattga aggagaagcg
    34321 ggaggcggtg tccggccgct cctggataga ttacggtctc atggccggca tcgctccccg
    34381 gacggatgtc gcctcgctcg gcaagtgcat cgcctacaag atattcctcg gatcgtccac
    34441 ccagagcgtg ctcctgaagg aagagaagga cctggccagg gcattggatg aggtgggaag
    34501 ggccggacgt ccggtgagcg tgcacgccga ggaggacgcc atgctgttgc gaatggacga
    34561 acggtctctg cgcgatcacg aggagtgccg tccccgccag gcggagctgg cagccatcga
    34621 gaggctgaag agatatcatg aacgcgctcg tatcaatgta tgtcacgtga gctgctccga
    34681 ttcattatcg tcgctgaagg gaagcgggat gaccttcgag gtcgcgccgc accacatgct
    34741 gctggactcc agcatggacc tgggcgtgtg ggggaaggtg aatcctcctt taaggcgcag
    34801 ggccgatcgg gaggccttgt tccaagcgtt ctgtcgggga gaggttccga tgctggccac
    34861 cgaccacgct ccgcacactg ccgcggagaa ggagagaggg ttcggcgagg cgccctccgg
    34921 actacctggg gtggaaacag gtttcgccat gatgctggcg ttggtcaaga aggggttcct
    34981 atccatggac gtgctgctca atgcggcctg ctccaatccc gccacgacct tcggattgaa
    35041 caagggtcag atagcggaag gtcgagacgc cgacctggtg gtcatcgacc cccgagaggt
    35101 cacgataata aaggggagaa acatgcacag caagtgtgac tggactccct acgaagggag
    35161 agaggcgctg ttcccgcagg cggtgttcct gcgaggaacg ctagtgctca aggacggctc
    35221 gaccatggcc gagcgcaaag ggagggagat atcgtatgct taacggaccg ctgccgctgg
    35281 accttagcga gctggaagga aggaaattcg tgtgccagga cccctgcaag ctttgctgcc
    35341 tatgccagcc ggagtgcctg cctgaagagg tcgatttctt caagaagaac tatccgaacc
    35401 gcctggtgct caagaaggaa ccgcataagc attacgctct ggccctgaag aaaggtcagg
    35461 gatcgtgttc cttcctgcag ggaggaagat gcgaggtcta cccacaccgc ccgcatttct
    35521 gccggcaatt cccgttccac attcacgtcg ggtcgagggc ccagatagag ctggacctca
    35581 gctgccgcgg ggtgtggctg ggtcaggggg aggacgccat gaccgaaggg ctgcgcatgg
    35641 tgcaggaaaa ggagacggag atccgacgga ccctgaagga atccgttccc gtctaccggg
    35701 agttcaccct gaactgccag gaggccggtt tggaaattga cgtcagcaag gtgcgcgccc
    35761 aggtagccgc tcgattggac gagcttacgg acctgcgctt gatcgcctcg ctgctggagg
    35821 agagcgtgga ggaggacgag ctctccattc ccgggctgaa ggcgaaaccg ttgctggacg
    35881 ccaagaccat gggcgagctg tcgcattccg ccctggagat ggtcaccgat tccatggccg
    35941 ccgacgaact gttccaggcc ccggtgtact gcgccccgga cgggagctgg aacctgttcc
    36001 gcgttctagg tcaaaaggtg gagtggcacg tgctgggcgt cgagggtgac gtgaccaaga
    36061 ggggcgagct tccgatcaag gacatcaagc tgcagcagcc cgagggccgg gaccgccagg
    36121 tgctgcgaga ttacctcaag atactgaacg accgggacag cttcatgggc tacgccttct
    36181 atctgatgga cgactacgat tacgaggacc cctggccgaa cgtgtacggc ggagttctgt
    36241 ccacatccat attggacctg ctatggagga cctccctgat cgccgccttc ttccccggga
    36301 tgaaggacgg ggagcgcatg agggagggga taatcttcta cgacatggac cgcttggacg
    36361 cgcctacgct gggggcgttc atctgactgg ctgttacagg cgctacactg gagcacaaaa
    36421 acttcatata gtgaactctc attcgcacga taaggtgaag tgagcatgca gaaaccgctg
    36481 aatgtcctca accaggcgat aaacaaccag gtcatcgtca cgttgaaggg caaccgcgag
    36541 taccgagggg tgctggacgg atacgatccc cacatgaact tggtgctcaa gaacgcggag
    36601 gagctgatca acagcgaggt cgtccgcaag ctcacagtga ccattgtccg cggcgacaac
    36661 gtaatttaca tctcaccctg aggttattct tatgacgaaa ggtacggcat cacacggaaa
    36721 gatgggagac aagaagacgc acgtcccctg ccgcagatgc ggaaggaggg cctacaacat
    36781 acgcgcttcc ttctgcgctt cctgtggata tggcaagacc gccaccatga gaacgtataa
    36841 ctgggcaaag acccattgac gttcgaggta gctcccttgg aggatgaccg tccgaagcat
    36901 ttttgcggga tcgtcggcat ggccctggag ggcgatgtcg tcccccatct gaaaaagtca
    36961 ctccggatca tccaacaccg tggccaggag gccgcgggaa tagccgtctt caacggcaag
    37021 accatgtcct atcatagagg gatggggcta gtgcatgagg tattggtcgg acggcagtac
    37081 aatgcgctgg tgggcaacac cggcatcggc catgtccgct actccacttc cggctcgtcc
    37141 tgcgcggaga actgccagcc tataaccgtc accaccaagg aaggcgatct ggccctagct
    37201 cataacggcg atatcgtcaa cgccgcttcc atccggacca agttacaggc ggaaggctgg
    37261 gcgttcttga cgtccaccga ctccgagatc atcgttcgca taatggccac ggagctttcg
    37321 ataagtcctg atccgattcg ggcgatcaag acggtcatga agaccctgga aggcgcctac
    37381 tccatcgtaa tgatgatcgg gggccgcacc ttcggcttcc gcgatcctta cggtttccgg
    37441 cccctgtgcc tcggtaagct atcgaacggc tacgttctgg cctccgagag ctccgtgttc
    37501 gacgtcctga ggggggagtt catccgggac atccttccgg gcgagatagt ggagataacc
    37561 ccgaccgggg tcacgtccac tcgaactccc gccgcgccgc ataaggcgca ttgcatgttc
    37621 gaatgggtat atttcgcacg tccggacgcg gtgatcgacg gtcaggaggt ctatcgcgta
    37681 cgcaccagca taggacacat cctggccaag gagcagccgg tggacgctga tgtcgtcgtc
    37741 ccggttcctg actccgggcg agctcacgcc ttggggtacg cggaaggctc tggtattccg
    37801 tacgctgaag ggttcatgaa gaaccgttac atcgagagaa cgttcatctt accggaccag
    37861 gcccagaggg acgagggcgt tctcctgaag ctgaatccca taaggtccac cgtggccggg
    37921 aagaaggtgg tcatcgtgga cgattccatc gtccgcggaa cgaccatgct caagatcgtt
    37981 cagatgaccc gaagggccgg agccaaggaa gttcacgttc gaatcggttg cccgcccgtg
    38041 atcgcgccgt gcttctatgg cgtggacatg aagaccaggg agcagttcgc cgctctgaac
    38101 cgcaccccgc agcagatagc cgagcttatt accgctgact cggtcggcta catcagtcag
    38161 gccggtctcg tggaggctct gcggatcccg gagtccgagc tatgtctcgc ctgcgtgaac
    38221 ggcgagtacc cgaccaggat cgtcggcgag aagatgcgct tccagaagac ccttgaggtc
    38281 tgatccgtcc gtctcatcga tcggccggta agcattatta tcctatggaa atattgtcaa
    38341 ccatgggtaa caaggtccgt aggaatcgtc cgctcggcgt gacgataatc ggcgttctgc
    38401 tattcatttt cggcctgttc atgatcctag gtggcatcac cttgggtgcc ctgacggacc
    38461 tggaagggtt ggacctggcc atcgagatgg tcgctctggc catgggagtg atctatatcc
    38521 tggccgcctt cggattcttc aagggctggg gtttcgtctg gctgctgacc atgatagtgg
    38581 tcgtcatcgg gatcatctgg aacatactgt cctgggtcct cggcggtctg gatatggaca
    38641 aggtcgcgag cctgttgatc ggtctgataa taccgatcat aatcctgctg tacatgaaca
    38701 gcagcaacgt gaagacgttc ttccgccgtg gctgaaaacc atttccttcg ttcaattttt
    38761 ccaggaatgc caggccagac cgggatatta agataagatt aaatagagaa aatcgctttg
    38821 ccaattccac tgggcaggta gatcagctgg aagatcgcta ccttggcatg gtagaggccg
    38881 ggggttcaaa tccccccctg tccacttctc atcaatgatt tttacctcat tccattttta
    38941 tcaagatcca ttatcaggtc cgatggatgg gcgccgggaa aacgccaagg atagcagatt
    39001 tataaagtta ataaacacac atatgatagt tcaccaatga aggcgatcgt atggaccaga
    39061 tacggtcctc ctgaagtcct ggaatataga gatgtctcca agcccgttat atgtaagggc
    39121 gaggttctga tcagggtata cgccacttcc gcttttaccg gcgattgcga gctaaggcgt
    39181 ttccaggttc cttcatccct ctggcttttc accaggctgt acctgggttt gaccagacca
    39241 aaacgggtca ccattctcgg ccaggagatg tctggcatgg tggaggctgt cggccagggc
    39301 gtatctaatt tcgcggccgg ggacatggtc tttggcctga ccgggatgcg cttcggaacc
    39361 tacgccgaat atgtatgcgt tccaaatggc gctttgatgg tcgagaagac ggacggtctc
    39421 accttcgagg aagcggcggt actgtccgtc ggggggttgg aggcgctgca tttcatagag
    39481 agggcgaaaa tacgggaagg acagagggtg ctgataaacg ggggaggagg tagcataggc
    39541 accctggcct tgcagctggc gaaagatgcg ggcgccaagg tgacctgcgt ggacagccag
    39601 ataaaactgg acatgttgaa ggatctgggc gccgatcagg tactagatta tacgaaagat
    39661 gatattcttg gcaacgcgga gggatacgac gtgatcctgg acctggtggg gaaaacacct
    39721 gtcccagagc tggtgcgcgc gttgaaggat cacgggctcc tcgtcatggg caactcagga
    39781 cccttcgctc ccaagctttt cggcctctgg gcgtctatgt ctggcggaaa gagggtggtg
    39841 tccaatcaat cgtccggtac gatcgaggag ctcgagaggc ttagagacct ggtgacatca
    39901 gggaaaatcc gattggtcat cgaccggagc tttccactgg agaggaccgc cgatgcgcat
    39961 cgctacatag aacagggtct gaagaagggc aacgtcgtga tcaatgtggc cggaggaaag
    40021 ggaagctgaa gcgatctagc caggcgttaa ggttctttcg gtgagtatcc ggtcagtatc
    40081 tccctcagga tgcggccttc ggcctttctc aagtgctcca tcagcgtgcc cttgctgatc
    40141 cccaacttct tggacagttc ttcgctcgat atcttctttg ggtagtcgta atagccatgc
    40201 tgataagcgg tcatcaccgt ctccctctgt ctgtccgtca gcacgctcag gacatcctgc
    40261 ttttgatagg ctgccctcat gaaggacatg ctcgtgatcc gctccgcggt gggcttgacc
    40321 agttccagga acctccggag ctccttttgc tccgctagaa cgctgaccac cattcggtcc
    40381 tccgatatct ttgtcggggc tgtatagatc aggtcaaggt cgaactcccg gaactcgtcc
    40441 tttctctctt ccggctcatg atgtttgatc aggcagaccc gcttcctccc ttccgatcgg
    40501 aggacgctga gtatctccat atcacctatg ttcgtccgtt ccgcgatctc gatgtcatcc
    40561 ttcagtatga actcgaccag atcgatgcag gtgcattcct ccagatcgat tctcagagac
    40621 tcgaggatct cataggaatg aatcttttcg aataagggcc gcatctcctc tttcgtcgat
    40681 gggctaggaa ccatgtccaa gatgagcttt ctcatcaatg tacaataaaa ttgtatggct
    40741 atttaaagaa ccccacatgt aaggctcaat ttgcttcaat tcgaccatca ctaccttcga
    40801 acaaggaatt aggaagtgat aatgaatgta cagcgaaagg gtgtggaaaa agagaacgga
    40861 caggtccgtg tcgggtcaag cagatcagga tggaccaggg gcaaggaccg catggccaac
    40921 gaagaggctt gcgctcacgg caggccttct ctatctaggg gtgatcatct tcgggatctt
    40981 cgcccagatg gccagaatgg atctcatagt gccggaggat gccggggcga ccgtagctaa
    41041 tatcttgggt tcaagtggat cgctccagtt ggctctggtg agcgatatcg ccatgtgctc
    41101 ctgctttatt ctgttggggg tggtctccta cgtgatgttc aagaagaccc atgactgcgt
    41161 cgcgtggatc atgctgctcc tggtggttgt cagcggtgcg tacgcctttt acaacctaca
    41221 caacgttata gaggccatcc agatagtcaa tggcgccggt cagttgaccg ttgacgaaca
    41281 ggaaatggtc ttggctctgc tgaacgctca cgaggacggc acgtacatcg cgaacgtcat
    41341 tggttggggg ccgtggctgg ttcccctggg ttaccttggg taccggtcag ggttcgttcc
    41401 caaggcgata gggttcatcc ttatcgccgg gggcatcggt ctgaccgccc agagcctgca
    41461 gtatttcctg ctcccggacc tgggcgacct gttcgctccc ggggtcgttc tatcgatcat
    41521 cggggagttc gcaatctgcg cctggttcat ctattccggg gttagaggga acaggttctc
    41581 ttcgggaatt gatgagcgca cgaaagagat cgatccagtc gatcctcgat aaacctctct
    41641 tcaaaaagga caggagtgat cctcctgtcc ccactttttc ttttcatatt cttgggcaac
    41701 attggttcaa aagggttcaa attcccgctc gcatggatct cggacggtac aatgacccat
    41761 ggacagaatc atcgatgatc accagggtga tctattgaca accttcggcg cccttcaatc
    41821 cttctcaatc tgatccgcca tatgttcttt cccccaacag tagagctgct cgaccattgg
    41881 ttgaagtgaa tgacatcgtc agcaggagaa caggttcgtg ctcaggtact tctccccacg
    41941 gtccgcgaac aaggtgacta tggtcccgga atcgatgcgt ttggcgatct cggccgcggc
    42001 gtacatggcc gccccgctgc tcattcccac gaagatgcct tcctgtttga ctatctggcg
    42061 ggtcatctcg taggcgtcct cggtctccac catgatggtg atgtcgatct tgctcggatc
    42121 gtatatcgcc gggacgatgg cctcctccat gttcttcagg ccctggatgt aatgcccttt
    42181 gaccggatga gcgctgacga tcttgacgtt gggattgtgc tccttgagcg ccctgcccac
    42241 gcccatgatg gttccggacg ttcctaaagc ggaaacgagg tagtccacct tcccgccggt
    42301 ctgtttccag atctcgtcgc cggtggtctt gtaatgcgct atcttgttgt acttgttgga
    42361 gaactggtcg ggcatgaagt acttgtcagg gttctcggcc accagcttct tcgccaagcg
    42421 gatcgccccg tccgtgccgt ccgtggctgg actcaacgtt acggttccgc cgaaggcctt
    42481 gatcatctgc ctgcgctcga cggaaaccgc cgcgcacatg acgatctcca cgccgtaacc
    42541 cttaatcgca ccgatcatgg ccaaggccac accggtgttc cccgaggtcg gttcaattat
    42601 ggtctttccc ttggtcagct tgccttcctg ctcggcctgc tcgaccatgg ccaaggctat
    42661 gcggtccttg atgctgccag tggggttgaa gccctctatc ttggccaaaa tggtgacgtt
    42721 gggattggga ttcagcttat tgatcctaac caaaggggtg tttccgatcg actggagtat
    42781 gtgttccttg taatcggggg ttggagtttt catggtcagc tctccagata ggaaaggtga
    42841 gattaataat tactatatct cagctaggga gctaatcgaa taagacggca gcgctttttc
    42901 cccatgtcaa catcgatcag atatcaatta ggacgtcccc gccctcgatc gagatcttgt
    42961 agatgcccag gggtttagcc ttcccgatca gtggtatcct gacctgagaa actacttcgc
    43021 cagttcgcac gtcgtatctt gaaccatgtt tagggcattt tacgacatgt ccatcaagcg
    43081 aaccctccca aagccgagcg gccatatggg agcagagtcc atccatgcca taaattaccc
    43141 catccacatt ggctagcaag atatgtctgc catctatttc cacgcctttc atggtccctg
    43201 gcggcatctc tgagagcaaa gcaaccttct tggtcggcat gatctaagat aatgcaggga
    43261 ttgaggatat attatcgccg cgaacggtct ttcctctatc caaggtcctg aaagacccgg
    43321 tctcgtgtcc caatacgcct aatgaccttt tccaatcgaa aaaggaacca tatggtcgct
    43381 cgccgtcacg aattagacac atcatcattc atcgcgactg aggcaagggc catataatca
    43441 cgatctcctt ctatgggcgg gacccagatg ataatcgaca gccacgttca cctctggtta
    43501 cgggaccatc tcccggacgc catggtccgc atgtaccttg aaccactcat cgccctggaa
    43561 gggctcatgg actgggacgt gcaaacggaa acggtctggc ccgagtacac cgtgggccca
    43621 gataagatcc tggaggcgat ggacgacggc ggcgtggaca aggcggtcat tctgcccatc
    43681 gacttcaatc tggtcgagaa ggccaggctt gatgtgaacg agtacaatac ctgggtgttc
    43741 gaaacctgcg ccaccgccgc cgaccgtctg ataccgttca tcggcgtaga cccccagaga
    43801 ggcgaccagg cgctcgatgt tctggaccgt tacgtgaaaa gatacgatgc caggggggtt
    43861 aagctctacc cgtccaccgg ctggtatccc aacgaagagc gtgtgcgcag gttcctggac
    43921 cgcgtggacg aactgggtct ggtgatcgtc acccacgccg gggcggcctg gggctcactt
    43981 gatgaaaggt tcagcgaacc atccttctgg aacgaggtcc tgcaccgcca ccccgatacg
    44041 aacatcgtgc tggcccacct aggcggaagg tggagacagc aggcctacca gatgtgcaag
    44101 gaatatccca attgcttcac tgattgctcc gctctgcaag gctggcttcc ttccgatccg
    44161 gagaccgcca tctcacggtt gaaggaactg gccgcgacca tcccggacaa ggtgtccttc
    44221 ggttccgatt tcccgctgtt cgagctgagc tacaccactc cgatgtgggc gcacttcgtc
    44281 aggacccagc cttgggcgga cgaagatacc agggccaaac ttctaggcgg gaacatgcga
    44341 aaggtcctgg gcatctgagc ggcaaaatct aatctagtct ggagtcgatt cacccaagcg
    44401 atgatcatcg acggtcacgt ccacatgtgg ctccggccta tgtatccgga tgtcatcata
    44461 aacgcctatc tggaaccctg gctggccatg tcggagttcc tggacatgac cgaggagatc
    44521 gagaagagct ttcccacttc cgaggtgcgc ccggaccttc tagtggagtt catgaagcag
    44581 ggcggcgtcg accggtcggt cgtactgccg ttggacttcg gcctggttca ggaacctaag
    44641 gtcggcgtcg aggagttcaa cgactggata tttgagtccg cggcgatcta cccggacaag
    44701 ctcatcccgt tcatgggcat cgatcctggc cgaggcgagc aggccatacg cctgatgcgc
    44761 aagtacttcg ccaagttcga gcccaagggc atcaagatct atcctccgaa cggtttctat
    44821 ccgtatgaag agaggctaaa gccgttctgg aaggaggtca gcgacatggg tctggtcgta
    44881 gtgagccacg ccggcgccag ctggggtccc ctggacgagg agaagagccg tcccatacac
    44941 ttccgcagcg ttcttgacaa gtacccggac ctcagactca tcatcgccca cctgggcggc
    45001 aaataccggg cggacactta cgaactggcg aaggagtacg ataacctata caccgactgt
    45061 tccgctctgc aaggctggct tccggccgag ccgcagatgg tcaaggaccg cctgaccgaa
    45121 gcgttctcgg taatgggcga ccgggtgatc ttcgggacgg attggccact attcgacctc
    45181 tcctatccct acgaatcgtg gtgctcctta gtaagagagc tggacatctg ctccgagggg
    45241 cgtagggaga aactgctcgg gggaacgatg cagaagctgc tggggatctg atcaggccca
    45301 ggggttcccc cagctgccat caaagaagtt ctctccgacc ggcttgcgcg gcggtctttc
    45361 cacctcggcc aagagctgct tctccgagag catggaaacg tccgaacccg gatagccgca
    45421 tatgatcaat gttatcagaa cctggtccgc cggtatccca agcttttcct ttatggctac
    45481 ggggtcatat ccagctatgg gatgggcgat cagtcccatc tcggtggccc gcaacatcat
    45541 ctcgcccacg gcaagtccgg tgctgaaaag atgataatca cgccggtcgg tgagcttgca
    45601 atcatcgtcc aggcgggagc atacgacgaa tatcaacggt gctttcgtag cccatccgtt
    45661 tcctcggggc agggaggagc ggatagcttc cagggacgat gggtccctgg ccactatgat
    45721 ccgccatggt tggttgttgt tgcaggacgg tgaaagccgc atggcgtcta cgagctcaga
    45781 gatcaatcca tccgacactg gcttggcgtc gaacgccctg gtggcccggc gcttgtcaac
    45841 agcttccttc acgtccatgt tatccgaatg tgaacgctcg gtcagttaat atcgtttgcc
    45901 ggcgcggcac ttggttcatc cttgatctcc cgtagatgtg cgccgcgtat ggattctgct
    45961 ccatcctacc ataaaccttt aaatcggaaa cggtaattgc ggagcgttcg ggcccgtggc
    46021 ttagctggat atagcactgg ccttctattc cccggcaacg ggggagaggc aagtcagtgg
    46081 tcccgggttc gaatcccggc gggcccgcca atgaatattc taaagaaaaa taaaaaaggt
    46141 gggcggaggg ctctcagagc tcctccaacg cctccttgcg ttccttctca tactcttcct
    46201 ggctgatgat tcccctcttg cgcaggtcct cgatcttgtc cagcttctcc gcggcgctca
    46261 tcttcgaagg ctggttgacg atggagaccg gcgtaacgtc catgtgtatg accgcgctgg
    46321 cgatcttggt gacctcgaac ggcttaccta cgttctccca ggagaccgct ccgccgctca
    46381 tcagcttgat gcccggcgat tcgtaatcga taccgccctt ctccccggcg gtggcgaaga
    46441 acacgtcccc atatcccaat atcctctcgt accagggttg gatggtggtg acgctctgca
    46501 ccttctctat tccggtgtca gcgtatcgca gggtgaagat accataacgg gtgattatcc
    46561 tctggtcggt gaccacaaag agcacccggc tgagatagat gtagttgatg gccaggagca
    46621 gcaaggcgaa gaccagcggt atcaggtacc aataccaggg caattgcttg tcgatcaagg
    46681 cggtccaggt gattatggcg atcccggcca gtcctccgat caagccgagc ctcttacgat
    46741 cggtgatgat catcaacaaa caggccgcga ccgcgatcac cagcaccaga aggtcttcgt
    46801 tgctgttgta taagaactcc atcagcacta agtataccaa ggcgaaggcg gtcagcaaca
    46861 atcctttgcc catgatgatg atggcggccg gtttcccctg ccacttgatg ttctcccctg
    46921 atatcaggta gtccgaggcc ggcgaaccgc tcgccgcccg ggataacaat gaacccccct
    46981 tgttcttccc catttttctc ccctcctcct gcaccatggc aatacaagtc ctttcggcca
    47041 catcgtccta ggatgcggaa gaaacatggt cgtgttgaat attataatga tttgtgatac
    47101 ggtgccagtc ttcgacaggg tggcggtcat gccctttctt ggtcgagtgg cttttaatat
    47161 actctcattg gtgcgagaaa aggaaaatca tgggccatat gagagctcgg agggacgtcg
    47221 gggagcaaaa ggttattaaa gaacgattgg atgagggcag ctagtctggt gtgtactgat
    47281 gaagagaagt tcacgcgcct ggaagaagaa aggcaagcag cgctggaaat ggcgcaagaa
    47341 aaagatgaga cggcgaaagc acgcccagaa gatgcgtaag cgttaaagct gaaccagtgg
    47401 gggtatgggg taacacggta tcctcgcggg ctccagttaa tatggagtga ttgctaacgg
    47461 gtttgctgat ccggtgatga ctaactggag cgatgacctg ttaattcgcg tggggtcgct
    47521 ccccacgtgg tggaaacccg ctgatctggg ttcaaatccc agtgccccca cctcattaac
    47581 tttccaaaca ggccagcacc gttaaaggtg cggcccccct ttgctttttt attttttatc
    47641 atttcttatc tacgccatgc atgactgagt cgacgaggcc tcttttcaca gattaatcag
    47701 tttggtcgat aggttaggct tcgtggggcg gatgtttata tgaatggctc tcatacaaag
    47761 attgaggctg ctattgaaca tcaccatctt cgccttcatc tacgtcatct gcgctgccgc
    47821 ggctctgttc atcagggtca tcttcatgct gatgatcggt gaccgtaagg cttacaggag
    47881 ctcctttacg gacaaactgc tggtcttcct gatagtcgcc agtatgatcg cccctctggc
    47941 atacattctc actcctcacc tcaacttcgc taactatcac gtaccggacg ccatggcctg
    48001 gtcaggtgcc gtactgatcg tggcatcact tcttctatta tggaggtcgc acgccgacct
    48061 gggcgttaac ttcgcgctaa cccccggagt tcatggggag caatcgttgg tgaggaaagg
    48121 ggtataccgc cgggtgcggc atccgatgta cacctcgtta tggttatggg ccttctccat
    48181 gccgctgttg ctacataacc tggtcgccgg ggccatattc attgcggtgt tcggttcctt
    48241 ctacttcgcc cgcgttccga tcgaggagaa ccacatgacc gagaggttcg gtgataagta
    48301 taaggagtac atgggggaaa ctggtagact gttcccccgc ttcaagtgaa agtctctggt
    48361 ccttgaccga tccagttatt gaggatcaag aatccgacag aacggtgaac actaatcggg
    48421 gcagcttcga tcgtggcgtt cattgaattc tcccggtgaa ccgacgtcat ttccgcgacc
    48481 acgactactt atgcgttact gtgtccaatg ggtgaaaatg ggtctcatgg ggcgttcaaa
    48541 gatggtgaat aatcaccagt cctcaccttt cttttcaaga aatgatacaa ctaaagcgta
    48601 atctttatat tcagcaagca atcctgaaat tgggagcacc ccgcggacct tctccaactt
    48661 ccccaccaac tacgttttgc ggggggtctc cttcaacttc tccatcattt gatctccttc
    48721 caggggaacc tgctcttgat ggccgaaatt accctctggt ccctggccag tcggtcactt
    48781 agcaccgagc cgtccggaac ggtgacccgg accttctcgt tccggtaatc gtcaacggtc
    48841 ttgcccatcc actccccttt gattcgtatc ccggtgccct tcaagctcaa ggaggtgtgc
    48901 agtatgctca ggtcgtacag cagttcgatc atcaaccacg gatcgtagga gatggtcaac
    48961 ggcacctcgt atgggtagct tatcagcatc gagggcacct tgtgagcgtt ggcatgggcc
    49021 ctcgtcttat cgtcattggt caggaagagc acgtccaccc gttgttcgag catctctgcg
    49081 gccacggaac ggagcatctc atcgtcccta gcctccttat catcaacaaa ggagccgccc
    49141 tgtgccgacc agcagttgta gtgttgcttg agcgccacca cctccgcctg tccgttcagt
    49201 gccttacgcc cgttcttgtt caggcagttg aacaggtcgt ctgccacaat gcggtcccgc
    49261 accgcccttc tcagctcatc cacgtctctc cgatcgtact tcttgccgac ccgcctggac
    49321 agctcctcct cggccatgga ggggatcaat acctgtactc tctggggatc gaaggagcgg
    49381 acgttgcagc cctttcccgc cagaagcaaa cgggagaaaa gtctgcgata aaggagattg
    49441 gtatccagtc cgatgcacgt ctgccgcggg aagcggtaag ggtcgccccg cctctcgtta
    49501 aaacggtata tctcggccat cagagcgtcc aggttcgtag ggggcatgaa caaggaggcc
    49561 tgtaacgcct ctcgcaggtc caggaacgtc gggatgtccc tggccatctg atcccccagg
    49621 gcgcttctca ttcgaccata tgcctcgtcg taatcccttt cccggaccac ccattgcacc
    49681 tgctggtggt ccaggtccaa ggctaggagg tctaggtcga gaaggtccga gcgcacgatc
    49741 aggttgccct tatcggccat cctggattcg ttgagaacga cggtgatgaa ctccttatcc
    49801 acctccatca gcgcacctcc ttcaagagat catgcgagct ctgcagttcc aacgggatct
    49861 ccagatacgg tcgcgaagcg ttctgtagcg attcgatgta caggtagaag atatggttga
    49921 ccttgacctt gcccgcgccg attatcgtgc ccagcacggt ggccttggtg cccggcgtaa
    49981 cgtcgacagc cactatgttg cccttaccct tctccgcggc gacgatatcg ttgaccgtct
    50041 gtccgatctg tttgatgtca tcccccggaa cgtccaccag ctccacatcc gccggggagc
    50101 cgtgctcttt gagcaagact atcagcatgt ccctggccat ctggccttgg gctgcttcac
    50161 agcctgcggt caacacgtac accttgtccg gaaggtaatc gaactggcgg atgttggacc
    50221 agacggagtt gaacaatccc cagaagctcc gtcccatcat ggtcagcagg accttgccca
    50281 tgccctagcc atggtgatgg ggaattaatc atcctttccc taaagaataa aaaaaacatc
    50341 cggaacggcc ataaaaaggt gataaaaaaa gaatgaaagg ggtttatgct tcgcagaccg
    50401 gcatctcgag gaattccggc agccagagct tgaagtgcat ctgcccgttc acatagtgca
    50461 gcaggagatg ggccttcagg tccaagttga agtccagcgg cagcgaggat atctccccgt
    50521 tgacatgggc gttgatgatg gccgatccga tgcctccgtc gtagatgatg acgtgggcca
    50581 ttatctgaag gttcttgatc tccagggcca gcacctgctc tccgtcaatg aatatggtga
    50641 tgtccccgtg ccagaacgcc tgtagcttca catccaggct gtccttcttc tcccaggtct
    50701 tcaggtttac atggaccatt ccgtccaagg ccacggttat gacctcatcg tcccactcct
    50761 ctaccaatct cagcaggcag gggtgctctt ccgcgatcct ctccaggtcc tccggcggga
    50821 tcatttccag gagcgcgtcc aggtctcccc gctcaatatc aaaggccacg tcgatcttct
    50881 cggtgatcac gacatccgcg accttgccgg cagcggaggt cgtaggggcg ctcaaacaaa
    50941 aggcgcccag catcgcaaat gccatcacga tagctagaac tgtccttagc atgtgtttca
    51001 ttaggtcccc cctagggact cgggtccccg gtgatattca cttgagattg gcgctttaaa
    51061 taatctgcgg cccggtcaac ccagtatgcg gcgtatggcc gcctgggttt cctgcggggt
    51121 ggcggtggtg ttcaccagat ggaccctcga ttgggacagg aacttgcgga agaacgtctc
    51181 ccggagcttc atcttccgct cgtctcgcac catctggtgg gggttgcaaa ggtcgttcgc
    51241 cgataggtac tcccaggcct cctctgatgt tagctccctc accagtcgag catcgctctt
    51301 gtcgcgcttg agcatgacca cttcgtgaat ggtggtcaag gggacgactg aacctttacc
    51361 ggtgacccat cgaacgttca cgaccgccct ctggcggttg tcgaacttgg ccttcttcac
    51421 cagttctcgg tactcgtccc atatgctccc gatgtccgcg tcgatgtagc agttcttctc
    51481 agagccgtag gccaccggtc gcctctccga cagacggacg aagtaccagt catcggtgac
    51541 cagccgggcg ttcttgtctc tcagtaggcc ccaggagtgg gtggtcttgc cggtcttcga
    51601 cggggcgatg agcgttatcc cctttccgtt tatgtccagg gcggcgccgt gcaccgaatg
    51661 gatctggtgc tcgtcctcca gtatgtcacc ggccagagcc aacgccacgc tcttgatcca
    51721 cccgtaatag tcgaagttga acaggaaggc cgtcttggtg ttgggttcaa agagcacttc
    51781 caggggtcgt cccggatcgt ccaggcagat cacccggcca tgggagcgaa ccgtttcgga
    51841 catggagtag aagttgtcct cccacatgtc cttgatatgg tcgttcagcg tgtacagttt
    51901 gacacaacag ccgctgatgt ccgctttggc ggtgtggaac gggaacgagg aatacttctc
    51961 gtacagggcg tccttctcct catacgatat caatttcacc gggtagctca tgggcagtgg
    52021 aaggcgttac tggcaattca agctaacgcc gttcccgttc acgccggccc tcatcagctt
    52081 gtattcgatg ctgtctatga gcgccatgag cgaggcttcg atgatgttgc ccgaaacacc
    52141 gatggtggtc caggtctggt taccatcggt cgaggttatg aggacgcgca ccttggccgc
    52201 cgtagcgtcc tttccatcta tgacccttac cttgtaatcg atcagtcgaa cttccttgag
    52261 caccgggtag aagcgctcca acgccttgcg caaagcccgg tccagagcgt tcactggccc
    52321 gtttccatcg gcggcggtat gctccatcgt accgtcggaa tccaccactc gtaccgaggc
    52381 ctcggacgtc atcacgtccc cggtgacgtc catgaaggta cggaaaccat ccaatcggaa
    52441 cggggaggtg ttctctccct tcagcttgcg tatcagcagt tccaggctgg cctcggccgc
    52501 ctcataatgg aagccttccg cctcccggcg cttcatcagc tccaggatcg atcgtccgcc
    52561 atccttctcg gtgtctatgc ccatctcccc ggccttggcc atgatgttgg atacgccgga
    52621 aagttcggaa acgagtatgc gacgcagatt gccgaccagt tccggctcca catgctcgta
    52681 cgtgcgggag tccttcagca ccgcgctgac atgtattccg cccttatgag cgaaggcgct
    52741 cttacccacg tagggagctc taggatcggg agatacgtta gccatctcgg ccacgaagtt
    52801 agagagcttg gaaagctggt ctaggttctt taccccggtc tcgactttca tcttgagcat
    52861 gaggttgggg atgaccgagc acaggttggc gttgccgcag cgttctccca gtccgttgat
    52921 ggtcccctgc accatggacg ccccggcctc cacggccgcc agtgagtttc cgaccgccag
    52981 ttcgccgtcg ttatgggcat gaacgccgat cggcaccttc atctcttggc gcacctgaga
    53041 gacgaccttc ccgaccaggc tgggaaaagc tcctccgttg gtatcgcaca ggcagatcca
    53101 ttccgccccg gcgtcctccg cctcatggag caccttcatg gcgtaatcgg gattgtcacg
    53161 gtaaccgtca aagaagtgtt cggcatcgaa tatcacgtgc cgccctttct tcctgagaaa
    53221 tgcgacggta tcatgcacga tgcgtagatt gtcgtccaag gacacctgta aggctttctc
    53281 cacgtgcagg tcccaggact tgccgaacac gctgacccat tcggtcttgg tttcgaccaa
    53341 ggcttccatg cccttgtcct cttccggacg tactccagga cgatgcgtgg cgccgaaagc
    53401 caccagctta ccgttcttca gcttgacctt ctgggccgct ttaaagaacg ccttgtcctt
    53461 gggattggag gccggataac cgccttcgat gaaatcaatg ccgaaggcgt ccagacgttc
    53521 caggatcttc agcttgtcct cggtggagaa agagactccc tcggtctgcg cgccatccct
    53581 caaagtggtg tcaaatatgc tagccctggc gggcaataaa taaatcccac ccgttgtttg
    53641 attttgacat tgagatacct caggtaaggt atgctttatc atggcacgac ctatttaacc
    53701 ttgccgttag aaaggcaggt gttcctcttc agcaggctga ccagatcgct cattatcgcg
    53761 ctggccgtct cctttcttcc cgcgccccgt ccggtgacgg ttatcgcccc cgccaggtcg
    53821 gtgtgcatgt gcagcacgtt gagcgtgccg gatatggaga gcggatgtcc catcgggacc
    53881 atgcgcggtg atacttcgac cccaccgcca ttgacctctc ctatgagcct gatgaccttt
    53941 ttctccttgg tcgccagctc cacagcttcc tgggtgatgc ggcggatgcc ggtacgccga
    54001 acatcgtgat aggtaacgtc caggcccatg atggcgttgg ccaggatagc caacttgctg
    54061 gcgctgtcga tgccgtcgat atcgtagctg gggtccgtct ccgcgtaacc catctcctgc
    54121 gcttccttga gcacatactc gaacggcagg ccctcctcgc ccatgcggga gagtatgaag
    54181 ttgcacgttc cgttcagaat gcccttcatg gactccacct tctcggccat gagcagctcc
    54241 ctggacagat tgatgatcgg ggtggcgccg ccgacggtgg cttcgaaacg gagctccaca
    54301 ccgttcttct tggacaggtc gtcaagcgtc ctgtacttca aggcgagggg tcctttattg
    54361 gaagtgacca cgtcatggcc gcactccaga gcggtacgga tgttggtgta ccctggctca
    54421 gcgttctcga tgttggtagg ggtcatctcc accaggacat cgtaatccag ctcgcgcagc
    54481 atctcggcca cgctctttgg tctggtcttc cccaatcctt ttccggattg tttcttggac
    54541 accagttcca ggggcttcag ccccttgggg tccatggcgt aggtcatgga gtcgaaggcg
    54601 gccactatct tcaggtccgt tccgaaccgg tcgaacacga agtccttctt catggccacc
    54661 gcctcggcga ctccctggcc aacggtgccg aatcctacca gcgcaaggcg catgtcacac
    54721 ccccatcccg cggaccagga ggaaatcgtt ccgtttgctt ctggtcatga gataatcgtc
    54781 gatatccttg atcttctcct tgttccggag gctgaccagg agcagcactg atttattggc
    54841 ggtgctggtc gaaagtgaat attgaaggtc gatggtctcc actccttcca tcttctctat
    54901 gccctcggtg atggcccgca gggtggaatg ggcgagattt ccgaccatga ggtactcggc
    54961 cgggtaggtg cgtacgatct cacccatctt gacgacctcc acgcccctct ccttccaggc
    55021 ggagaatatg gcttccaggg acctctggtc cttgtgctcg aaagtgacgt tgacggatat
    55081 gcgtcctccg gtgaccaggt catggttgtg caccaccccc actatgttcc cttcgttgat
    55141 cgatatcggc tccagggctt tgattaactg ccccggcaca tccttcaagc gcagatccac
    55201 gttgaccctc atctggtcat cacctcaata tgtgggcaaa ttgccaatcg gcggtgcccg
    55261 gccacatata tgggttcgat tatgtaatgc tttcaatcca cagtgtccga ggctggaaat
    55321 atgaacgaag aatggcgccg agggggagat ttgaactccc gaggcgttgc cgccacgagc
    55381 tagctggcgg aaattttcca ggctcgcgcc ttaccggtct gggccacctc ggcactcctg
    55441 cggcgataac cgtgggctca tttaaaacta tttgccatgt ccattatcgc agaccgccca
    55501 gcgagtccct gatggtcgga cgggccctcc tggccggctc ggtctggagc atgtccacat
    55561 cgacgacatc caccgattcc cgcaggtaag ggagcttagc caagagccgt ccacgggcgt
    55621 cgtaggcctg gcttcccccg aagtaaacca tgttctgctg gttccccacg ttgttcacgt
    55681 aggcgatcgg acaggtgttc tccacggctc gggcagggat gatcttctcg aagggcatcc
    55741 tggaagttac cggtgaggcg gcgatgcaga gcagaaggtc cgctccttgc atggcgtagg
    55801 ccttgcatat ctccgggaag aagaggtcgt agcatatgca caccccaacg cctcggccgc
    55861 ggaaactgaa catggccggc gattgtccag gtgtgaagta tagcccctct tcgaacggtc
    55921 cgaagttggc cgggtgaagt ttatcgtaac gctgcacgcg tccgtccgac gtcaccataa
    55981 cggcgctatt ggtgatcagt ccgtgaacgc atggatcgtt caaaggcatc ccgaacacca
    56041 ccgccttgcc ggtgcggtcc gccagatcca gcacgaagtt cacggaatct ccgtcaatgt
    56101 cctcagccag ggtgatgaag cggtcccgga ccatgtatcc agtgacatag gtctccggaa
    56161 agacgaacag gtcggcgtcc gtcccctcca cggtctcgac cattctctga aggttcctct
    56221 ccttgtcgcc gaccgcgctc ctgagctggc aaagggccaa tcgcatgagg tgtagcattg
    56281 aggcgaacgg tattcaacct ttgccagaaa gacaattatt aaacgggagg gcattatcct
    56341 attcgatgcc gcagctgaag gagctcaccg tggagacgat acaggagttc atccagaccc
    56401 agtttaaaga gtccggcgct tctggcgtgg tggtgggcct ttccggcggc atcgattcgg
    56461 ccgtggtgac caagctctgc gtggacgcca tcggggcgga caaggtgctt aacgtctttc
    56521 tgccctcgcc aagcacgccc aagcaggacc ttcaggacgt tcaggatatg agcaaggcct
    56581 ggggcacgac gttgctggtc tacgatatag ggcagctgct gaaggcgtat cacaagatca
    56641 tgcctgggtc ggacggcaag gaggtctccg ggaacctcat ggcccgcata cgcatgacga
    56701 tactgtacgc gcacgccaat ctggattggc gattggtcat gggcaccggg aacaagtccg
    56761 agctgctcat gggctacttc accaagtacg gcgatggcgg agccgacctt ttaccgatag
    56821 gtgacctata taagacggaa gttcgggagc tggctcgggc catcggaatc ccggagagga
    56881 taatcgataa ggagccttcc gccggactgt gggaaggtca gaccgacgaa tcggagatgg
    56941 gcatcgccta cgacgatcta gacctggtgc tttccggtct ggaggaccag cagtccttgg
    57001 acttcatctc caggaagacc ggggtgccca tggccctggt ggagatggtg gcctcaaaga
    57061 acgccatgtc aaggcacaag aggcgtctgg cgctcatacc aaagctaggc aaccggacca
    57121 tcggttgcga ctggcgtgag tgatcacagc gatctggtga cctcggccac gaagcggtcc
    57181 gggtcagata cgtcgaatat caccacgtcc accctcttcc agaaggccgc tgggactcgt
    57241 acgacacttt tcatctccag tcgaattcca ttgaccttgc tgtcggtcat gaccagggta
    57301 cggttgaagg catcgagcag aacgccttcc ttgacctcta tgcgttccaa tcgctgcaac
    57361 cgcttgacct ggtccaaagg tattaccacc ttggagtgcc agccctgccg gagaacgatc
    57421 ttaccatcga tgacctcgtg catggtcagc agaggcgaca ctccgatcac caggacagtt
    57481 atcaccaaca gggcgcccat caccacgacg aacaacaacc gttcgtgggg aaggaacgct
    57541 aggatgatca tcagccacat cgccatgatg gcccacagga ccagattgac gaatgccggc
    57601 cgccggtcgt gctcgaactg catgatgaaa aagataggtg gcagggggat tattattgct
    57661 tccttttccc agccatccgc aaggtttaat tatggccatt taattgggga cgatacacgc
    57721 tcccgtagtg tagtccggcc aatcatgaag ccctctcgag gcttcgactc gggttcaaat
    57781 cccgacggga gcaccagtct cttctactag ggtctcaacg aactcggtca ttatttgttc
    57841 tagtggtctg gaagcaaggg tcatcgccca ccaattacac atacacaagg aaggtccggc
    57901 taatcggcgt tcaatcatcg gcgggccttt ccttgatcaa caacaaggta cccgcggcca
    57961 taagcagacc ggcgatcacc agcttcgcgg tgacggactc tcccagcagt ggtatggccg
    58021 ccatggccgc ggcgtacggg ccgaccgaaa agagagtgcc ggtcctgctg gcgccaagat
    58081 gcctcaggcc gaaaaagaac agcacattgc tgaacccgta gctgatggcg ccaatgatca
    58141 tcgcgaagac catggccacc accaggtcct gtccgccgta taagatgaaa gccagcgtca
    58201 gcgagaaggt ggccgcgatg ccgctcctga tggtggagag cttgactgga tcaagatggg
    58261 agatcttctg catcaggttg ttatcgatgc cccagcaaag catggaaagt acgatcagga
    58321 tcgccccgct ccccccgaac cctccccccg gggtgtagga gagaacggtg cttgctatgg
    58381 tcatggccgc cagggcgagc cacagccggt atcccccttt gtcatggaag aacgccacgg
    58441 cgatcaccgc ggtcatcact ccctccaggt tgaggaggag ggatgcgtcg gatccggctg
    58501 tccatttcaa cccgaccatg agcaggatgg gggcgattat cgccccgaaa agggtgcttc
    58561 ccatcaagtt aaggacgtct gaacgcgcca acttggatgg cttcggccta agggaggttc
    58621 tacgcctcag cacgaacaat gtccccgtga aaacggtagc cccggcatag aggagaccgg
    58681 ccatcatcac tggctctata tccccgatca ggaccttgga gaaaggaacg cagaggccga
    58741 acagcgtgcc cgccacaagc acgagcagca ccggaccttt gtccatgccg gggaaataat
    58801 gcatatgtta attggttttt gcgtccttca atagatattc aggtcatggc gccaaggtcc
    58861 catcactcaa ggcatgtgag acagcgatca tactggttag ggaggaaccc gacgaattat
    58921 cgttgctgac ctaatcgtta acgaactcga tgctgagcgg tattcccttc ttcgtattgg
    58981 aacgagcgat catccccgcc tccacccagg ccgccgtgag aaccgccgac ggcgtcaggc
    59041 agttggcgct catgtccgag ataacgaact cccggaacac cttgctctct gtcttgtcgg
    59101 taaggtcggt catcgataac gggttcaggc cattcacgaa cctctcgacc ttggggcagg
    59161 tgctggtcac cttgacctca aaatccccgt catccgtcat gctaacctcg atgttcgacc
    59221 tgttgtcgca agggaacatg tgataccgca ccttcgatgt catttaatca ctctcgaata
    59281 tttgcaaagg acaacggctt tgagtcctta ttaaccattt ctaataaaat agaacatgaa
    59341 tatttatcgg tcctcatatc cttgaaacat catcgaatcg atgttgtcca ttctcctaga
    59401 tcggtcctgg tccttgggca tcggacggcc cttagcgttc catttttgtc gttttaggtt
    59461 ctatcgcatt ttaggtcagc aatgtcgacg aagatccacg atcttacaga tctgcccaca
    59521 tgaacttttt aaattgaatt atattaaaaa tatataaaaa ataataatta agttagaata
    59581 ataacaacaa catataaata ctatcaggcc caaaggtgta ttatactttt acggtcgcct
    59641 agaattcgat cgttgtctgg ttttttctgg atatattcaa cagaggttac agtatgaaca
    59701 ttgttttaca taaaaaaggc gagagcctca gtagcagaaa tgctacgaac aagacctatt
    59761 ttggaaaagg ttttgtcatc gcggccgcag cgctgatcgc tgttctgatg gttttgaccg
    59821 cggtccctgc cgcaggtctc gggaatgggg cgaacggatc gataaacaat tctttggcga
    59881 tggccaacgc cgaatcccaa gcatcggtcg atctagggtc ggcgggtaat ttcgtagcgc
    59941 tcgcaaaatc tggaatatcc accactggtt ccacgaacat agtcggagat atcggtgtta
    60001 gtcccatcga cagcaccgcg attaccggat tcggacttat aatggattcc tccaatgagt
    60061 tcgcgacatc atccctcata actggaaagg tgtacgcgtc agactacgct caaccgaccc
    60121 catccattat gaccaccgcc atcggtgata tggaaaccgc ctacaccaat gccgctgggc
    60181 gtacatcgcc ggatcatacc gagctaggcg ccggggatat cggcggaatg acgctcgctc
    60241 cgggactgta caagtggagc agcaacctgt tgatcccagc tgatgttacg ttagagggct
    60301 gttcgagcgc ggtatggata ttccagatcg cccaggacct cctgatcagc gagggaaagc
    60361 aggtcatgtt gagcggtggc gcccaggcag ataatgtctt ctggcaggtc ggtggacaaa
    60421 cgaccctcag caccacttcg gttctctacg gcaacgttct ctgtcataca gctatcgttc
    60481 tgaacactgg cgcaacgttg aacggaaggg ccctggcgca gaccgccatc agccttgacg
    60541 caaacgccgt caccgttcct gaatccgcca gtgagccccg ggtgatatcg accattccgg
    60601 cgaacgccgc caccggtttc tcgatcaact cgaggatatc agccaccttc aacatggcca
    60661 tggacgcatc cacgatcacc acttcgacgt tcttagtgat gcaaggggca acgtccgtta
    60721 ccggcaacgt tacctataac ggcgtgaccg cggtatttga gccaatcagc gatctggcga
    60781 tcagcactgt gtacaatgtc accataacca ccagtgtcga ggacagttct ggaaatgctc
    60841 tgatcagcaa tcacacctgg tccttcacca ctggtacgac cgcggatgtt accgcaccta
    60901 ccgtgacctt gacggtcccg atcaatgtgg cgacggaagt ggcggtggat ggaacggtca
    60961 ccgcgacgtt cagcgaaggg gtcgatcctt ccaccgtctc caccaccacg ttcactgtga
    61021 agaagggaac gatggcggtc gaaggcaccg tgacctactc tggtttgaag gctatcttca
    61081 cccctagcga ggacatcgag tacagcacca actacacggc caccatcagc accggggtcg
    61141 aggacctggc aggcaatgcc atggtgagcg ctcacacctg gaggttcact acagttgatg
    61201 caccggaaga ggacggatca accgagttcc ccctctgggc gatggccttg atcatactgg
    61261 tcgccgccgg agtgataggg gtggtagtct accgcgtggt caagaaaccc tcaaagaagt
    61321 aaactatctt ctttcctaaa accgtcgagg gggcgctcga gcgaacgggc gcccctccgg
    61381 ccaccttttt tcaaccagaa ttcagcatcc cacacatcct acctgtctat caggcacctt
    61441 taagtattgt taagacaagg tgatactcat ggtcgaggta atcacaattg caggattcct
    61501 cgtcgcctgg ttggtctcaa ccttagtgat ctactttgtc actaaactat ttgggcagac
    61561 ggaagatatc ggaaaagcga taatggccgc tcttatcgga acggtcattt atgctctggc
    61621 ttacttttta tttgggaacg gactgctggc agcattagtg gcagggatcg tctggttatt
    61681 ggcgctgaga agcctgtaca agatcgattg gggcaaggca ctgatcatag ccataatcgt
    61741 ctggatagtg gcgctcgtga tcggtttctt cttaccgacc ctttccggtc cgttctaaaa
    61801 caatagaaaa ccttttagag gtcgaaaccg gccttattcc tatttttcca agcgagcatg
    61861 accgttctta tctgcttacc ttttgattcg gccattcatc tatgacagtg gccaggcacg
    61921 gcgcctcgtt cattttctta ccgaagcggt cgaaaagcct tccgttccgg atcgccacct
    61981 cgccgcttac cagcatcttg acggtctcta caagcagggg gacttccctc ttgacctccc
    62041 gggctcgtat ggccttagcc agatcatccc gtgagccgat atcctcccgt aggtcggaaa
    62101 tatcgaactg gtcataggcc accgtatcac cgcggtccag ctccggtgtg cacacgtgca
    62161 ccatcgaacc gtacgtcgcg tcatcgctct ccgccacccg gtggactatc tcttcccagg
    62221 ttccctgata ggtgttgggt aaggccgggt gcaggttgat gatctcgtgt ttaaggcagg
    62281 tctcggggtc taggatgagc atgtatccgg ccagcacccc gaagtccatg ggatgctccg
    62341 agatcttatc gcgcatggcc tttccgtaag cttcgcgcca ggcgttcagg tcctttccct
    62401 tcaggtcgtt acggaatccg tccgaaggca gtattatgac cgggatgcca tcctcctcgg
    62461 ccatggcgat cagcttggcc cggtgctggt ttccctttac ctcccggttc atgaacacga
    62521 acgatagctc agcatcgatc tccttgctct tgatcatgga cctcacggtg ctgaacagcc
    62581 caagggagcc gggccctctt ccggtggtga accagcctat gcgcttcatt tccatccctc
    62641 aatcccttgc taggagatat ttattcgcgc cccgggtcgg agcgttcctt gggcctcagt
    62701 gaggccacgt ggacggtcac agccactgct atcacaagga gcaggaccct tagccagtca
    62761 tcttcgatga agagcacggt cgtcagcccc atggtcagcc agagcatggc gatggtgaac
    62821 gctcgtacct tgatgggaag accctgtcct tcccggtagc tgcggatgta agagcctaac
    62881 agacgattgt tgatgagcca acaataaaag cgctgcgaac cgcgggcgta acaggcggca
    62941 gccaaaagta acaggggcgt ggtcggcagc accgggatga agatacccac caagcccagg
    63001 gacaggcaca gcgtgccggc cactatcagg gaccacctga ccaactttga ccccgattcg
    63061 cactcttctt tcatctgctc tcccgaaggt ccgaactcag aacctatcca acgtaccctt
    63121 gctcctggcc aggtattcga acccccggaa catcaggtat ccggcgatca tcacgatgaa
    63181 gccgaccagc gcctccatgc ccagcaatcc cgatagctct cccagggaag cgccctgcac
    63241 ggccatcctg gccgcctccg tcccgtaggt catcggtatg gcgtaggaga acggctgcag
    63301 atatcccgga aggaacgaga ccgggaagtt gaccccgcag agcagcagcc cgatgaacag
    63361 gaatatgttg gcgacgatca tggatgtgcg caggaacagt cccagcgagc tcagcatcag
    63421 tccgaagccg gtcatggcga aggtggtgac cagaatgacc gtcgccaggc ccaggtagtt
    63481 ggcctgggag aagtccacgt tgaagataag ggcggcgtaa aggaacgcta tggtgaccgt
    63541 ggccaatccg ttcacgatct ggaaggcggc tcttcccacg aagacggaga agcggttcgc
    63601 gggggacacc aacaggttct cgatggtccc ctggttcttc tcctccccgg tgatgttgca
    63661 caccgcgaac acgctcacgt aggccaggga ttgcagcgcg ttcccgatgg ccacgaactc
    63721 catggaaacc tcggaattgt tgacgaactt agcgacgtaa acgaagaagg caatctggaa
    63781 cagggacatg ccgaacagct gcatgatcca catggccggg ttcagccagg cgaatagcgc
    63841 ccgcttcgca agcaccgccg agctccagaa gacccgcaaa gggttgctga cgttttcgga
    63901 catatcagta cctcatcaga ttggcggtct tgcgcgcccg gtggtccacc gccttgtaca
    63961 gccagatgga gacggttagg tatagtacgg acaatatggc cagatacagg atgtcccccc
    64021 agtatccgac cgaaaaaccg tcagcgtaag cgggaagggc ggcgtacctt atggcgtcga
    64081 tgccccaggt cggtgccaga ctataggaaa ggggatgcga ccagtaaggc aaaaggaata
    64141 tcgggaacat gcttccagtg ccgacgtaga tagggaactc cagcccgttg gtgagcacct
    64201 gcgccgaacg cgtcagcacg aaggcggcgc tgaacagcat gcccagggtc gccaacgaga
    64261 gcaaggtcag cacgaaggcc agcatgaaca gccagaagtc ggccacctcc aatggggtct
    64321 ggaatatgac catggccgcc accaggacga agaggccgtt gactatgccg accagggcgt
    64381 tccagatggt cctcccgccg atgatccaga tgagcgggct aggcgcggag aatatggcat
    64441 ccaccgtacc ccaccagcga tcggactgta tggagaagcc ggaagcgtac agggtgttgc
    64501 cccacatgcc catcatgccc ccgcccagca ccgcgtacag caccgcttcc ggacttggtt
    64561 cctggtagag catgagcacc accatggcca ggacgaacgg ggcgatgatg ttcgggatga
    64621 tccactgcgg ctcggcccag aacatcgcgg cctggtgccg gaaggaagct gccgtcgcgc
    64681 gaagcctagg catcttccct caccagccag aggtaggcgt cctccaacgt gggttccttg
    64741 accttcatgc cgatgacctt gcggtcctcc agtaggtggg tgaccttcgg caataatgat
    64801 accggatcgc agacctgcac tcgcatggtc tgcttgtcct cggacatgtt ggcggtgacg
    64861 gtgcgaacgc cgtccaaggc cttcagcagg tccaggtcct tctcggtgat gccgaaacct
    64921 tccacctcga tgaccgaggt gtccttgacc agcgatttta gcttgcttgg ggtgtccaag
    64981 gccactatct ttcccctggt tataaccccg atacgatcgc agagctcgtc cgcctcgtac
    65041 atgtaatggg tggtgagcag gatggtctta ccctcggcta ccaggtcctt ggtcatgtcc
    65101 cgggcgtccc gggccgcctc cgggtcgagg ccaatggtca gctcgtccat gaatatcagc
    65161 tcgggatcgt ggatgatgcc cttggcgatg tgcagccgct gcttcattcc ccgggagtag
    65221 tcctccaccc gggtgtccgc cttgtccagg aggtttaccc tcttgagaac ttcctcgatg
    65281 cgcttgtcgc gtatggaaat gggaacgcca tagatgtcag cgaagtagcg gaggttctgc
    65341 cgggcggtaa ctcgataata gaggcctcgc tcgcctccga gaattagccc gatgcgcttc
    65401 cgcacctcca tggactcctt gaccacgtcg taaccgagta tcttcacgct accagatgtc
    65461 ggcagcagca gagtggtcag aaccttgatg gtggtggtct tgccggcgcc gttagggcct
    65521 aggaggccga acagctcgcc acgtcgtacc tggaaatcga tgtcgttcac cgccacggtc
    65581 tccttcttct tctgatgaag gatgccagtg gtgctgtggt atttccttac caagcccttg
    65641 acatcgatga cgatctcatc actatccatc tgacttcccc tttttcgtca ttccctgttc
    65701 ggtaataacc tttaccgtgg gcgataaaaa tgtttgcgca cgatgggacg aagggttagg
    65761 accatgacat cgaaaaagcg cctgacatat aatctccagg tctgtgataa ggccaatcag
    65821 ggtggatggt ctatcgatca gcgaagggga gctccgcaga agcggcaacg caggtcgccc
    65881 tcggcgttca ttcccccgca gtaatcgcag agcaatcttt cctcgttctt cctcagccgg
    65941 tcctcatggc tgacccgggt ctttctccaa atgaaccatg cggacagcat catcaggacg
    66001 gccacggcga tgaccaccag ggcgggaacg aggaaaccgt caacccccaa cccggccacc
    66061 agcaggaaga acaggcccat gaagagtatc attccgccta ccgaggccag gattatggcc
    66121 ggaagcggca cctgtggagg ttttggtctc tgttcggccg tctcctccac ttggtggagc
    66181 ttcggcatct ctctccggtc gctgctcccg ccgtacatcc cttcagacct cttcggccga
    66241 catgggttca agacgattta ttcgttgcta gttggtccat cacgttcggc gcgacggttt
    66301 ccatcacgct tatgagtccc taagtccgtt catcttttca gataccatga tgtccaagat
    66361 acccgtagaa ctaggggcac tgaaggccga tcatctggac cgcgagatac tccgaacggc
    66421 gatgatcgct gagctggacg cggtaagcct gtacgagcag ttggccgcca tgaccgccga
    66481 ccataagatc cgccggatac tgctggatgt ggccagggag gagaagaccc atgtggggga
    66541 gttccaggtc ctgctgctgc tcatcgatcc ggagcagagc gaggagctgg aagagggacg
    66601 aaaagaagtg gaggaagagc tgggctgacg cgccaggttg ggaaaggaag ttctcggctc
    66661 acttgtaccc gaacttgttg cggaacaagg tgagggaatc ggaaactatc tcagtggccc
    66721 gggcccgtcc ctgccagccg atgacgttgg tccccttctt ctcttccagc ctcttgtagg
    66781 tcttgaagaa ctcggagatc tcgtccagaa ggtgctgggg aatgtcctcc agctccaagt
    66841 actggttgtt gcgcgggtcg ccgcacgcga cggtaaggat cttgtcgtcc tgccccttct
    66901 cgtcgctcat ttccaggacc ccgaccggcc gggcctctac gacgcagcca gggaaggtcg
    66961 gctcgctgat gagcaccatg gcgtccaggg gatcgccgtc ctcgtaaaag gtgcgcggta
    67021 tgagcccata ggccaacggg aagacgacgc tggaatgcag cacgcggtcc agcagcatgc
    67081 agtcgaactc cttggacacc tcgtacttgt tcttgctgtc cttgggggtc tcgatgatga
    67141 cgttgacgat ctccgggggg ttgcgcccag aaggaaggtt cttccataat gacatttcaa
    67201 ttcctctcgg ccgcttcgat tgtctttagt tacttatctt ttttcccctg acacaaccgc
    67261 aggtattgat atcaaggacc ggcgagaagc atggtcggag cggacgaact aagctcatct
    67321 ggtagccccc tcagaaatta atataggacc tatggcatac tgtaacccga tgggagagga
    67381 ctacatacag accgtgctgt tccagctttt tataatcatc ttaatggtcg aagtggccag
    67441 gatgatctgc aacagggtca agatacccac ggtgatcggt gagatactgg tcggcataat
    67501 catcgccaac accttcctgt acaatttcat caacctaggc tcggaccggg aggtgttcga
    67561 ggtcctcaag gagctcggtg tcatattcct gctgttcacg gtcggtctgg agaccccgtt
    67621 cagctccata cgcaaggtgg gtaagaccgc catgttcgtg gcgaccttcg gggtcatcat
    67681 cccgttcttc gtgggttatg tcttcatgat cctgacctta ggtccggaga agcagctgga
    67741 atccatgttc gtaggggcgg ccatggtggc taccagtgtc ggcatcacgg cgcgagtgat
    67801 caaggacatg aacctcatgc aggccgtgga gtcccgggtc atcatcggtg ccgcagtcat
    67861 cgacgatgtc atgggcatga tcgtcctggc ggtcgtcgta ggtatcgcca gcggtggaag
    67921 cctggacatc atccaggtgg ctgccgtttc catacaggct gtgctgttcg tcctggccat
    67981 catattcatc ggttccctat tgctaccaaa gatggtcaag cagagggatg agaagaaagc
    68041 gaagcaagtg tgcaccgcgg accgcaagcg caagggattc ggcccgctgc cgctggccct
    68101 gatcgtctgt ttcgcgctgt cgtccatgtc cgcattcctt ggcctggccg cgataatcgg
    68161 tgccttcctg gccggcatgg ccttcgggga gttcaaggac aagtggccct gcgaggagaa
    68221 gatcgagccc atcaccgagt tcctgacccc gttcttcttc gtgttcgtag gcatagaggt
    68281 ctccctggcc gccttcgggg agttcgaggt tctgctcctt gccgtagcga tcaccgtact
    68341 ggccataatc accaagttca tcggctgcgg tctcggggcg aaaagcctgg gaggcaagtc
    68401 ggcggccatc atcggcgtgg gcatgatacc ccgaggtgag gtcggtctga tcgtggccag
    68461 catcggtttc gcaatgaagg acccgatcac cgggctgaac atcatagaac cagggcttta
    68521 caatgccata gtgttcatgt ccctgttcac cacgttgctt gccccgcccc tgttgacgta
    68581 cacgttccgt cggaaactgg gtaagaagtg cgaaatggtc ccgcccgata tagagtgatt
    68641 ttgagaaacg acttccccaa ccctatttag ttgtttatgt gggaaagagg gagctggcca
    68701 ccaccacgac ggcgatggtt atgacgcaca gcgcgatcac caggtagggg ctgagcttaa
    68761 gggccttctc atcctcgtta tcgaaatacc tgatgaggcc cgccgcggac tggaatcccc
    68821 cggtcttgtt atccttcgcc atgtcgatcg cacctgctac ctccaaaagg atataaaaga
    68881 attatgcccc cgcaccgtcc tcctttccag gcacccaacc gcgataaacc ttataatggg
    68941 caggggactt cacggcttga tagcatgcat tgggcagacg tgatagctaa cacccttatc
    69001 gaaaggggcg gtaagcatct gatatctact ggcatcaccc cctccggctc catacacgtc
    69061 ggcagtctgc gggagtccat caccgccaac gcggtctaca aggcgctcaa ggacaaaggg
    69121 gccgacgtcg acttcatcta tctggtcgat tcctacgatc cgctgcgaaa gcgctacccc
    69181 ttccttccgg aatgcttcga gaaggaggta gggaagccga tatgctacat cccttgcccg
    69241 gacggctgcc acgcttccta cgccgagcat tacatcactc ccttcctgaa cgccataggc
    69301 gagctgggca tcaagccccg catcatatgg actcacaagc tctacgagga agggaagttc
    69361 accgagatcg tggacctggt gctcagggaa aggtccaagg tcggccaaat actcggcgag
    69421 gtcaccggcc gcaagatgcc cgagaacttc tggcccttca gcgccgaatg tccgaagtgc
    69481 ggaatgttca gcgacaagat cagcggttac gatttcccgt acgtgcactt caaatgtcac
    69541 tgtggctacg agggggacgc cgacattcgc aagggggagg gaaagatgcc ctggcgcgtc
    69601 gaatggcccg ccaagtggaa gctgttcggg gtcacctgcg aaccattcgg caaggaccac
    69661 gccgccgccg gaggttcata cgacagcggg gtgcgcctgt gccgggagat atacggcgtc
    69721 gagccgcctc atccagttcc ctacgagttc atccagttca aaggaaaggg gcagatgcac
    69781 aagtccaccg gcaacgtggt caccggtacc gacgcgctgc tcatcacccc cgccccggtg
    69841 ctggccttca gcgttcttcg ctataatccg gaacgacaca tcgactacga cccggggatg
    69901 ggaatactgg acatcgtcga cgagttcgac aaggtggaag cctactactt caatggcggg
    69961 gcggacgaga aggagaagga cctgttgcgg gcgtacgaga tagcgcagcc ctcggctgtc
    70021 cgctccaagt tacccttgca ggtcccctac cgacacctgg tgagcgtggc ccaggtatcc
    70081 gattccttcg agagcgcggt caaggtcctg cggcgttcca tggacctgcc tgacatatcc
    70141 acggaggaca tggaggtcct ggaccaaagg ctgaactgcg ttcgccactg gctgaacgcc
    70201 ttcgcccccg aggaggtcct gtacaccgtc agccaggaga ggccagacgt ggagatcacc
    70261 gacgaggaac gggcctacat ctccgtgctc cgggagcggc tggcggaaac ggagtgggtc
    70321 ggtgagttgg tacacaacgc catcttcaac accgccaagg agctgggaat gcagcccaag
    70381 gtgtgcttcc tggcactgta ccggctgttc ataaacaggc gctccgggcc aaggctaggg
    70441 ttcttccttt ccaccctgga ccgggacttc gtgctgaaga ggctttccga agcctgaaac
    70501 gcaggtcacc tcttcttcaa ggtgaacagg atcacagcga tccccaacca aacgaggaag
    70561 ccgataacca ggaacagcac gttccccggg taggcgtagt taatggccca tatggccccg
    70621 aaggccacca ggagcgtgcc ccagaacatc aggaagttgc cgtcgttgct gcgcctcctt
    70681 tccagagcac cgctgcgctg cttgaaccct acgaaagtgg cgaacatccc tcccaggagc
    70741 agcatggacg gtatgaacag cgtccaatcc ctaactatcc aggcgatcag tatggccgcc
    70801 gcggtggcga ttatgaggta cgaggccgtc aaactggtca gggtgaccga ggctctatcg
    70861 ttcatttcac ttcaggtgaa aaaggaaggc cggtattatc aaacttgccc tcgttcactc
    70921 gcgtaacacc ttctctgggc cgtttcggca gtagaaggag tacttcaatc ccagatcgtc
    70981 cgtcaccttg cataccgggc agtcgcaggt cttggccggc atctcacagc cgacgctctt
    71041 gcccaggtag cagtacagaa gctcccggtt actggcgttg cactccgtat acgtagcgca
    71101 gcccggacag cggcaagttc ccttcgcggc ctcgatccaa cgttccagct cctccggtcg
    71161 cagggcgtct aagcgcctta tctccgattc gaagcggtcc atgatatcgc caatatcact
    71221 agcgggcgga gggcatataa tcgttatctg tcctagcgca gcactcccat gttggtcagc
    71281 ttctccggca ggtacttgtc ggtgacgaag tccaatccgt atttggccag ggcctgctgt
    71341 tcggccttct tgttcagctt gagcatggtc tcgatctcac cgcgccagta ctcgtcggcg
    71401 aagcgggggt ccttgagctc agcgtgcaaa gcccgtatgt ccatgtccgt cagcttgtcg
    71461 gtcggcagct tgtagttcgt gatatcggaa gcggtgatgc ccacgaactc ggcggtcggt
    71521 gtggccagat actccgagat gtgtgcggtc ttgatcgcgc cgtacgccac ggaggcgaat
    71581 atgcggaagg accagggatc gccgtcggtg aatactacca ctggcagcct catctcctcg
    71641 ttcatgcgct tgatgatgcg gcgggtggaa cgagcaggtt gtcctttcag atgcaccagc
    71701 acggcattgt acttgtcatc gaagccgttc tccaccagcc tatcgaacat accaccagtt
    71761 tcgatggcca ccacgaactt ggcgttggtg ctgatcaact gcagcttctc cttctccacg
    71821 ttgttcggga tgccgtaacc ggaatcgccc acgtcgtccc ggcagttgat ggtcttcaac
    71881 cgtcccttgc ggtccatctc gcttatggtg atgtccccga tgatgctggc cccgttctct
    71941 tccggccgca gcttgaagtc ctcgcgcaag caggcggtca cgatctccag gtcctctgcc
    72001 agcatgttgc tctcgtcctg cgagttgaac ttcgcctttt cccagccctc ggagatatag
    72061 tacatctccc tcagggtgga ggacttctta tccgcgatca tatcctccag gaactccagc
    72121 acgtacatgg tgcgcaacag catcaaggcc ccattgacct tcttcgcgga acgggcgccc
    72181 gtggccttgc cgtacttgaa caccccgtgc ttggggtcga atcgaatgtt gctcttggtc
    72241 ctcaggggca aggtcatctt cggtatcttt ccggtatcga tctgatcgta gatcgactgg
    72301 gctatctcct tcagggagct gaccgcctta ttctcttcct cagtcatcgt taagcgcctc
    72361 cgtggactcg tcgtaatcga cctcttcgtc ctcatcctcg accaccggcg cctcatcgct
    72421 ctcggtgatc tgcagcccct tcaggtccca atcacctggt aacggctcag ctccgattat
    72481 gaacaccgga ttgatgcccg aggcgtagat ctcgttctca tcgtaatcgt ccttgttcag
    72541 gccgttcagc gagaagttga tctccaatcg ttccgtggac gctatcttgg gtagttccca
    72601 ggataccttg ccgtcctcgc gtacctccga gggaaagaac tgcagcccct tgtaatcgaa
    72661 cgatccgggc ggcagcacca tgtgcaggtt gaacttctgc gattgcggcg tatagttgta
    72721 aatggacact cgcacccgtt gatgtccttt ctcgaacgta accgcgtcat cgatccagac
    72781 cacgttcatg atcttggtta tgcttccgct gagcttgggt atcggtttac cgacgatctt
    72841 agcgctcttc tgggcgatga gcggcagtat ctcctgcacg atctcgaact tgaccttggt
    72901 cttgctcttg gtctccctct tgttgaggtg cgtcttcaac gagcggccgc atatcttcag
    72961 ggccagctcg atctccgcct gtagctccgg aagattggct atggcctcct tggcctcgga
    73021 ggtgaacggt accttcgtgg atgccacatg caccaatatt atcgccgggc cgaacggtat
    73081 gccggaccct ccgcgctgct ccaggccgta tcgtctccag tcggtgttct cgatggcctt
    73141 ggtgatcacg cacgccccct gctgatagag caaaggcacg cggttggcga acctcaggat
    73201 ctggacctgg gagtccttcg ccaagcctcc tccgtagacg atccccacct ctatcaggaa
    73261 gggattcccg gaatgcacct tggggtctct ggtcaccggt ggggcgtaga actccggacg
    73321 gacctcgtca aggacgttgc gcagcccctt cttgatcaga ttggcgccta tcggcgaaag
    73381 gcagtcggtg ggcggggcca ttatcttcac cgcggcgatg gccgccagca gtgccttctg
    73441 ctggtccagg ctgagcttgg ccgggttgac ctccatgctc aggccggcct tgtcgcagat
    73501 ctctttggcc aggcggtcgc ttattcgtga aaagtccagt tgcaggaact tgcccagggt
    73561 cttgttcttg gtgtccttgg acatgttcat caatgttcca agctccagtc ccgacgggtg
    73621 gggcttgatc tccttggtgg ccgggggcat cttgtccgtg gccctttcga aggtggtgcg
    73681 ctttccatcc ggatctacga aggttatctt ggaatgcggg ttcacgatgg cggtctgctt
    73741 gaggtattcc atcaccgact gcttgccgcc gacgtaacgg ccgttcatgt ggtaggtgat
    73801 cttcgtcccg tgctccttcc cgtcccagat gaacgggtcc tccttcagca cgtcgggcat
    73861 gttcttcttg gtgttgacca ttatctccat gcgccaggcc acgtcctcca ctccggtctt
    73921 ggagacgacc accgccggct tcccggtggt gatctgcccg tacatgaccg tggccgatat
    73981 cccgatgccc tgctggcctc gggactggcg cacggcgtgg aaacgagagc cgtataggag
    74041 acgcccaaag acgttgggga tggccttctt gacgatgccc ggtccgttat cctcgacggt
    74101 gacccggaac tcatccttgt ccaccctctc caccatgacc acgacatcgg ggagaattcc
    74161 ggcttcctcg caggcgtcca gggaattgtc caccgcctcc tttatgccca tgatgagcga
    74221 cttgatctgg gagtcgaagc ccaatatgtg ccggtttcgt tcgaagaact cggagaccga
    74281 tatctccttc tgctttttcg ccagttcgtc agctatagaa gacattggac catcccttca
    74341 tagaaaagac cgattgcatc ccggggtgca tatccccggg agcggtaaaa aggttttgtg
    74401 tttttagagc ttctttccgc agttccagca cttggtgtcg gacttcagta gcttcgccga
    74461 gcactgcggg cagctcagtt cgtcatcgtc gaacttggcg ccgcaggacg ggcacttatt
    74521 ggcctcgccg ggaacctcag tgccgcagtc ggagcagacg aacttctcct ccttggcatc
    74581 cttcaccttc ttgtccttgg tctgggcccg cttctgctcc atctcgaaga tcttcttctt
    74641 ggagcggtcc atccaccagg tcagcagtat cagtatgtag aacagcacgg ccatgctgta
    74701 gaacgagtag accgtcccgg acatcaggga gttggtgagc accttgctca gctcggcgtt
    74761 caccggaccg aaggtctgcg gggtagtggt ccaagcggtg ccgttgacga cgccgtactg
    74821 gaaatagtag acgccttcct ccaggctggt cacgttgtac aaatagaccg cccctagcga
    74881 ggtgctgtgg gagtagtcca tggtgtaatt gggattgtcc tccggctcgc cccaattgtt
    74941 gaacaggagc aggctcacgt tggcgttggt atctcccgcg gtcagcacca cgctgaactg
    75001 caactggtca ccaggctcgg tatgggacgg tgaaacggtc cctccgacca gcaggctgtt
    75061 cttggagctc acgtcctgca cctcatagtt ggccacagtg ctatacaagg cgcctcccag
    75121 agaaagtccg attaccagga acaacaccag tccgaacact gccagcctct tgcgttcctt
    75181 tagcccgaag taggtcggta tgtaataggc gagcagggcc acaaggatag gtagtaggca
    75241 gaccacctgg gctagccaga gctgcacggt cagggtaagg gagacggtga ccaagagggc
    75301 cagcgccatg cccacccaga tagacatctt ggactgccgc acccccttcg tcatctcatt
    75361 tatatcgccg atgaaagaca tcggccggcc ataattattg tatctttaaa cactttcgtt
    75421 aggaccatgg cagaaatgag gccgggggaa ggcaggatgg ccgttctggc cctgggcggc
    75481 aacgccatac tcaaggccgg ccaggaggcc agggacgacg tgcagatcgc caacctccag
    75541 gtggccttcc gctccatgct gcccctgctt gaccgttacc cccgaatgat gatcacccac
    75601 ggcaacggtc ctcaggtcgg gaacatcctg ctgcggaacg agctgtgcca tacggaggtg
    75661 ccgcccatgc ctctggacgt ctgcgtcgcg gaatcgcagg gacagatagc gtacctggcg
    75721 atgcaggcct gggaccgggc ctgccgttcg gcgtgcaggg aggtccccat gcttccgatc
    75781 atcacccgca ccgtggtctc ggcggacgat ctggccttcc gggaccccac gaagcccgtg
    75841 ggaccttatt attcgaagga gagggcgctc gtcctggcga gggagaaggg atgggtcttc
    75901 cgggaggatg tcaagagggg tggcatgcgt cgggtggtcc cgtccccgga cgtggtcaag
    75961 gtggccaagg aagaacattt acgaacgcta gtcgaatcac ttacccctcc tttcgtggtg
    76021 ctgtgcggag ggggcggagg tgtcccggtg gtcctaagcg gggctggtct catcggcgtg
    76081 gaggcggtgg tggacaagga cctcgcatcg gccagattgg ccgaggtgtt gcatgccgat
    76141 attttaataa tggtgaccga tgttgagtcg gtctatctgg atttcacgag cgaaaggccg
    76201 cgtcctctcc gtaaggtgac ggccaaagaa ctgagccgcc acgccgcgga gggccagttc
    76261 cccctagggt ccatgggacc caaggtcgag gcggcgacca ggttcgtgaa ggccaccggt
    76321 agaaaggcga tcatcacttc cgccgaccgg ttgatggatg ccctggacgg aaaggcgggc
    76381 accacagtgg agtgaggaaa agcaaagatg gcctcgacga tcgaagatca gataaaggcg
    76441 atccaggaag agatcgacaa gacccagaag aacaaggcca ccgaatacca catcgggaag
    76501 ctgaaggcca agatagccaa gctgaaggag gatgtggaaa agcggaggtc ttccagcgga
    76561 ggccctgcca agggttactc ggtaaagaag agcgggaacg ccaccgtcgc gctcgtgggt
    76621 ttcccgagtg tcggaaagtc cactttactc aataccctga ccggggcgag gagcgaggtc
    76681 ggcgcttacg acttcaccac cctggatgta gttccgggcg cttacgagta catgggggcc
    76741 aagatacagg tcctggacat gcccggcctg atacgggacg cctctaaggg caagggccgc
    76801 ggcagagagg tcatctccgt ggtccgcgcc tcggacctgg tgcttttcgt tctggacttc
    76861 tacgatacca acctgcaggt gctggtccgg gagctggaga acgccgggat gcgcatcaac
    76921 acccatcccc cggacgtggt gatcgccaag agggacctcg gcggaatcga catcaagacc
    76981 accgtcaagc tgaccaagct ggacctggac ctggccaagg ccatgatcat ggagttcggg
    77041 atggtgaacg ccgatgtggt catccgcgag gacatcgacc aggaccagct ggtggatgtc
    77101 ctggccggga accgcattta cataaacgcc gtgctggcca tcaacaagat cgatatctcg
    77161 gacgcggaat acctcaagga ggtccgcaag aagttcaaac actgggaccc ggtcttcatc
    77221 tccgcggtca agaacatagg tatagacgag ctcaaggccc ggatattcga taggttagag
    77281 ctaattcgag tctacatgaa gaagcaggga gaggacgccg atctggacgt gccgatgatc
    77341 accaagcacg gtgccacggt cggcgatgtc tgcgactcca tgcaccgtgt tttcaggcag
    77401 aacttccgct acgccctggt ctggggaaag agcgccaggt tccccggtca gatggtcggt
    77461 ctggagcatc gtctggcaga cggagacgtc ctatcggtca tcattcgccg caccggcgag
    77521 tgaagggata acgattaaac gcctcccagg gaatgtccgg ccgatgtcaa ggaaaggaat
    77581 gtccacccgc tccgtgcacg acggagacaa gtccctgcat tacgaagggg cgatcaacac
    77641 cccgatattc caaagcacca ccttcgcctt ccctaccgag gaaccgcgca cctggaacgg
    77701 ggagatcccc gacggcacct acatctattc gcgggacagc aaccccaccg tgagagcggt
    77761 cgaggataag ctggcctccc tggagggcgc ggagtcgtcc ctggccttct cctcgggaat
    77821 ggcggccata acctcagcgc tgctgacctt cctgcagaag ggagaccgtc tggtcgccat
    77881 gcaggacctc tatggaggca cttacgcctt ccttaagaac gagatgtccc gcctaggcgt
    77941 ggacgtcacc ttcgtaccga ccactgaccc ggcggagcta tgcgcggcga tagacggcag
    78001 gacaaaggtg ctctacctgg agagcccgac gaatccgctg ctcaagctca tcgacatccg
    78061 cgagacgtgc agattggcgc accagaaggg gtgtctggtc atgatcgata acacctttgc
    78121 cactcccatc ctgcagcggc cgctggaact gggcgcggac atcgttctac acagcgccac
    78181 caagtacctc aacggccact cggacgtcat cgccggcttc gtggccggat ccaggaagga
    78241 catggcgatg gtccacctga gacggaagct gtacggcgga gtgctggacc cattgccggc
    78301 gtatctgctg ggcaggggca tgaggaccct ggacctgagg atgcgtaagc atgattcgaa
    78361 cgccttggcc gtggccaggt tcctggagtc ccataccaag gtgtccaagt gcatccatcc
    78421 cgggttggcg tcacatccgg accacgagct ggcgaatagg cagatggacg gatacggggg
    78481 aatggtgacc ttcgaggtga agggcgggcg agcggctgct gaaagggcgc tgaagcggtt
    78541 caagatcatc gccaaggcgg ccagtctggg cggcgtggag tcgctggcaa gcatgccggt
    78601 gaacacctct cacacctctt acagttccga ggaacggcag aagctgggca tcggggaagg
    78661 gatgatccgt ctctcggtgg gcatcgagga ccccgaagac ctctgccagg acctggacca
    78721 ggccttgaac taatcgatga tggcctggac gaatatctcc gaggacaggc cccattcgcg
    78781 caccatctcc tcggccgcgt caaggcagtc gaagggcacc agcagcatga ccacatctcc
    78841 ccggtaggcg tagctcatgg cccgggagaa catctgatcg tccttctcca acgattcgca
    78901 gagccatatc tctcctacca gccggcggcc gtccttgcgg gtggcgacta tatcggggac
    78961 atgctctccg taacctcgcg gtttgatggg gaacgattcc aggttcacct gcagatcgga
    79021 aaagcccttg cggtccaggt cgtccgccca ggcctgcaac agccgcgcct tgcgtcgccg
    79081 gtcgtcctcg tccaacatag cgccctggct atgatctaga tcgttattca tacttgcgct
    79141 gggtcatccc tcgcaatatt tattatcgtc cgttccttct cacgccacat gatccaaagg
    79201 ccccggggga ccagggattt cggcccggag gagatggagg tacgccgcca cttcgaggac
    79261 atgatgcgcc aggaggcggt cctgcacggt ttcagggaga tcgctacgcc catcttcgag
    79321 cataccgagc tattcactct caagtccggt cccggggtga tcgaggagat atatgccttc
    79381 caggacaagg gaggccgcga gatatgctta cggccggaac tgaccgcctc ggtggtccgc
    79441 ttcttcgtca gcgatctggc gacgctaccc cgaccgttga agatgttcta cttcggacag
    79501 tgcttccgtt acgagaggcc gcaggccgga cgctatcggg agttcttcca gttcggggcg
    79561 gagataatcg ggaacgccac gccggagacg gacgccgaag ccatcgggct ggcggcggcc
    79621 atactggaaa ggaccggtct ccaggattat cgtatacgag taggtcacat cggcatactt
    79681 agggagatgc tggcgcaggc cggggtctcc ggagatcagg cttcgccgat cctgcagaaa
    79741 ttggacaaga agatataccc ggaagcggag gagctgatgg cgcaggccgg catcgatccc
    79801 caggtggccc aggatataat atccaccacc aaggtcaccg gtcccgtgtc cgtgctggat
    79861 tcccgggaag gcccggccag cgattacatc cgccaagtgt gcgatatact gttggccatg
    79921 gggttcgaca acgtcagcgt ggacctcggc gtggtcaggg gtttggccta ctacaccggc
    79981 atggtgttcg aggtggacgc gccgaagcta ggggcggaga agcagatatg cggaggtggc
    80041 tcctattctc tctcggaact gttcggcggc gagaaggtgt tctccaccgg gttcgccatc
    80101 ggcttcgatc gtaccttatt ggctctgcag acggaaggcg tgcatttcga aagaccgggc
    80161 ataaccgcgt tcgtggttcc cgtgggcgac agcgtcagga gcaaggcctt cgagatagtg
    80221 gccgaactgc gccgctccgg catctccgcc gacgtggacc tgatgagaag aggggtcggc
    80281 aagagcctga agttcgcggc caccgttccc agcaagtacg ccttgatcat aggggaaaag
    80341 gagatggaaa gcggttccgt caccttgcgg gacatgaaca gcggcgagca gtccctggtc
    80401 aagatggatg agctggtcgc aaaattaggg cgttgagggg cttcagggcc ggagtttgtg
    80461 gggatcacaa gggaggattg aacttaggag gaaaacgcct ccggcccctg acgccttgaa
    80521 ccgtgcattt agcatcgtat atataatgat ttgtgtgctg caatgaggtt atgtaggagt
    80581 taacgccgca gctgcctagc taggttatgc tgatccaacg tccagttgac cagggcgtcc
    80641 gccttggtta tgacctcgtt ctcccggggc acgtgatgga ccttcaccgt tctcattccg
    80701 gtcaggatgt ccaccgcttc tcggttcagg ggcgccaggt tgggggcctt gacccggtat
    80761 tgccccttga gctgtttgat caccagctcg gagtccatga aaacctcgac ctcgctcgcc
    80821 cctcgtctca gcagctcctt cagcccggcc agcagcccat ggtattccgc ctcgttattg
    80881 gtcatcactc ccaaataatt ggagccggag gctatctcct gtccgtcctg atcgcggatg
    80941 atgtaggcgt aggcagagtc cccagggttt ccgcgggacc ctccgtcggt gaacagctgg
    81001 aacttcatcg ttccccgtat ggtctaggtt attaatccca cctggtatgc gaaaccttga
    81061 caatgtgcga aaatataccc tcccacgtcg ttttacggca aggacgtcga tagcatggac
    81121 cgagagacca tagcccgggt ggccaaggtg gctaggctga acctcaccga ggaggagatg
    81181 gagagatacg ccaaggacct ggacgacatc ctgaatagct tctcggtcct ggacgaggct
    81241 ccggccggcg atacttacag cttcaacccc atcccggtgg tcgacgtgct tcgtgaggac
    81301 gagccaggtc aggacctcga cccgcaggtg ctgagggacc agatggggac ctacgagggt
    81361 ttcgtaaggg ggcctagact gtcttgagcg ccatttacga tcttatccgt tacgcccagc
    81421 ttaagcaccg ggcgttcacc gaaatagtgg aagatctgga cgatactaag ttccacttct
    81481 cggccaagga caacctgtgc gccgacggtt tccaggcgcg ggcggggtcc gccgtcctgg
    81541 acggataccg gccgccgttc gacgccaccc ccatacgcaa aatgaaggat tccggcggtc
    81601 agctggtcgg gaagaccacc atggacgagt tcgggttcgg gaccttcagt acgaactccg
    81661 cgcacggcgt tccgctgaac cccttcgacc tggagcgtag ctgcggcggt tcttccggcg
    81721 gcgcgggagc ggcggcctgc ctaatacccg gccacatcgc ccttggggtt tcgactggag
    81781 gttccatatc cggtcccgcc tccttctgcg gcgtggtagg cctcactccg acgtacggcc
    81841 gcgtttcccg ttacgggctc atagattacg gcaactccct ggacaaggta gggctcctct
    81901 cccgttcatc ttcattggtg gccaagcatt tccggaccat ctccggtccg gaccccaagg
    81961 atcccacctc ctgcgcccag ccggtcctgg ctgatagagg aaagatgccc cgttcgttag
    82021 cggtacccaa ggaggcgctg cagaacctgg acccggccgt tcgttcatcg ttccaggacg
    82081 cgctctctag gttcaaggaa ctgggaacgg aagtacatga ggtatcaatg ccctcattgc
    82141 gcttcgccct tcccgcctat tacatactgg cgacctcgga ggcgtccacg aacttggccc
    82201 gttattgcgg catgcgcttc ggtcgtaggg aagaggagct caaccagcac ttcaacgact
    82261 tcttcaccgg cgtccgatcg gaaagctttg gcgacgaagc gaagagaagg atactactgg
    82321 gaacgttctg ccgcatggtc ggcttccgct ctcgttacta tctcaaatcg ctggcggtgc
    82381 gccagctgct gatcgaagag tatcagaagg tcttccggga ccacgatgcg gtcgtcaccc
    82441 cgaccatgcc cttcatcgcc cctcgcttcg aggagatagg cagaatgaag accttggaga
    82501 tgtacggggc cgacgttctc accgttccgc cgaacctcac cggtatgccg cacatatccg
    82561 tcccttgcgc ttacgttaaa ggattgccgg tcggcatgca gctggtggcc gaccattgga
    82621 aggagctgga cctgctggaa gcggcctccg cctgggagaa ggcgttcatc taccgattcc
    82681 cggaggtgtc gccatgaaga tcggactgga gatgcacttc caactgccca cccggtccaa
    82741 gctgttctgt tcctgtccca cctcgtccgc ggaaccgaac cacaacgtgt gcccggtctg
    82801 cctgggttat cccggctcaa ggccttcgct gaaccgtaaa gctctggaag ctgggttggg
    82861 catcgcccgc ttcctggact gtaagatcga ggaaaaggtg tggttcaacc ggaagaccta
    82921 cttctatccg gacctgccga agaacttcca gatcacccag tacgaatcgc ccctgggcac
    82981 gaacggtcat ttcgatctca acggaaggcg catcggcatc tggcgcgttc atctcgagga
    83041 ggaccccggc cggataaggc gggtcggccg ctccggagag gagatagcgt tcgtcgatta
    83101 taaccggtcc ggcataccgc tggtggagat agtcaccgct cccgatttga cctccccgga
    83161 ggaggcccgg gagttcatcg accagctggt caccgaactg cgatcgctct gcggcctgga
    83221 ggcccaggac gagcagtcgt tcagggtgga tgccaacatc tccctgggcg aggagcgcgt
    83281 ggaggtcaag aacgtccagg ggctgcgcaa cctggagagg gccctaaagt tcgaggctag
    83341 caggcaatcc aagctcctgg ccgccggtaa gaaggtggtc agggagaccc gccgcttcga
    83401 cgaggagagg aaggtcacct cctccgcccg ggagaaggag accgaggagg attacggtta
    83461 tatcggcgag ccggacctgg gcgagttccg catcggggaa atggcccgga acctggacct
    83521 gaaggagacg ccgttggtgc gtgccagacg ccttgtctca tcctttggga tcggtgaggc
    83581 gacggccaag cagctggtcc ttacttccgt tacgctcact gacctgttcg aggaactgtg
    83641 ccgccacgtg ccgccggaga aggcggtctc ctggaccacc ggtcccatct caagcaattg
    83701 ggcggttctg caggacccgg gcaagtggcc ggagatcgtc cagatcgtca aggacgattc
    83761 tgacggacgc atcaacgata acgaggcgaa gcgccggata ttatcgttgg caggggtaca
    83821 gcaagaggct gccgtcgaag gaggggacga catgacgaaa ttgatatccg atttcgtgga
    83881 ctcccatccg gaggtcctgg cagactatcg caagaacccc aaggcggcca acatggtcat
    83941 cggacacgtc atgaaggaga gcaagggccg ctactcatca aaagaggtcg tggaagaggt
    84001 tagaaaggaa atggataaaa gggtttagtt ctcctcgtcc tcgtcggcca ggctgagcag
    84061 ctgcagctcg gagagcttgg catcctccac cttggtgggc gcgccgtcca ccagggactg
    84121 gaacttcttg ttcttcggga acgcgatgac gtcacgaatg ctctcgcagc ccaggagcat
    84181 ggcgcatagg cggtccatgc ccattccaat tccgccgtgc gggggcgctc cgaactccaa
    84241 cgcctcgagg aagaagtcga actccctctg gatggtcgcc tcgtccattc ccagtatgcc
    84301 gaacaccttg cgctgcattt caggatcgtg gttcctaagc gaaccggagc cgatctcgct
    84361 tccgtcgaac accaggtcgt acgagtggcc catgcccttg gcgcattcct tgccctccgg
    84421 gatgacatcg cccaccggcc tcacgaaggg gtggtggaag gacgtgaggc caccggtggc
    84481 cgggtccttc tggaacagcg ggcaggatac caaccagacg aactggtgcc ccttgccttc
    84541 cagcagcccg aggtccctgg ccaatttcag gcgcaactgt cctccggcct tgagcacgct
    84601 ttccctggga ccggccaggt acagcaggag atcgccgagc tgagcgccgg tgcgcttggc
    84661 gatggaatcg cgaacttcct ctgggaaata cttcacgatg ttggagctca aaccttcgga
    84721 ggtcatgcgc atccaggtga ggccgcccat gccctgggac ttggcccact cgatgagccg
    84781 gtcgacctgc ttgcgcccga cggaaccgtc ggtgtcctgc tccttgatca ggttcgcctt
    84841 caggttgatg caggtgacca tgccaccctt ggaaaggacc ttctggaata tctcatatgg
    84901 agcgtccttc accaggtcgg tcacctcctc catctccagt ccgaagcgga catccggagc
    84961 gtcggtgccg tacttggcca gggcatcctt gaggtcgatg cgcgggaaag gtgtctggag
    85021 cttctcgttg aacagatcct tccagaccga ggcgtacatg ccctccacca tgttcaggat
    85081 gtcatccatc tccacgaacg acatttccat atcaagttgg gtgaactccg gttggcggtc
    85141 ggcccggctg tcctcatccc ggaagcagcg ggcgatctgg aagtaacgtt ccactccgcc
    85201 gaccatcaac atctgcttgt agagctgcgg cgactgcggc aaagcgtaga actgcccggg
    85261 catcgttcgt gacggaacca ggaagtccct ggccccctcc ttgctgctgc gggtcagcat
    85321 tggcgtctcc acctcgatga acccctgcgt ctccaggtat cggcgggcgg aggatatcag
    85381 cttggagcgg aacctgaggt tggcgctcat ctccttccgg cgcaggtcca ggtaacggta
    85441 cttcagccgg aggtcctcac cagggagctg ggagttcttc tgctcggcca cctcgaacgg
    85501 gatgggcttg gagcggctga gtatcctcgc gtcctcaatg agcagctcga cctccccggt
    85561 gaggttgcgg gcgtcgttgg ttccttccac tcggttccga acgataccag tgacggtcac
    85621 gacgaactcg cgaccgatat tattcaaaat tttctccaac cggtccaagt ccccgctgtt
    85681 ggaggcctca gggtcgaaca ccgcctgggt gctcccatga gagtccgcta tgtcgtagaa
    85741 cagaactcct ccatggtccc tgtagaacct tacccaaccg gcgagggtag ctctcttgcc
    85801 aaggtcccct ttcgtcagtt gtccgcaatg gtgtgtcctt aacatttcca ttcctctggt
    85861 tggatatggt cggtaagccg gagtaatgtg gatgccatat taaattcttg tccaccgcgg
    85921 aaatggcaaa acgccaacta atgacaatta aagtcactat tatcgttcaa attgccagga
    85981 tatataaacg aaggtggacg gtttgaccca ttacttctgc tccaccgggc tgaaatcagg
    86041 caaaaagttg aacgggtcct ttatcacgtt caagatgacg taggtgttgg tcttcttgac
    86101 cccctttatc gtcagcatgg atttgaccac ttggctgaac tcctcgcggg agcggcaggc
    86161 cacccaggcg atggaatcgc attcgcccgt aacgtctaga acggcgacca cgttcttcag
    86221 ttccttgatg ctctgctgga cgcttatgag gtcaccttcc acgtagatgt gcacgatggc
    86281 catgaactca tagcccagtt tcatgtagtc cacgttggcc cgatagccgc ggaccacgtc
    86341 gtggctctcc aagttgcgca cgcgttgtat cagggtggtg ggatgtatgc ccagcctttt
    86401 ggcgatggct ctagacgatc cctggctgga tttgcacaac tcctcgatga tccgcttgtc
    86461 caattcgtcg agcatgatta aagccctatt accaatttcc agaacggcct ccttagatat
    86521 atgtctttca agactaggga tgaggtgctc atttgtctag ttcatctcta tataagctcg
    86581 gcgtggacta tttacacgaa ttaagctatc cacaggtcat gaccgtcaag ctttacgagg
    86641 ccgaccctta ccttaacgag ttcatcgcca ccgtgaccaa ggtggatggg gactgggtcg
    86701 tcctggaccg aactgccttc tannnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    86761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    86821 nnataatcgc cgccggagcg gaggtcacct gccagcacgt tgaccgtgag aacatggtgg
    86881 agggtggtcc gcgtgttaaa ttggatagga taagtgacag aatggtacgg gtggtcagca
    86941 tcggcgagca cgacagcgct gcctgcgccg gcgttcattt aaggaacgcc agggaggtag
    87001 ggatgctgct ggtcagcaaa ttcacctcgg ccaagcccgc cggggactgg gagatagagt
    87061 tccaagtagg tccggaggcg atccgaacgg cggtggacca ttccgttcgg tccctgatgt
    87121 tggccgagcg gatgggtgcg ctgcctcagg acagtctcac cgccttcgac aaccgggaac
    87181 gggaacttgt cagggcgagg gaagccctga aggtgtacgg gaagatggcg ctatcgtcgc
    87241 tcaagccaga gaggctgggg gaatggaact actattccgg ggccttcact ggcctggacc
    87301 ggaagttggt gatggaaaag gcgaacgaga tggtggccgc cggaagttcc gtggccgcgc
    87361 tcgtatgcca ggatgacaag accttcctgg tgctcgcatg ttcaacggat gtcaagttgg
    87421 attgcgtatc tattctgaac tccgtactat ccaatcatgg tggaagaggg ggcggtaaac
    87481 cgaacttcgc cagcggtggc acccctggcc agatcgagcc acacgttctg ctcgataaga
    87541 tatctctact gctcaaaaat agatgatatt ctagaaaata tattcaattg tatagtttaa
    87601 ccataataaa ctgtacaaat gtattgatat tgaatgtata gatgcacatt tgttgcctag
    87661 aaagttattt aatatatgtt gttgtaaccc ctttccaatg cctaccaaca agaacttcga
    87721 tgagatgaag gaagacatct taaagaaggt gaagaaggag aacgtcaagt tcgtcgagat
    87781 gcagttctcg gacatactgg gcaccgtgaa gagcgtgtcc atccccacca cccgggtgga
    87841 gaacgtcatc gatgacgggg tgttccttga cggctcctcg atattggggt acgcgaccat
    87901 agaggaatcc gacatgaggg ccaaccccat cctggattcc ttccagatat acccttggat
    87961 cgactccggg gtaaagaccg cccgcttcat gtgcaccata tccgaccaca gcggcaaccg
    88021 cttcaagggc gatccccgct gggccctgga gaagatggtg gagaaggtca aggagatggg
    88081 ctacgacttc aacgtcggtc cagagttcga gttcttcatg ttccccatga aggatggagt
    88141 tccggtccct gtccccgccg acgccggcgg atacttcgac ctgatgcccc aggacaaggg
    88201 cgagatcgcc aggaaggaga tggtcctggc cttcgatgag ctgggctatg acatggaggc
    88261 ggcgcaccac gaggtggcgc ctggccaact ggagatcgac cttcgctaca acaacgcctt
    88321 gaccatggcg gaccgcatgt tgaccctgaa gtacggtgtc aaatgcatcg ctcagaagca
    88381 cgggatgtac gccagcttca tgcccaagcc cctgtacggt gagaacggtt ccgggatgca
    88441 cgttcacatg tccctctcga acaaggagaa gaacgccttc tacgaccctg aggggaagtg
    88501 gggacttagc gacatggcca tgaactacat gggcgggctg ctggcccatg ccccatcaaa
    88561 ctgcgccata ctcgcctcgc acgtcaactc ctacaagagg ctggttcctg gttacgaggc
    88621 tccgtgctac atctcctggg ccaacatgaa ccgcagcgcc ctgctcaggg tgcctgccgg
    88681 tcgcggaatg cgcaccaggg tggagcagag gaaccccgat ccggccggaa acccgtacct
    88741 acagttcgcg gtgatgctgg cggccggtct ggatggtata aagaacaaga tcaaccccgg
    88801 cgaaccgatc gagaaggaca tctatcatat gtccccggag gagcgccgtc ggaacaagat
    88861 cgtggacctg cccatggacc tcggggaggc gctcgacgtg ttcgcggaga gcaaggtcat
    88921 gaaggaggcc ctaggggagc atatcttcaa ccactacctg tacatcaagc accgggagtg
    88981 ggacgactac cgcactcacg tcaccgactg ggagatccag cggtacctca gggtcctgtg
    89041 atgtgatctc ataaatccct tccaaacctc ttcctaaacc tttttccgtt ctgtattcaa
    89101 tgctcgttca tgtgcggccg cttctccctc ggcctggtct atggtttttc cacccgtttc
    89161 ggggtgcctg aggtaccgga gctgaagccc cgttacaaca tcgccccctt ccagcaggtc
    89221 ccgatagtcg tgggtgggga ggccaagagc gtcaagtgga tgagatgggg cctggtgccg
    89281 cactgggcca agggggagga gttcggtctg aagttaatca acgtccgttc cgaatcggcc
    89341 atggataagc cgatgttcaa gacgctcctg aaccaccaga gatgcttggt tcccgccacc
    89401 ggattctacg aatggcagag gcaagggaac cggaaacggc cataccatat ccgggtcaag
    89461 gggcaggagc acttcgccat ggccggcatc tacgacgcgt ggtccaacgg ggaaaaggac
    89521 ctggtgacct tctccatact caccactgcg gcgaacgaag cgatatcgcc gatacatgac
    89581 cgcatgccgg tgatcttgcg ccgtgaacgg gaaggggagt gggcatccag ggaggcgctc
    89641 tccgctgaca cgctctccga ggcgttccaa ccactacccg cttcgatgat cgacgcctat
    89701 ccagtctccg atatggtcaa cgattcccgc gccgatcatc cggacatggt cgtgcctcag
    89761 cgaacgcagc aggccacctt gttctgatgg ccgccgtgaa aatcccaacg gtttttatac
    89821 cggcaggaat aatccgtcga acgatctcat gatgccagga atgggtaggg gcgtcaatcc
    89881 gcgccagatg aagcaggcca tgaagcgcat gggcatttct caggaggaga tgcagggcgt
    89941 ggaggaggtc atcattagga ccgccgacaa ggagtacgtc ataaaggatg cggcggtcac
    90001 ctgcgtcacc atgcagggtc agaagaccta tcaggtggtc ggggacccgg aggtccgttc
    90061 ccgtcaagcg accaagccgg aggatcccgg gatacctgag gaggacgttc agctggtgat
    90121 gtcccagacc ggtgtgagca aggataaggc cgtgcaggcg ctgaaggagt gcgacgggca
    90181 gccggccgag gccattttaa agataatgtc cgggtgaaca tcatgtgtct agctatgcca
    90241 gccaaggtat tgtcgatcgt cggcgacgag gccgaggtgg acttcggcgg tgcaatacgc
    90301 aagaccaacg tgtccatggt ggacgctaag gtcggggagt atgtcatcat acacgccggc
    90361 ttcgccatcc agaaggtcga cgaggaagag gccaaggaaa cgctccagct gtggaacgag
    90421 ttcctggaca gcaccgagta acccttcaca aacatttatg tgctttatcc ttccctagag
    90481 accaccagga acgcttatga ggatcgttta cgggccgatc aggtccctgg gcttggggag
    90541 ggtggtggcg gtcgatccga taggccgctc gcccaaggtc tgcaacctca actgcatcta
    90601 ttgtcatctg ggatgcggcg gcatggttct tttcgagagg tcggaattca tagatgacgc
    90661 ttcggtactg gatcagatcg gggaatgtct gcaccgtgag gagtgtgagt cggtcatgtt
    90721 caaagggacc ggagagacgc ttctggccag gaacatattc cacatggcca agatgctccg
    90781 tgaaggttcg gacaagaagg tggcgctgtt caccaacagt accctgctga acgaccccga
    90841 gatattggag cagctggatg cgttcgacat aatcatcgcc aagttggacg ccgccagcga
    90901 ggagaagttc caaaccgtta ataggcctca tccctccatt agattccagg acgtcctcga
    90961 gggaataaag aaggccaggg aaagttttgc tgggtcgttc cgattgcacg tgacagtggt
    91021 ccgggagaac ctctcggaca tcgataacat ctctcagata tgccgcgaga tctgccccga
    91081 ctatgtttac ctggaaagcc cggagggatg cgacccttcc cataccgtct gcaagaagga
    91141 catgcaggca gcgatggacc gcttcttcgg gataaggtgc gtcagctcgc aggataagga
    91201 atagaaaata agaggaaagg aaaaggttta gttcagttct tgcagagctt caggagcgac
    91261 tcccacttct tgtccacgtt ggcctggagc tcgtccgcga ccccggtgaa cttgcctttc
    91321 atcaggtgtt tgaagcggcc ctgagaggtc agccattccg ataccggctt cttctccctg
    91381 tttccctcgg cgatgcgcag cgactctccg gtcagcctcc agaccccgtt ctcatactcg
    91441 tacagaggcc agacgcaagt ttccaccgcc agcttggaca aggcgatggt ctgcgagcct
    91501 tcatgtctcc agccgcgcgg gcatggcgat atgacgttta tgaaggccgg tcccggggta
    91561 tcgatgccct tcttggactt ctcgatgagg tccttccagt tgtgcggcga ggcctgggcg
    91621 gcataaggca ggtcgtgggc gattatgatc ctggtgaggt ccttggggaa ctccttcttg
    91681 ccgggaacgc aagtgccggc cgggcaggtg gtggtggacg ctcccttctg agtagctccg
    91741 ctcctctgga tgccggtgtt catgtacgcc tcgttgttga agcacacata taggaaatcg
    91801 tgcccgcgtt cgatagcccc ggacagggac tggaatccga tgtcgtaggt cgccccgtcg
    91861 ccaccgaagg cgatgaactt gacctcttgg tccagcttgc cctggcgctt cagcgagttg
    91921 taggcggcct caacgccgct catggtagcc ggtgcgttct cgaaggcggt gtgtatccac
    91981 ggcacgttcc aggaagtgaa cggatatatg ctggtcgaga cctcgaaaca tccggtggcg
    92041 ttggccacta caactggctt gtcggtcgcc ataagcacct ggcgggcgat gatcggctcg
    92101 gcgcaaccgg cgcagaggcg atgtccttcg accaaccggt cctcagtgtg gctcaggctc
    92161 ttgaggttca caacctcacc cccaggtagt ttacgcgctc tccctttccg gtcatgatct
    92221 cctcaaagac ggtgttgagc tggccgggca tgatgtccct tcctcccagt ccgtagatgt
    92281 agttgctgat caccggcgcg tccttcatcc gggaaacgga tgactgaacg tccatgtaca
    92341 gcggggcgcc ggtgccgggg ctcatggccc tatccagcac ggccacggcc ttctttccct
    92401 tcaggaactt ggccatgtcc tcggacggga acggacggaa catgcgtacc ttgacggctc
    92461 cgaccttctt gccctgggcc cgcatctggt ccaccacgta gcggacggtg ccggcggtgg
    92521 agcccatggc caccatcaga tattcggcat cctcggtgcg gtacccctcg accagatcgt
    92581 acttccggcc agtgagctcg gcgaactcct tcatcacctg gcgggcgaca tccatggcgt
    92641 tcatcatggc ggtcactatc tggtacttta tctcgtaata gtactcgggc atggcgatcg
    92701 gcccgtaggt ggtaggcgtc ttgacgtcca gcaacggtct caggggctga tacggtccta
    92761 cgaacgcttt caccttctca tcctccagta gctcgaatcg ttctagagcg tgggtgatga
    92821 tgaagccgtc caggcaggtc attatcggta accgcacttt catgttctcg gcgatgcgga
    92881 aggccatcag ggtgttgtcg taggcctcct gaacgttctc accgaatatc tgcagccatc
    92941 ccgaatcacg tccgcccatg gcgtcgctgt ggtcgcagtg gatgttgatc ggtccgctga
    93001 gagtgcggtt cgccacggcc atgacgatcg gcgttctcat ggatgcggat acgtacagca
    93061 tctcccacat gaaggccagt ccggcggatg ctgtcgcggt cgccactcgg gcaccggcgg
    93121 cggacgaacc gacgcatatg ctcagggcac tatgctcaga ttcggcgcaa acgtattcgg
    93181 tgtccaccaa tccatcggcg acgaactccg agtaggcttc gactatgatc gtctgagggg
    93241 tgatcggata ggatgccacc acgtccgggt tgatctgctt ccaggccatt gctatggcca
    93301 tatctccgtt gactgccatc ggttcgctca ttccactccc tcctccttca tggtaatcgc
    93361 cttcaccggg cactggttgg cgcaaatgcc gcaacccttg cagtgggtgt acttgaaacc
    93421 gaccatcttc tcgttctcga cgatgatgct gttgtcgggg cagtatatcc agcaggtgag
    93481 gcagttggtg cacttcttct tgtccacctc tgggcgctcg gagcgccatt ccccggtctt
    93541 gtacttcttg gagctgccag cctcagttat catgccgcca gcagctaagg aactagatgt
    93601 gttttcggcc attcactgca cctcctcata ggctctcttg atggcccgca ggttcttctc
    93661 caccacgtcc ttgctcagct tgccggacat cttgttcctc atctcatcga tgatggtgtc
    93721 gatgccgacc acgttggtga ccttgaccaa ggcgcctagc atggcggtgt tggtcatggg
    93781 ccttccgatc tcctccaaag cgatcttggt ggcgttgacg gcgtagacgt tctcgctgcg
    93841 tccgactgca tgtatcagtt tggacttctc gtcagggaag ttggcaatga tcgcccctcc
    93901 ttccttcagc ccctcgacca cctttccagc cttaagaagc gtggcgtcga tgattaggac
    93961 gacatcgggg aagtagacct ggctgtgcac cattatcggc tcgtccgaaa tgcgagcgaa
    94021 ggcgcgaatg ggcgcaccca tacgctctgg cccgaactcc gggaaggcct tgatgtactt
    94081 gccctccttg agggcagcac tagccaaaat ctcgttcgcc gtgacgaccc cttggccacc
    94141 ccttccatgc catctgatct caatggtgct cacagcatct cctctcacgg taatccctct
    94201 aaatagttgt aatataaaat catttcagaa aattgtttac gaaacgcaca gtaaaatggg
    94261 atgaaatctt cgaaaatacg agttacgcac atcgtttgcg gaatcatcgt tgtcctaacc
    94321 gattttatta agcattataa gataaccacc ctgctacacc ttctcattcc gtaggaaatt
    94381 ccttttggaa tcaattttta caggggctcc aacgaggcac gaaaaggtta aaattatcat
    94441 tttttacaag atcggttctg ggaaaacgat gctggcaacc atttaatgtt gaaaagaaag
    94501 gtacgaacgt acacggaata ttacgatagg actcgcacag cacttagaaa aattaataga
    94561 ctccacgcct attttccatt cgggttagga cattgaaggg ccatcggccc cctctgaact
    94621 tgcctgcatc gaacgttctt agagtggtgg aacaacccat gaaaaggata gtgagcatat
    94681 ctgacctagg caagaacgac attgacatcg ccggtggcaa aggtgccaat ctaggggaac
    94741 tggtagcggc cggtttcaac gtccctcccg gttttgttct gaccaccgcg gcatacgatc
    94801 atttcatgga ggccagcaag atcggggagc gcgtccacga actgttggcg aaggtcgacg
    94861 ccagttctga gaggtcccta caggaagcat cggtcaagat cagggagctc ttcgataccg
    94921 tcgagatacc ggcggacctc aaggagcagg tgctcacctc ccataaggcc atgttcaagg
    94981 gcaagaagat gggtctggta gcggtacgct ctagcgccac cgcggaggac cttccgacgg
    95041 cgagcttcgc cggccagcag gatacctacc tcaacgtgga gagccccgag gaactgcttg
    95101 acaaggtccg caagtgctgg tcctcattgt acacaccgcg tgccatctac taccgcgtca
    95161 ccaagggctt cgagcattcc aaggtaaagc tggcggtcgt ggtccagaag atgataaact
    95221 ccgagatatc cggtatcatg ttcacggtcg atcctaactc ggagatgccc cacatcatca
    95281 tcgaggccgg ctacggtcta ggtgaggcat tggtcggtgg caaggtaact cctgatacgt
    95341 acgtggtgga caagttccac gacaagatac tcaacaaacg catcgccaag cagacctgga
    95401 agctggtgcg cggcggtgat ggcgagtgtg agaaggccga cgttcccgag gagttgcgca
    95461 acgcccagaa gatgaccgac gagcagatat tggcccttgg cgagataggc cgcaacatcg
    95521 aggcccatta cgatcgtccc atggacatcg agtggtgcat agaggagagg gtcatgtaca
    95581 tcgtgcaggc ccgtccggtc accacgctct catccggggc caaggccaac ggcaaggtcc
    95641 aggaccacgg gctggggcag agcgccaaga ttctgctgaa gggactgggc gcctcgcccg
    95701 gcatggcggc aggtccggtc cgcatcgtcg ccgaggagat gaacctggag gtggtcaaga
    95761 agggtgatgt gatggtcacc gccatgacct ccccggacat ggtcccggcc atgacccgcg
    95821 ccgcggcgat agtcaccgac gaaggtggga tgacctgcca cgccgcgatt gtagctcgtg
    95881 aacttggaat tccatgcatc gttggcgcat cgcatgccac cgagctgttg aaggacgacg
    95941 agaagatcac cgtggacgga agcatgggcg tggtctacga agggatagca gcccccaaga
    96001 aagaggagaa ggcaccggtc gccgtggcag cagccgtacc ggtgaccggc accaaggtgt
    96061 acgtgaacct ggcgatccca cagaaggccg aggaggtatc caagctcccg gtctccggcg
    96121 taggcctcat gcgcatcgag ttcctgttca cctcctacat ccaggagcac ccctgcgcgc
    96181 tcatcgagaa aggtgagtcg aagttcctgg tcgacaagct tgcggatggc atagccatgg
    96241 tcgccaaggc cttttacccg cgcccggtca tcctgcgcac ctcggacttc aagaccaacg
    96301 agtaccgtga tatggagggc ggggagaagt tcgagccgca cgaggagaac cccatgatcg
    96361 gctggcgcgg ctgttcccgt tacgtgtccg actcgtaccg tgaggccttt aaactagagc
    96421 ttaaggccat caagaaggtc cgcgaggaga tgggtctgaa gaacctgcat gtcatgctgc
    96481 cgttcgtccg caccatcgac gaagttcgca agataaccgc catgatgaag gaggtcggcc
    96541 tggagcgcaa ccgtgacttc aagctgtatc tgatggctga gatcccctgc aacatattca
    96601 tggccgagga gttcgccgag tggtgcgatg ggttcagcat cggttcgaac gatctgaccc
    96661 agctcaccat gggggcggac cgcgattccg acgttctggg aaagatgggc tacttcgatg
    96721 agcggaacga ggcgataaag agggccatca acatcctgat cgaggcggcg caccgcaaag
    96781 gatgcaccgt gggcatatgc gggcaagctc cgtccgtcta cccggagttc accgagttcc
    96841 tggtgaaggc tggaatagac accataagcc tgaacccgga caccgtggtg gccaccatca
    96901 ataccatcgc ctcggccgag aagcgcatat tgctggaagc ggctcggaag acccttaagt
    96961 aaaacctttt caaggctcgc tcttcagcag cctggtggtt atctccacca ggggatggtg
    97021 cgagccatct attatcttca catcgtccag ggtgtacagt ccctgttctt cggcgctctt
    97081 ctccaggcca agttcgacgt ctctcgaggg ctccagaacg aacgccgaga actgcttcac
    97141 gcccatctgc ttcgacgcca gagcgcgatg gtgcccgtcc accagtatat agttctcgtt
    97201 gttctgtatg acgatgatcg gctcgaccag gccgcgcttg atctcctcct tgcggcccag
    97261 gagctcgtcg gcgtagacct ccttctgggt cggacgcaac gattccacgg gaacgatgcg
    97321 tctacgaacc atgatggaaa cgccgtgctt ggtctccagg aagttcttga tcatggcgac
    97381 cttgttaggc gtagcccttt cgatgtgtga acgaacgatg tccaggttgg aaattattcc
    97441 gagcagcgtg ccgttttcat ttatgaccgg cacgttccta aggccgtaac ggaaaaggat
    97501 gcgggcggcg tcgtccaggt ccattttagg gttgacggtg accgtgccct tccgaattat
    97561 gtcggataag ggcatgtccg gagtctggta gtttcgcaga agctccttag cggttatgaa
    97621 cccgaccagc tttccatccc tggtgaccgg catcccgtgg aactcgctgg ataccagagt
    97681 atccacggcc tgcctgacgg tgaagtccaa aggcacgtgg accacatcac ggatcatgta
    97741 gtcctcaact ttcagcttcc gttcggccat gtgatcctcc aatctaaccg ctgtcctcga
    97801 ttaatacttt gtcaggctcc tcacggattc actatttcac agccatcttc caatgtcagt
    97861 tcctatcgtt gcaggtatgt tccagaattt tactggcgag tgcccgatcg caacgtgcca
    97921 gtatctccgg ggcacctaag gattaaatat tacaagacga taaggggaaa ggccgtaagc
    97981 cccggtagtg tagcggccta tcatgaagcc ctgtcgaggc ttcgactcgg gttcaaatcc
    98041 cgaccggggc gcttttatca tcttctcctg aagaacagcg ccgctgcgat cgcggccaac
    98101 gccaacattc ccacgccaac catccaacgc caattcgacg gatgtggacg agttcccgct
    98161 gacgttgtat tcccgataca cgcgcgatgt cgatctcacg ttcgaggtac ccccgtcccc
    98221 gaagttccat gcccaggaga cgaccgctcc gtctgggtcc gtgctcatgg attggatagt
    98281 ttagatcaac aagctcaacg gatcttcgga atgacctcgt caaagagata gtccatccgc
    98341 ttgtggaact catcctgttg gaccttccac ttgcgattga gcccggagtc ctgcaagaga
    98401 tgcatacctt ctggattcaa cggaaaagaa ccagaaacgg tgcacacggc tatgctccag
    98461 atccgccgag ccgcgtctat cgaatagccg cccccgccgg tgaccagata ccggccgtcg
    98521 caatgctcgt gcgccagcct atgggttatc tcggccacct tctcgtaggt tcgggtggtc
    98581 agtcccatcc ccaccatctg gtcgctgtag tgggcgtcgg tcccgaactg atggattatg
    98641 atctctggac ggtacgcttc caaggcggcc gatagcacct tgtcataggt aggggcgtag
    98701 acctcgtcag gagtgcagcg cggcagcggc acgttgatgg cgtatccttc cccgtcgtcc
    98761 tccccgaagt cggagaccgc cccggtgcct ggatagaacc ccgctccgta gcggtggaag
    98821 gagatggtca gtatcttctc gccgttgaat atggactggg tgccgtcgcc gtgatgcccg
    98881 tctatgtcga ttatggctat gcgctcgtaa ccgaacctgc gctgcaagcg tctcgcggcg
    98941 atcgccagat cgttgaagac gctgaagccc gccgcatggt ccgcccgagc gtggtgaagg
    99001 cctccgcccg gcgtcatgac gtggtcgtac tccccccggg cgatgctctc cgctccatgc
    99061 aaggtgcagc ccaccgcggc cagcgcgcct tcgaagaggc catggcacac cggggtgtcg
    99121 cccatgtcca gatacccggt cccgctggcg ctcatctcct tcacgttctc gatcaatgat
    99181 cggtcgtgca cctctctgag gtcctcttcc gtggccgaag gtgattccac gtactccagg
    99241 cggccatcga atacgtcaag ctccctcagg gcgtccctga tgatcttgaa acggatgggc
    99301 tggtatggat gctctggccc gaactgatac ctgagcagat catcgttgta gaagaaggct
    99361 gtggtaccgc acatcaggaa tccttatcca ttggccttcc atctttaggt acgacggata
    99421 cctaataact tttcccatct caatcgaaaa aatgaatgga aatagggcct tccttgatcg
    99481 ccaggcgctt ggatatcatc ccggcctcca cccagcaggc gttcattacc gctattggta
    99541 ccaggcaggt gggggtcagg atgccgtcct cggccgcggt catgatcttg gagccacgtt
    99601 gctcgttgat gtcctccatg gtgatggcgc ccaatcgttc cgcatagttc attacgttgg
    99661 agcagtccga ttctatgtga accttcaggc ggtcctcgcc gtccatctcg gcggtgaccc
    99721 aggtctcgtg cgaacagatg ggagtgacca gctttaccct ggaagccatg atgatagcga
    99781 aggggcgatt tggtataatt ttctttcatg gatattgcca aggtcgtagt ccacgatgct
    99841 tccgaattat tgagggcatt gatggccagc acatggtcgt atgtaaaaat tctatccgta
    99901 ttacgaattg gataatactt tatactctga taatattact aaagatgccc aagtaatagg
    99961 tgctatcatg agataccaga gagctatcat cacgctgatg gtcttggccc tgctgaccgt
   100021 cgcggtaccg ttcaacgccc aaggagaaac aacgagcgaa cagagcatta gcatcaccga
   100081 ctcgcgtggg gtcaccacca atctgaccgg tccggcggtg catgtcgcct ctttcggggc
   100141 gttcgccacc aacaccctgg tggacatcgg gatgctggac aaggccgtga tctttgacgc
   100201 tacctctgag ttcaacaaga gcgccattcc cgaaatggaa ggtgtcagtg ccaatcattt
   100261 cgtcaccgtt agctcatcca acaaggacgt ggtggtgcaa accatgctcg atctggtaga
   100321 cgcgggtaaa tggaacaaga gcagcgacgt ggtcctcggt tacggctact cctacctgaa
   100381 cacggtctgg gctgatctcc aaggatatga attcaaggtt gtcacattct acccgaactc
   100441 ctacaatggc atcgtccagg ttgtgaagga catcgagacc ctgaccgggg cgaaccacag
   100501 cgtttccgcg gaaatgacct acgtcaggga ttacatcgca aatactctgg aggaaaacgg
   100561 tatcgataac gatacggaac gggtgaccgc cctttatgtc agttacagca gtgagacctt
   100621 gaagatcggc aacaacggct cggtgacggt cgacttcata aactacgccg gcggcctgaa
   100681 ccttggtgag aacccggaca aggccctgcc cacctacacc gccgacttct cggctctcct
   100741 ccaattgaac ccggagttcg tactgctgga cggttactat gccggttcgg ccggagattt
   100801 caaggcgctg atcaacgacg aagatgtcac ggtgtataag ctgaacaagt cctggaactc
   100861 ctactgcccc gacgccaccg atggcctttg gacggtcgcc tgcctgttct acccggacta
   100921 cttccaaggg gagctgccag tggatgctgg tgacacggga gatggacagg acaataccat
   100981 gatctacgcc ggggtcggcg tagcggttat agtggtggct atcgccgcgg ttctcctgat
   101041 gagaaggaag aattagggcc ctatgtcctc cttccaaacc attttatcgt tcctttcttt
   101101 gaggtgaggt agcatggaca gcgtcgcaaa gcgtaagaga cggaccacgg cggtcttcgc
   101161 ggggctgttc atagtgcttt tcattttcat gatattggac ctcgcccagg ccttcatccc
   101221 gcttacattc gaagaggcct tctgggcctt gctcggccgg ggaacggaaa cgcatcagat
   101281 catcatctgg aagatgaacc tgccccgggt ggtcatggcc atcctggtcg gggccgggct
   101341 gggtatcgct ggggcggtaa tgcaagcgat tttccgcaac cccatggcct ccccttacat
   101401 cctgggacta tcgtccggcg cttcactggg ggcggccatc ggcctgacgt tcgccgtgac
   101461 ctggcttccg cagctgctga tggttccgct attggcattc gccttctgca tggccaccct
   101521 gttcctggtg tactacatat ccaacgtggg gggaaaggtg cccacggaaa cgctgctgct
   101581 ggccggtatc gctgtaggat cgcttctctc cgccctggtc tcccttctca cctatatggc
   101641 aggggagcag atgcagggca tcgtttattg gaccatgggt aacctgacca acgccaattg
   101701 ggagaacatc atgatcgtgg cgccattgat ctttgctggg agcctgatca tggtcgccag
   101761 ctctcgcgac ttgaacgcca tgatgctggg cgacgcgcac gcgttggacc tgggcgtgga
   101821 ggtcaagaag gtccgcctgc agctgctcat cgcctcggcg ttggtgaccg ccgccgccgt
   101881 ttcgttcgtc ggcgtcatcg gcttcgtcgg cctggtcgta ccgcacatat tacgaattct
   101941 tatgggtccg gacaaccggg cgctgctacc cgcctccatc gtgggagggg cggccttcct
   102001 gatgatgtgc gactacctgt ccagggtcat cgcccccaac atcggcattc tgccaatagg
   102061 cataatcacc gccctcatcg gcgccccgta cttcatctac ctgttgcgca gaaggcgcag
   102121 cgaagtgggg tgggactgat gctcacggtc gagggaataa gcttctccta tcgggaaaaa
   102181 ccggtgcttc agaacgtgga cctcgaggtc aagaaaggcg agatcatcgg tatcctaggc
   102241 cccaatggct gcggtaagac caccttgctc aagatactga accgtaacct gaaaccgcag
   102301 aaggggcgcg tcctcatgga gggcatggac ctggaggaga tgtccaagag gaagatcgcc
   102361 aggcagatag cggtggtccc acagtccaac gagatacgct tcgccttcac cgtccgcgac
   102421 atagttagca tggggcgcat gcctttcctt ggccagttcc agggcgagtc cggggatgac
   102481 atgcgcatag tcgaggaggc catggagaag acgagcatct cggagttcgc tgaccggccc
   102541 ataaatacca tgagcggagg cgaacggcaa cgggtgatca tcgcccgcgc cctggcccag
   102601 agacccgagg tcatccttct tgacgaaccg acgctgcacc tggacatcaa tcatcagttc
   102661 gaggtgctgg acctcgtcag gcgtctatcg caggaggagg gtctcaccgt ggtcatcgta
   102721 tctcatgacc tccccatggt cgtgaagtac tgccaccgga tggtcctcat ccacgaccat
   102781 aaggtgcacg ccctgggcac tcctcaggag gtgctaacgc cggagaacat gcgtgtcgtg
   102841 ttcaacatcg acgccgtgct ggagcacgat atggtgctca acgctccagc ggtcaagata
   102901 atcggttcct gcaatcgccg ctgaccccgt ccaaagatga atttgcaggg cgagcttatc
   102961 agggaaagtt tcaatagggt gcttttcttg cgtagtcgta tgcgacagct cctgagggga
   103021 aagatacacc gggccacggt caccgccgcg gaaccggact acgtggggag catcgtcatc
   103081 gaccaggacc ttctggaacg ggcggacatc tggcccgggg agaaggttct agtttcggac
   103141 gttaacaacg ccgcccgctt cgagacctat gcggtcgtcg gtaagcgggg ctcgggggtc
   103201 atcagcgtga acggcgccgc cgctcacctg gtgaacgtag gcgataaggt cataatcatg
   103261 gccttcgagc ttaccgacag acccatcccg tccaaggtcg tgctggtcga ccagaacaat
   103321 cattttattc gcaacctctg aggactggcc cctttaaaga aagctttatc tccaaccatc
   103381 taatactctc ggataaggga aaaccaatgg caaccgtgga tttcgacaag ttgatgaagg
   103441 acggctatcg actgatggaa gaaggcgaat actctaaggc ccttaccaag ttcgatgcgg
   103501 ccatcaaggc cgatccgacc aacccctcag catttttggc gaaagcggac gctggagtac
   103561 tggtccccaa ggtcactcag gaggagatcg tggccctata caagaaggcc tccgagctcg
   103621 atccggagaa ccctttcatc ttgcagagct ggggagcctt ctgcatggac atcggcctct
   103681 tcaacgacgc cgaggcgtgc tacaacaagg cggcccagat cgacccggag aacgccactt
   103741 actactattc ggagttcggc gtcgagtacc acaagaaggc gctcatcgtt tacgagtccc
   103801 gtctggacga gcagaccagg gccatcatag ccaagaaggc cttgaagtac ctgctcaagt
   103861 ccattgacct tgacgaggcc tcggccaaga agctactctg atcattgcag aagatgcctt
   103921 tccggcccgt cccggcgtaa gcgctcgttc ttacgttccg gggaacattg gtcgcacagg
   103981 cgtccatgcg tgtcataatg cgacggacat accagtcggc cgcacatggt gcaactgtac
   104041 ctggccggcc tggagcatat ggagcagaga cctatgacct ccatgctttt tcattgtccg
   104101 ggctagtaaa aataggttct ctcagatgag ccccagggag atcaatccct cgcggacgcc
   104161 ctcggcatgc ttgcccttcg ttaccaggtc cgccgccttt ctggccttat ccgaggcgtt
   104221 gcctaccgcc accccgtaac cgcactcctt cagcatcagg gcgtcgttgt cagcgtcccc
   104281 gaaggccacc acctccgata cgtcaactcc gatcaactcg caggctttac gaacgccagc
   104341 catcttgctg tgccccctct gcatcaggtg tatggcgaaa ccggtggcct ccacctctaa
   104401 tggccaatcc cttagggctt ccagcacctc cgtcaggtcg gcctcgcggt tcactccgac
   104461 ctcagtgcgc ctccattggt ccgtgaatag gcgacgtaca ccgggcatca cggtgcgcag
   104521 gtgctcgtac gcttgcaacg ggacctcgtt ggagaacagg gtgtgcacct cgtcctgata
   104581 ggagacgata ccgccgttct cggccaccac cgggcctcgc agaccgatga aggtagaaag
   104641 cccgtagacc actggcagaa cgttcccgct ggccagtatc accacccggc cgcggtcctg
   104701 ggcctttcgc agcacctcga tccccagggt ctgaataatc ttggagggat cggtgatggt
   104761 gccgtccaca tcgcacacca ccgccctata tcccatgtct acaccaggtc gctgcgcagc
   104821 tcgccgaggg tggtcaccct ctcggccacg gcgttgtgct tgtggatgga ctcctcgctc
   104881 tcgctgcgaa ccgtcaccac ggtgtcgtca ggcagttgcg ggtagcgctt gagtatcaag
   104941 gccagattgt cccggaccac atcctccacg aacttggggt tgcggtgggc gttgatcacc
   105001 acgttggcct cctccttccg cttcaggatc tcaaaggtgg ggctggagaa cgaggcctcc
   105061 acgatctcga tgagatcgtc gacctccacg tcgaactcct ctgggacctc cagcatggcg
   105121 gtggtcacgt tcctctggtt gtgagagatg gtcggaaggc atccgacctg cttcagggtg
   105181 tttccctgga tctcgtccac gctctccatg gcgcaggggc aggcggtcat tccgatcacc
   105241 cgggcgccga tcatcttcaa aagtccatcg ccgcgcttgt gagtggcccg agcgatgagc
   105301 ttgtaggatt cgatgctctt gcggccggtg ggcaaggagc gctctaaaaa gtaatctcct
   105361 ttgatgtgca cctcggcgta ggaggcgtac tcatgccggt ccagcagcct gcggcatatg
   105421 tcggaggcca gaacttccaa cccctttatc ggttgggaaa ctccctgctc cactatctcc
   105481 gcgatgacct ctaggttccg ggataggtga gatccccttt gagttgaggg caggtccacg
   105541 taaacatcga tctcgcaggt gaggcaggtg tcgcggccgt cacggtgcac gcgaaccggc
   105601 ttcttgaccc cggtcactcc cacccgggta agcttgaacc cattggtcag gtaccggttc
   105661 tgaacgtcgc tcttggaaat tcacatcacc gcttcctcca acggggggat atctttatat
   105721 tttagcccat caacaacttt tttggtaaaa gtatgttttt ctggtggaat gtcgttcaac
   105781 attgataaat aaccaggaca aaatccccct ctgatgatat gtggccttga tgaggctggc
   105841 cggggaccgg tcatgggtcc tctggtcgtc gccgcggtga tggtggagga cgaccgtctg
   105901 ttccgggagt ggggggtcaa ggactccaag cttcacaagc ccgaggaaag ggaaaggctg
   105961 gccgagctta tacaggccaa ttccacctgg aaggtggtca tgatcgatcc tggctccatc
   106021 gacgagcgca aagggacgac gtccctgaac accctggaga tacgggcctt cgccgctctg
   106081 atcgacgatc tgcggcccca gatagcatac gtggacgctt gcgacgccag tgagcagcac
   106141 ttcaagaccg ctctggctag ggcctgccga tttcgaacgg aactgatctg cgagcacaag
   106201 gccgacctga actatccggt ggtatccgcc gcctccatcg tggccaaggt ccgtcgggac
   106261 gcggagatgc gccgcatcgg agaggagatc ggcgaggtcg gcagcggtta ttcgtccgat
   106321 cctagaacga gggctttcct ggaaaattgg ataagggaga agggggattt gccaccatat
   106381 accaggaggt cgtgggccac ggccaaggac atgttatgct cctccaagac ctccaaacta
   106441 agcgactggg aatgacatga ccaccaagga ccacctattg aacgccattg acaagttcaa
   106501 cggcaagatg caatgcgatg cccagctccg cgaggaggta gggccgttag tgaagaaggt
   106561 caacatagaa ctgggcacgg agaactattc gttcctgctt aaggacagtt gcatctcctg
   106621 cttggacgaa ggtctgatgg aatgtcccga catcgtcgtc tgctcggacc cccggaccat
   106681 cgatgagctc ttcaccggca aaatgaagcc gatgaaggcc tgggccctgc gcaaggtagt
   106741 catcagaggt tcgctcgagg acgtcatgaa gctgcgcaag ttcttctgaa ccagccatca
   106801 gccgcaggta gaaaggttta taaccggcct acgcatgatg gggaaatacc agagcggggt
   106861 agggtagcca ggacatcccg tcgggctcat aacccggaga ccggtcgttc aaatcgaccc
   106921 cccgctactt tttacatctc tcaacttcca tatacgaact cctccattcc ttttcgcagg
   106981 atcaaatgcg taaggatgtt ctcgtcatag ggggaggtgc caccggggcg ggcatcgcta
   107041 gggacctcgc tcagcgcggg gtggaatgcc tcctgctgga gatgggggac tattgtcacg
   107101 gcgccagcgg cggcaatcac ggacttttgc acagcggtgc gcgatacgcg gtcaaggatg
   107161 ccgtgtccgc ctccgagtgc gcggcggaga acatcgtgct caaggagatc gcccccttcg
   107221 ccatagagga cactggcggc ctgttcgtct cgctgccgga ggacgatcct gatttcgttg
   107281 acctgttcac cacttcttgc cgttcggcag gcgttcccac tgaggagctc acgtccaagg
   107341 aggcaatcgc ttgcgaaccg gggttggatc ctaaggtggt cagctgcttc aaggtcccgg
   107401 acggttccgt cgatccattt tcgctggtcc aggccaacat ggatgacgct cgttccgctg
   107461 gcgctaccgt tctcaaccat tgcgccgtct ccggaatgac ggtccaggat gggagggtgg
   107521 tgaaggtcga ggtccgggac cgacgtggcg gtctcccatc gtcgatcgtt ccggagttgg
   107581 tggtcaacgc cgccggggcc tgggtagccg acgtcgctag catggccggc tgccatgttc
   107641 ccatgggact ggaccagggc agcatgctgg tcctggacgg tcgacagtgt agacacgtca
   107701 tgaaccggct gagacagcct tcaaatggcg atatcgccgt tccgaaccac acgtccacga
   107761 ttttgggcac cacctctcgg ctcgcgcgat caccgaacga tgtggcggtg tccaaggagg
   107821 acgtcgagct tctgataaag gaggcctcgg ccatgctgcc gtccctccgc gaatgccggg
   107881 cgatacgaac gtatggcggg gtacgaccgt tattgggcgg aggtggtagg gaggccagtc
   107941 gttcctttgc cataatgagc gatgacaagg tggacaacct gttgagcgtg gccggcggaa
   108001 agctcaccac ctataggctg atggccgaga aggtctccga tcgggtgtgc gaaattctgg
   108061 ggaacggcgc caattgccgt acgcacctgg agaagctcgg gcccgccccg gatccgaagg
   108121 gaggttcgat ctcttcggcc aggctaaggc gcaagtacgg acgggcggcc acttcgatag
   108181 ataccgccga cactcgggtg ctgtgctcct gcgaacaggt catgcgttcc gaagtgacga
   108241 tggtcctgag caagggggac gctctgacac tggccgacgt gatgcgcagg acccgggcgg
   108301 gaatgggtta ctgccagggg ttcgactgct cactttccgt actggaggtc atgatagaac
   108361 ggaaccaggt agatcctgtc ccctccttga aggaattcct tgaggaaagg gaacgtggcc
   108421 tgacgcaagc gaccggcgac cagctgcgac aggagattct gcgccgacac gtcctcagag
   108481 gcgtctacgg gctggagggg aaggaatgaa ccgcgttctc gtggtgggca aaggggcggc
   108541 cggaacgttc tcctcctggc tcttggcgaa caagggttgg gaggtcatcc tggtgggccg
   108601 ggggaccccg agcaccgcca tgtccactgg ctgcctgagg tcccaaccga acgtttgccg
   108661 ttcggagatc atggagtttc tgaacaacga aatgatgccc tggacctacg gatctaggga
   108721 aggcatgagc aagataggaa cgtcataccg atgctggatg tccccgcccc attccacctg
   108781 gaaggaaggt gaggcgccaa agagcgtcgc ggtggtcggt ctggagggac atccatctct
   108841 gcaggcgcgc gtagcctcgg ccacgctgaa cgcccggggc atcagggcgg agtcgctcat
   108901 attgccgagc tcggtcccct cggatgttcc cctggccgcc tctttattca gtgacgaatc
   108961 ctgggagacg ttggccgacg aattgcaaag acaatcggcc gaagcgatac tgctcccggc
   109021 catggtcgct ctggaagact atcaccagct ggacatactg gagcttcgca gtggaaggag
   109081 agtgttggag gcgatcactc ccctgagcgc gccaggtcag aggctggggg atatcatgcg
   109141 ttcgaaggcc gcagggtcag gggtaaccat ctgggacggt aggaaagtaa ccgctctcga
   109201 tgtacgggac ggcgaggtgc gcggagcgac ggtcgccgga ggtcaagagg tccgcgatat
   109261 cttgatcgat gcggtcatta tcgccaccgg gggccccctg gtcgatgggc tggctctcaa
   109321 ggaacggaat atcagcgatc cctttggtat gttccaggtc gttcgatcca acgacgggct
   109381 cagaggcggt tacgatagct cgaacggcat gctgatcgcc agcgatggtc acccaatgaa
   109441 caacgtcgcc ggcgccgggg actgcctttc ttcggaacgc agggaatacg gctccgggtt
   109501 gaccgaggcc ctggagggcg cgtatcttgc cgtccaggca ctggagggat catgaacgaa
   109561 ggccggtgcg tcaagtgcgg cagctgcctg cgggtatgcc cggttctcaa cgatctctca
   109621 ggttcgccat tcccaggacc acgaaccgtg ggagtggacg ccccccggtt cttggagaga
   109681 gaaagcgtcg gccacaacgc tctgcgctgc accatgtgcc atgcctgcga gtgggcctgc
   109741 ccctccggga tcaccctcac ccgctccatg ttaaagctca ggtcggggat gtccggtgaa
   109801 cgtttgcccg gtcatcgccg gatgctcgag aacatatcct cgttcgggcg atcggtcaat
   109861 acggagttca gtggctggat agagaaaggg aatcgtaccc tgtacttccc aggatgcatc
   109921 ggtctcggtc gttccgcgga cctcacgaga acggtgtctt ccctcctaac ttcgctaggg
   109981 atagagcacg atatctcgag ccaggtcctg tgctgcggtt ctccacttct gaagatcggg
   110041 gccacagagg tggccgagga cctccgccgc cggaacacag aggcgctctc gcggtacgac
   110101 cgagtgatca cctcctgccc cggctgcacg tatcagctcc gggagttcta cgggatcgag
   110161 gccgagcatg taatagaggt cctgaagggc ttggacctgc gttccaagct ggaaggccgc
   110221 tgggcgctac agattccttg tcacctgagg cggggcctca gtccctgggc cgccgaggac
   110281 ctgataatta ttctggagaa tgccggtgtg gacatcgtca ggatgcccca ggaggacagc
   110341 tgctgcggcg gcgggggagg catgctatcc ggctttccgg aaacgtccgg ctccatcgcc
   110401 cgccacaagg tcgatatgta ccgccgggcc gaggtggacg gcgtgataac tgcctgcccc
   110461 ttctgctccc tgaacctggg aagggaaggc ctcaaggtcc tggacatcac cgaggctatt
   110521 acgctgaaca aatagggaac catcaaatac accatgcacg atagaacgcg ccagatgaac
   110581 aaggcgctct gtttttcctg tctgcatcgc gagaaccgcc ccgagctggg gttgagcgat
   110641 cagctggtgt actgccgaaa gaaggagatg gtggtccggc ccaagatgga atgcacgctg
   110701 tattccaagg ccaccgcccg tgccgttcag gagctgaatc gcgctctgta cggggtcatg
   110761 gaagaagccg aggattgatc acttccactc cagtactgga gctggcgctt cctcgcctcc
   110821 cggggttatc tcgaacggta tccaccggcc gggtaccgac atgccgcgca tgtgccgcac
   110881 cctcaacacg cgattgagat cgttatcgaa gcgcagttcg atgaccccat ccgccaacgc
   110941 caccaggtga ttgagggcct tctcctcgtg caccccgtcg aacacggaca cgatggccgt
   111001 cccgaactcg ctccgtatgc gggaggtgct gatctggaag aacttgagca ccacgctggc
   111061 ctggttgtac aggaatagcg tggaaagggt atgcatgaat accctcagag gacgcttctc
   111121 ctcagcgaat atgttggcca cgttgaacat tattccttcc aggtcatgaa tgcggcgcac
   111181 cttggtacgg tccccggcct cgcgatcgtc cccgttaccg agcaggctgg agtgataatc
   111241 gatcacgtat agcccttttc ccaggaggtc caacgagatg ccgaagcgct ccatggatgt
   111301 aaacaggtcc ctaggcagca ggtccatggt cacgaagacc accggttcgc cctggtccag
   111361 gtattccttg accatgctca tctggaactc caacaaccct acgcccggtg ttcccaaaat
   111421 gagcaccgag cacatctgcg gaaaattggt cctgaacatt caaagcacct cacaccagcg
   111481 gggtcaggga cacgcaccct ccctggggtc tttcctctac cgtcaatgcg aagcactcgg
   111541 tgaacggttt actgccgtag agcaccaccg tcccgcctat cctctccacc ttcaagtgca
   111601 ccgtggccag atcggccagc cttgccgtgg atcgggatgt cggggaggtc agtcccacga
   111661 acgaccctcc attgcgcttg accgcggcga gatgatcgat cagtccctcc atgacctctc
   111721 cgccgtaaat cgattccagg gaatcgaacc ccatcagcga gaggaacggt tgtgagctgc
   111781 cattcagagc gtaaacgatg ttcttccact tcaggtcgtc cgataccctg gtcccttcga
   111841 cggccatgac gtaacgtccg cttccctggt ccatctggga ggccggttcc acgacccgaa
   111901 ccgtcttctc catctctccg tccgtcaaaa cgttctgcag catccccctg gctcccgccc
   111961 cgctctcctt tcgcaaaggc acccacagca ccccgcgccc ggccttggca aagctggaga
   112021 ccaacgacct ctccaatatc ccactgacca acgggggaag cccgccgccc agctcgatga
   112081 gcgtcaccgc tcccgggaag aggcccccag tcatttcgtc cagatcggtt atcccgaacg
   112141 agagatggcc cgcagggtcc tccggtctgg cgaactcatt gctcatcccg ctgccccggt
   112201 cccacttggc tccgaagcag cggaacttgc cgcccttcaa actgaaaaga tagaggggct
   112261 gctgaacctc cacccctcgc agcttcataa ggtccatctc tcgcaccaat cgccgctcgt
   112321 gctccatccg cgtgcactcc acgaccccgt ctcccaggta atcgagcatg tggtcgttgt
   112381 tctccaggac gaagagcagg ttcgccccct ggccttccac caggtcgcgt tgcagggcga
   112441 tcatcagttc ccggcactgt agttcgtatc ggtctgccag agcgtcgatg ctgtcgatga
   112501 tgaccagcac ccgttccccg gccttctcca ccaggtcata caggttctcc aggtcgggca
   112561 tggtccggcc gatggagacg gtcatctcct tccgggacac caacagatcg ccggagccca
   112621 cgcccttcaa tcgtccgaag ccggaacggc gacgggtact ggtctcctcc ctggttatca
   112681 aacggtcggc aagccaggga aactgcctta gcagggacga atcggatacc ctggtcgaaa
   112741 gatagtgtgc cctctgccgg tccttgaact cctccgccac ctgcagaacg aaggtggtct
   112801 tcccggtccc ggcgttcccc cgcacgatga gggaatgccc tcccgggttc tcgaggaatc
   112861 tcgtgatctc attgggcaac gcggaattgg aggggtcggg catctgctga accttgtccg
   112921 cttgacccct ctcgattttt aaacaacttt cctccccatt atcatttatc gccaatcaga
   112981 tggtgcgaaa aagattaata aacggccaca gggatggcta tgccctgagg atcctttgat
   113041 gaaagctgtc attctggccg ccggggaggg gaccaggctc cgtccgttca ccgtatccag
   113101 gcccaaggtc atgattccca tcggcaaccg acctatcctg gaatatgtcg ttcgagcctt
   113161 ggcggcgaac ggcataaccg agatcatcct ggtcgtgggc tacatgaagg agcgcataat
   113221 gtccttcttc gggaacggct cacgcttcgg ggtcaagata tcctattcca tccaagagaa
   113281 acagctgggt accgcccacg ccactctggc ggtccgaagc cagatcaagg acgacttcat
   113341 attggtggcc ggggacaaca tcatcgacgc ccaggtcatc gccgacctcc tgaaccacaa
   113401 gggtggcctg gccatgctgg tgaccgattc cgagatcccc tccaagtatg gggtcgtcca
   113461 gatcgagtcc ggtcaggtgg tggacatcat cgagaagccc gacaagaagg tgggcaacat
   113521 catcaacacc ggcatctacc gattaccgcc caccatattc gatcacctgg agaaggggat
   113581 catggccgga aagtccggga tcactcacgt tctgcacagc tgcatgcctc gtctgaaggt
   113641 ggacgcggtc cgttccaccg gtcgttggat ggacgccgtc tacccatggg acctcatccg
   113701 tttgaacgag tatgccttca gcctatcggg tcaggagaca tcgggtacca tcgagtccgg
   113761 ggttaccatg cgcgggccgg tgtacgtggg ggccggcacc aggatccgag ctggctgcta
   113821 catcgaggga ccggtgtcca tcggcgaggg ttgcgagata ggtccgtacg tgacgatatt
   113881 tccgaccacc agcataggca acggggtgca catcgctcct tacacctaca tcaacaattc
   113941 catgatcatg aacaacgtct ccataggttc ccatgcccac atatcccggg cggtgatcga
   114001 cgacggatgc cggataatga ccggcttctc cgcgccatct ggcctggccc aggtcagggt
   114061 ggaggacgat ttcttcaagg tggagaaggc cggcagcatg gtcggggagt tcactcagat
   114121 aggtcctcag gtggtgctgt ccgccggaac catcatcggg gccaactcac gagttggcga
   114181 cggcgccaag gtcagcggga cgctggagaa caggagctta gtggtctgat gtgcggcatc
   114241 gttggatact cgggccaccg ccgggcctcg gaagtgctga tggagggtct gaaacgattg
   114301 gagtaccggg ggtacgattc cgccggtgtc gccatagttg aggatgggcg cctggtgcta
   114361 ttgaagaagc agggggagct ggaggtcctg cagaaggccc ttcccaagtt cgaaggtcgc
   114421 acggggatag gccataccag atgggccacc tgcggtcggc cgtccgatag gaacgctcac
   114481 cctttcgtgt cctgcgatgg aaagctggcc atcgttcaca acgggatcat cgagaactac
   114541 accgctctgc gggaacggct cgaatcggaa ggccaccact tcacctccga gacggacacc
   114601 gaggtggtcg tccatctcat ggagacccat tacaccggcg atctgcgcca ggcacttgcg
   114661 gacaccaccc gggagattca ggggacatat gccatcgcgg cggtcctgga gggcagccta
   114721 gaggtcgccg ccgcccgtaa ggagaaccct ctggtggtcg gactgggggt caaggagaac
   114781 ttcctggcct ctgatgtcac ggcgctactc agttacacca accaggtact gtacatcagg
   114841 gacggggaga cggtctctct aactcctaag ggggtaacgg tcttcgatca ggacggagcg
   114901 atagtgaaaa gggagacctc cgtggtgacc tggtccgccg aggacgctca gaagggcggc
   114961 ttcgagcact tcatgctcaa ggagatattc gaagggccga acgccattca caacactctg
   115021 ctgggggcat tggacctcat cgagaatggg gatgtgatac ccaggatgga ctttagttcc
   115081 gtgaagctag tggcctgcgg ctcctcgttc cacgccgcca tggtcggcaa gtacgccatg
   115141 gaggagttcg ccgggatacc caccacgctg gagctggcgt ccgaataccg ttattcacca
   115201 gggaccaggg aggcaccttt ggtcatactc atcacgcaga gcggggagac cgcggacacg
   115261 ctggccgcgg caagggaggc caggcgccgg gggtgccgca ctttggcggt cacgaacgtg
   115321 gtcggttcca ccataaccag ggaggtcgac gaggtcctct acaccaaggc cggcccggag
   115381 atcggcgtgg ccgcgaccaa gacgttcctc acccagcttc tggccatgta catgttagcc
   115441 atacgaatag gctacgccaa tggcacgttg agccacgacg ccatgcgtag cgcattatcc
   115501 tccttgcgcc aatcatccaa catggtgcag tcggtgctga accacatgca cgagatcgag
   115561 gaagcgagca agatgatcga cgaatccgag cactgcttct tcatcggacg caacatcaac
   115621 tacccgacga tgttggaggg cgccctgaaa ctgaaggaga tatcgtacat ccatgccgag
   115681 ggattcgccg ccggtgagct gaagcatggc ccactggcgc tattggattc taagaccccc
   115741 gtgatagccg tagccatcaa aggcgaccac acctacgaga agatgttggc gaacatatcg
   115801 gaggtggccg cgcgggacag tccggtgctc ggtgtgggtc tggagggcga taccgacctg
   115861 tccaggttat gcgagcgcat gatatacgtc ccgccggtaa aaccggtctt ctctcccata
   115921 ccggtgacgg tcgcgctcca ggcgctgtcg tactacgtgg ccaaacgtcg cggctgctcc
   115981 atagacaagc ccaagaacct agccaagagc gtcaccgtgg agtgatcaca ccagcttctc
   116041 tgggcaggac tctcggcggg agcagctggc gcacttgccc ggtcggttgt ggttgcggtg
   116101 cacctctccg ctgcgcatca gcttgcgcat ctcatccacc ttttctaaaa ggatcttctc
   116161 cagctcggcg tcgaactcga tctcatgttc ctcgctccca tatagcagaa gaccgtacgg
   116221 agggcgcttg cccgacgatt ccgcgatgag caggcaatag gtcgccacct gcaatatatg
   116281 cgagaacaac ggtcctttcg gggttcgtcc ggtcttgagg tctcccggga tcaattgacc
   116341 gtcgatctcc agcacgaagt ccggtcggcc gctgagcccg tacctctccg agagatacaa
   116401 ctgcgaatcg tccgttccaa cgtacttgat ctccccctcc aggccttcgg cgttcatacg
   116461 ctccccgacc ttctgggagg cggagagcga caagtaaagg gcgagcgagg cggcaatcag
   116521 ccagaccagc gccaaggcct ccagtatcat ggagaccatg gggtcggcct ggatgaggtt
   116581 gccgatgttc atagccacca ccatgaggac cagtccaacc atcgccacta tctgcaatct
   116641 tcgaacttgg atgatggccc tccctcgcag ggctgaaaga tagagcatgg cgatcaccgc
   116701 caggaaccag atgatgctca gcaggggcaa tatccatcca atgttcacac tgccggcggc
   116761 ccgcatcaag gagatgccgg tgacggccag cacggtcgcc accagcgaga agaggaagac
   116821 catcctttcc cagtcccagg ccttctgttc tatgttccgg attcggcgat attcatcggc
   116881 cttgtcacgg tgtgcggcat cccccctctc ctgctcgggg gtgctggact gggacttccg
   116941 tcccaaccac cagctgagcg ggcagtaccc ataccgctct aaatcgctgg cggagatgac
   117001 ctcggtccgg tccatggact aaaataatga tgatagatat ttaaggtgtt cagcttccgt
   117061 tcactctagg taacggcagt tcagcccggt cagggaagcg tccgttatat agatgccgtc
   117121 ctccatggtt atctcgtcca cgaaaccgaa ccagtagacg accaggcctt gaccgaacag
   117181 ctccacgtaa ggcgagagct gcttcttggt gttcttgttg acctccacga aatcgccgaa
   117241 ggaggccttg gactctatcc agttgatctt ccaaccgttg accatgatgg gtttgtccag
   117301 caaggcgtca ggggtcttgg tgaaacttcc gcgcagatcg ttctccgtgc ggtaggttat
   117361 gccctggctg tccagccagt cctgaaggtt cttctcgccc catttcccgc gcaatttctg
   117421 cttcaggtcc ccctcgggag agttgatgat gtcagcggcg gttatctcct cgatctggcg
   117481 gcgcagctcc ttgtccgtta tggcctccgg gttgcgtacc aaggcccagt actgcttgtt
   117541 ggaccgtcca gactcattga aaaggaccag gccggtgagc acgggaggaa attcgtagcg
   117601 gcgcgctatc tccaacaagg tctccccgct tcgccaggac ctgagcaacc ttggcgcgtc
   117661 ccgcttcacc ttataatgcc tcttcatgga ctccctctgg gtcctctggg agtatattac
   117721 ggtcagaagc tcgcggtcca ggttcagttc cttggagaga acatcgatat cagagggttc
   117781 cttcaatcgg tcgtacaggt atttgaaatc ctcattcttc atccatttca accttgacgc
   117841 ctttcgtagt cgaagtatga tatataattc ttgtgagttg gcacggacca aaggcacagg
   117901 accattggcg gtcagataga ttgaaatttc cgaatgccat gtatgaaatc cagtgggatg
   117961 gatccctttg gaggattaag atggacctga acaatttcct ggcatccgag aacggcccgc
   118021 cctggcttcc agccagtgtc gccgaggccc gcaagctggt ctacatcgga cagctcttcg
   118081 ccctgatatt cgcattgata gccctggtga taggcgtgct gaacatcata tccggcacat
   118141 tatacacagg ggcttactcc ttggtagccg ccgccctggg catggtgctc ctgttcatgc
   118201 tgaagaaaca ggtcttcgcc aacctcgatc agggaaggtt caagcaggcc agcaactccc
   118261 ttctcatctg gacggtcgtg ggcttcttcg tctgggtcat tcccggtctc atattgctca
   118321 tcgggttcct gaagctacag ggcgtcttcc agctgcagta ccaggactac caggcccagc
   118381 agtatcaggt ggcgcaggag cctcaggccc agcaggcacc gcccgcgcag ccggctccgg
   118441 ctcagcccgc ccccgtcgct cctgagcagc ccgctcccgc tccggcggag cacaaggaaa
   118501 agaaggttga gatggccaag tgccgcaagt gcggtgtcaa ctatccggcc ttcatgcaca
   118561 actgcccgaa ctgcaacgag ccccggcact aggcctggaa aacaacttcc cctttctttt
   118621 ctatctttac tatccggtgg tagggtatct gcccttcccc taccgtgaag aaagacctgt
   118681 ccaggtcggt gatgctctcg ccctttactg atgccaggtc gtccggtccg ccgcggtgga
   118741 tgtaagtgat tacgacatcg tgcagaccgc cgtctcccca tcgcaacttg ctgaggacct
   118801 gccggggata ggtcatgatc gttcatcgga aggaacggtc aaaaggtttt tgcattccca
   118861 aggctgaatc ggttccatga gccggaagtc ggtcgaaggt cagttggtgg acgtggtgaa
   118921 cggaaagatc gtccccagcc gggtgatcat ggaggacggc aagttctcgg agatcgtcgc
   118981 tcttcccgac gcacccaaga gatacttgct gcccggtctt atcgattccc acatccatat
   119041 cgaatcatcc cagttgtgtc cttcgcgctt cgccgaggcg gcggtgccgc acggcacgac
   119101 ggccgtggta tccgatccgc atgagatagc caacgtactg gggatgaatg gcatcgaact
   119161 cctgttggag gacgcggcga acgtgccgtt gcgaacatac cttaccgccc cctcctgcgt
   119221 tcctgccacc cagtacgaga ggtccggggc gaccataggg gtggcggaga tcgaggccat
   119281 gctcaaggac cctcgtttcg tcggtctcgg cgaggtcatg gacgtgcaag gggtgctgaa
   119341 gtacgacccg ctcatcatcg ccaagatcaa ggcggccaaa tccttctgga aagggatcga
   119401 cgggcactgc cccggtctgg tcggaaaaga cctggtgaag tacatcaacg ccgggatgcg
   119461 cacggaccac gagagcctta ccgccgacga ggcggaagag aagtacttcc tggggatgtg
   119521 gatacaggtg cgggagggca gcgcctcccg ggaccttctc tccctaatgc ccttcgccaa
   119581 gacgcacgag tgcatgctgg tctccgacga tctcagggcc agggacctgg tgaacggtca
   119641 tctggacgtt ctgctgagaa aggcggtcgc cctaggcatg ccgcccatgc acgccatccg
   119701 ggcggtgacg gcctggccgg catggcatta caacctgccc gggggaagcg tggccgtcgg
   119761 ccggacggcc gatctggtgg tcgtggacga cctgcgcaat ttcaacgtcc tgcaggtata
   119821 catcgccggg aggctggtgg ccgaggacgg cgtcccgcta ttcctagccg agccaaggac
   119881 caacggtctt ggtattatgc ccagggacct ggtcggcgag gacatgttgc tgccggcgga
   119941 agggcagaag gtgtccgtca gggtgatcga ggccttcccg gaccgcatcg agagcggttc
   120001 tctggtcacc gagctgccgg taaggggcgg gcaggtcaga gcgcttccgg agcaggacgt
   120061 gctccatatg gctctggtca accgctacgt ggaggagagg ccggtactgg gattcgtaaa
   120121 aggtttcggt ctgaggcggg gggccatggc tacgagcgtc gcacacgatt cccatcacat
   120181 cctggccgtg ggcgcgtcga tcgatgatat ggcgagggcg atcaacgccg tctcccgctc
   120241 cgggggcttc gcggtatgcg atggaagcga catatccacg ttgccattgg atctggccgg
   120301 ccttatgagc acctcccccg cccgggtcgt ggctcagaag gaaagcgagc tggtagatat
   120361 gctggcggga atgggttgcc gcatgccggc tccgttcatg accctctcgt tccaatcgct
   120421 tctcgtggtt cccgaactga agatgagcga ccgcgggctc ttcgacaccc ggcggatggt
   120481 cgtggttccg cccttacttt aggaggcaaa cattattttc ccgcattacg gtcgtggtgc
   120541 ccaacggggt ggaccggatg gataaggtgg agagcttcaa gtgccgtatt ctgacctggg
   120601 acgagatcgc gcggtggaca gaggccgtgg ccaacgacat agctgacaat ggtttccgcc
   120661 cgaccgtggt catcggcctc acccgcggcg gctgggttcc tgcccgggtg atatgcgatc
   120721 atctgcaagt taagcgcctc tacgcggtga agaccgaaca ttggggggtg accgccaaca
   120781 cggacgggaa agcgcttctg acgcaggagc tcaacgccag catagtgggc gagtccgttc
   120841 tgatcgtgga cgacatcacg gacaccgggg agagcttgat gctggccgag aagcacctaa
   120901 aggccatggg gccgaaagag gtgcgcaccg cgaccttatt gcacatcacc cattccaaga
   120961 agcaaccgga ctttttcgag gtcgaggtcc cgaaggagga ctggacctgg ttcatattcc
   121021 cctggaacct gcacgaggac ctgcgcacga tcctaccaaa gacgctctac cagcctcaga
   121081 ccgtcctggg catccagaag ggcttcaagg agcagttcca gatagatgtg cccgaggacc
   121141 tcattcgccg cacgctgaaa catctgacag tatccggcaa ggtcaagaag aaaggggcca
   121201 aatggcagag gaccgacggt gacgaggctc tgccgcgaaa gtgatcagat ctctatgtac
   121261 acatcatccc cttccaggga gacgatgtag acccgcaggt ccttggctcc ggaatgagtg
   121321 accttctttc cgtcgtggac atcgaacgtc gcgccatgcg ccgggcagac caccgctcca
   121381 tcgcgaaccg ttccgtaggc aagatcgaac ccggcgtgcg agcacttacc gtccattccg
   121441 aacaattgcc cctggtaacg cccgaccacg aacttccgtc cgtcgaccat caccgatctg
   121501 agccgtccct ctttgatgtc cgcgtccttg ccgaccagaa ccttcatgtc agccgaatcc
   121561 cagcatcagg catataatga ctgccaagga aatcgcacaa ttaatgagcg accagtgcga
   121621 tatccgttac gagctgcatg ttggagaaat tgaaggagag cctggaacgg agcgatatcg
   121681 tccgcttcgg ggagtaccag tatttcgtgc accccatcac tgacggcatt ccggccatgg
   121741 acccccaggt gctggacgag gtgcttgacc gcatatacga cctcctggac ctgaacgtcg
   121801 attatctggt gggggcggag gccatggcca taccgctcat cgtgccgtta tcgttgatga
   121861 ccggcattcc ctacaacgtg gtcaggaaga gaaggtatgg tctgccgggc gaggtgagcg
   121921 ttcgccagac cacaggttat tcggagaagg agctttacat caacggattg aagaaagggg
   121981 accgggtaat agtgctggat gacgtggtca gcacaggcgg gacgctccgg gcgatcgtca
   122041 aggcgctcaa gacgatgggt gtcgacgtca gggacatcat cgtggtggtc aagaagacgg
   122101 acaagctgga agaactggaa aaggacatcg gccagaaggt ccgcaccctg gtgagcgtgg
   122161 aagttaagga cggcaaggtc cacgtcattt gaccaggcgc ttcttcatca gatataccga
   122221 cccgaggaag cacaccgccg ttaggacgat gatgtaagcg gctccgatcg caacttccgt
   122281 cgtaagcatg ttgtacgaga ggtccctggt catgttggat atgtgcgtca gcggtaacgt
   122341 catcgccagc tgctggcccc attccggcag cacgctcaaa ggaaagaacg tcccgctgaa
   122401 aaggaacatc ggcgtgatga acaggaagaa cgggtagttg aaggagtcca tgttcggcac
   122461 cagggcggtg aaaagcatcg ctaacgaagc gaacatcagt cctccgacga aggcgatcaa
   122521 cggtatcaac agcaatcccg gcagttctgc gtaacccagt accgctatga cgcccaggac
   122581 tatggtggcg ttcacgaagc tcttggtcgc cccccagagt atctccccgg tgatgatgtc
   122641 ctccagtgat aacggtgtcg cgagtatggc gtcgaacgtc ttctgatagt acattcgaac
   122701 gaaggaggag taggtgcatt caaagaacgc gccgtacatg atgctgatag caacgagacc
   122761 gggagccagg aactttatgt attccacgct ctccccgccg tacactatgt cggcttgaat
   122821 gagcgctccg aagcccaggc ccatggccac caggtatagt atcggctcca ggaacggcgg
   122881 gaggaagttg gtcttccagg tggtcaggaa cacatcacga ttgcgtttcc agagggcgag
   122941 ggagcgccag gagatgttgg atatgaggct cattccacca gcgccctccc ggtggagcgg
   123001 aggaacacat cctccagcgt ggcgttcctg atgaggtagt agctcatggc gaagcgttcc
   123061 ttgatctcgg ctgccgtctt ctgcccttcc ttggtgaata tcagcaggcg gtcgatggtg
   123121 cgttcgtact gccatccctg gcctttcacg tacgcttcca tttcgtccgt agggacatct
   123181 atctccatca cgtccgttcc gatgacggaa tcgatgaggt cccgcggttt tccttccagg
   123241 attatcttgc catggtccat gatgaccagg cggtcgcaca accgctccgc ctcatccatg
   123301 taatgagtgg taaggatgac cgtgaccttc ttgcgcttca gctcgcgcac cttctcccag
   123361 atgaggtggc gggcctgagg gtccagtccc gtcgtcggct cgtccagtat tagcagccga
   123421 gggtcgttca tcatggcccg ggcgatgatc aggcggcgct tcattccccc ggagatctcc
   123481 tggatgcgct cgtcccgctt ctcgctcagc tgcatgaact ccaatagccg gtcagcgcgt
   123541 tcctcgagca catcctttgg cagaccaaaa tagcgtccgt agacggtcag gttccgacgc
   123601 accgtgaaat cggggtccag gttgttctcc tgcggggcta cgccgatgac ggccttgacg
   123661 tccctggaac ggtcgttcac gtccatcccc agcacctcca gcttcccgga ggttataggg
   123721 ctggcgcaat gcatcatgcg catcgtagtg ctctttccag ctccgttagg cccgaggaac
   123781 ccgaagcact cgccctcctc gatctgaaaa tcgatggcgt ccactgctct cagttcgtcg
   123841 aacaccttgg tgagcttctc cgcgcgcaca gctggcatga acggcccgct atcgatttgc
   123901 atatattaag caggaatgcc ggttagcctg actgcagtca ctgagctatt gaccagtggt
   123961 acggctggtc aagcgtgttc ggcgcggacc ttcttctatt gctatatttc accctgttcg
   124021 ggatgggtct gggggcgttg tccggactcg ctccgggaat acacgtgaac accttggccg
   124081 tgctgctgat aatgagcgtt ccagcgcttt cgcctttcct ggaggatata tgcggttcgg
   124141 tcggctgctc gctcccgccg gccctgttgc tgtcatgtac catattttcc gcggcgatat
   124201 gccattcctt cctggattac ataccgtcgc tgatcatggg cgtaccagat gaaacggaat
   124261 gcatgtccgt cctgccgtcc cataaactcc tcctcgaagg gaagggaatg aacgccttgc
   124321 aggcggcggc ccagggcagc ctggtcggcg ccatggccgg aatgatagtc ctattgccgt
   124381 tgccgttcgt tcaccttcag gccacgagcg tcctcaatgc cgtaactccg gccattcctt
   124441 ggttgctact tgccgttccg ttcctcctgt tctgggcgga gagcggaaaa gcggatccca
   124501 aggcggagct ggacatgagg ggcgggggtt ccacgccggc cgagatgata tcgctcaaac
   124561 ggcacatacc ggtgcacggg gactcggcca gggtcatcgg ttccgtcaat cgtcatcatg
   124621 gaagatggta cgtccggacg ccattgcaga ccttccgcat acgcgggcga tggatggagg
   124681 ccggggacca aacgctgatc gggaaatgga tagtccgcaa ggaccgcctt ccgatatcgg
   124741 gctggtccgt tctgcttttc ctttgctcag ggatcctcgg cgtcatggcc atggacgggc
   124801 tggtccccgg cgaggacatc tggaaaggaa tggagggcaa catgctgatg cccctcttca
   124861 ccggtctctt cgggctccct ttgctgatcg gttcgtctcg cggacgcatg cccgagcagg
   124921 atggagaggc ggacgtatcg ccatccgtga ccggggctct gaaaggctcg ttcatgggcg
   124981 gtctggtcgg ctggcttcca ggagtgacgg ccacggccgg agcggtgctt tcgaccatgc
   125041 ttcctcgttc ccgcggaggc ccagaggagt tcatatcgac cgtgtcggcc gttggaacgg
   125101 gagcggcggt gctcgggttg ggaacattat tgctcatcgg caaggggagg agcggaacgt
   125161 tgctagcgat gcaggaggcc atgccctctc tgtccgtaac ggaaatgcct tccctgctgt
   125221 tgtgcatact gttcacatca ctggtatcat acgttctgac catgcgcctc ggccgtaaac
   125281 ttctggtgaa ggcccaaggg cgggacctaa cgaaattgaa ccagggggcg ctcatcggaa
   125341 tgatcgtcct ttctttcgta ctggccggcc ccggcggtct gcttctattg acgctgtcga
   125401 cgattctcgg catggtaccc gggaagatcg gcatcagccg agtgcacctg accggctgcc
   125461 tgctgctacc aatactcctc tactacttcg ccccgttcct gcgatagaaa tctcgtagac
   125521 ggtcctggcc cagctcgaac ggcgacagca gctcgcccgc cgtgcggaac agaagctcct
   125581 cgtaccgccc gatgtcgtac tcctcgtccc cttccaggaa ctgggccacc ttgacctcct
   125641 tgcccttgat catgatgaac tccacggcct cgccgggcgg cgtgcggaag ccctggtcct
   125701 ccagctgggc gagcgcccgg aactggtcgt tcttctgccg gtagtcgttc agctccctgg
   125761 ttattcgttt ggatagcacc agcttctcca gcggcacctc catgttcctc aggttccgta
   125821 tgaacgaatc caggacgtcc aacgcttccg gtatgcgatg acggaagccc tcagcgtcct
   125881 cgccaagcac caatcgatct agcatgccct gctgcagctc cctggctagc gtacaggtgt
   125941 cccttctgcg cagagctatg ccgcgaacct tcagctcccc gtcctgaaaa gctccatagt
   126001 aacggttcaa ggcgcccgcc ccgttggtca ggttcggcag gaacacgatc cacttgtact
   126061 ccccgtccca gaccagcggt atgcccatgc gctgccctat ctcccggcag taggcctcga
   126121 tgtctccgtt cccggaaagc cacaaggagt ccacgatgcc atgcagcacg cggaagccgc
   126181 ggttctcggc cacctccgcc gatttgagca gtatctcccg gccatgagcg gtgatcgatt
   126241 cgtggcactc gatccgtccg aagcgggcgt ttcgatagcc agtatagccg aagcaggtca
   126301 ccagcaccca cttgagcacc ttggcctgct gatcatagat ggcgctccgt cgcccgccct
   126361 ccttcttcag gcgcttgagc gatattcgtc ggcgcacgat cggctccagg acgcgaccta
   126421 gcaatccctt gcgcttggag caggtccagt aacctagtcc tggcacgggt tccccgctgt
   126481 cctggcagca atcgcagttg agcgtctccg gagatatgtt gtggcggacc atgatgctcg
   126541 ggtagagcga ggtgaagtcc acctcctgga tgtgttcatg aagccccacc ttcggttcgt
   126601 atatgagtcc tccgcgatcg caggccacca gctcagcggc ggtcttgaaa tcctccggca
   126661 ggttcttctt ccacatcacc agcgagccca tcttgctggc ctcgttcacc tgcatggcgc
   126721 tgatggcgct tcccggggac atgcgggcca tgtcctgcgg tgatatgcgc gacaggcgac
   126781 taaggtcgat cagtccggcc atcttcccct cttgaaagat gaacgatgat cctttgtcca
   126841 gatgaattcg cccgcgcagc ttgtaagccg gcggtttgta aagaatgcgt ccataagtga
   126901 agtagctctt cgccttcccg cggcgctttc ctccttcccg tccgagctcc agctccatct
   126961 cgttgcgctc ggcgcacttc tccaggaacg gaagatgaaa gctatcgcct ccgtcagtta
   127021 ccagcacgtc cgggtctttt tcgcgcaaag cctgctgcaa tagttccaga atgtccgctt
   127081 ccttgccctc catgacgata tcgtcgagag tggcccgctt caggtggtcc tccatggtcg
   127141 gcattccccg gcggacggag gtttccaacg taagctcgca ggtgcgcagc tccggcatcg
   127201 gatagtccaa tcggaacggg gtgtccaggt tcttccagcg atccacgtcc ataagtccca
   127261 tcgggaacac cttgcggtgc aggaagtagc gggtgtccat tcgcgtatcg acgttgaaga
   127321 gcgtgtggtc gcggtggcat ccccacttgt ctatcgtctt cgccaagggc atcaggttgc
   127381 ggtatccgcg tggggaaacc ttcagcacgt cctccaaagg tccggtcagc caggtgcggt
   127441 gcttctccca gcgatgctcc acgcccgcct ccttaagacc gagcagcagg tcctgtctac
   127501 gctccgagga tggtttcacg taaaagcacg ggcgatactc tctgtcggtt attcgctcca
   127561 ttcccgtgga cgtcttgatc caggtcacca tctcgttgtt gacctcgtcc gcgtagcagt
   127621 ccaggatcca tccgcgcatt cgatcaggcc ttcttgcgca gacgttccag ctccttctcc
   127681 tgctccagga gtatggatag cagcgctcct tccaaaggat cgaggaaggc ggcaatggaa
   127741 caagcggagg cgtgcagccg gaccttatcg gaaaggcggt cgaacgccgc gcggtcctcc
   127801 tgcgaaaggg cgcgccggaa atcgctccag ctctggaaga gggtttccga ggccatgcgg
   127861 tacgttggaa cggtccttcc catcagaacc gcctccggta ctcgtccaag gtggtctggt
   127921 tcggcggtac cggccggtac atgatctcct tctcttccct aggtaatgat atgcgtacgt
   127981 agccggagcg gtgctccacg ctgaccaccc tgtcgacctt ctcatagaag agggagcgca
   128041 gccccttgcg gtacatcagc ttcgctaaac cgtaattggt caccacgctc accgtgcggt
   128101 gcttttcggt aagggagcgc agcttgccca tgcccctctc cattagctta agtgactcct
   128161 cccagtccat gtccgcgtcc tggaaaaggt ccgggtagca ggacaccacg accatgccgc
   128221 ccttgttacg taccagctcg tcctccagag actcctcgac caaggtggac atctggtagg
   128281 cggtgaaggc ccgggacacg ttgatgctgt tcagcacctc ctccgggcgc agccggaagc
   128341 gtttgcacac gtacgtgaga tcatacggat tgacggagtt cccgccgtcc acccagacca
   128401 cgtcgcgatg ccattcgcgg acgaagttca cgctcagcat gttgaccaag ttgaacaata
   128461 atttgtcaga actgtcgatg gtggtgaccg ttcccggttc caatccgccg agcagttcgt
   128521 ccaccggagg tatggcggtg gtggccagca ttccatctgt cacggaatgc aggtcgtgga
   128581 ccagtggttc ggtcaccatc tcgggcatgg aacggtacat ctgctaaccg caccaacttc
   128641 gccttgaggg tataaaggac tgataggggg aggtgggtga aaatgggaaa taacataatt
   128701 ttcaagggag catgcatgaa aaggcgatgg cacattcgaa gaccacttcg ttacgagtaa
   128761 atagccgagg cggcattcta cggccgatgg atagggatgg gccttccgtt caattaggca
   128821 atggcatcga ggtcgcctgc ggcgacacca ggttcttcct cgatccgcgc agggtgtcca
   128881 cagagggcat atgctgcatc tcccacgccc actccgacca catgccatca agctttgcca
   128941 atggtccgat acactgctct gacatcaccc tgcgctgcat gcgcgggcga gtgaagagca
   129001 agaagtcaaa aactttcctg gaaggcgttg aattggggaa cgatccactg gtcaaggcca
   129061 gcggggccgg gcatatactc ggttccaaca tgttcctgct ggacgccggc cagaaggtcc
   129121 tgtacaccgg ggacttctgc ccgcaggacc gcctggacat cgagggcgcc aggccacaga
   129181 agtgcgacgt gctcatcgtc gaggccactt acggaaatcc tcgctacagg ttcccggacc
   129241 gccgggagat gatcaaggtc atacacgact gggtgggtga catgataaat caggggtact
   129301 cggccgtgct gcacgcatat ccgctaggca agtcccagga gctcatcacc atgctcaagg
   129361 atttccagcc ccgcctgcac ggttcggtgc tcgacaccac ccgactgctc gaatcggacg
   129421 acctcaagtt cgattacgtt cccttcgatc ccatggatag cgagccgcag ctggtcataa
   129481 gcccaggggc atggggcgag aacggtctga gcatgttgaa gaagaagcgt tccgcagacg
   129541 tttccggctg gtgcctggac aacggaggcc ggtccatggg caagatgagc tggggcatgg
   129601 accaaggttt cgcttactcc gatcacgccg atttctacga gataatcgat ttcgttgaga
   129661 aatgctctcc ctctctcgta tacacgaacc acggctccga ggacatgtta gcgcaggaga
   129721 tccagaagag gcttggcata accgccatcc cattgaagaa agagaagaaa ggtcagacca
   129781 atctgggatg ctattgctga gcgccccaca ttctcgggta ggtcccttcg ggcatgaaca
   129841 cccggacggt cttgacagcc ttacccttgt aagctttgta catgtcccgg gcggacatgt
   129901 ttgccgtccc taatcccaac gcctcgccct tcacggtgaa catggccacc ggagatcctt
   129961 tctccacgtt ctcgtccaag gataccacac cgggggcgtt gaggtccgcg ccgtgcgcta
   130021 tagcgtccac ggcatgatct ttgacgatga ccttaggtaa aggctccaag agcgcctcca
   130081 tgggccttat catggtccgc aaccacttct cgtcgccgtt cttccaatcc accacggcgt
   130141 ccttgaggtc ctgcatcgtt acggcatcaa gctcggtcat cgcgccggag cgcgtgcgtc
   130201 tcaacgccct catgttagcc cccacgccca atgcgtcgcc gatgtccacg catagcgtcc
   130261 ggatgtacgt cccggcgtcg cagtctacct tgaacagcac gtcccggccg gatatctcca
   130321 ggatatcgat ggaatggacc ttgcgtatgc gcatggcgac cttgaccgcc gagcgcaccg
   130381 ggggcgtttg ataaatggaa ccgacgaacg tctcgatgac cgaacgtact ttctcctcgg
   130441 ccactggccg atgcaggtac aggtggcaga cgtactgctt gttggaacgg aggaccaggt
   130501 cggtcattcg tatcgcttta cccaacgcta tcggcaggac gccgctgacg ttcggatcta
   130561 gcgtaccgcc gtgcccgatc ttctctacgc ccaggatgtc ccgtacccac gccgtgacct
   130621 gatgagaggt cggtccttgg accttatcta aaactatgac accgccgtcc agcagctcct
   130681 ggatggagcg gtcctcgggg cgttttcccc tttccaccac tctgggatct ttgtcccgga
   130741 ccagcatctc aaacgctcct tatccgggag acgatcgact cgaccacctg ctctggcgtc
   130801 agcgaaccgg tgtcgatgac catgtcgtag atggagcggt cggtcacgtc gatgtcatag
   130861 aacttgcggt accttagcac ttcgctcgcc tcgcgggaac acatctcgtc catggccgcc
   130921 ctcatgtcca cgccctcccg tccggatacg cgctccacgc gcacttccag aggggcgtcc
   130981 aaaaatatgc agaaggcggg aatgaaattg cggcggagca tctgtccggc caggcgacct
   131041 tcgagaatga cgttgtcctc gctcttagcg acgtccagca atcgttggtc gatcagcctg
   131101 tcgtacttgg ggtcctgctc ggccagatct ccgaactctt ccagtgacat gccaagctct
   131161 ttggccatct ccctgaacac aagtccggag atgaccgtgc ggtagccaag catgtcgcct
   131221 agcatgcggc acaccgtggt cttaccgctg ccgatcattc cgcttatggt gatcctcatt
   131281 gcccttcagc cttcaatacg ttcaaccgct tcttgaaggt gtaatacctc agacccctag
   131341 aaagcaattg cccgaacggg acgctgatca gggagtacag caacacccag gccggaagca
   131401 cgtatgactt gttcaggtcg gcgaagttgg accagggcac ggttatgacc gcgctgtcca
   131461 aattgccgac gaacaccgcc aaccaagcga atatcggtat gacgatgagc atggtcaccg
   131521 gcatcagctt catctgggag gtggtctgct tcatggactc ctccatcatc ttgggctgca
   131581 gttccatcat cttcttcagc ttgtaggtgt tgttctcctt gcgtgcggcg gacatctcct
   131641 tgttgaaggc gctcattatc ttctggcttc gggtctgctt cacgtagtcg gtgaagaagt
   131701 gcctcaccac gatgctcagg gtggtcatga acgcgccggt tatgaagaga gatacgaccg
   131761 ggatggagcc gtcgaagccc cagaggggct ccaggccgta tccgacgatc ttacctagtg
   131821 cggtcctaag gtctctatcg aacatcacga agatggccat gatgaagacg aagatcagca
   131881 gcatcctgct ggtcgtcgac ttgcggtccg tagccgggag ttcagccatc cttcatcact
   131941 ccccgccgaa gaatcccctc atcacagggt gcatctccat catctgctcg cgtcccatcg
   132001 cttcgtagaa ctggatcatg atgcccacgg acagcagcac accggtcccg ctggcgttac
   132061 caacggtacc tatgaggtcc gctcccgcgg ccagtccgcc caccagcgca ccggatatga
   132121 cggtcacgat ggggatgtac ctctccagga cgcgcttgag cacccggggg tcgcgacgga
   132181 aaccagggat ctgaagtccg gaggactcga tctgcctggc caccgcttcc ggtcccatgt
   132241 tggtggtcat tatccagaac ttggcgaaca ggacagaacc gccgaccata atgcccacgt
   132301 agaccaatac gtgcgcaatg acctgccagg tgctatgccc gtaaaccatg ttgccgtacg
   132361 atccggggtt caggatcggt aagagccaat cccccactcc gttaggggtg gataggtacc
   132421 aggccagacc tgacgtgggg tgcgtcgccc cagctggata gacgcccaat aacgggttgc
   132481 cgcccagcaa tggtatcccg ttcagcgcgt cgttcgtata gaacaacatg gtgaacatgc
   132541 ttatgttggc cagcagcgcg gccatcagga tgaccgggat gttggaggcg tagaccagtt
   132601 tgatcggata tcttccgcgt gctcccctcg ctgttccatg cgccaacggg agctctatgc
   132661 gtgacgattc gacgtaggcc acgaacagga atatgattat ggtaccgacc agcgcaatga
   132721 gcggattggg attggctatc aacatctgtt cgtaccctcc gcccaccagt tccgacgccg
   132781 attgatgcgt caggatgtag atggtcttcg gtatgctgcc tatcggcagg ttgctgttgc
   132841 tcagtggctg atccgtttgc aatccttcgg tgttcaaagt tccagtgaac agcgcttccg
   132901 ccactccggc ggcgatgaac aatgagatac cgctaccaat gccccatttg gacaccactt
   132961 cgtccatcag gaacaccagg tacgagccga cgcaaagttg aatgatgatg atcaacctgg
   133021 cgatgttctc tccccgcagg atcccggagt cgccgaacgt tccttccatg ccgccgacga
   133081 aggcgctgga aggaacgagg taaccgaaaa cctggggaat tgactccacc agtatcatca
   133141 caagaaccag gaacttctgg ctgctttgat agaccgcctt gtcttccttg ttcgtaaggt
   133201 ccaatttgat gatcttggcc cccacgaaca actgcatgat gatggaggcg gtgactatcg
   133261 ggccgatgcc cagatgcatg agcgaaccct gagcaccggc cagaatggcc cggtactggg
   133321 cgaagaggtc tatggtctta tctccgtcca gaccgtacag gaagatgttg gtcatgataa
   133381 agtaaaaaac cagtatcact acgacccaca gcatcttggt ccggaaatgg acgtgcccct
   133441 cgggtttgga gaccgccggg aggcggtctg taataggttt cagcttgtac agcttgctct
   133501 tctggtcatc ggccattggc atcacgtagt acttactctg gcaccacgat atgcccacct
   133561 gattcttcaa ccttagcctt ggccaagacg gtcgtctcgg cgactaagac cttgaaaggt
   133621 gtgctcactt ggccgttccc cagtagcttg tcgatgccca gggcggtgag gtcgagggtc
   133681 atcacaccat ctttctccac cgcggtccct tgagccttca tgacatccag tatctgctcc
   133741 agatctccca cgttcatggt gatcttggcg gataccatct tctgaggccg cttgaacccg
   133801 tgccggccaa agtggtcggg catgtatttc agcatgtact ggaccttgtg cttgtgcaag
   133861 ccggcgttgc ccttgccgcc gcgctttccg gccccacgtc cggccttctt gccgcggccg
   133921 tgggtcctgg agcctctgaa cttgtcggtt ctgctaacca ttcatatcac cttcagatca
   133981 tcctggagat gagatcgttt atctcctctc cccgatagcc cagggcgccc ccggccccga
   134041 aaccgcgctt tacgccctcg taccccttct tgggggggct caggcggaag atcggcttca
   134101 cgtccttcat gtccgagtac ttggtctcgc cattggatat tcccttggcg agggccatga
   134161 tcgaaccgaa gggggtgctg tccttgacca cttcatcatc gatgggcttg tcgcccatca
   134221 accggccgcg gaacttgatc atgcgggcca gggtctcatc cgaaacctcg ccccaggtga
   134281 tatagtcctt ggccttcatc agcatgccct ttatctcatc cgtctccgcg aggatcacgc
   134341 agtggttcgc cctggtgagg cgaagcatgc gcatggtatc ctcaacgtca tggcggacac
   134401 cggagtggcc gcgtacacgt atagctgcgt atgccatttt cactcctcct gtccgggagc
   134461 ggattgctct tccacatgca gctgcaccgg cccgctcact atgtgctgcc tcttctcctg
   134521 ctcctcggaa acgcgcatct cgatgctgtt cctcagggcg tagtaagttg cgtacgcata
   134581 gttgacggtg gtcttggtgt tcccccgggc gaatccccag gagtccttga cccccgcgag
   134641 cgtcagtatg ctcttggcca catcgcccac cgccagggat atacccctgg gggcgggttt
   134701 caggtagacc tccaccgagc cggacttgcc gaccacggtg aacggcagcg agtgcggcgt
   134761 accgcatccg cattcccaag agccgcatcc gcgcttgatc tcgatgatgt tcaacttggc
   134821 gttgtcgatg gccttgcgga tggagggacc aacctccttc cccttggccc ggccgatgcc
   134881 gatgaacccg tccccattgc cgaccacgca ggtgatccgg aacttgaccc tcctgccgga
   134941 gtcggtcatc ctctggacca tgctcacgtc gatgacctcg tccttcaggt cggggagcag
   135001 tatgtccacg atctccgcct cgcgcagggg gagcttggtg gccagggcct ggctcatggt
   135061 ggttatctca ccgttgagca ccatctttcc cagtctggtc ttcggtaccc aatccatctc
   135121 agttcgcctc catgcgggtc ttgatgtcct tgatcatttt ttccacgtcg tcgccgatgt
   135181 tctttccggc aaggcgctcc ttgctgggca gaacctcttt gccgtggggt atcttcattc
   135241 cggcgtccac catgcccttc agggcggcga acaccgtggc acccttggcg ggcaccttga
   135301 gtccgatgtc tagcacggcc tcgcttattc ccttggccat ggccttcttc ccggccaggt
   135361 acccggtcag gtacgcggcg ggaacgttcc cggtggcctt gttccatccc atctccagca
   135421 gctcgcggga gtgggcggtc gccaggacct ggtccccctg gggatcgaag tccacgatct
   135481 gtatgctgac atggcgtagg gagacgcgta cgacggcacg cggaaccctg gccctcagca
   135541 gcctctgcct ctgtctgtag tcagtgcgtc cctcgcgccg gcggcggaag gccactctat
   135601 atctcggtcc ttgcgccatc agttatcccc cttgaggtag ccttcggtct tcaggtgcat
   135661 gagcaggttg ttcctgctcc tgaacatgcc gcccttggcc ttcatgtaga attcgcggta
   135721 aacgctcctg gtgatcgtgc cctcgtcacg caactgtcgc agcgtggcgc gcaggggcct
   135781 gatcgtctgg atccaggcct ccttcttcgg ccttctggcc ctggaggtac ctttcctgct
   135841 gccctgtcca cgccggcgtc ccttggcctt ctgggccagc cggtggcggg cccgtcctcg
   135901 ggagatgccc tgtttgggca aggcgcggat ggtcccggac aggatggctg tccttatgtc
   135961 cgcccgggtt atggcgtctg cgacatcctc tatgcggtta gggtctatcc agacccggtt
   136021 ctcaccgcat ttcaagactt cggccgccat gcgcttctgg ttcttgagat ccatctgttt
   136081 cacgtcctgt tcaatacgcg gatgcttagc tcatccgcct tctcgattat tgccattctc
   136141 ttcttcccgc ccacggtgcc gcctatgcgt atcgcttgca ccttggggtc tacggcctcc
   136201 acttggccag ggttgtacac catgacctcc tggaatccgg aggggtggta gtcgcgcacc
   136261 atcttcgggc cgcggaaacc gatcgagacg accggcgggc ggtaagacag gtgtcttcgc
   136321 atcttggagt ggatgcccct gggcttcctc cacatctccc cgagcctctg gtaccggaac
   136381 cactcctgcc tcttgaatgc ggggcgggcg tcgttcttgg cgctcctgaa ctccagggcg
   136441 gccttgatct cgtcgttgag gaccggtttg accttgacta cggtcttctc ctcctcatct
   136501 acgatctccg tttcggcctc ggtttcgctg agaagctcca gccagtggtc ggcgatcttg
   136561 ttgccgacac cgtccagatc gtccacgatg accttcttac ggtccttgtc cttcagcgcc
   136621 tccaggagct cgtccagctc ctttatgccc agatcggcca gctgagcggt gtattcctcc
   136681 cggtagtagg ggaggtcctg tatcttgttg atctccttct tggccgccat tacttcggcc
   136741 tccttgcctt ctctacaatg tagataccat cctggaagac ccggggatcg aatcctctga
   136801 tcttggtggc gcgttcgatg ttggcggcgg tctgcgagac cttctccagg tcggagccgg
   136861 tgacgaagac ctcggcgccc ttgatgctga ccttcgctcc ggccagtata ggcgcggagc
   136921 gcggagcctt ctctcccagg aagttctcga tgatgaaccg gtcgcccttc accgcgatct
   136981 tcatggggaa gtgagagtag accatcttca tggcgtactc gaacccgtgg ttagcaccct
   137041 ctaccatgtt cttcaggtga gaggcgtagg tcccgaccaa ggccttctcc ttggtgcggg
   137101 gatactcgca ctccacgtgg aaatggtctc ccttgaaggt gacggtcacc ttagggtggc
   137161 tgaagtccct ggttactgtg cccttcggtc cctttacggt gacctcggcc cccttcatgg
   137221 tgacctttac ttccttaggc acgtgcacct tgtcgtccaa atgtccggtt acagtcattt
   137281 aaatccctca gtacacgaac gcgagcagct tcccgcccac gcccttctcc ttggcttcca
   137341 tgtgggttat cacgccgtcg gtggtggtca gtatcaacac gccgaagtcc tgggccggta
   137401 ggtaccgggc ctcgaactgc tccatgttta ccttcttaac cgagtagcgc ggcttgatca
   137461 cgccgcagtt gttgatcctg ccttccagca tgaccttgaa cactccggcc tttccgtcct
   137521 ctatgaactc gaactggttg atgtagccgt tgtcctgcat caccttgagg acccggccga
   137581 tcagtttcga ggagggcctt atcacgcact cgctcttgcc cacggccgcg gcgttcttga
   137641 tggtggacat cgcatcattc aatggatcgc tctgcatttt tttcacctca tgagtacttc
   137701 ttgaacccta tctgcggtgc gatctccctg aagcattgcc ggcagaggtg cataccatac
   137761 cggcggacta tgccccgctt gcggccgcac ctggtgcagc ctacgcttct tccgaacttc
   137821 ttcttgggct tcaatcgatc acctcaacgt tgaacttctg tttgatgaac tccatggcct
   137881 caggcctggt catgcggtgg gtgtggggta tggagcggcg catcacgcgg cgcctggcca
   137941 cacgcttccc gggcctctgg atggacacgc tgatgtccat gccgaagatc ccgatctcag
   138001 ggtcgtactt catcccggag aagtcggtat agtccggcac tccgaaggac aggttgcctt
   138061 cgcggtcaaa ggagtaggag gcgatgcggt tctcacggat ggtgaacgcc ctcttcagga
   138121 aatcatcggc cttcgctccc ctaagggtga cgacgcatcc gatgggctgt ccctcgcgga
   138181 tgccccagtc gcggttggtc accttggata cggtctgctt ggacttctgt cccgtgacca
   138241 tctcgatgac cttctgtgcc ttgatcaggc ggtcaccgga ctcgccaact cccatgttga
   138301 cgactacctt ctcgatgcgc ggcaggcgca tgatgttctc gctcataccg ctctcacctc
   138361 gggtagtacg acctcagggg tcttgttgcc gatcacgaac acgttgtcct tcacggtcag
   138421 cttgccgttc ttgaagcgga ccaggttggg ggcggtggag cgctcctcga tctgctcgtc
   138481 caccacgttg atctgtccgg cgttggcgcc gctgacgatc atggccacgt tgccctggac
   138541 cagcttgaag gcctctatga ccttctgggt cggcagctcg atcttcagta cgtcgccggt
   138601 cttgtagatg tccgattcga ccaacatgtt gcgcccgtcg tgcaggttca actgtaggcg
   138661 gccgccggaa acgtaggtct tgttctcgat gcggcacagc ttccacttgg cgcggtcctc
   138721 ggttatctcc actagtatga acttgccgcg gtcgtccaac agcatgcggt agtgcttgcc
   138781 gttggcgggg atgctgacga cgtccatcag acccaccggg aacttctcct cggttatgac
   138841 cttgccgtcc accagtacct tcttcgagga aagtactttc ttggcctcgg cggcggtgtc
   138901 cactaccttc agcatgtccc tcaggaccac gctcaaaggc atgcatccgt ccagcgagtg
   138961 cggaccgggg ttggggctgg tcacccatac atggctcttc ctggtcaccg gccagctctt
   139021 cggtgcatta agtctcttca gatcttgggt cactgggaac cctcctcata ttgcagcttc
   139081 tgcttgcggt agttgtcctt caggtccaac ttggtaacga ccacgttgga cgcgtgcacc
   139141 ggccgctcgg tcatggtgcc gtcggccttg gctatggtga cgccctccac gatcagcttg
   139201 ccgttgtggg tatcgacgct ggtcaccttg ccctcggagc cgagtatgtc ctcgtccccg
   139261 cggaccaccc ttacagtgtc tcccttgacc acgcgtacgg tgcggcggcc cagcttcttg
   139321 atcagctctt cgctgaggtg ggagccgacg ctcttgttgc gcacatggtt gggggcgtta
   139381 aacagcgcct tcctctgctt tcttgcgtgc ttgctcgtca tttcctacac ctcacactat
   139441 ggtcgatgcg gtggcggcta cgcgcggcca gcgctcggcg gcctctctgg ccaccggtcc
   139501 ctttatgtcg cttcccttgg tctcgccctc ttcggtggtt atgaccgcgg cgttgtcctc
   139561 aaagtgcacc atggtgccgt ccgcgcggcg gaacggcctc ctctggcgaa cgatgatggc
   139621 gtagacgacc tgtctcctca tttccggagt tcccttcttt acggaggcga cgactatatc
   139681 gccaaccgcg gcggccgggc agcgcccgtg cacaccgtgg tagttgggga cggcgatgac
   139741 gctgatgacc ttggcgccgg tgttgtccac tacgtccagg tgcgatccgg ttatgatgcc
   139801 cctggtctgg ttacctgcca atcccttcat gtcctcacct cttctccacg acgacgaagg
   139861 acaccgtctt gctcaagggg cggcattcca tgatgcgcac cttgtccccg gccgctatct
   139921 ccaggcaggg ggggttgtgg gcggtgtagc gcctcgtcct cttttcgaat cgttcgtact
   139981 tcttgtcata tttcaagtag ttcctctcga ccacggcgct tccgttcatc ttgacggata
   140041 ctatgacgcc gtcaatgatc tgcccccgaa ctgggagctg cccgtggaat ggacagtgct
   140101 tgtcctcgca ggtggccgag ggggccttga catcaatgcc aatgtctctg acttcgctca
   140161 ttagatcacc taattctctt gatcctatcc tctggtcgat gctggatctc ggatcctagg
   140221 accctgatcc tctcgccctg gtatgtgaac acgaactcat ggccggactt gggtatccac
   140281 ctctccctgc cctggcagga tatggcaaac atgttcttgg tctcgtccac caccttcccg
   140341 tgcaacaggt gcccggggca gctggattcc accacctcga tgtccagtcc tatgaattct
   140401 tgtctcatga aatccctctg gtccatggct cctaccgaac ctcggtcttg aagcccatct
   140461 cttccagggt ctgagccact ttcttcttgt ggtcgccctg gagctcgatc ttgccttctt
   140521 tggcggtgcc gccggcggcg cacttgttct tcaacttgcg cgccagatca tcgatgtcta
   140581 tgtcggtgga atcgatccca tcgaccacgg tgacgatctt tccgtagcgc cggctgtcgg
   140641 tgtagatcct aacggactgc tgttctctgg cgatctcctc gcacatgcac agctctttag
   140701 ggagcccaca taccgagcaa atgtcggcca ttattgttct tcctccttct ggacggttag
   140761 gatcctggcg atgttgctcc ttaaagccct gatcttcccc gggttgttgg gtgccccgcc
   140821 catggcggcg gcccccttct cgtgcatgag ctcgtcctgc agctcgcgga gcttggcagc
   140881 gcgctcatcc acgctcatct ctcgtatttc agaggtcctt agtaatgcca tttattcggt
   140941 cacctccttc ttgtcgctct cggccggggc ttcgtcctcg gccgggtgct cagcgatgac
   141001 cgacgcctcc tccagtttct tcagaaggtc gacgaggtcg gggttggcct gcatggccat
   141061 ctccatgggc atgacgtcga tctcggccgg gaggtgtgct ccgggctgca tgatctcgac
   141121 ctgtaccccg attaccccgg gcttcagctt ggccacggcg aaaccggtac cgatgaacag
   141181 gttcctggtc tcaccgcagt acttgatcga tccctctttg aacttctcgg tgcggtgcct
   141241 ctctccggtc agcttgccgg agatgattat aaggcaaccg cgggcgccgg actccattat
   141301 gcggcggacg gtcgagtgac cggcccgcct gaagtgccag ccgcgctcca gggcgaaggc
   141361 caacttctcc gccatgatct gggcgttaag gttggggttc tccacttcct ggacctcgat
   141421 ctgggggttg tcgtagtgga acttgtcctc gatgtccttg gtcagggtct tgatggccgc
   141481 tccgcggcgg ccgatgacta tgcccgggcg ctcgacgacc agggacaccc tggttcccat
   141541 gggggtcctc tgaacttcca cgcctccaaa gccagcgcgg tctacggtcc tcatcagatg
   141601 ctccttgagg agcaccctcc tgatgttctc ctgtgtgaac ttcctctcgc tggccatcta
   141661 ctgaacctcc tctaatatga cctcgatgtt gaccgtctgt tggttccagg cggtgctgcg
   141721 gccatgcgcc ctcggcatgt agccggggat ggtccgtcca aggtgggcgg agactatgcg
   141781 cacgcgcatg ttgtcggcat ccaggccctt gtactccgcg ttgctcttgg cgctctgcag
   141841 caccctgatg atggcggcgg cggccttctt cgggaatcta cccggtccca caccggtctt
   141901 gtgcgccacg ccgaagttgt ggcggcggat cggcaccggg cggcgcagtt ccactacctc
   141961 ttccagcatt tggatggcga catcgacctt cttgcccctt atcatgcggc agatctctct
   142021 cgagaacttg ggtgagatgg gcagttcctt tgcgatagcc ttggacgtgg tgtccggatc
   142081 ggcttctgat gtgtatccta ccattttttt cacctcactt cagcggcatg aacttggagc
   142141 ccctggtcgc accgacgccc ggaccggagt gctttacaga tcccctggtc atggcgaact
   142201 cgcccaagaa gtgcccgatc atctcgggct ttatctccac ttctttgaat tccttaccgt
   142261 tatatacggc cacgcggcgt cctacgaagg acggcacgat gggtatgtca cggcggtgcg
   142321 ttcgcaccac ttcctgctct ccatccacga tcttatcgta ggtggtcttc tgctcctcgt
   142381 tgagtccgcg gcggaacgac cttctaaccc tagacggcag gaggtcgacc atttcctcga
   142441 agggcatctc caggagctgc tccatggtga atccgcggta ggtgaactcc ttcttcctac
   142501 gggcggtcat catgcccttc ttcttccgct gcttcctcct cgaggccttg gtaccagtta
   142561 gcttatcttc agccatctag aatcacttcc tcttcttttg gggggaaagt cttcctacct
   142621 tccttcccgg cggagcgttc ctcgaaaccg tgctgggctt accaacgtgc gggtgacctc
   142681 caccgccgtg cgggtggtcg acggcgttca tcgccactcc cttcaccttg aagtaggcct
   142741 tgctcttgct gcggtaggcg tggaacttct ttcctgcctt ggcgaagggc ttctcggaag
   142801 ccccgccgcc cgctacgatc cccacgccgg cgcggcagcg ggggtcgaag ttcttgaatg
   142861 ccccggaggg cagttgcacc aggacggtgt cgcccttggt gaccacggtg gcgtagttac
   142921 cggcggtcct tacgaacttg ccgccatcgc caggcctggc ctccaggttg tagatcaggg
   142981 taccctcggg gatgttggcc aggggcatga tgctcccggg cgtcaggctc agggagccgt
   143041 ccacgctgat atcctgtccg accatcagcc cttcgacggc gatgatcttt tccttcttac
   143101 cgtcctcgaa ctggacctcg gccaccgggc tgttccggcc aggggcgtgt attatgtccg
   143161 ttacctttcc ggtcttgagc tcgacgtacg ggtgcttgat ctctcccacg tgcctgtggc
   143221 tcggggaagt ataggtcatg gtcccacgac ctcttctctg ttgtctcagt tgtctgccca
   143281 tgttccccct cctcagaaca ctccgatcct catgccgatg tcctcggcag agtatccttc
   143341 agccaatttg aatatggcgt gcttgccgtc cttggatatc ttggtccaga ccttgtccac
   143401 cttgacctcg aagtgcgtct cgaaggcgct cttgatctcc gccttgctgg cgaagcggtc
   143461 cacgatgaac tcgatcttgt tgccatcctt gaaatcctgg gtaggcgtgc cggtcatgta
   143521 gttcatggtc ttttcagtca cgtacgggta aagcaatacc ttcctggcca tgctcaccac
   143581 tctcctatct tctttatggc ggcctcagtg aacaccgtca gccggccggg cagtccgccg
   143641 ggggctaggg ttccagggtt cagcatatcc gcgaaggcca cctcgacgcc agctaggttc
   143701 ctggcaccct tgatcaccgc ggcgtctttg gtcgagacca cgatgagcag gctgcggggc
   143761 atccggtagg gtctgccacg catcttgccg cgtcccggcc tgatccttat gccgtccttg
   143821 gcccggatca catcgtcgga cacaccgatg ctcttcagga cgtccaaaac ctcggaggtg
   143881 ctcttcacgt cctccatgcg gtcctctatg accactggaa gggtcagccc ctcgttgaag
   143941 cggtggcccc tggccctgac cttctcctcg tcagccgttg cggccagcgc ggagaacttg
   144001 gcaagggtct tctccttctg gttgaccttc atggtccaga ccttctcgac ccggggcggg
   144061 tgggcgcggc gacctccaac gttgttgggg gactcggcac ccttggaccc cgaggacagt
   144121 ctctgaacgc gggccacacc tcggcccttg ccccaggtgg acaccgagtg ccttattccg
   144181 gcgcccggct tcggtccgta gggttgcctc ttgttggact cctcggcgac cacggcccgg
   144241 tggatgacgt ctggcctgaa ctcggtggag aacacctcgg gcagagcctc ggtcctcagg
   144301 acctcgccgt tcattgaata tacgtttact ttggacattg cttacgcccc ctgcttggac
   144361 tcggtggaaa tgtacaccat ctccggcgct tccttcaggt ctggcttttg ccttctgacc
   144421 gggtccctca tccgaatcag cctcttggtg gggccgggta cggatccgtg gaccagaacg
   144481 aaggggttcc taacttctcc gtagtgcagg aaaccgccct tggggttgat ctcctgaccg
   144541 ctctctccta ccttcagtat gagcttgttg acctcggtcc tctggtggta acccatctga
   144601 ccggactggg gcacggtcgt gcgcacgtag ccaggccgct tagggcccag gttaccgatg
   144661 gcgcggcggt gcttggagtt cttgtgggac atgagcttca ggccccagcg cttggtggcg
   144721 ccctggaaac cctttccctt ggttatggca acgacatcga tcatcgcgcc agtgttggcg
   144781 aagtcggtga tggcgatgtc ctttcccaaa agtcccttgg cgaaatcgac cctggcatcc
   144841 atggtgccgc cgcctatgcg cagctccatg agctccgggc gcttcttcgg cactccggtg
   144901 accagcttcg gctgggtgaa ggcgagcacc ctaacatctt cggtgtccac tcccttcagc
   144961 ttctcccaga ccgcatcggc gtcgaccttc ttggggatag gcagcagcct ggagagagtc
   145021 tcatccagct gggtcgccca gatctcccct gcggtcttga gcccgtagcg ggtgttctcg
   145081 tagatgcgta ccgcggccac cttcatggga ggaacctcca gaacggtgac gggcaccctg
   145141 atctcctgac cggaggtggt gctggtcttg cggcggtcca cgatgaacgc gtgggtcatt
   145201 cctgccttgt aaccggcaaa tccctggacc ttcgggcctt cgctgatatc gggccacgaa
   145261 tccagccttg gggtctgggt gatggccctc ttcctaggac cgaatccctt tgaccccctt
   145321 ctcggacgtc ttatgttcga catgcttctc cctctatttt tcctgagaga gcacactctc
   145381 tttcgctaac gcctgttctc aagagtgttg aggctagcac cttcgaccgt gacaccgtca
   145441 tcaccctcca gaatgtgctt ttgggggcga cttagggatg ctttcgcatt gcccaagggg
   145501 tctggtcgaa cgtcctcagt gcgttgagca gaagtccgat actatcattc ttatttaaac
   145561 caatcggtcc accgtatata aagagtcatg gggaaaaggg gtttgctgga tgcgctcaga
   145621 gcttgccttc cttggccttc ttctgcaagc ggttgcggcg ctccttggat gagaagccgg
   145681 tggccttctc aaggaactcg ttccacttct tgatggtgtc cgcggcgagg tccggggaag
   145741 cgttcttgtc gctggtggcg ctgatgtcca tggaggtctt gctgacgatg cgcacctcga
   145801 tcctggtcat ggcaccatag gaggagatca gaacgtcccc ctccaccttg accgacccaa
   145861 aggaggcttc catgatcttc ttcagtccgt ccccttccaa tttcccgtag ttacccttct
   145921 tgatatcgta atccatgtga atccctctaa agtctcagat catcatccag gtatcggtgc
   145981 acatcgaccg aggtgcgcat cgcgtcctcc gtgcggagga gggacgccca ctcccggcgg
   146041 cactgacaat cgtgtttatc caataatgaa gcgtcctgct cgaagttgaa cttttccaat
   146101 acgtccagca agcgtcggtc gcattcgggg cagttgtgca cgccgcgcgg cgtccctggt
   146161 ccgctggggg aggagaacag ccttacgccc gatatctccg acctcagttt caggacctcg
   146221 aacagggacc agatccacgg cggccggtaa tcgccgcgct tccacagtcc ttccaccgcg
   146281 gtctccttct gaacgttgag cggattgacc gaaatgctct cggaacgagc ggcggcaaag
   146341 tgaacggacg ccttggtatc ctcgatggcc gccctctctg tcaggtacgg gggcttgagc
   146401 aacaggtatg tccgcaccgg aagtccccgg tcgttgagag cgtcggccgc tctaacgtaa
   146461 tccttcaccc cgaacccctt gcgcacggaa caccgcaaca ccgtatcatt ggcgctttcc
   146521 agtcccaagg ccaccgcgga atggtccggc aaatccttga gcacctcggg ggtcacgaac
   146581 tccgggcggc tctcgaagag caccctgcgc gccccatcga acgcgttcag tatgcggtcc
   146641 cgaaccacca gaggtatctc gttggggtcc aggaagctcc cggaagtata cagcttgacc
   146701 atcccctcgc cctcgtacct ttcgaggatg gcgcttagct gggcggagat ctcctcaggt
   146761 ccgatgccct ccaggctttc aacgttatat ccgcacatgg agcacccgcc cgtgcgtgac
   146821 cagtggcagc cgcgggtgcg gaagatggcc accagtgcct tctccttcct cccgtcgacc
   146881 acatcctcct ctttccagac cgtgaccggt ctgttcaggt ccatgctctt catgattgct
   146941 ccatgcgaat gaaggtcaaa tcgcccctaa ctatttgagc gctccgacgg acgataccaa
   147001 cattttatat cctcacttca ggatttgcgg cctggagaag catcatggcc aggaagatag
   147061 tggttatcgg gggaggggcg gccggcatga ccgcggcctc caccgccagg gagaacgggg
   147121 ctggggacat caccctcatc accgaggacg aacacgtggc gtactcgccc tgtgccatac
   147181 cgttcgtcgt ggaaggcacg ataaaggact tcccgagcat tgtgatgcac actcccgagt
   147241 actatcggcg agagaggggc atcgaggttc tggtaaagac caccgtggac cgcgtggacg
   147301 ccgaggccaa gaaggtgatc accaaggacg gccgctcctt cgattacgat tctctggtga
   147361 tagccaccgg cggaacggtg ttcgtgccgt ccatcgaggg acgcgagctg cacggcgttt
   147421 tcccggtcag atggatatcg gacgggcagg ctatagtgga ctggcttccg agcaccacgc
   147481 aggtcgtcgt cgccggagcc ggggttatcg ggttggagat ggccgtagcc ctgcgggaaa
   147541 gaggcaagga tgtttcggta atagagatgt tcgaccaggt ggtcccccgc atcatggaca
   147601 aggacatggc gcagctggtc caagcgcact gcgaggcgca gggcatcaag ttcgttctcg
   147661 gttcgccatg ctcgtgcatc gagggcgatg agaaggtcac cggggtcacc gccggcaaga
   147721 cgcatatccc ctgtcagatg gtcatcatgg ccaccggtgt gcgagcgaac ctgcgcatac
   147781 ccgagcagtt ggggttggag atcggtcccc tgggcgcggt gagggtaagt ccaagcctgc
   147841 agccctaccg caaggggcgc ctggtgccag atatctatct ggcgggtgac gtggtcatgt
   147901 gtcagagcgc ggttctagct ggaccgacca tgagccagct gggttccacc gccgtccgtc
   147961 aggggcgggt ggccggaatt cgggccaccg gcggcaatgc caccttcccg gggaccgcca
   148021 gtccatatgt cagtgtcatc gggggcttgc aggtcggcgg aaccgggatg tcccgttcgc
   148081 tggccgagta ctacggggtg agggtggtag agtccatggc gaaaggctcg tcccgggccc
   148141 ggtactatcc gggcgggaag gacatgaccg tcaagctact ggcggacgcc gagagcggac
   148201 gtctcatcgg cggccagatc gtgggcgggg aggatgtcac cggacgggtg aactggatca
   148261 ccgccgccat actggaaggt gtgacggtcg cctcgttcgt ggagaggatg gagaacgcct
   148321 actgcccccc cacctccatg gtcagcgaca cggtgaacgt ggctgcggag aagctggcca
   148381 ggacgcttcg cggctgaagg ccaatctgtt taatattccg ttccacattc gacaccggtt
   148441 aacatggacg tcgaggagcg gtacgcatta gtggcccgga acaccgagga gatcatcacc
   148501 ccggaggacc tgatggaggt cctgcggaac aaggactccc ccactggtta tatcggcttc
   148561 gagccctccg ggctggtcca cataggttgg atggtcaccg ctcagaaggt aaaggacttc
   148621 gtggacgccg gattcacctt cattgtcttc ctggccgact ggcacgccta tatcaacgac
   148681 aagctgggcg ggaacatcga caacattcgg atatgcgccg agtacatgaa ggactgcttc
   148741 gaggcgctag gtctgccgag ggagaaggtg gagtaccgtc tggcctcgga gataatggac
   148801 gatatcgatt attgggagac ggtcatgaag gtaggaaagg cctcatccct gcagagggtg
   148861 aagcgagcca tgaccatcat gggccgcaac gaggacgagg ccgaggtgga ctccagcaag
   148921 accatgtatc ccttgatgca ggcggccgac ctgatattca tggacgtgga tgtggcctac
   148981 gccggtctcg accaacgaag ggcgcacatg ctggccagag aggccgcgga gaagatgggg
   149041 gtcaagaagg cggtggccgt gcacactcct ttactccccg gtctcaaggg cggcaaccgc
   149101 atggaccccg tgagctcgaa aatgtccaag agcgatcccg agggcagcct gctcattcac
   149161 gattccatcg aggatatcaa gcgcaagatg ggcaaggcct tctgcccccc ggaggcggag
   149221 ggcaacccgg tactggcgat atgcaagtac gtcatattcc agaggacctc cgtcatgcgc
   149281 ttcgagcggc cggagaagtt cggtggcgat ctggagttca agagctatga tgagctggag
   149341 ctcacttact tggctgggaa gctgcacccc atggacctga agaacgggac cgccgccgct
   149401 ctcgccgata tattggcgcc gaccagggag tacttcgtga ggaagccgga gaacctggaa
   149461 cggataaggc aggttctgtc agaggtaaag aagctgcgct gacctcattt cagctttcgc
   149521 aggaaggcca tcgacttctg caggcatatg ttcagtatgg cctccgcgtc gccgatgccg
   149581 accaggccgg ccgctccgcc gtggccgcca ccatcattgt ccgtttcgtt cccgacgtca
   149641 ccgagaagct gtccaagatg caggcccttg cgcaccaggt cctgccgggc ccgggcgctc
   149701 aaacggaact cctggtcccg ctgcgaggct acgaacgcga tgtccgcgcc gagcgagagc
   149761 atcgatttgc acaccgacga ttcgaaggag ctgccttggg atatcgcgac tatgtaaccg
   149821 ccgacccgtt cgaagcgcat gcgctgtcct cccttcatct gggccaccct ctccgatatg
   149881 tcggtcggcg agtcggtcag ggaaagcacg tcctccatgt tgaccccggc cgcctctatc
   149941 agacgggcga aggtccgcaa ggaatctgga tttgcgaagc gaaagtgccc ggtgtcggtc
   150001 aggatcccgg cgcacagccc cagggtcatc tccttgctga gcggtctccc ggcccgatct
   150061 ataatgtcaa gaacgacctc cgcgcagctg cgtttgctct catcgcacag atacgttccg
   150121 cgttccgccc acttgttcgt cgggcagtgg tggtctatga tgatcatctc gccctgcatt
   150181 tggctgtaac ttcccagctg ctcaggggag gaggtgtcca ccaccactat cagagggtag
   150241 ctgcgttccg gccgggtgag aagttccatg cccaggcggg ccgagacgtt cttggaggtg
   150301 cggtccagcc cctccacggg aagtatgtcc gccggcggaa aggccttggc caatgcgtaa
   150361 gcgctgccta gggcgtccgg gtcagcattg ccgtgaacca ggatgatctt gtccgaggag
   150421 gacagcctgg atatgatgtc gtcgagcatc caaggacgcc aatgtttcct ggctatatgc
   150481 aatttatctt agagaaaggg aagtggtttg atgatcggga tcagttatcg tcctcgtcca
   150541 tcttgagcgg ggcgccctgc tgctgagcgc cgagcgcacg gttcaactgc tcctgaacgc
   150601 tctggaactt ctccttgagc atcttctcct ggcggtccag gctcttgacg cggatctcgg
   150661 tggtctcctt gtcgtcctct atctccttca gtagggcggg ggtgtctgcc accttgatca
   150721 tcagggagcc gacgctcttg aacaccgtcg tctccgccgg gaccttcttc agctcctcca
   150781 aggtcatctc catctctttc agcatggcgt ccatcctaat cttctggttc atgaccgtct
   150841 gaagctgctg ctggagctgc tggaactggg cgatctgatt ttgaagtttt gggctcatct
   150901 catccatcgt tttcaccgac cgtttcactc atcttctctg ctatgctcat ccatcggatg
   150961 taggaattta aagctgccct gagggccgac aggtcgtcgg cgtccaaggt cagggtcatg
   151021 gacccttcgg acgcggagac tgcggccctg gtgcgtggta tctctcttcc ggcctccggg
   151081 ctgatcgccc tcgccacgtt agaggcgaag ggagagctca ccgccagggt ggcccggaac
   151141 atatctaccg gccctttatg accttcttga cgttgggccg ctccttgtag aacagcttgg
   151201 agccgcagct ctcgcactgt ataccgacct gattgaggtt ggagcgggtg gtcttttcgc
   151261 actgggcgca cttgtagttc aattgattca ctccttggcg tgggcggcca gtatctcctt
   151321 ggacacggcc tctctggtcc tgggggagta acaagcggcg gcgaacttgg cctcgcaatg
   151381 cctgcaggcc cagatcccgg acgcgactct cttgacacta acgtggtggc agctggggca
   151441 ctcgaacctg gaccgctggg tcttctcgat gtccctggtc agcttcctga cgaccacacc
   151501 gtacctggct ccatatcttc cggagcttcc tgcctttact gttctctttg ccattggaat
   151561 cacccgataa gctttctaat ctcaatgccc aatctgcggg aggtctcgat cgccgtcttg
   151621 acctgttcca acgttagcgc cccggtcagc cctttctgca tggcccggag gtctccattg
   151681 tcatcagtgg taacggtcag cctagctgtt gcgacctttt cttcgtcgag agtcgggtca
   151741 actaataaag agttttctat ctgcatcgag gtgatagaga tcggcgtgca ggtggtaggc
   151801 atcgggtagt cctcgcctag gccattggcc ttggccggaa cgatggcgct cttgatggcg
   151861 gcgaccgcac ccaggctgca ggcgtcgaac aggttaccgt cgaagtccag gacgtagatg
   151921 tccacgaagt ttatccagac cttcttgccc ggttcgatgc acaacttctc gaggtctatc
   151981 atctggcttt cccggatgcc acggtcgacg accctggaca gctcgatgga ctccgggtcc
   152041 ggaggtccag actcgaagct gggggaggcc atcggaatga gctcggcgtt ggtggacaga
   152101 actcccttgt taggggtgtc cgagaacggc tcccccacgg tcatcttgac accgactatt
   152161 acctcggtgt tgcctatctt gacccgggag gacccctcgg cggtctccac gacgttggtc
   152221 tgtattgata tctcgcggac ctggtcccag gcccttccgt caacgcgctt tccgtcggcg
   152281 ataagcttgt ggatgtggtc cctcttgatc tcggaaacta tggatcttgc catcttcagg
   152341 cctcctcgat tacgtcctca gcaggttcct tgggctcttc ctcggcctct ccgttgacga
   152401 tagcgtagcg gcggcgcaag gcgtccttct gcagagcgta tatctcatgg caggccttga
   152461 cgcccatctc cagggcctgg tcgaactccg cctgggtcag gtgcccgtcc atctgcatca
   152521 gcaatacctc gccggtgcgg gggatcatgg ctatcggcag atcggcctga ccgtagttgt
   152581 cctcctcctt gttcaggtcc aggaccacct ggtcgttgac ctttccgacg gcgacggcgg
   152641 ggaccaggtc cttcatcggt atcccggcat cggccagggc caccgcggcc gcgaccagcc
   152701 cggcgcatct ggtgccggca ttggcctgca gtacctctat gtacacatca atggaagtgc
   152761 gggggtagtt ctcggtgaac accacgtact ccatggcctc ggatatcagc ttggatatct
   152821 ccaccgagcg gcggtccggt ccgggcctct tgcggtccga gacggagaag gatatcatgt
   152881 tgtacttgca ctggacaatg gccttggccg ggttctgcat gtgtcggggg tggcactccc
   152941 ttggtccgta gacggctgcc aacaccttgt tcttccctat ctccacatac gcagagccat
   153001 cggcgctctt gagcactccg gcctcgatct tcatcggccg gagctcatct accttccggc
   153061 cgtctatcct tataccattt tcatcgatga gcttcatatc agaatttcca cccatttaaa
   153121 acacctcact cttccttgcg atataccgat tccaggaatt cctttacccg ctcggtcagt
   153181 ttcagggtct gcgctccctc gtctatcatc tttatggcct gcatggcgtg caccatgtcc
   153241 tccatgttac cgtccatcca tatcctgccg ttctgtccga tgaagatgcg gcagttggtg
   153301 taggtcttga tcatctggat catggagccg ttctttccga tcacacgggg caccttgctg
   153361 tgggagatct ccacgatctg tcctccctgc agcttgcgga gcccctgctc cttcatggtg
   153421 acctgcaccc tcttggtctc gtccaccgac aggaccttgg ccagcaaagt gtcgccgacc
   153481 gacaggtaac gggcggtgtc accgaactcg acgcgccacg gaacctcgtt cacgtgcagg
   153541 ggcgccgggt agggcgagaa tatgtccacc agccagttgg aaggtccgat atcgatgacc
   153601 ttaccgatga tcatgtcccc gggggccggt atgtacctgc cgcccagcgg gatgacgttc
   153661 acaaagttcg acttgacgct cttgatgccc agcatcgcag cgaagatctt gccatcactg
   153721 acaaaggtcc cctcgccagg cttcatggtc ccgtcgtcca gaaggtctcc gggaagcacc
   153781 agttctctgg tcatgctctc attgttcatt ttatcactct tggaatgtta taggtcattt
   153841 cttcagctgc ttggtctcta cttcgccatg ggtcttggcg ttcaggcggt ggaacaggtc
   153901 gtcgcgaaga ccggcgggta tctccaccac gccgatccaa tcaccgttct tctgccattc
   153961 ttcattggtt atcttgccca tctccttcat gtcatcgtag cagcggccat attcgtcggc
   154021 cttcagcttg acggctatgc gcaccgtgtc aaagcgtatc ggtatcaatg gacgcagctt
   154081 gtccattacc tgctgcacct gtacgtccac cggcttgaag gcatcgatgt ggaccttggc
   154141 ctcttccatg gccatctcta ttcgcgccgg ggtgtgtggg ccgccggtct gcgggtttat
   154201 ggcgttgcgg gcgatggtgg ctattatgcg aagccgcttg ctctccagca tctccttgcg
   154261 ttgctgggcg gtgagctgca cctcgccctt gataatgatc accttggcga tctccgccgc
   154321 gtccagggtg ccgaagacct ccttcagctt gtcctcggaa gccctggtgc ctttatgggc
   154381 gttcttgaag atctcgtcga tgaccatata gtctatcagc tcgacctcct ttccctcctt
   154441 gaggtggttg acgaccttgg ggtcgatcag aacctcaaag gtctcgccgt gggattccag
   154501 gcgggccacg atcgcctcat ccaggtcgac catctaaaac cccgattact cctggttgac
   154561 cttggcgatg aaggtttcca cctcagaatc gtcgaggcgg cggaagttct ccccatggcg
   154621 gaccactccg atctccacgg ccttggggtt gagcttctct tcctcggtgg ccttcttgag
   154681 ggccttgaga cccagggtga ccgcgtcctc catggacatg ccttcctggt agtcctcctc
   154741 gaagacctcc atcacgacgt tcctaccggc acctatgctt cccgccttgt aggaaacgag
   154801 agcgccgctg gggtcggttt cgaacaggtg ctcgccctgg tcgtccaccc cggccacgag
   154861 caacgcggtg ccgaaaggcc tcacgccgcc gtactgggtg tagttctgct tgtagtcgca
   154921 gattctcttc actaggtcct ccaccccggc cctctcatca taggttatct tgtttatctg
   154981 ggccaggacc ctggcctggt ccacaaggat gcgcgcgtcg gcgaccaggc cggatgtggc
   155041 gcagcctatg tgatgatcga tctggaatat cttctcaatg gatttgggct ccatcaatcg
   155101 gctagctatc ctcttgtcga cgatgagcac cactccgtcc ttgaacttca ggccgacggt
   155161 ggtcgtgccc cgctttaccg cctcacgagc gtactctact tgaaagagcc ggccatcagg
   155221 agaaaaaacc gttatggccc tgtcatatgc catctgtcct ggttgcatta aatcactcca
   155281 attatcctcg attcatgcca cctaagttat gaggacgtat atatctcttg gggattatac
   155341 gaaaaaccag aaggccggtc cagtcatcct ctggtctcgg tctccgcaaa gtacttttga
   155401 cgcaaggtca acaaggttcc ggaagtgctc aaggtctcga tcatgccttg ggggtccgaa
   155461 cgttcggcca gtaacgaaac gaccttttcc ttgtcgagcg gagagcagcg taatatgccc
   155521 atccggccat cgaactgaat gaccttgggc accttgatcc ccttggggga cagggtggcg
   155581 ttgagcttgg ctagaagctg ttcatctgaa agtttgccat ccactcggaa cgctatgtag
   155641 cgtcgccggc cccttttctc cttgaccacc atccggcgcc ctcatctgct cttgaaggac
   155701 tcgacgatgc tgttgaactt gactccagtg agcaccacca agaccctcat ctcgttcttt
   155761 atgtcaccgt gcacggcaca gccccagatt atgcgggcgc gcgggtctat ccgctcgctc
   155821 accagcaggg cggccttctc cgcctcggtg accgtcaggt cctcgccgcc tatgacgcgg
   155881 accaatgcgc ccttggcctg tttcaggtcc acgtcgccga gcatcgggga ggacagggcg
   155941 tcctctatgc acatctcggc cctctgcccg tactcgctcg attctcctag cccgatcaag
   156001 gccatgccgc cgttcctcat tatggtcagc aggtcgttga agtcgatgtt gatcagtccc
   156061 ggcttggtga gagcatcggt gatccccttt atgctctgca tgagcacctc atcggtcacc
   156121 cggaacgccg cctcaagagg tagcttgggg accagttcca gcaaccggtc gttctgcagt
   156181 acgatggtcg tgtcgcactt ctccttgagg tgttccagtc ccttgatggc gttggccatg
   156241 cgcaccgcgc cctcggcctt gaacggaagg gtgaccactc cgatggtcaa agctccagcc
   156301 ctcttggcca gatcggccac gaccggtgcg gaaccagtgc cggtgccgcc gcccatcccc
   156361 gccaccacga atacgatgtt ctgtccgtct acatatttcc agaggtcgtt ctccgattcc
   156421 tcggcggcct tctgacccac ctccggtagc gacccggaac ccaatccctt ggtcatgctc
   156481 cggcccatca ggatcttgtg gtgggcctgg atggacagca ggtgcctggc gtcggtgtta
   156541 caggccacca attttacccc atccacgcct gcctggtaca ttcgtcggac ggtattcgag
   156601 ccgcctcctc cgcatccgat gatggcgatc ttgatcttca gcgactcgac caatgcccgc
   156661 agctcatcat cgtcagcgct ggaagatatc atcggctgct cggcctcttt ttggaacata
   156721 tcatcgaaca aaggggaaat ggcacccacc tgccttatga atattctata aagtataaaa
   156781 aggcaaggaa gaccagcgtg agccgctcag atcctttaca cggtctcgaa aacggtcccg
   156841 cagcttgagc atcgatcgtc ctcgggggtc aggcgtaccc cgcactccgg gcagatctca
   156901 cctaggaacg tgccgcattc gcacttacct cgattggcat cgaactcccg tccgcagaac
   156961 gggcagatca ccaggcgaat gtcctcgaac cgctcatgac agtacgggca ctcgttctcc
   157021 ccttctcgga tctgcgttcc gcacaccggg caatagaaca tgccatcctc gtccgagatt
   157081 atcgccccgc actcacaggt tcccgagtcc ttgtagacca tcctctcgca catcgggcac
   157141 ttgatgcact ccatctccgg gtagatggcg atctgctcga cctgctccgg cgtgtaggtg
   157201 cgttggcagt aggggcagaa ctcggtcctt ttcaagcagg ttatatgaaa gatcttgccg
   157261 caatcgcatt ttacgtgcgg aaggccgtgc ttaagcttgc ccatgcagat ctggcagatc
   157321 agtccttctc ctctcaccgg acggatcttg acccgtggct ccggcgggct caacggatcg
   157381 atcctatcct catggaaggt ccagcccttg cctccgttcc ggcctcgcct tgttatgatg
   157441 tagtatatag gggtcaagct cgacaacccc agcgaaccga ggaacagggt gagcagcacc
   157501 ttgggcctga ccacctttcc taataaatca gttgccccct gattattgaa atccgtcatg
   157561 gac
//
LOCUS       DAOPZI010000002       102705 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_108_length_102705_cov_8.950648, whole genome shotgun sequence.
ACCESSION   DAOPZI010000002 DAOPZI010000000
VERSION     DAOPZI010000002.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 102705)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 102705)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..102705
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_108_length_102705_cov_8.950648"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..695
                     /locus_tag="PKM11_00985"
     CDS             <1..695
                     /locus_tag="PKM11_00985"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47118.1"
                     /translation="FCTSRKLSKDVAKDLDLDRVVELILEAHRKGELKAVALTSAVVG
                     SIRETIDRMTYVVDKVRQALPDVPIGVEPYVESFEDIDRLRNAGANEIKINIESFDPR
                     IIAIACPKLELEKQLEFLRYAVQVFGRGKVTSNIIIGLGETDRNVLEGVSTLASLGVV
                     PSIRALKINPMNRVVMEAALGKLNPVTPERLLHLNQEAKLILMAHGLSTTSYHTMCHE
                     CGCCDIVPFRDL"
     gene            781..1476
                     /locus_tag="PKM11_00990"
     CDS             781..1476
                     /locus_tag="PKM11_00990"
                     /inference="COORDINATES: protein motif:HMM:NF015956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HNX47119.1"
                     /translation="MVSENIEEYLECIWELTQDGTPARTTDIAKKMKVSPASVTEMMQ
                     RLDSLGYIVYEKYKGVTLTDSGNKIGETIKRKHRLLERFLVDVLGIANDKSHEEACRL
                     EHMLSDESERRISKMMNNPTTCPDGDPIPALDQLCLNKDEDSSVLSELSEGDEGIISH
                     LSCDDPQKIRRVIAMGFVPERCITVEEKLPLGGPVLVQVGDCRVALAKEYSDLVFVNT
                     RRHCQKRHRHGGK"
     gene            1476..3383
                     /gene="feoB"
                     /locus_tag="PKM11_00995"
     CDS             1476..3383
                     /gene="feoB"
                     /locus_tag="PKM11_00995"
                     /inference="COORDINATES: protein motif:HMM:TIGR00437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HNX47120.1"
                     /translation="MEVLLIGNPNVGKSVVFNRLTGVGAISSNYSGTTVDFLKADMLV
                     HGKKMTFIDLPGIYSLTNGTEDQMVAAKMLHSASPDCVLVIADATRLEPSLVLIFQLI
                     ELGYPILVAMNMMDTARKRGELDVAKLSKILDVPIVPTVAVTGEGMEELLKALDTCAA
                     RRSNFKVSYDSHIEAYLEVMKLSIAKAEVKYPARGASIKLLEGDEEFTEGVPKDLPIQ
                     VRKLREEFRKEHDEDLEVHVNRDRYGEAGRIISEVSRPNVQPRTRGQKLSDLTMRPRT
                     GIPILLAVLAGVLMTIIFLGSWLEGTLLSLYSDLVGTFFTDLADSIGGELGQALASGL
                     DLSIQAILAIVIPYILLFYLILALLEDSGYLPRVVVLLDGVMHKIGLHGQAIIPMLVG
                     MGCSVPAILATRVIESRRERLILGTIIVMAIPCSAQMAVIIGTVGNYGGIVYVLAILA
                     ILLGLVLILGRLLHKAIKFEPTSLMIEIPDLSVPRGNNILRKTWVRIKEFFVIAFPIL
                     LIGSIALELLNAYGILDQLVEPLAFFTEGWLGLPAIIIIALIFGVLRKEMSYQLLIVL
                     FGTANLATVMTVEQLFVFALVMATFMPCMSAFAVMLKEYGLKDTLLMAASSIVLAFTL
                     GGLANFLFQVF"
     gene            3420..4034
                     /locus_tag="PKM11_01000"
     CDS             3420..4034
                     /locus_tag="PKM11_01000"
                     /inference="COORDINATES: protein motif:HMM:NF013933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HNX47121.1"
                     /translation="MYRLFLAALALSLIFCATPGAVNTQALRVGVTGGFRRAFGVEMG
                     SIVGDMSWAVLALAGLAVIWDNDIARIVLAIVGSAFLIYLAYQGFQDARSKEIQEVNA
                     PKGHTDFVTGVIMSFANPFQIPFWIGIGSSSIAVIMSDPGLMDFVMFYFGYLVGAVIW
                     GTAYSALIGHGKRYITPTLFRILSVICAAVLLYFAVNLLYSTFL"
     gene            complement(4031..5713)
                     /locus_tag="PKM11_01005"
     CDS             complement(4031..5713)
                     /locus_tag="PKM11_01005"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HNX47122.1"
                     /translation="MSEDLEATIRKYALQNAVLYSGKANPKAVQGKVLAESPEMRTRV
                     KEVLPLIAAIVEEVNALAPEVQHKMLEDIDVTMLKREKTERRVGLPELPDMERGKVVM
                     RFAPGPSGPLHLGHTRVAILNDDYCRNYDGKFINRMEDTNPDKIDPNAYDMIPEDLDW
                     LGVKVHQTVVQSDRFEIYYDVARKLIEMGKAYVCTCPVEEWRALKEKCQPCPHHDEDI
                     ATTMDKFEKMLAGDYEEEKAVFVVKTDLKHPNPAIRDFVGLRIVKSTLHPLKGDKYCV
                     YPMMNFSVAIDDHFLGLTHVLRGKDHLNNTQRQAYLFDYFGWKVPHYTHYGLVSVPDA
                     ILKTSTVGKGIKSGEYSGWDDVRLGTVRALAKRGFRPEAIRNYWVDCGIKETDVEFSW
                     DNIYAYNKALVDKTANRYFFVWDPVPLQICGVNELHSHAPRHPDHPELGIREYQLNSP
                     IIVHVVEKDLNTAMEVGKVRLKDLGNVEFRSGKALYLGNDLSILKEGCRIIHWVPDNC
                     TPATVIMPTGERKDGFVENIPKEEEGKVVQFERFGFVKVEKVAPKLLAYFTH"
     gene            5799..7073
                     /locus_tag="PKM11_01010"
     CDS             5799..7073
                     /locus_tag="PKM11_01010"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HNX47123.1"
                     /translation="MAVQSHLDRMKGVKVIEKKVPIEIEPTRILMADQRSPVLFNDLN
                     GMKAAGNLWSERERITEALGLPKDGLTQALMQALANPRPVEEVKKAKFEEIVEEKFDL
                     RKLPIPKYYPQDGGQYVTAGVAIAEFNGKINVSFHRLMVIGKDKFAIRLVPRHLFTMH
                     KLAMEKGEDLKVAFVVGTCPSVLLAGATSADYEFNELEMASALRYIGLKEGLKVRRTK
                     YGIPVPADADYVLEGRLTSETADEGPFVDITGTYDTVRKQPVFVVDRLYRRKDAVFQL
                     VLSGGIEHFLLMGLPREPVIFRTVRQAVPRVHAVRLTEGSCCWLHGVVSITKNKEGDA
                     MNAALAAFTGHPSMKQVIIVDKDVDIFDDKAVEWAVATRFQASRGLLVINNAAGSSLD
                     PSTEGTTSKIAIDATMPIGDVKLFEKAALDKK"
     gene            7211..7894
                     /locus_tag="PKM11_01015"
     CDS             7211..7894
                     /locus_tag="PKM11_01015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47124.1"
                     /translation="MRCNNCGLDYIADNAAACPRCNAPLQMGYQQPPQQYQQPPQQQG
                     YQEQPPQQYQQPPQQYGDQQYQQQPQGAQQPPQGGYYAPPQGGYYQQPPMPPKRVPTV
                     KRVDLTEILMVVSGLFLFVGAFGNFRQVATLSQINVDIPAGIVILGIVCLVGALLLFV
                     DVLMPALLKQLGEIKDILVLVLALVFIIWGLITVFADTSKYGIYGPDIFTGGFALLAA
                     GALRMGVLK"
     gene            8005..8166
                     /locus_tag="PKM11_01020"
     CDS             8005..8166
                     /locus_tag="PKM11_01020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47125.1"
                     /translation="MATSSFERPFKIQDDDAAKAMLDAMDNPTADDHIHKSNFEADLR
                     RGLELLKKL"
     gene            complement(8330..9619)
                     /locus_tag="PKM11_01025"
     CDS             complement(8330..9619)
                     /locus_tag="PKM11_01025"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HNX47126.1"
                     /translation="MPSIAVIGAQWGDEGKGKITDYEAGRADMVVRYQGGSNAGHTIK
                     VGEEVFALHILPSGIVRNNVINVIGNGVIVDLLSLDREVAEVESRGRSVAGLKISDRA
                     NVILNWHRLLDGAEERLRGKKTVGTTGKGIGPCYSDKIARSGIRMGDLLDPELLQERL
                     DTVMPMKLKVMEILGVRLAQNQEELFKDLLAYGRKYESFITDTSVLVNDALDQGKNVL
                     FEGAQGTMLDIDHGTYPFVTSSNCVAGAICTGSGVGPKRVDEIMGVLKAYTTRVGAGP
                     FPTELKDATGDMLMNVGGEFGTTTGRPRRCGWLDLLVVEHAARLNGLTQFAVTKLDVM
                     NDMKKVKVAVAYEIDGKKVHHFPGNFKMLERAKPVYEELDGWKGWKPEETKEIVRGGY
                     EALPKEMRDYIGYIEKRSKVPAKIISIGKGREDTIRR"
     gene            complement(9665..10750)
                     /locus_tag="PKM11_01030"
     CDS             complement(9665..10750)
                     /locus_tag="PKM11_01030"
                     /inference="COORDINATES: protein motif:HMM:NF014103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine(26)-N(2))-dimethyltransferase"
                     /protein_id="HNX47127.1"
                     /translation="MNLEGNIIKEGSTQLFVPEAISERGPGKIEGRVFFNRQMAFNRD
                     VSVALFHSVIRPRKCLDAMAATGARGIRICNEAPGNHRFVINDKDALACDHIQRNIEL
                     NSLENAEVCNADLRCLLAEEKFDYIDLDPFGTPIPFVPSALQGMSRKGILALTATDTA
                     SLSGTHPGKCRRRYMANSQRNPFLHESGLRIMIGTIVRMAAQEDKGVTPLLCYYADHY
                     FRLFLRTKDGAGAADTSLAQLGMMSYDRESGERKVGEGKIGPLWLGPLMDHEEISNAI
                     VPEGLECQERVRQHFDIWKEELDVPYYYETNELAAMLKLSPPGRDELLEAMRSIGKVS
                     RTNFSPTGFRTDRPLEEVLEAFRSIGR"
     gene            complement(10747..11289)
                     /locus_tag="PKM11_01035"
     CDS             complement(10747..11289)
                     /locus_tag="PKM11_01035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTPase"
                     /protein_id="HNX47128.1"
                     /translation="MNNIKIGITGLPSAGKTNTLIQVIKMLEEDGLIVGGMITEPILD
                     DKKRNGLYVMDWMTKKRGVLAATDIHSKFMVGKMGVDLEVLQEIGVQALVNACESADV
                     IVIDEVGKIEVESDKFRDAVKEALKKEKPMLLTLHKKSRNPLLQDIRRRDDVRILEVT
                     PINRNLLPYKIMKLMKGELL"
     gene            complement(11431..11817)
                     /locus_tag="PKM11_01040"
     CDS             complement(11431..11817)
                     /locus_tag="PKM11_01040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase family protein"
                     /protein_id="HNX47129.1"
                     /translation="MTSKREELAANYFNCSEQERAVFEAGIKLGTIYHQFVGTPVAAA
                     NVEILEKAIEDGVRVQPFVKDVKVHISRDALRRKKDEFDYQTLTGIMLNVELTINVGG
                     TTVVAAMDFKEDLRYPLMYVRSVESR"
     gene            11965..12447
                     /locus_tag="PKM11_01045"
     CDS             11965..12447
                     /locus_tag="PKM11_01045"
                     /inference="COORDINATES: protein motif:HMM:NF015648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HNX47130.1"
                     /translation="MDNEPKESIDPRARKVWMIGGALGSIVIIALAVGFYFLATIGFE
                     APQWVGWTAIALALIYVPWGVYFHPWLRIRFWRYELRANELEIQHGIFVIKRHLIPMV
                     RVQYVDTEHGPLMRYFGLTTLSISTAATKFAIPALPKQRAEELRGEIATLARVSEEDV
                     "
     gene            12440..13867
                     /locus_tag="PKM11_01050"
     CDS             12440..13867
                     /locus_tag="PKM11_01050"
                     /inference="COORDINATES: protein motif:HMM:NF015648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HNX47131.1"
                     /translation="MSEFRRQHPLLILLDTGRGIISNLSFALIIAISLPDDIFGGFIG
                     NAVVALLAMFGLSALFNVLRWYFFVYSYEEGMVHIRQGVLFKRERTIKRDRVQSMNTN
                     ANVLQQAFGLVTLQIKTAGVNVDAEVNLRAVSKGEAEIIKERLYSKSARSESEPVEVP
                     RAFRFLQGRDIWLAALTSGRFMVLFSVIAVIYAQTFEYIPESYWEWAVESLSAIPLMA
                     GIGIVLGLFFLTWALSAVAFVIQFANFSVRRFEDRLEITWGVLKKNHVVVKLHRVQAV
                     VVQQGPLRQPFGLCTMLIEVAGGGAKEQERISLLHPLVRRREVEAFLADILPEYHLPL
                     VTLALPKRALRRYLFRSIVPVAVLIAMVITAFHFWELPYSWVSLILLVPAVLLGFSRY
                     RNGSISVEEDQLSLRFRYFSRVQVLIKRSHVQSMTLKANPFQRMAKLRTVQSYFLSSP
                     AGKSYHTRDLDAKDAQTVWEWYSRN"
     gene            13957..14568
                     /locus_tag="PKM11_01055"
     CDS             13957..14568
                     /locus_tag="PKM11_01055"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF014796.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HNX47132.1"
                     /translation="MEQAKRYELPKLAYGYKDLAPFLSEEQLTVHHTKHHAAYVNAAN
                     AILDKMDKARAENADLDMKGMLKDLSFQIGGHYLHSVYWETLCPVGKGGEPKGKLKAE
                     LEKEFGSIERFKKEFTAAAASAEGSGWAVLVYCMGLKKPIIMQVEKHNVNVIPGFRVL
                     MSLDVWEHAYYIDYKNLRPKYIEAFWNQVNWDAVSKKLDAILG"
     gene            14711..15619
                     /gene="nadA"
                     /locus_tag="PKM11_01060"
     CDS             14711..15619
                     /gene="nadA"
                     /locus_tag="PKM11_01060"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HNX47133.1"
                     /translation="MNAAERIQELKAQRKAVILAHNYQSPEVQDVADYVGDSLGLSQK
                     AASTDAEVIIFCGVDFMAESAKILSPNKKVILPESDAMCPMSAMCTDLELAPVKEKYP
                     EAAIVAYVNTSAAVKALADVCCTSANAVKVVGKMPQKRIIFVPDRNLGAYVQRFHPDK
                     EILLWPGFCPTHHDMDVQDLKELKKKHPKAKLMVHPECTPEVIDLADNVSSTEGMIKY
                     AKGSDAQEFIVGTEVDMTYRLGKEVPGKTFIPVPTAVCPNMKRTTISSLIKALETLSP
                     EITLAPEIIEAARKPLERMMEIGRGD"
     gene            complement(15633..16253)
                     /locus_tag="PKM11_01065"
     CDS             complement(15633..16253)
                     /locus_tag="PKM11_01065"
                     /inference="COORDINATES: protein motif:HMM:NF013933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HNX47134.1"
                     /translation="MDSALLFLGSVAIISLSGVLMPGPVFAVTIACGFQDRWSGWKIA
                     LGHSLVEVPTIAAIFFGLSVFLKNDMVLAAIGLLGGAILLYMGYDVVRTRKEVVTSCP
                     TKHQDPFWAGVTTTAFNPGWLLWWATVGAALTATAVTFGWWMLPFFVVVHITCDLLWE
                     GFVGMTIFGTKGKWSASWHQRVIAGSGVLMVVFAILFVFDALQTLL"
     gene            complement(16263..16898)
                     /locus_tag="PKM11_01070"
     CDS             complement(16263..16898)
                     /locus_tag="PKM11_01070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47135.1"
                     /translation="MDKFAQDLESLIDKLVAGCDPHCEESLRNLYQRLLDLKEKNLLK
                     INHSVLEMVVAKYLIEDGYEVDLEHMIDAGLSCDVYAEKDGNIMIVEVETGYVPPAHA
                     LDPMDYIRARIASKIARYSNHCQKFMLAAPPHYVMPVMPFFTLPTRDRDEKEAWVVKH
                     YCDLYYKSPPVSMNEIMNSHIHSVSIIEVESGTLRNLPPEVYINLTVDWYL"
     gene            complement(17086..17229)
                     /locus_tag="PKM11_01075"
     CDS             complement(17086..17229)
                     /locus_tag="PKM11_01075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47136.1"
                     /translation="MEDAKTSFVGVPYSLRVAHEITSEGYGFCVSCETGTITDVFSPS
                     AED"
     gene            complement(17490..18005)
                     /locus_tag="PKM11_01080"
     CDS             complement(17490..18005)
                     /locus_tag="PKM11_01080"
                     /inference="COORDINATES: protein motif:HMM:NF017663.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HNX47137.1"
                     /translation="MHVNDHEADAEEHEAGPVDFMTDEELDPDVIVFFVAGEPVPQGS
                     TKAFYIKKLERVVTTHTNANTEAWRHRIATEAQHANQLRPQSYFSEDRRLGYEVLMEF
                     VFTRPKSTPKRWKMNTKRPDLDKLVRAVLDGITNVLIPDDSQVVRITASKCYGECDRS
                     PGLHITIRRLD"
     gene            complement(18061..19365)
                     /gene="aspS"
                     /locus_tag="PKM11_01085"
     CDS             complement(18061..19365)
                     /gene="aspS"
                     /locus_tag="PKM11_01085"
                     /EC_number="6.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004815 - aspartate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006422 - aspartyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA(Asn) ligase"
                     /protein_id="HNX47138.1"
                     /translation="MLHDSRSITANEYDKEVTVEGWAQEIRNLGGISFLILRDRHGVV
                     QITAPKKKIAPEVMQTITSLARESVVRVTGTVKQSAQVKAGYEIIPSSLIVTGVAQTP
                     LPMGVVDKVDVEMETRFNHRYMDLRKPEVRAVFEIKSLTMRLIDEYLADNDFIEIFTP
                     KLVASGAEGGSTLFKVDYFGKQAYLAQSPQLYKQMLMSTGLDRVFEIGPAFRAEPSDT
                     ARHVSEFVSFDGEMAHIDSQSDVMAMIEGCTQFVISEVKERGKWALEVLGVDVVVPKA
                     PYPVISYEKAIGMVQGAGFKIELGEDLGTEGEKLLGDLMAQDGYEMYWIAEYPEAAKP
                     FYIMEKDGTPYSYSFDLDYKGQEISSGGQREHRYDRLVQRMEKMGLDPKSFEFYLNAF
                     AYGMPSHGGWGLGVERMVQKMLGLNNIRETILFPRDRNRLVP"
     gene            19497..19721
                     /locus_tag="PKM11_01090"
     CDS             19497..19721
                     /locus_tag="PKM11_01090"
                     /inference="COORDINATES: protein motif:HMM:NF024851.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HNX47139.1"
                     /translation="MPVEVRIDQNACTGCGICYNDECPDFFMEGDDGNSNVKPLYQKG
                     DRSIGEAPDSLINCVKNAEASCPASAISVK"
     gene            19835..20977
                     /locus_tag="PKM11_01095"
     CDS             19835..20977
                     /locus_tag="PKM11_01095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HNX47140.1"
                     /translation="MSQKVTVSVIKADVGSVAGHSKPHPKMMRKCEEVLVQGVKSGVI
                     NDFYVTRVGDDINLFMTHFKGENHKDVHGLAWEAFQEAAKLAKEMKMYAAGQDILSDA
                     FSGNIRGMGPGAAEVEFVERGAEPMVFFMADKTEPSAYSMPLSRIFMDPFTTTGLVID
                     PRAHEGFRFEIVDVMDSKKIVMSAPEETYDILSLIGDTTRYAIKRVMSKDKNLGTACV
                     VSTEKLNICAGKYVGKDDPVAVVRCQSGLPAVGEVLQPFMFPALVAGWMRGSHYGALY
                     PCSVEDSDPTYFDGPPRICALGFQISNGRFQGCEDPDAPLGKKIPVDYFSGSVWDEAR
                     RKAVRASIYMRQHGPFMPSILGPEEMEYTTRPAVLGKLKDRMEKID"
     gene            20970..21647
                     /gene="tpiA"
                     /locus_tag="PKM11_01100"
     CDS             20970..21647
                     /gene="tpiA"
                     /locus_tag="PKM11_01100"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HNX47141.1"
                     /translation="MTDLRTPVIIVNFKVYSEVEGPGAVRLAKDCESVALVKKANIVV
                     CPPMVELSKVASAVTIPVFSQHVDNRSPGSITGFVSPQSVRSAGAAGTLINHAEHRMP
                     PQDIVAAIDSCRKLGLISVVCTDTAETSAAMAAFSPDFIAVEPPELIGGDISVTTADP
                     TIVSRTVEMVKAVDPKVKVLCGAGVKNGKDVRAALDLGASGVLLASGVVKAKDVKAAL
                     QDLVSAL"
     gene            21755..23647
                     /locus_tag="PKM11_01105"
     CDS             21755..23647
                     /locus_tag="PKM11_01105"
                     /inference="COORDINATES: protein motif:HMM:NF024491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="HNX47142.1"
                     /translation="MPVQASDAESSDGLLISRVCASYPGEFISLTNHGPSLDVLGWRI
                     SDGEGSVTFSRSLIITTGGSVTWSAPGSFFPELYAEEDCFSNDGASVILKGSLKLADA
                     GDQVYLFDAGGALRDMVCFGNVEPNPPWTGPPAVLKKGSVIVRTATGNGPGNWDMMVP
                     GLFSLSSPLFPADVVPLLYPDDALPELVRQIDISHESIQLACYLMENWTLARHLAGAS
                     ARGLNVTVLLEGRPVGGVSENGAALAYYLQDSGVNVWTMRSGESFRRYDYLHAKYAIF
                     DRERLFVASENMADSSFNSNRGWAAVIMGSQISSFAEDVFLKDISAKGVDIFPLSATL
                     VRADGGPGRLLSTVPAPPREYSAMVSLVTSPFNIQDRLVEMISAAQERVLVQQMRIDE
                     DWIDDSKIMSVLSGAAERGVSVRIHLDAGLGTEKGNKMVAEALNRKAKDNDWDLECHL
                     TDEISSFGRLHNKGVIVDDTVVVGSANWVDGSMQRNREMAVVLRSADLANVFVQWFQD
                     DWKGDAIPPTVVLPWHYLEANAGEPVVLDATGCYDPSGIANITWDVDGDGSADLFGPM
                     HAVTLREGSYNITLRLEDALGNVALDNVTVLVNPSSDGTVTWLLYAPLPLLLAVILFK
                     RRTRRL"
     gene            23672..24106
                     /locus_tag="PKM11_01110"
     CDS             23672..24106
                     /locus_tag="PKM11_01110"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47143.1"
                     /translation="MQIRHFQNRDLADVWQVASESLRERYDPTIFTQLVPFWPDGFLV
                     IEDLGRVIAFVFGVMTGVQHARVLMLAVNSNYRGAGLGTLLTQEFFRECAKKGVRQVS
                     LEVRASNLAAQRFYLRLGFFNVRRVSKYYSDGEDGILLLRYL"
     gene            complement(24103..25614)
                     /locus_tag="PKM11_01115"
     CDS             complement(24103..25614)
                     /locus_tag="PKM11_01115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX47144.1"
                     /translation="MSGADRVSWRSFESTAQVSIPSDPLLRVIGQEEAVTLARIAAKQ
                     RRHLLLVGPPGTGKSMIAQALALHLSRPTQEIRVVHNPENPERPLVEVKNENEVGSES
                     KTKEFAEGELIEPKNAPVNVAERLGYRCRNCGAYSSPKERVCPKCQKNKGADVAANNP
                     FGDLMSGLFEQMNAAGLTGTAGKERVTTTRTRFGKEEVVVFERCGEMIRLLDQDALEK
                     RRDWEKQSPRKVLVRLDRNPFVLATGSSETELLGDVRHDPYGGHAQLGTQPYDRVVPG
                     AIHEAHEGVLFIDELPHLGHLQRFILTAMQERRFPISGRNPQSSGASVKVDNVPCSFI
                     FVGACNIQDLEQVLSPLRSRICGNGYEVLVNTAMPDTEENRDRLVQFIAQEIVSDTRI
                     PHADASAIEAIMKEARARAAKVDNINNALTLRLRELGGLIRAAGDLAVGENAELITAK
                     HIAGAVERSKSAEEQIKDRYGSYTKGLGTDISSAQKEKSPYYFWNQTKDSMFH"
     gene            complement(25617..27158)
                     /gene="dnaG"
                     /locus_tag="PKM11_01120"
     CDS             complement(25617..27158)
                     /gene="dnaG"
                     /locus_tag="PKM11_01120"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase DnaG"
                     /protein_id="HNX47145.1"
                     /translation="MNIDPSTTKYLVKAKLNADGIVEKPDVVGAIFGQTEGLLGDELD
                     LRDLQKSGRIGRIEVDVHSRQGKSEGQILIPSSLDQVETVILASALETIDRVGPCKAK
                     ITVESIEDVRVVKREKIIERARELLTELIKQSKTSGIDLTESVRQSVQVEEITYYGKD
                     RLPAGPNVAESDAIIVVEGRSDVLNLLKSGIKNAIAVEGTNVPKTIMDLSKERVITAF
                     VDGDRGGELILREMFQVAEVDFVARAPRAHEVEELTQKQIMKCLRNKIPGDQFIEMFN
                     LDLGDAKDKEKRLEPNNVKVEKLERFEKAERADRDKEKDDEPVRTEREPRAEKPERRE
                     REEPRQEKEPRPEPRPERQERREREPRAERQDRREREEPRQEKEPKAEQRQEREPRAD
                     RQERPPVEEKELEERKPVSRKQLSGAQEKFKGMINELSSTSKARILDAMGGIKKEVAV
                     KELVNTLKEEKDPVFAVVFDGIITQRILDLASDLKIGTIVGTKMGNITKQPAGTDVWS
                     KDDLN"
     gene            complement(27433..27642)
                     /locus_tag="PKM11_01125"
     CDS             complement(27433..27642)
                     /locus_tag="PKM11_01125"
                     /inference="COORDINATES: protein motif:HMM:NF014636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoaD/ThiS family protein"
                     /protein_id="HNX47146.1"
                     /translation="MSDVVLTVEVDRKAKEIRLPEGSTVQAMLDSLGLYPDAHIVVRG
                     RTPVPVDSPLLDGDQLRIIKVASGG"
     gene            27745..27851
                     /locus_tag="PKM11_01130"
     tRNA            join(27745..27782,27804..27851)
                     /locus_tag="PKM11_01130"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27779..27781,aa:Ser,seq:cga)
     gene            complement(27856..28410)
                     /locus_tag="PKM11_01135"
     CDS             complement(27856..28410)
                     /locus_tag="PKM11_01135"
                     /inference="COORDINATES: protein motif:HMM:NF013936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HNX47147.1"
                     /translation="MRISVTLLQYDHGIVRQVLDVVGELMRSHRADRHPVEFREALAF
                     LEQFLDRFHHAKEERFLFKAAAVECPKVAETLSRLKKEHAQARRMMRNALKALDEGDL
                     PKAEKEARKLVEHMTLHISEEENLVFPHIENCLQLETDAKVHLQYERFMEKEFGKDYY
                     QVAEAFANDIQERLLGPGFFKGIV"
     gene            complement(28452..29237)
                     /gene="larE"
                     /locus_tag="PKM11_01140"
     CDS             complement(28452..29237)
                     /gene="larE"
                     /locus_tag="PKM11_01140"
                     /inference="COORDINATES: protein motif:HMM:TIGR00268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HNX47148.1"
                     /translation="MEMEAAKKKYQGLVGSIRSMERVAVAFSGGADSTLLLKAALDSG
                     AEVTAFMAIGEIFFPQEQSGAIHLAEKLGVDVVTLKIDLVNDGQFARNWEDRCYVCKS
                     AIFSRIKKEARELEISHILEGSHLDDLKEVRPGRAALMDLNVRSPLIDAQLTKAEVRA
                     LLKDLGLPNWDLPSNTCLATRVPHDVRITSTILRRVERAEAALAPFKFKNLRVRDHEY
                     WARIEVAPEDVPRLFQEREKVVQALKKLGYRKVALDLEGYGAR"
     gene            29341..29622
                     /locus_tag="PKM11_01145"
     CDS             29341..29622
                     /locus_tag="PKM11_01145"
                     /inference="COORDINATES: protein motif:HMM:NF014101.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF134 domain-containing protein"
                     /protein_id="HNX47149.1"
                     /translation="MKPRVLRGPSNYSSFRPSSETTSEPIVIYPDEVEALRLVDHLGL
                     NQEEAAKSMGVSRGTVWRCVDSGRKKLISMIIEGRPLQVANVDESCDNC"
     gene            29701..29958
                     /locus_tag="PKM11_01150"
     CDS             29701..29958
                     /locus_tag="PKM11_01150"
                     /inference="COORDINATES: protein motif:HMM:NF036294.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5320 domain-containing protein"
                     /protein_id="HNX47150.1"
                     /translation="MPYRDGAGPQGTGPNGRGMGPCRSGGRVAFGMGRDRRMGHGRGF
                     RFMSECSEADLNTNLEAKVEALEARLKYLKAQLAGEGKGSP"
     gene            29955..30278
                     /locus_tag="PKM11_01155"
     CDS             29955..30278
                     /locus_tag="PKM11_01155"
                     /inference="COORDINATES: protein motif:HMM:NF014620.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HNX47151.1"
                     /translation="MKVAVTSSGPGTEDLMDDRLGRCPYFVIMDTSSGSIESFANPAI
                     DASSGAGTKAMQALIDKGVEVVITGRIGPHAQAMLEETDLKGVTGRSGIVGQVLKDYL
                     ADSKS"
     gene            complement(30296..31192)
                     /locus_tag="PKM11_01160"
     CDS             complement(30296..31192)
                     /locus_tag="PKM11_01160"
                     /inference="COORDINATES: protein motif:HMM:NF022077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX47152.1"
                     /translation="MIKIAVLSGKGGTGKTTAVASMSWYSEDLVLADCDVDAANLALT
                     MHGRPRTKDDYLGAYTAAIDLDLCTECGRCEDNCHFEAINDLKVNAIHCEGCGACQVV
                     CPAGAVSMSLRKSGEIFVLDTARGPMVYADLFPGESNSGKLVTIVRRLADDLAGSDGI
                     DTVLIDGPPGTGCPAIASVSGVDLILAITEPSRSGEHDLMRLIELAHHFSIPICVAVN
                     KWDLHPGMTCEIEESCRRQGVVIVGRIPYDPNVLESVKAMQPLPSMFPDSPAALEYQR
                     IWKEVRSRSKDRRGSGIALKLD"
     gene            complement(31189..32019)
                     /locus_tag="PKM11_01165"
     CDS             complement(31189..32019)
                     /locus_tag="PKM11_01165"
                     /inference="COORDINATES: protein motif:HMM:NF013793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX47153.1"
                     /translation="MIVAVASGKGGTGKTSVACALGLALDRPLTFLDCDVEGANAHIF
                     LHPYLRSEEEVVIPYPTIDRSKCDACGICVSKCHFGAMVRLGKKVKVMESLCHGCGVC
                     RLVCPQDAVIMSGRPVGTVHIGTAGLMRFFCGELRTGEALSVPIIKRLKKEMDDTVII
                     DCPPGTSCPAVEAVEGSDFALLVTEPTPFGIHDLKGMIEVCRRLDVPCGVIINRSFGE
                     DREVESLCKTEMVPVLLKVPFDRKVAEIYARGGTLLEAMPKLTDKLNDVFIEIVGLKR
                     "
     gene            complement(32029..32388)
                     /locus_tag="PKM11_01170"
     CDS             complement(32029..32388)
                     /locus_tag="PKM11_01170"
                     /inference="COORDINATES: protein motif:HMM:NF014620.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HNX47154.1"
                     /translation="MKVSIPVMDRSGLSSTVGQHFGKVPDYAVMDTESGTLSFLENTS
                     EHRGGVGMPPELLAKAGVQVMLCSGLGPKAVDMLSSLGIQVFVGAKGTVGETLEAYNA
                     GKMIRADHDNACKEHDH"
     gene            complement(32534..32749)
                     /locus_tag="PKM11_01175"
     CDS             complement(32534..32749)
                     /locus_tag="PKM11_01175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47155.1"
                     /translation="MVWKGREEFIKAGNKIVWAGLLLFAIGLLLTIMGGAVDLLWMYI
                     ISSLQAFGVGFILIGSAVFLVGRLKED"
     gene            32876..33643
                     /gene="larB"
                     /locus_tag="PKM11_01180"
     CDS             32876..33643
                     /gene="larB"
                     /locus_tag="PKM11_01180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HNX47156.1"
                     /translation="MNVRDVLDAYRKGDIDLQRAEQLLRMDFLERVGEHTLFDHAREA
                     RRGIPEVIWGENKSPDMVAEIVSTVLKDRDAVLISRASPEHVKALKATVNEEHVRYIE
                     RSKLIVVDRRKDRPKIGKIGILTAGSSDIAVAEEAKAMAEVMGCEVLTEYDIGVAALH
                     RFLDPLAKMLDQGVDALVVVAGMEGALPTVVSGLADVPIIGVPTSVGYGYGGKGEAAL
                     MGMLQTCSPGLVVVNIDNGIAAGATAALISLRCRRNR"
     gene            33648..34535
                     /locus_tag="PKM11_01185"
     CDS             33648..34535
                     /locus_tag="PKM11_01185"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47157.1"
                     /translation="MNIRQLRAGDVPSAQALMADTWSNLLKRQTGLDISYPVRQATWY
                     TSRLRHEPLGCICIEENGKLIATGFALSCGNVGWIGPMEVRPDKQGKGYGSQLLLSLE
                     TYLSTRGCKAVGLETMKDVSRNLDFYSQAGYAVEQDMLFLEKDWLDGQDAGRPEGSKF
                     DPKEIKRLGSTINPGFDPSVEFQVYEEMGIGRTLTAEGAVALLLTDPIPGSGKAYLRT
                     VLTEGYHRLDEAIGLVQKAEREALWSGARSMFTIIPAQSELLTSLIRGGYKPKGADVR
                     MMKGKFVRSHECSIFSWSG"
     gene            complement(34532..35356)
                     /locus_tag="PKM11_01190"
     CDS             complement(34532..35356)
                     /locus_tag="PKM11_01190"
                     /inference="COORDINATES: protein motif:HMM:NF015957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HNX47158.1"
                     /translation="MVYCPKCGAVNEDQASFCQKCGGKIVTQQPTASQPVKRAPAVWN
                     QTPFDRTFRGGGPLLKAFLGLIFVLLLMEIFKALSSESLFAERFSEFLGDTLLLFFLM
                     FLLAFYFGYYTRKYPRESSIISPLITAIIVTFVLWVVSKAFGFLGESRSDDFLTAMGD
                     MVSSVLYIIFLLIILLGYIGVIMKASKVGFPPRNVNVPPVPPAPAAPQASYAPGKRMG
                     RSSRDKIILGVCGGMAEYLETDPFLVRVLWVVGTLLTSGVLILAYIVMAIIMPENH"
     gene            35448..35822
                     /locus_tag="PKM11_01195"
     CDS             35448..35822
                     /locus_tag="PKM11_01195"
                     /inference="COORDINATES: protein motif:HMM:NF014664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HNX47159.1"
                     /translation="MAEGEEARVRRVLERAKEEYGFVPLVSEVMSDRPDLFLPYAEIS
                     SGLFFKPKHMDRKTAELAAITAGAALGSENCLGVHILQAFKIGVSEEAVLEAMILGGF
                     MSMNRSNSISFRCLKAAKESMR"
     gene            35819..36262
                     /locus_tag="PKM11_01200"
     CDS             35819..36262
                     /locus_tag="PKM11_01200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HNX47160.1"
                     /translation="MRCSVGSVGRVLVIRLEDGDILHECVERAAKENDIIRGAVLALG
                     GADRGSRMVVGPKDGRADRIEPMMAQLAGESELAAVGTLFPDENGVPSLHMHASAGRD
                     GRSVTGCVRAGVKVWLIQEVVVIEILGSDSRRAKDPRTGFHLLEP"
     gene            complement(36263..37099)
                     /locus_tag="PKM11_01205"
     CDS             complement(36263..37099)
                     /locus_tag="PKM11_01205"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47161.1"
                     /translation="MSNLDLFMMMDDGRPVPKAPRISEVRTRVALPASRLPGLDYALN
                     PYVGCQHDCLYCYAPYVTKRPRGEWTTILARTDLPQALAKEIKGKKGMIGLGTVTDPY
                     QEAERHLLITRRCLMEIVPHGLSVSVLTKSDLILRDIDLYKELKGEVGITVTSVNDEL
                     SAMLEPGAPLPGRRVDALRRLSEEGLNAYALIGPLLPLLTNVDIDEMVDALSSTGIKW
                     VMLDRFRPRPGMFDDIARRANGTEVAERLEKAHRAEDYRSLEATVRRRFSEKGIRCVN
                     AF"
     gene            complement(37086..38390)
                     /locus_tag="PKM11_01210"
     CDS             complement(37086..38390)
                     /locus_tag="PKM11_01210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nre family DNA repair protein"
                     /protein_id="HNX47162.1"
                     /translation="MVERTIMQGFAPLPLDDQTFTSAHKDSSSLCHICKGSKNLCGKD
                     RCPLMIKFYSYTKTKRLINAQDLHGSSPPGVFVGRYGYPKVDIGPLVPPDLGDTLIMD
                     TPEQWMGKSMEEIVDFRFRLVRGKHLVDVKNFQNAGRIVDFTRELALAVNSVDVEARF
                     SKKPSGRIVLDDNIQPFGPSAKLEKLSITNPKYDHRVEKAYYDTDLKAVEAVKGLYKN
                     EVLISRIQKAFSIGAFGIEQNRRLVPTRWSITAVDDMLGKDLLKSTKTFPLINEFRVY
                     DWDQLDNRWSVMLTPTSWRYELIEAWYPNTVWNPAGLQVEIISSHEFFDGRKDYAEIG
                     GCYYAARLAVNELLQRERRQSGAVIFREAHPGYLLPVGVWNVRENVRMALTQRPRKFN
                     TLDQALAYVQTRMDIPISTWTDHSAILKDLKIQRRIDDYVEP"
     gene            complement(38423..38713)
                     /locus_tag="PKM11_01215"
     CDS             complement(38423..38713)
                     /locus_tag="PKM11_01215"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47163.1"
                     /translation="MDEDLERFRVDVGYCRSCLGMQGGREQRVYRFPNGYGASLISAP
                     RLGGPERWTIMALRFDGDDYETADLPGIENGTKADMSALLKLLKVIFSQPHF"
     gene            38893..40560
                     /gene="thsB"
                     /locus_tag="PKM11_01220"
     CDS             38893..40560
                     /gene="thsB"
                     /locus_tag="PKM11_01220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thermosome subunit beta"
                     /protein_id="HNX47164.1"
                     /translation="MGQGNQPIIVLREGTDRSRNKEAQFNNIAAARAVADSVKSTLGP
                     KGMDKMLVDSMGDVVITNDGVTILKEIDVQHPAAKMVVEIAKTQDTECGDGTTSSVII
                     AGELLKKAEALVEQNIHPTIIANGYKMAAAEAIKILETIAVSVTPDDTEMLKRVSMTA
                     MTGKSVGGQGEFLSEVAVKAIKAVAEKSGKGYNVDVGNIKIEKRTGGSIAETEIIEGV
                     VIDKERVHPRMPTQVKKAKIALLSVPMEVKKTEVDAKIQIRDPSQMQMFLDEEEAVLK
                     KMVDQVAASGANVVFCQKGIDDLVQHFLAKAGIFASRRLKESDMEKIAKATGGIIVGK
                     IDNLGKSDLGLADVVEQKKVGENDMVFITGCKNPKAISVIVRGGTEHVVDEVERSLHD
                     ALRVVGVALEDGKIVPGAGAPEVELSLRLANYASTVGGREQLAIEAFASAMEVIPWAL
                     AENAGLDAIDMVIQLKSAHEKKGANSKYMGLDLNLGKPVDMLKANVIEPLRVKTQAVK
                     SAAEVANMILRIDDVIASKKSPPAPPGMDGMGGMGGMGGMGGMPGMM"
     gene            40818..42020
                     /locus_tag="PKM11_01225"
     CDS             40818..42020
                     /locus_tag="PKM11_01225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47165.1"
                     /translation="MEVDADEELQEELENVTTTVDQFLDDIEGLNANLNDLNVAASSE
                     LWVLFEVTEANDDVYVLSMDMAAMISVDASISVTAELPAEGTYDIGELMTAERDPVTM
                     SASVDLTMFLTVSVDVTFDSDTMALKSIEATLKLTGALDLTADNLPLWLPGLMDNDLN
                     ESLTGEIKVEYTDYDINADLEFNLAMNLEFVPALNLWDFPLDVGDDWNVSSNATLSGS
                     MSGSLDVSGLPSDMEDAFFEKVADKIGANSFPIVFEDLDLGDCPFDGGVMEETTEHIG
                     PVNLRCTDVSTVNDPYWNDITVYEINVVDTPLNMYYSPDVGFMSYFSMNMGEMGEEMP
                     DRDFRMDAVDPDDAEANIADVTERQGEVQEDSGALGFFTDAPYLGIILVVVIVVVVVA
                     AIFLIRKK"
     gene            42133..42597
                     /locus_tag="PKM11_01230"
     CDS             42133..42597
                     /locus_tag="PKM11_01230"
                     /inference="COORDINATES: protein motif:HMM:NF024135.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HNX47166.1"
                     /translation="MKVILVYDSVSTEKLTAKVAEVIATTLKGKGLDVTTVPVGDAKH
                     LKLEEYDALVVGTPTMAWAPTKPIKEFLKGLDVNKVKGKKAASFDTQMRSFISGNANK
                     AMESRFKELGMTVACPHLLAYVKSEKKVYHFLDGELQKAEDWAKGLADALSK"
     gene            42647..44029
                     /locus_tag="PKM11_01235"
     CDS             42647..44029
                     /locus_tag="PKM11_01235"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012398.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HNX47167.1"
                     /translation="MVVRSINPRNGQVVKEFVSNLPDDVLPRLVKGRDAQRKWIGEWD
                     LEERIEAVLELRSALLAMKDDMIATEMLEGGFPQRDVIGTYNGVIKGFEHYAAEAKAT
                     GDYEFPLDPAGWPDTKATINLVPHGVIAHIGIWNYPLWQTMITLIPALMAGNAVVFKP
                     SELTTMTGMKIQEAFNKTSMPSGLFQTLIGGPEIGKAMVAAPFDALVFTGGRATGLDI
                     TRNAGIKPMILELSGNDPGIVCSDVNVHETARGIASGAFSHGGQVCIRIKRLYVEEGV
                     ADAFIAELKKVVARIDVEEQVGPLIREEARAQVREKVQRAVQAGCELLTGGKDLPGPG
                     YYFEPTVLKVTDDSLEIIKEETFGPVLPIRVVKDVEEAIRLANQSDYGLGATVWTCDP
                     VKGEAIARRLEAGNVWINEHGRTINCGELFQGWKCSGIASTNRRITLFMKKRTIVNHQ
                     SCVARPHWFK"
     gene            44070..45029
                     /locus_tag="PKM11_01240"
     CDS             44070..45029
                     /locus_tag="PKM11_01240"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47168.1"
                     /translation="MVGNSGEMVSVRGLYKRYKDLPVLLNLSFDIPKGSIFGYIGPNG
                     SGKTTTIKIMTGLIRDFQGDVTIEGRSIRNWNTELSSTIGYLPQQTSLQEWRTVDQSL
                     HTFGRLSGLQESEVSKRIKEVTEELGITEYRKRKVNKLSGGTLQKVGMAQAMLHRPKL
                     MVLDEPVAGLDPESRVLFKNLFRQLSREGTTIFFSSHILSDIEDVADTIGILGQGRMR
                     YIGSMEELRERVGRSTEVRLETVEPLLNDSVLEIIPGITRVERVADNRFHILLREHGE
                     MDAVVDRLIKAVLAEGLHIRAIHPNRQSLESLYLSYTDQEGSP"
     gene            45026..45682
                     /locus_tag="PKM11_01245"
     CDS             45026..45682
                     /locus_tag="PKM11_01245"
                     /inference="COORDINATES: protein motif:HMM:NF024141.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47169.1"
                     /translation="MSLWLLFKDELNGFYRSKVMLALWVGLPVMALLLYFLVDDIEGI
                     PLTVFTGLLVSSIGGLLTSVLIVVNILNEKEKKVYDLFLIRPIRRENLLLAKFGAVFL
                     CVMVASFIAITLAAILDSANEGYDIGSILTSMKDSLIITVSLMAINCSAGVLIGVFSP
                     SVLVGVLLVLFGSNQLSSLVLIPMISGWGEMWMVGLASIGISALLLFGASLVFRRKEF
                     "
     gene            complement(45685..46176)
                     /locus_tag="PKM11_01250"
     CDS             complement(45685..46176)
                     /locus_tag="PKM11_01250"
                     /inference="COORDINATES: protein motif:HMM:NF021422.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2124 family protein"
                     /protein_id="HNX47170.1"
                     /translation="MRIELEGNMVKADGISGLTRLFREALVGKDDGSKVLFVGSEAVC
                     PPFAQLLAYAVRDRNMHFGFCPRAEIDRSRTMRWVDGAGFQIGTEPFRSTEADVVVIL
                     GGLAIPKFGCPVEDVKLLISQIPNHRLLIAMGFMDVFRKAGWDTALNFDVLIDAHMSA
                     EVL"
     gene            46544..47401
                     /locus_tag="PKM11_01255"
     CDS             46544..47401
                     /locus_tag="PKM11_01255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HNX47171.1"
                     /translation="MSDNVQLRAAIYARVSTEDQAREGYSIAAQLKRLRSYCLARGWT
                     VANEYVDDGFSGRSPERPEYKRMMHDKDIWDVVVVLKMDRIHRNSRNFTMMMDFLRSW
                     NKEFNSTQENFDTTTAIGRFVMDTVQRIAQLESEQIGERVKVAMVQKALEKKGHLGCP
                     EPYGYRYLEGQLLIDDSEAQVVEGIFRMASNLCSLGQIVEWLNSSHIPTKNGGEWQRS
                     TVHGILANRMYLGEMVWDGLVQEAPNLKIIDSQLFQEVQGLLAQRMKSRRTPKRIPAK
                     SLFRSEAHA"
     gene            47394..48215
                     /locus_tag="PKM11_01260"
     CDS             47394..48215
                     /locus_tag="PKM11_01260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HNX47172.1"
                     /translation="MPRAAIYTRVSTEDQAKEGYSLSAQKQRLEAYCDAQGWDVADYY
                     IDDGHSGRNTRRPAYQRMMEEREKWDIILVMKMDRIHRNSKNFMIMMENLEKWGKKFS
                     SMSESLDTSNAVGRFVVDIIQRIAQLESEQIGERTYMGMRQKAESGQGLLGFRVPYGY
                     RLREGVLHVDETEAEVVRSIYERYLSGQTMEMIAWGLNRDGITTRTEGEWTVWSIGRI
                     LHNPVYAGYLRWEDLVNPSPHVPIISVPTFNKVQIEISGKVKNKKHASVKLLPEN"
     gene            48601..49173
                     /locus_tag="PKM11_01265"
     CDS             48601..49173
                     /locus_tag="PKM11_01265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47173.1"
                     /translation="MAEESNVHIKVAGAEVLGLLLIAMIGVLIAMYGLGMFDTLSVIA
                     GVAGTIGVGMLLVTIVAYLNENILVSAAFGLVAVFLMGFVGMATPVLSGVPEANLAAE
                     YYTIFFGIGLILIGVVAFGQPIKILPIFLLIAGLSVLLLGLWFDMGEDIRMVVGVFWL
                     ITTLMALYMAAAIGMFVVKGKMVLPLLVKA"
     gene            49261..50070
                     /locus_tag="PKM11_01270"
     CDS             49261..50070
                     /locus_tag="PKM11_01270"
                     /inference="COORDINATES: protein motif:HMM:NF013761.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline dehydrogenase family protein"
                     /protein_id="HNX47174.1"
                     /translation="MTGDRARWCCEDLNEAIELAARRNKQGIRCIIDPLGELAKDDAA
                     SDKALAEAIQTIEAISTNGLHASVALKPTALGAAYDHDGCMKRARELARLAWKDGIDV
                     ELDMEARKYVDDTLHMATELMSTGNGQMSIALQAYLYRTPMDARSMNMAGVKVRLVKG
                     AYAGDLVDFNDVATAMLDNIDLLATAGRPFSIGTHDPRVIERLWKNRAFKGLIEVGML
                     KGLGDQTKVKLAGKGWSIAEYVPYGRDSFAYIARRENYVRNLSKLGLQPVP"
     gene            50688..51218
                     /locus_tag="PKM11_01275"
     CDS             50688..51218
                     /locus_tag="PKM11_01275"
                     /inference="COORDINATES: protein motif:HMM:NF012436.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HNX47175.1"
                     /translation="MKASIEKALNDQINAEIYSAYLYKSMEMYLQSIDLPGMANWMNV
                     QTQEELAHAEGMIQYINVRGGRVLLTAIEAPKKEWKSPAEVFADAYDHEANVVTVKIH
                     KLVDLAIKEKDHAFNQFLQWYVAEQVEEEDNTSTLLRKLKKVGDHTPSLMQVDAQLAA
                     RVFRAPVIPGTTVGGP"
     gene            complement(51270..51722)
                     /locus_tag="PKM11_01280"
     CDS             complement(51270..51722)
                     /locus_tag="PKM11_01280"
                     /inference="COORDINATES: protein motif:HMM:NF014522.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fasciclin domain-containing protein"
                     /protein_id="HNX47176.1"
                     /translation="MGLFDFLKKKGSWVADPNLKTIAETVVADDDYKTLVAALKEAGL
                     VDLLGKKGPFTVFVPNNSAFIDLPDGTVEALLKDKAKLKAVLTHHVVEGAFSYDQLMA
                     KPTVAAADQKELAVDAKGLLKIAGATIIRGNIKCRNGYIHVVNKVLVP"
     gene            52084..54840
                     /locus_tag="PKM11_01285"
     CDS             52084..54840
                     /locus_tag="PKM11_01285"
                     /inference="COORDINATES: protein motif:HMM:NF012271.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HNX47177.1"
                     /translation="MQINKLRASAIAWILLVPLFMGLILITDVDATPTPVLDEISWMK
                     GAIDSHSDVSNIVSQAIDGDGHIHVSYYNSDTNRLMYATNSNGVWRSQVVDSTTSAGK
                     YNSIAVDGDGVVHISYSNDANNDLKYASGNFDSWTLTTVDSATAVGDFNSIACHDKKV
                     FISYYNYSGQSLKLAVKTAGRWSTTTIVEDVSQGSTMAMKDGKVYIAYLSSNFKLKMA
                     IGNGTGWVVQDVDSTSAFSKYLAIDILNGYPCVVYYSTISQDLKIATTSGTAWDTQVV
                     DDVTSVAYGVSVNVDSLQRIHIVYSDAALDLRYAIYNGTWNYFILDASVGNFKSIVSD
                     VNDKQHVVYIDREPTYYQLGYLTNSGAKWLIKDIDSSGGADKFSSIAVDAMGFAHIAF
                     YDTYVDNNVTKGRLCHATSANGWQVETVDISASAVPNHPSVVVDSHGFVHISYWDAAI
                     GGTLKYATNADGPWKNYTLDALGNIGKSTSIAVDSTGTVHIVYTYHTPNPANNVLKYA
                     NFSSEAGLNTGSIETGVVTNGQVALVADSEDHLHVAYYKEGELHYAIKSGATWGDAES
                     VDTSDQLGGGISMYVNAAGNVFITYYDNGLSKLMYVNNTGGSWVSQDIALAAGGASAI
                     FVDEEGDEHISYLETNTPNGILKYKERRNGIWMDQNIDLTGCSPQISMAMDSLGRGHV
                     SYFDPSTKVLKYATSIMAPSAPTNLTIDVESNKLTLNWAAPKVDGGSSIIEYRIFRSV
                     AGGEYLFLDAVLAPGLAYIDDGLEDGVTYSYYIRAVNAEGTGELSEFVSGIPCREPQA
                     PVLKASGQDKAVKLTWNEPENGGADITGYKIYRKNATGVFELLVELGGNTRSYTDKQL
                     ENGQEYSYYIKAFNPAGPSVDSAVASATPEESNTLMIIAIVIIVLAAVGVGAFVFLKK
                     SGRI"
     gene            54926..56347
                     /locus_tag="PKM11_01290"
     CDS             54926..56347
                     /locus_tag="PKM11_01290"
                     /inference="COORDINATES: protein motif:HMM:NF003229.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication factor C large subunit"
                     /protein_id="HNX47178.1"
                     /translation="MADDWTELYRPQGLSEVVGNPKVIKDLQQWAVSWEEGRPEFKAV
                     VLMGPPGVGKTSAALALARDFKWGVVEMNASDQRNADAIKKVAIRGSRSETFNDEGEF
                     LSSKDGHLKLIILDEADNIFGREDSGGIPAIAELVAKTRQPVILIVNDFYELSRKSSA
                     IKNNTLQLKVSKVQGATMRNVLRRIALDQELEVPHRVFETIIENSNGDMRAAVRDLQA
                     VGEGNANMGEDDAFVLESRMSIRSMYDLMRDILHESDSRRARRTAMDVDETPEHIMMW
                     LDENVPMEYKDPEDLYRALTHLARSSTFLARVTRRQYYGFWSYANDHNVMGVCSAKSR
                     PYRGWVQYRFPSYIMKMSRSKAFRSMKSGIASKISEHTHTSTRRSAQDVLPYFIEMFK
                     ADPEFRLTMINTLRLNTEEVAFILDKKVDSSEVKKLMLESEKAKASMEPVPKSIPEPV
                     EEKEEKPERRPEPKGKQASLFEY"
     gene            56355..57296
                     /gene="twy1"
                     /locus_tag="PKM11_01295"
     CDS             56355..57296
                     /gene="twy1"
                     /locus_tag="PKM11_01295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-demethylwyosine synthase TYW1"
                     /protein_id="HNX47179.1"
                     /translation="MKDDLREILQKQQYRLCGDHAGVKLCHWMKQSLLKGRTCYKQDF
                     YGIRSHRCLQMTPAVNDCTHNCLFCWRVRGFESTVTKWQDPETVLDTCIEGQRQLVTG
                     FKGDPRCSPAMWEEARQPRQVAISLAGEPTIYPYLGDFIELCHRRGMTTFLVTNGTFP
                     KVLEELSELPTQLYVTVAAPNKDIYKKLCVPQIDDGWERLMETLELLPSLNTRTVIRH
                     TLVKDWNLGWEKEYAALDRKADPTFVEPKGFVFVGDSRRRMSMDNMPSHSEVLEFGRR
                     VADELGMCMLREKSDSRVAVFGESGTDTKIPGLDQSE"
     gene            complement(57284..58075)
                     /locus_tag="PKM11_01300"
     CDS             complement(57284..58075)
                     /locus_tag="PKM11_01300"
                     /inference="COORDINATES: protein motif:HMM:NF023568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HNX47180.1"
                     /translation="MPKVEIGNARINYETHGEGEPIVLITGLGGEIAFWKKYVPLLSR
                     SHQVVVFDNRGAGETDYPPTLFTMSTLADDVAGLMEHLGHQRYHVLGWSMGGNVAQRV
                     AIDHPEKVGALVLMSTYTRRPERSSFAIDTMIRTVDEGATFDSLMDLMQSWCLPEDYF
                     KKLALSKPAQRKCNGNGKRAAEGFKAQKLALDLFDSHDLLDKIIAPTLIIHGDEDIMV
                     APHFATELASHIEGAELIWVPGAGHNIPADKCCSSILKWLNAHSL"
     gene            complement(58124..59230)
                     /locus_tag="PKM11_01305"
     CDS             complement(58124..59230)
                     /locus_tag="PKM11_01305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47181.1"
                     /translation="MEQPSVLTFEDSVLDFSEESRAELARQQDLLDLVKDERKDQWRG
                     TILPLMLMTFTGVFIFLYPKALWSWFISGLVLYSWNFLFLLLPTTRKVVHNSGNVVRQ
                     KKSKEQRKLAYRRLLNKPKLTVEILITVFLGRMVPLTVGFTLILGTGMIVLFGFILTD
                     YKAVAGLANLMIFQVVLIFIFYSLVNFLEPQTQGMTDIARSWKRRIGMAKLKGRAASF
                     MVKAAAVAVLLILAIIFTAAMVLPSYTFLTLVTSLKEYHIWDVLLFIGIFIEQFWIMR
                     TFQSMMSLRTANQALYNKIDKLQELMARANEISSRTEEDLARCDAMLQVTREYYALML
                     YDIYRTDLFGRLPVYLVGPRKKYIFDEKVLSHLP"
     gene            59358..59555
                     /locus_tag="PKM11_01310"
     CDS             59358..59555
                     /locus_tag="PKM11_01310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47182.1"
                     /translation="MGKKEKMASMLHLVGGKPENVEKIVDEIDMFFDTMNAELEDWKL
                     SMEEFPDGTRIYARFQVLVKK"
     gene            59565..60260
                     /locus_tag="PKM11_01315"
     CDS             59565..60260
                     /locus_tag="PKM11_01315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47183.1"
                     /translation="MPEEEEAPRERVLMCAADWKDPECRTVIGEFHKEGIDAEILDVD
                     LDLQGFEKAWGDKGQAKFQSEYHKEGAPYLGEDGLNLYVPIGPVERTGRSPKDAVLNR
                     KLDVGTVEVITYALFRAIFGYGVNVPIKRPGVVDMDVTIKGKDINVNTNDFFFNVPDL
                     VVWKVVYSHQGTPIMEFGRGVDKGFKVHRLQALKLFLALRSKSKRATKARMAARKAAA
                     ENDDDEEVTKGTR"
     gene            60260..61075
                     /locus_tag="PKM11_01320"
     CDS             60260..61075
                     /locus_tag="PKM11_01320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47184.1"
                     /translation="MSPVQDDQREHFRDVLRSIHLIMVESFKLRQVKVTPLGSEGSRL
                     SIPIKIEGVDRTGSPARYFAKILGGSDIMTEKTIQFFKNVYLQMEGRSPLFNFNRSAK
                     DLALHQFEIMSQVYRLGIPTAKPLGTFALPGGMWLFVAEFLEAASSATKKVSEAQLDK
                     AFEHLRLMHKNGIYHGDIKPENFLFADQVYIMDVGNFLKDAPEKEKLSYDLACALASF
                     LDLASPEKLVKLARGYYGVRDLKRAAGYLELIDRRPDFKMAPEKMKRLMELLS"
     gene            complement(61072..61248)
                     /locus_tag="PKM11_01325"
     CDS             complement(61072..61248)
                     /locus_tag="PKM11_01325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47185.1"
                     /translation="MPEKDVTVVLNEKGQELKKLFKDYNANIEQWKFSVEETKDGIRV
                     EFAAKALFKKKASD"
     gene            complement(61305..62957)
                     /locus_tag="PKM11_01330"
     CDS             complement(61305..62957)
                     /locus_tag="PKM11_01330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HNX47186.1"
                     /translation="MPRENITREATIGQLLDEIVDVVPDQDAVVYADRDYRQTWREFR
                     ETVDKAAKGLMALGVKKGDKVAMWATNVPHWVTLQFATARIGAILLTININYRSAEID
                     YLLRQSDCENIFVIDGYRDTDYVNTLYELIPELKTQPRDRLRSERYPHLRRVLFLGPE
                     KHRGMYSWNELLAMSVAVSDDDYRQRQSELSTYDVVNMQYTSGTTGFPKGVMLTHFNL
                     TNNGYWVGVNENFTTADRVCIPVPLFHCFGCVLAVMACLNHGATMVILERYDPINVMM
                     SIEKERCTALYGVPTMFIGILDHKLFDKFDFSTLRTGIMAGSPCPVKTMEECVERMNM
                     REVTIVFGLTESSPAMTQTRYDEPSLEKKCSTVGKAFPGIEVAIIDPETGEHLGPGKH
                     GELCCRGHNVMKGYYKMPEETAKAIDKDGWLHSGDIGMMDEDGYYAVTGRLKDMIIRG
                     GENIYPKEVEDFIHHMDGVADVQVVGVPSVKYGELPAAFVVLRPGVKLTAEDIMDHCR
                     GKIAFYKIPKFVHFVEEYPMTASGKIMKMKLREMSATLWPDA"
     gene            complement(62967..63530)
                     /locus_tag="PKM11_01335"
     CDS             complement(62967..63530)
                     /locus_tag="PKM11_01335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HNX47187.1"
                     /translation="MTTPDKLGTRIRTYRERLNMSVEDLAMNAGVDASLVRNAEEGEV
                     YPPLGVLVKISRALGQRLGTFMDDQFRPDPVITRFKDRAEETAAHKEGAVGKYHYYPL
                     AKGKTDRHMEPLYIIVQPCEDCSTSSHEGEEFVIVVKGQVELVYGKERHLLQEGDSMH
                     YNSVVPHHLGAANGEAAEIFAVIYTPI"
     gene            complement(63671..65068)
                     /locus_tag="PKM11_01340"
     CDS             complement(63671..65068)
                     /locus_tag="PKM11_01340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HNX47188.1"
                     /translation="MIKKAQGFYETFDRKEPGTRATHYCPGCGHGIIQKLIAEAMAEL
                     GIQDRTVFVTPVGCAAFSFHYFDCGNVAGPHGRASAVATGVTRALPGKVVISYQGDGD
                     LGAIGFNNAFQAANRGEHFACFFVNNSIYGMTGGQMAPTTMIGQKTTTTPFGRDPVKE
                     GYPLKVCEVLNQLEAPVFIERVSVSDTKHIMQAKKAVRKALEVQRDGKGYAFVEFLSP
                     CPTNWRLDPVASAQFVNENMEKVFPLGNFRDRSAEPAPVANVIPQLTVDELLGKGHEG
                     VSAKVDGQFKERKFKFSGFGGQGVLSLGLVVAEAAGGSGRFVSWLPSYGPEQRGGYAS
                     CSVVVSGKEVGSPTVDAPDVLVVMSQPAAEKFSMTVPEGGVVIYEASLPKPTVRAGVR
                     VMAFPASRLAAEAGTPKAANTALLGGLTALGLHGLPEDKVLQALDASFATKPALVERN
                     RKVYRAAFDWAKNNL"
     gene            complement(65065..66117)
                     /gene="vorB"
                     /locus_tag="PKM11_01345"
     CDS             complement(65065..66117)
                     /gene="vorB"
                     /locus_tag="PKM11_01345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HNX47189.1"
                     /translation="MRKFVKGNEAVAIGAVYAGCDTYFGYPITPASDIAHAVAEYFPQ
                     LGREHLQAECETGAINMMFGAAATGKLTMTASSGPGISLMQEGMSYLAGAQLPAVIVN
                     VQRVGPGLGNIGPEQGDYNQAVRGGGHGNYHSIVLAPASVQEMCDLTIKAFELSFKYR
                     NPAIVLADAVLGQMMEFLQLPEKVSARPETSWSVQGDAATRGNLVSSIYLDNELQERH
                     NWMLQERYASMQDDVLCESYRTEDAEIVLTGYGTSSRVARSAVDQLRSQGIKAGLFRP
                     LTLFPFPTKALNEVAKAGKILVVELSNGQYRDDVLLHLDRDIKCEVQLLNRMGGNVMK
                     VEDVVLRARQMLEVRA"
     gene            complement(66114..66350)
                     /locus_tag="PKM11_01350"
     CDS             complement(66114..66350)
                     /locus_tag="PKM11_01350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HNX47190.1"
                     /translation="MSTEKRISRPIVDENECKGCGRCVAACPKKVLRLSGRINRRGYS
                     AVEYLGEGCTGCAACFYNCPEPYALQVDDGRDPQ"
     gene            complement(66415..67218)
                     /locus_tag="PKM11_01355"
     CDS             complement(66415..67218)
                     /locus_tag="PKM11_01355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX47191.1"
                     /translation="MSADLRRKITDRCRDWGIEMVGFASADDWDDPPFVPFPPREFSP
                     KAIFPGCRTVVVLGLPVTLPILETSPSIWYQELYKNLNAQLDERAYQLSELLNRLGHA
                     SVYVPRDGYGSVEVLVDNPYAFFSHRHAAYLAGLGTFGLNNMLLTREFGPRVRFVSVF
                     TTAKISPGKPMDRNLCVRCRRCIEACPVEAIGDVDYPKASIDKKRCTGRSISLKKKYR
                     SPCGICIKVCPVGEDRRLFERKDLGLYDGPDKDPELYEAWEHVRRYGSL"
     gene            complement(67260..68258)
                     /locus_tag="PKM11_01360"
     CDS             complement(67260..68258)
                     /locus_tag="PKM11_01360"
                     /inference="COORDINATES: protein motif:HMM:NF012407.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HNX47192.1"
                     /translation="MTRVAVMGGDGIGPEVVGATMSILEQMDLDLEFVKAYMGLNCYE
                     RTGEYLPAQTLRTLESSKAVLFGAITSPVTPDPGYRSPLLQLRKHFDLYANIRPCFPM
                     LPEYKLVDLNTVIVRENTEGMYTGREREEDGAVILERVVSEKGCRRIVEKAIKVSRVM
                     GFNKITCVHKANVLRKSDGLFRRVFYEVMKDSGLEADDMIVDAVAAALISKPKQFQCI
                     VTLNLYGDILSDEAAALTGGLGMAPSANLSDRFGLFEPVHGSAPDIAGKDIANPSATI
                     LSACLMLEFLKKMDAASRLQSALVQTLTEGDRTRDLGGTLGTREFAERVAERLTRS"
     gene            complement(68255..69187)
                     /locus_tag="PKM11_01365"
     CDS             complement(68255..69187)
                     /locus_tag="PKM11_01365"
                     /EC_number="2.5.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyhypusine synthase"
                     /protein_id="HNX47193.1"
                     /translation="MEERAVRDIKVTEGMTVDQLVRAMSDSGGFTAKKLADATDIVEK
                     MVKDEKCLTFLSFPACIMATGTRGVIVELVKRKLVDVVITTCGTLDHDLARSWKHYYH
                     GDFAMDDAELREEGYNRLGNVLVPDESYGLVLEERLIPMFEEILAGRSSISTREIIDQ
                     VGARLDNEDSLLYWAHKNKIPIFVPGITDGSFGSQIWMYWQTHRDLKIDLFEDEQELS
                     SLVFHAEASGALIIGGGISKHHVIWWNQFRGGLDYAVYMTTATEYDGSLSGAQVREAI
                     SWGKVREDAWQVNVEGDATITLPILVASIVERLK"
     gene            69293..70468
                     /locus_tag="PKM11_01370"
     CDS             69293..70468
                     /locus_tag="PKM11_01370"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47194.1"
                     /translation="MDTKRLAVLSGGYIGPLSGNAVLAMIPVLKTDFGASAEEILVSI
                     TFFMLPFVIFNLFSGTISDVYGRRKMLTFGFLIYALGCLFCVASSDLMTFYLSRSVQG
                     IGYAFVNPVLLAILGDMTPPNERGKVMGYFGAFTTAGIATGPMIAGFLTEYDWRWMFV
                     LVAVLAVVVNFWIRSACPVSRTNPEALRHLKSNVITAVTSKGVGTLCLLGFLTFLCYM
                     GALGFLSDHLSVPPLSLDEGTIGLLIGMSGVAGMVAAPLGGRLVDAKGRTFTASVGFA
                     VVGLSLAFLYLSSDWIHFAGSLLVLGTGTAFIWASLLTITVEIVPQLKGTVSSVFNST
                     RFFGYSLAPLIFAPIYSVDGFGAVLLIGIALTLVSFPVVFWLGAQLRASQSDNTNFS"
     gene            complement(70426..71004)
                     /locus_tag="PKM11_01375"
     CDS             complement(70426..71004)
                     /locus_tag="PKM11_01375"
                     /inference="COORDINATES: protein motif:HMM:NF014299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HNX47195.1"
                     /translation="MELIVVDGIDGSGKSTVAEWIAEHYRSRGEKVLVRQHPSDSFYG
                     RLSRRSLTSEGKMMRTVATIFFILDVLNSLRRLRGWKDHDKVIFVRYIMATAYLPTPL
                     YRQGYEFFCKVLPIPERLLLVDVNPECALRRIEEREHEREMFENLRSLEKVRGKVLDL
                     SSRGWKVLDNCGSVENTRSQLKLVLSDWDALN"
     gene            complement(71014..71742)
                     /locus_tag="PKM11_01380"
     CDS             complement(71014..71742)
                     /locus_tag="PKM11_01380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47196.1"
                     /translation="MIGGDALGLILVYVYVGVMVVITDRWRFLRDHSFHRKFIHVMIG
                     NIALFWWVFDTNYVMSLLAAVPFIPLLYIFSKYGGRREKDDSKLIGELKGSILSTASH
                     DGHKLGLVYYAISWALLAFFAFNDLVVASVAIVCMAYGDGLGGQFGKTFGKRKIHGNK
                     TLEGTLAVFVFAALAIFLIINFYNLLFTEGLYGTRSIPLAISALTALGLGAFVSVVEL
                     YTPGEYDNLVIPLSTALIMFLAGI"
     gene            71989..74121
                     /locus_tag="PKM11_01385"
     CDS             71989..74121
                     /locus_tag="PKM11_01385"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-translocating pyrophosphatase"
                     /protein_id="HNX47197.1"
                     /translation="MLDDPLYYTIPIAGIIGLLFAGYLTWWILKKDTGTPEMKAISDA
                     IREGAMAYLARQYKTIAIISVILGILITVGINLWTGVAFLLGAFFSALSGYIGMYVSV
                     SSNIRTASAARRSLNEALLTSFRGGAVSGIAVVALSLMGVAGIFFVYQAYVAVGPADS
                     ATLYMDALFLAVGYAFGASFAALFAQLGGGIYTKAADVGADLVGKVEAGIPEDDPRNP
                     AVIADLVGDNVGDCAGRGADLFESTAAENIGAMILGIAIFAFTGNPGWFMFPLVVRGF
                     GLLAGLVGIMTVRMKNEDENPMKAINRGYYVTCVIAAILFYIAVDQLLAGEMLFFVCG
                     LVGIALSIVIVYITQYYTAGEYRPVKKIAKASETGPATNIIAGISIGMETTAMSVMAI
                     AIALIASFELGVMASPDAAHEFIYGLYGTAVATMGMLATCAFVLAEDTFGPITDNAGG
                     IVEMSGQPEEVRVRTDRLDSIGNTTKALTKGYAMGAAALAAYLLFGAFFEQVAKIRGV
                     DILAFYDSFTVDLLQPVVFVSAMIGAMLVYLFTSLAISAVGKAAGNMIEEVRRQFRER
                     PGILAGTEKPDYATCVDISTKGALKAMILPGILPVVVPVALGLTLRYAYPDNNDIAVM
                     GVGAFLMVATIAGVLMALFLNNGGGAWDNAKKYIESQGKKGTPQHAAGVVGDTVGDPF
                     KDTAGPSLHVLVKLLSTITLVFAVLFVV"
     gene            74238..74804
                     /locus_tag="PKM11_01390"
     CDS             74238..74804
                     /locus_tag="PKM11_01390"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HNX47198.1"
                     /translation="MYMLTQREKVVRIPPSRLGDDVDEVVNELARESYEGKIEGDDSL
                     TVMIQNIEPVGEGRIVHGDGAVYQSVKFDSLVFKPLVNEVVEGHVCEVLKFGAFVRFG
                     PLDGLLHVSQVMDDRMDADEQNQRLIGKDTKREIRIGDIVRTRIVTLSFNERNPRESK
                     IGLTMRQPGLGKKEWIAEDRAKKGGQEK"
     gene            74801..74989
                     /gene="spt4"
                     /locus_tag="PKM11_01395"
     CDS             74801..74989
                     /gene="spt4"
                     /locus_tag="PKM11_01395"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003711 - transcription elongation factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor subunit Spt4"
                     /protein_id="HNX47199.1"
                     /translation="MKGVVKACKVCFAITEEDKCPLCGGETSKDWQGYVVIIDHTKSE
                     IAKRMNIDKNGKFALKVR"
     gene            75048..75512
                     /locus_tag="PKM11_01400"
     CDS             75048..75512
                     /locus_tag="PKM11_01400"
                     /inference="COORDINATES: protein motif:HMM:NF015952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-dependent dephospho-CoA kinase family
                     protein"
                     /protein_id="HNX47200.1"
                     /translation="MPFGSLFRGEDVLEALSDCGMLITVGDVVSSTFINKGVIPHLTV
                     YDRRNERKELEAGEHPADLLQVPETNVENPPGSITPGLVKAMKDGLESPGKTKVRVIG
                     EEDLAALVCAAIAPAGSCLVYGLPGKGVVLVHTNAKVNHAAQNLIRSMEVLK"
     gene            75509..75814
                     /locus_tag="PKM11_01405"
     CDS             75509..75814
                     /locus_tag="PKM11_01405"
                     /inference="COORDINATES: protein motif:HMM:NF013450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47201.1"
                     /translation="MKIEIESKKPNALMDRTEVNFKADHSGEGSPKRADVKAKLAEVL
                     AVSKDKVIIDHMETEFGMGVSTGYAKVYGSTESAKKFEKNYLQARNGLAEAKKTKKK"
     gene            75825..76019
                     /locus_tag="PKM11_01410"
     CDS             75825..76019
                     /locus_tag="PKM11_01410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S27ae"
                     /protein_id="HNX47202.1"
                     /translation="MAAPKKKEVKKEAPSAKKDYYQAKGEKLERLKKSCPKCGPGVFM
                     GEHKDRTSCGKCGYTEFKKK"
     gene            76083..76156
                     /locus_tag="PKM11_01415"
     tRNA            76083..76156
                     /locus_tag="PKM11_01415"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:76118..76120,aa:Arg,seq:ccg)
     gene            76211..77377
                     /locus_tag="PKM11_01420"
     CDS             76211..77377
                     /locus_tag="PKM11_01420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitase X catalytic domain-containing protein"
                     /protein_id="HNX47203.1"
                     /translation="MQLTSEEQDMLAGKQGKAKRKAMELLVALGAIYGADRLIPITSA
                     HLSGVSYKTIGEGGIDFLEEMAADGKVCVPTTLNPMGMDGERWKEMGVDEHFAQRQMH
                     IISLYEKMGVEVSCTCTPYLLTNRPKVGDHIAWAESSALSFANSVLGARTNREGGPGA
                     LAAAITGRTPNYGLHLDQNRKATHVVVVEKGITKDEWSLVGHSVGRKLGACIPFFRGL
                     GSDVNGLKSLAAAMAAAGSVAMFMVEKATPEQPDTLEGLPVVNITREDIEDTVKRLRT
                     GKKPDLIAIGCPHLSESEMKELADLLDGKKKKGDVEVWFCTSKGIWLRCPKERAVLER
                     FGKVLCDTCMVVAPIEVGHKVTASDSAKACAYLPGLCSQKVFCGSRRELMELIL"
     gene            77374..78147
                     /locus_tag="PKM11_01425"
     CDS             77374..78147
                     /locus_tag="PKM11_01425"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF126 domain-containing protein"
                     /protein_id="HNX47204.1"
                     /translation="MKLKGREICKGKAIGRLLILDEAFSFLGGVDPKTGLLTVASGRE
                     GESVDNRILVFPYGKGSTVGSYTIMELKKNGHLPAAIVNAQAETIVATGAVMAGVPMI
                     DSIDISLLREGDRAVIVGDGLDMMDLVEKKVVTCVLRRKGKILLLKRSQKVGTNKGKW
                     AAVSGYIERGEKPEETALKEVDEETGITSARLEAMAERLRIRDGTYVWSVYPFLFEVA
                     DEKVILDWEHTECAWVDPAELDGYETVPGFRKVLEALGL"
     gene            complement(78142..82302)
                     /gene="ileS"
                     /locus_tag="PKM11_01430"
     CDS             complement(78142..82302)
                     /gene="ileS"
                     /locus_tag="PKM11_01430"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HNX47205.1"
                     /translation="MIKQVQGNYNPSALEKSVQALWAETEAYKKTKELRASGPDFYFV
                     DGPPYTTGYIHLGTAMNKTIKDMIVRFKRMQKFNVSDTPGYDMHGLPIEVKVEKSIGV
                     KNKKEIEAYGIDRFVSTCKNFALDFQKQMNADFKELGVWFDWEKPYLTIAPNYIEAAW
                     WTLRRAYDKGLLISASRVLPGCPRCETALAEAEIDYWDEKDPSIYVKFRLKDDPKVSL
                     LIWTTTPWTLPANLAVAAHPDFEYVKVRYRKVGVTETIIIMKGLEEEIRNLGGWEKYD
                     VLQTIQGDDLVGVEYITPFVDDVPYQTQATGKWLHKVLPSKTVEASNTGLVHIAPGHG
                     PEDFELGKEFGLEPFCPVDETGVYTPLVGSKYVGMHIKKANPDLIKDLEEKDRLFFSG
                     TIEHRFGHCWRCKSPVLFRTTDQWFLRVTQVKNQMLEEIEKVRWTPDWAGSSREYDWT
                     MNARDWCISRQRYWGIPIPVWTCSCGEMRVVGMVDELKGAEGYVEDMELHRPWIDSVK
                     LACPKCGGKMSRVPDVLDVWFDSAVASWAQLGFPKKRDAFERLWPAKFIVEAHDQTRG
                     WFYSQLAAGVIAFGRAPYESVLMHGWMLDSQGQPMSKSKGNVVEPGKVIKEHGADALR
                     FYLLKTSAPWEDIPFQMEGVKNARKTLNVFWNVVNFATTYMAIDHFDAQRITKETVRA
                     HLNQEDLWLISRTEKLKNEFTRQVNALELHKAGRALEQFILDDLSRWYVRLIRDRMWS
                     EEGDVGKLAAYRTLFDAIMDTTLLLAPMCPHLAEEVYRHMDGSKPTVHMMDWPSSDLT
                     RVDERLEKAMAMVQEIVDTVTRERQLKNVKLRWPMKRIVIKVDSNDTLISLRALESIL
                     KSQANVKEIEYVGTGEEWSETILNVVPNPMAIGKVYRQWASKIAVLLQSRPAGLIKES
                     MQRGEYSLGIEGQLVKIEPNMVSFTVSLPKDIYAATFSGGEIYLDFEVTREIEAEGFS
                     REIIRRVQQTRKEMKLDVEEFVKVEVLADTKVAEYVKMWKSHIMSEVRSKSMELVFEV
                     HGEQVGKWEIEGEKVEIGVSSMNLRDPIKELTKIPGITPKAAEALVDAGVRNEADLKQ
                     LGEDRIEDITKLSKAEVRKALHYTDRSAEICKAVPEGSGKIMDRSEMTPYLLRIPRMN
                     EVKAEMLYDAGYDSLDKLQAADKDALKNVPGLGSKTIDEVLKYVSDGGFQRCSACATC
                     GHEVTAKELNCPACGASLRAEVTEEETEAPKAQGLQDGYSYLIKDDRSDRSYELFMEQ
                     LKLGKRGFCITRNYPVKIRNKFDLGETPIVWLSNVGKEDSLRPKDLEKLSYSLEQFLA
                     KGQGVVLLDGLEYLITNNNFLTVLRFVQSLRDQVAINNSIMMMVLNPSTIDANELNLL
                     EKEIDGTL"
     gene            complement(82386..83396)
                     /gene="fen"
                     /locus_tag="PKM11_01435"
     CDS             complement(82386..83396)
                     /gene="fen"
                     /locus_tag="PKM11_01435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease-1"
                     /protein_id="HNX47206.1"
                     /translation="MGVNLSDLVLAKDLETQNLMGRTVAIDAYNAIYQFLSVIRQPDG
                     TPLMDPRGRITSHLEGLLNRNANLAEMGLRSAYVFDGIPPEKKEATIRERRERRESAK
                     KEWEQAKAEGDVRKAYSKATQSSRITNEIVESSRILLTHLGIPVVQAPEEGEAQAAYM
                     CAKGDVWASASQDFDSLLFGAPRLVRNLTLSGRRKMPGKDEYREVRMQIIDRDETLSS
                     LGLNGKQLVDLCILVGTDFNPGVMGIGPKKALKLIKQYGTLAGALRSLGLEEGEMEKV
                     RSIFLDFERTDDYRLAWRSPDRQSVLDMLCGEYGFSEKRVNGALDKFSSGKKDQMRLD
                     MF"
     gene            83461..83670
                     /locus_tag="PKM11_01440"
     CDS             83461..83670
                     /locus_tag="PKM11_01440"
                     /inference="COORDINATES: protein motif:HMM:NF014047.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAM domain-containing protein"
                     /protein_id="HNX47207.1"
                     /translation="MRDEHAEPERKPVTEGQIYEVKITDIGERGDGIGKIEGLVIIVP
                     DTTTGETVKVRITRVEKKVAFGRRT"
     gene            complement(83671..83844)
                     /locus_tag="PKM11_01445"
     CDS             complement(83671..83844)
                     /locus_tag="PKM11_01445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47208.1"
                     /translation="MYMKMSGKQMVIFLTVIAPLMFLLAALIITPNIWVIILALMWLG
                     IGLTMLYIPKAED"
     gene            complement(83888..84298)
                     /locus_tag="PKM11_01450"
     CDS             complement(83888..84298)
                     /locus_tag="PKM11_01450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47209.1"
                     /translation="MARIGSKKSLVAKLGIKEGQRIRIINAPSKYDVALGRLPKNVVE
                     AGSGDSELDFIQLFTSSEDELRREFPKLMRALKKEGIIWISYPRTSSKIDSDLVGVTV
                     RSIGTGHGMAEVKISSLDEDWAGIKFVNKKKELD"
     gene            complement(84404..85051)
                     /gene="rpe"
                     /locus_tag="PKM11_01455"
     CDS             complement(84404..85051)
                     /gene="rpe"
                     /locus_tag="PKM11_01455"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HNX47210.1"
                     /translation="MVKVAPSILSADFARLGEEIRRVEAAQADWIHIDVMDGVFVPNL
                     TIGPEVIKALRPHAKIPFDVHLMIEMPERYVERFAECGANYLTVHVEATHDVKGVLAH
                     IRRLGMKAGISLNPGTELSTVEPYFNDIDLLLVMTVQPGFGGQSFRSEVLPKISQARR
                     IRDERKLNFEIVIDGGINRETGKLCVENGATVLAAGSALFKAKDMAAEIDLWHMY"
     gene            85296..85523
                     /locus_tag="PKM11_01460"
     CDS             85296..85523
                     /locus_tag="PKM11_01460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47211.1"
                     /translation="MAEARHAIKVSKTCDVKGCSSEAERSISGDAATEAKLKVEDGMK
                     RVHLCKEHYREYKKVSRKDRELGSLGRSFGK"
     gene            85552..86658
                     /locus_tag="PKM11_01465"
     CDS             85552..86658
                     /locus_tag="PKM11_01465"
                     /inference="COORDINATES: protein motif:HMM:NF024241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47212.1"
                     /translation="MKAGYIQLLSSAGLSGAALLIPNMLRDDLGANTMEIGLITASFN
                     LALFASSYIFGRASDVHGRKLYLQGGLALTAIALFLLVFANSKETIAVVRIMIGLCAG
                     IYPSALLTYVYETEGKIGKFTAYGSLGFGIGTFIAGILTIYYEIFLASGIMLLVAYFI
                     STRLMFVGEKVHQVPLFPVAMIRHNFPVYISIMFRHTGANMIWVVYPLFLADLGATPL
                     FIGAVYGVNAIAQYVFMRYIDRFKTYHLVMAGFLFSIITFPSYTLATRPEEILPMQVS
                     IAAAWSCLYVGSIKYLMERNEEKGTSSGLLQSFLSISAIIGALVGGVTVFALGYHGAM
                     YIATILAILGFVVFMIGNRFMSGKEKGIIAPKGV"
     gene            86665..87573
                     /gene="rnz"
                     /locus_tag="PKM11_01470"
     CDS             86665..87573
                     /gene="rnz"
                     /locus_tag="PKM11_01470"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: protein motif:HMM:NF000801.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - endoribonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042779 - tRNA 3'-trailer cleavage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HNX47213.1"
                     /translation="MDLTFLGTGGSVPTTKRNTVSIALRLGPEVLMFDCGEGTQRQLM
                     ASSVSFMKITNIFISHHHGDHFLGLPGLIQSMNFYGREAPLNVYGPIGTQEMVKTILR
                     LGIFDRKYEVQGHDLAPGEVVIGDGYQVAAFKANHTTPALGYAFQENDRPGRFDPDKA
                     KALGVREGPNFSRLVEGYSVQVGSSKVTPDMVMGPSRKGLRLVYSGDTAASSELDQAC
                     VDADVLIHEATVASDLEAKAREFGHSTAKDAALLARDSGVGALYLVHISGRYEDVDVL
                     LEEARGIFGPTTIPNDLDMFVLRTDR"
     gene            complement(87592..88155)
                     /locus_tag="PKM11_01475"
     CDS             complement(87592..88155)
                     /locus_tag="PKM11_01475"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX47214.1"
                     /translation="MKFPPEGEIKRLRKSLDITQQELAKLSGVSQSTIAKLERGSLRG
                     SYEAVTKLFDALREESRRHSKASKASDLATRQIVGVQSNELVKAATELMRSSGISQMP
                     VFLGRQHVGSVSENQILSRLRDGERMETIVELKVSDIMEDAFPIVNEDTPIEAVTALL
                     SSSHAVMVGRNGDMTGIITSADLLKML"
     gene            88281..89579
                     /locus_tag="PKM11_01480"
     CDS             88281..89579
                     /locus_tag="PKM11_01480"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: protein motif:HMM:NF003364.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HNX47215.1"
                     /translation="MAKVSAKAKATAKTVGRKVSPKKVSKNIVVESMRATPLAQQNIE
                     LVERKGIGHPDSISDGIAEAVSLALCKMYLERFGEILHHNTDQNEVVGGQSAPKFAGG
                     EVLEPIHIMLSGRAITQVNGERLPYSTTAINATKEYLKRFPNLDVNRHITVDCRIGKG
                     SFDLIKNFEALKDQCKMDGRGNHCLLANDTSFGCSFAPYSDTELVCLETEKYINGAMK
                     KKLKETGEDVKVMCSRNGKKINMTIACAMVDRYVPDADHYASVIEEMHERVLDNATKY
                     TDYDLALAINHADNPATGNFYLTVTGLSAENGDDGSVGRGNRMNGLITPYRTMSMEAS
                     AGKNPITHVGKMYNILANWIANDIVKKSNGNIVEADVRILSQIGRPISDPETCSVQLF
                     LAPGADEAKWQKEAYAISDEWLENINKVTEKVVKGQVTVF"
     gene            89583..90167
                     /locus_tag="PKM11_01485"
     CDS             89583..90167
                     /locus_tag="PKM11_01485"
                     /inference="COORDINATES: protein motif:HMM:NF025897.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4443 domain-containing protein"
                     /protein_id="HNX47216.1"
                     /translation="MKLVDLPRYGPVHRFGNHHVYRTLMVLSDQKRKGRKQIAEAVGI
                     GEGSMRTIIEYLRGLDMIEIHQTGVKITRHGNAFLSDLPIKLADIGHGSIALGKECVA
                     VQMGNNGNKIKMGVEQRDSAIMAGAEGATTLVVIDGKLIVPPDYVIDEHDPNLAKLLH
                     EKFNLREGDAIIIGTASTVSKAEDGALAAAFDLL"
     gene            complement(90159..92159)
                     /locus_tag="PKM11_01490"
     CDS             complement(90159..92159)
                     /locus_tag="PKM11_01490"
                     /inference="COORDINATES: protein motif:HMM:NF015168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HNX47217.1"
                     /translation="MAGPTNRLATERSPYLLQHSRNPVDWYPWGSEAFEEAEWLDRPI
                     LLSIGYSSCHWCHVMERECFEDQDVSTMMNDWFICVKVDREERPDVDSLYMKVCQMMT
                     GGGGWPLTILMTPERVPFWAGTYLPKRSRQGMTGMIDLLPAVHRAWQEGREGIKDVAV
                     KVLEMLDSFERDPAEGDVSELIELTLQHLSEDFEPRYGGFDGERKFPSPHKLLFLLRV
                     FRERKDQKAMDMALKTLDNIVRGGIRDHLGGGFHRYSTDHRWHLPHFEKMLYDQALIL
                     MALTEAFAATRDEEYRQAANELIGYVKRDLTSAEGAFFSSEDADSDGTEGAFYLWKFE
                     ELAASLSPDDLVRFRELYDIWESGNFRDEATRTRSGVNVLHRLKTIQEFASLKGMEPE
                     EMRAWDEKVREELRSKRDKRARPALDDKVLTDWNGLMIVALCKAHRLLGSEDAINMAA
                     QALGLLEKELVKDGALYHTYRQGEVGVPSLLDDHACLAWAHLEMYFATLKKEHLERSM
                     DIVEGMMVLFLDREDGGFYLSRDDPHLLIRMKDLYDGASPSGNSVAYYVLAQLAALFN
                     DPRTVEALEGVERHFMRELHLTPSAYAMFMCGVLMKEESRTLEVFGDSDTRFLGYHPH
                     LLIVKAEHLEGLPALPAGYRLCMKGRCLPETDDKKEIERLLE"
     gene            92294..93505
                     /locus_tag="PKM11_01495"
     CDS             92294..93505
                     /locus_tag="PKM11_01495"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47218.1"
                     /translation="MNIRKWLGGGRVSASVSESKSLRYATVFILLLGVVSLFADMSYE
                     GAKSISGSYLKTLGASAATVALVAGFGEFIGYGWRVVSGHVADRTGRYWTIVLVGYAM
                     NLLAIPLLAFAGNWYMVAILIVLERMGKAIRSPARDAMMSHAATKTGRGWAFGVQEAL
                     SSVGAMIGPISIFLVFLMGGGYSTAFLLMGVPAILTLIVLYYTYKKYPKPQLMEAVQP
                     QEKTVLPRRFWLYALAAAFMAAGYIDYPLVAYHIQNHELADEMVIPLLYALAMGADAI
                     SAMVLGRLFDRGGAKVLLFVIIPAAFFPLLAFSDSMILIAAGMGLFGLGMGAQESVMR
                     AVVADLAPPGKRATAYGYYNTVFGMFWFIGSLGLGFLYDLSIPTMIAISVGLQLVSVP
                     LFLMFLRDKTV"
     gene            93984..94517
                     /locus_tag="PKM11_01500"
     CDS             93984..94517
                     /locus_tag="PKM11_01500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47219.1"
                     /translation="MPDIRDRVEDDRGLLKKIQMVVPGFRGYRIREDLRDSDRMLRVE
                     LAKRLGLQRSQLEDARRALVRENPMSKALEEMGGVVNTMKRVEGEILHAEVGYSGISA
                     DIKMKDDELNRLYEYDNSMIESLNFIDDALIKVPGMVRSGNDAGLRDAVDTVRTRVDG
                     LESRFKRRKAAITGTGL"
     gene            94522..95661
                     /locus_tag="PKM11_01505"
     CDS             94522..95661
                     /locus_tag="PKM11_01505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HNX47220.1"
                     /translation="MSLIGAETFNWEDGNKRNNIMYRMPRNIKFNDNIVVREDEIAVF
                     YRDGKALAYLDRPDRYALTSLNAPIIGKVIEALSGAKQQAEIVYLQKRAFDGKYGSKQ
                     PYQFRDAEFGMVNLRVFGEFRYKVGAPENFVNQFVGTFNFATSSDVEDRIKEQMVVLI
                     YNAIGEMKNKGMGVADLASQLMNIEQVVLAKAKDHFELYGVIIDKVSGMYVSLPDEVQ
                     KAVDMRASMQILNTNYATYQAGQAMREAASNPSGGAAAAGVGVGAGFGAGYMMVDAMR
                     QGGAAPAAGAPAAAPAAAPAAVAMVACSKCSTPNPVDGKFCRNCGNKMQNNTVKCSKC
                     GNEVPSDSKFCPECGQQLKGSKNCPKCNKESPMNAKFCPECGTSF"
     gene            95671..96414
                     /locus_tag="PKM11_01510"
     CDS             95671..96414
                     /locus_tag="PKM11_01510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47221.1"
                     /translation="MASMNCTKCGAPVEFDVGDKFVKCSYCSSQIFIDRSGAGFYYAL
                     PFSVQENDAVGTFRRWAGGSTRAKDLDKLAQIASLKKQYFPVYMFKRDVSGMEHIYIE
                     PAASTTLPGLHNLKVPGGDLKVFDERFDTSGAELIKIDIEMAPYLSSLPGAAKEQALV
                     YFPIWRLDYVFEQKNYVVIISASSGEVFSGEFPPRSSGAYMAVAGIGFVAFLAEGLLA
                     LFVPLLAIGLMAVTVVGVFAASNFVARRM"
     gene            96416..97420
                     /locus_tag="PKM11_01515"
     CDS             96416..97420
                     /locus_tag="PKM11_01515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47222.1"
                     /translation="MSISVGLNCPACGGAISISEGENVLNCNYCGSLLWAEGDAGVMT
                     VAFRNVQGRDSVLRATEEWWRKGLKARDLKTKGKLLECYPIYLPFWSTTTRIAGWICG
                     YEERRYTDRDGHTRTERIPKEEMVLHDYRYTNIACDPGDLGIKYLRNVNGEASFADFE
                     SIPTFESTTSKDDMVEMSKQNALNDARSDANVPHITFEKVTAIPKHISQIFYPVWVVR
                     YAYGERMYMATVDGVTGKVLSGRAPGDALYQSLAMTGGTSVGGLVAAGGLAIGLGMGE
                     GAVAIIGLVVGVVILGFTYRFFRHGSEITEGDFDDKRSTNLRKELKKGLNIDLGGFRI
                     "
     gene            97417..98004
                     /locus_tag="PKM11_01520"
     CDS             97417..98004
                     /locus_tag="PKM11_01520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47223.1"
                     /translation="MKVVQVKCPRCQQPIYSKVKDRAFYCGHCRTMHIRNGGPSIIDF
                     DIGEFNVNAPPDRIYMPFWRLFSTFSINESKVSGGTIHKLGRMIKGDAKGGNLFIYVP
                     GWETDVGTFKQWSMGLTENQPVYSLRPDFNNVERGATSVSKEEAMQMADFIIVTMEAE
                     RPGVLQYLDYGLQVHDARLVYLPFVRGPSGLAPGF"
     gene            98047..98595
                     /locus_tag="PKM11_01525"
     CDS             98047..98595
                     /locus_tag="PKM11_01525"
                     /inference="COORDINATES: protein motif:HMM:NF015944.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HNX47224.1"
                     /translation="MAELRLSKGMIAAIVAVVAVVIVLMMVALSYNGMISKQQGVENA
                     WGNIEARYQRRVELIPQLQSAMNLSIEFQASLYTNITEARTRWLSSIGNIPAQLNATE
                     VMDRNLAVLVATYENYPQLDLGVIQSFVAELSSTQGMIDAARIFYNDAVREYNTAIKK
                     FPNMMFAGAFGFEEAVYYSQGM"
     gene            98604..99341
                     /locus_tag="PKM11_01530"
     CDS             98604..99341
                     /locus_tag="PKM11_01530"
                     /inference="COORDINATES: protein motif:HMM:NF016424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HNX47225.1"
                     /translation="MRISRPIAITIVTLIVVSMLILAGFAIWKYFQPDPRFEGIPELD
                     YYVTDEVGVLYNYYEIEDICYTVDMNTSCEIAVLIVNSTLPRSANEFALRTFQMNEIG
                     KEGKDNGVLILIVTSTREWKVEVGYGLEGVITPTFLNQIATDYVIPYLEVDDYGEGAY
                     NMALFIGAEILDKYEGAESGDPAFPIHGIPLTITQWIIIIVILVALTAVTRGRIWYLL
                     FFILTFGRGGGGFGGGRSGGGGGGGRF"
     gene            99432..102308
                     /gene="leuS"
                     /locus_tag="PKM11_01535"
     CDS             99432..102308
                     /gene="leuS"
                     /locus_tag="PKM11_01535"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HNX47226.1"
                     /translation="MSLRSSEIETKWQERWYASRINEVEKDGRPKFMLIFAYPGVTGY
                     LHVGHMRGFTYVDAIARFKRLEGYNVMFPVGTHATGNGAISLAARIARKDQKTIDYLC
                     GNTCPINILDSLKDPVKVVEFFNEVYVNKYWKRFGFMCDWRRFTSTVRPDYQRFIQWQ
                     FRKLMQKGLLIQKPYYAPACVAHGPVAIDASETDIQCGGSAETVEYTLLKFKCGDMFL
                     MAATLRPETVFGQTNFWVNPNADYVKIKVNDETWVVSEDAYFKLTYQMENVERVASIK
                     GSELIGLKCLAPMVHREILTLPADFVDPNVGTGLVTSVPSDSPDDWISLRAIQQDEAT
                     LDRYGLDKDAVRAIRPIAIIEMKGWSDLPAVEVTERMGITAPGDPKLEDAKKLVYKDG
                     FHTGKMNATAGEFAGLPVMEAKERMKQLMLTSGEAAVMYDLSELVTCRCGERVVIKKV
                     TDQWFIDYANPEATAASKEHAKSMDIFPAEYYQNIHGVLDWFRERACVRQGNWIGTKF
                     PFDEKWIIEAISDSTLYPIYYTISKFANDGSIKAEQMSEEFFDLVILDKGDMATVSAS
                     TGIAQEVLKKIRDDVHYWYPLDLNLGGKEHLTVHFPAFLMNHVALLPKEMWPRGIFVN
                     WWVMGKGGKISKSKGGAQPIPGAAEEYGVDALRLYYAHIASPHADVDWDNEAVEGYTS
                     RTEKMERTLLDLMSLDGRESDVDGWMISRMASRVLRVKEMMRTYDLRSMANEVYFEAF
                     NDLRWYQRRGGCHAPTIKRVLDLLLPLMMPITPHTAEELWEAAGNKEMVSATLLPEVR
                     EGEIDVSKERAEDYLRSLMDDANEILKVTGMKQTKITFFTTAPWKREVVSMAMALQEK
                     GDLKVPTLTKMAMSDETVRSKGKEASDFARKTAEDLMKRSPAEVRKLAQRFDEISFLK
                     ASREFLEKEYGCAIEVHEAGEHDVADPQNKARQAAPWRPAILVE"
     gene            complement(102309..>102705)
                     /locus_tag="PKM11_01540"
     CDS             complement(102309..>102705)
                     /locus_tag="PKM11_01540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0006725 - cellular aromatic compound
                     metabolic process [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HNX47227.1"
                     /translation="LQLADEVYHEDELFAPVASGSHRFDAMIVCPCSESTLAKIASGI
                     ADNLVTRAAAVCMKERRKLIIVPRETPQSPIMLRNALRLAEDGAVIMPASPGFYPRPQ
                     TVEDLVNFLVGKILDQLGQPHELFKRWGD"
BASE COUNT        21820 a        29258 c        29597 g        22030 t
ORIGIN      
        1 tgttctgcac ttcccgaaaa ttgagcaagg acgtggccaa ggacctggac ctcgaccggg
       61 tcgtcgagct gatcctggag gcccaccgca aaggggaact gaaggcggtt gcgttaacat
      121 cggccgtggt cggctccatt cgggagacga tcgaccgcat gacgtacgtc gtcgacaagg
      181 tgcgccaggc gctcccggac gttccgatcg gggtcgaacc gtacgtcgag tccttcgagg
      241 acatcgaccg tctgcgcaac gccggcgcga acgagatcaa gatcaacata gaatcgttcg
      301 acccacgcat aatcgcgatc gcatgtccca agctggagct ggagaagcaa ttggagttcc
      361 tgcgatatgc cgtgcaggtc ttcggtcgcg gaaaggtaac ttccaacatc atcatcggtc
      421 tcggcgagac ggaccgcaac gttctggagg gcgtttccac actggcaagc ttaggtgtgg
      481 ttccatcgat ccgggctctc aagataaacc cgatgaacag ggtagtcatg gaggcggccc
      541 tgggcaaatt gaacccggtg acccccgaga ggcttctcca cctgaaccag gaagcaaagc
      601 tgatcctcat ggcccacggt ctcagcacta cttcgtacca caccatgtgc catgagtgcg
      661 gttgctgtga tatagtaccg ttcagggacc tctgattttt aggttgtctt tcttcttggt
      721 gctatggcta gatttaggta acttaaaatt tatatatttc tagttaggta accctaaatc
      781 atggtcagcg agaacatcga ggagtacttg gagtgcatct gggagctcac ccaggacggt
      841 actcccgccc ggaccaccga catcgccaag aagatgaagg tgtccccggc gagcgtaacg
      901 gagatgatgc agcgcctgga ctcgctcgga tatatcgttt acgagaagta caagggggtc
      961 acgctgaccg actccgggaa caagatcggg gagaccataa agcgcaagca ccgcctgcta
     1021 gagaggttcc tcgttgatgt tctgggcatc gccaacgaca agagccacga ggaagcgtgc
     1081 cgcctggagc acatgctatc cgacgagagc gagaggcgca tctcgaagat gatgaacaat
     1141 cccacgacgt gtccggacgg cgatccgatc cccgccctgg accagctctg ccttaacaag
     1201 gatgaagatt catcagtgct gagcgagctg tccgagggtg acgaggggat catctcccac
     1261 ctttcatgcg acgacccgca gaagatccgc cgggtgatcg ccatgggctt cgttccagag
     1321 cgttgcatca ccgttgaaga gaagcttccc ctgggcggac cggttctggt tcaagtagga
     1381 gattgccgcg tggcgttagc gaaggaatac tccgacctcg tcttcgtgaa caccaggaga
     1441 cactgccaga agcggcaccg acacggtggt aagtgatgga ggtcctgctc atcggaaatc
     1501 cgaacgtcgg taagagcgtg gtcttcaacc gcctcaccgg tgtcggcgcg atatcctcaa
     1561 attactcggg gacgaccgta gacttcctca aggctgacat gctggtgcac ggtaagaaga
     1621 tgaccttcat agacctgccc ggcatttact cgttgacgaa cggaacggag gaccagatgg
     1681 tggcggcgaa gatgctgcac tcggcgtccc cggattgcgt tctagtaata gcggacgcca
     1741 ctcgtcttga gccgtccctg gtcctcatct tccagcttat cgaactcggt tatccgatac
     1801 tcgtggccat gaacatgatg gacacggccc gcaagcgtgg cgagctggac gttgccaagc
     1861 tatctaagat actggacgtc cccatcgttc ccacggtggc cgtcaccggc gagggcatgg
     1921 aggagctatt gaaggccctg gatacctgcg cggcgcggcg ctccaacttc aaggtcagct
     1981 atgactcgca catcgaagcg tatctggagg tcatgaagct cagtatcgcc aaagccgagg
     2041 taaagtaccc cgcccgcggc gcttccatca agctcctgga gggggacgag gagttcaccg
     2101 aaggggtacc gaaggacctt cccatccagg tgcgaaagct gagggaggag ttccgcaagg
     2161 aacatgacga agatctagag gtccatgtca accgagaccg ctacggcgaa gcgggacgca
     2221 taatttccga ggtgtcaaga ccgaacgtcc agccacgtac gcgcggtcag aagctctccg
     2281 acctcaccat gagaccccgc acgggcatcc cgatactcct ggccgtgcta gccggcgtgc
     2341 tcatgaccat catcttcctg ggcagctggc tggaaggtac gttgctatcg ctctattccg
     2401 acctcgtggg aacgttcttc accgatctgg ccgattcaat cggcggcgag cttggtcagg
     2461 cgttggcctc cgggctggac ctcagcatcc aggccatact cgctatcgtc attccgtaca
     2521 tcctgctgtt ctacctgatc ctggcgttgc tggaagattc cggttacctg ccgcgggtgg
     2581 tggtgcttct cgacggcgtc atgcacaaga tcgggttgca cggccaggcc ataataccga
     2641 tgctggtggg catgggctgc agcgttccgg cgatccttgc cacaagagtt atcgaatccc
     2701 gccgcgagcg tctcatcctg ggcacgataa tcgtgatggc cattccctgc tcggcgcaga
     2761 tggcggtcat catcggcacc gtcggaaact acggcggcat cgtttacgtg ctggcgatac
     2821 tggccatact tctgggcctg gtgctgatac ttggacgact gctgcacaag gccatcaagt
     2881 tcgagccgac aagtctgatg atcgagatac ctgacctcag cgttcccaga ggaaacaaca
     2941 tcctcaggaa gacctgggtc cgcatcaagg agttcttcgt catcgccttc ccgatactgc
     3001 tcatcggttc catcgctctg gagctgctga acgcctacgg gatactggac cagctcgtgg
     3061 aaccgctagc cttcttcacc gagggctggt taggattacc ggccataatc atcatcgccc
     3121 tgatcttcgg cgtgctgcgc aaggagatgt cctaccagct gctgatcgtt ctcttcggaa
     3181 ctgcgaacct ggctacggtg atgaccgtcg agcagctgtt cgtgttcgct ttagtcatgg
     3241 ccaccttcat gccctgcatg tccgccttcg ccgtgatgct gaaggagtac ggtctgaagg
     3301 acacgcttct gatggccgct tcatccatcg tcctggcgtt cacgttagga ggcctagcga
     3361 acttcctgtt ccaggtgttc tagtaaaatg tttaagacga tagtcattac cggggacgga
     3421 tgtaccgcct gttcctggcc gccctggcgc tcagcctgat attctgcgcc acgccaggcg
     3481 ctgtgaacac tcaggcgctg cgggtcggcg tcaccggcgg ttttcgcaga gcgttcggcg
     3541 tggagatggg ctccatcgtc ggcgacatga gctgggcggt gctggcgttg gccggactcg
     3601 ccgtcatctg ggacaacgac atcgcgcgca tcgttctggc catagtcggc tcggcgttcc
     3661 tcatatatct ggcataccag ggcttccagg acgcccggag caaggagatc caggaggtga
     3721 acgctcctaa aggtcatact gacttcgtta cgggcgtgat aatgtccttc gccaacccct
     3781 ttcagatacc gttctggatc ggtatcggca gttccagcat agcggtcatt atgtccgacc
     3841 cggggctcat ggacttcgtg atgttctact tcggatatct ggtgggagcg gtgatctggg
     3901 gcacggcgta ctccgcgctc atcggtcacg gaaagcgcta catcacgccc acgcttttcc
     3961 gcattctgag cgtaatatgc gcggcggtgc tgctgtactt cgctgtgaac ttgctataca
     4021 gcacgttcct ctaatgcgtg aagtacgcca gtaatttcgg ggcgaccttc tcgaccttca
     4081 cgaagccgaa gcgttcgaac tgcacgacct tgccctcttc ctccttcggg atgttctcca
     4141 cgaaaccgtc cttgcgctcg cccgtgggca ttatgaccgt cgcgggagtg cagttgtccg
     4201 gcacccagtg gatgatgcgg catccttcct tgagaatgga gaggtcgttg cccagataga
     4261 gggccttacc ggagcggaat tcgacgttgc cgaggtcctt caggcggacc ttgccgacct
     4321 ccatcgccgt gttcaggtcc ttctccacca cgtgcacgat tatcggcgag ttcagctggt
     4381 attccctgat acctagttcg ggatggtccg gatgtcgcgg ggcgtgggag tgcagttcgt
     4441 tcacgccgca gatctgcaac ggcacggggt cccagacgaa gaagtagcgg ttggcggtct
     4501 tgtcgaccag ggctttgtta taagcgtaga tgttgtccca ggagaactcc acgtccgttt
     4561 ccttgatgcc gcaatcgacc cagtagttgc gtatggcctc cgggcggaac cctctcttcg
     4621 ctagcgcccg cacggttcct aaccgcacgt cgtcccagcc cgagtattcc ccggacttga
     4681 tgccttttcc gaccgttgac gtcttcagga tggcgtccgg aacggagacc agaccataat
     4741 gggtgtaatg cgggaccttc cagccgaaat agtcgaaaag gtacgcctga cgctgagtgt
     4801 tgttcaggtg gtcctttcct ctcaggacat gagtaagacc gaggaaatga tcgtcaatcg
     4861 ccacgctgaa gttcatcatc ggatagacgc agtacttgtc gcccttcagc ggatgtagcg
     4921 tggacttgac gatgcgcagt ccgacgaaat cccttatggc cgggttcgga tgcttgaggt
     4981 cggtcttgac cacgaagacg gctttttcct cttcgtaatc gccggccagc atcttctcga
     5041 acttgtccat ggtcgtggcg atatcctcat catgatgcgg gcagggctgg cacttctcct
     5101 tcaatgccct ccattcctcc accgggcagg tgcagacgta ggccttcccc atctcgatga
     5161 gcttcctcgc cacatcgtaa tagatctcga aacgatccga ttggacgacc gtctgatgta
     5221 ccttgacccc cagccaatcc aagtcctccg ggatcatgtc gtaggcgttc gggtctatct
     5281 tgtccgggtt ggtgtcctcc atgcggttga tgaacttgcc gtcgtagttg cggcagtaat
     5341 cgtcattgag tatcgccacg cgggtgtgtc ccaagtgcaa gggaccggac gggccggggg
     5401 cgaagcgcat cacgaccttg ccgcgctcca tgtccggaag ttccggcagg ccgacgcgac
     5461 gctcggtctt ctccctcttc agcatggtga cgtcgatgtc ctccagcatc ttgtgctgga
     5521 cctccggcgc cagggcgttc acctcttcca ctatggcggc gatgagcggt aatacctcct
     5581 tgacccgggt gcgcatctcg ggcgattcgg ccagcacctt gccttgcacc gccttgggat
     5641 tggccttgcc tgagtagagc acggcgttct gcagagcgta cttccgaatg gtcgcttcca
     5701 ggtcctcgga catcgttccg cgatatcccc ctccggcttt ttaactttcg tagccacgga
     5761 aggaaatcgg ttatatgctg ggacggtaat tatcgctcat ggccgtgcaa agccacctgg
     5821 accgcatgaa gggagtcaag gtcatcgaga aaaaggtgcc gatcgagatc gagccgacgc
     5881 gcatcctgat ggccgatcag cggtcgccag ttctgttcaa cgacctcaat ggcatgaagg
     5941 ccgccgggaa cctgtggagc gagagggagc gcatcaccga ggcgttggga ttgccgaagg
     6001 acggtctcac ccaggcgctg atgcaggcgc tggcgaatcc gagaccggtc gaggaagtga
     6061 agaaggccaa gttcgaagag atcgtggagg agaagttcga cctccgcaag cttcccattc
     6121 ccaagtacta ccctcaggac ggcgggcagt acgtcaccgc tggagtggcc atagccgagt
     6181 tcaacggcaa gatcaacgtc tccttccacc gcctgatggt catcggcaag gacaagttcg
     6241 ccatccgtct cgtgcccagg cacctgttca ccatgcacaa actggccatg gagaaagggg
     6301 aggatctcaa ggtcgccttc gtggtcggta cgtgtccatc cgtactattg gcgggcgcca
     6361 cgtccgccga ttatgagttc aacgagctgg agatggccag cgctttacgc tacataggtc
     6421 tcaaggaggg gctgaaggta cgtcgcacca agtacggcat cccggtgccg gcggacgcgg
     6481 attacgttct ggaagggcgt ctcacgtcgg aaactgccga tgaaggtccg ttcgttgata
     6541 ttacgggcac ttacgacacg gtacgcaagc agccggtgtt cgtcgtcgac cgtctatacc
     6601 gccgcaagga cgcggtgttc caattggtcc tttccggtgg gatcgaacat ttcctgttga
     6661 tgggccttcc gcgtgagccg gtcatcttcc gtacggtacg acaagcggtg cccagagtgc
     6721 acgccgtccg tctcacggaa ggaagctgct gctggctgca cggtgtcgtt tcgatcacca
     6781 agaacaagga aggcgatgcg atgaacgccg ccctggccgc cttcaccggg cacccgtcca
     6841 tgaagcaggt gatcatcgtc gacaaggacg ttgatatctt cgatgacaag gcggtggaat
     6901 gggcggtggc cacacgcttc caggcgtccc gcggccttct ggtcatcaac aacgccgccg
     6961 gttcctcact ggacccgagc actgaaggga caacctcaaa gatcgccatt gacgctacga
     7021 tgcccatcgg ggacgtcaaa ctgttcgaga aggcggcgct agataagaaa tgatgaaggg
     7081 cagatcgcga gacctatcga taggcacttg atctaggtgt tgtactcgat gcgcggtcaa
     7141 taaaggtctt gatggaataa atcattaata atccagacct ccttttccct tcaaatacgg
     7201 aggatctccc ttgagatgca ataattgtgg attggattac atcgcggaca acgccgccgc
     7261 ctgcccaagg tgcaatgcgc ccctgcagat ggggtatcag cagccgcctc agcagtacca
     7321 gcagcccccg cagcagcagg gttaccagga acagccgcct cagcagtacc agcagccccc
     7381 gcagcaatac ggggaccagc agtaccagca gcagcctcag ggagcacagc agcccccgca
     7441 gggcggatac tacgcccctc cgcaaggggg ttactaccag cagccgccga tgccgccgaa
     7501 gcgcgtgcca acggtgaaga gggtcgacct cactgagata ctgatggtcg tctctggact
     7561 gttcttattc gtcggagcct tcggcaactt cagacaggta gcaacgttat cccagatcaa
     7621 tgttgatatc ccagcgggga tagtgatcct gggtatagtc tgtctggtgg gcgccctgct
     7681 cctgttcgtg gacgtgctca tgcccgccct gctgaagcag ctcggtgaga tcaaggacat
     7741 actggtgctc gtgctcgccc tggtgttcat catctggggt ctaataactg tctttgcgga
     7801 cacctctaag tacggcatct acgggcctga tatattcacc ggtggattcg ccctgctcgc
     7861 cgctggcgcg ctgcgcatgg gcgttctgaa gtgaacgacc aaaacctctt ctttcaaact
     7921 tttttgaggt tttctttttt cttggattac agttagtgcc agttattaat tagacctgtt
     7981 ctcgtatcat aatcaggcaa gaaaatggct acctcttcct tcgaaagacc gtttaagata
     8041 caggacgatg acgcagccaa ggccatgctc gatgccatgg acaatcctac agccgatgat
     8101 catattcata aaagtaattt tgaagctgac ctgagaaggg gactggaact attgaaaaaa
     8161 ttgtgatccc cttaaaggca attctatcat taaaacccga agaggaagtt acgatccttc
     8221 tgggtggatt cagatgtagc gctatcaccg tgacggctcg ggatctcacg ctcatctaag
     8281 aacgctgtaa gtgacaaata cagcggtcat gccggtcagg gggccgacat caccgtctta
     8341 tggtgtcttc ccggcccttg ccgatgctga tgatcttggc cggaaccttg gagcgcttct
     8401 ctatgtaccc gatgtagtcc cgcatctcct tcggtagcgc ttcgtagccg ccgcggacta
     8461 tttccttggt ctcctccggc ttccagccct tccagccatc tagctcctcg tagaccggct
     8521 tcgcccgctc cagcatcttg aagttacccg ggaagtgatg gaccttcttg ccgtctatct
     8581 cgtaagcgac ggcgaccttc accttcttca tgtcgttcat gacgtccagc ttcgtcaccg
     8641 cgaactgcgt cagtccgttc aaacgagcgg cgtgctccac gactagcaga tcaagccatc
     8701 cgcaacgcct ggggcgcccg gtggtggtac cgaactcgcc gccgacgttc atcagcatat
     8761 ccccggtggc gtccttgagc tcggtgggga acggcccggc gcctacgcgg gtggtgtacg
     8821 cctttagtac tcccattatc tcgtccacgc gcttgggccc gaccccggaa ccggtgcata
     8881 tcgctcccgc gacgcagttc gatgaggtga cgaacgggta agttccgtga tcgatgtcca
     8941 gcatggttcc ctgcgcaccc tcgaacagga cgttcttacc ctggtccaga gcgtcgttca
     9001 ccaggacgga cgtatcggtg atgaagctct cgtacttgcg accataggcc agtaggtcct
     9061 tgaaaagctc ctcctggttc tgggccaggc ggacgccgag tatctccatg accttgagct
     9121 tcatgggcat gacggtgtcg agacgctcct gtagaagttc agggtccagc agatcgccca
     9181 ttctaatgcc ggagcgggct atcttatcgg agtagcaagg accgataccc tttcctgtcg
     9241 ttccgacggt cttctttccg cgcagccgtt cctcggcccc gtccaaaagg cggtgccaat
     9301 tgagaatgac gttcgcccgg tcggagatct tcagtccggc gacggagcgt ccgcgcgatt
     9361 ccacttcggc cacctcgcgg tccagagaga gcaggtccac gatgaccccg ttcccgatga
     9421 cgttgatgac attgttacgg acaattccag aaggcagaat gtgcagggcg aagacctcct
     9481 cgcccacctt gatggtgtgg ccggcgttgg aaccgccctg gtagcgaacg accatgtcgg
     9541 cgcgtccagc ctcgtaatca gtgatcttgc ccttaccctc gtctccccat tgagcaccga
     9601 tgaccgctat gcttggcaaa ctctcaccgc ctctcaaaat gagccaacgt agataaagcc
     9661 ttgttcaccg gccgatggaa cggaaggctt ccagcacttc ctccaatggt cggtcagttc
     9721 ggaagccagt tggcgaaaaa ttggttctgg acacctttcc gatggagcgc atggcctcca
     9781 gcagctcgtc ccgtcccggg ggtgaaagct tgagcatggc ggccagctcg ttcgtttcgt
     9841 agtagtaggg aacatccagc tcctccttcc agatatcgaa gtgctgacga acgcgctcct
     9901 gacattccaa tccttccgga acgatggcgt tcgagatctc ctcatggtcc atcagcgggc
     9961 cgagccagag cggaccgatc ttcccctcgc cgacctttcg ttcaccgctc tcccggtcat
    10021 aggacatcat tcccaactgg gcgagggatg tgtcggcggc gccggcaccg tccttggtcc
    10081 tgaggaacag gcggaagtaa tggtcggcgt agtagcacag cagaggcgtc acgcccttgt
    10141 cctcctgggc cgccatgcgc acgatggtgc ctatcatgat acgaaggccg ctctcgtgca
    10201 ggaacgggtt cctctggctg ttggccatgt accgtctccg gcacttgccg ggatgcgttc
    10261 cggagagcga cgcggtatcc gtcgccgtaa gcgccagtat tcccttccgg gacatgccct
    10321 gcagggccga cggaacgaac ggtatcggcg tgccgaacgg atcaaggtcg atgtaatcga
    10381 acttctcttc ggccagaagg caacgcaggt cggcgttgca cacctcggcg ttctccagag
    10441 agttaagctc gatgttcctc tggatgtgat cgcaggccag cgcgtccttg tcgttaatga
    10501 cgaagcggtg gtttcccggt gcttcgttac agattcgtat cccgcgggcc ccggtggcgg
    10561 ccatggcgtc caagcatttc cgaggtctga tgaccgaatg gaacagcgcc acggaaacgt
    10621 cacgattgaa ggccatctgc cggttgaaga agacccttcc ctcgatcttg ccggggcccc
    10681 tttcggatat ggcctcggga acgaatagct gggtgctccc ctctttgatg atatttcctt
    10741 ccaggttcac aaaagctcgc ccttcatcag cttcattatc ttgtagggca aaaggtttct
    10801 gtttattgga gttacttcca atatacgaac gtcatcccgc cttctgatgt cctgcaacag
    10861 gggattgcgg gacttcttgt gcaaggtcag gagcatcggc ttttcctttt tcaacgcctc
    10921 tttaacagcg tcacggaact tgtcgctctc cacctcgatc ttgcctactt cgtcgatgac
    10981 gatgacgtcg gcgctctcgc aggcgttgac cagggcctga acgccgatct cctggagaac
    11041 ctccaggtca acgcccatct tgcccaccat gaacttgctg tgaatatcgg tagcggccag
    11101 taccccacgc ttcttggtca tccagtccat gacgtagaga ccattgcgct tcttgtcgtc
    11161 caagatcggc tcggtgatca tgcccccgac tataagccca tcttcctcga gcatctttat
    11221 gacctggatg agggtgttgg tcttgcccgc gctaggaagt cccgtaatgc cgatcttgat
    11281 gttattcatc caattccccg aggtcaacgc atcgaatggc ctcgatgctt tgagagacct
    11341 atatggaaat cctagcttaa tatcctttcc cgagaaacag aatgctgggt tcgccctggt
    11401 aaacttttat aaaaataata atggccgtat ttatcggctc tcgaccgacc tgacgtacat
    11461 gagcgggtaa cgcaggtcct ccttgaagtc catggccgcc accacggtgg tcccaccgac
    11521 gttaatggtc agttccacgt taagcatgat gcccgtcagc gtctgatagt cgaactcgtc
    11581 cttctttcgt cggagcgcat cgcgagagat atgcaccttt acgtccttta cgaacggttg
    11641 cacgcgcacg ccatcctcta tggccttttc cagtatctcc acgttagctg cagcaaccgg
    11701 cgttcccacg aactggtgat agatcgttcc tagtttgatc cccgcctcga acaccgccct
    11761 ttcctgttcg ctgcagttga agtaattggc agcgagctcc tcgcgcttgc tagtcatgac
    11821 gttgatgata aggcggacct gattaataat tcctgtcctg gcctgaacta tttcccaagg
    11881 accggcgaaa aggatatacg gtcgacggcg gttcgaccac cggggccata acgcatgttt
    11941 gagaatatca gactaaggct taagatggac aacgagccga aggagagcat cgatccccgc
    12001 gcccgcaagg tgtggatgat cggcggagct ctaggttcga tcgtgatcat cgccttggcc
    12061 gtgggattct atttcctggc cacaataggc ttcgaggccc cgcaatgggt gggatggacc
    12121 gccatcgcct tggcgctcat ctacgttccc tggggcgtgt actttcaccc ctggctcagg
    12181 atccgcttct ggcgctacga gctgcgggcc aatgagctgg agatccagca cgggatattc
    12241 gtgatcaaga ggcacctcat ccccatggtc cgcgtccagt acgtggatac ggaacacggt
    12301 ccgctgatgc gctacttcgg tctcaccacc ttatccatat ccactgccgc caccaagttc
    12361 gccatacccg ccctaccgaa gcagagggcg gaggagctgc gcggcgagat cgccaccctg
    12421 gccagggtca gtgaggaaga tgtctgaatt ccgccgccag catcccctgc tcatacttct
    12481 ggacaccggg cggggtataa tctcgaacct gagcttcgcg ctcatcatag cgatttcact
    12541 gccggacgac atattcggcg ggttcatcgg caatgccgta gtggccttgc tggccatgtt
    12601 cggtctttcg gctttgttca acgtcctgcg ttggtacttc ttcgtctata gttacgagga
    12661 gggcatggtg cacatccgtc agggagtgct cttcaagcgt gagcggacca tcaagaggga
    12721 ccgcgtgcaa tccatgaaca ccaatgccaa cgttctgcag caggcgttcg gtctggtgac
    12781 actacagatt aagaccgccg gggtcaacgt cgacgccgag gtcaatctgc gcgcggtatc
    12841 gaagggcgaa gcggagatca tcaaggagcg tctctactcc aagagcgccc gatcggaatc
    12901 agaaccggtg gaggttccga gggcgttccg cttcctgcaa ggccgggaca tctggcttgc
    12961 cgcgctcacc tcgggaaggt tcatggtgct cttctccgtg atcgccgtga tatacgccca
    13021 gaccttcgag tacatcccgg agagctactg ggaatgggcg gtggagagcc tctcggccat
    13081 tccactgatg gccggcatcg gtatcgtact gggtctgttc tttctgacct gggcgctctc
    13141 cgcggtggcc ttcgtcatcc agttcgccaa cttctccgta cgccgtttcg aggaccgtct
    13201 ggagataacc tggggcgtgc tgaagaagaa ccacgtggtc gtgaagctgc accgcgtcca
    13261 ggcggtggtc gttcagcaag gtccgctccg gcaaccgttc ggcctatgca cgatgttgat
    13321 cgaggtggct gggggcgggg cgaaggagca ggagaggata tccctgctgc acccgctcgt
    13381 ccgcagaagg gaggtcgaag cgttcctcgc cgacatcctg cctgaatacc atttgcccct
    13441 cgtcacgctc gcccttccga agcgcgcatt gcgccgctac ctgttccgct cgatcgtacc
    13501 ggtggcagtg ctcatagcga tggtcatcac tgccttccac ttctgggaac ttccctattc
    13561 ctgggtctcg ctcatcctgc tggtcccggc ggttttgctc ggcttttcca gataccggaa
    13621 cggctccata tccgtggagg aggaccagct gtccctccgc ttccgttact tcagtcgggt
    13681 gcaggtcctg atcaaacgct cgcacgtcca gtcgatgacg ctaaaggcca atccgttcca
    13741 gcgcatggca aagctgcgca ccgtgcaatc gtacttcctc tcctccccgg cgggaaagag
    13801 ctatcatacc agggatttgg acgccaagga cgcccagacc gtatgggaat ggtactcgcg
    13861 gaactaggct tcggtgcgga acgcttcctc tttctggaga ggacaaccaa aatcattatc
    13921 cacttcaagc tccgatagct tcggtcaggt aataacatgg agcaagccaa gagatacgag
    13981 ctgcccaagc tcgcttacgg atacaaggac ctcgccccct tcctgagcga ggagcagttg
    14041 accgtccacc acaccaagca ccacgcggcg tacgttaacg cggccaacgc catattggac
    14101 aagatggaca aggcccgggc ggagaacgcc gacctggaca tgaagggaat gctgaaggac
    14161 ctctccttcc agatcggagg gcattacctg cactccgtct actgggagac tttgtgtccg
    14221 gtaggaaagg gcggagagcc gaagggcaag ttgaaggccg agctggaaaa ggagttcggt
    14281 tccatcgagc gcttcaagaa ggagttcact gccgcagccg ccagcgccga aggttccggt
    14341 tgggccgtgc tggtctactg catgggtctg aagaagccga tcatcatgca ggtggagaag
    14401 cacaacgtga acgtcatacc gggattccgg gtgctgatgt cattggacgt atgggagcat
    14461 gcgtactaca tcgactacaa gaacctcagg ccaaagtaca tcgaggcctt ctggaaccag
    14521 gtcaactggg acgccgtcag caagaagctg gacgccatcc tgggctgaac aaacccttta
    14581 aaacatcgcg gtgcgcaggt tcctggcggg agcttgccac cgcaagttct tcttttagcc
    14641 atcccagcat atgaaggatt cctggctggt caagtaaata tttatacgga tttcggcatg
    14701 agttggccaa atgaacgccg cggagcgtat ccaggagctc aaggcgcaac gcaaggcggt
    14761 catcctggcg cataattacc aatcgccgga ggtgcaggat gtcgccgatt acgtaggcga
    14821 ttccctaggg ctttcccaaa aggcagccag cactgacgcc gaggtcatca tattctgcgg
    14881 tgtcgatttc atggccgaga gcgccaagat cctctctccg aacaagaagg tcatcctacc
    14941 cgaatcggac gccatgtgcc ccatgtcggc catgtgcacc gacctggagc tggccccggt
    15001 gaaagagaag tatccagagg cggccatagt cgcttacgtc aacacgtccg ctgccgtcaa
    15061 ggccttggcg gacgtatgct gcacttcagc gaacgcagtt aaggtcgtcg gcaagatgcc
    15121 gcagaagcgc atcatcttcg tgccggaccg gaacttaggc gcttacgtac aaaggttcca
    15181 tccggacaag gagatcctac tctggcccgg tttctgcccc acccatcatg acatggacgt
    15241 tcaggacctg aaggagctga agaagaagca tcccaaggcc aagctcatgg tgcatcccga
    15301 gtgcacgccc gaggtcatcg atctagcgga taacgtttcc tccacggaag gcatgatcaa
    15361 gtacgccaaa ggttccgacg cgcaggagtt catcgtcgga accgaggtgg acatgaccta
    15421 ccgcttgggc aaggaggttc ccggcaagac cttcattccc gtcccgacgg cggtgtgtcc
    15481 gaacatgaag cgcaccacca tctcctcttt gatcaaggcg ctggagaccc tctccccgga
    15541 gatcacattg gccccggaga tcatcgaggc cgcccgcaaa ccgttggaac gaatgatgga
    15601 gataggccgc ggggactgaa cctcttattt ttttacagaa gcgtctgcag cgcgtcgaag
    15661 acgaagagga ttgcgaaaac taccataagc actccggaac cggctatcac ccgctgatgc
    15721 caggaggcgc tccattttcc tttggtcccg aatatggtca ttcccacgaa cccttcccaa
    15781 aggagatcgc aggttatgtg caccaccacg aagaacggca gcatccacca tccgaacgtc
    15841 acggccgtgg ccgtcagggc cgctccgacc gtggcccacc acagcagcca gccgggattg
    15901 aaggccgtgg tggtgacccc cgcccagaag gggtcctggt gcttggtggg gcagctggtg
    15961 accacctcct tccgggtccg gaccacatcg taacccatgt aaagcaggat agccccgcct
    16021 agaaggccga tggcggcgag caccatatcg ttcttgagga acacgctaag cccgaagaat
    16081 atcgcggcaa tcgtgggcac ctcgaccaac gaatggccga gggcgatctt ccagccggac
    16141 catcggtcct ggaagccgca agcgatggtc acggcgaaca ccggaccggg catcagcacg
    16201 ccggagagcg agatgatggc cacggaacct aggaagagca gggcggagtc caagtcatcg
    16261 cctcacagat accagtcgac ggtaaggttg atatatactt cggggggcag gttgcgcagc
    16321 gtaccgctct ccacctcgat tatggagacg ctgtggatgt gggagttcat gatctcgttc
    16381 atgctgaccg gcgggctctt gtagtacagg tcgcagtagt gcttgaccac ccaggcctcc
    16441 ttctcgtccc tgtccctggt gggaagggtg aagaagggca tcaccggcat gacgtaatgc
    16501 ggcggcgcgg ccagcatgaa cttctggcag tgattgctat agcgggcgat cttggaggct
    16561 atcctggccc ggatgtaatc catgggatct aaggcatggg ccggcggaac gtaaccggtc
    16621 tccacttcca cgatcatgat gttgccgtcc ttctccgcgt aaacatcgca gctgaggccg
    16681 gcgtctatca tatgctccag gtccacctcg taaccatcct ctatgaggta cttggcgacc
    16741 accatctcca gcaccgaatg gttgatcttc aggaggttct tctccttgag gtccagcaat
    16801 cgctggtata ggttacgcaa cgactcctca caatgcgggt cgcagccggc caccagcttg
    16861 tcgatcaacg attccaggtc ctgggcgaac ttgtccaaaa gggtgcctct gtctcggtaa
    16921 gcgtgaacct aatccttaca atttatgctc cgtgcaattc gtgatgagca tgaaactaac
    16981 gtacaggggg gccgggtggt gctctctatc atcaagaaat gaagatggtc ctgaacgaag
    17041 gtcaataccg tctgatgaag aacgtcgacg gcaggatcat ggcgttcagt cctccgcgga
    17101 gggggagaac acgtcggtta tggtcccggt ctcgcaggat acgcagaagc cgtatccctc
    17161 cgaggttatc tcgtgggcca cgcgcaggga gtacggtacc cctacaaagc tcgtcttcgc
    17221 gtcttccaat cccatttgct ccatgttata cctcttttag ggaattgatg attattgcga
    17281 gacggcacat aaccgtgatg ttccggatct cgcaaggtta acgggactat gtctagaatt
    17341 ggacatgaac gaggggagca aacgtttaat tcgtgccatc aggtaaccag ggacatcatt
    17401 ggaccatata tcggatcgat gaagagaaac ggacgctgat cctcacggag atgatgagcc
    17461 ctatgagtgc agagatccag gtccaatgct cagtccagcc ggcgtatggt gatgtgcagg
    17521 ccaggcgacc gatcgcattc tccgtagcat ttgctggcgg ttatccgcac cacctgtgaa
    17581 tcgtccggga tgaggacgtt ggttattccg tccagcaccg cccttaccag cttgtccagg
    17641 tcggggcgct tggtgttcat cttccagcgc ttcggggtgc tcttcggccg ggtgaagacg
    17701 aactccatca gcacctcgta acccaggcga cggtcctcgg agaagtagct ctgcggcctc
    17761 agctggttgg cgtgctgcgc ctctgtggcg atgcggtgac gccacgcttc ggtgttggcg
    17821 ttggtgtggg tggtcaccac tcgctccagc ttcttgatgt agaaggcctt ggtcgaaccc
    17881 tgcggaactg gttccccggc cacgaagaac acgatgacat cgggatcgag ttcctcgtcg
    17941 gtcatgaagt ccaccggacc cgcctcatgc tcctcagcgt ccgcttcatg atcgttcacg
    18001 tgcatcccag aggggatatg aataccacgg gtcttataat ttcacccgcc gaacgccggc
    18061 tcagggtacc agccggttgc ggtccctggg gaacaatatg gtctcccgga tgttgttcag
    18121 gccgagcatc ttctgtacca tgcgttccac gcccagtccc catcctccat gcgacggcat
    18181 gccgtaagcg aaggcgttca ggtagaactc gaaggacttc gggtcgagcc ccatcttctc
    18241 catcctctgc accaggcggt cgtagcggtg ctcgcgctgc ccgccggagg atatctcctg
    18301 gcccttgtag tccaggtcga acgagtacga gtacggggta ccgtccttct ccatgatgta
    18361 gaacggcttc gccgcctccg ggtactcggc tatccagtac atctcgtatc cgtcctgggc
    18421 catcagatcg cccaggagct tctccccttc cgtgcccagg tcctcgccca gctcgatctt
    18481 gaatcccgcg ccctggacca tccctatggc cttctcgtag gagatgaccg gatacggcgc
    18541 tttggggacc acgacatcaa cgcccagtac ctccaaggcc cacttcccgc gctccttgac
    18601 ctcggagatc acgaactgcg tgcatccctc gatcatggcc atgacatcgc tctgcgaatc
    18661 gatgtgggcc atctccccgt cgaaggagac gaactccgag acgtgacgcg cggtatcgga
    18721 cggctcggcg cggaacgccg gaccgatctc gaacacccgg tccagtccgg tggacatcag
    18781 catctgcttg tagagctgcg gagattgcgc aagataggcc tgctttccga agtagtccac
    18841 cttgaacagg gtggagccgc cctcggcgcc ggacgctacc agcttagggg tgaatatctc
    18901 aatgaaatcg ttatcggcca ggtactcgtc gatgagccgc atggtcaggg acttgatctc
    18961 gaacaccgcg cgaacctcgg gtttccggag gtccatgtag cggtggttga accgcgtttc
    19021 catctccacg tccaccttat cgacgacgcc catcgggagc ggtgtctgcg cgaccccggt
    19081 gacgatcagt gaggaaggta tgatctcgta accggccttc acctgggcgc tctgcttgac
    19141 cgtaccggtc acccgcacca cggactccct ggccagtgaa gttatggtct gcatgacctc
    19201 cggtgcgatc ttcttcttgg gggcggtgat ctgaaccacg ccgtggcggt cccgcaagat
    19261 aaggaacgag atgccaccca ggttgcgtat ctcctgggcc cagccctcga cggtgacttc
    19321 cttgtcgtac tcgttggcgg ttatggaacg cgaatcgtga agcatgatga ctcctcgttg
    19381 gaaacatctc gacatctacg atttggctta taagcgttgg cggtccaggc attcgttcgt
    19441 tgacatttgc cggcaaagcg aaaaattaat gatgtccggg cagcgtgaat atatgcatgc
    19501 ctgttgaagt caggatagac cagaacgcgt gcaccggttg cggcatctgc tacaacgatg
    19561 aatgcccgga tttcttcatg gaaggggacg atgggaattc gaacgtgaaa ccgctatacc
    19621 agaaagggga caggtccatc ggtgaggcgc cggacagcct gattaactgt gtcaagaacg
    19681 ccgaagcgtc ctgtcccgcg tcagcgatat ccgtgaagta ggccatcctg gcccttccct
    19741 tatttttatc acggactagt catttggcga tacccgttcg tcaaacatta tatatcccag
    19801 cagtaattct gagagtccaa ggtatgggat tctaatgtct cagaaggtca ctgtctctgt
    19861 cattaaagct gatgtaggat cggtcgctgg gcactccaag ccgcacccga agatgatgcg
    19921 caagtgcgaa gaggtgctgg tccagggagt caagtccggg gtcatcaacg acttctacgt
    19981 aacccgggtc ggcgacgaca tcaacctgtt catgacccac ttcaagggcg agaaccacaa
    20041 ggacgttcac ggcctggcgt gggaagcgtt ccaggaggcc gccaaactgg ccaaggagat
    20101 gaagatgtac gccgccggac aggacattct gtccgacgct ttcagcggca acatccgcgg
    20161 catgggtccc ggggcggccg aggtcgagtt cgtggagcgg ggcgccgagc ccatggtgtt
    20221 cttcatggcc gacaagaccg agccttccgc atactccatg cctctctccc gcatattcat
    20281 ggaccccttc accaccaccg gtctggtcat agaccccagg gcgcacgagg gattccgctt
    20341 cgagatcgtg gacgtcatgg actccaagaa gatcgtgatg tccgctcccg aggaaacgta
    20401 cgatattctg agcttgatcg gcgataccac ccgctacgcc atcaagaggg tcatgagcaa
    20461 ggacaagaac ctcgggaccg cctgcgtggt cagcaccgag aagctcaaca tctgcgccgg
    20521 caagtacgtc ggcaaggacg accccgtcgc cgtagtaagg tgccagagcg gactgcccgc
    20581 cgtcggcgag gtactgcagc cgttcatgtt cccggcgctg gtcgccggct ggatgcgcgg
    20641 ttctcattac ggcgctctct atccctgctc cgttgaggat tccgatccga cctacttcga
    20701 cggtccgccg cggatctgcg ctctagggtt ccagatcagc aacggccgct tccagggttg
    20761 cgaggacccc gatgcgccgc tcggcaagaa gataccggtg gactacttct ccggaagcgt
    20821 ttgggacgag gcccggagga aggcggttcg cgccagcatc tacatgcgcc agcacggccc
    20881 gttcatgcct tccattcttg gacctgaaga gatggagtac accacccgtc cggccgtcct
    20941 cggcaagctg aaggacagga tggagaagat tgactgatct taggaccccg gtcataatcg
    21001 tcaacttcaa ggtctactcc gaggtggagg gacctggggc agttcgactg gccaaggact
    21061 gtgagtccgt ggccttggtc aaaaaggcca acatagtcgt ctgccccccg atggtcgagc
    21121 tttccaaggt ggcctccgcg gtcaccattc cggttttttc tcagcatgtt gataacaggt
    21181 cccccggctc tataaccggt ttcgtttcgc cgcagagcgt aagatccgcc ggggccgccg
    21241 gaacgctcat caaccatgcc gagcaccgca tgcccccgca ggacatcgtg gcagcgatcg
    21301 attcgtgcag gaagctaggg ttgatcagcg tggtctgcac cgataccgcc gagacgtccg
    21361 ccgccatggc cgccttctcc cccgacttca tcgccgtgga acctccggag cttatcgggg
    21421 gggacatctc ggtcaccacg gccgacccga ccatcgtctc acgcaccgtg gagatggtga
    21481 aggccgtcga tcccaaggtc aaggtgctgt gcggagccgg tgtcaagaac ggcaaggacg
    21541 tccgggccgc tctggaccta ggggcctccg gcgtacttct ggcgtccggt gtggtcaagg
    21601 ccaaggacgt caaggcggct ttgcaggacc tggtctccgc gctctgaagc ctgattgcat
    21661 cggataaccg tttttcctct tcgtccgttg ctcaagcgtg cgctttattc cgacggcaat
    21721 attggtggtg attctcttcc ttatcatctc cgcgatgccc gtgcaggctt cggatgctga
    21781 gagctcggat ggattgctca tctcccgggt ctgcgcgtcc tatccgggtg agttcatatc
    21841 gctgaccaat cacgggcctt ccctggatgt cctgggctgg cggataagcg acggggaggg
    21901 cagcgtgacc ttcagtaggt ccttgatcat cacgaccggt ggcagtgtca cctggagcgc
    21961 ccccggctcg ttcttcccgg agctgtatgc ggaagaggac tgcttctcga acgatggggc
    22021 atcggtcatc cttaagggca gcctcaagct cgctgacgcc ggagaccagg tatatctctt
    22081 cgatgctggc ggcgccttga gggatatggt ctgcttcggc aacgtcgagc cgaacccccc
    22141 ctggacagga ccgccggcgg tgctcaagaa aggcagtgtc atcgtccgaa ccgccaccgg
    22201 gaacggtcct gggaactggg atatgatggt ccccggcctg ttctccttgt cctctccctt
    22261 gttcccggcc gatgtcgttc cactcctcta tccagatgac gctttgccag aacttgtgcg
    22321 gcagatcgac atttcccacg aaagcatcca gctggcctgc tatctcatgg agaactggac
    22381 cttggccaga catctggccg gggcctccgc tcgcggtctt aacgtcacgg tgctgttgga
    22441 aggaaggccg gtgggcgggg tgtccgagaa cggtgcggcc ctggcctact atctgcagga
    22501 ttccggtgtg aacgtatgga ccatgcgctc gggcgaatcg ttccgtcggt acgactatct
    22561 gcacgccaag tatgccatct tcgatcggga acgtctgttc gtcgcctcgg agaacatggc
    22621 cgattccagc ttcaacagca atcgcggatg ggcagccgtc ataatgggga gccagataag
    22681 ctcgtttgct gaggacgtct tcctcaagga catttccgcc aaaggggtcg acatcttccc
    22741 tttgagcgcc actctggtcc gggccgacgg gggtccagga cgattgttga gcacggtgcc
    22801 cgcacctccg cgagaatatt ccgcgatggt ctccctggtc acctcgccct tcaatataca
    22861 ggaccgtctg gtagagatga tatcggcggc gcaggagcgc gtgctggtgc aacagatgcg
    22921 catcgacgag gattggatcg acgactccaa gatcatgtcc gtcctgagcg gagcggccga
    22981 acggggagtg agcgtacgta tccatttaga tgccggtctc ggcaccgaga aggggaacaa
    23041 gatggtggcc gaggccctca atcggaaggc gaaggataac gattgggacc tggagtgcca
    23101 tctgacggac gagatatcct ccttcggtag gctgcacaac aagggtgtga tcgtcgacga
    23161 tacggtggtg gtgggaagcg ccaactgggt ggacggctcg atgcagcgca accgggagat
    23221 ggcggtcgta cttcgttccg cggacctggc taacgttttc gtccaatggt tccaggatga
    23281 ttggaagggc gatgccatcc cgccgacggt cgtgcttccc tggcattatc tggaggccaa
    23341 tgccggcgag ccagttgtcc tggacgccac tggctgctat gatccgtcgg ggatcgccaa
    23401 tatcacctgg gacgtggacg gtgacggttc ggcagatctc ttcggaccga tgcacgcggt
    23461 gacgcttcgg gaaggttcgt acaacatcac gctgcgcctg gaggacgccc tgggcaacgt
    23521 ggccctggac aatgtcaccg tattggtgaa cccctcgtcg gatggaacgg tgacttggct
    23581 actctacgcc ccgctccccc tgctccttgc ggtcatcctg ttcaagaggc ggaccagaag
    23641 gctttagtta gacgaacggg attcgccgcc gttgcagata cgccatttcc agaaccggga
    23701 cctggccgac gtttggcagg tcgcttcgga atctctccgc gagcgctacg accccaccat
    23761 cttcacgcag ctggtgccct tctggccgga cggattcctg gtgatcgagg acctggggag
    23821 ggtgatcgcc ttcgtgttcg gggtcatgac cggcgttcag cacgcccggg tactgatgct
    23881 cgccgtgaac agcaattacc gcggcgccgg acttggaacc ctgctcaccc aggagttctt
    23941 ccgggaatgc gccaagaagg gcgtgcggca agtatcgttg gaggtccggg ccagcaacct
    24001 ggcggcgcaa cgattctatc tgcgcctcgg cttcttcaat gtccggcgcg tttcaaaata
    24061 ctactcggac ggggaggacg ggatactgct ccttcgctac ctctaatgga acatgctgtc
    24121 cttggtttgg ttccaaaagt agtaaggcga tttttccttc tgggcggaag agatgtccgt
    24181 gcccagcccc ttcgtgtaag aaccgtagcg gtccttgatc tgctcctcgg cgctcttgct
    24241 ccgttccacc gcacccgcga tgtgcttcgc ggtgatcagt tccgcgttct ctcccacggc
    24301 gaggtctccc gccgctcgaa tgaggccacc cagctccctc agtcggaggg taagggcgtt
    24361 gtttatgttg tcgaccttgg cggccctggc cctggcctcc ttcatgatgg cctcgatggc
    24421 cgaggcatcg gcgtgaggga tgcgcgtatc ggagacgatc tcctgggcga tgaactgcac
    24481 cagccgatcg cggttctcct cggtgtccgg catggcggtg ttcaccagga cctcgtagcc
    24541 gttcccgcag atgcgagaac gaagtggtga gaggacctgc tccaggtcct gtatgttgca
    24601 ggcgcctacg aaaatgaaac tgcaggggac gttgtccacc ttcacgctgg cgccggagct
    24661 ctgcgggtta cgacccgaaa tagggaagcg gcgttcctgc atggcggtca ggatgaacct
    24721 ctgcaggtga ccgaggtggg gcagttcgtc tatgaacagc acgccctcat gcgcctcgtg
    24781 tatcgccccg gggaccaccc gatcgtacgg ttgagttcca agctgggcat gccctccgta
    24841 cgggtcgtga cgaacgtcgc ccagaagctc ggtctccgag gaaccggtgg ccagaacgaa
    24901 agggttgcgg tccagacgga cgagcacctt gcgcggggat tgcttctccc agtcccggcg
    24961 cttctccagg gcgtcctggt ccagcagcct tatcatctcg ccgcatcgtt cgaacaccac
    25021 cacctcctcc ttcccgaaac gggtgcgggt ggtggtgacg cgctcctttc cggccgttcc
    25081 ggttaggccc gcagcgttca tctgctcgaa aaggccgctc ataaggtccc cgaaggggtt
    25141 gttggccgcg acgtccgctc ccttgttctt ctggcatttg gggcagacgc gctcctttgg
    25201 agaggaatat gcgccgcagt tgcggcaccg gtagcccagg cgctccgcca cgttgacggg
    25261 agcgttcttg ggctctatca gctcgccctc agcgaactct ttggtcttag attcggaacc
    25321 gacctcgttc tcgttcttaa cttccacgag gggccgttcc gggttctccg ggttgtgcac
    25381 caccctaatc tcttgggtgg ggcgggaaag gtgcaacgcc agggcctgcg cgatcatgga
    25441 cttgcccgtt ccgggcggtc cgaccagcag caggtgccgg cgctgcttgg cggctatgcg
    25501 ggccagggtc acggcctcct cctgaccgat cacccttaga aggggatcgg agggtatgga
    25561 gacctgggcg gtgctctcga agctccgcca gcttaccctg tccgcgccgc tcatgttcag
    25621 ttcaggtcgt ccttggacca gacgtcggtt ccggccggct gcttggtgat gttgcccatc
    25681 ttggtgccga ctatggtccc gatcttcagg tcggaggcca ggtccagtat ccgctgggtt
    25741 atgatgccgt caaagacgac cgcgaacact gggtccttct cctccttcag ggtgttgacc
    25801 agctccttca ctgccacttc cttcttgatt ccgcccatgg cgtcgagtat tcgggccttg
    25861 gaggtggagg acagctcgtt gatcatgccc ttgaacttct cctgcgcgcc ggagagctgc
    25921 ttgcgggaaa cgggcttccg ctcctcaagc tccttctcct ccacgggggg tcgttcctgg
    25981 cggtcggccc ggggctcgcg ctcctggcgc tgctcggcct tgggctcctt ctcctggcgg
    26041 ggctcctcgc gctcgcggcg atcctggcgc tcggcccggg gttcgcgctc gcggcgttcc
    26101 tgcctctcag ggcggggttc cggcctcggc tccttctcct ggcggggctc ctcgcgctcg
    26161 cgacgttccg gcttttcggc acggggttcg cgctcggtcc tgaccggctc gtcgtccttc
    26221 tccttgtcgc ggtcggccct ctcggccttc tcgaagcgct ccagcttctc gaccttgacg
    26281 ttgttgggct ccagcctctt ctccttgtcc ttggcgtctc cgaggtccag gttgaacatc
    26341 tcgatgaact ggtcgccggg gatcttgttc cggaggcact tcatgatctg cttctgggtt
    26401 agctcctcta cctcgtgggc gcgcggggct cgagcgacga agtccacctc ggccacctgg
    26461 aacatctcgc gcaggatgag ctctccaccg cggtcgccat cgacgaaggc ggtgattacg
    26521 cgttccttgc tgaggtccat gatggtcttt ggtacgttcg ttccctcgac cgctatggcg
    26581 ttcttgatgc ccgacttcag caggttcagg acgtcagagc gaccctccac cacgatgatg
    26641 gcgtcggact cggcgacgtt cggtcccgcc ggtaggcggt ccttgccgta gtaggttatc
    26701 tcttccacct ggacggactg gcgcacgctc tcggtgaggt cgatcccgga ggtcttggac
    26761 tgctttatca gctcggtgag cagttccctg gccctctcga tgatcttttc acgtttgaca
    26821 acgcgcacgt cctcgatgga ctccacggtt atcttggcct tgcacggtcc caccctgtcg
    26881 atggtctcca atgcggaagc caagataacg gtctccactt gatctaagct agatggtatc
    26941 agtatctgtc cttcggactt tccctgccgg gagtggacgt caacttcgat cctgccgatc
    27001 ctgccgctct tctgcaggtc tctcaggtcg agctcgtcgc ccaacaatcc ctcggtctgc
    27061 ccgaatattg cgcccaccac gtccggtttt tcaacaatgc catcagcgtt aagcttggcc
    27121 ttgaccagat acttggtggt gcttgggtca atgttcatat tatcacctct gtcaagctga
    27181 aaaaggagaa cggctctcgc acaccaaggt ccactatgcc catcaagacg tctgtcctga
    27241 cgaacctgaa cgggttttcc atccgttacc cggcctaagc tggccgcgtg atgaaagggt
    27301 gatagtgatc atgtgatata ggaaagcccg gctcgatttc caggcttcga ttgacaatac
    27361 cataaaaatt caagatattt atatacttta cgtagcggca aacacggcgt cagaaatctg
    27421 gcgtttccga ccttatccgc ccgaggcgac cttgattatc cgcagttggt ctccatctag
    27481 tagaggggag tcgaccggca ccggcgtcct tccccggacc acgatgtggg cgtccggata
    27541 gaggccaagc gaatcgagca tcgcctgcac cgtggaacct tccggaagac ggatctcctt
    27601 cgcctttcgg tcgacctcca ccgtcagcac gacatcgctc atcggcacgc tcaagcgcta
    27661 cgggaaataa atccttttgt ccaattctta cgtttcgttc caaatcgtca aatttgaaat
    27721 atgagcaggg aaatgcccat gcaagccaag gtagcctagt ccggaaaggc ggtagcctcg
    27781 aatcggccac aggccgatgg gatagctact gacttcacgt ctcgggagtt caaatctcct
    27841 ccttggcgcc acttctcaca ctatgccctt gaagaacccc gggccgagca gtctttcctg
    27901 gatgtcgttg gcgaaggcct ccgccacctg gtagtagtcc ttgccgaact ccttctccat
    27961 gaaccgctcg tattgaaggt ggactttggc gtccgtctcc agctgcagac agttctcgat
    28021 atgcgggaac accaagttct cttcctcact gatgtgcaag gtcatgtgct ccacgagctt
    28081 tcgggcctcc ttctccgcct tcggcagatc gccctcatcc agcgccttga gcgcgttcct
    28141 catcatccga cgggcttggg catgctcctt cttcaaccgc gaaagcgttt ccgccacctt
    28201 cgggcattcc acggccgcgg ccttgaacag gaatcgctcc tccttggcgt gatggaaacg
    28261 gtccaggaat tgctccagga aggccaaggc ctcccggaac tcgacgggat gccggtctgc
    28321 ccggtgcgac ctcataagtt cgcctaccac gtccaggacc tgtcggacga tgccatggtc
    28381 gtattgaagg agggtcaccg agatcctcat gataggaact aggtacgccc acctttttat
    28441 tgatttggct ctcagcgggc gccgtaccct tccaggtcta gggcgacctt tcggtagcca
    28501 agcttcttca gggcctgtac caccttctcc cgctcctgaa acaatcgggg aacatcctct
    28561 ggggcgacct ctattctagc ccagtactcg tgatcgcgca cccgcaggtt cttgaacttg
    28621 aacggtgcca gagcggcttc cgctcgctcc acccggcgca atatcgtcga ggtgatccga
    28681 acatcgtgcg ggaccctcgt cgccaggcac gtgttgcttg gaaggtccca gttcggaagg
    28741 cccaggtcct tcagtagagc gcgcacttcc gccttcgtga gctgcgcatc gatcaacggc
    28801 gaacgcacgt tgaggtccat cagcgccgcc cgtcctggac gcacctcctt cagatcgtcg
    28861 agatggctcc cttcaagtat gtgggatatc tccagctccc gggcctcctt cttgatccgg
    28921 ctgaaaatgg cgctcttgca gacgtagcag cggtcctccc agttgcgcgc gaactgcccg
    28981 tcgttaacca ggtcgatctt taaagttaca acgtccacgc ccagcttctc ggccagatgt
    29041 atcgctccgc tctgctcctg cggaaagaag atctcgccta tggccatgaa ggccgtcact
    29101 tccgccccgg aatccagggc ggccttgagc aagagcgtgc tgtcagcacc gccagagaag
    29161 gcgacggcca ccctttccat ggatcgaatc gatccgacca acccctgata cttctttttg
    29221 gccgcttcca tctccatcgc aggtgcaatg gcgaaggcga tatttattat gggtccggtc
    29281 gattgtgttc atatgcccag aaatcattgt cggcgcggtt gcggggggcc agggcgcccc
    29341 atgaaaccac gagttctgcg gggcccttcc aactacagca gtttcagacc ttcctccgaa
    29401 accacttcgg aacccatagt gatctatccc gatgaggtgg aggcccttcg tctggtagac
    29461 caccttgggc tcaaccaaga ggaggcggca aagagcatgg gggtgtcccg cggcacggtg
    29521 tggaggtgcg tggacagcgg caggaagaag ttgatatcca tgatcatcga ggggcgaccc
    29581 ctccaagtag cgaacgtcga cgaatcgtgt gacaattgtt aggttttcct aaattactta
    29641 tattattgtg cttatgcaca ttattgacgc cgttaaaatc ggccgaaagg agatgaaaag
    29701 atgccatatc gagatggggc tggtccccaa ggaacggggc cgaacggtcg agggatggga
    29761 ccttgccggt ccggaggcag ggtcgccttc gggatgggaa gggataggag aatgggccac
    29821 ggtcgcgggt tccggttcat gtcggaatgc tccgaagcgg acctcaatac gaacctagag
    29881 gcgaaggtag aggccttgga ggccaggctg aaatatctca aggcgcaact ggctggcgag
    29941 gggaagggtt ccccatgaag gtggccgtca cctcgagcgg tccaggaacc gaggacctga
    30001 tggacgacag gttgggcaga tgcccttact tcgtcatcat ggacacctcc tctggatcga
    30061 tagagtcctt tgccaatccg gccattgacg cctctagcgg ggcgggcacg aaggccatgc
    30121 aggcgctgat cgacaaggga gtggaagtgg tgatcaccgg tcgcatcggt ccgcatgccc
    30181 aggcgatgct ggaagagacc gatctcaaag gggtcaccgg gcgatccgga attgtcggtc
    30241 aggtcctcaa ggattacctg gccgattcca aatcctgaaa ccacttatca acttttcaat
    30301 ccagcttcag ggcgataccg cttccccggc gatccttgga cctggaacgc acttctttcc
    30361 aaatccgttg atattccaaa gcggctggtg aatcggggaa cattgacggc aacggctgca
    30421 tggccttgac cgattccaac acgttggggt cgtagggtat gcgtcccact atcaccaccc
    30481 cctgccggcg gcagctttcc tctatctcac aggtcatccc ggggtgcagg tcccacttgt
    30541 taacggcgac gcagatgggt atggaaaaat gatgtgccag ttcgatcaag cgcatcaggt
    30601 cgtgctcgcc agaccggcta ggttcggtga tggccaatat gaggtcgacc ccgctgacgc
    30661 tcgctatcgc cggacatccg gtgcccggtg gtccgtcaat gagcaccgtg tcgatcccat
    30721 ccgatccagc taggtcatcg gccagtcggc gtacgatcgt aaccagcttt ccgctgttcg
    30781 actctcccgg gaacaggtcg gcgtagacca taggtccgcg ggcggtgtcc aggacgaata
    30841 tctctccgga cttacgcagt gacatactga ccgccccagc cgggcatact acctggcaag
    30901 ctccacagcc ctcgcaatgg atggcgttca ccttgaggtc gtttatcgcc tcgaaatggc
    30961 agttgtcctc gcatcttcca cactcggtgc agaggtccag gtcgatcgct gcggtgtagg
    31021 cgccgaggta atcgtccttg gtccgcggtc gaccatgcat cgtcagggcg agattggccg
    31081 cgtccacatc gcagtccgcc agtaccagat cttccgagta ccaggacatg gaggccacgg
    31141 cggtggtctt tccggtaccc cctttcccgc tcagaacggc gatcttgatc atcttttcaa
    31201 ccccacgatc tcaatgaaca catcgttcag tttgtctgtg agcttgggca tggcctctaa
    31261 aagggtccct cctctggcat agatctcggc gacctttctg tcaaagggga ccttcagcag
    31321 aacaggtacc atttcagtct tgcatagcga ctcgacctcg cggtcctcgc caaatgaacg
    31381 gttaataatc actccgcagg gaacatccag gcggcggcag acctcgatca tccccttcag
    31441 gtcgtgaatg ccgaagggcg taggttccgt taccagcagt gcgaagtcgg aaccctctac
    31501 cgcctccacg gcagggcagc tggttccggg cgggcaatca atgatgaccg tatcgtccat
    31561 ctccttcttg agcctcttga tgatggggac ggacagggcc tcaccggtcc tcagctcccc
    31621 gcagaagaaa cgcatcaatc ctgcggttcc tatgtggaca gtgcccaccg gccttccgga
    31681 catgatcacg gcgtcctgag ggcataccag gcggcacacc ccgcaaccgt ggcagaggct
    31741 ctccatgacc ttgaccttct tgcccaaacg gaccatggcc ccgaaatggc atttcgatac
    31801 gcatatcccg catgcatcgc acttcgaccg gtctatggtc ggataaggga tcacgacctc
    31861 ttcctcggac ctcagatagg ggtgaagaaa gatgtgggca ttggcgccct caacatcgca
    31921 atcgagaaag gtcagcggtc gatctagcgc taaacccaga gcgcaggcga ctgacgtctt
    31981 tcctgtgccc cccttaccgc tggccaccgc cacgatcatg ttcgaacctc agtgatcgtg
    32041 ttccttgcaa gcgttgtcgt ggtcggcccg gatcatcttt ccggcgttgt acgcctcaag
    32101 cgtttccccg accgtgccct tggcccccac gaagacctgg atgcccaggg atgacagcat
    32161 gtccaccgcc ttcggcccca gacccgaaca gagcatcact tggacacctg ccttggccag
    32221 cagttcgggt ggcattccca ctccaccccg atgctcgctg gtgttctcca gaaagctcag
    32281 cgttccgctc tcggtgtcca tgacggcgta gtccggaacc tttccaaaat gctgcccgac
    32341 ggtcgacgac aatcccgatc ggtccatgac tggtattgaa accttcattg aacgttcact
    32401 atccttaacg ccgttcaatc ggtactccgg cataaagata atccctgatt caaccccatc
    32461 gttcgaacta attcactatc acttcgggac catccaagaa cgatcggatg ccccggtgaa
    32521 ccggtcccag gtcctaatct tctttcaggc ggccgaccag gaacacggcg gagccgatga
    32581 gtatgaaccc tacgccgaac gcctggagac tggaaatgat atacatccat aggaggtcca
    32641 cagcgcctcc catgatggtc aagagcagtc cgatcgcaaa aagcaaaagt cccgcccaga
    32701 cgatcttgtt cccggctttg atgaactcct ccctcccctt ccacaccatg atgttatcac
    32761 tgttcgacca ctccttaaaa ttaattctca tgatatcaat taaaaaaatg ttcgacgatc
    32821 tccatgagtg ggcaaccgat aacgataaaa taggaaacat ctcctcccag gtccgatgaa
    32881 cgtccgcgac gtcttggatg cctaccgaaa gggcgatatc gacctgcaga gggccgagca
    32941 gctgctccgg atggatttcc tcgaacgcgt cggagagcac acgcttttcg atcacgcccg
    33001 cgaggccaga cgaggcatac cggaggtcat ctggggggag aacaagtccc cggacatggt
    33061 ggcggagatc gtttccaccg tgctcaagga ccgcgacgcg gttcttatct cacgagcctc
    33121 accggagcac gtcaaggcac tgaaggccac cgtgaatgag gaacatgtgc ggtacataga
    33181 gcgttccaag ctcatcgtcg ttgaccgccg caaggaccgg ccaaagatcg gaaagatcgg
    33241 gatactgacg gccggttcct ccgacatagc cgtggccgag gaggccaagg ccatggccga
    33301 ggtcatgggc tgcgaggtgc tcaccgaata cgacatcggc gtggcggcat tgcaccgttt
    33361 cctcgatccc ttggctaaga tgctggacca gggcgttgac gccttggtcg tggtcgccgg
    33421 gatggaaggc gcgcttccca cggtggtctc cggcctggcg gacgttccga taatcggcgt
    33481 tccaacgtcc gtaggttacg gctacggcgg aaagggcgag gcggccctca tgggcatgct
    33541 gcagacctgt tcgcccgggc tcgtggtggt gaacattgac aacggaatcg ccgccggggc
    33601 caccgccgcc ttgatcagtt tgcgctgccg gcggaacagg tgagatgatg aacatacgcc
    33661 agctccgagc gggggacgta ccgtccgccc aggcgctgat ggccgacacc tggtccaacc
    33721 ttctcaagcg gcagaccggc ctggacatct cctatccggt aagacaggct acctggtata
    33781 cttcccggtt acggcacgag cctttgggat gcatctgtat cgaggagaac ggaaagctga
    33841 tagccaccgg tttcgccctg agctgcggca acgtcggttg gatagggccg atggaggtgc
    33901 gtccggataa gcagggaaag ggatacggct ctcagctcct gttgtcgctg gagacctacc
    33961 tttccacgcg cggctgcaag gcggtcggcc tggagaccat gaaggacgtc tcccgtaatc
    34021 tggacttcta ttcccaggcc gggtatgccg tggagcagga catgttgttc ctggagaagg
    34081 actggctgga cggtcaggac gccgggcgtc cggaagggtc gaagttcgat cccaaggaga
    34141 taaaaagact aggctcgacc ataaaccccg gattcgatcc gtcggtcgag ttccaggtgt
    34201 acgaggagat gggcatcggt cggacgctca ccgcggaggg ggcggtcgct cttctgctca
    34261 cggatcccat tcccggctct ggaaaagcat atctgcgaac ggtgctgacc gagggatacc
    34321 accgtctgga cgaggcgata ggcctggtgc agaaggcgga acgggaggct ctgtggtccg
    34381 gagcgagatc gatgttcacc atcatcccgg cgcagagcga gctactgacc tccctcatca
    34441 ggggcggtta caagcccaag ggggcggacg tgcgcatgat gaagggaaag ttcgtgcgca
    34501 gtcatgaatg ttccatcttc tcctggtccg gttaatggtt ctccggcatt attatggcca
    34561 ttactatgta ggccagtatc agtactcccg aggttagcaa cgtgcccacg acccatagta
    34621 ccctcaccag gaaggggtcg gtctccagat actcggccat gccgccgcat acccctaaga
    34681 tgatcttatc ccggctcgaa cgtcccatgc gtttccctgg agcgtaggac gcctgcggag
    34741 ctgctggcgc cggaggcact ggcggaacgt tcacgttccg cgggggaaaa ccgaccttgc
    34801 ttgctttcat tatcacgccg atataaccga gcaggatgat cagcaggaat atgatgtaga
    34861 ggacggaaga caccatgtct cccatggccg tcaggaagtc atccgatcgc gactcgccga
    34921 ggaatccgaa ggccttggac accacccaca ggacgaaagt gacgatgatg gccgtgatca
    34981 aaggcgatat gatggacgat tctctgggat acttcctggt gtagtagcca aagtagaatg
    35041 ccagcaggaa catcaggaag aacagcagga gcgtgtcccc caggaattca gagaacctct
    35101 cggcgaacaa tgattcgctc gagagcgcct tgaatatctc catcaacagc agaacgaata
    35161 tcaggcccag gaaggccttc agcagcgggc cgccaccccg gaaggtccga tcgaacggcg
    35221 tctggttcca caccgccgga gctctcttca ccggttggct ggcagttggc tgttgggtca
    35281 cgatcttacc tccgcatttt tgacagaagg aggcctggtc ctcgttgacc gctccgcact
    35341 tagggcaata caccattcga catcccgacg atgagaacag gtcacgacct cataatcgtt
    35401 gcccttgcga cgatagctca ataatcctcg accgccatca tcgggacatg gccgagggcg
    35461 aggaagcgag ggtgcgcaga gttctggaaa gggcgaagga ggagtacggc ttcgttccgt
    35521 tggtttcgga ggtgatgtcc gatcgacctg accttttctt gccttatgcg gagatatcga
    35581 gcggcctgtt cttcaaaccc aagcacatgg accgcaagac ggcggagctg gcggcaataa
    35641 ccgccggagc cgcgctgggt agcgagaact gcctgggagt tcatatcctg caggccttca
    35701 agatcggcgt cagcgaggag gcggtcctgg aagcgatgat actgggtggg ttcatgagca
    35761 tgaaccgcag caattccatt tccttccgat gcctcaaggc ggccaaggag agtatgagat
    35821 gaggtgctcc gtcggtagcg tgggaagggt gctggtcatc cgcctggaag atggggacat
    35881 actgcacgag tgcgtggaga gggcggccaa ggagaacgat atcatcagag gggcggtcct
    35941 ggccctcggc ggggcggacc ggggaagtcg aatggtggtc ggtcccaagg acggccgcgc
    36001 ggataggatc gagccgatga tggcgcagct ggccggcgag tccgagctcg ccgccgtcgg
    36061 tacactgttc ccggacgaga acggggtacc gtccctacac atgcacgcct cggccggaag
    36121 ggatggccgg agcgtcaccg gctgcgttcg tgccggcgtg aaggtatggc tgatacagga
    36181 ggtggtggtc atcgagatac ttggcagcga ttcccggagg gcgaaggacc ctcgcaccgg
    36241 cttccatctg ctggagcctt gatcagaagg cgtttacgca acggatgcct ttttctgaga
    36301 acctgcgacg aacggtggcc tccaggctgc gatagtcctc ggcgcggtgg gccttctcca
    36361 atcgttccgc cacctccgtg ccgttagctc tccgggcgat gtcgtcgaac atgcctggcc
    36421 ggggtctgaa gcggtccagc atgacccatt tgatgccggt agatgacagg gcgtccacca
    36481 tctcgtcaat gtccacgttc gtcagtaaag gaagcagcgg tcctatcagg gcgtaggcgt
    36541 tcaaaccctc ctcggacaac ctacgcaggg catcgactcg tcttcccggc aagggggcgc
    36601 caggttccag catcgcgctc agctcgtcgt tcaccgatgt aacggttata ccaacctctc
    36661 ccttcagctc cttgtagaga tcgatgtctc gcagtatgag gtccgatttg gtgaggacgc
    36721 tcaccgaaag accgtgcgga actatttcca tcaggcaccg tctggtgatc agcagatgcc
    36781 tctccgcctc ctgataaggg tcggtcacgg tgccgaggcc gatcattcct ttcttgccct
    36841 tgatctcctt ggccagagct tgcgggaggt cggtcctggc cagtatcgtc gtccattccc
    36901 ctcggggcct tttggtgacg tacggcgcgt agcaatacag acaatcgtgc tggcatccca
    36961 cataggggtt cagcgcgtag tccagtcccg ggaggcggga agccgggaga gccaccctgg
    37021 tgcgaacctc acttatgcgc ggcgccttgg gcaccggccg gccgtcgtcc atcatcatga
    37081 acaggtcaag gttcgacata gtcatcgatc ctccgctgta tcttgaggtc cttcaatatg
    37141 gcgctgtggt ccgtccaggt gctgatcggg atgtccatgc gggtctggac gtatgctaag
    37201 gcctggtcca aggtgttgaa cttgcgtggt ctctgtgtga gcgccattcg cacgttctcc
    37261 cgtacgttcc agacgcccac cggaagcaga tatcctgggt gtgcctcacg gaatatgacc
    37321 gctccggact gccggcgttc cctctgcagc agttcgttca cggccaaccg cgcagcgtag
    37381 tagcagcccc cgatctccgc gtaatccttg cgaccgtcga agaactcatg cgaggatatt
    37441 atctccacct gcagcccggc cgggttccag acggtgttgg gataccaggc ctcgatcagc
    37501 tcgtacctcc acgacgtagg cgtgagcatg acgctccaac ggttatcgag ctggtcccaa
    37561 tcgtagaccc ggaactcatt gatcagcggg aaggtcttcg tgcttttcag aagatccttg
    37621 cccagcatgt catccacggc ggttatgctc cagcgggtcg ggaccagccg gcggttctgc
    37681 tctattccga aagcaccaat gctgaaggcc ttctggatgc gggagatcag aacctcattc
    37741 ttgtaaagtc ccttgaccgc ctccaccgcc ttgaggtccg tatcataata ggccttctcc
    37801 acccggtggt cgtacttggg attggttatg ctaagtttct ccagcttggc cgaaggcccg
    37861 aagggttgga tgttgtcatc gagaactatg cggccggaag gcttcttgga gaaccgggcc
    37921 tccacatcca cggagttcac cgcgagtgcc agttcccgag tgaagtccac gatgcgaccg
    37981 gcgttctgaa agttcttgac atccaccaag tgctttcctc tgaccaatcg gaaccggaag
    38041 tccacgatct cctccatgga cttgcccatc cactgttccg gggtgtccat gatcaacgtg
    38101 tcgccaaggt caggaggtac caaaggaccg atgtccacct tggggtagcc gtatcgtccg
    38161 acgaacaccc ccggcggcga actgccgtga aggtcctgag cgtttatcag ccgcttagtc
    38221 ttcgtatacg aatagaactt gatcatcagg gggcagcggt ccttgccgca gaggttcttg
    38281 gaccccttgc agatatggca caggctggag ctgtccttgt gggcggaggt gaacgtctga
    38341 tcatccaacg gcaacggggc gaaaccttgc attatcgtcc tttcaaccat gctcagccta
    38401 tttgaccgtt ttccagggac ttttaaaagt gaggctgcga gaagattacc ttgagcaact
    38461 tcaacaacgc gctcatatcg gccttggtgc cgttctctat tcccgggagg tctgccgtct
    38521 cgtaatcatc gccatcgaag cgcaaggcca tgatggtcca cctttccggg cctcctaggc
    38581 gcggggcgga gatcagcgaa gctccgtacc cgttcggaaa gcggtacacc cgctgctccc
    38641 tcccgccctg cattccaaga caggacctgc aatagcccac gtcaacacgg aaccgttcta
    38701 ggtcctcgtc catggaccag tgaggagttc agctagacaa ataggttcgt agagcggtcg
    38761 gcagctacta ttttatatcg tgttgacatt ctccaaggtg tcagcatatt gtttttaggg
    38821 atgctgaaca cgacaagctt atatagaagc gataaaatac cgaccgtaag gaggctcatt
    38881 atggcttacg gaatgggaca aggtaatcag cctatcatag ttcttcgcga aggtactgat
    38941 agatcaagga ataaggaagc acagttcaac aacatcgccg ccgcccgtgc ggtcgctgac
    39001 tcggtcaagt cgaccctggg cccgaaggga atggacaaga tgttggtcga ttccatgggc
    39061 gatgtcgtca taaccaacga tggtgtgacg atcttgaagg agatcgacgt ccagcacccg
    39121 gctgccaaga tggtcgtgga gatagccaag acccaggaca ccgagtgcgg ggatggtact
    39181 acctcctccg tcatcatcgc tggcgagctg ctgaagaagg ccgaggcatt ggtcgagcag
    39241 aacatacacc cgaccatcat cgccaacggc tacaagatgg ccgccgctga ggcgatcaag
    39301 atactggaaa ccatcgccgt gtccgtcaca ccagacgaca ctgagatgct gaagagggtg
    39361 tccatgaccg ccatgaccgg caagagcgtc ggcggccagg gcgagttcct gtccgaagtg
    39421 gccgtgaagg ccatcaaggc cgtcgcggag aagtctggaa agggctacaa cgtcgacgtt
    39481 gggaacataa agatcgagaa gaggaccggc ggctccatag ccgagaccga gatcatcgag
    39541 ggcgtcgtga tcgacaagga gcgcgtccac ccccgcatgc caactcaggt caagaaggct
    39601 aagatcgctc tgctcagcgt tccgatggag gtcaagaaga ccgaggtcga cgctaagatc
    39661 cagatccgcg acccctcgca gatgcaaatg ttcctcgacg aggaagaggc cgtactgaag
    39721 aagatggtcg accaggttgc cgcctccggc gccaacgtgg tgttctgcca gaagggcatc
    39781 gacgacctgg tgcagcactt cctggccaag gccggcatat tcgcctcccg caggctcaag
    39841 gagtcggaca tggagaagat cgccaaggcc accggcggta tcatcgtcgg aaagatcgac
    39901 aacctcggca agagcgacct cggcctggcc gatgtcgtcg agcagaagaa ggtcggcgag
    39961 aacgacatgg tgttcatcac cggatgcaag aaccccaagg ccatcagcgt gatcgtgcgc
    40021 ggcggtaccg agcacgtggt cgatgaggtc gagaggtccc tgcacgacgc tctgcgcgtt
    40081 gtcggagtgg ctctcgaaga tggtaagatc gttcccggcg cgggagcccc cgaagtggag
    40141 ctctccctga gattggccaa ctacgcctcc accgtcggtg gacgcgagca gctggccatc
    40201 gaggccttcg cctccgccat ggaggtcatt ccctgggcac tggctgagaa cgctggactg
    40261 gacgctatcg acatggtcat ccaactgaag tccgctcacg agaagaaggg agccaactcc
    40321 aagtacatgg ggctggacct taacctcgga aagccggtcg acatgctgaa ggccaatgtc
    40381 atcgaacctc tccgggtcaa gacccaggcc gtgaagtccg cggccgaggt cgccaacatg
    40441 atcctgagga tcgacgatgt catcgcctcc aagaagtccc ctccggcacc ccccggaatg
    40501 gacggcatgg gcggtatggg tggcatgggc ggaatgggcg gcatgcccgg gatgatgtaa
    40561 gcatccagat agctcaaacc acttcctaaa tctctttcta ttttatcatt ttaatcatcc
    40621 ataataccat atttttaata gagtgccaat caattcaata attaactaaa cgggtaggat
    40681 ttgacatgaa aaaaattata gggacactat tgtgcgcact taccttcctg gcgttactgg
    40741 tctctttggc tgttccggca ttggcaacac ctgccgaggc tccggaatgg aaccaaggcg
    40801 accgatgggc atatgggatg gaagttgatg ctgatgagga gctccaagag gaattggaga
    40861 acgtcaccac gacggtcgac cagttcctgg atgacatcga aggcctcaat gccaacctga
    40921 acgatctgaa cgttgcagcc agctcggagc tctgggtcct cttcgaggtg accgaagcta
    40981 acgatgatgt gtacgttctc agcatggaca tggccgcgat gataagcgta gatgcgagca
    41041 tatcggtaac cgcggaactg ccagccgagg gtacttatga tatcggggag cttatgaccg
    41101 ccgagagaga ccccgtgaca atgtccgcga gcgtcgacct cactatgttc ttgaccgtca
    41161 gtgtggacgt gacctttgac agcgatacga tggcccttaa gtccatcgag gccactttga
    41221 agctcaccgg agcccttgac ctcaccgctg ataacctgcc cctatggtta cctggactga
    41281 tggacaacga tctcaacgag tcattgaccg gagagatcaa ggtcgaatac acggattacg
    41341 atatcaacgc tgatctggaa ttcaacctgg ccatgaactt ggagttcgtt cccgccttga
    41401 acctgtggga cttcccattg gatgtgggag atgattggaa cgtcagctcc aatgccaccc
    41461 tgagcggaag catgagcggt tcactggacg tatcaggtct gccatctgat atggaggatg
    41521 ccttcttcga aaaggtggcc gataagatag gcgcgaacag cttcccgatc gtcttcgaag
    41581 acctcgacct cggtgactgt ccgttcgatg gcggtgtcat ggaggagacc accgagcaca
    41641 taggcccggt gaacctgagg tgcaccgacg tgtccactgt aaacgaccca tactggaacg
    41701 acataaccgt ctacgagatc aacgtggtcg acactcctct gaacatgtac tattccccgg
    41761 acgtagggtt catgtcctac ttctcgatga acatgggcga gatgggcgag gagatgccag
    41821 atcgagattt caggatggat gcggttgatc ccgatgacgc agaggccaac atcgcggatg
    41881 tgaccgaacg ccagggtgaa gtgcaagaag atagcggagc gcttggcttc ttcactgacg
    41941 cgccctacct gggcataatc ctggtggtcg tgatcgtggt ggtcgtcgtg gccgcgatct
    42001 tcctcatcag gaagaagtag gtctgaagat cttttccaaa cctttttcat tttcttttta
    42061 tttcttctgt tctaagcaag ttatataccc ttttagacgc taatggccaa taggataact
    42121 gggggacctc gaatgaaagt catacttgta tatgattccg tctcgaccga aaaattgacc
    42181 gccaaggtcg ctgaagtcat cgctacgact ctgaaaggca agggattgga cgtcactacc
    42241 gttccagttg gcgatgccaa gcatctgaaa ctcgaggagt acgacgctct ggtggtcggc
    42301 acgcctacca tggcctgggc gcccaccaaa ccgatcaaag agttcctgaa agggctggat
    42361 gtgaacaagg tcaagggtaa gaaagcagcc agcttcgaca cccagatgag atcattcatc
    42421 agcggtaacg ccaacaaggc catggaatct aggttcaaag agctgggcat gaccgtcgcc
    42481 tgcccccatc tactggcata cgtgaagagc gagaagaagg tctatcactt cctggacggg
    42541 gagctgcaga aggctgaaga ttgggccaaa ggccttgccg atgcccttag caagtaacgg
    42601 tcggtcgttg cacaaccatt aatcacttaa tgagaatggg agtcccatgg tcgtccgctc
    42661 catcaatcct cgcaatggac aggtagttaa ggagttcgtc tccaaccttc cagatgatgt
    42721 tctgccaagg ttggtgaaag ggcgcgatgc ccagcggaaa tggatcggcg aatgggacct
    42781 ggaggaacgg atagaagcgg tgctggagct tcgctccgcc cttctcgcga tgaaggacga
    42841 catgatcgct acggaaatgc tggaaggggg atttcctcag agggatgtca tcggcaccta
    42901 taacggggtc ataaaaggtt tcgaacacta tgccgccgag gccaaggcca ccggtgatta
    42961 tgagttcccg ctcgatccag caggctggcc tgataccaag gccacgatca acctggtgcc
    43021 tcatggcgtt atcgcgcaca taggcatctg gaactacccg ttatggcaga ccatgataac
    43081 tctgatcccg gcgctcatgg ccggcaacgc tgtggtcttc aaaccgtccg agctcactac
    43141 catgaccgga atgaagatcc aggaggcttt caacaagacc agcatgccct ctggtttgtt
    43201 tcagaccctg atcggtggtc ccgagatcgg taaggcgatg gtcgctgccc cgttcgacgc
    43261 cctcgtcttc accggcggca gagctaccgg gctggacatc accaggaatg ctggcatcaa
    43321 gccaatgata ttggagctat caggaaacga tcctgggatc gtatgctcgg acgtcaacgt
    43381 tcacgagacg gccaggggaa tcgccagcgg tgccttctcg cacggggggc aggtctgcat
    43441 ccgcatcaag cggttgtatg tggaggaagg cgtggccgat gcctttatcg ctgagcttaa
    43501 aaaggtcgtg gccaggatcg atgttgagga acaggtcggc ccgctcattc gtgaggaagc
    43561 gcgagcgcag gttagggaaa aggtccagag ggccgttcaa gccggttgtg aactgttgac
    43621 tggtggaaaa gatctccctg gcccgggtta ttatttcgaa cctacggtcc tgaaggtcac
    43681 cgacgacagt ctggagatca tcaaggagga gaccttcgga ccagttcttc ccattcgggt
    43741 ggtaaaggac gtggaggagg ccatcaggct cgccaaccag agcgattacg gtcttggtgc
    43801 caccgtctgg acctgcgatc ctgtcaaggg cgaggctatc gccaggcgtc tggaggccgg
    43861 gaacgtctgg ataaacgaac atggccggac catcaattgc ggagagctgt tccagggatg
    43921 gaagtgcagc gggatcgcca gcaccaatcg tcgtatcacc ctcttcatga agaagcggac
    43981 catcgtcaat caccaatctt gtgtggcccg gccgcactgg ttcaagtgag ctaagaaaat
    44041 attttttatg ccgattctca tccagtgtca tggtggggaa cagcggggaa atggtctcgg
    44101 taaggggctt atacaagcgg tataaggacc tgccagttct tctgaacttg agcttcgata
    44161 ttcccaaagg ctcgatattc ggctacatcg ggccgaacgg ctccgggaag accaccacca
    44221 tcaagatcat gaccggcctc atccgtgatt ttcagggcga tgtgaccatc gaggggcgct
    44281 ccatacgtaa ctggaacacc gagctcagtt caacaatcgg gtacctgcca cagcagacct
    44341 cgctccagga gtggaggacc gtggaccagt ctctgcatac cttcgggcga ctgtctggcc
    44401 ttcaggaatc tgaggtatcg aaacggataa aggaagtgac cgaggaactg ggcataaccg
    44461 aatatcgaaa gagaaaggtt aacaagctgt ccggcggaac gctacagaaa gtgggaatgg
    44521 cccaggctat gcttcaccgg ccaaagctaa tggtgctcga tgaaccagtg gccggactgg
    44581 accccgagag ccgggtgctc ttcaagaacc tctttcgcca gttatctcgg gagggaacga
    44641 ccatattctt ctcctctcac atattgagcg acatcgagga cgtcgcggac accatcggga
    44701 tactgggtca gggtcgtatg cgttatatcg gttccatgga ggagcttagg gaaagggttg
    44761 gtagaagcac cgaggtgcgg ctggagacgg tcgagccgct gcttaacgat tccgtgctcg
    44821 agattatccc tggcataacc agggtggaaa gggtggccga caaccggttc catatattat
    44881 taagggaaca cggagagatg gacgccgtgg tggaccgtct gatcaaggcg gtgctcgccg
    44941 agggattgca tatcagggcc attcatccca accggcaatc gctagagtcg ctatatctca
    45001 gctacaccga ccaggagggg agcccatgag cctatggttg ctcttcaagg acgaactgaa
    45061 cggcttctac cgttccaagg tcatgctggc cctgtgggtc ggtcttccgg tcatggcctt
    45121 gctgctgtac ttcctggtgg atgacatcga gggaataccg ttgaccgtgt tcaccgggct
    45181 cctggtctcc agtatcggcg gccttttgac gtcggtactc atagtcgtca atatcctgaa
    45241 cgagaaggag aagaaggtct acgacctttt cttgatccgg ccgatacgaa gagagaacct
    45301 gctgctggcc aagttcgggg cggtgttcct atgcgtcatg gtggcatcat tcatagccat
    45361 caccttggcg gccatactgg atagtgccaa cgaaggttac gatatcggga gcatcctgac
    45421 ctcgatgaag gactccttga taatcaccgt atccttgatg gccatcaact gctcggccgg
    45481 agtcctcatc ggcgtgttct ccccgagcgt tctggtaggg gtgcttctgg tcctgttcgg
    45541 ctccaatcag ctctcttcgc tggtgctcat cccgatgatc tctgggtggg gtgagatgtg
    45601 gatggtcggg ctggcctcca taggaatatc tgcgcttctg ctgttcggag cctctctggt
    45661 gtttcgaagg aaggagttct gatctcagag gacctcggcc gacatgtgag cgtcgatcag
    45721 cacatcgaaa tttagcgcgg tatcccagcc tgcctttcga aagacgtcca tgaaccccat
    45781 cgctatcaac agtcggtggt taggtatctg ggagatgagg agcttcacgt cctccaccgg
    45841 gcatccgaac ttcggtatgg ccaatccgcc cagtatgacc accacatccg cttcggtcga
    45901 tcggaagggc tctgtgccta tctgaaaacc cgccccgtcc acccatcgca tcgttcggct
    45961 acggtcgatc tccgctctgg ggcagaaacc gaaatgcatg tttcggtctc gcacggcata
    46021 tgccagcaat tgagcgaaag gtgggcagac cgcctcagaa ccaacgaaca gcaccttgct
    46081 accatcgtcc ttgccgacca gcgcctcgcg gaacaatctg gtcagtccgg aaatgccgtc
    46141 tgctttgacc atgttgcctt ccagttcgat tctcaatgat atttctttct atggcatata
    46201 taaattgtat tgtatacata ataattaact tcgggatagg atcttttact catgttttgt
    46261 ccagctcatt agaatatatt tacataaata atatattata ttataatatt caagtagtat
    46321 tgataaatta aatgttatat ctaaactaca tataataaat tagcaaaatt aaacatttac
    46381 ttcgttggct caagacgttg ataagattaa catataatat ttgctattag tactaaacaa
    46441 attaaaataa tatagcatat acattaaact gtatccaaac gtcagacaat cgtcggctat
    46501 tatatatgct ataatacaat tatgacctga ttcagcggtc aatatgtcag acaatgtgca
    46561 gctgagagca gcgatatatg ccagggtttc caccgaggat caagcccggg aaggttacag
    46621 catagctgcc cagctcaaac gtctgcgatc ttactgtctg gccagggggt ggaccgtcgc
    46681 caacgagtat gtggacgacg gtttcagcgg tcggagcccg gaacggccag agtacaagag
    46741 gatgatgcac gacaaggaca tctgggatgt ggtcgtggtc ctcaagatgg accgtatcca
    46801 tcgtaacagc cggaacttca ccatgatgat ggacttcctg cgttcctgga acaaggagtt
    46861 caactccacc caggagaact tcgataccac tacggccatc ggtcgtttcg ttatggacac
    46921 cgttcagagg atcgcccagc tggagagcga gcagatcggc gaacgggtaa aggtggccat
    46981 ggtccagaag gccttggaga aaaaaggtca tctggggtgc ccggaacctt acggttatag
    47041 gtatctggaa ggccagttgc ttatcgatga tagcgaggcg caggtagtag agggcatctt
    47101 cagaatggcc tcgaacctct gctcgttagg ccagatagtt gaatggttga actcatctca
    47161 catcccgacc aagaacggag gggaatggca aagatccacc gtccacggga tactggccaa
    47221 caggatgtat ctaggcgaga tggtctggga cggcctcgtc caggaagcac ccaatctgaa
    47281 gatcatcgat tcccagctat ttcaggaggt ccagggtttg ctcgcccaga ggatgaagtc
    47341 caggcgcacc cctaagcgca taccggccaa gtcactgttc cggagcgaag cgcatgccta
    47401 gggcggccat ttataccagg gtttcaaccg aggaccaggc caaggaaggt tattccctgt
    47461 cggcccagaa acagcgactg gaggcctatt gcgacgctca gggttgggac gtggcggatt
    47521 attacatcga tgacggtcat tctggacgta acacgcggag gccagcatat cagaggatga
    47581 tggaagagcg tgagaagtgg gacatcattc tggtcatgaa gatggaccgt atacaccgca
    47641 actccaagaa cttcatgata atgatggaga atctggagaa gtgggggaag aagttcagct
    47701 cgatgagcga gtcgctggac acctctaacg ccgtcggccg cttcgtggtg gacatcatac
    47761 agaggatagc gcagctggag agcgagcaga taggcgaacg cacgtacatg ggcatgaggc
    47821 agaaggctga atctggccag gggcttcttg gttttcgtgt cccgtatgga taccggctcc
    47881 gggaaggtgt gcttcacgtg gatgagaccg aagctgaagt ggtccgctcc atatacgaaa
    47941 gatatctgtc tggacagacc atggagatga tcgcctgggg cttgaaccgg gacgggataa
    48001 ccacccgcac tgaaggagaa tggaccgtct ggtcgatagg gcggatattg cacaacccag
    48061 tttacgcggg atatctgaga tgggaggacc tggtaaatcc ctctcctcat gttccgatca
    48121 tcagtgtccc aaccttcaac aaggtacaga tcgagatatc tggcaaggtc aagaacaaaa
    48181 agcacgcttc tgtcaaactc ttacccgaaa attgaaaagt ggtatccaga tcattgaaaa
    48241 ttacattgta aacggtaact gggtagacaa aaatataggg gcttatacac tggtttgaga
    48301 atatatataa ttattccaaa attaagccag ttaagtggta ggtccatcat ttgatattta
    48361 acggcatata ataaaatcca tcaatactgg gcaattcaat aagtttatat tatctagtgc
    48421 aacggatacc ataaacagga ttgtgcgaac aatccatagg ggacagtccg aagggagagg
    48481 ggatcacaac atgggagaga cattaccaga ttttatgggt gggtctgaaa aaggcctttc
    48541 cgtagcagtc tgggcataga cctcgtcctt tctttatgtc cacaaaaagg agagattgaa
    48601 atggcagaag aaagcaacgt acatatcaag gtagccggtg cagaggtatt gggtttgctc
    48661 ctgatagcta tgatcggcgt cctgatagca atgtatggtt tgggtatgtt cgacaccctg
    48721 tctgtgattg ccggggtggc cggaaccatt ggagtaggaa tgctcctggt tacgatcgta
    48781 gcatatctca atgagaacat tctggtttcc gcagcgttcg gcctggtagc agttttcctg
    48841 atgggattcg tcgggatggc tactccggtc ctgagcggtg tgcccgaggc caacttagcg
    48901 gctgagtact acaccatctt cttcggtatc ggtctgatac tgataggtgt tgtggccttc
    48961 ggccagccga tcaagatact gcccatattc ctgttgatcg ctggtctctc agtactgctg
    49021 ctgggactgt ggttcgacat gggtgaggac ataaggatgg tcgttggagt cttctggctc
    49081 atcaccaccc tgatggctct ctacatggct gcagcgatcg gcatgttcgt ggtcaaggga
    49141 aagatggtcc tgccgctgtt ggtcaaggcc taagcgagga ttctcataca aacccaacaa
    49201 accctttccc aattctaatt tttacaaaga ttgaactcca cccatggtca ttgaccgttc
    49261 atgaccggtg accgtgcccg atggtgctgt gaagatctga acgaagcgat cgagctggct
    49321 gccaggcgaa ataagcaggg cattcggtgc ataatcgatc ccctggggga actggccaag
    49381 gatgatgcgg catccgataa agccctcgcc gaggccatcc agaccatcga agcgatatcc
    49441 accaacggtc tgcatgcttc ggtggcctta aaaccgaccg cgctcggcgc ggcctatgat
    49501 cacgatggtt gtatgaaaag agccagggaa ctggctcggc tggcttggaa agatggcata
    49561 gatgtagagc tggacatgga ggcccgtaag tacgtggacg atactctgca catggccact
    49621 gagctaatga gcacgggaaa tgggcagatg agcatcgctc tccaggcgta tctctatagg
    49681 acgccaatgg acgccaggag tatgaacatg gccggtgtga aggtgcggct cgtgaaagga
    49741 gcgtacgccg gcgacctggt cgacttcaat gacgtggcta ccgccatgct agacaacatc
    49801 gatctactag cgacagcggg aaggccgttc agcataggca ctcacgatcc ccgggtgatc
    49861 gaacggcttt ggaagaaccg ggccttcaag ggactgatag aggtagggat gctcaaaggg
    49921 ctcggggatc agacgaaggt caagctagcc gggaagggtt ggtcgatcgc cgagtacgtt
    49981 ccctacggca gggattcctt cgcttacatc gcgaggcgag agaactatgt tcggaacctg
    50041 agcaagttag ggttgcaacc ggttccgtaa aagggtaata accccctttt cttttgttaa
    50101 cggggtatat ttttttaagt atcgattttc gccgttaaac ccagcctaaa gaaccggttt
    50161 tgacccttcc caagttgatg ttagggagtc cgtcgcatac aaatttgaac tggtgtgtac
    50221 aatagactat caaaacacat cataatattg taaataatat atacaatagt attattgaaa
    50281 tatacattta caatattact attataaact actataccat tagtaaacat taaactatat
    50341 gtagtaatag tactatagtg attctaatgt cagatggaaa gacgacgata caattgagcg
    50401 aggcgaccag ggaccgactc tacaaattga aattccgtcg gacctatgat caattcctga
    50461 acgagctctg tgatctgtac gaggcagagg agaagaaagt acagtaaatt ggctaaaaaa
    50521 cctattcata ttgctattaa attaattaaa atatgtagtt tagctacata ctaaaataat
    50581 atataattat agtatacatt gattattttc atttttttat cggttccaac tgagataaga
    50641 aggattatta agtcggttgc tcccatagca aacccagtga tctattcatg aaggcaagca
    50701 ttgagaaagc attgaacgac cagataaacg ccgagatata ttcggcctat ctgtacaagt
    50761 ccatggagat gtacctgcaa tcgatcgacc tgcctggaat ggccaactgg atgaacgttc
    50821 agacccagga agagctggca catgctgaag gtatgatcca gtacattaat gtccgaggcg
    50881 gccgtgtttt actgaccgcc atcgaagctc cgaagaagga gtggaagtcc ccggctgagg
    50941 tatttgcgga cgcctatgat cacgaagcga acgtcgtcac agtaaagata cacaagctgg
    51001 tagatctggc catcaaggaa aaggaccacg ctttcaacca gttcctgcaa tggtacgtgg
    51061 cggagcaggt cgaagaagag gacaacactt ccactctgct gaggaaattg aagaaggtcg
    51121 gtgaccacac gcccagtctg atgcaggtcg acgcgcagct cgctgccagg gtcttcaggg
    51181 ctccggtaat tccaggtact acagtgggcg gaccttaaaa aaactcaaaa ggcaggggga
    51241 aaaccccctg cgattttttt taaaaaagtt tacggaacca gaaccttgtt gaccacgtgg
    51301 atgtatccgt tccggcactt tatgttgccg cggatgatgg tcgcaccagc gatcttcaga
    51361 agtcccttgg cgtcgactgc cagttccttc tggtcggccg cagccacggt gggcttggcc
    51421 atcaactggt cgtaggagaa tgcgccctcg accacatggt gcgtgagcac ggccttcaac
    51481 ttggccttgt ccttcaacag cgcctcgacc gttccgtcag gtagatcgat gaatgctgag
    51541 ttgttaggca cgaacaccgt gaacgggccc ttctttccca gcaggtcgac caacccagct
    51601 tccttcagtg ccgcaactag tgtcttgtag tcgtcgtctg ctaccaccgt ctcggcgata
    51661 gtcttcagat tcgggtctgc gacccaagat cccttcttct tgagaaaatc aaataatccc
    51721 atataatccc tggacaccga tttgacttgt atcaatataa aaccatacta ttaacgcgat
    51781 aaagtttcct attataagtt ataaatataa aattaaaaaa acaatttttt atgagccttt
    51841 tcaataaaac gcgaaagata tttataatcg agtagaacgc gacctacgag ctcaggacaa
    51901 atgctatttg tttagtaaca tgctaaataa atataatcgg tataactata acataataaa
    51961 atatagtaca atcaaaatga ttattataat actcaaaaat taaacattat ttttcatcat
    52021 tcaattcaaa tatgttaaag tcaatatatt ttctaaattt cttaaataat ggagggattt
    52081 gggatgcaaa taaacaagct gagagcatca gcaatagctt ggatactgtt ggtgcccttg
    52141 ttcatgggat tgatcctgat tacggatgtc gacgccacac cgacacccgt tctcgacgaa
    52201 atctcatgga tgaagggggc catcgatagc cattcggatg taagcaatat tgtgagtcag
    52261 gcgatagatg gcgacggtca cattcacgtc agctattaca attcggacac gaatagacta
    52321 atgtacgcca ccaacagtaa cggcgtttgg aggtcacagg tagtcgattc gacaaccagt
    52381 gccggcaagt ataactccat agctgtggac ggggacggag ttgtgcacat tagctattca
    52441 aacgacgcca ataacgacct caagtatgcc agtggtaatt tcgactcatg gacattgacc
    52501 acggtggatt ctgccacagc agtcggcgat ttcaattcta tcgcctgcca tgataagaaa
    52561 gtcttcattt catactataa ctactcgggt caatctctta agttggcggt caagacggca
    52621 ggcagatggt ccacaaccac catcgtcgaa gacgtctctc aaggcagcac tatggccatg
    52681 aaagacggga aagtgtacat cgcctacctt tccagcaact ttaagctcaa gatggcaatt
    52741 ggaaatggga caggatgggt cgttcaggat gtggattcta catcggcttt cagcaagtac
    52801 ctggccatag acatactgaa tggataccca tgcgtagttt actatagcac catctctcaa
    52861 gatctcaaga ttgctaccac atccggcacc gcatgggaca ctcaagtggt ggacgacgtg
    52921 acctccgtag catatggggt ttctgtcaac gtcgactctc tacaaaggat ccatattgta
    52981 tactcagatg ccgcactgga cctgaggtac gcaatataca acggtacctg gaactatttc
    53041 attctagatg ccagtgttgg taatttcaag tcgatcgtat cagatgtgaa tgacaagcaa
    53101 catgtcgtgt acatcgaccg tgaacccacc tactaccagc tgggctacct tacaaattct
    53161 ggagcaaagt ggctcataaa ggacatcgac tcaagcgggg gtgcagacaa attcagctcc
    53221 atagccgtgg acgctatggg attcgcacac atagcattct atgatactta tgtcgataac
    53281 aacgtcacga agggaaggct ttgccacgcg accagtgcta atgggtggca ggtagaaaca
    53341 gtcgatatat ctgcttcagc ggtgcccaac catccctctg tggtcgtaga ctcacacgga
    53401 tttgtgcaca taagttattg ggatgctgct atcggcggga cactaaagta cgctaccaac
    53461 gctgacgggc cctggaaaaa ctacacactg gacgctctgg gcaacatagg taagagcact
    53521 tcgatcgctg ttgatagcac gggtactgtt catatcgttt acacttacca cactcccaat
    53581 cctgccaaca acgtgctgaa gtacgctaac ttctcttccg aagctggcct aaataccggt
    53641 agtatcgaga ctggtgtcgt caccaacggg caggtcgctc ttgtcgctga ttccgaggac
    53701 cacctgcacg tcgcctacta caaggaaggg gagctccact atgcgataaa gagcggggcc
    53761 acctggggcg atgctgagtc ggtcgacacc tctgatcagc ttggtggcgg aatatcaatg
    53821 tacgtaaacg cagccggtaa tgttttcata acatactatg acaacggtct gagcaaactc
    53881 atgtatgtga acaatactgg tgggtcgtgg gtatctcagg atatagccct ggcagctggc
    53941 ggcgctagcg caatattcgt tgacgaggag ggtgatgaac acatttccta tctcgagacg
    54001 aacaccccca acgggatctt gaagtacaaa gaacgcagga acggcatctg gatggatcag
    54061 aacatagacc taaccggatg ctcgccccaa atttccatgg ccatggattc cctcggtcgg
    54121 gggcatgtaa gctactttga tcccagcacc aaggtattga agtacgccac atctataatg
    54181 gcgccatctg cacccaccaa tctgaccata gatgttgaga gcaataagct aactctgaac
    54241 tgggccgcac ccaaggtaga tggtggatca tccatcatcg agtaccggat attccgctcc
    54301 gtggcgggtg gggaatacct ctttttggat gcggtgcttg ctcccggatt agcgtacatc
    54361 gatgatggtc tggaggacgg tgtgacttac tcctactaca tcagggcggt taatgccgaa
    54421 ggtacaggtg aactctctga gttcgtttcc ggaatccctt gcagggagcc tcaggcgccg
    54481 gtgctaaagg cctctggtca ggacaaggcc gtgaagctca cctggaacga gcctgaaaat
    54541 ggtggcgcgg atatcactgg atataaaata tatcgcaaga acgcgaccgg tgtgttcgag
    54601 ctattggtgg agctgggcgg aaacacccgg tcctacaccg acaagcaact ggagaacggt
    54661 caggagtact cctattacat aaaggcgttc aacccggccg gacctagtgt cgatagtgcc
    54721 gttgcttccg ccacacctga agagtccaac actctaatga taatcgccat cgtgattatc
    54781 gtgctggctg ccgtcggagt aggtgcgttc gtcttcctta agaagagcgg tcgaatctaa
    54841 gaacgagggt cccaaccctc ccctttcctt attttcattt ttccctccct cagttttatt
    54901 accaaggcgg tcattgtgaa gaccgatggc tgacgattgg accgagctct accgccccca
    54961 ggggctttct gaagtggtag gcaaccccaa ggtcatcaag gacctccaac agtgggcggt
    55021 ttcctgggag gaaggtcgcc cggagttcaa ggcggtggtt ctaatgggac cacccggcgt
    55081 gggcaagacc agcgccgcgc tcgccctggc cagggacttc aaatggggag tggtggagat
    55141 gaacgcctcc gaccagagga acgcggacgc catcaagaag gtggccattc gcggttcccg
    55201 ttccgaaacg ttcaacgacg agggggagtt cctctccagc aaggatgggc acctcaagtt
    55261 gatcatcctg gacgaggcgg acaacatatt cgggcgcgag gactccggcg gcataccggc
    55321 gatcgcggaa ctggtggcca agacccggca gccggtcatt ctgatagtca acgatttcta
    55381 cgagctgagc cggaagagct cggccatcaa gaacaacacc ctgcagctca aggtatccaa
    55441 ggtgcaaggg gcgaccatgc gcaacgtgct gcgccggatc gctctggacc aggagctgga
    55501 agtgccgcat cgggtgttcg agacgatcat cgagaactcc aatggggata tgcgggcggc
    55561 cgtccgcgac ctacaggccg tcggcgaagg caacgccaat atgggcgagg acgatgcgtt
    55621 cgtgctggaa agccgcatgt ccattaggag catgtacgac ctgatgcgcg acatcctgca
    55681 cgaatcggat tcccggaggg cgcggcgcac ggcgatggac gtcgatgaga cgcccgagca
    55741 tatcatgatg tggctggatg agaacgtccc tatggagtac aaggaccccg aggacctgta
    55801 ccgggccttg acccacctgg cacgttccag tactttcttg gccagggtca ccaggcgcca
    55861 gtactatggt ttctggtcct atgccaacga tcacaacgtg atgggggtct gctcggccaa
    55921 gtcccgtccc tatcgcggct gggtgcagta ccgtttcccc agctacatca tgaagatgtc
    55981 ccgcagcaag gccttccgtt ccatgaagtc cgggatagcc agcaagatat cagagcatac
    56041 gcatacctcg acccgccgct cggcgcagga cgttcttccc tatttcattg agatgttcaa
    56101 ggccgatccg gagttccggt tgacgatgat caacaccctt cgtctgaaca ccgaggaggt
    56161 ggccttcatt ctcgataaga aggtcgattc ctcggaggtc aagaagctca tgctggaatc
    56221 ggaaaaagcc aaggcgtcca tggagcccgt tcccaagtcc atcccagagc cggtcgagga
    56281 gaaggaggag aagcctgagc gaaggccgga gccgaaggga aaacaggcct ctcttttcga
    56341 gtactaggtg taacatgaag gacgacctgc gggagatatt gcagaagcag cagtaccggc
    56401 tgtgcggcga tcacgcgggg gttaagttat gccactggat gaagcagagc ctactgaaag
    56461 ggcggacctg ctacaagcag gacttctacg gcatccgttc gcaccgttgt ttgcagatga
    56521 ccccggcggt gaacgattgc acgcacaact gcctgttctg ctggcgggtt cgtggctttg
    56581 aatcgacggt caccaagtgg caggaccccg agacggtgtt ggacacctgc atcgaggggc
    56641 agaggcagct ggtcaccggt ttcaaaggtg atccaagatg ctcgccggcc atgtgggagg
    56701 aggcccgtca accacgacag gtggccatct ccttggccgg agagccgacc atatatccct
    56761 atctggggga tttcatagaa ctatgccaca ggcggggaat gaccaccttc ctggtgacga
    56821 acggaacgtt ccccaaggtc ctcgaggaac tttcggaact gcccacccag ctctacgtga
    56881 cggtggccgc gcccaataag gacatctaca agaagctctg cgtgccgcag atcgacgacg
    56941 gctgggagcg attgatggag acgctggagc tcttaccatc gctcaacacc aggacggtca
    57001 tcagacacac cttggtgaag gactggaact tgggctggga gaaggagtac gccgccctgg
    57061 accgcaaggc cgaccccacc ttcgtggaac ccaagggatt cgtgttcgtc ggcgattccc
    57121 gtcggcgaat gtccatggac aacatgccct cccattccga ggtcctggag ttcggtcgcc
    57181 gggtggcgga cgaactgggc atgtgcatgc ttcgtgaaaa gtcagatagc cgggtggcgg
    57241 tgttcggaga aagcggcacg gacaccaaga tacccggtct ggatcagagc gagtgagcgt
    57301 tcagccactt tagtatggat gagcagcact tgtcggccgg gatgttgtgt ccggcgccag
    57361 ggacccatat cagctccgcc ccttcgatgt ggctcgccag ctcggtggcg aagtgcgggg
    57421 cgaccatgat gtcctcgtcg ccatggatga tgagcgtagg ggcgattatc ttgtccagca
    57481 ggtcgtggct gtcaaagagg tccagggcca gcttctgggc cttgaacccc tcggcggcgc
    57541 gcttaccgtt cccgttgcat ttccgctggg ctggtttcga caatgccaat ttcttgaagt
    57601 aatcctcggg gaggcaccag gactgcatga ggtccatcag cgaatcgaac gtcgccccct
    57661 cgtccaccgt gcgtatcatg gtgtctatgg cgaacgagga gcgctccggc ctccgggtgt
    57721 aggtggacat cagaacgagt gcgcctacct tctccgggtg gtctatggcc acccgctggg
    57781 ctacgttccc tcccatggac catcccaata cgtgatagcg ctggtgaccg aggtgctcca
    57841 taagcccggc gacatcgtcg gccaaggtgc tcatggtgaa cagggtgggc ggataatcgg
    57901 tctcgccggc accacggttg tcgaagacca cgacctgatg cgatctggac aggagaggca
    57961 cgtacttctt ccagaaagct atctccccgc ccaggccggt tattaggacg atcggctccc
    58021 cttccccgtg ggtctcgtaa ttgatgcgcg cgttcccgat ctcaacctta ggcatcgaac
    58081 ggcgggatta ggctggtgct atttgtcatt tatctctaac ccgtcaaggg aggtggctga
    58141 gcaccttctc gtcgaagatg tacttcttgc gtggtcccac cagatacacc ggtaaccttc
    58201 caaagaggtc cgtgcggtag atgtcgtaga gcatcagtgc gtagtattcc ctggtcacct
    58261 gaagcatggc gtcgcagcgg gccaggtcct cctccgttcg gctggagatc tcgttagccc
    58321 ttgccattag ctcttgaagt ttatcgatct tgttgtagag cgcctggttg gccgtgcgca
    58381 ggctcatcat gctctgaaag gtcctcatga tccagaactg ctcgatgaag atgccgatga
    58441 acagaaggac atcccagatg tggtattcct tcagggaggt caccaaggtc aggaacgtgt
    58501 acgaaggcag caccatcgcc gcggtgaaga tgatggctag gatgagaagc accgccaccg
    58561 ccgccgcctt taccatgaac gaggccgctc tgcctttgag cttggccatg cctatccgcc
    58621 tcttccatga acgagctata tcggtcatcc cctgggtctg aggctccagg aagttgacca
    58681 gggagtagaa gatgaatatg agcaccacct gaaagatcat caggttggcc agaccggcaa
    58741 cggccttgta gtcggtgagt atgaagccaa aaaggactat cattcccgtt ccaagtatga
    58801 gcgtgaaccc cacggtcaga ggcaccattc tgcctaagaa gacggttatg agaatctcca
    58861 cggtcagttt gggcttgttg agcaatctcc ggtaggccag tttcctttgc tccttgctct
    58921 tcttctgcct gaccacatta ccgctgttat gtaccacctt ccgggtggtc ggtaggagca
    58981 agaacaggaa gttccaggaa tagagcacca ggccggagat gaaccagctc cagagggcct
    59041 tggggtacag gaagatgaat actccggtaa aggtcatgag catcaagggc aagatcgttc
    59101 ctcgccactg gtcctttcgc tcatccttga ccaggtccag caggtcctgt tgccgggcca
    59161 gttcagcccg ggattcctca gagaagtcga ggacgctgtc ttcgaaggtc aggaccgaag
    59221 gttgctccat gctcccgtgc caagatgact gggaatctta aaaacattcg cacctgttcc
    59281 caaggatgcc ttgaaccaaa gtccaagaat ggaaaaggat atctaatcca ttctggcata
    59341 gatgcccgag gtgttccttg ggaaagaaag agaaaatggc ctcgatgctc catctggtcg
    59401 gtggaaagcc ggagaacgtg gaaaagatcg tggacgagat cgacatgttc ttcgacacca
    59461 tgaacgcgga gctggaggac tggaagttgt ccatggagga attccccgac ggcactcgca
    59521 tatacgcccg ctttcaggtg ctggtcaaga aataggtgtt gaaaatgccc gaggaagagg
    59581 aggcccctcg cgagagggtg ctgatgtgcg ccgccgattg gaaggaccct gagtgccgta
    59641 cggtgatcgg ggagttccac aaggagggca tcgatgccga gattttagac gtagacttgg
    59701 acctgcaggg cttcgagaag gcctggggcg acaaaggcca ggccaagttc cagagcgagt
    59761 accacaagga gggcgctcct tatctgggag aggatggact gaacctttac gttcccatcg
    59821 ggccggtcga acgcacgggg cggtcgccca aggacgcggt gctgaaccgt aaattggacg
    59881 tcggaacggt ggaggtcatc acctacgctc ttttccgggc catattcggc tacggggtga
    59941 acgttcccat caagcgtccc ggcgtggtgg acatggacgt gaccatcaag ggtaaggaca
    60001 tcaacgtgaa caccaacgat ttcttcttca acgtgcccga tctggtggtt tggaaggtcg
    60061 tctactcgca tcagggaact ccgataatgg agttcggtcg cggggtggac aaaggtttca
    60121 aggtgcaccg tctacaggcg cttaaactgt tcctggccct ccgttccaag tccaagaggg
    60181 ccaccaaggc gcgtatggcc gcccgaaagg cggccgccga gaatgacgat gatgaggaag
    60241 taaccaaggg gacgagatga tgagcccggt acaagatgat cagagggagc atttccggga
    60301 cgtgctgcgc tccatacatc tcatcatggt cgaatcgttc aagctgagac aggtcaaggt
    60361 caccccgctg ggttcggagg ggtcccggct gtccataccg ataaagatcg aaggggtgga
    60421 taggaccggc tctccggcgc gttatttcgc caagattctg ggcggcagcg acatcatgac
    60481 cgagaagacc atccagttct tcaagaacgt ctatctgcag atggagggac gttcgccgct
    60541 cttcaacttc aaccgttccg ccaaggacct ggccttgcat cagttcgaga taatgagcca
    60601 ggtctaccgt ctgggaatac ctacggccaa gccgctaggc accttcgctc ttcccggtgg
    60661 catgtggttg ttcgtggcgg agttcctgga ggcggcctcg tccgcgacca agaaggtctc
    60721 cgaggcccag ctggataagg cgttcgagca tcttcgtctg atgcacaaga acggcatcta
    60781 tcatggcgac atcaaaccgg agaacttcct gttcgccgat caggtctata taatggacgt
    60841 cgggaacttc ctgaaggacg ccccggagaa ggaaaagctc tcgtatgatc tggcctgcgc
    60901 tctggcctcg ttcctggacc tggcgtcgcc agagaaactg gtcaagctgg cccgaggata
    60961 ttacggcgtg cgggacctga aacgtgcggc aggctatctc gagcttatcg accgtcggcc
    61021 agattttaaa atggcgccag agaagatgaa aaggttgatg gagctgctgt cctagtcgga
    61081 ggccttcttc ttgaacaggg ccttggcggc gaactccact cgtataccat ccttcgtctc
    61141 ctccaccgag aacttccact gctctatgtt ggcgttgtag tccttgaaca gcttcttcag
    61201 ttcctggcct ttctcgttga gaaccacggt tacgtccttt tcgggcatga tgattacacc
    61261 tgtgggcgga actatggcag cctgggatag attaatgttt ggggtcaggc gtccggccat
    61321 agcgtggcgg acatctccct gagcttcatc ttcatgatct tcccactggc ggtcatcggg
    61381 tattcctcca cgaaatgcac gaacttgggg atcttgtaga aggctatctt cccccggcag
    61441 tggtccatga tgtcctcggc ggtgagcttg acgcccgggc gcaagaccac gaatgccgct
    61501 ggcagctccc cgtacttgac ggagggaacg ccaaccacct gaacgtccgc cacgccgtcc
    61561 atgtgatgga tgaagtcctc cacctccttg ggatagatgt tctcccctcc gcggatgatc
    61621 atgtccttga ggcgaccggt gacggcgtaa tatccgtcct cgtccatcat cccgatgtcg
    61681 ccggagtgga gccagccgtc cttgtctatc gccttcgccg tctcctcggg catcttgtaa
    61741 taccctttca tgacgttgtg gccgcggcag cacagctcgc cgtgtttacc cggacccagg
    61801 tgctccccgg tctccgggtc tattatcgcc acctcgatgc ccgggaaggc ctttccgacc
    61861 gtggagcact tcttctccag gctgggttcg tcgtagcgtg tctgggtcat ggcggggctc
    61921 gattccgtca ggccgaagac tatggtgacc tcccgcatgt tcatgcgttc cacgcactcc
    61981 tccatggtct tcaccggaca gggcgatccg gccatgatgc ccgtgcgcag ggtggagaaa
    62041 tcgaacttgt cgaacagctt gtggtccagg atgccgatga acatggtcgg cacgccgtac
    62101 agggcggtgc atcgctcctt ctcgatggac atcatcacgt tgatcggatc gtaacgttcc
    62161 aggatgacca tggtcgcccc gtggttcagg caggccatta cggcaagcac acagccgaag
    62221 caatggaaca gcggaacggg aatgcagacc cggtcagcgg tggtgaagtt ctcgttgacc
    62281 ccgacccagt aaccgttgtt cgtcagattg aaatgggtga gcatgacacc ttttgggaat
    62341 ccggtcgtcc cggaggtgta ctgcatgttg accacgtcgt acgtggagag ctcgctctgc
    62401 ctctgacggt aatcatcgtc cgaaacggcc acgctcattg ccagtagctc gttccaggaa
    62461 tacatgccgc gatgcttctc cggtcccagg aacagcaccc gtcgcagatg cgggtagcgt
    62521 tccgagcgta agcggtcgcg aggctgggtc ttgagctccg gaatgagctc gtagagggtg
    62581 ttcacgtagt ccgtgtcgcg gtagccgtcg atgacgaaga tgttctcgca gtccgactgc
    62641 ctcagaaggt aatcgatctc cgctgaacgg tagtttatgt tgatggtgag taggatggcc
    62701 ccgatgcgag cggtggcgaa ctgcagggtc acccaatgcg gcacgttcgt cgcccacatc
    62761 gccaccttgt ctcccttttt aacgcccagg gccatgaggc ccttggccgc cttgtccacg
    62821 gtctcccgga actccctcca ggtctggcga taatcgcggt ccgcgtagac cacggcgtcc
    62881 tggtccggaa cgacgtcaac gatctcgtcc aggagctggc cgatggtggc ctctcgggtg
    62941 atgttctccc tcggcatggt cccacctcag atcggagtat agatgacggc gaatatttcg
    63001 gccgcctctc cgttcgccgc gcccaggtga tgaggtacca cggagttgta gtgcatggag
    63061 tctccctcct gcagcaggtg tctctccttg ccatagacca gttccacctg ccctttgacc
    63121 actatgacga actcctctcc ctcgtgcgag gaggtggagc agtcctcgca gggctgaacg
    63181 attatgtaca gaggctccat gtggcggtcg gtcttcccct tggccaatgg gtaatagtga
    63241 tacttgccga ccgcgccctc cttatgggcg gcggtctcct ccgcccggtc cttgaaacgg
    63301 gttatgaccg ggtccgggcg aaactgatcg tccataaagg tccccaggcg ctgtccgagg
    63361 gcccgggaga ttttaaccag cacgcctagc ggggggtaca cctctccctc ctccgcgtta
    63421 cgcaccaagc tcgcatcgac gccggcgttc atggccaggt cctccacgct catgttcaat
    63481 ctctcgcgat aggtgcgtat tcgcgtgcct agtttgtcag gagtggtcat acggtcatcc
    63541 tccggtcgtc caggccttaa gccctggtcc gtaatggcca tacctaaacc gccgagcgtt
    63601 taagaacctt actttttttt atcaggcccg cgatcaaaaa agaaaaaaag gggttggcgc
    63661 cgaagcgcga tcataggttg ttcttcgccc agtcgaaggc cgccctgtag accttgcggt
    63721 tcctctccac cagggccggt ttcgttgcaa agctggcgtc cagggcttga agcaccttgt
    63781 cctccgggag cccatgcagt cccagggcgg taaggccccc cagcaaagcg gtgttggcgg
    63841 ccttcggcgt acccgcctcg gctgccaatc ttgaagcggg gaaggccatc acccgaactc
    63901 cggcccgaac ggtgggcttg gggagcgagg cctcgtagat caccactcct ccctccggta
    63961 cggtcatgga gaacttctcc gcagctggct ggctcattac gaccaacacg tccggtgcgt
    64021 caacggtggg cgaccccacc tcctttccgc tcacgaccac cgagcaggaa gcgtagccgc
    64081 ctctctgctc cggcccataa ctagggagcc aggagacgaa gcgcccggag cctccggcgg
    64141 cctcggcgac gaccaatccc agcgaaagca cgccctgccc tccgaaaccg gagaacttga
    64201 acttacgttc cttgaactgc ccatccacct tggccgatac gccctcatgt cccttgccca
    64261 gcagctcgtc gaccgtcagc tgcggtatga cgttggccac cggcgccggc tcggcgctgc
    64321 ggtcccggaa gttacctagc gggaacacct tctccatatt ctcgttcacg aactgggcgg
    64381 aggccacggg gtccagacgc cagttggtcg ggcacgggga taggaactcc acgaaggcgt
    64441 accccttccc gtccctttga acctccagcg ccttgcggac ggccttcttg gcctgcatga
    64501 tgtgcttggt atcggaaacg gagaccctct cgatgaacac cggggcctcc agctggttca
    64561 gaacctcgca aaccttgagc gggtagcctt ccttcaccgg gtcgcgtccg aatggggtgg
    64621 tggtggtctt ctgcccgatc atggtggtcg gggccatctg tccgccggtc attccataga
    64681 tggagttgtt gacgaagaag caggcgaagt gctcgccgcg gttcgccgct tggaaagcgt
    64741 tattgaaccc tatggctccc agatcgccgt ccccctgata ggagatcacg accttgcctg
    64801 gaagcgctct cgtgacgcca gttgccacag cggacgcccg tccgtgcggt cccgcgacgt
    64861 tcccgcaatc gaagtagtgg aaggagaagg cggcgcaacc gaccggcgtt acgaagaccg
    64921 tgcgatcctg gatgccaagc tcggccatgg cctcggcgat cagcttttgg atgatgccgt
    64981 gaccgcagcc cgggcagtaa tgagtggcgc gagtacctgg ttccttgcgg tcgaacgttt
    65041 cgtagaatcc ttgggccttc ttgatcacgc tctcacctcc agcatctgcc gggcgcgaag
    65101 gaccacgtcc tccaccttca tcacgttccc gcccatgcgg ttcagcagtt gaacttcgca
    65161 tttgatatcg cggtccaggt ggagcagcac atcgtcccgg tactggccgt tgctaagttc
    65221 cacgaccagt atctttccgg ccttggccac ttcgttcagt gccttggtcg ggaaggggaa
    65281 cagcgtaagc ggccggaaca ggccggcctt gatcccctgg gaacggagct ggtccaccgc
    65341 cgagcgggcc acccgggagc tggtcccgta accggtgagc actatctccg cgtcctcggt
    65401 ccggtaggat tcgcaaagga cgtcgtcctg catggaagcg taacgttcct ggagcatcca
    65461 gttgtggcgc tcctgaagct cgttgtccag gtatatcgac gaaacgaggt tgcctcgggt
    65521 ggcggcgtcc ccttgaacgg accaggaggt ctccggtctg gcggacacct tttccgggag
    65581 ctgcaggaac tccatcatct gtcccagcac ggcgtcggcc agtacgatcg ccgggttgcg
    65641 gtacttgaag gacagttcga acgccttgat ggtcaggtcg cacatctcct gcacggaggc
    65701 gggagcgagc acgatgctgt gatagttgcc gtggccgccg cctctgaccg cctgattgta
    65761 atcgccctgc tccggtccga tgttgcccag gccgggccct acgcgttgaa cattgacgat
    65821 gaccgccgga agctgcgctc cggccaggta ggacattccc tcctgcatga gcgatatgcc
    65881 cggtccggag gaggcggtca tggtgagctt tccggtcgcc gccgcgccga acatcatgtt
    65941 gatggcgccc gtctcgcatt cggcctgcag gtgttccctt cccaattgcg gaaagtactc
    66001 cgcgacggca tgcgcaatat cggaggccgg ggtgatcgga tagccgaagt aggtgtcgca
    66061 gccggcgtac accgcgccta tggcgaccgc ttcattgcct ttgacgaact tcctcattgg
    66121 gggtccctcc cgtcgtccac ctggagcgcg tacggttcgg ggcaattgta gaagcaggcg
    66181 gcgcagccgg tgcatccctc gcccaggtac tccacggcgc tgtagccacg gcggttgatg
    66241 cggcccgata ggcgcaggac cttcttggga caggcagcca cgcagcggcc gcagcccttg
    66301 cattcgttct cgtcgacgat gggacgggag atcctcttct cggtgctcat cgactatctg
    66361 gatagagggt cgatacttaa aactaattca acctcgttcg ttccgtacac tggctcacag
    66421 gctgccgtac cttcgcacat gctcccaggc ctcgtacagt tcggggtcct tatccggtcc
    66481 atcgtaaagt cccaggtcct ttcgctcgaa cagcctgcgg tcctctccca ccgggcagac
    66541 cttgatgcag atgccgcatg gcgaacggta cttcttcttg agggaaatgc tgcgtcccgt
    66601 gcatcttttc ttgtcgatcg aggccttcgg ataatccaca tcccctatcg cctcgaccgg
    66661 gcaggcctcg atgcaccttc tgcaccgtac gcagaggttt ctatccatcg gcttcccagg
    66721 ggatatcttg gcggtggtga agaccgagac gaagcggacc cggggcccga actccctggt
    66781 gagcagcatg ttgttcaatc cgaacgtacc gagcccggcc aggtaggcgg cgtggcgatg
    66841 tgagaagaag gcgtaggggt tgtcgaccag aacctccacc gaaccgtagc cgtcccgggg
    66901 aacgtagaca gaggcgtgtc ccaggcggtt caggagctcc gagagctgat aggcgcgttc
    66961 gtccaactgc gcgttcaggt tcttgtacag ctcctggtac cagatggacg gtgaggtctc
    67021 cagtatcgga agcgtaactg gaagaccgag aaccaccacg gtacggcatc cagggaatat
    67081 ggccttgggg ctgaactccc ggggcgggaa cggaacgaag ggcggatcgt cccaatcgtc
    67141 ggcggaggcg aagccgacca tctctatgcc ccagtcccgg caacggtccg tgatcttccg
    67201 gcgaaggtcg gcgctcatgt tgaagggaag gccatcgaaa atagaaatat ctgcgccctt
    67261 caacttctag tcagacgttc ggctacccgc tcggcgaact ccctggtccc cagcgttccg
    67321 cccaggtccc gggtgcggtc cccttcggtg agcgtctgca ccagggcgga ctgcaaccgg
    67381 ctggcggcgt ccatcttctt caggaactcc agcatcagac atgccgatag tatcgtggcc
    67441 gagggattcg cgatgtcctt accggcgata tcaggtgcgc taccatggac cggttcgaaa
    67501 agaccgaaac ggtcgctgag gttggcggaa ggggccattc ccaatccacc ggtgagcgcc
    67561 gcggcctcgt ccgataggat gtcgccgtat aggttcagag tgacgatgca ctggaactgc
    67621 ttcggtttgg agatgagggc ggcggccacg gcgtccacga tcatgtcgtc cgcttccagt
    67681 ccggagtcct tcatcacctc gtagaacacc cgacggaaca gtccgtccga cttcctcagc
    67741 acgttcgcct tgtgcacgca ggtgatcttg ttgaagccca ttacccggga gaccttgatg
    67801 gccttctcta cgatgcggcg gcagcccttc tcgctcacca ccctttccag gatgaccgct
    67861 ccgtcctcct cgcgttcccg gccggtgtac attccctcgg tgttctccct cacgatgacc
    67921 gtgttcaggt cgaccaactt gtactccggg agcatgggga agcagggacg gatgttggcg
    67981 tacaggtcaa aatgcttgcg cagctgtagc agcggcgatc gatagccagg gtcaggcgtc
    68041 accggcgagg ttatggctcc gaagagcacg gctttggagg actcaagggt ccgcaaggtc
    68101 tgggcaggaa gatattcgcc cgttcgttcg taacagttca gtcccatgta ggccttgacg
    68161 aactccaggt ccaggtccat ctgttccagg atgctcatgg tggcgcccac cacctcggga
    68221 ccgatgccgt ccccgcccat caccgccact cgggtcattt caatcgctct acgatggaag
    68281 ccaccaaaat tggaagggtt atcgtcgcgt cgccctccac gttcacctgc caggcgtcct
    68341 cacggacctt tccccaggat atggcttccc gcacctgcgc tccgctcagg gagccgtcgt
    68401 actccgtcgc ggtggtcatg tagacggcgt aatcaagacc gccccggaac tgattccacc
    68461 agatgacgtg gtgcttggag atccctccgc caatgatcag tgcgccactg gcctcggcat
    68521 ggaagaccag gcttgacagt tcctgctcgt cctcgaacag gtctatcttg aggtcgcggt
    68581 gggtctgcca gtacatccat atctggctgc cgaaggagcc atcggtgatc cctggaacga
    68641 agataggtat cttgttcttg tgggcccagt agagcaacga gtcctcattg tccaatcggg
    68701 cgccgacctg gtctatgatc tcccgggtgg atatggagct ccttccggcc aggatctcct
    68761 cgaacatggg gatcaagcgt tcttcgagca ccagcccata gctctcgtcc gggacgagaa
    68821 cgttgcctag gcggttgtaa ccttcctcgc gcagctcggc gtcgtccata gcgaagtcgc
    68881 cgtgatagta atgcttccag gagcgggcga ggtcgtggtc gagggtgccg caggtggtta
    68941 tcaccacatc caccagctta cgcttgacga gctctacgat cactcccctg gtcccggtgg
    69001 ccatgatgca ggccgggaag gacaggaacg taaggcactt ctcgtccttg accatcttct
    69061 ccacgatgtc cgtggcgtca gccagtttct tggcggtgaa cccgccggaa tcggacatgg
    69121 cccggaccag ctgatcgacg gtcatgccct cggtgacctt gatgtcgcgt accgctctct
    69181 cttccatgat gatcgtccct cctatccccc gcggctagaa atatattgcc ttgaaaagcc
    69241 gaaagtgaaa ttgtgcaagt ccttaatatc aaaccaaggc cttgtactgg caatggacac
    69301 caaacgcctg gcggtgctca gcggcggtta catcggaccg ctctctggca atgccgtgct
    69361 ggccatgata ccggtactca agacggactt cggggcgagc gcggaggaga tactggtgtc
    69421 cataaccttc ttcatgcttc ctttcgtcat cttcaatctc ttctccggca cgatatcgga
    69481 tgtctacggc agacgcaaga tgctcacctt cggctttctg atctacgccc tgggatgctt
    69541 gttctgcgtg gcgagctccg accttatgac cttctacctg tcccgttccg tgcagggcat
    69601 cggctacgcc ttcgtcaacc cggtgctgct ggccatactg ggggacatga cccctccgaa
    69661 cgaacggggc aaggtcatgg gatacttcgg ggctttcacc accgccggca tcgccaccgg
    69721 ccccatgata gccggtttcc ttaccgagta tgactggagg tggatgttcg tactggtggc
    69781 cgtgctggcc gtggtcgtga acttctggat aaggtccgcc tgcccggttt cccgcaccaa
    69841 cccagaagca ttgagacacc tgaagagcaa cgtaataacg gccgtgacca gcaaaggtgt
    69901 cggcaccctg tgcctgttgg gattcctgac cttcctctgc tacatgggcg ccctgggttt
    69961 cctttccgac catctctcgg tcccgcccct ctcattggac gaggggacca ttggactgtt
    70021 gatcggaatg agcggagtgg cgggaatggt cgccgcgccc ttgggcggtc gcctggtgga
    70081 cgccaaagga cgcaccttca ccgccagcgt cggtttcgcg gtggtcggac tctccctggc
    70141 gttcctgtac ctgtcgtccg actggatcca tttcgccggg tcgctgctgg tgctagggac
    70201 cggtaccgcc ttcatctggg catcgctatt gacaataacc gtggagatag ttccccagct
    70261 caaaggtacg gtatcatcag tgttcaacag cactcgtttc ttcgggtact cgctggcgcc
    70321 tctcattttc gcgccgatct attccgtcga cggtttcgga gcggtgctgc tgataggtat
    70381 cgctctgacc ttggtctcat tcccggtggt gttctggttg ggagctcaat tgagggcgtc
    70441 ccagtccgat aataccaatt tcagctgaga ccgggtgttc tccaccgaac cgcagttgtc
    70501 cagcaccttc cagccgcggg atgagaggtc cagcaccttg cccctgacct tctccaggga
    70561 cctcaggttc tcgaacatct cccgctcgtg ctcccgctcc tctatgcggc gcagagcgca
    70621 ttccgggttc acgtccacca gtaaaagtcg ctcgggtatc ggaagcacct tgcagaagaa
    70681 ctcgtaccct tgccggtaga gcggtgtcgg aagataggcg gtggccatga tgtaacggac
    70741 gaagatgacc ttgtcgtggt ccttccagcc gcgcaatcgg cgcagggagt tcagaacgtc
    70801 aagtatgaag aatatggtgg ccacggtgcg catcatcttt ccctcggagg tcagcgacct
    70861 gcggctgagg cgtccgtaaa atgaatcgga tgggtgctgc ctgaccagga ccttctctcc
    70921 ccgggagcgg tagtgttcgg ctatccactc ggccacggta ctctttcccg agccgtctat
    70981 gccgtccacc actatcagtt ccatctcatt acctcagata cccgccagga acatgatgag
    71041 cgccgtggac aggggaatga ccagattgtc atattcgcca ggggtgtaaa gctccaccac
    71101 cgatacgaag gcacccaatc ccagagcggt cagcgcactg atcgccagcg gtatcgatct
    71161 cgtgccgtac agcccctcgg tgaagaggag gttatagaag ttgattatta gaaatatagc
    71221 tagagcggcg aacacgaata cggcaagcgt tccttccagg gtcttgttgc cgtggatctt
    71281 ccgcttgccg aacgtcttgc cgaactgacc gcccaggccg tccccgtagg ccatgcagac
    71341 gatggccacg gaggcgacca ccaggtcgtt gaaggcgaag aaggccaata aggcccagga
    71401 gatcgcatag tataccagac ctagcttgtg accgtcatgt gaggcggtgg ataggatgga
    71461 ccccttgagc tcgcctatca gcttgctgtc gtccttctcg cgcctccctc catacttcga
    71521 gaagatgtat agcaggggta tgaacggtac ggcggccaag agcgacatca cgtaattggt
    71581 gtcgaacacc caccagaaga gggcgatgtt gccgatcatg acgtgaatga acttgcggtg
    71641 gaacgagtgg tcccgcagga accgccaacg gtcggtgatg accaccatga cgcccacgta
    71701 aacgtagacc aatatgagtc cgagagcgtc accgcctatc aaagcaatct cacccacatg
    71761 accttaggca atataaaaaa atgagagagg ttttatcctc tcaacgactg gcaatattgt
    71821 ccgttaaacc atagatcacg gcgtccatcc ttctttatgt taacatatga aataatatag
    71881 ttcaatcatt gaaaaacatg tgccagtcca cggatttcgt gattgggatt tacctaaacg
    71941 atttatatag gtagccgtat ttaggcagga atttaaaaga ggctttcaat gctagacgat
    72001 cctctgtact atacaatacc gatcgcgggc atcataggtc tcctcttcgc cggttatctg
    72061 acctggtgga ttctcaagaa ggacactggt actcctgaga tgaaagccat cagcgacgcg
    72121 atccgcgaag gggccatggc ctaccttgct cgtcagtaca agacgattgc catcatcagc
    72181 gtcatattgg gtatcctgat cactgtcggg atcaacctgt ggaccggtgt ggccttcctg
    72241 ctcggggcat ttttctccgc cctgtccgga tacatcggaa tgtacgtgtc tgtgagctcg
    72301 aacatcagga ccgcgagcgc cgcaaggcgc tccttgaacg aggcgctcct gacctccttc
    72361 cgcggcggcg ccgtctccgg catcgccgtg gtggcattga gcctgatggg ggtcgccggg
    72421 atattcttcg tttaccaggc gtatgtggca gtgggcccgg ccgattcggc caccctttac
    72481 atggacgcgc tgttccttgc cgttggatat gccttcgggg catccttcgc cgcgctgttc
    72541 gcccagttgg gcggcggtat ctacactaag gccgccgatg tcggcgctga cctggttgga
    72601 aaggtcgaag ctggaattcc cgaggacgac ccgcgcaacc ccgccgtcat cgctgacctg
    72661 gtcggcgaca acgtgggaga ctgcgctgga cgtggcgctg acctattcga gagcactgcc
    72721 gccgagaaca tcggcgccat gatcctgggt atcgctattt tcgccttcac cggaaacccc
    72781 ggttggttca tgttccccct tgtggtccgc ggattcggtc tgctggccgg cctggtcggt
    72841 atcatgaccg tgcgcatgaa gaacgaggac gagaacccga tgaaggccat caaccgcggt
    72901 tactacgtga cgtgcgtcat cgccgccatt ctgttctaca tagctgtgga ccagttattg
    72961 gccggtgaga tgctcttctt cgtctgcggt ctggtcggta tcgctctcag catagtgatc
    73021 gtctacatca cccagtacta caccgctggc gaatatcgcc cggtgaagaa gatcgccaag
    73081 gcctccgaga ccggcccggc caccaacatc atcgctggta tctccatagg tatggagacc
    73141 accgccatgt cggtgatggc catcgctatc gctctgatag cctccttcga gctcggtgtc
    73201 atggcctcgc cggacgccgc ccacgagttc atctatggtc tgtacggcac tgccgtggcc
    73261 accatgggta tgctcgccac ctgcgccttc gtgctggccg aggatacctt cggtccgatc
    73321 actgacaacg ccggcggtat cgtcgagatg tccggacagc ctgaggaggt ccgcgtcagg
    73381 accgacaggc tggactccat cggcaacacc accaaggccc tgaccaaggg atacgccatg
    73441 ggtgccgcgg ccctagccgc ctacctgctg ttcggcgcgt tcttcgagca ggtcgccaag
    73501 atccgtgggg tcgacattct ggccttctac gacagcttca ccgtggacct gctccaaccc
    73561 gtggtcttcg tttccgctat gatcggcgcc atgctggtct acctgttcac ctcgctagcc
    73621 attagcgccg tgggcaaggc cgccgggaac atgatcgaag aggttcgccg ccagttcagg
    73681 gagcggcccg gcatccttgc cggtactgag aagccggact acgccacctg cgtggacatc
    73741 agcaccaagg gcgccttgaa ggccatgatc ctgcccggca tactgccggt cgtggtccct
    73801 gtggccttgg gacttactct gaggtacgct taccctgaca acaacgatat cgctgtcatg
    73861 ggcgtcggtg ccttcctgat ggtcgctacc atcgccggag tcctcatggc cctcttcctc
    73921 aacaacggtg ggggagcctg ggacaacgcc aagaagtaca tcgagtccca gggtaagaaa
    73981 ggtacgccgc agcacgctgc cggcgtggtg ggagataccg tcggagatcc gttcaaggac
    74041 accgccggtc cctcgctcca cgtgctggtg aagctgctgt cgaccatcac cctggtcttc
    74101 gccgtgctct tcgtggtctg agcaaaaccc ctttccatca tttttctttt ttatccagca
    74161 tgctgaaagc ttatatgctc ggtgctcaat ctttatataa gagatttatc atgccaagtt
    74221 agttaagagg attcctcatg tatatgttga cccaaaggga aaaggttgtc cgcataccgc
    74281 ccagcagatt gggcgatgac gtggacgaag tggtcaatga gctggcccgc gagtcctacg
    74341 aaggtaagat cgagggagat gactcgctca ctgttatgat ccagaacatc gaaccggtcg
    74401 gcgaagggcg gatcgtgcac ggcgacggtg cggtctacca atcggtaaag ttcgattccc
    74461 tggtgttcaa gccattggtc aacgaggtcg tggaagggca cgtatgtgag gtcctgaagt
    74521 tcggggcctt cgtgcgcttc ggaccattgg acggtcttct gcacgtgagc caggtcatgg
    74581 atgaccgcat ggacgccgat gaacagaatc agaggctcat aggcaaggac accaagcggg
    74641 agatcaggat cggcgacatc gtcaggacca ggatagtcac cctctccttc aatgagcgca
    74701 acccccggga gagcaagatc ggccttacca tgcgtcagcc cggactgggc aagaaggaat
    74761 ggatcgccga ggaccgggcc aagaaagggg gtcaggagaa atgaagggag tagtaaaggc
    74821 ctgcaaggtc tgcttcgcca taactgaaga ggacaagtgc ccgctctgcg gtggggaaac
    74881 ctccaaggac tggcaaggct acgtggtcat catagaccac accaagtccg agatcgcaaa
    74941 gaggatgaac attgacaaga acggtaagtt cgccctcaaa gtgcgctgat ctggacgtcc
    75001 cctccaaagg gtggaggatg ccggacagca tgaggggcga actaggcatg ccattcggaa
    75061 gcctgttcag gggcgaggac gttcttgaag cgctttccga ctgcggtatg ctcatcacgg
    75121 tgggggacgt ggtctccagc acttttataa acaaaggtgt catcccccat ttgaccgttt
    75181 acgaccggcg caacgaaagg aaggagctgg aggcggggga acatcccgcc gatctccttc
    75241 aggtgccgga aaccaacgtg gagaaccctc ccgggtctat aacccccgga ctggtcaagg
    75301 ccatgaagga tggcctggag tccccgggca agaccaaggt gagggtcata ggagaggagg
    75361 acctggccgc gctggtgtgc gccgccatag ccccggcagg ttcctgtctc gtgtacggtc
    75421 tccccggaaa gggagtggtg ttggtccata ccaacgccaa ggtaaatcat gcggcgcaga
    75481 atctgatacg ctcaatggag gtattgaagt gaagatcgag atcgagagca aaaagcccaa
    75541 cgccctgatg gaccgcactg aagtcaactt caaggctgat catagcggag agggctcccc
    75601 caagagggcc gacgtgaagg cgaagctggc ggaggtcctg gcggtcagca aggacaaggt
    75661 cataatcgac cacatggaga ccgagttcgg aatgggcgta agcaccggct acgccaaggt
    75721 gtacggcagc accgagtcgg ccaagaagtt cgagaagaac tacctgcagg ccaggaacgg
    75781 gctcgctgag gctaagaaga ctaagaagaa gtgaggtgtg atccatggct gctccaaaga
    75841 agaaagaggt caagaaggaa gccccgtcgg caaagaagga ctactaccag gccaagggcg
    75901 agaagctgga acggttgaag aagagctgcc ccaagtgcgg gcccggcgtg ttcatgggcg
    75961 agcacaagga ccggacgtcc tgcggcaagt gcggatacac tgagttcaag aagaagtgag
    76021 cgcgtctcga tcttcccttc ccgcgagggc gggtaaatgg gtcttggtgt tccaatgacc
    76081 gcgggcctgt agtgtagctt ggatatcact ggggcttccg aagcctcaaa ctggggttcg
    76141 aatccccaca ggcccgcctt aaccctcaaa atccaacatg ttcttattaa ccgattctat
    76201 tgtccctggc atgcaactca cctccgaaga gcaggatatg ctggccggaa aacaaggcaa
    76261 ggccaagcgt aaggccatgg agctcttggt ggcactgggc gccatctacg gagccgatcg
    76321 tctcataccc atcacctccg ctcatctctc cggcgtttcc tacaagacca tcggcgaggg
    76381 cggcatcgac ttcctggagg agatggcggc cgacggaaag gtgtgcgtgc cgaccaccct
    76441 gaaccccatg ggaatggacg gcgagcggtg gaaggagatg ggcgtggacg agcatttcgc
    76501 ccagagacag atgcatatca tctccttgta cgagaagatg ggcgtggagg tcagctgcac
    76561 ctgcactccc tatctgctga ccaaccgtcc caaggtaggg gatcatatag cctgggcgga
    76621 gtcatccgcg ctttccttcg ccaattccgt gctcggggcg cgtaccaacc gggaaggggg
    76681 gccgggggcg ttggccgcgg ccatcaccgg acgcactcct aactatgggc tacatctgga
    76741 ccagaaccgt aaggccaccc acgtggtggt agtggagaag ggaataacca aggacgagtg
    76801 gtccctggtc ggacactccg tgggacgcaa gttgggagcg tgcattccat tcttccgcgg
    76861 tctcggcagc gatgtcaacg ggttgaaatc actggccgcg gccatggccg ccgccggttc
    76921 cgtggccatg ttcatggtgg agaaggccac gccagaacag ccagatactt tggaggggtt
    76981 gccggtggtc aatatcaccc gggaggacat cgaggatacc gttaaacgtc tgcgaaccgg
    77041 caagaagccg gacctgatag ccataggctg cccccacctc tcggaaagtg agatgaagga
    77101 gctggcagat ctcttggacg gaaagaagaa gaagggcgac gtggaggtgt ggttctgcac
    77161 ctcgaaaggc atatggctgc gctgccccaa ggagagggcg gtgctggagc gattcggcaa
    77221 ggtgctgtgc gatacatgca tggtcgtggc gcctatagag gttggtcata aggtcacggc
    77281 aagcgattct gccaaggcct gtgcctatct acccgggcta tgctcgcaga aggtgttctg
    77341 cggttcccgg cgagaactaa tggagttgat tttgtgaagc tgaagggacg tgagatatgc
    77401 aagggcaagg cgatcggacg attactgatt ctggacgagg ccttcagctt cctgggcggc
    77461 gtggacccca agaccgggct gctgaccgtg gcctccggtc gagaaggtga gagcgtagac
    77521 aatcgaatcc tggtcttccc gtatgggaag ggttccacgg tcggttccta taccatcatg
    77581 gaactgaaga agaacgggca cctgccggcg gcgatcgtga acgctcaggc cgaaacgatc
    77641 gtggccaccg gagctgttat ggccggggta ccgatgatcg attccattga catatcgcta
    77701 cttcgggaag gtgaccgggc ggtgatcgtc ggcgacggac ttgatatgat ggacctagtg
    77761 gagaagaagg tggtcacctg cgtgctgcgc cgaaagggga agatactgct gctcaaacgt
    77821 agccaaaagg tcgggaccaa taagggtaaa tgggccgcgg tcagcggtta catcgagagg
    77881 ggggagaaac cggaggagac cgccttgaaa gaggtggacg aggagaccgg gataacctcc
    77941 gcccgcttgg aggccatggc ggaaaggcta cgcatccgcg acggaaccta cgtctggagc
    78001 gtctatccgt tcctgttcga ggtggccgac gagaaggtca tcctggactg ggagcacacc
    78061 gagtgcgcct gggtggaccc tgcggagctg gacggctatg aaaccgttcc cggttttcgc
    78121 aaggtcctgg aagccctggg actataacgt cccatcaatt tccttttcca gcaggttcag
    78181 ctcgttggcg tcgatggtgg atgggttcag caccatcatc atgatggagt tgtttatggc
    78241 cacctggtcc ctcagcgact ggacgaagcg caggacggtc aggaagttgt tgttggtgat
    78301 caggtactcc aacccatcca gcaacaccac gccctgtccc ttggccagga actgctcgag
    78361 cgagtagctc aacttctcca ggtccttggg gcgaaggctg tcctccttgc ccacgttgct
    78421 cagccaaacg atcggcgttt caccaaggtc gaacttgttc cgtatcttga ccggatagtt
    78481 gcgggtgatg cagaacccac gcttacccag cttcagctgc tccatgaaaa gttcgtatga
    78541 acggtcagag cgatcgtcct ttatgaggta gctataacca tcttggaggc cctgggcctt
    78601 tggcgcctcc gtttcctcct ccgtcacctc ggcgcgcaga gaagccccgc aggctggaca
    78661 gttcagttcc ttggcggtta cctcatgtcc gcacgtcgcg caggcggagc atcgttggaa
    78721 gcccccatct gacacgtact tcagcacctc atcgatggtc ttgcttccca ggccgggaac
    78781 gttcttaaga gcatccttat ccgcggcctg cagtttatcc agtgagtcgt aaccggcgtc
    78841 gtacagcatc tccgccttga cctcgttcat gcgcgggatg cgcagaaggt aaggggtcat
    78901 ctccgaccga tccatgatct tgccggagcc ttccggtacg gccttgcata tctcagcgga
    78961 gcggtcggtg tagtggagcg ctttgcgcac ctcggccttg gaaagcttgg tgatatcttc
    79021 gatcctatct tcaccaagtt gtttcaggtc cgcttcgttg cgaacgccag cgtccaccaa
    79081 tgcctcggcg gccttggggg ttattcctgg gatcttggta agctccttta tgggatcccg
    79141 gaggttcata gaggagacac ctatctccac cttctccccc tctatctccc atttgccgac
    79201 ctgttcgccg tgcacctcaa agaccagttc catggatttg gaacggacct cggacatgat
    79261 gtgcgatttc cacatcttta cgtattcggc aaccttggta tcggccagaa cttccacttt
    79321 gacgaactct tcgacgtcca gcttcatctc cttgcgggtc tgctgcaccc ggcggatgat
    79381 ctccctggag aagccttccg cctctatctc gcgggtaacc tcgaagtcaa ggtagatctc
    79441 gcctccgctg aacgtggcgg cgtaaatgtc cttcggcagg gagacggtga aggagaccat
    79501 attgggctcg atcttcacca gttgtccctc tatgcctaac gagtactcgc cgcgttgcat
    79561 gctctccttg ataagtccgg ccggccggct ttgtaatagc accgcgatct tggaagccca
    79621 ttgacggtag accttcccga tggccatggg gttcggtacc acgttcagaa tggtctccga
    79681 ccactcctcg cccgtcccaa cgtattcgat ctccttgacg ttggcctggg acttcagtat
    79741 gctctccagg gcgcgtaacg agatcagagt gtcattactg tccaccttga tcacgatcct
    79801 cttcataggc cagcgcaact tgacgttctt gagctgcctt tccctggtga cggtgtccac
    79861 gatctcctgg accatggcca tggccttttc caatcgttcg tccaccctgg tcaggtcgct
    79921 gctcggccag tccatcatgt gcacggtcgg tttggaaccg tccatgtgtc gatagacctc
    79981 ctcagcgaga tgcgggcaca tcggtgccag aaggagcgtg gtgtccatga tggcgtcgaa
    80041 caaagtgcgg taggcggcga gctttccgac gtccccctcc tcgctccaca tgcggtccct
    80101 gatcagcctg acgtaccatc tcgacaggtc gtccaagatg aactgctcca atgcccttcc
    80161 agccttgtgc agctccaggg cgttcacctg acgggtgaac tcgttcttga gcttctccgt
    80221 gcgagatatg agccagaggt cctcctggtt gaggtgggcg cgaaccgttt ccttggtgat
    80281 gcgctgcgcg tcgaaatggt cgatggccat gtaggtggtg gcgaagttga ccacgttcca
    80341 gaacacgttc aacgtcttgc gggcgttctt gacgccctcc atctggaacg ggatatcctc
    80401 ccagggggcg gatgtcttaa gcagatagaa gcgcaaggcg tccgccccgt gctccttgat
    80461 cacctttccc ggctccacga cgttgccctt gctcttagac atgggctggc cttggctgtc
    80521 caacatccag ccgtgcatga gcaccgattc gtaaggcgcc cgcccgaaag ctatcacgcc
    80581 ggccgccaat tgcgaataga accagccgcg cgtctgatca tgagcttcga cgatgaactt
    80641 ggccggccac agccgctcga aggcgtcccg cttcttcggg aatcccagtt gggcccagga
    80701 ggctacggcg gaatcgaacc acacatccag gacgtccggt acgcggctca tcttgccacc
    80761 gcacttcgga catgcgagct taacggagtc tatccagggg cggtggagct ccatatcttc
    80821 cacgtaaccc tcggcgccct tcagctcgtc caccatgcct accacccgca tctcgccgca
    80881 ggagcaggtc cacaccggga tgggtatgcc ccagtatcgt tggcgggata tgcaccagtc
    80941 gcgggcgttc atggtccagt cgtactcgcg ggaggaaccg gcccagtcag gggtccagcg
    81001 aaccttctct atctcctcca gcatctggtt ctttacctgg gtgactcgca ggaaccactg
    81061 gtcagtggtc ctgaacagaa cgggtgattt gcagcgccag caatgtccga aacggtgctc
    81121 gatggtgccg ctgaagaaca ggcggtcctt ctcctccagg tccttgatca ggtccggatt
    81181 ggccttcttg atatgcatgc cgacgtactt gctccctacc agtggggtgt atacccccgt
    81241 ctcatcgaca gggcagaacg gttcgagccc gaactcctta cccagctcga aatcctcggg
    81301 accatggccg ggggcgatgt gcaccagacc ggtgttggaa gcctctacgg tcttggaggg
    81361 gagcaccttg tgcagccatt taccggtggc ctgcgtttga tacggaacgt cgtccacgaa
    81421 gggggtgatg tattcgacgc cgaccaggtc atctccctgg atggtctgca ggacatcgta
    81481 cttctcccag ccaccgaggt tccttatctc ctcttccagt cccttcatga tgatgatggt
    81541 ctcggtgacc cccacctttc ggtagcggac cttgacgtac tcgaaatcgg gatgggccgc
    81601 cacggccagg ttagcaggca aggtccaggg ggtggtggtc catatgagca aggatacctt
    81661 gggatcgtcc ttgaggcgga acttcacata gatggagggg tccttctcat cccagtaatc
    81721 tatctccgcc tctgccagag cggtctcgca gcgcggacat cccggaagca cccggctggc
    81781 gcttatcagc agacccttat cgtacgcccg cctgagcgtc caccaggccg cttcgatata
    81841 gttgggggcg atggtgagat acggtttctc ccagtcgaac cagacgccca gctctttgaa
    81901 gtcggcgttc atctgcttct ggaagtccag ggcgaagttc ttgcaggtgc tgacgaaacg
    81961 gtcgataccg tacgcctcga tctccttctt gttcttcacg ccgatggact tctcgacctt
    82021 gacctcgatg ggaagcccgt gcatgtcgta gccgggagta tcgctcacgt tgaacttctg
    82081 catgcgtttg aaccggacga tcatgtcctt gatcgtcttg ttcatggctg tgcccaagtg
    82141 aatgtatcca gtggtgtacg gaggaccgtc tacgaaatag aagtccggac cggaggcccg
    82201 tagttccttg gtcttcttgt acgcctcggt ctctgcccaa agggcctgga ccgatttttc
    82261 aagcgcgctc ggattgtaat tgccttggac ctgctttatc atcgccgtcc ctacaggccc
    82321 ttatcagaca acttcctatt aaactagttg gtcctggcta tgatgaacgt catcgtcgaa
    82381 agggctcaga acatgtcaag ccgcatttgg tccttcttac ccgaggagaa cttgtccagc
    82441 gccccgttca ccctcttctc cgaaaatccg tattcgccgc atagcatgtc cagcacgctc
    82501 tggcggtccg gtgacctcca cgccaatcga tagtcgtcgg tacgctcgaa gtccaggaag
    82561 atcgatcgca ccttctccat ctccccctcc tcaagaccca gggagcgcaa ggctccggcc
    82621 agggtgccat actgctttat gagcttcagg gccttcttcg gtccgatgcc catgaccccg
    82681 gggttgaagt ccgtaccgac caggatgcaa aggtccacca gctgctttcc gttcaggcct
    82741 aggctggaga gcgtctcgtc acggtcgatg atctgcatgc gcacctcgcg atattcatcc
    82801 tttccaggca tctttcgcct tcccgagagg gtcagatttc gcaccagtcg cggcgctccg
    82861 aagagaagcg agtcaaagtc ctgcgaagct gatgcccaga cgtcgccctt ggcgcacatg
    82921 taggccgctt gggcctcccc ctcttccggg gcttgcacga ccggaattcc caggtgggtg
    82981 agcaggatgc gcgaagattc cactatctca ttggttatgc gcgaggactg ggtcgccttg
    83041 gagtaagcct tcctcacgtc accctcggcc ttggcctgct cccactcctt cttggcggat
    83101 tcccttctct cccgccgttc ccggatggtg gcctccttct tttccggggg gatcccatca
    83161 aagacgtaag cggaccgcaa tcccatctcc gccaggttgg cgttgcgatt gagcaagccc
    83221 tccaggtgcg aagtgatcct tccccggggg tccatgagcg gggtcccgtc cggctgacgt
    83281 atcaccgaca ggaactggta aatggcattg taggcgtcga tggccacggt cctccccatg
    83341 aggttctgcg tctccaggtc cttggccaga actaggtcgg ataggttcac gcccatagcg
    83401 atcgaaagtg gtatcgctct cggccataaa gctattgtcc aagtggcgaa tgattttgat
    83461 atgcgtgacg agcacgccga gcctgaaagg aagccggtga ccgaaggcca gatctacgag
    83521 gtgaagataa ccgatatagg agaacgaggg gacgggatag gtaagataga aggtctggtg
    83581 ataatagtcc cggataccac gacgggagag acggtcaagg ttcgcatcac ccgggtggag
    83641 aagaaggttg cgttcggaag gcggacctga tcaatcttcc gccttgggga tgtagagcat
    83701 ggtaagccct attcccagcc acatcaaggc cagtatgatc acccagatgt tcggggtaat
    83761 tatcaaagcg gccaaaagga acatcagggg ggcgatgacg gtgaggaata tcaccatttg
    83821 ttttcccgac atcttcatgt acattgcacc ccggattgcc gacctttcga tatgaacttt
    83881 cctgcgctca gtccagttcc ttcttcttgt tcacgaactt gatgccggcc caatcctcgt
    83941 ccaatgagga gatcttgacc tcggccatgc catgcccggt accgatcgag cgaacggtca
    84001 ctccgaccag gtcggaatcg atctttgagg acgttctggg gtaggatatc cagatgatgc
    84061 cttccttctt cagggcgcgc atgagcttgg ggaactcccg gcgaagctca tcctccgagg
    84121 aggtgaacaa ctggatgaaa tccagttcgc tgtccccgct gccggcctcg accacattct
    84181 tggggaggcg cccgagggcc acatcgtact tggaaggggc gtttattatg cgtatccttt
    84241 ggccttcctt tatccctaac ttggccacca gtgatttctt agaacctatt cgcgccatga
    84301 tcggaccatt cccgtgatat gtagagccct atcgtttaaa tacgacaagg tttgccctag
    84361 attccgcttc accattatta tacttgctat tgaaaaacag cctctagtac atgtgccaaa
    84421 gatcgatctc cgccgccatg tccttggcct tgaacagggc ggacccggcg gccagtacgg
    84481 tcgcgccgtt ctccacgcac agctttccgg tctcccggtt tatgccgccg tctataacta
    84541 tctcgaaatt gagcttccgt tcgtccctga tccgacgggc ctgcgatatc ttcggcagca
    84601 cctccgaacg gaacgattgc ccgccgaatc cgggctgcac ggtcatcacc agcaatagat
    84661 cgatatcgtt gaaatagggt tccacggtcg atagttcagt accggggttg agggatatcc
    84721 cggccttcat gcccagccgt cttatgtgcg ccagaactcc cttgacatca tgagtggcct
    84781 ccacatgtac cgtcaggtaa ttcgcgccgc attccgcgaa gcgctccacg taacgctcag
    84841 gcatctcgat catcaggtgc acgtcaaaag gtatcttggc gtgggggcgc agggccttga
    84901 tgacttctgg cccgatggta aggttgggaa cgaacacccc gtccatgaca tcaatgtgga
    84961 tccagtcggc ctgggccgcc tcgacccgtc gtatctcctc gcccaggcgg gcgaagtcgg
    85021 cggaaagtat cgatggagct accttgacca ttatgagacc tcggaacgaa ctggagatgt
    85081 tccccttgct aaaaaaactt tggattcatc tagcagcttg agatgccagt gggtgataag
    85141 ttgatccgat cagggggtgg atgtttcatg cggacgccat cagaggcgat gtggggcgga
    85201 cccctatctg gtgcccaaag gagttcccgt cctatggacc accccatcct cgcaaggagc
    85261 aatcctatta tatccataag gggggttcca ggtccatggc ggaagctcgt cacgctatta
    85321 aggtcagcaa gacctgcgat gtcaagggat gcagttccga ggctgaacgc tccatctccg
    85381 gggatgcggc caccgaggcc aagctcaaag tggaagatgg tatgaagcgg gttcacctat
    85441 gcaaggaaca ctaccgagag tacaagaagg tctcccgcaa agaccgagag ctgggatccc
    85501 ttggcaggtc gttcggcaaa tagtaatatc ctttgaggat tccccgggat catgaaggca
    85561 ggctacatcc agttgctctc cagcgccgga ttgtccggcg cagctctgct catccccaac
    85621 atgttgaggg acgatctggg cgccaacacc atggagatcg gcctgatcac cgcctccttc
    85681 aacctcgctc ttttcgcttc gtcctacata tttggacggg cgtccgacgt gcacggacgc
    85741 aagctgtacc tgcagggcgg tctggcgttg acggccatcg cgcttttcct tctggtattt
    85801 gccaacagca aggagaccat agccgtggtt cgaataatga tcggactatg cgcgggaatc
    85861 tatccctcgg ccctgctgac ctatgtctat gagaccgagg ggaagatagg caagttcacc
    85921 gcctacggga gcctgggctt cggcatcggg accttcattg ccggaatttt aaccatctac
    85981 tacgagatat tcctggccag cggaataatg ttgctggtgg cctatttcat ttccacccgc
    86041 ctgatgttcg tgggggaaaa ggtgcaccag gtaccgctct ttccggtggc gatgatccgg
    86101 cacaactttc cggtgtacat atccatcatg ttcaggcaca ccggcgccaa tatgatatgg
    86161 gtggtgtacc cgctgttcct ggcggacctg ggggcgaccc ccttgttcat cggtgcggtg
    86221 tacggtgtga acgccatcgc tcaatacgtg ttcatgcgct acatagaccg gttcaagacc
    86281 tatcatctgg tcatggccgg cttcctgttc tccataatca cctttccatc gtacaccctg
    86341 gcgacccggc cggaggagat cctacccatg caggtgtcga tcgccgccgc ctggtcctgt
    86401 ctctatgtag gttccattaa gtacctcatg gagaggaacg aggagaaagg tacgtcgtcc
    86461 ggcctgctgc agtccttcct gagcatctcg gccatcatcg gggcgctggt gggcggggtg
    86521 accgtgttcg ccctgggcta tcacggcgcg atgtacatag ctacgatact agccatccta
    86581 ggtttcgtgg tgttcatgat cggaaataga ttcatgagcg gcaaggaaaa agggattata
    86641 gctcccaagg gggtctaggg aggcatggac ctcacattcc tgggaacggg cggaagcgtc
    86701 ccgaccacca agcgtaacac cgtttccata gctttacgtc tgggtccgga ggtcctgatg
    86761 ttcgattgcg gcgagggcac ccagaggcag ctaatggcct cctcggtctc cttcatgaag
    86821 ataaccaata tcttcatctc ccatcatcac ggcgatcact tcctggggct accgggactg
    86881 atccagtcca tgaacttcta cggtcgggag gctcctctga acgtttatgg gccgattggc
    86941 acgcaggaga tggtgaagac catactgcgg ctgggcatat tcgatcgcaa gtacgaggtg
    87001 caaggtcacg atctcgcccc gggcgaggtg gtcatcgggg atggttacca ggtcgccgcc
    87061 ttcaaggcga accacaccac tcccgcccta ggctacgctt tccaggagaa cgaccgcccg
    87121 ggtcgtttcg atccggacaa ggcgaaggcg ctgggggtca gggaaggccc taacttttcc
    87181 cgactggtcg aaggctattc ggtacaggtg ggctcttcca aggtcactcc agacatggtc
    87241 atggggccgt cccgaaaagg gctccggctg gtctatagcg gggacaccgc tgccagttct
    87301 gaacttgatc aagcctgcgt tgacgcggac gttctcatac acgaggccac cgtagcttcc
    87361 gacctggagg ccaaggccag ggagttcggt cacagcacgg ccaaggacgc cgctctcctg
    87421 gcaagggatt ccggggtggg ggcgttatac ctcgtgcata tcagcggacg atacgaggac
    87481 gttgacgttc tactggaaga ggcgcgcgga atattcggac ctacgacgat acctaatgat
    87541 ctggatatgt tcgttctgcg tacggaccga taattctttt aagaatatcg ctcacagcat
    87601 cttgagcagg tcggccgagg ttatgatgcc ggtcatgtcc ccgttccgtc ccaccatcac
    87661 cgcgtgggag ctgctgagca gagcggtcac cgcctctatc ggagtgtcct cgttgacgat
    87721 cgggaatgca tcctccatta tgtcgctcac cttgagctcg acgatggtct ccatcctttc
    87781 cccgtccctc aaacgtgaca gtatctggtt ctcgctgacg ctcccaacat gctggcgtcc
    87841 gaggaaaact ggcatctggg atattccaga ggaacgcata agttcggtgg ccgccttcac
    87901 cagttcgttg gactgaactc caactatctg cctggtggcc aggtcgcttg ccttgctggc
    87961 cttggagtga cggcgggatt cctcgcgaag ggcatcgaat aatttggtga ccgcttcgta
    88021 actgcccctt aggctccccc tttccagctt ggcgatggtg gattgactga ccccgctgag
    88081 cttggccagt tcctgctgcg tgatgtcaag tgacttgcgt agccgcttga tctcaccctc
    88141 cggagggaac ttcatgtttg gaccataaga ttattcatat atgaatattt gagtcaatca
    88201 cccttatatc aagccatgat tttccctgtt ccatccaggt tccattttat ggttcctgct
    88261 cacaaaaagg tgaactattc atggctaagg taagcgcgaa ggcgaaggcc accgccaaga
    88321 cggtgggccg taaggtttcc cctaagaaag tatccaagaa catagtggtc gagagcatga
    88381 gagcaactcc gctcgcccag cagaacatcg aactcgtgga gaggaagggc atcgggcatc
    88441 cggacagcat ctctgatggt atcgccgagg ccgtgtccct ggcattgtgc aagatgtacc
    88501 tcgagagatt cggagagatc ctgcatcaca acaccgacca gaacgaggtc gtgggcggtc
    88561 agagcgctcc caagttcgct ggtggagagg tcctggaacc gattcacatc atgctatccg
    88621 gacgtgccat cacccaggtc aacggtgagc ggcttcccta cagcaccacc gccatcaacg
    88681 ccaccaagga atacttaaag cgcttcccta acctggatgt caaccgccac ataaccgtgg
    88741 actgccgcat cggtaagggt tccttcgacc tgatcaagaa cttcgaggcc ctcaaggacc
    88801 agtgcaagat ggacggccgc ggcaaccact gtctgctggc caacgacacc tccttcggat
    88861 gctccttcgc gccctactcg gacaccgagt tggtatgtct ggagaccgag aagtacatca
    88921 acggcgccat gaagaagaag ctcaaggaga ccggggagga cgtcaaggtg atgtgctccc
    88981 gcaacggtaa gaagatcaac atgaccatcg cctgcgccat ggtcgaccgc tacgttccag
    89041 acgctgacca ttatgcaagc gtcatcgagg agatgcacga gcgggtcctg gacaacgcca
    89101 ccaagtacac cgattacgac ctggccttgg ccatcaacca cgccgacaac ccggccaccg
    89161 gtaacttcta tctgaccgtc accggcctca gcgccgagaa cggcgacgac ggatccgtcg
    89221 gtcgcggcaa ccgcatgaac ggcctcatca ctccgtaccg caccatgtcc atggaggcct
    89281 cggccggcaa gaaccccatc acccacgtgg gcaagatgta caacatcctg gccaactgga
    89341 tcgccaatga catcgtcaag aagagcaacg gcaacatcgt cgaggccgac gtgcgcatac
    89401 tctcccagat cggtcgcccg ataagcgatc cagaaacctg cagcgttcag ctgttcctgg
    89461 cccctggagc tgacgaggcc aagtggcaga aggaggccta cgccatttcc gacgagtggt
    89521 tggagaacat caacaaggta acggagaaag ttgtaaaagg acaggtcacg gtattctgaa
    89581 gcatgaagct cgtcgacctg ccccgctacg gtccggttca ccgattcggc aaccatcacg
    89641 tctaccgcac gctgatggtg ctctcggacc agaaacgcaa aggacgtaag cagatagcgg
    89701 aagcggtggg catcggcgaa ggcagcatgc gaaccataat cgaatacctc cgtggactgg
    89761 acatgatcga gatccatcaa acgggcgtga agatcacccg ccacggaaac gccttcctat
    89821 ccgacctgcc gataaagctt gccgacatcg gtcacggctc catcgccttg ggcaaggagt
    89881 gcgtcgcggt gcagatgggc aacaacggta acaagatcaa gatgggggtg gagcaacggg
    89941 actcggccat catggccggg gccgagggcg ccaccacgct cgtggtcatc gatggtaagc
    90001 tcatcgtgcc tccggattac gtcatagacg agcacgatcc gaaccttgct aagctgttgc
    90061 acgagaagtt caacctgcgc gagggggacg ccatcatcat cggcaccgcc tccacggtct
    90121 ccaaggccga ggacggtgcc ttggcggccg ccttcgatct actctagtaa cctttcgatc
    90181 tcctttttat cgtccgtctc cgggaggcat cttcccttca tgcatagccg gtatcccgcc
    90241 ggtaacgccg gcagaccttc cagatgctcc gccttgacga tgagaaggtg gggatggtac
    90301 ccaaggaacc gggtatcgga atctccgaac acctccaggg tgcgggactc ctccttcatc
    90361 agcaccccgc acatgaacat ggcgtaggcg gaaggcgtca ggtgcagttc gcgcatgaaa
    90421 tgcctctcca ctccctccaa ggcctccacg gtccgcgggt cgttgaacag cgcggccaat
    90481 tgagctagca cgtagtaggc caccgagttc ccggaggggg aagccccatc atagaggtcc
    90541 ttcatccgaa tgagcaggtg cggatcgtcc cgcgaaaggt agaacccccc atcctcccgg
    90601 tccaggaaca gcaccatcat cccctccacg atgtccatgc tcctctcgag atgttccttc
    90661 ttcaaggtgg cgaagtacat ctcaaggtgc gcccaggcca gacatgcgtg gtcgtccaaa
    90721 agcgagggga cgcccacctc gccctgacga taggtatggt agagggcgcc gtccttcacc
    90781 aattccttct ccaggaggcc gagggcctga gcggccatgt taatggcgtc ctcggatccc
    90841 agcagacgat gtgccttgca taacgccact atcatcagac cgttccaatc ggtcagaacc
    90901 ttgtcatcca gagctggacg cgcacgctta tctcgtttcg aacgcagttc ttcccggacc
    90961 ttctcgtccc aggcgcgcat ctcttcaggt tccatcccct tcagggaagc gaactcctgg
    91021 atggtcttga ggcgatgcag gacgttcact cccgaccggg tgcgggtggc ctcgtcccgg
    91081 aaattacctg attcccagat atcgtaaagt tctctgaacc gcaccaggtc gtccggcgag
    91141 agcgatgcgg ccagctcctc gaacttccag agatagaacg ccccctcggt cccatcggag
    91201 tccgcgtcct ccgaggagaa gaacgctcct tccgcggagg tcaggtcgcg tttgacataa
    91261 cctatcagct cgttcgcagc ctgccgatat tcctcatccc tggtggcggc gaaagcctcg
    91321 gtcaaggcca ttaatatcag cgcctggtcg tacagcatct tctcgaagtg cggcagatgc
    91381 cagcggtggt ccgtggaata tcggtggaaa ccgcccccca gatggtccct tattccgcct
    91441 ctgacgatgt tgtccagggt cttgagcgcc atgtccatgg ccttctggtc cttcctttca
    91501 cggaaaacgc gaagcagaaa gagcaacttg tgaggggacg gaaacttcct ctccccgtcg
    91561 aaaccgccgt atcggggctc gaagtcctcg ctcaagtgct gtagcgtcag ctcgatgagc
    91621 tctgacacat ccccctcggc agggtccctc tcgaaggagt ccagcatctc caagaccttg
    91681 accgccacat ccttgattcc ctcccttcct tcctgccagg cgcgatgcac cgccggaaga
    91741 aggtcgatca tccccgtcat tccctggcgg gaacgcttgg gcagataggt acctgcccag
    91801 aaagggacac gttcgggggt catcaatatg gtcagaggcc agcctccccc accggtcatc
    91861 atctgacaga ccttcatgta caaactatca acatccggcc tctcctcacg gtccaccttg
    91921 acacagatga accagtcgtt catcatcgtc gagacgtcct gatcttcgaa gcattctcgc
    91981 tccatgacgt ggcaccagtg gcaggacgag taacctatgg aaagcaggat cgggcggtca
    92041 agccactcgg cctcctcgaa cgcctccgag ccccatgggt accagtccac aggattgcgc
    92101 gaatgctgca gtagataggg gcttcgctca gtggcgaggc gattggtagg tccggccatg
    92161 aagggtgtta acgaaattac ttggtaatct atctattcct gtcgagtacg atatcgggtg
    92221 aatgtgatag tattatatca cggtcgccca attccctttg ccagtatttc cgcgcttagg
    92281 atgggatgcg ccggtgaaca ttcgcaaatg gttgggtgga gggagggtca gcgctagcgt
    92341 cagcgaaagc aagtcccttc gttacgccac tgttttcatc ctgcttctcg gcgtggtatc
    92401 ccttttcgcc gacatgtcct atgagggtgc gaagagcatc agtggctcct atctgaaaac
    92461 gttgggggcg agcgcggcca ccgtcgcact cgtggccggt ttcggagagt tcatcggtta
    92521 cggttggagg gtggtctccg gtcacgtcgc ggaccgcacc ggccgctatt ggaccatcgt
    92581 tctcgtcgga tacgccatga accttttagc gatcccgcta ctggccttcg ccggcaactg
    92641 gtacatggtg gcgatattga tcgtcctgga gcgaatgggc aaggccataa ggtcgcccgc
    92701 tcgcgatgcg atgatgtcac acgccgccac caagaccgga aggggttggg ccttcggggt
    92761 gcaggaggct ctgtcctccg tgggagccat gatagggccg atatccatat tcctggtgtt
    92821 cctgatgggc gggggatatt ccactgcctt cctcttgatg ggcgtcccgg ctatcttaac
    92881 cttgatcgtg ctttattaca cttacaaaaa atatcccaag ccgcagctga tggaggcggt
    92941 tcagccacaa gagaagacgg tgcttccccg gcgtttctgg ttgtacgctc tggcggccgc
    93001 tttcatggcc gcgggctaca tcgattatcc tctggtggcc tatcacatcc agaatcacga
    93061 actggccgat gagatggtga tacctctgct ctacgccctg gccatgggtg cggacgccat
    93121 ctcggccatg gtattgggca ggctatttga tcggggaggg gcaaaagtgc ttctcttcgt
    93181 cataatccca gccgccttct tcccgctcct ggccttctcg gattcgatga tattgatcgc
    93241 cgccggcatg ggccttttcg gactggggat gggggcgcag gagtccgtaa tgagggcggt
    93301 ggtggctgac ctggcaccgc ccggaaaaag ggcgacggcg tatggttatt ataacaccgt
    93361 gttcggcatg ttctggttca taggctcact gggtctgggc tttctctatg acctatcgat
    93421 accgaccatg atcgcgatct cggtcggatt acagctggta tccgtaccgc tgttcctcat
    93481 gttcctgcgg gataaaacgg tctgagaaag ggtttggaag gggtttgggc ggccaaaaaa
    93541 ggccttaaac cccggtttgc gtttctcctc ctattggccc agcggggtac tttgatccca
    93601 caggacgaaa ttattaggta atgcgcattt aaataaattt tcctgctcgt tatcatagac
    93661 gatcgatgct aaatggattt tcgaaatatc cttatccaat aaaggtatca acaggaacag
    93721 gtgtgaacga tggctctgaa tctacgttgg attggtgcct tgtggggggc tgcggtaggt
    93781 atcatactag ccgatgttct ctacttctta accgattctc tgacctcctt tctgctcttc
    93841 atcccggggg cactgatcgg ttattggctg gctagacggg ctttacgtaa atggggatcg
    93901 gtggaacagt acctcaaagg cggcaaatag gccaacattt ttaatcagac cttacaatat
    93961 acacggcagg agaagggatt cctttgccag acattaggga tagggtggaa gacgaccggg
    94021 gattgctgaa gaagatccaa atggtcgtgc cgggattccg tggctacagg atcagggagg
    94081 acctcaggga ctccgatcgc atgctcaggg tcgaactggc caagaggcta ggcctgcaaa
    94141 ggtcccaact ggaggatgcc agaagggcgt tggtcagaga gaaccccatg tccaaggccc
    94201 tggaggagat gggcggagtg gtcaacacca tgaagagggt ggaaggggag atccttcacg
    94261 ccgaggtcgg ctactcaggt atctccgcgg acatcaagat gaaggatgac gagcttaacc
    94321 ggctgtacga atatgacaac tccatgatcg agagcctcaa cttcattgac gatgcgctca
    94381 tcaaggtgcc gggaatggta aggtccggga acgatgccgg cctgcgggac gccgttgata
    94441 cggttaggac cagggtcgat gggctggaaa gccgcttcaa gcggcgcaag gcggccataa
    94501 ctggaacggg gctgtgatca catgagcttg atcggtgctg agacattcaa ctgggaggac
    94561 gggaacaagc ggaacaacat catgtaccgc atgccccgca acataaagtt caacgataac
    94621 atcgtggtgc gcgaggatga gatagccgtt ttctaccggg acgggaaggc gctcgcctac
    94681 ctggaccgtc cggaccgtta cgctctcacg tccttgaacg cgcctatcat cggcaaggtc
    94741 atcgaggcct tgtccggcgc gaaacagcag gccgagatag tatacctgca gaagagggcg
    94801 ttcgacggca agtacggaag caagcaacct taccaattcc gcgacgcgga gttcggtatg
    94861 gtcaacctgc gcgtcttcgg ggagttccgc tacaaggtgg gcgctccgga gaacttcgtg
    94921 aaccagttcg tgggaacctt caacttcgcg acctcttcgg acgtcgaaga taggatcaag
    94981 gaacagatgg tggtgttgat ctacaacgcc atcggggaga tgaagaacaa gggcatgggc
    95041 gtggccgacc tggcaagcca gctcatgaac atcgagcagg tggtgctggc caaagccaag
    95101 gaccacttcg agctctatgg cgtgataatc gacaaggtct ccgggatgta cgtctccctg
    95161 ccggacgaag tgcagaaggc ggtggacatg agggcctcca tgcagatcct caataccaac
    95221 tacgccacct accaggccgg acaggccatg cgcgaggcgg catccaaccc ctcgggcggg
    95281 gcggcggcgg ccggtgtcgg cgtgggtgcc ggtttcgggg cgggatacat gatggtcgat
    95341 gccatgaggc agggaggggc ggccccggcg gccggtgctc cggccgcggc acccgcggca
    95401 gctcctgccg cagtggctat ggtcgcttgc tccaagtgca gcacccccaa ccccgttgat
    95461 ggcaagttct gccggaactg cggcaacaag atgcagaaca acaccgtgaa gtgctccaag
    95521 tgtggcaacg aggtgccctc ggactccaag ttctgcccgg agtgcgggca gcagctcaag
    95581 ggcagcaaga actgccccaa gtgcaacaag gagtctccga tgaacgccaa gttctgcccg
    95641 gagtgtggca ctagcttcta gggtgttcat atggccagca tgaactgcac caaatgcggg
    95701 gctccagtgg agttcgatgt gggcgacaag ttcgtcaaat gctcctactg ctcctcacag
    95761 atattcatcg accgctccgg ggcagggttc tattacgcct tgccgttctc ggtgcaggag
    95821 aacgacgcgg tcggcacctt ccggcgctgg gccggaggtt ccacccgagc caaggacctg
    95881 gacaagctgg cccagattgc atcgctaaag aaacagtact ttcccgttta catgttcaag
    95941 cgggacgtca gcgggatgga acatatatac atcgaaccgg ccgcctccac gacgttgcca
    96001 ggattacata atctgaaggt tccgggcggt gacctgaagg tgttcgatga gaggttcgac
    96061 accagcgggg cggagctgat caagatcgat atcgagatgg ctccttactt gagctctcta
    96121 cccggcgcgg ctaaggagca ggcgctagtc tacttcccga tctggcgtct ggattacgtg
    96181 ttcgagcaga agaactacgt ggtcatcatc agcgcttcct cgggagaggt gttctccggt
    96241 gagttcccac cgcgcagctc cggggcctac atggccgtgg ccggaattgg cttcgtggcc
    96301 ttcctggccg aagggcttct agcgcttttc gtgccgctgt tggcaatagg tctcatggcg
    96361 gtcaccgtgg tcggagtgtt tgccgcctcc aacttcgtag ccaggaggat gtgatatgtc
    96421 cataagcgtt ggtctgaact gcccggcctg cggtggggcg atctccataa gcgaagggga
    96481 gaacgttctc aattgcaatt attgcggttc cttgctgtgg gccgagggcg acgcgggagt
    96541 gatgacggtt gccttccgga acgttcaggg aagggattcc gtcctgcggg cgaccgagga
    96601 atggtggcgt aaaggcctga aggcccggga cctcaagacc aagggcaagc tcctggagtg
    96661 ctatcccata tacctgccgt tctggagcac caccacgcgc atcgccggct ggatatgcgg
    96721 ttacgaggag agacgctata ccgaccgcga cgggcatacc cgtacagaac ggataccgaa
    96781 ggaggagatg gtccttcacg attatcgtta caccaacatc gcctgcgacc cgggcgacct
    96841 gggtatcaag tacctccgaa atgtgaacgg ggaagcgtcc ttcgccgatt tcgagagcat
    96901 tcccacgttc gaaagtacca ccagcaagga tgacatggtg gagatgtcca agcagaacgc
    96961 tcttaacgat gccaggagcg atgctaacgt cccgcacatc accttcgaga aggtcaccgc
    97021 gataccgaag cacataagcc agatattcta tccggtatgg gtggtccgtt acgcttacgg
    97081 cgagaggatg tacatggcca ccgtggacgg ggtcaccgga aaagtactat cgggacgggc
    97141 tcccggagac gcgctgtatc agagtctggc catgaccggc ggtacgtccg tgggagggtt
    97201 ggtggccgca ggcggactgg ccatcggact gggcatgggg gagggggctg tggccataat
    97261 cggcctggtg gtcggagtgg tcatactcgg cttcacctat cgcttcttcc ggcatggctc
    97321 ggagataacc gaaggggact tcgacgacaa gaggtccacc aatctccgga aggagttgaa
    97381 gaaagggctc aacatagatc tgggagggtt ccggatatga aggtcgttca ggtcaaatgt
    97441 ccccgttgcc agcagcccat ctattccaag gtcaaggacc gggccttcta ttgcgggcat
    97501 tgccgcacca tgcatattcg gaacggtgga ccgagcatca tcgattttga cataggcgag
    97561 ttcaacgtca acgccccgcc ggaccgcatc tacatgccct tctggaggct gttctccacc
    97621 ttctcgataa acgaatcgaa ggtgtccgga ggcacgatac acaagctggg ccgaatgata
    97681 aagggggacg ccaagggagg caacctcttc atctacgtgc cgggctggga gacggacgtc
    97741 ggcaccttca agcaatggtc gatgggtctc actgagaatc agcccgtgta ttcgttacga
    97801 ccggacttca acaacgtgga gagaggcgcc acgtccgtat ccaaggagga ggccatgcag
    97861 atggccgatt tcatcatcgt gaccatggag gcggagcggc caggtgtcct gcagtatctc
    97921 gactacggat tgcaggtcca tgacgcccgt ttggtgtatc tgccgttcgt ccgtggaccg
    97981 tcggggctgg cacccggctt ctgagcatac aaagattgaa taacagttta cggatattat
    98041 ccgtacatgg ccgagcttcg ccttagcaag gggatgatcg ccgctatcgt cgcggtcgta
    98101 gcggtagtca tagtgttgat gatggtcgca ctgtcataca atggcatgat ttccaagcag
    98161 caaggtgtgg agaacgcctg gggcaacata gaagcccgct accaaaggcg agtagagctt
    98221 atcccacagc tacaatcggc catgaacctg tctatcgagt tccaagctag cctgtatacg
    98281 aacattactg aggctcgaac cagatggcta tcctcaattg gtaacatacc agctcaattg
    98341 aacgcgaccg aggtcatgga cagaaacctg gccgtgctcg tggcgaccta tgagaactat
    98401 ccccagctag acctgggcgt catacagtcc ttcgtggcgg aactatcctc cacccagggt
    98461 atgatcgatg cggcaaggat attctataac gacgcggtaa gggagtataa cacggcgatc
    98521 aagaagttcc ccaacatgat gttcgccgga gccttcggtt tcgaagaggc ggtctactac
    98581 tcacagggga tgtgaatcgg taaatgcgca tttcgcgccc tatagcgatc acgatcgtga
    98641 cgttgatcgt ggtatccatg ctcatactgg cgggattcgc tatatggaaa tattttcagc
    98701 ccgatcctcg tttcgagggc attcctgagc tggactacta cgtcaccgac gaggtcggcg
    98761 tcctctataa ttactatgag atcgaagaca tctgctacac ggtcgatatg aacacatcct
    98821 gcgagatcgc cgttctgatc gtgaacagca ctctgccgag aagcgccaac gagttcgctc
    98881 tccgtacatt ccagatgaac gagatcggta aggaaggaaa ggacaatggt gtgctcatcc
    98941 tcatcgtcac cagcactcgg gaatggaagg tagaggtcgg ttacggtctg gaaggggtca
    99001 tcacccctac gttcctgaac cagatagcta cggattatgt catcccgtac ttggaggttg
    99061 atgattatgg cgaaggagcc tacaacatgg ccctcttcat cggtgctgag atattggaca
    99121 aatatgaagg ggccgaatca ggggatccgg cattcccgat ccacggcatc cccttgacga
    99181 tcacgcaatg gataattata atcgtcatcc tggtcgccct tactgcagtg acaaggggga
    99241 ggatctggta cctgctcttc ttcattctga cctttggtcg cgggggaggg ggtttcggcg
    99301 ggggacgctc gggaggaggc ggtgggggtg gaagattctg aacctcaaca gcaaacccca
    99361 ggaatatttt cctcctttca acaaccttta actaatctct atttaatcag ccaaaaagtc
    99421 aggtgcgaca gatgtcctta aggtccagcg agattgagac gaagtggcag gaacgttggt
    99481 acgcctcgcg catcaacgag gtcgagaagg acggccggcc caagttcatg ttgatcttcg
    99541 cttaccctgg cgtcaccgga tatctgcatg tcgggcacat gcgcggcttc acctacgtgg
    99601 acgccatcgc ccgcttcaag cggctggaag gctacaacgt gatgttcccg gtggggacgc
    99661 acgccaccgg caacggggcc ataagtctgg ccgcccggat cgcccgaaag gaccagaaga
    99721 ccattgacta cctttgcggc aacacctgtc cgatcaacat cctcgactcg ctgaaggacc
    99781 ccgtgaaggt ggtggagttc ttcaacgagg tctacgtgaa caagtactgg aagcgtttcg
    99841 gcttcatgtg tgactggagg cgcttcacct ccacggtcag gccggattac cagaggttca
    99901 tccaatggca gttccgcaag ctgatgcaga aaggactgct gatccagaag ccctattacg
    99961 ctcccgcctg cgtggcgcac ggtccggtgg ccatagacgc ttccgagacg gacatccaat
   100021 gcggcggttc tgcggaaacg gtagagtata cgcttctcaa gttcaaatgc ggcgacatgt
   100081 tcctgatggc cgccaccctg cgtccggaga ccgtgttcgg tcagaccaac ttctgggtga
   100141 acccgaacgc ggattatgtc aagatcaagg tgaacgacga aacgtgggtg gtcagcgagg
   100201 acgcctactt caagctcacc taccagatgg agaacgttga gcgggtggca tctatcaaag
   100261 ggtccgaact gatcggcctg aagtgcctcg ccccgatggt gcaccgggag atactgacgc
   100321 tgccggccga cttcgtggac cccaacgtgg gaaccggtct ggtcacctcc gttccttctg
   100381 attcaccgga cgactggata tcattacgtg cgatacagca ggatgaagcc acccttgacc
   100441 gctatggtct ggacaaggac gccgtgcgag cgatcagacc catcgccatc atcgagatga
   100501 agggctggtc ggaccttccg gccgtcgagg tgacggagag aatgggcata accgctccgg
   100561 gcgatccaaa gctggaggac gccaagaagc tggtctacaa ggacggtttc cacaccggca
   100621 agatgaacgc caccgccggc gagttcgccg ggcttccggt aatggaggcc aaggagcgca
   100681 tgaagcagct catgctgacc tccggagagg ccgcggtgat gtacgacctt tccgagctgg
   100741 tgacctgccg ttgcggcgag cgggtggtga tcaagaaggt caccgaccag tggttcatcg
   100801 attacgccaa cccggaagcg accgccgcct ccaaggagca cgccaagagc atggacatat
   100861 tcccggcgga gtactatcag aacatacatg gcgttctgga ttggttccgg gaacgcgcct
   100921 gcgtgaggca aggcaactgg ataggtacca agttcccgtt cgacgagaag tggataatcg
   100981 aggccatatc cgattcgacg ctatacccga tctactatac catttccaag ttcgccaacg
   101041 acggttcgat caaggccgaa cagatgagcg aggagttctt cgacctggtc attctggaca
   101101 agggcgatat ggccacggtc tccgcctcga ccggtatcgc acaggaggtc ctcaaaaaga
   101161 tccgtgacga tgttcactat tggtaccccc tggacctcaa cctgggaggc aaggagcacc
   101221 tgaccgttca cttcccggcc ttcctgatga accacgtggc gctccttccg aaggagatgt
   101281 ggcctcgcgg aatattcgtc aactggtggg tgatgggaaa aggtgggaag atatccaagt
   101341 ccaagggcgg cgcccagccg atcccgggag cggcggagga gtacggcgtg gacgccctgc
   101401 gcctctacta cgcgcacatc gcctcgcccc acgccgacgt ggactgggac aacgaggccg
   101461 tggaaggcta caccagtcgc acggagaaga tggaacgaac gctcctggac ctcatgtccc
   101521 tggacggcag ggagagcgat gtggatggct ggatgatctc ccgcatggcc tcccgtgtcc
   101581 ttcgggtgaa ggagatgatg cgaacgtacg atctgcgttc catggccaac gaggtctatt
   101641 tcgaggcgtt caacgacctg cgctggtacc agaggagggg aggttgccac gctcccacga
   101701 tcaagcgcgt cctggacctc ctgctgccgc tcatgatgcc catcacaccc cacaccgccg
   101761 aggagctgtg ggaggcggcc gggaataagg aaatggtgtc cgccacgctg cttcctgaag
   101821 taagggaggg ggagatcgat gtatcgaagg aaagggccga ggattatctg cgcagcctga
   101881 tggacgacgc caacgagatc ctcaaggtca ccgggatgaa gcagaccaag atcaccttct
   101941 tcaccaccgc cccctggaag cgcgaggtgg tctccatggc catggcgctg caggagaagg
   102001 gcgatctgaa ggtaccgacg ctcaccaaga tggccatgtc cgacgagacg gttcgttcga
   102061 aaggaaagga ggcttccgat ttcgcccgga agaccgccga ggacctcatg aagaggtcgc
   102121 ccgccgaagt gaggaaactg gcgcagcggt tcgacgagat atcgttcctc aaggccagca
   102181 gggagttcct ggagaaggag tacggatgcg cgatagaggt gcacgaggcc ggcgagcatg
   102241 atgtcgcgga ccctcagaac aaggccaggc aggccgctcc ctggcgcccg gcgatattgg
   102301 tcgagtgatc agtcgcccca gcgcttgaag agctcgtgcg gctgccctag ctggtccagt
   102361 atcttgccga ccaggaagtt caccaggtcc tccaccgtct gcggtctggg atagaatccc
   102421 ggacttgccg gcatgatcac cgccccgtcc tccgccagtc gaagcgcgtt cctgagcatt
   102481 atggggctct gtggggtctc ccgggggacg attatcagct ttcgccgctc cttcatgcac
   102541 accgcggccg ccctggtgac cagattatcg gcgataccgg aagcgatctt ggcaagcgtg
   102601 gactcggaac aaggacagac gatcatggca tcgaagcggt gactgccgga ggcgaccggg
   102661 gcgaaaagct cgtcctcgtg atacacctcg tccgcaagct gcagc
//
LOCUS       DAOPZI010000003        58737 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_391_length_58737_cov_10.885587, whole genome shotgun sequence.
ACCESSION   DAOPZI010000003 DAOPZI010000000
VERSION     DAOPZI010000003.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 58737)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 58737)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58737
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_391_length_58737_cov_10.885587"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..860)
                     /locus_tag="PKM11_01545"
     CDS             complement(<1..860)
                     /locus_tag="PKM11_01545"
                     /inference="COORDINATES: protein motif:HMM:NF013752.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - transposition, DNA-mediated
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HNX47228.1"
                     /translation="MVATVVEITSEIFKFDGQSRLDTFSIDLGRCSEVEAHRLQLAME
                     GIRKNVDSFPFWQRRKRVGRPSSNERTIMIGFLIQQLFRTTFRDAEGLLNMLSWYFQI
                     ERVPDHSVLCRAMSSQRWTSLLERFFSFVIGNLPKRNVIVATDATGYSGRKRGWRETP
                     YAHRPNEDWVKTHAAIEVDRFLILSYELTASNVHDSQVFSDVWMKLPENIVPVRSLAD
                     SAYHGEACLAAARLHGATPLHKIKKNAKGLMEHRVNYNKLVFFAKQFPQRFAALTAKR
                     NHAETVFSMIG"
     gene            1068..1844
                     /gene="heR"
                     /locus_tag="PKM11_01550"
     CDS             1068..1844
                     /gene="heR"
                     /locus_tag="PKM11_01550"
                     /inference="COORDINATES: protein motif:HMM:NF037099.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heliorhodopsin HeR"
                     /protein_id="HNX47229.1"
                     /translation="MEDAGSDEIKFKKLRRFNLIMGFFHFIQAAIMLAIANYDVQMRF
                     TTSYIDAGMGFPPTGPGSAELLFSVPLGPMVAIFLLMSAIAHFSVSTFGYGWYVKNLK
                     MNMNKARWFEYAVSSSFMLVVIAWLCGMFDFISIMLLFSLNACMNLFGYMMEAHNQNT
                     KKTEWTSFIFGCFAGLIPWIALFMYFTGVRGGSPPDFVYGIMISIAFFFNVFAINMIL
                     QYKKVGKWKDYLYGERVYIILSLVAKTALAWQVFSGTMVA"
     gene            complement(1875..3374)
                     /locus_tag="PKM11_01555"
     CDS             complement(1875..3374)
                     /locus_tag="PKM11_01555"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47230.1"
                     /translation="MMERHYFVAKMPDEPGALHRAAEIVKRHGGNIDRIQYDKRIDPY
                     TVFFEARCSEDEYQAMRSELQAIGYLQGKMVVPSFLKFDVVLPNSSGALFDFLNHTTA
                     AKCNIDFLDFDDRGKHPERLTVSLTVEEAGAVDRLLEKLKSIYPLEILEYDTTGQHLD
                     DTVFYIRFAQELRALVGEAEDAFLLRLLSDINHVAQELMNLGSDPKQAFSDVLRSGRG
                     LRETSGDGFYADLQEVCLGKVDLLCVQLPCGGNCYLLRNGSEVSMVDTGFGIYFRDLD
                     KLMEREGWGGVGLVRNVLITHGDADHSGSAGLVDATVRMHPDTLEMIRRSDRAYGSES
                     EGSVLAEVYTKLINLFSRFSVAEHPDVYPMKATGKRGDFPVLATLDLAGMRCEVLEGF
                     GGHTTGQVFYFLPEELVLFTGDSLINFESLTEERRDFATLAKNLMTSVNVDSVKASKE
                     RKALLRLMEMEESKRSDGRKCLVCGGHGAVSVLCEGKLVQHTPVRRYVT"
     gene            complement(3443..3676)
                     /locus_tag="PKM11_01560"
     CDS             complement(3443..3676)
                     /locus_tag="PKM11_01560"
                     /inference="COORDINATES: protein motif:HMM:NF023159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HNX47231.1"
                     /translation="MEQDDRESALKELRTIPIVGEKVAEPLYMLGIRSVKELIGRSPE
                     DMYGELRTMKGYYVEPCILNQLKVAVSMAAKMK"
     gene            complement(3722..4327)
                     /locus_tag="PKM11_01565"
     CDS             complement(3722..4327)
                     /locus_tag="PKM11_01565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47232.1"
                     /translation="MGDVPLRIAVLVASYAFLGGAIKYIDQAYDESIGSIRIAKLLAV
                     LSGLVMGGVMVVDGGFSTAFFLAMLISLVVTKKIDNFSFLIGTLVGLMTFLIGGFIWG
                     MDVMLLPLVVFLIAGAVDELADGFAHGRDLGRAVEYFLHYRPFSDFALVILIIVVPFD
                     WIYLAPYFAFTFSYLLIGMLDEGQVTQSVRVIIRKASQLRP"
     gene            4850..5590
                     /locus_tag="PKM11_01570"
     CDS             4850..5590
                     /locus_tag="PKM11_01570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47233.1"
                     /translation="MKWRSHVSIGKAIADVLELPPGERKAFLDGIVEPDRHKERVSGP
                     GYSYRVSHHHPRRRVFMLHVWMARRSFLRNNSYQGYRHLGMALHYLQDKSTSKGFMGL
                     SHDRREEALAEVKVPMEAIERGFNKYLSNPEFVSRSLELTKPLKDVDQIMAQASFRSA
                     AVAAAVTDLRRPSGLERKLRSLHRRRLLLHLPLSIGALAVGSSLSLAWWNAIPFAMAI
                     AISLIVLVMDRPYRQLSRVALWHGLKSH"
     gene            5699..6973
                     /locus_tag="PKM11_01575"
     CDS             5699..6973
                     /locus_tag="PKM11_01575"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: protein motif:HMM:NF013071.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HNX47234.1"
                     /translation="MSRDQRLEDNWALYHAWARAKSEGRSLGVLFCLAPDFLAAGPRH
                     YRFMLKGLAETMDAAERAGIPFFLLEGDPSVEVPRFLREWNVSLTVTDFDPLRQKSEW
                     RAATMEGCDSGFEEVDAHNIVPCWIASPKQEFAAATFRPKIKRHLPDRLEHLSPSPSK
                     FGEWPGDAGTKYIKKIIARYKEVADDRWEGGPVQARRALSEFLRDRLPGYAERRNDPN
                     LDWVSQLSPYLHFGMISAHRVALAVMAATAPQPDKDAFLEELIVRRELSDNFCLYNRK
                     YDSTEGFPAWARATLRDHLADEREYVYAEEELGKANTHDPLWNAAQVQMATEGKMHGW
                     LRMYWAKKVLEWTETPAEALRIVNAFNDRYEMDGRDPNGYVGAAWSIGGVHDRAWTER
                     KIFGKVRYMNLNGAYRKFDVDAFVERYVNPDR"
     gene            complement(6957..8468)
                     /locus_tag="PKM11_01580"
     CDS             complement(6957..8468)
                     /locus_tag="PKM11_01580"
                     /inference="COORDINATES: protein motif:HMM:NF024118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47235.1"
                     /translation="MRITVHGGAGVVGGNKIHVDLGDRGAFLDFGEPFDIGNLYCSEF
                     VRPRTGRGLRDYVKLGMLPLLDCYRPDLYPVDLPLTDMAPARVDALFLSHAHFDHYGN
                     AGFLRHDIPIVSSPMTYAILRASSEIGRTGMSTELFDHVVRSRKEMEPRILVSTRTKD
                     KEVQGRHWVLTGEPVDEAPEWKKGGSCQVASGCGELNGIEYLSFPVDHSIYGATAYAL
                     RRNEGEWIVYSGDLRMHGAHGQDTVRFAEEAGSLQPKALIIEGTRIGRPAPEREMTER
                     MVHDNCLAAVENGRGLTIADFSANNFERLDTFIDIARRTGKRMVVTHKDVALLQSISK
                     VDGNVRKDSLWVYRSLSDKEVDIVDDLQKEGWQVADPDDIAKGPKEHMLCLSFWDMTK
                     MLDLDWNGGTYVYSNSMAYDLRQTDNLQKLMNWIELMGFDCRGISKIDGNLDFEEGFH
                     SSGHLAVADLWNVVKKISPELVVPVHCAHPEMFAEQCPVRTLLPEKGKVIDLG"
     gene            8574..9833
                     /locus_tag="PKM11_01585"
     CDS             8574..9833
                     /locus_tag="PKM11_01585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HNX47236.1"
                     /translation="MAAMTFAQKVLSKASGKEAHPGDIVSAKIDLAMSHENAALVLRS
                     FKEIGAKEVWDPEKIVLLFDHRIPANTTKAAEGHQSVRKFVTAEGLPNFYDMREGICH
                     QVLPEKGHVLPGMLIVGTDSHTTTYGAFGAFSTGIGATEMAAVWATGELWMKVPQTFR
                     FNLNGKLDDQVAAKDVILHLIGKMGADGCDYRCVEFAGPVVNHMSVSGRMTMCNMSME
                     MGAKAGVTFPDEKTRDYLKGRTSKELVPVTSDKEAEVEKIFDMDLTGLSPQVAYPHSV
                     DNVKPVEEMAGIPVDQAVIGSCTNGRAEDLLAAERILHGRHIPNSVRLIVVPASREVY
                     LWAADSGILASLVRSGAIVTNPGCGPCLGAHQGLLAPGERCIATTNRNFRGRMGSPES
                     EVYLASPATVAASALKGQIADPREVRV"
     gene            9830..10312
                     /locus_tag="PKM11_01590"
     CDS             9830..10312
                     /locus_tag="PKM11_01590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HNX47237.1"
                     /translation="MKGKVWRYGDHVNTDVIIPGRYLDDYDLKNMAKHAMEDLDPKFA
                     KDVTYGDIIVAGRNFGCGSSREQAPLALKHAGVGAVVATSFARIFYRNAINIGLPVIE
                     FDATGMFEKGDVALINMEKGIVVNETSGRTSKFEPLPPFLLEILKEGGLVPHSAKRFR
                     "
     gene            10472..10645
                     /locus_tag="PKM11_01595"
     CDS             10472..10645
                     /locus_tag="PKM11_01595"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit K"
                     /protein_id="HNX47238.1"
                     /translation="MKYTRFEKARIIGARALQISLGAPVLLEIPEGMIDPINISQLEF
                     DKGVIPITVKRDI"
     gene            10656..11267
                     /gene="rpsB"
                     /locus_tag="PKM11_01600"
     CDS             10656..11267
                     /gene="rpsB"
                     /locus_tag="PKM11_01600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HNX47239.1"
                     /translation="MSDESKTELLVPEDVYLTSGVHIGTQQKSADMKDFIFKVRTDGL
                     YVMDVKQTDVRIRAAAKFLSRFKTDRILVVSARQYGQKPVRIMSKAIGAMYFEERLIP
                     GSLTNPVLNRFIEPDVIVVTDPAADQQAVAEALNVGIPIVALCDANNETRNVDLVIPT
                     NNKGRRSLACVYWLLTREILKEQGKLTRDEDFKLGIDDFEASL"
     gene            11307..12125
                     /gene="amrB"
                     /locus_tag="PKM11_01605"
     CDS             11307..12125
                     /gene="amrB"
                     /locus_tag="PKM11_01605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AmmeMemoRadiSam system protein B"
                     /protein_id="HNX47240.1"
                     /translation="MVRRAAVAGQFYSSSRSALIKELEQCFLSPLGPGELPEVVKDGP
                     RNIVGAVVPHAGLVFSGPVAAHVYAEMAADGMPETVVIIGPNHTGHGKAVSVSSEDFE
                     TPLGIVRSDRDIVSRLKGVVEIDRAAHLYEHSLEVQLPFLQYLDPEVKVVPIVMGRQD
                     LIMARETAKVLGEACAGKDVVILASSDLSHYLPAGVARKRDEMVLERILRLDAEGLID
                     VVERNDISMCGSGPVASMIMACKGGKARLLHYGNSGDVRPMDEVVGYAAAVVVK"
     gene            12209..13174
                     /locus_tag="PKM11_01610"
     CDS             12209..13174
                     /locus_tag="PKM11_01610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47241.1"
                     /translation="MDGTKTCPYCGKLANADSQFCQGCGRSISSPPQYSEQPPQQYQQ
                     SQNYQQPPQQYDQPPQRGGWQEPAPAYGAPAYGAPAPPYGQSYGGAKGQIAGAIQNRG
                     VTDEIMSGIWVFWPILTIVLGVIIMVALTIFIGWAGLIIGLVIALVMYCVLNFKLLKR
                     MDEHRKREMALRMAIIAFLKEKGAETQRAQLIVNEISALESINQEAMYKEKERTPLLW
                     TILGVLPILNLIVMYFLAEFPFDHDKRWHAFTQYTQAACQKLGINIMTPSWSTIKERP
                     NVLFLILTLLFSIVVFVWYYFIIKDLNEHFQAQWQFEDQLMAQLR"
     gene            13309..13869
                     /locus_tag="PKM11_01615"
     CDS             13309..13869
                     /locus_tag="PKM11_01615"
                     /inference="COORDINATES: protein motif:HMM:NF024183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47242.1"
                     /translation="MKYCGSCGNQVDVRAEICPKCGIRVSQEGGARGGATIFCQHCGN
                     QMDVRAEVCPKCGIRAAQTQPQYQQQPQPQYQPQPQPQYQPQPQYPPQYPPPYQPPVA
                     QKSEGLAAVLSFLIPGLGQMYNGEIGKGILFLILAFVFAALMIVLIGFILYPILWLYG
                     IYDAYNTAKKINQRNAYPGQQYQRGY"
     gene            complement(13916..14797)
                     /locus_tag="PKM11_01620"
     CDS             complement(13916..14797)
                     /locus_tag="PKM11_01620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HNX47243.1"
                     /translation="MSREVAWRVFAAEFNSSSLEMKGEGEKTPSYLISPLGAKINRIF
                     VVGVLTDNDNVGNENEPVWRAKITDPTGTFYMTAGQYQPEAAMALAKLQPPCFVAVVG
                     KFRTYSPEEGKMYVSIRPERVGKVEASVRDGWVLETCKATMDRISAMEEAMKLVEPTV
                     EKLMQIGFSRPLAEGTVHSLRHYQQEDLTRYKGMTSDALKFLLPEYHTGPDVHLDSAA
                     PEEIDLEEEQDDVDKEALVLSMIESLDSGKGAAWDEVVQKGKSQGIEREEMDSIANSL
                     LDKGFVYEPVLGKMRKI"
     gene            complement(14797..16119)
                     /locus_tag="PKM11_01625"
     CDS             complement(14797..16119)
                     /locus_tag="PKM11_01625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47244.1"
                     /translation="MDREELAPHVEELARVLGEKADKNKIAEELEKYVNLYRVTLEWA
                     KRDILKKMGGNPDAFNDGSGRKSVAELTGDEQSVDLLVKVLTVNPKTIEVGGAHKSIA
                     YGYMADESGRVQYTVWETESVQLKQGSTVLIRNAYTKEYKGTPQLNLGNRASVEESEE
                     ILDVADMPSGGGSAEVKIADLADGMNYVVISGKVSRPEKREITASGEKKTIVTGVLSD
                     DTGSAEITVWKDAELKDGDEVRIVGAYVKSWKGMPKLNLGDKAEIQMLSKGTLGDLSS
                     SVPKVRTLEDVELSGGAMDVVVRGTLVDVREGSGLVMRCPDCRRVLQKSTCRVHGKVK
                     GTDDLRIKSILDDGTSSMSVVFGKELTEQLLNISIEEAVKITTEERNPEAVKEMAEEK
                     LFARTLEVRGMVRSDDFGPMLIARDARFLEVDVREEGAKLLTDMEGFN"
     gene            complement(16272..16895)
                     /locus_tag="PKM11_01630"
     CDS             complement(16272..16895)
                     /locus_tag="PKM11_01630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47245.1"
                     /translation="MVAEKKVGKAKDEDWFAKLDAELSARTDAISKDKEEINFQKTTI
                     NRAIIGDFWNVLNRFSRINVQLNMEPTYSEFAQFEEFPLKWRFKNEYDFEAVNRVQLV
                     DRTQTQGRMGDSLKVMYYAVDSTPYMRMVFDYCEGEHYYKYAGWKRIFGQFVVFDSPL
                     SKFDMDRFHEKLADVVLAWYESHLRNNRDILISHLKEKYERGETFTE"
     gene            17025..17546
                     /locus_tag="PKM11_01635"
     CDS             17025..17546
                     /locus_tag="PKM11_01635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47246.1"
                     /translation="MDVAGGLTSFLEQVQGDPLVYSVLFFIYIIAATLFLPIPVELML
                     FLSPATPFLLKAILLGVGKAVGSMIVFYIGMNVEGPINTLTRKWGFFRMVVNFSKWLV
                     DKLGYLGLYIILSIPIMVDTVPVYLFSIFRKDRCDRDLRLFALTNLAAGMTRAAIVYF
                     AVTELGLGYLFGI"
     gene            17581..18651
                     /locus_tag="PKM11_01640"
     CDS             17581..18651
                     /locus_tag="PKM11_01640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--phosphoribosylaminoimidazolecarboxamide
                     ligase"
                     /protein_id="HNX47247.1"
                     /translation="MVPKNKILKILDEYDKKKLTVATLCSHSSLQIFNGAKKEGFRTL
                     GLTVKDNFRYYDAFPLGRPDEFMKLDSYADLLDNVDELLARNIIVVPHGSFVEYMGTE
                     KFEKMPVPTFGNRNVLRWESHRDKMREWLETAGIVMPRVIDDPKTIDRPVLVKYNGAK
                     GGRGFFIAKDYNEFKMGLDLDQDYTIQEYILGTRYYLHYFFSPIKKDGFRVGDGSLEL
                     MSMDRRDESNIDELYKLGASEELKKLGLFPSFVVTGNVPVVIRESLLPKVFDMGEQVV
                     KRSYELFGGMIGPFCLEGIVTDKLEFKVFEISSRIVAGSNPFISGSPYSDLTEENMST
                     GRRISREIKNAVLTDSMDQVIS"
     gene            complement(18703..19611)
                     /gene="pdxS"
                     /locus_tag="PKM11_01645"
     CDS             complement(18703..19611)
                     /gene="pdxS"
                     /locus_tag="PKM11_01645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HNX47248.1"
                     /translation="MAFTLDLSGLRHGTELVKRGFAKMQQGGVVMDVTNAEQARIAEE
                     AGAVAVMALERVPADIRAQGGVARMADPVKVLEIMDAVTIPVMAKCRIGHFVEAQVLE
                     TLGVDMIDESEVLTPADPFMHVVKKGFTVPFVCGAKDLGEALRRIDEGAAMVRTKGEP
                     GTGNIIEAVRHQRIIMGKVRELKGKDDAELAVIARQIEAPFYLVKEVAVMQRLPVINF
                     AAGGIATPADAALMMQLGSDGVFVGSGIFKSNDPAIRAKAIVEAVTHFDDPKVIAEVS
                     RGLGEAMHGIEISTLAKEQRMQERGW"
     gene            19733..20887
                     /locus_tag="PKM11_01650"
     CDS             19733..20887
                     /locus_tag="PKM11_01650"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HNX47249.1"
                     /translation="MFANRMENVLESGTVKIANLVSKLKEEGADIISFSMGEPDFHTP
                     DNIKEACVRALANDFTYYTPSAGIPELRKAIAERCRTLNNIPCEASNVLVTPTKQAIF
                     MTMLAMVDDGDEVIVPDISWGTFEACAHLAGGKVRHCKISADQGFRMTPESVAERITK
                     RTKLLVLNSPSNPCGAVLTKDDVKGIADLAKDHDFYVLADEIYNQLVFEGEHTSISSL
                     DGMFERTITVDGFSKTYAMTGWRAGWAVAPKNIFKELNKLQTQSITCVTSFVQQACLE
                     ALRGPQDSVALMKKEFKARRDLVHSLIQDIPSLNCPMPSGAFYIMPSYDFDMKSEDMA
                     AYLLNEAHVAVTPGSAFGPAGEGRFRLSYAASRENIREGMSRVKTALAKL"
     gene            complement(20888..21064)
                     /locus_tag="PKM11_01655"
     CDS             complement(20888..21064)
                     /locus_tag="PKM11_01655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methytransferase partner Trm112"
                     /protein_id="HNX47250.1"
                     /translation="MKKDLVDILACPVCKHHPLELQVERADADEIVEGRLLCTRCDVA
                     YVIEDGIPNLLPPE"
     gene            21163..22197
                     /locus_tag="PKM11_01660"
     CDS             21163..22197
                     /locus_tag="PKM11_01660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntG family PLP-dependent aldolase"
                     /protein_id="HNX47251.1"
                     /translation="MRRIDLRSDTFTLPSKEMLDSIPSADLGDDVEGEDPTVNQLQDL
                     AASMFGTEAALLVSSGTMGNLVSLMAHCRRGDEIILESEAHIYYYELGGMSAIVGAIP
                     RLVQGTRGKFTAEQLEAAIRHPDLHYPNTRLVCIENTHNRGGGIVWTPKEVEAVAKVA
                     HDHGLKMHCDGARIFNAAVALDVDVKEYMKHLDSLSFCLSKGLACPVGSIVVGNKEFM
                     EEVRRNRKMVGGGMRQAGIIAAPGLIGLQKMVGRLKEDHRNARRLAEGLNEIPGIKVD
                     MEAVQTNIVLADITGTGWDVDYFVNRACKIGVQVFEFGATKARFVTHYGIDEQDVDDA
                     LARLRRLLER"
     gene            22326..23390
                     /locus_tag="PKM11_01665"
     CDS             22326..23390
                     /locus_tag="PKM11_01665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HNX47252.1"
                     /translation="MSRRLFTVGPVEVFPDTLSSMNRGMMVHRGKDYQDLQHGVVEKI
                     RKVLDIDSEIYLAPASASGFLEGCVRSAVDTKMAGLSNGSFGDRWQLIGQENGKQVQK
                     INGEWGKALRATHLAGKLEKDVEAVTFVSNESSTGVLNPTGEIVDEIRKQGDALIMVD
                     GVTSVGAVDLKLRKLDLDALVFGSQKALALPPGLAVVCVSSRLMEKAAKVKNRGYYLD
                     LIQYKKLADKDLPLTTPPVSLMYGLDYQLDKMLKEGVAKRYERHQRMADMVRGWAMEH
                     LGLYAEDGFRSNTISVIKLNGLDFKEFDKRLRQKGFEVSPGYGNVKDETFRIGHMGDL
                     TEKDIQDLLDVMDETMEEMK"
     gene            23387..24994
                     /gene="serA"
                     /locus_tag="PKM11_01670"
     CDS             23387..24994
                     /gene="serA"
                     /locus_tag="PKM11_01670"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: protein motif:HMM:TIGR01327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004617 - phosphoglycerate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HNX47253.1"
                     /translation="MKLLVTDELSQEGLEMLTKGSGVQVDVKPKIPHEELLKIIGEYD
                     ALIVRSGTKVTAEVIEAGKKLRVVGRAGVGVDNVDVEAATRRGVLVMNTPAANIISAA
                     EHTMAMMLTLARNIPRADASVKSGKWERSKFTGVELMGKTLGIVGIGRVGGEVAKRAK
                     SFQMKLVGYDPYISQELAVKLGVRILPLDKVLEEADFITIHTPLTPTTHHLLGKEQLA
                     MLKPSALIVNCARGGIIDEDALYEALKAKTIAGAALDVFEEEPPKGSKLLTLDNLVAT
                     PHLGASTKEAQEKVSIEMAEHVKMFLVDNKITNAVNVPISRVDPKVSPFIGLAERLGA
                     FCVQLSDGPVKKIEVECHGEIANLDTRMVTISAIVGVLSIVVGESTNIINATSIAREK
                     GIQIVETKVDESSHYTNMLVLRISSDGHKAEVRGTVFPSDLSRIIGVDEFDLDMPLEG
                     DFLLTKHHDMPGMIGKIGTILGKRDINIARMGVGRADKGGDALMLISVDQEVGKAVVA
                     EFRALPNFHEARSIVLSHMRTREYMNI"
     gene            complement(25014..25319)
                     /locus_tag="PKM11_01675"
     CDS             complement(25014..25319)
                     /locus_tag="PKM11_01675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HNX47254.1"
                     /translation="MSSLIAEFSIVPIGAGVSLSPFVAECLRIVEASGLKHQLTPMGT
                     VLEGDAEKVMATIMACHSRVLSMSDRVVTNIKIDDRRDRPADMERKVRSVEEKIRKG"
     gene            25656..26066
                     /locus_tag="PKM11_01680"
     CDS             25656..26066
                     /locus_tag="PKM11_01680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47255.1"
                     /translation="MEASFEMCYDGKCATLTVEDLTRAIKNGIDREGLPDEQARRMAQ
                     HVLNFFGYSERIIDNILEPEDRDAFYQLEDTGILTTEREETTLYDGREWRIHYWLFRK
                     ERIFQLINNNGSGGACDVGAYDCYADPTAWQRTN"
     gene            26138..28036
                     /locus_tag="PKM11_01685"
     CDS             26138..28036
                     /locus_tag="PKM11_01685"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: protein motif:HMM:NF016724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HNX47256.1"
                     /translation="MELFPYPPRPNQVDFVRSVERITREGGHLVLESGTGSGKTVCAL
                     SGALQTALSTGKKVLYLTRTNSQEKQVILELRKINEKAPVFGVALQGRQGTCPLVRRD
                     KELSAGTPEELSKICRDKRRKVLEDRPGGCRFFKGLQDLDMEQFIAHCKQKLYTAEEL
                     IDHCDSLNICPHEVMKELAREARVVAAPYAYFFVPFIRNSLLDWMECPIDDVLLIVDE
                     AHNLPDYTREIESFQLSRYILEAVLKEIEEHGDPEVGKGVSLNNVRTECSRLLDEAIR
                     DYLIDEDGLIPPSFLEEGLMTAFTCTSRSLQAMAKLIMEQGEIIRESRFAQGRLPRSY
                     TFSLGTFLSYWSTLDEECFVKLVVGGENPCLKAYCIDPVVTTSAILNSGGSVHMSGTL
                     VPLNEYRDSIGLPYDSATITFPSPFPPENRKVFYVEDVSTKYEEMQSSPEMVEIMEDH
                     VVQVCNGVKRNTVVFFPSYSLMDRFLDDGVSRRISRKVYLEERNMPQLELMEVVTRFK
                     RLEENGQVLFAVMGGRISEGIDFPEDELEMAIVVGIPYPRPTAKQRALMHYYELKFRK
                     GWDYTVKGPAIRKMQQSIGRLIRTERDVGAALVLDRRITQFADRLDLVATERPLQDIQ
                     TFFRERGR"
     gene            28071..28634
                     /locus_tag="PKM11_01690"
     CDS             28071..28634
                     /locus_tag="PKM11_01690"
                     /EC_number="2.7.7.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
                     synthase"
                     /protein_id="HNX47257.1"
                     /translation="MDIPLLVLVGFWLVLPSLIPNSAATIFGGGAPVDLGRSWNGKRI
                     LGDGKTWRGLIGGISAGISIGIIQLYIAFPFDRLDYFGFGGFPENLGVIVVLAVGSLL
                     GDMIGSFIKRRLEIGRGGKAPLMDQLGFLLTSFLLAIIIFPDWFFANFWNGDGWVSLL
                     AVFLITPLIHRGVNIIGYKMGLKKVPW"
     gene            28639..29163
                     /gene="pyrE"
                     /locus_tag="PKM11_01695"
     CDS             28639..29163
                     /gene="pyrE"
                     /locus_tag="PKM11_01695"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HNX47258.1"
                     /translation="MSEELKKALEGCGAILYGDFTLASGKKSKYYIDIKRATTDPKVL
                     GLIADEMARRIEGDGFQRIAGVVLGSVPLAVALSLRTGIPFVMVRKEKKDHGTGKLIE
                     GQLNQGEKVLVVEDVITSAGSAVYAVETLRSAGAKVGTVMSVVDREEGGRDALGKLEV
                     EMRALITASKILGK"
     gene            29164..29691
                     /locus_tag="PKM11_01700"
     CDS             29164..29691
                     /locus_tag="PKM11_01700"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: protein motif:HMM:TIGR00758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HNX47259.1"
                     /translation="MPPEKDCKRCRLGDERTNIVLPCGDIHSKVVLVGEAPGAQEDLR
                     GVPFVGRAGKILDGLMAEAGLDRGRIMITNTVKCRPPGNRRPKADEMTSCRPFLQEEL
                     QGKRFVLALGLSAAEDLLGKKMVMRDVCNRPVQADLGDGLTTIMVTYHPSACIYRPAA
                     KDVLRDALKIAASYL"
     gene            complement(29682..30356)
                     /locus_tag="PKM11_01705"
     CDS             complement(29682..30356)
                     /locus_tag="PKM11_01705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HNX47260.1"
                     /translation="MQLSVIIPTMNEEESIGQVIDSVRLALSGWDFEILVVDTNSKDR
                     TREIAAEKGAVVIEEPRRGYGRAYKTGFERSQGEFIATLDADCTYPAEEIPALHKILI
                     DQNLDFITTNRFARLEEGAMSAKHRLGNFALTFTSNLLFRVKIKDSQSGMWVFRREIL
                     DRLVLSDDGMPMSEEIKIEAFRKVRSLEVPITYRKRVGEVKLSSWKDGWKNMKFLFKK
                     RFRRQR"
     gene            complement(30401..31195)
                     /locus_tag="PKM11_01710"
     CDS             complement(30401..31195)
                     /locus_tag="PKM11_01710"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX47261.1"
                     /translation="MLVSIVLKIRNEEDNISDALDSLVVQEGPIEIIVVDGYSTDRTQ
                     EIVREYGKKYPFVHLFVAGGSRGDSLNYGLQQVTADIVALTDGDCIANPNWIKEIRHC
                     IVDRGVDMVAGRSINIGLSAWEKLDRVELYNKGFDCTWPGCNLAFTRKVFETVGGVDP
                     WFVTAEDIDFNLRATDAGFSLVYNPKAIIYNRTRGTFYGFCHQAFWNGAGRKQLTMKH
                     GALWERYDPLRMFRQRMTFWAMVRLGFAWLGYFGYKFFGDEPPAKA"
     gene            31543..35145
                     /gene="smc"
                     /locus_tag="PKM11_01715"
     CDS             31543..35145
                     /gene="smc"
                     /locus_tag="PKM11_01715"
                     /inference="COORDINATES: protein motif:HMM:TIGR02169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HNX47262.1"
                     /translation="MYLKQIEVENFKSFGKKLTIPMLSGFTAVTGPNGSGKSNISDAI
                     LFVLGPKSSKAIRAGKLTDLIFNGGNAKSPANHTRVSLVFDNADRTIPLDEDIVKLTR
                     YVKLSDSGEGYNSYFYVNDRKSTLSEFDYLLASARISADGYNLVQQGDVTRIVEMSTL
                     ERRRVLDEISGIAKFDEEIVKAEVEKASAQDNIDRIAIILGELDKQIRQLEQERGAAL
                     KYLEMRDRLALAKARMAYKRKEGTEAEIKGIGEQIASYSKDIETLKVRRGELEAQIRS
                     IEDLYQKKEVELQAKGGAQFQDLKEKMDVLRVEVARAADLKERSVDQTSEVKEELKAL
                     LEEREEILRTKQAQESALAAAGTELKALDDKVRKLQKDEAKLKGELSSYDSELSVLEK
                     KIKEQDQLIRERTEALHAKGLEKERLERLAQDLLAEIEGLRQEKESAEFEVKDLDWRV
                     KELGKEGKDSSGSIRTLQESFHSKKNREGQLTKMANELETAVRNLTREYNHAKAEEEA
                     AVNVARGYNRAVKALLEARDRGEMKGIHGTIAELADVDPKYEVALNVAAGGRMQSIVV
                     DDDQVASDAINYLKKSELGRATFLPLNKMLDGRPRGKALLAEKEAAGFAIDLISYDEK
                     YRAAFWYVFGDTVVVDTLAEARRLMGGVRLVTVGGELIEASGAMVGGTSEGSKVRFGA
                     GKGKADEIGEELRKATEQADKVSTELMAIRQEIAELDSKIREIGGADRGKGVELESLQ
                     KQLNDQKARLKRVTDSAASKQAERERSLSQGAEIGLQITKQDGELTKLKAEREGNSKR
                     LLEIAPVELSQKLREAQSNVMQASQELSEKRTAHESMRMQAAERERRLGEMSATEGQQ
                     QDKLRQLDAQGKAAAEKESKIKVELSALKKIEDSMGREITALRDEKEKLLGQKGQAQA
                     DREKVMVKLETSNDFLIGMGTKRTLAEEKLKEIMQEIAQLNLEVSYPLPPLDDIRSEI
                     VLCENSLSGMGAVNLRSIEDYDEKKARHVELRAETKRLEDQRDQLVALTDQLNDKKKV
                     NLVKVFDAVNANFRRVYAELSGGGEAELLLENPLEPFQGGLVIKARPRNGKVLRLEAL
                     SGGEKSLTALAFIFALQEWQPSPFYLLDEVDMFLDAVNAEMVANRVKKSSTSAQFVQI
                     SLRKVTLNKADHIIGVTKPAGGISNVIFKPNIGDFSELEKEIGLPEEKARRDGE"
     gene            35142..36050
                     /locus_tag="PKM11_01720"
     CDS             35142..36050
                     /locus_tag="PKM11_01720"
                     /inference="COORDINATES: protein motif:HMM:NF014654.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HNX47263.1"
                     /translation="MIESGSLDNVLGHLMFHKALIDEGRGAEKIDRYLGLMRSTEGEK
                     QIAGREPLDRSLQLVFELVLSNDLDPWDVDLMKFAKLYGQRMHTEEVDFIVAGKLMHM
                     AWSILHMQSREVLSLNERREELYFGEWDTESFDQFVERPLPAIDLDVPECVELTEVVR
                     HRCTRAVSLVDLLDAFDTAQQEVEIALNRQRVREQLLKAQERFDGKSHSDDQEKDVAE
                     TWARIERCGSGPIALEDLFEDDKEDSIKVFVSLLFLARSGKISLWQDELPYGQIYLEI
                     KLPWEIAQLVDGTQAETVAIQAKMVI"
     gene            36052..36540
                     /locus_tag="PKM11_01725"
     CDS             36052..36540
                     /locus_tag="PKM11_01725"
                     /inference="COORDINATES: protein motif:HMM:NF016005.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HNX47264.1"
                     /translation="MDRAVEAVLFAASQPLRAADIADILGVGPEAVRKEIRLLDKEYE
                     ERGTAFEIAKIGQRYSLQLRQEYNQYALPFADLDMSPEVLKAASIIAYNQPILQSDLV
                     KLLGSGVYDKVRTLRQMGLVTGKHVGQSLLLSTTREFSERFGLGTKKEEIKEWMESKQ
                     KQ"
     gene            36513..36719
                     /locus_tag="PKM11_01730"
     CDS             36513..36719
                     /locus_tag="PKM11_01730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47265.1"
                     /translation="MDGIQAEAVGKAYPGWSLTRIPPTTSTYWHLRPNPVSLVSLSNV
                     EMQEDLVRCGMALSNDGWPSALKL"
     gene            36781..36996
                     /locus_tag="PKM11_01735"
     CDS             36781..36996
                     /locus_tag="PKM11_01735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LSM domain-containing protein"
                     /protein_id="HNX47266.1"
                     /translation="MVMPLALMEKTLNKKVSLLLKDNRVLEGKLTGYDEYMNMVLEET
                     EERTAEQTRRLGMVILRGNNVVSIAPL"
     gene            37004..37963
                     /locus_tag="PKM11_01740"
     CDS             37004..37963
                     /locus_tag="PKM11_01740"
                     /inference="COORDINATES: protein motif:HMM:NF012695.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NDP-sugar synthase"
                     /protein_id="HNX47267.1"
                     /translation="MKALILAGGMGTRLRPLTLSTPKPLLPLLGRPMIMHIIDSLPEE
                     VDTVVLAVSYMKDQLETFFRKNDCGRRIVLVNEDEPLGTGGAIRNVRQHLDDTFFCFN
                     GDIISSLDLRDLLSFHRRHGGIGTLSLWQVPDPSAFGVVGLDWDRIIDFQEKPAPGTA
                     ISDLINAGVYVFQPELLDHIPSGVVSLERQVFPKILDRRMHGYRFKGYWVDCGTPESY
                     LRAQSELLENGRSKNAAFMKDAKLVGLNHLDRANLDGCVIGPHVCALPGSSVGKGSLV
                     ERSVLMEGATVGRGCTVKGCLLGPGAKVNDGESVQGKILASLQ"
     assembly_gap    38119..38218
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <38219..39208
                     /locus_tag="PKM11_01745"
     CDS             <38219..39208
                     /locus_tag="PKM11_01745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HNX47268.1"
                     /translation="TMIALATMANSGGFATGPTLIGDWKHDLVDNSDLAAPLAFVSIL
                     LILVSLVLLVIIKLVIMKVHLPMGRIWPRPEKLFSRGWFPKTKDGLAVFFLVVFVLIP
                     SFFIFTYVGSVESSSFDWGPFTESLLFSFLVAGVVTVIDIALGVPLALYIAKNRTGKL
                     SEVLDVLVNVPLIVPTAALGYSLGVFWTGQNIIPTYDVLLIILAHVAFTYPLVVRNVA
                     GAVEEVDPAFEETARTLGAKPVQAFRRVLYPIIKSSILAGAIMAFTRSLGETGATLAV
                     VAKANTAPVFIVNLINEKTASGYYTAGLACIVLIIVSFMFMLALRYITNRRAH"
     gene            39208..40299
                     /locus_tag="PKM11_01750"
     CDS             39208..40299
                     /locus_tag="PKM11_01750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47269.1"
                     /translation="MPDVKLVGLRKSYGDIKAADGLDLEVKDGEYLCVLGPTGAGKTT
                     LLRMISGLLVPDKGKIFFDGQDFTRMEIEERKAALLSQTYALFPQLTVEENITFGLDI
                     RGADEKLKEQVLISMLDLVRLSGRSDAYPRELSGGMQQRTALARALASGADLLLLDEP
                     LRALDARLRISLRTELRSLVKTLKMTAIHVTHDQDEALVMADRVAVIREGRILQIGTP
                     KEVWDEPATPFVANFVGQSNFFTGEVLQSSPFTLIRTPEGTVLKGRPSELATGTTAVL
                     GVKIGNTDISKERKGYLKAKVERIIFEGRNLHVDLMMDNGQRISSKVPSWRKGKIAPG
                     DVVDVYWEESKGTVFPMPPNGLENELKVE"
     assembly_gap    40406..40505
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <40506..41207
                     /locus_tag="PKM11_01755"
     CDS             <40506..41207
                     /locus_tag="PKM11_01755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47270.1"
                     /translation="MLPGELCGGEQQKVSLARALSSGSKLLLLDEPLSALDSRVRVDL
                     RYELRRLAKELGLTTIHVTHDQEEAQSVSDRIVLMRAGTVVETGTPEELYTHPKKIFT
                     ANFIGETNLLEGWVLEIKDGVSVIELRNGGKVKVNQANHPVGDAVVISVRPEFVFQAD
                     EGMRAKVTAITYMGTYWRITANTEDEEEVAFDSVTYDENLLTIGREVYLAVNPKAAVL
                     YPRPEDGVQEAIKLE"
     gene            41200..41886
                     /locus_tag="PKM11_01760"
     CDS             41200..41886
                     /locus_tag="PKM11_01760"
                     /inference="COORDINATES: protein motif:HMM:NF013982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="HNX47271.1"
                     /translation="MSERTSLLEWFYSRRESVVSKDMRGHAQDVGDTIIEFNRAMGML
                     CRGEKEQALDALKRSFLAEKAADAREISLTEGLSRGDLEEKNREDLLHLVRRMDYAAD
                     WCKEAGMNLQLVLELNIPIPLDIWKKFNTMTLELEKMAKALKVCVDNLGLNNDLVLRT
                     HKEIEESEHAMDDMYFLMKKEFFLTNLDARAIYLMRDLLHGVENSADNFKDSADIIHI
                     LIVAQRDRPR"
     gene            41891..43240
                     /gene="glmM"
                     /locus_tag="PKM11_01765"
     CDS             41891..43240
                     /gene="glmM"
                     /locus_tag="PKM11_01765"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HNX47272.1"
                     /translation="MTKLFGTNGVRGVINQDMSVELALDVGRAIGTFMQGKVAIATDS
                     RTSADMIRALVSGGMTSAGSDVVDLGMLPTPALQYYVKNSGVKGGVMITASHNPPEFN
                     GIKCVDHDGTEMPRKKEEVIERIYGDREFATPSWKDVGNITHLAGVGASYANAISRAV
                     DRFKIGEAKLNVVLDCANGAGAVTSPGLLDTLGVRAITLNGNPQGTFPGHPSEPTPDN
                     LRDLVAVVKATGADLGIAHDGDADRTIFVDDQGNYVYGDQSLSVVASHMVQENQGGIV
                     VTPVSTSSCLEEVVKKHNGQVIYTKVGAPIVARRMMEVQAVFGGEENGGLIFPEHQYC
                     RDAAMTMAKMLEIIAIKGPLSELLKEVPRYCLDKRKLSCPEDKKEWVMEQVEAYFADQ
                     RTDATDGIKIFFEGGWSLVRPSGTEPIFRIYSEGKDEGTAKRCGDQCEKVVRQLLEE"
     gene            complement(43241..43813)
                     /locus_tag="PKM11_01770"
     CDS             complement(43241..43813)
                     /locus_tag="PKM11_01770"
                     /inference="COORDINATES: protein motif:HMM:NF013346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM165/GDT1 family protein"
                     /protein_id="HNX47273.1"
                     /translation="MDLAPLISAFILISLTELGDKTMIAVITLSSKYPKRTVFLGSFL
                     ALVAVTAVGVVIGEVLFQFVPSWIVGLAAGVVFIIFGIVTLVRKEEEEEEEVKDKGRW
                     GGFVAAFGFVALMELGDKTQLSVITLSAESGSALMVFIGASLGFLWLVVLEVSLGKAI
                     GEKVPKNYIRIGSGVVFIVFGIIFLAQQFL"
     gene            complement(43813..44664)
                     /gene="speB"
                     /locus_tag="PKM11_01775"
     CDS             complement(43813..44664)
                     /gene="speB"
                     /locus_tag="PKM11_01775"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: protein motif:HMM:TIGR01230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HNX47274.1"
                     /translation="MARSDSFALANSTFEEAEFVILGVPYDGTTRFRSGTRKAPTAIR
                     KASRLFDPYLFEHDLDVSTVKVHDAGDLDCGSSCEDMFKAVEKEATKVVKAGKFPIIM
                     GGERSITYPFVKAYQEVGVISIDAHLDFELQSDRKFDHACTMRKVADVVGIENVVPFG
                     VRSISKREIGQEMPNYVDAYQIQEGGVVNSWKKVLNMMRREHVLLSLDMDGIDPGFAP
                     GTSRPEPFGLTGYEVKRCIDMLGDRLVGFDISEVLPSHDPGTTAALAARMIMEVVAIV
                     HTRRGEM"
     gene            complement(44681..45067)
                     /locus_tag="PKM11_01780"
     CDS             complement(44681..45067)
                     /locus_tag="PKM11_01780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-5A"
                     /protein_id="HNX47275.1"
                     /translation="MSWTQQEVRELKEGRYMLIDEEPCKIINIATSKPGKHGEAKANI
                     DAVGIFDGRKRNVVYPVKHRVQVPMIDKRKAQILSISGEEVQLMDLDNYETFQLPIPE
                     EYKGQLTAGEDIMYMIAMDRRKITKV"
     gene            complement(45110..46207)
                     /locus_tag="PKM11_01785"
     CDS             complement(45110..46207)
                     /locus_tag="PKM11_01785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal biogenesis protein"
                     /protein_id="HNX47276.1"
                     /translation="MILVTKWFGVFLCEGQEVRGFKLFDKEPKLVAQKLAAVQRGEIL
                     PEEKALAVKRMKVADARLKPLGKPMVFDSSFIRPENYGLTPDMMQKVMLELGKIRVRE
                     PLSEDRSIAQAIRATDDLIEEINLLSERLHEWYGVYFPELGDFAVDAEYARLVSEMGD
                     RQVIMDHLGVSLESVGTDLVERDLDIIRGMGRTLLELYNRKESLDAYVLEGMDRVAPN
                     LSALLNPNLAARLISLAGGLQRLAKFPSSTVQLLGAEKALFLHLRTGKRPPKHGVIFQ
                     HPWINRSPYWQRGKVARSLGGKISIAAKVDAYRGEFIADKLKEQMEKRVAEIKEKYPE
                     PPRREQRQQSQQVRPQQRKGPSPKYYQNHRR"
     assembly_gap    46320..46419
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<46420..46661)
                     /locus_tag="PKM11_01790"
     CDS             complement(<46420..46661)
                     /locus_tag="PKM11_01790"
                     /inference="COORDINATES: protein motif:HMM:NF012804.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HNX47277.1"
                     /translation="MKQAGMDVVRYGRLLYEKGLTNGTGGNISARVGDMMVITPSGSC
                     KGMLDQNELVTVDIVSGKAVSGRPSMETPFHLTVYR"
     gene            complement(46658..47668)
                     /gene="mtnA"
                     /locus_tag="PKM11_01795"
     CDS             complement(46658..47668)
                     /gene="mtnA"
                     /locus_tag="PKM11_01795"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046523 -
                     S-methyl-5-thioribose-1-phosphate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HNX47278.1"
                     /translation="MKIRMDGKVSEMRAIWCEDGIVRMLDQRILPHRVEVLGFKDHHQ
                     VAEAIKDMTVRGAPAIGVAAAYGMMLAANNHEDLDKASRELKGTRPTAFDLFFAVDHM
                     LSRIRDGDDPTDSAEEYAETIVERCRLIGEHGEKLIKDGDRIMTHCNAGALATVDWGT
                     ALAPIRAAWRNGKKIFVYVSETRPRLQGMKLTAFELLNEGIPHAIIPDGASGHFLREG
                     VDMVIVGADRIAANGDFANKIGTFEKAVLAKELKVPFYTAAPLSTFDLGIKRGEDIPI
                     EYRGEEEVTVVDGVRIAPHGCKALNPGFDVTPAKYLTGIITENGVMRPQDVVRRMKGA
                     RL"
     gene            47842..48531
                     /locus_tag="PKM11_01800"
     CDS             47842..48531
                     /locus_tag="PKM11_01800"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HNX47279.1"
                     /translation="MSNPVRQKILSELQRRDLSLSEIAVLTSKAQSTLSVHLDKMVKE
                     GLIGYRDDPQDNRRKIFYVISRPVGSSVVPREELKKAVANTIGRTIGTPSTFLKGTIR
                     SIVIGMEAIGFNMDPVLKDIGRQMGAEISTRMKANDVEGLIKEVKDFYLAHELGELVV
                     FSLHPVTLIIRDEYDCSKAPDVGKTLCLLNEGILESIFEARLHMPLRVVEKDTFGTNF
                     NMCKYVIEPSL"
     gene            complement(48541..49218)
                     /locus_tag="PKM11_01805"
     CDS             complement(48541..49218)
                     /locus_tag="PKM11_01805"
                     /inference="COORDINATES: protein motif:HMM:NF013989.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HNX47280.1"
                     /translation="MKDLRVVLHIQTSLDARVTGFEIDMGAHYQLAETFEPDGTISGA
                     DTFLAAPIPDEVPEWSYEAAKNFPSCSRSVMAIVDSKGRVRNWSAIKRQPFWKTPVAL
                     CSRSTPEEYLQYLKGEGIDIIIAGKDHVDLKKALKELQSRYGLRTLRIDSGGTLSAIM
                     LKEGLVDEISVILSPCVVGNQNSAQFIDPSVAELPKPCQLKLGHVEELENGLVWLKYE
                     VIRKGKR"
     gene            complement(49292..49367)
                     /locus_tag="PKM11_01810"
     tRNA            complement(49292..49367)
                     /locus_tag="PKM11_01810"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(49332..49334),aa:Val,seq:gac)
     gene            49498..>49679
                     /locus_tag="PKM11_01815"
     CDS             49498..>49679
                     /locus_tag="PKM11_01815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47281.1"
                     /translation="MTEILLFTKPDCQKCEYVKSHLPEGVSPRIVDTSIADGLAEAAY
                     YEILHKNLPILVVDDEV"
     assembly_gap    49680..49779
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <49780..50577
                     /gene="kae1"
                     /locus_tag="PKM11_01820"
     CDS             <49780..50577
                     /gene="kae1"
                     /locus_tag="PKM11_01820"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061711 - N(6)-L-threonylcarbamoyladenine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex N(6)-L-threonylcarbamoyladenine
                     synthase Kae1"
                     /protein_id="HNX47282.1"
                     /translation="RSGLKFKDIGLVCFSKGPGLGPCLRTVATGARALSLSLNVPIVG
                     VNHCISHLEIGRIKTEAQDPVLLYASGGNTQVIAFANGRYRIFGETLDIGIGNMLDKL
                     GREIGLGYYAGPKIEKAAAQGSKLLELPYSVKGMDMAFSGILTAAVAHRNKGESLEDI
                     CFSVQETCFAMLTEVTERAMAHVEKEEVLLGGGVVQNKRLQRMVLDMAEARGARMYVP
                     DRTLCMDNGAMIAWTGLVMHNAGIVHSMETTTIDQRFRTDQVEVTWR"
     gene            complement(50564..51862)
                     /locus_tag="PKM11_01825"
     CDS             complement(50564..51862)
                     /locus_tag="PKM11_01825"
                     /inference="COORDINATES: protein motif:HMM:NF014342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HNX47283.1"
                     /translation="MRECTEARVFSHNDADGIGAASVLTSMLVRAGKGSQTTMLKSFD
                     LPAIQASLVKGVDLLIVADMGSSNLTALESLGVKVIVLDHHRPEKDSDKVMHLNPAVL
                     KVDGARYACASTLAMLLAVTVEEGNWDLLPLSFAGMVGDRQHMQGLSGVNAHLFNEGS
                     KRNLVQEKKGSLLPPGPIGEGLMRTSHPFIRGVSGDAQGITRLLQEANVRPESTWDGL
                     DEGGKRRLSSLISLRLLEQGCSLGSLEDELAPDYFFPQDNSRAYQLTRLINACGRVDE
                     TALGLSMLLGEKESRERADSLLKEYDEMLLNAAKRTAERGVSKEIAIQHFESQQREVS
                     SELCGLVMQWIGDQDKATICLTRMDKEFKVSSRGTRKLVDKDGLDLSVAMRDAAASVG
                     GVGGGHNIASGASIPLGKDIDFIQALDAIISKQMNRVSAK"
     gene            complement(51930..52388)
                     /locus_tag="PKM11_01830"
     CDS             complement(51930..52388)
                     /locus_tag="PKM11_01830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HNX47284.1"
                     /translation="MARMHARRRGSSRSRRPLLTENPEWVPLSNEEVVQMVVKLGKEG
                     MTSSKIGLVLRDQHAVPSVKLATGKTVLEIMNENGLTPKLPEDLMALMRKAINLNLHV
                     QNGNRGDHSNRRGLQLVESKIRRLVKYYKNRDILPADWNYSLKNAELLIE"
     gene            complement(52467..52844)
                     /locus_tag="PKM11_01835"
     CDS             complement(52467..52844)
                     /locus_tag="PKM11_01835"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HNX47285.1"
                     /translation="MTRLPNVYAIGFQGDRFLMVYNPKRVGWEMPGGKLEEFETPLDG
                     IKREYREECGFDLEVLDCRPMGPVVVFAGVLGKEVGEGEMGWELMNELPQNLAFPECE
                     YREQIAWAREAVRNKLGKALTLK"
     gene            complement(52928..53605)
                     /locus_tag="PKM11_01840"
     CDS             complement(52928..53605)
                     /locus_tag="PKM11_01840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrillarin-like rRNA/tRNA
                     2'-O-methyltransferase"
                     /protein_id="HNX47286.1"
                     /translation="MGEAKFRIEPTSFPGVYRSGDMVLTKNLAPGKRVYGERLFSQED
                     EEYREWSPDRSKLGAFIRKGGSSFPFKPDSHVLYLGASSGTTPSHVSDLAPEGRVYAV
                     EISPRMFRDLVGVCEERPNMMPILGDATKPDDLAFLVEKADVVYQDVAQKNQAAMFAK
                     AMKRFSAPYGMLAVKARSEDVTREPRDVFQDAANYLRKEGFKVVEIVDLEPFEKDHAM
                     IVVERAS"
     gene            53658..54113
                     /locus_tag="PKM11_01845"
     CDS             53658..54113
                     /locus_tag="PKM11_01845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47287.1"
                     /translation="MAGEEEAKRIQELTERIAQLEEAIRQVSVPYGQLAAQLATFQDT
                     VGKYFRLMDLYQRYGVVSVDTILPEVKDPISKDILRILLDHPDLNISQLTDELKGRRG
                     SSSRRIVREKLNELAEMKLVVEETGRNERSYRLSEDVVKRWSQVLGLTK"
     gene            54210..54491
                     /locus_tag="PKM11_01850"
     CDS             54210..54491
                     /locus_tag="PKM11_01850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47288.1"
                     /translation="MSDNDMPDPEQLRQMFTVLTEQVPPLLDSITKVLYGAQEGTKFG
                     ESVAAFYKALRDAGMSNEQAFELTKDYMSNLSLGGMLKNIVSGASKDHD"
     gene            54500..54757
                     /locus_tag="PKM11_01855"
     CDS             54500..54757
                     /locus_tag="PKM11_01855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47289.1"
                     /translation="MPRTEKQKKDGQAIIYIAAAVPGLLISLGIAYLRMRKRAKKEAR
                     RFFLTLVRDGVPVPQAKELADIYASSISLTEMIREMGPFTS"
     gene            complement(54747..55658)
                     /locus_tag="PKM11_01860"
     CDS             complement(54747..55658)
                     /locus_tag="PKM11_01860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47290.1"
                     /translation="METDIIHEQGEQKNWNESFYFSFYDRGNDICGFMRLGLKPNKNE
                     KMLFCFFMMPDGSLVGTKDTVEFDGATLNAKGLTFTKVEDEKVWNLTFDGELPAHKKG
                     EDTVAKVKFDLRFEGTNPMFNYRECVTADKEALAASVASEHLEQMGKVLGSLKVDDRD
                     YYIKGLGERDHSWGERDWTAPRAWVWLTCQVSEDFGFNVTKLYMDKGDIDAGFLYVDG
                     ENLPLVKVDMVTEYDADGSPNTLYMAMYDKDGVVYGVKGEVKKKAIMEFKGENDRGSI
                     MFETLTKWRIDDGEDAGYGIAEYLFRK"
     gene            complement(55664..58282)
                     /locus_tag="PKM11_01865"
     CDS             complement(55664..58282)
                     /locus_tag="PKM11_01865"
                     /inference="COORDINATES: protein motif:HMM:NF013491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HNX47291.1"
                     /translation="MGEQVISLSAKGDIEEIGGKARNLMDLLAAGFPVPEGWVVSTSA
                     YEQFLDRNGLRQRISEALKDLDHQDAVKVVRCAESIRGWMMAGELDPMLAGQLFDRTE
                     TFGPSGLWAVRSSAIAEDTEQASFAGQQDTYLNVTRERLAESVKKCWASYWNDRAIEY
                     RHDKGVSHLDAGMAVVVQRMVNADSSGIMFTSDPITGDEKIVIESSWGLGESIASGLV
                     TPDRFVCDSSTGEVKESKINSKAQAIFLSPEGEKVVDVPESERNRPSLTRGKVELVAK
                     LGIQLHKHMGSPQDIEWAAEGDKIYLLQSRPITTIGGDLTLWTRGYGDEYWADVTSPL
                     FFSLLGPWLTEYVNWEGSAIMGYKELTNKPLLKIHKGHVYFNAEVLEGMLMYNPKFSR
                     TKDLLNYFPERDQQRIANAEFRTGKRVLAMLRTTVLDWDGNILRTDKAYKRWARRFMR
                     WAEEFDVRDLTTIPDDKLEDVVWEMEKELIKHYRLIRYGMVGHSIGMNMIMKRWLQDW
                     IGDDKGVLYSRVISGLKGNKTIETNIALNHLANAARSDPHVLGKVLGLSSAEVLVQMR
                     SDEKMSNYAKEFDSFLKQYGHRSHTREVYFPRWGEDPRLVADIVRSLASSPPVDLEEL
                     ERRKIREREEVEKEILGKIRKIKRGWLKARMFKTVMGFAQTYLMFRENQRYYLDHILY
                     RQRRVYMEFARRFLEKGIIAKQEDIFFLSKDEIFALAKGEGKEALTKIPERRKEFVDW
                     KGELPPKFLKGVVEFDDTVKMVENSAQLTGTSASPGVATGPVRVVDSIEQLSEIREGE
                     ILVTSNTDPGWTAVFSKIAGLITETGGILSHGAVVSREYGIPAVTAVKGATKIFITGQ
                     RITLDGNEGLIYIREG"
     gene            58393..>58737
                     /locus_tag="PKM11_01870"
     CDS             58393..>58737
                     /locus_tag="PKM11_01870"
                     /inference="COORDINATES: protein motif:HMM:NF012673.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0046855 - inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HNX47292.1"
                     /translation="MRETLEWLAAEVAGRIDQECAFSDRAAEVGMGADGTPTCLIDQI
                     AEDLLLELMDKRNVPLNVLSEEAGFIDRGHERTLVMDPVDGTYNSLMGIPFYSVSLAV
                     CTKSMNDATHGIV"
BASE COUNT        12007 a        17327 c        17187 g        11816 t
ORIGIN      
        1 ccgatcatgc tgaacaccgt ttcagcatga ttgcgcttcg ccgtcagggc ggcgaagcgc
       61 tgtgggaact gcttggcgaa gaacaccagc ttgttgtagt tgacccgatg ctccatcagg
      121 cctttagcat tcttcttgat cttgtgcagc ggcgtcgccc cgtgcagcct ggccgcggcg
      181 aggcatgcct cgccgtggta ggccgaatcg gccaggctgc ggacgggaac gatgttctcc
      241 ggtaacttca tccagacatc cgagaacacc tggctgtcat ggacgttaga ggcggtgagc
      301 tcgtagctca ggatcaggaa ccgatccacc tcgatggcag cgtgcgtttt cacccagtcc
      361 tcgttcggac ggtgcgcgta tggcgtctcg cgccatccgc gcttgcgacc ggagtaaccg
      421 gtcgcatcgg tggcgacgat gacgttcctc ttcggtagat tcccgataac gaacgagaag
      481 aaccgttcca gcagcgatgt ccagcgttgg ctggacatcg ccctgcagag cacggaatga
      541 tccggtaccc gttcgatttg aaagtaccag ctcagcatgt tcagcagacc ttccgcatcg
      601 cggaatgttg tgcggaatag ttgctggata agaaaaccta tcatgatcgt tctttcattg
      661 gaagagggtc ggccgaccct cttcctgcgc tgccagaacg ggaacgaatc gacgttcttc
      721 cgaatgcctt ccatggccag ctgcaaccgg tgcgcctcga cctcggagca tcgaccaagg
      781 tcgatgctga aggtgtcgag gcgcgattga ccgtcaaact tgaatatctc ggatgttatt
      841 tctacgaccg tggcaaccaa tccagtcacc ttccttaagc agctggcgaa tggattggac
      901 cacacttaaa tattttgtaa acaatattga taacaatata aattaattag aattcaattg
      961 tttggcgttg gcaaagtgtc ggttggaatt ttgcaacaag gcccacctca ataatcgaca
     1021 gataacgatt atatatggaa gcgatttctc ttgcttacag gattcatatg gaagatgctg
     1081 gttcagacga aataaaattc aaaaaactta ggcggttcaa cctgataatg gggttcttcc
     1141 acttcattca ggccgccatt atgctggcga tcgcgaacta cgatgtccag atgaggttca
     1201 ccacctctta catcgacgcc ggaatgggat tccctccgac cggacctggt tccgcagaac
     1261 tattgttcag cgtacccctg ggccccatgg tggccatatt cctgctgatg tcggccatag
     1321 cccacttctc ggtgtccacc ttcggttacg ggtggtacgt taagaacctc aagatgaaca
     1381 tgaacaaggc ccgctggttc gagtatgcgg tctcctcttc gttcatgtta gtggtcatcg
     1441 cctggctgtg cgggatgttc gacttcatat cgataatgtt gctcttctcc cttaacgcct
     1501 gcatgaacct gttcggctac atgatggagg cgcacaacca gaacaccaag aagaccgagt
     1561 ggacctcgtt catcttcggg tgctttgcgg ggctcatacc ctggatagcg ctgttcatgt
     1621 acttcaccgg cgttcgcggc ggttcccctc cggacttcgt ctacggcatc atgatctcga
     1681 tcgcgttctt cttcaacgtg ttcgccatca acatgatcct gcagtacaag aaggtcggaa
     1741 agtggaagga ctacctgtac ggcgagaggg tctacatcat cctgagcctg gtggccaaga
     1801 ccgccctggc ctggcaggtg ttctccggga ccatggtggc ctaggaccaa accacttccc
     1861 tttttccttt ttttttatgt tacgtacctt ctgaccggcg tatgctggac cagtttcccc
     1921 tcacaaagga cggagaccgc tccgtggcct ccgcacacca ggcacttccg tccgtccgat
     1981 ctcttcgatt cttccatctc catcaaacgc agcagcgcct tgcgctcctt ggaggccttg
     2041 acgctgtcga cgttcaccga ggtcatgagg ttcttggcca aggtggcgaa gtccctgcgc
     2101 tcctcggtca ggctctcgaa gttgatcagg ctgtccccgg tgaacagtac cagttcctcc
     2161 ggtaggaagt agaacacctg gccagtggtg tggcctccga aaccttccag cacctcgcag
     2221 cgcattcccg ccaggtccaa ggtggccagg accggaaagt cccctcgttt tcccgttgcc
     2281 ttcataggat agacgtccgg gtgctcggcc accgagaacc tcgaaaaaag attgatgagc
     2341 ttggtgtaga cctcggcgag caccgaccct tcgctttccg atccgtacgc ccggtccgag
     2401 cgcctgatca tctccagagt gtccgggtgc atccggacgg tggcgtcgac cagcccggcg
     2461 gaaccggaat ggtcggcgtc accatgggtt atcaggacgt tccgcaccag gcccaccccg
     2521 ccccagccct ctctttccat gagcttgtcc aggtcacgga agtagatgcc gaagccggta
     2581 tccaccatgc tcacctccga accgttccgg aggaggtagc aattaccgcc gcagggcagc
     2641 tggacgcaaa gaaggtccac cttgcccagg catacctctt gcagatcggc gtagaagcca
     2701 tctccggagg tctcccgcag tccccgaccg ctgcgcagca catccgagaa ggcctgcttg
     2761 gggtcgcttc ccaggttcat gagctcctgg gccacatggt tgatgtccga cagcaatctc
     2821 agcaggaacg catcctcggc ctcgcccacc agggcgcgta gctcctgagc gaagcgaata
     2881 tagaagaccg tatcatctag atgctgaccg gtcgtatcgt attccaggat ctccagcgga
     2941 tagatcgatt tcagcttttc caacaggcgg tccaccgctc ccgcctcctc caccgtcaag
     3001 gagacggtca aacgctcggg atgttttccc cgatcatcaa aatcaaggaa atctatgttg
     3061 catttcgccg cggtggtatg gttcaggaaa tcgaacagcg ccccgctgct gttcggcaga
     3121 acgacatcga acttgaggaa gctgggcacg accatcttcc cctgcaggta gccgatggcc
     3181 tgcaactcgg agcgcatggc ctggtactcg tcctcgctgc agcgggcctc gaagaaaacc
     3241 gtgtaagggt cgatgcgctt gtcatactgg atgcggtcga tgttgcctcc gtggcgcttg
     3301 acgatctccg ccgcccggtg caaagctcct ggctcgtcgg gcatcttggc cacgaagtag
     3361 tgcctctcca tcatcggaga ggatgcgcct aaaaaactta taacttaggt tcccacccgg
     3421 tcagcaggct ggacggaaag cctcacttca tcttggcggc catgctgacc gccaccttga
     3481 gctggttcag gatgcagggt tccacataat atcccttcat ggtacgaagc tcgccgtaca
     3541 tgtcctccgg cgagcggccg ataagttcct tgaccgatct tatgcccagc atgtacagcg
     3601 gctcggccac cttctcccct acgattggga tggtccgaag ttccttcagc gctgactccc
     3661 ggtcgtcctg ctccatcgtg gggagcatgg tgccccttgg gatataatcg ttttcgaccc
     3721 atcacgggcg aagctggctg gccttgcgga ttattacccg cacggattgg gtgacctgtc
     3781 cctcatccag catccctatc agcaggtagc tgaaggtgaa ggcgaagtac ggggctaggt
     3841 atatccaatc gaagggaacc acgattatca gtatcaccag ggcgaagtcg ctgaaggggc
     3901 ggtaatgcag gaagtactcg accgctcggc cgaggtcccg accgtgggcg aaaccatcgg
     3961 ccagctcgtc caccgcaccg gcgatgagga acaccaccaa tggcagaagc atgacgtcca
     4021 ttccccagat gaacccccct atcaagaagg tcattaggcc caccagggtc ccgatcagga
     4081 agctaaagtt atctatcttc ttggtgacca ccaggctgat gagcatggcc aggaagaacg
     4141 cggtggagaa tcccccgtcc accaccatga cccctcccat gaccagtccg gagagcacgg
     4201 ccaggagctt ggcgatcctt atcgatccga tgctctcgtc ataggcctga tcgatgtact
     4261 ttatcgcccc gccaagaaag gcgtaggaag ccaccagaac agcgattcgg aggggtacgt
     4321 cccccactat agctagcgtc tcgagcgtgt gtattactct cctgatcctt cactgccttg
     4381 ggaaagcatc agagggattt tattttataa gtgttgcgct aaaaaatggt gcccgaaccc
     4441 cctattacgt cagatgacga taaattactt cgataaaggg gcctggaacg gcattttaag
     4501 gttccctgat gaacaattgt cgaaccccga gatcacgcgt cgatcggacg ttcaatatta
     4561 acggtgtaaa agttcgattc tagacaaata atattttaac actgataatt ggagtctggg
     4621 actcaaaaag tacttatata cttcaagtca atcaaaacct tcagtcccag tggggatcgg
     4681 aggtggttta ccgatggcaa agaaaccgga gaagaaggcg gaccctaaga agaagaagta
     4741 agatcttctg atcttcaccg atatttttcc atgccagggc ggatcgtcct ggcgtccttt
     4801 ccatttcttt tttatcatta aatactgcga ccagcttctt cgtggtcgca tgaagtggcg
     4861 ttctcacgta tccatcggca aggccatcgc cgacgtgttg gagctgcctc caggagagcg
     4921 caaggccttt cttgacggta tcgtcgaacc ggaccgtcac aaggagaggg tcagcggtcc
     4981 cggttattcc taccgggtca gccatcatca tccaagacgc agggtgttca tgcttcacgt
     5041 ttggatggcc agaaggtcat tcctccgcaa caacagctac cagggctatc gccacctggg
     5101 catggcattg cattatctcc aggacaaatc aacgtccaaa gggttcatgg gtctatcgca
     5161 cgatcgccgg gaggaggcac tggccgaggt aaaggtgccc atggaggcca tcgaaagggg
     5221 tttcaacaag tacctgtcca atcccgagtt cgtgtcgagg tccctggaac ttaccaaacc
     5281 gttgaaggat gtcgatcaga taatggccca ggcctcgttc cgatcggcgg cggtggccgc
     5341 tgcggtgacc gacctcagaa gaccgtccgg actggaaagg aagcttcggt ctttgcaccg
     5401 aagacgcctg ttgctccacc ttcccctgtc gatcggcgcg ctcgccgtcg gctcctccct
     5461 ctccttggcc tggtggaacg ccataccgtt cgccatggcc atcgcaatct ccctcatcgt
     5521 gttggtgatg gaccgcccgt accgccagct cagccgggtc gccttgtggc atggtctgaa
     5581 gagtcattaa ggaccaacat gcccataacc aatgacgatg ttcgagatgg tccccggcca
     5641 ccagggccga tggcgcacgc ttcgagaagg tgaaggccga ggtccagtgg tgtactggat
     5701 gagcagggac cagcgtctgg aggacaactg ggcgctttac catgcctggg ccagggccaa
     5761 gagtgaaggg cgttccctgg gcgtattgtt ctgcctggca cctgatttcc tcgccgccgg
     5821 tccaaggcat taccgtttca tgctgaaagg gctggcggag accatggatg cggcggaaag
     5881 ggcgggcatt ccgttcttcc tgctggaggg agacccgtca gtggaagtgc cgcgtttcct
     5941 gcgggaatgg aacgtatctt tgacggtcac cgacttcgat ccattgcgcc agaaatcgga
     6001 atggagggcg gcgaccatgg agggttgcga cagcggcttc gaagaggtgg acgcgcataa
     6061 catcgtgcct tgttggatcg catcgccgaa gcaggagttc gccgccgcca ccttccgtcc
     6121 caagatcaaa cgtcatctgc cggaccggct ggaacacctg tcgccttccc cgtccaagtt
     6181 cggtgaatgg cccggggatg ccgggacgaa gtacataaaa aagatcatcg ccagatacaa
     6241 agaggtggcg gacgaccgtt gggaaggagg gcctgtccag gctcgtaggg cgttgagcga
     6301 gttcttgcga gatcgtcttc ctgggtacgc ggagagaagg aacgacccta acctggactg
     6361 ggtctctcaa ttgtcgccct acctgcattt cggcatgata tcggcgcacc gggtggcctt
     6421 ggcggtgatg gccgccaccg ctcctcagcc ggacaaggac gctttcctgg aagagctgat
     6481 cgtgcgccgg gagctctccg acaacttctg cctctacaac cgcaagtacg attccacgga
     6541 agggttcccg gcctgggccc gagccacgtt gcgggaccac ctggccgacg aacgggagta
     6601 cgtttacgcg gaagaggagc tgggcaaggc gaacacccac gatccgctat ggaacgccgc
     6661 ccaggtccag atggccaccg agggaaagat gcacggctgg ctgcgtatgt actgggccaa
     6721 gaaagttctg gaatggacag agaccccggc cgaagcgttg cgcatcgtca acgcgttcaa
     6781 cgaccgctac gagatggatg gtcgggaccc gaacgggtac gtcggagcgg cctggagcat
     6841 cgggggcgtt cacgaccggg cctggaccga gcggaagata ttcggcaagg tccgttacat
     6901 gaacctgaac ggagcgtacc gcaagttcga cgttgacgct ttcgtcgaaa gatatgtcaa
     6961 cccagatcga tgaccttgcc cttctccggt aatagcgtcc tcaccgggca ctgttcagcg
     7021 aacatctcgg gatgggcgca gtgcaccggg accactaact ccggggatat cttcttcacg
     7081 acgttccaaa ggtcggcgac cgccagatgt ccggagctat ggaacccttc ctcgaaatcc
     7141 agatttccat cgattttcga gatgccgcgg caatcgaacc ccatgagctc gatccagttc
     7201 atcagcttct gcaggttgtc cgtctgccgc aggtcgtagg ccatgctgtt agagtaaacg
     7261 tacgtcccac cgttccagtc caggtcgagc atcttggtca tgtcccagaa ggaaaggcat
     7321 aacatgtgct ccttcggtcc cttggcgatg tcgtccgggt cggcgacctg ccatccctcc
     7381 ttctgcagat catccacgat gtccacttcc ttatcggaga gggaccggta cacccacagg
     7441 gagtccttgc gcacgttccc gtcgaccttg gatatgctct gcagcaatgc cacgtcctta
     7501 tgggtgacca ccatccgttt tcccgttcgc cgggcgatgt cgatgaacgt atcaagccgc
     7561 tcaaagttgt tggcggagaa gtccgcgatg gtcagtccac ggccgttctc caccgccgcc
     7621 aggcagttat cgtgcaccat ccgctcggtc atctcccttt ccggcgccgg tcgcccgatc
     7681 ctggtcccct ctatgatcag ggccttgggt tgaagcgatc cagcctcctc cgcgaagcgg
     7741 acggtgtcct gcccgtgcgc cccatgcatt cggaggtccc cggaatagac tatccattct
     7801 ccttcgttcc ggcgcagggc gtaggccgtg gcgccataga tcgaatggtc caccgggaag
     7861 gacaagtact cgatcccatt cagctcaccg catccagacg ctacttggca ggaaccgccc
     7921 ttcttccatt ccggggcctc atccaccggt tcgccggtca ggacccaatg gcgtccttga
     7981 acctccttat ccttggttcg ggtcgacacc agtatgcggg gctccatctc cttacgggac
     8041 ctgaccacat ggtcgaacag ctcggtggac atgccggtcc tccctatctc gctcgacgcc
     8101 ctcagtatgg cgtaggtcat ggggctggac acgatcggga tgtcatgccg caggaacccg
     8161 gcgttcccgt aatgatcgaa atgggcgtgg gacaggaaca gcgcgtccac tctggccgga
     8221 gccatgtccg tcagcggaag gtccaccggg tagaggtccg gccggtaaca atccaggagg
     8281 gggagcattc ccaattttac ataatcccgc aggccgcgcc ccgtcctagg ccgcacgaac
     8341 tccgaacagt acaggtttcc tatgtcgaac ggttccccga agtccaggaa ggcgccgcgg
     8401 tcgcccaggt ccacatgtat cttgttgcct ccaacgactc ccgcgcctcc atggacagtg
     8461 atcctcatgt gaacggcctt cgaacgggct ggcaggattt atcgctatct cttgttcggc
     8521 aacggcggtc gatctgccta aaaacgaata taatgcaagc gtattgaagg gacatggcag
     8581 ccatgacctt cgcccagaag gttctatcaa aggccagcgg aaaggaagcc catccaggtg
     8641 acatcgtgtc ggccaagatc gacctggcga tgtcccacga gaacgccgcc ctggtgctgc
     8701 gttctttcaa agagataggg gccaaggagg tctgggaccc cgagaagata gttctccttt
     8761 tcgatcaccg catcccggcg aacacgacca aggccgccga aggccaccag tcggtacgaa
     8821 agttcgtgac cgcggaaggg ctgcctaact tctacgatat gcgcgagggg atatgccatc
     8881 aggtgctccc tgagaagggg catgtcctcc cgggcatgct gatcgttggt acggactcgc
     8941 acactaccac ctacggggcc tttggagcgt tctccaccgg tattggcgct acggagatgg
     9001 ccgcggtgtg ggccaccggc gagctgtgga tgaaggtgcc gcagacgttc cgtttcaatt
     9061 tgaatggtaa gctggacgac caggtcgccg ccaaggatgt catccttcat ctgatcggca
     9121 agatgggggc ggacggatgc gattaccgct gcgtggagtt cgccggtccc gtggttaacc
     9181 acatgtccgt gtccggtcga atgaccatgt gcaacatgag catggagatg ggggccaagg
     9241 ccggcgtgac gttcccggac gagaagacca gagattacct gaaagggcga acgtccaagg
     9301 aattggtacc ggtgacctcc gacaaggaag cggaggtcga gaagatcttc gatatggacc
     9361 ttactggact atcaccgcag gtggcctatc ctcattccgt cgataacgtg aagccggtgg
     9421 aggagatggc cggcattcca gtggaccagg ccgttatcgg ttcctgcacc aacggccggg
     9481 cggaggacct gctggccgcg gagcggattt tacacggccg ccacattccg aacagcgtgc
     9541 gtctcatcgt cgttcccgcc tctcgtgagg tctacctgtg ggcggcggac agcggtatac
     9601 tcgcctcgct agtgaggtcc ggagccattg tcaccaaccc cggttgtggt ccctgcctgg
     9661 gggcgcatca gggccttctg gctccgggcg agagatgcat cgccaccacc aaccgcaact
     9721 tccgtgggcg gatgggatct ccggaatccg aagtgtatct cgcctcgcca gctaccgtgg
     9781 ccgcttccgc cctgaaggga cagatcgccg atccccggga ggtgagggtg tgaaaggcaa
     9841 ggtctggaga tatggcgatc acgtcaacac cgacgtcatc attcccgggc ggtatctgga
     9901 cgactacgac ctcaagaaca tggccaagca tgccatggag gacctcgatc ccaagttcgc
     9961 caaggatgtc acgtacggtg atatcatcgt ggccggtcgc aacttcggct gcggctccag
    10021 tcgggagcag gcgcctctgg cgctaaagca cgccggcgtg ggtgcggtcg tcgccaccag
    10081 cttcgcccgt atcttctacc ggaatgccat caacatcggg ttgccggtca tcgagttcga
    10141 tgccaccggg atgttcgaaa agggcgatgt ggcgttgatc aacatggaga agggtatcgt
    10201 cgtcaacgag accagcggtc gcaccagcaa gttcgagccg ctcccgccgt tcctgctcga
    10261 gatattgaag gagggaggcc tggtccccca ctccgccaag aggttccgtt agggcaaggt
    10321 atattaaggg gcaatgtttg ggtggggaca aggacgctcc agaactcccc ctaaaaccct
    10381 caaaaaggat gtctggcatg ccctgtacag gtcgtgaaaa aatttataag cccctcgcta
    10441 atatggggac actccccctg gtggtgaatt catgaagtat actagatttg agaaggcgcg
    10501 cataatcggt gccagggcac tgcagatatc ccttggcgcg cctgtgcttc tcgagatccc
    10561 cgaagggatg atcgatccga tcaacatctc tcagttggag ttcgacaagg gagtaatccc
    10621 gataactgta aaacgcgaca tatgaggtta ttaaaatgag cgacgagtcc aagaccgagc
    10681 ttctcgtacc ggaggacgtt taccttactt ccggtgttca cattggcacc cagcagaaga
    10741 gtgctgacat gaaggatttc atcttcaagg tcaggaccga cggtttgtac gtcatggacg
    10801 tcaaacagac cgacgtccgc atcagggctg ctgccaagtt cctatcccgc ttcaagaccg
    10861 accgcatcct ggtcgtgtcc gccagacagt acgggcagaa gccggtccgg ataatgtcca
    10921 aggccatcgg ggccatgtac ttcgaggaga ggctcatacc cggttccttg accaacccgg
    10981 tcctgaaccg cttcatcgag cctgacgtca ttgtggtcac tgaccccgcc gccgatcagc
    11041 aggccgtggc cgaggcgttg aacgtgggca taccgatcgt ggccctctgc gacgccaaca
    11101 atgagacgag gaacgtcgac ctggtcatcc cgaccaacaa caagggtcgc cgctctctgg
    11161 cctgtgtcta ctggctgctt acccgtgaga tcctgaagga gcagggtaag ctgaccaggg
    11221 acgaggattt caagctgggc atcgacgatt tcgaagccag tctttaaacc ccaacccttt
    11281 taaccccctt tctcttattt tctcatatgg tccgccgagc ggccgtcgcc ggtcagttct
    11341 actcatcgtc aagaagcgcc ttgatcaagg agctggagca atgcttcctt tctcccctgg
    11401 ggcctggtga actgccggag gtcgtcaagg atggtccgag gaatatcgtg ggggcggtgg
    11461 tcccgcacgc cggactggtg ttctccgggc cggtggcggc gcatgtctac gcggagatgg
    11521 ccgccgatgg gatgccggaa acggtggtca tcatcggccc gaaccacacc ggtcacggca
    11581 aggcagtctc ggtcagcagc gaggacttcg aaacgcctct ggggatcgtc agatcggacc
    11641 gggacatcgt atctcggctg aaaggcgtgg tagagatcga ccgcgccgcc catctttacg
    11701 agcacagcct ggaggtgcaa ttgccattcc tgcaatatct ggacccggag gtgaaggtcg
    11761 tcccgatcgt catggggcgt caggacctca tcatggccag ggagacggcc aaggtcctag
    11821 gtgaggcctg cgccggtaag gatgtggtga ttctagcttc ttcggacctc tcccattacc
    11881 tcccggccgg ggtggccagg aagagggacg agatggtcct ggaacgcatc ttgcgcctgg
    11941 acgcggaagg tctgatcgac gtggtcgaga ggaatgatat cagcatgtgc gggtccggtc
    12001 cggtggcctc catgataatg gcctgtaaag gaggcaaggc caggcttctg cattacggca
    12061 attcgggaga cgtacgaccg atggacgagg tggtcggata cgccgcggcg gtcgtggtaa
    12121 aatgaccgta ccctcgatgt tataaatata tacgaattga catttactca atagccccca
    12181 gaggggccat tcgaaggatg agattcacat ggatggaaca aagacgtgtc cctactgcgg
    12241 gaagttggcc aacgccgact cccagttctg tcagggttgc ggaaggagca taagctcccc
    12301 gccccagtac tctgagcaac cgcctcagca gtaccagcag tctcagaact atcagcagcc
    12361 acctcaacag tacgaccagc cccctcagag gggcggatgg caggagcccg ccccagccta
    12421 tggggcaccg gcctacggag cgcctgcccc accttacggt cagtcgtacg gcggagccaa
    12481 gggccagatc gcgggagcga tacagaaccg tggtgtgacc gacgaaatca tgagcggcat
    12541 atgggtattc tggccgattt tgacgatcgt gctaggcgtc atcatcatgg tagcgctgac
    12601 gatcttcatc ggatgggccg gtctgataat cggtctggta atagccctgg tgatgtactg
    12661 cgtcctgaac ttcaaactgc tgaagcggat ggacgagcac cgcaagcgcg agatggcgtt
    12721 gcgcatggcc ataatagcgt ttttaaagga gaagggagcc gagacccagc gggcccagct
    12781 catcgtgaac gagatatccg ccctggagag catcaaccag gaggcgatgt acaaggagaa
    12841 ggagcggacc ccgctgctct ggaccatcct cggcgtgctg ccgatcctga acctaatcgt
    12901 aatgtacttc ctggccgagt tcccgttcga ccacgacaag cgctggcacg cattcaccca
    12961 gtacacccag gccgcctgcc agaagctggg catcaacatc atgaccccct cctggagcac
    13021 catcaaggag aggccgaacg tgctgttcct gatcctgacg cttctgttca gcatcgtggt
    13081 cttcgtctgg tactacttca tcatcaagga cctcaacgag cacttccagg cgcagtggca
    13141 gttcgaggac cagttgatgg cgcagctccg ctgaaacctc ttccaattct cttttctttt
    13201 tacccgaaat atctcagtgc attgaattcc attttgactt atgtttccaa aaattatata
    13261 tgaacggcat tttaattagt tccagaggtt cattttatgg acaatcaaat gaagtattgt
    13321 ggcagctgtg gaaatcaggt cgatgtccga gctgagatct gccccaaatg cggcataaga
    13381 gtgagccaag aaggtggtgc tcgaggtggc gcgaccatat tctgccagca ttgcggaaat
    13441 caaatggacg tccgagcgga ggtatgtccc aagtgcggta taagggccgc ccaaacgcag
    13501 ccccagtacc agcagcaacc tcaaccgcaa taccagcctc aaccgcagcc ccagtaccag
    13561 cctcaaccgc agtatccgcc tcagtaccct ccgccatatc agcccccagt cgctcaaaag
    13621 agcgagggcc tggccgcggt gctgtccttc ctcattccgg ggctaggtca gatgtacaac
    13681 ggcgagatag ggaaaggaat actgttcttg atcctggcgt tcgtgttcgc agccctgatg
    13741 atcgtgctga tcggtttcat actctatccg atcctgtggt tgtatgggat atacgatgcc
    13801 tataacacgg ccaagaagat caaccagagg aacgcctatc cgggccagca gtaccaaagg
    13861 ggttactaaa caccttcttc cttccttttt ttaaaaaaat aaagaaaagg gttttttaaa
    13921 tttttctcat cttaccgagc actggctcgt atacgaagcc cttgtccagc aatgagttgg
    13981 ctatggagtc catctcctcg cgctcgatgc cctgggactt gcccttctgc accacttcgt
    14041 cccaggccgc tccctttccg gagtccaggc tttcgatcat ggagagcacc aaagcttcct
    14101 tgtccacgtc gtcctgctcc tcttccaggt cgatctcttc cggagcggcc gaatcgagat
    14161 gcacgtccgg tccggtatga tactccggta gcaggaactt cagcgcgtcg gaggtcatgc
    14221 ccttgtagcg ggtcaggtcc tcttgttgat agtgccgcag gctgtgcacg gtgccttcgg
    14281 ccaaaggccg ggagaacccg atctgcatga gcttctccac ggtcggttcc accagcttca
    14341 tggcctcttc catggccgag atgcggtcca tagtggcctt gcatgtttct aggacccagc
    14401 cgtcgcggac ggacgcctcc accttaccga ccctctccgg gcgtatcgat acgtacatct
    14461 tgccctcctc cggagagtag gtacggaact ttccgaccac cgccacgaag cagggcggct
    14521 gcaacttggc cagggccatg gcggcctccg gctggtactg cccagcggtc atgtagaacg
    14581 ttcccgtggg atcggttatc ttggcccgcc acaccggttc gttctcgttg cctacgttat
    14641 cgttgtccgt gaggacgccg acaacgaaga tgcggttgat cttcgcaccc aacggggata
    14701 tgagatagga aggggtcttc tcgccctctc ccttcatctc caggctggag gagttgaact
    14761 ccgccgcgaa gaccctccag gccacttccc tggacatcaa ttgaatccct ccatatcggt
    14821 aagcagtttg gcgccctcct ccctcacgtc gacctccagg aacctggcgt cccgggcgat
    14881 cagcatcggt ccgaagtcgt ccgagcgcac cattccccgc acctccaggg tccgggcgaa
    14941 cagcttctcc tcggccatct ccttgacggc ctccggattg cgctcctcgg tggtgatctt
    15001 caccgcctcc tctatgctga tgttcaggag ctgctcggta agctccttcc cgaacaccac
    15061 gctcatggac gacgttccat cgtccaatat ggacttgatc ctcaggtcgt cggtcccctt
    15121 gacctttccg tgtacgcggc aggtgctctt ctgcagcacc cgtcggcagt cagggcagcg
    15181 catgaccagg ccgcttccct cgcgcacatc gactagggtt cctcgaacca caacgtccat
    15241 ggcccctccg gacagctcca catcctctaa ggttctgacc ttgggaacgc tgctcgacag
    15301 gtcgccgaga gttcctttgg acagcatttg gatctccgcc ttatcgccga ggttcagctt
    15361 gggcatgccc ttccagctct tgacgtaggc gcctactatg cgcacctcgt ccccatcctt
    15421 cagctcggcg tccttccaca cggtgatctc cgcgcttccc gtgtcgtcgc tcaatacccc
    15481 ggtgacgatg gtcttcttct ctccggaggc ggtgatctcc cgcttctcgg gacggctgac
    15541 cttaccggag atgaccacgt agttcatccc atcggccaga tcggctatct tgacctcggc
    15601 ggagccgcca ccggacggca tgtccgccac gtccaggatc tcctcggact cctcgaccga
    15661 ggcccggttc cccaggttca gctggggagt tcccttgtac tccttggtgt aagcgttacg
    15721 tatgagaacg gtggagccct gcttcagctg cacgctctcc gtctcccaga ccgtgtattg
    15781 cacccgtccg gactcatcgg ccatgtaccc gtaggcgatg ctcttgtgcg ccccgcccac
    15841 ctcgatggtc ttggggttca cggtgagcac tttgaccagc aggtccacgg actgttcgtc
    15901 cccggtcagc tcggccacgc tcttacgtcc cgatccgtcg ttgaaagcgt ccgggttacc
    15961 gcccatcttc ttcagtatgt ccctcttggc ccactccaag gtgacccggt agaggttgac
    16021 gtacttttcc agttcttcag ctatcttgtt cttgtccgct ttttccccga gcaccctggc
    16081 aagttcttcc acgtggggtg cgagctcttc tctgtccatt tcatgcctcc gttccttagc
    16141 taataaggca ccacattatg cccgttacgt ttaatagcat tattcaccgc ggattgaaaa
    16201 tgaaaggctg gccggcaaac aagttggatt gccagcaaaa agaaaggatg ccgggagccg
    16261 ttgaaaatgg ctcactcggt gaaggtctcg ccgcgctcgt acttctcctt caggtgggag
    16321 atgagtatgt cgcggttgtt gcgcaggtgc gactcgtacc aggcgagcac gacatcggcg
    16381 agcttctcgt ggaagcggtc catgtcgaac ttggagagcg gagagtcgaa gaccacgaac
    16441 tgtccgaata tccgcttcca tccggcgtac ttgtagtaat gttcgccctc gcaataatcg
    16501 aagaccatgc gcatgtaagg cgtggaatcg acggcatagt acatgacctt cagggaatcg
    16561 cccatgcgcc cctgggtctg tgtacggtcg accagctgca cgcggttgac cgcctcgaag
    16621 tcatactcgt tcttgaaccg ccacttgagg gggaactcct cgaactgggc gaactcgctg
    16681 taagttggct ccatgttcaa ttgcacgttg atgcgggaga accggttcag aacgttccag
    16741 aaatctccga tgatggcgcg gttgatcgtg gtcttctgga agttgatctc ttccttgtcc
    16801 ttggagatgg catcggtacg ggccgaaagc tcggcgtcca acttggcgaa ccaatcttcg
    16861 tcctttgcct taccaacctt cttttctgca accatcggag tctcctctgg cataattgcc
    16921 atacaaccat aaaaagatat ctcattccta taataaccca gcataggagc tggcgttatg
    16981 gcctccaaga taagcttttc taatcggagg tcataatccg gacgatggac gtagcggggg
    17041 gtctgacctc gttccttgag caggttcagg gcgacccttt ggtctattcc gtgctgttct
    17101 tcatctacat aatagcggcc accttgttcc tgcccattcc ggtggagctg atgctcttcc
    17161 tgagcccggc cacccccttt ctgttgaagg ccattctgct gggggtcggc aaagcagtgg
    17221 gcagcatgat cgttttctac atcggcatga acgtggaagg accgatcaac accctgacca
    17281 gaaaatgggg tttcttccga atggtggtca acttcagtaa atggctggtc gacaagctcg
    17341 gttatctcgg tctgtacatc atactgagca tccccataat ggtggacacc gttcccgtgt
    17401 acctgttctc catattccgc aaggaccgct gtgaccgcga tctgcgccta ttcgccctga
    17461 ccaacctggc cgccggcatg accagggcgg ctatcgtgta ctttgcggtc accgagctgg
    17521 gattaggcta tctatttggc atttagaaag gtttatatct ctcaagaaaa ttttgaggta
    17581 atggtcccga agaacaagat actcaagatc cttgacgagt acgacaagaa gaagctcacc
    17641 gtggccacac tgtgttctca ttcctctctg cagatcttca acggggccaa gaaggaaggc
    17701 ttccgcaccc tgggtctcac ggtcaaggac aacttccgtt actatgacgc gttcccgctc
    17761 ggccgtccgg acgagttcat gaagttggac agttacgccg atcttctgga caacgtggac
    17821 gagctgcttg ctcgcaatat aatcgtagtt ccgcacggct ccttcgtgga gtacatgggc
    17881 accgagaagt tcgagaagat gcccgtgccc accttcggga atcggaacgt tctccgctgg
    17941 gaatcgcacc gcgacaagat gagggagtgg ctggagaccg cggggatcgt catgcccaga
    18001 gtgatcgacg accccaagac cattgaccgg ccagtgctgg tgaagtataa cggggccaag
    18061 ggcggtcgcg gcttcttcat cgccaaggac tataacgagt tcaagatggg cctggacctg
    18121 gatcaggact acaccatcca ggagtacata ctgggcacca ggtactatct ccattacttc
    18181 ttctcgccga tcaagaagga tgggttccga gtgggcgacg gctcgttgga gctcatgtcc
    18241 atggaccgcc gagatgagag caacattgac gaactgtaca agttgggcgc gtccgaggag
    18301 ctgaagaagc tcggcctctt cccttcgttc gtggtcaccg gcaacgttcc ggtggtcatc
    18361 cgggaaagcc ttctgcccaa ggtgttcgac atgggcgagc aggtagtgaa gcgctcctac
    18421 gaactgttcg gcggcatgat cgggcccttc tgcctggaag gcatcgtcac cgacaaactg
    18481 gagttcaagg tgttcgagat atcgtcccgg atagtcgccg gctcgaaccc cttcatctcc
    18541 ggctcgccgt actccgacct caccgaggag aacatgagca ccggtcgccg tatctctcgg
    18601 gagatcaaga acgcggttct caccgacagc atggaccagg tcatatctta aaaacgacaa
    18661 aagaggccgg ggacctcccg gccttttaat ttttattaaa gtttaccagc cgcgctcttg
    18721 catgcgctgt tccttggcca gggtggagat ctcgatgcca tgcatggcct ccccaagtcc
    18781 cctggacacc tcggctatga ccttcgggtc gtcgaagtgg gtcaccgctt ccacgatggc
    18841 cttggcgcgg atcgccgggt cgttgctctt gaaaatgccc gagcctacga acacgccatc
    18901 ggaaccgagc tgcatcatta gcgccgcgtc cgcgggcgtg gcgataccac cggcggcgaa
    18961 gttgatgacc ggcagccttt gcatcacggc gacctccttg accaggtaga acggcgcctc
    19021 gatctgcctg gcgatgaccg ctagttccgc atcgtccttc cccttcagct cgcgcacctt
    19081 gcccatgatt atcctctgat ggcgcacggc ctcgatgatg ttcccggttc caggctctcc
    19141 cttggtccgg accatggccg ctccctcgtc gatgcgcctt agcgcctcgc ccaggtcctt
    19201 ggccccgcaa acgaacggta cggtgaaccc tttcttgacc acatgcatga acggatcggc
    19261 cggggtgagg acctcggact cgtcgatcat gtccactccc agggtctcca ggacctgcgc
    19321 ttcgacaaaa tgcccgatgc ggcacttggc catgaccggt atggtcacgg cgtccattat
    19381 ctccaggacc ttgaccgggt cggccatcct ggccactccg ccctgggccc ggatgtccgc
    19441 cgggaccctc tccaaggcca tgacggccac cgcgccagct tcctcggcga tccgggcctg
    19501 ctcggcgttg gtgacgtcca tgaccactcc gccctgctgc atcttggcga atccgcgctt
    19561 gaccagctcg gtcccatgac gcagtccgga taggtccaaa gtaaatgcca tttagctcac
    19621 caaaccggct tacctgcagg ggtttattta tcccttttcc caaaccgtcc cagtaaagtt
    19681 ggcaaactgc tctcagaaaa gcatatagac attgccttcg ttcatcggct cgatgttcgc
    19741 gaacaggatg gagaacgtcc tcgagtctgg cacggtcaag atagccaacc tggtaagcaa
    19801 gctcaaggag gagggggcgg acatcatatc attctccatg ggggaaccgg acttccatac
    19861 ccccgacaat ataaaagagg cctgcgttcg cgccttggcc aacgatttca cttactacac
    19921 cccgtcggcg ggcatccccg aactgaggaa ggccatagcc gagcggtgcc ggaccttgaa
    19981 caacatacct tgcgaggcgt ccaatgttct ggtgaccccg accaagcagg ccatattcat
    20041 gaccatgttg gccatggtcg acgatgggga cgaggtcata gtcccggaca tctcctgggg
    20101 aacgttcgag gcctgcgccc atctggcggg cggcaaggtc cgccactgca agatatccgc
    20161 ggaccagggg ttccgcatga cgccggagtc ggtggcggaa aggataacca aacgcaccaa
    20221 gctgctggtc ctgaactccc cttccaatcc ctgcggcgcg gtgctcacca aggacgatgt
    20281 gaagggcatc gccgatctgg ccaaggacca cgacttctac gtgctggcgg acgagatcta
    20341 taaccagctg gtgttcgagg gggagcacac ttccatatcc tcactggacg gaatgttcga
    20401 gaggaccata accgtggacg gtttctcgaa gacctacgcc atgaccggct ggagggccgg
    20461 ttgggccgtt gctccgaaga acatcttcaa ggaactgaac aagcttcaga cccagtccat
    20521 aacctgtgtc acctccttcg tgcagcaggc ctgtctggag gccttgcggg gtccgcagga
    20581 ctccgtggcc ctcatgaaga aggagttcaa ggcccggcgc gacctggtgc attccctcat
    20641 tcaggacata cccagtctga actgcccgat gcccagcgga gcgttctaca tcatgccatc
    20701 ctacgacttc gacatgaaat cggaggacat ggccgcttat cttttgaacg aggcgcacgt
    20761 ggccgtgacg cctggatcag cgttcggacc ggccggggaa ggacggttcc ggctgtccta
    20821 cgccgccagc cgggaaaata tcagggaagg catgtccagg gtcaagaccg ccttggcgaa
    20881 gttgtgatca ttccggcggc agaaggttcg gtatgccgtc ctcgatgaca taggccacat
    20941 cgcatctggt gcataacagc cggccctcaa cgatctcatc ggcatccgcc ctctccacct
    21001 gcagttccaa aggatgatgc ttgcagaccg ggcaggccag tatatcaacg aggtccttct
    21061 tcatctcccg ttcaaggaca tgggcggata tcaacctttc accatgtctg gtcgctaact
    21121 atttatctag ttctccgcat cgagcgcccc ggagagattc acatgcgccg aattgacctc
    21181 aggagcgaca cgttcaccct gccttccaag gagatgctgg acagcatacc gtccgctgat
    21241 ctgggcgatg acgtggaggg agaggacccc acggtgaacc aactgcagga cctggccgcc
    21301 agcatgttcg gcaccgaggc cgctctgctg gtctccagcg gcaccatggg caacctggtc
    21361 tccctgatgg cccactgccg ccggggcgac gagatcatac tggagtccga ggcgcacatc
    21421 tactattacg agctgggagg catgtccgcc atcgttggcg ccatcccccg gctggtccaa
    21481 gggacgcgcg gtaagttcac cgccgagcaa ctggaggcgg cgatacgcca cccggacctt
    21541 cactatccca acactcgctt ggtgtgcatc gagaacaccc acaaccgcgg cggcggcatc
    21601 gtttggaccc cgaaggaagt agaggcggtg gccaaggtgg cccacgacca tgggctcaag
    21661 atgcactgcg acggcgcccg gatattcaac gccgccgtcg ctctggacgt cgacgtcaag
    21721 gagtacatga agcacctgga cagtctgagc ttctgcctct ccaagggact ggcctgcccg
    21781 gtcggctcga tcgtggtcgg taataaagag ttcatggaag aggtccgccg caaccgcaag
    21841 atggtcggag gcggcatgcg ccaggcggga ataatcgccg ctccaggtct tatcggcctg
    21901 cagaagatgg tcggccggtt gaaggaagat caccgcaacg cccgccgact ggcggaggga
    21961 ctgaacgaaa ttcccggcat caaggtggac atggaggcgg tgcagacgaa catcgttctg
    22021 gccgacatca ccggcaccgg ttgggacgtg gactatttcg tcaaccgggc ctgcaagatc
    22081 ggcgttcagg tgttcgagtt cggggccacc aaggcacgtt tcgttaccca ttacggtata
    22141 gacgaacagg acgtggatga cgccttggcc cgcctgcgcc ggctgttgga acgctagtct
    22201 atggaaacct attttatctg tggttttcta ccctctcagg ccgcgatcgc atcgaccgta
    22261 aggtctgccg gtggaaaggc agagaaatca tatcgagcga tgcgcattca ccatgaggga
    22321 tcgatttgag cagaagactt ttcacggtag gtccggtgga ggtgttcccg gacacgttaa
    22381 gttccatgaa caggggaatg atggtccacc ggggcaagga ctaccaggac ctgcagcacg
    22441 gcgtagtgga gaagatacgc aaggtgctgg acattgacag cgagatttat ctggcgcccg
    22501 cctcagcctc cggattcctg gagggttgcg tgcgctccgc cgtagatacc aagatggccg
    22561 gtctatccaa cggttccttc ggagaccgct ggcagctcat tggccaggag aacggcaagc
    22621 aggtgcagaa gatcaacggg gaatggggaa aggccctgcg cgccactcat ctggcaggaa
    22681 agctggagaa ggacgtggag gcggtaacct tcgtctccaa cgaatcatcc actggcgtac
    22741 tgaacccgac cggggagata gtggacgaga tacggaagca gggcgacgcc ctgataatgg
    22801 tcgacggcgt cacctccgta ggggctgtgg acctcaagct acgaaagttg gacctggacg
    22861 ccctggtctt cggaagccag aaagcgttgg cattgcctcc gggactggcg gtggtctgcg
    22921 tttcctcacg attaatggag aaggccgcca aggtcaagaa ccgcggctat tacctggacc
    22981 tgatccagta caagaagttg gctgacaagg accttcctct gaccacaccg ccagtttcgt
    23041 taatgtacgg tctggactac caactggaca agatgctcaa ggagggcgtg gcgaaacgtt
    23101 acgagcgcca tcagcgcatg gccgacatgg tgcgcggctg ggcgatggaa cacctaggtc
    23161 tctacgccga ggacggtttc cgctcgaaca ctatcagcgt tataaagctc aacggcctgg
    23221 acttcaagga gttcgacaag cgcctgaggc aaaagggatt tgaggtctcg cccggatacg
    23281 gcaacgtcaa ggacgagacg ttccggatcg gccacatggg cgatctcacc gagaaggaca
    23341 tccaggacct actggacgtc atggacgaaa cgatggagga gatgaaatga aactcttagt
    23401 aaccgacgaa ctgtcccagg aaggcctgga gatgctgacc aagggctccg gggtccaggt
    23461 ggacgtcaag ccgaagatac cgcacgagga gctgctgaag atcatcggcg agtatgacgc
    23521 tctcatagtc cgcagcggca ccaaggtcac cgccgaggtc atcgaggcgg gaaagaagct
    23581 gcgcgtggtc ggcagggccg gcgtgggcgt ggataacgtt gacgtggagg cggcgacccg
    23641 ccgcggcgtg ctggtgatga acacccccgc cgccaacatc atctccgctg cggagcacac
    23701 catggccatg atgttgacgt tagcaaggaa catcccccgc gccgacgctt ccgtcaagtc
    23761 tggcaagtgg gagaggagca agttcaccgg cgtggagctg atgggcaaga ccctgggcat
    23821 agtcggcatc ggacgcgtcg gtggcgaggt ggccaagagg gccaagtcct tccagatgaa
    23881 gctggtcggt tacgacccgt acatatctca ggagctggcc gtaaagctgg gtgttagaat
    23941 actgccgctg gacaaggtcc tggaggaggc ggacttcata accatccaca cccctctgac
    24001 gcccacgacc catcacctgc tgggcaagga gcagctggcc atgctgaagc cctccgcact
    24061 catagtcaac tgcgcccgcg gcggcatcat cgacgaggac gccttgtacg aggcgctcaa
    24121 ggccaagacc atcgccgggg ccgccctgga cgtgttcgag gaggagccgc ccaagggttc
    24181 caagctgctg accttggaca acctggttgc gaccccgcac ctgggcgctt ctaccaagga
    24241 ggcgcaggag aaggtgtcca tcgagatggc cgagcacgtc aagatgttcc tggtggacaa
    24301 caagatcacc aacgccgtca acgtgcccat aagccgcgtc gaccccaagg tatctccgtt
    24361 catcgggctt gccgaacggt tgggggcgtt ctgcgtccaa ctctccgatg ggccggtgaa
    24421 gaagatcgag gtggaatgcc acggggagat cgccaaccta gacactcgca tggtcaccat
    24481 ctccgccata gtcggggtgc tgtccatcgt cgtgggggag agcaccaata taatcaacgc
    24541 caccagcatc gcccgggaga agggcatcca gatagtggag accaaggtgg acgagagcag
    24601 ccactacacc aacatgctgg tgctgcgcat atcctccgac ggtcacaagg ccgaggtccg
    24661 gggcaccgtg ttcccgtccg acctgtcccg catcatcggg gtggacgagt tcgacctcga
    24721 catgccgttg gagggcgact tcctgctcac caagcaccac gacatgcccg gtatgatcgg
    24781 caagatcggg accatcctgg gcaagcggga cataaacatc gcccgcatgg gcgtgggacg
    24841 cgccgacaag ggcggcgacg ccctgatgct catctccgtg gaccaggagg tcgggaaggc
    24901 ggtggtggcc gagttccggg ccctgccgaa cttccacgag gcccgctcca tagtgctgag
    24961 ccacatgcgc acccgggaat acatgaacat ctgagcccgg gaaacgcctt ccatcaaccc
    25021 tttcttattt tttcctccac gctgcgcacc ttgcgctcca tgtccgccgg gcggtccctc
    25081 cggtcatcga tcttgatgtt ggtcaccacc cggtcgctca tcgaaagcac ccgggaatgg
    25141 caggccatga tggtggccat caccttttcc gcatcccctt cgagaacggt ccccatgggc
    25201 gtcaactggt gcttgagccc gctagcctcc acgatcctca ggcactccgc gacgaacggg
    25261 ctgaggctaa ctcccgcccc tatcggtacg atcgagaact cggcgatcaa actgctcacc
    25321 tataccaaat tgtgttctcc tgggtcaagt actttatctt cttcgaaata tatattatgt
    25381 ggtaattatt aaaatctaaa tggattgcca ttcatttttc aaatatttag cagatttcaa
    25441 aaagtattta taacacgtaa ggggtgagaa aagagtaatt gcatactttg ttgcactgtt
    25501 actaaggaga tttctgaatg aaaaatgtca gcaaggataa atctcgttct tttccgttgg
    25561 caggcaaggg agccagaaag tcggtcccct accccatcat tgaagacgtg aacgccagcg
    25621 gtttggatgg tttgggtggt tcgggggcta atggtatgga agcttctttt gagatgtgtt
    25681 atgatggaaa atgcgcgacc ttgaccgtgg aggacctgac gcgggccata aagaacggca
    25741 tcgatcgcga ggggctgccg gacgagcagg ccagaaggat ggcccagcac gtcctgaact
    25801 tcttcggcta cagcgaaagg atcatagaca acatcctgga gcccgaggac cgggacgcct
    25861 tctatcagct ggaggacacc gggatactga ccaccgagcg cgaggagacc accctctacg
    25921 acggcaggga gtggcgcatt cattactggc ttttccgcaa ggagagaata ttccagctga
    25981 taaacaacaa cggcagtggc ggggcgtgcg acgtgggcgc ctacgactgt tacgccgatc
    26041 ctacggcctg gcagagaacg aactaggccg tgaccaaggg cccactttcg gtgggcccgg
    26101 ggcaacaatt tttattaggc atcagttctg actcggcgtg gagctatttc cctatcctcc
    26161 ccgtcccaat caggtcgatt tcgtgcgctc cgtcgaacgg atcacgcgcg aaggaggcca
    26221 cctggtcctg gagagcggta ccgggagcgg aaagaccgtt tgcgccctgt ccggggcctt
    26281 gcagaccgcc ctctccacgg ggaagaaggt cctttatctc acccgcacca actcccagga
    26341 gaagcaggtc atcctggaac tgaggaagat caacgagaag gcaccggtgt tcggcgtggc
    26401 attgcaaggc cgtcagggca cctgccctct ggtgcgccgg gacaaggagc tgagcgccgg
    26461 aacgcccgaa gagctgtcca agatatgccg ggacaagcga cgaaaggtcc tggaggaccg
    26521 gccgggaggt tgccgcttct tcaaaggcct gcaggacctg gacatggagc agttcatcgc
    26581 gcactgcaag cagaagctct acacggccga ggagctcatc gatcactgcg actcgctgaa
    26641 catctgcccc cacgaggtga tgaaggaact ggcgcgcgag gccagggtgg tcgccgcgcc
    26701 ttacgcctac ttcttcgtac cgttcatacg aaactccctg ctggactgga tggaatgccc
    26761 catcgacgac gtcctgctga tcgtggacga ggcgcataac ctgcccgatt atacgaggga
    26821 gatagagagc ttccagctct cccgctacat cctggaggcg gtcctgaagg agatcgagga
    26881 gcacggcgac ccggaagtgg gaaagggggt gagcctgaat aacgttcgta cggaatgctc
    26941 caggttgctc gacgaggcga tacgggacta cctgatcgac gaggacggtc tcatcccgcc
    27001 ctccttcctg gaggaaggtc tgatgaccgc cttcacctgc acctcccgct ccctgcaggc
    27061 catggccaag ctgatcatgg agcagggaga gatcatcagg gaatcgcgct tcgcccaggg
    27121 gcgtttgccg cgctcgtaca ccttctccct gggtacgttc ctatcctact ggtccaccct
    27181 ggacgaggag tgcttcgtca agctggtggt cggcggggag aacccctgcc tgaaggccta
    27241 ctgcatcgac ccggtggtga ccacctccgc catactgaac agcggcggca gcgtgcatat
    27301 gtccggcacc ctggtccccc tgaacgaata tcgcgactcc atcggacttc cctacgattc
    27361 ggccaccatc acctttccat cgccgttccc cccggagaac cggaaggtgt tctacgtgga
    27421 ggacgtctcc accaagtacg aggaaatgca gtcctccccg gagatggtgg agatcatgga
    27481 ggaccacgtg gtccaggtgt gcaatggcgt caaacggaac accgtggtgt tcttcccatc
    27541 gtactcgctc atggaccgtt tcctcgatga tggggtttcc cgacgcatct ccaggaaggt
    27601 atacctggag gagcggaaca tgccccagct ggaactgatg gaggtggtga cccgcttcaa
    27661 gaggctggag gagaacggcc aggtgctctt cgcggtcatg ggcggccgca tcagcgaggg
    27721 gatcgacttt ccggaggacg agctggagat ggccatcgtg gtcggcattc cctatcccag
    27781 gcccacggcc aagcagcggg ccctcatgca ctactacgag ctcaagttcc gaaagggctg
    27841 ggactacacg gtgaagggac cggcgataag gaagatgcag caatccatcg gccgtctcat
    27901 ccgaaccgaa agggacgtcg gcgcggcgtt ggtcctggac cggcggataa cgcagttcgc
    27961 cgaccgtttg gacctggtgg ccacggaacg gccgctgcag gacatccaga ccttcttccg
    28021 ggagcgggga aggtagaaag gttgataacc gaccggaggg attcgcgcct atggacatcc
    28081 ccctgctggt cctcgtggga ttctggcttg tgctcccttc gttgatcccc aactcggccg
    28141 ccaccatatt cggcggcggg gcaccggtgg acctcgggcg ttcctggaac gggaagcgga
    28201 tactggggga cggaaagacc tggcgcggcc tcatcggagg gatcagcgcc ggtatctcga
    28261 taggcataat ccagctttac atcgcgttcc cgttcgaccg cctggactat ttcggtttcg
    28321 gcggtttccc ggagaacttg ggggtgatcg tggtgctagc ggtcggctcg ctgctggggg
    28381 acatgatagg ttctttcata aagcgccggc tggagatcgg gcggggcgga aaggctccgc
    28441 tcatggacca gttggggttc ctgctgacct cgttcctgtt ggccatcata atattccccg
    28501 actggttctt cgccaacttc tggaacgggg acggatgggt gtccttgctg gcggtgttcc
    28561 tgatcacccc actcatacac cgcggggtga acatcatcgg gtacaagatg gggctgaaga
    28621 aggtcccctg gtgatcatat gagcgaagaa ctgaagaagg cgctggaagg ttgcggtgcg
    28681 atactctatg gggatttcac cctggcctcg ggcaagaaga gcaagtacta catagacatc
    28741 aaacgcgcca ccaccgaccc caaggtgctc ggtctcatcg ccgacgaaat ggctcggagg
    28801 atcgagggtg acggttttca acgcatcgcc ggggtggtgc tcggctccgt cccgttggcg
    28861 gtggccctgt cgctccgaac cggcataccg ttcgtcatgg tccgcaagga gaagaaggac
    28921 cacggcaccg ggaagctcat cgaaggtcag ctgaaccagg gcgagaaggt actggtggtg
    28981 gaggacgtca taacctccgc cggttccgcc gtctacgcgg tggagacgct gcgttcggcc
    29041 ggcgctaagg tcggcacggt catgtccgtg gtggaccggg aggagggcgg gcgggacgcc
    29101 ttgggcaagc tggaagtgga gatgagggcc ctcatcacgg ccagcaagat tctggggaaa
    29161 tgaatgccgc cggagaagga ctgcaagcgc tgccgtctag gtgacgaacg aactaacatc
    29221 gttcttccct gcggggatat ccattccaag gtcgtcctgg tcggtgaggc ccctggcgct
    29281 caggaggacc tccggggcgt tccgttcgtg ggaagggccg gaaagatctt ggacgggctg
    29341 atggcggagg ccggtctgga ccgcgggcgg ataatgataa ccaacaccgt gaagtgccgg
    29401 ccgcccggca accggcgccc gaaggcggac gagatgactt cctgccgccc attcctgcaa
    29461 gaggagctgc aaggaaaacg cttcgttctg gccctgggcc taagcgccgc cgaggacctt
    29521 ctgggtaaaa aaatggtgat gagggacgta tgcaaccggc cggtgcaggc ggaccttggc
    29581 gatggtctaa caacgataat ggtgacgtac catccgtcgg cctgcatcta ccgcccggcg
    29641 gccaaggacg tgctccggga tgctctcaaa attgcggcgt cctacctctg acgccggaag
    29701 cgcttcttga aaaggaactt catgttcttc caaccgtcct tccagctgga caacttgacc
    29761 tcgcccaccc tcttccggta ggtgatcggc acctccaggc tgcggacctt gcggaacgcc
    29821 tctatcttta tctcctcgga catcggcatt ccatcgtcgc tgaggaccag acggtccagt
    29881 atttcgcggc ggaacaccca catcccgctc tgtgagtcct tgatcttgac gcggaacaac
    29941 aggttggagg tgaaggtcag ggcgaagtta ccgagccggt gcttagcgct catggccccc
    30001 tcttccagcc tggcgaagcg gttggtggtg atgaaatcca ggttctggtc gatgaggatc
    30061 ttgtgaagcg ccggtatctc ctccgccgga taggtgcaat cggcgtccag ggtcgctatg
    30121 aactctccct gcgacctctc gaatccggtc ttgtatgctc gtccgtaacc gcggcggggc
    30181 tcctcgatga ccaccgcgcc tttctcagcg gctatctctc gggtacggtc cttggagttg
    30241 gtgtccacca ccagtatctc gaagtcccag cctgacaggg ccaaacgaac gctgtcgatg
    30301 acctgcccga tggactcctc ctcgttcatg gtgggtatga tgacgctcag ctgcaagttc
    30361 ccgcctcctg ggtataacct cggtccgact aataatgctt tcaggccttg gccggaggtt
    30421 catcgccgaa gaacttgtat ccgaaatatc caagccaggc aaagcccagg cggaccatgg
    30481 cccagaaggt catcctctgg cggaacatcc tcaacggatc gtaccgctcc cagagcgccc
    30541 catgcttcat ggtcagctgt ttcctccccg ccccgttcca gaacgcctgg tggcagaaac
    30601 cgtagaacgt gccgcgggtg cggttgtaga tgatggcctt ggggttgtac accaagctga
    30661 acccggcgtc ggtggcccga agattgaagt cgatgtcctc ggcggttacg aaccagggat
    30721 ccaccccgcc caccgtctcg aagacctttc ttgtgaaggc gaggttgcag ccgggccagg
    30781 tgcagtcgaa gcccttgtta tacagctcca cgcggtccaa cttctcccag gcgctgagcc
    30841 cgatgttgat ggacctgccg gccaccatgt ccacccctcg gtccacgatg cagtggcgga
    30901 tctccttgat ccagttgggg ttggcgatgc aatctccgtc cgtgagggcg actatgtccg
    30961 ccgtaacctg ctgcagccca tagttgaggc tgtccccccg ggaccctccg gccacgaaaa
    31021 ggtgcacgaa aggatacttt ttaccgtact cccgcacgat ctcctgggtg cggtcggtgc
    31081 tgtatccgtc cacgacgatt atctcgatag gaccctcctg caccaccagg gagtccaggg
    31141 cgtcggagat gttgtcctcc tcgttcctga tcttgaggac gatggatacg agcatcctcc
    31201 ctttatccgc gtcgcaccta taaaacctcc ttgcgggacc agcttagctt tttaactggg
    31261 acggcgttag gagctgtcag acaatgcgtc acatacggac gccgacccca cataacacta
    31321 ctggcacaaa cgaacggaaa ggtcaatatg aaaaatgacg ggccggcaga gggttcgcaa
    31381 ctacctgttt ttctcctctc tggacattaa attccaggtc ataaattata tatacgcaac
    31441 ataatataca taatatgtcc gacagctgtc ggactcggga tgggatgcac tcgagcgaag
    31501 gcgagtggga tggaacacct tcgcgccccc aggtagtgtc gcatgtatct taagcagata
    31561 gaagtagaga acttcaagtc cttcggcaag aagctgacca taccaatgct cagcggtttc
    31621 accgccgtca ccgggccgaa cggatctgga aagtccaaca tttccgacgc catccttttc
    31681 gtcctggggc cgaagagctc caaggccatc cgggccggga agctcaccga cctcatcttc
    31741 aacggcggga acgccaagtc cccggccaat cacacccgag tttcgctggt cttcgacaac
    31801 gccgaccgaa ccatcccgct cgacgaggac atcgtgaagc tgaccaggta cgtcaagctc
    31861 tccgattccg gcgaaggcta caattcctat ttctacgtca acgatcgaaa gtcgaccctg
    31921 tccgagttcg attacctgtt ggcaagcgcc cgcatcagcg cggacggcta caatctggtc
    31981 cagcagggag atgtcaccag gatagtggag atgtccaccc tggagcgccg ccgggtcctg
    32041 gatgagatat ctggcatcgc caagttcgac gaggagatcg tgaaggccga ggtggagaag
    32101 gcctcggccc aggacaacat cgatcgcatc gccatcatac tgggggagct ggacaagcag
    32161 atccgtcagc tggagcagga aagaggggct gccctcaaat acctggagat gagggaccgt
    32221 ctggctttgg ccaaggcccg catggcctac aagcgcaagg aaggcacgga ggccgagatc
    32281 aagggcatcg gggagcagat cgcctcctat tccaaggaca tcgagaccct gaaggtccga
    32341 cgcggggagc tggaggccca gatacgttcg atagaggacc tctaccagaa gaaggaggtc
    32401 gagctgcagg ccaagggcgg agcccagttc caggacctga aggagaagat ggacgtcctt
    32461 cgcgtagagg tggccagggc cgccgacctg aaggaacgat ccgtcgatca gacgtccgag
    32521 gttaaggaag agctgaaggc tttgctggag gagcgcgagg agatcctccg gaccaagcag
    32581 gcccaggagt ccgctctcgc tgccgccggg accgaactga aggccctgga tgacaaggtc
    32641 aggaagctgc agaaggacga ggccaagctg aagggcgagc tgagctccta cgacagcgag
    32701 ctgtccgtcc tggaaaagaa gatcaaggag caggaccagc tcatccggga aaggaccgag
    32761 gcgctgcacg ccaaaggact ggagaaggaa aggctggagc gcctggccca ggaccttctg
    32821 gcagagatag agggcctccg tcaggagaag gagtccgccg agttcgaggt caaggacctg
    32881 gactggcgcg tcaaggagct gggaaaggag ggcaaggatt ccagcggctc cataaggacc
    32941 ctgcaggaat cgttccattc caagaagaac cgcgagggcc agctgaccaa gatggccaat
    33001 gagctggaga cggcggttcg caatctcacc cgcgagtaca accacgccaa ggccgaggag
    33061 gaggcggcgg tcaacgtcgc ccgcggctac aaccgggccg tgaaggcttt gctagaggcc
    33121 agggaccgcg gggagatgaa gggcatacac ggcaccatcg ccgagctggc cgatgtcgat
    33181 cccaagtacg aggtcgccct gaacgtcgcc gccggcggtc gcatgcagtc catagtcgtc
    33241 gacgatgacc aggtggcgtc cgacgccatc aactatctca agaagagcga actggggcgg
    33301 gcgaccttcc ttccgctcaa caagatgctg gacggccggc cgcggggtaa ggcgctcctg
    33361 gccgagaagg aggccgccgg attcgccatc gatctcatca gttacgacga gaagtaccgg
    33421 gcggccttct ggtacgtgtt cggtgacacg gtggtcgtcg acactctggc cgaagcgcgc
    33481 cggttaatgg gcggcgtacg cttggttacc gtcggcggag agctgatcga agcctccggg
    33541 gccatggtcg gcggtacctc ggaagggagc aaggtccgtt ttggcgccgg aaagggcaag
    33601 gcggacgaga tcggcgaaga gctgcggaag gcgaccgagc aggccgataa ggtctccacg
    33661 gaactgatgg ccattcgcca ggagatcgct gaacttgatt caaagatccg cgagatcgga
    33721 ggggccgacc gcggaaaggg cgttgaactg gagagcctgc agaagcagct taatgatcag
    33781 aaggcccggc tgaagagggt caccgactcc gccgcttcca agcaggccga gcgggagagg
    33841 tccctgtccc aaggggccga gatcggtctg cagatcacca agcaggacgg ggagctcacc
    33901 aagctgaagg ccgagcggga gggcaactcc aagcgcctcc tggagatagc cccggtcgag
    33961 ctgtcccaga agctaaggga agcgcaatcg aacgtcatgc aggcgtccca ggaactgtcc
    34021 gagaagcgta ccgcccatga atccatgagg atgcaggccg cggaacgcga gaggagactg
    34081 ggcgagatgt ccgcgacgga agggcagcag caggataaat tacgtcagct ggacgcccag
    34141 ggcaaggccg ccgccgaaaa ggaatccaag atcaaggtcg agctctccgc gctgaagaag
    34201 atcgaggact ccatgggcag ggagataacc gcgctccggg acgagaagga gaagctgctc
    34261 gggcagaagg gtcaggctca ggccgaccgc gagaaggtca tggtgaagct cgaaacatcc
    34321 aacgacttcc ttatcgggat ggggaccaag cggaccctgg ccgaggagaa gttgaaggag
    34381 atcatgcagg agatcgccca gctcaacctg gaggtaagtt accccttgcc gcctctggac
    34441 gacatccgct cggagatcgt gctctgcgag aactccctca gcggcatggg cgcagtgaac
    34501 ctgcgctcca tagaggatta cgatgagaag aaggccaggc acgtggagct tcgggccgag
    34561 accaagaggc tggaggacca gagggaccaa ttggtcgctc tgaccgacca gttgaacgat
    34621 aagaagaagg tcaacctggt gaaggtgttc gatgcggtca acgccaactt ccgccgggtg
    34681 tacgcggaac tttccggcgg cggagaggcc gaactgcttc tggagaatcc gctggaaccg
    34741 ttccagggcg ggctggtcat caaggcccgg ccgcgcaacg gtaaggtgct gaggctggaa
    34801 gcgctgagcg ggggcgagaa gtcgctcacg gcgttggcct tcatcttcgc cctgcaggag
    34861 tggcagccgt cgcccttcta cctcctggac gaggtggaca tgttcctgga cgccgttaac
    34921 gcggagatgg tggcgaaccg ggttaagaag agcagtactt ccgcgcagtt cgtccagata
    34981 tccttgagaa aggtcaccct gaacaaggcc gaccacatca tcggggtcac caagcccgcg
    35041 gggggcattt ccaacgtcat attcaagccg aacatcggcg acttcagtga gctggagaag
    35101 gagattggtc tgcctgagga aaaggccagg agggatgggg aatgatcgag tcaggaagct
    35161 tggacaacgt gctgggacat ctcatgttcc acaaggcatt gatcgacgag ggacgcggag
    35221 cggagaagat cgaccgctac ctggggctga tgcgctccac cgagggggag aagcagatcg
    35281 ccgggcgcga gccgctcgac cgctccctgc agctggtgtt cgagctggtc ctcagcaacg
    35341 acctggaccc ctgggacgtg gacctaatga agttcgccaa gctctacggt cagaggatgc
    35401 acaccgagga ggtcgatttc atagtcgccg gaaagctcat gcacatggcc tggagcatac
    35461 tgcacatgca gtcccgggaa gtgctctctc tgaacgagag aagggaggag ctgtacttcg
    35521 gggaatggga tacggaatct ttcgaccagt tcgtggagcg ccccctcccc gccatcgacc
    35581 tggacgttcc ggagtgcgtc gagctgacgg aggtcgtgcg ccaccgctgc acccgcgccg
    35641 tttccctagt tgatttgctg gatgcgttcg ataccgccca gcaggaggtg gagatcgctc
    35701 tcaaccggca gcgggtacgc gagcagctcc tcaaggccca ggagaggttc gacggcaaat
    35761 cgcacagcga cgaccaggag aaggatgtgg cggagacgtg ggcgcgtatc gagcgctgcg
    35821 gctccggccc tatcgccctg gaggacctgt tcgaggacga caaggaggac agcatcaagg
    35881 tgttcgtttc gctgctcttc ctggcccgca gcggcaagat atcgctgtgg caggacgagc
    35941 ttccctatgg ccagatatac ctggagataa agctgccctg ggagatcgcc cagctggtgg
    36001 acgggacgca ggccgagacc gtggccatcc aggccaagat ggtgatctga gttggaccgg
    36061 gcggtggagg ccgttctgtt cgccgcgtcc cagcccctgc gggccgcgga catagcggac
    36121 atactcggcg tcggcccgga ggccgtgcgc aaggagatca ggctcctgga caaggagtac
    36181 gaggagcgcg gaacggcgtt cgagatcgcc aagatcgggc agaggtactc gcttcagtta
    36241 cgacaggagt acaatcagta cgcgctaccg ttcgcggacc tggacatgtc ccccgaggtg
    36301 ctgaaggccg cctccataat cgcctacaac cagccgatac tgcagagcga cctggtgaag
    36361 ctactggggt cgggcgtcta cgacaaggtg aggacactgc ggcagatggg gctggtcacc
    36421 ggcaagcatg tcggccaatc gctcttactg agtacgacac gcgagttctc cgagaggttc
    36481 ggactgggga ccaagaagga agagatcaag gagtggatgg aatccaagca gaagcagtag
    36541 gcaaggcata tcccggctgg tccctgaccc gcataccccc caccacttcc acctattggc
    36601 atcttcgtcc caacccggtg tccctggtca gcctgtccaa tgtagaaatg caggaggacc
    36661 tggtgcgctg cgggatggct ctctcgaacg atggctggcc atcggcgctc aagctttgaa
    36721 agggccaatc caggcaaaaa ggtttaaatg caaccgttca atgcctacga gagtgataaa
    36781 atggtaatgc ccctcgcgct catggagaag accttgaaca agaaggtctc gctcctgctt
    36841 aaggacaacc gtgtcctgga aggcaagctc accggttacg acgagtacat gaacatggta
    36901 ctggaagaga ccgaggagcg caccgcggag cagacccgcc gcttaggcat ggtcatactg
    36961 cgcggcaaca acgtcgtgag catcgccccg ctctagaact tttatgaaag ctctgatcct
    37021 ggccgggggc atgggcaccc ggttgaggcc tttaactctc tccacgccca aaccactact
    37081 tccgctttta ggccgtccga tgatcatgca catcatcgac tcccttcccg aggaggtgga
    37141 caccgtcgtt ctggccgtca gctacatgaa ggaccagctg gagacgttct tccgcaagaa
    37201 cgattgcggt cggcgcatcg ttctggtgaa cgaggatgag ccgttaggca ccggcggggc
    37261 gatacgaaac gtgaggcagc atctggacga tactttcttc tgcttcaacg gcgacataat
    37321 cagctcgctg gacctgcgag acctgctttc gttccatagg aggcacggcg gcataggcac
    37381 gctttcgtta tggcaagttc ccgacccatc cgcattcggg gtggtcggtc tggactggga
    37441 taggataatc gatttccagg agaagcccgc ccccgggacg gccatctccg acctcatcaa
    37501 cgccggcgtt tacgtcttcc agcccgagct gctggaccac attccgtccg gggtggtctc
    37561 cctggagagg caggtcttcc ccaagatatt ggacagaagg atgcacggct accgcttcaa
    37621 gggctactgg gtggactgcg ggacgccgga aagctacctg cgggcgcaat cggaactgct
    37681 ggagaacggc cgttccaaga acgcggcctt catgaaagat gccaaattgg tcggcctgaa
    37741 ccatctggac cgggcgaacc tcgacggatg tgtcatcggt ccccacgtct gcgccctgcc
    37801 tggatcgtcc gtggggaagg gttccctggt ggagcgctcg gtgctgatgg aaggcgccac
    37861 cgtaggtagg ggctgcacgg tcaagggctg tcttctaggt cccggggcca aggtcaacga
    37921 tggcgagtca gtacagggca agatactggc ttcccttcag tagtcgtact gacctcttgc
    37981 actaggtata tatcccatca cacttttctc caaacagccc cggggtgaag gtctggcagg
    38041 cagtaaaatg gattccctga taaaggcgat cagccggaag aggttccgta ctggctggac
    38101 cgcgttcatc atcgccttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    38161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnac
    38221 catgatcgcc ctggcgacca tggccaattc cggaggtttt gcaactggcc ctacgttgat
    38281 aggggattgg aagcacgacc tggtcgacaa ctcggacctg gccgcgcctc tggccttcgt
    38341 cagcatactg ttgatattgg tttccctggt gctcttggtg atcattaagc tggtcatcat
    38401 gaaggtgcat ctgcccatgg gaaggatctg gccccgcccg gagaagctgt tctcccgcgg
    38461 ctggttcccc aagaccaagg acggcctggc cgtctttttc ttggtggtat tcgtcctgat
    38521 accgtccttc ttcatcttca cctatgtggg ttctgtggag tcctcctcct tcgactgggg
    38581 tccgttcacc gagagcctcc tgttctcctt cctggtggcc ggggtggtga cggtgatcga
    38641 catcgctctc ggtgtgcccc tggcattgta catagccaag aaccggaccg gcaagttatc
    38701 ggaggttctg gacgttctgg tgaacgtacc tttgatcgtt cccaccgccg ctctcggcta
    38761 ttcgttgggc gtattctgga ccgggcagaa cataattccc acctatgacg ttctgctgat
    38821 catcctggct cacgtggcct tcacatatcc actggtcgtt cgtaacgtag ccggagcggt
    38881 ggaggaggtg gaccccgcct tcgaggagac ggcgcgaacg cttggcgcta aaccggtgca
    38941 ggccttccgt cgcgttctat atccaataat caagagctcc atactggccg gggctatcat
    39001 ggccttcacc cgcagcctcg gtgagaccgg ggcgaccctg gcggtagtgg ccaaagccaa
    39061 tacggcgcca gtgttcatcg ttaacttgat aaacgaaaag accgcctccg gctactacac
    39121 cgccgggctg gcctgcatag ttctgataat agtgtccttc atgttcatgc tggccctccg
    39181 ctacataacc aaccggaggg cacactgatg ccagacgtga agctggtcgg cctcaggaag
    39241 tcctacgggg acatcaaggc cgccgacggt ctggacctgg aggtcaagga cggtgagtac
    39301 ctctgcgtgc tgggaccgac cggcgccggt aagactacct tgttgcgcat gatctccggc
    39361 ctgctggtgc ccgacaaggg caagatattc ttcgatggcc aggatttcac caggatggag
    39421 atcgaggagc gcaaggcggc cctgctctct cagacctacg cgctgttccc tcagctgacg
    39481 gtggaggaga acataacgtt cggattggac atccgagggg cggacgagaa gctgaaggag
    39541 caggtgctca tcagcatgct agacctggta cggttatcag gacgttcgga cgcttacccg
    39601 cgggagctga gcggggggat gcaacagcgt accgcgttgg cgcgtgccct ggcgtccgga
    39661 gccgacctgc tcctgctgga cgaaccgttg cgggctttgg acgcccggct gcgcatctcg
    39721 cttcgaaccg agctacgctc gctcgttaaa acgctcaaga tgaccgccat acacgtgacg
    39781 cacgatcagg acgaggcgct ggtcatggcc gaccgggtgg cggttatccg ggaaggtcgc
    39841 atattgcaga taggaacgcc caaggaggtg tgggacgaac cggccacgcc cttcgtggcc
    39901 aacttcgtcg gtcagtccaa cttcttcacc ggggaggtgc tgcagtccag tcctttcacg
    39961 ctgatacgaa ctccggaggg cacggtgctc aagggccgcc cgtccgagct ggcgaccgga
    40021 accaccgccg tgctcggcgt caagataggc aacaccgaca tatcgaagga aaggaaaggt
    40081 taccttaagg caaaggtgga gcgcataatc ttcgaggggc gcaacctaca cgtggatctg
    40141 atgatggaca acggtcagcg gatctcctcc aaggtcccct cctggcgcaa aggcaagata
    40201 gcgcccgggg acgtagtgga cgtctactgg gaagagtcca aaggcacggt gttccccatg
    40261 ccgccgaacg gcctggagaa cgaactgaag gtggaatgat ggtcgaggta aggctggaag
    40321 gggtgggcaa gcgttacggc tccgtggtcg ccgtggacaa ggtcgacctc accgtcgccg
    40381 acaaggagta cgtgaccgtg ctcggnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    40441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    40501 nnnnnatgct gcccggcgag ctgtgcggcg gggagcagca gaaggtgtct ctggccagag
    40561 ctttatcctc cggttccaag ctattgttgt tggacgaacc gttgtccgcc ctggactccc
    40621 gggtcagggt ggacctgagg tacgagctgc gccgcttggc gaaggagctg ggattgacga
    40681 ccatccatgt cacccacgac caggaggagg cgcaatcagt atccgaccgc atcgtgctga
    40741 tgcgcgccgg taccgtggtg gagacgggaa cgcccgagga gctgtacacc catccgaaga
    40801 agatattcac cgccaacttc atcggcgaga cgaacctgct ggaaggctgg gtgctggaaa
    40861 tcaaggacgg ggtctcggtg atcgagctta ggaacggcgg gaaggtcaag gtgaaccagg
    40921 cgaaccaccc ggtgggagac gccgtggtca tctccgtccg tccggagttc gtgttccaag
    40981 cggacgaggg catgagggcc aaggttaccg ccatcactta tatgggaacg tactggcgca
    41041 tcacggccaa cactgaggat gaagaggagg tggcctttga ttcggtcacc tatgacgaaa
    41101 accttttaac catcgggagg gaagtgtatc tagcggtcaa tcccaaggcc gcggtgctct
    41161 accccagacc ggaagacgga gtacaagagg cgattaagct tgagtgagag aacatcgttg
    41221 ctggaatggt tctattcgcg ccgagaatcg gtggtatcca aggacatgcg cgggcatgcc
    41281 caggacgtgg gagacaccat aatcgagttc aaccgggcca tgggaatgct gtgccgcggg
    41341 gagaaggagc aggccctgga cgcgctgaaa cgctccttcc tggccgagaa ggccgccgac
    41401 gcccgcgaga tatccctgac cgaggggctc tcccgcgggg acctggagga gaagaaccgg
    41461 gaggacctgt tacatctggt ccgccgcatg gactacgccg ccgactggtg caaggaggcc
    41521 gggatgaacc tgcagctggt gctggaactc aacatcccga tccccttgga catctggaag
    41581 aagttcaaca ccatgaccct ggagctggag aagatggcca aggcgctgaa ggtatgcgtg
    41641 gacaacctgg gcctgaacaa cgacctggtg ctgcgcaccc acaaggagat agaggaatcc
    41701 gagcacgcca tggacgacat gtacttcctg atgaagaagg agttcttcct gaccaatctg
    41761 gacgcccgag cgatctacct gatgcgcgac ctgctgcacg gcgtcgagaa ctccgccgac
    41821 aatttcaagg actccgccga catcatccac attctgatag tggcccagcg ggaccgcccc
    41881 aggtgatgtg atgaccaaac tgttcggcac caacggagta cgcggagtga tcaaccagga
    41941 catgagcgtc gagctggcgt tggacgtcgg acgggccata ggcactttca tgcagggcaa
    42001 ggtggccata gccacggact ctcgcacctc ggccgatatg atccgggcgc tggtgtccgg
    42061 agggatgacc tccgccggct cggacgtggt ggacctgggg atgcttccca cgcccgccct
    42121 tcaatattac gttaaaaatt ccggggtcaa gggaggggtg atgataaccg cctcccacaa
    42181 tcctccagag ttcaacggca tcaagtgcgt cgaccacgac gggaccgaga tgcccagaaa
    42241 gaaggaggag gtcatcgagc ggatatacgg tgacagagag ttcgccaccc cttcctggaa
    42301 ggacgtgggt aacataactc acctggcggg cgtgggggct tcctacgcca acgccataag
    42361 ccgcgcggtg gaccgcttca agatcgggga ggccaagctg aacgtcgttc tcgattgcgc
    42421 gaacggggcc ggcgccgtca cctcccccgg tttgctagat actttgggag tgcgcgccat
    42481 aaccctgaac gggaatccgc agggaacctt ccccgggcat ccgagcgagc ccacgccgga
    42541 caacctcagg gacctggtgg cagttgtcaa agccaccggc gccgatctcg gtatagctca
    42601 cgacggcgac gcggaccgca ccatattcgt tgacgaccag ggcaactacg tctacggcga
    42661 tcaatccctg tcggtggtgg cctcccacat ggtccaggag aaccagggcg gcatcgtggt
    42721 caccccggtc agcacctctt cctgtctgga agaggtggtc aagaagcaca acggccaggt
    42781 catatacacc aaggtcggcg ctcctatagt cgccaggcgc atgatggaag tccaagcggt
    42841 cttcggcggc gaggagaacg gcggtctgat cttcccggag caccagtact gccgggacgc
    42901 cgccatgacc atggccaaga tgctggagat aatcgccatc aagggaccgc tgtccgaact
    42961 gctcaaggag gtgccccgtt actgcctgga caagagaaag ctctcctgcc cggaggacaa
    43021 gaaggaatgg gtgatggagc aggtcgaggc ctacttcgcc gatcagcgca cggacgccac
    43081 cgatgggatc aagatattct tcgagggcgg ctggagcctg gtccgtccgt caggaaccga
    43141 accgatattc cgcatctact cggaaggcaa ggacgagggg accgcgaaac gttgcggtga
    43201 ccagtgcgag aaagtggtac gccagctgct cgaggaatga tcagaggaac tgctgggcca
    43261 ggaatattat tccgaacacg atgaagacga ccccgctccc gatgcggatg tagttcttgg
    43321 ggaccttttc cccgatggcc tttcccaacg agacctccag caccaccagc cacaggaagc
    43381 cgagggaggc gccgatgaac accatgaggg ccgatccgga ttcggcggag agcgtgatca
    43441 cggacaattg cgtcttgtcg cccagttcca tgagcgccac gaagccgaag gccgccacga
    43501 accctcccca gcggcccttg tccttcacct cctcttcctc ctcctcttcc ttgcggacca
    43561 gggtgactat gccgaagatg atgaagacca ccccggcggc cagtccaacg atccaggacg
    43621 gtacgaactg aaagagcacc tcgccgatga ccacgccaac ggcggtcacc gccaccaagg
    43681 ccaggaagga accgaggaac accgtgcgct tggggtactt tgaggatagc gtgatcacgg
    43741 cgatcatggt cttgtcgccc agctcggtca gcgaaatcag aatgaaagcg gagatgagcg
    43801 gggcgaggtc catcacatct ctccccgtct ggtgtgcacg atcgccacca cctccatgat
    43861 catgcgggcg gccaaagccg ccgtggtccc gggatcatgc gacgggagga cctccgagat
    43921 atcgaaaccg accaggcggt ctccgagcat atcgatgcag cgcttcactt cgtaaccggt
    43981 caggccgaac ggttccggac gggaggttcc cggggcgaag ccgggatcga tgccgtccat
    44041 gtccaagctc aggagcacgt gctcccggcg catcatgttc aggaccttct tccaggagtt
    44101 cacgacgcct ccctcctgga tctggtaggc gtccacgtaa ttgggcatct cctgcccgat
    44161 ctcccgcttg gatatggaac ggacgccgaa gggaaccacg ttctctatgc ctacgacgtc
    44221 ggccaccttg cgcatggtgc aggcatgatc gaacttacgg tcactctgca attcgaagtc
    44281 caggtgcgcg tcgatggaga tgacgcccac ttcctggtaa gccttgacga atgggtaggt
    44341 gatgctgcgc tccccgccca tgatgatcgg gaacttgccg gccttgacga ccttggtggc
    44401 ttccttctcc acggccttga acatgtcctc gcaggacgag ccgcaatcca ggtcgccggc
    44461 gtcatggacc tttaccgtcg atacgtccag gtcgtgctcg aaaaggtaag gatcgaaaag
    44521 acgggacgcc ttacggatgg cggtaggcgc tttacgagtg ccagagcgga aacgggtggt
    44581 cccgtcgtac ggaacaccca aaatgacgaa ctccgcctcc tcgaaggtgg aattggccag
    44641 ggcgaacgag tcgctgcggg ccatgatcgc tcggagcgga tcacaccttg gtgatcttgc
    44701 ggcggtccat ggctatcatg tacatgatat cctcgcccgc ggtcagctgc cccttgtact
    44761 cctcgggtat gggcaactgg aacgtctcgt agttgtccag gtccatgagc tgcacctcct
    44821 cgccggagat ggacaggatc tgggccttgc gcttgtcgat catcggtacc tgcaccctgt
    44881 gcttgaccgg gtaaacgaca ttgcgcttgc gaccatcgaa tatgcctacc gcgtcgatgt
    44941 tggccttcgc ttctccatgc ttacctggct tggaggtggc tatgttgatg atcttgcagg
    45001 gctcctcgtc gatgagcata tatctgcctt ccttgagctc cctgacttcc tgttgggtcc
    45061 acgacataac aacctctgga gggaattgac ggtacgttta tataatttct tatcgccggt
    45121 gattctggta atatttaggg ctggggcctt tccgctgctg cggtctaacc tgctggctct
    45181 gctgtcgctg ctcccggcga ggtggctcag gatacttctc cttgatctcg gcgacccgct
    45241 tctccatctg ttccttcagc ttatcggcta tgaactcccc gcggtaggcg tccaccttgg
    45301 cggcgatgct gatctttccg ccgaggcttc gagcgacctt cccccgctgc cagtatggcg
    45361 agcggttgat ccagggatgt tggaatatga ccccgtgctt gggaggcctc tttccggtgc
    45421 gcaggtgcag gaacaaggcc ttctccgccc ccaggagctg aaccgtggac gatgggaact
    45481 tcgccaggcg ctgcagccct ccggccaagg atatcagtct ggccgccagg ttcggattga
    45541 gcagcgccga caggttgggg gccacccggt ccatgccctc caggacgtag gcgtccaggg
    45601 attccttccg gttgtacagc tcgagaagcg tccttcccat gccgcgtatg atgtccaggt
    45661 ccctctcgac caggtccgtt ccgaccgatt cgagggagac gcccaagtgg tccatgatga
    45721 cctgccggtc ccccatctcc gagacgagcc gggcgtactc cgcgtccacc gcgaaatctc
    45781 ccagctccgg gaagtacacc ccgtaccact cgtgcaacct ttcgctgagc aggttgatct
    45841 cctctatcag atcgtccgtg gcccggatgg cctgggcgat ggagcggtcc tcgctgagcg
    45901 gctcccgcac ccggatctta ccgagctcca gcatgacctt ctgcatcatg tccggagtta
    45961 ggccgtagtt ctcaggcctg atgaacgagg aatcgaagac cataggtttg ccgagcggtt
    46021 tcaggcgggc gtcggccacc ttcatcctct tgaccgccag agccttctcc tccgggagta
    46081 tctctccccg ttggacggcc gccagcttct gagctaccag cttgggctcc ttatcgaaca
    46141 gcttgaaccc gcggacctcc tggccctcgc acaggaacac tccgaaccat ttggtgacaa
    46201 gtatcattgg atcacttcct cagtatgcgc cggacctcat cctccggcaa cggtctgcct
    46261 ttcctcagca acgccagccg gtactgcagc tcggcgtgcg cctccagggt ctccatcctn
    46321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    46381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt ttcggtagac ggtcaggtga
    46441 aagggcgtct ccatggacgg tcttccgctg accgcctttc cggagacgat atcgaccgtc
    46501 accagctcgt tctggtccag catgcccttg cacgatccgg agggcgtgat gaccatcata
    46561 tcgccgaccc gagcgctgat gttgcccccg gtcccgttgg tcagcccctt ctcgtacagc
    46621 agccttccgt aacgaacgac gtccatgcct gcctgcttca cagtctcgcc cccttcattc
    46681 tcctgacgac gtcctgaggt ctcattaccc cgttctcggt gattatcccg gtgaggtatt
    46741 tggccggggt gacgtcgaag ccggggttca gcgctttgca gccatgcggc gcgatgcgca
    46801 cgccgtccac gacggtaact tcctcctctc cccggtactc gatcggtatg tcctccccgc
    46861 gcttgatgcc caggtcgaac gtggacagcg gggcggcggt gtagaacgga accttcagct
    46921 ccttggccag cacggccttc tcgaacgtcc cgatcttgtt ggcgaaatcg ccgttggcgg
    46981 cgatgcggtc cgcccccacg atgaccatgt ccactccttc ccggaggaaa tggccggacg
    47041 ccccgtccgg tattatcgca tgcggtatgc cctcgttcag cagttcgaac gcggtgagct
    47101 tcatgccctg cagcctcggt cgcgtttcgg aaacgtagac gaatatcttc ttgccgttgc
    47161 gccaggccgc ccttatcggt gctaacgccg taccccagtc cacggtggcc aaagccccgg
    47221 cgttgcaatg ggtcatgatg cggtcgccat ccttgatcag cttctcgcca tgctccccga
    47281 tcaggcggca ccgttccacg atggtctcgg cgtactcctc ggcagagtcg gtcggatcgt
    47341 cgccgtcccg tatgcgggac agcatgtggt ccaccgcgaa gaacagatcg aaggccgtgg
    47401 gccgggtgcc cttcagctcc ctggacgcct tatcaaggtc ctcgtgatta ttggcggcca
    47461 gcatcattcc gtaggcggcg gcgacgccga tggccggagc tccgcgtacg gtcatgtcct
    47521 tgatggcctc ggccacctgg tgatggtcct tgaaccccag aacctcgacg cggtgcggaa
    47581 gtatcctctg gtccaacatt cggacgatcc catcttcgca ccagatcgcc cgcatctcgc
    47641 tgaccttgcc gtccatcctt atcttcatct gctctcgttc acgggagggt cagcaatcta
    47701 attaagttat gccggaggcg atagttcgta actttacgat agatttaact agagagagcc
    47761 ataatcagtg tccaggcgat tactctgtcc agcaggaaca cggattttga tgtttattcc
    47821 actaccaccg gacttagaca gatctccaat ccggtacgcc agaagatcct gagcgagctg
    47881 cagaggcggg atctcagtct ttccgagatc gcggtcctga ccagcaaggc gcagagcacc
    47941 ttgtcggtgc atctggacaa gatggtcaag gagggcctca tcggatatcg ggacgatccg
    48001 caggacaatc gccgtaagat attctacgtg atatctcgcc cggtgggcag ttcggtcgtt
    48061 ccccgagagg agctcaagaa ggcggtagcc aacaccatcg gaaggaccat cggaacgccc
    48121 agcaccttcc tgaagggaac catccgttcc atcgtcatcg gcatggaggc cataggcttc
    48181 aacatggacc cggtgctcaa ggacatcggc cggcagatgg gggcagagat atccacccgc
    48241 atgaaggcca acgacgtgga agggctgatc aaggaggtca aggatttcta cctcgcgcac
    48301 gagctgggcg aactggtggt cttctcgctg cacccggtga ccctgatcat acgcgacgag
    48361 tacgattgct ccaaggcccc tgacgtcggc aagacgctgt gccttctgaa cgagggtata
    48421 ctggaatcga tattcgaagc caggctgcat atgcccctgc gcgtggtgga gaaggatacc
    48481 ttcggtacga acttcaacat gtgcaagtac gtcatcgagc cgtccctctg agcgggacgc
    48541 tcacctcttt cctttcctta tcacttcgta cttcagccag accagcccgt tctccagttc
    48601 ctctacatgt ccgagcttca gctggcaggg cttgggcagt tcggctacgg acggatctat
    48661 gaattgagcg ctgttctggt tccccactac gcacgggctg aggatgacgc tgatctcgtc
    48721 gaccaggccc tccttgagca tgatggccga tagcgttccg ccgctgtcga tacgcaaagt
    48781 tcgcaatccg tacctggact ggagctcctt cagcgccttc ttgaggtcca cgtggtcctt
    48841 accggcgatg atgatgtcga tcccttcccc tttcagatac tgcaggtact cctcgggcgt
    48901 tgagcgggag cagagcgcca ccggcgtctt ccagaagggc tgcctcttga tggcgctcca
    48961 gttgcgcacc cgtcccttgc tgtccacgat ggccatcacg gagcgggagc agctgggaaa
    49021 gttcttggct gcctcatagg accattccgg aacctcgtcc gggatcggtg ccgccaggaa
    49081 ggtatccgcc ccggagatcg ttccgtctgg ttcgaacgtt tccgccagct gataatgagc
    49141 gcccatgtcg atctcgaaac cggtgactcg ggcgtccagg ctggtctgga tgtgcagaac
    49201 gactcgcagg tccttcatga aaaacgattg cccacgatcg tataataatg tgatatttgg
    49261 aagattaaaa atgaggtggt tagaaagatt ctggtgggct catccggatt tgaaccggag
    49321 accttctccg tgtcagggag acgtcataac cgctagacca tgagcccttg gaattggccg
    49381 taagttgttc taattgatat gcctttcgtc gtccacttcc cccagatcca tagtctggtg
    49441 tcatggttcc acgggcaaat ttttattact tgctccctct tgcatccgat gagctaaatg
    49501 acggagatat tacttttcac caaacctgac tgccaaaagt gcgaatacgt caagtcccac
    49561 ctcccggaag gcgtgagccc gcgcatcgtg gacacctcga tcgctgatgg actggccgag
    49621 gccgcttact acgagatatt gcacaagaac ctacccatcc tggtggtgga cgatgaggtn
    49681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    49741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna ggtccgggct gaagttcaag
    49801 gacatcggcc tggtgtgctt ctccaaaggt cccgggctag gaccttgctt gcgtaccgtg
    49861 gccaccggtg cccgtgctct atcgctatct ctcaacgtcc ccatcgtggg cgtgaaccac
    49921 tgcatctccc acctggagat cggcaggatc aagaccgagg cccaggaccc cgtactgctc
    49981 tacgcgtccg gaggcaacac ccaggtgatc gccttcgcca acggtcgcta ccgaatattc
    50041 ggcgagaccc tggacatagg catcggcaac atgctggaca agctagggcg ggagatcggt
    50101 ctgggctact acgccggccc caagatcgag aaggccgccg cccagggcag caagctgctg
    50161 gaactgcctt actccgtcaa aggaatggac atggccttct ccggcatcct caccgccgcc
    50221 gtcgctcacc gcaacaaggg cgagagcctg gaggacatct gcttcagcgt gcaggagacc
    50281 tgcttcgcca tgctcacgga agtgacggaa agggccatgg cccacgtgga gaaggaagag
    50341 gtgcttctag gcggtggggt cgttcagaac aagcggctgc agcgcatggt gctggacatg
    50401 gcggaggcgc gcggcgcccg aatgtacgtg cccgaccgga cgctatgtat ggacaatggg
    50461 gcgatgatcg cctggaccgg cctggtgatg cataacgccg gtatcgttca ttccatggaa
    50521 actaccacca tcgaccagcg cttccgcacc gatcaggtcg aggtcacttg gcgctgaccc
    50581 ggttcatctg ttttgatatt atggcgtcaa gcgcctgaat gaagtcgatg tccttgccca
    50641 gcggtatgct ggctccgctg gcgatattat gaccaccgcc gaccccgccc acggaggcgg
    50701 cggcgtccct catggccacg gacaggtcca ggccatcctt gtccaccaac ttcctcgttc
    50761 cgcgggagga caccttgaac tccttgtcca ttctggtcaa gcagatagta gccttgtcct
    50821 ggtcgccgat ccattgcatg accaagccgc acagttcgct tgacacttcc cgttgctggg
    50881 attcgaagtg ctgtatggcg atctccttgg agaccccgcg ctcggccgtg cgcttcgccg
    50941 cgttcaggag catctcgtca tactccttga gcaaagaatc ggcgcgctcc cgagattcct
    51001 tctccccgag gagcatggat agccccagcg ccgtttcgtc aacccgcccg caagcgttta
    51061 tcaatctggt caactggtag gcccgggagt tgtcctgggg aaagaagtaa tcgggagcca
    51121 gttcatcttc cagactgccc agtgagcagc cctgctccag caggcgcagg gagatcaggg
    51181 acgagagccg tctctttccg ccctcatcca atccgtccca ggtgctctcc ggacggacgt
    51241 tcgcctcctg caacagtctg gttatgccct gggcgtcgcc gctcacccct ctgatgaagg
    51301 gatgggaggt tctcatgaga ccctcgccga tcggtcccgg gggaagcaac gaacccttct
    51361 tctcctgcac caggttccgc ttgctcccct cgttgaagag gtgggcgttc accccgctca
    51421 acccctgcat gtgctggcgg tcgccgacca tcccggcgaa ggagagcggt agaaggtccc
    51481 agttcccctc ttcgaccgtg accgccaaga gcatggcgag cgtgctggcg caggcgtacc
    51541 tggctccgtc cactttgagg actgccgggt tgaggtgcat gaccttatcc gaatccttct
    51601 ccggtcggtg gtggtcgagc acgatgacct tgacgcccaa ggattccagg gcggtgaggt
    51661 tgctcgagcc catatcggcc acgatgagca gatcgacgcc cttgaccagg ctggcctgga
    51721 tggccgggag gtcgaagctc ttgagcatgg tggtctggga accctttccc gcccggacca
    51781 gcatggacgt cagaacgctg gcggcaccta tgccgtcggc gtcgttatgt gaaaagaccc
    51841 gggcctcggt gcattcgcgc accgcggccg cggctaagga aaatcgaagt aagaggtttt
    51901 ccgggaggac gctggcgtcc atatcctact cactcaatga gcagctcggc gttcttcagg
    51961 gaatagttcc agtcagcggg aaggatgtcc ctgttcttgt agtacttgac caatcgcctg
    52021 atcttggact ccactagctg aagtccgcgg cggttggaat ggtctccgcg gttgccgttc
    52081 tgtacgtgca agttgaggtt aatggccttc ctcatcaatg ccatcaggtc ctccgggagc
    52141 ttgggggtca gaccgttctc gttcattatc tccagtacgg tcttgccggt ggccagctta
    52201 acgctgggta cggcgtgctg gtccctcagg accaggccga tcttggagct ggtcatgcct
    52261 tccttaccta gcttgaccac catctgtact acctcttcgt ttgacagcgg gacccactcg
    52321 gggttctcgg tcagcagggg cctcctggaa cgggaagaac cccttctcct ggcgtgcatt
    52381 cttgccatgt gaacatcatc ctatatcgtt attgtaaatc atttacttcg taggtggcgg
    52441 cgaagtgacc gtctatttca ctcttactat ttaagagtta gagcctttcc cagcttgttc
    52501 cgcacggcct ccctggccca ggcgatctgc tcccggtact cgcattccgg gaaggccagg
    52561 ttctgcggta gctcgttcat cagctcccag cccatctccc cctcccccac ttccttgccg
    52621 agcactccgg cgaacaccac caccggcccc atcggccggc agtccaggac ctccagatcg
    52681 aagccgcact cctcgcggta ctctcgtttt atgccgtcca gaggggtctc gaactcctcc
    52741 agcttgccgc cgggcatctc ccatcctact cgcttgggat tgtagaccat gagaaagcgg
    52801 tccccctgaa aaccgatggc gtagacgttg ggcagacggg tcacctcttc atttgaaaca
    52861 ttatcataga tgggctgacc ctatttatcc gattcccgtc cggcggagcc cctgcttgga
    52921 gtggaggcta agaagctctt tccaccacga tcatggcgtg gtccttctcg aaaggttcta
    52981 gatccacgat ctcgacaact ttgaacccct ccttcctaag gtagttggcg gcgtcctgga
    53041 acacatcccg cggttctcgg gtcacgtcct ccgagcgcgc tttgacggcc agcattccgt
    53101 acggtgcgga gaaacgcttc atggccttgg cgaacatcgc cgcctgattc ttctgcgcca
    53161 cgtcctgata gaccacgtcg gccttctcga ccaggaacgc caggtcgtcc ggcttggtgg
    53221 cgtcgccgag tatcggcatc atgttcggcc tttcctcgca gacgcccacc agatcgcgga
    53281 acatgcgcgg agatatctcc accgcataga cccggccttc cggagcgagg tccgagacgt
    53341 ggctaggggt ggtcccgctc gaggcgccca ggtatagcac gtgggaatcc ggtttgaatg
    53401 ggaacgagga accgcccttg cggatgaacg cgccaagctt gctgcggtcc ggggaccatt
    53461 cccgatactc ctcatcctcc tgggagaaca ggcgttcgcc gtagacgcgc ttgcccgggg
    53521 cgaggttctt ggtcaagacc atgtctccgg aacggtatac tccagggaaa cttgtcggct
    53581 cgatacggaa cttggcctcg cccatgtccc tgccatgacc gacagaatat taagcgtttc
    53641 accgacatca attccttgtg gcgggagagg aggaggccaa acgcatacag gagctcactg
    53701 agcgcatcgc tcagctggag gaggccatcc gccaggtctc cgtgccgtat gggcagctgg
    53761 cagcccagtt ggccaccttc caggacacgg tggggaagta ctttcggctg atggacctct
    53821 accagcgtta cggcgtggtg tccgtcgata ccatcctgcc ggaggtgaag gaccccatct
    53881 ccaaggacat attgcgcata ttgctggacc accccgatct gaacatctcg cagctcaccg
    53941 atgagctgaa gggcaggagg ggcagctcgt ccaggcgcat cgtgcgggag aagctcaacg
    54001 agctggcgga gatgaagctg gtggtcgagg agacggggcg gaacgagaga tcgtaccgcc
    54061 tctccgagga cgtggtgaag aggtggtcac aggtgctcgg tctgaccaag tagggtgacc
    54121 actcataggt ggaggcatgg gaacatgggc gacgcgggac aagaatgccg aggcgcaggt
    54181 gcgaataacg atgatgatga ggtgaagtga tgagcgacaa cgatatgccg gacccggaac
    54241 agttgagaca gatgttcacc gtgctcaccg agcaggtgcc gccgctcctg gatagcatca
    54301 ccaaggtgct gtacggggcg caggagggta ccaagttcgg ggagtccgtg gccgccttct
    54361 acaaggcgct gcgggacgcg gggatgagca acgagcaagc cttcgagctg accaaggact
    54421 acatgtccaa tctcagcctg ggcgggatgc tcaagaacat agtcagcggg gcctccaagg
    54481 accacgattg aggatgggga tgcctagaac agagaagcaa aagaaagatg gccaggcgat
    54541 catttacatc gccgcggccg ttcccgggct gctcatcagc ctggggatcg cctacctgcg
    54601 catgcgcaaa cgcgccaaaa aggaggcgcg ccggttcttc ctgaccttgg tacgggacgg
    54661 cgttccggtc ccgcaggcca aggaattggc cgacatctac gcctccagca tctccctgac
    54721 cgagatgatc agggagatgg gcccgttcac ttcctgaaca ggtactcggc gataccgtag
    54781 ccggcgtcct cgccgtcgtc gatgcgccac ttggtcaagg tctcgaacat aatggagccg
    54841 cggtcgttct cgcccttgaa ctccatgatg gccttcttct tgacctcgcc cttcacaccg
    54901 tagacgacgc cgtccttgtc gtacatggcc atgtatagcg tgttcgggct gccgtccgca
    54961 tcgtactcgg tgaccatgtc caccttcacc aggggaaggt tctccccgtc cacgtacagg
    55021 aatccggcgt cgatgtcgcc cttgtccatg tacagcttgg tgacgttgaa gccgaagtcc
    55081 tcgctgacct ggcaggtgag ccacacccaa gcgcgcggag cggtccagtc cctctcgccc
    55141 caggagtggt ccctctcgcc cagtcccttg atgtagtagt cccggtcgtc gaccttcagg
    55201 cttcccagga ccttgcccat ctgctccagg tgctcggagg ccacggacgc ggccaaggct
    55261 tccttgtccg cggtgacgca ctcgcgatag ttgaacatcg ggttggtccc ttcgaagcgc
    55321 aggtcgaact tgaccttggc cacggtgtcc tcgcccttct tgtgggccgg aagctcgccg
    55381 tcgaacgtca agttccagac cttctcgtcc tccaccttgg tgaaagtgag gcctttggcg
    55441 ttcaaggtcg ccccgtcgaa ctccaccgtg tccttggttc ccaccaagga tccgtcaggc
    55501 atcatgaaga agcagaatag catcttctcg ttcttgttag gtttcaggcc taggcgcatg
    55561 aatccgcaga tgtcgttgcc gcggtcatag aagctgaagt agaaactttc gttccagttc
    55621 ttctgctcgc cctgctcgtg aataatgtcg gtttccactg gaatcatcct tccctgatgt
    55681 agatcaggcc ttcgttgccg tcaagggtta tcctctgacc cgttatgaag attttcgttg
    55741 ctcccttcac cgcggtcacc gccgggatgc cgtactcccg ggacaccacc gccccgtgcg
    55801 atagtatgcc gccagtctct gtgatcaggc cggcgatctt ggagaagacg gccgtccaac
    55861 ccggatcggt gttggaggtg accaggatct ccccctcccg gatctcggag agctgctcta
    55921 tggaatcgac cacccgcacc ggtccggtgg ccacccccgg gctggcggac gtgccggtga
    55981 gctgcgcgga gttctccacc atcttcacgg tgtcgtcgaa ctccaccacg cccttgagga
    56041 acttcggcgg cagctcgccc ttccaatcca cgaactcctt gcggcgttcg ggtatcttgg
    56101 tcagggcctc cttcccctct cccttcgcca gggcgaatat ctcatccttg gaaaggaaga
    56161 atatgtcttc ctgcttggcg atgatgccct tctcgaggaa acggcgggcg aactccatat
    56221 acacccggcg ctgccgatag agtatgtggt ccaggtagta gcgttggttc tcccggaaca
    56281 tcagataggt ctgggcgaag cccatgaccg tcttgaacat ccgggccttg agccatcccc
    56341 gttttatttt gcgtatcttg cccaggatct ccttctccac ctcctccctt tcccttatct
    56401 tccgtctctc cagctcttcc aggtccaccg ggggtgacga ggccagcgag cggacgatat
    56461 cggctaccag tcggggatcc tcgccccagc gggggaagta cacctcgcgg gtgtgggagc
    56521 ggtgtccgta ctgcttcagg aacgaatcga actccttggc gtagttcgac atcttctcat
    56581 cggagcgcat ctggaccagg acctcggcgg agctcagtcc cagcaccttg cccagtacgt
    56641 gcgggtcgga gcgggcggcg ttagccaggt ggttcagggc gatgttggtc tcgatggtct
    56701 tgttgccctt cagcccgctg atgaccctgg aatagaggac gcccttgtca tcccctatcc
    56761 agtcctgaag ccagcgcttc atgatcatgt tcatgccgat ggagtgcccg accatcccgt
    56821 agcggataag ccggtaatgc ttgatcagct ccttctccat ctcccagacc acgtcctcca
    56881 gcttgtcgtc cggtatcgtc gtgagatcgc ggacgtcgaa ctcctccgcc cacctcatga
    56941 accgccgggc ccagcgcttg tacgccttgt cggtgcgcag gatgttcccg tcccaatcaa
    57001 ggacggtcgt gcgcagcatg gccaacaccc tcttgccggt gcggaactcg gcgttggcga
    57061 tgcgctgctg gtccctctcc gggaagtagt tcagaaggtc cttggtgcgg gagaacttgg
    57121 gattgtacat cagcatgccc tccagcacct cggcgttgaa gtagacgtga cctttatgga
    57181 tcttgagcag cggcttgttg gtgagctcct tgtagcccat tatcgcgctg ccctcccagt
    57241 tgacgtactc ggtcagccac ggtcccagca gggagaagaa cagcggcgac gtgacgtccg
    57301 cccagtactc atctccataa ccgcgagtcc acagggtgag gtccccgccg atggtggtga
    57361 tgggccggga ctgcaggagg tatatcttgt ccccctccgc cgcccattcg atgtcctggg
    57421 gggatcccat atgtttgtgc aattggatgc ccagcttggc caccagttcc accttccccc
    57481 tggtcagcga cggccggttg cgctccgatt ccggaacgtc caccaccttc tccccctccg
    57541 gggaaaggaa tatcgcctgg gccttgctgt tgatcttgga ctccttgacc tccccggtgc
    57601 tggagtcgca gacgaagcgg tccggcgtaa cgaggccgga ggctatggac tcgcccaacc
    57661 cccagctgga ctcgatgacg atcttctcat ccccggttat ggggtcggag gtgaacatta
    57721 tccccgagga atcggcgttc accatgcgct gcacgaccac cgccatgccg gcgtccaggt
    57781 ggctcacgcc cttgtcgtgg cggtactcta tcgcccggtc gttccagtag gaggcccagc
    57841 acttcttcac gctctccgcc aacctttccc tggttacgtt aaggtaagtg tcctgctgac
    57901 cagcgaagga ggcctgttcc gtatcttccg cgatggccga ggagcgcacc gcccacagtc
    57961 cggacggacc gaaggtctcg gtcctatcaa acagctgccc agccagcatg ggatcaagtt
    58021 ctccggccat catccagccg cgtatgctct cggcgcagcg gaccaccttc accgcgtcct
    58081 ggtggtccag gtccttgagc gcctccgaga tgcgctgccg caggccgttg cggtccagga
    58141 actgctcgta tgcggaagta ctgaccaccc atccctcggg cactgggaac ccggcggcca
    58201 gcaggtccat caggttgcgg gccttcccgc cgatctcttc gatatctccc ttcgccgaca
    58261 acgagatgac ttgctctccc aaaagatccc tctgccacgt ggggcgataa gggaatgaca
    58321 tgttctgtat aaaccgtttc catggttctc actggcgcaa ttatgaataa ccccccgtca
    58381 atatccaggg ggatgaggga aactttggaa tggctggccg ccgaggtggc cggcaggatc
    58441 gaccaggaat gcgccttcag cgaccgggcc gccgaggtgg gcatgggggc tgacggtacg
    58501 ccgacatgcc tcatcgacca gatcgccgag gacctgctct tggaacttat ggacaagagg
    58561 aatgttccct tgaacgtcct gagcgaggag gcgggtttca ttgaccgcgg tcacgagcgc
    58621 acattggtca tggaccctgt ggacggtacg tacaactccc tgatgggaat tccgttctac
    58681 agcgtctccc tggccgtctg caccaagagc atgaacgacg ccacccacgg catagtg
//
LOCUS       DAOPZI010000004        49180 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_570_length_49180_cov_9.550107, whole genome shotgun sequence.
ACCESSION   DAOPZI010000004 DAOPZI010000000
VERSION     DAOPZI010000004.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 49180)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 49180)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49180
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_570_length_49180_cov_9.550107"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(5..1321)
                     /locus_tag="PKM11_01875"
     CDS             complement(5..1321)
                     /locus_tag="PKM11_01875"
                     /inference="COORDINATES: protein motif:HMM:NF039904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HNX47293.1"
                     /translation="MSSQKIIHDSVHGSVKVDGAFLELLHRPEMQRLHGVKQLGLAYL
                     VFPGANHTRFEHSLGTYHVADLMCDALGLSKEDRDQALASALLHDLGHAPFSHTLEEV
                     LENRFSLDHTEIGAALIDGRRSVFRGDEEGIISCQGTISELLERNGISAEAVSDIIVS
                     PGHKARRGQSMITEDSGQSHFNSHDYLNQMLHGPVDADQMDYLLRDAHYTGVAHGTID
                     IDRLIHTIALHHGDIVVRKNGMVAAEGLMVARALMYTSVYFHKTVRIAEMMLCKAVEA
                     ADDSIAEGLQRESDASLVERLIAQGGHPRRIVTLLRYRQLYKRAYSVYVPDMSEEDAE
                     RLLPITEYRRRKTAEAMIAGRAGVDPSEVILDVPSRQLITGEVRQGKTEVPILNGEKV
                     RPLTRLSPISKALQSRGVHDWAVMVSCPERHVEKVERAAIRTLSDL"
     gene            complement(1362..1739)
                     /gene="sepF"
                     /locus_tag="PKM11_01880"
     CDS             complement(1362..1739)
                     /gene="sepF"
                     /locus_tag="PKM11_01880"
                     /inference="COORDINATES: protein motif:HMM:NF016363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HNX47294.1"
                     /translation="MPILKKPLGKGKDDVKSVETDQYIDLGALYFQEESSVSAGGIKI
                     AEIYRYEDVGPITQPVYQGNILMIDYSPIANDQNTLKRITNELKSVARDTNGDVAAIG
                     NNFIVVAPNGIRIDRKKIKGGYQ"
     gene            complement(1820..2314)
                     /locus_tag="PKM11_01885"
     CDS             complement(1820..2314)
                     /locus_tag="PKM11_01885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HNX47295.1"
                     /translation="MSEIRVRKRKRLREKELKALVDALRAATGVDIIGPKDTVDTAEG
                     PECELIIINNVIEGMMVDGRPFPTIRGLLKHKATKGFVSVDMGAVPYVTNGADVMGPG
                     IVEVDPDIKEGDMVWIRDMTHKRPLAIGKALVSAQVMVAKAPGKAIKNLHFVGDKIWK
                     YDER"
     gene            2419..3609
                     /locus_tag="PKM11_01890"
     CDS             2419..3609
                     /locus_tag="PKM11_01890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47296.1"
                     /translation="MKLPLVATRLIIIAFKLMVVAIVVLSIVPLLTGGIGLDLDGADN
                     ADMTMDDGTIRIDMPITVRNEGFFDINDLQVSFTFMDENGTLLAESEGEQVDIPVGGE
                     TEVPIALELDLYDLDRPTRSDLIFNGTDLKFDVKVSAKYTMDLVKLSVEAGSDMSWGP
                     FVNDLQVQEWNAQVTDEGDEQFVSVPFSFRADDAFNGLQAVTVTDYRDGNYTSNVTQT
                     VHMSSQVNEMAKIPISQEAYDRLMSGTANATVRTTLYVFDCSTYDDGNLNMGGGGGGG
                     GGGIGQPVKDLQPQMAGSFLAFDGLNYNVVVPYSYNTSPAYQGQEAHMLIEYWDDYGF
                     NVSIWQTVYLWDNSWQQVWLPLSPEAYDHVTNGNEVVHVRVTAFPWIILAEQTYSEPW
                     GAGP"
     gene            3606..4760
                     /locus_tag="PKM11_01895"
     CDS             3606..4760
                     /locus_tag="PKM11_01895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47297.1"
                     /translation="MNIGEFDKKYFSFPKGAVTATVHALKYLAIPYVLFTVGLIVLTG
                     QDGPQRVADLLIELQTVGLIFGIVLTALGFFKGAYPKGSYSRFLFGLTASVLVIVYVF
                     SMLLQGRVQDVIAKEAFELDLYLIFTLYFIPAILAVLMQFGEFADHRRPFLEKEGKLQ
                     VKEKEDPQDHRFYHDFRIRYGSLFNGLKLGRSTLTGFVLLPMVVIIILKAGMSSLDVQ
                     EVDSALSKLDDVSSLLIMLGVPMAALAFFKGFYPKGSFSRFLPSVIMVLISLYWIWTV
                     GLGGKFVFDAIEDVSIDLDFSKLLLLLMVGTGLWIVYYALELLLYRPEWKKGGFPKDL
                     LEERKARKEAQRKAKEERKAAKEKAKEDKKAAKEKKKADAETPTQDGKEP"
     gene            complement(4739..5911)
                     /locus_tag="PKM11_01900"
     CDS             complement(4739..5911)
                     /locus_tag="PKM11_01900"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HNX47298.1"
                     /translation="MITPDYPPRYTGGCAFSCQLLVEGLRSRGVHTDVWVFNGDPSPG
                     VSGEMGDTLFFRTSPTLGGLNRLAYGELRRRAPDCDIIHVYNTQQLPAAVKYGKKMNK
                     RVTATLNNLAPVCTNPSMYVEGECATCRPLDSLACAVRRPGPLWRRMLMPYHWVQFIW
                     LHRLSRSANGYIALSESTRQCYLDAGYDPQLIKLIPNMFDPGLCTGPSRPTNAGHNKV
                     ILYVGRLEAEKGLQVLIRAFALLNEGSVLYIVGKGGYEQQLKKLVDELGLEGKVIFTG
                     FMEKEEIGRYYAMADIFVHPALWPEPFPRTILEALSHGLPMLVSDSGSSATILGEAAL
                     SFGNGDHSDLAKKLQLLLDDDELCQITARAGREVLGRYHPDTVMSQIMEFYGSLPS"
     gene            6067..7326
                     /locus_tag="PKM11_01905"
     CDS             6067..7326
                     /locus_tag="PKM11_01905"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HNX47299.1"
                     /translation="MKVSIIGTGYVGLVSGVCFAELGHHVVCVDNVVEKVRRINEGVP
                     PIFEEGLEEMLGRHLASGSFRATNDYSEVPDTDITFLCVGTPSHEDGTLDLRYLLKAT
                     EDLGKALSKKKERHTVVVKSTVPPNTTRDVVGPLLLKTSGRTAEELGLAMNPEFLKEG
                     MAVKDFLNPDRVVIGASDDRTYEEVASLYDRIEAPLLRTDTSTAEMVKMASNAFLAAR
                     ISLVNELGNLCKSLGLDFREVAKGVGMDPRVGPLFLKAGCGFGGSCFPKDVRSIRAQA
                     RSLGVRTDMLDATLSVNERQPRRIIELLERRTEVYGSTVAVLGLAFKPGTDDIREASS
                     LTVVAELLRKGATVRAYDPQAMDNFKREFPQILYCHSAKECLKGADTALILTEWQEFS
                     DPSLYGSMLVVDGRGVTKTNNYEGICW"
     gene            7317..8198
                     /gene="galU"
                     /locus_tag="PKM11_01910"
     CDS             7317..8198
                     /gene="galU"
                     /locus_tag="PKM11_01910"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HNX47300.1"
                     /translation="MLVVMKAVIPAAGWGVRFLPLTKEQPKEMLPVIDKPVIQYVVEE
                     AVKAGIRDIIIVTGRHKRTIEDHFDRSFELESILKNGNRPALLESINRLHDLADLHYI
                     RQHEQRGLGDAVYQARHHVGNEPFAVMLGDTIHVSEVPVVKQLMEVHARTGKSVIAAE
                     RVPGDKVKDYGVLDAKKIDDRLYEINDLVEKPRPEEAPSDLCIAGTYVLTPGIFECLE
                     HTPPGHNGEVQLTDALRLLQKKEGMLAWEFVGKRYDIGDIPGWLDSQFELALRHPVYG
                     EKLRKRIRELNEKEHFL"
     gene            complement(8199..9023)
                     /locus_tag="PKM11_01915"
     CDS             complement(8199..9023)
                     /locus_tag="PKM11_01915"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HNX47301.1"
                     /translation="MFKKLLVPVDLSPQSMMMVDIATRMEGYGVKEVMIYSALDHVSK
                     RDPLLKALDESIGEAGLSHELVTEVRKEPAPAILKAAESHGATMIAMAASGKGRVKEF
                     IVGSTSLEVIRRSKLPVLLNKFPLEASDDPRGYREKSPPLLDRVLVTIDLSKASKAML
                     PQVQQLIDAGARKMTLFHVVQSAKYNMTDDKRFQEVKQKMETFQSKLDAKDCEIDVHL
                     HFGTTTYNILEATREIDATLIVLGTTGKGYLRGATLGSTSEEVIKGSTRPLLLIPT"
     gene            9152..10039
                     /locus_tag="PKM11_01920"
     CDS             9152..10039
                     /locus_tag="PKM11_01920"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HNX47302.1"
                     /translation="MTAAFDQAADRRTGAVLTTLLSSLMLGSSYVAVKMTVGDVNPFL
                     LGAATMAIGSVVLLVYMAIRGKLNRTMLKRWEFWVGPIINTGVVAPSYVGLTMTTASA
                     AGLIIGTNVVFVALFSRILFGERLGKRRLLGLGIALLGLITLTTRWNLSLLDGSQMTG
                     NLLVLISSICIGVSVVTSRIALRELTAEQWSLSLHLLLPPALLALFFIVPMDGGLSST
                     NLPAALFIGIVCTTLPTVLWTSALKHISVVTSATILMVESAFAVFLSWIFLGELIDIY
                     VITGAMMIFAAILLMARSE"
     gene            10475..10831
                     /locus_tag="PKM11_01925"
     CDS             10475..10831
                     /locus_tag="PKM11_01925"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX47303.1"
                     /translation="MHVLETSKLLTEEYTAKILMATMGRAKSAFELSDALGIPIAACY
                     RKIRVLEDAGLIRCSERRLTQSGKRMSMYKSMVRNANITFERNKIRARIEMEDGSSTD
                     DCLDIDLGMMFKESHA"
     gene            11065..13047
                     /gene="acs"
                     /locus_tag="PKM11_01930"
     CDS             11065..13047
                     /gene="acs"
                     /locus_tag="PKM11_01930"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF001208.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003987 - acetate-CoA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0019427 - acetyl-CoA biosynthetic process
                     from acetate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HNX47304.1"
                     /translation="MSDGKTIESVMEEVRRFPPSKEFSQQAHIKSLEQYQKMYKESVA
                     DPEGFWAKMASEELHWFAKWNKVHSWDKENAIIKWFEGGKLNVSYNCLDRHIENGRKN
                     KAAIIWQGENEDDVRTLTYQQLHTEVCRFANVLKSNGVKKGDRVSMYMPMIPELAIAM
                     LACTRIGAVHSIVFGGFSSESLKDRIADCGSKVLVTADGNHRGSKFVPLKANCDDALD
                     KGTSVEKVIVVKRAGAECSMEPGRDVWWHDEMVKADRSCEPVWCDAEDPLFILYTSGS
                     TGKPKGVVHSTAGYLLGASVSFKYIFDYHEDDTYWCTADLGWITGHSYIIYGPLCSGA
                     TTLMFEGIPTYPQVDRFWNIVEKFKVNIFYTAPTAIRSLMREGEKWPQGRDLSSLRVL
                     GSVGEPINPEAWMWYHKYVGNEKCPIMDTWWQTETGSILITPLPGAITTKPGSATLPF
                     FGVAPVIVKDDGTPAGVNEGGYLCISKPWPSIMRTVWGEHQRFKETYWVRFPGKYFTG
                     DSARCDNEGYYWIMGRVDDVIKVSGHRIGAAEVESALVSHHDVAEAAIVPVPHAIKGE
                     AIYAFVTLKNGVVETEQLRKELVAHVRKEVGPIATPEVIQFCPGMPKTRSGKIMRRIL
                     RKVATGTAEELGDTSTLADPGILDVLIQGSRALHKK"
     gene            complement(13080..14570)
                     /locus_tag="PKM11_01935"
     CDS             complement(13080..14570)
                     /locus_tag="PKM11_01935"
                     /inference="COORDINATES: protein motif:HMM:NF024832.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HNX47305.1"
                     /translation="MLGRRSFILFLSKMISAALAYVGLYFITRYLETDIYGTVTAAMA
                     LVATFNAVSDLGFSSAHIKRVSEGADPNQCISTFAFIKVVLTGLMVLITMVSIFVWTT
                     VMGNVLSGTSMQIIFLFILYQVLYDLSSIATVTFQARMEMAKMPLATLVEPLVRVPLV
                     IFVALNYMGVMELTLSYLVGSAVVFVVSMYMLLRERIKWTRPVLLRSYYTFALPLIII
                     TVISAVSGSADKLLITFFWNPTDVGLYAAPAVFLGVFATISTAVSTLTFPSFSKLHKD
                     GNLVEIRSLSKQAERYIAMIGLPVTILIMMFPYEVCEVLLGPKYIDSGRAIGIMVATT
                     FITMINAVHSSQIVAVGRPDISARITIVTVIMNISLMLLFIPGFGLGLSFVGAALALL
                     IGNFVSLLMVRYSVYRLTGTVPNVRLAYQLLAGLAAAGAMFVLDLFISIDRFYTLIIF
                     GLVAYAAFLLVLAALKEFTRMDVKYFLDLINVKKMFSYVGGELKGK"
     gene            complement(14617..15708)
                     /locus_tag="PKM11_01940"
     CDS             complement(14617..15708)
                     /locus_tag="PKM11_01940"
                     /inference="COORDINATES: protein motif:HMM:NF024110.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47306.1"
                     /translation="MRPKHVLVDLKGQARSFFRIKSNLFWVFAFPLLLIVIFGAIFSN
                     MGSEAVTLNVQNLDEGPGSQQMLAALNETGMVKLKFISPSTDLDQYVKDNSLAYVMVI
                     PANYSSNLASNVTATVELRLDETVSTSGTVFNAVNGVVNAMNLYMAGGDQYIVIEVGS
                     IVQKRFTFLDFFVPGIIGLTIMTTCVFNVQGTISRFRANGIFRKLATTPMTPFEWLLS
                     RILWHLFISFLTLAVIMGFGMLIFGMSMSVNLVVVLMIIAGSAMFSALGMIVARFVKN
                     EETASMAANAITFPMMFLSGTFFQLEMMPSYLQQIAKVLPLTYMSQGLRDAMVYDNLA
                     DAYFNLAVVAVIGVIFVIVAVLITKWEEE"
     gene            complement(15705..16622)
                     /locus_tag="PKM11_01945"
     CDS             complement(15705..16622)
                     /locus_tag="PKM11_01945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47307.1"
                     /translation="METVIEVRGLVKRYGDLIAVNGIDLDVKAGEVCSILGPNGAGKT
                     TSVEIMECLRKKTSGEVRILGHDIQKGQREIKKRIGVLPQSFNAFDYLTVKENIEYFG
                     GLFEKRIATDELIEAVQLQDKRNVWFTNLSGGLKQRVGVAIAMVNDPDLVFLDEPTTG
                     LDPKARREVWEVIRKLKSQNKTVILTTHYMEEAEVLSDHVAIMNDGRFIAMGTPKQIV
                     DQYGSGSTCIVKGANAAATEAVRSAGMAFESNHGDLLVRMDNKGSLAKLIGLLSSSEV
                     TYDEVLIKGSSLEDVFLKLTGKKLVEVEQ"
     gene            16741..>17075
                     /locus_tag="PKM11_01950"
     CDS             16741..>17075
                     /locus_tag="PKM11_01950"
                     /inference="COORDINATES: protein motif:HMM:NF013094.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HNX47308.1"
                     /translation="MKDRYARQLSIPGFGPQAQKKLSEASVAVVGVGGLGSPVCQYLA
                     AAGVGKLILIDDQKAEPSNLNRQVIHFEEDALLPRYKVESARLKLEAFNSDIDVEALP
                     MKLEEETSF"
     assembly_gap    17076..17175
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17231..19090)
                     /locus_tag="PKM11_01955"
     CDS             complement(17231..19090)
                     /locus_tag="PKM11_01955"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF014594.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47309.1"
                     /translation="MGRDWEKEYRSKILTAEEAVLKIGPGRTVFLGTACGEPQALVKA
                     LLAKSYAMIDSEVIQTLSLGLTFYAEDQFRDQFRLNAFFIGPNVRGAVNEGKADYTPV
                     NLSDIERLFSSGLKPVDVALIQVSPPDDDGYCNLGVSVDITMSAAMHADVVIAEVNPN
                     MPRLGGNSRLHMREIDHFVENDQPILEFVGEGEVSRTAPRIGKNVAELIPDGATIQIG
                     YGNVPDAILAYLDEKKDLGVHTEMFSDGIIDLVEKGVITGRRKGFHDGKVVSSFCMGS
                     KRLYDFIDGNEMFEMYPSSYTNDPCNISRNNNMIAINSALEVDLTGQVCTDQIGHRFY
                     SGIGGQADFMRGAARSPGGKAIIAMPSTAQHHTISRIVPTLSAGGGVTTTRGDVQFVV
                     TEFGVADLRGKSIMERSLSLIGISHPRFRAELLMNAKSLHYVYQDQMEAGYVGIYPEQ
                     YESVRVVADQEMYFRPAKPTDEPMLKEMFYSLSRDTVYNRFMGLKRSMPHRELMRIVN
                     IDYDTRVTVCGFVIEDEVWSMTSFAMYDLDKASNTAEISFAVSDKWQNKRIGTMLMDI
                     MIAIARDRKIKAFTAELLGENMRMLDLFYRTGLKVETRLMEDTYLVTIDLWSK"
     gene            19187..19408
                     /locus_tag="PKM11_01960"
     CDS             19187..19408
                     /locus_tag="PKM11_01960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47310.1"
                     /translation="MIIELWILAVFLVLIGILVLVIVVSSLIKFFTAIVAAIFVLMFT
                     GSGLLAGAAFLVVAIIVAVARLANPYLRR"
     gene            19432..19698
                     /locus_tag="PKM11_01965"
     CDS             19432..19698
                     /locus_tag="PKM11_01965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47311.1"
                     /translation="MELSSVDKKRVISKDGRELGVLYGSTIDTGKWTVLHILVNVSKD
                     AAKELHIKKKLFKPIIINVSTDLVAVVGDVIQLRSTMKELDELF"
     gene            complement(19695..19856)
                     /locus_tag="PKM11_01970"
     CDS             complement(19695..19856)
                     /locus_tag="PKM11_01970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47312.1"
                     /translation="MVEAKPREGKSKCTVCESFDLKGTWTCECDAVNISRDAKCWRCG
                     RPRFDNERV"
     gene            complement(19904..20422)
                     /locus_tag="PKM11_01975"
     CDS             complement(19904..20422)
                     /locus_tag="PKM11_01975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HNX47313.1"
                     /translation="MDDIGLVHVYTGDGKGKTTAALGMCVRAVGHGYRALIVQFMKTA
                     GTYGENFLDLPGLDVVASGNDCLVFSKDITQADLDRAAEGLELAAEALRSGRYRIVVL
                     DEVSVAIKFGLVNVNEVVKAIGGRHQGVEAVITGRHAPPELLDMADYISEVEAVRHPY
                     QKGITSRKGVDR"
     gene            complement(20424..20996)
                     /locus_tag="PKM11_01980"
     CDS             complement(20424..20996)
                     /locus_tag="PKM11_01980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HNX47314.1"
                     /translation="MKVVAFNGSPRVNGNTHQALEFVLQELKNEGFDTELIDICREDI
                     KPCRACGSCGKNKDQRCVMAEDRLNEYVQKMKAADGMIIGSPVYFGNMTAQTKAFLDR
                     AFYVARANGDMFRRKVGAAVAVNRRAGALDTFDEINKLFLISQMIVPGSSYWNTITAL
                     KPGDIAMDEEGIRTMKTLGQNMAWLLKKLD"
     gene            21083..21715
                     /locus_tag="PKM11_01985"
     CDS             21083..21715
                     /locus_tag="PKM11_01985"
                     /inference="COORDINATES: protein motif:HMM:NF013933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HNX47315.1"
                     /translation="MKGEATMGAFWEGLIAGYGIAIPLGAVSILIVNTALDRGFRLGL
                     VAGAGTATVDLLCAALAVFAGTAAVAFIAPYSGPLQVASGIALIAMGVYGILRLRRRV
                     KDSVPDTGNQDGEITVYGKFVALTLLNPFTVAYFLALILGKGASWSFSFGDCLWFIAG
                     VGLASLSWETLLAAVGALARKHLTPRFMTASILIGNSIVILLGLRIMMAL"
     gene            21826..22509
                     /locus_tag="PKM11_01990"
     CDS             21826..22509
                     /locus_tag="PKM11_01990"
                     /inference="COORDINATES: protein motif:HMM:NF014007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HNX47316.1"
                     /translation="MLLGEVNTHIPDGLMDPVVVGLGWAIALPFIALAVYKLNKKVDE
                     RMVPFMAILAAGIFVAQMLNFPVGGGTTGHLVGAALAVILLGLYGGILVLTTILVIQC
                     LVFGDGGLTALGLNLLNMAVIAPLVSYGVLRLLKKHQSLAVPLAAWASVFLAALACGL
                     LLALSYTISGGDFGIVASVSIPAMAGWHAIIAIGEALITTGVVVFISRVAPEMLEMGK
                     NQEVKEAVV"
     gene            22506..22784
                     /locus_tag="PKM11_01995"
     CDS             22506..22784
                     /locus_tag="PKM11_01995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="PDGLE domain-containing protein"
                     /protein_id="HNX47317.1"
                     /translation="MNWKSYGKATAVILVLFAIGLVGYFAFSAAFPDGLEKVMEDNHV
                     EEAEQVWTAPLSYGENWAGALIAGLIGFALTFLLVFLYLKGMRSRQKA"
     gene            22840..23568
                     /gene="cbiQ"
                     /locus_tag="PKM11_02000"
     CDS             22840..23568
                     /gene="cbiQ"
                     /locus_tag="PKM11_02000"
                     /inference="COORDINATES: protein motif:HMM:NF014420.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0032778 - P-type cobalt transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HNX47318.1"
                     /translation="MQKHADGHARDSALSRFDPRVKLVCIFALVVLISTFTDRNALVL
                     ALIFTIVLMLLSRVSMTHLLRGLLMALPFIAFASLTMLLTSGAETALAMGLRVSTSVL
                     LLLLLVYTTPFMDLLWTMRWFKMPSLLSDMIMFTYRFIFVMLDEAERMRMARRSRGFQ
                     GGRSLLDREAFKVLSNTIGMIFIRSYRRADRVYMALLSRGYDGKVRTLSAFRVRLRDA
                     GLGLAFVIIGGFSLSQQMGWYVWW"
     gene            23559..24371
                     /locus_tag="PKM11_02005"
     CDS             23559..24371
                     /locus_tag="PKM11_02005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47319.1"
                     /translation="MVVISLRDVSFEYPGHIQALENISIELKEGERIALIGPNGAGKS
                     TLLHLMAALDFAKQGDVYIAGKKVERRAAAEARKKVGFLFQDPDDQVFMPSVYEDVAF
                     GPLNMGLAEEEVRERVDKALEAVGATHLSKRVPQNLSLGEKKRVAMAGLLSMSPPVLL
                     LDEPTANLDPQGRRDLVNVLSGLEQSMVIATHDLTVAFELADRAIVLKRKVLFDGTFR
                     DLMKRPDVLKEANLELPSFSRLMVMYKQHTNGDFEPPLTVEEAFEVLKANLR"
     gene            24489..25745
                     /locus_tag="PKM11_02010"
     CDS             24489..25745
                     /locus_tag="PKM11_02010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47320.1"
                     /translation="MDPIRRGLGKAHLLWNRWTIFGVMALTYFLVYFHRVSPAVLATD
                     LQGSFGVGLTAVALLSSAYFYAYMVMQLPCGVLTDRWGPRRTVCAFTALSALGALVTA
                     LASSFEMVVAGRVMIGLGVAMVYVPTLKVLSSWFRKDEFSTMTGVLLMIGNAGGLAAA
                     GPLAAMSDQVGWRQVFLVLAVLTAVLTWSMWLLVRDRPQDVGLPAVERTEEEDRIPMG
                     SALRQVFSSGIRFWPFAIIFFFMYGSLMVYQGLMGGPYFRDVLGWDKAEYGFSLTFVG
                     LGMIAGCPVSGYLSDRVLRSRRKVVVAGTLAFAMMWGILWLMSGRVNDQMAYTIVHFL
                     FGFFAGWYVPIYGQVKDAFPRSMSGTSLAALNIFPFAGGAVLQMIAGFMMSESSLTEY
                     RAVWLLMLFGMIVAAIAALISKERPS"
     gene            complement(25773..26558)
                     /locus_tag="PKM11_02015"
     CDS             complement(25773..26558)
                     /locus_tag="PKM11_02015"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: protein motif:HMM:NF014641.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006782 - protoporphyrinogen IX
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HNX47321.1"
                     /translation="MKKVVAIIGPSERWMPLCREHRQLADFVCASPLRAEPNDDSNFS
                     LFLIDMFSGRFDVLVATCPTAIEALVTMAKRRKMLDRAKEAMGRAELVVIGDRTAQSA
                     QRHGLKVSSIAPESTTEALVQHLGSQARRGTVALLRSDQGSKRLVEDLKATGWKVEDV
                     PVYSLLLDEGEDMQDIMERLDRGDIDALVFPTPAHTQAFLVQLEERSGEDEALSLLEG
                     LTIAAMGQETRERLEAYGIEVNVVPEKAEPSALLRKLMGHLDV"
     gene            26641..27063
                     /locus_tag="PKM11_02020"
     CDS             26641..27063
                     /locus_tag="PKM11_02020"
                     /inference="COORDINATES: protein motif:HMM:NF013098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HNX47322.1"
                     /translation="MPIGDPMASNDPREEKGRLTRVWMVGVPVNDLDIALDFYMQKLG
                     LELRRRDGNWAELGPGEPMGKVALYVPREGERQPGGMSGVVFSCDSMYDMHRRLVDEG
                     VVFKLKPEKQPWGGLMAVLLDQDGNELMVLEHPDRYRK"
     gene            27117..27896
                     /locus_tag="PKM11_02025"
     CDS             27117..27896
                     /locus_tag="PKM11_02025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47323.1"
                     /translation="MLEIENLTVEVGGREILHNLSLSVMTGYTTVLFGPNGSGKSTLL
                     MTIMGFSGYKVKSGRILLNGEDITHMPVNERAKRGIGMMMQRPPNLTGVRLKDLVRVT
                     SKGNVDTDKVAEELDMARFMERDVNVGFSGGEIKRSEILQLTAQNPCLVLLDEPESGV
                     DMVSIEKLGAKVHDLLTGPTHCAGWREKSGKAALIITHTGQILDYVEADRGYVMCQGT
                     VACSGNPRELLAEIRKMGYQECISCKVNKAVQIKENAISEV"
     gene            27899..29116
                     /locus_tag="PKM11_02030"
     CDS             27899..29116
                     /locus_tag="PKM11_02030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HNX47324.1"
                     /translation="MTSNDENRAKDALKKQAKFGEDIDLDSYHDGKRDIAEMESLEDL
                     PKDTKETMHDSGLTPSGKGRSGNFLLMDNSVVHSAIMGEGVELMPLRQALKVHDWLKD
                     YVWKAVQPDADKYTAETYLAKADGYFIRALPGAKVKMPVQTCLLLKNRNTKQYVHNVL
                     IAEEGSEVEVVTGCATTKGVEKGLHLGISEFYLKKNSKLTFTMVHNWSEFIGVRPRTN
                     ILMDEGATFINNYVALKPVKTIQTYPTAHMNGANGICRFNSVAVAHPGSVMDLGSRAI
                     LNAPGCKAELISRTITTGGTVIARGQLVGNAPGIKAHLECKGLILNNKGVQIAIPELE
                     ARVPDVEMTHEAAVGKIAQDQVEYLMSRGLTEEEAVGMIVRGFLDVGIRGIPDHLKAE
                     IEKILQETDVRGS"
     gene            29222..29671
                     /locus_tag="PKM11_02035"
     CDS             29222..29671
                     /locus_tag="PKM11_02035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47325.1"
                     /translation="MQVETAVHTALKTMRGVERDQIARFLIDPVVLFILAATSRRCLT
                     VSEMAPVVNLPAATCYKLIYQMDKMGLVAYCGNGRNGGRGKAAAYTSVLKEMHLEMRN
                     TIIVLRVTWKNGTNEEFRKDLVPPSADKCPFEVVSLLTAEADSAFSD"
     gene            29715..30509
                     /locus_tag="PKM11_02040"
     CDS             29715..30509
                     /locus_tag="PKM11_02040"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF016362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HNX47326.1"
                     /translation="MRVVKRSGELEDFDPAKAINAILRVGTSPEEAEAILESVKPYLY
                     DGMTTEELYRRIRSRLPAPQAQQYSLKKAIMLLGPEGHAFESLMGRVFEQMGYQVLVR
                     QILKGRCVSHEVDVVIVKDGKKATVECKFHNALGTKSSIQEALYTWGRFLDLKDTNNV
                     EKPWLVTNTKFSSEVVRYACCMGMHLIGWKYPEDGGLERMIDEAHIYPITVLDIRRSE
                     QRTLLYHDFVICDDIVERKPELLGLFPRETGERIIKKTEEFLRNVR"
     gene            30509..31597
                     /gene="wecB"
                     /locus_tag="PKM11_02045"
     CDS             30509..31597
                     /gene="wecB"
                     /locus_tag="PKM11_02045"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: protein motif:HMM:TIGR00236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HNX47327.1"
                     /translation="MRFSVVLGTRPEIVKMSPIVRELQRRGLDFDLVHTGQHYSFEMD
                     RVFFRDLELPEPRINLEVGSGTHGAQTGKMLAGLERFFQETRPDVVLVQGDTNTVLAG
                     ALAAVKLGITVGHVEAGLRSFDRTMPEEINRVMADHVSDLLFAPTEMSARNLRAEGLP
                     EKRIHITGNTIVDAVRENLEIAGGKGDVLGTLGLRKGVYILTTLHRQENVDSRERLAN
                     VLIGLEKAGRETGLDVIWPMHPRARKNLETFGLRLPENVRPITPLGFLEFLQLEGGAA
                     LALTDSGGVQEESCILGVPCVTLRDNTERPETVDVGANVVVGTDPSRIIAGVRSMLSR
                     KGGWTCPLGENGAGGRIITICQERRNQR"
     gene            31641..32276
                     /locus_tag="PKM11_02050"
     CDS             31641..32276
                     /locus_tag="PKM11_02050"
                     /inference="COORDINATES: protein motif:HMM:NF016831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX47328.1"
                     /translation="MIEAVLEVDIPDSWVHDISANFNVPVRILDCIHFGEHGARSFVE
                     LECNDPEMQQIVSRAIEKHPDVCKWEPAIAEDGRMRGIALLTKCRACKAVMRSDCYLR
                     SAKTIGNGKVEWQIIASREAALGALIDELKKNGCAITLRSKKTLDDTSFVTKRQEVVV
                     HAALMNGYYDYPRGVSLQQLAKSFDVTTSTMGEILQRGERNIIREYFRTKM"
     gene            32287..33126
                     /locus_tag="PKM11_02055"
     CDS             32287..33126
                     /locus_tag="PKM11_02055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HNX47329.1"
                     /translation="MDDSDKIEVTTMDEKDYRLKKSLAKIKHKIVVMSGKGGVGKSTV
                     TVNLATALAMRGYEVGILDADIHGPNIPKMLNIEHEDVISDEDGLLPVLVPPHMKVMS
                     MAFLLQDPDTPVVWRGPIKMGALRQFVAEVKWGDLDFLIVDLPPGTGDEPLTIAQLLE
                     DADGAIIVTTPQDVALLDSRKSVTFAQALKMPIIGIVENMSGLICPHCHNTIDLFKTG
                     GGERAAEQMGVPFLGRIPLDPNVVLGGDDGSPIVLQDKSNPASKAFDEMTEKVLAKVN
                     GGK"
     gene            33127..>33440
                     /locus_tag="PKM11_02060"
     CDS             33127..>33440
                     /locus_tag="PKM11_02060"
                     /inference="COORDINATES: protein motif:HMM:NF014620.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HNX47330.1"
                     /translation="MVRLLVTAEGPTLDDLVEEDFGHARYLIIVNPETWEFEAHENIK
                     KQTDMGHGIMTAENVAKLKPDAVLTGYAGEHGRAKMQDLGIRMIMDEEGTVRDAVNGY
                     IR"
     assembly_gap    33441..33540
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            33675..34397
                     /locus_tag="PKM11_02065"
     CDS             33675..34397
                     /locus_tag="PKM11_02065"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HNX47331.1"
                     /translation="MNHRILLPTNGSLPALVATKEAVRLAKEKGAMLVILKVVEQDPA
                     MYLEQVSEDLGLRGGTGVDGVIFAQALAAEAGVGSEIIEREGAVTGEIIRAAEECQVS
                     MIVMGSSNPRGLAGLYLGNVAEAVTKRAKVSVYIVKPTEEDLEMALKLAKTPLPTPEE
                     NALRSIIRSRKFKVGLGLFGIYGVLYTTFTVLGTFGRDIMGTRLAGLNVGLIMGMTVI
                     LLAIVMAVSFNYYAVKVEKEGQ"
     gene            34398..35912
                     /locus_tag="PKM11_02070"
     CDS             34398..35912
                     /locus_tag="PKM11_02070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation acetate symporter"
                     /protein_id="HNX47332.1"
                     /translation="MAAVLDNSFKPLAFALFMLITIATMAISVYFSRRVRTAGHYYVA
                     GGGVKWFVNGIAFAGDYLSAASFLGVAGMIAFSGFDGFMYGIGFLAGWIVALFLIAEP
                     LRVMGKYTFADALVHKFKSKRVRLAAAISTLVVSVFYLIPQMVGAGTIVQPLIGLDYA
                     WGVVIVGGIVILITATAGMVSTTWVQFIKGLLLLVAALGLTIAVLVLSGFGPLEFITH
                     FLENGASNPSTGLYSHSGDVFLAPGIKFTNPLDYASLALALILGTAALPHILIRYYTV
                     PKPSDARKSTVVAIIAIGAFYIMTLFLGLGANYFAGQGEFLINDSNLSAPTLANFAGG
                     EVFFAIISSIAFATILGTVSGLIMAAAGAIAHDLYTEILGKKTNERSALRVSKLTAVG
                     VGVIAILLGILAEGMNVAFLVGLAFAIAASANIPALICTLFWKGATEKGIVTGIFTGL
                     VLSIVLIVISPTLMADPFFSLNNPGIVSIPAGFAVTIGVSLLDKKKQEVSVATN"
     gene            complement(35974..37131)
                     /locus_tag="PKM11_02075"
     CDS             complement(35974..37131)
                     /locus_tag="PKM11_02075"
                     /inference="COORDINATES: protein motif:HMM:NF014692.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase iron-sulfur subunit"
                     /protein_id="HNX47333.1"
                     /translation="MSKGSQRMGIYICRCGGNIDNSLDTGRLHEAAKKLTKVAHTAVV
                     DFACSPAAREQIAKDAKEHGIDRVLIAACSPKLYLKEFQQALEEADRKGCMLEMCNIR
                     EQCAWIHFNDREAATSKAEDMLRMSHDRLQNQSMTEKANVAQVNKFRCTGCGICESVC
                     NFNAIHLAPDKDYQDHKKANVNINACEGCGACVAACPTAALDQTCFSNLQMLSQIETF
                     LKDSKMGFPKVVVFSCHWCSYTAADVAGLKRMAMDPHFCVLRTMCSARVDPEWVLKAL
                     SKGADGVLVLAGHPGRCHYEIGNLRTRKRMTLLHTYLGQMGFHPDRFHIDYIDSEEVE
                     GYVKAVNGYIEKVRQLGPNPIDPNTRVSPKRLEMPWLDIKAEKKWSDDLKL"
     gene            complement(37236..37835)
                     /locus_tag="PKM11_02080"
     CDS             complement(37236..37835)
                     /locus_tag="PKM11_02080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HNX47334.1"
                     /translation="MPSESMKKTIENLAKAFVGESQARNRYTWYAKTAKTEGYEQISA
                     VFLETAEQERSHASSLWKMIQNLKKKENLGFEAMHFEAEFPAVQGCTADNLKAAIAGE
                     NYETESMYPEFADVAEKEGYADIAVRLRAIGRAEKHHETKYQKLLALVESGNVFKEQK
                     STKWVCRECGYEHEGTEAPEKCPSCEHPRSYFQRRCVDL"
     gene            37962..38390
                     /locus_tag="PKM11_02085"
     CDS             37962..38390
                     /locus_tag="PKM11_02085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47335.1"
                     /translation="MTDKVNFDDLSVVEQALYIIDNYADIFLDNLGLGLNRRRILNIM
                     YEARKQLMREWNFPKLVMVLAFLQETFHQDLEVEIGIFNFLRPLSREEAESTAALKAE
                     QHFEMENFRLALVYYQLLENESGEGPASEKVQECLALIDK"
     gene            complement(38396..39283)
                     /locus_tag="PKM11_02090"
     CDS             complement(38396..39283)
                     /locus_tag="PKM11_02090"
                     /inference="COORDINATES: protein motif:HMM:NF016228.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HNX47336.1"
                     /translation="MHRVMVIGASGLLGQYMMSAGTQLGLAMVGTYNTVKDGSPSAMH
                     MDVTDPDSVSRGISAASPDLVLLPAAMTNVDQCERQPDAAYKVNMEGTLNVAAECRSA
                     GIKLVYVSTDYVFNGLKGGRYHEFEPADPLSVYARSKLEGERVTLDAGRGNLVCRVSV
                     VYGWNRIGNKSNFVTWIIDSLRKGQGIRLYDDQFVSPTYAPSAANDILQLGLGKLKGI
                     CHTSGPDCLSRYQIGTAVAEAFDLDDSLIRPVRTEDMPLLAVRPKRSCLAVDLAESEL
                     GRPMTDLKKGLELMRASEI"
     gene            39403..40845
                     /locus_tag="PKM11_02095"
     CDS             39403..40845
                     /locus_tag="PKM11_02095"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47337.1"
                     /translation="MSDVCDGEPIDKLTLKGNGIILLNMAMMAMMVMFVEIMLVPALP
                     LIAQEFPQDASWIAWVLAAYMLVGAVATPLIGRLGDMYGRKRILLVSMSFYMLGLVGC
                     AFAWSIPSLIAFRAVQGLGMGMFSLAFGIVRDTFPTKVIPMALGLISAMFSVGVSIGL
                     LGGGLIIQTFSWRESYLIITPLFVIMVLIAWRTLRDDRKHCSAGLDLAGSALLGVAVL
                     LLLVSLTQGEKWGFTDLRTVGMVVASIVLFASFAIWERRTSNPIIQMSLLLNRGILGA
                     NLVALFYGVAMFLLTQTIPFFLRSPQNLGGFALTDTFVIGLYMVPMALTQLVFAPAAG
                     SWSKKYGADKVLIAGMAVFAIGIGLLIAWHSEDWMIWVAMGVQGIGMALAMVSFINVV
                     GMAAPKGDFGVASGMNSLFRIVGGSIGPVLASAVMAGYAVMVVLPFHTVEYTSEEGYV
                     VSWAVGAAFAVVGLIIALLVRPGRGISYQD"
     gene            40888..41442
                     /locus_tag="PKM11_02100"
     CDS             40888..41442
                     /locus_tag="PKM11_02100"
                     /inference="COORDINATES: protein motif:HMM:NF014573.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HNX47338.1"
                     /translation="MKIVFVNGSPRPEGNTGTMMKALAKKAKERGAEVAYFEIVDKDV
                     QDCDGCYRCDTEERCHKDDDMTDAYSLIQSSDMLVIGSPIYMGVETGITKCFVDRLYY
                     LMAQKRLARGKKAIALFTCGLADGHMVYGFMHGRFDKLLRLDLGFEEVKTFIVSGTRN
                     RVDLDDNYYAQETLKEMEKFIFPE"
     gene            41444..42454
                     /locus_tag="PKM11_02105"
     CDS             41444..42454
                     /locus_tag="PKM11_02105"
                     /inference="COORDINATES: protein motif:HMM:NF013168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HisA/HisF-related TIM barrel protein"
                     /protein_id="HNX47339.1"
                     /translation="MDEEVVGCQHCGSRRIVPKVLVGGPMAGVDNKDGSYICLDCGRE
                     LVPLGFEGETERQDFVAHAQSAGKDFLHIPIVPVDTWALFNIPFLDIPVVKVAKVVEV
                     EWRDGWNVRPGGVPFADYWKAVGSKRYGADDVLLMDLAGMQHARPNFEALKALMKRKY
                     AVWLEMGVRNVQDLFDAFTLGAQNVLLGSLTCPSKSMLEEVIELSDMSIPLLYYDGKV
                     LWSGKQLPSDLSASLRMLADLGFDKAAVLDLRRLGGKDGYDVDLLDLALSSDLEMLFG
                     GGVREPDLPELRDKGAVGGLLEPYTPVLRSLIASQGVPADDEPLPTPVSRESPRGFGI
                     DG"
     gene            42510..43268
                     /locus_tag="PKM11_02110"
     CDS             42510..43268
                     /locus_tag="PKM11_02110"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
                     /protein_id="HNX47340.1"
                     /translation="MEIWELAVVILAAVVPSLIYLVWIRNSEKYNRERWMHVLSVFLF
                     GAIISIIAAVLLESVAISLFYASGSIFSGGFWSYEPYDPTLEIVILAVVIAPLVEEWT
                     KGWGVMTVRNKIREPEDGFIYGAAAGLGFAAMENIFYNSSALVGGFDVFLTTALIRAV
                     ASTLLHASASAVLGYGIARKYLNGAKGRRTGYLPYYLAAVVLHGLFNGFAVAGEVVDH
                     YAIPIIGLVSSTVLAIGMFLWMRRRLRIMDRRWN"
     gene            complement(43246..43818)
                     /locus_tag="PKM11_02115"
     CDS             complement(43246..43818)
                     /locus_tag="PKM11_02115"
                     /inference="COORDINATES: protein motif:HMM:NF014573.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HNX47341.1"
                     /translation="MTLVIGLNGSPRRNGNSATLLDQALDAARDSGAEVIRYDLASLN
                     ISPCQACEDCFINGSCVIRDDMDALYDSLEEADAVIVASPIYFSGMSSQTKIVVDRCQ
                     ALWARRKVLQDGRKPGVGAIILTGAQPNARFDNAVSELRAFLIGIGIAPGPVLKVAGA
                     DGAAYSAEHPEVRASARALGTELVSSISGP"
     gene            complement(43815..44192)
                     /locus_tag="PKM11_02120"
     CDS             complement(43815..44192)
                     /locus_tag="PKM11_02120"
                     /inference="COORDINATES: protein motif:HMM:NF012301.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HNX47342.1"
                     /translation="MSQNARLSVLMVEDNPAHADLCREHLSQEEFELFVARTGSEALA
                     MAKTRPYDVVLLDYLLPDTNGMDLLPRVRGLQPNSIIMFVSAVDDPDLSYQAMRAGAS
                     DYVIKGLGYFKELKVRIREACEE"
     gene            complement(44235..46631)
                     /locus_tag="PKM11_02125"
     CDS             complement(44235..46631)
                     /locus_tag="PKM11_02125"
                     /inference="COORDINATES: protein motif:HMM:NF024583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX47343.1"
                     /translation="MSLEEGGRLGDRVGRTMICTLDLNGRLKYYNRTVEALLATDESR
                     LLGTALVSLLQNGTAPLMDAALQQCLQGRSNRERLTMELGQARFLVSVTPVKEREEIV
                     GVSLIGFLTDDDKRELTLDLVLDILQDHDLMVMVYSRDGYIVSTNSPFQRFLEVDRDI
                     LDGNELTFVLHGDEEEAKKVAKALVQPDLPSFATLTMKVQGRAVKLTWSLHPFLRDGK
                     DLVLAVADPPILRGRLGPGNEALMFLAESSTDLISEGNPKDTLQSELDNLLRREGLDF
                     AVMRLLGWDGRPQLFCSGIDFKQARELFETQVGDSSLAVKMAKGESCTCSALNTDCCQ
                     ATSDLGFQSLVCLPLRFRGDFVGAGLFGKKAPIEDLETRKLTLQVFSNQMAMIYFYSL
                     LNQHYQRVGSEFQTLFEISRLVSGTLDYREVLDIILSKSRELVESDNCIIYGFDRGGT
                     RLIPLTYLSKYEVDPEALAIDVGEGITGDVARTGKGELVERADLDERAKQVDGTPEEP
                     SSLICVPLKIGDEMLGVMTLEKVPGKPFTQDEYRLMELYSLHAAMALKNSGRFQDIKS
                     KVSAQKIYNILLTHDVANYNVPIHGFLEMLIKDPKLDERQRRYVKSALAQSQNISNLI
                     TDVRKLWNILESDASVELVPVDLVPLLHDIVREIKTSYLFSDIPLELQYPEGEALVMA
                     NPLVRDVFFNVINNSAKYGDMKKVEVVMRPDHIGDVGYWRVEVRDQGKGIPEERKPQL
                     FQRFENLDTGMAAESHGLGLSVVKALVDRYQGKVWVEDRIKGDHTKGSIFVIMLPKAR
                     "
     gene            47055..47828
                     /locus_tag="PKM11_02130"
     CDS             47055..47828
                     /locus_tag="PKM11_02130"
                     /inference="COORDINATES: protein motif:HMM:NF013429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HNX47344.1"
                     /translation="MNSPMRLGAMATLRDHEMISALKVDFLELLVLPGDDIPAIRSFC
                     ESFDGELILHAPEEFSDGRLLDLSSLDPSWREASVRRVREVTKAGEGTARPVVIHPGG
                     ITERPLDDVSGIMTSLQASLDALPDYTWLENMPMHYHHRGRTLCSNLMRTPSEMKQVD
                     ALVAGFTVDVSHAYLGVAKNGNDNVRAMFQELGEAVRHVHLSDARRPDVEGVMIGDGE
                     IDMSFFPYLRGLPVLLEVWDGHLDGGAGFREALKRMRGQ"
     gene            47902..48975
                     /locus_tag="PKM11_02135"
     CDS             47902..48975
                     /locus_tag="PKM11_02135"
                     /EC_number="1.1.1.261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent glycerol-1-phosphate
                     dehydrogenase"
                     /protein_id="HNX47345.1"
                     /translation="MLVLDDGDFTKARSMLFPRQVLAGHDIIGTVPDSCKDFGLSGTA
                     LIVTGDKTMKVAGNAVRDGLVANGYEVQIVNVGEATNDNLDIVMKAAHECQADFLLGV
                     GGGSKIDLAKMAATNLGKEFLSIPTSASHDGIASGRASIRSVSGPISHEARVPLAVIA
                     DTGIIAKSPYRLLAAGCADVISNATALMDWEFARRLRYEEFSRSAYALASYTAQTIIE
                     NADLIRPNLEESVWIAIRPIIISGISMSVAGSSRPTSGSEHMFSHALDLIAPGKALHG
                     EQCGVGCIMMMYLHGGDWMRIREALTKIGAPTSAKELGVSKEQVIEALVTAHQIRKDR
                     FTILGMGLTREAAERIATITRVI"
     gene            48993..>49180
                     /locus_tag="PKM11_02140"
     CDS             48993..>49180
                     /locus_tag="PKM11_02140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0179 family protein"
                     /protein_id="HNX47346.1"
                     /translation="MITVIGERQAKVDGRFIYLGPLTECKECKLKGVCFNLDAGAPYR
                     IVEVRDVKHECKVHEDGVR"
BASE COUNT         9946 a        14085 c        14647 g        10302 t
ORIGIN      
        1 agggttagag gtcgctgagc gttcggatcg ccgccctctc caccttttcc acgtgccgtt
       61 ccggacagga gaccatgacc gcccagtcgt ggaccccgcg ggactgcaga gccttgctta
      121 tcggactgag ccgggtcaaa ggtcttacct tctccccgtt cagtatgggc acctcggtct
      181 tgccctggcg gacctcaccg gttatgagct ggcgcgacgg aacgtccaag atgacctccg
      241 aggggtccac gccggcccgg ccagctatca tggcctcggc cgtcttgcgc cggcggtact
      301 cggtgatggg cagcaacctc tccgcgtcct cctcgctcat gtccggaacg tagaccgagt
      361 aggctcgctt gtaaagctgg cggtaacgga gcagggtcac gatgcgtcgg ggatggccgc
      421 cctgggcgat cagcctctcc accagggaag catcgctctc ccgctgcaat ccttcagcga
      481 tggaatcgtc ggccgcctcc acggccttgc agagcatcat ttcggcgatg cgcacggtct
      541 tgtggaagta gaccgaggtg tacatcaacg ctcgggcgac catcagcccc tcggcggcca
      601 ccatgccatt cttccttacc acgatgtcgc catgatgcaa ggcgatggtg tgaatgagcc
      661 ggtctatgtc tatagtcccg tgggccacgc ccgtgtagtg agcgtcccgg agcaggtagt
      721 ccatctggtc ggcgtccact ggcccgtgca gcatctggtt gaggtaatcg tgtgagttga
      781 aatgagattg cccgctgtcc tcggtgatca tgctctgccc gcggcgggcc ttgtgccccg
      841 gggatacgat gatgtccgac accgcctcgg ccgatatccc gttccgctcc agtagctcgg
      901 agatggtccc ctggcaggat atgatgccct cttcatctcc acggaacacg ctgcgacggc
      961 catcgatgag ggctgccccg atctcagtgt ggtccaggga gaagcggttc tcgagaactt
     1021 cttccagagt gtgagagaac ggtgcgtgtc ccagatcgtg cagcaacgcc gacgccagag
     1081 cctggtcgcg atcctccttg ctcagcccga gcgcgtcgca catcaggtcc gcgacgtgat
     1141 aggtgcccag ggaatgctcg aaccgggtat ggttggcgcc cggaaaaacg agataggcga
     1201 gaccgagctg cttcaccccg tgcagcctct gcatctcggg acgatgcaat agttcaagga
     1261 aggcaccgtc caccttgacg ctgccatgca cgctatcgtg aatgatcttc tgactggaca
     1321 tgaaaaaagt gagctggggc cccgggatgg gggccggggg cctactggta gccgcccttt
     1381 atcttcttcc ggtcgatgcg aatgccgttc ggcgcgacca cgatgaagtt gttgcctatg
     1441 gcggccacgt ccccgttggt gtcccgggcc acggacttca gttcgttggt tattcgcttc
     1501 agggtgttct ggtcgttggc gatcggcgag taatcgatca tgaggatgtt gccttggtat
     1561 actggctggg ttatcggacc cacgtcctcg taacggtata tctcagcgat cttgatgccc
     1621 ccggcggaga cggagctctc ctcctggaag tacaaagctc caagatcgat gtactggtcg
     1681 gtctccacgc tcttgacgtc atccttcccc tttcccagcg gtttcttgag aatcggcatt
     1741 gcatccctcg gttggcaaag ttatggcatc taatcaatat taatctatct gaatcgcacc
     1801 ccagcaatgg cttggcggct cacctttcat cgtacttcca gatcttgtcg cccacgaaat
     1861 gcaggttctt gatggccttc ccgggggcct tggcgaccat gacctgggcg gataccaggg
     1921 cctttccgat ggccagaggc ctcttgtgcg tcatatcccg tatccacacc atgtcccctt
     1981 cctttatgtc cggatcgacc tccactatcc ccggccccat gacgtccgcg ccgttggtca
     2041 cgtaaggcac ggctcccatg tccacggaca cgaatccctt ggtggccttg tgcttcaaca
     2101 gtccgcgtat ggtcgggaac ggacggccgt cgaccatcat gccctcgatt acgttgttga
     2161 tgattatcag ctcgcattcc gggccctcgg cggtgtccac ggtgtccttg gggccgatga
     2221 tatccacgcc agtggccgct cgcaacgcat cgaccagtgc cttgagctcc ttctctcgaa
     2281 gcctcttgcg cttcctcacc ctgatctcgc tcacgcccca ccctatgttt tcggcgtcaa
     2341 ttaactttgc gccctgatcg gctccttggg actggccgtg gcatatcttc ataaatcacc
     2401 atgtcactgc tttccttcat gaagttgccc ctggtggcca ctcgcttgat aataatcgcg
     2461 ttcaagctga tggtggtggc gatagttgtg ctcagtattg taccgctcct caccggcggc
     2521 ataggcctcg acctggacgg tgcggacaac gctgatatga ccatggatga cggcaccatc
     2581 cggatcgata tgccgataac tgttcgcaac gagggtttct ttgacataaa cgatctccag
     2641 gtctccttca ccttcatgga tgagaacggg acattactgg cagagagcga gggcgagcag
     2701 gtcgacatac ctgtgggagg ggagaccgag gtgcccatcg cgcttgaatt ggacctgtat
     2761 gacctggacc ggccgacccg ctcggacctg atattcaacg gcaccgatct gaagttcgac
     2821 gtgaaggtgt ccgccaagta caccatggac ctggtcaagc tcagcgtgga ggcgggcagt
     2881 gacatgagct gggggccgtt cgtcaacgac ctgcaggtac aggagtggaa cgcccaggtc
     2941 accgacgaag gcgatgaaca gttcgtgagc gtaccgttct ccttccgggc tgacgatgca
     3001 ttcaatggac ttcaagcggt caccgtcacc gattaccggg acggcaatta caccagcaac
     3061 gtgacccaga cggtccacat gtcgtcacag gtcaacgaga tggcgaagat acccatttcc
     3121 caggaggcct acgaccgttt gatgtccggc accgccaacg ccaccgttcg caccaccctg
     3181 tacgtgttcg attgctcgac ctatgacgat ggtaatctga acatgggagg aggtggggga
     3241 ggtggtggcg gtggcatagg ccaacctgtg aaggacctgc aaccccagat ggccggctcg
     3301 ttcctggctt ttgatggtct caactataac gtggtcgtcc cttacagtta caacacaagt
     3361 cccgcctacc aggggcagga agcacatatg ctgatcgagt attgggacga ttatggattc
     3421 aatgtcagca tctggcaaac ggtctatctg tgggacaata gctggcagca ggtttggtta
     3481 cctctatccc cagaagcgta cgatcatgtg accaacggaa atgaagtggt ccatgtcagg
     3541 gtcaccgcat tcccgtggat catcctggcc gagcaaacct acagcgaacc atggggggcg
     3601 ggcccgtgaa catcggtgag ttcgacaaga agtacttttc cttccccaag ggagccgtca
     3661 ccgccacggt gcacgccctg aagtacctgg cgatcccgta cgttctgttc accgtcgggt
     3721 tgatcgtcct caccggccag gacggaccgc agcgggtggc cgacctgctg atcgagctcc
     3781 agaccgtggg gctcatcttc ggtatagtgc tgacggcact agggttcttc aagggagcgt
     3841 atcccaaggg cagctactcc cgcttcctgt tcggcctcac cgcctccgtg ctggtgatcg
     3901 tgtacgtatt ctctatgctg ctgcaaggcc gtgtccagga cgtcatagcc aaggaagcgt
     3961 tcgaactgga cctgtacctg atcttcaccc tgtacttcat tccggcgatc ctggcggtgc
     4021 tcatgcagtt cggcgagttc gccgaccacc gccgcccgtt cctggagaag gaaggtaagc
     4081 tccaggtcaa ggagaaggag gacccccagg accatcgctt ctaccatgac ttccggatcc
     4141 gctacggttc actgttcaac gggctgaagc tgggccggag caccctgacc gggttcgtgc
     4201 tccttcctat ggtggtcata atcattctga aggcgggaat gtcctccctg gacgttcagg
     4261 aggtggattc cgcgctgtcc aagttggatg acgtgtcctc gctcttgatc atgctgggtg
     4321 tccccatggc cgccctggcc ttcttcaagg ggttctaccc caaaggctcg ttctcccgct
     4381 tcctgccatc cgtcatcatg gtattgatca gcctgtactg gatatggact gtgggtctgg
     4441 gagggaagtt cgtcttcgac gccatcgagg acgtatcgat cgacctggac ttctccaagc
     4501 tgctactgct cctgatggtc ggtaccgggc tgtggatcgt ctactacgca ttggaactgc
     4561 tgctctaccg cccggagtgg aagaagggcg gttttcccaa ggacctgctc gaagagcgca
     4621 aggcccgcaa ggaggcccag cgtaaagcga aagaggaacg gaaggcggcc aaggaaaagg
     4681 cgaaggaaga caagaaggcg gccaaggaga agaagaaagc cgacgcggaa acgccgactc
     4741 aggacggcaa ggagccgtag aactccatta tctgggacat cacggtgtcc ggatgataac
     4801 ggccgagcac ctcccgaccg gccctggcgg tgatctggca cagctcgtca tcatctagca
     4861 gaagctgaag cttcttggcc aggtccgagt ggtccccgtt cccgaaggat agggccgcct
     4921 cgcccaatat ggtcgcggac gatccgctat ccgagaccag catcggcagg ccgtgggaca
     4981 acgcttccaa aatcgtccgg ggaaaaggtt ccggccagag ggctggatgc acgaagatgt
     5041 cggccatcgc atagtaccgt ccgatctcct ccttttccat gaacccggtg aatatcacct
     5101 tgccttccag acccagctcg tcgaccagct tcttcagctg ctgttcgtag ccgcccttgc
     5161 ccactatgta cagaacgctg ccctcgttga gcagggcgaa ggcccttatc aacacctgga
     5221 gacctttctc cgcctccaac ctgcccacgt atagtatgac cttgttgtgc cccgcgttgg
     5281 taggccttga aggaccagtg cacaatccgg gatcgaacat attgggtatg agcttgatca
     5341 gctgggggtc gtaaccagcg tctaaatagc attggcgagt cgattccgac aacgcgatgt
     5401 agccgttcgc acttcgcgag agccggtgca gccagatgaa ctgcacccag tgataaggca
     5461 tcaacatccg cctccacagc ggacccgggc ggcgcacggc gcaggccagg gaatccagtg
     5521 gtcgacaggt cgcgcattcc ccctccacat acatacttgg attggtgcac accggtgcca
     5581 gattgttcag ggttgcggtg accctcttgt tcatcttttt tccatacttg acggccgctg
     5641 gaagctgctg ggtgttgtag acatggatga tgtcacaatc gggagcgcgc ctcctcagct
     5701 cgccgtaagc cagacggttc agtccgccga gggtggggga ggtgcggaag aataaggtgt
     5761 cgcccatctc accgctcact cccggggaag gatcgccgtt gaatacccac acgtcggtgt
     5821 gcacgccgcg ggaacgcagc ccctccacca acagctggca gctgaaagcg caccctccgg
     5881 tgtaacgtgg aggatagtca ggggtgatca ccaggacacg gaaaggggca ggggtcgaga
     5941 gcagcggaac acctatgaga gggcaatatc aatcccatta ggtaatgttt ttccccatcc
     6001 tggagcgcaa gacggcaccg agggggatta aataattcca tcgccttgtt gtggacggtc
     6061 tttcgaatga aggtatccat catcggcacg gggtatgttg gactggtctc tggagtatgc
     6121 ttcgccgagc tcgggcacca tgtggtttgc gtcgataatg tcgtggagaa ggtgcgcaga
     6181 attaacgagg gcgtgccgcc catattcgag gaaggtctgg aagagatgct cggccggcac
     6241 ctggcatccg gttcgttccg ggccactaac gattactcgg aggttccgga cacggatatc
     6301 actttcctgt gcgtgggcac cccatcccac gaggatggca ccctggacct gagatacctg
     6361 ctcaaggcga cggaggacct gggcaaggcc ctatcgaaaa agaaggaacg gcacactgtg
     6421 gtggtaaaga gcaccgttcc tcccaacacc accagggacg tggtcggacc tttgctgctc
     6481 aagacctccg gaagaacggc ggaagaactg ggactggcca tgaacccgga gttcctcaag
     6541 gagggaatgg cggtcaagga cttcctgaac cctgaccgag tggtcatcgg ggcttcggac
     6601 gatcggacgt acgaggaggt ggcctccctt tacgatagga tagaggctcc gctcttgcgc
     6661 accgacacct ccacggcgga gatggtcaag atggcttcga acgccttttt ggccgcccgg
     6721 atctccctgg tcaacgagct cggcaatcta tgcaagtcat tgggactgga cttccgagag
     6781 gtggccaagg gcgtaggcat ggacccccgc gtgggacctc tgttcctgaa ggccggctgc
     6841 ggcttcggcg gctcctgctt tcccaaggac gtccggtcga taagggcgca ggcgcgttcc
     6901 cttggtgttc gaacggacat gctggacgcc acgctctccg ttaacgaacg gcaacccagg
     6961 cggatcatag agctgctgga gaggaggacc gaggtgtacg gaagcacggt ggccgttctg
     7021 ggcctggcct tcaaaccggg caccgacgat atccgcgaag ccagctcgct gacggtggtg
     7081 gccgagctgc tccgcaaggg cgcaacggtc agagcgtacg acccacaggc catggacaac
     7141 ttcaaacggg agtttcccca gatcttatac tgccattcgg ccaaggagtg cctcaagggc
     7201 gccgataccg ctctcatctt gacagaatgg caggagttct cggacccctc gctatacggg
     7261 agcatgctgg tggtggacgg ccggggcgta acaaaaacca ataactatga agggatatgc
     7321 tggtagtcat gaaggcggtc attccagcgg ctggatgggg ggtcaggttc ctcccgctga
     7381 ccaaggagca gcccaaggag atgctcccgg tcatcgacaa gccagtcatc cagtatgtgg
     7441 tcgaagaagc ggttaaggcc ggaataaggg acataatcat cgtcaccggc cgtcacaagc
     7501 ggaccatcga ggaccacttc gaccgttcct tcgagctgga gagcatactc aagaacggca
     7561 accgtccggc gcttctggag agcattaacc gcctgcatga cctggccgat ctccattata
     7621 tacgccagca cgaacagcgc ggccttggcg acgcggtcta ccaggcaagg catcatgtcg
     7681 ggaacgagcc gttcgcggtc atgctcgggg acaccatcca cgtctccgag gtaccagtgg
     7741 tcaagcagct tatggaggtg cacgcccgca ccggcaaatc ggtcattgcc gcggagcgcg
     7801 taccagggga caaagtaaag gactacggcg tcctggacgc gaaaaagatc gatgaccgcc
     7861 tctacgagat caacgatctg gtcgagaagc ccaggccaga ggaggccccc tccgacctgt
     7921 gcatcgccgg cacttacgtg ctaactccgg gaatattcga atgcctggag cacacgccgc
     7981 ccggtcacaa cggggaggtg cagctcaccg acgcgctgcg cctactgcag aagaaggagg
     8041 gtatgctggc ctgggagttc gtcgggaaac gttatgacat cggcgacatc ccgggatggc
     8101 tagactcgca gttcgagctt gcgcttaggc atcctgtcta cggcgaaaag ctcaggaaac
     8161 gcatccggga gctgaacgag aaggagcatt tcctctgatc atgtaggaat cagaaggagc
     8221 ggcctggttg agccttttat cacttcttcc gaagtggaac cgagcgtcgc ccctcgcagg
     8281 tagccttttc cggtcgttcc gagaacgatg agcgtggcgt cgatctcccg cgtcgcctcc
     8341 aggatgttat aggtcgtggt cccgaaatgg aggtggacgt cgatctcgca atccttggcg
     8401 tccagcttgg actggaacgt ctccatcttc tgctttacct cctggaagcg cttgtcgtcg
     8461 gtcatgttgt acttggccga ctggacgaca tggaacaggg tcatcttcct cgccccggcg
     8521 tcgatgagct gttgtacctg agggagcatg gccttggagg ccttgctcag gtctatggtg
     8581 accaacaccc ggtcgagcag gggagggctc ttctcacgat agccccgagg gtcgtcactt
     8641 gcctctaatg gaaacttgtt caaaagaacg ggaagcttgg aacgacgtat gacctctaag
     8701 gacgtgcttc cgacgatgaa ctccttaacc ctgccttttc cggaagcggc catggcgatc
     8761 atggtggcgc cgtgcgattc agcggccttg agtatggccg gggctggctc cttacggacc
     8821 tcggtgacca gttcgtggct gagaccggcc tcgccgatgc tctcgtccag agctttcagc
     8881 aacgggtccc gtttggagac gtgatcgagg gcggaataga tcatgacctc cttcacgccg
     8941 taaccttcca tgcgggtggc gatatcgacc atcatcatgg actgcggaga taggtccacc
     9001 gggaccaaga gcttcttgaa catgatacga tacagtaacc cagagactag gatattaggt
     9061 ttattccact tttaatggaa cgacattttc agtaacttcc ccgtaacctt gatgtccggg
     9121 tacctcttca ccgaaaggct ggaacgccaa gatgaccgcc gcctttgacc aagcagccga
     9181 ccgaaggacc ggagcagtac tcaccaccct cctctccagc ctgatgcttg gatcgtcata
     9241 cgtggcggtc aagatgacgg tcggcgacgt gaaccccttc ttgctggggg cggcgaccat
     9301 ggccatcggt tcggtcgttc ttctggtcta tatggccatc aggggcaagc tgaaccggac
     9361 catgttgaag cgctgggagt tctgggtcgg tccgatcatc aacaccggag tggtggcccc
     9421 atcctatgtt ggattgacca tgaccaccgc ttccgcggcc gggctgatca taggcaccaa
     9481 cgtggtgttc gtggcacttt tcagccgcat cctgttcgga gagcgattgg gcaagcggcg
     9541 cttgttggga ctggggatcg ccttgctggg cttgatcacc ctcaccaccc gctggaacct
     9601 gtcgctgctg gacggctctc agatgaccgg aaacctcctg gtattgatct catcgatctg
     9661 catcggggtg tccgtggtca cttccaggat agccttgcgt gaactgaccg cggagcagtg
     9721 gagcctgagc ctgcacctac tattgccgcc ggcgctgtta gcattgttct tcatcgtgcc
     9781 tatggacggc ggtctatcct cgacgaacct tcccgcggcg ctcttcattg gcatagtgtg
     9841 caccacgctg cccacggtgc tatggacctc ggccctgaag cacataagcg tggtcacctc
     9901 ggccaccatc ctgatggtgg aatccgcctt cgccgtgttc ctgagctgga tattcctagg
     9961 ggagttgatc gatatctacg tgatcaccgg cgcgatgatg atattcgccg ccatactgct
    10021 catggccagg tcagaatgaa tagccagaac accggcggag ctcattagaa tagaagaagg
    10081 ttaaaaggtt tggatctatg gaacggacag gaagattact tcttcttgtc ttccttcttc
    10141 ttctcaccct tgggaccgca ctttccgcag gacatgctcg acctcctatg gggagaccca
    10201 cgaaaacgaa attgtagcgg tccgtatatt aagttaatct tgccagtaaa ataaatgtta
    10261 aaaaaatatg tgcttaataa caccgctctg gatatcttgt tacggcctgt tcaccaaaaa
    10321 tgaatatttt cgttcttacc ttgaccgata aatcctccat gataatcgtt cagcgaaaac
    10381 atactggcag tacattatta tcaaaaatca aaactgattc tgtgacgatt cgatttaaat
    10441 atcgtccttg acgctaggag atttcgtggt aaagatgcac gttttggaga catctaaact
    10501 gctgaccgag gaatataccg ccaagatcct gatggccacc atggggcggg ctaaaagcgc
    10561 gttcgagctc agcgatgccc tggggatccc catcgccgcc tgttatcgca agataagggt
    10621 gctcgaggat gccggtctga tacgttgcag cgagaggcgc ctaacccagt cgggaaagcg
    10681 catgagcatg tacaagtcga tggtccgcaa tgccaatatc acgttcgagc gcaacaagat
    10741 ccgcgcccgt atcgagatgg aggacgggag cagcaccgat gactgcttgg acatcgacct
    10801 gggaatgatg ttcaaggagt cccacgcctg atcggccggc ctccactctt tttccttcct
    10861 attttattcc tacagtaatc ctatgattcc agttgggaat cgcatcacct aataatatcg
    10921 acaattccag taggattcgt gggaaattat aattaattcc gctcgtgcta tgcgtttttc
    10981 acaatcttta ttaatcatct tacggaagag ggcatggcga tttgcccata tccggcaatt
    11041 tccagcatgg ggaggaagtg gataatgagc gacggaaaga ccatcgagag cgttatggag
    11101 gaggtgcggc gtttcccgcc ctcgaaggag ttcagccagc aggcccatat aaagagcctt
    11161 gagcagtacc agaagatgta caaggaatcg gtcgccgacc cggaaggatt ctgggccaag
    11221 atggcctccg aggaactgca ctggttcgcc aagtggaaca aggtccacag ctgggacaag
    11281 gagaacgcca tcatcaagtg gttcgaagga ggaaagctga acgtctccta caactgcctt
    11341 gaccgccaca tagagaacgg ccgcaagaac aaggcggcaa tcatctggca gggcgagaac
    11401 gaggatgatg ttaggacctt gacctatcag cagctgcata ccgaggtctg ccgcttcgcc
    11461 aacgttctga agtccaacgg ggtaaagaag ggcgatcggg tctccatgta catgccgatg
    11521 atacctgagc tggccatagc catgctggcc tgcacgcgca tcggagcggt tcatagcatc
    11581 gtcttcggtg gcttcagctc cgagtcgctg aaggaccgca tcgccgattg cgggtccaag
    11641 gtcctggtca ccgccgatgg aaaccaccgc ggcagcaagt tcgtaccgct gaaggccaac
    11701 tgcgacgatg ccctggacaa gggcacatcg gtggaaaagg tgatcgtggt caagcgcgcc
    11761 ggcgccgaat gctccatgga gcccggaagg gacgtatggt ggcatgacga gatggtcaag
    11821 gccgaccgtt cctgcgagcc ggtctggtgc gatgcggagg acccgctctt cattctctac
    11881 acctcgggat ccaccggaaa gccgaaggga gtcgtgcaca gtaccgccgg ctatctgctc
    11941 ggggcctcgg tcagcttcaa gtacatcttc gattaccatg aggatgacac ctattggtgc
    12001 actgccgatc tgggctggat caccggtcac agctacataa tctacggacc gctgtgctcc
    12061 ggcgccacca cgctgatgtt cgaaggcata ccgacctatc cgcaggtgga ccgcttctgg
    12121 aacatcgtgg agaagttcaa ggtgaacatc ttctacaccg cgccgaccgc catccgctcc
    12181 ctgatgaggg agggagagaa gtggcctcaa ggcagggacc tcagctcgct tcgcgttctc
    12241 ggctcagtag gcgaacccat caacccggag gcgtggatgt ggtatcacaa gtacgtcggc
    12301 aacgagaaat gcccgataat ggacacctgg tggcagacgg agacgggttc catcctgatc
    12361 accccgctgc ccggggccat aaccaccaag cccggttcgg cgacgctgcc gttcttcggg
    12421 gtagccccgg tgatcgtcaa ggatgacggc accccggccg gcgtgaacga aggcggatac
    12481 ctgtgcataa gcaagccctg gccgtccatc atgcggacgg tatggggaga gcatcagagg
    12541 ttcaaagaga cctattgggt ccgattcccc ggtaagtatt tcacggggga ttccgcgcgc
    12601 tgtgacaacg agggttacta ctggatcatg ggccgggtgg atgacgtcat caaggtatcc
    12661 ggccaccgca taggagcggc cgaggtggag tccgcgctgg tctcccatca cgatgtggcc
    12721 gaggcggcca tcgttcccgt gccgcatgcc atcaagggag aggccatcta cgccttcgtg
    12781 accctgaaga acggcgtggt ggaaacggaa cagctgcgca aggagctggt ggctcacgtt
    12841 cgaaaggagg tgggtccgat cgccaccccg gaggtcatac agttctgccc cggaatgccg
    12901 aagacccgtt cgggcaagat catgcgccgc atcctgcgca aggtcgctac cggcaccgcc
    12961 gaggagctgg gggacacctc tacgctagcc gaccccggga tactggacgt tctgatccag
    13021 ggttcccgcg ccctgcataa gaagtaggcc taaacccctt ttttaaaaac ctttctattt
    13081 tactttccct ttagctctcc accgacgtag gagaacatct tcttgacgtt gatcagatcg
    13141 aggaaatatt tcacatccat tcgggtgaac tccttgagcg cggccaggac caataggaac
    13201 gcggcgtagg ccaccagacc gaagatgatc agagtgtaga agcggtctat tgatatgaac
    13261 aggtcgagga cgaacatggc tccggcggcc gccagaccgg ctagcaactg atatgccagc
    13321 ctgacgttcg gaaccgtgcc ggtcaaccgg taaacggaat atcgcaccat cagtaaggag
    13381 acgaagttac cgatgagcag cgccagggcc gccccgacga aagataggcc gaggccgaag
    13441 cccggtatga acagtaacat cagagagatg ttcatgatga ctgtgactat agtgatccgg
    13501 gccgagatgt ccggacggcc aacggcgact atctgagagc tatgcacggc gttgatcatg
    13561 gtgatgaagg tggtggcgac cattatgccg atggccctcc cggaatcgat gtacttcggt
    13621 cccagcagca cctcgcagac ctcgtagggg aacatcatta tgagaatggt caccggcagc
    13681 ccgatcatgg ctatgtagcg ctccgcctgc ttggacaatg acctgatctc caccaggttg
    13741 ccatccttgt gcagcttcga gaaggaaggg aacgttagag tggaaacggc cgtactgatg
    13801 gtcgcgaaga cccccaggaa caccgcgggt gctgcgtaca gtccaacgtc ggtgggattc
    13861 cagaagaagg ttatgagcag tttgtcggcg ctcccactga ccgcgctgat gacggttatg
    13921 attatcagag gcagggcgaa ggtgtaatag gaacgaagga gcactggccg cgtccacttt
    13981 atcctttctc ggaggagcat gtacatggag acgacgaaga ccactgccga tcctaccaga
    14041 tacgacaatg tcagttccat gacgcccatg tagtttagcg cgacgaaaat aaccagggga
    14101 accctgacca gaggttcgac gagagtggcc aggggcatct tggccatctc catgcgggcc
    14161 tggaaggtga cggtggctat gctagagagg tcatagagca cctggtatag gatgaataga
    14221 aagattatct gcatgctggt gccagacagt acgtttccca tcaccgtcgt ccacacgaat
    14281 atggacacca tggtgatcaa gaccatcagt ccggtcagga ccaccttgat gaaggcgaag
    14341 gtgctgatgc attggttcgg atcggcccct tcggagacac gtttgatgtg ggcgctgctg
    14401 aatcccaggt cggacacggc gttgaaggtg gccaccaggg ccatggccgc ggtgaccgtt
    14461 ccatagatgt ccgtctccag atatctggtg atgaaataca gcccgacata ggccagggct
    14521 gcggatatca tcttcgaaag gaaaaggatg aacgaccttc ggcctagcac gtgatcgcct
    14581 ggaaacatgc gccttgatat ttaactgtgc ttcgcttcac tcttcctccc acttggtgat
    14641 cagcaccgct acgatcacga atatcacacc gatgacggcc accaccgcca gattgaagta
    14701 ggcgtcggcg aggttgtcat agaccatggc gtccctcagc ccctggctca tgtaggtgag
    14761 cggcagcacc ttcgctatct gctgcaggta ggagggcatc atctccagct ggaagaaggt
    14821 cccggacaga aacatcatcg ggaaggtgat ggcgttcgcg gccatgctgg ccgtctcctc
    14881 gttcttaacg aatcgggcga cgatcatgcc cagggcggag aacatggcgc tcccggcgat
    14941 tatcatcagg accaccacca ggttgacgct catgctcatt ccgaatatga gcatgccaaa
    15001 gcccatgatc accgccaggg tgaggaagga gatgaagagg tgccacagga tgcgggacag
    15061 cagccattcg aaaggcgtca tgggggtcgt ggccagctta cggaatatcc cgttcgcccg
    15121 gaagcgggat atggtgcctt ggacgttgaa cacgcaggtg gtcatgatcg tcaggccgat
    15181 gataccaggc acaaagaagt ccaggaaggt gaatcgcttc tgcactatgc tgccgacctc
    15241 gatgacgatg tactgatcac cgccggccat atacaggttc atagcgttga ccaccccgtt
    15301 caccgcattg aacaccgttc cggaggtgga caccgtctcg tccagacgca gctccaccgt
    15361 agccgtgacg ttactggcca gattactgga gtaattggct gggatcacca tcacatacgc
    15421 caacgagttg tcctttacat actggtccag atcggtcgac ggggaaatga acttgagctt
    15481 gaccatgccg gtctcgttaa gagcggccag catctgctgc gacccaggac cttcgtccag
    15541 gttctgcacg ttcagggtca ccgcttccga ccccatgttc gagaagatgg ccccgaatat
    15601 cactatcaac agcagaggga aggcgaacac ccagaacagg ttgctcttga tgcgaaagaa
    15661 cgatcgagcc tggcccttga ggtccaccag gacgtgcttc ggcctcattg ctcgacctcc
    15721 accagtttct tcccggtgag cttgaggaag acgtcctcca gagaggagcc tttgatgagc
    15781 acctcgtcgt aggtgacctc ggacgatgac agtaggccga tgagcttggc cagcgaacct
    15841 ttgttgtcca tccttaccag caggtcgccg tggttcgatt cgaacgccat gcccgcggac
    15901 cgcacggctt ccgtggccgc ggcgttggca cctttaacaa tgcaggtgct tccggaacca
    15961 tactggtcaa ctatctgttt tggtgtgccc atggcgatga acctgccgtc gttcatgatg
    16021 gccacgtggt ccgagagtac ctccgcctcc tccatgtaat gggtggtgag tatcacggtc
    16081 ttgttctggg acttgagctt ccgtatgacc tcccagactt ctctccgggc cttgggatcg
    16141 agaccggtgg tcggctcgtc caggaatacc aggtcagggt cgttgaccat ggcgatggcc
    16201 actcccaccc tctgtttgag accgccggaa agattggtga accatacgtt gcgcttgtct
    16261 tgcagctgca ccgcttcgat cagttcgtca gtggcgatac gcttctcgaa cagaccgccg
    16321 aaatattcga tgttctcctt gaccgtcaga taatcgaagg cgttgaacga ttgcgggagg
    16381 acacctattc tcttcttgat ctccctttga cctttctgga tatcgtggcc gagtatgcgc
    16441 acctctcccg aggtcttctt acgcaggcat tccatgatct ccaccgaagt ggtcttcccg
    16501 gcgccgttcg gccccaatat ggaacagacc tccccggcct tcacgtccag atctatgccg
    16561 ttcacggcga tcaggtcgcc gtatcttttt acgaggcccc ttacctcgat gaccgtctcc
    16621 accaatagcc cccataatga gggaggaaat ttttatttat atatcttgtc tcacgaaata
    16681 tttttaaact aatcgcggag ggagcacctg ttatattcgc cgatgccctt ccttgcccgt
    16741 atgaaagacc gttacgctcg ccagttatcc attcccggct tcgggcctca ggcccagaag
    16801 aagctttccg aggcgagcgt ggccgtggtc ggcgtgggcg gtctgggctc accggtgtgc
    16861 caatacctgg ccgcggcggg ggtcggcaag ctgatactca tagacgacca gaaggccgag
    16921 ccgtccaacc tgaaccgcca ggtcatacac ttcgaggagg acgcccttct ccctcgctac
    16981 aaggtggaat cggcgcgcct gaaattggaa gcgttcaatt cggacatcga cgtggaggcg
    17041 ttgccgatga agctggagga ggagacctcg ttcatnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17161 nnnnnnnnnn nnnnnctggc agatcgacga ggtggtcttc acccgtaacc cctcctgccc
    17221 ggactgcggc tcacttcgac cataggtcga tggtgaccag ataggtatcc tccatcagcc
    17281 tggtctccac cttcagccca gttcggtaga acaggtcgag catgcgcatg ttctctccga
    17341 gcagctcggc ggtgaaggcc ttgatcttgc ggtcccgggc gatggcgatc attatgtcca
    17401 tgagcatggt cccgatgcgc ttgttctgcc atttatcgct aaccgcgaac gagatctcgg
    17461 cggtgttgga cgctttatcg agatcgtaca tggcgaagga ggtcatggac caaacctcat
    17521 cctcgatcac gaaaccgcag acggtcaccc tggtatcgta atcgatgttc acgattcgca
    17581 tcagctcgcg gtggggcatg ctgcgcttga ggcccatgaa ccggttgtag accgtgtccc
    17641 tggacaatga atagaacatc tccttgagca tcggctcgtc cgtaggtttc gcagggcgga
    17701 agtacatctc ctggtcggcc accacgcgca cggactcgta ctgctccgga tatatcccaa
    17761 cgtagccggc ctccatctgg tcctggtata cgtaatgcag tgacttggcg ttcatcagca
    17821 gctcggcccg gaagcgcggg tgcgaaatgc cgatcagcga cagcgagcgt tccatgatgc
    17881 tcttcccgcg caggtcggcc accccgaact cggttaccac gaactgcacg tcaccccgcg
    17941 tcgtcgtcac gccccctccg gccgatagcg tgggaacgat gcgcgagatg gtatgatgct
    18001 gggcggtgga cggcatggcg attatggcct tgccgccggg ggaacgcgcc gcccctcgca
    18061 tgaagtcggc ctgaccgccg atgccggaat agaaccgatg gccgatctgg tcggtgcaca
    18121 cctgaccggt gaggtccacc tccagtgcgg agtttatggc gatcatgttg ttgttgcggg
    18181 agatgttgca cggatcgttg gtgtacgagg acgggtacat ctcgaacatc tcgttcccgt
    18241 ctatgaaatc gtagagacgt ttggagccca tgcagaagga agagacgacc ttgccgtcgt
    18301 ggaatccctt cctcctcccg gtgatgacgc ccttttccac caggtcgatg atgccatcgg
    18361 agaacatctc ggtgtgcacg cccaggtcct tcttctcgtc caggtacgcc aggatggcgt
    18421 ccgggacgtt gccatagcct atctgtatcg tcgccccgtc cggaatgagc tcggccacgt
    18481 tcttccctat gcgcggcgcg gtgcgggaga cctccccttc cccgacgaac tccaggatcg
    18541 gctggtcgtt ctccacgaag tggtctatct ccctcatgtg caaacggctg ttcccgccca
    18601 ggcgaggcat gttgggattg acctccgcta tgaccacgtc agcgtgcatg gccgcggaca
    18661 tggtgatgtc gaccgacacg ccgagattgc aatatccatc gtcatccggc ggtgatacct
    18721 ggatcaacgc cacgtccact ggcttcagac cgctggagaa aaggcgttcg atatcggaca
    18781 ggttgaccgg agtgtaatcc gccttcccct cgttcaccgc cccccgcacg ttgggaccga
    18841 tgaagaaggc gttgagccgg aactggtccc ggaactggtc ctcggcgtag aacgtcaggc
    18901 ctaacgacag agtctgtatg acctcgctat cgatcatggc ataggatttg gctagcagcg
    18961 ctttcactag cgcctgcggc tccccgcagg ccgttcccag gaacaccgtc cttcctggac
    19021 ctatcttcag caccgcctcc tcggcggtga ggatctttga ccggtactcc ttctcccaat
    19081 ccctgcccat tgacctcact tatcggcaat cgtgccatta aatgcttctg cgtcgaaccg
    19141 agggaacgac gcaaattact tgaccgacaa tcgtaatgga cgggcgatga tcatcgagct
    19201 ttggatactg gcggtgttcc tggtgctcat tggcatcctg gttcttgtca tagtggttag
    19261 cagcctgatc aagttcttca ccgccatcgt agcggccatc ttcgtactga tgttcaccgg
    19321 gagcggtcta ctggccggag cggccttcct ggtcgtggcc atcatcgtgg ccgtggctag
    19381 attagcaaat ccttatctcc gtcgatagcc atgttggatg gggtttcctc aatggaacta
    19441 agcagcgtgg acaagaagag ggtcatcagc aaggacggtc gcgagctcgg cgtcctgtat
    19501 ggcagcacca tagataccgg caagtggacg gtcctgcata tcctggtcaa tgtgagcaag
    19561 gacgcggcca aggagctgca cataaagaag aagctcttca aaccgatcat catcaacgtc
    19621 tccaccgacc tggtggcggt ggtgggcgat gttatacagt tacgctcgac catgaaggag
    19681 cttgacgagc tgttctaaac acgttcgtta tcgaagcgcg gccttccgca tctccagcat
    19741 tttgcatcgc gggagatgtt gacggcgtcg cattcgcagg tccaggtgcc tttgagatcg
    19801 aacgattcgc acactgtgca cttggacttg ccctccctgg gcttggcctc aaccatcgtg
    19861 aactgctctt gagctgccgc tagataaggg ttttggcctc tggtcagcgg tccacgccct
    19921 tcctggaggt gatccccttt tggtaggggt gcctcaccgc ctcgacctcg ctgatatagt
    19981 cagccatatc aagcagttcc ggcggcgcgt gacgaccggt gatcaccgcc tcgacccctt
    20041 gatggcgccc ccctatcgcc ttgaccacct cattgacgtt caccaacccg aacttgatgg
    20101 ccacgctcac ctcgtccagc accactatcc tgtatcttcc cgatctcagc gcctcggccg
    20161 ccagttccag gccctcggcc gccctgtcca ggtcggcctg ggttatatct ttggaaaaga
    20221 ccaggcagtc attgccggac gccactacat ccaatccagg cagatcaagg aagttctccc
    20281 cgtaggtacc ggcggtcttc atgaactgga cgatgagcgc gcggtagccg tggcccaccg
    20341 ctcggacgca catgcccaac gcagccgtgg tcttcccctt gccgtcgccg gtgtatacgt
    20401 ggaccagtcc gatgtcgtcc atctcagtcc agcttcttga gcagccaggc catgttctgc
    20461 cccagggtct tcatggtcct gatgccttcc tcgtccatgg cgatgtcgcc tggtttcagg
    20521 gcggtgatgg tgttccagta actgcttccg ggcacgatca tctggctgat gaggaatagt
    20581 ttgttaatct catcgaaagt gtcaagcgct ccggcgcggc ggttcaccgc cacggccgcc
    20641 ccgaccttcc ggcggaacat gtcgccattg gcccgggcga cgtagaaggc ccggtccagg
    20701 aaagccttcg tttgagcggt catgttgccg aagtacactg gcgagccgat tatcatcccg
    20761 tcggccgcct tcattttctg tacgtactcg ttcagacggt cctcggccat gacgcacctc
    20821 tggtccttat tcttaccgca ggaaccgcag gcccggcagg gcttgatatc ttcccggcat
    20881 atgtcaatca gctcggtatc gaaaccttcg ttcttcagtt cctgtagaac gaactctaag
    20941 gcctgatggg tgttgccgtt gacccttgga cttccgttga acgccactac tttcatgata
    21001 tctccgacat cccaatactg cccacgatat tatcgttttt ctttttttcc gatcaccaat
    21061 gctttctttt atccgtcagc ccttgaaggg agaggcgacc atgggagcgt tctgggaggg
    21121 gttgatagct ggatatggta tcgctattcc cctgggggcg gtgtccattc tcatagtcaa
    21181 caccgctctc gaccgagggt tccggctagg cctcgtggcc ggagcgggaa ccgcgacggt
    21241 ggacctatta tgcgccgcct tagccgtatt cgccgggacg gcggcggtgg ctttcatcgc
    21301 gccctattcc ggaccgttgc aagtggcgag cgggatcgcg ctcatcgcca tgggcgtata
    21361 tggcatccta cggttacgga gaagggtgaa ggatagcgtt ccagataccg ggaaccagga
    21421 cggagagatc accgtctacg gtaagttcgt ggccctgaca ttgcttaacc ccttcaccgt
    21481 agcctatttc ttggcgctga tccttggaaa aggagcgagc tggtcattct cattcgggga
    21541 ctgtctgtgg ttcatcgctg gggtcggcct ggcatcgcta tcctgggaaa ctctgctcgc
    21601 cgccgtcgga gcattggccc ggaagcacct tacaccccgg ttcatgaccg ccagcatttt
    21661 gatcggcaac agcatcgtca tccttctcgg gttacgaata atgatggcgc tgtgatcgtt
    21721 cacgaccggt tcgtaggcac caggctaaaa aacattaact atttattcgt cctgattcaa
    21781 tgcgtattac taaaaaatga ttcgtaacac gaaatcatta gtaatttgtt actgggggaa
    21841 gttaacacgc acattcctga tggactcatg gacccggtgg tggtgggatt gggctgggcc
    21901 atcgccttgc ccttcatcgc cctggcagtt tataaattga ataagaaagt tgacgagagg
    21961 atggtcccct tcatggccat cttggctgcc ggcatattcg ttgctcaaat gctgaacttc
    22021 cccgtcgggg gaggaaccac tggacatctg gtgggagcgg ccctggcagt gatcctcctc
    22081 ggcctctacg ggggcattct ggtattgacc acaatactgg tcatccaatg cctggtattc
    22141 ggtgatggag gcctaaccgc cctgggactt aacctgctca acatggcggt catcgcacct
    22201 ctggtgtcat acggagtgct caggttgctg aagaagcacc aatcattggc tgtgccgttg
    22261 gccgcctggg cctcggtctt cctggcagca ctcgcctgcg gccttctgct ggcattgagc
    22321 tacaccatat ccggagggga tttcggaata gtcgcctcgg tctcgatccc ggcgatggct
    22381 ggatggcacg ccataatcgc cattggcgaa gcgctcataa ccacaggggt agtagtgttc
    22441 atcagccggg tagccccgga gatgctggag atgggaaaga accaggaagt caaggaggcg
    22501 gtcgtttgaa ctggaagagc tatggcaagg caacggcggt gatactggtc ctattcgcca
    22561 taggcctggt cggttatttc gccttctccg cggcctttcc ggacggtctg gagaaggtca
    22621 tggaggataa ccacgtggaa gaggctgaac aggtttggac cgctcccctc agctatggcg
    22681 agaactgggc cggagcgctc atcgccggtc tcatcggttt cgccttgacc tttttgctgg
    22741 tgttcctgta cttgaaaggg atgcggtccc gccagaaggc ataataaacc atttactcca
    22801 ttcttatttt tcacagattc gtaacacccg ggattcatta tgcaaaaaca tgccgacggc
    22861 cacgctcgcg attccgcctt gtcacgcttc gatccccggg tcaagctggt ctgcatcttc
    22921 gcattggtgg tgctgatctc aacgttcacc gaccggaatg cgttggtcct cgccttgatt
    22981 ttcaccatcg tcctgatgtt actttcccga gtatcgatga cccacctgtt acggggttta
    23041 ctgatggccc ttccattcat cgccttcgcc tcgctgacca tgctgctgac ctccggggcc
    23101 gagaccgccc tggccatggg attgcgggtc agcacctcgg tcctccttct cctccttctg
    23161 gtctacacta ccccgttcat ggaccttctt tggacgatgc gctggttcaa gatgccctcc
    23221 ctgctcagcg acatgatcat gttcacctat cgcttcatat tcgtgatgct agatgaggcg
    23281 gaaaggatgc gtatggccag gaggtctcgg ggatttcagg gcggccgctc gctgctggac
    23341 cgcgaggcgt tcaaggtgct ctcgaacacc atcggcatga tcttcatccg ttcctatcgt
    23401 cgggcggacc gggtgtatat ggcattgctt tcccgcgggt acgatgggaa ggtacgcacg
    23461 ttaagcgcgt tccgggtccg cctcagggat gccggcctgg gcctggcctt cgtcatcatc
    23521 ggtggctttt cgttatctca gcagatgggg tggtacgtat ggtggtgatc tcccttcgtg
    23581 atgtttcctt cgaatacccc ggacatatcc aggccttgga gaacatcagc atcgagctaa
    23641 aggaagggga gcgcatagca ctgatcggcc cgaacggagc tgggaagagc acgctcctgc
    23701 atttaatggc cgccttggac ttcgccaagc agggagacgt atacatagca ggaaagaagg
    23761 tcgagaggcg cgcggcggcc gaggcccgca agaaggtcgg attcctattc caggacccgg
    23821 acgaccaggt gttcatgcct tcggtatacg aggacgtggc cttcggaccg ctgaacatgg
    23881 gactggcaga agaggaggta cgagaaaggg tcgataaggc gctggaggcc gtaggcgcaa
    23941 cgcacctttc caagcgtgtg cctcagaacc tctcgttggg agagaagaag cgggtggcca
    24001 tggccggcct gctctccatg tccccgccgg tgctgctgtt ggacgagccg acggccaacc
    24061 tggacccgca gggacgacga gacctggtca acgtcctttc cggactggag cagagcatgg
    24121 tcatcgccac tcacgatctg acggtggctt tcgagctggc cgatcgtgcc atcgttctga
    24181 agaggaaggt gctcttcgac ggtacgttcc gggacctcat gaagagaccg gacgtgctga
    24241 aggaggccaa tctggagctg ccatcgttct cccgtctgat ggtgatgtac aaacagcata
    24301 ccaatggcga cttcgagccg ccgctgacgg tcgaggaggc tttcgaagtg ctcaaggcca
    24361 acctacgttg agaacggatg gacccgtccg ggatgggtgg gggatagcaa cgaactcacc
    24421 gttgaagggt cattgttatt atgcaccgaa cgttccatat ccctttttag acgaaccggg
    24481 accgggaggt ggatccgatc agacgcgggt tagggaaggc acatcttctg tggaatcgtt
    24541 ggaccatctt cggcgtcatg gccctcacct atttcctagt gtactttcac cgggtatcgc
    24601 cggcggtact cgccaccgac ctgcagggat cgttcggggt cggtctgacc gccgtcgccc
    24661 tgctcagctc cgcttacttc tacgcctaca tggtgatgca attgccctgc ggggtgctca
    24721 ccgaccgctg gggaccgcgc cgtaccgtct gcgccttcac cgccctttcc gccctgggag
    24781 ccttggtgac cgctctggcc agcagttttg agatggtggt agccggccgg gtgatgatcg
    24841 gacttggcgt ggccatggtg tacgttccga ccttgaaggt gctctcctcc tggttccgaa
    24901 aggacgagtt cagcaccatg accggggttc tgttgatgat cggcaacgcc ggaggtttgg
    24961 cggcggccgg gcctttggcg gcgatgtccg atcaggtcgg atggcggcag gtgttcctgg
    25021 tcctggcggt tctgaccgcc gtgcttacct ggtcgatgtg gctcctggtc cgggaccggc
    25081 cgcaggacgt gggactaccg gccgttgagc ggaccgagga ggaagatagg atcccgatgg
    25141 gaagcgcctt gcgccaggtg ttcagctcag ggatcaggtt ctggcccttc gctatcatct
    25201 tcttcttcat gtacggcagt ctgatggtct accagggtct gatgggcgga ccgtacttcc
    25261 gagatgttct gggctgggac aaggcggagt acggcttctc ccttaccttc gtaggcctgg
    25321 gaatgatcgc cggctgcccc gtctctggct atctatcgga ccgcgttttg cggtcccgtc
    25381 gtaaagtggt ggtcgccggc accctggcct tcgctatgat gtggggcatc ctctggttga
    25441 tgtccggccg ggtgaacgat cagatggcat acaccatcgt tcatttcctc ttcgggttct
    25501 tcgccggctg gtacgtgccg atatatgggc aggtgaagga cgccttcccc cgatcgatgt
    25561 ccgggacctc cttggccgcc ctgaacatat tccctttcgc cggaggggcg gtattacaga
    25621 tgatcgccgg cttcatgatg agcgagagct cattgaccga ataccgcgcg gtctggcttc
    25681 tcatgctctt cggaatgatc gtcgccgcga ttgccgccct catttccaag gagcgtccgt
    25741 cttaaggacc cttagaccaa cagagacgac tgtcaaacgt ccagatggcc catcagcttt
    25801 ctgagcaggg ccgatggctc cgccttctcc ggaacgacgt tcacctcgat cccgtaggcc
    25861 tccagcctct ccctggtctc ctgtcccatg gccgcgatgg tcagtccttc cagcagggac
    25921 agcgcctcat cctctccgct tcgttcctcc agctgcacca ggaacgcctg ggtatgggcc
    25981 ggggtcggga acaccagggc gtcgatgtcg ccgcggtcca ggcgttccat gatgtcctgc
    26041 atgtcctccc cttcgtccag cagcagggag tacaccggaa cgtcctccac cttccagccg
    26101 gtggccttca ggtcctccac caggcgcttg gagccctggt cggaacggag caaggccacg
    26161 gtcccccttc gggcctggga gccaaggtgc tggaccagcg cctcggtggt ggattccggg
    26221 gctatggacg acactttgag accgtgcctc tgcgcgctct gcgccgtgcg gtccccgatg
    26281 accaccagtt ccgcccttcc catggcctcc ttcgcccggt ccagcatttt tctacgcttg
    26341 gccatggtga ccagggcctc gatggccgtg ggacaggtgg ccacaagcac gtcgaaccga
    26401 ccagagaaca tgtcgatcag gaacagtgag aaattggaat cgtcgttggg ctccgcgcgc
    26461 aacggtgacg cgcatacaaa atcggccagc tggcggtgct cgcggcataa tggcatccag
    26521 cgttccgacg gccctatgat ggccacgacc ttcttcatgg agtaccgtac aacgaactgg
    26581 attatctatc ttctccgcca ggagattaca attaaatatt caggttccga tagaacaaac
    26641 atgcccatcg gagatcctat ggcttcgaac gatcccagag aggagaaggg aaggctgacc
    26701 agagtgtgga tggtcggtgt tcccgtcaat gacctggaca tcgccctgga tttttacatg
    26761 cagaaactgg gacttgaact gcgacgtagg gacggcaact gggcggaact tggcccgggc
    26821 gagccgatgg gtaaggtggc gctgtacgta ccgagggaag gggaacgcca gcctggcggc
    26881 atgagcggcg tggtgttctc ctgtgacagc atgtacgaca tgcatcggcg gctggtggac
    26941 gagggcgtgg tcttcaagtt gaagccggaa aagcaaccct ggggcgggct gatggccgtt
    27001 ctactggacc aggacggaaa cgagctgatg gtgctggagc accctgatcg ctataggaaa
    27061 tgaaactcga tatccttaac taccatgggt aacaatcgca tagaggagat gagccaatgc
    27121 tggagataga gaaccttacc gtggaggttg gcggacggga gatcctgcac aacctgtccc
    27181 tgagcgtcat gaccggctac accacagtcc tgttcggccc caacggatcg ggaaaatcta
    27241 ccttgctgat gaccatcatg ggtttttccg ggtacaaggt caagtccggt cgcatcctgc
    27301 ttaatgggga ggacatcacc cacatgccgg tgaacgagag ggccaagcgc ggcatcggta
    27361 tgatgatgca gcggccgccg aaccttactg gggtcaggct caaggacctg gtgcgggtca
    27421 ccagcaaagg caacgtcgat accgacaagg tcgccgagga actggacatg gcccgcttta
    27481 tggagaggga cgtcaacgtg ggcttctccg gcggggagat caagcgctcg gagatccttc
    27541 agctgacggc ccagaacccc tgcctggtcc ttctggacga gccggagagc ggagtggaca
    27601 tggtctccat agagaagctg ggagccaagg tccatgatct gctgaccggc ccgacccatt
    27661 gcgccggatg gcgcgagaag agcggcaagg cggccctgat cataacccac accggacaga
    27721 tactagatta cgtggaggcg gaccgcggct acgtcatgtg ccagggcacc gtcgcttgct
    27781 ccggaaaccc gcgtgagctt ctggccgaga tccgcaagat gggataccag gagtgcataa
    27841 gttgcaaggt caacaaggcc gtacagataa aagagaacgc catctccgag gtctgaacat
    27901 gaccagcaac gatgagaacc gggccaagga tgccctcaag aagcaggcga agttcggcga
    27961 ggacattgac ctggacagct atcatgatgg aaagagggac atcgccgaga tggagtccct
    28021 ggaggacctt cccaaggaca ccaaagagac catgcacgat tccggactca cgccctccgg
    28081 gaagggacgc tccggtaact tcctgctgat ggacaacagc gtggtgcact cggccataat
    28141 gggcgagggc gtggagctca tgccccttcg ccaagcgcta aaggtgcacg actggttgaa
    28201 ggactatgtc tggaaggcgg tgcagcctga cgcggacaag tacaccgccg agacgtatct
    28261 ggcgaaggcg gacggctatt tcattcgggc gttgcctggc gccaaggtca agatgccggt
    28321 gcagacctgc ctgctgttga agaaccgcaa caccaagcag tacgtccata acgttctgat
    28381 tgccgaggaa ggctcggagg tggaggtggt caccggctgc gccaccacca agggcgtgga
    28441 gaagggactg cacctgggca tctcggagtt ctatctgaag aagaactcca agctgacctt
    28501 caccatggtc cacaactggt cggagttcat cggggtgcgc ccgcgcacca acatcctgat
    28561 ggacgagggc gccacgttca tcaataatta cgtagccctc aaaccggtga agaccattca
    28621 gacctatccg acggcgcaca tgaacggggc gaacggcatc tgccgcttca actccgtggc
    28681 ggtggcccat ccgggcagcg tcatggacct tggctcccgg gccatattga acgccccggg
    28741 ctgcaaggcc gagctcatct cccgaaccat aaccactggc ggcaccgtga tcgccagggg
    28801 gcagttggtc ggcaacgccc cgggcatcaa ggcccacctg gaatgcaagg gactgatcct
    28861 caataacaag ggcgtgcaga tcgccatacc tgaactggaa gcccgagtcc cggacgtgga
    28921 gatgacccat gaggccgctg tcggaaagat cgcccaggac caggtggagt acctgatgtc
    28981 ccgtggcctc acggaggagg aggcggtcgg catgatcgtc cgcggcttcc ttgacgtagg
    29041 catcagggga attccggacc acctcaaggc ggagatcgag aagatcctgc aggagaccga
    29101 cgtccgcggt tcctaggacg aaatcttaca aaccatttac cttatttttc aaagaaccaa
    29161 agtattaatc tcccgtataa ccatccctgc gcggtaatgc ctattgttcg ctggtaacga
    29221 attgcaagtc gagaccgcgg tgcataccgc ccttaagacc atgcgaggag tggagcgcga
    29281 tcagatagcc aggtttctga tcgacccggt cgtgctcttc attctggcag cgacatccag
    29341 gcgttgcctt accgtttctg agatggcccc ggtggtgaac cttccggcgg ccacctgtta
    29401 caagctgatc taccagatgg acaagatggg tctggtcgcc tattgcggca acggtcgcaa
    29461 cggaggacgg ggaaaggcgg ccgcctacac ctcggtgctc aaggagatgc acctggagat
    29521 gaggaacacc atcatcgtgc tccgggtcac ctggaagaac ggaaccaacg aggagttccg
    29581 caaggacttg gtacccccgt ccgcggataa gtgccccttt gaggtcgtga gccttctgac
    29641 ggccgaagct gacagcgcct tctctgactg atgattagga agattgatta gacgccataa
    29701 ctttgacctt agacatgcgc gtggtcaagc gttccgggga attggaggat tttgatccgg
    29761 ccaaggccat caatgccatc ttgagggtcg ggacgtcgcc cgaggaggcc gaggcgatcc
    29821 tggagtcggt caaaccgtac ctgtacgacg gcatgaccac cgaggaactt tatcggcgaa
    29881 tacgctcgcg gctgcccgcg cctcaggccc agcagtactc gctcaagaaa gcgataatgc
    29941 tcctgggtcc ggaagggcac gccttcgaat cattgatggg aagggtgttc gagcagatgg
    30001 gataccaggt gctggtgcgc cagatcctca agggcaggtg cgtctcccac gaggtggacg
    30061 tggtcatcgt gaaagatggc aagaaggcca cggtcgaatg caagttccac aacgccctgg
    30121 gcaccaagtc ctcgatacag gaagcgctgt acacctgggg gaggttcctg gacctcaagg
    30181 acacaaacaa tgtggaaaaa ccatggctgg tgaccaacac caagttctcc agcgaggtcg
    30241 ttcgttacgc ttgctgcatg ggcatgcacc tcatcggatg gaagtacccc gaggacgggg
    30301 gactggagag gatgatcgac gaggcgcaca tctacccgat aaccgtcttg gacatacggc
    30361 gttccgagca gcggaccctg ctctaccatg atttcgtgat ctgcgatgac atcgtggaga
    30421 ggaagccaga gctcctaggc ctgttcccca gagagaccgg ggaacggata atcaagaaga
    30481 ccgaggagtt cctgaggaac gtgaggtaat gaggttcagc gtggtactgg gcacccggcc
    30541 cgagatcgtc aagatgtcac cgatcgtccg cgagctgcag cgacgcggtc tcgatttcga
    30601 tctggtgcac accggtcagc attactcgtt cgagatggac cgggtgttct tccgggacct
    30661 ggagctgccc gaaccgcgca taaacctgga ggtcggctcc gggacgcatg gcgcccagac
    30721 cggcaagatg ctggccggtc tagagaggtt ctttcaggag acccggccgg acgtcgtgct
    30781 ggtgcagggg gacaccaata cggtgctggc gggagcgttg gcggccgtta aactaggcat
    30841 caccgtcggt catgtggagg ccggtctccg ctccttcgat cgcaccatgc cggaggagat
    30901 caaccgggtg atggccgatc acgtttccga ccttctgttc gcccccacgg agatgtccgc
    30961 ccgaaatctg agggcggagg ggctgcctga gaagcgcatc cacatcacag gaaacaccat
    31021 cgtggacgcg gtccgggaga acttggagat cgccggtggg aagggcgacg tcctgggtac
    31081 cttaggattg cgcaagggtg tgtacatcct gaccacattg catcgccagg agaacgtgga
    31141 ctcccgggag agactggcga acgtcctcat cggtctggag aaggccggtc gggagacggg
    31201 actggatgtg atctggccca tgcatccccg ggccaggaag aacctggaaa cgttcggact
    31261 gaggcttcct gagaacgtcc ggcccataac gccattgggc ttcctggagt tcctgcagtt
    31321 agagggaggg gcggccctgg ccctgacgga ctcgggcggc gtgcaggagg agagctgcat
    31381 ccttggggtg ccctgcgtta cgctgagaga caacaccgaa cgcccggaaa cggtggatgt
    31441 gggagctaac gtggtggtgg ggaccgaccc atccagaatt atcgcagggg tccgttccat
    31501 gctgtcccgg aaaggaggat ggacctgccc tctgggtgag aacggcgccg gcggacggat
    31561 aatcaccatt tgccaggaac gaaggaatca gaggtaacct tttctatacc cccgtttatg
    31621 ggctggaccg aggctgaagg atgatcgagg cagttctgga agtggatata ccggacagct
    31681 gggtccacga tatatcggcc aactttaacg tgccggttcg cattctggac tgcatacact
    31741 tcggcgaaca tggtgcgcgc tccttcgtgg aactggagtg caacgaccct gagatgcaac
    31801 agatcgtgtc ccgggccata gagaagcacc cggatgtgtg caaatgggag ccggccatcg
    31861 ccgaggatgg ccggatgaga ggtatcgcct tactaaccaa gtgccgggcc tgcaaagcgg
    31921 tcatgcggtc cgactgctat ttgcgttcgg cgaaaacgat aggcaatggc aaggtggagt
    31981 ggcagatcat cgctagccgc gaggccgcct tgggcgctct catcgatgaa ctaaagaaga
    32041 acggatgcgc catcactctg cggtccaaga aaacgctgga cgacaccagc ttcgtgacca
    32101 agaggcagga ggtggtagtg cacgccgccc tgatgaacgg ttattatgat tatcctcggg
    32161 gcgtcagcct gcagcagctg gccaagagtt ttgatgtaac cacctccacc atgggcgaga
    32221 tactgcagcg tggagagcgg aacatcatcc gggagtactt ccggaccaag atgtgaggtg
    32281 ttcgatatgg atgattcaga caagatagag gtaacgacca tggacgagaa ggactaccgc
    32341 ctcaagaagt ccctggccaa gatcaagcac aagatcgtgg tcatgtccgg caagggcggc
    32401 gtaggcaaga gcaccgtgac cgtgaacctg gccaccgccc tggccatgcg cggctacgag
    32461 gtaggcatac ttgacgcgga catacacggc cccaacatcc ccaagatgct caatatcgag
    32521 catgaggacg taatctccga cgaggatggg ctgctgccgg tgctggtgcc gccgcacatg
    32581 aaggtcatgt ccatggcctt cctgttacaa gatccggaca ccccggtggt ctggcgcggt
    32641 ccgataaaga tgggggcgtt gcgtcagttc gtggccgagg tgaagtgggg cgacctggac
    32701 ttcttgatcg tggacctccc gccgggaact ggggatgagc cgttgaccat agctcagctc
    32761 ctggaggacg cggacggcgc gataatcgtc accacgcctc aggacgtggc cttgctcgac
    32821 tcgcgcaaga gcgtgacctt cgcccaggcg ttgaaaatgc ccataatcgg aatagtggag
    32881 aacatgagcg gcctgatctg cccgcactgc cacaacacca tcgacctgtt caagaccggt
    32941 ggcggggaga gggcggccga gcagatgggc gtgcctttcc tgggacgcat accgttggac
    33001 ccgaacgtcg tcctgggcgg ggacgatgga tccccgatcg tgctccaaga caagtcgaac
    33061 ccggcctcca aggccttcga cgagatgacc gagaaggtac tagccaaagt gaacgggggg
    33121 aagtagatgg tccggttact ggtcacagcg gaaggtccga cccttgacga cctggtggag
    33181 gaggacttcg gacacgctcg ttacctcatc atcgtcaacc cggagacctg ggagttcgag
    33241 gctcacgaga acatcaagaa gcagacggac atgggccatg gcattatgac cgcggagaac
    33301 gtggccaagc tcaagccgga tgccgtgctg acaggctacg ccggagagca cggcagggcc
    33361 aagatgcagg acctgggcat ccggatgata atggacgaag agggcaccgt tcgggacgct
    33421 gtcaacggct acatccgaag nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    33481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    33541 aggaatatcc ggcgccctcc cgcgggcgcc gcccccgaac ggtcagaggc aagggggaat
    33601 gagacgggaa ctccgcccat cactatgagc ggaagagggc tgtcgaacac ttatgaacct
    33661 agggagggac ggaaatgaac caccgcatcc ttctgccgac caatggctcg ttgccagctc
    33721 tggtggccac caaggaagcg gtccgcctgg ccaaggagaa aggagccatg ttggtcatcc
    33781 tgaaggtagt agagcaggac ccggccatgt acctggagca ggtcagcgag gacctcgggc
    33841 ttcgcggcgg caccggtgtt gacggggtca tcttcgccca ggccctggct gctgaggccg
    33901 gagtcgggtc agagatcatc gaacgcgaag gcgcggtgac cggggagatc atccgagccg
    33961 ccgaggaatg ccaggtgagc atgatcgtca tgggcagctc caaccctcgc ggccttgcag
    34021 gattgtacct aggcaacgtg gccgaggcgg tgaccaagcg ggccaaggtg tcggtgtaca
    34081 ttgtaaagcc gaccgaggag gacctcgaaa tggctcttaa gctggccaag acgcccttac
    34141 ctacgccgga ggagaatgcg ttacgctcga tcatccgctc ccgcaagttc aaggtcggac
    34201 tggggctgtt cggcatctac ggggtgctgt ataccacgtt caccgtgcta ggcaccttcg
    34261 gacgagatat catgggcacc aggttagctg ggctgaacgt agggctgatc atgggaatga
    34321 ccgtgatcct gctggcgatc gtcatggcgg tgtccttcaa ttattacgcc gtgaaggtcg
    34381 agaaggaggg gcagtaaatg gccgcggtac ttgacaacag cttcaaaccg ttagccttcg
    34441 ccctcttcat gctgatcacc atagccacca tggccatatc ggtgtacttc tcccgccggg
    34501 tgaggacagc cggccattac tacgtggctg gaggcggggt aaaatggttc gtgaacggaa
    34561 tcgccttcgc tggggattat ctgagcgcgg cctccttcct gggcgtggcc gggatgatcg
    34621 ccttcagcgg attcgacggc ttcatgtacg gcataggatt cctggccggt tggatagtgg
    34681 cgctcttcct catcgccgaa ccgttacggg tgatgggcaa gtacaccttc gctgacgccc
    34741 tggtccacaa gttcaagagc aagcgcgttc ggctcgccgc cgccatatcg acgttagtgg
    34801 tgagcgtgtt ctatctgatc ccgcagatgg taggcgcggg gacgatcgtg cagccgctga
    34861 tcggcctcga ctacgcgtgg ggcgtggtga tcgtcggcgg catcgtgatc ctgataaccg
    34921 ccaccgccgg aatggtatcc actacctggg tgcagttcat aaagggactg ctcctgctgg
    34981 tggccgcgct cggtctgacc atagccgtgc tggtgctttc cggtttcggg ccgctggagt
    35041 tcataaccca cttcctggag aacggagcgt ccaatccctc caccgggctc tattcccatt
    35101 cgggggacgt gttcctggcg ccggggatca agttcaccaa tcccctagac tatgcttcgc
    35161 tggctttagc gttaatatta ggaacggccg ccctgccgca catcctgata cggtactata
    35221 cggtgcccaa gccctccgac gctcgaaaat cgaccgtggt ggctataatc gctatcgggg
    35281 cgttctacat catgacgctg ttcctggggc taggtgcgaa ctatttcgca ggacagggcg
    35341 agttcctgat caatgacagc aacctgtcgg cgccaacgtt agcgaacttc gccgggggag
    35401 aggtgttctt cgccatcatc tcgtcgatag ccttcgccac catccttggt acggtgtccg
    35461 gtcttatcat ggccgccgcg ggcgccatcg ctcacgatct gtacacggag atcctgggca
    35521 agaagaccaa cgagaggtcg gcgctgcggg tgtccaagct caccgcggtg ggcgtgggcg
    35581 tcatagccat tctgctaggc atactggccg aaggcatgaa cgtggccttc ctggtgggac
    35641 tggccttcgc catagccgcc tcggcgaaca taccggccct gatatgcacg ctgttctgga
    35701 agggggcgac ggagaagggg atagtgaccg gaatattcac cggcctggtg ctgtccatcg
    35761 tgctgatagt catcagcccg accctgatgg ccgacccgtt cttcagcctg aacaacccgg
    35821 ggatagtgag cataccggcc ggcttcgcgg tgaccatcgg ggtgtcgctg ctggataaga
    35881 agaagcagga ggtctcggtc gcgactaact gatctccgac ttcggcaccc aaacccttta
    35941 acttcttttc tataaaaaat gaataagaga ttttcagagc ttcaggtcat cgctccattt
    36001 cttctcggcc ttgatgtcca gccagggcat ctccaggcgt ttcggggaga cccgggtgtt
    36061 cgggtctatg gggttcggac cgagctgtct gaccttctcg atgtaaccgt tcaccgcctt
    36121 gacgtaaccc tcgacctcct ccgaatcgat gtaatcgatg tggaagcggt ccgggtggaa
    36181 gcccatctgc cccagatagg tatgcagcag ggtcatcctc tttctggtgc gcaggttccc
    36241 gatctcgtag tggcacctac cgggatgccc ggccaggacc agaacgccgt ccgcaccctt
    36301 ggataatgct tttaagaccc actccgggtc cacccgagcc gagcacatgg tgcgcagcac
    36361 gcagaagtgg gggtccatgg ccatgcgctt caggccggcc acatcggccg ccgtatacga
    36421 gcaccagtgg caggagaaca ccacgacctt ggggaaaccc atcttgctgt ccttgaggaa
    36481 cgtctcgatc tgggacagca tctgcaagtt ggagaagcag gtctggtcca gagcggccgt
    36541 gggacacgcg gcgacgcagg ccccgcaacc ctcgcaggca ttgatgttca cgttggcctt
    36601 cttgtggtcc tgataatcct tgtccggagc caggtggatg gcgttgaagt tgcacaccga
    36661 ttcgcagatg ccgcatccgg tgcagcggaa cttgttgacc tgggcgacgt tggccttctc
    36721 ggtcatggat tggttctgca ggcggtcgtg ggacatcctg agcatgtcct ccgccttgct
    36781 ggtggccgcc tcgcggtcgt tgaaatggat ccaggcgcac tgctcacgga tgttgcacat
    36841 ctccagcatg caccctttgc ggtcagcttc ctcgagggcc tgctggaact ccttgagata
    36901 gagcttggga gagcaggcgg cgatgagcac ccgatcgatg ccgtgctcct tggcgtcctt
    36961 ggcgatctgt tccctggcag ccggggagca ggcgaagtcc accacggcgg tgtgcgccac
    37021 cttggtcaat ttcttggcgg cctcgtgcaa cctgccggtg tccagactgt tgtcgatgtt
    37081 gccgccgcag cgacagatgt agatgcccat tctctgtgaa cccttgctca tccgatgatc
    37141 ctccagacag aactacgaag ggagaaaagt cttgctcttt tgttaaatag gtttccccga
    37201 aaccttcgta atcgagaagg ttcgggtttt atggtttata ggtctacgca gcggcgttgg
    37261 aaataggagc ggggatgctc gcaggacggg cacttctccg gtgcctcggt cccctcgtgc
    37321 tcgtaaccgc actcccggca cacccacttg gtgctcttct gctccttgaa cacgttgccg
    37381 gactcgacca gggctaaaag cttctggtac ttggtctcat ggtgcttctc cgcccttccg
    37441 atggcccgca gccgaacggc gatatcggcg tatccttcct tctccgcgac atcggcgaac
    37501 tccgggtaca tgctctccgt ctcgtagttc tcgccggcga tggcggcctt gaggttatcg
    37561 gcggtgcagc cctgcacggc cgggaactcg gcctcgaagt gcatcgcctc aaagcccagg
    37621 ttctccttct tcttcagatt ctggatcatc ttccacaggg agctggcatg ggacctctcc
    37681 tgctcggcgg tctccaagaa aacggcagat atctgttcgt acccttcggt cttagcggtc
    37741 ttcgcgtacc aggtgtaacg gttgcgggcc tggctctcgc ccacgaaggc cttggctagg
    37801 ttctcgatgg tcttcttcat gctttcacta ggcatggaat tgcaggatta cggatattag
    37861 gattgtgtcc gttttagagg gtcgaaaaaa gtttggcagg gaaacgttca attggcagga
    37921 gagagatggc ctaaaactgg catttcgtgc caagagggaa gatgaccgac aaagttaact
    37981 tcgatgacct gagcgtggtg gagcaggcgc tttacatcat tgacaactat gcggacatct
    38041 tcctggacaa tttaggactg gggctcaatc gccggcgaat cctgaacatc atgtacgagg
    38101 cgcgcaagca gctgatgcgc gaatggaact tcccgaaact ggtgatggtg ctggcgttcc
    38161 tgcaagagac cttccatcag gacctggagg tggagatcgg gatcttcaac ttcctccggc
    38221 ccttgagcag agaggaggcg gagagcaccg cggccctgaa ggccgagcag cacttcgaga
    38281 tggagaattt ccgtctggcc ttggtctact atcagctcct ggagaacgag tccggggaag
    38341 gcccggcgtc cgaaaaggta caggaatgcc tggccctcat cgataagtga ggttctcaga
    38401 tctcgctcgc cctcataagt tccagaccct tcttcagatc ggtcatcggg cggcctagct
    38461 ccgattcggc gaggtccacc gccagacagg agcgcttcgg cctcacggcc aacagaggca
    38521 tgtcctccgt cctcaccggt cttattaacg agtcgtccag atcgaaggcc tccgccaccg
    38581 ccgtgcctat ctgatagcgg ctcaggcagt ccggcccgct ggtatggcat atccctttca
    38641 actttcccag gcccagctgg agtatgtcgt tggccgccga cggggcgtag gtcggagaga
    38701 cgaactggtc gtcgtatagg cgtatcccct gacccttgcg cagcgaatcg attatccagg
    38761 tgacgaagtt gctcttattc ccgatgcggt tccaaccgta caccaccgac acccggcaca
    38821 ccaggttccc ccgcccggcg tccagggtca cgcgttctcc ttccagcttg ctgcgggcgt
    38881 aaacgctcag gggatcggcg ggctcgaact cgtgatatcg cccgcccttg agaccgttga
    38941 acacgtagtc cgtggacacg tagaccagct tgatacctgc ggaacggcat tcggcggcca
    39001 cgttcaacgt cccttccatg ttcaccttgt aggcggcatc cggctgacgc tcgcactggt
    39061 cgacgttggt catggccgcg ggcagcaata ccagatcggg gctggccgcc gatatcccgc
    39121 gggagacgga atcagggtcg gtgacgtcca tgtgcatggc gctggggctc ccgtccttga
    39181 ccgtgttgta ggtcccgacc atggccagtc ccagttgcgt tccggcgctc atcatgtact
    39241 gtcccagaag tcccgaggcg ccgatgacca tgaccctgtg catgcccgtc atatcgcctt
    39301 ggcgaattta ttgatttact cccaaatgcg aagcgggggg cgctcgccat ttcgcaataa
    39361 ttataaacgg gccaggcgta cgatgccgaa agaggtcgac cgatgtcgga tgtttgcgac
    39421 ggcgaaccca ttgataagct gacccttaaa gggaacggca taatcctgct caacatggcc
    39481 atgatggcca tgatggtcat gttcgtggag ataatgctgg tgcccgccct gccgctgatc
    39541 gctcaggaat ttccacagga cgcttcttgg atagcctggg tcctggcggc ctatatgctc
    39601 gtcggagcgg tggccacccc tctcatcggc aggctggggg acatgtacgg gaggaagcgt
    39661 atcctcctgg tatccatgag cttctatatg ctgggactgg tgggttgcgc atttgcctgg
    39721 tccataccct cgctgatcgc cttccgggcg gtgcaggggc tgggaatggg catgttctct
    39781 ctggccttcg gcatcgtgcg ggacaccttt ccgaccaagg tcataccaat ggccctgggg
    39841 ttgataagcg ccatgttctc ggtgggcgtt tcgatagggc tactgggagg aggcctgatc
    39901 atacagacct tctcctggag ggagagctac ctaataatca cccccctctt cgtcatcatg
    39961 gttctgatcg cctggaggac cctccgggac gaccgtaagc attgcagcgc cggtttggac
    40021 ctggcagggt cggccttgct gggagtggcg gtcctattgc tgctcgtttc tttgacccaa
    40081 ggcgaaaaat ggggctttac cgacctgcgg accgtgggca tggtcgttgc gtccatagtc
    40141 cttttcgcct ctttcgccat ctgggagagg aggacctcca atcccatcat tcagatgagc
    40201 ctgctcctga accgggggat attgggcgcc aacctggtcg ccctcttcta cggagtggcc
    40261 atgttccttc tgacccagac catacctttc ttcctgcgct ccccgcagaa ccttggcggg
    40321 ttcgccctga ccgacacctt cgtgatcgga ctttacatgg tgcctatggc cctgacccag
    40381 ctggtcttcg cgcctgccgc cgggtcctgg tccaagaaat atggtgcgga caaggtactg
    40441 atcgccggga tggccgtgtt cgccatcggg ataggcctgt tgatcgcctg gcattccgag
    40501 gattggatga tatgggtggc catgggcgtg caaggcatag gtatggcgtt ggccatggtc
    40561 tccttcataa acgtcgtcgg aatggccgcc ccgaaagggg actttggagt ggcctcgggt
    40621 atgaactctc tcttccgcat cgtcggaggt tccatcggcc cggtgctggc atccgccgtc
    40681 atggccggat acgcggtgat ggtggttctt cccttccaca ctgtggaata cacttcagag
    40741 gaagggtacg tggtgagctg ggcggtgggg gcggccttcg ccgtggtcgg gctgatcatc
    40801 gccctactgg tacgaccggg acggggcata agctatcagg attgacggaa tcattatgac
    40861 cgtgatacat gatgcaccca ggttagcatg aagatcgtat tcgtcaacgg gagcccccgg
    40921 ccggaaggca acaccgggac catgatgaag gccctggcca agaaagccaa ggagcgcggg
    40981 gcggaggtcg cctacttcga gatagtggac aaggacgtcc aagactgcga cggatgctac
    41041 cgttgcgata ccgaggaacg ctgccacaag gacgatgaca tgaccgatgc ctattcgctc
    41101 atccaatcgt ctgacatgct ggtgatcggt tcacccatct acatgggcgt ggagacgggc
    41161 atcaccaagt gcttcgtcga taggctctat tatctgatgg cccagaagcg ccttgcccgg
    41221 ggcaagaagg cgatcgcgtt gttcacctgc ggcctggcgg acggtcacat ggtctacggc
    41281 ttcatgcacg gccgcttcga caagcttctg cgtcttgacc tgggattcga ggaggtcaag
    41341 acgttcatcg tttccggcac gaggaaccgg gtggacctgg atgataacta ctatgcgcag
    41401 gagacgctca aggagatgga gaagttcatc ttcccggagt gagatggacg aagaggtcgt
    41461 aggctgtcag cattgcggct cgcgccgcat cgtgcccaag gtactggtcg gcggtcccat
    41521 ggccggagtg gacaacaagg acggttccta catctgtttg gactgcggcc gcgagctggt
    41581 accgctcggt ttcgaggggg agacggagcg gcaggacttc gtggcccatg cgcagagcgc
    41641 cggaaaggac ttcttgcata tcccgatcgt cccggtggat acctgggccc tgttcaacat
    41701 accgtttttg gacataccgg tggtcaaggt ggccaaggtc gtggaggtgg agtggaggga
    41761 tggttggaac gtccggccgg ggggcgtacc gttcgccgac tattggaagg cggtcggttc
    41821 caagcgctac ggggcggatg acgtgctatt gatggacctg gcgggaatgc agcacgcccg
    41881 gccgaacttt gaggcgttga aggccctgat gaaacgcaag tacgcggtct ggctagagat
    41941 gggcgtccgg aacgtgcagg acctgttcga cgctttcacc ctgggcgctc agaacgtgct
    42001 cctggggagc ctgacctgcc cgtccaagtc gatgctggaa gaggtcatcg aactgtccga
    42061 tatgagcatc ccgttgctgt actatgacgg aaaggtgctg tggtccggaa aacagcttcc
    42121 ctcggacctc tcggcatcgc tcaggatgct ggccgacctg ggcttcgaca aggcggccgt
    42181 gctggacctg cgacggctgg gcggcaaaga cggttatgac gttgatctcc tggacctggc
    42241 gttgtcctcc gacctggaga tgctgttcgg tggcggagtg cgcgaacccg acctgcccga
    42301 gctgagggac aagggcgcgg tcggaggact gctggaacct tacacgcctg tgcttcggag
    42361 tctaatagcc tcgcaaggcg tgcctgcgga tgacgagccg ttgccgacac cggtcagtag
    42421 agagagccct cgcggcttcg gcatcgacgg atgagaagat agacaacagt ttgatatggc
    42481 cataaccgcc ttggtgggaa ggtaatagaa tggagatctg ggagctggca gtggtcatcc
    42541 tggcggcggt ggtaccgtcg ctcatctacc tggtgtggat acgcaactcg gagaagtaca
    42601 accgggagcg gtggatgcac gtactctcgg tcttcctctt cggggcgatc atctcgatca
    42661 tcgccgcggt tctactggag agcgtggcca tcagcctgtt ctacgcttcc ggttccatat
    42721 tctccggagg gttctggtcc tacgaacctt acgaccccac cctggagata gtcatcctgg
    42781 ccgtggtcat cgcgcctctg gtcgaggaat ggaccaaggg atggggggtg atgaccgtcc
    42841 gcaacaagat ccgggagccg gaggatggtt tcatctacgg cgcggcggcc ggtctgggct
    42901 tcgccgccat ggagaacatc ttctacaaca gttccgccct ggtcggcggg ttcgatgtct
    42961 tcctgaccac ggccctgata agggcggtgg cctccacgct gctgcacgcc tccgcctcgg
    43021 cggtgttggg ttacgggata gcccgcaagt acctgaacgg ggcgaagggg aggcgcaccg
    43081 gatatctccc ctattacctg gcggcggtcg ttctccacgg gctcttcaac ggtttcgcgg
    43141 tggccgggga ggtcgtagac cattatgcca taccgataat aggactggta tcatcgaccg
    43201 tactggcgat agggatgttc ctatggatgc gccgccggtt gcggatcatg gaccggagat
    43261 ggaactgacc agctcggttc ccagtgcccg cgcactggcc cgtacttccg gatgttccgc
    43321 cgaataagcg gcgccgtccg ccccggccac cttgagcact ggccctggag cgataccgat
    43381 accgatgagg aacgccctaa gttcggagac ggcgttgtcg aacctggcat tgggctgcgc
    43441 cccggtcaat atgatcgccc cgacaccagg cttccttccg tcctgcaaga ccttccgcct
    43501 ggcccataac gcctggcagc ggtccacgac gatcttggtt tgcgagctca tgccggagaa
    43561 gtagatggga gaagcgacga ttaccgcatc ggcctcctcc agggaatcgt acagagcgtc
    43621 catgtcgtcc ctgatcacgc atgaaccgtt gatgaaacag tcctcgcagg cctgacacgg
    43681 ggatatgttc agagaggcca ggtcgtagcg tatcacctca gcccccgaat ctcgcgccgc
    43741 atcgagcgcc tggtccagaa gcgtggcgga gttcccgttg cggcgcgggg acccgttcag
    43801 tccgatgacc agggtcattc ctcgcacgcc tctcggatgc ggaccttgag ttccttgaag
    43861 tatcccagac ctttgatgac gtagtcggac gccccggcgc gcatggcttg atagctgagg
    43921 tccggatcgt ccaccgcgct gacgaacatg atgatcgaat tgggctgcaa ccccctcacc
    43981 cgcggaagga ggtccatgcc gttggtgtcc ggcagaaggt aatcgagaag gaccacgtcg
    44041 tagggacgcg tcttggccat tgccaatgct tcggaaccag tacgggccac gaacagctcg
    44101 aactcctcct gagatagatg ctcccggcat aggtcggcgt gggccggatt gtcctccacc
    44161 atcagcacgg agagcctggc attctgactc aattgcacac cctcgacccg tttaatattc
    44221 ctggatattt atcattatcg tgccttgggc agcattatga caaatatcga acctttggtg
    44281 tgatcgccct tgatgcggtc ctccacccag accttgccct gatagcggtc caccagagct
    44341 ttgaccaccg ataggcccag accgtggctt tcggccgcca tcccggtgtc caggttctcg
    44401 aacctctgga acagttgcgg ttttcgctcc tcgggtattc ctttgccctg gtcccgcacc
    44461 tccaccctcc agtagccgac gtccccgatg tggtccgggc gcatcacgac ctccaccttc
    44521 ttcatgtcgc cgtacttcgc ggagttgtta atgacgttga agaacacgtc ccggaccagc
    44581 ggattggcca ttaccagggc ctcgccctcc gggtattgca gttccagcgg tatgtctgag
    44641 aacaggtagg aggtctttat ctcccgcact atgtcatgca gcagcgggac caggtccacc
    44701 gggacgagct ccaccgaggc gtccgactcc aggatgttcc acagcttgcg cacgtcggtg
    44761 atcaggttgg atatgttctg cgattgggcc agggcgctct tcacgtagcg gcgctgcctc
    44821 tcgtccaact tggggtcctt gatcagcatc tccaggaagc cgtgtatcgg gacgttgtaa
    44881 ttggcgacgt cgtgcgtcag cagtatgttg tatatcttct gggcggagac cttggacttg
    44941 atgtcctgga agcgcccgga gttcttgagg gccatggccg catgtagtga atagagctcc
    45001 atgagccggt actcgtcctg ggtgaaaggt tttcccggca ccttctccag ggtcatgacc
    45061 cctagcatct cgtccccgat cttgagcggg acgcagatca gcgaggacgg ttcctccggc
    45121 gtgccgtcca cctgcttggc cctctcgtcc aggtcggccc gctccaccag ttcccctttt
    45181 ccggttcggg cgacgtcgcc ggttatgccc tcccccacgt cgatggcgag cgcttccggg
    45241 tccacctcgt acttgctcag gtacgtcaaa gggatcagcc gggtgcctcc tcggtcgaac
    45301 ccgtaaatga tgcaattatc gctctccacc agctcccggg acttggagag gatgatgtcc
    45361 agcacctcac gataatccag ggttccggac accaggcgcg agatctcgaa cagcgtctgg
    45421 aactccgagc ccacgcgctg atagtgctgg ttgagcaggg agtagaagta gatcatggcc
    45481 atctgattgg agaagacctg caaggtgagc tttcgcgtct ccaggtcctc tatcggcgcc
    45541 ttctttccga acagcccggc gccgacgaaa tcgccgcgga agcgcagagg cagacagacc
    45601 aacgattgga accccagatc gctcgtggcc tgacagcagt ccgtgttgag cgcggagcag
    45661 gtgcagctct cgcccttggc catcttcacc gccaaggagc tgtcgcccac ctgggtctcg
    45721 aacagttccc gggcctgctt gaaatctatt ccggaacaga acagctgcgg ccggccgtcc
    45781 cagcccagca gccgcatgac cgcgaagtcc agaccttccc tccggagaag attgtccagc
    45841 tcgctctgga gcgtgtcctt gggatttcct tccgagatca ggtcggtgga cgattcggcc
    45901 aggaacatca aggcctcgtt gccgggaccc aatcgtccgc gcaggatggg cgggtcagcc
    45961 acggccagga ccaggtcctt gccgtcccgc aggaacggat gcagggacca ggtaagcttg
    46021 acggcgcgcc cttgaacctt catggtcaat gtcgcgaacg aagggagatc gggttgcacc
    46081 agtgccttgg cgaccttttt ggcctcctcc tcatcaccgt gcagcacgaa cgtcagttca
    46141 ttgccgtcca ggatgtcgcg gtcgacctcc aggaacctct ggaaggggga gttggtgctg
    46201 acgatatagc cgtcccgcga atagaccatg accattaggt cgtggtcttg caagatgtcc
    46261 aacaccaggt ccaaggtcag ttcgcgttta tcgtcgtccg tcaggaaacc gatcagactg
    46321 acgcccacta tctcctcgcg ctccttcacc ggagtcacgg ataccaggaa tcgggcctgc
    46381 cccagctcca tcgtcaaacg ttcgcggttg ctcctgccct gcaggcattg ctgcaaggcg
    46441 gcgtccatga gcggagcggt gccgttctgc aagagcgaga ccagggcggt gcccaggaga
    46501 cgcgattcgt cggtggccag gagcgcctcg accgtgcggt tgtagtactt caatcggccg
    46561 ttgaggtcca acgtgcagat catggtccgt ccgacgcgat cccccagcct tccgccctcc
    46621 tctaagctca tgctgaacca tgcacccctt tttccttccc ttggattatc aattgttcag
    46681 ttatgaatta ttgcctttga atgttgcatg gacggaaata tgatgtccct gttcgggttc
    46741 gctgttcgct gaagtccgat aagaatattt ttccaataat tgagtcgtcc agcgctgcaa
    46801 taatttgaac atcgtgaaaa tatccagaga tgttaatata taatattttg aaatgaatac
    46861 atatccatcg tgacaatgct catatgaatc aacatgatta tatagtaaat cttatttgca
    46921 tcgattagag agcgcccgag cgagggaccc cccactattc tcctcctaaa gaatagtaac
    46981 attccacctt gcatccctcg ccgggcctct ttttctgtca cctgttttat ctagcgatgc
    47041 aacgttcccc gttcatgaac tcccccatgc gcctgggagc catggccacg ctccgggacc
    47101 acgagatgat atccgccttg aaggtggact tcctggagct gctggtgctt cccggggacg
    47161 atattccggc gatccgttcg ttctgcgaaa gcttcgacgg ggagctgatc ctgcacgcgc
    47221 cggaggagtt ttcggacggc aggttgctgg acctcagttc cctcgatcca tcatggaggg
    47281 aggcgagcgt gcgtagagtg cgggaggtca ccaaggccgg ggagggcacg gcccgtccgg
    47341 tggtcataca tccaggagga ataaccgaga ggccgttgga cgacgtgtcg gggatcatga
    47401 ccagccttca ggcttcgctg gacgcgcttc ctgattacac ctggctggag aacatgccca
    47461 tgcactatca tcaccgcgga cggacgctgt gctcgaacct catgcgcacc ccgtccgaga
    47521 tgaaacaggt ggacgccctg gtggccggct tcacggtgga cgtgtcccac gcctatcttg
    47581 gagttgctaa gaacggcaat gacaacgtac gagctatgtt ccaggagctt ggtgaggcgg
    47641 tgcgtcacgt tcatctttcg gacgcccgga ggccggacgt ggagggggtc atgatcgggg
    47701 acggcgagat tgacatgtca ttctttccct acctgcgggg attaccggtg ctgttagagg
    47761 tttgggacgg acacctcgat ggcggtgccg gtttccgaga ggccttgaag cggatgcggg
    47821 gccaataggc cagttgaccg gcgtgatgcc agaataccga taactacaaa aactgcaacc
    47881 gagataatag gcgctaccag ggtgcttgta ttggacgatg gagatttcac caaggctcgc
    47941 tcgatgcttt ttccgaggca ggttctggcg ggtcacgaca tcataggcac ggtgcccgat
    48001 tcctgcaagg acttcggtct tagcggcacc gctctcatcg tcaccggcga caagaccatg
    48061 aaggtggccg gcaacgccgt ccgggacgga ctggtcgcca acggttacga ggtgcagatc
    48121 gtaaacgtgg gagaggctac caacgacaac ctggacatag tgatgaaggc cgcgcacgag
    48181 tgccaggccg acttcttact gggcgtgggc ggcggttcca agatcgacct ggccaagatg
    48241 gccgccacca acctgggcaa ggagttcctg tccattccca cttccgcctc ccatgacggc
    48301 attgcgtccg ggagagcgag catccggtcc gtttccggac ccatctcaca cgaggccaga
    48361 gttccgttgg cggtcatcgc cgacaccgga ataatcgcca aatcaccata ccgcttattg
    48421 gccgcggggt gcgctgacgt cataagcaac gccaccgccc tcatggactg ggagttcgcc
    48481 cgtaggctgc gctacgagga gttctcccgt tcggcgtacg cgctggccag ttatacggcg
    48541 cagacaataa tcgagaacgc ggaccttatc cggcccaacc tggaggagag cgtgtggatc
    48601 gccatccgcc cgataatcat ctccgggatt tccatgagcg tggccgggtc gtcacgacct
    48661 acgtcgggta gcgagcacat gttctcgcac gccctggacc tcatagcgcc tggcaaggcg
    48721 ctgcatgggg agcagtgcgg ggtcggctgc ataatgatga tgtaccttca cggaggcgat
    48781 tggatgcgca tccgggaggc attgacgaag ataggagccc ccacttcggc caaggagctg
    48841 ggggtcagca aggagcaggt gatcgaggct ctggtgaccg cgcatcagat ccgcaaggac
    48901 cgcttcacca tactgggcat ggggctcacc agggaagcgg ccgaacggat agccaccatc
    48961 acccgcgtca tctagtcgag gaggtttgtc taatgatcac tgtcatcggg gagagacagg
    49021 ccaaggtaga tggtcgcttc atctacctgg ggccgctgac ggagtgcaag gagtgcaagc
    49081 tcaagggcgt atgcttcaat ctggacgctg gtgcgcccta ccgcatcgtg gaggtccgtg
    49141 acgtcaagca cgaatgcaag gtgcacgagg acggcgtccg
//
LOCUS       DAOPZI010000005        46464 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_636_length_46464_cov_10.843069, whole genome shotgun sequence.
ACCESSION   DAOPZI010000005 DAOPZI010000000
VERSION     DAOPZI010000005.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 46464)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 46464)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46464
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_636_length_46464_cov_10.843069"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..237)
                     /locus_tag="PKM11_02145"
     CDS             complement(<1..237)
                     /locus_tag="PKM11_02145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HNX47347.1"
                     /translation="MRPRVIVNCAMSPDGKIAGAERRQLRISSPEDMDRVKRLRADCQ
                     AILVGAGTILADDPHLTVKGRPPEKQALRVVLDPR"
     gene            314..1093
                     /locus_tag="PKM11_02150"
     CDS             314..1093
                     /locus_tag="PKM11_02150"
                     /inference="COORDINATES: protein motif:HMM:NF021287.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAC2 family protein"
                     /protein_id="HNX47348.1"
                     /translation="MNDFDIIELKRSNLRGATVIEGFSSIGLVGSITANYLVNLLDLE
                     LVAVIDSPYLPSVSIVRDGVPYSPVRVYSGVIGEKGSDKIVVIVSEFEPPQEILKPLA
                     WTIMDWVEDKGCKMVISPEGLANKSGEGVEEPEEKEGGELKVYAVASTPRARQLLVKN
                     DIPIFENGVVVGLAGVLLNEGANRGFDVVSILSEAHSDYPDARAAAAATEAIDKLLLH
                     SQLDTQPLLEEAALIEEALKEIKKKTGESEELAKKRSIMYG"
     gene            complement(1080..2090)
                     /gene="rtcA"
                     /locus_tag="PKM11_02155"
     CDS             complement(1080..2090)
                     /gene="rtcA"
                     /locus_tag="PKM11_02155"
                     /inference="COORDINATES: protein motif:HMM:NF003246.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003963 - RNA-3'-phosphate cyclase
                     activity [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HNX47349.1"
                     /translation="MIELDGSHGEGGGQTVRTALSLSALTGQPFHITDIRAGRPDPGL
                     KPQHLAGVRLMQRLCSAKVEGDAAGSRELTFVPGQITGGRFEHDVGTAGSLTLLMQAV
                     LPALVLSPVEVELNLKGGTDVRWSPPADHYQLVLFPLLRRMGAELEMTVESRGFHPKG
                     GGEVRLRVKGGPLEALRLEERGVLVRVLARACVQNLPEAVADRMIAAAGREVPGLVSE
                     KSVTMGPCPGAGITLAAEHQGTVLGWSALGDKGVSAEKVGQEAAACLKRVIELGGTLD
                     SRTADQLITYMALAKGDSSFSVGKISGHLTGQMHLLSQFLPVRFVIGETPPHRIDVIN
                     RT"
     gene            complement(2090..4819)
                     /locus_tag="PKM11_02160"
     CDS             complement(2090..4819)
                     /locus_tag="PKM11_02160"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF012905.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HNX47350.1"
                     /translation="MSTDFHAMSGEETLSALGSDEQGLSSEEARDRLVRYGPNELSEG
                     RKISPLMIFLDQFKDYMVIILIIAALISAGIGVWKDSTEEYLDAGIIMVIVLVNAVLG
                     FVQNYRAERTMQALREMAAPKANVIRDGQERSVPSRELVPGDVMIISTGDRISADARL
                     LESANLKTNEASLTGESLPVSKSAQEVFPSDTLLSDRENMVFSGCTVDHGRGRAVVTS
                     TGMQTQLGNIARMVQSEDEDTPLQRKLDRLGKQLGVMVLGVCVFIFVVGYLRGVAAEE
                     MFLTSVSLAVAAIPEGLPAVVTISLALGLQRMAKRKAVMRKLPAVESLGSATVICTDK
                     TGTLTKGEMNIREIFMGETVNVSGEGFEPQGRFVVQGETIDMAKREDLAMLLVAGALC
                     NDSSLYQEDGKWKVRGDPTEGTLIVTARKAGIDEGEVANNSPRIYEIGFDSVKKRMTT
                     VHQLDDRRMAFMKGAAESVIPLCSKRRVREKDLDMDKAAADSLLAKNNEMASRALRVL
                     AIAVRDVTDVPLEEAALERDLTFLGLVGMIDAPRKEALEAVRKCRTAGIRVIMITGDH
                     ELTARAIALEMGIAEPGRDKVVSGRTLETASDEELAELLKDVNVFARVAPEHKVRIVD
                     ALQARGEIVAMTGDGVNDAPALKKADIGVAMGITGTDVSKEASQMVLMDDNFASIVNA
                     VEEGRGVYDNIRKFVSFLLSCNSGEVIAMFAASLIFMDPEYIPFLLPVHLLWMNLVTD
                     GLPALALGVEPIEPNIMARPPNDPREPPVNRRTALRVLSIGGAFAFSALLAFSLVDVL
                     DLSRNGNYVQHARTVAFCTMVFSQLFFAFSARSQTLTIRKLGLLTNRKMIAAVAVSAL
                     LQLAVVYLPGLSDAFRTTQLGWEDWALILPISLIALVLNEAGKVVAARRARGA"
     gene            5051..7015
                     /locus_tag="PKM11_02165"
     CDS             5051..7015
                     /locus_tag="PKM11_02165"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX47351.1"
                     /translation="MIATDGLMFEVGIIMLIAFIGAAVASKARQSVILGYILAGMLIG
                     PFISVELFGYTYNGLVHDTGFVELLSSMGLTLLMFFVGLGFSMTKLKKTKAPAIILAL
                     MDVGLGMFLGILIGYALGWPIIDTIFLAGVISMSSVAITGKALEELERVSSPETEYLL
                     GTVIVESFLSMVLLTIVGGLMFKSDADSMNMTRLVVGILAFYVFFIFLAILVVPRVTK
                     YFERIKSNELFVLFALGLVFLSAALAEVAGVPAIIGAFFIGMVFAETKLAERIEDRIT
                     PFRDALVAVFFITFGMLIDLSMLYSIIPILLIAVPVSLFYEVIMLSSISYLLGFTSKA
                     ATFIGTAMTGRSSEAIMYASVGSASPAMTKGSELNPFAGAFCFLMSMVAPPLMKNSGK
                     LTNALIKVLPKFLIYSGTLINRTMSKIILPSTIKLFERTRRLEVLVIIYFVDLVCIMV
                     LPFPYNILAFVVGGLIVIVVYATLESDMYSIVRTVNYDNLGVVTRDPGHISRFISGFV
                     SLSLVTILSLAALFALWWASSIIVLMVYLIIVMSMARSVYKVTRTPAFNISVKPVKRR
                     TPRKKEKPFQPSFAAPDSRPDPGWDLETVAIERPSPAPMRRTDPGWELGPPDFEKVDE
                     RESFEPAKKRKPKDSAPVASESDEDKWGRL"
     gene            complement(7198..7545)
                     /locus_tag="PKM11_02170"
     CDS             complement(7198..7545)
                     /locus_tag="PKM11_02170"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HNX47352.1"
                     /translation="MTLIKKNFEKPDAIQNPPYLKVETIKIGEMTVVKQTYQPGWKWS
                     KHMKPLAGTDTCQGRHFGLWVSGRMHVKTDDGQEMEFGPGDVSDIPPGHDGWVVGNEP
                     SVFYAFIGGNAPK"
     gene            complement(7662..7733)
                     /locus_tag="PKM11_02175"
     tRNA            complement(7662..7733)
                     /locus_tag="PKM11_02175"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7698..7700),aa:Gly,seq:ccc)
     gene            complement(7772..8047)
                     /locus_tag="PKM11_02180"
     CDS             complement(7772..8047)
                     /locus_tag="PKM11_02180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0147 family protein"
                     /protein_id="HNX47353.1"
                     /translation="MEYDAKTKLKQIIDVLDQLADDTSVPRNIRRGATESKAKLNQDG
                     EAMDVRVAGAIGKLDDLANDPNIPMHGRTVIYRVISELENLLKTLNK"
     gene            complement(8080..8400)
                     /locus_tag="PKM11_02185"
     CDS             complement(8080..8400)
                     /locus_tag="PKM11_02185"
                     /inference="COORDINATES: protein motif:HMM:NF013224.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HNX47354.1"
                     /translation="MQQNDNDPILSSYYGDEEVTAIITLKVETKDADAVCENVSLLKP
                     TVDVFLVTGDTDIVVKAKFRNYTQLKRFLVEELSAVNGVKDTKTLMVVATFKEKGETI
                     SAPE"
     gene            complement(8481..8648)
                     /locus_tag="PKM11_02190"
     CDS             complement(8481..8648)
                     /locus_tag="PKM11_02190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47355.1"
                     /translation="MEESLCNVEFLKDNNNFVARVQSELGGLREYQSSSLEEVLEQVI
                     IDLQEEFENAM"
     gene            complement(8798..9196)
                     /locus_tag="PKM11_02195"
     CDS             complement(8798..9196)
                     /locus_tag="PKM11_02195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47356.1"
                     /translation="MVKIKVAKKADLAALDGKPNVLGGPSFSYSALEMFMMAPDFAVL
                     VAGSSALVIYHEGKGGKSRVLLMVGSSPDLLKGAEDSSRRAGTVKITLEAAPDSLALP
                     DLEAAGYRKAGNVANYFGKDRPALFLEKNL"
     gene            complement(9201..9638)
                     /locus_tag="PKM11_02200"
     CDS             complement(9201..9638)
                     /locus_tag="PKM11_02200"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47357.1"
                     /translation="MRARRAELSDLPAIMALEDGSFGPRRWDESFIRELMSDEGVLTM
                     VAEDPAIVAYVMFSISRPYETVEVLSLAVSPEFRRKGIAKMLMANIESLAERDARTVS
                     LCVRPDNQEAVNLYLSLGYKVLALCSGYYEDGSDAYMMVKHLE"
     gene            9730..11028
                     /gene="asnS"
                     /locus_tag="PKM11_02205"
     CDS             9730..11028
                     /gene="asnS"
                     /locus_tag="PKM11_02205"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HNX47358.1"
                     /translation="MSPYTSISALLRSPVSDGQVSLRGWIYRTRSSGKIVFSVVRDST
                     GIIQVTIKKGNLPDEQFEAAASASIESSVEVTGSMHQDDRAPGGYEVRASALRVIAPA
                     LPYPITEYQSEELLLDNRHLWVRSREQTAIMKVKATLLAGARDWLAENEFTEVTPPIF
                     TQNACEGGVTLFKLKYFDREAYLSQSAQMYLESLIFSLEKVYSITPSFRAEKSRTPRH
                     LTEYWHMELEEAWVDNDGNMKIQEELVSAMVAKVLQERREELELLKRDIEPLKAVAPP
                     FKRLRYSDMIDLLQKKGFDIEFGADLGAAEERAITEEEIAPVFVTNFPKECKAFYMKE
                     DPDDPRTYKCADLLAPFGFGEVIGGSERETDLNKILQRLEAAGIPEDPYRWYLDLRRF
                     GSVPHSGFGLGVERIVKWVCNLEHIRDAIPYPRTVARVYP"
     gene            complement(11019..12074)
                     /locus_tag="PKM11_02210"
     CDS             complement(11019..12074)
                     /locus_tag="PKM11_02210"
                     /inference="COORDINATES: protein motif:HMM:NF013696.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HNX47359.1"
                     /translation="MTRELVRNLIELLNVRSDTNEGKKALFELVRSKLEEMDLTIVTG
                     GASDSPAMVASNGTGGLAFSAHLDTVPAGEDWTREDGEVEAGRVYGLGAADMKGGMAA
                     MMAAARVLKEEGVPFSMLITSDEEELMTGAEFLVKRPEVRRASGILVGEPTDLRVAWK
                     EKGISRLTLTAHGVAAHASMPWNGDNAIMRLASLLDKLDPLLKVPDGPTDDLTLVVST
                     IRGGTRNNIVPDRCDAQLNARFPYPLTAKEVRERIMHNLEGESYDIIMQYELPAFETS
                     PDTALIRELLDAGADGIFAVPYATEAAVYSTVNPLVAVCGPGSPNMAHTKDEYVERWQ
                     LERAFRLYCEMGRRLQG"
     gene            complement(12079..13188)
                     /gene="gcvT"
                     /locus_tag="PKM11_02215"
     CDS             complement(12079..13188)
                     /gene="gcvT"
                     /locus_tag="PKM11_02215"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: protein motif:HMM:NF001567.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HNX47360.1"
                     /translation="MKRTPLYQEHLAAGARMVEFAGWEMPIQYSGIIEEHFQVRKQCG
                     VFDVSHMGDLLIKGPRAAIQLDGLLTNPISKAPVGKAVYGHLLTTDGQIIDDVITYHI
                     AEGQYLMVPNASNVDRVREWVISNTKGLEIFDLSTRLACLAVQGPSAEAVLQEMCSTD
                     LTTMKRFQGRFALLSGRSSSFLADHFPPEGEGVGCYIGRTGYTGEDGFEVLVEDRDAA
                     WLWNRLLQTGKVRPIGLGARDTLRLEMGYLLSGTDFDGSQTSLQTGPPWVIKMDHPFI
                     GRDVLILQKEHKYQVLVALKLTGKGVPRHGYDIMQGGKAVGKVTSGNMSPCLKEGIAL
                     GYVPQKLSAIGTELAVQIRDQAVPAKIVELPFYRK"
     gene            complement(13233..14387)
                     /locus_tag="PKM11_02220"
     CDS             complement(13233..14387)
                     /locus_tag="PKM11_02220"
                     /inference="COORDINATES: protein motif:HMM:TIGR02928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HNX47361.1"
                     /translation="MRNPRLFKDQSKLSFDYVPDKLCHREEQLERLEMLFRPVLDGSM
                     SQTAFLIGSVGTGKTATSKRFCLDLIKAAQEKGRPMDFIIVNCRQRSTEVAVLRRIVM
                     HFDENFPDRGFSTEEMLRSIRKHLEKRKMHLVVVLDEADVLLVKGASDLIYQLTRFDE
                     EVVGGRPSMSVIMISQKNVLDMLDAASSSTFRRANAIRFDRYGVRDLADILKIRADLA
                     FYPGTVRQDSLDLMADIAGEFGDARFAIELLDKAGMLAEEEGLEHLAPEQVRGAKALT
                     YSVVTESKIEDLDKQRKMVLLAVARAIKDQAYVKTPEAEAIYRLVAEEYGEKPRGHTM
                     FWSYLQDLTNQGLVGTKVTNEETGGRTTYISLPDVPAKVVRQRLEETLGA"
     gene            complement(14393..>15348)
                     /locus_tag="PKM11_02225"
     CDS             complement(14393..>15348)
                     /locus_tag="PKM11_02225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47362.1"
                     /translation="PMKLGEIYRFAVQLAKENDPRTGEEMEDELRRTEERYRKMDEEE
                     RGRFDLDSLWNPYPDSRLVHGDPETEIEGVLWGIDISTGEMVLADRLREKGRLIDAVI
                     GHHPFGRARPAFGEALHLHEYIYTQLGVPINVAEDIMAPRIREVHNLSAPANYDQAVD
                     AARLLEMPLMCLHSVTDNLVDRYLNDLVEKESPQRVGEVVDLLMRQPEHRHAAGNNNP
                     PEVYVGDRKRKAGKVVVRMTGGTSGPKEVYEKLAQAGVGTVVFMHIPEAHLEEVRKHH
                     LNVIIAGHVASDSLGINLLADRLEERGVKVTPCSGFIRTRR"
     assembly_gap    15349..15448
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(15491..15796)
                     /gene="rpl12p"
                     /locus_tag="PKM11_02230"
     CDS             complement(15491..15796)
                     /gene="rpl12p"
                     /locus_tag="PKM11_02230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein P1"
                     /protein_id="HNX47363.1"
                     /translation="MEYIYSALVLHAAGKQVSEDAVAAILKSAGVEPDASRIKALTAS
                     LEGVNIDEAIASAMVAAAPAAAAPAHAGSAAPAKEEPKEEEAVTEEEAAAGLSALFG"
     gene            complement(15809..16804)
                     /locus_tag="PKM11_02235"
     CDS             complement(15809..16804)
                     /locus_tag="PKM11_02235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HNX47364.1"
                     /translation="MAHVAKWKRERVQALVDLMVNSHVVGIVDLHGIPAAQMISMRAV
                     LRGKADVNMTRNTLMDLAITEAAKQRPGLEQLKQLVDGQCAIVTTDENPFKLFRQMEA
                     TKTPAPAKTGDIAPEDIMVKAGDTPFKPGPIIGELQKAGIPAAIEAGKIIIKKDKVLV
                     PKGEPVPDEVAKVLVKLEILPMIVGMDLRAAFEDGVLYGKNVLDVPADYYTNMLGLAA
                     RNALGLSLSIAYITPQTVTPLLSKAYREAMALSVAGAFPTKESIGAILAKADAQMMTL
                     ASITGLEDDRIKNRMAAVSASAPVKEVKATEAKKEDEEEQVSEEEAAAGLSSLFD"
     gene            complement(16818..17456)
                     /locus_tag="PKM11_02240"
     CDS             complement(16818..17456)
                     /locus_tag="PKM11_02240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020447957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HNX47365.1"
                     /translation="MAEKATVTAVKKALEHSPKRNFVQTVDLSINLKDVDMSIPKNRI
                     QEDIILPHGRGKPVKVCVFGSGEMVVKARDVADRVVSVEELGTIADDKKQAKKMANEF
                     EYFIAEAPLMPTIGKRLGIVLGPRGKMPKPIPPGADPKPMIENLRRSISVRSRDRLTF
                     HTAVGTTDMTPEDIADNIELIFKRLGMKLEKGTMNIRSAFVKTTMGPSEKVI"
     gene            complement(17586..18065)
                     /locus_tag="PKM11_02245"
     CDS             complement(17586..18065)
                     /locus_tag="PKM11_02245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HNX47366.1"
                     /translation="MAETIEVLVDGGKATPGPPLGPALGPTGINVVQVVAAINEKTRG
                     FVGMKVPVKVIIDQKTKTFEIKVGTPPTSALLFKELGIEKGAGAPKTGKAGNITIEQA
                     KKIAHMKQDSLTGADMKAQVMEVIGTCVSCGITVEGKEPRDMQAEIKAGKWDAQLKA"
     gene            complement(18070..18933)
                     /locus_tag="PKM11_02250"
     CDS             complement(18070..18933)
                     /locus_tag="PKM11_02250"
                     /inference="COORDINATES: protein motif:HMM:TIGR00405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor Spt5"
                     /protein_id="HNX47367.1"
                     /translation="MNDQETNQIPQYGNGPLTLSGPSNAQRVTAGSSAVWKLILKPRQ
                     ANKMKVRIVLTITYGTEDEPEWDIVLSQSSGKLWESAKLTVPDVEFSMEGMGGKEITL
                     SAESPRGARLDDSVHIKMQVIAEGQECGNMEFFANTMQSILILKTSIGHERAVVDGVA
                     GKAKIGNDKGIFALLAPGKLDGYVFMEAMNTDLVRETCRGVRKAKGLVDGETNLTEIE
                     HFLTPKPLVSGISEGDVVELVAGPFKGEKARVQKIDESKEEITVELFEATVPIPVTVR
                     GDSVRVLEKER"
     gene            complement(18956..19183)
                     /locus_tag="PKM11_02255"
     CDS             complement(18956..19183)
                     /locus_tag="PKM11_02255"
                     /inference="COORDINATES: protein motif:HMM:TIGR00327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase SEC61 complex subunit gamma"
                     /protein_id="HNX47368.1"
                     /translation="MDIVDKSWEIQKGIEERVKLLGKGRYGRVLKMARKPTYDEYTKT
                     VMIVGLGLVIVGGLGFTVYLLVTRLPGLLGL"
     gene            complement(19237..20340)
                     /gene="ftsZ"
                     /locus_tag="PKM11_02260"
     CDS             complement(19237..20340)
                     /gene="ftsZ"
                     /locus_tag="PKM11_02260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HNX47369.1"
                     /translation="MKSFISDAMSRAGPANESSMPSYKAQTAEDEELEKILLSLKTNI
                     KIIGCGGGGSNTIDRLYQTNLRDADLYAVNTDAQHLLIVRAHKKILLGRRSTKGLGAG
                     ALPQVGEEAAREAEEDLRKVLMGADIVFVTAGLGGGTGTGSAPYIAQLAKEMGALTIA
                     IVTSPFKAEGSIRAENAEWGMERLRSVADTVIVIPNDKLLDLVPRYSINAAFKVADEV
                     LMRAIKGITELITRPGLVNLDFNDLKTIMKGGGVAMIGMGEGEGDDKVEQAIDEAINS
                     PLIDVDITGANGVLINVTGGEDMSVSEAEKVAEVIQSKVNPNARIIWGASVDPALEGK
                     IRVMVVVTGVKSKYILGPKENTQPKGMAVDFIR"
     gene            20641..20835
                     /locus_tag="PKM11_02265"
     CDS             20641..20835
                     /locus_tag="PKM11_02265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HNX47370.1"
                     /translation="MKNRLRVYRTMTNLTQGALAEKLGITRQTVIAIEKERYDPSLDL
                     AFKMAKFFRVSIEDIFQYEG"
     gene            complement(20854..21975)
                     /gene="ftsZ"
                     /locus_tag="PKM11_02270"
     CDS             complement(20854..21975)
                     /gene="ftsZ"
                     /locus_tag="PKM11_02270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HNX47371.1"
                     /translation="MKSLVEEALARDDAPAKMEMAPNFGYQQLDSTDAELIELLKKLK
                     TNIKIIGCGGGGSNTINRISDENISGLETYAANTDAQHLLATRAHHKILLGRRSTRGL
                     GAGALPQVGEQAAREAEDEIRKAVTDAHIVFVTAGMGGGTGTGSASVVANIAKEMGAL
                     TIAITTTPFKGEGRMRMENAEWGLQRLRSSADTVIVIPNDKLIELYPRLGLNQAFKMA
                     DEVLTKAIKGITELITKPGLVNLDFNDVRTIMKGAGVAMIGLGESDGHAEDRAKEAIE
                     RALSSPLLEVDISGANGVLVNVIGGPDMTISDAEFIAEEVQRRVSPNARIIWGAAVDP
                     TLEKTIRVMVVVAGVKSKQIIGATNEAEKLKKADLDFIR"
     gene            22103..22375
                     /locus_tag="PKM11_02275"
     CDS             22103..22375
                     /locus_tag="PKM11_02275"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: protein motif:HMM:NF012911.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HNX47372.1"
                     /translation="MVYRVSVTFKGKVQGVYFRQYTRRWAEILSLSGYVKNMPDGTVL
                     AVFEGQRQAIQEIIRRLKEEHPESEVTSVEIKVEEPQGLEGFEISP"
     gene            complement(22372..23208)
                     /locus_tag="PKM11_02280"
     CDS             complement(22372..23208)
                     /locus_tag="PKM11_02280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HNX47373.1"
                     /translation="MMFEFPVLDNHAHLQPGGRHVEAVKDFLKAGGTHLIVSHMPYRE
                     TPVRCVDDFSKAYDITLRMAELARSAGAVAFCTVGPYPVQLLELAEVMSLDEATEVMK
                     GGMDLAARLVRERKAVALGEIGRPHFPVSDDIMTASNDILSYGMRLAKECSCPVVIHA
                     ESATPESLENLALMADRAGLPREKVVKHYCGPLVLPKENHGVFPSVLATRDMVQEALS
                     KGDRFLLETDFMDDLSRPGAVLAITTVPKRMRQLVEKGCDAEVLWKVNKTNPEKVYGI
                     DI"
     gene            complement(23205..23753)
                     /locus_tag="PKM11_02285"
     CDS             complement(23205..23753)
                     /locus_tag="PKM11_02285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TATA-box-binding protein"
                     /protein_id="HNX47374.1"
                     /translation="MATIKIENVVASTTLGEELDLPFIALSIDGADYEPVRFPGLIYR
                     IKDPKTATLLFRSGKVVCTGAKSLPDVDIAITKVAKQLEKAGIKIKQRPEIVVQNIVA
                     SSDLGHEIDLNAIAITLGLEKVEYEPEQFPGLVYRLDSPKVVVLLFGSGKLVCTGAKH
                     VEDVGVAVDNITEELKAAGLLK"
     gene            23979..24290
                     /locus_tag="PKM11_02290"
     CDS             23979..24290
                     /locus_tag="PKM11_02290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HNX47375.1"
                     /translation="MSDSERITVRIQAEKLGALQALVDGGKFPTISDAIRAAIDSFIE
                     TNFTPEHIQRVTVELPKVKVIELESLIRDGDSVSIDDAIRNAVREYVRMRLDKAMGEI
                     R"
     gene            24318..25346
                     /gene="ftsZ"
                     /locus_tag="PKM11_02295"
     CDS             24318..25346
                     /gene="ftsZ"
                     /locus_tag="PKM11_02295"
                     /inference="COORDINATES: protein motif:HMM:TIGR00065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HNX47376.1"
                     /translation="MGSRFEGMDEPEVELHELNILVVGCGGGGCNSIHRLNLIGIAAA
                     TTIAINTDQKSLKATECPNRLLLGVEYTKGLGTGGRPDIGEECALNASPMLSKIFQDA
                     DLVFIVTGLGGGTGTGASPVVADIARRCGAMVISIATTPFSFEGARRRNIAMKGLKRL
                     REASNSLLVLDNDRLLDIVENLPVDHGLAIIDQLISELIKGTVDILTTASLINLDFAD
                     LKTIMEQGGISTILYGENADPEGVVRDAINSPLLDVDIKGGTGALIHISGGSNLTMRR
                     ANKIVSSITKMLDDEATVKFGVRVEEGMEGNIRMIAIVTGISEVVDGMPTGAPGDDLG
                     KVLGKYGP"
     gene            complement(25347..26048)
                     /locus_tag="PKM11_02300"
     CDS             complement(25347..26048)
                     /locus_tag="PKM11_02300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HNX47377.1"
                     /translation="MPQVKVVLVEPRTDGNVGAVARSMANFGFTELCMVNPCELTDEA
                     FKRAKHAGYILKEAQVVSSFEEAIADCFHVVGTSGIVTAGEKHYIRIPLTPREFSERL
                     EDVEDKVAVVFGPEDTGLRQDELARCDLLVSIPSHEDYPTLNLSHAATIVLYELYQKQ
                     VHVGSPKKASEHEKEKMLEFFDDLLDAINYPQFRRERTSIMFRRMMGRAMPSRWEFHT
                     IMGVFGDAAKIIKKK"
     gene            26132..26950
                     /gene="truA"
                     /locus_tag="PKM11_02305"
     CDS             26132..26950
                     /gene="truA"
                     /locus_tag="PKM11_02305"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: protein motif:HMM:TIGR00071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HNX47378.1"
                     /translation="MGRVAVKFAYDGTRFMGSQRQPGERTAESELLKALLKIGAITSA
                     EENRFRVASRTDRGVSALGNVFAVDTEFRHQELLAAINASCDDVHCYALAEAPKNFSP
                     RRAQGRWYRYHLPYRGQNVELMNEGAKEFEGEREFRLFCKPDGKVTLRTIGSVTIRHD
                     GELIVIDIRAREFLRNMVRRIVSALDQLGQGRVTLEDVRSALQGRGRSMGLADPEGLV
                     LMDIDLELDWQYPPTGRMAAAIAEEAHKARVHLRFEEALQEKARLASRPPGDDI"
     gene            27101..27625
                     /locus_tag="PKM11_02310"
     CDS             27101..27625
                     /locus_tag="PKM11_02310"
                     /inference="COORDINATES: protein motif:HMM:NF024635.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase family protein"
                     /protein_id="HNX47379.1"
                     /translation="MLIALTGTPGTGKSSVSLGLQAKGWCILEVNDLAKRHGLLKSKD
                     PTRDSYDLDLDELQEALEKESFSDGVLVGHLSHLLDVDQVIVLRCHPQVLAKRLETRK
                     WPLAKIRENALAESLDIILAEAVDSEVPVFEINTTEMSLPETEEAVLSILAGEKEKYA
                     IGNIDWSEEALKWS"
     gene            27616..28251
                     /locus_tag="PKM11_02315"
     CDS             27616..28251
                     /locus_tag="PKM11_02315"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HNX47380.1"
                     /translation="MVLDSHRGKVDFLMDPVAKAMIKVHPNHISFMALALAAVAGVML
                     YFSFDNWVLLPISAVVVLVSGFFDGLDGKVARLAGIADRRGDFLDHVLDRYADMLMIG
                     GVAVSAWCSPYLGMMALVGVLLTSYMGTQAQAVGAKRMYAGILGRADRIVLSFLIPLV
                     QMVMVLLGHPDLELFGIQFNAFEVMMLWFAVVGNLTALQRAVLTYDWLRKA"
     gene            complement(28238..29290)
                     /locus_tag="PKM11_02320"
     CDS             complement(28238..29290)
                     /locus_tag="PKM11_02320"
                     /inference="COORDINATES: protein motif:HMM:NF016030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase large subunit PriL"
                     /protein_id="HNX47381.1"
                     /translation="MEFRDLALYPFLREATQFVKERQLGLEDLIGHTITAEARRRGRS
                     RVLTALSELAVPNNPVTSEDEAVQEILSYPYARILVSCIGDEALVRRYALAEAKTFNE
                     RLKKKDLATIIALARELEVEASLEDGTLSMHFTDFLSYTSGLRGPEWKLVNQDMRRGF
                     VLLEKNKFVRVLEQALDERIEDELPLPVNDELLEAVRSDLEEVIVALEAYKEKYRDEG
                     FGTVSIIKFPPCMKKLVATAQAGQNMPHAGRFALASFLSFIGMPVDDIIKLFCSSPDF
                     DQSKTAYQVRHITGDGYGKKYTPPECATMRTNGVCFEPDELCNGRRVNHPLTYYRIRS
                     YDRNRDKKADKTTKPS"
     gene            complement(29320..>29774)
                     /locus_tag="PKM11_02325"
     CDS             complement(29320..>29774)
                     /locus_tag="PKM11_02325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47382.1"
                     /translation="PTVSHTEFLHFKDRIREEIDRPLLERLVPVGTVLRSVYTEMREG
                     KVTFGRQIGTYPLLVGIPHPVDLEKFYDVAVVGHGFRSISAVVYPLPVNECHITSLEA
                     LPGLGRKRATRLFLARPMKGLDDLRKALDDPQVADAVLPFLSFDRPEH"
     assembly_gap    29775..29874
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<29875..30767)
                     /locus_tag="PKM11_02330"
     CDS             complement(<29875..30767)
                     /locus_tag="PKM11_02330"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47383.1"
                     /translation="MPEVLIFDGYIDEPGSLGVPPYIHPLPRAVFGAVRDAGGTPSYI
                     TVDQWRNGKKLPPSDLLVVLSGMSVPGRYLRGMPASRRELFQLIEGYRGETVLGGPAA
                     LDPVLKERFHHSHYLDAAAAVHDLMNSGKASDRWRGSEEWDRWMLLGADCVLSHPDHP
                     QPLTAELETYRGCVRYVNGGCSFCVEPLKGRPVFREPEAIVAEAGALRERGVVNFRLG
                     SQTCIISYKAELDGTDCPRPNPEALESLLSGMSALSPNVLHVDNANPAVMARHPAETE
                     RILISLVKHCTPGNVLALGMET"
     gene            complement(30823..31089)
                     /locus_tag="PKM11_02335"
     CDS             complement(30823..31089)
                     /locus_tag="PKM11_02335"
                     /inference="COORDINATES: protein motif:HMM:TIGR00489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 1-beta"
                     /protein_id="HNX47384.1"
                     /translation="MGTVAATYALMPEDTEFDFPALIAKLATIIPANVKVANTEIKPL
                     AFGLKMLEAAFVMEDAPGLVDKLEEALRAVPGIQNVETMQVSLL"
     gene            complement(31100..31267)
                     /locus_tag="PKM11_02340"
     CDS             complement(31100..31267)
                     /locus_tag="PKM11_02340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc finger domain-containing protein"
                     /protein_id="HNX47385.1"
                     /translation="MENEKICNSCGVRLVGNGITFFKCPICGAEEIGRCAKCRDQSVK
                     YECKKCGFIGP"
     gene            31611..31744
                     /locus_tag="PKM11_02345"
     tRNA            join(31611..31631,31662..31744)
                     /locus_tag="PKM11_02345"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31675..31677,aa:Lys,seq:ttt)
     gene            31857..32132
                     /locus_tag="PKM11_02350"
     CDS             31857..32132
                     /locus_tag="PKM11_02350"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: protein motif:HMM:NF007129.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit H"
                     /protein_id="HNX47386.1"
                     /translation="MIRLDDSVPFNVLKHMMVPRHELLSDEETDKVLKRLKITRDQLP
                     KIKDTDAAIKTLKAAMNRDIPEKSVVRIIRDSQTSETAEIFRLVIRG"
     gene            32129..35737
                     /locus_tag="PKM11_02355"
     CDS             32129..35737
                     /locus_tag="PKM11_02355"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit B"
                     /protein_id="HNX47387.1"
                     /translation="MNLLRDLVELYFRESSIVNHHIASFNDFLSSQSNPNSRMQKIVD
                     NVRVSAEDPERGMITLDPEKTNGRIIQIRVGRRRDEKTGQVDQHLPPTLKIGEPMVRE
                     ANGHTHNITPMEARLRNLNYIAPMHMDVTIIEDGIEREEKNIHIGDLPIMVKSRKCNI
                     FKENMEKEYDLTDEQYNVELMKKSEDPMDAGGYFIMGGTERVLITLEDLAPNRVMVEL
                     SERYGTAMEVAKVFSQKEGHRALTLVEKKRDGMLMVTVPAASGQIPLVALMKALGMED
                     DQQIYEAIVSSPEMANIVYANLEEIQDAKLYGPNGIFTTDHALTYLEKKFATGQAKEY
                     RVKKVESIIDRSLLPHLGDVEEDRMKKAIFLGRIARSVLELSLGKRKEDDKDHYANKR
                     LKLSGDLMEDLFRVSFTNLVKDMKYQLERSYARRKDLVVKSSIRPDLMTHRLQHALAT
                     GNWVGGRAGVSQLLDRTSNMGTISHLRRVTSSLTRSQPHFEARDLHPTQWGRLCPNET
                     PEGQNCGLVKNAALIINVSEGFREEDVTFLLKDLGIHEVKGQQMAGTRVYVNGDLKGV
                     HDHALDLVNQMRNRRRTGLLSDEINIRYDAEMDEVIINCDEGRLRRALLVLKDGHLMI
                     TRKHLEDIRAGKLRWSDLVREGILEWIDAEEEEDTFVSVEPYEVPLRCGNCDRDISPL
                     DMDWMNPGTTDRQAELKCRHCGGTTKVDYLFDKAHTHMEVDPMVILGVCAGMVPYPEH
                     NSSPRVTMGAGMAKQSLGLASSNYRKRPDTRGHILHYPQKPMVQTKFMDFVAFNQRPA
                     GQNFVVAVLSYHGYNMEDALILNQSSVQRGLGRSTFMRTYRTEERRYPGGQEDHFEIP
                     SPDVRGARTDSAYNNLSEEDGLISPETPVSGGHVLVGKTSPPRFVEEEEANFLSGHKR
                     RETSVTVRSGETGWVDSVMLTESENGSRLVKVKVRDERIPELGDKFASRHGQKGVVGL
                     LVPASDMPFTTDGIIPDLVINPHAIPSRMTVAHVLEMIGGKVGSLEGRSVDGTAFSGE
                     REDALRQSLVDAGFEKSGREVMYDGLTGRMIQADVFIGVIYYQKLHHMVSGKMHVRSR
                     GPVQILTRQPTEGRSRQGGLRFGEMERDCLIGHGAAMVIKDRLLDESDGTFQWVCGNS
                     NCGHIAILDKRGSLRCPVCGNNTNVHMIQTSYAFKLLLDELLSLGVAMRLQLEDLR"
     gene            35734..38526
                     /locus_tag="PKM11_02360"
     CDS             35734..38526
                     /locus_tag="PKM11_02360"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit A'"
                     /protein_id="HNX47388.1"
                     /translation="MMSGVSKRIGSIRFACLSPDEIRKMSAIKIITADTYNDDGFPID
                     QGLMDTHLGVIEPGLMCKTCGHKVDECPGHFGNIDLAMPVIHVGYVKEIKKLLQATCK
                     SCGRLVLTEDDVKEYQARLDTMEELGSDAIDLREFAKETAKAAAVKATKEVCPHCGVE
                     QLKITLDKPTTFREEGHKLTPKEVRERLERIPDNDLIPLGIDPHACRPEWMVLTALPV
                     PPVTVRPSITLESGDRSEDDLTHKLVDVLRINQRLRENRDAGAPQLIVEDLWELLQYH
                     VTTYYDNQTSGIPPARHRSGRPLKTLVQRLKGKEGRFRSNLSGKRVNFSARTVVSPDP
                     WLSINQVGVPTFAARELTVPVMVTKDNLEILRNMVKRGPEPVGEVYAPGVNYIIRIDG
                     RRIRVTEKNAETVSEGLEIGYKVERHLMDGDVVLFNRQPSLHRMSMMAHVVKVMPGKT
                     FRLNLCVCPPYNADFDGDEMNLHVLQSEEARAEAHILMKVQEHILSPRFGGPIIGAIH
                     DHITGVFQLTYKNPHFDKAQTLFIVSKMGENTLPEPIIEGGKEMWTGKDLFSTILPKD
                     FNAQFKSHICMKCPKCEKEGCQYDAYVKIRDGKVLMGTIDDNAIGSGGGKILDKIARD
                     YGADRAREFLDDVTRLAIGAIMVKGFSTGIDDEDIPEEAKRQIDDKINNTFQEVDKLV
                     ASYRDGTLDQMPGRSLEETLEVEAMKKLGEARDEAGRIAGKHLGISNAAVQMAKSGAR
                     GSMLNLSQMAGCIGQQAVRGERLSRGYWNRTLPHFQQGDLGAQAKGFVKNSYKSGLTP
                     TEFFFHSMGGREGLVDTAVRTSRSGYMQRRLINALEDLKLKQDGTVRNTADSIIQFHY
                     GEDGVDPTRSVQGEAIDLDDVLRDVLGEHYADLLSRPDERKISLYATVEKDLMEAATD
                     EDDETEEADLDIGGDE"
     gene            38526..40079
                     /gene="rpoA2"
                     /locus_tag="PKM11_02365"
     CDS             38526..40079
                     /gene="rpoA2"
                     /locus_tag="PKM11_02365"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit A''"
                     /protein_id="HNX47389.1"
                     /translation="MAQKDFINALEKKGVPMDTIDIVKEKYTNQTDLVKASVSDLVEL
                     GLDKEAAEDLQTKLGKKEKPTRAPAKAKTGSRRKVEKNQPEAAAPVVYEIPDKSKKYS
                     PFEDQLFKKCEELKLRLPRRVILNIAHRLEGNDISKENLVKILKVANQKYSDHLMDPN
                     ESAGILAAQSIGEPGTQMTMRTFHYAGVAEINVTLGLPRLIEIVDARRIPSTPMMTLY
                     VNKELSSDVDTVKNIASNIEITTVLDLADIETDLHNLRLFIVPDQRKCLQKGLLDQDG
                     RPVRGQVAPIEMIRDKVSRLRGIVMVDDIDKESLPPKVELAGEAGIGYLCLVPKEPSF
                     KTLQKALDMVKVAKVKGVEGITRALLKKKDDQWVIFTEGSNLREVLKIDGLDHSQAYT
                     NSIQEVNEVLGVEAARNSIIAEASHTLDEQGLSVDIRHIMLVADLMTADGDVKAIGRH
                     GISGRKSSVLARAAFEITAAHLLTAAMTGEEDHLDGVAENIIVGQPVTLGTGAVNLVY
                     APVKKGASE"
     gene            40076..40357
                     /locus_tag="PKM11_02370"
     CDS             40076..40357
                     /locus_tag="PKM11_02370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30e"
                     /protein_id="HNX47390.1"
                     /translation="MIDLGRALKSAMTTGKVVFGVAQSEKTVRNGEAKLVIVAKNCPS
                     GYLVSKDHGVPVFQFEGTNMELGALCGKPFSVSSIAVIDKGASNILSLG"
     gene            40360..40788
                     /locus_tag="PKM11_02375"
     CDS             40360..40788
                     /locus_tag="PKM11_02375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusA-like transcription termination
                     signal-binding factor"
                     /protein_id="HNX47391.1"
                     /translation="MTADITFTEETLRYISLFEKITKARVRDCMETEEKLVYVVDPGQ
                     ANRAVGKAGENVIKLKNTTGKNIQVVEFSDDAETFIKNVFYNYGPEKVEIETRGTIVH
                     ATVTVDPAVKGRAIGKNGKNLKIARDLVNRHHNVQSISVA"
     gene            complement(40785..41846)
                     /locus_tag="PKM11_02380"
     CDS             complement(40785..41846)
                     /locus_tag="PKM11_02380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47392.1"
                     /translation="MRPIPMESSSCYTKRLSRGCRLCRKGSKMVLLVTGKCGESCYYC
                     PLSEAKKGKDVVYANELLVSKDEDLIREAEAIGAKGTGITGGDPLLVMERTQRYIRLL
                     KQRFGPGHHIHLYTSTIDREKFLRLQEAGLDELRMHPPIERWGSLEELGIAEAVQGLE
                     MKVGFEVPAVPGELKGLLSICRQAADIGLDFVNLNELEVSETNCQALLGRNFHVRSDV
                     SSAMQGSMETSWQVMEEAGDMVPVHFCSSSFKDQVQLRERLKRRAKRTARPRDLITSE
                     GMVLLGIIETDRPEEAVRSLEEQEVPSELFGWDEKRKRLEVALWVLEELAAALPYRCY
                     LVEEYPTADRLEVERQPLN"
     gene            41931..42581
                     /gene="pyrF"
                     /locus_tag="PKM11_02385"
     CDS             41931..42581
                     /gene="pyrF"
                     /locus_tag="PKM11_02385"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HNX47393.1"
                     /translation="MRKQSRVILALDEVRPEKAFQVAEQVHDLVDAIKINWPLVLATS
                     PETITRLSKMAPVICDFKVADIPNTVSLIVSQAVQRGAEGVIVHGFTGSDSVKAAVAA
                     ADGRKIFVVTEMSHPGGAEYTAPAAESLAKMAVDCGAAGIIAPATRPERVAVLRRIVG
                     DLLILSPGVGAQGGSASATLDKGADYVIVGRSIYGAEDPRSAALQVVKEAQGAHSR"
     gene            42701..>46464
                     /locus_tag="PKM11_02390"
     CDS             42701..>46464
                     /locus_tag="PKM11_02390"
                     /inference="COORDINATES: protein motif:HMM:NF014565.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004576 - oligosaccharyl transferase
                     activity [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="STT3 domain-containing protein"
                     /protein_id="HNX47394.1"
                     /translation="MATKQEGSSQPTDKQRSLSLSNFSRDLKDSWIGRNWQTVLLLAM
                     MVFLALFVRSYFGFSTSVDNGYLVSGGSDSYYHMRVIDHAVATGDHLVWDDMLNYPNG
                     MRNPRPPLYDWSVAVVGMLLSTVTGLAVKDAIGMSLVFSTAVWGALTVVPVYMLGRAA
                     FGRKAGMLGAFIFALMAGHIERTVLSNADHDAIVLFFVVFSFYFLLRSLQSVNGSRWV
                     SKWTDPKAILPGLKSYLRTNQLSLIYAALGGLCVAAVGLIWTGYTYLLIVVFVYFIVQ
                     LLVDRFRNADSMGVLIAVAAFFGIAFLVMAPAYVSLNLIVTWFDTPLSLFAIGMVGGL
                     MFVVTRDYPWTLVLPVFTAILLAALALLSVFNPALLDSIMSGQGYLVKSKLYDTISEA
                     QAPMFSNLAMSFGMVTFWLALIGVGYAVVKIPKNLNPSFIFVVVWVAISIYMASSAAR
                     FVFNASPAFAVSAGWMLGLIIDRLKFDGMIRGLRTDHGGLWKTIRTSVKIRHVLGAFF
                     IIVMILVPNVWYAVDAGIPSTTKNEYDAQVYHAMPDFLRPDNYDLKNGTNWYLGAFSY
                     GLTLPNQYWPVAWKWFAAQDTEKVAAMDRPAFVSWWDYGFEAIQEGGHPAVADNFQNG
                     YNFAGTFLMTQTEDGAIAMFIIRSVEYDVYWNTTQGQDTLDKMAEYGVDTVRFKDIMM
                     NPANYVDEVKNNPAVYGEIDDDLSPANARYIAARQVLTTLSKDQLVSLYNDVREITGN
                     DIGYVSVDSRLFPFTATSYNIFYAPAKLSDQRVDGNNIPYDYYTIYAVDIYGDQIPLD
                     QVTSSSYITSYEIVYTEAFYDTMLYRAFMGYGPSDIGETKQGLPGISGSLQGSPSMQG
                     WNMSNFRLVYRTAYYNPYSSEDVANHTDAWRAVSYDEAISMYNRIQAKELIGTVDLSS
                     SGLYSGVTFLQYYDGAIVKGQAVTDAGRPMAGIWVTVLDEYGIPHQVVKTDSDGRYSV
                     IVPFGEVTLVYSYGDLDPRMLYGTQLHSENLDITYDQAMRVEADVDKNDQLDYLIDLD
                     VVVSAGSLVGQVFLDNDGNGKYSAAADEALIGATVTFANATNGFRAQATSTADGYEIA
                     GISPMSGTISVDYQGHVFGTASVQVRMGSPVSKDLYVEPAGMNGTATLADGTAAGQIT
                     ISLLDRTNGQVFESITDSTGAYAFDGLLAGNYTIQTPDGTAIQSADVTLGVGDSLTKD
                     LVLYNSMRLSGLVSYNGNAISNAMVGLSGDLGNVWVQSDSRGRYSVVVPKG"
BASE COUNT         9069 a        14259 c        13558 g         9378 t
ORIGIN      
        1 ccgggggtcc aggaccaccc gcagggcctg cttctccggc ggccggcctt tcacggtcag
       61 atgtgggtcg tcggccagta tcgtcccggc acccaccagg atggcctggc aatccgcgcg
      121 taagcgcttc acccggtcca tgtcctccgg ggaggagatg cgcagctgcc ttcgctccgc
      181 cccggcgatc ttcccgtcgg gggacatggc gcagttcacg atcaccctgg gcctcatggg
      241 tggtgtatcc ccgaaggtca tcataaggat gatgggaagg ttgattaata gccttaaacc
      301 gatatccgcg ccgatgaacg atttcgacat aatcgagctg aagcggtcca accttcgggg
      361 cgccacggtc atcgagggat tttccagcat agggctggtc ggttccatca ccgccaacta
      421 cctggtcaac ctgctggacc tggaactggt ggccgtcatc gattctcctt atcttccttc
      481 ggtttccatc gtcagggacg gagttcccta ctccccggtc cgcgtgtact ccggggtcat
      541 cggggaaaag ggcagcgaca agatagtggt catcgtctcc gagttcgagc ctccgcagga
      601 gatactcaag cccctggcct ggaccatcat ggactgggtg gaggacaagg gctgcaagat
      661 ggtcatttcg cccgagggac tggccaacaa atctggcgaa ggtgtcgagg aaccggagga
      721 gaaggagggc ggggagctca aggtgtacgc ggtggcttcc accccccggg ccagacagct
      781 gctggtcaag aacgacatcc ccatcttcga gaacggggtg gtggtcggtc tggccggcgt
      841 tcttctcaac gaaggggcga accgcggctt cgatgtcgtt tcgatactat ccgaggccca
      901 ttccgattat cctgacgccc gggcggccgc ggcggccacc gaggccatcg acaaactgtt
      961 attgcactcc cagctggaca cccagcctct tctggaagag gcggccctca tcgaggaggc
     1021 cctgaaggag atcaagaaga agaccgggga gagcgaggag ctggccaaga agcgctccat
     1081 catgtacggt tgatgacgtc gattcggtga gggggggtct cacctatcac gaacctcacc
     1141 ggcaagaact gggacagcag gtgcatctgc cctgtcaggt gcccgcttat cttccccacg
     1201 ctgaagctcg aatcgccctt ggccaacgcc atgtaggtta tcagctggtc ggcggtgcgg
     1261 gagtccaggg tccctccgag ttcgatcacc ctttttaggc aagcggccgc ctcctggccg
     1321 accttttccg ctgatacgcc cttgtccccc agggcgctcc atcccaggac cgttccttga
     1381 tgttccgcgg ccagggttat cccggctccc gggcaaggcc ccatggtgac gctcttttcg
     1441 gacaccagtc ccgggacctc cctgccagcc gcggctatca tgcggtcggc caccgcttcc
     1501 ggcaggttct gcacgcaggc ccgggcgagc accctcacca gcactccacg ctcctccagc
     1561 ctaagcgctt ccaggggccc tcctttcacc ctcaggcgca cctctccccc gcctttgggg
     1621 tgaaagcccc tgctctccac ggtcatctcc agctccgcgc ccatgcgcct cagcaagggg
     1681 aacagaacca gctggtagtg gtccgccggg ggcgaccagc ggacgtcggt tccacccttt
     1741 aggttcagct cgacctccac cggcgagagg accagggcgg gaaggaccgc ctgcatcagg
     1801 agcgtcaggc tgcccgccgt ccccacatcg tgctcgaacc ttcctccggt gatctggccg
     1861 gggacgaagg tcagttctct cgatccagcc gcgtccccct ccaccttagc cgagcacagt
     1921 ctctgcatca gtcgaacgcc agccagatgc tggggcttga gaccggggtc cggcctgccc
     1981 gcccggatgt cggtgatatg gaacggctgg ccggtgaggg ccgacaaaga aagagcggtg
     2041 cgcaccgtct gccctccgcc ctctccgtgg gagccgtcca gctcgatcat caggcccccc
     2101 tggcccgacg ggcggccacg accttccctg cctcgttcag taccagcgct atcaggctta
     2161 tcggcaatat cagcgcccaa tcctcccagc ccagctgagt ggtacggaag gcgtcgctca
     2221 atcccggcag atagaccacg gccagctgga ggagcgcgga caccgccacg gcggcgatca
     2281 tcttacggtt ggtgaggagc ccgagctttc tgatggtcaa ggtctgcgag cgggcggaga
     2341 aggcgaagaa cagctgtgag aagaccatgg tgcagaaggc caccgtcctg gcgtgctgaa
     2401 cataattacc gttcctggat aggtccagta cgtccaccag cgagaaggcc agcagggcgg
     2461 agaacgcgaa cgctccgccg atggacagca ctcgcaacgc agtgcggcgg ttcaccggcg
     2521 gttcccgcgg atcgttcggc ggcctggcca tgatgttcgg ttcgatgggc tccaccccca
     2581 aggccagggc gggaagcccg tccgtgacca ggttcatcca cagcaggtgc actggcagca
     2641 ggaacgggat gtattccgga tccatgaata tcagactggc cgcgaacatg gcgatgacct
     2701 cgccggagtt gcaggacagc aggaaggaaa cgaacttgcg gatgttgtcg tagacccccc
     2761 ttccctcctc cacggcgttg actatggagg cgaagttatc gtccatcagc accatctggg
     2821 acgcctcctt ggacacgtcc gttccggtga tgcccatggc cacgccgata tccgccttct
     2881 tcagcgccgg ggcgtcgttg accccgtccc cggtcatggc cacgatctcc cctctcgctt
     2941 gcagggcgtc gacgatgcgc accttgtgct caggcgccac gcgggcgaac acgttcacgt
     3001 ccttcagcag ttcggccagt tcctcatcgg aggcggtctc caacgtgcgt ccgctgacca
     3061 ccttgtcccg tccaggctcg gcgatgccca tctccaaggc tatggcgcga gcggtcagct
     3121 cgtgatcgcc ggttatcatt atcacccgga tgccggcggt gcggcacttc cgaaccgcct
     3181 ccaatgcctc cttgcgaggg gcgtctatca tgcccaccag gcccaggaag gtgaggtccc
     3241 tctccaaggc cgcctcctcc aacggcacgt ccgtgacgtc cctgaccgct atggcgagca
     3301 cccgcagggc gcggctggcc atctcgttgt tcttggccaa cagcgaatcg gccgcggcct
     3361 tatccatgtc caggtccttc tcccggaccc ggcgcttgct gcacaggggg atgacgctct
     3421 ccgccgcccc cttcatgaag gccatcctcc tatcgtccaa ctggtgcacg gtggtcatgc
     3481 gcttcttgac cgaatcgaac cctatctcgt atatgcgggg gctgttattg gccacctctc
     3541 cctcgtcgat gccggccttg cgggcggtca cgatcagcgt tccctcggtc ggatcccccc
     3601 gcaccttcca cttgccatcc tcttgataca atgaggaatc gttgcacagc gccccggcca
     3661 ccagcagcat cgccaggtcc tcgcgcttgg ccatatcgat ggtctctccc tggaccacga
     3721 acctgccctg gggctcgaac ccttccccgg agacgttgac cgtttccccc atgaatatct
     3781 cgcggatgtt catctcgccc ttggtcagcg ttcccgtctt atcggtgcag atcacggtgg
     3841 cgctgcccag ggactccacg gccggcagct tccgcatcac cgccttgcgc ttggccatgc
     3901 gctgcagtcc cagggccagg gatatggtca ccaccgcggg aagcccctcg ggaatggccg
     3961 ccaccgccaa gctcaccgag gtgaggaaca tctcctccgc cgccactccc cgaagatagc
     4021 ccaccacgaa gatgaaaacg caaaccccca ggaccatcac gcccaactgc ttaccaaggc
     4081 ggtccagctt cctctgcagc ggggtgtcct cgtcctcgga ctgcaccatc cgggcgatgt
     4141 tgcccagctg ggtctgcatg ccggtggagg tgaccaccgc tctcccccgg ccgtggtcca
     4201 cggtgcagcc ggagaaaacc atgttctccc ggtccgagag aagcgtgtcg gacgggaaca
     4261 cctcctgggc gctcttgctc accggcaacg attctccggt gagggaggcc tcgttggtct
     4321 tcagattggc cgactccagg agccgggcgt ccgcggagat gcggtccccg gtcgagatga
     4381 tcatgacatc tccgggaacc agttcgcggg agggcacgct cctctcctgt ccgtccctga
     4441 tcacattggc cttgggggcc gccatctccc gcagggcctg catggtcctc tccgcccggt
     4501 agttctgcac gaaccccagg acggcgttca ccaggacgat gaccatgatg atccccgcgt
     4561 ccaggtactc ttcggtagaa tccttccaga ccccgatacc ggccgatatc agggcggcga
     4621 tgataaggat gatcaccatg tagtccttga actggtcgag gaagatcatc agcggggata
     4681 tcttccgccc ctcgctcagc tcgttaggcc cgtagcggac cagccggtct cgcgcctcct
     4741 cggagctaag tccctgctcg tcgctcccca gggcgctcaa ggtctcctcc ccgctcatgg
     4801 catggaaatc ggtcgacatt tatgactcga aaggcaacag gtttaaggtt tattataatc
     4861 gacgctggga gtttcagagg aaatgtagga aggccagatg tggacaatta taaataatct
     4921 ataatactat caccgggcgg gatgcactag ggtcaatgct caacaggctt ggccctcgat
     4981 aactggacgg gctaacgcca acgatacaga acctccagcg gacacagtga ctctcgcatg
     5041 gactggcgcg atgatagcaa ctgacggttt gatgttcgag gtggggatca ttatgctgat
     5101 cgccttcatt ggcgcagccg tggcctccaa ggccaggcag agcgtcattc tcggatacat
     5161 cttggccggg atgctcatcg gccccttcat ctccgtggag ctgttcggct acacgtacaa
     5221 cggattggtg cacgacactg ggttcgtcga gctgctgtcg agcatgggcc ttaccctcct
     5281 gatgttcttc gtcggtctgg gcttctcaat gaccaagctc aagaagacca aggccccggc
     5341 gataatcctg gccctgatgg acgtcggcct ggggatgttc ctgggcatcc tgataggcta
     5401 cgccctgggc tggccgataa tcgacactat cttcctggcc ggggtcatct ccatgagctc
     5461 ggtggccatc accggtaagg ccctggagga gctggagcgc gtctccagcc cggagaccga
     5521 atatctgctg ggcacggtca tcgtggagag cttcctgtcc atggtgctcc tgaccatcgt
     5581 cggcggcctg atgttcaagt ccgacgccga cagcatgaac atgacccgcc tggtggtggg
     5641 catcctggcc ttctacgtgt tcttcatctt cctggccata ttggtggtcc cccgggtgac
     5701 caagtacttc gagaggatca agagcaacga gctcttcgtg ctcttcgccc tcgggctggt
     5761 gttcctctct gccgccttgg ccgaggtggc cggggtcccg gcgatcatcg gcgccttctt
     5821 catcggcatg gtcttcgccg agaccaagct ggccgagagg atcgaggacc gcatcacccc
     5881 cttccgggac gccctggtgg cggtcttctt catcaccttc ggaatgctga tcgacctcag
     5941 catgctctac tccatcatcc ccatactgct gatagcggtc ccggtgtcct tgttctacga
     6001 ggtcatcatg ctcagctcca tctcctacct gctggggttc acctccaagg ccgccacctt
     6061 catcgggacg gccatgaccg gacgctcctc ggaggctatc atgtacgcca gcgtgggaag
     6121 cgcctccccg gccatgacca aggggtcgga gctgaacccc ttcgccgggg ccttctgttt
     6181 cctcatgagc atggtggctc ccccgctcat gaagaacagc gggaagctga ccaacgccct
     6241 gatcaaggtc ctccccaagt tcctcatcta cagcggcacc ctgatcaacc gtaccatgag
     6301 caagatcatt ctgccgtcca ccatcaaact gttcgagagg acccgacgcc tggaggttct
     6361 ggtcatcatc tacttcgtgg acctggtctg cataatggtg ctgccgttcc cctacaacat
     6421 cctggccttc gtggtcggcg gtctgatcgt catagtggtg tacgccaccc tggagagcga
     6481 catgtactcc atcgtgcgca ccgtgaacta cgacaatctg ggtgtggtca cccgggaccc
     6541 ggggcacatc agccggttca tatccggttt cgtgagcctg agcctggtga cgatactgtc
     6601 cctggccgcg ctgttcgccc tctggtgggc atcctcgatc atcgtcctga tggtctatct
     6661 gatcatcgtc atgagcatgg cgcgcagcgt ctacaaggtt acgcgcaccc ccgccttcaa
     6721 catcagcgtc aagccggtca agcgccgcac cccccgtaag aaggagaagc ccttccagcc
     6781 gagcttcgcc gcgccggatt cccgtcccga ccctggttgg gaccttgaaa cggtggcgat
     6841 cgaacgcccc tctccggctc caatgcgcag gacggacccg ggttgggaac taggtcctcc
     6901 ggacttcgag aaggtcgacg agcgcgagag cttcgaaccg gccaagaaac ggaagcccaa
     6961 ggacagcgcc cccgtcgcct cggagagcga tgaggacaaa tggggccggt tgtaagagaa
     7021 agatgggaac ggcacgtccc acggtgaatc tggctataaa aagaataatt atgtaaaaac
     7081 ggtggtaaga aaagctctcc ttttttcgat cggaaaaaca agaataatga aaaggggaga
     7141 ttctactctc ctcccccatc tcgtatgcgt tttcagaacg gctttatctc taacccacta
     7201 cttcggggca ttaccaccaa taaatgcata gaacaccgac ggttcattcc cgacaaccca
     7261 accatcgtgt cccggtggaa tgtcagatac atcgccaggg ccgaactcca tctcttgacc
     7321 atcatcggtt ttaacatgca tccgccctga gacccaaagt ccaaaatggc gtccttggca
     7381 ggtgtctgtt cctgcgagcg gcttcatgtg cttggaccat ttccagccag gctgatacgt
     7441 ttgctttaca acggtcattt ccccgatctt gatggtttcg accttcaaat atggggggtt
     7501 ctggatcgca tcaggttttt caaaattctt cttaataagg gtcattctct ccccataaaa
     7561 ttgtttggtt cacccggtat taataaattt atagacaccg ggtccaagca aaccatcccc
     7621 caatgataaa tcaaaattca atgtctgggt atgggagaaa gtgcggacac cgggattcga
     7681 acccgggttc gaagcttggg aagctccagt cctgaccact agactatgtc cgcttagggc
     7741 tagtagatta caagttcttg tttaaagttt ttcacttgtt gagcgttttc aacaagttct
     7801 ccagttcgga tatgacccgg tagatgaccg ttcttccatg catcgggatg ttagggtcgt
     7861 tggccagatc gtccagcttt ccgatggccc cggcgaccct gacgtccatg gcctctccgt
     7921 cctggttaag tttggcctta gattcggtgg ccccgcgcct gatgttgcgg gggacggagg
     7981 tgtcatccgc taactggtcc aagacatcga tgatctgttt gagctttgtt ttcgcatcat
     8041 attccatgca atcacttcct attgattcgg actggtccct cactccggag ccgatatggt
     8101 ctctcccttc tccttgaagg tcgccaccac catgagggtc ttggtgtcct tgaccccgtt
     8161 cacggccgac agctcctcta ccaggaacct tttgagctgg gtatagttac ggaacttcgc
     8221 cttgaccacg atgtcagtgt ccccggtcac caggaacacg tccacggtcg gcttgagcaa
     8281 ggaaacgttt tcgcacaccg cgtcagcgtc cttggtctcg accttgaggg ttatgatcgc
     8341 cgtgacctcc tcatcgccgt aatatgagga taatatcgga tcgttatcgt tctgttgcac
     8401 gcgcaaccct cctcgcacgc tcagagcagg ccgttcaggc ggctgtgctg gacattataa
     8461 agtgaaaaaa acggaagcga tcacatcgcg ttctcgaatt cctcttgcag atcaatgatg
     8521 acctgttcaa gaacctcttc caggctgctg ctctggtatt cccggaggcc cccgagttcg
     8581 ctttgcacac gcgcgacgaa gttgttgttg tctttgagga attcaacatt gcaaagagac
     8641 tcttccatga tcattcaccc cagtccaaca tccatgagcg ttggtctgtt tttgcgaatg
     8701 aacagttccc tatttaatag ttgtcttaag gcttagaatc actatccaga tgtctggcat
     8761 cagatattga ttataatatt attatataat aaattattta caaattcttc tccaagaaca
     8821 gcgccggtcg gtccttgccg aaatagttgg ccacgttccc cgccttgcgg tacccggccg
     8881 cttcaaggtc cggcagggcc aggctgtccg gggccgcctc cagggtgatc ttcaccgtgc
     8941 ccgctctccg ggaggaatcc tccgccccct tgagaaggtc tggggacgag cccaccatca
     9001 gcagcaccct gctcttcccg cccttcccct cgtggtagat caccagggcc gagctaccgg
     9061 ccaccagcac cgcgaagtcg ggtgccatca tgaacatctc cagggcggaa taggaaaagc
     9121 tcgggccgcc caaaacgttc ggcttgccat ccaatgcggc gaggtccgcc ttcttagcca
     9181 ccttgatctt gaccatctca tcactccaga tgcttgacca tcatgtaggc gtcgctgccg
     9241 tcctcgtaat agccggagca gagcgccagt accttatagc ccagggaaag gtaaaggttg
     9301 acggcctcct ggttgtcggg acggacgcag agcgacacgg tccgtgcgtc ccgctcagcc
     9361 agggattcaa tgttggccat gagcattttt gctatccctt ttcgtcggaa ctccggggat
     9421 accgccaagg acaggacctc cacggtctcg tacggtcggg aaatggagaa catgacgtag
     9481 gccacgatgg ccgggtcctc ggccaccatg gtcaggacgc cctcgtcgct catcagttcc
     9541 cgtatgaaac tctcgtccca acggcgtggt ccgaaggagc catcctccaa ggccattatc
     9601 gccggtaggt cggagagctc cgcccttcgc gctcgcacgt tccggaatcg gccaccaggc
     9661 tatatccgtt tgccggggga ccgaaataat ggaatacata gaagcagttc ttcaagggcc
     9721 agtggtcaaa tgtctcccta caccagcatc agcgcgctgc tcaggtcccc ggtttccgat
     9781 ggtcaagtgt ccctgagggg ctggatatac cggacgcgca gcagtgggaa gatcgtcttc
     9841 tccgtggtca gggactccac gggcataatc caggtcacca tcaagaaggg caaccttccc
     9901 gacgaacagt tcgaggcggc ggcgtccgcc tccattgaat cgtccgttga ggtcaccggc
     9961 agcatgcacc aggacgaccg cgccccgggc ggctacgagg tccgggccag cgccctccgg
    10021 gtgatcgccc ccgcccttcc gtatccgata accgagtatc agagcgagga gctgctgttg
    10081 gacaaccgcc acctttgggt ccgttcgcgg gagcagacgg cgatcatgaa ggtcaaggcc
    10141 acattgctgg ccggcgccag ggactggctg gccgagaacg agttcaccga ggtcaccccg
    10201 cccatcttca cccagaacgc ctgcgaggga ggcgtcaccc tgttcaagct caagtacttc
    10261 gatagggagg cgtacctcag ccagagcgcc cagatgtacc tggaatcgct aatattctcc
    10321 ctggagaagg tgtattcgat aaccccgtcg ttccgggccg agaagtcccg gacgccgagg
    10381 cacctcaccg agtactggca tatggagcta gaggaggcct gggtggacaa cgacgggaac
    10441 atgaagatcc aggaggagct ggtctccgcc atggtggcca aggtgctcca ggagcgccgg
    10501 gaggagctgg agctgctcaa gcgggacatc gagcctttga aggcggtcgc tccgccgttc
    10561 aagcgcctgc gctactcgga catgatcgat ctgctccaga agaagggctt cgacatcgag
    10621 ttcggggcgg acctgggggc ggcggaagag agggcgataa ccgaggagga gatcgccccg
    10681 gtgttcgtga ccaacttccc caaggagtgc aaggccttct acatgaagga ggacccggac
    10741 gacccgcgca cctacaaatg cgccgatcta ctggctccgt tcggcttcgg cgaggtaata
    10801 ggcggaagcg agagggagac cgacctgaac aagatactgc agaggctgga ggcggccggg
    10861 atccccgagg acccctaccg ctggtacctg gacctcaggc gtttcggctc cgtgccccat
    10921 tccggtttcg gtctgggcgt ggagcgcata gtcaagtggg tatgcaacct ggaacacatc
    10981 cgggatgcca ttccgtaccc ccgcaccgtg gccagggtct acccctgaag gcgccgcccc
    11041 atctcgcagt agaggcggaa ggccctttcc agctgccacc tctccacgta ctcgtcctta
    11101 gtgtgggcca tgttcgggct tcccgggccg cacaccgcca ccagggggtt caccgtcgaa
    11161 tagacggccg cctcggtggc gtagggcacg gcgaatattc catcggcccc ggcgtccagc
    11221 agttcccgga tcagcgcggt gtcaggcgac gtctcgaagg ccggaagctc gtactgcatg
    11281 atgatgtcgt acgactctcc ctccaggtta tgcatgatgc gttcccggac ctccttcgcg
    11341 gtgagcgggt aagggaaacg ggcgttcagc tgggcgtcgc aacggtccgg gacgatgttg
    11401 ttgcgcgttc cccctcttat ggtcgaaacg accagggtga ggtcgtccgt cggtccgtcc
    11461 gggaccttga gcagggggtc cagcttgtcc aatagggagg ccaagcgcat gatggcgttg
    11521 tccccgttcc agggcatgct ggcgtgcgcc gccaccccgt gcgcggtgag cgtcaatcgg
    11581 gatatgccct tctccttcca ggccacccga aggtccgtcg gctcgcccac cagtatccca
    11641 ctggcccggc ggacctccgg tctcttgacc aggaactccg ccccggtcat cagctcctcc
    11701 tcgtcggagg ttatgagcat gctgaacgga actccctctt ccttaaggac ccgggccgcg
    11761 gccatcatgg cggccatccc gcccttcatg tccgccgctc ccagaccgta gacgcgaccc
    11821 gcctccacct cgccgtcctc cctggtccag tcttcgccgg ccgggacggt gtccagatgg
    11881 gcggagaagg ccagtcctcc cgttccgttc gaagcgacca tggccgggct gtcggaagcc
    11941 ccgccggtca cgatggtcag gtccatctcc tccagcttgg agcgcaccag ctcgaacagg
    12001 gctttcttgc cctcgttggt atcgctgcgc acgttcagca gctctatcag gttgcggacc
    12061 agttctcggg tcatgtgatc attttctata gaacggcagt tcgactatct tggccggcac
    12121 ggcctgatcc cgtatctgga cggccagctc ggtaccgatc gccgacagct tctgcgggac
    12181 gtatcccaaa gctatccctt ccttcaggca gggggacatg ttgccgctgg tgacctttcc
    12241 caccgccttc cctccttgca ttatgtcgta accgtgccgg ggcacgccct ttccggtgag
    12301 cttcagcgcc accagcacct ggtacttgtg ctccttctgc agtatcagga catcccggcc
    12361 tatgaacggg tggtccatct tgatcaccca cggcggtccg gtctgcagcg acgtctggct
    12421 gccgtcgaag tccgtgcccg agagcaggta gcccatctcc aggcgcaggg tgtcccgggc
    12481 ccccagcccg atcggcctca ccttgcctgt ctgcaacaat cgattccaga gccaggccgc
    12541 gtcacgatcc tccaccagga cctcgaagcc gtcctctccc gtataaccgg tacggccgat
    12601 gtagcagccc accccctctc cctcgggagg gaaatggtcc gccaggaagg acgagcttct
    12661 cccggacagg agggcgaagc gcccctggaa acgtttcatt gtggtgaggt cggtcgagca
    12721 catctcctgc aggaccgcct ctgccgacgg tccttgcacc gccaggcagg ccaaccgggt
    12781 ggagaggtcg aatatctcca gccccttggt gttgctgatg acccactcac gcacccggtc
    12841 cacgttggag gcgttgggca ccatcaggta ctgtccctcc gcgatgtgat aggtgatgac
    12901 gtcatcgatg atctgaccgt cagtggtcaa caggtgaccg tataccgcct tgcccaccgg
    12961 ggccttgctg atcggattgg tcagcagccc atctagctgg atggccgctc ggggaccttt
    13021 gatcagcagg tcgcccatgt gcgacacgtc gaacaccccg cactgcttcc gcacctggaa
    13081 gtgctcctcg attatcccgg agtactggat gggcatctcc cacccggcga actccaccat
    13141 cctggccccg gcggccagat gctcctggta aagcggtgtt ctcttcatta tttcacccgt
    13201 tcaatggcgg aaacattatc aatagctttc cgtcaggccc ccagggtctc ctctagcctt
    13261 tgccggacca ccttggccgg gacgtccggg agggaaatgt aggttgtgcg tccgccggtc
    13321 tcctcgttgg tgaccttggt ccccaccagt ccctggttgg tgaggtcctg cagataggac
    13381 cagaacatgg tgtgccccct cggtttctcg ccgtactcct cggccaccag cctgtagatg
    13441 gcctcggcct ccggcgtttt cacgtaggcc tggtccttga tcgctcgcgc cacggccagg
    13501 agcaccatct tgcgctgctt gtccaggtcc tcgatcttgc tctccgtgac cacggaatag
    13561 gtgagcgcct tcgccccgcg cacctgctcc ggggctaggt gctccaggcc ctcctcttcg
    13621 gccagcattc ccgccttgtc caggagctcg atggcgaacc gggcgtcccc gaactccccg
    13681 gcgatgtcgg ccatgaggtc cagggaatcc tggcgcaccg ttccgggata gaatgccaga
    13741 tcggcgcgta tcttcagtat gtcggccagg tcccggacgc cgtagcggtc gaagcggatg
    13801 gcgttggccc ggcggaaggt agaggacgag gcggcgtcca gcatgtccag cacgttcttc
    13861 tgggagatca tgatgaccga cattgacgga cgtccgccga ccacctcctc gtcgaagcgg
    13921 gtgagctgat agatgaggtc gctggcgccc ttcaccagca gcacgtccgc ctcgtccagg
    13981 accacgacca ggtgcatctt ccgcttctcc aggtgcttgc gtatggagcg cagcatctcc
    14041 tccgtggaga agccgcggtc cggaaagttc tcgtcaaagt gcatgacgat ccttctgagc
    14101 accgccacct cggtggagcg ttgccggcag ttgacgatta tgaagtccat cggccggccc
    14161 ttctcctgag cggccttaat caggtccagg cagaagcgct tggaggtggc cgtcttacct
    14221 gttcccacgc tcccgatgag gaacgcggtc tgggacatgc tcccgtcgag caccgggcgg
    14281 aagagcatct ccaggcgttc cagttgctcc tcgcggtggc acagcttgtc gggaacgtaa
    14341 tcgaacgaga gcttggattg gtccttgaac aggcgtgggt ttcgcatctg aattaccttc
    14401 tggtccttat gaatccggaa cagggggtga ccttcacgcc cctttcctcc aatcgatcgg
    14461 cgagcaggtt tatgcccagg gaatcggagg ccacatgccc ggcgatgatg acgttcaggt
    14521 ggtgcttccg gacctcttcc agatgcgcct ccggaatatg catgaacacc accgtgccga
    14581 cgccagcctg ggccagcttc tcgtagacct ccttaggtcc cgaggtgcct ccggtcatcc
    14641 tcaccaccac cttgccggcc ttgcgcttcc tgtcccccac atacacctcg gggggattat
    14701 tgttaccggc ggcgtgccgg tgctccggct gtcgcatcaa cagatcgacc acctctccca
    14761 cccgttgagg ggattccttc tcaaccaggt cgttcaggta gcggtctact aggttatcgg
    14821 tcaccgaatg aaggcacatc aggggcatct ccaacagtct ggcggcgtcc acggcctgat
    14881 cgtagttggc cggggcgctc agattgtgca cctcgcggat gcggggggcc atgatgtcct
    14941 cggcgacgtt gatcggcacg ccaagctggg tgtaaatgta ctcgtgcagg tgcagcgcct
    15001 ctccgaaggc cggacgcgcc cggccgaacg gatgatgtcc gatgaccgcg tctatcaggc
    15061 ggcccttctc ccgcagtcgg tcggctagca ccatctctcc ggtggagatg tctattcccc
    15121 aaagtacgcc ctcgatctcc gtctccggat cgccgtgcac caggcgcgaa tcggggtagg
    15181 ggttccacag tgaatcgagg tcgaagcgtc ccctctcctc ctcgtccatc ttccggtagc
    15241 gctcctccgt ccggcggagt tcgtcctcca tctcctcccc ggtccggggg tcgttctcct
    15301 tggccaattg aacggcgaac cggtagatct ctccaagctt catcgggann nnnnnnnnnn
    15361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnga cctgagaagg ctcggtaaga ccggcccttt
    15481 tctggccttt ttagccgaac agagcggaga gaccggcggc ggcctcttcc tcggttacag
    15541 cttcctcttc cttaggctct tccttggccg gagcggccga accggcgtga gccggagcgg
    15601 ctgcggcggg tgcggcggca accatcgcgg aggcgatagc ctcatcgatg ttgacaccct
    15661 ccagggaagc ggtcaaggcc tttatcctgg atgcatccgg ctcgacaccg gcgctcttca
    15721 agatcgcggc aaccgcgtcc tcggacacct gctttccagc ggcgtgaagg accaaagcgc
    15781 tgtatatgta ttccatttcc ttacctcctc aatcgaatag cgagctcaga ccagcggcgg
    15841 cttcctcctc gctgacctgc tcctcttcat cttctttctt ggcctcagtg gccttgacct
    15901 ctttcaccgg agcggatgcg gagaccgcag ccatcctgtt ctttattcgg tcatcttcca
    15961 gaccggtgat cgaagccaag gtcatcatct gcgcgtcagc cttcgcaagg atggcaccga
    16021 tgctctcctt ggtcgggaac gcgccagcca cgctcaaggc catcgcttcg cgataggcct
    16081 tggatagcaa gggcgtgaca gtctgaggtg tgatataagc tatagacaag ctcaagccta
    16141 gggcatttct ggcggccaac cccaacatgt tggtgtagta gtccgccggt acgtccagga
    16201 cgttcttccc gtacagcacg ccgtcctcga aggcggcgcg gaggtccatt cccacgatca
    16261 tgggtaggat ctccagcttg accagcacct tggcgacctc atcggggacc ggctcgccct
    16321 tggggacgag gaccttgtcc ttcttgatga tgatctttcc cgcctcgatg gcggcgggga
    16381 tgccagcctt ctgcagctcg ccgatgatcg ggcctggctt gaacggggtg tcccccgcct
    16441 tcaccattat gtcctccggc gctatgtctc cggtctttgc cggggccggg gtcttggtgg
    16501 cctccatctg gcggaatagt ttgaacgggt tctcgtccgt ggtgacgatc gcgcactgtc
    16561 cgtcaactag ctgcttcagc tgctccaggc ccggcctctg cttggcggcc tcggtgatgg
    16621 ccaggtccat tagggtgttc ctggtcatgt tcacatcggc cttaccgcgc agcacggcgc
    16681 gcatggagat catctgggca gcgggaatgc cgtgcagatc gacgatgccg acgacgtggc
    16741 tgttgaccat gaggtcaacg agcgcttgca ccctctcccg tttccacttc gctacatgtg
    16801 ccatgcttgg atcctcctca aatcaccttc tcggagggtc ccatggtggt cttcacgaaa
    16861 gcggaccgga tgttcatggt gcccttttcg agcttcatcc ccaatctctt gaagatcagc
    16921 tcgatgttgt cggctatgtc ctctggcgtc atgtccgtgg tcccgacggc ggtgtggaat
    16981 gtcaatctgt ccctgcttct gaccgaaata gacctgcgta ggttttcgat catgggcttg
    17041 gggtccgctc ccggggggat cggcttgggc atcttaccgc ggggacccag tacgataccc
    17101 agtctcttac cgatggtggg catcaacgga gcttccgcga tgaaatactc gaactcgtta
    17161 gccatcttct tggcctgctt cttgtcgtcg gcgatggtgc caagctcttc cacggacacg
    17221 accctgtcgg ctacgtccct ggccttaact accatctctc cgcttccgaa aacacagacc
    17281 ttgacgggct ttccccttcc gtgcggcaga atgatgtcct cctgtatcct gttcttgggt
    17341 atggacatat ccacatcctt caggttgatg gacaggtcga ccgtttgtac aaaattgcgc
    17401 tttggagaat gctccaaggc tttcttaacg gccgtaacgg ttgctttttc tgccaattca
    17461 atccctcctg tagttccaac gagccaatga aggctctcct acagtttggt aagcccccct
    17521 aaacaccctg ccatttataa agatatcgta aaagtatggt taaaatgttt gaactgaaaa
    17581 gggtttcagg ctttgagctg ggcatcccat ttgccggcct tgatctccgc ctgcatgtcc
    17641 ctgggctcct tgccttccac ggttataccg caggagacgc aggtgccgat gacctccatg
    17701 acctgggcct tcatgtcggc gccggtcagg gagtcctgct tcatgtgggc gatcttcttg
    17761 gcctgctcga tggtgatgtt gccagccttc ccggtcttgg gggctccggc gcccttctcg
    17821 atccccagtt ccttgaacag cagggccgag gtgggcggag tgccgacctt gatctcgaag
    17881 gtcttggtct tctggtcgat tatgaccttg accgggacct tcatgccgac gaatcccctg
    17941 gtcttctcgt tgatcgcagc aacgacctga acgacgttga tgcctgtcgg gcccaaggcg
    18001 ggtcccagcg gcgggccggg agtggccttt ccgccatcca ctaacacttc gatagtctct
    18061 gccatttttt catctctcct tctcgaggac cctcacgctg tcgccgcgga cggtgacagg
    18121 gatgggcacg gtggcctcga aaagctcgac cgtgatctct tccttgctct cgtcgatctt
    18181 ctgcacgcgg gccttctcgc ccttgaaggg gccggcgacg agctccacta catccccttc
    18241 cgatataccg gacaccagcg gcttgggggt caggaagtgc tcgatctccg tgagattggt
    18301 ctccccgtcc acaagtcctt tggccttgcg cactccccgg caggtctccc tgaccaggtc
    18361 ggtgttcatg gcctccatga atacgtaacc atctaactta ccaggcgcga gcagggcgaa
    18421 gatgcccttg tcgttcccga tcttggcctt gccggccact ccgtccacca cggccctctc
    18481 gtgacctatg gaggtcttga ggatcagaat ggactgcatg gtgttggcga agaactccat
    18541 gttcccgcac tcctgtccct cggcgatcac ctgcatcttg atgtgcacgc tgtcgtccag
    18601 gcgggccccg cgcggggatt ccgcagaaag ggtgatctcc ttgccgccca tcccttccat
    18661 gctgaactca acgtcgggga cggtaagctt ggcgctctcc catagctttc cggaactctg
    18721 tgacaggacg atgtcccact ccggctcgtc ctcggtgccg taggtgatgg tcagaactat
    18781 cctgaccttc atcttgttgg cctggcgcgg tttgaggatg agcttccaga cggcgctgct
    18841 tccggcggtc accctctggg cgttgctcgg cccggatagg gtgagcgggc cgttcccgta
    18901 ctggggtatc tgattagttt cctgatcgtt catttgcagc cctcctggag tggcatcaaa
    18961 ggccgagcaa tcccggaagg cgggtgacca gaaggtagac ggtgaagcca agtccaccga
    19021 cgatgaccag gcccagaccg acgatcatca ccgtcttggt gtactcgtcg taggtaggct
    19081 tcctggccat cttcaggacg cggccatacc tgcccttgcc gagcaacttg acccgttcct
    19141 cgatcccttt ttggatctcc caggatttat cgactatgtc catttacacg cactcttgga
    19201 taacgcccta atccttcctt ataaataatc ctttctttac cggatgaagt ccacggccat
    19261 ccccttgggc tgggtgttct ccttcggtcc caatatgtac ttggacttga cgccagtgac
    19321 cacgaccatg acccggatct ttccttccag ggccgggtcc acggacgctc cccagatgat
    19381 cctggcgttg gggttgacct tgctctgtat gacctcggcc accttctccg cctcgctgac
    19441 gctcatgtcc tcgccgccgg tgacgttgat aagcacgccg ttggccccgg tgatgtccac
    19501 gtcgatgagc ggggagttga tcgcctcatc tatggcctgc tcgaccttgt cgtcgccctc
    19561 gccctcgccc ataccgatca tggccactcc gccgcccttc attatggtct taaggtcatt
    19621 gaagtccagg ttgaccaggc cggggcgggt gatcagctcg gtgatgccct tgatggcccg
    19681 catcagcacc tcgtcggcca ccttgaaggc ggcgttgatg gagtaacggg gcaccaggtc
    19741 cagcagctta tcgttaggga tgactatgac cgtgtccgcc acggaccgca gcctctccat
    19801 tccccactcg gcgttctccg cccgtatgga accctcggcc ttgaacgggg aggtgactat
    19861 ggcgatggtc agcgcaccca tctccttggc cagctgggct atgtaagggg cggaaccggt
    19921 gccggtccct cctcccaggc cagcggtcac gaagacgata tcggctccca tgagcacctt
    19981 gcgcaggtcc tcctccgctt ccctggccgc ttcctctccg acctgtggga gcgctccggc
    20041 acccagtccc ttagtgctcc tccgccccaa taggatcttc ttgtgcgctc ggactatgag
    20101 aaggtgctgg gcgtcggtgt tcaccgcgta caggtccgcg tccctcaagt tggtctggta
    20161 aagtcggtcg atggtgttcg aaccgccacc gccgcatccg atgatcttga tgttggtctt
    20221 caggctcagc aggatcttct ccagctcctc gtcctcggcc gtctgggcct tgtaagaagg
    20281 catgctagat tcgttcgccg gaccggctct tgacatggcg tcgctgatga atgatttcat
    20341 ggaggggcct cggacgggtg cggctagctc tcaagccctt agctgccact cgtctgagag
    20401 ctatcacgct atgcgaactt taaaacattt cggtgccaac agcctataac aataaaaaat
    20461 attgaatata tgttgcgatg aattgtaacg tccacacgtt gatgatttgt aatatttgat
    20521 tcctaaaaga atatttaatt tgtttgatgt atatattaat ttacaaaatg tattatttac
    20581 tttacaaaaa gtaaagttta atattcaaaa tgtaagttca accttacatc agtgagggca
    20641 atgaagaacc gtctcagggt ctaccgcacc atgaccaacc tgacgcaggg ggcgttggcc
    20701 gaaaaattag ggataacccg gcagacggtg atcgccatcg aaaaggagag gtacgacccc
    20761 tctctggacc tggcgttcaa gatggccaag ttcttccggg tatcgattga ggacatattc
    20821 cagtacgagg gctgagccct cgctggaaaa agatcaacga atgaagtcca gatcggcctt
    20881 cttcagcttc tccgcttcgt tggtggcccc gattatctgc ttggacttta ctccggccac
    20941 cacgaccatc acgcgtatgg tcttctccag ggtcgggtcg accgccgctc cccagatgat
    21001 cctggcgttg ggggaaactc tcctctggac ctcttcagct atgaactccg cgtcggagat
    21061 ggtcatgtcc ggtccgccga tgacgttcac cagaacgccg ttggcgccgc tgatgtccac
    21121 ttccagcaac ggagagctga gcgcgcgttc gatagcttcc ttcgctctat cctccgcgtg
    21181 accgtcgctc tctcccagac cgatcattgc cacgccggcg cccttcatga tcgtccgcac
    21241 gtcattgaag tccaggttga ccaggccggg cttggttatg agctcggtta taccctttat
    21301 cgccttggtc agaacctcat cggccatctt gaaggcctgg ttgagcccca ggcgcgggta
    21361 cagctcgatg agcttgtcgt tcgggatgac gatgaccgtg tcggcggaac tgcgcaggcg
    21421 ctgcagtccc cactcagcgt tctccatgcg catccgtccc tcgcccttga aaggggtggt
    21481 ggtgatggcg atggtgagcg cgcccatctc cttggcgatg ttggccacga cggaagcgga
    21541 accggtcccg gtgccgccgc ccattccagc ggtcacgaag acgatgtgcg cgtccgtgac
    21601 ggccttcctg atctcgtcct ccgcctcgcg agcggcctgc tcgcctactt gtggcaacgc
    21661 accggcgcca agtccccggg tgctccggcg tcccagcagg atcttgtgat gagccctcgt
    21721 agccagtaga tgctgggcgt cggtgttggc ggcgtaggtc tccagaccgg agatgttctc
    21781 gtccgagatc cggtttatgg tgttggagcc accgcccccg caaccaatta tcttgatgtt
    21841 ggtcttcagt ttcttcagga gctctatgag ctcggcgtcg gtggagtcca actgctgata
    21901 tccgaaatta ggcgccatct ccatcttcgc gggggcgtca tctctagcta aagcttcctc
    21961 aacaagtgat ttcatcgatc atcccatcct ttggccacgg ccatcttccg ataatgctcc
    22021 ccatatgata tttctattaa atattcttac tccccagagc cgacgagata atgatatact
    22081 aaggccgcac aatgttaatg atatggtcta ccgcgtctcc gttacgttca agggcaaggt
    22141 gcagggcgtt tatttccgcc agtacacccg ccgctgggcg gagatactgt ccctgagcgg
    22201 ctacgtcaag aacatgcctg acgggacggt cctggcggtg ttcgaagggc agagacaggc
    22261 catccaggag atcatccgcc ggctcaagga ggaacatccc gagtcggagg tgacctcggt
    22321 ggagatcaag gtggaggagc cgcaagggct cgaaggcttc gagatatcgc cctagatatc
    22381 gataccgtac accttctctg ggttggtctt gttgaccttc cagagcacct cggcgtcgca
    22441 tcctttctca acaagctggc gcatcctctt cgggacggtg gtaatggcca ggaccgcccc
    22501 cggccggctc aggtcgtcca tgaagtccgt ttccaacagg aagcggtcac ctttggacaa
    22561 ggcctcctgg accatgtccc tggtggccag taccgacggg aaaacgccat ggttctcctt
    22621 cggcaggacc agtgggccgc agtaatgctt gaccaccttc tccctgggaa gcccggccct
    22681 gtcggccatc agcgccaggt tctccaagct ctccggggtg gcgctctcgg cgtggatgac
    22741 caccggacac gagcattcct tggccaaccg cattccatat gacagaatat cgttcgaagc
    22801 ggtcatgata tcgtcggaca ccggaaagtg tggacgaccg atctcgccca gggccacggc
    22861 ctttcgctct ctgaccaggc gggcggccag gtccattccg cctttcatga cctccgtagc
    22921 ttcatccaag gacatgacct cggcaagttc gagcagttgc accggataag gtcccacggt
    22981 gcagaaggcc accgccccgg cggaacgggc cagctccgcc attctcagcg ttatgtcgta
    23041 cgccttgctg aaatcatcca cgcagcggac cggcgtctcg cgataaggca tatggctcac
    23101 gattagatgt gtgcctccgg ccttcaggaa gtccttgacg gcctcgacgt ggcgtccgcc
    23161 cggttgaaga tgggcgtgat tgtcgagcac cggaaattcg aacatcattt cagaaggccc
    23221 gccgccttca gctcctcagt gatattatcg accgccacgc cgacgtcctc gacgtgcttg
    23281 gcgccggtgc agaccagctt tccggagccg aagagaagga cgacgacctt aggcgaatcc
    23341 aggcgatata ccaggccggg gaactgctcc ggttcgtact ccaccttctc cagccccagg
    23401 gtgatggcta tggcattgag gtctatctca tgacccaggt ccgaagaggc cacgatgttc
    23461 tggaccacga tctccggtct ttgcttgatc ttgatccccg ccttctccag ctgtttggcc
    23521 accttggtta tggcgatgtc cacgtcaggc agggacttgg cgccggtgca gacgaccttt
    23581 ccgcttcgaa agagcagcgt cgcggtcttg gggtccttga tccggtagat caggccgggg
    23641 aaccgcaccg gctcgtaatc cgcgccatct atggaaaggg cgatgaaggg caggtcgagt
    23701 tcctcaccaa gggtggtgga agcgacgaca ttttcgatct tgatcgtggc caaatgggtc
    23761 accttcccgt ccttatttat atacccgttt ataaacgttt atggtgatgg ctcagttgta
    23821 gggccgaagg cctaatgccg atcctgccag accgataggt tatccggcac ttacctggac
    23881 ctggctaacc gccaactttt atatatcaac agggatatca tctaaacgtc agacaaatgt
    23941 ataacttttg tcggacacaa tatggtcagg gctgagtcat gagcgacagc gagaggataa
    24001 ccgtaaggat ccaagcggag aagctgggag cactgcaagc gcttgtggat ggcggcaagt
    24061 tcccgaccat atccgatgcc atccgagcgg ccattgactc cttcattgag acgaacttca
    24121 ctcccgagca catccagagg gtcacggtgg aactgcccaa ggtgaaggtg atcgagctgg
    24181 agtctctgat cagggacggc gattcggtct ccatcgatga tgccattcgc aacgcggtgc
    24241 gggagtacgt ccgcatgagg ttggacaagg ccatgggcga aatacggtga cctcccgccc
    24301 gtcgcaggag ctgagggatg gggtcgcgct tcgaagggat ggatgagccg gaggtcgagc
    24361 tgcatgagct caacattctg gtcgtcggtt gtggcggagg cgggtgcaac agcatccacc
    24421 gtctcaatct tatagggata gcggcagcca cgaccatcgc catcaatact gaccagaaat
    24481 cgctgaaggc caccgaatgc ccgaaccgac ttctcttagg ggtggagtac accaagggac
    24541 tgggcaccgg cggccgcccg gacattggcg aggagtgcgc cttgaacgcc tcgcccatgc
    24601 tatccaagat attccaggac gccgacctgg tgttcatagt caccgggctg ggcggcggca
    24661 ccgggaccgg ggcgtcaccg gtcgtcgccg acatcgctcg ccgctgcggc gccatggtga
    24721 tttccatcgc caccaccccg ttctccttcg aaggcgccag gcggcggaac atcgccatga
    24781 agggtctgaa aaggctgagg gaggcctcca acagcctcct ggtcctggac aacgaccggc
    24841 ttctggacat cgtggagaac ctgccggtcg atcatggact ggccataata gaccagctga
    24901 tttccgagct catcaagggc acggtggaca tcctgacgac ggcgtccctg atcaatttgg
    24961 acttcgccga tctcaagacc atcatggaac agggcgggat atccaccatc ctatacggcg
    25021 agaacgccga tccggagggc gtcgtccgag acgcgatcaa ctcacccctg ctcgacgtgg
    25081 acatcaaagg cggtactgga gcgctgatcc acatatccgg ggggagcaac ctcaccatga
    25141 ggagggccaa caagatcgtt tccagcataa ccaagatgct ggacgatgag gccaccgtca
    25201 agttcggggt gcgggtggag gaagggatgg agggcaacat ccggatgata gccatcgtca
    25261 ccggcatctc cgaggtggtc gacggaatgc cgaccggagc ccccggggac gacctgggaa
    25321 aggtgctggg caagtacggc ccgtgatcac ttcttcttta tgatcttggc cgcgtcaccg
    25381 aacacgccca tgatggtatg gaactcccag cggctgggca tggccctccc catcatcctt
    25441 cggaacatga tggaggtgcg ttcccggcgg aactggggat agttgatggc atccagcagg
    25501 tcatcgaaga actccagcat cttctccttc tcgtgctcgc tggccttctt aggcgatccg
    25561 acatggacct gcttctggta cagctcgtaa agaacgatgg tggcggcgtg agataagttc
    25621 aatgtcgggt agtcctcgtg ggacggtatg ctcaccagca gatcgcatct ggccagctcg
    25681 tcctgccgca gtccggtgtc ctccggcccg aagaccacgg ccaccttgtc ctccacgtcc
    25741 tccagccgct cggagaactc cctgggggtc aacgggatgc gaatgtagtg cttctccccg
    25801 gcggtgacga tgccgctcgt tccgaccaca tggaagcagt cggcgatggc ctcctcgaag
    25861 ctgctgacca cctgggcctc cttcaggatg taaccggcgt gcttggcccg tttgaacgct
    25921 tcgtcggtaa gctcgcaggg gttcaccatg cacagctcgg tgaagccgaa gttggccatg
    25981 gacctggcga ccgctcccac gttcccgtcg gtacggggtt ccaccagcac gaccttcacc
    26041 tgaggcatgg tatccgggac ggaagacgcg tttatctaat tatcctcgcc caccggaaaa
    26101 gcatttagtc ctctgtccag atatgaccgt catgggcagg gtggcggtca agttcgctta
    26161 cgacggtacc cgtttcatgg gctcccagag gcagcccgga gagcgaacgg cggagagcga
    26221 gctgctcaag gccctgctga agatcggggc cataacctcc gccgaagaga accgcttccg
    26281 ggtggccagc cgcaccgacc gaggggtaag cgccctgggc aacgtcttcg cggtggacac
    26341 cgagttccgg catcaggagc tcctggccgc catcaacgct tcctgtgacg acgtgcactg
    26401 ctacgctctt gccgaggcac caaagaactt ctccccccgt cgcgcccaag gccgatggta
    26461 ccgctaccat ctgccgtacc gcgggcagaa cgtcgagctg atgaacgaag gagcaaagga
    26521 gttcgagggg gagcgcgagt tccggttatt ttgcaagccc gatgggaagg tgacgttaag
    26581 gacgataggg tccgtaacta ttcgacatga cggggagctg atcgtcatcg acattcgggc
    26641 cagggagttc ctgcgcaaca tggtccgccg gatcgtctcc gccctggacc agctgggaca
    26701 gggaagggtg accttggagg atgtccggtc cgccctgcaa ggacgtggta gatcgatggg
    26761 cctggcggac ccggaaggac tggtgctgat ggacatcgac ctcgaattgg attggcaata
    26821 tccgcccacg ggaaggatgg ccgcggcgat agccgaagag gcgcacaagg cccgggtgca
    26881 cctgcgcttc gaggaggcgc ttcaggaaaa agcacggctg gcctccaggc ccccgggtga
    26941 tgatatttaa ccgtgacggt agcatgctcc agcccgattc ttatatgccg gcgtagctcg
    27001 aagacctgtt cccaaaggtg gggagaaggt ctgtggggat cgagggggcg gtggggctcc
    27061 ctcggcatcc cttttttata cggtagacga tggcctaggg atgttgatcg ctttgaccgg
    27121 cactcccgga acgggcaaga gctccgtgtc gctcggactg caggccaagg gctggtgcat
    27181 cctggaggtc aatgacctgg ccaagaggca cggtttgctc aagagcaagg acccgaccag
    27241 ggacagctat gacctggacc tggacgagct gcaggaggcc ctggagaagg aatccttcag
    27301 cgacggagtg ctggtcggtc acctgtccca ccttctggac gtggaccagg tgattgtgct
    27361 ccgctgccac ccgcaggtcc tggccaagcg gctggagacc aggaaatggc ctctggccaa
    27421 gatcagggag aacgccctgg ccgaatcgct ggacatcatt ctggccgagg cggtcgattc
    27481 cgaggtcccg gtattcgaga tcaacaccac cgagatgtcg cttcctgaaa cggaagaggc
    27541 ggtgctttcc atactggccg gggaaaagga aaagtacgcc ataggaaata tcgactggag
    27601 cgaggaggcg ttgaaatggt cctagattcc catcgtggca aggtcgactt cctaatggac
    27661 ccggtggcca aggccatgat caaggtccat cccaatcaca tatcgttcat ggccctggcc
    27721 ctggccgccg tggccggggt gatgctgtac ttctcgttcg ataattgggt gcttctcccg
    27781 atatccgccg tggtggtcct ggtaagtggg ttcttcgacg gcctggatgg gaaggttgcc
    27841 cgtctggccg gcattgccga ccgccgcggg gacttcctgg accacgtgct cgatcgatac
    27901 gccgacatgc tgatgatcgg cggggtcgcc gtgagcgcct ggtgctctcc gtacctggga
    27961 atgatggcct tggtcggggt gttgctcacc agctacatgg gcacccaggc ccaggcggtg
    28021 ggcgccaagc gcatgtacgc cgggatcctc ggccgggccg atcgcatcgt tctctccttc
    28081 ctcatcccgc tggtgcagat ggtcatggtg ctactaggtc acccggacct cgagctgttc
    28141 ggtatccagt tcaatgcctt tgaggtcatg atgttgtggt tcgccgtggt gggcaacctc
    28201 accgccttgc agagggcggt gctgacctac gactggctca ggaaggctta gtggtcttgt
    28261 ccgccttctt gtcccggttc cggtcgtagg agcggatccg gtagtaggtt agcggatggt
    28321 tcacccttct cccgttgcat agctcgtccg gttcgaaaca gaccccgttg gtgcgcatgg
    28381 tggcgcactc cggcggggtg tacttcttcc catagccgtc cccggttatg tgacggacct
    28441 ggtaagcggt cttggattga tcgaagtccg gggaggagca gaacagtttg atgatgtcgt
    28501 ccaccggcat gccgatgaag ctaaggaaac tggctaacgc gaaacggccg gcgtgaggca
    28561 tgttctgtcc cgcttgggcg gtggccacca gcttcttcat gcagggcggg aacttgatta
    28621 tgctgaccgt cccgaacccc tcgtcccggt atttctcctt gtaggcctcc agggccacga
    28681 ttacctcttc caggtccgat ctcaccgcct ccagaagttc gtcgttcacc ggcagcggca
    28741 gctcgtcctc gatcctctcg tccagagcct gttccagcac ccggacgaac ttgttcttct
    28801 ccagaagcac gaaacctctt cgcatgtcct ggttgaccag cttccactcc ggaccgcgca
    28861 gtcccgaggt atagctgaga aaatcggtga agtgcatgct cagggtgccg tcctccaacg
    28921 acgcctcgac ctccagctct ctggccaacg ctatgatcgt ggccaggtcc ttcttcttca
    28981 ggcgctcatt gaaggtcttc gcctccgcca gggcgtagcg acggaccagc gcctcgtccc
    29041 cgatgcagga caccaggatg cgggcgtaag ggtagctcag gatctcctgc accgcctcgt
    29101 cctcggaggt gacggggtta ttagggacgg cgagctcgct cagggcggtg agcacccggg
    29161 accggcctct cctcctggcc tcggctgtga tggtatggcc gatcaggtcc tccaggccca
    29221 gctgccgctc cttgacgaac tgggtggctt ccctcaggaa aggatacagg gctaggtctc
    29281 gaaattccat cggctacacc gcatcggttt gcctgataat tagtgttcgg gacggtcgaa
    29341 gctcaggaag gggagcacgg catcggccac ctggggatcg tccaaggcct ttcggagatc
    29401 gtcaaggccc ttcatggggc gggccaggaa gaggcgggtg gcccgcttcc tgcccagtcc
    29461 cgggagcgct tccagggagg tgatgtggca ttcgttcacc gggagcggat acaccaccgc
    29521 gcttatgctg cggaagccat gaccgaccac cgccacatcg tagaacttct ccagatcgac
    29581 ggggtgaggg ataccgacca gcagcggata tgtcccgatc tgccttccga aggtcacctt
    29641 gccctcgcgc atctcggtgt acaccgaacg aagcaccgtt cccaccggca ccaggcgctc
    29701 cagcaggggg cggtctatct cctccctgat ccggtccttg aagtgcagga actcggtatg
    29761 gctgacggtc ggcgnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    29821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnngtctcc
    29881 atgcccaggg ccaggacgtt tccgggcgtg cagtgcttta ccagcgaaat cagtatcctt
    29941 tccgtctccg cggggtggcg ggccatgacc gccgggttgg cgttgtccac gtgcagaacg
    30001 ttcggggaca gggcggacat gccggagagc aacgattcca gggcctccgg gttcggcctt
    30061 gggcagtcgg tgccgtccag ttcggccttg taggaaatga tgcaggtctg cgagcccagg
    30121 cggaagttga ccacgccgcg ttcccggagg gcgccagctt ccgccactat cgcctccggc
    30181 tcccggaaga ccggacggcc cttgagcggc tcgacgcaga aggaacagcc gccgttcacg
    30241 taacgaacgc aaccgcgata cgtttcgagc tcggcggtca acggctgagg atggtccggg
    30301 tgggagagca cgcaatcggc gcccaacagc atccagcgat cccattcctc gctcccgcgc
    30361 cagcggtcac tggccttacc gctgttcatg agatcatgga ccgccgcggc ggcgtccagg
    30421 taatgcgagt ggtggaacct ctccttgagc accgggtcca gggccgccgg gccgccgaga
    30481 acggtctctc cccggtagcc ctcgatcaac tggaacagct cccggcggga ggccggcatc
    30541 ccccgcaggt atcttccggg aacggacatg ccggatagaa cgaccagcag gtccgagggc
    30601 ggtagtttct tcccgttcct ccactggtcc acggtgatgt aactaggcgt tcccccagca
    30661 tccctcaccg cgccaaagac cgccctgggt agaggatgta tgtaaggggg gacccccagc
    30721 gaccccggct cgtctatgta gccgtcgaat atgagaactt caggcacggt ggctccgtcc
    30781 aaaacaggaa agggatggcc ttggtaggcc tttaaggtga tttcagagca ggcttacctg
    30841 catggtctca acgttctgga taccaggcac tgcgcggagg gcctcttcca gcttgtcgac
    30901 caaaccgggg gcgtcctcca tgacgaaggc cgcttccagc atcttgaggc caaaggccag
    30961 gggcttgatc tcggtattgg ccaccttgac gttcgccggt attatcgttg ccagcttggc
    31021 tatgagggcc gggaagtcga actcggtgtc ctcgggcatc aacgcgtagg tggcggcgac
    31081 ggttcccatg atgaacacct tatgggccga tgaagccgca cttcttgcat tcgtacttga
    31141 cgctctggtc acggcacttg gcgcagcggc cgatctcctc agcgccgcag atagggcact
    31201 tgaagaaggt gatgccattg cccactagcc gaacaccgca tgagttgcag atcttttcat
    31261 tctccatagg acatcgcttt gtgcgtgatt atagtcctta tataaaaacg tgattggtcg
    31321 gcgccaccgg ccacttcagc ttctgggtgc ccctttacgt tattaccatc attatattgg
    31381 aagcataggt ttggagcatg gacagcgctt tatatcctat atatcgtgat attaatcttc
    31441 acggcacacg ttcttataca ttgctttcga taccgtgaaa acagcaggaa caatcggcag
    31501 gtccatgttg atcggcgtgc caacaggact aacgttcctt ggtggatggg aaatgttaaa
    31561 tacaaccagg atttactctc ccgttcacac gccggcactt acttcccaat gggcccgtag
    31621 ctcagctagg taggaccttc ggagacggag cgtccctaga aagagcatct ggcttttaac
    31681 cagttggtcc ggggttcgaa tggtacgcgg tacttccgtg tatgcggaaa tccccgcggg
    31741 cccgcttggg taggagaaag aaacatgcag accgaagtat ccaaacccga tttccaaatc
    31801 gtttttagta agtcattact tagccgagga acgacccggt ttctgcatcg tatgaggtga
    31861 ttcgtttgga tgattccgtc ccatttaacg tattaaagca catgatggtg cctagacacg
    31921 agcttttgag cgatgaggag accgacaagg ttctcaagcg gctcaagata acccgcgacc
    31981 agctgcccaa gataaaggac actgacgcgg cgatcaagac actaaaggcg gccatgaaca
    32041 gggacatccc tgagaagagc gtcgtcagga tcattaggga cagtcagacg tccgagacgg
    32101 cggagatatt ccgcctcgtc ataagagggt gaacttattg agggacctcg tcgaactgta
    32161 tttcagagag agcagcatag tcaaccatca tatagccagt ttcaatgatt ttctgtcatc
    32221 ccagagcaat cctaacagca ggatgcagaa gatcgtggac aacgtgaggg tgtccgccga
    32281 ggaccccgag cggggcatga tcacgctgga cccggagaag accaatggcc gcataatcca
    32341 gatccgcgtc ggtcgccgac gggacgagaa gaccggccag gtcgaccagc acctgccccc
    32401 caccctcaag atcggtgagc ccatggtccg cgaggccaac ggtcacaccc acaacatcac
    32461 ccccatggag gccaggctca ggaacctgaa ctacatagcc cccatgcaca tggacgtcac
    32521 catcatcgag gacggcatcg agagggagga gaagaacatc cacatcggag acctccccat
    32581 catggtcaag tcccggaagt gcaacatctt caaggagaac atggagaagg agtacgacct
    32641 caccgacgag cagtacaacg tcgagctcat gaagaagagc gaggacccca tggacgccgg
    32701 cggttacttc atcatgggcg ggaccgagag ggtcctcatc accttggagg acctagcccc
    32761 gaaccgggtc atggtcgagc tcagcgagag gtacggcacc gccatggagg tggccaaggt
    32821 attctcgcag aaggaaggcc accgcgccct caccctggtg gagaagaagc gcgacggcat
    32881 gctcatggtc accgttcccg ccgcctccgg gcagataccc ctggtggcct tgatgaaggc
    32941 cctggggatg gaggatgacc agcagatcta cgaggccata gtctcctccc cggagatggc
    33001 caacatagtt tacgctaacc tggaagagat ccaggacgcc aagctgtacg gtcccaacgg
    33061 catattcacc accgaccacg ccctgaccta cctggagaag aagttcgcca ccggtcaggc
    33121 caaggaatac cgggtcaaga aggtcgagtc cataatcgac cgctccctgc tgccccacct
    33181 cggcgatgtc gaggaggacc gcatgaagaa ggccatcttc ctgggcagga tagccaggtc
    33241 cgtactcgag ctttccctgg gaaagcgcaa ggaggacgac aaggaccact acgccaacaa
    33301 gcgcctcaag ctgtccgggg acctcatgga ggacctgttc cgggtatcct tcaccaacct
    33361 ggtgaaggac atgaagtacc agctggagag gtcctacgcc aggcgcaagg acctggtggt
    33421 caagagctcc atccggccgg acctgatgac ccaccgcctg cagcacgccc tggccaccgg
    33481 taactgggtg ggtgggcgag ccggcgtgag ccagctactg gaccgcacgt ccaacatggg
    33541 taccatctct cacctgagga gggtcacttc ctcacttacc cgaagccagc ctcacttcga
    33601 agcgcgtgac ctgcacccca cccaatgggg tcggctctgt ccgaacgaga cccccgaggg
    33661 tcagaactgc ggactggtca agaacgccgc cctgatcatc aacgtctccg agggcttccg
    33721 cgaggaggac gtcaccttcc tgctgaagga cctggggata cacgaggtca agggccagca
    33781 gatggcaggt acccgcgtct acgtgaacgg cgacctgaag ggcgtgcacg accacgccct
    33841 ggacctggta aaccagatga ggaaccgccg ccgcaccggt ctgctctcgg acgagatcaa
    33901 catccgctac gacgcggaga tggacgaggt catcatcaac tgcgacgagg gtcgcctccg
    33961 ccgggcactg ctggtgctca aggacgggca cctcatgatc acccgcaagc acctggagga
    34021 catacgggcc ggcaagctgc gctggtccga cctggtgcgc gagggtatac tggaatggat
    34081 cgacgccgag gaggaggagg acaccttcgt ctccgtggag ccttacgagg ttccgctccg
    34141 atgcggcaac tgcgaccggg acatctcccc gctggacatg gactggatga accccgggac
    34201 caccgacagg caggccgagc tgaagtgccg gcactgcggc ggtacgacca aggtcgacta
    34261 cctgttcgac aaggcccaca cccacatgga ggtggacccc atggtcatcc tgggtgtctg
    34321 cgccggaatg gttccctacc ccgagcacaa ctcgtctccc cgtgtcacca tgggagcggg
    34381 tatggccaag cagtcgttgg gactcgcttc cagcaactac cgcaagcgcc ccgacacccg
    34441 cgggcatatc ctgcactatc cgcagaagcc gatggtccag accaagttca tggacttcgt
    34501 ggccttcaac cagcgcccgg ccgggcagaa cttcgtggtg gcagtactat cgtatcacgg
    34561 ctacaacatg gaagatgcgc tgatcctcaa ccagagcagc gtgcagcgcg gtctggggcg
    34621 atcgaccttc atgcgaacgt accgcacgga agagcggcgc taccctggag gtcaggagga
    34681 ccacttcgag ataccgtccc ctgacgtgcg cggcgcccgt accgattccg cgtacaacaa
    34741 cctgtccgag gaggacgggc tgatctcgcc agagaccccg gtctccggcg gtcacgtcct
    34801 ggtcggaaag acctccccgc cccgtttcgt ggaggaggag gaagctaact tcctttcggg
    34861 tcacaagagg cgcgagactt cggtcaccgt ccgttccgga gagaccggct gggtggacag
    34921 cgtaatgctc accgagtcgg agaacggctc ccgcctggtg aaggttaagg tgcgcgacga
    34981 gaggataccg gaactggggg acaagttcgc ctccaggcac gggcagaagg gagtggtcgg
    35041 gcttctggtc ccggcctctg acatgccctt caccaccgac ggtatcatcc cggacctggt
    35101 catcaacccc cacgccatac cttcccgtat gaccgtggcc cacgtgctgg agatgatcgg
    35161 cggcaaggtc ggctccctcg agggaaggag cgtcgacggg acggccttca gcggagagcg
    35221 cgaggatgcc ctgcgccaat cgttggtgga cgccggtttc gagaagtccg gccgcgaggt
    35281 catgtacgac ggtctcaccg gccgcatgat acaggccgac gtgttcatcg gcgtgatcta
    35341 ttatcagaaa ctgcaccaca tggtgtccgg gaagatgcac gtcaggtccc gcgggccggt
    35401 gcagatactc accagacagc ctacggaagg ccggtcccgt cagggtggcc tgaggttcgg
    35461 tgagatggag agggactgtc tgatcggaca cggggcggcc atggtcatca aggaccggtt
    35521 gctggacgag tcggacggta ccttccaatg ggtgtgcggc aactccaact gcgggcacat
    35581 cgccatactg gacaagagag gttcgttgcg ctgcccggtg tgcggcaaca acaccaacgt
    35641 gcacatgatc cagacgtcgt acgccttcaa gctgctgctc gatgagctgc tgtcgcttgg
    35701 ggtcgccatg cgcttacaac tggaggattt gagatgatgt caggagtatc caagaggatc
    35761 gggtccatca ggttcgcctg cttgtcgccg gacgagatcc gcaagatgtc ggccatcaag
    35821 atcatcaccg ccgacaccta caacgacgat gggttcccca tcgaccaggg tctcatggac
    35881 acccacctcg gggtcatcga gccggggctg atgtgcaaga cctgcggtca caaggtggac
    35941 gagtgcccgg ggcacttcgg caacatcgac ctggccatgc cggtcattca cgtcggttac
    36001 gtcaaggaga tcaagaagct cctgcaagcg acctgcaaat cctgcggtcg cctggtgctg
    36061 accgaggacg acgtgaagga ataccaggcc cgattggaca ccatggagga gctgggcagc
    36121 gacgccatcg atctccggga gttcgccaag gagacggcca aggcagcagc ggtaaaggcc
    36181 accaaagagg tctgcccgca ctgcggcgtc gagcagctca agatcaccct ggacaagccg
    36241 accaccttcc gggaggaggg ccacaagctc actccgaagg aggtaaggga gcgcctggag
    36301 cggatacctg acaacgacct cataccgttg ggaatagacc cccacgcctg ccgcccggaa
    36361 tggatggtgc tcacggcatt gccggtaccc ccggtgaccg tacggccgtc catcactttg
    36421 gagtccggcg accggtccga ggacgatcta actcacaagc tggtggatgt tctcaggatc
    36481 aaccagagat tgcgagagaa ccgcgacgcg ggagctccgc agctcatcgt ggaggacctc
    36541 tgggagctgc tgcagtacca cgtcaccacc tattacgaca atcagacctc gggcatcccg
    36601 ccggccaggc accgcagcgg acgcccgctg aagaccctgg tgcagaggct gaagggcaag
    36661 gaaggccgct tccgttccaa cctgtccggt aagcgcgtca acttctcggc ccgtaccgtg
    36721 gtctctccgg acccgtggtt gtccatcaac caggtcggcg tgccgacctt cgccgcccgc
    36781 gaactgaccg tgccggtcat ggtcaccaag gacaacctgg agatcctgcg caacatggtc
    36841 aagcgcggcc ccgagcccgt tggggaggtt tatgctcccg gggtcaacta catcatacgc
    36901 atagacggcc gccggatacg cgtcaccgag aagaacgcgg agacggtatc cgaaggactg
    36961 gagatcggct acaaggtgga aaggcacctc atggacggcg acgtggtgct gttcaacagg
    37021 cagccctcgt tgcaccgcat gtccatgatg gcccacgtgg tcaaggtcat gcccggaaag
    37081 accttccgct tgaacctctg cgtctgtccc ccgtacaacg ccgacttcga tggcgatgag
    37141 atgaacctgc acgtattgca gagcgaggag gctcgcgcgg aagcgcacat cctgatgaag
    37201 gtgcaggagc acatcctgtc cccccgtttc ggcggaccga tcatcggcgc catacacgac
    37261 cacatcaccg gtgtgttcca gctgacgtac aagaaccccc acttcgataa ggcgcagacc
    37321 ttgttcatcg tgtccaagat gggcgagaac actctgcccg agccaatcat cgagggtggc
    37381 aaggagatgt ggaccggcaa ggacctgttc tcgacgatat tgccgaagga cttcaacgcc
    37441 cagttcaagt ctcacatctg catgaagtgc ccgaagtgtg agaaggaagg atgtcagtat
    37501 gacgcctacg tcaagatccg tgacggaaag gtgctcatgg gcaccatcga cgacaacgcc
    37561 atcggttccg gcggcggcaa gatactggac aagatcgcca gggactacgg cgccgaccgc
    37621 gcccgggagt tcctggacga cgtgaccaga ctggccatcg gggccatcat ggtcaaggga
    37681 ttctccaccg gtatcgacga tgaggatatt cctgaggaag cgaagaggca gatagacgac
    37741 aagatcaaca acaccttcca ggaggtcgac aagctggtag cgtcctatag ggacggtacc
    37801 ttggaccaga tgcctgggcg ttctctcgag gagaccctgg aggtggaggc gatgaagaag
    37861 ctgggtgagg ccagggatga agctggacgc atagccggga agcacctggg tatcagcaac
    37921 gcggccgtgc agatggccaa gtccggtgct cgcggctcca tgcttaacct gtcgcagatg
    37981 gccggatgca tcggtcaaca ggccgtgcgt ggcgaacgtc tctccagggg atactggaac
    38041 cggacgctgc cgcacttcca gcagggagac ctgggggctc aggccaaggg gttcgtcaag
    38101 aactcctaca agagcggtct gacgccaacc gagttcttct tccactccat gggtggacgc
    38161 gaaggtctgg tcgatactgc cgttcgtacc tcccgttccg gttacatgca gcgccggttg
    38221 atcaacgccc tggaggacct caagctgaag caggacggta ccgtccgcaa caccgcggac
    38281 agcatcatcc agttccatta cggcgaggat ggtgtcgacc cgacgcgcag cgtgcagggc
    38341 gaggcgatcg acctggacga cgtcctcagg gacgtcctgg gcgagcatta cgccgatttg
    38401 ctgtccagac cggacgagcg caagatcagc ctctacgcca ccgtggagaa ggacctcatg
    38461 gaggccgcca cggacgagga cgacgagacc gaggaagccg atctagacat cggaggtgat
    38521 gagtgatggc ccagaaggat ttcatcaacg cgctggaaaa gaaaggggtc cccatggaca
    38581 ccatcgacat cgtcaaggag aagtacacca accagaccga cctggtaaag gcgtccgtct
    38641 ccgacctggt ggagctcggc ctggataagg aggccgccga ggacctgcag accaagctgg
    38701 gcaagaagga gaagcccacc cgggccccgg ccaaggccaa gaccggctcc cgccggaagg
    38761 tggagaagaa tcagcccgag gccgccgcgc cggtggtcta cgagatcccg gacaagagca
    38821 agaagtactc gcctttcgag gaccagctct tcaagaagtg cgaggagctc aagctgcgcc
    38881 tgccccgccg ggtgatactc aacatcgccc atcgcctgga agggaacgac ataagcaagg
    38941 agaacctggt aaagatcctg aaggtggcca accaaaagta ttccgaccac ctgatggacc
    39001 ccaacgagag cgctggaata ttggccgcgc agagcatagg cgaaccgggt acccagatga
    39061 ccatgcgtac cttccactac gccggtgtgg ccgagatcaa cgtcaccttg ggtctgccgc
    39121 gtctcatcga gatcgtggac gcccgccgca tcccgagcac tccgatgatg accctgtacg
    39181 tcaacaagga gctgtcgagc gacgtggaca ccgtcaagaa catcgcctcc aacatcgaga
    39241 taaccaccgt gctggacctg gccgatatcg agacggacct gcataatctg cgattgttca
    39301 tcgtcccgga ccagaggaag tgcctgcaga aggggcttct ggaccaggac ggaagaccgg
    39361 tccggggaca ggtggccccc atcgaaatga tcagggacaa ggtctcccgc ctgcggggta
    39421 tcgtcatggt cgacgacatc gacaaggaat cgctaccgcc gaaggtggag ctggccggcg
    39481 aggccgggat cggatacttg tgcctggtgc cgaaggaacc gtccttcaag accttgcaga
    39541 aggccctgga catggtcaag gtggccaagg tcaagggggt agagggcatc acccgcgccc
    39601 tgctcaagaa gaaggatgac cagtgggtca tattcactga gggcagcaac ctgcgggaag
    39661 tgctgaagat agacggactg gaccattccc aggcctacac caactccata caggaggtca
    39721 acgaggtgct gggggtggag gcggcgcgca actccataat cgcggaggcg tcccataccc
    39781 tggacgaaca gggtctgtcc gtggacatac gccacatcat gctggtggcg gacctgatga
    39841 ccgctgacgg ggacgtcaag gccatcggcc gacacggtat atctggaagg aaatcgtcgg
    39901 tgctggccag ggcggccttc gaaataaccg ccgcccacct gctcaccgca gccatgaccg
    39961 gggaggaaga ccacctggac ggcgtggcag aaaacattat agtcgggcag ccggttacac
    40021 tcggaaccgg ggccgtaaat ctcgtgtacg cacctgtaaa gaagggggca tctgaatgat
    40081 cgatctggga agagccttaa aatctgccat gaccactgga aaggtggtct tcggcgtagc
    40141 gcagtcggaa aagacagtta ggaacgggga ggccaagctc gttatcgtgg ccaagaactg
    40201 ccccagcggc tacctggtct ccaaggacca cggcgtgccg gtgtttcagt tcgagggaac
    40261 caacatggag ctcggcgccc tgtgcggaaa gcctttctcg gtgtcctcca ttgccgtaat
    40321 cgacaaggga gcatcaaaca tactttcgct gggttgaaca tgaccgctga catcaccttt
    40381 accgaggaga ccctgcgcta catcagcctg ttcgagaaga tcaccaaggc ccgggtccgc
    40441 gattgcatgg agaccgagga gaagctcgtc tacgtcgttg atccaggcca ggccaaccgc
    40501 gcggtcggca aggcaggcga gaacgtgatc aagctcaaga acaccaccgg caagaacatc
    40561 caggtcgtgg agttctccga cgacgcggag acgttcatca agaacgtatt ctacaactac
    40621 ggaccggaga aggtggagat cgagacccgc ggcaccatcg ttcacgctac cgtcaccgtc
    40681 gatccggccg taaaaggtcg ggccatcggc aagaacggca agaacctgaa gatagcccgg
    40741 gacctggtca accggcacca caacgtgcag agcatctcgg tggcctagtt cagcggttgc
    40801 cgttccacct ctagccggtc cgcggtcggg tattcctcga ccagatagca gcggtaaggc
    40861 agagcggcgg ccagttcctc caacacccag agggccacct ccaacctctt tctcttttca
    40921 tcccatccga acagctcgga cggtacttcc tgttcctcca acgaacgaac ggcctcctcc
    40981 ggccggtccg tctcgattat tccgagcagc accatcccct ccgaggtgat caggtccctg
    41041 ggcctcgccg tccgcttggc ccttctttta agacgttcgc ggagctgcac ctggtccttg
    41101 aagctggagg agcagaagtg caccggaacc atgtcaccag cctcctccat cacctgccag
    41161 gaggtctcca tgctcccctg catggcgctc gatacgtccg aacggacatg gaagttccgg
    41221 ccgagcagcg cctggcaatt ggtctcggac acctccagct cgttcaggtt cacgaagtcc
    41281 aggccgatat cggcggcctg ccggcatatc gacagtaatc ctttcagctc tccggggacc
    41341 gccggaactt cgaatcctac cttcatctcc aggccttgga cggcctcggc gatgcccagt
    41401 tcctccaacg aaccccagcg ctcgatcggg ggatgcatcc tcagctcgtc cagcccggcc
    41461 tcctgcagcc tcaggaactt ctcgcggtcg atggttgatg tgtacaggtg gatgtgatgc
    41521 cccggtccga agcgctgctt cagcagacgg atgtaccgtt gcgtacgttc catgaccagc
    41581 agcgggtctc caccggttat ccccgttccc ttggcaccga tggcctccgc ctccctgatc
    41641 aggtcctcgt ccttacttac cagtagctcg ttggcgtaca ccacgtcctt tcccttcttc
    41701 gcctccgaca gagggcaata atagcacgat tcgccgcact tgccagtgac caggagcacc
    41761 atcttgcttc cctttcggca caggcggcat cctcgcgata gccgtttagt gtagcaggac
    41821 gacgattcca tggggatggg gcgcatggca cctctaccgt cccgggcgga cttaacgctt
    41881 gctcatggca aaatcctaaa tcggcgagga acgttggcat cagggatagc atgaggaagc
    41941 aaagccgggt catacttgcg ctggacgagg tgcgtcccga gaaggcgttc caggtcgcgg
    42001 aacaggtgca cgacctggtg gacgccatca agatcaactg gccattggta ctggcgacgt
    42061 ccccggagac cataacccgg ctgtcgaaga tggccccggt catatgcgac ttcaaggtgg
    42121 ccgacattcc caacaccgta tcgctcatag tatcgcaagc ggtgcagcgc ggtgcggaag
    42181 gcgtcatcgt gcacgggttc accggaagcg attcggtgaa ggcggcggtg gcggccgctg
    42241 acggacgcaa gatattcgtg gtcaccgaga tgtcccatcc cggcggggcc gagtataccg
    42301 ccccggccgc cgaatccttg gccaagatgg ccgttgattg tggcgcggcc gggatcatcg
    42361 ccccggccac ccgaccggag agggtggcgg tcctgagaag gatcgttggc gacctgctga
    42421 tcctttcccc gggagttggc gcccagggcg gaagcgcctc ggcgaccttg gacaaagggg
    42481 cggattacgt catcgtagga cgaagcatct acggggcgga ggacccccgt tccgcagctt
    42541 tgcaggtggt taaagaggcc cagggcgccc attcccgatg aggcgaaata tcggttccgg
    42601 cgtggttagc cagatgtctc tttttatagg cctgggtcgg accaacgtat ttatacgggg
    42661 tgcgttatca gttgctaatc accccagagg agactaacta atggcaacga agcaggaggg
    42721 gtccagtcaa cctactgaca agcagcgctc tctttcgttg tccaatttct ctcgtgacct
    42781 caaggattct tggatcggaa gaaattggca gaccgtgctg ttgctggcaa tgatggtgtt
    42841 cctggccttg ttcgtcagga gctatttcgg attttccacc tcggtggaca atggctacct
    42901 ggtctcaggt ggctctgact cttactatca catgagggtc atcgatcacg cggtggcaac
    42961 tggggaccac ctggtgtggg atgacatgct caactatccc aatggaatga ggaaccctcg
    43021 cccgccgctc tatgactggt cagtagcggt ggtcggaatg ctcctcagca ccgttaccgg
    43081 tctggcggta aaggatgcca tcggtatgtc gctagtgttc tccaccgcgg tgtggggcgc
    43141 gctaaccgtg gtcccagttt acatgctggg cagggcggcc ttcggtcgta aggccggtat
    43201 gctaggggcg ttcatattcg ccctcatggc cggccatatc gaacgtacgg tgctgtccaa
    43261 cgccgaccac gacgccatag tgctgttctt cgtggtgttc tcgttctact tcctgttgcg
    43321 ttcgctgcaa tcggtgaacg ggagtcgctg ggtatccaaa tggaccgatc ccaaggccat
    43381 attgccaggt ctgaaaagtt acctgcgcac caatcagttg tcgctcatat acgccgccct
    43441 gggcggacta tgcgtggcgg ccgtcggcct catctggacc ggttacacct acctgctgat
    43501 cgtcgtcttc gtctacttca tcgttcagct gctggtcgat cgcttccgca acgccgattc
    43561 catgggcgtg ctcattgccg tagccgcctt cttcggcatt gccttcctgg tgatggcccc
    43621 ggcctatgtg agccttaacc tcatcgtcac ctggttcgac accccgctgt ccctcttcgc
    43681 catcggcatg gtgggcggac tcatgttcgt ggtcacccgc gattacccgt ggaccctggt
    43741 gctgccggtg ttcaccgcaa tactgttggc ggccctggcc ctgctatccg tattcaaccc
    43801 ggcccttctg gactccataa tgtccggtca ggggtacttg gtcaagagca agctgtacga
    43861 caccatctcc gaggcccagg ccccgatgtt ctccaacctg gccatgtcct tcggcatggt
    43921 gaccttctgg ctggcgctga taggcgtggg ctacgcggtg gtcaagatac ccaagaacct
    43981 caatccatcc ttcattttcg tggtggtctg ggtggccata tccatctaca tggcctcctc
    44041 ggccgccagg ttcgtgttca acgcctcccc ggccttcgcc gtttcggccg gatggatgct
    44101 cggtctgata attgaccgtc tcaagttcga tggcatgatc cgcggactgc gcaccgacca
    44161 cggcggactg tggaagacca taaggacctc ggtgaagatc cgtcatgtcc tgggagcgtt
    44221 cttcataatc gtgatgatac tggtgcccaa cgtgtggtac gccgtggacg ctggcatacc
    44281 ttcgaccacc aagaacgagt acgacgccca ggtataccac gccatgcccg atttccttcg
    44341 gccggataac tacgatctga agaacgggac caattggtac ctgggagcgt tcagctatgg
    44401 cctgacatta cccaaccaat attggccagt ggcttggaag tggtttgccg cgcaggatac
    44461 cgaaaaggtc gccgccatgg accgtccggc cttcgtgtcc tggtgggact acgggttcga
    44521 agccattcag gaaggcggtc acccagcggt cgccgataac ttccagaacg gttacaattt
    44581 cgccggtacg ttcctcatga cccagaccga ggacggggcc atcgctatgt tcatcatccg
    44641 tagcgtggag tacgatgtct actggaacac cacccagggt caggacaccc tggataagat
    44701 ggccgagtac ggtgtggaca ccgtacgttt caaggacatc atgatgaacc cggccaacta
    44761 cgtggacgag gtgaagaaca atcccgcggt gtacggcgag atcgacgacg atctcagccc
    44821 cgccaacgcc aggtacatag cggccaggca ggttctcact actcttagca aggaccagct
    44881 ggtctcgctg tacaatgatg tgcgcgagat aaccgggaac gacatcggat acgtttccgt
    44941 ggacagtcgt ctgttcccgt tcaccgccac ttcctacaac atattctacg ccccggccaa
    45001 gctttcggac cagcgcgtcg acggtaacaa cattccctac gactactata ccatctacgc
    45061 cgtggacatc tatggggacc agatccccct ggaccaggtc acctcctcta gttatatcac
    45121 cagctacgag atcgtctaca ccgaggcgtt ctacgacacc atgctctatc gggccttcat
    45181 gggctacggt cccagcgaca tcggggagac caagcagggc ctgccgggca tatccggaag
    45241 cttgcagggt tccccgtcca tgcagggctg gaacatgagc aacttccgcc tggtgtaccg
    45301 taccgcatac tacaacccgt actccagcga ggacgtggcc aaccacaccg atgcctggcg
    45361 cgcggtctcc tacgacgaag cgatcagcat gtacaaccgt atccaggcca aggagctgat
    45421 cggtaccgtg gacctgtcgt cgtctggcct ttactccggg gtgaccttcc tgcagtacta
    45481 cgacggtgct atcgtcaaag gtcaggcggt caccgacgcc ggaaggccga tggccgggat
    45541 atgggtgacc gtgctcgacg agtatggtat tcctcatcag gtggtcaaga ccgattcgga
    45601 cggacgatac agcgtcatcg tccccttcgg ggaagtgacc ctggtctatt cctacggtga
    45661 cctggacccc cgtatgctat acggaacgca gctgcactcc gagaaccttg atataacgta
    45721 cgatcaggcc atgcgcgtgg aggccgatgt ggacaagaac gaccagctgg actacctgat
    45781 cgaccttgat gtcgtggtat cggctggctc cctggtcgga caggtgttcc tagacaacga
    45841 cgggaacggc aagtactccg ccgccgcgga tgaagcgctg atcggagcga ccgtaacgtt
    45901 cgcgaacgcc accaatggct tccgggccca ggcgacgtcc acggccgatg gttacgagat
    45961 agcgggcatc agcccgatgt ccggtaccat ctcggtggat tatcagggtc acgtgttcgg
    46021 taccgccagc gtgcaggtcc ggatgggctc cccggtctcc aaggacctct acgtcgagcc
    46081 ggccggaatg aacgggacgg cgacgctggc ggacggcact gccgccggac agataacgat
    46141 atccctattg gaccgcacca acggtcaggt gttcgagtcg atcaccgatt ccaccggcgc
    46201 ctatgctttc gatgggctcc tggccggcaa ttacaccata cagacaccgg acgggaccgc
    46261 catccagagc gctgacgtaa ctctgggagt cggcgactct ctgaccaagg acctggtcct
    46321 ctacaactcc atgcgcctaa gcgggctggt cagttacaac gggaacgcca taagcaatgc
    46381 catggtcggc ctatccggcg acctgggcaa cgtctgggtg cagagcgatt cccgcggaag
    46441 gtattcggtc gtcgttccta aggg
//
LOCUS       DAOPZI010000006        46139 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_645_length_46139_cov_7.853094, whole genome shotgun sequence.
ACCESSION   DAOPZI010000006 DAOPZI010000000
VERSION     DAOPZI010000006.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 46139)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 46139)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46139
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_645_length_46139_cov_7.853094"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..500)
                     /locus_tag="PKM11_02395"
     CDS             complement(<1..500)
                     /locus_tag="PKM11_02395"
                     /inference="COORDINATES: protein motif:HMM:NF021412.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 17 protein"
                     /protein_id="HNX47395.1"
                     /translation="MEFELEGTEQYALESYQWMLERILMEMGISTMVERVRLLIRPDQ
                     TLFIISMRVKQSGSKRPVYDIADMESQEGGTFVTIKDESYAPRLLASLWRLYGRERVQ
                     QLTRLEIFVEGVPKEDLSDMKLDPEEEVRSQLLDAMWRLLPEGLKLRNEYFNDNVMTI
                     VATEHG"
     gene            complement(508..1731)
                     /locus_tag="PKM11_02400"
     CDS             complement(508..1731)
                     /locus_tag="PKM11_02400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 15 protein"
                     /protein_id="HNX47396.1"
                     /translation="MIKIAQLSCGTEYSAVQAEIEHAAETVGAKMVYPDVDMNKIDKA
                     VDEFGFNPNSPQLKLMIARAIELADKNYDADAIFIATCFRCAEGALVRTELRKFVQEH
                     VRLPVVTYSFTERTKAAQLLTRMEALVTIVERKELLARERQVGLTAGLDSGSSTTKAV
                     IMRDNQIIGKYWLPTTDVYSSAETALTNALAEAGVKFEQLEGIGTTGYGRFTLGKKFN
                     AKLVQEELTVNSKGAVWLAGKQKGEATIIDIGGMDNKAITVRDGIPDNFTMGGICAGA
                     SGRFLEMTAKRLKVEITELGELADQGDHGKVKMNSYCSVFGIQDLVTSLAAGNTLADV
                     ASAACHSVAEQIYEQQLQEIEVRQPIIQVGGTSLISGLVTAMEHTLGHRPIVPKDSQY
                     IGAVGGALLVSGLLG"
     gene            complement(1728..2162)
                     /locus_tag="PKM11_02405"
     CDS             complement(1728..2162)
                     /locus_tag="PKM11_02405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 5 protein"
                     /protein_id="HNX47397.1"
                     /translation="MKIFIMPPNSLILFDLVERFGHEPLSLMKALRDRVTSNEIEAPP
                     LNVTLDDVKTGLKYAGIEIPSGIRGRLAIYGPLIDQAEAAIFMEDAPYSFGCVGCQRT
                     NELAKLLVRKRKVPILSLDYPANEDDAKDMVVRVKEFLEGLK"
     gene            complement(2159..2584)
                     /locus_tag="PKM11_02410"
     CDS             complement(2159..2584)
                     /locus_tag="PKM11_02410"
                     /inference="COORDINATES: protein motif:HMM:NF021401.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker protein 6"
                     /protein_id="HNX47398.1"
                     /translation="MDSNIETRLIFIAPTSDLTPDRIARFIHNLGNEISVKETCYGVV
                     LQGPKDAVKRTLDEVRKMDPNRIYSKIRAFPMGDLRRCRAHHGSRPGFAQLEKEWKDL
                     CLVEQGLICVEKGEKPPTPKKRQKIPVNDLRKLIDEVSP"
     gene            complement(2586..4247)
                     /locus_tag="PKM11_02415"
     CDS             complement(2586..4247)
                     /locus_tag="PKM11_02415"
                     /inference="COORDINATES: protein motif:HMM:TIGR03268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 3 protein"
                     /protein_id="HNX47399.1"
                     /translation="MRAVVNGKEKELPEGATVAQAIVGEPYVAGSSVALIRPMDAQRK
                     LTNEYMVKTPRGCFIIELNGSKFAEAWKRLYHDVVGKNLRWQTSRLHAFGAFPTELEK
                     SRGTSSYKRYDCLFALGGYDVNTTYFMIARVDMSDDLGLKDAVFGRVTRGRHILDMLD
                     EGDIIEHIEPVVLRMTSQDAFSVTDLDVPVEDGMLIETFVGVKLDDRSPLCCEHFLVV
                     TSEGSLPIDEKGFSYTASEANMDTSLGQEYTNVRHPDTVTVRHKGYQVGKIFFYNQVR
                     QLNRSHNIVGQVTNGHNLVHLVPLKGRVLVQPDPLRIMTIGKTQAEAQRFLESIGKVQ
                     KRTGDASDDAMIVEQEPEMTIYASKEKEIETMGVPKEKVFPITMDPDRSPWTVRYFRK
                     VTGMDHKPIGTMKVHFTFEGMPMITFEGDPKLAADLYPEKTFEGRSVRGDIGITNMSR
                     PQRGLIGIRLEESEEFGPTGEETPGTSILGRFIGDLDDMMSGISEGDIIYVRRATPEE
                     SVLKKAKRPTKAKSGSEEQKKPAKAKAPAAKKAKSSAKRSKPKED"
     gene            4372..4965
                     /locus_tag="PKM11_02420"
     CDS             4372..4965
                     /locus_tag="PKM11_02420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47400.1"
                     /translation="MNSRKTLNTNVDRDAIRSAVRERMLALVGIEAVEYLDQNFRQEI
                     EERERAAEANGAVGGLMAFVNTGVWEVLSRQEVLVIVAQPKVAILSPQDHLVHIVDQK
                     GQVIGEYLPEGRRDEVELRENAYLLSEDFVLYGDVDMAGEPYFLIPPMPFPPLADMDG
                     IKKLVSASISTISDDHIRERLGYYDTKCWTHLIGYDI"
     gene            complement(4962..5567)
                     /gene="mcrC"
                     /locus_tag="PKM11_02425"
     CDS             complement(4962..5567)
                     /gene="mcrC"
                     /locus_tag="PKM11_02425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-coenzyme M reductase I operon protein C"
                     /protein_id="HNX47401.1"
                     /translation="MKDSIGRKTRFVECREARGMGVGGSLAQRATISDSGRDVVAVAM
                     GPGKRHITKPVCEITYGLREEGIDTSVIVITAGSGVPSDAVDVSTSSLFGLDPIEVAR
                     IQQFKVALIHLGNVRNHIIYKARLILRNVDLPAVICCQAPVDFEDFARIGCKTRLVMP
                     KEEDIGTKGTIMEIVTGVVRGTTVSQVKLDEIVAKVKKTMP"
     gene            complement(5570..7192)
                     /gene="atwA"
                     /locus_tag="PKM11_02430"
     CDS             complement(5570..7192)
                     /gene="atwA"
                     /locus_tag="PKM11_02430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl coenzyme M reductase system, component
                     A2"
                     /protein_id="HNX47402.1"
                     /translation="MAQGSEVFIILDKVSKSFNGNQVLKDISTTVRTGEVLGLIGKSG
                     SGKSVLIHAMRGNEEYKPDSGRIIYRVNHCESCGWVDMPSPGAKCSQCGKGTKIVEID
                     FWGLKERDPLRVAMRARIAIMLQRTFALYGDLSVIENVFEAMKEKSDDKKVARAIKLL
                     EMVNMTYRTMHIARDLSGGEKQRTVLARQLAREPLLFLADEPTGTLDPETADTVHKAL
                     IKAVEETGMTMVVTSHWPKAIELLSHRAIWLEDGKIKAEGAPCDIAKEFDVKVVRDKK
                     MDVQVGQPVIRVDGAKKYFYSIVRGVVRAVDDVSFEVNEKEIFGLIGLSGAGKTTLSR
                     MISGITPATHGDVEVRIGDDWVNMSDMGEEGRGRATQYIGIMHQENALYPFNTVLQNL
                     TICLGMKLPQELAKMKAIQVMRGVGFTAKEVERILYAYPDALSVGEKQRIALARTLII
                     EPRFVVLDEPTGTMDPITRQAVAKSVLHARKELSETFLIVSHDMDFILACCDRVGLMK
                     GGKMIMIGTPQEVLKGFSQEDLDGDESDVCGV"
     gene            7310..8266
                     /locus_tag="PKM11_02435"
     CDS             7310..8266
                     /locus_tag="PKM11_02435"
                     /inference="COORDINATES: protein motif:HMM:NF021410.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2111 domain-containing protein"
                     /protein_id="HNX47403.1"
                     /translation="MSFSSYFAGGPTPKFNAYHIWKAHQVVAKEGPIGRKALAELLQI
                     GEGSTRTILDKMMREGSIESSRLGITITERGKRKLDTSGVEVRQIDLSDLTLGKYNCA
                     VLIKGSAERVHLGCEQRDEAVRAGAVGATTLVVSNSRIVFPGDEEFPDQSLVAPLKNY
                     FRMDDGDVIIIGSAFNYEAAEKGAVTAALSLSNISRRCWNEGTSILSQDTEADDLRCL
                     ALAIHELLGRLPVTMRSKNHPGVRCEEGEIIDTRFTGPMLEESMKKGMIIRRTSISGP
                     YRGMPVIAVPIMRKKEAIACIATMDLGKGTPSELLTRLAERS"
     gene            complement(8263..10089)
                     /locus_tag="PKM11_02440"
     CDS             complement(8263..10089)
                     /locus_tag="PKM11_02440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KamA family radical SAM protein"
                     /protein_id="HNX47404.1"
                     /translation="MRNTKTPARGSSETGRKMKDIGQALLWASDPQMHEALSSADDVR
                     SARSAMFDLLKERETELHSRNCHLHALERSNSLHSIRVMRNFLSPRNERVSGVSVMEN
                     LFNLSHGSVNDVRQAFVSDIMHIMKGTTGQPVLELQEAPDFSTLGGKEGGRLRSDYLD
                     GMAGAVKEWTDEYPSGLEPLVIKKRVENRNRILDYLGATSDDWGDYVWHTKNIMLSPE
                     VIGDLIELTDDEREAISLCVTNRIPFGITPYYLPLMDREPSRKWDHAVRAQVIPPLSY
                     VQAILRSRNDPSANLDFMMEGQTSPVDLVTRRYPMIAIFKPYNTCAQICVYCQRNWEI
                     EGVLSEDAMAPPEKIEAALEWFADHPLVSEVLITGGDPAMLSNTYLRSLLGRLADIPH
                     IKRLRLGTRVPVVLPMRMDAGFLDTISDMHDPPGREFALVTHFEHSYEVTPEAANAVR
                     SLRSLGISVYNQQVFTMENCRRFETVALRTVLKEIGVDPYYTFNAKGKEETSEYRVPI
                     ARLLQEHKEEARMIPGLSRTDEPVFNIPALGKNHLRAWQHHDLISLTPRGERVYEFHP
                     WEKNIAVASMYVHQDVPIADFLTALVERGEDPSQYRSIWYYF"
     gene            10232..10573
                     /locus_tag="PKM11_02445"
     CDS             10232..10573
                     /locus_tag="PKM11_02445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47405.1"
                     /translation="MSDETELTLQATVKVDPGVCRLPSTIQARTDGMIVEFEILHSDC
                     PHVRNLKKMLKQMEIWDIMKMPYAENTIYQICGEALKHSSCPVPMAMIKCAEAAAELA
                     LKKTVTVEFVP"
     gene            complement(10574..10867)
                     /locus_tag="PKM11_02450"
     CDS             complement(10574..10867)
                     /locus_tag="PKM11_02450"
                     /inference="COORDINATES: protein motif:HMM:NF014664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HNX47406.1"
                     /translation="MSLEQMAEQQPEVIRAMYRFKNEVFKDNKLSFKEKELIAVAVTA
                     VLKCDECFRLHSKKAMEAGATKDEIRESLFVAMYLAGPSAAVGMPSIDQLLSE"
     gene            10947..11489
                     /locus_tag="PKM11_02455"
     CDS             10947..11489
                     /locus_tag="PKM11_02455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47407.1"
                     /translation="MQPEERAVEIIKGMTGTQKAFLLPRDVITAVQKIEDSIKSQIGL
                     DVVNEGVNQCLRRQHVICVIKDTRFRPPPEPTVLMMGDSDLVIGTEVLPGQHSLFKDR
                     DNTCWLGDDFVVFTDKVPKTKEFFLMPPVSFPELEQVAGAVNIVSCSPSPLGDLVIKN
                     YYELEDNPKLASILVGFDLS"
     gene            complement(11578..11844)
                     /locus_tag="PKM11_02460"
     CDS             complement(11578..11844)
                     /locus_tag="PKM11_02460"
                     /inference="COORDINATES: protein motif:HMM:NF021397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2098 family protein"
                     /protein_id="HNX47408.1"
                     /translation="MQVGDYAKYRVTGTVGKVLEVLDRNGVEWALLDTYNLWYVSSNL
                     DPASASEYKRTSYKERTRVVLGEFQGLTEDVEADISTLTPSGGG"
     gene            complement(11853..>13495)
                     /gene="mcrA"
                     /locus_tag="PKM11_02465"
     CDS             complement(11853..>13495)
                     /gene="mcrA"
                     /locus_tag="PKM11_02465"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     alpha"
                     /protein_id="HNX47409.1"
                     /translation="FIAAMHKKFKEDPTEVRSKHYSYGGWRQSKRKREWVEQSNKIAK
                     ARGIPMMNQDVGVALGQRVLMPYQLSHTDIYGEADDLHWVNNAAMQQCWDDIRRTVIV
                     GLDVAHNVIEKRLSKEVTPETINRYLEAVNHTMPGGAVVQEHMAELCPELVKDSYVKV
                     FSGDDELIDEIDKCFVIDINKEFPADQAKQLKAAVGKKLWQVVRVPSIIGRVCDGGTI
                     SRHSAMQISMAFITAYRLAAGEAAIADFAFAAKHAAVVEMGTMMPARRARSPNEPGGI
                     PFGVLADMVQSTRTKPDDPARASLEAVALGAVVLDQIYLGSYMSGGVGFTQYATAAYT
                     DNILEDYTYWAVDHIKDKYGGYCKSKPSSELIEKLGTEINSYALEMYERYPAAMEAHF
                     GGSQRATVAAAATGIGIAFATGNANAGVNGWYLSMYQHRERLGRLGFYGYDLQDNCGA
                     SNSFSYRSDEGLPHELRGPNFPNYAMNVGHLSGYTGIAMAPHAARGDAYVCNPLVKIA
                     FADKNLPFDWANITKEFGRGCLREFVPMGERTAIIPAK"
     assembly_gap    13496..13595
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<13596..14045)
                     /gene="mcrG"
                     /locus_tag="PKM11_02470"
     CDS             complement(<13596..14045)
                     /gene="mcrG"
                     /locus_tag="PKM11_02470"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     gamma"
                     /protein_id="HNX47410.1"
                     /translation="MAKTKYKAQFYPGNTLPAKNRRRFMDPSVKLEKLRDVPMDDVVK
                     ILGHRVPGSDYATIHPPLAEGSEPDCPIRALVEPIEGAKKGDRIRYVQFTDSVYWAPI
                     IPYVRAQMYMWRFRGIDTGTLSGRQIIEMRERDVEKVAKELIDGETFD"
     gene            complement(14047..14469)
                     /gene="mcrD"
                     /locus_tag="PKM11_02475"
     CDS             complement(14047..14469)
                     /gene="mcrD"
                     /locus_tag="PKM11_02475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-coenzyme M reductase operon protein D"
                     /protein_id="HNX47411.1"
                     /translation="MSTPASEGVPLPEIQIFPERLLSASTTEVLLNKLYTVKNVRQIN
                     IQGEGLPTVMKAGPGTGGPVNHPERKKIKVRGEDVELTVQVGRIFVEISDIDFVPQAL
                     KDVEEVCKEVLPFSFTLEVGRYNKFKPTTSDFKKGLVK"
     gene            complement(14472..15800)
                     /gene="mcrB"
                     /locus_tag="PKM11_02480"
     CDS             complement(14472..15800)
                     /gene="mcrB"
                     /locus_tag="PKM11_02480"
                     /EC_number="2.8.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme-B sulfoethylthiotransferase subunit
                     beta"
                     /protein_id="HNX47412.1"
                     /translation="MAKYKDKVDLYDDRGKIIEKDVPLDALSPLNNAAIKRTISLTKR
                     TIAVNLEGIEKGLKTGAVGGLNVPGRVLDVAVVANADKLKKRIADIVRASKDDDSEVK
                     TMADGKRMIVTVPSVRMDSGAEYTTGFTTVAAAVTEAIIDQFDVNMFEASMVKAAVWG
                     RYPQTINMLGSNLRSILDVPQLNEGTGYALRNIMANHIVMLTGRNAMNAAALSSIYET
                     AAAYEMGDAIGNFERQHLLSLAYQGLNANNLVYSWVKENGKTGTVGDVVASMVGRALE
                     DKVIKKGKKFPSGFVEYVTTDYPLWNAYVSAGMLAAICVNIGAARAAQGVPSTILYYN
                     DLVEHETSLPGVDYGRAMGTSVGMSFFSHSIYGGGGPGLFHGNHVVTRHAKGTVIPVI
                     AAGCALDAGTQYFSAENTSLVFKEVFGEIPEFKSPMKSVGKEAKKLKELV"
     gene            complement(16074..16715)
                     /locus_tag="PKM11_02485"
     CDS             complement(16074..16715)
                     /locus_tag="PKM11_02485"
                     /inference="COORDINATES: protein motif:HMM:NF033432.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfuA-related McrA-glycine thioamidation protein"
                     /protein_id="HNX47413.1"
                     /translation="MRPVVFLGPSLPLSEAGEILDADYRPPVRRGDLQHLEGVEIVGI
                     IDGVFLQSCSVGHREILSLLNRKVKMIGGGSMGALRAAEMGHYGMTGVGRIFKMYASG
                     EVQGDDEVALVFDPETMEPLSEPLVNLRSLLDAAWMAEVIDSVHRAKILDEMRSIYYP
                     RRTVPVFLEVAHRTLHGKDAEAFDRFFAENYRDIKKEDAITVLKLIKSVYEMR"
     gene            complement(16712..17905)
                     /locus_tag="PKM11_02490"
     CDS             complement(16712..17905)
                     /locus_tag="PKM11_02490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-related McrA-glycine thioamidation protein"
                     /protein_id="HNX47414.1"
                     /translation="MELHPVAKTYTKDGHRAISPEATLKRVEPLLPVAGITRVADITD
                     LDRIGIPVFSSIRPGAKEGAISIYNGKGASREQARVSAIMEAMERYSAEPKGEKVRRD
                     LMENMLASENAVDPRSLILPQMINVHVNFHPIAWVKGYDLIEGEDVWVPAGAVYHPYE
                     SNKDLQLFRSNTNGLASGNNLEEAILHAMCEVVERDAWSICEARRKPRGEIVVGDDCT
                     VVSDLLEKFSKQGVEVHLKDLTSDVGIPTIAAAADDVRMKDPALLNLGVGTHLSPRVA
                     AIRALTEVAQSRCTQIHGAREDTTKADLNRTLGYERMKRMNSMYFSPSDGIGISDFPE
                     FDTKDLLEDIEVVLDHLVEGGFEKVVVVELTRPELKVPVVRVIIPGMEIFAMDMDRLG
                     PRLVA"
     gene            complement(17948..18430)
                     /locus_tag="PKM11_02495"
     CDS             complement(17948..18430)
                     /locus_tag="PKM11_02495"
                     /inference="COORDINATES: protein motif:HMM:NF013224.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HNX47415.1"
                     /translation="MDLIDLEILRMLRKNSRENLGTIGDQLGVSKATVSRRISRLEED
                     GYVSAYTMQVNTGKLGLMRALIGLQVVGSPLGAVIDELKKFPGIQYAYKVFGDHSLIC
                     EVYASSVDSLYDLIQDKIVNIPNVQRVEVDILIERIPINEDAMFDLALPLAENEASRD
                     "
     gene            complement(18539..19213)
                     /locus_tag="PKM11_02500"
     CDS             complement(18539..19213)
                     /locus_tag="PKM11_02500"
                     /inference="COORDINATES: protein motif:HMM:NF014635.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HNX47416.1"
                     /translation="MDILELPTEPVAITLVKKGQPLPEGYQVPEKNIRHCQSVMRARR
                     GEKLLLTGDKHACHVGASALGLVPIPDKVRSGEFHYNLGMFDSVEAAKKMIDERPQLD
                     CGSVIATAVSPLSKAELPPDVIVVTGTPEQMYWLLPVAAKFFEGGKITVELEPFQASC
                     AYSTVYPYLHDTLSMSIGCYGCRKATDLEPTEMLVGIPATKLEAVVQALQKIKPVREK
                     GKIKSG"
     gene            complement(19309..20133)
                     /locus_tag="PKM11_02505"
     CDS             complement(19309..20133)
                     /locus_tag="PKM11_02505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47417.1"
                     /translation="MALCELFDLEELRLLENTLEDLGNDMFLAQMLSGSEQVRLLISN
                     DETPLAMAREDGGWKAVSFLWKEPSDELIELLPELDIKVYTCDTETYREAVYDHFARK
                     IMNEVEPALDDVPEDRTKKVSDLIWKEWNFKPGDLCYDCCCGSGVGSMALTKVGLRAF
                     AFDVDAPLLSRGLQIGRLQSWSTAQLDAAKVSQYLEKAPFALMLMAGDINVGNSWIWK
                     IIFEQVLLIGEQVMVTVGTQEEAEQLRSWAEAKGRSPRVFENERDPFYDRWVCSVR"
     gene            20230..21222
                     /locus_tag="PKM11_02510"
     CDS             20230..21222
                     /locus_tag="PKM11_02510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1616 domain-containing protein"
                     /protein_id="HNX47418.1"
                     /translation="MRAQPRRDWDLWSIGILSLVLILIIYALPDSALRIVIGLPFILF
                     FPGYSALSVLFPESKDLEIIERVALSFGLSIAISPLVGFGLNYTPFGIRLAPILFSLA
                     ALNVALSAGGLYRRDKAEAPYLPFDPAVVWKKYSTQFKAEKGVDKVLTIVLVISILSS
                     VIALVYVVAVPRQGESFTEFYILGPGGNATGYPRNLTVGQDASVIIGIANHEHRTVDY
                     TVELWLVNMSFVDNATQVHAMYFFDSFNITLEHTDVDLEGEWQAQWELPYEFNVTLGG
                     NYKLWFLLYKDGAPALPFAASPMLDYTDTSAEDRIIKAVENEVQSLNLNLRVTE"
     gene            complement(21223..21504)
                     /locus_tag="PKM11_02515"
     CDS             complement(21223..21504)
                     /locus_tag="PKM11_02515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47419.1"
                     /translation="MSGEDPKLNCVGCDTGLSFNEGEKLLVNGQLVELAGLDDIMEEV
                     RKLKLSQRKRVADELLLRAKERKAVPEGSEKQYRDALMDEYDRRYLTVM"
     gene            complement(21552..22277)
                     /locus_tag="PKM11_02520"
     CDS             complement(21552..22277)
                     /locus_tag="PKM11_02520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47420.1"
                     /translation="MGVSIAICEIDSDSALCKIGKTTLLKVNLKDVSGFEDLAEFDLV
                     VPVSQAKLLMGADWEAFLKRNRMDPEMETMYLEKVKNEADRQLLTAESQKMYTGWISL
                     DKVPADRLSALMAKAGKDDRLTGWDMLSFDDMAATCLKCPLSWDEGRGCMGTFGPENS
                     ALPGIAQKYNCAIVASVPSSVEGKKIFSVEDANKLLEEVKLLREKLPDEGKVMVRRYS
                     GVLDRLEKMGNVCLTYKTRFYFL"
     gene            22437..23204
                     /locus_tag="PKM11_02525"
     CDS             22437..23204
                     /locus_tag="PKM11_02525"
                     /inference="COORDINATES: protein motif:HMM:NF016124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47421.1"
                     /translation="MAETDTWPMASGDYVLGNEASSVAVLIVGRGAVEVPPELYRIKG
                     ILKTENIGLERVIANIISNPKIRVLVLCGKEEFGHFPGAAIHALMKSGVNEHRRILNT
                     RSAIPFLCDLPPDAIERFREQVELVDVMDDSPAQEIAAYDPIYEFSPESRERLESTLR
                     KLSKRKYSPFPEKAMFVRSKAFVGEGVSVAKQLHLASDDFITPMLRLPSDGLNTDMGM
                     VLLDEEFGVVLEPLQGRIITVPSVELALRLRSYLTGF"
     gene            23206..24090
                     /locus_tag="PKM11_02530"
     CDS             23206..24090
                     /locus_tag="PKM11_02530"
                     /inference="COORDINATES: protein motif:HMM:NF014105.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47422.1"
                     /translation="MYKFQTAQREFSIGGVKVGGQPGKRRAMLIGSLFYPRHSVVLDP
                     RKGALDKGKLNERLDCYLATIDNCGCPSGLMLYAESVDAARAYLEAVCDKVPGPLFAD
                     SGSAEVRLSFLRSAQEMGILDRVVYNTINAGLSDEEKEALRACPPVNAVVLAFNPRGD
                     DVKGRIYMLESGDDIIPQGLVTSAEELGIKNLLIDTAVTSPDLSAGSALRSILVAKAK
                     WGLPTGCALHNAVECLRLDGLEDPKEARRSVDASAVAISIMAGADYVVYGPLEYAKRT
                     MPVASFADKMMEQAARDL"
     gene            complement(24087..24914)
                     /locus_tag="PKM11_02535"
     CDS             complement(24087..24914)
                     /locus_tag="PKM11_02535"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47423.1"
                     /translation="MDDHAGTANPLLFISKAPGDFLAEHGLSLLIQTDQGKKVLFDTG
                     SSEKVFAHNLDLLGMSPKDIDAVFISHGHYDHLGGLPLLVKEGVPVHTHPLTFQGRRF
                     VETSGDRKEIGPSAELLPLLNEHPPIYDDRPKELVEGIGTSGEIFRRTDFERPASFLI
                     ERDGGTSQDIIREEQALCVSTRNGLVVLTGCGHPGIVNTLTQVSMHTGRRLIMAAGGF
                     HLGRADVELLLKTIEGVKRTGVNKVAPMHCTGFAATKLFSDRFPGFLSLGPGCSIEL"
     gene            complement(24933..26582)
                     /locus_tag="PKM11_02540"
     CDS             complement(24933..26582)
                     /locus_tag="PKM11_02540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylamine methyltransferase corrinoid protein
                     reductive activase"
                     /protein_id="HNX47424.1"
                     /translation="MALGVALDLGTSGYRGHLVDLDKKGKILATAITMRHPLPGANIM
                     DHLHFWMENGSEVGHRIVIETVDKLIETMGAKPEEIERVSVCGNPAQMSMFEKIEIRD
                     LAYAGQSILKRLNVKVPERKAHSIKAEELGMRSVRRTAEVRIPPSIRHEIGADALAMI
                     MKTGMMDKKETCMVTDYGTNAEMGLFYKGELYTGSAAAGPAMEGQSIDFGMLAAPQAI
                     SDVIPGEDGYWYNVVLNDKLHPVRSALVHPRTGDEKRLDGVVARGITGTGTVAAMAVG
                     LETGVIKLPYVDTPDRKIHLTNGIYFGEEDVREAGKATGAIRAGHRTLIEEVGVDDTD
                     IRTMYMAGASGTYVDPIKAQTVGLIPRVLDKTVQAGNTSLMMSYDILVDDDGLDNMQD
                     VANAISSKHIMFATSKVFEDIYVNEIAYWTEGMSMTMYNDMLKIAGLRPLPDIVRPKE
                     TIRLVLSDIPVIGARGLKTLDDVGVYLMGSFEGCIGCKKCQKECPECALQVSAMGHKK
                     FLIRVNTEHCLGTACKKCQSVCPESVYDFSALKIVKKGEDA"
     gene            26749..27414
                     /locus_tag="PKM11_02545"
     CDS             26749..27414
                     /locus_tag="PKM11_02545"
                     /inference="COORDINATES: protein motif:HMM:NF014542.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HNX47425.1"
                     /translation="MRIAQVTGFLGSGKTTFLIEVAKELNSRGLKVATIVNDVGHINV
                     DRKCMEVHGIDTMEISGGCICCEVQGTLTTTVTNIYMSFKPDVILVEPTGVAIPLGLK
                     QAAAQTVKKMPKILEQSPIVTFVDAMRIDKLMNNVRRLVETQIIEADAVLINKVDAVS
                     EERLRSVTELVKGLNPNVRLIYGSARTGQGIKEVADLMVNGEAVVYDLSDAEDRFDKK
                     YGE"
     gene            27419..27871
                     /locus_tag="PKM11_02550"
     CDS             27419..27871
                     /locus_tag="PKM11_02550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47426.1"
                     /translation="MDQKERQLLTHRASDELGKFSMWVRLYIKDPLDGKRSEEMVLDL
                     MNGITKECFARGADMIGHVKSFLTAEGGSTISVSLIDLDIPPTVQNRFDGTKMMRGEL
                     IVHVIVHGLWDPQVRETSLEFTKGFMAERSIDYEVINDFYEKEKRVKD"
     gene            27912..28964
                     /locus_tag="PKM11_02555"
     CDS             27912..28964
                     /locus_tag="PKM11_02555"
                     /inference="COORDINATES: protein motif:HMM:NF013381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HNX47427.1"
                     /translation="MLPRERFEAAFERAPVDRPPIMYQHLGAARTVLNAAGLTMREGF
                     HDPEKFAKICIMAQRITGFDNVMAGWGDILVEARAHGTKWRWPEKDYYPRSDGYAISS
                     LAELDKVQPVDPMKDEFWSVPLRAAGLMQERHGDEVAVVGCINGPMMMSGEVMGYENL
                     LMSTWSEPDLALQLMDRMLESSAMYGEHLGKMGIGHVFIEDGTCSPDVNSIEGLERFD
                     LGCLSKLMSSFRSNGLRSIVHNCAANPYLDGYTRMEIEALHLTPKTGDRRTIYDMFRQ
                     RTTVIGGIDQTFLLFKGTPEQVRKEVQAMISDWGDGPGFMIAPGCEMAFKTPIENIIA
                     LREGSVKNVKDIGNDG"
     gene            29148..30152
                     /locus_tag="PKM11_02560"
     CDS             29148..30152
                     /locus_tag="PKM11_02560"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MtaA/CmuA family methyltransferase"
                     /protein_id="HNX47428.1"
                     /translation="MTPRDRVLDALKGKKHDRPPVAVFTQSATMGQMDALGVSWPEAH
                     YNVDMMVKLGAGQAKVFGFEAVRAPFCLTVEAESLGLTADKGRKDRTPMLKGHPHQME
                     DEPALMDVGTFLKTGRAAICQQAITKMKAAYGAEYPVIAGNTGPFTLAGHLVSTENLV
                     LYIMVEPELVHKWVKAANVICKGYSQALANAGADVVQMSEPSASTDLLSPDMFNEYAG
                     AYIADSLAPVKGATGVLHICGNTTDILNNMINTGCKALSIEEKVVPEEAVKIVNHRAA
                     LIGNVGVVNPLLQGTPADVLAHGKRCAAAGFDVVSPGCGLSALISNDNLAALVKAVKG
                     "
     gene            30380..30781
                     /locus_tag="PKM11_02565"
     CDS             30380..30781
                     /locus_tag="PKM11_02565"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: protein motif:HMM:NF013607.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase ArsC"
                     /protein_id="HNX47429.1"
                     /translation="MLFICTHNSARSQMAEGLTNRYFSDTITAFSAGTNPGQVHPMAI
                     KVMAEKGIDISGNRSKHLNEFKEQDMDLVITVCDGANEICPFFPGAKDQEHAGFPDPA
                     AVEGPENERMDAFRRVRDEISDFILTRFAGI"
     gene            complement(30815..32779)
                     /locus_tag="PKM11_02570"
     CDS             complement(30815..32779)
                     /locus_tag="PKM11_02570"
                     /inference="COORDINATES: protein motif:HMM:NF017215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HNX47430.1"
                     /translation="MASRRLGLGLDTGGTYTDAAIVDMDTLEVLAKGKSQTTYHDLSI
                     GILGAIDEALNSDAYERGDIQFVGLSTTLATNSILTGKGGKVGHIGIGWTPMSDFRSG
                     ADMDAYIKGGHGVYAQQLAPLDTKALEEAIDAMRTEVDSFVVSGHFSVYNPAHEVDAS
                     RMIKQRTGLPVVLGHHLTSQLGVPERSVTAVLNARLLPIISEFLDGVERSLKERGVDA
                     TILVFKGDGTLMNIEKARERPVETILSGPAASLMGGKLLCKKDNFIVVDIGGTSTDIA
                     YLDDGFPRISKEGATVGHWRTRVRAIDIWTVGLGGDSHVVSDQRGNFKVGPERVVPLS
                     VAASSYPEIIGRMNDTSETNYYLHVERGTTKLSAKEKAIYEFVRAHPISTLEEIRLGN
                     SEIFTYRDVVKHLKDRGFLQMTGLTATDFMHVQGYFDRFDKEAARTGVQFMANWCHKS
                     FDDYVRSFHEEFITLVGEEIMRKVVLDESGDMSEGPGFNYLLRSMVNGNPGSSITNST
                     GLDRPLVGIGAPTHIYMPPLEERMNVEVIMPKDHEVGNAVGAVCSQISETVTAQVFPN
                     MDNLFFVLGPFGTPVTYGHVEQAVSAARRQAEEYVRNKVYEAGAENIRVRSDTYEKKF
                     YGGDNVEGEQTAWVDIVARATGDPVAKVKK"
     gene            complement(32833..34206)
                     /locus_tag="PKM11_02575"
     CDS             complement(32833..34206)
                     /locus_tag="PKM11_02575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47431.1"
                     /translation="MKGITSRTLQGIILGWAIAFEGFFALSLANSASIDGIGGVRAST
                     LQLAAIQLTALGIFISAMWAVKMTFPDLEKPILIKLLNFLTYLAMAMVVVEGIAIAVL
                     AGNVFITDFGGIGKKWIVLVGAQLFGIGIVSLRLWRIRNISSENWLTDSFGQIAAALI
                     AVEGLVAYGIAGTTRIIGVTGFQESTIANGGLLLMVVGLAILVLWTVPYDPWVVSKLP
                     KLRKLIDGWPSMVIMIVLGGAISAVCVVATYFVGPVAVDGVGSVSKIVVVAGVSQLFG
                     LGLISPLLWKIRKERLDRHYLSVLLVTMALALLAFEGVFAMALAANTYIEGLGGILEN
                     TFRLAGGQLLVLSVIGAMAWLVKDSPLLTRWPKRIVSSTFLLVTAFIAVEGLAVILMA
                     VNIRIDDFSGVGERYVLLGGLQIALLASIALLCWARTHGISARFKLAGTAAAAFVMLL
                     LPIALLL"
     gene            complement(34305..35069)
                     /locus_tag="PKM11_02580"
     CDS             complement(34305..35069)
                     /locus_tag="PKM11_02580"
                     /inference="COORDINATES: protein motif:HMM:NF013209.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HNX47432.1"
                     /translation="MPINESAVGKEIVQLKQKVDELGLELRYISTLLQSSQNHDAQGP
                     ELFDLLRGEVRKKAESRLDAGMAKRCDMRPDCRLRFMELLDENLALLERPRVTDEDLD
                     KQQKKLDSLRSHAVTGRCDGCFREVGSLFQDQTELMRQLRLYRSKEEIGHSIDEMPEG
                     EVVRDLLEPLSNPQRMLIMKSLSRSQRSFTELSSLTNLRGGNLLFHLQRLTGAGMVLQ
                     KGGRGDYALTLKGQRSLETVNDLYMRTSSADREDGS"
     gene            complement(35187..35822)
                     /locus_tag="PKM11_02585"
     CDS             complement(35187..35822)
                     /locus_tag="PKM11_02585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="corrinoid protein"
                     /protein_id="HNX47433.1"
                     /translation="MTNMDLLIDIVVKGRIKEAKGETQKLLDAGVSAKEIIFNGLSKA
                     MEIVGEKYEKKEYFLPQVLLSAQTLYQGLNLALPKLDTASADAAGRIVLCVVEGDVHD
                     IGKNIVKALLTGAGNTMFDLGRDVPLKDIVQKAKDEHAQIIATSTLMTPTLAGMKEIE
                     KMLAEGGMKGKVKTMVGGGATSADFAKSIGADGWGYDANEAVREAIRLLKN"
     gene            complement(36331..37269)
                     /locus_tag="PKM11_02590"
     CDS             complement(36331..37269)
                     /locus_tag="PKM11_02590"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HNX47434.1"
                     /translation="MRTIKDKRVLITGGAGFIGSNIAQALHEENEVVVLDDLTTGKKS
                     NLAGLDVELVTGSIRDADKVRGAMEGVDYVFHHAAIASVPRSVDDPVSSNQVNVCGTL
                     RVLMEARDAKVRKVVFASSSAVYGDAPSEIKHEDDLPAPISPYAVTKMTGEMYCRNFW
                     LNYRLPTCSLRYFNVYGPRQDPSSDYAAVIPRFISAAKAGKQLTVFGDGEQTRDFVYV
                     KDVVQANILAATDEKHHGEVFNVANQEKVTVNQLASLVLKVLGKKEEGGLVHLEERKG
                     DIKHSLADIGKARRLLGYAPRYGLEEGLSLTVTSML"
     gene            complement(37307..38038)
                     /locus_tag="PKM11_02595"
     CDS             complement(37307..38038)
                     /locus_tag="PKM11_02595"
                     /inference="COORDINATES: protein motif:HMM:TIGR00024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HNX47435.1"
                     /translation="MLHIDVTPDIRMFNGRCAMLLRSRTLVLGDLHLGIEASLELEGM
                     QLPRSQARETKRRIDELVKADPPKRIVLLGDVKHEFSRNLDQEWSQVRGMLEHLGSIA
                     DITVVRGNHDNYLATITSSMGLDLVDETVVDGIHLSHGHIAHPGRPMVQGHEHPSARL
                     FDGVGGYVKLPAFLYHQEAEVLVLPAFSPLASGNDVSALLAGDVLSPGLRGLDMGEAQ
                     VFGCSDIGLIRLGKVKDQAKRPRRA"
     gene            38134..38898
                     /locus_tag="PKM11_02600"
     CDS             38134..38898
                     /locus_tag="PKM11_02600"
                     /inference="COORDINATES: protein motif:HMM:NF024873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H-like domain-containing protein"
                     /protein_id="HNX47436.1"
                     /translation="MIRRTFLLLPGIGQLKERRLWESGVLSWEEFFERRHLTGISVQR
                     KECLDQELGTAKDLWDRGRTEYFTRLLPSGQHWRMYHRLKEDTAYLDIETNGLGPGAI
                     ITMVSVHRQGGTTTLTRGIDLSSENLTKALSGTKMLVTFNGASFDLPMIEREFPFAVP
                     KVPHYDLRHACPKVGLRGGLKQVELLVGLRRPQEVEYVTGEEAVYLWHLWERKGNENA
                     LKLLRRYNQEDTKNLEPLAEVVYGRLEESSLMGCGK"
     gene            38895..40565
                     /locus_tag="PKM11_02605"
     CDS             38895..40565
                     /locus_tag="PKM11_02605"
                     /inference="COORDINATES: protein motif:HMM:NF013528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HNX47437.1"
                     /translation="MTGDAEAFVERAKSLAARVRKARSVAIFSHIDADGVSSAAIAYR
                     AVERMGVNPKVHFLKSLSDKEIRFINSCDEELLWVCDLGAGSYNNLDQSRCIITDHHH
                     IFGSGQSFLEFFGGMQNMLNPVEFGFEGSSHLSGAGCTYFVARELDPVNVDLAYLAIV
                     GAVGDLQDKRARRLDGPLHSTVIEDALGTGVLQVMKDDLPFFGWVTRTAVAMIAFSND
                     LKAIGCECTFSEVGQMFKGQGVRTYRPQRDESIKDENLSKYYSWSELDSEPRGKIKIA
                     LMDSLQRMGKDPSVFEGMLGDVYLFPRFPVGSASREAKEFATMLNASGRYLHSKSDAA
                     PSETVVDQQAVTEVEERSGGFQGELIIKACLDPVSFSSDAMAKLGNHRDNLRKGLEEI
                     HSIVVMDHIQYIKGRIDTPENKNKSKYTLTVEDTILGIIVGMALEQRPNSNRSNLSVR
                     DDMPLIALAEASPDSDTSEPIATDGNMGAPGERVKVSGRMKRDLIDKGVHLGEAMKQA
                     ALKVKGAGGGHNVAAGATIPKRKIKAFLQALDEEVGGQMARFTPSERP"
     gene            complement(40543..41454)
                     /gene="argF"
                     /locus_tag="PKM11_02610"
     CDS             complement(40543..41454)
                     /gene="argF"
                     /locus_tag="PKM11_02610"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HNX47438.1"
                     /translation="MKRDLTTMLDVQVDILDILDAAEDMKKRRDMDFQPLKGKVLAMI
                     FEKSSTRTRVSFEVGMIELGGFAVTLNTKDLQMGRGETVADTARVLSRYVDGIMYRAY
                     EHEMVMELAKHATVPVINGLDNFEHPCQIMADLLTVKEHLGKLKGIKMAYVGDGNNVC
                     NSLMLGCAMVGMDLSCGCPKGYEPDPGVVKKAKAIAKKNGCQLNIVESPKEAAKGADV
                     VYTDVWVSMGQEEEQKLREKIFKPYQVNADLMSVAHKNAIVMHCLPAHRGMEITDEVI
                     DSTASVVLDQAENRLHVQKAIMVALMG"
     gene            complement(41617..42417)
                     /locus_tag="PKM11_02615"
     CDS             complement(41617..42417)
                     /locus_tag="PKM11_02615"
                     /inference="COORDINATES: protein motif:HMM:NF014566.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HNX47439.1"
                     /translation="MREKAGLLLPILIIAVAEALYFTGSVESCLALHALNIFACILLP
                     IWDDKRMLMYQSFALVSLLRVLNIGMPVFFTETLLWMPFVYGPIIIAGYIVWRQTVMG
                     VEKMHWRNLVQFLNGHGLRSNVTWKWEYLLIAIIFGYLCSNLEFFLLDNQALVYDLGP
                     LTLSKLLLVMVVFVGFGEELIFRGLLQSSIEKHYGKYLAVFVSALMFAIMHSGYRSIP
                     YLIFVFLVGLTLAYAYQRTSSLGLVALMHGLLNFFLFSFLPFGYGILP"
     gene            42696..43268
                     /locus_tag="PKM11_02620"
     CDS             42696..43268
                     /locus_tag="PKM11_02620"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HNX47440.1"
                     /translation="MTEIGVEQIKVLSDPNRLAILSLLAIREMTTTAISDLLGLSVQN
                     AQYHIKKLLEAGLIVPTRTELVGNLVEKYYRSAFEPGIMGDAAGVSSVDIAERLNIVF
                     AALGAIKGILNRGIRTMDERKDYFMNVDERPNYPFGANYVVLPVSDSAAQEAEKLISD
                     LDDRLKELSDKHPEEGKPKFAILYSVFPFE"
     gene            43317..43390
                     /locus_tag="PKM11_02625"
     tRNA            43317..43390
                     /locus_tag="PKM11_02625"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43352..43354,aa:His,seq:gtg)
     gene            complement(43397..44566)
                     /locus_tag="PKM11_02630"
     CDS             complement(43397..44566)
                     /locus_tag="PKM11_02630"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX47441.1"
                     /translation="MVELSPLAPVFLLLATSEVVLGSYVLLKGRSSPVNRSFFLLTIL
                     AGAGSVLDLLVSSVGTGEQAIWAFRLLVFLLIVEMGVAYRLSTLIPHPVPKLLFGKNR
                     WAYEISVLTVALATAFSVGRMVDDKYGWVPVNHLPFQLLLLLLLVYLTLLLVTVVRRW
                     GALRGVQKRQAILFNGALAIPAAGMIVIMGLAVFDAEVPRIYGFGELISVAVVAYGIL
                     RYQLLVPPRVVEPTVLHRPVPSLVKGRAYLFEFASSDRMFESMVQEMSGGMSAFIITR
                     THPDQLRARYQLMHTPILWLAQTPGPDRVDPSNLQLLTHMTLEFLRNGPSLIAMEGLE
                     YLMLNNDLNKVLRFLAQLRDEVIVEGSILVITVDPRTLTERQRAILERELEVVKE"
     gene            44693..>46139
                     /locus_tag="PKM11_02635"
     CDS             44693..>46139
                     /locus_tag="PKM11_02635"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018035149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008452 - RNA ligase activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HNX47442.1"
                     /translation="MSWNGPLEKIDDYRWKIPRSYKECMNGDAVIFADEKMIKTIISD
                     NSPEQAANVACLPGLVGRSMAMPDIHWGYGFPIGGVAAMDAEEGVISPGGIGFDINCG
                     VRLITTNLGVKDVTPKIKQLINTLFQNVPAGVGSKGVVDVAANQIDRILEEGAEWAVA
                     EGYGWSEDLVRTEENGRMKNADASKVSAKAKQRGVPQVGSLGSGNHFLEIDKVDKIFD
                     PVAAKVFGLEEGQITVSIHCGSRGCGHQIATDYLQVMERSVKDRNIRLPDRQLACAPV
                     NSKEGQDYHAAMACGANYAWANRQMIMHWVRQSFEKVFARPAEDMDMSLVYDVAHNIA
                     KVEDHTYEGKRRKVYVHRKGATRAFPAEHPDVPSIYRSVGQPVLIPGDMGVGSYVLVG
                     TERAMQESFGSTCHGAGRIMSREAAIRSYSVQAITQEMETKGIYLKGSTRDGIQEEAP
                     GAYKDIDDVIRVVVGAGLSRPVAKLTPIGVMK"
BASE COUNT         9480 a        13471 c        13164 g         9924 t
ORIGIN      
        1 atcccgtgct ccgtggccac gatggtcatg acgttgtcgt tgaagtactc gttcctcagc
       61 ttgagcccct cgggaagtag gcgccacatg gcgtccagca attgcgaccg gacctcctcc
      121 tcggggtcca gcttcatgtc cgacaggtct tctttgggaa cgccttccac gaatatttcc
      181 aatcgcgtta attgctgcac gcgctccctg ccgtacaaac gccagaggct ggccagcaac
      241 cggggggcgt acgactcgtc ctttatggtg acgaaggtcc cgccttcctg cgattccata
      301 tccgctatgt cgtagaccgg cctcttgctg ccggactgct tgacgcgcat ggatatgatg
      361 aagagggtct ggtccggccg gatgaggaga cgtacccgct cgaccatggt gctgatcccc
      421 atttccatga gtatgcgctc cagcatccac tggtacgact ccagggcgta ttgctcggtc
      481 ccctccagct cgaattccac caagctctca ccccagcagg ccggagacca gcagcgcccc
      541 gccgaccgct ccgatgtact gagagtcctt gggcactatg ggccgatggc cgagggtgtg
      601 ctccatggcc gtgaccagcc cggatatgag ggacgtgccg ccgacctgga tgatgggctg
      661 gcgcacctct atctcctgca gctgctgctc gtatatctgc tcggccacgc tgtgacatgc
      721 ggcggacgcc acgtcggcca gggtgttccc ggcggccagt gacgtgacca ggtcctgtat
      781 tccgaagacg gagcagtagg agttcatctt gaccttgccg tgatcgccct ggtccgccaa
      841 ttcgcccagt tccgtgatct ccaccttcag gcgcttggcg gtcatctcca ggaacctgcc
      901 ggacgccccg gcgcagatac cgcccatggt gaagttgtcc ggtatcccgt cgcgcacggt
      961 gatggccttg ttgtccatgc cgccgatgtc gatgatggtg gcctcgccct tctgcttgcc
     1021 ggcgagccac acggcgccct tggagttgac cgtcagctct tcctgcacca gcttggcgtt
     1081 gaacttcttg cctagcgtga atcggccgta gccggtggtg cctatgccct ccagctgctc
     1141 gaacttgacc cccgcttccg ccagggcgtt ggtgagcgcg gtctcggcgg acgaatagac
     1201 gtcggtcgtg ggcaaccagt acttgccgat gatctggttg tcgcgcatga tgaccgcctt
     1261 ggtggtcgag gaacccgaat ccaatccggc cgttagaccg acctgcctct ccctggccag
     1321 cagctccttg cgttccacga tggtcaccag cgcctccatc ctcgtcagta attgggcggc
     1381 cttggtcctc tccgtgaagg agtaggtgac cactggcagc cgcacgtgct cctgcacgaa
     1441 cttcctgagc tccgtgcgca ccaacgcgcc ttcggcgcag cggaagcagg tggcgatgaa
     1501 tatcgcgtca gcatcgtagt tcttgtcggc cagctcgatg gcgcgggcga tcatgagctt
     1561 cagctggggg ctgttggggt tgaacccgaa ctcatcgacc gccttatcga tcttgttcat
     1621 gtccacgtcg gggtagacca tcttggcccc cacggtctcc gcggcatgtt ctatctccgc
     1681 ctgcacggcg ctgtattccg tcccgcagga aagctgggct atctttatca tttcaaaccc
     1741 tccaggaact ccttcacccg tacgaccatg tccttggcat catcctcgtt ggccgggtaa
     1801 tcgagggata gtatcggcac cttccgcttg cggaccagca gtttcgccag ctcgttcgtc
     1861 ctctggcacc ccacgcaccc gaagctgtag ggggcgtcct ccatgaatat ggcagcctcc
     1921 gcctggtcga tgagcggacc gtagatggcc aatcttccgc ggatccccga agggatctcg
     1981 ataccggcgt acttcagccc ggtcttgacg tcgtccaggg tgacgttcag cggcggcgcc
     2041 tcgatctcgt tggatgtgac gcggtcgcgg agggccttca tcaggctgag cggttcgtgg
     2101 ccgaacctct ccaccagatc gaaaaggatc aggctgttcg ggggcattat gaatatcttc
     2161 atggggacac ctcgtcgatg agcttcctaa ggtcgttgac cgggatcttc tggcgtttct
     2221 tgggagtggg cggtttctcg cccttctcca cgcatatcag gccctgctcc accaggcaca
     2281 ggtccttcca ttccttctcc agctgggcga acccgggccg ggaaccgtga tgcgcgcggc
     2341 agcggcgaag gtcccccatg gggaaggcgc ggatcttgga atagatgcgg ttggggtcca
     2401 tcttgcggac ctcgtccagg gtgcgcttga cagcgtcctt ggggccttgc agcaccaccc
     2461 cgtaacaggt ctccttgacc gagatctcgt tgcccaggtt gtgaatgaag cgggcgatgc
     2521 ggtccggggt gaggtcggaa gtgggcgcta tgaatatcaa cctggtctct atgttgctgt
     2581 ccatctcagt cctccttggg cttggacctc ttggcgctgc tcttggcctt cttggcggcc
     2641 ggcgccttgg ccttggccgg tttcttctgc tcttcggacc cgctcttggc cttggtcggc
     2701 cttttggcct tcttcaggac ggactcttcc ggggtcgcgc ggcggacgta gatgatgtcg
     2761 ccttcggata tgccggacat catgtcgtcc aggtcgccga tgaagcggcc cagtatgctg
     2821 gttccgggag tttcctctcc ggtgggaccg aactcctcgc tctcctccag acggatgcct
     2881 atgagcccgc gctgcggccg ggacatgttg gttatcccaa tgtcgccgcg caccgagcgc
     2941 ccttcgaacg ttttctcggg atacaggtcg gcggccagtt tgggatcccc ttcgaaagtt
     3001 atcatgggca tgccttcgaa ggtgaagtgc accttcatgg tgcctatggg cttgtggtcc
     3061 atcccggtga ccttgcggaa gtagcgcacc gtccaggggg acctgtcggg gtccatggtg
     3121 atcgggaaca ccttctcctt ggggacgccc atggtctcga tctccttctc cttggaggcg
     3181 tagatggtca tctccggctc ctgctcgact atcatggcgt cgtcggaggc atcgccagtg
     3241 cgcttctgga ccttgcctat ggattccagg aacctctgcg cctcggcctg ggtcttgccg
     3301 atggtcatta tcctcagggg gtccggctgt accaggaccc tgcccttcaa cggaacgaga
     3361 tgcaccaggt tgtggccgtt ggtgacctga cccacgatgt tgtgggagcg gttcagctgg
     3421 cggacctggt tgtagaagaa tatcttgccc acctggtagc ccttgtgcct cacggtcacg
     3481 gtgtccggat ggcgcacgtt ggtgtactcc tgtcccaacg aggtgtccat gttggcttcg
     3541 ctcgccgtgt agctgaagcc cttctcgtcg atgggcaggc tgccttcgct ggtgaccacc
     3601 aggaagtgct cgcagcacaa cggtgacctg tcgtccagct tcacgccgac gaaggtctcg
     3661 atgagcatgc catcctcgac gggaacgtcg aggtcggtga cggagaacgc gtcctgagag
     3721 gtcatgcgca gcaccaccgg ctctatgtgc tcgatgatgt cgccctcgtc cagcatatcc
     3781 aggatatgcc tccccctggt gaccctgccg aacacggcgt ccttcaggcc gaggtcgtcg
     3841 ctcatgtcca ccctggcgat catgaagtat gtggtgttga cgtcgtaccc gcccagggcg
     3901 aacaagcagt catagcgttt gtaagaagag gtcccgcgtg acttctccag ttcggtcggg
     3961 aaagcgccaa aggcgtgcag ccggctggtc tgccagcgga ggttcttgcc caccacgtca
     4021 tggtaaagac gcttccacgc ctcggcgaac ttgctgccgt tgagctcgat gatgaagcag
     4081 ccccgggggg ttttcaccat gtactcgttg gtcagctttc gctgggcgtc catagggcgg
     4141 atcagggcca ccgagctacc cgccacgtaa ggctctccaa caatggcctg ggccaccgtt
     4201 gccccttcag gcagctcttt ttccttaccg ttcacgacag ctctcatctt gtccccctca
     4261 tggatgcagt acgccaatta taaggttatt cctgatccgt tcaatctggc tagggatatg
     4321 cggtgcgtga tcgatagcca tgtcgggtag atcggaaact cggtgcaagt tatgaatagc
     4381 cgtaagacgc tgaacaccaa cgtggatagg gatgccatac gctcggcggt acgggaaagg
     4441 atgctggcac tggttggcat agaggcggtg gagtacctcg accagaactt tcgccaggag
     4501 atagaggagc gggaacgggc cgctgaggcg aacggtgcgg tgggcggact gatggccttt
     4561 gtgaacactg gcgtgtggga ggtcctttcc aggcaggagg tcctggtgat cgtcgctcag
     4621 cctaaggtcg cgatccttag tccgcaggac cacctggttc atatagtgga ccagaagggg
     4681 caagtgatcg gcgaatatct gccggaaggg aggcgcgacg aggtggagct ccgagagaac
     4741 gcctatctgc tcagcgagga cttcgttctc tacggggacg tggacatggc cggtgagcct
     4801 tactttctga taccccccat gccctttcct cccttggctg atatggacgg cataaaaaaa
     4861 ctggtcagcg ccagcatctc gacgatatcg gacgatcata tacgtgagcg tctgggttac
     4921 tatgatacca agtgttggac gcatttgata ggatacgaca tctaaggcat ggtcttcttg
     4981 accttggcca cgatctcatc caacttgacc tggctgacgg tggtgccgcg caccacgccg
     5041 gtgacgatct ccattatggt gcccttggtc ccgatgtcct cttccttggg catgaccaaa
     5101 cgtgtcttgc aaccgatgcg ggcgaagtcc tcgaagtcca ccggggcctg acagcagatg
     5161 accgccggca ggtccacgtt cctcaggatc aatcgcgctt tgtaaatgat gtggttgcgt
     5221 acgttgccca ggtgaatgag cgccaccttg aactgctgga tgcgggccac ctctatgggg
     5281 tccagaccga acagggaact ggtggagacg tccaccgcat cgctgggaac gccggaaccg
     5341 gcggtgatga ctatgacgga ggtatcgatg ccttcctccc taagcccgta agtgatctcg
     5401 cagaccggct tggtgatgtg gcgcttacca gggcccatgg ccactgccac cacgtctcga
     5461 ccgctgtcgg agatggtggc tctctgggcc agacttcctc ccacacccat tcccctggcc
     5521 tcgcggcact ccacgaaacg ggtcttgcgg ccgatggaat ccttcaagtt cagaccccac
     5581 agacatcgga ctcgtcgcca tccaggtctt cctgtgagaa gcccttcagg acctcttgag
     5641 gagttcctat cattatcatc tttccgccct tcatgagacc cacacgatcg caacaggcca
     5701 gaatgaagtc catgtcgtgg ctgacgatca ggaaagtttc gctcagctcc ttacgggcgt
     5761 gcagaaccga tttggcgacg gcctgacggg tgatggggtc catggtgccg gtcggctcgt
     5821 cgagaactac gaagcgcggc tcgattatca gggttcttgc cagggctatg cgctgcttct
     5881 cccccacgct cagagcgtcc gggtaggcgt agagtatacg ctccacctcc ttggcggtga
     5941 acccgacacc acgcatgacc tggatggcct tcatcttggc cagctcctga gggagcttca
     6001 ttcccaggca gatggtcagg ttctgcaata cggtgttgaa cgggtaaagg gcattctcct
     6061 ggtgcatgat gcctatgtac tgggtggccc gtccccggcc ctcctcgccc atgtccgaca
     6121 tgttgaccca atcgtcaccg atgcgcacct ccacatcgcc atgggtggcc ggggtgatcc
     6181 cggatatcat gcgggagagc gtggtcttcc cggccccgct aagtccgatg agaccgaata
     6241 tctccttttc gttaacctcg aaggagacat cgtcgaccgc cctgacgacc ccgcggacga
     6301 tggagtagaa gtacttcttg gcgccgtcca cgcgtatgac cggctgaccg acctggacgt
     6361 ccatcttctt atcccttacg accttgacgt cgaactcctt cgcgatatcg catggagcgc
     6421 cctcggcctt gatctttccg tcctccaacc atatggcccg gtgagacagc agctctatgg
     6481 ccttgggcca gtgagaggtg accaccatgg tcattccggt ttcctccacc gccttgatga
     6541 gggctttatg aacggtatcc gccgtttccg ggtccagggt gccggtcggc tcgtcggcga
     6601 ggaacagcaa aggttctctg gccaactgtc tggctagaac cgtcctttgc ttctcgccac
     6661 ctgagaggtc gcgagcgatg tgcatggtac ggtaggtcat gttgaccatc tccagcaact
     6721 tgatggcccg ggccaccttc ttatcgtctg acttctcctt catggcctcg aagacgttct
     6781 cgatgacgct gagatcgccg taaagagcga acgtcctctg cagcatgatg gcgatacggg
     6841 ctcgcatcgc tacgcgcaac ggatcccttt ccttcaaacc ccagaaatcg atctccacga
     6901 tcttggtacc cttcccgcac tgcgagcact tggcgccagg cgaaggcatg tcaacccagc
     6961 cgcatgattc acaatgattg acgcgataga tgatgcggcc ggagtctggc ttgtactctt
     7021 cgttgccgcg catggcgtga atcaggacgg actttccgct accgctcttg cctatgagcc
     7081 cgaggacctc gccggttctt acggtggtgc ttatgtcctt gagcacctgg tttccattga
     7141 agctcttgga gaccttgtcc aaaattatga agacctctga accctgggcc ataccttttg
     7201 ccaacgatta tggcagatat aatacttacc ccgtttagaa tgcctggcat taacgattgg
     7261 atgatgtaag atatttatgg atggattata tatccatccc ataatgccaa tgtccttcag
     7321 ttcctacttt gccggagggc caacacccaa gttcaacgct tatcatatct ggaaggcgca
     7381 ccaggtggtg gccaaagaag gccccatcgg acgaaaggcc ttggccgagc ttttacagat
     7441 cggagagggc agcacccgga ccatactgga caagatgatg cgggagggct ctatcgagag
     7501 ctctcggctg ggaataacca tcacagagcg aggaaagcgc aagctggaca cctccggggt
     7561 ggaggtaagg cagatcgacc tttccgacct aactttgggt aagtacaact gcgcagtgct
     7621 gatcaaagga tcagcggaac gtgtgcatct tggctgcgaa cagagggacg aagcggtcag
     7681 ggccggagcg gtcggggcga ccaccttggt ggtaagcaat tcacgcatag ttttcccagg
     7741 cgatgaggag ttcccggacc aatcgttggt cgcgcccttg aagaactatt tccgcatgga
     7801 cgacggggac gtgataataa tcggctcggc cttcaattac gaggcggcgg agaagggagc
     7861 ggtcacggcc gccctttcat tgagcaacat atctcgccga tgctggaacg aaggcaccag
     7921 catactcagt caggacaccg aggcggacga ccttaggtgc ttggccctgg ccattcacga
     7981 gctactagga cggttgccgg tcaccatgcg cagcaagaac catcctggcg tgcgctgcga
     8041 ggagggcgag atcatcgaca cccgcttcac cggtcccatg ctggaggaat ccatgaagaa
     8101 gggcatgatc atacgacgga cctccatcag tggaccctac cgcggaatgc cggtcatcgc
     8161 cgtaccaatt atgcgcaaga aggaggccat agcctgcatc gccaccatgg accttggtaa
     8221 aggaacaccc tcggaactgc tgaccaggtt ggccgagcgg tcctagaagt agtaccagat
     8281 gctccggtac tggcttgggt cctcgcctct ttcaaccaag gccgtaagga aatcggcgat
     8341 tggcacgtcc tgatgaacgt acatcgaagc tacggcgatg ttcttttccc agggatggaa
     8401 ctcgtatact cgttcaccgc gaggggtcag cgatatcagg tcatgatgct gccaagctct
     8461 cagatgattc tttcctagag cagggatgtt gaagaccggt tcgtcggtcc tgctcaatcc
     8521 ggggatcatt ctggcttcct ccttgtgttc ttgcagcagc cgggcgatcg gcacccggta
     8581 ctcggacgtc tcctccttgc ctttggcgtt gaaagtgtag tatgggtcga cccctatctc
     8641 cttgagcaca gtacgcagag ccaccgtttc aaagcgccgg cagttctcca tggtgaagac
     8701 ctgctggttg tagacggata tgccaaggga gcgcagggac cgaacggcgt tcgcggcctc
     8761 cggtgtcact tcataggaat gttcaaaatg cgtgaccaag gcgaactccc tgcccggggg
     8821 gtcatgcata tctgagatcg tgtccaggaa accggcgtcc atcctcatgg ggaggaccac
     8881 ggggaccctg gtgcctagac gtagcctctt gatgtgcggg atgtccgcca acctaccgag
     8941 aagggagcgg aggtatgtat tggacagcat ggccgggtca ccgccggtga tgagcacttc
     9001 gctcaccaag ggatgatccg cgaaccattc cagggccgcc tcgatcttct ccgggggggc
     9061 catggcgtcc tcggaaagaa ccccttcgat ctcccagttc ctctggcaat atacgcagat
     9121 ctgggcgcag gtgttgtagg gcttgaatat ggctatcatg ggatagcgcc tggtgaccag
     9181 gtccaccggg gaggtctgac cttccatcat gaagtccaag tttgccgatg gatcgttcct
     9241 ggaccggaga atcgcctgca catagctgag cgggggtatc acctgggccc gcacggcgtg
     9301 gtcccatttg cgcgagggtt cccgatccat caaaggaaga tagtaaggag tgatcccgaa
     9361 agggatccgg ttcgtaacgc aaagcgatat cgcttcgcgt tcatcgtcgg tcagctcgat
     9421 caggtcccca atgacctccg gcgagagcat gatgttcttc gtgtgccaaa cgtagtcgcc
     9481 ccagtcatcc gaagtagcac cgagataatc caggatccta ttgcgattct ccacccgctt
     9541 tttgatcacc aggggctcga gaccgctcgg atattcatcc gtccattcct tcactgcccc
     9601 ggccatcccg tccaggtaat cagagcgcaa acgaccgccc tccttcccgc ccagggtgga
     9661 gaagtccggg gcctcctgaa gttccagcac cggttgcccg gtggtgcctt tcatgatatg
     9721 catgatatcg ctgacgaaag cctgacgtac gtcattaacg gaaccatggg ataagttgaa
     9781 cagattttcc atcactgaaa cgccgctcac cctctcgttc ctcggcgaaa ggaagttacg
     9841 catcacccgt atggagtgca aggagttcga tcgctccagg gcgtgaagat gacagttgcg
     9901 ggaatgcagt tcggtctccc tttccttcaa cagatcgaac attgcggagc gggccgatcg
     9961 aacgtcgtcg gccgaactca atgcttcatg catctgggga tcgctcgccc ataacagggc
    10021 ctgtccgatg tccttcatct tcctcccggt ttccgaggaa cctctagctg gggtctttgt
    10081 gttgcgcatg atattacctg ggccgcccta aacgaatcga aaaagaagat cgtcccgcag
    10141 cgcgaccctc tatactagat gctcatctta cttatcgttt cccccctgac gagggaatat
    10201 gattatctgg ctcgatgaca ttgtagatgg aatgtccgat gaaacggaac ttacacttca
    10261 ggccacggtc aaggtcgatc caggcgtttg ccgattaccc agcaccatcc aggcccgcac
    10321 cgatgggatg atcgtggagt tcgagatact gcatagtgat tgcccgcatg tgcgcaacct
    10381 caagaagatg ctgaaacaga tggagatctg ggatatcatg aagatgccct acgccgagaa
    10441 caccatctac cagatatgcg gtgaagcgct caagcactca tcctgcccgg tgcccatggc
    10501 catgataaag tgcgccgagg ccgccgcgga actggcgctc aagaagacgg tgaccgtgga
    10561 gttcgtcccc tgatcattcc gagagaagct ggtcaatgga gggcatgccc accgcggcgc
    10621 tcggtcctgc cagatacatg gccacgaaca gcgattcgcg aatctcgtcc ttggtggccc
    10681 cggcctccat ggccttcttg gaatggagcc tgaaacattc atcgcatttc agcaccgcgg
    10741 tgaccgccac ggcgatgagc tccttctcct tgaagctcag cttgttgtcc ttgaacacct
    10801 cgttcttgaa acggtacatg gctcgaatga cctcgggctg ctgctcggcc atctgttcca
    10861 ggctcatgta tcccgaatca cgatgcggag atattaacga ttggtgggaa acaacctttt
    10921 tctaacacga tagcgtttag ggccgcgtgc aaccagagga gagagcggtc gagatcatca
    10981 aaggaatgac cggcacccag aaggccttcc ttcttccccg tgatgtgatc accgcggtcc
    11041 agaagataga ggacagcatc aagtcccaga tcgggctgga cgtggtgaac gaaggggtca
    11101 accagtgtct gaggagacag catgtcattt gtgtcatcaa ggacacccgt ttccgacctc
    11161 cgccggagcc gaccgtgctc atgatgggcg actcggacct ggtgatcggg accgaggtcc
    11221 ttccgggaca gcactccctc ttcaaggacc gggataatac ctgttggctc ggtgatgatt
    11281 tcgtggtgtt caccgacaag gttcccaaga ccaaggagtt cttcctcatg ccacccgtct
    11341 cattcccgga gctggagcag gtggccggag ccgtcaacat cgtctcctgc agcccttcgc
    11401 ccttgggaga cctggtcata aagaactatt acgagctaga ggacaatccc aagctggcca
    11461 gcatcctggt cggctttgac ctgtcctgat ctttttatat cacggccgtc aagggacgtc
    11521 cgtccacaca tttttttaaa aaaagaagat aatgggaaag ggtttgttct ggcgagctca
    11581 accgcccccg ctgggagtga gggtggagat gtcggcctcg acgtcttccg tcaagccctg
    11641 gaactccccc agcactaccc gggtccgctc cttgtaggag gtccgcttgt actcgctcgc
    11701 cgacgcgggg tccaggttac tggatacgta ccagaggttg taggtgtcga gcagagccca
    11761 ttccacccca ttgcggtcta gcacttccag tacctttccc accgtcccgg tgaccctgta
    11821 cttcgcgtaa tctcctactt gcattggaca ccttacttag cggggatgat ggcggtcctc
    11881 tcacccatag gcacgaactc cctcaggcag ccgcgaccga actccttggt tatgtttgcc
    11941 cagtcgaagg gcaggttctt gtcggcgaat gcgatcttta cgagggggtt gcacacatag
    12001 gcgtctccgc gagcggcgtg gggagccatg gcgataccgg tgtatccgct caggtgaccc
    12061 acgttcatgg cgtagttcgg gaagttcgga ccgcgcagct cgtgcggcag accctcgtcg
    12121 ctcctgtagg agaacgagtt ggacgcaccg cagttgtcct gcaggtcgta tccgtagaac
    12181 ccgagccttc cgagcctctc acggtgctgg tacatagaga ggtaccatcc gttgacaccc
    12241 gcgttggcgt taccagtggc gaaggcgata ccgataccgg tagcggctgc ggccacggtg
    12301 gccctctggg acccaccgaa gtgggcttcc atggcggccg ggtagcgctc gtacatctcc
    12361 agggcatagg agttgatctc ggtaccgagc ttctcgatga gctcggagct gggcttgctc
    12421 ttgcaatacc caccgtactt gtccttgatg tggtccactg cccaataggt gtagtcctcg
    12481 aggatgttgt cggtgtaggc ggcggtggca tactgagtga acccgacacc gccggacatg
    12541 tatgatccga ggtatatctg gtccaatacc actgcgccca aggcgacagc ttccagggag
    12601 gccctggcgg ggtcgtccgg cttggtcctg gtgctctgga ccatatcggc cagcacaccg
    12661 aacggaattc caccgggctc gttggggctc ctggccctcc tggcgggcat catggtaccc
    12721 atttccacca ctgcggcgtg cttggcggcg aaggcgaagt cggcgattgc ggcttcaccg
    12781 gcagccagcc ggtacgcggt gatgaaggcc atggagatct gcatcgcaga gtgcctggag
    12841 atcgtaccac catcgcacac acgtccaatg atggacggaa cgcgcacgac ctgccacagc
    12901 ttcttgccga cagcggcctt cagctgcttg gcctggtcag cggggaactc cttgttgatg
    12961 tcgatgacga agcacttgtc gatctcgtcg atcaactcgt cgtcgccaga gaacaccttg
    13021 acgtaggagt ccttaaccag ctcggggcaa agctcggcca tgtgctcctg aaccactgcg
    13081 ccgcctggca tggtgtggtt gacagcttcc aggtagcggt taatggtctc gggggtgacc
    13141 tccttcgaca gcctcttctc tataacgttg tgggcgacat ccagaccgac gataacggtc
    13201 ctgcgtatgt catcccagca ctgctgcata gcagcgttgt tgacccagtg caggtcatcg
    13261 gcctcgccat agatgtccgt gtgggacaac tggtagggca tcaagacacg ctggcctaga
    13321 gccacaccaa catcctggtt catcatgggg attccacggg ccttggcaat cttgttagac
    13381 tgctcaaccc actcccgctt cctcttcgac tgtctccagc ctccgtagga atagtgcttg
    13441 gagcggacct ccgtggggtc ctccttgaac ttcttgtgca tggcggcgat gaacannnnn
    13501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnatcaa aggtctcgcc atcgatgagt
    13621 tccttggcca ccttttcgac gtccctctcc ctcatctcga tgatctgcct tccggacagg
    13681 gtaccagtgt cgattcccct gaatctccac atgtacatct gcgccctcac atacggtatg
    13741 atgggggccc agtatacgga gtcagtgaac tgaacgtacc tgatcctgtc tcccttcttc
    13801 gcaccctcta tgggctcgac caatgccctg atcgggcaat cgggctcgct accctcagcc
    13861 agcggcgggt ggatggttgc gtagtcggaa ccggggaccc tgtgtcccaa gatcttgacc
    13921 acgtcgtcca tcggaacgtc gcgcagcttc tccagcttga cgctggggtc catgaaccgt
    13981 ctgcggttct tggcgggcag ggtgttgcca ggatagaatt gtgccttgta ctttgtctta
    14041 gccatgttat ttcaccaatc ctttcttaaa gtctgaagta gtgggcttga acttgttgta
    14101 gcgacctacc tccagcgtga agctgaaggg tagcacttcc ttgcatacct cctcaacgtc
    14161 cttcagagcc tgcgggacaa agtcgatgtc gcttatctcg acgaaaatgc gaccgacctg
    14221 gaccgtaagc tccacgtcct cccctctgac cttgatcttc ttccgttccg ggtggttaac
    14281 cggaccacca gtgccgggac cggccttcat tactgttggc aggccttcgc cctggatgtt
    14341 tatctgcctg acgttcttca cggtgtacag cttgttcagc agcacttccg tggtggacgc
    14401 ggacagtagt ctctccggga agatctgtat ctcgggtagg gggactcctt cagaggcagg
    14461 cgtactcatg ttcagaccag ctccttcagc ttcttggcct ccttgcctac cgatttcatt
    14521 gggctcttga actccgggat ttcgccgaac acttccttga acaccaagga ggtgttctca
    14581 gcgctgaagt actgggtacc agcatccaga gcgcatccgg cggcgatgac ggggattaca
    14641 gtgcccttcg catgcctagt aaccacgtgg tttccgtgga acagtcccgg accgcctcct
    14701 ccatagatgg agtggctgaa gaaggacata ccgacggaag tacccatggc cctgccatag
    14761 tctacaccgg gcaggctggt ctcgtgctcc accaggtcgt tgtagtatag aatggtggac
    14821 ggaacaccct gagcggccct tgcggcaccg atgttcacgc agatcgcggc cagcatacca
    14881 gcggacacgt aagcgttcca cagcgggtag tcggtcgtga catactcaac gaatccggac
    14941 gggaacttct ttcccttctt gatgaccttg tcctctaggg cgcggccaac catggaagcg
    15001 acgacatcac cgacggtgcc ggtcttgccg ttctccttaa cccagctgta gaccaggttg
    15061 ttggcgttca ggccctgata ggccagggac aacaggtgct gtctctcaaa gtttccgatc
    15121 gcgtcaccca tttcgtaggc ggcggcggtc tcgtagatcg aggagagagc agcggcgttc
    15181 atggcgttcc ttccagtcag catgactatg tggttggcca tgatgttcct aagggcgtat
    15241 ccagtaccct cgttcagctg cggtacatcg agaatgcttc tcaggttgga tcccagcatg
    15301 ttgatggtct gcgggtatct gccccagaca gcggccttga ccatggacgc ctcgaacatg
    15361 ttcacgtcga actggtcgat gatggcctcg gtcacggcgg cggcaacggt ggtgaatcca
    15421 gtggtgtact cggcaccgga atccatcctt acggacggaa cggtgacgat catcctcttg
    15481 ccgtcagcca tcgtcttgac ctcggagtcg tcgtcctttg aggccctgac gatgtcagcg
    15541 attctcttct tcaacttgtc agcgttcgcc actactgcga cgtccagaac cctgcctgga
    15601 acgttcaatc cgccaaccgc tccggtcttg agacctttct caataccctc gaggttgaca
    15661 gcgatcgttc tcttagtcag agatatggtt cgcttaatgg cggcgttgtt taacggactc
    15721 aatgcgtcga gaggcacgtc tttctcgatt attttgcctc tgtcgtcata caagtccacc
    15781 ttgtccttgt attttgccat tttttacctc ctttcaatag ctcggtcccc tcaagcagat
    15841 ttgcatcaat cctgagaaaa ccggtacccc ttgcggactc gacaatgtat agttagaata
    15901 taagcttgat gatggatgga gtatccatcc atgttaaaca atagcttaat ttttgtcgca
    15961 ccccagacaa aaaccgtcga gttttaacgt cctaaaattt tttaatattt aaaaatttaa
    16021 taaattatag cttttcattt ttaatatatt ttcaatgagc gttataataa tatttatcgc
    16081 atctcgtaaa cgctcttaat gagttttagc acggttatcg cgtcctcctt tttaatatct
    16141 cggtaattct ccgcaaaaaa ccggtcgaat gcttcggcat ccttgccgtg taatgtccgg
    16201 tgggcaacct cgagaaagac cgggacggtc cggcggggat aatagatcga tcgcatctcg
    16261 tccaatatct tggccctatg gaccgaatcg atgacctcgg ccatccaggc cgcgtccaga
    16321 agggaccgca ggttcaccaa cggctcggac agtggctcca tggtctccgg gtcgaacacc
    16381 aatgccacct cgtcgtcccc ctggacctct ccgctggcgt acatcttgaa aatcctaccc
    16441 acgccggtca tgccataatg gcccatttca gccgcccgga gcgcccccat gctccccccg
    16501 ccgatcatct tcacctttcg attgagtaga gacaatatct cccgatggcc gaccgaacag
    16561 ctttgcagga acacgccgtc gatgataccg acgatctcga cgccttccag atgctgcagg
    16621 tcccccctcc tgaccggcgg acggtaatcg gcgtcaagta tctccccggc ctcggacaga
    16681 ggaaggcttg gacctagaaa aaccaccggc ctcatgccac cagcctcggc cccaggcggt
    16741 ccatgtccat ggcgaatatc tccattccag gtatgatgac ccgcaccaca ggtactttca
    16801 gctcaggcct ggtgagctct accacgacga ccttctcgaa accgccctcg accagatggt
    16861 ccaggaccac ctcgatgtcc tccaagaggt ccttggtgtc gaactccggg aagtcggaga
    16921 ttccgatccc atcggaggga gagaagtaca tggagttcat gcgcttcatc cgctcatatc
    16981 cgagcgtgcg gttcagatcg gccttggtgg tgtcctctcg agcgccatgt atctgcgtgc
    17041 atcggctctg ggccacctcc gtcaacgccc ggatcgccgc caccctgggg ctcagatgag
    17101 tgcccacccc caggttcaga agcgcggggt ccttcattct cacgtcgtcc gcggcggcgg
    17161 cgatggtggg aatgccgaca tcactggtga ggtccttgag gtgcacttcc acaccttgct
    17221 tgctgaactt ctccagaaga tcgcttacca ccgtgcagtc gtccccgacg actatttccc
    17281 cgcggggctt ccgcctagcc tcgcatatcg accaggcgtc tcgttcgacg acctcacaca
    17341 tggcgtgcag tatcgcctct tcgagattgt tgccggacgc cagtccgttg gtgttgctcc
    17401 tgaagagctg aaggtccttg ttagattcgt atggatggta caccgccccg gctggaaccc
    17461 agacatcctc gccctcaatg aggtcgtacc ccttgaccca ggcgatgggg tggaagttga
    17521 cgtgtacgtt gatcatctgc ggaaggatga gggaacgagg gtccacggcg ttctccgagg
    17581 ccagcatgtt ctccatcagg tcccgccgga ccttctcgcc cttcggttcg gcggagtagc
    17641 gctccatggc ctccatgatc gccgagacgc gcgcctgctc ccggctggcg cctttgccgt
    17701 tgtatatgga tatcgcccct tccttcgccc cgggccttat actggagaaa acaggtattc
    17761 cgatgcggtc caggtcggtt atgtccgcca cgcgggttat tcctgcgacg gggagcagcg
    17821 gctccacccg cttcagggtg gcctcgggac ttatggcccg gtgaccgtcc ttggtgtacg
    17881 tcttggcaac ggggtggagt tccatgggtg gggtgaacct ccgtagaatc aaaaagcttt
    17941 tgcgttatca gtcccgggaa gcctcgttct ccgccaacgg cagggccaga tcgaacatgg
    18001 cgtcctcgtt gatcggtatc ctttcgatga gaatgtcgac ctccacccgc tgcacgttcg
    18061 gaatgttgac gatcttgtcc tggatgaggt cgtaaaggct gtccacgctg ctggcgtaga
    18121 cctcgcagat tagagagtga tcaccgaaca ccttgtaggc gtactgtatg ccagggaact
    18181 tcttgagctc gtcgatcacc gcgcccagcg gggacccgac cacctgcagc ccgatcaggg
    18241 cgcgcatcag acccagcttc ccagtgttca cctgcatggt gtaggcgctg acatacccgt
    18301 cctcctcgag gcgggagatg cgcctgctga ccgtggcctt cgatacgcca agctgatcgc
    18361 cgatggtccc caggttctcc cgggagttct tcctcaacat cctgagtatc tcgaggtcga
    18421 tgaggtccat ggtaacgcct gcaaatttat tgcaagcaga ccattgtcaa cgctattata
    18481 ttgacctttg tttcaaaaat aatgaaaaag taaaaaataa ttgtaagaaa gttcgggatc
    18541 agccgctctt gatcttgccc ttctcccgga ccggcttgat cttctgcagg gcctgcacga
    18601 ccgcctccag tttggtggcc ggtatcccga ccagcatctc ggtcggctcc aggtcggtgg
    18661 cctttcggca gccgtagcag cctatggaca tgctcagggt gtcgtgcagg tacggataca
    18721 ccgtggaata ggcgcagctg gcctggaaag gctccagttc caccgttatc ttaccgccct
    18781 cgaagaactt ggcggccacc ggaagcagcc agtacatctg ctcgggcgtt ccggtcacca
    18841 cgatcacgtc cggcggcagc tccgccttgc tcagcgggga aacggccgtg gcgatgacgc
    18901 tcccacagtc cagctggggg cgctcgtcga tcatcttctt ggcggcctcg acgctgtcga
    18961 acatgcccag gttgtaatgg aattctccag acctcacctt gtcgggaatt ggtacgaggc
    19021 caagtgcgga cgccccgaca tgacaggcgt gcttatcacc ggtcagcaga agcttctcac
    19081 ccctcctggc ccgcatgacg gactggcaat gcctgatgtt cttttccggg acctgatagc
    19141 cttcgggcag cggctggccc ttcttcacca gggtgatcgc cacgggttcg gtcggcagct
    19201 ccaggatgtc catgatgatg cgagaacaat tggcgtaatc ggtcgtttta acacctgaaa
    19261 gaaaattgac gttaacgtag ttaatggttg gtatggttaa ctagcggttc atcgaacgga
    19321 acagacccag cgatcgtaga aggggtcacg ctcgttctcg aacaccctgg gcgatcgtcc
    19381 cttggcctcc gcccaggacc taagctgctc ggcctcctcc tgcgttccca cggtaaccat
    19441 gacctgttcg ccgatcagaa gcacctgctc gaaaattatc ttccagatcc aggagtttcc
    19501 gacattgata tccccggcca tcagcatcag tgcgaaaggc gccttctcca gatattgcga
    19561 taccttggcg gcgtccagct gggcggtgct ccaggactga agtcgcccga tctgcaggcc
    19621 gcggctaaga agcggggcgt ccacatcgaa ggcgaaggcg cgcaatccca ccttcgtcag
    19681 cgccatgctg cctaccccgg agccgcagca acaatcgtaa cagagatcgc cgggcttgaa
    19741 gttccattct ttccagatca ggtcggagac cttcttggtc cgatcttcgg gaacatcgtc
    19801 cagggccggc tccacctcgt tcatgatctt ccgagcgaaa tggtcgtaga ccgcctcgcg
    19861 gtacgtttcg gtatcgcagg tgtacacctt gatgtccagc tcgggaagga gctcgatgag
    19921 ctcgtccgac ggctccttcc agaggaagct gacggccttc catccgccgt cctcccgggc
    19981 catggccaag ggcgtctcgt cgttggagat caaaaggcgg acctgttccg atccgctcag
    20041 catctgggcc aggaacatat cgttccccag gtcctccagg gtgttctcca gcaaccggag
    20101 ttcctccagg tcgaaaagct cgcatagcgc catggcgagc gggtatcgaa gctgggatta
    20161 ttaataactg gtcaattgcg caataaaatc cgcaaaccga taaatatcct cacacactcc
    20221 ccttcaggga tgagagcgca gcccaggagg gattgggacc tctggtccat cgggatactt
    20281 tccctggtac tcatattgat aatatacgcc ctgccggaca gcgcgctccg tatcgtcatc
    20341 gggcttccct tcatcctgtt cttccccgga tactccgcgt tatcggtgct gtttccggag
    20401 agcaaggacc tggagatcat cgagcgggtg gccctctcct tcgggctcag catagccata
    20461 tccccgctgg taggcttcgg cctcaactac acccctttcg ggatccgcct ggcgcccatc
    20521 ctgttctccc tggccgcatt gaacgtggcc ttgagcgccg gtggcctcta ccgccgcgat
    20581 aaggccgagg cgccgtacct tccgttcgat cccgccgtgg tgtggaagaa gtactcgaca
    20641 cagttcaagg ccgagaaggg cgtggacaag gtcctgacga tagtgcttgt gatatccatc
    20701 ctctcgtcgg tcatcgccct ggtgtacgtg gtcgccgtac cgcgccaggg agagagcttc
    20761 accgagttct acatactggg accgggaggg aacgccaccg ggtatcccag gaacctgacc
    20821 gtgggccagg acgcctcggt catcatcggc atcgccaatc acgagcaccg tacggtggat
    20881 tacaccgtgg aactgtggct ggtcaacatg agcttcgtgg acaacgccac gcaggtgcac
    20941 gccatgtatt tcttcgactc cttcaatatc acgttggagc acaccgacgt cgatctggaa
    21001 ggggaatggc aggcgcaatg ggaactgccg tacgagttca acgtgacctt gggaggcaac
    21061 tacaagctgt ggttcctgct ctacaaggac ggtgcccccg cgttaccttt cgccgcatcg
    21121 ccgatgctcg attacaccga cacctcggcc gaggatagga taatcaaagc ggtggagaac
    21181 gaggtgcaga gcctgaacct caacctgcgc gtgacggaat gatcacatca cggtcagata
    21241 gcgccggtcg tactcgtcca tgagcgcgtc gcggtactgc ttttccgaac cctccggtac
    21301 tgccttgcgc tcctttgccc gaagcagaag ctcatcggcc actcgtttcc gctgcgataa
    21361 cttgagcttg cggacctcct ccatgatatc gtccagtccg gcaagctcca caagttgtcc
    21421 gttgaccagg agcttctcgc cctcgttgaa cgacagtccg gtgtcgcagc ccacgcagtt
    21481 caatttggga tcctcgccgc tcatatcagt tcgtaaaaag aaggcaaata tgataaaaaa
    21541 agggtttcgg tctacaggaa gtagaaccgg gtcttgtagg tgaggcagac gttgcccatc
    21601 ttctccaggc ggtccaggac cccggagtag cggcgcacca ttaccttgcc ctcgtccgga
    21661 agcttctccc ggagcaactt gacctcctcc aggagcttgt tggcgtcctc gacggagaat
    21721 atcttcttgc cctccacgga ggacgggacg ctggccacga tggcgcagtt gtacttctgg
    21781 gcgatgccgg gcagcgcgct gttctccggt ccgaaggtgc ccatgcagcc ccttccctcg
    21841 tcccaggaaa gcgggcactt gaggcaggtg gcggccatgt cgtcgaacga cagcatgtcc
    21901 catccagtta gacggtcgtc cttgccggcc ttggccatca gggcgctcag gcggtcggcg
    21961 ggcaccttgt ccaaggatat ccatccggtg tacatcttct ggctctcggc ggtgagcagc
    22021 tggcggtccg cttcgttctt gaccttctcc aggtacatcg tctccatctc cgggtccatc
    22081 cggttccgct tgaggaaagc ttcccagtcc gcgcccatca gcagcttggc ctggcttacc
    22141 ggcacgacca ggtcgaactc ggccaggtcc tcgaagcctg aaacgtcctt caggttgacc
    22201 ttcaaaagag tggtctttcc gatcttgcac aacgcactgt cgctgtctat ctcgcaaatt
    22261 gctattgaga ctcccattct atcccttcct gccgcgtatt acaaaaaggg cggtatatat
    22321 cgcttatccc cttaacgctg aaattgattt ttgtctgaca agaaggcctt gcccgatagt
    22381 cctggctggg atacggttta tatattgttg aaattgaata cctacgggga atggcaatgg
    22441 cagaaacgga cacgtggccc atggccagtg gcgattacgt tctggggaac gaagcatcgt
    22501 ctgtcgcggt gttgatcgta ggccgaggag cggtcgaggt accgccggag ctctaccgca
    22561 taaaaggcat cctgaagacc gagaacatcg gactggagag ggtcatagca aacatcatct
    22621 ccaatccgaa gatcagagtg ttggtcctat gcggaaagga ggagttcggt cattttccag
    22681 gagcggccat tcacgccctt atgaagagcg gcgtgaacga gcatcgccgt atcctgaaca
    22741 cccgttcggc catcccgttc ctgtgcgacc ttccaccaga tgccatcgaa cgcttccggg
    22801 agcaggtgga gctggtggac gtgatggacg actcgccggc gcaggagatc gccgcctacg
    22861 atccgatata cgagttctcg cccgaaagca gggaacggtt ggagagcacg ttgaggaagc
    22921 tttcaaaaag gaaatactcg ccgttcccag aaaaggccat gttcgtccgt tccaaagcct
    22981 tcgtcgggga aggggtcagc gtagccaagc aacttcacct ggcctcggat gatttcatca
    23041 ctcccatgct ccgccttcct tcggacggct tgaacacgga catgggaatg gtcctgctgg
    23101 acgaagagtt cggagtggtg ctcgagccgt tgcagggccg gataattacc gtgccgtccg
    23161 ttgagctggc attgcgattg cgttcctatc tgacggggtt ctgacatgta caagttccaa
    23221 accgcgcagc gtgaatttag cattggaggc gtgaaggtag gaggacagcc tggtaagagg
    23281 agggccatgc tgatcggttc cctcttctac ccgaggcact cggtggtcct agacccccgc
    23341 aagggcgcgc tggacaaggg aaagctgaac gaaaggctgg actgctatct tgcaacgatc
    23401 gacaattgcg gttgcccctc cggcctgatg ctgtatgcgg agagcgttga tgccgcccgg
    23461 gcatacctgg aagcggtatg cgacaaggtg cccggaccgc tgttcgccga ttccggcagc
    23521 gccgaggtgc ggctttcatt cctcagaagc gcccaggaga tggggatact ggatagggtc
    23581 gtttacaaca ccattaacgc tggactttca gacgaggaga aagaggcgct aagagcttgc
    23641 ccgccggtga acgcggtagt tctggcgttc aacccccgcg gggacgacgt caaaggcagg
    23701 atatacatgc tcgagagcgg ggacgatatc ataccccagg gactggtgac atcggcggag
    23761 gagctgggga tcaagaacct gttgatagat accgcggtca cctctccaga cctcagcgcc
    23821 ggatcggcct tgcggtcgat actggtggcc aaggccaagt ggggtctgcc taccgggtgc
    23881 gccttgcaca acgccgtgga atgcctgcga ttggacggtt tggaggaccc caaggaagct
    23941 cggagaagcg tggacgcctc ggctgtggcg atcagtatca tggccggggc ggactatgtg
    24001 gtctatggtc ctctggagta cgccaaacga accatgcccg tggcctcctt cgccgacaag
    24061 atgatggagc aggcggccag ggacctctag agctcgatcg agcaccccgg ccctaacgaa
    24121 aggaaccccg ggaagcggtc cgagaacagc ttggtggccg cgaacccggt gcagtgcatc
    24181 ggagccacct tgtttacgcc ggttcgcttg accccctcaa tggtcttcag cagcagttcg
    24241 acgtccgccc ttcccaaatg aaaaccacca gcggccatga tcaatcttct cccggtatgc
    24301 atgctgacct gggtgagggt gttcacgatg cccggatgac cgcatccggt gagcaccact
    24361 aacccgttcc gggtggaaac gcacaatgcc tgctcctccc tgatgatgtc ctgggacgtc
    24421 ccaccgtccc gctcgatcaa aaaggatgcg ggcctttcaa agtccgtcct tctgaatatc
    24481 tcaccagatg tgcctattcc ctccacaagc tctttcggcc ggtcatcgta gatcggcgga
    24541 tgttcgttca gaaggggtag aagctcggcc gatggtccga tctcctttcg atcgcctgag
    24601 gtctcaacga aacgacgccc ctgaaaggtc aggggatgcg tgtgcaccgg gaccccttcc
    24661 ttgaccagga gcggcaaccc gcccagatgg tcgtaatgcc cgtgggaaat gaagaccgcg
    24721 tcgatgtcct tcggactcat tccgaggagg tcgagattgt gagcgaacac cttttccgac
    24781 gaaccagtat cgaagagaac ttttttccct tggtcggtct ggatcaaaag ggaaaggccg
    24841 tgctcggcaa ggaagtcgcc gggggccttg gaaataaata ataaagggtt tgcggtgccc
    24901 gcgtggtcgt ccaccaggca ggtaagtcgc acctacgcgt cctctccctt cttcacgatc
    24961 ttcagggcac tgaagtcgta gacgctctcc ggacacaccg actgacattt cttgcacgcg
    25021 gtgccaaggc agtgctcggt gttgacccgg atgaggaact tcttgtgccc catggccgag
    25081 acctgaaggg cgcattcggg acattccttc tgacacttct tgcagccgat gcatccttcg
    25141 aaggagccca tgagataaac gcccacatcg tccagggtct tcagtccgcg agcgccgatg
    25201 accgggatat cggacagcac caggcggatg gtctcctttg gacgtacgat atcaggcagc
    25261 ggacgcagac cggcgatctt gagcatatcg ttgtacatgg tcatggacat gccctcggtc
    25321 cagtaggcga tctcgttgac gtatatgtcc tcgaacacct tgctggtggc gaacatgatg
    25381 tgcttgctgg agatggcgtt ggccacgtcc tgcatgttgt cgaggccgtc gtcgtccacc
    25441 aggatgtcgt atgacatcat gagggaggtg ttgccggcct gcacggtctt atctagcacc
    25501 ctcgggatca gcccgacggt ctgcgccttg atcggatcga cgtacgtacc ggacgctccg
    25561 gccatgtaca tggtcctgat atccgtgtcg tccactccga cctcctctat gagagtgcgg
    25621 tgcccggcgc ggatggcccc ggtggccttg ccagcctcgc gcacatcctc ctcgccgaag
    25681 tatatgccgt tggtgaggtg gatcttgcgg tcgggagtgt ccacgtacgg cagcttgatg
    25741 accccggtct ccagaccgac cgccatggcc gccacggtcc cggtgccggt gatgccccgg
    25801 gcgaccaccc cgtccaggcg cttctcgtcg ccggtgcgcg gatggaccag ggcggacctg
    25861 accggatgaa gcttgtcgtt gaggaccacg ttgtaccagt atccgtcctc gccgggaatg
    25921 acgtcggata tggcctgcgg ggcggcgagc ataccgaagt cgatggactg accctccatg
    25981 gccggaccgg ccgcggcgga gccggtgtag agctcgccct tgtagaacag tcccatctcg
    26041 gcgttggtgc cgtaatccgt gaccatgcat gtctccttct tgtccatcat gccggtcttc
    26101 attatcatgg ccaaggcgtc cgcgcctatc tcgtggcgga tggacggagg tatgcgaacc
    26161 tcagcggtgc gcctgaccga acgcatcccc agctcctcgg ccttgatgga atgggccttg
    26221 cgctcgggga ccttgacgtt cagccgcttg aggatcgact gcccggcgta ggccaggtcg
    26281 cggatctcga tcttctcgaa catggacatc tgggcggggt ttccgcagac ggacacccgc
    26341 tctatctcct cgggcttggc gcccatggtc tcgatcagct tgtccaccgt ctcgatgact
    26401 atgcggtggc cgacctccga gccgttctcc atccagaaat gcagatggtc catgatgttg
    26461 gccccgggca gcgggtgcct catggttatg gccgtagcca ggatcttgcc cttcttgtcc
    26521 aggtctacca ggtgcccccg gtaaccgcta gtacctaaat ccagcgcgac tcccaatgcc
    26581 atggataacc tcgaggggag aatgctatcg tcggatttat aatactgttc cctttttttt
    26641 agtgtcatat gaaggttggt ccagcctgtt tggtatatca taccgatcat attccattga
    26701 caacgagatt tatactcgat aggtcgttaa cggccctagc gtgattacat gaggatcgcc
    26761 caggtaaccg gtttcttggg gagcggaaag accaccttcc tgatcgaggt ggccaaggag
    26821 ctgaactcgc gcgggttgaa ggtggccacc atcgtgaacg atgtcggtca catcaacgtg
    26881 gaccgcaagt gcatggaggt gcacggcatc gataccatgg aaatttctgg cgggtgtatc
    26941 tgctgcgagg tgcagggcac cctgaccacc acggtgacca acatctacat gagcttcaag
    27001 ccggacgtga tactcgtgga gccgaccgga gtggctattc cgctcggcct caaacaggcc
    27061 gcggcgcaga cggtgaagaa gatgcctaag atcttggaac agtcaccgat agtcaccttc
    27121 gtcgacgcca tgcgcatcga caaactcatg aacaacgtac gccggctggt ggagacccag
    27181 atcatagagg cggacgcggt cctcatcaac aaggtggacg cggtgagcga ggagcgcctg
    27241 cgttccgtga cggaactggt caaagggctc aacccaaacg ttcggctgat ctatggttcg
    27301 gcacggaccg ggcagggcat taaggaggtg gccgacctga tggtgaacgg agaggcggtg
    27361 gtctacgacc tatcggacgc cgaggaccgc ttcgacaaga agtacgggga gtgattcgat
    27421 ggaccagaag gaaaggcagc tgctcacgca ccgggcgtcg gacgagctgg gcaagttctc
    27481 catgtgggtc cggctgtaca tcaaggaccc cctggacggc aagaggtccg aggaaatggt
    27541 cctggacctc atgaacggca tcaccaagga atgcttcgcc cggggggcgg acatgatcgg
    27601 gcacgtcaag tcgttcctaa ccgccgaagg aggttccacg atttcggtga gcctcatcga
    27661 cctggacatt ccgccgacgg tgcagaaccg tttcgacggc accaagatga tgcgcggcga
    27721 gctaatcgtt cacgtcatcg tgcacggcct gtgggaccct caggtgcgcg agacatccct
    27781 ggagttcacc aaggggttca tggccgagcg ttcgatcgac tacgaagtga tcaacgactt
    27841 ctacgaaaag gagaagcgcg tcaaggactg agcggtaaag gatatctaaa gagcatttcc
    27901 attaggggaa catgttaccc cgggaaaggt tcgaggcagc cttcgagagg gcgccggtcg
    27961 accggccgcc gataatgtat caacaccttg gagcggcgag gaccgttctg aacgccgccg
    28021 ggctcaccat gcgagagggg ttccacgacc cggagaagtt cgccaagatc tgcatcatgg
    28081 cccagcggat caccggcttc gacaacgtga tggccggctg gggggacatt ttggtggagg
    28141 cgagagcgca tggcaccaag tggaggtggc cggaaaagga ctactatccg aggtcggacg
    28201 ggtacgccat atcctccctg gcggagctgg acaaggttca accggtggac cccatgaagg
    28261 acgagttctg gtccgttccg ctccgggccg cggggttgat gcaggaacgc catggtgacg
    28321 aggtggcggt ggtcggctgc atcaacgggc cgatgatgat gagcggggag gtcatgggat
    28381 acgagaacct gctcatgtcc acttggtccg aaccggatct ggccttgcag ctcatggacc
    28441 ggatgctgga gtcctcggct atgtacggcg aacatctggg gaagatgggg atcggccacg
    28501 tcttcattga agatggcacg tgctcgcccg acgttaactc catagagggc ctggagaggt
    28561 tcgacctagg atgcctgtcc aagctcatgt cctcgttccg ttcgaacggg ctcaggtcca
    28621 ttgtgcacaa ttgtgccgct aacccgtatt tggatggcta caccagaatg gagatcgaag
    28681 cgctgcacct cacccccaag accggggacc gccggaccat atacgacatg ttccgccaga
    28741 ggacgacggt catcggcggg attgaccaga ccttcctcct cttcaaaggc accccggagc
    28801 aggtgcggaa ggaggtccag gcgatgatat ccgattgggg ggatggtccg ggattcatga
    28861 tcgccccggg ttgcgagatg gcctttaaga cccccatcga gaacataatc gccctccgag
    28921 aaggatctgt aaagaacgtt aaagacattg ggaacgacgg ttaaacattt gttaatagta
    28981 tacaatcgtt tcatttggcc tgaacttagc cagatgctaa taattaacca gcgttaaatg
    29041 gtgttccata ttcttctatc cccgatacat taatgtatag aaaattagat actcggaaca
    29101 agtcagtttc ctactgaata ttaggaggaa ttaatttgtc tggtaagatg actccaaggg
    29161 acagggtatt ggatgccctt aagggcaaga agcatgacag accgccggtg gcagttttca
    29221 cccagagcgc aaccatggga cagatggacg ccctaggcgt ttcctggcca gaggctcatt
    29281 acaacgtgga catgatggtc aagctgggtg ctggacaggc caaggtcttc gggttcgagg
    29341 ccgtcagggc cccgttctgc ctgaccgtcg aggctgagag cctgggtttg accgctgaca
    29401 agggccgcaa ggaccggacc ccgatgttga agggccaccc gcatcagatg gaggacgagc
    29461 cagccctcat ggacgtggga accttcctga agaccggacg cgccgcgatc tgtcagcaag
    29521 ccatcaccaa gatgaaggcc gcctacggcg ccgagtaccc ggtcatcgcc ggtaacaccg
    29581 gaccgttcac cctggccggt cacctggtca gcaccgagaa cctggttctc tacatcatgg
    29641 tcgagccgga actggtgcac aagtgggtaa aggccgccaa cgtgatctgc aagggataca
    29701 gccaggccct ggccaacgcc ggagccgatg tcgtgcagat gtccgagccg tccgccagca
    29761 ccgacctgct gtccccggac atgttcaacg agtacgccgg tgcctacatc gccgactcct
    29821 tggccccggt caagggagcg actggcgttc tgcacatctg cggtaacacc accgacatcc
    29881 tgaacaacat gatcaacacc ggatgcaagg ccctgtccat cgaggagaag gtcgttccgg
    29941 aagaggcggt caagatcgtc aaccaccgcg ccgccctgat cggtaacgtc ggtgtcgtca
    30001 acccgctgct gcagggaacc cccgcggacg tcctggccca cggaaagcgt tgcgctgccg
    30061 ccggcttcga cgtggtgtct ccgggatgcg ggctgtccgc ccttatctcg aacgacaacc
    30121 tggccgcgtt ggtcaaggcc gtcaagggct aaaagccctc aaatcctttt ttccttttcc
    30181 attttttcat tttttcttgt tctaagttaa ccgtccaatc ttgtaacggc aataacccta
    30241 ttgatgggtt cgggcctaat caacattaga agcaccagac aagagagata acttccgagg
    30301 aggggccgag gccggtctgg aagcagttca caaaaagttg aaataactcc tgcattaaat
    30361 cctctgcgtg tccttccaag tgcttttcat atgcacgcac aattcagcca gaagccagat
    30421 ggccgaggga ttgaccaacc gctatttttc ggacacgatt accgctttca gcgccgggac
    30481 gaatcccggt caggtccacc ccatggcgat aaaagtcatg gccgaaaaag ggatcgacat
    30541 ctccgggaat cgatcgaagc acctcaacga gttcaaagag caggatatgg acctggtgat
    30601 caccgtttgc gacggagcga acgagatctg ccccttcttc ccaggagcga aggaccagga
    30661 gcatgccgga tttccagacc cggctgctgt cgaaggcccg gaaaatgaac ggatggatgc
    30721 gttccgccga gtcagggatg aaatatctga tttcattcta acgcgcttcg ctgggatctg
    30781 aaccgcgaag tgaagaggta aatcaccgga caacttactt ttttaccttg gccaccgggt
    30841 caccagtggc ccgggcgacg atatccaccc aggcggtctg ctccccctcc acgttatctc
    30901 cgccatagaa cttcttctca taggtgtcgc tgcgaactcg gatgttctcc gccccggcct
    30961 cgtacacctt gttccgtacg tactcctcgg cctgccggcg ggcggcgctc accgcctgct
    31021 ccacatgccc gtaggtcacc ggagttccga agggacctag gacgaagaac agattgtcca
    31081 tgttagggaa cacctgcgcg gtcaccgtct ctgatatctg actgcatacg gcgcccacgg
    31141 cgttcccgac ctcgtggtcc ttgggcatga tgacctccac gttcattcgt tcctcgagcg
    31201 gcggcatgta gatgtgggtc ggtgccccga tgcccaccag cggccggtcc aatcccgtac
    31261 tgttggtgat actacttcca ggattgccgt tcaccatgga acgcaggagg tagttgaaac
    31321 caggaccttc agacatatcg cccgattcgt ccagtaccac cttgcgcatg atctcctcgc
    31381 ccaccagggt gatgaactcc tcatggaagg acctgacata atcatcgaac gatttgtggc
    31441 accagttagc catgaactgc acgcccgtgc gggcggcctc cttatcaaaa cggtcgaagt
    31501 agccctgcac gtgcatgaaa tccgtggcgg tcaggccggt catctgcagg aatccacggt
    31561 ccttgaggtg cttgaccacg tcccgatagg tgaatatctc ggaattgcct aggcgtatct
    31621 cctccagagt gctgatgggg tgcgccctga cgaactcgta tatcgccttc tccttggcgg
    31681 aaagcttggt ggtgcccctc tccacgtgaa gataatagtt cgtctcactg gtgtcgttca
    31741 ttcttcctat gatctcagga taggacgagg cggccactga cagcggcacc acgcgctccg
    31801 gcccgacctt gaagttgcca cgttggtccg acacgacgtg cgaatctccg cccagaccca
    31861 cggtccatat gtcgatcgct cgcaccctgg tacgccagtg gccgacggtc gcgccctcct
    31921 tcgatatgcg cggaaatccg tcatccaggt aagcgatgtc cgtggacgtt ccacctatgt
    31981 caaccactat gaagttgtcc ttcttgcaga gcagcttgcc gcccatcagg ctggccgccg
    32041 gcccggaaag gatggtctcc accggcctct ccctggcctt ctcgatgttc atcagagtac
    32101 cgtccccttt gaacaccagt atggtggcgt cgacacctct ttccttcagg gacctttcca
    32161 caccgtccag gaattcggag atgatgggaa gcaatcgagc gttcagaaca gcggtgacgc
    32221 ttctttccgg aacgcctaac tgcgaggtga ggtgatgccc cagcaccact ggcaatccgg
    32281 tacgctgttt gatcatgcga gaggcatcca cctcgtgggc cgggttgtaa acactgaaat
    32341 ggccggagac cacgaacgaa tcgacctcgg tacgcatcgc atctatggcc tcctccagag
    32401 ccttggtgtc caggggggcc aattgttgag cgtacacccc gtgaccgcct ttgatgtagg
    32461 catccatgtc cgcgcccgac ctgaaatccg acatgggcgt ccaaccgata cctatgtgcc
    32521 cgacctttcc cccctttcca gtgagtatgg agttggtagc tagcgtggtg gacagcccta
    32581 cgaactgaat gtcccctcgt tcataggcgt cactgttcag cgcctcgtct atggcgccga
    32641 gtatgcctat ggataggtca tgataggtgg tttgggactt gcctttggcc aatacctcga
    32701 gggtgtccat gtccactatc gcggcatcgg tgtatgtccc accagtgtcc aatcccaatc
    32761 cgagtcgtct agacgccatg tgtatctctc gcggaatgca cgaaggccca gatataagat
    32821 ttggcgcttg cttcagagca gtaaggctat cggcaacagg agcatcacga aggccgccgc
    32881 cgcggtaccg gccagcttga acctcgcgga tatcccgtgc gtcctggccc agcacagcag
    32941 agcgatggag gccaggagtg cgatctggag gcctccaagc aggacatatc tttcaccgac
    33001 gccgctgaaa tcatctatgc ggatgttgac ggccatgagg ataacggcta ggccctccac
    33061 ggcgatgaaa gccgttacca acaggaacgt cgatgaaacg atgcgcttcg gccatctggt
    33121 cagaaggggg ctgtccttga ccaaccaggc catcgccccg atgaccgaga ggaccagcaa
    33181 ctgaccgcct gccaaacgga aggtgttttc cagtatgccc cccagccctt cgatgtacgt
    33241 gttggcggca agggccatgg cgaagacgcc ttcgaaggcc agtaaagcca atgccatggt
    33301 gaccaggagc acgctgaggt agtgcctgtc gagccgctcc ttgcggatct tccaaagcaa
    33361 gggagagatc aaaccgagac cgaacaactg agataccccg gcgaccacca ctatcttgct
    33421 cacgctgccg accccgtcca cggccaccgg gccgacgaaa taagtagcga ccacgcagac
    33481 ggcggatatc gcgccgccaa gaacgatcat gatcaccata ctgggccatc catctatcag
    33541 cttgcgcagc tttggaagtt tggaaacgac ccagggatca tagggcacgg tccataggac
    33601 caatatcgct agaccgacga ccatcaagag cagcccgcca ttagctatgg tgctttcctg
    33661 gaatccggtg accccgatga tccgggtggt accggcgatt ccgtaagcga ccagcccctc
    33721 aacggctatc agcgcggcgg cgatctgccc gaacgaatcg gtcagccagt tctccgatga
    33781 gatattgcgg atcctccata agcgcaacga aacgataccg atgccgaaaa gctgggcacc
    33841 gacgagaacg atccatttct tccctatccc gccgaagtcg gttatgaaga cgttgccggc
    33901 aaggaccgcg atggcgattc cctcgacgac caccatggcc atggccaggt aggttagaaa
    33961 attgagcagt ttgatcaaga tcggtttctc taggtcgggg aaggtcatct ttacagccca
    34021 catggcggag atgaagatgc ccagagcggt caactggatg gcggcgagtt gaagcgtcga
    34081 ggccctgacg cctccgatgc cgtcgatgct ggccgaattc gccaagctca aggcgaagaa
    34141 gccctcgaaa gcaatggccc agcccaatat gatcccttgc aatgttcggc tggttatacc
    34201 cttcatacac taccccggct tctcaagata ccaatctctt tgattataca agttccgcat
    34261 taattatggg ttgatggacg tccgagacca ctcaccaggg aagcttacga accgtcctcc
    34321 ctatcggcgc ttgacgtcct catgtagagg tcgttcaccg tctccagcga tctctgcccc
    34381 tttagggtga gagcgtaatc gcctcggccg cccttctgta acaccatgcc agcaccggtc
    34441 agcctctgca gatggaagag caggtttccc ccgcgcaggt tagtgagcga agatagctcg
    34501 gtgaacgaac gctgagaccg gctaagggat ttcattatca gcatcctctg ggggttggat
    34561 aatggttcta ggaggtcccg cacaacttct ccctccggca tctcatcgat gctgtgccct
    34621 atttcctcct tgctcctata gagccgaagc tgccgcatca gctccgtctg gtcctggaac
    34681 agcgaaccga cctctcggaa gcatccgtcg catctccctg tcacggcatg ggacctcagt
    34741 gaatccaatt ttttctgttg cttgtcgaga tcttcgtccg ttacgcgcgg cctctcgagg
    34801 agggccagat tctcatccaa gagctccatg aacctcagac ggcaatcggg acgcatatca
    34861 cacctttttg ccatccccgc atccaagcgg ctctccgctt tctttcgtac ctcgcccctg
    34921 agcagatcaa agagctccgg cccctgggca tcgtgatttt gtgagctctg tagaagagtg
    34981 cttatgtaac gaagctccag ccccagctca tccaccttct gtttgagctg aacgatctcc
    35041 tttcccactg cgctctcatt gatgggcata tcgcaccgat gcataattat gaccaaactg
    35101 tataagttta tgcaccaata taattatgta taatttatta ttttaataaa aggtcataaa
    35161 aaaaagaaat tgggggcgat gccccgttag ttcttcagga gcctgatcgc ttcgcggacg
    35221 gcttcgttgg cgtcgtagcc ccagccgtct gcaccgatgc tcttggcaaa gtccgcggag
    35281 gtggcaccgc cgccaaccat ggtctttacc tttcccttca taccgccctc ggccagcatc
    35341 ttctcgatct ccttcatgcc cgccagggtg ggggtcatca aggtggaggt cgcgatgatc
    35401 tgggcgtgct cgtccttagc cttctgcacg atgtccttca ggggcacgtc gcggcccagg
    35461 tcgaacatgg tgtttccagc gccggtcagc agggccttga cgatgttctt gccgatgtcg
    35521 tggacatctc cctcgaccac gcagaggact atcctaccag cggcgtcagc ggacgcggtg
    35581 tccagcttcg gcagggccag gttcaatccc tggtacaggg tctgggcgga cagcaggacc
    35641 tggggcagga agtactcctt cttctcgtac ttctcaccga cgatctccat tgccttgctc
    35701 aaaccgttga agatgatctc ctttgcggag actccggcgt caaggagctt ctgggtctct
    35761 cccttggctt ccttgatcct ccccttaacc actatgtcaa tcaataggtc catgtttgtc
    35821 attttagatt tcctccaaag aagttttctg cgtccaaatt tcaatcgaga ctaataaacc
    35881 cttggatgga tggatgagac atccacatgg ttttcaatgg atggattata catccacgta
    35941 atcatgccat gcactattgt taaggccgtt tatatttgaa aaatccattt actttactga
    36001 ataatttttc cctaaatcag gtctctatct aagtcgtccc tgagcttctt gaaaggatag
    36061 gcacgtggtt cggaaaaggc tccggtccaa ttaaaaaaaa ggtactgacc tatgaagagc
    36121 accatctacc gaccgtggat caataatcat catcttcgtt ctgggatgcg ccacagaccg
    36181 ggcacttgtc ttgattcttc ttcaagatac atccacagac gatgcactct accaatctaa
    36241 ccctcgacta tattatgggt tatgaaagta attaattttc ggtccgattc ataaattgtg
    36301 gaagatcgat catctgcgaa ttcttgccca ctaaagcatg ctggtcaccg ttagcgaaag
    36361 tccttcttcc agtccataac gaggagcgta accgagcagg cggcgagcct ttccgatgtc
    36421 ggcaagggaa tgcttgatgt cccctttcct ctcctcgagg tgcacgagtc cgccctcctc
    36481 cttcttcccc agtaccttga gcaccaggga tgcgagctgg ttcaccgtca ccttctcctg
    36541 attggccacg ttgaacacct cgccatgatg cttctcgtcc gtggcggcca gtatgttcgc
    36601 ctgcaccacg tccttgacgt aaacgaagtc cctggtctgc tccccgtccc cgaacaccgt
    36661 tagctgtttt ccggccttgg cggcggagat gaagcgaggg atcaccgctg cataatccga
    36721 tgagggatcc tgccttggac cgtagacgtt gaagtaacgc aggctgcagg tcggcagccg
    36781 atagttcaac cagaagttcc ggcagtacat ctcgccggtc attttggtga ccgcataagg
    36841 ggagatgggg gctggtaggt cgtcctcatg tttgatctcc gatggagcgt cgccatatac
    36901 ggcggaggat gaggcaaaga ccaccttgcg aaccttggcg tcccgggcct ccatgagcac
    36961 ccggagcgtg ccgcacacgt tcacctggtt gctggacact gggtcgtcga cgctacgcgg
    37021 aacggatgcg atggccgcgt ggtgaaagac gtagtccacg ccctccatcg ctccccggac
    37081 cttatcggca tcccgtatgc tgccggtcac aagttcaacg tccagaccgg ccaggttact
    37141 cttctttccc gtggtcaggt cgtccaggac caccacttcg ttctcttcgt gaagggcctg
    37201 ggcgatattg gaaccgatga acccggcgcc gccggttatg agcaccctct tatcttttat
    37261 ggttcgcata gtggacatga cggaaaaaca gtggacgcta ttgaacctat gcccttctag
    37321 gcctctttgc ctggtccttg accttgccca gcctgatgag accgatgtca ctgcagccga
    37381 acacctgagc ctcgcccatg tccaaccccc gaagtccggg cgatagcaca tcgccggcca
    37441 ggagagcgct gacatcgttc cccgaggcca aggggctgaa ggccggaagg accagcactt
    37501 cggcctcctg atgatagagg aacgccggaa gcttgacgta accgcccacg ccgtcaaaaa
    37561 ggcgggcgga ggggtgttcg tgcccctgca ccatcggccg tccgggatgg gcgatgtggc
    37621 catgcgagag gtgtatgccg tccaccaccg tttcgtcgac caggtcaagg cccatgctgg
    37681 aggttatggt ggccagatag ttatcgtgat ttccgcgcac cacggtgatg tcggcgatgg
    37741 agccaagatg ttccagcatg ccccgcacct gagaccactc ctggtcgagg ttacgggaga
    37801 actcgtgctt gacatctccg agcaatacga tacgcttcgg agggtcggcc tttaccagct
    37861 cgtctatcct ccgcttggtc tcccgggcct gggaacgggg aagctgcatc ccttctagct
    37921 ccaggctagc ctctataccc aggtgcaggt cccctagcac cagggtgcgg gaccgcagga
    37981 gcatggcgca tcgcccgttg aacatgcgaa tgtcgggcgt tacgtcgata tgcagcatac
    38041 ttccccgaag gtctcaggag ggatatcaat cccttgcaca ttttcgaagc tggggacgat
    38101 aggatattat acggaagctc cgctgaaagg gatatgatca ggcgcacctt ccttctactt
    38161 ccgggcatcg gacagctgaa ggagcgccgc ctgtgggaga gcggtgtgct gtcctgggag
    38221 gagttctttg agaggagaca tctcactggg atctccgttc agaggaagga gtgcctagac
    38281 caggaactgg ggacggccaa ggacctctgg gaccggggac gcactgaata cttcaccaga
    38341 cttctgccgt cgggacagca ctggcgcatg tatcaccgtc tcaaggagga caccgcgtac
    38401 ctggacattg agacgaacgg gctgggcccc ggagccataa taaccatggt gtccgtgcac
    38461 cgtcagggcg ggacgaccac cctgaccagg ggaattgacc tcagctcgga gaatctgacc
    38521 aaggcgctct ccggcaccaa gatgctggtc acattcaacg gcgcctcgtt cgatctgccg
    38581 atgatcgaga gggagttccc gttcgccgtt ccaaaagtac cacattacga ccttaggcac
    38641 gcctgcccca aggtggggct gcgtggcggt cttaagcagg tggagctgct ggtcggcctt
    38701 cgccgcccgc aagaggtgga gtacgttacc ggcgaggagg cggtctacct ctggcatctc
    38761 tgggagcgca agggcaacga gaacgccctg aagctgctgc gccgatacaa ccaggaggat
    38821 acgaagaacc tggagccatt ggccgaagtg gtctacggaa ggctggagga gagttcgctc
    38881 atggggtgcg ggaaatgacc ggggacgccg aggccttcgt agaaagggca aagagcctcg
    38941 cggctcgggt caggaaggcc aggtcggtgg ccatattctc gcacatcgat gcggatggcg
    39001 tatcgtccgc ggctatagcc tatcgcgccg tggaacggat gggagtgaac cccaaggtcc
    39061 attttcttaa atcactgagc gacaaggaga taaggttcat caattcctgc gacgaagaac
    39121 tgctctgggt ctgcgacctg ggggcgggat cctataataa tttagatcag tcacgctgca
    39181 taatcacgga ccatcaccac atattcggga gcgggcaatc cttcctggaa ttcttcgggg
    39241 ggatgcagaa catgctcaac cccgtggagt tcggattcga aggctcgtcg cacctcagcg
    39301 gagcaggttg cacctacttc gtggcccggg agcttgatcc ggtgaacgtc gacctggcat
    39361 acctggccat agtcggcgcg gtgggcgacc tgcaggacaa gcgggctcga agattggatg
    39421 gcccccttca ctcgacggtc atagaggacg ccttggggac cggggtcctt caggtgatga
    39481 aggacgacct gccattcttt ggctgggtga cccggaccgc ggtggccatg atcgccttct
    39541 ccaacgacct caaggccata gggtgcgagt gcaccttcag cgaggtcgga caaatgttca
    39601 aggggcaggg agtgaggacg taccgccctc aacgagacga atccatcaag gacgagaacc
    39661 tcagcaagta ctacagctgg tccgagcttg atagcgaacc tcgaggcaag ataaagatcg
    39721 cgctcatgga ttcccttcag aggatgggca aggacccctc cgtcttcgag ggcatgctgg
    39781 gagatgtcta ccttttccct aggttccctg tcggctcggc cagtcgggag gccaaggagt
    39841 tcgccaccat gctgaacgca tcagggcggt atctccattc caagagcgat gccgccccta
    39901 gcgagacggt cgtggaccag caggcggtga cggaggtcga agagaggagt ggagggttcc
    39961 aaggggagct gataatcaag gcctgcctgg acccagtgtc gttctcctcc gacgccatgg
    40021 ccaagctcgg gaatcatcgg gacaacctga ggaaggggct cgaggagatc cattcgatag
    40081 tggtcatgga ccacatccag tacatcaaag gccggataga cacccctgag aacaagaaca
    40141 agtccaagta caccctgacg gtcgaggata ccatcctagg gatcatcgta ggcatggcct
    40201 tggaacagag gccgaacagt aatagaagca atctttccgt tcgcgacgat atgcccctga
    40261 tcgccttggc ggaagcgtcc cctgattcag acacgtcgga gccgatcgcc accgatggta
    40321 atatgggtgc gccgggggag cgggtcaagg tatctggtcg catgaagcga gatctgatcg
    40381 ataagggtgt tcatctaggc gaggcgatga aacaggcggc gttgaaggta aaaggggcgg
    40441 gcggcggaca caacgttgcc gccggcgcca ccatccccaa gaggaagatc aaggcgttcc
    40501 tgcaagccct ggacgaagag gtgggggggc agatggcccg cttcacccca tcagagcgac
    40561 catgatggcc ttctgaacgt gaagccggtt ctccgcctgg tcaaggacca ctgaggcagt
    40621 gctgtcgatg acctcgtccg tgatctccat gccccggtgc gctggcagac agtgcatgac
    40681 gatggcgttc ttgtgcgcca cggacatcag gtcggcgttg acctgatagg gcttgaatat
    40741 cttctccctc agcttctgct cctcctcctg acccatggat acccagacgt ccgtgtaaac
    40801 gacgtcggcg cccttggccg cttccttggg ggattcgacg atattcaact ggcaaccgtt
    40861 cttcttggcg atggccttgg ccttcttcac cacgcccggg tccggctcat agcccttggg
    40921 gcagccgcag gagaggtcca ttccgaccat ggcgcagccg agcatgagcg agttgcagac
    40981 gttgttcccg tccccgacat aggccatctt gatgcccttc agcttgccca ggtgctcctt
    41041 caccgtcagc aggtcggcca tgatctggca ggggtgctcg aagttgtcca ggccgttgat
    41101 gaccggaacg gtcgcatgct tagccagctc catgaccatc tcatgctcgt acgcccggta
    41161 cataatcccg tcgacgtaac gggagagtac gcgggcggtg tcggccacgg tctctccgcg
    41221 gcccatctgc aggtccttgg tgttcagcgt aaccgcgaaa ccacctagct cgatcattcc
    41281 cacttcgaag gataccctgg tgcgggtgga ggacttctcg aatatcatgg ccaggacctt
    41341 gcccttcagc ggctggaagt ccatgtcccg cctcttcttc atatcctcgg ccgcatccaa
    41401 tatgtccagt atgtccacct ggacgtcgag catggtggtt aggtcccgct tcatctttta
    41461 caccgtcgtt aacattcacc cgaacgatga tattgatatc gccgggattc tgtaggattc
    41521 cgccgttgat aataaagggg atgattcgaa atcaacaaag ccgtggtttt atgtcccttg
    41581 acggtcgcgt gacccttttt ttaagatgga tgtccatcaa ggcagtatcc cgtagccgaa
    41641 gggcaggaac gagaacaaga agaagttcag taagccgtgc atgagagcga ccagtcctag
    41701 gctgctcgtt ctttgatagg cgtaggccag cgtcaatccc accaagaaca cgaatatcag
    41761 gtatggaatg ctacggtagc cagagtgcat gatggcgaac atcagggcag atacgaagac
    41821 ggccaggtac tttccgtaat gcttctctat cgaactttgc agcagcccgc ggaatatcag
    41881 ctcctccccg aatccgacga agacgaccat caccagtaac agcttgctga gggtgagggg
    41941 gcccagatcg tagacgagcg cctgattgtc caataggaag aattccaggt tggagcatag
    42001 atagccgaag ataatggcga tcagaaggta ctcccatttc caggtgacgt tcgaccggag
    42061 accgtgtccg ttcaggaact gcaccaggtt gcgccagtgc atcttttcaa cacccatcac
    42121 ggtctgcctc cagactatgt agccggcgat tatgatcggc ccgtagacga aaggcatcca
    42181 gagcagcgtt tccgtgaaga agaccggcat gccgatgttc agtacgcgca gcaaggacac
    42241 caaggcgaac gattggtaca tcagcatgcg cttatcgtcc catatgggaa gcagaatgca
    42301 ggcgaatatg ttcaatgcgt gcaacgccag gcaggactcc accgaaccgg tgaagtaaag
    42361 agcctcggct accgctataa tcaatatcgg cagcagaagt ccggcctttt cccgcatccg
    42421 cccttgattg agggcgcatg attaattact atcgtctggt gaatcgtaaa aaataaaaaa
    42481 aaggaggatt tgtcatcgta agcgcggatc taagcgcgca ggaaaaaaat gttgccgttg
    42541 actatgacaa agttcggctg gccctgggtc ttcttcattt ctttcacctc tttaatgatt
    42601 tcatatcggt ataatcgcat ttgaacgatg attgaaataa tatttaatca ttatcctgct
    42661 actacaacgt taaaaaatga ttttagtggt gtaaaatgac cgagataggc gtcgaacaga
    42721 tcaaggtact gtcggacccc aaccgtctgg ccatactatc gttgcttgcc ataagagaga
    42781 tgaccaccac tgccatatcg gatctgctgg ggctcagcgt tcagaacgcc cagtaccaca
    42841 taaagaagtt gctggaggcc gggctcatcg ttcccacccg taccgaactg gtcgggaacc
    42901 tggtagagaa atactatcgc tccgcgttcg aaccgggcat catgggcgac gcggccggag
    42961 taagttcggt ggacatcgct gaacggttga acatcgtctt cgcggccctc ggggccatca
    43021 aaggcatatt gaaccgcggg atacgcacca tggacgagag aaaggactat ttcatgaacg
    43081 tggacgaacg tccgaactat cctttcgggg cgaactacgt cgtgctgccg gtcagtgatt
    43141 ccgcggctca ggaggctgag aagctcattt ccgaccttga cgaccgccta aaggagctct
    43201 cggacaagca tccagaagag ggtaagccca agttcgccat cctctattcg gtgttcccgt
    43261 tcgagtgaga gggcgaatat ttattaagct tgacgcaatg ctgaaacccc atcatggccg
    43321 ggatggggta gcctggttat ccttggggac tgtggatccc cggacccgcg ttcaaatcgc
    43381 ggtctcggcc cctttttcat tccttcacca cttccagctc ccgttccagt atggccctct
    43441 ggcgctcggt cagtgttcgc gggtctaccg tgatgaccaa tatcgaacct tccacgatga
    43501 cctcgtccct cagctgggcc aagaaccgga gcaccttgtt gagatcgttg ttcagcatga
    43561 gatattccag cccttccatg gcgatcagcg aaggaccgtt gcgcaggaac tccaaggtca
    43621 tgtgggttag cagttgaagg ttggatgggt cgacccggtc cgggccgggg gtctgtgcca
    43681 accacagaat aggagtgtgc atcagctggt atctggctcg cagttggtcc gggtgcgtcc
    43741 gggtaattat gaatgcggac atcccgcccg acatctcctg gaccatcgat tcgaacatgc
    43801 gatcggagga agcgaactcg aataggtagg ctctgccctt caccagcgaa gggaccgggc
    43861 gatgaaggac cgtcggctcc acaacccgag gcggtaccaa gagctggtat cgcaatatgc
    43921 cataggccac cacagccact gagatgagct caccgaaccc atagatgcgg gggacctcgg
    43981 cgtcgaacac cgccaggccc atgatgacga tcattcccgc cgccggaatg gccaaagcgc
    44041 cgttgaagag tatggcctgt cttttctgga ccccgcgcag tgcgccccac ctgcgaacca
    44101 cggtgaccaa tagcaaggtc agatagacca acaacagcag tagcagcaac tggaagggaa
    44161 ggtggttgac cggcacccag ccatatttat catcgaccat cctcccgacc gagaacgccg
    44221 tggccaaggc caccgtcagc acgctgatct catacgccca tcggttcttg ccgaacagca
    44281 gcttggggac ggggtgaggt atcaaggtgc taagacgata cgccacgccc atctccacga
    44341 tcagcaggaa caccaacaac cggaacgccc agatggcctg ctcccccgta cctacgctgg
    44401 agaccaacag gtcgaggacg ctgcccgctc cggcgagaat ggtgagcagg aagaaggaac
    44461 ggttcaccgg agacgatcgc cccttcagca gaacgtagga cccgagaacg acctctgatg
    44521 tcgccagaag caggaacacc ggtgccaggg ggcttagctc gaccatggat ttggattatc
    44581 atgaatccta tggctattaa tgatgttcgc cgattatcac ggttgggaac caccctgggg
    44641 gtttcctata aatccgggaa gctgtatggg tttttagctt gaggtgaaaa ggatgagctg
    44701 gaacggtccg ctggaaaaga tcgatgacta tcgctggaag atccctcgct cctacaagga
    44761 gtgcatgaac ggggacgcgg tcatcttcgc ggacgagaag atgatcaaga ccatcatctc
    44821 cgacaactca ccagagcagg cggcgaacgt cgcttgccta cccggattgg tcgggaggtc
    44881 gatggccatg ccggacatcc actggggata cggtttcccc atcggaggcg tggcggccat
    44941 ggacgccgag gagggcgtga tctccccggg cggtatcggg ttcgacatca attgcggagt
    45001 tcggctcatc actaccaacc tgggcgtgaa ggacgtcacc ccaaagatca agcagctcat
    45061 aaacaccctg ttccagaacg ttcctgcggg agtgggctcc aagggcgtgg tggacgtcgc
    45121 ggcgaaccag atcgatcgca tactggaaga gggagcggag tgggcggtgg ccgaaggcta
    45181 cggctggtcc gaggacctgg tgcggacgga agagaacggc cgcatgaaga acgccgacgc
    45241 ttcgaaggta tcggcgaagg cgaagcagcg cggcgtgccc caggtcggtt cgctgggttc
    45301 cggcaaccac ttcttggaga tcgacaaggt ggataagatc ttcgaccccg tcgccgccaa
    45361 ggtcttcgga ctggaagagg ggcagataac cgtatccatc cattgcggct cccgcggttg
    45421 cggccaccag atagcaaccg attacctgca ggtcatggag aggtcggtca aggaccgcaa
    45481 catccgcctg cccgaccggc agttggcctg cgctcccgtg aactccaagg aaggacagga
    45541 ctatcacgcc gccatggcct gcggcgcgaa ctatgcctgg gccaaccgtc agatgatcat
    45601 gcactgggtg cgccaatcgt tcgagaaggt cttcgcccgc cccgccgagg atatggacat
    45661 gagcctggtc tacgacgtgg cgcacaacat cgccaaggtg gaggaccata cctatgaagg
    45721 gaagcgccgc aaggtttacg tgcaccgcaa gggcgccacc agggcgttcc cggcggaaca
    45781 tccggacgtc ccttccatct atcgctcggt cggtcagccg gtgctgatcc cgggggacat
    45841 gggggtcggt tcctacgtgc tggtcggcac cgagcgcgcc atgcaggagt ctttcgggtc
    45901 gacctgccac ggcgcgggaa ggataatgtc ccgcgaggcg gccatccgtt cctattccgt
    45961 gcaagcgata acccaggaga tggagaccaa gggcatctat ctgaagggga gcacccgtga
    46021 cggcattcag gaagaggcgc cgggagctta caaggacatc gacgatgtaa tacgagtggt
    46081 agtgggcgcc ggactgtccc ggccggtggc caagcttacg cccatcgggg tcatgaagg
//
LOCUS       DAOPZI010000007        44738 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_695_length_44738_cov_9.044514, whole genome shotgun sequence.
ACCESSION   DAOPZI010000007 DAOPZI010000000
VERSION     DAOPZI010000007.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 44738)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 44738)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44738
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_695_length_44738_cov_9.044514"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..760)
                     /locus_tag="PKM11_02640"
     CDS             complement(<1..760)
                     /locus_tag="PKM11_02640"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47443.1"
                     /translation="MAAKKTNENKPKESKKVKATEPERVQEVENPVLSKNPIRALMFK
                     DAMLQDIVDGLKAEQVPKEDMDEVLFLTAANAVLERIGMNLPEDLSSIFQENLDDYLS
                     IAMINKEHEVDLLSLFRDQFLESQGDDFNDERELMETLVAFEDQWWDSPKDFLGGAAP
                     NALMEEAREKMDAVIQHEGGCGCGCEEGGDENYWASRAYIIRDLWFASIEESMAKESM
                     PSPQKRERLFISVTNALLDLVVNVMPDFMTEDMFQ"
     gene            1043..1396
                     /locus_tag="PKM11_02645"
     CDS             1043..1396
                     /locus_tag="PKM11_02645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47444.1"
                     /translation="MALLMGLMLIFGGLILAMGILTSIPALGKYLEKLAKWLGRFQTI
                     IGVVLIILAIWWMLSGIGLTEIVALIAGLVLAMGILSSIPALGKSLEKVAKWLGRFQT
                     IIGVIAIIVGILAIL"
     gene            complement(1574..1680)
                     /locus_tag="PKM11_02650"
     tRNA            complement(join(1574..1634,1657..1680))
                     /locus_tag="PKM11_02650"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1620..1622),aa:Leu,seq:caa)
     gene            complement(1725..2654)
                     /gene="map"
                     /locus_tag="PKM11_02655"
     CDS             complement(1725..2654)
                     /gene="map"
                     /locus_tag="PKM11_02655"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II methionyl aminopeptidase"
                     /protein_id="HNX47445.1"
                     /translation="MGLFLKRRSKMYLLDEHGRDCIRKAGRLSSEARELGRSLVSEGV
                     RLRDVAESMELHILEHGGKLAFPVNISLNDMAAHFTPNSADEAVFRSGDLVKLDVGAH
                     VDGYLGDTATTVEVGTRNWQTLIQASERALQQALEVAQDGVSVGTIGGVVERSIKGAG
                     FRPVVNLSGHEMKRYNLHAGLSVPNYDDGTLTKLTGNMLLAIEPFATNGQGQVSNGRS
                     GNIYRVLRDRPLKEPEAEKLFQMIKQEFTTLPFCERWCDRLQPNSGATLRALHRHGVI
                     STYPVLGEIKQGMVSQAEHTILVGNGRGEITTA"
     gene            complement(2608..3249)
                     /locus_tag="PKM11_02660"
     CDS             complement(2608..3249)
                     /locus_tag="PKM11_02660"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HNX47446.1"
                     /translation="MDIIKSKGGKGTEIGLSKHDLEHILSTLRFGRLVVYPTETVYGL
                     GADPFDETAVKRVFLAKRRPFDMPLSIAVNDISVAEHIAELDENAYRLAKAFLPGPLT
                     LLVKKRPVLPDIVTASLPEVGIRIPDHPVALRMLEEFGPIVSTSANLHSHPNPVNVEG
                     AIADLGQSVATYVDGGPCKVGTPSTIVQIIDGTVEVIRYGAIPKEKIEDVLVR"
     gene            complement(3250..3891)
                     /locus_tag="PKM11_02665"
     CDS             complement(3250..3891)
                     /locus_tag="PKM11_02665"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47447.1"
                     /translation="MAVRCLAGMDFDSNVYLLTGEDPILVDAGTGMHHQDILKWLSSF
                     TKKGKVRRIVLTHRHYDHSGGASALAKELGAEVLMHPLDAPAVREGDPRQTLSYMFGV
                     HSQPVAVTELREGQVLTTGDSSYEVVHTPGHTSGGISLYNREGKVLLPGDTVFIGGVG
                     RWDLPSGNFEQLAGSVKKLLSLAPQELYPGHGDISQNGATGILEEALKYLGES"
     gene            4011..5138
                     /locus_tag="PKM11_02670"
     CDS             4011..5138
                     /locus_tag="PKM11_02670"
                     /inference="COORDINATES: protein motif:HMM:NF024938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HNX47448.1"
                     /translation="MNLLEHEAKGLFRRYRIATPRGLFYKDMNGIAGSLVNMKFPLMV
                     KAQTTRGGRGKAGGIRTALHDQEALEACERILGMHISGMRVHGVLLEEMIEASREIYL
                     AITIDQRSRCPLLLAGCAGGMDVENMPPHTMRRWTLDPLEPLSDEVLDQASHFLLHGD
                     PGTKEVRSTIGAMWRLFRNMDCELVEINPLMITDSGKAIAADAKVAIDDDSLFRHPEF
                     RDRYGRDLTELERLAKDKGFNLVELPGDIGVLANGAGLTMAALDTLQRYGGRGGTFLD
                     LGGTDDPDRISEALGLLSYDMARGRIRSLLVCIFGGITRCDTVADAMMHTITDRNVKA
                     RTVVRLRGNNEDEAAQMLRLANFNVQIDLDDACLQAVKVRT"
     gene            5135..6007
                     /gene="sucD"
                     /locus_tag="PKM11_02675"
     CDS             5135..6007
                     /gene="sucD"
                     /locus_tag="PKM11_02675"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: protein motif:HMM:NF004230.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HNX47449.1"
                     /translation="MTRNALLTNHKVLVQGITGKQGQNHTLQMLEYGTKIVGGVTPGK
                     GGRSVHGVPVFNDVQKAVERTGATASVVFVPADHLKQAAVEGMEAGLEAMVVITERTP
                     LHDAMQLLSMARKKGVTILGPNCPGLCLVGESKVGVMPNRIFRKGNLAVISRSGTLTY
                     EVVQALSSAGLGQSIVLGLGGDRLLGTDMREAVEMVLEKRPSGVIMIGEIGGQMEEEA
                     SLVIKEMGAENVFAYVAGVSAPPAKRMGHAGAIVSGRTGGAWDKIRALEGSGVAVGSS
                     LGDLVDLISRRSRT"
     gene            6421..9329
                     /locus_tag="PKM11_02680"
     rRNA            6421..9329
                     /locus_tag="PKM11_02680"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02540"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02540"
     gene            9798..11075
                     /gene="nifB"
                     /locus_tag="PKM11_02685"
     CDS             9798..11075
                     /gene="nifB"
                     /locus_tag="PKM11_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009399 - nitrogen fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogenase cofactor biosynthesis protein NifB"
                     /protein_id="HNX47450.1"
                     /translation="MSDIPLYVQEMLKSHPCYNEKAHKEFARMHLPIAPRCNIQCNYC
                     NRKYDCTNESRPGVTSEVLSPEEAVNKIRVVKEKIPQLSVIGIAGPGDPLANEETFTT
                     LELVKEEFPELTLCLSTNGLNLPRSVERLKALGVKFVTVTINAVDPEVGSKIYDFAIW
                     DGKLLRGKDAAEQLLKNQLEGIKMCTEAGILVKANIVMVPTVNADHIPDIAKKVKELG
                     AYIVNIIPLIPVPGTRFEHMPAPTPEQRKMLQDLCEGDIRQMRHCRFCRADAIGMLDN
                     DRSAEFAHITCGAREAPQGGPVGIQMEGTAKHRVAVATSDGKNVDQHFGQTKEFWLFD
                     VEDGKLKLVDKVRTDPFLEESMFGPKHHNKIERMVSALIGSDIVLTSGFGVKADAEIR
                     ARGMRPYKKDGPLDEAVLCAVRDLFEERAKVFE"
     gene            11080..12657
                     /locus_tag="PKM11_02690"
     CDS             11080..12657
                     /locus_tag="PKM11_02690"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: protein motif:HMM:NF006187.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HNX47451.1"
                     /translation="MKASRLLVECLKAEGVERVFGIPGEENMDVMDDIHQAGLEFVLT
                     RHEQAAAFMAATVGRLTGRPGVCLSTLGPGATNLVSGVADAYLSNLPMVALVAQAGAA
                     RVDPPQKQVLDLLAMFRPLTKRALDIGGPDDIPQSVRKAFDVASSERSGPVMLQLPED
                     VMRKEATGNPSPIPRKRAKRARELDIANVRNILSSSERPLVLAGHGALRENAVSALIK
                     FCESWNLPVGCTWMAAGAVPFDHELSLGTVGMRNSDLVKGSYEEADAVLLVGFDSTEF
                     QPQYWNRGRTKRIAYLGRSRPIPCRNMVLESTVLGSLTDSLGRLAADAIPRKSWHSVH
                     RQKLINDLTGKAEGPQALVQTMRRCMSRDDIMVSDVGAHLIWLAKYYPAYGPNTLLLQ
                     NGLIPMGIAIPSAIAAKMVHPERRVCATVGDGGFMMSSAELETAKRLGVNFVTVIFND
                     GGLGLIREKMTRSLGRSSNVELGNPDIPTFARSFGAEGYSVTGKEFETVFRDCLDRDA
                     LAVIDVRVDYSQNHHLF"
     gene            12700..13176
                     /gene="msrA"
                     /locus_tag="PKM11_02695"
     CDS             12700..13176
                     /gene="msrA"
                     /locus_tag="PKM11_02695"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HNX47452.1"
                     /translation="MTLKKATFAAGCFWGVEARFMKVKGVAQTEVGYMGGHTESPTYR
                     DVCTDRTGHAEVVQLTYDDSVVSYDGLLDVFWSSHDPTQRNRQGPDVGTQYRTAIFYH
                     DEEQRSVAERSKATLDASGRFKRPIATLVERAGPFWKAEEYHQKYLQKKGLDTCHI"
     gene            13246..15927
                     /gene="alaS"
                     /locus_tag="PKM11_02700"
     CDS             13246..15927
                     /gene="alaS"
                     /locus_tag="PKM11_02700"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR03683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HNX47453.1"
                     /translation="MTGSEFDLAFFQEKGFMRKQCPKCQRHFWSLGDWPTCGEPPCEE
                     YTFIGNSPMNRKLELHEMREAYLGFFEENGHGRVKRYPIVARWRDDVFFTQASIYDFQ
                     PWVLNGVIEPPYNPLTISQTCVRFNDIDNVGKTGRHFTFFEMCAHHAFNKKDGKFIYF
                     KDRTVELCHRFFTERLGTDPGKMRYIEEWWEGGGNAGPCVEVILDGVEVATLVFMMYR
                     DTPDGRKPMDMTVVDTGYGLERMTWVSQGVSSAYEAVFGPVVDWLKGLANVEPDKTVL
                     TEYSKVAGATNMKTAADVRRIRETTAERIGISYEELMKTISPLEDIYVICDHSRALML
                     MLNDGVVPSNVREGYFARMLVRRALRSIRSLNLDIRLSEAVGRQVDHFQDIFPELKEN
                     REDILNLVEVEEERYFETLGRGKQLVGRLVKDLKKGEKLSNEKLIELYDSHGLNPEIA
                     QEFAPGQIDVPDNFYMQVAARHEKPEADVAEAKERPEKMPETRMLYYEDPELVEFEGT
                     VIAEIDGGIVLDQSAFYPEGGGQEWDLGILDGKRVCRVIKIKTTIVHFVEGKNPAIGA
                     RVRGVIDLERRQQLMRHHTGAHLINGVARNLFGNHVWQAGAHKAVDQARLDVTHFENL
                     STEQRDTLEREVNRVVLQDRPISIQFMPRDEAEKLHGYRLYQGGAVPGKIIRVVEVQG
                     LDAEACGGLHCSHTGMVGPVRITRTKRIQDGIVRVEYTAGMAAVAGMQSDKRLVEELG
                     DSLNVPGEKLPETVTKLQDDLREQRKSIEHLSSVINDMSVKELVSEAPRAGEARVVVH
                     EALPGEDPEEMSKQLASMPCTVVVIGVPGERAKLLVACSSDVKMDCRKALKDIMAFMG
                     GGGGGKPDYAQGGGGDPARLRDALSKAYDVVSKEIGI"
     gene            16150..16653
                     /locus_tag="PKM11_02705"
     CDS             16150..16653
                     /locus_tag="PKM11_02705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HNX47454.1"
                     /translation="MAEAKKTTTPEEKDDFRYIVRIVNTDIDGNKPTVVGLQSIKGVG
                     KRVAEVIVRKAGVDRSVKIGSLDEAATTELTNLISTYADYAPNWAINRQADYETGEDH
                     HMVGVDLDMVLKDDINRLKMIRCYRGVRHDTGHKVRGQRTRSNGRKGLTLGVSKTRNQ
                     PAAKKEA"
     gene            16656..17339
                     /locus_tag="PKM11_02710"
     CDS             16656..17339
                     /locus_tag="PKM11_02710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HNX47455.1"
                     /translation="MGDPKFPRRSYDTPSHPWQGERIKEEAILVKQYGLKNKKELWKA
                     KTILRNLRKQSRDLQARLRIGEQQAKMETENLLRKCARIGLLPMEGTRLDDVLGLSDL
                     ALLDRRLQTVVFNRGLASTVGQARQFIVHGHVCIDDQKVTIPGYIVTREDEDKIIINP
                     RSPIANELHPLKQVQETASDRARRVEAEDAKKDLGKKKFVKHVPKEIEAAVQDVEDVP
                     NELPTEEVN"
     gene            17339..17722
                     /locus_tag="PKM11_02715"
     CDS             17339..17722
                     /locus_tag="PKM11_02715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020448644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HNX47456.1"
                     /translation="MGKWGIANVFASYNNIIITLTDVTGAETITKCTGGMVVKAAKDE
                     SSPYAAMRAAEKVAEIAKEKGIDGIHVKVRAPGGNRSTSPGPGAQAAIRALARAGLRI
                     GRIEDVTPVPHDGTKKKGGRRGRRV"
     gene            17734..18570
                     /locus_tag="PKM11_02720"
     CDS             17734..18570
                     /locus_tag="PKM11_02720"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: protein motif:HMM:NF001988.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit D"
                     /protein_id="HNX47457.1"
                     /translation="MHIKMLEEMETRAKFLVTDASPEKVNALRRALMMDVPKLAIDDV
                     EFHLGSSVDADGNEYESISPVFDEIVAHRLGLVPIPTDLDLFGFRDQCSCGGEGCPNC
                     TIYYSLEKRGPCEVYSGDLSCLGDSKFQVKDQLIPIVRLGERQGILAYAIAELGTGRK
                     HAKWQPTHGVGYKYFPTVTIDQSKCDNGGTCIKVCPKAVMNFKDKKVQVLDNDACVLC
                     EECVKVCRTGAIKVKWSDNKFLFEFETDGSLSARVALSKALESLEKGFDEFREKVASL
                     EG"
     gene            complement(18610..22044)
                     /locus_tag="PKM11_02725"
     CDS             complement(18610..22044)
                     /locus_tag="PKM11_02725"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II large subunit"
                     /protein_id="HNX47458.1"
                     /translation="MQELACSESMRRYFSGLFQENERCYALATEARAKGLDPSTMVEI
                     PQAEDLAARVEKQLADWHVEGVAERIRELAKRIESREELSLFIAKELAMEAVAANEGR
                     EMAMDRAVRVGLSVLTEGILVAPIVGIAGVKINANPDGTEYISVFFNGPIRAAGGTAQ
                     AMSVLIADVVRREFGIGTYKPTVGEVERLKEEIPLYKQIQHLQFTPSNQEIEIIYRNC
                     PVCVDGEKTEDAEISGYRNLPRIKTNAVRGGVCLVIAEGLCLKAPKIEKHVKKLGLEG
                     WDFISEYLKLKKGAATEQKEVKVVPDYKYLKDIVAGRPVIGHPSRPGGLRLRYGRART
                     TGLAAIALSPATMFALDDFLAIGTQIKIERPGKAGAVTPCDRLEGPILLLDNGDLVQT
                     NTVAEFKAVKERMKEIVDVGEILFPFGEFVENNHVLVPGDYDLEWHRAELYAANDWQL
                     PDGWEDPQDFATALDMSKRYNVPLHPKYNLFWYDLSLEALQGLRVSILSQGKFAGGSL
                     RVPLEPGSKRTLETLGALHQVVDGDVIIERYSEPLLAGLGLLGEGRVEDRVPLEGATV
                     MEAVSRCTGVKVNPRAVTRIGSRMARPEKAKDRSAKAPSHTIFPIGMHGGPQRLMEKA
                     AGKGNITVKLGVRKCQLCGEHRVYYRCPCGGHTLPVGDSKDVPVNLAEELEKARKALG
                     ERSILPKLKGEKELKSKDMCPEPLEKGILRRKHEIYVNKDGTIRFDLTDVPLTHFRPR
                     EIGLSVQKALELGYDHDIYDQPLTDPEQLCELKVQDIVPSNSCGDFMVRVADFIDDLL
                     ERFYELPRHYNARSKEDIIGHLAIGLAPHTSGGILCRIIGFTKASVCFGHPFFHAAKR
                     RNADGDEDSVVLLLDGLLNFSRSYLPDSRGGLMDAPLVLALRLDPNEVDKEAQNIDVH
                     WEYPLEFYRACVDYRHPKDIQSKMDLVADRIKSLLQYEGFGFTHDTYDIAEGPDESAY
                     KTLETMMDKMTAQLELAKRIRAVDEGDVVHRVITKHFLPDLIGNLKSFSGQKFRCTKC
                     AESYRRVPLSGHCYCGNKLNLTVYEASVKKYLEVTSRIGRDYGVSEYTQQRIRLIEKS
                     ITSIFGEEISSTPLDSYDEGGEEQSLELHSDPDADDPVEEGPSGSEGKRTICLDDF"
     gene            complement(22090..23076)
                     /locus_tag="PKM11_02730"
     CDS             complement(22090..23076)
                     /locus_tag="PKM11_02730"
                     /inference="COORDINATES: protein motif:HMM:NF014474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HNX47459.1"
                     /translation="MQNLRKRVPTILTSDEILDKAFRKVNKIDKQGPDKVELVKRKSM
                     ARIASATDVISSTLMKYVKAFPSINERTDFLAEMIEVTVGVDKMKKALGNLDWAASKI
                     KELQKQYTSKVMTSTSTFAADNARKAYYGRASSVVNKVGPDLEFLAYARNEFRKVPDF
                     NDDMLTFVIAGFPNVGKSQFLRTISAAEPEVAAYPFTTKGIEVGIHEANHRRYQVIDT
                     PGLLDRELEYRNRIEMQAVTALKHLANSILFILDPSESCGYLMEGQLRLLESVKALFP
                     DVPILVVENKVDMIDSGSDRLKMSAATGVGVQEVMAALRESVKHLETVEPAF"
     gene            23110..23811
                     /locus_tag="PKM11_02735"
     CDS             23110..23811
                     /locus_tag="PKM11_02735"
                     /inference="COORDINATES: protein motif:HMM:NF012514.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HNX47460.1"
                     /translation="MAPAMTYSLRADPVLVKDERDLLDGDDLHLLVLLRDVGTDGAAA
                     TLGNTKGTVLRKVRRIERKVGGKILENGTLNRYGNELVERMELYVRLLEAQLEILWRN
                     PSLTCDGLLLREGKVLLVKRGREPFQGRHALPGGFVEYGESTEDCVVREIREETGLDT
                     EVERLVGVYSEMGRDPRGHFVTLLYLLRETGGDLQAGDDAASAGFFKLSDLPELAFDH
                     GKMIRDGLRSAEHPL"
     gene            23836..24279
                     /locus_tag="PKM11_02740"
     CDS             23836..24279
                     /locus_tag="PKM11_02740"
                     /inference="COORDINATES: protein motif:HMM:NF013224.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HNX47461.1"
                     /translation="MGQDDLDETILRMLQGNGKLSIEELAEKLGRSPSTIRDRMRRME
                     EERLILGYSVIVDQERLDIDAEALVLADIDPQMEGKAMSALMSMEEVGEVMKVTGEPR
                     LMFRVRASDRQELLGFLDRKIRPLGFRRLDVRLILDRPVRYPGSV"
     gene            24320..25594
                     /locus_tag="PKM11_02745"
     CDS             24320..25594
                     /locus_tag="PKM11_02745"
                     /inference="COORDINATES: protein motif:HMM:NF014135.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HNX47462.1"
                     /translation="MQTVTWLALLVFLFTYTLISVRRVRSVSIDRPAAALFGAVLMVL
                     LGVVTADQVLEAIDLDIIGLLLGMMIIVSCLEITGLFDRVAVILVNRCADRFTLLWLS
                     MGVTALLSALILNDTVVLMFTPILIKVCRSIDANPVPYLVGEALAANIGSVATGVGNP
                     QNAYILIQSGITFSDFALALAPLALISLAVAVGMVALVFRKEIFDGGLGKPRPIDRSL
                     VMAAAPRKRMEAPFFLVLAVLVAVFIGFTASSWLGIPISLVAFLGGCFLLLALPLMKK
                     DTGTSPILRGVDWTLILFFVGLFILLKGVETSGLMDMMLSSFEDMGAGMAGVAGLTVI
                     SSVLSNLISNVPAVMLLSPVVPAGNQTLWLSLAASSTLAGNATILGAAANVIVLEKGL
                     SMGVEVRLWDFVKAGLPVTLVTLLISVLFLGI"
     gene            complement(25633..26271)
                     /locus_tag="PKM11_02750"
     CDS             complement(25633..26271)
                     /locus_tag="PKM11_02750"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: protein motif:HMM:NF009668.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA];
                     GO_process: GO:0098869 - cellular oxidant detoxification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HNX47463.1"
                     /translation="MPLIGDKFPDMTVTTTHGPMSLPKDVAGKWLVLFSHPADFTPTC
                     TTEFVAFAKKAEEFKKMDTVLVGLSIDQVFSHIKWVEWIEENLGVKIPFPIIADHGDV
                     AMRLGMIHPGKASNTVRAVFIIDPKAIVRLIIYYPQEIGRSVNEVVRALQALQFCDKN
                     GLATPEGWPNSELVGDRAIIPPPKDYKTAMERKKNVGKGKDCYDWWFCTKKI"
     gene            26487..26939
                     /locus_tag="PKM11_02755"
     CDS             26487..26939
                     /locus_tag="PKM11_02755"
                     /inference="COORDINATES: protein motif:HMM:NF014062.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HNX47464.1"
                     /translation="MSLATDLSLVFIVIGVLMLLVEISQPGSFLLVPATVLLALGGVG
                     LVFPDLLLTVWSPIIAVVILVPTTFLTIKMYQRLAPPAPPQTTVATSLIGKEGSVETE
                     VVPGSLRGKVKIANVMWSATSAMPIPVGKRVKVVRSEGVHVTVEEIIQ"
     gene            26957..28060
                     /locus_tag="PKM11_02760"
     CDS             26957..28060
                     /locus_tag="PKM11_02760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HNX47465.1"
                     /translation="MAIGVEIFGLLILAIIAAIVIVVNGVKIVRPYEQAVYIRLGMFI
                     RILNPGFNYVAPLINETVKLDLRTQVLDVPRQEVITKDNSPVNVDAIIYVKVIDPKKA
                     FFEVTDYRAATVYLAQTTLRSIIGDMELDEILSNREKINLKLRDILDEATDQWGVKVD
                     AVEIREIDPAPKVKQAMEEQTSAERLRRAAILKADGAKTAAILNAEGEKRSRVLQAEG
                     LRQAKILEAEGERLAIILESQGEAQKLRILSVGASTLDTKALTVLSLDALKKLGEGQA
                     TKIVLPFELTRLVEGISDYVGGVRSIPEREISKPEEIERTVGKADIILGPIPTQEELR
                     RDMKELEVAMAQERREAEAIKAGTRVSLEKDRE"
     gene            complement(28159..29814)
                     /locus_tag="PKM11_02765"
     CDS             complement(28159..29814)
                     /locus_tag="PKM11_02765"
                     /inference="COORDINATES: protein motif:HMM:NF016289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family peptidase"
                     /protein_id="HNX47466.1"
                     /translation="MRCKFTALLIALLVMVPSLLVIPGAMAAGVDTSDADRLMDQSWN
                     GDNIISLTEELSNISSNYLAYRVSGSPGANEAADFIAEQFTSYGLQVTMDNFTMPVWN
                     LADEPSLTINMDGNVTTSDGIRLGSFNCESFSKPTSSNGLVGELVTLPLPPASNYGEV
                     GKKSIDRQAWSNINITGKVLLIGREVRWSSGWEGVYKNKLLSQPPAAIIYDYNYPWMS
                     YAQQNSQSSSGGLPLGEMGPIFWNLNIPVGSVNYSDGQLLVQTALHGGSVNMSVPTVI
                     SQGTHKNVIADVNGGSSSTKLVLFGAHYDTVLSEGYVDNSGGVAAILETARVVQEAVD
                     AGDLDLKYRMRFVAFAGEEMGLAGSLHYVSMHRGEMGNQVASIIADSIGSSDLKVTLA
                     GSDGEVDLNFVADEACSRLGVAHSFQDLAGSDHYSFMFPYWMSNELNRAWGKDLGIGR
                     GLESTSTMCVYSQPLTIYDDVGGEANGHIHTSLDSRAAVKNGEWVDEQDLRDQAQVYA
                     LMALYAGIGIFEPNYDYLPYVIGLVAVTLIIAFFMLRRWKIKF"
     gene            complement(29901..29974)
                     /locus_tag="PKM11_02770"
     tRNA            complement(29901..29974)
                     /locus_tag="PKM11_02770"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29938..29940),aa:Ala,seq:tgc)
     gene            complement(30018..31664)
                     /gene="ilvD"
                     /locus_tag="PKM11_02775"
     CDS             complement(30018..31664)
                     /gene="ilvD"
                     /locus_tag="PKM11_02775"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HNX47467.1"
                     /translation="MRSDAVKKGVDRAPQRSLLRATGLTDADMEKPLIGIANSWNDVV
                     PGHIHLNELAEEVRKGIIEAGGVPLTFGVPGVCDGVAMGHAGMRYSLVSRDVIADCVE
                     IMVQAHCMDAWVGVTNCDKITPGMLMAAGRLDIPTIILTGGPMEPGHKGDKGLDLQSV
                     FEALGANKAGKMSEAEVLEIERCACPGQGACSGLFTANTMACLTEALGLSLTGCGSML
                     ATDPRKKELARATGRRIVEMVKENLTARKVVRKGSFTNAIILDMAIGGSSNTALHVPA
                     IAQDFGVGVDLRTFDEISKRVPHLTSIKPSGPYYMKDFDAAGGVPAMLNRLRSELSDE
                     MTVNGVSIKDIARRAIVHDQEVIRPMDRPFHAEGGIAVLYGNLAPLGSVVKQAAVSPE
                     MMHFEGTAKVFDSEQEAYEAISARKIVAGDVVVIRYEGPKGGPGMPEMLSPTSLIAGM
                     GLSNSVALITDGRFSGATRGPCIGHVSPEAFDKGPIAAIHNGDRISIDIPGRRIELLV
                     PQKEIEERLAKVVVVDRKPTGVLAKYRRLVGVASTGAICR"
     gene            complement(31706..32575)
                     /locus_tag="PKM11_02780"
     CDS             complement(31706..32575)
                     /locus_tag="PKM11_02780"
                     /inference="COORDINATES: protein motif:HMM:NF013117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HNX47468.1"
                     /translation="MAEPTLLGLSVTDLIGFIIVVLVTIALAKGTNMLARRFLDSRIS
                     RTESKAVARLLQYSVLALGLYLGFWEVLGLDMTALLASLGILGLGVALASQQVLMNAF
                     SGILMSFTKPVKIDEWVEISGVPATGIGKVKDINLMNTVLKDLDGRILYVPNSVMVNN
                     KVINYSRAGIVAIRIPLWLRSLKDFERIKDLILDVADKDPLILPHVGAEEQKKVNKTF
                     ELSSVRRYLEKKTDMSLFAPSISIKDIQREKVKVEIMIWIRDVSKRDEIVTSYLDALR
                     LRFAEEGIEFGDD"
     gene            complement(32716..33027)
                     /gene="rpsJ"
                     /locus_tag="PKM11_02785"
     CDS             complement(32716..33027)
                     /gene="rpsJ"
                     /locus_tag="PKM11_02785"
                     /inference="COORDINATES: protein motif:HMM:TIGR01046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HNX47469.1"
                     /translation="MAQRARISLSGTDPEKVDSVCTQIKQISTRTGVAIRGPIPLPTK
                     RLQVPCRKSPDGEGSETWDRWEMRIHKRLIDLDADERALRQLMRIQVPDGVNIEIVLR
                     S"
     gene            complement(33064..34341)
                     /gene="tuf"
                     /locus_tag="PKM11_02790"
     CDS             complement(33064..34341)
                     /gene="tuf"
                     /locus_tag="PKM11_02790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor EF-1 subunit
                     alpha"
                     /protein_id="HNX47470.1"
                     /translation="MADKPHMNLVFIGHVDHGKSTTVGRVLLESGAIDPYVIEKFKKQ
                     AEEKGKATFEFAWVMDSLKEERERGVTIDVSHKRFDTDKYYFTVIDAPGHRDFVKNMI
                     TGTSQADAAVVVCSAIEGPQAQTREHVFLAKTLGVKQIIIAVNKMDAVKPAYDEAQFN
                     KVKEQMGVLLKSVGFKLEEIPIVPISAYKADNIKVKSANTAWYKGPTLFECLNNLKVP
                     ASTEGLALRLPIQDVYTITGIGTVPVGRIETGVLKPDMKIIFMPSNKVGEVKSIEMHH
                     EILPIARPGDNVGFNVRGIAKNDVHRGDVAGPVDNPPTVAKTFTAQIVVLNHPTAIPV
                     GYTPVFHCHTAQVACTFIELMKKLDPKTGQVKEENPHFLKTGDIAIVKVMPTKPFVVE
                     KAKDFPQLGRFAIRDMGQTVAAGICIDVEKKEM"
     gene            complement(34426..36624)
                     /locus_tag="PKM11_02795"
     CDS             complement(34426..36624)
                     /locus_tag="PKM11_02795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor EF-2"
                     /protein_id="HNX47471.1"
                     /translation="MGRKEDNIKKAQDIMMTPEFIRNIGTAAHIDHGKTTLSDNLIAG
                     AGMMSENLAGKQLMLDFDEQEQARGITINAANASMVHTYHGKDYLINLIDTPGHVDFG
                     GDVTRAMRALDGCIVLVCAVEGIMPQTETVIRQALKERVRPVLFINKVDRLVNELKVT
                     EQEMQQRFIQIIAEVNKRINANLPEDLRKKWQVKVEDGSVAFGSAYNNWAISAPYMKK
                     SGISFKDVYNYCKNEDQKTLAKKSPVHEVLLDMVITHVPNPFEAQKIRIPIIWKGDQQ
                     SEVGKAMMHCDRQGPTTFMCTKIIIDPHAGEVAVGRMFSGKIVRGQEMYILGMPNPNR
                     VQTVSMSVGADRIAVDEVEAGNIVALSGLKDAIAGATCSSDKDMEPFEKISHYTEPVV
                     TVAIEAKHMKDLPKLVEVLRSVGKADPSIQITINQETGENLLAGMGELHLEITQYRIV
                     NDHKVDIKSSAPIVVYREAVRARGGPFEGKSPNKHNKFYMIVEPLEQAIVDAIKSGEI
                     RTEGKIKDPKALAKQLSDLGLDKDQAKGVVCFKNNNVFIDTTKGIQNLHETMELCKQA
                     FEEAMEQGPLANERVAGLKVMLVDAKLHEDSIHRGPGQVIPATRSGIYGAMCLAGRSL
                     LEPMQKVYINCPQDMMGDVTRELQGRRTTIEDIHQDHDATVIISKAPVAEMFGFASAI
                     RGATQGRALWSTENSGFVILPRELQDKVVGEIRKRKGLNPQPYDAGYYSG"
     gene            complement(36639..37226)
                     /locus_tag="PKM11_02800"
     CDS             complement(36639..37226)
                     /locus_tag="PKM11_02800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020449313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HNX47472.1"
                     /translation="MEESSFKFDNIMLFGKYASGEVVVKDGGLAKYINLTPTAVPHTT
                     ARHANKWFGKSKVNIVERLINNMMRTEVYTGKKLKAYNVTKKAFEIIEQRTKKNPIQV
                     LVEALENAAPREEITRLQFGGISVPKAVDVAPSRRLDIALRNISKGSVNASFKNTKPI
                     EQCLAEELILASKGDMNSFSVAKKEEIERVASSAR"
     gene            complement(37232..37660)
                     /locus_tag="PKM11_02805"
     CDS             complement(37232..37660)
                     /locus_tag="PKM11_02805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018039449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HNX47473.1"
                     /translation="MAKGLFTARKLRNDRQKSRWSDRSYKRRLLKLRERSDPLEGAAQ
                     AKGIVLEKVGIEAKQPNSAIRKCVKVQLIKNGRQITAFAVGDGAINFIDEHDEVLVEG
                     IGGRMGRSYGDIPGVRFKVIQVNNVSLNELVRGRKEKPVR"
     gene            complement(37792..38205)
                     /locus_tag="PKM11_02810"
     CDS             complement(37792..38205)
                     /locus_tag="PKM11_02810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47474.1"
                     /translation="MSDDLVFKVAKRRLQEIQEELPHPDIATHFSIDEVGRGSIDIFY
                     QGALIGHEIIETADSWKDEGRLIAYRDVLRKKIRLVVMAPRSEAMQVRYRMLELNNWW
                     LFYYMVYGYDGAGRLVRVLRPHPPDRKTPETSYIS"
     gene            complement(38250..38822)
                     /locus_tag="PKM11_02815"
     CDS             complement(38250..38822)
                     /locus_tag="PKM11_02815"
                     /inference="COORDINATES: protein motif:HMM:NF014056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF99 family protein"
                     /protein_id="HNX47475.1"
                     /translation="MKDQARVLGIDDGPFEKGQARAQLAGVLVRPPGYVEGVMISSCQ
                     VDGDDANEAISSMVKDSRFSEQVRMVMVDGAALGGFNVVDVRALSEEIGVPVLTISRD
                     EPNLTEIIDALRAHFPDWERRFEVISRNRVRPLEVPDGRVYVTSEGIGEKEADAMVRQ
                     CIVRGCLPEPVRLAHLIATALVRGESRGRA"
     gene            complement(38823..39197)
                     /gene="pth2"
                     /locus_tag="PKM11_02820"
     CDS             complement(38823..39197)
                     /gene="pth2"
                     /locus_tag="PKM11_02820"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase Pth2"
                     /protein_id="HNX47476.1"
                     /translation="MCEPYMDFELKMVIVVRKDLKISPGKMAAQVAHAAVNCAFASKK
                     RKPINFDRWYNEGQKKVVVKVQDLAELYKIKQAAEDLGLVTSLITDAGMTELPPNTTT
                     CLGIGPAPNAEVDRVTGHLGLM"
     gene            complement(39190..39408)
                     /locus_tag="PKM11_02825"
     CDS             complement(39190..39408)
                     /locus_tag="PKM11_02825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47477.1"
                     /translation="MESFVMCCPKCEILITVLVQDCIDGREFPCPICGKTIIIKFTAE
                     EAEKKIELAEKNQERVLRRQFPLAFGDV"
     gene            39503..41449
                     /gene="tgtA"
                     /locus_tag="PKM11_02830"
     CDS             39503..41449
                     /gene="tgtA"
                     /locus_tag="PKM11_02830"
                     /EC_number="2.4.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(15) transglycosylase TgtA"
                     /protein_id="HNX47478.1"
                     /translation="MLELVKRDGLARICRLHTRQGELETPCLLPVINPRLITISPREL
                     YDVFGFRALITNSYIIRSDPKIREDALSKGLHELLDFPGVIMTDSGTFQSHMYGEVDL
                     INKEIVEFQRDIGSDIGTVLDIFAEPDWSKERTAQSIEVTLERTMEAAELKGEMLLAG
                     VVQGSIYPDLREMCARRLSEMGVDVNPVGGVVPLMETYRFAELVDVIIAAKKGLRPDR
                     PVHLFGAGHPMLFALAVLLGCDMFDSASYAKFARDDRFMFLEGTFRLADMKALECNCP
                     ACHGHDLEEIKALPPAKRTALIARHNLWVSKMELERVKRAIMEGDLWELVERRCRSHP
                     ALLDALRALGKHQEFLERYEPLSREHALFYTGPETLNRPAFLRFHKRSTERYEHPATE
                     VGMVFEEPEKPYSRTLRSAMDSILEISDAHFHVISPFGPVPIELDEIYPISQSLFPKN
                     QDQQTVERTKELMEELGHTHSYKMGAIWDGDETLEFLKMFSQGKGTFDIDMARVRAVA
                     DYQFGKGAADALLSGNVSLVKSKNVDRIRNVLVDGEHVFSMRAEDGFLTLRPAGARRL
                     LKGIPAPRMRVTIQDDAVEFNKQGKNVFCSFVTDADPEIRLHDEVMVVDKDDNLVAIG
                     RAQLTREEMLCFKKGVAVKVREGA"
     gene            complement(41446..41673)
                     /locus_tag="PKM11_02835"
     CDS             complement(41446..41673)
                     /locus_tag="PKM11_02835"
                     /inference="COORDINATES: protein motif:HMM:NF011470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex subunit Pcc1"
                     /protein_id="HNX47479.1"
                     /translation="MEASCLLELDLGSEERARNVNRSLELDNGDHARSWVEGSVLKVE
                     CQAKGLMSLLHTIEDLMACLKVAEEITDVED"
     gene            complement(41731..41806)
                     /locus_tag="PKM11_02840"
     tRNA            complement(41731..41806)
                     /locus_tag="PKM11_02840"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(41770..41772),aa:Gln,seq:ttg)
     gene            42072..43010
                     /locus_tag="PKM11_02845"
     CDS             42072..43010
                     /locus_tag="PKM11_02845"
                     /inference="COORDINATES: protein motif:HMM:TIGR00367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0098662 - inorganic cation transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HNX47480.1"
                     /translation="MLLDILYLLGGLVLLIIGADRLVKGASALAASLGVSTFIIGLTV
                     VAMGTSAPEATLAVISSLEGDPSISFGNVIGANIVNIGVVLATACMICPIASEMTLLR
                     REAVFLIISILAVAILGYNGVIDLSSALVLIAAAVAFNLFVLRSAKGEKAAKRIEPVE
                     ERPTMEKWRMLVFIVGGLALLIFGSELVMRGGVGLATDLGVDEFTIGLTIVAIGTTMP
                     EMAVSISSACRLETNMLLGNVLGSNIFNSLLIIGLAGLFSPIAVPGDFYTLALPVTLV
                     MYAALVSFMFMKRKLNRTTGAILMAIYIGYLALLLI"
     gene            complement(43055..43339)
                     /locus_tag="PKM11_02850"
     CDS             complement(43055..43339)
                     /locus_tag="PKM11_02850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47481.1"
                     /translation="MLITLTVKNEAQGGHIHLAKVDMDGEKEIGSLHYENEEDKVWLL
                     KVLMDGHPNVSLMGANEKAAGAPEGEYKPCCFFGAMIDAMYEAEQKKNTS"
     gene            complement(43344..43601)
                     /locus_tag="PKM11_02855"
     CDS             complement(43344..43601)
                     /locus_tag="PKM11_02855"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47482.1"
                     /translation="MALYINMKVLENEDGSGTLELWKRGSITCTHILGTLKYENKDER
                     DVLLDMLMKGHPEISFMEKDNPTGCFVDNYYKWPQRGPITR"
     gene            complement(43816..>44738)
                     /locus_tag="PKM11_02860"
     CDS             complement(43816..>44738)
                     /locus_tag="PKM11_02860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47483.1"
                     /translation="IALHEAKIISTTNPEKMTEADISAYILWMRSKGQEGSYMAKNLG
                     FLKQVCDFAGNPVFARIKTSGEELPKKTPKDLHSLSEGELKLILGKADLLKGWEGEVC
                     RFLMYMYPYTGLRASELRLSHLEDLNTHDWSIYVRHPKGEDRYARKRTAPVLPPARKA
                     VFRFLNAREQRLKRLGITECDALIPARHSDGTAGFYCSNAFRNMKKGFMEGINMDLEG
                     SRIEFQLKTMRDTFVQMNIDKDPSKTAAVSMAAGHSTTKTTETTYGRIKNGQALMTLN
                     KLWEDDVSSSYPLKDKNPLIESKFDMTGYQ"
BASE COUNT         9502 a        12481 c        13036 g         9719 t
ORIGIN      
        1 cctggaacat gtcctcggtc atgaagtcgg gcatgacgtt cacgaccagg tccagcaatg
       61 cgttggtcac ggaaatgaac agccgctccc gcttctgcgg ggacggcatg gactccttgg
      121 ccatgctctc ctcgatgctg gcgaaccata ggtctcttat gatgtaggcg cgtgaggccc
      181 agtaattctc atccccgccc tcctcgcacc cgcatccaca tcccccctcg tgctggatga
      241 cggcatccat cttctcccgt gcctcttcca ttagcgcgtt cggcgcagcc ccgcccaaga
      301 agtccttggg ggagtcccac cactggtcct cgaaggcgac gagggtctcc atgagctcgc
      361 gttcgtcgtt gaagtcgtcc ccctgagatt ccaggaactg gtcccggaac agggacagca
      421 ggtcaacctc atgctccttg ttgatcatgg cgatggacag gtaatcgtca aggttctcct
      481 ggaagatgga agaaaggtcc tctggaaggt tcatgccaat gcgctccaga acggcgttgg
      541 ctgccgtcag gaaaagcacc tcgtccatat cctccttggg cacctgctcg gccttcagac
      601 cgtccacaat gtcctggagc atggcgtcct tgaacatcaa ggcccggata gggttctttg
      661 acagcaccgg gttctccacc tcttgtaccc tctctggttc tgtcgctttg actttctttg
      721 actccttagg tttattttca ttggtcttct tggctgccat gatcgcacct tccagatgac
      781 gccttgtcac atatacaagg catttattgg tatgaacgga caaagcccga tggagatata
      841 aatccatggc gttggaccgg accgatgccc aggcccggtt tcttttagac tggaacagtg
      901 cgatcagatc ggactatatg atcagtcgta accattgttg acctaagaat taattggtta
      961 atacatccag tatgaaataa tattgaataa ttatttatac gaacattggg gatttactat
     1021 gaaactattt ggaggttaaa aaatggcatt actaatgggg ttaatgttga tattcggggg
     1081 tttgatcttg gccatgggta tcctaaccag catccccgct ttgggcaagt acctagagaa
     1141 actggccaag tggctgggca ggttccagac tattatcgga gtggttctga taattttggc
     1201 gatctggtgg atgctcagcg gaattggcct gaccgagatc gtcgccttga tcgcaggcct
     1261 ggtcctggcc atgggaattc tctcgagcat tcccgccctg ggcaagagcc tggaaaaggt
     1321 cgccaagtgg ctgggcaggt tccagacgat cataggcgtc atcgccatca tcgtcggtat
     1381 cctggccata ctctaaacca atagggcctt cgggcccaaa ttaatttttt cttattttca
     1441 tattattaga tgccgtatct actggagatc tggcacctca acaccgtttg tttttaagaa
     1501 tgacaaaaaa ccctcactgc tctataaaca gctatgtctg gaagggagaa catcttcaga
     1561 gaatagagaa tagtgcgagg gaccggattc gaaccggcga acctctgcag gaacagatct
     1621 tgagtctgtc gcctttggtc ggcgttccgc acgccattga ccgagcttgg ctaccctcgc
     1681 gtgaggccag ataaaagagc cgaccttaat aaatgtattc gagctcaggc ggtggtgatc
     1741 tcgccacggc cattccccac cagtatggtg tgctcggcct gggagaccat gccctgcttg
     1801 atctcgccca gaacaggata ggtagagatg accccgtggc ggtgaagtgc tctcagcgtc
     1861 gcccctgaat taggctgcag gcggtcgcac caacgctcgc agaacggcag cgtcgtgaac
     1921 tcctgcttga tcatctggaa caacttttcg gcctccggct ctttcagagg acggtccctc
     1981 aagacccggt aaatgttccc tgaacggcca ttcgatacct gtccctgacc gttggtggcg
     2041 aacggttcta tggccaggag catattgccc gtaagcttgg tcagtgtgcc gtcgtcataa
     2101 ttgggaacgg aaagaccggc gtgcaggttg tacctcttca tctcatgacc gctgaggttc
     2161 accactggac ggaacccggc acccttgatg ctcctctcga ccaccccgcc tatggtgccc
     2221 acggagaccc cgtcctgagc cacctccaac gcctgctgca aggccctctc tgaagcctgt
     2281 atgagagttt gccagttacg ggtgcctacc tctacggtcg tagctgtgtc gcccagataa
     2341 ccgtcgacat gcgcccccac gtccagtttc accaggtcac cggatctgaa gaccgcttcg
     2401 tcagcgctgt ttggagtgaa gtgcgcggcc atatcgttca gggatatgtt taccgggaag
     2461 gccaatttgc cgccgtgctc cagtatgtgc aattccatgc tttcggcgac gtcccgaagc
     2521 cttacgccct cggatacgag cgatctgccc agctcccggg cctcggagga taggcgcccg
     2581 gctttgcgaa tgcaatcgcg gccgtgctca tctaacaagt acatcttcga tcttctcttt
     2641 aggaatagcc ccataacgga tcacctctac ggtcccatcg attatctgga cgatggtcga
     2701 aggggtgccc actttgcacg ggccgccgtc cacgtaggtg gccacgctct gacccaggtc
     2761 agcgatggcc ccctccacgt tcaccgggtt ggggtgtgaa tgcaaattag cgctcgtgga
     2821 tacgatcggc ccgaactcct ccagcatgcg cagggccacc ggatgatctg gaattcgtat
     2881 ccccacctcg ggcagggaag cggtgactat gtcgggtagc accgggcgct tcttaaccaa
     2941 cagagtgaga ggaccgggaa ggaaggcctt ggccagccga taggcgttct catcaagctc
     3001 ggcgatgtgc tcggcgacgc tgatatcgtt aacggcgatg gaaagcggca tgtcgaacgg
     3061 ccgcctcttg gccaggaaca ctctcttcac cgccgtctca tcaaatggat cggcccccag
     3121 accgtacacg gtctcggtgg ggtataccac caacctgccg aaacgcaggg tggacagtat
     3181 gtgttccaga tcatgcttgg acaggccgat ctcggtgccc tttcctccct tgctcttaat
     3241 aatgtccatt caagattctc ccagatattt taacgcctct tccaatatcc ccgtggcccc
     3301 gttctgactt atgtcgccgt gacctggata taactcctgg ggagctaggg ataaaagctt
     3361 tttgaccgaa ccagcgagct gctcgaagtt accgctcggc aggtcccagc gacctacccc
     3421 tcctatgaac accgtgtccc cgggcaaaag cacctttccc tcccggttgt atagcgatat
     3481 ccctcccgag gtgtgtccag gcgtatgaac gacctcgtag ctcgagtccc cggtggtcag
     3541 gacctggccc tctctgagct cggtgaccgc cacaggctga ctgtgtaccc cgaacatata
     3601 ggacagggtc tggcgagggt ctccctctct tacggccggg gcgtccaagg ggtgcattaa
     3661 aacctcggct cccagctcct ttgccagtgc tgacgccccg ccgctgtgat cataatgacg
     3721 atgcgtcagc actatgcggc gcactttgcc ttttttagtg aaggatgaca accatttgag
     3781 gatgtcctga tgatgcatgc cggtaccggc atcgacgagg atggggtcct caccggtcag
     3841 aaggtacacg ttggaatcaa agtccatacc agcgagacat ctgacagcca tcaactttcg
     3901 ataaaatatg ttcgtattta aacttttgaa ctacaacatc cagattaatt ttctaatctt
     3961 gtcgaacaag tcaaatatat cccgaaaggc cattggtaag cggtgatggg atgaacttgt
     4021 tggagcacga ggcgaagggt cttttcagac gttaccggat agcaacacct cggggattgt
     4081 tctacaagga catgaatggg atcgctggct ccttggtgaa catgaaattt cccctgatgg
     4141 taaaggccca gaccacccgg ggaggccgcg ggaaagcggg tggcatacgc accgctctgc
     4201 atgaccagga ggctttggag gcctgtgaga ggatactagg aatgcacata tccggaatga
     4261 gggtgcacgg ggtgctgctg gaggaaatga tcgaagcctc tcgggaaata tacctggcca
     4321 tcaccatcga ccaacgttcc cgctgtccac tcctgctcgc gggatgcgcg ggaggaatgg
     4381 acgtggagaa catgcccccg cacaccatga gaagatggac cttggacccg ttggaacctc
     4441 tttcggacga ggtgctcgat caagcctcgc attttctatt gcatggagac ccggggacca
     4501 aagaggtaag gtcgaccatt ggggccatgt ggagattgtt ccgcaacatg gactgtgagc
     4561 tggtggagat caacccattg atgatcaccg attctgggaa ggccatcgct gcggacgcca
     4621 aggtggcgat cgatgatgat tctttgtttc gacatcctga gttccgcgac aggtacgggc
     4681 gcgacctcac cgaactggag aggctggcca aggacaaggg gttcaacctg gtggagctgc
     4741 caggcgacat cggggtgctg gccaacggtg ccggcctgac catggccgcc ctggacacat
     4801 tacagagata cggtggcagg ggagggacct tcctggatct gggaggtacg gacgacccgg
     4861 accgaatatc ggaagccctg ggactgcttt cctatgatat ggccagagga cggatacgat
     4921 ctctattggt ttgcattttc ggaggcataa ccagatgcga cacggtggct gatgccatga
     4981 tgcacaccat aactgacagg aacgtcaagg ccaggacggt ggttaggtta cgtggaaaca
     5041 acgaggacga ggcggcccag atgctccggc tggcgaattt caacgtgcag atcgatcttg
     5101 acgacgcctg cctgcaagcg gtgaaggtgc gaacatgacc agaaacgccc ttctgaccaa
     5161 tcacaaggtg ctggtccagg ggatcaccgg caagcaaggt cagaaccata ccctccagat
     5221 gctagaatac ggcaccaaga tagtgggggg cgtgacccct ggcaaaggtg gtcgttccgt
     5281 ccatggcgtt ccagtgttca acgatgttca gaaggccgtc gagcgaacgg gagcgaccgc
     5341 cagcgtggtg ttcgtcccgg cggaccacct taaacaggcg gcggtggaag gaatggaggc
     5401 cggcctggag gccatggtag tgatcacgga acggacgccc ctgcatgatg ctatgcaatt
     5461 actttccatg gctaggaaaa agggagtgac gatactgggc cctaactgcc cggggctgtg
     5521 tctggtgggg gagagcaagg tgggtgtgat gcctaaccgc atcttccgca aagggaacct
     5581 ggccgtaatt tcgcgcagtg gcaccttgac ctacgaggtg gtacaggcgc tcagctcggc
     5641 cggactgggt cagagcatcg tgctgggttt gggcggagac aggttgctgg gaaccgatat
     5701 gcgcgaagcg gtggagatgg ttctggaaaa gagaccatcc ggggtgatca tgataggaga
     5761 gataggaggc cagatggagg aggaggcctc cctggtgatc aaggagatgg gggcagagaa
     5821 cgtcttcgca tacgtagcgg gagtgtctgc gccgccagct aaacgcatgg ggcacgccgg
     5881 ggcgatagtg tccggccgta ccgggggagc ctgggacaag atcagggccc tggaaggctc
     5941 aggagtcgcc gtaggaagct cgctgggaga cctggtggac ctaatatcca ggcgatctcg
     6001 cacgtgacct ctaagttttg ccatcaatat acatagtata ggaatggcag aaaaccttat
     6061 gaagggagag cgcctagtaa gagaatagta gcaataacgg cagtagccac ctacaactgg
     6121 ctgcgataag aaaccgttat ataatggaac tgtagtagcc ggttccactc gcgaagtagg
     6181 cgagtgtgga agcatgaata tgcggggaaa ctcgtatagg taatgcttaa atataccctc
     6241 aattattggg ggactcacgc gttccagcca tgtgttggag cgaagtgaga agtgctcatg
     6301 cacccgtaga gtaaccctct tcggggaagc ggaggagaat cctgggaatt tggaagaggt
     6361 ccccggtgat tcgttgatac caatcatacg caacctggac gtttgttaag ccgacaatgc
     6421 atagcggcgt ttgctacgcc gactggggaa tggctcggtt cgggtgccga agaaggtcgt
     6481 gccaagctgc gataagcatc gggtaggtgc atggagccta tgatccgatg atgacctaat
     6541 gcgacttcgt aatcttcgga ttgttccgta aggaacggga acgcggggga tcgaaacatc
     6601 ctagtacccg caggaaaaga aatcaatcga gataccgtga gtaaaggcga tcgaaaacgg
     6661 tacagggcaa accgaatccc catcagtaat gatggggaaa tgtggtgtta tgggcccggt
     6721 tacatcctta agacaaacca gagatctgct ggaacgcagt accatagagg gtgatagtcc
     6781 cgtatggaca aatcgagagg atgagttccg gtgtccctga gtaacgtgcg ttggatatcg
     6841 cgcgtgaatt tgggaaacat tcatttccaa ccctaaatac accccgagac cgatagtgca
     6901 gtagtagcgt gagtgaaagc tgaaaagtac ccttgacggg aggttcaaag agcctgaaac
     6961 cagtcggcta taaattgtat gggcatgaaa gggaaaccag tgttcatacg tccgtttcga
     7021 aaaacgggcc atggagttct gttcaatggc gaggctaaga ggatcatcct cggagccgaa
     7081 gggaaaccaa caagtccgca accgcaaggt gagggacgag gtgcgctcgc ctggagtcat
     7141 tggagggaca cccgaagcca gttgatctat acctgggcag gttgaagcct ttcgaaagga
     7201 aggtggagga ccgaaccggt aatgatgtgc aaatctttcg gataacctgg gtatagggat
     7261 gaaaggtcaa tcaaagctgg aaatagctgg ttcctcctga aactaatcgc agttagatct
     7321 cggtggaggt cgatcgtgtg gtagagcact gatcgggagc ttagggggag aaatccctcg
     7381 gctccctgtc aaactccgaa catgtggtca ccgtagaagc cgggagtgag ggcatccggg
     7441 gtaagcttga tgtccatcag ggaacgtaac ccagccaata attaaggtcc ctaagtttcg
     7501 gttaagtgta ataacaaagg gagtctgtag tccaagacaa ctgggaggtg agcttagaag
     7561 cagccatcct ttaaagaaag cgtaacagct caccagtcga gattataggc cccgaaaatg
     7621 gacggggcta aaccgagcac cgatattatt gagcaccgca aggtgatctg gtaaggaggt
     7681 gacaggcgtg ggcagaagct aggccgtgag gtctggtgga ccgcgtttgt atatggatca
     7741 tggcaggagt agcagcaaag aatggtgaga atccattccg ccgtaggggc cagggttcct
     7801 cggcaatgtt cgtcagccga gggttagccg atcctaaact attacttaat cggaaatagt
     7861 gaaagggaaa caggttaata ttcctgtgcc gcgtcagatt ttgcatcatt cttgacacat
     7921 cgggataaat ggaataatct tgtctggtta ttcaagtgta taaactgagg aagaaccgta
     7981 atggtgtgaa ctcggtgaaa gcgcgagcag ggggacgaaa gtccccttcc gtcgattcct
     8041 ggtgtccgtg aaaattgagt gattaataca cctgacgcgt tcgtaccaag aaccgacaca
     8101 ggtgccccta gatgaaaagt ctaaggcgtg tcggcctaat cgatgcgagg gaactcggca
     8161 aattagcccc gtaacttcgg gataaggggt gccagccgcg agagtggctg gtcgcagtgg
     8221 caagggaact ccgactgttt aataaaaaca cagatcgctg caagtccgaa aggatgtgta
     8281 tagcggttga agcctgccca gtgacggtat ctgaaactcg ggtccaaccg aacgaaggac
     8341 cgttaaacgg cgggggtaac tatgaccctc ttaaggtagc gtaatacctt gtcgcttaat
     8401 tggcgacttg catgaaggcc caacgagagt tctactgtcc ccgcatcgaa gccggtgaaa
     8461 ctaacagtac tggtgcacag tccagtatct tccacctgaa agcgaagacc ccatggagct
     8521 ttactgcaac ctgttgttgt gatatgaatt ttgatgtgta gggtaggcgg gagacgttac
     8581 ccaggaaata ccgctaggta ttctccgagt caacgatgaa acaccgccct tcagacttcg
     8641 taccactaac ttcgtcagaa ggacaccaat aggtaggcag tttgggtggg gcgccacgcg
     8701 ctcaaaaaga taacaagcgc gcccaatggt cagctcaggc aggtcagaaa tctgccggtg
     8761 aatgtaaggg taaaagctgg cttgacgcgg atccggacaa caaggatcgg cgatacgaaa
     8821 gtagggccta gcgaaccaat caaccttctg aatgggggtg attgatgaca gaaaagttac
     8881 cctggggata attgagttgt cgccagcaag agttcatatc gacctggcgg cttgctactt
     8941 cgctgtcggc tctccctatc ctggcggtgc agcagctgcc aagggtgggg ttgttcgccc
     9001 attaaaaggg atcgtgagct gggtttagac cgtcgtgaga caggtttgtt gctttttggt
     9061 ggaagtgtat tgatgcctga cgagaaggac ccttgagtac gagaggaacg ggggttcggt
     9121 gcctctagtc aatcagttgt ccgacagggc atgctgagca gccacgcact actggataag
     9181 agctgaaagc atctaagctc gaagccacct tgaaaaagag gcatcttagg acgctcataa
     9241 ttgatgagct tgatagaatc gggatgtacg catcgaggtt tttccgagat gttcagtccg
     9301 cggttactaa cgtcttttgc cgcgaagcat tgtaggcttg ccttaatggt aggctttggc
     9361 ttaaccgtta aacaggttgc gtttgtacct cttccaaaga aatatttttt tatttattat
     9421 caggtggaat attgttgcgt atgatttttc atgagcttta gctctggatc attctttgat
     9481 ctttgtaatg atcacatgaa atgagtggcc taggggctgc actttgacga tcatcttaag
     9541 acgagaatca gaggaaccat caccaccgta tatttaggtc gatgggcggg aggaggaccc
     9601 ggccgtcaag caatcgaata gcctttagtg acattcgatc caggttgtag cgttatcgat
     9661 ctacggtcaa ttttcatcca tattagtgta aattttgttc aaaatatcca atggctgacg
     9721 aaacttggga caatctataa ctacgatttg ctggatattc aacagccgat gtcattcaat
     9781 actgtgaggg gtgcgctttg agcgatatac ccctatacgt ccaggagatg ctcaagagcc
     9841 atccctgtta caacgaaaag gcccacaagg aattcgcaag gatgcatctt ccgatcgccc
     9901 ctcgatgcaa catacaatgc aactactgca atcgtaaata tgattgtacc aacgaatcaa
     9961 ggcccggggt caccagcgaa gtactgtcgc ccgaggaggc cgtaaacaag atccgggtgg
    10021 tcaaggagaa gatcccccag ctcagcgtga taggtatcgc cggaccgggc gatcctttgg
    10081 caaatgagga gaccttcact accctggagc tggtgaagga agagttcccg gagctcaccc
    10141 tctgcctgag caccaatggc ctcaaccttc ccagatcggt ggagaggctg aaggctctgg
    10201 gagtcaagtt cgttaccgtc accataaacg ctgtggaccc ggaggtcggg tccaagatat
    10261 acgacttcgc gatctgggac ggcaagttgc tgcgtggaaa ggacgccgcg gaacagctgc
    10321 tcaagaatca gcttgagggc atcaagatgt gcaccgaggc cgggatcctg gtcaaggcga
    10381 acatagtcat ggtgccgacg gtgaacgccg atcacattcc ggacattgca aagaaggtca
    10441 aggagctggg cgcatatatc gtgaacatca ttccgctcat acccgtacca ggcaccaggt
    10501 tcgagcatat gcctgcgcct accccggagc agcgcaagat gctacaggac ctttgcgagg
    10561 gagacatacg ccagatgcgc cattgccgtt tctgccgggc cgacgccatc ggtatgctgg
    10621 ataacgatag gtccgctgag ttcgcgcata tcacctgcgg agcccgggaa gcaccgcagg
    10681 gtggaccggt gggcattcag atggaaggca ctgccaagca cagagtggcg gtggccacct
    10741 cggacgggaa gaacgtagac cagcacttcg gccagaccaa agagttctgg ttgttcgatg
    10801 tcgaagatgg gaagttgaaa ttggtggaca aggtacgcac cgacccgttc ctggaggaat
    10861 ccatgttcgg accaaagcat cacaacaaga tcgagcggat ggtgtccgcg ctgatcggtt
    10921 cggatatcgt gctcacctcc ggtttcggag tcaaggcaga tgccgagatc agggccaggg
    10981 gcatgcgccc ctacaagaag gacggaccgc tggatgaagc ggtgctctgc gcggtgaggg
    11041 accttttcga ggagagggcc aaggtctttg agtgatccga tgaaagcgtc caggttgctg
    11101 gtggaatgcc ttaaggcgga gggcgtcgag cgagttttcg ggatccctgg cgaggagaac
    11161 atggatgtca tggacgacat tcaccaggcg ggcctcgagt tcgtgctcac ccgacatgag
    11221 caggccgcgg cattcatggc ggccacggtg ggaaggctta ccggccgacc cggggtctgc
    11281 ctgagcacgc tgggtccggg agccacgaac ctggtcagcg gcgtggccga cgcctatctc
    11341 agcaacttgc ccatggtggc cctggtcgct caggccgggg cggcccgcgt ggaccctccg
    11401 cagaagcagg tactggacct attggccatg ttccgccctt tgaccaaaag ggccctggac
    11461 atcgggggac ctgatgatat cccccagtcg gtgaggaaag cgttcgatgt cgcctcgtcg
    11521 gaaaggagcg gcccggtgat gctgcaactc cctgaggacg ttatgaggaa ggaagcgact
    11581 ggaaacccat cacccatccc taggaaaagg gcgaagagag caagagagct ggacatcgcc
    11641 aacgttcgaa atatcctgtc atcgtccgaa cgtccattgg tcttggccgg gcacggagcg
    11701 ctgcgtgaga acgccgtttc ggcgctcatc aagttctgcg aatcctggaa cctgccggtg
    11761 ggttgcacct ggatggccgc tggtgcggtc cccttcgatc atgaactgag cctgggcacg
    11821 gtgggcatgc gcaacagcga cctggtaaaa ggttcctacg aggaagcgga cgcggtccta
    11881 ctggtaggtt ttgattccac cgagttccaa ccgcaatatt ggaaccgcgg acggaccaag
    11941 aggatcgcat acctcggccg gtccagaccc ataccttgta ggaacatggt gctggaatcc
    12001 accgtcctgg gcagtttgac cgattccttg ggacgattgg ccgcggacgc catacccagg
    12061 aaaagctggc attccgtaca ccgtcagaag ttgatcaacg accttaccgg aaaggccgaa
    12121 ggcccccagg ccctagtgca gaccatgcgg cgctgtatgt ccagggacga catcatggtt
    12181 agcgatgtcg gagcacacct catctggctg gccaagtatt atccagctta tggcccaaac
    12241 actttgttgc tgcagaatgg gctgatacct atgggcatcg ccataccatc ggccatcgct
    12301 gccaagatgg tccatcctga aagacgggta tgcgcaacgg tgggagacgg agggttcatg
    12361 atgtcctcgg cagagctgga gacggcgaaa cgtctgggag tgaacttcgt cacggtgata
    12421 ttcaacgacg gcggattggg cctgatacgg gagaagatga cccgtagcct cggccgaagc
    12481 tcgaacgttg agcttggcaa tcctgacatc ccgaccttcg cccgctcgtt cggagcggaa
    12541 ggatattctg tcaccggaaa ggagttcgaa acggtattcc gggattgtct ggaccgggac
    12601 gcgttagcgg taattgacgt gcgggtagat tactcgcaaa atcaccacct cttctgaacg
    12661 aataaatatt cgcagctgcg ttcgaagaac gggtatgaaa tgacgctgaa gaaggccacc
    12721 tttgccgcag gatgcttttg gggagtggaa gccaggttca tgaaggtcaa gggagtggcc
    12781 cagaccgagg tcggctacat gggcggccac accgaatcgc caacctaccg ggacgtatgc
    12841 acggaccgca ccgggcacgc cgaggtcgtg cagctcacct atgacgattc cgtcgtcagc
    12901 tacgatggtt tgctggacgt gttctggagc tcacacgatc cgacccagag gaaccgccag
    12961 gggcctgacg tagggaccca atatcgaacg gccatattct atcacgatga ggagcaacgt
    13021 tcggtagccg aacgctccaa agcgaccttg gacgccagcg gccgttttaa aaggccgatc
    13081 gccaccctgg tggagagggc cggaccgttc tggaaggcgg aggaatacca tcagaagtac
    13141 ctgcaaaaga agggactcga tacctgccac atctgactgg ataatacggc cttccatgcg
    13201 atggcatgac aatattctta taacgaccta gaaataacgc cagttatgac cggttcggag
    13261 ttcgacctcg ccttcttcca ggagaagggt ttcatgcgca agcaatgccc caagtgccag
    13321 cggcacttct ggagcctggg cgactggcct acttgcggag aaccgccttg cgaggagtac
    13381 accttcatag gtaactcccc catgaaccgt aagctcgagc tgcacgagat gcgcgaagcg
    13441 tatctgggct tcttcgagga gaacggccac ggccgggtca agagataccc gatcgtggct
    13501 cgctggaggg acgacgtgtt cttcacccag gcctccatct atgatttcca gccctgggtc
    13561 ctgaacgggg tcatcgagcc tccctacaac ccattgacca tatcccagac ctgcgtgcgt
    13621 ttcaacgaca tcgacaacgt ggggaagaca ggcagacact tcaccttctt cgagatgtgc
    13681 gcccatcacg ccttcaacaa gaaggacggc aagttcatct atttcaagga ccggacggtg
    13741 gagctctgcc accgcttctt caccgagcgc ctgggaaccg acccgggcaa gatgcgctac
    13801 atcgaggagt ggtgggaggg cggcggcaac gccggacctt gcgtagaggt gatcctggac
    13861 ggagtggagg tagccacgct cgtgttcatg atgtaccggg acaccccgga cggacggaaa
    13921 cccatggaca tgaccgtagt ggacactggt tacggcctag agcgcatgac ctgggtgtcc
    13981 cagggagttt cttccgccta cgaggcggtc ttcggaccgg tggtcgattg gctcaagggc
    14041 ctggcgaacg tggagcctga caagacggtc ctgaccgaat attccaaggt ggccggggcc
    14101 accaacatga agacggcggc cgatgttcgc cgcattcggg agaccaccgc cgagaggata
    14161 gggatcagct acgaagagct gatgaagacc atatcccccc tggaggacat atacgtcatc
    14221 tgcgaccact cccgggcgct gatgcttatg ctgaacgacg gcgtggtgcc ctcgaacgtc
    14281 agagagggtt acttcgcccg catgctggtt cgccgggcct tgcgctccat acgctccctg
    14341 aacctggaca tccggctctc cgaggcggtg ggcagacagg tggaccattt ccaggacata
    14401 ttcccggagc tgaaggagaa ccgcgaggac atcctgaacc tggtcgaggt ggaggaggag
    14461 cggtacttcg agaccttggg aaggggaaaa caactggtcg gtcggctggt caaggacctc
    14521 aagaaggggg agaagctgtc caacgagaag ctcatcgagc tgtacgattc ccatggactg
    14581 aacccggaga tcgcccagga attcgcgccc gggcaaattg acgtccctga taacttctac
    14641 atgcaggtgg ccgccaggca cgagaagccc gaggcggatg tcgcggaagc gaaggagcgc
    14701 ccggagaaga tgccggagac gcgaatgctg tactacgaag atccggagct ggtggagttc
    14761 gagggaacgg tcatcgccga gatcgatggc ggaatcgttc ttgaccagag cgccttctac
    14821 ccggagggcg gcggacagga atgggacctc ggcatactgg atggaaagag ggtctgccgg
    14881 gtcatcaaga tcaagaccac catcgtccac ttcgtggaag ggaagaaccc tgcgataggg
    14941 gcccgggtaa gaggcgtgat cgaccttgag cgtcgccagc agctgatgcg ccaccacact
    15001 ggagcacatc tgataaacgg ggtcgcccgc aacctgttcg gcaatcacgt ctggcaggcc
    15061 ggagcccaca aggcggttga ccaggcccgt ctggacgtca cccacttcga gaacctcagt
    15121 accgagcagc gcgatacgct ggagagagag gtcaatcggg tggtgctgca agatcggccg
    15181 ataagcatcc agttcatgcc ccgggacgag gcggagaagc tgcacggcta ccggctgtac
    15241 cagggcggtg ccgtaccggg gaagatcatc cgggtggtgg aagtgcaggg tctggacgcc
    15301 gaggcctgcg gaggactgca ttgctcgcac accggaatgg tcgggccggt ccgaataacc
    15361 cgcaccaagc gcatccagga cggtatcgtt cgcgtggagt acaccgcggg aatggctgcg
    15421 gtggccggaa tgcaatccga caagcgcctg gtcgaggaac tgggcgattc gctcaacgta
    15481 ccaggcgaga agctgcccga gaccgtgacc aaactgcagg acgacctgcg cgaacagcgt
    15541 aagagcatcg aacacctctc gtcggtcatc aacgacatga gcgtgaagga gctggtctcc
    15601 gaagcgccca gggccggaga ggcccgcgtc gtcgtgcacg aggcgctgcc gggcgaggac
    15661 cccgaggaga tgtccaagca gctggcgtcc atgccttgca ccgtggtcgt gataggggtc
    15721 ccgggggaga gagcgaagtt gctcgttgcc tgttcctcgg acgtcaagat ggactgccgc
    15781 aaggccctga aggacatcat ggccttcatg ggtggaggcg ggggcgggaa gccggactac
    15841 gcccagggcg ggggcgggga cccagcaagg ctgagggacg ccctgtccaa agcctatgac
    15901 gtcgtctcca aggagatcgg catctgaaac ccctccccat acctcttttt cgatgcagaa
    15961 cggttatata cagcctcaag cttggcatat ccgacagaat cgatactgtt gagggagccc
    16021 ttcgcaatag gggcttgttc ccggaccggt agccctatcc ggagatggga actgcaaacc
    16081 gcgctcttcg gtgcggggcg tacttcgcga gggcgagctt cgattcgcga tcaccagcga
    16141 gggatactct tggctgaagc gaaaaagact actacaccag aggagaagga cgacttccgg
    16201 tacattgtcc gcatagtgaa cacggacatt gacggcaaca agcccaccgt ggtcggactg
    16261 cagagcatta aaggcgttgg aaagagggtt gccgaggtca tcgtccggaa ggccggcgtg
    16321 gaccgatcgg tcaagatcgg ctccctggac gaggcggcca ccactgaact gaccaacctc
    16381 atttccacct atgctgatta cgcgcccaac tgggccatca accggcaggc ggactacgag
    16441 accggcgagg accatcatat ggtcggcgtc gatctggaca tggtcctgaa ggacgacatc
    16501 aaccgcctga agatgatcag atgctaccgc ggggtgcgcc acgataccgg acacaaggtc
    16561 cgcggtcagc gcaccaggtc caacggcagg aagggtctga ccctgggcgt ttccaagacc
    16621 cggaaccagc ccgccgctaa gaaggaggcc tgaacatggg tgatccaaag ttcccgagaa
    16681 ggagctacga cactccctcc cacccctggc agggcgagcg cataaaggag gaggccatac
    16741 tcgttaagca gtacggcctg aagaacaaga aggagctgtg gaaggccaag accatcctgc
    16801 ggaacctgcg caagcagtcc cgtgatctcc aggctcgcct gaggatcggg gagcaacagg
    16861 ccaagatgga gaccgagaac ctgctgcgca agtgcgccag gatcggactg ttgcccatgg
    16921 aaggcaccag gctggacgac gtactgggac tttcggacct ggcactgctc gaccgccgcc
    16981 tgcagaccgt ggtgttcaac cggggactgg cctcgaccgt cggtcaggcc aggcagttca
    17041 tcgttcacgg gcatgtgtgc atcgacgacc agaaggtcac catacccggt tacatcgtca
    17101 cccgtgagga tgaggacaag atcattatca acccgaggtc gcccatcgcc aacgagctgc
    17161 acccgctgaa gcaggtccaa gagaccgctt ccgaccgggc ccgccgcgtg gaggctgagg
    17221 acgccaagaa ggacctgggc aagaagaagt tcgtcaagca tgtgcccaag gagatcgagg
    17281 ccgctgtcca ggacgtcgag gatgtcccga acgagctgcc gaccgaggag gtgaactgat
    17341 gggcaagtgg ggaatagcga acgttttcgc cagttacaac aacatcataa tcactttgac
    17401 cgacgtcacc ggtgccgaga ccataaccaa gtgcaccggc ggaatggtgg tcaaggcggc
    17461 caaggacgag tcctcgcctt acgcggccat gagggccgcg gagaaggtgg ccgagatagc
    17521 caaggaaaag gggatcgatg gcattcacgt caaggtgcgc gcaccaggcg gcaaccgctc
    17581 cacttcacct ggcccgggag ctcaggcggc catcagggcc ctggcccgcg ctggtctgag
    17641 gatcggacgc atcgaggatg ttacccctgt tccgcatgac ggcaccaaga agaagggcgg
    17701 tcgccgcggc agaagggtct aaagaggcgc tttatgcaca taaagatgct agaggagatg
    17761 gagaccaggg ccaagttcct ggtcaccgat gccagtccag agaaggtcaa cgcgctgcga
    17821 agggcgttga tgatggacgt ccccaagttg gcgatcgacg acgtggagtt ccacctcggt
    17881 tcgtcggtgg acgccgatgg caatgagtac gagagcatca gtccggtgtt cgacgagatc
    17941 gtcgcgcaca ggcttggcct ggtacccata cccaccgacc tggacctgtt cggattccgc
    18001 gaccagtgct cctgcggtgg cgagggctgc ccgaactgca ccatctacta ctccctggag
    18061 aagagggggc cgtgcgaggt gtattccggt gaccttagct gcctgggcga ctccaagttc
    18121 caggtcaagg accagctgat ccccatcgtg cgattgggcg agcgccaggg aatactggcc
    18181 tacgccatag ctgagctggg gaccggccgc aagcacgcca aatggcagcc gacccatggt
    18241 gtgggataca agtacttccc gaccgtgacc atcgaccagt ccaagtgcga caacggcggc
    18301 acctgcatca aggtctgccc caaggcggtc atgaacttca aggacaagaa ggtgcaggtg
    18361 ttggacaacg acgcctgcgt cctctgcgag gagtgcgtga aggtctgccg gaccggagcc
    18421 atcaaggtaa agtggtccga caacaagttc ctcttcgagt tcgagaccga tgggtccctg
    18481 agcgcgaggg tggcactgtc caaggccctg gagtcgttgg agaagggctt cgacgagttc
    18541 agagagaagg tcgcttccct ggaaggctga aacggcggtt accccgccat cttcccattt
    18601 tcttatattt tagaaatcat ccaggcaaat cgttctttta ccttccgacc cgctcggccc
    18661 ttcctcgacc ggatcgtcgg catctgggtc gctgtgaagt tccagcgact gttcctctcc
    18721 cccttcatcg taggagtcca agggcgtcga tgatatctcc tctccgaata tcgaggtgat
    18781 cgacttctct atcaaccgta tccgctgctg ggtgtactcc gagacgccgt aatcgcgccc
    18841 gatcctgctg gtaacttcca gatacttctt cacgctagcc tcgtacaccg tcaggttcag
    18901 cttgttgccg cagtagcagt gcccgctgag cggtacccgt cggtaacttt ccgcgcactt
    18961 ggtgcagcgg aacttctgtc cagagaagct cttcaggtta ccgatgaggt ccggcaggaa
    19021 gtgcttggtg atgacccggt gcaccacgtc cccctcgtcc accgccctga tgcgcttggc
    19081 cagctccagc tgggcggtca tcttgtccat catggtctcc agggtcttgt acgcggattc
    19141 gtccggccct tcggcgatgt cgtaggtatc gtgagtgaag ccgaacccct cgtactgtaa
    19201 cagcgatttg atgcggtcgg ccaccaggtc catcttggac tggatgtcct tggggtggcg
    19261 gtaatccacg catgcccggt agaactccaa tggatattcc caatgcacgt cgatgttctg
    19321 cgcttccttg tccacctcgt tagggtccag acgtaacgct agcaccagag gggcgtccat
    19381 cagaccgccg cgactgtccg ggaggtaaga acgggagaag ttgagaagac cgtccagcag
    19441 tagcaccacg ctatcctcgt ccccgtcggc gttgcgcctc ttggcagcgt gaaagaacgg
    19501 gtggccgaaa cacacgctgg ccttggtgaa acctatgatc cggcagagga tcccgcccga
    19561 agtgtgaggg gccagtccga tggccagatg gccgattatg tcctccttgc tccgggcgtt
    19621 gtaatgacgg ggcagttcgt agaacctttc caacaggtcg tcgatgaagt cggccactcg
    19681 gaccatgaag tccccgcagg aattggaggg aacgatgtcc tggaccttta gctcacacaa
    19741 ctgctcggga tccgtcagcg gctgatcgta tatgtcgtgg tcatagccga gctctaaggc
    19801 cttctgtacg ctcagaccga tctctcgagg gcggaaatgg gtcaagggga cgtccgtgag
    19861 gtcaaagcgt atcgtcccgt ccttgttgac gtatatctcg tgcttgcgcc gcaggatgcc
    19921 cttctccaag ggctcggggc acatgtcctt ggactttagc tccttctccc ccttgagctt
    19981 gggcaggatg gacctttccc ccaaggcctt gcgcgctttc tcgagctcct cggcgaggtt
    20041 caccggaacg tccttggaat cccccaccgg cagggtgtgc cctccgcagg gacagcggta
    20101 gtatacccga tgctccccgc acagctggca tttcctgacc cccagcttca cggtgatatt
    20161 gcccttgcca gccgccttct ccataaggcg ctgcggcccc ccgtgcattc ctatcgggaa
    20221 gatggtgtgc gagggggctt tcgctgaacg gtccttggcc ttctccggcc gggccatgcg
    20281 cgaacctatc ctggtcacgg cgcggggatt gaccttgact cccgtgcatc tggacaccgc
    20341 ctccatgacc gtcgcccctt ccaggggaac ccggtcctcg acccttccct cacctagaag
    20401 tcccagaccg gccaggagcg gctcggagta cctctcgatg attacgtccc catcgaccac
    20461 ctggtgcagg gcgcccaggg tctccaaggt acgcttggac cccggttcca atggaacgcg
    20521 cagggaaccg ccagcgaact tgccttggga cagtatggag accctcagcc cctgtaaggc
    20581 ctctagcgac aggtcgtacc agaagaggtt gtacttggga tgaagcggaa cgttgtaacg
    20641 cttggacata tccagagcgg tggcgaagtc ctgggggtcc tcccagccat ctggaagctg
    20701 ccagtcgttg gcggcgtata gctcggcgcg atgccattcc aggtcgtagt ccccggggac
    20761 cagcacgtgg ttgttctcca cgaactcccc gaacgggaat aggatctcgc cgacgtcgac
    20821 tatctccttc attcgctcct tgacggcctt gaactccgct acggtgttgg tctgcaccag
    20881 gtcgccattg tccaggagca atatcggtcc ctccagacgg tcacagggcg tcaccgcccc
    20941 ggcctttccc ggacgttcga tcttgatctg cgtgcctatc gctaaaaagt catccagggc
    21001 gaacatcgtc gccgggctca gggcaatggc cgccagcccg gtggtcctgg ccctcccgta
    21061 gcgaaggcgc agtccgcccg gccgggaagg atgtccgatg accggtcgtc cggccacgat
    21121 gtccttgagg tacttgtagt cggggaccac cttgacctcc ttctgctccg tggccgcccc
    21181 cttcttcagc ttcaagtatt cgcttatgaa gtcccatcct tccaggccca gcttcttgac
    21241 gtgcttctct atcttgggcg ccttgaggca cagaccttcg gctatgacca ggcacacccc
    21301 tccgcgaacg gcattggtct tgatccgcgg aagattgcgg tatccggata tctcagcgtc
    21361 ctcggtcttc tccccgtcca cgcacaccgg gcagttccgg tagatgatct cgatctcctg
    21421 gttgctgggg gtgaactgaa gatgctggat ctgcttgtag agaggtatct cctccttcag
    21481 cctctccacc tctccgacgg tgggcttgta ggttccgata ccgaactccc ggcgcaccac
    21541 gtccgcgatg agcacgctca tggcctgagc ggtccctccc gccgctcgta tcggaccgtt
    21601 gaagaacacc gagatgtact ccgtaccgtc cggattggca ttgatcttga ccccggcgat
    21661 gccgacgatg ggagccacga gtatcccttc ggtgagaacc gagagaccga cccggaccgc
    21721 ccggtccatg gccatctccc ttccctcgtt ggcggcgacg gcctccatgg ccagctcctt
    21781 ggcgatgaac agagaaagtt cctcacggct ctcgatgcgc ttggccagct cccttatacg
    21841 ttccgccacc ccttccacgt gccagtcggc cagttgcttc tccacccggg ccgccaggtc
    21901 ctcggcctgc ggtatctcca ccatcgtgct ggggtccagc cctttggccc gggcctcggt
    21961 ggccagagcg tagcagcgct cgttctcctg gaaaagaccg gagaagtatc ggcgcatcga
    22021 ttcgctacag gccagttctt gcaagggcac cccatccgca ctaaggggag agaaaattaa
    22081 taagtttgct tagaacgcgg gttcgaccgt ttccagatgc ttcaccgact cgcgcagggc
    22141 ggccatgacc tcttggacac cgaccccggt ggccgcgctc atcttgagcc ggtcggaacc
    22201 gctgtcgatc atgtcgacct tgttctccac gaccaggatg ggcacgtcgg ggaacaatgc
    22261 ctttacggac tccagaaggc gcagctgccc ttccatgagg tagccgcagc tctccgaggg
    22321 gtccaatatg aacaggatgg aattggccag gtgcttgagg gcggtgaccg cctgcatctc
    22381 tatgcggttg cggtactcca actccctgtc gagcagacca ggcgtgtcta tcacttgata
    22441 gcggcggtgg ttcgcctcgt gtatgccgac ctcgatgccc ttggtggtga agggataggc
    22501 ggccacctct ggctcggcgg ccgagatggt tcgcaggaac tggctcttgc ccacgttggg
    22561 aaagccggct atgacgaagg tgagcatgtc gtcattgaaa tcagggacct tgcggaactc
    22621 gttcctggcg taggcgagga actccaggtc cggaccgacc ttgttcacca cggatgatgc
    22681 ccgaccgtag taggctttgc gggcgttgtc ggcggcgaac gtagatgtgg acgtcatcac
    22741 cttgctggtg tactgtttct gcagctcctt gatcttcgaa gcggcccagt ccaggttgcc
    22801 cagggccttc ttcatcttat ccactccgac cgtgacctcg atcatctcgg ccaggaagtc
    22861 agtgcgttcg ttgatgctcg ggaacgcctt gacgtacttc atgagggtgg acgaaatgac
    22921 atccgtggcc gatgcgattc gggccatgga cttgcgtttg acgagctcga ccttgtccgg
    22981 cccctgcttg tcgatcttgt tgacctttcg gaacgccttg tccaatatct cgtccgaggt
    23041 tagaatggtg gggacgcgct tcctaaggtt ctgcacgttc cgtcacaaag tagaggtagt
    23101 ttataaaaca tggctccagc catgacctat tccttgcgtg ccgatccagt tctggtcaag
    23161 gacgaacgcg acctactgga cggagatgac cttcacctgc tcgtactgct ccgggatgtt
    23221 ggtacggacg gcgctgccgc gaccctcggg aacacaaaag gaacggtgct ccgtaaggtg
    23281 cgtcggatag aacggaaggt gggcggtaag atcttggaga atggaacatt aaaccggtac
    23341 ggaaatgagc tcgtcgagag gatggagctt tacgtacgat tgttggaggc tcaactggag
    23401 atcctctggc gcaacccgag cttgacctgc gacggcctcc tacttcgtga gggaaaggta
    23461 cttctggtca agaggggcag ggaaccattc caagggcgtc atgcattgcc aggaggcttc
    23521 gtggaatatg gagagagcac cgaggattgc gtggtccgcg agatcaggga ggagaccgga
    23581 ctggataccg aggtcgaacg cctggtcggc gtctattccg agatgggccg ggatccccgg
    23641 gggcatttcg tcaccttgct ttacttgctc agggagacgg gaggggatct ccaggccgga
    23701 gatgacgccg catcggccgg attcttcaag ctgtccgacc tgccggagct agcgttcgat
    23761 catgggaaga tgatcaggga cgggctgagg tccgcagaac atcctttata gccccgggat
    23821 tggataggga tgagcatggg gcaggatgac ctggacgaaa ctatcctgcg catgttgcag
    23881 ggcaacggca agttgtccat cgaagaactg gccgagaagt tgggacgatc gccctccacc
    23941 atccgggacc gaatgcgccg catggaagag gagagattga tccttggcta ctccgtcatt
    24001 gtggaccagg aaaggctgga tattgacgcg gaggcgctgg tcctggcgga catcgaccct
    24061 cagatggaag gcaaggccat gagcgccctg atgtccatgg aggaggtcgg cgaggtaatg
    24121 aaggtcaccg gcgagccccg cctgatgttc agggtccggg cttccgaccg ccaggagctg
    24181 ctcggattcc tggaccgcaa gataaggccc ctgggatttc gacgcttgga cgtccgtctg
    24241 atactggacc gcccggtgcg ttacccggga tcggtttagt ggatttgctt atttatccac
    24301 cattttctat atcctccgga tgcagaccgt aacctggttg gccctgctgg tgtttctatt
    24361 cacctatacc ctcatttccg tgaggagggt gcgcagcgtc agcatcgacc gtcccgccgc
    24421 cgccttgttc ggagcggtgc tgatggtcct gctgggtgtg gtcaccgccg accaggtgct
    24481 ggaagccatt gacctggaca taatcggtct gctgctgggc atgatgatca tcgtctcctg
    24541 cctggagata actggactgt tcgacagggt ggcggtgata ctggtgaaca ggtgcgcaga
    24601 ccgcttcacc ctgctgtggc tgagcatggg ggtcaccgcc ctgctctccg ccctgatctt
    24661 gaacgacacc gtggtcctga tgttcacgcc gatcctgatc aaggtctgcc gctccatcga
    24721 tgccaacccc gtaccttatc tggtcgggga ggccttggcc gccaacatcg ggtcggtggc
    24781 caccggagtg gggaaccccc agaacgccta catactcatc caatccggga tcacgttctc
    24841 ggacttcgcc ctggccctcg caccattggc cctgatatcg ttagcggtgg ccgtggggat
    24901 ggtcgccctg gtgttcagaa aggagatatt cgatggaggg ctgggcaaac cccgccctat
    24961 cgatcgctcg ctggtcatgg ccgccgcccc cagaaagcgc atggaagcac cgttcttcct
    25021 ggtgcttgcc gtcctggtgg cggtcttcat cggcttcacc gcctcctcct ggcttgggat
    25081 cccgatatcg ctggtggcat tcctgggtgg ctgcttccta ctgctggccc tccccctgat
    25141 gaagaaggac accggaacct caccgatcct gcgcggggtg gactggaccc tgatcctctt
    25201 cttcgtcggc ctgttcatat tgctgaaggg agtggagacc tccggcctga tggatatgat
    25261 gctctcctcc ttcgaggaca tgggggcagg catggccgga gtggccggcc ttaccgtcat
    25321 atcctcggtg ctgtcgaacc tgataagcaa cgttcccgcg gtgatgctgc tgtcaccagt
    25381 ggtaccggcg ggtaaccaaa cgctgtggct cagtttagcg gcatcgtcca ccctggccgg
    25441 gaacgccacc atcctggggg cggcggccaa tgtcatagtg ttggaaaagg ggctgagcat
    25501 gggcgtagag gtccgcctct gggactttgt caaggccgga ctgccggtca ccctggtaac
    25561 gttgctgata tccgtgctgt tcctgggaat ttgaaaagag aaaagaggtt ttaagggaag
    25621 aggtttggaa gatcagatct tcttggtgca gaaccaccag tcgtagcagt ccttgccctt
    25681 tccgacgttc ttcttccgct ccatggcggt cttgtaatcc ttcggcgggg gtatgatggc
    25741 ccggtcgccg acgagctcgc tgttcggcca tccctcaggg gtggccagac cgttcttgtc
    25801 gcagaactgc agggcctgca aggcacgaac tacctcgttg acgctgcggc cgatctcctg
    25861 cgggtagtag atgatcaggc ggacgatggc cttggggtcg atgatgaata cggccctcac
    25921 cgtgttgctg gcctttccgg ggtgtatcat ccctagccgc atggccacgt cgccgtggtc
    25981 agcgatgatg gggaagggta tcttgacgcc gaggttctcc tcgatccact ccacccactt
    26041 gatgtgggag aacacctggt ctatggacag tccgaccagg acggtgtcca tcttcttgaa
    26101 ctcctcggcc ttcttggcga aggcgacgaa ctcggtggtg catgtggggg tgaagtcggc
    26161 cgggtggctg aacagtacca gccactttcc cgctacatcc ttcggcaggc tcatcgggcc
    26221 gtgggtggtg gtcaccgtca tatccgggaa cttatcccct atcaatggca tccccattgt
    26281 atcatccatg tcttcacaca tagttatcac tgtgaagtca tacccatcat ggcaatattt
    26341 aaaggttttt agttttacat catttctgga catctggcta tgtgtgttcc attcgggtaa
    26401 ttatgcgccc gtcataaccc aattgtgata agcaaatcct ttaacggaaa taaaggataa
    26461 ataccgaaag acccatggga tagaacatgt ccctagccac tgacctttcg ttggtgttca
    26521 tcgtgatcgg ggtgctgatg cttctggtgg agatcagcca gcccggatca ttccttctgg
    26581 tgccggccac ggtgctcttg gccttgggag gcgtaggatt ggtgttcccg gatcttcttc
    26641 tgaccgtgtg gtccccgatc atcgcggttg tgatactggt ccctaccacc ttcctaacca
    26701 tcaagatgta tcagcgcctt gcgcccccgg ctccgcctca gaccacggtg gccacctcct
    26761 tgatcggcaa ggagggatcg gtggaaacgg aggtcgtacc gggctccctt agggggaagg
    26821 tcaagatagc caatgtcatg tggagtgcca cctcggcgat gcccatacca gtggggaagc
    26881 gggtgaaggt ggtccggagc gagggcgtgc acgtgaccgt agaggagata atccaataga
    26941 tttggagaag gtaatcatgg caatcggagt tgagatattt ggtttgttaa tactggccat
    27001 catcgcggct atcgtgatag tggtcaacgg tgtcaagatc gtacggccgt acgaacaggc
    27061 ggtctacatc cgcttgggca tgttcattag aatactgaac cccggcttca attatgtagc
    27121 cccattgatc aacgagacgg tcaaattgga cctcaggacg caggtcctgg acgttccgag
    27181 gcaggaggtc atcaccaagg ataactcccc ggtgaacgtt gacgccatca tctatgtgaa
    27241 ggttatcgac cctaagaagg ccttcttcga ggttaccgac tacagagcgg cgaccgtgta
    27301 cctagctcag accaccttga ggtcgatcat aggcgacatg gagctggatg agatactgtc
    27361 caaccgtgag aagatcaacc tcaagctgag ggacatcctg gacgaggcga ccgaccagtg
    27421 gggtgtcaag gtcgacgcgg tggagatcag ggagatcgac cccgctccga aggtcaaaca
    27481 ggccatggaa gagcagacct ccgccgagag gctgaggcgt gcggccatct tgaaggccga
    27541 cggcgccaag accgcggcca tcctcaacgc cgagggtgag aagcggtctc gggtgctgca
    27601 ggccgaaggc cttcgtcagg ccaagatcct ggaagcggaa ggagagaggc tggccatcat
    27661 cttggagagc cagggtgagg cccagaagct caggatactg agcgtgggag ccagcacgtt
    27721 ggacaccaag gccctgaccg tgctgtcact ggacgctttg aagaagctgg gtgagggaca
    27781 ggctacaaag atagtgcttc cgttcgagct gacccgcctg gtggagggca tctccgacta
    27841 tgtcggtgga gttcgcagca taccggaaag ggagatctcc aagcctgagg agatcgagag
    27901 gacggttggc aaggcagaca tcatcctggg ccccatacct acccaggaag agctccgccg
    27961 ggacatgaag gagctagaag tggccatggc ccaggagaga cgcgaggccg aggccatcaa
    28021 ggccgggacc cgtgtttccc tggagaagga ccgcgagtaa aaccctttcg ctcaaacctt
    28081 tttatttcat ttttattgaa gacccagggt gaccagggat ctcttggtca gccaaatata
    28141 caatttcgcc cgatggcctc agaatttgat cttccatcgg cgtaacatga agaaagcgat
    28201 tatcagtgta actgcgacca gcccgatgac atagggaagg tagtcgtagt tcggttcgaa
    28261 gatacctata ccagcgtaca gcgccatcaa tgcgtacacc tgagcctggt cgcgcaggtc
    28321 ctgctcatcc acccattccc cgttcttgac cgctgcacga gaatccaggg aggtgtgaat
    28381 gtgaccgttc gcctcgcctc ccacatcgtc gtagatcgtg agcggctggg agtagacgca
    28441 catggtgctg gtggattcca atccgcgacc gatgcctagg tccttccccc aggccctgtt
    28501 cagctcgttg gacatccaat aagggaacat gaacgaataa tggtcggaac cggccaggtc
    28561 ctggaaggaa tgggcgaccc ctagcctaga gcatgcctca tcagcaacga agttgagatc
    28621 tacctccccg tccgatccag ctagggtgac cttcagatcg gaagacccta tggaatcggc
    28681 gattatgctg gccacctggt tccccatctc acctcggtgc atgctcacgt aatgcaggga
    28741 gccggccaat cccatctcct ctccggcgaa ggccacgaat cgcatgcggt atttgagatc
    28801 caggtctccc gcatcgaccg cctcttgcac caccctcgcc gtctccaata tcgcggccac
    28861 cccaccggag ttgtccacat aaccttcgct aagcaccgtg tcgtaatgag caccgaaaag
    28921 caccagcttg gtcgagctgc tcccaccgtt cacgtcggcg atcacgttct tgtgcgttcc
    28981 ctgggaaatg accgtcggca cgctcatgtt caccgagccg ccgtgcaaag ccgtctgaac
    29041 tagtaactga ccatcgctgt agttcaccga gccgacggga atgttgaggt tccagaagat
    29101 cggtcccatt tctcccagag gcaatccgcc gctcgaggac tgggagttct gctgggcgta
    29161 gctcatccag ggataattgt aatcatagat gatggcggcc ggaggctggg acagcaattt
    29221 gttcttgtaa acgccttccc acccactgga ccagcgaacc tccctcccga tgaggaggac
    29281 cttgccagtg atgttgatat tgctccaggc ctgccggtcg atgctcttct tacccacttc
    29341 accgtaattg ctcgccggag gcaatggaag cgtaaccagc tcgcccacca gaccattgga
    29401 tgacgtgggt ttgctgaagc tctcgcagtt gaaggagccg agcctaatgc catccgatgt
    29461 ggtaacattt ccatccatgt tgatggtgag cgatggttcg tctgcgaggt tccacaccgg
    29521 catggtgaag ttatccattg taacttggag accgtaggat gtgaactgtt cagctatgaa
    29581 atccgcagcc tcgttcgcgc ccggcgagcc gctgacccgg taggccaggt aattagagga
    29641 tatgttgctc agttcctcgg tgagagagat gatgttatct ccgttccagc tctgatccat
    29701 cagacggtcg gcgtccgagg tgtccacccc tgcggccatg gcccctggaa tcactaacaa
    29761 ggagggaacc atcaccaata gggcgatcag caacgctgtg aacttgcatc gcatgggcgg
    29821 gattttgaat gggaagtgag ctataaagca atattgagat gaaatataaa atagccaatt
    29881 ggaaaagagt aaagaaaaag tggacgggcc gggatttgaa cccggggctt cctgcttgca
    29941 aagcaggcga tcttccgagc tgatctaccc gcccagtgtt gccgcataaa agaagttcga
    30001 ataaaaaggt ttcgaggtca acggcagatg gctccggtgg acgccactcc gaccagacgg
    30061 cggtatttgg ccaatacccc ggtaggcttg cgatccacga ccaccacctt ggccaggcgc
    30121 tcctcgatct ccttctgcgg gaccagaagc tcgatcctgc ggccaggtat gtctatggat
    30181 atgcgatcac cattgtgaat tgccgcaatt ggccccttgt caaaggcttc cggtgacacg
    30241 tgaccgatgc acggtcccct ggtggcccct gagaaccgcc cgtcggttat cagcgccacg
    30301 ctgttggaca atcccattcc ggcgataaga ctggtcggag atagcatctc cggcattcct
    30361 ggaccgccct tgggcccttc atagcggatc acgaccacat caccggccac tatcttccgg
    30421 gcggatattg cctcgtatgc ctcctgctcg gaatcgaaca ccttggccgt gccttcgaaa
    30481 tgcatcatct ccggcgagac cgcggcctgc tttaccactg atcccagggg agccaggttg
    30541 ccatagagaa ccgcgatccc cccttcagcg tggaacggac ggtccatcgg gcgtatgacc
    30601 tcctggtcgt gaacgatggc ccgacgggcg atatccttga tgctcacgcc gttgaccgtc
    30661 atctcatcgg acagttcgga ccgtagacgg ttaagcatgg ccggaacgcc tcccgcagcg
    30721 tcaaagtcct tcatgtaata tggaccgctg ggcttgatgc tggtaagatg cggcaccctc
    30781 ttggatatct cgtcgaaggt gcgaagatcg acaccgaccc cgaagtcctg ggcgattgcc
    30841 gggacgtgca gggcggtgtt gctggaaccg ccgatggcca tgtccaggat gatggcgttg
    30901 gtgaacgaac cttttctaac cacctttctg gcggtcaggt tttccttgac catctccacg
    30961 atgcgccttc cggtcgcacg cgccagctcc ttttttcgag ggtccgtggc tagcatggaa
    31021 ccgcaaccgg tcagactgag cccgagcgct tccgtcaggc aggccatggt gttggccgtg
    31081 aaaagtccgg agcacgctcc ctgtccagga caggcgcatc tctcgatctc caggacctct
    31141 gcctcgctca tctttccagc cttgttcgcc ccaagcgcct cgaagacgct ctgcaggtcc
    31201 aggcctttat cgcccttgtg accgggttcc atgggcccgc cggtgagtat gatagtggga
    31261 atgtccagac gaccggcggc catcagcatt cccggggtga tcttgtcaca gttggtcacg
    31321 ccgacccatg catccatgca atgggcctgg accatgatct ccacgcaatc agcgatgaca
    31381 tccctggata ccagtgaata acgcatcccg gcatgaccca tggccacacc atcgcagacg
    31441 ccgggaacac cgaaggtaag aggtacccct cccgcctcga ttattccttt gcggacctcc
    31501 tcggccagct cgttcaggtg aatgtggccg gggacaacat cgttccagga gttggcgatg
    31561 cctatcaacg gcttctccat gtccgcatcg gttagtccgg tagctcgcaa cagactgcgc
    31621 tgaggggctc ggtcgacccc tttcttgacc gcatcgcttc gcatcggaat tggttatgtg
    31681 agaccggtta aattaagttc ttccctcagt cgtccccgaa ctcaatgcct tcctcggcga
    31741 agcgcagccg gagagcgtcc aagtaactgg ttactatctc atcacgcttc gagacatcac
    31801 gtatccagat cattatctcc actttgacct tctcccgttg gatgtccttg atcgagatag
    31861 atggtgcaaa aagtgacatg tccgtcttct tctccagata tctccttacg ctgctgagct
    31921 caaaggtctt gttcaccttc ttctgctctt ccgccccgac gtgggggagg atcaatgggt
    31981 ccttgtccgc tacgtccagg atcagatcct taatgcgttc gaagtccttg agcgaacgaa
    32041 gccacagtgg aatcctgatg gccacgatgc ccgcccggga gtagttgatg accttgttgt
    32101 taaccattac cgagttcggt acgtataata tccttccatc gaggtccttc agtaccgtgt
    32161 tcatgaggtt gatgtccttg accttaccga ttccagtagc cggaacaccg gatatttcca
    32221 cccattcatc gatctttacc ggcttggtga atgacatgag gatgccggag aaagcgttca
    32281 tgagcacctg ctgtgacgcc agggccacac caagacccag tatgcccaag gacgctaaaa
    32341 gggcggtcat gtccagccct agcacctccc agaaccccaa atagagaccg agagcgagaa
    32401 cggagtactg taacaacctc gctacggcct ttgattcagt tcgagagatc ctactgtcca
    32461 gaaatcttct ggccagcatg ttggtgccct tggccagagc gatcgtcacc agaactacga
    32521 ttatgaaccc tatcaggtcg gtcactgaca ggcctagcaa tgtgggttcc gccatcgttc
    32581 ttcatgatgg cccaccggtt tatattggtt gccattttag aggttagacg ctaacctgac
    32641 caaaacacca ttcataaata tttttttaaa aaaataaggt ttggaaaggg aagatgttgg
    32701 ttaagtgatt tacgttcagg acctgagaac aatttcgatg ttgaccccgt cagggacttg
    32761 gatcctcatc agttgcctca gggccctctc gtccgcgtcc aggtcgatga ggcgcttgtg
    32821 aatgcgcatc tcccacctgt cccaggtctc ggaaccttct ccgtccgggc tcttgcggca
    32881 gggcacctgt aacctcttgg tgggcagcgg aatcggtccg cgtatggcca caccagttcg
    32941 ggtggagatc tgctttatct gggtgcagac gctgtccacc ttttccgggt cggtgccgct
    33001 cagtgatatc cttgctctct gtgccatgtg tcaatcccct aaaaaaatga aagggaaagg
    33061 ggtttacatc tccttctttt cgacatcgat gcatatacca gcagccacgg tctggcccat
    33121 gtcgcggatg gcgaaccttc ccagctgagg gaagtccttg gccttctcga cgacgaacgg
    33181 cttggtgggc atgaccttga cgatggcgat gtcaccggtc ttcaggaagt gagggttctc
    33241 ctccttgacc tgtccggtct tggggtccaa cttcttcatg agctcgatga aggtacatgc
    33301 gacctgagcg gtgtggcagt ggaacaccgg ggtgtacccg accggtatgg cggtagggtg
    33361 gttcaggacg acgatctggg cagtgaaggt cttggccacg gtcggcgggt tgtccaccgg
    33421 tccggccaca tctcccctgt ggacgtcgtt cttggcgata cccctgacgt tgaacccgac
    33481 gttgtcgccg ggcctggcga tggggagtat ctcgtggtgc atttcgatgc tctttacctc
    33541 accgaccttg ttggagggca tgaagatgat cttcatgtcc ggcttcagga caccggtctc
    33601 gatacggccg acgggaacgg tcccgatgcc ggtgatggtg tagacatcct ggatgggcag
    33661 gcgcagggcc agaccctcgg tggatgcggg aaccttcagg ttgttcaggc actcgaagag
    33721 cgtcggtccc ttgtaccagg cggtgttggc gctcttgacc tttatgttgt cggccttgta
    33781 ggcgctgatg gggacgatcg ggatctcttc cagcttgaat ccgacggatt tgagcaggac
    33841 acccatctgt tccttcacct tgttgaactg agcctcatcg taggccggct tgacggcgtc
    33901 catcttgttg acggctatga tgatctgctt gacacccaag gtcttggcca ggaagacgtg
    33961 ctccctggtc tgggcctggg gcccctcgat ggcggagcac accactacgg cggcgtctgc
    34021 ctgggaggta ccagtgatca tgttcttgac gaagtcccgg tgaccggggg cgtcaatgac
    34081 ggtgaagtag tacttgtcag tgtcgaaccg cttgtgagag acgtcgatgg tcacaccgcg
    34141 ttccctctct tccttcaagc tgtccatgac ccatgcgaac tcgaaagttg cctttccctt
    34201 ctcttctgcc tgcttcttga acttctcgat cacataggga tcgatcgcgc cggactccaa
    34261 taggacccta ccgacggtgg tggactttcc gtgatcgacg tgacctatga atacgaggtt
    34321 catgtgaggt ttatcagcca tttgttttcc ctccagattt ttacttaaat actataggtt
    34381 ggttgcctct cgatattatt ctttctatat aaccgttttt catcttcagc cggagtaata
    34441 gcccgcgtca taaggctggg ggttcagtcc cttcctctta cggatctctc cgaccacttt
    34501 gtcctgcagt tccctaggca gtatcacgaa gcccgagttc tcggtcgacc aaagggcgcg
    34561 cccctgtgtc gctccgcgta tcgcgctggc gaaaccgaac atctcagcta ccggcgcctt
    34621 ggagattatc accgtggcgt catggtcctg atggatgtcc tcgatggtgg tccggcgtcc
    34681 ctgcagttcg cgagtgacgt cgcccatcat gtcctgcgga cagttgatgt agaccttctg
    34741 catgggctcc aacagtgacc tgccagccag gcacatcgca ccgtatatac cggaacgagt
    34801 tgccgggatg acctggccag gacccctgtg aatggagtcc tcatgcagct tggcgtcgac
    34861 gagcatgacc ttgaggccgg ccacgcgctc gttggccaat ggaccttgtt ccatggcctc
    34921 ctcgaatgcc tgcttgcaca gctccatggt ctcgtgaagg ttctggatac ctttggtggt
    34981 gtctatgaac acgttgttgt tcttgaaaca gacaacaccc ttggcctggt ccttgtccaa
    35041 tccgagatcg ctgagctgtt tggccagggc cttggggtcc tttatcttac cctcggtcct
    35101 gatctcgccg ctcttgatgg catcaacgat agcctgctcg agcggctcga cgatcatata
    35161 gaacttgtta tgcttgttag gggacttgcc ctcgaacggg cctcccctag ccctaaccgc
    35221 ctcgcggtat accacgatag gcgcggaaga tttgatatct accttatgat cgttcacaat
    35281 gcggtactgg gtaatctcca ggtggagctc tcccattccg gccagtagat tttccccggt
    35341 ctcctgattg atcgttatct ggatcgacgg gtcggcctta ccgacggacc tcagcacctc
    35401 gaccagcttg ggcaggtcct tcatgtgctt ggcctcgatg gccacggtga ccaccggttc
    35461 ggtgtagtga gatatcttct cgaagggctc catgtccttg tcggaggaac aggtcgcacc
    35521 agcgatggcg tccttcagac cggacaacgc tacgatgtta ccagcctcga cctcatcaac
    35581 ggcgatacgg tcggcgccga cgctcatcga gacggtctgg acacggttgg ggttgggcat
    35641 cccgaggatg tacatctcct gcccgcgaac gatcttcccg gagaacatac ggccgacggc
    35701 cacctcacca gcgtgagggt cgatgatgat cttggtgcac atgaaggtgg ttggaccctg
    35761 tcggtcgcag tgcatcatgg cctttccgac ctcagattgc tggtctccct tccatatgat
    35821 ggggatacgg atcttctgag cctcgaacgg gttgggaacg tgggtgatga ccatgtccag
    35881 gagcacctcg tgcaccgggg acttcttggc cagggtcttc tggtcctcgt tcttacagta
    35941 gttgtagacg tccttgaagg agatgccgct cttcttcatg tagggggcgg agatggccca
    36001 gttgttatag gcggagccga aggcgacgga gccgtcctcg accttgacct gccatttctt
    36061 gcggaggtcc tcggggaggt tggcattgat cctcttgttg acctcggcga tgatctggat
    36121 gaagcgctgt tgcatctcct gctcggtgac cttcagctcg ttgaccaggc gatcgacctt
    36181 gttgatgaaa agtaccggtc ggaccctttc cttgagagcc tggcgaatga cggtctcggt
    36241 ctggggcatg atgccctcga ccgcacagac caggacgatg caaccgtcca gagccctcat
    36301 ggccctggtg acgtccccac cgaagtcgac gtggccggga gtgtctatga ggttgatcaa
    36361 gtagtccttt ccatgatagg tgtgaaccat cgaggcgttg gccgcgttta tggtgatccc
    36421 acgggcctgc tcctgttcgt cgaagtccag cattagctgt ttgccagcca ggttctccga
    36481 catcataccg gccccggcga tgaggttatc gctcagggtg gtctttccgt ggtcgatgtg
    36541 cgcggcggta ccgatgttcc tgatgaactc aggagtcatc atgatgtcct gagccttctt
    36601 gatgttgtcc tcttttctgc ccatgttccc cacctggttt aacgagctga tgaagcgacc
    36661 ctttcgatct cttccttctt ggccacggag aagctgttca tatcgccctt ggaggcgagg
    36721 atgagctcct cagcaaggca ttgctcgatg ggcttggtgt tcttgaacga ggcgttgacc
    36781 gagcccttgg atatgtttcg cagagcgatg tccagcctgc gggagggagc cacgtccacg
    36841 gccttcggga cggatattcc tccgaactgc aggcgggtga tctcttcccg gggagcggca
    36901 ttctcaagag cctcgaccag aacctggata gggttcttct tggtgcgctg ctcgatgatc
    36961 tcgaaggcct tcttggttac gttgtaggcc ttcagcttct tgccggtgta cacctcggtc
    37021 ctcatcatgt tgttgatcag gcgctcgacg atgttgacct tggacttccc gaaccacttg
    37081 ttggcatgcc gggcagtggt gtggggcacg gcggtggggg tcaagttgat gtacttggcc
    37141 agacccccgt ccttcaccac gacctcgccg ctggcgtact tgccgaaaag catgatgtta
    37201 tcgaatttga aactgctctc ttccacagaa atcacctaac cggcttctcc ttcctccccc
    37261 taaccagttc gttcagggag acgttgttca cctggatgac cttgaatcgg accccgggga
    37321 tatcaccgta ggaacgaccc atccttccac cgatgccctc cactaggacc tcatcatgtt
    37381 catcgatgaa gttgatcgcg ccgtcgccga ccgcgaatgc ggttatctgg cggccgttct
    37441 tgatcaactg gaccttgaca cattttctga tggcggagtt aggctgcttg gcctcgatgc
    37501 cgaccttctc cagcacgatg ccttttgcct gagctgcacc ctcgagcgga tcggaccttt
    37561 ccctgagctt caacagtctt ctcttgtaag acctgtcgct ccacctggac ttctgccgat
    37621 cgttcctcag ctttctggca gtgaataaac ctttagccaa atatttcacc tctaatacag
    37681 gagcatcgca cctattaccg attttgtata taagaatatg ggattatgga cggcggcgaa
    37741 aacacaatac tggacggtat agggggcttg cggtttgcat atgctcttac cctaggaaat
    37801 gtaggatgtt tcaggcgtct tccggtcggg aggatggggt ctcagaaccc gcacgaggcg
    37861 accggcgccg tcgtatccgt acaccatgta gtagaacagc caccagttat taagctcaag
    37921 cattctgtag cgaacctgca tagcctccga tcgaggggcc atgaccacca acctgatctt
    37981 cttcctcaat acatcacggt aagcgatgag ccggccctcg tccttccacg aatcggcggt
    38041 ctcgatgatc tcatgaccga tcagggcgcc ctgatagaaa atatcgatag acccgcgtcc
    38101 aacctcgtca atcgaaaaat gagtggctat gtcaggatga gggagctctt cctgtatctc
    38161 ctgcagacgc ctcttggcca ccttgaacac caggtcgtcg ctcacgcagg gatatgagga
    38221 ggctcgtgaa gataatgatt ttcagatgct cacgccctac cgcgggactc accgcgcacc
    38281 agggcggtgg cgatcagatg ggccagccgg accggttccg gtaggcaccc ccttacgatg
    38341 cactggcgga ccatggcgtc ggcctccttc tccccgatcc cttccgaggt cacatagacg
    38401 cggccgtcgg gcacctccaa aggacgcacc cggttgcgcg agatcacctc gaaccgccgc
    38461 tcccaatcgg gaaaatgcgc cctcagcgca tcaatgatct ccgtcaagtt cggttcgtcc
    38521 cgagagatgg tcagcaccgg aactccgatc tcctcgctga gcgctcggac gtccaccacg
    38581 ttgaatcccc ccagtgccgc gccgtccacc atgaccatgc gcacctgttc ggaaaagcgg
    38641 gaatccttga ccatgctgga tatcgcttcg ttggcgtcat cgccgtccac ctggcatgac
    38701 gatatcatga ccccctccac gtaacctgga ggacggacca ggaccccggc caattgggca
    38761 cgtgcctggc ctttttcgaa tggcccgtcg tcgatgccga ggacgcgagc ctggtccttc
    38821 acctacatca gccccaggtg cccggtcacc cggtccacct cggcgttggg tgccggaccg
    38881 atgcccaggc aggtggtggt gttcggaggc agctcggtca tcccggcgtc ggtgattaga
    38941 gaggtgacca gaccgaggtc ctcggcggcc tgtttgatct tgtaaagctc cgccaggtcc
    39001 tggaccttga ctaccacctt cttttgcccc tcgttgtacc agcggtcgaa gttgatgggc
    39061 ttgcgcttct tgctggcgaa agcacagttg accgcggcgt gggccacctg agcggccatc
    39121 ttgccggggg atatcttgag gtccttgcgg accacgatca ccatcttgag ctcgaaatcc
    39181 atataaggtt cacacatccc cgaaggccag tgggaactgc cggcgaagaa ctcgctcctg
    39241 attcttctcg gccagttcga tcttcttttc cgcttcttca gcggtgaact tgatgatgat
    39301 ggtcttcccg cagatggggc aggggaactc ccggccgtcg atgcagtcct ggaccagcac
    39361 ggtgatcagg atctcacatt tcgggcagca catcacaaag gattccatga tattcgttta
    39421 gcccatttcc tgccgcggat atatcccttt gccgccgaga gcggatatta cctttaatat
    39481 aacgagagga aatgaggcgc ctatgttaga gctagtcaaa cgcgacgggt tggcccgcat
    39541 atgccggctg catacccgcc aaggtgagct ggagaccccc tgccttctgc cggtcatcaa
    39601 tccccggctc atcactataa gcccgaggga gctgtacgat gtgttcggtt tccgggccct
    39661 catcaccaat tcatacatca tccgtagcga tcccaagatc agagaggacg ccctgagcaa
    39721 ggggctgcac gagctgcttg atttcccagg ggtcatcatg accgactccg gcaccttcca
    39781 atcgcacatg tacggtgagg tcgacctcat caacaaggag atcgtggagt tccagaggga
    39841 tatcggttcg gacatcggaa cggtgctgga catcttcgcc gaaccggact ggagcaagga
    39901 gcgcaccgcc caatccatcg aggtcaccct ggaaaggact atggaggcgg ccgagctcaa
    39961 gggagagatg cttctggccg gggtggtgca gggttcgata tacccggacc tgcgggagat
    40021 gtgcgccagg cggctctcgg agatgggagt ggacgtgaac ccggtcggag gcgtcgttcc
    40081 cttaatggaa acataccgct tcgccgaact ggttgatgta atcatcgccg ccaagaaggg
    40141 gctgcggccc gataggcccg tgcatctctt tggcgccggc cacccgatgc ttttcgcctt
    40201 ggcggtgctg ctcggctgcg acatgttcga ctcggcctcc tacgccaagt tcgcccggga
    40261 cgaccgcttc atgttcctgg agggaacgtt caggttggcg gacatgaagg ccctggaatg
    40321 caactgcccg gcctgccacg gccacgatct ggaggagatc aaagcgctcc caccggccaa
    40381 gcggacggcc cttatcgcca ggcacaacct ctgggtttcc aagatggaac tggaaagggt
    40441 aaagcgagcg ataatggagg gggacctgtg ggaactggtg gagaggcgct gccgctcgca
    40501 cccggcccta ctggatgcgc tgcgagcatt gggcaagcac caggagttcc tggagaggta
    40561 cgagccgctg tccagggagc atgccctgtt ctataccggc ccggagacgc tgaaccgacc
    40621 ggcgttcctg agattccaca agcgatcgac cgaaaggtac gaacaccctg cgaccgaggt
    40681 gggaatggtc ttcgaggaac cggagaaacc atactcaagg acgttgcgtt cggccatgga
    40741 ctcgatactg gagataagcg atgcgcactt ccacgtcata tcgcccttcg gacccgtccc
    40801 catcgagctc gatgagatct acccgatctc ccagtcacta tttccaaaga accaggacca
    40861 acagaccgtg gagcgcacca aggagctgat ggaggaattg ggacacaccc acagctacaa
    40921 gatgggcgcc atctgggatg gcgacgagac gttggagttc ctgaagatgt tctctcaggg
    40981 gaagggcacc tttgacatag atatggcaag agtgcgggcc gtggccgact accagttcgg
    41041 aaaaggcgct gccgacgccc tcctttccgg gaacgtcagc ctggtcaagt cgaagaacgt
    41101 ggaccgcatc cgaaacgtgc tggtggacgg cgagcacgtt ttttcgatga gggccgagga
    41161 tggtttcctg accctacgac cggccggggc caggagattg ctcaagggca ttccggcacc
    41221 aaggatgcga gtgacgattc aggacgacgc ggtggagttc aacaagcagg gtaagaacgt
    41281 tttctgctcc ttcgtgaccg acgccgaccc cgagatccgt ctgcacgatg aggtcatggt
    41341 ggtggacaag gatgacaacc tggtcgcgat agggcgggcg cagctcaccc gcgaggagat
    41401 gctgtgcttc aagaagggag tggccgtcaa ggttcgtgag ggcgcctagt cctcgacgtc
    41461 cgtgatctcc tcggccacct tcaggcaggc catgaggtcc tcgatggtgt ggagcaagga
    41521 catcaggccc ttggcctggc actccacctt gagaacggaa ccttcaaccc aggacctggc
    41581 gtgatcgccg ttgtccagct ccaatgatct gttgacgtta cgggcgcgtt cctcgcttcc
    41641 caggtctagt tccagaaggc agctcgcttc cacggaccgc tcatgctcga gaggggataa
    41701 aatccctttg ctgtatcgat ataagagaga tggtagcccc gtccagattc gaactggagt
    41761 caccggctcc aaaggccagc atgattgacc actacactac ggggctctag ttgacctcga
    41821 tgcgatatcc cctatttaat tttccatccc tgggacggta gttccgtaga tgtgcgcgga
    41881 ggttcctcct gcgatcatcg ctgcgggcta tgacgcggtt cccctgccct ctttcatcga
    41941 tgaggacgta gttcgctcgg tcgataccta tggttcaggg cgcacccgtt agtctcgacc
    42001 aggaacttta cggggaccga tgggccaccg atttactata gatagttcga atgacttttg
    42061 gtcgatcgcg catgcttctt gacatccttt acctcctggg cgggctggtg ctacttatca
    42121 tcggagctga tcgcctggtc aaaggagcgt ccgctctggc ggcgtccttg ggtgtcagca
    42181 ccttcattat aggacttacc gtggtggcca tgggcacttc cgccccggag gccaccctgg
    42241 ccgtgatctc cagtttggag ggagacccgt ccatatcctt cgggaacgtg ataggggcca
    42301 atattgtcaa catcggagtg gtgctagcca cggcctgcat gatctgtccg atagcatctg
    42361 agatgaccct gctcagaaga gaggcggtgt tcctgataat atcgatattg gccgtcgcca
    42421 tcctgggtta caacggcgtc atcgacctga gcagcgccct cgtcctgatc gcggccgcgg
    42481 tggctttcaa tctattcgtg ctgaggtcgg caaagggaga aaaggcagca aaaaggatag
    42541 agccggtgga agaacgtcct acgatggaaa agtggcgcat gctggtcttc attgttggcg
    42601 gtctggcgct cctgatattc ggctctgagc tagtaatgcg tggcggggta ggacttgcca
    42661 cggacctggg agtggacgag ttcaccatag gactcaccat cgtggccatc ggaaccacca
    42721 tgcctgagat ggccgtctcc atatcttccg cctgccgact cgagaccaac atgcttctcg
    42781 gcaacgtcct cggaagtaac atattcaaca gcctgctgat aattgggctg gccggactgt
    42841 tctcccccat tgccgtccca ggcgatttct acaccctggc attgccggtc accctggtca
    42901 tgtacgcggc cctggtctcc ttcatgttca tgaagaggaa gctaaaccgc accacgggcg
    42961 ccatattgat ggccatatac attgggtacc tggcgctact attgatctga tgttatcgcc
    43021 gatcgaacct tgaaggaccg ggatgcgaag cgattcagga ggtgttcttc ttctgttccg
    43081 cctcgtacat ggcatcgatc atggccccga agaaacaaca tggtttatac tccccctcgg
    43141 gagcccctgc cgctttctcg ttggcgccca tcaacgatac gttcggatgg ccgtccatga
    43201 gcaccttgag caaccacacc ttgtcctctt cattctcata atgcagcgag ccgatctcct
    43261 tctccccatc catatccacc ttggccaggt gaatgtgccc gccctgggcc tcgttcttta
    43321 ccgtgagagt gatgagcatg ttttcacctg gtgatggggc cgcgctgcgg ccacttgtaa
    43381 tagttgtcga cgaagcaacc agtggggttg tccttctcca tgaaactgat ctcaggatga
    43441 cctttcatta gcatgtccaa cagtacgtcc ctttcatcct tgttttcgta tttcagagtt
    43501 ccaagtatgt gggtgcaggt tatggaaccc cgtttccaaa gttcgagcgt accgcttccg
    43561 tcctcgttct ccaggacctt catattgatg tatagagcca tgggatcgac cagataagct
    43621 acttctttcc agcgactgaa acttcgtatt agctatatgt caattgtgag aggatttcag
    43681 taatggaact cagaacttat cagatcgctc aatgtagacc actgttcctg ccgatgatgg
    43741 tgatctcacc tatgagcgga gaatcgagat ttgttccgta atagaaagag atggcgcgaa
    43801 gggggggaca catccctatt gatagccagt catgtcaaat ttactttcaa tcagagggtt
    43861 tttgtctttt agggggtacg atgacgatac atcatcctcc caaagtttgt tgagggtcat
    43921 cagcgcttga ccgttcttga tacgtccgta ggtggtctcg gtggtcttgg tggtcgagtg
    43981 acctgccgcc attgagaccg cagcggtctt gctagggtcc ttgtcgatgt tcatctgaac
    44041 gaacgtgtcc ctcatggtct tgagttggaa ctcaatcctt gagccctcga ggtccatgtt
    44101 gattccttcc atgaagccct tcttcatgtt cctgaaggcg ttggagcaat agaagcccgc
    44161 agtgccgtca ctgtgccttg ccggtatcag cgcgtcgcat tccgtaattc ctaatcgctt
    44221 caaccgttgc tctctcgcat tcaagaagcg gaataccgcc ttccttgcag gtggtaggac
    44281 cggtgcggtc cgctttctgg cgtacctatc ctcccccttg ggatgcctga cgtatattga
    44341 ccaatcatgg gtgttgaggt cttcaagatg agataacctc agctcggaag ccctcaaccc
    44401 ggtgtatgga tacatgtaca tcaggaatct gcacacctcc ccttcccagc cttttagaag
    44461 gtcggccttg cccaagatga gctttaattc accctcgctc aaggagtgaa ggtcctttgg
    44521 tgtcttcttg ggcaactcct caccactggt ctttattcgg gcgaaaactg gatttcccgc
    44581 gaaatcgcat acctgcttca ggaatcccag gttcttcgcc atgtatgagc cttcttgccc
    44641 ttttgaccgc atccatagga tgtaggcaga tatgtccgcc tcggtcatct tctcggggtt
    44701 ggtcgtgctg attattttgg cctcatgcag cgctatga
//
LOCUS       DAOPZI010000008        44602 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_701_length_44602_cov_10.967764, whole genome shotgun sequence.
ACCESSION   DAOPZI010000008 DAOPZI010000000
VERSION     DAOPZI010000008.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 44602)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 44602)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44602
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_701_length_44602_cov_10.967764"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..2743
                     /locus_tag="PKM11_02865"
     CDS             <1..2743
                     /locus_tag="PKM11_02865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47484.1"
                     /translation="VPKGDISLYATATVNGQEVVFLEKVIATDSAVIDLVLTGGMVLS
                     GTVQYSSAAVSGADVVLQDRSGGATLTAVTNSQGKFRAVLPSGLYFTYINDGTRAYWG
                     DVNVVSSMSMTFQLLTSVKVSGKAWYDADGNDAASAAEGLNGAVITVTDQDGRSVNMG
                     TSPTGQYSFVLVSGRTYALTAVKDGFQTLARNYPSISLSVTDDLEMVALQRTVTGSVS
                     MDFPGDKGNLTVKFVAVSGPAMDNQTVTNADGTFSAMLYPGKYIVLVNQNVTAGDPSV
                     RYQSLSDQDLEVLVGSDPSSLQIELVKRSLVSGAVSPSGTAKLVFDGPDKVSVTAGQT
                     YSLYLQDGSYNLYATVSNGSRNYAALSRVNVTGATPLNITTSDAAPAIIQATMSGARA
                     QSIVISIELAGAYYNVTTPDNGQASVYLPVGSYVASVEHSTILTTASQSRFVKYVGEQ
                     DFTMSGSRRNVAISTVMSYENATVSGIVTADGSAATAQIEFQAMSATAQDLTVSAVGS
                     YAVGLSPGNYTVYAINQDSSRAYLGKLSITDLDDVTYDIVLVEAFRLSGVTFAQNDGV
                     SSEVSVNGMISMTSSSDGAYEIYLPGGSYTLYAETALLENGLLVDYQGSASVSLSDVT
                     SKGIYMQRVAKQKVSLTWDPAQKVTLNAGETATYTIRIVNDGNLQDTFRLTSTATGWT
                     VVLSQTEVTLGYGASNSQTVTVQLTPSASVLVKHTAVIVRAVSITNSSAAASVSLDAV
                     IAPARAVSMAYQGGDSTKGDEYVHTVAVTNAGNVDDTYAISIGNQQALRDLGWEVRLV
                     NKTALADSLSVTVAASKSSEIEVSMVPLRSNPSPTVTVQLVTTSSADQAVRSSLDVEP
                     QFVGLDGNGLTVTGVNVEDSTPTLGQGSIVLLGLALALMAVLIVLSMQKGVFSRRKR"
     gene            2743..3513
                     /locus_tag="PKM11_02870"
     CDS             2743..3513
                     /locus_tag="PKM11_02870"
                     /inference="COORDINATES: protein motif:HMM:NF019325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CARDB domain-containing protein"
                     /protein_id="HNX47485.1"
                     /translation="MLIMAALLLLTVMPIAQADTYDPLYAQIDGPRVVATNSVTMYTL
                     VMFGGPAEVGVGNYTYKATMTGSGNTYGASFIPGTVQPSPDGTFYINLTAPAGPQTLS
                     IHIECMSIGLSQTVKTTIDLQVKVVEPISLRSTIKNTGEVAAVGVPISLQLYQDGQWV
                     EFHRTTVDLAAGQSYQFKYNWTATDLASGEHKVRMVLDPNNDIVTFEGGSSVYETTIY
                     YKMPGYDWVNTLLWVLVVALGVTIFFVWRRPAKGKKKR"
     gene            complement(3523..4140)
                     /locus_tag="PKM11_02875"
     CDS             complement(3523..4140)
                     /locus_tag="PKM11_02875"
                     /inference="COORDINATES: protein motif:HMM:NF014099.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47486.1"
                     /translation="MQNLEHIAQRIQDSLEEKDTVREIAIKSSRAIIRMSSGVVHGMH
                     KGVDGEAALAEAIDEAHKLKSVLSEHVEIWYSGIVQDALVEVAEAAILNALVKGQELP
                     DPEHLGMPGTSYLLGMADTIGELRRFSLESLRRGSISEAERYLDLMEELFLVIMSFDY
                     PDAIVSIRRKQDIARSVLEKTRGDVSLAVMSERLHGRMGDLEKRL"
     gene            complement(4175..5497)
                     /gene="purD"
                     /locus_tag="PKM11_02880"
     CDS             complement(4175..5497)
                     /gene="purD"
                     /locus_tag="PKM11_02880"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HNX47487.1"
                     /translation="MTAKVLVVGGGGREHAIVEALIRDGATVYVAMKNHNPGIARSAQ
                     EFKLLKETDVAKVAEFASSCGAEIAVIGPEAPLEVGLADELLKRGIGCVGPSQAAARL
                     ETSKRFSRRLLKKHNIPGNVAFGTFQDYDSAKLFVDDFPGELVVKPEGLTGGKGVKVE
                     GEHLEGKSGVLAYVKEVLEHKIGGAGVVLEERLVGEEFTLQAFCDGRNVRGMPLVQDH
                     KRAYDGDVGPNTGGMGSYTDADHLLPFVTDAERQKALEIMQRTIDAMREDGSPYRGVL
                     YGQFMLTKDGPKVIEFNARFGDPEAMNVLTLLQNGFLDVCQGVADGKLSKQVPFLKKA
                     TVCKYVVPAGYGTESKAGRPVMVNERKLADTGARLYYAAVDEKDGMVLTTSSRTLGVV
                     GMADSIEEAEAICEDGLKHVQGEIFVRHDIGKRELVRRRVEHMQQVRN"
     gene            complement(5541..6167)
                     /gene="hypB"
                     /locus_tag="PKM11_02885"
     CDS             complement(5541..6167)
                     /gene="hypB"
                     /locus_tag="PKM11_02885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HNX47488.1"
                     /translation="METDVLAENKHLADHNHENLRSKGIRSLDIMGSIGSGKTALIIR
                     LAKEMKKKGINVAVIAGDVTGQDDFNRFQEAGIKAFNINTGKECHLDSLMVDKALDHM
                     DLEGVGFLFIENVGNLVCPADFPLGTDKRMVVISVTEGDDMVRKHPMIFQGADVGVIN
                     KMDLAEYMGIDIARVKADYRKLSGGRELLTVSERTGEGLEALVEALLV"
     gene            6510..11426
                     /locus_tag="PKM11_02890"
     CDS             6510..11426
                     /locus_tag="PKM11_02890"
                     /inference="COORDINATES: protein motif:HMM:NF024627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HNX47489.1"
                     /translation="MLLVCAAFLIIGAPNASAAGPTYEYGDITTNTAWTEAGSPYIVN
                     DTITVNVGATLTIGPNVTVMVQPGNMIIVKGTIVADGTAALPITFTTNDTVTFVRWNG
                     IEIQYTSTGSLFDNVFIDKAGGNAGITVLNATVGMTYVTVNNSYSGVDYQFENKAVSI
                     SVDNCNFTHMDYFGVRINGYAWAVDSNVTDITVPISITNSIFDGNGYGVDIWWLEANA
                     QDNATAKMTCDISILNNTFEGSNSAAIYYDLNVDISENGTVVIAGDILIKGNTIKTSN
                     YGFEKENDNDIRAEDTSDVMISGDISIVNNTFEDLVDDAIYLNTQVEYVYDEATVSIL
                     GDISISGNTFEDIGGSAIYCEKYIGWNSYVYDDAEATISGGISVVDNTIKNVDYGLYY
                     QLYIDTDDNGTGSISGDVTVTGNYFESCGDDGIYVEKEGGSRDENSTTNMDVSSYVNN
                     NQFWNCSSDAFYEYTYFESDGYGAISISGETIFSENVIRNIDRYVMEVERELYSYDLS
                     ELSSDCPYSMINNDVVIADELIDIYPYYYAYDESVMNITNENVVITGNTARQLYDYSL
                     YAYLYYESYDDASLNVSGKIDFIDNDVNCLYDESAYIERYMDVRDDAIFNVLYPITIQ
                     DNVISVDDGDDYYAIYVYDVLDAYSSFNNTATISGDVTIENNQISIISGDGIYLYVDI
                     DVETDDDYTSAIANYDVNYVIQDNEITVFNDNAWDYTYGIYAYLGCYLESDGDMGAAS
                     LTVGDVLIEGNTVSMSGESYLYGIYLYIYAESYSYGGDATLVLSEFSVTENTISLDTY
                     DGYGIYLYYPYFYVYADNGNATLTLDSINVVGNSIDTLGDSIYGIYVYEPDFECYVYG
                     GDWWYLNTATLEATNGFNIDDNTISMVGDYTYALYLEYVYRYVYSDDYWSQATVNVPI
                     SISGNSIVQTGLASYGIYLYYVDYDVYYDYSYATLIAPMEISDNTVEYIENDDYAYGL
                     DVESIYLDLADPTYIGEYVLDIPIVISNNVVVAGYDGIYIYDSTDGVQVFVTGNTVSE
                     TTDYGLYVDDVEYLYVEDNVFSNNMGDGAYVEYLVNSVIGNNTFSENGEYGLYVDYGC
                     EYLTIYNGVYDDNSYMGIYIYGGKGVYWVVDAASEIVNNDAEIYAHVEVRAGGVLTID
                     SVQSFLLGDGYDGVTLLKVLEGGKLIVGNSWLESDDGDGRFLIHGDLDMSNTWLTQWS
                     ELYLGPTATGSISASYISDNDKNGIHIDGCSPRISLNTISGNYMDGIFIEGASASPRI
                     TNNLITENSRGISARGCDLNQVIGNIFVGNDVAGLYAQNVTGAIHGNTFLMNRIEIYV
                     KDSDVSIQSNEIGYARMIGALAKFGPVSQLLNNMSGNIVSGLMSTYLEVSSESMFNHM
                     GIFAESSTVKASGNTYGMLYYAFYAEDSTVTFSDDLTSNKIVLSLLNANLEQVNISVP
                     TYLFNGIYASNSAVEIKDSRIECMETAVFLDTCTGSITNCELVAERFDVYLTGDCDVS
                     LSGTTLDGELKVEGSSTLMVYNWLDVITKNDDNETMSGVTVEIKDSAGTLISKGKSDD
                     NGVYRASVLAYTVTSEGKNYTDAYKVTADFDNGKVSKKVTLGDSSVTELTIEANKDNT
                     VLYVSIVFIIVVILLIVVVMVMRRKKKA"
     gene            11522..12820
                     /gene="gatD"
                     /locus_tag="PKM11_02895"
     CDS             11522..12820
                     /gene="gatD"
                     /locus_tag="PKM11_02895"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu-tRNA(Gln) amidotransferase subunit GatD"
                     /protein_id="HNX47490.1"
                     /translation="MSYSEFVMTSLETAGAEEGDTLEIVSGKRSYKGVLMPHHEFSHP
                     DVIVIKMKSGYNIGVKLSAGSKVSVIEKREAKMKPARPQRSDDNLKTIAVIGTGGTIA
                     SYVDYRTGAVHPALSADDMVGAVPEISSICNVKARVLFSIFSENMDPECWVAIAKAVK
                     EELSNGADAVIIPHGTDTMGYTSAALSFMLDGLDKPVVLVGAQRSSDRPSSDSYTNLI
                     AAARFCIETSMPGVFVLMHETLSDTTAVVHKGTRVRKMHTSRRDAFKSINSSPVARIN
                     FEGKIEMLCDETPKPAASLVVKDVLERKVALLQFHPSMDVELFKELMLKHRGIVIAGS
                     GLGHVSTPMVKALSEVVKAGTAVIMTSQCLSGSVNLNVYATGRDLINAGVVPVGDMLP
                     ETALVKLMWVLGQTSDMKEAARMMTENLRGEISQRREIDG"
     gene            12813..14675
                     /gene="gatE"
                     /locus_tag="PKM11_02900"
     CDS             12813..14675
                     /gene="gatE"
                     /locus_tag="PKM11_02900"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu-tRNA(Gln) amidotransferase subunit GatE"
                     /protein_id="HNX47491.1"
                     /translation="MAERVTCGIEIHQQLNTNKLFCSCPCDLIEEEGATILRKLRPSQ
                     SELGEIDRAVLAQAARKMSFRYQSPRSRCCLVEADEEPPHDANVNAMQATLIVSEMMG
                     CRAVDEVHFMRKIVIDGSNTGGFQRTALVAIDGDIEINGKKIAIQTVCLEEDAARKVE
                     TKGSEITYRLDRLGIPLIEVATGPDMHDPEEVREVAVRIGSILRATKMVKRGLGTIRE
                     DLNVSIPGGARVEIKGAQDLKLLPTYVEREIERQSGLLKIRDELVARGVTKVEPDIID
                     CSDVLKGCRSKVISSALSKGGKVFGVALAGFEGLMKSPDSKLRLGSEMAQYAKTKGVA
                     GIFHTDELPGYGITQEEVDALRDKLGLAPGKAFAICADERTKASSALKMAADRAYSAL
                     NGVPEETRDPLPDGGSAYSRPLPGAGRMYPETDVRPITIGVERLEAIRSSLPELPGAK
                     AARFVKAYGIHEQQARQIVKEGYEDLFEDLAERYGMAAIAARTFLNTLPELEKEGVDT
                     SKIGDGEIVEAFASLSKGEFAKEALPAVLKELAKGSNVKKAVSSLGIGSMDQGDAANI
                     IDAIIEERADFVREKGEGAVGPLMGVAMQELRGKVDGKKAADLLRERVQAFLRG"
     gene            complement(14665..15231)
                     /locus_tag="PKM11_02905"
     CDS             complement(14665..15231)
                     /locus_tag="PKM11_02905"
                     /inference="COORDINATES: protein motif:HMM:NF011529.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HNX47492.1"
                     /translation="MLRDRSLQLYVHPDVYAPAEDTFLLLSAIDVEKGEKALEMGCGS
                     GIVSLHMAKAGTKVTAVDIDERAIEALENSAMMNGLYIQAVQSDLFTDVEGRFDLIVF
                     NPPYLRGDVQGQEDLCWAGGEDGVQLTSRFLKEAKEHLEPDGRVLLLVSDDMDPSALD
                     EALSEWKVRTVACKTLFFEELRVLTLTL"
     gene            15303..16199
                     /locus_tag="PKM11_02910"
     CDS             15303..16199
                     /locus_tag="PKM11_02910"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013827.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HNX47493.1"
                     /translation="MDLYSLVAIGLILGGLLLAYLKRYPLAQMLVLINLAIFLLCTIA
                     SWDSFSFLSAVQRDLGFRPDYVDQPSHWFTAFTHMFVHADLLHVLFNMIFLVLIGVPL
                     EERIGRRNFALCFFIPGLLALLLESAVRVSDPEILILGASGAVAGAMGALLFLYPKDE
                     IPMFLGFIFLPRVPVWISVGAWFALQAVSAFTLPSGIASGGIAYAAHIGGFVAGMGVA
                     FLLPSEGEDVPDDVVDLGDLAITDELRNIKERIETETEPDVRRAWLERFVERSVCPEC
                     GARPRLEGNRIKCTCGWQRSVR"
     gene            16196..16789
                     /locus_tag="PKM11_02915"
     CDS             16196..16789
                     /locus_tag="PKM11_02915"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47494.1"
                     /translation="MSANRVEVLCPGMIVRDGPAVLEARSTVTLVSRGDRRLLVDTSA
                     PENRKMLTEALRSRELAPSDIEMVVLTHAHGDHQGNLSLFPQAKIVAHRAEGGELDLE
                     GEVIIWEGVRLVNTPGHTPGSISVLVKAEKTYAIAGDAIPTEDNARKWVPPGHHYDRR
                     KAMGSMEMLIEAADVVVPGHGPAFRTAPYKEKGRRGE"
     gene            16786..17385
                     /locus_tag="PKM11_02920"
     CDS             16786..17385
                     /locus_tag="PKM11_02920"
                     /inference="COORDINATES: protein motif:HMM:NF039705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HVO_0476 family zinc finger protein"
                     /protein_id="HNX47495.1"
                     /translation="MNVPNAIQVECPDCGEETLHEVLKGRLGKDGNTLEGTLRCQDCG
                     RVHTAVIRETRTVMVPVIISDQGESRKAQIEIPEDEVIRIEDELILDDLPIIVSSVEK
                     GDGRVVKALAKDITTIWAKRFDQVHVKISINDVHKTIPAEIVVLPEEEFFIGDLMTVG
                     RYNVVITQIKTSDGMARRGSVLARDIVRLYARKARITYA"
     gene            17385..18035
                     /locus_tag="PKM11_02925"
     CDS             17385..18035
                     /locus_tag="PKM11_02925"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HNX47496.1"
                     /translation="MGMDERRQMVAVLRGRGLTFSKRVEEALLSVPRHIFLPESARAL
                     AYRDTPLPIGDGQTISAPHMVAIMAEALELRKGQTVLEIGAGSGYNAAVMAELVGPQG
                     KVITIERHPSLAERAAKTILEAGYANVQVVVGDGSLGLPEQAPYDRISVTCGAPRVPL
                     PLLDQLRDGGIMLIPVGNLEYQSLLRVRKLGGRTIAEDLGSVVFVPLIGEKGHPSQ"
     gene            complement(18027..18683)
                     /locus_tag="PKM11_02930"
     CDS             complement(18027..18683)
                     /locus_tag="PKM11_02930"
                     /inference="COORDINATES: protein motif:HMM:TIGR01488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HNX47497.1"
                     /translation="MSENGRKFDLVAFDMDGVLVDYLSSWTWVHDRFGVSNEESVISF
                     MDGDIDDMEFMRRDIALWLKHRPGLNLKDVERELLRLPINPGIGATVQALRERGTKVV
                     IISGGLDLIAEKIAKEHGFDAQWSNGLEADAHGTLTGEGVLRVELCNKRRSLREAQEM
                     FGVTPERTAAIGNSSIDVSMFQTASLGIAFNPIDEEVIQGAHHVVRDASLSAVLPFLL
                     "
     gene            18736..19437
                     /locus_tag="PKM11_02935"
     CDS             18736..19437
                     /locus_tag="PKM11_02935"
                     /inference="COORDINATES: protein motif:HMM:NF014066.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HNX47498.1"
                     /translation="MIVLVGVAHVIDVSKPIGSLVEHYAPGAVGIELDPGRYRALKEG
                     SPRGKVPIPYRLLAVMQRRLADQFGGEVGAEMLAAVDAANARGAQVLFIDMEAGRLFN
                     SLISQMPLKERVALLLSSFGGLFMTRKRVEKELQEFQDNEERYMETLGKSFPTVKRVL
                     IDERNEHMARNILRAEGQYGSVLAVIGDGHVEGIRRILSREDLVAYRLKDLNDLRLER
                     PVSNAEASFSFTIGN"
     gene            19475..20149
                     /gene="thyX"
                     /locus_tag="PKM11_02940"
     CDS             19475..20149
                     /gene="thyX"
                     /locus_tag="PKM11_02940"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HNX47499.1"
                     /translation="MKVVLLSYTNDAERLCAAAARSCYSPDAASEILEGVEEDKAGAF
                     IDKVVGMGHHSVIEHASYTFSLEGVSRSLTHQLVRHRIASYSQQSQRYVSLLEPDYVT
                     PETIRADPKLNKMFEEAMEKAWEAYQKLATVVPVEDARYVLPNACTTNIVVTMNAREL
                     WHFFTLRTCRRAQQEIRTVAELMLTEARKASPTIFRDAGPACLRGKCPEGKLSCGKPR
                     TELRFK"
     gene            20188..20379
                     /locus_tag="PKM11_02945"
     CDS             20188..20379
                     /locus_tag="PKM11_02945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17e"
                     /protein_id="HNX47500.1"
                     /translation="MGNIRPTYIKRVAVELVEKYPRAFSADFENNKILVQRLTNVSSI
                     MMRNRIAGYVSRYWQNKDF"
     gene            20560..20633
                     /locus_tag="PKM11_02950"
     tRNA            20560..20633
                     /locus_tag="PKM11_02950"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20595..20597,aa:Arg,seq:gcg)
     gene            complement(20643..22556)
                     /gene="rqcH"
                     /locus_tag="PKM11_02955"
     CDS             complement(20643..22556)
                     /gene="rqcH"
                     /locus_tag="PKM11_02955"
                     /inference="COORDINATES: protein motif:HMM:NF041120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome rescue protein RqcH"
                     /protein_id="HNX47501.1"
                     /translation="MKKEMTAFDVAAITSEMQGLVGGFLDKIFQWDGRNVLLRINVQG
                     EGKKELVLRDGKWLHFVADRPETPDTPSGFAVHLRKVLYNTRIMSVSQREFDRIVTIG
                     LADRDGTYQLIFELIGEGNLIMVNDGKIINALQQKRWRHRDVLIGADYAYPPSRFDPR
                     TASAEEFQTAVLTSKSDLVRTMATSVNLGGQYGEEICLRTGLDKDRKASGMTEEEIAS
                     LRSATLGLFEALREREFACLVSDGEAAIDATPYPLMVNEGYERQEMPTLSAAISAFLE
                     KKKEDEVKVDPELERLQRQLDQQLKGIEATEREAATLQSHGDMLYTSYAEVSKTLERM
                     NGLSKNTSWEKLMEQGAKVPLVISVEPQRKSFVMKLGEEKVTLDYTVAIDENANRLYS
                     QAKEMREKAAGAKGALEETRTAIAKREVKGAKAAQQAKERMLPTKRFWFETYKWFITS
                     NGRLVLGGRDAKSNDQVVKKHLGDRERYAHADLHGAPSIVLKDGADATEQELREVCQF
                     ALCHSKAWNAGAAEGTAYWVLPDQVSKTPEAGEFAPRGAFIIRGKRNYEHHLPLEMVI
                     AEVLMEGSRKISCAPRESISSEKMVVIVPGKLPRGKTASMLAKAFGVPEEEISRIIPP
                     GDLEIKETVGMNL"
     gene            22649..22723
                     /locus_tag="PKM11_02960"
     tRNA            22649..22723
                     /locus_tag="PKM11_02960"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22681..22683,aa:Thr,seq:ggt)
     gene            complement(23116..24303)
                     /locus_tag="PKM11_02965"
     CDS             complement(23116..24303)
                     /locus_tag="PKM11_02965"
                     /inference="COORDINATES: protein motif:HMM:NF018004.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HNX47502.1"
                     /translation="MVDFRPFRPYIPRLENGEGIIERVSPPYDVISADELARLKGNRY
                     NVTNVTMGGVDGNYSSAGEALRSWIEHGALAQDRRDAFYTYKQTFCEGEHCWQRTGII
                     GLLAAKGYAEGVVPHEETFPKVKEDRLNLLRGTETHCESIFGIFDELSAKLKDRIDDR
                     ETMVLEFTDPQGVRHCLFRVCDPETVESIMAELKGKTVLIADGHHRYETSSRYAQENP
                     DSPKKQFVLATLVPSNDPGLLVFPTHRLVKELPASAESFLEFVKSRFDLFDVSEPSEL
                     ASALEGRPSSDVGLVIEGKAYVASPRDLPADEMWELDSYVCQEWVLKGEAWKDEPTVF
                     YEHDTAKALAKMSEGYRLMVMLRSPSVDMIWELARLDRRMPKKSTYFWPKMWSGFVYY
                     RMA"
     gene            complement(24341..25447)
                     /locus_tag="PKM11_02970"
     CDS             complement(24341..25447)
                     /locus_tag="PKM11_02970"
                     /inference="COORDINATES: protein motif:HMM:NF015948.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HNX47503.1"
                     /translation="MASSKVYFTDMHTCQGSNLLQKMEKLLRKAGLDKMDLDGKLVAV
                     KLHMGEPGNLAYVRPNFAAVLVRMIKEKGGKPFLTDCNTLYLGKRANAVDHLNSAMEN
                     GFNRIAVGCDVIIADGLWGNEQREVVIDKELCRTAKIGSAIADADVVISLTHFKGHEL
                     TGFGGALKNLGMGSGSRCGKMEMHASSHPTVDSKKCVGCGQCVKNCPEKAITLTGKKK
                     AVIDDGLCVGCGQCIAVCRYGAPEVEWEGSSEIVNQKIAEYAFAVVNGKPSFHISLIT
                     DVSPNCDCWPFNDVPIVPDIGIAASKDPVALDMACVTLVNEASVVKGSVLDVKGRKGD
                     KFRSVHPTTDWMTGMDHAQRIGLGNKDYELVRLK"
     gene            complement(25472..27415)
                     /locus_tag="PKM11_02975"
     CDS             complement(25472..27415)
                     /locus_tag="PKM11_02975"
                     /inference="COORDINATES: protein motif:HMM:NF017215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HNX47504.1"
                     /translation="MELGLGIDTGGTYTDAAMVDLSTKRLLAWSKSPTTPQDLTVGIE
                     SSVRSLLRKERFDPTQIKLVGLSTTLATNSVLESRGGRVGLIGIGWDIEDVNSLGAEN
                     CAFIKGGHDSKGREMDSLDLKKLREIAMSMAEEVDAFVVSSMFSVYQPSHEDRARQLI
                     REVTGRPVVAAYELSGELGVVERSVTAVLNARLLPVISDFLDRIESSMKVLRIAANIV
                     VLKGDGNVMPVKLARERPVETILSGPAASLLGGSRLSGLDNCLVVDMGGTSTDIAYID
                     NGFPRIGREGAQLAGWRTRVRSIDATTVGLGGDSEIGSDMHGDLRIGPTRVLPLAFAG
                     ERTKDLPRMIMERRRTDFYVTARGPERLSGSKLQVYHRVEELGLCDEEELRSALPDLY
                     LVREMARELVHSGHLLRTGLTPTDIFNLEGLYVIGDEASSRAGVEHYLEGTRMSVEAY
                     CARVMHRMVGRLAEEIVRKVVAEEIGDLPKDATVDRLLQLMAGERSSSSFHIGIRLDR
                     PIVGIGGPSRLLMPSLRDLLGAEVVIPEGGPVGNAVGAVCSRISETLTLRIQPLSDGQ
                     FQLVTPWGDSQDFRRAEDTIRRARELAEEHVRGKADRAGAIDITVRSDVREVHFKDQK
                     GMDHLNWIEVTARATGEPRQGHH"
     gene            27515..28966
                     /locus_tag="PKM11_02980"
     CDS             27515..28966
                     /locus_tag="PKM11_02980"
                     /inference="COORDINATES: protein motif:HMM:NF040105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HNX47505.1"
                     /translation="MSGGHVQGDKGTGFPDKLSALMGELREQFVEREEEIAGALLAML
                     SGEHVLFIGPPGTAKSQMAKVMCERLRGGSFYYYLLTRFTSPEEVFGPLSLSSLQNDE
                     FRRRTEGYLPQANIAFLDEIFKANSSILNSLLTILNERKYHNGNEVVDVPILSVYGAS
                     NELPNEEEGLAALYDRFLYRFFITNVQDEGNFLKVLTSSNGKAATTTVGLEDIERIKD
                     DARSVKVDEEVLQAYLSLRKHFRSQSVYISDRRWNKTLLVLRTAAAAMGRGNVDLTFL
                     PLLQHMLWDRPEQKEGLRSLLIDLTSSGGVDLRRLQSSSEELLSLLAKAKQHSASDVQ
                     FPRPVCCYDCGSTFMSAKELCRHGESFPKHLYMDPYAREAQGVNPSYRKFELPELMHV
                     LENVRGWKVTCLRGGAEQRLYARELQDLRSVYDKVRGAHEMERGELRKRLDGNIWLSK
                     RDRHDILSRQDRRLESMAEIERSLKEVEAELKE"
     gene            28977..30404
                     /locus_tag="PKM11_02985"
     CDS             28977..30404
                     /locus_tag="PKM11_02985"
                     /inference="COORDINATES: protein motif:HMM:NF017569.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HNX47506.1"
                     /translation="MKGLIRELLERSEVQEILMAPSSIPLDHRDMAAALMASDLLGDL
                     QSLEPIDVTTMVIHSLFESKAWADARKLAKGQPDLVPELLVLALPKVIEAMANGVGGL
                     DWSELSEEERRSTEDLLEALLDAEGRGGEEVELDERQREALKLVLRMLVRSLDRSIAP
                     LIDRLQKDSEVLLRLEELLPGQGWDLHRVGLHRAKLGNLERYASMLRKHRDVDRLKEL
                     LGRMEGDKDRRASSDSCSLTETHSLIFSGDVQRMLPQEMVNLADERLKLLFYARMCER
                     RLLTYQLRGKEFRDGERKRGGPVVALLDSSGSMSGEPEMAAKALLLALARRLSEERRP
                     LRALMFSVDVEAYDLYDHSGRSQFLEFLCQTFGGGTDFDAALRQGIKSLSEPEWQGAD
                     ILFITDGLARIKDRGCLHDWNRLKERQGCRIFTVLVGGTEPGGLQRISDQVFLMTRQG
                     EWSGGSLLQEFTPQPRSIGSCWVTQ"
     gene            complement(30365..31417)
                     /locus_tag="PKM11_02990"
     CDS             complement(30365..31417)
                     /locus_tag="PKM11_02990"
                     /inference="COORDINATES: protein motif:HMM:NF016274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HNX47507.1"
                     /translation="MALQKGTPLSKGYRMPAEWAKHDATWLSWPKNPLTFPEEVIDEV
                     EGVFAQMTAALSSGELVKILVDDDALEERAYAKVSKAGADMSRVRFERIKSADVWIRD
                     YGPSFLLHKDTGKKAAVKWDFNAWGAKYDDLLYDDIAGQHVVESSGVPYFKPGIVMEG
                     GSIDVNGKGLVLTTEQCLLNKNRNPNLDRLRIEDYLKQYIATPDVIWLASGIEGDDTD
                     GHIDDFARFSSTTSVLCAFSDRGENAPVLERNWSLLEKAQDRFGLELQRLPMPEPLYL
                     EEEDRNLPASYANFYIGNKVVLLPVFEDPMDKVAVEIMSSHFPGREIVPIVARELVYG
                     YGGIHCVTQQEPIERG"
     gene            complement(31420..32298)
                     /locus_tag="PKM11_02995"
     CDS             complement(31420..32298)
                     /locus_tag="PKM11_02995"
                     /inference="COORDINATES: protein motif:HMM:NF012993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HNX47508.1"
                     /translation="MPGERMLKVGLVQMAMSSDVTDNLEKAVRMSEEAASRGANIICL
                     PELFTTPYFPREEDPEGKRERGGFLSTIPGLVTETLSDLAKRTATVVIGGSIYEAAED
                     GLFNTATLFEKDGKMLGGYRKTHIPHDECFYEQDYFKPGDTGFQAFPTSCGKVSALIC
                     YDQWFPEAARCCALLGAEIIFYPTAIGTVRGIGEAEGDWQEAWENVMRGHAIANAVPV
                     CAVNRVGTEGDSEFYGGSFVCDAFGKTLARAGKGEEVLVAEVDMDHGKRVREGWRFFH
                     NRRPECYGALVEKREE"
     gene            complement(32338..32886)
                     /locus_tag="PKM11_03000"
     CDS             complement(32338..32886)
                     /locus_tag="PKM11_03000"
                     /inference="COORDINATES: protein motif:HMM:NF025030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HNX47509.1"
                     /translation="MVDIELDGILRGLRSLNVEECRAALEDSRELLMAGWADRRLLQA
                     LIPLTEVENDQVRKDSSWCIGKLAQMKIGDPRSVPSLILLTTDRDEEVRSNAAWALGE
                     LAGQSIGDTISIEALNILLTDPDREVKGMAAWALGRMADKMRVTSPSSVPLLEAMLLE
                     NSEFLRKGAEWSLERIRRLHPL"
     gene            complement(32911..33096)
                     /locus_tag="PKM11_03005"
     CDS             complement(32911..33096)
                     /locus_tag="PKM11_03005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47510.1"
                     /translation="MAEETEKGPCLWHAPDNRCANCKARRYRLDALGMKDIYGECRGQ
                     EDYRTCEFYKLKPVPKC"
     gene            complement(33247..33319)
                     /locus_tag="PKM11_03010"
     tRNA            complement(33247..33319)
                     /locus_tag="PKM11_03010"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(33284..33286),aa:Val,seq:tac)
     gene            33458..34051
                     /locus_tag="PKM11_03015"
     CDS             33458..34051
                     /locus_tag="PKM11_03015"
                     /inference="COORDINATES: protein motif:HMM:NF014090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005384 - manganese ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030026 - cellular manganese ion
                     homeostasis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VIT1/CCC1 transporter family protein"
                     /protein_id="HNX47511.1"
                     /translation="MAKNDGKGSWFKEAMSLPETGPALRRYFVNTMFDSTFAVLGIII
                     GSALTADADSGLVIATIITSCVALAISTGSSVYEGETLEQSRRMDEIGRAMLRPVEET
                     NLGKASKASAAIIALSNSLAPLMSGAIIVSPFVLLGDETILVAAEVAIVLAIILLFIT
                     GFIMGKISERNPWWKGMRMALVGVAAFFVCYMIGGAV"
     gene            complement(34053..34706)
                     /locus_tag="PKM11_03020"
     CDS             complement(34053..34706)
                     /locus_tag="PKM11_03020"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HNX47512.1"
                     /translation="MSEGEQRKQWNSTYSSKPNFFGAEPSDLAVRAVDIFRKNGCRKV
                     LELGCGQGRDTCLFAKEGFQVIALDYSDSGICQMRERTKEMCLDGNMECMCQDLRAGI
                     PLPDGSVDAVYSHMLLTMELWEKDIQFILDECRRVLRPGGLNLYSVRNDHDPHFGKGP
                     HKGEDMWQNPIGFVVHYFSEDKIKRLSRGYDIVHVREFDDPSPPFTKKLYEVLLRKP"
     gene            complement(34716..35408)
                     /locus_tag="PKM11_03025"
     CDS             complement(34716..35408)
                     /locus_tag="PKM11_03025"
                     /inference="COORDINATES: protein motif:HMM:NF014635.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HNX47513.1"
                     /translation="MARDLKETLGLKHEPVAITLIKKGHALPSDYPVTETPVRHCGTI
                     MRARKGEKLLVTPEKEACPVGASALGMVPVPEKVASGEFHANMGMFKDPAAAKQTLEM
                     RTSFHLGDVIGVAAAPLDKATLVPDVIVLTALPEQVFWLIPAAQTYEEGGRVSVEMAA
                     VQASCVDATVIPIVKGKTNISLGCFGCRKTTDIMAEEMLIGIPFKNFEKIVATVKTMG
                     AGAIPKSRAKSL"
     gene            complement(35539..36585)
                     /gene="hypE"
                     /locus_tag="PKM11_03030"
     CDS             complement(35539..36585)
                     /gene="hypE"
                     /locus_tag="PKM11_03030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="HNX47514.1"
                     /translation="MKRVTMGHGAGGEMMQELISKSIAPFFPKIKIEVPLDSMDDAAI
                     VDDIIFTTDGHTVKPIFFPGGDIGSLAVSGTVNDIAVMGGRPLALSMSMILEEGLEIE
                     VLERVTKSIGRYSEMAGVPVVTGDTKVMEKGAIERMVISAAAVGKRHPAMDHNLKIAS
                     SYRKVDSRWLTDDNVRDGDVILVSGTLGDHGIALLSFREGYGFESQVQSDCAPLNHMI
                     GKLLEVGGITAMKDATRGGFANAINEWSSKSKVGMELVEKDIPVADAVRNASEMLGLD
                     PLTIGNEGKVVIACVPEMAEEVLKALRSDEHGRNAAIVGHASKAVKHVMMRTEVGGRR
                     ILEPPVGDPVPRIC"
     gene            36687..36764
                     /locus_tag="PKM11_03035"
     tRNA            36687..36764
                     /locus_tag="PKM11_03035"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36723..36725,aa:Arg,seq:tcg)
     gene            complement(37012..37719)
                     /locus_tag="PKM11_03040"
     CDS             complement(37012..37719)
                     /locus_tag="PKM11_03040"
                     /inference="COORDINATES: protein motif:HMM:NF024098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HNX47515.1"
                     /translation="MTRVLVYIDESGMTDASESVFTVSSVWCCPSTTRGAQNALRYTI
                     DAMKPVANSFLKSQKKEIHHSDGLGQISATLLETALHASHSDNSILRGDGIILKEPLC
                     WRTVDFSPEFEHQIANGNEPCGNWIRARSIVSNLRPLLTFQKNGKFEVGVVLDSEVWG
                     KALELCKYMILDNLKDKGITISFDFERSNRIPGLQIADMVSGVARQYYRNQKEQDAFD
                     LVRKHSFEHLKPIQRPK"
     gene            complement(37971..38546)
                     /locus_tag="PKM11_03045"
     CDS             complement(37971..38546)
                     /locus_tag="PKM11_03045"
                     /inference="COORDINATES: protein motif:HMM:NF025432.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4256 domain-containing protein"
                     /protein_id="HNX47516.1"
                     /translation="MAKEMVKELTSEQREALLAVLQARFEENQSRHKDLDWSKVQARL
                     NADPDRLWSLQEMERTGGEPDVVGCDRSSGAFIFFDCSKESPKDRRSVCYDQEGLEER
                     ERKGVHPAGSALGMAAAMGIELLTEEQYRDLQRLESFDTKTSSWIRTPTNIRALGGAL
                     FADRRYGHVFVYHNSAPSFYSSRGFRGSLRM"
     gene            38659..38808
                     /locus_tag="PKM11_03050"
     CDS             38659..38808
                     /locus_tag="PKM11_03050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47517.1"
                     /translation="MTKSNISLGGGIIDGMILIIAPFLPTIVLLALVYMTLNKRKKKE
                     LAAKK"
     gene            38948..39889
                     /locus_tag="PKM11_03055"
     CDS             38948..39889
                     /locus_tag="PKM11_03055"
                     /inference="COORDINATES: protein motif:HMM:NF004846.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HNX47518.1"
                     /translation="MADNWNWRDDRIPRIDGKRVIVTGAASGLGAYIAEALSAKGAFV
                     VLADKDIIGARSVADRIRSSVPGAEPTVHELDLADLDSIERFASWYQAEHNTLDILIN
                     NAGIMTPPYGRTAQGFESQIGVNHLGHFALTYHLFPLLSATTGSRLVTQTSIVHRGGK
                     INFQDINSERSYSPWNAYKQSKLATLLFSRELDRRLSYIGVDAPMSIACHPGLVNTQL
                     YRNRERMRSWLRPFMHDLEAGAMPALRAALDPAAKGGQIYGAGGWMEFKGPAVLVPPH
                     RRGKDMELASRVWDLSEKMTGLDLSARIKERRPSASR"
     gene            39925..40218
                     /locus_tag="PKM11_03060"
     CDS             39925..40218
                     /locus_tag="PKM11_03060"
                     /inference="COORDINATES: protein motif:HMM:NF037968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET transporter"
                     /protein_id="HNX47519.1"
                     /translation="MDQLTVVGLLAGLITTLGFVPQVVKGYRSGRMEDVSLIMPAVLM
                     VGMGLWLVYGIFLNDLPIILWNAVSIALNAVMIFLKLRSDRGKKKGADPQFTR"
     gene            complement(40208..40924)
                     /locus_tag="PKM11_03065"
     CDS             complement(40208..40924)
                     /locus_tag="PKM11_03065"
                     /inference="COORDINATES: protein motif:HMM:NF024247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HNX47520.1"
                     /translation="MTSDHSDTIYQKIEAAARESGSGLVGFADLSPLKGMLAGDATTF
                     EFPYAVTFAVEIPKEAALASLKKPSEEMRSAYKMCNKKLKEAGEKIVQILAAEGYQAR
                     FVDPALRVDKEKLLGPISQKAIASLSGMGWIGKNGLLITEEYGARQRMGAVLTNMPVT
                     RQAKLIDNQCGDCTACVDRCAMKVLKGPNFKHHPESRDLVIDWAKCGVYEAKLIGDGS
                     KPEMACGRCISVCPFSRVSE"
     gene            complement(40980..41357)
                     /locus_tag="PKM11_03070"
     CDS             complement(40980..41357)
                     /locus_tag="PKM11_03070"
                     /inference="COORDINATES: protein motif:HMM:NF033788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HNX47521.1"
                     /translation="MANEGVGGSGEGNCSLPKEVADGLRDAGGREGLLSKVPDKDSIK
                     DQADRHQALSDPVRLQIVHLLGVSELCPCVLKELTGLTDSKLSYHLSILEKAKLTVWR
                     QNKNWRVYSLTEQGRSYLDGRSI"
     gene            complement(41437..41700)
                     /locus_tag="PKM11_03075"
     CDS             complement(41437..41700)
                     /locus_tag="PKM11_03075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47522.1"
                     /translation="MDIDLLTLANLLLCLTIVGLGLLGYRRSKHTLPLMLAGVFALFA
                     VSHLMILVGLFDGLELVVFGIRVAGYALVIYLLYRYVQVLDIF"
     gene            complement(41744..42532)
                     /locus_tag="PKM11_03080"
     CDS             complement(41744..42532)
                     /locus_tag="PKM11_03080"
                     /inference="COORDINATES: protein motif:HMM:NF013328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase family
                     protein"
                     /protein_id="HNX47523.1"
                     /translation="MPELPEVEMARMLVQDRLNGKRVASLQVKDHKMLTNGSERTMRE
                     AFIGRSVGDAHRHGKNLLVRIGDDHLFIHLGMSGSLHLVDDRETTPHERLRLGLDEGA
                     LVLDDPRRFGRFGLYHRLEDLLTERDLGPDALTMSDKVFVSQMAGRRGSIKPLLLDQS
                     LIAGVGNLYADETLFQEHLHPATKADTIPEANMARLGKRVRKVLEASISVRTEFSRLP
                     EGFLLRDRREGAACPRCSTELAAIRIGGRTTILCPECQSLRTKP"
     gene            42650..43084
                     /locus_tag="PKM11_03085"
     CDS             42650..43084
                     /locus_tag="PKM11_03085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47524.1"
                     /translation="MSDNEWACGDRRDWRSVKGMSWRVTVSAVSALGWFGFVIAWLFF
                     LADGYSILQNLAVLMLSVVALAIINVTAWMTFAQSMGELKDISCEGEKHGMAKGALAL
                     IWLVAIGVWLFWYAGDYSLYQNLAVLLLSIVPVAGIGMLLGK"
     gene            complement(43086..43427)
                     /locus_tag="PKM11_03090"
     CDS             complement(43086..43427)
                     /locus_tag="PKM11_03090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HNX47525.1"
                     /translation="MGNRLKLTVFSVSCCHPQTAVHDKRYLELIRQVLEETGVEADLD
                     LVTATEARMSLTYFFVGAIQPLYGKYGPAVAPALFVNEKLTLFGGVPSKEKLKEVLEK
                     AASEPPSLLMW"
     gene            complement(43417..44337)
                     /locus_tag="PKM11_03095"
     CDS             complement(43417..44337)
                     /locus_tag="PKM11_03095"
                     /inference="COORDINATES: protein motif:HMM:TIGR00345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015446 - ATPase-coupled arsenite
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0071722 - detoxification of
                     arsenic-containing substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRC40/GET3/ArsA family transport-energizing
                     ATPase"
                     /protein_id="HNX47526.1"
                     /translation="MTQESMREIIEKRKFLFFGGKGGVGKTTMAATTATWLSDHGYKT
                     LIVATDPTVSLSAIYGQEISATDITKIGTERNLCGLNINPKKAMGVFQTRLEGMMEGF
                     SSMFGSELLSTPCTEEIAAFDQFVSYFEDTEHDKVVFDTAPTGHTLRELSMPFDWSGY
                     ISNQIKNRRELSEVLGFVYDENMVADLEAEKARYDKSVRGLSDETVSAFNLVLLPEKL
                     PIEETARAIEDLGGFGIKVKSLIINEVIPREVLQGNWFLERRRATQDKYLKEIAQRFS
                     AIPSIEVPLFDTDVYGMEMLRKVGRELYGK"
BASE COUNT         9239 a        13112 c        12746 g         9505 t
ORIGIN      
        1 cgttcctaag ggcgacatat ccctatacgc caccgccacc gtgaacggcc aggaggtagt
       61 gttcctggag aaggtcatcg ccaccgacag cgccgtgatc gacctggtcc tgacaggcgg
      121 gatggtactc tccggaacgg tacagtattc cagcgccgcg gtgtccgggg ccgatgtcgt
      181 gctgcaggac cgcagcggag gggccacgct caccgccgtt accaactcgc aaggcaagtt
      241 cagggccgta ctgccctcgg gcctatactt cacgtacata aacgacggca ccagggccta
      301 ttggggcgac gtgaacgtcg tctcctccat gtccatgacc ttccagctcc tgacctcggt
      361 caaggtcagc ggaaaggcct ggtatgacgc tgacggtaac gacgcggcct ccgccgcgga
      421 gggactgaac ggcgccgtga tcaccgtcac cgaccaggat ggtcgctcgg tgaacatggg
      481 cacgagcccc accggtcaat actccttcgt gctggtctcc ggaagaacgt acgccctgac
      541 cgcggtcaag gatggcttcc agaccctggc gcggaactat ccgtccatat ccctgagcgt
      601 cacggacgac ctggagatgg tcgccctgca gaggacggtc accggaagcg tttccatgga
      661 cttccctggg gacaagggta acctgaccgt gaagttcgtc gcggtcagcg gcccggccat
      721 ggacaatcaa acggtcacca acgccgacgg cacgttcagc gccatgctct atcctggtaa
      781 gtacatcgtc ctggttaacc agaacgtcac cgccggggac ccctcggtgc gctaccaatc
      841 cctgagcgac caggacctgg aggtcctggt cggcagcgac ccctcgtccc tgcagatcga
      901 gctggtgaag agatcattgg tcagcggggc ggtcagtccg agcggtacgg ccaaactggt
      961 cttcgatggg ccggacaagg tgagcgtcac cgccggccag acctattcat tgtatctgca
     1021 ggacggttcc tacaacctgt acgcgaccgt gtccaacggc tcccgtaact acgctgcgct
     1081 cagccgggtg aacgtcaccg gcgccacgcc gctaaacatc accaccagcg acgccgcccc
     1141 ggccatcata caggcgacca tgagcggggc gagggcccag agcatcgtca tatccatcga
     1201 gctcgcgggg gcctattaca acgtcaccac tcccgacaat ggacaggcca gcgtctatct
     1261 gcccgtcggt tcctatgtcg cgtccgtgga gcattccacc atcttgacca ccgcatcgca
     1321 gtcgaggttc gtgaagtacg tcggagagca ggacttcacc atgtccggtt cccgccgtaa
     1381 cgtggccata agcaccgtca tgtcctacga gaacgccacc gtgagcggca tcgttaccgc
     1441 agacggttcg gcggccaccg cccagatcga gttccaggct atgtcggcca ccgcccagga
     1501 cctcaccgtg agcgccgttg gaagttacgc tgtaggtctg tccccgggca attatacggt
     1561 ttatgcgatc aaccaggaca gctcccgggc ctatctaggc aagctctcga tcaccgacct
     1621 tgatgatgtc acctacgaca tagtattggt cgaggccttc cggctttccg gggttacgtt
     1681 cgcccagaac gacggcgtaa gctccgaggt cagcgtgaac gggatgatca gcatgaccag
     1741 ttccagcgat ggagcttatg agatctatct gcccggcggt tcctatacgc tgtacgcaga
     1801 gacggctcta ctggagaacg ggctgctcgt cgattaccag ggttccgcgt ccgtctcgct
     1861 aagcgacgtc accagcaagg gcatctacat gcagcgggtg gccaagcaga aggtatcgct
     1921 cacctgggat ccggctcaga aggtcacgtt gaacgctggc gagaccgcca cctacaccat
     1981 ccggatcgtg aacgacggta acctgcagga caccttccgg ttgacatcca cagccaccgg
     2041 ttggacggtt gtgctctccc agaccgaggt cacccttggt tacggggctt ccaacagcca
     2101 gacggtgacc gtgcagctga ccccctccgc tagcgtacta gtgaagcaca ccgccgtaat
     2161 agtccgggcg gtctcgatca ccaactcctc ggcggccgcc tcggtcagcc tggacgcagt
     2221 catcgccccg gctcgcgcgg taagcatggc ctaccagggc ggagattcca cgaaaggtga
     2281 tgaatacgtt cacaccgtgg cggtcaccaa cgccggcaat gtcgacgata cgtacgccat
     2341 atccataggc aaccagcagg cgttgcggga cctgggctgg gaggtcaggc tggtcaacaa
     2401 gaccgccctg gccgattccc tgtccgtgac cgtcgccgcc agcaagagct cggagataga
     2461 ggtgtccatg gtgcccctgc gctccaaccc cagccccacg gtcaccgtgc agctggtaac
     2521 gacgtcctcc gccgatcagg cggtccgcag ctctttggac gttgaaccgc agttcgtggg
     2581 actggacggt aacggtctca cggtcaccgg cgtgaacgtc gaggacagca cgcccaccct
     2641 gggtcagggt tcgatcgtcc ttctaggtct ggcgttggcg ctgatggcgg tgcttatcgt
     2701 cctcagcatg cagaaggggg tgttctcacg aagaaagcgc tgatgctgat aatggcggcg
     2761 ttgctgctgc tgaccgtgat gcccatcgcc caggcggata cctacgatcc gctgtacgcg
     2821 cagatcgacg gtccgagggt agtggccacc aactcggtga ccatgtacac cctggtgatg
     2881 ttcggcggtc cggccgaggt cggtgttggc aattacacgt acaaggccac catgaccggc
     2941 tccgggaaca cctacggcgc gtccttcata ccgggaacgg tacaaccgtc accggacggc
     3001 acgttctaca tcaatctgac cgcgccggcg ggtccgcaga cgctgagcat tcacatagag
     3061 tgcatgtcca taggtctcag tcagacggtg aagaccacca tcgacctcca ggtcaaggtg
     3121 gtcgagccta tatctctgcg gtccaccatc aagaacaccg gtgaggtggc cgccgtaggc
     3181 gtgccgatca gcctgcagct ctaccaggac ggtcagtggg tggagttcca tcggaccacc
     3241 gtggacctgg ccgcagggca atcgtaccag ttcaagtaca actggaccgc cacggacctg
     3301 gcctccggcg agcacaaggt acgtatggtc ctcgacccca acaatgatat tgtcaccttc
     3361 gagggcggtt cgtccgtcta cgagacgaca atatactaca agatgcccgg ctacgattgg
     3421 gtcaacacct tgctgtgggt actggtggtg gcgctaggcg tgaccatctt cttcgtctgg
     3481 agacgaccgg ccaagggcaa gaagaagcgc taaacccctt ccctacaacc ttttctccag
     3541 gtcgcccatg cggccgtgca gcctctcgct catcacagcc agggacacgt ctcccctagt
     3601 tttttccaat actgagcggg cgatgtcctg cttgcgcctt atcgaaacga tggcgtccgg
     3661 ataatcgaag ctcatgatga ccaggaacag ctcctccatg aggtccaggt accgctcggc
     3721 ctcggagatg ctgccccgcc gcagcgattc caacgagaaa cgtctcagct caccgatggt
     3781 gtcggccatt cccagaagat aggaggtgcc cggcattccc aggtgctccg ggtccggcag
     3841 ttcctgcccc ttgaccaagg cgttcaggat cgccgcctcg gccacctcga ccagggcgtc
     3901 ctgcacgatt ccggagtacc agatctccac gtgctcggaa agaacgctct tcagcttatg
     3961 cgcctcgtca atcgcctcgg ccagggcggc ctcgccgtcg acgcccttgt gcataccgtg
     4021 gaccactccg ctcgacattc tgatgatcgc gcgggaggac ttgatggcga tctcccttac
     4081 cgtatccttc tcttccaggg agtcctgtat cctctgggcg atgtgctcca ggttctgcat
     4141 gaagggagat tgtctgggta tatgataagt ttgctcagtt tcggacctgc tgcatgtgct
     4201 ccacccttcg gcgcaccagc tccctcttgc cgatgtcgtg acggacgaat atctcgccct
     4261 gcacgtgctt caggccgtcc tcgcagatgg cctccgcctc ctcgatggaa tcggccattc
     4321 ccaccacgcc caaggtgcgc gaggatgtcg tcaggaccat gccgtccttc tcgtccaccg
     4381 ccgcatagta caggcgggcg ccggtatctg ccagcttcct ctcgttcacc atgaccggtc
     4441 gcccagcctt tgactccgtg ccgtaaccgg cgggaaccac gtacttgcac acggtggcct
     4501 ttttgaggaa cggaacttgc ttggagagct ttccatcagc gacaccctgg cagacgtcca
     4561 ggaagccgtt ctgcagaagc gtcagaacgt tcatcgcctc cgggtccccg aagcgggcgt
     4621 tgaactcgat gaccttcggg ccatccttgg tgagcatgaa ctgcccgtat agtacgccac
     4681 ggtacggaga accgtcctcg cgcatggcgt ctatcgttcg ctgcatgatc tccaatgcct
     4741 tctggcgttc cgcgtcggtg acgaacggca atagatggtc ggcgtcggtg tacgagccca
     4801 ttccaccggt gttcggtccc acgtccccgt cgtaggcgcg cttgtggtcc tgaacaagcg
     4861 gcataccccg aacgtttcgt ccgtcacaga aggcctgcag ggtgaactcc tccccgacca
     4921 ggcgctcctc gagcaccacc ccggcgccgc cgatcttgtg ttccagcacc tctttgacgt
     4981 aagcgaggac tcctgacttt ccctcaagat gctccccttc caccttgacg cccttgccgc
     5041 cggtgaggcc ttccggcttg acgaccagtt cgccagggaa atcatccacg aacagcttcg
     5101 ccgaatcata atcttggaag gtgccgaagg ctacgttccc ggggatgttg tgcttcttga
     5161 gcaggcgacg tgagaatcgc ttggacgtct ccagccgagc cgcggcttgc gaaggtccga
     5221 cgcatccgat gcccctcttc aacagctcgt ccgccagccc cacttccagc ggggcctctg
     5281 ggccgatgac cgcgatctcg gcgccgcaag atgaggcgaa ctcagctacc tttgcgacgt
     5341 ccgtctcctt gagcagcttg aactcctggg ccgagcgggc gatcccgggg ttgtggttct
     5401 tcattgccac gtaaacggtc gcgccatccc tgatcagagc ttcgacgatg gcgtgctccc
     5461 gccctcctcc gccgacaacc agcaccttcg cggtcatgcg tttcggggat ggcgctgagc
     5521 attattaaat gaattgattc tcagaccagc agcgcttcca ccagggcttc caagccctcg
     5581 ccggtgcgct cgctcaccgt taaaagttcg cgcccgccgg acagcttgcg atagtccgct
     5641 ttcaccctag cgatgtcaat gcccatgtac tccgcgaggt ccatcttgtt gatgacgcca
     5701 acgtccgccc cctgaaagat catggggtgc ttgcgcacca tgtcatcgcc ttccgtcacg
     5761 gagatcacga ccatgcgctt gtccgtgccc agcgggaagt ccgccggaca tacgagattc
     5821 ccgacgttct cgatgaacag gaatccgacg ccttcaaggt ccatgtggtc cagggccttg
     5881 tcgaccatca gggaatccaa atggcattcc tttccagtgt tgatgttgaa cgccttgatt
     5941 ccagcttctt ggaatcgatt gaaatcatcc tgaccggtaa catcaccggc gatcacggcc
     6001 acatttatgc ctttcttctt catctccttt gcgagtctga tgatcaaggc ggtcttgccc
     6061 gaacctatcg agcccatgat gtctagggac ctaatgccct tggaacggag gttctcatga
     6121 ttgtgatctg ccagatgctt gttctcggca agaacatctg tctccatgga aatattggtg
     6181 atcttatgca ccttttcaac aacggtgatt attcacttaa ttatttccaa agatcgcatc
     6241 gaaggtgtga cgggaactat ttaaatattg atatctcctg gatttagggg caagaaaaaa
     6301 cgaatccaca gaaatatttt ggttaatatg atcaaattga agtgggagat tctgacgaat
     6361 cctacaatac atttatattt ccccaataaa ttcaagacct aatcaatttt cgcaaggggg
     6421 atgaacaatt gtcaaacgag gggattaatc aaaataggtc aattgctcaa acattgacga
     6481 gtaaaaaata tttgtttttg tttggggcat tgctcttagt ttgcgctgct tttttaatta
     6541 ttggcgctcc gaacgccagc gcggcagggc cgacctatga atatggtgat attactacga
     6601 acacggcttg gaccgaggca ggttcgccgt atattgtgaa cgacactata accgtcaatg
     6661 tcggtgcgac attgacgatc ggtcccaatg tgaccgtcat ggtgcagcct ggaaatatga
     6721 tcattgtcaa gggaacgatc gtagcggacg ggacggccgc tctgccgatc acattcacta
     6781 cgaacgatac cgtaacattc gttagatgga acggcatcga aattcagtat acctcaaccg
     6841 gttccttgtt cgacaacgta ttcatcgaca aggcgggagg aaatgcaggt atcactgtcc
     6901 tgaatgccac cgtgggaatg acatatgtga cagtcaacaa ttcatactcc ggtgtcgatt
     6961 atcagtttga gaacaaggca gtatccatat cggtggacaa ctgcaatttc acgcacatgg
     7021 attatttcgg tgttaggatc aacggatatg catgggccgt tgacagcaac gtgaccgata
     7081 taacggtacc aatatccata accaacagca tcttcgatgg caacgggtat ggcgttgata
     7141 tctggtggct cgaggcaaat gcgcaagaca acgccactgc taagatgacc tgcgacatct
     7201 ctattctgaa caacaccttt gaaggttcca attcggcagc gatttactac gacctgaatg
     7261 ttgatatctc tgagaatggg acggtagtca tcgccggcga cattctgatc aagggcaaca
     7321 cgatcaagac ctctaactat ggctttgaga aggagaatga taatgacatc cgagccgaag
     7381 acacaagcga tgtcatgatc tctggcgaca tctcgatcgt caacaacacg ttcgaggacc
     7441 tcgttgatga tgcgatatat cttaacactc aagttgagta tgtctatgac gaagcgacag
     7501 tgagcattct cggagacatc tcgataagcg gcaacacttt cgaggatatt ggcgggtctg
     7561 ctatttactg cgagaagtac atcggctgga actcatatgt gtatgatgac gctgaggcca
     7621 cgatctctgg cggcatctct gtcgtcgaca acacaatcaa gaacgtcgat tatggacttt
     7681 actatcaact gtacatagat acggatgata acggaacagg atcgataagt ggggacgtca
     7741 ccgtaactgg caactatttt gaatcatgcg gggacgatgg catctatgtt gagaaagagg
     7801 gaggctcacg cgatgagaac tcgaccacca acatggacgt cagctcatat gtgaacaaca
     7861 accagttctg gaactgcagc agtgatgcat tctatgaata cacttatttc gaatcggacg
     7921 gatacggtgc catcagcatc tctggcgaga cgatcttctc agagaacgta ataaggaaca
     7981 ttgaccgcta tgtcatggag gtcgaacgcg aactttattc atacgatctc agcgagcttt
     8041 caagcgattg tccgtattct atgatcaaca acgacgtggt gatcgctgac gaactcatcg
     8101 acatatatcc gtattactat gcgtacgatg agtccgtgat gaacatcacg aacgaaaacg
     8161 ttgttatcac tggcaacact gcccgccagc tctatgatta tagcctatat gcatacctat
     8221 attatgagag ctatgatgat gcgagcctga acgtatctgg caagatcgac ttcatcgata
     8281 acgatgtgaa ttgcctttat gatgagagcg cgtacatcga gaggtatatg gacgtcaggg
     8341 atgacgcgat attcaacgtt ctgtatccga tcacgataca ggacaatgtc ataagcgtcg
     8401 atgatgggga tgattattat gcgatctacg tttatgatgt gctggatgcg tattcgtcct
     8461 tcaacaacac cgcgacaata tccggtgatg tgacgatcga gaacaaccag atatccatca
     8521 tatctggcga cggcatctat ctctatgttg atatcgatgt cgagaccgat gatgattaca
     8581 cctcggccat cgccaattac gatgtgaact atgtcatcca ggataacgaa ataaccgtct
     8641 tcaatgacaa cgcatgggat tacacatacg gtatctacgc atacctcggt tgttatctgg
     8701 aatcggatgg agacatgggc gcggcatccc tcacggtcgg tgatgtcctg atcgagggca
     8761 acacggtcag catgagcgga gagtcgtatc tctatggcat ctatctctac atctacgccg
     8821 agtcttattc gtatggtggg gatgcaacat tggtgctaag tgagttcagc gtaactgaga
     8881 acaccataag cctggatacc tatgacggat atgggatcta tctctattat ccgtacttct
     8941 acgtatatgc ggataatggt aatgcaacgt tgaccttgga ttcgatcaat gttgtaggta
     9001 acagcataga caccttaggt gactccattt atggcatcta tgtctatgag ccggatttcg
     9061 aatgctacgt gtatggtgga gattggtggt atctgaacac ggccactctc gaggcgacca
     9121 acggtttcaa catcgatgac aacacaatat caatggtcgg cgattacacc tatgcgctct
     9181 atttggaata tgtgtatcgc tatgtgtatt ccgatgatta ttggtcccaa gcaactgtga
     9241 acgtaccaat atcgatctcg ggcaacagca tagtccagac gggattggcc tcctatggca
     9301 tatacctcta ttatgtggac tacgacgttt attacgacta ttcgtatgcg acgttgatcg
     9361 ccccgatgga gatatctgac aacaccgtcg agtacatcga gaatgacgac tacgcgtacg
     9421 gtctggacgt cgagtctatc tatcttgatc tcgccgatcc aacctatatt ggcgaatatg
     9481 tactggatat accgatcgtg atctccaata acgttgttgt cgctggatac gatggtattt
     9541 atatctacga tagcaccgat ggtgtacagg tattcgtaac cggaaacacc gtttctgaga
     9601 cgaccgacta tggcttgtac gtcgatgatg tcgagtactt gtatgtcgag gacaacgtgt
     9661 tctccaacaa catgggcgat ggtgcgtatg ttgagtatct agtgaactcg gtgatcggaa
     9721 acaacacgtt ctctgagaat ggggaatatg gactttatgt cgactatggt tgcgagtatc
     9781 tgaccatcta taacggcgtg tatgacgaca actcctacat gggcatctac atctatggtg
     9841 gaaagggtgt atactgggta gtcgacgctg cgtctgagat cgtcaacaac gacgccgaga
     9901 tctacgccca cgtcgaggtt agagccggcg gggttctgac catagacagc gttcaatcct
     9961 tcctgcttgg agatggttat gacggggtca cccttctcaa ggtgctcgag ggaggaaagc
    10021 tgatagtcgg gaactcatgg ctcgagtcag atgacgggga tggacggttc cttatccacg
    10081 gtgatctgga tatgtccaac acctggttaa cacaatggtc tgagctatat ctcggtccta
    10141 ctgcaactgg ctcgatcagt gcatcctaca taagcgacaa cgacaagaac ggtatccaca
    10201 tcgatggctg ctcaccccgg atatccctga acacgatctc agggaattat atggatggca
    10261 tattcatcga gggagcatct gcttcgccga ggatcaccaa caacctcata actgaaaaca
    10321 gccgtggcat cagtgcccgc ggatgtgatc tgaaccaggt cattggtaac atcttcgtgg
    10381 gcaacgatgt tgcaggattg tacgcccaaa acgtaactgg tgcgatccat ggtaacacgt
    10441 tcctgatgaa caggatcgag atatacgtaa aggacagcga cgtatcgatc caaagcaatg
    10501 agatcggata tgctaggatg ataggtgctc tggccaagtt tgggccggtc tctcagttgc
    10561 tcaacaacat gtccgggaac atcgtctctg gattgatgtc aacctacctt gaggtttcat
    10621 ccgaatcgat gttcaaccac atgggtatct ttgcggagag ctcgacagtt aaggcgtccg
    10681 gcaacaccta tgggatgctg tactacgcct tctatgccga ggattcgaca gtgacgttca
    10741 gtgatgacct gacatcaaac aagatcgtgc tctcactgtt gaacgccaac ctcgagcagg
    10801 tgaacatatc ggtgccgacc tatctgttca acggcatcta cgcttcgaac tctgcggtcg
    10861 agatcaagga ctccaggata gaatgcatgg agaccgcggt cttcctggac acctgcaccg
    10921 gttcgatcac gaactgtgaa ctggtggccg agagattcga tgtgtacttg accggtgact
    10981 gcgacgtgtc gctatccggc acgaccctgg acggagagct gaaggtcgag ggttcctcaa
    11041 ccttgatggt atacaactgg ctggacgtca tcaccaagaa tgatgacaac gaaaccatgt
    11101 ccggcgttac cgtcgagatc aaggactctg caggcacgct catctccaag ggcaagagcg
    11161 atgacaacgg tgtctacagg gcgagcgtcc ttgcgtatac cgttaccagc gagggtaaga
    11221 actataccga cgcgtacaag gtaaccgcgg acttcgataa cggcaaggtc agcaagaagg
    11281 tcaccctagg tgacagctcg gtcactgagc tcaccataga agccaacaag gacaacaccg
    11341 tcttgtatgt gagcatagtc ttcatcatcg tggtcatcct actgatcgta gtggtcatgg
    11401 tgatgcgccg caagaagaag gcctaaacct tttccaactt tcttcctttt ttttcctttt
    11461 tttattttat ttctcaaaaa agagttaagt tgtaaatgcc atcaccgctc ggtgccttga
    11521 attgagctat tccgagttcg taatgacatc cctcgagacc gctggtgcgg aggaagggga
    11581 cacgctcgag atcgtatcgg ggaaacgctc gtacaaaggg gtgctcatgc ctcatcacga
    11641 gttcagccat cccgatgtca ttgtgatcaa aatgaagagc ggttacaaca tcggggttaa
    11701 gttatctgca gggtccaagg tctcggtcat cgagaagagg gaggccaaga tgaagccagc
    11761 aaggcctcaa agatctgatg ataacttaaa gaccatcgca gtgataggaa cgggcgggac
    11821 gatagcttcc tacgtggatt acaggacagg cgcggtgcat ccagcactgt ccgcggacga
    11881 catggtcggc gcggttcctg agatatcgtc aatttgcaac gtcaaggccc gcgtgctatt
    11941 ctccattttc agcgagaaca tggaccccga gtgttgggtc gccatagcca aggcagtgaa
    12001 ggaagagctg tccaacggtg cggacgcagt tatcataccg cacgggacgg acacgatggg
    12061 atacacttcg gccgcgcttt ccttcatgct agatggattg gacaagccag tcgttctcgt
    12121 aggcgcccag aggtcctcgg atcgtccctc ttccgattcg tataccaacc tcatcgccgc
    12181 cgcaaggttc tgtatagaga catccatgcc aggcgtcttc gttctgatgc acgagacgct
    12241 atcggacacg accgcggtcg tgcacaaagg aaccagggtc agaaagatgc acacaagtcg
    12301 cagggacgcc ttcaagagca tcaacagctc gcccgtggct aggatcaatt tcgaaggtaa
    12361 gatcgagatg ctgtgcgacg agacgccgaa acccgcggca tccctggtgg taaaggatgt
    12421 tctcgagagg aaggtcgctc tccttcagtt ccaccctagc atggacgtcg agctcttcaa
    12481 agagctcatg ctcaagcaca ggggcatagt catcgccgga tccggcctcg gtcatgtctc
    12541 cacgccgatg gtaaaggctc tcagcgaggt cgtgaaggca gggacggcgg tgatcatgac
    12601 ctcacaatgc ctgagcggta gcgtcaatct caacgtctac gcgacaggaa gggacctgat
    12661 caacgcaggc gtcgtaccgg tcggggacat gcttcccgaa acggccttgg tcaagctcat
    12721 gtgggtgctc ggtcagacaa gcgatatgaa ggaagcggcg aggatgatga ccgagaacct
    12781 caggggagag atatctcaaa ggagggagat cgatggctga gagggtcacc tgcgggattg
    12841 agatacatca gcagttgaac actaacaagc tgttctgctc ctgcccctgc gatctcatag
    12901 aggaggaggg agcgacgatc ctcaggaagc tcaggccttc ccagagcgag ctcggagaga
    12961 tagaccgggc cgtcctggcc caggccgcaa ggaagatgag cttccgatat cagtcccccc
    13021 ggtcgaggtg ctgcctcgtc gaggcggatg aggagcctcc tcacgatgct aacgtcaacg
    13081 cgatgcaggc cacgctcatc gtgtccgaga tgatggggtg ccgggcggtc gacgaggtcc
    13141 acttcatgag gaagatcgtc atcgacggct cgaacaccgg cgggttccag agaacggctc
    13201 tggtcgctat cgacggtgat atcgaaatca acgggaagaa gatagccata cagaccgtct
    13261 gcctcgagga ggatgccgcg aggaaggtgg agaccaaggg ctcagagata acctataggc
    13321 ttgaccggct agggatcccg ctcatagagg tagcgacagg ccccgacatg catgatccgg
    13381 aggaggtcag ggaagtcgcg gttcgcatcg gttcgatact gcgcgcgacg aagatggtga
    13441 aaagggggct gggtaccatc agagaggacc tgaacgtctc cattccgggg ggcgccaggg
    13501 tcgagatcaa gggcgctcag gacctcaagc tccttccgac gtacgtcgag agggagatcg
    13561 agagacagag cggtcttctg aagatcaggg acgagctcgt cgcgaggggc gtgacgaagg
    13621 tggaaccgga catcatcgat tgctcagatg tcctgaaagg atgcaggtca aaggtcattt
    13681 cgtccgctct atcgaagggc ggaaaggtgt tcggggtcgc ccttgcgggt ttcgaaggcc
    13741 tcatgaaaag ccctgactcg aagctcaggc tgggttcgga gatggcgcag tatgccaaga
    13801 ccaagggcgt cgccgggata ttccataccg acgaactacc tggatacggc ataacgcagg
    13861 aggaggtcga cgctctccgg gacaagcttg gcctcgcgcc tggaaaggcg ttcgcgatct
    13921 gcgcggacga aaggacaaaa gcatcatcgg cgttgaagat ggcggccgat agggcctaca
    13981 gcgcgctcaa cggcgtgcca gaggagacga gagacccgct gccggacggc ggctccgcat
    14041 acagcaggcc tctgccaggg gcgggaagga tgtatcctga gaccgacgtc cggccgataa
    14101 cgatcggcgt agagaggctc gaagcgatac gttcttccct tccggagctc ccgggcgcga
    14161 aggcagcgag gttcgtgaag gcatatggca tacacgagca gcaggcgagg cagatcgtga
    14221 aggaaggcta tgaggacctg ttcgaggacc tagccgaacg gtacggcatg gccgccatcg
    14281 ccgctcggac gttcctgaac acgctgccgg agctggagaa ggaaggggtg gacacgtcga
    14341 agataggcga cggcgagatc gtcgaggcct tcgcgtcgct ctcgaagggg gagttcgcca
    14401 aggaggcgct gcccgccgta ctcaaggagc tggccaaagg ttcgaacgtt aaaaaggccg
    14461 tcagttccct gggcatcggc tccatggacc agggggacgc cgccaacatc atagacgcga
    14521 tcatcgagga acgagctgac ttcgtccggg agaagggcga aggcgccgtg gggccgctca
    14581 tgggcgtggc catgcaggaa cttcgcggaa aagtggacgg caagaaggcc gccgacctgc
    14641 tccgggaaag ggtgcaggcc ttcctcagag ggtgagcgtc aacactcgca gttcttcgaa
    14701 gaacagcgtc ttacaggcca cggtccgcac cttccattcc gacagcgctt catccagggc
    14761 cgaggggtcc atgtcgtcgg agacgagcag gagcaccctg ccgtcaggtt ccaggtgctc
    14821 cttcgcctct ttcagaaaac gtgacgtgag ctgaacgccg tcctccccgc ccgcccagca
    14881 caggtcctcc tgcccctgga cgtccccgcg caggtaaggg gggttgaaaa cgatcaggtc
    14941 gaacctgcct tctacgtccg tgaaaaggtc gctttggacc gcttggatgt agagaccgtt
    15001 catcatagcg ctgttctcca aagcctcgat cgcccgttca tcgatgtcga ccgcagttac
    15061 cttagtcccg gccttggcca tgtgcaacga aacgatgccg gaaccgcagc ccatctccaa
    15121 cgccttctcc cctttctcga cgtcgatcgc ggataataga agaaaggtgt cctcagctgg
    15181 agcgtaaacg tcaggatgaa catagagctg aagggagcgg tcgcgcagca cggacgttca
    15241 gcggcggaag gggtaataac ctttcccgaa gggtttaaac cgggacgcta tatcggagaa
    15301 acgtggacct gtacagcctg gtcgccatcg gtctgatatt gggcggacta ctgctcgcct
    15361 acctcaagcg atatccgcta gcccagatgc tggtactcat caacctggcg atattcctgc
    15421 tgtgcaccat cgcctcctgg gattcctttt ccttcctatc ggcggtccag agggacctcg
    15481 gcttccgacc ggactacgtg gaccagcctt ctcactggtt caccgcgttc actcacatgt
    15541 tcgtgcacgc cgacctgttg cacgtgctgt tcaacatgat attcctggtc ctgatcggtg
    15601 ttcctctgga ggagcgcatc gggaggcgca acttcgccct gtgcttcttc atcccggggc
    15661 tactggccct gctattggaa tcagcggtga gggtctccga tcccgagata ctgatactcg
    15721 gcgcgtcagg agcggtggcc ggggccatgg gcgccctgct cttcctctat ccgaaggacg
    15781 agatccccat gttcctgggc ttcatattcc tgccccgggt tccggtctgg atatcggtcg
    15841 gcgcctggtt cgccctgcag gcggtatccg ccttcaccct tccctccggg atagcttctg
    15901 gcggtatcgc gtacgcggcg cacatcggcg gcttcgtggc cgggatgggc gtggcgttcc
    15961 ttctgccctc ggagggggag gacgttccgg acgacgtggt ggacctgggg gacctggcga
    16021 tcacggatga gctacgcaac atcaaggaac gcatcgaaac ggagacggaa ccggacgtcc
    16081 gaagggcctg gctggaaagg ttcgtggagc gttccgtgtg ccccgaatgc ggcgcgcgtc
    16141 cccgcctgga ggggaaccgt atcaagtgca catgcggatg gcagaggtcg gtaagatgag
    16201 cgcgaacagg gtggaggtgc tctgcccggg catgatcgtc cgcgacgggc cggccgtcct
    16261 ggaggcccgt tccaccgtga ccctggtgag ccgtggtgat cgacggttat tggtggacac
    16321 cagtgcaccg gagaaccgaa agatgctgac ggaggcgttg cggtcccggg aactggctcc
    16381 ctcggacatc gagatggtcg tgctcaccca cgcccacggc gatcatcaag gaaatctcag
    16441 cctgttccct caggccaaga tcgtagcgca ccgcgcggaa ggcggcgagc tcgatctaga
    16501 gggcgaggtt attatatggg aaggcgtacg actggtgaac actcccgggc atacgccggg
    16561 cagcatcagc gtgctggtca aggccgaaaa gacgtacgcc atagccggcg acgccatacc
    16621 gaccgaggac aatgcccgga aatgggtgcc gccggggcat cattatgacc ggcgaaaggc
    16681 catggggtcc atggaaatgc tgatagaggc ggccgacgtg gtcgtgccgg gccacgggcc
    16741 ggcattccgt acggctccat acaaggaaaa aggaaggcga ggcgaatgaa cgtaccgaac
    16801 gcgatacaag ttgaatgccc ggactgcggc gaggagaccc tgcacgaggt gctgaaaggg
    16861 agattaggca aggacgggaa caccttggag ggcacccttc gctgccagga ctgcggccgg
    16921 gtgcacaccg ccgtgatcag ggagaccagg acggtgatgg tcccggtgat catcagtgat
    16981 cagggcgagt cccgcaaggc gcagatcgag atccccgagg atgaagtgat ccgcatagag
    17041 gacgagctca tcctggatga ccttccgata atcgtcagct ccgtggagaa gggggacggc
    17101 cgggtcgtga aggccttggc caaggacatc accaccatct gggccaagcg cttcgaccag
    17161 gtgcacgtaa agatatccat caacgacgtg cacaagacca taccggcgga gatcgtggtc
    17221 ctgccagaag aggagttctt catcggggac ctgatgaccg tcggaaggta caacgtggtc
    17281 ataacccaga tcaagacctc ggatggcatg gcccgccgcg gttccgtact ggccagggac
    17341 attgtccggt tatatgccag gaaggcccgc atcacctacg cgtgatgggc atggacgaac
    17401 gccggcagat ggtggccgtt ctgcgcggcc gcggcctaac cttctctaaa agggtcgagg
    17461 aggcgctgct gagcgtcccc cgccacatct ttttaccgga gagcgctcga gccctcgcct
    17521 atcgtgacac ccctctgccc atcggcgacg ggcagaccat atcggccccg cacatggtgg
    17581 ccatcatggc cgaggccctg gaactgcgca aggggcagac ggtcctggag atcggcgccg
    17641 gctccggcta caacgccgcg gtgatggccg aactggtagg tccccagggt aaagtgatta
    17701 ccattgagcg gcatccttcc ctggcggaga gggcagccaa aacaattctg gaggcgggat
    17761 acgccaacgt ccaggtggtg gtcggtgacg gttcgttagg tctcccggag caggcgcctt
    17821 acgaccgcat cagcgtcacc tgcggggcgc cccgggtgcc cctgcctcta ttggaccagc
    17881 ttcgggacgg cggcataatg ctcatcccgg tgggtaacct agaataccag tcattgctaa
    17941 gggtcagaaa actaggtggc agaaccatcg ccgaggacct cggctcggtg gtgttcgtcc
    18001 cactgatcgg tgaaaagggt cacccgtcac aataggaagg gcagcacggc gctcaggctg
    18061 gcgtcccgga ccacgtggtg ggcgccctgt atgacctctt cgtcaatggg attgaacgcg
    18121 atgcccaacg aggccgtctg gaacatcgag acgtcgatgg agctgttgcc tatcgcggcc
    18181 gttctctccg gcgtaacgcc gaacatctcc tgcgcctccc gcagcgatct gcgcttgttg
    18241 cacagttcca ctctaaggac gccctctccg gtcagggtcc catgcgcatc ggcctccagt
    18301 ccgttggacc actgggcgtc gaaaccgtgc tccttggcta tcttttcagc gatgaggtcc
    18361 agcccgccgc tgatgatgac caccttggtc cctcgctccc gcagggcctg aacggtggct
    18421 ccgatccccg ggtttatggg aagccgtaaa agctccctct ccacgtcctt caggttcagg
    18481 ccggggcggt gcttgagcca tagggctatg tcccggcgca tgaactccat atcgtcgatg
    18541 tccccgtcca tgaaggagat gaccgactcc tcgttgctca ccccgaaccg gtcgtgcacc
    18601 caggtccagg aggaaagata atcgaccaac acgccgtcca tatcgaaggc caccaggtcg
    18661 aacttgcgcc cgttctcgct cacgttccaa gccaggaggc aatgattata agaaagttgc
    18721 tccaatgacc agccgatgat agtgctggtc ggtgtcgctc acgttatcga cgtatcgaag
    18781 ccgataggtt ccctggtcga gcattacgct ccgggagcgg tcggcataga gctggacccc
    18841 ggccggtacc gggccttgaa ggaaggatcg ccgcggggca aggtccccat cccctaccgt
    18901 ctgctggcgg tcatgcaaag gcgccttgcc gatcagttcg gcggggaggt cggggcggag
    18961 atgctggcgg ccgtggacgc cgccaacgcc cgaggggcgc aggtcctgtt catagacatg
    19021 gaggccggcc gcctattcaa ttccttgatc agccagatgc cattgaagga acgagtggcc
    19081 ttgttgctgt catccttcgg cggactgttc atgacccgca aacgggtgga gaaggagctg
    19141 caggagttcc aggacaacga ggaacggtac atggagaccc tgggcaagag ctttccgacc
    19201 gtgaagcgcg ttctcatcga cgaaaggaac gagcacatgg cccggaacat cctgagggcg
    19261 gaggggcagt acggaagtgt gctggcggtg atcggcgacg ggcacgtgga aggcattcgt
    19321 cgcatattat cgagagagga cctggtggcc taccgcctca aggacctgaa cgacctgcgt
    19381 ctagagcggc cggtcagcaa cgccgaggca tccttctcct tcaccatcgg gaactgaggg
    19441 aaatcctttt tctccggatg gcatatccca cccgatgaag gtagttcttc tttcctacac
    19501 caacgatgcc gagaggcttt gcgccgcggc cgcccgctcc tgctattcgc cggacgcggc
    19561 gagcgagata ctggagggcg tggaggagga caaggccgga gccttcatcg acaaggtggt
    19621 gggcatgggt caccactcgg tcatcgagca tgcctcttac accttctcat tggaaggcgt
    19681 ctcccgctcc ctcacccacc agctggtccg gcatcggata gcgagctact cgcagcagag
    19741 ccagcgatac gtatcactgc tggagccgga ctacgtgacg ccggagacga tacgcgccga
    19801 tccgaaactg aacaagatgt tcgaggaggc catggagaag gcctgggaag cttaccagaa
    19861 gctggcgacg gtggtcccgg tggaggacgc tcggtacgtg ttgccgaacg cctgcacgac
    19921 gaacatcgtg gtcaccatga acgcccggga gctgtggcac ttcttcacct tgcgcacgtg
    19981 ccgcagggcg cagcaggaga tacggaccgt cgccgagctt atgctcactg aggctaggaa
    20041 agcgtcaccg accatcttcc gggatgctgg tcccgcctgt ctccggggaa agtgtccaga
    20101 agggaagctc agctgtggca agccgcgcac tgagctaaga tttaaataac tccaatactt
    20161 tggccgcatt tacctgggaa gattgctatg ggcaacatca gaccaactta catcaagaga
    20221 gtggccgtgg aactggtcga gaagtacccc cgcgctttca gcgccgactt cgagaacaac
    20281 aagatcctgg tccagaggct caccaacgtg agctccatca tgatgaggaa ccgcatcgcc
    20341 ggttacgtca gccgctactg gcagaacaag gacttctgaa actcttaggt tcgcgcctct
    20401 tggcgcgacc gtcgtaaatt cttcatcttc tatccgcttg ccgctttttc gattcaacta
    20461 ttggcgaaca ccacgcctgg caaaggtatc ggtgatcctt tgggccggtc cggggagtaa
    20521 caacgcttta gtaattggag catattctcc acaaaatagg cccgggtggg gtagcttgga
    20581 tatcctaaga ggctgcgaac ctctagaccc ggattcgaat tccggcccgg gcgctcttct
    20641 aactacaggt tcataccgac ggtctccttg atctccaggt cccccggcgg tattatgcgg
    20701 gatatctcct cctccggcac gccgaacgcc ttggccagca tcgaggcggt ctttcctctt
    20761 ggcaatttgc cgggaactat gaccaccatc ttctccgagg aaatgctctc ccgaggggcg
    20821 caggatatct tccgcgagcc ttccatcagc acctcggcga tcaccatctc caatggcaga
    20881 tggtgctcgt aattgcgctt cccgcggatt atgaaggccc cgcggggggc gaactctccg
    20941 gcttccggag tcttggagac ctggtccggc aatacccaat acgccgttcc ctcggcggct
    21001 ccggcgttcc aggccttaga gtggcagagg gcgaactgac acacctctcg cagttcctgc
    21061 tccgtggcgt ccgcgccgtc cttaaggacg atggacggag ccccgtggag gtcggcgtga
    21121 gcgtagcgtt ctcggtcccc cagatgcttc ttgaccacct ggtcgttgga cttggcgtcc
    21181 ctccctccca ggaccaggcg tccattggag gtgatgaacc acttatacgt ctcgaaccag
    21241 aagcgcttgg tgggcagcat gcgctccttg gcctgctggg cggccttggc gcccttgacc
    21301 tcccgtttgg cgatggccgt cctggtctcc tccaaagctc ccttggcccc ggcggccttc
    21361 tcccgcatct ccttggcctg cgaataaagg cggttggcgt tctcgtctat ggccacggtg
    21421 taatcgagcg tgaccttctc ctcgcccagc ttcatgacga agctcttcct ctgcggttcc
    21481 accgagatca ccagaggaac cttcgctccc tgctccatga gcttctccca gctggtgttc
    21541 ttcgatagcc cgttcatcct ttccaaggtc ttggagacct cggcgtagct ggtgtacagc
    21601 atatcgccat gggactgcag cgtggccgcc tccctctccg tggcctcgat tcccttcaac
    21661 tgctggtcca gctgcctctg cagcctctcc agctccgggt cgaccttgac ctcgtcctcc
    21721 ttcttttttt ctaggaacgc cgagatggcg gccgatagcg tgggcatttc ttgccgttcg
    21781 tatccctcat tgaccatcag gggatagggg gtggcgtcga tggccgcctc tccatcggac
    21841 accaaacagg cgaactccct ttcccggagg gcctcgaaaa gaccaagggt ggccgaacgc
    21901 aatgaggcga tctcctcctc ggtcatcccg gaggcctttc ggtccttgtc cagaccggtg
    21961 cgcaggcaga tctcctcccc gtactgtccg cccaggttca ccgaggtcgc catggttcga
    22021 accaggtccg acttggaggt gagcacggcg gtctggaact cctcggcgga agcggtccgg
    22081 ggatcgaacc gcgagggcgg ataggcgtaa tcggctccga tgagaacgtc ccggtgcctc
    22141 cagcgcttct gctgcagggc attgatgatc ttcccgtcgt tcaccattat aaggttgccc
    22201 tcgcctatca gctcgaagat gagctgatac gtcccgtcac gatcggccag accgatggtg
    22261 actatgcgat cgaactccct ctgggagacg gacattattc gggtgttgta gagcacctta
    22321 cgaaggtgca ccgcgaatcc cgacggcgtg tcgggcgtct ccgggcgatc ggccacgaag
    22381 tgcagccact tgccgtccct gagcaccagt tccttcttgc cctcgccctg cacgtttatg
    22441 cgtagcagca cgttgcgacc gtcccattgg aatatcttgt ccaggaagcc tccgaccagc
    22501 ccctgcatct ccgacgttat ggccgccacg tcgaaggccg tcatctcctt cttcatcacc
    22561 acctctagcg ccccctcaat caaaaggatt ttgcctacta ccagtagcaa aaggtttatg
    22621 aacgaccacc ggtttgtcgg tggagcaggc cactgtggct tagaggtata gcgacgcctt
    22681 ggtaaggcgt aggtcggggg ttcaattccc tccagtggct ccatatcctt ctcaacaaat
    22741 attgatgacc cagcatttcc accggctagg acatagtgga gcgggggacc aggtccagaa
    22801 caatgtcatt agcggttctg gtacgtccgg gcgaccgtcg gggagcaggg ggcgctgacc
    22861 aacgtcaacc gcagcttcag cctgatactt tctccggggg ccacaccctc aacatgagca
    22921 gggatggaaa cctggacaag atggtgatga tgcacgtggg gcccggtggc gacctggtcc
    22981 tggggaattc ggtcctttag gaagctcccg cagatgaaat actgggcggc ggaaccatgc
    23041 tctatgtggt catcgccgtt ctggtgttgc tcgttgcagt gatcgccttg gtgatcctgc
    23101 gccgcaggaa gtaggtcacg ccatgcggta gtacacgaac ccggaccaca tcttcggcca
    23161 gaagtaggtg gacttcttgg gcatgcgtcg gtccaggcgg gccagttccc atatcatgtc
    23221 caccgagggc gacctcagca tgaccatcag ccgatatcct tcggacatct tggccaaagc
    23281 tttcgcggtg tcgtgctcgt agaacaccgt cggctcgtcc ttccaggcct ctcctttcag
    23341 cacccattcc tgacacacat aggagtccag ctcccacatc tcatcggccg gcaggtcccg
    23401 gggagaggcg acgtaggcct tcccttcgat caccaggccc acgtcagacg acggtcgtcc
    23461 ctccagggcg gaggccagtt cggaaggttc agaaacatcg aacaggtcga aacggctttt
    23521 cacgaactcc aggaacgatt ccgcggacgc aggcagctcc ttcaccaaac ggtgcgtcgg
    23581 gaagaccagg agcccagggt cgttggacgg caccagggtg gccagcacga actgcttctt
    23641 cggggagtct ggattttctt gggcgtagcg ggaggacgtt tcgtagcggt ggtgcccgtc
    23701 ggcgatcagc accgtcttcc ccttcagctc cgccattatg gattcgacgg tctccgggtc
    23761 gcacacgcgg aacaggcagt gccgcacgcc ctgggggtcg gtgaactcca ggaccatggt
    23821 ctcccggtca tcgatcctgt ccttcagttt ggccgaaagc tcatcgaata tgccgaatat
    23881 cgactcgcaa tgcgtctccg tgccgcgtaa aaggttcagg cggtcctcct tgaccttggg
    23941 aaaggtctcc tcgtgaggca cgaccccttc cgcgtatcct ttggcggcca gcaacccgat
    24001 gatgccggtc ctctgccaac aatgctctcc ctcgcagaac gtctgcttgt aggtatagaa
    24061 cgcatcgcgg cggtcctggg ccagagcgcc atgctctatc caggagcgca gcgcttcgcc
    24121 agccgaggaa tagttaccgt cgaccccgcc catggtcacg ttggtcacgt tatagcggtt
    24181 ccccttgagc ctggccagtt catcggcgga gatgacatcg taaggagggg acacacgctc
    24241 gatgatcccc tcaccattct cgagacgggg gatgtaggga cggaacggac ggaaatcgac
    24301 catgaccagt catcgctcta tccgataata tcttttacaa tcacttcagc cggaccagct
    24361 cgtaatcctt attacccagg ccgatgcgtt gggcgtggtc catcccggtc atccagtccg
    24421 tggtcgggtg caccgacctg aacttatcgc ccttcctgcc cttcacgtcc aggacgctcc
    24481 ccttcaccac cgaggcctcg ttcaccaggg tgacgcaggc catgtccaag gccaccgggt
    24541 ccttggacgc cgcgatgccg atgtccggca ctatcggaac atcattgaag ggccagcagt
    24601 cgcagttcgg cgagacgtcg gttatcaggg agatgtggaa ggacggtttg ccgttgacca
    24661 ccgcgaaggc gtactcggcg atcttctggt tcacgatctc cgaggagccc tcccattcca
    24721 cctccggcgc tccgtaacgg caaacggcga tgcattgacc gcagcccacg cacaggccgt
    24781 catcgatgac cgccttcttc ttgccggtga gcgttatcgc cttttccggg cagttcttca
    24841 cgcactgtcc acaacccacg catttcttgc tgtccaccgt aggatgggag gaggcgtgca
    24901 tctccatctt gccgcagcgg ctgccgcttc ccattcccag gttcttcagc gctcccccga
    24961 agccggtgag ctcatgacct ttgaaatggg tcagggagat caccacatcc gcgtcggcga
    25021 tggcgctgcc tatcttggcc gtgcggcaca gctccttgtc gatcaccacc tcccgctgct
    25081 cgttccccca caagccatca gcgatgatca cgtcgcagcc cacggcgatg cggttgaacc
    25141 cgttctccat cgccgagttc agatggtcca cggcgttggc cctctttccc aggtacaagg
    25201 tgttgcagtc ggtcaggaac ggcttgccgc ccttctcctt gatcatcctg accagtaccg
    25261 ccgcgaagtt cgggcgtacg taagcgagat tgcccggctc gcccatgtgc agcttcaccg
    25321 cgaccagttt tccgtccagg tccatcttgt ccaggccggc cttgcgcagt agcttttcca
    25381 tcttctgcag caggttgctg ccctgacagg tgtgcatgtc ggtgaagtag accttggagg
    25441 aagccatgcc cctgaatcag catgaaccga tttaatgatg accttgccgc ggctcgccag
    25501 tcgcccgggc ggtgacctcg atccagttca ggtggtccat acccttctgg tccttgaagt
    25561 ggacctcgcg aacgtccgag cgtacggtta tgtcgatggc gcctgcccgg tcggccttcc
    25621 cccggacatg ctcctccgcc agctccctgg cccttcttat cgtgtcctcg gccctccgga
    25681 agtcctggga gtctccccat ggcgtgacca gctggaactg gccgtcgctc aggggctgga
    25741 tgcgtaacgt gagcgtttcc gatattcgcg agcacaccgc gcccacggca ttgccgaccg
    25801 gccctccctc gggaatgacc acctccgcgc cgagaagatc gcgcagggag ggcatcagca
    25861 atcgtgacgg tcctccgata cccacgatcg ggcggtccag tcgaatgccg atgtggaacg
    25921 aactggaaga acgttcgccg gccattagct gcaacagtcg gtctaccgtg gcgtccttcg
    25981 gcaggtcccc gatctcctcg gccaccacct tgcgtacgat ctcctccgca agtcttccga
    26041 ccatgcgatg catgacccgg gcgcagtagg cctccacgct cattcgcgtc ccttccagat
    26101 agtgctctac acccgcgcgg gacgaggcct cgtcgcctat cacgtacaat ccttccaggt
    26161 tgaaaatgtc ggtaggcgtc agcccggtcc tcagcagatg cccggagtgc accagctctc
    26221 tggccatctc cctgaccagg taaaggtccg ggagagcgga gcgcagctcc tcctcgtcgc
    26281 atagtcccag ttcctccacc ctgtgataca cctggagctt gctgcccgac agccgctctg
    26341 ggcctcgggc ggtgacgtaa aaatcagttc ttcgccgctc catgatcatg cgcggcagat
    26401 ccttcgtgcg ctcaccagcg aatgccaacg gaagcaccct ggtcggccct atcctgagat
    26461 ctccgtgcat gtccgaaccg atctccgaat ctccgcccag acccaccgtg gtggcgtcta
    26521 tggaacgaac gcgtgttcgc catccggcca gctgggctcc ctcgcgaccg atgcgcggga
    26581 aaccgttgtc gatataggcg atatcggtgg acgttccgcc catgtctacc accaggcagt
    26641 tgtccagtcc ggagagacgg gaacctccga gaagggaggc ggccggcccg gaaaggatgg
    26701 tctccaccgg tctttccctg gccaacttca ccggcatcac gttgccatcc cctttcagca
    26761 ccacgatgtt cgccgcgatg cgcaggacct tcatcgaaga ctcgatgcgg tccaggaagt
    26821 cggagatcac cggtagcagt cgagcgttca gcactgcggt gacgcttctc tccaccactc
    26881 ccaattcccc gctgagctcg taggccgcca ccaccggccg ccccgtcacc tcccggatga
    26941 gctggcgggc ccggtcctcg tgactgggct ggtacacgct gaacatcgag gaaactacga
    27001 aagcgtccac ctcctcggcc atggacatgg cgatctcgcg cagctttttc aggtccagcg
    27061 agtccatctc ccggcccttg ctgtcatgac cgcccttgat gaaggcgcaa ttctccgccc
    27121 ccagggagtt cacgtcctcg atgtcccagc cgatgccgat gaggccgacc cttcctcctc
    27181 tggattccag gaccgagttg gtggccaggg tggtagacag tccgaccagt ttgatctggg
    27241 tgggatcgaa tcgttccttc ctgagaaggg acctcacgga actctctatc ccgaccgtca
    27301 ggtcctgggg ggtggtgggg ctcttgctcc aggcgaggag ccttttggtg ctgaggtcga
    27361 ccatcgccgc gtcggtgtac gttcctccgg tgtcgatccc caaacccagc tccatggtcc
    27421 tccgaaagat gtcagcgttc ctataactat tcgatatctc cgctaggatt ttataaatcc
    27481 tgctaccgct cttttcgttc cagcaggtgt tcacatgagc ggagggcacg ttcaaggcga
    27541 caagggcacg ggattccccg acaagctgag cgcgctcatg ggcgagctgc gtgagcagtt
    27601 cgtggaaagg gaggaggaga tcgccggagc gctactggcc atgctgtccg gggagcatgt
    27661 tctgttcatc ggcccgccgg gaaccgccaa gagccagatg gccaaggtga tgtgcgagag
    27721 gttgcgcggc ggttctttct actattactt gctgacccga ttcacatctc ccgaggaagt
    27781 gttcggcccg ctatcgctca gttccctgca gaacgacgag ttccgacgcc gcaccgaagg
    27841 ttacctcccg caggccaaca tagcgttcct ggacgagata ttcaaggcca actcgtcgat
    27901 attgaacagt ctgcttacga tcctgaacga gcggaagtac cacaatggca acgaggtggt
    27961 ggacgttccg atactctccg tctatggcgc ttcgaacgag cttccgaacg aggaggaggg
    28021 gctggcggcg ctctatgacc gttttctgta ccgtttcttc atcaccaacg tccaggacga
    28081 gggaaacttc ctgaaggtgc taacgtccag caacggaaag gcggccacga ctaccgtcgg
    28141 gctggaggac atcgaacgca tcaaggacga cgctcgatcg gtgaaggtcg acgaggaggt
    28201 gctgcaggcg tatctgagcc tgcgcaagca cttccggtcc cagagcgtgt acatatccga
    28261 ccgtcgctgg aacaagacct tgctggtgct gcgcaccgcg gccgcggcca tgggccgggg
    28321 aaacgtcgac ctgacgttct tgccgctcct gcagcacatg ttgtgggacc gtccggagca
    28381 gaaagaggga ttgagatcat tgctgatcga tctgaccagc agcggagggg tggacctccg
    28441 ccgtctgcag tccagcagcg aggagctgct ttcgttattg gctaaggcga agcagcactc
    28501 cgcctccgac gtgcagttcc cgaggccggt gtgctgctac gactgcggct cgacgttcat
    28561 gagcgccaag gagctttgcc ggcacggcga gtccttccct aagcatctgt acatggaccc
    28621 ctacgccagg gaggcccagg gcgtgaaccc ctcctaccgc aagttcgagc tgccggagct
    28681 gatgcacgtg ctggagaacg tgcgcggctg gaaggtcacc tgcctgcgcg ggggcgccga
    28741 acaaaggctt tacgccaggg agctgcagga cctgcgttcc gtctacgata aggtgagagg
    28801 ggcgcacgag atggaaaggg gcgagctgcg caagcgtctc gacgggaaca tctggctgag
    28861 caagagggac cgccatgaca tcctttccag gcaggaccgc cgcctggagt cgatggccga
    28921 gatcgagcgc tccctaaagg aagtggaagc ggagctcaag gagtgatccc caaccgatga
    28981 aaggccttat ccgtgaactt ctggagaggt cggaggtcca ggagatactt atggctccga
    29041 gctcgattcc tctggaccac agggatatgg ccgcggcgct gatggcttcc gatctcttgg
    29101 gcgatctcca gagcttggaa cccatcgatg tcaccaccat ggtcatccat tcccttttcg
    29161 aaagcaaggc ctgggcggac gctaggaagt tggccaaggg ccagccggac ctggtgccgg
    29221 aactgctggt gctggcgctc cctaaggtga tcgaagccat ggccaatggc gtggggggat
    29281 tggattggag cgagctttct gaggaggagc ggcgcagcac cgaggacctt ctggaagcgc
    29341 tattggatgc cgaaggacga ggcggtgagg aggtcgagct ggacgagcgg cagagggaag
    29401 cgctgaagct ggtgctcaga atgctggtga ggtccctgga ccgcagcata gcgccgctca
    29461 tcgacaggct gcagaaggat tccgaggtgc tattgcgcct ggaggagctg cttcccggcc
    29521 agggctggga cctgcaccgg gtaggattgc accgggccaa gctcggaaac ctggaacggt
    29581 acgcctccat gcttcgaaag cacagggacg tggatcgcct gaaggagctg ctggggagga
    29641 tggaaggaga taaggaccgg agggcgtcat ccgattcctg ttcgttaacg gaaacccact
    29701 ccctgatctt ctccggcgat gtgcagcgca tgctgcccca ggagatggtc aacctggccg
    29761 acgaacgatt gaagctgctc ttctatgccc ggatgtgcga gcggcgcttg ctaacgtacc
    29821 aattgagagg gaaggagttc cgggacgggg agaggaagcg gggcggtcca gtggtggcgc
    29881 tgctcgattc gtccggctcc atgagcggcg agccggagat ggccgcgaaa gcgctgttgc
    29941 tggcattggc caggcgtcta tcggaggaac ggcgtccgct acgcgctttg atgttctcgg
    30001 tggatgtgga ggcttacgat ctgtatgatc atagcggacg gtcccagttc ctggagttcc
    30061 tgtgccagac cttcggcggg ggcactgatt tcgatgccgc gttgcgtcag ggcataaaga
    30121 gcctgagcga accggaatgg cagggggcgg acatcctctt cataacggac ggtctggcgc
    30181 gcataaagga ccggggctgc ctgcacgact ggaaccgcct gaaggaaaga cagggatgcc
    30241 gcatcttcac cgtgctggtc ggggggacgg aacccggagg tctgcagagg atatccgacc
    30301 aggtgttcct catgaccagg cagggcgagt ggtccggcgg ttcgctattg caggaattta
    30361 ctcctcaacc gcgctcgatc ggctcctgct gggtcacgca gtgaatgccc ccgtagccgt
    30421 agaccagctc ccgggcgacg atgggaacga tctcccggcc cgggaagtgg gaggacatta
    30481 tttccacagc caccttgtcc atggggtcct cgaacaccgg caacagcacc accttgttgc
    30541 cgatgtagaa gttggcgtag ctggccggga ggttgcggtc ctcttcctcc agatacagag
    30601 gctcaggcat cgggaggcgc tgcagttcca gtccgaagcg gtcctgggcc ttctctagca
    30661 aggaccagtt cctctccagc accggggcgt tctcacctct atcggagaag gcgcagagca
    30721 cagaggtcgt ggacgagaaa cgtgcgaagt cgtctatgtg cccgtcggtg tcgtccccct
    30781 ctatcccgga cgccagccag atcacgtcag gcgtggcgat gtactgctta aggtaatcct
    30841 cgatccgaag gcggtccaag ttcgggttcc ggttcttgtt caagaggcac tgctcggtcg
    30901 taagcaccag accttttcca ttcacgtcta tggaaccgcc ttccatgacg atcccaggct
    30961 tgaagtaggg aacgcccgag ctctccacca catgctgtcc ggcgatatcg tcatacagca
    31021 ggtcatcgta cttggcgccc caagcgttga agtcccattt caccgccgcc ttcttgccgg
    31081 tgtccttatg caataggaaa gaggggccgt aatctctgat ccagacgtcc gcgctcttta
    31141 ttcgttcgaa acggacgcgg gacatgtccg ctccggcctt ggacaccttg gcgtaggccc
    31201 tttcctccag ggcgtcatcg tccaccagta tcttcaccag ctctcccgag ctcaacgcgg
    31261 cggtcatttg cgcgaagacg ccttccacct catctatcac ttcctcgggg aaggtcaacg
    31321 ggttcttagg ccaggagagc cacgttgcgt catgcttagc ccattccgca ggcatgcgat
    31381 atcctttgga caacggtgtt cctttctgca gagccattct cattcctctc ttttctcgac
    31441 gagcgccccg tagcactccg ggcggcggtt atggaagaac ctccagccct ctctgacgcg
    31501 tttgccgtgg tccatgtcca cctcagccac aagtacctcc tctcccttcc ccgctcgagc
    31561 caaggtcttg ccgaaggcgt cgcagacgaa ggagccgccg tagaactcgc tatctccctc
    31621 ggtgcctaca cggttcaccg cgcataccgg aacggcgttc gctatggcgt gcccgcgcat
    31681 aacgttctcc caggcctcct gccaatcgcc ttccgcttcc ccgatgcccc ggaccgtgcc
    31741 gatggccgtc gggtaaaata tgatctccgc tcccagaagc gcgcagcatc gagccgcttc
    31801 cgggaaccac tggtcgtaac atatcagggc ggagacctta ccgcaggagg tcgggaacgc
    31861 ctggaaaccg gtatcgccag gcttgaagta atcctgctcg taaaagcact catcatgcgg
    31921 tatgtgggtc ttgcgatatc cccctagcat cttgccgtcc ttctcgaaca gggtggcggt
    31981 gttgaacagc ccgtcctccg ccgcctcgta gatcgaaccg ccgatcacca ccgtagcggt
    32041 ccgtttagcc aggtccgaca gggtctccgt gaccagaccg gggatggtgc tcaggaatcc
    32101 tccccgttcc ctctttcctt cggggtcctc ctctctcggg aagtaggggg tggtgaacag
    32161 ctcagggagg cagatgatgt tcgctcctcg cgatgccgct tcctcggaca tgcggacggc
    32221 cttctccagg ttgtccgtga catcggaaga catggccatc tgcaccagtc cgaccttgag
    32281 catgcgttct ccgggcatgt tcagccgatt agggccgcga tgatataacc gttactctta
    32341 gagcggatgc aaccgacgta tgcgctccag ggaccattcc gcccccttac gtaaaaattc
    32401 gctattttca aggagcatgg cctccagaag cgggacggag gagggtgagg tcacccgcat
    32461 cttgtcggcc atccggccca aggcccaggc cgccatgccc ttcacctccc ggtctgggtc
    32521 ggtaaggagg atgttaaggg cctctatgga tatcgtatcg cctatgctct gcccggccag
    32581 ctcaccgagg gcccaggccg cgttggaccg cacctcttcg tcacgatcag tggtgagcag
    32641 gatcaggctt ggcaccgagc ggggatcgcc gatcttcatc tgagctagct tcccgatgca
    32701 ccaggacgaa tcctttcgca cctggtcgtt ctccacttcg gtcagtggga tcaatgcttg
    32761 gagcaggcgt cgatcggccc agccggccat caggagctca cggctgtcct ccaacgccgc
    32821 tcggcattcc tcgacgttaa gggaccgcag tcccctgagg atcccatcca gctcgatgtc
    32881 caccactttt cttcagctcc tgagggcaga tcagcacttc gggaccggtt tcagcttgta
    32941 gaactcgcag gtgcggtaat cttcctggcc ccggcattcg ccgtaaatgt ccttcatgcc
    33001 cagagcgtca aggcgatagc gtctcgcctt gcagttggcg catctgttgt ccggcgcgtg
    33061 ccacaggcac ggtcctttct cggtctcttc cgccatgtta cctagtcata atattcgttc
    33121 gtatatttac gatgtatctg ttctgaaaaa tttcaaaaca gggcgacagt tcgttcggtc
    33181 aaggacgctg cgcacaagat cgccttgaat ttcatcagaa gaagtcgcgt caccagaaca
    33241 ttgggatggg cccagccgga ttcgaaccgg cgacctactc cgtgtaaggg agtcgtcata
    33301 accgctagac catgggccct tcggcttcgg tcattgttca gggattataa aaaggaaaag
    33361 gaaaaaatgg tctggaaggg tgcggcgggt ttttttctcc cgaaaaggat ttagtaagcc
    33421 tccattatta aagaggacgt taaacggtga tggtcacttg gccaaaaatg atggtaaagg
    33481 ttcctggttc aaagaggcca tgagcctgcc ggaaacaggt ccggcgttgc gcagatattt
    33541 cgtgaacacc atgttcgaca gcacgttcgc cgtgctgggc atcatcatag gttcagccct
    33601 gaccgccgac gcggattcag ggctggtcat cgccaccatc atcaccagct gcgtcgcttt
    33661 ggccatatcc accggcagca gcgtctacga aggggagacg ctggagcagt ctcggcgtat
    33721 ggacgagatc ggccgggcca tgctgcgccc ggtggaagag acgaacttgg gtaaggcgtc
    33781 caaggccagc gcggccatca tcgccctctc gaactccctg gcgcccctga tgagcggagc
    33841 gataatagtc tctcctttcg tgctcctggg cgatgagacc atcctggtcg cggcggaggt
    33901 ggccatcgtt ctggcgatca tcctgttgtt cataaccggc tttatcatgg gcaagatcag
    33961 cgagcgcaac ccctggtgga aggggatgag gatggccctg gtcggggtgg ccgccttctt
    34021 cgtctgctac atgatcggcg gcgcggtgtg aactacggtt tcctcagcaa cacttcgtac
    34081 agcttcttgg tgaagggcgg ggaggggtcg tcaaactccc ttacgtgcac gatatcgtaa
    34141 cctctggaca gtctcttgat cttgtcctcg gagaagtagt ggaccacgaa gccgatgggg
    34201 ttctgccaca tgtcctcccc cttgtgcgga ccttttccga aatgcgggtc gtggtcgtta
    34261 cgcaccgagt acaggttcaa tccacccggc ctgagcactc tgcggcactc gtccaatatg
    34321 aactggatgt ccttttccca cagctccatg gtcagcagca tgtgcgagta caccgcgtcc
    34381 accgagccgt ccgggagcgg aattccggcc cggaggtcct ggcacatgca ttccatgttc
    34441 ccgtccaggc acatctcttt ggtcctctcc ctcatctggc atatgcccga atcggaatag
    34501 tccagggcta tgacctggaa accctccttg gcgaacaggc aggtgtcccg accctggccg
    34561 catcccagct ccaggacctt gcggcagccg ttcttccgga atatgtccac ggcccggacg
    34621 gccaggtcgc tcggctcggc tccgaagaag ttcggtttac tggagtacgt tgagttccac
    34681 tgcttgcgct gctcgccctc ggacatttta cgatcctata atgacttggc cctggatttc
    34741 gggatcgcac cggcgcccat ggtctttacg gtggccacta tcttctcgaa gttcttgaac
    34801 gggatgccga tcagcatctc ctcggccatg atgtcggtcg tcttgcggca gccgaagcat
    34861 cccagggata tgttggtctt gcccttgact atggggatga cggtggcatc aacgcaactg
    34921 gcctgaacgg cggccatctc cacggacacc cttcccccct cttcgtaggt ctgcgcggca
    34981 gggatcagcc agaacacctg ctccggcaag gcggtcagga cgatgacgtc agggaccagg
    35041 gtggccttgt ccaatggagc ggcggcgacg ccgatgacgt cacccaggtg gaacgacgtt
    35101 ctcatctcca gggtctgctt ggccgcggcc gggtccttga acattcccat gttagcgtgg
    35161 aactctccgg acgccacctt ctccggcacc ggtaccatgc ccagagcgga cgcccccacc
    35221 gggcaggcct ccttttccgg ggtcaccaac agcttctcgc ccttgcgagc cctcatgata
    35281 gttccgcagt gcctgaccgg ggtttcggtc actggataat ctgatggaag ggcatgtcct
    35341 ttcttgatca aggttatcgc aactggttca tgcttcaagc ccaaggtttc cttcagatcg
    35401 cgtgccatcg cagcatagtc ggacataaaa ccaccaaaca aatagcgata ttggccgtta
    35461 atataattat ctatatagca tataaaatat aataaattaa taataatata tttggtcaga
    35521 aagaaaaaaa caaccagctc agcagatcct tggcaccggg tctcccaccg gtggctccag
    35581 tatgcggcgc ccgccgacct cggtcctcat catgacgtgc ttgaccgcct tgctggcgtg
    35641 accaacgatg gccgcgttcc gaccgtgctc gtccgagcga agcgccttca gaacttcctc
    35701 ggccatctcc ggcacgcagg ctatgacgac ctttccttcg tttccgatgg tcagcggatc
    35761 gaggccgagc atctcgctgg cgttcctcac cgcgtccgcg accgggatgt ccttctccac
    35821 cagctccatg cccaccttcg acttggagct ccattcgttg atggcgttgg cgaagccgcc
    35881 gcgggtggcg tccttcatgg cggttatccc gccgacctcc agcagctttc cgatcatgtg
    35941 gtttagcggc gcgcaatcgc tctgcacctg gctctcaaat ccgtatccct cgcggaagga
    36001 tagtaaggca attccatggt cgccgagcgt tcccgacacc agtatgacgt ccccgtcccg
    36061 gacgttgtcg tccgtcagcc atctggagtc caccttgcgg taggacgagg cgatcttcag
    36121 gttgtggtcc atggccgggt ggcgcttgcc gacagcggcc gcggagatga ccattctctc
    36181 gatcgctccc ttttccatga cctttgtatc gccagtaacc accggcacgc cggccatctc
    36241 cgagtaacgc ccgatgcttt tggtcactcg ctccagcacc tctatctcca gcccctcctc
    36301 cagtatcatg gacatggaca gcgccaaagg tcttcctccc atgaccgcga tgtcgttgac
    36361 ggtgccgctt acggccagag aaccgatgtc cccgcccggg aagaagatgg gttttacagt
    36421 gtgaccgtcg gtggtgaaga tgatatcgtc aactatagcg gcatcgtcca tggagtccag
    36481 ggggacctcg atcttgatct tgggaaagaa cggggcgatg gacttggaga taagttcctg
    36541 catcatctcc ccgccagccc catggcccat ggtgacccgc ttcatgagtt gccgaagaag
    36601 gaggcaggtt attaagattc ccaaaagtcg atgcccggga agggaggaat agttttaatt
    36661 cccccgttcc ttatgcgcca aggcaggggc tcgtagggta gcctggatta tccttttggc
    36721 cttcgaagcc gacgactggg gttcaaatcc ccacgggccc gccatcatcc taaccatcta
    36781 tgaaagccaa cctggtcaat attcggtctg taagaatttt gaatcaggtt tacaaatttt
    36841 taaagacaaa cgatcataca atagcctggt cacttcaatt aaaaaagttt catccaatag
    36901 ttatttaagt tcgtacaacg catttgttta acagagacgg cgagaaggtc aatgacccat
    36961 cattgaatgg ttacgagccc ttctccttgg tctcttatct tttattgata tctatttcgg
    37021 tctctggatc ggtttgaggt gttcgaatga atgttttcta acaaggtcga aagcgtcctg
    37081 ctccttctgg ttcctataat attgcctagc cacaccactg accatatcgg ctatctggag
    37141 gccaggaatc ctgttgctcc tctcaaaatc aaaggaaatt gttataccct tgtctttcaa
    37201 attgtccaat atcatatatt tgcataattc cagtgctttt ccccaaacct cggagtctag
    37261 cacgacgccg acttcaaatt ttccattttt ctgaaatgtc agcaacggtc ggagattgga
    37321 tacgatcgaa cgagctctga tccaatttcc acacggttcg ttcccgttgg cgatctgatg
    37381 ttcgaactct ggagaaaagt cgacggttct ccagcacaga ggttctttta gaattattcc
    37441 atcacctctc agtatcgagt tgtccgaatg ggacgcatgc aacgcggtct caagcaaggt
    37501 agccgatatc tgccctaatc catcggaatg gtgaatttct tttttttgac tttttaagaa
    37561 cgaatttgca acgggtttca ttgcgtctat ggtatatctc aacgcattct gtgctcctct
    37621 ggttgttgaa ggacagcacc acaccgaact tacagtaaaa acagattcac tagcatcggt
    37681 cataccgctt tcgtcaatat ataccaggac tctggtcaag tgacggcaaa taactgcgtt
    37741 ttattaatat agattctatc tggttctcta aaagtggacg cattagtttt acccggtctt
    37801 cttgttaccc cacccatgtc aacatggcca ggtccgtcaa tgatgtgtgc gccatcacga
    37861 catcttattt ctagcgtggg tcacctggtc caagcgatcc gatatcagtc ctcgtagaat
    37921 cgctcagtct aattcttaag attggtgcgg tctcatcgga tgaagttcat tcacattctc
    37981 agcgatccgc ggaacccccg ggagctgtag aacgaggggg cgctgttgtg atatacgaac
    38041 acgtgtccgt aacgccgatc cgcgaacagt gctcctccga gggcccttat gttcgtcggt
    38101 gtcctgatcc agctggacgt cttcgtgtcg aagctttcca gtctctgtaa atcccggtac
    38161 tgttcctcgg tcagcagctc tatgcccatg gcggccgcca tgcccaaggc gctaccggcg
    38221 ggatgcacgc ccttccgctc cctctcctcc agaccttcct ggtcgtaaca gacgctccgg
    38281 cggtccttgg ggctctcctt cgaacaatcg aagaagatga aagcgccgga cgagcgatcg
    38341 caaccgacca cgtccggctc tccgccggtc ctctccatct cctggagcga ccataatcta
    38401 tctggatcgg cgttcagcct tgcttgtacc ttgctccaat ccaggtcctt atggcggctc
    38461 tggttctcct cgaaacgggc ctgcaagacg gccaagaggg cctctcgctg ctccgaggtc
    38521 agttccttca ccatctcctt cgccatggtg ctttgcttgg aagtgcggac agataattat
    38581 ttctcaggcg ccaataacgc cctcgttctt tcctttccgc cggtcaatag acagtggtaa
    38641 ataagtaggg gaagcgcatt gacgaaatcg aacatatccc tagggggtgg catcatagac
    38701 ggcatgatac tcataatcgc accgttcctt cctacgatag tcctcttagc cttggtctac
    38761 atgaccttga acaagaggaa gaagaaggaa ctggcagcca agaaataggt ctctgaacca
    38821 gacctcggtc ctttttttag atccgaccga acgtcagttt atggcttatc aactatgctc
    38881 gtcggaggat caggttttcc atcctatcta ggaaacgatt atctcaccct ccttcgttcc
    38941 acccgtcatg gcagataact ggaactggcg cgatgatcgg ataccccgga ttgacggaaa
    39001 acgggtcatc gtcaccggtg ccgcttccgg tctaggggcg tacatcgcgg aggcgctctc
    39061 cgcgaaaggc gcattcgtgg tcctggccga caaagacatc attggcgctc gatcggtcgc
    39121 cgacaggatc cgctcatcgg tccctggagc cgaaccgacc gttcacgagc tggacctggc
    39181 cgacctggac tcgatcgaac ggttcgcctc ctggtaccag gccgaacaca atacgctcga
    39241 tattctgatc aacaacgcgg gaatcatgac cccgccgtac ggacgaacgg cgcaagggtt
    39301 cgagtcgcag atcggggtca accatctggg gcatttcgcc ctgacctatc atctgttccc
    39361 ccttctatcg gcgaccaccg gttcccgcct ggtgacccag accagcatcg tgcaccgcgg
    39421 agggaagatc aacttccagg acattaactc ggagaggtcg tacagtccct ggaacgctta
    39481 taaacagagc aagctggcca ccctgctgtt ctcccgagag ctggacagaa ggctatccta
    39541 tataggcgtc gatgcgccga tgagcatcgc ctgccacccc gggctggtga acacccagtt
    39601 atatcggaac cgggagagga tgcgcagttg gctgaggccg ttcatgcacg atctggaagc
    39661 tggtgccatg ccggccctgc gcgcggcgct cgatcccgcg gccaaaggag gtcagatcta
    39721 tggcgcgggc ggttggatgg agttcaaagg cccggccgtt ctggtcccgc cgcatcgccg
    39781 agggaaggac atggaactgg catccagggt ctgggacctg tctgagaaga tgaccgggct
    39841 ggacctctcg gcgcgcatca aggagcgcag gccatcggct agcaggtgaa aaaaggtctt
    39901 tatcaggaac attgttgccg gtacatggac caactgaccg tcgtcgggtt gcttgccggc
    39961 ctgataacga ccctgggttt cgttccccag gtggtcaagg gataccgcag cgggcgcatg
    40021 gaggacgttt cgctcatcat gcctgcggtg ctcatggtgg gtatgggcct ttggctggtc
    40081 tacgggatct tcctcaacga tcttccgatc atcctgtgga acgcggtctc catagccctg
    40141 aacgcggtca tgatattcct gaagctacgc tccgaccgag gaaagaagaa aggggcggac
    40201 ccccagttca ctcgctgacc ctggagaacg ggcagaccga gatgcatctt ccgcaggcca
    40261 tctccggctt gctcccgtcg ccgatcagct tggcctcgta gacaccgcac ttggcccagt
    40321 cgatgaccag gtcccggctc tccgggtgat gcttgaagtt cggtcccttc agcaccttca
    40381 tggcgcagcg gtcgacgcaa gccgtgcagt cgccgcactg gttgtcgatg agcttggctt
    40441 ggcgggtgac tggcatgttc gtgagcaccg cgcccatgcg ctgcctggcg ccatactcct
    40501 cggttatcaa gagcccgttc ttgcctatcc atcccatgcc cgacagggag gcgatggcct
    40561 tctgggatat cggtccgagg agcttttcct tatcgaccct cagcgcgggg tcgacgaacc
    40621 tggcctggta accttccgcg gcaagtattt ggacgatctt ctcgcccgcc tccttgagct
    40681 tcttgttgca catcttgtag gccgagcgca tctcctcgct gggcttcttc aaggacgcca
    40741 gggcggcttc cttggggatc tccacggcga aggtcaccgc ataagggaac tcgaaggtcg
    40801 tggcatcgcc agcaagcatt cctttcaatg gagacaggtc cgcgaatcct accaggccgg
    40861 aaccggactc ccgggcggca gcttcgatct tctgataaat ggtatctgaa tggtcagagg
    40921 tcatgggccg tcgatgggca tggcccaatc ataaaggtta tcacagaaag aacatacggt
    40981 cagatggacc tgccatccaa gtacgaacgg ccctgctccg tcagactgta tacgcgccag
    41041 ttcttgttct ggcgccatac ggtcagtttg gccttctcca ggatgctgag atgataggac
    41101 agcttggagt ccgtgagccc cgtaagttcc ttcagaacgc aggggcagag ctcgctaacg
    41161 cccaacagat ggacgatctg caatctcacg ggatcggaga gcgcctggtg gcggtccgcc
    41221 tggtccttta tggagtcctt gtccgggacc tttgacagga gcccctcgcg tcctccagca
    41281 tcccgaagcc cgtcagccac ttccttgggc agggaacagt taccttcgcc agacccgccg
    41341 accccttcgt tcgccatctt accagctcac cgaacaccac agaggcgcac ctcgttattt
    41401 taccttcggt tacttgcgga attaagccac gaccgttcag aagatgtcga gcacctggac
    41461 gtaacggtac agaagataga tcaccagggc gtaaccggcc acccggatcc cgaagacgac
    41521 cagttccagg ccatcgaaca gtcctacaag tatcatgagg tgggataccg cgaacaaggc
    41581 gaagaccccg gccagcatca acggcaaggt gtgcttactc ctacgatatc ccagcagtcc
    41641 caaccccacg atggtcaggc acagaaggag gttcgccagg gtcagcaggt ctatgtccat
    41701 gacgtcctgt actattattt cagatgctat attaaggaac cagtcatggt ttcgttctga
    41761 gcgattgaca ttccggacac agtatggtgg tccggccgcc gatccggatg gctgcgagct
    41821 cagtggaaca gcgcgggcat gccgcaccct cccttcggtc ccgaagcagg aagccctcgg
    41881 gaagcctgga gaactccgtg cgcaccgata tggaggcttc cagaactttt ctgacgcgct
    41941 tcccgagcct agccatattc gcctcaggta ttgtgtcggc cttggtggca ggatgcagat
    42001 gctcttggaa cagcgtctcg tcagcgtaca ggttccctac gccggcgatc agcgactggt
    42061 ccaaaagcag cggtttgatg gaaccccgtc ggccagccat ctgcgagacg aagaccttgt
    42121 ccgacatggt caaggcgtcc ggcccaaggt ccctttcggt cagcaggtcc tcgagccgat
    42181 ggtagaggcc gaaccggccg aagcgccggg ggtcgtcaag gaccaaggca ccctcgtcca
    42241 ggcccaggcg cagcctttca tgaggagtgg tctcgcgatc atccaccaga tgcagtgagc
    42301 cgctcatgcc aaggtgtatg aagagatggt cgtccccgat cctcaccagc aggttcttgc
    42361 cgtggcggtg ggcgtcaccg acgctccgtc cgatgaaagc ctcccgcatg gtacgctcgg
    42421 acccgttggt cagcatcttg tggtccttga cctgcaatga agcgacccgc ttcccattca
    42481 ggcggtcctg aaccaacatc ctggccatct ccacctccgg cagttcgggc ataatgacac
    42541 gaacgaccgc atcgtacata atgtgctcga atggtcacat gtgtccgctc ctgtttagta
    42601 aagtgctcaa cctagcctag ctcaaggaat aatggagggt gatgcttcaa tgagcgacaa
    42661 cgaatgggcc tgcggcgatc gcagggattg gaggtcggtc aagggaatga gctggcgtgt
    42721 cacggtcagc gccgtatccg cgttaggatg gttcggtttc gtgatcgcct ggcttttctt
    42781 cctggccgat ggatacagca tactgcagaa ccttgcggtc ctcatgctgt ccgtggtggc
    42841 cctggccatc atcaacgtga ccgcctggat gaccttcgcc cagagcatgg gcgagctgaa
    42901 ggacatcagc tgcgaagggg agaagcacgg catggccaag ggcgccctcg cgctcatctg
    42961 gctggtggcg ataggggtct ggctgttctg gtacgccggc gattacagcc tctaccagaa
    43021 cctggcggtg ctgctgctct ccatcgtccc ggtggcgggc atcggcatgc tgctgggaaa
    43081 gtgagctacc acatcaataa cgaagggggt tccgaggccg ctttttccag gacctccttc
    43141 aacttttctt tgctcggcac tccgccgaac aacgtcaatt tctcattgac aaagagggcg
    43201 ggagcgaccg ccgggccgta cttgccatac agcggctgga tcgcccccac gaagaagtag
    43261 gtcaggctca tgcgggcctc ggtggccgtg accaggtcga ggtctgcttc cacaccggtc
    43321 tcctccagta cctgccttat cagttccagg tatcttttat cgtgcaccgc ggtctggggg
    43381 tggcagcagg agaccgagaa gacggtcagt ttgagcctat ttcccataca gctccctccc
    43441 caccttccta agcatctcca tcccgtacac gtccgtatcg aacagcggga cctctatgct
    43501 tgggatggcg gagaagcgtt gggcgatctc cttgagatat ttgtcctggg tggccctcct
    43561 ccgctccagg aaccagttgc cttgcagaac ctcccggggg atgacctcgt tgatgatcaa
    43621 agatttcacc ttgatgccga aaccgcccag gtcctctatg gccctggcgg tctcctctat
    43681 gggaagtttc tccggtagca gtactaagtt gaaggcggaa acggtctcgt cagataggcc
    43741 gcgcacggac ttgtcgtagc gcgctttttc cgcctccagg tcggctacca tgttctcgtc
    43801 gtagacgaaa cctagaactt ccgaaagctc gcggcggttc ttgatctggt tggatatata
    43861 gccggaccaa tcgaagggca tggacagctc gcgcaaggtg tgtccggtcg gcgcggtatc
    43921 gaagaccacc ttgtcgtgct cggtgtcctc gaagtagctc acgaactggt cgaaggcggc
    43981 gatctcctcc gtgcagggag tagatagcag ttccgaaccg aacatggacg agaacccttc
    44041 catcatccct tccagcctag tctggaacac gcccatggcc ttcttggggt tgatgttgag
    44101 gccgcacagg ttgcgctcgg tcccgatctt ggtgatgtcg gtggcgctga tctcctggcc
    44161 gtagatggct gataggctta ctgtgggatc agtggccacg atgagcgtct tgtaaccgtg
    44221 gtcggacaac cacgtcgcgg tggtggcggc catggtggtc ttccctactc cgcccttgcc
    44281 tccgaagaac aggaacttgc gcttctctat tatctctctc atgctctcct gcgtcatttc
    44341 gatcgtcttg agataggggt gagcctagat attgttatgc tcgccttcat cattttttat
    44401 aacacctcgg ccttgttgca aaatcacagt gaccgggcta gcccggtcac tgccagctga
    44461 tgcaggttga acatgatgag cttgcaccga acctcgtttt ccctagcgtc acttttccgg
    44521 catcgaactc gatgaccgaa cagatttccg atcatgctga acaccgtttc agcatgattg
    44581 cgcttcgccg tcagggcggc ga
//
LOCUS       DAOPZI010000009        43364 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_742_length_43364_cov_8.683484, whole genome shotgun sequence.
ACCESSION   DAOPZI010000009 DAOPZI010000000
VERSION     DAOPZI010000009.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 43364)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 43364)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43364
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_742_length_43364_cov_8.683484"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            154..741
                     /gene="trmY"
                     /locus_tag="PKM11_03100"
     CDS             154..741
                     /gene="trmY"
                     /locus_tag="PKM11_03100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (pseudouridine(54)-N(1))-methyltransferase
                     TrmY"
                     /protein_id="HNX47527.1"
                     /translation="MRRFIVIGHKAATAADFKLDDLAGGAGRLDVLLRCINSAFFLSH
                     DLRKDVEVVLVLQGPPGPARSIRLVGSELRYLNPDERSTGALIRNALMRDAQTEERST
                     PGIYVSTRTYQDVLGLLGDGTEIVYLKEDGTDIRDTELSENVTFVLSDHMDLTPDEEG
                     LLLQYRPKVVKLGPVSYHADHCITIVNNELDRRSL"
     gene            779..973
                     /locus_tag="PKM11_03105"
     CDS             779..973
                     /locus_tag="PKM11_03105"
                     /inference="COORDINATES: protein motif:HMM:NF021415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2116 family Zn-ribbon domain-containing
                     protein"
                     /protein_id="HNX47528.1"
                     /translation="MNQKIAQHRHCRSCGKAFVGDDKYCSEECEEGKELTLRKKKRQL
                     LTLYVISVIIMIGALVISVL"
     gene            973..1932
                     /gene="yjjX"
                     /locus_tag="PKM11_03110"
     CDS             973..1932
                     /gene="yjjX"
                     /locus_tag="PKM11_03110"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0046128 - purine ribonucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HNX47529.1"
                     /translation="MKVGVGGTFNVLHKGHRRLLETAISNGDVLAVGLMSDDYCRRHK
                     VVVLPYAERERALREFLETKGVEFTVHPLNAKEGTAPSDPELDVLIVSQETQTLGPKI
                     NDIRLGLGLRPVRIVVVPYVLADDFRPISSTRVLEGVIDGEGRLLRPLVVNVGSDNPV
                     KIAAVREVLRRLHPELTVNAVAVSRTVGEQPWGTEAERGAEARARECLGTGDLGIGIE
                     AGVLEKSDGLYDVQHCVIVDGTGWTTSGHGMGFRYPPAVADLVRKGMTVGDACAQLFE
                     EGDQGSGKGAIGILTNGILDRKALTEQAVLAALVPRIRKDLYV"
     gene            complement(1929..2165)
                     /locus_tag="PKM11_03115"
     CDS             complement(1929..2165)
                     /locus_tag="PKM11_03115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47530.1"
                     /translation="MSVCPRLGPDGRCNGLYYGFACIKDKCQMEDRDASCLHCIGGDY
                     CLKYGRFGCVGPSNCATKEDYLTSIRKARDRASV"
     gene            2352..3416
                     /locus_tag="PKM11_03120"
     CDS             2352..3416
                     /locus_tag="PKM11_03120"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HNX47531.1"
                     /translation="MANDEELRRAAMIALTECLAVKEGERVLIITNLGGDVYEICQEL
                     FRQASELKAVPVMVIQQDKDTFTMADPAVLDAIRGEPEVIITICRGRVGKDPYGMHIG
                     YVGRDGQKYSHLYEKVLDGDKRTRSFWSPNCTREIFERGVPIDYALLRKNAKALKERI
                     DAGKEVRVTSPAGTDVRFGIDGRQGHYDDGDFTLPGKGGNLPTGEVYVSPSNGTAEGV
                     IVFDGTVDLDTHAERPDVPVRVRFEKGYAVEITGGETARQLEALLERSATMARDQGKR
                     DEERNARHLGELGIGLNPNAKMSCNTLEDEKVGGTVHFAIGMNLENDAHALVHLDCLV
                     LRPDVYVDDVLIIKEGRPIL"
     gene            3496..4716
                     /locus_tag="PKM11_03125"
     CDS             3496..4716
                     /locus_tag="PKM11_03125"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47532.1"
                     /translation="MALGYRGFDRRMWVLFWSMLIDGVGYSLISPYILLFLKHDLGAS
                     MAMGGLVLTIAGVIGAGGNMIGGLLADRYGRRGVMVISMLLRSLTFVLLAIMVTFRPE
                     FVSIAVLLTLSYFFGGVFQPANNAMIADLTEPARRMEAYGLIRVAWNVGFAVGPIVGG
                     MLILVSFPLTFTISAIISFVAAAIVALMLTESYVPVPKGKKEPGLKGVGNLKPLFLLF
                     CLFTLPLFIMSGQFGSTYTVFANDRVGIDTATIGLVFGLNGIMVVLLQMPISRWLTER
                     NPYVGMLAGSVVYSIGFLLVAAVTDGYWLALTMIIITMGEIIVVPVSNALTVLLAPDD
                     SRGKYLGVFGVVSSFGWFGSTFIGGMLYDTYDNGWIMWGILASFGLITALAMIPLWLR
                     TRTKVERTTSQVVR"
     gene            4793..4927
                     /locus_tag="PKM11_03130"
     CDS             4793..4927
                     /locus_tag="PKM11_03130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47533.1"
                     /translation="MSDMKKKKKAESEPSNNNRSDHKGSKPSSAAVGEVTGSKKKGKK
                     "
     gene            complement(5011..5097)
                     /locus_tag="PKM11_03135"
     tRNA            complement(5011..5097)
                     /locus_tag="PKM11_03135"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5059..5061),aa:Ser,seq:tga)
     gene            complement(5102..6757)
                     /gene="pheT"
                     /locus_tag="PKM11_03140"
     CDS             complement(5102..6757)
                     /gene="pheT"
                     /locus_tag="PKM11_03140"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009328 - phenylalanine-tRNA ligase
                     complex [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HNX47534.1"
                     /translation="MPVINFNLEDLKSLIGTKMEDREVLDRIPMIGADFHDFDPVTKE
                     ASIEFFPNRPDLYSVEGLARALRSFFDIELGMRTYDMSASDIVMRVEPSVKNVRPYVV
                     GAVIRGVVLDDKSIRSLMELQEKLHLTVGRKRAKVAIGVHDLDKVHPPFVYKAVSPTS
                     ISFVPLAKEEMMTLAEVLEKHEKGKDYKQLLDGKELYPVILDAKNDVLSFPPIINGRL
                     TTVTTETKNLFIDVTGTDQNTISGVLNIVCTSIAERGGVIETITLRGEEKGMTPNLRP
                     KQWLLDVDKTNAALGLDLEPLAMCQCLTRMGYSAEPKGRKVKVSSSPVRMDLIHQADV
                     VEDVAIGYGYENFGNSKPLSRTIGGERRMEKVADLVRQMMVGYGHWEVTTLTLSSMDE
                     QFSKVPYPEVQAVEVLNPVSEDHNCLRVQLIPSLLTVLRRSKHRDLPQRIFEVGDVVV
                     DAKRRKHMAVMSVHSKASFTEMKSLAEGVLKELGVQCSLVPGDLGMFIPGRCAMIKVN
                     GRTVGHFGELHPQVITAYEIGYPIIAFELDLQDLMSGRGEKIV"
     gene            complement(6820..7974)
                     /gene="hmgA"
                     /locus_tag="PKM11_03145"
     CDS             complement(6820..7974)
                     /gene="hmgA"
                     /locus_tag="PKM11_03145"
                     /EC_number="1.1.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase (NADPH)"
                     /protein_id="HNX47535.1"
                     /translation="MSSHDGLRNKGKTRTDMEDRRKAVESFTGARLEHAGHCSYDPVL
                     AEKNVENMIGTIQVPLGFVGPLKVKGDHADGEFLVPLATTEGALVASVNRGASIISAS
                     GGAEVIIIKDEMTRAPVFRTKGVRDCRRVVEWVNENFEELKAVAEATTKHGKLAKVRA
                     FASGRSLFLRFSYDTGDAMGMNMCTIATEAACRVIEERTSVKLISVSGNMCVDKKPSA
                     MNFIDGRGKTVLADVRIPADLVKDKLHTTPEAMVETCYRKNLVGSSMSLSYGFNAHAA
                     NMLAALYIATGQDAAQVVEGSMASTTCELCEEGVYLSVRLPCIEVGTVGGGTKLPCQS
                     EALKMMDCLGTGKAKKLGEIAAALVLAGELSTLAAQSAGELGKAHKALGR"
     gene            8211..8633
                     /locus_tag="PKM11_03150"
     CDS             8211..8633
                     /locus_tag="PKM11_03150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine decarboxylase"
                     /protein_id="HNX47536.1"
                     /translation="MYTMSPMSGKLLSDEEAMVKYVKDNQWGLATAIDLRHCDPQKIR
                     SKEVITQFAIDLCDYIKMNRFGDPIVVRFGPIPKVEGYSLCQLIETSMISGHFAEDTE
                     RAFLDVFSCREYPPKKTAEFCKKYFGAKEMEYSVSFRN"
     gene            8832..8906
                     /locus_tag="PKM11_03155"
     tRNA            8832..8906
                     /locus_tag="PKM11_03155"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8867..8869,aa:Ile,seq:gat)
     gene            9089..9268
                     /locus_tag="PKM11_03160"
     CDS             9089..9268
                     /locus_tag="PKM11_03160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47537.1"
                     /translation="MANNYANDTNFDLKVPFEIHALESFGILIPENKPELKAAMDIVI
                     NVLIADGTRDEIMIK"
     gene            complement(9450..10937)
                     /locus_tag="PKM11_03165"
     CDS             complement(9450..10937)
                     /locus_tag="PKM11_03165"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47538.1"
                     /translation="MQLVDVIDKYASKEDISIMMRSSGMPSNGSKREMLALIKRQFNK
                     GNAAPILTRLPQTVLVNIVRNERTSAGLLSKMGFASKTELVNIILREIVQEDSPVISK
                     PAYPTPSQQPYPQPMAQQINVAPAQLLNPFLDVPRQKLFDMLMNLDKDSIQSILFKLG
                     LAVSGNKYEIVVRLINSQEGNPQAIIPLIDLANLQYLASQIGMQRKRLKDEQINELLT
                     NYFGLPPIVQQIPATQQQPVDVDPTKTLTDDISRKLFEVLNKVDKDSLKTVLLRQDLP
                     VSGRKEDVVLRIMDANERSPKMILNRLDGYALQNIASAYDIPKRRSKDDQINDLLHIL
                     FGFENFEEKVHPKEEVKPAPVIPLFTGKKEPVKTMTNADFESIISEIELWIPSKSYST
                     EDGYRAELNMFLAGKGHHTRMDTGETLVDILVDHKYPIEVKKSPRGPDYDRAFGQIFR
                     HLDAFHCVIVVVCSPKNMNELDDFRDRIRRTAEGLNHPYKLIIKA"
     gene            11503..12714
                     /locus_tag="PKM11_03170"
     CDS             11503..12714
                     /locus_tag="PKM11_03170"
                     /inference="COORDINATES: protein motif:HMM:NF024241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47539.1"
                     /translation="MVRGISTSRRFLLVLGLVAALAIASSTMSKNPALPLLALHIGAD
                     DAQIGLIAAISPIPGILVSSIAGAYSDRHGRTRLITLSLLIFASAPFLYLFITEVWQL
                     ALVRFYHGFATAMFMPVAMAAVADRFESANRGEALATFSSFSLVGRFSAPFLGGALIY
                     YTDFTSLYVIIGISAAIALLFSIIAPWKENDVTARVKKFEGTTVSALKEVVKERGIVL
                     TSSIEAVQYFAMGAFETFIPVYMHHSMGSTALEIGFVMGIQVVAMLLAKPIMGRVSDK
                     RGRIPFIVVGLLLGAVTITLMPWVSDIVSLSLLSIVFGLTVATVTASTSALVTDIAGK
                     SAHGSSIGVLRSIMDVGHSTGPFVTGMVVGAFSYTAGFGLAGGLLATGALLFSLGMRS
                     RDRPKGMAPSL"
     gene            12769..13329
                     /locus_tag="PKM11_03175"
     CDS             12769..13329
                     /locus_tag="PKM11_03175"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47540.1"
                     /translation="MNEKGGPKMGTERSLKQVPRPDYATNIPGFVIRFAEVDDVGLIL
                     DFIKRLAEYEQLADEVVATVDVLRDSIFVKHQADVIIGELNGRPVAFALFFHNFSTFL
                     GKANLYLEDLFVDESCRGLGLGKIMFSCLAKIAVDRGCDRLDWWCLDWNESSIGFYKS
                     MGAEPMSDWTVYRVDGDRLKRLADLL"
     gene            complement(13355..14488)
                     /locus_tag="PKM11_03180"
     CDS             complement(13355..14488)
                     /locus_tag="PKM11_03180"
                     /inference="COORDINATES: protein motif:HMM:TIGR01800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/2-methylcitrate synthase"
                     /protein_id="HNX47541.1"
                     /translation="MTGNSSKDVIRGLKDVAAAETRISYIDPSGSLYYLGYDIDDLVG
                     HVVYAEVAYLMIHKRFPNKEELDAFNSELISNMRLPEDVVESIRLSPKGAHPMDVLRT
                     EVSNLGEFDPNVLDISPEENLRKAVKLIAQVPTIVASIHRTRQGEEVPEPRPDLSFAE
                     NFLYLFNGRVPDQAEADVMHRIMILHADHGFNASTFAARVTASTNADMYSAVTTAIGT
                     LRGPIHGGASQKVMEMLDDIGLEAEVEEYIYGLLGDGKKIMGFGHRVYRAEDPRTKHL
                     RHIVQNLCNQKRTMELYNKCSRIEGIVHQRKNIYPNVDFYAAVAMDALGIPKDYYTPF
                     FAASRIVGWVAHIIEQYEDAVLLRPLSNYVGEFGRPFVPIDKR"
     gene            complement(14601..15053)
                     /locus_tag="PKM11_03185"
     CDS             complement(14601..15053)
                     /locus_tag="PKM11_03185"
                     /inference="COORDINATES: protein motif:HMM:NF018184.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HNX47542.1"
                     /translation="MTSIKVVNTKETLAIAVREKVKVSEIPAAIGRMFGELYPHLGKG
                     VHCVGPPFTLYHSWEGEVTDMEVGFPIVGKGVESGNVKTITLPAVRAAVAMHIGPYDK
                     LTDTYHEVEEWMKVNGHMPASFCWEEYLNDPQEVPPDKLKTRLYWPII"
     gene            complement(15126..15509)
                     /locus_tag="PKM11_03190"
     CDS             complement(15126..15509)
                     /locus_tag="PKM11_03190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47543.1"
                     /translation="MKKEKVETPVTEEQASKIAALKVLQEMYSNQLNAFERQIDEVSS
                     LGRVNRNTLYNPAVLHEIEAMAHHKKFEELLSTVWVAQSMLDDIIALQRTVCVLKRSM
                     ADEDIEAAEKKERDIDHGALPYEAM"
     gene            15636..16793
                     /locus_tag="PKM11_03195"
     CDS             15636..16793
                     /locus_tag="PKM11_03195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HNX47544.1"
                     /translation="MARDFSQRSSSIVQSEIRNMTLECTRLGGINLAQGVCDTDTPSE
                     VIEGAHRAALDGVNAYTRYDGLPVLRNAIAKKFKDFNRLDIDPEGEVVCSAGATGAFY
                     CACMALLNEGDEVIVLEPYYGYHVNTLLAMGAVPKFVSMHPPEWELDLEKVKDVIGPK
                     TKAIVVNTPSNPSGKVFDRSELKGLVDLAVDHDLFIFSDEIYEYFVYDDRQHVSPLSF
                     QEARDRVVVISGYSKTFSITGWRIGYAVCDKRWARMIGYMNDLVYVCAPAPLQVGVAK
                     GIEELSGEFYRRLCQQYQGKRERMVRGLQEGGLYPYVPQGSYYILADVSSVPGDDSKQ
                     KAMHILKECGVASVPGSAFYQQGGEDLVRFCFAKTDDVLRTATDRLSRLRW"
     gene            complement(16776..17648)
                     /locus_tag="PKM11_03200"
     CDS             complement(16776..17648)
                     /locus_tag="PKM11_03200"
                     /inference="COORDINATES: protein motif:HMM:TIGR01297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HNX47545.1"
                     /translation="MKKQQVAKLAVGIGLLIFFIKLAAYLISGSVALLSDALESIVNI
                     VASIMMLASIRVAMMPADADHRYGHQRAENISCLVEGILIVIAAVLILLASAGRLLDP
                     QPFTSIGLALMVSLVATALNGGMSFLLLRSSKQNGSIALEGDAKHLLSDVISSVGIVI
                     GLFLAEMTGWYVLDPIMALIVAILLLRMAYSVLAKTCRDLMDHSCPESEAIIESVLNE
                     HGGFLQYHDLKTRRVGYNVYAEMHVCVPAQTTMAEAHDLTESLEKALLQKIPGIVVSI
                     HMETEKECLLPSQP"
     gene            complement(17711..17977)
                     /locus_tag="PKM11_03205"
     CDS             complement(17711..17977)
                     /locus_tag="PKM11_03205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47546.1"
                     /translation="MDDRIRRLYQANRKSIMKLSRTKNKGGKAATQVDVMLETGEVLL
                     SVNIRPSRVIYTEDQSFLTFFVKHDPKLSESEVDALFEKALAEK"
     gene            18124..18411
                     /locus_tag="PKM11_03210"
     CDS             18124..18411
                     /locus_tag="PKM11_03210"
                     /inference="COORDINATES: protein motif:HMM:NF017088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HNX47547.1"
                     /translation="MVSMKDIISKSVLTLDAYNVGAVNDFQVSVDDWGVKMIGVTLNA
                     QSKKDLGIKKLALTGLTLCIPIEHVDKVGDMVTLRIDFDHLKDLPECKNLL"
     gene            18475..19635
                     /locus_tag="PKM11_03215"
     CDS             18475..19635
                     /locus_tag="PKM11_03215"
                     /inference="COORDINATES: protein motif:HMM:NF024423.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HNX47548.1"
                     /translation="MSQGPMNARLIYKFFEAANMQRWNDHIRPVELTELDKQSHKMVI
                     AYVLARFEETEKGTKIDWTRIIEGGIFEFLHRIFLTDLKPPVYHRMQKEKGGELNEYV
                     FRELLSEVPDIDQDFFERFKAYHLHKDESVERRVLRAAHYLATNWEFKLVYNANPTML
                     GIEDTKRSIEMQIEDHYDLIGVQRIMLAKKSYGFIEFCGQLRYQQRWARAPRIPRTSV
                     LGHMLMVAIMSYLCSLRIGAPAQRTVNNFYTSLFHDLPEVLTKDIITPVKKSVGGLEE
                     LISNYEEQQVEEKLLPLLPATWRKDFEQLLIDPFRNRNREDGSWAVDGAMLKGCDNLA
                     AFIEANSSIKYGVSSKVLRIGKQRLLEIYQDNGNIAGIDFYQLMQELDHMDI"
     gene            complement(19636..20166)
                     /locus_tag="PKM11_03220"
     CDS             complement(19636..20166)
                     /locus_tag="PKM11_03220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47549.1"
                     /translation="MMPTCAKCGKPLLEDMRFCPYCGQPMVAEEMERFEPAKGEIVTS
                     VAAPAYIVGRQGVFAMAMTSGKLIFARIQEVQLDRGKAELRQAGIFMPGSSSSDNVSR
                     FYEMSPEEVLVETKDNFSVEASDVTSVRLSYDGDDEGKYVINIRAEELELTFTLPYDK
                     YYRDLLFRLFDGRVTW"
     gene            20345..20704
                     /locus_tag="PKM11_03225"
     CDS             20345..20704
                     /locus_tag="PKM11_03225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HNX47550.1"
                     /translation="MEGERITLRLEGEDLELIDDFIEGHPEISNRSQLARIALRAFIE
                     RDGGARVSGSGKGEFVLNVPPAVRSIMEGMVEDGYYNSVEDVVVECLRKEFISRDNLE
                     KVKDEQFQKSRQIMARM"
     gene            20807..21619
                     /locus_tag="PKM11_03230"
     CDS             20807..21619
                     /locus_tag="PKM11_03230"
                     /inference="COORDINATES: protein motif:HMM:NF012320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47551.1"
                     /translation="MEAGIMEQTVRTEQIVSMLSRGLAEPRISVVGCGGAGNNIVNNI
                     FGSCKKNVQTVAINTDERSLQKVNAHKKLLIGKDVTEGRGAEGFPEVAEYCAECAKDA
                     IKDAIKDRDIVFVIAGMGGGTGTGTAPVVAQMAKDLNSITFVIAISPFSFETERVSKA
                     QMGISKIKQIAKTTVVVENDRLLNVVDEMPLSKAFSVIDNSVVKIIDSFCSQVSLSFM
                     NAFTEEVVQYMRADEKSEVVREQYMMPELVMASKGPAESGLRPMGQLGPIMQ"
     gene            21721..22824
                     /locus_tag="PKM11_03235"
     CDS             21721..22824
                     /locus_tag="PKM11_03235"
                     /inference="COORDINATES: protein motif:HMM:NF013663.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-NAD kinase family protein"
                     /protein_id="HNX47552.1"
                     /translation="MSRSRSVLLGLVINPIAGMGGSVALKGTDGDAYRMAMIKGAVPL
                     ARGRVVRALRRLDGDIGFLTASGEMGAWALNELGLAHEVVWETSGESVPEDTRQTCRR
                     FLDRKVDLIIFCGGDGTARDVLDAVGDKVPIIGIPSGVKMHSAVFANTPEEAGDVVQR
                     FVNGETDTRLSEVMDVDEDAFRHGELRARLYGYVKVPDLSGLQPPKGALFGTSDEEQK
                     EAIAEFVVERMEPGTIYVLGPGTTTKAVADRMGQPKTLLGVDVYLDGKAILTDASEED
                     LLRILIGRPARLLVTPIGRQGFVFGRGNQQLSPRIVDMVGLENLLVLATPTKLADTPV
                     LHSDSGDIELDRRLCGYRKVLIGYDQYRMVRCR"
     gene            22864..23301
                     /locus_tag="PKM11_03240"
     CDS             22864..23301
                     /locus_tag="PKM11_03240"
                     /inference="COORDINATES: protein motif:HMM:NF013994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding domain-containing protein"
                     /protein_id="HNX47553.1"
                     /translation="MSVIHLDFRTFGQATEVEERVRKAMTFSSGIEDIKVEHSEGYHG
                     NKILIMTCTVSRKADIRSFFRRLSRDDLSLLLDSIDQRMDEDGQFFFRLDKQKAFQEE
                     LVISSGDDCIHVRAKVESYPKRREKALENAKVMLQELLDRQAK"
     gene            23326..23412
                     /locus_tag="PKM11_03245"
     tRNA            23326..23412
                     /locus_tag="PKM11_03245"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23362..23364,aa:Leu,seq:tag)
     gene            complement(23419..23901)
                     /locus_tag="PKM11_03250"
     CDS             complement(23419..23901)
                     /locus_tag="PKM11_03250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47554.1"
                     /translation="MAKPRFVDHPLNADIDRLARSSDHRTLAIWAANCAERVLPLFEK
                     EFPADERPRLAIIKLREWARTGEFHMTEVRRASLNAHAAARSMPPGSAAQFAARACGQ
                     AMATSHVPTHSIAAAWYAAKAVWASDPTNHTLIAIEREIQYQLLLGRDDVKMRRSDDK
                     "
     gene            complement(24212..24949)
                     /locus_tag="PKM11_03255"
     CDS             complement(24212..24949)
                     /locus_tag="PKM11_03255"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47555.1"
                     /translation="MRMDAQEGGWAGVSGNVRGRCQGCPRDPQKVPVLFEPKDPGKVD
                     FIIVSQEPGHWLRPLGDGVPSKLISLTLGKGSLDEVRKANPLSKVAQIFGPFDPSASR
                     VYWTHALKCVPVNGDRDVNKEWRKAATRCKEHFMSELKVLGKNELNILAFGKYALEMC
                     LNVLDDQDIDQELSISEFMQSVKLPLVYKHRFKDGTVKNVNLYVFTNPSAEVVKIMKS
                     GGKMTADEIQELEIKKLQETLGKRNAR"
     gene            25072..25491
                     /locus_tag="PKM11_03260"
     CDS             25072..25491
                     /locus_tag="PKM11_03260"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX47556.1"
                     /translation="MMERHIARKKVKEIMTSEVVTITPETDLRTLKEMFERYDYNSFP
                     VLEKGKMVGIVSKLDLLKAFSPGLNVSVSRALKLFSKDAAGIMHTATVFVSPEDDVSK
                     AADYMVEFKLRSVPVLEKGVLKGMVSRQDIIRCLKVE"
     gene            complement(25466..26104)
                     /locus_tag="PKM11_03265"
     CDS             complement(25466..26104)
                     /locus_tag="PKM11_03265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HNX47557.1"
                     /translation="MIIETLNQIIIDLIEATGYLGIFLAMLIEGIFTPIPSELIMPFA
                     GYVASTGELNYFLVILIGSIGAVVGSTVAYMLALWLGRPLIDRFGVFFGLDGEKMASA
                     ERWFKRWGVWGILIGHSLPGIRSVISFPAGLSKMDRKKFVAFTFSGALVWNTVLVTAG
                     YLLGGEWVKFWEKTDSLHLDILMLGGLGAILVLYFLYNRRKGSKLTRPSDSE"
     gene            26235..26669
                     /locus_tag="PKM11_03270"
     CDS             26235..26669
                     /locus_tag="PKM11_03270"
                     /inference="COORDINATES: protein motif:HMM:NF039321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47558.1"
                     /translation="MSDTNLLSSLGHASVVRVLEKTAGFNGPVADEVALRVLNYFGYL
                     DEIIDNALDHDDRRLFYFLQDMKILRTRWEETQLASGRNWRIFYWSFNWESISQILED
                     KPPTNETVDIYRSLPDSAWCREKQEGTARGKTIIPSNRMTVT"
     gene            26666..26980
                     /locus_tag="PKM11_03275"
     CDS             26666..26980
                     /locus_tag="PKM11_03275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47559.1"
                     /translation="MKFCYCPDCKDLQPTAWYRRKSCKLCGGDCRIISVPMYYYGVAM
                     YALSAVGAFLVGAEILRYDLGLGDLRLYLMFGSLIVAMIFASLETARAVEIAQKKVGK
                     VL"
     gene            complement(26977..27441)
                     /locus_tag="PKM11_03280"
     CDS             complement(26977..27441)
                     /locus_tag="PKM11_03280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47560.1"
                     /translation="MALRKDRRGMAVLVDALIFLVVLTLLIAVIYSASPGKMSEDRTE
                     RLRSYHSVMLAGEVSANEGSSMSVVTLAEYLIALSIIGAPEEEQVLLIEKMVNGTITE
                     LEMTFGNTWLVIDLGSAVLHFGSDPSAEVGDVYADRRELGDGSVVSTMFLTV"
     gene            complement(27432..27839)
                     /locus_tag="PKM11_03285"
     CDS             complement(27432..27839)
                     /locus_tag="PKM11_03285"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47561.1"
                     /translation="MDREGVGGFLESILAVMVVITASSIFLVVLASGTVQVEEEIDQE
                     EVMSWLISNDLYFEDEVVSLDGPGVGPRLTGLPEGISGMTIVYRASGNSTPLFVLNQA
                     EQSTGDVLAFQRPLLIELNGTKFPGVMEVRVWR"
     gene            complement(27914..29839)
                     /locus_tag="PKM11_03290"
     CDS             complement(27914..29839)
                     /locus_tag="PKM11_03290"
                     /inference="COORDINATES: protein motif:HMM:NF013316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HNX47562.1"
                     /translation="MELLAPVGTEEALKAAIAGGADAVYLGGKSFGARHFASNFSDEL
                     LAGAIKLTHDRGMRTYVTVNTLIKEGEMADALSFVGMLDDAGADAVIVQDRGLLPLIK
                     ERFSIPVHASTQMAVHTSAGVSWAQKQGIERVILARELGLEQVKEIAESSNIGIEVFI
                     HGALCYCFSGQCLFSSFLGGRSGNRGMCAQPCRKSYTLGKKEGYLLSTADTFGIGSIP
                     ELMRCGVTSLKIEGRMRSPQYVYLTSKIYKKAIERAKNGETPLITDREREMLEVVFNR
                     GFSGGYLTDQEVMQTAHPESRGRPLGPAQVEKGRLRMPRGALGAGDGISLYQGNEKVG
                     GFDLKGSDLDGTNVIASPPFLLKDGDYTVYKTKDRELPVIEDLISKIGLQEREAVRKT
                     VELPPKRRRRGETVSELSFYVSSLAVLRSVLPYADRVYFDGAKVDAEAEEICASEGKE
                     FVKMLPRLSLKESASDHDRVMVNTIDQYELNKGRTVYGSYHMNFFNSYTLPKLHQCTL
                     SPELNQEELIHVLSRTEGRCEVMAFGRLELMLSRDPTLPEGTLVDDRGVRYPVHRDPE
                     GFVHILHSTDLLMLDKVPELRTMGVDSLGIDVRRRHPDLAAFVGKSFKELDMANLEEL
                     RRKCGRSSLGHYRKGVF"
     gene            29942..30487
                     /locus_tag="PKM11_03295"
     CDS             29942..30487
                     /locus_tag="PKM11_03295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47563.1"
                     /translation="MAKVVMMPKRGDARPAMRPNQEGCKFQLLGRMIELDCSVCPHAD
                     EAPSERCLGAIRDSLNAHREATGIVMSGAQDVWVRESGVNSLRTLIAAETAWKGLRDI
                     LASLPCPRPISPERINRYLDRIRAGSSDMFCSGEGATCPSCLERQREALDALRSDGRR
                     AKKTLAADRFRIIEVPGGSDR"
     gene            30484..32091
                     /locus_tag="PKM11_03300"
     CDS             30484..32091
                     /locus_tag="PKM11_03300"
                     /inference="COORDINATES: protein motif:HMM:NF012652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system ATPase subunit"
                     /protein_id="HNX47564.1"
                     /translation="MTKGPMELSDALPGLRRSRMVKPSLSGYWIEREAPAGWQLVDRK
                     EIPGGTIEIVADPMGVRQRYCVLPWEHTADRDSSRLLAKAVAKVRSVPPASLGGEESE
                     LRSHVRSLVRSLNPPAGIENELLDAVMRNTLGLGVLDIILRDPRVEDIYVDAPCQDTR
                     AYLTLNQAGGRNIFGRCETNVIVSEKEMVGLVGRLKYRSGRPFSRSSPVLETDIADAG
                     VRATALCPPLSPDGLALALRRRSDVPWTLLRLAERGSLDEVAAGLLSFLMDGRASILV
                     CGARGSGKSSLLSALLFEFPVDQRILVIEDTREVPVKALQSLGFKVQSMLVDPSLSGD
                     RTSSAEEALRVSLRLGESAIVVGEVRGREAMTLYESMRTGKAGSSVLGTIHGDGAKEV
                     HDRVVNELGIPEASFASTDVIVTMGLVRPGGGLGQVRRITEVAEVVRTPEGLSFLPML
                     TYDGRYHLSERHMPILARIAAGWGMDYQQGLENLRRRIALRGSLLEMGREDPAYLSPA
                     YSLQANEYLWQGGKETGQEFIDHLRGR"
     gene            32097..33791
                     /locus_tag="PKM11_03305"
     CDS             32097..33791
                     /locus_tag="PKM11_03305"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47565.1"
                     /translation="MLGTTGLPKIAGTVPAGFAKIFSPKLRPGMQESMSRREESVEDV
                     SLAAYNAFLWSLLVFVPAIVIVLLFMPYPLVMMAAGLVVAPFLLPALIIAGPSSRYAA
                     EQRSFLIDTPAVIGAMGMSMSRSPSLERAVEMGTRSGDGGLQKAIASVAWKALTGEAA
                     DLRRGLSAWTSGLDKMNDGLRRALHLIMAAEESEGEGRERLLDRANSIALEGLKEVCE
                     RYIGSLSFPVMLVFAFGVLAPVMLFSLIPLLGMENGLVGGDLNLGMLGLVLLLLVPAF
                     TLGYIRSMMARNPLRGPRRKLDLDKSRLAIVLSSVPAAFLAYVIAGSILVSALAGLGV
                     LLAALIGLGAPEKKGEQDTERSFVDALYRLGNAMLGGQDLERAFEEVAMTDHGEFRLW
                     GLRLVHATRTDRVSLAEAIRADRELASRYPALHQNYLTVMACAEEDHLGAGKLAVNLA
                     QSQGDVARAQAKVRENLRPVVDMMSTTSTLFAPAIIGLTGGIMGLIGGGTVALTALAS
                     IYVVELAFIVNHFLGGLDGWSSRQRGMRSYGTRGAIALGVYLTASLCGQTLLFHLL"
     gene            complement(33745..34179)
                     /locus_tag="PKM11_03310"
     CDS             complement(33745..34179)
                     /locus_tag="PKM11_03310"
                     /inference="COORDINATES: protein motif:HMM:NF014693.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylmethanofuran dehydrogenase subunit E
                     family protein"
                     /protein_id="HNX47566.1"
                     /translation="MAELPDDLRRLADFHGHLGAYVLLGYRMGLVARKYFPGKFYATL
                     FTGTEPPISCLIDGVQFSSRCTLGKGNLAVKEGGRPNARFYDGIRSLEMSPLDAVQRR
                     IDTVNSYEAGEKLSLELHQLSDLELLLVREGGREASDRIVKL"
     gene            34262..34798
                     /locus_tag="PKM11_03315"
     CDS             34262..34798
                     /locus_tag="PKM11_03315"
                     /inference="COORDINATES: protein motif:HMM:NF021384.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2085 domain-containing protein"
                     /protein_id="HNX47567.1"
                     /translation="MKVPVAKRYMLIIGAVLSAILLAMIIAPLTIPEGTVGGLDGSIG
                     SLDHEDDLEFVPWPQRAVYLLGDINCHQQADRSFELNDNQMPFCARDLGLLAGAIVGL
                     AAFVLLGRKVEWAWLLVLLVPMAVDGVVQAVTDYESSNALRSITGLLAGIAAGYGAGM
                     LIKNFFQGPEVENGPSQQ"
     gene            34910..35560
                     /gene="psmB"
                     /locus_tag="PKM11_03320"
     CDS             34910..35560
                     /gene="psmB"
                     /locus_tag="PKM11_03320"
                     /EC_number="3.4.25.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000502 - proteasome complex [Evidence
                     IEA];
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0010498 - proteasomal protein catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="archaeal proteasome endopeptidase complex
                     subunit beta"
                     /protein_id="HNX47568.1"
                     /translation="MDNMKTGTTTIGIVNADGVVLATEHRATMGNFIAHKETQKVFKI
                     DDNVGLTTAGLVGDAQVMARYLRAEVELYKLKRTAPMSVKAAATLTSNILRRGGGAYG
                     YYYVGLIVGGYDKEGGHVYSLDAAGGSIPDHYISVGSGSPYAYGVLEDHYKRDITLDD
                     SINLAIRALNAAMKRDSASGDGMDIVTITKDGYIEVSQEEILKRASRMGINVPRPY"
     gene            35610..37526
                     /locus_tag="PKM11_03325"
     CDS             35610..37526
                     /locus_tag="PKM11_03325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-CASP ribonuclease aCPSF1"
                     /protein_id="HNX47569.1"
                     /translation="MSAETILEDAREQVRKIVPSTVDITSIDFEGPLVVIYTKDMEAF
                     ASGNDMVRQIAQGLRRRVDVRPDPKTLKDSADVEKRLREIIPEEAQIQNIYFEDDTGE
                     VYIEALAPGIAIGKQGAVLNEIKKEIGWAPKVIRAPPIQSKTVYETRAYLREIHDDRK
                     DFLRKVGRRLAQPKTEGDNWIRMTCLGGYLEVGRSATLLHTRDSKILIDCGMWPSKAE
                     PQPKPYFNAPEFLPFDQLDAVVITHAHLDHCGLLPTLFKYGYDGPVYCTPPTRDLMSM
                     SLIDAIKVAYGEAKGNEYEAKHVREVVKHCITLKYGETTDITRDIRLTMQNAGHILGS
                     AVCHFNVGDGAYNVTFTGDMKYERSWLFNATTNKFPRLETLVIESTYGGSNDIQPSRV
                     DAATQLRGIIERAIMERKGKIVIPVFAVGRSQEVMLVIEELARTGKVDKVPVYLDGSI
                     WEATAIHTAYPEYLNSQLRTQIFQMGQNPFLSDMFKRVDSQEMRDNILHDVEPCIVLA
                     TSGMMNGGPVMEYVKAWASDPTASLVFVGYQADGTIGRKIQRGVKELTLPDKGKQITV
                     DFKMNVEVVDGFSGHSDRRQLINYIASLDPKPERIVIGHGEEKKCMDLASALYRKFNI
                     TTRAPMNLETIRFK"
     gene            complement(37588..39117)
                     /locus_tag="PKM11_03330"
     CDS             complement(37588..39117)
                     /locus_tag="PKM11_03330"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: protein motif:HMM:NF014165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HNX47570.1"
                     /translation="MTNDLKEAYSNLMSRSKEMFVLGSAGSILYWDMETKMPPAAQAM
                     RGEQLSALELIVHKKMTDPENDALLKRCESDLSVFDQWQSRNLHLLRKSYDENSKIPD
                     KLVTETAMHQSKCNMVWKKAKAAHDFKMFRDDLAKMIDLREQAAEILMKVKGTKTPYD
                     ALLDQFEPNMTAARIDEVFAELRQGLIKLIGKVESCDYRPDMSPMSRKVPVEVQKKIS
                     LDVMNFIHFDTTSDKAAGRLDETEHPFTTGTFDDVRITTHYYEDRFFSNVFSVMHEGG
                     HALYDQGIPREWMYQPIGTPCSYGIHESQSRFVENIIGRSPEFLNYALPRFRKYSPRS
                     FKGLKNRDIISAANAVVPSKVRIEADEVTYALHVIIRFEIEKMIFSHQVTVDELPQVW
                     NQKYSDYLGVKVEHDGEGVLQDTHWSGGSFGYFPSYALGNIYSGMFLDKMQKDVPQWR
                     KSVRNGDFSPVLGWLRTNVHSKGDLYDPADLVKVVTGKDVSVTPFLKYLDRKMSRIYG
                     F"
     gene            39308..41914
                     /locus_tag="PKM11_03335"
     CDS             39308..41914
                     /locus_tag="PKM11_03335"
                     /inference="COORDINATES: protein motif:HMM:NF013491.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PEP/pyruvate-binding domain-containing protein"
                     /protein_id="HNX47571.1"
                     /translation="MEEVSNTGLPGLDKILERIQLGDNVVLQVDSIDDYVKFVTPFCK
                     EAGRRGRQLIYFRFADHRPVVPEDSKAEVHRLEPIEGFEQFISEILDVIDHKGKGAFY
                     VFDYLSDLSVDWYSDRMLGNFFMLACPYLYVYDTVAYFALIRNHHTPFAIDAIHGTAQ
                     VVIDVHSLGVRTYVHPLKVEGRRSPTMYMLHQWDGDEFVPVLNSSTTAEILTGVPQPW
                     LDYSMHKQDIWTRSFLKAQEFVETNAFERTTDQTCDILFLRLVRMAVTRDPRVMRLIE
                     TYLDISDLLDIGKRMIGTGLIGGKSVGMLLSRAILKKNDQEWAKRLEPHDSFYIGSDV
                     YYTYLSQNGCWWIRRKLNDPASGFLLDDHDKERMLTGKFPEDIVDQFRKMLEYFGQSP
                     IIVRSSSLLEDAYGNAFSGKYESVFLANQGTPQERLDQFLDAVRRVYTSTLNREALTY
                     RAHWGLLERDEQMAVLVQRVSGSVHGDTFFPQVAGVGISYNPYVWSKEIDPRAGMMRL
                     VFGLGTRAVDRVDDDYTRIVAMNAPLRRPEGSSQDVGKYSQRRCDVIDLKANRLTSLP
                     FEDLVRNSPDIPLDIFASRDRELERRVQEYGGNEAFSWILTFDRLLSEGTFLDDVRRM
                     FRVLDGAYDHPVDIEFTANFRDLGDYRINLLQCRPFQAKGDALSLAEPCSIPSARTIL
                     ASEGHVIGSSRAVTVDRMIYVVPETYGKMRMSERYAVARLVGRLTHLKDLGEHPTLLL
                     AGPGRWATTSPEMGVPVSFSEINTVSILCEIISMHEGLVPEASLGTHFFNDLVELDML
                     YCAVYPGRDGHVVSGELFDKAENRLSSLLPDSAGLSHVIKVIDADGLGIRVCSDVRKQ
                     TFTCYQDRKDVP"
     gene            42049..43284
                     /locus_tag="PKM11_03340"
     CDS             42049..43284
                     /locus_tag="PKM11_03340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47572.1"
                     /translation="MSASKRADELRTFLDERIVQRLASSVSRMDARQKVLSLLLITLL
                     IYGPAIAYYLSDPSVQYDFDIYRSRTQTIIDGGCLYRDVHTETPPLINYIMVPAQLLG
                     GAESAYVWGAYEAFFAFLLAVMLYLSFRKFDEMKAFGMGVLTILSPYLIIESATGEDA
                     AIVAFVFFLGAVLMVLDKRYAVLAIALGAWTKMWPVLMMPVEFLRSRGFKKKTEVILL
                     AALITVAITAPFLFLCSDKFLEFISFYFIGDPSRPSGGRSLWNFLRDGGYGLPAIVEL
                     ALVIGSLLIAYLYSHFKNWGAWRSVTLAMLVFIVFYPKMHMGYYVMPFVLLAAWSVSD
                     WKIAARLFLAYIPITYSGGFASDNPDPIFATADGGWIIGLLLVLFALVLICDAARMAF
                     RSPAFLETVQISGGQTELT"
BASE COUNT         9252 a        12174 c        12579 g         9359 t
ORIGIN      
        1 cgcacgcggt tccggaatgg acgccaagca cgttcgtgaa ctgttgcagc agtacaacaa
       61 ttccaagaag gccgtgcgcg gcttcatggg caaccgcaag ctgcgcaagc agctgatgaa
      121 gcagatgcag ggcggcggtc tcgaggggct gcaatgaggc gcttcatagt catcggccac
      181 aaggccgcca cggcagccga tttcaagctg gacgatctgg cgggaggcgc gggacgattg
      241 gatgtgcttc tgaggtgcat caactccgca ttcttcctga gccacgacct gcgcaaggac
      301 gtggaggtcg ttctggttct ccagggaccg ccgggacccg cacgctcgat ccgtctggtc
      361 ggaagcgagc tgcgctacct gaacccggac gagaggagca ccggagcgct catacggaac
      421 gccttgatga gggatgccca gaccgaggag cgcagcacgc ctggaatata cgtcagcacc
      481 aggacctatc aggacgtgct tggtcttctg ggagatggga ccgagatcgt ttacctcaag
      541 gaggacggca cggacatccg ggatacggaa ctgtccgaga acgtgacctt cgtcctaagc
      601 gaccatatgg acctcactcc ggacgaggag ggcctactac tgcagtacag accgaaagtg
      661 gtgaagctcg gtccggtgtc ctatcatgcc gaccactgca tcaccatcgt gaacaacgag
      721 ctggaccgcc ggtcgctatg accgaatctt tatattcctc ttcaaaggtc cgataaccat
      781 gaaccagaag atcgcccagc acagacattg caggtcctgc ggcaaggcct tcgtgggcga
      841 tgacaagtat tgctccgagg aatgcgagga gggcaaggag ctcacgttgc gcaagaagaa
      901 aaggcaactg ctcaccctgt acgtcatcag cgtcatcatc atgataggcg ccctggtgat
      961 atcggtgctc tgatgaaggt cggcgtagga ggtacgttca acgtcctcca taagggacat
     1021 cgcagactgc tggagacggc catctccaac ggtgacgttc tcgccgtcgg cctgatgagc
     1081 gatgattact gccgtcggca taaggtcgtg gtcttgccgt acgcggaaag ggagagggcc
     1141 ttgcgggagt tcctggagac caagggcgtg gagttcaccg tccaccctct gaacgccaag
     1201 gagggcaccg ccccgtccga tcccgagctg gacgttctga tcgtttccca ggagacccag
     1261 accctgggac cgaagatcaa cgatatccga ctggggctcg gcctgcgccc ggtccgcatc
     1321 gtcgtggtcc cctacgttct ggccgatgat ttccggccga taagctccac ccgggtgctg
     1381 gagggagtta ttgacggcga aggtcggcta cttcgaccgc tggtagtgaa cgtaggttcc
     1441 gacaacccgg tgaagatcgc cgccgtgcgc gaggtcctgc gccgtctgca tcccgagctg
     1501 accgtgaacg ccgtcgccgt atccaggacg gtgggggaac agccctgggg aacggaggcg
     1561 gaacgggggg cggaggcgcg ggccagggag tgcctgggga ccggagatct gggcatcggc
     1621 atcgaggccg gggtgctgga gaagagcgac gggctttacg acgtccagca ctgcgtcatc
     1681 gtggacggga cgggctggac cacctcggga cacggaatgg gtttccgata tcctccggcg
     1741 gtggccgatc tggtgcgaaa gggaatgacc gtaggggacg cctgcgccca gctgttcgaa
     1801 gagggcgatc agggatccgg aaagggagcg atcgggatac tgaccaacgg tatactcgat
     1861 agaaaggcgc taacggaaca ggccgtactg gcggccctgg tcccccgcat aagaaaagac
     1921 ctctatgtct agacggacgc ccggtcccta gccttccgaa tggaggtcag gtagtcctcc
     1981 ttggtggcgc agttgctggg accgacgcac ccgaaacgtc catatttcaa acagtagtcg
     2041 ccgccaatgc agtgcaggca ggaggcgtcg cggtcctcca tttggcactt gtccttgatg
     2101 caggcgaagc cgtagtagag cccgttgcat ctgccgtccg gacctagtct agggcagacg
     2161 ctcattccag ccacgcccca gatcgatgat cgcccatcgg gcccccctcc tgctctgaca
     2221 acatcaccat attgattatg ggatgttaaa taatttgcca gaactttttc tttccagctg
     2281 aactggcgat ataataagat cggcccatcg tctcgaaaac ccatatataa tcgccttcag
     2341 ctcaatggcg catggccaac gacgaagagc ttcggagggc ggcaatgatc gcgctgaccg
     2401 aatgcctggc agtgaaggag ggggagcgcg tcctcataat caccaacctg ggtggtgatg
     2461 tctacgagat atgccaggaa ctattcaggc aggcttcgga gctcaaggcc gtcccggtca
     2521 tggtcatcca gcaggacaag gacaccttca ccatggccga cccggcggtg ctcgacgcca
     2581 tcagagggga gccggaggtc atcatcacca tctgccgcgg gcgcgtcggg aaggatccgt
     2641 acggcatgca catcggctac gtcggccggg acggacagaa gtactcccat ctctatgaaa
     2701 aggtcctgga tggggacaag cgcacccgtt ccttctggtc gcccaactgc acccgggaga
     2761 ttttcgagag aggggtgccg atcgattacg ccttgttaag gaagaacgcc aaggccctca
     2821 aggagcggat cgatgccggg aaggaagtac gggtcacctc tccggcgggg accgacgtcc
     2881 gcttcgggat agacggccgc caggggcatt atgatgacgg cgacttcacc ctgcctggaa
     2941 agggcgggaa cctacctacg ggcgaggtct acgtctctcc gtccaatggc accgccgagg
     3001 gcgtcatcgt cttcgacggc acggtcgacc tggataccca cgccgagagg ccggacgttc
     3061 cggtacgggt caggttcgag aagggttatg ccgtggagat caccggaggg gagaccgccc
     3121 ggcaactgga ggcgttgctg gaacgctcag ccacgatggc tagggaccag gggaagcggg
     3181 atgaggagag gaacgcccgt catctgggcg agctgggtat aggtctgaac cctaacgcca
     3241 agatgtcctg caacaccctg gaggatgaga aggtcggggg cacggtgcac ttcgccatcg
     3301 gcatgaacct ggagaacgac gcccatgccc tggttcatct ggactgcctg gtgctacgac
     3361 cggacgtcta tgtggatgat gttctgatca tcaaggaagg aagaccgatt ctctgagctg
     3421 gggtcagtaa cggatatctg aagcatcaag ggacctgaat cagaacgtaa ggcggcaagg
     3481 gaaaggtgga acgacatggc tctgggctac cgaggattcg accgcaggat gtgggtcctg
     3541 ttctggtcga tgctcatcga cggggtaggc tacagcctga tcagccctta catcctgctc
     3601 ttcctgaaac atgacctggg cgcgtcgatg gccatgggcg gcctggtcct caccatcgcc
     3661 ggtgtgatag gcgccggcgg gaacatgatc ggcggacttc tggccgatcg ttacggacgc
     3721 cggggcgtga tggtcatatc gatgctgctg cgcagcctga cgttcgtgct gctggcgatc
     3781 atggtcacct ttcgaccgga gttcgtgtcc atagcggtgc tgctgaccct cagctacttc
     3841 ttcggcgggg tgttccagcc ggcgaacaac gccatgatcg ccgacctgac cgagcctgcc
     3901 cggcgcatgg aggcctatgg gctgataagg gtggcctgga acgtgggctt cgccgtggga
     3961 ccgatagtcg gcggcatgtt gatcctggta tccttcccgc tgaccttcac catatcggcc
     4021 atcatctcgt tcgtggcggc ggccatcgtg gccctgatgt tgaccgaatc atacgtcccg
     4081 gttcccaagg gaaagaaaga gcccgggctg aaaggggtgg gaaacctgaa gccgctgttc
     4141 ctgctcttct gcctgttcac cctgccgctg ttcataatgt ccggccagtt cggttccacc
     4201 tacaccgtct tcgccaatga tcgagtgggc atagacacgg ccaccatagg gctggtgttc
     4261 ggcctgaacg gcatcatggt cgtgctgctg cagatgccca tcagccgatg gctgaccgaa
     4321 cgaaacccgt acgtgggaat gctggccggt tcggtggtat attcgatagg attcctgctg
     4381 gtggccgcgg tcaccgacgg gtattggtta gcgttaacga tgatcatcat caccatgggg
     4441 gagatcatcg tggtcccggt gtcgaacgcc ctgaccgtcc tattggcccc ggacgattcc
     4501 cgtggcaagt accttggggt cttcggagtg gtatcctcct tcggctggtt cggctccacc
     4561 ttcatcggcg ggatgctcta cgacacgtac gacaacggat ggatcatgtg gggcatcctg
     4621 gcctccttcg gattgatcac cgctttggcc atgatacccc tctggctgcg cactagaact
     4681 aaggttgaaa ggaccaccag tcaggtcgtc agatgaggga acgatgacca acgccttttt
     4741 tatcgattag attagcttta ttatctcact agcatataat atctggatta tcatgagcga
     4801 catgaagaag aaaaagaaag cggagagcga gccgtcgaac aacaatcggt cggaccacaa
     4861 gggatccaag ccttcctccg ccgcggtagg agaggtcacc ggatccaaga agaagggcaa
     4921 gaagtaattt ttataaatta tccggcgaga tcatatctgt tagggttttc tcgccaaccc
     4981 ttaattttca ttttttgata gaaagggaag cgccgagggg gagattcgaa ctcccggggt
     5041 actaggtacc accggctttc aaggccggcg ccgtgatcca ggcttagcta cctcggcttg
     5101 tttaaacgat tttttctccg cgcccggaca tgaggtcctg caggtccagc tcgaaagcga
     5161 ttatcggata gccgatctcg taggcggtta tgacctgggg gtgcagctca ccgaagtgac
     5221 cgacggtgcg gccgttgacc tttatcatgg cgcagcgccc gggaatgaac atgcccagat
     5281 cacccgggac caatgaacat tgcacgccca gctccttcag cacgccctcg gcgagcgact
     5341 tcatttcggt gaacgaggcc ttggagtgta cggacatgac cgccatatgc ttccggcgct
     5401 tggcgtcgac gaccacgtcg ccgacctcga atatgcgttg cggcaggtcg cggtgcttgc
     5461 ttcggcgaag tacggtcaac agcgaaggta tcagctgcac gcgcaggcag ttgtggtcct
     5521 cgctcacggg gttgaggacc tccaccgcct ggacctccgg gtacggcacc ttggagaact
     5581 gctcatccat ggacgagagc gtgagggtgg tgacctccca gtggccgtaa ccgaccatca
     5641 tctggcgcac caggtcggcc accttctcca tgcggcgctc gccgccgatg gtgcgggata
     5701 ggggtttgga atttccgaag ttctcgtagc cgtaaccgat ggccacgtcc tcgacgacgt
     5761 ccgcctggtg aatgaggtcc atgcgcaccg gggaggagga gaccttgacc ttgcggccct
     5821 tcggctcggc ggagtagccc atccgggtca ggcactggca catcgccaac ggctctaggt
     5881 ccagtcccag ggcggcgttg gtcttgtcaa cgtccagaag ccactgcttc ggacggaggt
     5941 tgggggtcat gcccttttcc tcgccgcgca gggtgatggt ctctatgacg ccaccccttt
     6001 cggctatgga ggtgcaaacg atgttcaata cgccgctgat ggtgttctga tcggtgccgg
     6061 tgacgtcgat gaacaggttc ttcgtctccg tggtcaccgt ggtcaatcgg ccgttgatta
     6121 tgggcgggaa cgacaggacg tcgtttttag cgtccagtat caccggataa agctccttgc
     6181 catccaggag ctgcttgtaa tccttgccct tctcgtgctt ctccagcact tcggccaggg
     6241 tcatcatctc ttccttggcc aaggggacga atgagatgga tgtcggcgaa acagccttgt
     6301 aaacgaaggg aggatgcacc ttgtccagat cgtggacgcc gatggccacc ttggccctct
     6361 ttcgcccgac cgtgagatgc aatttttcct gcagttccat gagggagcgg atgctcttgt
     6421 cgtccaggac cacgcctcgg atgaccgctc cgaccacgta gggacgaacg ttcttgacgg
     6481 acggctccac cctcatcacg atgtcggagg cggacatgtc gtacgttcgc atcccaagct
     6541 cgatgtcgaa gaaggagcgc aacgcccttg ccagtccttc gaccgagtac aggtccggcc
     6601 ggttggggaa gaactcgatg gaggcttcct tggtcaccgg gtcgaagtca tggaagtccg
     6661 ctccgatcat cgggatgcgg tccagtacct cgcggtcctc catcttggta cctatgaggg
     6721 acttcaagtc ctccaggttg aagttgatga ctggcattgc gttcgcacca tggggtagaa
     6781 ggtataagag ggtttttaat tgaggcggga tgagggaact taccttccca gagccttgtg
     6841 ggccttgccc agctcgccgg ccgattgggc ggctaaggtt gaaagctcac ctgctaggac
     6901 cagcgcggcg gcgatctccc ccagtttttt ggctttgcca gttccgaggc agtccatcat
     6961 cttgagcgct tcgctctggc aaggcaattt ggtgcctccc ccgaccgtgc ccacctctat
     7021 gcatggcaaa cgtacggaaa ggtaaacgcc ttcctcgcac agttcgcacg tagtgctggc
     7081 catgctgcct tcgacgacct gtgcggcgtc ctgtccggtg gcgatgtaga gagccgcaag
     7141 catgttggcg gcgtgggcgt tgaaaccgta cgatagggac atggagcttc ccaccaggtt
     7201 cttgcgatag caggtctcga ccatcgcctc cggggtggtg tgcaacttat ctttcaccag
     7261 atcggcaggg atgcgcacgt cggccagaac agtttttccg cggccgtcta tgaagttcat
     7321 cgccgacggc ttcttgtcca cgcacatgtt gccggagacg gatatcagtt tgacgctggt
     7381 cctctcctcg ataacacggc aagcggcctc ggtggcgatg gtgcacatgt tcatgcccat
     7441 ggcatcaccg gtatcgtatg agaatcgtag gaacagagag cgtccggaag cgaaggcgcg
     7501 aaccttggcc agctttccgt gcttggtggt cgcttcggcc accgccttga gctcctcgaa
     7561 gttctcgttc acccactcga ccacccgccg gcagtcccgg acgcccttgg tgcggaacac
     7621 cggcgcacgg gtcatctcgt ccttgattat gatgacctcg gcgcctccac tggcgctgat
     7681 gatcgaagcg ccacggttga ccgatgcgac cagagcgcct tcggtggtag ccaaaggcac
     7741 caggaactct ccgtcggcat ggtccccttt caccttgagg ggaccgacga agcccaaagg
     7801 cacctgtatg gtgccgatca tgttctccac gttcttttcg gcgagaacgg gatcgtagga
     7861 gcaatgcccg gcgtgctcca acctagcgcc ggtgaacgat tcgacggcct ttcggcgatc
     7921 ttccatgtcc gttcgggtct tgcccttgtt cctgagaccg tcgtgggagc tcatcggcat
     7981 ggaatcaagg tcgtattaga taaccttcac gtccttcccg aatgatgaaa agacggttca
     8041 atataaattt aagtaaaccc gaggataatt aattaaaggc tatgccttaa atttggttta
     8101 cccgctcaaa ttagttttga attctactta tagttacggg ttaagattta atatcagaag
     8161 cgttaatgcg gcgaaatatg gtgcggtgca cctagagggc gttaccagaa atgtacacta
     8221 tgagtcctat gtcgggcaag cttcttagcg acgaggaagc gatggtgaag tacgtgaagg
     8281 ataaccagtg gggactggct accgcgatcg atctcagaca ctgcgatcct cagaagatcc
     8341 gcagcaagga ggtcatcacc cagttcgcca tcgacctttg cgattacatc aagatgaaca
     8401 ggttcggaga ccctatcgtg gtccgcttcg gccccatccc caaggtggag ggatattccc
     8461 tgtgccagct gatcgagacc tccatgatct ccggccattt cgccgaggac accgagcgcg
     8521 cgttcctaga cgtgttcagc tgccgcgagt atcctcctaa gaagaccgcc gagttctgca
     8581 agaagtactt cggcgccaag gagatggaat actccgtttc cttccggaac taaaacgccc
     8641 gcctgaatca caggacccaa atgatttaac gccccagctg cggcccccac cgcagtctgg
     8701 tatcaacttc ttccctctta ttatcgctgg catgatcatc ggggaccacg atttttcctt
     8761 tgttccgggc catttccagg ccaggaccat ggaaaggttt aaaattgaat gccgcattcg
     8821 ccaatccact tgggcccata gcttagcctg gttggagcgc ccggctgata accgggaggt
     8881 caggtgttcg aatcaccttg ggcccatcca tttcactggc tcgtccgaaa attttccgtt
     8941 tttggaaaat gtttggacag ccccttcatc tattgactgg atgaaggagt catattcact
     9001 gaggacggct gcttgatcgt tggcattgag cccaagatat ctgtaggtca tcccgggagt
     9061 ttcgtggcct aatatttcag acgtgtatgt ggccaacaac tacgctaacg atactaactt
     9121 cgatctcaag gtgccgttcg agattcatgc ccttgagtcc ttcgggatcc tcattccaga
     9181 aaacaagccg gaactgaagg cggcgatgga tatagtgatc aatgttttga tagccgatgg
     9241 aactcgggat gagattatga tcaaatagct agtttagtta taatctaaaa ccatttattt
     9301 taatttttta acacgagaag aagtgagttt caattatcct tcagtcagac aaacaataaa
     9361 aggctcgttt tgtgttttaa caatttctag agcaaatgct ctaaataatc tcctcaataa
     9421 tattatctct tggtccgcca taatttcatt tatgctttaa taatcagctt ataaggatga
     9481 ttgaggcctt cagcagttct tctaattctg tccctgaaat catctagctc attcatgttt
     9541 tttggactgc aaaccacaac gatgacacaa tgaaacgcat ctagatgacg gaatatttgt
     9601 ccaaatgccc gatcgtaatc tggacccctc ggagacttct tgacctcgat tggatatttg
     9661 tgatccacta agatgtcgac taacgtttcg ccagtatcca tcctggtatg atgccctttt
     9721 ccagccagaa acatattcaa ttcggctcta taaccatctt cggttgagta tgatttagat
     9781 ggtatccata gttcaatttc gctaatgatc gactcgaaat ctgcattggt catcgttttt
     9841 actggttctt tctttcctgt gaacagagga attactggag ctggtttaac ctcttcttta
     9901 ggatgcacct tttcctcaaa gttttcaaaa ccgaacaata tgtgcaacaa atcgttaatc
     9961 tgatcatctt tacttctacg cttagggata tcataagcgc tagcgatgtt ttgaagcgcg
    10021 taaccatcca atctgttcag gatcatcttg ggcgatcttt catttgcgtc catgatcctc
    10081 agaacaacat cttccttcct tcctgaaact ggaagatcct gcctcagcaa tacagtttta
    10141 agcgaatctt tgtccacctt gttcaggact tcgaacaatt ttctagagat atcatctgta
    10201 agcgttttcg tcggatccac atcaacgggt tgctgttgag tggccggaat ctgttgaacg
    10261 attggaggaa gtccgaaata atttgttaac agttcattaa tttgctcgtc cttcaatcgt
    10321 tttctttgca tcccaatttg ggatgccaga tattgaagat tagctaggtc gatgagaggg
    10381 atgattgctt gaggatttcc ctcctgggag ttgattaacc taactacgat ctcgtatttg
    10441 ttaccagaaa ccgccaaccc caatttgaat agtattgatt ggatcgaatc cttgtctagg
    10501 ttcatcaaca tatcaaacag tttctgccgt ggaacgtcca agaaaggatt gagcaattga
    10561 gcaggagcaa cgttgatttg ctgagccatg ggctggggat aaggttgttg agatggtgtc
    10621 ggataagcgg gtttggaaat taccggggaa tcttcctgaa caatttccct taggatgata
    10681 ttgacaagtt cggtttttga tgcgaaaccc atttttgata gcagccctgc acttgttctt
    10741 tcattcctaa caatattgac tagcaccgtt tgtggtaatc tggtaaggat cggtgcagca
    10801 tttcccttat taaattgtct ctttatcaat gccaacattt cgcgttttga accattagag
    10861 ggcattccgg aggacctcat cattatcgaa atatcctcct tggaagcata tttgtctatt
    10921 acatcaacga gctgcatcac ggcacattaa gtggttgatt taaattaaga cttactgatg
    10981 aattcgcaca aaataaatat aaatttatta ttcttgccac ccaaaattgt agcgcgaata
    11041 gataatttga atcacgggaa gactttttct cactacggca tacgatgagt gaggaggtgc
    11101 agatgcctag agataataat tattacacct caatattaaa atgttagtgc tataccgttt
    11161 gaagaaaaca gtaaaaacag taactatttt tttccgtttt ccagagccag catattgaag
    11221 aaaacagtaa aacggtaact atcttttttt atgagaaaag aaaatgataa aaaggttagt
    11281 cggaaccgcg aaacggttcc tttcttcctc ctaaggcaga tttccgattt cggaaaaatt
    11341 tgagccgagc cagcaatccg aatgagcctt aatcacctgg gcccatccat ttcatttctt
    11401 ctcgtggtcc agttttcaga ttgaatccta ttttccaaac cgctgcccta ggtatctggt
    11461 gatttgacaa ttcactaata tgggatttaa ccattctagt tcatggtccg gggcatttcg
    11521 acgtccaggc gctttcttct ggtgctcggc cttgtcgccg ctttggccat agcctcgtcc
    11581 acgatgtcga agaacccggc cctaccgctt ctcgcccttc acataggcgc ggacgatgcc
    11641 cagatcgggc tgatcgccgc catcagcccc atccctggga tcctggtaag tagcatcgcc
    11701 ggcgcctatt ccgaccgtca tggacggacc aggttgatca ccctgtcact tctgatattc
    11761 gcctcggccc cattcctcta tctgttcata acggaggtct ggcaacttgc cttggtccgt
    11821 ttctatcacg gtttcgccac cgctatgttc atgccggtgg ccatggccgc ggtggccgac
    11881 cggttcgaat cagctaatag gggcgaggcg ctcgccactt tctcctcctt ctccttggtc
    11941 ggacggttct cggcgccttt ccttggcggc gccctgatat attataccga tttcacttcc
    12001 ctgtacgtaa ttatcggcat atccgccgct attgccctgc ttttctccat catcgcgcca
    12061 tggaaagaga atgatgtgac cgcgcgtgtc aagaagttcg aagggaccac ggtctccgcc
    12121 ctgaaggaag tagtcaagga acgcgggatc gtgctcacct cgtccataga ggcggtgcag
    12181 tactttgcga tgggcgcctt cgagaccttc atcccggtct atatgcacca ttcgatggga
    12241 tcgaccgccc tggagatcgg tttcgtcatg ggaatacagg tagtggccat gctattggcc
    12301 aagccgatca tgggaagggt ctccgataaa cggggaagga tacctttcat cgtcgtcggg
    12361 ctattactag gggcggtcac cataaccctc atgccttggg taagcgacat cgtttcgttg
    12421 tcgttattgt ccatcgtctt cgggcttacc gtggccacgg tgactgcatc gacttccgcc
    12481 ctggtcactg atatcgccgg aaagtcggca catggtagct ccattggagt cctgaggtct
    12541 ataatggatg tcggccactc caccgggccg ttcgtcaccg ggatggtggt cggggcgttc
    12601 tcctacactg caggattcgg cctggccggg ggcctattgg ccaccggtgc cctgctcttc
    12661 tccttgggta tgcgctcaag ggatcgaccg aaaggaatgg ccccgtcatt gtaaacatga
    12721 ggtttaggga ccgagatgat taattcactt ggcgacattc ggaagatgat gaatgagaaa
    12781 ggtgggccga agatggggac ggaacgctcc ctgaagcagg tgcctcgccc agactatgcc
    12841 actaacattc cgggattcgt cattcgattc gccgaggtgg acgatgtcgg actgatcctg
    12901 gatttcatta aaaggcttgc cgagtacgag caactggccg atgaagttgt cgccacggtt
    12961 gacgtgctgc gtgattccat tttcgtgaaa catcaggcgg atgtcatcat aggtgagctg
    13021 aacggaaggc cggtggcctt cgcgcttttc ttccacaact tctccacgtt cctaggaaag
    13081 gcgaacctct acctagagga cctcttcgtc gacgagagct gccgtgggct tggattgggg
    13141 aagatcatgt tctcctgcct ggcgaagatt gctgtcgata gaggatgcga ccggctcgac
    13201 tggtggtgcc tggattggaa cgagtctagc atcggcttct acaagagcat gggagccgaa
    13261 cctatgtcgg attggaccgt ataccgggtg gatggagatc ggttaaagag attggccgac
    13321 ctgctctgac cgctggaaca cgggacggta gttctcagcg cttgtctatc ggaacgaacg
    13381 gcctcccgaa ctccccgacg tagttcgata acggacgcag gagaacggca tcctcgtact
    13441 gctcgatgat gtgcgccacc caaccgacga tcctgctggc ggcgaagaac ggggtgtaat
    13501 agtccttggg aatgcccaag gcgtccatgg ccaccgccgc atagaagtcc acgttagggt
    13561 agatgttctt cctctgatgg acgatgccct cgatcctgga gcacttgttg tacagctcca
    13621 tggtcctctt ctgattgcat aggttctgca cgatgtgccg caggtgcttg gtccgaggat
    13681 cttccgcccg gtacacccgg tgtccgaagc ccatgatctt cttaccatct ccgagaagac
    13741 cgtagatgta ctcctcgacc tccgcctcca ggccgatgtc gtccagcatc tccatgacct
    13801 tctggctggc cccgccgtga atcggtcccc tcagggtccc gatggcggtg gtcaccgccg
    13861 aatacatgtc ggcgttggtg cttgccgtaa ctcgcgcggc gaacgtggag gcgttgaagc
    13921 catggtcggc gtgcaggatc atgatccggt gcatgacgtc cgcctccgcc tgatccggaa
    13981 cgcgtccgtt gaacagatac aggaagttct ccgcgaagct gaggtcggga cgaggttctg
    14041 ggacctcttc gccctgcctg gtccggtgga tggaggccac gatggtcggc acctgggcga
    14101 tgagcttcac cgccttccgc aggttctcct ccggagagat gtccagcacg ttagggtcga
    14161 actcccccag attggagacc tcggtgcgca ggacgtccat gggatgtgcg cccttcggag
    14221 atagcctgat cgattccacg acatcctcgg gcaaccgcat gttcgatatg agctcggaat
    14281 tgaaggcgtc cagttcctcc ttgttcggga acctcttgtg gatcataaga tacgccacct
    14341 cggcgtagac cacgtgaccg accaggtcgt cgatgtcgta gcccagatag tatagggagc
    14401 cggagggatc gatgtaactg atgcgggtct ctgcggcggc cacgtccttc aatcccctga
    14461 tcacgtcctt ggaactgttg ccggtcatgt cacatcatcc tgtagagttc ttgcgcaggg
    14521 acggacctcc gcccgcaagg tctcatatgg gtctcgtaaa ctggacatcg cttaaaatct
    14581 tttttatgtc gggcgatggt tcagatgatg ggccaataca gtcgtgtctt tagcttgtcg
    14641 ggcggaacct cctgcgggtc gttaaggtac tcctcccaac agaacgatgc tggcatatgc
    14701 ccgttgacct tcatccattc ctccacctcg tggtaggtat ccgtgagctt atcgtaggga
    14761 ccgatgtgca tggccacggc ggcgcggacc gccggaagcg tgatggtctt tacattcccg
    14821 gactccactc ccttgccgac aatggggaaa ccgacctcca tgtccgttac ctcgccctcc
    14881 cagctatgat agagcgtgaa gggaggaccc acgcaatgga cgcccttgcc cagatgaggg
    14941 tagagctccc cgaacatcct ccctattgcc gcaggaatct cgctcacctt gaccttctcc
    15001 ctcaccgcga tggcaagggt ctccttggtg ttgaccacct tgatggatgt catgcctatc
    15061 aagaaaaaaa ctagaacgaa gggagataaa ggatttggta agaggatggt gaaagtgttt
    15121 tcggcttaca tcgcctcgta gggaagcgct ccgtggtcga tgtccctctc cttcttctcc
    15181 gccgcctcga tgtcctcgtc ggccatggag cgcttcagca cgcacacggt gcgctgcagg
    15241 gcgatgatgt catcgagcat ggactgggcc acccatacgg tggatagtag ctcctcgaac
    15301 ttcttgtggt gggccatggc ctcgatctca tgcaggaccg ccgggttata gagcgtgttc
    15361 cggttcaccc gaccgagcga tgaaacctca tcgatctgcc tttcgaaggc gttcagctgg
    15421 ttggagtaca tctcctgcaa taccttgagg gccgcgatct tgctcgcctg ctcttctgtg
    15481 accggggtct ctaccttctc ttttttcatg ttctcaccag tgcacgtcaa cataacgtta
    15541 agcggaccag ccaactgtgt tcgacatcat atgcttttcc cggtgacgcc caccagatag
    15601 gatattaatt ccttcaacgt tcatggggcg ataacatggc ccgagatttc agccagaggt
    15661 ccagctccat cgtccaatcc gagataagga acatgacctt ggaatgcacc aggctgggag
    15721 ggatcaatct ggcccagggg gtctgcgaca cggacacccc ttccgaggtc attgaaggag
    15781 cgcatcgagc cgctcttgat ggagtgaacg cctacacccg ctacgacggg ctcccggtgc
    15841 tccgaaacgc catagccaag aagttcaagg acttcaatcg cctggacatc gatccggaag
    15901 gggaggtcgt ttgctccgcc ggcgccaccg gggcgttcta ctgcgcctgc atggcgctgc
    15961 tgaacgaagg cgacgaggtc atcgtcctcg agccgtacta cggctatcat gtgaacacat
    16021 tgctggccat gggcgcagtt ccgaagttcg tgagcatgca cccgcccgag tgggagctgg
    16081 acctggagaa ggtcaaagat gtaatcggac cgaagaccaa ggccatcgtg gtcaacactc
    16141 cctctaaccc ctccggtaag gtcttcgacc ggtcggagct gaaaggtttg gtggacctgg
    16201 cggtcgacca cgacctattc atcttctctg acgagatcta cgagtacttc gtctacgatg
    16261 atcggcagca cgtttcccct ctttcgttcc aggaggcgag ggaccgggtg gtggtgatct
    16321 ccggttattc taaaacgttc agcatcaccg gttggcgcat cggttacgcc gtctgcgaca
    16381 agagatgggc gcgcatgatc ggctacatga acgacctggt gtacgtgtgc gctccggccc
    16441 cgctgcaggt aggcgtggcc aagggcatcg aggagctttc gggtgagttc tatcgtcgcc
    16501 tgtgtcagca ataccaggga aagagggaac ggatggtgcg cggcctccag gaaggcgggc
    16561 tctatccgta cgtaccgcag ggctcctatt acatactggc cgacgtcagt tcggttcccg
    16621 gagatgattc caagcagaag gccatgcaca tcctgaagga gtgcggggtc gccagcgttc
    16681 ccggttcagc gttctaccag cagggcggcg aggacctggt caggttctgc ttcgccaaga
    16741 ccgacgatgt cctgaggacc gctaccgacc gactatcaag gctgagatgg taggaggcat
    16801 tccttctccg tctccatgtg aatgctgacc actatcccag gtatcttctg taagagggct
    16861 ttttccaggc tttcggtcag atcgtgagcc tcggccatgg tggtctgcgc cggaacgcag
    16921 acatgcattt ccgcgtagac gttatagccg acccggcggg tcttgagatc gtggtattgc
    16981 aggaaaccgc catgctcgtt gagcaccgat tctatgatcg cctccgactc cgggcagctg
    17041 tggtccatga ggtcccggca ggtcttggcc agaacggaat aggccatgcg caacaatagg
    17101 atcgccacga tcaaggccat tatcgggtcc agcacgtacc atccggtcat ctcggccagg
    17161 aacaggccga tgacgatgcc tacggacgag atgacgtccg aaagaagatg cttggcgtct
    17221 ccctccaggg cgatcgagcc gttctgcttt gacgaacgca ggagcagaaa agacatgccg
    17281 ccgttcaggg cggtggccac cagggagacc atcagcgcca gaccgatgga tgtgaaaggc
    17341 tgggggtcta gcaatcgacc agcgctagcc agtaatatga gcacggcggc gatgacgatg
    17401 agaatgccct ccaccaggca ggatatgttc tccgccctct ggtgtccgta gcgatggtcg
    17461 gcgtcggccg gcatcatggc cacgcgtatc gaggccagca tcattatgga agccacgatg
    17521 ttgactatcg attccaaggc gtcggagagc aaggcaactg agccagagat cagataggcc
    17581 gccagtttaa tgaagaatat aagcagacct ataccaaccg ccagcttagc gacctgctgc
    17641 tttttcacag cgtagggcag ggtcgaagcc cgataaaggg tttattgttg ctgaagcctt
    17701 gaacgaccgc ctatttctcc gccagagcct tctcgaagag agcgtcgacc tccgattcgc
    17761 tgagcttggg gtcgtgcttg acgaagaagg tgagaaagct ctggtcctcg gtgtagatga
    17821 cgcgcgaagg acgaatgttg acgctaagca agacctcccc ggtctccagc atcacgtcca
    17881 cctgggtggc cgccttgccc cccttgttct tggtgcggga gagcttcatt atgctcttgc
    17941 ggttcgcctg atagaggcgt cggatccggt catccaatcc tggtccttcc acgttgcgag
    18001 aacgaactag aatatgaaaa ggttgctccg gcgaccgggc gaaccttgag aaccatggcg
    18061 agaatgataa tttattgcga aagtgattta acccattcgt ccacttggtg aatggtgaaa
    18121 agaatggtaa gcatgaagga tatcatatca aagtcggtcc tgacgttgga cgcctataat
    18181 gttggagcgg tcaacgactt ccaggtttcc gtggacgatt ggggcgtgaa gatgatcggg
    18241 gtcacattga acgcccagtc caagaaggac ctgggcatca agaagctggc cctgaccgga
    18301 ctgaccctct gcatccctat cgagcacgtg gacaaggtcg gggacatggt gaccttgcgc
    18361 atcgacttcg atcatctgaa ggacctgccg gagtgcaaga acctgctcta aacacctttc
    18421 tatttttcca agcgaagcat taattccgta ggtgagcatt ctcgggcgaa acctatgtct
    18481 caaggaccga tgaacgccag actgatctac aagttctttg aggctgccaa catgcagcgg
    18541 tggaacgatc atatccgccc cgtggagctc acggagcttg acaagcagtc gcacaagatg
    18601 gtcatcgctt acgttctggc ccggttcgag gagaccgaga agggcaccaa gatcgattgg
    18661 accaggatca tcgagggcgg gatattcgag ttcctgcatc gcatcttcct tacggacctc
    18721 aaaccgccgg tgtaccaccg catgcagaaa gagaagggcg gagagctgaa cgagtacgtg
    18781 ttccgcgagc ttctttcaga ggttccggac atcgaccagg attttttcga gcgcttcaag
    18841 gcctaccatc ttcacaagga cgagagcgtg gagcggcgcg tgctgcgagc cgcgcattac
    18901 ctggcgacga actgggagtt caagctggtc tataacgcta acccgaccat gctgggcata
    18961 gaggacacca agaggagcat cgagatgcag atcgaggacc attacgacct catcggcgtg
    19021 cagcgcataa tgctggccaa gaagtcctac gggttcattg agttctgcgg tcagttgaga
    19081 tatcagcagc gctgggcccg agccccgcga atccctagaa cttccgttct gggccacatg
    19141 ctcatggtgg ccatcatgtc atacctttgt tctttgagga tcggtgcgcc agcccagcgc
    19201 accgtaaaca acttctacac ctcactgttc cacgaccttc cagaggttct gaccaaggac
    19261 atcatcaccc cggtgaagaa gtccgtggga gggctggagg agctgatatc gaactatgag
    19321 gagcagcagg tggaggagaa gctgcttccg ctgctaccgg ccacctggag gaaggacttc
    19381 gagcaattgt tgatcgatcc gttccgcaac cggaacaggg aggacgggtc ctgggccgtc
    19441 gatggggcca tgctcaaggg ctgtgacaat ctggcggcgt tcatcgaagc caactcgtcg
    19501 ataaaatacg gcgttagctc caaggtgctc aggatcggaa agcagcgcct tttggagatt
    19561 tatcaggaca atggcaacat cgccgggatc gacttctacc agctgatgca ggaactggac
    19621 cacatggaca tctgatcacc aggtgacgcg tccatcgaac aggcggaaca gcagatcgcg
    19681 gtaatacttg tcatacggca gggtgaatgt cagctccagc tcctcggcac ggatgtttat
    19741 gacgtatttg ccttcgtcat ctccgtcata cgaaaggcgc accgacgtca cgtcggaggc
    19801 ctcgactgaa aaattatcct tggtctccac caggacctct tccggcgaca tctcgtagaa
    19861 ccgggagacg ttatcgctgc tgctggagcc aggcatgaat atgcctgctt ggcggagctc
    19921 ggccttgccc cggtcgagct gcacctcctg aatgcgggcg aagatgagct tcccggaggt
    19981 catggccatg gcgaagacgc cttggcgtcc tacgatgtat gccggagccg ccactgaggt
    20041 gacgatctcc cccttggccg gttcgaaacg ctccatctcc tcggcgacca tcggctgacc
    20101 gcaatagggg cagaatcgca tgtcctccag gagaggcttt ccgcacttgg cgcaggtcgg
    20161 catcatatta tcggtcatat atccagaggt atttatggac ccatcgcctt atcttttttc
    20221 gtcataatgg atactggcat ttttcttctc ggcattagta tgacaaaata tgacaaatga
    20281 cagacgtttt aaatagttag tatgacaatc ttattttcag cccaagccga ggagatctaa
    20341 cactatggag ggagagagga taacgctgcg cctagaaggc gaggacctgg agctcatcga
    20401 tgatttcatc gaagggcacc cggagatctc gaaccgttcg cagcttgccc gtatcgccct
    20461 tcgcgcgttc atagaaaggg atggtggagc gcgggtgagc ggatcgggca agggagaatt
    20521 tgtcctgaat gtcccgccgg ccgtacgtag cataatggaa gggatggtgg aggatggcta
    20581 ctacaactcg gtggaggacg tcgtcgtgga atgcctgcgg aaggagttca tctccaggga
    20641 caacctggaa aaagtgaagg atgagcaatt tcagaagagc aggcagatca tggcaaggat
    20701 gtaaggaccc gctctggact agagcgcaga gggatgggat gcattaattc acttagcgaa
    20761 cgcgctgcga ggcgttttcg tggaaaacga cacgggggcc taaaaaatgg aagccggaat
    20821 aatggaacaa acggtcagga ccgagcagat agtttcaatg ctcagccgag gactggccga
    20881 acctaggata tcggtagtgg gctgcggagg tgctggtaac aacatcgtta acaacatctt
    20941 cggcagctgc aagaagaacg tgcagacggt cgccataaac accgacgagc gatcgctgca
    21001 gaaggtcaac gcgcacaaga agctgctcat cggcaaggac gttaccgagg gccgaggcgc
    21061 cgagggattc cctgaggtcg ccgagtactg cgcggagtgc gccaaggacg ccataaagga
    21121 cgccataaag gaccgggaca tagtgttcgt catcgccggg atgggcggcg ggaccggtac
    21181 cgggaccgca cctgtggtgg ctcagatggc caaggacctt aactcgatca ctttcgtaat
    21241 agcgatctcc cccttctcct tcgagacgga gagggtcagc aaggcccaga tgggcatatc
    21301 caagatcaag cagatagcca agaccacggt ggtcgtggag aacgaccgcc tgctgaacgt
    21361 ggtggacgag atgcctctga gcaaggcctt ctcggtcatc gacaacagcg tggtcaagat
    21421 aatcgattcg ttctgctctc aggtcagcct gtccttcatg aacgccttca ccgaggaggt
    21481 cgttcagtac atgagggctg acgagaagag cgaggtagtt cgcgagcagt acatgatgcc
    21541 cgagctagtg atggccagca agggtccggc tgagtctgga ctacggccaa tgggacagct
    21601 cggaccgatc atgcaatagg cccgcgaccg gtttccatag gctaacgtgc ggcggatgtc
    21661 agccgccgca ccacaccccc caaatcacct tccattgatt ctcaaaggtc ttatgatgga
    21721 gtgagccgtt cccgttctgt gctcctggga ctggtcatca accccatcgc cggaatgggc
    21781 ggtagcgtcg ccttgaaagg aacggacggg gacgcttacc gtatggcaat gatcaaagga
    21841 gctgttccac tggccagagg aagggtggtc cgcgccctga gacgcttgga cggtgacatc
    21901 ggatttctga ccgcctcggg agagatgggg gcctgggcat tgaacgaact aggtcttgct
    21961 cacgaggtgg tgtgggaaac ctctggggag agcgttcccg aagacacccg gcagacctgt
    22021 cgccgattct tggataggaa ggtagacctg ataatattct gcggcgggga cgggacggcc
    22081 agggacgtgc tcgacgcggt cggggataag gttccgatta tcggaatccc ttccggggtc
    22141 aagatgcact ccgcggtgtt cgccaacacc cctgaggaag cgggagacgt cgtgcagcgc
    22201 tttgtaaatg gcgaaacgga tacccgcctg tccgaggtca tggacgttga cgaggatgcc
    22261 ttccgtcacg gagagctgcg agcaagattg tacggatacg tgaaggtccc ggacctgagc
    22321 ggattgcagc cccccaaggg agcgttgttc ggaacctcgg acgaggagca gaaggaggcc
    22381 atcgccgagt tcgtggtgga aaggatggaa ccgggaacga tatatgtcct gggaccggga
    22441 accaccacga aagcagtggc cgacaggatg ggacagccca agacccttct gggagtggac
    22501 gtttacctgg atggaaaggc gatcttgacg gatgcttccg aggaggacct cctgcgcatc
    22561 ctgataggcc gaccggcaag attgctggtg acgcccatcg gccgccaggg attcgttttc
    22621 ggacggggga accagcagct atcgcctcgg atcgttgaca tggtcggcct ggagaacctg
    22681 ctcgttctgg ccacccctac caagctggcc gatacacctg tactgcactc ggactcgggc
    22741 gacatcgaac tggataggcg actctgcggt taccggaagg tattgatcgg ttacgaccag
    22801 taccggatgg tccgttgccg ttgaggggaa actgtttaaa gagctgggca cgatagccat
    22861 ggtatgagcg tgatacacct cgatttccgt acgttcggcc aggccaccga ggtcgaggaa
    22921 cgagtgagga aggccatgac cttctcctcc gggatcgagg acatcaaggt ggaacactcg
    22981 gaagggtatc acggcaacaa gatcctgata atgacctgca cggtttcgcg aaaggcggac
    23041 atccgctcgt tcttccgcag gctgtccagg gatgacctgt ccttgctcct ggatagcatc
    23101 gatcaacgca tggacgagga cgggcagttc tttttccgcc tggacaagca gaaggcgttc
    23161 caggaggaac tggtcatctc cagcggggac gactgcatcc acgttcgcgc gaaggtggag
    23221 agctacccca agcggaggga gaaggccttg gagaacgcca aggtcatgct gcaggagctg
    23281 ctcgaccgac aggctaaata ggaattattc attcggaaac gataggcagg ggtagccaag
    23341 cttggccaac ggcgtaggac ttaggatcct atccttagtg gttctggagt tcaaatctcc
    23401 acccctgcac caaacacctc acttgtcatc gctccttctc atcttgacat catcacggcc
    23461 tagcagaagc tggtattgaa tttcccgttc aatggctatc aaagtatgat tcgttgggtc
    23521 tgaagcccat accgctttcg ccgcgtacca ggcggcagcg atggaatgcg ttggaacgtg
    23581 agaagttgcc atggcctgac cacaggcccg ggcggcgaac tgagcggcgc ttcccggagg
    23641 catggaacgg gcggcggcat gagcgttcaa agacgcccgg cgcacctcgg tcatatgaaa
    23701 ttctccggtc ctggcccatt ccctaagttt aatgatggcc agcctcggac gttcatcagc
    23761 ggggaattcc ttctcgaaca agggcagaac cctttccgca caattcgcgg cccagatcgc
    23821 caaggtgcga tggtcactag acctggccag ccgatctatg tccgcgttga gcggatggtc
    23881 cacgaacctg ggcttggcca tgcctatgcc attcgttacc acatatgtca aatttaccag
    23941 ttattgtcgg ttccagacaa atattgccat caggaacaga cgtcgtgcaa tatgacgaaa
    24001 taattatcca aagcattaag ccgtctcaac cccacgtact gctcatggga gtcaccgaga
    24061 tcggagacca gaagaagtgt tccgtgtgca gcggaatgaa ccccgctggc gcggttcaat
    24121 gcctgctctg cgggtcctta ttgatgtgat ggtccagtga gatcgtcccg ccatttttaa
    24181 ggtacatacc agcttaggtc tagcaccctg atcaacgcgc gtttcgtttt ccgagcgtct
    24241 cctgcagctt cttgatctcc agttcctgga tctcgtccgc ggtcatcttg cctccgctct
    24301 tcatgatctt gaccacctcc gccgagggat tcgtgaaaac gtacaggttc acgttcttca
    24361 ccgtaccgtc cttgaaacgg tgcttgtaga ccagaggcag tttcaccgat tgcatgaact
    24421 cgctgatgct cagttcctgg tcgatatcct ggtcgtccag tacgttaagg cacatctcaa
    24481 gcgcgtactt gccgaaggcc agtatgttca actcgttctt tcccaggacc ttgagctcgg
    24541 acatgaagtg ctccttgcat ctggtggccg ccttgcgcca ttccttgttc acatcccggt
    24601 cgccgttcac cggaacgcat ttcagcgcat gcgtccagta aacgcgagac gcagagggat
    24661 cgaaaggccc gaagatctgg gcgaccttgc tcagcggatt ggctttcctg acctcgtcca
    24721 gggaaccctt gccgagcgtc aacgagatta gcttcgacgg aacaccgtcc cccagaggcc
    24781 gcagccagtg gccgggctcc tgggagacga tgatgaaatc aactttacca gggtccttgg
    24841 gctcgaacag cacggggacc ttctgaggat cgcgggggca tccctgacat cgtccacgga
    24901 cgttgccgga gacgccggcc caacctcctt cctgggcatc catgcgcatg tatcagcgaa
    24961 catcgattaa actgttggtc gataaattcg tccggtgatg gaaggacgcc ttcatcgaag
    25021 cacatcaagg gcgataattg gatatgccta ggtgacaatt ccatcacgat aatgatggaa
    25081 cgccacatcg cccgcaagaa ggtcaaggag ataatgacca gtgaggtggt caccataacc
    25141 ccggagaccg acctacggac cctcaaggag atgttcgaga gatacgatta caacagcttc
    25201 ccggtcctgg aaaaggggaa gatggtcggc atcgtttcta agctcgacct gttgaaggcc
    25261 ttcagccccg ggttgaacgt cagcgtgagc cgggcgttga agttatttag caaggacgcc
    25321 gcgggcatca tgcacaccgc caccgtgttc gtgtcccctg aggacgacgt ttcaaaggcc
    25381 gccgactaca tggtggagtt caagctgcgc agcgttcccg tgctggagaa aggagtccta
    25441 aagggaatgg tctcccggca ggatatcatt cgctgtctga aggtcgagtg agcttggaac
    25501 ccttcctccg gttatagagg aagtacagga caaggatcgc gccaagccca cccagcataa
    25561 ggatgtccag atgaaggctg tccgtcttct cccagaactt gacccattcc cctcccagca
    25621 agtaaccagc cgtcaccagc acggtgttcc ataccagagc cccggagaat gtgaacgcca
    25681 cgaacttctt acggtccatc ttggacagtc cggcagggaa ggaaatgacc gaacggattc
    25741 caggaagtga gtggccgatc aatatgcccc agacgcccca gcgcttgaac cagcgctcgg
    25801 cggaggccat cttttccccg tccaacccga agaacacccc gaaacggtcg atgagcgggc
    25861 gtcccagcca caaggctagc atatatgcta ccgtggaacc gaccactgcc cctatgcttc
    25921 cgatcaatat caccaggaag tagttcagtt cgcccgtgga cgccacgtaa ccggcgaagg
    25981 gcattatgag ctcgctggga atcggtgtga atatcccctc tatgagcatg gctaaaaata
    26041 tacccaaata cccagtggcc tcgataaggt cgatgatgat ctggttgagc gtctctatga
    26101 tcattacaac tcacgtgccg gccttttcgg ttatcgttcc ccagtattaa taaactgcag
    26161 ggaaccgctc aatacgccga tctcacgacc gtaacatagc aatgactata tgctctgtga
    26221 acagagtata atcgatgagt gatacgaact tgttgagctc cttggggcac gcgtccgtag
    26281 tgcgcgttct ggagaagacg gccggtttca acggtccggt ggcggatgag gtggcgttac
    26341 gcgtattgaa ctactttgga tatctggacg agatcattga caacgctctt gatcatgacg
    26401 accgccgact tttctacttc ctgcaggaca tgaagatact caggacccgc tgggaggaga
    26461 cgcaactggc tagcggccgc aactggagaa tattttactg gtccttcaac tgggagagca
    26521 tcagccaaat attggaggat aaacctccca ctaacgaaac agtggacatc taccgtagcc
    26581 tgcccgattc ggcctggtgc cgcgaaaagc aagaaggcac ggcccgaggg aaaacgatta
    26641 ttcccagtaa ccggatgacc gttacatgaa gttctgctat tgccccgact gcaaggacct
    26701 gcagcccacc gcctggtaca ggcgtaaatc atgcaagctg tgcggcgggg attgccggat
    26761 catctccgtg ccgatgtatt actacggggt ggcgatgtac gcgctgagcg cggtcggggc
    26821 cttcctggta ggagctgaga tacttcgtta cgaccttggt ctgggagacc tgaggctata
    26881 cctgatgttc ggaagcctga tagtggccat gatcttcgct tccctggaga ccgcccgggc
    26941 ggtcgagatc gcccagaaga aggtcggcaa ggtcctctag accgtcagga acatggtgga
    27001 gacgaccgaa ccgtccccca gctcccgccg atcggcgtat acgtctccga cctcagcgga
    27061 aggatcagaa ccgaaatgca gaactgccga acctaggtcg atgaccagcc acgtatttcc
    27121 aaaggtcatc tccagctcgg tgatggtccc gttgaccatc ttttcgatga gcagtacctg
    27181 ttcctcctcc ggagccccga tgatcgaaag ggctatcaga tattccgcca gggtaacgac
    27241 ggacatggaa cttccctcgt ttgcagaaac ctccccggcc agcatcacag agtgatagga
    27301 cctcagcctt tccgttctat cttcggacat ctttccggga gaggccgagt agataacggc
    27361 gatcaacaac gtcaggacca ccaggaatat caaggcgtcc accaggacgg ccatccctct
    27421 acggtccttc ctcagcgcca tacccgcacc tccatcactc cggggaactt agtcccgttc
    27481 aattcgatga gcaaaggacg ttgaaaggcc aggacgtccc cggttgactg ttcagcctga
    27541 ttcagaacaa aaaggggcgt ggagttcccc gaagcacgat agacgatggt cattccggag
    27601 atcccctccg gaagaccagt taacctcgga cctacgcccg gtccgtcaag ggaaacgacc
    27661 tcgtcctcga agtataggtc attggaaatc agccaggaca tcacttcctc ctggtcgatc
    27721 tcctcttcca cctgcaccgt cccggaggcc aacaccacca ggaatatcga ggaggcggtt
    27781 atcaccacca tcactgccag tatcgattcc aagaatccgc ctacaccttc acggtccatg
    27841 cacctccttg ccacacgcac ggaccttcag cgatccgggg ggtataggcg gacaccttta
    27901 actgtaggct aactcagaac acgcccttgc gataatggcc taggctacta cgcccgcatt
    27961 tccgccgcag ctcctccagg ttggccatgt ccagttcctt gaagctcttt ccgacgaagg
    28021 ccgccaggtc ggggtgccgc cttctgacgt cgatccccag cgagtccacg cccattgtgc
    28081 gaagctcagg caccttgtcc agcatgagaa ggtccgtact gtgcaggatg tgcacgaacc
    28141 cttcgggatc gcggtgcacc ggatagcgca cgccccggtc gtccactaac gtgccttcgg
    28201 gcagcgtggg gtcccggctc agcatcaact ccaggcggcc gaaggccatc acctcgcaac
    28261 gtccctcggt tcgagagagc acgtgaatga gctcctcctg gttcagctcc ggcgataatg
    28321 tgcattggtg cagcttcggc aaggtgtagc tgttgaagaa gttcatgtgg tatgagccgt
    28381 agacggtacg ccccttgttc agctcatact ggtcgatggt attcaccatc acccggtcgt
    28441 ggtccgaagc ggattccttc aaagagagac ggggaagcat cttcacgaac tccttgccct
    28501 cgctcgcgca tatctcctcc gcttccgcgt ccaccttcgc cccgtcaaaa tagacccggt
    28561 ccgcgtacgg cagaaccgac ctcagcacgg ccaggctgga gacgtagaac gaaagctcgc
    28621 tcaccgtctc gccgcggcgc ctgcgcttgg gtggcagctc cactgtcttt cgaaccgctt
    28681 cccgctcctg taacccgatc ttcgatatca ggtcctcgat gaccgggagc tcccggtcct
    28741 tggtcttgta gacggtgtaa tccccgtcct tcagaaggaa gggcggagag gcgatgacgt
    28801 tcgtgccatc caggtcggaa cctttcaggt cgaagccgcc tactttttcg ttaccttggt
    28861 aaagactgat gccgtcccct gcgcctaaag cacctcgggg catcctcaga cggccctttt
    28921 cgacctgggc cggccccaga ggccttccgc gggattccgg gtgggcggtc tgcatgacct
    28981 cttggtcggt aagataaccg cccgagaaac cgcggttgaa aacgacctcc agcatctccc
    29041 gttcccggtc ggtgatgagc ggcgtctccc cgttcttggc cctctcgatg gccttcttgt
    29101 atatcttgga cgtcagatag acatactgag gggagcgcat tcggccctcg atcttgaggg
    29161 aggtgacccc gcaacgcata agttcgggaa tggacccgat cccgaaggtg tcagcggtgc
    29221 tcagcaggta tccttccttc tttccgagcg tgtacgattt gcggcagggc tgggcgcaca
    29281 tgccgcgatt gccggaacgg ccgcccagaa agctggagaa gaggcattgt ccggagaagc
    29341 agtaacatag cgccccgtgg atgaacacct cgataccgat gttggagctc tcggcgatct
    29401 ccttgacctg ttccaaaccc agttctcggg ccaggatgac cctttcgatc ccctgtttct
    29461 gagcccaact gaccccggcc gaagtatgga cggccatctg ggtggaggcg tgcaccggta
    29521 tagagaagcg ctccttgatc aacggcagaa ggccgcggtc ctggacgatc actgcgtccg
    29581 ctcccgcgtc gtccagcatc cctacgaagg acagagcgtc ggccatctcc ccttccttga
    29641 tgagagtgtt caccgtgacg taggtgcgca ttccgcggtc gtgagtgagc tttatcgccc
    29701 ctgccagcag ttcatccgaa aagttgctgg cgaagtgccg ggccccgaag ctcttgcccc
    29761 ccaagtaaac agcgtccgcc cctccggcga tggccgcctt gagcgcttcc tccgtcccga
    29821 ccggcgctag cagttccatg acctggaatc acctgcccgg atattaattc cctaggcgtg
    29881 tagcgtacaa ttagccgtca tatcgaacct cccctccgcc gttcgaccgt cagggaagag
    29941 aatggcgaag gtggtcatga tgccaaagag gggcgacgcc cggccggcga tgcgcccaaa
    30001 ccaggaagga tgtaaatttc aattgctagg gaggatgatc gagcttgatt gctctgtttg
    30061 tccgcatgcc gacgaggctc catcggaaag gtgcctggga gcgatccgtg actccctgaa
    30121 cgcgcaccgg gaggccaccg ggatcgtgat gagcggcgcg caggacgtgt gggtccgcga
    30181 gagcggtgtc aactcgcttc gaacactgat tgccgctgaa acggcctgga aaggactgcg
    30241 tgacatattg gcttccttgc cctgcccccg gccgatctct ccagagagga ttaatcgcta
    30301 cctggaccgc atacgggcag gttcgtccga tatgttctgt tcgggcgagg gtgccacttg
    30361 cccttcatgc ctggaaaggc agcgtgaggc gttggacgcc ttgcgttccg acggcaggag
    30421 ggccaagaag acgctcgccg cggaccgttt ccgcatcatc gaggtcccag gagggagcga
    30481 cagatgacga aaggtccgat ggaactttcc gacgctctgc ccgggctgcg ccgcagtcgc
    30541 atggtcaaac catcgctgtc cggttactgg atagaacgag aggctcctgc cggatggcag
    30601 cttgtggacc gcaaggaaat tccgggcggg accatcgaga tcgttgccga ccctatgggc
    30661 gtgcggcaaa gatactgcgt gcttccctgg gaacacaccg ccgatcgtga ttcctccagg
    30721 cttctggcga aggcggtggc caaggtccga tcggtccccc cggcatcgct gggaggagaa
    30781 gagtccgagc ttcgttctca cgttcgatcg ctggtccgtt ccctgaaccc tccggcaggt
    30841 atagagaatg aactgctgga cgcagtgatg cgcaacaccc tggggctcgg ggtgctggac
    30901 ataatcctcc gggacccccg ggtggaggac atctatgtgg acgccccgtg ccaggacacc
    30961 cgggcctatc tcaccctcaa ccaggcgggc ggaaggaata tcttcggaag gtgcgagacc
    31021 aacgtgatcg tttccgagaa ggagatggta gggttggtcg gccgcctgaa gtaccgctcc
    31081 gggcgcccgt tctcccgttc cagcccggtg ctggagacgg atatcgctga cgcgggcgtc
    31141 cgagctaccg ccctgtgccc gccgctaagc ccggacggcc ttgccctggc cctgcgaaga
    31201 cgttccgatg tcccttggac attactgcgt ctggcggagc gcggttcatt ggacgaggtg
    31261 gccgccggac ttctctcctt cctcatggac ggcagggcgt ccatattggt ctgcggtgcc
    31321 cgcggttccg gaaaatcgtc cctattgtcc gcccttcttt tcgagttccc cgtggaccag
    31381 aggatattgg tcatcgagga tacccgggag gtgccggtga aggccctgca atcgttaggt
    31441 ttcaaggtgc agtccatgct ggtggacccg tcgctgagcg gcgatcgaac gtcatcggcg
    31501 gaggaagcgc tgcgcgtctc tctgcgcctg ggggaatcgg ccatagtggt cggtgaggtt
    31561 cgcggtaggg aagccatgac cctctacgag agcatgcgaa ccggaaaggc cggttcgtcc
    31621 gtgctgggaa ccattcatgg cgacggggcc aaggaggtgc acgaccgggt agtgaacgag
    31681 ctggggatcc cggaggcctc cttcgcctcc accgacgtca tcgtgaccat gggcctggtc
    31741 cgtcccggcg gggggctcgg ccaggttcgc cgcataaccg aggtggccga ggtggtccgc
    31801 actccggaag gccttagctt cctccccatg ctcacctacg atggcagata tcacctcagc
    31861 gaacggcata tgccaattct ggccaggatc gcggccggat ggggaatgga ctaccaacag
    31921 ggattggaga acctgcgtcg caggatcgcc ttgcggggat cgcttttaga gatggggcgg
    31981 gaggacccgg cctacctttc accggcctat tcccttcaag ccaacgaata tctatggcag
    32041 ggcggaaagg agaccggcca ggagttcatc gatcacctga gggggcgttg accggaatgc
    32101 ttggaaccac gggcctgccc aagatcgctg gaacggtacc cgccggcttc gcaaagatat
    32161 tctcacccaa gctaaggccg gggatgcagg aatcgatgtc tcggagggag gaatcggtgg
    32221 aggacgtttc gctcgccgcc tacaacgcat tcctctggtc cctcctggtc ttcgttccag
    32281 cgatcgtcat cgtcctattg ttcatgccct accccctggt gatgatggcc gccggactgg
    32341 tcgtcgctcc cttcctgctc cccgccctta tcatcgctgg tccttccagc aggtacgccg
    32401 ccgaacagcg gtccttccta atagacaccc cggcggtcat cggggccatg ggcatgagca
    32461 tgagccggtc gccctccctg gaaagggcgg tggagatggg caccaggtcc ggtgacgggg
    32521 gattgcagaa ggccatcgcc tccgtggcct ggaaggcctt gaccggcgag gccgccgacc
    32581 tccggcgagg gctgtccgct tggacctccg ggctggataa gatgaacgac gggttgcggc
    32641 gggccttgca cctgataatg gccgccgagg agagcgaggg cgaaggtcgc gaacgactgc
    32701 tcgatagggc caactcgatc gcccttgaag gactgaagga ggtctgcgag cggtatatcg
    32761 gttccctttc gtttccagtg atgctggtgt tcgcctttgg agtgctggcc ccggtgatgc
    32821 tgttctccct gatcccttta ctgggaatgg agaacgggct ggtgggcggg gacctcaacc
    32881 tgggcatgct gggactggtc cttctgctcc tggtaccggc gttcaccctg ggatacatcc
    32941 gatccatgat ggcccgcaac cccctgcgcg gtccacgaag gaaattggac ctcgacaaga
    33001 gcaggttggc gatcgtgctg tcctcggtcc cggcggcatt tctggcctat gtcatcgccg
    33061 gttccatcct tgtttccgcc ctggccggac tgggagttct gttggccgcg ttgatcggcc
    33121 taggagcacc agagaagaag ggggagcagg acaccgaacg gtccttcgtc gatgccctct
    33181 accgcctggg gaacgccatg ctgggagggc aggacctgga gcgggcgttc gaagaggtcg
    33241 ccatgaccga tcatggcgag ttcaggctat gggggctgag gttggtacac gccacccgta
    33301 ccgaccgtgt ctctctggcc gaggccattc gagccgaccg ggagctagct tcaagatacc
    33361 cagccctgca ccagaactac ctgacggtca tggcctgcgc cgaggaggac catctgggag
    33421 ccggcaagct ggccgtgaac ttggcccaat cgcagggtga tgtcgcccgg gcccaggcca
    33481 aggtccggga gaacctcagg ccggtggtgg acatgatgag caccaccagc acgctcttcg
    33541 ctccagcgat aatcgggctt accggcggga tcatgggcct gatcggtggc ggaaccgttg
    33601 ccttgaccgc tctggcctcc atctacgtcg tcgagctggc gttcatcgtc aatcacttcc
    33661 tcggaggact ggacggctgg agctccaggc aaagggggat gagaagctat gggacgcggg
    33721 gggcgatcgc cctcggagtc tatctcacag cttcactatg cggtcagacg cttctcttcc
    33781 accttctctg accaatagaa gttcgaggtc agagagctgg tgaagctcca gggatagttt
    33841 ctcccccgcc tcgtaagagt tgaccgtgtc gatccttctc tgaacggcgt ccaggggaga
    33901 catttcgaga gagcgtatcc cgtcgtagaa gcgcgcgttc ggacgaccgc cctccttgac
    33961 cgccagattt ccctttccca gcgtacagcg ggaggagaac tgcactccgt caattaggca
    34021 cgatatcggc ggttcggtac cagtgaacag agtggcgtag aacttcccgg gaaaatactt
    34081 tctggcgacc aggcccatcc ggtatcccag cagtacgtag gctccgaggt gcccatggaa
    34141 atcggcaagc cttctgaggt cgtccggcag ttcggccatg cttatgcgtg aaccgttcag
    34201 gatataaaag attcccgttc ccgctcaatg ccttaataat caggaggcat agcaggagct
    34261 aatgaaggtc ccggtcgcca agcgatacat gctcatcatc ggagcggtcc tgtcggcaat
    34321 cctattggcc atgatcatcg ccccgctcac cattccagaa ggtacggtcg gcggactcga
    34381 tggaagcatc gggagcctgg accatgagga tgaccttgag ttcgtcccat ggccgcaacg
    34441 ggccgtctac ctcctgggcg atataaactg ccatcaacag gccgaccgtt ccttcgaact
    34501 gaacgataac cagatgccct tctgcgccag ggacctaggg ctgcttgccg gagcgatcgt
    34561 cggcctggcg gcgttcgttc tcctaggcag gaaggtggag tgggcctggt tattggtcct
    34621 cctggtcccg atggccgtgg atggggtggt gcaggcggtg accgattacg aatccagcaa
    34681 cgccttgcga tccatcaccg gcctactggc cggtatcgcc gccggttacg gggcggggat
    34741 gctaataaaa aatttcttcc aaggtccgga ggttgaaaat ggacctagcc agcagtgaac
    34801 tcgattaacg ttgaacgctg ggaaaacagt tatatataat attgatgatt ggacctacca
    34861 gtcattccat atcattcgtt tttacacggt cttggaggac ttgattcata tggacaacat
    34921 gaagactggt actaccacta taggtatagt caacgctgac ggagtggtcc tggcgaccga
    34981 gcacagagcc accatgggca acttcatcgc ccacaaggag acccaaaagg tcttcaagat
    35041 cgatgataac gtcggcctta ccaccgctgg tctggtcggc gacgcgcagg tcatggcccg
    35101 gtatctccgg gctgaggtgg agctctacaa gttgaagagg accgccccca tgtccgtaaa
    35161 ggccgctgcc accctgacct ccaacatcct gaggaggggc ggaggcgctt acggctacta
    35221 ttacgtcggt ctgatcgtcg gcggctacga caaggaaggc ggacacgtct attccttgga
    35281 cgccgccggt ggatcgatac ctgaccatta catcagcgtc ggttccggct ctccctacgc
    35341 ctacggcgtg ctggaggacc actacaagag ggacataacc ctggatgact ccatcaacct
    35401 ggccatccgc gctttgaacg cggccatgaa gagggattcc gccagcggcg acgggatgga
    35461 catagtcacc atcaccaagg acggctacat cgaggtgtct caggaagaga tcctgaagcg
    35521 cgcctctcgc atgggcatca acgttccccg accatactga aacccctttc caaacgcctt
    35581 ccctgttata attccagtaa gtgaaagtca tgagcgcaga aacaattctt gaggatgccc
    35641 gagagcaggt tcggaagatc gttccctcaa ccgtcgatat aacatccatc gatttcgaag
    35701 ggcccctagt ggtcatctac accaaggaca tggaggcctt cgcctccggg aacgacatgg
    35761 tccgccagat cgcccaaggc ctaagacgcc gagtggacgt gagaccggac cccaagaccc
    35821 tcaaggactc cgcggatgtg gagaagaggc tgcgggagat catccctgag gaagcacaga
    35881 tccagaacat ctatttcgag gatgataccg gagaggtcta cattgaggca ctggcgccgg
    35941 ggattgccat aggcaagcag ggcgcggtgc tcaacgagat caagaaggag atcggctggg
    36001 cccccaaggt cattcgagcg ccgcccatac agtccaagac ggtttacgag accagggcct
    36061 acctgcgaga aattcacgat gatcgtaagg atttcctcag aaaggtggga agacgcctgg
    36121 cgcagcccaa gaccgaaggt gacaactgga tacgcatgac ctgcctgggc gggtatctgg
    36181 aggtcggccg ttcggcgacg ttgctgcaca cccgggacag caagatcctg atagactgtg
    36241 gcatgtggcc ctccaaggcc gagccccagc cgaaacctta cttcaatgca cctgagttcc
    36301 tgcctttcga ccagctggac gcggtcgtca ttacgcacgc ccatctcgac cactgcggac
    36361 ttttacccac cctgttcaag tacggctacg atgggccggt gtactgcacg ccgccgacca
    36421 gggacctcat gtccatgagc ctgatcgacg ccatcaaggt ggcctatggc gaggccaagg
    36481 ggaacgagta cgaggcgaag catgtgcgcg aggtggtcaa gcactgcatc accctgaagt
    36541 acggagagac caccgacatc acccgcgata tccgtttgac gatgcagaac gccggccata
    36601 tcctcggctc ggccgtctgc cacttcaacg taggcgacgg cgcctacaat gtgacgttca
    36661 ccggcgacat gaagtacgag aggagctggc ttttcaacgc cacgaccaac aagttccccc
    36721 ggctggagac actggtcatc gagtccacct atggcggttc gaacgatata cagcccagca
    36781 gggtcgatgc ggccacgcaa ttgcgcggta tcatcgaaag ggcgatcatg gaacgcaagg
    36841 gaaagatagt catcccggtg ttcgccgtcg ggcgttccca ggaggtcatg ctggtgatag
    36901 aggaacttgc ccgcaccgga aaggtggaca aggtcccggt ctacctggac gggagcatct
    36961 gggaagctac cgccatccat accgcttatc ccgagtacct caacagccaa ctgcgcaccc
    37021 agatattcca gatggggcag aaccccttcc tgagcgacat gttcaagcgc gtcgattcgc
    37081 aggagatgcg cgataacatc ctgcatgacg tggagccttg catcgtgctg gccacgagcg
    37141 gcatgatgaa cggaggaccg gtcatggaat acgtgaaggc ctgggccagc gatcccaccg
    37201 cctccttggt gttcgtcgga taccaggcgg acggaacgat cggccgcaag atccagagag
    37261 gggtgaagga gctgaccttg ccagacaagg gaaagcagat caccgtggac ttcaagatga
    37321 acgtggaggt cgtggacggc ttctccggac actccgaccg ccggcagctg atcaactaca
    37381 tcgcgtcgct tgacccgaag ccggaacgaa tagtcatcgg gcacggggag gagaagaagt
    37441 gcatggacct ggcttccgcg ttgtaccgca agttcaacat aaccaccagg gcgccgatga
    37501 acctggagac catccgtttc aagtgaaatc cctttcccaa ccttctattt attaaaaaaa
    37561 taaggggagg gggttcgccc ctcgttatca gaacccgtat atcctggaca tcttccggtc
    37621 caggtacttg aggaacggcg tcacggagac gtcctttccg gtcaccacct tcaccaggtc
    37681 ggccgggtcg taaagatcgc ccttggagtg cacgttggtc ctgagccatc ccaacacggg
    37741 ggagaagtct ccgtttcgaa cgctcttgcg ccactgcgga acgtccttct gcatcttgtc
    37801 caggaacatg ccggaatata tgttgcctag cgcgtacgac gggaaatagc cgaacgaacc
    37861 gccggaccag tgggtgtcct gcagcacgcc ctcgccgtcg tgctctacct tgacgcctag
    37921 ataatcggaa tacttctggt tccacacctg cggcagctcg tccacggtca cctgatgcga
    37981 gaatatcatc ttctcgatct cgaatcggat gatcacgtgc agagcgtacg tgacctcgtc
    38041 ggcctcgatg cgcaccttgg acgggacgac cgcgttcgcc gcggagatga tgtcccggtt
    38101 cttcagcccc ttgaaagatc tcggggaata cttgcggaac ctcgggagag cgtagttcag
    38161 gaactccggc gaacgcccga tgatgttctc cacgaagcgc gattgcgatt cgtgaatgcc
    38221 gtaggagcac ggtgtgccga taggctggta catccattcc ctcgggatac cttggtcata
    38281 cagggcgtgg ccgccctcgt gcatcacgct gaagacgttg gagaagaagc ggtcctcgta
    38341 atagtgcgtg gtgatgcgga catcgtcaaa ggttccggtg gtaaaggggt gctccgtctc
    38401 gtccagtctg ccggcggcct tgtcactggt cgtatcgaag tgaatgaagt tcatcacgtc
    38461 cagggagatc ttcttctgca cctccaccgg cactttgcgg gacatggggg acatgtccgg
    38521 ccgatagtcg catgactcca ccttgccgat gagcttgatg agcccttggc gcagttcggc
    38581 gaagacctcg tcgatgcgcg cggcggtcat gttcggctcg aactggtcca ggagcgcgtc
    38641 gtacggcgtc ttcgttcctt tgaccttcat caaaatctcc gccgcctgct cgcgcaggtc
    38701 tatcatcttg gccaggtcgt cccggaacat cttgaagtcg tgggcggcct tggccttctt
    38761 ccagaccatg ttgcatttgg actggtgcat cgccgtttcc gtgaccagct tgtcggggat
    38821 cttggagttc tcgtcgtagc tcttgcgcag caggtgcagg ttcctgctct gccattgatc
    38881 gaagacgctg aggtcgctct cgcacctctt cagaagcgcg tcgttctccg ggtcggtcat
    38941 cttcttgtgc acgatgagct ccaaagctga gagctgctcg ccgcgcatgg cctgggcggc
    39001 cgggggcatc ttggtctcca tgtcccagta cagtatgctt cctgcggaac ccagcacgaa
    39061 catctccttg gaacgggaca tcaggttaga atatgcttcc ttcagatcgt tggtcattgg
    39121 tatcgggaag cggtatggca gggtgcgaat taacctttgc cgtgatacat gggaagaacg
    39181 gtatggcggc cttttcggtt cgttgttcca taagggatcc tcacaccttt tgaaatacct
    39241 ttaaaattgt gtaatcctca agcgttggaa cgcgacgcgc caaattcatc ttgggggtgc
    39301 aagctaaatg gaagaggtat ccaacaccgg ccttcctggc ctggacaaga tactcgagcg
    39361 tatccagctg ggggacaacg tggtcctgca ggtggattcc atcgatgatt acgtgaagtt
    39421 cgttacccct ttctgcaagg aagcggggag gcggggccgt cagctcatct acttccgctt
    39481 cgctgaccat cgcccggtcg tcccggagga cagcaaggcc gaggtccatc gcttggaacc
    39541 gatcgagggc ttcgagcaat tcatctccga aatactggac gtcatcgatc acaagggaaa
    39601 gggagcgttc tacgtcttcg attacctttc tgacctctcg gtcgattggt acagcgaccg
    39661 catgttgggc aacttcttca tgctggcctg tccctacctc tatgtctacg acaccgtggc
    39721 ctacttcgcc ctgatacgta atcatcacac ccctttcgcc atcgacgcca ttcatgggac
    39781 ggcgcaggtg gtcattgacg tgcacagcct gggggtgcgc acctatgtcc atccgctgaa
    39841 ggtggagggg cgccgctccc ccaccatgta catgctgcac caatgggacg gggacgaatt
    39901 cgtaccggtc ctgaacagct ccaccaccgc cgagatactc accggtgtgc cgcagccctg
    39961 gctcgactat tcgatgcata agcaggacat ctggaccagg agctttctca aggcccagga
    40021 gttcgtggag accaacgcgt tcgagcggac gacggaccag acctgcgaca tcctcttcct
    40081 gcgactggtg cggatggcgg tgaccaggga ccccagggtg atgaggctga tcgaaacgta
    40141 cctggacatc tcggacctgt tggacatcgg caaacggatg atcggaactg ggcttatcgg
    40201 gggaaagtca gtcggaatgc tgctgtcccg ggccatactg aagaagaacg accaggaatg
    40261 ggcgaagaga ctggagcctc atgactcatt ttacatcggt tccgatgtct attacaccta
    40321 cctcagccag aacggctgct ggtggatccg gcgcaaattg aacgatcccg cctccggctt
    40381 cctcttggac gaccatgaca aggaaagaat gctgacgggg aaattcccgg aggacatcgt
    40441 ggaccagttc aggaagatgc tggagtactt tggccaatcg ccgatcatcg tccgctcgtc
    40501 cagcctcctg gaggacgctt acggcaacgc cttctcggga aagtacgaaa gcgtgttcct
    40561 ggccaaccag gggacgccac aggaaaggct cgaccagttc ctggatgctg tgcgacgcgt
    40621 ttacaccagc acgctcaatc gggaagccct gacctatcgc gcccactggg gcctgctcga
    40681 gcgggacgag cagatggccg ttctggtcca gcgtgtgtcg ggctccgttc acggcgacac
    40741 gttctttccc caggtggcgg gagtagggat ctcctacaac ccatatgtct ggagcaagga
    40801 gatcgatccc cgtgccggca tgatgcgctt ggtgttcgga ctgggcacca gggcggtgga
    40861 ccgggtggac gatgattaca ccaggatcgt ggccatgaac gcgcctctgc gccgaccgga
    40921 gggcagctcg caggacgttg gcaagtattc ccagagaagg tgcgacgtga tagacctgaa
    40981 ggccaaccgc ctaacgtcgt tgccgttcga ggacctcgtc cggaactccc cggacatccc
    41041 tttggacatc ttcgcctccc gagaccgaga gctggaaagg agggtacagg agtacggtgg
    41101 gaacgaggcg ttctcatgga tcctgacctt tgaccgattg ctctccgaag gaacgttcct
    41161 ggacgatgtg agaaggatgt tccgggtcct ggatggcgct tacgatcatc ccgtggacat
    41221 agagttcact gcgaacttcc gagacctggg ggattaccgc atcaacctcc tgcaatgccg
    41281 gccattccag gccaagggtg acgctctttc gctggcggaa ccgtgctcca ttccttccgc
    41341 ccgcaccatt ctggcctcgg aaggtcacgt cataggaagc agcagggcgg tgaccgtgga
    41401 ccggatgatc tacgtcgtcc cggagaccta tggcaaaatg aggatgagcg aacggtacgc
    41461 cgtggcaagg cttgtgggca ggttgacgca cctgaaggat ttgggcgagc acccgactct
    41521 gctcttggcc gggccgggaa ggtgggcgac cacctccccg gagatgggag ttccggtctc
    41581 cttctcggag atcaataccg tgtccatcct atgcgagatc atttccatgc acgagggcct
    41641 ggtgcctgaa gcgtccttgg ggacgcactt cttcaacgac ctggtggagc tggatatgtt
    41701 atattgcgcc gtttatccag gaagggatgg gcatgtggtg agcggcgagc tgttcgacaa
    41761 ggccgagaac cggctttcgt cgcttctgcc cgattcagcg ggcctatccc atgtgatcaa
    41821 ggtcatcgac gcggacggcc tcggcatccg ggtctgctcg gacgtgagga aacagacctt
    41881 cacatgctac caggaccgca aggacgttcc ctgagggcgc ccgtatctta ccacagggaa
    41941 gagggccaaa tgccgttcga agagcgtgtc aaccgtgata tacgggctct gagttcctgg
    42001 gtgatggtct ttgaccggga cccttaacgg gggagagtgg tccggaacat gagcgcttcg
    42061 aaaagagcgg atgagcttag aacgttcctt gacgagagga tcgtgcaacg actagcatca
    42121 tccgtgagca ggatggacgc gcggcagaag gtcctgtcgc tccttctgat caccttgttg
    42181 atctatggcc cagcgatcgc ttactatctt tccgatccat ccgtacaata cgattttgac
    42241 atctacaggt cccggacgca gaccataatc gacggaggat gcctctatcg tgacgttcac
    42301 acggagaccc ctcctctcat caactatatc atggtgcccg cccagctcct gggaggagcc
    42361 gagagcgcct atgtgtgggg tgcgtacgaa gcgttcttcg ccttcctcct ggccgtgatg
    42421 ctctatctgt cgttccggaa gttcgatgag atgaaggcct tcggaatggg tgtgctgacc
    42481 atcctgtcgc cttacctgat aatcgaatct gccaccgggg aggatgcggc catcgtggcc
    42541 ttcgtgttct tcctgggcgc ggtgctgatg gtgctggaca agaggtatgc ggtcctggcc
    42601 atcgccttag gcgcctggac caagatgtgg ccggtgctca tgatgccggt ggagttcctc
    42661 cggtccagag gtttcaagaa gaagaccgag gtcattctgc tggcggcctt gatcaccgtt
    42721 gcgatcaccg ctccattcct gttcctgtgc tccgacaagt tcctggagtt catctccttc
    42781 tacttcattg gggacccctc gcgaccatcc ggaggaagaa gcctctggaa cttcctgcgc
    42841 gacggcggat atggattgcc ggccatcgta gagctggccc tggtcatcgg ctcgctgctg
    42901 atcgcctacc tatacagcca tttcaagaac tggggtgcct ggaggtccgt gaccctggcc
    42961 atgctcgtct tcattgtgtt ctatccgaag atgcatatgg gttactacgt catgcccttc
    43021 gtgctgctgg ctgcctggtc ggtcagtgac tggaagatag ccgcccggtt gttcttggcc
    43081 tacataccga taacctattc cggcggtttc gcctccgaca accctgatcc gatattcgcc
    43141 accgctgacg gtggatggat cataggcctg cttctggttc tctttgccct ggtcctgata
    43201 tgcgacgcag ccaggatggc cttcagatcc cctgccttcc tggagaccgt ccagatctcc
    43261 ggcgggcaga ccgaacttac atgatcatcg ttctggctag agcaaggatc attttttgtg
    43321 taagggcctc ttacgctcgt ctaagtgagt tggatcatta gccg
//
LOCUS       DAOPZI010000010        42451 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_777_length_42451_cov_10.281866, whole genome shotgun sequence.
ACCESSION   DAOPZI010000010 DAOPZI010000000
VERSION     DAOPZI010000010.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 42451)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 42451)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42451
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_777_length_42451_cov_10.281866"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..601)
                     /locus_tag="PKM11_03345"
     CDS             complement(<1..601)
                     /locus_tag="PKM11_03345"
                     /inference="COORDINATES: protein motif:HMM:NF012464.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HNX47573.1"
                     /translation="MKVALYARVSTDDKEQNPETQLLILREYCEIYEHQVVATFVDEG
                     RSGKDPARPAFKDMMKEATNRSKRRFQAIICLRLDRFMRSALYGLQATQQLQDVGCGL
                     IFVKDQIDTTTPGGRFFYTLMLAFAQMEREHHGERVSEGIHRRLKEGGSWGKGRRKDV
                     NVGLAVELLRSGNARSISDAARQLKVPSSTLVDHAKKKGI"
     gene            complement(598..894)
                     /locus_tag="PKM11_03350"
     CDS             complement(598..894)
                     /locus_tag="PKM11_03350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47574.1"
                     /translation="MAKFENVYRIIGPELDELARLNKGQIPRAVFERLIAENFGCNDR
                     TISSYTRTFKTFGIIRPLNKTWYQFKPWTHGGEDEEDETLSHQLAKVAPMDREP"
     gene            complement(1469..1630)
                     /locus_tag="PKM11_03355"
     CDS             complement(1469..1630)
                     /locus_tag="PKM11_03355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47575.1"
                     /translation="MGPVGYTVSAPIWLTADFQRKLERFKINRVQQLADAEVLIAKAF
                     YGESMGERP"
     gene            complement(1919..2074)
                     /locus_tag="PKM11_03360"
     CDS             complement(1919..2074)
                     /locus_tag="PKM11_03360"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47576.1"
                     /translation="MNRCEKWSVCPLGNLADTVGCRKPHCPKANMPHRSGLFTKDMVI
                     PVKKSKE"
     gene            2184..2618
                     /locus_tag="PKM11_03365"
     CDS             2184..2618
                     /locus_tag="PKM11_03365"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR00369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - acyl-CoA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HNX47577.1"
                     /translation="MSEWESFLPKYVCERLQSMMDVQFVVDLGIETRSITKDGEVRCV
                     MNVSDKLNAYGGGHGGAVFALADQAFALASNMGKEKQVAMVASINYIKPGTGVLEAVA
                     RRTSETKKTSLYEVKVFDDGKLVAVFQGTGYKIGEKRPTASR"
     gene            2699..3187
                     /locus_tag="PKM11_03370"
     CDS             2699..3187
                     /locus_tag="PKM11_03370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47578.1"
                     /translation="MGIVVKVEIYHASKYGNGEKVVAYLQGLLVAKGHQADYRHIRDA
                     RPKDMPAADLYVFCAPTRIGKPIGKMRRFLKKARLPEGAKYALIATHGEPVPDKKTGE
                     MPAPEVIEKYQQNLPAMEAILKDKGAVKVAEVKVYVQNTMKGPLSDGWEKVVEGFASK
                     LL"
     gene            complement(3216..7913)
                     /locus_tag="PKM11_03375"
     CDS             complement(3216..7913)
                     /locus_tag="PKM11_03375"
                     /inference="COORDINATES: protein motif:HMM:NF012271.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HNX47579.1"
                     /translation="MIVRGGVSFLSRRASAILLAVLMVMSTTVIVAVPQGVEAAPAGV
                     FQTEGGWGVEVVDAKGIVGIQSSLAIDDFGYAHIAYRNDEDGTLKYATNAEGFWNITT
                     VDTEVSTDLYSEISLTLDSKNEVHISYMSYYNSEDEFLIYATNAGGSWSKTVVDKHYR
                     AGCYNDIFVDGSDRVHIAYSVENALSDTDLKYANNTAGAWVNETADSGVEVGMYPSIV
                     VDDYGIIHIVYFDQFNVALKWAQKYPSGWSRSYLDDSGECGYFTSMDISGGTDLHVSY
                     FDGAGHLKYQHFDGVQWDLSITTVDSTAIVGEHSSICVDRDGAPSIAYYDSTNSNLKV
                     ARFLDGGWNCTTVDDAGASTVGEYCSIAIGPNGKIGVSNYFGGSDDLLYTSQNVWTFE
                     ELAGTTGNMCFGNTDIALSDDNNAYISYTANAGYELWLANNFWGSWTYTMVDNTTGDY
                     GGTTSIDLGSNNQVHIAYYAADSGEIRYATKATGNPWVKEKVADTKPNWSTNDLSMQV
                     DSDGKVHIAYSYFEDSGFTATLKYANNVGGTWVNETVDSSSADIGRYPSLALDASNKV
                     HISYRDQTNKVLRYATNAGGSWVLSPIDSSANVGEHTSIAVDRNGRPHVSYMDSANKD
                     LKYAFESGGVWVPTVVDSIGWVGEYSSIGLDLDGKAHISYYDNTNQDLKYATNAGGSW
                     AVSVLDHDGMVGSESGLAIGTDGKVHISYDDASNSQVGYATNSPWDFSTIYRMTGEAA
                     PENYLSMVRDDIGAYHIAFYDTHDTALRYATNRGGVASVTLVDNADDVGQYCSIAVDA
                     NGKAHISYYNATGGDLKYAVDTGSGWAKTVVDSTGDVGMFTSIALDVNGKAHISYRNS
                     SGDPRLKYATNAGGSWATVTVDTTAFSGTQTDIAVDANGKAFISYYTGLVGLKLANNT
                     AGSWAITNVDTGAVFKGQNPSLALGGDGAAHISYYDTSSHYLKYAMVKGASVTKRDVD
                     ISGNAGSRSSIDVDKAGKAHITYHDQLNGDLRYAVDIGGSWWTTTVDRNGLVGEINAL
                     DINDQGVLSVCYIDWTNNRIMLANQKAAPTAPRGLTLVADGLDVQASWSAPVSSNGPP
                     VLGYIVLHSYPSGEVERIIGLSDLSRTDTNLALGVHRYAIAAYNVLGTGPFCAEQQVT
                     IVPQTPPTAPTGLSATPGSGSVSLIWNSPVDSGGSPIQGFKVYRGTSSGTETLLTFVN
                     SSMNYLDLTVTNGVTYYYKVSAFNGYGEGPLSTEVSATPTLSLSVPEAPTNVVTYAHD
                     SRIELVWQAPLSDGGSPITNYKVYRGEASGALVLWSTLGNVLTYQDYSAENGIMYYYA
                     ISAVNGVGEGPRSNTVSVLLGSVPSVPMNLGASADGTSIVLSWDPPENDGGWNVSGYK
                     VYRGTSATNLTLLAALGNVVNYTDYEVVAGTEYYYAVSALNAKGEGARSNAIMMSTSS
                     VPSAPNNLEAEAGDAKVTLSWDAPTDDGGSPITGYVIYRGTSEGAVSTVLVTLGNVNT
                     YTDDDVVNGQTYWYKISAVNSIGQGTTTDAVDATPSADAGDSGDNTMLYIIIAIVIVA
                     AIAGAAVLFLRKK"
     gene            complement(8060..8629)
                     /locus_tag="PKM11_03380"
     CDS             complement(8060..8629)
                     /locus_tag="PKM11_03380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HNX47580.1"
                     /translation="MGEEVLLFSVSDVHEATDQSALGGTYVYRVAAVNAVGVGMKSQP
                     VEVTVEAVAYVPGVPRNLDADAGNGTVNPTWDQPNDNGGSPITGYIIYRGTSESNIVL
                     LLERGNATHFLDDSVMNGVTYYYKVSAVNGAGEGNLTGSVHATPTVEGGIDDDDDEGG
                     ENTMLYIIIAIVAVAAVAGVAFFILRKRK"
     gene            8852..10561
                     /gene="acsA"
                     /locus_tag="PKM11_03385"
     CDS             8852..10561
                     /gene="acsA"
                     /locus_tag="PKM11_03385"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HNX47581.1"
                     /translation="MAEEIPPTGTGNLRDYEEAYRSFNWASLHDEFDWSRGGPYNVAA
                     EAVDRHARERPEKVAIHSVRANGEVQSLTFRDISRSSSRFADGLRHLGVKRGDRVFVY
                     LDRRSELFISIIGITKLGAIACPLFSALGPEAVKDRLMDGTPSAVVTSPYLFDRISKV
                     LKDVSQMPLVVCVGDNSPPNTISYSQLLASGSPDFKTVDMRPDEPYIIHYTSGSTGKP
                     KGVVLPHRAMVQQLSGARYVSDLRDDDVFWCTADPGWVTGTSMGIFGPWYLGTTIISF
                     EGRFDARSWYSLVDRFKVTVWFTAPTALRMLMKAGDEVVREFDLSSLRHMCSAGEPLN
                     PHVVRWGMEVLKRRIHDNWWQTETGAPCISNFRCMTVRPGSMGKAVPGMVAAIVDENG
                     MELPHGKEGFLALRPGWPSMMTGIWGNVTKYREYFYVPGWYASGDQAFKDEEGYIWFL
                     GRADDVIKTSGERLGPFEVESALIEHPSVAESAVVGKPDELRGEIVKAFIVLRPGNDP
                     SEGLRQDITNFVRVRLAYYAYPREIEFVDSLPKTRSGKIMRRVLKAKEGGHETGDLSM
                     LDD"
     gene            10635..11264
                     /locus_tag="PKM11_03390"
     CDS             10635..11264
                     /locus_tag="PKM11_03390"
                     /inference="COORDINATES: protein motif:HMM:NF017959.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HNX47582.1"
                     /translation="MGLLDKDPCWSRRTAGALIMVAAFIVLMGIITGEAMYPGYHTGD
                     NDISDLALEEPSATIFNSTMIVGGIMFSLTAILLRHAGLPRSVTVPAFLMGLGGAGVG
                     LFPVYTGSPHYVAALMTFSMGAVTALMAGRTADAPFKYISLALGTIGLISLVVFAMMW
                     GGEPIGPLGEGGMERWVAYANMVWAIGFGGYLMNSGPDRSRSKMSCNRP"
     assembly_gap    11363..11462
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            11640..12074
                     /locus_tag="PKM11_03395"
     CDS             11640..12074
                     /locus_tag="PKM11_03395"
                     /inference="COORDINATES: protein motif:HMM:NF018621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1284 domain-containing protein"
                     /protein_id="HNX47583.1"
                     /translation="MKELRIRHHHLLCTSTFVGHGYDGRFVTNMEKVVSILRSPEELV
                     IHLDIRCDDLCSSCPHAVRGVCKDHTSVVGKDRSAARFLSLPEEGSFPAGPLLDMVKK
                     RLRALDDIHLVCGECEWADLCNARLSTLRATASAQDRPVKKL"
     gene            12099..13865
                     /locus_tag="PKM11_03400"
     CDS             12099..13865
                     /locus_tag="PKM11_03400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX47584.1"
                     /translation="MDAELRIVMDMTLLMVISGLCSLLFARIKMPPILGYLTAGIILG
                     PTMFPDLWVEQTTVMVLSNIGIVMLMFWIGLEQSASKLKRVGSRLIMIVTLEMTLVVI
                     IGYLGGMALGLGSTASIFLGAIISGTSTAVVVGVLQSVKTIDGEQATAIMSITVFEDV
                     GQVIILSLAAPLLAGDSPALGSTINMVIGLIVFFGLSIMIGLALIPRIMDRIGDRYPS
                     EMVFIVAVGMVFAMALLSSSVGLSIAIGPFLMGLIVSMSLYSERIKAKVIPVKELFMA
                     VFFISIGLQMDPRMVIDNLPLVVSIAALFIFGKMFVLIISTYIFGYKAKDSFVISISL
                     LAMGEFAFIISKIALDAGLLSQELYSSVIGAALITMVTLPLTSKFQGPIYSAIVRITP
                     VKLRSAFGRMDSVKEAATSRNVMMSDDRRKLSGHLTRIFIDYLYIVLVMLVFNLVSEV
                     NTVIADAAGDLGVLPGAALLFIMLLVISPAVVSVYRNLKKVSAALTEMAMRSQRIAEG
                     NRRNVYRMFFDLSEIVMFLLVLALIIPFVPSGLVTTPLLFGFIAIVVAVVVILAWDAL
                     RNSYVRFLGMVTGNGAKDGPEE"
     gene            complement(13895..14185)
                     /locus_tag="PKM11_03405"
     CDS             complement(13895..14185)
                     /locus_tag="PKM11_03405"
                     /inference="COORDINATES: protein motif:HMM:NF020317.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GYD domain-containing protein"
                     /protein_id="HNX47585.1"
                     /translation="MGVYVVMSKLTQEGRKTLKSRPERLKEVNKEITKMGAKVIQQYA
                     LLGKYDFINILEAPNNETVVKIMVALGSRGTLETVTMAAIPVDDLLKAIKEE"
     gene            complement(14238..15476)
                     /locus_tag="PKM11_03410"
     CDS             complement(14238..15476)
                     /locus_tag="PKM11_03410"
                     /inference="COORDINATES: protein motif:HMM:NF019310.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47586.1"
                     /translation="MSVRSKFSDRKGTKVPAQVKWLILLTSFSSIGYGYLTTAIAAYL
                     PEQGVDSGQVGLIIGLSGLAMIISAIPFGLMSDRLGRKRLLLAGLALLPFSMFICSFS
                     ADPRLYLAAAIISGVAEGAILSTWNAMIADQTNVDNREMAFSMSFIVNGAFVGLGFAL
                     PFAFPAIMDLGGWTSQQVHSWAFVFIGLVTLISPVTVHFLLKNYHDTTPSAKLRRGSF
                     LKERSKKTLVRFSVNNTLIGLGAGLIIPLIPTWFYLRYGIPDSYSGPLLALSSLSIAA
                     AAIFSPRIAHRYGQVPAIVMTQGFSTIFMLAIPFMPGAIWAGAIYLVRSATMNMAGPI
                     MDSYLMGIVDKEDRGLASAINSIVWRVPNSVTTVIGGAMLAAGYFALPFVLAALIYIA
                     AVTAFWFNFRNVKVHEEPSA"
     gene            15606..16325
                     /locus_tag="PKM11_03415"
     CDS             15606..16325
                     /locus_tag="PKM11_03415"
                     /inference="COORDINATES: protein motif:HMM:NF013936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HNX47587.1"
                     /translation="MLPIAPLMIEHRLIESMAAVMNEQAEGLQAGQELDPRFIPEAVD
                     FMRTYADRTHHGKEEDILFKVLRGKKLSGEHRQVLERLEADHVKAREMVARLSALGDE
                     YLKGSPSAAYQAALLMKDLVGFYRAHIELEDQGFFVPVMEYLSADERQAMLEEFRDFD
                     SRMVHERYAKTVQRLGGGSSVHLARDDGDRWRCRVCGYVYDPRDGDPENGVPAGTSFA
                     DLPDDWVCPVCGAGKDAFEHL"
     gene            16365..17105
                     /locus_tag="PKM11_03420"
     CDS             16365..17105
                     /locus_tag="PKM11_03420"
                     /inference="COORDINATES: protein motif:HMM:NF013077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HNX47588.1"
                     /translation="MSEEPGQDFQRETKHRRDRLVGRYMDFDRRPETYKEYPERPRTI
                     LPEPQRPASSLDNLLRTRRSVRRFSKDPVSLDELSYLLWASDGISKKAGVHELRTAPS
                     AGALYPVETYVAVNDIPGLAPGIYHYSVKHHALELVRKGRLGEELARAALDQGMCASA
                     PAVLMWTAVFERCRWKYGERAYRYVYLDAGHIAQNLALAAVSLGLGSCQIAATFDDEV
                     NELLGVDGEEESVLYMSVIGRPANSAND"
     gene            18159..18605
                     /locus_tag="PKM11_03425"
     CDS             18159..18605
                     /locus_tag="PKM11_03425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47589.1"
                     /translation="MGPPPGGMMLMPQVAAAAMLRPNERTAQVWRAGLEQDYVAGDDD
                     ESGTFNVSGVLIATDQRLIFVQEKGVFGKSYKPLESMEYREIVNWKLGQTMRIKSLQV
                     DVSQGRHRRKVFNNLSEVDPMTLSVIAPWTLDQVKQLLGNLKSAAP"
     gene            complement(18612..19424)
                     /locus_tag="PKM11_03430"
     CDS             complement(18612..19424)
                     /locus_tag="PKM11_03430"
                     /inference="COORDINATES: protein motif:HMM:NF026098.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase dimerization
                     domain-containing protein"
                     /protein_id="HNX47590.1"
                     /translation="MKIGFIGLGNMGSSLAAGLLDSGAISPENTVVANRGPSKAVSFA
                     GRFPGVSVAESNVKAAKGSDVLFVAVRSDQLLGVLREVSSAGPYAHVVVVNGSLPLAV
                     LEGVCKTPMSKLIPSVTMERGRGVSLVSHGPSVTRSQASSLEKVLARASKVRVVQEDG
                     LDVATDLTSCGPALLAEMMHQFAEAGVRQGMDRKEAWDMVLETMQGTALALGSGESVA
                     SLKEKVATKGGITEQGLLVLEDVLPAIFDLVFARTMAKQAEVRKRLLKDVGP"
     gene            complement(19479..20027)
                     /locus_tag="PKM11_03435"
     CDS             complement(19479..20027)
                     /locus_tag="PKM11_03435"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HNX47591.1"
                     /translation="MDRAEALELVRGHVSKESNLKHMVAVGAVMRQAAVHLGEDLELW
                     EVTGILHDIDFEECHGMQDHALIARDILQGKVPNEVVQAILAHNHEATGVPVDDRLKR
                     GLLAADAVSGLVIACALVLPSKKLADVKVSSIAKKFGNRDFARGVDRDRIMVCERLSI
                     PRDEFLSVALEGMKLRSDELGL"
     gene            complement(20069..20473)
                     /locus_tag="PKM11_03440"
     CDS             complement(20069..20473)
                     /locus_tag="PKM11_03440"
                     /EC_number="1.-.-.-"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: protein motif:HMM:NF013412.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine-phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HNX47592.1"
                     /translation="MVKMPTEVKEALAKQKPIPIATATRDGTPNVVFVGLMKIIDDES
                     LLLVDNFFLKTAANLSENPRISILCYDTDTKKSYQIKGSAKVYKAGPMFDEMRKWVQG
                     VNPKLPAKAAVVVKVEAVYDAMWGPSAGRLIV"
     gene            20590..21120
                     /locus_tag="PKM11_03445"
     CDS             20590..21120
                     /locus_tag="PKM11_03445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2148 domain-containing protein"
                     /protein_id="HNX47593.1"
                     /translation="MSNKEAVIMVGRLMELAARTAPKAMGKDLIETALLTDEQRVKLG
                     EDLIAVGKERGLPGYQRDGQNVLDSDAVVLIGLLPHLGVGLDCGACGVSGCAEFNVLS
                     ASKDFQGPNCALRLLDMGIALGSAAKVASDHNVDNRIMYRIGVSAIRLGYSRSNICHG
                     IPLSVTGKNIFFDRGK"
     gene            complement(21121..21687)
                     /locus_tag="PKM11_03450"
     CDS             complement(21121..21687)
                     /locus_tag="PKM11_03450"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HNX47594.1"
                     /translation="MTKRTLGRTLPMMGLPVVVVGAKVQGKVNFCTIAWATMIDDEPP
                     KMAVVMGKDRRTKDGIRENRTFSINLPDVGTAAAADHCGLVSGYQEDKSNVFDVFFGK
                     TLTAPMARECPVNIELILDEIIELEGTDIVIGEVEEVYVDESRLTGGVPDMDKLQLLM
                     YLSSGGLYFTKGKTVAEAFKVGKDFRPK"
     gene            21835..22467
                     /locus_tag="PKM11_03455"
     CDS             21835..22467
                     /locus_tag="PKM11_03455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47595.1"
                     /translation="MAEAKKQDLPFAADALHTTALATPFIVAFNEGEAGYYGLSHEIQ
                     RIGRSCLTPGARVVDLRCDLNLVMPIIEENEDLCRFTLLSPDERSGFRCFDKLRTRVR
                     LGFVDAAQLDLNEGFPEVSARMVLAIGALGGLSERRRTEVADSMHRRMERNGVGVIME
                     VVETDVAPGLRRKRPLWSAAEWESLFKNAGFRSVQRLWTDGERMAWTVKK"
     gene            complement(22511..23197)
                     /gene="aqpZ"
                     /locus_tag="PKM11_03460"
     CDS             complement(22511..23197)
                     /gene="aqpZ"
                     /locus_tag="PKM11_03460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015250 - water channel activity [Evidence
                     IEA];
                     GO_process: GO:0006833 - water transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HNX47596.1"
                     /translation="MDKSVMKKLVAEMIGTFVLVFGGVGTAVLAGSWVGALGVALAFG
                     FTLLVMAYAIGPISGCHINPAVTLGMFMSKKIGGKEALFYMVAQVIGAILAAGILFIV
                     ASGGPGFDAAASGFGSNGYGDHSPGGFELGAVMIIEVVLTALLMLTVLFTTDKKAAAG
                     FAGIPIGIVLALIHLISIPVDNTSVNPARSIGPALFQGGWAIEQLWIFIAAPMVGAAL
                     AAIIYDLLKD"
     gene            complement(23300..24082)
                     /locus_tag="PKM11_03465"
     CDS             complement(23300..24082)
                     /locus_tag="PKM11_03465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47597.1"
                     /translation="MRIMEWNLQYGGAQERLPGIVEAVRRHDPDILVLLEFRPERIIE
                     VSLSLAALGYPYILNSQPPPRTNGILVASKSALVQLPGGRTLSSPHRWMEVSPEGSDL
                     RILAVHVPGASDLPGKMEFWQALLEFAKESVDLKDRRMIIGDLSTGLERDSEGTPFLG
                     TEHLSALLDLGWRDVWREYHQVAREYSWYSSSGKGMRTDHGLASPQIQHPLWAKYSHQ
                     ERVSGISDHSILILDIMHRLNDTGSRSSPLFRMGEGPGCTIG"
     gene            24369..>24549
                     /locus_tag="PKM11_03470"
     CDS             24369..>24549
                     /locus_tag="PKM11_03470"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HNX47598.1"
                     /translation="MVKGHSASSFRFRLNNGVEVPALGLGTYKLPGEQAYAPVRMALD
                     CGYRHIDTASFYENEE"
     assembly_gap    24550..24649
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <24650..25051
                     /locus_tag="PKM11_03475"
     CDS             <24650..25051
                     /locus_tag="PKM11_03475"
                     /inference="COORDINATES: protein motif:HMM:NF012472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HNX47599.1"
                     /translation="FTVRHLQELYSACQVMPAVNQVEMSPFLFQKDLLEHCQVRDILV
                     TAYSPLGRGQVLADPVLKEVGDRHRKTPAQIILRWCLQKGMATIPRSADIGHIQQNSQ
                     IFNFDLDGEDMARLDLLHSGLRTTTDPDTFE"
     gene            25094..26281
                     /locus_tag="PKM11_03480"
     CDS             25094..26281
                     /locus_tag="PKM11_03480"
                     /inference="COORDINATES: protein motif:HMM:NF014045.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HNX47600.1"
                     /translation="MTEQVPKIAIYLDFENLAISAKEVYPSTPRPLRIDDILDYAKGY
                     GDVLIKKAFADWNKPPCNQYVEDLRLRAFDLIFLPQTSLSGKNGADLRMTIDALEDMY
                     DKDLLDVFFLGTGDTDFIHLVRKLKERGKEVVVLGFEHSVGRTIRYNCDRFESLEDLL
                     GKPPAPAAKEKKEEEELEDDPRELFIRYVKNRSTDEPAILSQIKNDLMRLDPSFSEKK
                     YGYKHFKDFLETFRGDLFTNIKMDDKAGHHLVFFKSYSELTSDINEAQVRDFIEKDMR
                     FLKDRNLRKALYKEIVNLFHADGETTINQMIDDLWSLFDKKVPKATLKRFLRTMAEGR
                     MFKFAAVKYTGNIYTMPQVLKADLPSMEKLDDIYVQRIIDLTLKKYSGVPQETVTKLM
                     GLS"
     gene            complement(26356..26880)
                     /locus_tag="PKM11_03485"
     CDS             complement(26356..26880)
                     /locus_tag="PKM11_03485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47601.1"
                     /translation="MPGASRKVEIVRVTPESADQLIALITELAVFEKLDPPTAEARER
                     LLQHVTSDPALFHAFLGYFDGRAVGYITYYFTYSTFLATPTLFLEDIYVQESARQSGV
                     GRELFKFCVQEAIDRGCGRMEWCALNWNVGAMRFYEKQGGRKMDWTFFRLDREGMTAA
                     LLKGQRSSNGDSST"
     gene            26974..27243
                     /locus_tag="PKM11_03490"
     CDS             26974..27243
                     /locus_tag="PKM11_03490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HgcAB-associated protein"
                     /protein_id="HNX47602.1"
                     /translation="MPRRRDSPKEECCTGPTEPPKYDVEGVATVDERGQMVLPKAIRD
                     KAGIRPGDKLAIVTLVRDGRVCCIHLFRTDDLANGVKDILEPREG"
     gene            27247..28227
                     /gene="hgcA"
                     /locus_tag="PKM11_03495"
     CDS             27247..28227
                     /gene="hgcA"
                     /locus_tag="PKM11_03495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042192 - methylmercury biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury methylation corrinoid protein HgcA"
                     /protein_id="HNX47603.1"
                     /translation="MEEGYAKETLTTVPQLGSKERNDHLKARIGLDRMGHRVRPGLYA
                     IGAPERTSPVLVTANYTLSFDALRSSLTGRSVWILVLDTKGINVWCAAGKRTFGTEEL
                     VKAVQATGLASKVEGRTLILPQLGAPGVSAHAVKKDCGFKVEYGPVRAEDLPAYLDTG
                     ECTEEMRTVRFTLKDRLVLAPVEIRNYRWWMLLMILAAVFVPFYGPLVLAMTLGGIFL
                     FPALLPYLPGKDLSLKGIVLGVLLVTPFALYQLLFWHGTFVFAAVVAEYLLIAAWLGY
                     LGLNFTGSTTFTSRTGVRREIFTYILPMAVMAILGGIAVVSSLVLYAGWL"
     gene            28227..28538
                     /gene="hgcB"
                     /locus_tag="PKM11_03500"
     CDS             28227..28538
                     /gene="hgcB"
                     /locus_tag="PKM11_03500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042192 - methylmercury biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury methylation ferredoxin HgcB"
                     /protein_id="HNX47604.1"
                     /translation="MEIGMLDLQPPEKGKALNTLVFHPGRCINCGMCLKVCPHRVFAP
                     GERRVRLVKAEACMECGACQMNCPAEAIKVDSGVGCAAAMIRAALKGKDGEECGEECC
                     R"
     gene            complement(28543..30219)
                     /locus_tag="PKM11_03505"
     CDS             complement(28543..30219)
                     /locus_tag="PKM11_03505"
                     /inference="COORDINATES: protein motif:HMM:NF028237.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal 7TM
                     domain-containing protein"
                     /protein_id="HNX47605.1"
                     /translation="MEYYGAIVIVPNLLAAAFTAGVAYKVLKGKETEHRTAMAICFAF
                     VSLNFMVLLAEKLIGDLDLVLAVVVLEYLCGSMIIISLLIFVIQYIGLGRYITRRNLL
                     LIAFPAILSVLLNSTNGLHHLFYRDVIIIQSHGFYMFEAEYGPLFVIWMGYMISVILI
                     TNILLARAFLETLPERRAGLGIIMLATLTILFSGLLYVFSPRDDPLIDILSIGYTLAA
                     LIVFVGERRSDFVNLEIIRFREAIGGMDDAVIILDSSLQVVYANKQGQKVLDQNSDYL
                     WGRMKARGLKVPAGSNKWETAMIIDGNARHFVLTTSDIFREGKPVGAVLVLHDITNRK
                     ALEEDLRRANRSMSTLNQILRHDIRNDLTASWGYLGLLEGTELNERQRHLMEKIMERA
                     RSANDHLDFASAQSSLGMSATAWQEVHSTVNKVLGKVDMDGIAVESRVEGIRLLADPL
                     LENVFHTLADNTVRHGERVTKVVVRGENTETGLSIIWEDDGIGVPADKKEMIFDKGYG
                     ENTGLGLYLAREILATTGFTIAEGGEPGKGARFVIKVPSGWFTWKWPLAQ"
     gene            complement(30304..31581)
                     /locus_tag="PKM11_03510"
     CDS             complement(30304..31581)
                     /locus_tag="PKM11_03510"
                     /inference="COORDINATES: protein motif:HMM:NF017760.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47606.1"
                     /translation="MMRTSGEGNSWKRSFFTIWGGQSFSLVGSALVQFALVWWLTVET
                     GSATVLALGTLMGVLPQVLVAPWAGAYVDRWNRRRTMIAADSLISLMALLLMLAFLAG
                     TAEVWMVLLAMFGRATVSGFHWPAMQAATSLMVPERHLGRVGGLNQAMFGLSSVIAAP
                     AGAVMIALFPMWAVLSVDLITAVIAIVPLMFIHVPEPDRGVKEKASLMNEMKEGLAFL
                     KSWRGALSIMFLFMIANLLLSPAFSLLPLLVIDHFRGGAGEYAAMEALAGIGMLAGGV
                     LLGVWGGGKRKIITMLVSTMVLSLAMTALGIVPAEVILLAYGLSAAVGLSISLLNGSM
                     MAMMQASVPFAMQGRVFALISAGATAMMPVGLLLAGPLADAFGVRIWYLVAGVPMIFI
                     TLAYTLSGSVLHIEDQVMKGSAKDAQHKEGGAS"
     gene            31769..32542
                     /locus_tag="PKM11_03515"
     CDS             31769..32542
                     /locus_tag="PKM11_03515"
                     /inference="COORDINATES: protein motif:HMM:TIGR00633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HNX47607.1"
                     /translation="MTLRLLCWNVNGIRAAYKKDLNGLLERDGADIICLQETKATVDQ
                     LPDGLRNAPGYHSYFVSPEEKKGYSGVGIYSKVEPNKVIPGFGQRRFDSEGRTLVAHF
                     DEFVLFNIYFPNGKASPERLRYKMEFYQEFLEVAKRTVEGGKHVIVCGDVNTAHREID
                     LARPKENGKVSGFLPQERRWIDDFLAAGFVDTFRMFDPSPERYTWWDMKTRARERNVG
                     WRIDYFFVDEGLRNRCRNAFILPEVQGSDHCPIGLELEI"
     gene            32539..32973
                     /locus_tag="PKM11_03520"
     CDS             32539..32973
                     /locus_tag="PKM11_03520"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024698.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX47608.1"
                     /translation="MSVVIRRMRSDDYAQVVDIWIRSGLPYQPRGRDSEERVREQLEK
                     DSSIYLVAEDHGKVVGVVLVTHDLRKGWLNRLAVPPEEQGKGIAKELVSRAEEDLSTL
                     GVNIFAVQVHEHNHRSRKLFAELGYQEHHDIIYCSKRYGPDE"
     gene            33032..33421
                     /locus_tag="PKM11_03525"
     CDS             33032..33421
                     /locus_tag="PKM11_03525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HNX47609.1"
                     /translation="MSVVLATDGRSHTSKAIDYALEYARLHKEALFVVFVIGPRHEEN
                     REGTVGDAKKHLEQIKARATQQGVETTVLLETGAPAESTIAVAERVNASVIIVGTSGK
                     TVLDRVLIGSVSDHVVHNSHCTVIVVK"
     gene            complement(33422..34165)
                     /gene="nuoB"
                     /locus_tag="PKM11_03530"
     CDS             complement(33422..34165)
                     /gene="nuoB"
                     /locus_tag="PKM11_03530"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: protein motif:HMM:NF013242.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HNX47610.1"
                     /translation="MLDIIERRVRDKKVVTEKLRLLQQQGHTRAPMADARCDLCGECV
                     PVCPASAISTQGDWSVDAGKCLFCGDCLPACPRDAISFSVKVPAVTQRSSFTLFRNVP
                     LPELKVQLRDEARKVLGRSLAIRMVDAGSCNGCEVEVNSLSNPIYDLERFGIKIVASP
                     RHADMLLVTGPVTRNMLPALMKTYRAAPEPRLVVAMGTCAISGGPFGGTYAAGNGVAE
                     ALPVDLFIPGCPPHPRTVVLALLEALGRL"
     gene            complement(34174..35706)
                     /locus_tag="PKM11_03535"
     CDS             complement(34174..35706)
                     /locus_tag="PKM11_03535"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: protein motif:HMM:NF012566.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HNX47611.1"
                     /translation="MRYYNVELLDSLPFPPFGYEERNGRLHLAVPDDLLRPLVSHLVR
                     KEEGELSNLYYVPSDNKVMALVLVPRHGIVVLESELEGEGYPSLTTEVPAANWYEREM
                     MEMSGITPLDHPDPRPLHLHEWPRHVHPLSPGFDKGAKVPFTGEAHHYRRVEGDGILE
                     VPVGPVHAGVIEPGHFRFSTAGEPILNLEVRLGYVHRGVERSLEGCTLNRALRLVERI
                     SGDNGVAHALAFCQAVEMANPVPDRAQLLRCIYAELERIYNHLGDIGGMATDVAFAVP
                     AAEASVLRERMLRLNANLTGHRLLWGSIAIGGAARDLDEGRRDLLEGAMVDLGLTFEP
                     MVDSLLGSPSFLDRVETTGTLALPMAKDLRATGPVARASGWDRDTRRDFPYGAYGRLS
                     FLVPVRREGDVLARLMVKVEEVRESISMVKQCVDHLHEGAIRSEMPLPDGFGLGLVEA
                     PRGELVHCVHFREGNIVRYKVRDPSFCNWPTMERAVLGNIVPDFPLINKSYNLSYAGN
                     DL"
     gene            complement(35703..37160)
                     /locus_tag="PKM11_03540"
     CDS             complement(35703..37160)
                     /locus_tag="PKM11_03540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HNX47612.1"
                     /translation="MVEILLLVPLITALLCAISRSERAIFVFSVAGSLITALVAIPYC
                     YQAFFEGPVDTGLWYLDPLSGLFMVVIVVITALVSLYSVEYLKHDRTEGEINIKDLRY
                     YHALLHLFAFSMLVVVVVDSLGLMWIAVEGTTLVSAFLVGFYKKSEAMEASWKYLIIC
                     SVGITLALLGIILLYASSVDALGANADTLDWSVLRSVAGQLDPALLKISFIFILVGLG
                     TKAGLAPMHTWLPDAHSQAPTPISALLSAVLLNCAMYGVLRVHILANEAVPGFSSSLL
                     IFFGLLSLAIATAFILTSRDVKRFLAFSSVEHMGIIALGFGIGGPLAVFGAVFHVLAH
                     SLTKTLMFFGAGNVIQKYRTREMKDIKGLGRTMPTTAALLVLGGAAIAGSPPFAIFIG
                     ELFIISGALVQGDYLVAGLFIALLVIIFAGMTYRIFGMVSGKPQEGLPEGELGKLRLL
                     PMLFLALAILGLGLFLPEVVSDALSAVVELFGVSA"
     gene            complement(37162..37821)
                     /locus_tag="PKM11_03545"
     CDS             complement(37162..37821)
                     /locus_tag="PKM11_03545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HNX47613.1"
                     /translation="MVDLLSIDTINFLAAAILLVSLLVMASTRMGQLVRSFAIQSIML
                     AAISVVLAHYTGSEHIYIVAALTLVVKGIIIPRFLMYSIDRLKVHREIEPLVGIPASL
                     LISGGLVIVAYYVTEPLISSAEAVTRNCLAISLAVVFIGMFMMISRRKAMTQMVGLLM
                     MENGLFLGIISTTYGMPLIVEIGIFFDVFMAVLIMGIFAYRINQTFETLDTTFLRRLR
                     G"
     gene            complement(37831..38772)
                     /locus_tag="PKM11_03550"
     CDS             complement(37831..38772)
                     /locus_tag="PKM11_03550"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="HNX47614.1"
                     /translation="MQLSDLLLNLAEVLFILLSSPLLAGVIRKVKSWMQCRQGPSVLQ
                     PYRDIWKLLHKSTVVSKEASWLFLIIPYVCLGAMVCLAMMVPVFTTGPSGGVGDMVAV
                     IYILGLFRFMMVLGGLEGGSSFGGMGSSRELMISAIVEPTLLLSIFSVAAISGTTDLS
                     AISAHFAGQGLSGISPTLFLASAAIFISLMAENSRVPFDNPATHLELTMVHEGMLLEY
                     SGRELALMDMASYVRLTMFMVILSNVFFPWGIALGMEAGELALGVGSIALKLLVLAIS
                     VALVESVMAKMRLFRLPNLLTISFTLSLLAVMSYYIL"
     gene            complement(38777..40759)
                     /locus_tag="PKM11_03555"
     CDS             complement(38777..40759)
                     /locus_tag="PKM11_03555"
                     /inference="COORDINATES: protein motif:HMM:NF012581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="HNX47615.1"
                     /translation="MLSAVLPALMLSLPLLGTALALLLRSEKHRVYSYLCSAASAVSA
                     AFWSLLVLLNGTSTFVLDVPSAMGDYAIRLDALGALVLLITSLTFACVAMYSLFSREG
                     ITSRGASIFNLFMLSVLLAMVADHLLLLLVAWEATSLTSFLGAWGSREDQDTAAGWKY
                     LAVTHFGAALIIVALVFLSTTSGEVRLSEMHGLSATLGPLTSAVVILLAFLGFGSKLG
                     ILPLHIWMPDLYSRSPSTITALLSTAASNVAVLVLVRIIFDMVGVGDQHMLSLLVMGM
                     AATTALWAAWQALVQRDGSRVLAFSSMENMGLILLTIGAAMLFQSYGAAEPAAFAIMA
                     AMFHLINHTVFKSLLLMGVGTVRRAAGEWDLEKLGGLARTMPGLSAVFLFGTLAVAAL
                     PPFSGFVSEWAMFKSLMHAEPIADPLIRIALPLAIAVMALCTAIAAAAYLRLFGFTFL
                     GRPRSNGAARPRPLDRVEIFPLVPLAALCLLLGVASFPLLEELTSAVSPLVGATGIQV
                     IEGYSINFLHQGGLNPLGLSALLAGAILVVFLVLRATGKRKVVLGDTWDCGTTLDRRT
                     QYTPTGFSQPLMRVFKQVYRPHTEVKEEPHPSIYIRTVRFEQALPEMFTAHIYQPLVA
                     ATVAVAMRVKRMQSGSIQAYLAYLMIILIVLLVVLR"
     assembly_gap    40788..40887
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <40888..41099
                     /locus_tag="PKM11_03560"
     CDS             <40888..41099
                     /locus_tag="PKM11_03560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47616.1"
                     /translation="KALEVGIQVEISSVKMYRGAALMVEEPGVRRLLEKLASIEEGHR
                     KLLEESMQLLRDKGAWYGYSPILEG"
     gene            41282..>42451
                     /locus_tag="PKM11_03565"
     CDS             41282..>42451
                     /locus_tag="PKM11_03565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HNX47617.1"
                     /translation="MVKLPNIDREVQACLQCGYCIRTCETWRQTPWESVTPRGKIFYI
                     SQLGKRTAIDKMLGRKVEIDDEFVEALFMCTTCAACATVCHVGIDFAEFWEKVREWCI
                     DNGHGPMPAHVTIRERLEEGRNPYNEPMDKRGAWYPAVPKADNPDVVFFAGCTASYRM
                     QNLAKSSVIFLNRCGVSTNIMEGDEWCCTSPALRTGQTGLTYRFAEHTISTVEHMGAK
                     AMVTACAGCYKTTVHDYGKFYSHPTFEVFHFAQYANKLLKEKKVKYTKELKAKVTYHD
                     PCHLGRHAKVYDEPREVIKSIPGVEFIEMKNIRENSRCCGAGGGYKSQYNDMAIAIAV
                     ERVKEAVATGADILATTCPFCVLNMTQAAKKIGAKIKVMDVSEMLVMATEPEAPVE"
BASE COUNT         8744 a        12664 c        12534 g         8209 t
ORIGIN      
        1 cgattccctt cttcttcgca tgatcaacga gggtcgatga aggaaccttg agctgccgag
       61 cggcgtccga tatgctgcga gcgttgccgc tgcgtaggag ctccacggcg aggcctacgt
      121 tgacatcttt gcgccgaccc ttgccccagg agccgccctc cttgagacgg cggtgtatgc
      181 cctcggagac gcgctccccg tggtgttctc gttccatctg agcgaaggca agcataaggg
      241 tgtagaagaa tcggccgccc ggggtggtgg tgtcaatctg atccttgacg aagatcaggc
      301 cgcacccgac atcctgcagc tgctgcgtgg cctgcaagcc gtatagggct gagcgcatga
      361 agcggtcgag gcgaaggcag atgattgcct ggaaccgacg tttggacctg ttggtggcct
      421 ccttcatcat gtctttgaat gccggtcgcg ctgggtcctt gccggacctc ccctcgtcca
      481 cgaatgtggc caccacctgg tgttcgtaga tctcgcagta ttcgcggaga ataaggagct
      541 gcgtctcggg gttttgttct ttgtcgtccg tggagacccg ggcatatagg gcgaccttca
      601 tggttctcta tccataggtg ccaccttcgc caattgatgc gacagcgtct catcctcttc
      661 atcctctcca ccatgggtcc aaggtttgaa ctgataccac gtcttgttca atggacggat
      721 gatcccgaac gtcttgaacg tcctcgtgta gctgctaatg gtcctgtcat tacagccgaa
      781 gttctctgca atgagccgct cgaataccgc acgggggatc tgccccttat tcaatcgcgc
      841 tagctcatcc aattccggtc cgattatccg atacacattc tcgaatttcg ccatactatc
      901 cctcgcgttc cctgatttgt gtgcgtgagt tcgggagctc gttggtgcac gggaaggcgg
      961 gatggttgtg tgttgtgatg tcgtgtaccg ttttacgccc aaccaccatc cccattgcag
     1021 cctgggagtg gtcgattggg ctgacagagc cttcgctgtt cggtgggtcc cgaagagtcc
     1081 gcaacatcat taaaagcagg gggcggttaa gccatgttaa gccagcgaca gaaatgactc
     1141 cggacaacta tccatatctc atcattcatt cgccttgcgc ctgccttttt gctgcggaac
     1201 cttgtgacca tgtacacgac acaaccacat acacaaccaa caccaacacg cacaccggca
     1261 cgccccctca tgcctttccc cacacgcaca cgttttcctg ggaagagtcc gaggcaccgc
     1321 gcctcccggt gttggtttaa tagaatgaag agcggtcgct gatcaacagc cgcgccgccc
     1381 ttttgtcctg gtgcatccca tcctcgacgg ttcccttgtg gaatatcgag aacgaccaat
     1441 gaatcaagga ctgtaagtaa atgggcgctc atggtcgctc ccccatggat tcgccgtaga
     1501 aggccttggc tatcaagacc tcggcgtcgg cgagctgctg gacacggtta atcttgaacc
     1561 gttctaattt tctttgaaaa tcggcggtga gccagatagg ggcggagacc gtgtatccga
     1621 ccgggcccac atcatatcca ttctgcgttc tacgatgtta tcagggcgat tgtcgaaaaa
     1681 accaaattcg gaaaaggttt ggatcgaccg ttgcctcccc cggaggatca gttcttcgga
     1741 gcggcgtcct tggggacctt gtcggccttc ttgaggttct tagccatgtt gtcacctctg
     1801 gaccatggac cggcgctcgg tctcttaggc agttccgagc caccatgtag gttttagtat
     1861 cgcaaatcgt aataatcgag agcgcgttct ttgctctggc ggaaggatgc cgccaaacct
     1921 actctttgct cttcttgacc ggaatgacca tgtccttggt gaaaagcccg gaccggtgcg
     1981 gcatgttggc cttggggcaa tggggcttcc gacacccgac ggtatcggcc aaattcccca
     2041 gcgggcagac ggaccacttt tcgcatcggt tcatcaggac accttgagga cggtataggt
     2101 atgtccccat acaatgattt ccgaacttgg aagactaccc cacggttaaa tccctgttag
     2161 accattgtcc gccggtctta ccgatgagcg aatgggaatc gttcttaccg aagtacgttt
     2221 gcgagcgact gcagagcatg atggacgtgc agttcgtggt cgacctgggg atcgagacca
     2281 gatcgatcac caaggacggg gaggtccgct gcgtcatgaa cgtcagcgac aagctcaacg
     2341 cctatggcgg ggggcacgga ggggcggtgt tcgcattggc ggaccaggcc ttcgccttgg
     2401 cctcaaatat ggggaaggaa aaacaggtgg cgatggtcgc cagcatcaat tacatcaaac
     2461 ctggaacggg ggtcctggaa gccgtggcgc gccggacatc cgagaccaag aagacctcgc
     2521 tctacgaggt caaggtgttc gacgatggaa aactggtggc tgttttccag ggcactggct
     2581 acaagatcgg ggagaagcgc cctacagcct cgcgctgatg agaatgcctg aacgatgaac
     2641 ggagctatcc ttcgggcgcc caaaatattg tttatagaag ggcacgagaa tattctcctt
     2701 ggggatcgtc gtgaaggtcg agatctatca tgcgtcgaag tacggcaacg gggagaaggt
     2761 ggtagcttac ctgcaaggac ttctggtggc caagggtcat caggccgact atcgtcatat
     2821 tagggacgcc agaccgaagg atatgcctgc cgcggacctg tacgtgttct gcgcccctac
     2881 ccgtataggc aaaccgatcg gcaagatgag aaggttcctg aagaaggcca ggttaccgga
     2941 gggagcgaag tatgcgctca tagcaacgca cggggagccg gtgccggaca agaagacggg
     3001 agagatgccc gcgcctgagg ttatcgagaa gtaccagcag aacctgccgg ccatggaggc
     3061 catcctgaag gataagggag cggtcaaggt ggccgaggtc aaggtgtacg tccagaacac
     3121 catgaaagga ccgttgtcgg acggctggga gaaggtcgtc gaggggttcg cctccaagtt
     3181 gctttaaaaa agagagatgg gaaaggggtt tggggttact tcttcctcag gaacagcact
     3241 gccgcaccgg ctatcgccgc cacgatgacg atggcgatga tgatgtatag catggtgttg
     3301 tcaccgctgt ccccagcatc ggcggatggc gtggcgtcaa ccgcgtcggt ggtggtcccc
     3361 tggccgatgg agttgacggc actgatcttg taccagtagg tctggccgtt gaccacgtca
     3421 tcatccgtgt aggtgttcac atttcccagg gtgacgagca cggtcgacac ggcgccctca
     3481 ctggtgccgc gatagatcac atagccggtt atcggagaac ctccatcatc cgtcggcgcg
     3541 tcccatgaaa gggtgacctt ggcatcgcca gcttccgcct ccaggttgtt cggtgcggac
     3601 ggaacggaac tggtcgacat cattatcgcg ttggacctgg cgccctcgcc cttggcgttg
     3661 agtgcgctga ccgcgtagta gtactccgta cctgccacga cctcgtagtc tgtgtagttc
     3721 accacgttcc cgagggccgc cagtaaggtc aggttggtgg cggatgttcc gcggtacacc
     3781 ttgtacccgc tgacgttcca acccccgtca ttctctggcg ggtcccagct cagaacgatg
     3841 ctcgtgccat cagcagacgc ccccaggttc atcgggaccg acggtacgga acccagcagt
     3901 accgacaccg tgttggacct ggggccttcg cctacgccgt tcaccgcgct gatggcataa
     3961 tagtacatga tgccgttctc tgcggaatag tcctggtagg tcaggacgtt gcccagggtg
     4021 gaccacagca ccagcgctcc ggacgcctcg ccccgataca ccttgtagtt ggtgatcggc
     4081 gaaccgccat cgctcagcgg ggcctgccag accagctcta tcctgctgtc gtgggcatag
     4141 gtgaccacgt tggtgggcgc ctcgggtacg gataaagaca gagtaggtgt ggcgctgacc
     4201 tcggtcgaca gaggaccttc gccatatccg ttgaaggcgc tcaccttgta gtagtaggtc
     4261 accccgttgg tcacggtcaa gtccagatag ttcatcgacg agttcacgaa ggtcaggagc
     4321 gtctctgttc ccgaggacgt gccgcgatag accttgaacc cttgtattgg tgagccgccg
     4381 ctgtcgacgg gagagttcca tatcaagctg acgctcccgc tgccaggagt ggccgagagg
     4441 cccgtgggcg cggttggcgg ggtctgcgga acgatggtca cctgctgctc tgcgcagaac
     4501 ggccctgtgc ccagaacgtt gtaggcagcg atggcgtaac ggtgaacacc caaagctaga
     4561 ttggtatcgg ttcggctcag gtcgctgagg ccgatgatcc tttccacctc tccgctcgga
     4621 taggaatgaa ggacaatgta gcctagcacc ggaggcccgt tactgctgac cggcgctgac
     4681 caactggcct gtacgtccag tccatcggcg accaacgtta ggccgcgagg agcggttggc
     4741 gcggccttct gattggccag catgatgcgg ttgttcgtcc agtcgatgta acaaacgctc
     4801 agtacgccct ggtcgttgat gtccaaggcg ttgatctcgc cgaccaggcc gttgcggtcc
     4861 accgtggtcg tccaccaaga tccgccgatg tctaccgcgt atctcaggtc accgttcagc
     4921 tggtcgtgat aggttatgtg cgccttgcca gctttatcaa cgtctatcga ggagcggctt
     4981 ccagcgttcc cggatatgtc cacatcgcgt ttggtgaccg aggccccctt gaccatcgcg
     5041 tatttcaggt agtggctgct ggtgtcgtaa taactgatat gcgccgcacc gtcgcctccc
     5101 aacgccaggg aggggttttg gcctttgaag acggctccgg tgtccacgtt ggtgatggcc
     5161 caagatccag cggtgttgtt ggccagcttc agccccacca acccggtata gtagcttatg
     5221 aacgcctttc cgttagcgtc caccgcgata tcggtctgag ttccggagaa ggccgtggtg
     5281 tccacggtta cggtcgccca tgaaccgcca gcgttggtgg cgtacttcaa gcggggatcg
     5341 ccgctcgagt tccggtagct tatgtgcgct ttgccgttaa cgtccagggc gatggacgtg
     5401 aacattccga cgtcccccgt ggaatccacg acggtcttcg cccacccgct cccggtgtcg
     5461 accgcgtact tgagatcgcc accggtcgcg ttgtaatagc ttatgtgggc ctttccgttg
     5521 gcgtccaccg ctatgctgca atactgaccg acgtcatcgg cgttatccac gagggtgact
     5581 gacgcgaccc cacctctgtt ggtagcgtaa cgcagcgctg tatcgtgcgt gtcgtagaaa
     5641 gcgatgtgat acgcgccaat gtcatccctc accatggaaa gatagttctc cggtgccgcc
     5701 tcgcccgtca ttctgtaaat ggtactgaag tcccacgggg agttcgtggc atatccgacc
     5761 tgggagttgc tggcgtcatc atagctgatg tgcaccttgc cgtcggtccc gatagccagt
     5821 ccagattcgg atccgaccat accatcgtga tccaataccg atacggccca ggatccgcca
     5881 gcgttggtcg cgtactttag gtcctggtta gtgttgtcat aatagctgat gtgcgctttt
     5941 ccgtccaggt ccagcccgat ggagctgtac tcgccgaccc agccgatgga gtcgacgacc
     6001 gtcgggaccc atactcctcc agattcgaac gcgtacttca ggtccttgtt cgccgagtcc
     6061 atgtagctta catggggacg gccatttcgg tcaacggcta tcgaagtatg ctcacccacg
     6121 ttcgcagagg agtcgatcgg ggacagcacc cagctcccgc cggcgttggt ggcgtagcgg
     6181 aggaccttgt tggtctggtc acggtagctg atgtgcacct tgttcgaagc gtccaatgcc
     6241 agggatggat agcgtccaat gtcagcggag gaagaatcca ccgtctcgtt gacccaggtt
     6301 ccgccgacgt tattggcgta cttcagggtg gcggtgaacc cggaatcttc gaagtatgag
     6361 taggcgatgt gcaccttgcc gtcgctgtcc acctgcatcg acaggtcgtt ggtgctccag
     6421 ttcggtttgg tgtccgcgac cttctccttg acccagggat tgccggtggc ctttgtggcg
     6481 tatcttatct ccccgctgtc cgcagcgtag taggcgatgt gcacctggtt gttagagccg
     6541 agatcgatgg acgtcgtccc tccgtaatcg ccggtggtgt tgtccaccat ggtgtaggtc
     6601 cagcttcccc agaagttgtt cgcgagccat aactcgtatc ctgcgttcgc cgtgtagctg
     6661 atgtacgcgt tgttgtcatc gctcaacgcg atgtcggtgt tcccgaagca catgttgccg
     6721 gtggtccccg ccagctcctc gaacgtccaa acgttctggc tggtatacag aagatcatct
     6781 gaaccgccga aataattgga aacaccgatc ttaccatttg gcccgatggc gatagaacaa
     6841 tattccccta ccgtactggc acccgcgtcg tccacggtgg tgcagttcca acctccgtcc
     6901 aggaacctgg cgaccttgag gttcgagttc gtgctatcgt aatatgcgat ggacggcgct
     6961 ccatcccggt ccacacagat gctggaatgc tcgccaacaa tagccgtgga atccaccgtg
     7021 gttatggaca ggtcccattg gacaccgtcg aagtgttgat atttgagatg gcccgcacca
     7081 tcaaaatagc tgacatgcag atcggtacca cctgagatgt ccattgacgt gaagtaaccg
     7141 cattcgccgc tatcatcaag ataggagcgg gaccagccac tgggatattt ttgcgcccat
     7201 ttgagggcga cattgaactg atcgaaatac actatgtgta taatcccata atcatcgacc
     7261 acgatggatg ggtacatgcc cacctctaca ccgctatcgg ccgtctcgtt cacccatgcg
     7321 cccgcggtat tgttggcgta cttcaggtcg gtgtctgaca gcgcgttctc cacgctgtac
     7381 gctatgtgaa cgcgatcgga cccgtccacg aatatgtcat tgtagcaacc cgctcgataa
     7441 tgcttgtcta ctaccgtttt gctccatgaa ccgccagcgt tggtggcgta tatcaggaac
     7501 tcgtcctccg agttgtagta gctcatgtag ctgatgtgga cctcattctt cgagtccagg
     7561 gtcaggctga tctccgagta gaggtccgtg ctcacctcgg tgtccaccgt ggtgatgttc
     7621 cagaacccct cggcgttagt tgcgtacttt agggtgccat cttcatcgtt gcggtaggcg
     7681 atgtgggcat aaccgaagtc atcgatggcg agagaggatt gtattccaac aatacctttt
     7741 gcatccacca cctcaactcc ccaaccccct tcggtctgga aaacgccagc aggcgccgcc
     7801 tccaccccct gcggcaccgc cacgatgacc gtcgtggaca tgaccatcaa taccgcaagc
     7861 aatatggcgc tagccctccg gctcagaaaa gagacccccc cgcgaactat catgcggaat
     7921 acatttttcg gaggattata taatgactcg acatcgatta taacgataga gaacatccag
     7981 tgcttgtcag gaccgatttc ttagctggca tcatcgcgga tgattaaaga aagggtatgg
     8041 aagaggtttg gccaggtggt cattttcttt ttcgtaggat gaagaaggcc acaccggcta
     8101 cggccgccac ggcgacgatg gcgatgatga tgtagagcat ggtgttctca ccgccctcgt
     8161 cgtcatcatc gtctatccct ccctccacgg tcggcgtggc gtgcactgaa ccggtcaggt
     8221 tcccttcgcc cgcgccgttc accgcgctga ccttgtagta gtaggtcacc ccgttcatca
     8281 ccgaatcgtc caggaagtga gtggcgttcc cccgttccaa caacaggacg atgttgctct
     8341 cggacgtgcc ccgatagatg atgtaacctg tgatcgggga ccctccgtta tcattgggtt
     8401 ggtcccaggt cgggttgacc gtgccattgc ccgcgtcagc gtccaggttc ctaggcaccc
     8461 cggggacata cgccaccgcc tccaccgtga cctccaccgg ttggctcttc attcccacgc
     8521 caactgcgtt caccgccgcc acccggtaga cgtacgttcc accgagagcg ctctgatctg
     8581 tcgcctcgtg cacgtcgctc accgagaaca acaggacctc ctcacccacg gcgtcgctgc
     8641 gattgatgtt gtagccagtg atgtcgtaac tatggtcctg atacgggaac ttccagctaa
     8701 gggtgacatt tccttccccg gcgaccgctc acgctcacat gacaataatc caatcatcct
     8761 tcgtccagac gttcattctg ctcacccgaa gcttgacctg ttagatttaa tacggtaata
     8821 ctgttaaccc ggaagccacg gaagcggaca gatggcagag gagataccac cgaccggcac
     8881 cggcaacctg agggattacg aggaagcgta ccgttccttc aactgggcat cccttcacga
     8941 tgagttcgac tggtctcgag gcggccctta caatgtggcc gcggaagcgg tggaccgcca
     9001 cgcccgggaa cgcccggaaa aggtggccat ccattccgtc cgggccaacg gggaggtgca
     9061 atccctgacc ttccgcgata tctccagatc gtccagtcgc ttcgcggatg gcctgagaca
     9121 tttaggagtc aagagagggg accgggtctt cgtctacctg gaccgccgct ccgaactttt
     9181 catatcgatc atcggaataa cgaaactggg cgccatagcc tgccctctgt tctcggcgct
     9241 cggtccggag gcggtcaagg accgtcttat ggacgggaca ccgtcggccg tggtcacctc
     9301 accctatctc tttgatagga tctccaaggt gctcaaggac gtctcgcaga tgccattggt
     9361 ggtctgcgtc ggggataaca gtccgccgaa caccatctca tattcccagc tcctggcctc
     9421 tggttcgcct gattttaaaa cggtggacat gcggccggac gaaccgtaca tcatccacta
     9481 cacgtccggt tccaccggca agcccaaggg agtggtgctt ccgcaccggg ccatggtcca
     9541 gcagctttcc ggagctaggt acgtctccga cctgcgggat gatgacgtct tctggtgcac
     9601 cgccgatccc ggctgggtca ctggcacctc catgggcata ttcgggccat ggtatctcgg
     9661 gaccaccatc atctccttcg aagggcgctt cgacgcccgc tcctggtatt cgctcgtgga
     9721 tcgcttcaag gtcaccgtat ggttcaccgc gccgacggcg ctgcgcatgc tgatgaaggc
     9781 cggggacgag gtggtcaggg agttcgatct ttcctctttg aggcacatgt gctccgccgg
     9841 tgaacccctc aacccccatg tggtccgctg gggaatggag gtgctgaagc gccgcataca
     9901 tgataactgg tggcaaacgg agaccggagc accgtgcatt tccaacttcc ggtgcatgac
     9961 cgtgcggccg ggctcgatgg gcaaggcggt gccgggcatg gtcgccgcca tcgtcgatga
    10021 gaacggcatg gagcttcccc acggcaagga ggggttcctg gccctgcgcc ccggctggcc
    10081 gtccatgatg accgggatct gggggaacgt caccaagtac cgcgagtact tctacgtccc
    10141 aggctggtac gcgtcgggag atcaggcctt caaggacgag gaggggtaca tctggttcct
    10201 gggccgggcg gacgacgtca tcaaaacctc cggcgaaaga ctgggaccct ttgaggtgga
    10261 atcggccctc atagaacacc cttccgtggc cgaatcggcc gtcgtcggca agccggacga
    10321 gctgcgcgga gagatagtca aggcgttcat agttttacgt ccaggcaacg atccgtcgga
    10381 aggcttgaga caggatataa cgaacttcgt tcgcgtgcgg ttggcctatt atgcttaccc
    10441 cagggagata gagttcgtgg attccctgcc gaaaactcgc tcaggtaaga tcatgcgccg
    10501 ggtgctcaag gccaaggagg gcgggcatga gaccggcgac ctgtccatgt tggacgattg
    10561 agacccgttc ccgtatcaac taggcgatgt gggaccgcaa cctgctaata acgaggtcga
    10621 gaatcccttc gatgatggga ttgttagaca aggacccctg ttggtctcgc cggaccgccg
    10681 gcgcgctgat catggtcgcc gccttcatcg tgctgatggg catcatcacc ggggaggcga
    10741 tgtatcctgg atatcatacc ggggataacg acataagcga cctggccttg gaagagccgt
    10801 ccgcgaccat cttcaactcc accatgatag tgggcggcat aatgttctcc ttgaccgcca
    10861 tcctcttgcg ccatgccggg cttccccggt cggtcaccgt ccccgccttc ctcatgggac
    10921 tcggaggagc gggggtgggc ctgttcccgg tctataccgg atcaccgcat tacgtcgccg
    10981 ccctgatgac cttcagcatg ggcgcggtga ccgccctgat ggccggccgt accgccgacg
    11041 ccccgttcaa gtacatctcc ctggcgctgg gaaccatcgg cctgatctcc ctggtggtgt
    11101 tcgccatgat gtggggagga gagccgatcg gaccgcttgg cgagggcggg atggaaagat
    11161 gggtggccta tgccaacatg gtctgggcca tcggcttcgg cggatacctg atgaacagcg
    11221 gaccagaccg ttccaggtcc aaaatgtcct gcaatcgccc ctaggcgtca agcagcgaaa
    11281 gttagaatat ccgccacccg ctagtttcaa gcgaaggtgg atccggtgga cctcgaccaa
    11341 gccatacaga tgtgcaggtc ggnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11461 nngatatgat cagatcgaag gccataccgg tcgggaaggc acccccggtg gccgactcca
    11521 tctacctctg gagggcgaac gccggaaaat tggctcaggc cgtgagccaa ttggaggatg
    11581 acgaataccc ctgaccaggt aatgctgaat aggcgcggtc cgataggtta tgggataacg
    11641 tgaaagagct tcgtattcga catcatcatc tgctgtgcac cagcaccttc gtcggccatg
    11701 gatacgacgg gcgtttcgtt accaatatgg agaaggtggt gtccatcctg cggtccccgg
    11761 aagaactggt catacatctg gacatcagat gcgatgacct ctgttcgtca tgccctcatg
    11821 ccgttcgggg cgtgtgcaag gaccacacgt cggtggtggg aaaggaccgt tcggcagcgc
    11881 ggttcctgag ccttccggaa gaaggatcgt tcccggccgg ccccttgcta gacatggtga
    11941 agaaaaggtt gcgagctctt gacgacatcc acctggtgtg cggagaatgc gagtgggcgg
    12001 acctgtgcaa cgcccggctg agcacgttgc gcgccacggc aagcgcccag gaccggcccg
    12061 taaaaaagct ttagtaacat ggcctttttg tagctagcat ggacgccgag ctgaggatag
    12121 tgatggacat gaccttgctg atggtcattt ccggcctctg ctccctgttg ttcgccagga
    12181 tcaaaatgcc tccgatcctg ggctacctga ccgcgggcat catactcggt ccgaccatgt
    12241 tccccgacct gtgggtggaa cagaccacgg tgatggtgtt atcgaacatc ggtatcgtca
    12301 tgctcatgtt ctggataggg ctggagcaga gcgcctccaa gctcaagcgg gtcggttccc
    12361 ggctcatcat gatcgtgacc ttggagatga ccctggtggt catcatcggc tacctgggcg
    12421 gcatggccct ggggctgggc agcaccgcct cgatattcct gggagccata atctccggca
    12481 ccagcacggc ggtggtggtc ggggtcctgc aatccgtcaa gaccatagac ggggagcagg
    12541 ccacggccat catgagcatc accgtattcg aggacgtggg acaggtcata atcctgtcct
    12601 tggccgcccc gctgctggcc ggcgattccc cggccttggg atcgaccatc aacatggtca
    12661 tcggcctgat cgtgttcttc ggactttcaa taatgatcgg gttggcgctt atcccccgca
    12721 tcatggaccg catcggggac cgctatccgt ccgagatggt gttcatcgtg gcggtgggaa
    12781 tggtattcgc catggccctt ctctcgtcgt cggtcggcct gtccatagcc atcggcccgt
    12841 tcctcatggg gctgatagtg tccatgtccc tttacagcga gcggatcaag gccaaggtca
    12901 tcccggtgaa ggaactgttc atggcggtct tcttcatctc catcgggctt cagatggacc
    12961 ctcgtatggt catcgacaat ctgcctctgg tggtgtccat cgccgccctg ttcatcttcg
    13021 gcaagatgtt cgtcctgatc atctccacct acatcttcgg ctacaaggcc aaggacagct
    13081 tcgtgatctc catatcactg ctggccatgg gggagttcgc cttcatcatc tccaagatcg
    13141 ccctggacgc cggactgctg tcccaggagc tgtactcctc ggtcatcggg gcggcgctca
    13201 tcaccatggt caccctgccg ctcacctcca agttccaagg gccgatttat tcggcgatcg
    13261 tacgtatcac gcccgttaag ttgcgttccg ccttcgggag gatggactcg gtcaaggagg
    13321 cggccacgtc ccggaacgtg atgatgtccg atgaccgcag gaagttgagc ggccacctta
    13381 cccgcatctt catcgattac ctatacatcg tcctcgtaat gctggtgttc aacctggtga
    13441 gcgaagtgaa caccgtgatc gcggacgcgg cgggcgacct gggtgtgctg cctggggccg
    13501 ccctgctctt catcatgctg ctggtcatat ccccggcggt ggtgagcgtc taccggaacc
    13561 tgaagaaggt ctccgcggcg ctcacggaga tggccatgcg ttcccaacgc atcgccgagg
    13621 gcaatagaag gaacgtttat cgcatgttct tcgacctcag cgagatcgtc atgttcctgc
    13681 tggtgctggc actgatcatt cccttcgttc cttccgggct ggtcaccacg cccctgttgt
    13741 tcgggttcat cgccatcgtg gtggcggtgg tggtcatact ggcctgggat gccctgagga
    13801 actcctatgt gcggttccta ggaatggtca ctggtaacgg tgctaaggac ggcccggaag
    13861 agtgaggtcg ctcgaaccgt ccgcgctccc ctcttcactc ctctttgatg gcctttaaga
    13921 gatcgtccac cgggatggcc gccatggtca ccgtttccag tgtcccccgg gaacctagcg
    13981 ccaccatgat cttgaccacc gtctcgttgt tcggcgcctc caggatgttg atgaaatcat
    14041 actttcctag gagggcgtac tgctggatga ccttggcccc catcttggtg atctccttgt
    14101 tgacctcctt caaacgctcc ggcctgctct tcagggtctt acgaccttcc tgggtcagtt
    14161 tcgacattac tacgtatacg cccattgttt ccaccgtggt aatcttggcc ttggcaggaa
    14221 atataacttt gccgagctca ggccgaaggc tcctcgtgca ccttcacgtt gcggaagttg
    14281 aaccagaagg cggtgaccgc ggcgatgtag atcagagcgg ccaatacgaa agggagagcg
    14341 aaataaccgg cggccagcat ggccccgccg atcacggtgg tcacgctgtt cggcaccctc
    14401 cacactatgg agttaatggc gctggccagt ccacggtcct ccttgtccac gatgcccatg
    14461 agataggagt ccattatcgg cccggccatg ttcatcgtgg ccgagcggac caggtagatg
    14521 gcgccggccc agatggcccc cggcatgaag gggatggcca gcatgaatat ggtggagaat
    14581 ccctgggtca tcacgatggc tgggacctga ccgtagcgat gggcaatgcg gggactgaat
    14641 atggccgccg cggctatgga gagcgatgaa agcgctagca aaggccccga gtacgagtcc
    14701 gggatgccgt aacggaggta gaaccaggtg ggtatgagag gtattatcag acccgccccc
    14761 agcccgatca gtgtgttgtt cacggagaag cgcaccaggg tcttcttgct cctctccttg
    14821 aggaaggacc cccggcgcaa tttggccgaa ggcgtggtgt cgtgatagtt cttcagcagg
    14881 aagtggacgg tgaccggcga tatcagggtg accaggccga tgaacacgaa ggcccaggag
    14941 tgcacctgct gagaggtcca tccgccaagg tccatgatag cggggaaggc gaaaggcagg
    15001 gcgaaaccca gtccgacgaa cgccccgttg acgatgaagg acatggagaa cgccatctcc
    15061 cggttgtcca cgttggtctg gtcggcgatc atggcgttcc aggtggacaa tatggcccct
    15121 tcggccactc cggatatgat ggccgccgcc aggtacagtc ggggatcggc ggagaaggag
    15181 catatgaaca tggagaaagg aagcagggcc agcccggcca acagcaatct ctttctgccc
    15241 agccgatcgg acataagacc gaatgggatg gcgcttatga tcatggccaa ccccgagagg
    15301 ccgattatca gcccgacctg ccccgaatcc acgccctgct ccggcaggta ggcggcgatg
    15361 gcggtggtca ggtaaccata gcctatggag ctgaaggacg tgagcagtat caaccatttg
    15421 acctgggccg ggaccttggt ccccttccgg tcactgaact tcgacctgac gctcattcgc
    15481 tcacctccaa cttcccctgg accatttaac ggcctgaaca tcgaataatg ttcaggtatc
    15541 agatacttgc ggtcccctca ccgacacatt attaattctt agcagcgtat tttctccgaa
    15601 cccacatgct gcccatcgcc ccactgatga tcgaacatcg cctgattgag agcatggccg
    15661 ccgtgatgaa cgagcaggcg gaaggattgc aggccggcca ggagctggac ccccgcttca
    15721 tccccgaggc ggtggatttc atgcggacct acgcagaccg cacccaccac ggcaaggagg
    15781 aggacatact cttcaaggtc ctgaggggaa agaagctgag cggggagcac cgccaggtgc
    15841 tggagagatt ggaggcggac cacgtcaagg cccgggagat ggtggccagg ctatccgccc
    15901 tgggggatga gtacctgaag ggaagcccca gcgcggcgta tcaggcggcc ctgctgatga
    15961 aggacctggt ggggttctac cgcgcccaca tcgagctgga ggaccagggg ttcttcgttc
    16021 cggtgatgga gtatctttca gcggacgaac gccaggcgat gctcgaggag ttcagggact
    16081 tcgattcacg gatggtccac gagcgctatg ccaagaccgt gcagcgcctg ggcgggggaa
    16141 gttcggttca tctggctcgc gatgacgggg accgctggcg ttgccgggtc tgcggttacg
    16201 tctacgaccc ccgggacggc gacccggaga acggcgtgcc cgcgggcacc tcctttgccg
    16261 accttcccga cgactgggtc tgcccggtct gcggcgcggg aaaggacgcc ttcgagcatc
    16321 tctgagggaa atgattatct tgagcggcct gccatcccca tagcatgagc gaggagccgg
    16381 gacaggattt ccagagggag accaagcatc gccgggaccg cctggtcggc cgctacatgg
    16441 atttcgatag gagaccggag acctacaagg agtacccgga aaggccaagg accatcttgc
    16501 cggagcccca gcgacccgcc tcctccttgg acaatcttct gaggacacgg cgcagcgtgc
    16561 ggcgcttctc caaagacccc gtttcgctgg atgagctttc ctacctgctc tgggccagcg
    16621 atggcatcag taaaaaggct ggcgtacacg agctccgcac cgcgccgtcc gccggagccc
    16681 tgtacccggt ggagacctat gtcgccgtca acgacatccc cggcctggcg ccgggaattt
    16741 accattactc agtaaagcac cacgctctgg agctggtccg gaagggccgc ctgggagagg
    16801 agcttgcccg cgccgccttg gaccaaggta tgtgcgcctc ggccccggcg gtgctcatgt
    16861 ggaccgcggt gttcgaacgt tgccgctgga agtacgggga aagggcgtac cgttacgttt
    16921 acctggacgc cgggcacatc gcccagaacc tggccttggc cgcggtctcc ttgggattgg
    16981 gaagctgtca gatagccgcc accttcgacg acgaggtcaa cgagcttctg ggcgtcgacg
    17041 gagaggagga gagcgtgctg tacatgagcg tgatcgggag accggcgaac agcgcaaacg
    17101 attaatcatc atcccccatt tacatcctga tgctctgtcc caactgcgga aaccatccct
    17161 cccccaacga caaattctgc atggaatgcg gatcgcccaa ggcgaatttt attgacgata
    17221 gcgttccccc ggcccagacc gccgcccctg cacagccgga gcctcgacct gtaagccagg
    17281 tgcaaccccc ggtcgctccg ccccgaccgg aggaacctcc ggcgcaacga ccgccgcagc
    17341 cgcctccggc acctcaagcg ccgcctcagc ctcaatacgt accgccgcag ccgcctccgg
    17401 ctctgcaacc tcagcaggcg ccaccgggac cgcgagcacc ggcccagcca cagtacgcac
    17461 cgcctcaacc accccccgca cctccggtcg agcaaggacc ggtgaaccgc ccggcgcagc
    17521 cgcaaggccc ccccgcttac gcgccgcaac ctaggccgca ataccagcaa ccttatcaac
    17581 aaccctacca gcaggcgccg ccgacggcac ccccccaata ccagcaagcg taccctgcgc
    17641 agccccaacc gctgccgcag atgatacctt atcagccctc cagcaacgag atgacccctt
    17701 atgggagaag ccagatcgga cagtaccagg tctacgtccc gcccaaggcg cccaaggccg
    17761 acatccaact tccccccacc ccgatgatac aggcgcaagg accgataatg ccggcacccc
    17821 agccgccagc gccaccgacg ccggcgtcgc ctcaaccgca accggcgcaa cagccgtacc
    17881 agccggcccc tcaggcgccg ccgaccccgc ctcagcctgg cccttgggcg agccagcagc
    17941 ccccggcgca acagccggtt cagccgtacc agtcggcgcc tcagccgcca acggtaccta
    18001 acagctatcg accctatccg ccggccgctc aacaatcatc caacgctccg ccggcgccct
    18061 atcccggacc ggcgccccag ccacagtatc agcaacctta ccaacagccg taccagccgg
    18121 cccctcaggc gccgccacag gcttacgggc cgcagccgat gggacctccc ccgggcggaa
    18181 tgatgctcat gccccaggta gccgcggccg ccatgctgcg ccccaacgaa agaacggcgc
    18241 aggtctggag ggctggtttg gagcaggact acgtcgccgg agacgatgat gagagcggca
    18301 ccttcaacgt cagcggggtg ctgatcgcca ccgatcagcg cctgatattc gtgcaggaga
    18361 agggagtgtt cggaaagagc tacaagcccc tggagagcat ggagtaccgg gagatagtca
    18421 actggaagct cgggcagacc atgcgcataa agtcattgca ggtcgacgta tcccagggcc
    18481 gccaccggcg taaggtgttc aacaacctca gcgaggtgga ccccatgacc ctcagcgtca
    18541 tcgcgccttg gaccctggac caggtgaaac agctgctggg caatctgaag agcgccgctc
    18601 cctgagcttc ttcagggacc gacgtccttc aacagcctct tccggacctc ggcctgcttg
    18661 gccatggtcc tggcgaacac cagatcgaag atcgccggaa gcacgtcctc cagcaccagc
    18721 agcccctgct cggtgatccc acctttcgtg gccaccttct ccttgagcga ggccactgac
    18781 tccccggaac ccaacgccag cgccgtcccc tgcatggtct ccaggaccat atcccaggcc
    18841 tcctttcggt ccataccctg gcgaacgccc gcttccgcga actgatgcat catctccgcc
    18901 agcagggcgg gaccacaact ggtcaggtcc gtggccacat ccaacccgtc ctcctggacc
    18961 acccggacct tcgaggcgcg tgccaggacc ttctccagcg acgaggcttg cgacctcgtt
    19021 accgacggtc cgtgagatac gagcgatacg ccgcgtccgc gctccatggt caccgagggt
    19081 atcagcttgc tcatcggggt cttgcagacg ccctccagaa cggcgagggg caacgaaccg
    19141 ttgaccacca ccacgtgggc gtatggcccg gcggacgata cctccctcag cacgcccaac
    19201 agctgatcgc tgcgcacggc cacgaacagc acgtcgctgc ctttggcggc cttgacgttg
    19261 ctctcggcca cgctaactcc gggaaatctc ccggcgaagg atacggcctt ggacgggccg
    19321 cggttggcga ccacggtgtt ctctggagat atcgctccgc tatccagcaa tcccgctgcc
    19381 agcgatgagc ccatgttgcc gagaccgatg aaaccgattt tcaaatgaag accgtccggc
    19441 atcggtgagg cgccgcggcg ataaaataat agcgattctc agaggcctag ctcgtccgat
    19501 ctcaatttca ttccctcgag cgccaccgac aggaactcgt ccctcggaat gctcaatcgc
    19561 tcgcagacca ttatgcggtc ccggtcaacg ccacgggcga agtccctgtt gccgaacttt
    19621 ttggcgatgg agctgacctt cacgtcagcc agcttctttg acggcaggac cagggcgcag
    19681 gcgatgacca ggccggacac ggcgtcggcg gccagcagcc ccctcttcag ccggtcatcc
    19741 actggaaccc cggtcgcttc gtgattgtga gcgagtatgg cctgcaccac ttcgttcggc
    19801 accttgccct gcaggatgtc ccgggcgatc agggcgtggt cctgcatccc gtggcactcc
    19861 tcgaagtcga tatcatgcag tatgccggtc acctcccata gctcaagatc ttctcccaga
    19921 tgcacggccg cttgcctcat gaccgccccg acggctacca tgtgcttgag gttgctctct
    19981 ttgctaacgt gacctctgac cagctccaac gcctctgctc tatccatgtc gccatcgccc
    20041 gtgaacggaa ctatttgcag atgccagttc agactatcag tctaccggcg gagggacccc
    20101 acatggcgtc gtacaccgct tccaccttga ccaccaccgc ggccttggcc ggaagcttgg
    20161 ggttaacccc ttgcacccat ttgcgcatct cgtcgaacat cggtccggcc ttgtacacct
    20221 tggcggaacc tttgatctgg taggatttct tggtgtcagt gtcgtaacac agaatggaga
    20281 tacgcgggtt ctcggaaaga ttggcggcgg tcttcaagaa gaagttgtca accagcaaca
    20341 gtgattcatc gtcgatgatc ttcattagcc ctacgaagac cacgttgggg gtaccgtccc
    20401 tggtggccgt ggcgataggg atgggcttct gtttggctag tgcctctttt acctcggtcg
    20461 gcatcttgac catttatatc accataataa gaactaattg cagccttaat aaaactaagc
    20521 actgcccatt cgtctaatga agagataagt agtgaaaggg taaaatgaag gtcagaccat
    20581 catcatcgta tgagcaacaa ggaggccgtg atcatggtgg gccgtctgat ggaactggcg
    20641 gcccggaccg cgcccaaggc catgggcaag gatctcatcg agaccgcgct gctcaccgac
    20701 gagcagaggg tgaagttagg agaggacctc atcgcggtgg gcaaggaacg aggcttaccc
    20761 ggttaccaga gggacgggca gaacgtcctg gactcggatg ccgtggtcct catcgggctg
    20821 ctgccgcacc tgggcgtggg attggattgc ggagcctgcg gcgtctcggg atgcgcggag
    20881 ttcaacgtgc tttcggccag caaggacttc cagggaccga actgcgcctt acgtttgttg
    20941 gacatgggca tcgccctcgg ctcggccgcc aaggtggcct ccgaccacaa tgtggataac
    21001 cgcataatgt accgcatcgg ggtgtcggcg atacggctcg gctactcccg ttccaacatc
    21061 tgccacggca taccgctttc ggtcaccggt aagaacatct tcttcgaccg gggaaaatga
    21121 tcacttcggc cggaagtcct ttccgacctt gaaggcctcg gccaccgtct tgcctttggt
    21181 gaagtagagc ccgccggaac tgaggtacat gagcagttgg agcttgtcca tgtccgggac
    21241 gccgcccgtc aaacggctct cgtccacgta cacctcctcc acctctccga tcacgatgtc
    21301 cgttccttcg agctcgatta tctcgtccag gatgagctcg atgttgaccg ggcattccct
    21361 ggccatgggt gcggtgagcg tcttcccgaa gaacacatcg aacacgttgg acttgtcctc
    21421 ctggtaaccg gagaccagtc cgcagtggtc ggcggcggct gccgtaccga cgtcgggcag
    21481 gttgatgctg aaggtccggt tctcccgaat gccgtccttg gtccggcggt ccttgcccat
    21541 caccaccgcc atcttcggcg gctcgtcatc gatcatggtg gcccaggcga tggtgcagaa
    21601 gttgaccttg ccctgcacct tagctcccac taccaccact ggcaatccca tcatgggcag
    21661 tgtccgtccc aacgtcctct tggtcatttt tatcgcctga gcatcgtgtt cgatgaatat
    21721 caagggtgag gcgcccgttc ttaaaagcgg ttcggaccgc gtaacgcata aatacttcca
    21781 tgctatgaca tgacatagca cggtaatagt gcttaagaca aaggaggata ggaaatggcc
    21841 gaagcgaaga aacaagacct gccgttcgcg gcagatgccc tgcacaccac cgctctggcg
    21901 acgccgttca tcgtcgcctt taatgagggc gaggcaggct actacggcct ttcccatgag
    21961 atccagagga tcggcaggtc ctgcctgacc cccggcgcca gggtggtcga ccttcgctgc
    22021 gacctgaacc tcgtgatgcc tatcatcgag gagaacgagg acctctgccg gttcaccttg
    22081 ctctccccgg acgagaggag cggtttccga tgcttcgata aattgcgcac cagggtgcgg
    22141 ctggggttcg tggacgctgc ccaactggac ctgaacgagg gtttcccgga ggtgtccgcc
    22201 cggatggtcc tggccatcgg tgcgttaggc ggactgtcgg aaaggagacg gacggaggtc
    22261 gccgattcga tgcaccgccg gatggagagg aacggcgtcg gagtgataat ggaggtcgtc
    22321 gagaccgatg tcgcgccggg cctgcgccgc aagagacctt tgtggtcggc ggcagagtgg
    22381 gaatccctgt tcaagaatgc cggattccgc agcgttcaga ggctgtggac cgacggggag
    22441 cggatggcct ggaccgttaa aaaatgaaaa ggaaagaggg ggcgtggacc ccctcgaaat
    22501 aatttttcgc tcagtccttc agcaggtcgt agattatcgc ggcgagcgcg gcaccgacca
    22561 tgggggcggc gatgaatatc cagagctgct cgatagccca tcctccctgg aacagagccg
    22621 gaccgatgga acgggccggg ttgaccgagg tgttgtccac cggtatggat atcaggtgta
    22681 tcagcgccag cacgataccg atcgggatgc ccgcgaaacc ggcggcggcc ttcttgtcgg
    22741 tggtgaacag aacggtcagc atcaggaggg ccgtgagaac gacctcgatg atcatgaccg
    22801 cgccgagctc aaagccgcca ggggagtggt ccccataacc gttggagcca aagccgctgg
    22861 cggccgcgtc gaaacccggg ccgccgctgg ccacgatgaa cagtataccg gcggccagaa
    22921 tggcgccgat gacctgcgcg accatgtaga acagcgcctc cttgcctccg atcttcttgg
    22981 acatgaacat gcccaaggtg accgcggggt tgatgtggca cccggatatc ggtccaatgg
    23041 cataggccat gaccagcagc gtgaaaccga aggctaacgc cacgcccaag gccccgaccc
    23101 aagagccagc cagaactgcg gtaccgacac cgccgaagac cagcacgaag gtcccgatca
    23161 tctcagcaac aagtttcttc atgacagatt tgtccataat atgaacctcg cccgtccagg
    23221 gatttctaaa ttatatatca ttaatgcttg aaaaaacaga tatggcctag taaggcggaa
    23281 caagacctag tgcgagcaac tagccgatgg tgcagcccgg accttcgccc atgcggaaca
    23341 gcggtgaact tcttgaaccg gtgtcgttca agcggtgcat gatgtccagg atcaggatgg
    23401 aatggtccga gatgcctgac acacgttcct gatgggagta cttggcccat aatggatgtt
    23461 ggatctgcgg ggacgctagc ccatggtcgg tcctcatccc cttgccggag gaggagtacc
    23521 atgaatattc ccgggccacc tggtgatatt ccctccagac gtcccgccag cccaggtcca
    23581 gcaatgcgga tagatgctcc gtgcctagaa agggagtccc ttctgaatcc cgctccagac
    23641 cggtgctgag gtcccctatg atcatgcggc ggtccttgag gtccacggac tccttggcga
    23701 actccaacag ggcctgccag aactccatct ttccgggcag gtcggacgcc cctggcacgt
    23761 gcaccgccag gatgcgcagg tcggaacctt ccggagagac ctccatccag cgatgcggag
    23821 acgataaggt ccttcccccg ggaagctgga ccagggcgga cttggaggcg accaatatgc
    23881 cgttggtgcg cggaggaggc tgggaattca agatgtaggg atagcccagg gcggccaagg
    23941 agagagagac ctcgatgatc ctctccggtc tgaactccag cagaaccagt atgtccgggt
    24001 cgtgccgacg tacggcctcg actataccgg gcaggcgctc ctgggcgccc ccgtactgca
    24061 ggttccattc cataattcgc atcggccagg ccaaatcgtc acctggatta gatgaacctt
    24121 gccctttggc ccgttcggtc gaacgaacgt ttgaagtaac ggtccgggca tatcgtatta
    24181 ctttttcaat atctattaat actgagtaat actattttga taattagtgt tacggcttcg
    24241 gtccgcccct tgcaatacga acatcatccc agccattatc atcctcctat ggacgccgga
    24301 tggaccgagg ccttatcacg gagcttggga gcgaatcgat taactaggtt cgttggaatt
    24361 acccaatcat ggtgaagggg cacagcgcgt cgagctttcg tttccgcctg aacaacggcg
    24421 ttgaggttcc ggccctgggg ttggggacct acaagctgcc gggggagcag gcctacgcgc
    24481 cagtccgcat ggccctggac tgtggatacc ggcacatcga taccgcctcc ttctatgaga
    24541 acgaggaggn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    24601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt tcaccgtccg
    24661 ccacctgcag gagctgtaca gcgcctgcca ggtcatgccc gccgtcaatc aggtggagat
    24721 gagccccttc ctttttcaaa aagatcttct ggagcattgc caggtacgcg atatattggt
    24781 cacggcttac tcaccgttag ggcgtgggca ggtgctcgcg gaccccgtgc tcaaggaggt
    24841 gggcgataga catcgcaaga ccccggcgca gatcatcttg agatggtgcc tgcagaaagg
    24901 catggcgacc atcccccgct ccgctgacat cggccatatc caacagaact cccagatatt
    24961 caacttcgac ctggacgggg aggacatggc caggttggac cttctgcatt ccgggctgcg
    25021 caccaccacc gacccggaca ccttcgagtg agacggcaaa gcattaagtc atggcgcggc
    25081 ggatggagtg ccgatgaccg agcaggtccc caagatcgcc atctacctgg actttgagaa
    25141 tttggcaata tccgccaagg aagtctatcc gtccaccccc agaccgctga ggatcgacga
    25201 tattctcgac tacgccaagg gctatggcga cgtactgatc aagaaggcct tcgccgattg
    25261 gaacaaacca ccctgcaacc agtacgtgga ggaccttcgt ctgcgagcct tcgacctgat
    25321 cttcttgccg cagacctccc tgtcgggaaa gaacggtgcc gacctgcgca tgaccatcga
    25381 cgccctggag gacatgtacg acaaggacct tctggacgtc ttcttcctag ggaccggcga
    25441 caccgacttc attcacctgg tccgcaagct caaggagcgg ggcaaggagg tcgtggtcct
    25501 ggggttcgag cattcggtcg gacggaccat acgctataac tgcgaccgct tcgagtccct
    25561 ggaggacctg ttgggcaaac ctccggcgcc ggcggccaag gagaagaagg aggaggagga
    25621 actggaggac gatccccgcg agctcttcat ccgctatgtg aagaaccgtt ccacggacga
    25681 accggcgata ttgtcgcaga taaagaacga cctgatgcgc ctggacccct cgttctcgga
    25741 gaagaagtac ggatacaagc atttcaagga ctttctggag accttccgtg gagacctttt
    25801 caccaacatc aagatggacg acaaggccgg gcatcacctg gttttcttca agagctattc
    25861 cgaactgacg tcggacatca acgaggcaca ggtgcgggac ttcatcgaga aggacatgcg
    25921 tttcctaaag gaccgcaacc tgcgcaaggc gctgtacaag gagatagtga accttttcca
    25981 tgcggacggg gagacgacca tcaaccagat gatcgatgac ctctggtcac tgttcgacaa
    26041 gaaggtgccc aaggccacct tgaaacgctt cctgcgcacc atggccgaag gtcggatgtt
    26101 caagttcgcc gcggtgaagt acaccggcaa catctatacc atgccccagg tgctgaaggc
    26161 cgacctgccg tccatggaga agctggacga tatctacgta cagcgcataa tcgacctgac
    26221 cctgaagaag tactcaggag tgcctcaaga gacggtcacc aagctaatgg ggctcagctg
    26281 acgatacggc acctatcgta tggcctggtg gcgtccgatg accttgcggg cgaagcgtcc
    26341 gaaccttgcc ctggttcagg ttgagctgtc gccgttcgaa gatctttggc cttttaagag
    26401 ggcggccgtc ataccctccc ggtccaggcg gaagaaggtc cagtccatct ttcgcccccc
    26461 ttgtttttcg tagaatctca tggctccaac gttccagttc aaggcgcacc attccatgcg
    26521 gccgcatccc cggtcgatgg cctcttggac gcagaacttg aacagttcgc gtcccacccc
    26581 gctctggcgt gcgctctcct gaacgtatat gtcctccagg aacagagtgg gcgtggccag
    26641 gaacgtggag taggtgaaat aataagtgat gtaaccgacc gcccttccgt caaaatatcc
    26701 caggaaggca tggaagagcg ccggatcgga tgtgacatgc tggagcagcc tttccctcgc
    26761 ctcggcggta ggcgggtcca gcttctcgaa caccgctagc tcggtgatca gggcgatcag
    26821 ctggtcagcg ctctccggcg ttacacggac gatctccact ttccttgagg ctccaggcat
    26881 gcctccgata acgcgctctc aatatttcgc tttcaccacc gttattctga tttttcagaa
    26941 tattcttata gttttaattg tcattcacag ttcatgcctc gccgcaggga tagcccgaaa
    27001 gaggaatgct gcaccggacc gaccgagcca cccaagtacg acgtggaggg ggtggccacg
    27061 gtggacgaga gagggcagat ggtgctgccc aaggccatcc gcgacaaggc cggcatccgt
    27121 ccgggggaca agctggctat cgtcaccctg gtcagggacg ggcgggtttg ctgcatccac
    27181 cttttccgga cggacgacct ggcgaacgga gtgaaggaca tcctagagcc cagggaggga
    27241 tgatccgtgg aggaaggata cgcgaaggag accttgacca ccgtccctca actgggaagc
    27301 aaggagcgca acgaccacct caaggccaga attggcttag accgcatggg gcaccgggta
    27361 cggccgggac tttatgccat aggagcgcct gagcgaacgt caccggtgct ggttaccgcg
    27421 aactataccc tcagcttcga cgccttgcgc tcgtcgctaa cgggaaggag cgtctggata
    27481 ctggtgctgg acaccaaggg aataaacgtc tggtgcgcgg ctggaaagag aaccttcggc
    27541 acggaggagc ttgtcaaagc ggtgcaggcc acgggattgg catcgaaagt ggaaggtcgg
    27601 acattgatcc tcccccagct gggagcgccc ggggtctccg cccatgcggt caagaaagac
    27661 tgcggcttca aggtggagta cggaccggtg cgggcggagg acctgcctgc atatctggac
    27721 actggtgaat gtacagagga aatgcgcacc gtccgcttca cgctaaagga ccgtctggtg
    27781 ctggcgccgg tggagatcag gaactaccgc tggtggatgc tattaatgat tctggcagcc
    27841 gtgttcgttc ccttctacgg gcctttggtt ctggccatga ccctgggcgg gatattcctg
    27901 ttcccggccc tgctgcctta ccttccgggt aaggacctgt cgttgaaagg gatcgtccta
    27961 ggcgtattac tggtcactcc cttcgccctg taccagctgc tattttggca cggaacgttc
    28021 gtgttcgcgg cggtggtcgc ggagtacctt ctgatagcag cctggctcgg gtatcttgga
    28081 ttgaacttca ccggatccac gaccttcacc tcgcgcaccg gggtgcgccg tgagatattc
    28141 acctacatcc taccgatggc ggtaatggcg atactgggcg ggatagcggt cgtttccagc
    28201 ctcgtgctct acgcggggtg gttatgatgg agatcgggat gctggaccta cagcccccgg
    28261 aaaagggcaa ggcgctgaac accctggtct ttcatcctgg gcgatgcatc aactgcggca
    28321 tgtgcctgaa ggtctgtccg catagggtct tcgccccggg cgaaagaagg gtgagactgg
    28381 tcaaggcgga ggcctgcatg gaatgcgggg cctgccagat gaactgcccg gcggaagcca
    28441 tcaaagtgga cagcggagtg ggatgcgccg cggccatgat aagggcggcc ctgaaaggaa
    28501 aggacggcga ggagtgcgga gaggaatgct gccgatgagc ggtcattgag ctagcggcca
    28561 cttccaggtg aaccatccgg atggcacctt gatcacgaac cgggcgccct ttcccggctc
    28621 tcccccctcg gcgatggtga agccggtggt ggccaatatc tctctggcca ggtatagccc
    28681 gagaccggtg ttctctccgt agcccttgtc gaagatcatc tcctttttgt ccgccggtac
    28741 cccgatgccg tcgtcctccc agattatgga gaggccggtc tcggtgttct ctccccggac
    28801 gaccaccttg gtgacccgtt ccccgtgccg caccgtgttg tccgccagag tatggaagac
    28861 gttctccagc agcgggtcgg ccagaagccg tataccttcc actcgggatt cgacggcgat
    28921 cccgtccatg tccaccttgc ccagtacctt gttcactgta gaatggacct cctgccaggc
    28981 agtggcgctc attcccaacg agctctgcgc gctggcgaaa tccaggtggt cattggcgct
    29041 cctggcccgt tccatgatct tttccataag gtgcctttgc ctctcgttca gctccgttcc
    29101 ttccaaaagc cccaggtaac cccagctggc cgtcaggtcg ttcctgatgt cgtgcctgag
    29161 tatctggttg agcgtgctca tgctccggtt ggcccgccgg aggtcctctt ccagggcctt
    29221 ccggttggtt atgtcgtgca gtacgagcac cgcgccgacc ggctttccct cccggaatat
    29281 gtcagaggtg gtaaggacga aatgcctggc gttcccatcg atgatcatgg ccgtctccca
    29341 tttgttggag ccagcgggga ccttcagccc gcgagccttc atcctccccc agaggtaatc
    29401 cgagttctgg tccaggacct tctggccttg cttgttggcg tagaccacct gcagggagga
    29461 atccaagatt ataaccgcat cgtccatgcc cccgatcgct tcccggaagc gaattatctc
    29521 caggttcacg aaatccgagc gtctttctcc gacgaacacg atcagcgcgg cgagcgtgta
    29581 ccctatcgac aatatgtcga tcaggggatc gtcacggggg ctgaacacgt acaacaggcc
    29641 actgaacaat atggtcagag tggccagcat gatgatcccc agcccggccc ggcgttcggg
    29701 aagcgtctcc aggaacgccc tggccagcaa aatgttggtg atcaggatga ccgagatcat
    29761 ataacccatc cagatcacga acagcgggcc gtactcggcc tcgaacatgt agaacccgtg
    29821 gctctggatg atgatgacgt cgcgatagaa aaggtggtgc agaccgttgg tcgagttcag
    29881 gaggacggac aggatggccg ggaaggcgat cagcagcaaa tttcgcctgg tgatgtatct
    29941 ccccagtcct atgtactgaa tgacgaagat gagcagggag atgatgatca tcgacccaca
    30001 caagtactcc agcacgacca ccgccagcac taggtccagg tctccgatca gcttctctgc
    30061 cagaagcacc atgaagttca acgagacgaa ggcgaagcag atggccatgg ccgtgcggtg
    30121 ctcggtctcc ttccctttca ggaccttgta ggccaccccg gcggtgaacg ctgccgcaag
    30181 aagattgggt acgatcacga tagccccata gtattccatg gtcgacctgg caggggagaa
    30241 tattcctgga accgatataa gtgatgtggg ggacgattat catggatgac agaagcgcct
    30301 tccctaagaa gcgccccctt ccttatgctg ggcgtccttg gccgaccctt tcatgacctg
    30361 gtcctcgata tggagcaccg acccggacaa cgtgtaggcc agcgtgatga atatcatcgg
    30421 taccccggcg accagatacc agatgcggac gccgaacgcg tcggccaatg gaccggccag
    30481 taaaagtccg accggcatca tggcggtcgc cccggcgcta atcaaggcga acaccctgcc
    30541 ctgcatggcg aaggggacgg acgcctgcat catggccatc atggaaccgt taagcagcga
    30601 gatgctgagg ccgaccgctg ccgatagccc ataggccagc aggatgacct cggccggaac
    30661 gatccccagg gcggtcatgg ccaggctaag caccatcgtg gagaccagca tggtgatgat
    30721 cttgcgcttg cctcctcccc aaacccccaa gagcacaccc cccgccagca ttccgatgcc
    30781 ggccagggcc tccatcgccg cgtactcgcc ggcacctcct cggaagtggt caatgaccag
    30841 cagtggcagc agggaaaagg ccgggctgag cagaagattg gctatcatga acaggaacat
    30901 tatagacaga gcgccgcgcc agctcttcag gaaggccaac ccctccttca tctcgttcat
    30961 gagggacgct ttttccttta cgcccctatc cggctcgggc acgtggatga acatcaatgg
    31021 aacgatagcg atcacagccg tgatcaggtc gaccgacagc accgcccaca tcgggaacag
    31081 cgctatcatc accgccccgg ccggggcggc gatcacgctg gaaagaccga acatggcctg
    31141 atttagcccg cccacccttc ccaagtgacg ctcgggcacc atcaacgagg tggcggcctg
    31201 catggccggc caatggaacc cggatacggt ggcccgaccg aacatggcca ggagaaccat
    31261 ccagacctcc gccgttccgg ccaggaaggc cagcatgagc agcagggcca taagcgatat
    31321 tagggaatcc gccgcgatca tcgtccggcg gcggttccag cggtcgacgt aggctccggc
    31381 ccagggagcg accaggacct gcgggagaac tcccatcagc gttcccaggg ccagcacggt
    31441 cgccgaaccg gtctccaccg tcagccacca gaccagggcg aactggacca gggcgctccc
    31501 gaccagggag aaggactgcc ctccccagat ggtaaagaag ctcctcttcc aagaattccc
    31561 ctcgccgctc gttcgcatca tgcacctttc atcggtggcc accgaccatc aaccacgtgg
    31621 acacaagtga ccgccctccc cgtttcccac cgagggcgag aattctcttt ttgagatata
    31681 atgcttgatt gatgatttcg tatggcgaga acgttagcga ccgccgccgt tcatttattt
    31741 acaagctaat tcaatcctct ggacggtcat gaccttgcgc cttttatgct ggaacgtcaa
    31801 cgggatccgg gcggcctaca agaaagatct gaatggattg ctagagcggg acggggcgga
    31861 catcatctgc ctgcaggaga ccaaggccac cgtggaccag ttgccggatg gattgcgtaa
    31921 cgctccagga taccattcct atttcgtttc gccggaggag aagaagggct acagcggggt
    31981 gggcatctat tcgaaggtgg aaccgaacaa ggtgatacct ggcttcggac agaggcgctt
    32041 cgattccgag ggccggaccc tggtggccca tttcgatgag ttcgttctct tcaacatata
    32101 cttcccgaac ggaaaggcct ccccggaacg gctgcgatac aagatggagt tctaccagga
    32161 gttcctggag gtggccaagc gaaccgtgga gggcggaaag cacgtgatcg tgtgcgggga
    32221 cgtgaacacc gcgcaccggg agatcgatct ggcccgcccc aaggagaacg gtaaggtctc
    32281 cgggttcctg ccccaggaga gaagatggat agacgatttt ttggccgccg gtttcgtaga
    32341 cacgttccgc atgttcgatc cgagcccgga acgttacacc tggtgggaca tgaagacccg
    32401 ggccagggaa cggaacgtgg gatggcgcat agactacttc ttcgttgacg aagggctgag
    32461 gaacaggtgc cgaaacgcct tcatcctgcc cgaggtccag ggctcggacc actgcccgat
    32521 aggcctggag ctggagatat gagcgtcgtg atacgcagga tgcgttctga tgattatgcc
    32581 caggtcgtcg acatctggat aaggtccggg cttccctatc agccgcgggg cagggactcc
    32641 gaggagcggg tgcgggagca gctggagaag gattcgtcca tctacctggt ggccgaggac
    32701 cacggaaaag tggtcggggt ggtgctggtc acccacgacc tgcgaaaggg atggctgaac
    32761 cgtctagcgg ttcccccgga ggagcagggg aaggggatcg ccaaagagct ggtcagccgg
    32821 gcggaggagg atctctccac cctaggggtc aacatcttcg ccgtgcaggt ccatgagcat
    32881 aaccatcgct ctcggaagct gttcgccgag ctcggctacc aggagcatca tgacatcatt
    32941 tactgctcca agcggtatgg tccggacgag tgattggtgg cattgacaat tttatatctg
    33001 gcgaagcaca ttccgaggaa gaaggcacta aatgagcgtt gttctggcta ccgatggcag
    33061 gtcgcacacc tccaaagcga tcgattatgc tctggagtac gcgcggctgc acaaagaggc
    33121 tctgttcgtc gttttcgtaa taggcccgag gcacgaggag aaccgggagg gcaccgtggg
    33181 ggacgctaag aagcaccttg agcagatcaa agccagggcg acccagcagg gagtggagac
    33241 caccgttctc ctggagaccg gcgcgccggc cgaatcgacc atcgccgtgg ccgaaagggt
    33301 gaacgcctcg gtgataatcg tgggcacatc gggcaagacc gtcctggaca gggtacttat
    33361 cggcagcgtc tcggaccacg tggtgcacaa ctcgcactgc acggtcatcg tcgtcaagtg
    33421 atcagagacg acctagcgcc tccaacagcg ccaggacgac ggtacgtggg tgcggcgggc
    33481 aaccggggat gaacaggtcc actggcagag cttcggccac tccattcccc gcggcgtatg
    33541 tgccaccgaa cggaccgccc gatatggcgc aggtgcccat ggccaccacc aaacgtggct
    33601 caggtgcggc ccggtaggtc ttcatgagcg ccgggagcat gttccgggtg accggcccgg
    33661 tgaccaacag catgtcggca tgcctgggcg aggccacgat cttgatgccg aagcgctcca
    33721 ggtcgtatat cggattggat agggagttca cctccacctc gcaaccgttg caggaaccgg
    33781 catctaccat gcggatggcc agggacctgc ccagaacctt gcgtgcctcg tcccgcaatt
    33841 gaaccttcag ctcgggtagc ggtacgttcc ggaaaagcgt aaatgatgag cgctgagtta
    33901 ccgccgggac cttgaccgag aacgatatgg cgtcccgcgg acaggccggg aggcaatcgc
    33961 cacagaacag gcattttccg gcatccacgc tccaatcgcc ctgggtggag atggccgatg
    34021 ccggacagac ggggacgcat tctccgcata ggtcgcagcg ggcgtcggcc atgggtgcgc
    34081 gggtgtggcc ctgctgctgc aacaatcgca gcttttcggt gaccaccttc ttgtcccgga
    34141 ccctcctctc gatgatgtct agcatggtaa cccctacaga tcgttccccg cgtacgacag
    34201 gttgtagctc ttgttgatca gcgggaaatc cggcacgata ttgccgagta ccgccctctc
    34261 catggtcggc cagttgcaga acgatggatc gcgcaccttg taccggacta tatttccttc
    34321 tcggaagtga acgcagtgta ccagctcacc gcggggggcc tccaccagac cgaggccgaa
    34381 gccatccggt aacggcatct cggagcgaat ggctccctcg tggagatggt ccacacattg
    34441 cttgaccatg ctgatcgact cgcgcacctc ttcgaccttc accatgagcc tggccagaac
    34501 gtccccctcc cggcgcaccg gcaccaggaa gctcaggcgt ccataggcgc cgtaggggaa
    34561 gtccctcctg gtgtccctgt cccagccgga ggcccgggcc accggcccgg tcgcccgcag
    34621 gtccttggcc attggcagcg ccagcgtccc ggtcgtctcc acccggtcca ggaaggacgg
    34681 cgaccccaac aaggaatcca ccataggctc gaaggtcaga ccgagatcga ccatcgcccc
    34741 ttccagcagg tccctcctcc cctcgtccag gtcccgggcc gccccgccga tggcgatgga
    34801 tccccagagc agccggtgcc cggtgaggtt ggcgttcaaa cgtagcatgc gctccctgag
    34861 caccgaggcc tcggcggccg gcacggcgaa agccacgtcg gtggccatgc cccctatgtc
    34921 acccaaatgg ttgtagatac gctccagctc ggcgtagatg caacggagta gctgagccct
    34981 gtccggaacg gggttggcca tctccaccgc ctggcagaat gccagggcgt gcgccacgcc
    35041 gttgtccccg gagatcctct cgaccaggcg cagcgcgcgg ttaagtgtgc aaccctccag
    35101 cgacctctcg acgccccggt gaacgtatcc caggcgaacc tccaggttca atatcggctc
    35161 cccggcggtg gagaaacgga aatgcccagg ttcgatgacc ccggcgtgca ccggtccgac
    35221 cgggacctcc aatattccgt ccccctccac cctgcggtag tggtgcgcct ccccggtgaa
    35281 cggcaccttg gcccccttgt cgaaccccgg tgagagagga tgcacgtgcc gcggccattc
    35341 gtgcagatgc agcggccggg gatcgggatg gtccagaggc gtgatgccgc tcatctccat
    35401 catctcccgc tcgtaccagt tggccgccgg gacctccgtg gtaagagagg gatatccctc
    35461 cccttccagc tcgctctcta ggaccacgat gccgtggcgg gggaccagta ccagggccat
    35521 caccttgttg tcgctcggaa cgtagtaaag attggaaagc tcgccctcct ccttgcgcac
    35581 caggtgggaa accagcgggc gcaacaggtc gtccggtacg gccaggtgca gccgtccgtt
    35641 cctctcctcg tacccgaatg gcggaaacgg caaagaatcc agaagctcga cgttgtaata
    35701 cctcatgcgc tcaccccgaa cagttcgacc accgcggata gggcgtctga cacgacctcc
    35761 ggaaggaaca gccccagccc caatatcgcc aaggccagga agagcatcgg cagcaaacga
    35821 agctttccca gctccccttc gggcagccct tcctgcggtt ttccggagac catgccgaag
    35881 atgcggtagg tcatcccggc gaatattatg accaggagcg cgatgaagag cccggccacc
    35941 aggtaatcgc cctggaccag cgccccggag attatgaaca gctcgccgat gaatatggcg
    36001 aacggcggtg aaccggctat ggccgcccct cccagcacca gcagggcggc ggtggtcggc
    36061 atcgtcctcc ccagaccttt gatgtccttc atctcccggg tgcggtactt ttggatcacg
    36121 ttcccggcac cgaagaacat cagggtcttg gtgagagaat gcgccagcac atggaacacc
    36181 gctccgaaca cggccagcgg cccgcctatt ccgaagccta gcgctattat gcccatgtgt
    36241 tccacgctgg agaaggccag gaaccgcttg acgtccctgg acgtcaatat gaaggcggtg
    36301 gcgatggcca atgacaatag accgaagaaa atcagcagcg acgaggagaa tcccggcacc
    36361 gcttcattgg ccaggatgtg caccctcagc acgccgtaca tggcgcagtt cagcaggacg
    36421 gcggaaagca gggcgctgat tggcgtcggg gcctggctgt gagcgtccgg cagccaggta
    36481 tgcatgggcg ccagcccggc cttggtgccc agtcctacca ggatgaagat gaaagatatt
    36541 ttaagcaggg cggggtccag ctgtccggcc accgaacgaa gcaccgacca gtccagggtg
    36601 tcggcgttag cgcccagcgc atccacggac gaggcgtaca ggagtatgat gcccagcagg
    36661 gcgagggtta tccccacgga acagattatc agatacttcc aggaagcctc catggcctcg
    36721 ctcttcttgt agaagccgac caggaaggcc gagaccaggg tggtcccttc cacggcgatc
    36781 cacatgaggc ctagggagtc caccaccacc acgacgagca tgctgaaggc gaagaggtgc
    36841 aggagcgcgt ggtagtagcg caggtccttg atgttgatct cgccctccgt gcggtcgtgc
    36901 ttcagatact ccactgagta caggctcacc agggcggtta tgaccacgat gacgaccatg
    36961 aagagaccgg acagcgggtc caggtaccac agaccggtat cgacggggcc ttcgaagaag
    37021 gcctggtagc agtaggggat cgccaccagg gcggtgatca gcgagccggc cacgctgaac
    37081 acgaagatag ccctctcgct acgggatata gcgcacagca aggcggtgat cagcgggacc
    37141 agcaacagaa tctcgaccat gttaacccct cagcctcctc aggaaggtgg tgtcgagcgt
    37201 ctcgaaggtc tggttgatgc ggtaggcgaa tatgcccatg atcagcacgg ccatgaacac
    37261 gtcgaagaat atgcctatct ccacgatgag cggcatgcca taggtggtgg agatgatgcc
    37321 caggaaaagc ccgttctcca tcatcagcag acctaccatc tgggtcatgg ccttgcgccg
    37381 gctgatcatc atgaacatgc cgatgaacac caccgccaag gatatggcca ggcagttgcg
    37441 ggtgaccgct tccgccgagg agatgagcgg ttcggtcacg taataggcca cgatcaccaa
    37501 acctccggag atgagcagcg aggccggtat gcccaccagc ggctcgatct cccggtgcac
    37561 cttgaggcgg tctatcgagt acatcaggaa gcgcgggatt atgatgccct tgacgaccag
    37621 ggtcagggcg gccacgatat agatgtgctc cgagccggta taatgcgcca ggaccaccga
    37681 tatggccgcc agcatgatag actggatggc gaaggagcgt accagctgcc ccatccgggt
    37741 gctggccatg accagcaagg acaccaacaa tatggccgcc gccaggaagt ttatggtgtc
    37801 tatgctcaga aggtcgacca tgctctcacc tcacagaatg taataggaca tcaccgccag
    37861 cagggacaac gtgaaagata tcgtcagcag gttgggcagc cggaacaggc gcatcttggc
    37921 catgaccgac tccaccaatg ccacgcttat agcgagcacc aggagcttca gggcgatgga
    37981 cccgaccccg agcgccagct cgcccgcctc catgcccagg gcgatccccc aggggaagaa
    38041 gacgttgctc agtattacca tgaacatggt cagccgaaca taggaggcca tgtccatcaa
    38101 cgccagctcc ctgccggaat actcgagcag catgccttcg tggaccatgg tcagctccag
    38161 atgggtggcc gggttgtcaa agggcacccg ggagttctcg gccatgagcg atatgaatat
    38221 ggcggccgag gccaggaaca gggtgggcga aataccgctg agcccttgtc cggcgaagtg
    38281 agcggatatc gccgataggt cggtggtgcc cgagatggcg gccaccgaga agatggacaa
    38341 tagcaacgta ggttccacga tggccgatat catgagctcc cggctgctgc ccatgcctcc
    38401 gaacgagctt cccccttcga gaccgccgag caccatcatg aaacggaaga gacctaggat
    38461 gtagatcacc gccaccatgt cccccacccc tccggagggg ccggtggtga acaccggtac
    38521 catcatcgcc aggcagacca tggcccccaa gcaaacatag gggatgatga ggaacagcca
    38581 ggaggcctcc ttagagacca cggtggattt gtgcagcagc ttccatatgt cgcggtacgg
    38641 ctgcaggacg ctcggtccct gacggcactg catccaggat ttgaccttcc ggatcacccc
    38701 ggcgagcagg ggcgaggaca ggaggatgaa cagcacctcc gccaggttca gaagaaggtc
    38761 gctcagttgc atgtcctcac ctcaacacca ccagtaatac gatcaggatg atcatcaggt
    38821 aggccaggta ggcctgtatg cttccgctct gcattcgctt cacgcgcatg gcgacagcga
    38881 cggtggcggc gaccaagggt tggtagatgt gggccgtgaa catctcggga agcgcctgct
    38941 cgaagcgcac cgtgcggata tagatggagg ggtgcggctc ttccttcacc tccgtgtgcg
    39001 gacggtagac ctgcttgaac actcgcatca aaggttggga aaaaccagtt ggagtgtact
    39061 gggtccggcg gtccagggtc gttccgcagt cccaggtgtc gcctaggacc acctttcttt
    39121 ttccggtcgc ccgcaggacc aggaaaacga ccagtatcgc cccggccagg agggcgctga
    39181 gaccgagcgg gttcagcccg ccctggtgca ggaagttgat gctgtacccc tcgatgacct
    39241 gtatgccggt ggccccgacc agcggagaga cggcggaggt cagctcttcg agaaggggga
    39301 aggaggcaac ccccagcaag aggcatagag cggccaaggg gaccagtggg aaaatctcca
    39361 cccggtccag cggccgcggc cgggcggccc cgttggagcg gggacgacct aggaaagtga
    39421 agccgaagag gcgcaggtag gccgcggcgg ctattgccgt gcacagggcc atgaccgcga
    39481 tggccagtgg taacgcgata cgtataagtg gatcggctat cggctcggcg tgcatcaggg
    39541 acttgaacat ggcccattcc gagacgaagc ccgagaaggg cggcaatgcg gccaccgcaa
    39601 gcgttccgaa caggaagacg gcggagaggc cgggcatggt cctggccaga ccgcctagtt
    39661 tctccaggtc ccattcccca gccgcccggc ggacggtacc tacgcccatc agcaacagcg
    39721 acttgaacac ggtatgattg ataagatgga acatggcggc cattatggcg aacgccgccg
    39781 gctccgccgc tccgtaggac tggaagagca tggccgcgcc gatggtaagc agtatcagcc
    39841 ccatgttctc catgctggag aaggccagaa cgcgcgaacc gtccctttgc accagagcct
    39901 gccaagcagc ccagagggcg gtggtggcgg ccattcccat gaccagcagc gacagcatgt
    39961 gctggtcccc caccccgacc atatcgaaaa tgatgcggac cagcacgaga acggccacgt
    40021 tggaagcggc cgtggagagc aaggcggtga tggtggaggg tgaccggctg tacaggtcag
    40081 gcatccagat atgtaacggc aatatcccca gcttgcttcc gaaacccagg aatgccagga
    40141 ggatgaccac ggcggacgtt aagggaccga gcgttgcgga taggccatgc atctcgctca
    40201 gacggacctc gcccgaggtt gtggacagaa agaccagagc gacgatgatc agggccgccc
    40261 cgaaatgggt caccgccaga tacttccagc cggcagcggt gtcctggtcc tcgcgggaac
    40321 cccaggcgcc caggaaggag gtcagggacg tggcctccca ggccaccaga agcaggagca
    40381 agtgatcggc caccatggcc aggaggaccg agagcatgaa gaggttgaat atcgaggccc
    40441 cccgggaggt tatcccttcc ctggagaaga gggagtacat ggccacgcag gcgaaggtaa
    40501 gcgaggttat gaggagcacg agcgcgccca gcgcatcgag gcggatggcg tagtcgccca
    40561 tggccgacgg gacgtcgagg acgaacgtgg acgttccgtt cagaagtacg agcaaggacc
    40621 agaaggcggc gctcaccgcc gaggccgccg agcaaaggta gctgtaaacc cgatgctttt
    40681 cgctcctcag taggagcgcc aacgctgtac ccagcaaggg cagggacagc atcagggcgg
    40741 gcaatacggc tgacaacatt tacaaggcct caatgaacta aggacgannn nnnnnnnnnn
    40801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    40861 nnnnnnnnnn nnnnnnnnnn nnnnnnntca aggccctgga ggtcggcatc caggtcgaga
    40921 tatcatcggt gaagatgtac cgcggagcgg ccctgatggt cgaggagccg ggggtgaggc
    40981 gccttctgga gaagctcgct tcgatcgagg aaggccaccg caagctgttg gaagagagca
    41041 tgcaattgct gcgtgacaaa ggcgcgtggt acggatactc cccgatcttg gagggttgat
    41101 ggttcggaga gggctcacca acataataat tcagtaacaa atatttttat ttctgacccc
    41161 ctttggccat cacgatggat gagctgaaaa aactttaata ccgggtgggc atgcatagag
    41221 cacaatctaa acggggttgg gcattggtcc accctcctca cttgggctca gaggtatcgc
    41281 aatggtcaaa ttaccgaaca tcgacagaga ggttcaagct tgccttcaat gcggctactg
    41341 cattcgcacc tgcgagacgt ggaggcagac gccctgggag tcggttaccc ccaggggcaa
    41401 gatcttctac atttcgcagc tgggcaagcg aaccgccata gacaagatgt tgggccgcaa
    41461 ggtcgagatc gatgatgagt tcgttgaagc gctattcatg tgcaccacct gcgccgcctg
    41521 cgccaccgtg tgccatgtcg ggatcgactt cgctgagttc tgggagaagg tcagggagtg
    41581 gtgcatcgac aacggccacg gccccatgcc cgcccacgtc actataaggg agcgcctgga
    41641 ggaaggtcgg aacccctaca acgagccgat ggacaagagg ggtgcctggt atcccgccgt
    41701 gccgaaagcg gacaacccgg acgtggtctt cttcgccggt tgcaccgctt cgtaccgcat
    41761 gcagaacctg gccaagtcca gcgtgatatt cctgaaccgc tgcggggtct ccaccaacat
    41821 aatggagggt gacgagtggt gctgcacctc tcccgccctc aggaccggcc agaccggact
    41881 gacctaccgc ttcgcggagc acacgatcag cacggtcgag cacatgggcg ccaaggccat
    41941 ggtcaccgcc tgcgccggct gctacaagac caccgtgcat gactacggaa agttctattc
    42001 ccaccccacg ttcgaggtct tccacttcgc ccagtacgcc aacaagctgc tgaaggagaa
    42061 gaaggtcaag tacaccaagg agctcaaggc caaggtcacc taccacgacc cgtgccacct
    42121 gggacggcat gccaaggtgt acgacgagcc gcgcgaggta ataaagtcca taccgggcgt
    42181 ggagttcatc gagatgaaga acatccgcga gaactcccgc tgctgcggag ccggtggcgg
    42241 ctacaagagc caatacaacg acatggccat cgccatagcc gtggagaggg tcaaggaggc
    42301 cgtggccacc ggcgccgaca tactggccac cacctgcccg ttctgcgtgc tgaacatgac
    42361 ccaggcggcc aagaagatcg gggccaagat aaaggtcatg gacgtctccg agatgctggt
    42421 catggccacc gagcccgagg ctccggtcga g
//
LOCUS       DAOPZI010000011        39853 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_877_length_39853_cov_8.427785, whole genome shotgun sequence.
ACCESSION   DAOPZI010000011 DAOPZI010000000
VERSION     DAOPZI010000011.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 39853)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 39853)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39853
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_877_length_39853_cov_8.427785"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..233)
                     /locus_tag="PKM11_03570"
     CDS             complement(<1..233)
                     /locus_tag="PKM11_03570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavoprotein"
                     /protein_id="HNX47618.1"
                     /translation="MKTVVAITGASGIVYGIRLLEELEGEKALIITETAKRILEAETA
                     YTVEQVLQLADEVYHEDELFAPVASGSHRFDAM"
     gene            481..903
                     /locus_tag="PKM11_03575"
     CDS             481..903
                     /locus_tag="PKM11_03575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19e"
                     /protein_id="HNX47619.1"
                     /translation="MVTVYDAPSDKLIANVAQKLKDSGSVSPPEWAEFAKTGVHTEKA
                     PIQVDWWYTRAASVLRKVYIKGPIGTSKLAAEYGGFNDRGSRPNRAVKGSRSIIRKSL
                     MQLESAGLVVRNKNNGRVVTPKGQALLDNAAKEVVDSN"
     gene            912..1247
                     /locus_tag="PKM11_03580"
     CDS             912..1247
                     /locus_tag="PKM11_03580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HNX47620.1"
                     /translation="MFVDDADLMELRRRKMADMQRQGEQQAAMEQQAQAMEVQRQAIL
                     RQILTTEARDRLANVRMAYPDVARSVEDQLIRLAQNGQINSQIDEPTLKQILRKVSPQ
                     KREINIERK"
     gene            1249..1404
                     /locus_tag="PKM11_03585"
     CDS             1249..1404
                     /locus_tag="PKM11_03585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L39e"
                     /protein_id="HNX47621.1"
                     /translation="MARNKHSAMKARLMKKVKQNRRVPAWVMMRTDRAFLRHPMRRNW
                     RHSKLKE"
     gene            1410..1676
                     /locus_tag="PKM11_03590"
     CDS             1410..1676
                     /locus_tag="PKM11_03590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31e"
                     /protein_id="HNX47622.1"
                     /translation="MAEENEKVYIIPLIKTKMVPTPGRSDRAIKEIRAYIARHMKTDE
                     KQVWIDPKVNESIWAHGKTAPPSKVRVKAVRFEDGLVEVSIPTE"
     gene            1687..2346
                     /locus_tag="PKM11_03595"
     CDS             1687..2346
                     /locus_tag="PKM11_03595"
                     /inference="COORDINATES: protein motif:HMM:TIGR00323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-6"
                     /protein_id="HNX47623.1"
                     /translation="MLRVSNYNGVEFIGVYAVANEAMALLPMDSDDRFQEDISTALDI
                     KCHKGTIASTNLIGSLVAMNSYGVAVNSFATDTEITVFSKLQVARLEDRLNACGNNIL
                     VNDNGCLVNPEMNDRTVHVLEEAFNVEVVRGTVAGQNTVGSVCKVTNKGLICHPASSA
                     ADLKMLKELFKVEPKITTLNYGSPYVGASIVANSKGGVVGMRSTPIEQGRVEEALDII
                     S"
     gene            complement(2347..2982)
                     /locus_tag="PKM11_03600"
     CDS             complement(2347..2982)
                     /locus_tag="PKM11_03600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47624.1"
                     /translation="MRIIWHMHSCFEINDRSTVVMDPHDGRSIGVKPPSLRADIVTIS
                     HDHFDHNAVRVIKGEYVLVKDIAPRTVKGVAIRGITGFHDDVNGEKRGKMNIFHLTMD
                     GVRFCHLGDLGHMLTDAHIKELGEVDVLFLPVGGVFTIDGAQAQTLVRAINPRVAIPM
                     HFRVGGLSMSIQNADGFLKGLPEEKVVRVGNEVEFEAEDLPEETEYWVFSQ"
     gene            complement(2991..4262)
                     /locus_tag="PKM11_03605"
     CDS             complement(2991..4262)
                     /locus_tag="PKM11_03605"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47625.1"
                     /translation="MDRKSSFKECPKCGLRNKPGAAQCDFCGQNLTVSDDWQQHIKDL
                     ESLNKMELRKPLDDRTSKRIESTIVRKDPPASKNGGIKEAGNIGKALKDLDEPSIREE
                     RPRPAPAQEKFTIREAGNIGKALKDLDEPSVREERPRPAPAQDHKKIKETVSAPLAND
                     EPKVEAQVSAGSTIADLLREPSKESPMATPPAEPQVDREVPSLGPSADEVIEETNKEP
                     VELPPLSEVVPEPEKADAPSSVPMTEPQTIVKPEGTRDPEPRSTVDEEAAKEVPVANV
                     QTVQKDIGPNEAHNDEKPNVPLASDDKHETIKLKLVEVERPKEKLVPITVRNRFRSSG
                     MAAIVVLGLGIAAYLVVLTMTALGILGTVEGLGGGAVSSLMIIYGASVTYPALRKEKG
                     TDVYMCPKCHEKVEKRSHGCPACGAEFENED"
     gene            4395..5552
                     /locus_tag="PKM11_03610"
     CDS             4395..5552
                     /locus_tag="PKM11_03610"
                     /inference="COORDINATES: protein motif:HMM:NF016048.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF373 family protein"
                     /protein_id="HNX47626.1"
                     /translation="MKVLILSVDRDDDFGKKAGLNSPFIGREENAMAVMALGLKDPED
                     SDVNTVMAALSMYDEMLKKGEDVEISTICGDPKVGYQSDLVLTTQLENVLELVKPDRV
                     ILVSDGAEDEFIYPMVFSRVKVDSVRRVWVKQAPTVEGTYYIITKMMSDDKMRKRIFT
                     PLGMVLSVLGLFNILPQLIKLLAQEASVETVASMGWGMIALVLGLYMISFAFRVAERV
                     DQSIKNTGTAIRNGSQMIPFVIVSILLFLAGIIFAIDSAATLSEAGYFVQSFAVLSIL
                     LWMWAFSLISYQMGKMVNHYLNFNKLYVTSLVVSISIFAIAFILQASFDLVSLVFDYP
                     HPTEQYIVFMVVVGFLLAGFSGLINMNMRNFTRMAKQSQDADPEPQNYPEA"
     gene            5626..6210
                     /locus_tag="PKM11_03615"
     CDS             5626..6210
                     /locus_tag="PKM11_03615"
                     /inference="COORDINATES: protein motif:HMM:NF014075.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF115 domain-containing protein"
                     /protein_id="HNX47627.1"
                     /translation="MRSAEKLSELVVSKKILGYRTIVDRLGQRVSIIGASASLERDIG
                     TLSEEDTVISAGSATARLMKNGIIPDILVTDLDGDVDYEVEAIDKGSLAFIHAHGDNL
                     DRINEIVPRLTMPFVPTVQCQPFGNVYNFGGFTDGDRAVLIASHFGVKNIRTLGWDLE
                     HPFIKEGSDPDMKLRKLRWAREILSRSIDYGVRL"
     gene            6642..8282
                     /locus_tag="PKM11_03620"
     CDS             6642..8282
                     /locus_tag="PKM11_03620"
                     /inference="COORDINATES: protein motif:HMM:NF012706.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HNX47628.1"
                     /translation="MVATISGNPESLDPAVDYETVGGEVIQNVYETLMFYDGDSAATL
                     VPMLCTEVPTVANGLVTDNGLTYTYHLREGVKFHDGTDMTSEDVFYSFARALRLNDPN
                     GPAWMVGELLIPDYYDYSRGKYLSDGNLNATSGVPMDVIYDHIWMKDAYTVQFNLTVA
                     FPGWNYVITFGVGSIVSKDYVEANGGMTQDGYNYMFSHMCGTGAFSLESYYPDTHFIL
                     ARHDGYWREPAKLSKVIIRQIPDANTRLLLLKSGEADVASIPRTLRSSVISDSNIEVT
                     EGKPTFNIDFIGLNQKINFNSTAAPNTNVPANFFADKNVRLAFAHAMNASKLIATQFY
                     GAGIQPNGAIPKGMFGYNASVPTYTYDLALVKSYLENASTPGNTSNYLAEGFNIDIFY
                     NTGNTVRQTACEMFRDGLQAANPDKIHVTITGVEWATYLALRKAGSMPVLFLGWAPDY
                     ADPNNYMQPFFHSAGTYASMCGFGNDTLDAMIEQAAGELNPETRTTLYYELSMYLYGE
                     CLHIWTVQATNFHCERVSLDGYTFNPMYSGLYYYPMDK"
     gene            8359..9378
                     /locus_tag="PKM11_03625"
     CDS             8359..9378
                     /locus_tag="PKM11_03625"
                     /inference="COORDINATES: protein motif:HMM:NF012738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47629.1"
                     /translation="MRLSKYIVKRILLLIPVLIGVSIIIFALSRMTGEPAAAYITDKM
                     TPAQIQQVYEKYHFDEPVVNQYWYWLTGILEGDWGFSKIAGVPVNEAILVRLPVTMEL
                     TLLSMAIGIPIGITLGTKTALRKDKTFDHVVRVISLVGVSIPVFWLALILQYVFYYKL
                     DILPAAGLYDIVRWSFTPIPDITGFLIIDSLLVGNFRLFGDHILHMVMPAVTLSFGTI
                     AVLIRIQRNSMLEVLNLDYIKTARAKGLPEKTVINKHARRNALIPTTTVVGLSFGGSL
                     GGAVLTESIFALPGLGRWSASSITHFDTTSILGFVLFIALVYSLVNLAVDIMYAYLDP
                     RVKLE"
     gene            9383..10360
                     /locus_tag="PKM11_03630"
     CDS             9383..10360
                     /locus_tag="PKM11_03630"
                     /inference="COORDINATES: protein motif:HMM:NF012738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47630.1"
                     /translation="MADMNDDKKQGRAMNTDNLGRSEHSVLDEFVAEMKPRVRGWEES
                     LKSIGHNPTVLLGLILILAIVAIALFAPYIAPPDPLVVDPYRIPKDYILPPRAPGVDG
                     YLFGSGDMGLDVFYGVVWGARTTIYTSLIVVIMATLIGLILGSIAGFYGGKTDQLIMR
                     ITDVFLSLPALILAMAVSSILSKDLNSIIFALIIVWWPSYARLIRGQVLTIKENTYVE
                     AAKAIGAKNSRILFRHVVPNSLTPMIVSVTMDIGSVALTAAALSYIGFGVDTGYAEWG
                     RMVSDGQQWFVAGYWWTVVFPGMFILLFTMGFSLVGDGLRDILDPRTKR"
     gene            10365..11774
                     /locus_tag="PKM11_03635"
     CDS             10365..11774
                     /locus_tag="PKM11_03635"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47631.1"
                     /translation="MHDKNFIKISGLFVNFYTKSGVVKAIDGVDLEINQGETLGLVGE
                     SGCGKSVTANSIMRLVPSPPGKIENGRILIDLPVDLHQRLVDIEKEEHLGADPSVVKK
                     KLDEIAPDLDKYDVLKKSKYQMRKIRGKQISMIFQEPMSALNPVFTIGFQLTEILYLH
                     EMPDLIKGALLRLEEARTKTKNSAPVESALPELEEPKCAVCSSPLTSSHRRCPYCGSD
                     LHKVNRNGFALWNMKREEKALMDMSKDPESVKLMFMNRIPFLNSYKKRLENEALGKAV
                     RMLRLVRIPDPGNIIKNYPHELSGGMQQRVMIAMALACKPRLLIADEPTTALDVTIQA
                     QILKLMRELQEEMGTTILMITHNLGVVAEVCERIGVMYAGNIVEIGATDDIFAEPLHP
                     YTQGLINSIPSVTSNVDRLEVITGSVPNLLHPPSGCRFHPRCPFAMPICSVEKPLLED
                     IQENHRVACHLYGKVNNNE"
     gene            11767..12861
                     /locus_tag="PKM11_03640"
     CDS             11767..12861
                     /locus_tag="PKM11_03640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HNX47632.1"
                     /translation="MSDDVLFEIRHMQKYFPIRGGVLGRSLGNVKAVDDINLSIRRGS
                     TLGVVGESGCGKTTAGRCTLMLTRPTAGNIYYEMPGNLRERMLELEAEEQALLEKDPL
                     AKKKKKGLLPELEQMREEYALNRRSPEDLRRLRKNMQIVFQDPYSSLNPRMLIKDIIA
                     EPMKLHGLSSGINVTNRVKELMERVGLAPEHIYRYPHEFSGGQRQRIGVAKALALNPN
                     FIVLDEPTSALDVSVQSQILNLLNDLQRELDLTYMFISHDLSTIKYMCDTVCIMYLGK
                     IAEIGDKKAIFDRPLHPYTEALLNSIPVPDPKLKRKRVPLSGDIPSPANPPKGCRFHT
                     RCKYREAICEEIEPQLEDKGNGHLVACHFR"
     gene            12870..13193
                     /locus_tag="PKM11_03645"
     CDS             12870..13193
                     /locus_tag="PKM11_03645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47633.1"
                     /translation="MASKRKLVVTRSDDDEGSKEHRSDREIMIEGTWTEWFQKVFLKY
                     CYVVGILFLACMVPLEVVRQLDGDLGLGLAFLAVLLIVPLGFFGYLKLWGDGGVWGSE
                     LTNDN"
     gene            13270..13644
                     /locus_tag="PKM11_03650"
     CDS             13270..13644
                     /locus_tag="PKM11_03650"
                     /inference="COORDINATES: protein motif:HMM:NF039321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47634.1"
                     /translation="MTLDDLVKALANTIGKKGMSHEDQEKLAEWILSFFGYTDEVIDN
                     KLTSEDRDVFYWLEEEGFLTTTQEEVHLKKGKLWRIHYWILKKDQILRIAHQCEDDVC
                     GPDDPSAVYNNMDDDMWKARER"
     gene            13679..15292
                     /locus_tag="PKM11_03655"
     CDS             13679..15292
                     /locus_tag="PKM11_03655"
                     /inference="COORDINATES: protein motif:HMM:NF014244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HNX47635.1"
                     /translation="MYEDILLVLLAIVAFVFLVRLADRKGWIKKYGMKAYGPFLMWST
                     QRGKKAIDRLATPKKFWLAYAAIAKWVCAVVMFLMMALLLWEATIVDQIPAENAPGLE
                     MMLGIPGINPIIPVWYGILGLLVAIVIHEVAHGILTRVGNMDIRSMGLLLLIVPMGAF
                     VEPDEEALGKADKRRRMNVYAVGPATNIIVGLVCALIFSSAMMGSVEPVQENPIVVSV
                     ANNGPADMAGLRFGAQIMEIEGTAIGTYDDFYAFSGPDPGQNVTVSYYYEGELRNTEV
                     VAGVVLTSISSGYPASEAGMKPGMIIYSLNDTVIRNDSDLKGVLRSTVGGQTVNATVL
                     VYDRSVGYYVPEPSVTNVTLMSRLAYYQEVSPGTVDDNFEDYGFMGINSAYMGAGVND
                     PGIILDRLATPYADANDVSSYVTSSLRYIALPFYGLAPLTSTITDLYEPQGAWSVLPD
                     SVFWVLVNSAYWIFWINLMVGMTNVLPAVPLDGGYLFRDGLDALVKKVRKNASDEDRK
                     KYVGKITYALALFVLFLIMWQLIGPRLLG"
     gene            complement(15293..15466)
                     /locus_tag="PKM11_03660"
     CDS             complement(15293..15466)
                     /locus_tag="PKM11_03660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47636.1"
                     /translation="MTECPSFKPLFSVFLKCRDCGRIYDPYSSLCSLDYELCPECNHP
                     GDILPMITFVCRE"
     gene            complement(15681..17714)
                     /gene="nrdD"
                     /locus_tag="PKM11_03665"
     CDS             complement(15681..17714)
                     /gene="nrdD"
                     /locus_tag="PKM11_03665"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HNX47637.1"
                     /translation="MFVRTSDEEIKKWDKSRIYDALMRETDISEDAAAIVSREVEKMI
                     GELQLDVITAPLIRELTNAKLVEYGLAKIRRQHTRLGVPLYDARQIIMSPNKENANVP
                     HGPEATNLTLAEQIKKEFALLEVFSQDLADAHMRGDIHLHDLGMIDRPYCSGQSIEYV
                     KKFGLNLPNAISIAKPAKHPEVLIEQVVKFSAALQGNFAGAIGWDAFNLFLAPYLTDV
                     DDARMKQLAQILIFEFAQQAVARGGQSIFSDLNLYWEVPDHFVNVPAIGPSGQLTGKV
                     YGDYAKESQRFVNALFDVYLEGDAMGRPFFFPKPNVHMTEKFFKTEGHEEFLNKICQT
                     AAEKGNTYFVFDRGGTAKISECCRLTFKLDENDLNDAKTPWKMRYSAMQNVTINLPRI
                     AYEAHQDDEKLFRLLEEKIELVAQAHLQKKEFIGKLLGMGKYGPLSLLSMNLDGEPYY
                     RFEKASFLIGMVGLNELVQYHTGQQMHESKEATKFGLKVISVMKKHAEAIGLKYGIKM
                     PLEQTPAESTAYRFAKLDMKYYPLQAPTVMRGNKSTGEIYYTNSTYLNVGAQISAIER
                     VKAEGLFHPLVEAGALSHVWLGEHKPPAENLAAFVTKTFLHTQNSQIAFSPEFTSCLS
                     CGKTARGLSDTCSYCHSPNVEGITRVTGFFSKTSGWNKGKLGELKERTKNIIS"
     gene            18105..18575
                     /locus_tag="PKM11_03670"
     CDS             18105..18575
                     /locus_tag="PKM11_03670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47638.1"
                     /translation="MHRLTLTGYLRALSDMNVLKEKDVPPAKIYTPVKGKERDIYLRV
                     AEQAKALALDKYPELTLYTLYKLFKRPIFKEELERAGVFEFSPGVQAKDEEIVDVRKF
                     MQKTGFKIPTSSKAYVPENEDLESLFQGLLAQILINDSECSYLVKETKQVKLDL"
     gene            18622..19629
                     /locus_tag="PKM11_03675"
     CDS             18622..19629
                     /locus_tag="PKM11_03675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015948 - methanogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker 2 protein"
                     /protein_id="HNX47639.1"
                     /translation="MELNDLVESLRTFPGVTRKKSISSVINFFPKQASTKILASYGED
                     AAVVEQDDKLLLLAADGIMPALMRANPFFAGYYAVLVNIHDIAAMGGVPIAMLDILSV
                     KDNRVCSQVMKGMESAVKKFGVPIVGGHTHPDCDYDAIDIAIIGTAEKGQAIYSHTAQ
                     AGDDVIVGMDLDGYYPDALPYAWDTTSRKEAPLLRRQMLIMNKIAKQGLVRSGKDISN
                     PGTLGTLGMLLETSGKGAIVDVDRIPRPQGVELVQWLKSYQGCGYVVTCDPANSQKVV
                     EMYATVGVTGAVIGKVTDEPKLIVNQGAKSAIMFDFDKDVITGCKPTSTVGWESVEMG
                     K"
     gene            complement(19632..19943)
                     /gene="ffs"
                     /locus_tag="PKM11_03680"
     ncRNA           complement(19632..19943)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PKM11_03680"
                     /product="signal recognition particle sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01857"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="archaeal-type; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01857"
     gene            20096..20992
                     /locus_tag="PKM11_03685"
     CDS             20096..20992
                     /locus_tag="PKM11_03685"
                     /inference="COORDINATES: protein motif:HMM:NF012738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HNX47640.1"
                     /translation="MGRTKSRNGQMGRKEAMDKALKDGRSHFEFRPETRKFLLSNSLN
                     IAVGIALVIAVWWILAEAMIYTRGALFPTPPETFSALWSALNGAELNGETIYYHTGSS
                     MLRWGIGYAIALIIGIAVGISFGTLSRIYDTGMVSVYVIQMIPGLAWVPIAMLIFGLG
                     ESATIFIILMTAMPPIIINTAGGIRQVPPVYTRVALMSGKDKISLFTSVLIPAASLSI
                     IDGMRIGLANGWRVLIAAEMVLGAMVGLGATIYDSRYSLDFVSAFICIIVICFIGLAI
                     EKMFFAGLENMVRNRLGLDKEV"
     gene            20994..21794
                     /locus_tag="PKM11_03690"
     CDS             20994..21794
                     /locus_tag="PKM11_03690"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47641.1"
                     /translation="MLASLKNVSKVFANPRTGKGLVALNDVSIQVEKGDFLCLIGPSG
                     CGKSTTLNLLAGFEHPSEGELMFNGKPITGPSPERGVVFQEFSLYPWMNVLQNVAFSV
                     RAGNRSEMEGIARKYLGMVGLLDFAHAMPNELSGGMKQRVAIARTLAMDPDLLLMDEP
                     FGSLDEQTRRKLDNEVLSLWEGQGKTVVFVTHCIEEALMLGTRVVLMSASPGRINKEW
                     KIEMPWPRDPLSPEMIALKKDVVKSLQVCSCANGSAQGVFITINGLEE"
     gene            21822..22787
                     /locus_tag="PKM11_03695"
     CDS             21822..22787
                     /locus_tag="PKM11_03695"
                     /inference="COORDINATES: protein motif:HMM:NF024772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HNX47642.1"
                     /translation="MNKKMLAIVLVIVVVIAAVGVAILMMSSDDGEMDLTVAYSEKMN
                     YETLMVANDKGYFDDVGLNVTPAIVTGGIQAAEAIVTGSADVAAMGDAPAVQLISKGI
                     GAKIIGRIAGAEGMHRIISDSNLTEPEDLEGKKVGMQQSSSSHGAFLQWCKANEVDTD
                     LVKFVYLNPTYLAEAMYSGQIDAMVGSEPWAINTENLCGDSVHELGSSSGLGSSFPIV
                     LVASHKALTEKGEALSRLLEALDMANDHINGDWNDSMDICAAHTGLTVGNQSKGSGLQ
                     FFELGFNATDVQSLTMTAMGLMDFGKIDTVPIIMDHVDLSYLPEE"
     gene            22792..23853
                     /locus_tag="PKM11_03700"
     CDS             22792..23853
                     /locus_tag="PKM11_03700"
                     /inference="COORDINATES: protein motif:HMM:NF013381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HNX47643.1"
                     /translation="MRRNGRQLFMGSLEGEVPEVPPVFLRDLTLGLDETGYGTPEVCA
                     GTYDADKSARSVLALHGRLGQDAVVGCIHYVGLEIEALGGRVKYPDRGIPSVVRHPFQ
                     DTNDPEFVLLDMQRDAPFPNVARSYRLVGEGLEGNAALVCNIEGPVTKASLLRGMENL
                     ALDMFFDKDLAAKYVDFATDISMEFLQAVNEQADLDCSFLASASDNPDIFGTEAFQRF
                     TVPNLRRISDASAALGLPSIFHPHGDMSSPENLPLMDDVIATGVEGFQFAERNDHLVL
                     RKAFGERITLMGGIDAFSTLLLGPVERIARETEVFLNDFRPWSHYVFMCSCSLHRGMP
                     LDHVDAMMRSVLGFAKKDI"
     gene            23880..24758
                     /gene="lipA"
                     /locus_tag="PKM11_03705"
     CDS             23880..24758
                     /gene="lipA"
                     /locus_tag="PKM11_03705"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: protein motif:HMM:TIGR00510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HNX47644.1"
                     /translation="MAPPDVSEKPPWLRTKVVMASGMGVRGALDSCGLRTVCDSSRCP
                     NLGECWGKGHATFIILGERCTRSCQFCAVPSGTPSETDPDEVGNLAEAVRRLRLRHVV
                     VTSVTRDDLPDGGASIFAEVVREVRWNNPGTTVELLIPDLQGNREALETILEVAPDVL
                     GHNIETVRSMQWIRDRRASYERSLGVLKMTKDISPGTLTKSSLMLGLGETREELVQAM
                     KDLRSVGVDLLTLGQYLPPKGSNLQVRRYVPPQEFEELHDLAMGMGFKGARAGPLVRS
                     SYDAFDLMIEAGARRC"
     gene            24752..25807
                     /gene="pdhA"
                     /locus_tag="PKM11_03710"
     CDS             24752..25807
                     /gene="pdhA"
                     /locus_tag="PKM11_03710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045250 - cytosolic pyruvate
                     dehydrogenase complex [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HNX47645.1"
                     /translation="MLTDDFDPMKGEMLQIMDEDGNVDSSLMPKLSKDLLLKAYRNML
                     LTRLADDKAVKLQRQGRLGAYPPSKGQEASQLGPAMALNDNDWLVWAFREMGALLWKG
                     VPLQTQYLYWMGNELGNVYPNGVHVTPSVVPVGSQVPHAVGIAYASKLRGEKDVTLAY
                     FGDGATSEGDFHEGLNFAGVFRTANVFVCQNNQFAISTRRNKQSASATLAQKAVAYGF
                     PGILVDGNDVLAMYAATKEAVDRARNGEGPTLIESYTYRLSDHTTSDDWRKYRSKEEV
                     AEWERKDPLKRFRSYLVAQNMIKDDEPLMKELTDIVERAAAEAEAVPAPTRSDAFVHT
                     YAEMPPYLRGQMGGGGK"
     gene            25804..26769
                     /locus_tag="PKM11_03715"
     CDS             25804..26769
                     /locus_tag="PKM11_03715"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HNX47646.1"
                     /translation="MMMNMVQAINSALSMEMERDPSVVVLGEDVGVDGGVFRLTDGLI
                     DKFGEARVIDTPLAEAGIAGVAIGMALNGLRPVAEIQFMGFSYLTLNQMINHAARMRN
                     RTRGRLTVPMVLRMPYGAGVKALEHHSESTEALYAQIPGLKVVVPSTPLEAKGLLTSS
                     IRDPDPVIFLEPTRSYRMLKEEVPDGEYLVPLGKARTVQEGDDVTVIGWGAMIPLIQR
                     AVANVQASVEIIDLRTISPMDSETIVTSVKRTGRAVVVHEAPRSFGVGAEIASRIYEG
                     AILKLEAPVERVTAPDITVPLPKGEDHYYVNEQMIRDGIERTLRF"
     gene            26779..28011
                     /locus_tag="PKM11_03720"
     CDS             26779..28011
                     /locus_tag="PKM11_03720"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012424.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="HNX47647.1"
                     /translation="MATEFRFPDLGEGIAEGEVKKWLVKVGDTVTKDQSIAEVETDKA
                     VVEIPSPVAGKVLRLDHQEGELVKVGEVLAVIGEEGDVAPTNVPPPMTEEERPASVSV
                     VGELPREEVVVTSVTQKRTSRDVSAMPAVRKAARDRGADITAVTPSGPSGQVLESDLG
                     AKRSPRTVPKFDIYGYVDRVPIRGIRRTTAKRMLESQQRTAAVTSMEQADVTRLVGMR
                     ERLKAPMKEQKGVNLTYMPFIVTAIVRALKLHPLLNSMIDDEREELIIKKYYNIGVAV
                     AIDEGLMVPVIKAADQKSLWELAEEIASLAKTAQERKIDLADLKGGTFSITNYGVFGG
                     TYGTPIINYPETAILGIGRIMDAPLVVDGTIKARKVLPLSLTFDHRAYDGAVAAKFLR
                     DLVRLLENPEELLLNMDG"
     gene            complement(28016..28765)
                     /locus_tag="PKM11_03725"
     CDS             complement(28016..28765)
                     /locus_tag="PKM11_03725"
                     /inference="COORDINATES: protein motif:HMM:NF015084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoate A/B protein ligase family
                     protein"
                     /protein_id="HNX47648.1"
                     /translation="MLRKRWRVLRYEEASAAFNMALDEAIAEAVSFRVAGPTMRFYGW
                     KPAAVSVGRFQKIEEVVDLEGCKKLGVDVVRRSTGGGAVFHDREITYSIICPEDMMPA
                     DINEAYREIGGMIVNALKFLGIEGTFEPINDVLVNGRKISGSAQSRRKGMFVQHGTLI
                     YDLDRVKMFSVLKVPKDKLDSHSLGDPAERVTSIREQKKVPWEYATAAMANAFIMNRQ
                     WYSGDITQDELARAELIAKTRYANDEWTFER"
     gene            complement(28759..29034)
                     /locus_tag="PKM11_03730"
     CDS             complement(28759..29034)
                     /locus_tag="PKM11_03730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47649.1"
                     /translation="MERRVRVAGGKTLVLDVDCQGEEVVRIRISGDFFFYPEEGLAKL
                     ESFLVEEKVWKANDPGAIIADYLSENDLRAVGFGPSDLAFLLRGSKC"
     gene            complement(29039..29323)
                     /locus_tag="PKM11_03735"
     CDS             complement(29039..29323)
                     /locus_tag="PKM11_03735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47650.1"
                     /translation="MSEKRLIWFHGRECPHCRKLAPVVEQFEAETGIKLEKLEVWHNE
                     ENAKLMRTLADIIAPACGGDLGVPAFYNEVTGKAICGRIDMAKLVAWAKG"
     gene            complement(29320..29751)
                     /locus_tag="PKM11_03740"
     CDS             complement(29320..29751)
                     /locus_tag="PKM11_03740"
                     /inference="COORDINATES: protein motif:HMM:NF014939.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016730 - oxidoreductase activity, acting
                     on iron-sulfur proteins as donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-thioredoxin reductase catalytic
                     domain-containing protein"
                     /protein_id="HNX47651.1"
                     /translation="MKKLWRCHVCNDVHLGNKPPEVCPTCGARNAFVLSDLGEALEII
                     GKDHTPLDDQSKVLAAWKQFSDQSATVKLTDKADEVELLSKGVMENLKGKGQRYCPCR
                     ITTGDRVKDLNLICPCNFIRQPTYKETGECWCGLFIKRDVQ"
     gene            complement(29798..30304)
                     /locus_tag="PKM11_03745"
     CDS             complement(29798..30304)
                     /locus_tag="PKM11_03745"
                     /inference="COORDINATES: protein motif:HMM:NF013077.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HNX47652.1"
                     /translation="MSKDPILERRSVRRYTAQDVEEKDVRKLLEAGMSAPSAGNERPW
                     HFVVIRDRRTLEGVMEFHPYAKMIKECAGAILVCGDPSLEKYPGFWVQDCSAATENIL
                     IMAVQLGLGAVWLGIYPIEERVNGLRKLVGVPDEVVPFSLIPFGHPAEVRKLIDRYDQ
                     QRVRLEKW"
     gene            30388..31005
                     /locus_tag="PKM11_03750"
     CDS             30388..31005
                     /locus_tag="PKM11_03750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
                     /protein_id="HNX47653.1"
                     /translation="MAGFEELIYCTTLLFFIFDPFATVPMFITLTRDQTPKEQMVSAN
                     KAVLVAGLLFVIFALIGAELLGLFSISVDAFRIAGGIVLLLMAMEIIFSLQLSKKEET
                     SVAWVIIATPLLSGPGVITTAILLVHLYGHFTVLIAGVISLAITWGIMRNSLLISQKV
                     GNNAIDVFSKIIGMLLAAIAVEFIMRGSVDYVLNSLSLGFSLLPL"
     gene            31047..31322
                     /locus_tag="PKM11_03755"
     CDS             31047..31322
                     /locus_tag="PKM11_03755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47654.1"
                     /translation="MASESMADCKKCDSSLEAIQLDETPKLQVRGRDVGINALDDIMK
                     DIRSRNLQEPELGTALLGEVKRLDYVPPSMEKDYRAALLQDYQRRFG"
     gene            31359..32090
                     /locus_tag="PKM11_03760"
     CDS             31359..32090
                     /locus_tag="PKM11_03760"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47655.1"
                     /translation="MNKCTICNSNEHPARTGSVKMMAVSNQVDLRLEIHEAHLRVLDI
                     SVHLLGYINAYRALSELPDYLGRRRTRYAMVLIMLDEMAPLMELMKECERGITEHSAE
                     IVINGFFSPQSRQDRMERVLDEIGKSELLFLKVKKNLGREPSAIDFSVFKDQFRRADG
                     NLFPAVERALRYDWSCGEDGMPGEEQIEMLFLAIELTVRGAAEFSHQWALANEYDIDF
                     KLETRYSKDGVDRRKEKGYWVKTPL"
     gene            32097..32483
                     /locus_tag="PKM11_03765"
     CDS             32097..32483
                     /locus_tag="PKM11_03765"
                     /inference="COORDINATES: protein motif:HMM:NF012314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HNX47656.1"
                     /translation="MAGEIKDVSDELFLDLLRKEKRFIVVEFWSPGCSVCKEVEPEVL
                     KAQAELGPDVLFMRINTDHNKQLATRYQITGTPTFVYFCKGDKIGGAIGYINATVLRN
                     TVKDLIRHSASCPSGKRVSYEMDGYG"
     gene            32517..33764
                     /gene="hisD"
                     /locus_tag="PKM11_03770"
     CDS             32517..33764
                     /gene="hisD"
                     /locus_tag="PKM11_03770"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HNX47657.1"
                     /translation="MWQVLSVESWKARGRSDLSKVIPTVSDIIEQVRKEGDAAVLRLT
                     ARFDKVDLTDLRVSRAEIDEAYSKVDQELLEALKFAKMRIEAYHQRQRPEDVTLFKDG
                     ESYLGWKYSPLGSMGMYIPGGKASYPSTALMCAVPAKVAGVRNVIACTPPPVHPLTLV
                     ALDLAGVDTIFKCGGAQAIAAMGIGTLSVPKVQKIVGPGNIYVTAAKVLLRQEVEMDF
                     PAGPSEIAVLADGTARAENVAADILAQAEHGPDSACALVTDDPALARKVGELLERQME
                     KSERQDLIRSSLKNSGYIMVKDMFEGVAVCNELAPEHLSIQTSDPLSILPSIETAGAI
                     FMGDDSPVACGDYTTGTDHVLPTAGNAAVHSGLDVLHFMKRSSVQMLDLKTLKDLAPA
                     TIRLAETEGLQAHAESVRVRLKK"
     gene            complement(33774..34184)
                     /locus_tag="PKM11_03775"
     CDS             complement(33774..34184)
                     /locus_tag="PKM11_03775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47658.1"
                     /translation="MVAIPNEVMQVINDPASVRVLATKSDKGDVHIIQAGSIKAPAPD
                     IVVIGAILMKRTGKNLEGMKAKGELVSILAGSKMQSYEIRAKVKELATSGPIFEGMNA
                     ELSKMGMKASGVWVFEVKEVWNQSANYSAGTKMV"
     assembly_gap    34348..34447
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<34448..34966)
                     /locus_tag="PKM11_03780"
     CDS             complement(<34448..34966)
                     /locus_tag="PKM11_03780"
                     /inference="COORDINATES: protein motif:HMM:NF013429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HNX47659.1"
                     /translation="MSFFGIPALIGYQELRPNLDLCKDLGLDFVELNMNLPYSFPENI
                     STRDVRAAMKDGMRFSVHLHDELDLGSLQPSVRQGHLDRCEEALRWGSRHGVFLINLH
                     LNPGVYFTLPDRKVWVYERYLEEHIESLNDSFGRLSSLAESLGIKICVENTGHFILPF
                     MRKAAESVIDLPS"
     gene            complement(35008..35604)
                     /locus_tag="PKM11_03785"
     CDS             complement(35008..35604)
                     /locus_tag="PKM11_03785"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HNX47660.1"
                     /translation="MNSRQSWDLLYQRDGRPWKGSCDEVIPMNGLVLELGIGNGKNLT
                     AFAADTSFIGLDFSRPALLACASRHEIPLLQADIAALPFPDQTFPNVAASHVLGHLDS
                     ASLKKAALEIGRVLKDGGTLYVSVFGEEDMRFGRGEEVEERTFQRGNGVMTHYFLGNE
                     IPELFPTFKMVRSWERRMEKRILGKVEIRQERRFLLLK"
     gene            complement(35601..36116)
                     /locus_tag="PKM11_03790"
     CDS             complement(35601..36116)
                     /locus_tag="PKM11_03790"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HNX47661.1"
                     /translation="MVNEERRKRQPVETILQRIGPRDGEVIADLGAGIGYLSIPLADA
                     GAKVIALDFQQEMLDGIRQRDNGQERIRLVRATLPEIPLPDASLDRVVLMNVFHEVED
                     KGRLAKEITRVLRPKGRITLVDWQARETERGPPMHERVPMGTAPSYFPGFVLERSFDD
                     PEHYHLELRRE"
     gene            complement(36187..37998)
                     /locus_tag="PKM11_03795"
     CDS             complement(36187..37998)
                     /locus_tag="PKM11_03795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HNX47662.1"
                     /translation="MLLKAEGVGKAFGPKEVLKDVDIQIELGDRIGLVGRNGAGKSTL
                     IKLLMGRLKPDVGTLNLRTSKISYLSQFVDVDHSSSVDSAMGIMSEEEAPLRRRAAEI
                     EEVMTSGGDSDTDWNALSVEYSHIQEELVRIAPQQTKDKARDILEGFGLEHKSQGSMG
                     ELSGGERTKVMLSRVLAQAQQSDLIFMDEPTSHLDIETVEWLEDQLLKLKGAVIIISH
                     DRYFLDNVATRIIELENGKLTHYSGNYSIFMEKKALDRERLWQAHDKATKEKERQEKV
                     AEELHVKYKYKSIHKTREKMAQRVEVPEPPPDEKELQVRIYSLGKSGKNVLTAKDLVV
                     ARGNRKVLDKLDLEIEKGDKLGIFGPNGSGKTTLLKTLQSKLPYLGELYVSPGVKVGY
                     YAQEHEQLDKDITAEQQMKKALGTQAVEARAILARLLLTGKDVERPISTLSGGERARL
                     ALSILLAQHKNLLILDEPSNYLDIPSKEAVEDALREYTGSLIIVTHDRYLLDAVCTKV
                     GELKDGKLSVFNGTYSEMKGRQKFAQGIEEADVYKAVGTFKDWVNKVTYKEGDKVTIA
                     KSEIENFRWALDNGKLKKVGGTELKKVRKSAPAAEDD"
     gene            complement(38035..38769)
                     /locus_tag="PKM11_03800"
     CDS             complement(38035..38769)
                     /locus_tag="PKM11_03800"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX47663.1"
                     /translation="MDVVFMGTNGWYDTDTGNTLSILVRAKDFNVVLDAGGGLHKLDR
                     YADLSKPTVIMLSHHHLDHLIGLHQLARFRFKDKVTVVGIMGTHTALHELLREPYSVP
                     LALIPYNIEVLEVKEGLHERPFNFHSRLLYHSSPCLGYRLELDGVSIAFCTDTGPCKN
                     TVELARNVDLLIAESAFRSGERSDLWPHLTPEDALDIKKQSGAKRLVLTHFDAYKYPT
                     MRDREEIEERYPGQLMVSKDDMIVKL"
     gene            38866..39027
                     /locus_tag="PKM11_03805"
     CDS             38866..39027
                     /locus_tag="PKM11_03805"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47664.1"
                     /translation="MDTRHEILLEQILEELREQTKALNELRKRVDDLERTWSSGLDDV
                     RQTVIPTDR"
     gene            39033..39842
                     /locus_tag="PKM11_03810"
     CDS             39033..39842
                     /locus_tag="PKM11_03810"
                     /inference="COORDINATES: protein motif:HMM:NF019413.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1638 domain-containing protein"
                     /protein_id="HNX47665.1"
                     /translation="MTFQRRLGIIGCPVLEDEIVYLLSGDKGLKDIFVVKDEHSEKLI
                     GKLRRKGIEIVPTSEEGLSSLPDSQGRSVVVWMKSMGLHEEPKELGKEVARSAKVMDG
                     HCATILLFYGLCGNAFKNMNLLFEDVRTPVVILTDQQGQIVDDCIAVPLGGTDGYLRL
                     LKRYAGVFYMTPAWADNWELLINKMEIARGTEMGNLDMLKMLFEMAGYNRVLLIDTGL
                     GDREVLYSKTREFSTEFNFKEVVLEPDFVSTRVSDDAYQKCLEMLENGKKE"
BASE COUNT         8742 a        10959 c        11422 g         8630 t
ORIGIN      
        1 atcatggcat cgaagcggtg actgccagag gcgaccgggg cgaacagctc gtcctcgtga
       61 tacacctcgt cggcgagctg cagtacctgc tcaacggtat aggcggtctc cgcttccaat
      121 atgcgcttcg ccgtctcggt gatgatgagc gccttctctc cctctaactc ctcaagcagt
      181 cttattccgt agacgatgcc cgatgccccg gtgatagcca cgacggtctt cacgttccca
      241 attaagcact gacgcgtata tcaaatctta ccgcttggtg ccccgaaacg ttctatatga
      301 gcggacctta tagttcgtat agatgaaaaa aatcaggccc ggtaccgcct gcaaggtccc
      361 gctggggaag gcaccagaag ggatttggag aacgagaatc cttatataga ggtaccatat
      421 tagtggccga acataccatt cggtctagtc tatatctgaa gttcattgag gttggttaag
      481 atggttacgg tctatgatgc gccctccgat aagctgatcg cgaacgttgc tcagaagttg
      541 aaagactctg ggtcagttag tcctcccgag tgggcggagt tcgccaagac tggcgttcac
      601 acggagaagg ctcctatcca ggtcgactgg tggtacacca gggcggcctc ggtgctgaga
      661 aaggtctaca ttaagggtcc aattggtacc tccaagctcg ccgcggagta cggcgggttc
      721 aacgaccgcg ggtcccggcc taaccgggcc gtcaagggaa gccgctccat aatcaggaag
      781 tccctgatgc aactggagtc cgctggcctg gtggtcagga acaagaacaa cggccgcgtg
      841 gtcaccccca agggccaggc ccttctggat aacgcagcca aggaagtcgt cgactccaac
      901 tgaacgaggt gatgttcgtg gacgatgctg atctgatgga actgcgccgg cggaagatgg
      961 ccgacatgca gcgccaggga gagcagcagg cggccatgga gcagcaggcc caggcaatgg
     1021 aggtccagag gcaggcgatc cttcgccaga tactgaccac cgaggcccgg gaccggctgg
     1081 ccaatgttcg catggcatac ccggacgtgg cccgttccgt cgaggaccag ctcataaggc
     1141 tggcccagaa cgggcagata aattcgcaga tagatgagcc gaccctgaag cagatactca
     1201 ggaaggtctc ccctcagaag agggaaatta acattgagag gaagtaatat ggcacgcaac
     1261 aagcactccg ccatgaaggc gcgattgatg aagaaggtga agcagaaccg ccgggtgccg
     1321 gcatgggtca tgatgaggac cgaccgcgct ttcctgcgcc accctatgag aaggaactgg
     1381 cgccacagca agttgaagga gtgagctaaa tggcagaaga gaacgagaaa gtatacatca
     1441 tcccgcttat caagaccaag atggtcccta cccctggccg gtccgaccgg gcaataaagg
     1501 agatccgcgc ctacatcgct cgtcacatga agaccgatga gaaacaggtc tggatcgacc
     1561 ccaaggtcaa cgagtccatc tgggctcacg gtaagaccgc ccctccgagc aaggtgcggg
     1621 tcaaggccgt ccgtttcgaa gacggactgg tcgaagtatc cattccgacc gagtgagcgc
     1681 taggacatgt tgcgggtctc taactacaac ggcgtggagt tcattggcgt gtacgctgtg
     1741 gccaacgagg ccatggccct actgcctatg gattccgatg accgtttcca ggaggacatc
     1801 tctaccgccc tggacatcaa atgccacaaa ggaaccatcg ccagcactaa cctgatcggt
     1861 tccctggtgg ccatgaactc ttacggtgtg gcggtgaaca gcttcgccac cgacaccgag
     1921 ataaccgtct tttccaaact gcaggtcgcc aggctggagg accgcttgaa cgcctgcggg
     1981 aacaatatcc tggtcaacga caacggatgt ctggtgaacc cggaaatgaa cgatcgcacc
     2041 gtgcacgttc tcgaggaggc gttcaatgtc gaggtggtgc gcggaaccgt ggccgggcag
     2101 aacaccgttg gttcggtgtg caaggtcacc aacaaagggc ttatttgcca tcccgcgtcg
     2161 tccgccgcgg acctgaagat gctcaaggag ctcttcaagg tcgaaccgaa gataaccacc
     2221 ttgaactatg gctcgccgta cgtgggagcg agcatcgtgg ccaacagcaa aggcggggtc
     2281 gtcgggatga gaagcacccc catcgaacaa gggcgcgtgg aagaggccct ggacataatc
     2341 agctgatcac tgcgagaata cccagtattc ggtctcttcc gggagatctt cggcctcgaa
     2401 ctccacttcg ttgccgaccc ggaccacctt ttcttcggga agtcccttca agaacccgtc
     2461 agcgttctgg atggacatcg atagcccgcc aacccggaaa tgcatcggta tggccactct
     2521 gggatttatg gccctgacca gagtctgcgc ctgggccccg tcgatggtga agacacctcc
     2581 aaccggtaga aagagcacgt ccacctctcc cagttctttg atatgcgcat ccgtcagcat
     2641 atgtccgagg tctcccaggt gacagaagcg aacaccgtcc atggtgaggt ggaagatgtt
     2701 catcttgcct ctcttctccc cgttgacgtc gtcgtggaag ccggttatgc ctcggatcgc
     2761 cacccccttc acggtgcgag gagcgatgtc cttgaccagc acgtactcgc ccttgatgac
     2821 ccgtacggcg ttgtgatcga aatgatcgtg gctgatggta acgatgtcgg cccggagcga
     2881 gggtggctta acgcctatcg agcggccgtc gtgggggtcc atgaccacgg tcgatcggtc
     2941 attgatctcg aaacaggaat gcatgtgcca gatgatccgc atgccctcac ctagtcctcg
     3001 ttttcgaact cggcaccgca tgcaggacaa ccgtgcgaac gcttttccac cttttcatgg
     3061 catttcgggc acatgtagac gtccgttcct ttctcctttc gaagcgctgg ataggtcacg
     3121 gacgccccgt agatgatcat caaagagctc acggcaccgc cgcccaggcc ttctacagta
     3181 cccaggatcc cgagtgccgt cattgtcaat actaccagat aagcggcgat ccctagaccg
     3241 aggaccacta tggcagccat tcctgaagat cggaaacgat tgcgaacggt tatcggaacc
     3301 agcttttcct tcggtctttc gacctccacc agttttaatt tgatggtctc atgcttatcg
     3361 tccgaagcga gtgggacgtt cggtttttca tcgttatgcg cttcgttagg gccgatatct
     3421 ttctggacgg tctgaacgtt cgctactgga acttccttcg ctgcctcttc atcgaccgtt
     3481 gatctcggtt cgggatccct tgtcccttcc ggtttcacta tggtctgagg ttccgtcatt
     3541 ggaactgaag atggggcatc ggccttttcc ggttcgggaa cgacctccga tagcggcgga
     3601 agctcaactg gctccttatt cgtctcttcg atcacctcat cggcagatgg tccaagcgat
     3661 ggtacttctc gatcgacctg cggttcggcc ggaggtgtgg ccatcgggga ttccttggac
     3721 ggttctctca agaggtccgc aatggtgctc cctgcgctca cctgtgcttc caccttcggt
     3781 tcgtcattcg ccaatggagc tgagacggtc tcttttattt tcttatggtc ctgagctggt
     3841 gccgggcggg gcctttcctc tctgaccgat ggctcgtcca ggtccttgag ggcctttccg
     3901 atgttcccag cctctctgat cgtaaacttt tcctgagctg gtgctgggcg tggcctttcc
     3961 tctctgatcg aaggctcgtc caggtccttg agggcctttc cgatgttccc agcctctttt
     4021 atccctccgt tctttgaggc cggagggtcc ttacggacga tggtcgattc gatacgcttg
     4081 gaggtgcggt cgtccagagg cttgcgcagc tccatcttgt taagcgattc aaggtccttt
     4141 atgtgctgct gccagtcgtc ggaaacggtg aggttctgcc cgcaaaagtc gcactgagcg
     4201 gcgccgggct tgttgcgaag gccgcacttc gggcattcct tgaaactgga cttcctatcc
     4261 atcgcaataa cctataccag gtttccacat tatacctttt ttccccgtag tgcataaaaa
     4321 aacttactct gaggcattcg attcaatagt cattgcatta tttttatata gatggatgct
     4381 ggattgataa ccagatgaag gtcctcatcc tgagcgtcga tcgcgacgac gattttggca
     4441 agaaggccgg gttgaacagt ccattcattg gtcgcgagga gaacgccatg gcggtgatgg
     4501 ccctgggtct gaaggacccg gaggacagcg acgtgaacac cgtcatggcc gccctgagca
     4561 tgtacgacga gatgctcaag aaaggtgagg atgtggagat atccaccatc tgtggcgatc
     4621 ccaaggtcgg ctaccagtcc gatctggtcc tgaccaccca attggagaac gtcctggagc
     4681 tggtgaaacc ggaccgagtg atcctggtca gcgatggggc ggaggacgag ttcatctatc
     4741 ccatggtctt ctcccgggtc aaggtcgatt ccgtacgccg ggtatgggta aagcaggccc
     4801 ccactgtgga gggaacgtac tacatcatca ccaagatgat gtccgatgac aagatgagaa
     4861 agcggatatt caccccgctg ggcatggtat tgtccgttct cggtctcttc aatatcctgc
     4921 cgcagctgat caagttgctg gctcaggaag cgagcgtgga aacggtcgcc agcatgggct
     4981 ggggaatgat cgccttggtc ctcggacttt acatgatatc cttcgcgttc cgagtcgcgg
     5041 aacgggtgga ccaatccata aagaacaccg gaacggcgat ccgaaacggg agccagatga
     5101 tccctttcgt cattgtttct attcttttgt tcctggccgg gatcatcttt gccatagatt
     5161 cggccgctac cttgagcgaa gccggttatt tcgttcaatc gttcgctgtc ctgagcatac
     5221 tgctttggat gtgggctttc tccctcatct cctaccagat gggaaagatg gtgaatcact
     5281 acctgaattt caacaagtta tacgtgacca gcctggtggt gagcatcagt atattcgcca
     5341 tcgcgttcat actgcaggcg tcgttcgacc tggtgtcgct ggtattcgat tacccacatc
     5401 ccacggagca gtacatagtg ttcatggtgg tggtcggctt ccttctggca gggttcagcg
     5461 gccttatcaa catgaacatg agaaatttta cgcgtatggc gaagcagtct caggatgccg
     5521 accccgaacc gcagaactat cctgaggcct aagatggaat gggccgaatg gagacccttg
     5581 tatctgcgga tcatggatga tcttgatttt gatatccttg cggatatgag atctgcagaa
     5641 aagctttcag aattggtggt atcaaaaaaa attttaggat atcgtactat cgtcgatagg
     5701 ctaggtcagc gagtgtcgat tatcggggcc tctgcatcgt tggagaggga tattggcaca
     5761 ttgtcggaag aagatactgt aatctcggcc ggctcagcga cggctagatt gatgaaaaac
     5821 ggcataatcc ccgacatatt ggtcaccgac ctcgatggcg atgtggatta cgaggtagag
     5881 gccatcgata aaggttcgtt ggcgttcata cacgcgcacg gcgataactt ggacagaata
     5941 aatgagatcg tgccgcgatt gacgatgcct ttcgtaccga cggtgcaatg tcaacctttc
     6001 ggcaacgtct acaacttcgg aggctttaca gacggagatc gggcggtcct gatcgcgtca
     6061 catttcggtg tcaagaacat caggaccctc ggttgggacc tggaacaccc tttcatcaaa
     6121 gaaggtagtg acccggacat gaaattgaga aagttgcgtt gggctcgcga gatattgtcg
     6181 cgcagcatcg actatggcgt gaggctctaa ttttttatgg tcgatcattt agcaattttt
     6241 ttttaaaacc cattttgaaa catttgtacg tataattgta gaatatcttg acattatgac
     6301 aataatgttg gattattgtt ggacgattaa agggcatttt gaagtgataa ttgggcctat
     6361 tttttatact gctggatagc tatttcgaaa gaggataatc gacaaaggta tatatagcaa
     6421 caaaatgttt aaagaagtca atctcccaac catttatggg atgggaggaa ggaggattga
     6481 gaatggaagg aaatactgat gccgaaccta gaaaggccgg tggttccaag attatagtgt
     6541 ttttcatagt cgggctcctt ttaggtgccg ggctaggcgc tggaatcatg atggccctag
     6601 gggatgacga taatggtggt caagcgacgg agaaaatcgt cgtggtagct accataagcg
     6661 gaaatcctga gagcttggat cccgccgtcg attatgagac ggtgggagga gaggtaattc
     6721 agaacgtgta tgagacgctg atgttctatg acggtgatag tgccgcaaca ttggttccga
     6781 tgctatgcac cgaagttcca accgttgcta acggcttggt caccgacaat ggtctaacat
     6841 acacctacca cctgcgcgaa ggtgtgaagt tccacgacgg aactgacatg acctccgagg
     6901 atgtgttcta cagcttcgcc cgggctctaa gattgaacga cccgaacgga ccggcttgga
     6961 tggttggcga gcttctgatc cccgactatt acgattatag ccgtggaaag tacctctccg
     7021 acgggaacct taacgcaacc agcggtgtcc ctatggacgt catctatgat cacatctgga
     7081 tgaaggatgc ttacaccgtt cagttcaacc tgaccgtggc cttccccggc tggaactatg
     7141 ttatcacctt tggtgtcggt tccatagtct ctaaggacta cgtcgaggct aacggaggaa
     7201 tgacccagga tggttacaac tacatgttca gccacatgtg cggaactggt gcgttctcct
     7261 tggaatcgta ctacccggat acccacttca tactagcccg gcacgatggc tactggaggg
     7321 aaccggccaa gttatccaag gtcatcatca ggcagatacc agacgccaac accaggctgc
     7381 tcttgttaaa gagcggtgaa gctgatgtcg cctccatccc ccgtaccctt aggagttcgg
     7441 tcatctccga ttccaatatc gaggtaacgg aagggaagcc gacgttcaac atcgacttca
     7501 tcggtctgaa ccagaagatt aacttcaact cgaccgcagc tccgaacact aatgttccgg
     7561 ccaatttctt cgccgacaag aacgtccgcc tggccttcgc tcacgcgatg aacgcgagca
     7621 agctgatcgc gacccagttc tacggtgctg gaattcagcc caacggagcg atacccaagg
     7681 gcatgttcgg ctacaatgca tctgtgccga cctacaccta cgacctcgct ctggtgaagt
     7741 cctatctgga gaacgcctct acccccggaa acacgtccaa ctacttggct gagggtttca
     7801 acatagacat cttctacaac actggcaaca ccgtaaggca aactgcctgt gagatgttca
     7861 gggacggtct tcaggctgcg aaccccgata agatccatgt gacgatcacg ggggtcgaat
     7921 gggcgacata tctcgctctg aggaaggctg gctcaatgcc agtactgttc ctgggatggg
     7981 ccccggacta cgctgacccg aacaactaca tgcaaccgtt cttccactcg gcaggtacct
     8041 atgcctcgat gtgcggcttc ggtaacgata cccttgacgc aatgatcgag caggccgctg
     8101 gagaactgaa ccctgagacc aggactacgc tctactacga gctgagcatg tacctgtacg
     8161 gagaatgcct acacatatgg accgttcagg ccaccaactt ccactgcgag cgcgtgtctc
     8221 tggatgggta tacgttcaac cccatgtact cgggattgta ctactacccc atggacaagt
     8281 gagcagttga atatcttccc aaaccttttc ccttaaattt ttttaaagat cagaatcaat
     8341 aaatggagaa gatgtaagat gcgtttatcc aagtacatag tcaagagaat actacttctt
     8401 attccggttc tgatcggtgt ttcaatcatc atattcgcct tatcaagaat gaccggcgaa
     8461 cctgcggcag cttatatcac cgacaagatg acccctgcgc agatccagca agtctacgaa
     8521 aaatatcatt tcgatgagcc agtcgtcaac cagtattggt actggctaac tggtatcctt
     8581 gagggggact gggggttctc caaaattgct ggtgttccgg tcaatgaagc catcttggta
     8641 cgacttcctg taaccatgga attaacctta ctgagcatgg ccataggcat tcctataggg
     8701 atcactttgg gcactaaaac cgcccttcgc aaggataaga cgttcgatca cgtggtccga
     8761 gttatatccc tagtaggggt gtccattcca gtgttctggc tagcgctcat acttcagtat
     8821 gtattctact acaagctgga tatattaccg gccgctggac tttacgatat agtcaggtgg
     8881 tccttcacac caatacctga cataacaggt tttctgataa ttgattcctt actggtagga
     8941 aacttccgac tgttcgggga tcatattttg catatggtca tgcccgcggt aacgctttca
     9001 ttcggtacta ttgcggtatt gatcaggatt caaaggaata gtatgctgga ggttttgaac
     9061 ctcgattata taaaaacagc aagggccaag ggacttccag agaagacggt cataaataag
     9121 catgcccgta ggaatgcctt gataccgacc accaccgtag taggtttgtc attcggcggt
     9181 tccctcggcg gtgctgtttt gacagaatcg atattcgccc tacccggttt gggtagatgg
     9241 tcagcgagtt cgattaccca ttttgacacc acctcaattc tgggttttgt gctcttcata
     9301 gccttggtgt attcattggt caatttagca gtagatataa tgtacgcata cctcgacccg
     9361 cgggtaaaac tggagtgata tcatggctga tatgaacgat gataaaaaac aagggcgagc
     9421 catgaacaca gataatcttg gtagaagcga acactctgtc cttgacgagt ttgttgccga
     9481 gatgaaaccc cgcgtcagag ggtgggaaga atctttgaaa tccatcggtc ataatccgac
     9541 ggttttactc ggattgatcc tgatactggc gatcgtcgca atagctctgt tcgctcccta
     9601 tattgcacca cccgaccctc tggtcgtaga cccttacaga atacccaagg attacatact
     9661 gccacccagg gcccccggtg tggatggcta tttatttggt tcgggtgaca tgggattgga
     9721 tgtgttctat ggagttgtct ggggggccag gaccaccatt tacacgtctc tgatcgtcgt
     9781 aataatggct actttaatag ggctcatact gggttctatt gccggcttct atggcggtaa
     9841 aacagaccag ctcatcatgc gaataactga tgtcttccta tcgcttcccg ccctaatatt
     9901 agccatggca gtgtccagta ttcttagtaa ggacctcaat agcataatat tcgctttgat
     9961 aatagtgtgg tggccatcat atgccagatt gatcagaggc caggttttga ccatcaagga
    10021 gaacacctat gtcgaggcag ccaaggccat aggggcgaag aacagtcgga tactgttccg
    10081 tcatgtggtt cccaattcgc tcacgcccat gatagtgtcg gtcaccatgg acatcggatc
    10141 ggtcgccctg accgcggccg ctctaagcta tattggtttc ggagttgaca ccggatatgc
    10201 tgaatgggga agaatggtct ccgatgggca gcaatggttc gttgcaggat attggtggac
    10261 cgtagtattc ccaggtatgt tcatattatt gttcacgatg gggttcagcc tggtaggtga
    10321 cggtctacgg gacatactcg atcccaggac gaagaggtga taaaatgcat gataagaact
    10381 tcattaagat cagtggcctc ttcgtaaatt tctataccaa atcgggcgtc gtgaaagcga
    10441 tagacggggt ggacctggag ataaaccagg gcgagactct cggattggtt ggagaaagtg
    10501 gttgtggcaa gtcagttacg gccaacagca tcatgagact cgtgccttca ccacctggaa
    10561 agattgaaaa tggaaggatc ttgatagacc ttcccgttga tcttcaccaa aggctcgttg
    10621 atatagagaa agaagagcac ctcggggcgg atccgtcagt agtaaaaaag aaacttgatg
    10681 agatcgcccc cgatctggac aaatacgatg ttcttaaaaa gtccaagtac cagatgagaa
    10741 aaatccgggg taagcagata tcgatgatct ttcaggagcc catgtcggcc ttgaaccccg
    10801 tgttcaccat cggattccag ctcactgaga tattgtatct gcacgaaatg ccagatctga
    10861 tcaagggtgc gttactgcgt ctcgaggaag cgcgaacaaa aacaaaaaac agcgcaccag
    10921 tagagtccgc attgccggaa ctggaagaac ccaaatgtgc ggtctgtagt tcacccctca
    10981 cctccagtca tcgtcgctgc ccttactgcg gcagcgatct gcacaaggtg aatagaaacg
    11041 gtttcgccct gtggaacatg aagcgtgaag aaaaagcgct gatggacatg agcaaggacc
    11101 cggaaagcgt caaactgatg ttcatgaacc ggatcccttt cttaaattcc tataaaaaga
    11161 gattagaaaa cgaagcgctg gggaaggcgg taaggatgct gcggctcgtc cgcatcccag
    11221 accctggcaa catcattaaa aattatcctc atgaactttc gggagggatg cagcaaagag
    11281 tcatgatagc catggccttg gcctgtaagc cccgactatt gatagctgat gaaccgacca
    11341 ccgcattgga tgttacgata caagcccaga tattgaaact gatgagggag cttcaggaag
    11401 agatggggac cacgattttg atgatcaccc ataatcttgg tgtggtggcc gaggtctgtg
    11461 aaaggatcgg ggtcatgtac gctgggaata tcgtggagat aggggctacc gacgatatct
    11521 tcgccgaacc actgcaccca tacacccaag gtctgatcaa ctccatcccc agcgttacca
    11581 gcaacgttga tcgtcttgag gtcattaccg ggagcgtccc taacctattg catccgcctt
    11641 cgggatgccg cttccatcct cgctgcccat tcgccatgcc tatttgcagt gtggagaagc
    11701 ccctgttgga ggacattcag gagaatcacc gtgtggcctg ccatctttac gggaaggtga
    11761 acaacaatga gtgacgacgt cctttttgag atccgtcata tgcaaaaata cttccctata
    11821 aggggagggg tcttagggag gagcctgggc aacgtaaaag cagtggatga catcaacctc
    11881 agtattcgca ggggatcgac cctaggtgtg gtaggggaaa gcggttgtgg caagaccacc
    11941 gcgggtcgat gcacgctgat gctaacgcgc cctacggccg gcaacatcta ctatgaaatg
    12001 cctggtaacc tccgcgaaag gatgctggag cttgaggccg aagaacaggc tttgctcgaa
    12061 aaagaccctt tggccaagaa aaagaagaaa ggcctcctac ctgagctaga gcagatgcgg
    12121 gaagaatacg ccctaaacag gcgcagcccg gaggatctgc ggcgactcag aaagaatatg
    12181 cagatagtgt tccaagaccc atattcctcg ctcaacccgc gcatgctcat caaggacata
    12241 atcgccgagc ccatgaaatt acatgggctg tcgagtggta taaacgtcac caatcgggtg
    12301 aaggaattga tggagagggt ggggctagct cctgagcaca tatatcgata ccctcacgag
    12361 ttcagcggag ggcagaggca aagaattggt gtggccaagg ccttggcact taaccccaac
    12421 ttcatagtgc tcgatgaacc tacatctgcc cttgacgtct cagttcaatc ccagatactc
    12481 aacttactga acgaccttca gagagagctg gacctaacat acatgttcat ctctcacgat
    12541 ctctcgacca tcaaatatat gtgcgacacc gtctgcatca tgtatctggg caagatcgcg
    12601 gaaatagggg acaagaaggc aatatttgac aggccattgc acccatatac cgaggccttg
    12661 ctcaattcca tacctgttcc cgaccctaag ctgaagcgta agagggtgcc ccttagcggt
    12721 gatataccat ctccagctaa cccaccaaaa ggttgccgtt tccatactcg atgtaagtat
    12781 cgcgaggcca tctgcgagga gatcgagccc cagctggaag acaagggcaa tggccatctg
    12841 gtggcctgtc atttccgttg agcgagagca tggcgagtaa aaggaaattg gtcgttacgc
    12901 gctcagatga cgatgaggga tcaaaggagc accgcagcga tcgagagata atgatcgaag
    12961 gtacctggac ggagtggttc cagaaggtgt tcctgaagta ttgctatgtc gttgggatat
    13021 tgttcctggc ttgcatggtc cccttggagg tcgtgcgcca gctggacggc gatctgggat
    13081 tgggcctggc gttcctggcg gtgctgctta tcgtgccctt gggtttcttc ggctacctca
    13141 agctatgggg cgacggcggc gtctggggct cggaactgac caatgacaat tgattttcaa
    13201 taaaattaac tgagttaatt tatacctcga atcttatacc tcccggggga gaacggaaac
    13261 ttgacggtgg tgaccttaga tgacctggtg aaggccctgg ccaacaccat tggcaagaaa
    13321 ggaatgtctc acgaggacca ggaaaagctg gccgagtgga tcctctcctt tttcggttac
    13381 accgacgagg tcatcgacaa caagctgacc tcggaggacc gcgacgtgtt ctactggctg
    13441 gaggaagagg gcttcctgac caccacccag gaagaggtgc acctcaagaa gggcaagctg
    13501 tggcgcatcc attattggat cctgaagaag gaccaaatat tgcgaatagc gcaccagtgc
    13561 gaggacgatg tctgcgggcc ggacgacccg tccgccgtct acaacaacat ggacgacgac
    13621 atgtggaagg cgcgagaacg ctaggtattt tatataccgc tccctttcct gaattctgat
    13681 gtacgaagac atacttctgg tcctcctggc catagtcgcg ttcgtcttcc ttgtgcgatt
    13741 ggccgaccgc aaagggtgga tcaagaagta tggcatgaag gcctacgggc cattcctgat
    13801 gtggagcacc cagcggggaa agaaggccat cgaccgcctg gccactccga agaagttctg
    13861 gttggcctac gccgccatag ccaaatgggt atgcgccgtg gtcatgttcc tgatgatggc
    13921 cttgctcctc tgggaagcca ccatcgtcga ccagataccg gcggagaacg cccccggact
    13981 ggaaatgatg ctcgggatac ccgggataaa cccaataatc ccggtctggt atggcatatt
    14041 gggactactg gtggcaatag tcatccacga ggtcgcccac ggcattctaa ccagggtagg
    14101 caacatggac atccgctcca tgggcctgct gcttctcatc gtccctatgg gcgccttcgt
    14161 ggagccggac gaggaggcac ttggcaaagc ggacaagcgg cgccgcatga acgtttacgc
    14221 cgtcggaccg gccaccaaca ttatcgtggg actggtctgc gccctcatct tctcctcggc
    14281 tatgatgggc tcggtggaac cggtccagga gaacccgatc gtcgtcagcg tggccaataa
    14341 cggaccggca gatatggccg gactgcgatt tggggcccag ataatggaga ttgaaggaac
    14401 ggcaatcggc acatatgacg acttctacgc tttctcggga cctgatccag ggcagaacgt
    14461 aacggtctcc tattattacg aaggggagct gcggaacacc gaggtagtcg cgggcgttgt
    14521 actgacctcc atctcatcgg gttacccggc cagtgaggcc ggtatgaaac caggcatgat
    14581 catctactcg ttgaacgata cggtgatcag gaacgacagc gatctgaagg gcgttcttcg
    14641 ctccacggtc ggtggacaga cggtgaacgc cacggtgctc gtttacgatc gcagcgtggg
    14701 atattacgtt ccggagccgt cggtgacgaa cgtcaccttg atgagcaggc tggcgtacta
    14761 tcaggaggta agccctggta ccgtggacga taatttcgag gattacgggt tcatgggcat
    14821 caactccgcc tacatgggag cgggagtgaa cgaccccggg atcatcttgg accggttggc
    14881 aactccttac gccgacgcca acgacgttag ctcttacgtg acctcttcct tgaggtacat
    14941 cgcccttccg ttctacggcc tggcgcctct gaccagcacg ataaccgacc tttacgaacc
    15001 gcaaggcgcc tggtcggtgc ttccggacag tgtgttctgg gtactggtca acagcgctta
    15061 ctggatattc tggataaatc tcatggtcgg tatgaccaac gtactcccgg cggtgccttt
    15121 ggatggtgga tacctcttcc gtgatggact ggacgccctg gtcaagaagg tccgaaagaa
    15181 cgccagcgac gaggatcgaa aaaagtacgt gggcaagatc acctacgccc tggcgttgtt
    15241 cgtgctgttc ctgataatgt ggcagctcat cgggccccgt ctgctgggat gatcattccc
    15301 ggcagacgaa ggtgatcatg ggaaggatat cgccgggatg attgcactcc gggcacagtt
    15361 catagtccag tgagcacagg ctgctatagg gatcgtatat cctaccgcaa tcacggcatt
    15421 tcaagaacac tgagaacagc ggtttgaacg aagggcattc ggtcacccga ttatcagaaa
    15481 aggaggtgca gttgttcctc gtacagttat cacacagact gctccgatgg atgttgatca
    15541 gtctgtgctc ggttacctgt acgtgcacca tcaaaggcac cgtcaatgtt aatccgctct
    15601 atagcataca tatacgtttg taaatcagga gcaaaaaagg aaaagggatg taaaggtgag
    15661 ggcaaagccc tctttttcgc tcaggagatg atgttcttgg tcctctcctt cagctcaccc
    15721 agcttgccct tgttccaccc ggaggtcttg gagaagaacc cggtcacgcg ggttattccc
    15781 tctacgttcg gggagtggca gtaggagcag gtgtcgctca ggccacgggc ggtcttcccg
    15841 cagctcagac aggaggtgaa ctccgggctg aaggcgatct gcgagttctg ggtgtgcagg
    15901 aaggtcttgg tcacgaacgc cgccaggttc tctgccgggg gtttgtgctc tccgagccat
    15961 acgtgcgaca gcgctccggc ctccaccagg gggtggaaca gcccttcagc cttgaccctc
    16021 tcgatggcgc tgatctgggc gcctacgttc aggtaggtgg agttggtgta gtatatctca
    16081 ccggtgctct tgttgccgcg catgaccgtg ggggcctgca gcggatagta cttcatgtcc
    16141 agcttggcga agcggtaggc ggtgctctcg gccggggtct gttccagggg catcttgatg
    16201 ccgtacttca gtccgatggc ctcggcgtgc ttcttcatta ccgagatgac cttgaggccg
    16261 aacttggtgg cctccttgct ctcgtgcatc tgctggccgg tgtggtactg taccagctcg
    16321 ttcaggccga ccattccgat caggaacgac gccttctcga agcggtagta cggttctccg
    16381 tccaggttca tggaaagcag agagagggga ccgtacttgc ccatgcccag cagcttgccg
    16441 atgaactcct ttttctgcag gtgcgcctga gccactagtt cgatcttctc ttccagcagg
    16501 cggaacagct tctcatcgtc ctggtgcgcc tcgtaagcta tgcgtggcag gttgatggtg
    16561 acgttctgca ttgccgagta cctcatcttc cacggcgtct tggcgtcgtt gaggtcgttc
    16621 tcgtccagct tgaaggtcag gcggcagcac tcggatatct tggcggttcc gccgcggtcg
    16681 aacacgaaat aggtgttacc cttttcagcg gcggtctggc agatcttgtt caggaactcc
    16741 tcgtgacctt ctgtcttgaa gaacttctcg gtcatgtgca cgttcggctt ggggaagaag
    16801 aacgggcgac ccatggcgtc tccctcgagg tagacgtcga acagggcgtt aacgaacctt
    16861 tggctctcct tggcgtaatc cccgtagacc tttccggtca actgtccgct gggaccgatg
    16921 gcaggcacgt tcacgaagtg atcgggcacc tcccagtaga ggttcaggtc actgaatatg
    16981 gactggccgc cgcgagcgac cgcctgctga gcgaactcga agatcaatat ctgggccagc
    17041 tgcttcatgc gggcatcgtc cacatcggtc aggtatggcg caaggaagag gttgaaggcg
    17101 tcccagccga tagcgccggc gaagttcccc tgaagcgcgg cggagaactt tacgacctgc
    17161 tctatgagca cctcagggtg cttggcgggc ttggcgatgg agatggcgtt ggggaggttc
    17221 agaccgaact tcttcacgta ttctatggac tgaccactgc aatagggccg gtcgatcatt
    17281 cccaggtcgt gaaggtgtat atcaccgcgc atgtgagcgt cggcaaggtc ttgactgaac
    17341 acctcgagca gggcgaactc cttcttgatc tgctcggcca gagtaaggtt ggtggcctcg
    17401 ggcccgtggg gaacgttggc gttctccttg ttcgggctca tgattatctg gcgggcgtcg
    17461 tagagcggaa cacccaggcg ggtgtgctgg cgacggatct tggctagacc atactcgacc
    17521 agcttggcgt tggtgagctc gcgtattaac ggagcggtaa taacgtcgag ctgcagctcc
    17581 ccgatcatct tctctacctc acgggatacg atggccgcgg cgtcctcgct gatgtcggtc
    17641 tccctcatca gggcgtcgta tatcctgctc ttgtcccact tcttgatctc ttcatccgaa
    17701 gtgcggacga acaaagatat ctcggtcgat tctcgttcgc tattggggct tgtattacgg
    17761 ggggattctg cgcttttcat tttactcacg ttctcaatga tctcttgttc gccaatgaat
    17821 tagtaagggg gacctctaat taaaaggtcc cattgcaccc atccaactca gggaatatgt
    17881 gattcggtac actggtttaa atgaatttct gaactgaatc tgttaacaat taacggcaat
    17941 taaccagccg tgcaaagcta tattattacc atatttgtta ccatatctgt taacatatgt
    18001 tccacccaga tagggacctc aagcagataa ttatctcgat gatctccgaa gacggcagat
    18061 ccataagtta tctatcacga gaattgaaga agcagggctt cgacatgcac cgtttaaccc
    18121 tcaccggata tctgcgggcc ctgagcgata tgaacgttct caaggagaag gacgttccac
    18181 cggccaagat atacaccccg gtcaaaggaa aggaaaggga catttacctc cgggtcgccg
    18241 agcaggcaaa ggcactggcc ctcgataaat atcccgagct gaccttatac accctttaca
    18301 aattgttcaa acgccccatc ttcaaggagg agctggagag ggcaggcgtg ttcgagttct
    18361 cacccggagt tcaagccaag gacgaagaga tcgtggacgt tcgcaagttc atgcagaaga
    18421 cgggcttcaa gataccgacc agcagtaaag cgtacgtccc cgagaacgag gacctggaaa
    18481 gccttttcca aggtttgctg gcgcagatac tcatcaacga ctcggaatgc tcctacctgg
    18541 tgaaggagac gaagcaggta aagctggatt tatgaacgag ggcgaaaaac gtataaatcc
    18601 cctgagggcc ttttcgcccc catggaactt aatgacctgg tcgaatccct gagaaccttt
    18661 ccaggcgtga ccaggaagaa gagcatatca tcggtcatca atttctttcc caaacaggct
    18721 tccaccaaga tcttggcgtc ctatggagag gatgccgcgg tcgtggaaca ggatgataag
    18781 ttgctattgc tggcggccga cgggatcatg cccgccctga tgcgggccaa tcccttcttc
    18841 gccggttatt acgcggtcct ggtgaacatt cacgacatcg ccgccatggg cggggtaccg
    18901 atagccatgc tagacatact atcggtcaag gacaaccggg tgtgctccca ggtcatgaaa
    18961 ggcatggaat ccgcggtgaa gaagttcggg gtgcctatcg tcggtggaca tacccatccg
    19021 gattgcgatt acgatgccat agacatcgcc attataggca ctgccgagaa agggcaggcc
    19081 atttatagcc acacagcgca agctggtgac gacgtcatcg tgggcatgga cctggacgga
    19141 tattacccag acgcgctgcc gtacgcctgg gacaccactt cccgcaagga agcgcccttg
    19201 ctgcgaaggc agatgctgat catgaacaag atcgccaagc aaggcctcgt tcgttccgga
    19261 aaggacatca gcaaccccgg gacgttaggc acgctaggaa tgctcctgga gaccagtggt
    19321 aagggagcga tcgtcgatgt agaccgcata ccccgtccgc aaggcgtgga actggtgcaa
    19381 tggttgaaat cgtaccaagg atgcggctat gtggtcacct gcgatcccgc caactctcaa
    19441 aaggtcgtgg aaatgtacgc cacggtggga gttaccgggg cggtcatcgg caaggtgacc
    19501 gatgaaccca agttgatagt caatcagggc gcaaagagcg caatcatgtt cgatttcgat
    19561 aaggacgtca tcactggctg caagcccaca tccaccgtgg gatgggaatc cgtggaaatg
    19621 ggaaaataag gtgctaggcc acgaaggttg ccgcccgaac cgatagaggt tgaccgatca
    19681 ccgactcaac cccgctcccc ttcgagcgtc ggtagtccgt ggtaaggctg ttcccgtcag
    19741 ggcctgaccc gttccccacg atcagagcaa gggatgccgc cctccagctg caccgcgatg
    19801 ctgcctccga ccccgtagga cagggcctca gcgccaatga ttgggcctct agcgctccgg
    19861 atacgacgtc ccccgctgtc acccccgcat atcgacgatt acggtgtaca aggacacgcc
    19921 gaacgtcccg gtcaagccta gcgagtggtc ttatcagtcg agcgtattta taaattctgc
    19981 atcgaaaagc ggatatccac tatagccaac atcgtaggat taagttataa atattttatt
    20041 tgtgtttaac attgataaaa tgattttaaa atcaattaat taaaagtgat ttcaaatggg
    20101 ccgcacgaag agtaggaatg gacagatggg cagaaaggag gccatggata aggccttgaa
    20161 ggatggccgt tctcacttcg agtttcggcc cgagacccgc aaattcctct tgtccaactc
    20221 cctcaacatc gccgtgggga tagccctggt catcgctgta tggtggattt tagctgaggc
    20281 catgatctac actcgcggtg ctctgttccc gacgccaccg gagaccttct cagctctctg
    20341 gagcgctcta aacggtgcag aattgaacgg agagaccatc tattatcaca ccggatcttc
    20401 catgctgcgt tgggggatcg ggtacgccat cgcgctcatc atcgggatag cggtcggaat
    20461 atcattcggg accttgagtc gtatatatga tacaggcatg gtctccgtct atgtgataca
    20521 gatgatacct ggcctagcct gggtgcccat cgccatgctc atattcggac tgggagaatc
    20581 ggcgaccatc ttcatcatcc tgatgaccgc catgcccccc atcatcatca acaccgccgg
    20641 cggcatacgc caggtccctc cggtctacac tcgggtggcg ctgatgtccg gcaaggataa
    20701 aatatccctg ttcaccagcg tgttgatccc cgccgcctcc ctgtccataa tcgacgggat
    20761 gcgcatcggc ctcgccaatg gctggagggt gctcatcgcc gcggagatgg tcctgggcgc
    20821 catggtcggc ctcggtgcca ccatatacga ttcccggtac agcctggact tcgtgtccgc
    20881 cttcatatgc atcatcgtga tctgcttcat cggtcttgcc atcgaaaaaa tgttcttcgc
    20941 gggcctggag aacatggtac ggaaccgtct gggtcttgac aaggaggtct gagatgctcg
    21001 cctctctgaa gaacgtgtcc aaggtgttcg ccaatccccg cacgggaaag ggcctggtgg
    21061 cgttgaacga tgtgagcatc caggtcgaga aaggggattt tctctgcctg atcggcccca
    21121 gcggctgcgg gaagagcacc accctgaacc tgctggccgg gttcgagcat cccagcgaag
    21181 gggagctgat gttcaatggt aaacccatca ccggcccctc gccagaacga ggcgtggtct
    21241 tccaggagtt cagcctctat ccctggatga acgtactgca gaacgtggcc ttctcggtaa
    21301 gggcgggcaa ccggtcggaa atggagggga tcgccaggaa atacctggga atggtcggcc
    21361 tcctggactt cgctcacgcc atgcccaacg agctttcggg aggcatgaag caacgggtgg
    21421 ccatagccag gacgctggcc atggacccgg acctcctgct catggacgaa ccttttggtt
    21481 ctctggacga gcagacccgc cgtaagctgg acaacgaagt gctcagccta tgggagggac
    21541 aggggaagac ggtggtgttc gtcactcact gcatcgagga ggccttgatg ctgggcacca
    21601 gggtggtgct gatgtccgcc tcccccggta ggatcaacaa ggaatggaag atcgaaatgc
    21661 cctggcctcg tgacccattg tcgccggaga tgatcgcgct gaagaaggac gtggtcaaga
    21721 gcctgcaggt ctgttcctgc gccaacgggt ccgcccaagg cgttttcata accataaacg
    21781 gtctggaaga atgatatcag gagaagttgg aggtgcgaat gatgaacaag aaaatgctgg
    21841 ccatcgttct ggtgatcgtg gtggtcatcg ccgcggtcgg cgtggcgatc ctgatgatgt
    21901 cttcggatga tggtgagatg gatctgaccg tggcctactc ggagaagatg aactacgaga
    21961 cgttgatggt ggcgaacgac aagggatact tcgacgatgt gggtctgaac gtcacaccag
    22021 ccatcgtcac cggcggcatt caggccgccg aggccatcgt taccggctcg gctgacgtgg
    22081 cggccatggg cgacgcccct gccgtacagc tcatatccaa agggatcggc gccaagataa
    22141 tcggacgcat agccggagcc gaggggatgc atcggatcat ctccgattcg aacctgaccg
    22201 agccagagga cctggagggc aaaaaggtgg ggatgcagca gagctccagc tcgcacggtg
    22261 cgttcctgca gtggtgcaaa gccaatgagg tggacaccga cctcgtgaaa ttcgtttacc
    22321 tcaatcccac ctacctggca gaggcgatgt actccggtca gatcgatgcc atggtaggca
    22381 gtgaaccctg ggccatcaac accgagaacc tgtgcggcga ctcggtgcac gagctgggca
    22441 gctcgtccgg cctgggcagc tcgttcccca ttgtgctcgt ggcttcccat aaggccctca
    22501 cggagaaggg ggaggcccta tcccgcctgc tcgaggccct ggacatggcc aacgaccaca
    22561 tcaacggcga ttggaacgat tccatggaca tatgcgccgc gcacaccggc ctgaccgtcg
    22621 ggaaccaatc caagggcagc ggcctgcagt tcttcgagct gggtttcaac gccaccgacg
    22681 tgcagagcct gaccatgacc gccatgggcc tgatggactt cggcaagatc gacacggtgc
    22741 cgatcataat ggaccatgtg gacctgagct accttccgga ggaatgaaag gttgaggagg
    22801 aacggtcgtc agctgttcat gggttccctt gaaggagagg tccccgaggt tccgccggtc
    22861 ttcctgcggg acctcacctt gggcctcgat gagacggggt atggtacgcc agaggtctgt
    22921 gctgggacct acgatgcgga taagtccgct cggtccgtac tggccctgca tgggcgatta
    22981 ggtcaggacg ccgtcgtcgg ctgtatccat tacgtcgggt tggagatcga ggccctggga
    23041 ggacgggtca agtaccccga taggggaata cctagcgtgg tgaggcatcc cttccaagac
    23101 acgaacgacc cagagttcgt gcttctggac atgcaaaggg acgccccgtt tcccaacgtg
    23161 gctcgcagct accgcctagt tggcgagggg cttgaaggga acgccgccct ggtctgcaac
    23221 atcgaaggac cggtgaccaa ggcctcgctc ctgcgcggaa tggagaacct ggccctggac
    23281 atgttcttcg acaaggacct ggccgccaag tacgtggact tcgccacaga catctccatg
    23341 gagttcctgc aggccgtgaa tgagcaggcc gacctggact gcagctttct ggcctcggcc
    23401 tccgacaatc cggacatctt tggcacggag gctttccagc gcttcaccgt gcccaacctt
    23461 cgccggatca gcgatgcctc ggccgccctg ggccttcctt cgatatttca tccgcatggg
    23521 gacatgagct ccccggagaa cctgccgctg atggacgacg tcatcgctac cggcgtggag
    23581 ggcttccagt tcgcggagag gaacgatcat ctggtgctga gaaaggcctt cggggaaagg
    23641 ataacgctga tgggtgggat cgacgccttc tccactcttc tcctgggacc ggtggagagg
    23701 atcgcgaggg agacagaggt cttcctgaac gacttccggc cctggagcca ttacgttttc
    23761 atgtgctcct gctccctgca caggggcatg cccttggacc acgtggatgc catgatgcga
    23821 agcgttctgg ggttcgctaa gaaagacata tgaaccacgg ggtgccatat gtccgatgca
    23881 tggctccgcc ggacgtttcc gaaaaaccgc cttggctgag gaccaaggta gtgatggcct
    23941 cgggcatggg ggtacggggc gccttggact cctgcggcct gcgcacggtg tgcgactcct
    24001 cccgctgccc caaccttggg gagtgctggg gaaagggtca tgccaccttc atcatcctgg
    24061 gcgaacgatg tacccgttcc tgccaattct gcgccgtgcc ctccggaaca ccgtccgaga
    24121 ccgacccgga cgaggtcgga aacctggccg aggcggtgag gcgcttaagg cttcgtcacg
    24181 tcgtggtcac ctcggtcacc agggacgatc tgccggacgg aggcgccagc atcttcgccg
    24241 aagtggtacg agaggtccgg tggaacaacc ccgggacgac ggtcgaactg ctcatcccgg
    24301 acctgcaggg taaccgtgag gcgttggaga ccatcctgga ggtggccccg gacgtcctag
    24361 gccataacat agagaccgta cgttctatgc agtggataag ggaccgccgg gcttcctacg
    24421 agcgttccct cggagttctg aaaatgacca aggacatctc accgggaacg ctcaccaaga
    24481 gctccctcat gttggggctc ggggagaccc gggaggagct ggtgcaggcg atgaaggacc
    24541 tccgttcggt cggcgttgac ctgctgacct tggggcagta cctgccgccg aaaggttcca
    24601 acttacaggt gcgaagatat gttcctccgc aggagttcga ggagctacat gaccttgcta
    24661 tgggaatggg tttcaaggga gcgagggcgg gacctctggt ccgctcctct tacgatgcgt
    24721 tcgatttgat gatagaagct ggtgcgagaa gatgctgacc gacgatttcg atccgatgaa
    24781 gggagagatg ctgcaaatca tggatgagga tggtaacgtt gactcatcct tgatgccgaa
    24841 actgagcaag gacctccttc tgaaagcgta ccgcaacatg ctgctcaccc gcctggcgga
    24901 tgacaaggcg gtgaagctgc agaggcaagg gcggttagga gcgtatccgc ccagcaaagg
    24961 tcaggaggca agtcagctgg gcccggccat ggccttgaac gataacgatt ggctggtctg
    25021 ggccttccgg gagatggggg cgctgctttg gaagggcgtt ccgctgcaga cgcagtacct
    25081 ctactggatg ggcaacgagc tcggtaacgt ctatccgaac ggcgttcacg ttacgccgtc
    25141 ggtggtaccg gtcggctcgc aggtgccgca cgcggtcgga atagcctacg ccagcaagct
    25201 gaggggagaa aaggacgtca ccctggccta cttcggtgac ggagcgacgt ccgagggcga
    25261 tttccacgag ggactgaact tcgccggggt gttccgaacg gcgaacgtgt tcgtgtgcca
    25321 gaacaatcag ttcgccatat ccacccgtcg caacaagcag agcgcctcgg ccactttggc
    25381 gcagaaggcc gtggcctacg gattcccggg aatactggtg gacggcaacg acgtcctggc
    25441 catgtacgcc gcgaccaagg aggccgtgga ccgggccagg aacggcgaag gccccacgct
    25501 gatcgaatcg tacacctatc gtttgagcga tcatacgacc tcggacgact ggcgcaaata
    25561 ccgttccaag gaggaggtgg ccgaatggga gcgcaaggac cccctgaaga ggttcagatc
    25621 gtacctggtc gctcagaaca tgatcaagga tgatgagccc ttgatgaagg aactgaccga
    25681 catcgtggag agggcggccg ccgaggcgga agccgtacct gctcctaccc gttcggacgc
    25741 cttcgtgcac acctacgccg agatgcctcc ttacctcaga gggcaaatgg gaggtggcgg
    25801 gaaatgatga tgaacatggt gcaggccatc aattccgccc tatccatgga gatggagcgc
    25861 gatccgtcgg tcgtcgttct tggtgaggac gtcggcgtgg acgggggcgt gttccggctg
    25921 acggacggcc tcatcgacaa gttcggtgag gctcgggtca tagatacacc gttagctgag
    25981 gcgggcatcg ccggggtggc catcggaatg gccttgaacg gactgaggcc ggtggccgag
    26041 atacagttca tgggattctc ctacctgaca ttgaaccaga tgatcaatca cgccgcccga
    26101 atgcgcaacc ggaccagggg gcgcctcacc gtgccgatgg tgctgcgcat gccctatggg
    26161 gcgggagtta aggcgctgga gcatcactcg gagagcaccg aggcgctcta cgcgcagata
    26221 ccgggactta aagtggtagt accttccacc ccgttggagg cgaaaggcct gcttacctca
    26281 tcgatacgcg acccggaccc ggtcatattc ctggagccga cgcgatcata tcgcatgctg
    26341 aaggaggagg tgccggacgg cgagtacctg gtgcccctgg gaaaggccag gacggtgcag
    26401 gaaggggacg atgtcacggt gataggttgg ggggccatga taccgctgat ccagagagcg
    26461 gtcgccaacg tccaggcgtc cgtggagatc atcgacctgc gcaccatatc gcccatggac
    26521 tccgagacga tcgtgacatc cgtgaaacgt actggaaggg cggtggtagt tcacgaggcg
    26581 ccgcgctcct tcggggtggg ggcggaaatt gcttcgcgaa tttatgaagg ggcgatattg
    26641 aagttggagg ctccggtgga acgggtcacc gctccggaca tcacggtgcc tttgccgaag
    26701 ggcgaggacc attactacgt gaacgagcag atgatcagag atgggataga gcgtacgctg
    26761 aggttctagg tgttcatgat ggctactgag ttcaggttcc ctgatctggg ggagggaatt
    26821 gcggaagggg aggtcaagaa gtggctggtg aaggtcggcg ataccgtgac caaggaccag
    26881 tctatcgccg aggtggagac cgacaaggcg gtggtggaga taccttcgcc ggtggccggc
    26941 aaggttcttc gacttgatca ccaggaaggc gaactggtca aggtgggaga ggtgttggcc
    27001 gtcatcggag aggagggcga tgtcgcccca accaatgttc ccccgccaat gacggaggag
    27061 gagcgccctg catcggtgtc agtggtcggc gagcttcccc gggaggaggt ggtggtgacc
    27121 tcggtcactc agaaacggac gtccagggac gtcagcgcca tgccggcggt gcgcaaggcg
    27181 gcccgcgaca ggggcgcgga cataaccgcc gtcacgccca gcggaccaag cggccaggtc
    27241 ctggaatcgg accttggcgc caagaggtca ccccgcaccg ttcccaagtt cgacatctat
    27301 ggttacgtgg accgggtgcc catacgtgga attagacgaa cgaccgccaa gaggatgctg
    27361 gaatcccagc agcggacggc ggccgtgacc agcatggaac aggcggacgt gacgcgcctg
    27421 gtgggcatgc gggaacggtt gaaggctccg atgaaggagc agaagggcgt gaacctgacc
    27481 tacatgccgt tcatcgtcac cgccatcgtc agggcgctga agttgcatcc cctgttgaac
    27541 tcgatgatcg acgacgaacg agaggaactg atcatcaaga agtactacaa catcggagtg
    27601 gcggtggcca tcgacgaggg gctgatggtc ccggtcatca aggccgccga tcagaaatcg
    27661 ctgtgggagc tggccgagga gatcgcttcc ctggccaaga ccgcccagga acgcaagatc
    27721 gacctggccg acctcaaggg cggaacgttc agcattacca attacggcgt cttcggcgga
    27781 acgtacggaa cgccgatcat aaactacccg gagacggcga tactcggcat cggcagaata
    27841 atggacgccc cgctggtggt ggacggcacg ataaaggcgc gcaaggtgct ccccctgtcg
    27901 ctgacgttcg accatcgggc ctacgacggg gcggtggccg ccaagttcct gcgcgacctg
    27961 gtacgtctat tggagaaccc ggaggagctg ctgctcaaca tggacggatg aacgactaac
    28021 gttcaaaggt ccattcatcg ttggcgtagc gcgtcttggc gatcagctca gctctggcca
    28081 attcgtcctg ggtgatatcc ccggagtacc attgccggtt catgatgaag gcattggcca
    28141 tggccgccgt ggcatattcc cagggaacct tcttctgctc gcgtatgctg gtgacccgtt
    28201 ccgccgggtc gcctagcgaa tgggagtcca gcttgtcctt ggggaccttc agcaccgaga
    28261 acatcttgac ccggtccagg tcgtatatca gcgtgccgtg ctgcacgaac atccctttcc
    28321 gacgggattg ggcgctgccg ctgatcttcc tgccgttcac caggacatcg ttgatcggtt
    28381 cgaacgttcc ctcgatgcct aagaacttga gggcgttgac gatcatgccg cctatctccc
    28441 ggtacgcctc gttgatgtcc gcgggcatca tgtcctccgg gcagatgatg ctgtaggtga
    28501 tctcccgatc atggaagacc gctcccccgc cggtgctgcg tcggaccacg tccacaccga
    28561 gtttcttgca gccttccagg tccacgacct cttcgatctt ctggaagcgt ccgacgctca
    28621 ccgccgccgg cttccagccg tagaatcgca tggtcggccc ggccacccgg aatgaaacgg
    28681 cctcggctat cgcctcgtcc agagccatgt tgaaggcggc gctggcctcc tcgtaacgga
    28741 gcaccctcca tctctttctc agcatttcga tcccctcagg aggaatgcca ggtccgacgg
    28801 gccgaagccc accgctcgga ggtcgttctc agataggtaa tcagcgatga tagccccggg
    28861 atcgttggcc ttccagacct tttcttcgac caggaaggat tccaacttcg ccaggccttc
    28921 ttcgggatag aagaagaaat cgccgcttat ccgaatgcga accacctcct cgccctggca
    28981 atcgacgtcc aggaccaggg tcttccctcc ggcgaccctg acccgtctct ccaagatatc
    29041 accccttggc ccaggccacc agtttggcca tgtcgatgcg gccgcagatg gccttgccgg
    29101 tgacctcgtt gtagaaggcc ggaacgccca ggtccccgcc gcaggccggc gctatgatgt
    29161 cggcgagcgt gcgcatcagc ttagcgttct cctcgttgtg ccagacctct aatttttcca
    29221 gcttgatccc cgtttcggcc tcgaactgtt cgaccaccgg cgccagcttg cggcagtggg
    29281 ggcattccct tccatggaac cagataagtc tcttctcgct cattgaacat ccctcttgat
    29341 gaaaagtccg caccagcact cgccggtctc cttgtaggtc ggctgacgaa tgaaattgca
    29401 ggggcagatc aggttcaggt ccttgacgcg atcgccggtg gtgatgcggc aggggcaata
    29461 gcgttgccct ttgcccttca agttctccat gacccctttc gacagcagct ccacctcgtc
    29521 cgccttgtcc gtgagcttca cggtggcgct ctgatcggag aactgcttcc aggcggccag
    29581 taccttggac tggtcgtcca ggggggtgtg gtcctttccg atgatctcca aggcctcgcc
    29641 aaggtccgac agcacgaagg cgttcctcgc tccacaggtg ggacatacct ccggaggctt
    29701 gttccccagg tgaacatcgt tgcagacgtg gcatctccaa agtttcttca tgctatcact
    29761 atggcgtacc gaggcgcaca gataaaatgc ttaaggttca ccacttttcc aagcgcaccc
    29821 tctgctgatc ataacggtcg atgagctttc gtacctcggc gggatggccg aaggggatga
    29881 gcgagaacgg cacgacctcg tccggaacgc ccaccaactt gcgcagccca ttgacccgtt
    29941 cttcgatagg atagatgcct aaccagacag cgcccagacc cagttgcacg gccattatca
    30001 atatgttctc ggtggccgcc gagcaatcct gcacccagaa tccggggtat ttctccagcg
    30061 agggatcgcc gcaaaccaat attgcgccgg cgcactcctt gatcatcttg gcgtagggat
    30121 ggaactccat taccccttca agcgtccgac ggtctctgat caccacaaag tgccaaggac
    30181 gctcgttccc ggcggaaggc gcggacatcc cagcctccag aagctttctg acgtccttct
    30241 cctccacatc ctgcgccgta tagcgccgga cgctcctccg ttcaaggata gggtccttgc
    30301 tcatcgttct tctaaggaaa cccggtggac atataattat cgaggtggta cgaaaaatgg
    30361 atattaatcc tctgtttacg gagattcatg gcggggttcg aagagctcat ctactgcacg
    30421 acgttgctgt tcttcatctt cgacccgttc gctaccgtcc ccatgttcat taccttaacc
    30481 agggaccaga ccccgaagga gcagatggtc agcgccaaca aggcggtgct ggtggccgga
    30541 ctgctcttcg tcatattcgc cctcatcggc gccgagcttc tgggactgtt cagcatctcc
    30601 gtggacgcct tccgcatcgc cggcgggatc gtgctgctcc tgatggccat ggagataatt
    30661 ttctctctcc agctcagcaa gaaggaggag accagcgtgg cctgggtgat catcgccacc
    30721 ccgctgctta gcggaccggg tgtgattacc accgccattc ttctcgttca cctttacggc
    30781 cacttcaccg tgctcatcgc aggagtgata agtttggcca taacctgggg catcatgcgc
    30841 aattccctgc tcatctccca gaaggtgggg aacaatgcca tcgacgtgtt ctccaagatc
    30901 ataggcatgc tgctggcggc catagccgtg gagttcatca tgcgcggttc ggtggactat
    30961 gtccttaaca gcctgagcct gggcttctcc cttctaccgt tgtgatacga ttttgcaaag
    31021 ttttttatca ttcgtgcaca aacgagatgg ctagtgaatc catggccgac tgcaagaagt
    31081 gcgatagcag cctagaagcg atccagttgg atgaaacgcc caagttgcag gtcaggggaa
    31141 gggacgtggg gatcaacgcc ctggacgaca taatgaagga cattcgttcc cgcaacctcc
    31201 aggaaccgga acttggaacc gccctacttg gtgaggtgaa gcgcctggac tacgtaccgc
    31261 cgtcaatgga gaaggactac cgggcggcat tgttgcagga ctatcagcgt cggtttggtt
    31321 gaacatatcc tatcgataat agatgacaaa gtgataacat gaacaagtgc accatctgta
    31381 acagcaatga gcatccggcc aggaccggat cggtgaagat gatggccgtt tcgaaccagg
    31441 tcgatctgcg gctggagatc cacgaggctc acctccgggt gctggacatc tcggtgcacc
    31501 ttcttggcta catcaacgcc taccgcgccc tctcggagct tccggactac ctcggcagaa
    31561 ggaggaccag gtacgccatg gtcctgatca tgcttgacga gatggcgccg ctcatggagc
    31621 tgatgaagga gtgcgagaga ggcatcaccg agcattccgc ggaaatagtg ataaacggtt
    31681 tcttctcccc ccagagcagg caggacagga tggagagggt cctggacgag atcggaaagt
    31741 cggaactgct gttcctgaag gtcaagaaga acctggggcg ggagccttcg gccatcgatt
    31801 tctcggtgtt caaggaccag ttccgccgtg cggacgggaa cctgttcccc gcggtggaga
    31861 gagcgcttcg ttacgattgg agctgcggcg aggatggaat gcctggcgag gagcagatcg
    31921 agatgctgtt cctggccatc gagctcaccg tgcgcggggc ggcggagttc agtcaccagt
    31981 gggctttggc caacgagtac gacatagatt tcaagctgga gacccgttat tcaaaggacg
    32041 gggtcgaccg ccgcaaggaa aagggttatt gggtcaagac gcccctatga gatagcatgg
    32101 ccggcgaaat taaggacgtc agcgacgaac tgttcctgga cctgctgcgc aaggagaagc
    32161 gcttcatagt ggtggagttc tggtctccag gatgttccgt gtgcaaggag gtcgaaccgg
    32221 aggttctgaa ggcccaggcg gagctgggcc cggacgtcct gttcatgcgg ataaacaccg
    32281 accacaacaa gcagctcgct acccggtatc agatcactgg aacgccgacc ttcgtgtact
    32341 tctgcaaggg cgacaagatc ggcggggcca tcggctacat caacgctacg gtgctccgca
    32401 acacggtcaa ggaccttatc cggcattcgg cgtcctgccc ttccgggaag cgcgtaagct
    32461 acgaaatgga tggctacggc tgagctttta tctaataccg catcaatcac cacctcatgt
    32521 ggcaagtcct gtccgtcgag tcctggaagg ctcggggacg ttccgacctg agcaaggtca
    32581 taccgaccgt cagcgacatc atcgagcagg tgcgcaagga aggcgatgcc gcggtgctca
    32641 gacttaccgc ccgcttcgac aaggtggatc ttaccgacct gcgggtgagc agggcggaga
    32701 tcgacgaggc ctattcgaag gtggaccagg aactattgga agccttgaag ttcgccaaga
    32761 tgcgcataga ggcctatcac caaaggcagc gccccgagga tgtgacgctg ttcaaggacg
    32821 gcgagagcta cctgggctgg aagtactctc ccctgggctc catgggcatg tacatcccgg
    32881 gaggaaaggc ctcctacccc agcacggcgc taatgtgcgc cgtcccggcc aaggtggccg
    32941 gggtccgtaa cgtcatagca tgcacgcccc cgccggtcca ccctctaacg ttggtggccc
    33001 tggacctggc gggtgtggac accatattca aatgcggcgg cgcccaggcc atagcggcca
    33061 tgggcatcgg tacgttaagc gtgcccaagg tccagaagat cgtcggacct ggcaacatct
    33121 acgtgacggc ggccaaggtg ctgctgcgtc aggaagtgga gatggacttt ccggccgggc
    33181 ccagcgagat agcggtcctt gccgatggga cggcaagagc ggagaacgtg gccgccgaca
    33241 tcctggccca ggccgagcac gggccggatt cggcctgcgc cctggtcacc gacgatccgg
    33301 cgttggccag gaaggtcgga gagctgctcg aacgacaaat ggaaaagagc gaacgccagg
    33361 acctcatccg gtcatcgctc aagaacagcg gctacatcat ggtgaaggat atgttcgaag
    33421 gtgtggcggt ctgcaatgag ctggcaccgg agcacctgtc catccagacc tccgatcccc
    33481 tctccatctt gccatcgata gaaacggccg gggcgatatt catgggcgat gactcgcccg
    33541 tcgcctgcgg cgattacact accggtacgg accatgtgct gccgaccgcc gggaacgccg
    33601 cggtgcactc cggtctcgac gtgctgcact tcatgaaacg ctcgtcggta cagatgctgg
    33661 acctgaagac cctgaaggac ctggcgccgg cgactataag acttgccgaa acggaaggtt
    33721 tgcaggcgca cgccgaatcg gtgcgcgtgc gtttgaaaaa ataagggatg gtcctagacc
    33781 atcttggtgc cggccgagta gttggcgctc tggttccaga cttccttgac ctcaaagacc
    33841 cagaccccgg acgccttcat ccccatcttg gagagctcgg cgttcatgcc ttcgaatatc
    33901 gggccggacg tcgccagctc ctttaccttg gcccgtatct cgtaggactg catcttgctc
    33961 ccggcgagta tggacaccag ctctcccttg gccttcatcc cttccaggtt cttcccggtg
    34021 cgcttcatca ggatcgctcc gatgaccacg atgtccgggg ccggggcctt gatgcttccc
    34081 gcctggatta tgtgaacgtc tcccttgtca gatttcgtgg ctaggaccct caccgacgca
    34141 gggtcgttga tgacctgcat gacctcattt ggtatggcta ccattttttt tcacctgtac
    34201 cgaaatgaga agcggtcttt ataaaccatt gcaacagaaa aatgacccat gaacatctgg
    34261 ctcccattca agcgccagga cttgatacga ctgctatgac cgcctaggtc attcaaatga
    34321 ccttttggcg ggaatgcaac cccggtcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    34381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    34441 nnnnnnngga cggcaggtcg atcaccgact cggcggcctt gcgcatgaac ggcaggatga
    34501 aatgcccggt gttctcgacg cagatcttga tccccaggga ctcggccaaa gaggaaaggc
    34561 gtccgaagga atcgttcagc gattcgatgt gctcctccag atagcgctcg tacacccaga
    34621 ccttgcgatc tggcaacgtg aagtacaccc cgggattgag gtgcaggttg atcaggaaca
    34681 ccccatgccg ggagccccaa cgtagcgcct cctcacatct gtcgagatgg ccttgtcgca
    34741 ccgagggctg caacgaaccc aggtccagct cgtcgtgcag atggacgctg aagcgcatcc
    34801 cgtccttcat agccgcccgg acgtcccggg tgctgatgtt ctccgggaag gaatagggca
    34861 ggttcatgtt gagctccacg aagtccaggc ccaggtcctt acaaagatcg aggttaggcc
    34921 taagttcctg gtagccgatg agagcaggga tgccgaagaa gctcattcgc acctcgacgc
    34981 ccgagatagt agataaaacg aacgaattca cttgaggagg aggaaccggc gctcctgcct
    35041 tatttcgacc tttccaagga tgcgtttctc cattcgtctc tcccaggacc tgaccatctt
    35101 gaacgtaggg aacagttccg gtatctcgtt ccccaggaag tagtgggtca tgaccccgtt
    35161 ccctctctga aaggtgcgct cctccacctc ctcgcctctg ccgaaacgca tgtcctcctc
    35221 cccgaacacg gagacatata gcgtaccgcc atccttcagc acccgtccga tctccagggc
    35281 cgcctttttt aaagatgccg aatcaagatg tcccaggaca tgcgatgccg ccacgttcgg
    35341 aaaggtctgg tctggaaaag gcaaggcggc gatgtccgct tgcagcaacg gaatttcatg
    35401 cctgcttgcg caggccagca gggccgggcg ggagaagtcc agaccgatga agctggtgtc
    35461 cgcagcaaac gcggtcaggt tcttcccgtt cccgatgccc agttccagca ccaggccgtt
    35521 catcgggatc acctcgtcac agctgccctt ccaaggacgg ccgtccctct ggtagagaag
    35581 gtcccagctt tgcctggagt tcattcccga cgcagctcca gatgatagtg ttcgggatca
    35641 tcgaaagacc tctcaagaac gaagccaggg aaatatgacg gcgccgttcc catcggaacc
    35701 ctctcatgca taggaggacc tctctcggtc tctcgagcct gccagtccac cagagttatc
    35761 ctgcctttcg gccgcagcac gcgcgtaatc tccttcgcca ggcgtccttt gtcctccacc
    35821 tcgtgaaaga cgttcatcag gaccacccgg tccaaggaag cgtcaggtaa cggtatttcc
    35881 ggtagggtgg ccctcaccag gcgtatcctt tcctgtccgt tgtccctttg cctgatcccg
    35941 tcgagcatct cctgctgaaa atccagggcg atcaccttcg cgcccgcgtc cgccagaggt
    36001 atcgacagat atccgatacc ggcgccaaga tcggcgatga cctccccatc cctcggtccg
    36061 atgcgttgca gaattgtttc caccggttgc cgcttccggc gttcttcgtt taccaaacgg
    36121 tgactctcgg aggccgggaa ctgggagggg tgctgatgca tgccatctca tttcccaggc
    36181 ggtatttcaa tcatcctctg cggccggggc gctcttccgg accttcttaa gttccgtgcc
    36241 gccgaccttc ttgagcttgc cattgtccaa ggcccagcgg aagttctcga tctccgactt
    36301 ggcgatggtc accttgtccc cttccttgta ggtgaccttg ttaacccagt ccttgaaggt
    36361 gccgaccgcc ttgtagacgt ccgcttcctc gatgccctgg gcgaacttct gccggccctt
    36421 catctccgaa tacgttccgt tgaacacgga cagctttccg tccttgagct cgccgacctt
    36481 ggtgcacacg gcgtctaaaa ggtaacggtc gtgagtgacg atgatcaggg atccggtgta
    36541 ctcgcgcagg gcgtcctcca ccgcctcctt gctcgggatg tccagatagt tcgagggttc
    36601 gtccaggatc agcaggttct tgtgctgggc cagcaggatc gataacgcca gacgggccct
    36661 ctcccctccg gacagggtgc ttatcggccg ttccacgtcc ttgccggtga gcaacaaccg
    36721 ggcgagtatg gccctggcct ccacggcctg ggtgccgagc gccttcttca tctgctgctc
    36781 ggcggtgatg tccttatcga gctgctcgtg ttcctgcgcg taatagccga ccttcacccc
    36841 gggagatacg taaagttcac cgagataggg gagcttggac tgcaacgtct taagaagggt
    36901 ggtcttcccg ctgccgttcg gcccgaatat gcccaacttg tcgcccttct cgatctccag
    36961 gtccaatttg tccaggacct ttcggttacc gcgagcgacg accaggtcct tggcggtcag
    37021 cacgttcttg cctgacttgc cgagagagta gatgcgcacc tgcagttcct tctcgtcggg
    37081 cggtggctca ggaacctcca cccgctgagc catcttctcc ctggtcttgt gaatggactt
    37141 atacttgtat ttgacgtgaa gttcctcggc caccttctcc tggcgttcct tctccttcgt
    37201 ggccttatcg tgcgcctgcc ataaccgctc gcggtccagg gccttcttct ccatgaatat
    37261 ggaatagttg ccggaatagt gcgtgagctt gccgttctcc agctcgatta tgcgggtggc
    37321 gacgttgtcc aaaaagtacc ggtcgtggga gatgatgatc accgccccct tgagcttcaa
    37381 caactggtcc tccaaccact ccaccgtctc gatgtccaga tggctcgtcg gctcgtccat
    37441 gaatatgaga tcggactgct gggcctgtgc cagtacacgg gagagcatga ccttggtacg
    37501 ttcgccgccg ctcagctcgc ccatggaacc ctgggacttg tgctccaggc cgaaaccttc
    37561 caggatgtcc cgggccttgt ccttggtctg ctggggggcg atccgcacca gttcctcctg
    37621 gatgtgcgag tattcaacgg acagggcgtt ccagtcggta tcggaatcgc cgccggaggt
    37681 catcacctcc tctatctccg ccgccctccg tcgcagcggg gcttcctcct cgctcatgat
    37741 gcccatcgcc gaatcgacgg acgaggaatg atcgacatcc acgaactgtg agaggtagga
    37801 tatcttgctg gtacggaggt tcagcgtgcc cacgtccggc ttgagccggc ccatcagaag
    37861 tttgatcagg gtggattttc cagccccgtt gcggccgacc aggccgatgc ggtcgcccag
    37921 ctcgatctgg atgtccacat ccttgaggac ctccttaggt ccgaacgcct tgcctacgcc
    37981 ctccgccttc aggagcatat caaggctatc gtgccgctga ctttatgcct ttccctagag
    38041 cttcacgatc atgtcgtcct tggataccat caactggccc gggtagcgct cctcgatctc
    38101 ctcccgatcg cgcatggtcg gatacttgta agcgtcgaaa tgagtgagca ccaggcgctt
    38161 ggcgcccgac tgcttcttga tgtccagggc gtcctccggc gtcaggtgag gccaaaggtc
    38221 gctcctctcc ccgctgcgga aggcgctctc cgcgatcaac aggtccacgt tcctggccag
    38281 ctcgacggtg ttcttgcagg gcccggtgtc cgtgcagaag gcgatggaga ccccgtccag
    38341 ttccaggcga tagccgagac agggggacga atgatacaac agtcggctgt ggaagttgaa
    38401 cggccgctcg tgcaaacctt ccttcacctc cagcacctct atgttgtagg ggatcagggc
    38461 tagtggcacc gagtacggtt ccctgagaag ttcgtgcagg gcggtatgcg tgcccattat
    38521 cccgaccacg gtaaccttgt ccttgaaccg gaagcgagcc agctgatgca gcccgatcag
    38581 gtggtccaga tgatggtgcg atagcatgat gacggtcggt ttggagaggt cagcgtaccg
    38641 gtccagcttg tgaagacctc caccggcgtc gagcaccacg ttgaagtcct tggcccgcac
    38701 caggatgctc agggtgttcc cggtgtccgt gtcataccag ccgttcgtgc ccatgaatac
    38761 tacgtccact tgaccaccgg aaataacatg ccaatagcgg acataataat gattcggcgg
    38821 ctccctcgca aactattagg ctaagcgata accttccagt gagagatgga tactaggcac
    38881 gagatcctcc tggagcagat attggaggaa ctgagagagc agaccaaggc cctcaatgag
    38941 cttcggaagc gagtggacga tctggaaagg acctggtcct cgggcctgga cgatgttagg
    39001 cagaccgtca tccccacgga tcggtgatct tgatgacctt tcaacgtaga ttgggaataa
    39061 taggctgtcc ggtattggag gacgagatag tctatctgct aagcggcgac aagggtctaa
    39121 aggacatctt cgtggtgaag gacgaacatt ccgagaagct catcggcaag ctgcgccgga
    39181 agggcattga gatcgttccg accagcgagg agggactgtc cagcctgcca gatagtcaag
    39241 ggcgctccgt cgtggtctgg atgaagtcca tggggttgca cgaggagccc aaggagctgg
    39301 ggaaggaggt cgcccgctcg gccaaggtca tggacgggca ttgcgccacc atcctgcttt
    39361 tctatggact gtgcggaaac gccttcaaga acatgaacct gctctttgag gacgttcgta
    39421 ccccggtcgt aattctaacg gaccagcagg gccagattgt tgacgactgc atcgccgtgc
    39481 ccctgggtgg aacggacgga tacctgcgtt tgcttaaacg ctacgccggt gtcttctaca
    39541 tgacgccggc ctgggccgac aactgggagc tcctgatcaa caagatggag atcgcccgcg
    39601 gcactgagat gggcaacctg gacatgctca agatgctgtt cgagatggct ggttacaacc
    39661 gagtgctgtt gatcgacacc ggactgggag accgcgaggt gctctactcc aaaacgcggg
    39721 agttcagcac cgagttcaac ttcaaagagg tcgttttaga acccgatttc gtcagcaccc
    39781 gggtcagcga cgacgcctat cagaagtgct tggagatgtt ggagaacgga aaaaaggaat
    39841 agggaaaggg ttt
//
LOCUS       DAOPZI010000012        38063 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_957_length_38063_cov_11.194933, whole genome shotgun sequence.
ACCESSION   DAOPZI010000012 DAOPZI010000000
VERSION     DAOPZI010000012.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 38063)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 38063)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38063
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_957_length_38063_cov_11.194933"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(41..466)
                     /locus_tag="PKM11_03815"
     CDS             complement(41..466)
                     /locus_tag="PKM11_03815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47666.1"
                     /translation="MQIKSFETVAIEAKRFSKSGEKVMNIKIENNSAITQISKLDGDV
                     CQIDYRFTANYTGLGYIKIEGHLSVTEIGDKAMDEWRRTNNLPLDDANVVHNAIVGNC
                     MITALLISREIKLPAPIPIPRINMQKKPEIRPSDGVEVA"
     gene            complement(529..634)
                     /locus_tag="PKM11_03820"
     tRNA            complement(join(529..567,598..634))
                     /locus_tag="PKM11_03820"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(599..601),aa:Phe,seq:gaa)
     gene            853..1821
                     /locus_tag="PKM11_03825"
     CDS             853..1821
                     /locus_tag="PKM11_03825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47667.1"
                     /translation="MVERVRSRSTFSASSRSKFIKKDREGVASTIGTIMALLVFLTLI
                     AMFTNTYIPVWMKENERDHMDQVLSQFGDLKGKIDTLIVNAQVTQRPTINMFQPLSLG
                     SDSVPVFTSPTGGFLYLKPMGTYDTGVTVGFNYNYSNSLIKVNEEGGGCVEYYAPNRY
                     FVQQWYGYENGALMVYQKDGVAMRASPSLVFIKNSDSTVNLQFDQVDMIGSNESVSGM
                     GTAGIVIDLIYHDSQTYVVSGATGAESNGPVVLKFTTRYVSALWSHLNQTAAEAGMIS
                     GVSGNYTLTSKLVSAEGRNVYELTLTVFKVNEFTHNRAYVNLDLEY"
     gene            1833..3572
                     /locus_tag="PKM11_03830"
     CDS             1833..3572
                     /locus_tag="PKM11_03830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system ATPase subunit"
                     /protein_id="HNX47668.1"
                     /translation="MENAANEKEEGNGGFRTPKPAEVEWEAIGRAERTRNAYLKLLRR
                     MTPNRASRVKVPVKPALEAVRPGSAITIIPPIEDVNLEVLETYAVVPDYAYVRITYNN
                     GSSEYLYEAIEPRLSLEEQELLEKIKDTLHRTLGYEWEKLTRLDKEEYLRESVDSFIR
                     TRGVKVEKVTKLRIGYYIIRDFVGHGMVDVLMRDDMIEDISCDGHNVPLFVFHGKWES
                     IRSNIIFNNEDELNSFVVTLAQRSGKQISVAAPILDGTTLEGHRIQATYSREVTTRGS
                     TFTIRRFKNRPFTPTDLLRYKTVSPEMMAYLWLGVENGESMILVGGTASGKTSALNSL
                     AIFIPPGAKIVSIEDTREINLPHENWIPGATRTGVGEKDSDGRSAGEIDMYDLVRAAL
                     RQRPNYILVGEVRGKETYIMFQAMATGHSTYSTMHADSVKSMVNRLENPPINCPRILL
                     TALRNVLIQSQVKVGNDMVRRMKQIVEIVGYEPENNELITNTVYEWDPATDRFIFKGH
                     AFLFDKIMEMRSLTNDEMMAEFDRRVEVINYLMKKDIRNHREIWNIVNSYYKDHDKTL
                     TRLRADLAAMEVN"
     gene            3572..4612
                     /locus_tag="PKM11_03835"
     CDS             3572..4612
                     /locus_tag="PKM11_03835"
                     /inference="COORDINATES: protein motif:HMM:NF012694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HNX47669.1"
                     /translation="MAGETDLFTRMDSTKKSYLRTKSAAPKHSKDAGPRVVKLPEGVV
                     PDYVKLSPYQEFCWRTIGKAVVRRMKANPKLELSLMQAHMRLRPEEYTAYVWMTTLIV
                     GVLTGVLGALFGGILIAFLGIGAGMVAATTVAMIVLPIVLTYVVLGSVPGSKAKTRGR
                     DINKRLGAAMSFISAMASADVNIDIIFKELARQPIYGQIKDEAEWITRDTELLGTDIL
                     SAINKASMRSPSIRFQEFLQGVVTTSTSGGQLKPYFLQKADQFEKEAKLEMRAQLETL
                     GLMAETFVTVVVAFPLFLVVIMAIMAIVPGAGGNSDTTILLLYLVVGLMIPFSQFGFI
                     FFIWNTTKESSM"
     gene            4622..5521
                     /locus_tag="PKM11_03840"
     CDS             4622..5521
                     /locus_tag="PKM11_03840"
                     /inference="COORDINATES: protein motif:HMM:NF012694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HNX47670.1"
                     /translation="MADEEMLDIGQLNLKKNDYSRPLFIIGVVGLALCLVIGLIDAIG
                     GFETGLEWIDWVAIGLMALCGPYGFYTSYQRKKILEIESRLPDFLRDVSEGGRFGMTL
                     ADSIKVSARGRYGRLTPEIKRMAAQIDWGVPATDALKLFVDRVDTPLVRRMTTIVIKA
                     NEAGGNVADVLNMVAHDARETLLNRNERSIAMSTYTVVIYVAFAVFLATIYILNSTFL
                     PEMVRAGTSITEGTEGISGNIPVQVQTDVVPQINLIFFISVVIHAFGDGILAGVLQDG
                     RIANGFRHSFIMLLIGLIALRFV"
     gene            5534..7243
                     /locus_tag="PKM11_03845"
     CDS             5534..7243
                     /locus_tag="PKM11_03845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system ATPase subunit"
                     /protein_id="HNX47671.1"
                     /translation="MSESEPLKDLDQLIEKGNLQIERNKKITFKDRYMELVHRVSKSP
                     VRVMVPSSDKSTDQIKGRITEVPKIAESYVDEVEIAKILEPYSYVRIKFDNVSSEYLY
                     EVIEPTLTEDESILLEMLKNSVVLTINPAVGSLDREKESILRAVTDELLKAMGVNLTM
                     ESRERIHYYLRRDFIGYGAIDVMMIDPNVEDCSCDGVRIPLYIFHRKYGSIKSNVRFE
                     SDEELDSFVVWLAQRCGKHISVAEPLLDATIPDGSRLNATLGKHVTKRGSSFTIRRFK
                     DNPFTPVDLLRFKTMSTEMMAYLWISTEFGSSMLVCGGTASGKTTTLNAVLLFIPPQM
                     KIISIEDTRELNLPHENWIPGLTRESFGGRKSASSGSVNMYDLLTAALRQRPQYLMVG
                     EVRGKEAYVVFQAMATGTISYSTFHAEDVQAMVHRMENDPINLPRALITALDIVMLQA
                     QVKVGTKMTRRVKSLTEIVGMDPETGELITNSVFTWNPADDSFNYSGHSYIFEKVRTV
                     KNWSPREIEREWRRRIEILEYMKKIDVTHYRQVAKIISTYYKNPDKVMKEVREVMSQE
                     SRP"
     gene            complement(7284..>9082)
                     /locus_tag="PKM11_03850"
     CDS             complement(7284..>9082)
                     /locus_tag="PKM11_03850"
                     /inference="COORDINATES: protein motif:HMM:NF019325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CARDB domain-containing protein"
                     /protein_id="HNX47672.1"
                     /translation="ITVTVADYPDLIAMDVSFMVNGVAKNEVNLNDDIKVVAAVYNDG
                     ESSAVNFKVVFWLDGVTMVGSVDVASLASKATTAVSMDWDPSTMPNIGQLNEITMLAE
                     VNPDTDANYTHITELDDPLNPNNRATEDLLVKDNRPDLAVTDALVMSNNVNVTTGVLG
                     EKIIVSFNVRNIGLVDATNVKVGVYLDGDVRTVLFEQTRNIAIGGAAQFSVPWTVNVT
                     RDDYQLVINAGVGLDANQTDNQRVVVFTVAAMDPDITISLNKANYAPGDAILINGRIT
                     QGPQKAPIAGLAVTIVLTDATGFPLTASQSTTTDKDGYFYAVLQTPPEKEGSQVVRAY
                     VNSVDGNFTGAASLNIIAPFTPQSIPSYVYLLIVAIVIAVIVIFSIYLYRVGLGRMVE
                     CGNCGALIPEVSKHCPKCGVEFERDTAKCSECGAWIPSQAESCPDCGAKFMTEPLEGE
                     QSSGYIEAMRKQYDEYVDGFRTQAKTALGSKYSEDKFQEWLQTEPSYLPFEEWLRKEE
                     MGRKSGVFPCPACGTLNPRDAKVCNRCGTVFEQAADGAANAKSEEKEKKGTFRRIVRR
                     SGEEKPKAGPAKESPAPVEEASKPDEGGDKPQ"
     assembly_gap    9083..9182
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<9183..12481)
                     /locus_tag="PKM11_03855"
     CDS             complement(<9183..12481)
                     /locus_tag="PKM11_03855"
                     /inference="COORDINATES: protein motif:HMM:NF019325.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CARDB domain-containing protein"
                     /protein_id="HNX47673.1"
                     /translation="MLFTVPGAGQSLSPTENANGDRFIGTDYEESTWNIQGLQNLNGN
                     LTIGAGGTVIVQNGDLNFLSYKTATVDRVHHLTIEDGGKLILINSNLTTGNTLYGAFN
                     ALGVLIRNNGSLSAENSRLEFQGKMLIDNATFIAKSSQVNGPLVTAISSDIQLYDSSI
                     TDIPGTPTSLGEVYAYPFATSYNNTANVDYTVERNPDPLRTVVPDGDAINLTTSGSGY
                     AAIGNLESMTISGFDIGGLVFNEGEAMNVRLMAEYRTSDLFVAGGVPDTFWYYEYLDP
                     TPDQASNMQVFQTYEPSEPALTNTDQVIYQDLTSLSLSSMDISLLTVTFTNSKAESVF
                     IDRVWIEIVLTLPAYNNLYIAGDSELTAVDSMLGVNNMNYSLPEQRKLVVTDTAVANL
                     YGVTIEDEYYKNGSTPFVTVRKDMTFKPTAQGPSDSTTEGSVFDLLTNNNVYYTVPGL
                     GTLHVTAFYTNGYTGMISDAKLVVDYTGSAPYASSAFVQWNVTGKPLQNTSIAIDANY
                     PETLEYDLLQFNTVTLADFSNINIKFSNPDTNNTLFDVIWIVVKTDPTINIYRWVDVS
                     VVGSDGLPVPGAIVNTTNSKGPASYYYNSTLNAEPSQGVLEYLERNSTNFNVTDDNGL
                     VSLPLLTDVINEDWAPNAMAVGAYSVKVTYINETSVPISPAVQDTRFDAFPDLIPQRM
                     SMKFVIDTIVTGGSDWVVTGSEIMSAPLFTWQKNIIVEGNGVLTIKGTSVTMSKNVDT
                     ITQVVVRDNGLLVLENVVLNADFENMKVYLFDNGRLFLNSTTLMPNVGLVMDDSSQVF
                     MDEARIRGAMSAPSTSSVSLVAFNTTFDKAITEFGGNSVAVLTGASIAGTPPVSPKDN
                     AVIHLYSWIVAEVFDGTGLHLLSGVKVEVRKFPSTLYFTGTTNENGTVTVQALSAIVS
                     SKGPQLFGSYVLNATYWYGGDRYDSDKKPIASVLYVSTRNLVRDDAYVRMDLPDAKPD
                     IDPPFYASNITPLRGSEVTLSTVINNIGIVTAYDILVRFSDVSSTGTVIIKNYTIDEL
                     APQSNLTVNVTWTAAYPLGQHNLTVTVDPLNAIPELNEDNNVNYTLVEVLGVPDLAVV
                     KEDVTIGSEAA"
     gene            complement(12693..13979)
                     /locus_tag="PKM11_03860"
     CDS             complement(12693..13979)
                     /locus_tag="PKM11_03860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47674.1"
                     /translation="MSDEQVPIWQVIEEFKEKIKTQEADIKRRKEDLEKWETTLRTKE
                     DQLDQVQQSQVVKDAELKDREAKVVPREEAAARMEKELSALNAELRTREEEMHRLRVD
                     LERRDREVLQQEEQVRSLFQQATEHDASMRQVNQKIALMEEQLHEEVNLVKQSLEATN
                     ARREEMLAKIKVMEEQADALASSKRVTMEEQKRLVDWERSLTEREEALTAREAVLMRR
                     EGTPVPTVESFEGGEAEEKVSESLVNKVEDVSEPMIPAVEPPAEKVGVRERKKAKETE
                     PVPPKAEPEPVNVEAPSKAVEPANKIEPAKVEEVPKAEPEKKPEPAPQLPEIKCPNCG
                     TINDGAAKRCYACGQKLDEESIKALEAKKAERAAAEAQKEAERKATEERKEAERQAEE
                     ARVLAERKEAEEKEADAQPPADEKKPVSIRRIIKRK"
     gene            complement(13997..14695)
                     /gene="gvpD"
                     /locus_tag="PKM11_03865"
     CDS             complement(13997..14695)
                     /gene="gvpD"
                     /locus_tag="PKM11_03865"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gas vesicle protein GvpD"
                     /protein_id="HNX47675.1"
                     /translation="MRDSIPGLEKVFRTDIEAPKVVLVTGPPGSMKTSFCYSVISNYL
                     ERSGEFGLYVTLEETADSHLRNMRSLNIALNDRMEISDFTDLRELDEIVEVDAPTDYM
                     DFIIQMISYQKKKHGDQFTVFALDSLGALYSLMEDVKGIRKKMFYFFKTLRDYNLTCF
                     IVMERGPNTPSELLGDEGFLVDGIIELGLDRTRGKLVRYMRVEKMRACEHSMERHTLE
                     VGDKGLTVLGPTLA"
     gene            complement(14799..18593)
                     /gene="gyrA"
                     /locus_tag="PKM11_03870"
     CDS             complement(14799..18593)
                     /gene="gyrA"
                     /locus_tag="PKM11_03870"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: protein motif:HMM:TIGR01063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HNX47676.1"
                     /translation="MSLNHNKAHKKSARVVGECFVAGTRVLTEKGLIPIEEVSIGERV
                     FTQSGKSQVTELYEMPERELVKVTLENGISVTATSSQLFKVINREFKYEWKEAKDLSP
                     SDHLVMRLDYPDNIPYCKLPDWQGNNKKLNEDLAYIIGHFLSDGHIERMRSDRSNHKG
                     VFNFFSTSTGVIEHIRDVLKKEFNYESTILSQSTNPDEFIPGQPVMHRIRISDTELND
                     YLAESFGIDGSWRAQSKRVPELFYRSPKSVIGALLSGLIDGDGSVHKNRNVVNYSTIS
                     ENLALDVQLLMQQLGAVGKRYTQDKTHETQLVRGYVLKRNGPQISIEIEGRFVKVLSK
                     YVNLYNEIRKERMERIIGSPIKTSSFDRIPYASEAVFSNLSQHHIGGGWFEDSNGKKF
                     RTGISYPSGSKIRYSSDIKTNALGRTQLVEWGIKSKLEMIGSELAPIVNDIVNNNIFF
                     MQVGKIEVAPPEPTYDLQVAGAHEFIADGLVVHNCLGKYHPHGDTAVYDSMVRLAQDF
                     SLRYTLIEGQGNFGSVDGDEAAAMRYTECRMQERAEDMLADLDKDTVEWGDNFDASLK
                     EPLVIPSKLPNLIINGSAGIAVGMATNMPPHNLSEVSDAIVYLVDHPETDVLDLMQFI
                     KGPDFPTGGTIYGLSGIVEAYQTGRGKIKVRAKTHFEEVEHRKRIIVDEIPYQVNKSM
                     LVESIAELVKDKKIEGITDLRDESDRDGMRIVIDLRKDVMEEIILNQLFKHTQMEVTF
                     GIINLALVDNQPRVLTLKEELEIFIEHRHNMVVRRTKFDLAQARKRDHILQGLVKAIS
                     ALDETLHIIRSANSPEEARNGLMARFELDEEQAKAILDMRLQKLTGLELEAIQAEFQE
                     IERMIRDLEDILANESRIMGIIKSETLEMKEKYGDERRTDIVAHALDMDMEDLIPNEE
                     MVLMITQDGYIKRMPLDTYKQQRRGGLGLMGMETKEEDVVTDLFVSMTHDHVMFFTDL
                     GRMYSLKAWQIPVGSRQSKGKPIVNLLPKLEDGEKIMATRPITKLSGDHNLVFATRAG
                     IIKKTPLAAYANIRSRGLIAVGLRDGDKLVDVKLTDGSKEIILATRKGLAARFDEGQV
                     RSMGRPAHGVIGIRPEEGDEVVSMAIVTSDSHLLTVTENGYGKISVVGKKDADDERDT
                     YRKTHRGSKGVITIRTEGRNGDVISVMEVEQDDELILATVNGMVQRIRVADIRVMGRA
                     TQGVTVMDLRESDKVIAVARLAGRKEEQAVQEAEVHEDAGFPEIAEAEEPENEPPEEG
                     ED"
     gene            complement(18826..21240)
                     /gene="gyrB"
                     /locus_tag="PKM11_03875"
     CDS             complement(18826..21240)
                     /gene="gyrB"
                     /locus_tag="PKM11_03875"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HNX47677.1"
                     /translation="MEDASYNANSIQVLEGLEAVRKRPGMYIGSTDTRGLHHLVYEIV
                     DNAIDEVMGGYCNNIDISINQDGSVTVADDGRGIPTGLVPKYERSAVEMVLTVLHAGG
                     KFDRKSYKVSGGLHGVGMSVVNALSEWLEVKVHRDGKEHFLRCERGIVTVPLKEVGPA
                     EGSGTTITFMPDKTIFETVLFEYDTLAEKFKDLAYLNKTAVISFKDEIVGRQDRFHYE
                     GGIIEFVEDLNRSRVKMHEKPIYLMGEKENVIVELSMQYTDAYAENIYSFVNNINTAE
                     GGTHMVGLRSALTRAMNDYAKEHNMLKGIDALSGEDVREGVTAILSIKVPEPQFEGQT
                     KTKLGNSEIKGIVDSLVFEKLTEFLLENPKVATVCIDRCILAAQAREAARKARDLTRR
                     KGILESAALPGKLADCSERDPAKSEIYIVEGNSAGGCFSGDTKVSLLDGRELTFEEMV
                     KEQSEGKEHFCYTIRKNGTIGVEKAINARRTKENAPVIRVTLDNGEVITCTPDHQFMT
                     RDGNYVEARALDAGVSLMPLYKDDEGAVWCPTSEQWLSLGWSGLYSSVQNHKAAAFNH
                     QVVKVEDIGERMDVYDIEVPHSHNFALASGVFVHNSAKMGRNREFQAILPLRGKILNV
                     EKSRLDKILKNQEIHNLITAIGANIGPDCDPSKARYHQIIMMTDADVDGAHIRTLMLT
                     LFYRYMRPLIDAGFIYIAQPPLYKVSKGNKEVYVYDDEALAKAMEEMGSKNVSLQRYK
                     GLGEMNPKQLWETTMDPETRTLRKVTIEDAMKADEMFTILMGDEVEPRRAFIMSHANE
                     VENLDI"
     gene            21501..22769
                     /gene="thiC"
                     /locus_tag="PKM11_03880"
     CDS             21501..22769
                     /gene="thiC"
                     /locus_tag="PKM11_03880"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HNX47678.1"
                     /translation="MSIMFQARAGLSEEIKRAAKAEGADPEWIRRMLATGRAVIPCNP
                     VHSPEPCAIGEGLAVKVNANVGTSRDLPDLEPELEKARVAIRYGADAIMDLSTGGDVD
                     AIRRTILKEVRVPVGTVPIYQEGLRAARRSAVVDMDEDDMFNGIERHAKDGVDFMTVH
                     CGITLESVSRLRNAGRLTDVVSRGGSFLTAWILHNKAENPLYENFDYLLEMANRYEFA
                     LSLGDGLRPGCVADATDRAQIQELIILGELVQRCREAGVQCMVEGPGHVPLSQIQANV
                     LLAKRVCDNAPFYVLGPLVTDIAPGYDHIVGAIGGAVAAFAGADFLCYVTPAEHLSLP
                     DVEDVKEGVIASKIAAHAADLALGRGAERDERMARARKRLDWEAMYDEALDPEKARRY
                     RKRGATAENEGCSMCGDVCAIKLVQKYLEE"
     gene            complement(22771..22867)
                     /locus_tag="PKM11_03885"
     tRNA            complement(join(22771..22826,22849..22867))
                     /locus_tag="PKM11_03885"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22811..22813),aa:Thr,seq:cgt)
     gene            22966..23973
                     /locus_tag="PKM11_03890"
     CDS             22966..23973
                     /locus_tag="PKM11_03890"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX47679.1"
                     /translation="MISEMRLPSAEREEERKGGQASLRELLDTIKKGAFTGYLRTVLT
                     LDGDSSNGVLVFDQGSPTVALYSFKPSGNNSVEMMYRGERAAEFTLGDSIFPDTSITL
                     MKVGDRNALASMIDDYRQDRAPDLTEFIMHFYRDNLRLPSAGEGLDEGTSILELKQAI
                     MKYHREKSLEMAGKRDLRDVELELDEGESYLVEEQSRDFSHGIFVGYLSKGYAGMAIS
                     RTNPRLLRKSYNEIQAELIWLTDHESETERTIPPSLEKIVVVLEEFIEKEDKVVILID
                     DLQYLISSNSFEGALRFIRSLVDRISERQALFLLSIDPASLSAQERSILEREMRLVRE
                     R"
     gene            complement(23970..24953)
                     /locus_tag="PKM11_03895"
     CDS             complement(23970..24953)
                     /locus_tag="PKM11_03895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47680.1"
                     /translation="MPEDRSKANEDEIFEFDCPECGRHIVGETDKCPGCGTEFVIEEV
                     PMIECPSCGVVCSLESETCSSCGKGLVDEGEDEMRLEFPRLVAEVKPLLMLSKDYEVE
                     VGEGRRLIDRAVQAGKQRDLATAVQMVKEARSSIKAALDERLVMEEGNLEKLVTIVSR
                     SGIDPKEVSESLTSLRNLREQGDIEGALQAAAKGRKAAERSSGKYLEANDLVESLSRL
                     IDVCDQFYLDVREAKRMLHEARDAGNHGDWGMMGILARKGREQLMRALPEATKGEMRK
                     AKNQLLDAKAEGKDVRTLVKVLKDAGVAMNRERHDLALEGLLDFKDELKRL"
     gene            complement(25006..25797)
                     /locus_tag="PKM11_03900"
     CDS             complement(25006..25797)
                     /locus_tag="PKM11_03900"
                     /inference="COORDINATES: protein motif:HMM:NF013429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HNX47681.1"
                     /translation="MIRTGPAGYPEGSRSPAEAVRKVRALGLSALEIQFVRNVLYNPG
                     KAEEARLEAQASGVLLSVHAPYYVNLNSPSAETRGKSEDWILRAMRGAEAFGAWMVVV
                     HAATYGQDARGSTGNVVSSLRRVKEAADGESLNAVIGLETMGKRATWGTVPEILEVMD
                     EVPGVLPVVDFAHLQARGPPLDPEGLRALLSSLSDVPRLHCHLSGIEFTAAGERKHLR
                     LGEGLDHLMVLDALRDAGTEATVICESTSPVEDSQIIQRHLSQII"
     gene            25884..26366
                     /locus_tag="PKM11_03905"
     CDS             25884..26366
                     /locus_tag="PKM11_03905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine-specific kinase"
                     /protein_id="HNX47682.1"
                     /translation="MKQYNVPVDKPADANIIVGQSHFIKTAEDLYEAMVNSVPQAKFG
                     VAFCEASGDRLVRVEGNDPELKECALRNALKVGAGHTFFVVMRNAYPVNVLQRIKQVP
                     EVCSIFCATANELELVVAESALGRGIIGVIDGQIPVGAEQDEDVQKRRGFLRKIGYKL
                     "
     gene            26311..27129
                     /locus_tag="PKM11_03910"
     CDS             26311..27129
                     /locus_tag="PKM11_03910"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HNX47683.1"
                     /translation="MKTYKKEEDSSARSDTSYEEPDLYEVLGKYYDVWYEDQIEDTQF
                     YLRLAEQTGGPVLECMCGTGRNIIPMVKEGFQVWGFDRSHSMLDRLTAKMELLDDEVQ
                     SRASVHHADMRTFQCPRQYRLVIVPFNAFLHLLEKEGQEAALRNVAEHLEEGGRFVMS
                     IFNPRLDRPEELVRHRGTRTMLNGEIVSKFEAQTFDQPRQRTTVHYFIDISRQDREMR
                     RVTAQFTIRYISYQEVLDLMKACGLEVLETYGDWNFGPFTKNSDLMVFVAKRSS"
     gene            27126..27902
                     /locus_tag="PKM11_03915"
     CDS             27126..27902
                     /locus_tag="PKM11_03915"
                     /inference="COORDINATES: protein motif:HMM:NF012933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HNX47684.1"
                     /translation="MILDLDHTLGCGQVFRWRKEGDEWKGVVDGRMVTLRQTGDRIGV
                     SGMSEERFARYFRQDDDLKAIYQELGGDALLSSYFTKYRGLRLVRQDPWECMASYVLA
                     TNANIPRIQGMIEKVCRTFGTEMDGYYAFPTPGQLLDRCERSESCGLGYRSKRFIEMA
                     RLVQREEVDFSGLMSMGYEECVQELVRLPGIGPKVADCVSVFSLEHLEAFPVDVRIRK
                     AMAELYGMEGSYRTVNRLSREKFGRWAGYAQEYIYYAYGR"
     gene            complement(27903..28277)
                     /locus_tag="PKM11_03920"
     CDS             complement(27903..28277)
                     /locus_tag="PKM11_03920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX47685.1"
                     /translation="MKIPCELIVWYVLPSIRRELARELVQKHHLSQAEVARKFGVTDA
                     AISQYLKAKRGTNKELENSGRYEDFKREIEISAVRIINGSDIVIETCRICEMVKKSGM
                     LVGIYETQTGLKAPACVCPECE"
     gene            28459..29250
                     /locus_tag="PKM11_03925"
     CDS             28459..29250
                     /locus_tag="PKM11_03925"
                     /EC_number="2.4.2.59"
                     /inference="COORDINATES: protein motif:HMM:TIGR00292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide-dependent adenosine diphosphate thiazole
                     synthase"
                     /protein_id="HNX47686.1"
                     /translation="MEIDEVMVTRKIVERYTEEFLENIDVDVVIAGAGPSSLTAARYL
                     AKAGLRVVIFERKLTPGGGMWGGGMTFPIIVVQESSKSLLEEIDVRLRDAGDGYFTAD
                     SVEASAKLIAAAVSAGARLYNTISVEDVMIRQDSICGVVINSSAVEVAGLHVDPLAIR
                     SKYVIDGTGHPAEVVHVVVRKVGRLNTPTGQIEGEKSMWAEVGEHMTVENTVEVYNNL
                     YVCGMASNAVMGAPRMGPIFGGMLLSGKKVAEMIIAREKKARKKK"
     gene            complement(29252..34609)
                     /locus_tag="PKM11_03930"
     CDS             complement(29252..34609)
                     /locus_tag="PKM11_03930"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HNX47687.1"
                     /translation="MQRVKNKASKQEVLSLLDPLIAEWFDSRFDGLTEPQSYAIPLIH
                     ERKSVLVSSPTGSGKTLTAFTSIINELFKYSKEGKLEDRIYAVYVSPLKALANDINKN
                     LEEPLAQMNELAKQKGYEFPKVRVGVRSGDTSQSERQKQLRKPPHIFITTPESLALVL
                     AAPKFREKFSQVEYIIVDEIHEICDSKRGVHLSITLERLQDLCQRPITRIGLSATLAP
                     IEDIASYLVGCQDGNVRQVELIEVLTKRNLDLEVVCPTEDMTALPYEIVNARMYDGLR
                     DMVNAHQTTLIFTNTRSGTEQVVYKLRERGIESIEAHHGSLAKETRLDVEDRLKRGEL
                     RCVVSSTSLELGIDIGSVDLVCQIGSPKSVAKGLQRIGRSGHSVGKTPKGRMMVLDLD
                     DLVECAVLCRAAHRRNIDRVTIPENALDVLAQTLVGMSLERRWTVDEALVMVRGSYCY
                     RNLSKDDLLQTLRYLGSKDDFEGVYSKLWYDPDEGVFGKKKGARMIYFLNQGTIPEEA
                     SYKVFNERSGLVGDLSEKFVERLSTKDVFILGGRPYEYVRAKGMRVYVRSAPGRKPTV
                     PSWTGEMLPRSFDLSMEIARFRGEMESKLGEPEKEVVQWLMDNFSIDHGSALSLLHYF
                     KEQQASVGIPNQRRLLVEGYLDRQGNSGLIFHLPFGRRVNDAMSRTYAFLLTQRMGCN
                     VSVSISDDSFLLVAPKRIDLSIIPGLIRSGEMRGILRRAVKDSEIFKQRFRHVAARSF
                     MILRNYKGREVSVNRQQVRSQYLLDYLASLESVPVIEETYREVLEDVMDIQKAELIVR
                     SLESGEMVMTTVPYSPIPSPFGHNIVLAGISDIVMMEDRSSLLRELHRKVLSKVLGDE
                     QKFQFEEEKVNAHFRAKRGIAEDKASLLGLMARAGPLHLFREKGRSVYPYCRPTRDQV
                     DEWASELLAEGKVSSVYLDDVYYVATEQLPVYVSLADPAAVKEEEKEALALLDVARTS
                     SELEKLMKQEREEVGKLLRSLESKNLVGRVAYVKGRFSYRARTVERLPKQKAIDSALL
                     RHLDLWAPATADEAAFAMHLPEAEVANALKQMTEGGLLEEGRFIVSEREQYMLKRDHL
                     RLKHGSEVFDHRTVDAYQRSKLERKFASIEECIRFYGEMGLLYDIGRRVENFDLKEWR
                     SLRESGLVLNGRFVRGRVRYVLKEDAPLYVKAYRNFAPNDMDGRVLQRIRDLDGASMR
                     DLVRDMPETKDSIKDSLDRLDRNMYIVRRYEEGEDWSRENFYQAIDVPTYEGDPVDVL
                     VRRFVQAYGPVPAMAVRMSTGLSPFEVDDALDRLNVERITVGETAAEMVMMTEELEAL
                     RSFVPGGEEWSVVSLYDPTAQPRWADTNARFGDSWVFPVLRDGTVVGGVEKWDAGGCV
                     DVRAIDLDEPSYLPHVLKALEQLLSFQASQGLDMVRVKEVLGTPADDVQGDAEKALQD
                     AGYVRMEGMWIRGGVERQFSKEDLLRYTMRRSGLLPKEAYPNVMEGVKRSGGFRGDPA
                     AFARCRVKVPLKRLVEQGLLYSVTGLPEQMMYTTMQYASLFQDAKGRELSDDAKTLVR
                     MLERNLPMPRRAFFERSVLGPSRTQDALREMNKATVVAYGRNNRITLVPPSGLTVREA
                     RLEHLRLLFRNFGVFTAENLSRFLRLEIPMRELRSLLSELIDEGLLAKGFLERGGDAV
                     HWVLKDDLDTLERKLPDRDLVLYQFDNLAHYLYDEVREKCGGMGSLVMRGPQVIGCFR
                     SKHSGKDLTIIDLQGGKEAKAVVKDFVSDLGWTVREKTSKEIPDWEIQEFLGKVMGEE
                     D"
     gene            34738..35553
                     /locus_tag="PKM11_03935"
     CDS             34738..35553
                     /locus_tag="PKM11_03935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47688.1"
                     /translation="MRWFIPGKEGVRMPWKEWEKAIKDPEDMLASMALGEKTYRVCMR
                     AAKLPPQKDARNTITAFAHILHHMLDEIEEDRLLELRYVLQEKWTEKATGIWEPPSEV
                     IWPIGEDLRQDLLSLRHALERVVGPELLRLFWAGMIAAGHDIPLRSAEANTHLSFPLN
                     MLDKMRAENVPPFLDEEEREGMGFLRSELTLSDWTSTDDLEAVLSDQRQFIRQGRLYI
                     DGRLSGGRWFEMKDVRIWRERTLRSCSLLIAFRVMFLASVIAESGPLWPSYPD"
     gene            35588..36613
                     /locus_tag="PKM11_03940"
     CDS             35588..36613
                     /locus_tag="PKM11_03940"
                     /inference="COORDINATES: protein motif:HMM:NF025006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HNX47689.1"
                     /translation="MRKLSVVLLALALVLCSGYIPDRGSSANASGTDIFGQAVNETGA
                     PMPGVEVVVVDVNNPTTTFKAVTGADGRYTMPYTFLSGTYNVTANYINHTANRSYTNV
                     LVNSSQAVRLNFTMLEVLCKLTGYITNGTTPIYQATVTLFNEQRTYSNVSVNPLGKYE
                     ISKVQPGMYTVVASKVGYYASDPQPPVVLIRGETKSLDFVLQEQPADLGGKVEYDGNG
                     LKGVTVKLSSPLFNAETVTDEDGNYTFSQVPSGTYTVTFSKDSFLSRTMNVGLTPFEV
                     RELNVEMEYDTANNTQTFLLGLDLAHSLMVVGLIVSIAVLIIGIYVNYKIRRKPELLD
                     QDDSEQD"
     gene            complement(36599..37171)
                     /locus_tag="PKM11_03945"
     CDS             complement(36599..37171)
                     /locus_tag="PKM11_03945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FumA C-terminus/TtdB family hydratase beta
                     subunit"
                     /protein_id="HNX47690.1"
                     /translation="MRKIASPLDERQARSLRAGDIVSLSGELLTARDEAHLRILELLR
                     KGQELPFQLEDMAVYHCGPIMRQDVGWKVVAAGPTTSARLDRLAPEVIRKCRPRLIIG
                     KGGMSSETAEAMKEVGCAYLAFPGGAAVLAAEALPEVLGVHWSDLGMPEAVWHLRAKD
                     LGPLVVAMDSHGRSLFKEVEDAVKKRSVLL"
     gene            complement(37174..38043)
                     /locus_tag="PKM11_03950"
     CDS             complement(37174..38043)
                     /locus_tag="PKM11_03950"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HNX47691.1"
                     /translation="MYSSSLIEETVVRLLRDAECRLPPDVHAALRHALDIETEEMPRS
                     QLLVILSNVDKASERSVPICQDTGLPVFFVHGRCDERIVEAIRKGVARATEEIPLRPN
                     TVDPVSRENLGSNLGAGMPPMHLDPVDQDHLDIAVLPKGAGSENWSALRMLNPSEGME
                     GVRRFIIECVVKAGSRPCPPVIVGVGIGGTADMACVLAKKALLRKLSSHSDDAILADL
                     ESQLLLQINSLGLGPMGLGGSTTCLGVLVEKSHCHTASLPVAVSLNCWAARKAFARIY
                     PDGRVRFSQEGFD"
BASE COUNT         7419 a        11342 c        11064 g         8138 t
ORIGIN      
        1 gcgccctgac catagggtcg ttcgccctgg accacatccg ctaggcgacc tctacaccgt
       61 cgctaggccg gatctcgggc ttcttctgca tgttgatccg cggtatcggt atcggggccg
      121 ggagcttgat ctccctggat atcaacaggg cggtgatcat gcagttgccg actatggcgt
      181 tgtgcacgac gttggcgtca tctagcggca aattgttcgt tcggcgccat tcgtccatgg
      241 ccttatcccc gatctcggtc acgctcagat gtccctcgat cttgatatat cccaggccgg
      301 tgtagttggc cgtgaatcgg taatcgatct gacacacgtc accgtccagc ttggatatct
      361 gggtgatggc gctgttgttc tcgatcttga tgttcatgac cttctccccg ctcttggaga
      421 agcgcttggc ctcgatagcc acggtttcaa aggatttgat ctgcatttcg gcaccgaatc
      481 ggcatcgagc attaaagaac cttgtcctgc gtggactaaa ataacgaatg gtgccgcagg
      541 ccgggctcga accagcgact tcaagatttc gatcccccgg gcttgcgcct tcggggactt
      601 cagtcttgca ctctcccaac tgagttactg cggcttagcc accccataat tgagcacgat
      661 taaataattt acctatttga ctggtcgaaa atggttcttg accgtcgacg cggaaggcga
      721 gggcacggac gatgtttcga gaggaataaa accgcacaag ccagcagtgc gactggaaat
      781 tctatttttt ctcgacatat ttatatagtc atcacaacgt aaatcatacc tggtaatttt
      841 ggggtaacca gcatggtgga acgcgtcagg tctcgtagta cgttcagcgc gtctagtcgt
      901 tccaaattca ttaagaagga ccgagagggc gtcgcctcca ccatagggac catcatggcc
      961 ctgctcgtgt tccttacctt gatcgccatg ttcaccaaca cctacatccc ggtctggatg
     1021 aaggagaacg aacgggacca tatggaccag gtcctgagcc agttcgggga ccttaagggc
     1081 aagatcgaca cgctcatcgt caacgcccag gtcacccaga ggccgaccat caacatgttc
     1141 cagcccctta gcctgggttc ggacagcgtc ccggtgttca cttcgcccac tggagggttc
     1201 ctctacctga aacctatggg cacatatgac acgggagtga ccgtgggctt caattataat
     1261 tatagcaatt ctctgataaa agttaatgaa gagggagggg gctgtgtgga gtactacgcc
     1321 cccaaccggt acttcgtcca acagtggtat ggctacgaga acggggccct gatggtgtac
     1381 cagaaggacg gagtggccat gcgcgcctcg ccctctttgg tgttcatcaa aaactcggac
     1441 agcaccgtca acctgcagtt cgaccaagtg gacatgatcg gcagcaatga gtcggtctcg
     1501 ggaatgggca cggcaggcat cgtcatcgac ctgatctacc acgactcaca gacctacgtt
     1561 gtcagcggcg ccacgggcgc ggagagcaat gggccggtgg tgctgaagtt caccaccagg
     1621 tacgtgagcg ccctgtggtc gcatctcaac cagacggcgg cagaggcggg aatgatatcc
     1681 ggcgtatcgg gcaactacac gctcacctcc aaattggtga gcgccgaggg acgaaacgta
     1741 tacgaactga cattgaccgt tttcaaggtg aacgagttca cgcataaccg ggcctacgtg
     1801 aacctggacc tggagtactg aggggtgtga ccatggagaa cgctgcgaat gagaaagagg
     1861 aagggaatgg cgggttccgc acaccgaagc cggcagaggt ggagtgggag gccatcggaa
     1921 gggccgaacg gaccaggaac gcctacctca agctccttcg ccggatgacc ccgaacagag
     1981 ccagccgggt gaaggtcccg gtaaagccag ccctggaggc ggtccgacca ggttcagcga
     2041 tcactatcat acctccgata gaggacgtca acctcgaggt gctggaaaca tacgccgtgg
     2101 tgcccgatta cgcttacgta cggatcactt acaacaacgg ctccagcgag tatctttacg
     2161 aggccatcga gccccggctg agcctggagg agcaggagct tctagagaag atcaaggaca
     2221 ccctgcaccg caccctgggg tacgaatggg agaagctcac ccgattggac aaggaggaat
     2281 acctgaggga aagcgtggat tccttcatcc gcaccagagg ggtcaaggtg gagaaggtca
     2341 ccaagttacg cattggctat tacatcatcc gcgacttcgt cggccatggc atggtggacg
     2401 tcctgatgcg cgatgacatg atcgaggata tctcctgtga tggacacaat gtccctctat
     2461 tcgttttcca cggtaaatgg gagagcatac gctccaacat catcttcaac aacgaggacg
     2521 aactgaactc cttcgtggtg accctggccc agcgcagcgg taagcagatc tcagtggccg
     2581 cccccattct ggacgggacg accctggaag ggcaccgcat ccaggccacc tactcccgcg
     2641 aggtcaccac ccgcggttcc acgttcacca tcagaaggtt caagaaccgg cccttcaccc
     2701 ctacggacct attgcgttac aagacggtca gcccggagat gatggcctac ctgtggctgg
     2761 gggtcgagaa cggggagtcc atgatactgg tgggagggac ggccagcggc aagaccagcg
     2821 ccttgaactc cttggccata ttcatccccc cgggggccaa gatagtcagc atcgaggaca
     2881 ccagggagat caacctcccg catgagaact ggataccggg cgccacgcgc accggtgtgg
     2941 gggagaagga cagcgacggg cgttccgccg gggagatcga catgtacgat ctggtgcgtg
     3001 cggccctcag gcagcgtccg aactacatcc tggtgggaga ggtccgcgga aaggagacct
     3061 atatcatgtt ccaggccatg gccaccgggc acagcactta ctccaccatg cacgccgatt
     3121 cggtgaagag catggtcaac aggctggaga acccacccat caactgcccg aggatattgc
     3181 tcaccgctct gcgcaacgtg ctcatccaat cccaggtcaa agtagggaac gacatggtgc
     3241 gccgcatgaa gcagatagtg gagatagtgg ggtatgagcc ggagaacaac gagctcataa
     3301 ccaacacggt gtacgagtgg gaccccgcca ccgaccgctt catattcaag ggccacgcct
     3361 tcctgttcga caagataatg gagatgaggt cgttgaccaa cgacgagatg atggccgagt
     3421 tcgaccgcag ggtggaggtc atcaactacc tgatgaagaa ggacatccga aaccaccggg
     3481 agatctggaa catcgtcaac tcctattaca aggaccacga caagaccctg acccgccttc
     3541 gcgcggattt ggcggccatg gaggtgaact gatggctgga gagaccgacc tgttcaccag
     3601 gatggactcc accaagaagt cctacctgcg caccaagagc gccgcgccca agcactccaa
     3661 ggatgccggg ccgagagtgg tcaagctgcc ggaaggcgtg gttccagatt atgtcaagct
     3721 cagcccgtac caggagttct gttggaggac catcggtaag gcggtcgtca ggaggatgaa
     3781 ggccaacccg aagctggagc tctccctgat gcaggcccac atgcggctga gaccggagga
     3841 gtacaccgcc tacgtgtgga tgaccacgct catcgtgggg gtcctcaccg gggtgctggg
     3901 cgccctcttc ggagggatat tgatcgcctt cctgggcata ggggcgggca tggtggccgc
     3961 gaccaccgtg gccatgattg tattgcctat cgtcctgacc tacgtggtgc tcggctccgt
     4021 gcccggctcc aaggccaaga ccaggggtag ggacataaac aagcgcctgg gggcggcgat
     4081 gagcttcatc tccgccatgg ccagcgctga cgttaacatc gatatcatat tcaaagagct
     4141 ggctcgccag cccatatacg ggcagatcaa ggacgaggcg gaatggatca cccgggacac
     4201 ggagctcctg ggcactgaca tactgtccgc gatcaacaag gcctccatga gaagcccctc
     4261 cattcgcttc caggaattcc tgcagggagt ggtgaccacc tccacctccg gagggcagct
     4321 gaaaccatat ttcctgcaga aggcggacca gttcgagaag gaggccaagc tggagatgag
     4381 ggcccagctg gagaccctgg gactgatggc ggagacgttc gtcaccgtgg tggtggcctt
     4441 cccgctgttc ctggtggtca tcatggccat catggccata gtgccgggtg ccggagggaa
     4501 ctccgacacc accatattgc tactgtacct ggtggtcgga ttgatgatcc cgttctccca
     4561 gttcggtttc atcttcttca tatggaacac gaccaaggag tcgtcgatgt gaggtcctga
     4621 catggctgac gaagagatgt tggacattgg acaactgaac ctcaagaaga acgattacag
     4681 cagaccgctg ttcatcattg gggtcgtagg cctggccctg tgcctggtta tcgggctcat
     4741 cgacgccatc gggggtttcg agaccgggct ggaatggata gactgggtgg ccatagggct
     4801 gatggccctg tgcggcccct acgggttcta caccagctat cagcggaaga agatactgga
     4861 gatcgagtcc cggctgccgg actttctgcg cgatgtgtcc gagggcgggc gtttcggaat
     4921 gaccctggcc gattcgataa aggtctccgc ccgcggcagg tacgggcgcc tgactccgga
     4981 gatcaagcgc atggccgcgc agatagattg gggagtgccc gccaccgacg ccctgaagct
     5041 gttcgtggac cgggtggaca ccccgctcgt gcggcgcatg accaccatcg tgatcaaggc
     5101 taacgaggcc ggtggaaacg tggcggacgt gctgaacatg gtggctcacg acgcccgaga
     5161 gaccctgttg aatcggaacg agcggtccat cgccatgtcc acctataccg tggtcatcta
     5221 cgtggcgttc gccgtgttcc tggcaacgat ttatatcctg aactcgacct tcctgccgga
     5281 gatggtgagg gccggcacct ccatcacgga gggcaccgag ggcatctccg ggaacatccc
     5341 ggtgcaggtg cagacggacg tggtgcccca gatcaatctg atattcttca tatcggtggt
     5401 catccacgcc ttcggggacg ggatactggc cggagtgttg caggacggac gtatagccaa
     5461 cggtttccgt cattccttca taatgttatt gatcggcctg atagcgctga ggtttgtgtg
     5521 atgtaaaatg accatgagcg aaagtgaacc tctgaaggac ctcgaccagc tcatcgagaa
     5581 gggcaatctg cagatcgaga ggaacaagaa gataaccttc aaggaccgct acatggagct
     5641 ggtccaccgg gtgtccaaga gcccggtgcg ggtcatggtc ccctccagcg acaagagcac
     5701 ggaccagatc aaaggaagga tcaccgaggt gcccaagatc gccgagtcct acgtggacga
     5761 ggtggagatc gccaagatcc tggagcctta ttcctacgtc cggatcaagt tcgacaacgt
     5821 ctcctcggaa tacctctatg aggtcatcga accgacgctg accgaggacg agagcatcct
     5881 gctggagatg ctgaagaaca gcgtggtcct gaccattaac ccggccgtgg gcagcctgga
     5941 ccgggagaag gagagcatat tgcgagcggt caccgacgag ctgctcaagg ccatgggcgt
     6001 caacctcacc atggagtcca gggagcgcat ccattactac cttcgccggg acttcatcgg
     6061 ttacggggcc atcgacgtca tgatgatcga ccccaacgtg gaggattgct cctgcgacgg
     6121 ggtgcgcatc ccgctctaca tattccaccg caagtacggc tccataaagt ccaacgtgcg
     6181 cttcgagtcg gacgaggagc tggattcgtt cgtggtctgg ctggcccaac gctgcggcaa
     6241 gcacatatcg gtcgccgagc ccctgctgga cgccaccatc ccggatgggt ccaggttgaa
     6301 cgccacctta gggaagcacg tcaccaagcg cggctcgtcg ttcaccatcc ggcggttcaa
     6361 ggacaacccc ttcaccccgg tggacctgct gcgcttcaag accatgagca cggagatgat
     6421 ggcctacctc tggatctcca cggagttcgg aagctccatg ctggtctgcg gaggcactgc
     6481 cagcggaaag accaccaccc tcaatgcggt gctgctgttc attccgcccc agatgaagat
     6541 catcagcatc gaggacacca gggagctgaa cctgccgcac gagaactgga tacctggact
     6601 gaccagggaa tcgttcggag gccggaagag cgcctcctcc ggctcggtga acatgtacga
     6661 tctgctcacc gccgccctga ggcagcgccc ccagtatctg atggtgggcg aggtgcgtgg
     6721 caaggaagcg tatgtggtgt tccaggccat ggccaccggg accatctcct attccacctt
     6781 ccacgccgag gatgttcagg ccatggtcca caggatggag aacgacccga tcaacctgcc
     6841 ccgggcgctc ataaccgccc tggacattgt catgctgcag gctcaggtga aagtgggcac
     6901 caagatgacc aggcgggtca agtccctgac ggagatagtg ggcatggacc cggagaccgg
     6961 cgagctcatc accaactcgg tgttcacctg gaacccggct gacgattcgt tcaactacag
     7021 cggccactcg tacatattcg agaaggtccg cacggtgaag aactggtccc cccgggagat
     7081 cgagagggag tggcggcgga ggatcgagat actcgagtac atgaagaaga tcgacgtcac
     7141 ccattatcgc caggtggcaa agatcatctc cacctactac aagaacccgg acaaggtcat
     7201 gaaagaggtc cgcgaggtca tgagccagga atcgcggcca taaatttttt ttaattttta
     7261 aaaaaaagaa atgggaaagg ggtttactgg ggtttgtcgc cgccctcatc gggcttgctg
     7321 gcctcttcca ccggagctgg agactccttc gcgggtcccg ccttgggctt ctcctcgccg
     7381 gagcggcgga ctatccgcct gaaggttccc ttcttttcct tctcctcgga cttggcgttc
     7441 gccgctccgt cggcggcctg ctcgaacacc gttccgcagc ggttgcacac cttggcatcg
     7501 cgggggttca gagtaccgca ggcagggcag gggaacacgc cggacttccg gcccatctcc
     7561 tccttcctta gccattcctc gaagggcagg tagctcggct cggtctgcag ccactcctgg
     7621 aacttgtcct cggagtactt gctgccgaga gcggtcttgg cctgggttcg gaagccgtcc
     7681 acgtactcgt cgtactgctt cctcatggcc tcgatgtagc ctgagctctg ctcaccctcc
     7741 agcggttcgg tcatgaactt ggcgccgcag tcagggcagc tctcggcctg ggacgggatc
     7801 caggctccac actcgctgca cttggcagtg tccctctcga actccactcc gcacttcgga
     7861 cagtgcttgg acacctcggg gatcagcgca ccgcagtttc cgcactccac catgcgcccc
     7921 aatcccaccc tgtacaggta gatggagaag atcacgatca ccgcgatcac gatggccacg
     7981 atcagcaggt acacataact gggtatggac tgcggggtga agggggcgat gatgttgagg
     8041 ctggcggcac cagtgaagtt gccgtcgacg ctgttcacgt aggcccttac gacctggctt
     8101 ccctccttct ccgggggggt ctgcaagacc gcgtagaagt agccgtcctt atcggtggta
     8161 gtgctctgcg aagcggtcag ggggaacccg gtggcatcgg tgaggacgat agtgaccgcc
     8221 aggccggcga tcggggcctt ctgaggccct tgggtgatgc gcccgttgat cagtatggcg
     8281 tccccaggag cgtagttggc cttgttcaga gatatagtga tgtccgggtc catggccgcc
     8341 acggtgaaga ccaccacccg ctggttgtcc gtctggttgg catcgagccc gacaccggcg
     8401 ttgatgacca gctgataatc gtcccgggtc acgttgaccg tccagggaac gctgaactgc
     8461 gcggccccgc cgatggcgat gttacgggtc tgctcgaaca ggaccgtccg cacatcgcca
     8521 tccaggtaga cgcccacctt gacgttggtg gcgtcgacca gaccgatgtt cctcacgttg
     8581 aaggacacga tgatcttctc gcccaggacc ccggtggtca cgttgacgtt gttggacatc
     8641 accaaggcat cggtaaccgc caggtccggc cggttatcct tcaccagcag gtcttccgtg
     8701 gcccggttgt tggggttcag cggatcgtcc agctcggtga tgtgagtata gttggcatcg
     8761 gtgtctgggt tgacctccgc cagcatggtt atctcattta actgaccgat gttgggcatg
     8821 gtgctggggt cccagtccat ggagaccgcc gtggtggcct tggaggccag gctggccacg
     8881 tcgaccgaac cgaccatcgt taccccgtcc aaccagaaca ccactttgaa gttcacggcg
     8941 gacgactcgc cgtcgttgta gaccgcggcg accaccttga tgtcgtcgtt caggttgacc
     9001 tcgttcttgg ccacaccatt gaccatgaag ctcacgtcca tggcgatcag gtcaggatag
     9061 tcggccacgg tgacggttat ctnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9181 nncttgccgc ctctgaaccg atggtcacgt cctccttgac cacggccaga tctggaacgc
     9241 cgagcacctc gaccagcgta tagttgacgt tgttgtcctc gttcagctcg ggtatggcat
     9301 tgagcgggtc cacggtcacg gtcaggttat gctgtccgag cggataggcc gcggtccagg
     9361 tcacgttgac cgttaaattg gactgtgggg ccaattcatc gatcgtgtag ttcttgatta
     9421 tgacggtacc ggtggagctc acgtcggaga acctgaccag tatgtcatag gcagtgacta
     9481 tcccaatatt gttgatgacg gtggacaggg tcacctcgct tccccggagc ggggtgatgt
     9541 tggacgcgta gaacggagga tcgatgtccg gcttagcgtc cggcaggtcc atccttacgt
     9601 aggcatcgtc cctcaccagg ttgcgcgtgg atacatacag cacgctggca atgggtttct
     9661 tatccgaatc gtacctatcg ccgccgtacc agtaggtggc gttcagcaca tagctgccga
     9721 acagctgcgg gcctttggag gagacgatgg cactcaaagc ttgcacggtc actgtcccgt
     9781 tctcattggt ggtaccggtg aaatagaggg tggaggggaa tttcctgacc tctaccttca
     9841 cgccggacaa caagtgcaat ccggtcccat cgaacacttc ggcgactatc cagctgtaca
     9901 gatggataac ggcgttgtcc ttaggcgaca ctggaggcgt tcctgcgatg gaagcgccag
     9961 tcagtacggc cacggaatta cctccgaatt cggttatggc tttatcgaag gtggtattga
    10021 aggctaccag cgagacgctg gaagtggagg gggcactcat ggcccccctg atccgggctt
    10081 cgtccatgaa cacctgcgag gaatcgtcca tgaccaggcc gacatttggc atcagggtgg
    10141 tgctgttcag gaacagtcgg ccgttgtcga agaggtagac cttcatattc tcgaagtcag
    10201 cgttcagaac gacgttttcc agtaccagca agccgttgtc ccggaccacg acctgtgtta
    10261 tagtgtcaac gttcttgctc atagtgacgg acgtgccctt gatggtcagt acgccgttgc
    10321 cttccacgat tatgtttttc tgccacgtga acaagggcgc ggacataatc tccgagccgg
    10381 tgactaccca gtcggagccc ccagtcacta ttgtgtcgat aacgaacttc atgctcatcc
    10441 tttgcgggat gaggtccggg aacgcatcga accgggtatc ttggaccgcg ggagagatgg
    10501 gaaccgacgt ttcattgatg taggtgacct tcacgctgta agcgcccacg gccatagcgt
    10561 tgggcgccca gtcctcgttg atgacatcgg tcagcaacgg taggctgaca agaccattat
    10621 cgtcggtgac attgaaattg gtgctgttcc tttccaaata ctcaagcacg ccttgagagg
    10681 gttccgcgtt caaggtgctg ttataataat acgaagcggg acccttggaa ttggtggtgt
    10741 tcacgatcgc gccagggacc ggaagaccgt cactgcccac cacgctcacg tctacccagc
    10801 ggtagatgtt gatggttggg tccgttttaa ctacaatcca tatcacatca aataatgtat
    10861 tgtttgtatc aggattagag aatttaatgt tgatgttgct aaaatcagct aacgtcacag
    10921 tattgaattg taacaaatca tactctaatg tctcaggata attagcgtcg attgctattg
    10981 aggtgttctg gagcggcttt cctgttacat tccattggac aaacgcagat gacgcgtatg
    11041 gggctgatcc ggtgtaatca acgaccaatt ttgcatcaga tatcattcca gtataaccgt
    11101 tggtgtagaa tgcagtaacg tgtagagtgc ccagtccagg aaccgtgtaa tagacattgt
    11161 tgttggttaa taaatcgaat acacttcctt ctgtcgtact atcacttggt ccctgtgcgg
    11221 tcggtttgaa ggtcatgtcc ttccggaccg tcacgaacgg ggttgatccg ttcttgtaat
    11281 actcgtcctc gatcgtcacc ccgtacaggt tggcgacggc ggtgtcggtg acgacgagct
    11341 tccgctgctc aggcagggaa tagttcatgt tgttgacgcc cagcatgcta tcgacggcgg
    11401 tcagctcact gtcgccggcg atgtacaggt tgttgtaggc cggaagggtc agcactatct
    11461 ctatccaaac cctgtcgatg aacacgctct cggccttgct gtttgtaaag gtgaccgtca
    11521 gcagggagat gtccatggac gagaggctca gagaggtcag gtcctgatag atcacctggt
    11581 cggtgttggt cagggccggt tcgctcggct cataggtctg gaacacctgc atgttgctgg
    11641 cctggtccgg cgtggggtcc aggtactcgt aataccagaa ggtatctggg acgcccccgg
    11701 cgacgaatag gtcgctggtg cggtactcgg ccatgagcct gacgttcatc gcctctccct
    11761 cgttgaacac caggccgccg atgtcaaagc cggagatcgt cattgactca aggttcccta
    11821 tggcggcgta gccggaacca ctggtggtca ggttgatcgc gtcgccgtca ggtaccacgg
    11881 tccggagggg gtcggggttc ctctcgaccg tgtaatcgac gttggcggtg ttgttgtaag
    11941 aggtggcgaa cggataggcg taaacctctc ccaggctggt aggcgtgccc gggatatcgg
    12001 ttatggatga atcgtaaagc tggatgtcac tggatatcgc ggtgactaat gggccgttca
    12061 cctggctgct cttggcaatg aaggtagcgt tatcgatgag catcttgccc tggaactcca
    12121 accgggagtt ctcggcgctc agcgatccgt tgttcctgat caggacgccc aaggcgttga
    12181 atgctccgta cagggtgttc ccggtggtca ggttggagtt gatcagaatg agctttccgc
    12241 cgtcctcgat ggtcaagtga tggaccctgt cgacggtggc tgtcttgtac gacaggaagt
    12301 tcaggtcacc gttctgcacg atgaccgttc ccccggcccc tatggtcagg ttgccgttca
    12361 agttctgcag cccttggatg ttccaggtgc tctcctcata gtccgtgccg atgaaccggt
    12421 caccattcgc gttctcggtg ggggacagag actgtccagc accaggaact gtgaacagca
    12481 acagtcctgc gaaagacgag aatagcatac accagacgat tagcaagctc aatgcctttg
    12541 atgccccgac cccaattttc atagacccac cttgcagacg tccttttaat tacgccaggt
    12601 aaaatagaat gttctgatta taaataaata tgtttacctg gatgctaacc agggggcatg
    12661 ctggctactg aaggaaaaac atagagaccg gttcacttcc ttttaatgat cctccttatg
    12721 gacaccggct tcttctcgtc ggccggtggc tgagcgtcgg cctccttttc ctcggcctcc
    12781 ttgcgctcgg ctaacacccg ggcctcttcg gcctggcgct ctgcttcctt cctttcctcg
    12841 gttgccttgc gctcggcctc cttctgggcc tccgcagcgg cgcgttcggc cttcttggcc
    12901 tccaaggcct ttatcgattc ctcatccagc ttctgcccgc aggcatagca acgtttggca
    12961 gccccgtcgt tgatggtccc gcagttggga catttaattt ctggcaactg aggtgccggc
    13021 tcgggtttct tttccggctc cgccttaggg acctcttcga ccttggctgg ctcgatctta
    13081 ttcgccggtt ccacagcctt tgagggtgcc tcgacattca ccggctcggg ttccgcctta
    13141 ggggggaccg gctcggtctc cttcgccttc ttcctttccc ttacccctac cttctcggcc
    13201 ggaggctcga cggccggtat catcggctcg gagacgtcct cgaccttgtt caccagggat
    13261 tcggagacct tctcctcggc ctccccgccc tcgaacgatt cgaccgtcgg caccggggtt
    13321 ccctcccgcc tcatcagcac cgcttcccgg gcggtgaggg cctcctccct ttccgtgagc
    13381 gacctctccc aatccaccag gcgcttctgc tcctccatgg tgacccgctt gctggaggcc
    13441 agggcgtcgg cctgctcctc catgaccttg atcttggcca gcatctcctc ccggcgggcg
    13501 ttggtggcct ccaacgattg cttgaccagg ttcacctcct cgtgcagttg ctcttccatc
    13561 aaggcgatct tctggttgac ctggcgcatg ctagcgtcat gctcggtggc ctgctggaat
    13621 aacgaacgaa cttgttcctc ctgctgaagg acctcccggt cccgccgctc caggtccacc
    13681 cgcaggcggt gcatctcctc ctccctggtg cgcagctctg cgttcaacgc agacagctcc
    13741 ttctccattc gggcggccgc ctcctcgcgg ggaacgacct tggcctcgcg gtccttcagc
    13801 tcggcgtcct tgaccacctg ggactgctgg acctggtcca gctggtcctc cttggtcctg
    13861 agtgtcgtct cccacttctc caggtcctcc ttgcgccgct ttatgtcggc ctcctgggtc
    13921 tttatctttt ccttgaactc ctcaattacc tgccagatcg gaacttgttc gtcggacatc
    13981 gtatcacctc aagatatcag gccagagtgg gtcccagcac cgtgaggcct ttgtccccga
    14041 cctccagggt atgtctttcc atgctgtgct cgcaggcgcg catcttctcc accctcatgt
    14101 agcgcaccag cttcccgcgg gtgcggtcca ggcccagctc tattatgccg tcgaccagga
    14161 acccctcgtc gcccagcagc tcggaggggg tgttaggtcc ccgctccatg actatgaaac
    14221 atgttaagtt gtaatccctc agggtcttga agaagtagaa catcttcttg cgtatgcctt
    14281 tgacgtcctc catgagggag tagagcgccc ccaaggagtc caaggcgaaa acggtgaact
    14341 ggtcgccgtg cttcttcttc tgatagctga tcatctggat tatgaaatcc atgtaatcgg
    14401 tgggggcgtc aacctccacg atctcgtcca gctctcggag gtcggtgaag tccgagatct
    14461 ccatccggtc gttcagggcg atgttcaggc tgcgcatgtt gcgcagatgg ctatcggcgg
    14521 tctcttccaa cgtgacgtac aggccgaact cgcctgatct ctccagatag ttggagatga
    14581 ccgagtagca gaaggaggtc ttcatggatc ccggaggacc ggtcaccaga accaccttcg
    14641 gcgcctcaat gtcggttcgg aagacctttt ccagccctgg tatcgaatcg cgcaacaatc
    14701 gagctcaccg ccgtgcctga catgtccaga tgatactatc cgaaccttgc ccaggcctta
    14761 gatgatattc cgatgggatg ataaagatat tcgcccggtc agtcctcccc ttcctcgggc
    14821 ggttcgttct ctggctcctc ggcctcggcg atctctggga agccagcatc ctcgtggacc
    14881 tcggcctcct gaacggcctg ctcctccttg cgcccggcca gcctggccac ggcgatcacc
    14941 ttgtcgcttt cccgcaggtc catcacggtc acgccctgcg tggccctgcc catgacccgg
    15001 atgtctgcaa ctcgtatacg ctgcaccatg ccgttcacgg tggccaggat cagctcgtcg
    15061 tcctgctcca cctccattac cgagatcacg tcgccgttgc gcccttccgt acggatggtt
    15121 atgacgccct tgctgccgcg atgggtcttg cggtacgtat cccgttcgtc gtcggcatcc
    15181 ttcttcccga ccaccgagat cttgccgtag ccgttctccg tgacggtcag cagatgggaa
    15241 tcggaggtga ctatggccat gctgaccacc tcgtcgccct cctccggacg gatgcctatc
    15301 actccgtgcg ccgggcggcc catggaccgc acctgccctt catcgaagcg ggcggccagg
    15361 cctttccggg tggccaggat tatttccttc gaaccgtcgg tgagcttcac gtcgaccagc
    15421 ttgtcgccgt ccctcaatcc gacggcgatc aggccgcgtg agcgaatgtt ggcgtaggcg
    15481 gccagcggcg tcttcttgat tatcccggcc cgggtggcga acaccaggtt gtggtcaccg
    15541 gacaacttcg ttatcgggcg ggtggccatg atcttctcgc cgtcctccag cttgggaagc
    15601 aggttcacga tgggcttgcc cttggactgg cgggagccga ccggtatctg ccacgccttc
    15661 agcgaataca tcctcccgag gtcggtgaag aacatcacgt ggtcgtgggt catgctgacg
    15721 aagaggtccg tcaccacgtc ctcctccttg gtctccatgc ccattagccc tagtccgccg
    15781 cggcgctgct gcttgtaggt gtctagcggc atccgcttga tgtagccgtc ctgggtgatc
    15841 atgagcacca tctcctcgtt ggggatgagg tcctccatgt ccatgtccag ggcgtgagcg
    15901 acgatgtcgg tgcggcgttc gtcgccgtac ttctccttca tctccagcgt ctcggacttg
    15961 attatgccca tgatgcgcga ctcgttggcc agtatgtcct ccaggtcgcg tatcattctc
    16021 tcgatctcct ggaactcggc ctgtatggcc tccagctcca ggccggtcaa cttctgcagg
    16081 cgcatgtcca gtatcgcctt ggcctgctcc tcgtccagct cgaaacgggc cattaggccg
    16141 ttgcgcgcct cctcagggga gttggccgag cggatgatgt gcagggtctc gtccagagcg
    16201 ctgatggcct tgaccaatcc ttgcaggatg tggtccctct tgcgagcctg ggccagatcg
    16261 aacttggttc gacggaccac catgttgtga cggtgttcga tgaatatctc cagctcttcc
    16321 ttcagcgtga gcacgcgagg ctggttgtcc accagggcca ggttgattat gccgaaggtg
    16381 acctccatct gggtgtgctt gaacagctgg ttgaggatga tctcttccat gacgtccttg
    16441 cgcaggtcga tgactatgcg catgccgtcg cggtccgact cgtcgcgcag gtcggttatg
    16501 ccctcgatct tcttgtcctt gaccagctcg gcgatgctct ccactagcat ggacttgttg
    16561 acctggtacg gtatctcgtc gacgatgatg cgcttgcggt gctctacctc ttcgaagtgg
    16621 gttttagcgc ggaccttgat cttcccgcgc ccggtctggt aggcttccac gataccggag
    16681 aggccgtaga tggtgccgcc cgtcgggaag tcgggacctt tgatgaactg catgaggtcc
    16741 agaacatccg tttcagggtg gtcgaccaga tagacgatgg catccgagac ctcggacaga
    16801 ttgtggggag gcatgttggt ggccattccc accgcgatgc ctgccgagcc gttgattata
    16861 aggttcggaa gcttggacgg gatgaccaat ggttctttta gagaggcgtc gaagttgtct
    16921 ccccattcca cggtgtcctt gtccaggtcg gccagcatgt cctcggcgcg ctcctgcatg
    16981 cggcactcgg tgtacctcat ggccgcggcc tcgtcgccgt cgacggaacc gaagttgcct
    17041 tgaccttcga tcaatgtgta cctcaaagag aagtcctgag ccaggcgtac catcgagtcg
    17101 tagacggcgg tgtcgccgtg cgggtgatat tttcctaaac aattgtgaac tactaaccca
    17161 tcggcgataa actcatgcgc acctgccact tgcaggtcat aggtgggctc agggggcgcc
    17221 acctctatct ttcccacttg catgaaaaat atgttgttgt ttacaatatc attgacgatt
    17281 ggtgctagct cggaaccaat catttctaat ttcgatttta tgccccattc aaccaattgt
    17341 gtgcgcccta aagcattggt tttaatgtcc gaactatatc gtatcttgct cccactggga
    17401 taagatattc ccgtacggaa ttttttacca ttggaatctt caaaccaacc tccaccaata
    17461 tggtgctgag acagatttga gaatacagct tctgaggcgt atggaatcct gtcaaaagac
    17521 gatgttttta ttggagagcc tataatcctc tccattcttt cttttctgat ttcgttatat
    17581 aaattgacat atttagatag tactttgaca aaacgcccct caatctctat tgatatctgt
    17641 ggtccatttc gttttaatac gtatccccta accaattgtg tctcgtgggt tttatcctga
    17701 gtgtatcttt taccaaccgc gcccaattgt tgcattaata attgaacgtc gagggctaag
    17761 ttctcagaga tcgttgaata attgaccaca ttgcgatttt tatgaactga accatcgcca
    17821 tctatcaagc cagatagcaa tgcgccaatg actgattttg gtgacctata gaatagttct
    17881 ggaacacgct ttgattgtgc tcgccagctt ccatctattc caaaactttc tgctaaataa
    17941 tcattcagtt cggtatcaga tatcctaatc cgatgcatca ccggctgacc tggaataaat
    18001 tcatctggat tggtactttg agataagata gtcgattcat aattaaattc ctttttcagc
    18061 acatcccgta tgtgttcgat tacaccagtg gatgtagaga agaagttgaa aaccccctta
    18121 tgattggagc gatcggatcg cattctttcg atatgcccat cagataagaa gtgaccaata
    18181 atgtatgcta gatcctcatt tagcttctta ttattacctt gccagtccgg taatttacag
    18241 tatggtatgt tatctggata atccagtcgc atcacgagat gatcggatgg agacagatcc
    18301 ttagcttcct tccattcata tttaaattca cgatttatca ctttaaaaag ttgagaagat
    18361 gttgcagtta ccgagattcc attctctaaa gtaaccttaa ccagttctcg ttccggcatc
    18421 tcatatagtt cggtgacttg tgatttccca ctctgagtaa agactctttc accgatactc
    18481 acctcctcga tcgggataag acctttttcg gtcagtaccc tcgttccagc cacgaagcac
    18541 tcacccacta ccctggcgct cttcttgtgc gccttgttgt ggttgagcga catgtcgtac
    18601 atcgagtaca gaatgcggcg gtgaactggc ttcagcccgt ccctggcgtc cggcagcgct
    18661 ctggacacta tgacgctcat cgagtagtcg atgtaggact tcttcatctc gttctcgatc
    18721 ggttggagaa ctaccttatg cgtccccgcg tccggtacct tggcgtcccc cgcgttctgt
    18781 tccggggcct gctggttggt gtcttcgtcg gtcattttgg tcacctcaga tgtccaggtt
    18841 ctccacctcg ttggcgtgcg acatgatgaa cgcccgccgc ggttccacct cgtcccccat
    18901 caggatggtg aacatctcgt ccgctttcat agcatcctcg atggtcacct tcctcagcgt
    18961 cctggtttca gggtccatgg tcgtctccca cagctgcttg gggttcattt cgccgagacc
    19021 cttgtacctc tgcaggctga cgttcttgct gcccatctct tccattgctt tagctagggc
    19081 ctcgtcgtcg tagacgtaga cctccttgtt gcccttgctg accttgtaga gaggcggctg
    19141 ggcgatgtag atgaagccgg cgtcgatcag agggcgcatg tagcggtaga acagcgtgag
    19201 catgagcgtc cgtatgtgcg cgccgtccac atcggcatcg gtcatcatga tgatctgatg
    19261 gtaccgggcc ttgctcggat cgcagtccgg acctatgttc gccccgatgg cggtgatcag
    19321 gttgtgtatc tcctggttct tgaggatctt gtccaggcgg gacttttcca cgttgaggat
    19381 cttgcctctg agcggaagta tggcctggaa ctcccggttg cggcccatct tggcactgtt
    19441 atgaacgaat acaccgctcg ccaatgcgaa gttgtggcta tgtgggacct ctatatcgta
    19501 gacgtccatc ctttcgccga tatcttctac tttgacgacc tggtgattga atgctgcggc
    19561 tttgtgattt tggacggacg agtacagtcc ggaccaacct aaagacaacc attgttctga
    19621 ggtaggacac cagaccgcac cttcatcatc cttgtatagg ggcatcaagg agactccagc
    19681 gtccaaagcc cgcgcctcca catagttgcc atccctggtc atgaactggt gatcgggagt
    19741 gcatgtgatt acctcgccgt tgtccagggt cactctgatg accggtgcgt tctccttggt
    19801 tctccgggcg tttattgcct tttcgacccc gatcgtgccg ttcttccgga tggtgtaaca
    19861 gaagtgttcc ttcccttcgg attgctcctt taccatttcc tcgaaggtca gctcccttcc
    19921 atccaagagc gagactttag tatctccaga aaagcatccg ccggcgctgt tcccctcaac
    19981 gatatagatc tcggacttcg ccgggtccct ctcgctgcaa tcggcgagct ttcccggcag
    20041 ggcggcgctt tccaagatgc ccttgcggcg ggtaaggtcc ctggccttcc gggcggcctc
    20101 cctggcctgg gcggccagta tgcatctgtc gatgcacacc gtggcgacct tcgggttctc
    20161 caaaaggaac tcggtcagct tctcgaacac caggctgtcg acgatgccct tgatctcgct
    20221 gttgcccaac ttggtcttgg tctggccttc gaactgcggt tcggggacct tgatgctcaa
    20281 gatggcggtt actccctcgc gcacgtcctc gccgctcagg gcgtcgatcc ccttgagcat
    20341 gttatgctcc ttggcgtaat cgttcatggc ccgcgtcaga gcggagcgca gaccgaccat
    20401 gtgggtgccg ccctcggcgg tgttgatgtt gttgacgaac gagtagatgt tctccgcgta
    20461 agcgtccgtg tactgcatgg acagctcgac gatcacgttt tccttctccc ccatcaggta
    20521 gatgggcttc tcgtgcatct tgacccggct gcggttgagg tcctccacga actcgatgat
    20581 cccaccctcg tagtggaaac ggtcctggcg cccgacgatc tcgtccttga acgatatgac
    20641 cgccgtcttg ttcaggtacg ccaggtcctt gaacttctcc gccagggtgt catactcgaa
    20701 caggaccgtc tcgaagatgg tcttgtcggg catgaaggtg atggtggtgc cgctgccttc
    20761 agcgggtccg acctctttca agggaacggt gactatgccc ctctcgcatc tcaggaagtg
    20821 ttcctttcca tcgcggtgaa ccttcacttc cagccactcg gagagggcgt tcaccacgga
    20881 catgccgacc ccgtgcagac ccccggagac cttgtagctc ttgcggtcga acttgccgcc
    20941 ggcgtgcaga acggtgagga ccatctccac cgccgacctc tcgtacttgg gcaccagtcc
    21001 ggtcgggatc ccacgaccgt catcggcgac cgtgacgctg ccatcctggt tgatggagat
    21061 gtcgatgttg ttgcagtagc cccccatcac ctcatcgatg gcgttgtcca cgatctcgta
    21121 gaccagatga tgaagacctc tggtgtcggt gctgcctatg tacatgcctg gccgcttgcg
    21181 aacggcctcc aggccttcca gcacctgtat gctgttggcg ttgtagctcg cgtcctccat
    21241 attggatacc ctctgtgaat cgatgaatgc gataccgttc ggtcgagacc atgagttcga
    21301 ccgcatccca tccgctgagt aagcgtatgg catctaagta ttaataccat gggattacca
    21361 tctggctata taagcaaacg agggtttttt tggaccagtt ttccttgcct ttctgaccca
    21421 tttcgggagc ggggaaacct tcatatccga ccaggcttga aaggcaacca ataaatcagg
    21481 acaaaggatt ggtggcgacg atgagcataa tgttccaagc gagggccggc ctttcagagg
    21541 aaattaagag ggcggccaag gccgaagggg cggaccccga gtggatcaga cgcatgctgg
    21601 ccaccggtcg cgcggtcatc ccttgcaacc cggtgcattc gccggaacca tgcgccatcg
    21661 gggaaggtct tgccgtcaag gtcaacgcca acgtaggaac gtccagagac cttccggacc
    21721 tggaaccgga gctggagaag gctcgcgttg ccatccgtta cggcgcggac gccatcatgg
    21781 acctcagcac cggcggggac gtggacgcca tacgccggac gatcttaaag gaggtccggg
    21841 tgcctgtggg caccgtcccg atataccagg aggggctgcg cgccgcccgc cgcagcgcgg
    21901 tggtggacat ggacgaggac gacatgttca acggcatcga acgccacgcc aaggacggcg
    21961 tggacttcat gaccgtacat tgcgggatca ccttggagtc ggtctcgcgt ctacggaacg
    22021 ccgggcgcct gacggacgtc gtatcccgcg gcgggtcgtt ccttaccgcc tggatactgc
    22081 acaacaaggc ggagaacccg ctctacgaga acttcgatta cctgctggag atggcgaaca
    22141 gatacgagtt cgctctcagt cttggcgacg gtttgcgccc cggatgcgtg gccgacgcca
    22201 ccgaccgcgc ccagatccaa gaactgatca tcctcggcga gctggtgcag cgctgccgcg
    22261 aggctggagt gcaatgcatg gtcgagggcc ccggtcacgt tcccctctcg cagatacagg
    22321 cgaacgtcct tctggcgaaa cgggtctgcg acaacgctcc gttctacgtg ctaggacctc
    22381 tggtcaccga tatcgcgccg gggtacgacc acatcgtcgg ggccatcggc ggggcggtgg
    22441 ccgccttcgc cggagcggac ttcctttgtt acgtgacgcc ggccgagcat ctctcccttc
    22501 cggacgtgga ggatgtgaag gaaggcgtga tcgccagtaa gatcgccgcg cacgctgcgg
    22561 acctggcgtt ggggcgcggg gcggaacggg acgagcggat ggcccgggcg cgcaagcggt
    22621 tggactggga ggcgatgtac gacgaggcgc tcgatccgga gaaggctcgc cggtaccgca
    22681 agcgtggagc taccgccgag aacgagggct gctcgatgtg cggggacgta tgcgccatta
    22741 agttggtgca gaagtaccta gaagagtaaa tggagccact ggagggtatt gaacccccgg
    22801 cctgcggttt acgaaaccgc cgctctatag cggccccgtg aaggggctac cgctgagcta
    22861 cagtggcgct aggccgacat caaccgctac ggccatttaa aatttgttgt ttccgggatt
    22921 cagacaatta taatatctgg cattcccctt cgtcataagg gtcacatgat ttccgagatg
    22981 cgtctgccgt ccgccgagag agaggaagag cgcaagggag ggcaggcctc gctccgagag
    23041 cttctggaca ccatcaagaa aggcgcgttc accggctatc tgcggaccgt gctgaccctg
    23101 gacggggatt cgtccaacgg cgtgctggtc ttcgatcagg gctcgccgac ggtcgccctg
    23161 tacagcttca aaccctccgg gaacaacagc gtggagatga tgtaccgcgg cgagagggcc
    23221 gcggagttca ccctgggcga ttcgattttc cccgatacct cgataacctt gatgaaggtc
    23281 ggagatcgaa acgcacttgc gtcgatgata gatgattacc ggcaggaccg ggctcccgat
    23341 ctcaccgagt tcataatgca cttctaccgc gacaacctgc gcttgccgag cgccggcgag
    23401 gggcttgatg aaggcaccag catcctggag ctcaagcagg ccatcatgaa atatcatcgc
    23461 gagaaatcgt tggagatggc cgggaagcgc gacctgcggg acgtggaact ggaactggac
    23521 gagggagaga gctacctggt ggaggaacag tcccgggact tctcgcatgg catattcgtc
    23581 ggctaccttt ccaagggcta cgccggtatg gcgatatccc gcaccaaccc gcggcttctg
    23641 cgcaaatcct acaacgagat tcaagccgag ctgatctggc tcacagacca tgagtcggag
    23701 acggagagga ccataccccc gtccctggag aagatcgtgg tggtgctgga ggagttcatc
    23761 gagaaggagg ataaggtggt catactcatc gacgatctgc aatatctcat aagcagcaat
    23821 tcgttcgagg gggcgctgcg cttcatacgg tccttggtgg accgcatcag cgaacgccag
    23881 gccctgttcc ttctttcgat cgacccggcc agcctcagcg cccaggaacg ttcgatattg
    23941 gagcgggaga tgcgtttggt gcgcgagcgt tagagccgct tcagctcgtc cttgaagtcc
    24001 aataggcctt ccaaggccag atcgtggcgc tcgcggttca tcgccacgcc cgcgtccttg
    24061 agcaccttga ccagagtgcg tacgtccttt ccctcggcct tggcgtccag aagttggttc
    24121 ttggccttcc gcatctcgcc cttggtggcc tccggcagcg cccgcatgag ctgctcacga
    24181 ccctttcggg cgagtatgcc catcatgccc cagtcaccat ggttcccggc atcccgggcc
    24241 tcgtgcagca tgcgcttggc ctccctgacg tccaggtaga actggtcgca cacatcgatc
    24301 agccgagata gcgactccac caggtcgttg gcctccaggt acttgcctga agagcgctcc
    24361 gcggccttgc ggcctttggc cgccgcctgc aaggcgcctt cgatgtcccc ctgttcccgc
    24421 aggttgcgca atgaggtgag agactcggaa acctccttcg gatcgatgcc ggagcgggag
    24481 acgatcgtca ccagcttctc caggttcccc tcttccatca ccaatctttc atccagggcc
    24541 gccttgatgg aggaacgggc ctccttgacc atctgcaccg cggtggccag gtccctctgc
    24601 ttgccggcct gtaccgccct gtctatgagg cgccggccct ctccgacctc cacctcgtag
    24661 tccttggata acatcagcag cggcttgacc tcggcgacga gccttgggaa ctccaggcgc
    24721 atctcgtcct cgccctcgtc caccagaccc tttccgcagg acgaacacgt ttcggattcc
    24781 agagagcaga ccacaccgca ggaaggacac tcgatcatcg gcacctcctc gatgacgaac
    24841 tccgtgccgc agcccggaca cttgtccgtc tcgcccacga tgtgccttcc gcactcgggg
    24901 caatcgaact cgaaaatctc atcctcgttg gccttgcttc ggtcctctgg catgtgaccc
    24961 accctgctgg cattagattg ttctgtgctt atttcaagtt gttcattaaa ttatctggct
    25021 caagtgccgt tgaatgatct gggagtcctc cacgggagag gtggattcgc aaattacggt
    25081 ggcctccgtt cccgcatccc ggagggcgtc gaggaccatc agatggtcca acccctcccc
    25141 cagccggaga tgcttcctct ccccggcggc ggtgaactcg atgccgctga gatggcagtg
    25201 cagacggggt acgtccgata acgaactgag cagcgctcgc agcccttccg gatcgagcgg
    25261 cgggcccctg gcctgcagat gcgcgaagtc caccaccggc aggacgccgg gaacctcgtc
    25321 catcacctcc aatatctccg ggacggtgcc ccaggtcgcc ctcttgccca tggtctccag
    25381 gccgatgacc gcgttcaacg attcgccgtc cgccgcctct ttgaccctcc tcagggagct
    25441 gaccacgttg cctgtcgagc ctcgggcgtc ctggccgtag gtggcggcgt gaacgacgac
    25501 catccaggcc ccgaacgctt cggcgccgcg catggccctc aatatccaat cctcgctctt
    25561 ccctcgggtc tccgcggacg gggagttcaa gttcacatag taaggggcgt ggacgctcag
    25621 cagcacgccg ctcgcctggg cctccagccg ggcctcctcg gccttaccgg ggttgtagag
    25681 gacgttgcgc acgaactgta tctcgagcgc gctcagccct agcgcacgaa ccttgcgcac
    25741 ggcctccgcc ggggagcgcg aaccttctgg atatccggcc ggaccggtgc gtatcatgag
    25801 cctgaatcag ataccgccat aaagtaaatt gccgcggcgc acaatgtaaa tatcggggtg
    25861 cggattgtaa gactgggagg agcatgaagc agtacaacgt tccggtggac aagcccgcgg
    25921 atgccaacat catcgtgggg cagtcgcact tcatcaagac cgccgaggac ctctacgagg
    25981 cgatggtgaa ctccgtgccc caggccaagt tcggcgtggc cttctgcgag gcgtccgggg
    26041 accggctggt cagggtcgag ggcaacgatc cggagctcaa ggagtgcgcg ctgcggaacg
    26101 ccctcaaggt cggcgccggg cacaccttct tcgtggtcat gcggaacgct tacccagtga
    26161 acgtgctcca gaggatcaag caggtgcccg aggtgtgctc catattctgc gccaccgcga
    26221 acgagctgga gctggtggtg gcggagagcg ccctgggccg cggaataata ggcgtcatag
    26281 acggacagat accagtggga gctgagcagg atgaagacgt acaaaaaaga agaggattcc
    26341 tccgcaagat cggatacaag ctatgaggag ccggacctct acgaggtcct cggcaagtac
    26401 tacgatgtgt ggtacgagga ccagatagag gatacccagt tctatctgcg cctggcggaa
    26461 cagaccggag gcccggtgct ggagtgcatg tgcggcaccg gccgcaacat cataccgatg
    26521 gtgaaggaag ggttccaggt atggggcttc gaccgcagcc attccatgct ggaccgcctg
    26581 acggccaaga tggagcttct ggacgatgag gtccagtccc gggccagcgt gcaccacgcc
    26641 gacatgcgga cgttccagtg cccgcgccaa tatcgcctgg tcatcgtacc attcaacgcc
    26701 ttcctgcatc tgttggagaa ggagggccag gaggccgccc tgcgcaacgt cgccgagcac
    26761 ctggaagagg gcgggcgttt cgtgatgagc atcttcaacc cccgtctgga ccggccggag
    26821 gagctggtgc ggcatcgtgg gaccaggacc atgctgaacg gggagatcgt ctccaagttc
    26881 gaggcgcaga ccttcgatca gcccagacag cgcaccaccg tacactattt catcgacatc
    26941 tcccgccagg accgggagat gcgccgggtc accgcccagt tcaccatccg ctacatctcc
    27001 taccaggagg tcctggatct catgaaggcc tgtgggctgg aggttctgga gacctacggc
    27061 gattggaact tcgggccctt caccaagaac agcgacctga tggtgttcgt ggccaaacga
    27121 tcatcatgat cctggacctg gaccataccc tgggctgcgg gcaggtcttc cgctggcgca
    27181 aggaagggga tgaatggaag ggcgtcgtcg acggacggat ggtcaccctc cgccagaccg
    27241 gcgaccggat cggcgtttcc ggaatgagcg aggaacggtt cgccagatac ttccggcagg
    27301 acgacgacct gaaggcgatc taccaagagc tgggcgggga cgctctcctt tcttcctact
    27361 ttacgaaata tagaggactg cggctggtcc ggcaggaccc ctgggagtgc atggcctcct
    27421 acgttctggc gaccaacgcc aacatccccc gcatacaggg gatgatagag aaggtgtgcc
    27481 gcaccttcgg caccgagatg gatggttatt acgcctttcc cacgcccgga cagcttctgg
    27541 accgctgcga gcggtcggag tcctgcggcc tgggctatcg gagcaagcgc ttcatcgaga
    27601 tggccaggct ggtccagcgg gaggaggtcg acttttccgg actgatgtcg atgggctacg
    27661 aggaatgcgt ccaggagctg gtcagattac cgggcatcgg tccgaaggtc gccgattgcg
    27721 tgagcgtctt ttccttggag cacctggagg cgttcccggt cgacgtccgc atcagaaagg
    27781 ccatggccga gctgtacggg atggagggca gctatcgaac ggtgaaccga ctgtcccggg
    27841 aaaagttcgg acgctgggcg ggctacgccc aggaatacat ctactacgcg tacggacgct
    27901 gatcactcgc actcggggca gacgcaggcc ggagccttca gaccggtctg cgtttcgtag
    27961 atgccgacca gcatgccgct cttcttgacc atctcgcaga tgcggcacgt ttcgatgacg
    28021 atgtcagaac cgttgatgat tcgtacggcg gatatctcga tctcgcgctt gaagtcctcg
    28081 taccttccgc tgttctccag ttccttgttg gttcccctct tggccttcag atactgggat
    28141 atggcggcgt cggtcacgcc gaacttgcga gccacttccg cctggctcag gtgatgcttc
    28201 tgcactagct ccctggccaa ctcacgcctt atggaaggca gcacgtacca gacgatcagc
    28261 tcgcagggta ttttcatcga cccaaccatc tgcttaacga ttattaaaga ttgtgtaagc
    28321 tatattactg gaggatatgt caagaaacaa ttacgggtga agatagacca tctcgcccgg
    28381 ggcggtcctt cggccatggt ataaataaaa aaatgctctt taccgtgaac attcgttaat
    28441 tgttcaagag gacttattat ggagatcgat gaggtaatgg tcacccgcaa gatagtggag
    28501 aggtataccg aggagttcct ggagaacatc gacgtcgacg tggtcatcgc cggcgcgggg
    28561 ccatcctcgc tcacggccgc gcgctacctg gccaaggccg gtctccgggt ggtcatcttt
    28621 gaaaggaagc tcacccccgg cggaggcatg tggggcggcg ggatgacctt cccgatcata
    28681 gtggtccagg aaagcagcaa gagccttcta gaagagatag atgtgcgcct ccgggacgcc
    28741 ggtgacggtt actttaccgc tgactccgtg gaggcttccg ccaagctcat cgccgcggcc
    28801 gtgtccgctg gcgcgcggtt atacaacacc atatccgtgg aggacgtcat gatccgccag
    28861 gacagcatct gcggcgtggt catcaactcg tctgcggtgg aagtggctgg attgcacgtc
    28921 gatccgctgg ccatccgttc caagtacgtc atcgacggca ccggtcaccc ggccgaggtc
    28981 gtccatgtgg tggttcgcaa ggtcgggcgt ttgaacaccc caactggcca gatcgagggc
    29041 gagaagtcca tgtgggccga ggtcggggag cacatgaccg tggagaacac cgtcgaggtc
    29101 tacaacaacc tctacgtttg cggcatggcc tccaacgcgg tcatgggcgc gccgcgcatg
    29161 ggtcccatat tcggcggcat gctcctctcc ggcaagaagg tggccgagat gatcatcgcc
    29221 cgggaaaaga aggccaggaa gaagaagtag gtcagtcctc ttcgcccatc acctttccga
    29281 ggaactcctg gatctcccag tccgggatct ccttggatgt tttttcccta acggtccagc
    29341 ccaggtcgga gacgaagtcc ttgaccaccg ccttggcctc cttgcccccc tgcaggtcga
    29401 ttatcgtgag gtccttcccg ctgtgcttgg aacggaagca cccgatgacc tgcggtcccc
    29461 gcatcaccag gctgcccatg cccccgcatt tctcccgtac ctcatcgtaa agatagtggg
    29521 cgaggttgtc gaactggtac agcaccaggt cgcggtccgg cagcttcctc tccagggtgt
    29581 ccaggtcgtc cttcagcacc cagtgcacgg cgtccccgcc cctttccagg aaccccttgg
    29641 ccaggagccc ttcgtcgatc agctccgaca gcagggagcg cagttcccgc atggggatct
    29701 ccaggcgcag gaagcgggag aggttctcgg cggtgaagac gccgaagttg cggaacagca
    29761 ggcgcagatg ctccagccgg gcctcgcgca ccgtgagacc ggacggcggc accagggtta
    29821 tgcggttgtt gcgaccgtag gccacgaccg tcgccttgtt catctcccgc agggcgtcct
    29881 gggtccttga cggcccgagc accgaacgtt cgaaaaaggc ccgccggggc atgggcaggt
    29941 tcctctccag cattcgtacc aaggtcttgg cgtcatcgct cagctccctc cccttggcat
    30001 cctggaacag cgacgcgtac tgcatggtgg tgtacatcat ctgctccggc agcccggtaa
    30061 cggagtagag cagcccctgc tccaccaggc gtttcaatgg aacctttacg cggcaacggg
    30121 cgaaggccgc cgggtcgccg cggaaaccgc cgctgcgctt caccccttcc atgacgttcg
    30181 ggtaggcctc cttcggcaag agcccggaac ggcgcatggt gtagcgcagg aggtcctcct
    30241 tgctgaactg ccgttcgacg ccgccgcgga tccacatgcc ttccatgcga acgtatccgg
    30301 cgtcctgcag cgccttttcg gcgtcccctt ggacatcgtc ggccggggta cctagcacct
    30361 ccttcacgcg taccatgtcc aggccctggg aggcctggaa cgagagcagc tgctccagcg
    30421 ctttcaagac gtgaggaagg tacgagggtt cgtccagatc gatggcccgc acgtccacgc
    30481 acccgccggc gtcccacttc tccacgccac cgaccaccgt cccgtcccgc agcaccggga
    30541 acacccagga atccccgaaa cgggcgttgg tgtccgccca gcgcggctgc gccgtcggat
    30601 cgtacaggct caccacgctc cactcctcgc cgccgggaac gaaggagcgc agggcctcca
    30661 gctcctcggt catcatcacc atctcggcgg ccgtctctcc gacggtgatc ctctccacgt
    30721 tcaaccggtc cagggcgtcg tccacctcga acggcgatag gccggtgctc atcctcaccg
    30781 ccatggccgg gaccgggccg taggcttgaa cgaaacggcg caccagcacg tcgaccggat
    30841 ctccttcgta ggtcggtacg tcaatggcct ggtagaagtt ctccctcgac cagtcctccc
    30901 cctcctcgta cctccgcacg atgtacatgt tgcggtccag acggtccagc gagtccttga
    30961 tcgagtcctt ggtctccggc atatcgcgca ccaggtcgcg catgctcgct ccgtcgaggt
    31021 cgcgtatcct ctgcagcacc cttccgtcca tgtcgttggg ggcgaagttg cggtacgcct
    31081 tcacgtagag gggcgcgtcc tccttcagca cgtaacgcac gcggccgcgc acgaagcggc
    31141 cgttgagcac gagtccgctc tcccgcaggg acctccactc cttcagatcg aagttctcca
    31201 cccttcgtcc gatatcatag agcagcccca tctccccgta gaaacggatg cactcctcga
    31261 tgctggcgaa cttccgctcc agcttggacc tctggtacgc gtccaccgtg cggtggtcga
    31321 agacctccga accgtgcttc aggcggagat ggtccctctt gagcatgtat tgctctcgtt
    31381 cgctgactat gaagcgccct tcctccagca gccctccctc ggtcatctgc ttgagggcgt
    31441 tcgccacctc cgcctccggg agatgcatgg cgaacgcggc ctcgtcggcg gtggccgggg
    31501 cccagaggtc caggtgcctg agcagcgcgg aatcgatggc cttctgcttc ggcaggcgct
    31561 ccaccgttcg cgcgcggtag gagaagcgcc ccttgacgta cgccacccgg cccaccaggt
    31621 tcttggactc cagggaacgc agtagctttc cgacctcctc gcgctcctgc ttcatgagct
    31681 tctccagctc cgaggacgtt cgagcgacgt ccagcaatgc caaggcctcc ttctcttcct
    31741 ccttgaccgc cgccgggtcg gccaacgaga cgtacaccgg cagctgctcc gtggccacgt
    31801 agtagacgtc atccagatac accgaggata cctttccttc ggccagaagc tcggaggccc
    31861 actcgtccac ctggtcccgg gtcggacggc agtaggggta aacgcttctc cctttttcgc
    31921 ggaacaggtg cagcggaccg gccctggcca tcaggcccag caacgaggcc ttgtcctcgg
    31981 cgatgcccct cttagcgcgg aagtgggcgt tgaccttctc ctcctcgaac tggaacttct
    32041 gttcgtcgcc caggaccttg gagagcacct tgcggtgcag ctcccgtagc aacgacgagc
    32101 ggtcctccat catcacgatg tccgatattc cggccagcac gatgttgtga ccgaacggcg
    32161 atggtatcgg cgaataggga acggtggtca tgaccatctc ccccgactcc agggaacgca
    32221 cgatgagctc ggccttctgg atgtccatga cgtcctccag cacctcccgg taggtctcct
    32281 cgatcaccgg aacggactcc agggacgcca ggtaatcgag caggtactgc gagcggacct
    32341 gttggcggtt gaccgaaacc tcccgcccct tgtagttccg gagtatcatg aaggagcggg
    32401 cggccacgtg ccggaagcgc tgcttgaata tctccgagtc cttcaccgcc cggcgcaata
    32461 tcccgcgcat ctctccggaa cggatcagcc cggggatgat gctcaggtcg atgcgcttgg
    32521 gggcgaccag caggaaggag tcgtcggata tcgagaccga aacgttgcat cccatgcgct
    32581 gggtgagcag gaaggcgtag gtgcgcgaca tggcatcgtt cacccggcga ccgaacggga
    32641 gatggaatat cagtccgctg ttcccctggc ggtccaggta accttcgaca agaagacggc
    32701 gctggttagg tatccctacc gaggcctgct gctccttgaa gtaatgcaga agggacagcg
    32761 cggagccgtg gtcgatggag aagttgtcca tgagccattg gaccacttcc ttctccggtt
    32821 cgccgagctt cgattccatc tccccccgga agcgggcgat ctccatggac aggtcgaacg
    32881 agcggggcag catctcgccg gtccacgagg gaacggtggg ctttcgcccc ggcgcggaac
    32941 gtacgtaaac gcgcatgccc ttggcccgca cgtactcgta cggtcgtccg cctaagatga
    33001 acacgtcctt ggtgctcagg cgctccacga acttctcgga gagatcgccg accaggccgc
    33061 tgcgctcgtt gaacaccttg taggacgctt cctcggggat ggtcccctgg ttcaggaagt
    33121 agatcatgcg ggcgcccttc ttcttgccga agacgccctc gtccggatcg taccacagct
    33181 tggagtagac accctcgaag tcgtccttgc tgcccagata gcgtagcgtc tgcagcaggt
    33241 cgtccttgga gaggttgcga taacagtacg aaccgcgcac catcaccagc gcctcgtcca
    33301 ccgtccaacg tctttccagg gacatgccga ccagggtttg cgccagcacg tccaaggcgt
    33361 tctccggtat ggtgacgcga tcgatgttgc ggcgatgggc ggcccggcac agcacagcgc
    33421 attccaccag gtcgtccagg tccaggacca tcatgcggcc cttgggcgtc ttgccgacgg
    33481 agtggccgga gcgtccgatg cgctgcagcc ccttggcgac gctcttgggc gaaccgatct
    33541 ggcatacgag atctacggag ccgatgtcta tacccagctc cagggaggtg gaggagacga
    33601 cgcagcgcag ctctcctcgt ttcaaacggt cctccacatc taggcgggtc tctttagcca
    33661 gagaaccgtg atgggcctcg atgctctcga tgcccctttc tctcagtttg taaaccacct
    33721 gctccgtgcc ggagcgggtg ttggtgaata tcaacgtcgt ttgatgcgcg ttgaccatgt
    33781 cccggaggcc gtcgtacatg cgggcgttca ctatctcgta cggaagcgcg gtcatatcct
    33841 cggtcggaca gaccacctcc aggtccaggt tgcgcttggt gagcacctct atgagctcga
    33901 cctgacgcac gttgccgtcc tggcagccga ccaggtacga cgctatgtcc tcgatggggg
    33961 ccagggttgc cgaaagaccg atgcgcgtga tcggccgttg gcagaggtcc tgcagccgct
    34021 ccagggtgat cgagagatgc acgccgcgct tggaatcgca gatctcgtgg atctcgtcga
    34081 cgatgatgta ttcgacctgg gagaacttct cccggaactt gggggcggcc aataccagtg
    34141 ccaaggattc cggggtggtg atgaagatgt gcggcggctt ccgcaactgc ttctgcctct
    34201 ccgattgaga ggtgtcgccg gagcgcacgc ccacgcgcac cttggggaac tcataccctt
    34261 tctgcttggc cagttcgttc atctgggcca gcggttcctc caggttcttg ttgatgtcgt
    34321 tggccaatgc tttcagtggc gatacgtaaa cggcgtagat gcggtcctcc agcttgccct
    34381 ccttggagta cttgaacagc tcgttgatga tggaggtgaa ggcggtgagg gtcttcccgg
    34441 aaccggtggg cgaagacacc agcacgctct tgcgctcgtg tatgagcgga atggcgtagg
    34501 actgcggctc ggtgagaccg tcgaaccgcg agtcgaacca ttccgcgatg agcggatcga
    34561 gcagggagag cacctcctgc ttgctagcct tgttcttcac cctttgcatg ttccaacctt
    34621 cgaaaagcgt attctatcta ttgccgggtt ataattagct tagcatcaga ctatcgaaaa
    34681 tgagggaaca tcgcaggtta taagtcggtc taagtggaaa tgaggaacgg tgcttcgatg
    34741 aggtggttca taccggggaa ggaaggcgtc aggatgccat ggaaggagtg ggagaaggcc
    34801 atcaaggacc cggaggatat gctggccagc atggctctgg gcgagaaaac ctaccgcgta
    34861 tgcatgaggg cggccaagct gcctccgcag aaggacgcca ggaacaccat caccgccttc
    34921 gcgcacatcc tgcatcacat gctcgacgag atcgaggagg accgtctgct cgagctgcgc
    34981 tacgttctgc aggagaaatg gacggagaag gccaccggca tctgggagcc acccagcgag
    35041 gtgatctggc cgataggcga agacctgcgc caggatcttc tttcgctgcg gcacgccctg
    35101 gaaagggtgg tgggtcccga gctgctcagg ctgttctggg cggggatgat cgccgccggg
    35161 cacgacattc cgttgcgttc cgcggaggcc aacacccatc tgtcatttcc gctgaacatg
    35221 ctggacaaga tgcgcgccga gaacgtcccg cctttcctgg acgaagagga aagggaggga
    35281 atgggattcc tgcgctccga actgaccctg agcgactgga cctccaccga cgatctggag
    35341 gcggtgcttt cagatcagcg ccagttcatc cgccagggaa gattgtacat agacggtcgc
    35401 ctgagcggtg gtcggtggtt cgagatgaag gacgtccgga tatggaggga aaggacgttg
    35461 cggtcctgct cgctcctcat agcgttccgg gtgatgttcc tggcctcggt gatagcggag
    35521 agcggccccc tgtggccgtc gtaccctgat taatgttaaa tccatgcttc gaccttgctc
    35581 tactcgcatg cgtaagcttt ccgtggtgct gctggcccta gccctggttc tatgttccgg
    35641 gtacatacct gaccgcggat cgtccgctaa cgccagcggg accgatatct tcggacaggc
    35701 ggtcaacgag accggagcgc ccatgccggg cgtggaggtc gtggtggtag atgtgaacaa
    35761 cccgaccacc accttcaagg ccgtgaccgg ggccgatggc agatatacca tgccttatac
    35821 gttcctgagc ggaacgtaca acgtcaccgc caattacatc aatcatactg ctaaccgaag
    35881 ttatacgaac gtgctggtca acagcagcca ggccgttcga ctgaacttca ccatgctcga
    35941 ggtgctgtgc aagcttaccg ggtacatcac caacggtact accccaattt accaagctac
    36001 ggtcacgctg ttcaacgaac agcggaccta ctccaatgtt tcggtcaacc ctctgggcaa
    36061 gtacgagata tcgaaggtcc agccgggcat gtacaccgtg gtggccagca aggtcgggta
    36121 ctatgcttcc gatccccaac cgccggtcgt tctgatcagg ggcgagacca agagcctcga
    36181 cttcgtcctg caggagcagc cggcagatct gggcggcaag gtcgaatacg acgggaacgg
    36241 cctgaaaggg gtgacggtaa agctgtccag ccccttgttc aacgcggaga cggtgacgga
    36301 cgaggatggt aactacacct tctcccaggt gccctccggg acctataccg taaccttcag
    36361 caaggattcc ttcctgagcc ggacgatgaa cgtgggtctg acgcccttcg aggtccgaga
    36421 gcttaatgtg gagatggaat acgataccgc caacaacacc cagacgttcc ttctaggtct
    36481 cgatctggcg cactccctga tggtcgtcgg cctgatcgtt tcgatcgccg tcctgatcat
    36541 tgggatctac gtcaactaca agatccgccg caagccggag ctgttggacc aagacgactc
    36601 agagcaggac tgatcgcttc ttgaccgcgt cctcgacctc tttgaacagc gaccgtccgt
    36661 gggagtccat ggccacgacc aacggtccga gatctttcgc ccggagatgc cataccgcct
    36721 ccggcatgcc caggtccgac cagtgaacgc ccagcacttc cggtagcgcc tcggcggcca
    36781 gcaccgccgc cccgcccggg aaggccagat aggcgcatcc cacctccttc atggcctccg
    36841 ccgtttcaga ggacatgccg cccttgccga tgataaggcg cggtcggcac ttcctgatga
    36901 cctccggagc caggcggtcc aggcgagcgc tggtggtcgg tccggccgcc accaccttcc
    36961 atccaacatc ctgccgcatt atcggaccgc aatggtagac ggccatatcc tccagttgga
    37021 acggcagttc ctgtcctttt cgtaaaagtt ccaggatgcg aaggtgcgcc tcgtccctgg
    37081 ccgtcagaag ctccccgctg agagagacga tgtccccggc ccgcagggag cgggcctgcc
    37141 tctcgtccaa cgggcttgcg atcttcctca ccttcaatcg aagccctcct gggagaacct
    37201 tacccggccg tccgggtaga tgcgggcgaa ggccttgcgg gcggcccagc aattgagaga
    37261 gacggccact ggcaggctgg ccgtgtggca atgagacttc tcaacaagca caccaaggca
    37321 ggtggtgctt ccccccaggc ccatggggcc caggcccagc gagttgatct gcagtagcag
    37381 ctgagattcc agatcggcga gtatggcgtc gtcgctatga gacgataact tccgaagcag
    37441 ggccttcttt gccaaaacgc aggccatgtc cgccgtgcct cctatgccaa cgcccacgat
    37501 gacgggcggg caggggcggg aaccggcctt caccacgcac tcgatgatga agcgacggac
    37561 gccctccatc ccttccgagg ggttcagcat gcgcagggcg ctccagttct ccgagccggc
    37621 gcccttgggc agtaccgcga tatcgaggtg gtcctggtcc accggatcga ggtgcatggg
    37681 cggcattccc gcgccgagat tcgatcccag gttctcgcgg gataccgggt ccacggtgtt
    37741 cggtcggagc ggtatctcct cggtggctct ggctacccct tttcgaatgg cctctacgat
    37801 gcgctcatcg cagcgcccgt gcacgaagaa cacggggagg ccggtgtcct ggcaaatggg
    37861 cacggaacgt tccgaagcct tgtccacgtt gctcaggatg accaagagct gggaacgcgg
    37921 catctcttcc gtttctatat ccagcgcgtg gcgcagggcg gcgtggacgt ccggcggcag
    37981 gcggcattcg gcgtcacgca gaagcctgac caccgtctcc tcgatcagtg acgacgagta
    38041 catcttgccg tctggattgt cgc
//
LOCUS       DAOPZI010000013        34405 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1177_length_34405_cov_10.471645, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000013 DAOPZI010000000
VERSION     DAOPZI010000013.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 34405)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 34405)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34405
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1177_length_34405_cov_10.471645"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..691)
                     /locus_tag="PKM11_03955"
     CDS             complement(<1..691)
                     /locus_tag="PKM11_03955"
                     /inference="COORDINATES: protein motif:HMM:NF013793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HNX47692.1"
                     /translation="MSFVAAVAGKGGVGKSTVSALLVRILSERDVVLAVDADPNSNLG
                     QKLGTDVPGTVGQVREGLLSKGGQPPRDMSKQEYLKLKLREILAEGHGYDLLTMGRPE
                     GPGCYCYVNNLLRVFVDQLMESYSHVIIDNEAGMEHLSRRTAKEMDLLVLVSDPTAVG
                     VATAVRLSELADELDLQVRRKVLLINGVRSGKENKAEQLAKGTGLEFFLLHDDEVVRD
                     ASSSGIPVKGDE"
     gene            complement(688..1719)
                     /locus_tag="PKM11_03960"
     CDS             complement(688..1719)
                     /locus_tag="PKM11_03960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47693.1"
                     /translation="MAWNCAATGIGSLPHKDPQKALDIVTASMSEVPYWPQMPSLGFG
                     ENMYAQFSFTLPGVKVDAHKKRIIVDLNDYDPEAFYTAVVTDDIEHFAHHKDHFQGLY
                     ALLDRFKGKKLPAVKGQVTGPVSAGLQILDQNGKAAIYDEAYGEIIRRNLNMQAKWQA
                     RKLREISDRPIIFLDEPSLTLIGTPFASISQRQVVDWTDEVLEGVDAIKAMHCCGNTD
                     WPLLLSTSIDMLSFDAYNYAHTVSLFPKEVSAFLDRGGSIAWGLIPNMEDQIAKETVG
                     TLLQRFESYMDLLYRKGMDLDLVLERSLITPQCGLGGLDEAKAERVLELLNGTVEAIR
                     QRYRLGGMS"
     gene            complement(1749..2504)
                     /locus_tag="PKM11_03965"
     CDS             complement(1749..2504)
                     /locus_tag="PKM11_03965"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HNX47694.1"
                     /translation="MNGKKVQEIFGKRAEGYVKSASHADKEVLERVGEMCGDLHDKLA
                     LDVATGTGHVAMHLAPAAGTVIGLDLTRRMLEVAREEAVKRSISNIAWLRGDVRSLPF
                     PDGSFHAVTCRRAPHHFPDINKALKEMARVLKDDGVMVIDDRSVPDDPEVDRTMNHLD
                     LLHDRSHVREYGRREWERMLGETGLRDIEVREYRRHLALSTMTWNAEPSDAKEIERVV
                     SSLSSDLKGRMAVEEADGKLFIDQYYIAIRATK"
     gene            2579..3271
                     /locus_tag="PKM11_03970"
     CDS             2579..3271
                     /locus_tag="PKM11_03970"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47695.1"
                     /translation="MRLITVNRTKPNASIEFYGCPMQCKYCSHTAAQYKDYDLDKIIL
                     AMSDNGIRSVFIGGAEPAVHSREALELIRILKAKGKEVILKTTGHDPDFVAAAKDKVT
                     RFVLELKAPLDEPELLTKLTIYDMEKAKEQQEKLRRTLEIMKGSRVRATLRVIPERYT
                     EDTVERMAKDLKGYVDELHLIQFMSSQNDVGYAGIYNPGPDQETMMRLGRIARKHLPR
                     VKVVGNGFDVIL"
     gene            complement(3261..5177)
                     /locus_tag="PKM11_03975"
     CDS             complement(3261..5177)
                     /locus_tag="PKM11_03975"
                     /inference="COORDINATES: protein motif:HMM:NF036965.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASKHA domain-containing protein"
                     /protein_id="HNX47696.1"
                     /translation="MSPQVTFHPKGRSIEAPVDTNLLEAAILAGVEINSACAGKGVCG
                     RCRVVVEGDVDSQNTPRITEEDRSNGYRLACLSKVKGDCIVFVPEESQLKPMQIVGGK
                     VSTDLKQISPLVRAIYAKLRPPTLQDNDADLERLLKQLGYEPGALEVPLSLLRELPRA
                     IREGEWTVTAFLDGNILVDVLPWNVVSRNFGVSVDIGTTTVALQLVDLSTGEMISQVS
                     DYNRQLMYGEDVLARIMYSEDHGLERLRHTIVDTINHMLARVCNTGDVCVGKGKKVCA
                     EEIMAVSVAGNTTMMHMLLGLDPKCIRYAPYTPVTNLSPRINASELGLNVNPRASVHL
                     VPGRASYVGGDVVADVVASGMARNEGISLLIDVGTNGEIVLGNNDWLLACSASAGPAF
                     EGGEVCHGMRAGDGAIEKVSLKGGVEYSTIGKVRPKGICGSGLIDLLAQLFLTGVLDK
                     KGHLQPSERVRDGEFGKEYVLVYSKDVERDGYDVKATGMSCCPTDKVERRRDITVTEE
                     DIANIVRTKASLYAAAEVLLDTAGIDFTDLERVYIAGGFGHHIDLDNAVAIGLLPDLP
                     RERFTFLGNASLDGAKLCLLSQEKREEALAAHRAMTYVELSTDQRFFDRFSSASFLPH
                     TDLSRFPSIEQIRG"
     gene            5258..6178
                     /locus_tag="PKM11_03980"
     CDS             5258..6178
                     /locus_tag="PKM11_03980"
                     /inference="COORDINATES: protein motif:HMM:TIGR01297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HNX47697.1"
                     /translation="MSMEHGHDHRGGSTKMLTYALVITAAFALVELVGGLLSGSLALL
                     SDAGHMFTDVLALGLSLGASLVAARQATERHTYGFLRAEILVALVNGIALVGISLLVI
                     HEALGRLSDPTSVDADLMLVVAVIGMMANLLGISLLHRGSKENLNVRGASLHMMGDLL
                     SSFGVIVAALLIRFFGWQEADAIIGLAIAVIIIVGAYRLISQSVSILLEAVPKHIELK
                     EVEEAMNSVNGVKMVHDLHVWTLSSGVYALSGHVVVEDQQVSACSPVIHDLERMLEER
                     FHIGHATIQIETEACPANGCTINCREDHHD"
     gene            complement(6184..7737)
                     /gene="purH"
                     /locus_tag="PKM11_03985"
     CDS             complement(6184..7737)
                     /gene="purH"
                     /locus_tag="PKM11_03985"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HNX47698.1"
                     /translation="MVKVERAVISVSDKDGIVDFCKGLSQLGVELISTGGTAKLLSAN
                     GLKVVGISDYTGSPEMMDGRVKTLHPAIFAGLLARRDSPEHMRQLSEAKLKRIDMVVV
                     NLYPFRETVLTKGDDLDEVIENIDIGGPSMIRAAAKNSDSVAVVTDPRHYSALLEEMK
                     ANGGEISKPTLRKLMLEAFRSTAYYDSLIASHLGSEFGDQGFPETYSMGLEKRQDLRY
                     GENPQQTAAFYVDPFAKGVCVSRSEQLHGKELSFNNILDLESALELVREFERPTAIVI
                     KHTNPCGVASADTISEAFTRSYAVDPLAAFGCVIGFNRNVDVATATDISQHFVDCVIA
                     PDYEADALEILKKKKNIRLLRTNAPITLDTAPEWRMKRIKGGLLVQTNKFVPVTAKDL
                     KVVTTRAPTEEEIHGMLFANKVCKHVWSNSIILAKGETVVGIGAGQMSRVDSSMIAAH
                     KAGENAKGSVMASDAFFPFRDGIDTAARAGVTAIIQPGGSIRDQESIDAANEHGMAMV
                     FTGVRLFRH"
     gene            7949..8725
                     /locus_tag="PKM11_03990"
     CDS             7949..8725
                     /locus_tag="PKM11_03990"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HNX47699.1"
                     /translation="MLVISERINGLFAAVGRAIDARDEKFIQQHTVQQMECGAQALDL
                     NVGPGRDDGPAAMDWLVRTVQEVSDLPLCIDTPGIKTMTAGVKACRNKLIINSTTAEM
                     KKMQALFPLAREHDADVICLTMDERGVPNDAESRAEMAMLMMTTAMEYEIMPDRLMLD
                     PLVMPMKAAQDQAMKVIKAMHLFQTLNDPAPRTVVGLSNVSNGGKERSLLNRTFLAML
                     MGAGLDAAIVDVQDAELMAIIKAGELLKSEKLYCDDFLRA"
     gene            complement(8743..9648)
                     /locus_tag="PKM11_03995"
     CDS             complement(8743..9648)
                     /locus_tag="PKM11_03995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47700.1"
                     /translation="MEEWQATTVQRWESERASHPTVAEIGQWERTVADIRVRYKLAED
                     RKERAELCHRLAISYIKMEDYSQAMTWVDLGLAEGSEDRVRDLQEDMALILYLQDRKE
                     EAIAILDELAPKAPIYSQTTAPKRIKPRAPEGAMLNLVCPHCDGEVPYGQLRCPGCGA
                     KVDDKFALVRSTKEGRKVIPREEIETHRTKEFSIFLTDFTVDYDDPANFLTAHRVRFM
                     GGEMVTVTERSWYIWIGSFLLIFFYLVFGALLWSLLSIASPPGPLLFVTVMAAAILLP
                     VTIFFLYVVFPNFLGNAIDFPILRG"
     gene            complement(9701..10822)
                     /locus_tag="PKM11_04000"
     CDS             complement(9701..10822)
                     /locus_tag="PKM11_04000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HNX47701.1"
                     /translation="MSDVAADMKPIDEKWLKEAKKRFASPFMGSNYGHIPVDPMMLSH
                     AAISNGHTIREFYENPEQGAHWVAAAMQSYDLLPITHWYYSLPWLTEIGMEAQYMDWM
                     PPVPKAPLIFDPSQVEELAVPSKEELLKGATLDQLFRSNDYVKKHLPEMFSPIAIATD
                     ITGSGAQLVGVDNFIMWTLLEPELAHVLVRLYMETAAAGAGLIAERYGDAAITTGSVL
                     GNNDIFSDDMVREFSGKYLNEFVTKCFDNGAGPQVFYHFCGNHETDYKVLKEEIVWSP
                     VTVVHVGYKGREVFPSDLLIQEFGGYATCMGTVDTKLMLHGTEEQVYEQAKTQLLKGR
                     SCSSGYILGTACEVPPFTPPENIRALNRAAKDFGTYGTW"
     gene            10907..11446
                     /locus_tag="PKM11_04005"
     CDS             10907..11446
                     /locus_tag="PKM11_04005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47702.1"
                     /translation="MTGDLGSIDVPSLRWEQPKWTQRMHRLVSGETVYATLEWPQAFR
                     STGLSISREGRYSFKRGGFLHPFITVRRQEFEMEHAKMTMDWKGNGELVFTNAQRFTF
                     TRVAMSRFDYEVTDHRGAHMFSLNKKMAAFKHRGEVHISPAGLSHRDIALLVTLGWYL
                     AVMVTEDAAAASGAAAAGG"
     gene            complement(11469..12368)
                     /locus_tag="PKM11_04010"
     CDS             complement(11469..12368)
                     /locus_tag="PKM11_04010"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HNX47703.1"
                     /translation="MSVSQLQGTLDAGKFAVTAEIGPPRSCEVDKLRQMARLLKGSAH
                     AFNLTDNQAANVRMSSIASSVICLQEGLEPVMQMTCRDRNRIAMQSDVIGASALGIRN
                     VLCISGDHQVFGNHPQAKNVYDLDSIQELMVLRNLTKGNNWSGETLPEPPQLYLGAAV
                     NPFADPFEFRVTRLGKKVDAGAQFVQTQCVLDVERFKKFMGLVVEKELHEKVHIIAGV
                     IPLRSHKAALFMKNKVAGMSVPDELVDRLRRSSDPKEEGIRMCVEMMNELSSIKGVHG
                     VHITAIAWEDIIPRLVEEAGIRP"
     gene            complement(12365..13057)
                     /locus_tag="PKM11_04015"
     CDS             complement(12365..13057)
                     /locus_tag="PKM11_04015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HNX47704.1"
                     /translation="MIIAERKPLPEVLGMLDGSNEILVLGCRSCTAICLAGGEKESRA
                     LSEALALHSELKGKGWKVDTLTVERACEKEFLTPLNGFKGTVVSMACGVGAQVVQDHG
                     PEAMVVPGVNTSNMGAPEGMGVFVEKCAGCGDCIIHLTAGICPIARCAKSLLNGPCGG
                     SQNGLCEVSKETPCAWDQIIRSLERSGRLDLLNVNIPPKDWRASRNGGPRRVVNQEAL
                     PGAAQNGWRGEP"
     gene            complement(13054..13431)
                     /locus_tag="PKM11_04020"
     CDS             complement(13054..13431)
                     /locus_tag="PKM11_04020"
                     /inference="COORDINATES: protein motif:HMM:NF014692.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase iron-sulfur subunit"
                     /protein_id="HNX47705.1"
                     /translation="MIVCYCCSRSGMPAALLALEEGGLDDVIVREVPCAGSVEQWEVL
                     RSFRQGAEGVLIVGCLLENCAHHYGSEVAARRSLILERTVQDIGLTKGRVAMVHLAEQ
                     QSARFRRAVEEMRATIREQGGQA"
     gene            complement(13428..14753)
                     /locus_tag="PKM11_04025"
     CDS             complement(13428..14753)
                     /locus_tag="PKM11_04025"
                     /inference="COORDINATES: protein motif:HMM:NF024634.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX47706.1"
                     /translation="MSEPMKAAVFICRAHGANLVAYRGLMKHPRVGHSEILPRCCSTE
                     GRDLIQLHLLGLTTQALLVLGCAASELKRYQDLAALAGIPPTRVAVVPFQVRTAHAAE
                     LALAKVLDEREAKFSAEARSDELLLVGEGISADAAYEQALAEGLKVVRLAPEEVDWNE
                     ARLTGGRGNFVLEAGEVLHQFGHALLSFDPMVIIDRTGLGEGDAVVALAGGEECLRSF
                     VSELEGALSKGGKVYAVVQETPFSGVAEIVYRDLQLRGVVFLRTSEIEVQGASVTVND
                     EHLGRPVKIWTGELVTVRSSRPKAADEVLKVFGMPSSRRSIGIVPGDSGVPGIFLCGS
                     ALSAHHEGDPAGMARAIVCSLVKDIGSPLPRVPIAAIDQERCSKCLTCLRVCPYGAPY
                     FSGEGLSISAERCQGCGLCLSMCPSLAIEMPPSDLRAEAGSVKMGGGLK"
     gene            complement(14746..15921)
                     /locus_tag="PKM11_04030"
     CDS             complement(14746..15921)
                     /locus_tag="PKM11_04030"
                     /inference="COORDINATES: protein motif:HMM:NF019604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HNX47707.1"
                     /translation="MVVLGGGPSGLACAAELAEREVSVVLLEKRETLGGRVQDLSCKG
                     FVHCRQCDVCRVHRLRSQVLSSELISVHTLVELEQVERNNGRYRFDLVRPKEAIDVGR
                     CSRCGKCTEACPTGAMTKVAGRIRLNRNACRSIHGLECERCVSVCPTGSIDLFGEEHL
                     SVNGSAVVVATGSLEFPASKDKRLGYGEVPGVITSMELESFLEGRRDADIGNGKEVAF
                     ILCVGSRSSGMGTEKCSSVCCKYSLRQALALKERFPKLSITMFMMDWRGLSSDDELLR
                     ELATTDVQVVRSRPAEVLAEGGRPSVRYASGNDIICQNFDSVILSVGLVPDLEDDTLS
                     QLAIPRDPWGDLQDDNCSDRGIFLAGSCRGSKDIGHCVADGILVAQQVMKHLEADHE"
     gene            16092..16916
                     /locus_tag="PKM11_04035"
     CDS             16092..16916
                     /locus_tag="PKM11_04035"
                     /inference="COORDINATES: protein motif:HMM:NF013672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HNX47708.1"
                     /translation="MRAVAFTVDVDRDVNLACQGELCSISNGGKLPRFSSSAKGLALM
                     AGLLEEMGIKGTFFWEGRTAEVLSESMDLKGLMKKHEVALHGYDHEDFAGKETGLPLD
                     RQSTRAVLERGTGVLDRVFGKEERGFRAPYQRVTDVLLDELHARTFLYDSSETAELSD
                     GQVRPYRNKNGLPEVPVCWSRDGRGKRIVSYLWPYHEGKRPISDYLDLADGFQEGLLV
                     IATHSWHPVESYCSGLRTSDDVEKGIADLRSLLEHIERSGCELVSIADHLRRKDAL"
     gene            16906..17505
                     /locus_tag="PKM11_04040"
     CDS             16906..17505
                     /locus_tag="PKM11_04040"
                     /inference="COORDINATES: protein motif:HMM:NF024067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HNX47709.1"
                     /translation="MPCNPAYRQAIMLAWDSIAGIPDKELASASKADLRGRELVLQTV
                     GQETVVDLADRCLTAPDVLGGGWGLATLHHLKGCLTWKRDEEWTSFDVIPTGRPFAEA
                     FRQRALMPLAERYGRSPDALLKDGAALGGTKFDLGDAAIMIQAFPRLKIAIAAWQGDD
                     EVPGKAVMLFEAGGARTLPAEDLAEVGISIAQAILSTGR"
     gene            complement(17489..19162)
                     /locus_tag="PKM11_04045"
     CDS             complement(17489..19162)
                     /locus_tag="PKM11_04045"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HNX47710.1"
                     /translation="MKSNIEISQEAKVLPIDQIAVQLGIAEEELVPYGRYIAKVPLSV
                     LKRYDDRPNGKLILVTAITPTPAGEGKTVTTIGLVEALGKQGHKVMGAIREPSLGPTF
                     GLKGGATGGGLAQVYPMWDIDLHFTGDIHAVGAAHNLLSAILENHIAMGNQLNIDPTR
                     IFLKKAIDMNCRELRNIVVGLGGRKEGGIPHESGFIITVASEISAILALTSGMTDLKE
                     RLGRILVGYTYDNQPVRARDLGCVGAMATLLKDAIHPNLVQTLEGQPFFIHGFPFANI
                     AHGNSSIIATKYALKLADMVVTEAGFGADLGAEKFFDIVCRNDGFRPNCAVLVCSIKA
                     LKMHGGCPLKSVGCEDLDALQKGFSNLDKHIENLRHFGVPIVVAINHFPADTEEEVRT
                     IREHCRAMGVRCALSEVFEKGGAGGQELADQVTEAIEKDESDFRFLYDTELPIKEKIR
                     IIATEMYGAQVVEYETAAQRHLRVIEESGQGNFMVCMAKTQLSLTDKPQMKGAPTGWE
                     LTIREIFVSAGAGFVVPICGRIMLIPGLPSQPSALGVDIDEDGKITGLY"
     gene            19261..20160
                     /locus_tag="PKM11_04050"
     CDS             19261..20160
                     /locus_tag="PKM11_04050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetrahydrofolate dehydrogenase/cyclohydrolase
                     catalytic domain-containing protein"
                     /protein_id="HNX47711.1"
                     /translation="MGARLLEGKEVADRIRKDLAVRIAALKEKGVVPGLAVVIIGDDP
                     ASVSYVTMKGKACQDLGMYSLTVRKPADLSEDALLQQIDYLNRDPKVHGILVQLPVPR
                     HIDVGKVIAAIDPKKDVDGFHPTNVGKMLIGEEDGFLPATPYGIRVMLSSYGVDVTGK
                     HVVVVGRSNIVGKPMAAILMQKGVDATVTVCHSRTRDLKAITAQADVLISGIGKALFI
                     TADMVKEGAVVVDAGSNRIDDPSAPKGYRFVGDVDFDNVKEKVSAITPVPKGVGPMTI
                     VMLMSNTVLAAERSLERQNRPKV"
     gene            20190..20837
                     /locus_tag="PKM11_04055"
     CDS             20190..20837
                     /locus_tag="PKM11_04055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HNX47712.1"
                     /translation="MLRECGEHGYFRGETCPICGEPGKFLLSEQELDQLGRTLAGVLR
                     HFPERFGLDMDEQGFVSIRGFINALRDSNRRYHWLRPHHIVAIIETDPKGRYQISNDL
                     MRATYGHSLELDLKLPTENIPDHLYYPATPEEADIILETGLRPSDRKMVHLSRTYQDA
                     LNAGKVRVEAPIILEIDSAAAIAAGNVISQAGKTVFLAQEIPPEFLSRKEEEEVL"
     gene            complement(20927..21196)
                     /locus_tag="PKM11_04060"
     CDS             complement(20927..21196)
                     /locus_tag="PKM11_04060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47713.1"
                     /translation="MSLILVSAATTAAATSAVSITTAVSVGVGGALIAILLIMLLSSR
                     ELISASNKGSKKVLATLDSAIVPLLVVFSLTIVFQVLQIVGTISV"
     gene            21334..22242
                     /locus_tag="PKM11_04065"
     CDS             21334..22242
                     /locus_tag="PKM11_04065"
                     /inference="COORDINATES: protein motif:HMM:NF022430.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2797 domain-containing protein"
                     /protein_id="HNX47714.1"
                     /translation="MFETADEILRRKGMVAYDRHAISWEWEGYQPILVTYDQKAKEVQ
                     ELTDQFRPGERFDLLISDARRCVGSFIDGEYEPCKMRNVVSGQFDQCPLCASTWIPVQ
                     NCVFEPECDGTNITNERCIGKGGDICAKPTHVYAAFYGDLVKVGMTLSTRFMERAIEQ
                     GADAIARLGTYPNRRAARDAENVLSKALHATQWVRKTTFLKAQGSIRDREVYQARLDA
                     LFSSLDGVATDPGELNMLDRYPLLPYEPSKAVFAEVTGRHRGEVLGCKGKWLFYRLKD
                     GRTMLLNMSSVPSRYITISLANINKP"
     gene            22285..23238
                     /locus_tag="PKM11_04070"
     CDS             22285..23238
                     /locus_tag="PKM11_04070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1743 domain-containing protein"
                     /protein_id="HNX47715.1"
                     /translation="MVQVLKPEEVTEKYGRLFCRGVFTLVDERNGVAQVIEECSAKGP
                     VEWDACNRKRAGGAITNITVEGNTIIMDTIIGEGELHFGPASKDLGGQGLRSLVVDGD
                     KVRTTWVGLAGASVGIGACMPQGPGTIATEYPDDVKIGGAHKVEVTVITPKLVRVIIS
                     VDDTDTKEKGASWSMMLKAARECPVGTFLQHKIIQLNPNVPQKTTNCSSSGVSFAIKE
                     SEIPALLDYFKEAFRKNTYSQETTMAYYVGLRIPKDLEEYGWNAKKVIYKPQDALDVA
                     ERTGVQVVEITGRRGTIGAVAAIGCFDLGLKAAGLPEDFEN"
     gene            23267..24049
                     /gene="uppS"
                     /locus_tag="PKM11_04075"
     CDS             23267..24049
                     /gene="uppS"
                     /locus_tag="PKM11_04075"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="HNX47716.1"
                     /translation="MSNEITRVFANTAYQTYEKRLFKEVMEGDIPEHVAIIMDGNRRF
                     AEEIGLAVHEGHIKGKDKLEEVMEWCQEMGIKVLTVYAFSTENLNRDENEVHYLMQLF
                     EESFLKLAEDQRIHKNRIKVTVLGQRELLPEKVIKAIEVAENRTKDYDDYFYNIALAY
                     GSRQEMITAIKRIASKVKDGELSVDDIDEETFSSFLYTADFKDPDLVLRTSGEERVSN
                     FLLWQLAYSELYFTDVFWPGFRKVDFLRAIRTYQDRQRRFGK"
     gene            24092..25816
                     /locus_tag="PKM11_04080"
     CDS             24092..25816
                     /locus_tag="PKM11_04080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04190 family B12-binding domain/radical SAM
                     domain protein"
                     /protein_id="HNX47717.1"
                     /translation="MSLVMSKEDIIFLHAPSVYDFRKEFLFYGPVSDMVPSTPVFEMY
                     PFGFTSMASHLARNGYKVRLVNLASMMLNDRKLDVEKLISKLKAKVFGIDLHWLPHAH
                     GALEIAKLVKKHHPDAKVLFGGFSSTYFQEELLRYPQVDLIMKGDSTEEPLRQLMEAL
                     KNGTPLENVPNLSWKDEKGEHHNPITYVPDSLDYQDVDYGWIVRSVIRHLDLEGHKPF
                     KDWDRYPITMVFSIKGCHLNCTVCGGSCPAMHKFLNRQKPAFRSPEKLAQDVYNIQQY
                     IKAPTFIVGDPRRGGLDYMQRFFAEVKRLGVTNSLVFEFFTPPDEEFYKLASTHTKGF
                     AVEISPDSHDPEVREALGRKYSNEELETSIKNALKYGAERFDVFFMIGLPKQTRESAV
                     KSAEYAKTLYLAADKDPRLCVFISPLAPFLDPASLAFEDPERFGYVSLARTLEEHRAR
                     LTSPSWKHVLSYETKWMTRDDIAEVSYEAADAINRARFECGLIDKEELDYRLKRSAEA
                     ADMMKRVDAAMVITDPEEKRKAFQELQRRSEELMESTITHKREMEWSAKGLLWSVPRA
                     AWAVLRGV"
     gene            complement(25813..26901)
                     /locus_tag="PKM11_04085"
     CDS             complement(25813..26901)
                     /locus_tag="PKM11_04085"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HNX47718.1"
                     /translation="MVKELNYDIVVVGAGPAGSTTARFAAEAGASVLVLERRAQIGVP
                     VRCGELMPDLEEMRNIFPLAGDMSDIFEVPSDLVSLKFSSIRIFSPKNTKYEVPFTGY
                     TTDRDRLDQFYASQASKAGAEIMTGQRVLKVEQGMVRTDDLSVRAKVIVGADGPLSMV
                     GKAFGLERSADLCPAVTVQVPGEFEPVPEMYFGTVAPGGYAWVIPKKGCANVGLGVSK
                     KFARMTVNEYFEGFVKFRGLTAGKPEGKVVPMSKPVKRTVSGQAMIVGDAAGQVMAVN
                     GGGIPMARITGKVAGTIAAANVLQGTPLTDYETEWRKQVYKPLRTAARTKVMAELCFG
                     SVWRTETAMKVLGPRRMNNLIRCRPMFP"
     gene            complement(26923..27885)
                     /locus_tag="PKM11_04090"
     CDS             complement(26923..27885)
                     /locus_tag="PKM11_04090"
                     /inference="COORDINATES: protein motif:HMM:NF012568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HNX47719.1"
                     /translation="MSQSWDSSIKDELQMVEQEIRRSISSEQPVLTEICDYVISSGGK
                     RMRPGVTILSYLASGGKEVSEAVKIAAAFEMIHSATLIHDDINDRSEKRRGRLSAYKK
                     FGLQQALVSGDFLFVKAFAIGGFFNEEIVSLVAEACTAIAESEIVQFEKEGEVASLDV
                     YLGIIEGKTAKPIMAGARIGAYLAKAEPDRIHALGEYGLNIGMAFQIVDDILDIMGTE
                     KSLGKPRMVDFFEGKATLPLIHAMEDPAVGPRLYQLFHKKAKDEQDIQEASALISRTN
                     AVERSKQKAKEYAEKALRSLEVLPDSEHKVGLQRLAAKVVDRDY"
     gene            complement(27998..29452)
                     /locus_tag="PKM11_04095"
     CDS             complement(27998..29452)
                     /locus_tag="PKM11_04095"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit N"
                     /protein_id="HNX47720.1"
                     /translation="MDYTALYPEIIVALFALALPAVNLLIKDNRFLAAVSLAGVGLSM
                     LAVLMFYLDGTGSIAFDNGLLVLDNFSALFMMVFLSVAFVVILASVKYIEKEKHGAEY
                     YSLVLLATVGMMLVASATDLFVLYIGIEITSLSSYALVAFRKKDIKGTEAATKYFIFG
                     GISSAFTLFGISLIYGVTGTTSFAEIGALVGTLTEYKEMLWLALVMVIVGFGFKVAMV
                     PFHSWAPDVYEGAPTTITALLAAGSKKMGFVAMFKFFLIAMLAIKADWEIVVAVLAIV
                     TMTVGNLAALQQTSIKRMLAYSSIAQAGYILIAVAVGTEYAVTGGIFHILTHAFMKGG
                     AFIVVATLATVAIGEKIADYKGLAKRSNFMAFSMTVLLFSLAGIPPLAGFASKVVLFS
                     SPIMGTVDGADWMIWLAVAGIINSAISLYYYARVVKYMYVDELEEGAPSEKLKLPKSM
                     MAAVAICVVAIIGIGVFPEPFIQLCKDAAQALFA"
     gene            complement(29453..30940)
                     /locus_tag="PKM11_04100"
     CDS             complement(29453..30940)
                     /locus_tag="PKM11_04100"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HNX47721.1"
                     /translation="MEIPILSLMLLVSLVGAVVTFALGKNPKMAKISALVFSAIPMLL
                     SLFMLTQYVQTAGGYQFRESFTWIDSLGISYILGVDGISVPMVFLSTLLVFLAVIFSW
                     DVDHRTNQFMALLLVLELGVLGVFMALDYFLFYIFWEVVLIPMYFLISVWGGPRRSYS
                     AIKFFIYTHIASLAMLLGIFALYFEAASFNGFYSFGMEDINSVSPLFGLTFQIVVFGA
                     LFFGFAVKMPTFPFHTWLPDAHVEAPTAGSVLLAGLLLKMGAYGIIRVALPALPDGAG
                     EWQIVMVILAILSIVYGAIMCIAQKDLKKMVAYSSISHMGLVLLGFATFTEIGIAAGV
                     FQMFAHGLITAVLFMMCGVIQHKAGTRNIPRLGGLAAKMPIAAVFMMIGFMASLGLPG
                     MVGFVAEFSIMTATFDAFGWLLLIPVTSIAFTAAYYIWAMQRTLFGPLTKEVDTEHLH
                     DVYWFEALPLAVLCGLIVLFGMFPAMVMDYIRPALGTVLGLLGGI"
     gene            complement(30945..32909)
                     /gene="nuoL"
                     /locus_tag="PKM11_04105"
     CDS             complement(30945..32909)
                     /gene="nuoL"
                     /locus_tag="PKM11_04105"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: protein motif:HMM:NF005141.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HNX47722.1"
                     /translation="MDILEYAWLIPVLPLLAFVFIAFLGKKLGDLNGYIAVGGVGAGM
                     VLALWTAYELLTTGRIYSTSQTWVVLSNEYTLEMGVYLDNVAAMMLIVVSFIAFLVVV
                     YSTAYIHDQGPRRHRYFTEICLFVGVMLGLVLANNFFQMFVFWELVGVCSYLLIGFWY
                     ERPAAARAAKKAFLVTRVGDVMFMIGLFILFTELRTFNYVDVWAALDTADPTMMAFAA
                     FFLFGGAIGKSAQFPLHDWLPDAMEGPTTVSALIHAATMVNAGVYLVARSFPIIATSA
                     EVALFVGAIGGITAFIAATMALCAPKIKGVLAYSTVSQLGYMILGLGAGAFLWHHGHH
                     AAGSIAFGAGLFHLMNHAFFKGQLFLGAGAVIHYVHTEDLAKMGGLGKYMKVTMITML
                     ISCISIAGIPPLSGFWSKDEVLAMTFEAGDAGLTFMVLWVLGVLTAFMTAFYMFRMWF
                     MVFGGKPNEGTVHATEHGHHKHEAPIAMLIPLVILASLAFASGFSLFIGDGFFGAIYY
                     GDAHVLTIGEKLEEVFTSPLTYISIVAAVAGILLAYFSFYKSKISAEKVVSKGFPKAM
                     HQLLLDRYKFPQAYDKIGYVGVYGFSLLLDKFDRYVIDGIVNGIAAFLMAMGGVTRKL
                     QNGFVQSYATLLVIGVSVIVILLYVVGVLR"
     gene            complement(32912..33214)
                     /gene="nuoK"
                     /locus_tag="PKM11_04110"
     CDS             complement(32912..33214)
                     /gene="nuoK"
                     /locus_tag="PKM11_04110"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HNX47723.1"
                     /translation="MIPLEFVLIITSVLFVIGAAGVLLKKNAIQILMCIEIMLNAAII
                     NLVAFSTYFGDGTGQGFALFAIGIAAAEVTIALAILLNLNKLRKTVDVDDINLLRW"
     gene            complement(33211..33459)
                     /locus_tag="PKM11_04115"
     CDS             complement(33211..33459)
                     /locus_tag="PKM11_04115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47724.1"
                     /translation="MKRGDSTQAIVAKVLVVGLLLELMLYSVFTIEWGDIGNTVIKTA
                     EVGTVIFTDYGAAVLMLGLMLFAVIIGGVFIAQEDDDE"
     gene            complement(33456..33767)
                     /locus_tag="PKM11_04120"
     CDS             complement(33456..33767)
                     /locus_tag="PKM11_04120"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: protein motif:HMM:NF012709.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HNX47725.1"
                     /translation="MILDGTTLFFLIFGALTVGCAAMVVISKDIVRSVVWLAATFVGV
                     AVLYIFLNAEYLFLIQLLVYVGAINVLILFGIMLTKRRMVGGDACEEYEQDIVKRRRS
                     K"
     gene            complement(33767..>34405)
                     /locus_tag="PKM11_04125"
     CDS             complement(33767..>34405)
                     /locus_tag="PKM11_04125"
                     /inference="COORDINATES: protein motif:HMM:NF024634.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX47726.1"
                     /translation="CTILYPWEKLIYPDNYRGRPGIVLDKCIGCARCAKECPNQCIEM
                     VDYQDAEKGKVKRPQVNVGRCMMCGNCAEMCPTNAMIVTPEFELCSYSRAGLIFDPVK
                     LQHAHKPGYEVNFEFALLSEMKAGGEVKTYAKNDPNIHDTVSLDGSKCISCSRCAKTC
                     PTGAIEMADTGELNPKTKKPIKHPKFDNAKCVVCEQCVEVCPKSCLSIKEVL"
BASE COUNT         7106 a        10382 c        10203 g         6714 t
ORIGIN      
        1 gttcgtcacc tttcaccgga attccagagg aggaggcgtc gcgaacgacc tcgtcatcgt
       61 gcaacaggaa gaactcaagc ccggtgcctt tggccagctg ctcggcctta ttttcctttc
      121 ccgaccggac gccgttgatc agcaggacct ttctcctgac ctggaggtcc agctcgtcgg
      181 ccagttccga cagtcgcacg gcggtcgcca cgcccacggc cgtgggatcc gacaccagga
      241 ccagaaggtc catctccttg gccgtgcggc gggagaggtg ctccatcccc gcctcgttgt
      301 cgattattac gtgggaatag gattccatca gctgatcgac gaaaacgcgt agaaggttgt
      361 tcacgtagca atagcagccc ggcccctcgg ggcggcccat ggtcaaaagg tcgtaaccgt
      421 gaccttcggc cagtatctcc cgcagcttga gcttcaggta ctcctgcttg ctcatgtctc
      481 ggggcggttg accgcctttg ctcaggagcc cttcccggac ctggcctacc gttcccggca
      541 cgtccgtccc cagcttctgc cccaggttgc tgttgggatc ggcgtccacg gccagtacta
      601 catctctttc cgacagtatc cggaccagca gggcggacac ggtgctcttc ccgaccccac
      661 ctttgcccgc cacggccgcc acgaagctca tgacatgcca cccagccggt agcgctgcct
      721 tatcgcctcg accgttccgt tgagcagttc gagcaccctc tccgccttcg cctcgtccag
      781 gccgcccagg ccgcactgcg gggttatcag ggaacgctcc aggaccaggt ccaaatccat
      841 gcccttgcga tagagcaggt ccatgtagct ctcgaacctc tgcagcaacg tcccgacggt
      901 ctccttagcg atctggtcct ccatgttcgg aatgagcccc caggctatgg agccgccccg
      961 gtccaggaag gccgagacct ccttcgggaa cagcgaaacg gtgtgggcgt agttgtaagc
     1021 gtcaaagctc agcatgtcga tggacgtgga aagtagcaac ggccaatcgg tgttcccgca
     1081 gcagtgcatg gccttgatgg cgtcaacccc ctccagcacc tcgtcggtcc agtccaccac
     1141 ctgacgttgg gatatggagg cgaagggcgt tccgatgagc gtgagcgagg gctcgtccag
     1201 gaatatgatc ggccggtcgg atatctccct gagcttcctg gcctgccact tggcctgcat
     1261 gttcaagttt cgtcgtatga tctcgccgta cgcctcatcg tagatggcgg ccttgccgtt
     1321 ctgatcgagt atctgcagcc cggcgctcac cggaccggtc acctggcctt tgaccgccgg
     1381 cagcttcttt cccttgaacc ggtcaaggag agcgtacagc ccctggaagt ggtccttgtg
     1441 atgggcgaaa tgttcgatgt cgtccgtgac caccgcggtg tagaacgcct cgggatcgta
     1501 atcgttcaga tcgacgatta ttcttttctt gtgcgcgtcg accttcacgc ctggaagagt
     1561 gaacgagaac tgcgcgtaca tgttctcccc gaaaccgaga gagggcatct gcggccagta
     1621 ggggacctcg ctcatgcttg ccgtgacgat gtccagagcc ttctgggggt ccttgtgcgg
     1681 cagggagcct atcccggtcg cggcgcagtt ccaggccatg gcctggagtt atcgttctcg
     1741 ttataaaatc atttggtggc ccggatggct atgtagtact ggtcgatgaa gagcttgccg
     1801 tccgcctcct cgacggccat acgccccttc agatcggatg acaaagagga caccacacgt
     1861 tcgatctcct tagcgtcaga aggctcggcg ttccaggtca tggtggacag cgcaagatga
     1921 cggcggtact cgcgcacctc gatgtcccga agaccggtct cccccagcat cctctcccat
     1981 tccctccgtc catactcccg aacgtgagag cggtcgtgga ggaggtccag atggttcatg
     2041 gttcggtcga cctcaggatc gtccggaacg ctgcggtcgt ctatgaccat gaccccgtcg
     2101 tccttgagca ccctggccat ctccttcaac gctttgttga tatcagggaa gtgatgcggt
     2161 gcccggcggc aggtgaccgc atggaacgag ccgtcgggga agggcaggga gcggacgtcg
     2221 cccctcagcc atgcgatgtt cgaaatcgat cgcttgaccg cctcttccct ggcgacctcc
     2281 aacatacggc gggtgaggtc caggccgatc accgttccgg cagccggtgc cagatgcatg
     2341 gccacatgtc ccgtccccgt ggccacgtcc agagcgagct tgtcatgaag gtccccgcac
     2401 atctcaccaa cgcgctcgag aacttcctta tcggcgtgag aggcgctttt cacatagccc
     2461 tcggccctct taccgaatat ctcctggacc tttttcccgt tcacgtaact gcatcctaat
     2521 gaaaatattt caacgctgtc aggaaaagat tatccccttt tcgctaaata tcaatcacat
     2581 gcggctgatc acggtcaacc ggaccaagcc caacgcctcg atcgagttct atggatgccc
     2641 catgcagtgc aagtactgct cccatacggc ggcgcagtac aaggactacg acctggacaa
     2701 gataatactg gccatgtccg ataacgggat aaggagcgtc ttcatcggag gggcggaacc
     2761 ggccgtgcac agcagggaag ccttggaact gatccgaata cttaaggcca agggcaagga
     2821 ggtcatcctt aagaccaccg ggcacgatcc agatttcgta gccgccgcca aggacaaggt
     2881 cacccgcttc gtcctggagc tgaaggcgcc cctcgacgag cctgagctgc tgacgaagct
     2941 caccatatac gatatggaga aggcgaagga gcaacaggag aagttgcggc ggacgctgga
     3001 gataatgaaa ggttcgaggg tgcgggccac attgcgcgtc attcccgagc gatacacaga
     3061 ggatacggtg gaaagaatgg ccaaggacct caagggctac gtggatgagc tgcacctcat
     3121 ccagttcatg tccagccaga acgacgtggg ctatgccggc atatacaacc cgggaccgga
     3181 ccaggagacc atgatgaggc tcggacgaat agcgcgcaag catcttcccc gggtcaaggt
     3241 agtaggcaac ggcttcgacg tcatcctctg atttgctcga tcgacggaaa tctgctcagg
     3301 tcggtgtgcg gcaggaagga cgcggacgag aaacggtcga agaagcgttg atctgtcgat
     3361 agctccacgt aggtcatcgc ccgatgcgcc gccagcgcct cctctcgttt ttcctgagag
     3421 agaaggcaaa gcttggcccc gtccagtgag gcgttcccta ggaaggtgaa gcgttcccgg
     3481 ggcaggtccg gcaatagacc tatcgccacc gcgttatcga ggtcgatgtg atgaccgaac
     3541 ccgccggcga tgtacacccg ctccaggtcg gtgaaatcaa taccggcggt gtccagcagc
     3601 acctccgccg ctgcatatag ggacgccttg gtgcgcacga tgttggcgat gtcctcctcg
     3661 gtgaccgtga tatctctgcg tctctccacc ttgtccgtgg ggcagcagct catgccggtg
     3721 gccttgacgt cgtagccgtc cctctccacg tccttggaat agaccagaac gtactccttt
     3781 ccgaactcgc catccctgac gcgttccgag ggctgcaggt ggcccttctt gtccaataca
     3841 cccgtaagga acaactgcgc cagcagatct atcagcccgg agccgcaaat ccctttggga
     3901 cggacctttc cgatggtgct gtactccacg ccgcccttca gggagacctt ttcgatcgcc
     3961 ccatcgccgg cgcgcatgcc gtggcagacc tcgccgccct cgaacgccgg accggcggag
     4021 gcggaacagg ctaaaagcca atcattgttg ccgaggacta tctccccgtt cgttcccacg
     4081 tcgatgagca ggctgatacc ttcgttcctg gccattccgc tggccaccac gtccgctacg
     4141 acgtcgccgc cgacgtagct cgcgcgtccg ggcaccaggt gcaccgaggc ccgggggttg
     4201 acgttcagac caagctcgct ggcgttgatc cgcggtgata ggttcgtgac cggcgtgtaa
     4261 ggcgcgtaac gtatgcactt ggggtccagg ccgagcagca tgtgcatcat ggtggtattg
     4321 ccggccacgc taacggccat gatctcctcg gcgcagacct tcttgccctt gccgacgcag
     4381 acatccccgg tattgcacac ccgggccagc atgtggttga tggtgtcaac tatcgtgtgc
     4441 cggaggcgct cgagcccgtg gtcctcgcta tacatgatcc gcgccagcac atcctcgccg
     4501 tacatcagct ggcggttgta atcggagacc tgcgagatca tctccccggt gctgagatcg
     4561 accagttgca gggcgaccgt agtggtgccg atgtccactg acaccccgaa gttccgggag
     4621 acgacgttcc aaggcaggac gtccaccagt atgttgccgt ccaggaacgc ggtcaccgtc
     4681 cattcccctt cccttatggc cctgggcagt tcccggagca gggagagagg cacctccagc
     4741 gcgccaggct cgtaacccag ttgtttcaac aggcgctcta ggtcggcgtc gttgtcctgc
     4801 aaggtcggag gacgcagttt ggcgtagatc gccctcacca ggggggagat ctgcttcaga
     4861 tcggtgctca cctttccacc gactatctgc ataggcttga gctgactttc ttcggggacg
     4921 aagacgatac aatccccttt gaccttggac aggcatgcca ggcggtagcc gttcgaccta
     4981 tcctcctcgg ttatgcgagg ggtgttctga gagtccacgt ccccctcgac caccacccgg
     5041 cagcgtccgc agacaccttt tccggcgcag gcgctgttga tctccactcc ggctaggatt
     5101 gccgcctcca gaaggttggt atccactgga gcttcgatgc tgcggccttt gggatggaag
     5161 gtcacctggg ggctcatccc gagcgaatcc cttcctgcgt taataaaagc tctcgcaagc
     5221 caccctgaaa atgatttagg gcaagactgc ggtcaggatg agcatggagc atgggcacga
     5281 ccaccgcgga ggttcgacca agatgctgac gtacgccttg gtcatcaccg ccgccttcgc
     5341 cctggtggag ttggtcggtg gcttgctcag cggtagcctg gcattgctca gtgacgccgg
     5401 tcacatgttc actgacgtgc tggcgctggg cctcagccta ggagcttcac tggtggccgc
     5461 ccgtcaggcc acggaacgtc atacatacgg attcctgagg gcggagatac ttgtcgcgct
     5521 ggtgaacggg atcgccctgg tcgggatatc gttgctggtg atacacgaag ccctgggccg
     5581 gctctccgat cccacatcgg tggacgccga cctcatgctc gtcgtggccg tcatcggaat
     5641 gatggcgaac ctgctgggaa tatcgcttct gcatcggggc tccaaggaga acctgaacgt
     5701 gcgtggcgct tccctgcaca tgatgggcga cctgctttct tcgttcgggg tcattgtcgc
     5761 ggcgttgctg attcggttct tcggctggca ggaagcggac gccatcatcg gactggccat
     5821 tgcggtcatc ataattgtcg gcgcgtaccg cctcatctcg caatcggtgt cgatattgct
     5881 ggaggcggtc cccaagcaca tcgagctcaa ggaggttgag gaagccatga actccgtcaa
     5941 cggtgtgaaa atggtgcacg atctacacgt ctggacgctt tcgtcgggtg tttatgccct
     6001 tagcggccac gttgtcgtcg aggatcagca ggtcagtgcc tgttcaccgg tcatccatga
     6061 tctggaaagg atgctggagg agcgtttcca tatcggtcac gccaccatcc agatagagac
     6121 ggaggcttgc cctgccaacg gctgcaccat caactgccga gaagaccatc acgattgatc
     6181 cggtcagtgc ctgaagagcc tcactccggt gaacaccatg gccattccgt gctcgttggc
     6241 cgcgtcgatg gactcctgat cgcgtatgga accgcctggc tgtattatcg ccgtaacccc
     6301 ggccctggcg gcggtgtcta tgccgtcccg gaaggggaag aaggcgtctg atgccatcac
     6361 acttcccttg gcgttctccc cggccttgtg cgcggcgatc atcgaggagt cgacgcggga
     6421 catctgcccg gcgccgatgc cgaccacggt ctcacccttg gccaggatga tgctgtttga
     6481 ccacacatgc ttgcacacct tgttggcgaa gagcataccg tgaatctcct cctcggtcgg
     6541 ggcgcgggta gtaacgacct tgaggtcctt ggcggtgacg ggcacgaact tgttggtctg
     6601 caccagcagt ccgcccttga tgcgcttcat acgccactcg ggagcggtgt ccagagtgat
     6661 tggggcgttc gtcctgagaa gccggatgtt cttctttttc ttcaatatct ccaaggcgtc
     6721 ggcctcgtaa tcgggagcta tgacacagtc cacgaagtgc tgggagatgt ccgtggccgt
     6781 agcgacatcg acgttgcgat tgaagccgat gacgcaaccg aacgccgcta gcgggtcaac
     6841 ggcataggag cgggtgaaag cctccgatat ggtgtcggcg gacgccaccc cgcagggatt
     6901 ggtgtgcttg atgactatgg ccgtgggcct ctcgaactcc cggaccagtt ccaacgcgga
     6961 ctcgaggtcc aggatgttat tgaatgaaag ttccttcccg tgcagttgtt cggagcgaga
     7021 gacgcacacg cctttggcga aagggtcgac atagaacgcg gcggtctgtt gcgggttctc
     7081 gccatacctg aggtcctggc gcttctccag ccccatgctg taggtttccg ggaaaccctg
     7141 gtccccgaac tccgagccca ggtgggaggc gatgagcgag tcgtaatagg cggtggagcg
     7201 gaacgcttcc agcatgagct tgcgcaaggt cggtttcgat atctcgccgc cgttggcctt
     7261 catttcttcc agtaaggcgg aatagtggcg cgggtcggtg acgaccgcca cggagtcgga
     7321 gttcttggcc gccgccctga tcatggacgg gccgccgatg tctatgttct cgatgacctc
     7381 gtccaggtcg tcgcccttgg ttagaacggt ctcccggaac gggtacaggt tcacgaccac
     7441 catgtcgatg cgcttcagtt tcgcttcgct caactggcgc atgtgctccg gggaatccct
     7501 tctggccagt aacccagcga agatggccgg gtgcagcgtc ttcacgcgac cgtccatcat
     7561 ctccggggaa ccggtgtagt cggatatccc cacgaccttc agaccgttag cggacagcag
     7621 cttggccgtg ccgccagtgg agatcagctc cacgcccagc tggcttagcc ccttgcaaaa
     7681 atctactata ccgtccttgt ccgagacgct gatgaccgcc ctttcgacct tgaccatgag
     7741 aattccttca gtgggatggg cacaccacga aagatggtat gccaggggta tattgctcaa
     7801 tccgtattaa agatagcgat agccgatagg aatcaccgga cgactggcca tatcgcttag
     7861 ttcgttcatc ataaattatc atcggaggga cggtcgggaa gggcgggaac gcttaaaacc
     7921 gtccgtagcc atagcctttc gaaccgagat gttggtcatc agcgagagga taaacggact
     7981 gttcgccgcg gtcggacggg ccatagacgc cagggacgag aagttcatcc agcagcacac
     8041 cgtccagcag atggaatgcg gagcgcaagc cttggacctc aacgtcggcc cgggaaggga
     8101 cgacggcccg gcggccatgg attggctggt gcgaaccgtt caagaggtct ccgacctccc
     8161 gctgtgcatc gataccccgg gcatcaagac catgaccgcc ggtgtgaagg cctgccgcaa
     8221 caagctgatc atcaactcca cgacagcgga aatgaagaag atgcaggcac tttttccttt
     8281 ggccagggag cacgacgcgg acgtgatatg cctgaccatg gacgagcgtg gcgtgccgaa
     8341 cgacgccgag tcgagggcgg agatggccat gctgatgatg accacggcca tggagtacga
     8401 gatcatgccc gaccggctga tgctggaccc cttggtcatg cccatgaagg ccgcccagga
     8461 ccaggccatg aaggtcatca aggccatgca tctcttccag acgttgaacg atcccgcacc
     8521 gcgaacggtg gtcggacttt ctaacgtctc caacggaggg aaggagagaa gcctgctgaa
     8581 ccggacgttc ctggctatgc taatgggcgc cggtcttgac gcggcgatcg tggacgtgca
     8641 ggacgccgaa cttatggcca tcatcaaggc tggcgagctt ctgaagtcag agaagctcta
     8701 ctgcgacgat tttctcaggg cctgagggaa cctggctcag ccctagcccc ggagtattgg
     8761 aaagtctatc gcgttcccca ggaagttggg gaagacgacg taaaggaaga atatcgtgac
     8821 gggcaggagg atcgccgccg ccatgaccgt cacgaagagg agtgggcctg gagggctggc
     8881 gatgctgagc agagaccaca gcagggcgcc gaacaccaga tagaagaaga tcagaaggaa
     8941 tgacccgatc cagatgtacc atgacctttc ggtgaccgtg accatctccc cgcccatgaa
     9001 cctcacccgg tgcgcggtca ggaaattcgc cgggtcatcg tagtcgacgg tgaaatcggt
     9061 caggaatatt gagaactcct ttgtgcggtg cgtttctatc tcttctcttg gtatgacctt
     9121 tcggccttcc ttcgtcgacc ggaccagggc gaacttgtca tccaccttcg ccccgcagcc
     9181 tgggcacctc aactgcccgt aggggacctc accgtcgcaa tgagggcata ctaggttgag
     9241 catcgctcct tccggcgctc tcggcttgat gcgcttggga gcggtggtct gggagtaaat
     9301 aggggccttg ggagccaact cgtccagtat cgctatggcc tcttcctttc tgtcctgaag
     9361 gtacagaatg agcgccatgt cctcctggag atcacggacc cgatcctcgg agccctcggc
     9421 cagaccgaga tcgacccagg tcatggcctg ggagtaatcc tccatcttga tgtaggatat
     9481 ggcgagacgg tggcagagct cggcacgctc cttgcggtcc tcggccagtt tgtaacgtac
     9541 acggatatcg gccacggttc gctcccattg tccgatctcg gcgacggtcg gatgcgaagc
     9601 gcgttccgac tcccaccgtt ggaccgtggt agcctgccat tcctccattc gcttccccga
     9661 acagtattca gttgaatgga taattaaact atctagcgca ttaccaggtc ccgtaagtgc
     9721 cgaagtcctt ggccgctcgg ttgagcgccc ggatgttctc cggcggggtg aacggaggca
     9781 cttcgcaagc ggttcccagt atgtaaccgg aggaacaact gcggcccttg agcagttgcg
     9841 tcttggcctg ctcgtacacc tgctcctccg ttccgtgcaa catcagcttg gtgtccacgg
     9901 tgcccatgca ggtagcgtaa ccgccgaact cctggatcaa caggtcggag gggaacacct
     9961 ctcggccctt gtatccgacg tgaacgaccg tcactgggga ccacacgatc tcttccttca
    10021 gcaccttgta gtcagtctca tggttcccgc agaagtggta gaacacctgc ggcccggcgc
    10081 cgttgtcgaa gcacttggtc acgaactcgt tcaggtactt cccggagaac tcccggacca
    10141 tgtcgtcgga gaagatgtcg ttgttgccga gcacggaacc agtggtgatg gccgcgtcgc
    10201 cgtaacgctc ggcgatgagc cccgctccgg ccgccgccgt ctccatgtac aggcggacca
    10261 ggacgtgggc gagctccggt tccagcagcg tccacattat gaaattgtca actcccacca
    10321 gttgcgcccc gctgcccgtg atatcggtag cgatggcgat gggcgagaac atctccggaa
    10381 ggtgcttctt gacatagtcg ttggaacgga acagctggtc aagcgtggcg cccttcaaaa
    10441 gctcctcctt gctgggaacg gcaagttcct ccacctgcga tggatcgaat atcaacggcg
    10501 ccttaggcac cgggggcatc cagtccatgt actgcgcctc catgccaatt tccgtcaacc
    10561 agggcaagga gtagtaccag tgggttatcg gcaaaaggtc ataggactgc atggcggcgg
    10621 ccacccaatg cgccccttgc tcggggttct cgtagaactc ccgaatggtg tggccgttgg
    10681 aaatcgcggc gtgggacagc atcatcggat cgaccgggat gtgaccgtag ttggaaccca
    10741 tgaagggaga ggcgaatcgc ttcttagctt ccttcaacca cttttcgtca atgggcttca
    10801 tatcggcggc cacgtcgctc atgccctagg gagggaagga ggaggtattt gcattctgcg
    10861 cctgaatagc aaataatgat atgccccgct gtgaaatatc ttaaccatga ccggtgacct
    10921 ggggagcatc gacgttccgt cgttgagatg ggagcagccc aagtggaccc aacggatgca
    10981 tcgtctggtc tctggtgaga ccgtttacgc cactttggag tggccgcagg ccttccgctc
    11041 caccggcctg tccatctccc gcgagggacg ctactccttc aaacgcggtg gcttcctgca
    11101 cccgttcata accgtgcgaa gacaggagtt cgagatggag cacgctaaaa tgactatgga
    11161 ttggaaagga aatggagagc tggtcttcac caacgcccag cgattcacgt tcacccgggt
    11221 ggccatgtcc cgcttcgatt acgaggtgac cgatcatcgc ggggcgcaca tgttctccct
    11281 gaataaaaaa atggccgcgt tcaagcaccg tggagaggtg cacatatccc cggctggcct
    11341 gagccaccgg gatatcgcgc tactcgttac gttgggatgg tacctggcgg tgatggtcac
    11401 cgaggacgcg gcggcggcct ccggagcggc ggcagcgggc ggttgatcgc tccttcttct
    11461 ccatcgcctc aaggcctgat gcccgcctct tcgaccaggc gggggatgat gtcctcccag
    11521 gcgatggcgg tgatgtgcac cccgtgaacg cctttgatgg acgacagctc gttcatcatc
    11581 tccacgcaca tgcgaatgcc ctcttcctta ggatcggacg atctcctcaa gcggtcgacg
    11641 agctcgtctg gaacgctcat cccggccacc ttgttcttca tgaagagcgc ggccttgtgg
    11701 gagcgcagcg ggatgacccc ggcgattatg tggacctttt catgaagctc cttctccacc
    11761 accaggccca tgaacttttt gaaacgctca acgtcaagga cacactgggt ctgcacgaac
    11821 tgcgccccgg cgtccacctt cttccccaac cgggtcacgc ggaactcgaa ggggtcggcg
    11881 aacggattca ccgccgcccc gagatagagc tgcggcggtt ccgggagcgt ctcgccggac
    11941 cagttgttcc ccttggtcag attgcgcagg accatcagct cctggatgga gtcgaggtca
    12001 tagacgttct tggcctgggg atggtttccg aacacctgat ggtcgccgct gatgcacagc
    12061 acgttcctga tgcctagcgc gctggcgccg atgacgtcgc tctgcatggc gatgcggttg
    12121 cggtcccgac aggtcatctg catgaccggc tccaggccct cctggagaca tatcacggaa
    12181 gaggcgatgc tggacatacg cacgttcgcc gcttgattgt ccgtcaggtt gaaggcgtga
    12241 gcgctgccct tgagcaggcg agccatttga cgaagcttgt ccacctcgca tgaacgagga
    12301 ggaccgatct cggcggtgac ggcgaacttg cccgcgtcga gcgttccctg cagttgagat
    12361 acgctcatgg ttcgcccctc catccattct gcgccgctcc aggcagcgcc tcctggttca
    12421 cgacgcgcct cggaccgccg ttgcgactgg ccctccagtc cttagggggg atgttgacgt
    12481 tgagcaggtc aagccttccg ctgcgttcca gtgacctgat tatctggtcc caggcgcagg
    12541 gcgtttcctt cgacacctcg cagagaccgt tctggcttcc tccgcaaggt ccgttcagca
    12601 ggctcttggc gcagcgggcg atcggacaga tccccgccgt gagatgaatt atgcagtcgc
    12661 cgcagccggc gcatttctcc acgaacacgc ccatgccttc cggggccccc atgttggagg
    12721 tgttcactcc cgggacgacc atggcttcgg gaccgtggtc ctgcaccacc tgcgctccga
    12781 cgccgcaggc catgctgacc acggtgccct tgaatccgtt caggggggtc aggaactcct
    12841 tctcgcaggc cctttccact gttagcgtat cgaccttcca gcccttgccc ttgagctcgg
    12901 aatgcaacgc caacgcctcg gacaacgctc tggattcctt ctcccctccc gccaggcaga
    12961 tggccgtaca ggacctgcat cccagtacca gtatctcgtt cgaaccgtcc agcatcccca
    13021 ggacctcggg cagcggcttc ctctcggcga ttatcatgct tgaccccctt gctcccttat
    13081 ggtagcgcgc atttcctcta ccgccctccg gaaacgagcg gactgttgct cggccaggtg
    13141 gaccatggcc accctgccct tggtcaatcc gatatcttgc acggtccttt ccaggatcaa
    13201 ggaccggcgg gcggcgacct cgctgccgta gtgatgggcg cagttctcca acaggcagcc
    13261 gacgataaga acgccctccg ctccctgacg gaatgagcga agcacctccc attgctcgac
    13321 ggaaccggcg caggggacct ctctgacgat gacgtcgtcc agccctcctt cctccaacgc
    13381 taggagcgcc gcaggcattc cggagcggga acagcagtaa cagacgatca tttcagaccc
    13441 cctcccatct tgacgcttcc ggcctctgcc cggaggtccg agggcggcat ctcaatagcc
    13501 aggctcgggc acatcgataa gcatagaccg cagccctggc atctctcggc ggatatggac
    13561 aggccctctc cgctgaaata gggagcgccg tacggacaga cgcgcaggca agtgaggcat
    13621 ttcgagcacc tctcctggtc tatcgcggcg atagggaccc tgggaagagg tgaaccgatg
    13681 tccttgacga gagagcagac gatcgccctg gccatcccgg ccgggtcgcc ctcgtgatga
    13741 gcggacagag ccgaaccgca taggaatatg ccaggcacgc cgctgtcgcc cggtacgatg
    13801 cctatcgatc tgcgggatga tggcattccg aagaccttca gcacctcgtc ggccgccttg
    13861 gggcgcgaag atcgaacggt gaccagctct ccggtccaga tcttgaccgg acgtccaaga
    13921 tgttcatcgt tcacggtgac cgaagcgccc tggacctcga tctctgacgt tctgagaaag
    13981 accacgccac gcaactggag gtcccgatac actatctcgg caactccgga gaacggcgtc
    14041 tcctggacga cggcgtagac cttgccgccc ttggacaggg cgccctcaag ctctgaaacg
    14101 aaagaacgaa ggcattcctc gcctccggcc aaggccacca cggcgtcgcc ctcccccagg
    14161 ccagtcctgt caattatcac catcggatcg aacgagagaa gggcgtgacc gaactggtga
    14221 agcacctctc ccgcttccag gacgaaattg ccccttcccc cggtgagccg cgcttcgttc
    14281 cagtcgacct cttccggagc cagacgcacg accttgaggc cctcggccaa cgcctgttca
    14341 tacgcggcgt ccgcggagat cccttctccg accagcaata gctcgtcgct cctcgcctcg
    14401 gcggagaact tggcctcccg ctcgtccagt actttggcca aggcaagctc ggcggcgtga
    14461 gcggtcctga cctggaacgg caccaccgcc actcgggtcg gaggtatccc ggccagggcg
    14521 gccaggtcct ggtacctctt cagttcggag gcggcgcagc ctaggaccag gagcgcctgc
    14581 gtcgtcaggc cgagaaggtg aagctgtatc aggtcccggc cctcggtaga gcagcatcta
    14641 ggaagtatct cggagtgtcc gacccgagga tgcttcatga gaccccggta agcgaccaga
    14701 ttggccccat gcgcccggca gatgaacacc gccgccttca tcggctcact catggtccgc
    14761 ctccagatgc ttcatgacct gctgagcgac caggatgccg tcggccacgc aatggcctat
    14821 gtcctttgag ccacggcagc tcccggccag gaatatcccg cggtcggagc agttatcgtc
    14881 ctgcaggtct ccccaggggt cccggggaat ggccagctgc gataaggtat catcttccag
    14941 atcgggcacc aacccgaccg agagaattac ggaatcgaag ttctgacaaa tgatatcgtt
    15001 cccggaagca tagcgcaccg agggacggcc gccctcggct agcacttcgg ccgggcgaga
    15061 gcggaccacc tgtacgtcag tggtcgccag ctcccggagg agctcgtcgt ccgagctcaa
    15121 tccccgccag tccatcatga acatggtgat cgaaagctta gggaaccgct ccttgagggc
    15181 caacgcctga cggagggagt atttgcagca gaccgaggag cacttttcag ttcccatccc
    15241 ggaggagcgg gagccgacgc agaggatgaa agccacctcc ttcccgttcc cgatgtccgc
    15301 atcccttctc ccttccagga aggattccag ttccatggag gtgatgaccc cgggaacctc
    15361 gccatatccc aggcgtttat ccttggaggc agggaactcc aacgaaccgg tcgctaccac
    15421 caccgcgctc ccgttcacgc tgagatgctc ttccccgaag aggtcgatgg aaccggtcgg
    15481 gcagacgctc acgcacctct cgcattccag cccatggatg gagcgacatg cgttccggtt
    15541 caatcggatc ctgccggcca ccttggtcat ggctccggtc gggcaggctt ccgtacactt
    15601 gccgcaacga gagcaccttc caacatcgat ggcctccttc gggcgcacca gatcgaagcg
    15661 gtaacgcccg ttgttgcgct ccacctgctc cagctccacc agggtgtgca ccgagatcag
    15721 ttcggacgag agaacctgcg atcgcaggcg gtgcacccgg cagacgtcgc attgacgaca
    15781 atgaacgaag cctttgcagg acaggtcctg gacccttccg cccagcgtct cgcgcttttc
    15841 cagcaaaacg acgctcacct ctctttcggc cagttccgcc gcgcaggcca gtccggacgg
    15901 gccgccgccg aggaccacca ctttggctat gccctcgccc cctctgatgg tatgaagaaa
    15961 gtgcctggcg cagaggctgg tccatgtggt ccggagaggg cgtccatcac agatttgcca
    16021 gcattagcca gatattaaaa acttttgcgg tgcaccatac cgtttaagtc ctggccgcag
    16081 gatataccca cgtgcgcgcc gtggccttca ccgtggacgt ggaccgggat gtcaacctgg
    16141 cctgtcaagg ggagctatgc tccatctcca acgggggaaa gctcccccgc ttttcttcgt
    16201 ctgccaaggg cctggcgctg atggccggtc tcctggaaga gatgggcatc aaggggacgt
    16261 tcttctggga aggtcggacg gcggaagttc tctcggagag catggacctc aaaggcctga
    16321 tgaaaaagca tgaggtggcg ctgcacggtt acgatcacga ggacttcgct ggaaaggaga
    16381 ccggtttacc attggacagg cagagcacgc gtgccgtcct ggaaaggggg accggggtcc
    16441 tggaccgggt cttcggaaag gaagagcgag gtttccgcgc gccgtaccag agagtgacgg
    16501 acgttcttct ggacgagctg catgctagga ccttcctgta tgactcctcg gaaacggcgg
    16561 aactgtcgga tggccaggtt cgtccttacc gcaataaaaa tggactgccg gaggtgccag
    16621 tgtgctggtc ccgggacggc cggggaaaga ggatcgtctc ctatctttgg ccgtatcacg
    16681 agggaaaacg accgatatcc gactatctgg acctggcaga cgggttccaa gagggtctgc
    16741 tggtcattgc cactcattcc tggcatccgg tggagagcta ctgctcgggc ctccgtacat
    16801 cagatgatgt ggagaaggga atcgcggacc tgagatcgct gctggagcat atcgagcgtt
    16861 caggatgcga gctcgtcagc attgccgacc acctgcggag gaaggatgcc ctgtaatccc
    16921 gcttaccgcc aggcgatcat gctggcctgg gattccatcg ccgggatccc ggacaaagaa
    16981 ctggcctccg cttcaaaagc agatctgcgg ggccgggagc tggtactgca gaccgtggga
    17041 caggagacag tcgtcgatct ggccgatcga tgcttgaccg ccccggacgt tttaggtggt
    17101 ggatggggac tggcgacatt gcatcatctg aaaggatgcc tgacctggaa gagggatgag
    17161 gagtggacct cttttgacgt tatccccacg ggacgcccgt tcgccgaggc tttcaggcaa
    17221 cgtgcgctga tgccgttggc ggagcgttac ggtagatccc cggacgcctt gctgaaggac
    17281 ggtgctgcgc tcggtggaac gaagttcgat ctgggggacg cggcgatcat gatccaggcc
    17341 ttccctcgat tgaagatcgc catcgcggcc tggcagggcg atgatgaggt accaggaaaa
    17401 gcggtcatgc tcttcgaggc aggaggagcg agaacgctgc cggccgaaga cctggccgag
    17461 gtcgggatta gcatcgccca ggcgattctc agtacaggcc ggtgatcttt ccgtcctcat
    17521 cgatgtctac gcctagcgcc gatggctgcg acggcagccc gggtatcagc attatgcgtc
    17581 cgcatatcgg aacgacgaaa ccagcccccg cggacacgaa tatctccctg atggtcagct
    17641 cccagccggt cggcgcaccc ttcatttgcg gtttatcggt aagtgatagt tgggtcttgg
    17701 ccatgcatac catgaagttg ccctgtccgg actcctcgat cacccgcagg tgcctctgcg
    17761 cggccgtctc gtactccacg acctgggcgc cgtacatctc ggtggcgatt atccttattt
    17821 tttcctttat cgggagctcc gtgtcgtaca ggaagcggaa atcgctttca tccttttcga
    17881 tcgcttccgt aacttgatcg gccagctcct ggccgccggc gccgcccttt tcgaacacct
    17941 cagaaagagc gcaacgcacg cccatcgcgc ggcaatgctc cctgatcgtg cgcacctctt
    18001 cctccgtatc ggccgggaaa tgattgatgg ccaccacgat cggaactccg aagtggcgca
    18061 ggttctcgat gtgcttgtcc aggttggaga agcctttttg caaggcgtcc aggtcctcgc
    18121 atcccacgga cttcagggga cagcccccgt gcatcttgag ggccttgatg gaacaaacga
    18181 gaacggcgca gttcggtcgg aagccgtcgt tccgacaaac gatgtcgaag aacttctccg
    18241 ctcccaggtc agcaccgaaa cccgcttcgg tgacgaccat gtccgcaagt ttcaaagcgt
    18301 acttggtggc gatgatggag ctgtttccgt gcgctatgtt ggcgaacggg aaaccgtgaa
    18361 tgaagaacgg ctgcccctcc aaggtctgca ccaggttggg gtggatggcg tccttgagca
    18421 aagttgccat tgctccgacg cagcccaggt cccgggctcg caccggctga ttatcgtaag
    18481 tgtagccgac caagatccgc cccagacgct ccttgaggtc ggtcattccc gacgtcaaag
    18541 ccaatatggc gcttatctcc gaggccacgg tgattatgaa gccgctctcg tgcggtatcc
    18601 cgccttcctt gcgtccgcct aggccgacga cgatgttgcg cagctcccgg cagttcatgt
    18661 cgatggcctt cttcaggaag atgcgtgtgg gatcgatgtt cagctggttc cccatggcga
    18721 tgtggttctc cagtatggcg gaaagaaggt tgtgggcggc gcccacggcg tggatgtcgc
    18781 cggtgaagtg aaggtcgatg tcccacatgg gatagacctg ggcgagaccg ccgccggtgg
    18841 cgcctccctt caatccgaac gttggaccaa gggatggctc acgtatcgct cccatgacct
    18901 tgtggccctg ttttcccagg gcctcgacca gaccgatggt ggtgacggtc ttgccttcac
    18961 cggccggagt gggggtgatg gccgtgacca ggatgagctt cccgttcggg cggtcatcgt
    19021 aacgcttgag cacggagagc ggaaccttgg caatgtacct gccgtaggga acgagctcct
    19081 cttcagcgat cccgagctga acggctatct ggtcgatcgg gagcaccttg gcctcttggg
    19141 agatctcgat attgctcttc atgcactacc ttgagaaccg atatccagac cgagcttaaa
    19201 atggtttatc gcccggcaat tctttaatac ggctaaggca tcaagaatcc tggtcagcaa
    19261 atgggcgcaa gacttttaga gggcaaggag gtcgccgacc gcatcaggaa ggatttggcg
    19321 gtcaggatcg ccgcgctgaa ggagaagggc gtcgttcccg gactggcggt cgtgatcatc
    19381 ggggatgacc cagcttcagt ttcctacgtg accatgaagg gaaaggcctg ccaggacctc
    19441 ggcatgtact ctctcaccgt gcggaaaccg gccgacctca gcgaggacgc gcttctgcag
    19501 cagatagact atctgaaccg ggaccctaag gtgcatggca ttctggttca acttccggtg
    19561 ccccgacata tcgacgttgg aaaggtcatc gccgccatag acccgaagaa ggacgtggac
    19621 ggcttccacc cgaccaacgt gggcaagatg ctcatcgggg aggaggacgg tttcttgcca
    19681 gccacgccgt acggtatccg cgtgatgctc tcttcctacg gcgtagacgt caccggaaag
    19741 cacgtggtcg tcgtcggacg cagcaacatc gtcggcaaac cgatggccgc catattgatg
    19801 cagaaggggg tggacgctac ggtcaccgta tgccattccc ggaccaggga cctcaaggcc
    19861 ataacggccc aggcggacgt gctgatcagc ggcatcggga aagcgctctt cataaccgcc
    19921 gacatggtca aggagggggc ggtcgttgta gatgccggat cgaaccgtat cgatgatcca
    19981 tcagcaccca aaggctaccg cttcgtcggg gacgtggatt ttgacaacgt gaaggagaag
    20041 gtatcggcca tcaccccggt gccgaagggc gtggggccga tgaccatcgt gatgctcatg
    20101 agcaacactg tgctggccgc ggagcggtcc ctggaacgtc agaatcgtcc taaagtttaa
    20161 gtcccacttt gtatgttcga gggttcgtta tgttgcggga atgcggcgag cacggatact
    20221 ttcgcgggga gacctgcccg atttgcggtg aaccaggcaa gttcctgtta agcgagcagg
    20281 agctggacca gttgggacgt actctggccg gagtgctcag gcacttcccg gaacgcttcg
    20341 gactggacat ggacgagcag gggttcgtca gcatccgagg cttcataaac gccctccggg
    20401 acagcaaccg ccgctaccat tggctcaggc cgcaccatat tgtcgccata atcgagaccg
    20461 accccaaggg aaggtaccag atcagcaacg atctgatgcg ggcgacttac ggccactcct
    20521 tggaactgga cctcaagctg cccaccgaga acattcccga tcacctgtac tatccggcca
    20581 cgccggagga ggcggacatc atcctggaga cagggctccg accgtcggac cgcaagatgg
    20641 tgcacctttc gagaacgtac caggacgccc tgaacgccgg caaggtaaga gttgaggcgc
    20701 cgatcatttt ggagatagac tccgcggcgg ccatcgcggc cgggaacgta atatcccagg
    20761 ccggcaagac cgtgttcctg gcccaagaga tccccccaga gttcctctcc cgtaaggaag
    20821 aggaagaagt cctctgagga ccttttctat ttttttagaa cggccgtaag gccgaaaatt
    20881 agaaaacgct tagaaaataa agatcaaaaa gcgctgaact gagcgttcag acgctgatgg
    20941 tgcccacgat ctgcaggacc tggaacacga tggtcaggga gaacaccact aacaacggaa
    21001 ctatagcgga gtccaaagtg gccagaacct tcttggagcc cttgttggaa gcggaaatga
    21061 gctccctgga agaaagcagc atgatcagca gtatcgcgat gagcgccccg cccacgccta
    21121 cactgaccgc agtggttatg gacacggcgc tggtcgccgc ggccgtagta gctgcactca
    21181 cgagtatcaa agacatgata tcaagcccac gggataccta gtataaaaaa atatttggaa
    21241 gggtttcact ttttgaacta ggtgccatat caatttccac gatcggcgaa ctcccggtca
    21301 cacttaaatc gacgttcctc gtttgatgtc ctcgtgttcg aaacggccga cgagatcctt
    21361 cgccgaaagg gcatggtcgc ctacgaccgc cacgccatat cctgggagtg ggaaggatac
    21421 cagccgatat tggtcaccta cgaccagaag gccaaggagg tccaggagct cacggaccag
    21481 ttccggcccg gggagcgctt cgacctcctc atttcggacg ccaggcgctg cgttggatct
    21541 ttcattgacg gtgaatacga accgtgcaag atgcgcaatg tcgtctccgg gcagttcgat
    21601 caatgcccgt tgtgcgcttc cacctggata ccggtgcaga actgtgtgtt cgagccggag
    21661 tgcgatggca ctaacatcac gaacgagagg tgcataggca agggcgggga catctgcgcc
    21721 aagcccactc acgtctacgc cgcattctac ggcgacctgg tcaaggtggg aatgaccctt
    21781 tccacgagat tcatggagcg ggccatcgaa cagggggcgg atgcgatagc caggttggga
    21841 acgtacccta accgcagagc ggccagggac gctgagaacg ttctgtccaa ggcgctgcac
    21901 gccacgcaat gggtacgcaa gaccaccttt ctcaaggcgc agggctcgat aagggaccgc
    21961 gaggtctatc aggcgcgcct ggacgctctg ttctcgtccc tggacggtgt ggccaccgat
    22021 ccaggggagt tgaacatgct ggaccgatat cccttactgc cgtacgaacc atcgaaggcc
    22081 gtcttcgccg aggtgaccgg tcggcaccgg ggagaggtcc tgggatgcaa gggaaaatgg
    22141 ctattctacc gcctcaagga cggccgaacg atgctgctga acatgtccag cgtcccttcg
    22201 cgttacatca ccatcagcct ggcaaacata aataaaccgt aacaatatcc attcccctcc
    22261 gtcaagttaa cctaaggtgt catcatggtg caagttctca aaccggaaga ggtcaccgag
    22321 aagtacggaa ggctgttctg ccgaggcgtc ttcacattgg tggacgagag gaacggcgtc
    22381 gcccaggtca tagaggaatg ctctgccaaa ggcccggtgg aatgggacgc ctgcaaccgc
    22441 aagcgggcag gcggggcgat caccaacatc accgtggaag gcaacaccat catcatggac
    22501 accatcatcg gcgagggcga gctgcacttc ggcccggcgt ccaaggacct cggaggccag
    22561 gggctgcgct cgctggtcgt tgacggagat aaggtccgca ccacctgggt cggcctggcc
    22621 ggcgccagcg tgggcatcgg agcctgcatg ccccaggggc cggggaccat cgccacggag
    22681 tatccggacg atgtgaagat cggcggcgcc cacaaggtgg aggtgacggt gatcaccccg
    22741 aagctggttc gggtcataat ctccgtcgac gataccgaca ccaaggagaa gggagcgtcg
    22801 tggtccatga tgctcaaggc ggcccgcgaa tgccccgtcg gcacgttcct gcagcacaag
    22861 atcatccagc tcaatccgaa cgttccacag aagaccacca actgctcctc gtctggcgtt
    22921 agcttcgcca tcaaggagag cgagatcccg gccctgctgg attacttcaa ggaggcgttc
    22981 aggaagaaca cctactccca ggagaccacc atggcttact atgtcggtct gcgcatcccc
    23041 aaggacctgg aggagtacgg ctggaacgct aaaaaggtga tctacaagcc gcaggatgct
    23101 ctggacgtcg ctgaacgaac gggcgtccag gtggtggaga taaccggcag gcgtggcacc
    23161 atcggagcgg tggcggccat cggatgcttc gacctgggct tgaaggccgc cggactcccc
    23221 gaggacttcg aaaactagaa tatcaccgac ttggtaggta cccctgatgt ctaacgagat
    23281 cacccgcgtt ttcgcgaaca ccgcttacca gacctatgag aagcggctgt tcaaggaggt
    23341 gatggagggg gacatcccgg aacacgtggc catcatcatg gacggcaacc gccgattcgc
    23401 tgaggagatc gggctggcgg tccatgaagg acatatcaag ggcaaggaca agctggagga
    23461 ggtcatggaa tggtgccagg agatgggcat caaggtcctc accgtctacg ccttctccac
    23521 cgagaacctc aaccgggacg agaacgaggt ccattacctg atgcagctct tcgaggagag
    23581 cttcctcaag ctggcggagg atcaacgaat ccacaagaac cgcatcaagg tcaccgtgct
    23641 gggtcagcgg gagctgcttc cggagaaggt cataaaggcc atcgaggtcg ccgagaaccg
    23701 caccaaggac tatgacgatt acttctacaa catcgccctg gcctacggga gccgccagga
    23761 gatgatcacc gccatcaagc gcatcgcatc caaggtgaag gacggtgagc tttccgtcga
    23821 tgacatcgac gaagagacct tctccagctt cctgtacacc gccgacttca aggatccgga
    23881 cctggtgctg cgcacctccg gtgaagaacg agtttccaac ttcctgctct ggcagttagc
    23941 gtactccgag ctgtacttca ccgacgtgtt ctggcccggc ttccgaaagg tggatttcct
    24001 aagggccata cgcacctacc aggataggca gaggcgcttc ggaaagtgaa aagggcggag
    24061 tataaatatc tccgattgtg tcagcgtgcc agtgagctta gtcatgagca aagaggacat
    24121 catattcctg cacgcgccga gcgtctacga cttccggaag gagttcctgt tctacggacc
    24181 ggtcagcgac atggtcccct ccacgccggt gttcgagatg tacccctttg gattcacgtc
    24241 catggcctct cacctggcca ggaacggcta caaggttcgc ctggtgaacc tggcgagcat
    24301 gatgctcaac gaccgcaagc tggacgtgga gaagctcata tcgaagctca aggccaaggt
    24361 gttcggtatc gacctgcact ggctgccgca cgcccacggc gcgctcgaga tagccaagct
    24421 ggtcaagaaa catcacccgg acgccaaggt gctcttcgga ggtttctcat ccacctactt
    24481 ccaggaggag ctgctgcgtt acccgcaggt ggacctgatc atgaagggcg actccaccga
    24541 ggaaccgctc aggcagctta tggaggcgct caagaacgga acgccgttgg agaacgttcc
    24601 caacctcagc tggaaggacg agaagggcga acatcataac cccataacct acgtcccgga
    24661 ctccctggac taccaggacg tcgattacgg ctggatcgtc cgctcggtga taaggcacct
    24721 ggacctggaa gggcacaagc cgttcaagga ctgggaccgc tacccgatca ccatggtatt
    24781 ctcgatcaag ggctgccacc tcaactgcac ggtgtgcggc gggtcgtgcc cggccatgca
    24841 caagttcctc aaccggcaga agccggcgtt ccgctccccg gagaagctgg cgcaggacgt
    24901 ttacaacatc cagcaataca tcaaggcccc caccttcatc gtcggcgatc cccgccgggg
    24961 cggcctggac tacatgcaac ggttcttcgc cgaggtcaag cgcctgggcg tgacgaactc
    25021 cctggtcttc gagttcttca cccctccgga cgaggagttc tataaactgg cgtccacgca
    25081 caccaagggg ttcgccgtgg agatctcgcc ggactcgcac gaccccgagg tgcgcgaggc
    25141 cctgggacga aagtattcca acgaggagct ggagacctcc atcaagaacg ccctgaagta
    25201 cggtgcggag aggttcgacg tgttcttcat gatcggtctg ccgaagcaga ccagggagtc
    25261 ggccgtcaag agcgcggagt acgccaagac gctctatctc gccgctgaca aggacccccg
    25321 gctctgcgtg ttcatctcac cgctcgcccc gttcctggac ccggcgtcct tggccttcga
    25381 ggaccctgag cgcttcggtt acgtatcgtt agccagaacg ttggaggagc accgggcccg
    25441 tttgacgtcc ccgtcctgga agcacgtgct atcgtacgaa acgaagtgga tgaccaggga
    25501 cgacatagcc gaggtctcct acgaagcggc ggacgccatc aatagagcgc gtttcgaatg
    25561 cggcctgatc gacaaggaag aactggatta tcgcctgaag cgctcggccg aggcggcgga
    25621 catgatgaag cgcgtcgacg ccgccatggt cataaccgac ccggaagaga agaggaaggc
    25681 cttccaggag ctgcagagac gttccgagga gctcatggag agcaccatca cccacaagcg
    25741 ggagatggaa tggtccgcga aagggcttct atggagcgtc ccccgggcgg cctgggccgt
    25801 tctgcgcggc gtctaaggga acatcggccg gcagcggatg agattgttca tccggcgcgg
    25861 tccgagcacc ttcatggccg tttccgtgcg ccagacgctg ccgaagcaca gttccgccat
    25921 gaccttcgtc ctggccgcgg tccgcagagg cttgtagacc tgcttgcgcc attccgtctc
    25981 gtagtcggtc agaggcgttc cctgtagaac gttggccgcg gcgatggtcc cggccacctt
    26041 tccggtgatg cgggccatcg gtataccgcc accgttaacg gccatcacct ggccggcggc
    26101 gtccccgacg atcatcgcct gaccggagac ggtcctcttg accggcttgg acatgggaac
    26161 taccttaccc tccggttttc cggcggtaag gcccctgaac ttcacgaacc cctcgaagta
    26221 ctcgttaacg gtcatcctgg caaacttttt cgataccccg agaccaacgt tggcgcatcc
    26281 ctttttgggg attacccagg cgtagccgcc gggagccacc gtgccgaagt acatctccgg
    26341 caccggctcg aactccccgg gcacctgcac ggtgacggcc gggcacaggt cggcagagcg
    26401 ttccagcccg aaggcctttc cgaccatgga tagcggcccg tcggccccca cgatgacctt
    26461 ggcccttacc gagaggtcat cggtgcgcac catgccctgt tcgaccttga gcacccgctg
    26521 cccggtcatg atctccgccc ccgccttgct cgcttgcgag gcatagaact ggtccagccg
    26581 gtcccggtcg gtcgtatagc cggtgaaggg aacctcatat ttggtgttct tcggggagaa
    26641 gatgcgtatg gagctgaact tgagggagac cagatcggaa gggacctcga agatatcgga
    26701 catgtccccg gccaggggga atatgttcct catctcctca aggtcgggca tcagctcccc
    26761 gcagcgaacc ggaacgccga tctgagcgcg cctttccaga accagaacgc tggccccggc
    26821 ctcggcggcg aagcgggccg tggtggaccc ggcgggaccg gctcccacca ccactatgtc
    26881 gtaattaagc tccttgacca tgtgattctc ctccgaacgt cgtcagtagt ctcgatcgac
    26941 taccttggcc gccagcctct gaagccccac cttgtgttcc gagtccggga ggacctccag
    27001 tgaccttagg gccttctcag cgtactcctt ggccttctgc ttggacctct ccaccgcgtt
    27061 ggtgcgggag atgagggctg aggcctcctg gatatcctgc tcatccttgg ccttcttgtg
    27121 gaaaagctga tagaggcgcg ggcctaccgc agggtcctcc atggcatgga tcaatggaag
    27181 ggtcgcctta ccctcgaaga agtccaccat gcggggcttg cccaatgatt tctcggtgcc
    27241 cattatgtcc aggatatcgt ccactatctg gaaggccatg ccgatgttga gcccgtattc
    27301 gcccagggcg tgaatgcggt ctggttcggc tttcgccagg tacgccccga tgcgagcccc
    27361 ggccattatg ggcttggcgg tcttgccctc gattatgccc agatagacgt ccagggaggc
    27421 cacctcgccc tccttctcga actgaactat ctcgctctcc gcgatggccg tgcaggcctc
    27481 ggcgaccagg ctcacgatct cctcgttgaa gaaaccgccg atggcgaagg ccttgacgaa
    27541 caggaagtcc ccgctcacca acgcctgttg cagtccgaac ttcttgtaag ctgacaaacg
    27601 accacggcgc ttctccgagc ggtcgttgat atcatcgtgt atgagcgtcg cggaatgtat
    27661 catctcgaag gccgcggcga tcttgaccgc ctcgctgacc tccttgccac ccgacgcaag
    27721 ataagataag atggtgaccc cggggcgcat gcgtttgccc ccggacgata tgacgtaatc
    27781 gcatatctcg gttagaactg gctgctccga gcttatgctg cggcggatct cctgctccac
    27841 catctgcagc tcatccttta ttgaggaatc ccagctctga gacatcgttc gctcgatatg
    27901 gtaaatttat acttaaccgt tactggcttt ttaaacgaaa agaatggcca gcgtatccgc
    27961 cgcttggtaa aaaaagaaga gaatggataa agggttttca ggcgaacaag gcctgggcgg
    28021 cgtccttgca aagctggatg aacggctcgg ggaacacacc gatgccgatt atggccacca
    28081 cgcagatggc caccgcggcc atcatgctct tgggcagctt cagcttctcg gacggggcgc
    28141 cctcttccag ctcgtccacg tacatgtact tgaccacgcg agcgtagtag tacagggata
    28201 tggcgctgtt tatgataccg gccacggcca accagatcat ccagtcggct ccgtccaccg
    28261 tgcccatgat gggcgaggag aacaggacga ccttactggc gaaaccggcc agaggcggga
    28321 tcccggccag ggagaacagc agcacggtca tggagaaggc catgaagtta gacctcttgg
    28381 ccagtccctt gtagtccgcg atcttctctc cgatggccac ggtggccagg gtggccacga
    28441 cgatgaacgc gccgcccttc atgaaggcgt gggtcagtat gtggaagata ccgccggtga
    28501 ccgcgtactc agttccaacc gccaccgcga tcaggatgta accggcctga gctatgctcg
    28561 agtaggccaa catcctcttg atgctggtct gttgcagggc cgccaggttc cccacggtca
    28621 tggtgactat ggccagcacg gccaccacga tctcccagtc ggccttgatg gccagcatgg
    28681 cgatgaggaa gaacttgaac atggccacga aacccatctt cttggacccg gccgccagca
    28741 gggcggtgat ggtcgtaggc gcgccctcgt acacatcggg ggcccaggag tggaacggga
    28801 ccatggccac cttgaagccg aagcccacga tgaccatgac cagggccagc cagagcatct
    28861 ccttgtactc ggtcagagtg ccgaccaaag ctccgatctc cgcgaagctg gtggttccgg
    28921 tgaccccgta gatcagggag ataccgaaca gggtgaaggc cgaggagata ccgccgaata
    28981 tgaagtactt ggtcgccgcc tcggtcccct tgatgtcctt cttgcggaag gccaccaggg
    29041 catacgagga aaggctggtg atctcgatgc cgatgtacag cacgaacagg tcggtagcag
    29101 aggccaccaa catcatgccg acggtggcca gcaggaccag ggaatagtac tccgcgccgt
    29161 gcttctcctt ctcgatgtac tttaccgagg cgagaatgac cacgaaggcc acggacagga
    29221 acaccatcat gaacagggcg ctgaagttgt ccagtaccag cagtccattg tcaaaggcta
    29281 tcgaacccgt gccatccaga tagaacatga gcacggccag catggacagg ccgacccccg
    29341 cgagcgaaac ggccgccaag aaccggttgt ccttgatcaa tagatttaca gccggcaggg
    29401 ccagcgcgaa cagggccacg attatctcag gatacaatgc cgtatagtcc acttagatcc
    29461 ctcccaggag gcccagtacg gtgccaagag cagggcgtat gtagtccatg accatggcgg
    29521 ggaacattcc gaacagcacg atgagaccgc agagcaccgc caggggcagc gcctcgaacc
    29581 agtatacgtc gtgcaggtgt tcggtgtcga cctccttggt cagcggtccg aacagggtgc
    29641 gctgcatcgc ccatatgtaa taggcggcgg tgaaggcgat gctggtaacg ggtatcagca
    29701 acaaccagcc gaaggcgtcg aaggtggcgg tcatgatgga gaactcggcc acgaaaccga
    29761 ccattcccgg gagtccgaga gaggccatga agccgatcat catgaacacc gcggcgatcg
    29821 gcatctttgc ggccagcccg ccgaggcggg ggatgttcct ggtgcccgcc ttgtgctgta
    29881 tcacaccgca catcatgaag aggacggcgg tgatgagacc gtgggcgaac atctggaaca
    29941 caccggcggc gatgccgatc tcggtgaagg tggcgaaccc tagcagcacc agacccatgt
    30001 ggctgatgga ggagtaggct accatcttct tgaggtcctt ctgggcgatg cacatgatgg
    30061 cgccgtagac gatggacaga atggccagga tgaccattac gatctgccat tcaccggcac
    30121 cgtccggcaa ggccggtaaa gcgacccgta tgataccgta ggcacccatc ttaagcagca
    30181 gaccggccag caggaccgat ccggcggtgg gggcctcgac gtgcgcatcg ggcagccagg
    30241 tatggaacgg gaaggtaggc atcttcacgg cgaagccgaa gaagagcgcc ccgaacacca
    30301 cgatctggaa cgtcagaccg aacaacgggg atacggagtt gatgtcctcc attccgaagg
    30361 aatagaaccc gttgaacgag gcggcctcga agtacagggc gaagatacct agcagcatgg
    30421 ccaaactggc gatgtgagtg tatatgaaga acttgatcgc cgagtacgag cggcgcggac
    30481 cgccccacac gctgatcagg aagtacatcg ggatcagcac gacctcccag aagatgtaga
    30541 acaggaagta gtccagggcc atgaagacac ctagaactcc cagctccagc accagcagga
    30601 gggccatgaa ctggttggtc cgatggtcca cgtcccagga gaagatgacc gccaggaaca
    30661 ccagcagcgt gctcaggaag accatgggca cgcttattcc gtccacgccc agtatgtagg
    30721 atatgccgag ggaatcgatc caggtgaatg actccctgaa ctgataaccg ccggcggtct
    30781 gaacgtactg ggtgagcatg aacagggaca gcagcatagg tatggccgag aacaccaacg
    30841 cggagatctt ggccatcttg gggttcttac ccagggcgaa ggtgaccact gcaccgacca
    30901 gggatacgag caacatcaga gatagtatcg gtatttccat gggatcacct cagcactcct
    30961 acgacgtaga gaaggattac gatcaccgat acaccgatca ccagcagggt ggcgtagctc
    31021 tgcacgaagc cgttctgcag cttgcgcgtc actccaccca tggccatcag gaaagcggct
    31081 atgccattca ctatgccgtc gatgacgtag cgatcgaact tgtcgagcag cagggagaag
    31141 ccgtacactc ccacgtagcc tatcttgtcg taggcctgcg ggaacttgta acggtccagc
    31201 agcagctggt gcatggcctt ggggaatccc ttggacacga ccttctccgc cgatatcttg
    31261 ctcttataga agctgaagta ggctagcaat atgcctgcca ccgcggcgac tatggatatg
    31321 taggtaagcg gagaggtgaa cacctcttcc aacttctcgc cgatggtcag tacgtgggcg
    31381 tccccgtagt atatggcgcc gaagaagcca tccccgatga acagggagaa tccagaggcg
    31441 aaggccagag aggccaggat caccaacggg atcagcatgg cgataggcgc ctcgtgcttg
    31501 tgatgcccgt gctcggtggc atgaacggtg ccctcgttgg gcttgccacc gaagaccatg
    31561 aaccacatgc ggaacatgta gaaggcggtc atgaaggccg taagcacgcc cagtacccac
    31621 aagaccatga aggtcaggcc ggcatcgcca gcctcgaagg tcatggccag tacctcatcc
    31681 ttgctccaga atccggagag cggaggtata ccggcgatgg agatacagga gatgagcatg
    31741 gttatcatgg tcaccttcat gtacttgccc aggccgccca tcttggccag gtcctcggtg
    31801 tgcacgtagt ggataaccgc tccggcgccc aggaagagct ggcccttgaa gaaggcgtgg
    31861 ttcatcaggt ggaacaggcc ggcaccgaag gctatcgaac cggcggcgtg gtggccgtga
    31921 tgccacagga acgcaccagc tcccagcccc aggatcatgt atcccagctg agatacggtc
    31981 gaataagcga ggactccctt gatcttcggg gcgcacaagg ccatggtggc ggcgatgaag
    32041 gcggttatac ctccaatggc gcctacgaat agcgcaacct cggcgctggt ggcgatgatc
    32101 gggaaggacc tggcgaccag gtacacaccg gcgttgacca tcgtcgccgc gtgaatcaag
    32161 gccgaaacgg tcgtggggcc ttccatcgcg tcaggcaacc agtcgtgcaa cgggaactga
    32221 gcgctcttgc ctatcgcccc gccgaacagg aagaaggccg cgaaggccat catcgtgggg
    32281 tcggcggtgt ccagagcggc ccacacatca acgtagttga aggtgcgcag ctcggtgaac
    32341 aggatgaaca ggccgatcat gaacatgacg tcgcccaccc tggtgaccaa gaatgctttc
    32401 ttggccgcgc gggccgcggc gggcctctcg taccagaacc ctatcagcag ataggaacag
    32461 accccgacca gctcccagaa cacgaacatc tggaagaagt tgttggccag aactaaccca
    32521 agcatgacgc ccacgaacag gcatatctcg gtgaagtacc ggtgccgcct ggggccttgg
    32581 tcgtgtatgt aggcggtcga atagacgacc accaggaaag ctatgaagga gaccacgatg
    32641 agcatcatgg ccgccacgtt gtcgagatat acgcccatct ccagggtgta ctcattgctg
    32701 agcactaccc aggtctgact ggtgctgtat atccttcccg tggttagtag ctcataggcc
    32761 gtccacagcg ccaggaccat tcctgcgccg acaccgccga cggcgatgta accgttcagg
    32821 tcgcccagct tcttgcccag gaaggcgatg aagacgaagg ccagcagcgg cagaaccggt
    32881 atcaaccatg cgtattccag tatgtccatc tttaccacct cagcaggtta atgtcgtcca
    32941 catccacggt cttcctcagc ttgttgaggt tcagtagtat ggccagtgcg atcgtgacct
    33001 cggccgcggc aatgcctatg gcgaacaggg cgaagccctg gccggtgccg tccccgaagt
    33061 acgtggagaa cgctaccagg ttgatgatgg ccgcattgag cattatctcg atgcacatca
    33121 ggatctggat ggcgttcttc ttcagaagta ccccggccgc cccgatgacg aacaggaccg
    33181 atgtgattat caacacgaac tcgagcggga tcattcgtca tcatcctcct gggcgatgaa
    33241 cactccaccg attatgacag cgaagagcat cagccccaac attagaacgg ccgctccgta
    33301 gtcggtgaat attacggttc cgacctcggc ggtcttgatc acggtgttac cgatgtcccc
    33361 ccattcgatg gtgaacacgg agtacagcat gagctccaga aggagcccga ccaccagaac
    33421 cttggccact atggcctggg ttgagtcacc gcgcttcatt tggaccgcct cctcttgact
    33481 atgtcctgct catactcctc gcaggcgtct cccccgacca tccggcgctt ggtgagcatg
    33541 ataccgaaca ggatcaggac gttgatggcg cccacgtaga ccagtaactg gatcaggaac
    33601 aggtattccg cgttcaggaa tatgtagagc acagcgacgc cgacgaaggt cgccgccagc
    33661 caaaccacgc tgcggacgat atccttggag atgaccacca tggcggcgca tcccacggtc
    33721 agggcgccga atatcaggaa gaacagggtc gttccatcca agatcatcac aacacctcct
    33781 ttatgctaag gcacgatttc gggcacacct cgacacactg ttcgcaaacg acgcatttag
    33841 cgttgtcgaa cttggggtgc ttaatcggct tcttggtctt ggggttgagc tccccggtat
    33901 ccgccatctc gatcgcaccg gtcgggcagg tcttggcgca cctcgaacag gagatgcact
    33961 tagaaccgtc cagagatacg gtgtcgtgga tgttcggatc gttcttggcg taggtcttga
    34021 cctccccgcc agccttcatc tcagatagaa gggcgaactc gaagttcacc tcgtaaccgg
    34081 gtttgtgagc gtgctgcagc ttgaccgggt cgaatatgag accggcgcgg ctataggagc
    34141 acagttcgaa ctccggggtc acgatcatgg cgttggtcgg gcacatctcg gcgcagttgc
    34201 cgcacatcat gcagcggccg acgttgacct gcgggcgctt taccttgccc ttctcggcat
    34261 cctggtaatc caccatctcg atgcactggt tcgggcattc cttggcgcag cgggcgcagc
    34321 cgatgcactt gtccaggaca atgcccgggc gtccacggta attgtccggg tagatcagct
    34381 tctcccacgg gtatagtatg gtgca
//
LOCUS       DAOPZI010000014        31894 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1335_length_31894_cov_10.294701, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000014 DAOPZI010000000
VERSION     DAOPZI010000014.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 31894)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 31894)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31894
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1335_length_31894_cov_10.294701"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..354
                     /locus_tag="PKM11_04130"
     CDS             <1..354
                     /locus_tag="PKM11_04130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47727.1"
                     /translation="SLAVIGQTVIAGVWSAALMVPAGLAMSSLTKKKTYAAVGTFMFF
                     FGMMIVSGIFSDIARDWFLLDPSQVLYQTHTVIYGLELDDIVNRYLLAAMAFLLTVPP
                     VALVYYRIMRMEAGK"
     gene            351..1277
                     /locus_tag="PKM11_04135"
     CDS             351..1277
                     /locus_tag="PKM11_04135"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47728.1"
                     /translation="MSNVVEARLLSKWYGEVIGLNNFSIDVPKGITGIVGPNGAGKST
                     FFKLLTGNIKTNVGHLRVLGEEPWQNPALLAKIGFCPDYDFLPPDLKGREYLRFVAGL
                     HGMDGARKATRVNDVLGIVSMTKDADRVMGGYSKGMRQRIKIAGALLHEPQLLLLDEP
                     LTGTDPLIRKEIIDLVKDLNKVHGHDVIVSSHVLHEIERMTHQVALIYKGRSVASGDI
                     SEIRQLMSDHPHNIVLEGRGLVPLAQALLTKPYTSSIELRADRLGMYVRVDRPEEFFD
                     SLPELVAGTGCELERVESLDDDLESVFRYLVG"
     gene            1283..2023
                     /locus_tag="PKM11_04140"
     CDS             1283..2023
                     /locus_tag="PKM11_04140"
                     /inference="COORDINATES: protein motif:HMM:NF024091.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX47729.1"
                     /translation="MSFNFIGLRTVAAFSARKLLMNRRWMTVALLGALVALVMGYAAT
                     QDGVNMDSASELMVLLLLAFLLPVLSLIYGASMIRNEMDDRSIVQVITAPLDRRISYL
                     GYYIGLVVVLCLLITVVTVIGGAAFLIFSPVRDGGLQLIVTFIALQYLGVMVYSALFL
                     FLGTLMKQPIYLGLIYIFVWEGFVASIPGSIGKVTIRHQLQVIGNELTDYGSWTNGDW
                     AVSILALVLVTALLVLAGAYVLRQEEVS"
     gene            complement(2212..2811)
                     /locus_tag="PKM11_04145"
     CDS             complement(2212..2811)
                     /locus_tag="PKM11_04145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47730.1"
                     /translation="MADVPVEFGAWLGILLDTVPNVIIAIATLIIGFILAYVAGELVR
                     EVCCHFGRDRTVGISGSKVSIVAGKIAKALVFAIAAVFAIDVLIDSGLFGDGGTLVEN
                     YAIRVVIGLLVIFVGALMADLTAATVAKWIHGGSCELKETDPTRELVFLGLLVSVVMM
                     GLGIMTVDSPAVLLIFLAFLVIGSLMIFLEARRKICRKL"
     gene            complement(2911..3744)
                     /locus_tag="PKM11_04150"
     CDS             complement(2911..3744)
                     /locus_tag="PKM11_04150"
                     /inference="COORDINATES: protein motif:HMM:NF017373.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47731.1"
                     /translation="MVDLVDELSTMWDDFLLAVPAILAAIIVLIIGLLVAWVAGKIIK
                     MVVRKVGLERFFNQTATGRAFLSSGLYASNLASMLVMAFVMIFFIVLSIQVLDMSGIF
                     GDYLTGLANYLPKVFVGVLVLVLGAFFADFLSSFIGRIVRPMFPEGKQNIAEMLKNLL
                     FIGLIAFVVLLALNVMLLTGALVYTLVLGFVIIGVGILLTDALIKSVADEHPDFKEVA
                     GYAKFVLYAIFLIIGTGAIFATFPGVTGIIANISWAFAIAMALMLVPVAFAMTKKMAK
                     P"
     gene            complement(3861..4478)
                     /locus_tag="PKM11_04155"
     CDS             complement(3861..4478)
                     /locus_tag="PKM11_04155"
                     /inference="COORDINATES: protein motif:HMM:NF025605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HNX47732.1"
                     /translation="MTVTKEILPEEMESAKERILAAAFALFAEKGFDGTTTRSIAERA
                     EVNEVTIFRTFGSKKDLFRQVAREMLPIRHIKVGVDFLLEGSAEEVLVHNALLVLDIL
                     KENRHIFMILVGELWRHPELKEEVGLEAFEQAVDFVASLMMILIQDGRLRDVDPYVAA
                     RSWTGTVQLHFLMNYVIGAGTIDPHEEEMLLRGWADIFVNGAGRG"
     gene            4625..5992
                     /locus_tag="PKM11_04160"
     CDS             4625..5992
                     /locus_tag="PKM11_04160"
                     /inference="COORDINATES: protein motif:HMM:NF016338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47733.1"
                     /translation="MDFAEYIRKFDTQTARYIPNRADWTPSDHAVYGPSDFFRLDPKE
                     ANDLRYKAVKYQLNRHIKSNRTYRSFCEDLKFDPESIRSAEDLDKVPVVSTDFFKTYP
                     TGKDFALWLANVYTGELPKIHIKSKDPSPDDVISSFNAAGMAVAYSSGTSGRHTFIPR
                     DKKAFHANEYALSKGALTMFYPRWGPDMRSFLLMPNPFKTNLFAGRLGEVMYEIMKDV
                     EVALDREVNTETVRQSMLKGDTLVGKITKFVISRSTQRSVDRIVDWIGERSKDGSRIA
                     LVGVPFMLHYVLNELKERGKSYDIGDRTMILTGGGWKAHENERIPEEKFRKEIEELLG
                     VHPEHCLDMYGMVEGNGWMLQCPEGHYFHIPTNYLHPMVLDDDGNNVGYGKYGRFAFL
                     DGSMNAYPGFIVTNDKVKMLEHCPHCDRPGPVLESGITRIAGNEVRGCGEEMRKMMAS
                     DVGGE"
     gene            5994..6965
                     /locus_tag="PKM11_04165"
     CDS             5994..6965
                     /locus_tag="PKM11_04165"
                     /inference="COORDINATES: protein motif:HMM:NF013961.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase family protein"
                     /protein_id="HNX47734.1"
                     /translation="MRSLGYMKRHEFLPNTPFIKLLATGVISVLKTSAFHLSEVKKMR
                     VRPPESERYQRRQRPYDIPEYQEGMRCASRDEKYLSATLYCEPCDPRIVAMAHKLGAF
                     QVSDLEFAKRAHDLAKNQMIVEYVPFDSAGDTLERGTGTCFHLANTMVALCRAAGIKA
                     RYKVFAMNMIAVWYDKMLGADSFMQKWYNSLGYFLIEAEVQVFIDGKWMDAVVGPDDG
                     WQATMGDPLSRLGETSLENWFEAIPGTVMLRESIPYGLPILGMLMITLAPGSVERVSC
                     NVQKMSRDGYKLIEEMGGPEAYDAMVRAKCVKRPMVDIENHSQIVFD"
     gene            7118..7552
                     /locus_tag="PKM11_04170"
     CDS             7118..7552
                     /locus_tag="PKM11_04170"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47735.1"
                     /translation="MGLLDRFRRKGGSRPEEEIRRLVLQVLEVLRETEEIMDELPPEM
                     RQGARRSFDESVGESIGDCRKRLEKMDRKLLTGELKDVPRPELVGLKERMSRLDDHLI
                     RSYLAAVKLTGNRHNKKVIRASARRRADQVEELLKALEKVVG"
     gene            7636..8397
                     /locus_tag="PKM11_04175"
     CDS             7636..8397
                     /locus_tag="PKM11_04175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
                     /protein_id="HNX47736.1"
                     /translation="MRFIYFVGTAGSGKSSLIYAFQEWLTLQGLDSVIINLDPGVEHM
                     PYQPDIDIRDWVRVDDVMEEYGLGPNGAQIVAADMMAVNAKDLAESVEKFRTNYVLVD
                     TPGQIELFAFRQSSEVIMDELGKEDSCLVFLADPNLCKTPSGFVSSVMLAATVHFRFS
                     VPFIIVLSKSDLLKDEEIETISEWADSPDALYAALTDKIDTRAVLGIELFKALESIGA
                     YKKVVAASATEPSGLEDIYAMVQESFEGGEDLSND"
     gene            8428..8601
                     /locus_tag="PKM11_04180"
     CDS             8428..8601
                     /locus_tag="PKM11_04180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47737.1"
                     /translation="MKTWVATCPDCGSIDVIYETGMVLGQKYRCLSCGYMGSFILEKE
                     IEVGKEVSGEHDA"
     gene            complement(8581..9789)
                     /locus_tag="PKM11_04185"
     CDS             complement(8581..9789)
                     /locus_tag="PKM11_04185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome-activating nucleotidase"
                     /protein_id="HNX47738.1"
                     /translation="MDEELDQSISNEIVEKLELMERQNSELLEEVRRVEGEKRYVESE
                     LFRLQKEIKRMRSELERLKSPPLIIGSIKDILIDGRVIVKSSTGPDFIVTTSEYVPSE
                     DLIVGARVALNKQTLAVMSVLPQSLDPIVTGAEIIDKPTITYDMIGGLDEQILEVREA
                     VEDPLLRPDLYRRVGIEPPKGVLLVGPPGTGKTLIAKAVANNTNATFIRFVGSELVQK
                     YIGEGARLVRELFELAREKAPSIIFIDELDSVGAKRLDVATSGDREVQRTLMQLLAEL
                     DGFNPLDNIKIIGATNRPDILDDALLRPGRFDRIIEVPVPSYEARLEIFRIHTGKMSV
                     DEGLNIESLATKTELATGADIKSICTEAGMFAIRDNRDSVSMADFERAIVKVLDNETS
                     KCTESGVMFA"
     gene            10114..11940
                     /locus_tag="PKM11_04190"
     CDS             10114..11940
                     /locus_tag="PKM11_04190"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX47739.1"
                     /translation="MDELTRFLLDMVYLLLIAGGCSIIFSKLRMPAITGYLAAGLILG
                     PTMLREVSVQESTIFLLSNLGIVLLMFYIGMELNFKRLRKTGPFIFAAMTIQMVLMVI
                     IGYLSGLAIGLDHVTSIFLGAIISGTSTAVVVAVLKDRKLLDPEVAETVIIFTVLEDI
                     GQVFILTLAAPLLVGDTPALGSTVLMVVGIVVFFGLSIIIGSALVPRVLEAISRKFPS
                     EVLIIVAIGMCFAMALLSNFIGLSIAIGAFLMGTLVSQSSVASTVKSKVEPMKDVFMA
                     VFFIDVGIRVVPAEIFSNIWLVLAIVVVFMGSKIVAVSTSCFISGRSGRTSLIIALSL
                     PVMGEFAFVIAKMALDAEVVAPSFYAAVIGAALATMLLMPPISKKADEISDLAVRVSP
                     KRFSRLLRRFEDFRCNVIAWSSRSIVAAKSIKQELTMFLIDLTTLGIVLVLFQVLGFY
                     HGTPFFHGDGTDVMAQWAIFGVSLGIILPVVVNMVRGIRRLSKTLAFGDDWAGVNTGL
                     YKAFRNMGSMILVLILLILFLPFIPSTDELSTQVWISFLGILVLSLVLARTSYRNAHE
                     RIKQALASKNISTNEVCPFGTSEGAPKGTDAPEDRSKGRGPE"
     gene            complement(11972..12697)
                     /locus_tag="PKM11_04195"
     CDS             complement(11972..12697)
                     /locus_tag="PKM11_04195"
                     /inference="COORDINATES: protein motif:HMM:NF012455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HNX47740.1"
                     /translation="MKTLKQKFTAELIGTMFLVIVAIASTILPMTIGVDMGVTVFVNA
                     VAVAFVLFALIECMAPISGAHFNPAVTLVLSRTGEMRKGDAPYYIIAQFLGAFLGLLT
                     VHLMFWDTNPVLLTVSENDMSLSQFFAEIVGTFILVGVIYGCVRGKSNATGMAVAFLV
                     GGMLVSTVSTMFANPAVTFARMMTYAICGIAPLSGIVFMVMEVIGASLAMVVFAKVLY
                     PSRLERAEKCEPGYCPPKVIEIK"
     gene            12802..13881
                     /locus_tag="PKM11_04200"
     CDS             12802..13881
                     /locus_tag="PKM11_04200"
                     /inference="COORDINATES: protein motif:HMM:NF014542.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HNX47741.1"
                     /translation="MSISEMKVRMVIIGGFLGAGKTTLITKLAKELISSKVNVGLIMN
                     DQADSLVDTQYSRALGIDSCEVSGGCFCCRFPDFMKNAEKLIDTSRPQMVIAEPVGSC
                     TDLLATVVIPLKTIYSERFEVAPLMIMVDAARVISEGFDTNGLNGYLRHHQVSEAEVI
                     IISKSDLVSPEQLERVRSAIDIINPSIRKVIYSSITGEGFSEIIDIVSGLQVSDRRPT
                     DIDYALYAEAEAELGWYNSTITVEMAPRTDAYDLGRRFLSSLSELYPAGDVAHAKIIL
                     TTSNTAMKMSCVQGRLGVDMAKGSRFAEGKGRFTVNARVVSSPDELRRNVLTALAKVF
                     PGELDFETEECFSPSPPKPFHRMKD"
     gene            13933..14424
                     /locus_tag="PKM11_04205"
     CDS             13933..14424
                     /locus_tag="PKM11_04205"
                     /inference="COORDINATES: protein motif:HMM:TIGR00270.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein bridging factor aMBF1"
                     /protein_id="HNX47742.1"
                     /translation="MICEMCGKEMASLLPVRIEGTILSVCRDCARFGDNVKAGGKPGT
                     SAEPSVIQARLENRERRMKTKDVYEGGEESFELAVDFPKRIKDAREKMGWKQDELAAK
                     MNERVSIIHKLESGTMNPDDALIRKVEKTLDIKIKEKVTIAAVEKSTGKKGMTLEDFI
                     KKK"
     gene            complement(14428..14979)
                     /locus_tag="PKM11_04210"
     CDS             complement(14428..14979)
                     /locus_tag="PKM11_04210"
                     /inference="COORDINATES: protein motif:HMM:NF021513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2240 family protein"
                     /protein_id="HNX47743.1"
                     /translation="MSELQKTVTVVFNRKGKKLLSEREFINALFFELKWADPSGAGRI
                     EAKEAQRILEAAMRQGLLELSDGYVKPTFDLKSVEVPLNYKPTKDLLKEMGEGGSAPA
                     DAIPASPKGEKKAEPMPVFSVLIDDIAAKSGWNKRDVVSRINKVVERLSVDAEVAALL
                     IGKDVGVDVRKYLLEVKEEILKK"
     gene            15220..16854
                     /gene="thsB"
                     /locus_tag="PKM11_04215"
     CDS             15220..16854
                     /gene="thsB"
                     /locus_tag="PKM11_04215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thermosome subunit beta"
                     /protein_id="HNX47744.1"
                     /translation="MSMGNQPIFILKEGSKREKGKDAQYNNIMAARAIADAVRSTLGP
                     RGMDKMLVDSMGDVVITNDGVTILKEIDVEHPAAKMLVEVAKTQDEECGDGTTTAVIL
                     TGELLKKSIDLIDANVHPTIITAGYRMAANKAMEVLDSVAVKVEPKDRETLMKIAKTA
                     MMSKSISGSKDLMAAVSVDSISSVAEKVNGKWQVDMDNIQVTKKHGGSMDDTQLIPGI
                     IVDKEPVHPAMPKRIEKAKIALLDVALEIKKTEIDAKIEISDPTQMHAFLDEEERMLK
                     QMVEAIKKVGANVVFCQKGIDDLVQHFLAKEKIYAGRRVKKGDMEKLSKATGATIISK
                     ISELDAADLGKADLVEVRKIQDEEMTFVTGCKNPKAMSILIRGGTDHVIAEIERSLDD
                     AMSVVAVAIEDGRMLTGGGSTAVEVALRLREFSSSVGGREQIAIDAYASALEVIPTAL
                     AENAGLDPIDLLIEMRKSHKAGKKHAGVNVFTGQVEDMLANDVVEPFRVGKQAISSAT
                     DAAVMILRIDDVIASRGTPGMNSKDMVGKDGLGDTD"
     gene            17008..17472
                     /locus_tag="PKM11_04220"
     CDS             17008..17472
                     /locus_tag="PKM11_04220"
                     /inference="COORDINATES: protein motif:HMM:NF013212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0051087 - chaperone binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HNX47745.1"
                     /translation="MTRIKAELEEAKAQAERNLELAKRIQADFDNYKKRAQREKEEQI
                     KAANDRLLYDLLGFLDDFERALAAKATPEEFRTGVASVHANLRSLLQSKGLVETPCEV
                     FDPALHEALCVGEGEEGKVLEVYQKGYCLGPRIVRYAKVKVGSGSNRGESDG"
     gene            17465..19306
                     /gene="dnaK"
                     /locus_tag="PKM11_04225"
     CDS             17465..19306
                     /gene="dnaK"
                     /locus_tag="PKM11_04225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HNX47746.1"
                     /translation="MAKIIGIDLGTSNSAAAVMEGGRPTIIPSAEGTSIGGKAFPSYV
                     AFTKDNQLLVGEPARRQAVTNPEGTIAAIKRKMGTDYKVTVLGKEYSPQQISAFILQK
                     IKRDAEAYLNEEVTKAVITVPAYFNDNQRQATKDAGAIAGLEVIRIINEPTSAALAFG
                     LDKVGTSQKVMVFDLGGGTLDVTIMDFSDGVFEVVSTSGDTQLGGTDMDELLIRYAVG
                     NFQKETGIDLTADKMAMWRVREACEKAKIELSTTMSTEVNLPFIAAGADGPKHLAFNL
                     TRAKLEELVEPVVNRCRGPVERAMKDSNLSADKINAVILVGGPTRMPVIQRFVETVVG
                     KKIQRGVDPMECVAMGAAVQAAVLSGEVKDVLLLDVTPLSLGIETLGGIATKLIERNT
                     TIPTRKSQIFSTAADGQTSVEIHVSQGERPMAKDNTSLGRFMLMGIPPAPRGVPQIEV
                     AFDIDANGIVNVSAKDLGTGKEAKITITASTKLSSEEIDKMVKEAERFAEDDLKNKEK
                     VEIINQADQLTYATEKALSELGEQASNEERTKVEALINDVREEIKKGDAAAIKAKTEA
                     LQKEFYAISTRIYQNMAQKQQTEGPQQGSAPKDDNVVDADYKIVDDQ"
     gene            19315..20439
                     /gene="dnaJ"
                     /locus_tag="PKM11_04230"
     CDS             19315..20439
                     /gene="dnaJ"
                     /locus_tag="PKM11_04230"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: protein motif:HMM:NF008035.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HNX47747.1"
                     /translation="MAEKRDYYEVLGVDRQAGEEEVKKAYRQLARQYHPDVSKEDPKV
                     AEERFKEISEAYEVLMDKPKRELYDKYGHAGVNSQFQGGGFNWNDFTHQGDIRDIFGD
                     GGFGGGNIFDMFFGGGRSRGPHQGQSLRYDLDITLEEAAAGLKKELTLPLTVKCDVCA
                     GTGSKSRKEEICPQCNGKGQVQRVERRGYSQFISVGACPKCGGSGKDIKDPCPDCDGG
                     WTRKRQKISLDIPKGVDTGMRLRVAGAGEPSPDGGPPGDLFVVVNVKEHKLFQRDGSD
                     LYATQEINFQEAALGATLEVPTLEGKMAEVNIPAGTQPGEVQRLKGLGMPRMEGYGKG
                     DLYIRLKLVVPKKLTAEQKELLRKFDGGDGSKKKLFGRSK"
     gene            complement(20443..20718)
                     /locus_tag="PKM11_04235"
     CDS             complement(20443..20718)
                     /locus_tag="PKM11_04235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HNX47748.1"
                     /translation="MDLLSVTFLALAGLYVLINLVALAMYGYDKMMARKGDRRISEKT
                     LLLVALLGPFGALAGMRWFRHKTRKMKFKLVPLFAVLHVLIAFLLLY"
     gene            20840..22114
                     /locus_tag="PKM11_04240"
     CDS             20840..22114
                     /locus_tag="PKM11_04240"
                     /inference="COORDINATES: protein motif:HMM:NF024241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47749.1"
                     /translation="MAIRLPSFQSTQGFDRRVWTLFYGRIISSLGFSVVMPFLSIYLH
                     NELGISMTIVGLVLLISAVVGALGQIIGGELADIMGRRKIMIIAMAARCLMFLALAYV
                     ISGGADIFVITIMVSLSSLAGSFFEPASNALIADVVEPKKRLEAYGLLRIGGNVGWTL
                     GPLLGGLLSMVSYPFLFIISAAATGTVSIIVFLFVAESISSGARRQKLSLRDLGRLRN
                     DHRFLAFCLISIPLFIMFGQMASNYAVFSTEIIGITNAEIGYIYAVNGLMVVFMQFPI
                     SRSISHLRMTKAMAVGSLLYAIGYGIVGLTPYLGVGLPHWLFSPGFLYLALCMFIVTM
                     GEMVVSPSSMTLVAKMSPESERGRYQGMYGLVSNFGFSAGPFFGGLLFDAFTGQSIFM
                     WAGIGSFGLLAALGFLGLGRRIPESTDRIDEG"
     gene            complement(22111..22626)
                     /locus_tag="PKM11_04245"
     CDS             complement(22111..22626)
                     /locus_tag="PKM11_04245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47750.1"
                     /translation="MNGKDLSDLVRDKCVVTCRDFLKEELPDLALEHPSRYLSFLIED
                     ELRVRAAGDGLQVVDDKSPFQCVSLRSADGEPAFVVMGRNMSRERTEQALDLLRSSKA
                     RDRLLLYLFSFESLADEELISQAIMEAELMRMVRDTGIVAYFAMLDARAGMGMLARID
                     GDLRSIQYLPH"
     gene            22739..23488
                     /locus_tag="PKM11_04250"
     CDS             22739..23488
                     /locus_tag="PKM11_04250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47751.1"
                     /translation="MKVVAVVTEDFRFFYETVRLLKEKGQPFISLGFSDPMPLNVELV
                     LTTEGERKRLRGRKVIASDDPAWAVKAALVLLKGGSFNRLIVGVDPGPRPGIAILGDG
                     KLLLAETLLSPEEVAPAIRDLLSFVSSNELLLRVGHGDPTNRDRIIGSLWDITRNIEM
                     VDETSTTRHTGHPDAAAAIAHGRGELLASRPRVAPTDGEVRDIQRLSRIESGGAITIN
                     SALARQVAVGAFTLNEAIEKHKRKGVSEGDP"
     gene            complement(23471..24991)
                     /locus_tag="PKM11_04255"
     CDS             complement(23471..24991)
                     /locus_tag="PKM11_04255"
                     /EC_number="2.4.2.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP phosphorylase"
                     /protein_id="HNX47752.1"
                     /translation="MKLKARYIDVDTGEVTALLHDFDCAELGLREKDRVKLSLNGKVT
                     VAIVTTSDTVIKKGEIGLMGSSQETMQSKDGDLVEVSAASKPESVEYIKKKMNGQELT
                     TEEITSIIADISSRALSNIELSAYVTSLYINGMNMRETVDLTKAMVAGGEIINFSNGP
                     IYDHHSIGGCPGNKITLLIVPIMAAAGCKMPKTSSRAISSAAGTSDIVETFANVALTP
                     AQLKEITERVGGVLAWGGSLNLAPADDLIIKAEYPLGIDPHAQLLASVMAKKKAVGAN
                     YLVIDIPMGEGTKVHTMEEAKGYARDFIQLGEELDIRVECAITYGGQPLGRAIGPALE
                     SIEAISILEGAKGPNSVIEKTLSMCGMLFEMGGEYQGVEKAKQILESGKALKKFQEIV
                     EAQGGKPGITSKDIKVGQYSVDVIAKQSGYVGHILNKSLVRVARTAGSPKDKGAGLLL
                     NKKGGNKVDKGETLFTIYSEHEWKLQEALKLAIRLEPVQIQGMILARVPAFSRVAL"
     gene            complement(24988..>25635)
                     /locus_tag="PKM11_04260"
     CDS             complement(24988..>25635)
                     /locus_tag="PKM11_04260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RuBisCO large subunit C-terminal-like
                     domain-containing protein"
                     /protein_id="HNX47753.1"
                     /translation="EAIDRVKSETGHVMMHAINVSTNGHQILEVAERAQSLGATELMV
                     DVLTCGFGAIQVLAEDPSIKLPIHVHRTMHGAMTRNLDHGINMKVFATLSRMVGGDAL
                     HVGTFGVGKMKGAAHEDLANRDMCLTKELPYKRVMPVASGGVHPGMIKKFVEIAGTEL
                     QIQAGGGVSGHPGGVRGGARAMVQAVDAAAANIPLDVYAKDHAELAAAIKKWGLA"
     assembly_gap    25636..25735
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<25736..26004)
                     /locus_tag="PKM11_04265"
     CDS             complement(<25736..26004)
                     /locus_tag="PKM11_04265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose 1,5-bisphosphate carboxylase large
                     subunit"
                     /protein_id="HNX47754.1"
                     /translation="MEYEERYLHLDAPIDIDSHVICKYKVGTDLKMTTAAAAIATEQS
                     TGTWTKLSTLNEDNFLKRSGKVTKIEGNMATIAFPVEDFSLDIGGV"
     gene            complement(26009..26935)
                     /locus_tag="PKM11_04270"
     CDS             complement(26009..26935)
                     /locus_tag="PKM11_04270"
                     /EC_number="5.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0046033 - AMP metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphate isomerase"
                     /protein_id="HNX47755.1"
                     /translation="MSAEDVAGRIRSMEIRGAAEIARRAAAAIKEEAEAYQGNDLREL
                     RSRVERSRDILIASRPTAISLWNGVQFVFKDTSQLTTAEDYRNMVVKNADHFVKRSKN
                     ALKTIGKLGANRINDGDKVLTHCNSKAAIGVMAEAWAQGKRFEAFCTESRPWRQGVLT
                     ANDLAKLGIPVTMIIDSAVRYVMKDMDLVLVGADTIASNGALINKIGTSQVALAAHEA
                     RVPFMVCAETFKFSPRTIYGEMVKIEERDATEVVKPGEVPPEVKVFNPVFDATPPEYI
                     DAIITEIGVIPPYAAYQVIVKELGYEFMFNED"
     gene            complement(26982..28697)
                     /gene="polX"
                     /locus_tag="PKM11_04275"
     CDS             complement(26982..28697)
                     /gene="polX"
                     /locus_tag="PKM11_04275"
                     /inference="COORDINATES: protein motif:HMM:NF006375.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="HNX47756.1"
                     /translation="MDNNAKVASVLEEVADLLELKEDTFFQVRAYRRVAKEISSLTED
                     IKDLYVRGHLDQVPGVGKAINDKIVEILRTGELQYLIDLRNEFPAGLLQVMQVPDVGP
                     KTAGRLYKELKVTNLQDLKAAAEQHRIRTLKGFGERTEENILKGIRYLESRQGRMLLG
                     YAYPRGRALEEHLRERGFELVSLGGSLRRMKETIGDIDILVGSSEAERAMETFVSFPQ
                     TAEVMLRGATKTSIRLQDGVQVDMRVVDPSSFGAALQYFTGSKEHNVKVRSLANDLGY
                     KLNEYGVFRLSDGSKVAGETEEGVYELLGLQWMPPEMREDRGEVDLARKGQVPRVVTL
                     SDICGDLHTHSEASDGVDSVEAMARAAEAHGYEYLAITDHSHSLTIGNGLSAERLLES
                     MEHVRKVNEAHPDLHLLIGTEVEIDEKGGLDYPPKLLEDLDIVVAAVHSRFKMTPAEM
                     TERLVTAVSNENVNILAHPTGRIIGEREGYSYDMDKVMQAAKDHGVAMEVNSFPERLD
                     MNDVHCAMARERGVTISIDTDAHNVRQLDYILYGVATAKRGWVPPELVLNALPWDQLR
                     KRLGL"
     gene            complement(28706..29251)
                     /locus_tag="PKM11_04280"
     CDS             complement(28706..29251)
                     /locus_tag="PKM11_04280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47757.1"
                     /translation="MPDKDNNLTSEEMESMAKEAITIWWSTVVKAVVINSNSPEMKKI
                     LHTFLASAVTEMVRSQGPKRTLDLMGPIMRTGGKKAAVRALEEHEIVDRDGIAISSLI
                     DLWEGALGVRGEIVEKSEIAVIKVAKQCPFANQPPELCSLFGKFVDGFCEVINPEYGW
                     CQTHRMSDGDKECRWVCKKED"
     gene            29418..29696
                     /gene="albA"
                     /locus_tag="PKM11_04285"
     CDS             29418..29696
                     /gene="albA"
                     /locus_tag="PKM11_04285"
                     /inference="COORDINATES: protein motif:HMM:TIGR00285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006325 - chromatin organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein Alba"
                     /protein_id="HNX47758.1"
                     /translation="MFEGNVMFIGNKPIMSYVLTAVPKLQELGELTIKARGMSISKAV
                     DVALILQDRYIKECHVDGIDIRTEVLDGDNGEKVNVSSIQVHLRSPVP"
     gene            29785..30060
                     /locus_tag="PKM11_04290"
     CDS             29785..30060
                     /locus_tag="PKM11_04290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176109.1"
                     /note="Sso10b; forms dimers; interacts with silencing
                     protein Sir2 which regulates Alba by deacetylation of a
                     lysine residue which affects DNA binding affinity; binds
                     double-stranded DNA tightly distributed uniformly and
                     abundantly on the chromosome; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HNX47759.1"
                     /translation="MSELNAIYIGQKPMMNYVLAAGKRLVGNGSSVLIQARGRSISKA
                     VDVALITLDRAKGEIKLGEILISTEVLPGADGNPLNVSCIKIILSRA"
     gene            complement(30057..30764)
                     /locus_tag="PKM11_04295"
     CDS             complement(30057..30764)
                     /locus_tag="PKM11_04295"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX47760.1"
                     /translation="MNREYAEGYLKGYEEGMREALDELIAMTCRKSYTSTEIQILAKN
                     QRNSIPKKKASKKSELEHALGSSLDAIEEKPDEPGREAAPGKTLLIKGEGNQQALADF
                     RDLVRAGWDGLCISRASPKEVKEFVGKECTVLWLTKADPMGGDQDREEYILPTETAKM
                     QTIIRNFLNKNKGRPSVILLDGMTYIVTNTDFRSFLKIAQKLKDDVNQARSLLLLPYE
                     PKNLPESEVNLLINEMS"
     gene            30855..>31894
                     /locus_tag="PKM11_04300"
     CDS             30855..>31894
                     /locus_tag="PKM11_04300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47761.1"
                     /translation="MGSRARFRGIKKTPKNMEREMLATSQRLSDDPSLVVPKLLDEVR
                     KSPFAYLEKMLSKVQDHRDDAEKLIKMAGKGDQFVRAYAAAVSLSASGKLPYLTTATL
                     PVGPVSFAMRGTVDREKLIALQHFDDPDLRLLAYWDMAREDRLHIYSTEKGLYASVSG
                     PKAPEEYVKEMLENLPYRTIENDCGHDRPAVRVKWISANKEVRVCAECASDVNTAQHL
                     MARVAAPDPYDDIKVSVEHRYGGGRPECSGDFSTPPALIKRYIDGELDDSGLIAEHIK
                     AKGEWMRSRGQVYIIGQECFGKDGEAFLNALKGNEQEKVALRSVLALNVPIVSDQNQA
                     GKVISELWDPHA"
BASE COUNT         6424 a         9638 c         9484 g         6248 t
ORIGIN      
        1 agcctggcgg tcatcggcca gacggtcatc gccggcgtct ggtcggcggc attgatggtg
       61 ccggccggac tggccatgtc ctccctcact aaaaagaaga cctacgccgc ggtgggcacc
      121 ttcatgttct tcttcggcat gatgatcgtg tccgggatat tcagcgacat agcccgggac
      181 tggttccttc tggacccttc ccaggtgctg taccagaccc acaccgtgat ctacggtctg
      241 gaactggatg acatcgtcaa ccgttatcta ctggccgcca tggccttcct gctcaccgtt
      301 ccgccggtgg ctctcgttta ctatcgcata atgcgcatgg aggcgggtaa atgagcaacg
      361 tggtggaggc gcgcctcctg tccaagtggt acggggaggt catcggactg aacaacttca
      421 gcatcgacgt ccccaaaggc ataactggca tcgtcgggcc gaacggggcc ggcaagagca
      481 ccttctttaa gttgctgaca ggcaacatca agaccaacgt ggggcacctg cgggtgctgg
      541 gcgaggaacc ctggcagaac cctgccttgc ttgccaagat aggcttctgc cccgattacg
      601 atttcctgcc gccggacctc aagggccggg aatatctgcg cttcgtggcc gggctgcacg
      661 ggatggacgg cgctcgaaag gcgacgcgag tgaacgacgt gctgggcata gtcagcatga
      721 ccaaggacgc cgaccgggtc atgggcggct attccaaggg catgaggcag cgcatcaaga
      781 tcgccggggc gcttctgcac gagccgcagc tgcttctgct ggacgaaccg ctcaccggga
      841 ccgatcccct gatccgcaag gagataatcg acctggtcaa ggacctcaac aaagtgcatg
      901 ggcatgacgt catcgtatcg tcgcacgtgc tgcacgagat cgagaggatg acccaccagg
      961 tggctctgat atacaagggt cggtcggtgg ccagcgggga catctccgag atacgccagc
     1021 tgatgagcga ccacccgcac aacatcgtgc tggaggggcg cggtctagtg ccgttggcgc
     1081 aggcgctgct caccaaaccg tacacctcct cgatcgaact gcgcgccgac cgcctgggca
     1141 tgtacgtccg ggtggaccgg ccggaggagt tcttcgattc cctgccggaa ctggtggcgg
     1201 gaacgggatg cgagctggaa cgagtggaaa gcctggatga tgacctggaa tcggtgttcc
     1261 ggtatctggt ggggtgatga acatgtcctt caatttcatc ggtcttcgca cggtggcggc
     1321 cttctccgcc cgcaagctgc tcatgaaccg gcgatggatg acggtcgcgc tgctcggggc
     1381 cctggtcgcc ctggtcatgg gctacgcggc gacgcaggac ggggtcaaca tggactccgc
     1441 cagcgagctg atggtcttgc tgctgctggc gttccttctt ccggtgctct ccctgatcta
     1501 cggggcgtcc atgatccgga acgagatgga cgaccggagc atcgtgcagg tgatcaccgc
     1561 gccgctggac cgcaggatat cctatctggg atactacata gggctggtgg tggtgctgtg
     1621 cctcctgatc acggtcgtga ccgtcatcgg cggagcggcg ttccttatct tctccccggt
     1681 gagggatggc gggctgcagc tgatcgtcac cttcatcgcc ctgcaatatc tgggagtgat
     1741 ggtctattcc gccctgttcc tgttcctggg gacgctgatg aagcagccga tatacctggg
     1801 actgatctac atcttcgtct gggagggctt cgtggcctcc attcccggct ccatcggcaa
     1861 ggtgaccatc cgccatcagc tacaggttat cggcaacgag ctcaccgatt acggttcctg
     1921 gaccaacggg gactgggcag tgtccatact ggccctggtg ctggtgaccg cgttactggt
     1981 gctggccgga gcctacgtgc tccggcagga agaggtctcc tgatcggcgg ccgagcgagc
     2041 tccgaacgtt gaaaaaactt tttcaccgcc taggtgaacc atggccggga gggggtacag
     2101 ggacgggggg ctggtcatca gttccaagtg cggataccgc ggaatggctt atggaagagg
     2161 gcgatcgacc cgtaagatat ccggtccttc gcgatctcca gaagatgagg gtcagagctt
     2221 tcggcagatc ttccggcggg cctcgagaaa gatcatcaga gatccgatca ccaggaaggc
     2281 caggaagatg agcaggaccg ccgggctgtc aacggtcatt attcccagtc ccatcatgac
     2341 caccgagacg agaagcccga ggaacaccag ctccctggtg gggtccgtct ccttcaattc
     2401 gcacgaacct ccatgtatcc atttggcgac cgtcgccgcg gtcaggtcgg ccatgagagc
     2461 gccgacgaat atgaccagaa gtccgatgac cacccgaatg gcgtagttct cgaccagcgt
     2521 acctccgtca ccgaagaggc cgctgtcgat cagaacatcg atggcgaata cggcagcgat
     2581 ggcgaacacc agcgccttgg cgatcttgcc agctactatc gagaccttcg aaccggagat
     2641 gccaacggtc cggtcccgcc cgaaatggca gcagacctcc cggaccagct ccccggccac
     2701 ataggctagg atgaacccta ttatcagcgt cgctatggcg attatgacgt tcggtaccgt
     2761 gtccagcaat attcccaacc aagcaccgaa ctctacgggg acgtccgcca agatcaatcc
     2821 tcttctctta agttgtcgct cgagcttata atggtgcttc ttcggcaccc agaaaaatgg
     2881 gagaaaggat aaaagggggc agcgccccgt tcacggcttg gccatcttct tggtcatggc
     2941 gaaggccacc gggaccagca tcaacgccat ggcgatggcg aaggcccagg atatgttggc
     3001 tattatgccg gtgacgcccg ggaaggtggc gaagatggcg ccggtgccga tgatcaggaa
     3061 gatcgcgtac agcacgaact tggcgtagcc ggcgacctcc ttgaaatcgg ggtgctcgtc
     3121 cgcgacggac ttgattaggg cgtccgtcag cagtattccc actccgatga tcacgaagcc
     3181 caggaccagg gtgtacacca gggcgccggt gagcagcatc acgttcagag ccagcagcac
     3241 cacgaaggcg atgaggccga tgaacagcag gttcttcagc atctcggcga tgttctgctt
     3301 gccctccggg aacatgggcc gcacgatgcg gccgatgaag gaggacagga aatcagcgaa
     3361 gaacgctccc aggaccagca ccagaacgcc cacgaacacc ttgggcaggt agttcgccag
     3421 accggtgagg taatccccga agatcccgct catgtccagg acctggatgg acagaacgat
     3481 gaagaagatc atgacgaagg ccatcaccag catgctggcc aggttggagg cgtataatcc
     3541 tgacgacagg aacgcccggc cggtggcggt ctggttgaag aacctctcca gaccgacctt
     3601 ccgcaccacc atcttgatta tctttcccgc tacccaggcc accaagaggc ctatgatcag
     3661 aacgatgatg gccgccagga tggccggtac cgccaacagg aagtcgtccc acatcgtgct
     3721 cagttcatct acaaggtcaa ccaatttttc accttaccat cccttttaat ttatatttta
     3781 taattaactt tccatccgcg ttgaatctgg attatcaaaa atgatagaat attatcctga
     3841 atgttttcat tgatcgttcc tcatcccctc cccgccccgt tgacgaatat gtccgcccag
     3901 cctctcagca gcatctcctc ctcgtgcggg tcgatggtgc ccgcccctat gacgtagttc
     3961 attaggaaat gcaactgcac cgtgccggtc caggagcggg ccgccacgta ggggtccacg
     4021 tcccgcagac gcccgtcctg gatcaagatc atcatcagcg aggcgacgaa gtccactgcc
     4081 tgctcgaagg cctccaggcc cacctcctcc ttcagctccg ggtgcctcca cagctccccc
     4141 accagtatca tgaagatgtg gcgattttcc ttcaggatgt caagcaccag gagggcgtta
     4201 tgcaccagca cctcctcggc gctgccttct aaaaggaagt ccaccccgac cttgatgtga
     4261 cggatgggga gcatttccct ggccacctgg cggaagaggt ccttcttgct gccgaacgta
     4321 cggaagatgg tcacctcgtt cacttccgcc ctctcagcga tggaccttgt cgtcgttccg
     4381 tcaaaaccct tctccgcgaa gagcgcgaag gccgcggcca atatcctctc ctttgcgctc
     4441 tccatctctt ccgggagaat ttccttcgta acggtcatca atatagcaag taattacttg
     4501 catacatata tgtacgccta aacccaggat ctacgagcat cgaaaaaaat actgcgatcg
     4561 tcgattttca accatcaagg aaataaacat aatcttttta atagggttgc cgttgggaac
     4621 ctaaatggac ttcgccgagt atatccgcaa gttcgatacc caaaccgcca ggtacatacc
     4681 aaatcgggcg gattggacgc catcggatca cgccgtatac ggaccatcgg actttttccg
     4741 actggacccc aaggaggcga acgatctccg ctacaaggcg gtgaagtacc agctgaaccg
     4801 gcatatcaag agcaaccgga cctaccgcag cttctgcgag gacctgaagt tcgatcccga
     4861 gtcgataagg tccgcagagg acctggacaa ggtcccggtg gtctccaccg acttcttcaa
     4921 gacctatccc acggggaagg acttcgccct ctggttggcc aacgtgtaca ccggggagct
     4981 tcccaagata cacatcaaga gcaaggaccc ttcacctgac gacgtcatca gctccttcaa
     5041 cgccgctggc atggccgtgg cctacagcag cggcacctcc gggcgacaca ccttcattcc
     5101 gagggacaag aaggccttcc acgccaatga gtacgctctg tccaagggcg ccctgaccat
     5161 gttctacccc cgctgggggc cggacatgcg cagcttcctg ctgatgccca accccttcaa
     5221 gaccaatctg ttcgcgggga ggctgggcga ggtgatgtac gagatcatga aggatgtcga
     5281 ggtggctctg gaccgcgaag tgaacaccga gaccgttcgc caatccatgc tcaaggggga
     5341 caccctggtc ggcaagatca ccaagttcgt gatcagccgc agcacccaga gatcggtgga
     5401 ccgcatagtg gactggatag gggagaggtc caaggacggc tcccgcatcg ccctggtcgg
     5461 cgttccgttc atgctgcatt acgttctcaa cgagctcaag gagaggggca agtcatacga
     5521 catcggcgac cggaccatga tcctcaccgg aggcggttgg aaggctcacg agaacgaacg
     5581 gatccccgag gagaagttcc gcaaggagat cgaggagctt ctgggcgtcc atccggagca
     5641 ctgcctggac atgtacggca tggtggaagg caacggctgg atgctgcagt gtccggaggg
     5701 gcattacttc cacattccta ccaactatct gcaccccatg gtgctggacg acgacggcaa
     5761 caacgtcgga tacggcaaat acggccgctt cgccttcctg gatggctcca tgaacgccta
     5821 tcccggcttc atagtcacca acgacaaggt caagatgctg gagcactgcc cgcactgcga
     5881 ccgtcccggt ccggtgctgg aatccggcat cacccgcata gccgggaatg aggtacgggg
     5941 ctgcggcgag gagatgcgaa agatgatggc ctctgacgta ggaggggagt gatttgcgct
     6001 cgctaggtta catgaagagg catgagttcc tgcccaacac ccctttcatc aagctgctgg
     6061 ccaccggcgt gatctccgtg ctcaagacca gcgccttcca cctttccgag gtcaagaaga
     6121 tgagggtgcg gccgccggaa tcggagcggt atcagcggcg ccaacgtccg tacgacattc
     6181 cggagtacca ggagggcatg cgttgcgcct cccgtgacga aaagtacctt tccgccactc
     6241 tatactgcga gccgtgcgac cctcgcatcg tggccatggc ccacaagctg ggggccttcc
     6301 aggtatccga tctggagttc gccaagcgcg ctcacgacct ggccaagaac cagatgatcg
     6361 tggagtacgt tccgttcgac tccgccggcg acacgctgga aagaggaacc ggaacctgct
     6421 tccatctggc caacaccatg gtggccctgt gccgcgcggc tggaattaaa gcaaggtaca
     6481 aggtgttcgc catgaacatg atcgccgtct ggtacgacaa gatgctgggc gcggacagct
     6541 tcatgcagaa gtggtataac tctctcggtt acttcctcat cgaggccgag gtgcaggtgt
     6601 tcatcgacgg caaatggatg gacgcggtgg tcggtccgga cgacggatgg caggctacca
     6661 tgggcgatcc cctgagcagg ctcggggaga cctccctgga gaactggttc gaggccattc
     6721 cgggaacggt catgctccgg gagtccattc cttacgggct gccgatactc ggtatgttga
     6781 tgatcacctt ggcccccggt tccgtggaaa gggtgagctg caacgtgcag aagatgtccc
     6841 gggacggcta caagctcatc gaggaaatgg gcggccccga ggcctacgat gccatggtca
     6901 gggccaagtg cgtcaagagg ccgatggtcg acatagagaa ccactcccag atagtgttcg
     6961 actgaggttc tctccttccg atccgtccga tgggtaggtc gtctgttttc caccgttcca
     7021 tgtcgtttcg tggataaccc cgggggcgac cggaccatcg cgccactccg atgaacgcca
     7081 tgtttttatt ccgcgctatc gcatgacctt cctgtctatg gggcttctag atcggttcag
     7141 aaggaagggc ggctcgcgtc ctgaggagga gatcaggcgc ctggtgctcc aggtgctgga
     7201 ggtcctgcgg gagaccgagg agataatgga cgagctcccg cccgaaatgc gtcagggggc
     7261 ccgccgctcc ttcgatgaga gcgtcggtga gtccatcggg gactgccgca aacggctgga
     7321 aaagatggac cgcaagctgc tgaccggaga gctgaaggac gttccgaggc cggagctggt
     7381 cgggctcaag gagcgcatgt cacgcttgga tgaccatctg atccgttcgt atctagcggc
     7441 cgttaagctc accggcaacc ggcacaataa aaaggtcatc cgggcctcgg ccagaaggcg
     7501 tgccgatcag gtcgaggagc tgctgaaggc tctggaaaag gtcgttggct gatccgctgg
     7561 tcgaataacg gtcgtccggc atcccgtggc gtcgcaagta tcataagggc gtcttacttc
     7621 ctttcgaggg atatcatgcg tttcatctac ttcgtcggca ccgccgggag cggaaaaagt
     7681 tctctcatct acgctttcca ggaatggcta accctgcagg gactggactc ggtcatcatc
     7741 aacctcgatc cgggcgtgga gcacatgccc taccagccgg acatcgatat ccgcgattgg
     7801 gtgcgggtgg acgacgtaat ggaggagtac ggtctgggac cgaacggcgc gcagatcgtg
     7861 gccgcggaca tgatggcggt caacgccaag gaccttgccg agtcggtgga gaagttccgc
     7921 accaactacg ttctggtcga tacgccagga cagatcgagc tgttcgcctt ccggcagagc
     7981 agcgaggtca tcatggatga actgggaaag gaggattcct gcctggtgtt cctggccgac
     8041 cccaatctgt gcaagacgcc ctccggcttc gtttcatcgg tcatgctggc ggccaccgtg
     8101 cacttccgtt tctccgtacc gttcatcatc gttctatcca agagcgacct cttgaaggac
     8161 gaggagatcg agaccatcag cgaatgggcc gattcgccgg acgccctgta cgcggcgcta
     8221 acggacaaga tcgacacccg cgccgtgctg ggcatcgagc tgttcaaggc cctggagtcg
     8281 atcggcgcct acaagaaggt ggtcgcggcg tccgccacgg aaccgtcggg cctggaggac
     8341 atctacgcca tggtgcagga gtccttcgag ggcggcgagg acctctcgaa cgattgattt
     8401 aagttcggag aggccggtca ttacatcatg aagacctggg tggccacctg ccccgactgc
     8461 ggttccatcg atgtgatata cgaaacggga atggtcctgg gtcagaagta ccgctgcctg
     8521 agctgcggtt acatggggtc cttcatcctg gaaaaggaaa tagaagttgg gaaagaggtt
     8581 tcaggcgaac atgacgcctg actcggtgca cttggacgtt tcgttgtcca gcaccttgac
     8641 gatggccctc tcgaagtcgg ccatgctcac cgagtcccgg ttgtcccgga tggcgaacat
     8701 tccagcctcg gtgcatatgg acttgatgtc cgcgccggtg gccagctcgg tcttggtggc
     8761 cagggattct atgttcagtc cttcgtccac gctcatcttg ccggtgtgga tgcggaatat
     8821 ctccaggcgg gcctcgtagc tcgggacggg cacctcgatt atgcggtcga agcgtcccgg
     8881 ccgcagcagc gcgtcgtcca ggatgtccgg gcggttggtg gcgccgatga tcttgatgtt
     8941 gtctaacggg ttgaaaccat caagttcggc cagcagctgc attaacgtac gctgaacctc
     9001 gcggtccccg gacgtggcga cgtccaggcg cttggcgccc acggaatcca gttcatcgat
     9061 gaagatgatg ctgggagctt tctcgcgggc cagctcgaac agctcccgga ccagccgggc
     9121 gccttccccg atgtacttct gtaccagctc ggaaccgacg aagcggatga aggtggcgtt
     9181 ggtgttgtta gcgaccgctt tagcgatgag cgtctttccg gtgccgggcg ggcctaccaa
     9241 tagcactccc ttcggaggct ctatgcccac gcgccggtag agatcgggac gaagcagggg
     9301 gtcctccacc gcctcgcgga cctcgagtat ctgctcgtcg aggccgccta tcatgtcgta
     9361 ggtgatggtc ggcttgtcga tgatctcggc cccggtgacg atggggtcca gggattgcgg
     9421 gagaacggac atcacggcca gggtctgctt gttgagagcg acgcgggcgc caacgatgag
     9481 gtcctccgac ggaacgtact cggaagtggt aacgatgaaa tccgggccgg tgctgctctt
     9541 gacgatcacg cggccgtcga tgaggatgtc ctttatgctg ccgatgatga ggggagggga
     9601 cttcaaacgc tccagctcgg agcgcatcct ctttatctcc ttctgcagcc ggaagagctc
     9661 gctctccaca tacctcttct caccctccac ccgtctgacc tcttcgagca gctcgctgtt
     9721 ctggcgctcc atgagctcca gcttctcgac gatctcgttg gagatggatt ggtccagctc
     9781 ttcgtccaac aaatatggca ccttcgagga ttgattaaac cgccctctat ttgagcattt
     9841 gccatattat accgatcacg cacatcgtcc gttcgttcca tctgacagga catcggttga
     9901 ctggcattgg tccccggaac ctaccagttc cggcgataat ggcggcagaa aaaatgttaa
     9961 atcagatgca acgttctggt cacccatagt tccgaccttt caaaacgacc ttggatcgat
    10021 cggaagcgcc atctccctgg gcggtacatc atcctaaaag gatcggtacc gaggagaccc
    10081 aagtggatct agaaaattgt atgaaggatg tgcatggacg aactgacccg attcctgctg
    10141 gacatggtct acctgctgct catcgcaggg ggctgctcga taatcttctc caagctgcga
    10201 atgccggcca taacaggtta tctggcagcc ggtctcatcc ttggtccgac gatgctccgc
    10261 gaggtatcgg tgcaggagag cacgatcttc ctcctctcga acctggggat cgtgctcctg
    10321 atgttctaca tcgggatgga gctgaacttc aaacgcctgc gtaagaccgg gcccttcatc
    10381 ttcgcggcga tgaccataca gatggtcctg atggtcatca tagggtacct atccggccta
    10441 gccatcggac tggaccacgt gacatccatc ttcctcggtg ccataatctc cgggaccagc
    10501 acggccgtgg tggtggccgt tctcaaggac cgcaagctcc tggaccccga ggtggccgag
    10561 accgtgatta tcttcaccgt cctcgaggac attggccaag tgttcatatt gaccttggcg
    10621 gcccctctgc tggtggggga cacccccgcc ctcggctcca ccgtcctgat ggtggtaggc
    10681 atcgtggtgt tcttcgggct cagcatcatc atcggttcgg ccttggtgcc ccgggtcttg
    10741 gaggcgatct cccggaagtt cccctccgag gtgctcatca tcgtggccat cgggatgtgc
    10801 ttcgccatgg ccctgctctc caacttcata gggctgtcca tagccatagg ggccttcctc
    10861 atgggcacgc tcgtctcgca atcgtccgtg gcctccacgg tcaagtccaa ggtggaaccg
    10921 atgaaggacg tgttcatggc cgtcttcttc attgacgtgg gcatccgggt ggttccggcc
    10981 gaaatattca gcaacatctg gttggtattg gcgatagttg tggtgttcat gggctccaag
    11041 atagtggcgg tgagcacctc gtgcttcata tcagggaggt ccggccggac cagtctgata
    11101 atcgccttga gcctgccggt gatgggggag ttcgccttcg tgattgccaa gatggccttg
    11161 gacgctgaag tggtggcgcc atccttctac gcggcggtca tcggggcggc gctggccacg
    11221 atgctactga tgcctcccat ctccaagaag gccgatgaga tctccgacct ggccgtcagg
    11281 gtcagcccga aacggttctc caggctcctt cggcggttcg aggacttccg ttgcaacgtc
    11341 atcgcctggt cctccaggtc catcgtggcg gcgaagagca tcaagcagga gctgaccatg
    11401 ttcctcatcg acctgaccac cctggggatc gtcctcgtcc tcttccaggt cctggggttc
    11461 tatcatggaa cgccgttctt ccatggcgat ggaacggatg taatggccca atgggcgatc
    11521 ttcggggtaa gcctgggcat aatccttccg gtggtggtca acatggtccg cgggatcagg
    11581 aggctgtcta agaccctggc cttcggcgat gattgggcgg gcgtgaacac cggcttgtac
    11641 aaggccttcc gcaacatggg gtccatgata ctcgtcctga tattgctgat attgttcctg
    11701 cccttcattc ccagcacgga cgagctatcc acccaggtct ggatatcttt cctggggata
    11761 ttggtcctat ccctggtcct ggcccgaacc tcctaccgga acgctcacga acggattaaa
    11821 caggcgttag ctagcaagaa catctctacc aacgaggtgt gcccgttcgg aacgtccgaa
    11881 ggggcgccga agggaacgga cgccccagaa gaccgttcga aagggcgggg tccggaatag
    11941 tgaccgttgg gggtccagac cggaccgccg ttcacttgat ctcgatcacc ttgggtgggc
    12001 agtagcctgg ttcgcacttt tccgcccttt ccagccgcga ggggtagagc accttggcga
    12061 agaccaccat ggccagcgat gctccgatga cctccatgac catgaaaacg atgccgctca
    12121 ggggcgcgat gccgcagatc gcataggtca tcatccgggc gaaggtcacc gcgggattgg
    12181 cgaacatggt gctgacggtc gagaccagca tgccgccgac cagaaaggcc acggccatcc
    12241 cggtggcgtt gctcttgccc cgaacgcagc catatatcac gcccaccaag atgaaggtcc
    12301 ccacgatctc ggcgaagaac tggctcaggg acatgtcgtt ctccgagacc gtaagaagta
    12361 cggggttggt gtcccagaac atgaggtgaa cggtgagcag tcccaggaac gctcccagga
    12421 actgagctat gatgtaatag ggcgcgtccc ccttgcgcat ctcgccggta cgggacagga
    12481 ccaaggtcac cgccggattg aaatgagctc cggagatggg ggccatgcat tctatcaggg
    12541 cgaagagcac gaaggccacc gccaccgcgt tcacgaagac ggtcacgccc atgtccaccc
    12601 ctatggtcat cggcagtatc gtgctggcta tggccacgat cactaggaac atggtgccga
    12661 tgagctcggc ggtgaacttc tgcttcaagg tcttcatttt tagcgcctta ttcccagatg
    12721 gaaatatttt gtatatattt gatttcatta tcaattaata aagtataaaa tggaggaagg
    12781 cgatccgccc gcagaaaggt gatgtccata tctgagatga aggtccgcat ggtgatcatc
    12841 ggagggttcc tgggagcggg aaagaccact ctcataacca aactggccaa ggagctgatc
    12901 tcctcgaagg tgaacgtagg gctgataatg aacgatcagg ccgactccct ggtggacacc
    12961 cagtactccc gggccctggg cattgactcc tgcgaggtct ccggcggctg cttctgctgt
    13021 cgcttcccgg acttcatgaa gaacgccgag aagctcatcg atacctcaag accgcaaatg
    13081 gtcatcgccg agccagtggg cagttgcacc gatctcctgg ctacggtggt cattccgctc
    13141 aagaccattt acagcgagag gttcgaggtc gctccgctca tgataatggt cgacgcggcc
    13201 cgggtcatat cggaaggctt cgacacgaac ggactgaacg gttatctgag gcaccatcag
    13261 gtcagcgagg ccgaggtcat catcatctcg aagtccgacc tggtctcccc ggaacagctg
    13321 gaacgagttc gctcagccat cgacatcatc aatccttcca tcagaaaggt gatctattca
    13381 tcgatcaccg gggaaggatt tagcgagata atcgacatcg tctccggcct gcaggtgagc
    13441 gaccgccggc ctacggacat cgactatgcg ttatacgcgg aggcggaggc ggaactgggc
    13501 tggtacaact cgaccataac ggtagagatg gcaccccgca ccgacgccta cgacctgggg
    13561 cggaggttcc tcagttcgct atcggaactg tacccggccg gggacgtggc gcacgccaag
    13621 ataattctca ctacctcaaa caccgccatg aagatgtcct gcgtgcaagg ccgtctaggc
    13681 gtcgacatgg ccaagggatc gaggttcgcc gagggcaagg gccggttcac ggtgaacgcc
    13741 cgggtggttt cctctcccga cgaactgcgc cggaacgtcc ttaccgccct agccaaggtg
    13801 ttcccgggag aactggattt cgagaccgag gaatgcttct ccccctcccc tcccaagccg
    13861 ttccacagga tgaaagattg agcttcggct catgtataaa ttcatcttcc tgtattaaca
    13921 cgaacgatag agatgatatg cgaaatgtgc ggtaaggaga tggcgagcct gctgccggtg
    13981 aggatagagg ggaccatcct cagcgtgtgc cgggactgcg cccgattcgg cgacaacgtg
    14041 aaggcaggtg gcaaacccgg gacctcggcc gagccgtccg tcatccaagc caggctggag
    14101 aaccgcgagc gccgcatgaa gaccaaggac gtctacgagg gcggtgagga atcgttcgag
    14161 ctggccgtgg actttcccaa gcggataaag gacgcccggg agaagatggg ctggaagcag
    14221 gacgagctgg ccgccaagat gaacgagcgg gtcagcatca tccacaagct ggaatcgggg
    14281 accatgaatc ctgacgatgc cctgatacgc aaggtggaga agaccctgga catcaagatc
    14341 aaggagaagg tcaccatcgc cgcggtggag aagtccaccg gcaagaaggg catgaccctc
    14401 gaggatttca tcaagaagaa gtgagggtca cttcttcaaa atctcttcct tcacttctaa
    14461 cagatacttc cgaacgtcca ccccgacgtc ctttccgatg agcagcgccg caacctcggc
    14521 gtccacggac aagcgctcca cgaccttgtt tatccgggag accacgtccc gcttgttcca
    14581 gccggacttg gccgcgatgt cgtctatgag aacggagaaa acaggcatcg gctcggcctt
    14641 cttctcccct ttaggcgacg cggggatcgc gtcagccggg gcggaacctc cttcgcccat
    14701 ctccttcaac aggtccttgg tgggcttgta gttgagggga acctccaccg acttgaggtc
    14761 gaaggtcggt ttcacgtaac cgtcagaaag ctccagcaac ccctggcgca tggccgcctc
    14821 caatatccgc tgcgcctcct tggcctcgat acggccggcg ccagaagggt cggcccactt
    14881 cagctcgaag aagagggcgt tgatgaactc ccgctcggag agcagcttct tgcccttgcg
    14941 gttgaaaaca acggtcaccg tcttctggag ctcgctcatt cgatcgtccc tcgaagcgcg
    15001 tcaggggata taaccttgct ccaagcccct cccgaacacg ataatatcaa atacggccca
    15061 gccctttcgc cgccctacgc ttccgccaga ggaaaatatc ttttttgtat gggtgcgagg
    15121 cggaggtaca atagcttcat atagaagaac aaacattcca atgcccacta gctcagagct
    15181 aggtgtcaag ctaatttgat accaatggag gttagcagca tgtcaatggg aaaccaaccg
    15241 atattcatac tcaaagaagg ttccaagcgc gagaagggca aggacgccca atacaacaac
    15301 atcatggccg ccagggccat cgctgacgct gtcagaagca ccctagggcc ccgcggaatg
    15361 gacaagatgc tggtcgactc catgggcgac gtcgtcatca ccaatgacgg tgtcaccatc
    15421 ttgaaggaga tcgacgtaga gcacccggcc gccaagatgc tcgtcgaggt cgccaagacc
    15481 caggacgagg aatgcggcga cgggaccact accgcggtca tcttgaccgg cgagctcttg
    15541 aagaagtcca tcgacctgat agacgctaac gttcacccga ccatcatcac cgccgggtac
    15601 cgcatggccg ccaacaaggc catggaggtc ctggactccg tcgccgttaa ggtggagccg
    15661 aaggaccgcg agaccctcat gaagatcgcc aagaccgcca tgatgagcaa gtccatatcc
    15721 ggttccaagg acctgatggc tgccgtctcc gtggactcca tcagctccgt cgctgagaag
    15781 gtcaacggca agtggcaggt ggacatggac aacatccagg tcaccaagaa gcacggcggt
    15841 tccatggacg acacccagct catccccggc atcatcgtgg acaaggagcc ggtgcacccc
    15901 gccatgccca agaggatcga gaaggccaag atcgccctgc tggacgtcgc cttggagatc
    15961 aagaagaccg agatcgacgc caagatcgag atctccgacc ccacccagat gcacgccttc
    16021 ctcgacgagg aggagcgcat gctgaagcag atggtcgagg ccatcaagaa ggtgggcgcc
    16081 aacgtggtgt tctgccagaa gggcatcgac gacctggtgc agcacttcct ggccaaggaa
    16141 aagatctacg ccggccgccg cgtcaagaag ggcgacatgg agaagctgtc caaggccacc
    16201 ggagcgacca tcatatccaa gatcagcgag ctggacgccg ctgacctcgg taaggccgac
    16261 ctggtcgagg tccgcaagat ccaggacgag gagatgacct tcgtgaccgg ttgcaagaac
    16321 cccaaggcca tgtccatcct gatccgcggc ggaaccgacc acgtgatcgc cgagatcgag
    16381 aggtccctgg acgacgccat gagcgtcgtc gccgtcgcca tcgaggacgg tcgcatgctg
    16441 accggcggag gctccaccgc tgtcgaggta gctcttcgcc tacgcgagtt ctcctcgtcc
    16501 gtcggcggac gcgagcagat cgccatagac gcctacgctt ccgcgttgga ggtaataccc
    16561 accgctctgg ccgagaacgc cggactggac cccatcgacc tgctgatcga gatgaggaag
    16621 tcccacaagg cgggcaagaa gcacgccggc gtgaacgtct tcaccggaca ggtcgaggac
    16681 atgctggcca acgacgttgt cgagcccttc cgggtcggca agcaggccat cagctccgcc
    16741 accgacgccg cggtaatgat cctgaggatc gatgacgtga tcgcctccag gggcactccc
    16801 ggcatgaact ccaaggacat ggtcggcaag gacggcctgg gcgacacgga ctaaactcaa
    16861 aaaggagggg gttctcccct cctctcaaaa cacctttatt ttgatcgaca gtcaacgggt
    16921 gagcccacaa tggaagacag ctccagggaa acgcggcccc cgcaggcggg ggaggctcat
    16981 gacgagccgc tcaggccgga cgatgaaatg acaagaatca aggctgagct agaggaggcc
    17041 aaggcgcagg cggagaggaa tctcgaactg gccaagcgca tccaggccga tttcgacaac
    17101 tacaagaagc gcgcccagcg ggagaaggag gagcagatca aggccgcgaa cgaccgcctg
    17161 ctctacgatc tcctgggctt cctggacgac ttcgagaggg ccttggccgc caaggccacc
    17221 ccggaagagt tcagaacggg cgtggcatcc gtccacgcca acttacgatc attgctccag
    17281 tccaaggggc tggtggagac gccctgcgag gtcttcgacc cggcgctgca cgaggcgctg
    17341 tgcgtcgggg aaggcgagga gggcaaggtc ctggaagtat accagaaagg atactgcctg
    17401 ggaccgagga tagtacgcta cgccaaggtg aaagttggca gtggcagcaa cagaggtgaa
    17461 tcagatggct aaaatcatag gcatagattt aggtaccagc aactcggccg ccgcggtcat
    17521 ggaaggcggc cgtccgacca taattccgag cgcggaggga accagcatag gaggaaaggc
    17581 cttcccgtcg tacgtggcct tcaccaagga caaccagcta ctggtcggtg agccggcccg
    17641 tcgtcaggcg gtaaccaacc cggagggcac catcgccgcc atcaagcgca agatgggcac
    17701 cgattacaag gtcaccgttc tggggaagga gtactcgccc cagcagatat cggcgttcat
    17761 cctgcagaag ataaagcggg acgccgaggc gtaccttaac gaggaggtca ccaaggcggt
    17821 catcaccgtc ccggcctact tcaacgacaa ccagaggcag gccaccaagg acgccggggc
    17881 catcgccggt ctggaggtca tcaggatcat aaacgagccg acgtcggccg ctctggcttt
    17941 cggactggac aaggtcggca cgtcccagaa ggtcatggtc ttcgacctgg gcggcggtac
    18001 cttggacgtg acgataatgg acttcagcga cggggtcttc gaggtcgtct ccaccagcgg
    18061 ggacactcag ctgggcggca cggacatgga cgagctgctc atcagatacg ccgtcggcaa
    18121 cttccagaag gagaccggca tcgacctcac cgccgacaag atggccatgt ggagggtgcg
    18181 cgaggcctgc gagaaggcca agatcgagct gtccaccacc atgtccaccg aagttaactt
    18241 accgttcatc gccgccggag cggacgggcc taagcacctg gccttcaatc tgacccgcgc
    18301 gaagctagag gagctcgtcg agccggtggt caaccgttgc cgcgggccgg tcgagagggc
    18361 catgaaggac tccaacctca gcgcggacaa gatcaacgcg gtcatactgg tcggcggccc
    18421 gacgcgcatg ccggtcatcc agaggttcgt ggagaccgtg gtgggcaaga agatccagcg
    18481 cggtgtcgat ccaatggagt gcgtggccat gggcgccgcc gtgcaggcgg cggtcctctc
    18541 cggagaggtc aaggacgtgc tgttactgga cgtcacgcct ctctccctgg gcatcgagac
    18601 gctggggggc atcgccacca agctcatcga gcgcaacacc accatcccta cccgcaaatc
    18661 gcagatattc tccaccgccg ccgacgggca gaccagcgtg gagatacacg tgtcacaggg
    18721 cgagcggccg atggccaagg acaacacttc cctgggccgg ttcatgctca tgggcatccc
    18781 gccggcgccg cgcggagtac cgcagatcga ggtggccttc gacatcgatg ccaacggcat
    18841 cgtgaacgtc agcgccaagg acctgggtac cggcaaggag gccaagatca ccatcaccgc
    18901 cagcaccaag ctctcctcgg aggagatcga caagatggtc aaggaggccg agcgcttcgc
    18961 cgaggacgac ctgaagaaca aggagaaggt ggagatcatc aaccaggccg atcagctaac
    19021 atacgccacc gagaaggcgc tgtccgagct gggcgagcaa gcttcgaacg aggagaggac
    19081 caaggtagag gccctgatca acgacgtacg cgaggagatc aagaagggcg acgccgcggc
    19141 catcaaggcc aagacggaag ccctccagaa ggagttctac gccatatcca cccgcatata
    19201 ccagaacatg gcgcagaagc agcagacgga agggccacag caaggttccg cccctaagga
    19261 cgacaacgtg gtcgacgccg attacaaaat cgttgacgac cagtaggcga accgatggct
    19321 gagaagcgcg actactatga ggtcctggga gtggaccgcc aggcgggcga ggaagaggta
    19381 aagaaagcat atcgtcagct ggcccgccag taccatcccg acgtctccaa ggaggacccc
    19441 aaggtggcgg aggagcgctt caaggagata tcggaagcct acgaagtgct gatggacaaa
    19501 ccgaaacgtg agctgtacga caagtacggc cacgccggcg tcaacagtca gttccagggg
    19561 ggcgggttca actggaacga cttcacccat cagggcgaca tccgcgacat cttcggggat
    19621 gggggcttcg gcggcggaaa catcttcgat atgttcttcg gcggcggccg ctcccgcgga
    19681 ccgcatcagg ggcaatccct ccgttacgac ctggacatca cgctggagga agcggctgcg
    19741 ggcctgaaga aggagctgac ccttccgctg accgtgaaat gcgacgtctg cgccggcaca
    19801 ggctccaaga gccgcaagga agagatctgc ccgcaatgca atggcaaagg ccaggtgcag
    19861 cgggtggaac gccgtggcta ttctcagttc atatccgtcg gggcctgccc gaagtgcggc
    19921 ggttccggca aggacatcaa ggacccctgc cccgattgtg atggcgggtg gaccaggaag
    19981 cggcagaaga tatccctgga tatcccgaag ggcgtggaca ctggaatgcg tctgcgggtc
    20041 gcgggcgccg gcgagccgtc cccggacgga ggtccgcccg gagatctctt cgtggtggtg
    20101 aacgtcaagg agcacaagct gttccagagg gacggctcgg acctatacgc cacccaggag
    20161 atcaacttcc aggaagcggc gttgggcgcg accttggagg tgccgaccct ggaagggaag
    20221 atggccgagg tcaacattcc cgccgggacg cagccggggg aggtgcagcg gttgaaaggg
    20281 ctgggcatgc cgcgcatgga aggatacggg aagggcgacc tgtacatccg tctcaagctg
    20341 gtggtcccga agaagctcac cgccgagcag aaggaactat tgcgcaagtt cgacggcgga
    20401 gacggttcca agaagaagct tttcggccgc agcaaatgag cttcagtaca gaagcaggaa
    20461 cgctatcagg acgtgcagta cggcgaacag cggcaccagc ttgaacttca tcttcctggt
    20521 cttgtgccgg aaccacctca taccggccag ggcgccgaag ggaccgagca gcgctaccag
    20581 cagcaacgtt ttttcggaga tgcggcggtc gcccttccgg gccatcatct tgtcgtaacc
    20641 gtacatggcc agggccacca ggttgatcag gacataaagg ccggccaggg ccagaaaggt
    20701 cacggacagg agatccatgc tccccgatac cgctcggccg gtaaatcgtt ttgccctatc
    20761 tcgcaaaacg aaccagtccc tggcggcctt ttccattgga aacgattatg ataacgttgg
    20821 ccatcactaa cggctgataa tggccatccg gctaccttcg ttccagtcca cccagggttt
    20881 cgaccgccgg gtctggacgc tcttctatgg gcgtatcatc tcctctctgg gattctcagt
    20941 ggtgatgccg ttcctctcca tctatctgca caacgagctg ggcatctcca tgaccatcgt
    21001 gggcctggtc cttctgatct cggccgtggt gggcgcgcta ggccagataa tcggagggga
    21061 gctggcggac atcatgggcc gccggaagat aatgatcatc gccatggccg cccgctgcct
    21121 gatgttcctc gccctggcct acgtcatttc gggcggggcg gacatcttcg tgatcacgat
    21181 aatggtctcc ctgagcagcc tggccggatc gttcttcgaa cctgcgtcca acgccttgat
    21241 cgcggacgtc gtggagccga agaagcgcct ggaggcttac ggactcctgc gcataggcgg
    21301 gaacgtcgga tggacgctcg gaccgctgct gggcggtctg ctgtccatgg tatcctatcc
    21361 gttcctgttc ataatcagcg ccgccgccac tggaacggta tccatcatcg tcttcctatt
    21421 cgtggccgag agcatctcct ccggcgcccg ccgtcagaaa ctgtccctgc gtgacctcgg
    21481 ccggctgagg aacgaccacc gtttcctggc cttctgcctg atttccatcc ccctgttcat
    21541 tatgttcggc cagatggcct ccaactacgc ggtcttctcc accgagatca tcggcatcac
    21601 caacgccgag atcggctaca tctacgcggt gaacgggctg atggtggtct tcatgcagtt
    21661 ccccatctcc cgttccataa gccatctgcg catgaccaag gccatggccg tcggttcctt
    21721 gctctacgcc atcggctacg gcatcgtggg gctgacgccc tacctcggag tgggtctgcc
    21781 gcactggctg ttctcgccag ggttccttta cctggcgttg tgcatgttca ttgtgaccat
    21841 gggtgagatg gtcgtgtctc cgtcctccat gaccctggtg gccaagatgt ctcccgagtc
    21901 ggaacgaggg cggtaccagg gaatgtacgg gctggtgagc aacttcggct tttccgctgg
    21961 gccgttcttc ggcgggcttc tgttcgacgc cttcaccggc cagtcgatat tcatgtgggc
    22021 cggcatcggg tccttcggcc tgttggccgc cctgggcttt ctgggccttg ggagacgcat
    22081 accggagagt acggaccgca tagacgaggg ctagtgcggc aggtactgga tcgaacgcaa
    22141 atctccgtcg atgcgggcca gcattcccat gcccgcccgg gcgtccagca tggcgaagta
    22201 ggccacgatc cccgtgtccc gcaccatgcg catcagttcg gcctccatta tggcctggga
    22261 gatcagctcc tcatcggcca ggctttcgaa ggagaaaaga tagagtagca ggcggtccct
    22321 cgccttcgat gagcgcagga ggtccaacgc ctgctcggtc cgctccctgg acatgttccg
    22381 gcccatgacc acgaacgccg gctctccgtc cgccgagcgc aggctcacgc attggaacgg
    22441 ggacttgtcg tcgacgacct gcaatccgtc accggcggcc cggacccgca gttcatcctc
    22501 aatgaggaaa gacagatatc tagaggggtg ctccaaggcc aggtccggaa gttcctcctt
    22561 caggaagtcc cggcaggtca ccacgcattt gtcccgcacc aggtcagaca ggtccttgcc
    22621 gttcacgacc gtccattcca gcctcgatta tttcaccgtt gcgaaatcat tctcgttcca
    22681 tacgaaacaa gcgccgggag accaaggatt atatgctgcg cgttccggtt aacttccgat
    22741 gaaggtcgtg gccgtggtca ccgaggactt ccgcttcttc tacgaaacgg tacggctcct
    22801 caaggaaaag ggccagcctt tcatctcgtt aggtttctcc gaccccatgc cgctgaacgt
    22861 ggaactggtg ctcaccacgg aaggggagag gaagcgtctg cgcgggcgca aggtcatagc
    22921 cagtgacgat ccggcctggg cggtcaaggc cgccctggtc ctattgaagg gcggttcctt
    22981 caaccggttg atcgtcgggg tggaccccgg gccccggccg ggcatcgcca tactgggcga
    23041 cggaaagctc ctgttggccg aaacgcttct ttctccggag gaggtggcgc cggcgataag
    23101 ggaccttctc tccttcgtga gcagcaacga gctactgttg cgcgtgggtc acggtgatcc
    23161 gaccaaccgg gaccgcatca tcggctcgct ttgggacatc acccgcaaca tcgagatggt
    23221 cgacgagacg tccaccaccc ggcacaccgg tcacccggac gccgcggcgg ccatcgccca
    23281 tggccgggga gagctcctgg cgtctcgtcc ccgcgtggcc cccaccgatg gcgaggtgcg
    23341 ggacattcag aggctcagtc gcatcgagag cgggggagcg ataaccataa attccgcatt
    23401 ggccaggcag gtggcggtgg gagcgttcac cctgaacgag gcgatagaaa aacataaacg
    23461 gaaaggggtt tcagagggcg acccttgaga aggccggcac cctggccagg atcatgccct
    23521 gtatctgcac cggctccagc cgtatcgcca acttgagggc ctcctgcagc ttccactcat
    23581 gctcggagta gatggtgaac agggtctcgc ccttgtccac cttgttgccg cccttcttgt
    23641 tcagcagcag cccggcgccc ttgtccttcg gcgagccggc ggtgcgggcc acccggacca
    23701 gggacttgtt caggatatgg ccgacgtacc cgctctgctt ggcgatgacg tccacgctgt
    23761 actgcccgac cttgatgtcc ttggaggtga tgcctggctt gccgccctgg gcctccacta
    23821 tctcctggaa cttcttgagg gcctttcccg actccaggat ctgcttggcc ttctcgacgc
    23881 cctggtactc cccgcccatc tcgaacagca tgccgcacat gctgagcgtc ttctcgatca
    23941 cgctgttcgg tcccttggcg ccctccagga tggatatggc ctcgatggac tccagggccg
    24001 ggccgatggc cctacccaac ggctggccgc cgtaggttat ggcgcattcc acccggatgt
    24061 ccagctcctc accgagctga atgaagtccc gggcgtagcc cttggcctct tccatggtat
    24121 ggaccttggt cccctcgccc atgggtatgt cgatcaccag atagttcgct cccaccgcct
    24181 tcttcttagc catgacggac gctaacaatt gagcgtgggg gtcgatcccc agcggatatt
    24241 ccgccttgat gatcaggtcg tccgccgggg ccaggttgag cgagccgccc caggccagga
    24301 cgccgcccac ccgttcggtt atctccttga gctgggccgg ggtcagggcc acgttggcga
    24361 aggtctccac gatgtccgag gttcccgcgg cgctgctgat ggcccgcgag gaggtcttag
    24421 gcatcttgca cccggcggcg gccattatgg ggacgatgag caaagtgatc ttgttcccgg
    24481 ggcacccgcc gatgctgtgg tggtcgtata tcgggccgtt gctgaagttg attatctccc
    24541 cgccggccac catggccttg gtaaggtcga cggtctcccg catgttcatg ccgttgatgt
    24601 agagcgaggt gacgtacgcc gacagttcga tgttcgacag ggcccgggaa gagatgtccg
    24661 cgatgatgct ggttatctcc tcggtggtca gttcctgccc gttcatcttc ttcttgatat
    24721 attcgaccga ctcgggcttg ctggccgcgg aaacctccac caggtccccg tccttggact
    24781 gcatggtctc ctgcgagctt cccatcaggc cgatctcgcc cttcttgatc acggtgtcgc
    24841 tggtggtgac aatggccacg gtgaccttgc cgttcaggga gagcttcaca cggtccttct
    24901 cccggagccc gagctcagcg cagtcgaagt cgtgcaacag cgcggtaacc tcaccagtgt
    24961 ccacgtctat atagcgggcc ttgagcttca tgccaatccc cacttcttga tggccgctgc
    25021 cagctcggcg tggtccttgg cgtacacgtc caacggaatg ttggccgccg ccgcgtccac
    25081 cgcctggacc atggccctgg cgccgccccg gacgccgccg ggatggccgg agacgcctcc
    25141 cccggcctgg atctgcagtt ccgttcccgc gatctccacg aacttcttga tcattcccgg
    25201 gtgcacgccg ccggaggcga cgggcatgac tcgtttgtaa ggcagttctt tcgtcaggca
    25261 catgtcccgg ttggccagat cctcgtgcgc cgcgcccttc atcttgccca cgccgaacgt
    25321 gccgacgtgc aacgcgtcgc cgccgaccat cctggacagg gtggcgaaca ccttcatgtt
    25381 gatgccgtgg tccaggttgc gggtcatggc cccgtgcatg gtgcggtgaa cgtgaatggg
    25441 cagctttatc gatgggtcct ccgccaggac ctgtatggcc ccgaagccgc aggtgagaac
    25501 gtccaccatg agctcggtgg cgcccaggct ttgcgcccgt tcggccacct ccaatatctg
    25561 gtgcccgttg gtgctgacgt ttatcgcatg catcatgacg tgcccggtct cgctcttcac
    25621 ccggtcgatg gcctcnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    25681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnacgcc
    25741 gccgatgtcc agggagaagt cctccaccgg gaaggcgatg gtggccatgt tgccctctat
    25801 cttggtgacc ttgccgctcc gcttcaggaa gttgtcctcg ttgagggtgg acagcttcgt
    25861 ccaggtcccg gtggactgct cggtggcgat ggccgccgcg gcggtggtca tcttcaggtc
    25921 ggtgccgacc ttgtacttgc atatgacatg cgaatcaatg tcgattggcg cgtccagatg
    25981 taggtatctc tcttcgtatt ccattttatc aatcctcgtt gaacatgaac tcgtaaccca
    26041 gctccttcac gatcacctgg taggcggcgt agggcgggat gaccccgatc tcggtgatga
    26101 tggcgtcgat gtactccggc ggggtggcgt cgaacaccgg gttgaagacc ttgacctcgg
    26161 gcgggacctc cccaggcttg acgacctcgg tggcgtcgcg ctcctcgatc ttcaccatct
    26221 ccccgtatat cgtgcgcggc gagaatttga acgtttccgc gcagaccatg aacgggaccc
    26281 gcgcctcgtg agccgcgaga gccacctgcg aggtgcctat cttgttaatc aaagcaccat
    26341 tggaggcgat ggtgtccgcc cctaccagca ccaggtccat gtccttcatc acgtagcgca
    26401 cggcggagtc gatgatcatg gtgaccggta ttcccaattt ggccaggtcg ttggcggtga
    26461 gcactccctg acgccacggg cgcgactcgg tgcagaacgc ctcgaagcgc ttgccctggg
    26521 cccaagcctc ggccatgact ccgatggcgg ccttgctgtt gcaatgcgtc aggaccttgt
    26581 caccgtcgtt tatgcggttg gcccccagct tcccgatggt cttgagggcg ttcttggacc
    26641 gcttcacgaa gtggtcggcg ttcttgacca ccatgttgcg atagtcctcg gccgtggtga
    26701 gctgagaggt gtccttgaag acgaactgca ccccgttcca gagcgatatg gccgtaggtc
    26761 gggaggcgat aaggatatcg cgagagcgct cgacgcggga gcgaagctcc ctcagatcgt
    26821 tcccctgata ggcctccgcc tcttccttta tagcggcggc tgccctcctg gctatctccg
    26881 cggcgccgcg tatctccatg gagcgaatgc gccccgccac atcctcggcc gacatcccgt
    26941 aagtatcgtt actacacctt gataaacgtt cttgcccagc gttacaatcc caagcgcttg
    27001 cggagctggt cccagggcag ggcgttcagc accagctccg gcggcaccca tccccttttc
    27061 gcagtcgcca cgccgtaaag aatgtagtcc agctgccgga cgttgtgagc gtccgtgtct
    27121 atacttatcg tgacgccacg ttcccgggcc atggcgcaat gcacgtcgtt catgtccagc
    27181 cgctccggga aggagttcac ctccatggcc acgccatggt ccttggcggc ctgcatcacc
    27241 ttgtccatgt cgtacgaata gccctcgcgc tcccctatga tgcgaccggt aggatgcgcc
    27301 aggatgttca cgttctcgtt ggagaccgcc gtcaccagac gctcggtcat ctccgcgggg
    27361 gtcatcttga agcgggagtg cacggccgcc accacgatgt ccaggtcctc cagcagtttt
    27421 ggtgggtagt ccaggccgcc cttctcgtcg atctccacct ccgtgccgat caggaggtgc
    27481 aggtcggggt gagcttcgtt cacctttcgt acatgctcca tgctctccag gagccgctcg
    27541 gcgctcaatc cgttgccgat ggtcagcgaa tgggagtggt ccgtgatggc cagatattcg
    27601 tagccgtggg cctcggccgc cctggccatg gcctccacgg aatcaacccc gtcgctcgcc
    27661 tccgagtggg tgtgcaggtc gccgcagatg tcggagagcg tcacgaccct gggcacctgc
    27721 cctttccggg ccaggtccac ctccccgcgg tcctcccgca tctccggcgg catccactgc
    27781 aagcctagta actcgtacac tccctcctcg gtctccccgg cgaccttcga tccgtccgag
    27841 aggcgaaaaa cgccgtattc gttgagcttg tagccgagat cgttggccag tgaccttacc
    27901 ttcacgttgt gctccttgga gccggtgaag tattggagcg ccgctccgaa cgaggaagga
    27961 tcgacgaccc gcatgtccac ctgcaccccg tcctgcaggc gtatcgacgt cttcgtcgcg
    28021 ccccgcagca tgacctcggc cgtctgcggg aaggacacga acgtctccat ggccctttcc
    28081 gcctccgagc tgcccaccag tatgtcgatg tccccgatgg tctccttcat gcggcgcagg
    28141 cttccgccca gactgaccag ctcgaagccc cgctcccgca ggtgctcctc caacgctcgt
    28201 ccccgcgggt aggcgtaacc gaggagcatg cgcccctggc gggactccag atatctaatg
    28261 cctttcaaga tgttctcctc ggtcctttcc ccgaaaccct tcaaggtccg gatgcggtgc
    28321 tgctccgccg ccgctttgag gtcctgaagg ttggtcacct taagttcctt atacaaacgt
    28381 ccagcggtct tcgggccgac gtccggcacc tgcatgacct gcaacagtcc cgccggaaat
    28441 tcgttgcgca ggtcgatcag gtactgaagc tcaccggtac gcaatatctc cacgatcttg
    28501 tcgttgatgg cctttcccac gcccggcacc tggtccagat gtccccggac gtagaggtcc
    28561 ttgatgtctt cggtgaggga cgatatctcc ttggccaccc gccggtaagc cctcacctgg
    28621 aagaaggtgt cctcctttag ctccaggagg tcggccacct cttccagtac ggaggccacc
    28681 ttggcgttgt tatccactta cttcctcagt cctccttctt gcagacccag cggcattcct
    28741 tgtccccatc ggacatccgg tgggtctggc accagccgta ttcggggttg atgacctcgc
    28801 agaagccgtc cacgaacttg ccgaagaggg agcaaagctc cgggggctgg ttggcgaagg
    28861 ggcactgctt ggcgaccttg atgacggcga tctcgctctt ctcgacgatc tccccgcgaa
    28921 cgcccagcgc accctcccag aggtcgatga gcgaggagat ggctatgccg tcgcggtcca
    28981 ctatctcatg ctcctccaga gcccgcacgg cggccttctt gcctcccgtt cgcattatcg
    29041 gtcccatgag gtccagcgtc ctcttgggcc cctgcgacct gaccatctcg gtcaccgccg
    29101 aagctaggaa ggtatgaagg atcttcttca tctctggcga attactgttg atgaccacgg
    29161 ccttcaccac cgtgctccac caaatggtta tggcctcctt ggccatgctc tccatctcct
    29221 cactggtcag attgttgtcc ttatccggca tagaagttcc acctagggct gtgcgcacgt
    29281 cccgctcaca gcatctacgt tcagcctagg tatatttttt cccgagcgtc gcggttacgg
    29341 aggacgaaag ggaccaacgg acggctctac gaacgttgat atataatgct ccgaatgaaa
    29401 ttattccacg gtggaaaatg ttcgagggta acgtcatgtt catcggcaac aagccgatca
    29461 tgagctacgt tctgaccgca gtgcccaagc tccaggagct gggagagctg accatcaagg
    29521 cccggggaat gtccatcagc aaggcggtgg acgtggcgct gattctgcag gaccgctaca
    29581 tcaaggaatg ccatgtcgat gggatcgaca tccgaaccga ggtcctggac ggtgacaacg
    29641 gggagaaggt caacgtttcc tcgatccagg tccacctgcg ctccccggtt ccgtaagact
    29701 gacgtagcat tcgccatcga gggacgcacc aaaagcgtaa ttatccgggg atcacatttt
    29761 tactcaagcg gacgagggac gaacatgagc gagctcaacg ccatctacat cggccagaag
    29821 ccaatgatga actacgtcct ggctgccgga aagagactgg tagggaacgg ttccagcgtg
    29881 ctcatacagg cccgcggaag gtccatcagc aaggcggtgg acgtggccct gataaccctg
    29941 gaccgggcga agggcgagat caagctgggc gagatactca taagcaccga ggtcctcccc
    30001 ggcgcggacg ggaacccttt gaacgtttcc tgcatcaaga taatcctcag ccgggcctag
    30061 gacatctcgt tgatgagcag gttcacttcg ctctccggca ggttcttggg ctcgtaggga
    30121 agcagaagga gcgaacgggc ctggttcaca tcgtccttca gcttctgggc tatcttcagg
    30181 aaggaacgga aatcggtgtt ggtgactatg taggtcatac catccagcag tatcaccgac
    30241 ggccgtccct tgttcttgtt caggaagtta cggatgatgg tctgcatctt cgctgtctcg
    30301 gtcggaagga tgtactcctc gcggtcctgg tcccctccca tggggtcggc cttggtaagc
    30361 cagagcacag tgcattcctt gcccacgaac tccttcactt ccttggggga tgctcgggat
    30421 atgcaaagac cgtcccatcc ggccctgacc aggtcccgga agtcggccaa tgcctgctgg
    30481 ttcccctcgc ccttgatgag caaggtcttt cccggggcgg cttcccggcc cggctcgtcg
    30541 ggcttctcct cgatggcgtc caggctggat ccgagcgcat gttccagctc ggacttcttg
    30601 gacgccttct tcttggggat ggagttcctc tggttcttgg ccagtatctg gatctccgtg
    30661 ctggtgtagc tcttgcggca ggtcatggcg ataagctcgt ccaaagcctc ccgcatgccc
    30721 tcctcgtatc ccttcaggta cccctcggcg tactctctgt tcaacccatc ccttccctga
    30781 taatgaatgg cggcggtggc ataactaact agcggaagcg aatgatttaa tggggagcga
    30841 tgggatgaag gcccatgggt tcccgagccc gcttccgcgg cattaagaag acgccaaaga
    30901 acatggagag ggagatgctg gcaacatccc agcgactttc tgacgatcca tctctggtcg
    30961 taccaaagct tctggacgag gtgcggaagt cgcccttcgc ctatctggag aagatgctct
    31021 ccaaggtcca ggaccatcgg gacgacgcgg agaagctcat aaagatggcc ggcaagggcg
    31081 atcagttcgt acgggcctac gcggccgcgg tctcgctgtc cgcctccggc aagctgcctt
    31141 acctcaccac cgccactctg ccggtcggcc ctgtctcctt cgccatgcgg gggacggtgg
    31201 accgggagaa gctgatcgcc ttgcagcact tcgacgatcc ggacctgagg ctcctggcct
    31261 actgggacat ggcccgcgag gaccgtctgc acatctactc cacggagaag gggttgtacg
    31321 cctccgtctc cgggcccaag gctcccgagg aatacgtcaa ggagatgctg gagaatcttc
    31381 cgtaccggac catcgagaac gattgcgggc acgaccgtcc ggctgtgcgg gtgaaatgga
    31441 tatcggctaa caaggaggtc cgggtgtgcg cggagtgcgc ttccgacgtc aacaccgccc
    31501 agcatctcat ggcccgcgtg gccgctcccg atccctacga cgacatcaag gtgagcgtgg
    31561 agcaccgata cggcggcggt cgtccggaat gctcggggga tttctccacc cctcccgctc
    31621 tgattaagag gtacatcgac ggggaactgg acgactccgg tctcatcgcc gagcacatca
    31681 aggccaaagg agagtggatg cgctcccgcg ggcaggtcta tatcataggc caggaatgct
    31741 tcggaaagga cggcgaggcc ttcctgaacg ccctcaaggg caacgagcag gagaaggtcg
    31801 ccctacggtc ggtgctggcc ctgaacgttc ccatcgtatc ggaccagaac caggccggga
    31861 aggtcatcag cgagctgtgg gacccccacg ccag
//
LOCUS       DAOPZI010000015        31673 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1354_length_31673_cov_10.231387, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000015 DAOPZI010000000
VERSION     DAOPZI010000015.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 31673)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 31673)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31673
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1354_length_31673_cov_10.231387"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..851
                     /locus_tag="PKM11_04305"
     CDS             <1..851
                     /locus_tag="PKM11_04305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HNX47762.1"
                     /translation="LWYIRIPRALGVIGVGVGLSVAGAVMQALIRNPLVDPYITGVSS
                     GAALGVTTAVLAGVTIGGLGIFVTPIMAFIGAVLAFLFTMLLAEAAGGRSISYVLGGV
                     IVGIALQSGTTILMYFNADRLHSVLYWLFGSFSTLNWQSTTIIVLCVSVLAAIMLLYA
                     KEFNVILLGDEQAQQLGMNVKRFKTGMFVLVSALTAVCVAFTGIIGFVGLIVPHLVRM
                     LIGGDHRLLLPASMVVGANILLIADIVCKTAVAPSELPVGAIISIIGAPFFGYLMIRM
                     GKEYVM"
     gene            841..1704
                     /locus_tag="PKM11_04310"
     CDS             841..1704
                     /locus_tag="PKM11_04310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47763.1"
                     /translation="MSCDEELTVKVDNLSFSYGAKRNLCAKTLKGITIDAKKGQLIGI
                     MGPNGCGKTTFMRCINKVLKPQEGAIYIDGKDLDRLKMMEVAKICANIPADVPDDFHL
                     SVEEFVALGRYPFVTGIWWEGAKDEELVRDAMKAYHVTHLKDRKLGELSSGEKARVLL
                     AKGAVQQPKILLADEPSAHLDLKFKLQVMQALKDLSRQGVTVITASHDINLIAKYADL
                     VIIISEGGIVSYGPPAEVINEDIIRAVYGVEVSIIRDNGELYVIPLRPAEPEKGDDED
                     PRPCEKGIVAD"
     gene            1661..2806
                     /locus_tag="PKM11_04315"
     CDS             1661..2806
                     /locus_tag="PKM11_04315"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: protein motif:HMM:NF012382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HNX47764.1"
                     /translation="MKIQDLVKKELLPIKRPVHGGQGWKLPGVEDFSHNLNPYGPPAE
                     LPRLVAEASEQLSHYPDDTATEFREAVATLHNVWPENVIAGAGSAELIRLFPEVFMSR
                     KARVIIPRPTFSEYSHACRMQGANILDVPLVEGEGFRLDMNAIREKLPLARALYICNP
                     NNPTGTVETKRRIMELVDECESTGKLVFLDETLLDLVDDHESISCMSEVQSHENLFII
                     SSLTKSFAIPGMRVGYGVGGVEIVDMMERARLSWNLGVIEQYVGARLLRDHQDHVRKA
                     AQMMASERARIKKAVDSTGLLSPLPDQCFFFFTRVADPKRSGQDVVEHLLPRKVLVRD
                     CSTFGRPFDRFIRFSVKTPEKNDMLIAAIEDTAREIRNTAFGARMHV"
     gene            2799..3794
                     /locus_tag="PKM11_04320"
     CDS             2799..3794
                     /locus_tag="PKM11_04320"
                     /inference="COORDINATES: protein motif:HMM:NF002281.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HNX47765.1"
                     /translation="MFELVPYALLTIIIALLIDRFIGEPPNSLHPVVWMGKVISFFDE
                     RIARGHPRRERLFGALMALAVILMFSIAVLLLMALVRDSLGLLVWAVVGGILLKTMFA
                     MSAMGKHTEPVRQALLAGDLELGRQKAAMMVSRDVSQLDKEHVISCAAESAAENTVDS
                     IFSPLFYFGLLGLPAAVAYRVSNTLDAMVGYLDDKHRYVGWFSAKLDDGTNFVMARAA
                     VPFILLALFILGKDWNAGWKASKKFHDQTLSPNKGWHMSAFAGGLGIRFEKIGWYVMG
                     DGPLPSDPEVLRDTIKVMTMASYLFLLTVVIPLYLLVGAEVQVFVEDILLGLIGV"
     gene            3796..4932
                     /locus_tag="PKM11_04325"
     CDS             3796..4932
                     /locus_tag="PKM11_04325"
                     /inference="COORDINATES: protein motif:HMM:NF014060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide amidohydrolase"
                     /protein_id="HNX47766.1"
                     /translation="MKLSEVRIEKGAVDGHKYVAIRLPRRLRTLASTILNGGLGETDS
                     VLMLQVSLHYDHADPVEHLRSLLPRLGLPSDTVCFMTAAELDKAFCSKGLEQNGSEAL
                     AFVSAGISNAIRAGESSREGSVPHRQVGTINVMVVTDEPLDDCALANAIMTVTEAKAA
                     ALQDHHIPGTGTTSDAVLVMCPSDGERCLWSGSSSDHGIAMAVAVRSALGESIARWKG
                     ANGDSVHFLRHLAIRGITYDDMWNAVKEMNALDPAWDEAEIRKRFERKLEMLAKDINV
                     NALLTAAILLEEKGRYGQLYGLNEEKYQEDPVHLLADELLGIALAEYIGGSKCVFEYI
                     RYDKKKPGILSKLGPFMDDIVASLIGATMSTIYSEILEGEGRLS"
     assembly_gap    4970..5069
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5070..5468
                     /locus_tag="PKM11_04330"
     CDS             <5070..5468
                     /locus_tag="PKM11_04330"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: protein motif:HMM:NF014685.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008818 - cobalamin 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0051073 - adenosylcobinamide-GDP
                     ribazoletransferase activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HNX47767.1"
                     /translation="TGQAELLFFPLIAEIMNKNAMVFCAYGGKAREGLGNSFVSNTKG
                     KQALLSLVLSVLLAFGAILLVCLPTGYWHVDKIALFTVAGGLVSAIVGLLVGRVAMKN
                     FGAVNGDVMGATNEISRPVVLIAMLLLVAL"
     gene            5465..6091
                     /locus_tag="PKM11_04335"
     CDS             5465..6091
                     /locus_tag="PKM11_04335"
                     /inference="COORDINATES: protein motif:HMM:NF012695.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HNX47768.1"
                     /translation="MSVAALITAGGRGTRIKEMGVEKPMVQLHRRPMIDHVLEQMMLV
                     DEISSVYVSVSDNVPNTRRHLEQMGVNLLETSGTEYCHDLIQAAEDIAEDHIFICPAD
                     LPLLRAELVSDVVREFLKRKEQSLTVGIPLEKALEFGVDVTFYENVNGQPLMPCGVSV
                     VDRKRMLTREFLPGSYYVAETPEVVVNVNTMADLKKAEKELHRRFTCP"
     gene            complement(6078..7181)
                     /locus_tag="PKM11_04340"
     CDS             complement(6078..7181)
                     /locus_tag="PKM11_04340"
                     /inference="COORDINATES: protein motif:HMM:NF003372.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00303 family protein"
                     /protein_id="HNX47769.1"
                     /translation="MHKADIIYALEEQAGRNFVAKVWGKRPTYAVVIGNTETAKIPGV
                     SAAGAVPAITDFTPAADVELLYYGRCKCIDGVPVTPTGVPTPGIITMSALQLVSMPTF
                     AINGGVNVRPHTPYFELEGSAGEDIRTGKALKDPRRVYENGVLLGRELAKNSEYLVIG
                     ESIAGGTTTALAVLMAMGYDGQGKVSSSMIENPHSLKEKIVQEGISKSPFSMAEMKAD
                     PLKAAQAVGDPMMPAAAGVVAGAAESIPVIMAGGTQMAAVMAIVKGLAPNVLSNIALG
                     TTKWIVNDRSSDVRSIVKQIGKVPILAADLDFGPSKHDGLNVYEKGLVKEGVGAGGIS
                     VAVFLASQGKIGKEQMLSQVEKNYVQLMRIMGK"
     gene            complement(7287..8336)
                     /locus_tag="PKM11_04345"
     CDS             complement(7287..8336)
                     /locus_tag="PKM11_04345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47770.1"
                     /translation="MRKLIILLDGAADERISIFKNRTPLEAARKDFMDCVARDGKVGT
                     TDGKDYTHTFLLELLTGKPYDVPRGVIEAFGLELPIGEGRVAYRMTPAKVHDHNVEWY
                     YNITCDEEMFLQRAIIKNRSKLKDMDPKILAYHGGKGVLTIKGDEILDLPKPPGPAQI
                     SSEDLGPFLDFAKGVRESTSGIALLPWGGGLGKVAVDVRREISKVPDLTVISKSPSAL
                     GVGKFLGMETVRVPGFKEGIKLAAQVLDKNDVFLHIEETDDISHKCNPKNKLMLIEEI
                     DRELSRYEKRFQECRVALLIDHGASSVTGEHMRMKVPYAVCGGLRKGRGKKGFHENDG
                     ENVPLGTLLDTIFED"
     gene            8441..8956
                     /locus_tag="PKM11_04350"
     CDS             8441..8956
                     /locus_tag="PKM11_04350"
                     /EC_number="3.2.2.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR04274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033958 - DNA-deoxyinosine glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-deoxyinosine glycosylase"
                     /protein_id="HNX47771.1"
                     /translation="MAVSDDQGRERRFGLPPVVGNAPTVLILGTIPSVLSSRKGQYYG
                     NPLNHFWRLMGEALEETMPDDYRARCETLTRNGIAVWDVLAECDIRGSGDHSIANPVP
                     NDILGFLEGNRSIRHVFINGKAAHRFYLKFLEDAFAGQVTVLPSSSPANAMRRADRRE
                     KWVEIGKVLRS"
     gene            complement(8953..11142)
                     /gene="hypF"
                     /locus_tag="PKM11_04355"
     CDS             complement(8953..11142)
                     /gene="hypF"
                     /locus_tag="PKM11_04355"
                     /EC_number="6.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003998 - acylphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HNX47772.1"
                     /translation="MRITVRGVVQGVGFRPTVHRLARSMGLHGYVQNNGSNVVIEMDG
                     DAEEFVRRLKQALPPLAHLDEVVISPGLPEPELRTMGFKILPSQQGIGGVGIPNDTAV
                     CDRCLKEMFDPSDRRYLYPFTNCTDCGARFTVIEDLPYDREKTTMRPFPLCPQCQQEY
                     GDPDDRRFHHQTVTCPVCGPRYYLLDRDGERDYERPIARFASKLQDGKIGVAKSWGGM
                     HLCCALDQLSHMREWYRRKEKPFAIMVRDLKALERYGRPSDQDVKLLTSSHRPIVLVP
                     KVDNEITELVAPGLDTIGVFLPYTSMQHLLFHHLEEDALVMTSANVPGEPMVLRESDA
                     LTLGADMYLMHDRDIANRCDDSVVRSFLDKTYYIRKSRGHIPSHIEFPLKGVAIGVGA
                     QEGLAGALSFDRRLYATQYIGDATSPGVLEFLEESLKYLRRLLGADRLDAIGMDLHPG
                     HSTRRLAKRWAEESGIEPVEVQHHHAHAAALLVESKLDDMVAITVDGTGYGDDGVAWG
                     GEVLISNLKEYRRVGHLKEVPLLGGEKAVYDVRRIAFALAEMSGGGLDYFNEGERELF
                     RKMMPRSGTSTSFGRVLDGISCYLNICQYRSYDGEPAMKLERYLNLARNLDLVPTVRH
                     GNVIDTPAMFRQMMNVRGNQADRAGSMTYAMVRGLVDIASEKAEDEGIEHIGLSGGVS
                     YNRAISTWTKDLVEARGLKFVCHDLTPNGDGCISTGQCAVALSRTGN"
     gene            11235..11618
                     /gene="gcvH"
                     /locus_tag="PKM11_04360"
     CDS             11235..11618
                     /gene="gcvH"
                     /locus_tag="PKM11_04360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HNX47773.1"
                     /translation="MSDVPEGLHYTKDHEWAKVDGDIVTLGITDHAQDELTEFVYVQL
                     PKKGTKLGKGDVLAVVESVKNTADVYAAVSGEVIDVNGPLDDDPSQINKSPYGSGWIA
                     KIKMSDKGELKKLMDASAYRKHIGE"
     gene            complement(11620..11850)
                     /locus_tag="PKM11_04365"
     CDS             complement(11620..11850)
                     /locus_tag="PKM11_04365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47774.1"
                     /translation="MTCYFRHLDPVFLRAGLQIDIDNRKRVDMIIHEMVGVEYKDCTQ
                     TWAAVKEMLKDEDAFVERLRAECQAHNIYLDY"
     gene            11938..12393
                     /locus_tag="PKM11_04370"
     CDS             11938..12393
                     /locus_tag="PKM11_04370"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HNX47775.1"
                     /translation="MKDKLQEGDTSPDFSLPDQDGRTVSSSDIKGRKALVLYFYPADF
                     TKVCTMEAVAFRQMHEQFQAAGAEIIGVSSDDVKTHKEFAVEHELTFTLLSDEKEGLR
                     KAFGAYGIGGTPARTTYVIDRDWKIRMVYNSPLRSKEHAEEAMKAIRAL"
     gene            complement(12394..13179)
                     /locus_tag="PKM11_04375"
     CDS             complement(12394..13179)
                     /locus_tag="PKM11_04375"
                     /EC_number="2.4.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5'-thioadenosine phosphorylase"
                     /protein_id="HNX47776.1"
                     /translation="MQAKIGIIGGTGVYDPKMFELKGTVRPNTPYGPASDEIQVGELK
                     GVPVAFLPRHGRGHVIPPHMINYRANIYALKQLGVERIISPCAVGSLQEEFKPGEIVL
                     VDQFIDFTKSRKYTFFDGPKTVHIGAADPFCPEINSLFAKEAKKAKIPVHNGGTYVCI
                     EGPRFSTRAESKMYRAFADVIGMTLAPECALAREMEMCYTSLAMITDYDVWADHPVDT
                     ATILRTMAENMDKIRKLLSTTIPKIPEERKKCACGSVLADAGA"
     gene            13336..13860
                     /locus_tag="PKM11_04380"
     CDS             13336..13860
                     /locus_tag="PKM11_04380"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HNX47777.1"
                     /translation="MEKSEVNPIWACRAFPAFPVTLVAVGDGNGNNNIITVALVHMFS
                     FNPPVLGIGISPARHSYEMLEASDDFSINIPSKDLVEEVLYCGQRSGRDVNKFEDCGF
                     EPKQGKKIRSPVIEECAVSLECVKRQRVDAGDHVWYLGEVVHAEMAKDADREKSLMYW
                     SGEFRLLGDVIRKR"
     gene            13915..14448
                     /locus_tag="PKM11_04385"
     CDS             13915..14448
                     /locus_tag="PKM11_04385"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HNX47778.1"
                     /translation="MEDKVDLDNMGAVMALPPAPVVLVGVGDKEKNIITVGMFNVFSV
                     RPPILGIAVTTSRYSYKLLEENDEFTINIPGKELLDKVLACGEKSGADTDKFKLTGLT
                     AVKGKRTKAPRIAECLINIELKKTQSFEVGDHTWYLGEIKHTDIVEKYDRKDALLYWD
                     GEFWTAAAKPLKVLRPD"
     gene            complement(14434..15261)
                     /gene="pheA"
                     /locus_tag="PKM11_04390"
     CDS             complement(14434..15261)
                     /gene="pheA"
                     /locus_tag="PKM11_04390"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: protein motif:HMM:NF008865.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HNX47779.1"
                     /translation="MIVAFQGEKGAYSEDAVFSWDAEAKALECPEFLDLFDAVRSGRA
                     DLGMLPVENSIEGSVTAANDLLFRSDLKVVGEVMVHIRHCLIGHPDAELADVRRVYSH
                     PQALAQCRDLLTAHPEWQKVPAFDTAGSVRMIKERGMRDEAALASRRAASTYGMKVLL
                     EDVQSVRNNITRFFVISREGSKVKGNKTALAFTTKNQPGALLECLKAFASHQVNITKL
                     ESRPWQGRTWEYVFYLDLDGDAREERVAEALAVLRESASCVRMFGSFIKAVQPSVGP"
     gene            complement(15263..16627)
                     /locus_tag="PKM11_04395"
     CDS             complement(15263..16627)
                     /locus_tag="PKM11_04395"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR00657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HNX47780.1"
                     /translation="MAELKVLKFGGSSLKTGKNMRQVAEIIIAEKEKKAVVLSAVTGV
                     TEMLVQFISRTRSEEDVDAFMKDITKLHIDLIKDALSTDKGRAKAMEELIAKLVKLER
                     MLYGSCYIEEVNPRIRDYVQCFGERLSVIMLAALLNEMGSKARPVDADEVGIITDGVY
                     GTATVNMEATRSNIRPKLMKMLQDDVTPVITGFFGRAPEGSVTVFGRNGSDYSAAAVA
                     NAMGASSLEIWKDVDGFMSVDPKIVPSARAIPRLSYDEAAELAYFGAKVVHPMTMEPA
                     RSGNIEIRVKNVFRPEAPGTAIGGTGNVDKSIKSISCMKNLSLVKVFGEGTGYKLGVL
                     ADVASLLREAEINIYSVVTSLTCIGLLIDKKDVAKAQKVLAESGATRVETHTNFALMC
                     IVGEGLGHHKGLASRVFKAVAKEGVNVGLISAGASLVAYHFTVDEADLDKATKAVHEE
                     LFGC"
     gene            complement(16615..17274)
                     /locus_tag="PKM11_04400"
     CDS             complement(16615..17274)
                     /locus_tag="PKM11_04400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase
                     domain-containing protein"
                     /protein_id="HNX47781.1"
                     /translation="MRAELHTHTLISDGELLPIELARRAFVKGTKHMAFTDHASLSNL
                     ERVITEGRRDAELAEEWGMKVLAGVEITHVPARRIDEVVSKARKLGAELIVIHGETIS
                     EPVEKGTNYAAVMNPDVDILAHPGFITLEEAQAARDNGVVLELTSRGSHCKTNGHVAR
                     MAQQSGALMVVNTDAHSPGDLIDLATATQIALAAGLTREQAELALIETPKAIIKRRWR
                     N"
     gene            complement(17271..17873)
                     /gene="hisIE"
                     /locus_tag="PKM11_04405"
     CDS             complement(17271..17873)
                     /gene="hisIE"
                     /locus_tag="PKM11_04405"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HNX47782.1"
                     /translation="MSSPKFGEDGLIPVIVQDQETNEVLMMAYANEQAYRDMLRTGFT
                     HFYSRSRKEQWKKGETSGHVQEIVSMQLDCDNDTLLVRVKQTGVACHLERMSCFDEVV
                     YGDIEGTMAVLPQLLQVIRDRKANPKDDSYTCKLFADENKRLKKVVEEAGEVLLAAKD
                     HQAAEQSWEVADLIYHLMVAVEGMEVEWTDVYRKLAERRK"
     gene            complement(17870..18625)
                     /gene="hisF"
                     /locus_tag="PKM11_04410"
     CDS             complement(17870..18625)
                     /gene="hisF"
                     /locus_tag="PKM11_04410"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HNX47783.1"
                     /translation="MSLTKRIIPCLDVKNGAVVKGIKFLDLKDVGYPPEMAETYERQG
                     ADEIVFLDISASAEGRKTLLGIVEETAKRLFVPLTVGGGIREKEDMRAALNAGADKVS
                     VNTVAVQRPDIISECAKDFGSQCVVVAIDAKRQGGDWTVYTHGGRKDAKMDMVQWARK
                     VEDLGAGEILLTSMDADGTKDGYDIAMTKLVAEAVNIPVIASGGCGSPKHILDVLKET
                     KAEAALAASIFHYGQWTVRDVKAYLKENGVEVR"
     gene            complement(18622..19173)
                     /locus_tag="PKM11_04415"
     CDS             complement(18622..19173)
                     /locus_tag="PKM11_04415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase"
                     /protein_id="HNX47784.1"
                     /translation="MDRKTEVVRKTRETEVRLKLDLDGEGVTKVECEEQFLRHMVETM
                     GRYANFDLTLEASGDDVHHLVEDVAIVLGKTFKQCLGETPIERTAFSLIPMDDALVQV
                     AVDIIERPYADVDCPDDLYAHFFRSFAMSSGITLHIMVIRGYDQHHIVEASFKALGKA
                     LRSAVLPRLSELSTKDRPKVSKG"
     assembly_gap    19253..19352
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<19353..19735)
                     /locus_tag="PKM11_04420"
     CDS             complement(<19353..19735)
                     /locus_tag="PKM11_04420"
                     /inference="COORDINATES: protein motif:HMM:NF013168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HisA/HisF-related TIM barrel protein"
                     /protein_id="HNX47785.1"
                     /translation="MRIIPAVDILDHRVVQLVGGVPGTEQVTLPDPLTVARDWESKGA
                     KRLHIIDLDSALGKGHNAQVIRSIIERSDVPVQVGGGIRSTEVAEYFLDCGADRVIAG
                     TKGLKDPAWLRTMSLKYPKRMVLAL"
     gene            complement(19732..20331)
                     /gene="hisH"
                     /locus_tag="PKM11_04425"
     CDS             complement(19732..20331)
                     /gene="hisH"
                     /locus_tag="PKM11_04425"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HNX47786.1"
                     /translation="MPLKVSLADYGVGNLHSIRKALENCGASVTVVEDMSLLRESECI
                     VLPGVGAFDRTMERLLPYKDEIVQRLNEGVPCLGICIGMQILFQNSAEGDGPGLGFLH
                     GSVVRLEAPRIPHMGWNTVETDDDIMNGVDDTHFYFAHSFHGRPEDRSDVGHTDYFGR
                     IPTLFHKSNTYGTQFHPEKSSFAGMAFLNNFVRFAEERT"
     gene            complement(20322..21374)
                     /gene="hisC"
                     /locus_tag="PKM11_04430"
     CDS             complement(20322..21374)
                     /gene="hisC"
                     /locus_tag="PKM11_04430"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HNX47787.1"
                     /translation="MNKDWIRSTCRDLQLYYNPNVGDKLRMDTSTNALGANPAGQREL
                     VECTKLNVGQYPNTYGDKLREELAKLYGMKADNFVVGNGSDEVLDIIMKTFMEPGETV
                     ITAHPAYVLHSFFVKINGGRTVTVDLNDDFQLDVDKINSTPGKVVLLCTPNNPTANTF
                     RVDDLKAVIEGADRPVIVDEAYGEYTNDTFLPLVDRYDNLMVTRTFSKAYGLAGMRIG
                     YLAAGIEMAEALQKVKIPYSLNMIGERVAIAALRDREFLERSVRLVNQERPFLSKGLS
                     DLGFQVFPSEANYILFRPEMPSDVLTKKLSEKGVLVRDFGKVRRLENCIRTTIGTREM
                     NTVLLDRMREVLRECR"
     gene            complement(21385..22248)
                     /gene="hisG"
                     /locus_tag="PKM11_04435"
     CDS             complement(21385..22248)
                     /gene="hisG"
                     /locus_tag="PKM11_04435"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: protein motif:HMM:TIGR00070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HNX47788.1"
                     /translation="MTLRLAIPNKGRLSERSIEILKQAGLEIENGDERRLYANVKRQD
                     LAVMFLRASDIVKFVHKGAVDVGITGYDLVLESGLDVIVPYHLNFGRCRLSVAVPDTM
                     DVKRPEDLPDGLVVATSFPNLTKQYFEKLGKKVDITIISGAAEIAPILGVADIIVDLV
                     SSGSTLKMNHLRELAVITESQAVVIANRKAYEGCEQQVQEIISAMLSVTEAENKKYLM
                     ADVPKSSLEEVKKAFPGIAGPTIMNIIGRDDVVAVHVVIEKTDAFDAINKLKRMGATG
                     ILLTPIDRMVP"
     gene            22414..23241
                     /locus_tag="PKM11_04440"
     CDS             22414..23241
                     /locus_tag="PKM11_04440"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HNX47789.1"
                     /translation="MRRSMAAEEWQDIWEMANSHSPYRTFPMDRQRLVQHWNEVSKDY
                     DSESMSLIDERIWGLLEDMSVVPGGNALDIGCGTGSLTSMLASECSHVLGLDISPGML
                     SVAKERCSSLNNVELLCQGWEEFLPERRFDLVFSSFCPAVDDVRSVMRMDAMSDGTCC
                     IVSLGGSSGDRLAFDIWEELGHPGMSMEGFDPIFPYRILKEMDRRPSLRRFDVHEETE
                     MAAEDMVRHLVRYFSLFHEVDERVKKVIADSVQRRSDGRRFTLREDRTVSVLKWTAI"
     gene            complement(23238..23957)
                     /locus_tag="PKM11_04445"
     CDS             complement(23238..23957)
                     /locus_tag="PKM11_04445"
                     /inference="COORDINATES: protein motif:HMM:NF003324.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0280 family protein"
                     /protein_id="HNX47790.1"
                     /translation="MRRLFQFKETAATIEADEEYLPLAEDALLKAREQVEAYIAKDPY
                     FKTTFEPYAVRSDMGDVVKNMCNAAQKADVGPMAAVAGAISQKAVRTMVDQGCKHCLV
                     DNGGDIAMRTNRTITVGLYAGERTPNYLALEVPATKGMLGICTSSGTVGPSISFGRAD
                     LATVISEDVALADACATKLGNLITEDDLTLMDRSIREVLSIKGVKGALVMINGKLGIG
                     GDVPRLVRCDVPPDRITRIRF"
     gene            complement(23954..24358)
                     /locus_tag="PKM11_04450"
     CDS             complement(23954..24358)
                     /locus_tag="PKM11_04450"
                     /inference="COORDINATES: protein motif:HMM:NF020940.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX47791.1"
                     /translation="MAKKKFLLGFSPDIVNEPIVYRLVKDYDLKINILRAEVREMGGR
                     LLMEVEGKAFNIKEAARYLGEAKVDVQELITYVEKNEDRCTHCGMCISICPVEALTMD
                     RPSWKVRYDSEKCIACGMCIDACPPGAMKFRI"
     gene            complement(24358..25524)
                     /locus_tag="PKM11_04455"
     CDS             complement(24358..25524)
                     /locus_tag="PKM11_04455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine biosynthesis protein"
                     /protein_id="HNX47792.1"
                     /translation="MKRTVAEINQRIKDGDVVVMTAEEVISFVQSEGVERAAKEVDVV
                     TTGTFGAMCSSGAFLNFGHSEPPIRMQKVTLNDVPAYGGIAAVDAYIGATELKLDDHS
                     GYGGAHVIEELISGKAVRLKATSDGTDCYPRKDIDTFVSLNTINQAYLFNPRNVYQNY
                     AAGTNSSDRTLYTYMGKLLSNYGNITYSSAGQLSPLLNDPSLRTIGIGTRIFLGGGVG
                     YVAWEGTQFKTNVETQFGAPMGGARNLATIGDMRGMSPEFVRALSLPGYGVSLALGIG
                     IPIPILDEDVLRATAISDEQLFAPLIDYSVQSRNRKPLKHFSYAELRSGRVELFGKEV
                     RTSSLSSYLKARQIAEALSERIESGEFLLTEPVASLPADRSMGTLEVRSKEEAV"
     gene            complement(25536..26597)
                     /gene="asd"
                     /locus_tag="PKM11_04460"
     CDS             complement(25536..26597)
                     /gene="asd"
                     /locus_tag="PKM11_04460"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HNX47793.1"
                     /translation="MKKVQVAVLGATGMIGQRFVQLLEDHPYFEIGGLYASERSEGKS
                     LGEVMKLKGIRFQEETLATKIESLDPKAVAKRNRLAFSGLPTEVAKDTESSLAELGVA
                     VFSNAASHRMGADVPLLIPEVNPDHLELVRKQSTFGNGGFIVTNANCSTTGLAVPLQA
                     IYKKFGLKACYVSTYQAVSGAGYPGVPSLDILGNVVPFIKNEEEKMEEEIHKMLGAYK
                     NGKLKFAEFDMVASCARVPVIDGHLESAVLKLEKDADAEAIIKALDAFVSEPQKLKLP
                     TAPVQPIIVRREENRPQPAADALAGEPERARGMAVSVGRVRESKGYIKFWLLSHNTLR
                     GGAGGSVLNAELAVAKKFL"
     gene            complement(26594..27670)
                     /locus_tag="PKM11_04465"
     CDS             complement(26594..27670)
                     /locus_tag="PKM11_04465"
                     /inference="COORDINATES: protein motif:HMM:NF014234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004665 - prephenate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase/arogenate dehydrogenase
                     family protein"
                     /protein_id="HNX47794.1"
                     /translation="MTDSVEGIRWKIEEIDNEILDLIKKRMNIAVDMGHHKVDKAMPV
                     RDMRVEDQVRNRYLARAKEVGISDAAAVELSALLVRESVEAQARLPRPMKPRQVLVVG
                     GGGAMGQWLCRFFASRGHGVKVFDDLPGGEFQNVKLEEGVKEADVIAVSSHISATADM
                     LRKIFALRPKGLIFDIASVKSPIMDVLKEGADQGLLVCSIHPMFGPSASFIFARNLIV
                     CNCGSDIAVNKFMPLLNGTGANVIEMPVEDHDKIISVVLGMSHALNLAFFGALKESGF
                     TYEELRKVSSTTFERQMNTSGSVARESPNLYYEIQHLNPHNSEMLDKLIDALREVQLA
                     GSDEDRSHMIRLMHEGRKYFEVKQ"
     gene            complement(27663..28736)
                     /gene="aroC"
                     /locus_tag="PKM11_04470"
     CDS             complement(27663..28736)
                     /gene="aroC"
                     /locus_tag="PKM11_04470"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HNX47795.1"
                     /translation="MNTIGSELRLTLFGASHGPCVGAVLDGVPPGMMIDLGRVQSEVD
                     LRKPRTEIGTPRQEEDLVEIVSGIVEGKSTGGPITLMVMNRDTDSKKYDRFKSVPRPG
                     HADLTARSKYSECVDLRGGGQFSGRMTVAIVAAGAIAKMLLEERGIRVAAFARQIGRV
                     RDEEERDVTSGVLSRSNEVRAATDELAEAMRSEILAAKDDGDSVGGVVECIVDGIPIG
                     LGEPFFDTVEGELSKMMFAVPGVKGVEFGAGFAAAGMRGSQHNDPFILVDGKVRTSKN
                     DAGGILGGITNGMPIVFRVAIKPTASIARGQRSLDVKSGRQTDLKIEGRHDPCIAPRA
                     VPVVEAAAALVLADLSMRGGTVD"
     gene            complement(28733..29998)
                     /gene="aroA"
                     /locus_tag="PKM11_04475"
     CDS             complement(28733..29998)
                     /gene="aroA"
                     /locus_tag="PKM11_04475"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HNX47796.1"
                     /translation="MRLRVVPSNAEGIVLSSPSKSYTHRAMTLALLADGESVLRRPLL
                     GEDTLATLDAVTAFGGKVARNDALHITGGHLRCPEKIIDVKNSGTTIRLMAGVASLLS
                     CETTLTGDDSIRRRPMQPLIDALGMMGVRCESTRGNGMAPLIVRGPNLGKRTEIRGDV
                     SSQFISSLLISSAVKEVDTEIVLTTPLKSKPYVDITMEMMARFGANCRSTEQGFLVRG
                     GQRYLPQDYTVPGDFSSAAFPLAAGALTGKVTVRNLDPQDAQGDRAFLKILESLGAKV
                     EWAGDSITCSSAELVATDIGLGDAPDLFPMAAVMCAFAKGESRIYDAAHVRLKESDRI
                     SATTLFLKDMGADIRETEDGCVIRGGRPLHGTHVNSFNDHRILMAAAVAALRASGETI
                     IGDGDCHRISYPDFVSDMLSLGAKMEMIP"
     gene            complement(30001..30834)
                     /locus_tag="PKM11_04480"
     CDS             complement(30001..30834)
                     /locus_tag="PKM11_04480"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: protein motif:HMM:TIGR01920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HNX47797.1"
                     /translation="MKGRGEAMGAVTIVNAIAAGKGCAVGVDLRTWAEVALIPGEGVE
                     VHLEGLPDEPSKLVQMCVQAVLERFSLRKRAIVRTGSQIPVSRGLKSSSAAANAVILA
                     TLDALKMEMPAIDILKMNAEVSIGAGVSVTGALDDAAASLLGGIVFTDNHARTLLRRE
                     RFDLSDQVVIAVPERMIRKTNLPKERIALYHPLAEEAFRLAWNGEYVKAMTLNSLIYG
                     AALGLDQELSIKALGAGAIASGISGTGPAVASFVDAGTERTVAEALGKDAIIAKVYQG
                     V"
     gene            complement(30831..>31673)
                     /gene="aroE"
                     /locus_tag="PKM11_04485"
     CDS             complement(30831..>31673)
                     /gene="aroE"
                     /locus_tag="PKM11_04485"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: protein motif:HMM:NF001319.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HNX47798.1"
                     /translation="QLDLETAKWLGKEPIVTGIVGYPLDHTLSPVMHNAAFRSAAVRG
                     MYLKWVTMVDELEDFLDVVATLGIKGFNVTIPHKESIVPLLDRVDPVAERIGAVNTVV
                     NEEGSLVGRNTDVIGVERTFEHHNVDVKGKTALVLGAGGASRSVLSFLVSKGASVDLT
                     NRTMGKAESLAKLFGANAVTNRVAEEKKYDVIVNCTPLGMKGFPQEMSISPHVLREGQ
                     FVMDTVYNPPVTPLLAEASRKNAIAVNGKDMLIYQALASFEMWTGKAVEHEVMEKAFR
                     EALP"
BASE COUNT         5781 a         9738 c         9408 g         6546 t
ORIGIN      
        1 ttctctggta catacgtata cctagagcac tgggcgtcat cggcgtgggc gtcgggctgt
       61 ctgtcgccgg ggcggtcatg caggcgctca tccgtaaccc gttggtcgac ccatacataa
      121 ccggtgtctc ctccggagcg gcgctgggag tgaccaccgc ggtgctggcg ggagtgacca
      181 tcggggggct cgggatattc gtaactccga tcatggcctt catcggggct gtgttggcct
      241 tcttgttcac catgcttctg gccgaggctg ccggcgggcg ctcgatcagt tacgttctcg
      301 gcggggtgat cgtggggatc gccctgcagt cggggaccac catcctgatg tacttcaacg
      361 ccgaccggct acacagcgtg ctgtactggc tgttcggttc gttctccact ctcaactggc
      421 agtcgaccac catcatcgtc ctctgcgttt ccgtgctagc ggcgataatg ctgctctacg
      481 ccaaggagtt caacgtcatc ctcctggggg acgagcaggc ccagcagctg ggtatgaatg
      541 tcaagcgctt caagaccggc atgttcgtac tggtgtccgc cctgaccgcg gtgtgcgtgg
      601 ccttcaccgg gatcatcggt ttcgtcggcc tcatcgtgcc tcacctggta cgtatgctca
      661 taggcggcga tcatcggctg ctccttccgg cctccatggt ggtcggggca aacattcttt
      721 tgattgctga cattgtatgt aagaccgcgg tggctccctc tgagctgccg gtcggtgcca
      781 taatatcgat catcggagct ccgttcttcg ggtacctgat gatcaggatg ggcaaggaat
      841 atgtcatgtg atgaggagct gacggtgaag gtcgacaacc tatccttcag ctatggtgcc
      901 aagaggaacc tttgcgccaa aacgctcaag ggcatcacca tcgacgccaa gaagggccag
      961 ctcatcggga taatgggtcc gaacggttgt ggtaagacca ccttcatgcg ctgcatcaac
     1021 aaggtcctta aaccgcagga aggcgccata tacattgacg gcaaggacct ggaccgcctg
     1081 aagatgatgg aggtggccaa gatctgcgcc aacatcccgg cggacgtccc ggacgatttc
     1141 catctgtccg tggaggagtt cgtggcccta ggccgctacc cgttcgtcac cggcatctgg
     1201 tgggaggggg ccaaggacga ggagctggtg cgggacgcca tgaaagccta tcacgtcacg
     1261 catctgaagg acaggaagct cggcgagctc agcagcgggg agaaggcccg ggtgctattg
     1321 gcgaaaggcg ccgtgcagca gccgaagatc cttcttgccg atgagccaag cgcgcatctc
     1381 gacctgaagt tcaaactgca ggtcatgcag gccttgaagg acctctcccg ccaaggtgta
     1441 acggtcatca ccgcctcgca cgacatcaac ctgatcgcta agtacgccga tctggtcata
     1501 atcataagcg agggcgggat agtgagctac ggacctccgg cggaggtcat caacgaggat
     1561 atcatccgcg ccgtgtacgg tgtggaagtt tcgatcataa gggataacgg cgaactgtac
     1621 gtcatcccgc tgagaccggc ggaaccggag aagggcgacg atgaagatcc aagaccttgt
     1681 gaaaaaggaa ttgttgccga ttaagaggcc tgtgcacgga ggccagggct ggaagcttcc
     1741 cggcgtggag gacttcagcc acaacctgaa cccgtacggg cctccagcgg agctgccgcg
     1801 actggtggcg gaagcttcgg agcagttaag ccattatccg gacgatacgg ccacggagtt
     1861 cagggaggcg gtggccactc tgcacaacgt ttggccggag aacgtgatcg ctggcgccgg
     1921 ctcggccgaa cttatacgcc tgttccctga ggtgttcatg tcccgcaagg cccgggtgat
     1981 catcccccga ccgaccttct cggaatactc gcacgcctgc cgtatgcagg gggctaacat
     2041 actggacgtt ccgcttgtcg aaggggaagg cttccgcctg gacatgaacg ccattcgcga
     2101 aaagttaccg ctagccaggg cgttgtacat ctgcaatccc aacaacccta ccggtacggt
     2161 cgaaactaaa agacgcatca tggaactggt ggacgagtgc gagtcgaccg gtaaactggt
     2221 cttcctggac gagacgctgc tggacctcgt cgacgatcac gaaagcattt catgcatgtc
     2281 tgaggtgcag agccacgaaa atctgttcat catctcctct ttgacgaaat cgttcgccat
     2341 ccccggaatg agggtcggtt acggcgtggg cggcgtggag atcgtggaca tgatggaacg
     2401 agcccggctc tcctggaacc tgggggtcat agagcagtac gtcggcgctc gactgctgcg
     2461 cgaccatcag gaccacgtgc gcaaggcggc gcagatgatg gcctccgagc gcgctcgcat
     2521 aaagaaggcc gtggacagca ccgggctgct gtcgccgctt ccggaccagt gcttcttctt
     2581 cttcacccgg gtggccgatc ccaagaggtc cggccaggac gtggtggagc acctcctgcc
     2641 ccgcaaggtg ctggtaaggg attgttcgac gttcggacga ccgttcgaca ggttcatccg
     2701 cttcagcgtg aagacgccgg agaagaacga tatgctgatc gccgcgatcg aagatacggc
     2761 cagggagatc cgcaacacag cgttcggggc gaggatgcat gtttgagctc gttccctacg
     2821 cgctcctgac gatcatcatc gccctgctca tcgatcgttt cataggcgaa ccgccgaact
     2881 ccctgcatcc ggtggtctgg atgggcaagg tcatctcgtt cttcgatgaa cggatagctc
     2941 gcgggcatcc ccgccgggag cggttgttcg gggcattgat ggccttggcg gtcatactga
     3001 tgttctcgat cgcggtcctg ctgctgatgg cactggtccg ggattccctg ggattactgg
     3061 tctgggccgt ggtcggtgga atcctattga agaccatgtt cgccatgtcg gcgatgggca
     3121 agcacaccga accggtgcgc caggcgctct tggccggcga tctggaactg ggaaggcaga
     3181 aggcggccat gatggtctcc cgggacgtga gccagctgga taaggaacac gtcatctcct
     3241 gcgcggcgga gagcgcggca gagaacacgg tggacagtat cttctccccg ctgttctact
     3301 tcggtctgct ggggctgccg gccgcggtcg cctaccgggt ctcgaacacc ctggacgcca
     3361 tggtcggcta tctggacgac aagcaccgct acgtagggtg gttctcggcc aagctggacg
     3421 atggcacgaa cttcgtcatg gccagggcgg cggtgccgtt catactgctg gccttgttca
     3481 ttctgggcaa ggactggaac gccggctgga aggcctcgaa gaaatttcac gatcagacgc
     3541 tgtcgccgaa caagggctgg cacatgtccg ccttcgccgg cggattgggg atccgtttcg
     3601 agaagatcgg ctggtacgtc atgggtgacg gaccgttgcc gtcggacccc gaggtactgc
     3661 gggacaccat aaaggtcatg accatggcct cgtatctctt cctgctcacg gtggtcatac
     3721 cgctctacct tctggtcgga gcggaggtgc aggtgttcgt ggaggacatc ctgctaggtt
     3781 tgataggtgt ttgagatgaa gctcagcgaa gtgcggatag agaaaggcgc ggtggacggg
     3841 cacaagtacg tggctatacg gttaccgcgt cgcctgcgca ccttggcgtc caccatattg
     3901 aacggtggac tgggggagac cgattccgtg ctcatgctac aggtctcgct gcactacgat
     3961 cacgctgatc cggtggagca cctgcgctcc ctgctgcccc gattgggcct accatcggac
     4021 acggtgtgct tcatgaccgc cgccgagctg gacaaggcgt tctgctcgaa aggattggaa
     4081 cagaacgggt cggaggcgtt ggccttcgtg agcgccggca tatccaacgc catccgggcc
     4141 ggcgaatcgt cccgcgaggg aagcgtgcct catcgccagg tggggaccat aaacgtcatg
     4201 gtggtgacgg acgagccgct ggacgactgc gccttggcga acgcgatcat gacggtgacg
     4261 gaagcgaagg ccgccgcgct gcaggaccat catatacccg gaacgggaac gacgagcgat
     4321 gccgtgctgg tcatgtgccc ttcggacggc gagagatgtt tgtggtccgg aagctcatcc
     4381 gatcacggca tagccatggc ggtggcggta cgttcggccc taggggaatc gatagcccgg
     4441 tggaaagggg cgaacgggga ctccgttcac ttcctcaggc atctagcgat acgcggcatc
     4501 acctacgatg acatgtggaa cgcggtcaag gagatgaacg ccctggaccc ggcctgggac
     4561 gaggcggaga tacggaagag gttcgagaga aagctcgaga tgttggccaa ggacatcaac
     4621 gtgaacgccc tgctcacggc ggccatcctc ctggaggaaa aggggcgtta tgggcagctg
     4681 tacggtctca acgaggaaaa gtaccaggag gacccggtgc accttctggc ggacgagctg
     4741 ctgggcatcg ctctggcgga atacataggc ggttccaagt gcgtcttcga gtacatccgc
     4801 tacgacaaga agaagcctgg gatcctatcc aaactgggac cgttcatgga tgacatcgtg
     4861 gcctcgctca tcggggccac catgtctacg atatactcgg agatactgga gggagaagga
     4921 cggctgtcct aggcgcgctg aaggccgctc tgaccatgtt cacggtcctn nnnnnnnnnn
     4981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnna ctggccaggc cgagctgctc ttctttccgc
     5101 tgatagccga gataatgaac aagaacgcca tggtgttctg cgcctacggt ggcaaggccc
     5161 gggaggggct cggcaactcg ttcgtctcca ataccaaggg caagcaggcg cttctctcgc
     5221 tcgtcctgtc cgttttgctg gccttcggag cgatactgtt ggtatgtctc cctactggtt
     5281 actggcatgt tgacaagatc gccctgttca cggtcgctgg cggtctggta agtgccatcg
     5341 tcggcctgct ggtcggtcgc gtggccatga agaacttcgg ggcggtcaac ggcgacgtca
     5401 tgggggccac gaacgagata tcccgtccag tggtgctgat cgccatgctt ctgctggtgg
     5461 cactatgagc gtcgccgcac tgataaccgc cggagggcgc gggaccagga tcaaggagat
     5521 gggcgtcgag aaaccgatgg tccaattgca ccggcggcct atgatcgacc acgtcctgga
     5581 gcagatgatg ctggtcgatg agatatcatc cgtttacgtt tccgttagcg acaacgtccc
     5641 gaacacccgc cgccatctgg agcagatggg cgtcaatctc ctggagacct ccggcacgga
     5701 atactgccac gatcttatcc aggcggcgga ggacatcgcc gaggaccaca tattcatctg
     5761 cccggccgac ctgccgttgc tgcgggcgga actggtctcc gacgtggtca gggagttcct
     5821 gaaaagaaag gagcaatccc tcaccgtcgg tatccctctg gagaaggccc tggagttcgg
     5881 cgtggacgtt accttctacg agaacgtgaa cggccagccg ttaatgcctt gcggggtcag
     5941 cgtagtggac cggaagagaa tgctcacccg ggaattcctt cccggaagct attacgtggc
     6001 ggagacgccg gaggtggtcg tcaacgtcaa caccatggcc gacctgaaga aggccgaaaa
     6061 ggagctgcac cggcggttca cttgcccatg atcctcatga gctggacgta gttcttctcg
     6121 acctgcgaga gcatctgctc cttgccgatc ttgccctgtg atgccaggaa gacggcgacg
     6181 gaaattcctc cggcccccac accttccttt accagtcctt tctcgtagac gttcagcccg
     6241 tcgtgcttgg acggtccgaa gtccaggtcc gcggctagta tcgggacctt cccgatctgc
     6301 ttgactatcg accgaacgtc cgaggaacgg tcgttcacga tccacttggt ggttcccaag
     6361 gcgatgttcg atagcacgtt gggcgccagc cccttcacga tggccatgac ggccgccatc
     6421 tgcgttcctc cggccattat gaccggtatg ctctccgccg ccccggccac cacgccggcc
     6481 gccgcgggca tcatgggatc gccgaccgcc tgcgccgcct tcaacgggtc ggccttcatc
     6541 tccgccatgc tgaaagggga tttggagatg ccctcttgaa cgatcttctc cttgagggaa
     6601 tgaggattct ctatcatgct gctggatact ttgccttggc cgtcgtatcc catggccatg
     6661 agtaccgcca gggcggtggt cgttccgccg gctatgctct cgccgataac caagtactcg
     6721 ctgttcttag cgagttcccg gcccagcagg acgccgttct catacacccg gcgagggtcc
     6781 ttgagcgcct ttccggtgcg gatgtcctcg cccgcggagc cttccagctc aaaatatggt
     6841 gtgtgcggtc tgacattgac gccgccgttg atggcaaaag ttggcatcga caccagttgt
     6901 aaagcgctca tggtgatgat gcctggagta ggaaccccgg tcggagtgac cggaacgccg
     6961 tcgatgcatt tgcatcggcc gtagtagaga agttccacgt ctgccgcggg ggtgaaatcg
     7021 gtgatggccg gcaccgctcc ggcggcggac acgccaggga tcttggccgt ctcggtgttc
     7081 ccgatgacca cggcgtaggt ggggcgcttg ccccagacct tggcaacaaa gttccttccc
     7141 gcctgctcct ccaacgcgta aatgatgtcc gctttgtgca tgataaggac ctctggatat
     7201 gacgcaacta ttgactggtt gtatcatcca actcaacgcg aagaagatat ttaacacatt
     7261 gccgagggta aaaaaatatt aaaggatcag tcttcaaaga tggtgtccag cagagttccc
     7321 agggggacgt tctctccgtc gttctcgtgg aagcccttct ttcccctccc tttccgcagg
     7381 cctccgcata cggcgtacgg aaccttcatg cgcatatgct ccccggtgac cgaggaggcg
     7441 ccgtggtcga tgagcaaggc cacccggcat tcctggaagc gcttctcgta acgcgatagc
     7501 tcccgatcga tctcctcgat cagcatcagc ttgttcttgg ggttgcactt gtggctgatg
     7561 tcgtccgtct cctcgatgtg caggaacacg tcattcttat ccaggacctg ggcggccagc
     7621 ttgatgccct ccttgaatcc gggaacgcgc accgtctcca tgcccaggaa tttgccgacg
     7681 cccagggcgg aggggctttt cgatatgacc gtgaggtcgg ggaccttgga tatctccctg
     7741 cgaacgtcca ccgccacctt tccaagccca ccgccccagg gtaggagcgc tataccgctg
     7801 gtgctctccc gcacgccctt ggcgaagtcc aggaaggggc cgaggtcctc ggagcttatt
     7861 tgagcgggac cgggcggctt aggcaggtca agtatctcat cgcccttgat ggtcagcacg
     7921 cccttgccac catggtacgc caggatcttg gggtccatgt ccttgagctt ggaacggttc
     7981 ttgattatgg cccgctgcag gaacatctcc tcgtcgcagg tgatgttgta gtaccattcc
     8041 acgttatgat cgtgcacttt ggccggggtc attcggtaag cgacccgccc ttcgccgata
     8101 ggcagctcca agccaaacgc ttcgatcacc ccgcgcggca cgtcgtaagg ttttccagtg
     8161 agcagctcca gaaggaacgt gtgagtgtaa tccttcccgt cggtggtgcc gaccttcccg
     8221 tcacgtgcca cgcagtccat gaaatccttg cgggccgcct ccaggggggt gcggttcttg
     8281 aatattgaga tgcgctcgtc ggccgcgccg tccagtagga tgatcagctt tctcatttaa
     8341 caggcctgac gcttcggaat ggccttgagc atataatatc tgttggtcat atcgtccaac
     8401 tcggggcatc catatatgcc tcgaagctca tcctgcggac atggcggtgt ccgatgacca
     8461 ggggcgcgag cgtcggttcg ggcttccccc ggtcgtcggg aacgctccca cggtgcttat
     8521 ccttgggacc atcccgagtg tgctatcctc ccgaaaaggt cagtattacg gcaatccact
     8581 gaaccacttc tggcggttga tgggagaagc gctcgaggag acgatgcccg atgattatcg
     8641 cgccaggtgc gaaacgctca ccaggaacgg gatcgccgtc tgggacgtgc tggccgaatg
     8701 tgacatccgg ggcagcgggg accactccat cgcgaatcca gttcctaacg atatcttggg
     8761 cttcctggag gggaacagga gcatccgcca cgttttcatc aacggcaagg ccgcccatag
     8821 gttctatctg aaatttctcg aagatgcgtt cgctggccag gtgacggtgc tgccctcgtc
     8881 ctccccggcc aacgccatga gaagggcgga taggcgcgag aaatgggtgg agatcggaaa
     8941 ggtccttcgt tcctagttcc cggttcgcga cagcgctacc gcgcattgac cggtcgatat
     9001 gcatccatca ccgttaggcg tgaggtcatg acagacgaac ttcaggccgc gcgcctccac
     9061 caggtccttg gtccaggtgg atatggctcg attgtagctc accccgccgc ttaggcctat
     9121 gtgctcgatc ccctcgtcct ccgccttctc tgacgcgatg tccaccagcc cgcgcaccat
     9181 ggcgtaggtc atgcttccgg ccctatcggc ctggttgccg cgcacgttca tcatttgtcg
     9241 gaacatggct ggggtgtcga tgacgttccc gtgacgaacg gtcggcacca ggtccaggtt
     9301 tcgggccaga ttgaggtatc tctccagctt catggccggc tcgccatcgt agctgcggta
     9361 ctggcagatg ttcagatagc aggagatgcc gtccagcacc cggccgaacg aggtgctcgt
     9421 tccggagcgg ggcatcatct tgcggaacag ctccctctcg ccctcgttga agtagtcgag
     9481 cccaccgccg ctcatctccg ccagggcgaa ggctatcctc cgaacgtcgt acacggcctt
     9541 ctccccgccc agcaacggca cttccttcag atggcccacc cggcggtatt ccttcaagtt
     9601 ggagatcagc acctctccgc cccacgccac gccgtcatca ccgtagccgg tgccgtcaac
     9661 ggttatggcc accatatcgt ccagtttaga ttctacgagc agagccgcgg cgtgggcgtg
     9721 atgatgctgt acctcgaccg gctcgatgcc gctctcctcc gcccaccgtt tcgcaaggcg
     9781 cctggtggaa tgaccggggt gaaggtccat cccgatggcg tccaatcggt ccgcgccaag
     9841 cagccgcctc aggtacttca ggctctcctc caggaactcc agcactcctg gtgacgtggc
     9901 gtcgccgatg tactgggtgg cgtaaagccg ccggtcgaac gacagggccc ctgccagacc
     9961 ttcctgggca ccgacaccta tggctacgcc tttcagcgga aattcgatgt gcgagggtat
    10021 gtgccctctc gatttgcgaa tatagtaggt cttgtccagg aacgatcgga ccacggaatc
    10081 gtcgcaacgg ttggcgatgt cccgatcatg catcaggtac atgtcagcgc ctagggtcag
    10141 ggcatccgat tcccgcagca ccatcggttc gccagggacg ttcgccgagg tcatgaccag
    10201 ggcgtcctcc tcgaggtgat ggaacagcag gtgctgcatt gacgtgtacg ggaggaaaac
    10261 cccgatggtg tccagaccgg gcgccaccag ttcagtgatt tcgttatcga ccttaggcac
    10321 cagaacgatc ggccggtgac tggaggtgag caacttgaca tcctgatcgg aaggtcttcc
    10381 gtaacgttcc agggccttca ggtcccggac catgatggcg aacggcttct ccttgcggcg
    10441 gtaccactcg cgcatgtgcg acagttggtc cagagcgcag cacaggtgca tcccgcccca
    10501 gctcttggcc acgccgatct tgccgtcctg cagcttcgaa gcgaacctgg ctatcggccg
    10561 ctcgtagtct cgctctccgt cacggtctaa tagatagtag cgcgggccgc agaccggaca
    10621 ggtgaccgtt tgatgatgga agcgccggtc gtccgggtct ccgtactcct gctggcactg
    10681 ggggcagagg gggaacgggc gcatggtggt cttttcacgg tcgtacggaa gatcttcgat
    10741 gaccgtgaag cgggcgccgc agtcggtgca attggtgaac gggtaaagat agcgcctatc
    10801 ggagggatcg aacatctcct ttaggcagcg atcgcagacg gcggtgtcgt taggaatccc
    10861 gacgcccccg atgccttgct ggctagggag tatcttaaat cccatggtcc tcagctcggg
    10921 ttcgggaagt ccaggggaga tgaccacctc atccagatgg gccagcggcg gtagggcttg
    10981 tttcagccgg cgcacgaact cctcggcgtc cccgtccatc tcgatgacca cattggaacc
    11041 gttgttctgc acgtaaccgt ggaggcccat ggacctcgcc aggcggtgga ccgtcggccg
    11101 aaaaccgacc ccctggacca cgcctcgcac ggttatccgc atgcctcttt ccatccagac
    11161 cccgatatat attccttgtc agtccctgcc gcacgagaca taaatatccg tattccgttc
    11221 cgaaggagga tagtatgagc gacgtaccag agggactcca ctataccaag gaccacgaat
    11281 gggctaaggt cgacggcgat atcgtcacgt tgggaatcac cgaccatgcc caggatgagc
    11341 tcaccgagtt cgtctacgtc caactgccga agaagggaac caagctcggc aagggggacg
    11401 ttctggccgt ggtggagagc gtcaagaaca ccgctgacgt ctacgcggcc gtgtccggtg
    11461 aggtcatcga tgtgaacggg ccgttggacg acgatccctc gcagataaac aagtccccct
    11521 acggcagcgg ctggatcgcc aagatcaaga tgtccgataa aggcgaacta aaaaaactga
    11581 tggacgcctc cgcctaccgt aagcatatcg gcgagtgagc tagtaatcca gatagatgtt
    11641 atgggcctgg cactccgccc gtaaacgttc cacgaaggcg tcttcgtcct ttaacatctc
    11701 cttcaccgcc gcccaggtct gcgtgcagtc cttgtattcc actccgacca tctcgtggat
    11761 gatcatgtcg acccgcttgc gattgtcgat gtcgatctgc agcccggccc ttaggaacac
    11821 agggtcgaga tgccgaaaat agcaggtcat taggaatagt atgtcattga ttaaaataaa
    11881 aatgtttcag tcctgttccg cgaaccctta ataaggaagt gccggcaatc atgccttatg
    11941 aaagacaagc tccaggaggg cgacacctcc ccggatttct cgctgccaga tcaggacggt
    12001 aggaccgtca gttccagcga catcaaggga aggaaggccc tggtcctcta cttctacccg
    12061 gccgacttca ccaaggtgtg caccatggag gccgtggcgt tccggcagat gcacgagcag
    12121 ttccaggccg ccggggccga gatcatcggc gtttcgtcgg atgacgtcaa gacccacaag
    12181 gagttcgcgg tggagcacga gctgacgttc accctgctca gcgatgagaa ggaggggctg
    12241 aggaaggcct tcggcgctta tggcatcggc ggaactccgg cacgcacgac ctacgtcatc
    12301 gaccgggatt ggaagatacg catggtctac aattccccgc tgcgctccaa ggagcacgct
    12361 gaggaggcca tgaaggccat ccgagcgctc tgatcaagcc ccagcgtcgg ccagaacgct
    12421 gccgcaggcg cacttcttcc tttcctccgg gatcttgggg atggtggtgg agagcagttt
    12481 gcgtatcttg tccatgttct cggccatggt gcgcaagatg gtggcggtat ccaccggatg
    12541 atcggcccac acatcgtaat cggtgatcat ggccaggctg gtatagcaca tctccatctc
    12601 ccgggccagg gcgcactccg gcgccagggt catgccgatg acgtcagcga acgcgcggta
    12661 catcttgctc tccgctctcg tcgagaaccg gggaccttcg atgcagacgt aggtccctcc
    12721 gttgtgaacc ggtatcttgg ccttcttggc ctctttggcg aaaagggaat tgatctccgg
    12781 gcagaacggg tcggccgccc cgatgtgaac ggtcttcggc ccgtcgaaga aggtgtactt
    12841 gcgggacttg gtgaagtcta tgaactggtc taccaggacg atctcgccgg gcttgaactc
    12901 ctcctgcagc gaaccgaccg cgcagggcga gattatccgt tccacgccca actgcttaag
    12961 ggcgtagatg ttggcccggt agttgatcat gtgcggcgga atgacgtgac cgcggccgtg
    13021 ccggggaagg aaggccactg gaaccccttt cagctccccg acctggatct cgtccgaggc
    13081 cggtccgtac ggggtgttcg gacgtaccgt tcccttgagc tcgaacatct tggggtcgta
    13141 taccccggtc ccaccgatta tgcctatctt tgcctgcatg gtgctcccgc cggataaccc
    13201 actggagaat aataaattga ccgtcggttc ccgtggtcca tgggatggac caacatggta
    13261 gaaccttcca ggatggcgaa ccatgctacc aaaccttatt ttatatcctt caaaatctcc
    13321 ggaggggagt cgaagatgga gaagagcgag gtcaatccga tatgggcgtg ccgtgctttc
    13381 ccggccttcc cggtcaccct ggtcgccgtc ggcgacggta acgggaacaa caacatcatc
    13441 acggtggcct tggtgcacat gttctccttc aacccacctg tgctgggcat tgggatctcc
    13501 ccggctaggc acagctacga gatgctcgaa gcatccgatg atttctccat caacatccct
    13561 agcaaggacc tggtcgagga ggtcctgtat tgcgggcagc gctccggtcg tgacgtcaac
    13621 aagttcgagg actgcgggtt cgagcccaaa cagggtaaga agatcaggtc cccggtcatc
    13681 gaggagtgcg cggtcagcct ggagtgcgtt aagcgccaga gggtggacgc cggcgatcac
    13741 gtttggtatc taggcgaggt ggtacacgcg gaaatggcca aggacgccga ccgtgagaaa
    13801 tctctgatgt actggtccgg ggagttccgg ttgctcggcg acgtgatccg gaagcgctga
    13861 aaagctttat taccgtcccg ctcccgttct aatccgggtg ttattctggt caacatggaa
    13921 gataaggtcg atctggacaa tatgggcgcg gtcatggcgc tccctccggc gccggtggtg
    13981 ctggtcgggg taggcgacaa ggagaagaac atcatcacgg tgggcatgtt caacgtgttc
    14041 tcggtgcgcc cgccgatcct gggtatcgcg gtgaccacct cccgctacag ctacaagctg
    14101 ctggaggaga acgacgagtt caccatcaac ataccgggca aggaacttct ggacaaggtc
    14161 ctggcctgcg gggagaagag cggtgccgac accgacaagt tcaagctgac cggcctcacc
    14221 gcggtaaaag gcaagcgaac caaggccccg cgcatcgccg aatgtctgat caacatcgag
    14281 ctgaagaaga cccagtcttt cgaggtcgga gatcacacct ggtatctcgg ggagatcaag
    14341 cacaccgaca tcgtggagaa gtacgaccgg aaagatgccc tgctctactg ggatggggag
    14401 ttctggaccg ccgccgccaa gccgctcaag gtactaaggc ccgactgagg gctgaacggc
    14461 cttgatgaag gagccgaaca tccggacgca ggaggcgctc tccctgagca cggcaagcgc
    14521 ctcggccacc cgctcctcgc gggcgtcccc gtccaggtcc aggtagaaca cgtactccca
    14581 ggtgcggccc tgccacgggc gggactccag cttggttatg ttgacctggt gggaggcaaa
    14641 ggccttcagg cactccagga gcgcccccgg ctgattctta gtggtgaagg ccagggcggt
    14701 cttgttccct tttaccttgg agccttcccg ggagataacg aagaagcggg tgatgttgtt
    14761 cctgacgctc tgcacgtcct ccagcagcac cttcatgccg taggtggacg ctgcgcgtcg
    14821 ggacgccagg gcggcctcat ccctcattcc cctttccttg atcatgcgga ccgagccggc
    14881 ggtgtcgaac gccggcacct tctgccattc tggatgcgca gtaagaaggt cacggcattg
    14941 cgctagcgct tgagggtggc tgtacacccg gcgcacgtcc gcaagctcgg catcagggtg
    15001 tccgatgagg caatgccgga tatgcaccat gacctccccc actactttga ggtcgcttcg
    15061 gaacagaagg tcgttggcgg cggtgacgct gccttcgatg ctgttctcca ccggcagcat
    15121 gcccaggtcg gcgcggccgg aacgaacggc gtcgaacagg tccaggaact ccgggcactc
    15181 caaggccttc gcctcagcgt cccagctgaa caccgcgtcc tcgctgtacg cgcccttctc
    15241 gccttggaac gccacgatca tctcagcacc cgaacagttc ctcgtgaacg gccttggtgg
    15301 ccttatccag gtccgcctcg tcgacggtga agtgatacgc caccagcgaa gctccggccg
    15361 atatcagccc gacgttcact ccctccttgg ccacggcctt gaacacccgg gacgccagcc
    15421 ccttgtgatg acctaggcct tcgccgacta tgcacatcag ggcaaagttg gtgtgggtct
    15481 ccacgcgcgt agccccggat tccgccagca ccttctgggc cttggccacg tccttcttgt
    15541 ctatcagcag ccctatgcaa gtgagggacg tgaccacgct gtagatgttg atctccgcct
    15601 ccctcaatag ggacgccacg tccgccagta ctcctagctt gtagccggtc ccctcgccga
    15661 acaccttcac cagggagagg ttcttcatgc aggagatcga tttgatgctc ttgtccacgt
    15721 tgccggtgcc gccgatggcc gtgccaggcg cctccggtcg gaagacgttc ttcacccgga
    15781 tctctatgtt tcccgaacga gcgggttcca tggtcatggg gtgcacgacc ttggccccga
    15841 aatacgccag ttcggccgcc tcgtcgtagc tcaggcgcgg gatggccctg gcggaaggca
    15901 ctatcttggg atcgacgctc atgaacccgt ccacgtcctt ccatatctcc agggacgaag
    15961 cgcccatggc gttggccacc gccgcggcgc tgtaatcgct gccgttcctt ccgaagacgg
    16021 tcacgcttcc ctccggcgcg cgtccgaaga acccggttat gaccggcgta acgtcgtcct
    16081 gcagcatctt catcagcttc ggacggatgt tggagcgggt ggcctccatg ttgaccgtcg
    16141 ccgttccgta gacgccgtcg gtgattatac cgacctcgtc cgcatcgacc ggccgggcct
    16201 tggagcccat ctcgttgagc agggcggcca gcattatgac cgataggcgt tcgccgaagc
    16261 attggacata gtcacggatg cgggggttca cctcctcgat gtagcaggaa ccgtatagca
    16321 tgcgctccaa cttcaccagc ttggcgatga gctcctccat ggccttcgct cggcctttat
    16381 cggtgctcag cgcgtccttg atcaggtcga tgtgcaactt cgtgatgtcc ttcatgaagg
    16441 cgtccacgtc ctcctcgctc cgggtgcggg agatgaactg caccagcatc tccgttacgc
    16501 cggtgacggc gctgaggacc acggccttct tctccttctc ggcgatgatg atctcggcca
    16561 cctggcgcat gttctttccg gtcttgagcg aagagccgcc gaacttcagc accttcagtt
    16621 ccgccacctc cgcttgatga tggccttggg cgtctctatc agcgccagtt ccgcctgctc
    16681 ccgggtgagg ccggccgcca aggcgatctg cgtggcggtc gccaggtcta taaggtcgcc
    16741 tggagagtgg gcgtcggtgt tcacgaccat gagcgctccg gactgctggg ccatgcgcgc
    16801 cacgtgaccg ttggtcttgc agtgcgagcc gcgggacgtt agctccagca ccacgccgtt
    16861 gtcgcgggcc gcctgggcct cctccagggt tatgaagccc gggtgagcca gtatgtccac
    16921 gtcagggttc atgaccgccg cgtagttggt ccccttctcc accggctcgc ttatcgtctc
    16981 gccgtgaatg acaatgagct cggcccccag ctttcgggcc ttggacacca cttcgtctat
    17041 gcgccgggcc ggaacgtggg tgatctccac tcccgccagc accttcatgc cccattcctc
    17101 ggccagctcg gcgtcgcggc gtccttcggt gatcacccgc tcgagattgc tcagagaggc
    17161 gtgatcggtg aacgccatat gcttggtccc tttgacgaat gcccggcggg ccagttcgat
    17221 cggaagaagc tcgccatcgc ttatcagggt gtgagtgtgc agttcggccc tcattttctc
    17281 ctctccgcca gtttccggta gacgtccgtc cactcgacct ccatcccctc caccgccacc
    17341 atcaggtggt agatgaggtc ggccacttcc cacgattgct cggcggcctg gtggtccttg
    17401 gccgccagga gcacctctcc cgcctcctcg accactttct tcaagcgctt gttctcgtcg
    17461 gcgaagagct tgcaggtgta gctgtcgtcc ttggggttcg ctttgcggtc tctgatgacc
    17521 tgtagcaatt gcggcagcac ggccatggtg ccttcgatgt cgccgtagac cacctcgtcg
    17581 aagcaggaca ttcgttccag gtggcaggcc acgccggtct gcttgacgcg cacgagaagc
    17641 gtgtcgttgt cgcagtccag ctgcatggag acgatctcct gcacatgtcc ggaggtctcc
    17701 cctttcttcc actgttcctt ccgggagcgg gagtagaaat gagtgaaacc ggtccgcagc
    17761 atgtcccggt acgcctgctc gttggcgtag gccatcatca gtacctcgtt ggtctcctgg
    17821 tcctgcacga tgaccgggat gagaccatcc tcaccgaact tagggctgct catctcacct
    17881 caactccgtt ctccttgaga tacgccttta catcccgcac ggtccactgg ccgtaatgga
    17941 atatagatgc cgccagggcg gcctcggcct tggtctcctt cagcacgtcc agtatgtgct
    18001 tgggggaacc gcatcccccg gaggctatga ccggtatgtt gactgcttcc gcgaccagct
    18061 tggtcatcgc gatatcgtaa ccgtccttgg tcccgtcggc gtccatgctg gtgagcagta
    18121 tctcgccggc gcccaggtcc tccaccttcc gcgcccactg caccatgtcc atcttggcgt
    18181 ccttacgccc gccgtgcgtg taaacggtcc agtcgccacc ctggcgcttg gcgtctatag
    18241 cgacgacgac gcattgcgag ccgaagtcct tggcgcattc ggagatgatg tcgggacgct
    18301 gcaccgctac ggtgttcacc gagaccttgt ccgccccggc gttcagcgcg gcgcgcatat
    18361 cctccttctc acggatgccg ccgcccacgg tcagcggaac gaagaggcgc ttggccgttt
    18421 cctccacgat gcccagtagc gtcttgcgcc cttcggccga agcggagatg tccaggaaca
    18481 ctatctcgtc cgctccctgc ctctcgtacg tttccgccat ctccggcggg tatcccacgt
    18541 ccttcaggtc caggaacttg atgcccttga ccaccgcgcc gttcttgacg tccaggcagg
    18601 ggattattct cttggtcagg ctcatccctt gctcaccttg ggccggtcct tggtgctcag
    18661 ctcgctgagg cgcggaagca ccgccgatct cagcgccttg cccagggcct tgaaggacgc
    18721 ctccacgatg tgatgctggt cgtagccgcg gatgaccatg atgtgcaagg tgatcccgga
    18781 ggacatggcg aagctgcgga agaagtgcgc gtacagatcg tccggacaat ccacgtccgc
    18841 gtacggccgc tcgatgatgt ccaccgccac ctggaccagg gcatcgtcca tggggatgag
    18901 cgaaaaggcc gtccgctcga tgggcgtctc gcccaggcac tgcttgaacg ttttcccaag
    18961 aactatggcg acgtcctcca ccaggtggtg cacgtcgtcc ccagatgcct ccagcgtgag
    19021 atcgaaattg gcgtagcgtc ccatggtctc caccatgtgg cgcaggaact gttcctcgca
    19081 ctccaccttc gtcacgccct cgccgtccag gtccagcttc agccggacct cggtctccct
    19141 ggtcttgcgc actacctcgg tcttgcggtc catggcctca tctccagatg gctttatgat
    19201 tcagttttcc agtataaagt gataatccca ccaccgcctc ctccacgccc atnnnnnnnn
    19261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nntccagggc caggaccatc cgcttgggat
    19381 atttcaggga catcgtcctc agccaggccg ggtccttgag ccccttcgtt ccggcgatga
    19441 cccggtcggc gccgcagtcc aggaagtatt cggcgacctc cgtggaacgt atgccgcctc
    19501 ccacctggac cgggacgtcg gacctctcta tgatgctccg gatgacctgg gcgttgtgtc
    19561 cctttcccag ggccgagtca aggtctatga tgtgcaatcg tttcgctcct ttcgactccc
    19621 aatccctagc caccgtcagc gggtcgggca gggtgacctg ctccgtgccc ggtacgccgc
    19681 ccaccaactg aacgacccgg tggtccagta tgtccactgc cggtatgatc ctcatgtcct
    19741 ttcctccgcg aagcgcacga agttgttcag gaaggccatc ccggcgaagg agctcttctc
    19801 cgggtggaac tgcgtgccgt aggtgttcga cttgtggaac agcgtaggga ttcgtccaaa
    19861 gtaatcggtg tgccccacgt ccgatcggtc ctccgggcgg ccgtggaagg aatgggcgaa
    19921 gtagaagtgg gtgtcgtcca cgccgttcat gatgtcgtcg tccgtttcga cggtgttcca
    19981 gcccatgtgc ggtatccgcg gcgcctctag cctgaccacg ctcccgtgca ggaaccccag
    20041 gccgggtccg tcgccctcgg cgctgttctg gaaaaggatc tgcatgccta tgcagatgcc
    20101 caggcaggga accccttcgt tgagcctctg gactatctca tctttgtagg gcagcagacg
    20161 ctccatcgtc ctgtcgaagg cgccgacgcc agggagaacg atgcactccg attccctcag
    20221 caaggacatg tcctcgacga cggtgacgga agcgccgcag ttctccaacg cctttcgtat
    20281 ggagtgcaga ttgcctacgc cgtagtcggc cagggacacc ttcaacggca ttccctcagc
    20341 acctcccgca tcctatccag caggacggtg ttcatctccc gggtgcctat agtggtccgt
    20401 atgcagttct ccagtcggcg gaccttgccg aagtccctga ccaggacccc cttctccgac
    20461 agcttcttgg taaggacatc ggacggcatc tccggacgga acaggatgta attggcctcc
    20521 gaggggaaca cctggaagcc cagatcgctc aatcccttgg aaaggaacgg ccgctcctgg
    20581 ttcaccaggc gaacgcttct ctccaggaac tcccggtccc gcaaggcggc gatcgccact
    20641 cgttccccga tcatgttcag cgagtacggt atcttgacct tctgcaaggc ctcggccatc
    20701 tcaatccccg cggccaggta gccgatcctc attcccgcca gaccgtacgc cttggagaag
    20761 gtgcgggtga ccatgagatt atcgtaccgg tccaccaatg gaaggaacgt atcgttggtg
    20821 tattcgccgt acgcctcgtc cacgatcacc gggcggtcgg ctccctcgat cacggccttg
    20881 aggtcgtcca cgcggaaggt gttggcagtt ggattgttag gggtgcacag caggaccact
    20941 tttcccgggg tggagttgat cttatccaca tccagctgga aatcgtcatt cagatcgacg
    21001 gtgaccgtcc ggccgccgtt gatcttgacg aagaaggagt gcagcacgta cgcggggtgg
    21061 gcggttatca ccgtctcacc gggctccatg aaggtcttca ttatgatgtc caggacctca
    21121 tcggaaccgt tgccgaccac gaaattgtcg gccttcatgc cgtacagctt ggccagttcc
    21181 tcacgaagtt tgtcgccgta ggtgttcgga tactgtccca cgttcagctt cgtgcattcc
    21241 accagctccc gctgcccggc ggggttggcg cccaaggcat tggtgctggt gtccatgcgc
    21301 agcttgtcgc cgacgttcgg attgtaatag agctgcaggt cccgacaggt ggatcgtatc
    21361 cagtccttgt tcatgtgggc cacctcaggg gaccatgcgg tctatcggcg tgagcaggat
    21421 gcccgtggcg cccatgcgct tgagcttgtt gatggcatcg aacgcgtccg tcttctcgat
    21481 caccacgtgc acggcgacca cgtcgtcccg gccgatgatg ttcatgatgg tcggtccggc
    21541 gatgcccggg aaggccttct tgacctcctc caacgaggac ttcggaacgt cggccatgag
    21601 gtacttcttg ttctccgcct cggtcacgct cagcatggcg gagattatct cctgcacctg
    21661 ctgctcgcat ccctcgtacg ccttgcggtt ggcgatgacc acggcctgcg attcggtgat
    21721 gaccgccagc tcccgcaggt ggttcatctt caatgtcgaa ccgctggaga ccaggtccac
    21781 gatgatgtcc gccacgccca atatcggcgc tatctcggcc gctccggaga tgatggtgat
    21841 atcgaccttc ttgccaagct tttcgaagta ttgcttggtg aggttcggga aggaggtggc
    21901 gaccaccagg ccgtccggca ggtcctccgg cctcttcacg tccatggtgt ccgggacggc
    21961 caccgacaga cggcagcgcc cgaagttgag gtgatatgga acgatgacat ccagtcccga
    22021 ttcgagaacc aggtcgtagc cggttatgcc tacgtccacc gcacccttgt gcacgaactt
    22081 gacgatgtcg gatgcccgga ggaacatgac cgccaggtct tggcgtttga cgttggcgta
    22141 gagcctgcgc tcgtcgccgt tctcgatctc cagtccggct tgcttgagga tctctatgga
    22201 cctctcgctc agccttcctt tgttgggtat ggccagcctg agtgtcatgt gataaccctt
    22261 ggcacttgcc atcaatggac aattgctact tataattact gacattctgg tcgtgcgccc
    22321 gcgctcggag ggggcattct gccaattttg ctggtatgta acggttcgtt ccctccggac
    22381 ggcaattgcg aattctcaaa taaaccggcg gaaatgaggc ggagcatggc ggcggaggaa
    22441 tggcaggaca tctgggagat ggccaattca cattctccct atcgaacgtt cccgatggac
    22501 cgccagcgac tggtgcagca ttggaacgag gtgtccaagg attacgacag cgagtcgatg
    22561 tcgctgatcg acgaacggat atggggtttg ctggaggaca tgtccgtggt cccgggcggg
    22621 aacgccctgg acatcggctg tgggaccggt tcgttgacgt ccatgctggc ctcggaatgc
    22681 tcccacgtgc tcggcctgga catctcgccg ggcatgctat ccgtggccaa ggagagatgt
    22741 tcgagcttga acaacgtgga gctgctgtgc cagggctggg aggagttctt gccggaacgt
    22801 cgcttcgacc tggtgttctc ctccttctgt ccggcggtgg acgatgttcg ttcggtgatg
    22861 aggatggacg ccatgtccga cgggacctgc tgcatcgtgt ccctgggcgg ctcgtccgga
    22921 gaccgcctgg cgttcgacat ctgggaggag ctcggacatc ctgggatgtc catggagggc
    22981 ttcgatccca tcttccccta ccgcatcctg aaggagatgg accgccgacc gtcgctgaga
    23041 cgtttcgacg tgcacgagga gacggagatg gcggcggagg acatggtccg ccatctggtt
    23101 cgttacttct cattgttcca cgaggtggac gaaagggtga agaaggtgat cgctgacagc
    23161 gttcaaagaa gatcggacgg tcggcgtttc acgctgcggg aggaccgcac ggtgagcgtt
    23221 ctgaagtgga cggcgattta gaaacggatg cgggtgatcc tgtccggggg aacgtcgcag
    23281 cgcaccaggc ggggaacgtc gcctcctatt cccagcttcc cgttgatcat gaccagggca
    23341 cccttgaccc cctttatcga caggacctcg cgtatggagc ggtccatgag cgtcaggtcg
    23401 tcctcggtta tcaggttccc cagcttggtg gcgcaggcgt cggcgagggc cacgtcctcg
    23461 gagatcaccg tggccaggtc cgccctcccg aacgagatgg acgggccgac ggttccggag
    23521 gaggtgcaga tgccgagcat ccccttggtg gccggaacct ccaaggccag atagttaggc
    23581 gtgcgctccc cggcgtacag tccgacggtg atggtgcggt tggtgcgcat ggctatgtcc
    23641 ccaccgttat cgaccaggca gtgcttgcac ccctggtcga ccatggtgcg cacggccttc
    23701 tgggagatcg ctccggccac ggccgccatg gggcccacgt ccgccttctg cgcggcgttg
    23761 cacatgttct tgaccacatc gcccatgtcc gatctcacgg cgtacggctc aaaggtcgtc
    23821 ttgaagtagg ggtccttggc gatgtaagcc tccacctgct cccgggcctt aagaagggca
    23881 tcctccgcca ggggaaggta ttcctcgtcg gcctcgatgg tggcggcggt ctccttgaac
    23941 tggaaaagcc tcctcatatc ctgaacttca ttgctcctgg aggacaggcg tctatgcaca
    24001 tgccgcaagc gatgcacttc tccgagtcgt aacggacctt ccaggacggc cggtccatgg
    24061 tcagcgcctc caccgggcag atggagatgc acatgccgca atgggtgcag cggtcctcgt
    24121 tcttctccac gtaggtgatc agctcctgaa catcgacctt cgcttctcca agataccgag
    24181 cggcctcctt gatgttgaag gcctttccct cgacctccat tagcaaacgg ccgcccatct
    24241 ctcgcacctc ggcgcggagg atgttgatct tgaggtcgta atccttcacc aggcggtaga
    24301 cgatcggctc gttcacgatg tccgggctga atcccaggag gaacttcttc ttggccatca
    24361 gaccgcctcc tccttggagc ggacctctaa ggttcccatg cttctgtccg caggtaagga
    24421 agcgaccggc tcggtcagca ggaactcccc gctctctata cgttcggaga gcgcttccgc
    24481 gatctgcctg gccttgagat agctggagag ggaggaggtg cgcacctcct ttccgaagag
    24541 ctcgacccgg ccggagcgca gttcggcata tgagaagtgc ttgagcggct tgcggttgcg
    24601 tgactggacc gagtaatcga tcagcggagc gaacagctgc tcgtcgctta tcgccgtcgc
    24661 tctaagaacg tcctcatcca gtatcgggat cggaataccg attcccaagg ccagggatac
    24721 accgtagccg ggcaggctca acgcccgaac gaactccggg gacatgcctc tcatgtcccc
    24781 tatggtagcg agattacgcg caccgcccat gggcgccccg aactgggttt ccacgttggt
    24841 cttgaactgc gtcccctccc aggccacgta accgacgccg ccgcccagga atatccgggt
    24901 accaattccg atggtgcgca aggaaggatc gttcagcaac ggcgagagct gaccggcgct
    24961 ggagtaggtg atgttgccgt agttcgatag cagcttaccc atgtaggtgt acaaggtgcg
    25021 atcggaggag ttggttcccg ccgcgtagtt ctggtagacg ttgcgcggat tgaagagata
    25081 ggcctgattg atggtgttca aggagacgaa cgtgtcaatg tccttgcgcg gatagcagtc
    25141 cgtcccgtcg gaagtggcct tcagacgcac cgcctttccg gagatcagct cctcgatgac
    25201 gtgcgccccg ccgtacccgc tgtgatcgtc cagcttcagc tccgtagcgc cgatgtaagc
    25261 atccacggcg gcgatgccgc cgtaggccgg aacatcgttc agggtgacct tctgcatgcg
    25321 gatcggcggt tcggagtgac caaagttgag gaaggccccg gaggagcaca tggccccgaa
    25381 ggtcccggtc gtaacgacgt ccacctcctt ggcggcgcgc tccacgccct cgctctggac
    25441 gaatgatatg acctcctcgg cggtcatgac caccacgtcc ccgtccttga tccgctgatt
    25501 gatctccgcg accgtccgct tcattccgca cccctttata ggaacttctt ggccacagcc
    25561 agttccgcgt ttagaacgga gccgccggcc ccacccctca gggtgttatg ggaaagcaac
    25621 cagaacttga tatatccttt gctctcgcgg acgcgtccaa cggacaccgc cattcccctg
    25681 gctcgttccg gttccccggc tagcgcgtcg gctgccggct gcgggcggtt ctcctcccgg
    25741 cgcacaatga tcggttgaac gggagcggtg gggagcttca gcttctgtgg ctcggacacg
    25801 aaagcatcca gagccttgat gatcgcttcg gcgtcggcat ccttctcgag cttcagcacg
    25861 gccgactcca ggtggccgtc gatgaccggc acccgggcac agctggccac catgtcgaac
    25921 tccgcgaact tgagcttgcc gttcttgtag gcgccaagca tcttgtgaat ctcctcctcc
    25981 atcttctcct cctcattctt gatgaaggga accacgttcc ccaagatgtc cagcgacggg
    26041 acgccagggt aaccggcgcc ggagacggcc tggtaggtgg agacgtagca ggccttcagc
    26101 ccgaacttct tgtagatggc ctgcaacgga actgctaggc cggtcgtcga gcagttggcg
    26161 ttggtgacta tgaaaccccc gtttccgaac gtggattgct tccgaaccag ctccagatgg
    26221 tccgggttga cctccgggat gagcagcggg acgtcagctc ccatgcggtg cgaggcggca
    26281 ttggaaaaga ccgccacccc cagttcggcc aacgaggact cggtgtcctt ggccacctcc
    26341 gtcggcaggc cggagaacgc cagacggttg cgcttagcta ccgccttggg gtccaggctc
    26401 tcgatcttgg tggcgagcgt ctcctcctgg aagcgtatgc ccttcagctt catcacctcg
    26461 cccagcgatt tgccttccga gcgctcggag gcgtagaggc cgcctatctc gaaatagggg
    26521 tggtcctcca gcagttgcac gaacctctga ccgatcattc ccgtggcgcc tagtaccgcc
    26581 acctgcactt tcttcattgc ttcacctcga aatacttgcg accttcatgc atcagcctga
    26641 tcatgtgcga ccggtcctcg tcggacccgg ccagctggac ctcgcgcagg gcgtcgatca
    26701 gcttgtccag catctcactg ttgtgcgggt tcagatgctg gatctcgtag taaaggtttg
    26761 ggctctctcg cgcgacactt ccgctggtgt tcatctgccg ctcgaaggtg gtggaggaga
    26821 ccttcctgag ctcttcgtaa gtgaaaccgc tttccttgag cgctccgaag aacgccaggt
    26881 tcaaggcgtg gctcatgccc aggaccaccg agatgatctt gtcgtggtcc tccaccggca
    26941 tctcgatgac gttggcgccg gtgccgttca gcaggggcat gaacttgttc accgcgatat
    27001 cggaaccgca attgcacacg atgaggttgc gagcgaatat gaacgaggcg cttggcccga
    27061 acatggggtg gatggagcat accagcagcc cctggtccgc gccctccttc agcacgtcca
    27121 tgatgggcga tttgacggag gcgatgtcga agatgagccc cttaggtctg agcgcgaata
    27181 tcttgcgcag catgtccgcg gtggccgaaa tgtgcgatga gacggcgatg acgtccgcct
    27241 ccttgacgcc ctcttccagc ttgacgttct ggaactctcc gccgggcaga tcgtcaaaga
    27301 ccttaacccc gtgtcctcgg gaggcgaaga agcggcaaag ccactgcccc atcgccccgc
    27361 cgcctccgac caccagcacc tggcgtggct tcatcgggcg cggaagccgg gcctgggctt
    27421 ccaccgattc ccgcaccagc agtgcggaga gctctaccgc cgccgcgtcg ctgatgccca
    27481 cctccttggc ccttgccaag tatctgttcc gtacctggtc ctccacgcgc atatcgcgca
    27541 ccggcatggc cttgtccacc ttgtggtggc ccatgtccac ggcgatgttc atgcgcttct
    27601 ttatcaggtc caggatctcg ttgtcgatct cctcgatctt ccatcggatg ccttccacgg
    27661 aatcagtcaa ccgtaccacc tctcatgctc aggtccgcca gcaccagcgc ggcagccgcc
    27721 tcgacgaccg gaacggcccg aggcgcgatg cacgggtcat gtcgtccctc tatcttaagg
    27781 tcggtctgcc taccgctctt gacatccagc gagcgctgcc ctctggcgat ggacgccgtg
    27841 ggctttatgg ccacccggaa gacgattggc atgccattgg ttattcctcc caggatcccg
    27901 ccggcgtcgt tcttggaggt gcgcactttt ccgtcaacca ggatgaaagg gtcgttgtgc
    27961 tgcgatccgc gcatcccggc ggcggcgaac cccgccccga actcaacgcc cttgacgccc
    28021 ggaacggcga acatcatctt ggacaattcc ccttccacgg tatcgaagaa aggttctccc
    28081 agcccgatcg ggatgccgtc cacgatgcac tccaccacgc caccgacgct gtcgccgtcg
    28141 tccttggcgg ccaatatctc ggagcgcatg gcctcggcca attcgtccgt ggccgctcgg
    28201 acctcgttcg aacgtgaaag caccccggag gtgacgtccc tctcctcttc gtcacggacc
    28261 cgccctatct gccgcgcgaa ggcggcgacg cgtatcccgc gctcctccag aagcatcttg
    28321 gctatggctc ccgcggcaac tatggccacg gtcatccggc cggagaactg gccgcctcct
    28381 ctcaggtcca cgcactcgga atatttggag cgggcggtga ggtccgcgtg tcccggacgg
    28441 ggaacgctct tgaacctgtc atacttcttg gagtcggtgt cccggttcat gaccatcagg
    28501 gtgatcggtc ctccggtgct tttcccctcg acgatgccgg acacgatctc gaccaggtcc
    28561 tcttcctgtc gcggggtgcc gatctccgtc ctgggcttgc gaaggtccac ctcgctctgg
    28621 accctcccga ggtcgatcat cattccggga gggaccccgt ccagcacggc gccgacgcat
    28681 ggtccgtggc tcgctccaaa taatgttagc cgtaactcgc tgccgatggt gttcaaggta
    28741 tcatctccat ctttgcgccc aaggagagca tgtcgctcac gaaatccggg tatgagatgc
    28801 ggtggcagtc gccatcgcca attatcgtct caccgctggc ccttaatgcc gccaccgccg
    28861 cggccatcag tatgcggtgg tcgttgaatg agttgacgtg cgttccatga agcggtcttc
    28921 cgccacggat cacgcagccg tcctccgtct ccctgatgtc cgcacccata tccttcagga
    28981 acagggtggt ggccgagatc cggtcgctct ccttcaggcg gacatgggcg gcgtcgtaga
    29041 tacggctctc ccccttggcg aaggcgcaca tcaccgcggc catggggaac aggtccggag
    29101 cgtcgcccag gcctatgtcc gtggcgacga gttccgcaga ggaacaggtt atcgaatcgc
    29161 cggcccattc caccttcgct cccaaagatt ccaggatttt caggaaggcc cggtcgccct
    29221 gggcgtcctg ggggtccagg ttcctgacgg tgacctttcc ggtcagggcg ccggcggcca
    29281 atgggaacgc cgccgaggag aaatccccgg gtacggtata atcctgagga aggtagcgct
    29341 gaccgcctcg caccaggaac ccctgctcgg tggaacggca gttagcaccg aagcgggcca
    29401 tcatctccat ggtgatgtcc acgtagggct tggatttcaa aggggtggtg agaacgatct
    29461 cggtgtccac ctccttgacc gccgaggata tcagcaacga ggatatgaac tgtgaactga
    29521 cgtcaccgcg tatctccgtc ctcttcccga ggttcggacc tctgacgatg aggggagcca
    29581 tgccgttccc gcgggtgctc tcgcagcgca cccccatcat tcccagggcg tcgatcaggg
    29641 gctgcatcgg tcgccgcctg atgctgtcat caccagtgag cgtggtttcg caagatagta
    29701 acgaagccac cccggccatc agccgtatcg tggtgccgga gttctttaca tcgatgattt
    29761 tctccggaca tctcagatgt ccgccggtga tgtgcagagc gtcgttcctc gccacctttc
    29821 cgccgaacgc cgtcaccgcg tccaacgtgg ccaaggtgtc ctctcccagc aacggccggc
    29881 gcagaacgct ctcgccatcc gccagcaacg ccagggtcat cgcccgatgg gtgtagctct
    29941 tggacgggga cgacagaacg atgccttcgg cgttggacgg aacgaccctc aaacgcaccc
    30001 tcacaccccc tgatagacct tggcgatgat agcgtccttt cccagggcct cggcgaccgt
    30061 tctctccgtt ccagcatcga cgaaggatgc cacggccggt ccggtcccgg agatgcccga
    30121 ggcgatggca ccggctccaa gcgccttgat cgaaagttcc tggtccagtc ccagcgccgc
    30181 tccgtaaatg agcgagttca gggtcatggc cttgacgtat tcgccgttcc aggccaggcg
    30241 gaacgcctcc tccgccaacg ggtgatagag ggcgatgcgc tccttcggca ggttcgtttt
    30301 tcgtatcatt cgttccggaa cggctatcac cacctgatcg ctgaggtcga aacgctcgcg
    30361 gcggaggagc gtccgggcat gattgtcagt gaatacgata ccccctagga gggaggcggc
    30421 cgcgtcgtcc agggccccgg tcaccgaaac gccggcgccg atggacacct cggcgttcat
    30481 cttcagtata tcaatggccg gcatctccat tttgagagcg tccaaggtgg ccagtatcac
    30541 ggcgttcgcc gcggcgctgc tgctcttcaa tcccctggac accgggatct gggagccggt
    30601 gcgtacgatg gccctctttc tcagggagaa gcgctccagc accgcttgaa cgcacatctg
    30661 gacaagcttg gacggctcgt ccggaagacc ttccagatgg acctccaccc cttcaccggg
    30721 tatcagcgcg acctccgccc aggtgcgcag gtccacgccg accgcacagc ccttcccggc
    30781 ggcgatagcg ttgacgatgg tcacggcgcc catggcctct ccccggcctt tcaaggcagc
    30841 gcctcccgga aggccttctc catgacctcg tgctccacgg cctttccggt ccacatctcg
    30901 aaggaggcca aggcctggta gatcagcatg tccttgccat tgaccgctat ggcgttcttt
    30961 cgcgacgcct ccgcgaggag cggtgtaacc ggcggattgt aaacggtgtc catcacgaac
    31021 tgcccctcgc ggagcacgtg cggggatatg gacatctcct gcgggaagcc cttcataccc
    31081 aggggggtgc agttcacgat cacgtcgtac ttcttctcct cggccaccct attggtcacg
    31141 gcgttcgccc cgaacagctt ggccagcgat tccgcctttc ccatggtgcg gttggtgagg
    31201 tccacgctcg ctcctttaga gaccaggaac gagagcacgg accgggaggc gcccccggcg
    31261 cccaggacca gggcggtctt tcccttaacg tccacgttat ggtgctcgaa cgttctttcc
    31321 acgccgatga cgtcggtgtt ccttccgacc aaagaacctt cctcgttgac cacggtgttc
    31381 accgcgccga tgcgctcggc caccgggtcg acgcggtcca gcaacggaac tatcgattcc
    31441 ttgtggggga tggtgacgtt gaagcccttt atgcccaagg tggccaccac gtccaggaag
    31501 tcctccagct cgtcgaccat ggtcacccat ttcaggtaca tgccgcggac ggcggccgaa
    31561 cgaaaggcgg cgttatgcat cactggagac aaggtatgat cgagcggata gccgactatg
    31621 ccggtgacga tcggctcctt gcccagccac ttggccgttt ccaggtcgag ctg
//
LOCUS       DAOPZI010000016        30777 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1426_length_30777_cov_10.888549, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000016 DAOPZI010000000
VERSION     DAOPZI010000016.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 30777)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30777)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30777
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1426_length_30777_cov_10.888549"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..410
                     /locus_tag="PKM11_04490"
     CDS             <1..410
                     /locus_tag="PKM11_04490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HNX47799.1"
                     /translation="DPRGKVPENALVLDARARTLVVTLEDCARQYPGAETVRLGKGAI
                     DLQALLDELGRRGVSTLLVEGGGETIHSFFKAGLVDVYSVFVGDFIIGGRESPTPVDG
                     EGFRMGEHVQLRLVSVERLGFGVHLTYEVWRDD"
     gene            403..849
                     /locus_tag="PKM11_04495"
     CDS             403..849
                     /locus_tag="PKM11_04495"
                     /inference="COORDINATES: protein motif:HMM:NF014037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mut7-C RNAse domain-containing protein"
                     /protein_id="HNX47800.1"
                     /translation="MTEPSFLLDGMLGSLARWLRIMGYDSVYMRNEDDLTLLSIRGDR
                     YLLTRDRQLAQRAGSQGLFIESDKLDVQLSAVVKRFDLRFDIQRTRCTACNGRLEKVA
                     KELIKDRVAAGTYDEIQEFWMCQGCGKVFWHGAHWKNIGHRLDGLS"
     gene            complement(842..1762)
                     /locus_tag="PKM11_04500"
     CDS             complement(842..1762)
                     /locus_tag="PKM11_04500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47801.1"
                     /translation="MTTLNAVLKEILETRGFLVDQVGPFVRGRRDNIELHFFPYVRHS
                     PAAMEELVKTAPVTKGKVVLAALVPLAESTLAALPPGLVVWDREAVEHEIGRTRIEKL
                     VGEEDHGLIDDLYADDVPMLDDDHSGVGEERILPMRISLQEVVELTSKTVGGYSQRLE
                     LVPHYVFAYQVPLFVGEGKVGGREGNMAVNALTKGVQPWDQVPETVTNLDQGYKRLEP
                     VLEEEDATALVRTTVEREHTYDRDMIRENGQVTMTERVTVHPRLDLGSVRPLGIYYVP
                     IWCVEGTKGVMIIDASNGKVLSEDYFRDIS"
     gene            complement(1799..2782)
                     /locus_tag="PKM11_04505"
     CDS             complement(1799..2782)
                     /locus_tag="PKM11_04505"
                     /inference="COORDINATES: protein motif:HMM:NF016356.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="HNX47802.1"
                     /translation="MPDPKPRVVVSRCIEFEACRYNGAMIKSEFLLRLMPYVEFLPVC
                     MEADMGLGVPRDPVRIVRLDGEDHLMQPSTGRDVTETALRFTREHLANLRDVDGFLLK
                     NRSPSCGIKDVRVYPPGEGKAVLTGKSAGIFAREVMSAFPHLALEDEARLLNGRIADH
                     FLTRIFTSARFRGCREKGTSKALMDFHARHKLLLMGYSQAAMRRLGRITASQAPIEER
                     LQDYSVELHNALRRPPSCRSWNNVLMHAMGYFSDELDVKEKQHFLRSLEWYAEGKVPL
                     TAPLLMVRSWALRKGEEYLLQQVLFEPYPEEFMGLLGTEACTGRDLWEDAR"
     gene            2835..3206
                     /locus_tag="PKM11_04510"
     CDS             2835..3206
                     /locus_tag="PKM11_04510"
                     /inference="COORDINATES: protein motif:HMM:NF014100.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF131 domain-containing protein"
                     /protein_id="HNX47803.1"
                     /translation="MRREWLWVAIVALLLSSVALGWMAWEKGEVELYLFLIFPVLKAD
                     GVYGAAALLLAFATMVLVLFALFAWRSPDDTKPERGTSVGGVIMIGPIPIVLGSDRRT
                     TIIALILALVVLMIIILLLVQ"
     gene            complement(3189..3407)
                     /locus_tag="PKM11_04515"
     CDS             complement(3189..3407)
                     /locus_tag="PKM11_04515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47804.1"
                     /translation="MEPLNEGLKKVLADALDKRRRDDTVENAVSREARRAGLRYQDYL
                     DIMEAVRVLSRKDKLDPWMAAKALLDQQ"
     gene            complement(3395..3970)
                     /locus_tag="PKM11_04520"
     CDS             complement(3395..3970)
                     /locus_tag="PKM11_04520"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase subunit A"
                     /protein_id="HNX47805.1"
                     /translation="MRVYVVDNGGQWTHREWRVLKYLKVETKIIPNTTPFDQIGQVDA
                     LVLSGGAPDVASEAGRMGNNGEYLDKADFPVLGICAGMQFMATHYGGSTGPAVRAEFG
                     RARLYVDQEDHLFQGVPREFDVWESHNDEVKVVPDGFEVLAHSDTCLVEAMRSLRRPL
                     YAVQFHPEVENTDFGMDIFRNFLKAVEEWNR"
     gene            4069..4782
                     /locus_tag="PKM11_04525"
     CDS             4069..4782
                     /locus_tag="PKM11_04525"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HNX47806.1"
                     /translation="MKAVIFDLGHTLIDYYHDWAGPEERIVSRLYRLAAETGGGLPEP
                     EFRRSVLATLQGNRERKLQDMLEIPLETVLDRLFSSAGCQVDEGLVQEGMEIFYQALK
                     EDRSLVPGTLEMLQRVRDRGCSIGLISDVAWGLPSEYPLRDMKHFGLDGYFDDLLFSS
                     DVGLRKPNPRLFKMAMFNLGADRDGSMYVGNSLQADIKGAKSVGMKAVLKKSGYFQPD
                     DSIVPDHTVDDWKELDELV"
     gene            complement(4783..5730)
                     /gene="guaA"
                     /locus_tag="PKM11_04530"
     CDS             complement(4783..5730)
                     /gene="guaA"
                     /locus_tag="PKM11_04530"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HNX47807.1"
                     /translation="MFDPQEFVKEKIEELRTKITGKAIIACSGGVDSTVAAVLVDRAI
                     GERLLTVYVDTGLMRQGETEDVRRMFDNLNVHYRLVDAKDEFFAALKGQIDPEAKRKA
                     IGEKFIRVFEREALAFGADHLVQGTIAPDWIESGDGVRDTIKSHHNVGGLPKDMTLKL
                     VEPLWDLYKDEVRAVARFLGVEVSERQPFPGPALAIRVIGEVTPESVSVVREACAIVE
                     EELEAASDKGSMVRPWQYFAVLLPVQSVGVQGDRRAYGRTVAIRSVESVDAMTASFSK
                     IPYDVLERISLRITNEMKANVNRVVYDVTHKPPATIEWE"
     gene            complement(5730..6197)
                     /gene="purE"
                     /locus_tag="PKM11_04535"
     CDS             complement(5730..6197)
                     /gene="purE"
                     /locus_tag="PKM11_04535"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HNX47808.1"
                     /translation="MASVLIILGSKSDVEVGRKALDVLKRFGVEAEMIVASAHRTPDR
                     VKLMVDRSKADVFIAVAGLAAALPGAVASFTCKPVIGVPVSGKLGLDSILSIVQMPPG
                     IPVACVGLDRGDNAALLAVSILSIGDPKLAQALSSYRQEMAEKVESDSNEVQA"
     gene            complement(6271..6567)
                     /locus_tag="PKM11_04540"
     CDS             complement(6271..6567)
                     /locus_tag="PKM11_04540"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47809.1"
                     /translation="MDLMQFLTVLLLTFSLVMILAGAFTAYFGSGKSRMIGVVLLVVG
                     LLVGVVWGYLGYADMAGVEVDISEVVWVAFVNILAALIGALVAVGAFLLAIMKS"
     gene            complement(6769..7689)
                     /locus_tag="PKM11_04545"
     CDS             complement(6769..7689)
                     /locus_tag="PKM11_04545"
                     /inference="COORDINATES: protein motif:HMM:NF012515.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HNX47810.1"
                     /translation="MRPFLCVYGHTNIDHLLALKDLPERNTSSNVISKKSYFGGTGAN
                     LATMASALGVPTALVSYVGKDLPPEFRRLMESNGVILDELVEVDGQETPTVWIATDEK
                     EDQVAYVFQGAMANMGSYPIQVKGAKDALAIHLMTGSPDYYLKLLARPNLLRKRRGLD
                     PAQEIHHVWDAERFQKALDFTDMLFCNRNELATALRYTGKDSPEDVLDSYRGMQVIVN
                     TLGGQGARIYGRNEVLDVPAAKVEVVDPTGAGDAFRAGFYAGLYRGKSWLECGVLGSA
                     AASFVVSSPGSLTSIPDWGMVEERARSLRR"
     gene            complement(7686..8930)
                     /locus_tag="PKM11_04550"
     CDS             complement(7686..8930)
                     /locus_tag="PKM11_04550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004013 - adenosylhomocysteinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylhomocysteinase"
                     /protein_id="HNX47811.1"
                     /translation="MDKELLLKGSRRLGWAEAHMSVIREVGERMRQEGSLKGTKVGMA
                     LHVEAKTGMLAVTLARAGARVRLASCNPLSTDDSVALALKEERGIEVFARKGESNKEY
                     YENLNAVLDMRPEFVIDDGADLITMLHTSRREQLDEVKGGNEETTTGVIRLQAMAADG
                     KLKFPVMAVNDAKMKYLFDNRYGTGQSTFDGFMNATNLLIAGKTLVVAGYGWCGRGVA
                     MRAKGMGAIVIVTEVDPIRAIEARLDGFQVMPMAEAACRADIIISVTGCKDVVREEHF
                     RTVKDGCVLGNSGHFDNEVSKKALESMCSHKEKVREHVDRYDLKDGRKVYLVAEGRLM
                     NLAAGQGHPVEIMDMSFSIQALALEHLVRNHSKMEPRVYPVPAEMDELVARIKLRTMG
                     ISIDTLSAEQVRYLGDWQEGTQ"
     gene            complement(8933..9694)
                     /locus_tag="PKM11_04555"
     CDS             complement(8933..9694)
                     /locus_tag="PKM11_04555"
                     /inference="COORDINATES: protein motif:HMM:NF010324.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate/pantothenate synthetase"
                     /protein_id="HNX47812.1"
                     /translation="MKISKDHPRYRSLVTRERMAAMVDDGIVSTTGLIAHGRGEAFDY
                     LLGEVTVPEADLAERTAAALLLSAKRPVITINGNAAALAAKELGDLARATGAQIEINL
                     FHRSEERLMKVCDLVERETGLKVLGREQDAVLDGIASERARCTSQGLLSADVVLIPLE
                     DGDRAEAMAKVGKKVISIDLNPLSRTTLAADVAVVDELTRAVPNITRWANGLKGRPQE
                     TKGVLSAFNNQENLAAVMRRMVQGLEKGTADRSER"
     gene            9927..10214
                     /locus_tag="PKM11_04560"
     CDS             9927..10214
                     /locus_tag="PKM11_04560"
                     /inference="COORDINATES: protein motif:HMM:NF016308.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gar1/Naf1 family protein"
                     /protein_id="HNX47813.1"
                     /translation="MQFLGNVQEVTVEGKLVVRATFTPKLKDSVFDNRKRPMGRIVRI
                     FGPVESPYVTVEPTGDTSLLSVTGKQVYIDGVENHGKQKGIGRGNNPVPGV"
     gene            10162..11094
                     /locus_tag="PKM11_04565"
     CDS             10162..11094
                     /locus_tag="PKM11_04565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription initiation factor IIB"
                     /protein_id="HNX47814.1"
                     /translation="MENKKESAEEITRCPECNSGHLVRDYERGELICEECGLVIDDQF
                     IDQGPEWRAFDVEQGEKRARTGAPMTYTIHDKGLSTEISWKNKDSYGKSIPTRNRAQL
                     YRLRKWQRRIRVSNATERNLAFALSELDRMASAMGLPRNVRETAAMVYRKAVNKNLIR
                     GRSIEGVVAASLYAACRQCNVPRTLDEVAGSSRVGRKEIGRTYRFMTRELSLKLMPTK
                     PQDYVQRFCSELKLSGDVQAKAADILKDANKKELTSGRGPTGVAAAAIYIASILCNER
                     RTQREVADIAGVTEVTIRNRYKELTDKLGIEIQL"
     gene            11163..12095
                     /locus_tag="PKM11_04570"
     CDS             11163..12095
                     /locus_tag="PKM11_04570"
                     /inference="COORDINATES: protein motif:HMM:NF024183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX47815.1"
                     /translation="MKVKKPVLLLPAIGLIFAGLILIISPATAIFIFKSVGTVFGIVL
                     MLLFAVVGIWEISLSRTIASSQVGEWPGIMKALIIAVILRLIALFLTADLVQLLNIVA
                     LGLEVLAIVLVYVYRPSFMPNQEEVAAALKRFSTVAVKTSAHCPKCKSVVEADWTLCP
                     DCGTRLPKYCAKCNTKVMENETFCSKCGNKIEVPASLLLTVETLRKTAEMDAAPETRS
                     ARYARLGDGLLKVGQLDEAVEAFRTAIHYTNFDRKRTNFMVKMAVVMANKGSIAEADQ
                     LLDAALKLDPQDVSGAQKVMAELHKAPDANTGPA"
     gene            complement(12092..13135)
                     /gene="endA"
                     /locus_tag="PKM11_04575"
     CDS             complement(12092..13135)
                     /gene="endA"
                     /locus_tag="PKM11_04575"
                     /EC_number="4.6.1.16"
                     /inference="COORDINATES: protein motif:HMM:TIGR00324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000214 - tRNA-intron endonuclease
                     complex [Evidence IEA];
                     GO_function: GO:0000213 - tRNA-intron endonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006388 - tRNA splicing, via
                     endonucleolytic cleavage and ligation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-intron lyase"
                     /protein_id="HNX47816.1"
                     /translation="MAGELLGESVVISDMAEGSQVYNKGFYGYPRPGGGLDLDLLEAL
                     FLLECDKLQVLQNGKPMDHASLYRRAARSVEDLQTRYVVYRDLRQRGYIVKLDQGDFH
                     FRVYERGSSPHNSQAKNWVLAISERDVFNIAALLEKSETSQRTRKDLLLGVVDEEGDI
                     TFYTVEGAEPRGNTEQSPTTAEGALLDDSVIVLGEDADRLYENGFYGKKIGPMLQLSL
                     LETAYLMDKGRLEVRSIRSGQKMGDKGFLTTARRSQPDFDMRMKAYQDLRSRGMVVKT
                     GFKYGTHFRVYEGNPSKHHSRYLVHVVPDDYSTVWAEISRAVRLAHGVKKEILFASSG
                     EQLSYVKLTRVRP"
     gene            13245..13862
                     /locus_tag="PKM11_04580"
     CDS             13245..13862
                     /locus_tag="PKM11_04580"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX47817.1"
                     /translation="MDELDVLLSVIENPTRRRILEALVREPHYPLQLSRELGLSQQGI
                     MKHLRMLEDLDLVRSFLEDSDQGGPSRRRYFPTTGFTMMVDIGPGLFSTEVASRPFEE
                     QGGERESDGRRLLDLRKDLGDIDMELRRLKERRGELIAEKERILEEAGRAVESSSMDY
                     QSRKIVYEYVLHPQISPQDLARGLGLRDDTVEKLIDKLEGESDAK"
     gene            13852..14145
                     /locus_tag="PKM11_04585"
     CDS             13852..14145
                     /locus_tag="PKM11_04585"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47818.1"
                     /translation="MPSEFERYLLEIRKVREDLEKAMRSAAQDLDRLGREVLSDTVTN
                     ARQGGKEAEEALLRLEKDLQEGGPNLRREMDLLLKRLNDAALRVEHELDRREK"
     gene            14226..14699
                     /locus_tag="PKM11_04590"
     CDS             14226..14699
                     /locus_tag="PKM11_04590"
                     /inference="COORDINATES: protein motif:HMM:NF012241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HNX47819.1"
                     /translation="MTGTEREPMDLVPWAWGPVSVFEEMERMLNGMRSGLVRPGNDIF
                     HQEGARLPNMDLREEKDRFLVQAELPGMTKEDVVIEREGDVLGITARKEQDIEEKRDG
                     YIRRERGSMHFHRQMRLPENVDRDRIKARMENGILEVSLPKMSEGTERKKKIEVE"
     gene            14728..16911
                     /locus_tag="PKM11_04595"
     CDS             14728..16911
                     /locus_tag="PKM11_04595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDC48 family AAA ATPase"
                     /protein_id="HNX47820.1"
                     /translation="MSASDKVLKVSEAKSKDAGRGIARVDPAVMEALGLNAGDVVQIE
                     GKKKTVAVVWPGYNEDANRGVVRIDGTIRRNAQTSIDEKVAMRKVAVKPAQKMTFAPT
                     EELRIMGGEEYLAQMMEGRVFSRGDVVELNVMGRRIDLVVMSHAPSSDAVLLNRDTEI
                     KLSDKPAKEAPSGIPKVTYEDIGGLGDEVKKVREMIELPLRHPELFERLGVEAPKGVL
                     LHGPPGTGKTLLAKAVAGETSANFVSIGGPEIMSKFYGESEERLREIFKQAEENAPSI
                     IFIDEIDSIAPKRDEVSGEMERRIVAQLLALMDGLQARGKVVVIGATNRPNALDPALR
                     RPGRFDREIEINIPNRGGRLDVLQIHTRGMPLAEDVDLERLADLTHGYAGADLAALCK
                     EAAMHSLRRILPDLDMEADSIPVEVLNRITVTKDDFFAALREMSPSSLREVLVESPNM
                     HWDDIGGLEDVKAELKEAVEWPLKYAGLFEHMSAEPPKGVLLYGPPGTGKTMLAKAVA
                     TESESNFISIKGPEFLSKWVGESEKAVRETFRKARQAAPCIVFMDEIDSIAPTRGGDS
                     DSHVTERVISQLLTELDGLESLHNVVVIAATNRPDIIDPALLRPGRFDRLIQVGAPDL
                     ETRKAILQVHFKRKPLADDVKLDEVAHKTDGYTGADLAAIANEAVMSAIREAVAAGKG
                     EDPEAMKNTKVNMKHVMDAVEKHRPIPLQELSKFQKIAKDFEYVR"
     gene            16916..17419
                     /locus_tag="PKM11_04600"
     CDS             16916..17419
                     /locus_tag="PKM11_04600"
                     /inference="COORDINATES: protein motif:HMM:NF012241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HNX47821.1"
                     /translation="MRSVRRDDDWNDLFRSFDDDFDVMRERMDRLFEAALRGTGEDPL
                     VYGFSMRTGADGRPMVQEFGNVPRGGAPPDPSCREPLTDVTEEGEKVRVIVELPGVDR
                     DDIDLRSEDSELTISVDTERKKFCKQLDLPCDVRPDSATAEYRNGVLTVLMDKAIRPR
                     GKKIAIN"
     gene            17486..18445
                     /locus_tag="PKM11_04605"
     CDS             17486..18445
                     /locus_tag="PKM11_04605"
                     /inference="COORDINATES: protein motif:HMM:NF003162.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HNX47822.1"
                     /translation="MQRDELIRSVRELLLRSGFSASSPLKLRSIAFDIVARRDRNLIL
                     VKVLTNIDAFSKENAEELKVLAEALGGSIMMIGERSGSGDLEQGIVYSRFDIPIIAFA
                     TMKDLLLDDEPPFIFAAPGGLYVRLDSDLLHNLREDRSVSLGTLAEVAGVSRRTIQMY
                     EAGMGAMIDAALRLEEFLGKQIVVPVDPMGYKPPTQERRPLDMEKCDDFSKNIYTLLM
                     QMGLLVKPTEKCPFEALTVDHDLLILTGLGKDETKLADKAKVVSDISRITGKESVIFI
                     ERLRTRHSIEGTALIGRDELKNIHESERLRKMVNARSEVDERD"
     gene            18432..19052
                     /locus_tag="PKM11_04610"
     CDS             18432..19052
                     /locus_tag="PKM11_04610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47823.1"
                     /translation="MREIELNGSRTYVLPVIKGLVSEGEKVRAAIVELRPEAVGISIS
                     KEELQGLRSYQDEEIELSDQEEAYKAGLLEFGEVQMPPPCYREALKVCDELGVPLIPL
                     DMNEDLFSERYCELIGGLELMKESFFSHRVARKRFDLESAEAFVLDYDRKVNGGRGLS
                     ALNLEREAHMASTAAEMALGRRTLLLLLELERSDGVLRRMEADARD"
     gene            19077..20741
                     /locus_tag="PKM11_04615"
     CDS             19077..20741
                     /locus_tag="PKM11_04615"
                     /inference="COORDINATES: protein motif:HMM:NF013226.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiA family prenyltransferase"
                     /protein_id="HNX47824.1"
                     /translation="MEGDGRSIGRFERKVDSLLAFLEKDRLNLWQTFAYVLIIALARD
                     LSEYYLLDEAFVSTAHPWIFSIAHHVAFFALTYLGLVLILKVFSGSGLRKCLNYTNWY
                     YWIILLPPFVDRFLFGQETNYAYFSWTDFLAAFFLMEGDSFHPGQAVEVLVVLFALFA
                     YVIWLYRDEVQDLPGRAMLALRLGLMALFTVAAMFTLGTPGAYMPVGSEGGVPVFPNF
                     DSTRYVQHHLFIFAYYYLAGTVLVLALSFIALRDRFRRELAALRPYQTAFFALIVLAG
                     TAMAWQDWGEVRLVTSILERPYWVNLAYVIPTVLSAILAWQASVIWNDLSDREHDSPF
                     KKGRVVASGLLPAKEFREASLILAFVALAVSLLLSVQQFLLMAGILVLAFVYSFPPVR
                     FKNALLSPLLMGAGTFLAFLYGASTPFSEVRYVINTPYLTGAVVYPALYTGAFIVGAF
                     MFIGLVIGSIITDADGYEEDRAGGVRTIYTTYGLEKGADMVSVLIFLAALTPLALFSS
                     WTDVIAFPLLGLAASLRFRKKRSSRAVMPIAMVGLLYAALRFLGAF"
     gene            complement(20738..21898)
                     /locus_tag="PKM11_04620"
     CDS             complement(20738..21898)
                     /locus_tag="PKM11_04620"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013646.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HNX47825.1"
                     /translation="MAISGGGPVGSYCAYRCAQAGLSTVLIERQLPPWIKTCAGGVLM
                     RAASRLDFPIPDSVIEKEVKGFHVVGRDFRERFRFDRCLTYTVDRANFDLHLLRMAEK
                     AGVEVRLGKAVERISGSDEVELSTADGKISARCAVIAEGAGSRNARALFGPPPTNSMA
                     MGLRSVDTTMNDPGDDIEVFLIDTPTKGLRRYPMFPLMGWMFPYRGRANFGVGGHGYT
                     KELLLSGMSTVWDDSLAKAVDRSKPSAHPIPILPRERFSSSRFMLAGDSAGLVSPMSG
                     EGLSHGLASAILASDAAISLVKGDDRNAISRYDRLVKDTVVRDIRAATVISPVLHWLL
                     GVVDTRAFFETVRQEGPYVEAWTKMALGEETWQRLLMMTIPRFHRLLFRSLV"
     gene            complement(21921..26117)
                     /locus_tag="PKM11_04625"
     CDS             complement(21921..26117)
                     /locus_tag="PKM11_04625"
                     /inference="COORDINATES: protein motif:HMM:NF019407.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin"
                     /protein_id="HNX47826.1"
                     /translation="MVRFQKQLRKCRRAVSDIIGNLLILAITVTLFSSIMFYVATIPS
                     PEEQTYAEIDYELSEVVDGARWISLTHKGGQPLDNQSTNIYLFTYGTNLISLKMNSSS
                     NPLGTTWTPGEVWKYKIEGINTDTPLSVVIIDTVHNSKVWEAEMIGGQVTGSYAPIIT
                     SRGTKPSIIIDGSSFRFSAAVMDPDGNLNTSSVMVDARSIGLNFVQLTDPDNDGVFTS
                     DPIVGKIAYDDKLVMVMAKDMTDKSASSRFTLVAQYAGGGGSQTNNTQIGPFYDYESY
                     LVNGTYPPDASGGQSGGPVGTTFYYIRRASDNNISRSFTPGEKFYIEIYSDKLVNLAI
                     ENSFSLYNPTTGALLAPPSKLINAFSYGGIYATFHRYYINLSAPMQPLYFPLQISLRD
                     NTGTVVNIPDSISVTGAQYPIIKTYKVNSANQLELCKSFNHTDIMYLKIFTKDVDSNI
                     TRVVINDIQVNDYTGKYVIKQTLPTPTTWMSGAAPTLTKNAPLSQIYKTSKTGTSPSR
                     IYDSVVIDAVYTVQIKLLEPNNDWWLAGRNSYSMLIPVLTDSGNYGTGETYYNLNYQF
                     NVTAPRSTTDMVASVGAGSFTWSASGATWEDNKLVWYKNGERFDQWDATYIDQDTYNG
                     PTGMVLADIDNDGYQDVVVGYQDSTVSLAWYRNQNFAGSAWSTLPYIICTAFDAYPGT
                     QAAENNDKGLANEDSSVWATSYSNDRFAASSYSAINEVVGALGSGDFDGDGDTDIVAS
                     FLHAVVYTSATGSGDASYANSFGMFFNRGIYVFWNDGSWTKTQLSGTNTYTNQNDNPG
                     AMDIAVDDLNQDGVDDIVAVYETGVTKIWINQWRQVIGITTNPKAGSFGPGAVIPAAN
                     IPTVESTNPWDHTQRTPSVAISDVDLNGYPDIIRTSTAAPDSDTKVKVTVIKTMPSTP
                     SDTLKTPSAEYSLENETSAKRTGTMANLVFNDNVYETLTETYKNTSMLFGLADQKQAS
                     SPNPDNTGQDINNLKYDDGVTYNVDSGTTMHVRSFAMDSTYSTKPITQVILRVQYSAT
                     AGYNGNNYIKYSLNGTTFFNTNMLPTSSSLDVNQTFDLKAAGIDTWSELQSLRVMFVH
                     NGTSGTVQFDYARLELKYAESRWMEWVYEVPNLATQVTHQMGISAYTTGEKFNVQYST
                     DRNIWYDAFNFTETTETLKQLQLPHTTNAVYYIKVSAADRSLTDVFNDSLVLDIVGIR
                     HISPTVNWPAKLSILFKMQNNNEFITALAVGDVTSATDMPDNYPDIIVGTSYLGSGAT
                     DRSLMYSYGVGGNSFSPALSITTSSLSAAVGGNNPIYNVQTLALGDFNGDGYTDIALV
                     IGFAPGRSGGTAPSIWLYRNDPTVHQWGEQVLNALASGESAINVKAGNVDLTILYPLL
                     GVLGLVAAEGWINRKDRKRR"
     gene            complement(26206..26733)
                     /gene="cobO"
                     /locus_tag="PKM11_04630"
     CDS             complement(26206..26733)
                     /gene="cobO"
                     /locus_tag="PKM11_04630"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HNX47827.1"
                     /translation="MEKNGLGLLQVYTGDGKGKTTAALGLALRAWGHGLRVGVVQFMK
                     KGEDYGEILALRRMGVEVFQFGSGKLITKGRHCQDDVDCAKRALDLSRSMLGSGEYDL
                     LVLDEVNVALYFGLISLEEVIGALRDREGGVEVVCTGRNAPDELKQEADLVTVMTVEK
                     HPYDEGLVARKGIEF"
     gene            26794..27312
                     /gene="cyaB"
                     /locus_tag="PKM11_04635"
     CDS             26794..27312
                     /gene="cyaB"
                     /locus_tag="PKM11_04635"
                     /inference="COORDINATES: protein motif:HMM:TIGR00318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IV adenylate cyclase"
                     /protein_id="HNX47828.1"
                     /translation="MMELEIKVPCEDLIGLESRLKGMGASHVEDLDQIDLYFSHPARD
                     FGVTDEALRLRRENERTVITYKGPKLDQDTKLREEIELGVEDLDRMSLVLERMGFRPV
                     IRIVKKRTVYDLQGIHFCLDRLPELGNFVEMEWQGDDLDFGKKRIMELKQKLGLRGNE
                     RRSYLELLIEKR"
     gene            complement(27317..27568)
                     /locus_tag="PKM11_04640"
     CDS             complement(27317..27568)
                     /locus_tag="PKM11_04640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47829.1"
                     /translation="MDDDAPGKNVDFVTLSAEKIPFGRNNFIEVARKKAITQEGENEF
                     ISLSRGYYLPDGTERFKKSVTIPDDPKIKDFVIEKIRTL"
     gene            27742..29001
                     /locus_tag="PKM11_04645"
     CDS             27742..29001
                     /locus_tag="PKM11_04645"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HNX47830.1"
                     /translation="MDGEGPKRTCPRCGAQVPEDAAFCQRCGLPQNGTDDVARQYAFY
                     APPPRPVREKSSLQSAREVIRGIGAYMTLVVLALVTINVGIMLWGMQYVIPEAWDSYT
                     SLFVALPWLVRFLELPGVWFVVYYILLVIAVLLSYAIMLYLGRKQLWNELRFKPSAHS
                     PLYGITTIFLAVLAMNAAYYLLLGLFGIDPSSGGDTGELWQKLYSLLRASVWEEVICR
                     ILYIGLPLGAVYILKGKGAPYHRYVLGGNFQFGPWEKFFLVFSSAMFALAHVFSWDLY
                     KVPPTFLAGLALGYLFLKYGVYASIMLHFFIDYLSFPMDVWPGDGTDMIMGLLMLAFM
                     ALGVVYLAYYFVKALELFSGRQIIKWGDPRPVSVYYQPLSPSAKYVPYDGALTTPSFG
                     FVCKHCAGTEARYVDGKFVCSRCGRES"
     gene            complement(29002..29766)
                     /locus_tag="PKM11_04650"
     CDS             complement(29002..29766)
                     /locus_tag="PKM11_04650"
                     /inference="COORDINATES: protein motif:HMM:NF013429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HNX47831.1"
                     /translation="MIAVSSPHLSRWDFPYALERVAEHYQAWEIVAEGRHLLRDIRDD
                     FLRLSPSYDLEYSVHAPLSDINIGAINPRMRAAALNEVLESMEIAHRMGIDLVTVHPG
                     FLSPLTALDRDTAIQATKESLKAIDARGKDLGVRIALENMPEMPVAMAKGPEELLLFM
                     EGTDLGVCFDIGHSNTVGNIPDFQSIKDRFMNMHVHDNLGDRDRHMVIGEGNIDFPRW
                     LSAFRPYHGRYVIEARELERSLVSRDRLRGMLSSLD"
     gene            complement(29763..30146)
                     /locus_tag="PKM11_04655"
     CDS             complement(29763..30146)
                     /locus_tag="PKM11_04655"
                     /inference="COORDINATES: protein motif:HMM:NF013994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding domain-containing protein"
                     /protein_id="HNX47832.1"
                     /translation="MVEVVASARWYPTEDGERVRSSLLNIFPGAVLEEGQGTIRAKTD
                     DMSRFKEIIRNHRILDSTRAVMLRGTSEEGIRFQMNKQAAFVGKISFVEGNAPLGHIE
                     VLIKGTELEAFIDNVAPQTIDGEIP"
     gene            30202..>30777
                     /locus_tag="PKM11_04660"
     CDS             30202..>30777
                     /locus_tag="PKM11_04660"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47833.1"
                     /translation="MRSKVVEALANDGYLLDQEAEEFILSQPSPLQFARQFIPQIPYQ
                     PLVVTLRDLRTVVHVDAPRLETIVRPEPVSVRRIGEVRVMKDITAQSDCLGTVEGFAR
                     YFQDRFANLKALLLRRRDMMGAISVQRAMDPNKLQADEVKVIGMVNEVRDTRSGEKII
                     ELEDETGRMTVMVPKDNKAAKDSILQDEVIGV"
BASE COUNT         6012 a         9149 c         9433 g         6183 t
ORIGIN      
        1 tggacccccg ggggaaggtc ccggagaacg ccttggtgct agatgcccgg gcaaggacgc
       61 tggtggtcac cctggaggac tgcgcccggc aatatccggg agcggagacg gtccgtctgg
      121 gcaagggcgc catcgacctc caggcgctgc tcgatgagct tggaaggaga ggagtgtcca
      181 ccctactggt ggagggagga ggggagacca tccactcctt cttcaaggcc ggactggtgg
      241 acgtctactc ggtctttgtc ggcgatttca tcatcggcgg cagggaatcc cccaccccgg
      301 tggacggaga aggattccgg atgggcgagc acgtccagct gcgtttggta tcggtcgagc
      361 gcctgggctt tggcgtgcac ctcacctacg aggtatggcg ggatgactga gccctccttc
      421 ctattggacg gcatgctggg atccctggcc cgctggctga ggataatggg ctatgattcc
      481 gtctacatgc ggaacgagga tgatctcact ttactctcca ttcgcggcga ccgatacctt
      541 ctgaccaggg accgccagct ggcgcagcgc gccgggtccc aagggctatt catcgagagc
      601 gacaaactgg acgttcagct ctccgccgtg gtcaagaggt tcgacctgcg cttcgacatc
      661 caacgcacgc gctgcacggc ctgcaacggt cgtttggaga aggtggccaa agagctgatc
      721 aaggaccggg tggccgcggg aacctacgac gagattcagg agttctggat gtgccagggg
      781 tgcggcaagg ttttctggca tggcgcccat tggaagaaca tcggccaccg actggacggg
      841 ctcagctgat gtcccggaaa taatcctcgc tgagaacctt accattgctg gcgtcgatga
      901 tcatgacgcc cttggtgcct tccacgcacc agatcgggac gtaatagatg cccagaggtc
      961 tcacggaccc caggtccagg cggggatgca ccgtcaccct ctcggtcatg gtcacctgcc
     1021 cgttctccct gatcatatcc ctatcgtacg tatgctccct ctccacggtc gtgcggacca
     1081 gggcggtggc gtcctcctcc tccagcaccg gctccaggcg cttgtacccc tggtccaggt
     1141 tggtgactgt ctccgggacc tggtcccagg gctgcacgcc cttggtcagg gcgttcacgg
     1201 ccatgttgcc ctcccggccg ccgaccttcc cctcgccgac gaacaacgga acctggtagg
     1261 cgaaaacata gtgcgggacc agctccagac gttggctgta gccgcccacg gtcttggagg
     1321 tgagctccac cacctcctgc agagagatgc gcattgggag tatacgctcc tcgcccaccc
     1381 cggaatggtc gtcgtccagc atcgggacgt cgtccgcgta gagatcgtca atcagaccgt
     1441 ggtcctcctc ccccaccagc ttctcgatgc gggtgcgccc tatctcgtgc tccaccgcct
     1501 cgcggtccca taccaccaac cccgggggta gggcggccag ggtcgactcc gccagcggaa
     1561 cgagtgccgc caggaccacc ttgcccttgg tgaccggggc ggtcttgacc agctcctcca
     1621 tggccgccgg ggaatgcctt acatagggaa agaaatgaag ctctatgtta tcgcggcgcc
     1681 cgcgcacgaa ggggccgacc tggtccacca ggaagcctct cgtttccaat atctccttga
     1741 gcaccgcgtt caatgtggtc atgctgggaa caggaatcgc cgcttgcgca ttaatagctt
     1801 atcgggcgtc ctcccaaagg tcgcgtccgg tacaggcctc cgttcctaga agccccatga
     1861 actcctcggg gtatggttcg aagaggacct gctgtaaaag gtattcctcc cccttcctca
     1921 gggcccagga gcggaccatc agcagcggcg cggtcagcgg cacctttccc tcggcgtacc
     1981 attccaggga gcgcaggaag tgctgcttct ccttgacgtc cagctcgtcc gagaagtagc
     2041 ccatggcgtg catcagcacg ttgttccagg agcgacagct cggcggccgg cgaagagcgt
     2101 tgtgaagctc caccgaataa tcctgtaggc gctcctcgat gggagcctgg gaggccgtta
     2161 tacggcccaa tcggcgcatg gccgcctggc tgtatcccat taacaacagc ttgtgcctgg
     2221 cgtggaagtc catgagcgcc ttggaggttc ccttctcccg acatcctcgg aaccgggcgg
     2281 aggtgaagat gcgggtgagg aagtgatcgg cgatccttcc gttcagcaaa cgggcctcgt
     2341 cctccaatgc cagatgagga aaggcgctca tcacctcccg ggcgaatatt ccggccgatt
     2401 ttccggtgag caccgccttt ccctcgcccg gcgggtacac ccgaacgtcc tttatgccgc
     2461 aggaggggga gcggttcttg agcagaaacc catccacgtc cctcaggttg gccagatgct
     2521 ccctggtgaa gcgcaaagcc gtttccgtca catcccttcc ggtgctgggc tgcatcagat
     2581 ggtcctctcc gtccaggcgc actatgcgga ccgggtccct tggaacgcca agacccatgt
     2641 ccgcctccat gcacactggc aagaactcca cgtagggcat gagacgcagt aggaactcgc
     2701 tcttgatcat cgcgccgttg tagcggcagg cctcgaattc gatgcagcgg cttaccacca
     2761 cccggggttt gggatcgggc atgaggtcct caaggaacag gtaagtaaaa aatggtatgg
     2821 acggatgata cttcgtgaga cgggaatggc tatgggtcgc gatcgtagcg ctcctgctat
     2881 cctccgtggc cctgggatgg atggcctggg agaaggggga ggtcgagctg tacctctttc
     2941 ttatatttcc ggtgctgaag gcggacggcg tctacggggc ggcggcattg ctcctggcct
     3001 tcgcgacgat ggtattggtc cttttcgccc tcttcgcctg gagatcgccc gatgatacga
     3061 aaccggagag aggaacgtcc gtgggaggag tgatcatgat aggcccgata ccgatcgtgc
     3121 tgggcagcga ccggcggacc acgatcatag ctctgatcct ggccctggtc gtcctgatga
     3181 tcatcatcct actgctggtc cagtaaggcc ttggccgcca tccagggatc cagcttatcc
     3241 tttcgggata gcaccctcac ggcctccatg atgtccagat aatcctggta ccgcagcccc
     3301 gcccggcgcg cctcgcggct gactgcgttc tccaccgtat cgtcccggcg cctcttgtcc
     3361 agagcgtccg cgagcacctt cttcagccct tcgttcagcg gttccattcc tccaccgcct
     3421 tcaagaagtt acggaatatg tccatgccga aatcggtgtt ctccacctcg ggatggaact
     3481 gcacggcgta caacggccgg cgcagggagc gcatcgcttc caccagacag gtgtcggagt
     3541 gcgcgagcac ctcgaagccg tccggaacga ccttgacctc gtcgttgtgc gattcccaga
     3601 catcgaactc gcggggaacg ccttggaaca gatggtcctc ctggtccacg tagagacggg
     3661 cccggccgaa ctcggcgcgg accgccgggc ctgtgctacc gccataatga gtggccatga
     3721 actgcatgcc ggcgcatatg cctagcacgg gaaaatcggc cttgtccaga tattcgccgt
     3781 tattgcccat gcgcccggcc tccgaggcca cgtccggcgc acctccagag agcaccaggg
     3841 catccacctg gcctatctga tcgaaggggg tggtgttggg gattatcttg gtctccacct
     3901 tgagatactt cagaacccgc cactcgcggt gggtccactg tcccccgttg tccaccacgt
     3961 agacccgcat cgagcccgaa tcaccgattt gcggtataaa acgattggtc ggacccccgg
     4021 aagcgtcccg ggaaacgatt atgtctggca tttgcattac gaatcaacat gaaggccgtg
     4081 atattcgatc tgggccacac actgatcgac tactaccacg actgggccgg tccagaggag
     4141 cggatagtca gccggctgta ccgcctggcc gcggagaccg ggggtggctt gccggagccg
     4201 gagttccgcc gttcggtgct ggcgaccctg caggggaacc gggaacgcaa gctgcaggac
     4261 atgctggaga tccccctgga gactgtgctg gaccggttgt tcagctccgc cggttgccag
     4321 gtggacgagg gcctggtcca ggaaggcatg gagatattct accaggcgct caaggaggac
     4381 cgcagcctgg tgcctggaac gttggagatg ctgcaacgag tgcgcgaccg gggctgctcg
     4441 ataggcctca tctccgacgt ggcctggggg ctgccctcgg aatacccgct ccgggacatg
     4501 aagcacttcg gcctggacgg ttattttgac gacctgctct tttcgagcga tgtcggtctc
     4561 cgaaaaccga acccccgcct gttcaagatg gccatgttca atctgggcgc cgaccgtgac
     4621 ggatcgatgt acgtcgggaa ctccctgcag gcggacatca agggagccaa gtcggtgggc
     4681 atgaaggcgg ttctgaagaa aagcggctac ttccagccgg acgattcgat cgtcccggat
     4741 cacaccgtcg acgactggaa ggaacttgac gagctggtgt gatcactccc actcgatggt
     4801 cgccggcggc ttgtgcgtga cgtcgtacac cacgcggttc acgttggcct tcatctcgtt
     4861 ggtgatgcgc agggagatgc gctccagcac gtcgtacggg atctttgaga aggaggcggt
     4921 catggcgtcc accgactcca cggagcggat ggcgaccgtt ctcccgtagg cccggcggtc
     4981 cccctgcacg cccaccgact gcaccggaag gagtaccgcg aagtactgcc aggggcggac
     5041 catgcttcct ttatccgagg cggcctccag ctcctcctcc actatggcgc aggcctcgcg
     5101 aaccacgctc accgactccg gggtgacctc cccgatgacc ctgatggcca gggccggacc
     5161 ggggaagggc tggcgttcgg agacctccac gcccaggaag cgggccacgg cgcgcacctc
     5221 gtccttgtag aggtcccaca gtggctccac cagcttgagg gtcatgtcct tgggcagccc
     5281 gccgacattg tgatggctct tgatggtgtc ccgtacgccg tcaccgctct cgatccaatc
     5341 cggagcgatg gttccctgca ccaggtggtc cgcgccgaac gccagggcct cccgctcgaa
     5401 caccctgatg aacttctccc cgatggcctt gcgcttggcc tccggatcta tctgcccctt
     5461 gagggcggcg aagaactcgt ccttggcgtc gactaggcgg taatggacgt ttagattgtc
     5521 gaacatgcgg cgcacgtcct cggtctctcc ctggcgcata agaccggtgt ccacgtatac
     5581 cgttaggaga cgttcgccaa tggcccggtc gaccaggacc gcggccacgg tgctatcgac
     5641 gcctccggag caggcgatga tggccttgcc ggtgatcttg gtcctcagtt cctcgatctt
     5701 ctcctttacg aactcttggg ggtcgaacat caggcttgca cctcgttgga atcgctctcc
     5761 accttctcgg ccatctcctg gcgataggag gatagcgcct gggccagttt ggggtccccg
     5821 atggagagta tggagaccgc cagcaacgcc gcgttgtccc cgcggtccag gcccacgcag
     5881 gccaccggga tgccgggggg catctgaact atggacaata tggaatcaag gcccagcttt
     5941 ccggacaccg gaaccccgat aacgggcttg caggtgaagg acgccaccgc cccagggagg
     6001 gccgcggcca acccggccac ggcaatgaac acgtccgcct tgctgcggtc caccatcagc
     6061 ttcacccggt ccggggtgcg gtgggcggag gccactatca tttccgcctc gacgccgaag
     6121 cgcttgagaa catccagggc cttgcgcccc acttccacgt cgctcttgct cccgagaatg
     6181 atgagaaccg aagccattgg gtcactgaca gagttcaaat aaaaaaggat ttgcctcccg
     6241 aggagacaag gaaagggatg ttaagggatt tcagctcttc atgatggcca gcaggaacgc
     6301 gccgacggcc accagggcgc cgatcagggc ggccaggatg ttgacgaagg cgacccatac
     6361 cacttcagat atgtcgacct cgacaccggc catgtccgcg tatcccaggt atccccagac
     6421 cacgccgacg agcagtccaa caaccagcag aacgacacct atcatcctgc tcttgccgct
     6481 tccgaaatag gccgtgaagg ctccagccag tatcattacc aggctgaagg tcagcaggag
     6541 caccgtcagg aattgcatca gatccattct tgatcacctt tagttgatat ccatcctagg
     6601 atcggtgtcg acgagcagat gtcggcgcca ccagcctcga tgccgagcgc ggcatgatgg
     6661 cttggaaggc gccctgcacc attcgttcac ctagggagtc ctacaagttt tttcacttat
     6721 tataattttg ctccgatcgc acgcccggtc cccggatgtc cagatatctc atcgccgcaa
     6781 ggaccgcgcc ctctcctcca ccattcccca gtcggggatg gaggttaggg aacctggtga
     6841 tgacaccacg aacgaagcgg cggcgctgcc caggacccca cattccagcc agctcttgcc
     6901 ccggtacagt ccggcgtaga acccggcccg gaaggcgtcc ccggctccgg tggggtccac
     6961 cacctcgacc ttggccgccg gaacgtccag aacctcgttc cggccgtata tcctggcccc
     7021 ttggccgccc aaggtgttga cgatcacctg cattccccga tagctgtcca ggacatcttc
     7081 cgggctatcc ttgccggtgt agcgcagggc ggtggccagc tcgttgcggt tgcagaacag
     7141 catgtccgtg aagtccaagg ccttctggaa acgctcggcg tcccacacgt ggtggatctc
     7201 ctgcgccggg tccagcccac gcctcttgcg cagcagattg ggtcgcgcca gtagcttcag
     7261 gtagtaatcg ggggaaccgg tcatcagatg tatcgccaga gcgtccttgg cccccttgac
     7321 ctggatggga taggagccca tgttggccat ggccccctgg aacacgtacg ccacctggtc
     7381 ctccttctcg tcggtggcta tccataccgt gggcgtctcc tgcccgtcca cctccaccag
     7441 ttcgtccagt atgaccccgt tggactccat cagccttcgg aactccggag gcaggtcctt
     7501 acccacgtac gagaccaggg cagttgggac gccaagagcg gaggccatgg tggccaggtt
     7561 ggcgcccgtg cccccgaaat agctcttctt gctgatgacg ttggaggagg tgttgcgctc
     7621 cggaaggtcc ttcagagcga gcagatgatc gatgttggtg tggccataaa cgcacaggaa
     7681 aggcctcact gggtaccctc ctgccaatcg ccaaggtacc gcacctgctc cgcggagagc
     7741 gtgtctatgg agatgcccat ggtccggagc ttgatcctag cgaccagctc atccatctcc
     7801 gccgggaccg gatagacccg gggctccatc ttggaatggt tgcgcaccag gtgctctagc
     7861 gccaacgcct ggatggagaa gctcatgtcc attatctcca ccgggtgtcc ctgtccggcg
     7921 gccaggttca tcaggcggcc ttcggccacc aggtacacct tgcgcccgtc cttcaggtcg
     7981 tagcggtcca cgtgctccct gaccttctcc ttgtgagagc acatggattc cagggccttc
     8041 ttggagacct cgttgtcgaa gtgccccgag ttcccgagga cgcagccgtc cttcacggta
     8101 cggaagtgct cctcccggac cacgtccttg cagccggtga cggatattat tatatcggcc
     8161 cgacaggccg cctcggccat gggcatgacc tggaacccgt ccagacgagc ctcgatggcc
     8221 cgtatcggat cgacctccgt gactatgact atcgccccca tgcccttggc ccgcatggcc
     8281 acgccccgtc cgcaccagcc gtagccggcc acgacaagcg tcttgccggc gatgagcagg
     8341 ttggtggcgt tcatgaaccc gtcgaaggtg ctctggcccg tcccgtagcg gttgtcgaac
     8401 aggtacttca tcttggcgtc gttcacggcc atgaccggga atttgagctt gccgtcggcg
     8461 gccatggcct ggagacggat caccccggtg gtggtctcct cgttcccgcc cttcacctcg
     8521 tccagctgtt cccgccggga ggtgtggagc atggttatga ggtccgcccc atcatcgatg
     8581 acgaactccg gccgcatgtc cagcacggcg ttgaggttct cgtagtactc cttgttgctc
     8641 tcgcccttcc tggcgaagac ctctatgccc cgctcctcct tgagcgcaag cgccaccgag
     8701 tcatccgtgg acagggggtt gcagcttgcc aaccgcaccc gggccccggc ccgggccaga
     8761 gttaccgcca gcatgccggt cttggcctcc acgtgcaggg ccatgcccac cttcgttcct
     8821 ttgagggagc cttcctggcg catcctctcc cccacctctc gtatcaccga catatgggcc
     8881 tccgcccaac ccaggcggcg agatcccttc aacagcagtt ctttgtccat gttcatcgct
     8941 ccgatcgatc agcggtacct ttctccagtc cctggaccat gcgccgcatc acggcggcca
     9001 ggttctcctg gttgttgaag gccgacagga cgcccttcgt ctcctgcggc ctacccttga
     9061 gcccattggc ccatctcgtg atgttcggca cggcccgggt tagctcgtcc accaccgcca
     9121 cgtccgccgc aagagtggtt cgtgacaacg ggttcaggtc gatggatatc accttcttcc
     9181 cgaccttggc catggcctcc gcccggtccc cgtcctccag cgggataagc accacatcgg
     9241 cggacagcag cccctggctg gtgcaacggg ccctctccga agcgatacca tccaggaccg
     9301 cgtcctgctc ccggcccagg accttcaatc ccgtttccct ctccaccaga tcgcagacct
     9361 tcatcaggcg ctcctcgctg cggtggaaca ggttgatctc gatctgcgcc ccggtggccc
     9421 gggccaggtc ccccagctcc ttggcggcca aggcggccgc gttgccgttg atggtgatga
     9481 ccgggcgctt cgcggacaga agcagggccg cggcggtcct ttctgccagg tcggcctcgg
     9541 gaaccgtgac ctcgcccagc aagtaatcga aggcctcgcc cctaccgtgg gcgatgagcc
     9601 cggtggtgga cacgatgccg tcatccacca tggcggccat gcgctccctg gtgaccaggg
     9661 aacggtacct ggggtggtcc ttggagatct tcacgcgccg tagagagctt gctctgacat
     9721 aaactgtgtg atggaccgta cgccctagcc tcggggcgct ctgaacggca ccctatgata
     9781 gggttaaata tcatcagaaa caggaaaatc caacaaagct tatatccctt gagccgtcgt
     9841 ataaatatac ctttgcgtaa tgttcaaata gtaaatttat tatcctcttt ctcaacaccg
     9901 gttaatatcg gcgtataggg ttcatcatgc aatttcttgg gaacgtgcag gaagtgaccg
     9961 tggaaggcaa actagtggtg cgcgctacct tcacccccaa gctcaaagat tcggtgttcg
    10021 acaaccgaaa gcggccaatg ggcaggatcg tgaggatctt cggcccggtg gaatctccct
    10081 atgtgaccgt cgaaccgacc ggagacacca gcctgctgtc cgtaaccgga aagcaggtct
    10141 atatcgatgg ggtcgagaac catggaaaac aaaaaggaat cggcagagga aataacccgg
    10201 tgcccggagt gtaacagcgg acacctggtc agggactatg agcggggtga gctgatctgc
    10261 gaggagtgcg gattggttat agacgaccag ttcatagacc aaggcccgga gtggagggcc
    10321 ttcgacgtgg agcaggggga gaagcgcgcc aggaccggtg cgccgatgac ctacaccatc
    10381 cacgataagg gactgtccac cgagatatcc tggaagaaca aggactctta cggcaagagc
    10441 atccccacca ggaaccgcgc ccagctctac cgactacgga agtggcagcg gaggatacgg
    10501 gtatccaacg ccaccgagag gaacctggcc ttcgccctca gcgagctgga ccgcatggcc
    10561 tcggccatgg gactgccccg caacgttcgt gaaacggccg ccatggtata ccgcaaggcg
    10621 gtcaacaaga acctgatccg cggccggagc atcgaaggcg tggtcgccgc ttcgctgtac
    10681 gccgcctgcc ggcagtgcaa cgtgccccgt accttggatg aggtcgccgg ctccagccgg
    10741 gtcggacgca aggagatcgg ccgtacctac cgtttcatga ccagggagct gtccctgaag
    10801 ctcatgccca ccaagcccca ggactatgtg cagaggttct gctccgagct gaagttgagc
    10861 ggggacgtcc aggccaaggc cgcggacatc ctgaaggatg ccaacaagaa ggagctgacc
    10921 tccgggcgcg gtccgaccgg cgtcgccgcg gcggccatct acatcgccag catcctgtgc
    10981 aacgagcgtc gcacccagcg tgaggtggcc gacatcgccg gcgtcaccga ggtcaccata
    11041 cggaaccgct acaaggagct gaccgacaag ttgggcatag agatacagct ctgacccgca
    11101 aacctcttat cttcttaaca ttttagaggg atgcgccctg gcgcctgcga gaggtgaaca
    11161 taatgaaggt gaagaagccc gttctgttgt tgccggccat aggcctgatc ttcgctggac
    11221 tcatcctgat catatcgccg gccacagcga tattcatctt caagtccgtg ggcaccgtgt
    11281 tcggcatcgt actgatgctg ctgttcgccg tggtgggcat ctgggagata tccctgtccc
    11341 gaaccatagc cagcagccag gtgggcgagt ggccggggat tatgaaggct ttgatcatcg
    11401 ccgtgatcct gcggttgatc gctctgttcc taaccgctga cctggtgcag ctgctcaaca
    11461 tagtagcttt gggattggag gtcctggcca tcgtcctggt atacgtttac cggccttcct
    11521 tcatgcccaa tcaggaagag gtggcggccg ccctgaagcg cttctccacg gtggcggtca
    11581 agaccagcgc ccattgcccc aagtgcaagt cagtggtgga agcggactgg acactgtgcc
    11641 ccgattgcgg caccaggctc ccgaagtact gcgccaagtg caacaccaag gtaatggaga
    11701 acgagacctt ctgtagcaag tgcggtaaca agatcgaggt ccccgcctcc ctgctgttga
    11761 cggtggaaac cctgcgcaag accgccgaga tggacgccgc cccggagacc cgctccgccc
    11821 gctacgccag gctcggagac ggcctgctta aggttggaca gctggacgaa gcggtggaag
    11881 cgttcaggac cgccatccac tacaccaact tcgatcgaaa gcgcaccaac ttcatggtca
    11941 agatggccgt ggtcatggcc aacaagggaa gcatcgcgga ggcggaccaa ctgctggacg
    12001 ccgccttgaa gcttgatcct caggacgttt ccggagcgca gaaggtcatg gccgaactgc
    12061 acaaggcgcc cgatgcgaat accggtccgg cctagggccg caccctggtc aattttacgt
    12121 aactgagctg ctcgccggag ctggcgaaca gtatctcctt ctttaccccg tgcgctaaac
    12181 gcaccgcacg ggatatctcc gcccagacgg tggaataatc gtccgggacc acgtgcacca
    12241 ggtaccggga gtgatgtttg gatgggttac cctcgtacac ccggaagtgg gtgccgtact
    12301 tgaagccggt cttgaccacc attccccgcg agcgaaggtc ctggtaggcc ttcatgcgca
    12361 tatcgaaatc gggctgggac cttctggcgg tggtcaagaa tcccttgtcg cccatcttct
    12421 gcccggaccg tatggagcgg acctccagac gtcccttgtc catgaggtac gccgtttcca
    12481 gcaacgacaa ttgcagcatc gggccgatct tcttgccgta gaagccgttc tcgtagagcc
    12541 tatcggcatc ctcccccagg acgatgaccg agtcgtccag tagcgcgccc tcggcggtgg
    12601 tcggagattg ctcggtgttg cctcgcggct cggcgccctc cacggtgtag aaggtgatgt
    12661 ccccctcttc gtccaccacg cccagcagga ggtccttgcg ggtgcgctgc gaggtctcgc
    12721 tcttctccag gagggcggcg atgttgaaga cgtccctctc cgagatcgcc aggacccagt
    12781 tcttggcctg ggagttgtgc ggggacgagc ccctctcgta aacgcggaag tggaagtccc
    12841 cctggtccag cttgactatg taacccctct gtctgagatc gcgatagacg acgtagcggg
    12901 tctgcaggtc ctccacggac cgggcggccc ggcggtacag cgaggcatgg tccatgggct
    12961 tgccgttctg cagcacctgg agcttgtcgc attccagaag gaacagcgcc tccagcaggt
    13021 cgaggtccaa tccgccgccc ggccggggat agccgtaaaa gcccttgttg tagacctggc
    13081 ttccctcggc catgtcggaa atgacaacgc tttcccccag gagctcgccc gccatgccac
    13141 ttgaacgatg tccgttagtt aaagattccc cgctcacgaa ttaattaaat acaaatagtt
    13201 cacaaataca agatgtgaac atctagttca atagatggtg gaacatggac gagcttgacg
    13261 tgcttttatc ggtgatcgag aaccccaccc gccgccggat actggaagcg ttggtgcggg
    13321 agccgcacta tcctctgcag ctgtcccggg agctggggtt gagccagcag ggcatcatga
    13381 aacacctgcg gatgctggag gacctggacc tggtgcggtc cttcctggag gacagcgatc
    13441 agggcggacc ttcccggaga cgatactttc cgaccactgg attcaccatg atggtggaca
    13501 tcggcccggg gctgttcagc accgaggtgg ccagtcggcc cttcgaggag cagggcgggg
    13561 agagggagag cgacggcaga aggctgctgg acctgcgcaa ggacctgggc gatatcgaca
    13621 tggagctgag gcggttgaag gagcgccgcg gtgagctcat agccgagaag gaacgcatcc
    13681 tggaggaggc ggggcgggcg gtcgaatcat cgtcgatgga ctaccagagc cgcaagatcg
    13741 tctacgagta cgtcctgcat ccgcagatca gcccccagga cctggctcgc ggcctaggcc
    13801 tccgggatga cacggtggag aagttgatag ataagctgga gggagagagc gatgccaagt
    13861 gagttcgaac gttatctgtt ggagatcagg aaggtccggg aggacctgga gaaggccatg
    13921 cgctccgcgg cccaggacct ggaccggctg ggccgggaag tgctgagcga cacggtgacc
    13981 aacgccaggc aggggggcaa ggaggcggag gaggcgctgc tgaggctgga gaaggacctc
    14041 caggagggcg gacccaacct acggagggag atggacctgc tgctgaaacg attgaacgac
    14101 gcggcgctcc gggtggaaca cgaactagac cgacgcgaaa aataaattta tatagaagca
    14161 ctaacactga tgtattatac taagagtata caactcttgg ttgatatgtt aagaggtgat
    14221 atgagatgac cggaactgaa agggaaccga tggacctggt cccttgggca tggggccccg
    14281 tctccgtctt cgaggagatg gaacggatgt tgaacggcat gcgttcgggc ctggtgcgcc
    14341 ctggaaatga catcttccat caggaagggg ctcgtctgcc gaacatggac cttcgcgagg
    14401 agaaggaccg attcctggtc caggccgagc ttccagggat gaccaaggag gacgtggtca
    14461 tcgagaggga gggcgacgtg ctcggtatca ccgccagaaa ggaacaggac atcgaggaga
    14521 agagggacgg ctacatccgt cgggaaaggg gaagcatgca cttccaccgc cagatgcgcc
    14581 tcccggagaa cgtggaccgc gaccggataa aggcgaggat ggagaacggg atactggagg
    14641 tctccttgcc caagatgtcc gagggaacgg aaaggaagaa aaagatcgag gtggagtgat
    14701 ctctacctca cctgagagtg ataactgatg agcgcatctg acaaggtttt aaaggtgtcc
    14761 gaggctaagt ccaaggatgc cggacgcggc atagccagag tggacccggc ggtgatggag
    14821 gccctggggc taaacgccgg cgatgtggtc caaatagagg gaaagaagaa gacggtggcc
    14881 gtggtctggc ctggttacaa cgaggatgcc aaccgcggag tggtgcgcat cgatggaacg
    14941 ataaggagga acgcccagac cagcatcgac gagaaggtgg ccatgaggaa ggtcgccgtg
    15001 aaaccagccc agaagatgac cttcgccccg acggaggaac tgcgcatcat gggaggcgag
    15061 gagtacctgg cccagatgat ggaaggccgg gtgttctccc gcggggacgt ggtggagctt
    15121 aacgtcatgg gaaggcgcat cgacctggtg gtcatgtcgc atgcccctag ctccgacgcc
    15181 gttctcctga acagggacac ggagatcaag ctgagcgaca agccggcgaa ggaggccccc
    15241 tccggaatac cgaaggtaac ctacgaggac atcggtggcc tcggcgacga ggtcaagaag
    15301 gtccgggaga tgatcgaact tcctttgcgc catccggagc tgttcgagag attgggggtc
    15361 gaggcgccca agggagtgct gctgcacggc cctccaggca ctggtaagac cttgctggcc
    15421 aaggccgttg ccggggagac cagcgccaat ttcgtgtcca tcggcggacc ggagatcatg
    15481 agcaagttct acggcgagag cgaggaacgc ctgagggaga tattcaagca ggccgaggag
    15541 aacgcgcctt ccatcatctt catagacgag atagattcca tcgcccccaa gagggacgag
    15601 gtgtccgggg aaatggaacg ccgcatagtg gcgcagctgc tggcgctgat ggacggcctg
    15661 caggcccggg gcaaggtcgt ggtcataggc gccaccaacc gcccgaacgc gctagacccg
    15721 gcgctgcgcc ggccgggacg cttcgaccgg gagatagaga tcaacatccc caaccggggc
    15781 ggacgactcg acgtgttgca gatacacacc cgcggcatgc ctctggcgga ggacgtggac
    15841 ctggagcgtt tggcggacct tacgcacggc tacgccgggg cggacctggc cgcgttgtgc
    15901 aaggaggcgg ccatgcattc cctgagacgc atactgccgg acctggacat ggaggcggac
    15961 agcattcccg tggaggtact caaccgcatc acggtgacca aggacgattt ctttgccgcc
    16021 ctacgtgaga tgtccccgtc cagcttgcgc gaggtgctgg tcgagtcacc gaacatgcac
    16081 tgggacgaca taggcgggct ggaggacgtg aaagcggaac tgaaggaggc cgtggaatgg
    16141 cccctgaagt acgccgggct gttcgagcac atgtcggcgg aaccgcccaa gggcgtgctg
    16201 ctgtacggac cacctggaac gggaaagacc atgctggcga aggcggtggc gacggagtca
    16261 gaaagcaact tcatcagcat caaggggccg gagttcctga gcaagtgggt cggcgagagc
    16321 gagaaggcgg tgcgcgagac gttccgcaag gcccgtcagg ccgccccctg catcgtgttc
    16381 atggacgaga tcgattccat agcgcccacg cgcggtggtg attccgattc ccatgtgacg
    16441 gagagggtca tctcccaact gctcaccgag ctggacggcc tggagtcgct gcacaacgtg
    16501 gtggtgatcg cggccacgaa ccgcccggac atcatcgacc cggcgctgct gcgccccggc
    16561 cgcttcgatc ggctgataca ggtgggcgcc ccggacctgg agaccaggaa ggccatcctg
    16621 caggtgcact tcaagcggaa gccgctggct gacgatgtga agctggacga ggtggcgcac
    16681 aagaccgacg ggtacaccgg agcggacctg gcggctatcg ccaacgaggc ggtgatgagc
    16741 gccataaggg aagcggtggc cgcgggaaag ggagaggacc ccgaggccat gaagaacacc
    16801 aaggtgaaca tgaagcacgt gatggacgcg gtggagaagc accgccccat cccccttcag
    16861 gagctgagca agttccagaa gatagccaag gatttcgagt acgtgaggtg atgatatgag
    16921 aagcgtgaga cgtgacgatg attggaacga cctgttccgt tccttcgacg atgatttcga
    16981 cgtgatgcgg gagcgcatgg accggctatt cgaggcggcc ctgcgcggaa ctggggagga
    17041 tccgctggtc tatgggttct cgatgcgcac cggggcggac ggaaggccga tggtgcagga
    17101 gttcgggaac gtaccccggg gcggcgcgcc cccggacccg agctgccggg agccccttac
    17161 tgacgtcaca gaggaaggcg aaaaagtgcg ggtcatagtg gagctgccgg gtgtggacag
    17221 ggatgacatc gaccttcgtt ccgaggatag cgagctcacg atatccgtgg atacggaaag
    17281 aaagaagttc tgcaagcagc tggaccttcc ttgcgacgta cgcccggaca gcgcgaccgc
    17341 cgagtaccgc aatggggtgc tgacggtgct catggacaag gccatacgac cccggggaaa
    17401 gaagatcgcc atcaactgac ccggggtctg gccactcccc cttttttagc aatccttata
    17461 tagaagccgt agcgaattac atgctgtgca aagagacgag ctcataaggt cggtgcggga
    17521 gctcctgctc cgttctggct tcagcgcttc atcgccattg aagcttagga gcatcgcctt
    17581 cgacatagtc gctcgtcggg accgcaatct catcttggtc aaggttctaa cgaacatcga
    17641 tgccttctcc aaggagaacg ccgaggaact gaaggtactg gccgaggcgc ttggcggatc
    17701 gataatgatg atcggggagc gttccggttc gggcgacctg gagcagggca tcgtctactc
    17761 ccgtttcgat attcccataa tcgccttcgc caccatgaag gaccttcttt tggatgacga
    17821 gccaccgttc atcttcgccg cgccaggagg tctctacgtc cgcctggaca gcgacctgct
    17881 gcacaatctg agggaggacc ggagcgtaag cctcggaacg ctggccgagg tggcgggcgt
    17941 atcccgccgc acgatacaga tgtacgaggc tggcatgggg gccatgatcg acgccgcgct
    18001 tcgcctggag gagttccttg gcaaacagat agtggtgccg gtggacccca tgggctacaa
    18061 gcccccgacc caggagcgcc gccctctgga catggagaaa tgcgacgatt tcagcaagaa
    18121 catctacacc ctgctgatgc agatggggct gctggtgaaa ccgaccgaga agtgtccctt
    18181 cgaggccctg acggtagacc acgatctgct catcctcacc ggactgggca aggacgagac
    18241 caagctggct gacaaggcca aggtcgtgtc ggacatctcg cgcatcaccg gaaaggaatc
    18301 ggttatattc atcgagaggc tacgcaccag gcacagcatc gagggcacgg cgctcatcgg
    18361 acgcgacgag ctgaagaaca ttcatgaatc ggagcgcctg cgcaagatgg tgaacgcccg
    18421 gagcgaggta gatgagagag attgagctga acggttcccg gacctatgtc ctcccggtga
    18481 tcaaaggatt ggtcagcgaa ggggagaagg ttcgcgcggc catcgtcgaa ctgagaccgg
    18541 aagcggtcgg catctccata tccaaggagg agctgcaggg cctgcgctcc tatcaggacg
    18601 aggagataga gctgagcgac caggaggagg cctacaaggc cggattgcta gagttcggcg
    18661 aggtgcagat gcctccgccc tgctaccgcg aggcgctcaa ggtctgcgac gagctcggcg
    18721 ttccgctgat acctctggac atgaacgagg acctgttctc ggaacgctat tgcgagctga
    18781 tcggcggtct ggagctgatg aaggagtcgt tcttttcgca tcgtgtcgcc aggaagcgtt
    18841 tcgacctaga gagcgccgag gcgttcgttc ttgactatga ccgcaaggtg aacggcggga
    18901 gagggctgtc cgcattgaac ttggaacggg aggcgcatat ggccagcacc gccgcggaga
    18961 tggccttggg acggcgcacc ctgctcctgc tgctggagct ggagcgatcg gacggtgtgc
    19021 tccggcgcat ggaagctgac gcgagggatt aatagccggg agggcgcttg acgaccatgg
    19081 agggggacgg tcggtcgatc gggcgcttcg agaggaaggt cgattccctt ctggccttcc
    19141 tggagaagga ccgcctcaac ctctggcaga ccttcgctta cgtactgatc atcgccctgg
    19201 ccagggacct gtccgaatat taccttctgg acgaggcctt cgtcagcacc gcgcatcctt
    19261 ggatattcag catcgcccat catgtggcct tcttcgccct gacctacctg gggctggtgc
    19321 tcatcctgaa ggtgttctcc ggctcgggcc tccggaaatg cctgaactac accaactggt
    19381 actactggat aattctgctt cccccgttcg tggaccgctt cctcttcggg caggagacca
    19441 actacgccta cttctcctgg accgatttcc tggccgcctt cttcctcatg gagggggatt
    19501 ccttccatcc cggacaggcc gtggaggtgc tggtggtcct cttcgccctc ttcgcctacg
    19561 tgatctggtt gtaccgcgac gaggtccagg acctgccggg gagggcgatg ctggccttgc
    19621 gcctggggct catggccctc ttcacggtcg cggcgatgtt caccttgggc acccccggcg
    19681 cgtacatgcc cgtgggctcg gagggcggcg ttccggtgtt tccgaacttc gacagcacca
    19741 ggtacgtgca gcaccacctc ttcatattcg cctattacta cctggcggga acggtgctgg
    19801 tgctggcgct cagcttcatc gccctacgcg accgcttccg gagggagctt gccgccctac
    19861 gcccctatca gaccgccttc ttcgccctta tcgttctcgc cgggacggcc atggcctggc
    19921 aggactgggg agaggttcgt ttggtgacct cgatactaga acggccgtac tgggtgaacc
    19981 tcgcctatgt gataccgacg gtgctctcgg cgatcctggc ctggcaggcg agcgtcatct
    20041 ggaacgacct gagcgatcgg gaacacgatt ccccgttcaa gaaaggaagg gtggtggcct
    20101 ccggcctact accggccaag gagttcaggg aagcctccct catcctggcc ttcgtggccc
    20161 tggccgtctc cctgctgctg agcgtgcaac agttcctgct aatggccggc atactggtcc
    20221 tggcgttcgt ctattcgttc ccgcccgttc gcttcaagaa cgctctgcta agtccgttgc
    20281 tgatgggggc ggggaccttc ctggccttcc tctacggggc gtccacgccc ttcagcgagg
    20341 tgcgctatgt gatcaacacg ccgtacctca ccggcgcggt cgtgtatcca gcgctctata
    20401 caggagcgtt catcgtcggg gcgttcatgt ttatcgggct ggtcatcggt tcgataataa
    20461 cggatgctga tggctacgag gaggaccggg cgggcggcgt gcgaactata tacaccacct
    20521 atggactgga gaagggggcg gacatggtat ccgtcctaat attcctggcc gccctcaccc
    20581 cgttggccct tttcagctcc tggacggacg tcatcgcctt ccccctgctg gggctggccg
    20641 cctcccttcg attccggaag aagcgctcct cccgggcggt catgcccata gccatggtcg
    20701 ggcttctcta cgccgccctg cggttcctgg gagctttcta gaccagagaa cggaacagca
    20761 ggcggtggaa gcgcggtatg gtcatcatga gcaatcgctg ccaggtctcc tcgcccagcg
    20821 ccatcttggt ccaggcctcg acgtacggac cttcctgacg aacggtctcg aagaaggctc
    20881 gagtgtcgac cacccccaga agccagtgca gcaccggcga tatcaccgtg gcggcccgga
    20941 tatccctcac cacggtgtcc ttgaccaggc gatcgtatct gctgatggcg ttccgatcgt
    21001 cgcccttgac cagagatatc gcggcgtcgc ttgccaatat cgcactggcc agtccgtggg
    21061 agagcccctc gccgctcatc ggggagacca gcccggcgct gtccccggcc agcatgaacc
    21121 gggacgagga aaagcgctcc cggggcagga tgggtatcgg atgggcggaa ggtttgctac
    21181 gatcaacagc cttggctaga ctgtcgtccc agaccgtgct cattccgctc aggagcagtt
    21241 ctttggtgta tccatgaccg cccaccccga agttggcccg gccgcgatag gggaacatcc
    21301 agcccatcaa cgggaacatc ggataccggc gtagcccttt ggtgggagtg tcgataagga
    21361 agacctcgat gtcgtcgccc ggatcgttca tggtcgtgtc gaccgacctg aggcccatgg
    21421 ccatggagtt cgtcgggggc ggaccgaaaa gcgctcgggc gttcctgctg cccgcgccct
    21481 cggcgatcac ggcgcatctg gcggatatct taccgtccgc cgtgctgagc tccacttcgt
    21541 ccgatccgga tatccgttct acggcctttc ctaggcgcac ctctaccccg gccttctccg
    21601 ccatgcgaag aagatgcagg tcgaagttgg cgcggtccac ggtgtaggtg aggcaccgat
    21661 cgaagcggaa gcgctctcgg aagtcccggc cgaccacgtg gaaccccttg acctccttct
    21721 cgatcaccga gtccggaatg gggaagtcca gccgggaagc ggctctcatt agcaccccgc
    21781 cggcgcaggt cttgatccag ggcggcagct gacgctctat tagtaccgtt gaaaggcccg
    21841 cctgggcgca gcggtaggcg cagtaggacc ctacgggccc cccgccggag atggccacat
    21901 cgtacaaggc cagtccgcct tcacctgcgc ttgcggtcct tcctgtttat ccatccctcc
    21961 gcggccacca gccccagcac gccgagcagc gggtacagga tggtgaggtc cacgttaccg
    22021 gccttgacgt tgatggccga ttcacccgag gccaaggcgt tcagcacctg ctcgccccat
    22081 tgatggaccg ttggatcatt gcggtacagc catatggacg gcgccgttcc tccgcttctt
    22141 ccgggggcga agcctatcac cagcgcgatg tccgtatagc catctccgtt gaagtcccca
    22201 agagccaggg tctgaacgtt gtatatgggg ttgttgccgc ccacggccgc tgagaggctg
    22261 gaggtggtta ttgacagcgc aggggagaag gagttgcctc ctacaccata agagtacatt
    22321 aagctgcgat cggtcgctcc actgcccagg taggacgtgc cgacgataat gtccgggtag
    22381 ttgtcgggca tgtcagtggc cgaggtcacg tcccccaccg cgagagctgt gatgaactcg
    22441 ttgttgttct gcattttgaa tagtatagac aatttagcag gccaattcac ggtcggcgag
    22501 atgtggcgaa tgcccacgat gtctagcact agggagtcgt tgaacacgtc ggtcagggag
    22561 cggtccgctg cggacacctt gatgtaatag acagcgttgg tggtgtgcgg aagctgcagc
    22621 tgcttaagcg tctcggtggt ctcggtgaaa ttgaacgcat cgtaccagat gttgcgatcg
    22681 gtcgaatact ggacattgaa tttctcccca gtggtatagg cggatatgcc catctgatgg
    22741 gtcacttggg tagccaagtt aggaacttcg tacacccatt ccatccatct gctctcggcg
    22801 tacttcagct ccaaccgggc ataatcgaac tggaccgtgc cgctcgttcc gttgtgcacg
    22861 aacatcaccc tcagggactg aagctcgctc caggtgtcta ttccggcggc cttgagatcg
    22921 aacgtctggt tcacatctag ggatgagctg gtcggcaaca tgttcgtgtt gaagaaggtg
    22981 gtgccattca acgagtattt gatgtaattg ttgccattgt aaccggccgt ggccgaatat
    23041 tgcaccctca gtattacctg ggtgatcggt tttgtggagt atgtactgtc catggcgaag
    23101 ctgcgaacgt gcatggtcgt tccagaatcg acgttgtagg tcaccccatc atcgtacttc
    23161 aggttgttga tgtcctggcc agtgttgtcg gggttgggag aggaggcctg cttctggtct
    23221 gccaatccga acagcatcga ggtgttcttg taggtctcag tcaaagtctc atagacgttg
    23281 tcgttaaaca ccagattggc catggtcccg gtccgcttgg cgctggtctc gttctccagt
    23341 gagtattcgg ccgaaggcgt cttcagtgtg tcggaaggag tggatggcat ggtcttgatg
    23401 accgtgacct tgacctttgt atcagaatcg ggcgctgcag tgctagtcct gattatatct
    23461 ggatatccgt tgaggtccac atccgagatg gcgacggacg gggtcctctg ggtatggtcc
    23521 caggggttgg tactttctac ggtcggtatg ttggcagcag ggataacggc ccctgggccg
    23581 aaagaacccg ccttggggtt tgtcgttatc ccgatcacct gtcgccattg gttgatccag
    23641 atcttggtga ccccggtctc gtataccgcc acgatgtcgt ccaccccgtc ctggttcagg
    23701 tcatcaacgg caatgtccat ggcaccaggg ttgtcattct ggttggtgta ggtgtttgtt
    23761 cctgatagtt gtgtcttcgt ccaactacca tcgttccaga atacgtatat cccacgattg
    23821 aagaacatac caaatgagtt agcatagctg gcatcaccag aaccggtggc tgaggtatag
    23881 acgaccgcat gaaggaaaga agcgacaatg tcagtatctc catctccatc aaaatcgcct
    23941 gaccccaggg caccaaccac ctcatttatc gcggaatagg acgaagcggc gaagcgatcg
    24001 ttgctgtagg atgtcgccca gacagaggag tcctcgttag ccaatccttt atcattgttt
    24061 tcagcagctt gtgttccggg ataggcatcg aacgcggtac atatgatgta gggtagcgtc
    24121 gaccaggcgc tgcctgcaaa gttctggttc ctgtaccagg cgagggatac ggtgctgtcc
    24181 tgataaccta ccacgacgtc ctgataccca tcattgtcga tgtcggccag gaccatgccg
    24241 gtcgggccat tgtaggtgtc ctggtctata taggtagcgt cccactggtc gaaccgctcg
    24301 ccgttcttgt accagaccag tttattgtcc tcccaggtgg ccccggaagc gctccaggtg
    24361 aaggagcccg cgcctacgct ggccaccatg tcagtggtgg agcgcggggc ggtcacgttg
    24421 aactggtagt tgaggttgta gtaggtctca ccggtaccgt agttcccgga gtcggtcagc
    24481 accggtatga gcatggagta tgagttcctg cccgccagcc accaatcgtt gttgggttct
    24541 agcagtttga tctgcacggt gtagaccgcg tcgatgacaa cgctgtcata tatccggctc
    24601 ggactggtcc cggtcttgga cgtcttgtat atctgagaca gcggagcgtt tttagtgagg
    24661 gttggtgcgg ccccggacat ccaggtagtc ggcgtgggca gggtctgctt gataacgtac
    24721 tttccagtat aatcgtttac ctggatatca ttaatgacca ccctggttat gttggagtcg
    24781 acatccttgg tgaatatctt cagatacatg atgtcggtgt ggttgaacga tttgcatagc
    24841 tcaagctggt tcgccgaatt aaccttgtag gtcttaatta ttggatattg cgccccggta
    24901 accgagatgc tgtctggtat gttcaccacg gtcccggtgt tgtccctcag agatatttgt
    24961 agcgggaaat acaggggctg catgggggcg ctgaggttga tgtagtacct gtggaaggtg
    25021 gcgtatatgc caccgtagga gaaggcgttg ataagtttgc tgggcggcgc caggagagcc
    25081 ccggtggtgg ggttgtagag ggagaaggag ttctcgatgg ccagattgac cagcttgtcg
    25141 ctgtaaatct ctatgtaaaa cttttcgccc ggagtgaagg agcgggagat attgttatcg
    25201 gacgccctcc tgatgtaata gaaggtggtc cctaccgggc cgccgctctg ccctccgctg
    25261 gcgtccggcg gatatgtgcc gttcaccagg tagctctcgt aatcgtagaa cggtcctatc
    25321 tgagtgttgt tggtctgcga accgccgcca ccggcgtact gagcgacgag ggtgaagcgg
    25381 gaggaggcgg acttgtcggt catgtccttg gccatgacca tgaccaactt gtcatcgtag
    25441 gcgatcttac cgacgatggg gtcgctggtg aagacgccgt cgttgtccgg gtcggtcagt
    25501 tgaacgaagt taagaccgat cgaccgggcg tcgaccatga cgctggaggt gttcagatta
    25561 ccatcggggt ccatcaccgc ggcggagaac cggaagcttg aaccgtcaat gatgatgctc
    25621 ggcttggtcc cgcgggaagt gatgatcggc gcgtacgaac cggtaacctg cccgccaatc
    25681 atctccgcct cccatacctt ggagttatgg acggtgtcga tgatcaccac gctgagcggg
    25741 gtgtccgtgt tgatcccttc gatcttatac ttccatacct cgccgggcgt ccaggtcgtt
    25801 ccgagcggat tactggacga gttcatcttg agggatatta ggttggtgcc gtatgtgaac
    25861 aggtagatgt tggtgctctg gttgtccaaa ggctggccgc ccttgtgcgt gagggagatc
    25921 cagcgggcgc cgtccaccac ctccgacaat tcgtaatcga tctccgcata ggtctgttct
    25981 tctggcgacg gtatggtggc cacgtagaac attatgctgg agaacagggt gaccgtgatg
    26041 gccaggatga gcaggttgcc aatgatgtca gatactgccc tgcgacattt cctgagctgt
    26101 ttctggaatc ggaccattct tcatccctcg ctaaagctac cgctctagaa tataatctat
    26161 ggaacaagtg gatatttaat gtttgcctgg actataaaag tggtatcaga attcgatgcc
    26221 cttcctggcc accagcccct cgtcgtacgg gtgcttctct acggtcataa ccgtgaccag
    26281 atcggcctcc tgcttcagtt cgtccggcgc gttccttccg gtgcagacga cctccacccc
    26341 gccctctctg tccctaagag cgccgatgac ctcttccaga gatattaacc cgaagtacag
    26401 ggccacgttc acctcgtcca aaaccagaag gtcgtactcg cccgagccta gcatggagcg
    26461 ggaaaggtcc agagcgcgct ttgcgcaatc cacatcgtcc tggcagtgcc gccccttggt
    26521 gatcagcttc ccggaaccga actggaaaac ctcgacgccc attcttcgta acgcgaggat
    26581 ctcgccgtag tcctcgccct tcttcatgaa ctgcacgacg cccacccgca ggccgtgccc
    26641 ccaggcgcgc agcgccagac ctagagcggc ggtggtcttg cccttcccat cgccggtata
    26701 gacctgcagc agtcccagtc cgttcttctc catcttatcc gtacatcatt aggttccagg
    26761 cctttaaata ttccaatccc cggtaatcta ggcatgatgg agctggagat caaggtaccc
    26821 tgcgaggacc tgatcggtct ggaatcgcgc ctgaaaggaa tgggggcgtc gcacgtggag
    26881 gacctggacc agatcgacct gtacttctcc cacccggctc gggatttcgg cgtcaccgac
    26941 gaggcgttgc ggctaaggag ggagaacgag cgcacggtca tcacctacaa gggcccgaag
    27001 ctcgaccagg acaccaagct ccgagaggag atcgagctgg gagtggagga cctcgaccgc
    27061 atgtccttgg tcctggaaag gatggggttc cggccggtga tccgaatcgt aaagaagcgc
    27121 accgtctacg acctccaggg cattcatttc tgcctggacc gcctgccgga gctgggtaac
    27181 ttcgtggaga tggagtggca gggcgatgac ctggacttcg gaaagaaaag gatcatggag
    27241 ctcaagcaaa agctcgggct gagaggaaat gagcgacgct cctatctgga gctgctcatt
    27301 gaaaaacgtt agatgatcac agggtgcgga tcttctcgat cacgaagtcc ttgatcttgg
    27361 ggtcgtccgg tatcgtgacc gacttcttga accgctcggt gccgtctggc aggtaataac
    27421 cacgggacag ggagatgaac tcgttctcgc cctcctgggt gatggccttc ttccgcgcta
    27481 cctctatgaa gttgttgcgg ccgaagggta tcttctcggc gctaagcgtt acaaaatcca
    27541 cgttctttcc cggcgcatcg tcatccattg cggttgcctc catttcggta gctatgcaac
    27601 gttcggtaaa attataaagg tttgccttat gtatatacga tgctggcaca tttatcttga
    27661 tggacgaatt gatgatattg atgacgcttt caagcaccaa catcgacagt taaaaataga
    27721 acggcctaga tgaaagggag catggatgga gagggtccga agcgcacttg cccgcgatgc
    27781 ggagcccagg tgccggagga cgccgccttc tgccagcggt gcgggctccc ccagaacggg
    27841 acggacgacg tggcgcgaca atacgctttt tacgctcccc cgccccggcc ggtgagggag
    27901 aagagcagtt tgcagtccgc cagggaggtc atcaggggca tcggggcgta catgacgctc
    27961 gtcgttctgg cgttggtaac gatcaacgtg ggcatcatgc tctggggcat gcaatacgtc
    28021 atccccgagg cctgggactc ctacacctcg ttgttcgtcg ccctgccctg gctcgtgagg
    28081 ttcctggagc tgccgggggt gtggttcgtc gtctactaca tcctgctggt gatcgcggtt
    28141 ctcttgtcgt acgccatcat gctgtatctg ggaagaaagc agctctggaa tgagctccga
    28201 ttcaaaccga gcgcgcattc gccgctgtac ggcataacca ccatcttcct ggcggtactg
    28261 gcgatgaacg ccgcctacta cctgctgctc ggtttgttcg gcatcgatcc ctcctccgga
    28321 ggcgacaccg gtgagctgtg gcagaagctg tacagcctgc tccgggcctc ggtctgggag
    28381 gaggtcattt gccggatcct ttacatcggc ctgcccctcg gggccgtgta catcctgaag
    28441 ggcaagggag cgccttacca caggtacgtc ctgggaggga actttcagtt cggtccctgg
    28501 gagaagttct tcctggtgtt ctcctcggcc atgttcgccc tggcgcacgt cttcagctgg
    28561 gacctgtaca aggtgccgcc gaccttcctg gccggactgg ccctcggcta cctgttcctg
    28621 aagtacggtg tctacgccag cataatgctg catttcttca tcgattacct cagcttcccc
    28681 atggacgtct ggcctggtga cggtacggac atgatcatgg gcctgcttat gctggccttc
    28741 atggccctgg gggtggtgta cctggcgtac tacttcgtta aggccttgga attgttcagc
    28801 ggccggcaga tcatcaagtg gggcgacccc cgaccggtga gcgtctatta ccagcccctc
    28861 tcccccagtg ccaaatacgt gccctacgac ggtgcgctca caacgccttc ctttggattt
    28921 gtttgcaagc actgcgcagg cacggaggcg cggtatgtgg acggtaagtt cgtctgctcc
    28981 cgttgcggca gggaaagttg atcagtctag agaggacagc atgccgcgca ggcggtccct
    29041 ggataccaat gaccgttcca gctcccgggc ctcgatcacg tagcgcccat gatagggccg
    29101 gaaggcgctc aaccacctcg ggaagtcaat gttcccctcg ccgatgacca tgtgacggtc
    29161 ccgatcgccg aggttgtcgt gcacatgcat gttcatgaag cggtccttga tcgactgaaa
    29221 atcagggatg ttgccgacgg tgttggagtg tccgatgtcg aagcaaacgc ctaggtccgt
    29281 gccttccatg aacaggagaa gctcctcggg ccccttggcc atggccactg gcatctccgg
    29341 catgttctcc agcgctatac gaacgcccag gtccttgccc cgggcgtcta tcgccttcaa
    29401 cgattccttg gtagcctgga tggcggtgtc ccggtccagt gcggtcagtg gtgacaggaa
    29461 cccggggtgc accgtcacca gatcgatgcc catgcggtgg gcgatctcca tagactccag
    29521 cacctcgttc aacgcggccg ccctcatcct gggatttatg gccccgatgt tgatatcgct
    29581 cagcggcgcg tgaacggaat actccaggtc gtaggacggc gacagtctca gaaagtcatc
    29641 gcggatgtcc ctcaggagat gccttccctc ggccacgatc tcccaggcct ggtaatgctc
    29701 ggccaccctt tccagggcgt aagggaagtc ccagcgcgag agatgcgggg aggatacggc
    29761 gatcaaggga tctccccgtc gatggtctgg ggagcgacgt tgtcgatgaa cgcttccagc
    29821 tcggtgcctt tgatgagcac ctcgatgtgc cccagcggcg cgttgccttc cacgaaggag
    29881 atcttgccga cgaaggcggc ctgcttgttc atctggaacc tgatcccttc ttcgctcgtc
    29941 ccgcgcaaca tgaccgccct ggtactgtcc aggatgcggt ggttccttat gatctccttg
    30001 aagcgggaca tgtcgtcggt cttggccctt atagttccct ggccctcttc cagcacggcc
    30061 cccgggaaaa tgttgagaag gctgcttcgc accctctccc cgtcctcggt ggggtaccat
    30121 ctggcactgg ctacgacctc gaccatgggg aatggataat ttaagaaact atttaaaatg
    30181 ggggcggcat gagaaggtcg gatgcgtagc aaggtcgtcg aggccctggc caatgacggt
    30241 tatcttctgg accaggaggc cgaggagttc attttatccc agccatctcc gctgcagttc
    30301 gctcgccagt tcatccccca gatcccgtac cagccgttgg tggttacctt gcgcgatctg
    30361 cgcaccgtgg tgcatgtgga cgcgccccgc ctggaaacga tagtgcgccc ggagccggtc
    30421 tcggtgcgca gaataggcga ggtgcgggtg atgaaagaca tcaccgccca atcggactgc
    30481 ctggggaccg tggaaggctt cgcccgctac ttccaggacc gcttcgccaa tctcaaggca
    30541 ctattgctgc gccgaaggga catgatgggc gccatatccg tccagagggc catggacccc
    30601 aacaagctgc aggccgacga ggtcaaggtc atcgggatgg tcaacgaggt acgggatacc
    30661 cgctccgggg agaagatcat cgagctggag gacgaaactg gacggatgac ggtgatggtg
    30721 cccaaggaca acaaggcggc caaggactcc atcctgcagg acgaggtcat cggcgtg
//
LOCUS       DAOPZI010000017        30582 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1447_length_30582_cov_9.694107, whole genome shotgun sequence.
ACCESSION   DAOPZI010000017 DAOPZI010000000
VERSION     DAOPZI010000017.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 30582)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 30582)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30582
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1447_length_30582_cov_9.694107"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1048
                     /locus_tag="PKM11_04665"
     CDS             <1..1048
                     /locus_tag="PKM11_04665"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX47834.1"
                     /translation="ALGDVVKSFSKSLVQTVIAFVASMLITGLILMLLTDWDLGTSLM
                     VGAILGGTSGAIVIPIISALKVSTKLKMVLTLEAAITDVLVIVVATSLIVFMSQDSPS
                     VMSAVELLVSTFMVSTMIGIISGIVWTKILQRLNRQPFSYMITIAAMLIVFSVTNFLV
                     DKAGGGAIAVLVLGLTIGNWDEISKVLKQKGEQFALGDKVKRFHDEIAFLIRTVFFVY
                     LGLVITTIHFTAWYVLLGLIVFFGLLIARYISLLLADRYIGLDASDEMGLFYMMPRGL
                     AAAVMASIPLSYPLVFNNETATAILGITVVVVLLSTVLASIGAFYMEIHSKRNGRDVQ
                     KENDISSGPDKEGA"
     gene            1051..2043
                     /gene="dph2"
                     /locus_tag="PKM11_04670"
     CDS             1051..2043
                     /gene="dph2"
                     /locus_tag="PKM11_04670"
                     /inference="COORDINATES: protein motif:HMM:TIGR00322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043364 - glycyl-radical enzyme activating
                     activity [Evidence IEA];
                     GO_process: GO:0017183 - peptidyl-diphthamide biosynthetic
                     process from peptidyl-histidine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphthamide biosynthesis enzyme Dph2"
                     /protein_id="HNX47835.1"
                     /translation="MDLQLERAVSEIRSMNAKLVGLQMPEGLKTRARDFAANLEAATG
                     CQVVILGDPCYGACDLRSIKGLDLLVHVGHAPMPDLRPSIPTIFLEVRMDFDPVKSIM
                     GDIEKVKSRVGLVATAQHVHLLTAVQSALKSAGRNVLIGVGDSRVASPGQVLGCNVTS
                     ALSVAKDVEQFIFLGSGYFHPLAVSLGTGLPVLCIDPYRGTVDDVSEAREKVIRQRYA
                     AMAKALDAKDWLVLLCDKPGQRRYELAVRCRDILRRKGMRADLVQLNEVRADALLPYR
                     AEAAVSTACPRLAIDDGPHYPIPLLTPWEMEMVLGLRSMDEYQFDQIMAGETPD"
     gene            2057..2251
                     /locus_tag="PKM11_04675"
     CDS             2057..2251
                     /locus_tag="PKM11_04675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47836.1"
                     /translation="MSRTSRDLGRLQIIVAKPSAYAHVQAEIDQRAKAGRSLGQLKPK
                     HIFRYEDEAKFQERLKGRMA"
     gene            2301..3062
                     /gene="mtxX"
                     /locus_tag="PKM11_04680"
     CDS             2301..3062
                     /gene="mtxX"
                     /locus_tag="PKM11_04680"
                     /inference="COORDINATES: protein motif:HMM:TIGR03270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanogenesis marker protein Mmp4/MtxX"
                     /protein_id="HNX47837.1"
                     /translation="MLAPEHIFQKAVANHATVGIGLGEDSRKVLRSVRNAEKNGYARM
                     ITFDSAKEMVSALRRGEVDAVVRGDLSANEAMAEVKSQFSHDHLLRAALMQPKGGRMF
                     FLAPVGVDEGWGVAQKLEFIRYSAPLFLQLGIAMEVGVLSGGRLGDIGRSAEVDRTIR
                     EAIEVERLGKGEGFDVEHCQILIEDAVRRKNLVIAPDGISGNVIFRTMHLVDGCVSMG
                     APILNLEQVFIDTSRAKKCYADSIALASALAHQGK"
     gene            3100..3582
                     /locus_tag="PKM11_04685"
     CDS             3100..3582
                     /locus_tag="PKM11_04685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl tetrahydropterin synthase family
                     protein"
                     /protein_id="HNX47838.1"
                     /translation="MRLEIDGEFAGIRFSACHFIAGHDKCGRLHGHTYVVSLKLHGSM
                     GKDGMVMDFIPLKKELRAIAEELDHRVLVPANSKKITLTMGEEVMIKTCGKKYSLPRE
                     DVVLLPTAESSAEELCQFILTKVLENVNFPSNVKEVEVGVHEELGQSAWVSKRLGVRK
                     "
     gene            3579..4247
                     /gene="queC"
                     /locus_tag="PKM11_04690"
     CDS             3579..4247
                     /gene="queC"
                     /locus_tag="PKM11_04690"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HNX47839.1"
                     /translation="MKAICLLSGGLDSTVTLAYAIHQGFEVTALTINYGQRHKRELDA
                     ARAVAAHYKVPHIVMEFPLTGFRSALTDVNIPVPDRRSEEIGYDIPDTYVPARNIVFL
                     SLAAGMAESVDASAVFIGANAIDYSGYPDCRPEFFQAFENMLEVGTKRGVLGHPVSIE
                     HPILKKTKAEIVKMGMKLEAPLHLTWSCYRGGEKACGHCDSCVLRLKGFKEAGTKDPV
                     AYEG"
     gene            4250..4879
                     /locus_tag="PKM11_04695"
     CDS             4250..4879
                     /locus_tag="PKM11_04695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX47840.1"
                     /translation="MLVNEMFLSIQGEGRTMGLPTVFVRLSGCNLDCRWCDTRYAEEG
                     GSEMSVEEVLEGVNGYRTRHVCLTGGEPLWHDGVPELISRLLEEGKQVSLETNGSLSI
                     AGLPDHPGLMISMDHKCPSSGMEGRMLLENLRLLRPKDQLKFVVADQEDLEMAEDVLR
                     KFEPDCPAIFTPVGGLTLGPVVEFVLKHKLEVRVLPQLHKLIWGERRGV"
     gene            5038..6642
                     /locus_tag="PKM11_04700"
     CDS             5038..6642
                     /locus_tag="PKM11_04700"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - leucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HNX47841.1"
                     /translation="MTELRTSYSQDHSARDGLEADRIFTSHFNRLALDPLTPDHVEIL
                     DTTLRDGEQTPGVALSMDDKIRIAQLLDDLGVDVIEAGFPRTSPGEQEAIRKISSLKL
                     RAKVCGLARCSREDIDSAVDNGVDYVHTFIATSEGHMKNKLKMSREQVKARAVDAVEY
                     ARSRGVIVEFSCEDGTRTELDFLKEMHIAVQEAGVHKINLPDTVGTMSPPAMEYLVSE
                     VMKVTKVPLSIHCHDDFGLAVANSLAAVRKGARQVHVCVNGLGERAGNAALEEVVMGL
                     LAFMNVRTNVETRKLGMTSRAVARMTGVPIPDTKAIVGNNAFAHESGIHVHGVLKDPS
                     TYEAFSPELVGMQRNIVMGKHTGAHSVKEKLSEYGIILPEEMLSTVVSKIKTLAESGK
                     EVDDAELVALALHIQGQVNKEHQHVKLKEFTVFTGMNITPTSTVVIEVDGKLVRSSDV
                     GIGPVDAALNAIRTAVSENISLVEYRLNAITGGSDALCEVTVKLKMNGDQKVMSVGKS
                     IGSDIVLTSVNAAMDAVDRLLGRQKS"
     gene            6652..7920
                     /locus_tag="PKM11_04705"
     CDS             6652..7920
                     /locus_tag="PKM11_04705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HNX47842.1"
                     /translation="MRKDPKTISEKILSLKSRTDAWAGDIVEADVDHVMVNDVTGPLA
                     FQEFEALDCEPVRDKIVLVPDHFVPNKDVASAKQAKEMRDFAKRWGIKNYFEVGRGGV
                     CHQVMLDNGFAYPGALVVGADSHTCTYGGVNAFATGVGSSEAAAVFATGQLWFKVPGS
                     IRVLLKGRPSKYVGGKDLVLKLISDIGVDGATYKTLEFGGTGVSSLTVSDRLSVSNMA
                     IEAGGKAGIFPCDAATVAYMKTVRKDGFNAALPDDGASYERTLEYDLSGLESMVALPH
                     LPSNGKAARDVGVQIDQAYLGSCTNGRIEDLRLAAEIMRGRKVHRDVRMVIVPASVKV
                     FDQAMSEGLLLEFSKAGAFVSGPTCGACLGGHMGILAPGERCVSSTNRNFIGRMGHRD
                     SEVYLAGPAVVAASAITGRITDPRDLEAVQ"
     gene            7917..8411
                     /locus_tag="PKM11_04710"
     CDS             7917..8411
                     /locus_tag="PKM11_04710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HNX47843.1"
                     /translation="MKGVKGKVWRFGDHVDTDQIIPAERLTSDNNDKLGTFAFEKVRP
                     EMVKLVNQGDVIVAGRNFGCGSSREHAPRALLQMGISCVVAESYARIFYRNCINTGLL
                     PVECHVDADDGDVLSVDLSKGIIINQTKGKEWRFAPFPKFVQDLMDKGGLMAKIKEEK
                     RCKK"
     gene            8399..9514
                     /locus_tag="PKM11_04715"
     CDS             8399..9514
                     /locus_tag="PKM11_04715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate family dehydrogenase"
                     /protein_id="HNX47844.1"
                     /translation="MQKIAVLPGDGIGPEVVAEGLKVLNAISENYSVKFDFQEFNINS
                     ERYLSTGKLVTEEDIDQLRKFDSIFLGAIGDDRVKPGVLEKGILLALRFSFDQYINHR
                     PAPLWKPFGRLKRDVDFNIDVFRENTEDYYIGAGGRVTGGKGTIDMRVKRHLYDMKVR
                     LEANADASDDFAFEIGMMSRKNIERFADHVIDFSNLIGENYITVVDKANVCSNIYSLW
                     REVWDEKCRKAGKEHGYMYVDAMTMALVKNPDKFRVIAVPNMFGDIITDLLAEVTGGL
                     GLAPGGNINPKGISMFEPVHGSAPKYKGMDRINPVATILATKMMMDNLGRRDLGEVIF
                     KGVRGAFDKGVYTQDLGGKYTTKQMGDAVVAAIHALK"
     gene            complement(9572..10645)
                     /locus_tag="PKM11_04720"
     CDS             complement(9572..10645)
                     /locus_tag="PKM11_04720"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024831.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HNX47845.1"
                     /translation="MRIVEVNAFHYPFIGGIENRLHHICRRLGKEHEVFVLTSRLPGT
                     AEREEMDNYTVIRLPSRYLKIYNPPYVRISKVREALDELRPDVVDLHYRWSGSLIKGV
                     LGYEGPKIYTCHNTLGEGVGLTHYASELNDRLFLRHLPEFDRVVCVSDYMKRDVAARG
                     FSEDRLLTIYNGVDIPDRTGQDGDYILSLGRLVRLKGLDYLIKAMQHTNCHLRVCGEG
                     PERKNLERLSQHLGLTDRIDFMGWISEEEKKRMLCECRMFVIPSVHEAYGMVAAEAMS
                     YGKPVIASNTGGLPEVVGDAGILVPPQDEMALAEAINALGQDEGRRAQLGNAAKERMK
                     AFSWDEMAKRTLETYQEVVRKGQ"
     gene            complement(10655..12490)
                     /locus_tag="PKM11_04725"
     CDS             complement(10655..12490)
                     /locus_tag="PKM11_04725"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: protein motif:HMM:NF003068.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HNX47846.1"
                     /translation="MRTLYIHADFMEFEVKKPTPLAEAITDQEKTGRMDEVLVAFITV
                     EKNDQDKAEAVASQASADIMETAKKVGAERIMLYPYAHLSTELSDAETGKKVMREMER
                     LVTEGGWQVHRAPFGWYKAFKISCKGHPLSELSREIEGEETAAAPKGEERFIVLLPDG
                     SEVDPRDYKKGTECFQIMMAKEALKKDWPSTGEVKYTRLCKKFGINWESMSDAGHMCF
                     QPKGALMFDLVADYSSRIVNDITLPVYTVRGTNMFSLDEGPVAEHAKLFGDRLYVIKG
                     EKRDFVMRYAACHQQFAMMRLWNISYKTLPFGAFEVADSYRLEQSGETMLCFRTRRMN
                     MPDLHVVCKDIPESEDWFTRLDERIYKEANNLGRDYEMLVNFSSWEAYQNHKEMLMHI
                     VRKHDKPALLHFYPEGINYYWTVNIEYHILDDLKRAREIGTVQIDVGNAQRFGITYTD
                     ESGKKVFPVILHTAVIGTVERYLYMLFDTAVGMEAQGKLGTLPMWVLPEQVRFMNVSE
                     PHLEKARELADRVRKAQVRVGLDDRSETVGKKVREAKQDWVGYAIVIGDKEMTSDVLT
                     VYDRSQNKNVEMTVDQLIEKVRGEIGDMPFRPMYLPSELSRRVDM"
     gene            12638..13525
                     /locus_tag="PKM11_04730"
     CDS             12638..13525
                     /locus_tag="PKM11_04730"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HNX47847.1"
                     /translation="MRSFRLSRDVTGAVNVLLIVLIAVLMVSASTVVILIYQGGQSEE
                     GSSDIVAVGQTIKVNYTGKLLDGRVFDTSYLTVANDDANYPKTLSFTKRSNSSYTPLS
                     FQVGAGRMISGFDAAVVGMKVGETKTVTLTPDEAYGDMDPSKLVTFQLTENVPLLKVF
                     TSSAFQAEYGVAPAYHLMVSDPRYGWDAIVEAYDEQADRVNVKNVPTIDSLYHIYGTG
                     SVGWDVKVMAMDSSSGLITIQHQLDDGDSDMIKGLDGTSTFFITGVDQDGGTAMRNYN
                     TELLGKSLVFTITIVSIVD"
     gene            complement(13554..14165)
                     /locus_tag="PKM11_04735"
     CDS             complement(13554..14165)
                     /locus_tag="PKM11_04735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47848.1"
                     /translation="MFSVGEAFYTLFSPLGLAGWLLCTFLLFYIDAIVFPTLPELFVV
                     LFFIAGYGTLPDWALWSMFVLVIALAEVLGITTLYLVVKRLEVPPKISRVIERYRRFL
                     LLQDERMILLNRVAPILPFTGAFVALSGWSYRRSLFYLVLGGTLKYGLILAASNYFLI
                     YMEKGMAADVTLVMVVVIIVLSFIASSYRKRKADKQGGETLSQ"
     gene            complement(14181..15359)
                     /locus_tag="PKM11_04740"
     CDS             complement(14181..15359)
                     /locus_tag="PKM11_04740"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX47849.1"
                     /translation="MKIAMFTDSYLPTRDGVVNSLLLTKRELERMGHTVYILAPDPAD
                     PADREEGVHYFRSIGFQQYSGYRIPIFPTDKCHILAKLDVDVIHVHGLMFQAVRAMLA
                     GRALKKPVVLTFHTMVTEAAKFYNFTPFPEWVIQLGMWSYLRIILHRAEVVIAPTLAI
                     KNEIKRYAPHIKRFEVIPTGVDLDRFNPKLDGSEVRKRYGLEGKKIVLHLGRIAWEKN
                     IELVLRGFSILSEQEPDARLVLVGDGPAKEHLVRLTEELGLADKVTFTGFVSDEELPQ
                     YIAACDVLTLASKFETQGLVVLEAMAVGKPVSGIRYRAVAELIREGENGELFEETPYS
                     WSQATSRLLKDPLKYREGALARAGEYSAGQWATRLLDIYRYAVESKAGRVNNKVFLKH
                     "
     gene            complement(15370..16680)
                     /gene="thiD"
                     /locus_tag="PKM11_04745"
     CDS             complement(15370..16680)
                     /gene="thiD"
                     /locus_tag="PKM11_04745"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR00097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HNX47850.1"
                     /translation="MAIILTVAGSDSVGGAGVEADIKAISSMGAHAAVALTAVTAQNT
                     LRLREIFPLPTEQVTAQITAVAEDTCISAVKTGMLHSARTVRAVASLLTELKVPLVID
                     PVLFAGVGASLHKEGLVESLAKDLFPLATVVTPNREEAETLSGMKITDDRSLEEVGNI
                     LLGLGPQAVLLKGGHLDGNMARDLFFTEEGVMELVSPRLDRKVHGAGCTLSSFIAAGL
                     GLGLEPKEAVQEAKRRIYDSIAMALPVGKGLLAINPMATLYKEAMSGRMVEEVRSAVE
                     TIEQRLPPELVPEVGMNLAYALPYPQGYREICGVQGRLVRVGQHIRRAGEVRFEGSRH
                     IARVVMAATAADPEVRCVMNLRYSEETLAALKSFSLDIGSFDRTEEPESVSSMEWGTA
                     QAIERCGHVPDVIFDRGGVGKEPMIRVLGRDPEEVLGKIEKLMR"
     gene            16782..17150
                     /locus_tag="PKM11_04750"
     CDS             16782..17150
                     /locus_tag="PKM11_04750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47851.1"
                     /translation="MKASSGHLVLNTRTEYQELAEVFPELLKLFLEETDQVPEDPEIM
                     QMFIHLNQMDLEANRKPEGYNRKGRMRLIFPTNRMEFYVKGSSKSGEVVRVAEKISKM
                     LTKNGFEHELEWNTLSCLEL"
     gene            complement(17152..18597)
                     /gene="argH"
                     /locus_tag="PKM11_04755"
     CDS             complement(17152..18597)
                     /gene="argH"
                     /locus_tag="PKM11_04755"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: protein motif:HMM:TIGR00838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HNX47852.1"
                     /translation="MVEKQLWSGRFAEGPSEMTLSFTSSLSVDTRLAWYDIVGSLAHA
                     KMLGKTGIIGKDESEVLSNGLKQLLIDLESGQLDFSAELEDVHTNMEHILIQRVGEAG
                     KRLHAARSRNDQVSTDFRMFVRDAILEIVTLILDAQSELLERAAKETITIMPGFTHLQ
                     HAQPVSLGFHLLAHVFRLQRDAERFLDAYKRLNQCPLGAGALAGTGHPIDRKMTSTLL
                     GFDRPTDNAMDTVSDRDFALEFAYDCAQTMVHLSSMGEELVLWTSPEFRFAEMPDAFA
                     TGSSIMPQKKNPDVAELVRGRSSIAIGNLMQLLTVMKGLPLSYNRDMQEDKGSVFSSY
                     ETLTSCLFMIGPMYRDLSFDRERMAKACADGFLNATDLADHLVQRGMPFRQAHEVVGA
                     AVQHCVKKGKRLDSLTIKELKGFSELLDKTSLEFISLDACLRRRTSAGGTAPERVQEQ
                     LLSAQTILASHRGECESEIIRLDDVWEELRK"
     gene            complement(18603..19820)
                     /locus_tag="PKM11_04760"
     CDS             complement(18603..19820)
                     /locus_tag="PKM11_04760"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HNX47853.1"
                     /translation="MAARAKKVREKVVLAYSGGLDTSVAIRWLQQNYDLDVIAVSINV
                     GQPGDLQEAVDRALKIGAVQAYAIDATEDFVNDYIGPSLKANALYMGTYPLATSIARP
                     LIAKIMVDIAKKEGAKFIAHGCTAKGNDQVRFDVSIAALAPEIKIIAPMREWVMTRED
                     EIEYAHKNDVPIKVKKECPYSTDENIWGRSCECGILEDAMEEPPKDAYEWTVDPMDAP
                     DKPEYVEIHFKKGLPVGLNKSKKMSMTDIIKKLNQLGGKHGYGRIDQIEDRLVGIKSR
                     ETYESPAAMILINAHKDLEKMVLTKDVFSYKRGIEQRFSELAYDGLWFSPLMEALTAF
                     IDKTQEFIDGTVRVKLYKGSATIVGRSSPYSLYDTGLATYAEGDQFDHKSAEGFIYVW
                     GLPLRSVAKAQKK"
     gene            20064..21080
                     /gene="argC"
                     /locus_tag="PKM11_04765"
     CDS             20064..21080
                     /gene="argC"
                     /locus_tag="PKM11_04765"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HNX47854.1"
                     /translation="MIKAAVVGGSGYIGGELARLLSRHPKISLEAITSRQLAGQQVSD
                     THPFLRGYVDLKFSESITGDGFDVVFLATPHGASMKLAPEIVRSGAKVIDLSGDYRLK
                     DPATYKKWYGHEHTDLENLGKAVYGLNELYWDEIAEADFVANPGCYPTCSALGLAPLF
                     ANHLVAGGVIIDAKSGTSGAGVEPTKATHHPNCGASVNPYKVGTHRHTPEIAQTLTRL
                     QGRLAEVVFTPHLIPVVRGMLCTMYLKLNDDLNKQELLGMYTEFFRRKRFVRMTDVPW
                     MQAVIGSNHCEVGLEMVGDRNVVVMSAIDNLVKGGAGQAVQNCNAMFGWSEETGLDFP
                     GLGV"
     gene            21083..22309
                     /gene="argJ"
                     /locus_tag="PKM11_04770"
     CDS             21083..22309
                     /gene="argJ"
                     /locus_tag="PKM11_04770"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ornithine
                     acetyltransferase/N-acetylglutamate synthase"
                     /protein_id="HNX47855.1"
                     /translation="MEVFEGGITSPKGFKAAGVHCGIKKEKLDLAVIYSEVPAKCAIA
                     YTQNKVRAAPIEVMMKKDPKTLQALVINSGNANAITGVQGIYDSKQMVFLTAQTLGIR
                     DTLVGVASTGVISRFLPMDKISAGIPKAVQSLGKGPESDDLAARAIMTTDTVKKEASC
                     RVTLKDGTVATIAGITKGSGMISPAMKVLHATTLTFMVTDAHLGKNFNRRWQDMMDVS
                     FNVISVDGDQSTNDISVFLANGMAGGKPADDDPAFWEGVRYIAQQLAKKIVIDGEGAT
                     KLIEVMVHGAKNPVQARSAARAIIASSLVKTAIFGADPNFGRILAALGNSDAEFNLEK
                     VKLVLRSNGDSVTLFEDGAPTLVAGSDVEAAAKRVLSHKKIVIDLDLNNGYSTGEAWG
                     CDLSYDYVKINAMYTT"
     gene            22314..23168
                     /gene="argB"
                     /locus_tag="PKM11_04775"
     CDS             22314..23168
                     /gene="argB"
                     /locus_tag="PKM11_04775"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: protein motif:HMM:NF012899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HNX47856.1"
                     /translation="MPRISDVGVPRQAGKVVVKFGGSSIGGMEQIDAFAKQIAELRER
                     GLTPIVMHGGGPEITDEMKRCGLPVNKVAGLRITDDATLQIAKSVLSRINDRVVVSLR
                     KAGLKAIGVAGSEADTLVAKKMDPVKLEGPDGTKMVDLGHVGEVVRVDPRLVNALCDK
                     GFVPVVYSICADDSGMLMNVNADTAAAALAAGIAAKDMVLVTDAPGVLRVFEDRGSTI
                     PEIKESDLGPLTSSGILKDGMIPKVEACFMALRGGVGTAHIICGTTPNSIVDQLFSGR
                     NLGTRLTR"
     gene            23178..24353
                     /locus_tag="PKM11_04780"
     CDS             23178..24353
                     /locus_tag="PKM11_04780"
                     /EC_number="2.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine transaminase"
                     /protein_id="HNX47857.1"
                     /translation="MDSKQVAELSSYYLFQNYGREAICFSHGQGEHLWDLEGQRYTDY
                     VAGIAVNCLGHAHPELVRAISEQASRLIHVSNLYQIKEQADLGEAMASIVPSPLGRSM
                     FCNSGAEANEAALKLAVKHTGRGKVVACRNSFHGRTSATLSVTGQEKYQKGFEPLLSK
                     NVDFITFNSIEELKNKVNGNTAAVILEPVQGEGGVLPADREYFRTVRDLCTDSGALMI
                     VDEVQTGMGRTGKWFGFQHFGVVPDIISLAKALGGGVPIGAIVTTPDIAKTFTPGTHG
                     TTFGGNPLACAAANAVIRTMKRDKLVERAADLGERWRSELRNVTSGHPEVADVRGLGL
                     MIGVEMGDLAKEFQRFALSKRLLVNVAGGKVLRLVPPLIISEASINDLNSALREFLK"
     gene            24402..25088
                     /locus_tag="PKM11_04785"
     CDS             24402..25088
                     /locus_tag="PKM11_04785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HNX47858.1"
                     /translation="MKEVPQKESVAERTRAYIDAHPSVKDCMAKDLINYSSLARLIMK
                     DLGIKNEEAVMIACRRYAQKLSVRDHEGDILAILADSRLEVKTKICIVTASNDWTVLQ
                     RLERLFTKLINQKALMQVIQGAQAITIIADEKLRNEVVNDVGETNVLKVREDLVEITV
                     KSPQKIGETSGVFSYLASNLSEQGVNMVETVSCYTDTIFIVHEKDMIQAYSLLSNLLE
                     SAEKATEAAH"
     gene            25131..>25996
                     /locus_tag="PKM11_04790"
     CDS             25131..>25996
                     /locus_tag="PKM11_04790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX47859.1"
                     /translation="MKNDPKGKVPLVRTDIPGPLGRSIVDLDEQYLATVTKSAPLVVD
                     RALDERVWDVDGNLFLDFSSGVAVLNIGHCHPAVVKAVQEQAAKVMHFAGTDYYYDVQ
                     SRLAERLAKIAPGPGEKKVFLSNSGAESIEAAMKLARWSSGRKQFIAFFGAFHGRTLG
                     ALSLNCSKRVQRAKYFPTVPGVTHIPYANCYRCPYHQEYPSCGLWCAKILDEVYLDAL
                     LPPDEVAALFFEPVQGEGGYIVPPKEFLTEISRICRSHGILTVDDEVQSGMGRTGRMW
                     AAEHFGLEPDVT"
     assembly_gap    25997..26096
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <26097..26324
                     /locus_tag="PKM11_04795"
     CDS             <26097..26324
                     /locus_tag="PKM11_04795"
                     /inference="COORDINATES: protein motif:HMM:NF012428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX47860.1"
                     /translation="MMRALEFVEDRSTKVPAVKLRDDVVHALLKKGVIALGCGKSSIR
                     LIPPLTISEENLDTGMRLLEESIGAVVRDRK"
     gene            26321..26677
                     /locus_tag="PKM11_04800"
     CDS             26321..26677
                     /locus_tag="PKM11_04800"
                     /inference="COORDINATES: protein motif:HMM:NF019498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HNX47861.1"
                     /translation="MKHLPRTKYEEVSGDGYLKRIVLEAKDIGLKDTLLQEVQFTAGE
                     KVAFHFHQVTREIFYCLVGPAPFVINGQSVVMNEGDCVICEPGDVHGNPVIGNDFRIL
                     VLKVGLKEHDTVWLDG"
     gene            complement(26712..26787)
                     /locus_tag="PKM11_04805"
     tRNA            complement(26712..26787)
                     /locus_tag="PKM11_04805"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(26752..26754),aa:Thr,seq:tgt)
     gene            26908..27510
                     /locus_tag="PKM11_04810"
     CDS             26908..27510
                     /locus_tag="PKM11_04810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HNX47862.1"
                     /translation="MDANLEDKPEKRVLMDLTANPAPLGLLGFGMTTVMLNLHNADLI
                     PLSGVILALGIFYGGLGQVLVGLMEWKKGNTFGMVAFTSYGLFWLTLVGIWTLPTLGL
                     GEPTDKVTMGYFLTIWGIYTMFFFLGTMKSNRATQFVFGSLTVLFFGLALGDFTLIKE
                     ITIASGYIGLVCGASAIYTGLATVVNGANGKVMLPLGVRK"
     gene            27579..28739
                     /locus_tag="PKM11_04815"
     CDS             27579..28739
                     /locus_tag="PKM11_04815"
                     /inference="COORDINATES: protein motif:HMM:NF017181.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HNX47863.1"
                     /translation="MNDGLADIGVQVTFMDKDSLKFLQELCDVPGPSGFEAAATRLMK
                     NYAEGYCDRVFTDKLGNTMFEKVGQKDGPIVLLAGHVDECGFIITGVNSQGYLAFSQL
                     GGWFDQVLLGQRVLVHTRKGVLNGVIACKPPHLMEPEEAKKVVTKDKMFIDVGACNKD
                     EAQAMGVRLGDAVTPDSKMFSVEKQAYKDGKPAGKRTIMFGRAFDNRLGAFAAVELLK
                     ALKKGKVRHPNQIVSAATVQEEVGLRGARTVAASTNPDVAIVLDVDIAGDVPGIDPLQ
                     APARMGEGVSITVYDGTMIPNQPLKELVISICEKRKIPHQLAYVIRGGTDGGLIHTSL
                     TGVPTIVIGVPTRHIHSHVGLFDTADMEACMKLIVELVKVLDRKTVDSLTAI"
     gene            complement(28745..29485)
                     /locus_tag="PKM11_04820"
     CDS             complement(28745..29485)
                     /locus_tag="PKM11_04820"
                     /inference="COORDINATES: protein motif:HMM:NF025637.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HNX47864.1"
                     /translation="MASVRGAHCVWNLMKLCDHRLVRNRPSSCYLMHLHNGSRDRYRE
                     HRTLFRDDRLSGLDLSIHLHCDDEMTDICPFREWAPKLKCEPDRNFWTECEACGRKHR
                     EEQAHQTCLSWHNFLALYRSKETKAWRPEGTTEEYLSIGPGSELHDKVRNWLWRRIRR
                     YVKRRDGGRCTECGIEVKGRRVPYEIHHIVPRSRGGTEHPANLRTLCSVCHRKYTKEL
                     LEDNTDRRRRARERPGREIGEDRPAKDR"
     gene            29680..30441
                     /locus_tag="PKM11_04825"
     CDS             29680..30441
                     /locus_tag="PKM11_04825"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012478.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HNX47865.1"
                     /translation="MTTKSSIVKVSKGDIVHVEYNAYLAESGMLFDTTNADKAKEAEI
                     FNENLTYKPLPLLVGGGRVFPGLDEALAEAKVGELTVVEIPAEKAAGARDPKLVENIA
                     LREFFRQEIRPEIGMEVNMKNRVGTVVAVTNRMVRVDFNRRFAGAALRYEFTVLDKVE
                     GDEAKVMSICEMDYSTAEGFRAIVTEGKVVLYLPDVCKYDQKWLLTKYKVVADLRDAF
                     GAVTVELVEEYLKKEDKPVEVAPAELAEEKSPEEL"
     gene            30496..30570
                     /locus_tag="PKM11_04830"
     tRNA            30496..30570
                     /locus_tag="PKM11_04830"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30531..30533,aa:Arg,seq:cct)
BASE COUNT         6330 a         8859 c         9203 g         6090 t
ORIGIN      
        1 agctctcggt gacgtggtaa aatctttcag caaatcactg gtccagacgg tgatcgcctt
       61 cgtggcctcc atgctcatca ccgggttaat attgatgctc ctaaccgact gggacctggg
      121 cacgtcgctc atggtggggg cgatactggg cgggacgagc ggcgccatag tcattccgat
      181 aatatccgct ctcaaggtat ccacgaagct caagatggtc ctgaccctgg aggcggccat
      241 aaccgacgtc ctggtgatcg tggtggccac atctttgata gtgttcatga gccaggattc
      301 gccgagcgtc atgagcgcgg tggagcttct ggtcagcacc ttcatggtat cgaccatgat
      361 cggaatcatc tctggaatag tctggaccaa gatcctacaa cggctcaaca ggcagccgtt
      421 ctcctacatg atcaccatcg ccgccatgct gatagtgttc tccgtgacca acttcctggt
      481 ggacaaggcc ggcggcggag ccatcgccgt gctggtgtta ggtctcacca tcggcaactg
      541 ggacgagata tccaaggtgc tcaagcagaa gggggagcag ttcgccctgg gagacaaggt
      601 caagcgcttc cacgacgaga tagctttcct catacgcacg gtcttcttcg tctacctggg
      661 tctggtcata accaccatcc atttcaccgc ctggtacgtt ctcctcggtc tgatcgtgtt
      721 cttcggtctg ctgatcgccc gctacatatc cctcttgctg gccgacaggt acattgggct
      781 ggatgccagc gatgagatgg ggctgttcta catgatgccc cgaggtctgg cggcggcggt
      841 catggcctcc attccgctat cttatcctct ggtgttcaac aacgagacgg ccaccgcgat
      901 cctcggcata acggtcgtgg tcgtcctgct ctctacggtg ttggcatcca taggcgcttt
      961 ctacatggag atacactcca agcgcaatgg gcgtgatgtt cagaaggaga acgatataag
     1021 ttcgggacct gataaggaag gggcgtgacc atggacctgc aattagaaag ggcggtatcc
     1081 gagatacgct ccatgaacgc caagttggtc ggcctgcaga tgcctgaagg tctgaagacc
     1141 agggcccggg acttcgccgc gaacttggag gcggccactg gctgtcaggt ggtcatcctg
     1201 ggagacccat gctacggggc ctgcgacctg aggtccatca aaggattgga cctgctagtg
     1261 catgtcggcc acgctccgat gcccgacctc cggcctagca tccccaccat cttccttgag
     1321 gtgcgcatgg acttcgatcc ggtgaagtcg atcatgggag acatcgaaaa ggtaaagtcg
     1381 agggtgggac tggtggccac cgcccagcat gttcatcttc taacggcggt gcagagcgcc
     1441 ctgaaatctg cgggacgaaa cgtcctcatc ggcgtaggag attcccgcgt cgcctccccc
     1501 ggccaggtgc tgggatgcaa cgtcacctcc gcgctcagcg tggccaagga cgtggagcag
     1561 ttcatattcc tcggtagcgg atacttccac ccactggcgg tctctctggg gactggcctt
     1621 ccggtcctgt gcatcgaccc ctaccgggga acggtggacg atgtctccga agccagggag
     1681 aaggtgatca ggcagaggta cgccgccatg gccaaggccc tggatgccaa ggattggttg
     1741 gttctccttt gcgacaagcc cggtcagagg aggtacgagc tggcggtacg ctgccgggac
     1801 atccttcgga ggaaggggat gagagcggac ctggtccagc tcaacgaggt ccgggcggac
     1861 gcgttgctgc cttaccgggc ggaagcggcg gtgagcacag cctgccctcg tttggcgata
     1921 gacgacggtc cgcattatcc catcccgcta ctgaccccct gggagatgga gatggtgctc
     1981 ggcctacgaa gcatggacga gtaccagttc gatcagataa tggccgggga aacccccgac
     2041 taaatttttt ttaattttgt cgaggacgag ccgggacctg ggccgcctcc agataatcgt
     2101 ggccaagcct tcggcgtacg cgcacgttca agcggagata gatcagcggg ccaaggccgg
     2161 acggtcgctg ggccagctca aaccgaagca cattttccgc tacgaggacg aagcgaagtt
     2221 ccaggagcgg ctcaagggca ggatggcctg aacgccgttc cgatgaagat aatatatcgg
     2281 ttggggcgaa tcaccctttc atgctagccc ccgagcacat attccagaag gccgtggcca
     2341 atcatgccac ggtaggtatt ggcctggggg aggattcccg caaggtcctg agaagcgtcc
     2401 gtaacgcaga gaagaacggt tacgcgcgca tgatcacctt cgactccgcc aaagagatgg
     2461 tctccgcgct gcgacgcggg gaagtggacg cggtggtgcg cggggacctt agcgctaacg
     2521 aggccatggc cgaggtcaaa tcccaattct cgcatgacca tctcttgcga gcggcgttga
     2581 tgcagcccaa gggagggcgc atgttctttc tggcgccggt cggtgtcgac gaagggtggg
     2641 gggtggcgca gaagctggag ttcatacgat attccgcgcc acttttcctc cagctgggca
     2701 tcgccatgga ggtcggggtg ctgtccggcg gccggttggg ggacatagga aggtccgccg
     2761 aggtggaccg gacgatccgc gaggccatcg aggtcgagcg gctcggcaag ggggaagggt
     2821 tcgacgtcga gcattgccag atactcatcg aggatgcggt gcgaagaaag aacctggtca
     2881 tcgctccgga cggcatcagc ggcaacgtca tattccggac catgcacctg gtggacggat
     2941 gcgtgtccat gggggctccc atcctgaacc tggaacaggt cttcatcgat acctcgaggg
     3001 ccaagaagtg ctatgccgac tccatcgccc tggcctccgc cctggcccat caaggaaaat
     3061 gattattgcg taccggggcg atagggaagg ggagataaca tgagattgga gatagacggt
     3121 gagttcgcag ggatcaggtt ctcggcctgc catttcatag ctggacatga caagtgcggt
     3181 cgcctgcacg ggcacaccta cgtggtgagc ctgaagctgc acgggagcat ggggaaggac
     3241 ggcatggtca tggacttcat accgttgaag aaggagctgc gggccatcgc cgaggagctg
     3301 gaccaccgcg tgctggtgcc ggccaactcc aagaagatca ccctgaccat gggcgaggag
     3361 gtcatgatca agacctgcgg caagaagtac tccttgcccc gggaggacgt ggtgctgctg
     3421 ccgaccgcag agagcagcgc cgaggaactt tgccaattca ttctcaccaa ggtcctggag
     3481 aacgtcaact tcccatccaa cgtcaaagag gtggaggtcg gggtccacga ggagctgggg
     3541 cagagcgcct gggtcagcaa gaggttgggg gtaaggaaat gaaggccatc tgtctgctgt
     3601 cgggcggcct ggactctact gtaacgttag cctacgccat tcaccaaggg tttgaggtca
     3661 ccgccctcac catcaattac gggcagaggc acaagagaga gctggacgcc gcccgggccg
     3721 tcgccgctca ttacaaggtt ccgcacatcg tgatggagtt tccgctcacc gggttccgca
     3781 gcgccctaac tgacgtaaat attcccgtcc cggaccggag gtcggaggag atcggatacg
     3841 acatcccgga cacctacgtt ccggccagga acatcgtgtt cctaagtctg gcggcgggca
     3901 tggccgaatc ggtcgatgcc agtgcggtgt tcatcggggc caacgccatc gattacagcg
     3961 gctacccgga ctgtcgcccg gagttcttcc aggcgttcga gaatatgctg gaggtcggaa
     4021 ctaagagggg cgtgctcggt cacccggtta gcatcgagca ccccatcctg aagaagacca
     4081 aggcagagat cgtgaagatg ggaatgaagc tggaggctcc gcttcacctc acctggagct
     4141 gctaccgtgg cggcgaaaag gcttgcggcc attgcgattc ctgtgtcctc cggttgaagg
     4201 gcttcaaaga ggccgggacc aaggacccgg tggcctacga gggctgagga tgctcgtcaa
     4261 cgagatgttc ctatccatcc agggagaggg ccggaccatg ggcctgccta cggtcttcgt
     4321 ccgcctgagc ggctgcaatc tggattgccg atggtgcgac acacgttacg ccgaggaggg
     4381 cgggtcggag atgtccgtgg aagaagtgct tgagggagtg aacggatacc gtaccagaca
     4441 cgtatgcttg accggtggcg agcctttgtg gcacgatggg gtgccagagc tcatctcccg
     4501 gctgctggag gaaggcaagc aggtgtcact ggagaccaat ggctcgcttt ccatagctgg
     4561 tctaccagac cacccggggc tgatgatcag catggaccac aagtgccctt cctccggaat
     4621 ggagggccga atgttgttag agaaccttag gctcctgagg cccaaggacc agctcaagtt
     4681 cgtggtggcg gaccaggaag atcttgagat ggccgaggac gtcctgcgca agttcgaacc
     4741 cgattgtccg gccatcttca cgccggtggg cggtctaacg ttgggaccgg tggtggaatt
     4801 cgtcctcaag cacaagctcg aggtaagggt gctaccgcaa ctgcacaagc tcatctgggg
     4861 agaacggcgc ggagtgtgag ccgtgtcata ccttagcaat gattaaataa tatgcttcta
     4921 gtttccctaa tctacatacg aggtatgacg atgagcatca ttatcgtggc agaacactgt
     4981 cttttgcgtg cttaaatcgg ctcatcgctg cgaccttgga tgtaagagtt gggtatcatg
     5041 accgaacttc gaacgtcgta cagtcaggac catagcgccc gtgacgggct tgaggcggac
     5101 agaatattca ccagtcactt caatcgcttg gccttggacc ccctcacccc tgatcacgtg
     5161 gagatactgg acaccaccct gcgtgacggc gagcagacgc ccggcgtggc gctatccatg
     5221 gacgacaaga tacggatagc gcagctgctg gacgacctag gggtagatgt catcgaggcc
     5281 ggtttcccaa gaacttcccc gggggagcag gaggccatac gcaagatcag ctcccttaag
     5341 ctgagggcca aggtgtgcgg tctcgcccgc tgctccagag aggacatcga ttcggccgtt
     5401 gacaatggcg tggattacgt ccacaccttc atcgccacct ccgaggggca catgaagaac
     5461 aagctcaaga tgagccggga gcaggtcaag gcccgagccg ttgacgcggt cgagtacgcc
     5521 cgatcccgag gtgtcatcgt ggaattctcc tgtgaggacg gaacccgcac cgaactcgac
     5581 ttcctgaagg agatgcatat cgccgtccaa gaggccggcg ttcacaagat caacctgccg
     5641 gacaccgtag gcaccatgtc cccaccggcc atggagtatc tggtctccga ggtcatgaag
     5701 gtgaccaagg tcccgctgtc catccattgc catgatgact tcggtctggc cgtggcgaac
     5761 tcgctggcgg cggtccgaaa aggggcccgt caggttcacg tatgcgtgaa cggcctggga
     5821 gaaagggcgg gaaacgccgc gctggaggag gttgtgatgg gcctgctggc cttcatgaac
     5881 gttcgcacca acgtggagac ccggaagtta gggatgacct ctcgggccgt ggcccgtatg
     5941 accggggttc cgatcccgga caccaaggcc atagtcggca acaacgcctt cgcccacgag
     6001 tctgggatac acgtgcacgg ggtgctcaag gacccctcca cctacgaggc tttctccccc
     6061 gagctggtgg gaatgcagcg taacatcgtc atgggcaagc acaccggtgc tcactccgta
     6121 aaggaaaagc tgagcgagta cgggataatc ctgcccgaag agatgctctc caccgtggtc
     6181 agcaagatca agaccctagc cgagagcggc aaggaggtgg acgacgccga actggtggcg
     6241 ctcgcgctgc acatacaggg ccaggtgaac aaggagcacc agcacgtgaa gctaaaggag
     6301 ttcacggtat tcaccggcat gaacatcact cccacctcga cggtggtcat agaggtggac
     6361 ggaaagctgg tacgatcctc ggacgtgggc atcggaccgg tggacgccgc cttgaacgcc
     6421 attcgcacgg cggtaagcga gaacatatcg ctggtcgaat atcgcctcaa cgccatcacc
     6481 ggcgggagcg acgccctgtg cgaggtcacc gtaaagctga agatgaacgg cgaccagaag
     6541 gtgatgtcgg tgggcaagag catcggctcg gacatcgtgc tcaccagcgt gaacgctgcc
     6601 atggacgcgg tcgaccgtct gcttggtagg caaaaatcct aaggtgaaca gatgagaaag
     6661 gatcctaaga caatttcgga gaagatactg tcactgaagt ccaggacgga cgcctgggca
     6721 ggggacatag ttgaagcgga cgtcgatcac gtgatggtga acgatgtgac cggaccgctg
     6781 gccttccagg agttcgaggc attggactgc gaaccggtgc gcgacaagat cgtgctggtg
     6841 ccagaccact tcgtgcccaa caaggacgtg gcctcggcca agcaggccaa ggagatgcgc
     6901 gatttcgcca agcgttgggg catcaagaac tactttgagg taggccgggg cggagtctgt
     6961 catcaggtca tgctggacaa cgggttcgcc taccccgggg cgctggtcgt gggcgccgat
     7021 tcgcacacct gcacctacgg aggggtcaac gccttcgcca ccggcgtcgg tagttccgag
     7081 gcggcggcag tgttcgccac cggccagctg tggttcaagg tgcccggttc tatccgggtc
     7141 ttactgaaag gccggccctc caaatacgtg ggcgggaagg atctggtgct caagctcatc
     7201 agcgacatcg gggtcgatgg cgccacctac aagaccttgg agttcggagg cactggcgtt
     7261 tcgtcattga ccgtctccga ccgtctttcg gtgtccaaca tggccatcga ggccggcgga
     7321 aaggcgggaa tattcccctg cgacgcggcg accgtggctt acatgaagac cgttcggaag
     7381 gacggtttca acgccgccct tcccgacgac ggcgcttcct acgaacgcac cctggaatac
     7441 gatctttccg ggttggagag catggtggcc ctgccgcatc tgccttccaa cggcaaggcg
     7501 gcgcgtgacg tcggcgtcca gatcgaccag gcttacctcg gctcctgcac caatgggcgc
     7561 atcgaagatc tgcgcctggc cgcggagatc atgcgtgggc ggaaggtgca ccgggacgtg
     7621 cgcatggtga tcgttcccgc ctcggtcaag gtgttcgatc aggccatgtc cgagggtttg
     7681 ctcctggagt tctccaaggc cggggccttc gtttccggac ctacctgcgg agcctgcctg
     7741 ggcggtcaca tgggtatcct cgccccgggc gagaggtgcg tcagcagcac caaccgcaac
     7801 ttcatcggcc gcatggggca ccgggattcc gaggtgtacc ttgccggacc ggccgtggtg
     7861 gccgcttccg ccatcaccgg acgcataacc gacccccggg acctggaggc ggtgcaatga
     7921 agggcgtcaa gggaaaggtg tggcggttcg gtgaccatgt cgacaccgac cagataatcc
     7981 ccgctgaacg gctcactagc gacaacaatg acaaactggg cacgttcgcc ttcgagaagg
     8041 tccgcccgga gatggtcaaa ctggtcaacc agggcgacgt catcgtcgcc ggtcgcaact
     8101 tcggctgcgg atcgagccgg gagcacgctc cccgggcgct gctgcagatg ggcatttcat
     8161 gcgtggtcgc agagagctat gccaggatat tctaccgcaa ctgcataaac accgggcttc
     8221 ttccagtgga gtgccatgtt gacgctgacg acggcgacgt gctttccgtc gatctatcga
     8281 aaggtatcat aatcaaccag accaagggga aggagtggag gttcgccccc ttcccgaagt
     8341 tcgtccagga tctcatggac aagggcggcc tgatggccaa gatcaaggag gaaaaaagat
     8401 gcaaaaaata gcggtactgc caggggacgg catcggcccg gaggtcgtgg ccgagggcct
     8461 gaaggttctg aacgccatct ccgagaacta ctcggtgaag ttcgatttcc aggagttcaa
     8521 catcaactcg gagcggtacc tgagcaccgg gaagctggtg acggaagagg acatcgacca
     8581 gcttcgcaag ttcgacagca tcttccttgg cgccatcggg gacgatcggg tgaagcccgg
     8641 cgtcctggag aaaggaatac ttctggccct caggttcagc ttcgaccagt acatcaacca
     8701 ccggccggcg ccgctctgga agcccttcgg acgattgaag agggacgtcg acttcaacat
     8761 cgacgtgttc cgggagaaca ccgaggacta ctacatcggt gcgggaggac gggtgaccgg
     8821 tggcaagggg accatcgaca tgagggtcaa gcgccacctc tacgacatga aggtccgtct
     8881 ggaggcgaac gctgacgcct ccgacgattt cgccttcgag atcggcatga tgtcccgcaa
     8941 gaacatcgag cgtttcgcgg accacgtcat cgatttctcc aacctcatcg gggagaacta
     9001 catcaccgtg gtggacaagg ccaacgtgtg cagtaacatc tactccctgt ggagggaggt
     9061 ctgggacgag aagtgcagga aggccggcaa ggagcacggc tacatgtacg tggacgccat
     9121 gaccatggcc ctggtcaaga acccggacaa gttccgggtg atcgccgtac cgaacatgtt
     9181 cggggacata ataaccgatc tgctggccga ggtgaccggc ggactgggac tggcgccagg
     9241 cggcaacatc aaccccaaag ggatatcgat gttcgaaccg gtgcacggct ccgctcccaa
     9301 gtacaaggga atggaccgca tcaacccggt ggccacgata ctcgccacca agatgatgat
     9361 ggacaacctg ggccgtcggg acctgggcga ggtcatcttc aagggcgttc gtggggcttt
     9421 cgacaagggc gtatacaccc aggacctggg cggaaagtac accacgaagc agatgggcga
     9481 cgcggtggta gccgccatac acgccctgaa gtgaggctgg cggcggttaa accctttcaa
     9541 aaatccttct ctattttgac cctgccctgg atcattgacc ttttcggacc acttcctgat
     9601 acgtctccaa ggtgcgcttg gccatctcgt cccagctgaa ggccttcatc cgctccttgg
     9661 cggcgttgcc aagttgtgcc cgtctacctt cgtcttggcc cagggcgttg atcgcttccg
     9721 ccaacgccat ctcgtcctgc ggggggacca ggatgccggc gtctcccacg acctccggta
     9781 gcccaccggt gttcgaggct atgaccggct tgccgtagga catggcctcg gccgccacca
     9841 tgccgtatgc ttcatgtacc gaggggatga cgaacatgcg gcactcgcag agcatgcgtt
     9901 tcttctcctc ctcgctgatc cagcccatga agtctatgcg gtccgtcagt ccaagatgtt
     9961 gggaaagtct ctccaggttc tttcgttccg ggccttcccc gcagacgcgc agatggcaat
    10021 tggtatgctg catcgccttg atcaggtaat ccagtccctt cagcctgacc aatcttccca
    10081 gggagaggat gtaatcgcca tcctgacccg ttctatcagg aatatccacg ccgttgtaga
    10141 tggtgagaag ccggtcctcg gagaaacctc gggcggccac gtccctcttc atgtagtcgg
    10201 agacgcagac cactcggtcg aactcgggca ggtgccgaag gaacagtcgg tcgttgagct
    10261 cgctggcata atgcgttagc cccacgcctt ctcccagggt gttgtggcag gtgtatatct
    10321 tgggaccttc gtaaccaaga actcccttga tcaacgatcc ggaccagcga tagtgcaggt
    10381 ccaccacgtc cggtctcagt tcgtccaggg cctcccggac ctttgaaatt cggacataag
    10441 ggggattgta tatcttgagg tacctggagg gcaggcggat gacggtgtag ttgtccatct
    10501 cctccctttc cgccgttcca ggaaggcgac tggtgagcac gaacacctca tgctcctttc
    10561 ccagccttcg gcagatatga tgcaggcggt tctctatgcc gccgatgaaa gggtaatgga
    10621 aagcgtttac ctcgactatg cgcaactcac gacctcacat gtcgacgcgc cggctcagct
    10681 cgctgggcag gtacatgggg cggaagggca tgtcgccgat ctctccccgg accttctcta
    10741 taagctggtc cacggtcatc tccacgttct tgttctgcga acgatcgtac acggtgagaa
    10801 catcggaggt catctccttg tcgccgatca cgatggcata gccgacccag tcctgcttgg
    10861 cctcccggac cttcttgccg accgtctcgg agcggtcgtc caggccgacg cggacctggg
    10921 ccttgcggac cctatcggcc agttccctgg ccttctccag gtgaggctcg gaaacgttca
    10981 tgaagcgtac ctgctccggc agcacccaca tgggcagggt ccccagcttt ccctgggcct
    11041 ccatgcccac cgcggtgtcg aagagcatgt acaggtagcg ctccaccgtc ccgatcacag
    11101 cggtgtgcaa tatcaccggg aacaccttct ttcccgattc gtcagtgtag gtgataccga
    11161 agcgttgggc gttgcccacg tcgatctgca ccgtccctat ctcccgggca cgcttgaggt
    11221 cgtccaggat gtggtattcg atgttgacgg tccagtagta gtttataccc tctgggtaga
    11281 aatgcaacag ggccggctta tcgtgcttgc gcacgatgtg catgagcatc tccttgtggt
    11341 tctggtacgc ctcccacgaa gagaagttga ccagcatctc gtagtcccgg ccgaggttgt
    11401 tggcctcctt gtatatccgt tcgtcaaggc gggtgaacca gtcctcggat tccgggatgt
    11461 ccttgcacac cacgtgcagg tcgggcatgt tcatgcgtct ggtacggaag cacagcatgg
    11521 tctccccgga ctgctccagg cggtacgagt cggccacttc gaacgccccg aagggcaggg
    11581 tcttgtagct gatgttccag agacgcatca tggcgaactg ctggtggcag gcggcgtacc
    11641 tcatgacgaa gtcgcgcttc tcgcccttga tcacgtagag gcggtcaccg aacagcttgg
    11701 cgtgctcggc caccggaccc tcgtccaggc tgaacatgtt agtgccgcgg acggtgtaaa
    11761 cgggaagagt aatatcgttg acgatgcggg aagagtaatc ggcgaccagg tcgaacatca
    11821 gggcgccctt cggctggaag cacatgtgcc cggcgtcgct catcgattcc cagttgatgc
    11881 cgaacttctt gcacaggcgg gtgtacttga cctcgccggt tgagggccag tccttcttca
    11941 gggcctcctt ggccatcatg atctggaagc actcggtgcc tttcttgtaa tcacggggat
    12001 cgacctcgct gccgtccgga aggaggacta tgaaacgctc ctctcccttg ggtgcggccg
    12061 cggtctcctc gccctcgatc tccctggaca gttccgacaa cggatgtccc ttgcagctta
    12121 tcttgaaggc tttgtaccat ccgaaggggg cgcgatgaac ctgccatcca ccctcggtga
    12181 ccaggcgctc catctccctc ataaccttct tgccggtctc cgcatcggag agctcggtgc
    12241 tcagatgggc gtagggatag agcatgatgc gctcggcgcc gaccttcttg gccgtttcca
    12301 tgatgtccgc cgaggcctgg gaggccaccg cctccgcctt gtcctgatca ttcttctcga
    12361 cggtgatgaa ggccaccagg acctcgtcca tccgaccggt cttctcctgg tcggttatgg
    12421 cctcggccaa cggggtgggc ttcttgacct cgaactccat gaaatcggcg tgtatgtaaa
    12481 gggtcctcat cttatcgcct gatagggtgt ggttggtaat ggtccacgtg tataaataag
    12541 cgattccgga gtatggtcat agccagcatg gtttctccgg tgctcccgca taagcaatgt
    12601 ttaaattcaa gaaaaggttt gcctgattcg catctttatg aggtcattta ggctatccag
    12661 ggatgtcacg ggtgccgtga acgtcctgct catcgttctg atcgcggtcc ttatggtgag
    12721 cgccagcacg gtcgtgatat tgatctacca gggtggacag tccgaggaag gctcttccga
    12781 catcgtcgct gtcgggcaga ccatcaaggt caactacacc ggcaagctgc tcgacggaag
    12841 ggtgttcgac acttcatacc tcactgtggc caacgatgac gccaactacc ccaagaccct
    12901 ctcgttcacc aagcgcagca attcgtcgta cacgcctcta agcttccagg tcggggccgg
    12961 gaggatgatc tccgggttcg acgcggcagt ggtgggcatg aaggtcgggg agaccaagac
    13021 cgtcacccta actcccgatg aggcctacgg ggacatggac ccctccaagc tggtgacctt
    13081 ccaactgacc gagaacgtcc cgctgctgaa ggtcttcacc tccagcgcct tccaggccga
    13141 gtacggtgtg gcccccgctt accatctgat ggttagcgat ccgaggtacg gttgggacgc
    13201 gatcgtggag gcctatgacg aacaggccga ccgcgtgaac gtaaagaacg ttccgacgat
    13261 cgattcgcta taccacatct acggtacggg cagcgtgggc tgggacgtca aggtcatggc
    13321 catggacagc agctccggcc tgataaccat ccagcaccaa ctggacgatg gtgacagtga
    13381 catgataaag gggttggacg gtaccagcac cttcttcatc accggcgtgg accaggacgg
    13441 cgggaccgcg atgcggaact ataacaccga gctgctcggc aaatcgttgg tgttcaccat
    13501 aaccatcgtg agcatcgtcg attgatccca aaccccaacc ccttaccttt cttctattgg
    13561 gacaaggtct ctccgccctg cttgtccgcc tttcgctttc gatagctgga ggcgatgaag
    13621 ctgaggacga ttatgacgac caccatgacc agggtcacgt cggcggccat tcccttttcc
    13681 atatagatca ggaaatagtt gcttgcggcc aatatcagtc cgtacttcag cgttcctccg
    13741 agcaccaggt agaacagcga tctccggtag gaccaaccag atagtgccac gaaggctccg
    13801 gtgaaaggca ggatcggcgc cacccggttc aacaatatca tccgctcgtc ctgcagcagc
    13861 aggaagcggc ggtatcgttc gatcacccgg gatatctttg gcgggacctc aagccgcttg
    13921 accaccaggt agagcgtggt tataccgagg acctcggcaa gcgcgatgac cagaacgaac
    13981 atggaccaca aggcccaatc gggcagggtg ccataaccgg cgatgaagaa cagcactacg
    14041 aacagctcag gcagcgtcgg gaaaactatg gcgtcgatgt agaacagcag aaatgtgcag
    14101 agcaaccatc cggccaggcc taggggtgag aacagggtgt aaaaggcctc gccgacggag
    14161 aacatcctat ctcccgagcg ctagtgcttt aaaaaaactt tgttgttgac ccgtccagcc
    14221 ttggactcca cagcgtacct atagatgtcc agcagcctgg tggcccattg ccccgccgaa
    14281 tactcgcccg ccctggctag agccccctcc cggtacttca gggggtcctt gagcagacgg
    14341 gaggtggcct gcgaccagct atagggggtc tcctcgaaca gctctccgtt ctccccctcc
    14401 cttatgagct cggcgacggc ccggtagcgt attccgctta ccggctttcc aacggccatg
    14461 gcctccagta ccaccagtcc ctgggtctcg aacttgcttg ccagcgtaag aacgtcgcaa
    14521 gcggcgatgt actggggtag ttcctcatcg ctcacgaagc cggtgaaggt gaccttgtcc
    14581 gctaagccca gctcctcggt caatcggacc aggtgctcct tggccgggcc atctccgacc
    14641 aggaccaggc gggcgtccgg ctcctgctcg ctcagtatgc tgaatccgcg caggaccagc
    14701 tcgatgttct tttcccaggc gatgcgtccg agatgaagca cgatcttctt gccctccaga
    14761 ccgtagcgtt tcctgacctc gcttccgtcc agcttaggat tgaagcggtc caggtccacc
    14821 ccggtgggga tcacctcgaa acgttttatg tgcggagcgt agcgtttgat ctcgttcttt
    14881 atggccaagg tgggcgctat gaccacctcg gctcggtgca ggattatcct cagatagctc
    14941 cacatcccca gctggatcac ccattccggg aagggggtga agttgtagaa cttggccgcc
    15001 tcggttacca tggtgtggaa ggtcaggacc actggctttt tcagggcgcg accggcgagc
    15061 atggcgcgca cggcctggaa catgagcccg tgcacgtgga tgacgtccac atccagcttg
    15121 gccagtatgt ggcatttgtc ggttgggaat attgggatgc ggtatccaga atactgttgg
    15181 aaaccgatgg agcggaaata gtggacgccc tcctccctat ctgccgggtc ggccgggtcc
    15241 ggggctagta tgtaaacggt gtgacccatc ctctctagct ccctcttggt gagcagtagc
    15301 gagttcacca ccccgtcacg ggtgggaagg tacgagtcgg tgaacatggc gatcttcacg
    15361 ggttctacct cacctcatga gcttttctat ctttccaagg acctcttccg ggtcccggcc
    15421 gagcaccctg atcatcggtt cctttcccac tcccccgcgg tcgaagatta cgtctggaac
    15481 atgaccgcag cgctcgatcg cctgtgcggt cccccattcc atggaggata cgctctccgg
    15541 ttcctcggtc cgatcgaagc taccgatatc tagactgaat gatttcaggg cggccaaggt
    15601 ctcctccgag tatcgcaggt tcatcacgca acggacctct ggatcggccg ccgtggcggc
    15661 catcaccacc cgggctatat gtcggctccc ttcgaaccga acctcgcccg cccggcgaat
    15721 gtgctggccc actctcacca gtcgcccttg gacgccgcat atctcccgat atccctgtgg
    15781 atagggcagg gcataggcca ggttcatgcc cacctccggg accagttcag gcggcagacg
    15841 ctgttctatg gtctccaccg cggaacggac ctcctcgacc atccggccgc tcatcgcttc
    15901 cttgtacaag gtggccatgg ggtttatggc cagcagcccc ttgcccaccg gaagggccat
    15961 ggctatcgag tcgtatattc gtcgcttggc ctcctgcacc gcctccttgg gctcaagtcc
    16021 caatcccagc ccggcggcga tgaacgagga gagggtgcat cccgccccgt gcaccttgcg
    16081 gtccaggcgg ggcgatacca gctccatgac cccttcctcg gtgaagaaaa ggtcgcgagc
    16141 catgttccca tccagatgac cgcctttcag caggaccgcc tgcggtccca gtcccagaag
    16201 gatgttgccg acctcctcca gcgatcgatc gtcggtgatc ttcattcccg atagcgtctc
    16261 ggcctcctca cggttcgggg ttaccaccgt ggccaaggga aaaaggtcct tggccaggga
    16321 ttccaccagt ccttccttgt gcaatgaggc tccgacacct gcgaacagta ccgggtcgat
    16381 gaccaacggc accttgagct cagtgagcag ggaggccacc gcacgcaccg tgcgtgccga
    16441 atggagcatt ccggtcttga ccgcggagat gcaggtgtcc tcagctacgg cggtgatctg
    16501 ggcggtgacc tgttccgtcg gcaagggaaa tatctcccgt agccgcaagg tgttctgggc
    16561 ggttaccgcg gtcagtgcga cggcggcgtg cgctcccatc gaggagatgg ccttgatgtc
    16621 ggcctccacg cccgccccgc ccacggaatc ggaacccgcg acagtgagga tgatcgccat
    16681 agacggtgta atggtcgcct tcctaataat tataacaggg cgtggcggtc tccgtccgcc
    16741 aacaaacatt atatatcgag ggccgctgtt cgaaaaacac gatgaaagcg agcagtgggc
    16801 acttggtgtt gaacacccgc acagaatacc aggagttggc cgaggtcttc cccgagctgc
    16861 tcaagctatt cttggaagag acggatcagg tcccggagga cccggagatc atgcagatgt
    16921 tcatccacct taaccagatg gacctggagg ccaaccgcaa gccggaaggc tacaaccgca
    16981 agggacgcat gcgattgatc tttccgacca accgcatgga gttctacgtg aaaggttcgt
    17041 ccaagagcgg agaggtggtc cgcgtggcgg agaagatcag caagatgctc acgaagaacg
    17101 ggttcgagca tgagctggaa tggaacaccc tatcctgcct ggagctttaa actacttcct
    17161 cagttcttcc caaacatcgt ccaggcggat tatctcgctc tcgcattccc cccggtggga
    17221 tgccaatatg gtctgggccg ataacagctg ctcctgcacc ctctccggtg ccgtgccgcc
    17281 ggccgaagtg cgccggcgca agcaggcgtc cagggagatg aactccaggg atgttttatc
    17341 cagaagctcc gagaatccct tcagttcctt gatggtgagc gaatcgagcc tcttcccctt
    17401 cttcacgcaa tgttgcacgg ccgcccccac cacttcgtgc gcctgccgga agggcatccc
    17461 cctctgcaca aggtggtcgg ccaggtcggt ggcgttgagg aacccgtccg cgcacgcctt
    17521 cgccatgcgt tcccggtcga aactcaggtc tcggtacatg gggccgatca tgaaaaggca
    17581 ggaagtgagc gtctcgtagc tcgagaagac cgaccccttg tcctcctgca tgtcccggtt
    17641 gtaactgagc ggtagtccct tcatcacggt gagcagctgc atcaggttcc cgatggcgat
    17701 cgaactgcgt ccacgaacca gttccgccac gtccgggttc ttcttctgcg gcattatgga
    17761 gctgccggtg gcgaaggcgt ccggcatctc ggcgaagcgg aactccgggg aggtccacag
    17821 caccagctcc tcgcccatgc tgctcaggtg caccatggtc tgagcgcagt cataggcgaa
    17881 ctccagggcg aagtcccggt cgctcacggt gtccatggcg ttatcggtcg gacgatcgaa
    17941 gcccagcagg gtcgaggtca tcttccggtc tatcggatga ccggtgccgg ccaaagcccc
    18001 cgctcccagc gggcactggt taaggcgttt gtaggcgtcc aggaacctct cggcgtccct
    18061 ctgcaatcgg aacacgtgcg ccagcagatg gaatcccagc gaaacgggct gggcatgctg
    18121 caggtgggtg aaaccgggca ttatggttat agtctccttc gccgcccgtt cgagcagttc
    18181 ggactgggcg tctaatatga gcgttacgat ctccagtatg gcgtcgcgca cgaacatgcg
    18241 gaagtccgtg gagacctgat cgttgcggct gcgggcggcg tggaggcgct ttcccgcctc
    18301 ccccaccctc tggatcagga tgtgctccat gttggtgtgc acatcctcca gttcggccga
    18361 gaagtccagc tggccggatt ccagatcgat cagcagctgc ttcaggccgt tcgagaggac
    18421 ctcggattcg tccttcccga ttatcccggt cttgccaagc attttcgcgt gagccaatga
    18481 accgacgatg tcgtaccagg ccagcctggt gtcgaccgaa agggacgacg tgaacgacaa
    18541 tgtcatttcg gatggacctt cggcgaaacg acctgaccac agctgcttct cgaccatatc
    18601 gatcacttct tctgggcctt ggccacgcta cgcaacggaa gaccccacac gtagatgaag
    18661 ccctctgcgg acttgtggtc gaactggtct ccctcggcgt aggtcgccaa tcccgtatcg
    18721 tacagcgagt acggcgagga acggcccact atggtggcac tgcccttgta gagcttgacc
    18781 cttacggtac cgtcgatgaa ctcctgggtc ttgtcaatga atgcggtgag cgcctccatc
    18841 agcggggaga accatagccc gtcgtaggcc agctcggaga agcgctgttc gatcccccgt
    18901 ttgtagctga agacgtcctt ggtcagaacc atcttctcca ggtccttgtg cgcatttatc
    18961 aggatcatgg ccgccggaga ctcgtaggtc tcgcgggact tgatgccgac gaggcggtcc
    19021 tcgatctgat cgatgcgacc gtaaccgtgc ttaccgccca gctggttgag cttctttatg
    19081 atgtcggtca tggacatctt cttgctcttg ttgagcccga ccggcaatcc cttcttgaag
    19141 tggatctcca catattccgg cttgtcggga gcgtccatgg ggtccacggt ccactcgtaa
    19201 gcgtccttgg gcggctcctc catggcgtcc tccaggatgc cgcactcgca gctccgtccc
    19261 cagatgttct cgtcagtgct gtacgggcat tccttcttga ccttgatcgg cacgtcgttc
    19321 ttatgggcat actcgatctc gtcctccctg gtcatgaccc attcccgcat aggggcgatg
    19381 atcttgatct ccggggcgag ggcggctatg ctcacgtcga agcgcacctg gtcgttgccc
    19441 ttggcggtgc agccatgggc gatgaacttg gcgccctcct tcttggcgat gtccaccatt
    19501 atcttggcga tgagcggcct ggcgatcgac gtggccaggg gatacgtccc catgtacagt
    19561 gcgttggcct tcagggacgg tccgatgtag tcattaacga aatcctccgt cgcgtcgatg
    19621 gcgtaggcct gcaccgctcc gatcttgagc gcgcggtcga cggcctcctg gaggtctcca
    19681 ggctgtccaa cgttgatgct gacagcgatg acgtccagat cataattctg ctgcaaccac
    19741 cggatggcca cggacgtatc cagacctccg gagtatgcca gcaccacctt ttcacgaacc
    19801 ttcttagcgc gagctgccat atgaatctgc ggcgatgaag cgaacctgta tattaatcag
    19861 aattggcgga agcgggacat tgttcgttcc ttgtgttcgt aatcggacag ccggtcacgt
    19921 tgtcgaggtc catagccgcc tccggggcgc tgccagatat gacgcatatg gaacatacct
    19981 ggtcaaaatg tcccgtttcg ggcataatgc ttaataaaca aactcttaat tcggcaaact
    20041 ctcatattgg acgaggaagc agaatgatca aggcagcggt ggtcgggggt tccggttaca
    20101 taggcgggga gctggcgcgc ctgctcagcc gtcatcccaa gatctccctg gaggcgataa
    20161 cctccaggca gttggccgga cagcaagttt cagacaccca tccgttcctg cgtggctacg
    20221 tggacctcaa gttcagcgag tccataaccg gcgatgggtt cgacgttgtt tttctggcaa
    20281 caccgcacgg cgcctccatg aaattggcgc cagagatagt tcgaagcggg gccaaggtca
    20341 tcgacctcag cggcgattac cggctcaagg accccgcgac ctacaagaag tggtatgggc
    20401 acgagcatac cgacctggaa aacctgggca aggccgtcta cggtctgaac gagttgtact
    20461 gggacgagat agccgaggct gatttcgtgg ccaatcctgg ctgctatccc acctgctccg
    20521 cactgggatt ggcccctctg ttcgccaacc acttggtggc gggcggtgtc ataatcgacg
    20581 ccaagagcgg aacctccgga gcgggggtcg agccgaccaa ggccactcat catcccaatt
    20641 gcggggcgag cgtgaacccg tacaaggtcg gaactcaccg ccacaccccg gagatcgctc
    20701 aaacgctcac caggctgcag ggcaggctgg ccgaggtggt cttcactccg catctcatac
    20761 ccgtggtgcg cgggatgctc tgcaccatgt atctcaagct caacgacgac ctcaacaagc
    20821 aggaactgct gggcatgtat accgagttct tccgtaggaa gcgcttcgtg cgcatgaccg
    20881 atgtaccatg gatgcaggcc gttatcggtt ccaaccattg cgaggtgggg ctggagatgg
    20941 ttggcgacag gaacgtggtg gtcatgagcg cgatcgacaa tctggtcaag ggaggtgccg
    21001 ggcaagcggt gcagaactgc aacgccatgt tcggatggag tgaggagacc ggattggatt
    21061 ttccaggatt gggggtttaa aaatggaagt ttttgaaggt ggcataacct cgcctaaggg
    21121 tttcaaggcg gctggagtgc attgcgggat aaagaaggag aagctcgatc tggcggtcat
    21181 ctattccgag gtacccgcta aatgcgccat cgcctacacc cagaacaagg tgcgggcggc
    21241 accgatcgag gtcatgatga agaaggaccc caagaccttg caggccctgg tgatcaacag
    21301 cggcaacgcc aacgccatca ccggagtgca ggggatctac gattccaagc agatggtgtt
    21361 cctcaccgcc cagacccttg gaatccgcga tacgctcgtg ggcgtggcct ccaccggggt
    21421 catctcccgc ttcctgccca tggataagat atccgcaggc atacccaagg ccgttcagtc
    21481 gctgggaaag ggtccggagt ccgatgacct ggccgcaagg gctataatga ccaccgacac
    21541 cgtgaagaag gaagcctcct gcagggtgac cctcaaggac gggacggtgg ccaccatagc
    21601 gggcataacc aagggcagcg ggatgatctc cccggccatg aaggtgctgc acgccactac
    21661 gctcacgttc atggtcaccg acgcccacct cggaaagaac ttcaaccgcc gctggcagga
    21721 tatgatggac gtcagtttca acgtgataag cgtcgacggg gaccagagca ccaacgacat
    21781 atcggtgttc ttggccaacg ggatggccgg tggcaagccg gcggatgacg acccggcctt
    21841 ctgggaaggc gtccgatata tcgcccaaca actggccaag aagatagtca tcgacggaga
    21901 gggagcgacc aagctcatcg aggtcatggt gcacggggcc aagaatcccg tccaagcgcg
    21961 gtcggccgcc cgggccataa tcgcatcctc tctggtcaaa acggccatct tcggggcgga
    22021 ccccaacttc gggcgcattc tggccgcgtt aggaaactcg gacgcggagt tcaatctgga
    22081 aaaggtaaaa ttggttttgc gttccaacgg cgattccgtc accctcttcg aggatggggc
    22141 gccgacgttg gtcgccggca gcgatgtgga ggccgccgcc aagagggtcc tatctcacaa
    22201 gaagatagtc atcgacctgg acctgaacaa cggatactcg accggagagg cctggggctg
    22261 cgacctcagt tacgactacg tcaagatcaa cgccatgtac accacgtgat gagatgccgc
    22321 gcatttcaga tgttggcgtc ccgcgccaag cgggaaaggt ggtggtcaag ttcggcggtt
    22381 cttccatcgg agggatggag cagatagacg ctttcgcgaa gcagatcgcc gagctgaggg
    22441 agcgcggcct tacaccgatc gtcatgcacg gtggcgggcc ggagatcacg gacgagatga
    22501 aacgttgtgg actgccggtg aacaaggtcg ccgggctgcg gatcactgac gacgcgacat
    22561 tgcagatagc gaaatccgta ctgtcccgca tcaacgaccg ggtcgtggtc tcgttacgca
    22621 aagccggtct caaggccata ggggtggccg ggagcgaggc ggacacattg gtggcgaaaa
    22681 agatggaccc ggtaaagctg gaagggcccg acgggacgaa gatggtggac ctgggtcacg
    22741 tgggcgaggt ggtcagggtg gacccccgtc tggtgaacgc cctatgcgac aagggcttcg
    22801 ttccagtggt ctattccatc tgcgctgacg attccgggat gctgatgaac gtcaacgccg
    22861 acaccgccgc ggccgctctg gccgccggta tcgccgctaa ggacatggtt ctggtcaccg
    22921 acgccccagg ggttctccgg gtcttcgagg accgcggttc caccattccc gaaataaagg
    22981 agtcggacct ggggccgctg acctcctccg gcatcttgaa ggacgggatg atccccaagg
    23041 tcgaagcctg cttcatggcc ttacggggcg gcgtgggcac ggcgcacata atatgtggta
    23101 cgacccccaa ctccatcgtg gaccagttgt tcagcggcag gaatctgggg accaggttga
    23161 cccgatgagg ttttgacatg gacagcaaac aggttgcgga actgagctct tactatctat
    23221 tccagaacta tggacgcgaa gccatatgct tctctcatgg ccagggggag cacctctggg
    23281 acctggaagg ccaaaggtac acggactacg tggccggcat agcggtcaat tgcctcggac
    23341 acgcccatcc tgaattggtc agggccatat cggagcaggc ctcccggctc atccacgtct
    23401 ccaatctcta ccagatcaag gagcaggcgg acctcgggga ggccatggcc tccatagtcc
    23461 cttcgccctt ggggcgttcc atgttctgca acagcggggc ggaggcgaac gaagcggcgc
    23521 taaagctggc ggtgaagcac accggacgcg gcaaggtggt ggcctgtcgt aactccttcc
    23581 atggaaggac gtctgccacc ctgtccgtaa ccggccagga gaagtaccag aaggggttcg
    23641 aacccttact ctcgaagaac gtcgatttca tcaccttcaa ttctatcgag gagcttaaga
    23701 acaaggtcaa cgggaacacc gcggcggtca tactggagcc agtgcagggg gagggcgggg
    23761 tgctgccggc cgaccgggaa tacttccgca ccgtacggga cctgtgcacc gactccgggg
    23821 cgttgatgat cgtggacgag gtacagaccg gcatgggacg aactggcaaa tggttcggct
    23881 tccagcattt cggcgtggtt ccggacataa tctcgctagc caaggcgctt ggcggagggg
    23941 tgcccatcgg agccatcgtc actacccccg acatagcgaa gacgttcacc cctggtacgc
    24001 acggtactac tttcggcggg aaccccttgg cctgcgcggc cgccaacgcc gtgatacgca
    24061 ctatgaagag ggacaaactg gtggagcgcg cggccgacct cggcgagcgc tggaggtccg
    24121 agctacggaa cgtcacttcc ggacatcctg aggtggccga cgttcgcggc ctcggtctca
    24181 tgatcggggt ggagatggga gacctggcca aggagttcca gaggttcgca ctctccaaac
    24241 ggcttctggt caacgtcgcc ggcggcaagg tcttgcgcct ggttcccccg ctcataatct
    24301 ccgaggcgtc catcaacgac ctgaactccg ccctccggga attcctaaaa tgaaatgtct
    24361 gaaaataaac aataaataat ccgctcggat tatccggggc gatgaaggaa gtcccccaga
    24421 aggagagcgt ggccgagcgg acccgggcat acatcgacgc gcatccctcg gtcaaggact
    24481 gcatggccaa ggacctgatc aactattcct ctttggccag gctgatcatg aaggacctgg
    24541 gcattaagaa cgaggaggcg gtcatgatcg cctgtcgtcg ctacgcccag aagctttcag
    24601 tacgtgatca cgagggggat atcctggcca ttctcgccga cagccgtctg gaagtgaaga
    24661 cgaagatatg catcgtcacc gccagcaacg attggacggt gctgcaacgt ctggagcgcc
    24721 tgttcaccaa gctcatcaac cagaaggccc tcatgcaggt catacagggc gctcaggcca
    24781 tcaccatcat cgccgacgag aaattacgca acgaggtggt gaacgatgtg ggcgagacca
    24841 acgtcctcaa ggttcgggag gacctggtcg agatcaccgt taaaagtcca cagaagatcg
    24901 gggagaccag cggagtgttc tcctatctgg cttctaacct atcggagcag ggggtgaaca
    24961 tggtggagac cgtttcctgt tacaccgaca ccatcttcat cgtgcacgag aaggacatga
    25021 tacaggccta ttccctgctg tcgaacctgc tggagagcgc ggagaaggcc accgaagcgg
    25081 cgcattaacg ccacaaagcc atttatgcgg tgaagcctta tcagcggccg atgaagaacg
    25141 atcctaaagg gaaggtgccc ctggtccgga cggacatccc aggtccgctg ggaaggagca
    25201 tagtcgatct ggacgaacag tatctggcca ccgtgaccaa atcggcaccg ctggtcgtgg
    25261 accgcgccct ggacgagagg gtgtgggatg tggacggcaa cctgttcctg gatttctcca
    25321 gcggcgtggc cgttctgaac atcgggcatt gccatcctgc cgtggtcaag gcggtgcagg
    25381 agcaggcggc caaggtcatg cacttcgcgg gcaccgatta ctattacgat gtacagtccc
    25441 gtctcgcgga acggttggcc aagatcgccc ccggtcccgg cgagaagaag gtcttcctca
    25501 gcaacagcgg ggcggagagc atcgaggcgg ccatgaagct ggctcgatgg tcctccgggc
    25561 ggaagcagtt catagctttc ttcggcgcct ttcacggtag gaccttaggt gccctatctc
    25621 taaactgcag caagcgcgta cagcgcgcca agtactttcc gacggttccg ggcgtcactc
    25681 acattcccta cgccaattgc tatcgttgcc cctaccatca ggagtacccg tcctgcgggc
    25741 tatggtgcgc caagatactg gacgaggttt atctggacgc tctgctcccc ccggacgagg
    25801 tggcggcgct gttctttgag ccggtccagg gcgaaggcgg ttacatcgtt cctcccaagg
    25861 agttcctgac cgagatatcc cgaatatgcc gttcgcacgg cattctgacc gttgatgacg
    25921 aggtgcagtc gggcatgggg cgaacaggaa ggatgtgggc cgccgagcac ttcggcctgg
    25981 agccggacgt gacctgnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    26041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnatga
    26101 tgagggctct ggagtttgtg gaggaccgga gcacgaaggt gcctgccgtc aagcttaggg
    26161 acgacgtcgt ccatgccctg ttgaaaaaag gcgtcatagc tttgggctgt ggaaagtcca
    26221 gcatacgcct gatacccccg ctgaccataa gcgaggagaa tctggacacc gggatgcgtc
    26281 tgctcgagga gagcattggc gcagttgtga gggataggaa atgaagcatc tacccaggac
    26341 caaatacgag gaggtctccg gggacggtta tctgaagagg atcgtcctgg aggccaagga
    26401 catcggactt aaggacacct tgttgcagga agtgcagttc accgccgggg agaaggtggc
    26461 cttccacttt caccaggtca cccgcgaaat cttctactgt ctggtggggc cggcgccctt
    26521 cgttataaac ggacagtcgg tggtgatgaa cgaaggtgac tgcgtcatct gcgaaccggg
    26581 cgacgtgcac gggaacccgg tcatcggcaa cgacttccgc atactcgtgt taaaagtagg
    26641 cctgaaagag cacgacacgg tatggctgga cggttgatcc gaggggatcg aacgttcgaa
    26701 gaacgggaag atggagccac tagggagatt tgaactcccg gcctgctgat tacaagtcag
    26761 ccgctctacc agctgagcta tagtggcctg ccatctggaa cgtcattccg gatataaccg
    26821 tttttatcaa cggtccaagg tccgccagac ctcttcctat tgataacgat taaataaatt
    26881 cgtgttatca tagcgcgagg tgcgcccttg gacgctaatc tcgaagacaa gccggaaaag
    26941 agggtcctga tggacctgac cgccaaccca gctccattgg ggcttctggg tttcggcatg
    27001 accaccgtga tgctcaatct acataatgct gatctcatcc ccttgagcgg ggtcattctg
    27061 gctttgggaa tattctacgg agggctggga caggtcctgg tcgggttgat ggagtggaag
    27121 aaaggcaaca ccttcggaat ggtggccttc acctcctatg gactgttctg gctcaccctg
    27181 gtgggcatct ggaccttgcc gacccttggt ctgggcgaac cgaccgacaa ggttaccatg
    27241 ggctatttcc tgaccatttg gggcatatac acgatgttct tcttcctggg caccatgaag
    27301 agcaaccggg ccacccagtt cgtgttcggc tcgctcaccg tgctgttctt tggtctggct
    27361 ctgggtgact tcaccctgat caaggagatc accatcgcct ccggttacat cggcctggta
    27421 tgtggcgcct cggccatcta caccggtctg gcgaccgtgg tcaacggggc gaacggtaag
    27481 gtcatgctcc ctctgggcgt gcgcaaatag aaccataaaa ccacttactt cccccttttt
    27541 acgattggcg gagacgcttt tttatacggc gagcggtgat gaacgacggt ctcgccgata
    27601 tcggcgttca ggtgacgttc atggacaagg actcgttgaa attcctgcag gagctttgcg
    27661 atgtgcccgg gccttccggc ttcgaggccg cagccacccg gctgatgaag aactacgccg
    27721 aaggctattg cgaccgggtg ttcaccgaca agctcggcaa caccatgttc gaaaaggtgg
    27781 gtcagaagga cggtcccatc gttcttctgg cggggcatgt cgacgaatgt ggcttcatca
    27841 tcaccggggt caactcccaa ggatatctgg ccttcagcca gctgggcgga tggttcgacc
    27901 aggtgctgct gggacaacgt gtgctggtgc acacccggaa gggggtactg aacggggtca
    27961 tagcctgcaa gccccctcat ctgatggaac cggaggaggc caagaaggtg gtgaccaagg
    28021 acaagatgtt cattgacgtc ggggcgtgca acaaggacga ggcgcaggcc atgggcgtca
    28081 ggctcgggga cgcagtcact cctgactcca agatgttctc cgtggagaag caggcctata
    28141 aggacggaaa gccggccgga aagcgtacca tcatgttcgg aagggccttc gacaaccgac
    28201 tgggagcctt cgcggcggtg gagttgctga aagcgctgaa gaaggggaag gtgaggcacc
    28261 ccaaccaaat agtgtcggcc gccacagttc aggaggaggt cggattgaga ggcgccagga
    28321 ccgtggccgc ctccaccaat cccgacgtgg ccatcgttct ggacgttgac atcgccgggg
    28381 acgttccggg aatagatccg ttgcaagccc ccgcgcgaat gggggagggc gtctccataa
    28441 ccgtctacga cggcaccatg ataccgaacc agccgctcaa ggaactggtc atctccatat
    28501 gcgagaaaag gaagatcccg caccagctgg catacgtcat cagaggaggg accgatggcg
    28561 gtctgatcca tacctcccta accggagttc ctaccatcgt catcggagta ccgacgcgcc
    28621 acatccactc gcacgtggga ctgttcgaca ccgccgacat ggaggcgtgc atgaagttga
    28681 tcgttgagct ggtcaaggtt ctggaccgga agaccgtgga ctcgctgacc gcgatctaaa
    28741 tgaatcatcg atccttggcc gggcggtcct ccccgatctc ccgaccaggc ctttcccggg
    28801 cccttctccg acgatcggtg ttgtcctcca ggagctcctt ggtgtacttg cggtggcaca
    28861 ccgagcaaag cgtcctcaga ttggccgggt gctcggtgcc ccctcgtgat ctcggaacga
    28921 tgtgatggat ctcgtaaggg acgcgcctcc cctttacctc tattccgcat tccgtgcagc
    28981 gaccgccgtc ccggcgtttc acgtatcgcc ttatccttct ccacagccag ttgcgcacct
    29041 tatcgtggag ttccgatccg ggtcctattg aaaggtattc ctcggtggtc ccttctggcc
    29101 tccaggcctt ggtctccttg gagcggtaga gcgccaggaa gttatgccac gacaggcagg
    29161 tctgatgcgc ctgctcctct cggtgcttcc ggccacatgc ctcgcactcg gtccagaagt
    29221 ttctgtccgg ttcgcatttt aacttgggcg cccactctct gaacggacag atgtctgtca
    29281 tctcatcatc gcaatgcaga tgtatcgaaa ggtccagacc gcttaggcga tcatctcgga
    29341 aaagcgtgcg atgttctcgg tacctatccc tagacccgtt atgcagatgc atgagatagc
    29401 aggaggacgg ccggttcctg accaaacggt gatcgcagag cttcatgagg ttccaaacgc
    29461 agtgagcgcc tcgcaccgaa gccatgcgct cgaggtcttt tacacctttt ccccgctcca
    29521 ctgaaaatga aaagaaccga aaagggaaaa ggcatgctca gttggctgct atggacattt
    29581 agaatttcta tgttccacac gccttcctga acgtccgaaa gatataaaaa gaggaaatca
    29641 atcaaccagt tcgcctaatt agcattactg gtgaatctca tgaccactaa atcttcgatc
    29701 gtaaaggtct ccaagggtga catcgtccac gttgaataca acgcttacct cgccgagagc
    29761 ggtatgctct tcgacaccac caacgcggac aaggccaagg aggccgagat cttcaacgag
    29821 aacctgacct acaagcccct gcccctgcta gtcggcggtg gaagggtatt ccccggtctg
    29881 gacgaggcct tggccgaggc caaggtagga gagctgaccg ttgttgagat acccgcggag
    29941 aaggccgccg gagcccggga ccccaagctg gtcgagaaca tcgccctgcg cgagttcttc
    30001 cgccaggaga tccgcccgga gatcggcatg gaggtcaaca tgaagaaccg cgtgggcacc
    30061 gtggtcgccg tgaccaacag gatggttcgc gtggacttca accgccgctt cgccggcgcc
    30121 gccctgaggt atgagttcac cgtactcgac aaggtcgagg gagatgaggc caaggtcatg
    30181 tccatctgcg agatggacta cagtaccgcc gagggcttcc gggccatcgt caccgaggga
    30241 aaggtagttc tctacctccc ggacgtctgc aagtacgatc agaagtggct gctcaccaag
    30301 tacaaggtgg tcgccgatct gcgcgatgcc tttggagcag tcaccgtcga gctggtggag
    30361 gagtacctca agaaggagga caagcctgta gaggtcgctc ccgccgagct cgctgaagag
    30421 aagtctccag aagagcttta aaccacttac ttcggaaaca ttttaaatat cttatttcta
    30481 atcaacggaa cgcacgggcg ggtggcctag tctggatatg gcagcagcct cctaagctgc
    30541 aggtcggggg ttcgaatccc tccccgctcg ctttctcgtt ct
//
LOCUS       DAOPZI010000018        28611 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1638_length_28611_cov_9.192954, whole genome shotgun sequence.
ACCESSION   DAOPZI010000018 DAOPZI010000000
VERSION     DAOPZI010000018.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 28611)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 28611)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28611
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1638_length_28611_cov_9.192954"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(3..86)
                     /locus_tag="PKM11_04835"
     tRNA            complement(3..86)
                     /locus_tag="PKM11_04835"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48..50),aa:Leu,seq:taa)
     gene            complement(157..1005)
                     /locus_tag="PKM11_04840"
     CDS             complement(157..1005)
                     /locus_tag="PKM11_04840"
                     /inference="COORDINATES: protein motif:HMM:NF017536.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HNX47866.1"
                     /translation="MSSIREVAKLIHGQSTHDGAGVKLTRMFSRDEAALLDPFLMLDH
                     FGSDRPEDYLAGFPMHPHRGIETVTYMLDGNVAHKDSLGNHGVIGPGDVQWMTAGSGI
                     LHEEMPQRAKGWMQGFQLWVNLPKANKMMPPRYRDLKKEDFPVFDLGNGSSIKVIAGE
                     SQGLVGPVKDLVVDVKYLDITLNSRTVLEHEVPAERNAFVFVYEGEMLVGDKDARTVP
                     AGSVAVLGEGDSFRFTVGRRPTKFMFGSAKPLKEPIAWGGPIVMNTREELDHAFSDLK
                     RGTFIK"
     gene            1071..1253
                     /locus_tag="PKM11_04845"
     CDS             1071..1253
                     /locus_tag="PKM11_04845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47867.1"
                     /translation="MPKEKRKIIWHCANGHDFEVEDELQRSICPVCGGNDVERASKDK
                     EKQRPPRGSLRSWFWR"
     gene            1257..1832
                     /locus_tag="PKM11_04850"
     CDS             1257..1832
                     /locus_tag="PKM11_04850"
                     /inference="COORDINATES: protein motif:HMM:NF024769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI/OmpD-associated family protein"
                     /protein_id="HNX47868.1"
                     /translation="MNTKGDRKEREFLWFPSVEDWEEWLAKNHDRSSGIRIRFFKKAS
                     GKASVDRQEALEVALRFGWIDSVLNNYDQDSYLQRFSPRKKDSHWSRVNLETAEKLMA
                     EGKMTEAGLRALGDLKKRYESLKEEDSIDLDLNGLFRDDPETLAAFNALPPSHRKTYG
                     RYILSAKLPETRERRMKRVTPMIRERRPPIL"
     gene            complement(1844..3202)
                     /locus_tag="PKM11_04855"
     CDS             complement(1844..3202)
                     /locus_tag="PKM11_04855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic 2,3-diphosphoglycerate synthase"
                     /protein_id="HNX47869.1"
                     /translation="MKKSKIVIMGAAGRDFHNFNTYFRNNEKYHVVAFTAAQIPNIEG
                     RCYPASLAGHLYPTGIPILAEDDLPSIIRKNKVDQVIFAYSDISHVELMHKASWVLSL
                     GADFRLMGNSAITLRGNQPVISVCAVRTGAGKSQTTRKLCRILHDRGLKVVAVRHPMP
                     YGDLTKQAVQRFGEYADLDKHDCTIEEREEYEPLIENGIVVYAGVDYERILREAEKEA
                     DVIVWDGGNNDLPFFESNLHIVIADPHRAGHEISYHPGEVNLRLADVVIINKVQTADR
                     RNILKVKENILKYNPKSIVIEAASPIKVDDPSMIKGKRVLVVEDGPTLTHGEMAFGAG
                     TIAAEDNGALDIVDPRPYAVGSIKELYEKYRHLGPILPAMGYTDEQIKDMEETINKAD
                     CDVVVAGTPVDLRRVMNVNKPIVRVHYELAEIGKPTLEDILDEKLGPILFACHGDSCK
                     VM"
     gene            3492..>3907
                     /locus_tag="PKM11_04860"
     CDS             3492..>3907
                     /locus_tag="PKM11_04860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HNX47870.1"
                     /translation="MKIPERPRSLQDIFKDKIIKNPVFTEDRTVSDRVKQFNEDYLHW
                     DEVRRKDMPQDPEVVWALMKMSRQGQSRHVAFLNTSLTYNTTSRSQRIMHMLDTTASG
                     LLVLEEPLKDSEMKRYVISSLMEEAIASSQLEGAVTT"
     assembly_gap    3908..4007
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            4371..4817
                     /locus_tag="PKM11_04865"
     CDS             4371..4817
                     /locus_tag="PKM11_04865"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47871.1"
                     /translation="MVYRIPSVKVLEDSIRKVIREQQSIPSQRLFTELVLEDLHKKNP
                     EYKVGEVRLRRMALHRNLAKVTISYRETKDPSHKGRCPVCCSPIEELHNFTLDEKKVE
                     LGFKCTKCPYWTGPRRRVPVRYNFTMFGAIVPPSKKKGKFAQWKFA"
     gene            4854..5057
                     /locus_tag="PKM11_04870"
     CDS             4854..5057
                     /locus_tag="PKM11_04870"
                     /inference="COORDINATES: protein motif:HMM:NF021636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HNX47872.1"
                     /translation="MCRSTVYMSTKEGVLELVKNAVRLNLDDEVLVIIDDVGERLELQ
                     NVRIKEVNLISNNIVLAKDPSEN"
     gene            5205..6173
                     /locus_tag="PKM11_04875"
     CDS             5205..6173
                     /locus_tag="PKM11_04875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47873.1"
                     /translation="MRIKRQYMAVILAVMLVISSLAAFVAYESVQRNRLGYIGIEVDK
                     EVFTSEEDVTFRLVSLSRNAEFNITDRWNDDVDDDFYRGLDLVRVPDIMDAETFLDDL
                     SSLDYLRNHNTYVPLGRAFFDHFDSQDDSLQVTWNGTVVKEYWDGNGSFLRYSPAVSG
                     FYVIVPRNSWSADHKVSFLVNERSVFYYDSLDVGMKVTNHIEEDVTVELTLRAPPWTI
                     DNVTCDLDLVLYYQGSIFEPAEDEDAHHYEEKSIVLNPGQDRVRTLVFNVSIPDHGYA
                     PPGTEGLHNRYFSTLTIDVVLTTTIGTYVTGLSAIWDGGWDYQYQY"
     gene            6184..7074
                     /locus_tag="PKM11_04880"
     CDS             6184..7074
                     /locus_tag="PKM11_04880"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47874.1"
                     /translation="MTVVGLTKTYGSRLTARNVHALNGASFELKRGEICGLVGPNGAG
                     KSTLIKLIMGIEPRNEGRIIFGDENIGIIGYVPERPTFFEDLTAFQNLLYIARLDEMP
                     GAEDLCHKALDRFGLGERKDDLVRTFSKGMKQRLAIARALISSPKLLVMDEPFSGLDP
                     TMVMDLRGHLKGLRGTGLTILVSSHELNEIDQVCDSIVFIKDGRMVKKEGYARDDGYV
                     KLQITVLNPSEDVMAAMSTAKIISADGGTIVIELRRSEVPATMKRIVDAGGQLIESKI
                     LQRKAEEMYADVFLRKEAGQ"
     gene            7071..7946
                     /locus_tag="PKM11_04885"
     CDS             7071..7946
                     /locus_tag="PKM11_04885"
                     /inference="COORDINATES: protein motif:HMM:NF024091.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HNX47875.1"
                     /translation="MTEFLEHLRKDVQIYRSDSLYLLFVLIVTVMAFIMSFVSTSSYV
                     SQWPNLLTTEIEMLERQRESLDTYWLTMSNTLLILFVLISSMAMTPEKENGMVRYVLT
                     HRTHGWMMYLSKYLVLACLAIYAVTASSLAYFLVFTAMDLPLLSAGDVFSAMVMPTLT
                     VLAICAIGLMVSALMNKKGAAIALGVVLFLVISMSSTLVTSLAIEAAHDHPDWEPGLD
                     EADYIPGYYKALIRMNPMSLVSGSGMIGEGEGVLIGLGMIAAYVSLGIFIFARERTEF
                     GLLKDLGAKIGGRGR"
     gene            complement(7959..8891)
                     /locus_tag="PKM11_04890"
     CDS             complement(7959..8891)
                     /locus_tag="PKM11_04890"
                     /inference="COORDINATES: protein motif:HMM:NF018024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1028 domain-containing protein"
                     /protein_id="HNX47876.1"
                     /translation="MFVPDHFAKGPFAHTYSIVARDERTGEIGAGVQSHWFSVGTVVP
                     WALAGVGAVVTQSFTNPAFGPEGLRLLSEERSPEEAVGKMVSKDGGRDLRQLAIIDSR
                     GRSFAHTGKKCVAEAGHISGKNFSVQANMMLKDTVWPAMAEAFETSDGPLADRIMASL
                     MAAEKEGGDARGRQSAAMVIVRGKGTGQVWKDRLIDLRVDDHRDPLKELARLLKVHRA
                     YESMDEGDKAMEDGDTDLALSAYSKAQKAFPRNAEMLFWHAVGLANKGRFDESLPLFQ
                     KAFAMNPNWRLMVPRLRPNGMLELSGRQVERLLR"
     gene            complement(8966..10798)
                     /locus_tag="PKM11_04895"
     CDS             complement(8966..10798)
                     /locus_tag="PKM11_04895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47877.1"
                     /translation="MSEDDSKPRPKGPAGFGPGHGPMMAGKPKSFKTAWKKMLAYMRQ
                     YIPALIVASTLVIIGTVFTVIGPDKLSDLADLIATGMFTGTIDLDGVAEIGTFLVIIY
                     LLSAVLTYGQGYIVATIVQRLSKRLRTDISEKINRLPLKYFDKTSYGDVLSRVTNDVD
                     TVGMSMNQSVGMLMSSAALLIGSLVMMLYTDLIMTAAAVGSAVAGFMLMAFIMVKSQK
                     YFERQQKHLGRLNGHVEEMYSGHVIVRAYNGEKAAQKEFDSINDELFDSAFKSLFLSG
                     MMMPLMGFIGNFGYVAVCIVGAVQVLNGTITIGVIVAFMLYVRLFTQPLSQLAQAATS
                     LQSVAAASERVFEFLEEPEMENEDGKKTVLKDVKGDVEFRNVSFGYSPEREVIHNFSY
                     HVRSGQKVAIVGPTGAGKTTIVNLLMRFYEVNSGDILIDGVSTKELTRNNVHGLFCMV
                     LQDTWLFEGTIRENIAYRKEGVTDEMIEEACRAVGIHHFIATLPDGYDTKLDDESKIS
                     MGQRQQMTIARAVVQNAPLLILDEATSSVDTRTEKIIQKAMQDLTVGRTSFIIAHRLS
                     TIKDADTILVMREGSIVESGTHEELLKQGGFYSGLYNSQFENCD"
     gene            complement(10795..12540)
                     /locus_tag="PKM11_04900"
     CDS             complement(10795..12540)
                     /locus_tag="PKM11_04900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47878.1"
                     /translation="MILKHLKAKEWALMVACTGFIVLQVWLDLEIPDYMYQITKLLQT
                     GGTVEQVMAQGWPMLGLALGSLGTALVIGYIAAYVATSLAKRVRAMQFHKVQSFSANE
                     INKFSTASLITRATNDVTQVQMAVAIGLQVIIKAPIMAGWAIIKISGKSWQWTSATAV
                     AIIVMLTMIGILMYFVVPRFKKIQWLTDDVNRNMRENLKGIRVIRAYNAEKYQENKFE
                     KANEELTANNLFTGRAMSLMMPVMMTVIGLLSLSIYWIGAILIDAASGLPAQIALFSD
                     MIVYIAYAMQVVMGFMMLVIVFFILPRAIVSARRIEEIIETEPSIKDGTVPSRPGNGE
                     IEFDKVSFKYPGAADYVLRDISFKADQGETIAFIGSTGSGKSTIVNLLLRSYDVTEGS
                     VKVDGVDVRDYTQEALHQKMGYVPQKAMLFSGTVFSNVAYGDMSSERTEADVRTAVTI
                     AQGAEFVEGMKDGYYSSIAQGGTNVSGGQKQRLSIARAVCRRPEIYIFDDSFSALDYR
                     TDRCLRSALKKETADVTSVIVAQRVGTILDADKIVVLDNGSVVGIGKHHELLDTCPVY
                     REIVESQLTEEDMRR"
     gene            complement(12537..13031)
                     /locus_tag="PKM11_04905"
     CDS             complement(12537..13031)
                     /locus_tag="PKM11_04905"
                     /inference="COORDINATES: protein motif:HMM:NF015513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HNX47879.1"
                     /translation="MMGKPNTYKGNRISPSQLIMLIKLADRPMYGYELLKALREDYKG
                     VWDPQTGAVYPALRRLQEHGLLSVENKDGKDIYRLTPEGEGWLDETLATMSSGILFMS
                     RTMEVMGRAYLERKGEVENFIPLDERSPEERLKHMMVIRDGVQNNLRMLESYISELEK
                     ELKQ"
     gene            13151..13918
                     /locus_tag="PKM11_04910"
     CDS             13151..13918
                     /locus_tag="PKM11_04910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47880.1"
                     /translation="MDLTYEEIPEDLWEDWVWLVSPPGLTRSVEEETQPLLNSPYQLT
                     STYTVNFPKIVLFHMSWSCAAAADGDVSPNDLQVAVHMDTDVALQGLLFLLKNYPLVL
                     RWKLDDDQRASLAPNLWDDLQEPPELLWHVPQELEGRALDLESISIEFFNPFVPALRL
                     AGIPRSVIGVISPVKNMDLAISSLIPGVESDWREAMTMAINELERRGLIEIADEGRMR
                     FTERGRRMAVTEPLSDCLSCRCRIDEVMEYEMGGDED"
     gene            14071..14994
                     /locus_tag="PKM11_04915"
     CDS             14071..14994
                     /locus_tag="PKM11_04915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47881.1"
                     /translation="MKLWDFGRVKDGKVQIGDKIRRRLGLEDGSQVYSTLFRYEQNGS
                     RGHEMVLSTFGPENYRELCNLTFYMIDAPGACSQAAKFLADRNVDILNSVSVSMTCGI
                     SMVWKMLVDLSYYGDSTQLMEDFASLRRTSPAALSKVEGLEINHSHISDRYTKGMTGP
                     TSGRIKVKPLRKVARSPSLISDGNFKIPKDYLDNMEDVKEGTPVMMVGDVDSWVLSMS
                     FLPEDCKLAEISLEIPDKPGAIFKATEALAAQEVNLLAVQSRVVVYGQIMALDLVADL
                     HKAGELDQVVAKVLDSLGGEFKLRSKGPVTF"
     gene            15005..15763
                     /locus_tag="PKM11_04920"
     CDS             15005..15763
                     /locus_tag="PKM11_04920"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR00121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HNX47882.1"
                     /translation="MLIGRKVLVKGEVDSTNNIAKTLAIDGEPEGTVVSALRQTGGKG
                     RTGRHWESPEGGLYLSIVLRPDLPAQDLTLLTVLSCLPVAQAIEEVCKVVPRIKWPND
                     VRIDGKKVAGILTEVCYRGGEPRFMVLGIGINLNTDVSALNAPEAGSLKDICQRGLDP
                     ELFMNVLLFKLDEFYAKFRKGDRDLDLYARYSESLGQDIEVRLGDQKVKGRGMHLDPD
                     GALVFRSEDGMIYRATSVHDVVPLDRGQVRFDSK"
     gene            15803..>16140
                     /locus_tag="PKM11_04925"
     CDS             15803..>16140
                     /locus_tag="PKM11_04925"
                     /inference="COORDINATES: protein motif:HMM:NF013225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="HNX47883.1"
                     /translation="MGEDKVKELRDMKKRSRAGGGAERVEAHRAQGKMTARERVEALL
                     DPGSFSELDTFVSHQAYHFGMEKQKVPGDGVVTGRGTIEGRQVFVYAQDFTVFAGSVG
                     RMHAKKICKV"
     assembly_gap    16141..16240
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <16241..17221
                     /locus_tag="PKM11_04930"
     CDS             <16241..17221
                     /locus_tag="PKM11_04930"
                     /inference="COORDINATES: protein motif:HMM:NF013225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="HNX47884.1"
                     /translation="FMFMVGPDVIKAVQNEMVTFEELGGASVHATRSGSAHFVAEDDL
                     DCVKQVKKLMSYLPSNNLEQPPKKQMGDDPERREDSLDTIIPEDPMKPYDMKEVVRKV
                     VDKGELLEVQEQFARNIITAFARMNGAPVGIVANQPMALAGTLDANSSLKAARFVRFC
                     DSFNIPVVTLVDVPGYMPSVEQENGSLLRDSTKLLYAYAEASVPKITLITRKAIGGAY
                     CVMGSKALRSDVNLAWPTAEISIVGPEGAINIVFKQELIMADDPQEKRDVLISEYRKM
                     YASAFFSAERGYLDDIIEPNNTRMRIIEGLQMLDRKREARPAKKHGNMPL"
     assembly_gap    17377..17476
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <17477..18556
                     /locus_tag="PKM11_04935"
     CDS             <17477..18556
                     /locus_tag="PKM11_04935"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: protein motif:HMM:NF006761.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HNX47885.1"
                     /translation="YTISPVHTIDGYIKFARKLQDMGADTICIKDMAGMLAPMEAYEL
                     VKQLREDIGLPVHLHCHATSGMVMSTYTKAIEAGAEIVDTAISSMSLSTSQPPTEAVV
                     AMLRGTEYDTGLDLKKLTAISEYFESIRKKYQAFESGFTGIDTNVLVYQIPGGMISNL
                     ISQLREAKKEDRLADVYDEVPKVKADLGHVPLVTPTSQIVGTQAVLNVITGERYKMVT
                     NETKNLVRGLYGKTPADIDPAIRKKIIGDERPITVRPADLLEPEFEKLAKEIEEYACK
                     ENMACSEEDVLSYALFPQVALDYFKHRQMMEKGVNYRDLAAIAVLYMRSTEKHVSNND
                     RGNGNVDAWKCAAINEAVGRGGWPL"
     gene            18553..19056
                     /locus_tag="PKM11_04940"
     CDS             18553..19056
                     /locus_tag="PKM11_04940"
                     /inference="COORDINATES: protein motif:HMM:NF012584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47886.1"
                     /translation="MKLRITVNGQEYEVVVEKNGGDYRVAIGDHVFKCIVKDEKVMVN
                     GEVAPIIIEGDLEEGAKVMSDDRTMEVKLHHVREIEHIALEEMEDGGRSESASGAVLS
                     PMPGKIMSVKVKVGDTVAANQVVCVLEAMKMENEVQTEVAGKVKEVKVKAGETVEGGQ
                     PLIVVEP"
     gene            complement(19053..20351)
                     /locus_tag="PKM11_04945"
     CDS             complement(19053..20351)
                     /locus_tag="PKM11_04945"
                     /inference="COORDINATES: protein motif:HMM:NF017044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin family protein"
                     /protein_id="HNX47887.1"
                     /translation="MDRSGKSRRVDQDIKVGSTPGGIKVIVESMPYVHTVALSVAATV
                     GSRDEKVKESGVSHFLEHMLFRGTKTRDYRDINEGIEASGGYLNAYTTHEHTCFYAFT
                     IDESLKTAEDLLSDVFLNPRMDPELVDLERNIVKQEIGMRMNDPAAHLRTKMSESIFR
                     GNPLSRSILGTPESLDGFDSEFLLNYHGTHYHPPHVVICAVGNVDFSRVLEWAGRFDA
                     VGGKAAVKRRRRPEIRTGVNFYEKGSDRAYIGIGVPGYSAAHKMSLAQGMLTMVLCGG
                     TSSRLNHRIREVEGLVYSISMYPLTFPDCGALMTYCSTSMEQVPRLFDTFGQELSRFK
                     KEGLNEGELEKARNGLKGSLLRNACRPDQNMSSHIGQFLERGKVMSIEEQLAEINAVT
                     AEQIAKAAEALLIGSKACVTICSAKDMRAEMTEAAEALDF"
     gene            complement(20392..20580)
                     /locus_tag="PKM11_04950"
     CDS             complement(20392..20580)
                     /locus_tag="PKM11_04950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47888.1"
                     /translation="MRTVRICEKCGHQFPPRIKGWNAVDVRYERCPRCGHENGYESDL
                     YRWLRRRKERGRRKVRKG"
     gene            complement(20577..21158)
                     /locus_tag="PKM11_04955"
     CDS             complement(20577..21158)
                     /locus_tag="PKM11_04955"
                     /inference="COORDINATES: protein motif:HMM:NF017088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47889.1"
                     /translation="MSGLEDIMGKEVISSDAIIIGTVDGVGIDTDNWKVPAIRISVRK
                     GNEAALGLKKKAIGVRKIFVATPQVSSVSDTVTLAVKMDQVKEVVVDEKKVFMTAGDM
                     LNKKVVGQDGKLIGFMDNVYFDTTRSWEIGKLGIKLDKTAKQSLDLQKGLAPSSQISI
                     LSKDVKSVGDMVMLRLDIDSLKTYLSTKPVSKK"
     gene            complement(21336..22907)
                     /locus_tag="PKM11_04960"
     CDS             complement(21336..22907)
                     /locus_tag="PKM11_04960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HNX47890.1"
                     /translation="MSFRNLNTYESMVKAGEESSFHTRYDRAVERFVQSLEVGSTYES
                     LIDGKPVPTGKYFTDTSPIDTELVLGEFSLGGEKEASLALSAARRAFQTWSVMDLDKR
                     LVIFRKAAEIMRRELFEIAAAITIDNGKNRYEAVGEVDEAVDFISFYADRMEARHGFR
                     EDTEPAYADEKPISVMRPYGVWAIVCPFNFPIAISAGMLTAAIITGNTAVLKPSTPAP
                     LAVHMLYDVYERAGVPNGVINLLSGSGSVAGEALVSSDKIDGIAFTGSKEVGYRLLSS
                     PRRYPIPVITELGGKNPAIVTEKADLAKAIAGVAISAFGYSGQKCSACSRVYVHELVY
                     DEFMIYLMKHLARSRVGDPRERATFTGPVIHQKALDDYLGYSHQARIDGVLHVGGEAM
                     KGKLSKGFYATPTLVTGLPEDHFLVRNELFLPILCVQRFTDLKDAVRRANDVDYGLTS
                     GIYSDDEDEVNYFFENIEAGVSYANRARGATTGAMVGAQPFGGWKGSGSTGLGSGTDM
                     YLAQYMRQQSRTVSR"
     gene            23023..25974
                     /gene="acsB"
                     /locus_tag="PKM11_04965"
     CDS             23023..25974
                     /gene="acsB"
                     /locus_tag="PKM11_04965"
                     /EC_number="2.3.1.169"
                     /inference="COORDINATES: protein motif:HMM:NF007078.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit alpha/beta"
                     /protein_id="HNX47891.1"
                     /translation="MSFQGVVDLSPEPYRTNAKEVLDLVRSKRLALLSDVNGMPTDPV
                     AEVRRTLTGPLSAPDLWKVDLGACLDLVDRDLAKKAGLEPMVVRERKVWEQAGMLAPM
                     DAMPSGDAFALLLALREALACSLLRFCLDANTENIEHDVQDSDLKEGVLRGLALDLGK
                     GWYGLGATTVPASKGDAGLRSFRSLRRHLCRKLGTTSAQLPLVLRTTELDIALGEVLL
                     GSPVSLEGLAFDDICQEFLFHTVRDVFGGCLEPEAGIGMEIERRRWLSGLPHRYEPPA
                     PAEASNAAVIGLGFLGASLLSALAITVTKAAISRKGDAPLEYPETAYSLPCIMGWDGE
                     EVASLGTLLTVLERHSSLPSERGLAQALEAGRTAMIAAEALEALRYLDGDPHVGTSAV
                     GFIPDKVLRELGLALVDDTIPGAAVIMGIPLDRRQLVTTVRELQARGMLIMAADEVVK
                     VLQENEVQMGLGMMLYPLGNFTQLVHSLDFVVRAALSFGGLQKGDSERLSAYLAKRPK
                     AFVLHYGPLDASRASLALAALLHHVPIITDQLVEGVPDLLIHKEPASMLQGGLESRDI
                     RTAVTLVDIPVPFGPAFEGETVRRPDTYFEAGGGRTPSFELLKMRPEEQVKDGSIMVI
                     GPDVDRLPEGSQSPLAILVDVFGKRMQEDFESVMERRIHLYLNFAEGVWHTGQRNMNW
                     LRLSKKAFRAGFRLEHLGRILVTKLKEEFGNIVSRVQVTIVTDENELRKRMPEALAAY
                     QIREERMAGLTDESVDTYYSCLMCQSFAPDHVCIITPERLGLCGAINWLDAKTGKEIV
                     PSGPNQPIAKGEEDDAGKGSWKGVNEAVTALTRGKITRFCAYSMMEDPMTSCGCFEVI
                     VAMSPDMQSVVVVNREFPDMTPVGMKFSTLAGSIGGGKQTPGFIGIGRKYLVSKKFIS
                     ADGGFLRISWMPSSLKESMREELINRARELGAPDFLDKVADETVVTDAEGLFQWMVKV
                     GHPALGLPPLL"
     gene            25984..26931
                     /locus_tag="PKM11_04970"
     CDS             25984..26931
                     /locus_tag="PKM11_04970"
                     /inference="COORDINATES: protein motif:HMM:NF003376.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HNX47892.1"
                     /translation="MEVPVPREKWAGSIGEMELGASLEKGGSRSSLRLGGNKGLPFLS
                     FEDPTSRNVALAGFVADSLEDVPLPVKRAFGNAVNDPARWAAAWKEKGADLICLHLTS
                     TNPEEKDVSPEEAAATVMAVMKAVELPLIIYGSGHPEKDAKVLEKVGEAAKGERLLLG
                     QAEEGGYKSVAAASMANGHAVIGFSNLDINLAKQIVILLTDYGVGRGDVIIDPLMAAL
                     GMGLEYSYSVNERIRISALSGDAMLQVPMICDCVSAWKAREASDDIPQAGDTLERGIW
                     WESTTALAALLSGADILVLGHPGSLQIAKDALKGFRGEA"
     gene            26931..28250
                     /gene="acsC"
                     /locus_tag="PKM11_04975"
     CDS             26931..28250
                     /gene="acsC"
                     /locus_tag="PKM11_04975"
                     /inference="COORDINATES: protein motif:HMM:NF003195.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HNX47893.1"
                     /translation="MATAIEIFKHLPKKNCGDCKFPTCLAFAMQLANNKAKLDDCPHL
                     SEAGRNALASSSAPPIRLIKVGSGKNAVDMGDETELYRHDKRFFHPVAFALRIADDLG
                     EDDLYKRLSYVRSLRFERVGQVLKMDLLELECRSGDADRFAAFVKKVASESELPLVLR
                     TKDAAAMSAAANAIKEKRPLLHGADASNLKEMCVVAKSCACPLTVGADDLNGLADMVE
                     AVRKEGVEDMVLDPRPSSLKELLERCTIIRRSAIRKTFRGLGYPIYLSIPAGRDGMLM
                     ASTAVMKYGSLLSFEELPASNALPLMVLRQNIYTDPQVPIQVKPDLYPVNNPGPDAPL
                     LFTTNFSLTFFTVMSDLEKSKVPVWLQVVDTEGLSVLTAYSAGKLTSESVKNALQSTG
                     ALERSKKGTLVIPGMVARMAVKLNEATGLQIIVGPKESSGLPKFLRS"
     gene            28334..>28611
                     /locus_tag="PKM11_04980"
     CDS             28334..>28611
                     /locus_tag="PKM11_04980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47894.1"
                     /translation="MQQGPYDPNQPGQQPYQGQQQGPQQWPQQNPPNNYQQPPQQQPQ
                     YQQQYQPQQYQPYPPQQYYQPPKKKRNMKLIVAVVAVVAILLIASMAVL"
BASE COUNT         5817 a         8373 c         8403 g         5718 t
ORIGIN      
        1 agtgcggggg aagggattcg aacccttgaa ccactaagga cagaatctta agtcctgcgc
       61 cgttggccaa gcttggctac ccccgcgcac ttcggccatg gaagattcga cataataaat
      121 ttgccgaagg gcggcggacg ccatcgcgtc cgttccttac ttgatgaacg tgcctcgttt
      181 caggtccgag aacgcatggt ccagctcctc tcgggtgttc atcacgatag gaccgcccca
      241 ggcgatcggc tccttcagcg gtttcgcgga gccgaacatg aacttggtcg gcctccggcc
      301 gacggtgaac ctgaagctgt cgccttcgcc cagtaccgcc acgcttccgg ccggcaccgt
      361 cctggcgtcc ttgtccccga ccagcatctc cccctcgtaa acgaatacga aggcgttccg
      421 ctcggccggc acctcatgct ccaggaccgt cctggaattc agcgttatgt ccagatattt
      481 tacgtccacg accaggtcct tgaccggacc gaccagaccc tgcgactcgc cggcgatgac
      541 cttgatcgag gaaccgttgc cgaggtcgaa caccgggaag tcctccttct tgaggtcccg
      601 gtaacgcgga ggcatcatct tgttggcctt cggcagattc acccacaact gaaaaccttg
      661 catccagcct ttcgctcttt gcggcatctc ttcatgcaga atgccgctcc cggcggtcat
      721 ccactgcaca tcacccggac ctatgacccc gtggttcccc aaagaatcct tatgtgcgac
      781 gttaccatcg agcatgtagg tgaccgtctc gatgccccgg tgagggtgca tcggaaaacc
      841 ggccaggtaa tcctccggcc ggtcggaacc gaaatggtcc aacatcaaga acggatcgag
      901 caacgccgcc tcgtcccggc tgaacattct ggtgagcttg acgccggccc cgtcatgggt
      961 ggactggcca tgaatgagct tggccacctc tcttatggat gacataggtc ccaatatcaa
     1021 ttgaggtgag atatgaataa atcgattgtt aacgataacc tatacgaaat atgcctaagg
     1081 agaaacgcaa gataatctgg cactgcgcca acggacacga cttcgaggtg gaggatgagc
     1141 ttcaacggtc catatgcccg gtgtgcggcg gtaatgacgt tgaacgagcg tcgaaggaca
     1201 aggaaaagca gcgccctccc cgtggctcgc tgagatcatg gttctggcgg tgaacgatga
     1261 acacgaaagg cgatcgcaag gaacgtgaat tcttatggtt cccttcagtt gaggactggg
     1321 aggagtggct cgccaagaac catgaccgat cgtccggtat ccgcatcaga ttcttcaaga
     1381 aggcctccgg aaaggcaagt gtcgaccgcc aggaagcgct cgaggtagcc ctgaggttcg
     1441 gatggatcga cagcgtcctg aacaactatg accaggatag ctaccttcaa agattttccc
     1501 cgcggaagaa ggacagccat tggtcccgtg tgaatctgga gacagcagaa aagctgatgg
     1561 ccgagggcaa aatgaccgag gccgggctta gagcgcttgg tgacctgaag aaaagatacg
     1621 agtccctgaa ggaagaggat tccatcgacc ttgacctgaa tggccttttc agggatgatc
     1681 cggaaaccct agcggccttt aacgcactac cgccgtcgca ccgcaagacc tacggaaggt
     1741 acatcctctc ggcgaagctc cccgaaacgc gtgagaggag gatgaagcga gtgacgccaa
     1801 tgataagaga gcgccgaccg ccgatcttgt aaggggaagt ggctcacatc accttgcagg
     1861 agtcgccgtg gcaggcgaag agtatcggac ccagtttctc atcgagaatg tcctccaacg
     1921 taggcttgcc gatctcggcc agttcgtaat gcacgcgcac gatcggcttg ttgacgttca
     1981 tcacccggcg gagatcgacc ggcgttccgg cgacgaccac gtcgcagtcg gccttgttta
     2041 tggtctcctc catgtccttg atctgctcgt cggtgtagcc catggccggc aggatcggac
     2101 cgaggtgacg gtacttttcg taaagctcct tgatcgagcc gaccgcgtat ggtcgcgggt
     2161 ccacgatatc cagggcgccg ttgtcctccg cggctatggt tcccgctccg aaggccatct
     2221 ccccatgagt taacgtagga ccgtcctcca ccaccagaac gcgcttcccc ttgatcatgg
     2281 acgggtcgtc gaccttgatg ggcgaggcgg cctcgatgac gatggatttg ggattgtact
     2341 ttagaatgtt ctccttaacc ttcaggatgt tgcggcggtc ggcggtctgc accttgttta
     2401 tgataacgac atcggccaga cgcagattca cctcgcccgg gtgataggat atctcgtgcc
     2461 cggcgcggtg ggggtcggcg atgacgatat gtaaattgct ttcaaagaac ggcaggtcgt
     2521 tattgccgcc gtcccagacg atgacgtcag cctccttctc cgcctccctc aggatgcgct
     2581 cgtaatcgac gccggcgtag acgacgatgc cgttctcgat cagcggctcg tactcctccc
     2641 gctcctcgat ggtgcaatcg tgcttgtcca gatcggcgta ctcgccgaaa cgctgcaccg
     2701 cctgcttggt cagatcacca tagggcatag gatgacgtac ggcgaccacc ttcagaccgc
     2761 gatcgtgcag gatgcggcag agcttcctgg tggtctgtga tttgccggcg ccggtgcgca
     2821 ccgcgcagac cgagatgacc ggttggtttc ctctgagcgt gatagcggag ttgcccatga
     2881 ggcggaagtc cgcaccaagc gacaggaccc aggatgcctt gtgcatcagc tccacgtgcg
     2941 agatgtcgct atacgcgaag atcacctgat cgaccttgtt cttgcggata atcgacggaa
     3001 ggtcatcctc ggccaggatc ggaattcctg tcgggtacag atgacctgcc aatgaagctg
     3061 gatagcacct tccctcgatg ttcggtatct gagcggcggt gaaggccacc acgtggtact
     3121 tctcgttgtt ccggaagtaa gtgttgaagt tgtgaaaatc gcgccccgcg gcgcccatga
     3181 tgacgatctt gctcttcttc atgtcccgac cttctaccgc aatcgaggcc gatgattata
     3241 caattttctg aataggcatc gattttttta ttataatata gataatattt tttctataaa
     3301 gaacattaga aataaataat ggtccgattt ttagatctgc taaaaactgc caattactgc
     3361 taaattagct gatttcaacc attcggaaat gcaacgttaa gaccgatcat cgaactgcta
     3421 attactgcta attactgcta aattagcaga tattatatta accagcataa acatgctatt
     3481 gattgagaac aatgaagatc cctgagagac cgaggtcctt gcaagatata tttaaagata
     3541 agattataaa aaatccggtc ttcacggaag atagaactgt ttccgaccga gtgaaacaat
     3601 tcaatgagga ttatcttcat tgggacgagg tcagacgtaa agatatgcca caagatccag
     3661 aggtcgtctg ggcattgatg aagatgtcgc gacaggggca atcgcggcat gtcgcctttt
     3721 taaacacctc gttgacctac aatacgacca gtcgatcaca gaggatcatg catatgctgg
     3781 ataccaccgc ctctgggttg ttggttttgg aagaaccgct gaaagattcg gagatgaaaa
     3841 gatatgtgat tagttcgctc atggaagagg ccatcgcatc aagccagttg gagggggctg
     3901 tcaccacnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnngcc actaagttca
     4021 acgtggttca tcagaccgcg cgtaccgacc tcttatccct ctctgaaaga gggttcatcg
     4081 aaagaaggaa ggtgggcaac aaattattct tcgtgtatac tggatcatcg agtttgaatg
     4141 accgcaccaa agatgcgctc atcgacaaca ataggggatg aggcggtatt gatgatgagt
     4201 atcatcccat attcccgtgg acgcctatcc tctggtattt acttgacaac gacgaacatg
     4261 gccccgacca caccttctga ataatgcgtt ggcctgggtc ctagtatgtc actgacccta
     4321 tcgactaggc ttaggaaagt attgagtatt caccctacga ttcatcccgg atggtctacc
     4381 gcataccctc ggtcaaggta ctagaggact ccatcagaaa ggtgatccgg gagcagcaga
     4441 gcattccctc ccagcgtctt ttcaccgaac tggtgctgga ggaccttcat aagaagaacc
     4501 ccgagtacaa ggtgggcgag gttcgtttaa ggcgtatggc cctgcaccgc aacctggcca
     4561 aggtcaccat ctcctatcgc gagacgaagg accccagcca taaaggccgt tgcccggtgt
     4621 gctgttcccc catcgaggaa ctgcacaact ttacattgga cgagaagaag gtcgagctgg
     4681 ggttcaagtg caccaagtgc ccgtactgga ccggcccgcg caggcgtgtt ccagttcgat
     4741 acaacttcac catgttcggg gcgatagtcc cgccgagcaa gaagaaaggc aagttcgccc
     4801 agtggaagtt cgcctaggca ccgtatttat tctgcgatat cgttccctgt cgcatgtgcc
     4861 gctcgacggt gtacatgtcc accaaggaag gcgttctgga actggtcaag aacgcggtcc
     4921 ggttgaacct ggatgacgaa gttctagtta tcatcgacga tgtcggggaa cgattggagc
     4981 tgcagaacgt tcgaataaaa gaggtcaacc tcatcagcaa caacatcgtg ctggcgaagg
     5041 acccctccga gaattgactc cctatccagg ccgtgccctc tgaagcatgg tccgttccaa
     5101 tatgatcaac gtgagagcgg gcgaaacctt tactatcttc atagcccaac acctccccgg
     5161 ggaatgacgt tccgagggaa cgtctggatg gtcggggata gacaatgagg atcaagagac
     5221 agtatatggc cgtcatcttg gccgtcatgc tcgtgatcag ctctctggcg gcgttcgtgg
     5281 cctacgaatc ggttcagcgc aacagactgg gatacatagg catagaggtg gataaggagg
     5341 tcttcacctc ggaggaggat gtaaccttcc gactggtatc cctttccagg aacgccgagt
     5401 tcaacatcac cgaccgctgg aacgatgatg tggacgatga tttttacaga ggattggacc
     5461 tggtgagggt gccggacatc atggacgctg agaccttcct cgacgacctg tcgtcgctcg
     5521 attatcttcg caaccataac acctatgttc ccttaggccg ggcgttcttc gaccacttcg
     5581 acagccagga cgattccctc caggtcacct ggaacggtac cgtggtcaag gagtactggg
     5641 atggtaatgg gtcgttcctc agatacagtc cggcggtcag cggcttttat gtcatcgttc
     5701 ccaggaactc ctggagcgca gatcataagg tctctttcct tgtcaatgaa aggtccgtgt
     5761 tctactatga ctccctggac gttggaatga aggtcacgaa ccatatcgag gaggatgtga
     5821 ccgtggaact tacgctccgt gcccctccct ggacgataga taacgtcacc tgcgatttgg
     5881 acctcgtcct gtactaccag ggtagcatct tcgagcccgc ggaagatgaa gatgcccatc
     5941 actatgagga gaaaagcatc gtccttaacc ctgggcagga ccgggtcagg accttggtct
     6001 tcaatgtcag cataccggac cacggttacg cgccgccggg gactgagggc ctccataaca
     6061 ggtacttctc cacattgacc atcgatgtgg tcctgaccac caccatcggc acctatgtca
     6121 ccggtcttag cgccatctgg gacggggggt gggactatca ataccagtac tgatgatgcc
     6181 ttgatgaccg tggtcggcct taccaagacc tacgggagca gactgaccgc tcggaacgtt
     6241 cacgccctca acggagcctc cttcgaactg aagagggggg agatctgcgg gctggtgggt
     6301 ccgaacgggg cgggtaagag cacgctcatc aaactgatca tgggcatcga gcccaggaac
     6361 gagggtagaa taatctttgg ggacgagaac atcggcatca tcggctatgt gcccgaacgg
     6421 ccgacgttct tcgaggacct cacggccttc cagaacctgc tctacatcgc caggctcgat
     6481 gagatgcccg gtgcggagga cctctgccat aaggccctgg atagattcgg tctgggcgaa
     6541 aggaaggacg acctggtgag gacattctcc aaagggatga agcagcgcct ggcgatagcc
     6601 agggcactga tctcctcgcc caagctgctc gtcatggacg aaccgttctc cggcctggac
     6661 cccaccatgg tcatggatct ccgaggccat ctcaaggggc taaggggcac cgggctcacc
     6721 atcctggtat cctcgcatga gctgaacgag atcgaccagg tgtgcgattc catcgtgttc
     6781 atcaaagatg gcaggatggt caagaaggaa ggttacgcga gggacgacgg ttacgtgaag
     6841 ctgcagataa ccgtgctcaa cccatcggag gacgtcatgg cagccatgtc cacggccaag
     6901 atcatctccg ctgacggagg caccatcgtg atcgagctga gaaggtcgga ggttccagcg
     6961 acgatgaaga ggatcgtgga cgcgggcgga cagctgatag agagcaagat actgcaacgt
     7021 aaggccgagg aaatgtacgc cgatgtgttc ctgaggaagg aggcggggca atgacagagt
     7081 tcctggaaca tctgcggaag gacgtgcaga tctaccgatc cgactcgctg tatctcctgt
     7141 tcgtactgat cgtcacggtc atggccttca tcatgtcctt cgtgtccacc agcagctatg
     7201 tgtcccagtg gcccaatctg ctcaccacgg agatcgagat gctggaaagg cagagggaga
     7261 gcctggacac ctattggcta actatgagca acaccctcct catcctgttc gttcttatct
     7321 cctccatggc catgaccccg gagaaggaga acggcatggt tcgctatgtc ctgacccacc
     7381 ggacgcatgg ctggatgatg tatcttagca agtatctcgt cctagcctgc ctggccatct
     7441 acgccgtgac ggcgtcctcc ctcgcctact tcctggtgtt cacggccatg gacctgccat
     7501 tgttgagcgc tggggacgtg ttctcggcca tggtcatgcc aacgctcacg gttctggcca
     7561 tctgtgcgat cgggctgatg gtctccgccc tcatgaacaa gaagggggct gccatagccc
     7621 taggcgtggt gctgttcctg gtcatatcca tgagctccac cttggtaacc tccctggcca
     7681 tcgaggccgc tcacgaccat ccggactggg aacccggtct cgatgaagca gactacattc
     7741 ctggatacta caaggcgctc atcaggatga accccatgtc cctcgtatcc ggatcgggga
     7801 tgataggtga gggggagggc gtgctcatag gtctgggaat gatcgctgcc tacgtttcct
     7861 tagggatatt catctttgcc agggagcgta cggagttcgg tctgctaaag gacctgggag
     7921 cgaagatcgg aggaaggggt cgctagcgaa aagatctctc acctcaacag gcgttcgacc
     7981 tgtcggccgc tcagttcgag catgccgttc ggcctcagcc ggggaaccat caacctccag
     8041 ttcgggttca tggcgaacgc cttctggaac agcggcaagg attcgtcgaa acgacccttg
     8101 ttcgccaggc cgaccgcgtg ccagaacaac atctccgcgt ttctgggaaa agccttctga
     8161 gctttggagt aggcgctcag cgcaagatcg gtgtccccgt cctccatcgc cttatcgccc
     8221 tcatccatgc tctcgtaggc ccggtgcacc ttaagcagcc gtgccagttc cttcagcgga
     8281 tcgcggtggt cgtcgacgcg cagatcgatg agccggtcct tccacacctg tcctgtgccc
     8341 ttcccgcgca cgatgaccat ggccgcgctc tgcctccccc gggcgtcgcc cccttccttc
     8401 tccgccgcca tgagcgaggc catgatcctg tcggccagtg gaccgtccga cgtttcgaaa
     8461 gcttcggcca ttgccggcca gacagtgtcc ttgagcatca tgttcgcctg cacggagaag
     8521 ttctttccgc tgatatgccc ggcctcggcc acgcactttt ttccagtatg ggcgaacgaa
     8581 cggccgcggg aatcgatgat ggccagctgc cggaggtccc gtcctccgtc cttggagacc
     8641 atcttcccca ccgcctcctc gggggacctc tcttcggaaa gcaacctcaa tccctccggc
     8701 ccgaaggcgg gattggtgaa ggactgcgtg accacggcgc ctacccctgc cagggcccag
     8761 ggcaccaccg tgccgacgga gaaccagtgt gattggacgc cggccccgat ctcccctgtc
     8821 ctttcatccc tggccacgat ggaataggtg tgggcgaacg gtcctttcgc gaaatgatct
     8881 ggaacgaaca tggtggctac ctatcgctcg atggggatga ggaaaaataa aggttggtaa
     8941 gaggtttgaa aaatgtttcg aaggcctagt cgcagttctc gaactggctg ttgtacagtc
     9001 cgctgtagaa gccaccctgc ttcagcagct cctcgtgcgt gccgctctcg acgatgctgc
     9061 cttccctcat caccagtatc gtgtcggcgt ccttgatggt ggacagccga tgcgctatga
     9121 tgaaggaggt gcgtccgacc gtcaggtcct gcatggcctt ctggatgatc ttctccgtcc
     9181 tggtatcgac ggaactggtc gcctcgtcca atatcagcag gggagcgttc tgcaccaccg
     9241 cccgggcgat agtcatctgc tgcctctgcc ccatggatat cttcgactcg tcgtccagct
     9301 tggtgtcgta accgtcaggg agcgtggcga tgaagtggtg tatgcccacg gccctacacg
     9361 cttcctcgat catctcgtcg gtcacgcctt ccttgcggta ggcgatgttc tcccgtatcg
     9421 tcccttcgaa cagccaggta tcctgcagaa ccatgcagaa caggccgtgc acattgttcc
     9481 tggtgagctc cttggtggag acaccgtcga tcaggatgtc cccggagttc acctcgtaga
     9541 agcgcatcag caggttcact atggtcgtct ttccggcgcc ggtagggccg actatcgcca
     9601 ccttctgccc ggaccggacg tggtaggaga agttgtggat gacctcgcgt tccggagagt
     9661 aaccgaagga tacgttgcgg aactccacgt ccccctttac gtccttgagg accgtcttct
     9721 tgccgtcctc gttctccatc tccggttcct ccaggaactc gaagacgcgc tccgaggcgg
     9781 cggccacgga ttgcaggctg gtcgccgcct gggccagctg cgacagcggc tgggtgaaga
     9841 gtcgtacata cagcatgaag gccacgatga ccccgatggt tatggtgccg ttcagcacct
     9901 ggaccgcgcc gactatgcat acggcgacat aaccgaagtt gccgatgaag cccatcaacg
     9961 gcatcatcat gcccgatagg aacagagact tgaaggcgct gtcgaacagc tcgtcgttga
    10021 tggagtcgaa ctccttctgc gccgccttct caccattgta ggccctgacg ataacgtgac
    10081 cggagtacat ctcctccaca tgaccgttca aacgtcccag gtgcttctgc tggcgttcga
    10141 agtacttctg cgacttgacc atgatgaagg ccatgagcat gaagccggcc acggcggaac
    10201 cgaccgcggc cgccgtcatg atcagatcgg tgtagagcat catgaccagc gagccgatga
    10261 gcagcgccgc ggagctcatc agcatgccca cgctctggtt catagacatt ccgacggtgt
    10321 ccacgtcgtt ggtgacccgg ctcagcacgt cgccgtagct ggtcttgtcg aagtacttca
    10381 gaggcaggcg gtttatcttt tcggagatgt ccgtgcgcaa ccgcttcgaa agcctctgca
    10441 ctatggtggc gacgatgtaa ccctggccat acgtcagcac tgccgatagc aggtagatga
    10501 tcaccaggaa cgttcctatc tcggccacgc cgtccaggtc tatcgttcca gtgaacatcc
    10561 cggtggcgat gaggtcggcg agatcgctga gcttgtccgg acctatgacc gtgaacaccg
    10621 ttccgattat gaccagtgtg gacgccacga tcagcgccgg tatgtactgg cgcatgtagg
    10681 ccagcatctt cttccaggcc gtcttgaagc tcttgggctt gccggccatc atggggccgt
    10741 gcccgggacc gaacccggcg ggacctttcg gtcttggctt gctatcgtcc tcgctcatcg
    10801 tctcatgtcc tcctcggtta gttgagactc aactatctcc cggtacactg gacaggtgtc
    10861 caggagctcg tggtgctttc ctatgcccac cactgagccg ttgtccagca ccactatctt
    10921 gtcggcgtcc agtatggtcc cgaccctctg cgccacgatg acactggtga cgtcggccgt
    10981 ctccttcttc agggcgctcc tgagacagcg atcggtacgg taatccaggg cggagaacga
    11041 gtcgtcgaag atgtatatct ccggccgacg gcacaccgcc ctggcgatgg aaagacgctg
    11101 cttctgcccg ccggacacgt tcgtgcctcc ctgggcgatg gaagagtaat aaccgtcttt
    11161 catgccctcc acgaactccg cgccctgggc gatggtcacg gcggtgcgaa cgtcagcttc
    11221 cgtgcgctcc gatgacatgt ccccgtaggc cacgttggag aacaccgtcc ccgagaagag
    11281 catggccttc tgcggcacgt accccatctt ctggtgcagc gcctcctggg tgtaatctcg
    11341 cacgtccacg ccgtccacct ttacgcttcc ctcggttacg tcgtaagaac gcagtaaaag
    11401 gttcactatg gtgctcttac cgctgccagt ggaaccgatg aaggcgatcg tctcaccttg
    11461 gtcggccttg aagcttatgt ccctcaggac gtaatccgcg gcgccgggat acttgaagct
    11521 gaccttatcg aactctatct ccccgttccc cggacgggag ggtaccgtcc cgtccttgat
    11581 ggacggctcg gtctcgatga tctcttcgat gcgccgggcg gagactatgg cgcggggcag
    11641 gatgaagaac acgatgacca gcatcatgaa gcccatgacc acctgcatgg cgtaggcgat
    11701 gtacacgatc atgtccgaga agagcgctat ctgggccggc agcccggaag cggcgtcgat
    11761 cagtatcgca cctatccagt atatcgatag tgacagcagc ccgatcacgg tcatcatcac
    11821 cggcatcatc agcgacatgg cgcggccggt gaacaggttg ttggcggtga gctcctcgtt
    11881 ggccttctcg aacttgttct cctggtactt ctcggcgttg tacgctcgta tgacccggat
    11941 acccttcagg ttctcccgca tgtttctgtt gacgtcatct gtcagccact ggatcttctt
    12001 gaaccggggg actacgaaat acatcagtat tccgatcatg gtgagcatga cgatgatcgc
    12061 gaccgcagta gcggaggtcc actgccagct cttgccggat atcttgatga tcgcccagcc
    12121 ggccattatg ggggccttga tgatgacctg cagcccgatg gccacggcca tctgcacctg
    12181 ggtcacgtcg ttcgtggctc gggtgatcaa actggccgtg gagaacttgt tgatctcgtt
    12241 ggccgagaac gattgcacct tatggaactg catggcccgg acgcgcttgg ccaacgacgt
    12301 ggccacgtac gccgctatgt aaccgatcac cagcgccgta cccagactac cgagcgccag
    12361 accgagcatc ggccatccct gggccatgac ctgctccacc gtcccgccgg tctgcagcag
    12421 tttggtgatc tggtacatgt aatcagggat ctccaggtcc agccacactt gcaggacgat
    12481 gaagccggtg caggccacca tcaacgccca ttccttggcc ttgagatgtt tgagtatcat
    12541 tgtttcagct ccttctccag ttcagaaatg taagattcga gcatgcggag gttgttctgc
    12601 actccgtccc ggatgaccat catgtgcttg agccgctcct cgggggacct ctcgtccaag
    12661 gggatgaagt tctccacctc ccccttacgt tccaggtacg ctcttcccat aacttccatg
    12721 gtccggctca tgaacagtat tcccgaggac atggtggcta gcgtctcatc cagccatccc
    12781 tcgccttccg gggtgaggcg atatatgtcc ttgccatcct tgttctccac tgacagaagc
    12841 ccgtgctcct gcaggcgacg gagagcggga tacaccgcac cggtctgcgg gtcccatacc
    12901 cccttatagt cctctcgcag cgccttcagc agttcgtagc cgtacatggg ccggtccgcc
    12961 agcttgatca gcatgatcaa ttgcgacggg ctgatccggt tgcccttgta cgtgttcggt
    13021 ttccccatca tgatagtgaa cctcttaagt agatctccac taggtagcgc ggtactacgc
    13081 aacccctatt tcaagatgtc gggcggtacc gcgggatgag tttaaatggc cggagccttt
    13141 cggtcagggc atggacctga cctacgagga gataccggag gacctgtggg aggactgggt
    13201 ctggctggtg tcgcctccgg ggctcactcg tagcgtggag gaggagacgc agccgctgct
    13261 caacagcccc tatcagctga cgtccaccta caccgtgaat tttccgaaga tagttctctt
    13321 tcacatgtcc tggagctgcg ccgccgcagc tgatggtgac gtgagcccca acgacctgca
    13381 ggtcgcggtg cacatggaca ccgacgtagc gctacagggc ctgctattcc ttctgaagaa
    13441 ctacccgctg gtgctccgct ggaagctgga cgacgatcag cgcgcctcgc tagcccccaa
    13501 tctctgggac gacctgcagg aaccgccgga gctgctctgg catgtgccgc aggagctgga
    13561 aggccgagcg ctggacctgg agagcatatc catcgagttc ttcaatccgt tcgtgcccgc
    13621 tttgcgtctg gccggtatcc ctcgctcggt gatcggggtc atctccccgg taaaaaacat
    13681 ggacctcgcc atatcctcgc tcatccctgg cgtggagagc gattggcggg aagcgatgac
    13741 catggccatc aacgaactgg agcggcgtgg ccttatcgag atcgccgacg agggtcggat
    13801 gcgtttcacc gaaagaggaa ggcgaatggc ggtcaccgag ccgctctccg actgtttgag
    13861 ctgtcgatgc cgcatcgacg aggtcatgga atacgagatg ggcggggacg aggactgagc
    13921 ggcgttctga tgccgttctc gccgttcgca tgacattgtg ccaatggaac ctgccgattt
    13981 gcgcccgttc gttggaataa tttgaatcct gggaagattc gcatgacaag ctttatcagg
    14041 gaatagaata tttggcggtt gggtcagcag atgaagctct gggatttcgg cagggttaag
    14101 gacggcaagg tgcagatagg cgacaagatc cgcaggcgat tgggcctgga ggacggaagc
    14161 caggtctatt ccaccctctt ccgctatgag cagaacggct cccgcgggca cgagatggtg
    14221 ctctccacct tcggaccgga gaactaccgc gagctctgca atctcacctt ttacatgatc
    14281 gacgctcctg gcgcctgctc tcaggccgcc aagttcctgg ccgaccgcaa cgtggacatc
    14341 ctgaactcgg tttcggtcag catgacctgc ggaatctcca tggtctggaa gatgctggtg
    14401 gacctctcgt actacggcga ctccacccag ctcatggagg acttcgcctc tttgcggaga
    14461 accagcccgg ccgccctgtc caaggtcgag gggctggaga tcaatcactc tcacatcagc
    14521 gaccgctaca ccaagggcat gaccggcccg acctctggac ggatcaaggt caagccgctg
    14581 cgcaaggtgg cccgctcccc ctcgctcatc agtgatggga acttcaagat ccccaaggac
    14641 tatctggaca acatggagga cgtaaaggag ggtaccccgg tcatgatggt cggggacgtg
    14701 gactcctggg tgctgtccat gtccttcctg cccgaggact gcaagctagc ggagatatcc
    14761 ctcgagatac cggacaagcc cggagcgatc ttcaaggcca cggaggccct ggccgcccag
    14821 gaggtaaacc tactggcggt ccagtcccgc gtcgtggtct acggccagat aatggccctg
    14881 gacctggtcg ccgacctgca caaggcgggc gaactggacc aggtggtcgc caaggtcctg
    14941 gactccctgg gcggggagtt caagctccgc agcaaggggc cggtgacctt ctgaggtctg
    15001 tcagatgctc ataggccgca aggtgctggt caagggcgag gtggattcca ccaacaacat
    15061 cgccaagacg ctggccatcg acggagagcc ggaaggcacc gtcgtttccg ctctgagaca
    15121 gaccggaggc aagggccgca ccggccgtca ctgggagtcc ccggaaggcg gactttacct
    15181 atctatagtc ctaaggccgg acctgccggc ccaggacctg acgttgttga ccgttctctc
    15241 ctgcctgccg gtcgcccagg ccatagagga ggtgtgcaag gtcgtacccc gtataaagtg
    15301 gccgaacgac gtgcgcatcg acggcaagaa ggtcgctggc atccttaccg aggtctgcta
    15361 ccgcggagga gagccgcgat tcatggtcct gggcatcggg atcaacctca atacggacgt
    15421 ttcagcgctc aacgccccgg aagcgggaag cctgaaggac atctgccaga gggggctgga
    15481 ccctgagctt ttcatgaacg tcctgctatt caagctggac gagttctacg ccaagttcag
    15541 gaaaggggac cgggacctgg acctgtacgc cagatactcc gagtccctgg gccaggacat
    15601 cgaggtgcgg ctgggcgacc agaaggtcaa gggccggggg atgcacctgg acccggacgg
    15661 ggcgctggtg ttccgttcgg aggacgggat gatatatcgc gccacgtccg tgcacgacgt
    15721 ggtgcccttg gaccgcggtc aggtgaggtt cgatagcaag taacgttcat taatcatgaa
    15781 tacgcataat gaggggaaca acatgggcga ggacaaggtc aaggagcttc gggacatgaa
    15841 gaagaggtcc cgggccggtg gaggagcgga gagggtagag gcgcaccgtg cgcagggcaa
    15901 gatgaccgcc cgcgaacgcg tggaggctct gctcgatccg ggttcgttct ccgagctgga
    15961 caccttcgtc tcgcatcaag cttaccattt cggaatggag aagcagaagg tccccgggga
    16021 cggtgtggtc accggacgcg gaaccatcga gggaaggcag gtgttcgtct acgcccagga
    16081 cttcaccgtc ttcgccggtt ccgtcggccg catgcacgcc aagaagatct gcaaggtcat
    16141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ttcatgttca tggtcgggcc
    16261 ggacgtgata aaggccgtgc agaacgagat ggtcaccttc gaggagctcg gcggtgctag
    16321 cgtccacgcc acccgctccg gttcggcgca cttcgtggcc gaggacgacc tggactgcgt
    16381 aaagcaggtc aagaagctga tgtcctatct gccgagcaac aacctggagc agccgccgaa
    16441 gaagcagatg ggcgatgatc cggaacgccg cgaggattcc ctggacacca tcataccgga
    16501 ggaccccatg aagccctacg acatgaagga ggtcgtccgg aaggtcgtgg acaagggaga
    16561 gttgttagag gtgcaggagc agttcgcccg caacatcata accgccttcg ctcgaatgaa
    16621 cggcgctccg gtcggcatcg tggccaacca gcctatggct ttggctggaa ctttggatgc
    16681 caactcctcg ctgaaggccg cccgcttcgt gcgcttctgc gattcgttca acattcccgt
    16741 ggtcaccctg gtagacgttc caggctacat gcctagcgtg gagcaggaga acggttccct
    16801 gctgagggac tcgacgaagc tcctctacgc ttacgccgag gcgagcgttc cgaagatcac
    16861 cctcatcacc cggaaggcca tcggcggggc gtactgcgtc atgggctcca aggccttgcg
    16921 ttccgacgtt aacttggcct ggccgacggc ggagatctcc atcgtcggac cggagggagc
    16981 gatcaacatc gtgttcaagc aggagctcat catggccgac gacccccagg agaagaggga
    17041 cgtgctcatc tccgagtacc gcaagatgta cgcctcggcg ttcttctcgg cggagcgcgg
    17101 ctatctggac gatatcatcg agccgaacaa cactcgcatg cgaatcatcg aaggattgca
    17161 gatgctggac cgcaagcgcg aggcccgccc ggccaagaag catggcaaca tgccgctgtg
    17221 aggtgttcga atgaagatca agataatgga caccgtgctg agggacgcgc accagtcgtt
    17281 actggctacg cgcatgcgca ccgatgacat gctaccggcg gcggcgatgc tggatgagat
    17341 cggctactgg tcggtggaga tgtggggcgg ggcgacnnnn nnnnnnnnnn nnnnnnnnnn
    17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17461 nnnnnnnnnn nnnnnntaca ccatctcccc ggtgcatacc atagacgggt acatcaagtt
    17521 cgcccgcaag ctgcaggaca tgggtgccga cacgatctgc atcaaggaca tggccggcat
    17581 gctggcgccg atggaggcct acgagctggt caagcagctg agggaggata tcggactgcc
    17641 ggtgcacctg cactgccacg ccacctccgg catggtcatg tccacgtaca ccaaggccat
    17701 agaggccggg gcggagatcg tcgatacggc catctccagc atgtccctga gcacctcaca
    17761 accgccgacg gaggcggtcg tcgccatgct ccgcgggacg gagtacgaca ccggtctgga
    17821 cctcaagaag ctcaccgcca tctccgaata cttcgaatcg atccgtaaga agtatcaggc
    17881 cttcgagagc ggtttcaccg gcatcgacac caacgtactg gtgtaccaga tccccggcgg
    17941 aatgatatcc aatctcatct cccagctgag ggaggccaag aaggaggacc gcctggcgga
    18001 cgtctatgac gaagttccga aggtcaaggc cgatctcggc cacgtcccgc tggtgacgcc
    18061 aacgtcccag atcgtcggaa cgcaagcggt gttgaacgtc atcaccggcg agcgctacaa
    18121 gatggtgacg aacgagacca agaacctggt tcgcggccta tacggaaaga cgccagcgga
    18181 catcgatccc gccattcgca agaagatcat aggtgacgaa agaccgataa ccgtccgtcc
    18241 ggccgatctg ctggagccgg agttcgagaa gctggccaag gagatagagg agtacgcctg
    18301 caaggagaac atggcctgct ccgaggagga cgtgctctcg tacgccctct tcccccaggt
    18361 ggccctggac tacttcaagc accgccagat gatggaaaag ggagttaact atcgcgatct
    18421 ggcggccatc gctgtcctgt acatgcgctc cacggagaag catgtctcca acaatgaccg
    18481 gggcaacggc aacgtggacg cctggaaatg cgcggcgata aacgaagcgg tgggccgcgg
    18541 ggggtggccg ctgtgaagct gcgcatcacc gtcaacggcc aggagtacga ggtcgtcgtg
    18601 gagaagaacg gaggcgatta ccgcgtcgcc ataggcgatc acgtcttcaa gtgcatagtc
    18661 aaggacgaga aggtgatggt gaacggtgag gtcgcgccga taatcatcga gggcgatctg
    18721 gaggaaggcg ccaaggtcat gtctgacgac cgtaccatgg aggtcaagct gcaccatgtg
    18781 cgggaaatag agcacatcgc cctggaagag atggaggacg gcggaaggtc cgaaagcgct
    18841 tccggtgccg tcctatcgcc catgcccggc aagatcatgt ccgtcaaggt gaaggtcggc
    18901 gatacggtcg ccgccaacca ggtggtctgc gtcctggagg ccatgaagat ggagaacgag
    18961 gtgcagaccg aggtggccgg caaggtcaag gaggtcaagg tcaaggccgg ggagacggtg
    19021 gagggcggac agcccctcat cgtggtggag ccttagaagt ccagggcctc cgccgcctcg
    19081 gtcatctccg ccctcatgtc cttggcggag cagatggtga cgcaggcctt gctaccgatg
    19141 agcagggcct ccgccgcctt ggctatctgt tcggccgtca ccgcgtttat ttcggccagc
    19201 tgttcctcga tgctcatcac ctttcccctt tccaggaact gcccgatatg cgatgacatg
    19261 ttctggtccg ggcggcaggc gttgcgcaga agcgatccct tgagaccgtt cctggccttt
    19321 tccagctcac cttcgttcag cccttccttc ttgaaacggg aaagctcctg gccgaaggtg
    19381 tcgaagagac gcgggacctg ttccatggac gtcgagcagt aggtcatgag cgccccgcag
    19441 tccgggaagg tcaggggata catgcttatc gagtacacca gaccctccac ctcccttatc
    19501 cgatggttta ggcgggatga agttccgccg cagagcacca tggtcagcat gccctgggcc
    19561 aacgacattt tgtgcgcggc cgaatatcct ggcacgccga tcccgatgta ggcgcggtcg
    19621 gaacccttct catagaagtt cactccagtg cggatctccg gcctgcggcg cctcttgacg
    19681 gcggccttgc ctcccacggc atcgaagcgc ccagcccatt ccagcacccg ggagaaatcg
    19741 acgttgccga cggcgcagat caccacgtgc ggcgggtgat agtgcgtacc gtggtagttc
    19801 agaaggaact cggaatcgaa accgtccaag ctctccggcg tccccagtat ggacctggac
    19861 agagggttgc cgcggaagat ggactcggac atcttggtgc ggagatgggc cgcgggatcg
    19921 ttcatgcgca tgcctatctc ctgcttgacg atgttccgct ccagatcgac cagctcgggg
    19981 tccatgcgcg ggttcaggaa aacatcggaa agcaggtcct cggcggtctt cagcgactcg
    20041 tcgatggtga aggcgtagaa gcaggtgtgc tcgtgagtgg tataagcgtt cagataaccg
    20101 cccgaggcct cgatgccctc gttgatatcg cggtaatccc tggtcttcgt cccccggaac
    20161 agcatgtgct ccaggaagtg cgacaccccg ctctccttca ccttttcatc gcgggagccg
    20221 acggtggcgg cgacggaaag cgccacggta tgaacgtaag gcatgctctc cacgatgacc
    20281 ttgatgccgc ccggggtgct cccgaccttg atgtcctggt ccacccttcg gctttttccg
    20341 gaacggtcca tgagcgggat atgcttcccc cttatgaaat ggatgccgcc ctcagccttt
    20401 ccttaccttc cgccgtcccc tctccttgcg gcggcgcagc caacggtaca ggtccgattc
    20461 gtaaccgttc tcgtgcccgc atcgagggca tctctcgtat cgaacgtcga cagcgttcca
    20521 gcccttgata cgcgggggga actggtggcc gcatttctcg caaatgcgga ccgttctcac
    20581 ttcttggaca ccggcttcgt actgagatag gtcttcagac tgtcgatgtc tagacgcagc
    20641 atgaccatgt cgcccacgct cttgacgtcc ttggacagaa tggatatctg cgacgatggc
    20701 gccagaccct tctgaaggtc cagggactgc ttggcggtct tgtccagctt gatccccagc
    20761 ttgccgatct cccagctcct ggtcgtgtca aagtagacat tgtccatgaa ccctatcagc
    20821 ttgccgtcct ggcccaccac cttcttgttg agcatgtcgc cggcggtcat gaagaccttc
    20881 ttctcgtcca ccacgacctc cttgacctgg tccatcttga ccgccagggt gacggtgtcg
    20941 ctgaccgagg atacctgtgg agtggccacg aatatcttcc gcacgcctat ggccttcttc
    21001 ttgagcccca aggcggcctc gttccccttc cgcacgctta tccggatggc cggcaccttc
    21061 cagttgtccg tgtcgatacc gaccccgtcc acggtgccga tgatgatagc gtcggagctg
    21121 atgacctcct tacccatgat gtcctctagt cctgacatgt tctccctggc gatgaactcc
    21181 ctagattggt attaatccta tcgcctctaa atcgattttc aggacgcgac gatgagcgac
    21241 ttgaccatct atcgcccgcc atcacgacct tcggtccgtc gggctaatct gatgatgggg
    21301 caaagtcgag aaggcgcatc agccgctgcc gtccgctagc gtgaaacggt tcggctctgc
    21361 tgcctcatgt actgcgccag gtacatgtcc gtgccgctac ccagtccggt ggagccgctt
    21421 cctttccagc cgccgaaggg ctgcgccccg accatagctc cggtcgtagc gccccgagcc
    21481 cggttggcgt aactgactcc cgcctcgatg ttctcgaaga agtagttcac ctcgtcctcg
    21541 tcgtccgagt atatcccgga cgtcaggccg taatccacgt cgttggcccg gcgcaccgcg
    21601 tccttcaggt cggtgaagcg ctgcacgcac agtatcggaa ggaagagctc gttcctgacc
    21661 aggaagtggt cctccgggag tccggtgacc aacgtagggg tggcgtagaa ccccttggac
    21721 agcttaccct tcatcgcctc cccgccgacg tgcagcaccc cgtcgatgcg ggcctgatgg
    21781 gaatatccca gataatcgtc caacgccttc tggtgtatga ccggcccggt gaacgtcgcc
    21841 ctttcccggg gatccccgac ccgcgatcgc gcaaggtgct tcatgaggta tatcatgaac
    21901 tcgtcgtaca ccagctcgtg aacgtagacc cgggagcagg cgctgcactt ctggccggag
    21961 taaccgaagg ccgagatggc caccccggcg atcgccttgg ccagatcggc cttctcagtg
    22021 actatggccg ggttctttcc tcccagctcg gttatcaccg ggatagggta gcggcgcggg
    22081 gacgagagca gccggtaccc cacctccttg gagccggtga aggcgatccc gtcgatcttg
    22141 tcactggaga cgagcgcctc ccctgccacg gagccgctcc cggagagcaa gttaataaca
    22201 ccgttcggaa cgccagccct ctcgtacacg tcgtagagca tgtgcaccgc cagaggcgcc
    22261 ggggtggacg gtttcagcac cgcggtgttg ccagttatta tcgccgcggt cagcatcccc
    22321 gccgatatgg cgatggggaa gttgaacggg cagacgatgg cccatacgcc gtaaggccgc
    22381 atgacgctga tcggcttctc gtccgcatag gccggttcgg tatcctcccg gaagccgtgg
    22441 cgcgcttcca tgcggtcggc gtagaacgag atgaagtcca ccgcctcgtc cacctcgccg
    22501 accgcctcgt aacggttctt gccgttgtct atcgttatgg ccgccgctat ctcgaacagc
    22561 tcgcggcgca tgatctccgc cgcctttcgg aatatcacca agcgcttgtc caggtccatg
    22621 accgaccagg tctggaaggc ccggcgggcg gcggacaggg ccagggacgc ttccttctca
    22681 ccgcccagtg agaactcccc caggaccagc tcggtgtcga tggggctggt gtctgtgaaa
    22741 tatttacccg ttgggaccgg tttaccgtct atcaggctct cgtatgtcga cccgacctcc
    22801 agggattgga cgaacctctc caccgccctg tcgtatctgg tgtggaacga cgattcctcg
    22861 cctgccttga ccatgctctc gtaggtgttc aggttcctga agctcatgac cgcgccccct
    22921 tcactcaata ggatggatga caataataag gcatcgaact ttctgttcgc ctaaccccgc
    22981 cgaaaaccgc acaaatttat atcgtaggca acccgatggc ctatgtcgtt ccaaggagtt
    23041 gttgatctgt cacccgagcc gtaccgtacg aatgccaagg aggtcctgga cctggtccga
    23101 tcgaaacgcc tagccctgct ctcggacgtc aacggcatgc cgacggaccc ggtggccgag
    23161 gtccggcgaa ccttgaccgg accgctatcc gctcccgacc tgtggaaggt ggacctcgga
    23221 gcgtgcctgg acctggtcga ccgggacctg gccaagaagg ccggtctgga accgatggtc
    23281 gtccgtgagc ggaaggtatg ggagcaggcc gggatgctgg cccctatgga cgccatgccg
    23341 tccggtgacg ctttcgctct gctactggcg ctgcgggagg ccctggcctg ttcattgctg
    23401 cgcttctgcc tggacgcgaa cacggagaac atcgagcatg atgtccaaga ctccgacctg
    23461 aaggaagggg tcctgcgcgg cctcgccctg gacctgggaa aaggatggta tgggttagga
    23521 gcaaccaccg ttccggccag caaaggggat gctggtctgc gctctttccg ttccttgagg
    23581 cggcacctgt gccggaagct cggaactacc tccgcccagc tacctttggt tcttcggacg
    23641 acagagcttg acatcgccct gggagaggtc ctcttgggct ccccggtctc gctcgaaggg
    23701 ttggcgttcg atgatatctg ccaggagttc cttttccata ccgttcggga cgtgttcggc
    23761 ggttgcctag aaccggaagc tgggatcgga atggagatcg agcgccggag gtggctgagc
    23821 ggtctgccgc acaggtacga accgcctgcc ccggccgaag ccagcaacgc cgccgtcata
    23881 ggtctcggat tcttaggcgc ctcgctgctt tccgctctcg ccataactgt caccaaggcc
    23941 gccatctccc gaaaggggga cgctcccctg gaatatccgg agacggcgta ctcgttaccg
    24001 tgcataatgg gctgggacgg ggaggaggta gccagcctgg gcaccttgct caccgtgctg
    24061 gaaaggcatt cctcattgcc ttcggagagg ggactggcgc aggccttgga ggccggacgg
    24121 acggcgatga tcgccgccga ggcgctggaa gcgttacgat atctggacgg ggacccgcac
    24181 gttggaacct ccgcggtggg cttcatcccc gacaaggtgc tcagggaact gggcctggcc
    24241 ctcgtggacg acaccattcc cggagcggcc gtgatcatgg gcatccccct ggaccgccgt
    24301 cagctggtga ccaccgttcg ggagcttcag gcgcgcggaa tgctgattat ggccgccgac
    24361 gaggtggtga aggtactgca ggagaacgag gtgcagatgg gtctgggtat gatgctctac
    24421 cccctgggta atttcacgca actggtgcat tccttggact tcgtggtccg cgccgcccta
    24481 tccttcggag ggttgcagaa aggggactcg gagcgtctgt ccgcctacct ggcgaagcgc
    24541 ccgaaggcct tcgtcctgca ttacggaccg cttgacgcca gccgggcgtc gctggctttg
    24601 gcggcgctgc tgcatcacgt tccgataatc accgatcagt tggtcgaggg cgttcccgac
    24661 cttctgatac acaaggaacc ggcctccatg ctgcaaggag gcctggaatc cagggacatc
    24721 aggaccgccg tgaccctggt ggacataccc gtgcccttcg gcccagcgtt cgaaggagaa
    24781 acggttcgcc gaccggacac ctacttcgag gcgggcggcg gcagaacgcc gtccttcgag
    24841 ctgctgaaga tgcgcccgga ggagcaggtg aaggacggat ccataatggt catcggaccg
    24901 gacgtggacc gccttcccga gggttcgcaa tcgccgttgg ctatactggt ggacgtgttc
    24961 ggcaagcgca tgcaggagga cttcgaatcg gtgatggaga ggcgcatcca cctgtacctg
    25021 aactttgccg agggcgtgtg gcacaccggg cagcgcaaca tgaactggct gcggctgagc
    25081 aagaaagcgt tccgagcggg gttccgcctg gagcatctcg gacggatctt ggtcaccaag
    25141 ctcaaggagg agttcgggaa catcgtgtcc cgcgtgcagg tcaccatcgt caccgacgag
    25201 aacgagctga gaaagaggat gccggaggcc ctggccgcct atcagataag agaggagcgc
    25261 atggccggcc tcaccgacga gagcgtggac acatattact catgcctgat gtgccaatcc
    25321 ttcgctccgg accacgtgtg cataatcacg ccggagcgcc tcgggctgtg cggcgccatc
    25381 aactggctgg acgccaagac cgggaaggag atcgttccct ccggtccgaa ccagcccatc
    25441 gccaagggcg aggaggacga cgctggcaaa ggctcctgga aaggggtgaa cgaggcggtg
    25501 accgccctga cccgcgggaa gataaccagg ttctgcgcct acagcatgat ggaggacccc
    25561 atgacgtcct gcggctgctt cgaggtcatc gtggccatga gcccggacat gcagtccgtg
    25621 gtcgtcgtca accgcgagtt cccggacatg accccggtgg gcatgaagtt ctccaccttg
    25681 gccgggagca taggcggcgg aaagcagacc ccgggattca tcggcatcgg aaggaagtac
    25741 ctggtgagca agaagttcat ctccgccgac ggcggcttcc tgcgcatctc ctggatgcct
    25801 tcgtcgctca aggagagcat gagggaagag cttattaata gggccaggga attgggagcg
    25861 ccagactttc tggataaggt ggctgacgag acggtggtca ccgacgccga aggcctgttc
    25921 cagtggatgg tcaaggtggg ccaccccgct ttggggctgc ccccgctgct ttgaggtgag
    25981 aagatggaag tgccggtgcc aagggagaaa tgggcgggtt cgatcggaga gatggagctg
    26041 ggagcttccc tggaaaaggg cgggtcccga agctcgttgc gcctgggcgg caacaagggc
    26101 ctgccattcc tgtcctttga ggacccgact agccgcaacg tcgctctggc cggtttcgtc
    26161 gccgactcct tagaggacgt gccgctgccg gtaaagaggg cgttcggaaa cgctgtcaac
    26221 gacccggcga gatgggccgc cgcctggaag gagaagggcg cggacctcat ctgcctgcat
    26281 ctgacgtcca ccaaccccga ggagaaggac gtatcgccgg aagaggccgc ggcgaccgtg
    26341 atggccgtca tgaaggccgt ggagcttccg ttgatcatct acggcagcgg tcacccggag
    26401 aaggacgcca aggtcctgga gaaggtgggc gaggcggcca aaggtgaacg gctactattg
    26461 ggccaggccg aggagggcgg ttacaagtca gtggccgcgg cgtccatggc caacggtcac
    26521 gcggtgatcg gtttttctaa cttggacatt aacctggcca agcagatagt catcctgctc
    26581 acggattacg gcgtcggacg aggcgatgtg atcatcgacc cgttgatggc cgccctgggc
    26641 atggggctcg agtactcata ctcggtcaac gagaggatca ggatatccgc cttgtccggg
    26701 gacgccatgc tgcaggtgcc gatgatatgc gactgcgtct cggcctggaa ggctagggag
    26761 gcctcggacg acataccgca ggccggcgac accctggaaa ggggcatctg gtgggagagc
    26821 accaccgctc tggcggcgct gctgtccggg gcggacatac tggtgctcgg gcacccgggg
    26881 tccttgcaga tagccaagga cgccttgaag ggcttcaggg gtgaggcctg atggccaccg
    26941 cgatagagat cttcaagcat ctccccaaga agaactgcgg ggactgtaag ttcccgacct
    27001 gcctggcctt cgccatgcag ctagcgaaca acaaggccaa gctggacgac tgcccgcatc
    27061 tcagcgaggc gggacgtaac gccctggcca gctcatccgc tccgcccatc cgtcttatca
    27121 aggtcggctc cggcaagaac gcggtggaca tgggcgacga gacggaactg taccgtcacg
    27181 acaagcgctt cttccacccg gtggcctttg cgttacggat agcggacgac ctgggggagg
    27241 acgacctata caagcgcctt tcctacgttc ggtcgctgcg cttcgagcgg gtgggccaag
    27301 tactaaagat ggacctgctg gagctggaat gccgctccgg cgacgccgat aggttcgcgg
    27361 ccttcgtcaa aaaggtggcc tcggagtccg agctgcccct ggtccttcga accaaggacg
    27421 cggcggccat gtccgccgct gccaatgcca taaaggaaaa aaggcctctg ctccatgggg
    27481 cggacgcttc gaacctcaag gagatgtgcg tcgtcgccaa gagctgcgct tgccctctga
    27541 ccgtaggcgc ggacgacctc aatggcctgg cggacatggt ggaagcggta cgcaaggaag
    27601 gcgtggagga catggtcctc gatcctcgac caagctctct taaggagctg ctggaaagat
    27661 gcaccatcat caggcgcagc gccatccgaa agacgttccg cgggctcggt tatcccatat
    27721 acctatcgat accggccgga cgcgacggca tgctcatggc ctccacggcc gtcatgaagt
    27781 atggcagcct gctctccttt gaagaacttc cggcatccaa cgccctgccg ctcatggtcc
    27841 tgaggcagaa catctatacc gatccgcagg tgccgatcca ggtcaagccg gacctctacc
    27901 cggtgaacaa ccccgggccg gacgctccgt tgctgttcac caccaacttc tcgcttacgt
    27961 tcttcacggt catgtccgac ctggagaaga gcaaggtgcc ggtctggctt caggtggttg
    28021 acacggaagg actgtcggtc ctgacggcct attcggccgg caagctgacc tcggaatcgg
    28081 taaagaacgc cctgcaatcc acgggcgctc tggagaggtc taagaaggga accttggtga
    28141 tcccgggcat ggtggccagg atggccgtca agctgaacga ggccaccggg ctgcagataa
    28201 tcgtcggtcc caaggaatcg tccgggctgc cgaagttcct gaggtcctga cggtttaaca
    28261 tctcgaagaa cgtctggaaa tcattattac cagacattcc gttgcattcc taacacccca
    28321 aggtggagat cggatgcaac aaggacctta cgacccgaac cagcctggcc agcaaccgta
    28381 tcaaggccag cagcaggggc cgcagcagtg gcctcagcaa aacccaccca ataattatca
    28441 acagccgcct caacagcagc cgcagtacca gcagcagtac caaccacagc aataccaacc
    28501 gtacccgccg caacagtact accagccgcc gaagaagaag cggaacatga agctcatcgt
    28561 ggccgtcgtc gccgtggtgg cgatcttgct gatcgcgtcc atggcggtgc t
//
LOCUS       DAOPZI010000019        28361 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1655_length_28361_cov_9.878824, whole genome shotgun sequence.
ACCESSION   DAOPZI010000019 DAOPZI010000000
VERSION     DAOPZI010000019.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 28361)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 28361)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28361
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1655_length_28361_cov_9.878824"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(79..178)
                     /locus_tag="PKM11_04985"
     tRNA            complement(join(79..113,139..178))
                     /locus_tag="PKM11_04985"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(140..142),aa:Glu,seq:ttc)
     gene            315..1145
                     /locus_tag="PKM11_04990"
     CDS             315..1145
                     /locus_tag="PKM11_04990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47895.1"
                     /translation="MAANKGTSYCSKCGKPFVGLMIVKAIAAIYAIYFFALFFFNLLV
                     MGDDWMLAQLSFLEPFFPFGDEYIAISIVLLIIGLPIIMAGIYPGVEKMYKGNGASAC
                     KDCRALIAREQADAAEMARAKQEAQAYAYMAKVDGLEKGDAWIGKLIRSWKLDNPNKI
                     PEECMLDDLVMAHNMERAGNYEKAAVILEKYLFWEEAGRVRRLDDQKIIKHITVDMNA
                     LINQVGNKGLAIPYKCSSCGASITIDKDSKQDGLKFCSYCGTAYNVEDMTKIIQLALE
                     "
     gene            1245..1583
                     /gene="eif1A"
                     /locus_tag="PKM11_04995"
     CDS             1245..1583
                     /gene="eif1A"
                     /locus_tag="PKM11_04995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor eIF-1A"
                     /protein_id="HNX47896.1"
                     /translation="MSNEPYNQGSGAESEEILRLPYPKIKEGEMFGIADQLLGASRIK
                     IMCADGKSRMGRIPGKIKKRMWIREGDLVIIRPWDFQDDKCDVHYRYTKTQASHLSRK
                     KVLPKNLDIF"
     gene            1591..2382
                     /locus_tag="PKM11_05000"
     CDS             1591..2382
                     /locus_tag="PKM11_05000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protein kinase RIO"
                     /protein_id="HNX47897.1"
                     /translation="MPTEDKQILKLDRMVEKARLTRSFESSQEGRKVMEEVFDNLTLG
                     VIFKLTCEKRIASVDFPVSTGKEGNVFRATAPDGTLVALKIYRTSNSTFKNIAKYIEG
                     DTRFKGLTGNPRKLIYAWCTKEFKNLNRLEHAGVRVPHATRFLKNIIVMDYLGDQVMA
                     APQLRNVRLEQPQKVYREILRFMKRAFQKAKLVHGDLSEYNILMHDGLPYIIDVGQAM
                     LTDHPNAIEFLKRDVKNINRYFRNIDVKVWSDETVLKYVQGVREK"
     gene            2379..2924
                     /locus_tag="PKM11_05005"
     CDS             2379..2924
                     /locus_tag="PKM11_05005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HNX47898.1"
                     /translation="MKIVKIPKERVGALIGQGGETKKFLEQKTGIRIIIDAEEGEVSF
                     DERNIQDPLLPLKIMDIVKAIGRGFAPHKAFRLLDDDEYLEIIDIDDYVGKGTNQLVR
                     MRSRVIGTGGKTRRIIEDLVGVHISVYGDTVGIIGNSVQMVVARNAVDMLLSGSEHAT
                     VYKFLERKRAELHIAEMGFDL"
     gene            complement(2925..3860)
                     /locus_tag="PKM11_05010"
     CDS             complement(2925..3860)
                     /locus_tag="PKM11_05010"
                     /inference="COORDINATES: protein motif:HMM:NF024247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S double cluster binding domain-containing
                     protein"
                     /protein_id="HNX47899.1"
                     /translation="MPFRTKLMAENTGMLRLLRERGYEARSMSVSHLDEVREDVEGLY
                     RKGLLDEQLYKESLFRFKYFVPVSFPEAKSVIVVSVPQPTCEVSFNVNGRKVRTIIPP
                     TYARAVDVDMEIVELLERGDGNGVHLMRAILPHKTLAARTGLVEYGRNNISYVPRYGS
                     FHRLTSFFTNRELPDDWQDMKVMDRCAECGACVKACPTKAIAEDRFLLHAERCLTFHN
                     EMPNEKAFPDYVLEGAHNAVIGCMICQKVCPVNATVRNWMVHCTEFNEDDTSYLLEGD
                     FSGPRAKKLMERLEPLGLELSLFPRNLKALLNNGQ"
     gene            3938..5173
                     /locus_tag="PKM11_05015"
     CDS             3938..5173
                     /locus_tag="PKM11_05015"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0031119 - tRNA pseudouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(54/55) synthase Pus10"
                     /protein_id="HNX47900.1"
                     /translation="MKEVLEQALKAQDRDLCDHCLGRLFAHVGTGTTNLKRGEELRAL
                     IDEDRSSRGLGPMNHERCWLCDEIFDQVPRYAEAIDLKLQEVQFDNFLVGTRVDPAVQ
                     AKEEELWSIVGQEHAEPIKSELNREIGKAVFAINGKDVEFKSPQVVALVDTRFAHVEL
                     DVAPLFLYGRYRKLSREIPQTKWPCRMCQGKGCQRCNNTGKMYQTSVQEQIGDVILPH
                     AKAKEHFFHGMGREDIDALMLGTGRPFVIEISSPVVRTLDIAALQEEINQKAQGMVEV
                     EQLRLSNREEVRLVKDSAHDKEYRVQVSIHGKVNKGKVDEVVRTFNRTRIVQRTPVRV
                     SHRRADLKRERYIVYVVLEDFQDDRMTLRLRTESGTYVKEFVHGDQGRTLPNLSEMLG
                     VPCTVDALDVIGVIDKSEE"
     gene            5176..5472
                     /locus_tag="PKM11_05020"
     CDS             5176..5472
                     /locus_tag="PKM11_05020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21e"
                     /protein_id="HNX47901.1"
                     /translation="MVKASHGQRGKGRNILRRSPRARGLSPITHEFVQFDVGEQAHIH
                     LDPSIVKGAPHLRFHGKTGTVKAAQGRAYVLSVRDGDKYKTVVSRPEHMRKVKN"
     gene            5484..5816
                     /locus_tag="PKM11_05025"
     CDS             5484..5816
                     /locus_tag="PKM11_05025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47902.1"
                     /translation="MSKDRYVTLAEVKEMLEAEAESREFTPEQRLAFEHAKGAKMSAK
                     QARELKGKLLELEFVGDLNNAEAVAVKITDLLPTHFDDVRLIFQKERRIIEKKQGEQI
                     IKLVNEYL"
     gene            5829..6377
                     /locus_tag="PKM11_05030"
     CDS             5829..6377
                     /locus_tag="PKM11_05030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF655 domain-containing protein"
                     /protein_id="HNX47903.1"
                     /translation="MEDYAHILDYLPQGLPMDRGLRKESVAYALGSTELKLFELVPKP
                     GEIISPGDVVYIGKDMDKRDKILHVKRRVSFEELNAGSQNELPFVILEVVKENEMHYV
                     KFFNESEAITTRYHVLELLPGLGKKTMLAILDERKKGPFKSFADIAARIPTFKRPEKV
                     VAKRIELELADSTQKYRVFVSR"
     gene            6379..7167
                     /gene="rsmA"
                     /locus_tag="PKM11_05035"
     CDS             6379..7167
                     /gene="rsmA"
                     /locus_tag="PKM11_05035"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HNX47904.1"
                     /translation="MISIGELRSLLERYGVRPSKSRGQNYLIDRRVAEREVEYLDIAE
                     NDRVLEVGPGFGILTSALLERTSKLTAIEIEEGAVRYLRDTFPQMEVVQGDFLETDPP
                     QFDLFISNVPYSISSPLLFHLLDMKFKRAVIMVQREFAERMAAPAGDDEYSRLSVNVF
                     YRAECKLLENVPRSRFWPEPEVDSTVVLLTPRPAPFPLRDEKHFLRLVDVLFQQRRKK
                     IGTVLKQKRMLPDDRSGIPFLDERVERLTPAQIAELSDSLSSQS"
     gene            7215..7985
                     /locus_tag="PKM11_05040"
     CDS             7215..7985
                     /locus_tag="PKM11_05040"
                     /inference="COORDINATES: protein motif:HMM:NF014635.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HNX47905.1"
                     /translation="MGSDGIDITEIGKVLGTAGHLALEPLCVFESELRPRKGRPFGEV
                     DRCIAKAVLMCAQGKEELLYIGEDARSGICPGGQSWMGLAEMAEGLKFFISTGSPSFR
                     HGEAEYLKRDPEMVLRSKALVGRIRPPEKYLVVTQCRHFRKEDGLPRALLLFVEAEQL
                     RNLLSLHHFGTPDAFTSTCAPWGPSCASFLTYPAGLASNCPDQALIVGPVDPTGNSWM
                     PPNLMSLGLKVKDAERMVRDIPSSFLSRRPQVAFPDGR"
     gene            8052..9242
                     /locus_tag="PKM11_05045"
     CDS             8052..9242
                     /locus_tag="PKM11_05045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HNX47906.1"
                     /translation="MLIGIVGKPNVGKSTFFSAATMATAEIANYPFTTIKPNKGMGYV
                     RSKCPHLDFNVKCTPRNSACENGVRLVPIELLDVAGLVPDASLGKGLGNQFLDDLRQA
                     DAFIHVVDASGSTDAEGNAVKPGSHDPVEDLQFLEREINQWIKGIIMKGFDKLARGAH
                     LEGSKIDQVIYERLTGLGVTEVQVSAALRTSEMPHKIIDWKDEDLYRLAANVRKMSKP
                     MFIALNKADAADPELIKRLSALDGYMSVPTCAETELALRRAAKAGLVSYVPGDKSFKV
                     NDPSKLNANQKKALDFMAHVMSMYDGTGVQKCLEAVTYKLLDQIVVYPVEDETHLTDH
                     EGRVLPDAHLLRKGSNARDLAYKVHTDLGDNFIRAINARTHRVVGQDHVLENEDVMTI
                     VAKR"
     gene            9245..11680
                     /locus_tag="PKM11_05050"
     CDS             9245..11680
                     /locus_tag="PKM11_05050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase domain-containing protein"
                     /protein_id="HNX47907.1"
                     /translation="MGEWDVRLLTASYSKGDNDSIVVELFGKTRDGRSITMRKTGFRP
                     YFHVAAPPEDVLPYVQGKDDYLGIEPIELFLINKGRVQSCSKVIIKFPWAVPQYRSEL
                     KRQGMEVFAADIPFHHRFIYDNDLPACFTARGEEIKGEYTTDLVINLRGFTEIPPFTP
                     KLKVMSFDIENSITDETIYTICYVIKDEGGIRAGEPIFGTEKEIIERFTEAIQMEDPD
                     VITGYNIDGYDIPFIMERAKKYGIDELKWGRDRSNPRRVMNKFWRCTGRLIADAWWAV
                     KIEIKPKQETLNAVSKSLLGEEKLDVDMKMKVGEDYDPRAIDKEWANNRDKVLAYCTR
                     DAELALKILGKVGRIRKGMDLAAVSRMPVDDVLNSGSSQLIDAIMIRAADRHVPQVAV
                     PLTGNYDDDEENAIEGGYVHEISPGVYHWVCVLDFKSMYPSLIISRNICFTTRDDAGP
                     IVSPLGVHFLSKEQQPGILPTILADLMRRRDETKGLAKKAKDPEEAHYYDGLQGAIKI
                     LMNSFYGVFASSFYRFTDRSIGGSITAFARETTKGIIKALTDEGVNVIYSDTDSIFVQ
                     SPHDNLEGSLEFGRGLANRFSKEGGSLEFEKIMEPLFSHGKKKRYVGRMVWPKEELVI
                     RGYEVRRTDSFDLQSESLMTMFEFIMDGKTDEAVKVARSYVQDTLAGKVPLEKLIISK
                     GCRNFKEYANPDAQATVQTAKKLMEMGYEFVPGMKVSWIVTNFRKKPQEVQPYISGQE
                     FTYTPDYRYYAERLAQTLSRATEVFGWGEKDLLSGNQQANLFDYGPEQDRPKIKLEQV
                     KKTDKKLTLDDYF"
     gene            11813..12451
                     /locus_tag="PKM11_05055"
     CDS             11813..12451
                     /locus_tag="PKM11_05055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15e"
                     /protein_id="HNX47908.1"
                     /translation="MVEKKVDDNEDGPRPVNGKSMYSYISDAWDRPDASYVKDLMWER
                     LIIWRREPNFIRLERPTRLDRARALGYKAKQGIIIVRGHVRRGGLQKRMGYKGRRAKR
                     EGMKKITMGKSLKRIAEERAAKRYPNLEVLNSYWVGEDGKKVWFEIILVDKHHPSIKV
                     DKNLNWLCNSANKNRVFRGKTSAGRKGRGLHWKGKGAEKARPSVKAHDRQIK"
     gene            complement(12461..13312)
                     /locus_tag="PKM11_05060"
     CDS             complement(12461..13312)
                     /locus_tag="PKM11_05060"
                     /inference="COORDINATES: protein motif:HMM:NF014923.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing protein"
                     /protein_id="HNX47909.1"
                     /translation="MGLLLVRYAEMGLKSPGVRRYFEKVLTYNMMAALAQERLEAFVE
                     SQYGRLFVTTDRPEEAATVLRRVFGISSLSHVQQCTSEVKDIRRLALEVATPLIKDDS
                     TFRVEARRNGVHQYTSMQLAAQAGEEIFEANRHRGVRVDLHHPDLTVYVEVRDKRAYV
                     FSEYLDGPGGLPMGSQGKVVALIGNDRDALAAWMMMKRGCRALFVVENEEAMRTLERW
                     DPEPRKVHGPAVKAVHVNKAFGLVVGWSLDELQENRTLHAEVPIYHPLIGMGNEEVER
                     RLKEIKG"
     gene            13388..14233
                     /locus_tag="PKM11_05065"
     CDS             13388..14233
                     /locus_tag="PKM11_05065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HNX47910.1"
                     /translation="MEPLVLLLIALLCVSAGTVGALMGIGGGLIIIPLLTLGFGIPMQ
                     EAIGASLIGVIATSTGAASKYVKQGLTNIRLALFLEMSTTIGSIVGALIAVYTDQTIL
                     FLLFSMLLVYSGYTMLRRTEKLFTPEQAEAEGQLVDLSCQYMDPKDSCQVSYGVKGQG
                     KGLAYSSVAGLLSGLLGVGGGLVKVPVMNVCMCVPLKAATATSNFMIGVTALTGAIIF
                     YGHGLLDAYLCGAVALGTFAGAYLGTILMARYSANELRKWFSVLLFLVAVTMVLKAFG
                     LWGGP"
     gene            14233..14571
                     /locus_tag="PKM11_05070"
     CDS             14233..14571
                     /locus_tag="PKM11_05070"
                     /inference="COORDINATES: protein motif:HMM:NF019459.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1634 domain-containing protein"
                     /protein_id="HNX47911.1"
                     /translation="MPSQSTLCGVVRPILRWGMVLSLILMLIGLALGVIAGEQEATVV
                     PLEKIPFQLMEMDPAAFLTLGIVLLIATPLARVIGALCVFIRERDRKFILVSMAVLLS
                     VFLAVILGAA"
     gene            14631..15962
                     /locus_tag="PKM11_05075"
     CDS             14631..15962
                     /locus_tag="PKM11_05075"
                     /inference="COORDINATES: protein motif:HMM:NF024241.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HNX47912.1"
                     /translation="MAKDRQKDDRWYYSFLPYNISGGSTNALIPLFITEGLKGTVAQV
                     GIVSAATSLASVPAGILWGNLSDTSKRRVPFVLAGFLGVAFSLILMGLSQSISEYYIA
                     NFIFGFLGAAIAPVGTVMVLESFRKDEWPKRLGDFSRVGGIGWVLGLLLGTIWLVAFP
                     SDGDAASMRALFILAGVLGFVSVFLGWRFMREPLENLSRHQVPTVDVLNVPSYLMEKL
                     RFMPQRLLYVVEMSQKNLRLRNFPTNLRRYYAVVFLAFTGFLCFYVALPTYLARQIGM
                     SSAEVLAVYLASSLVSALMYSRAGRLVERLGGRKVQTMAFGLRVLIFPSFFLVTLLPL
                     DLAGIFLLMCVLSGLAGMCWALLAVAGDSLVAKMSYRSFRSQSMGMYSSVRGVSTIVG
                     SLFGGLVAQYFGYVALFAISSLFIICALLLLRSTNVEGEADDPRPEAALEQ"
     gene            complement(15951..16418)
                     /locus_tag="PKM11_05080"
     CDS             complement(15951..16418)
                     /locus_tag="PKM11_05080"
                     /inference="COORDINATES: protein motif:HMM:NF024135.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HNX47913.1"
                     /translation="MEGVHLRKDRMRILVIYDTKYGNTERIAQLIAEELTGSGHEVSC
                     RRQSVSGEEDFIGVPLWVIGSPTHWGRASFRFNTLLRNAMKDAGNDHAIVTFDTRYEN
                     MHSGAADKMHRMLVKDGLRPLMGPQHFVVDGNELRPGEEEKARELGRTIASLL"
     gene            16569..17588
                     /locus_tag="PKM11_05085"
     CDS             16569..17588
                     /locus_tag="PKM11_05085"
                     /inference="COORDINATES: protein motif:HMM:TIGR00374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="HNX47914.1"
                     /translation="MSLGTKIRLGISLALIVLVVLASNPEEVWVALKDIRYELIFLVV
                     VLYLVNLVFKAYRWGVLMSHAGYEISFRTIFAAFSLSQAINNLIPGRVVGETSRIIEM
                     NTRKGVAVGKGLASVVTERIMDFAFLTILTVSSLLLLLADIVEEFRGYLVFLVVMMVL
                     ANLLFIYVLARPKLLLRMGAWGARLTSKVLKGEKGAKLSGKMMDTVVSFNDALRFKGD
                     HKRLIWPAVLTAIIWVNEIVRLYLIILALGVDVSMVAVIASASLASLSTVVLTAGSGN
                     VLMSSAVFTASGLDPHVAATAGLLSAITSIWLSVPVSLLAMIIDQRVRSSPSKGTDKN
                     QRGLN"
     gene            17606..18307
                     /locus_tag="PKM11_05090"
     CDS             17606..18307
                     /locus_tag="PKM11_05090"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HNX47915.1"
                     /translation="MLKNEEGNIEALTEDILAVYVDRKIDGEVLLIDDGSTDSSGEIC
                     DRLTKVHPNVRVVHHEKNLGRSYAIRTGFQQALGDVVIIMDADRQYEPKQIPLFLAKM
                     DEGFDVVTGWRRERTDTFIRRFISRTYNRFIIRRKFKLQIKDQNSGFKAFRREKAVAM
                     GFDPEGYQGLHRFILPLAALKGLKIAEVPIVHYDRPSGKSYIKFYTVPFITLRDFSKF
                     KKDHKEEIVALRQKG"
     gene            18317..19513
                     /locus_tag="PKM11_05095"
     CDS             18317..19513
                     /locus_tag="PKM11_05095"
                     /inference="COORDINATES: protein motif:HMM:NF021134.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="HNX47916.1"
                     /translation="MYGLGKLFEKVLGKLRINTPGRKLLLYAAVALLVYGSMIVVDNA
                     FLMSAIDPDLSHPDMDVYRARTQTILDGGLLYRDVHTETPPIINYLLVPAQLLGGDQH
                     DWVWSAYFSLFAFLLSAMMYLGLRHLDENKAYLAGMIILLSPYTIAESGTGEDESIVA
                     FIFILAVVLMLIKRRSSASAAIGIGVWTKMFPILLFPVHFLQQRDWRGRITSVLFLGM
                     ATGLIALPFVIMCWDDFSFFLNFYFLGDEGRPTGGHSIWHFLWMGGISLPSMVQLALL
                     GGAMAFAYLYPYYKKMPVWQSVTLMLMTFFIFYPKVHGGYWIMLVALLSIWAVQDKRI
                     WDRTFFAFLPMILATMFAQGETRAPPVEFYGSWLLGFFLALIGLIMFIDAVRLALKQP
                     AFTDKA"
     gene            complement(19515..19919)
                     /locus_tag="PKM11_05100"
     CDS             complement(19515..19919)
                     /locus_tag="PKM11_05100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HNX47917.1"
                     /translation="MVALTPDMQELFKGTKYFAMATASRDGDPNVVPIGMAILIDPET
                     IWIGNQFFHQTLVNLKENPRVALQVWTFGVPGCLKIKGNVKVVEKGADFEKMYQMVKE
                     RKPTLECKGLIIMKVTEVYDCRSGAEAGKRLL"
     gene            20193..20861
                     /locus_tag="PKM11_05105"
     CDS             20193..20861
                     /locus_tag="PKM11_05105"
                     /inference="COORDINATES: protein motif:HMM:NF040019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6198 family protein"
                     /protein_id="HNX47918.1"
                     /translation="MKKKMIVPGELTLAIGLTTVSMAVPLMVRAGFGISTISSLPYAL
                     SLIFDRISFGIWNLLFQICLLMILLAITKRFKWGYLVSFVLAIAFSLALDLFSVTLSS
                     LPSGLWMNMAYFAISYVMMCAGISLMVSSQVPLMITDAFINDLTLHFHVTFRRMKTIF
                     DIVCLVLSATLALALLGDLAGVGIGTIIMAFITGAGVQAVNKVVAKAVTIRPLIKTLG
                     RIAR"
     gene            20980..21822
                     /locus_tag="PKM11_05110"
     CDS             20980..21822
                     /locus_tag="PKM11_05110"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016208 - AMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HNX47919.1"
                     /translation="MIPYHKILIPTDGSDNTKAAIAYALKLAKLVGAEVTAISVNDTS
                     NYATASGTVGPDVTSSLYQLCEDAVRYVVEEGARSGVTVHTNIINGNPARDIVEASKA
                     HDLVVMGSVGRTGVAHLILGSVAQKVVRMAACPVLVVRNARPESDLTICRKLLIPTDG
                     SENTTIAIRHGLELAKAFNAQVTALSVSLAKDPDQISNMAVEQVAEEGRKMGLKVIGS
                     VVPGSPPEEIVKASFDHDLIVMGTAGRTGLAHLRLGSVAEHTIRGSACPVLVVRASVD
                     RPAI"
     gene            21906..23492
                     /locus_tag="PKM11_05115"
     CDS             21906..23492
                     /locus_tag="PKM11_05115"
                     /inference="COORDINATES: protein motif:HMM:NF024702.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HNX47920.1"
                     /translation="MVDAHPRTVYVPLLITALLLLSSFLVLVPGEVAALSEGDYEYEL
                     TGVPAVAAITKYTGAGGAVIIPATLGGYATTIIRHDAFNYGNGIHVTSVIIPSSVHTV
                     ENYAFANCEDLEKVLIGSGVSSIGDATFINCHNLNTILVHDSNLFYSSLDDILYNKTM
                     TALIKCPSAKAGDVTIPDTVTSLRYGSFDDCRSIENLVIGSGVTEIGRYMFESVDDLK
                     TVTFSAGSSLHTIGERAFSACENLESFDAPSGLLTIENEAFQRCKSLVVFDLPSGLES
                     VGPGAFAGCESLVNMTVPASVMEIGLYAFSGCKSIAWFDVESENENFCSIDGVLYNKT
                     ATVLMQCPGGKTGNLTIPDSVIEIAMYSVAGCIITGARIGNGVEKIGVYSFYACTKLK
                     AVEMGDSVEIIGGGAFYGCKLLKSIEVPATVTEIQVQAFAECLTLNNITFLGSSAQIE
                     VGADWILHTSWELQGHAPAGSDFPDTGTTYYGLLMGTNVGELPQEKDMTETYLLLTIV
                     LLIAIVVMMVVLLVLNIKRK"
     gene            complement(23528..23611)
                     /locus_tag="PKM11_05120"
     tRNA            complement(23528..23611)
                     /locus_tag="PKM11_05120"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23573..23575),aa:Leu,seq:cag)
     gene            complement(23648..24190)
                     /locus_tag="PKM11_05125"
     CDS             complement(23648..24190)
                     /locus_tag="PKM11_05125"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HNX47921.1"
                     /translation="MLSGEKVDLVAAERAYVPMYVKWINDPEVTQWLKADPPFSTEME
                     HGWVDKLRREGKMTFTILTKDGRPIGNIGMEDVVWKYRRATIGIMIGEKDHWSKGYGS
                     DAITALLRYCFEELGMRRVDLITDSENHRAQKAYKKCGFQVEGLMRQYRTKNGRVIDD
                     VMMAILANDWFALHPPRGDA"
     gene            complement(24184..24714)
                     /locus_tag="PKM11_05130"
     CDS             complement(24184..24714)
                     /locus_tag="PKM11_05130"
                     /EC_number="2.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HNX47922.1"
                     /translation="MLRGESIGLVPLQTTDELALYKWLNDPRLRKASGRPTWKPAYSL
                     EQVQDLIKERLAQPSRFDLVIVDLENERPMGLVELAHIQPMSDSAQMSMVWGEKGEEE
                     QVLEALVLAASYAFNSQGLHRLWTRLPARDEGTIASFRKVGFKEEGVLRQDHFGDGTW
                     QDSLLLSLLSAEARPC"
     gene            24806..25438
                     /locus_tag="PKM11_05135"
     CDS             24806..25438
                     /locus_tag="PKM11_05135"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HNX47923.1"
                     /translation="MDLKIVLLGPPGSGKGTQTERLVAEFGFTKISTGDLLREAVRNG
                     TELGVKAKGFMDAGKLVPDDLVVGLIREKLKGLKGGVLLDGFPRSLEQAKALDEFFHV
                     ELAVDLEVDQEALIKRLTERRSCRKCNSVFHLEFNPPKKKGVCDKCGDELYQRSDDTE
                     KVVRERFNTYTERTAPLTEYYRKKGVLKSVNGMGAIDDVYKRISAVVRTA"
     gene            25493..25565
                     /locus_tag="PKM11_05140"
     tRNA            25493..25565
                     /locus_tag="PKM11_05140"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25527..25529,aa:Gln,seq:ctg)
     gene            complement(25575..26153)
                     /locus_tag="PKM11_05145"
     CDS             complement(25575..26153)
                     /locus_tag="PKM11_05145"
                     /inference="COORDINATES: protein motif:HMM:NF014010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoU domain-containing protein"
                     /protein_id="HNX47924.1"
                     /translation="MDQLDEMLLELKDSSELMIDLAYSSLLYNNKEIAEEVIQMEEML
                     DELANNIQRLAITRVMQDHDEGKAFTAIKLAAAVEEISDAAMQIAMVAIEEDEPHPVI
                     RLSIKDADTTITLAEIKPASDLVGKSLGKMRLASQSGMWVVAVKRDRKYLYGPDKNAT
                     LEIGDVVIARGPPDAEQYFQDLCSGEERLEEP"
     gene            complement(26153..26803)
                     /locus_tag="PKM11_05150"
     CDS             complement(26153..26803)
                     /locus_tag="PKM11_05150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HNX47925.1"
                     /translation="MYDQGRDQRLDKYDLAHATVRDILTEMKDISEIMVDLAYASIMF
                     DSEEIAEEVKNLEEDMEELSKNIRVKAMLAARTHKEATKLSSLLEVAAASRRISNAAG
                     DIVKLMECEVDKRPFLTFILREAEEKIKRLVLADVSDMVGRQIGELGVESETGMRIIA
                     IKRGKRWIYDPEDETKLKSGDSLIVRGTDDGCEILRSFANGDEKWPVYPDEKEEDD"
     gene            27079..28311
                     /locus_tag="PKM11_05155"
     CDS             27079..28311
                     /locus_tag="PKM11_05155"
                     /inference="COORDINATES: protein motif:HMM:NF013895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HNX47926.1"
                     /translation="MSGVVKTFFSNNKAVFTMGFTALLISSLGDIMAGVTLGFMTNTL
                     ELLPGLMILIPAAIGMRGNIFGALGSRLGTSMHVGTFELSLHKGSILRQNMEASLILT
                     MVVSFLMGFLAKVVSTALGVNSISMQQFIFISVFGGVLAGLVLLVVNVIVANLGFRRN
                     WDIDNISAPLLTAAGDIVTLPMLFLAGILVLNWNGDLATLFFDIMMVAFLVITVYLIY
                     EALYRRDEEARRIFVQSSPVLMICIFLDLGAGLTIEDQITHLVAYPALLVLIPLFLQN
                     CNALGGILTSRMSSLLHMGIMLPGKAPGKVSYENFAIIYIFALWVFTFVSITTHFVCL
                     ALGLASPGLLVMITLGLVAGLVTVTVLNFLSYYVAVTTFMFSLDPDDHSIPVTSSAID
                     FIGSLALMGIIVALGLSL"
BASE COUNT         5894 a         8360 c         8273 g         5834 t
ORIGIN      
        1 tttgtctgac gtttttttca ggccttccat gataggaaaa acacgtctgg ctatatcaat
       61 tttttgacgg taaaaaagtg ctcccgccgg gattcgaacc cgggtcttcg cctaccttcc
      121 accgcttttc agcgatgtcg aaagggcgga atgattggcc ggactacact acgggagcgt
      181 gggttggcgc ttgatatttg actaattact taaacattag tgagaactga attcggccaa
      241 caacctatct ttgccaacca aatcagaccc tccttgatag gatttattaa tcacattatc
      301 tctttcctgc cttcgtggcc gcgaacaagg gtacgagcta ctgctccaag tgcgggaagc
      361 ctttcgtcgg tttgatgata gtaaaggcga tagccgccat ctacgccatc tacttcttcg
      421 ccttgttctt cttcaacctg ctggtcatgg gagacgactg gatgctggca cagctgtcct
      481 tcttggagcc gttctttcct ttcggcgatg agtacatcgc catctccatc gttttactta
      541 taatcggatt accaataatc atggccggca tatacccggg cgtagaaaag atgtacaagg
      601 gcaatggtgc atcggcttgc aaggactgcc gggcgctcat cgccagggaa caggccgacg
      661 cggccgagat ggccagggca aagcaggagg cgcaggcata cgcctacatg gccaaggtcg
      721 atgggctgga gaagggcgat gcctggatcg gcaagctcat caggtcctgg aagctggata
      781 atcccaacaa gatcccggag gagtgcatgc tcgacgatct ggtcatggct cataacatgg
      841 agagggccgg caattacgag aaagcggcgg tcatcctgga gaagtacctg ttctgggaag
      901 aggccggacg cgtgcgccgc cttgacgacc agaagataat caagcacatc accgtggaca
      961 tgaacgcgct gatcaaccag gtgggaaata aaggtcttgc tatcccgtat aaatgctctt
     1021 cctgcggcgc cagcataacc atcgacaagg actccaagca ggatggtctg aagttctgtt
     1081 cctactgcgg aaccgcttac aacgtcgagg acatgaccaa gataatccag ctcgccttgg
     1141 agtgaacgga cgattcgttc cagcagggcc aacgtcttga ccctgttaca ccaatgttat
     1201 atagagggac gagtttaaag gaaacttacc attggaggct tccattgagc aacgaacctt
     1261 acaaccaggg aagtggcgct gagagcgagg agatccttcg cctcccttac ccgaagataa
     1321 aggagggcga aatgttcggg atagcggatc agctgctggg cgcatcccgc atcaagatca
     1381 tgtgcgccga tggaaagtcc cggatggggc gcattcctgg taagatcaag aagaggatgt
     1441 ggatccgcga gggtgacctg gtcatcatcc gcccctggga cttccaggac gacaagtgcg
     1501 acgttcacta ccgctacaca aaaacccaag cgagccatct gagccgcaag aaggttctgc
     1561 cgaagaactt ggacatcttc tgagggataa atgccaaccg aggacaagca aatcctcaag
     1621 ctggaccgca tggtggagaa ggcccgccta acccgctcct tcgaaagctc gcaggaaggc
     1681 cgcaaggtca tggaggaggt cttcgacaac ctcactctcg gcgtgatctt caaattgaca
     1741 tgtgagaagc gcatcgccag cgtcgatttc cccgtgtcca ctggcaagga agggaacgtg
     1801 ttccgggcca ccgcccccga cgggacgttg gtcgcgttga agatataccg aacttccaat
     1861 tccaccttca agaacatcgc caagtacatc gagggcgaca cccgctttaa gggcttaacc
     1921 ggcaacccgc gtaagctcat ctacgcctgg tgcaccaagg agttcaagaa cctgaaccgg
     1981 ctggaacatg ccggggtccg ggtccctcat gctactcgat tcctcaagaa catcatcgtc
     2041 atggactacc tgggcgacca ggtcatggcc gccccgcagc tgcgcaacgt ccgtctggaa
     2101 cagccgcaga aggtgtaccg cgagatcctc cggttcatga agcgggcgtt ccagaaggcc
     2161 aagctggtgc acggcgacct cagcgagtac aacatcctca tgcatgacgg gctgccgtac
     2221 atcatcgacg tcggccaggc catgctgacc gaccacccca acgccatcga gttcctgaag
     2281 cgggacgtga agaacatcaa ccgctacttc cgcaacatcg acgtcaaggt gtggagcgac
     2341 gagaccgtcc tgaaatacgt acagggggtc agagagaaat gaagatcgtc aagattccca
     2401 aggagcgcgt cggcgcgctc atcggccaag gcggcgagac caagaagttc ctggagcaga
     2461 agaccggcat ccggataatc atcgacgccg aggagggcga ggtatcgttc gatgaaagga
     2521 acatccagga tccgctcctt cccttgaaga taatggacat cgtcaaggcc ataggccgcg
     2581 gcttcgcccc tcataaggcg ttccgattgc tggatgacga cgagtacctg gagataatcg
     2641 acatcgacga ttacgtcggg aagggaacga accagctggt gcgcatgcgt tcccgggtca
     2701 taggcaccgg cggcaagacc cgccgcatca tcgaggatct ggtcggggtg cacatctccg
     2761 tctacgggga caccgtcggc atcatcggga actcggtgca gatggtcgtg gcgcgaaacg
     2821 cggtggacat gctattgagc ggcagcgagc acgccacggt gtacaagttc ctggaacgga
     2881 agcgggccga gctgcacatc gccgagatgg gcttcgatct ctgatcattg tccgttgttc
     2941 agcaacgcct tgaggttgcg agggaaaagc gacagctcca gtcccagggg ctccagcctc
     3001 tccataagct tcttggccct cggcccggag aaatcgccct ctaataggta ggacgtgtcg
     3061 tcctcgttga actcggtgca atgcaccatc cagttccgaa ccgtcgcatt cacggggcac
     3121 accttttggc agatcatgca gccgatcaca gcgttatgtg cgccttccag cacgtaatcg
     3181 gggaaggcct tctcgttggg catctcgttg tggaacgtca gacatctctc cgcgtgcaac
     3241 aggaaccggt cctcggcgat ggccttggtc gggcaggcct tgacgcacgc cccgcattcc
     3301 gcgcagcggt ccatgacctt catatcctgc caatcgtccg gcagctcacg gttggtaaaa
     3361 aagctggtca gccggtggaa ggaaccgtac ctcggcacgt aggatatgtt gtttcggccg
     3421 tactccacca ggccggtgcg ggcggccagg gtcttgtgcg gcagtatcgc ccgcatgagg
     3481 tgaacgccgt tgccgtcccc tctttccaga agttccacga tctccatgtc cacgtccacc
     3541 gccctagcgt aggtcggcgg tatgatggtc cgcaccttcc gtccattgac attgaagctg
     3601 acctcgcagg tcggttgtgg taccgacacc acgatcacgc tcttcgcctc cgggaaagag
     3661 accgggacga aatacttgaa ccggaaaagg gactccttgt agagctgctc gtccagcagg
     3721 ccctttctat acagcccttc cacgtcctcc cgcacctcat cgagatgaga gaccgacatg
     3781 gacctggctt cgtatccccg ctcccttagg agcctgagca tcccagtgtt ctcggccatg
     3841 agcttagttc ggaacggcat gcccgacacg ggattaagga cttttccccg ttaacacgcg
     3901 ataatttaat tatacggaaa gggtaggccg gacgaccatg aaggaagttc tcgagcaagc
     3961 cctgaaggcc caggaccgcg acctatgcga tcactgtctg ggccgtctgt tcgcgcacgt
     4021 gggcaccggc actaccaacc tgaagagggg ggaggagcta cgggcgctca tcgacgagga
     4081 ccgctcgtcc cgcggactcg gtcccatgaa tcacgagagg tgctggctat gcgacgagat
     4141 attcgaccag gtcccccgct acgcggaggc catcgatctc aagctgcaag aggtccagtt
     4201 cgacaacttc ctggtcggca cgagagtgga cccggcggtt caggccaagg aggaggagct
     4261 gtggtccata gtcggccagg agcatgccga gcccatcaag tccgagctca accgcgaaat
     4321 aggcaaggcc gttttcgcca tcaacggcaa ggacgtagag ttcaagagcc cgcaggtcgt
     4381 ggcgttggtg gacacccgct tcgcccatgt ggagctggac gtggcgccgc tattccttta
     4441 cggccgctac cgcaaactgt cccgggagat cccccagacc aagtggccct gccggatgtg
     4501 ccagggcaag gggtgccagc gctgcaataa cactggcaag atgtaccaga ccagcgtgca
     4561 ggagcagatc ggggacgtga tcctaccgca cgccaaggcc aaggagcact tcttccacgg
     4621 catgggccgg gaggacatag acgccctgat gctcggcacc gggcggccgt tcgtcatcga
     4681 gatatcatca ccggtggtgc ggaccctgga catcgccgcc ctgcaggaag agatcaacca
     4741 gaaggcccaa gggatggtgg aggtggagca gctccgtctc tcgaaccgag aagaggtacg
     4801 cctggtcaag gactccgccc acgacaagga gtaccgcgtg caggtatcca ttcacggcaa
     4861 agttaataag ggaaaagtgg atgaggtggt tcgcacgttc aacagaaccc gtatcgtcca
     4921 gcggacgccc gttagggtgt ctcacagacg cgcggacctg aaacgcgaac ggtacatcgt
     4981 ctacgtggtc ctggaggatt tccaggatga tcgcatgacg ctgcgcctgc gtaccgagtc
     5041 cggcacatac gtgaaggagt tcgtgcacgg cgaccaggga agaacgctac ccaatctctc
     5101 ggagatgctg ggagtgccct gtaccgtgga cgccctggac gtcatcgggg tcatagataa
     5161 aagcgaggaa tagacatggt aaaagcatcg cacggacaga gagggaaggg caggaacatt
     5221 ctgagaagga gccccagggc tcgtggactt tcccccatca cccacgagtt cgttcagttc
     5281 gacgtaggag agcaggctca catacacctg gaccctagca tcgtcaaggg tgcaccgcac
     5341 ttgcgcttcc acggaaagac cgggacggtc aaggccgctc agggacgcgc ttacgtgctg
     5401 tccgtcaggg acggcgacaa atacaagacc gtagtgagcc ggcctgagca catgcgaaag
     5461 gtcaagaact gacggtgatc caaatgagca aagatcgcta cgtcaccctg gctgaggtca
     5521 aggagatgct ggaggctgag gccgagtctc gggagttcac cccagagcag aggctggcct
     5581 tcgagcatgc caaaggcgcc aagatgagcg ccaagcaggc ccgggagctg aaggggaagc
     5641 tgctcgaact ggagttcgtg ggcgacctca acaacgcaga ggcggtggcg gtcaagataa
     5701 ccgatctcct gcccacccac ttcgacgatg ttcgcctgat cttccagaag gagaggcgga
     5761 taatcgagaa gaagcagggc gagcagatta ttaaattggt gaacgaatac ctttaggctg
     5821 gtgtttcttt ggaggactac gctcacattc tagattatct accgcagggc ctgcccatgg
     5881 ataggggcct cagaaaggaa tcggtagcgt acgccctggg cagcaccgag ctaaagctgt
     5941 tcgagctggt accgaaaccg ggggagatca tctctccagg tgatgtcgtc tacatcggca
     6001 aggacatgga caagcgggac aagatccttc acgtcaagcg tcgcgtaagc ttcgaggagc
     6061 tcaacgccgg ctcccagaac gagcttccct tcgtcatcct ggaggtggtg aaggagaacg
     6121 agatgcacta cgtcaagttc ttcaacgagt cggaggccat cactacccgt taccacgtgc
     6181 tggagcttct acccgggctg ggaaagaaga ccatgctggc gatactggat gagcggaaga
     6241 aagggccgtt caagtccttc gcggacatcg cggcgcgcat tccgaccttc aagcgtcccg
     6301 agaaggtcgt ggccaagcgc atcgagctcg agttggccga ttccacccag aagtaccgcg
     6361 tgttcgtctc ccgctgagat gatcagcatc ggggagctgc gctcccttct ggaacgatac
     6421 ggcgtgcggc cttccaagtc ccggggacag aactacctca tcgaccgccg cgttgccgaa
     6481 cgggaggtgg agtacctcga tatcgccgag aacgatcggg tcctggaggt cggtccaggc
     6541 tttggaattc ttacctccgc gcttttagaa cgcacgtcca agctcaccgc cattgagatc
     6601 gaggaggggg cggtgcgcta tctccgcgac acgttcccgc agatggaggt cgtgcaaggc
     6661 gactttctgg aaacggaccc tccgcagttc gaccttttca tttcgaacgt gccgtacagc
     6721 atctcctcgc cgctgctctt ccacctgctg gatatgaagt tcaagagagc ggtgatcatg
     6781 gtgcagaggg agttcgccga gcgcatggcc gcaccggccg gggatgacga gtattcgcgc
     6841 ctctcggtca acgtgttcta ccgggccgag tgcaagctcc tggagaacgt tcctcgttcc
     6901 cgcttctggc cggagccgga ggtggattcc acggtggtgc tgctcacccc ccgtcctgct
     6961 cccttcccgc tgcgggacga gaagcatttc ctaaggctgg tggacgtgct gttccagcag
     7021 agacggaaga agatcggcac ggtgctcaag cagaagcgca tgcttcccga tgacaggtcc
     7081 ggtataccgt tcctggacga gagagtggag cgtctcaccc cggcccagat cgccgagctt
     7141 tccgattcgt tatcgtccca aagctgaaac gcatcttcat aatcccgccc acttatgtaa
     7201 ttccagggaa tgcgatgggc agcgacggca tcgatatcac ggagattggg aaggtcctgg
     7261 gaacggctgg gcatctggct ttggaaccgc tatgcgtgtt cgagagcgaa ctgaggcccc
     7321 ggaaaggaag gccgttcggg gaggtggacc gctgcatcgc caaggcggtg ctcatgtgcg
     7381 cccaggggaa ggaggaactg ttgtacatcg gtgaggacgc ccgttccggt atttgccctg
     7441 gagggcagtc ctggatgggg ctggccgaaa tggccgaagg attgaaattc ttcatctcca
     7501 ccggttcccc ttccttccgc catggggaag ccgagtacct taagagggac ccggaaatgg
     7561 tccttcgtag caaggcgctc gtcggaagga tacgcccgcc ggagaagtat ctggtggtga
     7621 cgcagtgccg tcacttcagg aaggaggacg gcctgccgag ggcgctcctg ctgttcgtcg
     7681 aggccgagca gctcaggaat ttgctaagcc tgcatcattt cgggacgccg gacgccttca
     7741 cgtcgacctg tgccccctgg gggcccagct gcgcttcgtt cctaacctat cctgccggat
     7801 tggcctccaa ctgcccggac caggccctga tcgtcggacc tgtggaccca acgggcaaca
     7861 gctggatgcc gccgaacctc atgtccctgg gcctgaaggt taaggacgcc gagagaatgg
     7921 tccgggacat accctcctcg tttctctcta gacgccccca ggtggccttc cccgacggtc
     7981 gttaggaacg gttcggccat cctcgggcaa tcattttaac tttaaccacc ttatggaggg
     8041 acggagagac catgcttatc gggatagtag gcaaacccaa cgtaggaaag tccacattct
     8101 tctccgcggc caccatggcc actgcggaga tagcgaacta ccccttcacc accatcaagc
     8161 ccaacaaggg catgggctac gtgcgttcca agtgcccgca cctggacttc aacgtcaaat
     8221 gcactccccg aaactcggcc tgcgagaacg gagtgcgtct ggtgcccatc gagctgctgg
     8281 acgtggccgg actggtgccg gacgcctcgc tgggcaaggg tctgggcaac cagttcctgg
     8341 acgacctgcg tcaggccgac gccttcattc acgtggtcga cgccagcggt tccacggacg
     8401 ccgaggggaa cgccgtcaaa cccggaagcc acgacccggt ggaggacctg cagttcctgg
     8461 agagggagat caaccagtgg atcaaaggca tcatcatgaa agggttcgac aagctggctc
     8521 gcggggcgca tctggaaggt tcaaagatcg atcaggtcat ctacgagcgg ttgaccggac
     8581 tgggtgtcac ggaggtgcag gtctccgcag ccctccggac ctcggagatg ccgcacaaga
     8641 tcattgactg gaaggacgag gacctctacc gtctggctgc caacgtcagg aagatgagca
     8701 agcccatgtt catcgccctg aacaaggcgg acgcggccga ccccgagctg atcaagcggt
     8761 tgagcgcgct tgacggatac atgtccgtcc cgacctgcgc ggaaacggaa ctggcgcttc
     8821 gcagagcggc caaggccggt cttgtgtcgt acgtgccagg ggacaagagc ttcaaggtca
     8881 acgacccctc caagctcaac gccaatcaga agaaggccct ggacttcatg gctcacgtca
     8941 tgtcgatgta cgacggcacc ggggtccaga aatgcctgga ggcggtcact tacaagttgc
     9001 tcgaccagat agtggtctat ccggtggagg acgagacgca cctgaccgac cacgagggtc
     9061 gggtgctgcc ggatgcccac ctccttagga aagggagcaa cgcccgggac ctggcgtaca
     9121 aggtgcacac cgacctgggg gacaatttca taagggccat caatgcccgc acgcatcgcg
     9181 tggtcggcca agaccatgtg ctggagaacg aggacgtgat gaccatagtg gccaagaggt
     9241 agagatgggt gaatgggacg tacgccttct cacggcctcc tattcgaagg gggacaacga
     9301 cagcatagtc gtcgagctgt tcggcaagac gcgcgacggg cggtcgataa ccatgcgcaa
     9361 gaccggcttt cgcccctact tccacgtggc cgccccgccg gaggacgttc tcccctacgt
     9421 gcagggcaag gatgattacc tgggcataga gccgatcgag ctcttcctga tcaacaaggg
     9481 ccgggtccag agctgctcca aggtcatcat caagttcccc tgggccgtgc cgcaatatcg
     9541 gagcgagctc aagcgccagg gcatggaggt cttcgcggcc gacataccgt tccatcatcg
     9601 tttcatctac gacaatgacc ttccggcgtg cttcaccgcc cgcggggagg agatcaaggg
     9661 tgagtacacc accgatctgg tcatcaatct tcgcggcttc accgagatac cgcccttcac
     9721 cccgaagctc aaggtcatga gcttcgacat cgagaactcc atcacggacg agacgatata
     9781 caccatctgc tacgtcatca aggacgaagg cgggataagg gccggagaac ccatcttcgg
     9841 gaccgagaag gagatcatcg agaggttcac cgaggccatc cagatggagg accccgatgt
     9901 catcaccggc tacaacatcg acgggtacga catccccttc atcatggagc gggccaagaa
     9961 gtacggcatc gacgagctga aatggggccg cgaccgttcc aacccccgcc gggtgatgaa
    10021 caagttctgg cgttgcaccg gacgattgat agcggacgcc tggtgggcgg tgaagatcga
    10081 gatcaagccc aagcaggaaa cgctcaacgc cgtatctaag tcgctgctgg gcgaagagaa
    10141 gctggacgtg gacatgaaga tgaaggtcgg ggaggactac gatccccgag ccatcgacaa
    10201 ggaatgggcg aacaaccggg acaaggttct ggcctactgc acgcgcgacg ccgagctggc
    10261 tttgaagata ctgggaaagg tcggacgcat ccggaagggg atggacctgg cggcggtgtc
    10321 ccgcatgccg gtggacgacg tcctgaactc cggttcctcg cagctcatcg acgccatcat
    10381 gatacgagcc gccgaccgtc acgtgccgca ggtggctgtg ccgttgacgg gcaattacga
    10441 cgatgacgag gagaacgcca tcgagggcgg ctacgtgcac gagatctcgc cgggcgtcta
    10501 tcactgggta tgcgtgctgg acttcaagtc catgtatccc agcctgatca tatccaggaa
    10561 catctgcttc accacccgcg atgatgccgg tcccatagta tcgcctctgg gcgtgcactt
    10621 cctgagcaag gagcagcagc ctggaatcct cccgacgatc ctggcggacc tgatgcgccg
    10681 ccgggacgag accaagggat tggcaaagaa ggccaaggac cccgaggagg cgcattatta
    10741 cgacggattg cagggggcca tcaagatact gatgaactcc ttctacggcg tgttcgcatc
    10801 ctccttctac cgcttcaccg accgctccat cggcggcagc ataaccgcct tcgccaggga
    10861 gaccaccaag ggcatcatca aggccctgac ggacgaaggg gtgaacgtca tctactctga
    10921 cacggactcc atcttcgtcc agtcgcccca cgataatctg gagggttccc tggagttcgg
    10981 cagggggctg gccaaccgct tctccaagga gggtggctcc ctggagttcg agaagatcat
    11041 ggagccgctc ttctcgcacg gcaagaagaa gcgctacgtc ggccgcatgg tctggccgaa
    11101 ggaggagctg gtcatccgcg gatacgaggt gcgccgaacg gactccttcg acctgcaatc
    11161 ggaatcgctc atgaccatgt tcgagttcat catggacggt aagacggacg aggcggtgaa
    11221 ggtggcccgc tcctacgtcc aggacaccct ggccgggaag gtcccgctgg agaagctgat
    11281 catctccaag ggctgccgca acttcaagga atacgccaac cccgacgccc aggcgaccgt
    11341 gcagacggcc aagaagctca tggagatggg gtacgagttc gtgccgggga tgaaggtgtc
    11401 ctggatcgtc accaacttcc gcaagaagcc gcaggaggtc caaccctaca tctccggcca
    11461 ggagttcacc tacacccctg attaccgtta ttacgcggag cgtttggcgc aaacgctgtc
    11521 ccgagcgacc gaggtgttcg gctgggggga gaaggacctc ctgagcggca accagcaggc
    11581 caacctcttc gactacggtc ccgagcagga ccggccgaag atcaagctgg agcaggtcaa
    11641 gaagacggac aagaagctca cactggacga ttatttctga tcgtccgtta aggaaatcgt
    11701 ttaaataact ctacattatc agtgggcatc gtagcgagac aagtctcgcc ggatatgtac
    11761 cccgcaaggg gcgaatcccg aagcgccgcc aactgcggca ctggtgatac aaatggtaga
    11821 aaagaaagtc gacgataacg aggacgggcc taggccagtg aacggtaaga gcatgtactc
    11881 ttacatatcc gacgcctggg accggcccga tgcttcttac gtaaaggatc tgatgtggga
    11941 gaggctcatc atctggaggc gggagcccaa tttcatccgc ctcgagagac ccacccgtct
    12001 ggaccgcgcc cgcgctctgg gctacaaggc caagcagggt atcatcatcg tccgcggcca
    12061 cgtccgcagg ggcggcctgc agaagcgcat gggatacaag ggacgccgcg ccaagcgcga
    12121 gggtatgaag aagatcacca tgggcaagag cctgaagcgg atcgccgagg aaagggccgc
    12181 caagcgctac cccaacctcg aggtgctcaa ctcctactgg gtcggcgagg acggcaagaa
    12241 ggtctggttc gagatcatcc tggtggacaa gcaccacccc tcgatcaagg tggacaagaa
    12301 cctgaactgg ctgtgcaaca gtgccaacaa gaaccgggtg ttccgcggca agacctccgc
    12361 cggacgcaag ggtcgcggtc tgcactggaa gggcaagggt gcggagaagg cgcgcccgtc
    12421 cgtcaaggca cacgacaggc agatcaagta ggctaaacgc ctacccttta atctctttca
    12481 aacgcctttc cacttcttca tttcccatcc cgatgagcgg atggtatatc ggaacctcgg
    12541 cgtgcaaggt cctgttctcc tgcagctcgt ccagggacca tccgaccacc aggccgaagg
    12601 ccttgttgac atggacggcc ttgaccgccg gaccgtgcac cttgcggggc tcggggtccc
    12661 agcgctccag ggtgcgcatg gcctcctcgt tctcgaccac gaacagggcg cggcaacccc
    12721 gcttcatcat catccaggcg gccaaggcgt ccctatcgtt cccgatcagc gccaccacct
    12781 tcccctggct gcccataggt aggccgccag gaccgtccag gtactcgctg aacacgtagg
    12841 cccgtttgtc ccgcacctct acgtacacgg tcagatcggg gtgatgcagg tccacccgca
    12901 ctcctctatg cctattggcc tcgaatattt cctcgcccgc ctgggccgca agttgcatgc
    12961 tggtgtactg gtgcactccg ttccggcggg cctccactcg gaacgtggag tcgtccttga
    13021 tcaacggggt ggccacctcc agcgccaggc gtcggatgtc cttgacctcc gaggtgcatt
    13081 gctgaacatg gctaagggat gatattccga acacgcgcct gagcaccgtg gccgcctctt
    13141 ccggtcggtc cgtggtgacg aacaggcgcc cgtactggct ttccacgaag gcctccaaac
    13201 gctcctgggc cagggcggcc atcatgttgt aggtgagcac cttctcgaag taacggcgca
    13261 cccctgggct cttcaatccc atctccgcat acctgaccag cagcaggccc atgtcccttt
    13321 catgttccgc cgggttataa accattctcc cgctagcatt atgtccttct caggtcatcg
    13381 ctgcacgatg gaaccactgg tgctactgct catcgcgctg ctctgcgtga gcgccggcac
    13441 cgtcggggcg ctgatgggga tcggcggcgg gctcatcata attcctctgt tgaccctggg
    13501 tttcggaatt ccgatgcagg aggccatcgg cgccagtctg atcggggtca tcgccacctc
    13561 caccggggcc gccagcaaat acgtcaagca agggcttacc aacatacgtc tcgcgttgtt
    13621 cctggaaatg tccaccacca tcggttcgat agtcggggcc ttgatcgcgg tctacaccga
    13681 ccagaccatc ctgttcctgc tgttctcaat gctactggtg tactcagggt acaccatgct
    13741 ccgccgcacc gagaagctgt tcacgcccga gcaggcggaa gcggaagggc agctggtgga
    13801 cctgtcctgc caatacatgg accccaagga cagctgccag gtgagctatg gcgtcaaggg
    13861 gcaagggaag gggttggcgt acagcagcgt ggccgggctg ctctccgggc tcttaggggt
    13921 gggcggcgga ctggtcaagg tcccggtgat gaacgtgtgc atgtgcgtac cgctgaaggc
    13981 ggccacggcc accagcaact tcatgatcgg ggtcaccgcc ctcaccgggg ccatcatatt
    14041 ctacggtcac gggctactcg acgcctacct ctgcggggcg gtggcgttag ggaccttcgc
    14101 cggggcgtac ctgggaacga ttctcatggc caggtattcg gccaacgaac tgcgcaagtg
    14161 gttctccgtc ctgttgttcc tggtggcggt caccatggtc ctgaaggcct tcggcctgtg
    14221 gggtggtccc tgatgccctc ccagtccacg ctgtgcggcg tggtacggcc gatcctgcgc
    14281 tggggcatgg tcctgagcct catcctgatg ctcataggtc tggcgttggg ggtgatcgcc
    14341 ggagagcagg aggccaccgt ggtccccttg gaaaagatcc cgttccaatt aatggagatg
    14401 gacccggcgg cgttcctgac cttggggatc gtcctgctca tcgccactcc cttggccagg
    14461 gtcatcgggg cgctatgcgt gttcatcagg gagcgcgacc gcaagttcat cttggtgtcc
    14521 atggccgtgc tgctctcggt gttcctagcc gttatcctcg gggcggcctg agcatcgtca
    14581 tccgtggaac cacatagtat atccatagga gccaacaatt ccctgtggac atggccaagg
    14641 accggcagaa ggacgaccgc tggtactatt ctttcctgcc ttacaacata tcgggaggaa
    14701 gcaccaacgc cctgatcccc ctgttcataa ccgagggatt gaagggcacg gtggcccagg
    14761 tgggcatagt cagcgcagcc acttccctgg cctcggtacc tgctggtata ttgtggggga
    14821 acctctcgga cacctccaag cgccgcgtcc ctttcgttct ggcgggcttt ctgggcgtgg
    14881 ccttctccct gatcctcatg gggctgtcgc agagcatatc cgagtactac atcgccaact
    14941 tcatcttcgg cttcctgggg gcggccatcg ccccggtggg cacggtgatg gtgctggagt
    15001 ccttccgcaa ggacgaatgg ccgaaaaggc tcggggattt cagcagggtc gggggcatcg
    15061 gctgggttct cggtctattg ctgggaacga tctggctcgt ggcatttccc tctgacgggg
    15121 acgccgcgtc catgcgggcg ctgttcatat tggccggggt tctaggattc gtatcggtgt
    15181 tcctgggctg gcgtttcatg agggaaccgc tggaaaatct cagtcggcat caggttccca
    15241 ccgtggacgt actgaacgtg ccgtcgtacc tgatggagaa gttgcgcttc atgccgcagc
    15301 gccttctgta cgtcgtggag atgtcgcaga agaaccttcg tctgcgcaat ttcccaacca
    15361 acctccggcg atactacgcg gtggttttcc tggccttcac cggcttcctg tgcttctacg
    15421 tggcgttgcc gacctatctc gcccgccaga tcggaatgag cagcgccgag gtgttggcgg
    15481 tatatctggc cagttccttg gtctccgcct tgatgtattc cagggccggc aggctggtgg
    15541 agcgtctcgg ggggcgcaag gtccagacca tggccttcgg gctgcgggtg ctgatattcc
    15601 cttccttctt cctggtgacc cttctcccgt tggacctggc tgggatattc ttgctgatgt
    15661 gcgtcctcag cggtctcgcc ggaatgtgct gggccttact ggccgtggcc ggcgattcct
    15721 tggtggccaa gatgtcctat cgctcgttcc gcagtcagtc gatgggcatg tactcctcgg
    15781 tgcgcggcgt ttccacgata gtaggttcgc tgttcggcgg tctggtggcc cagtacttcg
    15841 gctacgtggc actgttcgcc atctcctcgc ttttcataat ctgcgcccta ttgctgttgc
    15901 gctcgaccaa cgtggaaggg gaggcggacg accctcgtcc agaagcggct ctagagcagt
    15961 gaggcgatgg tgcgcccaag ctccctggcc ttttcctcct cgcccgggcg aagttcgttg
    16021 ccatccacca cgaaatgctg cggtcccatc agagggcgaa gtccatcctt gaccagcatc
    16081 cgatgcatct tatcggctgc tccggagtgc atgttctcgt agcgggtatc gaaggtcacg
    16141 atggcatgat cgttgccggc gtccttcatg gcgttgcgca gaagggtgtt gaaacggaag
    16201 gaggcgcgcc cccaatgggt cggcgagccg atcacccaca acgggacgcc tatgaagtcc
    16261 tcctcgcctg aaacggattg ccgacgacag gagacctcgt gaccggaccc ggtcagctcc
    16321 tcagctatca gctgcgcgat ccgctcggtg ttgccatact tggtgtcgta gatgaccaga
    16381 atgcgcatcc tatctttccg gagatgcacc ccctccatta cattacttgc tgtggtcgac
    16441 gatgaaagtt ctaaagctta caaaaattaa aataagtcct ttctagtcat caaccagcca
    16501 acgggtccga tgatcatgca tacaaatagg tccgttctgg tcggggaagg ggatggacca
    16561 cggtgagaat gagccttggc accaagataa ggctgggcat ttctttggcc ctcatcgtac
    16621 tggtagtgtt ggcctccaac cctgaagagg tatgggtcgc tctcaaggac atccggtacg
    16681 agctgatttt cctggtcgtg gtgctgtacc tggtgaacct ggtcttcaag gcctaccgct
    16741 ggggcgttct gatgagccac gccgggtacg agatatcctt ccgcaccatc ttcgccgctt
    16801 tctccctatc tcaggccatc aacaacctca tccccgggcg agtggtcggc gagacctccc
    16861 ggataatcga gatgaacacc cgcaaggggg tggcggtcgg aaaagggcta gcctccgtgg
    16921 tcaccgagag gataatggac tttgccttcc tgaccatact gaccgtttcc agcctattgc
    16981 ttcttctggc ggacatagtc gaggagttcc gtggctacct ggtgttcctg gtggtcatga
    17041 tggtgttggc caatctcctg ttcatctacg tcctcgctcg cccaaagctc ctgctcagga
    17101 tgggcgcctg gggcgcccga ctgacctcca aggtcttaaa gggggagaag ggcgccaagc
    17161 tttccgggaa gatgatggac acggtcgtgt ccttcaatga cgctctgcgc ttcaaagggg
    17221 atcacaagag gctgatctgg ccggccgttc ttaccgccat catctgggtc aatgagatag
    17281 tgcggctgta cctgatcata ttggccctgg gcgtggacgt ttcgatggta gcggtcatcg
    17341 cctccgccag cttggcgtcc ctgagcacgg tcgtgcttac cgccggcagc ggcaacgtgc
    17401 tcatgtcatc cgcggtgttc accgccagcg ggttggatcc ccacgtggcg gcgaccgcag
    17461 gtcttttaag tgcgataacc tctatctggc tgtccgtgcc ggtcagcctg ctagccatga
    17521 taatcgacca gcgcgttcgg tcctccccca gcaaggggac cgacaagaac cagaggggat
    17581 taaactgaag tgcaccaccg tcctgatgct caagaacgag gaagggaaca tcgaagcgct
    17641 caccgaggat atcctggcgg tctacgttga ccgaaagata gacggggagg tcctcctcat
    17701 cgatgatggc agcaccgaca gctccggcga gatatgcgat cggctgacca aggtccatcc
    17761 gaacgtcagg gtcgtccatc acgagaagaa cttaggccgt tcgtacgcca tacgtaccgg
    17821 tttccaacag gccctgggcg acgtggtcat aatcatggac gctgaccggc agtatgagcc
    17881 caagcagata cctttgttcc tagcgaagat ggacgagggt ttcgatgtgg tcaccggctg
    17941 gaggcgggag cgcaccgata cgttcatccg gcgcttcatc tcccggacct acaaccgttt
    18001 catcatccgc cgcaagttca aactgcagat caaggaccag aacagcgggt tcaaggcctt
    18061 ccgccgggag aaggcggtgg ccatgggctt cgatcccgag ggctaccagg gccttcaccg
    18121 cttcattctg cccttggccg ccctgaaggg cctgaagatc gccgaggtgc ctatcgttca
    18181 ttacgaccgt ccctcgggca aatcatacat caagttctac accgtaccct tcatcacctt
    18241 gcgtgacttc tccaagttca agaaggacca caaggaggag atagtcgccc tccgccagaa
    18301 aggttaggta ttcttcatgt acggcctggg gaagctcttt gagaaggtcc ttggcaagct
    18361 gaggatcaat actcccgggc gcaagcttct cctttacgcg gcggtcgccc tgctggtcta
    18421 tggctcgatg atcgtcgttg acaacgcctt cctcatgtcg gccatagatc ccgacctcag
    18481 ccatccggac atggatgtgt accgggccag gacccagacc atactggacg gcggcctcct
    18541 gtatcgtgac gtgcacaccg agaccccgcc gataatcaac tatctgctgg tgccggccca
    18601 gcttctggga ggagatcaac acgactgggt gtggagcgcc tacttttcgc tgttcgcctt
    18661 cctgctgtcg gcgatgatgt acctcggcct aaggcacctg gacgagaaca aggcctatct
    18721 ggccggcatg atcattctgc tgtcgccgta caccatcgcc gaatcgggca ccggggagga
    18781 cgagtccata gtggccttca tcttcatact ggcggtggtg ctcatgctca tcaagcgccg
    18841 gagctccgcc tccgccgcca taggcattgg cgtctggacc aagatgtttc ccatattgct
    18901 cttcccggtg cacttcctgc agcagcgcga ttggaggggg cggatcacct ccgtcctctt
    18961 cctggggatg gcaaccggtc tgatcgccct gcctttcgtg atcatgtgct gggatgactt
    19021 ctccttcttt ctgaacttct atttcctggg cgatgaggga aggcctacag ggggtcattc
    19081 catctggcac ttcctttgga tgggtgggat aagcctgccc agcatggtgc agctcgcctt
    19141 gctgggtggg gccatggcct tcgcctacct ctacccatac tacaagaaga tgccagtttg
    19201 gcagagcgtc accctgatgc tcatgacctt cttcatcttc tatcccaagg tgcacggcgg
    19261 gtactggatc atgctggtgg cgctgctctc catctgggcg gtgcaggaca agcggatatg
    19321 ggaccggacc ttcttcgcct tcctgcccat gatactggcc accatgttcg ctcaagggga
    19381 gacgagggcg ccgccggtgg agttctacgg cagctggctg ctagggttct tcctggcgct
    19441 catcggtctc ataatgttca ttgacgccgt acgactagcg ttgaagcagc cggccttcac
    19501 cgacaaggca taggtcagag caggcgcttc cccgcctcgg ctccggagcg gcaatcgtag
    19561 acctcggtga ccttcatgat gatcaatccc ttgcattcca aggtgggctt gcgctccttg
    19621 accatctggt acatcttctc aaagtcagca cctttctcga ccaccttgac gttccctttg
    19681 atcttcaggc aacccggtac gccgaaggtc cacacctgca aggccacgcg agggttctcc
    19741 ttcagattga ccagggtctg atggaagaac tgattaccga tccaaatggt ctccggatcg
    19801 atcaggatgg ccataccgat gggcaccacg ttagggtcgc cgtcccggga ggcggtggcc
    19861 atggcaaaat acttcgttcc tttgaacagc tcctgcatat cgggggttag cgcgaccatg
    19921 cccgtaaatg gccgtgctgg atattaagcg atgtcgggat gctcagacgg tgcggatctt
    19981 ctccacgttc ctggactgta tcagctgaac ttttagggcg ttcccgacag attattctaa
    20041 caactaccgt tggaacttag tttcaacaaa tccttataga gaatcggcat cgttgaccac
    20101 ttacttcctg aacgattctg cccgggtgga catcgatccg tccaggccca tgttcgggaa
    20161 gttgttcaag tagagatcct cgaaggcacc cgatgaaaaa gaaaatgatc gtaccggggg
    20221 aacttacgct agccatcggt ctgacgacgg tctcgatggc cgtccccctg atggtgcgcg
    20281 ccgggttcgg catatccacc atctcctctt tgccttacgc tctcagcctg atattcgata
    20341 ggatatcctt cggcatctgg aacctgctgt tccagatatg ccttctgatg atactactgg
    20401 ccatcacgaa acggttcaaa tggggatatc tggtatcctt cgtactggcc atcgccttca
    20461 gcctggccct ggacctcttc agcgtcacct tatccagtct gcccagtggg ctctggatga
    20521 atatggccta cttcgccatc agctatgtca tgatgtgcgc tggcatatca ttgatggtca
    20581 gctcccaggt ccccttgatg ataaccgacg ccttcatcaa cgacctcacg ctccattttc
    20641 acgtgacgtt caggaggatg aagacgatat tcgacatcgt ctgcctggta ttatccgcga
    20701 cgctagcgct ggcgctcctg ggcgacctgg ccggcgtagg gatcggcacg atcatcatgg
    20761 ccttcataac cggggctgga gtgcaagcgg tgaacaaggt cgtcgcgaaa gcggtgacca
    20821 tcaggccgct catcaagacc ttgggaagaa ttgccaggtg aaatgcggtc ataacgggtc
    20881 gggcgtcaag taataaatag ggtggaccgt ggattacaag ggcatccact aggcccgagc
    20941 gatccccgga gccaagttac attggaagag ttgaccagca tgatccctta ccacaaaatt
    21001 ctgatcccta ccgacggcag cgacaacacc aaggcggcca tagcctacgc tctgaagctg
    21061 gccaaattgg tcggtgcgga ggtcacagcg atcagcgtga atgacaccag caactatgcc
    21121 accgcctccg gcaccgtcgg tccggacgtc acctcgtcgt tgtaccagct ctgcgaggac
    21181 gccgtccgat atgtggtgga ggagggtgcc agatcagggg taaccgttca taccaacatc
    21241 atcaacggca atccggccag ggatatagtc gaagcttcca aggcccacga cctggtggtc
    21301 atggggtcgg tcggccgcac cggggtggcc cacctgatat tagggagcgt ggctcagaag
    21361 gtggtaagga tggcggcctg cccggtactg gtggttcgca acgccaggcc cgagagcgac
    21421 cttaccatct gccggaagtt gctgataccc acggacggga gcgagaacac cacgatcgcc
    21481 ataaggcacg gcttggagct tgccaaggca ttcaatgccc aggtcaccgc ccttagtgtc
    21541 agcctcgcca aggatcccga ccagatcagc aatatggccg tggaacaggt ggccgaggaa
    21601 ggtcgcaaga tgggtctgaa ggtgatcggc tcggtggttc ccggctctcc tcccgaggag
    21661 atagtcaagg cgtcctttga ccacgacctg atagtgatgg gcactgccgg acgcaccggt
    21721 ctggcgcatc tccgtctggg cagcgtggcc gagcacacca taaggggatc ggcatgcccg
    21781 gtactggtgg tcagggcatc ggtcgaccgc ccggcgatct gaatggacaa ggctcccgcc
    21841 atcaaaggcg aacggtataa atccccttca agggcgtaat catctcctag tcaaggtgaa
    21901 acgcgatggt ggacgctcat cccaggaccg tttatgtgcc gttattgata accgcccttc
    21961 tccttctatc ttcatttctc gtactggtgc cgggagaggt cgccgccctg tcggaaggtg
    22021 attacgagta cgagctcacc ggcgtcccag ccgtggcggc catcaccaag tacaccgggg
    22081 ccgggggagc ggtcatcatt ccggccacct taggtggtta cgccaccacc atcattcgtc
    22141 atgacgcgtt caactacggc aatgggattc atgtaacatc ggtgataata ccaagtagcg
    22201 ttcataccgt cgagaactac gccttcgcca actgcgaaga tctggagaag gttttgatcg
    22261 gttccggtgt ctcctccata ggcgacgcca cgttcatcaa ttgccacaac ctgaatacca
    22321 tattggtcca cgatagcaat ctcttctatt ccagcctgga cgacatactt tacaataaaa
    22381 cgatgaccgc tctgatcaaa tgcccctcgg ccaaggccgg ggacgtaacg ataccggaca
    22441 ccgtgacctc tttgcgttat ggcagctttg acgattgccg gtccatcgag aacctggtca
    22501 taggcagcgg ggtgaccgag atcggtcgat acatgttcga gagcgtcgat gacctgaaga
    22561 ccgtgacctt ctccgccgga agctcgctac acaccatagg cgagagggca ttctccgcat
    22621 gcgagaacct ggagtccttt gacgcgcctt cgggattgtt gaccatcgaa aacgaggcat
    22681 tccagagatg taaatcactg gtcgtcttcg accttccgtc cggtctggag agcgtaggtc
    22741 ctggggcttt tgcggggtgt gagtcattgg tcaacatgac cgtacccgct agtgtgatgg
    22801 aaatcggcct atacgccttt tccggatgca agagcatagc ttggttcgat gttgaatccg
    22861 agaatgaaaa tttctgcagt attgacggcg ttctgtacaa caagacggcc accgttctta
    22921 tgcaatgccc cggcggcaag accggcaacc tcaccatccc ggacagcgtg atcgagatcg
    22981 ccatgtactc cgtggccggg tgcatcatca ccggtgcgag gatagggaac ggggtggaaa
    23041 aaataggcgt ctattccttc tacgcgtgca ccaaattgaa ggccgtggag atgggcgaca
    23101 gcgtggagat aatcggcggc ggcgccttct acggctgcaa gctcctgaaa tccattgagg
    23161 tcccggccac cgtgaccgag atacaggtcc aggccttcgc cgaatgcctc acattgaaca
    23221 acatcacctt cctcggctct tccgcccaga tcgaggtggg agcggattgg atactgcaca
    23281 cctcgtggga actgcaaggc cacgccccgg ccggttccga tttccccgat accggaacga
    23341 cgtactatgg tctgctcatg ggaaccaacg tcggtgagct gccgcaggag aaggacatga
    23401 ccgagacata ccttctgctg acgatcgtcc tgctcattgc catcgttgtg atgatggtcg
    23461 tattgctggt gttgaacatc aaacgaaaat gaaggagctg atttagggat atcagaaggg
    23521 aaggaagtgc aggggaaggg atttgaaccc tcggaccact aaggactaga ccctgaatct
    23581 agcgccgttg gccaggcttg gctacccctg cctaggatga ggccaatgat attttgctac
    23641 aaatacctta tgcatctcct ctgggagggt gcagggcgaa ccaatcgttg gccagtatgg
    23701 ccatcatcac gtcgtctatg acgcgtccgt tctttgtccg gtactgtctc atcagtccct
    23761 cgacctggaa accacatttc ttgtaagcct tctgcgcccg gtgattctca gaatcggtta
    23821 tgaggtcgac ccgccgcatg cccagctcct cgaagcagta gcgtaacagc gcggtgatgg
    23881 cgtcgctgcc ataacccttg ctccagtggt ccttctcgcc gatcatgatc cctatggtcg
    23941 cccggcggta cttccagacc acgtcctcca tgccgatgtt gcctatcggc cggccgtcct
    24001 tggtcaggat ggtgaaggtc atcttgccct cgcggcgcag cttgtccacc catccatgct
    24061 ccatctcggt gctgaacggg gggtcggcct tcagccattg ggtaacctcc gggtcgttta
    24121 tccacttcac gtacattgga acgtacgcgc gttcggcggc caccaggtcc accttctccc
    24181 cgctcaacat ggccgagcct ccgctgagag caatgacagc agcagcgagt cctgccaagt
    24241 tccgtcaccg aaatggtcct gacgcagaac cccttcctcc ttgaatccca ccttgcggaa
    24301 ggaagcgatg gtcccctcgt ctcgagcggg cagcctggtc cacaggcggt gcaatccctg
    24361 ggagttgaag gcgtaggagg cagccaagac cagggcctcc aggacctgct cctcttcgcc
    24421 cttctctccc cataccatgg acatctgcgc ggaatcgctc atcggttgga tgtgcgccag
    24481 ttcgacaagt cccatgggcc gttcgttctc cagatccacg atgaccaggt cgaagcggga
    24541 gggctgagcc aatcgttcct taataaggtc ctgcacctgc tccaggctgt aggcgggctt
    24601 ccaggtggga cggccggagg ccttgcgcaa ccgggggtcg ttcagccact tgtacagcgc
    24661 cagctcgtcc gtggtctgca agggcaccaa cccgatcgat tcccctctaa gcatgcggat
    24721 ttgattgcca gactagaaca taatcctatt gctgtcggga cgaaaaaatc gcaaagatga
    24781 tttatgggga ggggcatggc cgggcatgga cctgaagatc gtgcttttgg gacctccggg
    24841 atcgggcaag ggaacgcaga ccgagaggct ggtagcagag ttcggtttta ccaagatctc
    24901 caccggggac ctgctgcgcg aagcggtacg caacggaact gagcttggcg tcaaggccaa
    24961 gggattcatg gacgccggaa agctggtgcc tgacgacctg gtggtcggac tgatcaggga
    25021 gaagctgaag ggactgaagg gcggcgtgct gctcgacggg ttcccccgtt ccctggagca
    25081 ggccaaggcc cttgacgagt tcttccacgt cgaactggcc gtcgacctgg aggtggacca
    25141 ggaggctctg atcaagcgcc tcaccgagag aaggtcctgc cggaaatgca actccgtgtt
    25201 ccatctggag ttcaacccgc ccaaaaagaa gggagtttgc gacaagtgcg gtgatgaact
    25261 ttaccagaga agcgacgaca ccgagaaggt ggttcgtgaa cgcttcaata cctacaccga
    25321 gcgcaccgcg ccacttaccg agtactaccg caagaagggc gtgctcaaat cggtcaacgg
    25381 catgggcgcc atcgacgacg tgtacaaacg catatcggcg gtcgtcagga ccgcctgaac
    25441 catcttcctg cgaaaaggtt aagaccaggg attaattacc accgttccgc acagccccgt
    25501 agtgtagcgg tcaatcatgc gggattctgg atcctgcgac ggcagttcga atctgcccgg
    25561 ggctactcct tatcctacgg ttcttccaga cgttcctctc cagagcacag gtcctggaag
    25621 tattgctcgg cgtccggcgg tccgcgggcg atgaccacgt ccccgatctc cagggtagcg
    25681 ttcttgtccg gtccgtagag gtacttgcgg tccctcttca cggccacgac ccacatcccg
    25741 ctctggctgg ccaacctcat cttgcccagg ctctttccga ccaggtccga ggccggcttg
    25801 atctcggcca gggttatcgt ggtatcggcg tccttgatgc tcaggcggat caccgggtgc
    25861 ggttcgtcct cctctatggc caccatggcg atctgcatcg ccgcgtcgga tatctcttcc
    25921 acggcagctg ccagcttgat ggcggtgaac gccttccctt cgtcatggtc ctgcatcacc
    25981 cgagttatgg ccagacgctg gatgttgttg gccagttcgt ccaacatctc ctccatctgg
    26041 atcacctctt cggcgatctc cttgttgttg tacagcaagg acgaataggc caggtcgatc
    26101 atcagttcgg aggagtcctt gagctccaac agcatctcgt ccaactggtc catcagtcgt
    26161 cctcctcttt ttcgtccgga tataccggcc acttctcatc gccattggcg aaggaacgca
    26221 ggatctcaca tccgtcgtcg gtgccgcgta cgatcaagct gtccccggac ttgagcttgg
    26281 tctcatcctc cgggtcatag atccagcgtt tcccgcgttt gatggcgatg atgcgcattc
    26341 ccgtttccga ttccactccc agctcgccta tctggcgccc gaccatgtcc gaaacgtccg
    26401 ccaggaccag gcgtttgatc ttctcttccg cctccctgag gatgaaggtc aggaaaggcc
    26461 gcttgtccac ctcgcactcc atgagcttga cgatgtcccc ggcggcgttc gagatgcgtc
    26521 tggaggcggc ggccacctcc aacaaggacg acagcttggt ggcctccttg tgggtgcgcg
    26581 cggcgagcat ggccttcact cgaatgttct tgctcagctc ctccatgtcc tcctcgaggt
    26641 tcttgacctc ctcggcgatc tcctcgctgt cgaacatgat ggatgcgtag gccaggtcga
    26701 ccatgatctc cgagatgtcc ttcatctcgg tgagtatgtc cctgaccgtg gcgtgagcca
    26761 gatcgtattt gtccagacgt tgatcccttc cctggtcata cataaaaaga acacctgcgt
    26821 cgattcacag cgatggacct ccagctattg cggaagttgt acaaggatat cgctcgtgac
    26881 atctcagttg gcctcacgga accaccagcc tcatagggcc tggcggaccc gtcattcctt
    26941 ccttatgagg ttagccatat atcatcgtta cgaattcgaa tggaaaatgg gcctacctgg
    27001 gcgcccagcg agggccatct ggtcacgaac acgacttaat attaataggg tcaaatccta
    27061 cctctagcgg gtgctaggat gagcggggtt gtgaagactt tcttctccaa caataaagcg
    27121 gtcttcacca tgggtttcac cgctcttctg atctcatcgc tcggcgacat aatggccggg
    27181 gtcacgcttg gtttcatgac caacacccta gagctccttc caggactaat gatcctcata
    27241 ccggcggcca tcggtatgcg ggggaacata ttcggggcgc tagggagccg tctgggaacg
    27301 tccatgcacg tgggtacctt cgagctatcc ctgcacaaag ggagcatact ccgccagaac
    27361 atggaagcgt cgctcatact gaccatggtg gtttcgttcc tcatgggctt cctggccaag
    27421 gtggtctcca ccgccttggg cgtcaacagc atcagcatgc agcagttcat tttcatctcc
    27481 gtcttcggtg gggtcctggc cggattggtg ctcctggtcg tcaacgtgat agtggccaat
    27541 ctaggcttcc ggcgcaactg ggacatcgac aacataagcg cgccgttgct caccgccgcc
    27601 ggagatatcg tcaccctgcc gatgctcttc ttggccggca tcctggtgct taactggaac
    27661 ggtgacctgg cgacgctgtt cttcgacata atgatggtag cgttcctggt catcacggtg
    27721 tacctgatct acgaggcgct gtaccggaga gatgaggagg ccagacgcat attcgtgcag
    27781 agctcccccg ttctgatgat ctgcatcttc ctggacctgg gggctggtct gaccatcgag
    27841 gaccagatca cccacctggt cgcctatccc gcgctactgg tgctcattcc cctcttcctg
    27901 cagaactgca acgctctcgg cggcatactg acatcgcgca tgtcctcgct cctgcacatg
    27961 ggtatcatgc ttcctgggaa ggcgcccgga aaggtcagct acgagaactt cgccatcatc
    28021 tacatcttcg ccctttgggt gttcaccttc gtcagcatca ccacccactt cgtctgccta
    28081 gccctgggcc tggcgtcccc cggtctgctc gtcatgatca ccctcggcct ggtggccggg
    28141 ctggtgaccg tcaccgtcct gaacttcctg tcctattacg tagcggtgac cacattcatg
    28201 ttctccctgg acccggacga ccacagcatc ccggtgacct catcggccat cgatttcata
    28261 ggctcgctgg cgctgatggg tataatcgtg gcgctgggcc tttcgctttg atttggcaca
    28321 acttaatatg ctatggaatg ttccctaatt attcctgagg t
//
LOCUS       DAOPZI010000020        26469 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1817_length_26469_cov_11.216514, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000020 DAOPZI010000000
VERSION     DAOPZI010000020.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 26469)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 26469)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26469
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1817_length_26469_cov_11.216514"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..510
                     /locus_tag="PKM11_05160"
     CDS             <1..510
                     /locus_tag="PKM11_05160"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47927.1"
                     /translation="KDAYAAAHSAEIINRTGMGDVSGIMRGGIELRKKPGLPPIGHVD
                     RMNGNMDLVLAVVGPSIPTAEMLSDRERLEKINSVGSRCVDSLLKEPTLENFFRLSNE
                     FMDGSGLATPEIRRAVWEAKKWGWASQAMIGNSIFATGPDLELLQEALTQFGDVYRCS
                     VDKKGPRLL"
     gene            complement(511..804)
                     /locus_tag="PKM11_05165"
     CDS             complement(511..804)
                     /locus_tag="PKM11_05165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF357 domain-containing protein"
                     /protein_id="HNX47928.1"
                     /translation="MRDTISQEHLERYLSITKRALEKVTISAPERSFNRKLADSFLEM
                     ARTYFSDAKHFAEQGDYVNAFASVNYAHGWLDCGARIGLFDVGQDDQLFTLYE"
     gene            complement(806..>1531)
                     /locus_tag="PKM11_05170"
     CDS             complement(806..>1531)
                     /locus_tag="PKM11_05170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX47929.1"
                     /translation="TIKNGKVYLNALRKAIDGLKAVKKDYGLKEIIAMLESDEDANNQ
                     TLIAELAYLNEVNIFAPQGTKIDELISPGKTTIINLKGTPPDIQELIVTRLATAMFEL
                     RKLGKVPPMMMIAEEAHNFCPQQGVTSCSKIFRTIAAEGRKFGLGLTIISQRAAKIDK
                     NVLSQCNTQMILKVTNPNDLKAIVSSVEGLQEGMDQEIQRLPIGVALIMGGNIQMPLF
                     VEVRPRQSRHGGESVEIIPSKRL"
     assembly_gap    1532..1631
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1632..2164)
                     /locus_tag="PKM11_05175"
     CDS             complement(<1632..2164)
                     /locus_tag="PKM11_05175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAS-barrel domain-containing protein"
                     /protein_id="HNX47930.1"
                     /translation="MQTNSISESSGKAVLPSEEEDEVPVEEEILDDNVEDVGTPDEVV
                     VHREREPSKHTLEDEKYGHLDGVGMIYGNVGATSFHLRVLGDLQKMDYIQVIHQSHGW
                     VLGQVADMERKTDLTLERAKRLSEGMDVEIDEIVIAQITILGYRDERKLLQVPRSPFK
                     AGDMVYRAKDQLIKDVIG"
     gene            2307..3161
                     /locus_tag="PKM11_05180"
     CDS             2307..3161
                     /locus_tag="PKM11_05180"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HNX47931.1"
                     /translation="MIVIGGSASSNLAKDLAKQLNAEYVQAVNKVFPDGEIYTRIERE
                     SLSGEVVIVQNSYPNEKLVELLLLQDAARGLGAEKVTCVIPYFGYARQDERFNRGEPL
                     SARVMVEHIQMKADKVILVDIHNPEIMDWFTKAKVKDVHAAPCVGDFFKEFGVDLVLA
                     PDEGALKRAGWVAEKLGVDWDYLVKTRLSGTHVHMTPKNIDAKDRKVLIVDDIISTGG
                     TIVAATEELKRLGARTVMAACTHGLFVGNALDNLKKHVDKLACANTLESEVSQISVAP
                     EVAKAILE"
     gene            3225..4622
                     /gene="proS"
                     /locus_tag="PKM11_05185"
     CDS             3225..4622
                     /gene="proS"
                     /locus_tag="PKM11_05185"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HNX47932.1"
                     /translation="MRKQEDFSEWYNEIVELANLTDKRYPIKGMNVWTPYGWKIMRFI
                     DTYIREECDATDHDEVCFPLLIPETEFKKEKDHIKGFDAEVYWVTHAGLNELDVRLLL
                     RPTSETAMYPIFALWVRSHTDLPLKTYQLVNTFRYETKQTRAFIRVREIHFFESHTCH
                     VDEADAQLQVEEDFVILENIMKHLCLPYFLLRRTEWDKFPGAFYTVGVDTLLPDGRSL
                     QLGSIHHYRENFSRPFNITYEDEKGEHKFAHQTTFGMSERLVGAVVAVHGDDKGLVLP
                     PDISPFQVVLIPILAKGNVEKVAEECQKLKQELTAAGIRVKLDDSDERPGSKFHNWEI
                     RGVPLRLEMGMRDIEGGKVAYARRDSGTKGSLDRATVVSQVRDTLNQISDDMRAKALA
                     ASNGAIQDLDSLDKVPEKVVRFGWCGEEECGRKFEERTGLKMLGSPYNKEDYHGKCIV
                     CAKAVENPTYAARSM"
     gene            complement(4623..5525)
                     /locus_tag="PKM11_05190"
     CDS             complement(4623..5525)
                     /locus_tag="PKM11_05190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47933.1"
                     /translation="MKKLGSWFLPHLMGLLIMFEGVALVVLAREIELVDALVMDQMMT
                     MALGAVLLVLGLLLFIPLFPQLRRISERLMKRLQVMAAIAVLAISLVFLVMASPATIE
                     DFGGIGKRWVALAAGQLFLLGVLAFVYLYYEPLANRRLAWLEWLGMFSACLVMTEGVV
                     IFGMRGDLNVHGELKAEPTFMIMIGVVLAVLGLLEVVVFNRRREGQSERTLEILDWVV
                     MAVSVTIGALGLFALYITTSMTLDGMNYGYQWLLMAGMVLALLAPLLNYTQTVVAGRE
                     GWNMDIGLIVTIILLVAIPFAVIL"
     gene            complement(5582..5788)
                     /locus_tag="PKM11_05195"
     CDS             complement(5582..5788)
                     /locus_tag="PKM11_05195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47934.1"
                     /translation="MAEQAYPKKAVTIFSLLLVVAAVLFYWAWGVTYGSWNIFAADNM
                     GVYSIFIILLGLGVFGLLLAKYKQ"
     gene            complement(5901..6575)
                     /locus_tag="PKM11_05200"
     CDS             complement(5901..6575)
                     /locus_tag="PKM11_05200"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47935.1"
                     /translation="MSDEIPSNTDVLAGITKGLLEHAEEKALAWVERFRNHEIVFVED
                     SDTIDRVKKQRKSPEWKILSDVLKDKKLRLLAQMGLALRELENDQERTQSLRNKIHHR
                     YGRDGLHIAEAVQNNIISNFIGLESPNIGEPVDLTIRVENLLNNIEKYIVFIGPEDKE
                     EVLVRRVCIRLDADVPDTLILFGAYKAKRVAISVRGKIEKAFPSYATSSIETKIKIII
                     FINRLN"
     gene            complement(6585..6827)
                     /locus_tag="PKM11_05205"
     CDS             complement(6585..6827)
                     /locus_tag="PKM11_05205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47936.1"
                     /translation="MEMLSLKNEPIELKIAILEKMGYSSDGTFIYDSSGDMIIDPYID
                     EAVRIDNMVILQGSEIILDSNPLSFAGYFEDHGEIF"
     gene            7132..7557
                     /locus_tag="PKM11_05210"
     CDS             7132..7557
                     /locus_tag="PKM11_05210"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47937.1"
                     /translation="MELDLWIPIIIWLAIGAGIAFYLYRLMDKEGKVEVIWVVIGFLL
                     SVLGLMAFIGARSMKEKDRDKAVDPKSYQPPEYKLKEEAPKEKAPEEKTPVPAPEPTP
                     EPKKKEVKQIEGIPRCPECGSAISSSDVRCRDCGAKLKD"
     gene            7594..8355
                     /locus_tag="PKM11_05215"
     CDS             7594..8355
                     /locus_tag="PKM11_05215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N1)-methyltransferase"
                     /protein_id="HNX47938.1"
                     /translation="MLPEGSLIYLLDEKGKRTWLVLNKGMLKLGAMGVVDGDKLLAAE
                     DGSELTLAGKRFWILVPGASEMMTSVERGAQVITPKDAATILLELNVKSGDTVLEAGV
                     GSAALTIALLNQVRPWGKVVSMEIRPEFAEKGKRNVDKAGLADAWRLEIGDVRKDRLD
                     ILADAAVLDMPDPWDALDNVSSMLRNGGRFCSYVPNTNQLEEIVRKLRNKGFVEIRSY
                     ENMQREMVVHEMGVRPSYETLGHTGYLVFARKVSV"
     gene            8401..9048
                     /locus_tag="PKM11_05220"
     CDS             8401..9048
                     /locus_tag="PKM11_05220"
                     /inference="COORDINATES: protein motif:HMM:TIGR00427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter"
                     /protein_id="HNX47939.1"
                     /translation="MDLAFAITAFASIFAIMNPVGNIPVFVAITEGYTPELKRKVINK
                     VCIVAGGILIIFALFGNYIFDIYGITIPAFKIAGGALLFSIAFTMTKGQLTKAKMTDE
                     EEKEATEKEEVGVVPLGIPLFAGPGAITTVMIYVSYALDSPDPTVNFGFIFLGILVTV
                     VISFFLLRYADPLFNRMGKSGTMAFTRIMGLLLAAMAVEFILSGTFEAVSHYWGI"
     gene            9101..9340
                     /gene="purS"
                     /locus_tag="PKM11_05225"
     CDS             9101..9340
                     /gene="purS"
                     /locus_tag="PKM11_05225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HNX47940.1"
                     /translation="MVVAEIRIELKPGVADPEGKNTKKALELLGFKDIKGVRSIKMFE
                     IEMDADPAVARKECEEMCRKLLANPVIQKFRVDLR"
     gene            9346..11658
                     /gene="purL"
                     /locus_tag="PKM11_05230"
     CDS             9346..11658
                     /gene="purL"
                     /locus_tag="PKM11_05230"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HNX47941.1"
                     /translation="MPLDHLFFKRDVPFHLVEIDLAKAKDDELKVLSKDMGLSLSLDE
                     MKRIRDHFVSLKRRPTDVELESIAQAWSEHCCYKSSKVILREHIFGIDNGKVLSRGDA
                     GVMEFDDEYGYALRIESHNHPSAIEPYGGAATGIGGIVRDVLCMGAQPIALIDPLFFG
                     PIDYKGELPAGSKTPKYLVSGVVAGIRDYGNRIGIPTVCGGLYFDESYLGNCLVNVGC
                     VGIVKKKDLRNNAVGGVGDYLILCGGRTGRDGIHGVTFASAELSSKSEDESRGAVQLG
                     DPITKEPLIHACLEVNSLGLINGMKDLGGGGLSCVVGEMALSGGCGAEVDLDKVPLKE
                     SGLAPWEVWVSESQERMMLAASEENVERILDLFALWDVDATVIGKVVPGRQVTLKWMD
                     VQVFQVDLEFLTKGPEYCRPCKIETPSKTIKEVRPLLPDTKTVLLELLADPNIASKEW
                     VFRMYDHEVRGGTVVKPSSGVMNKGGPSDATVIKPLPDRERGLALAIGVNPWFCGLDA
                     YRGGMASIDEACRNIIAVGGYPDSFTDCLNFGNPEKPERLGELKQAVAGMGDLARFLN
                     LPVPSGNVSLYNETARGSVLPTPTVLGLGIVEDVRKCVTTDLKKEGNLLYLVGETKEE
                     FGGSAVYRRYGGKGGEVPEVIPERLKQSMDEMHAVMKKDLIRSCHDVSDGGIAVAVAE
                     MCLGGNIGADVSTGYDRWYLFSESSTRWIVEIEPSNKKEFLSSMTVPVLELGKVGGKS
                     LRIKDRCMLVNLSLSEMRKAWSGALPKLMG"
     gene            11663..12478
                     /gene="purQ"
                     /locus_tag="PKM11_05235"
     CDS             11663..12478
                     /gene="purQ"
                     /locus_tag="PKM11_05235"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HNX47942.1"
                     /translation="MKDVKVCVLRIEGTNCEDEAAQAFASVGASPEKVHLKQLLGQCP
                     SDLRRDLGSYDILMLPGGFSAGDYVRAGAIFAARMKSGLKNEIVRFVEDGKPVLGVCN
                     GFQILVELGLLPAMDETMSEAPEAALYTNDSGRFECRPTLLRMEKRQRSVFTSNIPNG
                     SVLMYPSAHAEGKLMFPHSRQSKMLKRLLDNDQVMFRYVDPEGEYAGYPWCPNGSLYN
                     IAGICNPAGNVLGMMPHPERVLKRETHPDWTRAKRKEDGDGLSIFRSAVKSVK"
     gene            complement(12479..13153)
                     /locus_tag="PKM11_05240"
     CDS             complement(12479..13153)
                     /locus_tag="PKM11_05240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF120 domain-containing protein"
                     /protein_id="HNX47943.1"
                     /translation="MQPENDEKFVTALRRIALMGGLHDYVALSSRELGDMLDMSQQSA
                     SKRILELLDGKLIERDLGARRQRIRITSKGSDMLRKEYLEYQKIFEMKDELVIKGTVV
                     EGMGEGQYYVTQPGYMEQFVEKLGFKPYEGTLNVKLLTTEHHKLDTLRNGRTIDIKGF
                     ERNGRTFGDVHCIPASIQNIECAVVLPRRSHYEDVLEVVCKFHLRRTLGLEDGDQIEV
                     RIHLNL"
     gene            13280..>13707
                     /locus_tag="PKM11_05245"
     CDS             13280..>13707
                     /locus_tag="PKM11_05245"
                     /inference="COORDINATES: protein motif:HMM:NF021398.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2099 family protein"
                     /protein_id="HNX47944.1"
                     /translation="MTKDRHVMEVLGLSRVVVENGVVVDVSEPRVEFCPLFYKQRGIE
                     KLTKESIRGNVEFRIRDFGIFTERREMRMKDFLSFGISEIMSMCVIKGILDCSVCVCD
                     GSGTAVVEDPEIIQGIGGRISGMVETTPLQNVINAIGRDRV"
     assembly_gap    13708..13807
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(13958..14311)
                     /locus_tag="PKM11_05250"
     CDS             complement(13958..14311)
                     /locus_tag="PKM11_05250"
                     /inference="COORDINATES: protein motif:HMM:NF037434.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twitching motility protein PilT"
                     /protein_id="HNX47945.1"
                     /translation="MQKVVLDTNALLMPFEFKMNLDLELANLFGEFEAYVPGPVIGEL
                     KRSDSKHSKAALMLAGKYIRYETSTQGDAGVMEVAKALGAMVVTNDYILRRKMRQEGI
                     RAIFLRSRKRLVIEE"
     gene            complement(14318..15547)
                     /locus_tag="PKM11_05255"
     CDS             complement(14318..15547)
                     /locus_tag="PKM11_05255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 subunit
                     gamma"
                     /protein_id="HNX47946.1"
                     /translation="MKVSRQPEVNIGMIGHVDHGKTTLTKALSGDWTDRHSEEIKRGI
                     SIRLGYADVSFYKCKKCEETYSNSTTCKVCGGEAEFVRSVSFVDAPGHETLMATMLSG
                     AAMMEGALLLVAANEECPQPQTKEHLMALSIIGVENIIIVQNKIDIVTRDEALANYNQ
                     IKKFVKGTIAENAPIIPVSAHHDVNIDKLIDAIQKYIPTRKHDEKKAAKLFVARSFDI
                     NQPGMDINELKGGVLGGTLMQGVLKVGDEVEISPGRKVEQPGGKFTWETITTTIESLH
                     TGGGPVNKIRPGGLVAIGTKLDPSFTKSDGLTGRVVGKPGTLPEVHFKFKMKTHLLER
                     VVGTTDDMVVENIKTNEPLMLSIGTATTVGLVTSARGDQSEVALKIPVCAEIGQRVAV
                     SRKIANKWRLIGYGIVE"
     gene            complement(15547..15942)
                     /locus_tag="PKM11_05260"
     CDS             complement(15547..15942)
                     /locus_tag="PKM11_05260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6e"
                     /protein_id="HNX47947.1"
                     /translation="MVEFKAVVNDMKSGKSYNVPVSGHHANSLIGKKIGDTIDGIFVG
                     LPGYKLTITGGSDKDGFAMRKDLPGPRRKKLLLTCSTGFYTTEGGLRRRKSVRGHSVA
                     TDTVQINMKIVSQGPKPVEELVPKKEEKK"
     gene            complement(16034..17233)
                     /locus_tag="PKM11_05265"
     CDS             complement(16034..17233)
                     /locus_tag="PKM11_05265"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR02032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HNX47948.1"
                     /translation="MKEYDVLVVGAGPAGSGAARASALAGVRTLMVDKKKEIGTPVQC
                     GEVIGLELVKRSGMRIPENAIVARHQFTRFVLGREVVIDNAEAYWHAVTVERKIFDKH
                     LAFRAARAGADVQADTKLLSVKMAGDTVKSCLLSHQGEEVELSPKAIVAADGVHSTLS
                     KELKAEFFSPQDVARGVEFELVAKKDIPQCMQIFIEQEIGLGYGWIIPKGKRKANVGL
                     GLVGVNASRRSFLEDWITGHPVVSRYFDVDKVLEVKIGDAPVPGFLGGPVRGNVLFCG
                     DAAGQTLAFVGEGIMPSYICGSLAGKHAAMLSQGKGQRYEEELVESMADQLMMGAVLR
                     DTLVELWSSDGLDGRMRSLLSGAVMNELVSPDDMMHSLNALEDDPLRAFKGLVKGSGR
                     DIKVKRC"
     gene            complement(17235..18266)
                     /locus_tag="PKM11_05270"
     CDS             complement(17235..18266)
                     /locus_tag="PKM11_05270"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF013646.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HNX47949.1"
                     /translation="MIIGSGPAGAAAAFFLSYLSDGKLSVLSLEKLDRNYDRYHRMCG
                     EALSTKAFKELAPLEPHAVQFQIRRAVEHWPGEVVIETEADGVIVDRPELLRHMLQRA
                     KKEGGHSECAAAVDVTKRGDDLLVRTRDGREFSAKYLVGADGWNSLVRRTIFQGGPRL
                     LWAEQFITSGTMDRDAMHFFYDQRYQGGYRWEFPHVSGKRVGFTRGADELPEFLERQG
                     RPIPYGYDKVVEGNACLIGDAAGQANPITFGGIRTGMVAAKMVAEAIVNGSLEGYARQ
                     WPRSPYASSSYVRAFDSLRGMDNAELSRSVRPFRKGYGTRSGIKALLNGKKYRELYHA
                     YDLGAKWGW"
     gene            complement(18271..18936)
                     /locus_tag="PKM11_05275"
     CDS             complement(18271..18936)
                     /locus_tag="PKM11_05275"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47950.1"
                     /translation="MMRSRGWNHRAKLYFSLTIILIIAAWTYTWFSREVPLHHHLLIP
                     FSFVTLGMAIKYGDQVFDLNIGSKRKAVLLSVPIGLLMGALIFLDEGSATIFIGLLLA
                     LLIASKYDNIAFKLGFIVAGSIAVLAVLNGNPFHLVGALAVMLAAFADEILSDRGDKM
                     NGGTMSLVLKERPVLKVAVLVLCLTGALPTLLYFIAFLGFDTGYSFVEQISLTGGIGR
                     REA"
     gene            complement(18993..>19976)
                     /locus_tag="PKM11_05280"
     CDS             complement(18993..>19976)
                     /locus_tag="PKM11_05280"
                     /inference="COORDINATES: protein motif:HMM:NF012398.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HNX47951.1"
                     /translation="LFQLAVGSGSQVGEAMATSDVDRIIFTGHADVGRRIMTLASQRL
                     TPITLELGGKDAMLVLKDADLKRAARAACWGAFVNSGQTCVAVKRIYLDKSVEGKFTS
                     LLLKEVAAIKQGFDLNDASISMGSMISEGAVKEMEAQMSRAREQGAEVLAGGMRVERP
                     GCFFQPTVVKAEQHLDIVRKETFGPIVALLTFQDEMEAVRLANDSPFALNGSVWTSDL
                     EKGRRIATQLRSGTITINNVAYTYGLGATPWGGRGDSGFGRTHGDAGFEELIERQHVH
                     IDRGKFSSEIWWPPYGEEGMEAMHDFTGLAFNGEKDGLLQKLLKARRLMRR"
     assembly_gap    19977..20076
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <20077..20756
                     /locus_tag="PKM11_05285"
     CDS             <20077..20756
                     /locus_tag="PKM11_05285"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47952.1"
                     /translation="ISGMRKSFVLLMALTVLMAAFIPAPAAAETDSGEALIPAGGHLV
                     LLNFTVTEDHWDDPANAGNVRWLVYLDDASMQDSFDVFVMTADTYQEYISNGTYQLVI
                     DWGSNNAGVVPAYNLVYLFDKGDYVLLIDNTDAGGLFYTPAELKVHYEYDAQNVDVPK
                     ETRWDLFIALMVLVALLGVAFLLLLNMWVKHRMLRVDEERKKRCSNCGKVSISDGEYC
                     QYCGKER"
     gene            complement(20757..22505)
                     /gene="infB"
                     /locus_tag="PKM11_05290"
     CDS             complement(20757..22505)
                     /gene="infB"
                     /locus_tag="PKM11_05290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HNX47953.1"
                     /translation="MTIRQPIVSVLGHVDHGKTSLLDYIRGTAVMTHEAGRITQHIGA
                     TEVPLDHVNKVCAKLLGSRKFTVPGLLFIDTPGHHSFTTLRARGGSLADIAILVIDIN
                     EGLKPQTLESISILKRFKTPFIIALNKIDLVDGWVTHPSAPFIISEKTQSEEAQAALS
                     EKLYQVVGRLAEEGMSSERYDRIEDFTKNIALVPISARNGEGVPDLLLVLVGLAQRFL
                     EEHLKTELGPAKGTVLEVKEERGLGQTIDVILYDGELRQGDSIALGTRGKPLLTKVKA
                     ILKPKPLDEIRDPRDKFDRMKEITAAAGVKLLCQNLEGVVAGGPLRAYKNNQDQVLKE
                     IAEETKITIEVADNGLMIKADALGSLEALAYECKRADIPIRKYETGDISKRDIIEVSA
                     YTDPLHKVVLGFNVSMLPDAKDALTTHESKVFLNAVVYGLIDDYQKWVGEQKRLAEVE
                     KRSLVAFPGKIRVLPNCVFRASKPAIVGVRVLAGRIRNNQKLVASDGREIGRIRSLRT
                     GEDVLKEAIVGQEIAVAIEGATVGRQLDVEDILYVDILESEIKNLQDYDLNLDEKETL
                     EQLLVIKRKSDPFWGM"
     gene            complement(22617..23066)
                     /gene="ndk"
                     /locus_tag="PKM11_05295"
     CDS             complement(22617..23066)
                     /gene="ndk"
                     /locus_tag="PKM11_05295"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0006165 - nucleoside diphosphate
                     phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HNX47954.1"
                     /translation="MERTFVMLKPDAVQRGLMGQIVSRLEAKGFRPVAMKFMRIPREL
                     AERHYGEHKGKGFFPGLISYMTSGPVLVMVWEGDNIISVMRGMMGKTNPVEAAPGTIR
                     GDFAQQTGRNIIHGSDSSESAKREIELFFNDYELQSYEACNKVWLFE"
     gene            complement(23075..23416)
                     /locus_tag="PKM11_05300"
     CDS             complement(23075..23416)
                     /locus_tag="PKM11_05300"
                     /inference="COORDINATES: protein motif:HMM:NF013415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24e"
                     /protein_id="HNX47955.1"
                     /translation="MVEQHLCVFCGEQIEPGTGKMYVRKDGTTLMFCTNKCYKNMIEL
                     KRVARNTTWTKAYATKKGISIAAKEKSDAKVEETEATAEAKVEKKSEPKTKTVSRKKA
                     RAAKKAEAAKE"
     gene            complement(23430..23642)
                     /locus_tag="PKM11_05305"
     CDS             complement(23430..23642)
                     /locus_tag="PKM11_05305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S28e"
                     /protein_id="HNX47956.1"
                     /translation="MADEDSIPSEVVEVIGRTGMTGEATQVKVRVLDGRDKGRIITRN
                     IMGPVRMGDILMLRETSREARKLSLR"
     gene            complement(23655..24026)
                     /gene="rpl7ae"
                     /locus_tag="PKM11_05310"
     CDS             complement(23655..24026)
                     /gene="rpl7ae"
                     /locus_tag="PKM11_05310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015491644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7Ae"
                     /protein_id="HNX47957.1"
                     /translation="MAKAVFVRFEMPKELKDKAYEVVELARDTGKLKKGTNEVTKIVE
                     RGEAVLVVLAEDVQPPEILAHMPMLCEERNIPYVYVDSKAQLGASCGLEKPTASIAIL
                     DAGKGKPILEALVDQVKKIKG"
     gene            24246..24470
                     /locus_tag="PKM11_05315"
     CDS             24246..24470
                     /locus_tag="PKM11_05315"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47958.1"
                     /translation="MKLPLSRKIFAGIGAVLAFVGNGLAYYMMTAMHEETVLFITTDV
                     FTYERDAIITPVAIGVIGVILLLIAALSED"
     gene            complement(24483..25211)
                     /locus_tag="PKM11_05320"
     CDS             complement(24483..25211)
                     /locus_tag="PKM11_05320"
                     /inference="COORDINATES: protein motif:HMM:NF024988.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HNX47959.1"
                     /translation="MIEGENELLRKIEELRQGLDSLGRSVTSLRKDGMENAFHEQIGA
                     SYLENNRDAVRAVIRASQAPSHPIVNEISDLYDVAMERYEMNDLDNALSALDRVRDLV
                     ASSAEEEIGADLRTVLLPVLDRSREQMAMLETLRFHTGRPGVRRSCDSAYAGIEPESL
                     EGLLSPLSNAIRLKILALLYTNSRNFSEMVSELQIQKGHLQFHIRKLVDAGYVKVDRR
                     THLYSIEVKGLMAVEGLGQLFAKF"
     gene            25282..25920
                     /locus_tag="PKM11_05325"
     CDS             25282..25920
                     /locus_tag="PKM11_05325"
                     /inference="COORDINATES: protein motif:HMM:NF019413.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1638 domain-containing protein"
                     /protein_id="HNX47960.1"
                     /translation="MKIGVVACESFRKEMDLLTEGDPDIVHKEYLEFGLHSYPQDLKI
                     AVIDHVNALRGKVDAVFLVFGTCNSLKDVCKELVVPTVTIEADDCVGALLTNEEYARE
                     KKVCAGTLFAIPFMSEMGTDYFEKEFESKMPDHEQLGVDSEWYLGILFDGYSRLLHVD
                     TGVGDARALQKSSKDMADRLKLRFEERQGTLQVLKDRLQDTKELASSLTRSG"
     gene            complement(25924..>26469)
                     /locus_tag="PKM11_05330"
     CDS             complement(25924..>26469)
                     /locus_tag="PKM11_05330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate synthase subunit beta"
                     /protein_id="HNX47961.1"
                     /translation="SGATPFGAWTTTTPVGSKVEGKREFKKDLMAIIAAHDPPYAASL
                     SIAHFNDFIRKVEKAKSKKGFRFLHVMTPCVPGWRSDPSMTVEISRLAVETGMWTLYE
                     LEDGEARTTYRPQTMLPVTDYLKVQGRFRHMDNDDVAKLQEWLCRKWYLHYGGVEQPV
                     CANFEKVRPVRQPHEEQLHFI"
BASE COUNT         5244 a         7795 c         7601 g         5529 t
ORIGIN      
        1 aaggacgcct acgccgcagc gcattccgct gagataatca accgcacggg aatgggagac
       61 gtctcgggaa taatgcgcgg cggcatcgag ctgcgcaaga agccgggatt gccgccgatc
      121 ggtcacgtgg accgcatgaa cgggaacatg gacctcgtgc ttgccgtcgt cggtccgtcg
      181 attccgacgg ccgagatgct ttcggaccgg gagagactgg agaagatcaa ctccgtcggc
      241 tcccgatgcg tcgattcgct gttgaaggaa cctacgctag agaacttctt ccgtctgtcg
      301 aacgagttca tggacggttc cggactggcg accccggaga tcagaagggc ggtctgggag
      361 gcaaagaaat ggggctgggc cagtcaggcc atgatcggca actccatttt cgccaccggt
      421 ccggacctgg agctgttgca agaggcgctt acgcagttcg gtgacgtcta ccgatgctcg
      481 gtggacaaga aggggccgag actgctctga tcactcgtat aacgtgaaaa gctgatcgtc
      541 ctggcccacg tcgaaaagtc cgatacgggc gccgcagtcc agccagccgt gcgcgtagtt
      601 gacggaagcg aacgcgttga cgtaatcgcc ctgctcggcg aagtgcttgg cgtccgagaa
      661 gtacgtccgg gccatctcca ggaacgaatc tgcgagcttt ctattgaagg agcgttccgg
      721 agcggatatg gtcaccttct ccaaagcgcg cttcgtgatc gataggtatc gctccaaatg
      781 ctcctgggag atggtgtccc tcatctcaca gcctcttgga ggggatgatc tccaccgact
      841 cgccgccgtg cctgctttgg cgtggacgga cctcaacgaa cagcggcatc tggatgttgc
      901 cgcccatgat cagcgccacc ccgatcggca gccgctgtat ctcctggtcc atgccctcct
      961 gcagaccttc cacggatgat acgatcgctt tcaggtcatt ggggttggtg accttgagta
     1021 tcatctgggt gttgcactgc gatagtacgt tcttatcgat cttggccgcc ctctgcgata
     1081 ttatagtcag accgagaccg aacttacggc cttccgcggc gatggtccgg aatatcttgg
     1141 agcaggaggt cacgccctgc tgcgggcaga agttgtgggc ctcctcggcg atcatcatca
     1201 tcggcgggac cttgccgagc ttgcgcagct cgaacatggc ggtcgccagt ctcgttacga
     1261 taagctcctg gatgtccgga ggcgtgccct tgagattgat tattgtggtc ttcccagggg
     1321 atatgagctc gtctatcttg gtgccctgcg gggcgaagat gttcacctcg ttcaggtagg
     1381 ccagctcggc gatcagcgtc tggttgttgg cgtcctcgtc ggactccagc atggcgatta
     1441 tctccttgag accgtaatcc ttcttgaccg ccttgaggcc atcgatcgcc tttcgcagag
     1501 cgttcaggta caccttgccg ttcttgatgg tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nccgatgacg tccttgatga gctggtcctt ggcccggtag accatgtccc
     1681 cggccttgaa tggggaacgg ggaacttgta aaagcttcct ctcgtcccgg taacctagaa
     1741 ttgtgatctg ggcgatgacg atctcgtcga tctccacgtc catgccctcg ctgagacgtt
     1801 tcgcccgttc gagcgtgagg tcggtcttgc gctccatgtc cgcgacctga ccgagcaccc
     1861 agccatgtga ttgatgaatg acctgaatgt aatccatctt ctgcaggtcg cccaggaccc
     1921 tcaggtggaa ggacgtcgcg ccgacgttcc cgtagatcat gcccacgccg tccaggtgtc
     1981 cgtacttctc gtcctccaag gtgtgcttgg agggctcgcg ctccctatga acgactacct
     2041 cgtccggagt gccgacgtcc tcgacgttgt catccaggat ctcttcctcc acgggcacct
     2101 cgtcctcttc ctcggaagga aggacggctt taccgctgga ctctgaaata gaattggttt
     2161 gcattcccat ccgtctatga tataaggcgt gcacgataaa taagttgggg atatgctgaa
     2221 cgattcgaat aacatgattc ccataggcat catgcgcgac cagccgggca gaatcactta
     2281 tttatcggaa acctaatctc caggcgatga tagttatcgg cggctccgcc tcctcgaatc
     2341 tggccaagga cctggccaag cagttgaacg cggaatacgt gcaggccgtc aacaaggtct
     2401 ttccagatgg cgagatctac acccgcatcg agcgcgagtc gctgagcggc gaagtggtca
     2461 tcgttcagaa ctcctatccc aacgagaagc tggtggagct gcttctgctg caggacgccg
     2521 cccggggact gggagctgag aaggtaactt gcgtcattcc ctatttcgga tacgcccgac
     2581 aggacgagcg cttcaaccgc ggcgagccgt tatcggcccg ggtgatggtg gagcacatcc
     2641 agatgaaggc ggacaaggtc attctggtgg atatccacaa cccggagatc atggactggt
     2701 tcaccaaggc caaggtgaag gacgttcacg ccgccccctg cgtcggggac ttcttcaagg
     2761 agttcggggt ggacctcgtt ctcgctccgg acgagggcgc gttgaagcgc gccggatggg
     2821 tggccgaaaa gctgggcgtg gactgggact atctggttaa aacgagactc tctggcacgc
     2881 acgtgcacat gacgcccaag aacatcgacg ccaaggaccg caaggtgctc atcgtggacg
     2941 atataatctc cacgggcggg accatcgtcg cggccacgga agaactgaag cgcctggggg
     3001 ccaggaccgt gatggccgcc tgcacgcacg gcctgttcgt cggcaacgcc ctggacaacc
     3061 tcaagaagca cgtggacaag ctggcctgcg ccaacaccct ggaatcggag gtctcgcaga
     3121 tctccgtggc gccggaagtg gccaaggcca tcctggaatg agggcggcaa agtcttaaag
     3181 cgatactgtt catttcgaat cattccgtac tcagggtgca gcacatgagg aagcaagagg
     3241 atttcagcga gtggtacaac gagatcgtgg aactggccaa cctcaccgac aagcgctacc
     3301 ctatcaaggg catgaacgtc tggacgcctt acggctggaa gatcatgcgc ttcatcgaca
     3361 cctacatccg ggaggagtgc gacgccaccg accatgacga ggtctgcttc ccattgctca
     3421 ttccggagac ggagttcaag aaggagaagg accacatcaa gggcttcgac gccgaggtgt
     3481 actgggtcac ccacgccggt ctcaacgaac tggacgttcg tctactattg cgaccgacca
     3541 gcgagacggc catgtacccc atcttcgccc tgtgggtgcg ctcgcatacc gacctgcccc
     3601 tgaagaccta ccagctcgtc aacaccttcc gttacgagac gaagcagacc agggccttca
     3661 tccgtgtgcg ggaaattcac ttcttcgaat cgcacacctg tcacgtggac gaggcggacg
     3721 cgcagctcca ggtggaggag gatttcgtaa ttttagagaa catcatgaag cacctctgcc
     3781 tgccctactt cctgctccgc cggacggaat gggacaagtt ccctggagcg ttctacaccg
     3841 tgggagtgga cactctgctc ccggacgggc gcagcctgca attgggttcc atccatcact
     3901 accgggagaa cttctcccgt ccgttcaaca taacgtacga ggacgaaaag ggagagcaca
     3961 agttcgctca ccagaccact tttggtatgt ctgaaaggct cgtcggcgcc gtggtcgccg
     4021 tgcacgggga cgacaaggga ctggtgcttc cgccggacat ctcccccttc caggtggtcc
     4081 tcattccgat cttggccaag ggaaacgtgg agaaggtggc cgaggagtgc cagaagttga
     4141 agcaggagct caccgccgcc ggcatccggg tcaagctgga tgacagcgac gaacgcccag
     4201 gcagcaagtt ccacaactgg gagatccgcg gcgtcccgct ccgtttggag atgggaatgc
     4261 gggacatcga gggaggaaag gtcgcttacg cccgtaggga cagcggcacg aagggttcgc
     4321 tggaccgcgc gaccgtcgtc tcacaggtca gggataccct caaccagata tccgacgaca
     4381 tgcgcgctaa agcgcttgcg gcatcgaacg gcgccataca ggacctggac tctctggaca
     4441 aggtgccgga gaaggtggtc cgcttcggat ggtgcggcga ggaggaatgc ggccgcaagt
     4501 tcgaggaaag gaccggcctc aagatgctcg gctcgccgta caacaaagag gactatcacg
     4561 gcaagtgcat cgtctgcgcc aaggccgtcg agaaccccac ctacgccgcc cgctccatgt
     4621 gatcaaagga tgacggcgaa cggtatggcc accagcagga ttatggtgac tatcagcccg
     4681 atgtccatgt tccagccctc gcgtccggcc accaccgtct gcgtgtagtt gagcagggga
     4741 gccaacaaag ccaggaccat cccggccatc agcagccatt ggtatccgta gttcatccca
     4801 tccagggtca tggaggtggt tatgtacagg gcgaagagcc cgagggcgcc gatggtcacg
     4861 ctgaccgcca tcacgaccca gtccagaatc tccagggtcc tctccgactg tccttcgcgg
     4921 cgccggttga agaccactac ctccaacagc cccaatacgg ccagcactac tccgatcatg
     4981 atcatgaagg tgggttcggc cttcagctct ccgtggacgt tcaggtcgcc gcgcataccg
     5041 aagatgacca caccttcggt catgaccagg caggcggaga acattcccag ccactccagc
     5101 caggccaggc gacggttggc cagcggctcg tagtacaggt aaacgaaggc cagcaccccc
     5161 agtaggaaca gctggccggc ggccagggcc acccatctct tcccgatgcc gccgaagtcc
     5221 tcgatcgtcg ccggagaggc catgaccagg aacaccaggg atatggccag gaccgcgatc
     5281 gcggccatga cctgcaggcg cttcatcagc ctttcgctga tcctccgcag ctgcgggaag
     5341 agcgggatga acagcagaag accgagcacc agtaggaccg cccccagggc catggtcatc
     5401 atctggtcca tgaccagggc gtccaccagc tcgatctccc gggctagtac caccagggcc
     5461 accccttcga acattatcag aagacccatt agatgcggca agaaccaact gcccaacttc
     5521 ttcaaatatc ccgcctctgg acaatattca gttggacttg atataatgct tccgttgccg
     5581 cctactgctt gtatttagcg agcagcagac cgaaaacgcc caacccgagc aggatgatga
     5641 agatggaata tacgcccata ttatcggcag cgaagatgtt ccagcttcca taagtgacgc
     5701 cccacgccca gtagaacagc accgctgcca ccacgaggag cagggagaat attgttacag
     5761 ccttcttggg gtaggcttgc tcggccatcg ggcgtcaaac gtggtgggcc tattaaaatc
     5821 ttcttccgaa gagctgtgag gaacaactgt cgatccgttg gccagaatta tccgatgatc
     5881 aaatgctgac gatcgatgag ttaatttaat cgatttataa aaattataat ttttatcttg
     5941 gtctcgatgg aagaggtagc gtatgacggg aacgccttct caattttgcc cctaacggaa
     6001 attgctaccc gttttgcttt gtatgcaccg aacaatatca aagtgtcggg aacatcggca
     6061 tcaagcctga tgcatacccg tctgaccaga acctcttctt tatcttccgg gccgatgaac
     6121 actatgtatt tttcgatgtt gttgagcaga ttctccactc gtatggtaag atcgaccggt
     6181 tcgcctatgt taggtgattc gaggccgatg aagttactga tgatgttgtt ctgcacagcc
     6241 tctgcgatgt gcagaccgtc tcgaccatac ctatgatgga tcttgtttct caatgactgt
     6301 gtcctttcct gatcgttctc caattcccta agggctagac ccatttgcgc caagagcctt
     6361 aatttcttat ccttaaggac atcgctgaga attttccatt caggactctt cctctgtttc
     6421 ttcacccgat cgatggtgtc ggaatcttca acaaaaacga tctcgtggtt tcgaaaacgc
     6481 tcaacccatg ccagagcttt ctcctcggca tgttcgagca gacctttggt gatgcccgct
     6541 agaacatcgg tgttcgacgg gatttcgtcg gacatgcagc tttcctaaaa gatctctccg
     6601 tggtcctcga aatatcctgc aaagctgagg ggattgctgt cgaggatgat ctcgctgccc
     6661 tgaaggatga ccatattgtc gatcctgacg gcctcatcta tgtaaggatc gatgatcata
     6721 tctccactgg aatcatatat gaacgtccca tctgaggaat atcccatttt ttctaaaatg
     6781 gcaatcttca gctcgatcgg ctcgttcttc agggataaca tttccattca tttcaccttg
     6841 gccggttcat gaaagaattc tggtcgagac tattaatcgc tttggtgtac aattaattgt
     6901 gggtcgtctt agtggtggaa tcgccgatga tcaatatcgg aactttcctg tgatcctatc
     6961 atgcccctat cctcatcgta caggcaatta ggacggtgag gagcggcgtc cgtcgtacaa
     7021 tatcattcat tcttcaacgg actatcttca atggtccact ttttctccgt ctttagtccc
     7081 gttcaaatca ctttgatata tcggtaaatc gatgttcgcc atcaggaagg gatggaactg
     7141 gacctttgga taccaataat catatggctg gcgatcggcg cggggatcgc tttctacctt
     7201 taccggctca tggacaagga aggcaaggtg gaggtcatct gggtcgtcat cggcttcctt
     7261 ctctccgtgc tcggcctcat ggccttcatc ggcgcacgct ccatgaagga gaaggaccgc
     7321 gacaaggccg ttgatccgaa gagctaccag cctccggagt acaagctcaa ggaggaggcg
     7381 ccaaaggaga aggccccgga agagaagaca ccggtgccgg caccggagcc gaccccggaa
     7441 ccgaagaaga aggaggtcaa gcagatcgag ggcattcccc gttgcccgga gtgcggctcg
     7501 gccatatcct cttccgacgt ccgttgccgg gactgcggcg ccaagctcaa ggactgagga
     7561 aacacttttt atccccgggc aggatgccta ggcatgcttc ccgagggctc cttgatctat
     7621 cttttggacg aaaagggcaa gaggacctgg ctggtcctca acaagggaat gcttaagttg
     7681 ggcgccatgg gcgtggtcga cggcgacaag ctgctggcgg cggaggacgg ttccgagctt
     7741 acgttggccg gcaaacgttt ctggatactg gttccgggcg cctcggagat gatgacctcg
     7801 gtcgagcgag gagcccaggt cataaccccc aaggacgccg cgaccatcct tttggagctg
     7861 aacgtgaagt ccggcgatac ggtcctggag gcgggggtcg gctccgccgc cctgaccata
     7921 gcgctcttga accaggtacg tccgtggggc aaggtcgtat ccatggagat ccgcccggag
     7981 ttcgctgaga agggcaaacg gaacgtggac aaggccggcc tcgctgacgc ctggcgtttg
     8041 gagataggcg acgtgagaaa ggaccgcctg gacatactgg ctgacgcggc cgtcctggac
     8101 atgccggacc cctgggacgc cctggacaac gtctcctcga tgctcaggaa tggcgggcgc
     8161 ttctgttctt acgtgccgaa caccaatcag ctggaggaga tcgtccgcaa gctgcggaac
     8221 aagggattcg tggagatccg cagctacgag aacatgcagc gggagatggt ggtgcacgag
     8281 atgggggtgc gtccctcgta cgaaactctg ggccacacgg gatacctggt gttcgcccgc
     8341 aaggtgtccg tttgagccgt tctcttaacc cttaaatatc ccataacatc tcgcagtccc
     8401 atggacctgg ccttcgcgat aaccgccttc gcctccatat tcgccatcat gaacccggtg
     8461 ggcaacatcc cggttttcgt ggccatcacc gaaggctaca cgccggagct gaagcgcaag
     8521 gtcatcaaca aggtctgcat cgtggccggg ggcatcctga tcatcttcgc cctcttcggc
     8581 aactacatct tcgacatcta tggcataacc atcccggcct tcaagatcgc cggaggcgct
     8641 ctgctgttct ccatcgcctt caccatgacc aagggtcagc tgaccaaggc caagatgacc
     8701 gatgaggagg aaaaggaggc cacggagaag gaggaggtcg gcgtcgttcc gctaggcatc
     8761 ccgctcttcg ccggaccggg cgccataacc acggtcatga tctatgtgtc ctacgccctg
     8821 gactcgccgg accccacggt gaacttcggc ttcatattcc tgggcatctt ggtcacggtg
     8881 gtgatatcgt tcttcctgct gaggtacgcc gatccgttgt tcaaccgcat gggcaagagc
     8941 gggaccatgg ccttcaccag gatcatgggt cttctgctgg ccgccatggc cgtggagttc
     9001 atactctctg gcacgttcga ggcggtgtcc cactattggg gcatctgagt gaaaggcaga
     9061 agattaatta ctggaggacg attcctcagc cggtgcatct atggttgtgg cagagataag
     9121 gatagagctc aagccgggag tggctgaccc ggagggcaag aacaccaaga aggccctgga
     9181 actgcttggt ttcaaagata tcaagggagt gcgctccatc aagatgttcg agatcgagat
     9241 ggacgccgac ccggccgtcg cccgcaagga gtgcgaggag atgtgccgca agctgctggc
     9301 taacccggtc atccagaagt tcagggtaga cctcaggtga aggtcatgcc tctggaccac
     9361 ttattcttca agcgcgacgt gccattccac ctggtggaga tagacctggc caaggccaag
     9421 gacgatgagc tcaaggtcct gagcaaggac atgggactgt ccctctcctt ggatgagatg
     9481 aagcgcatcc gcgatcactt cgtttccttg aaacgccggc ccacggacgt ggagctggag
     9541 tcgatagccc aggcctggag cgagcactgc tgttacaaat catccaaggt catcctgcgc
     9601 gagcatatct tcggcattga caacggcaaa gttctgtcga gaggcgacgc cggggtcatg
     9661 gagttcgacg acgagtacgg ttacgcgctg cggatagaga gccacaacca tccatcggcc
     9721 atagagccgt acggcggcgc ggccaccgga ataggcggaa tagtccgcga cgtgctgtgc
     9781 atgggagcgc agccgatagc cctcatcgat ccgctgttct tcggccctat cgactataag
     9841 ggagagcttc cggccgggtc caagacgccc aagtacctgg tgtctggcgt cgtggccgga
     9901 atacgggact atggcaaccg catcgggata ccgaccgtct gcggcggcct ttacttcgat
     9961 gaatcatacc tgggcaactg cctggtgaac gtgggttgcg tcggaatcgt taaaaagaaa
    10021 gatttacgca acaacgccgt gggcggcgtc ggcgactacc tgatcctttg cggcggtcgt
    10081 accggccgtg atggaattca cggagtgacg ttcgcctctg ccgagctgag ctcgaagtcc
    10141 gaggacgaga gccgcggtgc cgtgcagctc ggagatccga taaccaagga accgctcatt
    10201 cacgcctgtt tggaagtcaa ctcgctcggc ctcatcaatg gaatgaaaga tttgggcggt
    10261 ggcgggcttt catgcgtcgt tggcgagatg gccctgtccg gcggatgcgg cgcggaggtc
    10321 gatcttgaca aggtaccact gaaggagagc gggctggctc cctgggaagt gtgggtctcc
    10381 gaatcacaag aacgtatgat gctggcggcg tccgaggaga atgtggaacg catactggac
    10441 ctcttcgccc tgtgggacgt ggacgccacc gtcatcggta aggtcgtccc gggaaggcag
    10501 gtcaccctga aatggatgga cgtgcaggtg ttccaggtgg acctggagtt cttaacgaag
    10561 gggccggagt actgccgtcc ctgcaagatc gagaccccct ccaagaccat caaggaagtg
    10621 cgtccgttac tgccggacac caagacagtg ctcctggaac tgctggccga cccgaacatc
    10681 gccagcaagg aatgggtgtt ccgcatgtac gatcacgagg tgcgcggcgg gacggtcgtg
    10741 aagccctcgt ccggcgtgat gaacaagggc ggcccatcgg acgccacggt catcaagcct
    10801 ttgccggata gggagagggg attggcgctg gcgataggcg tgaacccctg gttctgcgga
    10861 ctggatgctt accggggcgg catggcctct atagacgaag cgtgccgcaa catcatcgcc
    10921 gtgggcggtt atccggactc gttcaccgat tgcctcaact tcgggaaccc ggagaagccg
    10981 gagcgcctgg gagagctgaa gcaggcggtg gccggaatgg gcgacctggc tagattcctg
    11041 aacttgccag tcccttccgg gaacgtttcc ctgtacaacg agaccgccag aggctctgtg
    11101 cttcccacgc ccaccgtgct cggactggga atagtcgagg acgtgcgcaa gtgcgtcacc
    11161 accgacctga agaaggaagg caacctgctc tacctggttg gggagaccaa ggaggagttc
    11221 ggcggttcgg ccgtttaccg caggtacggc ggaaagggag gagaggtccc ggaggtcatc
    11281 cctgagcggc tcaagcaatc catggacgag atgcacgccg tcatgaagaa ggatctgatc
    11341 aggtcctgcc acgatgtctc cgacgggggc attgccgtgg cggtagccga gatgtgcctg
    11401 ggaggcaaca ttggcgccga tgtgagcacc ggctacgacc gctggtacct gttctccgag
    11461 agcagcaccc gctggatcgt ggagatagaa ccgtccaaca agaaggagtt cctttccagt
    11521 atgacggtcc cggtcctgga attgggcaag gtaggcggca agtccctgcg catcaaggac
    11581 cgctgcatgc tggtgaacct gagcctgagc gagatgagaa aggcctggag cggcgcgctc
    11641 ccgaagctga tggggtgaac tgatgaagga cgtcaaggtc tgtgtgctaa ggatagaggg
    11701 tacgaactgc gaggacgaag cggctcaagc cttcgcctcg gtcggcgcat ccccggagaa
    11761 ggtccacctg aagcagctat tgggacaatg cccatccgat ctgaggaggg acctcggaag
    11821 ctacgacatc ctgatgcttc ccggcggttt ctcggccgga gattacgttc gtgccggagc
    11881 catattcgcc gctcgcatga agagcgggct gaagaacgag atagttcgtt tcgtggagga
    11941 cggcaagccc gtgctcggag tgtgcaacgg attccagata ctggtggagc tgggattgct
    12001 cccggccatg gacgagacca tgtccgaggc gccggaggcg gcgctctata cgaacgattc
    12061 aggccgtttc gaatgccggc cgaccctgct ccggatggag aagaggcaaa ggagcgtctt
    12121 cacctccaac attccgaacg gttcggtgct catgtacccg tccgctcacg ccgaaggcaa
    12181 gctgatgttc ccccactccc gacagagcaa gatgctgaag cggctgctgg acaatgacca
    12241 ggtcatgttc cgctatgtag atccggaagg ggagtacgcc ggatacccct ggtgcccgaa
    12301 cggttcgctc tacaacatcg ccgggatctg caatcccgcc gggaacgtgc tgggcatgat
    12361 gccccacccg gaacgggtgc tgaaaaggga gacccatccc gactggaccc gagcgaagcg
    12421 aaaggaggac ggcgatgggc tgtccatatt ccgttccgcc gtgaagagcg tcaagtgatc
    12481 ataggttgag gtggatgcgg acctcgatct ggtccccatc ctccaggccg agcgtgcggc
    12541 gcaggtggaa cttgcatacc acttccagga cgtcctcgta gtgcgagcgt ctcggaagaa
    12601 cgacagcgca ctcgatgttc tggatgctgg ccgggatgca gtgcacgtcg ccgaaggtcc
    12661 gtccgttgcg ctcgaacccc ttgatgtcta tcgtccgacc gttgcgcagg gtgtccagct
    12721 tgtgatgctc cgtcgtgagc agcttgacgt tgagcgttcc ctcgtacggt ttgaagccta
    12781 gcttttcgac gaactgctcc atgtagcccg gttgcgtgac gtagtactgg ccctcgccca
    12841 tgccctccac tacggtacct ttgatcacca gttcgtcctt catctcgaag atcttctggt
    12901 actccaggta ctccttgcgc agcatgtccg accccttgga ggtgatgcgg atgcgttggc
    12961 gcctggcgcc gagatcgcgc tcgatgagct tcccgtccag gagctccagg atgcgcttgg
    13021 acgccgattg ctgcgacatg tccagcatgt ctccgagctc gcgtgacgat agggcgacgt
    13081 aatcgtgcaa tccccccatc agcgcgatgc gcctgagggc ggtaacgaac ttctcgtcgt
    13141 tctctggctg caaaggtaac atctccgacc tgctactacg taatccgtaa ccgattactt
    13201 tcctggttat cgcttatttc catttaatag attactaggc gggcggatga taaatatcgc
    13261 cttcgttcat tcccctctta tgacgaagga ccggcatgtc atggaagtcc tgggactgtc
    13321 cagggtggtg gtggagaacg gcgtggtcgt ggacgtcagc gagccgcgcg tggagttctg
    13381 tcccctgttc tacaagcaac ggggcataga gaagctcacc aaggagagca tacgcgggaa
    13441 cgtggagttc cgcataaggg acttcggcat attcaccgaa cgccgggaga tgcgcatgaa
    13501 ggacttcctg agcttcggca tctcggaaat aatgagcatg tgcgtcatca aaggcatact
    13561 ggactgctcg gtatgcgtgt gcgacggctc cggaacggcc gtcgtcgaag atccggagat
    13621 catccagggc ataggcggta ggatatccgg catggtggag accaccccgc ttcagaacgt
    13681 tataaacgcc atcggaaggg accgggtnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13801 nnnnnnnggt cagaagctcg gcgccatgca agtggggacc aaggtcccgg tgttcgccat
    13861 aaccgataag ggaaaggaga tctgcgagat gcgtttgaag cagatcaaca aggaagccaa
    13921 gagcggaccg gacgatcccg cccggccgtt gatatgatca ttcctcgatg accaaacgct
    13981 ttcgggagcg caggaatatg gcgcgtatgc cctcctgcct catctttcgt ctcagaatgt
    14041 aatcgttggt gaccaccatg gcgcctaacg ccttggccac ttccatgacc ccggcgtcac
    14101 cctgcgtgga cgtctcgtaa cggatgtact tgccggccag catcaaagcc gccttggagt
    14161 gcttgctgtc ggaacgcttc agttcgccga tgaccggccc cggtacgtac gcctcgaact
    14221 ccccgaaaag gttcgccagc tcgaggtcca agttcatctt gaactcgaat ggcatgagga
    14281 gcgcgttggt atccaggacc accttttgca tgaagcctca ctctacgatg ccgtagccga
    14341 tgaggcgcca cttgttggcg atcttgcggg agacggccac gcgctgacca atctcggcgc
    14401 agaccgggat cttcagggcg acctccgact ggtcgccgcg ggcgctggtg accaggccga
    14461 ccgtcgtcgc cgtcccgatg ctcagcatca ggggctcgtt ggtcttgatg ttctccacca
    14521 ccatgtcgtc agtggtaccg acgaccctct ccaggagatg ggtcttcatc ttgaacttga
    14581 agtggacctc aggtaaggtc ccgggcttgc ctacgacacg cccagtgaga ccgtccgact
    14641 tggtgaaaga gggatcgagc ttggtgccga tggccacgag accgccgggc cggatcttgt
    14701 tgaccgggcc tccgccggtg tgcaacgatt cgatggtggt ggtgatggtc tcccaggtga
    14761 acttgccacc gggctgctcc accttgcgtc cgggggagat ctcgacctcg tccccgacct
    14821 tcaggacgcc ctgcatcagc gtaccgccga gcacaccgcc cttgagctcg tttatgtcca
    14881 ttccaggctg gttgatgtcg aaggagcggg cgacgaacag cttggccgcc ttcttctcat
    14941 cgtgcttcct ggtcgggatg tacttctgga tggcgtcgat cagcttgtcg atgttgacgt
    15001 catgatgagc agaaactggt atgatcggcg cgttctcggc gatggtcccc ttgacgaact
    15061 tcttgatctg gttgtagttg gccagggcct cgtcgcgagt gacgatgtcg atcttgttct
    15121 gaacgattat gatgttctcc accccgatga tggagagcgc catgagatgt tccttggtct
    15181 gcggctgagg acattcctcg ttggccgcca cgagcagcaa cgcgccttcc atcatggccg
    15241 ccccggagag catggtggcc atcagcgttt cgtgcccggg agcgtccacg aaggatacgg
    15301 accgaacgaa ttcggcctcg ccgccgcata ccttgcaagt ggtggagttg gaataggtct
    15361 cctcgcactt cttgcacttg tagaaagata cgtccgcgta acccagcctg atggagatac
    15421 ccctcttgat ctcctcggag tggcggtcgg tccagtcacc ggaaagggcc ttggtcagcg
    15481 tggtcttgcc gtggtccacg tggcctatca tcccgatgtt gacctcaggc tggcgggaca
    15541 ccttcattat ttcttctcct ctttcttcgg gaccagttcc tcgaccggct tggggccctg
    15601 agaaacgatc ttcatgttta tctggacggt gtcggtggcg acggagtggc cgcgcacgga
    15661 cttcctcctt cgcaggccgc cctcggtggt gtagaagccg gtgctgcatg tcagcaggag
    15721 cttcttccgg cgcggtccgg gtaggtcctt cctcatggcg aaaccgtcct tgtcgcttcc
    15781 gccagtgatc gtaagcttat agccaggcaa tcctacgaat atgccatcta tggtgtcgcc
    15841 tatcttcttc cctatcaggg agttggcgtg atgtccagac accgggacat tgtaggactt
    15901 gccggatttc atgtcgttaa caacggcctt gaattcaacc attacaaaca ccttttgagc
    15961 gttatgagta ttgcgcccta atgtagtacc gcttaaataa ttattggtgg cggcgggggt
    16021 gtgtggcgtg ccctcagcaa cgcttgacct ttatgtccct tccactgccc ttgacgagcc
    16081 ctttgaacgc cctcaacggg tcatcctcca gggcgttcag ggaatgcatc atatcgtccg
    16141 gagagaccag ttcgttcatc accgctccgg acagcaacga ccgcatccgt ccgtccagcc
    16201 cgtccgatga ccacagctcc accaacgtat cacgaagcac cgcgcccatc atcagctggt
    16261 cggccatgct ctccaccagc tcctcctcgt acctctgccc cttgccctgg gagagcatgg
    16321 cggcgtgctt tccggccagg ctcccgcaga tgtaggacgg cattatcccc tctcccacga
    16381 acgccagggt ctgaccggcg gcgtcgccgc agaacagcac gtttccgcgt accggccctc
    16441 ctaagaatcc agggaccggg gcgtccccta tcttgacctc caggaccttg tcgacatcga
    16501 agtagcggga gaccaccgga tgcccggtga tccaatcctc caagaaggaa cggcgggagg
    16561 cgttcacccc gaccaggccg aggccgacat tggccttcct cttccccttg ggtattatcc
    16621 acccatagcc aaggccgatc tcctgctcga tgaatatctg catgcactgc gggatgtcct
    16681 tcttggccac cagctcgaac tcgacgccgc gagcgacgtc ctgcggcgag aagaactccg
    16741 ccttgagctc cttggagagg gtggaatgca ccccgtctgc ggcgactatc gccttaggag
    16801 atagttcgac ctcctccccc tggtggctga gcaggcagct ctttaccgtg tcaccggcca
    16861 tctttaccga caggagcttg gtgtccgcct gcacatcggc cccggcgcgg gccgcgcgga
    16921 acgccagatg cttgtcgaat attttacgct caacggtcac cgcgtgccaa tatgcctccg
    16981 cgttatcgat gaccacttcc ctgccgagca cgaagcgggt gaactggtgc cgggcgacga
    17041 tggcgttctc cgggatcctc attcccgagc gtttgaccag ctcgagcccg atgacctcgc
    17101 cgcattgcac cggcgtcccg atctccttct tcttgtcgac catcagggtt ctcacgcccg
    17161 caagcgccga ggcgcgggcc gccccgctgc cggccgggcc ggcaccaacc accagaacgt
    17221 catattcctt catttcacca gccccatttc gcgccaaggt cataggcatg atagagttcc
    17281 cgatattttt taccgttcag cagggccttg atcccggacc tcgtgccata acctttccgg
    17341 aacggcctca ccgaacgaga tagctccgca ttgtccattc ccctcaggga atcgaaggcc
    17401 ctgacgtacg aggacgaggc gtaaggcgag cgcggccatt gccgcgcgta tccctcaagg
    17461 ctcccattca ctatggcctc cgcgaccatc ttggccgcca ccatgcccgt gcggatcccg
    17521 ccgaaggtga tgggattggc ctgaccggcg gcgtccccga tcaaacaagc gttgccttcc
    17581 accaccttat cgtaaccgta aggtatcggc cgtccctgcc tttccaggaa ctccgggagt
    17641 tcgtccgcac cgcgggtgaa gccgacccgc ttcccggaaa catgcgggaa ctcccagcgg
    17701 taaccgccct ggtacctctg atcgtagaag aagtgcatgg cgtcccggtc catcgttccg
    17761 ctggtgatga actgctcggc ccacagcagc cgcgggccgc cctggaagat ggtacgccgc
    17821 actagcgagt tccagccatc cgcccctacc agatattttg ccgagaactc ccgtccgtcc
    17881 ctggtcctta ctaggagatc gtcccctcgt ttcgtgacgt ccacggcggc tgcgcactcg
    17941 gagtggcctc cttctttctt cgctctctgc aacatgtgac gaaggagctc cggacggtcc
    18001 actatcacac cgtccgcctc cgtctcgatg accacctcac cgggccaatg ctccaccgcc
    18061 cggcgtatct ggaactgcac ggcgtgcggc tccaggggcg ccagttcctt gaaggccttt
    18121 gtgctcagcg cctctccgca catgcgatga tacctatcgt agttcctatc caatttctcc
    18181 agggaaagaa cgctgagctt accatcgctc aggtacgaca ggaagaaggc cgcggcggcc
    18241 ccggccggtc cggagccgat gatcatcaca tcatgcctct cgacggccga tcccccctgt
    18301 cagactgatc tgctccacga aagaataccc agtatcgaaa cccaggaacg ctatgaagta
    18361 caacagggtc ggcagcgccc ccgttaggca aagaaccagg acggcgacct tgagcaccgg
    18421 cctttccttc agcaccaagg acatcgtccc accgttcatc ttgtcccccc gatcgctgag
    18481 tatctcgtca gcgaaggcgg ccagcatgac cgctagcgcc ccgaccagat ggaaggggtt
    18541 gccgttcagc accgccagca cggctatgga gccggcgacg atgaaaccga gcttgaaggc
    18601 gatgttgtcg tacttggacg ctatcagcag agcgagaagc aacccgatga atatggtcgc
    18661 cgagccttcg tccaagaata tcagggctcc catgagcagt ccgatgggca ccgagagcag
    18721 aacggccttg cgcttgctgc ctatgttgag gtcgaacacc tggtcgccat acttgatggc
    18781 catgcccaag gtgacgaagg agaacggaat gagaagatga tggtgcagcg gcacctcgcg
    18841 ggagaaccag gtataggtcc aagcggcgat gatcaggatg atggtcaggg agaagtacag
    18901 cttggccctg tggttccatc ccctgctcct catcatgcgc caccgtgcac tttccaaaat
    18961 gccgcctggc tataaataaa cgcccgttct cctcagcgcc gcatcaggcg cctcgccttg
    19021 agcagcttct gcagcaggcc gtccttctcc ccgttgaagg ccagaccggt gaagtcgtgc
    19081 atggcctcca taccctcctc gccgtaggga ggccaccata tctccgagga gaactttccg
    19141 cgatcgatat gcacatgctg ccgctcgatg agctcctcga agccggcgtc gccgtgggtg
    19201 cgcccgaaac cgctgtcgcc ccgaccgccc cagggggtcg ctcccaatcc ataggtgtag
    19261 gccacgttgt ttatggttat ggtccccgag cggagctggg tggcgatcct ccttcccttc
    19321 tccaggtccg aggtccacac gctgccgttg agggcgaacg ggctgtcgtt cgccaacctc
    19381 accgcctcca tctcgtcttg gaacgtcaat agggccacga tcggaccgaa ggtctccttg
    19441 cgtacgatgt ccaagtgctg ctctgccttc accacggtgg gctggaagaa gcagcccggg
    19501 cgctccaccc gcatcccacc ggccagcact tccgcccctt gctccctggc ccgggacatc
    19561 tgggcttcca tctccttgac cgccccctcg gatatcatgg accccatgga tatgctggca
    19621 tcgttcaggt cgaacccttg cttgatggcg gccacctcct tcagcagcag cgaggtgaac
    19681 ttgccctcca cgctcttatc gaggtagatg cgcttgacgg ccacgcaggt ctgcccgctg
    19741 ttgacgaacg cgccccaaca ggccgccctg gccgcccttt tgagatccgc gtccttcaag
    19801 acgagcatgg cgtccttgcc gcccagctcc agtgttatgg gggtcagcct ctgcgaggcc
    19861 aaggtcatta tcctgcgccc gacgtcggca tgaccagtga atatgatgcg gtccacatcg
    19921 gatgtggcca tggcctctcc gacctgggac ccggaaccta cggccagttg gaacagnnnn
    19981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnatat ttcgggcatg cgcaagtcct
    20101 tcgtcctgct catggcccta acggtcctca tggccgcctt cataccggcg cccgccgcgg
    20161 ccgagaccga tagcggtgag gcgcttatcc cggccggggg gcatctggtc ctgcttaact
    20221 tcacggtcac tgaagatcac tgggacgatc cggcgaacgc cgggaacgtt cggtggctcg
    20281 tgtatctgga tgatgcctcg atgcaggact ctttcgacgt tttcgtgatg accgcggaca
    20341 cctatcagga atacatctcc aacggtacgt accaactggt catcgactgg ggatcgaaca
    20401 acgccggggt ggtccccgcc tataatctgg tgtatctgtt cgataaaggg gattacgtcc
    20461 tgctcatcga caataccgat gctggcggcc ttttctacac ccccgcggag ctgaaggtgc
    20521 attacgagta cgacgcgcag aacgtggatg tgcccaagga gacccgctgg gacctgttca
    20581 tcgccctcat ggtgctcgtg gccttgctgg gagtggcgtt cctgctcctc ctgaacatgt
    20641 gggtcaagca ccgcatgttg cgggtggacg aggagcgcaa gaaaagatgc tccaattgcg
    20701 ggaaggtgtc gatatccgac ggggagtact gccaatattg cggaaaggaa agatgatcac
    20761 attccccaga aggggtccga cttccgcttg atcaccagga gctgctccag ggtttccttc
    20821 tcgtccaggt tcaggtcgta gtcctgcagg ttcttgatct ccgactccag gatgtccacg
    20881 tagaggatgt cctccacgtc cagctggcga ccgacggtcg ccccttcgat ggccacggcg
    20941 atctcctgac ctacgatcgc ttccttcaga acgtcctcgc cggtacgcag ggaacggatc
    21001 ctgccgatct cccttccgtc ggaggcgacc agcttctggt tgttgcgtat gcgtcccgcc
    21061 agcaccctca cgccgactat ggccggcttg ctggcccgga acacgcagtt gggcagcacc
    21121 cggatcttgc cggggaaggc caccagggag cgcttctcca cctctgcgag gcgcttctgc
    21181 tcccctaccc atttctgata gtcatcgatg aggccgtaca ccacggcgtt caggaacacc
    21241 ttggactcgt gagtggtcag ggcgtccttg gcgtcgggaa gcatgctgac gttgaaacct
    21301 aggaccacct tgtgcagcgg atcggtgtag gcgctaacct cgatgatgtc ccgcttggag
    21361 atgtcccccg tctcgtactt gcgtatcggt atgtcggccc gcttgcactc gtacgccaac
    21421 gcttcgagcg aaccaagggc gtccgccttg atcatcaggc cgttgtcggc gacctcgatg
    21481 gttatcttgg tctcctcggc gatctccttg agcacctggt cctgattgtt cttgtaggcg
    21541 cgcagcggac cgccggccac caccccctcc agattctggc agagcaactt cacaccggcc
    21601 gcagcggtga tctccttcat gcggtcgaac ttgtcccgcg ggtcacggat ctcgtccagg
    21661 ggtttcggct tcaggatggc cttgaccttg gtcaggaggg gcttgccccg ggtgcccagg
    21721 gcgatgctgt ccccctgcct cagttccccg tcgtacaaaa tcacgtcaat ggtctgacct
    21781 aggccccgtt cctccttcac ctcgaggacg gttcctttcg ccggacctag ctcggtcttc
    21841 aggtgctctt ccaggaaacg ctgggccaat cccaccagga cgagcagcag gtccggaacg
    21901 ccttcgccgt tgcgggcgct tattgggacc agggcgatgt tcttggtgaa gtcctctatg
    21961 cgatcgtaac gttccgagga catgccctcc tcggccaacc gtccaaccac ctggtacagc
    22021 ttttctgaca gggccgcctg ggcctcctcg ctctgcgtct tctcggaaat tatgaaggga
    22081 gcggacgggt gagtgaccca gccgtccacc aggtctatct tgttcagggc gattatgaaa
    22141 ggcgtcttga agcgcttcag gatgctgatc gattccaggg tctgaggttt caggccctcg
    22201 ttgatgtcta tgaccagaat ggcgatgtcc gccagggaac cgcctcgggc gcggagggtg
    22261 gtgaaggaat gatgcccggg ggtgtcgatg aatagcagtc cgggcacggt gaacttccgg
    22321 ctgccgagca gcttggcgca gaccttgttg acgtggtcca acggaacctc cgtcgccccg
    22381 atgtgctgcg tgatccgtcc ggcctcatgg gtcatgaccg ccgttcccct gatgtagtcc
    22441 agcaggctgg tcttgccgtg gtccacgtgg cccagcacgc tgacgatggg ttgacggatg
    22501 gtcatgttca tcggatttga caatgcctat tagtatcttt ctcggagccg cgcggggtca
    22561 gagaaacatc tggagatgga aaaataaaaa agtgggtttc gggaagtcgt ttggtcctac
    22621 tcgaacagcc agaccttgtt gcaggcctcg tagctctgga gctcgtagtc gttgaagaac
    22681 agctcgatct cgcgcttcgc ggactccgag gaatcggagc cgtgaatgat gttgcggccg
    22741 gtctgctggg cgaagtcccc gcggatggtg ccgggtgcgg cctccaccgg gttggtcttg
    22801 cccatcatac cgcgcatgac ggagatgatg ttgtccccct cccagaccat tacgagcacc
    22861 ggaccggagg tcatgtagct gatgagcccg gggaagaagc ccttcccctt gtgctcaccg
    22921 taatgcctct cggccagttc gcgcgggatg cgcatgaact tcatagccac cgggcggaag
    22981 cccttggcct ccagccgaga gactatctgg cccatgagcc cgcgctgaac ggcgtccggc
    23041 ttcagcatca cgaaggtgcg ctccatcacg gggctcactc cttcgcggcc tcagccttct
    23101 tggcggccct ggccttcttc ctgctgaccg tcttcgtctt gggctcggac ttcttctcga
    23161 ccttggcctc ggcggtcgcc tcggtctcct cgaccttggc atcggacttc tccttggccg
    23221 ctatggatat gcccttcttg gtggcatagg ccttggtcca ggtggtgttc ctggccaccc
    23281 tcttgagctc gatcatgttc ttgtagcact tgttggtgca gaacatcaag gtggtcccgt
    23341 ccttcctgac gtacatcttg ccggtcccgg gttcgatctg ctctccgcag aacacgcata
    23401 aatgttgctc gaccatatga atgacctcct tacctcaggg agagcttcct cgcctctctg
    23461 gacgtctctc tgagcatcag gatgtcgccc atgcggaccg gccccatgat gttcctggtg
    23521 atgatccttc ccttgtcgcg gccatccagc acgcggacct tgacctgggt agcttccccg
    23581 gtcatgcccg tcctgccgat aacttccaca acctctgaag gaatgctatc ttcgtctgcc
    23641 atctatgaca ccctttagcc ctttatcttc ttgacctggt cgaccaaagc ctccagtatg
    23701 ggcttgccct ttccagcgtc gagtatggcg atggaggcgg tgggcttctc caatccgcag
    23761 gatgcgccca gctgagcctt gctgtcaacg tagacgtacg ggatgttcct ttcctcgcag
    23821 agcattggca tgtgcgccag tatctccggg ggctgaacgt cctcggccag aacgaccagg
    23881 actgcctctc cgcgctctac gatcttggtg acctcgttgg tgcccttctt cagcttgccg
    23941 gtgtcccggg ccagctctac gacctcatag gccttgtcct tgagttcctt gggcatctca
    24001 aatctaacga acactgcttt tgccaaactt atacctcctt ccgatgcgtt aacatcctca
    24061 ttattcatgg gctcataaga gcaggaacgc tcaaaggagt ggtcctataa aaggcttatc
    24121 caaaggcgaa aggggagtac ccagacgggt caattattcc cacggcgagc cgtccctctc
    24181 ttgattccag aatgttcacg gaccatttta ataaaatgaa attttttact gggacgggta
    24241 attgaatgaa actaccacta tccagaaaga tattcgctgg aatcggagct gtcttggcct
    24301 tcgtgggcaa cggactcgcc tactacatga tgaccgcgat gcatgaggag accgtgcttt
    24361 tcataaccac cgatgttttc acttacgagc gggacgccat aatcaccccg gtggcgatcg
    24421 gcgtgatcgg ggtcatcctg ctcctgatag cggccttgag cgaagattaa gatggaaccg
    24481 gcctagaact tggcgaacag ctggcccaag ccttcaacgg ccatcaaccc ttttacctct
    24541 atcgaataca ggtgcgtcct gcggtccacc ttgacatatc cggcgtcaac cagttttctt
    24601 atgtggaatt ggaggtgccc tttctggatc tgcagctcag aaaccatctc ggaaaagttg
    24661 cgcgagttcg tgtacagcaa ggccagtatc tttagcctga tggcattgga cagaggagac
    24721 aacaatcctt ccagactttc cggctcgatg ccggcataag cgctgtcgca cgaccttcgc
    24781 accccggggc ggccggtgtg gaagcgcagc gtctccagca tggccatctg ctccctgctc
    24841 cggtccagga ccgggagcag gaccgtcctc agatcggcgc ctatctcctc ttctgctgac
    24901 gatgcgacca ggtcgcggac ccggtccaag gcggataggg cgttgtccag atcgttcatc
    24961 tcatagcgct ccatcgcgac gtcgtataga tcggaaatct cgttcacgat gggatgggat
    25021 ggagcctgag aagcccggat caccgcgcgc acggcgtccc gattgttctc caggtaggaa
    25081 gcgccgatct gctcatggaa tgcgttctcc atcccgtcct tgcgtaacga ggtgaccgaa
    25141 cgcccgagcg agtccagacc ctgacgtagc tcctcgatct ttctcaacaa ttcgttctct
    25201 ccctcgatca tgagtaatag aatattagta cctagacata ttaaaatatt actaagtccg
    25261 atgatgcaac aggtgatgag aatgaagatc ggcgttgtgg cttgcgagag cttccggaag
    25321 gagatggacc tgctcaccga gggcgacccg gacatagtgc acaaggaata cctggagttc
    25381 ggactgcatt cctaccctca ggacctcaag atagcggtca tcgatcatgt gaacgctttg
    25441 cgaggcaagg tggacgcggt cttcctggtg tttggtacct gcaattccct gaaggacgtt
    25501 tgcaaggagc tggtcgtccc tacggtcacc atcgaggccg atgattgcgt gggcgccctc
    25561 ctgaccaacg aagagtacgc cagggagaag aaggtctgcg caggcaccct gttcgccatt
    25621 cccttcatgt ccgagatggg gacggattat ttcgagaagg agttcgaaag caagatgccg
    25681 gaccatgagc aactgggagt ggactcggaa tggtatctgg gcattctgtt cgatggctat
    25741 tccaggctcc tccacgtgga caccggggta ggcgacgcga gggcgttgca gaaaagctcc
    25801 aaggacatgg ccgaccggct caagctccgt tttgaggaac ggcaaggaac actgcaggtc
    25861 ctgaaggacc gcctacagga caccaaggag ctggcctcct ctctcacccg atcgggatag
    25921 acctcagatg aagtgcagct gctcctcgtg cggctgccta accggcctga ccttctcgaa
    25981 gttggcgcag accggctgct cgaccccgcc atagtgcagg taccacttgc ggcacagcca
    26041 ctcctgtagt ttcgccacgt cgtcattgtc catgtggcgg aaccgaccct ggaccttcag
    26101 atagtccgtc accggcagca tggtctgcgg tcgatacgtg gtccgggcct ccccgtcctc
    26161 cagttcgtac agcgtccaca tcccggtctc caccgccaac cgggatatct ccacggtcat
    26221 ggacggatcg gagcgccagc cgggtacgca tggtgtcatc acgtgcagga agcggaagcc
    26281 cttcttgctc ttggccttct ccaccttcct gatgaagtcg ttgaagtggg cgatcgaaag
    26341 cgacgccgcg tacggcgggt cgtgggcggc gatgatggcc atgaggtcct tcttgaactc
    26401 cctcttccct tcgaccttgg agcccaccgg cgtggtggtg gtccaggccc cgaagggcgt
    26461 ggccccgga
//
LOCUS       DAOPZI010000021        25550 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_1920_length_25550_cov_8.371210, whole genome shotgun sequence.
ACCESSION   DAOPZI010000021 DAOPZI010000000
VERSION     DAOPZI010000021.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 25550)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 25550)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25550
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_1920_length_25550_cov_8.371210"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..220
                     /locus_tag="PKM11_05335"
     CDS             <1..220
                     /locus_tag="PKM11_05335"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47962.1"
                     /translation="KVSIKPPTNAHTLQLLMYYIMGQHSVHKEFRDIKKLGFFNPRLN
                     QVYTLDVSTIPSWIINDVSSKVIGYKTN"
     gene            complement(1276..2211)
                     /locus_tag="PKM11_05340"
     CDS             complement(1276..2211)
                     /locus_tag="PKM11_05340"
                     /inference="COORDINATES: protein motif:HMM:NF018339.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BsuBI/PstI family type II restriction
                     endonuclease"
                     /protein_id="HNX47963.1"
                     /translation="MNKIDEAKDALIQLGLPKQQINDRSALTLLVLLNLRESTPWSVA
                     SKNTVRVHDVIQYASTVFNRTYAENSRETFRRYTLHQFIQAGIVVNNLDDPDRATNSP
                     DNNYTIADEALDLLRRYGTTSWSGALNEFHSVQEKLIERYDPRLRRVGIDVLLEEDVL
                     FTLSPGSHNELQRDIIRDFRSRFALGFKVIYVGDTAKKMLHVNKSLMETIGIPITEHD
                     KLPDIVLYNKEKQVIMLIEAVTSHGPVSPKRRLELETILSKIHMKRIYVSAFPSFTEY
                     KRYATDIAWETEVWIASDPEHMIHKNGEKFFTLYE"
     gene            complement(2212..3774)
                     /locus_tag="PKM11_05345"
     CDS             complement(2212..3774)
                     /locus_tag="PKM11_05345"
                     /inference="COORDINATES: protein motif:HMM:NF014442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HNX47964.1"
                     /translation="MMPVQNTDDEGSLVDFSSHLASVQISNHQPDERGRIGQFFTSPS
                     VAHFMANMFDISKKEIRILDPGAGTGVLTAALCEKILLNSQVQRIHIDVFENDVTVIP
                     FLEQTMIKCKERFTSRGIEASYTIIQRDFVIETSSTNNIDWQTHRFPTIEYDFIISNP
                     PYYKIHKKKGRIISSDQIVASQPNVYTVFMVLSLRLLSPEGQMVFITPRSYCSGLYYR
                     KFREWFLSKAEINWIHIFESRKQVFDKEKVLQENVIIKVSKLTTQKDYDVHISVSKDK
                     NLATLQTFQLPSSKIIYRQNGDVFIRIPSSKEELRAIEIIDHWTSNLHSMGFEISTGP
                     VVDFRTDHLCGTVDGRRKAVPLLWMNSIRNGRVHWINESGKKPQAIEDRAETSSFLLP
                     MQNYVIIKRFTSKEQIRRLDAGVLLKGDLPFDKIGLENHLNYIYRVGGELTIEDAFGI
                     ATLLNSKIVDYFFRSLNGNTQVNATEIRAMPFPPLELIRTIGKETLSNQAGSGLSPDE
                     ILEQVLEISGDD"
     gene            complement(4053..5012)
                     /locus_tag="PKM11_05350"
     CDS             complement(4053..5012)
                     /locus_tag="PKM11_05350"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47965.1"
                     /translation="MTEEMPNIYLGTRQPSESEVELAVKRKIGMGAYLCDQSGEYYHF
                     GVSTEKHLYDALSGNFKVKFVPFSPIFTVVIRKQDDGYHIEAPSRIFIESRLHNKMDG
                     FRIGSEGSLLKAIGDKIISIPQIRNQINPLFEIVSNVINYGEVAPNQFVGRGRSIDKA
                     RNYFNFLKDVDILVLEDGKYACGPVICREMDSKINVGDMYNSILAVSIQKGHHYMSEF
                     LNFTHISPFIRLGNSNYMPSFYAGELLAMSPEDLSNHHASIYGKSAIPTSKLVAWATL
                     MANAGVFKSVKKETGKPLFTGDDDIFYDYRCEWKPKARSFGVG"
     gene            complement(5027..5635)
                     /locus_tag="PKM11_05355"
     CDS             complement(5027..5635)
                     /locus_tag="PKM11_05355"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47966.1"
                     /translation="MDQIAFELLTKDWQVQDQMDSCLPSCMINITNDLQTDFQGFKIK
                     FKAKEMKSICDYRPHLGSSPDVVVKNLNNEFKRRGAPFKCAESNGTINTIDALRNIIL
                     DKDKSFPLISLSQDYFEEIGLSIEGRNPFDHVIAVLAIEDGKIWFHDPYKPFAMRSSR
                     VKTFNNHLPYVTMLKYWKETQSPNWVMWVERVAGTLDRWLVK"
     gene            complement(5636..5917)
                     /locus_tag="PKM11_05360"
     CDS             complement(5636..5917)
                     /locus_tag="PKM11_05360"
                     /inference="COORDINATES: protein motif:HMM:NF013777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HNX47967.1"
                     /translation="MSNEKGYDSILGEAYAVNILVFLYDQGSAVATEMRAVASNYNTI
                     VKVAKKLEEHGLLNISIVTSPRVTHTYRLTEKGKHVAQKLKEIEEIIGG"
     gene            6028..6180
                     /locus_tag="PKM11_05365"
     CDS             6028..6180
                     /locus_tag="PKM11_05365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47968.1"
                     /translation="MPIQLQVTKITRNGRISLGRVIPAMDAQVGDVVQIVMNDDGSFK
                     ISKVEA"
     gene            6321..7229
                     /locus_tag="PKM11_05370"
     CDS             6321..7229
                     /locus_tag="PKM11_05370"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HNX47969.1"
                     /translation="MPSYRRELRMMLSDLHKAGLQSTPKQIGEAEIEWLINERWTGLA
                     VKTKRWKLTVLNGLLKRHKNNIIAEMQLGWPRSDRVHVEWLTPEEAVILMDAAVGVER
                     IVVHLELHLGLRRCEVQRMKLKDIGQGWLQVMGKGKGEGKPRKVVWAPETYVELPAWL
                     EERERILSEARMKGEDFSEPEHLVIYRHGKRVSSYSDSGLDAVMLRAVGRSGIHKPGL
                     HHRNRRTWGRCTMEAAGKDNEKALLIVSEAYGHEDLKQTRDYLGLPLDDLDEVQRKRA
                     EYLIRIRDRMNRGLPPEKDFSIRISR"
     gene            complement(7287..7360)
                     /locus_tag="PKM11_05375"
     tRNA            complement(7287..7360)
                     /locus_tag="PKM11_05375"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7324..7326),aa:Ile,seq:cat)
     gene            7651..8214
                     /locus_tag="PKM11_05380"
     CDS             7651..8214
                     /locus_tag="PKM11_05380"
                     /inference="COORDINATES: protein motif:HMM:NF021561.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2284 domain-containing protein"
                     /protein_id="HNX47970.1"
                     /translation="MGIEGHLQALCANATMYGASKAAPVPVRNVIVDPRVNFKCQVPL
                     CKYYGRSHICPPIVMDSDRFAKVLSRYSFAILVQISLPAQELRLERERAAHDQVKKLN
                     EIVAKLERDAFHFGYRFAAGLGGGPCPLCEECSAIEGEDCRFPFQARPSMEALGIDVI
                     KTAENAGMPIELPPKDTYLWTGLVLLD"
     gene            8292..8876
                     /locus_tag="PKM11_05385"
     CDS             8292..8876
                     /locus_tag="PKM11_05385"
                     /inference="COORDINATES: protein motif:HMM:NF012655.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX47971.1"
                     /translation="MAARMKGDDRRSQILDAALVIVHTKGIHSLTLREIADRVGVSEA
                     ALFRHFKGKEDIVDSLASMVFEENQFFPRGEGPWEALENMLTWQLEKFQKNPMHTSIL
                     FQEDIFREFPSVKERFDLRRSSRSSLISQLIREGKSSNVFTSDVDPDAFSLLFMGGLR
                     LAVLEWRHSNFSYDLREKAPPLLRMLRKCLEAER"
     gene            8873..9634
                     /locus_tag="PKM11_05390"
     CDS             8873..9634
                     /locus_tag="PKM11_05390"
                     /inference="COORDINATES: protein motif:HMM:NF024211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX47972.1"
                     /translation="MKLELAMVLGIIYTAVMVPAISYLLYKGKLRKELGWVLLVISAL
                     LGFAYFAPMFPWQLQLLMLGKLPQANLPMVALVTSIVILSSLLVGRVFCGYVCPPGAL
                     QELAYLAPIKKIKVPSSITVKVRLVVFVAMLVLAVVFSFNLTKVLGLPAFFQLILGPG
                     LVIFLAIIISSTVVYRPFCRFVCPFGALSSLLSWMSVYGVRRNSNCVDCGRCEKVCPP
                     QVLKGRAGSECYLCGRCLATCHKDALKYSKVEVKK"
     gene            9631..9969
                     /locus_tag="PKM11_05395"
     CDS             9631..9969
                     /locus_tag="PKM11_05395"
                     /inference="COORDINATES: protein motif:HMM:NF019498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HNX47973.1"
                     /translation="MKAAKYTDFPEKDTPHKVSVRMIYDHDHGQAVVISLKKGETLKK
                     HITPVDVMFYVLEGTGKVEIGDEVLEVSRDMVIESPARIPHRLFNESSPEFRFLVLKM
                     PKPVDKTKVL"
     gene            9978..10334
                     /locus_tag="PKM11_05400"
     CDS             9978..10334
                     /locus_tag="PKM11_05400"
                     /inference="COORDINATES: protein motif:HMM:NF019498.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HNX47974.1"
                     /translation="MAMEIMNPDGVKKEDLRGKVMVSKDLVSYQDGAVVSRTLISKSV
                     GTVTVFSFDEGQGLSEHTAPYDAMVEILDGEADITISGKTQRVKAGEMIIMPANQPHA
                     LHGVKAFKMMLIMIRA"
     gene            complement(10370..10442)
                     /locus_tag="PKM11_05405"
     tRNA            complement(10370..10442)
                     /locus_tag="PKM11_05405"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10407..10409),aa:Asn,seq:gtt)
     gene            complement(10473..10808)
                     /locus_tag="PKM11_05410"
     CDS             complement(10473..10808)
                     /locus_tag="PKM11_05410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47975.1"
                     /translation="MKGHSVLTSKIEAEVELLERHVVMLNAIKKHEPIGIIRLSELLD
                     IPQHKVRYSLRILEQEGLINPSPEGAVTTEKLDEFYERVVDILDRMEVTVGKLKGELE
                     LEFRKNIKV"
     gene            10937..11665
                     /locus_tag="PKM11_05415"
     CDS             10937..11665
                     /locus_tag="PKM11_05415"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX47976.1"
                     /translation="MPAIVVDGLTKRYGEFVALDQATFTVDEGAFFGCFGPNGAGKST
                     LLKILTGQIPATGGTAEVLGLDPAKNAMEVKRRIGIVPEVESPPSYLTASEFLRFAGT
                     LHEVQSLDGRIERWLTFFDLKGAEGTLCRDLSKGMRQKVMLAAAFIHEPKLLFLDEPF
                     INLDPIYQRKLRDYLLDLREDGRTVFLCSHILDVAQRIVQEMIIMDRGKVVLKDKVSN
                     ALVGGEDLETLFLRLVGGGNGLAP"
     gene            11640..13106
                     /locus_tag="PKM11_05420"
     CDS             11640..13106
                     /locus_tag="PKM11_05420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47977.1"
                     /translation="MGGTASLLRLMLTEEYRMHVKYSSRQMFLSLPLYIFFFTALFTY
                     GLDILTGDLRLWDLMLMAYGGIYIYGLSVGAFGVLGQSYLERRYGKDNFLISMPFLLP
                     VSFRKVFLGMYLRDVIFYSALMLLPAFGGMALGAALSSHSLISVLVIFIGLLVTFLYG
                     MSTSFLISVLFAIDRRIFLLAVGGLIALVAGYGLTGLYGLDLIIPSLGYQLKALPFPA
                     DWPLALFYLAICAALSVAFLALSLMLVRPGRSVMVGTHREMFLQHLKVFSRFPSRALL
                     AKEFVDIRRSGLTVRMIFAYVVPLVFLSFTTYYVNHGLNIPVGFNAVFYGAMVGFFGV
                     LLYSWMTNTDLNDYYETLPVRVPQIIKVKLMAYFLLTTGVSTLFVIGISMLNDEWQLL
                     WLALVVLYCTTAYMILATAYLTGLNTNSFFFNPTVLTKFTAISLLPDLLLTILSFSLQ
                     SGAWWALAGILGVCGVLLILSLYFYRGIEKKWGGASFL"
     gene            13160..13723
                     /locus_tag="PKM11_05425"
     CDS             13160..13723
                     /locus_tag="PKM11_05425"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47978.1"
                     /translation="MDWHRVRRLIHVLAPLLCIYYIVPDPVVPGVPNDQVILLLMLIV
                     LVLDTIRLIARFKVPILHSYEDDRPSAPAFFAVSAAIALLFFPVEITLPVLLGMGVVD
                     PLVGELRMRKSDLNPVLPMAVYFFILLIGLGYFYGLSFLVLLSCLLVAPIALFLESRR
                     LPYIDDDMILVLVPLFLLALMFGQLPF"
     gene            complement(13743..13889)
                     /locus_tag="PKM11_05430"
     CDS             complement(13743..13889)
                     /locus_tag="PKM11_05430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47979.1"
                     /translation="MSKIIYQCLVCNKVHQTLDGAENCHKGPTQTVEQGLTGFSKRKG
                     LIGN"
     gene            14087..14584
                     /locus_tag="PKM11_05435"
     CDS             14087..14584
                     /locus_tag="PKM11_05435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HNX47980.1"
                     /translation="MNKIKVINEPSELVSMLRAVDTPVKRDVLKEVTLEWRTVKEIEE
                     KYGAEGKEALAFFEKMKLVETRWQPSGGNRPDKAYHTYYNSFHINAQWPVYEISDVLY
                     AAMMPDEEFEEIENNILEQVGKEGRFAGDVAENLGMTATMLKSLVKRSIKMDYRGHRL
                     EMVKE"
     gene            14586..15107
                     /locus_tag="PKM11_05440"
     CDS             14586..15107
                     /locus_tag="PKM11_05440"
                     /EC_number="2.1.1.206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(56)-2'-O)-methyltransferase"
                     /protein_id="HNX47981.1"
                     /translation="MPEITVLRLGHRPERDKRITTHVALTARAFGARRIIVSTKDPVL
                     EESINDVVKRFGGDFEITTGVNWRRFLQDFQGTVVHLTMYGLPVDEAAPNVPDGNVLV
                     VVGAEKVPPEVYQRADLNVAVGNQPHSEVAALAILLDRVFQGRMLQRDYQGAQIKVLP
                     CERGKNVVELSKH"
     gene            15124..15660
                     /locus_tag="PKM11_05445"
     CDS             15124..15660
                     /locus_tag="PKM11_05445"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HNX47982.1"
                     /translation="MREEKLSTVVVRHCCVVNLVALSIARRCGADLELVNAASLLHDI
                     GRSRTHGVQHVAEGVRIAKEHQLPDDLVNCIGRHIASGFTSEEAEALGLTKGDYMPVT
                     LEDKVVNFADNLVSDRSIKTVAQAVERMRSKGFELTADRMLAMGQEISKLCGEDIDTI
                     LQKDQVREAAAALCDKMA"
     gene            15770..16699
                     /locus_tag="PKM11_05450"
     CDS             15770..16699
                     /locus_tag="PKM11_05450"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: protein motif:HMM:NF005146.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transaminase"
                     /protein_id="HNX47983.1"
                     /translation="MSEKKIMMWMNGKLIEQEKVLLPFMTHALHYGSGVFEGIRIYET
                     PKGKAVFRLREHMVRFLDSAKVMCMTHPYTVDELVEATRLAVRNAADNADYIRPLMWY
                     GENDENRIVLNPFKFKVNTAIACAHMGAYLGKDNMENGAKVITSSWTKPANTSTSLQA
                     KICGNYVNSILAKIESNQLGADECLMLNTNGTVAEGPGENIFMIKNGKVYTPPLASGV
                     LEGITKDSVSTIAKDKGYQVIEKEITRSEIYMCDEFFMTGTAAEVTPIRSLDQRVIGT
                     GKRGPITKDLQEAFFEAARGKDPKYSHWLTPVN"
     gene            16768..17670
                     /locus_tag="PKM11_05455"
     CDS             16768..17670
                     /locus_tag="PKM11_05455"
                     /inference="COORDINATES: protein motif:HMM:TIGR02175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HNX47984.1"
                     /translation="MYEIRFHGRGGQGAVMAAQTIAEAAILEGKQAQAFPFFGAERRG
                     APVMAFARIDDKRICDRTQVSEPDLLVVMDESLLEIEPVASGLKKGGCAVVNSALPPS
                     EIDLGVVTRCVSVDATSIALEMLKAPIVNTSILGAMARADDFVKLESIQQAIMNRFGE
                     KLGEKAGRLNAEAAQAAYERSLEGTCKGERKVQRKNAWLPTWQETPPGVALPKTTKAG
                     MAVGPGSMAQNLTGSWGVSNPVYDETKCIRCQRCWFICPEGCIRRSDDGALQFDIRYC
                     KGCGLCVKVCPKDAIHMKRKGMKA"
     gene            17667..18842
                     /locus_tag="PKM11_05460"
     CDS             17667..18842
                     /locus_tag="PKM11_05460"
                     /inference="COORDINATES: protein motif:HMM:NF013974.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase C-terminal domain-containing
                     protein"
                     /protein_id="HNX47985.1"
                     /translation="MRSVRALTGNAAAAYGVKLCRPEVIPNYPITPQTIIIEQLADFI
                     NDGELDADFIPADSEHSAMSMAIGAAATGVRTFTATASHGLALMHEMLYVPPQVRLPI
                     LLVNVNRSLGAGSGIWVEYNDSMAERDSGWMQAYAEDSQEVLDMVIQAYRIAEDPRVV
                     LPFMLCLDGFILSHTVERVEVPGQEEVDSFLPKFKPLNRLDPKDPMSINIAVSPAHSM
                     EMRYQLDRQMEGARKVISEVDDLFAKGFGRRYGGLIDTYRMEDAETALITLGTATSTA
                     RVAVDELRAEGRKVGLIKLRFMRPFPHDEIKNAVRNIKALGVFDRSISANRFGPVFTE
                     VRNSLYVSGIPITDHIAGIGGRDLKVATFKEMFEVLEKSASGQKVRDCTWHGLRGEM"
     gene            18842..19798
                     /locus_tag="PKM11_05465"
     CDS             18842..19798
                     /locus_tag="PKM11_05465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="HNX47986.1"
                     /translation="MDRKMNIRNMPSEDHLLCGQGACAGCGVAIAVKNIMRILGENTT
                     VYVPASCLLVFGGGMYPHSAFDVPFFYSAFENTGAVISGIKAGYRRQGKDVTVIGIAG
                     DGGTFDIGLQALAGAAERNEDVIYVCVDNEAYMNTGTQRSGSTPFGAWTTTTPVGKKI
                     KGKQGFKKDLMSVVTSQDIAYAATLSIAHMNDFVQKVEKAKNLKGFRFLHVMTPCTSG
                     WKSDPSATFDLANMAVETGMWSLYEVMDGEVNITYRPKEMRPVTEYLKLQGRFKHMSK
                     EDVDTLQTWICKKWNKRYCPIAPPMDGKEEDLAYDGDECEGV"
     gene            complement(19803..21383)
                     /locus_tag="PKM11_05470"
     CDS             complement(19803..21383)
                     /locus_tag="PKM11_05470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HNX47987.1"
                     /translation="MVDVLTLAAFTALYVGILLAISFIAYRRTKKGEDYLLAGRKVHP
                     AIIGLSYGSTFISTSAIVGFGGVAAQLGMGIIWLTVLCIGVGVLIAFIVYGKRTRRIG
                     QRLGAVTLPDLLAKRYNSNFLQYGTSVIILASMPLYSSAVLIGGSRFIETTLGIDYTT
                     ALLGFALITALYVVFGGILAVMYTDAFQGGIMVFGMVAILIITYVTLGGVTGAHQELT
                     DMASLVPAGLAGQGMTGWTSMPELGSPIWFTLITTIVMGVGIGVLAQPQLVVRYMTAK
                     DDRSLNRAIPVGGLFILLCTGVAFTVGALTNVYFYRENGVISTSMVSGNIDQIIPLFI
                     NTAMPDVVVILFMLTLLAAAMSTLSALFHSMGSAAGHDLWTHLGSCRLMPSSIRKERT
                     GDCSSLRANRTGTTIMIAVSIGLAFLMPGSIIARATAMFMGLSAAAFLPLFTLAIFSE
                     RPSVLAAKLSLAVGTGTWFLWTAFVHIKESSVLGISKALFGTDAVLASPWTVVDPLVI
                     ALPASVIALIIGVLLDKR"
     gene            complement(21376..21528)
                     /locus_tag="PKM11_05475"
     CDS             complement(21376..21528)
                     /locus_tag="PKM11_05475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47988.1"
                     /translation="MMREDRNGGRGMLGIDDPQIIVGYALAIGLGLMCLAYGILHWND
                     GGENGG"
     gene            complement(21649..23244)
                     /locus_tag="PKM11_05480"
     CDS             complement(21649..23244)
                     /locus_tag="PKM11_05480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HNX47989.1"
                     /translation="MVNQLYFWAATAVYAVVIFYLAWLGYKKTRSNADYMLAGRNVHP
                     VILGLSYGATFISTSAIVGFGGYAAKLGMGIIWLVMLNISVGVLIAFIVFGKPTRRIG
                     KRLGALTFPDLLGKVYKSNFMQYVTGLIIIVGMPLYSSAVLIGGGRFIEEVLDVPYLW
                     AIIGLTAITAAYVVFGGLVAVMYTDALQGSLMIFGMSAIMIFTLSAVGGFDGFQSLTD
                     MSHLVPAGLASTGMTGWTSFPELGSATWYTLVTTVIMGVGIGVLAQPQLAVRFMTAKD
                     GKSLNRAIPVGAIFILITTGVAYTMGALTNVYFYNNFGKISTQMTGNIDNIVPLFIDT
                     AMPEWLVVMFVLVLLAAAMSTMSSLFHVMGTAAGHDIWVHVRRARFFPSRMRGSDEDA
                     SKLRVNKIGTFVMIAASLGLAFIMPGDIIARATAMFMGLCAAAFLPAYTVAVFVKNPS
                     RLGAIASLLTGSIVWAVWTVFVHKAESSVLRLSEILTGSPSVLDFPWTVVDSLFIALP
                     LSIAALIIGTMIERRRSSAPAEA"
     gene            complement(23452..24750)
                     /locus_tag="PKM11_05485"
     CDS             complement(23452..24750)
                     /locus_tag="PKM11_05485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HNX47990.1"
                     /translation="MSYWNPVEVMPVPELKALQLKQLKMLVYKLYTFSPFYRQKMKEA
                     GVTPEDIQELDDVRKLPFMTKKDLRDGYPDKLFLASPREVVRYHASSGTTGKPTIVGY
                     TQNDIENWSESVARGLVSAGVGTDDVLQVCYTYGLFSGGLGLHYGAEKVGAAVVPAST
                     GNTERQIDLVRDLDVTVIAATPSYLLHMGEVAAKMGVDIRKDTKLRLGILGAEPWSER
                     MRDRIFERLGIKAIDIYGTSELSGPLWCECSEQNGIHVWGDITLVEVLDPETDEPVPP
                     GGKGELVVTMLLKEALPIVRYRTGDITTVSEEVCACGRTHPRIGRIQGRVDDMIIIRG
                     INVFPSQVEYSLMQHPEVGNEFQIVVDRKGALDSLLVKVELRPEAFGDRVFELDAIKD
                     RLTHKLRDALNVGVSVEIVEPGSLPRFEGKAKRVVDRRVF"
     gene            complement(24781..25212)
                     /locus_tag="PKM11_05490"
     CDS             complement(24781..25212)
                     /locus_tag="PKM11_05490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase"
                     /protein_id="HNX47991.1"
                     /translation="MSENDKYRIKQLSIFSENRPNRLGAVAKVLKEGKINILGFSIAE
                     GAGYGVIRVLVDRPDIARDLLIKDGFVVKFTEVLAIQMQDTPGGLFDLTDQMKDINIE
                     YGYGYRNPPYAVLIVRVEEIEQGISSLLAGGLRLLDNVTFH"
     gene            complement(25212..>25550)
                     /locus_tag="PKM11_05495"
     CDS             complement(25212..>25550)
                     /locus_tag="PKM11_05495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HNX47992.1"
                     /translation="RIQGRVDDMIIIRGINVFPSQVEHSLMQHSEVGNEFQLVVDRKG
                     HLDTMLVRAELKPEAFTDNIIELNALRERISNRLKNVLNVSANVELVQPGTLPRFEGK
                     AKRVVDRREY"
BASE COUNT         5831 a         6908 c         7042 g         5769 t
ORIGIN      
        1 taaagtctct attaagccgc cgaccaatgc tcacactttg caactcttga tgtactacat
       61 catggggcaa cattccgttc acaaggaatt tcgtgatatc aaaaagcttg gcttttttaa
      121 tcctcgcctg aatcaggtct atacgttgga tgtatccaca ataccatcct ggatcatcaa
      181 tgatgtatcg tccaaggtga tcggttacaa aaccaattaa tcgaaagtaa gttgggtacg
      241 ccagtaccca ctcgtccttt ctgaaaatat ggggagaggg gaccgttcga gcacaatcga
      301 ttttacggtt aaggataccc ctcttggagt aaacataatc cccctaaaag ctaaaatccg
      361 gataagaaat cttaaccaga tattgagtcg cgttattaac caataatgtt taaatactta
      421 cttgccagag ccaacgttta aataagtacg ctcaaatagt tgtggcatgg acccaataaa
      481 agtggtctac ggcggattga aaatcgcaat ccccgcctgg gtaatatatg ccctaatcgc
      541 ggccttgtct tgaaccatta gccgcgatca ggaagcctca aaccctttca atttttttct
      601 actcggatta tgagactggt tccgatttca tcttataact atttataact tgctcatttt
      661 tcaattattg aatttttttt actccatcaa ccagtatact ttacgctcgt atatccgtta
      721 ctccattgtt acggcgttag ggattgggtt tcacagatca gcaaggcaat ccttgaggaa
      781 ttcaactatt cgttgaattc gggatcgatc gtgtatttcc ttttttcaat cagaattgaa
      841 taatctgcca tgaaaagagg cttagaatcc tcaaattagg tttggaaaat gtgtaaacaa
      901 tcaggggtga aagacaaaat tcggcctttc atgaacgacc cagatgcggt aatacagtac
      961 aacatgagtg attgggctta gcggaggggg agggtgaagg tgttctacta acgtagctta
     1021 tagggtggac ttacgagtat tgcatgtgag ggatacggaa ttcggaagac ggtgcaacaa
     1081 gaggcggtgg ggcttaaagc gcaccggggg aagatgatta ctattagggg tgatatctcc
     1141 gctatcgaac gttgaggaga cgtttttctg aggtttaatc cgctctctta aatcatagac
     1201 agtgaaattt tggaaaaagg tccgtgaatt tggcagtatt cgcaattttt ttaataaatt
     1261 tcacgaggct aaaattcatt cgtatagagt aaagaacttc tccccattct tgtgaatcat
     1321 gtgttctgga tcactagcta tccacacttc tgtctcccag gcaatgtcgg tcgcataccg
     1381 tttatattct gtgaaggacg gaaacgcgct tacatagatt ctcttcatat gaattttaga
     1441 taaaatcgtt tccagttcta accgcctctt aggagataca ggcccatgcg atgtcactgc
     1501 ctcgattaac ataatgacct gtttttcttt gttgtaaagg actatatcag gcagtttatc
     1561 atgttctgtt atgggaatcc ctatggtttc catcaaggat ttattaacgt ggagcatttt
     1621 ttttgctgta tcccccacat aaatcacctt gaaacccagg gcgaatctgc ttctaaaatc
     1681 gcgaatgata tctcgttgca attcgttatg ggaaccaggt gagagagtga ataatacatc
     1741 ttcttcaagt agcacatcaa tccctactcg ccgaagtctc ggatcatatc tttctatgag
     1801 tttttcctga acgctgtgga attcgttaag ggcaccgctc cagctcgtag tcccatatct
     1861 cctaagtaaa tccaaagctt catccgcgat agtatagttg ttgtcaggac tatttgtcgc
     1921 tctgtccgga tcatcgagat tattgacaac gattccagcc tgaatgaact gatgaagagt
     1981 atatctccgg aatgtttctc tagaattctc agcatatgtg cgattaaaaa cagtgctggc
     2041 atattgaata acatcgtgga ccctcaccgt gttcttacta gcaacagacc agggggtact
     2101 ttccctcaaa ttcaacaata ccaacaaagt tagtgcactt ctatcattga tttgctgctt
     2161 tggcaaccct aattgtatga gagcatcctt agcttcgtca atcttgttca tctaatcatc
     2221 accactaatc tccaggacct gttcaagtat ctcatcggga gataaaccgc ttccggcttg
     2281 attacttaac gtctcctttc caatcgtcct aatgagttct agcggaggaa acggcatcgc
     2341 cctaatttca gtggcgttca cttgggtatt cccatttaat gatcgaaaaa agtagtcaac
     2401 aatcttagaa ttgagcaatg tcgcaattcc aaaagcatcc tcaatggtga gttccccgcc
     2461 gacacgataa atataattca aatgattctc cagcccaatc ttgtcaaacg gtaaatcgcc
     2521 ctttagtaag acaccagcat caagtctcct tatctgctcc ttagaggtga aacgctttat
     2581 aatcacataa ttttgcatgg gtagcagaaa agaacttgtc tcagctctat cttcgatagc
     2641 ctgtggtttt ttaccagatt cgttgatcca atggacgcga ccattacgaa tgctattcat
     2701 ccagagaagc ggtaccgcct tcctacgccc atcaaccgta ccgcaaagat ggtcagttct
     2761 aaaatcaacc accgggccgg ttgaaatttc gaaccccatt gaatgaagat ttgatgtcca
     2821 gtgatcaatt atttcaatcg ctcttaattc ctctttagat gaaggtatcc ttatgaacac
     2881 gtctccattc tggcgataaa taattttaga tgagggcaat tgaaaagttt gtagggttgc
     2941 aagatttttg tctttactga ccgagatatg aacgtcatag tctttttggg ttgtaagttt
     3001 agatacctta ataatgacgt tctcctgaag gactttttcc ttatcaaaaa cttgtttcct
     3061 ggattcgaaa atatgtatcc agtttatttc cgctttcgaa aggaaccatt ctctgaattt
     3121 cctgtaataa agtccggagc aataactccg tggggttatg aacaccatct gtccctcagg
     3181 tgatagcaat cgtaatgata gtaccataaa aaccgtgtaa acattaggtt ggcttgcaac
     3241 gatttgatcg gatgaaatta ttcgtccttt ttttttatga attttataat atggtggatt
     3301 ggatattatg aaatcgtatt caattgttgg gaatcgatgt gtttgccaat caatattatt
     3361 ggtagagcta gtttcaatca caaagtccct ctgaattatt gtgtaagaag cttcgatccc
     3421 ccgcgatgtg aaccgttctt tacattttat catggtttgt tcaagaaatg ggatgacagt
     3481 aacatcgttc tcaaacacgt ctatgtggat gcgctggact tgactattaa gaagaatttt
     3541 ctcacaaaga gcggcggtta acacgccggt ccctgcgcct ggatcgagga ttctaatttc
     3601 cttcttacta atatcaaaca tgttcgccat aaaatgggcg acgcttggtg aggtgaagaa
     3661 ctgcccgata cgccctcttt catcaggttg atgattagat atttgaactg atgccaaatg
     3721 agaagaaaaa tcaaccagcg agccttcatc atcggtgttt tgaacaggca tcatcggatc
     3781 gggctaataa gggtgattcc attatatcaa ttaccaacca gagagggtta aaaatgaaat
     3841 gcccagttcc tttcgacaat catatgttcc caactttcac caacccccta ctattctagg
     3901 tgggttaagt ggttggtggg tattggatag gaaaaaatcc ctgggctgct tattgtggta
     3961 aaggagagta ataatgagga atggacaccg taatcggaac tggttgggat ttgaggttgg
     4021 gggtgtctat gcagtcagtg ctcatcaaga aatcaaccaa ccccgaagga tctagccttg
     4081 ggtttccatt cacaacgata atcatagaaa atatcatcat caccggtgaa tagaggtttt
     4141 cccgtctctt ttttaactga cttgaagaca ccggcatttg ccatcaatgt agcccaagcc
     4201 actagcttgg aagtggggat tgccgatttt ccataaattg aggcatggtg gttagacagg
     4261 tcctctgggg acatggccag aagttctccc gcatagaatg atggcatgta attcgaattc
     4321 ccaaggcgga tgaatggtga gatgtgagta aaattcaaga actctgacat atagtgatga
     4381 cccttctgta tagaaacggc caggatagag ttatacatat cacccacatt tatttttgag
     4441 tccatctcac gacatattac tggaccacat gcatatttac catcctctaa taccagtatg
     4501 tccacatctt taaggaaatt aaaataattc ctggccttat cgattgatcg gcctcggccg
     4561 acaaactgat ttggtgcgac ctctccataa ttgataacat tgctaacgat ctcaaagaga
     4621 gggttaatct ggttcctaat ttgtggtatc gagataatct tatctccgat tgccttcaac
     4681 aaagaacctt cggatccaat acggaaacca tccattttgt tatgcaatct tgattcgata
     4741 aaaattcggc tcggagcctc aatgtggtaa ccatcgtctt gttttctaat cacaactgtg
     4801 aaaattggtg agaatgggac aaatttaacc ttaaaatttc ctgaaagcgc atcatacagg
     4861 tgcttctcag tggacacgcc aaaatgatag tattctcctg attggtcgca aaggtatgcg
     4921 cccataccta tctttctttt aacagccagc tccacttctg attcggaagg ttgcctggtg
     4981 ccaagatata tgtttggcat ttcttctgtc atagattccg ttgagctcat tttactaacc
     5041 acctatcaag ggtccctgcc accctctcca cccacatcac ccagttcggc gattgagttt
     5101 ctttccaata tttcagcatt gttacatacg gaagatgatt attgaaagtt tttaccctac
     5161 tcgacctcat tgcgaatggt ttgtaaggat cgtgaaacca tattttacca tcttctattg
     5221 ctaataccgc aatgacatga tcaaacgggt tccttccttc aattgacaag ccaatctctt
     5281 cgaagtaatc ctgactcaaa gagatcagtg gaaatgattt atccttatcc aatatgatgt
     5341 ttctcaatgc atctattgtg ttgatagttc cgttcgattc tgcacattta aagggggcac
     5401 cccttctctt gaattcattg ttaaggtttt tcactaccac atcaggcgat gaaccaaggt
     5461 gtgggcgata gtcgcaaatt gatttcatct ccttggcttt gaatttaatt ttaaaacctt
     5521 ggaaatcggt ttgcaaatcg tttgtaatgt ttatcatgca cgaaggtaaa caactgtcca
     5581 tctggtcttg gacctgccaa tccttcgtta gtaattcgaa tgctatctga tccactcaac
     5641 cacctataat ctcctcgatc tccttcaatt tctgagccac atgcttgcct ttctcagtaa
     5701 gacgatatgt atgagtcact cgagggctgg ttacgatgga aatattcaac aatccgtgtt
     5761 cttccaattt cttcgctact ttaacaatgg tgttataatt gctggccacc gccctcatct
     5821 ctgtggcaac ggcggaccct tgatcataga ggaaaacgag gatattgaca gcatacgctt
     5881 cacccagtat cgaatcgtac cccttttcat tactcattac taatccgttc ttaatttatt
     5941 actgatatct aatagatatt gtaaccgatt accaatcggt aaccttaagt accccaataa
     6001 ccaattacca attagcaagg tgaatcaatg ccaatccaac tccaagtgac gaagatcacc
     6061 aggaacggcc gtatatcctt gggcagggtc atcccggcca tggacgccca agtcggcgac
     6121 gtagtccaga tcgtgatgaa cgatgacggg tccttcaaga tttccaaggt ggaagcctga
     6181 acgtgtgcgt gatacgccgc gaggtgcagc cgagatgaaa ggagaggctc tggatgacgg
     6241 atgggaagta ttacagaaac gagattatag agaagcatct ggaccttatg aacaggcggg
     6301 ggcgcctcaa gggttctcaa gtgccgtcct acaggcgcga gctccgcatg atgctgagcg
     6361 accttcacaa ggccgggctg caatcgactc ccaagcagat cggggaggcc gagatagagt
     6421 ggttaataaa cgagcgatgg accggcctgg ccgtcaagac caagcgctgg aagctgacag
     6481 tgctcaacgg cctgctgaag aggcacaaaa acaacatcat cgcggaaatg cagctgggat
     6541 ggccccggtc agaccgcgtg catgtggaat ggctgacgcc ggaggaagca gtgatcctga
     6601 tggacgctgc tgtgggtgtg gagcgcatcg tcgttcacct ggagctccac cttggtctcc
     6661 gtcgttgcga ggtacagcgc atgaagctca aggacatcgg ccaagggtgg ttgcaggtca
     6721 tggggaaggg gaagggggaa ggcaagcctc ggaaggtcgt atgggctccg gaaacgtatg
     6781 tagagctccc agcctggcta gaagagcggg agaggatact gagcgaagcc cggatgaagg
     6841 gggaggactt ctcggagccg gagcacctgg tgatctaccg gcacggaaaa agagtatcat
     6901 cctactcgga cagcggcctg gatgcggtga tgctgagggc cgtgggacga tcgggaatac
     6961 acaagcccgg gcttcaccac cgcaaccgca ggacctgggg acggtgcacc atggaagcgg
     7021 ccggcaagga caacgagaag gcattgctga tcgtctccga agcgtacgga cacgaggacc
     7081 tcaagcagac cagggattat ctcgggctgc cgctggacga cctcgacgag gtgcagcgga
     7141 agagggcgga gtatctgata cggatcagag accgcatgaa caggggcctg ccgccggaga
     7201 aggacttctc gataaggatc tcaagatgag ccggaggtgc tcgaaagcgc cccgatttga
     7261 aaaaacggat gagccaggaa gtgtgatggg cccggtcgga tttgaaccga cgaccaaccg
     7321 gttatgagcc ggccgctcca ccggactaag ctacggaccc gtgatgggtt caggttaaag
     7381 cagggcgcaa tataaaattg ttgtttaatc agaccagcct cgattccggc atctgattta
     7441 cattaccaat tgtttatttc cgggccaatt cgttttccgt cattaagggt tggacgcacc
     7501 gctctggagg ataaaaaatg gaaatagatt tccgactggc atctccacca acgtgctggt
     7561 gctgggtgcc accggctcca tcatcggtct gatcgagggg gcaggcaacc gttttaggtt
     7621 cgttggacgt tatggatgtg agggaggatc atggggatag aggggcatct tcaggcgctg
     7681 tgcgccaacg cgacgatgta tggggcgagc aaggcggcac cggtgccagt gcggaacgta
     7741 atcgtcgacc ccagggtcaa cttcaagtgc caggtccctc tgtgcaagta ctacggccgc
     7801 agccacatct gccctccgat agttatggac tcagacaggt tcgccaaggt gctgtccaga
     7861 tacagcttcg ccatactggt gcagatatcg ttgccggcgc aggaattgag gctggaaagg
     7921 gagagggcgg cgcacgacca ggtcaaaaag ctcaatgaga tagtggccaa gttggagagg
     7981 gacgccttcc acttcggata ccgcttcgcc gccgggctag gcggcggtcc gtgtccgtta
     8041 tgtgaggagt gcagcgccat cgaaggcgag gattgccgct tcccgttcca ggcccggcct
     8101 tccatggagg cgctcggcat tgacgtgatc aagaccgccg agaacgctgg aatgcctatc
     8161 gaactgccgc cgaaggacac ctatctatgg acaggcctcg tccttctgga ttgacgtcat
     8221 tttcttgttc tagaaaatga tttatacctt taccatcaat gttagttatt gataactaac
     8281 aaggtatgca catggccgcc agaatgaagg gggatgaccg caggtcgcag atactggacg
     8341 cagctctggt cattgtccat accaaaggca tccattccct gaccttacga gagatagccg
     8401 accgagtggg agtgagcgag gccgctctct tccgtcattt caagggaaag gaggacatag
     8461 tggattccct ggccagcatg gtgttcgagg agaaccagtt cttcccccga ggtgaagggc
     8521 cgtgggaggc cttggagaac atgctcacct ggcagctgga gaagtttcaa aagaatccga
     8581 tgcacacttc catactgttc caagaggaca tcttccggga gttcccgtcg gtcaaggagc
     8641 gcttcgatct ccggcgctcc tctcgttcct cgctaatctc ccagctgatc cgggaaggga
     8701 agagttccaa cgtttttacg tcggatgtgg acccggatgc tttctccctg ctcttcatgg
     8761 gcgggttgcg cctggcggtc ctggagtggc ggcattccaa cttctcctat gacctgcggg
     8821 agaaggcacc gcccctgctt aggatgctga ggaaatgtct ggaggctgaa agatgaaatt
     8881 ggagttggcg atggtcctgg gaatcatcta caccgcggta atggttcctg cgatcagtta
     8941 tcttctgtat aagggcaagc taaggaagga gctcggctgg gtgctgttgg tcatatcggc
     9001 gctgctgggc ttcgcctact tcgcgccgat gttcccctgg cagctgcagc tgctcatgct
     9061 cggaaagctt ccgcaggcga acctgccgat ggtggccctg gtcacctcga tcgtcatact
     9121 gtcatcgttg ttggtcgggc gggtgttctg cggatacgtg tgccctcccg gggccttaca
     9181 ggaactagcc tacctggcgc cgatcaaaaa gataaaagtg cccagctcca tcaccgtcaa
     9241 ggtacgcttg gtcgtgttcg tggccatgct ggtcctggcc gtggtgttct cgttcaacct
     9301 aaccaaagtg ctgggcctac cggctttctt ccagctgatt ctcggtcccg gcctggtgat
     9361 cttcctggcg ataatcatct catcaacggt ggtgtaccgc ccattctgca ggttcgtctg
     9421 ccccttcggg gcgctgtcat cactgctctc ctggatgagc gtctatggcg taagaaggaa
     9481 ctccaactgc gttgattgcg gcagatgcga gaaggtatgt ccgccccagg tgctgaaagg
     9541 aagggcggga tcggaatgct acctgtgcgg caggtgccta gcaacatgtc ataaggacgc
     9601 attgaaatac tctaaggttg aggtgaagaa atgaaagcag cgaagtacac ggatttcccg
     9661 gagaaggaca cgccgcacaa ggtcagcgtg cgcatgatat acgaccacga tcacggccag
     9721 gcggtggtga tatcgctcaa gaagggcgag accctcaaga agcacatcac cccggtggac
     9781 gtcatgttct acgtgctgga agggaccgga aaggtcgaga tcggcgacga ggtgctggag
     9841 gtcagcaggg acatggtcat cgaatcccct gcccgcatac cgcaccgcct gttcaacgag
     9901 tcatcgccgg agtttcgctt cctggtgctg aagatgccca agccggtcga caagaccaag
     9961 gtgctgtgag ggatgatatg gcgatggaga taatgaaccc ggacggggtc aaaaaggagg
    10021 acctcagggg aaaggtgatg gtgtccaagg acctcgtttc ataccaggac ggggcggtcg
    10081 tgagccgcac gctcataagc aagagcgtgg gaaccgtcac cgtcttctcc ttcgacgagg
    10141 gccaggggct gagcgagcat accgcgccct acgacgccat ggtggagatc cttgacgggg
    10201 aggcggacat aaccatatcc ggtaaaacgc agagggtgaa ggccggggag atgatcatca
    10261 tgcccgccaa ccagcctcat gccctgcacg gggtcaaggc cttcaagatg atgctgataa
    10321 tgatcagggc ctgaaacaaa cctttttatt aaaatttatg aagggaaggc gccgtcgagc
    10381 gggatcgaac cgctgacctt atgattaaca gtcatacgct ctaccgactg agctacgacg
    10441 gcctgctgag cctgtagaac agaggtcgca tattaaactt ttatgttctt cctgaactcc
    10501 agttccagct cgcctttcag ctttcctacg gtgacctcca tgcggtccag gatgtccacc
    10561 actctctcgt agaactcatc tagtttttcc gtggtcaccg ccccttccgg agagggattt
    10621 atgaggcctt cctgctccaa tatgcgcaat gagtaacgca ccttgtgctg cgggatgtcc
    10681 agcagctcgg acagccggat gatgccgata ggttcgtgct tttttatagc gttcaacatg
    10741 accacgtgcc tttccaggag ctcgacctcg gcctctatct tactggtgag aacgctgtga
    10801 cccttcatga cggcaacttc ctatgagcta gacacgtgat aacattgggt atagttaaat
    10861 ccgtttcgcc taaaaacttc cattaccggt tcctagcgcg caccccttaa atatgccgcg
    10921 aggcatgatt tgccgcatgc cggcgatcgt ggtggatgga ctgaccaaaa ggtacggtga
    10981 gttcgtggcc ctggaccaag cgacgttcac cgtggacgaa ggcgccttct tcggctgctt
    11041 cgggcctaac ggcgcaggaa agtccaccct tctgaagata ctcaccggtc agatcccggc
    11101 caccggcggc accgccgagg tcctcgggct ggaccctgcc aagaacgcca tggaggtgaa
    11161 gagacgcatc ggcatcgtcc cggaggtgga gagcccgcca tcgtacctga ccgcctcgga
    11221 gttcctgagg ttcgcgggaa ccctgcacga ggtgcagtcc ctggacggaa ggatcgagag
    11281 atggctcacc ttcttcgatc tgaaaggggc ggaaggaact ctatgtcgcg acctctccaa
    11341 gggcatgagg cagaaggtga tgctggccgc ggccttcatc cacgagccga aactgctgtt
    11401 cctggacgag cccttcatca atctggaccc catctatcag cgcaagctgc gcgattacct
    11461 cctggacctc cgggaggacg gccggacggt gttcctctgc tcacatatcc tggacgtggc
    11521 gcagcgcatc gtgcaggaga tgatcatcat ggaccgcggc aaggtggtcc tcaaggacaa
    11581 ggtctccaac gccttggtgg gcggggagga cctggaaacg ctgttcctga ggctggtggg
    11641 tggggggaac ggcctcgctc cttaggctga tgctcaccga ggagtaccgt atgcacgtga
    11701 agtactcctc acgccagatg ttcctgtcgt tgccattgta catattcttc ttcacggccc
    11761 tcttcaccta cggcctggat atattgaccg gagatctccg tctctgggac ctgatgctca
    11821 tggcctatgg tggcatctac atctacggtc tcagcgtggg ggcgttcgga gttctgggcc
    11881 agagctatct cgaacggagg tatggcaagg acaacttcct gatcagcatg cccttcctgc
    11941 ttcccgtatc cttccgcaag gtgttcctgg gaatgtactt gcgggacgtg atcttctact
    12001 ccgccctcat gctcctgccc gccttcggcg gaatggcgct cggagcggcg ctttcgtctc
    12061 attccctgat ctcggtcctg gtgatattca ttgggctcct ggtaaccttc ctctacggga
    12121 tgtcgaccag cttcctgatc tcggtgctgt tcgccatcga ccggaggata ttcctgctgg
    12181 ccgtcggagg attgatcgcc ctggtggccg gttacggtct cacgggcctg tatggcctgg
    12241 acctgatcat acccagtctg gggtatcagt tgaaagcgct gcccttcccg gccgattggc
    12301 cgctggcgtt gttctatctg gcgatctgcg ccgcgctcag cgtggccttc ctggccctgt
    12361 cactgatgct ggtccggccc ggaaggtccg tgatggtcgg gacccatcgg gagatgttcc
    12421 tgcagcatct gaaggtcttc tccagattcc catcgagggc gcttctggcc aaggagttcg
    12481 tggacatccg gcgctccggc ctcaccgtcc gcatgatatt cgcctacgtg gtgcctctgg
    12541 tgttcctgag cttcaccact tactacgtga accacggcct gaacatcccg gtgggcttca
    12601 acgccgtgtt ctatggggcg atggtgggtt tctttggcgt tctcctctac agctggatga
    12661 ccaacacgga cctgaacgat tattacgaga cgctgccggt gcgggttccc cagataatca
    12721 aggtcaagct gatggcctac ttcctgctga ccaccggtgt ctccacgctc ttcgtcatcg
    12781 gcatctccat gctcaacgac gaatggcagc tgctgtggct ggccctggtc gtcctttact
    12841 gcaccacggc ctacatgata ctggccacgg cgtatctcac ggggttgaac accaactcct
    12901 tcttcttcaa tcccacggtc ctcaccaagt tcaccgccat atccctcctt cccgacctgc
    12961 tgctgaccat tctttccttc agtctgcaga gcggggcctg gtgggccctc gccgggatcc
    13021 tgggggtgtg cggggtcctt ctgatcctga gcctctattt ctatcgggga atcgaaaaaa
    13081 aatggggcgg cgccagtttt ctatgagaac gcgctcattt gaccaatctc attatgtagg
    13141 gtaaggcaat accaaagtca tggattggca ccgggtgagg cgattgatcc atgttctagc
    13201 gccgctccta tgcatctatt acatcgttcc cgatccagtg gtccccggtg tgccgaatga
    13261 ccaggtcatc cttctgctca tgctcatcgt cctggtgttg gacaccatac gtctcatcgc
    13321 ccggttcaag gtcccgatat tgcattcata cgaggacgac cgaccctccg caccagcctt
    13381 cttcgccgta tccgcggcca tcgcccttct cttcttcccg gtggagataa cccttccagt
    13441 actgctgggc atgggggtgg tcgatcctct ggtcggggaa ctgaggatgc ggaagagcga
    13501 cctgaacccc gtgttgccca tggcggtcta tttcttcata ttgctgatcg gtctgggcta
    13561 cttctatggg ctgagcttcc tggtgctgct gtcctgcctg ctggtggctc ccatcgccct
    13621 gtttctggaa tcccgacgat tgccctacat cgacgatgat atgatactgg tactggtgcc
    13681 actgttcttg ctggcactga tgttcggtca gcttcccttc tgatagacaa aaagaaaagg
    13741 gctcagttgc cgatcaggcc cttgcgcttg ctgaaaccgg tgagcccttg ctcgacggtc
    13801 tgggtaggcc ctttgtggca gttctccgcc ccgtcaaggg tctggtgcac cttgttgcac
    13861 accaagcact ggtagatgat cttgctcatt ggggcttaga aatcgagagg aggcatataa
    13921 tgttattccc ttccccttcg ccccggccaa gaatgggatg gaaaagcata tttcacctca
    13981 tgatcattac gactggcgaa gttcttttgt atagctttct tcgatacaag cgaattatcg
    14041 ggtgaatccg catagttttt attgccaaaa agcaattagt ggaggtatga ataaaattaa
    14101 ggtcatcaac gaaccctccg agttggtatc tatgctgagg gcggtagata ccccggtgaa
    14161 gagggatgtc ctgaaagagg tgaccttgga atggcgcacc gtcaaggaga tcgaggagaa
    14221 gtatggggcc gagggaaaag aggccttggc ctttttcgag aagatgaagc tggtggagac
    14281 cagatggcag ccttcgggag gcaatcgccc ggacaaggcc tatcacactt actacaactc
    14341 cttccatatc aatgcccaat ggccggtcta tgagatctct gatgtgctct acgcggccat
    14401 gatgcccgat gaggagttcg aggagatcga gaacaacatc ttggagcagg tgggcaagga
    14461 aggtcgcttc gccggcgacg tcgccgagaa cctggggatg acggccacca tgctgaagag
    14521 cctggtgaag cgctcgataa agatggacta ccgcggccac cgtctggaaa tggtgaagga
    14581 gtaaggtgcc agagataact gtcctccggc tgggccaccg tccggagagg gacaagagga
    14641 tcaccaccca cgtggccctg accgcccgcg ccttcggggc caggcgcata atagtctcca
    14701 ccaaggaccc ggttctggaa gagagcataa acgacgtggt gaagcgcttc ggcggcgatt
    14761 tcgagatcac caccggcgtc aactggagga ggttcttgca ggacttccag ggaacggtcg
    14821 ttcatctcac catgtacggg cttccggtgg acgaggcggc tcccaacgtt ccggatggta
    14881 acgttctggt ggtcgtgggg gcggagaagg ttccgcccga ggtctaccag agggcggacc
    14941 tgaacgtggc ggtgggcaac cagccccatt ctgaagtggc tgcgctggcc atattactgg
    15001 accgggtgtt ccagggccgc atgctgcaga gggactatca gggggcgcag atcaaggtgc
    15061 taccctgtga gagggggaag aacgttgtcg aactatccaa gcactgacga atgctaccag
    15121 ataatgcgag aggagaagct ttccacggtc gtcgttcgtc attgctgcgt cgtgaacctg
    15181 gtggccctga gcatcgcccg ccgctgcggt gcggatctgg agcttgtcaa tgctgcctca
    15241 ctgctccatg acatcgggcg ttcgagaacc cacggcgtgc agcacgtggc ggagggtgtg
    15301 cgcatagcga aggaacacca gctcccggac gatctggtga actgcatagg tcggcacatc
    15361 gcttccggtt tcacgtccga ggaggccgaa gcgttgggtc ttacgaaggg tgactatatg
    15421 ccggttacac tggaggacaa ggtggtgaac ttcgccgaca atctggtcag cgaccgttcc
    15481 atcaagaccg tggcgcaggc cgtggagcgc atgcgcagca agggattcga gctgaccgcc
    15541 gaccgcatgc tggccatggg tcaggagata tccaagctgt gcggcgagga catcgatacc
    15601 attctgcaaa aggaccaggt cagggaggcc gcggccgccc tctgcgacaa gatggcctga
    15661 tattcctggt tcgggtaata attcacaaag gttttatccg tgtcactact taccaaggcg
    15721 cacgcctacc gaccccgatc ggggcgttaa cgatcactgg agatttggca tgtccgagaa
    15781 gaagatcatg atgtggatga acggcaagtt gatcgaacag gagaaggtgc tgctgccctt
    15841 catgacccac gccctgcact atggcagcgg ggtgttcgag ggcatccgga tctacgagac
    15901 gcctaagggc aaggcggtgt tccgcctccg ggagcacatg gtgcgcttcc tggactcggc
    15961 caaggtcatg tgcatgaccc acccctatac ggtggacgag ctggtggagg ccacccggct
    16021 tgcggtccgc aacgcggccg ataacgccga ctacatccgc cctctcatgt ggtacgggga
    16081 gaacgacgag aaccgcatcg tactgaaccc gttcaagttc aaggtcaaca cggcaatcgc
    16141 ctgcgctcac atgggggcct atctcggcaa ggacaacatg gagaacggcg ccaaggtcat
    16201 aacctcatct tggaccaagc cggccaacac ctccacgtcc ttgcaggcca agatatgcgg
    16261 caactacgtc aactccatac tggcgaagat agagtccaac cagctagggg cggacgagtg
    16321 cctgatgctc aacaccaacg ggacggtggc cgagggcccg ggcgagaaca tcttcatgat
    16381 caagaacggc aaggtataca cccccccgct ggcgtcagga gtgttggaag gcataaccaa
    16441 ggactccgtt tccaccatag ccaaggacaa gggctaccag gtcatcgaga aggagatcac
    16501 ccgctccgag atctacatgt gcgatgagtt cttcatgacc ggcacggccg cggaggtcac
    16561 tccgatccgt tcgctggacc agagggtcat cggcacgggc aagcgcgggc cgatcaccaa
    16621 ggacctgcag gaggccttct tcgaggccgc ccgcggcaag gacccgaagt acagccactg
    16681 gctgacaccg gtcaactgat ccggaaaacc tcttccacaa ccttcttatc atatctgctg
    16741 gcgaaaccag tctctcaggg atgaaacatg tacgagatca ggttccacgg acgagggggt
    16801 caaggggcgg tcatggccgc ccagaccata gcggaggcgg cgatcctgga ggggaagcag
    16861 gctcaagcgt tcccgttctt cggcgcggag cgccggggcg ctccggtgat ggccttcgcc
    16921 cgcattgacg acaagcgcat ctgcgaccgt acccaggtgt ccgagccgga cctgctggtg
    16981 gtcatggacg aatcgctgct ggagatagag ccggtggcct ccggcctcaa gaaaggagga
    17041 tgcgcggtgg tgaacagcgc cctcccgcca tccgagatag atctgggcgt ggtaacgcgt
    17101 tgcgtgagcg tggatgccac cagcatcgcc ctggagatgc tcaaggcacc catcgtaaac
    17161 acgtcgatcc tgggggccat ggcccgcgcc gatgatttcg tgaagctgga atcgatacag
    17221 caggctatca tgaaccgctt cggggagaaa ctgggcgaga aggctgggcg tttgaacgcc
    17281 gaggcggccc aggccgctta cgagcgctct ctcgaaggca cgtgcaaggg ggagcgcaag
    17341 gtccagagga agaacgcttg gctgccgacc tggcaggaga ctcctcccgg cgtggcgctg
    17401 ccaaagacca ccaaggccgg catggccgtc ggtcctggaa gcatggccca gaacctcacc
    17461 gggagctggg gagtctccaa tcccgtttac gatgaaacca aatgcatcag gtgccagagg
    17521 tgctggttca tctgtcccga ggggtgcata cgccgttccg atgacggagc gctgcagttc
    17581 gacatccgct actgcaaggg ctgcgggctg tgcgtcaagg tctgcccgaa ggatgccata
    17641 cacatgaaga gaaaggggat gaaagcatga ggtcggtcag agctttaacg ggaaacgcgg
    17701 cggcggcgta cggcgtgaaa ctatgccggc cggaggtcat tcccaattat ccgataacgc
    17761 cgcagaccat catcatcgag cagctcgccg acttcatcaa cgacggggag ctggacgctg
    17821 atttcattcc cgcagacagc gagcactcgg ccatgagcat ggccatcggc gcggcggcca
    17881 ccggcgtgag gacgttcacc gccaccgcct cgcatggcct ggcgctaatg catgagatgc
    17941 tctacgtgcc gccgcaggtg cgcctgccga tactattggt gaacgtgaac cgttcgctgg
    18001 gcgccggcag cggcatctgg gtggagtaca acgactccat ggccgagcgc gactcggggt
    18061 ggatgcaggc ttacgcggag gacagccagg aggtcctgga catggtcata caggcctacc
    18121 gcatcgccga ggatccgcga gtggtgctcc cgttcatgct ctgcctggac ggattcattt
    18181 tgtcgcacac ggtggagagg gtggaggtcc cgggacagga ggaggtggat tccttcctgc
    18241 ccaagttcaa accgctgaac cgtctggacc ccaaggatcc gatgagcatc aacatcgccg
    18301 tttctccggc gcactccatg gagatgcgct atcagctcga taggcagatg gaaggcgcac
    18361 gcaaggtgat atccgaagtg gacgatcttt tcgccaaggg gttcggaagg agatacggcg
    18421 gactcataga cacctaccgc atggaggacg cggagacggc gctcatcacg ctcggcacgg
    18481 caacctccac cgcccgagtg gctgtggacg agctgcgtgc cgaaggccgg aaggtcgggc
    18541 tgatcaagct gcgcttcatg cggcccttcc cgcacgacga gatcaagaac gccgtcagga
    18601 acatcaaggc cctgggcgta ttcgaccgtt ccatctctgc gaaccggttc ggcccggtat
    18661 tcaccgaggt ccgcaattcg ttgtacgtta gcggaattcc gataaccgat catatcgccg
    18721 gcatcggcgg ccgcgacctg aaggtcgcca ccttcaagga gatgttcgag gtgctggaga
    18781 agagcgcttc cggccagaag gtaagggact gcacctggca cggcctgcgg ggggagatgt
    18841 gatggaccgc aagatgaaca tccggaacat gccgagcgag gaccatctgc tctgcggaca
    18901 gggcgcttgc gccggctgcg gcgtggccat agcggtcaag aacatcatga ggatacttgg
    18961 cgagaacacc acggtctacg ttccagcaag ctgcctgctg gtcttcggcg gcggcatgta
    19021 tccgcactcc gccttcgacg ttccgttctt ctacagcgcc ttcgaaaaca ccggggcggt
    19081 gatatccggc ataaaggcgg gataccgccg gcagggtaag gatgtgacgg tcatcggtat
    19141 cgctggcgac ggcggtacct tcgacatagg gctccaagct ctggccgggg ccgcggaacg
    19201 caatgaggac gtcatctacg tctgcgtcga caacgaggcc tacatgaaca ccgggacgca
    19261 acgttccggc tccacgccct tcggggcctg gaccaccacc acgccggtgg gcaagaagat
    19321 caagggcaag cagggcttca agaaggacct gatgtccgtg gtcacctcgc aggacatagc
    19381 gtacgcggcc acattgtcga tagcgcacat gaacgacttc gtgcagaagg tggagaaggc
    19441 caagaacctc aaaggcttcc gtttcctaca tgtgatgacg ccctgcacct ccggctggaa
    19501 gagcgacccc tcggcgacgt tcgacctggc caacatggcc gtggagaccg ggatgtggtc
    19561 cctgtacgag gtgatggacg gcgaggtgaa catcacctat cgtcccaagg aaatgaggcc
    19621 ggtgacggag tacctgaagc tacagggccg tttcaagcac atgagcaagg aggacgtgga
    19681 caccttgcag acctggatat gcaagaaatg gaacaagcgc tattgcccga tcgcgcctcc
    19741 catggacggt aaggaagagg acctggcgta cgacggcgac gagtgcgagg gcgtctgatc
    19801 gttcagcgtt tgtccaacag cactccgatg atcagggcga tcaccgaggc cgggagggcg
    19861 atgaccagag ggtccaccac cgtccacgga ctggccaata ccgcatccgt tccgaacaat
    19921 gccttcgata tcccgagcac cgacgattcc ttgatgtgca cgaaggcggt ccacaggaac
    19981 caggttccgg ttcctaccgc caggctcagt ttggccgcta gtaccgacgg cctctccgag
    20041 aatatcgcca atgtgaacag cggcaggaac gccgccgcgc tcaagcccat gaacatagcc
    20101 gtcgcccggg ctattatact tccaggcatc aagaacgcca ggccgatgct gaccgctatc
    20161 ataatcgtcg taccggtgcg gttggcccgg agggaggagc agtccccggt cctctcctta
    20221 cgtatgctcg agggcatcag gcggcagctt ccaagatgcg tccagagatc atgcccggcc
    20281 gccgagccca tggaatggaa cagggcgctc agggtggaca tggccgccgc cagcaaggtg
    20341 agcatgaaca gtatcaccac cacgtccggc atggccgtgt tgatgaagag cgggatgatc
    20401 tggtctatgt tgccgctcac catggatgtg gatatgaccc cgttctcccg gtaaaaataa
    20461 acgttcgtca atgcgccgac ggtgaaggcc acacccgtgc acagcaggat gaacaaaccg
    20521 cccaccggga tggccctgtt cagcgagcga tcgtccttgg cggtcatgta gcggacgacg
    20581 agctgcggtt gtgccagtac tccgattccc acacccatga cgatggtggt gatcagagtg
    20641 aaccagatcg gcgaaccgag ttcgggcatg gaggtccaac cggtcattcc ttgaccggcc
    20701 agtccagccg ggaccaggga ggccatgtcc gtgagctcct ggtgagctcc ggtaactccg
    20761 cccaatgtca cgtaggtaat gatcaggatg gccaccatcc cgaataccat tatgccgccc
    20821 tggaaggcgt cggtgtacat caccgccagt attccaccga aaaccacgta tagggcggtg
    20881 atcagggcga accccaggag cgccgtcgta tagtcgattc ccaaggtggt ctcaatgaat
    20941 cgcgaaccgc cgataagaac ggccgaggaa taaagaggca tggaagccaa gattatgacg
    21001 ctcgtcccgt actggaggaa attggaattg taacgcttgg ccaggaggtc cggcagcgtc
    21061 accgccccca ggcgttggcc gatgcgcctg gttctctttc cgtagacgat gaaggctatg
    21121 agaacgccga cgccgatgca cagcaccgtc agccagatta ttcccattcc cagttgcgca
    21181 gccaccccgc cgaagcccac gatggccgag gtgctgatga acgtcgaacc gtaggagagc
    21241 ccgattatgg ccgggtggac ctttcgtccg gcgagaagat agtcctctcc cttcttcgtg
    21301 cgccggtagg cgatgaagga gatggcgaga aggattccca cgtagagcgc ggtgaaagcg
    21361 gccagggtga gaacgtcaac caccgttctc ccctccgtcg ttccaatgca ggatcccata
    21421 tgccaggcac attaacccca gtcctatggc cagggcgtag cccacaatga tctgcggatc
    21481 gtcgataccc aacatacccc ttcccccgtt ccggtcttcc ctcatcatcg gaccgcccgg
    21541 atggaaggcc cgttggcagg ccatataaat tttattttat atatatgtta caagttagta
    21601 cgctacacgg tagcacgaat tatttttaaa aaatgaaaag aaaatggttt acgcctcagc
    21661 aggcgctgaa gaccgtctcc tttcgatcat ggtcccgatg atcagggcgg ctatcgacag
    21721 cggtagggcg atgaacaggg agtccaccac cgtccagggg aagtccagga ccgacgggct
    21781 cccggtcagt atctccgaca atctgagcac gctagactcg gccttgtgca cgaacaccgt
    21841 ccacacggcc cagacaatgc ttccggtcag gaggctggct attgccccta gacgcgaagg
    21901 gttcttgacg aacacggcga cggtataggc gggcaggaac gccgcggcgc atagtcccat
    21961 gaacatggcg gtggctcgag cgatgatgtc cccgggcatt atgaaggcca gtcccaaact
    22021 ggcggcgatc atgacgaagg tgccgatctt gttcaccctg agcttggagg cgtcctcgtc
    22081 gctgccgcgc atccgggacg ggaagaacct ggccctgcgg acgtgcaccc agatgtcgtg
    22141 cccggccgcc gtgcccatga catggaacaa cgagctcatg gtggacatgg ccgcggccaa
    22201 aagcaccagt acgaacatca cgaccagcca ttccggcatc gccgtatcga tgaacagcgg
    22261 tacgatgttg tcgatgttcc cggtcatctg cgtggagatc tttccgaagt tattgtagaa
    22321 gtagacgttg gtcagcgcgc ccatggtgta cgcaacgccg gtcgttatga gtatgaatat
    22381 cgctcccaca ggtatggcgc ggttcaggga cttgccgtcc ttggcggtca tgaagcgaac
    22441 cgccagctgt ggctgggcca gcactcctat ccctactccc atgatcacgg tcgtcaccag
    22501 cgtataccag gtcgccgaac cgagctccgg gaaggaggtc cagccggtca tgccggtgct
    22561 ggccagtccg gccgggacca ggtgggacat gtcggtgagg ctttggaagc cgtcgaatcc
    22621 cccgacggcc gacagggtga atatcatgat ggcgctcatt ccgaagatca tcagcgatcc
    22681 ttgcagggcg tcggtgtaca tgaccgccac cagacctccg aacacgacat aggcggcggt
    22741 gatcgccgtc agcccaatta tggcccagag atacggaacg tccagcacct cttcgatgaa
    22801 gcgtcctccg ccgatgagca cggcggacga atacaacggc atccccacga ttatgatgag
    22861 gccggtaacg tactgcatga agttcgattt gtacaccttg cccagaaggt ccgggaaggt
    22921 cagcgcgcct aacctcttgc cgatccgtct cgttggctta ccgaagacga tgaaagctat
    22981 cagcacgccc accgatatgt tcagcatcac cagccaaatg atccccatgc ctagcttggc
    23041 ggcgtaaccg ccgaatccca ctatggccga ggtgctgatg aacgtcgcac cgtacgatag
    23101 gcccaggatc accggatgaa cgttccttcc ggccagcatg tagtcggcgt tggacctggt
    23161 cttcttataa ccaagccagg cgagatagaa tatcaccacg gcatagaccg cggtggccgc
    23221 ccagaaatag agttggttga ccatctcagt cgacctcctc gttccatttc attattccgt
    23281 agatcacgcc gatcgcagtg cttatgaagc agagcgcata ccccagcaat atccaggggt
    23341 catctatgcc gaacatcttg tagcctctct ccctcgagcc agaagtattt gagggagatt
    23401 tgctggatgt tatttaaatg ttacatgtta gcatgttaca cattagcata ttcagaagac
    23461 gcgcctatcc acgaccctct tggccttgcc ttcgaaacgg ggcagcgagc caggctccac
    23521 gatctccacg ctcaccccga cgttcagagc gtcgcgcagc ttgtgcgtga gccggtcctt
    23581 aatggcatcc agctcgaaca cccgatcgcc gaaggcctcc gggcgcagct ccaccttgac
    23641 cagtaggctg tctagagcgc ctttacggtc cacgactatc tggaactcgt tgccgacctc
    23701 cgggtgctgc atgagcgagt actccacctg tgacgggaag acgttgatgc cccggatgat
    23761 gatcatgtcg tccacccttc cctggatcct gccgatgcgg ggatgcgtcc tcccgcaagc
    23821 gcagacctcc tcgctgaccg tggtgatatc gccagtacga tagcggacga tgggcaacgc
    23881 ctccttcagg agcatggtca ccaccagctc gcccttcccc cccggaggca caggctcatc
    23941 ggtctcgggg tccagcacct cgaccagcgt gatgtccccc cagacgtgaa tgccgttctg
    24001 ctccgagcac tcgcaccaaa gcgggccgga aagctcgctc gttccataga tatcgatggc
    24061 cttgatgccc aggcgttcga agatgcggtc ccgcatccgc tcgctccacg gttccgctcc
    24121 caggatgccc aggcgcagct tggtgtcctt tcgaatgtcc acgcccatct tagccgccac
    24181 ctcgcccatg tgcagcaggt acgacggcgt tgcggcaatg accgtcacgt cgaggtctcg
    24241 caccaggtcg atctggcgct cggtgttccc ggtggatgcc ggaacgaccg ccgctccgac
    24301 cttctccgcg ccgtagtgca accccaggcc gccggagaag agaccgtagg tgtagcagac
    24361 ctgcagaacg tcgtccgtgc ccacgccggc cgagacgagc ccccgggcca ccgattccga
    24421 ccagttctcg atgtcgttct gggtgtagcc gacgatggtc ggcttaccag tggtcccgga
    24481 cgaggcgtga tatctcacca cctctctggg gctggccagg aacagcttgt ccggatatcc
    24541 gtcccgcagg tccttcttgg tcatgaacgg gagcttccga acgtcatcca gctcctggat
    24601 gtcctccggg gttacccccg cctccttcat cttctgtcga tagaacggag agaaggtgta
    24661 cagcttgtat accagcatct tcagctgctt gagctgcaag gccttcagct ccgggaccgg
    24721 catgacctct acagggttcc agtatgacat atgttgcacc tcagccagtt gccgcttcca
    24781 tcagtggaac gtaacgttgt ccaggagtct taggcctccg gccaacagag aactgatgcc
    24841 ctgttcgatt tcctccacgc ggacgatcag tacggcgtat ggagggttgc ggtaaccgta
    24901 tccgtactcg atgttgatgt ccttcatctg gtccgtcagg tcgaacaatc cgccgggagt
    24961 gtcctgcatc tggatggcca gaacctcggt gaacttgacc acgaagccgt ccttgatcag
    25021 gaggtccctg gcgatatctg gtctgtcaac cagcacgcgg atgacaccgt aaccggcgcc
    25081 ctcggcgatg ctgaagccca ggatgttgat cttgccttcc ttgagcacct tggccaccgc
    25141 gcccaggcgg ttcggtcggt tctccgagaa gatggagagc tgcttaatcc ggtacttgtc
    25201 gttctcgctc atcagtattc cctcctgtcc accacccgct tggccttgcc ctcgaaacgg
    25261 ggcagggtgc caggctgcac cagctccacg ttggccgaga cgttcagaac gttcttcagc
    25321 cggttggaga tgcgctcgcg cagggcgttc agctcgatga tgttgtccgt gaatgcctca
    25381 ggttttagct cggcccgaac cagcatggtg tccaggtggc ccttgcggtc caccaccagc
    25441 tggaactcgt tgccgacctc cgaatgctgc atcaacgagt gctccacctg cgaggggaac
    25501 acattgatgc cgcgaataat aatcatatcg tccacgcgcc cctggatgcg
//
LOCUS       DAOPZI010000022        24401 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_2053_length_24401_cov_9.713957, whole genome shotgun sequence.
ACCESSION   DAOPZI010000022 DAOPZI010000000
VERSION     DAOPZI010000022.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 24401)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 24401)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24401
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2053_length_24401_cov_9.713957"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..911)
                     /locus_tag="PKM11_05500"
     CDS             complement(<1..911)
                     /locus_tag="PKM11_05500"
                     /inference="COORDINATES: protein motif:HMM:NF014567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HNX47993.1"
                     /translation="MSDDRDLDRSRPQFLELLRTLQGCEDRESAMRAAMDMVAGVFQP
                     VSICYLPEGGGRPLGDCGPWTSGAHLPPNQIVKLLPSKKGFALAIKERGKRVGVLCAD
                     QVEQPRSLDVNLPMLMSIPDALEIAFSNIRLLQELRDSQDRLARLSESLGVANKILRH
                     DIANELLVISSSLDLYKQNNRERDLLRAQTSLLRMQSIIAQMRELDRFLFSQAELVGM
                     ELREVIDKVMAGLDTPYSVEGDGKVLADPALTAIIENLARNAKRHGKAEKVEFTVASS
                     GGRPVLVVRDDGIGIKEEYLPRVFMEGV"
     gene            complement(1010..1276)
                     /locus_tag="PKM11_05505"
     CDS             complement(1010..1276)
                     /locus_tag="PKM11_05505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX47994.1"
                     /translation="MSSLLVRLLRPRHPRVGEAVIPDPEMLDYYFEEYQLGSVIRTLI
                     RSDPPINGVSQRLPLGTEGPKKQDGLVGPMDVWLVHDLLNEMMK"
     gene            complement(1346..2446)
                     /locus_tag="PKM11_05510"
     CDS             complement(1346..2446)
                     /locus_tag="PKM11_05510"
                     /inference="COORDINATES: protein motif:HMM:NF019887.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HNX47995.1"
                     /translation="MMDEAFPFEGKILVSDLQGPVTANDNARELTTAIVENGDRLFQA
                     IRRYEGALSNVSRKEGVKPGDSLRLILPFLKAYGATDSSLLRFSKDSIRIVPGADKAM
                     RYVQELMSSFIVSTSYEHYVGAVCDRIGFPFENTFCTRLSMDMLDLEDWETETLRNLV
                     QEIVRLPLLEVPEGASSIRDLSSDDRLVLRRLDEIFWTEMTDLSSYQLISQVNPVGGD
                     EKATSVVEICKRMSVPLEDCMYIGDGQTDARVLQVVRRSGGLSIALNGDLSALREAEV
                     GVVSENAIVTSILAELFYRGGRDGVLEALEDWSLDGLRGNGVVHEYLLREFARTFPEG
                     FPTVRQLDKESLPGMAKASLAMRERVRGLSLP"
     gene            complement(2526..2930)
                     /locus_tag="PKM11_05515"
     CDS             complement(2526..2930)
                     /locus_tag="PKM11_05515"
                     /inference="COORDINATES: protein motif:HMM:NF001617.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="archease"
                     /protein_id="HNX47996.1"
                     /translation="MKYRTLDHTADVMVEAFGESLEECFANAAYALMDQMVDASKVRE
                     REERLMVTEGHDHESMLYNFLSEFLYVFDVTGMVFSRFSVTFFGNEVHCKAWGEKYDA
                     QRHQPKKEIKAITYHMMSVDPVRPSVRVVFDI"
     gene            3040..3858
                     /locus_tag="PKM11_05520"
     CDS             3040..3858
                     /locus_tag="PKM11_05520"
                     /EC_number="1.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate dehydrogenase"
                     /protein_id="HNX47997.1"
                     /translation="MRLLIIGSGAIGTTLAEAIQDMDEFDIFYITDKNEERAKTIAAR
                     CKKAKFISPTDESIKAHLKNVDLVVEAASQEAVQHYVPIVLGMGVDVLVMSVGAFADD
                     DTRERCFNVAKRKGGRLFVPSGAICGTDGLHSASADVIDSVELTSTKGPKSFHDNEYL
                     LSKGVDVNTLKKKTVIFEGPAREAVQHFPKNVNVSATISLIGIGLDKTKVKLVCDPVS
                     DCNTHRLEVRGEFGHIVCETDNLPFPSNPATSYLAALSAIAAIRRIAGNVWIGI"
     gene            3905..4996
                     /locus_tag="PKM11_05525"
     CDS             3905..4996
                     /locus_tag="PKM11_05525"
                     /inference="COORDINATES: protein motif:HMM:NF012766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HNX47998.1"
                     /translation="MKERVKWIFSNCPSDLDAIVIMNGEEPLLDVAFPYVTGTRAGLF
                     EGCLGVITPDGRSHIITSALEETSARDGKAEVLTYRTSQERKDIATDLMKAFRKVGVN
                     GQGIVHSNYLEVQRLAAKAELIDISKGLETSRLIKDQEELRRMRKACSIASRVADEIP
                     SFLRKGMKEYEAAAELDYRMTRMGASGAAFGTNASFGPSSAEPHHGAEDIALKEGDTT
                     LFDFGCKVEGYCSDITRTFFFGEPKDWQKRMYQVVTEAQQAALSVIRAGANGKDVDSA
                     ARTVIDASEFKGLMVHSTGHGLGLSVHDGGRMAPNHDFPLKAGMVLTVEPGVYIRGQG
                     GVRIEDDVLITEDGYEMLTDADKKMKVIQ"
     gene            4993..6369
                     /locus_tag="PKM11_05530"
     CDS             4993..6369
                     /locus_tag="PKM11_05530"
                     /inference="COORDINATES: protein motif:HMM:NF039907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HNX47999.1"
                     /translation="MMDELQLAVERMRAEGADFCDARYQTITTNGIAVVDAAVRRISE
                     DRIRGVCLRAKKKGSWGYATTVDSSKDVVLEAAVMAARNALAGNAVGKIIPDTGDMKV
                     ELKANVKFHPSQVPMEEKVQAVLDMDRAQKVDPRIVNTNSILREELRQNMLVNSHGRQ
                     LSWEEVRTTIMVQAVASEAGRTEFFYDIRGGGLGYEVVKDTDLESFGREVGKESLKML
                     TAEKAPSGLLTCITDPSISGLLAHEVMGHASEADEIVKRRSFLTDKVGKRVASPLITM
                     VDDGTVPEARGSIPFDDEGTPSSRTMIIKDGVYQGYMQSLETAAEMGVRPTGNGRAQS
                     YDRRVWVRMTNTFFDKGDQNLDEMIADVKYGVLTDRMISGMEDPVGGGFEAKALRGFL
                     IENGRITKLLRSFTLTGNALEILGTGDAVGNKVELDGGSCGKGIEDWVPVSSGGPHCR
                     FKIVLGGD"
     gene            6370..>6774
                     /locus_tag="PKM11_05535"
     CDS             6370..>6774
                     /locus_tag="PKM11_05535"
                     /inference="COORDINATES: protein motif:HMM:NF013673.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase modulator"
                     /protein_id="HNX48000.1"
                     /translation="MDLERISKKSVSKVLEEGAKEVESYLVRVRSLTAYIDDDRVKNL
                     EEKLDQGISIRVLLNGKLGQSSSTFNTTRDLEECGAKAVALAKLSRPDPYFKRFPGFS
                     QPVGHVDVRQEDVATATTGYLKQKVEEIVKAAG"
     assembly_gap    6775..6874
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6875..7455
                     /locus_tag="PKM11_05540"
     CDS             <6875..7455
                     /locus_tag="PKM11_05540"
                     /inference="COORDINATES: protein motif:HMM:NF039907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metallopeptidase TldD-related protein"
                     /protein_id="HNX48001.1"
                     /translation="DLVNKEVGNELVNLRDQPYDPRSSLSCRYDDEGTVTREKPLVER
                     GTLRTLLYDSYHAQMGKVAATGNYLRRDPSDALNLYRRGGVTLPVNLAWKPGTQSVED
                     MISDVKEGIIIEKLAAPDVNSVTGGFALEVRCAKLVRDGSVVGHVDQCLLVGNFYQAL
                     KRVGAVGNDVAVHRNCIIPSVRFDGLEIVGSD"
     gene            complement(7456..7827)
                     /locus_tag="PKM11_05545"
     CDS             complement(7456..7827)
                     /locus_tag="PKM11_05545"
                     /inference="COORDINATES: protein motif:HMM:NF016050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclophilin-like fold protein"
                     /protein_id="HNX48002.1"
                     /translation="MDRILLRTRYERWEIELNDSLAAFKLYGTLPLEREINVWGGELF
                     FPVPVECPLENGRKIMEVGEVAFWPEGNAFCIFFGKTPASTTSKPEAYSKVTPIGRVL
                     GDVSTMSDLADRTRVTLEPMV"
     gene            complement(7875..8864)
                     /gene="ilvC"
                     /locus_tag="PKM11_05550"
     CDS             complement(7875..8864)
                     /gene="ilvC"
                     /locus_tag="PKM11_05550"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HNX48003.1"
                     /translation="MARIYHESDADLNVLKGKKVAVIGFGSQGKAQALCLHDSGLDVT
                     VGVRKDGKSWVDAKKNGLKVDTVAGAVKGADVVMVLIPDEVQGDVYAAEIEPNLKSGA
                     ALEFAHGFAITFGTIKPPKTVDVIMMAPKAPGPMERKVFLEGFGVPALIAVHQDHSGK
                     AKSIALALAKGLGSTKAGVLETDFREEATSDLFGEQAVLCGGVTALINAGFQTLVKRG
                     YQPEIAYFECLHEVKLIVDLIYSGGMMNMWRSVSNTAEFGGLTTRDLVINEESKAAME
                     KMLDRICSGEFAKEWLDDAHKGMPRMKALEKAEGDSQVEKVGTEIRALFESKK"
     gene            complement(8931..10610)
                     /gene="ilvB"
                     /locus_tag="PKM11_05555"
     CDS             complement(8931..10610)
                     /gene="ilvB"
                     /locus_tag="PKM11_05555"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005948 - acetolactate synthase complex
                     [Evidence IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HNX48004.1"
                     /translation="MKGAKAVLELLEGQGVDVMFGYPGGVTIPLYDELLDSSIHHVLV
                     RHEQCAAHMADGYSRTTSKTGVCLATSGPGATNLVTGVATAYADSSPMMVLTGQVATA
                     AIGNNAFQEADIFSLMMPITKHNYRVLKPNDLPEAIKRGMGIANSGRKGPVHIDLPVD
                     VLRGEIDPARLQENFPVPAPYEDFSAVLDAVKMLRDAERPVLMVGGGARWANASSEVL
                     RLAEMLLAPVVTTIMAKAIIPEDHPMSFGMLGMHGRECSRRALLEADVIFAIGARFSD
                     RTIGYDNEVPKDTKVIHLDIDPMEAGKNARTKVRLVGDAKRGLQMVIKALGRSNKAET
                     AWSRRVKELYDGCVCNIDIDEDPVKPQKAIWELRKALSSDAFVVTEVGQNQMWAAHFM
                     RLKSPNQFVTSGGMGTMGFGFPASIGIKYAHRDKQVVDIAGDGSFQMVFQELATAMSE
                     DLPVVVCLLNNGWLGMVKQWQKLMWNRRYCGTELRNNPDFVKLAEAFGAGGMTITRSS
                     ELAEGFKAAFASDVPFVLDIRTDPEEDMLPMVPGGVNSLDGTIRNRCRWNQ"
     gene            10817..11356
                     /locus_tag="PKM11_05560"
     CDS             10817..11356
                     /locus_tag="PKM11_05560"
                     /inference="COORDINATES: protein motif:HMM:NF016144.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HNX48005.1"
                     /translation="MVSIKLPDDERDIVELRDHDPVWKDLFQLERASLLKSLGPLAMT
                     VEHVGSTAVPNLRAKPIIDILVTVNEIRLDALEDSLGRLGYVHVPIGDPERLFFRKGM
                     PRTHHVHVVRHGGNEHRKHLIFRDRLIAHPEELAEYERLKESLALRFREDRQAYSDGK
                     DGFIVMILDRAKDERRSKT"
     gene            11443..>12615
                     /locus_tag="PKM11_05565"
     CDS             11443..>12615
                     /locus_tag="PKM11_05565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48006.1"
                     /translation="MMENGSRSKLLEDPFVKKVWDLIMGESLFKKSSAELASLRESLR
                     RESLQFFTRHSPYYVDLFERLDIDPAKATMHDIAKLAIPSDMLRGEGQKRFLIQDVEE
                     GGETFSSSGTTGKDPVRVYRSPVDLAIMLKANTDLFEHVYGDVLKEGEGVALFMAAPE
                     LRYKLSFVAFVDLTLDKKGIELLYGMDLEDKSQAGTPWQKLTTNKENLLKFLKSKKEP
                     KLFFTAPAGVHILGQKFETMGVGKKIAYKLASGAPPIKLGKGGIIVTGGGSKGFADLP
                     EYPQLVSNAQKHFVSKDADGKQIDTPFMDVLGMTETLTALIDRYGVTDKVPHPLAEAF
                     LLDPLTFEPIEEEGKEGILGIFNPFTTSWLEVFYPGDIMTYHSSKGFYGKEFVYKRR"
     assembly_gap    12616..12715
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <12716..14029
                     /locus_tag="PKM11_05570"
     CDS             <12716..14029
                     /locus_tag="PKM11_05570"
                     /inference="COORDINATES: protein motif:HMM:NF017686.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003995 - acyl-CoA dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0008218 - bioluminescence [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HNX48007.1"
                     /translation="IDERLQVIEHIARKWKQKLDNGDLEELKRDMSASTGYSPALMET
                     ELSFVPAVLGAANIRRNLDASVQGGADALYKFVEVDETEMFRHVPVGPVLIISSGNSI
                     VPTLIPTVVSLVTGNLTILKPSIANYRGVCEVFKLLAEVPDSRAARAVRSALVVSYFG
                     HDSPSLKLALEELPLGMVNFWGAEPARTIVANMVGKNRHHPRFFVNGPFTGMAIIEEG
                     VEPLQAADDLALDVVLYDQQLCSSPTTGVFIGSYDRAKEFLRAAGERLDEAGNEFPLP
                     PDQDRLFVLQGARRYIQTDGGMVLSSKNPENPWTLVLSKGRSSLAGLAAQFPAFNLFA
                     RKRFLEIVVVPDAESAVQLLRSLPDHPAFKGIDGVQSVGLAVTEGSRDPMVNMLIGAG
                     VHRILPLGDMFMRGAVEPYDGVTMSSLFTRIVYWRKANVALEGQL"
     gene            14026..15003
                     /locus_tag="PKM11_05575"
     CDS             14026..15003
                     /locus_tag="PKM11_05575"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HNX48008.1"
                     /translation="MRVLVTGATGFLGGHLIEEMSKGPHVPVCAHRQGSDTKRIDELG
                     LEKVVFDLTDRDSMLQALRNVDAVVHLAAYYTFTGKKEMYEKVNVKGTDDLLKACQET
                     GVKRFLYCSSTEAMGPIESPPGDEDSPLNPQYEYGRSKARAEELVRTSDLDWTILRPS
                     GIYGPSNVDDVAYFFITSFKGFASKFIIGSGKNFIQFVHVKDVVQGFVKALDRPASIR
                     GTYIITQARPYTYEEVYRVLANIFQQKEPRWRVPRSLAKLMMLPIEGFSLLFGRENFL
                     YRRETVNSVTSDRAYKIDRARRDLGYEPIYDLPEGMAETVAWYRENGYL"
     gene            15049..16002
                     /locus_tag="PKM11_05580"
     CDS             15049..16002
                     /locus_tag="PKM11_05580"
                     /inference="COORDINATES: protein motif:HMM:NF013226.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HNX48009.1"
                     /translation="MEKTLYRTLLNMLRISYTLPFVMASVTGAAFALTVCNEWSLAIL
                     IPLDIFFFALFANLSNDYFDHKSGTDATRFDFMTEESKEAIKELYDERIYWDGNIFDK
                     GDVSERTGKIVLAVILAMALLTALPIILHGGWLVVVLGAIGLFLAYFYTAPPLNLGAR
                     GLGELDVGTSFFMMSFFTYYVIRPEWNWQMFLIALIVGTSVLLMRFVDQMSGYQAHLK
                     GGEKDWTVRLGLERAVVAVGIILLFVHVMHLALVYFHPVFLILLLTVPMGRKLMKGLH
                     DKDDALRFIRPAPQIVKMVIFSELLMVISLIVQNALPWTIW"
     gene            complement(15956..16882)
                     /locus_tag="PKM11_05585"
     CDS             complement(15956..16882)
                     /locus_tag="PKM11_05585"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX48010.1"
                     /translation="MGVARTVGQTAYYGIWFLKELLGFKKPLATTMIITYQCNLRCQH
                     CQIAENLPSMPQPHKMPYQVAVEEMQASYDRGARVLFFEGGEPTSWSDGERTLLDLIK
                     AGKDAGFFVIGYTTNGTNVFYLESDVISVSLDGPREVHDAIRCEGVFDKLMENLSKVD
                     HPNVFANMVVMPENKHLIRETAQVVKDNPRINGLMINFLTPPPGSKLLSLDEKRKVVE
                     EIFTLKKEGYPILNSKKGLKELLIEDYSGRCPFWASEFIMPDRSKLYGCPMKGESCKQ
                     CGFNAVREYSLITRGSVTTILSMAGRFGLSTK"
     gene            17094..17357
                     /locus_tag="PKM11_05590"
     CDS             17094..17357
                     /locus_tag="PKM11_05590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5654 family protein"
                     /protein_id="HNX48011.1"
                     /translation="MASLKLEIMDKIVALMTAAFGFVAALAWNGAISQLMTDWLGESG
                     DATLGLIIYAVIVTIVAVIAIVLISRVYGKIKSKEEAKEAAKK"
     gene            17479..>17867
                     /locus_tag="PKM11_05595"
     CDS             17479..>17867
                     /locus_tag="PKM11_05595"
                     /EC_number="1.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HNX48012.1"
                     /translation="MKVKVGINGYGTIGKRVAWAVNRQDDMEIVGVTKTRPSYEASTA
                     IREGCPLYAAHAEDVDNFERAGIQVQGTLEDLLKKVDIIVDCTPGGIGAKNKELYDKA
                     GVRSIFQGGEDHAMAGISFNALANYHEA"
     assembly_gap    17868..17967
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            18238..19470
                     /gene="pgk"
                     /locus_tag="PKM11_05600"
     CDS             18238..19470
                     /gene="pgk"
                     /locus_tag="PKM11_05600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HNX48013.1"
                     /translation="MKDHFTIDDLDIKGKTVIYRVDINCPLKKDTLELANDNRIQEIL
                     PTLRELLKRRAKVVIVAHQSRPGEWDYISLERHAKRTSELLGVEVVYVDDLYGEKAKK
                     VIQRMMPGEAVMLKNVRDEKGEMDKASMEEHSQAPLVKELSALADLYVSDAFGAAHRS
                     QCSLVGFQAVLPSAAGRLMEKELTALGRVIDSPSHPCVFVLGGSKFTDAIKVVDRVLR
                     ENIADKVLMVGLAGNAFLKAKGVSLGEKSEHILMEEFTAENLNAAKGLLDRYGDRIET
                     PVDVALDDGGMRKDVPIGALPSELPICDIGKETAARFSEIVSKACTVFISGPAGVIER
                     EEFSYGTKALMEATVSSDAFSVIGGGHTVSAAQRYHCCDRFSYVSTGGGALENYIMGK
                     PLPVVEALKAAYRREKGK"
     assembly_gap    19589..19688
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<19689..20077)
                     /locus_tag="PKM11_05605"
     CDS             complement(<19689..20077)
                     /locus_tag="PKM11_05605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX48014.1"
                     /translation="MGFDYANRLKMLPPYLFAEIEEKVEKKRKEGMDIIDFGIGDPDL
                     PTPRPIVDFIKQELDDPDNHRYPSSAGEADTRRAIARWYKERFNVDVDPNGEVAILIG
                     SKEGLANICRAFVNPGEKVLAPDPAYPV"
     gene            complement(20087..20911)
                     /gene="dapF"
                     /locus_tag="PKM11_05610"
     CDS             complement(20087..20911)
                     /gene="dapF"
                     /locus_tag="PKM11_05610"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HNX48015.1"
                     /translation="MRFWKYHGLGNDFVLIENLDGSVSKDPEYVRSVCHRRFGVGADG
                     ILYLEASEKADFAMRVMNSDGSEAEMCGNGIRCLAKHVHDMGHKKDDRMTIETRSGIM
                     DIKLDVENGKAVAATVEMGAPRLECQDIPVKGEGRFVDRSFEVEGKVLHGTAVSMGNP
                     HLMIFDELTDQEMDRLGPVVHALPLFPRRTNVEFVKSMDGILDVRVYERGAGWTMACG
                     TGACATAVAAGLLGKAPLGEEVQVRLPGGSLWIKVSKDLSRVTMRGPAELVFEGRM"
     gene            complement(20908..>21348)
                     /locus_tag="PKM11_05615"
     CDS             complement(20908..>21348)
                     /locus_tag="PKM11_05615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HNX48016.1"
                     /translation="GRYIVADTTVLLTRVNDVKSTPVKQYLLVDAGFNTLIRPAFYDS
                     YHHVAVANRFGKQAEQKYDVAGPLCESGDYLAKERYLPMVEVGDVLCVYDVGAYGFSM
                     SSNYNTRPRCAEVLVADRKTFLIREREEVKDLFRHQKIPSRLNK"
     assembly_gap    21349..21448
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(21580..22935)
                     /locus_tag="PKM11_05620"
     CDS             complement(21580..22935)
                     /locus_tag="PKM11_05620"
                     /inference="COORDINATES: protein motif:HMM:TIGR00657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HNX48017.1"
                     /translation="MRKVMKFGGTSVGSGEAMSRTADIIMSYDCQRAVVVSAMSGVTN
                     SLLEMMGEGGREVPEYLDWLRQKHHDAARGNISNELMPEYLEQLEHRISGLGHLVHLY
                     RQDEDRVMYQDALASWGERLSSLTLSFILRTRGADSLALTSEEIGIVASGPPGNGSAV
                     LPATESNLRRTLSPLLNEGKVPIITGYYGADLKGRPLTFGRGGSDYSAAVVANGVDAD
                     VVEIWTDVDGFMSADPRVVKKARTIAEMDYGEAAELAYFGAKVLHPRTIEPAKRKGVA
                     VLVKNTFNPSGQGTRIHGLDRNSKELLRSVALKTGLSIVKIYSSELVYQPDLVAKILE
                     AISADGTTIYAVSTSLSTLAVVVPTGSVPEACNRLKGFRDQVEAVKVKEDAALICAVG
                     DGMLESCGVSAKIFSAVADVGANVELISEGASDIALNFMVGGSKAVDVVKRLHELYIG
                     D"
     gene            complement(22932..23711)
                     /gene="dapB"
                     /locus_tag="PKM11_05625"
     CDS             complement(22932..23711)
                     /gene="dapB"
                     /locus_tag="PKM11_05625"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: protein motif:HMM:TIGR00036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HNX48018.1"
                     /translation="MIDVTVAGATGQLGSMVCSLIREQKDMRLIGAIVSAEGGKAGTE
                     LYPGVFAVGPDGLEELCGRSTVLVDVTNAAAVERNLPLALRAGTNVVVGTTGLSKEAI
                     GRIGEMVGHSGSSALVTPNFSIGVNVFWKACQTLARALPEYEVEIIEMHHDRKKDAPS
                     GTAIKAAQLISAETGVDRMVHGREGMVGARGREIGIHSVRAGDIVGEHTVIFAGNRER
                     IELTHRAHSRLALAEGCIAAIRWIAPLRDGKVHGMDEVLGL"
     gene            complement(23733..>24401)
                     /gene="dapA"
                     /locus_tag="PKM11_05630"
     CDS             complement(23733..>24401)
                     /gene="dapA"
                     /locus_tag="PKM11_05630"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: protein motif:HMM:TIGR00674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HNX48019.1"
                     /translation="RAKVIAGAGSNATHEAIHLSRGAKDLGVDGVLLISPYYNKPNQK
                     GIFRHYEAIAKSVDVPIVVYNVPSRTGSNIAAGTIKKLSEVPNIVAVKEASGNMTQIN
                     AILASVRPDFNVLSGDDLLTFPMMALGASGVISVTSNVVPELMVQMTHAALDGDWAKA
                     RQLHFQMLPLFNDLFLDTNPIPVKTAMRMLKRPSGVFRLPLCDMETATAEVLKKTLAD
                     MKLL"
BASE COUNT         4730 a         7283 c         7207 g         4681 t
ORIGIN      
        1 acgccttcca tgaacaccct gggcaggtac tcctccttta tgccgatgcc gtcatcccgg
       61 accaccagga ccgggcggcc gccggacgag gccacggtga actccacctt ctccgccttt
      121 ccgtgccgct tggcgttccg ggccaggttc tcgatgatcg ccgtcagggc gggatccgcc
      181 agcacctttc catcgccctc gacggagtag ggcgtgtcga gaccggccat caccttgtcg
      241 atgacctcgc gaagttccat gcctaccagc tcggcctggg agaacaggaa acggtcgagc
      301 tccctcatct gggcgataat gctctgcatc ctcagcaagg aagtttgggc gcgcagcagg
      361 tccctttccc ggttgttctg cttgtacagg tccagggagg agcttatgac cagcagctcg
      421 ttcgctatat catgtcgtaa gatcttgttg gccacgccca gggattcgga caaccgggcc
      481 agccggtcct gggaatcccg cagctcctgc agaagacgga tgttggagaa ggctatctcc
      541 agggcgtccg ggatgctcat gagcatgggc agattcacat ccagtgaccg gggctgctcc
      601 acctggtcag cgcacaggac ccccacccgt ttcccccttt ccttgatggc cagagcgaaa
      661 cccttcttgg agggaaggag ctttactatc tggttgggcg ggagatgcgc cccagaggtc
      721 cacgggccgc aatcgcccag gggacggcct ccgccctccg gaaggtagca tatggagacc
      781 ggttggaaca ctccggccac catgtccatg gccgccctca tggcggactc ccggtcctcg
      841 cacccctgca acgtgcgtaa cagttccaag aactgcgggc ggctgcggtc caggtctcga
      901 tcgtcgctca tgataagcta gctgaactat cccctcggcc tataaaatcg ttacatgttc
      961 gttcaagatt ctgatattca gggaatgctg acgacggcgc tgtccgagat catttcatca
     1021 tttcgttgag taggtcgtgc accagccaga cgtccatggg accgaccaga ccgtcctgct
     1081 tcttcggacc ttccgtgcct agcggaagcc tctgacttac gccgttgatg ggcgggtcgg
     1141 aacggatcag ggtgcgaatg acgcttccca gctggtactc ttcaaaatag tagtccagca
     1201 tctccgggtc ggggatcacc gcttcgccta cacggggatg gcgaggcctc aacaatctga
     1261 ccagcagaga agacatgcca ctagggacgc ggccgagcgt attttaacgt atcgtccccg
     1321 gtgcgacaga acctccgggc gagaactagg gaagggatag accgcgcacc ctttcgcgca
     1381 tcgccaggct cgccttggcc atgcctggca aggactcctt gtccagttgg cgcaccgtcg
     1441 gaaatccttc tgggaaggtg cgggcgaact ccctgagcag atactcgtgc accacgccat
     1501 tgccgcgcag tccgtcgagc gaccaatcct ccagagcttc cagcaccccg tcccggccgc
     1561 cgcggtagaa cagctcggcc agtatggagg tcactatggc gttctcggaa accacgccga
     1621 cctccgcctc ccggagcgcg gaaagatcgc cgttgagggc gatggaaaga ccgccgctcc
     1681 tcctcaccac ctgcagcacc ctggcgtccg tctgcccgtc gcctatgtac atgcaatcct
     1741 ccagagggac gctcatgcgc ttgcatatct cgaccaccga ggtcgccttc tcatctccgc
     1801 ccaccgggtt gacctggctt atcagctgat acgaggaaag gtcggtcatc tcggtccaga
     1861 atatctcgtc caggcggcgt agcaccagcc ggtcgtccga gctcaggtcc ctgatgctgc
     1921 tggcgccttc cgggacctcc aggagcggaa gccgcacgat ctcctggacc aggttgcgca
     1981 acgtttccgt ctcccagtcc tcgaggtcca gcatgtccat gctcaggcgg gtgcagaagg
     2041 tgttctcgaa cggaaaaccg atgcgatcac agaccgcgcc cacgtaatgc tcgtaactgg
     2101 tgctgacgat gaagctggac atcagttcct ggacatagcg catggccttg tccgccccgg
     2161 gaacgatgcg tatgctgtcc ttggagaacc ggagaagcga ggaatccgtg gcgccatagg
     2221 ccttcaggaa aggcaggatc aaacgcaagg agtcgccggg tttgacgcct tccttgcgcg
     2281 acacgttgga gagcgccccc tcgtaccggc gtatggcctg gaagaggcgg tccccgttct
     2341 ccacgatagc ggtggtgagc tcccgggcgt tgtcgttggc ggtcaccggc ccctgcaggt
     2401 cggataccaa tatcttccct tcaaagggga aagcctcgtc catcatgtcg aattccgttc
     2461 agctcacctc catggtgcgg cgttggcata atggatggtc cccttatcta ggtaacgatt
     2521 ccggttcaga tatcgaagac cacccgtacc gaaggtcgga ccgggtcgac ggacatcatg
     2581 tggtacgtga tcgcctttat ctccttcttc ggctggtgcc tctgcgcatc gtacttctct
     2641 ccccaggcct tgcagtgcac ctcgttcccg aagaaggtca ccgagaaccg ggagaacacc
     2701 atgccggtga cgtcgaaaac gtagaggaac tccgacagga agttgtagag catcgactcg
     2761 tggtcgtgcc cttccgtgac catcagtctt tcctccctct cccgcacctt gctggcatcc
     2821 accatctggt ccataagggc gtaggcggcg ttggcgaagc attcctccag ggactcgccg
     2881 aaggcctcca ccatcacgtc cgcggtgtgg tccagggtac ggtacttcat gcctgcatga
     2941 tggatgatgc catttaaaag aacacgcctg ccacctgcgg ccgacccctt tcagggactg
     3001 gggcacaagg ttatatcagg gtttggcgat taagcgccga tgcgactcct catcatcggt
     3061 agcggggcca tcggaaccac tctggccgag gccatccagg acatggatga attcgatata
     3121 ttctatatca ctgacaagaa cgaggagcgg gcgaagacga tcgccgcccg gtgcaagaag
     3181 gccaagttca tatcccccac cgacgagagc atcaaggccc atctgaagaa cgtcgacctg
     3241 gtggtcgaag cggcttccca agaggccgtc cagcattacg tcccaatagt cctgggcatg
     3301 ggagtggacg tcctggtgat gagcgtcggc gcctttgctg acgacgacac gagggaacgg
     3361 tgcttcaacg tggccaagcg caagggcggc cggttgttcg taccgtcagg agccatctgc
     3421 ggcacggacg gcctgcattc cgcttcggcc gacgtgatcg acagcgtgga gctcacgtcc
     3481 actaaaggcc ccaagagctt tcacgataac gagtacctgc tgtccaaggg cgtggacgtg
     3541 aacaccctca agaagaagac cgtgatcttc gaggggccgg cccgggaggc cgtgcagcat
     3601 ttcccgaaga acgtcaacgt atcagctacc atctcgctga tcggcatcgg cctggacaag
     3661 accaaggtca aactggtctg cgacccggtg tccgactgca acacccaccg cctggaagtc
     3721 agaggggagt tcggccacat cgtttgcgag acggacaacc tgccgttccc ctccaatccg
     3781 gccaccagct atctggccgc gctatcggcc atcgccgcca taagacgcat cgccggcaac
     3841 gtttggatag gcatctaggg atttcctaaa taccgccgat tccctttcgg gcctcgtgat
     3901 agggatgaag gagcgagtga agtggatatt ctccaattgc ccgagcgatc tggacgccat
     3961 cgtcatcatg aacggtgaag agcccctatt ggacgtggcg ttcccatacg tcaccggcac
     4021 ccgggccggt cttttcgaag gatgcctggg cgtgataacg ccggacgggc gctcccatat
     4081 aatcacctcc gccctggagg agacctccgc ccgcgacggc aaggccgaag tacttacgta
     4141 ccgaacgtca caggaacgca aggacatcgc caccgacctc atgaaggcct ttcgaaaagt
     4201 gggggtgaac ggtcagggca tcgtgcactc gaactatctg gaggtccaga ggctggccgc
     4261 caaggccgag ctcatcgata tcagcaaggg actggaaacg tcccgcctga tcaaggacca
     4321 ggaggaactg cggagaatgc gcaaggcctg ctccatcgcc tcccgggtgg cggacgagat
     4381 accctccttc ctgcgcaagg gaatgaagga gtacgaggcg gcggcggaac ttgattaccg
     4441 tatgaccagg atgggcgcct ccggggcggc cttcggaact aacgcctcct tcggcccgag
     4501 ctccgcggag ccgcatcatg gggcggagga tatcgctctc aaagaggggg acaccaccct
     4561 cttcgacttc ggttgcaagg tcgagggcta ttgctcggac atcacccgca ccttcttctt
     4621 cggcgagccg aaggattggc agaagcgcat gtaccaggtg gtgaccgagg cccagcaggc
     4681 ggcgctaagc gtcataaggg ctggagcgaa cggcaaggat gtggattccg ccgccaggac
     4741 ggtgatcgac gccagcgagt tcaaggggct aatggtccat tccaccgggc acggcctcgg
     4801 cctctcggtt cacgacggcg gacggatggc cccgaaccac gatttcccgc tcaaggccgg
     4861 catggtcctg acggtcgaac cgggcgtcta catccgcggg cagggcgggg tgcgcatcga
     4921 ggacgacgtg ctgatcaccg aggacggtta cgagatgctc actgacgctg acaagaagat
     4981 gaaggtgatc caatgatgga cgaactgcag ttagcggtgg agaggatgcg ggccgaagga
     5041 gccgatttct gcgacgcccg ataccagacc ataactacga acggcatagc ggtggtcgac
     5101 gccgccgtgc gccgcatatc cgaggaccgc ataagaggcg tgtgcctgag ggccaagaag
     5161 aagggctcct ggggctacgc cacgaccgtc gattcctcca aggacgtggt cctggaggcg
     5221 gcggtgatgg cggccaggaa cgctctggcc ggcaacgccg tgggcaagat aattccggac
     5281 accggcgata tgaaggtgga gctgaaggcc aacgtgaagt tccatccttc ccaggtgccc
     5341 atggaggaga aggtgcaggc ggtcctggac atggaccggg cgcagaaggt ggacccgcgc
     5401 atcgtcaaca ccaactccat cctgcgcgag gagctgcgac agaacatgct ggtcaacagt
     5461 cacggccgcc agttgagctg ggaggaggtt cgcacgacga taatggtgca ggccgtggcc
     5521 tccgaggccg ggcgaaccga gttcttctac gacatccggg gaggcgggct tggttacgag
     5581 gtggtcaagg acaccgacct ggaatctttc ggaagggagg tcggaaagga atctctgaag
     5641 atgctcaccg ccgagaaggc gccttccgga ctgctcacct gcatcaccga ccccagcatc
     5701 tccgggctgt tggcacatga ggtcatgggt cacgcctcgg aagctgatga gatcgtgaag
     5761 aggcgctcgt tcctcaccga caaagtggga aagcgggtcg catcgccgct cataaccatg
     5821 gtggacgacg gaaccgttcc ggaggccagg ggaagcattc ccttcgacga cgaggggact
     5881 ccgtcctctc gcaccatgat catcaaggac ggggtgtacc agggttacat gcaatcactg
     5941 gagacggccg cggagatggg cgtcagaccg accgggaacg gacgagcgca gagctacgac
     6001 cgccgggtgt gggtgcgcat gaccaacacc ttcttcgata agggcgacca gaacctggac
     6061 gagatgatag ccgacgtcaa gtatggcgtc ctcaccgatc gcatgataag cgggatggag
     6121 gacccggtgg gcgggggctt tgaagccaag gcgttacgcg ggttcctcat cgagaacggg
     6181 aggatcacca agctgctgcg ctccttcacg ctcacgggga acgccctgga gatattgggc
     6241 accggggacg cggtcggcaa caaggtggag ctggacggcg gttcctgcgg caaaggcata
     6301 gaggactggg ttcccgtatc gtcgggcgga ccgcattgcc gcttcaagat cgtgctggga
     6361 ggtgactgaa tggacctgga acggatcagc aagaaatcgg tgagcaaggt cctggaggag
     6421 ggggcgaagg aagtagagtc gtacctggtg cgggtgagat cgctgaccgc gtacatagat
     6481 gacgaccggg tcaagaacct ggaggagaag ctggaccagg gcatatccat ccgcgtgctg
     6541 ctcaacggca agctgggaca atcctcttcg accttcaaca ccacccggga cctggaggag
     6601 tgcggagcga aggcggtggc tctggcgaaa ctatcccggc cggaccccta cttcaagcgc
     6661 ttcccggggt tctcacagcc agtaggtcac gtggacgtcc gccaggagga cgtggccacg
     6721 gccaccaccg gatacctgaa gcagaaggtg gaggagatag tcaaggcggc cgggnnnnnn
     6781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncggacc tggtgaacaa ggaggtgggg
     6901 aacgaactgg tgaacctgag ggaccagccc tacgaccccc gttcctccct gtcctgccgc
     6961 tacgatgacg agggcaccgt gaccagggaa aagcccctgg tagaaagagg caccctgcgg
     7021 acactgctat acgacagcta ccacgcccag atgggcaagg tggccgccac cggcaactac
     7081 ctgagacggg acccttccga cgcgctcaac ctatatcgga ggggcggggt cacgcttccg
     7141 gtgaacttgg cctggaaacc cggcacccag agcgtggagg acatgatctc ggacgtcaag
     7201 gaagggatca taatagagaa gctggccgca ccggacgtga acagcgtcac cggaggattc
     7261 gccctggagg tgcgctgcgc caagctggtt cgcgacggct ccgtggtagg gcatgtcgac
     7321 cagtgtctgc tggtcggcaa cttctaccag gcgctgaagc gagttggcgc cgtcggcaac
     7381 gacgtggcgg tgcaccgcaa ctgcatcata ccctcggtga ggttcgacgg cctggaaatc
     7441 gtgggaagcg attgatcaga ccatcggttc cagggtcacc cgggtgcggt ccgctagatc
     7501 ggacatggtg ctgacgtcgc ccagcacccg gccgatgggc gtcaccttcg aataggcctc
     7561 cggcttggac gtcgtggacg ccggggtctt cccgaagaag atgcagaagg cgttcccctc
     7621 cggccagaag gccacctcgc ccacctccat tatcttcctt ccgttctcca gcgggcactc
     7681 cacgggcacg gggaagaaaa gctccccgcc ccagacgttg atctccctct ctaacggcag
     7741 agtgccgtaa agcttgaagg cggccagtga atcgttgagc tcgatctccc aacgctcgta
     7801 acgggtgcgt aacagaatac ggtccatgcc ctttccccgg tgagggaaag ggtggacagg
     7861 tgaaaatgtt ttgcttactt cttgctctcg aagagcgcgc gtatctccgt gcccaccttc
     7921 tcgacctggc tgtcgccctc ggccttttcc aaggccttca ttcggggcat tcccttgtgc
     7981 gcatcgtcaa gccactcctt ggcgaactcc ccggagcata tgcggtccag catcttctcc
     8041 atggccgctt tgctctcttc gttgatgacc aggtccctgg tggtcaggcc accgaactcg
     8101 gcggtgttgg aaacgctcct ccacatgttc atcatgccgc cagagtagat gaggtcgacg
     8161 attagcttca cctcgtgcag gcactcgaag tacgctatct ccggctggta gcccctcttg
     8221 accagggtct ggaagccggc gttgatgagg gcggtgacac cgccgcacag cacggcctgc
     8281 tcgccgaaca ggtcggaggt ggcctcctcg cggaagtccg tctcgagcac gccggccttg
     8341 gtggaaccga ggcccttggc caatgccagg gcgatggact tcgcctttcc ggaatggtcc
     8401 tgatggaccg ctatgagcgc ggggaccccg aaaccttcca ggaagacctt ccgttccatc
     8461 gggcccgggg ccttgggggc catcatgatg acgtccacgg tcttgggggg cttgatggtc
     8521 ccgaaggtga tggcgaaacc atgggcgaac tccagcgccg ctccgctctt caggttgggc
     8581 tcgatctccg ccgcgtacac gtctccctgc acctcgtcgg gtatgagcac catgaccacg
     8641 tcggcgccct tcacggcacc ggccacggta tccaccttca gaccgttctt cttggcgtcg
     8701 acccaggact tgccgtcctt gcgaacaccg acggtaacgt caagtccgct gtcgtgcagg
     8761 cagagggcct gcgcctttcc ctggcttccg aaacctatga ccgcgacctt cttgcccttc
     8821 aggacgttga ggtcggcgtc tgactcgtga tatatccttg ccatgagatc accattgaac
     8881 gctttcacgc attttttcct gattatttac aatgttcgaa tctatcgtga ctattggttc
     8941 cagcggcagc ggttgcgtat cgtgccgtcc aggctgttca ctccgccggg gaccatgggg
     9001 agcatgtcct cctcggggtc cgtacgaatg tccagcacga acggcacatc ggacgcgaac
     9061 gcggccttga acccctcggc cagctcgctg gaccgggtga tggtcatgcc gccggcgccg
     9121 aacgcctcgg ccagcttcac gaaatcgggg ttgttgcgca gctcggtgcc gcagtagcgc
     9181 cggttccaca tcagcttctg ccactgcttc accatgccaa gccagccgtt gttgagcagg
     9241 cacaccacca ccggcaggtc ctcgctcatg gccgtggcca gctcctggaa caccatctgg
     9301 aagctgccgt cgccggctat gtccaccacc tgcttgtcgc ggtgagcgta ctttatccct
     9361 atggaagcgg ggaagccaaa gcccatggtg cccattccac cggaggtcac gaactggttg
     9421 gggctcttca agcgcatgaa gtgcgccgcc cacatctggt tctgtcctac ctcggtcacc
     9481 acgaaggcgt ccgaagaaag ggccttgcgc agctcccaga tggccttctg cggcttcacc
     9541 gggtcctcgt cgatatcgat gttgcacacg caaccgtcgt acagctcctt cacccggcgg
     9601 ctccaggccg tctcggcctt gttggagcgg cccagggcct tgatgaccat ctgcagcccc
     9661 ctcttggcgt cgcccaccag gcgcaccttg gtgcgggcgt tctttccggc ctccatggga
     9721 tcgatgtcca ggtggatgac cttggtgtcc ttgggaacct cgttgtcgta accgatggtg
     9781 cggtcggaga accgggcgcc gatggcgaat atcacgtcgg cctccaggag cgccctccgg
     9841 gagcattccc gcccgtgcat gcccagcata ccgaaggaca tgggatggtc ctcggggatt
     9901 atggccttgg ccattatggt ggtgaccacc ggagcgagca gcatctccgc cagtctcagt
     9961 acctcgctgg aggcgttggc ccatctggcg ccgcccccga ccatcagaac gggacgctcg
    10021 gcgtccctta gcatcttgac cgcgtccaga accgccgaga agtcctcata gggcgccggc
    10081 accgggaagt tctcctgcag cctggccggg tcgatctcgc cgcgcagcac gtccaccggc
    10141 aggtcgatgt gcaccggacc tttgcgtccg ctgttggcga tgcccatgcc ccgctttatg
    10201 gcctcgggca gatcgttcgg cttgagcacc cggtagttgt gcttggtgat gggcatcatc
    10261 aggctgaaga tgtccgcttc ctggaaggca ttgttcccta tggcggccgt ggccacctgg
    10321 ccagtaagca ccatcatggg cgaggagtcc gcgtaggccg tggccacgcc ggtcaccagg
    10381 ttggtcgccc ccggtccgga cgtggccagg cacactccgg tcttggaggt ggtgcgggag
    10441 tagccgtccg ccatgtgcgc cgcgcactgc tcgtggcgga ccaggacgtg atggatgcta
    10501 gaatcgagca gctcatcgta caatgggatg gtgaccccgc ccggatatcc gaacatgacg
    10561 tcgaccccct gtccttcaag cagttccaat acggccttgg cacctttcat aagctaatcc
    10621 ctcattttcc gatcggggag gacggtcgtt agacctcctc tttcacaaaa taacaacggc
    10681 agtgagcgat ggtaaaaacg acgactttct cacacgcgtg ctgttatatg acacggattc
    10741 agttcatgcc gagcaagata tttaagaata tctcagacca tcctcgttct cgaggacagc
    10801 tgggaagggc cttgggatgg tgtctattaa attgccagat gatgaaaggg acatcgtgga
    10861 gctaagggac cacgatcccg tttggaagga cctctttcaa ttggagaggg cgtccctgct
    10921 caagtccctg ggaccattgg cgatgaccgt cgagcacgtg ggcagcacgg ccgtccccaa
    10981 cctccgggcc aaacccatca tcgatatcct ggtgacggtc aacgagatcc gtctggatgc
    11041 attggaggac tcgttgggaa ggttaggtta cgtccacgta ccgatcggcg atcccgagcg
    11101 gctgttcttc cgcaagggaa tgccgcgaac gcatcacgtc catgtggtac gtcatggagg
    11161 gaacgagcat cgcaagcacc tcatcttccg ggaccggctg atcgcccatc cggaagagtt
    11221 ggcggaatac gagagactga aggaatccct cgccctgcgc ttccgggagg accgccaggc
    11281 ctactccgac ggaaaggatg ggttcatcgt gatgatactg gatagggcaa aggacgaacg
    11341 tcgttccaag acctgatgga tcgaacgagc acgccaaact catatattgc cagtgaacgt
    11401 tcccttccag gtcaggagag tgaccatacg agcgccaagg aattgatgga gaacgggtcc
    11461 cgcagcaagc ttctggaaga tccgttcgtg aagaaggtgt gggacctgat catgggcgag
    11521 tcgctcttca agaagagctc agcggagctg gcatcgctca gggaatcgtt gcgccgggag
    11581 tccttgcagt tcttcaccag gcacagccct tactacgtgg acctcttcga gcgcctggat
    11641 atcgacccgg ccaaggccac gatgcatgac atcgccaagt tggcgatccc ttccgacatg
    11701 ctgcgcggcg agggacagaa gcgcttcctg atccaggatg tggaggaagg cggggaaacg
    11761 ttctcttcca gcggcaccac cggtaaggac ccggttcggg tgtaccgatc accggtcgac
    11821 ctggccatca tgctcaaggc caacaccgac ctcttcgagc atgtctacgg cgatgttctg
    11881 aaggaagggg agggcgtcgc cctcttcatg gccgctcccg agctccgcta caagctgagc
    11941 ttcgtggcct tcgtcgatct gacgttggac aagaagggca tcgagctgct ttatggaatg
    12001 gacctggaag ataaatcgca ggccggaacc ccgtggcaga agctgaccac caacaaggag
    12061 aacctgttga agttcctcaa gtcgaagaag gagcccaagc tgttcttcac cgccccggcc
    12121 ggagttcaca tcctgggcca gaagttcgag accatgggcg tcgggaagaa gatagcatac
    12181 aagctggcct cgggagcgcc gccgatcaag ctgggcaagg gaggaatcat cgtcaccggc
    12241 gggggaagca agggcttcgc cgaccttccg gaatacccgc agctggtctc caacgcccag
    12301 aagcatttcg tcagcaagga cgctgacgga aagcagatcg acaccccgtt catggacgtt
    12361 ctgggaatga ccgaaacgct caccgccctc atcgaccgtt acggggtgac ggacaaggtg
    12421 cctcatccgt tggccgaagc gttcctgctg gaccccctga ccttcgagcc gatcgaggag
    12481 gagggaaagg aagggatatt aggaatattc aaccccttca ccacctcctg gctggaggtg
    12541 ttctaccccg gggacataat gacctaccat tcctccaagg gattctacgg caaggagttc
    12601 gtctacaagc gccggnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnataga
    12721 tgagaggctg caggtcatcg agcacatcgc ccggaagtgg aagcagaagc tggacaacgg
    12781 tgatctcgag gaattgaaga gggacatgtc cgcctccacc ggctactccc cagcgttgat
    12841 ggagaccgag ctctctttcg tcccggcggt gctgggggcg gcgaacatcc gccggaacct
    12901 ggacgcctcg gtgcagggcg gcgctgacgc gctgtacaag ttcgtggagg tggacgagac
    12961 ggagatgttc cgtcatgtgc cggtcggtcc ggtgctgatc atcagctccg gcaattccat
    13021 cgttccgacg ctcatcccca ccgtggtctc gttagtaact ggcaacctga ccatcctgaa
    13081 gccgtcgatt gccaactacc gcggggtgtg cgaggtcttc aaactattgg ccgaggttcc
    13141 cgattcccgg gcggcccggg ccgtccgctc cgctctagtc gtctcgtact tcggtcacga
    13201 ctcgccctcc ttgaagctgg ccctggagga actgccgctg ggcatggtaa acttctgggg
    13261 cgcggaacct gctcggacca tcgtggccaa catggtcggc aagaaccgcc atcacccgcg
    13321 cttcttcgtc aatgggccgt tcaccggcat ggccatcatc gaggagggtg ttgaaccgtt
    13381 gcaggcggcg gacgacctgg ccctggatgt cgtgctctac gatcaacagc tgtgctcctc
    13441 gcccaccacc ggggtgttca ttggcagtta cgatagggcc aaggagttcc tgagggccgc
    13501 cggagaacgg ctggacgagg cggggaacga atttccgctc ccaccggacc aggaccgcct
    13561 gttcgtcctg cagggcgcca gacgatacat ccagacggac gggggaatgg tgctttcctc
    13621 caagaacccg gagaaccctt ggacgctcgt gctgtccaag ggccgcagct ccctggccgg
    13681 actggccgcc cagttcccgg ccttcaacct ctttgcgaga aagcgcttcc tggagatcgt
    13741 ggtggtcccg gacgcggaga gcgcggtgca gctgctgcgt tcattgccgg accacccggc
    13801 cttcaaaggc atcgacgggg tgcagagcgt tggtctggcg gtgaccgaag ggtcccgcga
    13861 tcctatggtc aacatgctca tcggggccgg ggtgcaccgg atacttccgc tgggggacat
    13921 gttcatgcgc ggtgccgtgg aaccgtacga tggggttacg atgtcctcgc tgttcacccg
    13981 catcgtgtac tggcgtaaag cgaacgtagc cctggagggg caactttgag agttttggtc
    14041 accggagcca ccggattcct gggcggacat ctgatcgagg agatgtccaa agggcctcat
    14101 gtcccggtat gcgcccaccg ccagggaagc gacaccaaga ggatcgacga gctcgggctg
    14161 gagaaggtgg tcttcgacct caccgaccgg gactccatgc tccaggccct gaggaacgtg
    14221 gacgccgtgg tccacctggc cgcgtactac acgttcaccg gaaagaagga gatgtacgag
    14281 aaggtcaacg tcaagggaac ggacgacctt ctgaaagcgt gccaggagac tggcgtgaag
    14341 cgtttcctgt actgcagcag caccgaggcc atgggaccga tagagtctcc cccgggggac
    14401 gaggattcgc cacttaatcc gcagtacgag tacggacgct ccaaggcccg ggcggaggag
    14461 ctggtcagaa cgtccgatct ggactggacc atcctgcgtc cgtcgggcat ctacggcccc
    14521 agcaacgtgg acgacgtggc ctactttttc ataacctcct tcaagggatt cgcctccaag
    14581 ttcatcatcg ggtccggcaa gaacttcatc cagttcgtgc acgtgaagga tgtggtgcag
    14641 ggattcgtga aggccttgga ccgtcccgcc tcaatcaggg gaacgtacat catcacccag
    14701 gccaggccgt acacctacga ggaggtgtac cgggtcctgg ccaacatatt ccagcagaag
    14761 gagccgcgtt ggcgggtgcc gagatcactg gccaagctga tgatgctgcc catagagggc
    14821 ttcagccttc tcttcggccg ggagaacttc ctctaccgac gggagaccgt gaacagcgtc
    14881 acgagcgata gggcgtacaa gatcgatcgc gcccggcggg acctggggta cgaacccata
    14941 tacgacctac cggaaggcat ggcggaaacc gtggcatggt accgagagaa cggctacctc
    15001 tgagcaacga ttaaatccgc tatcgttttt aaccgtcccg gtgagaggat ggagaagacg
    15061 ctgtaccgca ccctgctgaa catgctgagg atcagctaca ctctgccttt cgtcatggcc
    15121 tcggtgaccg gggcggcgtt cgcgctgacg gtctgcaacg aatggtcgct cgccatcctc
    15181 attcctctgg acatattctt cttcgccctg ttcgccaacc tgagcaacga ttacttcgat
    15241 cataagagcg gcaccgacgc cacccgcttc gatttcatga ccgaggagag caaggaggcc
    15301 atcaaggagc tttacgacga gcgcatatac tgggatggca acatctttga caaaggggac
    15361 gtcagcgaac ggaccggcaa gatagttctg gccgtcattc tggccatggc cttattgacc
    15421 gctctgccaa taattttgca cggcggctgg ctcgtggtgg tgctaggagc cataggccta
    15481 ttcctggcgt acttctatac cgctcccccg ctgaacctgg gcgcgcgtgg actgggcgag
    15541 ctggacgtcg ggacctcctt cttcatgatg tccttcttca cctactacgt cataaggccg
    15601 gaatggaact ggcagatgtt cctgatcgcc ttgatcgtgg gaacgtccgt gctgctgatg
    15661 cgcttcgtcg atcagatgtc cggctaccag gcgcacctga agggcggcga gaaggattgg
    15721 acggtgaggc tgggactgga aagggcggtg gtagcggttg gtattatcct gctgttcgtc
    15781 cacgtcatgc acctggcgct cgtctacttc cacccggtgt tcctgatcct cttgctcacg
    15841 gtccccatgg gaaggaagct gatgaagggt cttcacgaca aggacgatgc cctgcgcttc
    15901 atccggcccg cgccgcagat agtgaagatg gtcatcttca gcgagctgtt gatggtcatt
    15961 tcgttgatag tccaaaacgc cctgccatgg acaatatggt agtgacgctg cccctggtta
    16021 tcagcgagta ctcgcgcacg gcgttgaagc cgcattgctt gcatgattcc cccttcatgg
    16081 ggcagccgta cagcttgctg cggtccggca tgatgaactc cgaggcccag aacgggcatc
    16141 ttcccgagta gtcctcgatg agaagctcct tcagcccctt cttggagtta aggatgggat
    16201 agccttcctt cttgagggtg aatatctcct ccaccacctt gcgcttctcg tccaggctga
    16261 ggagcttgga ccccgggggc ggagtgagga agttaatcat cagaccgttg atgcgcgggt
    16321 tgtccttcac cacctgcgcc gtctcccgga tgagatgctt gttctcgggc atgaccacca
    16381 tgttggcgaa cacgttggga tggtccacct tggataggtt ctccatcaac ttgtcgaaga
    16441 cgccctcgca gcggatggcg tcgtgcacct cccgcggccc gtccagtgag accgatatga
    16501 cgtcgctctc cagatagaac acgttggtgc cgttggtggt gtacccgatc acgaagaacc
    16561 ctgcatcctt tccggccttg atgaggtcca ggagcgtgcg ttccccgtcg ctccagctgg
    16621 ttggctcccc accctcgaag aatagtacgc gggccccacg gtcgtaggag gcctgcatct
    16681 cctccaccgc cacctggtac ggcatcttgt gcggctgcgg catggatggc aggttctccg
    16741 ctatctgaca gtgctggcac cgaaggttgc actgataggt gatgatcatg gtggtggcca
    16801 ggggcttctt gaaccccagc agctccttga ggaaccagat gccatagtag gcggtctggc
    16861 cgacggtcct cgctacgccc atgccctacc catccccgcc ccgatatttc aattgtgccc
    16921 ggcttcgttc gccatggtcc tcgccactat agttttagaa gaccctggac aggtattgcg
    16981 catctaaaat tttgtaccga cccagacaag ttttacaaag tgtttgcaat tctgataatc
    17041 attaaatact ggccaactgg tcccatttta aactatttca taggagtgat tcaatggcaa
    17101 gtttgaagtt agaaatcatg gacaagatcg tggcccttat gaccgcagca ttcggtttcg
    17161 tcgctgcact ggcctggaac ggcgccatct cgcaattgat gacggactgg ctgggagaga
    17221 gcggagatgc gaccctgggt ctcatcatat acgccgttat cgtaaccatt gtggccgtta
    17281 tcgccatcgt cctgatctcc agggtgtacg gcaagatcaa gtccaaggaa gaagccaagg
    17341 aagctgcgaa gaagtaaact tcttttggca aaccctttaa tctcttcctt tttttgtaat
    17401 ccttccacca ttgttctcgt cataccaaaa cgatgataac cgcccttggc tatcctgaaa
    17461 acgcacagga ggcttcgcat gaaggtcaag gtagggatca acggttatgg cacgataggc
    17521 aagagagtgg cttgggctgt gaacaggcag gacgacatgg agatcgtcgg ggtcacgaaa
    17581 acgcgcccct cgtacgaggc ctcaacggcc ataagggaag gctgtccact atatgcggcg
    17641 cacgccgagg acgttgataa ttttgagagg gccggaatac aggtccaggg caccctggaa
    17701 gacctgctga agaaggtcga catcatcgtg gactgcacgc ccggcggcat cggggccaag
    17761 aacaaggagc tgtacgataa ggccggtgta aggtccatat tccaaggggg cgaggatcac
    17821 gccatggccg ggatatcgtt caacgccctg gccaattacc acgaggcnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn nnnnnnnnnn nnnnnnncgg ttccaccctg tactattacc aggccgtgca
    18001 ccaggagagc gacgtggtcc cggagaacgt ggactgcata agggccatga tgaagctgga
    18061 gaaggacaat ctcgtctcca tacggaagac caacgcggcc atcgggctgg actgatacct
    18121 gccgtaaaaa gtcccgcgct tccagtcgga ggccgggcaa atcatttttt atcccatcgc
    18181 catccgtgtg ctgtaagtat accactgtcg cggacctgac cgccagggga atttgccatg
    18241 aaggaccact tcaccatcga cgacctggac atcaagggga agaccgtcat ctaccgcgtg
    18301 gacatcaact gcccgctgaa gaaggacacc ctggaactgg ccaacgacaa ccgcatccag
    18361 gagatattgc cgaccttgcg ggagcttttg aagcgccggg ccaaggtggt catcgtcgcc
    18421 caccagagcc ggccggggga gtgggattac atttctttgg aacggcatgc caagcgcacc
    18481 tcggaactgc ttggggtgga ggtcgtgtac gttgacgacc tctacgggga gaaggccaag
    18541 aaggtcatac agcgcatgat gcccggcgag gcggtgatgc tcaagaacgt ccgggacgag
    18601 aagggagaga tggacaaggc cagcatggag gagcattccc aagccccgtt ggtgaaggag
    18661 ctgtccgccc tggccgacct ctacgtttcc gatgcctttg gggcggccca ccgctcccaa
    18721 tgctccctgg tagggttcca ggccgtgctg ccgtcggccg ccggccggtt gatggagaag
    18781 gagctgaccg ccctcggccg ggtcatagac tcgccgtcgc acccctgcgt tttcgttcta
    18841 gggggttcca agttcaccga cgccataaag gtggtcgatc gcgtgcttcg cgagaacatc
    18901 gccgacaagg tcctgatggt cggactggcc ggaaacgctt tccttaaggc caagggcgta
    18961 tcgctcgggg agaagagtga gcacattctc atggaagagt tcaccgccga gaacctgaac
    19021 gcggccaaag gcctgctgga ccgctacggc gatcgcatcg agaccccggt ggatgtggcc
    19081 ctggacgacg gaggcatgcg gaaggacgtc cccatcggcg cgttgccttc cgagctgccc
    19141 atctgcgaca tcggcaagga gaccgcggcc cggttctcag agatcgtctc caaggcctgc
    19201 acggtgttca tctccggtcc ggccggggtc atcgagcggg aggagttctc ctacggaacc
    19261 aaggcgctca tggaggccac ggtgtcctcg gacgccttct ccgtgatagg cggtggacac
    19321 acggtcagcg ccgcccagag atatcattgc tgcgaccgat tctcgtacgt cagcaccggc
    19381 gggggcgcat tggagaacta catcatgggc aagccgcttc cggtcgtgga ggccctcaag
    19441 gccgcgtata gaagggaaaa ggggaagtag tttctcagag gaccttggac atccgttcca
    19501 aggcctcctc gatgcgcttg accgactggg tggtggccaa tcgaacgtaa ccttcgccgt
    19561 tctttccgaa accgacgccc ggagtgacnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19681 nnnnnnnnac gggataggcc gggtcgggcg ccagcacctt ctcgcccggg ttcacgaagg
    19741 cgcggcagat gttcgccagg ccctccttgg aaccgatgag tatggccacc tccccgttgg
    19801 ggtcgacgtc cacgttgaag cgctccttgt accagcgagc gatcgcccta cgggtatcgg
    19861 cctccccggc gctggacggg tagcggtggt tgtccgggtc gtccagctct tgcttgatga
    19921 aatccactat cggccggggt gtgggaaggt ccgggtcgcc tattccaaaa tcaatgatgt
    19981 ccatgccttc ctttctcttc ttctccacct tctcttcgat ctccgcgaag agatatggag
    20041 gcagcatctt caaccggtta gcgtaatcga atcccatatc cgtccctcac atccgccctt
    20101 cgaacaccag ttccgcagga ccgcgcatgg tcaccctgga caggtctttc gagaccttta
    20161 tccacaggct tccgccggga aggcgcacct gcacctcctc tccgagcggg gctttgccca
    20221 gcagtccggc cgccacggcc gtcgcgcagg ctccggtccc gcaggccatg gtccacccgg
    20281 cccctcgctc gtacacccga acatccaata tcccatccat cgatttaacg aattctacgt
    20341 tggtccggcg ggggaagagc gggagggcgt gaaccaccgg tcccaggcga tccatctcct
    20401 ggtcggtgag ttcgtcgaaa atcatcagat gggggttgcc catggacacc gcggtgccgt
    20461 gcagtacctt tccttcgacc tcgaacgacc gatcgacgaa acggccctct cctttcaccg
    20521 ggatatcctg gcattccaga cgcggcgctc ccatttccac ggtggccgcc accgccttgc
    20581 cgttctccac gtccagcttg atgtccatga tcccggaccg ggtctcgatg gtcattcggt
    20641 catccttctt atgacccata tcgtgaacgt gcttggccag gcaacggatg ccgttgccgc
    20701 acatctccgc ctccgagccg tcggagttca tcacccgcat ggcgaaatcc gctttttcgc
    20761 tggcctccag gtatagtatc ccgtccgccc cgacgccgaa gcggcgatga catacggaac
    20821 gaacgtactc cgggtccttc gatacgctgc cgtccaaatt ctcgatcagc acgaagtcgt
    20881 tgcccagccc gtggtacttc cagaacctca tttgttcagc ctcgacggta tcttctggtg
    20941 acggaagagg tccttgacct cctcccgctc ccggatcagg aaggtctttc gatcggcgac
    21001 cagcacctcg gcgcagcgtg gcctggtgtt gtagttggag gacatggaga agccgtaggc
    21061 gcccacatcg taaacgcaga ggacgtcgcc gacctccacc atcggcaggt acctttcctt
    21121 ggccagataa tcaccgctct cgcacagcgg accggccacg tcatacttct gttcggcctg
    21181 tttcccgaac cggttggcga cggccacgtg atgatacgag tcataaaagg ccgggcggat
    21241 gagggtgttg aagccggcgt cgaccagaag gtactgcttg accggggtgg acttgacgtc
    21301 attgactctc gtcagcagca cggtggtgtc ggcgactatg tatctgccnn nnnnnnnnnn
    21361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    21421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnat cgcgcggtag ttctcccgca gggcgttctc
    21481 atcggtgacc atcaagggag ttccgaaccg ctgagcgagc ttgacggccg agacgccgcc
    21541 gatgatcatg ttgtcctttc tcttctggaa ttctctcatt caatcaccta tgtagagctc
    21601 atgaagtctc ttgaccacgt ccacggcctt ggagcccccg accatgaaat tgagcgcaat
    21661 gtccgaagcg ccttcggata tcagctccac gttggccccc acgtccgcca cggcggaaaa
    21721 tatcttggcg gagacgccgc agctctccag cataccgtcc ccgacggcgc agatcagggc
    21781 ggcgtcctcc ttgaccttca cggcctccac ctggtcgcgg aagcctttca acctgttgca
    21841 ggcctccgga accgacccag tgggaacgac cactgccagt gtcgacaggg aggtcgatac
    21901 cgcgtagatg gtcgtgccgt ccgcgcttat ggcctccagt atcttggcca ccagatcggg
    21961 ctggtacacc agctcggagg agtatatctt cacgatgctc agcccggtct tcagcgccac
    22021 gcttctcagc agctccttgc tgtttcgatc caggccatgt atgcgcgtac cttgcccgga
    22081 aggattgaag gtgttcttca ccaggacagc cacgcccttg cgtttagcgg gctcgatggt
    22141 ccgggggtgc agtaccttcg ctccgaaata ggcgagctcg gccgcctcgc cgtagtccat
    22201 ctcggcgatg gtgcgggctt tcttgaccac ccggggatcg gcggacatga aaccgtccac
    22261 gtccgtccag atctccacca cgtccgcatc cacgccgttg gcgaccaccg cggcggagta
    22321 atcggaaccg ccccttccga acgtcagcgg gcgccccttg aggtccgcgc catagtaacc
    22381 ggttatgatg ggcaccttgc cttcgttgag caatggcgag agagtccgac gcaggttgct
    22441 ctcggtggcc ggaagcacgg cgctaccgtt ccccggaggg cccgaagcga caattccgat
    22501 ctcttcggac gtcaacgcca aagaatcggc cccgcgggtg cgcaatatga acgagagggt
    22561 gagcgatgac aagcgctcgc cccaactggc cagggcgtcc tggtacatca cgcggtcctc
    22621 gtcctgacga tagaggtgaa ccagatgccc caggccggag atccggtgct ctagctgttc
    22681 caggtactcg ggcatgagct cgttggatat gttcccacgg gcggcgtcat gatgcttctg
    22741 tcgcagccaa tcgaggtact ccggcacctc ccttccacct tcgcccatca tctccagcaa
    22801 ggagttggtg accccggaca tggccgagac gaccaccgcc ctctggcaat cataggacat
    22861 gattatgtcg gcggtgcggg acatggcctc gccagagccg acgctggtgc ccccgaattt
    22921 catgaccttt ctcatagacc tagcacctcg tccatcccat ggaccttgcc gtcccgcaga
    22981 ggagctatcc aacgtatggc ggcgatgcag ccttcggcca aggccagacg ggaatgcgcc
    23041 cggtgcgtga gctcgatccg ctcccggttt ccggcaaaga tgaccgtatg ctcgccgacg
    23101 atgtccccgg cgcggacgga atgaatgccg atctcccttc cccgggcgcc taccatgcct
    23161 tcccttccgt gcaccatgcg gtccacgcca gtttcagcgg atatcagttg agcggccttg
    23221 atcgccgttc cagagggggc gtccttcttc cggtcgtgat gcatctcgat gatctcgacc
    23281 tcgtactcgg gaagagcccg ggctagcgtc tggcaggcct tccagaagac gttcacgccg
    23341 atggagaagt tcggcgtcac cagggcggac gagccgctgt gtccgaccat ctcgccgatg
    23401 cgccctatgg cctcctttga taatccagtg gtgccgacca ccacgttcgt tccggcccgc
    23461 agcgccaatg gcaggttcct ttccaccgcg gcggcgttgg tgacgtccac cagcaccgtg
    23521 ctgcgcccgc acagttcttc cagaccgtcc ggtcctacgg cgaaaacgcc cgggtacagc
    23581 tcggtgccgg ccttgccgcc ttccgcggag actatggcgc cgatcaaccg catgtccttc
    23641 tgctccctga tgagggagca caccatggag cccagctggc ctgtggctcc ggctactgta
    23701 acgtctatca tgtcttggag cctccttttc gctcagagca gcttcatgtc cgcgagcgtc
    23761 ttcttcagaa cctccgcggt ggcggtctcc atgtcgcata gcggcagacg gaaaacgccg
    23821 gacggtctct tgagcatgcg catcgccgtc ttgaccggga tggggttcgt atccaggaac
    23881 aggtcgttga acagcggcag catctggaag tgcaactggc gagctttcgc ccaatccccg
    23941 tccagagcgg cgtgggtcat ctggaccatg agctccggga cgacgttgga ggtgaccgag
    24001 atgacaccgc tggcgcccag ggccatcatc gggaaggtca gaaggtcgtc cccggacagc
    24061 acattgaaat cgggacggac gctggccagt atggcgttga tctgggtcat gttcccgctt
    24121 gcttccttca ccgccacgat gttcggcact tccgacagct tttttatcgt tccggcggcg
    24181 atgttggatc cggtgcggga cggcacgttg tagacgacta tgggaacgtc caccgacttg
    24241 gctatcgcct cgtaatgacg gaatatgccc ttctgattgg gcttgttgta atagggagat
    24301 atgagcagca ctccgtccac cccgaggtcc ttggcccctc tggacaggtg tatggcctcg
    24361 tgggtggcgt tgcttcccgc cccggcgatg accttggccc t
//
LOCUS       DAOPZI010000023        22502 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_2331_length_22502_cov_9.852452, whole genome shotgun sequence.
ACCESSION   DAOPZI010000023 DAOPZI010000000
VERSION     DAOPZI010000023.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 22502)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22502)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22502
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2331_length_22502_cov_9.852452"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(100..372)
                     /locus_tag="PKM11_05635"
     CDS             complement(100..372)
                     /locus_tag="PKM11_05635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48020.1"
                     /translation="MKFRVERICRSDSMSAIPLDHVRFDLMLSGDALRAKGYEVEAQE
                     LFLITKVGQMDVTIYGSGRVLVHPLNDKAKAKELAQTLFEILVPER"
     gene            complement(369..899)
                     /locus_tag="PKM11_05640"
     CDS             complement(369..899)
                     /locus_tag="PKM11_05640"
                     /inference="COORDINATES: protein motif:HMM:NF024605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HNX48021.1"
                     /translation="MGVLILTGMPGAGKEELVSVALELGYQVRRMGDVVRAEALRNGI
                     PPQEVGKFAHEERQRHGYDIWAKRIVPLVGEGDTLIDGCRGMSEVSVFREAFGTHVKV
                     MAVHSSPSTRFPRLVSRGRSDAPRDRQEFDERDKRELSWGLGETIALADALIVNESTL
                     ERFRADAFVVLRELKG"
     gene            complement(937..1398)
                     /gene="pyrI"
                     /locus_tag="PKM11_05645"
     CDS             complement(937..1398)
                     /gene="pyrI"
                     /locus_tag="PKM11_05645"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HNX48022.1"
                     /translation="MKEFKVTPIRNGTVIDHIDCGMALKVLRIIGMTDGGKVQSPVSV
                     LMHVPSKKEGWKDVVKVEDRELDPREVDKIALIAPKATINIIRDFNVAEKYSVKMPER
                     VVGKAKCSNPNCITNQNEPIEPEFVVESKNPPMLRCVYCDRQLDDIAGNLL"
     gene            complement(1398..2327)
                     /gene="pyrB"
                     /locus_tag="PKM11_05650"
     CDS             complement(1398..2327)
                     /gene="pyrB"
                     /locus_tag="PKM11_05650"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HNX48023.1"
                     /translation="MTFEGMDIVSIRDLTREQIEQVLERSERMIPYARGEMSSKALDG
                     KILATLFFEPSTRTRMSFESAMMRLGGRITDLGVPSMSSISKGESLADTIRMVEVYSD
                     IIVIRHPREGSARLAARFSSKPVINAGDGAGQHPTQTLLDLFTIKRIKKDFSKLKVVM
                     VGDLKYGRTVHSMAEALSSFGVDLTFVAPAALQMPKETVKQVEKAGGKPKLTSRLEET
                     IAEADVLYVTRIQKERFPDLAEYQKVAGMYRVDKKLLREAKSDLIVMHPLPRVDEIDP
                     EVDGTPHAKYFEQAFNGVPVRMALLNLVLGGEL"
     gene            complement(2433..2795)
                     /locus_tag="PKM11_05655"
     CDS             complement(2433..2795)
                     /locus_tag="PKM11_05655"
                     /inference="COORDINATES: protein motif:HMM:NF014080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX48024.1"
                     /translation="MMPESIKDVNSCQDLVQCAYSLNGFEVEVYERLLETGPVNANEL
                     ADLMGKDRSTVYRALQKMMTCGMVLRETRSIPRGGYFHVYRAISRKELREKLESCVEN
                     WYKKMQGALQKFESSDAD"
     gene            2858..3115
                     /locus_tag="PKM11_05660"
     CDS             2858..3115
                     /locus_tag="PKM11_05660"
                     /inference="COORDINATES: protein motif:HMM:NF013379.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HNX48025.1"
                     /translation="MQNRYMVIIMDKKETLDAKGLMCPMPIVKLAKKMKEMKVGEVLE
                     LIADDVGSKEDVPAWCKRTGNELVSQKEEGGAFFFYIKKVQ"
     gene            3143..3553
                     /locus_tag="PKM11_05665"
     CDS             3143..3553
                     /locus_tag="PKM11_05665"
                     /inference="COORDINATES: protein motif:HMM:NF025066.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/DsrF/DrsH-like family protein"
                     /protein_id="HNX48026.1"
                     /translation="MAETKKFAMVVAEGTFDKAMMAMMMGNTAASMGIETHIFYTFFG
                     LNLLKKGAKPKMPGMMRFFTGMMIKKMKGIGLDGYQEQLEMAKELGIKIYACSTSMEL
                     MGIKKEDLIDGVTVLGAAAFLDIGTDADMQLFIG"
     gene            3564..3863
                     /gene="tusB"
                     /locus_tag="PKM11_05670"
     CDS             3564..3863
                     /gene="tusB"
                     /locus_tag="PKM11_05670"
                     /inference="COORDINATES: protein motif:HMM:TIGR03011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HNX48027.1"
                     /translation="MKSKLFITLKSPHEFGGLELVRSSAKGAKSALLLFEDAVIFAAN
                     AKMGKELLSAVQDVYVMKDDWEARGLPLAVPGFKIVDYPEAVELIMERYEQTITV"
     gene            3873..4229
                     /locus_tag="PKM11_05675"
     CDS             3873..4229
                     /locus_tag="PKM11_05675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HNX48028.1"
                     /translation="MKTMVIQIRSGTMMNMDTNIAVKLAQAALDKGYNVRMFGYGEAV
                     TIIKNGQDPKRFPNVGKETKELLGKGLEVVVCETCCKARGILRGEEIEGTKIGSLTND
                     LSRFVAEGDRMVTIAR"
     gene            4235..4594
                     /locus_tag="PKM11_05680"
     CDS             4235..4594
                     /locus_tag="PKM11_05680"
                     /inference="COORDINATES: protein motif:HMM:NF014672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HNX48029.1"
                     /translation="MAQSLLILVTKAPYGFEEAFAGLRAGLGMLASGQVPVSNALLVG
                     EGTLNAVAAQKPEAVRMPSNAEAINDLLEFEAKVYVVKEDLLHLVGDVPLLEGVELID
                     WERARQVIDEHDMVTTF"
     gene            4653..>5281
                     /locus_tag="PKM11_05685"
     CDS             4653..>5281
                     /locus_tag="PKM11_05685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48030.1"
                     /translation="MLELLARSGTARRCLWSLEGAKVETPGAFVVEGGAEGLALELAD
                     GSSVLQMNGRTVLEMTGNGLLAPLKARGGMKDSCLPPVSDAQEIAVLDGAFELRRDAR
                     AFVRALVELRTSVGRSKLIYAPGIAETSNLAILSYLGVDLFDTSLIDHRAAIGELSLV
                     EGPMLASKADWVPEGSDLRAMNRENMFRELALVRGMISSGRMREFAEMR"
     assembly_gap    5282..5381
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5382..5975
                     /locus_tag="PKM11_05690"
     CDS             <5382..5975
                     /locus_tag="PKM11_05690"
                     /inference="COORDINATES: protein motif:HMM:TIGR00451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="queuine tRNA-ribosyltransferase containing PUA
                     domain protein"
                     /protein_id="HNX48031.1"
                     /translation="MASQGYDHVILHLGDEGPIIQEVLDGTITSNGSPTSNESLGMLK
                     ETLTELCSRYDRVDPSKDRWAAMSSVAGFQFGPGGEALLDEAYILGNYPFMKIMAHKE
                     QLGMLNPERGMISLTVEGAEAILPLIPKVTMGDFELKGSLFAVGVSDADSSIRAGEEV
                     AIMRNGKIVGVGVASMGGREMVEMRRGEAVKVRHKRK"
     gene            6349..6882
                     /locus_tag="PKM11_05695"
     CDS             6349..6882
                     /locus_tag="PKM11_05695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TATA-box-binding protein"
                     /protein_id="HNX48032.1"
                     /translation="MQNVVASANLGTELDLTELALNLNGAEYEPETFPGLIFRLKEPK
                     TATLLFRSGKLVCTGATNLEDVKKAVKTVVASIRKAGVKVEAVPPVTVQNIVASADLG
                     QPVNLSSVVITLGLDRVEYEPEVFPGLVYRLTEPKVVILLFGSGKLVCTGAKVPEDVE
                     AAVTKIKNELRAENLLL"
     gene            complement(6960..7031)
                     /locus_tag="PKM11_05700"
     tRNA            complement(6960..7031)
                     /locus_tag="PKM11_05700"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6996..6998),aa:Gly,seq:tcc)
     gene            complement(7180..7356)
                     /locus_tag="PKM11_05705"
     CDS             complement(7180..7356)
                     /locus_tag="PKM11_05705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48033.1"
                     /translation="MRRNEGSFSEQMYDGHAVEWMKTHTIQDLKLMAFELDQQGQETM
                     ELWDLINDLKIMSL"
     gene            7592..11887
                     /locus_tag="PKM11_05710"
     CDS             7592..11887
                     /locus_tag="PKM11_05710"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HNX48034.1"
                     /translation="MGLFNNLLDAEARAVKKAVRSLDVADKHMQAKETDKALVEADKA
                     RVALEGLDPKAVVNLNDYRTAISRISNIYLDLGITTMALEVLDRFLKALPKDMAGVKL
                     KVSALRKLNRPEEALAILDELVVNFPNDRDAHLQRKDILIKLERPGEAMQALLKALDS
                     DPLNEETYDLILEMTDDRPTWLGRKASALIHKDKAESALFELESALKLSPRDLTLMMI
                     KVEALENLGKQEEADDLLEEVLQRDPLNRAANLNMARRARTAGDGVKAIEHYKNVLRS
                     DPENITGWTEVAQLLMELGRYEESLRSYERLKEIMPDDIPALKGRMGVLAAMKDLAGL
                     DGAAQEMLGFAPEDVSAHLFIVDTFLSLDAEKEAEPYLEKAQSAFPKNLDVMDRRRSL
                     HSKHKKFQEVIAISEAQLAIRSDHLPAFRELGQAQMGLGNVVEAIKTFERGLKIWPED
                     VVMLESLRECFKRAARDKDVVEVSGRLLRVRPNDKSALFDKAVAVDRLGRKEEAIGLY
                     GQVLVIDHNDVDASIGISVALFSLEKYEEALARSAQGALHDPDKLVFWRIQADSLFML
                     KRFEEAVKAYDKAIALSPQEQKLLYQKGLCLESLRRFEEAIVCYDQAISLDAKDKNVW
                     ISKGIALEWLERHEEALACYDQALSLDKEGRFVHARRGQVLAKLSRHEDAVASFDKAL
                     EMGPKDIEVLTAKKNSLKTMGRYEDLVKVCDRIVKIEPKNKLAWVDRGMAQFRLGNFP
                     EAVRSYDRALEVEPGDMSVLQLKRSSVVAKGEASEILKVCEDILRIDPRNKTALMDKA
                     GSLEKLGRLEEALSTFNAAIMLDESDFQLHKGKGRVLTSLGKYGEAAEAYDRAFQLNH
                     DVDALSHKGRALLMMRNYDLALNVFDQCIAMDSTVPRYHSDRGRTLASLNRLDDAVAA
                     FEKALVLDRNDAQTWKYKGNALFRLGEMENAMVSLNRALELGADEFSIYKMRGRVMEE
                     LGRFEDAMDSYAKALLIEPNEPSVLEGMALIEDRLGNSAKALELLDRSLTADPRNRHG
                     WMERADIAEKLKRDEEVLKSYDNAIGLDPTDPAAWNGKGFALLRLGRYDQARRGFEKA
                     LELSPNMTSANEGLRMVDGKQRERQIGEMAGKVLEFQYRNGRKMSKEEVFREANVPYQ
                     MLDDVFSFLEQREYVDPAQLSEGEFASLEMQSRTALLMYYRSARSGQGGLTLSDVYSS
                     LPERDIAQAKRVLGYIEGVNDIDFTYVMPDKETEKLLRTALNMPEEKRNLFSFMEGLN
                     IGVYKARNILAIINSLRTGERPAPMPRSKGQRNPPAQRATDDLFVDQPRKKKPEKGPD
                     AMMLPDINETYERDGVRLFGQEERFLYDSLYPPKEKKPEKLDDMQGRKCLFHGALAVS
                     TCPKCSSMLCKECQTGGKCPRCGFMLGGKVKKQEEAAAPEEPSEPEERDWSRL"
     gene            complement(11888..13189)
                     /gene="truD"
                     /locus_tag="PKM11_05715"
     CDS             complement(11888..13189)
                     /gene="truD"
                     /locus_tag="PKM11_05715"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0031119 - tRNA pseudouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HNX48035.1"
                     /translation="MVQPSAQREREIGLEVFFSDTAGTGGKLKAQAEDFIVEEVSKYP
                     PEKPDSKICVVKVTATNWETNRLIRHMSKALGISRNRVGFAGTKDKRAVTSQLMSFEA
                     PVAEVMALHLSQVTVEGGYMAKRGMNIGDLVGNNFKIRVRDTVLKGEELRSSLQGTEA
                     SLKELNGFPNFFGVQRFGTVRPVTHLVGRAIVKGDLEQAVLLYIGNPSEEEDEPSRAA
                     REALQRDRDYAAALRDFPWKLTFERMVIGHLDRNPGDYAGAIGSLPTNLQMMFVHAYQ
                     SYIFNLILSERMSRGIPLNAPIVGDVVLPADKDGNPDHDKQVPVTKVNLDLVERQVRD
                     RRAFVSATLFGSESVFAEGEMGEIERAAIAKENLSPKDFLVPAIPHCSSRGSRRELIC
                     EYRDLKLDISEDEYTASFFLGKGCYATVLLRELMKSDISDY"
     gene            complement(13195..13470)
                     /locus_tag="PKM11_05720"
     CDS             complement(13195..13470)
                     /locus_tag="PKM11_05720"
                     /inference="COORDINATES: protein motif:HMM:NF025040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RpoL/Rpb11 RNA polymerase subunit family
                     protein"
                     /protein_id="HNX48036.1"
                     /translation="MEIELLEKEKDSIKVRIKGADMTLITPLVQGLLEEKDVAEVKYT
                     IGHAQMEDPTLFIRVKSGKPQAALKKTAKSLTNEFKEAREALQKDLK"
     gene            complement(13512..15272)
                     /locus_tag="PKM11_05725"
     CDS             complement(13512..15272)
                     /locus_tag="PKM11_05725"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA ligase"
                     /protein_id="HNX48037.1"
                     /translation="MLFRELADTYERLEATSSRLEMTDILAEAFRRFDPSDIKVAVYL
                     TQGQLYPDFNPLKLGMADKMILKAIAFASGAGESFVQDLMLKEGDPGIVAQKAFLNKK
                     QTTLFSSEPLTLKRAYETLEAIARSEGGGSQDMKIKLMAKLLGDASSSEAKFLSRVIT
                     GRMRLGVSSMTVLDALAVAFATKDDRDAVERAFNVSSDLGLVAEEMARHGLDGVKKIH
                     VQVNRPLRAMLAERMSSPEEILEKMGGTCAFEYKYDGVRIQAHICRGEVRLFSRKLDE
                     LTTQFPDVVVGLKRTIKADSAIIEGECVPVDQNTGEFLPFQEVSHRRGRKHGVDEAVE
                     DYPVKLCLFDCILKDGEDLTDRPFLQRREALLSIVEPDDSVTLSEIRVLSSADEAQAF
                     FQEAIKDGCEGLMAKSLADTSVYRAGNRGFLWIKYKKEYRSEMNDTVDLVVVGAFAGR
                     GKRKGFYGALLTATYDTAADRFQTVSKLGSGFDDANLAALLETLASDRIPEKHHLVDS
                     KMEADFWFQPRLVLEVRGAEITLSPIHTCSFGLIRPDSGLAIRFPRFTGRFRDDKEGR
                     DATTSQELLSMYQGQLKRVE"
     gene            complement(15306..16871)
                     /locus_tag="PKM11_05730"
     CDS             complement(15306..16871)
                     /locus_tag="PKM11_05730"
                     /inference="COORDINATES: protein motif:HMM:NF010337.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-related protein"
                     /protein_id="HNX48038.1"
                     /translation="MYFEHPLIKRQCVQRRDYQVDLAERASGSNTLLVLPTGLGKTVV
                     AAMVIARVLHSKGGKVLFLAPTRPLVEQHYRTMQNMIEGKRIGMMTGEVDPLQRELTY
                     LENDIVTSTPQVVSNDLKNGRLDLKDVKLIIFDEAHRSVGNYAYVAVAKAYQEYDGLV
                     LGMTASPGSDQAKIKEVVSNLNIKDIEVRTERDPDVAKYVQTIAMDWVEVELPPEMKA
                     LSRSIHLLYEQYIRELVALEVVDKDRVLNKRYLLEMAATWSARIQGGEKTRTLFNALS
                     AQARAVKVEHAIDLVETQGMSALRAYLQRIKDEASSDAGSKASRDIASSEHFQRICDE
                     AQAVKAEHPKMSRVMGVVARQLADHPDSRILVFTHYRDTCDLVANKLGKVENAKVAKL
                     VGQADSKGEKGLKQKEQVGVLQRFRDGEFNVLVATSVGEEGLDVASTDLVVFYEPVPS
                     EIRSIQRRGRTGRSRAGNVVIFITRGTKDEAYYYSSLNKERSMRRRLETMKEELSVGS
                     GTKKKPQKTLDGF"
     gene            complement(16923..17255)
                     /locus_tag="PKM11_05735"
     CDS             complement(16923..17255)
                     /locus_tag="PKM11_05735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly accessory protein"
                     /protein_id="HNX48039.1"
                     /translation="MVYMVTVTEEASKYIVDLIAKNEKSGFGIRIYLAGMGCSGAQFG
                     MSFQKDAKEGDIEQKADGFSVYYDEETKEVLDACTVDFVETPYGSGLVVNNPNASGGC
                     GSCGSGCH"
     gene            17472..17867
                     /locus_tag="PKM11_05740"
     CDS             17472..17867
                     /locus_tag="PKM11_05740"
                     /inference="COORDINATES: protein motif:HMM:NF025054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX48040.1"
                     /translation="MSRENMAAIIMESWGEEWKDEQLMDLLLDQMVDTTVLEGENGIE
                     AYYCVEDIDEYIFISSFQVRRNFQGKGLGTRMLDMIEEKARQDDKAEVELCVQSTNER
                     AKEFYYYHGYDLMYRNGNNLVMRKKLGRR"
     gene            17910..18368
                     /locus_tag="PKM11_05745"
     CDS             17910..18368
                     /locus_tag="PKM11_05745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HNX48041.1"
                     /translation="MSHRALIAAALVFIIAALCFAPSISATNAPSGLQATAGTGYIDL
                     SWQTVPGADYYYLYRGNGDGMTPVANLTAPITAYHDGDVDEGVNYLYYVTAWDNGTQS
                     APSNTISVTVLSEDEDSVILPVLAIVLSVIAIQVCVVMLLYFFKQKTQIK"
     gene            complement(18369..19337)
                     /locus_tag="PKM11_05750"
     CDS             complement(18369..19337)
                     /locus_tag="PKM11_05750"
                     /inference="COORDINATES: protein motif:HMM:NF014342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHHA1 domain-containing protein"
                     /protein_id="HNX48042.1"
                     /translation="MGNGSFSRDDRDKHIITRGNVDGIVSAAIFLNRFPTAKVTFVTS
                     PTAGAKVLSMDTFSDQIYLVDIAPVPDLVEAVRAKRLCQSLTLVDHHPSSLAVDCTTL
                     VKEGVSAANVLFHHLHPEVRLRKLVAVADLVEYMPTPLLDEEMRRFGRQRVDQESMVL
                     DFAWRLIIDDDRFRYITAKALSQGVWPSQVDSVRRRYTQVVNEKRWPRALAKVDSSIK
                     VRGPLGIMDDMDHNRTLYGFGTRALVEVAHRRGCDYAVMINPRGKYSSVSVRGIARDS
                     VDLGRFVADFTSENGVDGGGHPKAAGARIPTGSGELFLEHLLERVC"
     gene            19512..20237
                     /locus_tag="PKM11_05755"
     CDS             19512..20237
                     /locus_tag="PKM11_05755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48043.1"
                     /translation="MTDISYWGNSHMGGQESELQQCFARVGMEHGFTDVNANWERFKE
                     FKATWKRCSTSAELHITDYMKESGEPLITDLARGIFGRMGRGGVKEIYSERLKQHFLS
                     PEFILRNQPLYLRRSRNLAYAQMGRVHDLRALEQDLHDIGLVKRVPHAYMSWTKGDNR
                     QRVGYCSVIMRVVAISRVLDRKEIPSFVPSYVLYHELIHLENGLRFGSYHDREFRERE
                     RIHPHHEEAERWLRRVVSDPQFR"
     gene            20288..21256
                     /locus_tag="PKM11_05760"
     CDS             20288..21256
                     /locus_tag="PKM11_05760"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HNX48044.1"
                     /translation="MRKTIKINELKAGGTVDDLFAVRFKKPVMPYKNGFTFQMWVSDA
                     GGDIAVKYWGEKDEKLVKALSDAISKGAVVRVNGKVTEYNGALEIHVNPSSGDSVAVL
                     KEGEFEVADFVASTTEDVEQMRAQLFVIMRKIKDVHLKQLLESFFADEEFVKEFCFCP
                     AAITHHSNYIGGLLEHTLRVVRTCEHYAQQYPDLDRDLLVTGAILHDVGKLREYTVSS
                     IIGSTDAGRLVGHLVIGAGMVNDACRLLGDFPPELNLKVQHLVLSSHGTKEFGSPKEP
                     LFPEALALAMADLSTTRIEDMLLVKKTANTEDDWVQDKNVGSVYLR"
     gene            21492..>22502
                     /locus_tag="PKM11_05765"
     CDS             21492..>22502
                     /locus_tag="PKM11_05765"
                     /inference="COORDINATES: protein motif:HMM:TIGR01494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HNX48045.1"
                     /translation="MTKEFSWHDIEISEAFDRLGSSPDGLSETEATARLREHGPNELD
                     QTGGINAWHMLLEQLRNPLNFVLVAAALISFFAGKTLDTVVIAIIIIFNTAMGFVQEF
                     RAEKALQALRSMVTPEAEVLRPCEGAKGACEEIRVKAEHLVPGDVLLLEAGDKVPADA
                     RLFEAANLEVDESMLTGESLTVRKGVEVMPAGSGVADRKNLVYSGTIVTQGRARAVVY
                     STGMRTEIGKIAQLIGSTERAETPIQRRTKDLSKKLGAFALFTSIITLTVGFFKGFEF
                     TEMLLFALASAVSAIPEGLLVVLTITLAIGGHRMVRRNALIRKLQAVETLGSVTTICT
                     DKT"
BASE COUNT         4687 a         6465 c         6706 g         4544 t
ORIGIN      
        1 cccacccctt tagcggatga tattcatata tgtggataaa tattttcccc atgtctggat
       61 ggacttttcc gtttaatact ggtccgcgaa agacagagat catctctccg gcaccagtat
      121 ctcgaacagc gtctgcgcca actccttcgc tttcgcctta tcgttcaaag gatgcaccag
      181 cactcttccg ctgccgtaga tggtgacgtc catctgtccg accttggtga tcaggaagag
      241 ctcctgtgct tccacctcgt atcctttcgc ccgcaaggca tcgcccgaaa gcattaggtc
      301 gaaccgtaca tggtctaaag ggatggccga catcgaatcg ctgcggcata ttcgttcgac
      361 acggaacttc atcccttcag ctccctcaga acgacaaagg catccgcccg gaagcgttcc
      421 aacgtgctct cgttgacgat gagcgcatca gccagtgcta tcgtctcccc caatccccag
      481 ctcagttccc gcttgtcccg ctcgtcgaac tcctggcggt cgcgaggggc gtcggaacgt
      541 cccctgctta cgagacgagg aaatctggtg gatggagaac tgtgcaccgc catgaccttt
      601 acgtgcgttc cgaacgcctc acggaaaacg ctcacctcgg acatgccccg gcagccgtct
      661 atgagagtgt cgccttcgcc gaccaatggg acgatgcgct tggcccagat gtcgtaaccg
      721 tggcgctgcc gttcctcgtg cgcgaacttg ccgacctcct gcggcgggat gccgttcctc
      781 aacgcttccg cccggaccac gtcccccatc cggcggacct ggtatcccag ttcgagcgcc
      841 acggacacca gttcctcctt gcccgccccg ggcattccgg tcaggatgag aacgcccatc
      901 tcgctcacct tgaaaaaagt aagaacggga cctgcctcac agcaggttcc cggctatgtc
      961 gtccagctgg cggtcgcagt acacgcagcg cagcatcggc gggttcttgg attccaccac
     1021 gaactccggt tcgatcggct cgttctggtt ggtgatgcag ttgggattgc tgcatttggc
     1081 cttgccgacc actcgctcgg gcatcttgac gctgtacttt tcggcgacat tgaaatcgcg
     1141 gatgatgttg atggtggcct tcggagctat aagcgcgatc ttgtccactt ccctggggtc
     1201 cagctcgcgg tcctccacct tcaccacgtc cttccatccc tccttcttcg aagggacgtg
     1261 cattagaacg ctaaccggtg attgcacctt gccgccatcg gtcatgccta tgatcctcaa
     1321 gaccttcagg gccatgccgc agtcgatgtg gtcgatgacc gtgccgttgc gtatcggggt
     1381 caccttgaac tccttcatca cagctcacct cccaggacca ggttcaggag cgccattcga
     1441 accggcactc cgttgaacgc ctgctcgaaa tacttggcgt gtggcgtacc gtccacctcc
     1501 gggtctatct cgtccactct gggcaagggg tgcatgacga tcaggtcgct cttcgcttcc
     1561 cgtaaaagct tcttgtccac ccggtacatc ccggccacct tctggtactc ggccaggtcg
     1621 gggaaacgct ccttctgtat tcgggtgacg taaagaacgt cagcctcagc gatggtctcc
     1681 tccaggcggc tggtcagctt cggctttccg cccgctttct ctacctgctt gaccgtttct
     1741 ttgggcatct gcaatgccgc aggcgccacg aacgtaagat cgacaccgaa ggagctcagc
     1801 gcctcggcca tggaatgcac cgttcgcccg tacttcaggt ctccgaccat gaccaccttc
     1861 agcttgctga agtccttctt gatgcgcttg atggtgaaca ggtccagcag cgtctgcgtg
     1921 ggatgctgtc cagccccgtc gccggcgttg atgaccggtt tggatgagaa tctggcggcc
     1981 aatctggccg acccctctcg cgggtggcgg atgactatga tgtccgaata cacctcgacc
     2041 atgcgtatgg tgtccgccaa cgattcgccc ttggatatcg agctcatgga cggcacgccc
     2101 aggtcggtta tccggccgcc gaggcgcatc atggcgctct cgaaggacat ccgggtccgg
     2161 gtggacggct cgaagaaaag cgtggccagg atcttcccgt ccaatgcctt ggagctcatt
     2221 tccccccgag catacggtat cattctctcg gaacgttcca aaacctgctc gatctgctct
     2281 ctcgtcagat cgcggatcga cacgatgtcc attccttcga aggtcatgct ctcagtgtcg
     2341 aatcctcaag accgtatttg actcttggca tggcgtaggc atcggccgcc tgaacacagg
     2401 gcatgaacgc cgcataaaag aacgataagg gctcaatcgg cgtcagacga ttcgaacttc
     2461 tgcagggcgc cctgcatctt cttgtaccag ttctccacgc agctctcgag cttctcccga
     2521 agttccttgc ggcttatggc ccggtacacg tggaaatacc cgccgcgggg tatgctgcgc
     2581 gtctcccgca ggaccatacc gcaggtcatc atcttctgca atgcgcgata aacagttgaa
     2641 cggtccttgc ccatcaggtc cgccagctcg ttggcgttca ccggtccggt ctccaacagc
     2701 ctctcgtaga cctcgacctc gaaaccgttc aggctgtagg cgcactggac caggtcttgg
     2761 cagctgttga cgtccttgat ggactccggc atcatatccc gttccttctc tgagtaaagc
     2821 ttataaacta acagttatat ataattgttg cacaaccgtg caaaaccgct atatggtgat
     2881 cataatggac aagaaggaaa cgcttgatgc caagggcctg atgtgcccga tgcctatcgt
     2941 gaagctggcc aagaagatga aggaaatgaa ggtcggagag gtcctcgagc ttatcgcgga
     3001 cgacgtgggc tccaaggagg acgtaccggc ctggtgcaag aggaccggca acgaactggt
     3061 cagccagaag gaagagggcg gagctttctt cttctacatc aagaaggtcc agtaagataa
     3121 ttacgttatt gaggtgacaa aaatggcaga gactaagaag ttcgcaatgg tggtggcaga
     3181 gggcaccttt gacaaggcca tgatggccat gatgatgggc aacactgccg ccagcatggg
     3241 gatcgagacg catatattct acaccttctt cgggctgaac ctgttgaaga agggagccaa
     3301 gccgaagatg ccgggcatga tgcgcttctt caccggaatg atgatcaaga agatgaaagg
     3361 catcgggctt gatggctacc aggagcagct ggagatggcc aaggagctgg ggatcaagat
     3421 ctacgcctgc agcacctcca tggagctaat gggcatcaag aaggaagatc tgatcgatgg
     3481 cgtgaccgta ctgggcgccg cggccttcct ggacatcgga actgacgctg acatgcagct
     3541 gttcatcggc tgatggtgat ctgatgaagt ccaagctgtt cataacgctg aaatcgccgc
     3601 acgagttcgg cggattggag cttgtccgtt cgtcggccaa gggcgccaag agcgccttgc
     3661 tcctgttcga ggacgcggtc atcttcgccg ccaacgccaa gatgggcaag gagctacttt
     3721 ccgcggtcca ggacgtctac gtgatgaagg acgactggga ggcccgcgga ttgccgttgg
     3781 ccgtcccggg gttcaagatc gtggactacc cggaagcggt cgagctgatc atggaaaggt
     3841 acgagcagac catcacggtg tgaggtgaca agatgaagac tatggttatc cagataagga
     3901 gcggtaccat gatgaacatg gacaccaaca tcgcagtcaa gctcgcccag gccgccttgg
     3961 acaaaggtta caacgtccga atgttcggtt acggcgaggc ggtgacgatc atcaagaacg
     4021 ggcaggaccc caagcgcttc cccaacgtgg gcaaggagac caaggagctg ctcggcaagg
     4081 gattggaggt cgtcgtctgc gagacctgct gcaaggcgcg gggaatattg agaggagagg
     4141 agatcgaagg caccaagatc ggcagcctga ccaacgacct gtccaggttc gtggccgagg
     4201 gcgatcgcat ggtgaccatc gcgaggtgat tcaaatggct caaagcttgc tgatattggt
     4261 taccaaggct ccgtacggtt tcgaggaggc cttcgccgga cttcgtgccg gactgggaat
     4321 gttggcatcc ggacaggtcc cggtctcgaa cgccttgctg gtgggcgagg gaacgctcaa
     4381 cgcggtcgcg gcgcaaaagc cggaagcggt gcgcatgcct tccaacgcgg aagcgatcaa
     4441 cgacctcctg gagttcgagg ccaaggttta cgtggtcaag gaggacctac tgcacctggt
     4501 cggagacgtc ccgctcctgg aaggggtgga gctgatcgac tgggaaagag cgcgtcaggt
     4561 catcgacgag cacgacatgg tcaccacctt ctaaaccact tttcaaaccc cttctgacca
     4621 ttctttttta atagggatgc taataaccgt tcatgttgga actgctggcc aggtcgggga
     4681 ccgcccgccg ctgcctgtgg tccctggaag gggccaaggt cgagactccc ggagcgttcg
     4741 tcgtggaagg gggagcggag ggtctcgctt tggaactggc cgacggttcg tccgttctgc
     4801 agatgaacgg gcgcacggta ctggagatga ccgggaacgg gctgctcgca ccgctcaagg
     4861 cccgcggcgg aatgaaggat agctgccttc cgcccgtgtc cgatgcgcag gagatcgccg
     4921 ttctcgacgg cgcgttcgag ctgcgacgtg acgcccgggc gttcgtcagg gcgctcgtgg
     4981 agctccgaac gtccgtgggc cgttccaagc tgatctacgc ccccggcatc gccgagacgt
     5041 ctaacctagc catcctttcc tatctgggag tggacctctt cgatacgtcg ctgatcgatc
     5101 accgggcggc catcggggag ctgtcgctgg tcgaagggcc tatgctcgct tcgaaggccg
     5161 attgggtccc ggaaggttcc gaccttcggg cgatgaacag ggagaacatg ttccgagagc
     5221 tggccctggt gcgcggcatg atctcctccg ggcgcatgag ggagttcgcc gaaatgcgct
     5281 gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn natggcctcg cagggctatg
     5401 accacgtcat cctgcacctg ggggacgagg ggccgatcat ccaggaggtc ctggacggaa
     5461 cgattacttc caacggatcg ccgacgtcca acgaatccct gggcatgctg aaggaaaccc
     5521 tcactgaact gtgttccaga tatgaccgcg tggacccctc caaggaccgc tgggcggcga
     5581 tgtcgtccgt ggccggcttc cagttcggtc ccggcggcga ggcacttctt gatgaggcgt
     5641 acatactcgg caactatccg ttcatgaaga tcatggccca caaggagcag ctgggcatgc
     5701 tgaaccccga gcgggggatg atatccttga ccgtagaagg ggcggaggcg atattgccgc
     5761 tcattccgaa ggtcaccatg ggcgacttcg agctcaaggg aagtctcttc gccgtcggcg
     5821 tgagcgatgc tgattcctcc atacgagccg gggaggaagt ggccatcatg cgcaacggca
     5881 agatcgtcgg ggtgggagtg gcttccatgg gcgggcggga gatggtggag atgcgccgtg
     5941 gcgaggcggt caaggtaagg cacaagcgca agtgaggtca ctttcgccgc tcatttttct
     6001 atccagcatt gacgagcggt gttcgacatt cggtcacccc tccccttcct ggctttaata
     6061 ccggcaggac gtaccatgtc ttgcaggcaa gaacgcctat cacgatgaat accatcctaa
     6121 ggtgcgggag gaggattagg ccccgcttcc ccgccttacc tttttttacc gatgcgatag
     6181 taattctttg gttagatacg gtcaaaaaga gggcgcgagc cggaattttc gttctccgtc
     6241 ctagttttcg cccctctttc ttcaacaatt tctttataaa ccgtccatta ttgcttatat
     6301 aacccttgga ttacagaact agaggcgatt accatttcga actactcaat acaaaacgtc
     6361 gtggcttctg ccaacctggg cactgaactc gacctcaccg agctcgctct caatctgaac
     6421 ggcgccgaat acgagccaga gaccttccct ggcctgatat tccggttgaa ggagccgaag
     6481 accgctaccc ttctgttccg cagcggtaag ctggtctgca ccggggcgac caacctggag
     6541 gatgtcaaga aggccgtgaa gaccgttgtg gccagcataa ggaaggctgg cgtcaaggtc
     6601 gaggcggtcc cgccggtaac ggtgcagaac atcgtcgcct ccgcggacct gggacagccg
     6661 gtcaacctat cctcggtcgt gatcaccttg ggtctggacc gtgtggagta cgaaccggaa
     6721 gtgttccccg ggctggtgta caggctcacc gagcccaagg tagtgatcct gctcttcggg
     6781 tccggcaagc tggtctgcac cggtgccaag gtcccggagg acgtcgaggc cgcggtcacc
     6841 aagatcaaga acgagctgcg cgccgagaac ctgttgctct aagggcggca gtgaaacgca
     6901 gacctgaaat ggtctgccaa aatctttctt tttttaatct ctgataaaag gaaaagaagt
     6961 gcaggtgtcg ggattcgaac ccgagtgttt agcttggaag gctaaaatcc tgaccgctag
     7021 attacacctg cgcggtgccg tcataatagg aattccatat tttaaccctt ccataatgta
     7081 aaaatcgctg gcgtccgggt tgataagaaa aaaggtagag gctagtggaa agtgtaaggg
     7141 ggggactctc cactagagtc gttccaggaa cgtatgaacc tacaggctca tgatcttcag
     7201 gtcattgatg aggtcccaca gttccatggt ctcctgtccc tgctggtcca attcaaaggc
     7261 catcagcttc aggtcctgga tggtgtgggt cttcatccac tcaacagcat gaccatcgta
     7321 catctgttcc gagaacgaac cctcgtttcg cctcattttt gcatcccatc tgtccgacct
     7381 atgtcagaca aataatgcta ttgtgtcaca gggtatttat aacttatctt ttctatatcc
     7441 agcacaggat cgtaccattg gtcggacgca ttttttctaa aagtacaatg gtcagacaaa
     7501 aaggatataa acgtatgaca atatgaaaaa cgaagggctc gacaaacata ttaatcgtct
     7561 gggcttcatt caagtcagga taggtgcgga gatgggtctg ttcaataact tgttggatgc
     7621 ggaggcgagg gccgtaaaga aggccgtgag atcattagac gtggccgaca agcatatgca
     7681 ggcgaaggaa acggacaagg cattggtgga ggctgacaag gcccgagtgg cgttggaagg
     7741 cctggacccc aaggccgtcg tcaacctgaa cgattaccgc accgcgatat cccgcatatc
     7801 caacatctac ctggacctgg gcatcaccac catggccctg gaggtcctgg accgcttctt
     7861 gaaggccttg cccaaggaca tggccggggt caagctcaag gtatcagcgt tacggaagct
     7921 gaaccgaccc gaagaagcgt tggccatcct ggacgaactg gtggtcaact tccccaatga
     7981 ccgagacgcc cacttgcagc ggaaggacat actaatcaag ctggagcgtc caggggaggc
     8041 catgcaggca ctgctcaagg cattggactc cgatcctctg aacgaggaaa cctacgatct
     8101 gatactggag atgacggacg accggccgac atggttaggg agaaaggcct ccgccctcat
     8161 ccacaaggac aaggcggaat ccgcgctctt tgaactggag agcgccctga agctatcgcc
     8221 cagggacctc acgctcatga tgatcaaggt ggaggccctg gagaacctcg ggaagcagga
     8281 ggaggcggac gaccttctgg aggaggttct gcaacgggac cccctgaacc gggcggccaa
     8341 cctgaacatg gcccgcaggg ctcgtaccgc tggcgatggc gtcaaggcca tcgaacatta
     8401 caagaacgtt ctgcgttcgg accccgagaa catcaccggc tggaccgagg tcgcccagct
     8461 gctcatggag ctgggacgtt acgaggaaag ccttcgctct tacgaaaggc tcaaggagat
     8521 catgccggac gacatcccgg ccctgaaggg aagaatgggg gttctggcgg ccatgaagga
     8581 cctggccggc ctggatgggg cggcacagga gatgctgggc ttcgctcccg aagatgtgtc
     8641 cgctcacctt ttcatcgtcg ataccttcct atcgctggac gccgagaagg aggccgagcc
     8701 gtatttggaa aaggcgcaat cggccttccc gaagaacctg gacgtgatgg accgccggcg
     8761 gtccctgcat tctaaacaca agaagttcca ggaggtcatc gccatcagcg aggcgcagct
     8821 ggcgatcagg tcggaccacc ttccggcctt ccgggaactt gggcaggctc agatggggct
     8881 cggcaacgtc gtggaggcca tcaagacctt cgagcgcggg ctgaagatat ggcctgagga
     8941 cgtcgttatg ctggaatcgc tgcgcgaatg tttcaaacgc gccgcccggg acaaggacgt
     9001 ggtcgaggtg agcggtcgtc tgttgcgggt caggccgaac gacaagtccg cccttttcga
     9061 taaagcggtc gcggtagacc gtctaggacg aaaggaggag gccataggtc tttacggtca
     9121 agttctggtc atcgaccata acgatgtgga cgcctccata ggtatttccg tggccttgtt
     9181 ctcattggag aagtacgagg aggccttggc cagatcggcc cagggagcct tgcacgatcc
     9241 cgacaagctg gtgttctggc gcatacaggc cgattcgctg ttcatgctga agcgcttcga
     9301 ggaagcggtg aaggcgtacg acaaggcgat cgcgttatcg ccgcaggaac agaagctgct
     9361 ctatcagaag gggctgtgcc tggagagcct ccggcgcttc gaggaggcca tcgtctgcta
     9421 cgatcaggcc atatctctgg acgccaagga caagaacgtc tggatatcca aggggatcgc
     9481 cctggaatgg ctggagaggc acgaggaggc cctggcctgc tacgaccagg cgctctctct
     9541 agataaggag gggcgcttcg tgcacgcccg gcgcggccag gtcctggcca aactttcgcg
     9601 gcacgaggat gcggtggcgt cgttcgacaa ggcgctggag atgggtccca aggacatcga
     9661 ggtgctaacc gccaagaaga acagcctgaa gaccatgggt cgttacgagg acctggtcaa
     9721 ggtatgcgac cgaatagtca agatcgagcc gaagaacaag ctcgcctggg tggacagggg
     9781 aatggcccag ttccgcctcg gtaacttccc ggaggccgtg cgttcgtatg accgggcttt
     9841 agaggtcgag ccgggggaca tgagcgttct gcagctcaag aggtcgtccg tggtggccaa
     9901 gggcgaggcc agcgagatcc tgaaggtctg tgaggatatc ctacgcatcg atccgcgcaa
     9961 taagaccgcc ctaatggaca aggcagggtc cttggagaag ctgggacgct tggaggaggc
    10021 gctgtccacc ttcaacgccg ccatcatgct ggatgaatcg gacttccagc tgcacaaggg
    10081 gaaggggagg gtgctgacct ccctgggcaa gtacggagag gcggccgagg cttacgatag
    10141 ggccttccag ctgaatcatg acgtggacgc tctatcgcac aagggccggg ctctgctgat
    10201 gatgcggaac tacgatctgg cgctgaacgt tttcgatcaa tgcatagcaa tggacagcac
    10261 cgtgccccgt tatcacagcg atcggggacg aaccttggcg tccctgaacc gtctggatga
    10321 tgcggtggcg gccttcgaaa aagccctggt tctcgatcgc aacgacgccc agacctggaa
    10381 atacaagggg aacgccctgt tccgcctggg ggagatggag aacgccatgg tcagcctcaa
    10441 ccgggccttg gagcttggcg cggacgagtt ctcgatatac aagatgcgcg gccgggtgat
    10501 ggaagagctg ggtcgatttg aggatgccat ggactcctac gccaaggcgc tgctcatcga
    10561 gcccaacgag ccttcggtgc tggaagggat ggcgctcatc gaggaccggc tgggaaattc
    10621 cgcgaaggcc ctagagctgc tcgatcgctc gctgacggcc gatccccgta accgtcacgg
    10681 ttggatggag cgggcggaca tcgccgagaa gctgaagcgc gacgaagagg tgctgaagag
    10741 ctatgataac gccatcggac tcgatccaac cgacccggcg gcctggaacg ggaagggttt
    10801 cgcactgttg cgactgggaa gatacgacca ggcccgccgt ggtttcgaga aggccctgga
    10861 gctcagcccg aacatgacct cggccaacga agggctgcgc atggtggacg gcaagcagcg
    10921 cgagagacag ataggggaga tggccggcaa ggtcctggag ttccagtacc gcaacggaag
    10981 gaagatgagc aaggaggagg tgttccggga ggcgaacgtt ccgtaccaga tgctggatga
    11041 cgtcttcagc ttccttgagc aacgcgagta cgtggacccg gcgcagcttt ccgaggggga
    11101 gttcgcctcc ctggagatgc agtcccgcac cgcactgctg atgtactacc gttccgccag
    11161 gagcggacag ggtgggctta ccctgtcgga tgtttattcc tcgctaccgg agagggacat
    11221 cgcccaggcc aaacgcgtac tcggctacat cgagggcgtt aacgacatcg acttcaccta
    11281 cgtgatgcct gacaaggaaa ctgaaaagtt gctgcgaacg gcgctcaaca tgccggagga
    11341 gaagcgcaac ctgttctcgt tcatggaagg gctcaacatc ggcgtctaca aggcgcgcaa
    11401 catcctggcg atcatcaatt cgctgaggac cggcgaacgt ccggcgccca tgccccgctc
    11461 caagggtcag cgcaatcccc cggcgcagcg ggccaccgac gatctgttcg tcgatcaacc
    11521 gcgcaagaag aagccggaga agggtccgga cgcgatgatg ctccccgaca tcaatgaaac
    11581 ttatgagcgc gacggggtgc gtctcttcgg ccaggaggaa cgattcctct acgattccct
    11641 gtatcctcca aaggagaaga agcccgagaa gctggacgac atgcaggggc ggaaatgcct
    11701 gttccacggc gctctggcag tatcaacatg tccgaaatgc agcagcatgc tgtgcaagga
    11761 gtgccagacc ggcggaaaat gccctcgttg tggcttcatg ctcggaggga aggtgaaaaa
    11821 gcaggaggaa gcggcggcgc cggaggagcc ttccgaaccg gaggaacgcg actggagcag
    11881 gctgtgatca atagtcggag atatccgact tcataagctc ccggaggagc accgtggcgt
    11941 agcagccctt gcccaggaag aaggaggcgg tgtactcgtc ctccgagata tccagcttga
    12001 ggtcgcggta ctcgcagatc agctccctac gggaaccgcg cgaggaacag tgcgggatgg
    12061 ccggcaccag gaagtccttg ggcgacaggt tctccttggc gatcgccgcg cgctcgatct
    12121 cgcccatctc cccttccgcg aacaccgact cggagccgaa gagcgtggcg gatacgaacg
    12181 ctcgtcggtc ccgcacctga cgctccacca ggtccaagtt cactttggta actggcacct
    12241 gcttgtcgtg atcgggattt ccatccttgt ccgccggcag aaccacgtct ccgacgatgg
    12301 gggcgttcag tggtatcccg cggctcatgc gttccgacaa aatcagattg aagatatagg
    12361 actggtaggc gtgcacgaac atcatctgca agttcgtcgg gagagagccg atggctccgg
    12421 cgtaatcgcc cgggttgcgg tccagatgcc cgatgaccat cctctcgaag gtcagcttcc
    12481 aggggaagtc gcgaagggcc gccgcgtaat cccggtcccg ctgcagggcc tctcgggccg
    12541 cccgggacgg ctcgtcctcc tcctcgctcg gattgccgat gtagagaaga acggcctgtt
    12601 ccaggtcgcc cttgactatg gcccggccga ccagatgggt caccggacga acggtaccga
    12661 agcgctgcac gccgaagaag ttcgggaagc cgttcagttc cttcagggac gcttcggtgc
    12721 cttgcagcga ggaacgaagt tcttcgccct tgaggacggt gtcccggacc cgtatcttga
    12781 agttgttacc gaccagatct ccgatgttca ttccgcgctt ggccatgtat cccccttcca
    12841 cggtgacctg ggagaggtgt aaggccatga cctcggccac cggggcctcg aaggacatca
    12901 gctggctggt taccgcgcgc ttatccttgg tcccggcgaa gcccacccgg ttgcgggaaa
    12961 ttcccagggc ctttgacata tggcggatga gacggttggt ctcccagttg gtggcggtga
    13021 ccttgaccac gcagatcttg ctgtcaggct tctccggcgg gtacttggac acctcttcca
    13081 cgatgaagtc ctccgcctgg gccttgagct tgccgccggt gccggcggta tcggaaaaaa
    13141 agacctccag ccctatctcc cgttcacgtt gagcgctggg ctgtaccatg aaaattactt
    13201 caggtccttc tgcaaagctt ccctggcctc tttgaactcg ttggtgaggg actttgccgt
    13261 cttcttcaag gccgcctgtg gcttgccgga cttgacccgg atgaagaggg tagggtcctc
    13321 catctgggcg tgcccgatgg tgtacttaac ctcggctaca tccttctcct caagcaaacc
    13381 ctgcaccagg ggggtgatca gcgtcatgtc cgctcccttg atgcggacct tgatggagtc
    13441 cttttccttc tctaagagct cgatctccat gaattggacc aatatgggag ggggctataa
    13501 accttttgac atcactcgac ccgcttgagc tgtccctggt acatggagag cagttcctgg
    13561 ctggtggtgg catcccgtcc ttccttgtcg tcccggaaac gcccggtgaa cctcgggaat
    13621 cgtatggcca gaccggagtc cggacgtatc agtccgaagg agcaggtgtg tatcggggag
    13681 agggtgatct ccgctccccg cacctccagc acgagccggg gctggaacca gaagtccgcc
    13741 tccatcttgg aatccaccag gtgatgcttc tccggtatcc ggtcggaagc gagcgtctcc
    13801 aatagcgcgg caaggttggc gtcatcgaaa ccggagccca gcttggagac ggtctggaac
    13861 cggtcggccg cggtatcgta ggtcgccgtg agcaacgccc cgtagaaccc cttgcgcttt
    13921 ccgcgcccgg cgaaggcgcc aacgaccacc aggtccacgg tgtcgttcat ctcggagcgg
    13981 tactccttct tgtacttgat ccacaggaac ccgcggttcc cggcgcgata gacggacgta
    14041 tcggccagcg atttggccat caatccctcg cagccgtcct tgatggcctc ctgaaagaac
    14101 gcctgcgcct cgtcggcgga tgacagaacc cggatctccg agagggtgac cgaatcgtcc
    14161 ggctccacga tcgagagcag cgcttcgcgg cgctgcagga acgggcggtc agtgaggtcc
    14221 tcgccatcct tcagtatgca atcgaaaagg cagagcttga ctgggtagtc ctccaccgcc
    14281 tcgtccaccc cgtgcttgcg accgcggcgg tgggagacct cctggaacgg aaggaactca
    14341 ccggtgttct ggtccaccgg aacgcattcc ccctcgatta tggcgctatc ggccttgatg
    14401 gtccgtttaa ggccgaccac cacgtccggg aactgcgtcg taagctcgtc cagcttgcgc
    14461 gagaacagtc tgacctcgcc ccggcatatg tgcgcctgga tccgtacgcc gtcgtacttg
    14521 tactcgaagg cgcaggtccc gcccatcttc tccaatatct cctcaggaga ggacatccgc
    14581 tcggccagca tcgcccgtag aggtcggttc acctgcacat ggatcttctt gaccccatcc
    14641 aacccgtgcc gcgccatctc ctcggccacc aatcctaggt cggatgatac gttgaaggct
    14701 cgttccacag cgtccctatc gtccttggtg gcgaaagcga ccgccaaagc gtccagtacg
    14761 gtcatggacg agacgcccaa acgcatgcgt ccggtgatga cccgggagag gaacttggcc
    14821 tcggacgacg aggcgtcgcc caacagcttg gccatcagtt tgatcttcat gtcctgggag
    14881 ccgcccccct ccgaacgggc tatcgcttcc aaggtctcgt acgccctctt caacgtcaga
    14941 ggctcggagg agaacagggt ggtctgcttc ttgttcaaga acgccttctg cgccacaatg
    15001 cccgggtcgc cctccttgag catcaggtcc tggacgaagg attcgccggc accggaagcg
    15061 aaggcgatgg ccttgaggat catcttgtcc gccattccca gcttcagtgg gttgaagtcg
    15121 gggtagagct gtccttgggt gaggtagacc gcgaccttga tatcggaggg atcgaagcgg
    15181 cggaacgctt ccgccaatat gtcggtcatc tccagcctgg aggaggtggc ctccaacctc
    15241 tcgtaggtgt cggccagttc ccggaacagc atgctaatgc gaacggtttg cgattattta
    15301 actgctcaga acccgtccag ggtcttctgg ggcttcttct tggttcccga accgacggac
    15361 agctcttcct tcatcgtttc cagccggcgg cgcatggacc tctccttgtt cagcgacgag
    15421 tagtagtacg cctcgtcctt ggtcccccgg gtgatgaata tgaccacgtt cccggcccgc
    15481 gagcgtccgg tacgcccgcg cctctgtatg ctgcggatct cggacggtac cggttcgtaa
    15541 aacaccacca ggtcggtgct cgccacgtcc aaaccttcct cgcccaccga ggtcgccaca
    15601 agaacgttga actccccgtc ccggaagcgc tgcagcactc cgacctgctc cttctgcttc
    15661 agtcccttct cgcccttgct gtccgcctgg ccgaccagct tggcgacctt ggcgttctcc
    15721 accttcccga gcttattggc caccagatca caggtgtccc ggtaatgggt gaagaccagt
    15781 atgcgcgagt cgggatggtc cgcgagctgc ctggccacca ctcccatcac ccgggacatc
    15841 ttggggtgct cggccttcac cgcctgggcc tcgtcgcaga tcctctggaa atgttccgag
    15901 gacgctatgt cccgggaggc cttcgaaccg gcgtccgagg acgcctcgtc cttgatgcgc
    15961 tgcaggtacg cgcgcagggc ggacatcccc tgggtctcca ccaggtcgat ggcgtgctcc
    16021 accttcaccg ccctggcctg agcgctcagg gcgttgaaca gggtccgggt cttctcccct
    16081 ccctggatgc gggcgctcca ggtggcggcc atctcgagca gatagcgctt gttcaggacg
    16141 cggtccttgt ccaccacctc cagggccacc agctcccgga tgtactgctc gtagagcagg
    16201 tgaatggagc gggatagagc cttcatctct ggcggcagct ccacttccac ccagtccatg
    16261 gcgatcgttt ggacgtactt ggccacgtcc gggtcccgtt cggtgcggac ctcgatgtcc
    16321 ttgatgttga ggttcgagac cacctccttg atcttggcct ggtcgctgcc cggggaggcg
    16381 gtcattccta gaacgagacc gtcgtattcc tgataggcct tggccacggc gacgtaagcg
    16441 tagttgccca cggagcggtg ggcctcgtcg aagattatga gcttgacgtc cttgaggtcc
    16501 agtcggccgt tcttcaggtc gttggagaca acctgcggcg tggaggtgac tatgtcgttc
    16561 tccagatagg tcagctccct ttgcagggga tccacctcgc cggtcatcat gccgatgcgc
    16621 ttcccctcga tcatgttctg catcgttctg taatgctgct ccaccagcgg tctcgtgggc
    16681 gccaggaaca gcacctttcc gcccttggaa tggagcaccc gggcgatgac catggcggcc
    16741 accacggtct ttcccaggcc ggtcgggagc accaggagcg tgttggagcc agaggcgcgt
    16801 tcggccaggt ccacctggta gtcgcgccgc tgcacgcact gccgcttgat cagggggtgc
    16861 tcaaaataca cgatgggtaa tcgttatggg aataataaaa gaaaagggat tggggaaggg
    16921 atttagtggc agccgctgcc gcaggacccg catccgccgg aggcgttggg gttgttgacg
    16981 accaggccgg aaccgtaggg ggtctccacg aagtcaacgg tgcaggcgtc caggacctcc
    17041 ttggtctcct cgtcgtagta gacggagaaa ccgtccgcct tctgctcgat gtctccttcc
    17101 ttggcgtcct tctggaagga catgccgaac tgggcgccag agcatcccat tccggccagg
    17161 tagatcctga tgccgaaacc ggacttttcg ttcttggcga tcaggtccac gatgtacttg
    17221 ctagcttcct cggtaacagt gaccatgtat accattctcc tgagggtttc aaatcaacat
    17281 cacctattta aacagtcgta tagatgcctc gcgctggaac atggtatcaa ggcgcatggc
    17341 caaacttatg gtcatgggag cttcgctcac cgatggcgaa tgttcacgtc atcctttttc
    17401 taatggttcg ctatacacaa ccgatgcgct gtcgttccat gcaaaggtcc gatcttcccg
    17461 agctggtttc aatgagccgg gagaacatgg ccgccatcat catggagtcc tggggggagg
    17521 agtggaagga cgagcagctg atggaccttc tcctggacca gatggtggac accaccgtgc
    17581 tggaagggga gaacggcatc gaggcctatt actgtgtcga ggatatcgac gagtacatct
    17641 tcatatcctc cttccaggtc cggcgcaact ttcagggaaa ggggttggga actcggatgt
    17701 tggacatgat cgaggaaaag gcccgccagg atgacaaggc cgaggtggag ctgtgcgtcc
    17761 aatccacgaa cgaacgcgcg aaggagttct attattacca cggctacgac ctgatgtacc
    17821 gaaacggtaa caacctggtg atgcgcaaga agctgggccg aagataactt tttaatcgtt
    17881 ccgccctcat catccgacgg gagtaaaaaa tgtcacaccg cgccctcatc gcagcggcac
    17941 tcgtattcat catagcagcc ctgtgcttcg ccccctcgat atccgccacg aacgctcctt
    18001 cgggactgca ggccacggcc ggaacaggct atatcgacct gagctggcag acggtcccgg
    18061 gcgctgatta ttactatttg tatcgcggca acggggacgg tatgacgccg gtggccaacc
    18121 tcaccgcgcc gatcaccgcc tatcatgatg gggatgtgga cgagggcgtc aactacctct
    18181 attacgtgac ggcctgggac aacggcaccc agagcgctcc cagcaacacg atatccgtga
    18241 ccgtgctctc ggaggatgag gatagcgtga tcctgcccgt gctggcgata gttctgtcag
    18301 tgatcgccat ccaggtctgc gtggtgatgc tgctgtactt cttcaagcag aagactcaga
    18361 tcaagtgatc agcacaccct ctccaaaagg tgctccaaaa agagctctcc gctaccggtc
    18421 ggtatgcgcg ccccggcggc cttggggtgc ccgccgccgt ccaccccatt ctcgctggtg
    18481 aagtccgcca cgaagcggcc caggtccacg ctgtcccggg cgatcccccg cacggatacc
    18541 gatgaatatt ttcctcgggg gttgatcatg accgcgtaat cgcagccccg gcggtgcgcc
    18601 acctccacca aggcgcgagt gccgaagccg taaagtgtgc gattgtggtc catatcgtcc
    18661 attatgccca gggggccgcg caccttgatg ctgctgtcga ccttggccaa agcgcgaggc
    18721 caacgcttct cgttgaccac ctgggtatat cgtctcctca ccgaatccac ctgggagggc
    18781 cagacgccct gagagagcgc cttggccgtg atgtaccgga agcggtcgtc atcgattatc
    18841 aaacgccagg cgaagtctag gaccatcgat tcctggtcca ccctctgccg tccaaagcgt
    18901 cgcatctcct cgtccaggag cggcgtgggc atgtattcca ccaggtccgc cacggccacc
    18961 aatttccgca atcgcacctc ggggtgcagg tgatggaata gaacattggc cgcgctcacc
    19021 ccttccttga ccagggtggt gcagtccacg gccagggacg atggatgatg gtccaccagc
    19081 gtaagggatt gacaaagcct cttggctcga accgcctcga ccagatcggg cactggggcg
    19141 atatcgacca ggtatatctg gtccgagaag gtgtccatcg agagcacctt ggcgccagcg
    19201 gtaggagagg tgacgaaggt gaccttcgcg gtcgggaatc ggttcaagaa gatggcggcg
    19261 gaaacgatgc cgtcgacgtt gcctctggtt atgatatgct tgtcgcggtc atccctcgag
    19321 aagctaccgt ttcccatccg gtgaacaaaa tgggtctcca gactagataa atctatggtt
    19381 aattatctaa tttttagaat tgtcctcagt tagggttatt agacggatcg catgatacct
    19441 gagcgtgcgt agtctgcatc tactctcacc ggttatatga ttatcagaca gctcggtaat
    19501 ttggtgaata agtgacggac atatcctact ggggaaacag ccacatgggc ggccaggaaa
    19561 gcgaacttca gcagtgcttc gcccgggtgg gcatggagca cgggttcacc gatgtgaacg
    19621 ccaactggga gcggttcaag gagttcaagg ccacctggaa gcggtgctcg acgagcgcgg
    19681 agctgcacat taccgattac atgaaagagt ccggcgagcc tctcataact gacctggccc
    19741 ggggaatatt cggtcgcatg ggccggggcg gggtgaagga gatatactct gagagattga
    19801 agcaacattt cctgagcccg gagttcatac tgaggaacca gccgctgtac ttgcgaagga
    19861 gcaggaacct ggcctacgct cagatgggcc gagtgcacga cctgcgagcg ctggaacagg
    19921 acctgcacga tatcggattg gtcaagaggg tgccgcacgc ctacatgagc tggaccaaag
    19981 gcgacaatcg tcagcgagtg gggtattgca gcgtgatcat gcgggtggtg gctatcagcc
    20041 gtgtgctgga taggaaggag ataccttcgt tcgtgcccag ctacgtcctc tatcacgagc
    20101 tgatacacct ggagaacgga ctgcgcttcg gctcctatca cgatcgcgag ttccgggaga
    20161 gggaacgcat acaccctcat cacgaggagg cggaacggtg gctgaggagg gtcgtttccg
    20221 acccacagtt tcggtgaacg ggggagaact cttttaaggg accaatgaca aatgggatgt
    20281 gacaaagatg cgcaagacca tcaagatcaa cgagctgaag gcaggcggta cggtggacga
    20341 tctgttcgcg gtgcgcttca aaaagccagt gatgccttac aagaacggtt tcaccttcca
    20401 gatgtgggtg tccgacgccg ggggtgacat cgcggtgaag tactgggggg agaaggacga
    20461 aaagttggtc aaggccctct ccgacgccat atccaaaggc gcggtggtcc gggtgaacgg
    20521 aaaggtcacc gaatacaacg gcgccttaga gatacacgtg aacccctcat ccggtgattc
    20581 ggtagcggtc ctcaaggaag gcgagttcga ggtggccgat ttcgtggcct ccactaccga
    20641 ggacgtggag cagatgagag cccagctctt cgtcataatg agaaagatca aggacgtcca
    20701 tctaaaacag ttgctagaat cgttcttcgc tgacgaggag ttcgtcaagg agttctgttt
    20761 ctgtccggcg gccataaccc accattccaa ttacatcggg ggattgttgg aacacaccct
    20821 tcgcgtcgta aggacctgtg agcactatgc tcagcaatat ccagacctgg accgggacct
    20881 cctggtcacc ggggccatac tgcacgatgt cggtaaactt cgcgagtata ccgtgagcag
    20941 catcatcggc tctacggacg ccggtcggct ggtcggtcac ctggtcatcg gtgcgggcat
    21001 ggtcaacgac gcctgccgac tgctggggga cttccctccc gagcttaacc tgaaggtcca
    21061 gcatctggtc ctgtccagcc acggcacgaa ggaattcgga tctcccaagg aaccgctctt
    21121 ccctgaggcg ctggcattgg ccatggccga cctgtcgacg accaggatag aggacatgtt
    21181 gctggtcaag aagacggcta acaccgagga cgactgggtg caggataaga acgttgggtc
    21241 ggtatatctc aggtgagaac gtgcgtccat ccaacaaata tataaaaaaa taatattaat
    21301 gttatgattt tcgggatacg taacatttat tagcgatgtg cgtgagtatt atcttacaat
    21361 cgatgcggat gacacctacg caccggtaat gttgttcagg ctttagggat gctcggcatt
    21421 gaagtcacca acatcctatg cgacggtcag tgtcaacccc ggatcatcga cattcgccac
    21481 ggaggtgaaa gatgaccaag gagttcagct ggcatgacat agagatatcc gaagcatttg
    21541 acaggttggg ttcttccccg gacggtctga gcgagaccga ggccacggcg cggctgcggg
    21601 agcacggccc gaacgaactg gaccagaccg gagggatcaa cgcatggcat atgctcttgg
    21661 agcagctgcg taatcctctg aacttcgtcc tggtcgccgc cgcgctgata tctttcttcg
    21721 ccggcaagac cctggacacc gtggtcatcg ctatcatcat aatcttcaac accgccatgg
    21781 gcttcgtcca ggagttccgg gcggagaagg ccttgcaggc cctcaggtcc atggtcaccc
    21841 cggaagcgga ggttctccgg ccctgtgaag gtgcgaaggg agcgtgcgag gagatcaggg
    21901 tcaaggccga gcacctggtg cccggggacg tgctgctgtt agaggccggt gacaaggtcc
    21961 cagccgacgc ccgccttttc gaggcggcca acctggaggt ggacgaatcc atgctcaccg
    22021 gggaatccct cacggtccgg aagggcgtcg aggtgatgcc cgccggatcg ggggtggccg
    22081 accgcaagaa cctggtctat tccggcacca tcgtcaccca gggccgggcc cgggccgtgg
    22141 tgtattccac aggaatgagg acggagatag gcaagatcgc ccagctcatc ggaagcaccg
    22201 agagggccga gacacccatc caacgcagga ccaaagacct cagcaagaaa ctgggggcct
    22261 tcgcactgtt caccagcata ataaccctca ccgtaggttt cttcaaaggg ttcgagttca
    22321 ccgagatgct gctcttcgcc cttgcgtcgg ccgtttcggc cataccagag gggttgctgg
    22381 tggtattgac catcaccctg gccatcggag gccaccgtat ggtccgacgc aacgccctta
    22441 tccggaagct gcaggccgtg gagaccctgg gctcggtgac caccatctgt accgacaaga
    22501 cc
//
LOCUS       DAOPZI010000024        22159 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_2386_length_22159_cov_10.871245, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000024 DAOPZI010000000
VERSION     DAOPZI010000024.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 22159)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22159)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22159
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2386_length_22159_cov_10.871245"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..546
                     /locus_tag="PKM11_05770"
     CDS             <1..546
                     /locus_tag="PKM11_05770"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HNX48046.1"
                     /translation="PARETDPAVPISPYAASKLAAEYYCTLFYKLYGLQSVSLRYFTV
                     YGPRQRPDMAIRIFTDRALDGLHPQIFGDGEQTRDFTFIADVVDAIRRCADCPDPKGE
                     PLNICSGSTVSVNQVVSSILKAVDREDLKPEYLPPQPGDVDHTWGDSSKAKELLGWQP
                     KVKIDEGLSRFVDWYRKEGKI"
     gene            complement(543..1139)
                     /locus_tag="PKM11_05775"
     CDS             complement(543..1139)
                     /locus_tag="PKM11_05775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48047.1"
                     /translation="MKAYIRVIYSSDGSSPGQVDSVFQGKGFRKVPGVPGYEIDVLNE
                     GEMVQLLEELHVALKGLAVRYTPTLGTVEGQPTSGYRQRVIKLRDLNMEPMELSGLLE
                     QDASKFKEVAHEKLEAYLDSIIAERQDEMAVAEAKVMAERARVMLMDQLKEGRTFHEL
                     LKAVPIEEDELSQRLLELVEKGAIRAEQKGRSVVYVAV"
     gene            1230..2432
                     /gene="priS"
                     /locus_tag="PKM11_05780"
     CDS             1230..2432
                     /gene="priS"
                     /locus_tag="PKM11_05780"
                     /inference="COORDINATES: protein motif:HMM:TIGR00335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005658 - alpha DNA polymerase:primase
                     complex [Evidence IEA];
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of RNA
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase catalytic subunit PriS"
                     /protein_id="HNX48048.1"
                     /translation="MNREIEFAMDLFREYYRRSPPPAPADLRQREFGFMFFDRDFVRR
                     HMGFLEENDYRRFLVNQVPSHAYFSSALYQRPSAPTMDLKGWTGADLIFDLDADHIRG
                     ADGLSYQDMLILVKKEAMALVDRYIFGEFGFDDKYVKISFSGGRGYHVHVRDPRVRTL
                     GSHERGEIIDFVSGTDLDLDSLFPSSASMKKDFKEKVKVERAFRIPRKDEGGWRRFGR
                     GVMEKVAMEVGAMSNAGLRERYPSLQTAKEATLDDMRRSLHSRRGESTGLDLMMREDS
                     LEYFTSDRVKELFIQMVLQSLKERMAGQIDEPVTRDIKRLIRLPGSLHGKTGLKVVTL
                     SRDQMNDFDPLRDAVPDTYPDRPVKVRLKDNTSIRIRDCQVQGTGDVEVPAYAALFLV
                     LRRMGTLV"
     gene            2492..3331
                     /locus_tag="PKM11_05785"
     CDS             2492..3331
                     /locus_tag="PKM11_05785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48049.1"
                     /translation="MKYDSGHFEGGYRLMHIHNTKRYLFLVQAVLIMIFAVYLVYAGG
                     GFSVKPFYLGINSFLYFVLLMVLLIMIESYIFTALEMRFVKSDSAKFLITQRTFRTAL
                     VWAVVWMLILLAFALPFLPGAVKDTTQSEGRLTAISSVEPANFVVLNTDMFGFTEVST
                     IHVTALGEVEVFVLTEYNYLLFKNEGAGVLGGYRVNVNDYLASPELTIDFPDMPHGRF
                     YVLFYSLNDVPVDIDYTVEREVSKTLMDYMPLMSIAFVVINAAAAIYMMLLNRNYKAG
                     IYQ"
     gene            complement(3322..4134)
                     /locus_tag="PKM11_05790"
     CDS             complement(3322..4134)
                     /locus_tag="PKM11_05790"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48050.1"
                     /translation="MRTISVYRPGKAFPSVSVTGTRCELMCEHCRGRFLEGMAPVDGP
                     GALFSLAHELAAKGGSGLLLSGGCDAQGRVPLLPYIDAIREIKRTTPLLINLHPGLVS
                     EEEARKLARSGADRFSFDLVLDQRLVSEGMHLSPSSLNHTDSFLALCRAAPGRVAPHV
                     LLGAGDEEREMEAVRTACGQDIACLVLLSLIGRKVDDWEGRLLRAVEEGRRLQRPVLI
                     GCMRPRGRPDVEMAALEAGAAGLANPAKGTMTAINERGWAVQERAVCCALHW"
     gene            4204..4446
                     /gene="rpl18a"
                     /locus_tag="PKM11_05795"
     CDS             4204..4446
                     /gene="rpl18a"
                     /locus_tag="PKM11_05795"
                     /inference="COORDINATES: protein motif:HMM:NF001981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18Ae"
                     /protein_id="HNX48051.1"
                     /translation="MKGFQVTGSYDASRVGYRQSIQNFSVQVAAVDENAAREKVLSEL
                     GSKHRKKRTEITLKEVKTLAAADVTDPIVKHQIGEK"
     gene            4446..4871
                     /gene="pfdA"
                     /locus_tag="PKM11_05800"
     CDS             4446..4871
                     /gene="pfdA"
                     /locus_tag="PKM11_05800"
                     /inference="COORDINATES: protein motif:HMM:TIGR00293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prefoldin subunit alpha"
                     /protein_id="HNX48052.1"
                     /translation="MNEQEMRQAMGALEAYKAQLEAINEQGQLLQMSLEDYSRAKDTL
                     DAVGKGQPGDEVLMPVGGSAYVYASIVRSDRVLVGVGTGVSIDKPMEDAVALVDARIG
                     ELMDAMKKVSESRTVIESKMQQLSQMVQQEYQRMQQGHK"
     gene            4879..5817
                     /gene="ftsY"
                     /locus_tag="PKM11_05805"
     CDS             4879..5817
                     /gene="ftsY"
                     /locus_tag="PKM11_05805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HNX48053.1"
                     /translation="MFESLKKILGLSKKDIEPSVKVEEVVGDSGKKISEKDLDDLLWD
                     LEIVLLEADVALPIVEEIKASVRGDLLGKRVDRSYRVEDAIEMALKNAVLKVLKGSEF
                     DFDSFIAAHEKPVVVMFLGINGTGKTTAIAKLTKRLQGQGFSVILSASDTFRAGAIEQ
                     ITIHADRLGSKVIKHQAGGDPAAVAYDALEHAKARKRDVVLVDTAGRMQTNSNLMDEM
                     KKIKRVVKPHLTVFVGDSLAGNDAIEQARTFDKEIGIDVVILTKIDTDAKGGAALSIA
                     HSIKKPIAFLSTGQGYDDIIKFDSQWMIDRLFNEKK"
     gene            complement(5830..7080)
                     /locus_tag="PKM11_05810"
     CDS             complement(5830..7080)
                     /locus_tag="PKM11_05810"
                     /inference="COORDINATES: protein motif:HMM:NF010589.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HNX48054.1"
                     /translation="MPGLEQLLAQVGSHRDEMVEALSELIRIPAIGPESGGSGELERS
                     RYLRDILDHSKFDDVEMYDALDERVRLRLRPNIVAKKKGKTDQTVWIVAHMDTVPPGD
                     LNAWKTPPFSPRLVDGKLYGLGSEDNGQALIAGLFAAETLMSMDVELERSLGLVLVAD
                     EEMGNERGIKFLLKEGVFKQGDIMFVPDHGTPRGDEVEIAEKHILWLKFTVTGKQVHA
                     SRPDLGTNAMRVGSELIVFLQDFLHRKYNGRDELFTPDRCTFEPTKRLQTVGNVNTIP
                     GEDVFYFDCRILPQYDIDALRSDITAVLDIFEQKSGTQISMETVQETRSGPPSDLEGE
                     GMKALKWAVKRVKGIEPKPVGIGGGTCANFFRLAGMNAYVWQTIEELAHTPNEYCVVD
                     NLVEDTKVFAVVLAALCCGSQFQA"
     gene            complement(7133..8308)
                     /locus_tag="PKM11_05815"
     CDS             complement(7133..8308)
                     /locus_tag="PKM11_05815"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HNX48055.1"
                     /translation="MQDVVIISAARTAIGKFNGTIKDVPATQLGATAIKEAVKRSGLQ
                     PADIEECIMGNVLSASLGQNPARQAAVGAGLPYEIGSTTINKVCGSGMKAVMLAANAI
                     KAGEYQAIVAGGMENMNSAPFLLKQARFGYRLGDNKIVDHMVNDGLWDVFNDMHMGIT
                     AEIVAERFNVTREQADLLSYRSHQNAQRAQSEGRFDKEIVPIVMKGKKGDTVFDKDEG
                     IRADTTPESLAKLSPAFKKDGLVTAGNASQLSDGAAALVVCSREFAESKGIKPLAEIV
                     GYATGGTRPEWIMEAPIPATRKLLDKLNMDINEFDLFEHNEAFATASVAVRKELGVPE
                     DRFNVNGGAIALGHPIGCSGARVLVSLIHALKDQGKSTGLATLCLGGGNAVSMAIRI"
     gene            complement(8387..9694)
                     /locus_tag="PKM11_05820"
     CDS             complement(8387..9694)
                     /locus_tag="PKM11_05820"
                     /inference="COORDINATES: protein motif:HMM:NF020078.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Ile)(2)-agmatinylcytidine synthase"
                     /protein_id="HNX48056.1"
                     /translation="MFVAFDDTDSLESMCTTFLATEMIKALGVYDLIGLPRLVRLNPA
                     VPWKTRGNGALCLRFGVGRGECDMVGELDGAPVYSYKRMYEEADRVLVLDVAERIVAK
                     WSRTTEGASPGLVVSERKPAQSLYWSAVRSIVRKEDTLRELQRIGADMVGWEGGRGII
                     GASAAMAWKPRDSTYEIITYREKERWGTPRYLDDLSVKEMDLRYPSTFNNFDHHIGRR
                     AISPHTPCPVLFGVRGDDPKELMSAVFSLRSEPPARWIMFLSNQGTDDHLIRGEPSLP
                     DRSYDVLATVSEAPRTVTGGHVIFQVTTSKGNLDCAAYEPTKEFRDIVRELRPGDRLR
                     LFGELRAEPRTLNIEKFQLISIAPEQKKVANPRCPVCEGPTKSVGSAGGFRCKKCGRK
                     NDLEPLMEEVARSISPGWFEPPVCARRHLGKPLKRMGQERHQP"
     gene            9779..10126
                     /locus_tag="PKM11_05825"
     CDS             9779..10126
                     /locus_tag="PKM11_05825"
                     /inference="COORDINATES: protein motif:HMM:NF022873.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3198 domain-containing protein"
                     /protein_id="HNX48057.1"
                     /translation="MSKPMNVERGLELSVLITVLGAVLLFLGISDALDWVIDLRGWGF
                     YTGAIGVISLIVGVIWAISIVQRMRRFDVLIEEKSKAVFVRNLDDIEYTAWRLPSKYD
                     VRLDEKKRKMGVK"
     gene            complement(10258..11526)
                     /gene="hflX"
                     /locus_tag="PKM11_05830"
     CDS             complement(10258..11526)
                     /gene="hflX"
                     /locus_tag="PKM11_05830"
                     /inference="COORDINATES: protein motif:HMM:TIGR03156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HNX48058.1"
                     /translation="MKKGALISLDRETAEIEELCRSADIEILYVVMQRRARPDRSHYL
                     GKGRFNELKELLLERPVDVVVINGELKPSQHFNLENGLKVECLDRIAVVLDIFTSRAE
                     GRESKLQVELARLNYQVPLMREWVHSAKAGEHPGFLGGGEYQVDVYYNIIRRRIAQID
                     EELRSLARDGDLRRGVRHFKGFRTVCLAGYTNAGKSSLMRRLTGEEVLVADRMFSTLG
                     TTTRRVGSSKILLTDTVGFLKDLPHFMVESFRNTLQDVFTADLVILVVDSSEPLFKVS
                     SKMVAVQEILGKGQMKGKMVVVLNKMDQDPDGLTEMISAVNEILDPLSVIGVSAVTGY
                     GIDELMDFMQSYFRPSVVVSFKAANSKSSATEISRLYDDHFVESVVYSNLVEVVFRCH
                     EDDLEKVMDRLYSLPGIKDVSSAVDSRYVR"
     gene            11761..12999
                     /locus_tag="PKM11_05835"
     CDS             11761..12999
                     /locus_tag="PKM11_05835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORC1-type DNA replication protein"
                     /protein_id="HNX48059.1"
                     /translation="METNVFTQHMDRRQIFKKNNREILRPSYIPDVLPHRQEEINSLA
                     SVLVTALKGERPSNILIFGKTGTGKTACVKFIGNEIKKAGGEEATVTFIYMNCEVVDT
                     SYGVLQNIGNQFVKDFDQRIPFTGLSIMQVYNMLRDKLDEQNHVIIIALDEIDKLVYK
                     SGDDVLYHLSKINDDLKKARVSVIGISNDLLFTEMLDPRVRSRMEGEKMVFPPYNADQ
                     LKDILRQRSSLAFDEGVLEEAVIPLCAALAAQEHGDARRALDLLRIAGEIAERENSEK
                     VQELHVLKAKNKMELDTVSEAIRTLPTQSKMVLMCIVTNVERGTEKLTTGDVYETYKE
                     MSRILGMGPLTQRRITDLISELDMMGIIHARVRSFGRGGRTKEIDLSVPLAETKKVLE
                     EDDVFVSLKHYKQRNQTTLM"
     gene            complement(13000..13911)
                     /locus_tag="PKM11_05840"
     CDS             complement(13000..13911)
                     /locus_tag="PKM11_05840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="S26 family signal peptidase"
                     /protein_id="HNX48060.1"
                     /translation="MSDASGKLWNVVRQYKVLVGGLLTMAILLLAVFIYAGMWPPVYV
                     VESESMQHSDDRSFIGTIDTGDLVIVQSSDGSDVRTYVESYPDGHRTFGDYGDVIVYE
                     RYGWSDYTPIIHRAMLRLEYNSTSSSFDIPSLAGLPAEKWGNGPLEDGRWWNLTDVVE
                     VYDVGYRSAVLRVDLLELLSFYADHELDHDGIITMGDHNVREIGGTYIGFYDQYPGAA
                     VCREPVMDEWIIGEAKAELPWLGLIKLWVNGNMPANTPDNSKNALLIVLALVIVVPLA
                     MDMTGLVLQRRGIDVWARIRERMRRKK"
     gene            13989..14447
                     /locus_tag="PKM11_05845"
     CDS             13989..14447
                     /locus_tag="PKM11_05845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HNX48061.1"
                     /translation="MSNRPDNDTYFMRMAELVATRSTCLRRQVGAVIVKEKRVLTTGY
                     NGAPRGLKHCEEVGCVRQQNNVESGTRHELCRGVHAEQNAVIQGAYFGASIKGATVYT
                     TNFPCVLCSKIMLNAGIEEIVYLDTYVDELSKQMLEEAGIKVRRYERPLL"
     gene            14663..15007
                     /locus_tag="PKM11_05850"
     CDS             14663..15007
                     /locus_tag="PKM11_05850"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48062.1"
                     /translation="MNRSDILLQVKDAESKAQQIVKEAEEKQRSTVTSARREAAARVN
                     EADEKLRAEYDSRFAKERESIASEKQAYLNKGKEEAAAVKAKAEGKVPNVITHLMQSF
                     ERTLDVAAKTND"
     assembly_gap    15062..15161
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <15162..16404
                     /locus_tag="PKM11_05855"
     CDS             <15162..16404
                     /locus_tag="PKM11_05855"
                     /inference="COORDINATES: protein motif:HMM:NF013647.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033179 - proton-transporting V-type
                     ATPase, V0 domain [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="V-type ATPase 116kDa subunit family protein"
                     /protein_id="HNX48063.1"
                     /translation="TFAMDAWVPTSEMPTVEKAINEKLAGKVHVESLEVMSRREAHGH
                     HDAEQHDAPVEEIPSKTENGKTVSKFEFMARMLSTPKYREIDPAVTMMITIPIFFGLM
                     VGDIGYGIPFMILGLIGLKKCVSDEWRTISTLLFFGGIWASIFGLFMFGEAYGIHFAE
                     QAHDMSWSSLLGVHLPHEIAIGGFEIPLGIYSKLHNVKEILYMTLWIGIAHIFIGFCI
                     GFYNKSIRFGFKHAVIEKISWLMILVGGALLLLFLVDAMIRGLTVELTDIRMLIALPL
                     IVIGILMAYKGEGSGAILELPGLMGNIISYTRLAAIGMSKAGLALAFNTIAFEVMWGH
                     DFHVMGSNSGDTIMLIAALAIFLIGHLTIFVLAIISAGLHSLRLHYVEFFMKFYEGGG
                     VEFKPLKVIRKYTTDKNGVSE"
     gene            16406..16624
                     /locus_tag="PKM11_05860"
     CDS             16406..16624
                     /locus_tag="PKM11_05860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HNX48064.1"
                     /translation="MADAGLIAIGAGIAVGITGLASAWAEKEIGSAAIGAMAENEKLF
                     GKGLILTVIPETIVIFGMVVAILLWLNM"
     gene            16671..17228
                     /locus_tag="PKM11_05865"
     CDS             16671..17228
                     /locus_tag="PKM11_05865"
                     /inference="COORDINATES: protein motif:HMM:NF014093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033178 - proton-transporting two-sector
                     ATPase complex, catalytic domain [Evidence IEA];
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E family protein"
                     /protein_id="HNX48065.1"
                     /translation="MALDEVISSVTESAQARAKELSAEADKEKAAILRQADDKIAAKR
                     LAQQKELEVSIKRLKQQDISSAELEAKRIVLNAKKDVMDRSFQEALSSLLNMDEGNRG
                     RMYRKILEGGKTVIQSPKVFCPRGESKLISGVAGLGKVEEADMEAGLVLEDASGNVRL
                     DYRFRVILESVWDKELKNVSNILFG"
     gene            17233..18294
                     /gene="ahaC"
                     /locus_tag="PKM11_05870"
     CDS             17233..18294
                     /gene="ahaC"
                     /locus_tag="PKM11_05870"
                     /inference="COORDINATES: protein motif:HMM:TIGR02923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase A1 subunit C"
                     /protein_id="HNX48066.1"
                     /translation="MLSIWGSKGNYAYVTARVKAKKSLLISKDNYPKLMLMDLNEIGR
                     FLGETQYQVEMTELATKYDGVNLIELGTSKNLARVFTDILNYSKGDLRDMLERYLMRW
                     DIWNIKTILRGKYYGASTEDILEDIVAAGKYDEGFINILISLEDVEAVLKELKSKEGL
                     VIPDEVVEEYQETKTLAPIEDYLDRLYYDEVLACVKCRDKAERLFKQFLRKEVDVTNL
                     MTLLKLKKEGLSPEHPEKYFIDGGEELQIKTLVELSKAENVERLGSELTKFSFYADIK
                     DALEEFKQTGSLSTVSLAMQRHLLRSSEKFSHIYPLSVLPIMDFMLRKKQEVDNIRII
                     ARCKESDLGPDQIKKLLVM"
     gene            18294..18593
                     /locus_tag="PKM11_05875"
     CDS             18294..18593
                     /locus_tag="PKM11_05875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HNX48067.1"
                     /translation="MDIAVLGSDEFVLGFRLGGVKRIYTAKTNDYEAKALELIADSSI
                     GVLAIDSSDLELLSPNARRKVTENIAPVVVMVGKAESDLREKVKRAIGVDLYKTN"
     gene            18604..20334
                     /locus_tag="PKM11_05880"
     CDS             18604..20334
                     /locus_tag="PKM11_05880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HNX48068.1"
                     /translation="MGKEGVIYRVAGPVVTAVGISPRMYDVILVGKEQLMGEVIKIVG
                     EKTIIQVYEDTSGVRPGEKVVDTEQPLVAELGPGLLSSVYDGIQRPLPVLMEKMGNFI
                     ERGVSAPGLDHNLKWPFTPVVKQGDKVTEGQIIGTVPERAITHKVMVPPGISGTVDMI
                     KSGEFTVDEIVAVIDGKEVRMMQKWPVRRGRPFAKKTAPDEPLITGQRVCDTFFPLTK
                     GGTAAIPGGFGTGKTVTQQQLAKWSDAEIVVYIGCGERGNEMTEVLTSFPELKDPKTG
                     KPLMNRTVLIANTSNMPVAAREASVYTGMTIAEYFRDMGLNVSLMADSTSRWAEAMRE
                     ISSRLEEMPGEEGYPAYLSARLSEFYERAGSVIALSGKTGSISVVGAVSPPGGDLSEP
                     VTQNTLRIVRVFWALDTKLRERRHFPAINWLTSYSLYSGQLDGWYKKNVAEDFPELRN
                     WAVGLLQKEAELQEIVQLVGSDALPDEQKLTLEITRMIREIFLQQNAYHPVDTYSPMG
                     RQYTYLKLINRFSTYASKAVENEVSVEAIANMALRNRLAKSKFEDNIEGELKAIAETM
                     EKEFEALGGK"
     assembly_gap    20382..20481
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <20482..21513
                     /locus_tag="PKM11_05885"
     CDS             <20482..21513
                     /locus_tag="PKM11_05885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HNX48069.1"
                     /translation="WARDNPSEFIQTGISTIDGMNTLVRGQKLPIFSASGLPHNEIAL
                     QIARQAKVLGGSEDFAVVFAAMGITNEEAQYFMKDFERTGALKRAVVFLNLADDPAIE
                     RIITPKLALTTAEYLAFTLDMHVLVILTDLTNYCEALRQIGAAREEVPGRRGYPGYMY
                     TDLAGIYERAGRIKGKKGSITQIPILSMPGEDITHPIPDLTGYITEGQIVAKRELLRA
                     GIYPPIDVGSSLSRLMNEGIGPGRTRDDHKAVSDQCYAAYAEGRDLRGLVAIVGKEAL
                     SERDRKFLEFADDFEKRIVQQGRDEDRTIEGTLDLMWEILASLDERQLTRIDRKYIEK
                     YHPKYRKKD"
     gene            21515..22150
                     /locus_tag="PKM11_05890"
     CDS             21515..22150
                     /locus_tag="PKM11_05890"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HNX48070.1"
                     /translation="MSTADVKPTRSELLEIKKKIKLTKSGYKILKMKRDGLIMEFFKI
                     LAQAKDIRDKVNHDYAEAMRSIAIAKAVDGAIAVQSAAFALKTHPELSLRSKNIMGIV
                     VPEIEANSIRTPMDQRGYGVIGTSVYIDEAAKAFENLVETVIEAAEIETTMKKILDEV
                     EKTKRRVNALEFKVIPELQESEAFIRLRLEEMERENTFRLKRVKQKAEARG"
BASE COUNT         4704 a         6443 c         6435 g         4377 t
ORIGIN      
        1 ccggcccggg aaacggaccc cgcggtgccc atatccccgt acgccgccag caagttggcc
       61 gccgagtact attgcacctt gttctacaaa ctgtacggac tgcagagcgt ctccctgcgc
      121 tacttcacgg tttacggccc gagacagcgg ccggacatgg ccatacgcat attcaccgac
      181 cgcgctttgg atgggctgca tcctcagatc ttcggcgacg gggagcagac cagggacttc
      241 accttcatcg ccgacgtcgt cgacgccatc cgccgttgcg ccgattgccc tgatccgaag
      301 ggcgagccgc tgaacatctg cagcggatcc accgtcagcg tcaaccaggt cgtttcgtcg
      361 atactgaaag cggtcgaccg cgaagacctg aagccggaat atctcccacc gcagccgggg
      421 gacgtggacc acacctgggg cgacagctcc aaggcgaagg agctgctggg ctggcagcca
      481 aaagtaaaga tagacgaggg gctgagccgc ttcgtcgatt ggtatcgaaa ggaaggaaaa
      541 atttagaccg cgacgtagac cacgctgcgg cccttctgct cggcccggat cgctcccttt
      601 tcgaccagtt cgagcagcct ctgggagagc tcgtcttcct ctatggggac ggccttcagt
      661 agctcgtgga aggtgcggcc ctccttcagc tggtccataa gcattacccg ggcgcgctcg
      721 gccatgacct tcgcctcggc tacggccatc tcgtcctgcc tctcggcgat tatggaatcc
      781 aggtaggcct ccagcttctc gtgcgcgacc tccttgaact ttgaggcgtc ctgctccaga
      841 agtccggaga gctccatcgg ctccatgttc aggtcgcgca gcttgatcac cctctggcga
      901 tagccggagg tcggttgccc ctctacggtc cccagggtgg gcgtgtagcg gaccgcgagc
      961 cctttcaggg ccacgtgcag ttcctctagt aactgaacca tctcaccttc gttcagaaca
     1021 tcgatctcgt atccagggac cccggggacc tttctgaacc ccttgccctg gaacaccgaa
     1081 tcgacctgcc cgggtgagct gccgtcgctg gaatagatga ccctgatgta agctttcata
     1141 ccgatcggga gaaaatattc tgtgttgtct atatagtttg gtattggttt attacaacct
     1201 atttattcgc cataggacat gggggaaccg tgaacaggga gatcgagttc gccatggacc
     1261 tcttccggga gtattaccgg aggtccccgc cgccggcccc ggccgacctc cggcagcggg
     1321 agttcggctt catgttcttc gatagggact tcgtgaggag gcacatgggc ttcctggagg
     1381 agaacgacta ccgccggttc ctggtcaacc aggtgccctc gcacgcttac ttctcttcgg
     1441 cgctgtatca gcgcccgtcc gccccgacca tggacctcaa gggctggacg ggggcggacc
     1501 tcatcttcga cctggacgcc gaccacattc gcggcgcgga cggcctctcc tatcaggaca
     1561 tgctcatcct ggtgaagaag gaggccatgg ccctggtgga ccgctacata ttcggggagt
     1621 tcggcttcga tgataagtac gtcaaaataa gcttctccgg gggacgcgga tatcacgttc
     1681 acgttcgaga tcctagagtg cgcaccctcg gctcgcacga gcgcggcgag atcatagatt
     1741 tcgtcagcgg aacggacctg gacctggaca gcctgttccc gtccagcgcc agcatgaaga
     1801 aggacttcaa agagaaagtt aaagtggagc gggcgttccg catcccgcgg aaggacgagg
     1861 ggggctggcg tcgcttcggg cgcggggtga tggagaaggt ggccatggag gtcggggcga
     1921 tgagcaatgc ggggcttcgc gagcgctatc cgtccctgca gaccgcgaag gaggccacgc
     1981 tggacgacat gagacgctcg ttgcattcca ggcggggcga atcgaccgga ctggacctca
     2041 tgatgcgcga agatagtctg gaatacttca cctccgaccg ggtcaaggag ctattcatac
     2101 agatggtcct gcagtcgcta aaggaaagaa tggccggcca gatcgacgag ccggtgacca
     2161 gggacatcaa gaggctgata cgcctgcccg ggtccctgca cgggaagacc gggctgaagg
     2221 tggtcacgct ttccagggac cagatgaacg atttcgatcc tttgcgggac gcggtgccgg
     2281 acacctaccc ggaccggccg gtgaaggtgc gtctgaagga taacacatca atacgcatac
     2341 gggactgcca ggtgcaaggg accggggacg tcgaggtgcc ggcctacgcc gccctgttcc
     2401 tggtcctgcg ccgaatgggc accctggtct agtcgctcct ggcccgacag gaatctttat
     2461 taagtggcca gggaattatt tgcgggacct catgaaatac gacagcgggc attttgaagg
     2521 cggttatcgc ctgatgcata tccacaacac caagaggtac ctgttcctgg ttcaggccgt
     2581 cctgatcatg atcttcgccg tctatctggt ctatgccggg ggcgggttca gtgtcaagcc
     2641 cttctacctg ggcatcaact ccttcctgta cttcgtgctt ctgatggtcc tgttgatcat
     2701 gatcgagtcg tacatcttca ccgccctgga gatgcgcttc gtcaaaagcg acagcgccaa
     2761 gttcctgatc acccagcgca cgttccgaac cgccctggtt tgggccgtgg tctggatgct
     2821 catactgctg gccttcgccc tgccgttcct gccaggggcg gtgaaggaca ccacccagag
     2881 cgagggacgg cttacggcca tctcctcggt ggagccggcg aacttcgtgg tgctcaacac
     2941 cgacatgttc gggttcaccg aggtgtccac catccacgtc accgccctgg gcgaggtgga
     3001 ggtgttcgtg ctcaccgagt acaactacct gctcttcaag aacgagggcg cgggcgtcct
     3061 gggcggttac cgggtgaacg tgaacgacta cctggcctcc ccggagctga ccatagattt
     3121 cccggacatg ccgcacggcc ggttctatgt cctgttctac tcccttaatg atgtcccggt
     3181 ggatattgat tacaccgtcg aaagggaggt ctcgaagacc ctgatggact acatgcccct
     3241 gatgtccatc gccttcgtgg tgatcaacgc cgcggcggcg atttacatga tgctgttgaa
     3301 ccggaactac aaggccggca tctaccagtg aagggcgcag cacaccgccc tctcctggac
     3361 cgcccatccc ctttcattga tggccgtcat cgttcccttg gccggattgg ccaggcccgc
     3421 cgctcccgcc tccagcgccg ccatctccac gtccggacgg ccgcgggggc gcatgcaacc
     3481 tatcagcacc ggtcgctgaa gccttcggcc ctcctccacc gcccgcagca gccgcccctc
     3541 ccaatcgtcg accttccttc cgatcaggga gagaagcacc aggcaggcta tgtcctgacc
     3601 gcaggcggtg cgcaccgcct ccatttcccg ttcctcgtcc cccgccccta gaagcacgtg
     3661 cggcgccacc cttcccgggg cggcgcggca cagggccagg aacgagtccg tgtggttcag
     3721 ggaggagggc gataggtgca ttccctccga gaccagacgc tggtccagca ccagatcgaa
     3781 ggagaaacgg tcggcgccgc ttctcgccag cttcctcgcc tcttcctccg agaccagccc
     3841 ggggtgcagg ttgatgagca gcggggtggt cctcttgatc tcccttatcg catcgatgta
     3901 gggaagcagg ggcaccctcc cctgggcgtc gcatcccccg ctgagaagga ggccgcttcc
     3961 gcccttggcc gccagttcat gggccagtga aaaaagagcc cccggaccgt cgacgggcgc
     4021 cattccttcc aggaagcgcc cgcggcagtg ctcgcacatc agctcgcacc gcgttccggt
     4081 gaccgagacc gaagggaacg ccttaccggg ccggtagacg gagatggtcc gcatgatcgg
     4141 aggatggtct cccgaccaaa agctttattg ggtgaacccc gttcctcggc cgaggcaacc
     4201 ccgatgaaag gttttcaggt taccggctca tatgatgcta gcagagtagg ctaccgccag
     4261 agcattcaga acttcagcgt ccaggtggcc gccgttgacg agaacgcggc ccgagagaag
     4321 gtcctgtccg agctgggcag caagcaccgc aagaagcgga ccgagatcac cctcaaagag
     4381 gtcaagacgc tggctgcggc tgacgtgacc gacccgatcg tcaagcacca gatcggtgag
     4441 aagtgatgaa cgagcaggag atgcgccagg ccatgggcgc cctggaggcc tacaaggccc
     4501 aacttgaggc gatcaacgag cagggccagc tcttgcagat gtccctggag gactattccc
     4561 gggccaagga cacactggat gcggtgggca agggccagcc tggcgatgag gtcctcatgc
     4621 cggtgggagg cagcgcttac gtctacgctt ccatcgtccg cagcgaccgc gtgctggtcg
     4681 gggtcggcac cggagtttcc atcgacaagc cgatggagga tgccgtggcc ttggtcgacg
     4741 cgcgcatcgg agagctgatg gatgccatga agaaggtcag cgagagccgc acggtcatcg
     4801 agtccaagat gcagcagctc tcccagatgg tccagcagga atatcagagg atgcagcagg
     4861 gccacaagtg aaggggccat gttcgaatcc ctgaagaaga tcctcggcct tagcaagaag
     4921 gacatcgagc cttcggtcaa ggtcgaggag gtcgtcggcg actccgggaa gaagatctcg
     4981 gagaaggacc tggacgacct gctctgggat ctggaaattg ttcttttaga ggcggatgtc
     5041 gccttaccca tagtggagga gatcaaagcc tccgtacgcg gggacctcct cggcaagcgg
     5101 gtcgatcgct cctaccgggt ggaggatgct atcgagatgg ccctgaagaa cgccgttctg
     5161 aaggtcctaa agggaagcga gttcgatttt gattccttta tcgccgctca cgagaagccg
     5221 gtggtggtca tgttcctcgg gataaacgga actggcaaga ccacggccat tgccaagctc
     5281 accaagcgcc tgcaggggca gggcttcagc gtcatcctat ccgcgtccga taccttccgg
     5341 gccggagcga tagagcagat caccattcac gccgaccgct tgggtagcaa ggtcatcaag
     5401 catcaggccg gaggagaccc tgcggcggtc gcctacgatg cgttggagca tgccaaggcc
     5461 cgcaagaggg acgtcgtgct ggtagatacc gccggacgca tgcagaccaa ctccaatctc
     5521 atggacgaga tgaagaagat caagcgggtg gtgaagccgc atctcaccgt cttcgtcggc
     5581 gattccctgg cgggaaacga cgccatcgaa caggcgcgta cgttcgataa ggagatcggc
     5641 atcgatgttg tgatcctgac caagatcgac accgacgcca agggcggcgc cgctctgtca
     5701 atcgcgcact ccatcaaaaa gcccatagcc tttctttcta cggggcaggg ctacgacgac
     5761 atcatcaagt tcgacagcca gtggatgatc gaccggctgt tcaacgaaaa gaagtagtga
     5821 agaggttttt caggcctgga actggctgcc gcaacaaagt gccgccagga ccaccgcgaa
     5881 caccttggtg tcctcgacca ggttgtccac gacgcagtac tcgttcgggg tgtgtgccag
     5941 ctcctcgatg gtctgccaga cgtaggcgtt cattcctgcc aaacggaaaa agttggcgca
     6001 ggtgccgccg ccgatgccga ccggtttcgg ctctatgccc ttgacccgtt tcaccgccca
     6061 cttcagggcc ttcatgccct ccccctccag atcggacggc ggaccgctgc gggtctcctg
     6121 caccgtctcc atgcttatct gggtgccgga cttctgctcg aagatgtcca gcacggcagt
     6181 gatgtcgctg cgcagcgcgt cgatgtcata ctgaggcaat atgcgacagt cgaagtagaa
     6241 gacgtcctcg ccggggatgg tgttgacgtt tccgacggtc tgcaaccgct tcgttggttc
     6301 gaaggtgcag cggtccgggg tgaacagctc atcgcggccg ttgtacttgc ggtgcaggaa
     6361 gtcctgcagg aacacgatca gctcggaacc gacgcgcatg gcgttggtgc ccaggtccgg
     6421 ccgggaggcg tgcacctgct tgccggtgac ggtgaacttc aaccacagga tgtgcttctc
     6481 ggcgatctcc acctcgtcgc cgcggggcgt tccatggtca ggaacgaaca ttatgtcgcc
     6541 ctgcttgaag acgccctcct tgagaaggaa cttgatgccg cgctcgttgc ccatctcctc
     6601 gtcggccacc aggaccagcc cgaggctgcg ctccagctcc acgtccatgg acatcaacgt
     6661 ctcggcggcg aacagtccgg cgatgagcgc ctgaccgttg tcctccgacc ccagcccata
     6721 gagcttgccg tccaccagtc gcggtgagaa cggtggcgtt ttccaggcgt tcaggtcgcc
     6781 cggcgggacg gtgtccatgt gcgccacgat ccagacggtc tggtccgtct tgcccttctt
     6841 cttggccacg atgttcggcc tcagccgcag cctgacccgc tcatcgagcg cgtcgtacat
     6901 ctccacgtcg tcgaacttgg agtggtccag gatgtccctg aggtagcggg acctttccag
     6961 ttcgccgctc cctccgctct ccggaccgat ggccggtatc cttatcagct cgctgagggc
     7021 ctcgaccatc tcgtcacggt gggaacccac ctgagccagt aactgttcca gaccgggcat
     7081 ttgaatcgac aataattgtt attgcactta taaaatgtat tggtaaagtg ttttagatcc
     7141 ggatggccat ggacacggcg ttccctccgc ccaggcagag agtggccagg ccagtgctct
     7201 tgccctggtc cttgagggcg tgtatgagcg agacgagcac ccgcgcaccc gaacacccta
     7261 tgggatggcc gagggctatg gccccgccgt tgacgttgaa acggtcctcc ggaacgccta
     7321 gctccttgcg caccgccacg gaggcggtgg cgaacgcctc gttgtgctcg aacaggtcga
     7381 actcgtttat gtccatgttc aacttatcta acagtttgcg ggtggccggg atgggcgcct
     7441 ccatgatcca ctccgggcgg gtgcccccgg tggcgtaacc cactatctca gcgagtggct
     7501 tgataccctt ggactcggcg aactccctgg agcagaccac cagcgcggcc gctccgtcgc
     7561 tgagctgcga ggcgttcccg gcggtgacca ggccgtcctt cttgaaggcc ggggatagct
     7621 tggctagcga ttccggggtg gtgtcggcgc gtatgccctc gtccttgtcg aaaacggtat
     7681 cgcccttctt ccccttcatc acgatcggca ctatctcctt gtcgaaccgc ccctcggact
     7741 gcgccctctg cgcgttctga tgtgatcggt acgagagcag atcggcctgc tccctggtga
     7801 cgttgaaccg ctcggccacg atctcggcgg tgatgcccat gtgcatatcg ttgaacacgt
     7861 cccatagacc gtcgttcacc atgtggtcca cgatcttgtt gtcccccagt cgatagccga
     7921 agcgggcctg tttcagaagg aacggggcgg agttcatgtt ctccatgccc ccggccacga
     7981 tggcctggta ttcgccagcc tttatagcgt tggcggccag catgaccgcc ttcatccccg
     8041 acccgcagac cttgttgatg gtggtggaac cgatctcgta cggcagcccg gcgccaaccg
     8101 ccgcctgcct tgcggggttc tgccccaagg acgctgacag gacgttgccc atgatgcatt
     8161 cctcgatgtc cgccggctgc aggccggagc gcttgaccgc ctccttgatg gcggtcgccc
     8221 ccagctgggt tgccggcacg tccttgatgg tcccgttgaa cttgcctatg gcggtcctgg
     8281 ccgcactgat gatgacgaca tcctgcatga tatttccctc gccagctaac tggtcaggtt
     8341 tttcttctca tagaacgacg gggtataaat ctatgtcgat tatgccctac ggctggtgtc
     8401 gttcctggcc catgcgcttg agcggtttgc cgaggtgccg acgggcgcag accgggggct
     8461 cgaaccaccc cggggagatg cttctggcca cctcttccat cagcggctcc aggtcgttct
     8521 ttcttccgca tttcttacaa cggaagccgc ccgcggaccc cacggacttg gttggtccct
     8581 cacagaccgg gcagcgcgga ttggccacct ttttttgttc gggagcgatg gatatcaact
     8641 ggaacttctc tatgttgagc gtcctgggct ccgcccgaag ctcgccaaat aaacgcagac
     8701 ggtccccggg ccgcagttct ctcacgatgt cccggaactc tttcgttggt tcgtacgccg
     8761 cgcagtccag atttcctttc gatgtggtaa cctggaagat cacgtgacct ccggtcacgg
     8821 tgcgcggagc ctcgctcacg gtggccaaga catcgtacga acggtccggc aggctcggtt
     8881 caccgcggat gagatggtcg tcggtgccct ggttgctcag gaacattatc cagcgggcgg
     8941 gcggttccga ccgcaggctg aaaacggcgg acatgagctc cttggggtcg tccccccgga
     9001 ccccgaagag caccgggcag ggcgtgtgcg gcgatatggc ccttcttccg atgtggtggt
     9061 cgaagttgtt gaaggtgctc gggtatcgga ggtccatctc cttcaccgat aggtcgtcaa
     9121 gatagcgagg ggtgccccac ctttccttct cccggtaggt gatgatctcg tacgttgagt
     9181 cacgaggctt ccaggccatg gccgcggacg ctccgattat gccgcgaccg ccttcccagc
     9241 ccaccatgtc ggcgccgatg cgctgcagtt cccgcagggt gtcctccttc ctgactatgc
     9301 tgcgcaccgc gctccaatac aggctctgcg ccggcttcct ctcgctgacg accagcccgg
     9361 ggctggcccc ctccgtggtc cgggaccatt tggcgacgat tctttcggcc acgtccagaa
     9421 cgaggacccg gtcggcctcc tcgtacatcc tcttgtagct gtagacaggg gcgccatcca
     9481 gctcccccac catatcgcat tctccgcggc ctacgccgaa gcggaggcag agcgccccgt
     9541 tcccccgggt cttccagggc acggcggggt tcagccttac caggcgcggc aggccgatca
     9601 gatcgtacac cccgagggcc tttatcatct cggtggcgag gaaggtggtg cacatcgatt
     9661 ccagggaatc ggtgtcgtcg aaggctacga acattatgtt tcggcgagcg ggttggggct
     9721 taaagtaact ttcactaagg tgaaatcttg aatactagga ttttcgattt ccctccctat
     9781 gtccaagccg atgaacgtgg aacggggtct ggagctttcg gtcctgataa cagttctcgg
     9841 agctgtcctt ctgttcctgg gaatatcgga tgctctggat tgggtcatag acctgcgggg
     9901 ctggggattt tacaccgggg cgatcggggt catttctttg atcgtcgggg ttatctgggc
     9961 aatatccatc gttcagcgca tgcgccggtt tgatgttctg atcgaggaga agagcaaggc
    10021 ggtcttcgtt cgaaatcttg atgatatcga atatacagca tggcgccttc cttcgaaata
    10081 tgatgtgcgt cttgatgaga agaagaggaa gatgggagtg aagtagaggg ggaccccatc
    10141 gtttcatatg gaacgaaatt tcgtagcgtt cgtccctgga agaccatttt ttcttcaagg
    10201 acctcgtttt ttaatagttt ataacaatat ataatataat aaataaaaat cgattatcta
    10261 tctaacgtat ctggaatcga ccgcacttga aacgtccttt attccaggta acgaatataa
    10321 tctatccatt accttctcca gatcatcctc atgacatctg aacaccactt ctaccagatt
    10381 cgaatagacc accgactcga cgaaatgatc gtcatagagc ctggagatct ccgtagctga
    10441 gctcttacta ttagcagctt taaaactcac cactaccgaa ggacggaaat aggattgcat
    10501 aaaatccatc agttcgtcaa taccatatcc agttacggcc gagacaccga tgaccgataa
    10561 cggatcaagg atctcgttca cggcagaaat catttccgtt agaccatctg ggtcttggtc
    10621 catcttgttc aagaccacca ccatcttgcc cttcatctga ccttttccaa gtatctcttg
    10681 cactgcgacc atcttggagc ttactttgaa cagcggttct gaggaatcca ccaccagtat
    10741 caccaggtca gcggtgaaga catcctgcaa ggtgttccgg aacgactcta ccatgaaatg
    10801 gggaaggtcc ttcagaaaac cgaccgtatc ggtcagcaat atctttgagg aaccgacccg
    10861 tctggtggtc gttcccagcg ttgagaacat cctgtcggcc accaaaacct cctcaccggt
    10921 cagacgtctc atcagggagg actttccagc attggtatat ccggccaggc acaccgtccg
    10981 gaaacctttg aaatggcgaa ccccgcgccg aaggtccccg tccctagcca aggaccgcag
    11041 ctcctcatcg atctgggcta tccggcgccg gattatatta tagtagacgt caacctgata
    11101 ctctccgccc cccaggaacc cagggtgctc gccggccttg gcgctgtgca cccattccct
    11161 catcaacggc acctggtaat tcaaacgagc aagctccacc tgcagcttcg attcccgtcc
    11221 ttccgctctg ctagtgaaga tatcgaggac cacggcgatc cggtccaaac attcgacctt
    11281 caacccgttc tccaagttga aatgctggga aggctttagt tctccgttta tgaccaccac
    11341 gtcaacaggt ctttccagaa gcagctcctt aagttcgttg aaccttcctt tcccgaggta
    11401 gtgagatctg tcgggcctag ctcgccgctg catgacgacg tacaagatct ctatgtccgc
    11461 cgaacggcag agctcttcga tctccgccgt ttcccggtcc agacttatca gcgccccctt
    11521 cttcaatgct cgtgaccctc gcacctccat ccgctcggtc tcatttacct tatttggtaa
    11581 cagaccctga tggggttcca tatgaaacaa aggggtgggg gtgtcacctg gagcggaagc
    11641 atcgcccccg cttacttcca cgggcgggga taaaagtaag gttctagtaa tcaggagcgt
    11701 aatgtcctgc tccttacttc atagagcctt cttccaacag ggaaggccga gaggggcatc
    11761 atggaaacca acgtattcac gcagcacatg gaccgcagac agatcttcaa gaagaacaac
    11821 cgggagatcc tgcgcccctc gtacataccg gacgtactgc cgcaccgcca ggaggagata
    11881 aactccctgg cctcggttct ggtgaccgct ttgaaaggcg agcgccccag caacatcctc
    11941 atcttcggga agaccgggac gggaaagacc gcctgcgtca agttcatcgg caacgagatc
    12001 aagaaggccg ggggcgagga ggcgacggtc accttcatct acatgaactg cgaggtggtg
    12061 gacacctcct acggcgtcct gcagaacatc gggaaccaat tcgtcaagga cttcgatcag
    12121 cgcataccgt tcaccgggct cagcataatg caggtctaca acatgctccg ggacaaactg
    12181 gacgagcaga accacgtcat catcatcgcc ctggacgaga tagacaagct ggtgtacaag
    12241 agcggggacg acgtgctata tcacctgtcc aagataaacg acgaccttaa gaaagcacgg
    12301 gtgtccgtca tcggcatatc caacgacctg ctgttcaccg agatgctgga cccccgcgtc
    12361 cggtcccgaa tggagggcga gaagatggtc ttcccgccct acaacgccga ccagttgaag
    12421 gacatcctgc ggcaacgctc gtcgctggcg ttcgatgagg gtgttctcga ggaggccgtg
    12481 ataccgttgt gcgccgcctt ggccgcccag gagcacgggg acgcccggcg cgccctggac
    12541 cttctacgca tcgccggtga gatcgcggaa agggagaatt cggagaaggt gcaggagctt
    12601 cacgttctaa aggccaagaa caagatggag ctggacaccg tgagcgaggc gattcggacg
    12661 ctaccgacgc aatccaagat ggtactgatg tgcatcgtca ccaacgtgga acgcggaacg
    12721 gagaagctga ccaccggtga tgtttacgag acgtacaagg aaatgtcccg cattctgggg
    12781 atgggtccgt tgacccagag gaggatcacc gacctcatct ccgagttgga catgatgggc
    12841 atcatccacg ctcgagttcg ttcgttcggc cgcggaggcc ggaccaagga gatcgatctc
    12901 agcgttccgt tggcggagac caagaaggtg ctggaggagg acgatgtgtt cgtcagcctg
    12961 aagcactaca agcagaggaa ccagaccacc ttgatgtgat cacttcttcc ggcgcatcct
    13021 ttccctgatc ctggcccaga cgtctatgcc gcgtctctgc aggaccaggc cggtcatgtc
    13081 catggcgagt gggaccacta tgaccaacgc cagcacgatc agtaaggcgt tcttgctgtt
    13141 gtccggggtg ttggccggca tattgccgtt cacccacagt tttatcaatc ctagccaggg
    13201 aagctccgcc ttggcctcgc cgattatcca ttcgtccatc accggctcgc ggcagacggc
    13261 ggcaccgggg tattggtcgt aaaatccgat gtaggtccca cctatctcac gcacattgtg
    13321 gtcgcccatg gttattatgc cgtcgtggtc cagttcgtgg tcggcataga agcttagcag
    13381 ttccaagaga tccacccgca gtacggccga acgataaccg acgtcgtaca cctccacgac
    13441 atcggtgagg ttccaccatc ggccatcctc cagaggtcca ttgccccact tttccgccgg
    13501 cagaccggcc agagagggga tgtcgaagct gcttgacgtg gaattatact ccaggcgcag
    13561 catggcccga tgtattatgg gggtgtagtc cgaccatccg taacgctcgt aaactatgac
    13621 gtcaccgtaa tccccgaagg tgcgatgccc gtccggatag ctttccacat acgttcgaac
    13681 gtcggaaccg tccgagctct gtacgatcac caggtccccg gtgtcgatcg ttccgataaa
    13741 actgcggtca tcgctgtgct gcatgctctc cgattccacg acgtaaaccg gtggccacat
    13801 tccggcgtat atgaaaacgg ccaataacag tatggccatg gtcaggagcc ctccgaccag
    13861 caccttgtac tgcctcacca cgttccacag cttaccagac gcgtcggaca acggtccact
    13921 taaccaactt acctgtaatt aagagtgccg aacaaggaat taatatggcc gtaccgaatg
    13981 ccggggggat gagcaacagg ccggacaacg acacctactt catgcgcatg gccgagctgg
    14041 tggccacccg atccacgtgc ctgcgtcgcc aggtcggggc ggtcatagta aaggagaaga
    14101 gggtgctcac caccggatac aacggagccc ctcgcggtct gaagcattgc gaggaggtgg
    14161 gctgcgtgcg ccagcagaac aacgtcgaat cgggaacgag gcacgagctg tgccggggcg
    14221 tgcacgccga gcagaacgcg gtcatccagg gcgcgtactt tggcgccagc atcaaagggg
    14281 cgaccgttta caccaccaac ttcccctgcg tcctttgctc aaagataatg cttaacgccg
    14341 ggatcgagga gatagtctat ctagacacgt acgtggacga gctctccaaa cagatgttgg
    14401 aagaggcggg gatcaaggta aggcgttacg aaagaccgct attataatta caaaatatat
    14461 aattatatta tcatttattt tagcgcggtc gattcctatg ctaatttttg acattccatt
    14521 gctggcctat tattgaatat tcctctagag aatcggtatt tttgataaac gatgcatatt
    14581 ttatcagcca atcgggcctc agttagcaaa ttgtttatat actttgatta aattcccaga
    14641 acaaccttcc ggggagacat ctgtgaacag atctgatatt cttcttcaag ttaaggatgc
    14701 cgagtccaag gcgcaacaga tcgtcaagga ggcggaagaa aagcagaggt ccaccgtgac
    14761 ttccgctcgc cgcgaggccg ccgcccgcgt taacgaagcc gacgagaagc ttagggccga
    14821 gtacgattcc aggttcgcca aggagcgcga gagcatcgcc tccgagaagc aggcctacct
    14881 gaacaaggga aaggaagagg ccgctgccgt caaggccaag gccgagggca aggtccccaa
    14941 cgtcataacc catctgatgc aaagcttcga gaggacttta gatgttgctg ccaaaacaaa
    15001 tgactagggt cctaatcgta ggatcccgag gagcattgaa ggacaccatc gaggtgctct
    15061 annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ncaccttcgc catggacgcc
    15181 tgggtaccga cctcggaaat gccgacggtg gagaaggcca taaacgaaaa gctagccggt
    15241 aaggtgcacg tcgagtcact ggaggtcatg tcccgccgcg aggcgcacgg tcaccacgac
    15301 gccgagcagc acgatgcccc ggtcgaggag atcccctcca agaccgagaa cggcaagacc
    15361 gtcagcaagt tcgagttcat ggcccggatg ctgtccaccc ccaagtaccg ggagatagac
    15421 cccgccgtca ccatgatgat caccatcccc atattcttcg gcctgatggt cggggacatc
    15481 ggttacggaa ttccattcat gatattgggc ctgatcgggc tcaagaagtg cgtctccgac
    15541 gagtggagga ccatttccac cctgctgttc ttcggcggta tctgggcgtc catcttcggc
    15601 ctgttcatgt tcggggaggc ctatggtatc cacttcgcgg aacaggctca tgacatgagc
    15661 tggtcctcgt tgctgggcgt acatcttccg catgagatag ccatcggcgg gttcgagatc
    15721 ccgctgggca tatacagcaa gctccacaac gtcaaggaga tcctgtacat gaccctgtgg
    15781 atcggcatcg cccacatctt catcgggttc tgcattggct tctacaacaa gtccataagg
    15841 ttcggcttca agcacgcggt catagagaag atcagctggc tgatgatact ggtgggcggc
    15901 gccctactgc tgctcttcct ggtggacgcc atgatccgcg gtctgaccgt tgagctgacc
    15961 gacattagga tgctgatcgc cttgccgctc atcgtgatcg gcatattgat ggcctacaag
    16021 ggtgaaggct ccggggccat cttagagctg cccgggttga tgggaaacat catatcctac
    16081 acccgtctgg ccgccatagg catgtccaag gccggtctgg ccttggcctt caataccatc
    16141 gctttcgagg tgatgtgggg gcacgacttc cacgtcatgg gctcgaacag cggggacacg
    16201 atcatgctca tcgccgcatt ggcaatattc ctgatagggc acctgaccat attcgtgctg
    16261 gccataatat cggctggatt gcacagcctc aggttgcact acgtagagtt cttcatgaag
    16321 ttctacgagg gcggcggtgt ggagttcaaa cccttaaaag tgattcgtaa gtatacgaca
    16381 gataagaacg gagtaagtga gtaaaatggc agatgcaggt ttgatagcaa tcggtgctgg
    16441 aattgcagtt ggtattaccg gtttggcctc cgcatgggcg gagaaggaga tcggttccgc
    16501 cgctataggc gccatggccg agaacgagaa actcttcggt aagggtctta tcctgaccgt
    16561 tatcccggaa accatcgtaa tcttcggtat ggtcgtagcg attctgctct ggctcaacat
    16621 gtgaacggtg cggaacgcac gggaacgtaa aaaggaaaag aggccgacgc atggcattgg
    16681 atgaagtgat tagcagcgtt acggagagcg cccaggctag ggccaaggag ctttccgccg
    16741 aggcggataa ggagaaggcc gctatcctca ggcaggctga cgataagatc gccgccaaga
    16801 ggctggccca gcagaaagag ctggaggtct ccataaaacg cctcaaacaa caagatatat
    16861 ccagtgccga gcttgaagcg aagaggatcg tcctgaacgc caagaaggac gttatggaca
    16921 gatctttcca ggaggccctc agctcactac tcaacatgga cgaaggcaac cggggcagga
    16981 tgtaccgcaa gatactggag ggcggcaaga ccgtcatcca gtcccccaag gtcttctgcc
    17041 cgcggggcga gtccaagttg ataagtggcg ttgctggctt ggggaaggta gaggaggccg
    17101 acatggaggc tgggctggtt ctagaggacg cctcgggcaa cgtgcggttg gactaccggt
    17161 tccgggtcat cttggagagt gtttgggaca aggaactgaa gaacgtctca aacatattgt
    17221 tcgggtgaaa ggatgttgtc tatctggggt agcaagggaa actatgccta cgtgaccgct
    17281 agggtcaaag cgaagaagag cctgctcatc tccaaggaca actaccccaa gcttatgctt
    17341 atggacctga acgagatcgg ccgcttcctt ggtgagaccc agtaccaggt cgagatgacc
    17401 gagctggcca ccaagtatga cggcgtcaat ctcatcgagc tcggcaccag caagaacttg
    17461 gccagggtgt tcactgatat cctgaactac agcaaggggg acctccgcga tatgctggag
    17521 cgctacctga tgcgctggga catctggaac atcaagacca tattgcgagg gaagtattac
    17581 ggggcctcca cggaggatat tctggaggat atagtggccg ccggaaagta cgacgagggc
    17641 ttcatcaaca ttttgatctc cctcgaggac gttgaggcgg tgctcaagga actgaagagc
    17701 aaggaggggc tggtcatccc tgacgaggtc gtcgaggaat accaagagac caagaccctg
    17761 gccccgatag aggattacct ggacaggctg tactacgacg aagttctagc ctgtgtgaag
    17821 tgccgggata aggccgaaag gctgttcaag cagttcctgc gcaaggaggt ggacgtcacc
    17881 aacctgatga ccctcctgaa gctgaagaag gaagggctct ccccggaaca cccggagaag
    17941 tacttcatcg acggtggcga agagctgcag atcaagacgt tggtggagct gagcaaggcg
    18001 gagaacgtag agcgccttgg cagcgaactg accaagtttt cattctacgc ggacattaag
    18061 gacgctctgg aggagttcaa gcagaccggc tcgctgagca cggtcagcct ggccatgcag
    18121 cgccatctcc tgcggagctc ggagaagttc tcgcacatct atccgttgtc ggtactgccc
    18181 attatggact tcatgctccg caagaagcag gaagtcgaca acatcaggat aatcgcgaga
    18241 tgcaaggaga gcgatctggg accggaccag ataaagaagc tgttggtgat gtgatggaca
    18301 ttgcggtatt aggcagcgac gagttcgtgt tgggattccg gctgggcggc gtgaagcgca
    18361 tttacaccgc caaaaccaac gattacgagg ccaaggcgct ggagctcata gctgacagca
    18421 gcattggcgt gctagcgatc gattcctccg acctggagct cttgagcccc aacgcgagga
    18481 ggaaggtaac tgagaacatc gcccccgtcg tggtgatggt gggcaaggcc gagagcgacc
    18541 tcagggagaa ggtcaagcgg gccatcggtg ttgatctgta caaaactaat tgaggggttt
    18601 gacatgggaa aggaaggcgt gatctataga gttgcagggc ctgtcgttac ggcggtcggc
    18661 atttcgccta ggatgtacga cgttatcctg gtgggcaagg aacagctcat gggagaggtc
    18721 atcaagatcg tgggcgagaa gaccatcatt caggtgtatg aggatacctc aggcgtgcga
    18781 ccgggagaga aggtcgtcga taccgagcag cccctcgtgg ccgagctagg acccggcctg
    18841 ttgtctagcg tttacgacgg tatccagagg ccgttgcccg tcctgatgga aaagatgggc
    18901 aacttcatcg agaggggagt ttccgcccct ggtctggacc ataacctgaa atggcccttc
    18961 acccccgtgg tgaagcaggg cgacaaggtt accgagggac agatcatcgg taccgttcct
    19021 gaacgcgcta tcacccacaa ggtcatggtg cccccgggca tcagcggcac cgtggacatg
    19081 atcaagtccg gcgagttcac cgttgacgag atcgtggccg tgatcgacgg aaaggaggtc
    19141 agaatgatgc agaagtggcc cgtccgccgt ggccggccct tcgccaagaa gacggcgcct
    19201 gacgagccgc tcataaccgg gcagagggtc tgcgacacgt tcttccccct taccaagggc
    19261 gggacggccg ccatccccgg cggtttcgga accggaaaga cggttaccca gcagcagctg
    19321 gccaagtggt ccgacgccga gatagtcgtt tatatcggtt gcggcgagcg cggcaacgag
    19381 atgaccgaag tgcttacgtc cttcccggag ctgaaggacc ccaagaccgg caagcccctg
    19441 atgaacagga cggttcttat cgccaacacc tctaacatgc cagtggcggc ccgtgaagcg
    19501 tccgtctaca ccggcatgac catcgccgag tacttccgtg acatgggact gaacgtctca
    19561 cttatggccg actcgacctc tagatgggcc gaggccatga gggagatatc gtcccgtctt
    19621 gaagagatgc ccggtgagga aggttacccc gcgtacctgt ccgctcgtct gtcggaattc
    19681 tacgagaggg ctggcagcgt tatcgccctg tcgggaaaaa ccggctccat ctccgtcgtc
    19741 ggcgccgttt cgccgccggg cggtgacctc agcgagccgg tcacgcagaa caccctgcgt
    19801 atcgtccgtg tcttctgggc cctcgacacc aagttgagag agaggaggca cttcccggcc
    19861 atcaactggc ttacttcgta ctctctgtac tccggccagc tggacggctg gtacaagaag
    19921 aacgtggccg aggacttccc cgagctgcgc aactgggcgg tcggacttct gcagaaggag
    19981 gccgagcttc aggagatcgt gcagctggtc ggttccgacg ccctgccgga cgagcagaag
    20041 ctgaccctgg agatcaccag gatgatccgt gagatcttcc tgcagcagaa cgcctaccac
    20101 cccgtggaca catactcccc gatgggcagg cagtacacct acctgaagct gatcaaccgg
    20161 ttctccacct acgcctccaa ggccgtggag aacgaggtct ccgtggaagc catcgccaac
    20221 atggccctgc gcaaccgcct ggccaagtcc aagttcgagg acaacatcga gggcgagctg
    20281 aaggccatcg ccgagaccat ggagaaggag ttcgaagccc tgggaggtaa gtaaatgaca
    20341 tccaaggaat accgttccat cacccagatc gccgggccgc tnnnnnnnnn nnnnnnnnnn
    20401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20461 nnnnnnnnnn nnnnnnnnnn ntgggcgagg gacaacccgt ccgagttcat tcaaacggga
    20521 atttcaacca tcgacgggat gaacaccctc gtccgtggtc agaagcttcc gatcttctcc
    20581 gcctccggtc tcccgcacaa cgagatcgcc ctacagatcg ccaggcaggc caaggttctc
    20641 gggggttccg aggacttcgc cgtggtgttc gccgccatgg gcatcaccaa cgaggaagcg
    20701 cagtacttca tgaaggactt cgagaggacc ggcgccctga agcgcgccgt ggtcttcctg
    20761 aacctggcgg acgacccggc catcgagagg atcatcaccc cgaagctggc gctgaccacc
    20821 gccgagtatc tcgccttcac gttggacatg catgtgctgg tcatcctgac cgacctgacg
    20881 aactactgcg aggcgctacg ccagatcggc gccgcccgtg aggaagttcc cggtcgccgc
    20941 ggttaccccg gctacatgta caccgacctc gctggtatct acgagcgcgc cgggaggatc
    21001 aagggcaaga agggaagcat cacccagatc cccatcctgt ccatgcctgg tgaggatatc
    21061 acccacccca tacccgacct taccggttac atcaccgaag gccagatcgt ggccaagagg
    21121 gaactgctcc gggccggcat atacccgccc atcgacgtcg gttcctccct atccaggttg
    21181 atgaacgaag gtatcggtcc tggacgaacg agggatgacc acaaggccgt ctccgaccag
    21241 tgctacgccg cctacgccga gggacgtgac ctacgcggac tggtggccat cgtcggcaag
    21301 gaagcattgt ccgagaggga ccgcaagttc ctggagttcg ccgacgactt cgagaagcgc
    21361 atcgtgcagc agggccgcga cgaggaccgc accatcgaag gaaccctcga cctgatgtgg
    21421 gagatcctgg cctcactgga cgagaggcag ctgaccagga tagaccgcaa gtacatcgag
    21481 aagtaccacc cgaagtaccg caagaaggat tgagatgtca accgccgacg tcaaaccgac
    21541 ccgctccgaa ctactggaga tcaagaagaa gatcaagctg accaagtccg gctacaagat
    21601 cctcaagatg aagcgggacg gtctgatcat ggagttcttc aagatcctgg cgcaggccaa
    21661 ggacatccgg gacaaggtca accatgatta cgcggaagcg atgcgcagca tcgccatcgc
    21721 caaggcggtg gacggcgcga tagcggtgca gagcgccgcc ttcgccctga agacccatcc
    21781 tgagctttcc ctccgatcga agaacatcat gggcatcgtg gttccggaaa tagaggccaa
    21841 ctccatccga acgccgatgg accagcgcgg ttacggcgtc atcggaacgt ccgtctacat
    21901 cgacgaggcg gccaaggcct tcgagaacct ggtcgaaacg gtgatcgagg ccgcggagat
    21961 cgagaccacc atgaagaaga tcctggatga ggtggagaag accaagcgcc gcgtcaacgc
    22021 cctggagttc aaggtcatac ccgagctgca ggaatccgag gccttcatcc gcctccgcct
    22081 ggaggagatg gagagggaga acaccttccg gctgaagcgc gtcaagcaga aggcggaagc
    22141 gcgcggatga tgctcgaaa
//
LOCUS       DAOPZI010000025        22030 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_2404_length_22030_cov_8.939340, whole genome shotgun sequence.
ACCESSION   DAOPZI010000025 DAOPZI010000000
VERSION     DAOPZI010000025.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 22030)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 22030)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22030
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2404_length_22030_cov_8.939340"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            254..538
                     /locus_tag="PKM11_05895"
     CDS             254..538
                     /locus_tag="PKM11_05895"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48071.1"
                     /translation="MGVRYGLFNHTKKEFVVPEKIPVDAADPTTYPFANFISYLMMES
                     WRYDHVAIMDDSKDFDCQRMFGSQYKDRSGELWNEFIMIMGWQFKDLRSI"
     gene            complement(542..1015)
                     /locus_tag="PKM11_05900"
     CDS             complement(542..1015)
                     /locus_tag="PKM11_05900"
                     /inference="COORDINATES: protein motif:HMM:NF024812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX48072.1"
                     /translation="MVEVRLVPMNKKEFEAMKAVGVKRYADENVKVGYWKPGEALQRS
                     ETVHANLLPDGLRTEGHHFYKALDAGTDERVGQLWLRVEPGEDRKGFIYDVFIDEDKR
                     GKGYGRAMMLAIETKAKRMKIDSLALHVFAYNDAARHLYETLGYEVKSLNMMKVL"
     gene            complement(1115..1324)
                     /locus_tag="PKM11_05905"
     CDS             complement(1115..1324)
                     /locus_tag="PKM11_05905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48073.1"
                     /translation="MVTVELTFGVPDKVAEEVKKKFANEKDALRVTKANPAFPPYYSV
                     GDPRAKPEEITVDGKKYWVYRCFQG"
     gene            complement(1539..1748)
                     /locus_tag="PKM11_05910"
     CDS             complement(1539..1748)
                     /locus_tag="PKM11_05910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48074.1"
                     /translation="MVTVELTFGVPDKVAEEVKKKFPNETDALRVTKANPAFPPYYSV
                     GDPRAKPEKLKVDGKEYWVYRCRKA"
     gene            complement(1892..2179)
                     /locus_tag="PKM11_05915"
     CDS             complement(1892..2179)
                     /locus_tag="PKM11_05915"
                     /inference="COORDINATES: protein motif:HMM:NF013629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HNX48075.1"
                     /translation="MEIEEVAKALSSDTRLKILRLLADGEASAVHVYKLYNERFAERR
                     ERATVYRELEVLYKSNFLVKTYKEESKEIVYRLSARSINIDLVAQTASAGP"
     gene            2277..3119
                     /locus_tag="PKM11_05920"
     CDS             2277..3119
                     /locus_tag="PKM11_05920"
                     /inference="COORDINATES: protein motif:HMM:NF024247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX48076.1"
                     /translation="MGRLTMVYVRAIKGGFRYRFSLAKLTRWPLLGRMMDRTFFDGDD
                     IYVLPKESSLKVRDIPLDLAAPEREDTVLPSEVIRHFIERSRYHFVMDYCICRTSAHC
                     EDYPRELGCLFLGKAVLNIDPRLGHLVSKEEALAHLDRCERAGLVHLIGRNKIDSLWT
                     SGKPKEDLMTICNCCPCCCLWKMLPQLDPAISVKMKRLPGVRLSVDEGKCTGCGLCVE
                     GCYVNAITLREGKACIDQEMCKGCARCAHVCPEKAITLHLEDMEFLERTVSILTPLVD
                     VTKE"
     gene            3265..3792
                     /locus_tag="PKM11_05925"
     CDS             3265..3792
                     /locus_tag="PKM11_05925"
                     /inference="COORDINATES: protein motif:HMM:NF016705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HNX48077.1"
                     /translation="MVRSVTYEVVKHLGDAELRRYGDLVLATVYDMDDDEAFSLLFQY
                     IGGNNDKESKLPMTAPVVSRTGELAGHDSEAMMAFVLPSDVTFEEAPKPADPRVAIEL
                     KKGGLFAVMRFRGRAGGVDVQGRTEELRTELKEADYVMDGRPFLMRYNSPFTPGFMRH
                     NEIAARVVPGPEKRE"
     gene            complement(3793..4317)
                     /locus_tag="PKM11_05930"
     CDS             complement(3793..4317)
                     /locus_tag="PKM11_05930"
                     /inference="COORDINATES: protein motif:HMM:NF039358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6141 family protein"
                     /protein_id="HNX48078.1"
                     /translation="MPDEYEHFHEVQYFRTWWYLLLTLIPTGVVWWGAIQQLLLDVPW
                     GNNPGPDGFLWFLLVVIGVLLPAFMLSINMRTTVTDTVNIFYFPLINKPKRIFKEEIV
                     TYAVVRYSPISEYGGWGIKGTSGHRAYNVSGNRGVRITYANGNTVLIGSQKPELLYTA
                     ITAMIKTGSARLKA"
     gene            4404..4796
                     /gene="msrB"
                     /locus_tag="PKM11_05935"
     CDS             4404..4796
                     /gene="msrB"
                     /locus_tag="PKM11_05935"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HNX48079.1"
                     /translation="MGRRVERSDEEWKRELDTEQYRVLRRKGTEAPFTGKHYKTREPG
                     TYVCAGCGKELFVSEDKFDSGCGWPSFVKPLEGVEEQRDLSHGMDRTEVLCPDCGGHL
                     GHVFEDGPKPTGLRYCINSASLKFKPRK"
     gene            4807..5883
                     /gene="corA"
                     /locus_tag="PKM11_05940"
     CDS             4807..5883
                     /gene="corA"
                     /locus_tag="PKM11_05940"
                     /inference="COORDINATES: protein motif:HMM:TIGR00383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006824 - cobalt ion transport [Evidence
                     IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HNX48080.1"
                     /translation="MSGNRFMKKHHSKKTGMPPGSVIYVGDGSPSPTEVSVIDYTEAD
                     VLEKKGITFDECMMMRDNPSITWINFSGLADVEQIKKVGDIFGLHPLVMEDILHMGQR
                     PKLELYDKYVYLVVKMIYRGDNGKEVTYEQLSIVMGKNYVLTFQEREGDVFNSIRERV
                     KGNKGRLRKSGADYLVYSLLDAVVDNYFPALEKIGDLVEDIEERLSDNPEQDVLSDIY
                     RLKREVLFLRKSIWPIREVVAAMMRQDIEIVSPNTNTYLRDVYDHSIQVMDVVETYTD
                     MLSELTDVYMSTVSNRMNEIMKTLTIIATIFIPLTFIVGLYGMNFKYMPELTNELAYP
                     VVLVGMAIVSGIMLVYFRRKGWLG"
     gene            5885..6913
                     /locus_tag="PKM11_05945"
     CDS             5885..6913
                     /locus_tag="PKM11_05945"
                     /inference="COORDINATES: protein motif:HMM:NF013543.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HNX48081.1"
                     /translation="MDALTLVALAGIALSLLFAFTNGYNDAGADVATIVSSGAASVKG
                     ALLMAATNNFIGALIGGSAVVLTMQGVLTNEIVGSVGLAMFSAVAAANLWNVVTWYYG
                     IPSSSTHALIGGLIGVGIAFHGLSGVNWGWNELLTGQLTGVAKVLTFLLASVLLGFGG
                     SFILMKLARLFLRGASVDANRPMKRLQWLTTGVQTLAHGANDAQKQMALVALLLVAMG
                     SSTLEVPLWVRVACAAAMALGTLGGGYRIMRTVGRKIFKIRPVHALVAQTNSSLTVIF
                     ATLLGAPVSSTQVVTAGVMGVGSAENHRLVHWRVGKDLVVSWFMTIPAATLLSVVIVI
                     VMRALLEV"
     gene            6915..7541
                     /locus_tag="PKM11_05950"
     CDS             6915..7541
                     /locus_tag="PKM11_05950"
                     /inference="COORDINATES: protein motif:HMM:NF013982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 family protein"
                     /protein_id="HNX48082.1"
                     /translation="MEEKKGLLDGLFPPKYDFNAMLVGQAEDTAKGVELLLSALQGER
                     DHHLSALIELDRRTDEFRHDMERKLGEAFSTPFDRQDIYTMSRQLELVMNFARTTLLE
                     METFGVEPDRCMLKMAEHLLVGTREVVEGVKALGKGLERTDDLIKKMREEEQSIEETY
                     VAGMQKVFLLPDHMMVLKKREIYHHLKDAGRALSATADILHRAAFGMG"
     gene            complement(7538..8485)
                     /locus_tag="PKM11_05955"
     CDS             complement(7538..8485)
                     /locus_tag="PKM11_05955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EF-Tu/IF-2/RF-3 family GTPase"
                     /protein_id="HNX48083.1"
                     /translation="MGNLNVAAVGALGYAKDLGKKGTVSDITIYDMKKGQDTVSILEP
                     AKYPDRINSLYFCVNLAEMALVVVDEINAAFGETLLMLDCANVKRGVFILRNYLTPDR
                     IAPLIKDTVLMNYIYMPDDLIQLREYLLDEASKIKPHGEGKGVIPIDHHFNVKGVGTV
                     VLGYVAKGVVNRHDSLKVLPTDRTALVRSIQKHDDDFDVAYKGDRVGFALKGIEAEDL
                     DRGYVLTNDPEMKVISELNVKLNLVKYWQSPIKEGMVMHLGHWMQFLPCRVTSVSGEA
                     RTPQVTLTLEKPLIYGPGDRAVMHYLEGGKLRIVGTIDL"
     gene            8568..10058
                     /gene="pap"
                     /locus_tag="PKM11_05960"
     CDS             8568..10058
                     /gene="pap"
                     /locus_tag="PKM11_05960"
                     /inference="COORDINATES: protein motif:HMM:TIGR03708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0043751 - polyphosphate:AMP
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006797 - polyphosphate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate:AMP phosphotransferase"
                     /protein_id="HNX48084.1"
                     /translation="MFEHVDPGKHLDQKEYDKVVTELKERLGELQRHARDAGMPIIVV
                     FEGWDTVGLSEVVNKFILPLDPRGFLVHPITAPRYDEKLRPFLWRFMVRIPARGRIAV
                     FDRSWYFRSLARAERREEAARLAWREIAEFEEMLSDDGYLIMKFFLHIGKKEHKKRLD
                     NYKDKDLDQCAISTSEVDFFRKYEKMVPLIEEMIESTDREYAPWTIVEAEDQKFASAK
                     ILTTAVRMLEYGLSKMESKNQIHMDSNPLIKGGQMFNSSRGSVDLSKKLSQEEYKVKL
                     EKLQNRIKVLQCELNRLKIPTIVVFEGWDAAGKGGAIQRLTAELNPRGYEVVPVGVPT
                     ADEKEHHYLWRFYQKLPPAGHVRIFDRSWYGRVLVERVEGFCSTEEWKRAYKEINLFE
                     EMLVDNGGVLVKIWLEIDKDEQLKRFEERDKDPMKQWKITEDDWRNREKWDFYGRAVD
                     EMLFRTSTKLAPWTIVESNDKFYSRVKTLQTIVQAMESKLPKKDSK"
     gene            10102..11529
                     /locus_tag="PKM11_05965"
     CDS             10102..11529
                     /locus_tag="PKM11_05965"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HNX48085.1"
                     /translation="MSSFQEFGLRDEIMKAIERMGFVEPTPVQVATIPLTMKGKDVIA
                     QAQTGTGKTAAFGIPILESLTKGVKPFSLILVPTRELGSQVSDELKKLAFFMDDVRVL
                     PVYGGKSIDEQVDAFRKGVDIVVGTPGRVIDHLHRGTLALNEIEVLVLDEADRMLDMG
                     FIEDIEYIVSKVKKQRQTMLFSATIPETIKEIAAKHMVDPETIMIGEEQIVLPTTKQV
                     YFNIERKNKIWALCRVLDAYKPKAIVFVQTKVMVDILAKRLDSYGYRVGELHGDLTQA
                     RREKVLKEFREGKTAVLIATDVAARGLDIEGVTHVINYDIPEDPEVYVHRIGRTGRAG
                     KEGIAITFITSKEVHLLKKINEFGVTEIAKEEVPESGRKDVIRKVMDFEDQADLFGMV
                     LFKVVAGENEPVERADLLALLNRKMRIPELAIGNINVLKDRTEFEVHKDSAKIVLMEL
                     KTLRVGDKKLKVEIVHRELPPVSMQ"
     gene            complement(11580..12884)
                     /locus_tag="PKM11_05970"
     CDS             complement(11580..12884)
                     /locus_tag="PKM11_05970"
                     /inference="COORDINATES: protein motif:HMM:NF024091.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX48086.1"
                     /translation="MSSLSKIIRKEVKELLTPATLIPIIIIAVLFGSLGGVFGGVEEQ
                     LEEPPMIAVINQDGGSLSLVAMAVFNATSDIVYNGTDVQEALNVLDEKGGVSLFVIPA
                     NFTSNIENDTQGTIEIFWIMKGAGIMDSVPGAAADANLMYVDQAISATLINHNMSDNA
                     SLILDPTQYYETTLFKGKEMTGISPITISSVMSSQSFVMPLIVMMVIIYAGSIVISSM
                     GSEKENKTLETLLTMPVSRTSIVFGKLIGAALVGLLMAVIYMFGMSYYFDSLMGSSSI
                     DLAEFGLTLSIVDYILVGMSLFASLVFALALCMILGIFTKNYKAAQTMTMPVTFLAMI
                     PMFVTMFTDVDTLPMVAKVLVLAIPFSHPMIAMRSLMFDDYSLVLGGIAYTAAVALLA
                     MFVAVTLFKKDILLTGKVSNSDKKSKIPLVALLQTISRKRKK"
     gene            complement(12881..13600)
                     /locus_tag="PKM11_05975"
     CDS             complement(12881..13600)
                     /locus_tag="PKM11_05975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX48087.1"
                     /translation="MYAVEVKDLVKRYGTFQAVKGISFHVKEGEVYGLIGPNGAGKTT
                     TLRILATLLEVTSGTIQIQGIDLRAKPEEVRRVISYLPEDAGAYKHLRGREYLKFIAQ
                     FFAEGDEAEALVARGMEIANLGERIDDKVDTYSKGMARRLLVARALMIKPKLAILDEL
                     TSGLDVLNAQEIRKTVKSFAAQGTTMLLSSHNMLEVELLCDRIALINDGMIVAEGTPA
                     ELKQRYDAQNIEEVFVKVVRK"
     gene            13713..14336
                     /locus_tag="PKM11_05980"
     CDS             13713..14336
                     /locus_tag="PKM11_05980"
                     /inference="COORDINATES: protein motif:HMM:NF017959.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HNX48088.1"
                     /translation="MDRDRLALLGASAGIIGVVAFQALFSISLLYHPDWRFGLDLMSE
                     LGTTEPYTWLFNISVMVMGALGVAFSLSLLRFLYWSLLGKLSVVMLVVGCTCLFLLGV
                     FTMKQRALHDALAWNFFVLIVIGLLVLSIPMYLYWNKARWAFAATLATVVLSLTCLIM
                     IGLGLMKHHLAEVLVVYALGAWMLAISIFMVLRLRRNDLPFTPYNDS"
     gene            complement(14314..15387)
                     /gene="hypD"
                     /locus_tag="PKM11_05985"
     CDS             complement(14314..15387)
                     /gene="hypD"
                     /locus_tag="PKM11_05985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016530 - metallochaperone activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HNX48089.1"
                     /translation="MNDLRFRDEATAKKIMSKLKEMDLELRFMHVCGTHQDTLVKFGL
                     EKMLTEVGITIGQGPGCPVCVTTTKEVVEAITLARAGVSITVFGDMMAVPTPIGSLAE
                     VKAEGADVRVVYSVEDALRMSADVERMVFMAIGFETTSPSTAYALLHDPPKNFSVLSC
                     HRLLPPALKALFAMGEVRIDGLIQPGHVATITGIDIFNEFAGPKGVPQVVTGFEPLDL
                     LMAVYMLAKQVKEGRSEVENEYPRVVRPEGNLKAREMLAKAFKAEDRAWRGFPVLPLS
                     SLEVSDDLADHNARLVYEDVLKDAPKVKEDMGGCRCGEVLRGIIRSEECPAFGKGCSP
                     KRPMGPCMVSREGSCNISYRYRE"
     gene            complement(15384..15755)
                     /locus_tag="PKM11_05990"
     CDS             complement(15384..15755)
                     /locus_tag="PKM11_05990"
                     /inference="COORDINATES: protein motif:HMM:NF013334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HNX48090.1"
                     /translation="MHEVSVMAGIVESVLKELEKHEVLRVEEVLLSLGELTFLGEEQL
                     QFAYEIITRDTPLEGSTLVIQPEETELQCLSCGYVGKADKVGEEFHMSMPSLACPRCK
                     GKVKVLKGQSCRVTSMKVVQE"
     gene            15877..16158
                     /locus_tag="PKM11_05995"
     CDS             15877..16158
                     /locus_tag="PKM11_05995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48091.1"
                     /translation="MPEEESRNEAFESIIEGKKMEAYAEHRTKEMHACALCGAIGYKK
                     RPMRPVGHKWICIDCLRSLKETLDGLDQWEAEIQLEKEMSKKIDETMRT"
     gene            complement(16163..16798)
                     /gene="nth"
                     /locus_tag="PKM11_06000"
     CDS             complement(16163..16798)
                     /gene="nth"
                     /locus_tag="PKM11_06000"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: protein motif:HMM:NF012933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HNX48092.1"
                     /translation="MDLRWLLTSMRSSINGMAFPGLIDEEDTWWEKDPFHILVATVLS
                     QRTRDLNTFHASSNLFGRFNTPQEMAAADIGELEALVRPVGFYRAKAKAIKEIARLVV
                     ENGGVPRDIDEMTKWPMVGRKTANCVMTYAFKEPAICVDTHVHRISNRLGIVDCPTPD
                     ETEMALRKVFPRTLWCEINGTMVRFGQKICLPRNPKCAQCPIKNECAYPDK"
     gene            complement(16788..18074)
                     /locus_tag="PKM11_06005"
     CDS             complement(16788..18074)
                     /locus_tag="PKM11_06005"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: protein motif:HMM:TIGR01499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HNX48093.1"
                     /translation="MSSAPLKDLEWLYSLESTGIKLGLSNTRLLLNRLGDPQNRFGIV
                     HVAGSNGKGSVSAMGASVLRSAGFRTGLYTSPHLVRFTERMTVDGKEMSEGRLAKYVS
                     EMRELATSGVFPRPLTFFEITTALAFLHFSDSGVEEAMVEVGMGGRLDATNVIHPRCC
                     VITPISVEHTTYLGDTIGKIAYEKASIIKDGVPVICSPQTPEAMRVVSWMADCKGSII
                     RSLGRDFQAECVGQDLEGVTVRLDSLGREVKLGMLGHYQCQNAAVAAEMALEVGKNID
                     ISGDSIVEGLSKARWPGRLDVVRRSPLTVLDVTHTPDGARAVASELEMFPGRPRVMVV
                     GMLKDKDARGAMAHLAPLFDRVICTSSSSPRAFSPQEMLEAVLPFNPRCQAVHGVGKA
                     MDLAEGMTGKDGFLFVSGSLYTIGEAMQHLEAAHGP"
     gene            complement(18071..18814)
                     /locus_tag="PKM11_06010"
     CDS             complement(18071..18814)
                     /locus_tag="PKM11_06010"
                     /inference="COORDINATES: protein motif:HMM:NF012936.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase-related protein"
                     /protein_id="HNX48094.1"
                     /translation="MEALTDRLREISKGRTAVLFSGGLDSTLLTVLARPFSELRLYTV
                     GYPGSHDIGAGRKGAEEIGLPWEPIVINDDMLRNAVAHLRDEVGVMDPVTISFEVPLY
                     VVCSRVAEEVLLSGQGADELFGGYARYSSLSPRELDEARKGDVQRLLSEGCPREARIT
                     QGFGKKLFCPYLGPKVIETALSIPAERLVGELGNKLPLRRIALGMGLNSAKAPKKAAQ
                     YGSGVMKAMKRLATENGSDLGTWVRELKG"
     gene            18924..19373
                     /gene="nikR"
                     /locus_tag="PKM11_06015"
     CDS             18924..19373
                     /gene="nikR"
                     /locus_tag="PKM11_06015"
                     /inference="COORDINATES: protein motif:HMM:NF001884.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016151 - nickel cation binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010045 - response to nickel cation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HNX48095.1"
                     /translation="MDNVTRIGVSLEPDLLEDFDKLIDRKGYITRSEAIRDLIRSALA
                     KEILKEDENAVVFGTITLFYSHHKGGVKERLMDIQHEFHQHILSSVHVHLDIEQCLEV
                     LIVNGTVKEVRQLSDELGSVKGVTHRTLHRTPVSLGEEAMRTHIHEQ"
     gene            19439..>20771
                     /locus_tag="PKM11_06020"
     CDS             19439..>20771
                     /locus_tag="PKM11_06020"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: protein motif:HMM:NF013311.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HNX48096.1"
                     /translation="MKRLVISEKSNAAARVATILSDGSAKRKSVRGVQVFNFERGEDE
                     FFVVGLRGHIIELDYPPEFNDWSKVDPMDLAKAQPAKRVTALNILNTLSELSAECDEV
                     IIATDFDREGELIGLETVSLLDKPPRSVKRVRFSALTKYEIEGAFKELTEPDHRLAES
                     AETRQVVDLAWGAVLTRFISLASGQMGNNFLSVGRVQSPTLTLIVDRHKEITEFVPEP
                     YWTVVARLEKDQEFSGDHIANPFKDEAKADAVRQRADCGKGKVMGMERKEKDEYPPAP
                     FNTTTMLSEANKLGLSPSLAMKIAEDLYTAGYISYPRTDNTVYPRSLGLKNILEKLKK
                     SDLGKEAAEILAQEQIRPSRGRVETTDHPPIYPTEAATKKELKGSKWTLYELVTRRFL
                     ATLAPSARSESARCDLELGGEPFRAEGYRMLSPGWRKYYPYWRVTEVLLPEL"
     assembly_gap    20772..20871
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <20872..21810
                     /locus_tag="PKM11_06025"
     CDS             <20872..21810
                     /locus_tag="PKM11_06025"
                     /inference="COORDINATES: protein motif:HMM:NF013555.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HNX48097.1"
                     /translation="TESRMTAQLEKDMDSIANGESSLVEVVQESQAMLLDIVALMTKQ
                     RKEIGDEIRSALQEQRFIGTCPKCSKDLRIVRSRKGSEFIGCSGYPECNVTYPKPGGA
                     LVQPTEQKCEACGLPIVKVIRRGSPVKLQCIDPDCQTNQGKESAGVCPECGKELRVLY
                     SRAGKRFIGCSGYPECKRTYPLPQFGTLEFLGQKCPECGAPTLKVLGRGGWQFCANMD
                     CPTGKKAKKEGEEPKKTAAKKAVKKTVKKTATKKAAAKKAEDEGTETGAPVKKTVKKT
                     AAKKVTGSATGAAVKKTVKKTAAKRPAAKKKVSSAE"
     gene            complement(21794..>22030)
                     /locus_tag="PKM11_06030"
     CDS             complement(21794..>22030)
                     /locus_tag="PKM11_06030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48098.1"
                     /translation="DEIIACSVTDHDARVRCRGRFETPRKEVDIIVNVLQYGLKKKDM
                     VRIVAECGKRSFVSNVSMSIEDLEIEEKELIQLS"
BASE COUNT         4646 a         6361 c         6551 g         4372 t
ORIGIN      
        1 agaacgcagt gaccttgctc gttgatcagc ctcggaattc cgtcctcgcc gacctcgtag
       61 aaactgccgt ccgcgtgacc cctgcgcacc agacggtcga tgtccgcctg gcacagctcc
      121 atgcgggtgt cctggcagca tttggtgcag tgggtgcagc gcatcggtca gggaacgccg
      181 agggacgata taatcgtgag gggaccttgg gttatttacc tgacgagctt gttactgttg
      241 agaggagaga gatatgggcg tcagatacgg tctgttcaat cacaccaaga aggagttcgt
      301 agttccagag aagataccgg tggacgccgc cgatccgacg acctatccgt tcgccaactt
      361 catctcctac ctgatgatgg agagctggag gtacgaccac gtggccatca tggacgactc
      421 caaggacttc gactgccaga ggatgttcgg ttcgcagtac aaggaccgct ccggggagct
      481 gtggaacgag ttcatcatga taatgggctg gcagttcaag gacctgagat cgatctgaac
      541 ttcagaggac cttcatcatg ttcaggctct tgacctcgta gccgagcgtc tcgtacaggt
      601 gcctggccgc gtcgttgtag gcgaaaacgt gcagcgccag ggaatcgatc ttcatgcgct
      661 tggccttcgt ttcgatggcc agcatcatgg ctcgcccata acctttgccc cgcttgtcct
      721 cgtctatgaa cacgtcgtag atgaacccct tgcggtcctc gcccggctcc accctgagcc
      781 atagttggcc gacgcgttca tcggtgccgg cgtccagagc cttgtagaag tgatggccct
      841 cggtgcgaag tccgtccggt agaagattag catggacggt ctcggaccgt tgcagcgcct
      901 ccccgggctt ccagtacccc actttgacgt tctcgtccgc gtaccgtttt acgccgaccg
      961 ccttcatggc ctcgaactcc ttcttgttca tggggaccag acgaacctcg accatcctat
     1021 tccacctcgg cctgacgaat aacacgtaaa aaatatttca agtcgttgga tgggaacgga
     1081 cgaaatagga aggaaagggt ttgacggagg gcgttcagcc ctggaagcag cggtataccc
     1141 aatacttctt tccgtccacg gtgatctctt cgggcttggc cctggggtct ccgacggagt
     1201 agtacggggg gaaggccggg ttggccttgg tcacgcgcag ggcgtccttc tcgttggcga
     1261 acttcttctt tacttcctcg gcgaccttgt ccggtacgcc aaaggtcagt tctacggtta
     1321 ccatctgtgt tcctccttgt tagcggctct cgccgctgga acgatttaac acttgatagg
     1381 attataaggc tttgttacat gccagtgtaa ccggttgtaa gcgcgcgata cacgtatgct
     1441 cggcatgtaa cggagttaac aaatagcgat gaatcggttc acgatggtta tgaaaataaa
     1501 agatgaggaa aggggtttag aaggtaataa cggcttgatc acgccttgcg gcagcggtag
     1561 acccagtact ccttgccatc gaccttgagc ttctcgggct tggcccgggg gtctccgacg
     1621 gagtagtacg gggggaaggc cgggttggcc ttggtcacgc gcagggcgtc ggtctcattg
     1681 gggaacttct tctttacctc ttcagcgacc ttgtccggaa cgccgaatgt cagttcaacg
     1741 gttaccatgt tttttcctcc aaagtagcgg aacgagccgc taccagtaaa gtagtgaatc
     1801 agttaatagg gtataaacgc ttgttacacc agcatgtaac gagttgtcaa atcgcgtatc
     1861 gaccttttta aaatattttc aatggccagt atcatgggcc ggccgaggcg gtctgcgcga
     1921 caagatcgat gttgatggaa cgggcggaga ggcggtagac gatctccttg ctctcctcct
     1981 tgtacgtctt gaccagaaag ttggacttgt aaaggacttc cagctcccgg tagacggtgg
     2041 ctctctcccg gcgttcggcg aacctctcgt tgtacaactt gtagacgtgc accgcggaag
     2101 cctccccgtc ggccagcagc ctcagtatct tcaggcgggt gtccgaggac agcgcctttg
     2161 ccacctcctc tatctccata tcaccctggc atgccctttc cgattattaa ggtttgattg
     2221 aatcacgggg aagcgttgaa tagtggctaa cgctctttcc aggaagaggt cgtgaattgg
     2281 gccgactgac gatggtttac gtgcgggcga taaagggagg gttccgctac cggttctcac
     2341 tggccaagct gacccgttgg cccctgctcg gccgcatgat ggaccggacg ttcttcgacg
     2401 gcgacgatat ctacgtgctg cccaaggagt cctcgctcaa ggtgcgggac atccctctgg
     2461 acctggccgc gccggaacgc gaggacaccg tgctcccctc ggaggtcatc aggcacttca
     2521 tcgagcggtc caggtaccat ttcgtcatgg attattgcat ttgccggacg tccgcccatt
     2581 gcgaagatta cccccgggaa cttggttgtc tcttcctggg caaggccgtg ctcaacattg
     2641 acccgcggtt gggacatctg gtgagcaagg aggaggcctt ggcgcacctg gaccgctgcg
     2701 agcgggccgg gctcgtccac ctcataggac ggaacaagat cgatagcctg tggacctcgg
     2761 gaaaaccgaa ggaggacctg atgaccatct gcaactgctg cccctgctgc tgcctgtgga
     2821 agatgcttcc gcagctggac ccggccatat cggtcaagat gaaaaggctg cccggggtgc
     2881 gtctatccgt tgatgagggc aagtgcacgg gatgcgggct atgcgtggaa ggctgttacg
     2941 tgaacgccat aacgctgagg gagggcaagg cctgcatcga ccaggagatg tgcaagggat
     3001 gcgcccgctg cgcccatgtc tgcccggaga aggcgataac cctgcacctg gaggacatgg
     3061 agttcctgga gcgcaccgtg tccattctca cccccttggt ggacgtgacc aaggaatgag
     3121 acaccgtccg gtttatattg cctcccggga atagctatat cgcaggccct tggaaggacg
     3181 aggaccgcag cactatcctg gtgatcggca tggccctcta acgcgaggat cccgcccgtg
     3241 tcgagtcgta atggagggag agagatggtc agaagcgtta cctacgaagt ggtgaagcat
     3301 ctcggagacg ccgagctcag gagatatgga gatctggtac tggccaccgt ctacgatatg
     3361 gacgacgatg aggcgttctc gctcctgttc cagtacatcg gcggaaacaa cgacaaggag
     3421 agcaagctgc cgatgaccgc cccggtggtc tcccggaccg gcgaacttgc cggtcacgac
     3481 tcggaggcga tgatggcctt cgtgctgccg tcggatgtca ctttcgaaga ggcaccgaag
     3541 ccggcggacc cccgggtggc catcgagctc aagaaggggg gcctcttcgc ggtcatgcgc
     3601 ttccgcggcc gcgccggagg cgtcgacgtt caaggtcgta ccgaggagct caggaccgaa
     3661 ctgaaggaag ccgactacgt catggacgga cgtccgttcc tcatgcgcta caattccccc
     3721 ttcactccgg gattcatgcg gcacaacgag atcgccgcac gggtggtccc gggaccggaa
     3781 aagagggaat gatcaggcct ttagccgggc ggagccggtc ttgatcatgg cggttatcgc
     3841 ggtgtataga agttccggct tctgcgagcc tatcagcacc gtgttcccgt tggcgtaggt
     3901 tatgcgcacc ccacggtttc ccgatacgtt gtaggcgcgg tggcctgagg ttcccttgat
     3961 cccccagccg ccgtactccg agatgggaga gtaccgtacc acggcatagg tcacgatctc
     4021 ctccttgaag atgcgcttgg gcttgttgat caacggaaag taaaatatgt tgacggtatc
     4081 ggtcaccgtg gtcctcatat taatggagag catgaacgct ggaaggagaa cgccgatcac
     4141 caccagcagg aaccacagga acccgtcggg acctggatta ttaccccacg gcacgtcgag
     4201 caatagttgc tgtatcgccc cccaccagac aaccccggtc ggaatcagcg tcaacaacag
     4261 ataccaccag gtacggaaat attgcacctc atggaaatgc tcgtactcgt cgggcatgaa
     4321 aggtcaaaat agctccgggg gataagaacc ttggccaggc agcaattgaa ataaagctag
     4381 gcgaccatat ctccggggat cacatggggc gaagggtgga gaggtccgac gaggaatgga
     4441 aacgggagct cgataccgag cagtaccggg tcctacgcag gaagggcacg gaggcgccgt
     4501 tcaccggcaa gcattacaag accagggaac ctggaacgta cgtctgcgcc ggctgcggaa
     4561 aggagctctt cgtctcggaa gataagttcg actcgggatg cggctggccc agcttcgtca
     4621 agcccctgga gggcgtggag gagcagcggg acctcagtca tggcatggac cgcaccgaag
     4681 tgctatgccc ggattgcggc gggcatctcg gccacgtgtt cgaggacggc ccgaagccga
     4741 ccggtctccg ctattgcatc aactccgctt cgttgaagtt caaaccgagg aagtgagaca
     4801 atggaaatgt ctggcaaccg tttcatgaag aagcaccact ccaagaagac gggcatgccg
     4861 cccggttcgg tcatctatgt gggtgatgga agcccatcgc ccacggaggt ctcggtgatc
     4921 gactacaccg aggcggacgt cctggagaag aagggaataa ccttcgatga gtgcatgatg
     4981 atgcgggaca accccagcat aacctggatc aacttctccg gactggccga cgtggagcag
     5041 atcaagaagg taggcgacat cttcggactg caccccctgg tcatggagga catcctgcac
     5101 atggggcagc ggcctaagtt ggagctgtac gacaaatacg tctacctggt ggtcaagatg
     5161 atctaccggg gtgacaacgg caaggaggtc acctacgagc agctatcgat cgtgatgggc
     5221 aagaactacg ttctcacgtt ccaggaaagg gagggcgacg tcttcaacag catccgggaa
     5281 cgggtaaagg gcaataaagg acgtttgcgg aagtcagggg cggactatct ggtgtactcg
     5341 ctcctcgacg cggtcgtaga caattacttc ccggccctgg agaagatagg cgacttggtg
     5401 gaggacatcg aggaacgtct ttcagacaat ccggagcagg acgtgctgag cgacatctat
     5461 cggctcaagc gcgaggtcct attcttgaga aagtcaatct ggccgataag ggaggtcgtg
     5521 gcggccatga tgcgccaaga catcgagatc gtgtcaccga acaccaacac ctacctgcgg
     5581 gacgtttacg accattccat acaagtgatg gatgtggtgg agacgtacac cgacatgctg
     5641 tcggagctaa cggacgtcta catgtccacg gtgagcaacc gcatgaacga gataatgaag
     5701 acgctgacca tcatcgccac catcttcatt cccttgacct tcatcgtcgg gctttacgga
     5761 atgaacttca agtacatgcc ggagctgacc aatgaactgg cgtacccggt ggtgctggtg
     5821 ggcatggcca tcgtatccgg gatcatgctg gtctacttcc gccgcaaggg ctggctaggg
     5881 taaaatggac gcccttacgt tggtagcctt ggcagggatc gcgctgtccc tgctcttcgc
     5941 cttcaccaac gggtataatg acgccggggc ggacgtggcc accatcgtat cgtcgggagc
     6001 cgcctccgtc aagggggccc tgctcatggc ggccaccaac aatttcatcg gtgccttgat
     6061 cggaggcagc gctgtcgtgc tcaccatgca gggcgtccta accaacgaaa tcgtcggctc
     6121 ggtcggactg gcgatgttct ccgcggtggc cgccgccaac ctgtggaacg tggtcacctg
     6181 gtactatggc atcccgtcgt catccactca tgccctgata ggcgggctca tcggcgtcgg
     6241 gatcgccttc cacggtcttt cgggcgtgaa ctggggctgg aacgaacttc tgaccggcca
     6301 gctgacgggc gtggccaagg tcctgacgtt cctgctggcc tcggttcttc tgggattcgg
     6361 cggatcgttc atcctgatga agctggccag gctgttcttg cgtggggcgt ccgtcgacgc
     6421 caaccgcccg atgaagagac tgcagtggtt gaccacggga gtgcagacgc tggcccatgg
     6481 agccaatgat gcgcagaagc agatggccct ggtagcgctg ctgttggtgg cgatgggatc
     6541 gtccactctg gaagtgccat tgtgggtgag ggtggcctgc gcggcggcca tggctctagg
     6601 tacgctcggc ggcggttacc gcatcatgcg caccgtggga cgaaagatat tcaagatccg
     6661 gccggtgcac gccctggtgg cccagaccaa ctcatccctg acggtgatat tcgccacctt
     6721 actgggcgct cccgtgtcgt ccacccaggt ggttacggcc ggagtgatgg gcgtcggttc
     6781 ggcggagaac catcggctgg tgcactggag ggtgggcaag gacctggtgg tgtcctggtt
     6841 catgaccata cccgcggcga cgttgttgtc cgtggtcatc gtgatcgtta tgagagcttt
     6901 gctggaggtc tgagatggaa gagaagaagg gtctgctgga cgggttgttc cctccgaagt
     6961 atgatttcaa cgccatgctg gtgggtcagg ccgaggacac cgccaaagga gtggagctgc
     7021 tgttatccgc tttgcagggc gagcgggacc atcacctgag cgcgctgata gagcttgacc
     7081 ggcgcactga tgagttccga catgacatgg agaggaagct gggggaggcg ttctccacgc
     7141 cgttcgaccg tcaggacatc tataccatgt ccagacagct cgagctggtc atgaacttcg
     7201 ctcggacgac gctactggag atggagacct tcggcgtgga gccggaccgc tgcatgctga
     7261 agatggccga gcatctcctg gtcgggacca gggaggtggt ggaaggggtg aaggccctag
     7321 ggaaagggct ggagaggacg gacgatctga tcaagaagat gcgggaggag gagcagagca
     7381 tcgaggaaac gtatgtggcg ggaatgcaga aggtctttct gctgcccgac cacatgatgg
     7441 tgctgaagaa gagggagata taccatcacc tgaaggacgc cggacgggcg ctgagcgcta
     7501 cggccgacat attgcaccgg gcggccttcg ggatgggcta gaggtctatc gttcccacga
     7561 tgcgcagctt gcccccttcc aggtaatgca tcactgcccg gtcgccggga ccgtagatca
     7621 acggcttctc caaggtaagt gtcacctgcg gcgtacgggc ctcgccgctc accgacgtga
     7681 cgcggcaggg caggaactgc atccaatggc ctagatgcat taccatgcct tccttgatag
     7741 gggattgcca gtacttgacc aggttcaatt tgacgttgag ctcggagatc accttcatct
     7801 ccggatcgtt cgttagaacg taaccgcggt ccaggtcctc cgcctctatt cccttgaggg
     7861 cgaacccgac gcgatcccct ttgtaagcga catcgaaatc atcgtcatgc ttctgtatgg
     7921 acctcacgag ggccgtgcgg tccgtaggca gcaccttcag gctgtcatga cgattaacga
     7981 cgcccttggc cacgtaaccg agcaccacgg ttcccactcc cttcacgttg aagtggtggt
     8041 ctatggggat aactcccttt ccctcgccgt gcggcttgat cttcgacgcc tcgtcgagca
     8101 ggtactcccg gagctgaatg agatcatctg gcatgtagat gtagttcatc aggaccgtgt
     8161 ccttgatgag cggggcgatg cggtccggcg tcagatagtt ccggaggatg aacaccccgc
     8221 gcttgacgtt ggcgcaatcg agcatgagca acgtctcgcc gaaggcggcg tttatctcgt
     8281 ccaccacgac cagggccatc tccgccaggt tgacgcagaa gtacaacgag ttgatgcggt
     8341 ccgggtactt ggccggctcc agtatgctga ccgtgtcctg ccccttcttc atgtcgtaga
     8401 tggtgatgtc gctgacggtc cctttctttc ccaggtcctt ggcgtatccc aaggcgccta
     8461 ccgccgccac gttcaggttg cccatgcacc tagtcaagcc atcggtgaag atatgccttt
     8521 cgccacgcca agcgttatct atttcgaatg gtcatctccg gaaggacatg ttcgagcacg
     8581 tggaccccgg caagcacctg gaccagaagg agtacgacaa ggtcgtcacc gaactgaagg
     8641 agcgcctggg tgagctgcag agacacgcac gcgacgctgg aatgcccatc atcgtggtct
     8701 tcgagggctg ggacaccgtg ggattgagcg aggtggtgaa caagttcatt ctccccctcg
     8761 atccccgagg gttcctggtg cacccgataa ccgcaccgcg ttacgacgag aagctgaggc
     8821 cgttcctgtg gcggttcatg gttcgaattc cggcccgggg acgtatagcg gtgttcgacc
     8881 gctcctggta cttccgttcc ttggccaggg ccgagcgcag ggaggaggcc gctcgcctgg
     8941 cctggcggga gatagccgag ttcgaggaga tgctctccga cgacggctac ctgatcatga
     9001 agttcttcct gcacatcggc aagaaggagc acaagaaacg tcttgacaat tacaaggaca
     9061 aggacctcga ccagtgcgcc ataagcacct cggaggtgga cttcttccgc aagtacgaga
     9121 agatggtccc gctcatcgag gagatgatcg agagcaccga ccgggagtac gccccgtgga
     9181 ccatcgtgga ggcggaggac cagaagttcg cctcggccaa gatactcacc accgcggtgc
     9241 gcatgttgga gtacggactg tcgaagatgg agagcaagaa ccagatacac atggacagca
     9301 accccctcat caagggcggg cagatgttca actcctcccg aggttccgtc gatctcagca
     9361 agaaactgtc ccaggaggag tacaaggtca agctggagaa gctgcaaaac cgcattaagg
     9421 tgctgcagtg cgaactgaac cggctcaaga taccgaccat cgtggtgttc gagggctggg
     9481 acgccgccgg gaagggcggg gcgatacagc gcctgacggc cgaactgaac ccccggggct
     9541 acgaggtcgt tccagtcggc gttccgacgg ccgatgagaa ggagcatcac tatctctgga
     9601 ggttctacca gaagctgcct ccggccgggc acgtgcgaat attcgatcgc tcctggtacg
     9661 gacgggtgct cgtggaacgc gtggaggggt tctgctccac cgaggagtgg aagcgcgcct
     9721 acaaggagat caatctcttc gaggagatgc tggtggataa cgggggcgtc ctggtgaaga
     9781 tctggctgga gatcgacaag gacgaacagt tgaagcgctt cgaggaacgc gacaaggacc
     9841 ccatgaagca gtggaagatc accgaggacg attggagaaa tcgggaaaag tgggacttct
     9901 acgggcgggc ggtggacgag atgctgttcc gcaccagcac caagctggca ccatggacca
     9961 tcgtggagag caacgacaag ttttattccc gagtgaaaac gttgcagacc atcgtgcagg
    10021 ccatggaatc caagctcccg aaaaaggact ccaaatgatt aatatcccta gggatatgcc
    10081 catgcaatcg aagtgatcaa gatgtctagt ttccaagagt tcggtctcag ggatgagatc
    10141 atgaaggcca tcgagcgcat ggggttcgta gagccgaccc cggttcaggt ggcgaccata
    10201 cctcttacca tgaagggtaa ggacgtcata gcccaggccc agaccgggac cgggaagacg
    10261 gccgccttcg ggatccccat cctggaatcc ctaaccaagg gcgtcaagcc tttctcgctc
    10321 attctcgttc cgaccaggga gctgggttcg caggtatctg atgaactgaa gaagctggcc
    10381 ttcttcatgg acgacgtgcg cgtgcttccc gtttacggcg gcaagtccat cgacgagcag
    10441 gtggacgcct tccgcaaggg cgtggacatc gtcgtcggta ctccgggacg ggtcattgac
    10501 cacctgcacc gggggacgct agccctcaat gagatcgaag tgctggtgct ggacgaggcg
    10561 gaccgcatgc tggacatggg gttcatcgag gacatcgagt acatcgtctc caaggtgaag
    10621 aagcagcggc agaccatgct gttctcggcg accattccgg agaccatcaa ggagatcgcc
    10681 gccaagcaca tggtcgatcc ggagaccatc atgatcggcg aggagcagat agtgctcccg
    10741 acgaccaaac aggtctactt caacatcgag cgcaagaaca agatctgggc gttgtgccgg
    10801 gtactggacg cctacaagcc gaaggccata gtcttcgtgc agaccaaggt catggtggac
    10861 atccttgcca aacgcttaga ttcctacggc taccgggtag gggaattgca cggagacctg
    10921 acccaggccc gtcgggagaa ggtcctgaag gagttccggg agggaaagac cgcggtgctc
    10981 atcgccaccg acgtcgccgc tcgcggactg gacatcgagg gcgtaacgca cgtcatcaac
    11041 tacgacattc cggaggaccc ggaagtttac gttcaccgca tcggccgtac cggccgcgcc
    11101 ggaaaggaag gcatagccat caccttcatc acctccaagg aagtacacct tctgaagaag
    11161 atcaatgagt tcggggtaac cgagatagcc aaggaagagg tcccagagag cggccgcaag
    11221 gatgtcatcc gcaaggtcat ggacttcgag gaccaggccg acctgttcgg catggtgctc
    11281 ttcaaagtgg tcgccgggga gaacgaaccg gtggagcgcg ctgacctgtt ggcgctgctc
    11341 aaccgcaaga tgaggatccc cgagctagcg ataggaaaca taaacgtcct taaggaccgc
    11401 acggagttcg aggtccacaa ggactccgcc aagatcgtgc tgatggagct caagacgctg
    11461 agggtcgggg acaagaagct gaaggtggag atcgttcacc gcgagcttcc tccggtttcc
    11521 atgcagtgag cttcaaacgc ctttcatttt attgataaaa aaggaatagg taaggggttt
    11581 cacttcttgc gcttccttga gatggtctga agcagggcca ccagcgggat cttgctcttc
    11641 ttgtccgagt tggacacctt gccggtgagc agaatatcct tcttgaacaa ggtcaccgcg
    11701 acgaacatcg ccagcagcgc cacggcagcg gtgtaggcta taccaccgag caccagcgag
    11761 tagtcatcga acatcaggga gcgcatggcg atcatggggt gcgagaacgg tatggccaga
    11821 accagtacct tggccaccat cggcagcgtg tcgacgtcag tgaacatggt cacgaacatg
    11881 gggatcatgg ccaggaacgt cacgggcatg gtcatggtct gggccgcctt gtagttcttg
    11941 gtgaatatgc ccagtatcat gcacagcgcc aaggcgaaca ccaacgaagc gaacagcgac
    12001 atcccgacca ggatgtaatc cacgatgctc agggtcagcc cgaactccgc caggtcgatg
    12061 gagctggaac ccatcagcga atcgaagtag tagctcatgc cgaacatgta gatgaccgcc
    12121 atcagcagtc cgaccagcgc cgcgccgatc agctttccga acacaatgga tgttcggctc
    12181 acgggcatcg tgagcaatgt ctccagcgtc ttgttctcct tctccgatcc catggacgat
    12241 ataacgatgc ttcccgcgta gattatcacc atcatgacga tcagcggcat gacgaaggat
    12301 tgcgacgaca tgacactgga gatggttatg ggagatatcc cggtcatctc cttgcccttg
    12361 aacagggtgg tctcgtaata ctgcgtggga tccaggatga gggaggcgtt gtcgctcatg
    12421 ttatggttga tgagcgtcgc cgagatggcc tggtcgacgt acatcaggtt ggcatcggcc
    12481 gccgcccctg gtacggaatc cattatcccg gcgcccttca tgatccagaa gatctcgatg
    12541 gtgccttggg tatcgttctc gatgttcgag gtgaagttgg ccggtatgac gaacagcgat
    12601 accccgccct tttcatccag gacgttcaag gcctcctgca cgtccgttcc gttgtacact
    12661 atatccgagg tggcattgaa gacggccatg gccactaacg agagggaacc gccgtcctga
    12721 ttgatgaccg cgatcatcgg cggttcctcc agctgctcct ccacgccccc gaacaccccg
    12781 ccgagggatc cgaagaggac ggcgattatg attatcggaa tgagggtggc cggggtcagc
    12841 agctccttga cctccttcct aattatcttg gagagactgc tcatttcctc accaccttaa
    12901 cgaacacttc ctcgatgttc tgcgcatcgt acctctgctt aagctcggca ggcgtacctt
    12961 ccgccacgat catcccgtcg ttgatgaggg cgatgcggtc gcagagaagt tcgacctcca
    13021 gcatgttgtg cgacgacaat agcatcgtcg tcccttgcgc cgcgaagctc ttgaccgtct
    13081 tgcgtatctc ctgggcgttc agcacgtcca ggccggacgt cagctcgtcc aggatggcca
    13141 attttggctt tatcatcaaa gcccgggcca ccagcaaccg ccgggccatc cccttgctgt
    13201 aggtatcgac cttgtcgtca atcctctccc cgaggttagc tatctccatc cccctggcca
    13261 ccagcgcctc ggcctcatct ccttcggcga agaactgggc gatgaacttc aggtactccc
    13321 gtcctcggag gtgcttgtag gccccggcgt cctccggcag atagctgatc acccggcgga
    13381 cctcttccgg cttggccctc agatctatcc cctgtatctg tatggtccca ctggttactt
    13441 ccagcagcgt cgcgagtatg cgcaaggtgg tggtcttgcc cgccccgttg gggccgatga
    13501 gaccgtagac ctcgccctcc tttacatgga aggagatgcc cttgaccgcc tggaaggttc
    13561 cgtatctctt gaccagatcc ttaacctcga cagcgtacat ggtatgcttc cccgttccag
    13621 gaagtgaata catctaaaaa aataatgcca tgaatctact gagaaacgag acggggtgaa
    13681 ggatagataa accctaacgt gaattggacc acatggaccg ggataggttg gccttgcttg
    13741 gcgcatccgc cgggattatc ggcgtggtgg ccttccaggc gctgttcagc atctccctgc
    13801 tgtaccatcc cgattggagg ttcggtctgg acctgatgag cgagctggga acgaccgaac
    13861 cgtatacctg gctcttcaac atctcagtaa tggtaatggg ggccttagga gtagctttct
    13921 cattatcgct cctaaggttc ctttattgga gcttgctggg gaagctctcc gtggtcatgc
    13981 tggtggtggg ctgcacctgc ctgttccttc tgggcgtatt taccatgaag caacgggctt
    14041 tgcacgacgc cctggcctgg aacttcttcg tattgatcgt gattggactg ttggtccttt
    14101 ccatcccgat gtacttgtac tggaataagg ccagatgggc cttcgccgcc accctggcca
    14161 cggtggtcct aagcctaaca tgcctgatca tgatcggcct gggacttatg aagcaccacc
    14221 tagccgaggt tctggtagtc tacgcgctgg gagcatggat gctggccatc tccatcttca
    14281 tggtcctgcg cctgcggagg aacgaccttc ccttcactcc ctataacgat agctgatgtt
    14341 gcagctcccc tcgcggctga ccatgcatgg ccccatcggt ctcttcgggg agcatccctt
    14401 gccgaaggcc gggcattcct cggaacggat gatgcctcgg agcacctcgc cgcagcggca
    14461 gccgcccatg tcctccttga ccttcggagc gtcttttaaa acgtcctcat acaccaggcg
    14521 ggcgttgtgg tccgcgaggt cgtccgagac ctccaacgag ctcaggggga gcaccgggaa
    14581 tcccctccat gcacggtcct cggccttgaa ggccttggcc agcatctcac gggccttcag
    14641 gttcccttcc ggccggacga cgcggggata ttcgttctcc acctcgctgc gtccttcctt
    14701 cacctgcttg gccagcatgt agaccgccat gagcaggtcc agcggttcga aaccggtgac
    14761 cacctgcgga acgcctttag gaccggcgaa ctcgttgaat atgtctatgc cagtgatggt
    14821 ggccacgtgc ccaggctgta taagtccgtc aatgcgcacc tcgcccatgg cgaacaacgc
    14881 ctttagcgcc ggcggtagca aacggtggca gctcaaaacg ctgaagttct tgggaggatc
    14941 gtgaagaagc gcgtaggccg tggacgggct ggtggtctcg aaccctatgg ccatgaagac
    15001 catgcgttcg acgtcagcgc tcatgcggag cgcgtcctcc acggaataca ccacccgaac
    15061 atcggctccc tcggccttta cctccgccaa agaaccgatg ggcgtgggaa cggccatcat
    15121 gtccccgaag acggttatgg agacgcccgc tctggctaac gtgatcgctt ccacgacctc
    15181 cttggtggtg gtgacgcaca ccgggcatcc ggggccctgg ccgatggtta tgccgacctc
    15241 ggtcagcatc ttctccaggc cgaacttcac cagggtgtcc tggtgggtgc cgcagacgtg
    15301 catgaagcgc agttccaggt ccatctcctt gagcttggac atgatctttt tggccgtcgc
    15361 ttcgtcccgg aaccgtaggt cgttcattcc tgcaccacct tcatggacgt cacccgacac
    15421 gattgaccct tgaggacctt tacctttccc ttgcacctgg gacaggccag ggacggcatg
    15481 gacatgtgaa actcctcgcc gaccttgtcg gccttgccca cgtatccgca ggaaaggcat
    15541 tgcagctcgg tctcctccgg ctgtatcacc agagtggagc cttccaaggg cgtatcacga
    15601 gtgatgatct cgtaggcgaa ctgaagctgt tcctccccca agaaggtcag ctcccccaag
    15661 ctgagcagca cctcctccac ccggaggacc tcgtgcttct ccagctcctt gaggacgctc
    15721 tccacgatgc cggccatgac ggaaacttcg tgcatcgttt aggccaatcc atcatccgat
    15781 attaatggaa tgcctcccgt ccggcggaga tggcgaagga aggctggcca taaggaacct
    15841 agatatatcc ctaggcaaat acgaagaccg ttcaccatgc cagaggaaga atcgcgcaac
    15901 gaggctttcg agtccatcat cgagggcaag aagatggagg cctacgcgga gcaccgcacc
    15961 aaggagatgc acgcttgcgc gttgtgcggg gccatcggct acaagaagcg cccgatgagg
    16021 ccggtgggac acaagtggat ctgcatcgat tgcctgcgtt ccttgaagga gaccttggac
    16081 ggacttgacc agtgggaggc cgagatccag ctggagaagg agatgtccaa gaagatcgac
    16141 gagaccatgc gtacctgatc catcacttgt cgggataggc gcattcgttc ttgatcgggc
    16201 attgggcaca tttgggattt cggggaaggc atatcttctg cccgaagcgg accatggtgc
    16261 cgttgatctc gcaccacaac gtccgtggga acacctttcg caaggccatc tccgtctcgt
    16321 cgggggtggg gcaatcgact atgccgagac gattgctgat gcggtgtaca tgagtgtcca
    16381 cgcatatcgc cggttccttg aaggcatagg tcatgacgca gttggcggtc ttacgtccga
    16441 ccatcggcca tttggtcatc tcgtcgatgt cccgaggaac tccgccgttc tccaccacca
    16501 gccgggcgat ctcctttatc gccttggcct tcgcccggta gaaaccgacc ggacggacca
    16561 acgcctcgag ctcaccgatg tccgccgcgg ccatctcctg cggggtgttg aaacggccga
    16621 acagatttga cgaggcgtgg aaggtgttca ggtccctggt gcgctgcgac agcaccgtcg
    16681 ccaccaggat gtggaagggg tccttttccc accaggtgtc ctcctcatcg atcaacccgg
    16741 gaaaggccat cccgttgatc gaagagcgca tgctggtcaa cagccaccta aggtccatga
    16801 gcagcctcca gatgttgcat cgcttccccg atggtgtaca gagaaccgct gacgaacagg
    16861 aaaccgtcct ttccggtcat cccttccgcg aggtccatgg cctttccgac cccatgaacc
    16921 gcctggcatc tggggttgaa aggcagtacg gcctccagca tctcttgcgg agagaacgcg
    16981 cgcggagatg atgaactggt gcatatgacg cgatcgaaca acggggccag atgggccatc
    17041 gcgccccggg cgtccttgtc cttcagcatc ccgaccacca tgaccctcgg gcgtcccggg
    17101 aacatttcca gttcggacgc taccgccctg gccccgtccg gggtgtgcgt cacgtccaga
    17161 acggtcagcg gagaacgacg gaccacgtcc aaccttcctg gccacctggc cttggatagc
    17221 ccttcgacga tgctgtcccc ggaaatatcg atattcttcc cgacctccag ggccatctcg
    17281 gcggccaccg cggcattctg gcattggtaa tgtccgagca tgcccagctt cacctccctc
    17341 cccagtgaat ccagcctgac cgtcacccct tccaggtcct ggccgacgca ctcggcctga
    17401 aagtcccttc ccaatgatct gataatggaa cccttgcaat cggccatcca agagaccacc
    17461 cgcatcgcct ccggggtctg aggggagcat atcaccggca caccgtcctt gatgatggag
    17521 gccttttcgt aagcgatctt gccgatcgta tcgcccaggt acgtcgtgtg ctccacgctg
    17581 atgggagtga tgacgcagca gcgcggatgg atgacgttcg tggcgtccag acgcccgccc
    17641 atgcccacct cgaccatcgc ctcctccacc ccgctgtcgc tgaaatgaag gaacgccaac
    17701 gcggttgtta tctcgaagaa ggtcagaggt ctcgggaaaa cgccggacgt cgcaagttcg
    17761 cgcatctcag agacgtactt ggctaatcgc ccttcggaca tctccttgcc gtccacggtc
    17821 atcctctccg tgaagcggac caggtgcggg gaggtgtaga gaccggtgcg gaagccggcg
    17881 ctgcgaagaa cggacgcgcc catggccgat accgaccctt tgccgttgga gccggcgaca
    17941 tgaacgatgc cgaagcggtt ctgcggatca ccaagcctgt tgaggaggag gcgcgtgttg
    18001 gacagtccca gcttgatgcc ggtgctctcc agggagtata gccattccag atctttaagc
    18061 ggtgcggagc tcatcccttc aactccctca cccaggttcc caggtccgaa ccattttcgg
    18121 tggccaggcg cttcatggcc ttcatgaccc cgctgccata ctgggcggcc ttcttgggcg
    18181 ctttggccga gtttaacccc ataccaaggg cgatacgacg cagaggtagc ttgttgccca
    18241 gttcccctac cagtctctcg gccggaatgg acagggccgt ctcgatgacc ttcggaccaa
    18301 gatagggaca gaacagcttc ttgccgaaac cctgggttat gcgcgcctcc ctgggacatc
    18361 cctcggagag cagacgctga acgtcccctt tccgcgcttc atccagttcc ctgggcgaca
    18421 gtgaagaata gcgggcgtaa cctccgaaca gctcgtccgc cccttgcccg ctgagcagaa
    18481 cctcctcggc caccctgctg cagacgacgt acagaggcac ctcgaaggag atggtgaccg
    18541 ggtccattac gcccacctca tccctcaggt gagcgaccgc gttccgcagc atatcatcat
    18601 ttatgacgat aggttcccag ggaagcccga tctcttcggc gccctttctt ccggccccga
    18661 tgtcatggga gccgggatac cccaccgtgt agagccggag ctcggagaac ggccgggcca
    18721 aaacggtgag caatgtgctg tccagaccac cggagaagag aaccgccgtc ctgcccttag
    18781 atatctctct taggcggtcg gtcaatgctt ccagaagcct ctcttcgctc aggtcaagat
    18841 tcagtgtgtc ccgctccctg atggtccatt caccgatggc tgaatagcat taataatcat
    18901 taggataata ccaagcggag catatggaca acgtcaccag gataggcgtc tctctggaac
    18961 ccgacctttt agaggacttc gacaagctca tcgatcggaa ggggtacata acccgttccg
    19021 aggcaatacg ggaccttatc cgcagcgccc tggccaagga gatcctcaag gaggacgaga
    19081 acgccgtggt cttcggcacc atcaccctgt tctacagtca ccacaaggga ggcgtcaagg
    19141 aacgcctgat ggacatccag cacgagttcc accagcatat cctttcgtcg gtacacgtcc
    19201 acctggacat cgagcagtgc ctggaagtgc tcatcgtgaa cgggaccgta aaggaagtca
    19261 gacaattgtc tgacgaattg ggaagcgtga agggcgtcac gcaccgcacc ctgcatcgca
    19321 ccccagtgag cctgggggag gaagcgatgc gcacgcacat tcacgagcaa tgatgggagc
    19381 tgacgttcgc tacgggggca gataaccttt tttaaatgtt aacccttgat gcccactgat
    19441 gaagagactg gtcatctccg agaagtccaa cgccgcggcg cgtgtggcca ccatcctttc
    19501 tgacggtagt gccaagcgca agagcgtccg cggagtgcag gtgttcaatt tcgagagggg
    19561 cgaggacgag ttcttcgtgg tgggcctgcg cggtcacatc atcgagctgg actatccccc
    19621 ggagttcaat gactggtcga aggtggaccc catggacctg gcgaaggccc agccggccaa
    19681 gagggtcacc gccctcaaca tcctcaacac cttgagcgag ctgtccgcgg aatgcgacga
    19741 ggtgatcatc gccaccgact ttgaccgcga aggagagctg ataggactgg agaccgtctc
    19801 ccttctggac aagcctcccc gctccgtcaa gagggtgcgc ttcagcgctc ttactaagta
    19861 cgagatagag ggagcgttca aggagcttac cgaacccgat caccggttgg ccgagtccgc
    19921 agagaccagg caggtcgtcg atctggcctg gggcgcggtg ctcacccgat tcatttcatt
    19981 ggccagtggc cagatgggca ataacttcct ttccgtggga agggtgcaga gccctaccct
    20041 gaccctcata gtcgaccggc acaaggagat caccgagttc gttcccgaac cgtactggac
    20101 cgtggtggcc cgtttggaga aggaccagga gttctccggg gaccatatcg ccaacccgtt
    20161 caaggacgag gcgaaggccg acgccgtgcg ccagagggcg gactgcggca aaggaaaggt
    20221 catgggaatg gagcgcaagg agaaggacga gtatcccccc gccccgttca acaccaccac
    20281 catgctcagc gaggccaaca agctaggact gtcgccatcg ctggccatga agatagccga
    20341 ggacctgtac accgccggtt acatttcata tcctagaacg gacaacaccg tctacccgcg
    20401 ctccctgggc ctgaagaaca tcctggagaa gctgaagaag tccgacctgg gcaaggaggc
    20461 cgcggagata ttggcgcagg agcagatccg gccctcccgc ggccgtgtcg agacgaccga
    20521 ccacccgcct atctatccga ccgaggcggc caccaagaag gagctcaagg gcagcaagtg
    20581 gacgctttac gaactggtga ccaggcgctt cctggccacc ctggccccat ccgctcgttc
    20641 cgaatccgcc agatgcgacc tggagctggg cggggaaccg ttccgcgcgg aaggctatcg
    20701 catgctatcg ccaggctggc gcaagtacta cccctattgg agggtcaccg aggtgctcct
    20761 gcccgagctc annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    20821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn naccgaaagc
    20881 cgtatgacgg cccagctgga aaaggacatg gactccatcg ccaacgggga atcgtccctg
    20941 gtagaggtgg tccaggaatc ccaggccatg ctcctggaca tcgtggcgct gatgaccaag
    21001 cagcgcaagg agatcggcga cgagataagg agcgccctgc aggagcagcg cttcatcggc
    21061 acctgtccca agtgcagcaa ggacctgcgg atcgtccgct cccggaaagg aagcgagttc
    21121 atcggctgct ccgggtatcc ggaatgtaac gttacctatc ccaagcccgg gggcgccttg
    21181 gtgcagccta ccgagcagaa gtgcgaggcc tgcggccttc ccatcgtcaa ggtcatccgt
    21241 cgcggatcgc cggtcaagct gcagtgcatc gatcccgatt gccagaccaa ccagggaaag
    21301 gaatcggcgg gcgtctgccc ggaatgcgga aaagagcttc gcgtcctcta ctcccgcgcg
    21361 ggaaagcgct tcatcggctg ctccgggtat ccggagtgca agcgcaccta tccgctgcct
    21421 cagttcggca ccctggagtt cctgggccag aagtgcccgg agtgcggagc tcccacgctg
    21481 aaggtgctgg gaaggggcgg ctggcagttc tgcgccaaca tggactgccc gaccggcaag
    21541 aaggccaaga aggagggcga ggagcccaag aagaccgccg ccaagaaagc ggtcaagaag
    21601 accgtgaaga agacggctac caagaaggcc gcggcgaaga aggccgagga tgagggcacg
    21661 gaaactggcg cgccggtcaa gaagacggtg aagaagacgg ccgccaaaaa ggtcaccggt
    21721 tcggcgactg gggcagcggt caagaagacg gtgaagaaga ccgccgccaa gagacccgcg
    21781 gccaagaaga aggtcagctc agctgaatga gctccttctc ctcgatctcc aggtcctcaa
    21841 tggacataga tacgttagag acgaagctgc gctttccgca ttcggcgact atgcgcacca
    21901 tgtccttctt cttcagaccg tactgaagaa cgttgacgat gatgtccact tcctttcgcg
    21961 gcgtttcgaa acgcccgcgg cagcgcaccc tggcgtcgtg atcggtcacg ctgcaggcga
    22021 tgatctcgtc
//
LOCUS       DAOPZI010000026        20895 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_2609_length_20895_cov_10.283013, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000026 DAOPZI010000000
VERSION     DAOPZI010000026.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 20895)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 20895)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20895
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2609_length_20895_cov_10.283013"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..547)
                     /locus_tag="PKM11_06035"
     CDS             complement(<1..547)
                     /locus_tag="PKM11_06035"
                     /inference="COORDINATES: protein motif:HMM:NF015558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HNX48099.1"
                     /translation="MSYVDDAKLYLRVGRKEVPGLLFCLIVAVASYLVTRGTLFEGGP
                     RLLDSNLFADNPLASFLFKVGPIVLALLIGLLVNVSPIYPGGAYAGRFLLRLAIVLMG
                     ARVTLDVLSKASPVGIVIILAVMAFTVWFSLFLGRKVRLEKDASALIGTGNSVCGVSA
                     CLSVAPVIDAKAHNTHAVIGVI"
     gene            complement(597..2027)
                     /locus_tag="PKM11_06040"
     CDS             complement(597..2027)
                     /locus_tag="PKM11_06040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48100.1"
                     /translation="MNRSFLRAGRSLAALLLVVSMLAPLLFMSAPVSAGDGVMNLTIG
                     GSGSAPWTIANIVPGDNGTELVELRNAGRIDGYVTIWFSDVVETDGGTDGRHLAEHFL
                     LAPSSVNMSSNISFPAPFTDMPRTSLDRSICIGPLKAGETINLTWAWEFFDSGAPQNE
                     AQGDGLSFTINYLMTATGPEDGVSWLVIDVLGTLTVVALNATGYVQEAFQATNANGTV
                     VLEFAAGTQILTENGTVPEWLVVTEAEQEDVLNGTNATALSPTYVISAFDQNNVSTNV
                     SFSSGASLIIGFDPEALPEGFVPGLYQLVDGVWVRLNETGPFYSWYAYADIIGTGSYA
                     AGAYDDRDEYALLEISELTFKGTKKVFWWNVLPLFIKYNYKASVSLNVSNVGNAPGNF
                     TINIVLDDRVVDTVDVYLEAGESEQLTFQFNGVHKGQHHVTVGSLEEQFKTYTWINWP
                     LIWAIIAITLLIILVAYGIRRRQESN"
     gene            complement(2029..3480)
                     /locus_tag="PKM11_06045"
     CDS             complement(2029..3480)
                     /locus_tag="PKM11_06045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48101.1"
                     /translation="MISKKRLLTIVSLLIVVAFLNTGLFAAFSDVENSANNKISAYTP
                     KMWKSTTEDDFYNNTTKFEVHTLESPGDVTLAEKETAMSSLYLLAGGNTRDFYRYYTE
                     SNNWSQRANVPANVGYGGSMAFDESRYIYAMMGGGTRHFWRFDTQYNNWSKRADTPGP
                     VGAGGFLRNYNDGMFYALQGGNTGTLWKYNPSNDTWWTLTTTLPKIGETNAYGASMVV
                     YLGFIYIVRSTASPTNTNVFYQVSLDGITVTPITITNPANKGFGLGVSITHGQGAYLL
                     IGRGGDNREVYQYSITTKAFTKLGLVPKNSKLNVGSDLAYDNIRPFVTAGGNTNILLK
                     YNSTLRTWATMTSMPSPVKANFGSNLLYVAFATGYAPSGYLVSSVHDTGKANMKLDSL
                     FADYTVPSGTSISFKVRASNTRTWIPTPDDPNNQTGVNGSWDLTGVAWTTVTGSSIST
                     ITGQYVQWRVDMTTTVTTSTPILYEVRLYYRGF"
     gene            complement(3477..3965)
                     /locus_tag="PKM11_06050"
     CDS             complement(3477..3965)
                     /locus_tag="PKM11_06050"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: protein motif:HMM:TIGR02228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HNX48102.1"
                     /translation="MKWSSVGTAISVAVLALVLFMAVSPVIGFRFDPVRSGSMSPAIE
                     VGDLAISSSVDNEDIKVGDIIVFRHSGILICHRVIAINAEAGWIQTQGDANEDPDPYT
                     ITYDDVVTEVGLVVPYAGHAVLFLKSVYGWVLIFVLIAAMLLLGLYEDREKDDSTSGG
                     EQ"
     gene            complement(4023..4640)
                     /locus_tag="PKM11_06055"
     CDS             complement(4023..4640)
                     /locus_tag="PKM11_06055"
                     /inference="COORDINATES: protein motif:HMM:TIGR04088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SipW-dependent-type signal peptide-containing
                     protein"
                     /protein_id="HNX48103.1"
                     /translation="MQKKRIMISALALVVVALVASWGVNAYFNDVENNAGNKVTAATL
                     DLQVTSPASNVTAYLTQSGVYPGFTSAIPTSITLKNNGSMAGLLTVTIVQIVDTNGTD
                     TEPELVTTGNANGVAGVATGTGGDLSEVLSITITAGTFTYTGLLNGAMTNLANIPMAA
                     GSTLTFTVSFSVPTSADNQIQGDIVTFGLRFVLNQDADGNAGTQV"
     gene            complement(4942..5017)
                     /locus_tag="PKM11_06060"
     tRNA            complement(4942..5017)
                     /locus_tag="PKM11_06060"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4981..4983),aa:Pro,seq:ggg)
     gene            complement(5043..5234)
                     /locus_tag="PKM11_06065"
     CDS             complement(5043..5234)
                     /locus_tag="PKM11_06065"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit N"
                     /protein_id="HNX48104.1"
                     /translation="MIIPVRCFTCGKVVGSSYQTFVKRVQMGENPQEVLDDLDIKRYC
                     CRRMIISHSDLLGELIPLG"
     gene            complement(5241..5642)
                     /locus_tag="PKM11_06070"
     CDS             complement(5241..5642)
                     /locus_tag="PKM11_06070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HNX48105.1"
                     /translation="MSEVVNTSGKRKTAVARAVAREGTGKVRINSVPLDIVTPELARL
                     KMAEPLTLVPEKAAKIDIDVSVSGGGVMGQAEATRTAIAKAIVEFFHDEELKLAFKHF
                     DRSLLISDVRRKLPKKPLGRGARKKRQKSYR"
     gene            complement(5644..6063)
                     /locus_tag="PKM11_06075"
     CDS             complement(5644..6063)
                     /locus_tag="PKM11_06075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HNX48106.1"
                     /translation="MVAIIDAENHIAGRLATVIAKRIMKGEEIVVVNAEKIIITGERD
                     AVLAAYKQKKDLGNVKSGPFFPRRADLIMKRTVRGMIPWKTTSGRMAYRRLKVFVGVP
                     KEFVDSPKEKVDVAIKAGLTQYVTLSQIAEFLGSRVM"
     gene            complement(6068..6463)
                     /locus_tag="PKM11_06080"
     CDS             complement(6068..6463)
                     /locus_tag="PKM11_06080"
                     /inference="COORDINATES: protein motif:HMM:NF028445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18e"
                     /protein_id="HNX48107.1"
                     /translation="MRGAYQCRESQNMAHAKTDPNLLTLISALKAESRSSGAGIWRDI
                     ALRLEKAKANWAEVNLSKIERYASEGDVIVVAGKVLGSGAINKKVTVAAYGFSESAKM
                     KIEAAGGKNLTIMELVKEMPQGTGVKIMR"
     assembly_gap    6789..6888
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <6889..7614
                     /locus_tag="PKM11_06085"
     CDS             <6889..7614
                     /locus_tag="PKM11_06085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HNX48108.1"
                     /translation="GVMGAELDVALSMHTPYYIDLAGEGDLTRKSMDSIRWAGMMTQA
                     MGGNMVVTHMGLYGNISHREAAENISDRLEEIVTWWEKNKLTPRLGLETSGRKEVFGG
                     LDEIVELCDKFDVLTPVVNFAHYHARNNGMLREPEDFAEAFDQVKSYVGDLHYTHFSG
                     VEHEGGNERRVTPIKKGDLRFEPMAEFLADANLNATIISSSPLLEHDAMYMKVIYERV
                     MTKRVTKDIKVKKGKGAKDEDDE"
     gene            7611..8150
                     /locus_tag="PKM11_06090"
     CDS             7611..8150
                     /locus_tag="PKM11_06090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HNX48109.1"
                     /translation="MKETTAYILEEVRRTIEKVDEPLIDDIVTTLAAAPKIFIYGVGR
                     SGLVGEAFAARLVQIGLNVHFVGDTTTPIVEKGHVVLIISNTGETMSAVQTANIVRRL
                     GAVVISVTGSAHSKLGIASNMVMELVQPRDERKKKNAPLGTIFELSSMVMLDSMVPLL
                     MSKLDQDEASLRRRHAIWV"
     gene            complement(8151..8783)
                     /locus_tag="PKM11_06095"
     CDS             complement(8151..8783)
                     /locus_tag="PKM11_06095"
                     /inference="COORDINATES: protein motif:HMM:NF025819.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HNX48110.1"
                     /translation="MKRAPVIISGKDLEVEEMIPPVKERTLPHKWLPKEAASLYSDSK
                     AAEMYLFKTAEEKVRNHALSQVKAGLEVMGFLLGEVFTHQGIEYTVVRDVATTDLEAT
                     SVSVRFDPDGFESLFASLESARFRYVLVGWYHSHPGHGCFLSSTDVATQRGMFDRPYH
                     TALVVDPIRKEMDAFCLSNGDVRRKKFVVYWDEFQNPYYGESVRPKKIRT"
     gene            complement(8780..9286)
                     /locus_tag="PKM11_06100"
     CDS             complement(8780..9286)
                     /locus_tag="PKM11_06100"
                     /inference="COORDINATES: protein motif:HMM:NF012406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquitin-conjugating enzyme E2"
                     /protein_id="HNX48111.1"
                     /translation="MTLPLEILYIRLRNELEACHHYLPQEFDLSEERLTKLPLRVEVG
                     MEGIPGPVMENGKLVYRYSHRLDLIIGREYPFEKPLVIWKTPIYHPNIMMPEDGGHVC
                     IKLLSEWSFNSTLFNFIKGLESLLLSPNGNSPFGTDTCTAAAQYFNSTPRRTPPVIVA
                     PAPKVVGQ"
     gene            complement(9283..9528)
                     /locus_tag="PKM11_06105"
     CDS             complement(9283..9528)
                     /locus_tag="PKM11_06105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48112.1"
                     /translation="MVVRIRVRNAETGATVDMELELENTVEEIIEGVSAFWEKDPGAY
                     VIRKGRRLLRGQQKVQELDIQANEELELIPDPEGGNR"
     gene            complement(9588..10379)
                     /locus_tag="PKM11_06110"
     CDS             complement(9588..10379)
                     /locus_tag="PKM11_06110"
                     /inference="COORDINATES: protein motif:HMM:NF013094.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HNX48113.1"
                     /translation="MGPIRPGERDEDRHDRTKLIPWVDMERVRSAKVLVVGAGALGNE
                     VVKNLVLFGFRQVDVMDMDSVVRSNLSRCVLFREGDQRSGKGKASLVAERARELDPES
                     LVKAMEGKVQSLEPTDMGRYDVILGCLDNVAARLHLNANSYHARVPYVDGGTSGFRGR
                     VQAVVPPLTPCLQCGMNRSHFKVMERRFSCTGQDTVFYQPKMAAEITTTSVIAAVQVR
                     EAVKILSGRTAIAHVMHYDGLEGTSEVFTLDVDPGCPNHSVGRLS"
     gene            10506..12632
                     /gene="ppk1"
                     /locus_tag="PKM11_06115"
     CDS             10506..12632
                     /gene="ppk1"
                     /locus_tag="PKM11_06115"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: protein motif:HMM:NF003921.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HNX48114.1"
                     /translation="MPARKSSADRKTAAGKSKSKKQSGDSPFINREISWVRFHKRILE
                     EAQDTTHPLLERIKFLAICGSNLDEFFMVRVSGLKRQLKKGALEAPPDGLTPLEQLET
                     INQELLPLLEAHGKLWYDDLLPKLRTAGITIHRIEELDATKRKELRDYFERMIFPALT
                     PLALDFNQPFPFISNLSINLAVSVRHPQRGDRYARVKVPLDLFPRFVPIPGTAPGRTQ
                     NFVLLEDLVAENVDLLFPGMKVRDVHMFRITRDADIEITTDEAEDLLTAIEESVETRR
                     VGSPIRLEVDNDMPDKLADLFTTKLGLHPLMVFRSPAPLSLVGFWDLLSLNRPDLKDL
                     PFLPYVPGDLVPEKSLMAAVEHRDRLFYHPYDSFVPLVTFLKQAANDPQVLAIKITLY
                     RIDKHSPIIDALMEARENGKAVAAVVELKARFDEENNIVWARALENAGVHVVYGLLDL
                     KVHAKLLLVVRKKGNSIVRYSHMSSGNYNAQTSRIYGDIGYLTADPDIGADVADLFNY
                     LTGYSHKESYRKLLVAPVTLKDEMIARIDREATRHREHGDGYIGFKLNGLLDPEIIQA
                     LYRASRDGVRIDLNVRGLCALRPGVKGLSDNIKVNSIVGRFLEHARIYYFRNGGEEEV
                     FLGSSDMMPRNLKRRVEVLFPVLDAGYRRLLVDEILPIHLKDNVKSRDMLPDGTYVKR
                     KAAKDEAKVDSQDWLIRNRGSWHREE"
     gene            12638..14782
                     /locus_tag="PKM11_06120"
     CDS             12638..14782
                     /locus_tag="PKM11_06120"
                     /inference="COORDINATES: protein motif:HMM:NF017085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcE family phosphodiesterase"
                     /protein_id="HNX48115.1"
                     /translation="MDDLCVYGRRATAQRLTAFLAEVDGVRLGEDIECVHRMRVASRR
                     LRSALRIFGECFKGKKAKKWRREVRQVTSSLGEARDLDVQMELLGAIGKNWDGEESVG
                     LSLIIEMLRCRRASLQPDVVSLMDTIVGAGPFQEMRSELADAVEWNGDPSLLYPYAFG
                     HAAVAVEELMEHSHSVPVYEDWQGHHALRIAGKHLRYALEAFREAYPDGLDKDLRTLK
                     KLQDTVGELHDCDVWLQRLPSLREEAPAAIKAIDRLQSTFESRRRELHGKLVTQWSAL
                     LQDRFLFRLLDKLKGRPLVEVCPVKVALISDVHGNVHALRAVMEHARTNGATAFLNAG
                     DAVGLPHPVEAIQLLMDKDVISVMGNLDRASLKVAAGKKVRDRQLEMATEMLDKSELE
                     WLSSLPEDLRLDVCGRTVLVTHASPGQEAEKLTPNTPENRLRHLAQSTGADIVVTGHS
                     HIPMVRECVGTMFINPGSVGRPRDGSEASYALLDLPSLNVKLFRVSYDAKGVADELRS
                     QGFQDLPKELENGRTKDLVAAAGTWAERFHKDRQHAEQVRSLSTLIFDRTHGLHRLEH
                     RDRELLEMAAMVHDVGISEGAEGHQRRALDIVMKADLPLEEVERRMLACIARYHGLRS
                     PRREDRVFKGLTPSERRRVTKLSAILALADGLDRSHASLVGGLEVTVRRKAVKLTISG
                     PGDLSSEKEWGSRKSAQFARAFGREVTINDRT"
     gene            14769..16328
                     /locus_tag="PKM11_06125"
     CDS             14769..16328
                     /locus_tag="PKM11_06125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA phosphatase family protein"
                     /protein_id="HNX48116.1"
                     /translation="MIEPEKGRVVAFLDVGTNSIRLLVVRINPNRSFTVISEQKEMVR
                     LGEQEFSDGLLLESAMERAVRVIKNFYDLSKTYGASEFVAMATSATREASNRADLVDR
                     VKEATGLELQIISGMEEARLIYLGVSSGHHIGRKVALFLDIGGGSTELALGDQNEYSY
                     LESLKVGAIRLTTMFVKKPEAPVPEDVLSKMRKYVKSSLVRAKKEILQSKVSLVFGSS
                     GTVVNLGEILLRQDSSSRPGVIRLPQLRKLVLHLAGMDLAARRKVPGMNPERADIIVA
                     GAMVLETLMEELKLSEIAVSQRSMRDGMLQDYLGGLEEFPGFRELSVRERSVIQLGRA
                     CSIDEEHAQRVTSIALELFDSATKKGLHTLGKKEREMLHHAAFLHDVGDFISFNDHHL
                     HSHYIICHADLLGFSSREVLLIANIAKYHRKRTPKMRAADLRELDEEDQRVVILLSTL
                     LRMAESLDRSHSNLVQNVRFSKVTKRSVKLIVTASGDPQLEMWRMEEDRKAFNKAYGR
                     NLTVVLNNIEG"
     gene            complement(16378..16602)
                     /locus_tag="PKM11_06130"
     CDS             complement(16378..16602)
                     /locus_tag="PKM11_06130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48117.1"
                     /translation="MVMEKVSLDKAKDIAKKKGLKPGRVKGTNGVQFTKGNNARLEIV
                     SWEEFEKTLLKRGLAVFESGGWMKIMKKTK"
     gene            16858..18153
                     /gene="glmM"
                     /locus_tag="PKM11_06135"
     CDS             16858..18153
                     /gene="glmM"
                     /locus_tag="PKM11_06135"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: protein motif:HMM:TIGR03990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HNX48118.1"
                     /translation="MGLFGSSGIRGLIGKDIDAELGVRIGRAVGSLFGTVVIGKDPRT
                     SGDLVVSALIAGLIEAGAEPYRAGMVPTPTLACAASHFDCGLMVTASHNPPEYNGVKM
                     WNQDGSAFDGEQTAEVERLIAEGGRKAPWDEMFSERPWESAIDEHILTIMEEVGPVER
                     SIVLDCGCGATGPVSPRLFRDLGCSIVTLNANPDGRFPGRPSEPSEANLKDLMSLCKA
                     KGVAGIAHDGDGDRMVAVDEDGRYVSGDRLLALFASLLQVKDMAAPVDASMVLDDIVG
                     RPIVRTKVGDMFVSEALKKKGLPFGGEPSGTFIFPSVNYCPDGMLAGAYLLKLLDGRP
                     LKEVVGELPIYPSVRDSFSYDPSDRRKVKEKLAEEMSSIDGELTTVDGFRVDLGHGWL
                     LVRLSGTEPKVRLTVEARNQKDLEAIAEMARARIRKALG"
     gene            18200..19426
                     /locus_tag="PKM11_06140"
     CDS             18200..19426
                     /locus_tag="PKM11_06140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HNX48119.1"
                     /translation="MKALILAAGEGTRLRPLTTNIPKPLLTVAGRPYLAHLVQALRDA
                     GIQEQVILVGWKANRVKEFFGDGKQMGVELSYLEQKERLGTANAIGVAEGLMDGDFVC
                     VNGDVVMAPEAVAEMVSEFRKDRRPFMGVVEVPEPQRFGVVQHDNGKLVKIIEKPANP
                     PSKLINGGFFGLTDEVFDHIRKTGRSPRGEYEFTDTLNMMAAQTEVAVRKINGEWMDV
                     GYPWELLRANEYLMGRLKRDVRGTVEEGAVLKGVVVVEEGALVRSGSYVEGPVYISKG
                     CDIGPNCYLRPFTCLGEAVRIGSSVEVKSSIVMRRTHIPHHNYVGDSIIGERCNFGAG
                     TKVANLRFDDRTVRVTTKGQMLSTGRRKLGVIMGDDVKTGINAMIEPGTVIWEGTVVG
                     MGARARGNIGPHSKVF"
     gene            complement(19423..19800)
                     /locus_tag="PKM11_06145"
     CDS             complement(19423..19800)
                     /locus_tag="PKM11_06145"
                     /inference="COORDINATES: protein motif:HMM:NF025819.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HNX48120.1"
                     /translation="MLKVRGIDRALLEMINEAARDSLPNEFVAMLRAEDGIIQELLLL
                     PGTLQGEDSATLMMHMMPIDFSVVGTVHSHPGYSNRPSREDLELFRRYGYVHIITCLP
                     YDEGSWRAYDGQGRRMQLPVVEL"
     gene            complement(19794..20603)
                     /locus_tag="PKM11_06150"
     CDS             complement(19794..20603)
                     /locus_tag="PKM11_06150"
                     /inference="COORDINATES: protein motif:HMM:NF039482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HNX48121.1"
                     /translation="MKFGMSVNMNIPDAPRMAKRTLELLKGHEVLLEKEMAERFKTKG
                     LLLDEMDVDMMVTVGGDGTILRALQHNKAPILGINAGDLGFLTVASEEELEEGIDNVL
                     RGNYELEERIKLQTTVGGKRMLDAMNEAVLHTAHVAKIRHFQVFVDGEMAMNVRADGI
                     VVATPTGSTCYAMSLGAPLIDPRVEALVIAPMAPFKFSTRPVVVPASSRITVQVVRPK
                     ECVVVVDGQQELLMAGNETVEFKASPDRARFVSFGKGFYARTREKLMGNLC"
     gene            complement(20600..>20895)
                     /locus_tag="PKM11_06155"
     CDS             complement(20600..>20895)
                     /locus_tag="PKM11_06155"
                     /inference="COORDINATES: protein motif:HMM:NF012673.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0046855 - inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HNX48122.1"
                     /translation="ASANGVLRKARRTRSMGCSSLEMCLVAAGLADGFYLNSEVYQRA
                     LRVVDIAASALILREAGGELYDLDGNVLDMALDLEVRANCLAAGDAAMVRWLL"
BASE COUNT         4268 a         6125 c         6248 g         4154 t
ORIGIN      
        1 tgatgacccc gatcaccgcg tgcgtgttgt gcgccttggc gtcaatgacc ggcgccacgc
       61 tcaggcaggc ggaaacgccg cagacgctgt tgcccgtgcc aatgagcgca gaggcgtcct
      121 tctccagccg caccttcctg ccaaggaaca aggagaacca gaccgtgaag gccatgaccg
      181 ccaggatgat cacaatgccg accggtgatg ctttggacag cacgtccaag gtcactcgcg
      241 cgcccatgag cacgatagcc agtcgcagca ggaatcgacc ggcgtaggct ccacctgggt
      301 agataggcga tacgttcacc agcagaccga tgagaagcgc cagcactatg ggtccgacct
      361 tgaacaagaa ggacgccagg ggattatccg cgaacagatt ggagtccaac agcctggggc
      421 cgccttcgaa cagggtgccc ctggtgacca gataggacgc tacggccacg atgaggcaga
      481 acagcagccc tggaacctcc ttgcgaccga cccgcagata cagcttggcg tcgtctacgt
      541 atgacatggg acctgaggtc gagatggtca acggtcttaa atgatttctg ccccgctcaa
      601 ttcgattcct gcctgcggcg tattccgtag gcgaccagaa tgatcaggag ggttatggcg
      661 attatcgccc agatcagggg ccagtttatc caagtatagg tcttgaactg ctcctcgagg
      721 gaaccgacgg ttacgtggtg ctgacctttg tggaccccgt tgaactggaa ggtcagctgt
      781 tcgctctctc cagcttccag gtacacatcg acggtatcta cgaccctgtc gtctagaacg
      841 atattgatcg tgaaattgcc tggggcgttg ccgacgttgc tgacgttgag gctcacgctc
      901 gccttgtagt tgtacttgat gaacagcgga agcacgttcc accagaaaac cttcttggtg
      961 cctttgaagg tcagctcgct gatctccagc aaggcgtact cgtccctgtc gtcatacgcg
     1021 ccggccgcgt agctgccggt gccgattata tcggcgtagg cgtaccagga gtagaacgga
     1081 ccggtctcgt tgagcctgac ccagacacca tcgaccagct ggtataatcc tggaacgaaa
     1141 ccttcgggaa gcgcttccgg gtcgaaaccg attatcagcg atgcgccaga cgagaagctt
     1201 acgttcgttg agacgttgtt ctggtcgaag gccgagatga cgtaggtggg gctgagcgcc
     1261 gtggcgttgg ttccgttcag aacgtcctcc tgctcggcct cggtcaccac cagccactcg
     1321 ggcaccgtgc cattctcggt cagtatctgc gtaccggcgg cgaactccag taccaccgtg
     1381 ccattggcgt tggtggcctg gaacgcttcc tgcacgtacc cggtggcgtt cagggccacc
     1441 acggtcaatg tgcccagcac gtcgatcaca agccaggaga cgccatcctc aggaccggtg
     1501 gcggtcatca aataattaat ggtgaagctc aacccgtcgc cctgcgcctc gttctgcggc
     1561 gcaccgctgt caaagaactc ccaggcccag gtgaggttga tggtctcccc tgctttcagc
     1621 ggtccgatgc agatggagcg gtccaacgac gttcggggca tgtccgtgaa cggagcgggg
     1681 aagctgatgt tgctggacat attaacggac gagggagcaa gtaggaagtg ctcggcaagg
     1741 tgccttccgt ccgtcccgcc gtcagtttcc acgacatcgc tgaaccagat ggtcacgtaa
     1801 ccgtcgatcc tcccggcgtt cctcagctct acgagctccg tgccgttatc gccgggaacg
     1861 atgttggcga tcgtccaggg agcgctgccc gagccgccga tggtgaggtt catcaccccg
     1921 tcaccggccg agaccggggc ggacatgaac aggagcggtg ctagcatcga taccacgaga
     1981 agtagcgccg cgagcgaccg tcctgcccga aggaaagaac ggttcaactc agaaccccct
     2041 gtagtagaga cgtacttcgt acaagatggg ggtagaggtt gtgacggtgg tcgtcatatc
     2101 cacccgccat tgcacgtatt gaccggttat ggtgcttatg gaacttccag tcaccgtggt
     2161 ccaggccacc cctgtcagat cccaggaacc gttgaccccg gtttggttgt tagggtcgtc
     2221 aggagtgggt atccatgtgc gggtgttaga tgcccgtacc ttgaatgaga tgcttgtacc
     2281 ggatggcacg gtataatcgg cgaacagcga atctaatttc atgttcgcct ttcccgtgtc
     2341 gtgaacgctc gaaacgagat agccgctggg agcgtaacct gtggcgaaag caacataaag
     2401 caaattactc ccgaaattag ctttcacggg tgagggcata ctggtcatcg tggcccaggt
     2461 ccgaagcgtg gagttgtact tcaacagaat gttggtgttg cctccggcgg tcacgaacgg
     2521 ccggatgttg tcataggcca gatcggaacc tacattgagt ttgctgttct tcggaacaag
     2581 cccgagttta gtgaaggcct tggtcgtaat actgtattga tagacctccc gattatcgcc
     2641 gccgcggccg atgagcagat aggccccttg accatgggtg atcgacacac cgaggccaaa
     2701 acctttattg gccggattgg tgatcgttat cggggtcaca gttattccat ccaggctcac
     2761 ctggtagaac acgttagtgt tggtggggga ggcggtggac cggacgatgt aaatgaaccc
     2821 caagtacacc accatcgatg cgccgtatgc gttggtctcg cctattttcg gtaaggtagt
     2881 ggttagggtc caccacgtat cgttcgacgg gttgtatttc cacagggttc cggtattacc
     2941 accttgcagg gcgtagaaca tcccgtcatt gtagttccgg aggaaaccac cagcacctac
     3001 cggcccaggc gtgtccgctc tcttggacca gttgttgtac tgggtgtcga acctccagaa
     3061 gtgacgggtc ccgcccccca tcatcgcgta gatgtaacgg gattcgtcga aggccatgga
     3121 tccgccgtaa ccgacgttcg ccgggacgtt ggccctttgc gaccagttat tggattctgt
     3181 ataataacga tagaagtccc tggtattacc gccagccaga aggtataggg atgacatggc
     3241 ggtctccttc tcggccaggg tgacgtctcc agggctctcc agggtgtgca cttcgaactt
     3301 ggtggtattg ttgtagaaat cgtcctcggt ggtggacttc cacatcttag gagtgtacgc
     3361 gctaatctta ttgttagcgc tgttctcgac gtcactgaac gcggcgaaca atccagtgtt
     3421 caggaacgcc accacgataa gtaatgagac tatggtcagg aggcgtttct tcgagatcat
     3481 tgctcgcccc ctgaggtaga gtcgtccttc tccctatcct cgtacaatcc caacaggagc
     3541 atagctgcga taaggacgaa aatcagcacc cagccgtaga cgctcttcag gaagagcacg
     3601 gcgtgccctg cgtaaggtac gaccagaccg acctcggtga ccacatcgtc atacgttatg
     3661 gtgtaggggt cggggtcttc gttcgcatct ccttgcgtct ggatccagcc cgcctcggcg
     3721 ttgatagcaa tcacccggtg acagatgagg atgccagaat gccggaagac tatgatgtcc
     3781 ccgaccttga tgtcctcgtt atcaacggag ctagagatcg ccaggtcccc gacctcgatg
     3841 gccggggaca tgctgccgga acggaccgga tcaaaacgga acccgatgac gggggatacc
     3901 gccatgaaga gcaccagagc taacactgcc actgatatgg ccgtgcctac actggaccac
     3961 ttcatgcttt caccctccgt caaaggtaag gagattgttc attcacttgg ttcggtttgc
     4021 gctcacacct gggtaccggc gttgccgtca gcgtcctggt tcagtacgaa ccgcagaccg
     4081 aaggtcacga tgtcgccctg gatctggtta tcggcgctgg tcggcacgga gaagctcaca
     4141 gtgaaagtga gggtgctacc cgctgccata gggatgttgg ccaagttcgt catggctcca
     4201 ttcagcagcc ctgtgtatgt gaatgtcccg gcggttatgg ttatggacaa aacctcagac
     4261 aggtcaccac ccgtaccagt ggcgacacca gcaacaccat tggcgttacc agtagtaact
     4321 agttctggct cggtgtcggt tccgttggtg tcgacaattt ggacgatggt caccgtaaga
     4381 agcccggcca ttgagccatt attcttcagg gttatgctcg tgggtatagc ggaggtgaaa
     4441 ccggggtaca cgccactctg agtgaggtag gcggttacgt tgcttgcggg actggttacc
     4501 tggaggtcca aagttgctgc ggtaaccttg ttaccggcgt tgttctcaac gtcgttgaag
     4561 taggcgttta cgccccagct cgcgaccagg gccacgacga ccaaggccag cgcgctgatc
     4621 attatccttt tcttttgcat tttgatatct ccttatagtt tatcggagta ttaaactccg
     4681 ttaaaatccc ttaagttgcg tctcacctat aataagattt tctgtcttat tccgttttgt
     4741 gattttacct ttgaacatct ggacagggta tcgtatgtta aaccgatgat tcgtatcgta
     4801 cctaaataac agctcactat gatccgttaa tgttaaataa aagcgatcga ttttaaataa
     4861 ttatcaatta atcacttaat aaacctataa aaaatagttt tatggaattg ttaagtcgag
     4921 attaatagaa taaatgaaaa gtggtgggtc tgtccgaatt tgaatcggag tcacctgcac
     4981 cccaagcagg aaggattcca agctacccca cagacccatt ttgtaaaggg gttataagag
     5041 gtttaaccca gggggatcag ctcaccgagc aggtccgagt gggaaatgat catacggcgg
     5101 cagcagtacc gtttgatgtc cagatcgtcc agcacttcct gggggttctc ccccatctgc
     5161 accctcttga cgaaggtctg gtaggagctg cccaccacct tgccgcacgt gaaacatctt
     5221 accggtatta tcatttctgc tcacctgtac gatttttgcc tcttcttcct ggcgccacga
     5281 cccagcggct tcttcgggag cttgcggcgg acgtcgctga tcagcaacga cctgtcgaag
     5341 tgcttgaagg cgagcttcag ctcctcgtca tggaagaact ccacgatggc cttggcgatg
     5401 gcggtacggg tggcttccgc ctgacccatc acgcctccgc cggacacgct gacgtcgata
     5461 tcgatcttgg cggccttctc gggcaccaag gtcaagggct cagccatctt taaccgagcc
     5521 agctcagggg tgacgatgtc cagcggcacg ctgttgatgc gcaccttgcc ggtaccctcg
     5581 cgggccaccg cgcgggccac cgccgtcttc ctcttaccac tggtattgac aacttcggac
     5641 atatcacatc accctcgagc ccaggaactc ggctatctgg ctgagcgtga cgtattgggt
     5701 cagcccggcc ttgatcgcca cgtcgacctt ctccttggga gagtcgacga actccttcgg
     5761 tacaccaacg aataccttca gcctcctgta ggccatcctg ccggaggtgg tcttccaggg
     5821 gatcatcccg cgtaccgtcc tcttcattat gaggtcggcg cggcggggga agaacgggcc
     5881 gctcttgacg ttgcccaggt ccttcttctg cttgtaagcg gcgagcacgg cgtcgcgctc
     5941 cccggtgatt atgatcttct cagcgttgac gacaacgatc tcttcgccct tcatgatcct
     6001 cttggcgatc acggtggcga gccttcctgc gatgtggttc tcagcgtcta tgattgcaac
     6061 catttgctca cctcattatc ttaacgccag ttccctgggg catctccttg accagttcca
     6121 tgatggtcag gttcttgccc ccggcggcct cgatcttcat cttggcggac tcggagaacc
     6181 cgtaggcggc tacggttacc ttcttgttga tcgctccaga ccccaacacc tttcccgcta
     6241 cgactatgac gtcgccctcg gaggcgtatc gctcgatctt gctcagatta acctcggccc
     6301 aattggcctt ggctttttcc aatcttagag caatgtctcg ccagatcccc gcaccgctgg
     6361 acctcgactc cgccttcagg gcggatatca gggtcaagag attggggtca gtctttgcat
     6421 gtgccatatt ctgactctcc cgacattggt aagcccctct aatagggagg ggtattaaat
     6481 acctttgcca tccaagcgga cgctcgtcag aggccttgaa cgaactgctg gctggagaac
     6541 ttggcggccc ggatacctat ccatataata accgggtact tatgtcctac cgggcgggct
     6601 tcgagcgctc catactataa tattaacgct tataaattaa atttagatag cccttatata
     6661 tctcgttgga catatggttt agtttgctcg gggtttctga tgattagatt tggtccagct
     6721 ggtattccac tttcttgtaa gggtcgcact ttgaaggacg ggatcgagga cgttcacggc
     6781 ctcggtctnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngg ggtcatgggg
     6901 gccgagctgg acgtcgcgct gtccatgcac accccgtact acatcgacct ggccggcgag
     6961 ggcgacctca ccaggaagag catggactcc atccgctggg cgggcatgat gacccaggcc
     7021 atgggcggga acatggtcgt cacccacatg ggcctttatg gcaacatcag ccaccgcgag
     7081 gccgcagaga acatctccga ccgtttggag gagatagtca cctggtggga gaagaacaag
     7141 cttacgcccc gattgggact cgagacgtcg ggacgcaagg aggtgttcgg cggcctggac
     7201 gagatcgtgg agctgtgcga taagttcgat gtcctgaccc cggtggtcaa tttcgctcat
     7261 taccacgccc gcaacaacgg catgctgcgt gagccggagg atttcgccga ggccttcgac
     7321 caggtcaaga gctacgtcgg cgatctgcat tacactcact tctcaggcgt ggagcacgag
     7381 ggcggtaacg aacggagggt caccccgatc aagaagggcg atctgcgctt cgaacccatg
     7441 gccgagttcc tggccgatgc caacttgaac gccacgatca tatccagctc cccgctcctg
     7501 gagcacgacg ccatgtacat gaaggtcatt tacgaacgag tgatgaccaa gagggtgacc
     7561 aaggacatca aggtcaagaa gggcaagggt gccaaggacg aggatgacga gtgaaggaga
     7621 ccaccgccta cattcttgag gaggtcaggc ggaccatcga gaaggtggac gagccgttga
     7681 tagacgatat cgtcaccacc ctcgccgccg cccccaagat attcatctac ggcgtcggac
     7741 gctccggact ggtcggagag gccttcgccg cccgtctggt ccagatcggc ctgaacgttc
     7801 atttcgtcgg tgacaccacc acccccatcg tggagaaagg ccacgtcgtt ctcataatat
     7861 ccaacaccgg ggagaccatg tccgcggtgc agaccgccaa catcgttcgc cgtctgggag
     7921 cggtggtgat cagcgtaact ggcagcgccc actccaagtt aggcatagcc agcaacatgg
     7981 tgatggagct cgtccaaccc cgggacgaac gtaagaagaa gaatgcgccc ttgggtacga
     8041 tattcgagct gtccagcatg gtgatgctgg actccatggt gccgctattg atgtccaagc
     8101 tggaccagga cgaggcgtcc ctgcgccgaa ggcacgccat ctgggtctga tcaggtcctt
     8161 atcttcttag gccgcacgct ctccccgtaa taggggttct ggaactcgtc ccagtacacc
     8221 acgaactttt tgcgacgaac gtcaccgttg gagaggcaga aggcgtccat ctccttacgt
     8281 ataggatcga ccaccagggc ggtgtgatac ggtcggtcga acatcccgcg ctgggtcgcc
     8341 acgtccgtgg atgacaggaa gcaaccgtgc ccggggtggg aatggtacca gcccaccagc
     8401 acgtagcgga agcgggcgga ctccagcgag gcgaacagcg attcaaatcc atccggatcg
     8461 aacctcacgc tcaccgatgt cgcttccaga tcggtggtgg ccacgtcccg caccacggtg
     8521 tattcgatgc cttggtgcgt gaacacctcc cccaacagga agcccatgac ctccagtccc
     8581 gccttgacct gggacagggc gtggttgcgc accttctcct cggcggtctt gaagaggtac
     8641 atctccgctg ccttactatc agaatataac gaggcggcct ccttagggag ccatttgtgc
     8701 ggcagcgttc tctccttgac cggagggatc atctcttcca cctccaggtc cttgccgctt
     8761 atgatcaccg gagctctctt cactggccca ccaccttggg agcgggggcg actatcaccg
     8821 gcggcgtgcg tcggggtgtg gaattgaagt actgggcggc ggcggtgcag gtatcggtgc
     8881 cgaacggact gttgccgttc ggtgagagca gtagcgactc cagccccttg atgaaattga
     8941 atagcgtgga attgaaggac cactccgaaa gaagtttgat gcagacatga ccgccgtcct
     9001 cgggcatcat gatgttagga tgatagatag gggtcttcca gatcaccaaa ggtttttcga
     9061 acggatactc gcgtccgatg atcaggtcca gccggtggct gtagcgatac acgagcttgc
     9121 cgttctccat gaccgggccg ggaatgcctt ccatgcccac ctccaccctc agcggtaact
     9181 tcgtcagtcg ctcctcgcta aggtcaaact cctgcggtag gtagtgatgg cacgcttcca
     9241 gctcgttcct caatcttatg taaagtatct ccaggggcag ggtcatctgt tcccgccctc
     9301 ggggtcaggg atcagctcca gctcctcgtt ggcctggatg tccaattcct ggaccttctg
     9361 ctgccccctg agcaagcgtc tcccttttcg tatgacatag gcgccggggt ccttctccca
     9421 gaatgctgag acgccctcga tgatctcctc cacggtgttc tccagttcca gctccatgtc
     9481 gaccgtggcc ccggtctccg cgttcctgac ccttatcctt accaccattt ttatcgcccc
     9541 ggtcaatccc tgggaaggga gtataatcct ttcccttaga gttagcatta tgataatctg
     9601 cctacggaat ggttcggaca gcctggatcg acgtctaacg tgaacacctc gctcgttcct
     9661 tcgagaccgt cgtagtgcat gacgtgcgct atcgccgtcc gtccggacag gatcttgacc
     9721 gcctcccgca cctgcacggc ggctatcacg ctcgtagtgg tgatctccgc cgccatcttg
     9781 ggctggtaga acacggtgtc ctgcccggtg cagctgaagc ggcgctccat gaccttgaag
     9841 tggctgcggt tcatgccgca ctgcagacag ggcgtcaacg gcggcaccac cgcttggacc
     9901 cgccctcgga aaccgctcgt ccctccatca acgtacggta cccgggcgtg ataggagttg
     9961 gcgttaagat gcagacgggc ggccacgttg tcaaggcatc ccaggattac gtcgtaccgt
    10021 cccatatcgg tcggctcgag agattgcacc tttccctcca tggccttgac cagagattca
    10081 gggtccagct ccctggccct ctcggcgacc aatgaggcct tccctttccc ggaccgctgg
    10141 tcgccctccc ggaaaagcac gcagcggctg aggttggaac ggaccacgga atccatgtcc
    10201 atgacgtcca cctgccggaa gccgaacagt accaggttct tcacgacctc gttgcccagc
    10261 gcccccgctc cgaccaccag cacctttgcc gagcgaactc gttccatgtc cacccagggg
    10321 atgagcttgg tccggtcgtg acggtcctcg tccctctccc ccggtcggat cggccccatg
    10381 cccggaacga ccgtttcctg actataaaaa aatggaccgt accagtacat attatgatat
    10441 tgacgagcgg gaagactggg cggtaacctc atatatactg gaggtaggat gttataggga
    10501 agcctatgcc cgcccgaaag agcagcgcag accgtaagac cgccgctggt aagagcaaat
    10561 ccaagaagca gtccggggac tcgccgttca tcaatcggga gatcagctgg gtaaggttcc
    10621 acaagcgcat actcgaggag gcccaggaca ccacccatcc gcttctggag aggatcaagt
    10681 tcctggccat ctgcggcagc aaccttgacg agttcttcat ggtccgggtg tccggtctca
    10741 agaggcagct caagaagggc gccctggagg cgcctccgga cggcctgacg ccgctggagc
    10801 agctggagac catcaaccag gaactgttgc cgttgctgga ggcgcatggc aagctctggt
    10861 atgacgacct tctgcccaag ctccggacgg ccggtataac catacaccgc atcgaggagc
    10921 tggacgctac gaagcggaag gagctgcgcg actacttcga gcggatgata ttcccggccc
    10981 tcacgccgct ggcgttggac ttcaatcagc cgttcccgtt catatctaat ctgagcatca
    11041 atctggccgt cagcgtgcgg catccccaga gaggggaccg ctacgcccgg gtcaaggtcc
    11101 ccctggacct cttcccacgc ttcgttccga tcccgggaac cgctcccggc cgaacgcaga
    11161 acttcgtact gttggaggac ctggtggcgg agaacgtcga tctcctgttc ccgggcatga
    11221 aggtccggga cgtgcacatg ttccgcatca cccgcgacgc ggacatcgag atcaccaccg
    11281 atgaggcgga ggacctgctg acggcgatag aggagagcgt ggagaccagg cgcgtcggtt
    11341 cgccgatacg gctggaggtg gacaacgaca tgccggacaa gctggccgac ctcttcacca
    11401 ccaagctcgg actgcatcca ctgatggtgt tccgttcccc cgccccgctc tcgttggtcg
    11461 gcttctggga ccttctctcc ctgaaccgcc cggacctcaa ggacctcccg ttccttccct
    11521 acgtgccggg ggacctggtt cccgagaaat cgctcatggc cgcggtggag caccgggaca
    11581 gactgttcta tcacccgtac gattcgttcg ttcccctggt caccttcctc aagcaagcgg
    11641 ccaacgaccc ccaggtgctg gcgatcaaga tcacccttta ccgcatagac aagcactccc
    11701 cgatcatcga cgccctcatg gaggcgcgag agaacggcaa ggccgtggcg gcggtggtcg
    11761 agctaaaagc acgcttcgac gaggagaaca acatcgtttg ggcccgggcc ctggagaacg
    11821 ccggggtaca cgtggtctac ggactgctgg acctcaaggt gcacgccaag ctgctcctgg
    11881 tggtgcggaa gaaaggcaac agcatcgtcc gctacagcca catgagctcc gggaactaca
    11941 acgcgcaaac gtcccgcatc tacggcgaca tcggttacct caccgccgac ccggacatcg
    12001 gggcggacgt ggccgacctt ttcaattacc ttaccggtta ctcgcacaag gaatcctacc
    12061 gcaagctgct ggtggccccg gtcaccttga aggacgagat gatcgcccgc atagatcgcg
    12121 aagcgaccag gcatagggag catggcgacg gatacatagg gttcaagctc aacgggctgc
    12181 tggacccgga gatcatccag gccctctacc gggcctctcg ggacggcgtt cgtatcgatc
    12241 ttaacgtgcg cgggctgtgc gccctgcgtc cgggcgtgaa gggactgagc gacaacatca
    12301 aggtgaacag catagtcggg cgcttcctgg agcatgctag gatctactac ttccgcaacg
    12361 gcggggagga ggaggtcttc ctgggcagct cggacatgat gccccgcaac ctcaagcgga
    12421 gggtggaggt gctgttcccg gtgctggacg cgggataccg ccgcctgctg gtggatgaga
    12481 tacttcctat ccatctgaag gacaacgtga agtcccggga catgcttccc gacggaacgt
    12541 acgtcaagag gaaggccgcc aaggacgagg cgaaggtgga ctcccaggat tggctgataa
    12601 ggaaccgcgg gtcctggcac cgggaggagt gaggccgatg gacgatctgt gcgtctacgg
    12661 acggagagcg accgctcaac gtctcaccgc cttcctggcc gaggtggatg gtgttcgtct
    12721 cggggaggac atcgagtgcg tgcaccgcat gcgggtggcc tcccggcgcc tgcgctccgc
    12781 gctgcgcatc ttcggggaat gcttcaaagg aaagaaggca aagaagtgga gaagagaggt
    12841 gcggcaggtc acctcctcgc tcggtgaggc gcgcgacctg gacgtgcaga tggagctgct
    12901 gggagcgatc ggcaagaact gggacgggga ggagtcggtc ggcctttcgc tcatcataga
    12961 gatgctgaga tgccgcagag cgtccctgca accggacgtc gtgtcgctga tggacaccat
    13021 cgtcggtgcc ggtcctttcc aggagatgag atcggaactt gcggacgcgg tggaatggaa
    13081 cggcgacccg tccctgctct acccgtacgc tttcggacac gccgcggtgg ccgtggagga
    13141 gctcatggag cactcccatt ccgttccggt ctacgaggat tggcagggac atcatgccct
    13201 gcgcatagcc ggaaagcacc tgcgctacgc cctggaggcc ttccgggagg cttacccgga
    13261 tggcctggac aaggacctga gaacgctgaa gaaactgcag gacacggtcg gcgagctgca
    13321 cgactgtgac gtctggctgc aacggttgcc ttcgctgcgg gaggaagcgc ccgccgccat
    13381 caaggccatc gaccgcctgc agtcaacgtt cgaatcccga aggcgggagc tgcacgggaa
    13441 gctggtgacg caatggagcg ccctgctcca ggaccgtttc ctgttccggc tgctggacaa
    13501 gctcaagggc cgcccattag tggaggtgtg cccagtgaag gtggcgctga tatcggacgt
    13561 gcacgggaac gttcacgcgt tacgggcggt catggaacac gcccggacca acggagcgac
    13621 ggcgttcctg aacgccgggg acgccgtggg cctcccacat ccggtggaag ccatccagct
    13681 gctcatggac aaggacgtca tcagcgtcat ggggaacctg gaccgcgcct cgcttaaggt
    13741 ggccgcggga aagaaggtca gggaccgcca gttggagatg gccaccgaga tgctcgataa
    13801 gagcgaactg gaatggctaa gctccttgcc ggaagatctc cgcctggatg tctgcgggcg
    13861 taccgtgctg gtcacccacg cctcccccgg acaggaggcg gagaagctta ctccgaacac
    13921 accagagaac cggttgcgcc atctggccca gtccactggc gcggacatcg tggtcaccgg
    13981 tcactcacat atcccaatgg tcagggagtg cgtgggaacc atgttcataa acccgggtag
    14041 cgtggggcgc ccccgggacg gatccgaggc ctcctacgcc ttgctggacc ttccgtcgtt
    14101 gaacgtgaag cttttcagag tgtcatacga cgccaagggc gtcgccgatg aacttcgctc
    14161 ccagggattc caggacctgc ctaaggaact ggagaacgga cggaccaagg acctggtggc
    14221 ggcggccgga acctgggcgg aacgtttcca caaggaccgc caacacgccg aacaggtgcg
    14281 gagcctgtcg accttgatct tcgatcgaac gcacggactg catcgcttgg aacaccggga
    14341 ccgcgagctg ctggagatgg cggcgatggt gcacgatgta ggaataagcg agggagcgga
    14401 agggcatcaa cgaagagcct tggacatcgt gatgaaggcc gatctgcctt tggaagaggt
    14461 ggagaggagg atgctggcct gcatcgcccg ctatcacggc ctgcgctcgc cgcgccggga
    14521 ggaccgggtc ttcaagggat tgaccccctc ggagaggaga agggtcacca agctctcggc
    14581 catactggcc ctggcggatg gcctcgaccg tagccacgcc tccttagtag gcggactgga
    14641 agtgacggta cgcagaaagg cggtcaagtt gaccatctcc ggaccggggg acctctcatc
    14701 ggagaaggag tggggttcac gaaaatcagc tcagttcgcc cgggccttcg gaagggaggt
    14761 gactattaat gatcgaacct gagaagggga gggtggtggc cttcctggac gtcggcacca
    14821 actccatacg gctgctggtg gtgcggatca accccaatcg ttccttcacg gtgataagcg
    14881 agcagaagga gatggtccgg ctcggtgagc aggagttctc ggacggactg ctcctggaga
    14941 gcgccatgga acgggccgtt cgggtcatca agaacttcta cgacctctcc aagacctacg
    15001 gcgccagcga gttcgtggcc atggccacct cggccaccag ggaggcttcc aaccgcgccg
    15061 atctggtgga ccgggtgaag gaggccaccg gactggagct tcagataatc tccggcatgg
    15121 aagaggccag gctgatctat ctgggcgttt ccagcggaca tcacatcggc cgcaaggtcg
    15181 cccttttcct ggacatcggc gggggcagca ccgagctggc cctgggcgat cagaacgagt
    15241 actcctacct ggagagcctg aaggtcggag ccatacggct caccaccatg ttcgtgaaga
    15301 agccggaggc accggtcccg gaagatgtcc tctccaagat gcgcaagtac gtcaagagct
    15361 ccctggtccg ggccaagaag gagatcctgc agagcaaggt gtccctggtg ttcggaagct
    15421 ccgggaccgt ggtgaacctc ggggagatcc tgctccgtca ggactccagc tcgcgcccgg
    15481 gggtgataag gctgccgcag ctccggaagc tggtgctgca cctggccggc atggacctgg
    15541 ccgcccggcg caaggtgccg gggatgaacc cggagagggc ggacatcata gtggccgggg
    15601 ccatggtcct ggagacgctc atggaggagc tgaagctgag cgagatagcg gtcagccaac
    15661 gcagcatgcg ggacggcatg ctgcaggact atctcggcgg gctggaggag ttcccgggct
    15721 tccgggagct gtcggtacga gaaagaagcg tcatccaatt gggacgggcc tgctcgatag
    15781 acgaggaaca tgcccagcgg gtgacctcga tagccctgga gctgttcgac agcgccacta
    15841 agaaaggatt gcacaccctg ggcaagaagg agcgggagat gctgcaccac gcggccttcc
    15901 tgcacgacgt gggggacttc atctccttca acgatcatca tctgcattcg cactacatca
    15961 tctgccatgc cgacctcctg ggcttctcca gccgcgaggt gctgctcatc gccaacatcg
    16021 ccaagtacca tcgcaagcga acgccgaaga tgcgagcggc tgaccttcga gagctggacg
    16081 aggaggacca gcgagtggtg atccttctat cgaccttgtt gcgcatggcc gagagcctgg
    16141 accgttcgca ctccaacctg gtgcagaacg tgcgtttcag caaggtcacg aaacgctcgg
    16201 tcaagctcat cgtcaccgcc agcggggacc cccagctaga gatgtggcgc atggaggagg
    16261 accgcaaggc cttcaacaag gcctatggcc ggaacctcac ggtggtgctg aacaacatcg
    16321 aaggttgaaa aaagtaaaag gaaagttaag gggtttgact gggtaaaaag taagacctta
    16381 cttggtcttc ttcattatct tcatccagcc gccgctctcg aacaccgcga gacccctctt
    16441 gaggagggtc ttctcgaact cctcccagga tacgatctcc agcctcgcgt tgttgccctt
    16501 ggtgaactga actccgttgg tgccctttac gcggcccggc ttgagaccct tcttcttagc
    16561 gatgtccttt gccttatcta agctgacttt ctccataacc atggaacgac ctccgcgata
    16621 atcgaccaat ctggcctgtt atccagtaag taatggaaat actcgatata taatatttat
    16681 tacataaagg acggtgacca gtgtttattc ctcttatata gtatagggtg ttaacccctc
    16741 cccgcaccca gatttttatc ccttgggacg gtatgcctaa acgatgctgg ccgaatgact
    16801 ggccatgcct ggaaggacag ggattaaatg ccttagcagg gattacctgc cgatattatg
    16861 ggcctcttcg gttcctccgg catacgcggt ctcataggaa aggacatcga cgccgagctt
    16921 ggcgtgcgca tcggacgagc ggtgggcagc ctctttggca ctgtcgtgat aggaaaggac
    16981 cctaggacca gcggcgacct tgtggttagc gctctgatcg ccgggctcat cgaggccgga
    17041 gcggaaccgt accgggcggg catggttccc acgccgacgt tggcctgcgc cgcttcccat
    17101 ttcgactgcg gcctcatggt caccgcctcc cataaccccc cggagtacaa cggggtcaag
    17161 atgtggaacc aggacggcag cgccttcgac ggggagcaga cggcggaggt ggagagactc
    17221 atcgccgagg gcggcaggaa ggccccctgg gacgagatgt tctccgaacg gccgtgggag
    17281 agcgccatag acgagcacat ccttactatc atggaagagg tgggaccggt cgagcggtcc
    17341 atcgtcctcg attgcgggtg cggggccacc ggtccggtga gcccccgtct gttccgggac
    17401 ctgggctgtt ccatcgttac cctgaacgcc aatccagacg ggcgcttccc gggaagaccg
    17461 tccgaaccgt ccgaggctaa cctcaaggac ctgatgtcgt tgtgcaaggc caagggcgtg
    17521 gcgggcatcg cccacgacgg ggacggggac cgcatggtgg ccgtggacga ggacggccgc
    17581 tacgtcagcg gcgatcggct cctggcgttg ttcgcttcat tacttcaggt caaggacatg
    17641 gccgccccgg tggacgcctc catggtcctg gacgacatcg tcggaagacc tatcgtgcgc
    17701 accaaggtag gggacatgtt cgtatcggag gcgctgaaga agaaaggcct cccgttcggc
    17761 ggcgagccgt ccggaacgtt catcttcccc tcggtcaact attgcccgga cggcatgctg
    17821 gccggagctt atctattaaa attgctggac ggccggccgc tgaaggaggt cgttggtgag
    17881 cttccgatct atccctcggt ccgggactcc ttctcgtacg atccctccga tcgaaggaag
    17941 gtcaaggaga aactcgccga ggagatgtcc tcgatcgacg gcgaactgac caccgtggac
    18001 ggtttccggg tggacctggg gcatggctgg ctcctggtgc gcctctcggg aacggagccc
    18061 aaggtgcggt tgaccgtgga ggcccgcaac cagaaggacc tggaagcgat agccgagatg
    18121 gccagggcca gaatacgaaa ggccttgggc tgagcaggca tttaatagct gaccgccaat
    18181 ttcaatggga aggaattaaa tgaaagcgct catcctggcc gccggagagg gaacccgcct
    18241 cagaccgctc accaccaata ttccgaagcc gctgctgacc gtggccggca ggccgtacct
    18301 ggcccacctg gtgcaggcgt taagggatgc cggcatccag gaacaggtca tcctggtggg
    18361 ctggaaggcc aaccgggtca aggagttctt cggcgacggg aagcagatgg gcgtggaact
    18421 gagctatctg gagcagaagg agcgcctggg caccgccaac gccatcgggg tggcggaagg
    18481 gctcatggac ggcgatttcg tgtgcgtcaa cggggacgtg gtcatggccc cggaggcggt
    18541 ggccgagatg gtctccgagt tccggaagga ccgtcggccg ttcatgggcg tcgtcgaggt
    18601 cccggagccg cagcggttcg gggtggtcca gcacgacaac ggaaagctgg tcaagataat
    18661 cgagaaaccg gccaaccctc cgtccaagct gatcaatggc ggcttcttcg gcctcaccga
    18721 cgaggtcttc gatcacatac ggaagaccgg gagatcaccg cgcggagaat atgagttcac
    18781 ggataccctg aacatgatgg ccgcccagac ggaggtggcc gttcgcaaga taaacgggga
    18841 atggatggac gtcgggtacc cctgggagct gctgcgggcg aacgagtacc tcatgggccg
    18901 cctgaagcgg gatgttcgcg gtactgtgga ggagggagcg gtgctcaagg gcgtcgtggt
    18961 cgtggaagag ggcgccctgg tgcggagcgg aagctacgtc gaaggtccgg tatacatatc
    19021 caaagggtgc gacatcgggc cgaactgcta cctccggcct ttcacctgcc ttggcgaagc
    19081 ggtacgcatc ggaagctcgg tggaggtcaa gagctccata gtcatgcgga ggacgcacat
    19141 cccgcatcac aattacgtgg gtgacagcat aatcggcgaa aggtgcaact tcggcgccgg
    19201 caccaaggta gccaacctgc gcttcgacga tcggaccgtt cgggtgacca ccaaggggca
    19261 gatgctcagc accggccggc gcaagctagg ggtgatcatg ggcgatgacg ttaagaccgg
    19321 catcaacgcc atgatcgagc cgggaacggt gatctgggaa ggcaccgtgg tcggcatggg
    19381 cgcccgggcc cgcgggaaca tcgggccgca cagcaaggtc ttctaaagct ccacgaccgg
    19441 aagctgcatg cgccttccct gaccgtcgta agcgcgccag ctgccctcgt cgtaaggcag
    19501 gcaggttatg atgtgcacgt acccatagcg gcggaacagt tccaggtcct ccctggacgg
    19561 ccgattgctg taaccgggat gtgagtgcac cgtgccgacc acggaaaaat cgatgggcat
    19621 catgtgcatc atcaaggtgg ccgaatcctc tccctgaagg gtgcctggca atagcaacag
    19681 ttcctggatg atgccgtcct cggcccgcag catggccacg aactcgttgg gcaacgaatc
    19741 gcgcgccgcc tcgtttatca tctccaagag ggcgcggtcg atgccccgga ccttcagcat
    19801 aggttcccca tcagcttctc cctggtgcgg gcgtagaaac ctttaccgaa gctgacgaag
    19861 cgcgcccggt ccggggaggc cttgaactcc accgtctcgt tgccggccat gagcagctcc
    19921 tgctgaccgt ccacgacgac gacgcactcc ttgggacgga ccacttgcac ggtgatgcgg
    19981 ctgctggccg ggaccaccac cggccgggtg gagaacttga agggggccat gggagcaatc
    20041 accagtgctt ccacccgggg atcgatcagc ggggcgccca ggctcatggc gtaacaagtg
    20101 gaaccggtgg gggtggccac cactatgccg tccgcccgga cgttcatggc catctccccg
    20161 tccacgaaca cctggaagtg acggatcttg gccacgtggg cggtgtgcag caccgcctcg
    20221 ttcatggcat ccagcatgcg cttcccgccc acggtggtct gcagcttgat gcgctcctcc
    20281 agttcgtagt tgccgcgcag gacgttgtct atgccttcct ccagctcctc ctccgaggcc
    20341 acggtgagga atcccaggtc gccggcgttg atgcccagta tgggcgcctt attgtgctgc
    20401 agcgccctga ggatggtgcc atcccctccc acggtcacca tcatgtccac gtccatctcg
    20461 tccaggagca gccccttggt cttgaaccgc tcggccatct ccttctccag cagcacctcg
    20521 tgccccttga gcagttccaa ggtcctcttg gccatgcgcg gggcgtcggg tatgttcatg
    20581 ttcacgctca tcccgaactt cataatagcc acctcaccat cgccgcgtcg cccgcggcca
    20641 ggcagttggc ccggacctcc aggtccaggg ccatatctag gacgttgccg tcaagatcgt
    20701 aaagctcccc gcccgcctcc cggaggataa gggcgctggc ggcgatatcg accaccctca
    20761 acgccctctg gtacacctcc gagttcagat agaaaccgtc ggccagccca gccgccacca
    20821 ggcacatctc caatgacgaa cagcccatgg aacgggtgcg ccgggccttg cgcagcaccc
    20881 cgttggcgga ggccg
//
LOCUS       DAOPZI010000027        19200 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_2985_length_19200_cov_9.644868, whole genome shotgun sequence.
ACCESSION   DAOPZI010000027 DAOPZI010000000
VERSION     DAOPZI010000027.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 19200)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 19200)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19200
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_2985_length_19200_cov_9.644868"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(18..1343)
                     /gene="cca"
                     /locus_tag="PKM11_06160"
     CDS             complement(18..1343)
                     /gene="cca"
                     /locus_tag="PKM11_06160"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: protein motif:HMM:TIGR03671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HNX48123.1"
                     /translation="MSLEDAVLRKIRPKAGTIRRLDEAVEQLRCLTDGSISRSGMDLQ
                     TMLVGSVAKGTYVGEPDIDLFVLFPESVERKDLEKIGLRIGKEVLGGETRYAEHPYTH
                     GKIGGFEVDLVPCYALPDASKIRSAVDRTPFHTRFVLSSLDAAKREQVLLLKQFMKGV
                     GVYGAEARVQGFSGYLTELLIIKFGDLLSVLKAASGWRPGIIMDVNTIKKAGGGAPLT
                     FWDPVDAKRNVSSALSLDQFCLFVHASREYLRGPSERFFFPRKRPLLDIDTIEATFRN
                     RGTSPLSVVLERPDLVDDNLYPQVQRSILGLRKLLEMNDFQVLDMKYSVGKDIRMVFE
                     MVSTDLPPSRLHQGPPACTDNADDFISKWRASGIGQPFILDGKWMVYARREHRDPVTL
                     IRAKGKEAALGNDLRELKGQKCFSGQDAYKKENRRVFTLLLDKREGWRV"
     gene            complement(1497..2291)
                     /locus_tag="PKM11_06165"
     CDS             complement(1497..2291)
                     /locus_tag="PKM11_06165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX48124.1"
                     /translation="MTKLVFLGTGGGRFSTIYQIRATGGLYLMDGVNMHIDPGPSAAY
                     QMHRYQLDPAKTDAVLVSHCHPDHYTDAEVMIEGMSRGGLKKRGTLLASRSVLEGHQL
                     HGPAISNYHRSLLDRIEMALPGGSTEVDGAKIKFTSTRHSDPTGVGFSIETRNGLVSY
                     VSDTELDDKVAREQEGSRLLILPLTRPWGARIPNHLCTEDALEFVKMVKPEMTILTHF
                     GAKLIHAGAERQASMIEKGTGVRTIAADDLMSVQLGKVIRIHRSGS"
     gene            2396..3694
                     /locus_tag="PKM11_06170"
     CDS             2396..3694
                     /locus_tag="PKM11_06170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HNX48125.1"
                     /translation="MARSILIKNGTIITQDQSRRVFVGDILVKNGVIAEMGKVRGGAD
                     EEIDARGAPVLPGLINTHCHVAMSVMKGMADDLPFGDFLNRVFAIDSDRQDEDLLAGS
                     RLGCLEMLTGGTTTFVDLYYSQDVIAQAVKEAGMRGVLCWAVLDQQFTTQNGVPLDNC
                     KSFHSRFAGDKNIVPGIGLQGVYVCSEETFMGSREFSDRTGALMTFHLSETRGEVYEH
                     KNKTGKRPGDWLSSIGFLNDKCLAAHSAWLTINEVRALAKAGASISSCPVSNMKLATG
                     GVTPIPEMLREGVNVTIGTDGSTTNNSMDMFGEMKTLALLQKSSRWDPTVVKAQEALD
                     FATVNAAMALGLQKQIGSIEVGKQADIVIMDSRSPTLRPLTLENAVSNVVYSASRGDV
                     RTVLCFGDIMVRDRVPQNLDMDSVIEDGQKAMATISAKRK"
     gene            complement(3701..3812)
                     /locus_tag="PKM11_06175"
     tRNA            complement(join(3701..3739,3774..3812))
                     /locus_tag="PKM11_06175"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3775..3777),aa:Tyr,seq:gta)
     gene            4001..4240
                     /locus_tag="PKM11_06180"
     CDS             4001..4240
                     /locus_tag="PKM11_06180"
                     /inference="COORDINATES: protein motif:HMM:NF013561.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HNX48126.1"
                     /translation="MEEGDLEKVTLRLPARHIRALDFLVQVDDFPSRSEAIRAAIRDF
                     IYARVDLVADKMKKMEEAERVLAEMEAYEERYMRK"
     gene            complement(4332..5090)
                     /locus_tag="PKM11_06185"
     CDS             complement(4332..5090)
                     /locus_tag="PKM11_06185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteasome assembly chaperone family protein"
                     /protein_id="HNX48127.1"
                     /translation="MDSVITIMHERPELRSPILIEGLPGVGNVGKLAAEHLVEQVKAI
                     KFADIYSKHFPPQVLLDEDGVIRLVNNELHYYRGEGERPDIVIMTGDYQGMTPDGQYE
                     LSYHAIQLCKDLGISRIYTLGGYGVGKIVDKPRVLGAVTDISLCEEMTEHGVIFSKGE
                     PGSGIVGASGLMLGLGKIEGIPAVCLMGETSGYFVDPKGAEAVLRVLMSLMHIELDLT
                     ALTDKAEQIDLIANKLKEAETPDVPKREDLGYIG"
     gene            complement(5096..5257)
                     /locus_tag="PKM11_06190"
     CDS             complement(5096..5257)
                     /locus_tag="PKM11_06190"
                     /inference="COORDINATES: protein motif:HMM:NF009623.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-protein complex protein Nop10"
                     /protein_id="HNX48128.1"
                     /translation="MKTTLRICERCREYTLKDTCPRCGSQTSTPIPPRFSPDDRYGEY
                     RRRARQENK"
     gene            complement(5318..6100)
                     /locus_tag="PKM11_06195"
     CDS             complement(5318..6100)
                     /locus_tag="PKM11_06195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 subunit
                     alpha"
                     /protein_id="HNX48129.1"
                     /translation="MSRVGEFPEEGELVVCTVQSVKNFGAFVTLDEYGDKEGFIHVRD
                     VATGWVKYIRDYVREGQKVVTKVLGVDSTKGHIDLSLKSVNEHQRREKVQQWKNETKA
                     EKLLEIVATRLEKTPDECWEEFGYQLVDAFGTLYGAFESCAIDEAVLEEAEISGDWKD
                     AFVEVAKENVTPPFVQIAGILELRSPAPDGVDRIKAALKKGLEASTEEMHIQYIGAPR
                     YRLVMSAPDYKTAEEALKEVTNLVVAEIKDNGGDGTFHRDAK"
     gene            complement(6100..6273)
                     /locus_tag="PKM11_06200"
     CDS             complement(6100..6273)
                     /locus_tag="PKM11_06200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S27e"
                     /protein_id="HNX48130.1"
                     /translation="MATTGKFIKVKCQDCGNEQITYKKPAMNVACAVCGSTLVKSRGG
                     EGEVRGELLEVVD"
     gene            complement(6279..6551)
                     /locus_tag="PKM11_06205"
     CDS             complement(6279..6551)
                     /locus_tag="PKM11_06205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L44e"
                     /protein_id="HNX48131.1"
                     /translation="MPRSIKTYCPSCKTHTDHEVERVKKKKASEMKWGQRRFRRATAG
                     YGGFPRPKPEGREKPTKRIALRYRCKKCKKAHQKTCFRAKKFELTE"
     gene            7049..7420
                     /locus_tag="PKM11_06210"
     CDS             7049..7420
                     /locus_tag="PKM11_06210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HNX48132.1"
                     /translation="MADKGFNKKDESLVELLVNTGMPKNVAKTLAFLRKKEETTSVEI
                     EIMTALRQPEVSIAMQELRRRKWVIKRDIKKEGKGRPVHSYKLAIPFDKIIETLDKEE
                     RKRMESIEKNIDQLKALSLNP"
     gene            complement(7421..8095)
                     /gene="rpiA"
                     /locus_tag="PKM11_06215"
     CDS             complement(7421..8095)
                     /gene="rpiA"
                     /locus_tag="PKM11_06215"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HNX48133.1"
                     /translation="MSEKKRLAAEKAVELVQDGMKVGLGTGSTAYFAIEAIGRLVKDG
                     YKILAVPTSLASEKQARELGIPLATLEEAGTLDITIDGADEVDGNLDLIKGMGGALLR
                     EKIVAYSTRVQVIVVDDSKIVSKLGTKFPLPVEVVPFAHARTKTYLEELGCRAELRGG
                     GTPFITDNGNHIYHLHFERGIKDPYELQNKLKEIPGVVETGLFLNMAKKVIVASDPGI
                     WVMERV"
     gene            complement(8097..8798)
                     /locus_tag="PKM11_06220"
     CDS             complement(8097..8798)
                     /locus_tag="PKM11_06220"
                     /inference="COORDINATES: protein motif:HMM:NF014670.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="creatininase family protein"
                     /protein_id="HNX48134.1"
                     /translation="MDEMSSASFAEEVKRDPIVFLPMGAMEAHGPHLPLGTDTFQPEF
                     VVKAVSDNVNGIVAPTINYGQHSSTRNFPGTIDISFDTIRALVMDILDAFQRNGIKKV
                     VIVSGHLGSVHRSAIKLACERAARQGLKVMFLSDYELAYLKKPDVCEGQPDGHGGIIE
                     TSRIIDIRPDLVKEERTAGEFVDTHFMVRADAECCLPQGFGGDARRANKEKGRFVNQF
                     VIEALTDLVRQNFEG"
     gene            complement(8801..8965)
                     /locus_tag="PKM11_06225"
     CDS             complement(8801..8965)
                     /locus_tag="PKM11_06225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48135.1"
                     /translation="MALHCPRCNKNIDKAKVDEIDARLMSTYNNDALRRGLCPVCMTP
                     LIDTEKKVSH"
     gene            9050..9718
                     /locus_tag="PKM11_06230"
     CDS             9050..9718
                     /locus_tag="PKM11_06230"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: protein motif:HMM:NF014015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HNX48136.1"
                     /translation="MRLACLFSGGKDSTYAAHLMEQAGHEVVCLVTVVPEDPHSWVFH
                     TLNLEHLPEMAKAMGKDLIAVPSSGEEGADLAALETALSGLDVEGVITGAIASDYQWD
                     RINGVCHKLGLKVFSPLWRIDQLTILNDMLQAGMRVMMVGVYSDGLGPGWLGRMLDRG
                     TVDQLSSLAKARGMNVSGEGGEYETLVLDSPMHSYPLVPQDLQVDFERDSGQLRIGRL
                     IASR"
     gene            complement(9702..10190)
                     /locus_tag="PKM11_06235"
     CDS             complement(9702..10190)
                     /locus_tag="PKM11_06235"
                     /inference="COORDINATES: protein motif:HMM:NF020123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016209 - antioxidant activity [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HNX48137.1"
                     /translation="MDLDRMPKVGQKAPDFLLPDDAGNMLRLSELSRKGVVLLLFYPA
                     DFGMICSIQMGELRDAHQEFVSAGVIVLPLGTNSVRSHAAWKESMRLPFPLLADEDGT
                     VTREWHMSCDDDAWLKNRSCRGAFIIDREMMVRYRWIPPNPHVGPDVPSLLQEASAIA
                     KR"
     gene            complement(10193..10696)
                     /locus_tag="PKM11_06240"
     CDS             complement(10193..10696)
                     /locus_tag="PKM11_06240"
                     /inference="COORDINATES: protein motif:HMM:NF020123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin family protein"
                     /protein_id="HNX48138.1"
                     /translation="MTEDLVGKPFHDWTMRNELDQDVKLSDRWANRTVLLLVFSSAFG
                     VVCNLEMLTFTAMKKAFDEANCEIFGVSNDSQRSLGAYSENLNIGFHLLSDEGARMSR
                     SLKAMEADDGPWPGFPKRSEFMIDRKGIIRYAHIPPDSNWEPDYDAILLEARKIAEEY
                     RQEDQGR"
     gene            complement(10804..10878)
                     /locus_tag="PKM11_06245"
     tRNA            complement(10804..10878)
                     /locus_tag="PKM11_06245"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10840..10842),aa:Pro,seq:tgg)
     gene            10961..12097
                     /locus_tag="PKM11_06250"
     CDS             10961..12097
                     /locus_tag="PKM11_06250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48139.1"
                     /translation="MKKAWVAMVIVGAVVAMLLLYYLLGGFVQDPSGFQEDDLQAPFV
                     SDVVRNDEYPGPLSGSNYPMHVQPSVSYGLLVYADFGGVLELFMENEGSNEVYVHHYY
                     VFWEGGNETFQVNCSRLISSGEVKGLGELYFAGPGEPGPATLEVWAEVWTSSPNGMLW
                     DDQGEMLISTIDLNVVEEGSLREWKVERNPVQYYNKVNGLIDLEVVSSMASDVRSAVP
                     GNYSLLQVIEAYELISQSIDYAEDEDNHWQSPAETIALGSGDCEDHSLLMASLITVLG
                     GNCRVNLIAGHAFPSVYVGNDSVIGEVIETIQAYYGNPVPVHYTVDDLGYWMIVDTNG
                     LPYVGGYPAASSPAGGAGGVNWSSDDGDWIKLIDVTGETVDTLF"
     gene            complement(12094..13059)
                     /locus_tag="PKM11_06255"
     CDS             complement(12094..13059)
                     /locus_tag="PKM11_06255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HNX48140.1"
                     /translation="MKIRGSNIVVTGCAGFIGSHLTDALLAMGNHVVGVDNFSAGRRE
                     FMENAEGYTDFRFVQADLLKDDLRPIFKGADAVMHLAANPDVRSGAKDTLSLYQQNIE
                     VTYRVLEAMKDTGVKDILFPSTSTVYGEPTVIPTPENYGPLVPISVYGATKLACEALI
                     SSYAHSFDMNGVIFRFANVVGTRSTHNVLHDFTNKLKADPGRLEILGSEPGTTKSYVH
                     VEDCVRGMIIGAEYARNKIEMFNLGSNDRMSVKDIADTVTEVMGLRGVRYEWTGGVQG
                     GRGWIGDVKNMLLSSDKLRSYSWEPTMNSSQAIKRAVREIVGRGA"
     gene            complement(13056..13622)
                     /locus_tag="PKM11_06260"
     CDS             complement(13056..13622)
                     /locus_tag="PKM11_06260"
                     /inference="COORDINATES: protein motif:HMM:NF013854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-canonical purine NTP pyrophosphatase"
                     /protein_id="HNX48141.1"
                     /translation="MKLGLVTSNKHKLEEYRHGLERLGVNIELLQADCEEIQTDTLQN
                     VVRSCIAQLKSEGYRNFMLDDSGLFVPSLNGFPGVYSAYVMDTIGCQGMLRLIDGLDR
                     KARFECCIGVCSDELGEFSVTGVSPGRIIYEERGSGGFGYDPIFVPDGGELTFAQMDL
                     ASKNQLSHRGKAMVLLAAEIKRRMGKLK"
     gene            complement(13619..14233)
                     /locus_tag="PKM11_06265"
     CDS             complement(13619..14233)
                     /locus_tag="PKM11_06265"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: protein motif:HMM:NF011462.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KEOPS complex kinase/ATPase Bud32"
                     /protein_id="HNX48142.1"
                     /translation="MKVIRRGAEAEIRRDEFMGRQVLVKSRVPKSYRHPALDQSLRSH
                     RTRVEARLLQEARSCGVPTPIVYDIDMERAEIWMQEIVGPRAKDALLNASAEEVRAIS
                     QEIGRMVARLHSHGMTHGDLTTSNMILQDGRVFFIDLSLGSKAASLEEMGVDLHLLKE
                     AFQSAHSDMMYAYEIIVETYVREHAGGRDVLAKVKDIEERGRYA"
     gene            complement(14246..>15742)
                     /locus_tag="PKM11_06270"
     CDS             complement(14246..>15742)
                     /locus_tag="PKM11_06270"
                     /inference="COORDINATES: protein motif:HMM:NF024703.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HNX48143.1"
                     /translation="PRQSQHRAIIETVKMMPRNIATVDLLSRDSMCPLGPRPPCLDGR
                     RCHLQADGKITKCAKEILARPMHAQEAVALCLRRGACPYISAKMASSGAELVVGDVSR
                     VFGNLPDVIRFRSSSRKQHLVTDEAHNLPVRIMDAFSRDLVLDPAAEDPLRAVWKEML
                     SRGHRLIPLGELRSLLDRFGLPEPEELEDSDPMVGDWMRLGDSAVRVAYPIENRISLR
                     FLEPDLLVRNVVQECQGAIFMSGTLHPPEVFAARMGLAEAMCRSYPSPFDPARRLALA
                     IPDVGTRFRDRCHQTTMDMALRIGELAEQVPGNVMVFLPSYVYMSAVHRTLRRLGQRK
                     MLLSESPLMSKADRDGLADLLGGEREVLMLCNIRGSFSEGVDLPAGCLSAVMVAGLPL
                     TPPSLERKEMLFRASSKIGDGHDLETYEALSRVLQACGRAIRREEDRAAVVLLDPRYL
                     ERKVQKMIPPDLRFTEGDPVELLSEFFGTSSESIWKLQGEGERIITGH"
     assembly_gap    15743..15842
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <15843..16569
                     /locus_tag="PKM11_06275"
     CDS             <15843..16569
                     /locus_tag="PKM11_06275"
                     /inference="COORDINATES: protein motif:HMM:TIGR00266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HNX48144.1"
                     /translation="RISGNINKSVTVLGEIVKYTITGDNLQFVNVEFMPGEMIYSEAG
                     SMIYMSGNVRLETKAAGGLMGGLKRAVSGESFFVTNFYAEGGPGLVGFGGSVPGKCMA
                     IDLRGGRQWLLQKTAFLAAEAQVNLDIAFQRKFGAALFGGEGLVLQKVQGEGTVFISG
                     SGDFIEYNLLPGQVMKVSTANVAAWEASVSYDIQSLGIKTALFGGEGLFVTTMTGPGR
                     IVLQSMTMSKLANSIVPFLPNRG"
     gene            16601..16840
                     /locus_tag="PKM11_06280"
     CDS             16601..16840
                     /locus_tag="PKM11_06280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48145.1"
                     /translation="MALLVIAMIGVALLAVWYLDWVLAAIIVLVAAAFLVLVLAAVLG
                     GLAIIPYYFAKRGRDTQPGSYTLEQVKDIKDQERK"
     gene            16837..17547
                     /gene="radB"
                     /locus_tag="PKM11_06285"
     CDS             16837..17547
                     /gene="radB"
                     /locus_tag="PKM11_06285"
                     /inference="COORDINATES: protein motif:HMM:NF020014.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair and recombination protein RadB"
                     /protein_id="HNX48146.1"
                     /translation="MNVEELRLVPFQCPPLDEMLSGGIESGCLTLIYGEAGTGKTNLC
                     LTLAKNLAQEGRKTIYVDSEGISLLRLRDIAGDDQERVLKEVLISEVHSLDDQDRMIG
                     KAIKLAEGNPDVGLIVVDSMTMFYRLASKDDERAERRVLAGQSAKLLTAARKLNLPVV
                     ATSQVYTDVETGMFEALGGNVLHHNAKTIIRIEKLGPGKRRAVIMKHRNLAEGRFGVF
                     YLTDKGIEAEPQSSRPTA"
     gene            complement(17523..18509)
                     /locus_tag="PKM11_06290"
     CDS             complement(17523..18509)
                     /locus_tag="PKM11_06290"
                     /inference="COORDINATES: protein motif:HMM:NF012568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HNX48147.1"
                     /translation="MDHQQRTNDIIKEVDRSLMRYVERGKHEKLIKAMRHYPEAGGKR
                     MRPVMAILAAEAVGKRGKEALPFGCALEIIHNFTLVHDDVIDKDPVRRGRPAVHIAFD
                     EPTAIIAGDALFAIAFDVLATTDIDGERLRRLLHTVSDTVFLVAEGQQIDVDNEDRPT
                     VSREEYLDMVEKKTAVLFACAAEGGAIIGHGSEKQITDMKEYARLLGIGFQIWDDVLG
                     IKGDAKKVGKPVGSDIRNGKRTLIVVDALERLEKDKRRHVLTDALGNAKASDEQVKAA
                     VQLLDDIGSIEHARQFALDYAKRAKDLLSCLKDSEEKEMLREMVDYAVGREL"
     gene            complement(18515..>19200)
                     /locus_tag="PKM11_06295"
     CDS             complement(18515..>19200)
                     /locus_tag="PKM11_06295"
                     /inference="COORDINATES: protein motif:HMM:NF013253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HNX48148.1"
                     /translation="QLVKQKGKSAFTVDDVLRAQEVVGADIMAVHLNFLQEVVQPNGD
                     VNAKGCLDGIRAIAREGPTMVKETGAGISRETALLLKGTGIRGMDVSGVGGTSFAAVE
                     MHRAIAQENLLASALGRTFFDWGIPAPAAVLEADVGLEIIASGGIDDGLRMAKGLAIG
                     ANAAGCARAVLAEAMESSQAVLDKINIMKAELKAAMFLTGCGSVDELRQRRVIVSGRT
                     ADWLTASED"
BASE COUNT         3768 a         5798 c         5440 g         4094 t
ORIGIN      
        1 tcggtcaacg ttaaggccta gacccgccaa ccttcccttt tatccaacag gagggtgaac
       61 accctccgat tctctttttt ataggcgtcc tggccagaga agcacttctg tcctttcaac
      121 tctcgaaggt cgttccccag ggccgcctcc ttacccttgg ctcggataag ggtgaccggg
      181 tcgcggtgct ctcttctggc gtagaccatc cacttgccgt cgagaatgaa aggctggcct
      241 atcccggacg ccctccactt gctgatgaaa tcgtcagcgt tatccgtgca tgccggggga
      301 ccctggtgca atcgtgatgg tggtaggtcc gtggacacca tttcgaagac cattcgaata
      361 tcctttccga cggaatattt catgtctagc acttggaagt cgttcatctc caacagcttc
      421 ctgaggccca gtatgctcct ctggacctgc gggtagaggt tgtcgtccac caggtccgga
      481 cgttccagga ccaccgagag cggggaggtc ccccggttcc ggaaggtggc ctcgatggta
      541 tcgatgtcca gcaaaggcct ctttcggggg aagaagaatc gttcgctagg tccccgcaga
      601 tactcgcggc tggcgtgcac gaagaggcag aactggtcta gagacagggc ggaggaaacg
      661 ttccgcttgg cgtcgaccgg gtcccagaac gtcagcgggg cgccgccccc tgccttcttg
      721 atggtgttga cgtccatgat gatgccaggt cgccatccgg aggcggcctt gagcacgctg
      781 agcaggtcac cgaactttat gatcaacagc tccgtaaggt aaccagagaa gccttgcact
      841 ctggcctccg cgccgtagac tcccactccc ttcatgaact gcttcagaag aaggacctgc
      901 tctcgcttgg ccgcgtccaa acttgatagc acgaacctgg tgtggaaagg cgtacggtcc
      961 accgccgatc tgatcttcga agcgtccggt aacgcgtagc agggtacaag atcgacctcg
     1021 aaccctccga tcttgccgtg ggtgtatggg tgctcagcgt atctcgtttc accgcccagc
     1081 acctcctttc ctatgcgcag gcctatcttt tccaggtcct tgcgttccac cgattccggg
     1141 aacagtacga agaggtctat gtccggctcg cccacgtaag tgcctttggc caccgagccc
     1201 accagcatgg tctgaaggtc catcccgcta cgggatatcg atccatcggt caggcaccgg
     1261 agctgctcaa ccgcctcatc cagtctcctg atcgttccgg ccttcggcct tatcttgcga
     1321 aggaccgcat cctccaagga catggtccgg acattaggta tgtgcattat catcttttag
     1381 gaaaaaatcg cagccggccg gggtggtggg ggtttctgaa ctaataggag gaagatcccc
     1441 ggcctatgtg cgctgcacta tatactatgt aagcgctact atataataat aactgtttaa
     1501 gacccagagc ggtggattcg aattacctta cccagctgta cgctcatcag gtcgtccgcg
     1561 gcgatggtgc gaactccggt tcccttttcg atcatgctcg cctgcctctc cgccccagcg
     1621 tggatgagct tggcgccgaa gtgggtcagg atggtcattt ccggtttcac catcttaacg
     1681 aactccaggg cgtcctcggt acacaggtgg ttcggtatcc tggcacccca aggtctggtc
     1741 agtggtaaga tgagcagtct gctcccctcc tgctccctgg cgaccttgtc atccagctcg
     1801 gtatcgctga cataggacac cagtccgttt cgcgtctcta tggagaatcc gaccccggtc
     1861 gggtcgctgt gcctggtgct ggtgaatttg atcttcgcgc catcgacctc ggtgctgccg
     1921 cccggcaagg ccatctctat gcggtccagg agagaacggt gatagttgga tattgccgga
     1981 ccatgcagtt gatggccttc caggacggaa cgagaggcga gcagcgtacc tcttttcttc
     2041 aggccgccgc gggacatgcc ctcgatcatg acctccgcgt ccgtgtagtg atcgggatgg
     2101 caatgggaga ccagcaccgc atcggtcttg gccgggtcca attgatagcg gtgcatctgg
     2161 tacgccgcgg acggaccggg atcgatgtgc atgttcaccc cgtccatcag ataaagtcca
     2221 ccagtggccc ttatctggta tatggtggag aaacgcccac cccccgttcc caggaacacc
     2281 aatttggtca tcacagctcc gtatcttaac gatgtgagga cccatgcggg aactgtaaaa
     2341 ttaaacttgc gaccccggca tacaattatt atcgccggaa agccttcctg ggccgatggc
     2401 tagaagcatc ctcatcaaga acggaacgat catcacccag gaccagtccc gcagggtgtt
     2461 cgttggagac atcctagtta agaatggcgt catcgccgag atggggaagg tccgcggcgg
     2521 cgccgacgag gagatcgacg cccggggcgc accggtcctt ccggggctga tcaacaccca
     2581 ttgtcacgtc gcgatgtccg tcatgaaggg aatggccgac gaccttccgt tcggtgattt
     2641 cctcaaccgg gtgttcgcca tcgactcgga ccgccaggac gaggatctgc tggccggctc
     2701 ccgtctggga tgcctggaga tgctcacggg cggtacgacc accttcgtgg acctctacta
     2761 ttcccaggac gtcatcgccc aggccgtgaa ggaggcgggg atgcgcggag tgctatgctg
     2821 ggctgtccta gatcagcagt tcaccactca gaacggtgtt cctctggaca attgcaaatc
     2881 cttccattcg cgattcgccg gcgacaagaa catagtgccg ggaatagggc tgcagggcgt
     2941 ttacgtgtgc tcagaggaga ccttcatggg ttcccgggag ttctccgacc gcaccggggc
     3001 gctcatgacc ttccatctgt ccgaaacaag gggagaggtc tacgagcaca agaacaagac
     3061 cgggaagcga ccgggcgact ggctttcgtc catcggcttc ttgaacgata aatgcctggc
     3121 cgctcattcc gcctggctca ccatcaacga ggttcgagcg ctggccaagg ccggtgcctc
     3181 catatcctca tgtccggtct ctaacatgaa gctggccacc ggcggtgtga cgccgatacc
     3241 ggagatgctc agggaaggcg tcaacgtgac catcggcacg gacggttcga ccaccaacaa
     3301 ttccatggac atgttcggag agatgaagac gctggccttg ttgcaaaagt ccagccgctg
     3361 ggaccccacc gtggtcaagg cccaggaagc gctggacttc gcgacggtga acgccgctat
     3421 ggcgttagga ttgcagaagc agatcggttc catcgaggtc ggcaagcagg cggacatcgt
     3481 gatcatggac tcccgttcac cgacgctccg gccgctcacc ctggagaacg cagtatccaa
     3541 cgtggtctac tcggccagcc gcggtgatgt gagaacggtg ctgtgctttg gcgatatcat
     3601 ggtcagggac cgcgttccac agaacttgga catggattcg gtcatcgagg acgggcagaa
     3661 ggccatggcc accatctcgg ccaaacggaa gtaaaaggaa tggtcccgac tcccggattt
     3721 gaaccgggca cctgctgata tcggcggctg aggaccggca agccgggatc ccactacagt
     3781 cagccgctct agccagactg agctaagtcg ggtgtaagcc accataatac agatagcgta
     3841 tttatcaatt atcgtgtgcc ccaagcgtac aaatcgtcca atatttcggt ctgggtaggg
     3901 cgaggtcgtt caggcacctt aaaaaacttt tatatatgaa ccaagtcata gtgttgtcgg
     3961 acaatagagg tctaacagac ctacgttgtc aggaagcacg atggaagaag gcgacctgga
     4021 gaaggtcaca ttgcgattgc cggctaggca catccgggct ctggatttcc tagttcaggt
     4081 agacgacttt ccctccagat cagaagccat aagagctgcc atcagggact tcatatacgc
     4141 tagggtcgac ctggtcgccg acaagatgaa aaagatggaa gaggccgaga gggtcctagc
     4201 ggagatggaa gcctacgaag agcggtatat gaggaaatag cctgccagga agggatggga
     4261 tgcacctagt caggcccaag gttccccccc ggaaccttcc ctcttttttc tttttttaaa
     4321 attaaaatgg tttagccgat gtagcccagg tcctcgcgct tggggacgtc cggggtctcg
     4381 gcttctttca atttgttggc gatgaggtcg atctgttcgg ccttgtcggt cagggcggtg
     4441 aggtccagct cgatgtgcat aagggacatg agcaccctca gcaccgcctc ggctcccttg
     4501 gggtcgacga agtaaccgga cgtctcaccc atgaggcaga ccgccgggat cccctctatc
     4561 ttgcccagcc cgagcatcag cccggaagcg ccgacgatgc cgcttcccgg ttcccccttg
     4621 gagaatatga cgccatgctc ggtcatctcc tcgcacagag agatgtccgt gaccgccccc
     4681 agcacccggg gcttgtcaac gatcttgccg accccgtagc cgcccaaggt gtagatgcga
     4741 cttatgccca ggtccttgca gagctggatg gcgtggtatg atagttcgta ctgaccgtcg
     4801 ggcgtcatgc cctggtagtc cccggtcatg atcacgatgt ccggccgttc gccctcgcca
     4861 cggtaatagt gcagttcgtt gttgaccagg cggatcacgc catcttcgtc cagtaggacc
     4921 tgcggcggga aatgcttcga atagatatcg gcgaacttga tggccttgac ctgttccacc
     4981 aggtgctccg ccgccagctt accgacgttg ccgacccctg gcagtccctc gatgagaatt
     5041 ggggagcgca gctcgggcct ctcatgcatg atggttatga cgctatccat gtgaatcact
     5101 tgttctcctg gcgcgccctc cggcgatatt ctccgtatcg atcgtccgga gagaacctcg
     5161 gcggtatggg cgtggaggtc tgggaaccgc atctggggca ggtatccttg agagtatact
     5221 cccggcacct ttcacatatc ctcagggtgg tcttcatagt cctatcgcct gcggaccagt
     5281 ataagcctag acctcgataa atcactttgc cgtactatca cttggcgtca cggtggaacg
     5341 ttccatcccc accgttgtcc ttgatctcgg caactaccag attggtaact tccttcaagg
     5401 cctcttccgc ggtcttgtaa tcaggggcgc tcatcaccaa tcggtaacgg ggagcgccga
     5461 tgtactggat atgcatctcc tcggtggatg cttccagacc tttcttgagg gcggccttga
     5521 tgcggtccac tccgtccgga gcgggggagc ggagctccaa tatcccggct atctgaacga
     5581 agggtggggt gacgttctcc ttggccacct cgacgaacgc atccttccag tctccggaga
     5641 tctccgcctc ttccaggacg gcctcgtcga tggcgcagct ctcgaacgct ccatatagag
     5701 tgccgaatgc gtccaccaac tgatatccga actcttccca gcattcatcg ggggtctttt
     5761 ccaggcgggt ggccacgatc tccagaagct tttcggcctt ggtctcgttc ttccactgct
     5821 ggaccttctc ccggcgctga tgctcgttaa ctgattttaa agaaagatcg atatgtccct
     5881 tggtcgagtc cacacccaga acctttgtga cgaccttctg gccctccctc acgtagtcac
     5941 ggatgtactt tacccatcca gtggccacat cgcgtacgtg gatgaagcct tccttgtcgc
     6001 catactcatc gagcgttacg aacgctccga agttcttgac gctctgcaca gtgcagacca
     6061 cgagctcccc ttcctcgggg aactcgccga cccttgacat tagtcgacca cctcaagcag
     6121 ctctcccctg acctcgccct cgcctccgcg ggacttgacc aaggtagagc cgcacaccgc
     6181 gcaggccacg ttcatggccg gcttcttgta ggtgatctgc tcgtttccgc aatcctgaca
     6241 ttttactttt atgaacttac cggtggtggc cattcaaatc actccgtcag ctcgaacttc
     6301 ttggcccgga agcatgtctt ctggtgggcc ttcttgcact tcttgcagcg gtatctgaga
     6361 gcgatcctct tggtaggctt ctcgcgtccc tcaggctttg gcctggggaa accaccgtaa
     6421 ccggcggtag cccggcggaa ccttctctga ccccacttca tctcgctggc cttcttcttc
     6481 ttaactctct cgacctcgtg atcggtgtga gtcttgcagg atggacagta agtcttgata
     6541 gacctaggca tcttcataac attcatccca ttggagcaaa aaagccctaa tactcaatct
     6601 ctatttaaac ccttagcatg ggaaaaaacc ccaccccagc atactgggtt agctaactca
     6661 accgttcgca tatcggttag catgccagtt cgtcgattgc tataacagat catcggtgaa
     6721 caattaattt tcaagttaaa tgatcaaatc aatcaacatt cgtatccata atttgatcac
     6781 aggacagtta tgatcgagag ccccgaatta actgtgctac accttatcaa tcgtaaaata
     6841 ataatcgaaa gcttataata gggctgcatt tctcggggga ttcccgaaca taatatttgc
     6901 tgatggccat taaagtttaa cagaccttaa aaagtgtgag ccagtggtat gttcagcata
     6961 ataaaatatt atgtgaatag aaaggcatat atatcaatca aataataatt gatacgtatc
     7021 tataaattag aaaaaagggt gatgcataat ggccgacaaa ggcttcaaca agaaggacga
     7081 atctctcgtc gaactgctgg taaacaccgg aatgcccaag aacgtagcga agaccttggc
     7141 tttcctacgc aagaaagagg aaacgacatc tgtcgaaatt gagatcatga ccgcactacg
     7201 tcaacccgaa gtttccatcg ccatgcagga gcttcgccgc cgcaagtggg tcatcaagag
     7261 ggacatcaag aaggagggca agggccggcc ggtgcactcc tacaaactgg caattccctt
     7321 cgacaagatc atagagacct tggacaagga agagcgtaag cggatggagt cgatcgagaa
     7381 gaacatcgat cagctcaagg cgctctccct gaacccctga tcaaaccctt tccatcaccc
     7441 atatcccggg gtcggaagcc acgatcacct ttttggccat gttcaggaac aggccggtct
     7501 ccaccactcc cggaatctct tttagcttat tctgaagttc gtaagggtct ttgatccctc
     7561 tctcgaaatg cagatggtag atgtggttgc cattgtcggt gatgaacggt gttccgccgc
     7621 cccgtagctc ggcccggcat cccagctcct ccaggtaggt cttggtccgg gcgtgggcga
     7681 aaggaaccac ctccactggc agggggaact tggtcccaag cttggagacg atcttcgaat
     7741 cgtcgaccac gatgacctga acgcgagtgg agtacgccac gatcttttcc cggagcaggg
     7801 caccgcccat tcccttgatc agatcgaggt ttccgtccac ctcgtccgcc ccgtctatgg
     7861 tgatgtccaa ggtcccggcc tcttccaagg tcgccaaagg aatccccaat tcccgggcct
     7921 gtttctcgct ggccaaggat gtcggtacgg ccaatatctt atagccatcc ttcaccaggc
     7981 gcccgatcgc ctcgatggcg aagtaagcgg tgcttcccgt tcccagtcct accttcatgc
     8041 cgtcctgcac cagctccacg gccttctccg ctgccagcct cttcttttcg ctcatgctaa
     8101 ccctcaaagt tctggcgtac caggtccgtc agcgcctcga tcacgaactg gttgacgaac
     8161 ctgcccttct ccttgttcgc cctcctggca tccccgccga agccctgcgg caggcagcac
     8221 tcggcatccg cgcgcaccat gaaatgagta tccacgaact ccccggcggt tcgttcctct
     8281 ttcacaaggt ccggtcggat gtcgatgatc ctggacgtct ctattatgcc cccgtgaccg
     8341 tcaggctgcc cctcgcagac gtccggtttc ttaagatacg ccagctcata atcgctgagg
     8401 aacatgacct tcagcccctg gcgggccgct ctctcgcagg ccagctttat ggccgagcgg
     8461 tgcacggaac ccaggtgacc ggagactatg accaccttct tgatgccatt gcgctggaag
     8521 gcgtccagga tgtccatgac caaggcacga atcgtatcaa agctgatgtc gatcgttccg
     8581 ggaaagttcc tggtggagga gtgttgaccg tagttgatgg tgggggccac gataccgttc
     8641 acgttgtcgc taacggcctt gaccacgaac tccggctgga aggtgtccgt gcccaggggc
     8701 agatgcggac catgggcttc catggcgccc atgggtagga agactatggg gtccctcttc
     8761 acctcttcgg cgaacgaggc ggagctcatc tcgtccatcc tcaatggctc accttcttct
     8821 ccgtatctat caagggcgtc atgcataccg ggcacaaccc tcgcctaaga gcgtcgttgt
     8881 tataggtgct cattagccgg gcgtcgatct catcgacctt ggccttgtcg atgttcttgt
     8941 tgcagcgcgg acagtgtaaa gccattctcg taccgcagag gttatgttcg gaaatcaatt
     9001 tcaatccttg ccccgcatgg gttaaatctg ccgaggcgat tcacggttca tgcgcttggc
     9061 ctgtctcttc tccggtggaa aggattccac gtacgccgcc catctgatgg aacaggctgg
     9121 gcacgaggtg gtctgtctgg tcaccgtggt tccggaggac ccgcactcct gggtgttcca
     9181 tactttgaac ctggagcatc tgccggagat ggccaaggcc atgggcaagg accttatcgc
     9241 cgtcccctcc agcggcgagg agggggccga cctggcggcc ctggagaccg cgctgtcggg
     9301 tctggacgtg gaaggcgtca tcaccggggc catcgcctcc gattaccaat gggaccggat
     9361 caacggcgtc tgtcacaagc tcgggctcaa ggtgttctcg ccgctgtggc gcatcgacca
     9421 gctcacgatc cttaacgaca tgctgcaggc cgggatgagg gtgatgatgg tcggggtgta
     9481 ctcggacggt ctgggcccgg gatggttggg caggatgctg gaccgcggca cggtcgatca
     9541 gctctcctcg ttggccaagg caaggggcat gaacgtctcc ggggagggag gggagtatga
     9601 gacgctggtg ctggattcgc cgatgcactc ctatccgctc gttccacagg accttcaggt
     9661 cgatttcgaa cgtgattcag ggcagctgcg tatcggccgc ctcatcgctt cgcgatagcc
     9721 gacgcctctt gtagaaggga aggcacatcg ggaccgacgt gcgggttagg cggtatccaa
     9781 cggtagcgga ccatcatctc ccggtcgatt atgaacgccc cccgacagga ccggttctta
     9841 agccaggcgt catcgtcaca ggacatgtgc cattccctgg tgacggttcc gtcctcatct
     9901 gccagcaacg ggaacggtaa gcgcatcgac tccttccagg ccgcgtgcga ccggacgctg
     9961 ttggtgccta gcggcagaac gatcacgccc gcggagacga actcctggtg agcgtcccgc
    10021 agctcaccca tctgtatgct gcatatcatt ccgaaatcgg ccgggtagaa cagcaggaga
    10081 acgacccctt ttcggctcag ctcgctaagg cgcagcatgt tcccggcatc gtccggcagt
    10141 aggaaatcag gcgccttctg accgaccttg ggcatcctat cgaggtccat gactatctcc
    10201 cctggtcctc ttggcgatac tcctcggcga tcttcctcgc ttccagtagt atcgcgtcgt
    10261 agtccggctc ccagttggag tccgggggga tgtgcgcgta gcgaattatc cccttgcggt
    10321 cgatcatgaa ctcggaacgc ttcgggaacc ccggccacgg tccgtcatcc gcctccatgg
    10381 ccttcaggct cctggacatc ctggctccct cgtcgctcag caggtggaag ccgatgttca
    10441 ggttctcgct gtaagcgccc agtgaccgtt ggctgtcgtt gctgacgccg aatatctcac
    10501 agttcgcctc atcgaacgcc ttcttcatgg cggtgaaggt caacatctcc aggttgcaca
    10561 ccaccccgaa ggccgaggag aacaccagca gcagaacggt gcggttggcc cagcggtcgc
    10621 tcagcttgac gtcctggtcc agctcgttcc tcatggtcca gtcgtgaaat ggctttccta
    10681 ccaggtcctc ggtcacagga tatggagggt tggaacggat aataataggt tcgtcgaccc
    10741 gttcaaggcc aggatggcct cgatatagca cagcgcatgc tccgctcgtt aatggagaaa
    10801 aagtgaggcc gtccgaattt gaatcggagt ctcaggctcc caaagcccga aggatggacc
    10861 aagctacccc acggcccctc ggcggcggaa ttgaacgtcc ggtaataaat agttgcttac
    10921 ctggcaagga atatataatc aacaatctca agcacctctc atgaaaaagg cctgggtggc
    10981 gatggtaatc gtgggagcgg tggtcgccat gctcctgttg tactatctgt taggaggctt
    11041 cgtccaggac ccctccggtt tccaggagga cgatctccag gctccgttcg tcagcgacgt
    11101 agtgcggaac gatgagtatc caggtccact gagcggatcg aactatccca tgcacgttca
    11161 gccgtcggtc agctacggtc ttctggtcta cgctgatttc ggaggggtgc tggaactttt
    11221 catggagaac gaagggagca acgaagttta cgttcaccac tactacgtct tttgggaggg
    11281 tggcaatgag acctttcagg tcaactgctc ccgcctgata tcctccggtg aggtgaaagg
    11341 tctgggtgag ctttatttcg ccggaccggg cgaacccgga ccagccactc tggaggtatg
    11401 ggccgaggtt tggacgtcct ctcccaacgg tatgctgtgg gacgaccagg gcgagatgct
    11461 catcagcacc atcgatctca atgtggtgga ggagggatcg ctgcgcgagt ggaaagtgga
    11521 gcggaaccct gttcaatact acaataaggt gaacggattg atcgatctgg aagtggtatc
    11581 gtcgatggct agcgatgttc gttccgcggt ccccggcaac tacagccttt tgcaggtgat
    11641 cgaggcttac gagctcataa gccagagtat cgattatgcc gaggacgagg acaaccactg
    11701 gcagtctccc gccgaaacga tcgccctagg ttccggcgac tgcgaggacc actccctgct
    11761 gatggcatct ctgatcaccg ttctaggcgg caactgccgg gtgaacctca tcgccgggca
    11821 cgccttcccc tccgtttacg tcggcaacga ctcggtcatc ggtgaggtca tcgaaaccat
    11881 ccaggcctat tacggtaatc cggtgccggt gcactacacg gtggacgatc tgggctattg
    11941 gatgatcgtc gataccaatg ggctaccata cgtcggcggc tatccggcag cgtcgtcacc
    12001 tgccggaggt gccggtgggg tgaactggag ctccgatgac ggcgactgga tcaaactgat
    12061 agatgtgacc ggggagaccg tggacaccct gttctaggcg ccgcggccga ctatctcccg
    12121 caccgccctc ttgatggcct gggagctgtt catggtcggc tcccagctgt acgatcgaag
    12181 cttgtccgaa gatagcagca tgttcttcac gtccccgatc cagccccgcc cgccctgcac
    12241 gccgccggtc cattcgtaac gtacgccgcg cagacccatg acctcggtga cggtgtccgc
    12301 gatgtccttg accgacatcc ggtcgttcga acccagattg aacatctcga tcttgttccg
    12361 agcgtactcc gcgccgatga tcataccgcg cacgcagtcc tccacgtgca cgtacgactt
    12421 ggtggtacct ggttcggagc ccagtatctc cagccggccg gggtcggcct tgagcttgtt
    12481 ggtgaagtca tgaaggacgt tatgcgtgct tcgcgtcccc accacgttgg cgaacctgaa
    12541 tatcactccg ttcatgtcga aagagtgggc gtaggagctg atcagcgcct cgcaggccag
    12601 cttagtcgcc ccgtaaacgg agatgggcac cagcggacca tagttctccg gggtcgggat
    12661 aactgtcggt tcgccgtaca cggtggacgt tgacgggaac aggatgtcct tgacccctgt
    12721 gtccttcatg gcctccagca ctcgataggt gacctcgatg ttctgctggt atagcgagag
    12781 cgtgtccttg gcgccggaac gaacgtccgg attggcggcc aggtgcatga ccgcgtcggc
    12841 tcccttgaat atcggtctca ggtcatcttt cagcaggtcg gcctgcacga accggaagtc
    12901 cgtatatccc tcggcgttct ccatgaactc ccggcgaccg gcgctgaagt tgtccacgcc
    12961 gaccacatgg ttgcccatgg ccagcagcgc gtccgtcaga tggcttccga tgaacccggc
    13021 gcagcctgtg accacgatgt tacttcctct gatcttcatt ttaattttcc catccttctc
    13081 ttgatctccg cggccagcag aaccatggcc ttaccccggt gagacagctg gttcttcgac
    13141 gccaggtcca tctgggcgaa cgtaagttcc ccgccatcag gcacgaatat ggggtcgtag
    13201 ccgaagccgc cgctcccccg ttcctcgtaa attatgcgtc ccggcgatac accggtcacc
    13261 gagaactcgc caagctcgtc cgagcacacg ccaatgcaac actcgaagcg ggccttgcgg
    13321 tccagcccgt cgatcaggcg cagcatgcct tggcatccga tggtgtccat gacgtaggcc
    13381 gagtacacgc ccggaaaccc gttcagggac ggcacgaaca gaccggagtc atccagcatg
    13441 aagttccggt atccctcgct cttgagctgg gcgatgcatg agcggaccac gttctggagg
    13501 gtgtcggtct ggatctcctc gcagtcggcc tggaggagct cgatgttcac acccagtcgc
    13561 tccaggccgt gacggtactc ctccaacttg tgcttgttgg aggtgacaag tcccagcttc
    13621 aagcgtaccg ccccctctcc tcgatgtcct tgaccttggc caggacatct cttccgccgg
    13681 cgtgctcacg cacgtacgtt tcaacgatga tttcgtaagc gtacatcatg tcggaatggg
    13741 ccgattggaa cgcctccttg agcagatgca ggtccactcc catctcctcc aggctggcgg
    13801 ccttacttcc tagtgaaagg tctatgaaga agacccgtcc gtcctgaagt atcatgttgg
    13861 acgtcgtcag gtcgccgtgg gtcatgccat gggaatggag cctggcgacc atccgcccga
    13921 tctcctggga tatggctcgc acctcctccg cgctggcgtt cagcagggcg tccttggccc
    13981 tcggtccgac gatctcctgc atccagatct ccgctctctc catgtcgatg tcgtagacga
    14041 tcggcgtggg aactccgcag gaccgggcct cctggagcaa tctcgcctcc acccgggtgc
    14101 gatgtgaccg gagggactgg tccagggcgg gatggcggta ggacttagga actctgcttt
    14161 ttaccagcac ctgtcgtccc atgaactcgt cccggcggat ctccgcctcc gcccctctcc
    14221 tgatgacctt cacgactaag ggaagtcagt gcccggttat tatcctttca ccctccccct
    14281 ggagcttcca aatgctttcc gaggaggttc cgaagaactc gctcaggagc tcgacgggat
    14341 cgccctcggt gaagcgcagg tctggaggaa tcattttctg caccttcctc tccagatatc
    14401 tagggtcgag cagcaccacc gccgcccggt cctcctccct tcgtatcgca cggccgcagg
    14461 cctgcagcac ccggctcaac gcctcgtacg tttccagatc gtgcccatca ccgatcttgc
    14521 tggacgcgcg gaacagcatc tcctttcgct ccaggctcgg cggggtcaac ggcaggccgg
    14581 cgaccatcac cgccgagagg catccagcgg gaaggtccac cccttccgag aaggagccgc
    14641 ggatattgca gagcatgagc acctcccgtt cgccgcctaa caggtcggcc aggccgtccc
    14701 ggtccgcttt gctcatcagg ggactttcgg acagcagcat cttgcgctga ccgagccgcc
    14761 gcaacgtgcg gtggacggcg ctcatgtaaa cgtacgaagg aaggaacacc atcacgttac
    14821 ccggtacctg ttccgccagc tcgccgatgc gcaaagccat gtccatggtg gtctggtggc
    14881 agcgatcgcg gaagcgagtg ccgacgtccg gtatcgccag agctagcctg cgcgccgggt
    14941 cgaacggcga gggataggag cgacacatcg cctccgccaa acccatccgg gcggcgaaca
    15001 cctccggcgg gtggagcgtg ccgctcatga atatggcccc ttgacattcc tggaccacgt
    15061 tcctcaccaa caggtcgggc tccagaaagc gcagcgatat cctgttctcg atggggtagg
    15121 ccactcgcac cgccgaatct cccaatcgca tccagtctcc gaccatgggg tccgagtcct
    15181 ccaactcctc cggctccggt aatccgaaac ggtccagcag ggagcgtagc tcgcccagcg
    15241 gaatgaggcg gtggccccgg gacagcattt ccttccaaac cgctcgtaga ggatcctccg
    15301 cagcagggtc caggaccagg tcccggctga aggcgtccat tatcctgacc ggcaggttgt
    15361 gcgcctcgtc cgtcaccaga tgctgcttcc tggacgacga acggaagcga atgacgtcag
    15421 gcaggttacc gaacaccctg gacacgtcgc cgaccaccag ttccgctccg ctcgaggcca
    15481 tcttggccga tatgtaggga caggctcccc gcctcaggca cagggcaacg gcctcttgcg
    15541 cgtgcatcgg ccgggccaat atctccttgg cgcattttgt gatctttcca tcagcctgca
    15601 ggtgacatct tctcccatca aggcatggag ggcgagggcc gagagggcac atgctgtccc
    15661 tggacagcag gtccaccgtc gcaatgttcc ggggcatcat cttcaccgtc tcgatgatcg
    15721 cccggtgctg tgattgcctt ggnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15841 nnccgaataa gtggaaatat caacaagtcc gtaaccgttc taggtgagat agtgaagtac
    15901 accatcactg gggacaacct gcagttcgtc aacgtcgagt tcatgcccgg agagatgata
    15961 tactccgagg cgggaagcat gatctacatg agcggcaacg tccgcctgga gaccaaggcc
    16021 gccggggggt taatgggcgg attgaagaga gcggtgtccg gggaatcctt cttcgtgacc
    16081 aacttctacg ccgagggcgg acctggtctg gtgggcttcg gcggcagcgt cccgggtaag
    16141 tgcatggcca tcgacctccg gggaggaagg cagtggctgc tgcagaagac ggcgttcctg
    16201 gcggcagagg cccaggtgaa cctggacatc gccttccaga ggaagttcgg ggcggcgctg
    16261 ttcggcggcg agggcctggt cctgcagaag gtgcagggcg aaggcacggt tttcatctcc
    16321 ggctccggcg acttcatcga gtacaatctt ctgccagggc aggtcatgaa ggtgtccacg
    16381 gccaacgtcg cggcctggga agctagcgtc tcctacgaca tccagagcct aggcattaag
    16441 accgcgctgt tcggcggcga aggtctgttc gtgaccacca tgaccgggcc ggggcgcatt
    16501 gtgttgcagt ccatgaccat gtccaagctg gccaactcca tagttccgtt cctgcccaac
    16561 cgagggtgaa ggtacgtcca aggcctctga cgccaccatc gtggcgctgc tggtgatagc
    16621 catgataggc gtagccttgc tggccgtctg gtacctggac tgggtgttgg cggccatcat
    16681 cgtgctggtg gccgcggcct tcctcgtgct ggtgctggcg gccgttctgg gcgggttggc
    16741 catcattcca tactatttcg ccaagcgcgg acgggacacg cagcccgggt cctacacgtt
    16801 ggagcaggtc aaggacatca aggaccagga gaggaagtga acgtggagga gctcaggctg
    16861 gtccccttcc aatgtccgcc cctggacgaa atgctgtccg gcggcatcga gagcggatgc
    16921 ctgaccctga tctacgggga ggccgggacc ggcaagacca atctgtgcct gacgctagcg
    16981 aagaatctgg cgcaggaagg gcgtaagacg atctacgtgg actcggaagg catatcgctg
    17041 ctgaggctgc gcgatatcgc cggggacgac caggagcggg ttctcaagga ggtcctgatc
    17101 agcgaggtgc acagcctgga cgaccaggac cgtatgatcg gcaaggcgat caagctggcc
    17161 gaggggaacc cggacgttgg gctcatcgtg gtggactcca tgaccatgtt ctaccggttg
    17221 gcgagcaagg atgacgaacg agcggaacgc cgcgtgctgg ccgggcagag cgccaaacta
    17281 ttgacggccg ccaggaagct gaaccttccg gtggtggcga cctcccaggt gtacaccgat
    17341 gtggagaccg ggatgttcga ggcgttgggc gggaacgtcc ttcatcacaa cgccaagaca
    17401 ataataagga tcgagaagct aggccccggc aagcgccggg cggtgatcat gaagcaccgc
    17461 aacctggccg agggccgctt cggggtcttc tatctgaccg ataaagggat agaggcggaa
    17521 cctcagagct cccggcccac ggcgtagtcc accatctccc gcagcatctc cttctcctcc
    17581 gaatccttaa ggcaggatag caggtccttg gcgcgcttcg cgtaatccag ggcgaactgg
    17641 cgggcgtgct ctatggagcc gatgtcgtca aggagctgta cggcggcctt gacctgctcg
    17701 tcgctggcct tggcgtttcc caaggcgtcc gtcagcacgt gccggcgctt gtccttctcc
    17761 aggcgctcca gggcgtccac cacgatcagc gtacgttttc cgttgcggat atcggaaccc
    17821 acgggcttgc cgaccttctt ggcatcccct ttgatgccga ggacatcgtc ccatatctgg
    17881 aagcctatcc ccagcagtct ggcgtactcc ttcatgtcgg tgatctgctt ctccgagccg
    17941 tgaccgatta tcgctccgcc ctccgcggcg caggcgaaca gcacggccgt cttcttctcc
    18001 accatgtcca ggtactcctc cctggacacg gtcgggcggt cctcgttgtc cacgtcgatc
    18061 tgctgtccct cggcgaccaa gaacacggta tcggagaccg tgtgcagcaa tctgcgcagc
    18121 ctctccccat ctatatcggt agtcgccaga acatcgaagg cgatggcgaa tagtgcgtca
    18181 ccggcaatga tcgccgtagg ctcgtcgaag gcgatgtgca ccgccggccg accacgccgc
    18241 acggggtcct tatcgattac gtcatcgtgg accagcgtga agttgtgaat tatctccagg
    18301 gcgcatccga acgggagcgc ctccttgccg cgctttccga ccgcttccgc ggcgaggatg
    18361 gccatgaccg gtctcatacg ctttccgccc gcttccgggt agtggcgcat ggccttgatc
    18421 agcttctcgt gcttgccgcg ttccacgtat ctcatcaggg agcggtccac ctccttgatg
    18481 atatcgttgg tcctctgttg atggtccata tgtatcagtc ctccgaggcg gtgagccagt
    18541 cggcagtccg cccgcttacg atgacccgcc gctggcgcag ctcgtccacg ctgccgcagc
    18601 cggtcaggaa catggccgcc ttgagctcgg ccttcataat attgatctta tcaagcaccg
    18661 cctggctgga ttccatggcc tctgccagga ccgcccgggc gcaccctgcg gcattagctc
    18721 cgatcgccag tcccttggcc attctcaggc cgtcgtcgat accgccgctg gcgatgatct
    18781 ccagcccgac gtccgcttcc agcaccgctg ccggggcggg tatgccccag tcgaagaacg
    18841 tccgtcccag ggcggacgcc aataggttct cctgggctat cgcccgatgc atctccaccg
    18901 cggcgaagct ggtgcctccg accccggaga cgtccatgcc tcgaattcca gtgcccttca
    18961 gcaggagcgc cgtttccctg gatatcccgg ccccggtctc cttgaccatg gtcggcccct
    19021 cccgggctat ggcccgaatc ccgtccaggc atcccttggc gttcacgtcc ccgttaggct
    19081 gcaccacctc ttgcaggaag ttcagatgaa cggccatgat gtccgcgccc acgacctcct
    19141 gcgcacggag cacatcgtcc acggtgaacg cgctcttacc tttctgcttg accagctgag
//
LOCUS       DAOPZI010000028        18078 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_3248_length_18078_cov_8.393386, whole genome shotgun sequence.
ACCESSION   DAOPZI010000028 DAOPZI010000000
VERSION     DAOPZI010000028.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 18078)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 18078)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18078
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3248_length_18078_cov_8.393386"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..838)
                     /locus_tag="PKM11_06300"
     CDS             complement(<1..838)
                     /locus_tag="PKM11_06300"
                     /inference="COORDINATES: protein motif:HMM:NF015050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48149.1"
                     /translation="MDPSVKEVLSKTMLEGVETVWDRLEKQQPHCKFCEAGLSCQRCA
                     MGPCRIMGEGKNRGVCGAGADLIVSRNLLDQIATGAASHSDHGREVAETLLLAARGKA
                     PGYGIADEGKMRLLAKEYGLDAEGPLEKVAEGLALAMLEEYGTMKGELSMAKRMPLGT
                     YEMLKAAGLLPRSIDREIVEAMHRVHMGVGADYRNILTHGVRASLGDGWGGSMIGTEA
                     SDVLFGTPQIRNSKVNLGVLKHDHVNISLHGHNPVLSEMVVKAAALPEMKRRAEEQGA
                     KGI"
     gene            1064..>1989
                     /gene="metG"
                     /locus_tag="PKM11_06305"
     CDS             1064..>1989
                     /gene="metG"
                     /locus_tag="PKM11_06305"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HNX48150.1"
                     /translation="MERSKVFIGVAWPYANSAIHLGHVAGSLLPPDIFSRYHKLRGNR
                     VLMVSGSDQHGTPVTVRADKEGLTPQQVADRYHEINKKAIEDLGIEFSLFTKTHTENH
                     IQVVQEIFTSLLKKGHLEQRETLQYFCPSCDKFLPDRYVEGRCVKCGNESSRSDQCDK
                     CGTTFEVGEIADPICITCKCRPEMRETRHYFFKLTDFEQPLLSYVQGSDHWRSNVQLF
                     TQNWLESGLKDRPITRDMSWGVPVPLPGSEDKVIYVWFEAVIGYLSASKEWAKATGNE
                     DAWKEFWTDPSVKGYYFLGKDNIPFHTIIWPS"
     assembly_gap    1990..2089
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2090..3157
                     /locus_tag="PKM11_06310"
     CDS             <2090..3157
                     /locus_tag="PKM11_06310"
                     /inference="COORDINATES: protein motif:HMM:NF039287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HNX48151.1"
                     /translation="ELVATLGNYFHRVLSFTHKNFHEVPPFVAGLEAESKQVDDAISA
                     AMAEVEANVSTCQFKKGLKAIMDLAQFGNRFFDACAPWSLLKTDRVKCGGVLHLNLKI
                     VQALAVLGFPYLPFTTQRLWGFLANDGALGEGSWDLITKDLNVGRELPEPKPLYRKVE
                     IQREESPFSAFESLDLRVGLIESVSDHPNADKLMVLKVNIGRPIQLVAGLKAFYSKEE
                     LTGKKVVVITNLAPAKLRGVESQGMVLAAEAGDKVKVLTPAGPAEPGDRVNSGLSSGT
                     KVLSFTEFQAFTLRTGTVLNDQEAALDKKVKADTSGLVKGVQAAFFLPKEGSDIALPL
                     YTEKKVSIGVDGNLDNGAKVR"
     gene            3154..3816
                     /locus_tag="PKM11_06315"
     CDS             3154..3816
                     /locus_tag="PKM11_06315"
                     /inference="COORDINATES: protein motif:HMM:NF038032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HNX48152.1"
                     /translation="MKFDLHVHSSHSGDSKNQIEEVLDACVRKGLSGVAIMDHNSLEG
                     SRYAISLKREDILIIPGMEISSAKGHILAYNVQDEVPRGLEVAETIDRIRAQGGIAVA
                     AHPYRMWSGLGEEVTLSNDFDAIEIHNGRSTHNHNDLAAKLAVRMCKPFTAGSDSHEP
                     STVGKAYFVSSRDCHSADDVVREILSFDGETGGKHRPKADSVAYGVKCIGEWFGRGFK
                     KM"
     gene            complement(3817..4164)
                     /locus_tag="PKM11_06320"
     CDS             complement(3817..4164)
                     /locus_tag="PKM11_06320"
                     /inference="COORDINATES: protein motif:HMM:NF015232.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="HNX48153.1"
                     /translation="MRGLEEKDFEQMLKKVSALEGVVSAYVCSRAGNYVIGNTPKFAD
                     RNMYAAITSLAYGTAEQVGHEMNDDLRYVSLRFSEKNLLVVAMGPRHLLGLLIEGRAD
                     QEQVLNKVRPLIT"
     gene            4271..5413
                     /locus_tag="PKM11_06325"
     CDS             4271..5413
                     /locus_tag="PKM11_06325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48154.1"
                     /translation="MPPVSLRSILPISAKGRTEADRIEPILVESLASPISLERKHMES
                     RVLRATKDDPEGMVAALLRNTEAKNEAARESIRDLLDQISQSREGKAAVLENLSHPDQ
                     DVRKGIKTMMVRIWGEGTDSFAADYEQALLLMNLARSRDIFVDDIVTLAELVKVTLLE
                     GDRDKALEDISLVVELLKHRYRAVETMKNYLADMLKITPELSKLGMMSGRIEESLRVA
                     SRANKQRSFDYTKDIIDEKLREVETIDQVRSLGMSIREMLNEAPHIPLEQLNGMDVWM
                     IARLKELVSKGTDLNVTSRRMELIDLVGSFLRDEVFPYMRDKAQDRWSARDPSLLFAL
                     YTVGLICLKLLHEPLPMVAEELYVTYFREFEGSPNVKDVSWPSAVL"
     gene            5523..6773
                     /gene="ftsZ"
                     /locus_tag="PKM11_06330"
     CDS             5523..6773
                     /gene="ftsZ"
                     /locus_tag="PKM11_06330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HNX48155.1"
                     /translation="MTSSLVKNALANTKYEGTNSGKAEPVKQEPVESRPAPAKSSIDE
                     DLEKIAAQLDVCIKIIGCGGGGCNTINRCWEANINGAQLCAINTDAKHLLTVKAPRKI
                     LIGRSATRGLGAGAKPEMGEAAARESDGDIREFLNGSNIVFVTAGMGGGTGTGSAHYV
                     ARIAKEQIRALTIGVVTMPFKAEGTIRMENALDGLNKMRLICDTTIVIPNDKLLELVP
                     KLPVDAAFKVADEVLMQTIKGLTEIITKPGLVNLDYADIMTVMNEGGVAFVGIGEGNS
                     DEDDRVKSAVHEALTSPMLGEIELKDAKGALIRVVGGPDMTVGEAQRVAELVTNSVSP
                     RARIIWGCSIDPELEGVVKVLLIITGAKSKYIMSSRGAPVNMQNQNQGYQQQYQQPYQ
                     PQPQQQQYQQQRPRNRDDDIDFVR"
     gene            complement(6843..8762)
                     /locus_tag="PKM11_06335"
     CDS             complement(6843..8762)
                     /locus_tag="PKM11_06335"
                     /inference="COORDINATES: protein motif:HMM:NF010368.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HNX48156.1"
                     /translation="MAEVRLGKMHLRWCDHCNVPVLEDVKCGRCGNGTHHVEMTPPGD
                     ARPAFQHDIDFVRKHVDAQFGACSGEALLPDGQVYLFNKVPALDRMDEVIADGEVVIT
                     MRYDLGIGWRALPRVKAAAKIVPKASKNLVWADQGAVEPILGNQSLMAVGVNKVIGDF
                     QKGEEVIVLDPEGNALATGVARMSSDEMRNAERGAAVKVRWAERSVPPAERPKADWNI
                     AIEANVKVMERRVREGVEFVLKLAEEHADIPRVVSFSGGKDSLATLLLTREAGLDLPV
                     FFIDTGLEFPETVAYVHRLKDELRLDLVLGKAEEDAFFGNLEFFGPPGKDYRWCCKTN
                     KLGPTVKAIVEHYPNGVLSFIGQRRYESEQRSAKPRVWRNPWTPGQIGASPIQDWTSL
                     HVWLYTFKSGVSYNPWYENGLDRIGCFLCPASDMGDLDVARSSPTFERWDAFLRAYAE
                     RKGLGPEWVEHGLWRWKRVPPSVMEELKRNIPGFELVRKEVPRTGEGNLRLKMQDGFS
                     PCTLGFSIEGAFSRDLDLEQVSSVLNMVGEVEVGADEGWCSVGNVTIFREGALIAKGA
                     DQEKIKRNVEKVRRAVVKAEECVGCGVCIARCKEGALVLMQGKVRVEATRCIHCGDCF
                     EPCPAISFGDAAFDF"
     gene            8907..>9196
                     /locus_tag="PKM11_06340"
     CDS             8907..>9196
                     /locus_tag="PKM11_06340"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="catalyzes the transamination of pyruvate or with
                     glutamate; activity is seen with alanine, glutamate, and
                     aspartate with either 2-oxoglutarate or pyruvate as the
                     amino acceptor; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine aminotransferase"
                     /protein_id="HNX48157.1"
                     /translation="MKATARTMGISYAIREMLLPARELEKQGHKIIKLHIGDPNKFDF
                     ETPKHVRDALCAAVEKCDNGYEESEGNVELRRAIIEKENKKNHIDLGLKDMVV"
     assembly_gap    9197..9296
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <9297..9892
                     /locus_tag="PKM11_06345"
     CDS             <9297..9892
                     /locus_tag="PKM11_06345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX48158.1"
                     /translation="FVISDEIYDLMTFEGEHYSPATLAKDVPVILVNGFSKVDLLPGW
                     RLGYAAFHDTTGQLDEIEEAVHKQARLRLSANAPCQMAVIEALKHPKDHLEGMRSKLK
                     ARGEFAYKRVNEIPGLSCVKPQAAFYMFPKIESNHWKTDKDFVLDILHQSHVLLVPGS
                     GFCPEYGKGHFRMVFLPNEDILGQAFDQIETYMRKVA"
     gene            complement(9941..10351)
                     /gene="ribH"
                     /locus_tag="PKM11_06350"
     CDS             complement(9941..10351)
                     /gene="ribH"
                     /locus_tag="PKM11_06350"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HNX48159.1"
                     /translation="MPRYNIGIVVSEFNYDITSMMLERAKSHAEFLEANVTKVVHVPG
                     VFDIPLAVKMMLKDNAIDGVVTLGCVIEGETEHDQIIIQNAARKVTDLSVEFMKPVAL
                     GITGPGMTRLQAEDRIENAKNAMESCVKMLKRLY"
     gene            complement(10354..10818)
                     /gene="ribC"
                     /locus_tag="PKM11_06355"
     CDS             complement(10354..10818)
                     /gene="ribC"
                     /locus_tag="PKM11_06355"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HNX48160.1"
                     /translation="MKTIGIADTTFARTDMGGAAIDELKNYGTGYKVIRRTVPGIKDL
                     PVAAKILLDEGCDIVMALGMPGSKPTDKMCAHEASTGIIAAQLATNKHIIEVFVHEDE
                     ADESKLAWLMEQRSREHARNAYDMIFKPERLIKNAGRGLRQGYEDVGPVRER"
     gene            complement(10818..11264)
                     /locus_tag="PKM11_06360"
     CDS             complement(10818..11264)
                     /locus_tag="PKM11_06360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="HNX48161.1"
                     /translation="MTRVMATGVFDILHPGHLRYLQEARDQGDELVVVVATDSTVRRR
                     KHEPITPENMRLELISALKMVDEAYLGSDGDMFGVVERIHPDIIALGYDQDFDEREIE
                     KTLLKRGLKVKVVRMSKHGEDLNGTRKIIGKIIEWYSKNQSKVKED"
     gene            complement(11271..11969)
                     /gene="ribB"
                     /locus_tag="PKM11_06365"
     CDS             complement(11271..11969)
                     /gene="ribB"
                     /locus_tag="PKM11_06365"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HNX48162.1"
                     /translation="MSDEHIERALQDIRNGKLVLIFDSDDRERETDMTIASEFVTPAS
                     IREMRKNAGGLICTTAHHDICQKLDMPFLADVLECNHDRHPVLQLLAPNDIPYDTKSA
                     FSITINHRRTFTGITDNDRALTVSEFAKLAKETYSMSAEEARTAFGKGFRAPGHIHLL
                     NSTPQLLSKRKGHTELATAMMVMAGVTPSATICEMMGDDGNALSKEKAKRYADRFGLC
                     FLEGKDIIEYWKRR"
     gene            12089..13129
                     /locus_tag="PKM11_06370"
     CDS             12089..13129
                     /locus_tag="PKM11_06370"
                     /inference="COORDINATES: protein motif:HMM:TIGR02128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoglucose/phosphomannose
                     isomerase"
                     /protein_id="HNX48163.1"
                     /translation="MAEAMDDILGMRSLDPSNLLGQLTAFPDQLEWSRGVDFPKIEGA
                     RSVVICGIGGSAIAGDVLVDMLAPSIPVPLFVSRDVLLPGFAGKDTLAIVVSYSGNTA
                     ESLDQYEDAMRRGCRIAVITSGGKMETLAKANSQPMIKVPGGNQPRASMGYLLGSLAL
                     VMQRAGFGKAHEELLAAAPSLRSYLDTLSPRVPFSSNQAKRLAKAMSGNVPSFYAPRP
                     VRSVALRWQGQFNENAKMVAFSGEVPEMDHNQLVGWLEGGTGCHCRPVIFMSTDMRPT
                     VRRMAEVTLQMLNERGRDPMLVALPGNDLLSNLLQGIALGDMASYYLAIMKRVDPAPV
                     TAIKEFKARISQ"
     gene            complement(13119..17090)
                     /locus_tag="PKM11_06375"
     CDS             complement(13119..17090)
                     /locus_tag="PKM11_06375"
                     /inference="COORDINATES: protein motif:HMM:NF024487.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4011 domain-containing protein"
                     /protein_id="HNX48164.1"
                     /translation="MDGTEQLVSKKAEVWKGRLLDVSNRNPLVRFRKHKASVLTVALP
                     DASTLYRELDQGRQFTVISEPQAQEDMGTGRLLVSAQVPEQPVDRVLYNLRSKSRTYR
                     SDHGVNILFVAVGSLIWKEVGCDDLNESPLFLVPVALERQNSFSPYRLQPLDEDTVFN
                     PTLRKRLELDYRLKLPEFDLDNGFDLPTAFEDIRKAIPPASGWLVNASCHLALFHFSK
                     LLMYSDLDQGLLSLSSQPVIRALAGDPAALPPEPPAMPRPQEYDAKLRPEDSFQVLDA
                     DSSQQEAVQAALAGVSFVLQGPPGTGKSQTITNMIAELMANGKRVLFVSQKMAALDVV
                     QGNLEKCGLGDRCLELHDPKKNRADIIKEIATSLENLNRPRTTVTDVRDLATVRQELD
                     DYVKGVHAPRGRLGTDVYRMIGQYAALSEARDINFKLPAVLEVDQDRLGRMEGLVLRL
                     SQMNAAFRDPAHPWSGALVTEWSDRLQSKVQEELTAVIDARQKLLAAIPSLTSALELP
                     AQESLPDLRRLRQLYRDMADRPAVRREWLEGDLDALAAMTNDGALSYQDLTMREKGLL
                     GMGSRDILDLDGKTFRHRYEVEYAGALRILNGGYRRDMKILQAISGRQLSFDEAKYLV
                     RAVDDYQSSLANWKVKRDNLLTAHRGVFSGDGAELPSLLERINWTRRFRSAHALFLNG
                     RVMDYLTSEVVPQQVQEGAVDLEMYLGRFDSALNVFASRFSQELRLSGRPVRDAVLKD
                     LEQWTDQAWVSRYRYQEWLDLASLLDGMKALGLGDLARELREKDVPPEGLVKAFQRRF
                     HRSWIEEALASDPVLSRFRRDHQTGLIDRFNELDKLHVERGRYRVQARVEENLQKRRE
                     GSDHSVLLKQETEIARLSKLKRQRKAMRSMLSECWDLIGLLKPCMLMSPMSVAQFLDR
                     ERTMFDTVIFDEASQICPEDAIGSIARGRQVIVVGDSKQMPPTSFFALSGDDEEEEPD
                     LESILDECETCGMSRRMLMWHYRSKDESLIAFSNHQFYGGKLNTFPSSIFGRQGFGLH
                     HVYVPSGVFDRGRSRTNRVEAEVVAKMVHDHYAKKNGESLGVIAFSEAQMEAIDRALD
                     EMRKDDRDLDAILSSEEGEPFLLYNLENVQGHERDRIILSVGYGKDESGKFALNLGPL
                     NRDGGERRLNVAITRAKLSLDIVSSIRSDDIDLSGSRSKGALLLKQYLAFAESGGDRR
                     ALPLSPGKHEEITPFEEQLSKALQARGHKVRMNVGTSDYRVDLAIEDPQEEGKFLLGI
                     ECDGPHYVSGLTVRDRDRTRQGQLRRLGWKLHRVWSVEWFRNPEGELDRIEEALRSVR
                     TTG"
     gene            17212..>18078
                     /locus_tag="PKM11_06380"
     CDS             17212..>18078
                     /locus_tag="PKM11_06380"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HNX48165.1"
                     /translation="MKEDAYWIRDQVQKHNKWFEESIPMIASENLMSPLAKEMMISDF
                     HDRYAEGLPGKRYYNGNIYVDQVEIKCLELAQRIFKCQFADVRPISGTVANMAALMAL
                     IQPGETMTCTSLDHGAHISTAKFGAVGFRGVNTATYPFDTHDMVIDVDGAAKLIREVK
                     PKVVQFGLSVFLFPAPVKELAEVAAEVGAPVWYDGAHVLGLIAGGKFQDPLHEGANVL
                     TASTHKTFPGPNHGIVLGHNLSEELGKKLNSAVFPGVTSSHHLHAMAALAVTMAEWEI
                     YGEKYAAQVCKNA"
BASE COUNT         3547 a         5561 c         5144 g         3626 t
ORIGIN      
        1 tgatcccctt ggcgccctgt tcctcggccc ggcgcttcat ctccggcaag gccgctgcct
       61 ttactaccat ttccgaaagc acgggattat gtccgtggag cgagatgttg acgtggtcgt
      121 gcttcagtac gcccaagtta accttgctgt tgcgtatctg cggcgttccg aacagaacgt
      181 cgctcgcctc tgtaccgatc atcgacccgc cccagccgtc tcccaaagaa gctcgaacgc
      241 cgtgcgtcaa tatgttccga tagtcggcgc cgacacccat gtgcacccgg tgcatcgcct
      301 ccacgatctc ccggtctatg gagcgcggta agagcccggc ggccttcagc atctcatagg
      361 ttccgagggg cattctcttg gccatgctca gttcaccctt catcgttcca tactcctcaa
      421 gcatagctaa tgcgagcccc tcggccacct tctccagcgg gccttcggcg tccaggccgt
      481 actccttggc cagcagcctc atcttcccct catctgctat tccgtatccc ggggcctttc
      541 cccgagccgc aaggagtaag gtttccgcga cctctctgcc gtgatcagag tgggatgccg
      601 ctccggtggc tatctggtcc agcaaattcc tggaaacgat aaggtccgcc ccggcgccgc
      661 aaaccccccg gttcttaccc tcgcccatta tcctgcaagg gcccatggcg catcgttggc
      721 acgacaggcc ggcttcgcag aacttacaat gcggctgttg cttctccaaa cggtcccata
      781 ccgtctccac accttccagc atcgtctttg acaggacctc cttcactgaa gggtccatag
      841 cccgttcctc aaccttcgcc ggcaccttgt ccggggtgac atggtcagga ggcgttcgaa
      901 tgcattccac tgttattatc tccaactctg aatcatctga catcggacca cccattgcca
      961 tcctaacgat ggttattgta atgtttgaga attcggcata tattatactg cccatttatc
     1021 cactgacggc aaggttatat cggaccaatc cattccaccg ccgatggagc gttccaaggt
     1081 attcataggc gtggcctggc cgtacgccaa cagcgcgatc cacttagggc atgtggccgg
     1141 gtcgctgctt ccccctgaca tcttctctcg ttatcacaag cttcgcggaa accgggtgct
     1201 catggtctcc ggttcggacc agcacggaac tcccgtgacg gtccgggcgg acaaggaagg
     1261 tctgaccccg cagcaggtgg cggaccgcta tcatgagatc aacaagaagg ccatcgagga
     1321 cctgggcatc gagttctcgc tctttaccaa aacgcacacc gagaaccaca ttcaggtggt
     1381 ccaggagata ttcaccagcc tattgaaaaa ggggcatctg gagcagaggg agaccctgca
     1441 gtacttctgt ccctcctgtg acaagttcct acccgaccgt tacgtggaag gcaggtgcgt
     1501 caaatgcggc aacgagagca gccgcagcga tcaatgcgac aagtgcggaa cgacgttcga
     1561 ggttggcgag atagcggacc cgatatgcat cacctgcaag tgccgcccgg agatgcgaga
     1621 gacccggcat tacttcttca agctcaccga tttcgaacag ccgctgctgt cgtacgtcca
     1681 ggggagcgat cactggcgat ccaacgttca gctgttcacc cagaactggc tggagtcagg
     1741 tctcaaggac cggcctataa ccagggacat gtcctgggga gttccggttc cgctgccggg
     1801 gtccgaggac aaggtcatct acgtctggtt cgaggcggtc atcggttatc tgtcggccag
     1861 caaggaatgg gccaaggcga ccggcaacga ggatgcctgg aaggagttct ggaccgatcc
     1921 ctcggtgaag ggctactact tcctggggaa ggacaacatt ccgttccaca ccataatctg
     1981 gccctccatn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng agctggtggc
     2101 gacgctaggc aactacttcc accgggtgct gagcttcacc cacaagaact tccacgaggt
     2161 tccgccgttc gtcgcgggac tggaggcgga gtccaaacaa gtggatgacg ccatatccgc
     2221 ggccatggcc gaggtggaag cgaacgtatc cacctgtcag ttcaagaaag ggctgaaggc
     2281 gattatggac ctggcccagt tcggcaatcg cttcttcgac gcctgcgctc cctggagcct
     2341 gctcaagacc gaccgggtca agtgcggcgg cgtactgcat ctgaacctga agatcgtgca
     2401 ggccttggcg gtgctgggct tcccctacct gccgttcacc acccagaggc tctggggatt
     2461 cctggccaac gacggtgcgc taggcgaggg gtcctgggac ctgatcacca aggacctcaa
     2521 cgtcggccgt gagctgccgg aaccgaagcc gctgtaccgc aaggtggaga tccagaggga
     2581 ggaatcgccg ttctcggcct tcgagtccct ggacctgcgg gtcggtctca tcgaatccgt
     2641 gagcgaccat cccaacgccg acaagctgat ggtgctcaag gtgaacatcg gccgcccgat
     2701 acagctggtg gccggtctaa aggcgttcta cagtaaagag gaactgaccg gaaagaaggt
     2761 ggtggtgatt accaacctgg cgccggcaaa gctccgaggg gtggaatcgc agggcatggt
     2821 cctggccgcg gaggccggag acaaggtcaa ggtgctcact cccgccggtc ctgcggagcc
     2881 gggcgaccgg gtcaacagcg gactaagttc gggaaccaag gtcctcagct tcacggagtt
     2941 ccaggccttc acgctaagga ccggcaccgt cctgaacgac caggaggccg ccctcgacaa
     3001 gaaggtcaag gcggacacct ccggtctcgt caaaggcgtt caggccgcct tcttcctgcc
     3061 taaggaggga tcggacatcg cgttgccgct atacaccgag aagaaggtca gcataggcgt
     3121 ggacgggaat ctggacaacg gggcgaaagt gagatgaagt tcgacctgca cgtgcattcc
     3181 agccattccg gcgattccaa gaaccagatc gaagaggtgc tggacgcatg tgttaggaag
     3241 ggcctatccg gggtggccat catggaccac aactccctgg agggctcccg ctacgccatc
     3301 tccctgaaga gagaggacat actcataatc ccgggaatgg agatatcctc ggccaaaggt
     3361 cacatactgg cctacaacgt tcaggacgag gtcccccgcg ggctcgaggt ggcggaaacg
     3421 atcgaccgaa taagagcgca gggagggatc gccgtcgccg cccaccccta ccggatgtgg
     3481 tccgggttgg gcgaagaggt caccctgtcc aatgatttcg atgccatcga gatacataac
     3541 ggccgttcca cgcacaacca taacgatctg gccgcaaagc tcgcggtcag gatgtgcaag
     3601 cctttcaccg ccggcagcga ctcgcacgaa ccgtctacgg taggcaaggc ctatttcgtg
     3661 agctcaaggg actgccattc cgcggatgac gtggtcaggg aaatattgtc gttcgatggg
     3721 gagaccggcg gaaagcaccg gccgaaggct gactcagtag cttatggcgt caagtgcatc
     3781 ggcgagtggt tcggacgcgg cttcaagaaa atgtgatcag gtgatgagcg gacgtacctt
     3841 gttcagaacc tgttcctgat cggcgcgtcc ttctatcaga agcccgagca gatgcctagg
     3901 tcccatggcg accaccaaca ggttcttttc cgagaagcgc agggacacat aacgaaggtc
     3961 gtcgttcatc tcatgcccta cctgttccgc ggtcccgtag gccagcgagg tgatggccgc
     4021 gtacatgttg cgatcggcga acttaggagt gttaccaatt acgtagttgc cggcccggga
     4081 gcagacatag gccgatacca cgccttcaag ggcggacacc ttcttcagca tctgttcaaa
     4141 atccttctcc tccaagccac gcatctcccg agagaaatat ggcaaatgga aataaagtct
     4201 ttgcccattg gttctctgac aaggatgcgt aaaacaaaag gacttattgg accaattcca
     4261 taacggtcat atgcctccgg tctcgctgcg cagtattctg cccatatccg ccaaggggag
     4321 gaccgaggca gatcgtatcg aaccgatact cgtggaatcc ctggcctcgc ccatatcgtt
     4381 ggagaggaag cacatggagt cccgggtcct cagggcgacc aaggatgatc cagagggcat
     4441 ggtggcagct ctgctccgca acaccgaggc caagaacgag gccgctcggg aatccattcg
     4501 cgaccttctc gatcaaatat cacagagtag ggagggcaag gcggcggtcc tagagaacct
     4561 ctcgcacccc gaccaggatg tcaggaaggg catcaagacc atgatggtcc gcatctgggg
     4621 cgaggggacg gactcctttg ccgccgatta tgagcaagcg ttgctgttaa tgaacctggc
     4681 gcgcagccgg gacatattcg tggacgacat cgtcacactg gccgaactgg tgaaggtgac
     4741 ccttctcgag ggggaccggg acaaggcgct ggaggacatc tccctggtcg ttgagcttct
     4801 gaagcaccgc taccgagccg tggagacgat gaagaactat ctggcggaca tgttgaagat
     4861 aactcctgag ctatcgaagc tgggcatgat gagcggcagg atcgaggagt cgcttcgcgt
     4921 cgcgtcccgg gccaacaagc agcgttcgtt cgattacacc aaggatataa tcgacgagaa
     4981 gctgcgggag gtggagacca tcgatcaggt ccgttcgcta gggatgtcca tccgggaaat
     5041 gctgaacgaa gcgccgcaca ttccgctaga acagctgaac ggtatggacg tctggatgat
     5101 agcccggctc aaggagctgg tgtccaaggg gaccgatctc aacgtcacct cccgccgtat
     5161 ggagctcatc gatctggtgg gttccttcct cagggacgag gtcttcccct atatgcgtga
     5221 caaggcccag gaccgatggt cggccaggga cccttcgctg ctcttcgccc tgtacacggt
     5281 cggactgata tgcctcaagc tgcttcacga accgttgccg atggtggccg aggagctata
     5341 cgtgacctat ttccgggagt tcgaggggtc gcctaacgtt aaggacgtct cctggccctc
     5401 ggccgtcctg tgatccggtc gccttgttct cgtctgacac ccgtcatccc ttgtccaggc
     5461 ctttaaaatt cagtaaaata tatatttgcg tttttcgtta tcctacctag agggatgcac
     5521 ttatgaccag ttcattggtt aagaacgctt tagcgaacac taagtatgaa ggaacgaaca
     5581 gcggcaaggc cgagcccgtg aagcaggagc cggtcgagtc gaggccagca cccgccaagt
     5641 cctccatcga tgaggacctg gagaagatcg ccgcccaact cgacgtgtgc ataaagatca
     5701 tcggctgcgg cggtggcgga tgcaacacca tcaaccgctg ctgggaagcg aacattaacg
     5761 gagcccagct ctgcgccatc aacaccgatg ccaagcacct gctgaccgtc aaggccccgc
     5821 gcaagatcct gatcggaagg agcgccaccc gcggcctagg cgcaggagcc aagccggaga
     5881 tgggagaggc ggccgcccgc gagagcgacg gcgacatcag ggagttcctg aacggctcta
     5941 acatcgtgtt cgtgaccgct ggaatgggcg gcggtactgg aaccggttcc gctcactacg
     6001 tggccaggat agccaaggag cagatccgcg ctctgaccat cggagtggtg accatgcctt
     6061 tcaaggccga aggtaccatc cgcatggaga acgccttgga cggtctcaac aagatgaggc
     6121 tcatctgcga caccaccatc gtcataccga acgacaagct tctggagctg gtgcccaagc
     6181 tgccggtcga cgccgccttc aaggtggccg atgaggtgct gatgcagacc atcaagggtc
     6241 tcacggagat cataaccaag cctggcctgg tcaacctgga ctacgctgat atcatgaccg
     6301 tcatgaacga gggcggagtg gccttcgttg gtatcggaga gggcaacagc gacgaggacg
     6361 atcgcgtcaa gtccgcggtg cacgaggcgc tgacgtcccc tatgctgggc gagatcgagc
     6421 ttaaggacgc caagggcgcc ttgatacgcg ttgtcggcgg tccggacatg accgtcggcg
     6481 aggcccagcg cgtggccgag ctggtcacca acagcgtttc cccccgtgct cgcatcattt
     6541 ggggatgctc catagacccc gagctcgaag gggtggtcaa ggtactgctg atcatcaccg
     6601 gcgccaagtc caagtacatc atgagcagcc gcggtgcacc ggtcaacatg cagaaccaga
     6661 atcagggcta ccagcagcaa taccagcagc cttaccagcc acagccccaa cagcaacagt
     6721 atcagcagca gaggccgcgc aaccgggacg acgacatcga cttcgtgcgc tgatgcggag
     6781 ggggtcaacg agggctgcgc cgatcgaccc ggccaccgtc cactatatgt cgccggtggc
     6841 ctctaaaagt caaaagcggc gtcgccgaag ctgatcgccg ggcaaggctc gaagcaatcc
     6901 ccgcaatgga tgcatcgagt cgcctcaacg cgaaccttcc cctgcatcag cacaagtgca
     6961 ccctctttgc atctggcgat acacaccccg catccgacgc actcctcggc cttaaccacc
     7021 gcacggcgaa ccttttccac gttccttttt attttttcct ggtccgcacc tttggcgatc
     7081 aaggcgccct ctcggaatat cgtgacgttg ccgacggagc accatccctc gtccgcgccc
     7141 acctcgacct cgccgaccat gttcaggacg ctgcttacct gttccaggtc caggtcgcgg
     7201 gagaaagccc cctcgatgct gaatcccagc gtgcagggcg agaacccatc ctgcatcttc
     7261 agacgcagat tgccctcgcc ggtcctgggc acctccttac ggaccagctc gaagccgggt
     7321 atgttgcgct tcagctcttc catcaccgac ggcggcaccc tcttccaccg ccagagcccg
     7381 tgctccaccc attccgggcc tagccccttc ctctcggcgt aagctctcag gaacgcatcc
     7441 caccgctcga aggtgggact cgatctcgcg acatccagat cgcccatgtc cgaggccggg
     7501 cagaggaagc atcctatgcg gtccagcccg ttctcgtacc aggggttgta gctgacgccg
     7561 ctcttgaagg tgtatagcca tacgtgtaac gaagtccaat cctggatagg ggaggctccg
     7621 atctgtccgg gcgtccatgg gttgcgccag acgcgcggtt tcgctgaccg ttgttccgat
     7681 tcgtaacgtc gctggcctat gaacgataga actccgttag gatagtgttc cacgatggcc
     7741 ttgaccgtcg gaccgagctt gttggtcttg cagcaccagc ggtagtcctt tcctggcggc
     7801 ccgaagaact ccagattgcc gaagaaggcg tcctcttccg cctttccgag caccaggtcc
     7861 aacctcagct cgtccttcag acggtgaacg taggccaccg tctccgggaa ctccagcccg
     7921 gtgtcgatga agaacactgg aaggtcaagt ccggcctctc tggtcagaag taacgtcgcc
     7981 agggaatcct tccctccgga gaaggatacc acccgcggta tgtccgcgtg ctcctcggcc
     8041 agcttcagta cgaactccac gccctcccga acccgcctct ccatgacctt cacgttggcc
     8101 tcgatggcga tgttccagtc ggctttcggc ctctcggccg gaggaacgct cctctcggcc
     8161 cagcggacct tgaccgccgc gcccctttcg gcgttgcgca tttcgtccga ggacatgcgg
     8221 gcgacgccag tggccagggc gttgccttcc gggtccagaa cgatgacctc ctcgcccttc
     8281 tggaaatccc cgatgacctt gttgacgccc acggccatga ggctctggtt gccaaggatc
     8341 ggctccaccg ccccttgatc ggcccagacc aggttcttgc tggccttagg cacgatcttc
     8401 gccgccgctt taactctcgg cagggctctc cagccgatcc cgaggtcgta acgcatggtg
     8461 atgacgacct ctccatcggc gatgacctca tccatgcggt ccagggcggg taccttgttg
     8521 aacaggtaaa cttgaccgtc cggtagcaaa gcctcaccgg agcatgctcc gaactgtgcg
     8581 tctacatgct tccgcacgaa gtcgatatcg tgctggaaag caggcctggc atcgccggga
     8641 ggggtcatct ccacatgatg ggtaccgttc ccgcagcggc cgcatttgac gtcctccagt
     8701 accggtacgt tgcaatgatc gcaccaccgg aggtgcatct tacctaggcg gacctcggcc
     8761 atgtacgcgg ctagtgcagg aacccctata aaatgtatgt tcccttggta accgggtcct
     8821 cacggcgtcc cagacggcag gctccaacat cgtgaaggag aatcgaagtc taatatagca
     8881 gtaatttcat catcccgcct gataccatga aagccaccgc gcgcacgatg ggtatcagct
     8941 atgcgatccg ggagatgctg cttcccgcca gagagctgga gaagcagggt cacaagatca
     9001 taaagctgca tatcggggac cccaacaagt tcgactttga aacgccgaaa catgtaaggg
     9061 acgctctctg tgccgccgtg gagaagtgcg acaatggcta cgaggagtcc gaggggaacg
     9121 tcgagctccg tagggccatc atcgagaagg agaacaagaa gaaccacatc gacctgggcc
     9181 tcaaggacat ggtcgtnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnntgtt
     9301 cgtgatatcg gacgagatct acgacctgat gaccttcgag ggcgagcact actctcccgc
     9361 caccttggcc aaggacgtgc cggtgatact ggtgaacgga ttctccaagg tggacctgct
     9421 gcccggctgg cgtctgggct acgcggcctt ccacgatacc accggtcaat tggacgagat
     9481 cgaggaggcc gttcacaagc aagcccggct tcgcctgagc gccaacgcgc cctgccagat
     9541 ggcggtcatc gaagccctga agcaccccaa ggaccacctg gaagggatgc gcagcaagct
     9601 gaaggcccgc ggggagttcg cctacaagag ggtcaacgag atacccggcc tgagctgcgt
     9661 caagccgcag gccgccttct acatgttccc caagatcgag tcgaaccact ggaagaccga
     9721 caaggacttc gttctggaca ttctgcacca gagccacgtt ctgctcgtcc cgggaagcgg
     9781 cttctgcccc gagtacggca aggggcattt ccgcatggtg ttcctgccca acgaggacat
     9841 cctcggccaa gcgttcgatc agatcgagac ctacatgagg aaggtggcct gaggccgccc
     9901 ctcatttttt tttaaaaaaa taattatttt taaaaaggtt tcaataaagg cgtttcagca
     9961 tcttgacgca ggattccatg gcgttcttgg cgttctcgat gcggtcctcg gcctgcagcc
    10021 gggtcattcc cggtccagtg atcccgaggg ccaccggctt catgaactcc accgataggt
    10081 cggtcacctt acgggcggcg ttctgaatga tgatctggtc gtgctccgtc tcgccctcga
    10141 tcacacagcc cagggtgacc actccgtcta tggcgttgtc cttcagcatc atcttgaccg
    10201 ccagcggtat gtcgaacacg cccggtacat ggaccacctt ggtcacgttc gcttccagga
    10261 actcggcgtg cgacttggcc cgctccagca tcatgctggt tatgtcgtag ttgaactccg
    10321 agaccactat tccgatgttg tatcttggca ttttcatctc tccctaactg ggcccacgtc
    10381 ctcgtagccc tgtcttagtc cccggccggc gttctttatc agccgctcgg gcttgaatat
    10441 catgtcgtaa gcgttacgcg catgttccct ggaccgctgc tccatgagcc aggcaagctt
    10501 gctctcgtcg gcctcgtcct cgtgcacgaa gacctcgatg atgtgcttgt tcgtcgccag
    10561 ctgggcggcg attatgccgg tggacgcctc gtgcgcgcac atcttgtccg tcggcttgga
    10621 gccgggcatg cccaaggcca tgacgatatc gcacccctca tccagaagta tcttggccgc
    10681 cactggcagg tccttgatcc ccgggacggt gcgcctgatc accttgtaac cggtgccata
    10741 attcttcagt tcgtcgatgg ccgctccgcc catgtccgtc cgggcgaagg tggtgtccgc
    10801 tatgccgatg gtcttcatca gtcctccttg accttcgatt ggttcttaga ataccactcg
    10861 atgatctttc cgatgatctt gcgcgtcccg ttcaggtcct cgccgtgctt ggacatccgg
    10921 acgaccttga ccttcaaacc cctcttcagc agggtcttct cgatctctcg ctcatcgaag
    10981 tcctggtcgt atccgagggc gattatgtcc gggtgtatcc gttccacgac cccgaacatg
    11041 tccccatcgc ttcccaggta cgcctcgtcc accatcttca gggcggagat gagctcgagc
    11101 cgcatgttct ccggggtgat cggctcatgc tttctccttc gtacggtgga gtccgtggcc
    11161 accaccacga ccagttcgtc cccttggtcc cgggcctcct gcagatagcg taggtgccct
    11221 ggatgcagga tatcgaacac gccggtggcc atcaccctgg tcattcctaa ttaccgcctc
    11281 ttccagtact ctatgatgtc ctttccttcc aggaagcaaa gtccaaaacg gtccgcgtac
    11341 cttttagcct tttctttgct cagcgcgttc ccgtcgtccc ccatcatctc gcagatggta
    11401 gcggatggcg tgacgccggc catgaccatc atggccgtgg ccagctcggt gtgtcccttg
    11461 cgcttgctga gcagctgcgg cgtggagttc aaaagatgga tgtgccccgg ggcccggaaa
    11521 cccttcccga aggcggtcct ggcctcctcg gcgctcatgg aataggtttc cttggccagc
    11581 ttggcgaact ctgaaacggt cagggcgcga tcgttgtcgg tgatcccggt gaacgtccgg
    11641 cggtggttga tggttatgga gaaggccgac ttggtatcgt acgggatatc gttaggcgct
    11701 agtaactgca gcaccgggtg gcggtcgtgg ttgcactcca gcacatcggc caggaatggc
    11761 atgtccaatt tctggcagat gtcgtggtgg gcggtggtgc atatcagtcc gccggcattc
    11821 ttgcgcatct ccctgatgga ggccggggta acgaactcgg aggcgatggt catgtccgtc
    11881 tcccgctccc ggtcgtcgga atcgaagatc aggaccagct ttccattgcg aatgtcctgc
    11941 aaagctctct cgatatgctc gtcgctcatg atggcgtcac caacacggag gttatagtat
    12001 attttttgcg ttactacaac tcaaatggta aatgaacctg gccagtcacg gctcactata
    12061 aaatattcca aggctcttac agttcacgat ggcagaggca atggacgata tcctgggcat
    12121 gaggtcactg gacccctcta acctgctggg acagctaacc gcgttccctg accagttgga
    12181 gtggtcgaga ggcgtcgatt tccccaagat cgaaggggcc cgcagcgtgg tgatctgcgg
    12241 tatcggcggt tcggccatcg ccggagacgt gctggtagac atgctggcac cttccatccc
    12301 cgttccattg ttcgtctcgc gcgacgtact gctgcccgga ttcgccggta aggacactct
    12361 ggccatagtg gtgagctatt ccggcaacac cgcggagagc ctggaccagt acgaggacgc
    12421 catgcgccgg ggatgccgca tcgcggtcat cacctccggg ggcaagatgg agacgctggc
    12481 caaggccaac tcccagccca tgatcaaggt cccgggggga aaccagcccc gggcctccat
    12541 gggctacctc cttggctcgc tggcattggt gatgcagagg gcggggttcg gtaaggccca
    12601 cgaggagctg ctggccgcgg cgccgagttt gcgctcatat ctggatacct tatctcctcg
    12661 agttcctttc tcatccaacc aggccaagcg gctggccaag gccatgagcg gaaatgtccc
    12721 ctcgttctac gccccgcgtc cggtgcgctc cgtggcgctg cgatggcagg gacagttcaa
    12781 cgagaacgcc aagatggtgg ccttcagcgg ggaggtcccg gagatggacc acaaccaact
    12841 ggtggggtgg ctggaaggcg gcaccggctg tcactgccgc ccggtgatat tcatgtccac
    12901 ggacatgaga ccgacagtaa ggcgcatggc cgaggtcacc cttcagatgc tgaacgagcg
    12961 cggtcgcgac cccatgttgg tggcccttcc gggaaatgat ctcctgagca atctgctgca
    13021 gggcattgcc ctgggggaca tggccagcta ctatttggcc atcatgaagc gcgtagatcc
    13081 cgccccggtc acggcgataa aggagttcaa ggcgcgcatc agccagtagt tctcaccgaa
    13141 cgaagcgcct cctctatccg gtccagctct ccctcggggt tgcggaacca ctccacgctc
    13201 cacacccggt gcagcttcca tcccagtctc ctgagctgtc cctgcctggt ccggtcccgg
    13261 tcccgcacgg tcagtccgga aacgtaatgc gggccgtcgc actcgatgcc cagcaggaac
    13321 ttgccctcct cttgcgggtc ctcgatggcc agatcgacgc ggtaatccga agtcccgacg
    13381 ttcattctca ccttgtgacc ccgggcctgc agcgctttgc tgagctgctc ctcgaatggc
    13441 gtgatctctt catgttttcc gggcgataag gggagcgcgc gtctgtcgcc tccggactcg
    13501 gcgaaggcca gatattgttt cagaagcagg gcgcccttgc tccgggaacc ggaaaggtcg
    13561 atgtcgtcgg agcgtatcga ggatactatg tccagggaca gcttggctcg ggttatcgcc
    13621 acgttcagcc ggcgttcccc tccgtcccgg ttcaacggac ccaggttcag ggcgaacttc
    13681 ccgctctcgt ccttgccgta gccgacgctg agtatgatgc ggtcccgttc gtgtccttgc
    13741 acgttctcca ggttgtacag caggaacggc tccccctctt ccgaggatag gatggcatcc
    13801 agatcgcggt cgtccttgcg catctcgtcc agggcccgat cgatggcctc catctgcgct
    13861 tcggagaagg cgattacgcc caggctctcg ccgttcttct tggcgtagtg gtcgtgcacc
    13921 atcttcgcca ccacctcggc ctccacccgg ttcgttctgc tccgtccgcg gtcgaagacc
    13981 ccgctcggaa cgtaaacgtg atgaaggccg aacccttggc gaccgaatat ggagctgggg
    14041 aaggtgttga gcttcccgcc gtagaactgg tggttggaga aggcgatcag cgattcgtcc
    14101 ttggagcggt agtgccacat gagcatacgg cgggacattc cgcaggtctc gcactcgtcc
    14161 agaatgctct ccaggtccgg ttcttcctcc tcatcgtccc ccgaaagggc gaagaaggat
    14221 gtcggcggca tctgcttgct gtccccgacc acgatgacct gtcggccgcg ggcgatggag
    14281 cctatggcat cctccgggca tatctgcgac gcctcgtcga agatgaccgt gtcgaacatc
    14341 gtccgttcgc ggtccaggaa ctgggctacc gacatcgggc tcatgagcat gcacggtttc
    14401 aatagtccta tcaggtccca gcactcgctc agcatgcttc gcatggcctt gcgctgcctc
    14461 ttcagcttcg agagccgggc tatctcggtc tcctgcttca gaagaacgct atgatcgcta
    14521 ccttcccttc ttttttggag gttctcctct acgcgggcct gcacccggta acgccctctc
    14581 tccacatgta gcttgtccag ctcgttgaag cgatcgatga gcccggtctg gtggtcccgg
    14641 cggaaacggc tcagcaccgg atcggaggcc aaagcctcct cgatccaaga gcggtggaaa
    14701 cgtctctgga acgccttgac cagaccttcc ggcggtacgt ccttctcccg cagctcccgg
    14761 gccagatctc ccaggcccag ggccttcatg ccgtcgagca gggaggccag gtccagccat
    14821 tcctggtagc ggtagcggga gacccaggcc tggtcggtcc attgttcgag gtccttcagg
    14881 accgcgtccc gtaccggacg gccgctcagc ctaagctcct gagagaagcg gctggcgaag
    14941 acgttcaggg cggaatcgaa ccggcccagg tacatctcca ggtccaccgc cccttcctgc
    15001 acctgctgcg gcacgacctc cgatgtcagg taatccatca cccgaccgtt gaggaacagc
    15061 gcgtgagcgg aacggaacct cctggtccag ttgatcctct ccaacagcga aggcagttcc
    15121 gctccgtccc cggagaagac gccccggtga gcggtgagca ggttatccct cttgaccttc
    15181 cagttcgcca gagaggactg atagtcgtcc accgcccgga ccaggtactt ggcctcatcg
    15241 aagctgagct ggcggccgga tatggcctgc aggatcttca tgtcccggcg atatcctccg
    15301 ttcaagatgc gcagcgcccc ggcgtactcc acctcgtaac ggtgacggaa cgtcttgcca
    15361 tcaaggtcca ggatgtcccg ggaccccatt cccagcagcc ccttctccct catggtcagg
    15421 tcctggtagg acaacgctcc gtcgttggtc atggccgcca aagcgtctag atctccctcc
    15481 agccactccc tgcgaactgc gggcctatcg gccatgtctc gatacagctg tctcaatcgc
    15541 ctcaggtccg gaagcgattc ctgggccggc agctccaggg cggaggtgag ggacggtatc
    15601 gccgccaaca acttctgacg ggcatctatg accgcggtca gttcctcctg taccttggat
    15661 tgtagtcggt cgctccattc ggtgaccaga gctccggacc agggatgggc gggatcgcgg
    15721 aaggcggcgt tcatctgcga tagcctgagc accagccctt ccatgcgtcc caagcggtcc
    15781 tggtccactt ccagcaccgc cggcagcttg aagttgatgt cccgagcctc gctgagcgcg
    15841 gcgtactgcc ctatcattcg gtaaacgtcc gtaccaagcc gaccgcgggg ggcgtgcaca
    15901 cccttcacgt aatcgtccag ctcctggcgc accgtggcca ggtcccggac gtccgtgacc
    15961 gtggtacgcg gccggttcag gttctccagg ctggtcgcga tctccttgat tatgtcggcc
    16021 cggttcttct tggggtcgtg cagctccagg cagcggtcgc ccagaccgca tttctccaga
    16081 tttccctgga ccacgtccag agcggccatc ttctgcgaga cgaacagcac tcgcttgccg
    16141 ttggccataa gttcggctat catgttggtg atggtctggc tctttccggt gcctgggggc
    16201 ccctgcagca cgaaactaac tccggccaac gcggcctgca ccgcctcctg ctggctggaa
    16261 tcggcgtcca gcacctgaaa ggagtcctcc ggtcttaact tggcgtcgta ctcctgcggc
    16321 ctcggcatgg ccgggggttc gggaggaagc gccgccgggt ctccggccaa ggctcggatc
    16381 accggctgag aggaaaggga cagaagcccc tggtccagat ctgaatacat cagcaacttg
    16441 gagaaatgga aaagggcgag atgacaggac gcgttaacta gccagccgga ggcgggcggg
    16501 atcgctttcc ggatatcctc gaaagccgtg ggcaggtcga aaccgttgtc caggtcgaac
    16561 tccggcagct tcaggcgata gtcgagctcc agccttttcc ggagggtggg attgaacacc
    16621 gtgtcctcgt ccaggggctg caatcggtac ggtgagaaag aattctgcct ctccaaggcc
    16681 accgggacca ggaacagggg cgattcattg agatcatcgc agcctacctc cttccatatt
    16741 agcgaaccga ccgccacgaa aaggatgttc accccgtgat cgcttcgata ggtccgggac
    16801 ttgctgcgca gattgtagag aacgcggtcc accggctgtt cgggcacctg ggcgctcacc
    16861 agcaaccttc cggtgcccat atcctcctgc gcctggggtt cggagatcac ggtgaactgc
    16921 cgtccctggt ccaattcccg gtacaaagtg gaagcgtccg gcagagcgac cgtcaacacc
    16981 gaggccttgt gcttccggaa cctgaccagg ggatttcggt tggaaacgtc cagcagcctg
    17041 cccttccata cctcggcctt cttggaaacc aactgctccg ttccgtccat ctctatccca
    17101 gcaagtcagg ggttgccagt tattaaaata ttttacaccc gtgttccttt ataaaaccgg
    17161 tctaggccaa cctatttaat cccccctttt gatggggttg caagtgacct tatgaaagag
    17221 gacgcctact ggatccggga ccaggtgcag aagcacaaca agtggttcga ggaatcgatc
    17281 cccatgatcg cctccgagaa cctgatgagc ccattggcca aggaaatgat gatatccgac
    17341 ttccacgacc gctacgccga gggacttccc ggcaagcgct attacaacgg caacatctat
    17401 gtggaccagg tcgaaataaa atgtctcgag ctggcccagc gcatattcaa gtgccagttc
    17461 gctgacgttc gcccgatatc ggggaccgtg gctaacatgg ccgcgctcat ggcactgata
    17521 cagcctggcg agaccatgac ctgcacttcg ctcgaccatg gcgcgcatat atccaccgcc
    17581 aagttcgggg ccgtcggttt ccggggcgtt aacaccgcca cctatccgtt cgacacccat
    17641 gacatggtca tcgatgtgga cggagccgcc aagctcattc gcgaagtgaa gccgaaggtc
    17701 gttcagttcg gcctatccgt cttcctgttc cccgccccgg tcaaggagct cgctgaagtg
    17761 gctgccgaag ttggcgcccc ggtctggtac gacggcgcgc acgttctcgg cctgatcgcc
    17821 ggcggcaagt tccaggaccc cctgcacgaa ggcgctaacg ttctcaccgc ttcgacgcac
    17881 aagaccttcc ctggaccgaa ccacggcatc gtcctcggtc acaacctgag cgaggagctg
    17941 ggcaagaagc tcaattcggc ggtgttcccc ggtgtgacgt ccagtcacca cctgcacgcc
    18001 atggccgccc tggccgtgac gatggccgag tgggagatat acggagagaa gtacgccgcc
    18061 caggtctgca agaacgcc
//
LOCUS       DAOPZI010000029        16880 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_3602_length_16880_cov_9.747994, whole genome shotgun sequence.
ACCESSION   DAOPZI010000029 DAOPZI010000000
VERSION     DAOPZI010000029.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 16880)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16880)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16880
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3602_length_16880_cov_9.747994"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            522..3512
                     /locus_tag="PKM11_06385"
     CDS             522..3512
                     /locus_tag="PKM11_06385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoB--CoM heterodisulfide reductase iron-sulfur
                     subunit A family protein"
                     /protein_id="HNX48166.1"
                     /translation="MVGGGIGGVQTSLDLAESGFKVYMVENKASIGGVMSQLDKTFPT
                     NDCSMCILSPKLVEAARHPMISMMTLTEVMGVEGEAGNFTVTLKKKPRYVREDRCVGC
                     GLCAEKCPSKVPAEYELGLMNRKAIYVAYAQAVPMKYAIDADKCLYLQKGKCGNCKKV
                     CPADAIDYEMKEEIQKIHVGAVVLAPGYELFDARLKKEYGYKEFKNVLNSLEFERVLS
                     ATGPYQGHVVRPSDHQTPKKVAFIQCVGSRDEKVGNPFCSSVCCMYALKQAIIAGEHS
                     TGLKSTIFFMDVRAFGKEFEDYAKRAENEYGIKMHRGTRVASVDETEGNNLLLRYSDG
                     ANVLAEEFDLVVLSAGFQPPAQAKALADRLGFKLNEFGFCETGVYSPLETTKKGIYVT
                     GAFSAPKDIPTTVAEASGAAAKAGAHVFNNRISIDTVVKETPETDVAGQEPRIGVFVC
                     DCGINIRGTVDCPSVVEYVKALPNVVYAVENKYTCSADTQEAIKKTIKEHNLNRVVVA
                     SCTPRTHEALFQSTIKEAGLNPFLFEMANIRDQCSWIHMHEPEKATEKAKDLTRMAVA
                     KSRFLEPLTKSKLGVNHSAVVVGGGLAGMTAALDIAAQGFKVDILEVTGAMGGNLANL
                     YTDEGGISPRKYIKDLEAKVRANHKISVHLNTTVMDVAGFVGNFKVKVTGDKEIETGA
                     IVVATGAKAYVPTEYNYGKDKKVVTQNDLEKALVEGSFHGKNVVMVQCVGSRNTEAPY
                     CSRVCCSKAVKNAIEIKKKDPKAQVYILHKDIRTYGFRETMYKEAGELGVKFIRYPED
                     KMPEMTSDGKIVVEDTVLGAPVQLSPDCLVLSVGIRPNDDNEELAKMCKVPLSKDKYF
                     LEAHMKLRPVDFATSGIYLAGLAHWPKFIDETIGQASGAASRALTIISKQYLETQGII
                     AAVNEMVCNGCGVCEPVCEYKAITIVGDPNTPERRKAVINEGLCMGCGTCVAACPSGA
                     LEQKGFKNNQILAQIDAALVGGGK"
     gene            3512..3964
                     /locus_tag="PKM11_06390"
     CDS             3512..3964
                     /locus_tag="PKM11_06390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase iron-sulfur subunit"
                     /protein_id="HNX48167.1"
                     /translation="MSNEAQAHSAPAEAGAWEPNLLVFCCNWCSYAGADLAGVSRLQM
                     PTNFRVIRTMCSARVDPEFVLRAFAKGADGVLILGCHPADCHYIGGNYRTRRRIALLR
                     VLLEQYGFNPDRLKLEWVSASEGMKFQQTIKEFNQRINELGTNPLNEE"
     gene            3990..5009
                     /locus_tag="PKM11_06395"
     CDS             3990..5009
                     /locus_tag="PKM11_06395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HNX48168.1"
                     /translation="MAKIRIAQYWAAGCGGCDVALLDIDEKILGVAEIADIVFWPIAV
                     DFKVKDVEAMPDGYITATLINGAVRNSENEHMAKLLRQKSALIVSFGSCACFGGVPGL
                     ANVTNKKDILEYVYWKTPSSDNKEHVLPTPHWHAPEGELEIPVLYDTVMTLDQVIDVD
                     YFMPGCPPTTNLINEFLGMVEKHVKEGAPLPPKGSVIASQKALCDECNRTRTVKKVDK
                     IHMPYEIDIDPEKCMLEQGVICLGPSTRAGCGAKCLEGNQPCRGCMGPTAEVLDQGGS
                     MLSALASIFAVGNDEGLLNEDDILEMMAQVKDPLGTFYAFTMPASIIKRKVKEKTATT
                     ASKEV"
     gene            5015..6547
                     /locus_tag="PKM11_06400"
     CDS             5015..6547
                     /locus_tag="PKM11_06400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe hydrogenase subunit alpha"
                     /protein_id="HNX48169.1"
                     /translation="MCPILMGQGTDKVEKTTEKRITIDPLTRLEGHGKIEIFLDDDGN
                     VANAYWQVPELRGFEKFCIGRSVDELNKLTSRLCGVCPGAHHICSTKALDHVFGVEPP
                     ETAKKLRELFYMAHYVHSHIAHFYALAAADFVLGPGAPKAERNILGVVGAVGLEIGGE
                     VIKNRSYAQKIQEMLGGKATHPVIGIPGGVAKSINEDERAKIEAMAKSCVEFGKFTNQ
                     LFADVVLKNQDYLNLIVNKDVYYHETYYLGTVDKNGKNNFYDGDQVMISPTGEEVARY
                     REGGRDYLKYIAEHTLPWSYEKFCYFKPVGWKGLVDGKDSGIYRATPLSRLNVTKGFT
                     TPLAQAEFEKYHGTFRDLGVKGPVHFTMATHWARVIEMLYAAERLLELSQDPEITGKH
                     VRNPVKEAGEGVGILEAPRGTLVHHYVADKNGITTDVNLVVGTTNNNGPMNLSVRKAA
                     TALIKNWNVSDGLLNAVEMAYRAYDPCNSCATHTLPGQMPMDAVIRRADGSVYKTVSR
                     NY"
     gene            complement(6612..7388)
                     /locus_tag="PKM11_06405"
     CDS             complement(6612..7388)
                     /locus_tag="PKM11_06405"
                     /inference="COORDINATES: protein motif:HMM:NF012376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HNX48170.1"
                     /translation="MPFEASPIPDRPVLELLGEERVLCVGDLHIGLEADMRFRGVIVP
                     SQTHRMEKELKDLAQGVDRLVIIGDVKHQVPGSTKQEHIEVPRFFNGLLNHYPRIDLV
                     KGNHDTDIERMLPSRVTVHDQGGFVLDDVGFVHGHAWPSEEVMSARLLVMGHNHPAVI
                     FEDGLHHNQVERCWVRCRFQATGDRYVRVPDEAIMLPAFNRSLGGGPVNFERPRMLGP
                     LLSNELLDLDNGQVYLMDGLLLGTVSSLRVKRRGYFRLED"
     gene            complement(7389..8063)
                     /locus_tag="PKM11_06410"
     CDS             complement(7389..8063)
                     /locus_tag="PKM11_06410"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HNX48171.1"
                     /translation="MKIAFISDIHSNLPALEAVFRDMSARNVAQVYCAGDILGYYTYP
                     DEVVDLLRRKGVNCIAGNHDRAVLVGTKGMNSIAAAAIEWTREHISSSTFDHIRDLPN
                     SIHRPVEEVMVAVHHGSPRHMSEYIFEEHVSDELLSVAGAKLLVLGHTHVPYQFQFPT
                     GHVINPGSVGQPRDGDPRASYAILDSSEWSFTNIRVAYDQRKVMDSVRENRLPEMLAL
                     RLLRGT"
     gene            complement(8076..9506)
                     /locus_tag="PKM11_06415"
     CDS             complement(8076..9506)
                     /locus_tag="PKM11_06415"
                     /inference="COORDINATES: protein motif:HMM:TIGR00196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HNX48172.1"
                     /translation="MIEREEVRVLDINSEFLGVPTEVLMENAGWALAQEITSRFGSGL
                     RIAIICGKGNNGGDGLVAARALTKSNRVRVFLALPPSEISTPESRINFEKVEELHKVF
                     AGEDLSGYDLIVDALLGVGSKGTPKGPYADLVKAINASGRPVVSADVPSGMGSALAVR
                     PTLTVTFHDRKTGMSEGHCGEIVVAEVGIPADAERFVGPGDLVHYPIPSLDSHKGQNG
                     RLLVIGGGPYTGAPALAGMSAYRIGTDLVFVACPDSVGDVVASYSPNLIVERLHGARL
                     DPRHGPQLKKLADGVDAVLLGPGLGDDPATLEAVRSFVPSCTKPMVLDADALKAMSGH
                     LGLLKGKAGVLTPHHRELELLLGHPVASDLDSRIDGAKTLALETGWTVLLKGRIDVIT
                     DGQRIKLNRTGNPGMSVGGTGDVLSGLTAGLLSKNVNPFNASRISAFINGSAGDLAFE
                     KNSYGLVATDLLERIPQVLRRGLSRI"
     gene            9602..9892
                     /locus_tag="PKM11_06420"
     CDS             9602..9892
                     /locus_tag="PKM11_06420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF211 domain-containing protein"
                     /protein_id="HNX48173.1"
                     /translation="MSEIKRLVLDVLKPHHPSIIDLANRLSVVEGVSGVNCTLDEVDQ
                     ETESIKITIEGVAINYEDVEEVIIDSGAVIHSVDSVSAGKKLVEEVETPQDR"
     gene            complement(9880..10173)
                     /locus_tag="PKM11_06425"
     CDS             complement(9880..10173)
                     /locus_tag="PKM11_06425"
                     /inference="COORDINATES: protein motif:HMM:NF014032.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle subunit SRP19/SEC65
                     family protein"
                     /protein_id="HNX48174.1"
                     /translation="MALDEDTAWVLWPEYFDRSRPRSQGRKVKKGLAINDPTVDLLSA
                     ALRQLGLQHKVEREKKYPANWFSSDGRILVEKTISKSALVKKVGELLIRSQRS"
     gene            complement(10190..10573)
                     /locus_tag="PKM11_06430"
     CDS             complement(10190..10573)
                     /locus_tag="PKM11_06430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8e"
                     /protein_id="HNX48175.1"
                     /translation="MALWQGRSKRKPSGGRLTLSRSKRRFEIGKEPVFTFVGSEKRQV
                     SRVRGANVKVRLLKAQFANVVDPTNNKTQKVKIIKVNTSLSNPNYVQRNIVTKGAVIQ
                     TELGPAKVTSRPGQDGSINAILVKE"
     gene            complement(10627..11265)
                     /locus_tag="PKM11_06435"
     CDS             complement(10627..11265)
                     /locus_tag="PKM11_06435"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HNX48176.1"
                     /translation="MGGRYLVLTDVHRREWVPAAARELMKEHSLDAVVLLGDLTHFGP
                     PQFAEDLITELETKCYAVPGNCDPLGTEAFIKRAGTSLHGVKMTIDGRTWGGLGGSNP
                     SIFRTPFEMPEEEISRLLEPIMEEGMVLVLHNPAYGTFDTTFSGLHVGSTAIAGAIDR
                     CKPSVVLSGHIHEDRGVERKDGIWYMNPGAAKDHYAGMMELEDEVRLTLLDL"
     gene            complement(11301..12212)
                     /locus_tag="PKM11_06440"
     CDS             complement(11301..12212)
                     /locus_tag="PKM11_06440"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: protein motif:HMM:NF018279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042500 - aspartic endopeptidase activity,
                     intramembrane cleaving [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="presenilin family intramembrane aspartyl
                     protease PSH"
                     /protein_id="HNX48177.1"
                     /translation="MRSARQYLVMTGMFLAVPALALLLIPGVPSGYRAFSDQNDPTNP
                     IMYIVLVLAMTGVLLLLIKRSKLGLLRAILFISMGLGLFSIGSLFAMLAGSAEIPSLA
                     FGAILAGSLMLLLLKFPRWYVVNGAGLVLGVGAALVLGLSLGILPSLILLVTLAVYDA
                     LSVYVTKHMLTLAEGVGNLGLPIVLIVPGKDGGQSKKLDLHDRSKDADRELMMMGLGD
                     AIIPSVLIVSAAANLSPVSSTNWPFPAMTVGVLTLAAVLLGFLSLMFFISKGRPQAGL
                     PFLNGFAIIGYATAYILVYQDLGFGFA"
     gene            complement(12273..12896)
                     /locus_tag="PKM11_06445"
     CDS             complement(12273..12896)
                     /locus_tag="PKM11_06445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2 subunit beta"
                     /protein_id="HNX48178.1"
                     /translation="MANDDYLSLLDRAKTQLPETIEKHERFVVPEPDVFQEGKTTVFR
                     NFGDVVDTLRREPEQILQYMLRELGTPGTMEGRRVVFKTRLTPTQIADKIQNYVDTFV
                     LCSECGRPDTHINKEDRILILECEACGAHRPVNVRKVQKPNEEGLREGGIYEMMIEDV
                     GKKGDGVARMFDYIIYVPGTVKGSRVKVKVAKITGKVAYGNVSIESA"
     gene            complement(12935..14548)
                     /gene="pyrG"
                     /locus_tag="PKM11_06450"
     CDS             complement(12935..14548)
                     /gene="pyrG"
                     /locus_tag="PKM11_06450"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HNX48179.1"
                     /translation="MKYIFVTGGVISGLGKGITASSIGRLLKSRGIKVTAIKIDPYLN
                     VDAGTMNPFEHGEVYVLDDGGEVDLDLGNYERFLDISLTSAHNITTGKVYKSVIEKER
                     TGEYLGKTVQIIPHITNEIKAHIVNVAEATGAEVCIVELGGTVGDIESMPFLEAVRQM
                     NQDLGKGRNCLFVHTTLVPVMGTVGEQKTKPTQHSVKELRAIGIQPDIIVARCKEPLE
                     ESIRHKISLFCDVPIEAVVTAADARSIYDVPMALEEQNLTDYVMQRFGLTAKTQELEE
                     WKAFANRINDQERTVRIACVGKYTNLADSYISHLESFHHAGAEAGTKVQVVFVDSEVV
                     QQYGITEELLGADGILIPGGFGTRGIEGKIATAKFARENRIPFLGVCLGFQIATIEFA
                     RNVLGMEGANSTEFDPDTPFPVVDLLPEQKNVKKMGATMRLGAQPVMVEEGSKAFELY
                     GKALIMERHRHRFEVNPKHIEELEKGGWKFTGRSADGVKMEIGEMTGYDYYIASQFHP
                     EFKSRPRKPSPLHYGLVRAAVARKYGGTQ"
     gene            complement(14757..16224)
                     /locus_tag="PKM11_06455"
     rRNA            complement(14757..16224)
                     /locus_tag="PKM11_06455"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01959"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01959"
     gene            16794..16880
                     /locus_tag="PKM11_06460"
     tRNA            16794..16880
                     /locus_tag="PKM11_06460"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16828..16830,aa:Ser,seq:gct)
BASE COUNT         3678 a         5030 c         4706 g         3466 t
ORIGIN      
        1 gaccaccttt cctaataaat cagttgcccc ctgattattg aaatccgtca tggacgatgg
       61 tcaaacggat tacggtcaaa acccgtttcc catacatgca tgctatttct tccgaatagt
      121 gaaacgataa aagcgaaaag ctcttaaacg gtaagcaatc acgagaacac catgtcctgc
      181 ctctcgacag aacacataat gttgaaatat ggacatttta atcccgaagg cactgctctg
      241 ttatcaggga tgagatccct gacgttccag gctccaggga tagacattcg tggaggtacc
      301 cattcgcctc aagggggcag gtatgcgaag ggtaggggac cacggtccta tattctggtt
      361 cggagtgggg ccctaatagg agggagaggc aactgagcgg tttaaagtca atattcggcg
      421 gattgttcga caagggatct aaaaaggaac aaacggccga aggatcgaaa gatgatacaa
      481 aaggaggagt gaatttggaa tcaaaaagcg gttctgtttt ggtggtaggg ggcggcatcg
      541 gcggtgtcca gacctctttg gacctggctg agtcagggtt caaggtctac atggtcgaga
      601 acaaggccag catcggcggt gtcatgtccc agttggacaa gaccttcccg accaacgatt
      661 gttcgatgtg catcctgtcg cctaagttag tagaggcagc gaggcacccc atgatcagca
      721 tgatgacctt gaccgaggtc atgggcgttg agggagaggc cggtaacttc acggttactt
      781 tgaagaagaa gccccggtac gtccgggagg acagatgcgt cggctgcggc ctttgcgcgg
      841 agaagtgtcc gtcaaaggtg cccgccgagt acgagctggg cctgatgaac aggaaggcga
      901 tctacgtcgc ttacgcccag gccgtgccga tgaagtacgc catcgacgct gacaagtgcc
      961 tttatctcca gaagggcaag tgcgggaact gcaagaaggt ctgtcccgct gacgccatcg
     1021 actacgagat gaaggaagag atccaaaaga tccacgtggg tgcagtggtt ctggcgcctg
     1081 gttacgagct attcgacgcc cgcctgaaga aggagtacgg ctacaaggag ttcaagaacg
     1141 tcctgaacag cctggagttc gagcgggtac tgagcgccac cggtccctac cagggacacg
     1201 tggtcaggcc gtccgaccac cagaccccca agaaggtcgc tttcatccag tgcgtcggtt
     1261 ccagggacga gaaggtagga aaccccttct gctcgtccgt ctgctgcatg tacgccctga
     1321 agcaggccat aatcgccggg gagcattcca ccggtctgaa gtccaccata ttcttcatgg
     1381 acgtcagggc ctttggaaag gagttcgagg actacgccaa gagggccgag aacgagtacg
     1441 gcatcaagat gcaccgcggg acccgcgttg cctccgtcga tgagaccgag ggtaacaacc
     1501 tgctcctgcg ctacagcgac ggagcaaacg tcctggccga ggagttcgac ctggtcgttc
     1561 tgtccgccgg cttccagcct ccggcacagg ccaaggccct ggccgaccgc ctgggattca
     1621 agctgaacga gttcggcttc tgcgagaccg gggtctacag cccgctggag accaccaaga
     1681 agggaatcta cgtcaccggc gccttcagcg cccccaagga catcccgacc accgtcgctg
     1741 aggccagcgg cgccgccgcc aaggccggtg cccacgtctt caacaaccgc atcagcatcg
     1801 ataccgtggt caaggagacc ccagagaccg atgttgctgg acaggaaccc cgcatagggg
     1861 tgttcgtctg cgactgcggc attaacatcc gcgggaccgt agactgcccg tccgtcgtgg
     1921 agtatgtgaa ggccctgccg aacgtggtgt acgccgtgga gaacaagtac acctgctccg
     1981 ccgatactca ggaagcgatc aagaagacca tcaaggaaca caacctgaac cgcgtggtag
     2041 ttgcttcttg cactcccagg acccacgagg ccctgttcca gagcaccatc aaggaggccg
     2101 gcctgaaccc gttcctcttc gagatggcca acatccgtga ccagtgctcc tggatacaca
     2161 tgcacgagcc ggagaaggcc accgagaagg ccaaggacct gacccgcatg gcggtagcca
     2221 agtcccggtt cctcgagccg ttgaccaagt ccaagctggg cgtcaaccac tccgccgtcg
     2281 tggtcggcgg tggactggcc ggaatgaccg ctgctctgga catagccgcc cagggattca
     2341 aggtcgacat cctggaggta accggtgcca tgggtggaaa cttggccaac ctgtacaccg
     2401 acgagggagg catctccccg aggaagtaca tcaaggacct ggaagccaag gttcgcgcca
     2461 accacaagat cagcgtgcac ctcaacacca ccgtgatgga cgtcgccggc ttcgtcggca
     2521 acttcaaggt gaaggtcact ggcgataagg agatcgagac cggagcgata gtcgtcgcca
     2581 ccggcgccaa ggcctatgtc ccgaccgagt acaactacgg caaggacaag aaggtggtaa
     2641 cccagaacga cctggagaag gccctcgtgg aaggcagctt ccatggcaag aacgtggtca
     2701 tggtccagtg cgtcggttcc aggaacaccg aggcgcccta ctgtagccgc gtctgctgct
     2761 cgaaggcggt caagaacgcc atcgagatca agaaaaagga ccccaaggcc caggtctaca
     2821 tcctgcacaa ggacatcagg acctatgggt tcagggagac catgtacaag gaggctgggg
     2881 agctcggagt gaagttcatc cgctacccgg aggacaagat gcccgagatg acctcggacg
     2941 gcaagatcgt ggtcgaggac accgtccttg gcgccccggt ccaactgtcc cccgactgcc
     3001 tcgttctgag cgtaggaata cgcccgaacg atgacaacga ggagctggcc aagatgtgca
     3061 aggtgcccct gagcaaggat aaatacttcc ttgaggcgca catgaagctg aggccggtcg
     3121 acttcgccac cagcggcata tacctggctg gactggccca ctggccgaag ttcatcgatg
     3181 agaccatcgg acaggcttcc ggagcggcct ccagggcact gaccataata tcgaagcagt
     3241 acctcgagac ccagggcatc atcgccgcgg ttaacgagat ggtgtgcaac ggttgcggcg
     3301 tgtgcgagcc agtgtgcgag tacaaggcca taaccatcgt gggcgacccc aacactcccg
     3361 agaggcgcaa ggccgtcatc aacgaaggcc tgtgcatggg atgcggaacc tgcgtggccg
     3421 cctgcccgtc cggagccctg gagcagaagg gcttcaagaa caaccagatc ctggcgcaga
     3481 tcgacgccgc tctggtcgga ggtggaaagt aatgtccaac gaagcacaag cccacagcgc
     3541 tccggcggaa gccggggcct gggaacccaa cctgttggtg ttctgctgca actggtgctc
     3601 ctacgccggg gccgacctgg ccggagtttc ccgtcttcag atgccgacca acttccgtgt
     3661 gataaggacc atgtgctccg ccagggtgga ccccgagttc gtcctgagag ccttcgccaa
     3721 gggagccgac ggcgtgctta tcctgggctg ccaccccgct gactgtcact acatcggtgg
     3781 gaactatcgc accaggagaa ggatcgccct gctccgcgtg ctgttggagc agtatggatt
     3841 caaccctgac cgcttgaagc tggagtgggt ctccgcatct gaggggatga agttccagca
     3901 gaccatcaag gagttcaacc agaggatcaa cgaactgggc acgaacccct taaacgagga
     3961 gtaaatctga cccccaagga ggaacaaata tggcaaagat aaggatcgca caatattggg
     4021 ccgccggatg cggaggctgc gacgtcgccc tattggacat tgacgagaag atcttgggtg
     4081 tcgccgagat cgctgacatc gtgttctggc ccatcgccgt cgatttcaag gtgaaggacg
     4141 tcgaggccat gcccgacgga tacatcaccg ccactctgat caacggagcg gtcaggaaca
     4201 gcgagaacga gcacatggcc aagctgctca ggcagaagtc ggccctgata gtctccttcg
     4261 gttcctgcgc ctgcttcggt ggagtacccg gactggccaa cgtgaccaac aagaaggaca
     4321 tcctggaata cgtgtactgg aagaccccca gctccgacaa caaggagcac gttctaccaa
     4381 cacctcactg gcacgccccg gagggtgagc tggagatccc ggtcctatat gacacggtca
     4441 tgaccctgga ccaggtaata gacgtcgact acttcatgcc cggctgcccg ccgaccacga
     4501 acttgatcaa tgagttcctg ggaatggtgg agaagcacgt caaggaaggc gccccgctgc
     4561 cccccaaggg ctccgtgatc gcttcccaga aggccctctg cgatgaatgc aacaggacca
     4621 ggaccgtcaa gaaggtcgac aagatacaca tgccttacga gatcgacatc gatcccgaga
     4681 agtgcatgct ggagcaggga gtcatctgcc tcggaccgtc taccagggcg ggatgtggcg
     4741 ccaagtgcct ggagggcaat cagccctgcc gcggatgcat gggaccgacc gccgaggtct
     4801 tggaccaggg cgggagcatg ctgagcgcgc tggcctcgat attcgccgta ggcaacgacg
     4861 agggactgct gaacgaggac gacattctgg agatgatggc ccaggtcaag gacccgctcg
     4921 gaacgttcta cgcgttcacc atgcctgcat cgatcatcaa acgtaaggtt aaggaaaaga
     4981 cagctaccac tgcttccaag gaggtctgaa tctaatgtgc cctatactga tgggtcaggg
     5041 aactgacaag gttgagaaga ccaccgagaa gcggatcacc attgaccccc tcacccggtt
     5101 ggaaggccac ggtaagatcg agatcttcct ggacgacgac gggaatgtgg caaatgccta
     5161 ctggcaggtg cccgagctca ggggattcga gaagttctgc atcggtcggt ccgtagacga
     5221 actgaacaag ctgacctcca gactttgcgg tgtgtgcccc ggcgcccacc acatctgttc
     5281 gaccaaggcg ttggaccacg tgttcggcgt cgaacccccg gagaccgcca agaagctgcg
     5341 tgagctgttc tacatggctc actacgtcca cagccacatc gctcacttct acgccctggc
     5401 cgccgcggac ttcgtcctcg gccccggtgc cccgaaggcc gagaggaaca tcctcggcgt
     5461 ggttggagct gtaggattgg agatcggcgg agaggtcatc aagaaccgct cctacgctca
     5521 gaagatccag gagatgctcg gcggaaaggc tacccacccg gtcataggta tcccgggcgg
     5581 tgtcgccaag agcatcaacg aggacgagag ggccaagatc gaggccatgg ccaagtcctg
     5641 cgtcgagttc ggaaagttca ccaaccagct gttcgctgac gtggtactga agaaccagga
     5701 ctacctgaac ctgatcgtca acaaggacgt ctactaccac gagacctact acctcggtac
     5761 cgtggacaag aacggcaaga acaacttcta cgacggtgac caggtcatga tctcccccac
     5821 tggggaagag gtcgccaggt accgcgaggg cggcagggat tacctgaagt acatcgccga
     5881 gcacactctg ccctggtcgt acgagaagtt ctgttacttc aagccggtcg gctggaaggg
     5941 actggtggac gggaaggaca gcgggatcta ccgcgccacc ccgctctcca ggctcaacgt
     6001 caccaagggt ttcaccaccc cgctggcgca ggccgagttc gagaagtacc acgggacctt
     6061 ccgcgatcta ggcgtcaagg gaccagtgca cttcaccatg gccacccact gggcccgcgt
     6121 gatcgagatg ctctacgccg ccgagaggct gctggagctg tcccaggacc ccgagatcac
     6181 cggcaagcac gtacgcaacc cggtgaagga ggctggcgag ggagtcggta tactggaggc
     6241 cccgcgcggc accctggtgc accactacgt cgcggacaag aacggcataa ccaccgacgt
     6301 gaacctggtc gtgggaacca ccaacaacaa cggccccatg aacctcagcg tccgcaaggc
     6361 cgccaccgct ctgatcaaga actggaacgt gtccgacggt ctgctgaacg ccgtggagat
     6421 ggcctatcgc gcctacgacc cgtgcaacag ctgcgccacg cacaccttgc ctggtcagat
     6481 gccgatggac gccgttatca ggcgcgccga cggttcggtc tacaagaccg tgtcccgcaa
     6541 ctactaaacc ccttatccct aaccttttcc ttttttcatt ttttcaagga tcggccgaag
     6601 gtcttttgag atcaatcttc cagacggaaa tatcctcttc tcttaactct cagcgaggac
     6661 accgttccca gcagaagccc gtccatgagg tagacctgtc cgttgtccag gtccaggagc
     6721 tcgttggata gcaaaggccc gagcattctg ggtcgttcga agttaaccgg gccgccaccc
     6781 agggaccggt tgaaggccgg taacataatg gcctcgtcgg gaaccctgac atatctatcg
     6841 ccggtcgcct ggaaacggca ccgtacccag catctttcca cctgattatg atgtaaaccg
     6901 tcctcgaata tgaccgccgg gtgattgtgt cccatgacca gaagccgggc ggacatgacc
     6961 tcctccgagg gccaggcatg accgtgaacg aaacccacgt cgtccagcac gaaacctccc
     7021 tgatcgtgga cggtgacccg cgaaggtaac attcgttcta tgtccgtatc gtgattgccc
     7081 ttcaccaggt ctatccgggg atagtggttc agaaggccat tgaagaaacg cggcacctcg
     7141 atatgctcct gcttggtgga accggggacc tgatgcttaa cgtcgccgat gatcactagg
     7201 cggtccactc cttgggccag gtccttaagc tccttctcca tgcgatgcgt ttgactggga
     7261 actatcacgc ccctgaaacg catatccgcc tcgagcccta tgtgcaggtc gcccacgcag
     7321 agcacccgct cctcaccgag cagctccagc accgggcggt ccggtatcgg cgaggcttca
     7381 aagggcattc aagtacctcg gagcagcctt aaggctagca tctccgggag gcgattctca
     7441 cgcacgctat ccatgacctt tcgttgatca taggccaccc ggatgttggt gaacgaccat
     7501 tccgaggagt cgagtatggc gtacgaggcc cggggatctc cgtcccgagg ctgtccgacc
     7561 gaccctggat ttatcacgtg gccggtcggg aactggaatt ggtacggtac atgggtgtgc
     7621 cctagcacca gcagcttggc cccagctacc gatagcagtt cgtcgctcac atgctcctcg
     7681 aatatgtatt cggacatgtg gcgcggagag ccatgatgca cagccaccat cacctcctcc
     7741 accggtcggt gtatggagtt gggtagatct cgtatgtgat cgaaggtgga cgaggagata
     7801 tgctctctgg tccactcgat ggccgccgcg gcgatgctgt tcattccttt ggtgccgacc
     7861 agcaccgccc ggtcgtgatt gccggctatg caatttacgc ccttcctccg taggagatcg
     7921 accacctcgt ccgggtaggt gtaatatccc aggatgtctc cggcgcagta cacctgcgcc
     7981 acgttgcggg cggacatgtc cctgaacacc gcctccaggg cgggaaggtt ggaatgtatg
     8041 tcggaaatga aagcgatctt catcttatca cctcttcata ttctggaaag accgcgacgg
     8101 aggacctgcg gtattctctc caacaggtcg gtggccacca gcccgtagct gttcttctcg
     8161 aatgccagat ctccggccga gccgtttatg aacgccgata tgcgcgaggc attgaagggg
     8221 ttgacgttct tggacagaag cccagcggtc aatccggaaa gcacgtcccc ggttccgccc
     8281 acgctcattc ccgggttgcc ggtccggttc aacttgatcc tctggccgtc agtgatcacg
     8341 tcgatccgtc ccttcagcag caccgtccaa ccggtctcga gcgccaaggt cttggcgcca
     8401 tcaatcctgg aatccaggtc ggaggccacc ggatgcccta gcagcagctc tagctcgcga
     8461 tgatggggag tgagcacgcc ggccttgccc ttcagcagcc caaggtgtcc gctcatcgcc
     8521 ttcagggcgt cggcgtccag gaccatgggt ttggtgcacg agggaacgaa cgagcgcaca
     8581 gcctccaagg tcgccggatc atcccccagc cccggtccca gcagaaccgc atccactcca
     8641 tcggccagtt tttttaactg aggtccgtgc cgcggatcga ggcgggcccc atgcaagcgt
     8701 tcaacgatca gattgggaga ataggaagcc actacatcgc ctacactatc cggacatgct
     8761 acgaacacca gatcggtgcc tatgcgatat gctgacatcc cggccaaggc tggcgctccc
     8821 gtataaggtc cgcctccgat gaccaacagc cttccgttct gtcctttgtg agagtccaga
     8881 gaaggtatcg ggtaatgcac caggtccccc ggtcccacga acctctcggc atctgccggg
     8941 atccctactt cggcgaccac gatctctccg caatgtccct ccgacatgcc ggtcttacgg
     9001 tcgtggaacg tcacggtgag ggtcggtcgg accgccaagg cgctacccat tccggaggga
     9061 acgtctgcgg agacgaccgg ccttcccgag gcgttgatgg ccttcaccag atcggcataa
     9121 ggtcccttcg gcgttccttt ggagcccact cccaacaagg cgtccacgat caggtcgtaa
     9181 ccggagaggt cctctccggc gaacaccttg tggagctcct ccaccttctc gaagttgata
     9241 cgtgactcgg gcgtgcttat ctctgatggc ggcaaggcca ggaacactct gacccggttg
     9301 ctcttggtga gcgcgcgggc ggctaccaga ccatccccgc cattgttccc cttcccgcag
     9361 atgatggcga tgcgcaatcc gcttccgaag cgagaggtga tctcctgggc caaggcccaa
     9421 cccgcgttct ccatcagaac ctccgtggga acccctagga actccgaatt gatgtccagg
     9481 acccggacct cctcccgctc tatcataagg aagtaaatgc tcgagggagt gaataatcct
     9541 ttcctggcaa tcaataacca attaatacca ggattccatt ttaacgctgg tagatattca
     9601 aatgtctgag atcaaacgcc tagtgctcga cgtgctcaaa ccccatcatc cgtcaataat
     9661 cgatctggcc aacaggctca gcgtagtgga aggcgtctcc ggcgtcaact gcaccctgga
     9721 cgaggtggac caggagaccg aaagcatcaa gataaccata gagggcgtgg ccatcaacta
     9781 cgaggacgtt gaagaggtca tcatcgactc cggtgcggta atccactccg tggacagcgt
     9841 ttccgcaggc aagaagctgg tggaagaggt cgagacgcct caggaccgct gagaccttat
     9901 cagcagttct cccacttttt ttaccagcgc ggacttggaa atggtctttt cgaccaaaat
     9961 ccgtccatca ctggagaacc agttggcggg atatttcttt tcccgctcga ccttgtgctg
    10021 cagacccagc tgccggaggg cagccgataa aaggtctacg gtggggtcgt taatggccaa
    10081 gcctttcttg accttgcggc cctgggaccg gggcctcgac cggtcgaaat attccggcca
    10141 gagcacccat gcggtgtctt cgtccagggc catgaaaaac ccgtcggtct tattccttca
    10201 ccaggatggc gttgatggag ccgtcctgtc ctggccggga agttaccttg gccgggccca
    10261 gttcggtctg gatgaccgca cccttggtga ctatgttacg ctgaacgtag ttggggttgg
    10321 ataggcttgt gttgaccttg atgatcttga ccttctgggt cttgttgttg gtcgggtcga
    10381 ccacattggc gaactgagcc ttcaaaaggc gcaccttgac gttcgccccg cgcaccctgg
    10441 acacctggcg cttctcgctg cctacgaagg taaagacagg ctccttaccg atctcgaacc
    10501 tgcgcttact cctagacagt gtcaaacgcc cgccggaggg cttcctctta gacctacctt
    10561 gccataatgc catagcaatc ctgagccacc taattggaca tgtatataaa aaccttggct
    10621 tgtggtctag aggtccagta aggtcagcct gacctcatcc tccagttcca tcatcccggc
    10681 gtagtggtcc ttggccgccc cggggttcat gtaccagatc ccgtccttgc gttccacgcc
    10741 ccggtcctcg tgtatgtgtc ccgacagtac caccgatggc ttacatcggt ctatcgcccc
    10801 ggcgatcgcg gtggagccta catgcaggcc ggagaacgtg gtgtcgaacg ttccgtacgc
    10861 cgggttgtga agcaccagga ccattccctc ctccattatc ggctccagga gccgggagat
    10921 ctcctcctcg ggcatctcga acggagtgcg gaatatgctg gggttcgaac cgccaaggcc
    10981 gccccaggtt cgaccatcga tcgtcatctt gacgccgtgc agggatgttc cggccctctt
    11041 gatgaaagcc tcggtgccca acgggtcaca gtttcctgga acggcatagc acttggtttc
    11101 cagctcggtg atgaggtcct cggcgaactg gggcgggccg aagtgggtga ggtccccgag
    11161 cagcaccact gcgtccaggg aatgctcctt catgagctct ctggccgccg ccgggaccca
    11221 ttcccggcgg tgtacgtcgg ttagcaccag gtatctaccg cccatgggtc gccatatctg
    11281 aaccagggtt aaacattttc ctaggcgaac ccaaagccca ggtcctgata caccagaata
    11341 taggcagtcg cgtaaccaat gatcgcaaat ccgttgagga aggggagccc ggcctgaggg
    11401 cggcctttgg agataaagaa catcagggac aggaatccca agagcaccgc agccagggtc
    11461 agcacgccca cggtcatagc cgggaatggc cagttcgtgg agcttaccgg tgagagattg
    11521 gccgcggcgg agacgatcag caccgaaggg atgatggcat cccccaaccc catcatcatc
    11581 agctctctat cagcgtcctt gctacggtcg tgcaggtcca gtttcttgct ttgcccgccg
    11641 tccttgccgg gaacgatgag cactatcggc agtccgaggt tgcccactcc ctcggccaag
    11701 gtgagcatgt gcttggtgac gtataccgac aaagcgtcat agacggccag cgtcaccaag
    11761 agaatgagcg atggcagaat gcctagcgag aggccgagga ccagtgccgc gcctacgccc
    11821 agcaccaggc cggccccgtt caccacatac cagcggggga acttcaataa aaggagcatc
    11881 agggacccgg ccaggatcgc cccgaaagcc agggaaggta tctcggcgga cccggccagc
    11941 atcgcgaaca acgacccaat ggagaaaagc cccaatccca tagaaatgaa aaggatggcc
    12001 ctcaaaaggc ctaacttgga ccgcttgatc aaaagaagaa gcaccccggt catggccagg
    12061 acgagaacga tgtacattat cggattggtc ggatcgttct ggtccgagaa ggcccggtat
    12121 cccgacggaa ctcccggtat cagcagaagc gccaaggcgg gaacggccag gaacatgccc
    12181 gtcatcacga ggtattgcct ggcgctgcgc atgctaagcc atgcggttcc gctaataaaa
    12241 cgattaggtt agggcgatcc cgggccgggc gctcaagcgg actctatgga cacgtttccg
    12301 taggcgacct ttccagtgat cttggccact ttgaccttta ccctggatcc cttgacggtt
    12361 ccggggacat agatgatgta gtcgaacatc cgggcgaccc cgtcaccctt ctttccgacg
    12421 tcctcgatca tcatctcgta gattccgccc tcgcgcaatc cttcctcgtt gggcttctgg
    12481 accttgcgga cgttgaccgg ccggtgcgca ccgcacgcct cgcactccag gatgagtatg
    12541 cggtcctcct tgttgatgtg ggtgtccggt ctgccgcatt ccgagcacag tacgaaggta
    12601 tcgacatagt tctggatctt gtcggctatc tgggtcgggg tcaggcgggt tttaaatacg
    12661 acccggcgtc cctccatggt gcctggagta ccgagctcgc gcagcatgta ctgcaggatc
    12721 tgctctggct cccggcgcaa ggtgtccacc acgtccccga agttgcggaa cacggtggtc
    12781 ttcccttcct ggaacacatc gggctcgggg accacgaaac gctcgtgctt ctctatggtc
    12841 tccggtaact gcgtcttggc ccggtccaga agggaaaggt aatcgtcatt agccatgtct
    12901 atcggcccat caagtccacc atgccatata aagcttattg ggtcccgccg tatttgcggg
    12961 ccaccgccgc cctgaccaat ccatagtgca ggggcgacgg tttcctgggc cgggacttga
    13021 actctgggtg gaactgtgag gctatgtagt aatcgtaacc ggtcatctcc ccgatctcca
    13081 tcttgacgcc gtcagcggaa cgtccggtga acttccagcc ccccttctcc agctcctcga
    13141 tgtgcttggg gttcacttcg aaccgatggc ggtgcctttc catgatcaga gccttgccat
    13201 agagctcgaa ggccttcgaa ccttcctcga ccatcaccgg ttgggcgcct agcctcatcg
    13261 tcgctcccat cttcttgacg ttcttctgct ccggtaaaag gtccaccacc gggaacgggg
    13321 tgtccggatc gaactctgtg ctgttggccc cttccatccc tagaacgttc ctagcgaact
    13381 cgatggtggc tatctggaat cccagacaaa cgcctaggaa aggtatccgg ttctcccggg
    13441 cgaacttggc ggtggcgatc tttccctcga tgccccgagt accgaatcct cccgggatca
    13501 gtatgccgtc cgctcccaac agctcctcgg ttatgccgta ctgctggacc acctcagaat
    13561 cgacgaaaac gacctggacc ttggtccccg cttccgcccc ggcgtgatgg aaagattcca
    13621 gatgggatat gtaggaatct gccaggttgg tatacttgcc gacacaagct attcttacgg
    13681 ttctctcttg atcgtttatg cggttggcga aggccttcca ctcctcaagc tcctgggtct
    13741 tcgccgtcag gccgaacctc tgcatgacgt agtcggttag gttctgctcc tccagcgcca
    13801 ttggcacgtc gtatatggaa cgggcgtcgg cagcggtgac cacggcctcg atgggaacgt
    13861 cgcagaacag ggatatcttg tgccttatgg actcttccaa aggctccttg caccttgcaa
    13921 cgattatgtc cggctgtatg ccgatggccc tcagttcctt gaccgagtgc tgggtgggtt
    13981 tggtcttctg ctcacccacg gtacccatta ccggcaccag ggtggtatgt acgaacagac
    14041 agttccgtcc cttgcccagg tcctggttca tctggcgaac cgcctccagg aatggcatgg
    14101 actcgatgtc tcccacggta ccgccgagct cgactatgca cacttcggct ccggtcgcct
    14161 cggcgacgtt cacgatgtgc gccttgatct cattggttat gtgcggaatg atctgcacgg
    14221 tctttccgag gtactctccg gtacgctcct tctctatcac cgatttgtag accttgccgg
    14281 tggtgatgtt atgggcgctg gtgagactta tgtccaggaa cctctcatag ttgcctagat
    14341 ccaggtccac ctctccgccg tcatctagga cataaacctc gccgtgctcg aaggggttca
    14401 tggtccccgc atcgacgttc aagtagggat cgatcttaat ggcagtgacc ttgatcccgc
    14461 gggatttcag aagacgacct atggaggaag cggttattcc cttgcccaaa ccagaaatga
    14521 ctccgcccgt gacaaaaatg tatttcatac cttcacggga accttcgata acctaagata
    14581 atatttatga cttacgaccg gagctgctgg atgataacag cgttgaacaa aataaaataa
    14641 aaaattatgc ctagaatggg gacgctcgat gttgttttta gtgcctggta accctgccgg
    14701 aattggtgga ggaaacacac gtaatgccat aagcttcaca gtgtttcccc ttgcgtagga
    14761 ggtgatccat ctgcaggttc ccctacagat accttgttac gacttaaccc tccttgctga
    14821 atctcagttc gaagacccca aaatgagata tccttactga aacccaactc gggtggtttg
    14881 acgggcggtg tgtgcaagga gcaggggcat attcaccgcg gattgttgat ccgcgattac
    14941 tacggaatcc agcttcatga gggtgagtta caaccctcaa tccgaactac gattgggttt
    15001 cgagattgcc ttcacctttc gatgtcggag cccattgtcc caacctttgt agcgcgcgtg
    15061 tagcccagga gattcggggc atacggacct accgttgacc tctccttcct ctgtcttagc
    15121 gacagcggtc ccgttaatgt gcgtgctctc cggagagaac actagcaatt agcggtgagg
    15181 gtctcgttcg ttatctcact taagagaacg ccttacggta cgaactgacg acggccatgc
    15241 accacctctc ggaaaatcag gcaaggtcat cagcctggcc ttcatgtaac cgtcgctcct
    15301 ggtgagttgt ccggtgttga atccaattga accgcacgct cctcccgttg cggtgctccc
    15361 ccgccaattc ctttaagttt catccttgcg gacgtactcc ccaagcagca ggcttaacaa
    15421 cttctctccg gcactgggcg ccctcaaagg acccccaaca ccaagcccgc agcgtttaca
    15481 ccctggacta ccggggtatc taatcccgtt tgcgccccag ggcttcgtcc ctcaccgtcg
    15541 gattcgttct agtgagacgc cttcgccacc ggtggtcctt ctaggattac aggattttac
    15601 ccctacccca gaagtacctc tcacctctcc cgatcccaag tcttgcagtc tccccggact
    15661 tcgaacagtt aagctggtcg atttacccaa ggatttacaa aaccggctac ggacgtttta
    15721 ggctcaataa tatcgaccac cactcgggcc gcgggtatta ccgcggcggc tggcacccgt
    15781 cttacccggc ccttacttct ctggtttttt agaccaaaga acagccaaca caatgtgctg
    15841 gcacttggaa ttccctcatc ggggtttccc ccattgtgaa gttttcgcga ctgctgcgcc
    15901 ccgtagggcc tggactcatg tctcagagtc catctcaggg ctccctctct caaggccctt
    15961 acgcgtcata ggctaggggg tccgttacac ccactacaac ctgatacgcc gcagaccaat
    16021 ccttgggcac cggagttttg gatctaaaag cattccagct ttctagatct atggggtatt
    16081 attctcagtt tcccgaggtt atcccccacc caagggcatg ttatccgcgt gttactgagc
    16141 ggtccgccga gtccttgcga ctctcgactc gcatgtctta atcgaattcc aatagcggtg
    16201 gccgccggca ggatcaaccg gaattgatcc ttcgacaacc atttattaat tgatcgccta
    16261 ggatgtgttt taaagaaaat tggcagagtt accaagtttc accagcagta ccatttcgtt
    16321 agaaacgtta ctgccatcga gcgtcagaaa caagagagca cgtcgacgca ttctcgacgg
    16381 agatcttgtt tctccattcc cattcttttt gcctaccggg atgcaagcat ccagttcggc
    16441 gtttttcacg ctgttgtagc agcgtagaat ccccttaact tcggtctatt atataaccgt
    16501 ttcggggttc tatttttttg aggcgactaa tgcgcctcag acgaagcggt ttcaacgctt
    16561 ccgtccctcc cattatggca gtgctatttc accttttccc ttgatagggc ctcgaaaggg
    16621 cttactgaga gcatcttagg gacgatcaac ctcaagggca caacttgact ttcttatttt
    16681 cttaagaact cgttcatgga ggaacttcgc accaggcgaa tcaggccagc tggaataaat
    16741 agtcagcttt ggcaaaagct attaataacg actcctgctt ttgcagccga aaagcggagg
    16801 tggcccagcc cggcaaggcg atggattgct aatccattgt ccgcaaggac ccgggggttc
    16861 gaatcccccc cttcgcgcca
//
LOCUS       DAOPZI010000030        16206 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_3818_length_16206_cov_10.558356, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000030 DAOPZI010000000
VERSION     DAOPZI010000030.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 16206)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16206)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16206
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3818_length_16206_cov_10.558356"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1095
                     /locus_tag="PKM11_06465"
     CDS             <1..1095
                     /locus_tag="PKM11_06465"
                     /inference="COORDINATES: protein motif:HMM:NF012798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HNX48180.1"
                     /translation="KRGKLASGTPKTKRGIKSSRQNERSRTGHRRGKTMGRYPFVCAY
                     RQYLKNARARLGEGTIEERERKLHFIASIVQDLNGKGRISTSNPHLFTGNDAIEIYLA
                     LKNRKVRGRPPKWSTIRKQTQLLKEVCLEGGNHVIEELLRTGRIRIGCDHREPFSLEQ
                     EELQAIIEACEALGGWKNEVCRFAVAMCTFLQLRPGELQKASVRDLDVRKWTFLVSNP
                     KGKDSYGEVRRLQIPDVLKPFALEYLSTREEMLRSKGIAFAEPLIPAVSCNGAGYYTQ
                     QAFGRLKNDVVKRTGIAFKWKDFRPTGGQLALDGGVSIDQVSLSMRHTSTKTTERYYC
                     RAKADRAFARVNETYNSMFRTEPAIKAEND"
     gene            complement(1132..1207)
                     /locus_tag="PKM11_06470"
     tRNA            complement(1132..1207)
                     /locus_tag="PKM11_06470"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1172..1174),aa:Val,seq:cac)
     gene            complement(1266..1985)
                     /locus_tag="PKM11_06475"
     CDS             complement(1266..1985)
                     /locus_tag="PKM11_06475"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HNX48181.1"
                     /translation="MGMGVERVKTYIHNFDDYIQGGVPKGHVILISGTPGTMKSSVCY
                     SILYNNAKNNGVRSVYMTLEQSKENLLQQMELMGMNDPKVQEMVYVLDLATIRKNVTE
                     MMAKGSWLQVFKMYAETVKKDLGFDLLVLDSLDVLEMAAQLTNDRRNDLFYLFMWLRG
                     MNITSFLIAETPVDNINGGRFEEGYLADGVISLKLQNIGETDVQRRIRAVKLRSTNHK
                     TGYFSLMFSDGMFRATQVINE"
     gene            complement(2044..3357)
                     /locus_tag="PKM11_06480"
     CDS             complement(2044..3357)
                     /locus_tag="PKM11_06480"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HNX48182.1"
                     /translation="MRLPPSKFECPRCGFGVRPGEEQCGRCGEDLKPKASQPVQVNLA
                     SVKLDRDRDGECSTVRIRSIETIQVGRPDSAMQVRTDELNKRERELQERERRLNVKSN
                     EIEERSKEIKEKKEPQPSVDMDEVRRRLREELTRHFEPELEALQAQLDEKEAELQEAR
                     LKLQMLDAGQEMEVVDEAELARITEDIFRELHAQVGASLKVVDTGLLRTHINRLDEVL
                     GGGIPQGHIVLFNGSPGTMKSTLAYTILHRAAVNGTPGLYLSVEQSRRSILRQMERMG
                     MPEADTDGKLRVLDMRELRKEMAAHEGNWRELIMGYVRREQEATGFKVFALDSLESFK
                     ALTEHCFSRQDLKDLFDWFKSLNITVLVISENTSDEYDEADQGEAYLSDGIMEMLMRE
                     MTDSRVQRWVRCVKMRGANVDNRYYSMFHNGKEFNFALPLANQPF"
     gene            complement(3362..4117)
                     /gene="gvpD"
                     /locus_tag="PKM11_06485"
     CDS             complement(3362..4117)
                     /gene="gvpD"
                     /locus_tag="PKM11_06485"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gas vesicle protein GvpD"
                     /protein_id="HNX48183.1"
                     /translation="MEPRKAWWLGVGEMEAGDGRLKTYIEGFDRILEGGIPTGHIVLV
                     AGTPGTMKSSISYYMLYNHAVESGRTSVYVTLEQSRESLLRQMEKMGMDIEKVSENLN
                     VLDLSLIRKKLKEIAGGTSWLHVFKTYITNLKQNLDFDILVIDSMEVLETMAEIRNRR
                     TDLFYLFEWMRDLGVTVFLISESSAERLIEGKFDEGYLSDGIITLKMQLIRDVEMQRR
                     IRCVKMRETNHDPSYYSLLYNGGRFQVTRVISE"
     gene            complement(4154..4858)
                     /locus_tag="PKM11_06490"
     CDS             complement(4154..4858)
                     /locus_tag="PKM11_06490"
                     /inference="COORDINATES: protein motif:HMM:TIGR02495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0051353 - positive regulation of
                     oxidoreductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HNX48184.1"
                     /translation="MIARIVGFAKTSLLDWDGMVATTVYLQGCNLRCPFCHNPDLVAV
                     TGEVEEAPWEVLEEYLADNTDFLDGVVVTGGEPTLNEDLPELIRRIKKLGLKVKLDTN
                     GTNPDMLQDLLQAGLLDCVAMDLKGPLDQQYSQVCDAEVDLEAIKRSINLIMTSGIDY
                     EFRTTVVPHYLKPADIERMASYIGGAKKYALQRFKNDRTLDKRLSQIDPYSEGQMLGM
                     AETARKYVKKVIVRGI"
     gene            complement(4909..5088)
                     /locus_tag="PKM11_06495"
     CDS             complement(4909..5088)
                     /locus_tag="PKM11_06495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48185.1"
                     /translation="MDFSKYKCQFCGRPAKQYVFAAFCCESENCVDQAREERGGPGGH
                     MKAKMHGDIVNIKDE"
     gene            5173..5610
                     /locus_tag="PKM11_06500"
     CDS             5173..5610
                     /locus_tag="PKM11_06500"
                     /inference="COORDINATES: protein motif:HMM:NF024637.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HNX48186.1"
                     /translation="MVFCSRCGSQVPEGAQFCDRCGASLGGGFQSYGQGNQTTMPYTY
                     RKDEKEIILAVILSLIIPGVGQIYCGRIGRGIGILVISGLFGLVSFIPLLFIFDPASF
                     NFAGFFALMVVVSIIALIFYIWQIYDAYRCADDYNRQAPPMRY"
     gene            complement(5611..6426)
                     /gene="nadC"
                     /locus_tag="PKM11_06505"
     CDS             complement(5611..6426)
                     /gene="nadC"
                     /locus_tag="PKM11_06505"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: protein motif:HMM:TIGR00078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0019363 - pyridine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HNX48187.1"
                     /translation="MDLIDLYLQEDLGQGDVTSQALVDDRDGRAVITAGQGGVLAGIE
                     EAVEVFRRLGCSCQVLTNDGEEVTSGQKVLEVSGSLKGLLAGERLALNFLMRMSGIAT
                     LTRQVVESCRKANPNLVIAATRKTTPGFRRYEKKAVRIGGGDPHRFGLDDAFLIKDNH
                     LTVVGSVFKAVRRARSFSFGKKVEIEVEDLDAAKEAARAGADIVMLDNMTPAQAKECY
                     LAIKGIDQRITVEVSGGITPQSAKSYAQYADVISMGALTHSAQAMQLSMHILE"
     gene            complement(6464..7711)
                     /locus_tag="PKM11_06510"
     CDS             complement(6464..7711)
                     /locus_tag="PKM11_06510"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX48188.1"
                     /translation="MKIKFLGGADLVGKLGMLVQNQGANIMFEYGMRLVKPEMPHFPL
                     MPEENVDGVFITHAHLDHSGAVPLLVQQKDCEVICNELTMDIANLLFFDSIKIAKSEG
                     FTTFPYKDTDIKHAWQNYSPFYIGETRSIAGLEILAHNAGHIPGAQMYEIKGHNTSLF
                     TGDLHTENTRLTYGAKPVKCDNLIIEATYAGRNHPPRPKSEALLQQRVREVVERGGTA
                     IIPCFAVGRMQEVMMILKDLPYDMWVDGMGKTVNSMYTDHQEHPYLRSMRDFKAAKRK
                     FNPVRTSSAREKARQGQVIITTSGMLDGGPVLHYLKDQKDNVKSAVMMVGYQAENSNG
                     RMLKEKGRVETIQDGIIDIKCEVMTFDLSAHADHDQLLSFIKGCQPEKVVLMHSDNRA
                     ELAQDLEGDYEVLMPMPGNNFEL"
     gene            7940..8296
                     /locus_tag="PKM11_06515"
     CDS             7940..8296
                     /locus_tag="PKM11_06515"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48189.1"
                     /translation="MGEFAISYRTKGPLDGDRVWLSSGFRVQLIKMGIEKAGSVNELG
                     RRMGYRSRVHPGWGVVQIMQGKQAFPVSRLKLLADYLEYPYHDILQYVTPPNRVTLES
                     TKSALAMYGLGGYIPR"
     gene            8387..9295
                     /locus_tag="PKM11_06520"
     CDS             8387..9295
                     /locus_tag="PKM11_06520"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48190.1"
                     /translation="MVFRRSADADDEITNTLIDRGVYRLSEVYEDEEIKKFKDLKAPY
                     SFWSAVKYSLILTVLLWWLPVFGQMVAGFVSGRRAGKPWKGVVAALVPLTIVFILSLL
                     VDNGIIPSVINGVDWTPSHILEMAKDMIPLLAPYILFVEMYLTAFIDTIQIATDLRVD
                     VYIITAAFAYIGGILAEQSRLEMNYVAKHGGNSMTVMVGGGEKAAKEEVAEERPARGK
                     RPVSAKQVKTRQAQKVIRFGDLKDLTTASDEDYVQEYTERGEQWYEEGEEPDEDVPKN
                     IAGLAKRSSPGSEKGKKPKPGDWKFI"
     gene            9352..9657
                     /locus_tag="PKM11_06525"
     CDS             9352..9657
                     /locus_tag="PKM11_06525"
                     /inference="COORDINATES: protein motif:HMM:TIGR01384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor S"
                     /protein_id="HNX48191.1"
                     /translation="MFCPKCRRIMKPDKGKFVCRNPDCKHEVVEDIKPFCFTTCGKEK
                     EMTIIDGNAPTLPRTRIDCPKCGHQEAFWVLRQTRAADEPETKIYRCVSCGHSWREY"
     gene            9724..10461
                     /gene="pcn"
                     /locus_tag="PKM11_06530"
     CDS             9724..10461
                     /gene="pcn"
                     /locus_tag="PKM11_06530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030337 - DNA polymerase processivity
                     factor activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proliferating cell nuclear antigen (pcna)"
                     /protein_id="HNX48192.1"
                     /translation="MFQAKLRSDILKGIVDVVSTLIDEAKFKIGENGIQLKAVDPAHV
                     AMIDLTLGKDAFEQYSAAETDLGLDLEKLKEVIRLSKSGDLIEMRQDEERGRLVLMVG
                     NVTRRMNLVSTEGMSDPKVPNLTLPARITVTVDELQRGIKAAESISDHVALNANTEGF
                     EMVSDGDTDSVSLKLPKALLVDLQCSESIRSLFPMDYFSTIIKAIPSGTNVSVNLGND
                     LPVRLDFDIAGGKGSVRYLLAPRIEND"
     gene            complement(10458..11228)
                     /locus_tag="PKM11_06535"
     CDS             complement(10458..11228)
                     /locus_tag="PKM11_06535"
                     /inference="COORDINATES: protein motif:HMM:NF014069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HNX48193.1"
                     /translation="MAFEVPVQGNARLSTLLDRINSDEEVKALWKASNINAIDRLGFS
                     DHGSTHVRIVARNALRMLRLLMEAGHQPGVVKNYGLTKEDAEVVVVLASAMHDIGLSI
                     HREDHDHFSIMISPPILRRMLLGLYEEPTLTYIVAETQHAMISHHEGFVPYTIEGGVV
                     RVADALDMEKGRARIPFASGSINIHSVSALAIDKVRVGKGAERPIQIDILMNNSAGIF
                     QVDELLKEKIARSGLRELITVEVKMPEAESGIVKGLRL"
     gene            11356..12192
                     /locus_tag="PKM11_06540"
     CDS             11356..12192
                     /locus_tag="PKM11_06540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HNX48194.1"
                     /translation="MKSINEGRVKELEQKAASLRRHVVKMIYAAGSGHPGGSLSATDI
                     MTALFFEVMDHSPERMGSQDRDHFIMSKGHAAPIYYAALAESGYFPVEELVTLRKLHS
                     RLQGHPSRVKTPGVEMSTGSLGQGLSVANGLALALRLQNLDRKVYCLCGDGEMAEGQI
                     WEAAMFAAHYHLENLIAIVDRNGLQIDGRTEDVMALEPLADKWKAFGWNVLFMDGNDM
                     WQVLETLNEARQHKGGPTVIVAKTVKGKGVSFMENNVGFHGKSPNEKEYEQAMRELGG
                     SA"
     gene            12189..13133
                     /locus_tag="PKM11_06545"
     CDS             12189..13133
                     /locus_tag="PKM11_06545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HNX48195.1"
                     /translation="MSWALESQRKNYGKALVELGKRRKDIVVLDADLSGSTRTVEFKT
                     AYPDRFFNCGIAEQNMMGTAAGLAVCGMTVFASTFAVFATGRAYDQIRQSIAYPNLNV
                     KVVASHAGITVGGDGASHQTMEDIALMNAIPNMTVIVPADGPETYNAVLAAAEHRGPV
                     YIRMGRSEVPVITPREAAFKIGKATTLREGSDVALVGVGQMVAPCLLAADALKAKGIN
                     ARVINLSTIKPLDVGTLERAARECGCVVTAEEHNIVSGVGTLVAAVLAERHPTPMERV
                     AMQDVFGQSGESDELMKEYGLSEKEVIAAAIRVMERKK"
     gene            13130..13777
                     /gene="fsa"
                     /locus_tag="PKM11_06550"
     CDS             13130..13777
                     /gene="fsa"
                     /locus_tag="PKM11_06550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HNX48196.1"
                     /translation="MKIFIDTANIEQIKEVSSWGILDGVTTNPSLIAKEKKDFATIVN
                     EICEVVDGPISVEVISLKADGMFAEGMKLAAVNENIVVKVPMTEEGLKATKLLSNEGV
                     AVNMTLIFSANQALLAAKAGARYVSPFVGRLDDVGQDGMALISDIMDILDNYDFDTEV
                     IVASVRDPIHVTDAARMGAHVATIPFDVLKKMFKHPLTDIGIERFLKDWEKVSKP"
     gene            13857..15014
                     /locus_tag="PKM11_06555"
     CDS             13857..15014
                     /locus_tag="PKM11_06555"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF017634.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HNX48197.1"
                     /translation="MKCDVLVVGGGPTGCLAAASMAGELDVKVLEEHPGVGEPVQCAG
                     LVTPRVVEMASASDTVLNTIDGAYVHFPGGRVIELQGNSVKAVVVDRGEFDRRCASLA
                     TRNGAQVLTGRKVASVERTKSGMNAHTPEEEVECEALLAADGYRSGVARSLGFAAAKD
                     MVRGLEVDLRLKAEDQRKVRVFLGNEVAPGFFAWAIPCGDLTRVGLCVSRDRGTPQEF
                     LTRLLEAQGWGEAERVRTYSGAIPLGHIPRTYADRVLVAGDAAGMAKPISGGGLFTGM
                     TAGRLAAETFLEAFRSNDLSETNLSKYEQRWKAVYGSELRSSYRVRKVFVRMSDRDLD
                     KAGARLDNEKAKNVLATGDIDFPTALAPGLLKACPSLLTIAPLLIFRLLWR"
     gene            15018..16022
                     /locus_tag="PKM11_06560"
     CDS             15018..16022
                     /locus_tag="PKM11_06560"
                     /inference="COORDINATES: protein motif:HMM:NF014527.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase family
                     protein"
                     /protein_id="HNX48198.1"
                     /translation="MRALSVPKSEADGVKDKLNRRRQLDLEWRPGRAGEMVLLPLIGD
                     NPFPEYPVVDAELQPQDRHRPPQERIAEILMLPKELNALLPDKYERLGHVIVLRLPDQ
                     LLPYRQEIAAAYALVLKAKTVLLEKGIIRGVERRPDMELLFGTETETTHSESGILYRL
                     DPTKVMFSSGNFDEKLRMASLDCRGETVVDMFAGIGYFTMPLAAKARAEQVIACEINP
                     DAIGFLKKNIELNQVADRVTVFEGDNRQLPGEGFADRVVMGYVNVTWQFLPKAFSMVK
                     RGGIIHYQDTCSIDRIPDGLIENLRKGSGGRPFEVLGIKEVKAYAPSISHMVLDVRAL
                     "
     gene            complement(16009..>16206)
                     /locus_tag="PKM11_06565"
     CDS             complement(16009..>16206)
                     /locus_tag="PKM11_06565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48199.1"
                     /translation="CYAFLEAVGEAQQRKWQFTKEERESGEHFAPYARELLRTEREEY
                     HCALLRLLQESGSSETVVRAP"
BASE COUNT         3274 a         4762 c         4863 g         3307 t
ORIGIN      
        1 aagcgcggaa aactcgcctc gggaacgcct aagacgaaaa gaggaataaa atcctcccgg
       61 cagaacgagc gttcccggac agggcacagg agagggaaga caatgggtcg atatcccttc
      121 gtgtgtgcct atcgacaata cctgaagaac gcccgtgccc gtctcgggga aggtacgata
      181 gaggagaggg agcgcaaact gcatttcatc gcctcgatcg tgcaggacct caatggcaag
      241 ggcaggataa gcacctcgaa cccccatctg ttcacaggga acgacgccat cgaaatatat
      301 ctggcattga agaacaggaa ggtgagggga aggccgccca aatggtcaac catccgtaag
      361 cagacgcaac tgctgaagga ggtatgtctg gagggaggca atcacgtcat cgaagagctg
      421 ctgaggaccg gacgtatccg catagggtgc gaccaccggg agccgttctc cctggagcag
      481 gaggagctgc aggcgataat cgaagcctgc gaggcgctcg gaggttggaa gaatgaggtg
      541 tgccgctttg cggtcgccat gtgcaccttc ctccaactgc gcccggggga gctgcagaag
      601 gcgtccgtgc gggacctaga cgtgaggaag tggaccttcc tcgtgtccaa tcccaaaggc
      661 aaggattcat acggcgaagt tcgccgcctg cagataccgg acgtcctgaa gcccttcgcg
      721 ctcgaatatc tcagtacgag ggaagagatg ctcaggtcca aggggatcgc gttcgcggaa
      781 ccgctgatac cggcagtttc ctgcaatggc gcaggctact acactcagca agctttcggg
      841 cggttgaaga acgacgtggt gaagcgtacg ggcatcgcct tcaagtggaa ggacttccgg
      901 cctactggag ggcagctggc attggacggc ggcgtttcta tagatcaggt atcgttgagc
      961 atgaggcaca catcgacgaa gacgacggag cggtactatt gccgcgccaa ggctgaccgt
     1021 gcgttcgccc gggtcaatga aacatacaac agcatgtttc ggaccgagcc agctataaag
     1081 gctgaaaacg attgaattga attcaaaaaa taattgtctg gatataagta gtggtgggct
     1141 cagccggatt cgaaccggcg accttctgcg tgtgaagcag acgtcataac cgctagacca
     1201 tgagcccttc ggtaggcgat gcaaatggga acgggatata aaaatgttta gcggatgacc
     1261 agccatcatt cgttgatgac ctgggtggcc cggaacatgc cgtcgctgaa catgagcgaa
     1321 aagtagccgg tcttgtggtt ggtggaacgc aatttcacgg cgcggatacg acgctgcacg
     1381 tcggtctccc cgatgttctg cagcttcagg gagatcacgc cgtcggccaa atagccctcc
     1441 tcgaaacgac cgccgttgat gttgtccacc ggcgtctcgg cgatgaggaa cgaggtgatg
     1501 ttcatacccc tcagccacat gaaaaggtag aacaggtcgt tacgtcggtc gttggtcagc
     1561 tgggcggcca tctccagcac gtccagggaa tcgagcacca gaaggtcgaa ccccaagtcc
     1621 ttcttgaccg tctcggcgta catcttgaag acctgaagcc aggaaccttt ggccatcatc
     1681 tcggtgacgt tcttcctaat cgtcgccagg tccagaacgt agaccatctc ctgcaccttc
     1741 gggtcgttca tgcccatcag ctccatctgc tgcaggaggt tctccttgct ctgctccaag
     1801 gtcatgtaga cgctgcgtac gccgttgttc ttggcgttgt tgtacaggat gctgtagcat
     1861 accgacgact tcatcgtgcc aggcgtacca gatatcagaa ttacgtgacc cttcggcact
     1921 ccaccttgga tgtaatcatc gaagttgtgg atgtaggtct tcacccgttc tacgcccatg
     1981 cccattcact cggggattta tggatatacc aggtatataa taccgtattt aaaatttaat
     2041 tttttagaaa ggttggttgg ccaggggcag agcgaaattg aactccttcc cgttgtggaa
     2101 catgctgtaa tagcggttgt cgacgttggc cccgcgcatc ttcacgcaac gcacccaacg
     2161 ctgcacccgg gagtcggtca tctcccgcat gagcatctcc atgatcccgt cggaaagata
     2221 tgcctcgccc tggtcggcct cgtcatactc gtccgaggta ttctcggaga taaccagcac
     2281 ggttatgttc agggatttga accagtcgaa gaggtccttg aggtcctgac gggagaagca
     2341 gtgctccgtc agcgccttga acgattccag ggagtccagg gcgaacacct tgaaaccggt
     2401 ggcctcctgc tcccggcgca catagcccat gatcagttcg cgccagttgc cttcgtgcgc
     2461 cgccatctcc ttgcgcagtt cgcgcatgtc cagtaccctg agctttccgt ctgtgtccgc
     2521 ctcgggcatg cccatgcgct ccatctgcct caggatcgat ctacggctct gctccacgga
     2581 caggtacagt ccaggagttc cgttcaccgc cgcccggtgc aatatcgtgt aggctagggt
     2641 gctcttcatc gtacctggcg agccgttgaa cagtactatg tgcccttgcg gtatgccgcc
     2701 gccgagcacc tcgtccagac ggttgatgtg cgtgcgcagc agaccggtat ccacgacctt
     2761 cagggaagcc ccgacctggg cgtgcagttc gcggaatatg tcctcggtga tgcgggccag
     2821 ctcagcctcg tccaccactt ccatctcctg tccggcgtcc agcatctgca atttcaatcg
     2881 agcttcctgc agctccgcct ccttctcgtc cagctgcgcc tgcagcgcct ccagctccgg
     2941 ttcgaagtga cgggtgagct cttccctgag ccggcggcgc acctcatcca tgtccacgct
     3001 cggctggggc tcctttttct ctttgatctc cttagagcgt tcctcgatct cgttggattt
     3061 gacgttcagg cgtcgctcgc gctcctgaag ctccctctcc cgcttgttca gttcgtccgt
     3121 ccggacctgc atggcgctgt ccggccggcc cacctggatg gtctcgatgg aacgaattcg
     3181 caccgtcgag cattcaccgt ccctatcgcg gtccagcttg accgaggcca ggttgacctg
     3241 caccggctgg ctggccttgg gcttgaggtc ctcgccgcaa cggccgcact gttcctcccc
     3301 cggccgcacg ccgaagccgc agcggggaca ctcgaactta ctgggcggga ggcgcatcag
     3361 atcactcgct tatcaccctg gtgacctgga agcggccgcc gttgtacagc aacgaatagt
     3421 aggagggatc gtggttggtc tccctcatct tgacgcacct gatgcggcgc tgcatctcca
     3481 cgtcgcggat cagctgcatc ttcaaggtga tgataccgtc cgaaagataa ccttcatcga
     3541 acttcccctc gatcaaacgc tcggcggaac tttcggagat gaggaatacc gtgactccca
     3601 ggtcccgcat ccactcgaaa aggtagaaca ggtccgtgcg gcggttccgg atctcggcca
     3661 tggtctccag gacctccatg gaatcaatga ccaggatgtc gaagtccagg ttctgcttga
     3721 ggttggttat gtaggtcttg aacacatgta gccaggacgt gccgccggcg atctccttga
     3781 gcttctttcg gatcaaggag aggtccagga cgttcaggtt ctcgctgacc ttctcgatgt
     3841 ccatgcccat cttctccatc tggcgcagca ggctttcccg gctctgctca agagttacgt
     3901 aaacggaggt ccggccggac tccacggcgt gattgtagag catgtagtaa cttatggacg
     3961 acttcatagt ccccggggtg ccggccacca gcactatgtg cccggtcggt atccctcctt
     4021 ccagaatcct gtcgaaaccc tcgatgtacg tctttaaccg gccgtctccc gcttccatct
     4081 ccccgacccc cagccaccag gcctttcggg gttccatgcg tttacaggct aataaaggac
     4141 tcgtcgacgg ttatcagatg ccgcggacga tgaccttctt gacgtacttc cgagcggtct
     4201 ccgccatgcc cagcatctgc ccctcagagt aggggtcgat ctgactgaga cgcttgtcca
     4261 gcgtgcggtc gttcttgaat ctctgcaggg cgtacttctt ggccccgccg atgtaggacg
     4321 ccatgcgctc gatgtcggcc ggtttcagat agtgcgggac taccgtggtc cggaactcgt
     4381 agtcgatgcc ggaggtcatg atgaggttaa tggagcgctt gatggcctcc aggtccacct
     4441 cggcatcgca tacctgggaa tattgctggt ccagaggccc cttgaggtcc atcgccacac
     4501 agtccagcag accggcctgc agaaggtcct gcaacatatc cgggttggtg ccgttggtgt
     4561 ccagcttgac cttgagaccc agcttcttga tccttctgat cagttcggga aggtcctcgt
     4621 tcaacgtggg ctctcctccg gtgacgacca ccccgtccaa aaaatcggta ttgtccgcca
     4681 gatattcctc caggacctcc cagggagctt cctccacttc cccggtgacg gcgaccaggt
     4741 cgggattatg acagaacggg cagcgcaggt tgcagccttg caggtagacg gtggtagcga
     4801 ccattccgtc ccaatcgaga agcgaggtct tggcgaatcc gactattctg gcgatcatga
     4861 tcggctggaa taattccagg tggtttttaa gggtatctct aaaaaccttc attcgtcctt
     4921 gatgttcacg atgtcgccgt gcatcttggc cttcatgtgg ccgcccggac cgcccctctc
     4981 ttcgcgggcc tggtccacgc agttctcgct ctcgcaacag aaggcggcga acacgtactg
     5041 cttggccggc cggccgcaga actggcactt gtacttagag aagtccatgg tgcgtccacc
     5101 gtcccctatc gataaagctc tttcgaaatt ttcttaagtt agtaaaaaaa tgatcgttcc
     5161 ggggaagttg agatggtttt ctgttcaaga tgcggaagcc aggttccgga gggcgctcag
     5221 ttctgcgacc gttgcggcgc atccttgggg ggcggtttcc agagctatgg ccaaggcaat
     5281 cagaccacga tgccctacac ctaccggaag gacgagaagg agatcatact ggccgttatc
     5341 ctttctttga taattccggg agtgggacag atatattgcg gaaggatcgg ccgggggatt
     5401 gggatattgg ttatttccgg cctgttcgga ttggtgtcgt tcatcccgct gttgttcatc
     5461 ttcgacccgg cgagcttcaa tttcgcagga ttcttcgccc tgatggtggt ggtcagcata
     5521 atcgccttga tcttctacat ctggcagatc tatgacgcct atcgctgcgc cgatgactat
     5581 aacagacagg cgccgccgat gaggtactga tcattccagg atgtgcatgg acagttgcat
     5641 cgcctgagcg gagtgggtga gcgcgcccat ggagatcacg tccgcgtatt gggcgtagct
     5701 cttggcgctc tggggagtga tgccgccaga cacctccacg gtgatgcgct ggtctatacc
     5761 cttaatcgcc agataacact ccttggcctg ggctggcgtc atgttgtcca gcatgacgat
     5821 gtccgctccg gccctggctg cctccttggc cgcatccagg tcctccacct cgatctccac
     5881 cttctttccg aaggagaagg atcgcgccct gcgcacggcc ttgaagacgc tgccgaccac
     5941 ggtcagatga ttgtccttga tcaggaacgc gtcgtccagt ccgaaacggt gcgggtcccc
     6001 tccgccgatc ctgacggcct tcttctcata gcggcggaag ccaggagtgg tcttgcgggt
     6061 ggcggcgatg accaggttcg ggttggcctt gcggcaggac tcgacgacct ggcgggtgag
     6121 ggtggcgata ccgctcatgc gcatcaaaaa gttcagggcc agacgttcac cggccagcaa
     6181 tcccttcagg gaaccgctta cctccaggac cttctgtcca gaggtgacct cctcaccatc
     6241 gttcgtcagg acctggcagg agcaccccag gcggcggaag acctccacgg cctcctcgat
     6301 gccggcaagg acgccgccct gcccggcggt gatgaccgcc cggccgtccc ggtcgtcgac
     6361 caaggcctgg gaggtgacgt ccccctgccc caggtcctcc tgcagatata gatcgatgag
     6421 gtccatgctg gtcaatcacc gtctggtctt atgaaggatg ccctcagagc tcgaagttgt
     6481 tcccgggcat gggcatcagg acctcgtagt cgccctccag gtcctgggcc agctccgcgc
     6541 ggttgtcgga gtgcatgagc acgaccttct ccggctggca gcctttgatg aagctcagca
     6601 gctggtcgtg gtcggcgtgg gcggaaaggt cgaaggtcat gacctcgcac ttgatgtcga
     6661 tgatcccgtc ctggatggtc tcgacccttc ccttctcctt gagcatgcga ccgttcgagt
     6721 tctcggcctg atagccgacc atcatgaccg cgctcttgac gttgtccttc tggtccttca
     6781 ggtaatgcag gaccgggccg ccgtccaaca taccggaggt ggtgatgatg acctgcccct
     6841 ggcgggcctt ttcgcgagcg gacgacgtcc gtaccgggtt gaacttgcgc ttggcggcct
     6901 tgaaatccct catgctgcgg aggtagggat gctcctggtg atcggtgtac atgctgttca
     6961 ccgtcttgcc catcccatcc acccacatgt cataggggag gtccttgagt atcatcatta
     7021 cctcctgcat tcgccccacg gcgaaacagg ggattatggc ggtcccgccg cgttccacga
     7081 cctcccgcac cctctgctga agcagcgcct cgctcttcgg ccgcggggga tggttcctac
     7141 cggcgtaggt ggcctcgatg atcagattat cgcacttcac cggcttggcc ccataggtca
     7201 gccgggtgtt ctcggtgtgc aggtctccgg tgaagagcga ggtgttgtga cccttgatct
     7261 cgtacatctg cgccccgggg atatgcccgg cgttatgcgc cagtatctcc agtccagcta
     7321 tggaacgggt ctccccgatg tagaacggag agtagttctg ccaggcatgc ttgatgtccg
     7381 tgtctttgta agggaaggtg gtgaaacctt cggacttggc gatcttaatg gagtcgaaga
     7441 acagcaggtt cgcgatgtcc atggtcagct cgttgcagat gacctcacaa tccttctgct
     7501 gcaccagcag aggtaccgct ccgctgtggt cgaggtgggc gtgggtgatg aacaccccgt
     7561 ccacattctc ttccggcatt agggggaagt ggggcatctc cggtttgacc agacgcattc
     7621 cgtattcgaa cattatattg gcgccttggt tctgcacaag cattcccagc ttgccgacca
     7681 ggtcggcgcc gcctaagaat ttgatcttca tttttctgac ctcttatatt tgtgatatat
     7741 ggatagtgat cgttcacccg cttgccgtac ggtcctgtcc cgcccttgtt cgcggacacc
     7801 gtgcagcaac ggaacgttgc aatatgctcg ttcaggctac tccaaatgcg tataaactat
     7861 ttttggtcgg gcagacccgt ctgagatgtc ggaaacgacg aactcaaatc ttttatacct
     7921 aggtgtgcga tgaattgtca tgggcgagtt cgccatcagc taccggacga aaggacctct
     7981 agacggcgac cgggtgtggc tgagctcggg cttccgggtc cagctgatca agatgggcat
     8041 cgagaaggcc ggttccgtga atgagctggg acgaaggatg gggtaccgat cgcgcgtcca
     8101 tccaggatgg ggcgtggtgc agatcatgca ggggaagcag gccttcccgg tatcccgatt
     8161 gaagctcctg gccgactatc tggagtatcc ttaccacgat atccttcagt acgttacccc
     8221 acctaaccgg gtgaccctgg agagcaccaa gagcgccttg gccatgtacg gcctcggcgg
     8281 gtacatccct aggtgatgct ggcactcggc cgacgcggaa aaagtgattt atagtaaccg
     8341 tgtcatattg taattgtcgg acacatgtcc gaccgaaggg gatgggatgg tattcaggcg
     8401 tagcgccgat gcggacgatg agataactaa cacgctcatt gaccgcgggg tctaccgcct
     8461 ctccgaggtc tatgaggacg aggagatcaa gaagttcaag gacctcaagg ccccctattc
     8521 gttctggagc gcggtgaagt actccttgat tctgaccgtt ctcctgtggt ggctcccggt
     8581 cttcggtcag atggtggccg gtttcgttag cggccgccgc gccggaaagc cctggaaggg
     8641 agtggtggcc gcgctggtcc cccttacgat agtgttcatc ctatcgctgc tggtagacaa
     8701 cggtatcata ccctcggtca tcaacggcgt ggattggacg ccctctcata tcctagagat
     8761 ggcgaaggac atgatcccgc tcctggcccc gtacatattg ttcgtcgaga tgtacctcac
     8821 ggcgttcatt gacaccatac agatcgccac cgacctccgg gtggacgtgt acatcatcac
     8881 cgccgccttc gcctacatcg gcgggatctt ggccgaacag tccaggttgg aaatgaacta
     8941 tgtggccaag cacggcggta actccatgac cgtgatggtc ggcggagggg aaaaggcggc
     9001 caaggaagaa gtggcggagg agaggccggc ccgtggaaaa cgcccggtct ccgccaagca
     9061 ggtcaagacc aggcaggcgc agaaggtcat acgcttcgga gatctgaagg acctcaccac
     9121 cgctagcgac gaggattacg ttcaggagta caccgagcgc ggggagcagt ggtacgagga
     9181 gggcgaggag cccgatgagg acgtgccgaa gaacatcgcc ggcttggcca agaggtcctc
     9241 cccggggtcc gaaaaaggca agaaacctaa gccaggcgat tggaagttca tctaggtccg
     9301 ctgaataatt ttttataggc ctatcttttg tggtgctttg gcgagtgtct aatgttctgt
     9361 cccaaatgcc gcaggatcat gaagccggac aaagggaaat tcgtttgcag gaatccagat
     9421 tgcaagcacg aggtggtcga ggacatcaaa ccgttctgct ttaccacctg cgggaaggaa
     9481 aaggagatga ccataatcga tggcaacgcc cctacccttc cccgcaccag gatcgactgc
     9541 cccaagtgcg ggcaccagga agctttctgg gtgctgcgcc agaccagggc cgccgatgag
     9601 ccggagacca agatataccg ttgcgtctcc tgcgggcact cctggcgaga gtactgaata
     9661 agccttcgat ttgcagaaaa gttataatta gatagggctt tactgtggaa agaaggggac
     9721 ccgatgtttc aggctaaatt aagatccgac attctgaaag ggatcgtcga cgtcgtttcc
     9781 acgctcattg acgaggccaa gttcaagata ggcgagaacg gcatccagct caaggcggtc
     9841 gacccggccc acgtggccat gatcgacctg accctgggca aggacgcctt cgagcagtac
     9901 tccgccgccg agaccgacct cggtctggac ctggagaagc tgaaggaggt cattcgacta
     9961 tccaagtccg gcgacctcat cgagatgcgt caggacgagg aacgcggccg tctggtgctc
    10021 atggtcggca acgtcacccg ccgcatgaac ctggtatcca ccgaaggaat gagcgacccc
    10081 aaggtcccca atctgacgct tcccgcccgc atcaccgtca ccgtggacga actgcagcgg
    10141 ggcatcaagg ccgcggagag catatccgac cacgtggcgc tcaacgccaa caccgagggt
    10201 ttcgagatgg tctccgatgg tgacaccgat tccgtcagcc tgaagctgcc caaggccttg
    10261 ctggtggacc tgcagtgctc ggagagcatt cgctccctgt tccccatgga ctacttctcg
    10321 accatcataa aggccatacc cagcggcacc aacgtcagcg tgaacctggg caacgacctg
    10381 ccggtacgcc tggacttcga catcgccggc ggcaagggca gcgtccgcta cctgctggcc
    10441 ccgcgcatcg agaacgatta gaggcgcaaa cccttcacga tcccgctttc cgcctcgggc
    10501 atcttcacct ctacggtgat gagctcccgt agaccggagc gggcgatctt ctcctttaaa
    10561 agctcgtcca cctggaatat cccggccgag ttgttcatca gaatgtctat ctggatcggc
    10621 ctttccgccc cctttcccac ccggaccttg tcgatggcca gagcgctcac cgagtgaatg
    10681 ttgatgctac cgctggcgaa cggtatgcga gcccttccct tctccatgtc cagagcgtcg
    10741 gccacccgga ccacgccccc ttcgatggtg taaggcacga agccctcatg atgggagatc
    10801 atggcgtgct gcgtctcggc cacgatatag gtgagcgtcg gctcctcgta gaggccgagc
    10861 agcatgcgcc ggagtatcgg cggggagatc attatggaga aatggtcatg gtcctcgcgg
    10921 tggatcgaga gacctatatc gtgcatcgcg gaggccagaa cgaccaccac ctcggcgtcc
    10981 tccttggtca gcccatagtt cttcaccaca cctggctgat gcccggcctc catcagcagg
    11041 cggagcattc gaagggcgtt gcgggccact atgcgcacgt gcgtggagcc gtggtcgctg
    11101 aaacccaggc ggtctatggc gtttatgttg gacgccttcc agagggcctt gacctcctcg
    11161 tcggagttga tgcggtccaa caacgtggac aatcttgcat tgccctggac gggcacctcg
    11221 aacgccatac gagggagatg tccttgtcaa tagattaaac cttgattgtt cggtggtacc
    11281 gctgttttga catttggaaa atatttttaa gtgatggccc tataatgacc acaccccatc
    11341 cctaggtgct ttactttgaa atccataaat gaaggacgtg ttaaggagct ggaacagaaa
    11401 gctgcttccc tgcgcaggca cgtcgttaaa atgatctacg ccgccggttc aggacacccg
    11461 ggcggttcgc tctccgccac ggacatcatg accgcccttt tcttcgaggt catggaccac
    11521 tccccggagc gcatgggctc ccaggaccgg gaccatttca taatgtccaa ggggcacgcc
    11581 gcccctatct attacgctgc tctggccgaa tctggctact tcccggtgga agaactggtc
    11641 accttgcgca agctgcattc ccgcttgcaa ggccacccct cccgggtgaa gacccccggc
    11701 gtggagatgt ccacgggatc gctgggacaa gggctctccg tcgctaacgg cctggccctg
    11761 gccctgcgcc ttcagaacct ggaccgcaag gtgtactgcc tgtgcgggga cggggaaatg
    11821 gccgagggcc agatctggga ggcggccatg ttcgccgccc actatcacct ggagaacctc
    11881 atcgccatcg tcgaccgcaa cggcctgcag atagacggcc ggacggagga cgtgatggcc
    11941 ctggagccgt tggccgacaa gtggaaggcc ttcggctgga acgtgctgtt catggacgga
    12001 aacgatatgt ggcaggtgct ggagaccttg aacgaggcgc gccagcacaa gggaggcccg
    12061 acggtcatcg tggccaagac cgtgaagggg aagggcgttt ccttcatgga gaacaacgtg
    12121 ggcttccacg gcaagtcgcc gaacgagaag gagtatgagc aggccatgcg cgagctgggg
    12181 ggatcggcat gagctgggcc ctggaatcgc agcgcaagaa ctacggtaag gcgttggtcg
    12241 agctcggtaa gcgccggaag gacatagtgg tcctggacgc cgacctatcc ggttcgaccc
    12301 gtaccgtgga gttcaagacc gcctacccgg accgattctt caactgcggt atcgccgaac
    12361 agaacatgat gggcaccgcg gccggactgg cggtctgcgg tatgaccgtg ttcgcctcga
    12421 cgttcgcggt gttcgcgacc ggacgagcgt acgatcagat acggcagtcc atagcttatc
    12481 ctaacctcaa cgtaaaggtc gtagcctcgc acgccggcat caccgtcggc ggagatggcg
    12541 cttcccatca gaccatggag gacatcgccc tgatgaacgc catacccaac atgaccgtca
    12601 tcgtcccggc ggacgggccg gagacctaca atgccgtgct ggcggcggcc gagcaccgcg
    12661 gtccggtcta catacggatg ggccggagcg aggttccggt catcactccc agggaggccg
    12721 cgttcaagat cgggaaggct accacccttc gtgaggggtc cgacgtggcg ctggtcggcg
    12781 tgggacagat ggtagccccc tgcctgctgg ccgcggacgc gctcaaggcg aagggcatca
    12841 atgcccgggt gatcaatctt agcaccatca agcccttgga cgttggtacg cttgaaagag
    12901 cggccaggga atgcggatgc gtcgtgaccg ccgaggagca caacatagtc tccggcgtcg
    12961 gcactctggt cgccgcggtt ctggccgaaa ggcaccccac ccccatggag agggtggcca
    13021 tgcaggacgt gttcgggcag tccggggaaa gcgatgagct catgaaggag tacgggctca
    13081 gcgaaaagga agttatagcc gccgccatca gggtcatgga gaggaagaaa tgaagatatt
    13141 catcgatacc gccaacatag agcagatcaa ggaggtgagc tcctggggca tcttggacgg
    13201 agttacgacc aaccccagcc tcatcgccaa ggagaagaag gacttcgcca ccatcgtgaa
    13261 cgagatatgc gaggtcgtgg acggcccgat aagcgtggag gttataagcc tcaaggccga
    13321 cgggatgttc gccgagggca tgaagctggc ggcggtcaac gagaacatcg tggtcaaggt
    13381 cccgatgacc gaggaaggcc tgaaggccac caagttgctc tcgaacgagg gcgtggcggt
    13441 caacatgacc ctcatattct cggccaacca ggcattgctg gcggccaagg ccggcgcccg
    13501 ctacgtctcg ccgttcgtgg gtagattgga cgacgtggga caggacggaa tggccctgat
    13561 ctcggacatc atggacatcc tggacaacta cgatttcgac accgaggtca tcgtggccag
    13621 cgttcgggac cccattcacg tgaccgacgc cgcccgcatg ggagcgcacg tggcgaccat
    13681 cccgttcgac gtgctgaaga agatgttcaa gcaccccctg accgacatcg gcatcgagcg
    13741 cttcctcaag gactgggaga aggtctccaa gccgtaggta aaaagtaaac cccttcccga
    13801 acctcatttt ttatcaggcg agaaccttga aatacgccgc ctcggatgga aacaggatga
    13861 agtgcgacgt gctggtggta ggcggaggtc cgaccggctg cctggccgcc gccagcatgg
    13921 ccggcgaact ggacgtgaag gtcctggagg aacatccggg agtgggagaa ccggtgcaat
    13981 gcgccggtct ggtcacgccc agggtggtgg agatggcctc cgcttccgac accgttctga
    14041 acaccatcga cggtgcttac gttcacttcc ccggcggaag ggtcatcgag ctgcagggca
    14101 actccgtgaa agcggtcgtg gtggaccgcg gggagttcga tcgccgctgc gcctccctgg
    14161 ccacgagaaa tggagcgcag gtgctgaccg ggagaaaggt cgcctcggtg gagaggacga
    14221 agagcggaat gaacgcccac acacccgagg aagaggtgga atgtgaggcg ttgctcgccg
    14281 ccgacggcta ccggtccgga gtggccagat cgcttgggtt cgccgccgcc aaagacatgg
    14341 tccgcgggct ggaggtcgat ctgcgcctga aggccgagga ccagcgcaag gtccgagtat
    14401 tcctgggcaa tgaggtggca ccgggcttct tcgcctgggc catcccttgc ggcgacctca
    14461 cccgggtggg gctgtgcgtt tccagggacc gaggcactcc ccaggagttc cttaccagat
    14521 tgcttgaggc ccaaggttgg ggggaagcgg aacgggttag gacctactcg ggagcgatcc
    14581 ccctgggtca catcccccgt acctacgcgg accgcgtcct ggtggccggg gacgccgccg
    14641 ggatggccaa gcccatcagc ggtggggggc tgttcaccgg catgaccgcc ggaaggctgg
    14701 ccgcggagac cttcctggaa gcgttccgtt cgaacgacct ttctgaaacg aacctttcca
    14761 aatacgagca aagatggaag gcggtctacg gcagtgagct tcgcagttcg taccgggtcc
    14821 gaaaggtctt cgtccgcatg agcgaccggg acctggacaa ggccggcgcc cggctggaca
    14881 acgagaaggc gaaaaatgtg ctggccaccg gggacatcga tttcccgacc gctctggcgc
    14941 ctggtctgct gaaggcctgc ccttcgctgc tgaccattgc cccgttgctg atcttccggc
    15001 tgctgtggag gtgagcgatg agagcattgt ccgttcccaa gtccgaggcc gacggggtga
    15061 aggacaagct caaccgccgc cggcagctgg acctcgagtg gagaccgggc agggcgggag
    15121 agatggtcct gcttccgctg atcggcgata acccttttcc cgagtacccg gtggtggacg
    15181 cggaactgca accccaggac cgccaccgcc cgccgcagga gaggatcgcc gagatattga
    15241 tgctcccgaa agagcttaat gccctattgc cagacaagta cgaacgactg gggcacgtga
    15301 tcgttctccg tcttccggac cagttgctcc cataccgcca ggagattgcg gccgcctacg
    15361 ctctcgttct caaggccaag acggtgctgt tggagaaggg catcatccgc ggggtggagc
    15421 gccggccgga catggagctg ttgttcggaa cggaaaccga gaccacccat tcggagtcgg
    15481 gcatcctgta ccgtttggac cctaccaagg tgatgttctc ctccggcaac ttcgacgaga
    15541 agctgcgcat ggcctcccta gactgccggg gcgagacggt ggtggacatg ttcgccggca
    15601 tcggctattt caccatgccc ctggccgcca aggcccgggc ggagcaggtc atcgcctgcg
    15661 agatcaaccc ggatgccata gggttcctga agaagaacat cgagctcaac caggtcgccg
    15721 atcgggtcac cgtcttcgag ggcgacaatc gccaactgcc cggggagggg ttcgccgacc
    15781 gggtggtcat gggctatgtg aacgtgacct ggcagttcct gcccaaggcc ttctcgatgg
    15841 tcaagagagg gggcatcatc cattaccagg acacctgctc cattgaccgg ataccggacg
    15901 gactgatcga aaacttgcgg aaaggcagcg gcggacggcc gttcgaggtc ctcgggataa
    15961 aggaggtcaa ggcctacgcc ccgtccatat cccacatggt gctggacgtc agggcgctct
    16021 gaccaccgtc tcactggaac cggattcctg cagcaaccgg agcagagcgc agtgatattc
    16081 ctcccgctcc gttcttagca gctcccgggc gtaaggggcg aaatgctccc cggactcacg
    16141 ctcctccttg gtgaactgcc atttgcgctg ctgagcctcg cccaccgcct ccaggaaggc
    16201 gtagca
//
LOCUS       DAOPZI010000031        16133 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_3848_length_16133_cov_9.433885, whole genome shotgun sequence.
ACCESSION   DAOPZI010000031 DAOPZI010000000
VERSION     DAOPZI010000031.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 16133)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 16133)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16133
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_3848_length_16133_cov_9.433885"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            98..298
                     /locus_tag="PKM11_06570"
     CDS             98..298
                     /locus_tag="PKM11_06570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48200.1"
                     /translation="MLTEDGKAMLARSVREYLRAYPGKKAEAKKRAVTHFLDYRMAFG
                     GGKVSKDLVTEVERYVDQVMSA"
     gene            complement(316..1044)
                     /locus_tag="PKM11_06575"
     CDS             complement(316..1044)
                     /locus_tag="PKM11_06575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48201.1"
                     /translation="MVDHTPDTTIILGRILNDRHGSRSSAVLNEIPNSRIRLLNEVYL
                     ETQSVIEKKAEFALSYLQRAFKEVSTEKGIDPADLAWEDVPEILKKARFLAHDRNEGF
                     FDSMEEFIDFVKQNMVYHPYDSLSAAYQNIIRSNKEKIRTIFGVQKIDQILVNEETIE
                     EDELRMEVESLLKGQIPSLSEKERDRDLRIVCQLFACSKKAHESTFNFIIIDNQLKVE
                     MPSVISIVKENFHERTGRITVQNA"
     gene            complement(1047..1775)
                     /locus_tag="PKM11_06580"
     CDS             complement(1047..1775)
                     /locus_tag="PKM11_06580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48202.1"
                     /translation="MSVESIDVAVHPIAALDNISGIFSTIAMLKAPLTGIPDRQIKVR
                     GLVRTNLKQMSNINKEEMERFLDGITDLFSTRMTVERMKEISKKIGNLDHLGKTLEKI
                     QNNYSSLSSPERVYYIKIASGVMIGDLEELEAKISLEAIRSDDIDKFRYLLVSQTIIQ
                     TILDHLKRTVRDSHSLADDVIEKQVNDIISLALFSIVRIEAFRRGKIDLESLRDTLSS
                     IVAHSTIQYHFPPITLPDEVITEE"
     gene            1975..3183
                     /locus_tag="PKM11_06585"
     CDS             1975..3183
                     /locus_tag="PKM11_06585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HNX48203.1"
                     /translation="MDIELVRKDFPLLQQEKPPIYLDSACQSLRPRQVMESMNEYYYD
                     FPACGGRSVHRLATEVSIRLDQAREDVASFVGVKDAECVIFTKSATESLNTVAKGLRL
                     KKGDRVVTTDMEHNSNHVPWVLLSKEKGIRRGYLSFQELEQGNLEPLKEELEKGVKVL
                     SVVHTNNVDGSTIPLKDVVELAHDHGALVMADGCQFAPHNRLDLTDTDVDFYAWSMHK
                     MLGPSGTGILYGKRDLLEDVTPLVTGGGGVSITTYDTAEILPIPERFEAGLQNYAGII
                     GSGAAVRYLERIGIDEIAEHEQRLNAVATEGLKGVRNLSMLGPSDPRRKGGILSFNLK
                     GMLPHDVAMILDEIASVLIRSGMHCVHPYFSSRGLEGCARASFYLYNTEEEVRTFIDA
                     VKYLSEKFTD"
     gene            complement(3173..3592)
                     /locus_tag="PKM11_06590"
     CDS             complement(3173..3592)
                     /locus_tag="PKM11_06590"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48204.1"
                     /translation="MMEFFISKFWAFLVSIFIMGVLVQGIQLDSRSERDEALVDLADD
                     LEVMFKEFAAAGKGMETTVHLDRSLPSTVTLTIFAGYASLQDGDREVRFSIPPFTMWM
                     ETEQGELLGVDRLVLGPTDSLRMRNEASGSTLIALSR"
     gene            complement(3589..4032)
                     /locus_tag="PKM11_06595"
     CDS             complement(3589..4032)
                     /locus_tag="PKM11_06595"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48205.1"
                     /translation="MRDDRRGIEGLPLRLVLVALLISLTLPTMISVMNQTTSDIAGEK
                     AAEIAKGIAATIEEMSAGGPGNVRMVNVPNDLLPGVSFTMGGESDSADCQRIRWNVNG
                     RQGDRYLVGAIIVTDDGKPILLTAGDSIRLECQTGAWGTIKAVKI"
     gene            complement(4037..4495)
                     /locus_tag="PKM11_06600"
     CDS             complement(4037..4495)
                     /locus_tag="PKM11_06600"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase-like regulatory
                     domain-containing protein"
                     /protein_id="HNX48206.1"
                     /translation="MSGDRDGGIEGLPLQLMIMVIVAGLGTAILVGWMGGLSAPEAIA
                     SVNGSPTEILLSDGDGDGTFENDDAKLTIIVRDQNGDPVEGASVVLDGCEVRNSDGSL
                     VYGTTGADGKVTFNDLSVSHFGNGIGFITVTVAKGGMGTDSSLQVPVICR"
     gene            4768..6159
                     /locus_tag="PKM11_06605"
     CDS             4768..6159
                     /locus_tag="PKM11_06605"
                     /inference="COORDINATES: protein motif:HMM:NF014805.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="HNX48207.1"
                     /translation="MFKKVLIANRGEIAIRVINTCKKMGVPTVGIYTPSDKHCKHVSL
                     ADKSVELKTDENSIGYLDIDAIIDVANRMKVDAIHPGYGFLSEKPELSERCEEEGIAF
                     LGPSPRAMKLLGSKLSAREFMSKVGVPIMPGTLDPLETPDEAIEQANKIGYPILLKAS
                     GGGGGRGMRLVHNDSEMENALTSAKNEADKAFKNPTIYLERALLKARHIEFQVVGDSR
                     GNAYCLGERECSVQRRHQKIIEETPSCAVSPELRAKMSELCIAAVKRANYTSLGTFEF
                     LMSAEGDLFFLEANTRIQVEHPITELVTGLDLVEMQLKIGSDVPVEDVLSEVVPKGHA
                     MEFRINAENPFNNFFPAPGRIEKYMEPAGEHVRVDSHAYEGYVVPTEFDNLLAKLIVS
                     GKTRNEVLIRGQDALDRYTVTGIKTTIPYHRLVVRNPDFRAGNYSIDYVKDHLPQDLL
                     KTTEFSLFEGVGR"
     gene            complement(6156..6707)
                     /gene="thpR"
                     /locus_tag="PKM11_06610"
     CDS             complement(6156..6707)
                     /gene="thpR"
                     /locus_tag="PKM11_06610"
                     /inference="COORDINATES: protein motif:HMM:TIGR02258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008664 - 2'-5'-RNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HNX48208.1"
                     /translation="MMSFRSFIAVDVECGEVLRDAINELQHFGRTLKPVSPDNLHVTL
                     KFLGDTDERCVPQLKKVMKEAVKDVTPFDVKLVGTGAFPNSRTARVIWVGMEGAEPFQ
                     DIVTKLEDGCDLMGFGRDKQVFSPHLTLARVREGFNADLGDFIKYGHEKDFGSFTVKS
                     LKLKKSVLTPEGPVYSDMAEVRF"
     gene            complement(6704..7270)
                     /locus_tag="PKM11_06615"
     CDS             complement(6704..7270)
                     /locus_tag="PKM11_06615"
                     /inference="COORDINATES: protein motif:HMM:NF014573.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HNX48209.1"
                     /translation="MKILAINGSPRKDGNTARLLKEITKDHADVDLDYVDLNDLKIKD
                     CQACYFCKKNDACALKDDMQRLYKKLREADALVIGSPVFFGVETANVRAFVDRLYALL
                     AFGDGPGKYVPRLKGDKVAISFVSCGSGKGKEVYANIKDRHFAMWANLGFKNVHTFVI
                     AGATPQGNVFELVDAQEMVKECQKLLEG"
     gene            complement(7408..>8391)
                     /gene="gdhA"
                     /locus_tag="PKM11_06620"
     CDS             complement(7408..>8391)
                     /gene="gdhA"
                     /locus_tag="PKM11_06620"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HNX48210.1"
                     /translation="LPMGGAKGGADFDPKGKSEAEIMRFCQAFMGELYRHIGPNTDVP
                     AGDIGVGGREIGYMFGQYKKMVNRFESVLTGKGINWGGSLVRPEATGYGCTYFCEEML
                     KTKRTNFNGKTVAISGSGNVAQYAVQKVTQLGGKVVTLSDSDGSIYDPAGIDVEKWKY
                     VMELKNVKRGRMSEYATKYGCEFWANERPWKAKCDIAMPCATQNELDKNDARRLLDNG
                     VIAVSEGANMPSTPEAVELFIANGVLFGPGKAANAGGVATSGLEMCQNHIGISWSAEE
                     VDRQLHQIMVNIHKNAADSARKYGSPGNYVVGANITGFVKVASSMMDQGLI"
     assembly_gap    8392..8491
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            8798..9997
                     /locus_tag="PKM11_06625"
     CDS             8798..9997
                     /locus_tag="PKM11_06625"
                     /inference="COORDINATES: protein motif:HMM:NF014692.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase iron-sulfur subunit"
                     /protein_id="HNX48211.1"
                     /translation="MNDSCLATVKINQDLCSRCKVCYSLCPFESIREKEDGRIEIDIQ
                     KCQVCGICYSACPASAIEMAYYDYDGLLDFVRNASPSASTLVMMCRGNSPSGGEVEDI
                     LADHGLDTKDYIPLRIPCAGRVPTDFIFRALSSGIRNIISIQCQDGFCRMKEGTRIET
                     RRLLLGQAVIRQFGYPDDSLQVVKYSRKAVWINHDCVGCDKCVFVCPYGAISADSISS
                     PRVDQEKCVGCGACQTVCPHHAIQVKGYEFYSVLRSYEEAAARLRQRDKRPSILVFSC
                     QWSEFSALDDPEKLLRGQNAMLLEVPCFKGLDPVHVVNALRNGFDGVLAVVCAPEDCK
                     LQKGGDNAVRQLDVLYGALKKLGLSERFELHEMSPRCGGDFNAVFEKFCERISDMYSD
                     ECQRRVG"
     gene            9998..10843
                     /locus_tag="PKM11_06630"
     CDS             9998..10843
                     /locus_tag="PKM11_06630"
                     /inference="COORDINATES: protein motif:HMM:NF004862.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HNX48212.1"
                     /translation="MYRIVSKERLAHKHTLFTVNAPEIAAKAQAGQFLIVISKEGGER
                     VPLSICAYDRQKGTVSFAFHEVGRTTKELGTFNEGDELFNVTGPLGNPSEIRNYGKVL
                     CVGGSIMIAPALLQAKALKEAGNEVVTVLACRSEEFLFKKAEAERFSDRVYLASDDGT
                     VGEKGLDFLNDLLAKERFDRCTVIGPVVMMKKVSEMTKPFGVPTIVSLTPIMIDGMGM
                     CGVCRVTVGDKMLFGCVDGPEFDGHQTNFDELIQRQRSMLPEERLSSMLWEHEHEGGC
                     RCGRK"
     gene            10830..12263
                     /gene="gltA"
                     /locus_tag="PKM11_06635"
     CDS             10830..12263
                     /gene="gltA"
                     /locus_tag="PKM11_06635"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: protein motif:HMM:TIGR01316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004355 - glutamate synthase (NADPH)
                     activity [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HNX48213.1"
                     /translation="MEGSEPRKRNDKALDEDVPMPRQEPEDRVKNFTEVALGYTEEMA
                     LAEAARCLKCKNPPCRKGCPVDIPIPQFIEKIIEGNYDEGISIIRSKNALPAVCGRVC
                     PQENQCQKNCIRGKKGDPVNIGRLERFLADREREKGMKVPERPAPTGKKVAIVGAGPS
                     GLVAAADLAKLGHEVTLFEALHVAGGVLMYGIPEFRLPKAIVQKEVEYVQSLGVELRL
                     GNLIGRIHTIPELMAQGYDAVYIGSGAGLPQWTGCPGENLGGIYSANEFLIRVNLMKA
                     YDFPETDTPIRIGKHVVVIGGGNVAMDCARISMRLGARVCLNYRRSRNELPARREEIE
                     NAEEEGLICNFLNAPVEFFGDDKGWVKTMRCTNMELGEPDDRGRCSVSPIACSDFDVE
                     TDTVIVAIGQTPNPIIQRTTDGLKTNPRNGTIIVDDDGRTSLDGVYAGGDVATGAATV
                     ISAMGAGKRAAQAMHDYLMNDKQGDRE"
     gene            12260..13231
                     /locus_tag="PKM11_06640"
     CDS             12260..13231
                     /locus_tag="PKM11_06640"
                     /inference="COORDINATES: protein motif:HMM:NF013242.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HNX48214.1"
                     /translation="MSKLKVAFYWAASCGGCEIAVLDINERILELVQHVDIVFWPVAM
                     DVKYKDVEAFPDGYIDITFLNGSIRNSEQEHMAKVLRAKSKTLVAFGACACEGSVPGL
                     ANLHDSKEILNQVYREIGDGGNDSLVPKPDSKVKEGTLHIPTFYDTVKTLNQTVDVDY
                     YLPGCPPPVDLINRALDAILSGNLPPKGSILAPLPAVCAECPRKRENKKITAIHRVYD
                     IVPDPERCLMEQGIICMGMATRSGCGAQCLKVDMPCTGCGGATPNQSDIGTGMMTALA
                     SILNLDKEPGTYTEEEVMELISQIKDPAGIFYMYSLPASILRRKVMK"
     gene            13228..14682
                     /locus_tag="PKM11_06645"
     CDS             13228..14682
                     /locus_tag="PKM11_06645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe hydrogenase subunit alpha"
                     /protein_id="HNX48215.1"
                     /translation="MKREIVIDPITRLEGHGNVSIFLDDQGEVENAYLKIPELRGFES
                     FCVGRPAELMPLLTTRICGVCPVSHHYASVKALDAAFHVDPPSAAKKLRELQYMGYIC
                     YDHTLHFYYLGGPDFIVGPDAPPEKRNILGVIEKAGLDVAKEVIKHRAYGQKITEIIG
                     GKATHPVSGLPGGMSKPLSEESRLAILEMSKSLVNFAQFTLKIFHQIVLDNPAYVDLI
                     KSEMYTQRTYYMGMVDSNNHVNFYDGKIRVVDPSGKEFAKFDAQDYQQHIEERSEEWT
                     YSKLPFLRKVGWKGFVDGPNNGAYRVGPLGRLNVAEGMSTPLANKEYQEMFSLLGKPV
                     HSTLAFHWARLIELLYAAEHAVELASDPEITSTDVRNRPGKPGEGVGIVEAARGTLIH
                     HYHLDDDALMKKVNMIVATTNNYPSICMSIRDAAKGLIHNGKVDERILNKVEMAFRAY
                     DPCFGCATHFAIGQMPLEVKVYGRHKELLCQLSR"
     gene            14708..15202
                     /locus_tag="PKM11_06650"
     CDS             14708..15202
                     /locus_tag="PKM11_06650"
                     /inference="COORDINATES: protein motif:HMM:TIGR00072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation protease"
                     /protein_id="HNX48216.1"
                     /translation="MRDHTIPLEDELRVWLEGASMVVVAGIGNGIRRDDFVGVKVVQD
                     LVGMVSENVHLIECETVPESFVDEIIDVAPSHVLLIDAALLGLAPGTAHLYDVEEVVN
                     STSISTHTLPLRVFCEYVFTLTGAKIALLLIEPLETDFGEGLSPELQGAAKDVSVILS
                     NLLS"
     gene            complement(15296..15463)
                     /locus_tag="PKM11_06655"
     CDS             complement(15296..15463)
                     /locus_tag="PKM11_06655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX48217.1"
                     /translation="MAVKVNVDECVGCGLCEDVCPSGAITVDDVAVIDAKKCTECGAC
                     IDECPNSAISK"
     gene            complement(15533..15958)
                     /locus_tag="PKM11_06660"
     CDS             complement(15533..15958)
                     /locus_tag="PKM11_06660"
                     /inference="COORDINATES: protein motif:HMM:NF012791.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HNX48218.1"
                     /translation="MEGKQLRLLVAVDGSVHGEKALRKAALLALSAPSYEIAVVCVVE
                     VREFASLMAEVDTEEMEVRAKKILQDSLEILTSEGVAATAHLLHGPPVTKILEFAESF
                     GPDLIVTGSRGMGAAKGALIGSVSSSLSKRANTSVLIVR"
     gene            complement(15940..>16133)
                     /locus_tag="PKM11_06665"
     CDS             complement(15940..>16133)
                     /locus_tag="PKM11_06665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48219.1"
                     /translation="DRVYIALLMSTSLTFGMVFLQFGLGQGLIDTTQFSILVGTIIIG
                     ALAPTLAAQRWFDPWRGSS"
BASE COUNT         3530 a         4542 c         4589 g         3372 t
ORIGIN      
        1 tggaagttca tgtacctgac ccggaccttc ttccgtataa gtactgacaa cccttaatag
       61 gtgtcgtgac aatagaaaca aactgggggt tcttaacttg ttgaccgagg acggtaaggc
      121 gatgctagcg aggtctgtcc gagagtacct gagggcgtac cccggaaaga aggccgaggc
      181 caagaagaga gcggtgaccc acttcctgga ctaccggatg gccttcggcg gcggaaaggt
      241 ctccaaggac cttgtcactg aagtggagag gtacgtcgac caggtcatgt cggcgtgacc
      301 tcatcccaat ttttttcaag cgttttgaac cgtgatccgc cctgttcttt cgtggaaatt
      361 ttctttcaca atagatatca cggatggcat ctctaccttc aattggttgt cgatgatgat
      421 gaaattgaag gtcgattcat gagctttctt cgaacatgca aaaagttggc atacgatcct
      481 gaggtctctg tccctctctt tttcagagag cgagggtatt tgccctttta agagagactc
      541 tacctccatg cgcagctcgt cctcctcaat ggtttcctca ttcactagta tctgatcgat
      601 tttctgcact ccgaagatcg ttctgatctt ctccttgttt gacctgatta tgttttgata
      661 tgccgcagat agagaatcgt agggatgata caccatattt tgtttgacga aatcgatgaa
      721 ctcctccatg ctgtcaaaga aaccctcatt gcgatcatga gccaggaatc tggccttttt
      781 caatatctct ggaacatctt cccaagccag atcggcagga tcaatacctt tttcagtgga
      841 aacctccttg aaagcccttt gcaggtaaga cagagcaaac tcagcctttt tttcaataac
      901 cgattgtgtt tccaaataaa cctcgttaag taagcgaatc cttgaattcg gtatctcgtt
      961 cagaaccgca ctcgaccttg agccgtgccg gtcattaagg atcctaccta gaatgatggt
     1021 cgtatctggt gtgtgatcga ccattttcac tcctcggtaa tcacttcatc aggaagagtg
     1081 ataggaggaa aatgatattg gatggtggag tgggcgacta ttgaagatag tgtgtccctc
     1141 agactttcaa ggtctatttt tcccctgcgg aaggcttcga tccggacgat ggagaacaac
     1201 gccaaagaga tgatgtcgtt aacctgtttt tctatgacat catcagccag ggagtgactg
     1261 tctcgcactg tcctcttcag gtgatcgagg attgtttgga tgatggtctg agaaaccaac
     1321 agatatcgga acttatcgat atcgtcggat ctgatagcct ctaacgatat cttggcctca
     1381 agttcctcca gatccccaat cataacgcca gaagcgattt taatgtaata gactcgttca
     1441 ggagagctta aactggagta gttgttttga attttttcca atgtctttcc caggtgatcc
     1501 aaatttccga tcttttttga aatctctttc attctttcaa cggtcattcg ggtggagaag
     1561 agatcggtta ttccatccag aaaacgttcc atttcttctt tgttgatatt agacatctgt
     1621 ttcagattgg ttctgactag ccctctcacc ttaatctgac ggtcgggaat gcctgttagg
     1681 ggagccttga gcatggcaat tgtgctgaaa atgccagaaa tgttgtcgag agctgcaata
     1741 ggatgaacag cgacatctat cgactcaacg ctcattggag acccctcatc atcgagattt
     1801 tgtgatgatt tatactttat ttgatgtttg tcactacaat caatgattta aaaatcatta
     1861 taaaatattt ttttcccgct tgtaaattaa ccagaatgat atttgcatga atttgtttta
     1921 tccagtaact acgacacctt aaataaagca gaaaccgttc ccagcccgac tggaatggat
     1981 atcgaactcg ttcgtaagga cttcccgctc cttcagcagg agaagccgcc gatctacctg
     2041 gacagcgcgt gccagagcct gcgcccccgc caggtcatgg aatcgatgaa cgagtactat
     2101 tacgattttc cggcctgcgg cgggcgttcc gttcaccgcc tggcgacgga ggtatcgata
     2161 cgcctggacc aggcgcggga ggatgttgcc tctttcgtcg gcgtgaagga tgccgagtgc
     2221 gtcatcttca cgaaaagcgc cacggagtcc ttgaacaccg tggccaaagg acttcgccta
     2281 aagaaaggtg accgggtggt gaccacggac atggagcata acagcaacca tgtgccctgg
     2341 gtgctacttt ccaaggagaa gggcatccgc cgcggatacc tttccttcca ggaactggaa
     2401 cagggaaacc tggaacctct gaaggaggag ctggagaagg gcgtgaaggt cctgagcgtg
     2461 gtgcatacca acaacgtgga cggaagcacc atccccctga aggatgtggt ggagttggcg
     2521 catgaccacg gcgcgttggt catggccgac ggatgccagt tcgctcctca caaccggttg
     2581 gacctcacgg acaccgacgt tgacttctac gcctggtcaa tgcacaagat gctcggccct
     2641 tccggcactg gcattctgta cgggaagcgg gacctcttgg aagacgtaac gccactggtc
     2701 acaggtggcg gcggagtgtc cataacgacc tacgataccg ctgaaattct gccgataccg
     2761 gaaaggttcg aagcgggatt gcagaactac gccgggatca tcggcagcgg ggcggcggtt
     2821 cgatatctcg agaggatagg catcgatgag atcgcggagc acgagcagcg cctgaacgcc
     2881 gtcgccaccg aaggactgaa gggcgtcagg aacctatcga tgctcggccc gtccgatccg
     2941 cgacgtaagg gcggaatact ctccttcaac ctcaaaggaa tgctcccgca cgacgtggcg
     3001 atgatcctgg acgagatcgc ctccgttctg atccgttcgg gaatgcattg cgttcaccct
     3061 tacttctcgt cgcgtgggtt ggaaggatgc gccagggcct ctttctatct ctacaacacc
     3121 gaggaagagg ttcgtacgtt cattgacgcg gtgaagtatc tatcggaaaa gttcaccgac
     3181 tgagcgctat caaggtcgat cctgaggcct cgttgcgcat ccgtagcgaa tcggtcgggc
     3241 ctagcaccag tctgtccacc cctagcagct cgccctgttc ggtctccatc cacatggtga
     3301 acggcggaat ggaaaagcga acctcgcggt ccccgtcctg caatgacgcg taaccggcga
     3361 aaatcgtcaa ggtcaccgtg gaaggcaaag agcggtcgag gtgtaccgtc gtttccattc
     3421 ccttaccggc cgcagcgaac tccttgaaca tcacttccag atcgtccgcc aggtccacca
     3481 gggcctcgtc gcgttcggaa cgggaatcga gctgtatccc ctggaccaat acgcccatga
     3541 taaagatgga caccaggaac gcccagaact tggagatgaa gaactccatc atatcttcac
     3601 cgccttgatc gttccccagg cccctgtctg gcattccaat cgtatggaat cgcctgctgt
     3661 gaggagtata ggtttaccgt catcggtcac tatgatcgcg cctaccagat acctatcccc
     3721 ctggcgcccg ttgacgttcc atcttatccg ttggcaatcc gcgctgtcgc tctctccccc
     3781 catggtgaac gaaacaccgg gaagaagatc gttgggaacg ttcaccatgc gcacgttgcc
     3841 gggacctccc gccgacatct cctcgatggt ggccgcgatc cccttggcga tctcggccgc
     3901 cttttccccg gcgatgtcgg acgtggtctg gttcatgacg gatatcatcg ttggtagcgt
     3961 cagagagatc agaagggcca ccagcaccag ccggagcggt agtccctcga tcccccttct
     4021 atcatctctc aaggtctcac ctgcagatca ctggcacctg tagcgacgaa tcggtgccca
     4081 ttccgccctt ggccacggtc acggtgatga aaccgatgcc gttgccgaag tgcgagacgc
     4141 tcagatcatt gaacgtgacc ttgccgtcag cacccgtggt tccgtacacc agtgaaccgt
     4201 ccgaattgcg cacctcgcac ccgtccagaa ctaccgatgc gccttccacc gggtcaccgt
     4261 tctgatcgcg tacgattatc gtaagcttcg cgtcgtcatt ctcgaaggtg ccgtcgccat
     4321 ccccatctga gagaaggatc tcagtaggac tgccgttcac ggatgctatg gcctccggtg
     4381 ccgagagccc gcccatccat cccaccagga tggccgtccc gagaccggcc acgatcacca
     4441 ttatcatcag ctgcagcggc agaccctcga tgccgccgtc ccgatccccg ctcatacgtt
     4501 tctttgagaa cctcatttta tctccgaaat agggaacgct gaggggtgtc tattggtgct
     4561 cgtttacagt aagactaact agcggaccgc attcgtcaac cgaaaaacga ttttaaacaa
     4621 taatattgct gattcttatt gtaaaacgaa tattccgtcc gaaatcaaaa gaaattcttg
     4681 gcaatgctaa tcgaaattat tataaaaaca agttacattc cctgccacgc agtcgcatgc
     4741 ggagccattg cgcctgaggt taaaaagatg ttcaagaagg tgctgatagc gaacagaggg
     4801 gagatcgcca tccgggtgat caacacctgc aagaagatgg gagtgccgac cgtaggcatc
     4861 tacaccccct cggacaagca ctgcaagcat gtctcgctag cggacaagag cgtcgagctg
     4921 aagaccgacg agaacagcat cggatacctg gacatcgatg ccatcataga cgtggccaac
     4981 cgcatgaagg tggacgccat ccaccccggt tatggtttcc tctccgaaaa accggagctc
     5041 tccgagcgtt gcgaggagga gggcatcgct ttcctgggac catctccgag agcgatgaag
     5101 ctcctcggtt ccaaattatc cgcccgggag ttcatgtcca aggtcggcgt tccgatcatg
     5161 cccggcaccc tggacccgtt ggagaccccg gacgaagcca tcgaacaggc caacaagatc
     5221 ggctatccca ttctgctcaa ggcatccggc gggggcggcg ggcgcggaat gcgcctggtc
     5281 cataacgatt cggagatgga gaacgcgttg acctcggcaa agaacgaggc ggacaaggcg
     5341 ttcaagaacc ccacgatata cctggaaagg gctctcctga aagcgaggca catcgagttc
     5401 caggtggtcg gcgattcccg cggcaacgct tactgcctcg gggagaggga atgctccgtg
     5461 caacgccggc accagaagat catcgaggag acgccttcct gcgccgtttc cccggaactt
     5521 cgggccaaga tgtccgagct gtgcatcgcg gcggtcaagc gggccaatta cacttcactg
     5581 ggaacgttcg aattcctgat gtccgccgag ggggacctgt tcttcctgga ggctaacacc
     5641 cgaattcagg tcgagcatcc catcaccgag ctcgttaccg gattggacct ggtcgagatg
     5701 cagctcaaga tcggttccga cgttccggtg gaggacgtgc tatcagaagt agtgccgaaa
     5761 ggtcacgcca tggagttccg catcaacgct gagaatccgt tcaacaactt cttccccgct
     5821 ccggggcgca tcgagaagta catggagccg gccggcgagc acgtccgcgt ggactcccac
     5881 gcctacgagg gttacgtcgt accaacggag ttcgataatt tacttgccaa gctcatcgtc
     5941 tccggcaaga ccaggaacga ggtgctgatc agaggccagg acgccctgga ccgctacacg
     6001 gtcaccggca taaagacgac cataccgtac caccgcctgg tcgtgcgcaa cccggacttc
     6061 cgggccggga actacagcat agactacgtc aaggaccact tgccgcagga cctgctgaag
     6121 accaccgagt tctcgttatt cgaaggcgta ggccgttaga agcgaacctc ggccatgtcc
     6181 gagtataccg gaccttccgg tgtcagcacg ctcttcttca gcttcaaaga tttaacggtg
     6241 aaggaaccga agtccttctc atgaccgtat ttgatgaaat cgcccagatc ggcgttgaag
     6301 ccttctctca ctcgcgctaa cgtcaaatga ggcgagaaga cctgcttgtc ccggccgaag
     6361 cccatcaggt cgcacccgtc ctccaatttc gttactatgt cctggaacgg ctccgcgccc
     6421 tccatcccca cccagatcac ccgggcggtt cgggagttgg ggaaggcgcc ggtgcccacc
     6481 agcttcacgt cgaacggggt gacgtccttc accgcctcct tcatgacctt cttcagctgc
     6541 ggcacgcacc gttcatccgt atcgccgagg aacttgaggg tgacatgaag gttatccggc
     6601 gataccggtt tcaacgtgcg tccaaaatgc tgcagttcgt tgatggcgtc ccgcaggacc
     6661 tcgccgcatt ccacgtccac cgcgatgaac gatctgaagc tcatcatccc tccagcagct
     6721 tctggcattc cttgaccatt tcctgggcgt ccaccagctc gaacacgttg ccttgcgggg
     6781 tggccccggc gatcacaaac gtatggacgt tcttgaaacc caggttggcc cacatggcga
     6841 agtgacggtc cttgatgttg gcgtagacct ccttgccctt gccgctgcca cagctgacga
     6901 aggatatggc caccttatct cctttcaacc ttgggacgta cttgcctggt ccgtcaccga
     6961 aggccagcag cgcgtagaga cggtcgacga acgctctcac gttcgcggtc tccactccga
     7021 agaacaccgg ggatccgatg accaaggcgt ccgcctccct gagcttcttg tacagtcgct
     7081 gcatgtcgtc cttgagggcg caggcgtcgt tcttcttgca gaagtaacag gcctggcagt
     7141 ccttgatctt gagatcgttg agatcgacgt agtccaggtc cacgtcggca tggtccttgg
     7201 tgatctcctt caacaatctg gcggtgttcc cgtccttgcg cgggctcccg ttgatagcta
     7261 gaatcttcat gatgacccct tagtaatcat cgacaggtgc tacaagggat aaaggattga
     7321 cgggtcgaca ggcaagttct gagcgaaatt tggaaaaagt gaaaggaacg cccggtccgg
     7381 ccgggacgtt caattgatca agatgtttca gatcaggccc tggtccatca tggaactggc
     7441 gaccttgacg aagccggtga tgttcgctcc gaccacgtaa ttgccggggc tgccgtactt
     7501 gcgtgccgag tcggccgcgt tcttgtggat gttgaccatg atctggtgca gctgacggtc
     7561 gacctcttcc gcggaccagg agatgccgat gtggttctgg cacatctcca ggccggaggt
     7621 ggcgacgccg ccggcgttgg cggccttgcc ggggccgaag agaacgccgt tggcgatgaa
     7681 cagctccacc gcctcagggg tggatggcat gttggctccc tcggaaacgg cgatgacgcc
     7741 gttatccagc agcctccggg cgtcgttctt gtccagctcg ttctgggtgg cgcagggcat
     7801 ggcgatgtcg cacttggcct tccacggccg ttcgttggcc cagaactcac atccgtactt
     7861 cgtcgcgtac tcgctcatgc ggccgcgctt gacgttcttc agctccatga cgtacttcca
     7921 cttctctacg tcaattcccg ccggatcgta tatggaaccg tcagaatctg aaagggtgac
     7981 gacctttccg ccgagctggg tgaccttctg cacggcgtac tgcgcgacat ttccggagcc
     8041 ggaaatggcg acggtcttgc cgttgaagtt ggttctcttg gtcttcagca tctcctcgca
     8101 gaagtaggtg cagccgtagc cggtagcttc cggccggacc agcgaaccgc cccagttgat
     8161 gccctttccg gtgagtactg actcgaagcg gttgaccatc ttcttgtact gaccgaacat
     8221 gtaaccgatc tcgcgccccc cgaccccgat atcaccggcg ggaacgtcgg tgttcgggcc
     8281 gatgtggcgg tacagctcgc ccatgaaggc ctggcagaag cgcatgatct ccgcttcgga
     8341 ctttcccttg ggatcgaagt ccgccccgcc cttggcaccg cccatcggca gnnnnnnnnn
     8401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngttgacgac ggggttggcg aacgaggttg
     8521 tcttatttaa tctgtgtttt gcgtttttca tctaattttt cttgaataat tgtacatttg
     8581 ctggatttta ttgctgaaaa tggcattcgg ttcgagtaaa tgttcagctt acgaactatc
     8641 gagcatatgc attaaataat aaggccatta tccaatcaag gtcgtagtgg acatgtacca
     8701 ttaaggtccc tggatgacgg ccgctcgatg cccgccctcg atgaaagcgg gacggtgcga
     8761 acgcagcgaa ttcctgggga ccgccgggtg atcattgatg aacgatagtt gcctcgccac
     8821 cgtaaagatt aaccaggacc tgtgcagccg ttgcaaggtg tgctactccc tctgtccgtt
     8881 cgaatccatt cgagagaagg aggacgggcg catcgagatc gacatccaga agtgccaggt
     8941 ctgcggcatt tgctatagcg cctgcccggc gtccgccatc gagatggcct actacgatta
     9001 cgacgggctt ttggatttcg ttcggaacgc cagcccctcc gctagtacct tggtcatgat
     9061 gtgccgcggc aactcaccga gcggcgggga ggtcgaggac atcctggccg atcatggact
     9121 ggacaccaag gattacattc cactgcggat accgtgcgct ggtcgggttc ccaccgattt
     9181 catattccgg gcgctgtcgt ccggtatcag gaacatcata tcgatacagt gccaggacgg
     9241 cttctgccgg atgaaggagg gcacccgcat cgagacccgc agactgctgc tcggccaggc
     9301 ggtcatcagg cagttcggct atcccgatga ttccctgcag gtcgtcaagt attcccgcaa
     9361 ggccgtctgg atcaatcacg attgcgtcgg ttgcgacaaa tgcgtcttcg tctgcccgta
     9421 cggggcgata agcgccgatt ccatatcctc gcccagggtg gaccaggaga agtgcgtagg
     9481 ctgcggcgcc tgccagacgg tatgcccgca ccatgccatc caggtcaagg gctacgagtt
     9541 ctactccgtc ctccgttcgt acgaggaggc ggcggctcgc ctgcgccaga gagacaagcg
     9601 gccatcgata ctggtgttca gctgccagtg gtccgagttc tccgctctgg acgatccgga
     9661 gaagttgctg cgcggacaga acgccatgct gttagaggtg ccgtgcttca agggattgga
     9721 cccggtacac gtggtgaacg cgctgcgcaa cggcttcgac ggcgtgctgg ccgtggtgtg
     9781 cgccccggag gactgcaagc tccagaaggg cggcgataac gccgtgaggc agctggacgt
     9841 actgtacggc gcgctgaaga agcttggtct ttcagaacgc ttcgagctgc acgagatgtc
     9901 gcctcgatgc ggcggcgatt tcaacgccgt gttcgaaaag ttctgcgaac ggatctccga
     9961 tatgtactcc gacgaatgcc agaggagagt gggctgaatg taccgcatcg tctccaagga
    10021 aaggttggcg cataagcaca ccctgttcac cgtgaacgct ccggagatcg ccgcgaaggc
    10081 gcaggccggg cagttcctta tcgtcatctc caaggaagga ggtgaacgcg ttccgctcag
    10141 catctgcgct tacgaccggc aaaaaggtac cgtatccttc gccttccacg aggtcggcag
    10201 gaccaccaag gaactgggca ccttcaatga gggtgacgag ctgttcaacg tcaccgggcc
    10261 gctcggaaat ccgtccgaga taaggaacta cggaaaggtc ctgtgcgtcg ggggcagcat
    10321 aatgatcgct ccggccctgc tccaagcaaa ggccttgaag gaagccggta acgaggtcgt
    10381 cacagttctg gcctgccgca gcgaggagtt cctgttcaag aaggcggagg cggagaggtt
    10441 cagcgaccgc gtatacctgg catcggacga cggcacggtc ggcgagaagg gattggactt
    10501 cctgaacgat ctcctggcca aggagaggtt cgaccgctgc accgtgatcg ggccggtggt
    10561 catgatgaag aaggtcagcg agatgacgaa accgttcgga gttccgacca tcgtatcgct
    10621 gacgccgatt atgatcgacg gaatggggat gtgcggcgtt tgtcgcgtaa ccgtcggcga
    10681 taagatgctc ttcggatgcg tggacggccc ggagttcgac ggccaccaga ccaatttcga
    10741 cgagcttata cagaggcagc gttccatgct gcctgaggaa aggctcagtt ccatgctctg
    10801 ggagcatgag catgaagggg ggtgccgctg tggaaggaag tgagccccgg aagcggaacg
    10861 ataaagctct ggacgaagat gtcccgatgc cccgccagga gcccgaggac cgggtgaaga
    10921 acttcacgga ggtcgccctc ggttacacgg aggagatggc gctagccgag gcggcgcgtt
    10981 gcctcaagtg caagaaccct ccctgccgca agggctgccc ggtagacatc ccgataccgc
    11041 agttcatcga gaagatcatc gagggaaact acgacgaagg catatcgatc ataagatcga
    11101 agaacgccct gccggccgtg tgcggccggg tctgcccaca ggagaaccag tgccagaaga
    11161 actgcatacg cggaaagaag ggcgacccgg tgaacatcgg ccgcctggag aggttcctgg
    11221 ccgaccggga aagggagaag ggcatgaagg tgccggaacg tcccgccccg accggaaaga
    11281 aggtggcgat agtcggcgcc ggcccgtccg ggctggtggc cgccgcggac ctggcgaagc
    11341 tgggtcatga ggttactctc ttcgaagctt tgcacgtggc cggaggggtg ctgatgtacg
    11401 gcattcccga gttccgcctg cccaaggcca tcgtccagaa ggaggtggag tacgtccaga
    11461 gcctgggcgt ggagcttcgc cttggcaatc tcatcggacg catccacacc atccccgagc
    11521 tgatggccca aggctacgac gcggtctaca tcggcagcgg cgccgggctt cctcagtgga
    11581 ctggctgccc cggggagaac ctgggaggca tctactccgc gaacgagttc ctcattcggg
    11641 tcaatctgat gaaagcgtac gatttcccgg agaccgacac gccgatacga ataggcaagc
    11701 atgtggtggt catcggcggc gggaacgtgg ccatggactg cgcccgcatc tccatgagat
    11761 tgggcgccag ggtctgcctg aactatcgcc gctcccggaa cgagctgccc gctcgtcgcg
    11821 aggagatcga gaacgccgag gaggaggggc tgatctgcaa cttcctgaac gccccggtgg
    11881 agttcttcgg cgacgacaaa gggtgggtga agaccatgcg ctgcacgaac atggagctcg
    11941 gcgagcctga cgaccgtgga cggtgcagcg tttcgccgat agcctgctcg gacttcgatg
    12001 tcgaaacgga cacggtgatt gtggccatcg gtcaaactcc gaacccgata attcagcgca
    12061 ccaccgacgg actgaagacc aatccccgga acggcacgat catcgtggac gatgacggac
    12121 ggaccagctt ggacggggtt tacgccggcg gggacgtggc taccggagcg gcgacggtca
    12181 tcagcgccat gggggccgga aaacgagccg ctcaggccat gcacgattac ctaatgaacg
    12241 acaagcaggg ggaccgcgaa tgagcaagtt gaaggtggca ttctactggg cggccagctg
    12301 cggcggctgc gagatagcgg tcctggacat caacgaacgg atattggagc tggtacagca
    12361 cgtggacatc gtgttctggc cagtggccat ggacgtcaag tacaaggatg tcgaggcctt
    12421 cccggacggc tatatcgaca tcacgttcct caacggttcc ataaggaact cggagcagga
    12481 gcacatggcc aaggtcctgc gggccaagag caagaccctg gtggcgttcg gcgcctgcgc
    12541 ctgcgagggt tccgtccccg gactggcgaa cctgcatgat tcaaaggaga tactgaacca
    12601 ggtctacagg gagatcggcg acggcggtaa cgattcactg gtaccgaagc ccgattcgaa
    12661 ggtgaaggaa ggcaccctgc acatcccgac cttctacgac accgttaaga cgctcaacca
    12721 gaccgtggac gttgactatt atctgcccgg atgcccgccg ccggtcgacc tcataaacag
    12781 ggccctggac gccatccttt ccggcaatct gccgccgaag ggttccatac tggccccgtt
    12841 gccggcggta tgcgccgagt gcccgcgcaa gcgggagaac aagaagatca ccgccattca
    12901 ccgtgtctac gatatcgtcc ccgatccgga gagatgcctc atggaacagg ggataatctg
    12961 catggggatg gccacccgca gcggctgcgg cgcgcaatgc ctgaaggtgg acatgccctg
    13021 caccggttgc ggtggcgcca ccccgaacca gtcggacatc ggcacgggaa tgatgaccgc
    13081 cctggcctcc atattgaact tggacaagga acccgggacc tatacggagg aagaagtgat
    13141 ggagctcata tcgcagatca aggacccggc tgggatattc tacatgtaca gccttccggc
    13201 gtccatactc agaaggaagg tgatgaaatg aagagggaga tcgtcatcga tcccataacc
    13261 cgtttggaag gccacggcaa cgtctccata ttcctggacg accagggtga ggtggagaac
    13321 gcttatctca agatacccga actgagaggg ttcgaatcgt tctgcgtcgg ccgcccggcg
    13381 gagctgatgc ccttgctgac cacccgcata tgtggcgttt gcccggtgtc acaccattac
    13441 gcttccgtca aggcgttgga cgcggcgttc catgtggacc cgccgtcggc cgcaaagaaa
    13501 cttcgggagc tgcagtacat gggctacatc tgctacgacc acaccctgca cttctattac
    13561 ctcggaggac cggacttcat agtcggtccg gacgcccctc cggagaagcg gaatattttg
    13621 ggcgtgatag agaaggccgg cctggacgtg gcgaaggagg tcatcaagca ccgcgcctac
    13681 ggtcagaaga tcacggagat cataggcggc aaggccacgc accccgttag cggactccca
    13741 ggcggcatga gcaaaccgct cagcgaggaa tcacgcctgg ccatactgga gatgtccaag
    13801 tcgctggtga acttcgcgca gttcaccctg aagatattcc atcagatcgt gctcgacaac
    13861 ccggcgtacg tggacctcat caagagcgag atgtacactc agcggacgta ctacatgggc
    13921 atggtcgatt cgaacaatca cgtcaacttc tacgatggta agatacgtgt cgtcgatcct
    13981 tccggcaagg agttcgccaa gttcgacgct caagattatc agcagcacat cgaggagcgt
    14041 tcggaggagt ggacgtattc gaagctgccg ttcctgcgca aggtgggctg gaagggattc
    14101 gtcgacgggc cgaataacgg agcgtaccgc gtcgggccgc tgggaaggct gaacgtggcg
    14161 gagggaatgt ccacgccgct ggcgaacaag gagtaccagg agatgttctc cctgctcggt
    14221 aaaccggtgc acagcacctt ggccttccac tgggcccggc tgatagagct gctctacgcg
    14281 gccgagcacg ccgtcgagct ggcatccgat ccggagatca cctccaccga tgttcgcaac
    14341 agacctggaa agccgggcga gggcgtcggc atcgtcgagg ccgctcgcgg aactctcatt
    14401 caccattatc atctggacga cgacgcgttg atgaagaagg tcaacatgat cgtcgcgacg
    14461 accaacaact acccctcgat atgcatgagc attcgagacg ccgccaaggg tctcatacat
    14521 aatggtaagg tggacgagcg catactcaac aaggtggaga tggccttccg ggcctacgat
    14581 ccgtgcttcg ggtgcgccac gcacttcgcc ataggtcaga tgcccctgga agtgaaggtg
    14641 tacggtcgtc acaaggagct actgtgccag ttgagccgtt gatgtctgtc gccaaggagt
    14701 gagaggcgtg cgggaccaca ccatcccact ggaggacgag ctccgcgttt ggctggaagg
    14761 cgccagtatg gtcgtcgtcg ccggaatagg caacggcatc cgtcgggacg atttcgtcgg
    14821 agtgaaggtc gtacaggacc tggtcggaat ggtatccgag aacgttcacc tcatcgagtg
    14881 cgagacggtg ccggagagct tcgtggacga gataatcgat gtggcgccga gccatgtcct
    14941 gctcatcgat gccgctctgt tagggcttgc cccaggtacc gcgcacctct acgatgtgga
    15001 ggaggtcgtg aactccacca gcatctccac gcacacttta ccgttacggg tgttctgcga
    15061 gtatgttttt actttgaccg gggcgaagat cgccctgctt ttgatcgagc cgttggaaac
    15121 cgacttcggg gaaggactgt cgcccgaact tcaaggggcg gccaaggacg ttagcgtaat
    15181 tctctcgaac cttctctcct gagttcgtat agaaatcttc agcgatcgct cttttaagaa
    15241 ataatgaaaa catagggata aggggtttat ccggtggtcg gagaccaact ggaatttact
    15301 tggagatagc gctgttgggg cactcgtcga tgcaagcgcc gcactcagtg cacttcttgg
    15361 cgtcgatgac ggcgacatca tcaacggtaa ttgccccgct ggggcaaaca tcctcgcaaa
    15421 gtccgcaacc aacacactcg tcaacattta cctttacagc cattgtaaag cacctatgga
    15481 agggtggaag aaaagttacg gtatttattc tttaccttat ctggattgca tatcacctaa
    15541 cgataaggac cgaggtattg gcccgcttgg atagggatga tgatacgctt ccgatcaaag
    15601 cgcccttggc agctcccatt ccccggctgc cggtgacgat gaggtccggt ccgaacgact
    15661 cggcgaactc cagtatcttg gtcaccggag ggccgtgcag aagatgggcc gttgcggcca
    15721 cgccttcgga cgtcagtatc tccagggagt cctgcaggat ctttttggcg cgaacttcca
    15781 tctcctcggt gtccacctcg gccatcaagg aggcgaactc ccggacctcg acaacgcaga
    15841 ccacggcgat ctcgtaggag ggtgcggaca gagcaagcaa ggccgccttt cgcagcgcct
    15901 tctccccatg gaccgaaccg tccaccgcca ccaacagcct caactgcttc ccctccatgg
    15961 atcgaaccac ctctgggccg ctaacgtcgg cgcgagcgcc cctatgatta ttgttccgac
    16021 caatattgag aattgcgtcg tgtcgatgag gccttgcccc aatccgaact gcaggaacac
    16081 cattccgaaa gttaacgacg tggacatcag cagggcgatg tacacccggt cct
//
LOCUS       DAOPZI010000032        15435 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_4117_length_15435_cov_7.351951, whole genome shotgun sequence.
ACCESSION   DAOPZI010000032 DAOPZI010000000
VERSION     DAOPZI010000032.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 15435)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 15435)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15435
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4117_length_15435_cov_7.351951"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(159..1223)
                     /locus_tag="PKM11_06670"
     CDS             complement(159..1223)
                     /locus_tag="PKM11_06670"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013227.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HNX48220.1"
                     /translation="MDREMIEAATSALQNERLVMGESVFKFEEAFAKYVGVKHAVSLS
                     SGTDALIIALTAMDCVGKEVVTTPFSFIATANCIIHALGTPVFHDARAIDYNLDTKGL
                     DKAFTKNTRAVMPVHLFGHPCDMNAINDLAEERGAMVIEDACQAHGAIYNGKKAGALG
                     HVGCFSFYPTKNMTVGGDGGMVTTDDEDLSKKVAKYRDCGRVTRYLHDVVGFTSRLNN
                     CNAAIGLVQLKRLDQWNDNRRKIAKRYDQKLKDIAGITLPPKAGKGKDPVYHLYVIRA
                     DRRDDLAKQMTEAGIVTAVHYPVPIHLQPAYVERYGYKNGSFRVSEGLSQQVLSLPMF
                     PSMSNEQVDRVCETVVKFYR"
     gene            1375..2352
                     /locus_tag="PKM11_06675"
     CDS             1375..2352
                     /locus_tag="PKM11_06675"
                     /inference="COORDINATES: protein motif:HMM:NF013567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HNX48221.1"
                     /translation="MRVGVIGVGSMGKNHVRVYSEIAELVGVTDVMQDSSRSVADKFG
                     VRSYETPQDLLKDVDAVSICTPTSEHLKVARLAIEQGVHLLVEKPFTGTSGNAAELVE
                     LADKANVTLASGFIERCNPIVGNLRNLAAGKRFGDVISIASRRVSSFPARIRDVGVIM
                     DLGIHDVDVLRNVKGSEVRSVYALGGSYNTDKCEDFANLLLEFEDGGLGFIEVNWLTP
                     MKVRRISLTCSEAFVQADYIDQSMEISSSSIKDLDPNNLFNLPLELDVHRIAVKKEEP
                     LKVELENFLKAASAGKEASISGRDAVSNLKVCEAALRSLKSKGKEKVEV"
     gene            complement(2349..3641)
                     /locus_tag="PKM11_06680"
     CDS             complement(2349..3641)
                     /locus_tag="PKM11_06680"
                     /inference="COORDINATES: protein motif:HMM:TIGR03026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003979 - UDP-glucose 6-dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HNX48222.1"
                     /translation="MHGKIVAVVGLGYVGLPLACSFASTGIRTIGHDIVATKVEKIDS
                     GINPIEGDEPGLSELLAEVHAKGLLSASLDPSVLKEADAVFVSVDSPVDENKIPNLKF
                     LKSAVATIAANMKPGALLSIESTIPPGTMQNLVIPTIKETRGFLPGKDYLLVHCPERV
                     MPGRLLRNIKEYDRILGAYDKRSADVAEDLYARIVQGKIHRTSLINAEITKTTENAYR
                     DVQIAFANEVALLCEELGADVFEVRKLVNSCPFRDMHIPGSGVGGYCLPKDPWLLLSA
                     AKETRKEVIPAARRVNEYMPVHMIELVQKAFKERKLAGKPKVAIMGLSFLRDSDDTRN
                     SPSLVIIDLLEKNNDLIVHDPFVQKPYKAEMVRDVEKALKGADCAVFVTDHSCYKDLD
                     LKKVKELMRTPIIVDGRNIFDKAFCENLGYLYKGIGKG"
     gene            complement(3698..4150)
                     /locus_tag="PKM11_06685"
     CDS             complement(3698..4150)
                     /locus_tag="PKM11_06685"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF012360.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HNX48223.1"
                     /translation="MKLMAKYYSIIDCQIGDETIIRDYVNLYGCKIGKECRIAAFVEI
                     QRGVTIGDRCKVEAFAFIPSGVTIEDEVFIGPRATFTNDLHPHAVGDWSITPTVVKKG
                     ASVGAGAVIVCGVTIGENATVGAGAVVTKDVPAGATVVGNPAKPVKKK"
     gene            complement(4315..>4953)
                     /locus_tag="PKM11_06690"
     CDS             complement(4315..>4953)
                     /locus_tag="PKM11_06690"
                     /inference="COORDINATES: protein motif:HMM:NF014411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HNX48224.1"
                     /translation="PSQVSVDHLIHEGVTSGVHVVGDTMTEVLLDVGPRIKDEVLGEL
                     GVEKGGYILCTIHRQENADDRRNMEEIIGAMLESVETFVLPLHPRTRKNLAGWDMLRV
                     LEEAKNIVLTEPKNFMAFTALEKNAYKIMTDSGGVQKEAYFFGVPCVTVRDETEWVET
                     LEDGWNVLTGAHRERIVEAVSRDAPTAQRRTSYGDSKVSERIVSFLENEILF"
     assembly_gap    4954..5053
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(5222..6379)
                     /locus_tag="PKM11_06695"
     CDS             complement(5222..6379)
                     /locus_tag="PKM11_06695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48225.1"
                     /translation="MKERILIISFSDMKNDPRVYRQIIHLRKNYKVMTAGFAGPEIDG
                     VPFYRIGVHRNLPAKLARAMWLKTGRFDRYYERSFDASDLLDHVHPEDIDLVLANDND
                     SLPLAFSFGPTPVIHDAHEYSPRQYEDRAMWRFLEQKYRVQMCERYLPGCAGTITVCP
                     GIAEEYHKVYGIDPIVITNSTEYRDMIPNPVEPDNIRIIAHGIANPSRHIESMIEVMD
                     LTDHRFSLDLMLVPTNQKYYRKLQRMVQDRENVRLIPPVPMADIVPHTNGYDIGLHII
                     QPHNFNQLHSLPNKLFEFIQARLAVAIGPSPEMAYYVKKYGCGIVAKDFEPRSMAEAL
                     NSLDAESIAQMKARSDQAASEVTSENNMKALDDIVERVLSSRVGKTPHIVP"
     gene            complement(6522..7709)
                     /locus_tag="PKM11_06700"
     CDS             complement(6522..7709)
                     /locus_tag="PKM11_06700"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX48226.1"
                     /translation="MSIKVVVLDLHQFDDNRISKHIATVRESYELFRINFNFYPDRPS
                     PKTTKDAVTFNLSPSKNHYLNGALFDLRTMLGWGISRLERMLRSEFVKNGDQIILHVH
                     DPYLLGLAGKLSKRFGDAPIIYDRHEYFEAWKNRLGFSVAGMYEKWYGKHVTEVIFVS
                     RNYHDLPGVFAGKPVTIIPNYPPGQFSNKEAVERKVRDLGPDSIIDSVYFGSLNLSFD
                     RDIELQFRVLRSLMESDPRVRFTVAGRMYDPQVQSLVDSMISEFGERMRYLGEIPYQD
                     VIRLTQSSHLGFLFMRSDSPVWSESRPSSPNKVFENLLSGTIPVVKANLDDRAVIEKC
                     SLIFGKDSTFEEIRDQVLQLIGDRERMKRMMMECYETSLEFTWEWVAGRYIECYERVL
                     KEE"
     gene            complement(8030..8284)
                     /locus_tag="PKM11_06705"
     CDS             complement(8030..8284)
                     /locus_tag="PKM11_06705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48227.1"
                     /translation="MVLVKVVERWSDHQVRTEHVLGPDQFLQYLLKILMEVTNLEIKY
                     LAMIIIQPPVLNHGQELGPQSAPRHAKGKRALGGGKNHPA"
     gene            complement(8284..8586)
                     /locus_tag="PKM11_06710"
     CDS             complement(8284..8586)
                     /locus_tag="PKM11_06710"
                     /inference="COORDINATES: protein motif:HMM:NF014757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /protein_id="HNX48228.1"
                     /translation="MGVQICTVLLKAGYDVVLKTRSPERMEGTRESVTNSLLKSMAED
                     ESRKLLKNLRLTVSFQDLADRDISIEAVKEDAKVKTDNLKAVSFILNALVTSRANT"
     gene            complement(8712..9560)
                     /locus_tag="PKM11_06715"
     CDS             complement(8712..9560)
                     /locus_tag="PKM11_06715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48229.1"
                     /translation="MKLILGHNQFLGISHTSESSASEKDRLFSDPSKILEVVKIANEN
                     GFDTMVIEAHPRMRAFMDLYEKDGTFDMKFLLQVPYVSGYVRRMAESGIKGIVKEIIT
                     DAPVTSLLATPFQLLPKLIRSDYMGMGVKALDLETSKYSQYDISGVLMHNVVSDLLLS
                     FDGESAFGDYFDSVRRRFGVNAGLITLNLEMMVGQLKEWGLRPGTVITPINPYGFDMN
                     PSKESVEKVVNTSDLDIYAMNIMGGGSIPLAVSSEYLRGLQGLSGVIVGASSRKHIEE
                     LSRTFK"
     gene            complement(9560..10591)
                     /locus_tag="PKM11_06720"
     CDS             complement(9560..10591)
                     /locus_tag="PKM11_06720"
                     /inference="COORDINATES: protein motif:HMM:NF014893.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HNX48230.1"
                     /translation="MDKVRTGIIGAGKMGILHTCLFNKIPGSSLVAICDTAPLNLRLL
                     RSALPKATMYDDFNHMLESAELDLVVVTTPVFLHHRMAMTALKKGIAVFMEKPLALNG
                     DQSLELAVASEKTTTCVGYCRRFMATYQMAKSMLEIEQLGKVKSFSSHMFVTQNIDES
                     TGWQYDPKKSGGGVLMDLGSHAFDMVHYLLGDVQYVSATALATMPSGVETSTHVDLEL
                     RNGLSGSLDVSWSEPGFRLPEMMMDIRTEFGRIRVCEKYIEVIDDRETVPEKRERTIY
                     KQHIEKGVHINIGGPEYTREDMHIIDSILKNTPTICDFTEAAKTNYVIEAGYSSIKKA
                     SDRVAPRSI"
     gene            complement(10676..11392)
                     /locus_tag="PKM11_06725"
     CDS             complement(10676..11392)
                     /locus_tag="PKM11_06725"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX48231.1"
                     /translation="MITTPDEKNILIDAGSFDTFKSTAVFLDDLNVTKIDAFIITHPH
                     PDHVSFAVEVLNMCEVERIYMPGNSDNLEPMLWSSVMNATVAEGCPVYNDTTISPGDY
                     LEISDEVTFRVMWIDSNATRINDSCIVIRMDYRETSFLFTADIEWVAEAAMMDLGFDL
                     DVDVLQVSHHGVNSGTSSEFLNASTPEVAIISCGQGYGIPLVPQPGVIERLSGIPTYV
                     TMFNSMVVVEAGNGYSISFI"
     gene            12035..13306
                     /locus_tag="PKM11_06730"
     CDS             12035..13306
                     /locus_tag="PKM11_06730"
                     /inference="COORDINATES: protein motif:HMM:NF012271.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="HNX48232.1"
                     /translation="MIISCMVLSGTLFLTNDASAAPIGAPLPPSNLTAVGDYGEITLR
                     WQAPSGSITAKSYVVYRSYYGGMSVIGGTSNTFFVDTQVSNGQGFSYQVAAVSGTNES
                     DKSSMAYARAGSVPLAPFNLVGQGYDERAFLSWAAPDNGGFSIQSYNIYRSNNSLSYY
                     LIGNAYGNSYNDYELTNGHDYRYQVAAVNELGVGPRSSIVTVTPMTTPSNPGGLRVYY
                     DDASAYLVWNEPLDDGGAEITEYRIQCRVQNRVWSIETGSAVTEYWIKDLVNGYTYEF
                     TVAAVNAAGVGGYTLSVSSDVFTVPTPVTNLKAYAGEENVMLTWNLPGYDGGSSVTHF
                     AVYRSTSAGGGYSLIGITNVTAYADLELDGGTKYYYRVASGNAVGLGEMSDQVSAEPS
                     NPPVPWVAVIIVAAVLAAMVVGVVLQWRKKA"
     gene            13446..13805
                     /locus_tag="PKM11_06735"
     CDS             13446..13805
                     /locus_tag="PKM11_06735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48233.1"
                     /translation="MASKLLFILICCVVTLFLLLPTIAQPTVGETGFDLDGSIGRSSG
                     VVIPQPMVLTVANIAGNPESLDPAVDFETVGGEVIQNVYETLHRQVQSLSGRHLDEEV
                     VDPVDQPISVLGPGDIL"
     gene            complement(13820..14809)
                     /gene="rfbB"
                     /locus_tag="PKM11_06740"
     CDS             complement(13820..14809)
                     /gene="rfbB"
                     /locus_tag="PKM11_06740"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: protein motif:HMM:TIGR01181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HNX48234.1"
                     /translation="MKLLVTGGAGFIGANYIRSNINGNNDIVCLDLLTYAGNLDNLDG
                     VIGKDNFTFVRGDINDRSFVRDLFKKEHFDRVVHFAAESHVDRSIEDPSSFLRTNVLG
                     TQNLLDACREFGIERFHQVSTDEVYGDLPLERKDLKFTEEYPIVPSSPYSASKASADL
                     LCHAYYRTFNVPITISRCSNNYGPYQFPEKLIPRMIVLALRNEKLPVYGKGENVRDWL
                     HVSDHCSAIDAILSKGKVGEVYNIGGNCERRNIDIVKLILRQLGKPEDLISFVKDRKG
                     HDLRYAIDNGKISRELGWSPAVRFEKGMRDTIDWYLSNETWLKRIESGEYRAD"
     gene            complement(14809..15348)
                     /gene="rfbC"
                     /locus_tag="PKM11_06745"
     CDS             complement(14809..15348)
                     /gene="rfbC"
                     /locus_tag="PKM11_06745"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: protein motif:HMM:TIGR01221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HNX48235.1"
                     /translation="MPELIVIEPKVFQDSRGWFFESYSVRNVRPQGIDVEFVQDNHSY
                     SERKGVIRGLHYQAPPFDQSKLVRCTRGSVLDVAVDIRHGSPNYAKWFGLVLSADNKK
                     QLFIPKGFAHGFLTLEDGCEVQYKVDNFYSYEHDRNIRYDDSEIGVEWGVSEPLLSDK
                     DLKAPSLRERGTDFIWEGR"
BASE COUNT         3310 a         4214 c         4153 g         3658 t
ORIGIN      
        1 gaagggagtt ggctgggtct caattggatt ggaacatcat cgctcagaag agtgtaaatt
       61 attatcaagg tcagatcgat ggaaagaagt aacgaggacc atgatttgta cctccataaa
      121 tgaagttcca ggggttcccc tggtgaattt tttttggatc atctgtagaa tttgaccacg
      181 gtctcacaga ctctatccac ctgctcgttg gacatggaag ggaacatcgg caacgacagg
      241 acctgttggg atagcccctc gctaaccctg aaggacccgt tcttgtatcc atagcgttcc
      301 acgtacgccg gctgcaagtg aatcggcact gggtaatgaa ccgccgtcac tatgcccgcc
      361 tcggtcatct gcttggctag gtcgtcgcgt ctgtccgccc ggatcacgta gaggtgatac
      421 accggatcct ttcccttgcc cgccttgggg ggcaaggtta tgcctgcaat gtccttcaat
      481 ttttgatcgt acctttttgc tatcttccga cggttatcgt tccactggtc caatcgcttc
      541 aactgaacca ggccgatggc ggcgttgcag ttgttcaaac gggaggtgaa gcccaccaca
      601 tcgtgcaggt atctggtcac ccggccacaa tcgcggtact tggccacttt tttcgatagg
      661 tcctcatcgt cggtggtgac catcccgccg tcccctccga cggtcatgtt cttggtgggg
      721 tagaaggaaa agcatccgac atggcccagc gccccggcct ttttaccgtt gtagatggct
      781 ccatgcgcct ggcatgcgtc ttcgatgacc atagccccgc gttcctccgc taggtcgttg
      841 atggcgttca tatcgcaggg atgaccgaac agatgaacag gcattaccgc cctggtattc
      901 ttggtaaatg ccttgtccaa gcccttggtg tccaggttgt aatcgatggc tctggcgtca
      961 tggaacaccg gggtgcccaa ggcatggatg atacaattgg ccgtagcgat gaatgaaaag
     1021 ggggtggtca cgacctcctt tccaacgcag tccatggccg tcaaggcgat gatcagggca
     1081 tctgtccctg aggacagtga tacggcgtgc ttcacgccaa cgtatttggc gaaggcctct
     1141 tcgaacttga aaacgctctc tcccatcacc agcctctcgt tctgcagggc agatgtggcg
     1201 gcctcgatca tctctcggtc catctcaggt ttggcaggag gaatctggtc catagtgaaa
     1261 gccttcggtc tatcggtgtc cttacaccta tcccagttga ataatttcaa tctatatgat
     1321 gattctgcaa aaaaagcgaa atcaatatct aatggcgagg aagtaaaccc agccatgcgt
     1381 gtgggtgtga tcggtgtagg ttcgatgggc aagaaccacg tccgggttta ttctgagata
     1441 gccgaactgg tcggagtgac ggacgtgatg caggattcat ccagatcggt cgccgataag
     1501 ttcggggtga ggtcctatga aacccctcag gaccttctga aggacgttga cgcggtcagc
     1561 atctgcactc caacgagcga gcatctcaag gttgccaggt tggccatcga acaaggcgtt
     1621 cacctgctgg tggagaaacc gttcaccgga accagcggaa acgccgccga actggtggaa
     1681 ctggccgata aagcgaatgt caccttggcc tcagggttca tcgagagatg caatcctata
     1741 gttgggaatc ttcgcaatct cgcggccggc aagcgcttcg gcgacgtgat atccattgcc
     1801 tctcgccgag tctcctcgtt ccccgcccgg atcagggatg tgggggtcat catggacctg
     1861 ggcatccacg acgtggacgt acttcgtaac gtgaaagggt ccgaggtacg ttccgtctac
     1921 gctctcggcg gttcttacaa caccgacaag tgcgaggact tcgccaatct gcttctggag
     1981 ttcgaggacg gcgggcttgg tttcatcgag gtcaactggc tcacccctat gaaggtcagg
     2041 aggatttcgc tcacctgcag cgaggccttc gtacaggcgg attacatcga ccaatccatg
     2101 gagatatcct ccagctcgat aaaggacctt gatccgaaca acctgttcaa tctgcctttg
     2161 gagctggacg tgcaccgtat cgccgtgaag aaggaagagc cgctcaaggt cgagctggag
     2221 aacttcctga aggcggcgag cgctggaaag gaagcctcga tcagcggacg ggacgcggtg
     2281 tccaatctga aagtatgcga ggcggcgttg cgttccctga agagcaaggg caaggagaag
     2341 gtggaggtct aacccttccc tatccccttg taaagatatc ccaggttctc gcagaacgcc
     2401 ttgtcaaaga tgttacggcc gtcgacgatg atcggcgtcc gcatcagttc ctttaccttc
     2461 ttcaagtcca ggtccttgta gcaggaatgg tccgtgacga acacggcgca gtcagctccc
     2521 ttcagagctt tctcgacgtc tctgaccatt tccgctttgt acggtttttg cacgaagggg
     2581 tcgtgaacga taaggtcgtt atttttttcc aggagatcga tgatgaccag gctcggcgag
     2641 ttgcgagtat cgtccgaatc ccgcaggaag ctcaggccca taatcgccac tttaggcttg
     2701 cccgccaact tcctttcctt gaacgccttc tgaaccagct ctatcatgtg cactggcatg
     2761 tactcgttca ccctgcgcgc tgccggtatg acctccttgc gggtctcctt ggccgcgctg
     2821 agcaggagcc aggggtcttt tggcaggcaa taaccgccaa cgccggagcc agggatatgc
     2881 atgtcccgga acgggcagct gttgaccagc ttccgcacct cgaagacgtc cgccccgagc
     2941 tcctcgcaca acagcgccac ttcattagcg aaggcgatct ggacgtcacg gtaggcgttc
     3001 tcggtcgtct tggttatctc ggcgttgatc agagaggtcc ggtggatctt gccctgcacg
     3061 atcctggcgt aaagatcttc cgctacatca gctgaccttt tatcgtacgc cccgagtatc
     3121 cggtcgtact ccttaatgtt gcgcaacagt cgtccgggca ttaccctttc cgggcagtgc
     3181 accaacaggt agtccttccc aggcaggaat cccctggtct ccttgatggt cgggatcacc
     3241 aggttctgca tggttcccgg cgggatggtg gattcgatgg agaggagcgc gccaggcttc
     3301 atgttggcgg cgatggtcgc caccgcgctc ttcaggaact tgaggttcgg gatcttgttc
     3361 tcatccaccg gtgaatccac gctaacgaaa acggcgtccg cttccttcag gacggaaggg
     3421 tccagcgagg cggataacaa tcctttggcg tgaacttcgg ccagcagctc gctcagtccc
     3481 ggctcgtcac cctcgatggg attgattccc gagtcgatct tctccacctt ggtggccacg
     3541 atgtcgtgac ctatggtcct tattccagtg gaggcgaacg agcaggccaa tggcagaccc
     3601 acgtatccga gtccgaccac ggccacgatc tttccatgca tgaaggtgaa tcaatggacc
     3661 tgattaaaag acctttgact gttgaggcgg ttcgggatca cttcttcttg accggtttgg
     3721 ccgggttccc gaccacggtg gctccggccg gaacgtcctt ggtgaccacc gcccccgcgc
     3781 cgacggtggc gttctcgccg atggtgacgc cacagacaat gaccgctccg gcgccgacgg
     3841 acgcgccttt cttgaccacg gtcggcgtga tgctccaatc accgacagca tgcgggtgca
     3901 ggtcgttggt gaacgttgcc cgggggccaa tgaaaacctc gtcctcgatg gtcacaccgg
     3961 acggaatgaa ggcgaaagcc tccaccttgc agcggtcacc tatggttacg ccgcgttgga
     4021 tctccacgaa ggcggctatg cggcattctt tgccgatctt gcagccatac aggttgacgt
     4081 aatcacggat gatggtctcg tcacctatct ggcagtcgat aatggagtaa tatttggcca
     4141 tcaacttcat ggtagttcct ctaaagggac atcattgatt aaataatcat ttataacgct
     4201 cttatcaagt atcctccatc ggtctactgg cctttgaaaa aatgatcacg gggaggaaag
     4261 cttccatact tggaacgttc cgaggagtcg ggagagcaag gttcgatcct accgtcagaa
     4321 caagatttcg ttctccaaaa aggaaacgat gcgctcggac acctttgaat caccgtagct
     4381 cgtcctcctc tgggcggtcg gggcatctct ggacacggcc tctacgattc tctcccgatg
     4441 ggctccggtg agcacgttcc aaccgtcctc cagtgtctcc acccattccg tctcgtccct
     4501 caccgtcacg cacggcactc cgaagaagta agcctccttc tgcaccccgc cggagtcggt
     4561 cattatctta taggcgttct tttccaaggc ggtgaaggcc atgaagttct tgggttcggt
     4621 gagcacgatg ttcttggcct cctccaacac cctgagcatg tcccagccgg ccaggttctt
     4681 cctggtccgg gggtgcagcg gcaggacgaa ggtctcaacg gattcgagca tggccccgat
     4741 gatctcctcc atgttcctcc ggtcgtcagc gttctcctgg cggtggatgg tgcagaggat
     4801 gtacccaccc ttctccactc ccagttcgcc gagcacctca tccttgatac ggggtccgac
     4861 gtccagcagg acctcggtca tggtgtcgcc cactacatgc acaccgctgg tcacgccctc
     4921 gtggataaga tggtctacgg acacctggct gggnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5041 nnnnnnnnnn nnntgcagga tgatgtgctg gtgtctcttg gacaccgccc tatgcaccgg
     5101 tgagaccttg atgaactggg gtcgggcgcc gacgattgac agaacgttca tgcatcacgg
     5161 aaatactttt atccatttat cattggttgc tacgcgttca tggatggaat gatgaacggc
     5221 cttaagggac tatgtggggg gtctttccga cccggctcga cagcaccctc tccacgatgt
     5281 catccagggc cttcatattg ttctccgagg tgacttcgga cgctgcctga tccgatcttg
     5341 ccttcatctg ggcgatgctt tcggcgtcca gcgagttcaa tgcctcagcc atggaccggg
     5401 gctcgaagtc cttggccaca atgccgcagc catacttctt aacatagtac gccatctccg
     5461 gagaggggcc gatggccacg gccaacctgg cctggatgaa ctcgaacagc ttgttgggca
     5521 agctgtgcag ctggttgaag ttgtgcggct ggattatgtg cagaccgatg tcgtagccgt
     5581 tggtgtgggg gactatgtcg gccataggta cgggggggat cagccggacg ttctccctat
     5641 cctggaccat ccgctgcagc ttccggtaat acttttgatt ggtggggacc agcatgaggt
     5701 ccagggagaa cctatggtct gtcaggtcca tcacttcgat catgctctcg atatgccggg
     5761 acggattagc tatgccgtgg gcgatgatcc tgatattatc gggttcgacc ggattgggaa
     5821 tcatgtcccg gtactcggtc gagttggtga tgacgatggg gtcgatccca tagaccttgt
     5881 ggtactcctc ggcgatgccc gggcagaccg tgatggtgcc agcacatcca gggaggtagc
     5941 gctcgcacat ctggacccta tacttctgtt ccagaaacct ccacatcgcc cggtcctcgt
     6001 actgtcgggg ggagtattcg tgcgcatcgt ggatgaccgg ggtgggaccg aaggagaagg
     6061 ccaatggcag cgagtcattg tcgttggcca gaacgagatc gatatcctca gggtggacat
     6121 ggtccagcag gtcggaggcg tcgaacgatc tctcatagta tctgtcgaac ctgccggtct
     6181 tcagccacat agcccgggcc agcttagcgg gaaggttccg gtggaccccg atcctataga
     6241 aaggcacacc gtcgatttca ggtccggcga aacccgcggt catcacctta taattctttc
     6301 tgagatggat gatctggcga tatacccgtg ggtcgttctt catgtcggag aacgaaatga
     6361 tcagaatcct ttccttcatc gggccaccag atgtgatatc tccccgaccg cgatggtata
     6421 ataaataaga gcgtaccgcc ggtccattgg gctcattgac catttcgaaa agatcttgtt
     6481 cgtgcgcggt cgatgagaga cgtatggagt tttatttccg atcattcttc cttcaacact
     6541 cgttcgtagc attctatata ccgtccggcc acccattccc aggtgaactc caggctggtt
     6601 tcgtagcatt ccatcatcat gcgcttcata cgctcccggt ccccaatgag ctgcaggacc
     6661 tggtcccgta tctcctcgaa cgtggaatcc tttccaaaga tgagcgagca cttttcgatg
     6721 acggcacggt cgtcaagatt ggcctttacc accggaatgg ttccggaaag caggttctca
     6781 aagaccttgt tgggggaact cgggcgtgat tccgaccaca ccgggctatc ggagcgcatg
     6841 aacaggaatc ccaaatggga actttgggtg agccgtatga catcctggta agggatctca
     6901 cccaggtacc gcatgcgttc cccgaattcg gagatcatgg aatcgacaag ggactgcacc
     6961 tggggatcgt acatccgtcc ggcgacggtg aaacggacgc gcgggtccga ttccatcaag
     7021 gaacgaagca cccggaactg cagctcgatg tctctatcga agctcaggtt cagcgagcca
     7081 aagtaaacgg agtcaatgat gctgtccggc cctaggtccc gcaccttcct ttcgaccgcc
     7141 tccttgttgg aaaattggcc cggagggtag ttggggatga tggtcacagg ctttccggcg
     7201 aacacccctg gcaaatcatg gtagttcctg ctgacgaata tgacttccgt cacatgttta
     7261 ccgtaccatt tttcatacat gcccgcaaca gaaaaaccca gacggttctt ccaggcctca
     7321 aagtactcgt gacggtcata gataatgggg gcgtcgccga acctcttgga caacttacct
     7381 gccaatccta acaggtaagg gtcgtgcaca tgaaggatga tctggtcgcc attcttcacg
     7441 aactcgctcc tcagcattct ctccagacgg gaaattcccc agcccaacat ggttcgcagg
     7501 tcgaagagcg cgccgttgag gtaatggttc ttggaaggtg ataaattgaa ggtcacggcg
     7561 tccttggttg tcttaggtga aggtcggtca ggatagaagt tgaaattgat tcgaaaaagt
     7621 tcatagctct cccggaccgt cgcgatgtgc ttggatatcc tattatcatc gaactgatga
     7681 aggtctaaca ccacgacctt gatgctcacg atcaggcaga ttcgaatgca ttgcttatct
     7741 attttgggcc tatagctctc gatcatttta tccaacgaga ccatccgcta tgtgaaggtt
     7801 cggtgttcaa gaagaactgg aaagattatt gaaggaatat aggggcacga cctcatctcg
     7861 acccagtcaa aaccgggtag cctggatacg gggttgatgg ataccgatcc cggttcacgt
     7921 tccgataaag gtggtcacac cgaaggtcat gatattagct cctcacactg acgatgccga
     7981 actgggttac ggaggcacca taagtaaaat gacaaaggat ggaaatgagt tatgctggat
     8041 ggttttttcc accgccgagg gctctcttcc ccttggcatg tcgaggggca ctctgaggac
     8101 cgagttcctg tccgtggtta aggacggggg gctggatgat gatcatcgca agatatttga
     8161 tttcaaggtt cgtaacctcc atcagtatct tcaggagata ttggaggaac tggtcaggac
     8221 caagaacatg ttccgtccgg acctggtgat cggaccatct ctcaacgacc ttcaccagga
     8281 ccatcaggtg tttgccctag aggtgaccag ggcgttcaag ataaaagaga cggcctttag
     8341 gttgtcggtc ttgaccttag catcctcctt gaccgcctca attgatatat cgcggtcggc
     8401 gaggtcctga aaggaaacgg tcaggcgaag atttttgagc aatttacgtg actcatcctc
     8461 ggccatgctc ttaagcaggg agttggtgac actctcccgg gtcccctcca tcctctctgg
     8521 tgacctggtc ttaaggacca catcgtaacc ggccttcaat agcacggtgc agatctgcac
     8581 acccattatc gcgtgcccaa aacgccaatt cgggcgttcg taccgatggc cgcttcagtt
     8641 ccggatgtcc cgcacatttg atcgaaccat agaaagtacg ttaagtgatt tatccatatt
     8701 gaaccactta atcacttgaa ggtccgggag agctcctcga tatgtttccg agaagaggcg
     8761 ccgacgatca cgccggacag tccctgcaat cctctcaaat attcgctgga taccgccaac
     8821 ggaatggagc cgccgcccat tatgttcatg gcgtagatgt ccagatcgct ggtgttcacc
     8881 accttttcca cgctctcctt ggaggggttc atgtcgaacc cataggggtt gatcggagtg
     8941 atcacggtcc ccgggcgcaa cccccactct ttgagctgcc caaccatcat ctccaggttg
     9001 agggtgatca gtcccgcgtt gaccccgaac ctcctccgca cgctgtcaaa ataatcgccg
     9061 aaggccgatt ccccgtcaaa ggagagcaac aggtcgctta ccacgttgtg catcagcacc
     9121 ccagaaatat cgtactgaga gtatttggag gtctccaggt ccagggcctt gacgcccatg
     9181 cccatgtagt ccgagcgtat cagcttggga agcagttgga acggggtggc gagaagcgag
     9241 gtcactggag cgtcggtgat tatctcctta acgattccct tgatccccga ctcggccatg
     9301 cgtcgcacgt agccgctgac gtatgggacc tgtaaaagga acttcatgtc gaacgtccca
     9361 tccttctcgt aaaggtccat gaaagccctc atccggggat gcgcctcgat gaccatggta
     9421 tcgaaaccgt tttcattggc gatcttgacg acctccagga tcttggaggg gtcggagaac
     9481 aaccggtcct tctcagaggc gctgctctca gaggtatggg atatccccag gaactgattg
     9541 tgtcccaata tcaacttcat cagatcgacc tcggtgcgac tcggtcactg gctttcttga
     9601 tcgatgaata accggcctcg atgacgtagt tggttttagc cgcttcggta aaatcacaga
     9661 tggtgggcgt gttctttaag atggaatcga tgatgtgcat atcctcgcga gtgtattccg
     9721 gcccccctat gttgatatgg acgcccttct cgatatgctg cttgtagata gttcgttctc
     9781 gtttctcagg aacggtctcc ctatcgtcga tgacctcgat gtacttctcg cagaccctta
     9841 tgcgcccgaa ctcggtcctt atgtccatca tcatctccgg caatctaaac ccgggttctg
     9901 accacgagac gtctaggctt ccagacaaac cgttccgtag ttccaggtcc acatgggtgc
     9961 tggtctccac cccggacggc atggtcgcca acgccgttgc ggatacatat tgaacatcgc
    10021 ccagaagata atgcaccatg tcaaaggcgt gcgatcccag gtccatgagc accccgccgc
    10081 cgctcttctt cgggtcgtac tgccatccag tggactcatc gatgttctgg gtgacgaaca
    10141 tgtgtgagct gaatgattta acctttccga gctgttcgat ctccagcatg ctcttggcca
    10201 tttggtaggt ggccatgaat cgccggcaat agccgacgca tgtggtggtc ttttcgctgg
    10261 caacggccag ctcaaggctc tggtccccgt tcagggccaa tggtttctcc atgaagacgg
    10321 ctataccttt cttcagggcg gtcatggcca tgcggtgatg caggaacact ggcgtggtga
    10381 ccactacaag gtcgagttcc gcggactcca gcatgtggtt gaagtcatcg tacatcgtcg
    10441 ccttgggcag ggccgagcgg agcaatctca ggttcaaggg agcggtgtcg catatcgcga
    10501 ccaaactgga gcccgggatc ttattgaaaa ggcaggtgtg caatataccc atcttaccgg
    10561 ccccgattat gcccgttctg accttatcca tgggatttct tcctgttctc cagtcgatgc
    10621 cttacataag ataaaagggt tcgccgagat ggtgctcttc ggtcattcca tccgatcaga
    10681 taaaagatat ggaataacca ttgcccgcct cgaccaccac catgctgttg aacatggtga
    10741 cgtacgtagg aattccgctc agcctctcga tcactccagg ctgaggcacc agcgggatgc
    10801 cgtaaccctg tccgcatgat attatcgcca cctccggcgt ggaggcgtta aggaattcag
    10861 aggaagttcc ggagttcact ccatgatgcg acacctgtaa tacgtccacg tccagatcga
    10921 agccgaggtc catcattgcc gcctcagcaa cccattcaat gtccgccgtg aacaggaagc
    10981 tcgtttcgcg atagtccatc cgaatgacga tgcaactgtc atttatccta gtggcgttcg
    11041 aatctatcca catcacccgg aacgtaacct cgtccgagat ctccagataa tcgcccgggg
    11101 agatcgtggt atcgttgtac accgggcacc cctcggcgac cgtggcgttc atgaccgagg
    11161 accaaagcat cggctccagg ttgtccgagt tacctggcat gtagatgcgt tccacttcac
    11221 acatgttaag cacttcaacg gcgaaagaga cgtggtcggg gtgcgggtgg gtaattatga
    11281 aagcgtcgat cttggtgacg ttgagatcat ccaggaatac cgcggtggat ttgaaggtgt
    11341 caaaactgcc tgcatctatc aggatgttct tttcgtctgg ggtagttatc aaaatagata
    11401 ggccatggcc gatattgagg aagcggactg tgagatcgac gtcctccccc cccccagtaa
    11461 tatttttaac ataccaaaat ccgaaaactg aggtggtgat tatcagcgag gaaatgagga
    11521 tggctaacac tgtccgggac ttgcaggaac tcagcatcag cgttaataag cagtcactca
    11581 taaataatca attagatggc ctcataaggt ggaaaaacaa aattcgtgac gccccgaaac
    11641 gatgacctct cgcgttttga acgccaggct tgccatcgtc ccggtgacgt cactgcgggc
    11701 tctcccgatc ccgttgagcc gtttataacg tgatgttatt taaaccagtt gcgagtcgcg
    11761 ttttccctcg ccgagggcga tcttgccgtt cttcatagct catccaaccg ccggcagtcc
    11821 cgtggtagtt ggtgaagagc tcataatgct attataaaac gatgcacttc gttcaagtcc
    11881 aggcggcact gtgccctatg cgggtctgga tttccttttt tttaaaaaaa ctagattata
    11941 atattatata ctgaacgcaa tccgttctta ggttgatatt ttgatgaatg aaaaaaataa
    12001 agatcgcagg atataccaga cggtcctagc gatattgatc atctcttgca tggtgctctc
    12061 tggaaccctg ttcctgacga acgacgcttc ggcggctccc atcggggcac cgctaccacc
    12121 gagcaatctg accgccgtcg gagactacgg cgagatcacc ctgagatggc aagctccaag
    12181 tggcagcata accgcgaaat catatgtcgt ctaccgttct tactatggtg gtatgagcgt
    12241 gatcggtggt accagcaaca ccttcttcgt cgatacgcag gtcagcaacg gtcaaggctt
    12301 ctcttaccag gtcgccgcgg tgagcggtac gaacgagagc gacaaatctt ccatggccta
    12361 cgccagagca ggctcggtcc ctctcgcacc cttcaatctg gtaggtcagg gttacgatga
    12421 gcgtgccttc ctgtcatggg ctgctcccga caatggcggt ttctcgatcc aaagctataa
    12481 tatttaccgg tcgaacaaca gcttgagcta ctatctgatc ggaaatgcct atggaaactc
    12541 gtataacgat tacgagctca ccaacggcca cgattatcgt tatcaggtgg cggcggtgaa
    12601 cgagctgggg gtcggccctc gctcctcgat cgtgaccgtg acaccaatga ccactccctc
    12661 caaccccggc gggttaaggg tttactatga tgatgccagc gcttacctgg tgtggaacga
    12721 gccattggac gacggtggcg cggagataac tgagtaccgg atacagtgtc gggtacagaa
    12781 ccgggtctgg tcgatcgaga ccggaagcgc ggtgaccgag tactggatca aggacctggt
    12841 gaacggctac acctacgagt tcacggtggc cgctgtgaac gctgccggag tggggggtta
    12901 cacgttgtcg gtcagtagcg acgtcttcac tgttccgacc ccggtcacca accttaaagc
    12961 ctacgctgga gaggagaacg taatgcttac ctggaacctt ccgggatatg acggcggttc
    13021 gtccgtgacc catttcgccg tctaccgttc cacatccgcc ggcggcggat attcgctgat
    13081 cggcattacc aacgtcaccg cctatgccga cctggagttg gatggcggga ccaagtacta
    13141 ctatcgggtg gcctcgggca acgccgtcgg cctgggagag atgagcgacc aggtctccgc
    13201 ggaaccttcc aacccgccgg tgccctgggt agcggtgata atcgtcgccg ccgtcctggc
    13261 ggccatggtg gtcggggtgg tcctgcagtg gaggaagaag gcctgagcgt ccccaaagag
    13321 cgataatgaa accacttccc tttctctttt tatcatcaga acgtgttgta atagttttat
    13381 aattctatat acattttaat atgggatggc ataggttata atatccatca tctaaatccc
    13441 aggctatggc cagcaaactt cttttcattc tgatatgctg cgtcgtgacc ttgttcctgc
    13501 tgcttccgac gatcgctcag ccgaccgttg gcgagacggg attcgatctg gatggttcga
    13561 tcggacggtc gtccggtgtg gtcatacccc aacctatggt cctgaccgtt gccaacatcg
    13621 cgggaaatcc tgagagcttg gatcccgccg tcgattttga gacggtggga ggagaggtaa
    13681 ttcagaacgt gtatgagacg ctgcatcgcc aggtccaaag tctgtccggc cgccatttag
    13741 atgaagaagt agtcgaccct gtcgatcaac caatcagtgt cctcggtcca ggcgatatcc
    13801 tgtaaacgca aggaaaagat caatctgcgc ggtactcccc gctctctatc ctcttcaacc
    13861 acgtttcgtt cgagagatac caatctatcg tgtctctcat ccctttctcg aacctcacgg
    13921 ccggagacca tcctaattcc cgcgagatct ttccgttgtc tatggcgtaa cgaagatcgt
    13981 gcccctttcg gtccttgacg aacgatatga ggtcctccgg cttccctaac tgcctcagga
    14041 tgagcttgac gatgtctatg ttgcgccgtt cgcaattacc gccgatgttg tagacctctc
    14101 ctaccttgcc tttgctgagg atggcgtcta tggcgctgca gtggtccgac acgtgcagcc
    14161 aatcacgaac gttctcccct ttaccgtaca ctggcagctt ctcgttgcgc aacgccaaaa
    14221 ctatcattct agggatgagc ttctccggga actgatacgg cccgtagttg ttggagcagc
    14281 gtgatatggt tataggaaca ttgaacgtgc gatagtaggc gtgacacagc aggtcggcag
    14341 aggccttgct cgccgagtac ggggaggacg gcactatcgg atactcctcg gtgaacttca
    14401 ggtccttgcg ttccaacgga aggtcgccgt acacctcgtc cgtcgatacc tgatgaaaac
    14461 gctctattcc gaactccctg caggcgtcca agaggttctg cgtgcctagc acgttagttc
    14521 tcaggaatga tgacggatct tcaatggaac ggtcgacatg cgattcggcg gcgaagtgca
    14581 cgaccctatc gaaatgttcc ttcttgaaga ggtcccggac gaaggagcgg tcgtttatgt
    14641 ccccacggac gaaggtgaag ttgtcctttc cgatgacgcc gtccagattg tccaggttac
    14701 cagcgtacgt cagaaggtcc aggcagacga tgtcattgtt accgttgata ttggagcgaa
    14761 tgtagttcgc cccgatgaaa ccggctccgc cggtgaccag taatttcatt acctaccctc
    14821 ccagatgaaa tcggttcccc gttccctcaa agaaggcgcc ttgaggtcct tatcagaaag
    14881 taacggctcg gaaacgcccc attctactcc gatctccgaa tcgtcgtaac ggatattgcg
    14941 atcgtgctcg tagctgtaga agttgtctac cttgtactga acctcgcagc cgtcctccaa
    15001 ggtcaggaag ccgtgcgcga agcccttggg gatgaacagc tgcttcttgt tgtcggcgct
    15061 gagcacgagg ccgaaccatt tggcgtagtt aggtgagccg tgacggatgt ctacggcgac
    15121 atcaagaacg cttcctctgg tgcaacgaac gagcttggac tgatcgaacg gcggcgcctg
    15181 gtagtgcagc ccccggatga ctcccttcct ttccgagtag gagtgattgt cctgcacgaa
    15241 ctccacgtct attccttgcg gtctgacgtt acgaacggaa tagctttcaa agaaccagcc
    15301 gcgggagtcc tggaagacct tcggttctat gacgatcagt tcgggcagcg tagttgcttt
    15361 cgtcgtaagc tcaccgccga accgggtcct tgagcatccg gtcgaggtac ttgccgtagt
    15421 cgttgttctt gttcc
//
LOCUS       DAOPZI010000033        14194 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_4662_length_14194_cov_8.034868, whole genome shotgun sequence.
ACCESSION   DAOPZI010000033 DAOPZI010000000
VERSION     DAOPZI010000033.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 14194)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 14194)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14194
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4662_length_14194_cov_8.034868"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..1839)
                     /locus_tag="PKM11_06750"
     CDS             complement(<1..1839)
                     /locus_tag="PKM11_06750"
                     /inference="COORDINATES: protein motif:HMM:TIGR01525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HNX48236.1"
                     /translation="MSVDQGNASEGKRKTASFPVTGMTCATCAGTIADSLNDLEGVLQ
                     ADVNLATERASVTFDPEKVDVAKMRKAVEDAGYGVILNELTLSIGGMSCASCVNTVEE
                     AVGELDGVLSASVNLVTEKLTVRYDPQRVRVAQIKKAVVDAGYEVLEAMTQDLEKEVR
                     EKETLRQKRLLLLSLALAMPTMAIMLVMDFTDLGHHFLMEWGNLIMFALATPVQFIAG
                     YQFYIGAYKAMRNRTANMDTLIAVGTSAAYFYSVAVMFAPGLVTLDHVYFDSSAMIIA
                     LILFGKYLEAKAKGSTSEAIKRLMGLQAKTARVVRDGQEVEMSVDDLDVGDVLIVRPG
                     EKIPTDGVVVDGRSSVDESIITGESLPVSKEDGSEVIGATINGSGLLRIRATKVGKDT
                     ALAQIVKLVEDAQVAKAPIQRLADRVSAVFVPMVISIALVAFFAWYFLGVPAFASGEP
                     AFTFSLTIFITVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGDSLEIAGTVNTV
                     VFDKTGTLTEGRPEVVEIISFNETCPDMFSLVASAEVGSEHPLGEAIVRKAKADGLEL
                     LDIENFEGLAGKGVRASVRGMSIVAGNRGLLEEMGVPLGDREREVAS"
     gene            complement(1884..2255)
                     /locus_tag="PKM11_06755"
     CDS             complement(1884..2255)
                     /locus_tag="PKM11_06755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rid family detoxifying hydrolase"
                     /protein_id="HNX48237.1"
                     /translation="MKEVRVDDAPSSIGPYSQAVVHGDLVFCSGQLGLDPVKGVLVEG
                     AVEQARQALVNLEAVLRGAESSLHKGLRVTLYLTDLSVFPRINEVYAEFFVPPFPART
                     AVQVSALPKGALVEIDIIARR"
     gene            complement(2252..2962)
                     /locus_tag="PKM11_06760"
     CDS             complement(2252..2962)
                     /locus_tag="PKM11_06760"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HNX48238.1"
                     /translation="MSPIIRNGLRSNGLKAIIFDMDGTLIHSTIDFRRMNQGVAETLL
                     RHGLPRDILDSGGKVNESIVRAYSYFKVHSQQGWAEALEKDLNRVSLEVEMTRVEESR
                     EVPGTADALRYLRSKGIRTAVLTRGSRAYTEKALRAAGLEDMFEVVLCRDDHPLTEAK
                     PNPLALRRVYDALGLKGEECLFVGDHDTDLLCAQGAGSPFAAVLTGSFSLDMWNDLRP
                     DVIMDSLAELPILLEGLE"
     gene            3161..>3374
                     /locus_tag="PKM11_06765"
     CDS             3161..>3374
                     /locus_tag="PKM11_06765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48239.1"
                     /translation="MMVRNKVLIGVAALFVISVCALLLGTSVGLLTGIQAIPFIDPHA
                     IPFIDPHAIPFIDPHAIPFIDPHAIPF"
     assembly_gap    3375..3474
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3599..6289)
                     /locus_tag="PKM11_06770"
     CDS             complement(3599..6289)
                     /locus_tag="PKM11_06770"
                     /inference="COORDINATES: protein motif:HMM:NF013776.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HNX48240.1"
                     /translation="MNHIPGRSLLTVKERVFLHLLFQQRFVMDSDSPKSVTQEGVAKA
                     VDVGRNNVAKVLAEMGKEGTVDTFTRHVKGLPSVRKVYFLSAKGSEKAKAIKLDVEST
                     TVDIIDLQGKHIKDEIGRLGNYLPKRYDLLELINGIAQGSIDCRSFHENRMREERRYV
                     DFTDKKPAVRAFFGREREMEVLSGLLTSDTKRMVVINGIPGIGKTTLLAKFAQLVRES
                     TNVFWYKVHEWANLKALLRPLAEFLSQMGRRNLEWYLNQTEAPLVGEATHILETDLKD
                     VSVLLIFDDVHKAEPSVLEFLGALLTIMEGMENVRAVCTARELPTFYSRSAIFRGSVE
                     ELNLEGLDKDSSVQMMRSRGLSPADLEEVFRVTSGHPLFLELIDDPKLALGKNIRIFI
                     EQEVFSRLGVAERKIMSIAAVFRYPVLIDAFFIMEEEIHLAAGVDKIELEGTDYAVSY
                     EAVDSLLSKSIIYESVGRLIGMHDLLREFSLSRLTPRQRRVYHRAAARYYLQDGSAPA
                     RVEGLYHSLMASDMQTAVSIAAGDGRSIINKGYATQFAPLLDRLLRDMGGMERKDLVE
                     ISLLQGEVLYLQGEWDRALEVLRSLRENTSERIDGRMLSEVSRMMGVICLNRADYERA
                     SSLLQEGLDIATRSGDRTTAADILYDMGGVLERRGMNAEALERFEMAKDIASDLSDDL
                     SLGKALYGLGRVRSTLREYEKAIDLKKEALAILERQGDTTMMAKACISIGNDLCALDR
                     NGEGEVYLERSIKLANAVGDLSTMGYALSNLAGCKLNMEDLDGAEELVERCLPIAAKL
                     NDPLMTSTLLFHKGYVRTGRKQWSEARPYFERSLGILRDIDMPSRLGQWLMEVAEMFV
                     QNGEVQEARVLLDEAFDIATKLGHQNLLDKVIEKRERLCA"
     gene            6431..6985
                     /locus_tag="PKM11_06775"
     CDS             6431..6985
                     /locus_tag="PKM11_06775"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX48241.1"
                     /translation="MTGNMDAKVSLLMEGYPRNGFTVFSNYLGKDQGVCITRLHPEYV
                     VEKYGLKNARFHWLSGVKQEGTLSPKSVSTLVKQVKGEIKDGQRKFFLDGLEYLLLWN
                     DMNGIVASLKEIEKEMGNVDANMIVSIDPLTFEEKDLRKLKESFPEMAKISAGSPQNG
                     VDEPADKGRINADLLVSRGLTASP"
     gene            complement(6885..7424)
                     /locus_tag="PKM11_06780"
     CDS             complement(6885..7424)
                     /locus_tag="PKM11_06780"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX48242.1"
                     /translation="MRQAYRMNADIDLCGKFYSIDVHSEYGLFSLDHGRIYMVINERL
                     DKTLSLINGLASAGKEIICVSRMHPDLLRERYPLQDIRGVWLSETGNGPRLSPDHLDK
                     IVEEITSFVSCHKNAAAVLDGLEYISLFTDFRTLNIFLEELNDVVMATRSILLIPIDP
                     RLFDPCQLARLRRFAEILH"
     gene            complement(7529..8833)
                     /locus_tag="PKM11_06785"
     CDS             complement(7529..8833)
                     /locus_tag="PKM11_06785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrpB-like pyridoxal phosphate-dependent enzyme"
                     /protein_id="HNX48243.1"
                     /translation="MRHDVKFSLDIDDIPKRWYNIAADSPVPLPPPHNPVTNEPMDPK
                     ALEAIFPRNLIEQEVSQERYIDIPEEVRDAYVMLNRPSPLVRAVRLEKLLKTPAKIYY
                     KREDLSPCGSHKPNTAVPQAYYNMKAGTEHITTETGAGQWGMSLALACSMFDISCKVF
                     MTCSSYDSKPYRRIAMETYGAKVYSSPSGETKFGREIKAKFPDTPGSLGIAISEAVEM
                     AVSEKNTKYSLGSVLNHVMLHQTVIGQELMTQLEMADVVPDHMVACVGGGSNFSGFSF
                     PMLAKKIQGKIDTDFVAAEPASVPSLSKGEYRYDFGDTAGMTPLLKMYTLGHDFIPSA
                     IHAGGLRYHGMAPTVSLMKDLGYVRAVPVEQKATFEAGIMFANAEGVIPAPESTHAIA
                     ASIDLAMEAKRKNEEKVIVFNLSGHGLLDMTAYEKYLSGKMV"
     gene            9011..9730
                     /locus_tag="PKM11_06790"
     CDS             9011..9730
                     /locus_tag="PKM11_06790"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX48244.1"
                     /translation="MAIISCQDVVKTYITGNIRVEALKGISLGIEKGEMVAVMGPSGC
                     GKTTLLNCLSGIDDITSGSVQIEDTELTGMDDNAKTRFRARRMGFIFQFYNLLPVLSA
                     VENVELPLLISGESPKLARESALSLLETVGLKDRAMLRPASLSGGERQRVTIARALVN
                     KPALVWADEPTGDLDKRTADEVVALMRQLNKDNQQTFVIVTHDPEVGMKCDRIIHMRD
                     GEIVDEDGRVTTVCQDIIERG"
     gene            9747..12725
                     /locus_tag="PKM11_06795"
     CDS             9747..12725
                     /locus_tag="PKM11_06795"
                     /inference="COORDINATES: protein motif:HMM:NF024116.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HNX48245.1"
                     /translation="MIALRTVIVLALLALPWLFLGTAISLVIDIGLIVSVILLDAWKN
                     HLVSVMAVRYALRRPATTALVIGGLMVGTAIVSATFAVSDTMDNLIVGQVTEGLGEVD
                     MVIAAEFASSYIFINESKLDAVSSNLTALNEVVHIEPVASESAVVLDARTGLSSLSNT
                     ALGFSDEGASKFGGFVYEGTALEVSPSSGQAYLPQGLAMDLDAAEGDLIMLLRGNSSL
                     ALTVMKIVADERLGAYSLEGGGFSSSFTVFVNKTDLQMWTGNPGSSNLLFVSLDRDMP
                     IDRQKIESVLSSSEIDGLKIVQDRAEILEEGRDGLSSFISLFFVFGSFSVIAGMALVL
                     NIFTMLAEERKSEMGITRAVGLPRAGLRRLFVYEGVVYATFASALGTLLGLLVAYLII
                     LSVSGVFGFTGIDISSYFTFTPEGLAYSYLIGFVITMGTVYFATLRVSRMNIVRAIRN
                     IPEPPVPAKDRRAFATGLMIMATGVLVTFVGIIMENLGACLSGVSLMTLSTGLLLRRF
                     IGDRLAWNVAGALTMAVWLSKVAGLRLFPYEAEIEMLVLAGLFLLTSALILVMFNSDA
                     IIRFFTAIIRARSSYRAVVRTAISYPLKAKFRTGLSIFIFGLVIFTVTILTMISGVMD
                     YNIPIMVEETSGGFDTIAFTLDPRTVIDTDPWERVNATAGMLDGSNISSMVTMATIGV
                     RVNKTLEGVDGDHRYAEFDVLALGVNRAFYTEGYYPLSDWDRSRFQTEAEVWEGLMDN
                     GTLVVIDGGLAGAAGGFMQFGGGESVVLNDSFAVVAWDGTRTNVTVVGVMKQSALGGV
                     FVNEEAVYSSFKALGVNRLLVSYAEGLDPARQSVLLEREFLDAGLSTISVKALAEEIT
                     ASVDSIFTLFRAFLAMGLIIGIVGLGIITIRSIYERRLEIGMMRAIGFTKGMVVANFA
                     LESAFISLLGIVAGSLLGILVGYQLWVESLKEMAFIFVIDWLPILAVGLLAFAATMLS
                     ILPAARGASKVSPAEVLRFE"
     gene            12776..13009
                     /locus_tag="PKM11_06800"
     CDS             12776..13009
                     /locus_tag="PKM11_06800"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48246.1"
                     /translation="MRYGATTRLSPERALEKAQEYFVKLELALQESSDKHALFSSVAG
                     HVLVTVTTEHGTELDIETMGYDAQVKTFLQRIG"
     gene            complement(13006..13872)
                     /locus_tag="PKM11_06805"
     CDS             complement(13006..13872)
                     /locus_tag="PKM11_06805"
                     /inference="COORDINATES: protein motif:HMM:NF013197.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48247.1"
                     /translation="MTNLVGLLEMISDDRISGSSEIYSALLDGLEEALYHRPKVQDWK
                     EFSEGLAKVKRSMAPVQNIAGSIRVLLNAQIPDDQFNGFVRGFLTDLRSRETEANEKI
                     SRNLVKKYRPGKVLTLSYSGTVVNSIYSMPKSVEISVAESLPMGEGFLTCHKLLEKGY
                     PATLFKDSLMATEVQKVDLVLVGADGVSPEGVVNKVGTMMAALAAKKNKKPFVVVCST
                     SKLIPVLELDPMENEEVVNEVKVREAVFELTPLELVTAVITDEGVLSGAGMKKRLLKD
                     RGNMKVTECQTC"
     gene            complement(13937..>14194)
                     /locus_tag="PKM11_06810"
     CDS             complement(13937..>14194)
                     /locus_tag="PKM11_06810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48248.1"
                     /translation="IPPMNLESFELKIKEFLKENESPIVVLNGVDVLYSWNGLRPVID
                     SLKRARGGLGNAEFFISLDPNEQNPGYVGALERISDEVVCT"
BASE COUNT         2853 a         4144 c         3989 g         3108 t
ORIGIN      
        1 ggaggctacc tccctctctc tatctccaag aggcaccccc atctcctcga ggagaccgcg
       61 gttgcccgcc acgatgctca tacctctcac agaggccctt acgccctttc cggcgagtcc
      121 ctcgaagttc tcgatgtcga gcagctccaa accgtccgct ttggccttgc ggacgatcgc
      181 ctcacctagt ggatgctccg aaccgacctc cgcgctcgcc acgagcgaga acatgtccgg
      241 gcaggtctcg ttgaaagaaa tgatctccac gacctcggga cggccctctg tcagcgtccc
      301 ggtcttgtcg aagaccacgg tgttcaccgt tcccgctatc tccagggaat ccccgccctt
      361 gatcagtatg ccgttctcag cgcccttgcc ggtgccgacc atgatggccg tcggagtggc
      421 cagacccagg gcgcacgggc aggcgatcac cagcacggtg atgaatatgg tgagcgagaa
      481 ggtgaaggcc ggttcaccgg aagcgaaggc cggaactcct aagaaatacc aggcgaagaa
      541 cgccaccaag gcgatggata tcaccatcgg cacgaatacc gccgagacgc ggtctgccag
      601 cctctggatg ggggccttgg ccacctgggc atcctccacc aatttcacga tctgcgccag
      661 ggcggtgtcc ttccccacct tggtggccct gatccgcaga aggccgctac cattgatggt
      721 agctccgatg acctccgagc catcctcttt ggacaccggc aggctttccc cggttatgat
      781 gctctcgtcg acggacgaac ggccgtccac taccacacca tcggtaggta tcttctcccc
      841 aggtcgtacg atcaatacgt cccccacgtc caggtcgtcc acggacatct ctacttcctg
      901 gccatcgcgg accacccggg cggtcttggc ctgcagcccc atcaggcgct ttatggcctc
      961 cgaggtgctc cctttggcct tggcctccag atattttccg aagaggatga gcgcgatgat
     1021 catggccgag ctatcgaaat agacgtgatc gagggtaacc agcccgggag cgaacatcac
     1081 cgccacgctg tagaagtagg cggcggacgt gccgaccgcg atgagcgtgt ccatgttcgc
     1141 cgtgcggttg cgcatcgcct tgtaggctcc gatgtagaac tggtatccgg caatgaactg
     1201 caccggcgtg gccagggcga acattatgag attgccccac tccatgagga agtggtgtcc
     1261 caggtcggtg aagtccatga ccagcatgat ggccatggtg ggcatcgcta gggccaggga
     1321 gagtagcaga agccgtttct gccggagggt ctccttctct cggacctcct tctccaggtc
     1381 ctgggtcatg gcttccagga cctcgtatcc ggcgtcgacc accgccttct tgatctgggc
     1441 gacgcgaact cgctgcggat cgtagcgcac ggtgagcttc tcggtgacca ggttgaccga
     1501 ggccgatagc actccgtcca gttctcccac cgcctcctcg acggtgttga cgcaggaggc
     1561 gcagctcatt ccccctatgg acaaggtcag ttcgttcagt atgacgccat acccggcgtc
     1621 ctccacggcc ttgcgcatct tggccacgtc gaccttctct ggatcgaagg tgaccgaggc
     1681 cctttccgtg gccaggttca catcggcctg caatacgcct tccaggtcgt tcagcgagtc
     1741 ggcgatggta ccagcacagg tggcgcaggt cattcccgtg accggaaacg aagcggtctt
     1801 gcgctttcct tcggaagcat tcccctggtc gacgctcatc ggccgttcta cctagttctt
     1861 cgctgaaata gattttgatt gaactatcgt ctggcgatta tatcgatctc caccaacgcc
     1921 cctttgggca aggcggacac ctggacagcg gtccgagccg gaaaaggcgg gacgaagaac
     1981 tcggcataga cctcgttgat ccgagggaaa acggacaggt cagttaggta cagggtgacc
     2041 ctgagtccct tgtgcagcga gctctccgcc cctctaagca cggcttccaa gtttaccagg
     2101 gcctgtcggg cctgctccac tgcaccttcg acgagaacgc ccttgaccgg gtcgagtccc
     2161 aactgaccgg agcagaacac caggtccccg tggaccacgg cctgggagta cggaccgatg
     2221 gaggacggag catcgtccac ccgcacctcc ttcattccag tccctctagg agaattggca
     2281 gttcggccag gctgtccatg atgacgtccg ggcgcaggtc gttccacata tccaaggaga
     2341 acgaaccggt aagtaccgcg gcgaacgggc ttcccgcgcc ctgggcacag agcaggtccg
     2401 tatcgtggtc cccgacgaac aggcattcct cccctttcag ccccagggca tcgtaaaccc
     2461 tgcgcaacgc cagggggttc ggcttggcct cggtgagcgg gtggtcgtcc cgacagagga
     2521 ccacttcgaa catgtcttcc aatccagcgg cccgcagcgc cttctcggtg taggccctgc
     2581 ttcctctggt cagcactgcg gtgcggatgc ccttcgaccg cagatatctc aaggcatcgg
     2641 cggtcccggg gacctcccgg ctctcctcca ccctggtcat ctcaacctcc aaggaaaccc
     2701 ggttgaggtc cttttccaaa gcctctgccc agccctgctg actgtgaacc ttgaagtagg
     2761 agtaggcccg cacgatgctc tcgttgactt ttccgccgga atccagaatg tcccggggaa
     2821 gtccgtgtcg cagaagcgtt tcggccactc cctggttcat cctccggaag tcgatggtgc
     2881 tatgtatcag cgtcccgtcc atgtcaaata tgatcgcctt aagtccattg gaacgaaggc
     2941 cgttgcgtat gatcgggctc atggtcgggg tgcatgaggg tacgttgata gttaattgtt
     3001 ttgcccatct ggaaaatgtt gtaatgaatg agtgatccag cattctatat ttatcgtcgt
     3061 ccctgattgt aagtataaaa tcttattggt agcatgctca aatacccatt ttatatgcac
     3121 aagtcgaaac agggttcata ataatacgag gttgttgttt atgatggtga ggaacaaagt
     3181 actgatcggg gtggcggccc tgttcgtgat ctccgtctgc gcattgcttc taggaacctc
     3241 ggtcggccta ttgaccggaa tacaggctat tccgttcatc gacccgcatg ccataccgtt
     3301 catagaccca catgcgatcc cgttcatcga cccgcatgcc ataccgttca tagacccaca
     3361 tgcgatcccg ttcannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnccgttc
     3481 atcgacccgc atgccatacc gttcatagac ccacatgcga tcccgttcat cgacccgcat
     3541 gccataccgt tcatagaccc acacgcagtg tctatctaag accgataaaa tatgcgcctc
     3601 aggcgcataa cctttccctt ttttctatta ccttatccag caaattttga tgacctagct
     3661 tggtggctat atcgaacgct tcgtccaaga ggacccgcgc ttcctgcacc tcgccgttct
     3721 gcacgaacat ctccgccacc tccatcagcc attggcccag tcgggaaggc atgtcgatgt
     3781 ccctcaaaat acccaaggac ctctcgaagt aagggcgggc ttcgctccat tgcttgcgcc
     3841 cggttctaac gtatccctta tggaagagca acgtggaggt catgagaggg tcgttcaact
     3901 ttgccgcgat gggtagacac cgttccacca gctcctccgc cccgtccagg tcttccatgt
     3961 tcagcttgca tcccgccagg ttggatagtg cgtatcccat ggtgctgagg tcgccgaccg
     4021 cgttggctag ctttatcgac ctttccagat agacctcgcc ctcgccgttc cggtccaggg
     4081 cgcagaggtc gttgccaatg ctgatgcagg ccttggccat catggtggtg tccccctggc
     4141 gctccaatat cgccaacgcc tccttcttga ggtcgatggc cttctcgtat tccctcaaag
     4201 tggaccggac ccgacccagg ccatacagcg ccttgcccag ggataggtcg tccgagaggt
     4261 ccgaggctat gtccttggcc atctcgaagc gctccaaggc ctcggcgttc attcctctcc
     4321 gttccaatac ccctcccatg tcatacagga tatcggcggc ggtggtccta tcgccggaac
     4381 gcgtcgctat gtccagacct tcctggagca gggacgacgc cctctcataa tcagcgcggt
     4441 tcaggcagat cacgcccatc attctggaca cttcgctgag catccggccg tcgattcgtt
     4501 cggaggtgtt ctcccgtaac gatctcaaca cctctaacgc ccggtcccac tctccctgaa
     4561 gatagagcac ctctccctgt agtaggctga tctccaccag gtccttgcgt tccatcccgc
     4621 ccatgtcccg gagcaaacgg tccaggaggg gagcgaactg cgtcgcgtaa cctttgttta
     4681 tgatcgaacg tccgtcgccc gcggcgatgg aaacggcagt ctgcatatca ctggccatga
     4741 gcgaatggta cagtccttcc acccgggctg gagcggaacc gtcctgcaga tagtagcggg
     4801 cggcggcacg gtggtacacc cttctctgtc tgggcgtgag tcgcgataat gagaactccc
     4861 ggagcaggtc gtgcatgcct atcagccgac cgaccgattc gtagattatg gatttcgaga
     4921 gcagcgaatc gaccgcctcg tagctgacgg cgtaatcggt cccttccagc tcgatcttgt
     4981 ccacgcccgc ggccaggtgg atctcctcct ccattatgaa gaacgcgtcg atgagcaccg
     5041 ggtaacggaa gaccgcggca atgctcatga tcttgcgttc tgccacgccc aaccgggaga
     5101 acacctcctg ctcgatgaat attctgatgt tctttcccag ggccagctta gggtcgtcta
     5161 tcagctccag gaacagcgga tgcccgctgg tgacccggaa gacctcctcc aggtccgctg
     5221 gggaaagccc ccgcgaacgc atcatctgca cgctgctgtc cttatcaagt ccttcaagat
     5281 tgagctcttc caccgaaccg cggaatatgg cgcttcggga gtagaacgtc ggaagctcgc
     5341 gggcggtgca gaccgcccgt acattttcca ttccctccat tatggtcaac aaggccccca
     5401 ggaactccag cacggaaggt tcggccttgt gcacgtcgtc aaagataagc agcacggaga
     5461 cgtccttgag gtccgtctcc aggatatggg tggcctctcc gaccaatggc gcctcggtct
     5521 ggttcagata ccattccagg ttccggcgtc ccatctgcga aaggaactcg gccaaaggcc
     5581 ggagcagcgc cttcaggttg gcccactcgt gcaccttgta ccagaagacg ttggtgctct
     5641 cccgcaccaa ctgagcgaac ttggccaaca aggtggtctt tccgatccct ggtatgccgt
     5701 ttatgaccac catgcgcttg gtatcggagg tcagtaatcc agacagaacc tccatctccc
     5761 tctcccgtcc gaagaaggcg cgcaccgccg gcttcttgtc ggtaaagtcc acgtaccttc
     5821 tttcctcgcg catgcggttc tcgtggaagc tgcggcagtc tatgcttcct tgggcgatgc
     5881 cgttgatgag ctccagaagg tcatagcgct tcggcaggta attgcccagc cttcctatct
     5941 cgtccttgat gtgcttccct tgcagatcta ttatgtccac cgtggtagac tccacgtcaa
     6001 gcttgatcgc tttcgccttc tctgaaccct tggcgctcaa aaagtagacc ttgcgcacgc
     6061 tcggcaatcc tttcacgtga cgggtgaagg tatcgaccgt accttccttg cccatttccg
     6121 ccaggacctt ggccacgttg ttgcggccca catcaaccgc cttggccaca ccctcctggg
     6181 tgacgctctt cggggaatcg gagtccatga cgaaacgctg ctggaacaga agatgcagga
     6241 agacccgctc cttcacggtg agcagggagc gccccgggat gtggttcacg aggaaaaatc
     6301 actttcccat atcaatagtc ttccacctgc caagcgctac ttgattctca ccgcctgaat
     6361 gtagcatgct caaaactcct ttaaataccg ttaaagccaa gatacggtac aagcaacgga
     6421 ggaatgctga atgacaggaa atatggatgc caaggtctct ctccttatgg aaggctaccc
     6481 acgcaacggg ttcacggtgt tctcgaacta cctgggtaag gaccagggag tgtgcataac
     6541 ccgccttcac cccgaatacg tcgtggagaa gtatggactg aagaacgccc gcttccactg
     6601 gttgagcgga gtgaagcagg aagggacgct gtcgccgaag agcgtgtcca ccctggtgaa
     6661 gcaggtgaag ggcgagatca aggacggtca gcgcaagttc ttcctagacg gtctggagta
     6721 tctgttgctc tggaacgaca tgaacggtat cgtagcctcc ctcaaggaga tcgagaagga
     6781 aatggggaac gtcgatgcca acatgatcgt gtccatagat ccgctcacct tcgaggagaa
     6841 ggacctccgg aagctgaagg agtcctttcc cgaaatggcc aagatcagtg caggatctcc
     6901 gcaaaacggc gtagacgagc cagctgacaa gggtcgaata aacgcggatc tattggtatc
     6961 aagaggattg accgcgtcgc catgaccacg tcgttcagtt cctccaagaa tatgttcaag
     7021 gtccggaagt cggtgaacag ggaaatgtac tccaggccgt ccaggaccgc cgcggcgttc
     7081 ttgtggcagg agacgaagct ggttatctcc tccactattt tatccaaatg atcgggcgag
     7141 aggcgcgggc cgtttccagt ttcgctcagc caaactcccc tgatatcctg cagaggatag
     7201 cgctctcgaa gcaggtccgg atgcatcctg ctcacgcata tgatctcctt tccggcggac
     7261 gctaggccgt tgatgagcga gagggtcttg tccaatcgct cgttgatgac catatagatg
     7321 cgcccgtggt ccaaactgaa caggccgtat tctgaatgga catcaatgga atagaacttc
     7381 ccgcagagat cgatatcggc gttcatgcga taggcctgtc gcacttcccc aagcgctaga
     7441 agggtgaggg cggtaaggat aaataatggt attcgggaaa atgcgacgat ttgaaaattg
     7501 tttgaagggg gcggagcccc caagggtttc agaccatttt cccactgaga tatttctcgt
     7561 aggcggtcat gtccagcagc ccgtgccccg acaggttgaa gacgatgacc ttctcctcgt
     7621 tcttgcgctt cgcttccatg gccaggtcga tggaggcggc gatggcgtgc gtgctctccg
     7681 gtgcggggat tacgccctca gcgttggcga acatgatgcc cgcttcgaag gtggccttct
     7741 gctccaccgg cacggcgcgg acatagccga ggtccttcat caggctcacc gtcggagcca
     7801 ttccatgata gcgcagcccg ccggcgtgta ttgccgacgg tatgaaatca tgaccgaggg
     7861 tgtacatctt caacaggggg gtcatcccgg cagtgtctcc gaagtcatag cggtattcgc
     7921 ccttcgacag cgacgggacg gacgccggct cggcggcgac aaagtcggtg tcgatcttcc
     7981 cctggatctt cttggccagc attgggaacg agaatccgga gaagttgctt cctccgccga
     8041 cgcaggcgac catgtggtcc ggcaccacat cagccatctc cagctgggtc atgagctcct
     8101 gcccgatgac ggtctggtgc agcatgacgt ggttcagcac gctgcccagg ctgtacttgg
     8161 tgttcttctc gctcaccgcc atctcgacag cctcgctgat ggctatgccc aggctgcccg
     8221 gggtatcggg gaacttcgcc ttgatctcgc gaccgaactt ggtctccccg ctgggggagg
     8281 agtagacctt ggcgccatag gtttccatgg ctatgcggcg gtaaggtttc gaatcgtagg
     8341 aggagcaggt catgaacacc ttgcagctga tgtcgaacat cgagcaggcg agggccaagg
     8401 acattcccca ctggccagca ccggtctcgg tggtgatgtg ctcagtcccg gccttcatgt
     8461 tgtagtacgc ttgcggaacg gccgtattgg gcttgtgcga tccacacggg ctgaggtcct
     8521 cccgtttgta gtagatcttg gccggggtct tcagtagctt ttccagtctc accgccctta
     8581 ccaacgggga ggggcggtta agcatcacgt aggcgtcgcg cacctcctcc gggatatcga
     8641 tgtaacgctc ctgggacacc tcctgctcaa taaggttgcg cgggaagatg gcctccaggg
     8701 ccttggggtc catgggctcg ttggtcaccg gattgtgcgg cggtggcaac ggaacggggg
     8761 aatcggccgc gatgttatac cagcgcttgg gaatatcgtc aatgtctagt gagaacttca
     8821 catcatgtct catggaaaat ggggaagatc aagtcaatat atatcattta tggtcatcaa
     8881 tgaacaaata tatgcattta ttcgtagacc aggcacttgt gcgcccttat gatctaagat
     8941 atccgatgat atcatccaac aacgtttaat atcgattgct ggcctattat tctggaatag
     9001 ggggagaagc atggcgatca tcagctgcca ggatgtggtt aagacataca taaccggaaa
     9061 tatccgggtg gaggccctga aaggaatatc tctggggatc gaaaaggggg agatggtagc
     9121 ggtcatgggc ccctccggat gcggcaagac cacgctcctg aactgtctat cgggtataga
     9181 tgatatcact tccgggagcg tgcagatcga ggacacggag ctgactggca tggatgacaa
     9241 tgccaagacc cgctttcggg cccgccgcat gggcttcatc tttcagttct acaaccttct
     9301 tccggtgcta tcggcggtgg agaacgttga gctgccgttg ctgatctcgg gggaatctcc
     9361 caagctggct cgcgagagcg ccctctccct tctggaaacc gttggtctca aggaccgtgc
     9421 catgctccgt cccgcttccc tgtccggagg ggagaggcag agggtgacca tcgcccgagc
     9481 cttggtgaac aagcccgcct tggtctgggc cgacgaaccc accggggatc tggacaagag
     9541 aacggccgac gaggtggtag cgctcatgcg tcagctaaac aaggataacc agcagacctt
     9601 cgtcatcgtc acccatgatc cggaagtggg gatgaagtgc gaccggatca ttcacatgag
     9661 ggacggggag atagtggacg aggacggcag ggtcaccacg gtctgccagg atataatcga
     9721 gaggggctga gggcatgcct cgttctatga tagcactcag gaccgtcata gttctggcgc
     9781 tactggctct gccatggctg ttcctgggaa cggctatctc cctggtcatc gacatcggtc
     9841 tgatcgtctc tgtcatactg ttggacgcct ggaagaacca cttggtctcg gttatggccg
     9901 ttcgctatgc cctgaggcga ccggccacca ccgccctggt catcggaggc ctgatggtgg
     9961 gaacggcgat agtatcggcc accttcgccg tcagcgacac catggacaat ctcatcgtcg
    10021 gtcaggtcac cgagggattg ggcgaggtgg acatggtcat cgccgcggag ttcgcctcct
    10081 cttacatatt catcaacgaa agcaagcttg atgctgtgtc tagtaacctc accgccctga
    10141 acgaggtggt gcacatagag cccgtggcct cggagagcgc ggtcgtcctg gacgctcgta
    10201 caggtctgtc atcgctcagc aataccgctc ttggcttcag cgatgaaggg gcttcgaagt
    10261 tcggtgggtt cgtctatgaa ggaacggcct tggaagtatc tccctcttct gggcaggcct
    10321 acctccctca aggcctggca atggacctgg acgcggcgga gggagacctg atcatgctgc
    10381 tccggggcaa cagctcactg gcactcacgg tcatgaagat agtcgccgac gaacggcttg
    10441 gcgcatacag cctggaaggg ggcggtttct catcttcctt cacggtgttc gttaacaaga
    10501 ccgacctgca gatgtggacc ggtaatcccg gaagcagcaa cctgctcttc gtttcgctgg
    10561 accgggatat gcccatcgat cgtcagaaaa tcgagtcggt cctctcgtcc tcagagatag
    10621 atggtcttaa gatcgttcag gaccgcgccg agattttaga ggagggcagg gacggtcttt
    10681 cctccttcat atccctgttc ttcgtcttcg gttccttttc cgtgatcgcc ggaatggcgt
    10741 tggtgctgaa tatctttact atgctggccg aggagcgcaa atcggaaatg ggcataaccc
    10801 gggcggtcgg gctgccgcgc gcggggttgc gtcgcctctt cgtttacgag ggggtggttt
    10861 atgccacgtt cgcctcggcc ctgggaacgt tgctgggatt gctggtggcc tatttgataa
    10921 tcctctccgt ctccggtgtc tttggcttca ctggcattga catatcgtcc tacttcacct
    10981 tcacgcccga gggactggcc tactcttacc tgataggttt cgtcataacc atgggcaccg
    11041 tgtacttcgc cacattgcgc gtctcgcgca tgaacatcgt acgggcgatc cgcaacatac
    11101 cggaaccgcc ggtcccggcc aaggaccggc gcgccttcgc caccgggctc atgatcatgg
    11161 cgaccggtgt tctggtcaca ttcgtcggga tcataatgga gaacttaggg gcctgcctga
    11221 gcggcgtttc gctgatgacc ctgtccacag gccttcttct ccggcgcttc atcggtgacc
    11281 ggctagcctg gaatgttgcg ggcgccctca ccatggcggt ctggctgagc aaggtggccg
    11341 gcctaagatt gttcccatat gaagcggaga tcgagatgct ggtattggcc ggtctcttcc
    11401 ttctgacctc cgccctcata ctggtcatgt tcaattccga tgccataata cgtttcttca
    11461 cggccatcat ccgagcccgt tcgtcataca gggcggtggt gcgcacggcc atctcctatc
    11521 ccttgaaggc caagttccgc accggcctga gcatattcat cttcgggctg gtcatattca
    11581 cggtcaccat cctcactatg atctccgggg tcatggacta taacatcccg ataatggtgg
    11641 aggagacctc cgggggtttc gacaccatag ccttcaccct tgaccccaga acggtgatcg
    11701 ataccgatcc atgggaaagg gtgaacgcca cggcggggat gttggatgga tcgaacataa
    11761 gcagcatggt caccatggcg accatagggg taagggtcaa caagaccctg gaaggggttg
    11821 acggagacca tcgttacgcg gagttcgacg ttctggcgtt aggcgtcaat cgagcgttct
    11881 acaccgaagg ctattacccg ctgagcgatt gggaccgctc acggttccag accgaggcgg
    11941 aggtttggga gggcctgatg gacaatggga ccctggtggt gatcgacggt ggtctggccg
    12001 gggccgcggg cggcttcatg cagttcggtg gcggggaatc ggtggtcctc aacgacagct
    12061 tcgccgtggt ggcctgggac ggcacccgga ccaatgtcac cgtggtcggc gtgatgaagc
    12121 agagcgccct cggaggcgtt ttcgtcaacg aggaggcggt gtactcgtcc ttcaaggccc
    12181 tgggcgtcaa tcgcctgttg gtgtcctacg ccgaaggact ggacccggca aggcagtccg
    12241 tattgctaga gagggagttc ctggatgccg gcctcagcac catatcagtc aaggccttgg
    12301 cggaggagat aaccgccagc gtggattcca tattcaccct gttcagagcg ttcctggcca
    12361 tgggcctgat aatcggcatc gtaggattgg ggataataac catccgttcc atctacgaaa
    12421 ggagactgga gatcgggatg atgagagcga taggcttcac caagggcatg gttgtcgcga
    12481 acttcgccct ggaatcggca ttcatatcct tgctaggcat cgtggcaggc tctttactgg
    12541 gcatcctagt gggttaccag ctttgggtgg agagcctaaa ggagatggcg ttcatattcg
    12601 tcatcgattg gctcccgata ctggccgtgg ggttgctggc cttcgcagcg accatgctga
    12661 gcatacttcc tgccgcgcga ggggctagca aggtgtcccc agctgaggtg ctgaggttcg
    12721 agtgacctgg tcaggaaaag ttagttatct cccggggata ttcccggggg atagcatgag
    12781 atacggcgcc accaccaggc tgagcccgga aagggccttg gagaaagccc aggaatactt
    12841 tgtgaaactg gagctggccc tacaggagag ttccgataag cacgccctgt tcagcagtgt
    12901 cgccggtcat gttctggtca cggtgaccac ggaacacggc accgagctgg acatcgagac
    12961 catgggatac gatgcccagg tcaagacctt cctgcagcgc atcggctagc aggtctggca
    13021 ctcggtgacc ttcatattgc cgcggtcctt gagcaagcgc ttcttcatcc cagctccgga
    13081 gagaacgccc tcgtcggtga tgaccgcggt gaccagttcc aggggggtaa gctcgaacac
    13141 cgcctccctg accttcactt cgttcaccac ttcctcgttc tccatagggt ccaactccag
    13201 gaccggaatg agcttggagg tggagcacac gacaacgaag ggtttcttgt tcttcttggc
    13261 cgccagggcc gccatcatcg ttcccacctt gttgaccacg ccctccgggc taacgccatc
    13321 ggctccgacc agcaccaggt cgaccttttg aacctcggta gccatcaggg aatccttgaa
    13381 cagggtggca gggtagcctt tctccagtaa tttatgacag gtcaagaagc cctcccccat
    13441 cggaagggat tcggcaacgg atatctcaac gctcttaggc atggaataga tggaattgac
    13501 gaccgtaccc gagtaggaca aggtcaagac cttacccgga cggtattttt tcaccaaatt
    13561 cctggagatc ttttcgttgg cctcggtctc cctggacctg aggtcagtga ggaatcctct
    13621 gacgaagccg ttgaactgat catccggtat ctgagcgttc aagagcaccc ggatcgaacc
    13681 ggcgatgttc tgcaccggcg ccatggaccg cttcaccttg gccagacctt cggagaactc
    13741 cttccaatct tggaccttgg gcctatgata caaggcttct tccagtccat ccaacagtgc
    13801 cgagtatatc tctgaggaac cggagatccg gtcatccgat atcatttcca acagtccgac
    13861 caggttagtc attaacactc cctcaatggt gaaaagaaag ggtgattgaa aaaggatggg
    13921 gttttaactt cgtccgtcag gtgcatacca cttcgtcaga tatgcgctcc aaggcaccca
    13981 cgtacccggg gttctgctcg ttgggatcca ggctgatgaa gaactcggca ttgccaaggc
    14041 caccgcgagc tctcttcaag gagtcgatga ccggtcgtag gccgttccag gagtacagca
    14101 cgtccactcc gttgaggacc acgataggcg actcgttttc cttcaggaac tccttgatct
    14161 tcagctcaaa gctttccagg ttcatcggtg ggat
//
LOCUS       DAOPZI010000034        13833 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_4853_length_13833_cov_10.113587, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000034 DAOPZI010000000
VERSION     DAOPZI010000034.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 13833)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 13833)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13833
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_4853_length_13833_cov_10.113587"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            471..1697
                     /locus_tag="PKM11_06815"
     CDS             471..1697
                     /locus_tag="PKM11_06815"
                     /inference="COORDINATES: protein motif:HMM:NF012531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48249.1"
                     /translation="MINRTGRENKTDRLGMPVQAENYTASRPPGWQGQLGGCGIASCI
                     SLKGEKISGDRIARMLTIMEERENGLGAGYACYGLFPDRRDQYCLQFFFDDEEGKRNA
                     ENFLDGRLEIVHDEKVFTRDRSTISPPYPIVWRYFANVPGHREWRGDRDLGEEDYMVE
                     MVQHVNEKIPKAFCVSSGKDMAVFKGNGYSYEIAELYDLGRYSGTMWLSHSRFPTNSP
                     AWWAGAHPLSLLDWGVCHNGEITSYGVNRKLVEMNGYKCTVLTDTEVVTYLWDLLVRR
                     NGLPVEVAAFVMAPSTFQEISQMPAAERRLAEWLRITYKEAFLNGPFSIIVGRSQPEI
                     ALIALADRKKLRPMIAGLSPDDGVAYCASEESAIRIVEPDARTWAPGAGNPFIAVAGK
                     GVVRKGIEPSFQGVSL"
     gene            1694..3226
                     /locus_tag="PKM11_06820"
     CDS             1694..3226
                     /locus_tag="PKM11_06820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015930 - glutamate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016638 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors [Evidence IEA];
                     GO_process: GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase-related protein"
                     /protein_id="HNX48250.1"
                     /translation="MSETPAMKRLDHRLPERFVPTINYDLCRVCRRCVNDCSYQALEF
                     LESRVVPSGGCVACGRCIAVCPANCIEIRPVPPQFAPHGNWSERSRRSILAQASSGGV
                     LLSSCGADDEHPAIFDDLLLDAAQVTNPSIDPLREPVETVTYLGRRPGKLEVCDGKVM
                     IREDDTPLIRMNMPLMFGHISLGSISYNAQKALFMAAKELNIVAGSGEGGLHPDFYQY
                     ADRICSEVASGRFGIKPEYLKGVAAVEIKIGQGAKPGHGGHLPGEKVTTMISETRMIP
                     LGTDALSPYPHHDIYSIEDLAQLISVLKESTEYRLPVGVKIAAVHNVGAIASGLVRAG
                     ADFLTVDGYKGGTGAAPRVIRDHAGLPVEVAIAAVDRRLTQEGLRNRVTVCAGGGIRS
                     SADMIKALALGADVVMVSTSALVAMGCRVCQQCHRGLCSWGIATQRDDLTNRLDPNVA
                     AARIVRLFNAWNEELKEVLGAMGIDSVESLVGNRDRLRYRGPNPKIAEVMNVKHIGEG
                     WG"
     gene            3226..4056
                     /locus_tag="PKM11_06825"
     CDS             3226..4056
                     /locus_tag="PKM11_06825"
                     /inference="COORDINATES: protein motif:HMM:NF013645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48251.1"
                     /translation="MKDVCKPKGHAHECDCGKDCLSVVGERAVIDLHLSPTQPMHYTT
                     LNCTMRKAMRRGCSSIELKGVMGQRYLASTASDPGLFIAIHGTPGNDLGAFLNGPTIE
                     VFGNAQDMTGNTMNSGKIIVHGNAWDVTGLAARGGQILVKGDTGYRVGIHMKEFGEAR
                     PTLVIGGTAKDYLGEYMAGGTILVLGLGGGAPVGRSLGAGMHGGRIFVRGKVASEQLG
                     PGAAISPLNPEDEKEVLSLLEDFGKAFGTDVPYDAKDFVKVSPSSSRPFSGYYDKTNV
                     "
     gene            complement(4053..4496)
                     /locus_tag="PKM11_06830"
     CDS             complement(4053..4496)
                     /locus_tag="PKM11_06830"
                     /inference="COORDINATES: protein motif:HMM:NF013224.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HNX48252.1"
                     /translation="MPVVDAMNRRILQLLVNDGRMTHNEIAAKLKRSPSTVRDRIKRM
                     EDDGIILGYFAVVNNERMGLKVDAILFANLRPGVPSEELRKLRGVQEVKEVLQVTGPR
                     RIVVRLQARDVNALEQAISAKVIPLGLEDVELRMVTSSANRLPGN"
     gene            complement(4618..5721)
                     /locus_tag="PKM11_06835"
     CDS             complement(4618..5721)
                     /locus_tag="PKM11_06835"
                     /inference="COORDINATES: protein motif:HMM:NF014542.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HNX48253.1"
                     /translation="MQSGDKAPTRFVVLGGYLGAGKTTLAAALGNELRSKHGRSVAII
                     TNDQGNVLVDTEYMKNAGFDVKDVLGGCFCANFGEFVKNARTLVAMGRPDVIIAEPIG
                     TSTAILGSVVSPLRSMYPDEFQVAPFFVIVDGTRAAETLRKPEGFGLGGGKLIPSHQV
                     REAEYVLISKVDRLNEGEVASASDLIRKEVSDAEVIPCSAFSRKNLDRIVDIILSDQV
                     STKEPKDVDQRMFAVEKASMGWFNAHARLVAEGRVDINAFVSSLMRRVATEFAPETIG
                     HVKVMLTSSTASAKMSLVEDRMQVDGLKGGRYFTGEGKIVLNARVSASPNELKKVFEK
                     AIYDTALEAGAKVEEMGEACFSPKPEAPSLFVK"
     gene            complement(5771..6394)
                     /locus_tag="PKM11_06840"
     CDS             complement(5771..6394)
                     /locus_tag="PKM11_06840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48254.1"
                     /translation="MLTADCRIEMAYIDPETYTSIVNHDMRKRILTKLYRSTRDAPIS
                     KQDLADSLGLDYNQLVYQLNNHLRDFWAVKEERKVRGTRMELIEASYPYAVFITIGKD
                     HGIFLVDPLADIYGAVVKVGARCDQCSEEEARRCMEFAQSRFDSEALSEAERGVLAAN
                     NRRSPYRPMDLALLAAIKGMPVGQRCVIDIPCQTCAFLRRTVRIEGL"
     gene            6488..7129
                     /locus_tag="PKM11_06845"
     CDS             6488..7129
                     /locus_tag="PKM11_06845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48255.1"
                     /translation="MVGKKQLCQRCGAPIRRDYEYCNVCGKSTSSVPQARRTSPVNPS
                     KVLPAREAKRKEAKNVDDVVPRRELVIALLAMTCMAPFCTWLSSFGGLIGTSAAFNEA
                     FYGRYVVLLAAMGLLMLLAGNLVPASIPRRGVIAGVGIGTAALTALDYVEIMRYNLSP
                     ESSLIPAMPGVGMYLALGLGIALSLAVLVPKRRSAPYTATRPALRPGSRGSDP"
     gene            complement(7098..8213)
                     /locus_tag="PKM11_06850"
     CDS             complement(7098..8213)
                     /locus_tag="PKM11_06850"
                     /inference="COORDINATES: protein motif:HMM:NF014164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HNX48256.1"
                     /translation="MYDPRMRKLADVLIDHSVRLQKGETVYIEAFDIPSEMVEVLLDK
                     IYEVGGVPMVALRSAKVFRKLLMNADQKTIAQIGEIELEKMKRAQAYIGMRGSYNITE
                     NSDVPADKIDLYMKYWSGPVHTGWRVPKTRWVVLRWPTSSMAQQAQMSTERFEDFYFN
                     TCTLDYPKMSRAMDPLVALMERTDKVRLVSPGTDLTFSIKGMPAVKCEGDRNIPDGEV
                     YTAPIKDSVNGVISYNTRTLYQGKVFDNVVLKFKDGKIFEATSSDTKSQNIIHDTDPG
                     ARYVGEFAIGVNPYINQAMLDTLFDEKIAGSIHFTPGSAYQESDNGNKSTVHWDMVLI
                     QTPEMGGGEMYFDDVLVRKDGRFVIDELKGLNPENLA"
     gene            complement(8304..9098)
                     /locus_tag="PKM11_06855"
     CDS             complement(8304..9098)
                     /locus_tag="PKM11_06855"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HNX48257.1"
                     /translation="MPGEPIIEMRKVSVSKGSATLLRDVDLTIRKGERLVVLGPNGSG
                     KSSLIKTMMGEHRHDTSVPGSYVKLRGSDLWNLFDVRQAFGLVSADLQVDLSRDMDCL
                     EAVLSGFFGSVGTNRSQDIGPEMEIMARGALTAVGSAHLAERRYYTLSTGEARRVLMA
                     RALVNSPEALILDEPMNSLDLTGKRLVRSAIRTLAKEGRSLVLVTHDPADIVPEIDRV
                     IMIKDGGVLKDGGLQLLNEENLSILYDGPIGLRRVEDRYVAWPKDL"
     gene            complement(9380..10018)
                     /locus_tag="PKM11_06860"
     CDS             complement(9380..10018)
                     /locus_tag="PKM11_06860"
                     /inference="COORDINATES: protein motif:HMM:NF012933.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HNX48258.1"
                     /translation="MPCFEYGQVEIDYLRRRDERLGQVIDSLGMLKAEMYPDLFTALI
                     SSVIGQQISGKAAATVWNRVVERFGEITPTNLHQASLEDIQSCGTSFRKASYVKGIAE
                     ACENGGLDLEGLKALPDEEVVKALVSLKGIGPWTAEMMLIFSLGRKDVVSWGDLAIRR
                     GMISLYGLESLDRQEFDRFREKYRPYGSVASLYIWELAHRPELLATSSRKTV"
     gene            complement(10005..10472)
                     /locus_tag="PKM11_06865"
     CDS             complement(10005..10472)
                     /locus_tag="PKM11_06865"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: protein motif:HMM:NF013222.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HNX48259.1"
                     /translation="MKHVHSFMTDIGRIHVAEEDGAITNVMLPGGKAPPGTFASTPLL
                     EKAAVQISEYLQGRRQKFTVPLAPQGSDFAMKVWKEMLDIPYGKVRTYGEMAVAIGRP
                     GAARAVGQACNRNPISILIPCHRVVGAGGKLTGYAGGLDLKERLLRLEKDALL"
     gene            complement(10682..11230)
                     /locus_tag="PKM11_06870"
     CDS             complement(10682..11230)
                     /locus_tag="PKM11_06870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TATA-box-binding protein"
                     /protein_id="HNX48260.1"
                     /translation="MAKIKIENVVASTSIGDELDLWSVALALDGAEYEPEQFPGLIYR
                     IKDPKTATLLFRSGKVVCTGGRSLSHVQQAIAKVAKQIEKAGVKIKVRPEIVVQNIVA
                     SSDLNQEINLNAIAISLGLEKVEYEPEQFPGLVYRLDDPKVVVLLFGSGKLVCTGAKV
                     EKDAAEAVDKITVELKAAGLLK"
     gene            complement(11461..11976)
                     /locus_tag="PKM11_06875"
     CDS             complement(11461..11976)
                     /locus_tag="PKM11_06875"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48261.1"
                     /translation="MKFRSADSSKPEAPHLDRRKLYELTIAGGAAFWATNFAISLTPI
                     AAEYRAALSISYFPMILQSLFGGLIIGSIVSFIMLRFFDKVPAKDPILKSVMLSFIAL
                     IIVTILFQGPAGLLTPNDGLRYFLIGTSFNVVRILALGVAIGYLFKRMQFALSTGGQG
                     GVGGSSIQNGQ"
     gene            complement(11983..12741)
                     /locus_tag="PKM11_06880"
     CDS             complement(11983..12741)
                     /locus_tag="PKM11_06880"
                     /inference="COORDINATES: protein motif:HMM:NF025687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4386 domain-containing protein"
                     /protein_id="HNX48262.1"
                     /translation="MNALSFFKGNDHLSKDGDGRSSPRVRQARIAGSLYLIFIVLLPI
                     ATTIRDQLIVSGDATATAQNILANELLFRISFMIELVSALFFVLAAWALYSLLKSVNK
                     DLALLFLLLNLCGVAVQCASVLDLSTVPSLLDGTGYMTVFSADQLQAQALLHIDMYHD
                     GFILSQLFFGAWLVPLGYLVYRSGFLPRLLGILLIIDFFGVLSRFLQFFLLPEYELIS
                     YPGYAAGFIAEVSLTLWLLFKGAKENERSLTDGG"
     gene            complement(12738..13034)
                     /locus_tag="PKM11_06885"
     CDS             complement(12738..13034)
                     /locus_tag="PKM11_06885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48263.1"
                     /translation="MVLVRGMKMTRPRPVKNERMFSIELRSKGDVRNASLDGDDTVFI
                     EGSIGTLVRAHFVEDLVLEVIGSNGELRVDLAVNDLHLRSSESNGLGESQEGKR"
     gene            13115..>13833
                     /locus_tag="PKM11_06890"
     CDS             13115..>13833
                     /locus_tag="PKM11_06890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48264.1"
                     /translation="MKIDEDPVSDIHFLLTNVDRRKIIDELQTQSLKLNEVAKKLDMT
                     ATEACRQLQRLTDAGLLEKSSEGKYHSTPYSRLILESSTAMNFISKHREFFLGHDTSL
                     IPPEFRARFGELSRTALRTEAVVNINTASQVLKDAGKRIDIMTEQHLEHNAQILRQQS
                     LKGVKVRSIVQENMNEKIVEGTDLQTAWERRSVPRICAMVVLTEKVVGIALPKLDGKM
                     DYQVLEGTDPESMRWAGDLFE"
BASE COUNT         2936 a         4000 c         4036 g         2861 t
ORIGIN      
        1 gtagctgggg gaccaatgcc gtacgggagg atgtcaagcc gacttcacct tcttctttgc
       61 cttagagaga actcacatta atatcctttt ccagatttgt atccgctagt tttataagaa
      121 tcatggaagg ggattcgccc cattgacgtt tagtcgtgat ttctcgagcg atggaatttt
      181 ttttaatagt tataaatata ttatttctga aggacaggaa cagtacgatc tgaaaagcac
      241 ctggatacac gacatgaatt gagcacctga acgacgaaat gacctgagaa tggctggaat
      301 gagttcaatt agtagtaatt tgtctagaaa ttagataaat aaatagatta acatcgaaat
      361 atatacgaaa taatagacaa ttgtctatga aaaaaggcct tataatccgg acgataccag
      421 gggtattgcc tcgggcgcgc atatagccat gcgaaggaag tgaaccaccg atgatcaata
      481 gaacgggccg agagaacaag accgaccgat tgggaatgcc ggtgcaggct gagaactaca
      541 ccgccagcag accgccaggt tggcagggcc agctcggagg atgcggcatc gcctcctgta
      601 tctccctgaa gggagagaag atcagcgggg accgcatcgc ccggatgctc accatcatgg
      661 aggagagaga gaacggcctg ggggctggct acgcctgcta tggcctgttc ccggaccgcc
      721 gggaccagta ctgtctgcag ttcttctttg acgatgagga agggaagaga aacgccgaga
      781 acttcctcga cggacggctg gaaatcgtgc acgacgagaa ggtgttcacc cgggaccgtt
      841 ccaccatatc gcccccttac ccgatcgtat ggcgctactt cgccaacgta ccgggccacc
      901 gggaatggag gggcgatcgc gatctcgggg aggaggacta tatggtggag atggtccagc
      961 acgtcaatga gaagataccc aaggcattct gcgtctccag cggaaaggac atggcggtct
     1021 tcaagggtaa tggttactcg tacgagatag ctgagctgta tgacctgggg cgatattcgg
     1081 ggaccatgtg gctgtcgcat tcccgctttc ccaccaattc cccggcctgg tgggccgggg
     1141 cccatccctt gtcccttctg gactgggggg tatgccataa cggggagatc acttcatacg
     1201 gggtgaacag gaaactggtg gagatgaacg gctacaagtg cacggtgctg accgatacgg
     1261 aggtggtgac ctatctgtgg gacctgctgg tgcgccgcaa cgggctaccg gtggaggtgg
     1321 cggccttcgt catggcccct tccaccttcc aggagatatc gcagatgccg gcggcggaac
     1381 gccgcctggc cgaatggctg cggatcacgt acaaagaggc cttcctcaac gggccgttca
     1441 gcatcatcgt cgggagaagc cagcctgaga tagcgctgat cgccctggcc gataggaaga
     1501 agctgaggcc gatgatcgcg ggactatctc ctgatgatgg cgtggcgtac tgcgccagcg
     1561 aggagagcgc catacgcatc gtggagccgg acgcccgcac ctgggcgcct ggcgccggca
     1621 atccgttcat agccgtggcc ggcaagggag tggtccgcaa gggcatcgaa ccgtccttcc
     1681 agggggttag cctatgagcg agacgccagc gatgaaaaga cttgaccatc gcctcccgga
     1741 gaggttcgtg cccaccatca actatgacct gtgccgggtg tgccggcgtt gcgtcaacga
     1801 ttgctcctac caggcgctgg agttcctgga gtccagggtc gtgccctccg ggggatgcgt
     1861 ggcctgcggc cgctgcatag cggtgtgccc agccaactgc atagagatcc gcccggttcc
     1921 gccccagttc gccccgcacg gcaactggtc cgagcgtagc agaaggtcca tattggccca
     1981 ggccagctct ggcggggtcc tgctatcgtc atgcggagcg gacgacgagc atccagcgat
     2041 attcgacgac ctgctgctgg acgcggcgca ggtgaccaat ccttccatcg acccgctgcg
     2101 ggaaccggtg gagaccgtca cctacctggg acgaagacca ggtaagctgg aggtgtgcga
     2161 cgggaaggtg atgatccgag aagatgacac gcctctgata cgaatgaaca tgccgttgat
     2221 gttcgggcac atatccctgg ggtccatctc ctacaacgct cagaaggcgc tgttcatggc
     2281 cgccaaggag ctcaacatcg tggccggcag cggagagggg ggactgcacc ctgacttcta
     2341 ccagtatgcc gaccgcatat gctccgaggt cgcatccgga cgattcggga tcaagccgga
     2401 gtacctcaaa ggcgtggccg ccgtggagat caagataggg cagggcgcca agcccggtca
     2461 tggaggacat ctgccaggtg agaaggtcac caccatgatc tccgagaccc ggatgatccc
     2521 tctggggacg gacgctctgt cgccgtaccc gcatcacgac atctacagca tcgaggacct
     2581 ggcgcagctg atctccgtcc tcaaggagag caccgagtac cggcttccgg taggggtcaa
     2641 gatcgccgct gtgcacaacg tgggcgccat cgcctccggt ctggtgcggg ccggggctga
     2701 cttcctcacc gtggacggat acaagggcgg caccggcgcc gcgcctcgcg tcatcaggga
     2761 ccacgccggc ctgccggtcg aggtggccat cgccgctgtc gaccggaggc tgacccagga
     2821 agggctgcgt aatcgggtga ccgtctgcgc cgggggcggc atacgctcct cggccgacat
     2881 gataaaagcg ctggcgctgg gcgcggacgt ggtcatggtc tccacctcgg ccctggtggc
     2941 catgggctgc cgggtgtgcc agcaatgcca ccgcggtctg tgctcgtggg gcatcgccac
     3001 ccagcgggac gacctgacga acaggctcga ccctaacgtg gccgccgcgc gcatcgtccg
     3061 cctgttcaat gcctggaacg aggagctcaa ggaggtgctg ggggcaatgg gcatcgattc
     3121 ggtggaaagc ctggtcggca accgtgaccg attgcgctac cgtggcccca accccaagat
     3181 cgccgaagtg atgaacgtca agcacatcgg ggaagggtgg ggttgatgaa ggacgtctgc
     3241 aagccaaagg ggcacgccca cgagtgcgac tgcgggaagg actgcttgag cgtggtcggg
     3301 gaacgagcgg tcatcgacct gcacctttcg cccacccagc ccatgcatta caccaccctc
     3361 aattgcacca tgcgaaaggc catgcgccgc ggttgctcct ccatcgaact gaaaggggtg
     3421 atggggcagc gctacctggc gtccaccgcc tccgaccctg gcctgttcat tgccatacat
     3481 ggcaccccgg ggaacgacct aggggccttc ctcaacggac cgaccatcga ggtgttcggc
     3541 aatgcccagg acatgaccgg gaacaccatg aactcgggca agataatagt gcacggcaac
     3601 gcctgggacg taacgggact ggcggcccgg ggcggacaga tcctggttaa gggcgatacc
     3661 ggataccggg tggggatcca catgaaggag ttcggggaag cgcgaccgac cctggtcatc
     3721 ggcggaacgg ccaaggacta tcttggcgag tacatggccg gcgggaccat actggtgcta
     3781 ggattgggcg gaggcgcacc ggtcggacgt agcctggggg ccggaatgca tggcgggcgc
     3841 atcttcgtac ggggaaaggt ggcatcggaa cagctgggcc ctggcgcggc gatatccccg
     3901 ctgaaccctg aggacgagaa ggaagtgctt tccctactgg aagatttcgg gaaggcgttc
     3961 gggaccgacg ttccgtatga tgcgaaggac ttcgtcaagg tgtccccaag ttccagcagg
     4021 ccgttctccg gctactacga caagaccaac gtctagttgc ctggcaaacg gttggcggag
     4081 ctggtcacca tgcgcagctc cacgtcctcc agccccagag gtatcacctt ggcggagatg
     4141 gcctgctcca gggcgttgac gtccctggcc tgcagtcgaa ccacgatcct ccgcggaccg
     4201 gtcacctgca gcacctcctt gacctcctgc acccctctca gcttcctgag ctcttcggac
     4261 ggaacgcccg gacgcagatt ggcgaaaagt atggcgtcca ccttgagacc catgcgctca
     4321 ttgttcacca ccgcgaagta gcccagtatg atcccgtcgt cctccatgcg ctttatacgg
     4381 tcgcgcaccg tggacgggga gcgcttcagc ttggcggcta tctcgttgtg ggtcatcctg
     4441 ccgtcgttta ccagaagctg caggatgcgc cggttcatgg cgtcgaccac gggcatgtcg
     4501 ggcctttatc gcgctatgat tcttaataaa ttccgatgga acgtcgaatt gagcattgaa
     4561 aaaatgaaat aatggaagaa attgtttaaa aattagttga tttcatcgat ggacggttca
     4621 cttcacgaag agcgacggcg cctccggctt gggggagaag caggcctctc ccatctcctc
     4681 caccttcgcc ccggcctcca aggccgtatc gtagatcgcc ttctcgaaga ccttcttcag
     4741 ctcgttcggt gaggcggaca ctctggcgtt cagcacgatc ttgccttccc cggtaaagta
     4801 gcgcccccct ttcagcccgt ccacctgcat gcggtcctcc accaggctca tcttggccga
     4861 ggcggtggaa gaggtcagca tgaccttgac gtggccgatg gtctccggcg caaattccgt
     4921 ggccaccctt ctcatgaggg aggagacaaa ggcgttgatg tccacacgtc cttcagccac
     4981 caatctggcg tgggcgttga accatcccat ggatgccttc tctacggcga acatcctctg
     5041 gtccacgtcc ttgggctcct tggtgctgac ctggtccgag aggatgatgt ccactatgcg
     5101 gtccaggttc ttcctgctga aggccgagca ggggatcacc tcggcgtccg agacctcctt
     5161 tcgtatcaga tcgctggcgc ttgcgacctc cccttcgtta agacggtcca ccttggatat
     5221 cagaacgtac tccgcctccc ggacctggtg cgacggaatg agctttccgc cgcccagccc
     5281 gaagccctcc ggcttgcgca gcgtctcggc cgccctggtc ccgtccacga tgacgaagaa
     5341 cggcgccacc tggaactcgt ccgggtacat ggagcgcaga ggcgagacga cggaaccgag
     5401 aatggccgtg gaggtgccga tcggctcggc gatgatgacg tccggccgtc ccatggccac
     5461 caatgtccgg gcgttcttaa cgaactcccc gaagttggca cagaagcagc cgcccagcac
     5521 gtccttgacg tcgaacccgg cgttcttcat gtactccgtg tccacaagaa cgttgccctg
     5581 atcgttggtg atgatggcca cggaccttcc gtgcttggac ctcagctcgt tccccagggc
     5641 ggcggccaat gtggtctttc ccgctccgag gtatccaccc agcaccacga acctggtcgg
     5701 ggccttgtct ccggactgca tgcaccggtt aacgcgccgc cgggtttata cgtttcttgc
     5761 cactccaata ttacagtccc tctattcgca ccgtgcgccg taggaaagcg caggtctgac
     5821 aggggatgtc gatcacgcaa cgctgaccta ctggcatgcc tttaatggcc gccagtagcg
     5881 ccaggtccat cggccggtaa ggcgagcggc ggttgttggc ggccagcact cccctctccg
     5941 cctccgagag cgcctccgag tcaaaacggg actgggcgaa ctccatgcac ctcctcgcct
     6001 cctcctcgct gcactggtcg cagcgcgcgc ccaccttgac caccgcccca tagatgtcgg
     6061 ccaatggatc tactagaaag atcccgtggt ccttgccgat ggtgatgaag accgcgtaag
     6121 ggtatgacgc ctcgatgagc tccatgcgag taccccgcac cttcctctcc tccttcaccg
     6181 cccagaagtc ccggagatga ttattgagct ggtagaccag ctggttatag tccaatccga
     6241 gcgagtcggc caggtcctgt ttgcttatcg gcgcgtccct ggtggaccgg tagagcttgg
     6301 tcaggatccg tttcctcatg tcgtggttca cgatggaggt gtacgtctcc gggtcgatgt
     6361 aggccatctc gattcggcag tctgctgtca acatcacttg atttcattct ccaatattta
     6421 atcgttgacg aaggataggc taactgtacg cccatcgggg ataacctccc atttcaattc
     6481 atttttcatg gtgggcaaga aacaactatg ccagaggtgc ggagcaccca taagaaggga
     6541 ttacgaatac tgcaatgtgt gcggaaagag cacgtcttcc gtacctcagg cccggaggac
     6601 ctcgccggtg aacccctcca aggtgctgcc ggcccgtgaa gcgaagcgca aggaggccaa
     6661 gaacgtcgat gacgtggtac cccgtaggga gctggtcata gcgctgctgg cgatgacctg
     6721 catggccccg ttctgcactt ggctcagctc gttcggaggt ctgatcggaa ccagcgccgc
     6781 cttcaatgaa gctttctacg gccggtacgt ggtgttgctg gcggcgatgg gactgttgat
     6841 gctcttagcc ggcaaccttg tgcctgctag catcccccgc cggggcgtga tcgccggggt
     6901 gggcatcggt acggcagcgt tgaccgccct ggattacgtg gagatcatga gatacaacct
     6961 gagccccgaa tcgtccttga tcccggcgat gccgggcgta gggatgtacc tggccctggg
     7021 actggggata gcgctatccc ttgccgtgct ggtgcccaag aggaggagcg cgccttatac
     7081 ggcgacccgt ccggcgctca ggccaggttc tcggggttca gacccttgag ctcgtcgatg
     7141 acgaagcggc cgtcctttcg aaccagtacg tcatcgaagt acatctcccc gccgcccatc
     7201 tccggggtct ggatcagcac catgtcccaa tggacggtgg acttgttgcc gttgtccgac
     7261 tcctgatagg cgctgcctgg cgtgaagtgt atcgaaccgg cgatcttctc gtcgaacagg
     7321 gtgtcgagca tggcctggtt gatgtaggga ttcacaccta tggcgaactc cccgacgtat
     7381 ctggccccag ggtccgtatc gtgaatgatg ttctgggact tggtgtcgga gctggtggcc
     7441 tcgaatatct taccatcctt gaacttcagg accacgttgt cgaagacctt gccctggtag
     7501 agcgtccggg tgttgtaact tatgacgccg ttcaccgagt ccttgatggg cgcggtgtag
     7561 acctctccat caggtatgtt ccggtcgccc tcgcacttga ccgccggcat gccctttatc
     7621 gaaaaggtga ggtcggtgcc tgggctgacc aggcgcacct tgtccgtgcg ctccatcaac
     7681 gcgaccaagg gatccatggc cctggacatc ttcggatagt ccagggtgca ggtgttgaag
     7741 tagaagtcct cgaagcgctc ggtggacatc tgggcctgtt gggccatgga agatgtcggc
     7801 catctgagca ccacccacct ggtcttggga accctccagc cggtgtgcac cggcccggac
     7861 cagtacttca tgtaaaggtc gatcttgtcc gccggaacgt ccgagttctc ggtgatgttg
     7921 tacgagccgc gcatgccgat gtaggcctgg gccctcttca tcttctccag ctcgatctcg
     7981 ccgatctggg cgatggtctt ctggtcggcg ttcatgagca atttcctgaa caccttggcg
     8041 gagcggaggg ccaccatagg cactcccccg acctcgtaga tcttgtcaag aaggacctcc
     8101 accatctcgg aggggatatc gaacgcctcg atgtagaccg tctctccctt ctggaggcga
     8161 acggagtgat cgatcagcac gtcggccaac tttcgcattc tggggtcgta catacgaatc
     8221 cggctaatcc attggaaggt atatcaggat tatcaaaaat ccccgacccc gcaagatcag
     8281 gacatattac ttggacctgg agttcaaagg tccttgggcc aggcgacgta gcggtcttcc
     8341 acccggcgta gcccgatcgg tccgtcgtag aggatggaca ggttctcctc gttcagaagc
     8401 tggagccctc cgtccttgag caccccgccg tccttgatca ttatgacccg gtcgatctcc
     8461 gggacgatat cggccggatc gtgggtgacc aggaccagcg atcgcccttc cttggccaag
     8521 gtcctgatgg ccgaccggac cagtcgtttg ccggtgaggt ccagggagtt catcggctca
     8581 tccagtatca gcgcttccgg ggagttcacc agggcgcggg ccatcagcac ccggcgggcc
     8641 tcgccggtgg agagcgtgta ataccttcgc tccgccaggt gagccgatcc tacggcggtc
     8701 agggcgcccc tggccataat ttccatctcc gggccgatgt cctgcgagcg gttcgttccg
     8761 acggaaccga agaagccgga tagaacggcc tccaggcaat ccatgtcccg ggataggtcg
     8821 acctgaaggt cggcggagac cagcccgaag gcctggcgca catcgaagag gttccagagg
     8881 tccgaacctc tcagcttgac gtaggatccg ggcaccgacg tgtcgtgacg gtgctcgccc
     8941 atcatggtct tgatgagcga tgattttccg gaaccgttcg gacccagtac caccagtcgt
     9001 tcccctttgc gtatggtgag gtccacgtcc cgcaggaggg ttgccgagcc cttgctgaca
     9061 cttaccttgc gcatctcgat gatcggctcg ccgggcatgc ggaacggtat cggccgcagg
     9121 atataaaccg actaccccag ggcgccttcg ctataggtgg aacaaaatgg agaacggatt
     9181 tatcgccccc agcggggcgg acggtggcct agaaggccag aaaatgattg agagaaaaag
     9241 ggaattactt cttctttccc ttggccggag acgccgcggc agtcttcttc tcttcgttct
     9301 tcttcttttg cttaccgaga tccttcttgg acattgccat aagaactgat atggctaaat
     9361 tcatacttaa caataattat cataccgtct tcctggatga tgttgccaga agctccggcc
     9421 tatgcgccag ctcccaaatg tacagggagg cgacgcttcc gtagggccgg tacttctcgc
     9481 ggaacctgtc gaactcctgc ctgtccagag attccaggcc gtacagcgat atcatcccgc
     9541 gacggatggc caggtcaccc cagctcacca cgtccttcct tcccagggag aatatgagca
     9601 tcatctccgc ggtccagggg ccgatgccct tcagtgagac cagggccttc acgacctcct
     9661 cgtccggaag tgccttcaga ccttccaggt ccagacctcc gttctcacat gcctccgcta
     9721 tgcctttgac atagctggcc ttgcggaagg acgtgccgca ggactggata tcctcgaggg
     9781 atgcttggtg cagatttgtc ggcgtgatct cgccgaagcg ctcgaccact cggttccaga
     9841 cggtggcggc ggccttgccg gatatctgct ggccgatcac gctgcttatc aaggccgtaa
     9901 aaaggtcggg atacatctcg gccttcaaca tcccaaggga atcgatgacc tgacctagcc
     9961 tctcatctct tcggcggaga taatcgatct ctacctggcc atactcaaag cagggcatcc
    10021 ttctccaacc tcagcaatct ttccttgagg tccagacccc cggcgtagcc ggtgagcttt
    10081 cctccggcgc cgaccacccg atgacatggg ataaggatgg agatggggtt acgattgcag
    10141 gcctgaccca ccgccctggc cgctccagga cgaccgatgg ccacggccat ctcgccatag
    10201 gtgcgtacct tcccgtaggg gatatccaac atctccttcc agaccttcat ggcgaaatca
    10261 cttccctggg gagccagcgg aacggtgaac ttctggcgcc tcccctggag gtattcggat
    10321 atctggacgg cggccttttc gagaagcggg gtgctggcga acgtacctgg cggggccttc
    10381 cctccgggga gcatcacgtt ggttatcgca ccatcctctt cggccacgtg tatccgcccg
    10441 atatcggtca tgaaactatg gacatgcttc aacaggagac ctccggagct atcgctgatt
    10501 accgtttatc gttatttaag aggtgcttcg aagccgcttt ccaaggttat gatacgacca
    10561 atcactttgc tatgacggga tgagcatggt tggcccgagt ggccgagaac gaggcccgcg
    10621 agaagaagtg atcatcttcc ggagctgtcc ttcaggaaat aggtcgaaag aaaggatcgg
    10681 cctacttcag caggccggcc gccttcagct ccacggtgat cttgtcgacg gcctccgcgg
    10741 cgtccttctc gaccttggcg ccggtgcaga cgagctttcc agaaccgaac aggagcacga
    10801 ccaccttcgg atcgtccaaa cgataaacga gcccggggaa ctgctccggc tcgtactcca
    10861 ccttttccaa gccgagagag atggctatgg cgtttagatt gatctcctgg tttaggtccg
    10921 aagaggctac gatgttctgg accacgatct ctggccggac cttgatcttg accccggcct
    10981 tctcgatctg cttggcgacc ttggcgatgg cctgttgaac gtgggagagc gaacgtccgc
    11041 cggtgcagac caccttcccg ctgcggaata gcagcgtggc ggtcttgggg tccttgatgc
    11101 ggtagatcag gccgggaaac tgctccggct cgtactccgc gccatccaag gcgagggcga
    11161 cggaccaaag gtcgagctcg tccccgatgg aagtagaagc gacaacgttc tcgatcttga
    11221 tcttggccat gatgccccct ttcctcacgt tatttaaata tccagttaaa agtttttcga
    11281 tatggcctta tattagatgg accgcgaccg tcatatagaa taggaccggc ccggaccatt
    11341 ttggcattgc gcggggcgaa attcagccct attgaaaagg taggtttggc tgagatcgca
    11401 gatttgaaaa tgcaaatgat taaaattttt tacgatgcac aaccaagcca gttttctcat
    11461 ctattgacca ttttgaatgg atgagccccc aacccctcct tggcctccag ttgataaggc
    11521 gaattgcatt cttttaaaga gatatccaat ggccacccct agggcgagaa tccttactac
    11581 attgaacgag gtgccaatta ggaagtagcg caacccatca tttggggtga gaagacccgc
    11641 cggaccttgg aacagtattg tgactatgat gagggcgatg aaactgagca tcacggattt
    11701 taggatcggg tccttggctg ggaccttgtc aaagaatcga agcatgatga aactgacgat
    11761 agatccgatg ataagaccgc cgaacaaaga ttgaaggatc atcgggaaat acgagatgga
    11821 gagagcggcc ctatactcgg cggcgatggg cgtcaatgag attgcgaagt tggtcgccca
    11881 gaaggcagct cctcccgcga tggtcagttc atacagcttt cttctatcca gatgcggcgc
    11941 ctccggtttg cttgaatccg cagatctgaa tttcatagtg gatcagcccc catcggtcag
    12001 agaccgttcg ttttcctttg ctcccttgaa cagaagccac agcgtcaggg atacctcggc
    12061 gatgaagcct gccgcgtaac cagggtatga tatgagctcg tactccggga gcaggaagaa
    12121 ctgcaggaat cgtgacagca caccgaagaa gtcgattatc agtaggatgc ctaacagccg
    12181 gggaaggaag cctgaccggt agaccagata cccgaggggt accaaccagg cgccaaagaa
    12241 gagctgggag aggatgaaac cgtcgtggta catgtcgata tgcaacaggg cctgagcctg
    12301 aagctgatcc gctgagaaca cggtcatata accagtaccg tccaacagcg atgggaccgt
    12361 agacagatcg agcacgcttg cgcattggac cgcgaccccg cacagattca ataacaggaa
    12421 aagaagggcg agatccttat taacggactt cagcagcgaa tagagagccc aggcggccag
    12481 aacgaagaac agggccgaaa ccagctcgat catgaaactg attcggaaca gtagctcgtt
    12541 cgccaaaatg ttctgggccg tggcagtggc atccccggac acgataagct ggtcgcgaat
    12601 ggtggtggcg ataggcaata acacgatgaa gatcagatag agcgaccctg cgatccttgc
    12661 ttgcctgacc ctcgggctgg atcgcccatc tccatccttc gaaaggtgat cattcccctt
    12721 aaagaaggaa agggcgttca tcgctttccc tcctggctct ccccgagccc attagattca
    12781 cttgaccgca gatgcaggtc gttcaccgca agatctaccc tcagttcgcc attgcttcct
    12841 atgacttcca gaaccaggtc ttccacgaaa tgggctctta ccaatgttcc aatggaacct
    12901 tcgatgaaga ccgtatcgtc cccatccagg gatgcgttcc tcacatcccc tttcgatctg
    12961 agctcgattg agaacatccg ttcatttttt acaggtcttg gtcgggtcat tttcatacca
    13021 cggaccaaaa ccattgcgaa acgatgctga taattattat ttgactcgta tgtgctgttg
    13081 taaacatcgg cgtgtaggtg ttatcgtgga aaaaatgaag atcgatgagg accccgtctc
    13141 cgacatccat tttctattga cgaacgtaga ccggcgtaag ataatcgatg agcttcaaac
    13201 gcagagcctc aagctgaacg aggtggcgaa gaagctggac atgaccgcca ccgaggcctg
    13261 cagacagctg caacggctga ccgatgctgg tcttttagaa aaatcatccg agggcaagta
    13321 tcattccacc ccttattcca ggctcatact ggaatcctcc accgccatga acttcatttc
    13381 caagcaccga gaattcttct tgggacacga tacctcgctc attcctcctg agttccgcgc
    13441 caggttcgga gagctatcga ggaccgccct tcgcactgag gcggtcgtta acatcaacac
    13501 cgcttctcag gtcctaaagg acgccggtaa gcggatagat attatgaccg agcagcacct
    13561 agagcacaat gcccagatac tccgacaaca gtcgttgaag ggagtgaagg tcaggtccat
    13621 cgtacaggag aacatgaatg aaaagatagt tgaagggacc gatctgcaga ccgcgtggga
    13681 gaggagaagc gttcccagaa tttgcgcgat ggtcgtccta acggaaaagg tcgtagggat
    13741 cgcgctaccg aagttggacg gaaagatgga ttatcaggtc ttggaaggaa ccgacccgga
    13801 atcgatgaga tgggcagggg acctcttcga aca
//
LOCUS       DAOPZI010000035        13315 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_5119_length_13315_cov_8.474736, whole genome shotgun sequence.
ACCESSION   DAOPZI010000035 DAOPZI010000000
VERSION     DAOPZI010000035.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 13315)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 13315)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13315
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5119_length_13315_cov_8.474736"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1821
                     /locus_tag="PKM11_06895"
     CDS             <1..1821
                     /locus_tag="PKM11_06895"
                     /inference="COORDINATES: protein motif:HMM:NF012905.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HNX48265.1"
                     /translation="LIRKLQAVETMGSVTTICSDKTGTLTTNQMTARRIFVGGKDISI
                     SGAGYVPEGEFASAGEKLGLAEEDLVLLLRASLLCNDSRLRLHEVDGGSKWEIAGDPT
                     EGALVVAARKAGLLQEEENRNFPRIEEVPFDAKRRFMATFHKDKGKVLIQVKGAPETI
                     LGMCDQVQEGEKVRSMTAEDRKVIMDRSGSMAEDALRVLGVASRTIEENELKPVKQSM
                     MDSGEKLTFLGLIGMIDPPRPEVKRAVSLCHQAGIKVIMCTGDHKKTAEAIARELGIL
                     KGGQRVVEGEELDGMDSATLDAMVLDVAVFARVSPKNKHSIVESLRRRGHIVAMTGDG
                     VNDAPALKASNVGISMGITGTDVTKETADMVLTDDNFATIVNAVEEGRVVFENIRKVV
                     KYLITTNTGEIITILGFLLLLAGTNGIDFLILTPIMILYINLVTDGLLDKTLAMEPGE
                     PHIMDEPPRSPDARIITFKMVQNIFILGVTMAVGTLFLFDRAFSSLSDPQEAKAKAMT
                     VAFVTMAAFQIWNSMNCRSRTRSVFRMKLTGNRFLLMGMASSATLLYLATELSFFQVG
                     LGTVSLSVWDWASVFLVSSTILVVEEVRKFLQARMGGCKA"
     gene            2165..4264
                     /locus_tag="PKM11_06900"
     CDS             2165..4264
                     /locus_tag="PKM11_06900"
                     /inference="COORDINATES: protein motif:HMM:TIGR02717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HNX48266.1"
                     /translation="MRELFEPASVAVIGASAESNKVGNIILGNIIESGFQGPLYPINP
                     RYPEIMGLKCYPRVIDVPGPVEMAVVVVPAKFVLQVMEECGQKGVRAAVVISAGFKEV
                     GLEGAKLERQLGEIAHRYGMRVVGPNCLGLVNTHHHLNATFAQEAPREGNIAISSQSG
                     AICVVVLDWAANINIGFSKFISVGNKLDVDEGHLLEYLRDDQHTKVIGMYIEGTDRGR
                     EFLKQAELTTRVKPVIALKAGRTSSGAKAASSHTGAMSGSDKVYDAAMRQAGVVRVKN
                     IEELFDLLQAFSTMPLPEGEGVAIVTNAGGLGVMAADACSDNGLTLATFEAATIERLK
                     QGLPPAASLYNPIDVVGDADAARYDHAIRTVMDDPNVACVVALLAPTDLVDISSVART
                     LTAFAGSSPKPIVTSFVGGKEMMAPIDMLKAAGVPNYPSPERGIRALAAMVEHRRSLD
                     RKESHAVRPMDADHEAVREVISSVRSEGRLQLSEGEGKRILKAYGIATPQEGIAHDLA
                     SAQKLARDIGYPVVMKVESPDIAHKTDVGGVVLNIDDDQELERSYQVMLSKVREKLPN
                     AKVTGVSIQKMVKGREVIVGMVRDDQFGPVITFGLGGIFVEILRDVTQGIAPLDRDDV
                     ERMVRSIRAYPMLAGARGKRPGDIPALVEIILKISQMAMEVPDLEELEMNPVMVGDEG
                     TGVIAVDALVTIKGEQQ"
     gene            4261..5259
                     /locus_tag="PKM11_06905"
     CDS             4261..5259
                     /locus_tag="PKM11_06905"
                     /inference="COORDINATES: protein motif:HMM:NF024891.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HNX48267.1"
                     /translation="MRSLYLGSVVEKSGKSMVTLGLAKNFQGKVGFFKPFKERLMREG
                     DRVIDQDAYLMRHMLKSDKPEEVLCPFAYDVFRAATMDEVKAAYEKAACDCEMMLIEG
                     TREVTTGYMNDVSGLAIAEATGSDLILISTSEAAALDKIAMLYKLSKNYKINVKGVIL
                     NKTDDLSVANFLESKGIKVLGCVPHIPEMTYFTVKEVAEALSANVIVGEGHMDKVVEG
                     VFIGAMTMETALKYMRRHRRKAIITGGDRSDIQLAALSTDTSCLILTGGMYPANQVVS
                     KAYEKGIPILVTRYDTLATSEMVEHLIARIEPQDAEKVRLVEKAVADNVDLEAVFR"
     gene            5303..5584
                     /locus_tag="PKM11_06910"
     CDS             5303..5584
                     /locus_tag="PKM11_06910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HNX48268.1"
                     /translation="MVKEVRAAHILVAKEDKAKELLQMIKNGSSFGDLAKQFSMCPSG
                     KKGGDLGWFGKNMMVKEFEDAAFNHAKGEIVGPVKTQFGWHLIQVVDQK"
     gene            complement(5588..8008)
                     /locus_tag="PKM11_06915"
     CDS             complement(5588..8008)
                     /locus_tag="PKM11_06915"
                     /inference="COORDINATES: protein motif:HMM:NF014516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HNX48269.1"
                     /translation="MRLRYMELRNYRKFRDARIEFPDGVVAIVGSNGSGKTTILEAVT
                     WALFGNVSSVMRDNKEGVVSFGASPGEECAVVLEFDLGEDSYRLARSMKGKNLVMDAS
                     LEVNGKLLAKGDTDVTKAIVAKLGMDHQAFFVSVFTKQKDLNALANIGPADRKKLVLR
                     MLRVDSLEKVITAIGADANNAKREADGVSASLRDADGNDRIESLKEQERAAADSLKKL
                     IDGSSKLLADRQAAIEKSQMTRGQWEAEEERYRQDVSLERKQTGARAGLQAMHESLGK
                     LEKEIADLRALRESLPGLESKDKEYQEARTAAERHTTLREQFLRRQRQEEELNAKKGE
                     LETLRAEEEQAVKEMSILPDIETSLTTVDANLSETRELISSISAQARVAESEAARLRV
                     ELERSKRKAEEIVKLGEDSNCPTCQRRMGAQYTDLLRRYREEQKALEEGAALQDDIRK
                     GQLEQRTRTEQRRDALEARRSKLLSQSRLKASLDERARKAQQSISLMKEKLDALQKGL
                     DSLGPVAYDAAAHDAAKRKASDLEPSHLALNRAMTKMERLPLAMEEKDRMAIAVASEE
                     EALRAASQERRALGFEMKTLLLKKKEHEEARQSEERLAQDVIRAEGEQRRLASEIESL
                     RKQTAELERSRLKYVSLMKEQEILNRLSQVMKGFKENVISRIVPTLSDTSSDLLSQLT
                     EGKYSGMRLDENYQMWLYDQGEEFRLERFSGGEVDLANLCLRLAISRMIMERSGNQMN
                     FLVLDEIFGSQDQSRKRSILETLGQLQKQFRQILLITHIDDVKDNVSAVLRVQEKEDG
                     SSTAVLEG"
     gene            complement(8005..9117)
                     /locus_tag="PKM11_06920"
     CDS             complement(8005..9117)
                     /locus_tag="PKM11_06920"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HNX48270.1"
                     /translation="MRIAHIADTHVGFSAYRRSDPETGMNQREVDVYQAFERLVDSLI
                     TKRPDVVLHSGDLFDSVRPSNRALSVVLEQLLRLSDASIPVVLIAGNHSTPRLKETGS
                     VFRLFEHIKGVTPFYTPGMHRLDLGDLTVTAFPHQDKESMVNALQSWKRGHSRYEVGM
                     LHAGIQGLTRYSMGEANELNLPSSLLNLEADYIALGHFHDREQITENAWYSGSLERLS
                     FAEAGQEKGYNLVDLERDRKEFVRLPTRPMYSLGPFKAKGKEANVLQDELMAALGSVK
                     VEGSIVRLVVKDVPAALYRSLDLNALRAMAEKAVHLDLNLEIVQGTDAVQWRSTTFGS
                     LGQEFEAYLSQVPVEGVDKDELRRRGLDYLGKEAGE"
     gene            complement(9177..10931)
                     /locus_tag="PKM11_06925"
     CDS             complement(9177..10931)
                     /locus_tag="PKM11_06925"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX48271.1"
                     /translation="MVSETTFLLEMAIIMVTAGVISVIFSKLRLPVVIGYLAAGMILG
                     PNLFEPSFVTDLDTINALANAGIVLLMFTLGLEFNLRRLKKVGLFAALAGSVEIVLMI
                     TLGYGLGIALGWSPIQSIFLGAVMSISSTAVIIKVLSDAGMMSKEFAEAIVGILIIED
                     IAAVIILTLASPLAAGDGVTITTIVLQVAYIGAFMIILLVLGLAVLPKLMDRMYPVSS
                     PETLLIVSLGMCFGMAIVAYFFGLSVAIGAFLVGIIISQSVAQEKIVERITPIKEMFM
                     ALFFISIGLLIDPWLIMNNIFVAVAIAAVFIIGKMFSVTIGTFLSNKNARTSAMTGLG
                     MVAMGEFSFVIAKTAFDLGAVDQLFYSSVIGAALLTMLYLPASFRRAPQIVTVLGDAL
                     PASVRESLRRVDHLRTDMGVWMNAHADRRREVQRQIFWIFIDIVIIFILQVLAVTFYD
                     IVGLFGVDADGLGAITYMVATAIFIGLMLPPLINILSRVRLIGLMLIRGVMEAGHFET
                     GAEGRLLRVFVNLIISIIGVVLFFLFIPIAPQVAGFPVLLVFGIAVGLVIAYLLWDAN
                     KSAYDRMCHILADRLHEE"
     gene            complement(10941..>11219)
                     /locus_tag="PKM11_06930"
     CDS             complement(10941..>11219)
                     /locus_tag="PKM11_06930"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48272.1"
                     /translation="EEIISQFNTLFILGLADKRDRDILRNSAKQDISMLDNEIQMLMP
                     GEALIASPFTPFAIPCKVHLYEEYVEESNAKIGERKNTVTKDVGQTFF"
     assembly_gap    11220..11319
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<11320..12285)
                     /locus_tag="PKM11_06935"
     CDS             complement(<11320..12285)
                     /locus_tag="PKM11_06935"
                     /inference="COORDINATES: protein motif:HMM:NF014044.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX48273.1"
                     /translation="MTDIGRIFGNKVMELRFRTSEAEDLQVGEMLVVEEGGVKFLVRT
                     MDVLFGADSDDDDYLEWQAGVALKDGFDYERIKGDLYKVGVCTPLGCLKDSRYRKAKS
                     IPRHFSRVRRADQDDYDFLKPLMGDVEVGRLRSGDRVLDFRVGIDSRGFPHHVGIFAT
                     TGMGKSNLMKSLALSCMESRRCGFLILDPHGEYFDGGERGKKGLSHSKLAPEALDVYS
                     SRRLDGPHSSIHISSSEIEIPDLANLYEFSGPQLECLQASQWKYGEKWLDELRDKSVA
                     TIVTDLNGRFHEGSVNVIKRRLDSIFQFDLVTTDHNLSMTRAVISA"
     gene            12372..13280
                     /locus_tag="PKM11_06940"
     CDS             12372..13280
                     /locus_tag="PKM11_06940"
                     /inference="COORDINATES: protein motif:HMM:NF012320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48274.1"
                     /translation="MRPDIIELPAQSTLPRPEVLVVGVGGAGRHMAAQMPGNKVAVSL
                     EGDAGIPGHRQVLLRKGEVTVARTSSPTALHVSDLPWKNRLLEAVGRPEVLFLFSGLG
                     GETGSYIAPLITELAHYTTMTFASVCLPFSVEGSNRRAMAKEGLVRLKAASHMVAVYA
                     NDPLIKLAPNLPLSKAFGVMDHIMLSLPTDLCQCLTAEAMPLLKENMGRKELRAGIGY
                     GLGLERERLAVEDALTSPWFPSAEFQPDTALMLVTLGQEDRISTDDCVKEMSERLKVR
                     KLLVASHVDPSLGRRVKVSLLLGYSF"
BASE COUNT         2651 a         3942 c         4029 g         2593 t
ORIGIN      
        1 ctgatacgaa agctgcaggc ggtggagacg atgggctcgg tcaccaccat atgttcggac
       61 aagaccggga ccctgaccac caaccagatg accgctcgcc ggatctttgt gggtgggaag
      121 gacataagca tatccggcgc cgggtacgtc ccggagggcg agttcgcctc tgcaggcgaa
      181 aagctgggtc tcgccgaaga ggacctggtc ctcttgctga gggccagcct tctctgcaac
      241 gattctcgtc tgcgcctgca cgaggtggac ggcggttcca agtgggagat cgccggagac
      301 cccacagagg gcgccctggt cgtcgccgcg cgcaaggccg ggctgttgca ggaggaggag
      361 aacaggaact ttccacggat cgaggaggtg cccttcgacg ccaagcgccg gttcatggcc
      421 accttccaca aggacaaggg aaaggtgctg atacaggtca agggcgcccc cgagacgatc
      481 ctagggatgt gtgatcaagt ccaagagggg gaaaaggtcc ggagcatgac cgccgaggac
      541 cgcaaggtca taatggaccg cagcggttcg atggccgagg acgccctgag agtgctcgga
      601 gtggcctccc ggaccatcga ggagaacgag ctaaagcccg tcaagcagag catgatggat
      661 tccggagaga agctgacctt cctggggctg atagggatga tcgaccctcc tcggccagag
      721 gtgaagaggg cggtgagcct ttgccaccag gccggcatca aggtcatcat gtgcaccggc
      781 gaccacaaga agaccgccga ggccatcgcc cgggagctgg gcatactgaa aggcggccag
      841 agggtggttg aaggggaaga gctggatggc atggactcgg cgacacttga cgccatggta
      901 ctcgatgtgg cggtgttcgc ccgggtgtcg cccaagaaca agcactccat cgtggaatca
      961 ctgcggcgta gaggtcatat cgtagccatg accggggatg gggtgaacga cgccccggcg
     1021 cttaaagcgt ccaacgtcgg gatatccatg ggcatcactg gcacggacgt caccaaggag
     1081 accgcggaca tggtgctgac cgacgacaac ttcgctacca tagtcaacgc ggtggaggag
     1141 ggaagggtgg tcttcgagaa catcaggaag gtggtgaagt acctgatcac caccaacacc
     1201 ggggagataa tcaccatact gggattcctc ctgctgctgg ctgggaccaa tggcattgac
     1261 ttcctgatcc tgacgccgat catgatcctg tacatcaacc tggtgacgga cggactgctg
     1321 gacaagactc tggccatgga gcctggcgaa ccgcacatca tggacgagcc gccccgctca
     1381 ccggatgcca ggatcatcac cttcaagatg gtccagaaca tcttcatcct gggcgtgacc
     1441 atggcggtgg gtaccctgtt cctgttcgac agggccttct ccagcctgtc cgacccgcag
     1501 gaggctaagg ccaaggccat gaccgtggcc ttcgtgacca tggccgcgtt ccagatatgg
     1561 aattcaatga actgccggtc ccggacccgc tccgtcttca ggatgaagct gaccggcaat
     1621 cgcttcctgc tgatgggaat ggcgtcctcg gccaccctgc tgtacctggc caccgaactg
     1681 tccttcttcc aggtggggct gggcacggta tcgctttccg tctgggactg ggcctcggta
     1741 ttccttgtct ccagcaccat actggtggtg gaggaggtcc ggaagttctt acaggccaga
     1801 atgggaggct gcaaggccta ggccgcaaac gtctttaaaa acctcttttt ccttttttca
     1861 aatcgacagt gtgtgccccc cgccctaaca gatcggttca tggccgcggc ggaccgcgct
     1921 ccccgcactg acccgggcaa ggggttcgtt gtcgtgcccc ggggttgtcc tccagtcatg
     1981 acgcgatgtc gcatcgcagt tcctgcaggg acctatcggc gcactgtgca ccgccagact
     2041 attgtaggga tcatgatcac cctcattttt actggcggcg tacttcatca ggccgaccgg
     2101 gcatatcaat gttgcgggtt cgaccgcaaa ggatatgacc gccgaccagc cattccgtcc
     2161 acgaatgcga gagcttttcg agccggcaag cgtggcggtg atcggcgctt ctgccgagag
     2221 caacaaggta ggcaatatca tcctgggcaa catcattgaa tccggtttcc aggggccgct
     2281 ttaccctatt aacccccgtt atccggagat aatggggttg aagtgctatc caagggtgat
     2341 cgacgttccc gggccggtgg agatggccgt tgtcgtcgtc ccggccaagt tcgtcctgca
     2401 ggtcatggag gaatgcggcc agaagggggt cagggcggcg gtcgtcataa gcgccggctt
     2461 caaggaggtc ggactggaag gggccaagct cgaaaggcag ctgggcgaga tcgcgcatcg
     2521 ttatggcatg cgggtggtcg gaccgaactg cctggggctg gtcaacaccc atcaccacct
     2581 gaacgccacc ttcgctcagg aagcgccgcg ggagggcaac atagccatct cctctcaatc
     2641 aggtgccatc tgcgtggtgg tcctggactg ggcggcgaac atcaatatcg gtttttccaa
     2701 gttcataagc gtcggcaaca agctggacgt ggacgagggg catctgctgg aatatctgag
     2761 ggatgaccag cacaccaagg tcatcggaat gtacatcgag ggaacggacc ggggcaggga
     2821 gttcctcaaa caggccgagc tgaccaccag ggtgaagcct gtaatcgctc ttaaggccgg
     2881 acgcaccagt agcggggcca aggcagcatc atcgcacact ggcgccatgt ccgggagcga
     2941 caaggtgtat gacgcggcga tgcgccaggc cggcgtcgtg cgagttaaga acatcgagga
     3001 gctgttcgat cttctgcaag cgttctccac catgcctctg ccggaaggtg agggcgtggc
     3061 catagtcacc aacgccggcg gtcttggcgt gatggccgcg gacgcctgct ccgataacgg
     3121 actgacctta gccacgttcg aggcggcgac catcgagagg ttgaagcagg gactgcctcc
     3181 cgcggccagc ctttacaatc ccatcgacgt ggtcggtgat gcggacgccg cacgttacga
     3241 tcacgccatt cgcacggtga tggacgatcc gaacgtggcc tgcgtggtcg ccctgttggc
     3301 gccgaccgac ctggtggaca tctcgtcggt ggcaaggacg cttacggcgt ttgccggttc
     3361 atctccgaaa ccgatcgtga cctccttcgt cggcggaaag gagatgatgg ccccgatcga
     3421 catgctcaag gccgccgggg ttccgaacta tccttccccg gagcggggca tacgggccct
     3481 ggcggcgatg gtggagcacc gccgcagcct ggaccgcaag gagtcacacg ccgtgaggcc
     3541 gatggatgcc gaccatgagg cggtgcgcga ggtcatatcg tctgtacgtt ccgaagggcg
     3601 cctgcagctc agtgagggcg agggcaagcg catcctgaag gcgtatggca tagccactcc
     3661 gcaggagggc atcgcccacg acctggcctc ggcgcagaaa ctagctaggg atatcggcta
     3721 tccggtggtc atgaaggtcg aatcgcccga tatcgcccac aagaccgacg tcggcggggt
     3781 ggtgctgaac attgacgacg atcaggagct ggagcgttcc tatcaggtca tgctgagcaa
     3841 ggtgcgggag aagctgccta acgccaaggt caccggcgtt tccattcaga agatggtcaa
     3901 aggtcgcgag gtgatagtcg gcatggtgcg ggacgaccag ttcggcccgg tcatcacctt
     3961 cggactgggt gggatattcg tggagatttt acgcgacgtc acgcagggga tcgcacccct
     4021 ggaccgggac gacgtggagc gcatggtccg ttccatacgg gcctatccga tgctggccgg
     4081 agcccgcggc aagcgtccgg gggacatacc ggcactggtg gagatcatac taaagatctc
     4141 ccagatggcc atggaggtcc ctgatctgga ggaactggaa atgaacccgg taatggtggg
     4201 ggacgaggga acgggtgtta tagcggtcga cgcgttggtt actatcaagg gggagcagca
     4261 atgaggtctc tgtatctagg ttcggtagtg gagaagtccg gcaagtccat ggtcactctc
     4321 ggacttgcta agaacttcca gggtaaggtg ggcttcttca agcccttcaa ggaacgtctc
     4381 atgcgggagg gggaccgggt gatcgaccag gatgcctacc tcatgcggca catgctcaaa
     4441 tcggataaac cggaggaggt gctgtgcccc ttcgcctacg acgtgttccg agcggcgacc
     4501 atggacgagg tgaaagcggc ctacgaaaaa gcggcctgcg attgtgagat gatgctgatc
     4561 gaggggacca gggaggtgac cacaggttat atgaacgacg tgtccggact ggcgatagcc
     4621 gaggccacgg gttcggacct gatactcatc tccacgtcgg aggcggccgc cctggacaag
     4681 atcgccatgc tctacaagct cagcaagaac tacaagatca acgtcaaagg ggtcatcctg
     4741 aacaagacgg acgatctctc ggtggcgaac ttcctggaga gcaaggggat caaggttctg
     4801 ggctgcgttc cacacattcc ggagatgacc tacttcacgg tcaaggaggt ggcggaagcg
     4861 ctatctgcta acgtcatcgt cggcgaaggt catatggata aggtggtgga aggggtgttc
     4921 atcggggcca tgaccatgga gaccgccctc aagtacatgc gccgtcaccg ccgcaaggcc
     4981 ataataaccg ggggcgaccg ctcggacatc cagcttgccg cattgtccac ggatacgtca
     5041 tgcctcatac tcaccggcgg aatgtatccg gcgaaccagg tggtctcgaa ggcatacgag
     5101 aaggggattc caatactggt caccaggtat gatactctgg ccacctcgga gatggtggaa
     5161 catctcatcg cccgcatcga gccccaggac gcggagaagg tgcgtctggt ggagaaggcc
     5221 gtggccgata acgtggacct cgaggcggtc ttccgctagt ggggacagat aaattaatac
     5281 cgttcccgac gatgcgcgtg acatggtcaa agaagtaagg gcagctcaca tcctggtggc
     5341 caaagaggac aaggccaagg aactcctgca gatgatcaag aacggcagca gcttcggcga
     5401 tctggccaag cagttctcca tgtgcccctc cggaaagaag ggcggggacc tcggctggtt
     5461 cggcaagaac atgatggtga aggagttcga ggacgccgcc ttcaaccacg ccaagggcga
     5521 gatcgtcggt ccggtcaaga cccagttcgg ctggcacctc atccaggtcg tcgaccagaa
     5581 gtaaaaacta accttccagc accgccgtgc tggatccatc ctctttttct tgcaccctta
     5641 gaacggcgct cacattgtcc ttgacatcgt ctatgtgggt tatgagcagt atctgccgga
     5701 actgcttctg caactgacca agcgtctcca ggatgctgcg cttgcgtgat tggtcctgcg
     5761 agccgaatat ctcgtccagc accaggaagt tcatctggtt gccggagcgt tccattatca
     5821 tgcgggagat cgccagacga aggcagagat tggccaggtc gacctctccg cccgagaaac
     5881 gctccaggcg gaactcctcc ccctggtcgt atagccacat ctgatagttc tcgtccaggc
     5941 gcatcccgct gtacttccct tcggtgagct gggacaggag atcggacgag gtgtcggaga
     6001 gggtgggaac gatgcgggag atgacgttct ccttgaaacc cttcatcacc tggctcaggc
     6061 gatttaggat ctcctgttcc ttcatcaagg agacatattt caggcgcgac ctttccagtt
     6121 ccgcggtctg ctttcgcaag gactcgatct cggaagcgag ccggcgttgc tcaccctccg
     6181 ccctgatgac atcctgggcc agacgctcct cgctctgcct ggcctcttcg tgctcctttt
     6241 tcttgagcag cagggtcttc atctcgaagc ccagcgccct gcgctcctgg gaggcggccc
     6301 ggagcgcctc ctcctcactg gccacggcga tggccatcct gtccttctcc tccatggcca
     6361 ggggaagccg ctccatcttg gtcatggccc gattgagggc gagatgtgaa ggctccagat
     6421 cggacgcctt gcgcttggcg gcatcatgcg ccgcggcatc gtacgccacc ggtcccaggg
     6481 aatccagccc cttctgcagg gcgtccagct tctccttcat tagagaaatg gattgctgcg
     6541 ccttgcgcgc cctttcatca agggaggcct tcaagcggga ttgcgagagg agcttggacc
     6601 ttcgcgcctc caaagcatca cgtcgctgct cggtgcgggt gcgctgctcc aactgccctt
     6661 tccggatatc gtcctgcagg gccgctcctt cctccaacgc cttctgctct tcccggtacc
     6721 ggcgcagcag gtcggtgtat tgcgccccca tgcgcctctg gcacgtcgga cagttgctgt
     6781 cctcgccgag cttgacgatc tcctcggcct tccgcttcga tctttccagc tcgacacgca
     6841 gccgggccgc ttccgactcg gccacccggg cctgggcgga tatggatgat atgagctccc
     6901 tggtctcgct caggttggcg tcgaccgtgg tcaggctggt ctcaatgtcc ggcaggatgg
     6961 acatctcctt gaccgcctgc tcctcctccg cccgcagggt ctcaagctcg cccttcttgg
     7021 cgttcagctc ctcctcctgc ctctggcgcc tgaggaactg ttcacggagc gtggtatgcc
     7081 tttccgcagc ggtcctggcc tcctggtatt ccttatcctt ggattccagt ccgggaaggg
     7141 attcgcgaag ggccctaagg tccgcgatct ccttctccag cttaccaagg gactcatgca
     7201 tggcctgcag tccggcccgg gcgccggtct gctttctttc caaggacacg tcctggcggt
     7261 agcgctcctc ctccgcctcc cactgccccc tggtcatctg gctcttttcg atcgccgcct
     7321 gccgatcggc caggagcttc gagcttccgt cgatcagctt tttcaacgaa tcggcggcgg
     7381 cgcgctcctg ttctttcagg gattcgatcc tatcgttccc gtcggcgtca cgcagcgagg
     7441 ccgatactcc atcggcctct ctcttcgcgt tattggcgtc agcaccgatg gcggtgatga
     7501 ccttttccag ggaatccacg cggagcatcc gcagcaccag cttcttgcgg tccgccggac
     7561 ctatgttggc cagagcgttc aggtccttct gcttggtgaa cacggacacg aagaaggcct
     7621 ggtggtccat ccccagcttg gcgacgatgg ccttggtgac gtccgtatcc cccttcgcca
     7681 acagcttccc gttgacctcc aaggaggcgt ccatcaccag gttcttacct ttcatgctgc
     7741 gggccaaacg ataggagtcc tcgccgaggt cgaactccag caccaccgcg cattcctccc
     7801 ccggggacgc gccgaagctg accacgccct ccttgttgtc cctcatgacc gacgagacgt
     7861 tgccaaagag cgcccaggtc accgcctcca ggatggtggt cttgccggag ccgttgcttc
     7921 ctacgatggc caccacgccg tccgggaact cgatgcgggc gtcgcggaac ttgcgatagt
     7981 tgcgcagctc catgtagcgc agcctcattc tccggcctcc ttgcccagat aatcgaggcc
     8041 gcggcggcgc agctcatcct tgtccacgcc ctccactggc acttgcgaca ggtatgcttc
     8101 gaattcctgg cccaaggaac cgaaggtcgt cgaccgccac tgcacggcgt ccgttccctg
     8161 cacgatctcc aggttcaggt ccaggtgaac ggccttctcg gccatggccc gcagggcgtt
     8221 gaggtccagg ctgcggtaca gcgccgcagg gacgtccttc accactaggc gcacaatgct
     8281 cccctcgacc tttaccgagc caagggcggc catcagttcg tcctgcagca cgttggcctc
     8341 ctttcccttg gccttgaacg gacctaggga atacatcggc cgggtcggca atcgaacgaa
     8401 ctccttccta tcgcgctcca ggtcgacgag gttgtatccc ttctcctggc cagcctcggc
     8461 gaaggacagg cgctccaacg atccgctgta ccaggcgttc tcagtgatct gctcccgatc
     8521 gtggaaatgc ccgagggcga tgtaatccgc ctccaggttc aggagggagg agggcaggtt
     8581 gagttcgttc gcctcgccca tgctgtagcg ggtaagtccc tggataccgg cgtgcagcat
     8641 tcccacctcg taccggctat gaccgcgctt ccagctctgg agcgcgttaa ccatggattc
     8701 cttgtcctga tgggggaagg cggtgaccgt cagatcgcct aggtctaggc gatgcattcc
     8761 cggcgtatag aacggcgtga cgcccttgat atgctcgaac aggcggaaca cgctgcccgt
     8821 ctccttgaga cggggtgtgg aatggttgcc ggcgatgagc accactggga tgctcgcatc
     8881 ggataaccgc agaagctgct ccaggaccac cgacagcgct ctgttggaag gccttacgga
     8941 atcgaacagg tcgccggagt gcaacaccac gtccggacgc ttggttatga gggaatcgac
     9001 caggcgctca aaggcctggt atacgtccac ctcgcgctgg ttcatccctg tttcagggtc
     9061 cgagcggcga taggcagaaa agccgacgtg agtgtcagcg atgtgagcga tcctcatccg
     9121 gcagggatta gatgactcgg tttaaataag ctttagattg ggggcattga aaatgctcat
     9181 tcctcatgca gccggtccgc taggatgtgg cacatgcggt cgtaggcgct cttgttggcg
     9241 tcccaaagaa gataggcgat gaccagtccc acggcgatgc caaacaccag cagcaccggg
     9301 aaacccgcca cctgaggggc gatgggaatg aacaggaaga aaagaacaac tccgattatg
     9361 gatattatca ggttgacgaa aacccttaag agccttccct ccgcgccagt ctcaaagtgc
     9421 ccagcctcca tcactccgcg gatgagcatc agtccgatca acctgacccg gctcaggatg
     9481 ttgatgagcg gtggaagcat caatccgatg aagatggccg tggccaccat gtaggtgatc
     9541 gccccgaggc cgtccgcgtc cactccgaaa aggccgacta tgtcgtagaa ggtgaccgcc
     9601 agcacctgga gaataaagat gatgacgatg tcgatgaata tccagaatat ctgcctctga
     9661 acctcccgcc ggcggtcggc gtgagcgttc atccagactc ccatgtcggt tcgtaggtgg
     9721 tccacccggc gcaacgattc cctaaccgaa gcgggcaggg catctcccag gacggtgacg
     9781 atctgcggcg ccctgcggaa cgaggccggc aggtagagca tggtcagaag tgcggctccg
     9841 atcaccgagg agtagaacaa ctggtccacc gcccccaggt cgaaggcggt cttggcgatg
     9901 acgaacgaga actcgcccat ggccaccatg cccagtccgg tcatggccga ggtgcgcgcg
     9961 ttcttgttgc tcaggaaggt gccgatggtc acgctgaaca tcttgccgat tatgaacacc
    10021 gcggcgatcg ccacggccac aaagatgttg ttcatgatca gccagggatc tatcagcaat
    10081 ccgatggaga tgaagaacag ggccatgaac atctccttga tgggcgtgat ccgttcgacg
    10141 atcttctcct gggctacgga ctgggatatg attatgccaa ccaggaacgc cccgatggcg
    10201 accgacagcc cgaagaaata ggccactatg gccattccga agcacatgcc cagagagact
    10261 atcagcagcg tttccggcga ggacacgggg tacatgcggt ccatcagttt cgggagcacc
    10321 gccaatccca acaccagaag tatgatcatg aacgccccga tgtaggccac ctggaggacg
    10381 atggtggtga tggtgacacc gtccccggcg gccaacgggg atgccaaggt cagaatgatt
    10441 accgcggcga tgtcctcgat tatcaatatc ccgacgatgg cctcggcgaa ctccttgctc
    10501 atcattccgg cgtcggagag caccttgatt atcaccgcgg tggagctgat gctcatgacc
    10561 gccccaagga atatcgactg gatcggggac catcccaagg ctatcccgag gccgtagcca
    10621 agggtgatca tcagaacgat ctccacgctc ccggccaggg cggcgaagag gccgaccttc
    10681 ttcaggcggc gcagattgaa ctccagtccc agggtgaaca tcagaaggac tataccggcg
    10741 ttggccaggg cgtttatggt gtccaggtcg gtaacgaagg acggctcgaa gaggttgggt
    10801 cctaggatca tccccgcggc cagatagcct atcaccactg gcaaacgtag cttggagaaa
    10861 atgacggaga tcactccagc ggtgaccatg atgatggcca tttccagcag gaatgtggtt
    10921 tccgacacca tcaacgcgcc tcagaagaac gtctgaccca catccttcgt gacggtattt
    10981 ttcctttcgc ctattttggc gttagattcc tccacgtatt cctcataaag gtgcaccttg
    11041 caggggatcg cgaacggggt gaacggagag gcgatgagcg cttcgccggg catcagcatc
    11101 tgtatctcgt tgtcaagcat ggagatgtcc tgcttggccg agttcctcag gatatctcga
    11161 tcacgcttgt ccgccagccc caggatgaac agggtgttga actgcgatat gatctcctcn
    11221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng gcgcttatga ccgccctggt
    11341 catgctcagg ttgtggtcgg tggtgacgag atcgaactgg aatatggagt ccaggcggcg
    11401 cttgatgacg ttcacgctgc cctcatggaa ccggccgttc agatcggtga ctatggtggc
    11461 cacgctcttg tcccggagct catcgagcca tttctctcca tacttccatt gggaggcctg
    11521 caggcattcc agctgggggc cggagaactc gtagaggttc gccaggtccg ggatctcgat
    11581 ctccgagctg gatatgtgga tggaactgtg cggcccgtcc agtcggcggg aggaatagac
    11641 gtccaaggcc tccggggcca gcttggagtg cgacaatcct ttctttccgc gctccccgcc
    11701 atcgaaatat tctccatgcg gatcgaggat caggaaaccg cagcgccggg actccatgca
    11761 ggatagcgcc aacgatttca tcagattgct cttgcccatg ccggtggtgg cgaagatccc
    11821 cacatggtgc gggaatccgc gcgaatcgat tcctacccgg aagtccagga cgcgatcgcc
    11881 ggaccgaaga cggccgacct ccacgtcccc catcaatggc ttcaggaaat cgtaatcgtc
    11941 ctggtccgcg cggcgaacgc gggagaagtg cctgggtatg gacttcgcct tccggtatcg
    12001 gctatccttc aagcagccca ggggggtgca gacgcccacc ttgtaaaggt cgcccttgat
    12061 gcgctcgtaa tcgaagccat ccttcaaggc cactccagcc tgccattcca gataatcgtc
    12121 atcgtccgaa tcggcgccga acagcacgtc catggtccgc acgaggaact tgacgccgcc
    12181 ctcttcgaca accagcatct ccccgacctg caggtcctcc gcctcactgg tgcggaagcg
    12241 cagttccatg accttgttgc cgaaaatcct gccaatgtcc gtcatgatgg ccgcccatag
    12301 cctccgaggg gtatagaaat ttctgcgggt acggtgaaaa tgccatatct aatgaagttg
    12361 ttaatgagtt cgtgcgacca gacataatcg agcttccagc ccaatcaacg ctaccccgac
    12421 cggaggtact ggtcgttggc gtgggtgggg cgggaaggca tatggccgcg caaatgcctg
    12481 gcaacaaggt cgccgttagc ttggagggtg atgctgggat accgggtcac cgtcaggtgc
    12541 tccttcggaa gggggaggtc accgtcgccc gaaccagctc ccccaccgcc ctgcacgttt
    12601 ccgacctccc gtggaagaat cggctgctgg aggcggtggg aaggccggag gtgctcttcc
    12661 tgttcagtgg gctgggcggg gagaccggta gctacatagc tccgctgatc accgaactgg
    12721 cacattacac gaccatgacc ttcgccagcg tctgccttcc cttctcggtg gaaggctcca
    12781 accggcgggc catggccaag gaggggctcg tgcggctcaa ggcggcatcg cacatggtgg
    12841 ccgtttacgc caacgatcca ttgatcaagc tggctccgaa cctgcctttg agcaaggcct
    12901 tcggggtcat ggaccacatc atgctatccc tgccgaccga cctctgccaa tgcctgacgg
    12961 ccgaggcgat gccgttgctc aaggagaaca tgggtagaaa agagctacgg gcgggcatcg
    13021 gctacggcct gggcctggag agggagcggc tggcggtgga ggacgccctc acctccccct
    13081 ggttcccctc ggccgagttc cagccggaca ccgccctgat gctggtcacc ctgggacagg
    13141 aggaccgaat cagcacggac gactgcgtga aggagatgtc cgaacggctt aaggttagga
    13201 agctgctggt cgcctctcat gtcgacccgt ccctcggccg ccgggtgaag gtctcccttc
    13261 tgttaggtta cagcttctga tcgtcggcga tctcctcggg agccccggcg aactt
//
LOCUS       DAOPZI010000036        12629 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_5550_length_12629_cov_9.689359, whole genome shotgun sequence.
ACCESSION   DAOPZI010000036 DAOPZI010000000
VERSION     DAOPZI010000036.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 12629)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12629)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12629
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5550_length_12629_cov_9.689359"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..593)
                     /locus_tag="PKM11_06945"
     CDS             complement(<1..593)
                     /locus_tag="PKM11_06945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HNX48275.1"
                     /translation="MKLYRVGKVKKVFEVDDSTFEFHFTNNISVFDKIIPTEIPHKGE
                     VLCRISAYWFKLLEEHGIRSDFIKLSGKDRMLVKRVNVIPDYSKLNSKTTNYLIPLEF
                     ICRHYNAGSLNDRVKEGKITVEQLGFPKGHQLKYGEKLPRPYLEATTKLEETDRNLTD
                     EEAKRISGLTDKEYHEVFDTIAKIDALIGERAKKAGL"
     gene            complement(630..1328)
                     /locus_tag="PKM11_06950"
     CDS             complement(630..1328)
                     /locus_tag="PKM11_06950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KaiC domain-containing protein"
                     /protein_id="HNX48276.1"
                     /translation="MGIEKVKTGMEGLDEMLFGGIPKGSTVVVMGSFGTGKTTFGLQF
                     LNQGLAEGEKGIYISLEEDRESILADAEAHGWDLRAKLNEKKLEIVKLEPNDAKVTIQ
                     RIKSELPEFIKKFGASRIVVDSVSLLNLLFDNDHDRRTNLFNLSQMVKKTGATLLMTA
                     EVKDDNPFASRDGLVEYVADGVISLRYLEMQSRNELMLSIRIIKMRRTEHSRKITPYS
                     ITNKGLEVHVGSEF"
     gene            complement(1328..2170)
                     /locus_tag="PKM11_06955"
     CDS             complement(1328..2170)
                     /locus_tag="PKM11_06955"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48277.1"
                     /translation="MDATVKRIPSGVSDFDSIVKGGIPQGSVILLMGDLGAGQQEYAL
                     TSASKISLVKENPNVSDYYLGHRIGQRVMPKKICYVTFARSQEDILQEIRVSFNEDFY
                     GAFERNVIFKDFSKQYFRNTLVPRSWTGEASSGLFSDDGEQNTLEALVDYLDANAHDS
                     MIIIDSLTDLVVNNQIEEVDLVAVMRGMQRMAKRWKGVIYLLLTKDIVDARKEKLIMD
                     SVDGALVFEWSKFAQSSRRQRYMYVEKFMSILPHLDQQRIARFATIVTAQHGLVVIDT
                     ERIS"
     assembly_gap    2228..2327
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<2328..2578)
                     /locus_tag="PKM11_06960"
     CDS             complement(<2328..2578)
                     /locus_tag="PKM11_06960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48278.1"
                     /translation="MEKGNKAWSAILTIIITIVVISTAYLASGMLHDRLVPEEDDPVA
                     VVTLVSINTVGLGGTGEHPQLPVTWSSVGDYDVGVKVTGL"
     gene            complement(2628..3095)
                     /locus_tag="PKM11_06965"
     CDS             complement(2628..3095)
                     /locus_tag="PKM11_06965"
                     /inference="COORDINATES: protein motif:HMM:TIGR00199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CinA family protein"
                     /protein_id="HNX48279.1"
                     /translation="MLETDVLYQLRRAGLTLAVAESCTGGRICDRLTDVPGSSEHFKG
                     GIVAYSNDSKVRFLDVSRDTLKEHGAVSEETAKEMAAGVAKAFDADIGISVTGIAGPG
                     GATPQKPVGLVYVGLAWKKERLAFKFLFDGDRKSVKAQATEQALQQVLNFIPL"
     gene            complement(3082..3624)
                     /locus_tag="PKM11_06970"
     CDS             complement(3082..3624)
                     /locus_tag="PKM11_06970"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000309 - nicotinamide-nucleotide
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide adenylyltransferase"
                     /protein_id="HNX48280.1"
                     /translation="MSDVNRVDCLLIGRFQPFHLGHLEVVRKIAKECDELIIGIGSAQ
                     ISHTFDNPFTAGERHLMISRALREDGIKDFFLVPIVDLNQYGVWVSHVRSMVPPFQRV
                     YTNNPLTKRLFTEAGYEVSASPMFNRSQYSGTEIRRRMMEGDDWREYVPKAVASVIDS
                     IDGVKRMRDLAVQGGADAGD"
     gene            complement(3693..5657)
                     /gene="lonB"
                     /locus_tag="PKM11_06975"
     CDS             complement(3693..5657)
                     /gene="lonB"
                     /locus_tag="PKM11_06975"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease LonB"
                     /protein_id="HNX48281.1"
                     /translation="MEQDVKENAVKIPDVETWIGTQSFTSTADIKIPEKLSDQVIGQD
                     SAVEVVRKAAEQKRHVMLIGEPGTGKSMLAKSMTEYLPKDDLQDVIAYHNPDDPNEPR
                     IRTVPAGKGKEIVSAQKREAMARKSKKSSMITAIVMMVMVLTVVLYWSGGAKDPMILL
                     FGIMAAAMIFFATRYVGQRQENFMIPKLLITHEEGSTIPFIDATGAHAGSLLGDVKHD
                     PFQSGGLETPAHERLEVGAIHKASKGILFVDEINMLRMESQQSLLTALQEGKFSITGQ
                     SERSSGAMVKSEAVPCDFVLVCAGNMDAMQGMHPALRSRVRGYGYEVYMRSTMDDTEE
                     NRAKLVRFVAQEVAKDKKIPHFDKMAVMEIVKEAQRRAGRRGQLTLRLRELGGLIRVA
                     GDIATEESAPIVTQEHVTKAKRVARSLEQQIVDRYIQAHKLYPSFNTEGGAVGIVNGL
                     AAMNSSSSMSELSGIVLPIVAEVTPAQTKNGGQIIATGKLGEIAKEAVQNVSAIIKKY
                     TGEDISNHDVHVQFIGTYDGVEGDSASISIATAVISALEDVPVDQTVAMTGSLSVRGQ
                     VLPVGGVTAKIEAAAESGLKKVLIPKANQFDVVLEERYIGKIEIIPVTNMGEVLSHAL
                     INGSKKDGLLQKLAALVSAPLKPAAKPIVQ"
     gene            complement(5818..6357)
                     /locus_tag="PKM11_06980"
     CDS             complement(5818..6357)
                     /locus_tag="PKM11_06980"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX48282.1"
                     /translation="MKDVKMPRCSVVPLIDKEQIAGFESSNDELTAYLHEEALRDQSL
                     LLATTHLLVDETGSTLGYLSLLTDSIKVKVIGDHPGISGIEYASIPALKIGRLTCRRG
                     YEGKGLGTEMIRLALSYLFEIVKYSGCRIMTVDSKKGCEGFYELLGFKKTTINKHYFT
                     PMYLDVIYFLDTSNYMRVL"
     gene            6653..8899
                     /locus_tag="PKM11_06985"
     CDS             6653..8899
                     /locus_tag="PKM11_06985"
                     /inference="COORDINATES: protein motif:HMM:NF012492.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HNX48283.1"
                     /translation="MSDWKSMLPPKVLEILAEDGITSLYPPQEKAVPLVLQGKNLVLA
                     VPTASGKSLVAYLAAVKRVLEDHGKVLYIVPLKALAAEKLEELKRFEQLGIRVGMSIG
                     DYDDGDRDLDRLDVLVATSEKADAIMRHRPDWVRSMSLVIADEVHLMNDPNRGPTLEI
                     TLTKFRMLNPKLQVIALSATVGNSKEMAKWLDAEHVATNWRPVKLKEGVLLEDTINFT
                     DNTHRKVKRLDDQVWSLVKDTIDEGGQALVFVNTRRSTETLAVKFARLVKDRPDEEVE
                     KQLKEGFRDEHTSIGLSLRDCMRNGMAFHNAALSGEHRTLVEKLFKAGKIKCIVATPT
                     LAAGINLPARRVIVRDVNRFDDGGYVPLPVMEVKQMCGRAGRPRYDPYGEAVLLAKTV
                     EQSHMLFENYLLGEPEDVISKVGSERVLRAHVLALIATDTSNTRKAILDFLRRTFYAH
                     QRGEQGMEEAVDNIVRFLWEEGFIRCPGTEMLALELEADLKATFFGRRVSDLYIDPMS
                     AVKLRDGLLAYVPGEKTLGFLHAVCSTPDMLNLYLKRDDFDHLTEVVLERKEEMLFMV
                     PDMETPDYEYFLAEVKTALVLDAWIAETDEEEMHRAFGTGPGDIHNKVEIGEWLLYSM
                     REMSNIFNKDCYPILTKLMTRMRYGVREDLLELVELKGVGRIRARSLQKRGFTSWETI
                     KEADVHAISAVTGIGDTLAERIKKQVDPDFVPSKPAKPRTAKEERPPVKNEPNVPSKK
                     GQSKLFDF"
     gene            complement(8896..9912)
                     /locus_tag="PKM11_06990"
     CDS             complement(8896..9912)
                     /locus_tag="PKM11_06990"
                     /inference="COORDINATES: protein motif:HMM:NF014691.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HNX48284.1"
                     /translation="MSHVVFPARLERRRTSKGQLQFFLAKDVRVGDRKAKVTKYLGTE
                     EPSLGELERALVAAAYDLERKALEKRAELSSSRYSSLPFGPQEGTIIVQMLERFRSLH
                     RSLSENLRPDEMRETEESLEHRYVNGSTGIEGNTLTLQETRLLLQEGIVPEGRSLREI
                     NEVQNYLAVRVFRERHHGRLTLSTIKKIHYLIMSNIEGSAGTLRRTDDIGIVGRDLLL
                     TPSIMIEEELTSALDEYYGSLERGTHPFFAAVLFHHQFESVHPFTDGNGRVGRELFNI
                     MLESNGFPRVPFASGERQRYLRALTKGDDGDVKGMIEVFMRMMMEQRTDVAMEALKRL
                     TSGD"
     gene            complement(9979..10926)
                     /locus_tag="PKM11_06995"
     CDS             complement(9979..10926)
                     /locus_tag="PKM11_06995"
                     /inference="COORDINATES: protein motif:HMM:NF020419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HNX48285.1"
                     /translation="MSDVPGKTYFSRLVGRTGFKADSLEKVYRLMMILDRMQTVPELS
                     NNLALKGGTAIQGMVFGFKRLSVDIDLNYIGDIDRTIMQKDRAEIRRSLLLLFKDLGY
                     KADAPVSMYAEEQFDIHFRNCGGGADHLKLEINYLERMPVAGTIEGELKHPFEDLGSV
                     KAITYRPEELFAGKMRALIIRGTPRDIYDANMIFSTVQAIDSSLFRKLVLFYLSMYGD
                     ARSMGTGAVESVTEKDMLNNLVPMLPRTSSIDAVALRGDALSFARDLLTLSQREKDFF
                     QAMYSEKRIDQNLLFEHLQVHKALHLHPSIVWKLRSIKP"
     gene            complement(10919..11710)
                     /locus_tag="PKM11_07000"
     CDS             complement(10919..11710)
                     /locus_tag="PKM11_07000"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48286.1"
                     /translation="MNQKGCGGQREIYMTALRGQFITTDEALRIACTESTARMALWRL
                     TTKGNLVRVREGLYAAVPPEHAGSEYEFDRYLLADRAMDRTGALAFHSALELHGAVNS
                     QFTTVYYLSVKKFKPFDFQDIFYRPVLASKLFGMTVHYVDDIPINVTDRERTFLDCIR
                     RPDLCGGVEEYLKSMEAFALMDQHKILKYLERFDEKGLYHKAGFILSYLKDRIRVSED
                     LLESLRGKVGPNVTYLVPGRKAGGRLVKEWNVLVPGNIEEMVRFV"
     gene            complement(11958..>12629)
                     /locus_tag="PKM11_07005"
     CDS             complement(11958..>12629)
                     /locus_tag="PKM11_07005"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HNX48287.1"
                     /translation="NGLDENLSGGIPKGNIIMVSGAAGTMKSSLAYYILHQNAVREGV
                     KALYISLEQNKPSLMRQMEYLRMPGNPDGLVEVLDLGEIRLQAQSGGWFDTFRFAVEE
                     SKKRMNYDILVIDSLGALELIAKFEQPREEIFRLFEWLRSTEVTTFMIAEMPVGQYQY
                     YGSSDTDFLADGIIHLKMVEVGDIEVQRRLRVVKMRETDHSSSYFSFYFKEGTFYVTR
                     AITDF"
BASE COUNT         2628 a         3616 c         3424 g         2861 t
ORIGIN      
        1 atgagcccgg ccttcttcgc ccgttcgccg atgagcgcgt cgatcttggc gatggtgtcg
       61 aagacctcat ggtactcctt atcggtgagg ccggagatgc gcttggcctc ctcgtccgtg
      121 aggttgcggt cggtctcctc cagcttggtc gtcgcctcca agtacggtcg gggaagcttc
      181 tcgccgtact tcagctggtg ccctttcgga aagcccagct gctctacggt tatcttgcct
      241 tccttcaccc ggtcgttcag ggagccggcg ttgtaatgcc ggcagatgaa ctccagcggg
      301 atgagatagt tggtggtctt gctgttcagc ttggagtaat cgggaatgac gttcacccgc
      361 ttcaccagca tgcggtcctt gccggataat ttgatgaagt ccgagcggat gccatgctct
      421 tccagcagct tgaaccagta cgccgagata cggcagagaa cctcgccctt gtgcggaatt
      481 tcggtcggga ttatcttgtc gaagacggag atgttgttgg tgaagtggaa ctcgaacgtg
      541 ctgtcgtcga cctcgaagac cttcttgacc ttgccgaccc ggtagagctt catcgctaga
      601 gtgatgacgg aacgatgaat aaagtttgct cagaactcgg aacccacgtg cacttccagg
      661 cccttgttgg tgatcgaata tggcgttatc tttcgggagt gctcggtcct cctcatcttg
      721 atgatgcgga tcgacagcat cagctcgttg cgggactgca tctccaggta acgcaacgat
      781 atcaccccgt ccgcgacgta ctccacgaga ccgtcccggg aggcgaaggg attgtcgtcc
      841 ttgacctcgg cggtcatgag cagtgtggct ccggtcttct tgaccatctg ggacaggttg
      901 aacaagttcg tccgtcggtc gtggtcgttg tcgaacagca agttcaacag agagacggaa
      961 tcgacgacta tgcgggaggc cccgaacttc ttgatgaact cgggcagctc gctcttgatg
     1021 cgctgtatcg tcaccttagc gtcgttcggc tccagcttga cgatctccag cttcttctcg
     1081 ttaagcttgg cgcgcaggtc ccagccgtgc gcctccgcgt cggccagtat cgattcccgg
     1141 tcctcctcca atgatatgta tatgcccttt tccccttccg ccagtccctg gttgaggaac
     1201 tgcagaccga aggtggtctt accggtaccg aaggaaccca tgaccaccac cgtggatccc
     1261 ttggggatgc ctccgaacag catctcgtcc agaccctcca ttcccgtctt gaccttctca
     1321 attcccatca cgatatcctc tccgtgtcta tgaccaccag tccgtgctgc gcggtcacga
     1381 tggtggcgaa cctggctatg cgttgctggt ccaggtgcgg cagtatgctc atgaacttct
     1441 ccacgtacat gtagcgttgt cgacgggacg attgggcgaa cttgctccac tcgaacacca
     1501 acgccccgtc caccgagtcc atgatcagct tctccttcct ggcgtccacg atgtccttgg
     1561 tgagcagcag gtagataact cccttccagc gcttggccat gcgctgcatg ccgcgcatca
     1621 ccgccaccag gtccacctcc tcgatctggt tgttcaccac caggtcggtc agcgaatcta
     1681 tgatgatcat gctgtcatgc gcgttagcat ccaggtagtc caccaaggcc tcgagcgtgt
     1741 tctgttcccc gtcgtccgag aacaacccgg aggacgcctc gccggtccag ctccttggga
     1801 ccagcgtgtt gcggaaatat tgcttggaga aatccttgaa gatgacattt ctctcgaacg
     1861 ccccgtagaa gtcctcgtta aaggagaccc ttatctcctg caggatgtcc tcctgggagc
     1921 gggcgaacgt tacgtaacag atcttcttgg gcatgaccct ctggcctatt cggtgcccta
     1981 ggtagtaatc ggaaacgttg gggttctcct tgaccagtga tatcttggaa gccgaggtca
     2041 acgcgtactc ctgctggccc gcgccaagat cgcccatgag cagtatgacc gagccttggg
     2101 gtatcccacc cttgactatg ctgtcaaaat cggacacacc gctggggatc cttttcactg
     2161 tggcatccat tcccgcacct gactgggcat ttatagggat atgaccttat aattgtatgg
     2221 tggcctgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnagc ccggtcacct
     2341 tgaccccaac gtcataatct cccacggagc tccacgtcac aggcagttga gggtgctcgc
     2401 ccgtgccgcc gaggccgacg gtgttaatgg agaccagggt caccacggcc actggatcgt
     2461 cctcctcggg aaccaggcga tcgtgcagca tgccagaggc caggtaggcg gtggatatca
     2521 ctacgatcgt gatgatgatc gtcaggatcg ctgaccaagc tttattgcct ttttccacct
     2581 tcgcgccccc tactaaatta tttcctatgg atataattaa ttccccttta taagggtatg
     2641 aagttcagga cctgctgcaa ggcctgctcg gtggcctgcg ccttgacgct cttccggtcg
     2701 ccgtcaaaga ggaacttgaa agccaggcgc tccttcttcc aagccagccc cacgtagacc
     2761 aggccgaccg gcttttgcgg cgtggcgcca cccggtcccg cgatcccggt gactgaaatg
     2821 ccaatgtccg cgtcgaaggc cttggccacg cccgccgcca tctccttggc ggtctcctcg
     2881 ctcaccgcgc catgttcctt caacgtatcg cgagaaacgt ccaggaacct gaccttggaa
     2941 tcattgctat aggcgacgat gccgcccttg aaatgctccg atgaccctgg aacatcggtc
     3001 aagcgatcgc atattcgccc accggtgcag gattccgcca cggccagggt caacccggcc
     3061 cttcgcaatt ggtaaaggac gtcagtctcc agcatcggcc ccaccctgga cggccaggtc
     3121 ccgcatgcgc ttgaccccgt cgatggaatc gatgacgctg gcgaccgctt ttggcacata
     3181 ctcgcgccaa tcgtcccctt ccatcatccg cctgcggatc tccgttccgg agtactggga
     3241 gcggttgaac atcggggatg ccgacacctc gtatcccgcc tccgtgaaga ggcgcttggt
     3301 caacggattg ttcgtgtata ccctctggaa cggaggtacc atggaccgga cgtgcgagac
     3361 ccataccccg tactggttga ggtccacgat aggcaccagg aagaagtcct tgatgccgtc
     3421 ctcccgcagg gcgcgggata tcatgagatg cctttctccg gcggtgaacg ggttgtcgaa
     3481 ggtgtgggat atctgagcgc tgccgatgcc tatgatgagc tcgtcgcatt ccttggctat
     3541 cttacgaaca acctccaggt ggccgaggtg gaacggttgg aatcgaccga tcaataggca
     3601 gtccacgcga tttacgtcgc tcataacgcc aggtcaatcc ggttctgccg ataaaaccct
     3661 tgtcctaaaa aaaaatggaa aaagtaaggg gtttactgga cgatcggttt cgccgccggc
     3721 ttcagcggag cgctgaccag ggcggccagc ttctgcagca gaccgtcctt cttgctcccg
     3781 ttgatgagcg cgtgcgagag cacctcgccc atgttggtca ccggtatgat ctcgatcttt
     3841 ccgatgtagc gctcctcgag caccacgtcg aactggttgg ccttgggtat caggaccttc
     3901 ttcagccccg actccgcggc cgcctcgatc ttggcggtga cgccgccgac gggaagcacc
     3961 tggcccctga cgctcaggga accggtcatg gccaccgtct ggtccaccgg cacatcctcc
     4021 agggcggaga tgaccgccgt ggcgatggat atggaggccg aatcgccctc cactccgtcg
     4081 taggtcccga tgaactgcac gtgcacgtcg tggttgctga tgtcctcgcc ggtgtacttc
     4141 ttgattatgg cggagacgtt ctgtaccgct tccttggcga tctccccgag cttgccggtg
     4201 gcgatgatct ggccgccgtt cttggtctgt gccggggtga cctcggccac gatgggaagc
     4261 acgatgccgg acagctcgga catgctgctg gaggagttca tggccgccaa tccgttgacg
     4321 atgcccaccg ctccgccctc ggtgttgaac gatgggtaga gcttgtgcgc ctggatgtaa
     4381 cggtccacta tctgctgctc gagcgagcgg gccaccctct tggccttagt gacatgctcc
     4441 tgggtgacga tcggtgcgga ctcctcggtg gcgatgtcgc cggcgacccg gatgagaccg
     4501 cccagttccc tcaggcggag ggtgagctgc ccgcgccttc cggcgcgcct ctgagcctcc
     4561 ttgactatct ccatgaccgc catcttgtcg aagtggggga tcttcttgtc cttggccacc
     4621 tcctgagcta cgaaccttac cagcttggcg cggttctcct cggtgtcgtc catggtggag
     4681 cgcatgtaca cctcgtagcc gtagccgcga acgcgggaac ggagggcggg atgcatgccc
     4741 tgcatggcgt ccatgttacc agcgcaaacc agtacgaagt cgcaaggcac ggcctccgac
     4801 ttcaccatcg cgccggagct cctctcggat tgtccagtga tgctgaactt gccctcctga
     4861 agcgcggtaa gcaacgactg ctgggattcc atcctcagca tgttgatctc gtccacgaac
     4921 aggatgccct tggacgcctt gtgaatggcg ccgacctcta ggcgctcgtg cgccggggtc
     4981 tccaggccgc cggactggaa cggatcgtgc ttgacgtcgc ccagcagcga accggcgtgg
     5041 gcgccggtgg cgtctatgaa cggtatggtc gacccttcct cgtgggtgat cagcagcttg
     5101 gggatcatga agttctcctg gcgctgacca acgtaacggg tggcgaagaa gatcatggcc
     5161 gcggccatta ttccgaacag caggatcatg gggtccttgg cgcctccgct ccaatacaga
     5221 acgaccgtca ggaccatgac catcatgacg atggccgtga tcatggagga cttcttggac
     5281 ttgcgggcca tggcctccct cttttgagct gaaactatct ctttgccctt tccggccggt
     5341 acggtacgga tgcgcggctc attgggatcg tcagggttgt gataggctat gacgtcctgc
     5401 agatcgtcct tggggaggta ctccgtcatg gacttggcca gcatcgattt gccagtgccc
     5461 ggctcgccga tgagcatgac gtggcgcttc tgctcggccg ccttgcgaac gacctccacc
     5521 gcggagtcct gaccgatgac ctggtcggaa agcttctccg ggatcttgat gtcggcggtg
     5581 ctcgtgaagg actgggtccc tatccaggtc tccacgtcgg gtatcttcac cgcattctcc
     5641 ttaacatcct gttccatgtt caccttatct caaaacaatc ccatgcaagc gctgctatat
     5701 aaacaaattc ctcgcaatca gtggaatgat tgtaaggcca gcattgattc tgaacgcgta
     5761 atgatgattg gttcgaatag cataaattat gtccattctc gaatcgttga atactattca
     5821 gagaaccctc atataatttg atgtatccag gaaatatatg acatccaggt acattggtgt
     5881 gaaataatgt ttatttattg ttgttttctt aaatcctaaa agttcgtaga atccctcaca
     5941 gccctttttc gaatcgaccg tcataatcct gcatccagaa tattttacaa tctcgaaaag
     6001 ataacttaga gccaacctga tcatttcagt gccaagtcct tttccttcgt atcctctccg
     6061 gcaagttagt ctgcctattt tcaatgcggg aatcgatgcg tactcaattc cacttattcc
     6121 gggatggtca ccgatgacct tgactttgat ggaatccgtg agcaatgaca agtaacctaa
     6181 ggtggatcca gtttcgtcaa ccaaaagatg cgtcgttgct aaaagaagtg attgatccct
     6241 taacgcttcc tcgtgtagat atgcagtaag ctcgtcattc gatgattcga agccagctat
     6301 ctgctcttta tcgatcagag gtactaccga gcatctcggc atttttacat ctttcacggg
     6361 attttgctag ctcgtatgct tccctgataa tttgcattcc ccgtaatgta caggtgggat
     6421 tcctaaggta ttctagaaaa tcaatggcat cttggccttc tagttctaaa ccaacatcaa
     6481 ttctttgagc catgacgatc cccagacgtg ctatcggttg attataattg ataactggtt
     6541 aataattcca tcgcgcagat gtagtcctcg aaccggtatt ggtgaggcta tcgcgccaaa
     6601 cgataggagc aagtgaaact gtaataaccc ctccggacat cccctatcgc ccatgtcaga
     6661 ctggaagagc atgctgccgc cgaaggtgct ggagatcctg gcggaggacg gcataacgtc
     6721 gctgtatccg ccgcaggaga aggcggtgcc gctggtcctg cagggcaaga acctggtgct
     6781 ggcggtgccg accgcctccg gcaaatcact tgtggcctac ctggcggcag tgaaacgtgt
     6841 tttagaggac catggcaagg tcctgtacat cgttccctta aaggcattgg cggcggagaa
     6901 gctggaggag ctgaagcgct tcgagcagct cgggatacgg gtgggaatgt ccatcggcga
     6961 ctatgatgac ggcgaccggg acctcgatcg ccttgacgtt ctggtagcca cgtccgagaa
     7021 ggctgacgcc atcatgcgcc accgcccgga ttgggtacgc tccatgtcct tggtcatcgc
     7081 ggacgaggtg cacctgatga acgaccccaa ccggggtccc acgctggaga ttaccctcac
     7141 caagttccgc atgctgaacc ccaagctgca ggtgatagcg ctctccgcga cggtgggcaa
     7201 cagcaaggag atggccaaat ggctggacgc cgagcatgtg gccaccaact ggcgcccggt
     7261 caagttgaaa gagggcgtgc tgctcgagga caccatcaac ttcacggaca acacccatcg
     7321 caaggtgaag cgcctggacg accaggtgtg gtccttggtc aaggatacga ttgacgaagg
     7381 aggtcaggcg ctggtgttcg tgaacactcg acggtccaca gagaccttgg cggtcaagtt
     7441 cgcccggctg gtcaaggaca ggccggacga agaggtggag aagcagctga aggagggatt
     7501 ccgggacgag catacctcga tcggcctgtc gctcagggac tgcatgcgga acggcatggc
     7561 cttccacaat gccgccctca gcggcgagca tcgcacgctc gtggaaaagc tgttcaaggc
     7621 cgggaagata aagtgcatcg tggccacgcc gacgctggcg gcgggaataa atctcccggc
     7681 caggcgggtg atcgtcaggg acgtgaaccg cttcgacgac ggcggttacg ttccgcttcc
     7741 ggtgatggaa gtcaagcaga tgtgcggccg ggccggccgt cctcgttacg acccgtacgg
     7801 cgaagcggtg ctcctggcga agaccgtcga acagagccac atgctgttcg agaactatct
     7861 tctgggcgag ccggaggacg taatatccaa ggtggggagc gagcgggtcc taagggcgca
     7921 cgtcctggcg ctgatagcca cggacacctc gaacaccagg aaggccatcc tggacttcct
     7981 gcggagaacg ttctacgccc atcagcgcgg tgagcagggc atggaggagg cggtcgacaa
     8041 catcgtgcgc ttcctgtggg aggagggctt catccgctgc ccgggaacgg agatgctggc
     8101 cctggaattg gaggccgatc tcaaggcgac cttcttcggt cgacgagtct cggacctgta
     8161 cattgacccc atgtccgccg taaagttacg cgatgggttg ctggcctacg tcccgggaga
     8221 gaagacgctg ggattcctgc acgccgtgtg ctccacgccg gacatgctca acctttacct
     8281 caagagggat gacttcgatc atctgacgga ggtcgtgctg gaacggaagg aggagatgct
     8341 cttcatggtc ccggacatgg agacacccga ttacgagtac ttcctggccg aggtgaagac
     8401 ggcgctcgtt ctcgatgcgt ggatagccga gacggacgag gaggagatgc accgggcctt
     8461 cggcaccggt ccgggggaca ttcacaacaa ggtggagatc ggcgaatggc tcctctactc
     8521 catgcgcgag atgtccaaca tcttcaacaa ggattgctat ccgatcctga ccaagctcat
     8581 gacccgcatg cgctacggcg tgcgggagga cctgctggag ctggtggagc tgaaaggggt
     8641 cggccgtatc cgcgcccggt ccctgcagaa gagggggttc acctcctggg aaacgataaa
     8701 ggaagctgac gttcacgcca tatcggccgt caccgggatc ggcgacacgt tggcggaacg
     8761 aataaagaag caggtggacc cagatttcgt gccgagcaag cctgccaagc cgagaacggc
     8821 gaaggaagag agaccgccgg taaagaatga accgaacgtg ccttccaaga aggggcagag
     8881 caagctgttc gacttctagt ccccggacgt cagacgctta agggcctcca tggccacgtc
     8941 cgtcctctgc tccatcatca ttctcatgaa cacctcgatc atccctttca catcgccgtc
     9001 gtcccctttg gtcaaggccc tgaggtaacg ttgcctctcc ccgctcgcga atggcactct
     9061 agggaacccg ttcgattcga gcatgatatt gaacagttca cgtcccaccc ggccgttgcc
     9121 gtcggtgaag ggatgaacgc tctcgaactg atgatggaac agcaccgccg cgaagaaggg
     9181 gtgcgtccct ctttccaacg acccgtaata ttcgtcgagg gccgaggtta gctcctcttc
     9241 gatcatgatg gaaggggtga gcagcaggtc cctgcccact atcccaatgt cgtccgttcg
     9301 tcttagagtt ccggcggaac cttcgatgtt tgacattatc aggtagtgta tcttcttgat
     9361 cgtggacagg gtgaggcgtc catgatgcct ctctcggaac acgcggactg ccaggtagtt
     9421 ctgtacctcg ttgatctccc tcaatgaacg cccctcggga acgatgcctt cctgcagcag
     9481 cagtcgagtc tcctgcaagg ttagcgtatt tccttcgatt cccgtgctgc cgtttacgta
     9541 acgatgctcg agcgactcct ccgtttctct catctcgtcc ggacggaggt tctccgatag
     9601 cgaacgatgc aaggaacgga aacgttccag catctgtact atgatcgtac cttcctgagg
     9661 accgaaaggt aaagaggagt atcgggaaga actgagctcg gctcttttct ctagggcttt
     9721 gcgctccaga tcgtacgccg cggcgaccag agctctttcc aattcgccga gcgacggctc
     9781 ctcggtcccc aggtacttgg tgaccttggc cttcctatcg ccgacccgaa cgtccttggc
     9841 cagaaagaac tgcagctggc ccttgctcgt tcgccttcgc tccaatctcg ccgggaagac
     9901 cacgtgagac ataatgtaat ggcagatata tgaatactta ataaattgcc attacatgaa
     9961 tatatatttt ccaatagctc acggtttaat tgatctcaat ttccacacga tagatggatg
    10021 caggtgtaac gctttgtgaa cttgcagatg ctcgaacaga aggttctggt cgatgcgttt
    10081 ctccgaatac atcgcctgaa agaaatcctt ctcccgttgc gacagcgtta acaggtccct
    10141 ggcaaaagat aaggcatctc ctctcaatgc caccgcgtct atcgaggacg tacgagggag
    10201 cattggtaca agattgttga gcatgtcctt ttcggtcacg ctctccaccg ctccggttcc
    10261 catactgcga gcgtcgccat acatcgaaag gtagaagagg acgagcttgc ggaatagaga
    10321 gctgtcgatt gcctggaccg tactaaagat catgttggcg tcgtaaatgt cccggggagt
    10381 cccacggatt atcagcgcac gcatctttcc tgcgaaaagc tcctccggcc ggtaggttat
    10441 cgcttttaca gagcccaggt cctcgaaagg atgtttaagc tcaccctcga tggttcctgc
    10501 gacaggcatc ctttccaggt aattgatctc caatttcagg tgatcagcac cacccccaca
    10561 gttcctaaaa tgaatatcga actgttcctc ggcatacatc gacaccggcg catcggcctt
    10621 ataaccgagg tccttgaaaa ggagcaataa tgatctcctt atctccgccc ggtccttctg
    10681 cataattgtc cggtcaatat ccccgatata gttcagatcg atatctacgg agaggcgttt
    10741 gaaaccgaat accataccct gaatggcggt ccctcctttc aaggccaagt tgttggatag
    10801 ttccggtacg gtctgcattc ggtcgaggat catcatgagc cgatagacct tctccaagga
    10861 atccgccttg aaaccagttc gaccgaccaa tcgggagaag taagttttac ctggaacatc
    10921 agacaaaacg aaccatctcc tcaatattac caggaactag gacgttccat tcctttacta
    10981 agcggcctcc agccttcctc cccggtacca ggtaggtgac gttgggtccg accttgcccc
    11041 tcaaggattc caggagatcc tccgacaccc tgatcctgtc ctttagatag gataggatga
    11101 aaccggcctt gtggtacaac cccttctcat cgaaacgttc cagatatttc aggatcttat
    11161 gttggtccat cagggcaaat gcctccatgc tcttgaggta ctcctccacc ccaccgcaca
    11221 ggtccggccg gcggatgcag tccaagaagg tcctttcccg gtctgtgaca tttataggaa
    11281 tgtcgtccac gtaatgtacg gtcatgccga atagcttgga ggccaacacg ggccgataaa
    11341 aaatatcttg gaaatcgaag ggtttgaact tcttgaccga tagataatag accgtcgtga
    11401 actgcgagtt gacggcgcca tgaagttcaa gggcgctgtg gaatgccagg gcaccggtcc
    11461 tgtccatggc cctgtcggca agaaggtagc gatcgaactc atattcagaa ccagcatgtt
    11521 ccggtggaac ggccgcgtac agaccttctc ggaccctgac caaatttcct ttcgtggtca
    11581 aacgccatag agccattctt gccgtgctct cagtgcatgc gatacgcagc gcttcatctg
    11641 ttgtgatgaa ctgaccgcgc aaagcggtca tgtatatctc cctctggccg ccgcaccctt
    11701 tttgattcat ggctcggacc tttcgccctt gatgacgata actcatatca cctctatcgg
    11761 aaatatagtt tactatattc tgctgtatat ctaccattat gtagattcat ataactttat
    11821 aacaaataaa tgactctcat aatcacgtga cagatcaagc aggagtgcga tgagatctga
    11881 gagatggcct taacattacg accatcatga tctatcaaca gatattctgc gacatcgatg
    11941 atgccgatcg aagacgttca gaagtcggtt atggccctgg tgacgtagaa cgtcccttcc
    12001 ttgaagtaga acgagaaata actggaactg tggtccgtct cgcgcatctt gaccacccgg
    12061 agacgcctct gcacttcgat atcgccaact tccaccatct tcaggtggat tattccgtcc
    12121 gccaggaagt ccgtgtcgct ggaaccgtag tattggtact ggccgacagg catctcggcg
    12181 atcatgaacg tcgtaacctc cgtggagcgc agccactcga acagccggaa tatctcctcg
    12241 cgcggttgct cgaacttggc gatgagctcc agagcgccca gcgaatcgat gaccaggatg
    12301 tcatagttca tccgcttctt gctctcttcc acggcgaaac ggaaggtgtc gaaccacccg
    12361 ccggactgag cctgcagacg tatctcaccc aggtccaata cttccacgag gccgtcgggg
    12421 ttgccgggca tgcgcagata ttccatctgc cgcatgagcg agggtttatt ctgctccaac
    12481 gagatgtaca gcgccttcac gccttccctc accgcgttct gatgaaggat atagtacgcc
    12541 agagaggact tcatcgtgcc agccgcaccg gacaccatga tgatgttgcc cttcggtatg
    12601 ccgccggaca ggttctcgtc cagaccgtt
//
LOCUS       DAOPZI010000037        12603 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_5565_length_12603_cov_8.703857, whole genome shotgun sequence.
ACCESSION   DAOPZI010000037 DAOPZI010000000
VERSION     DAOPZI010000037.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 12603)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12603)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12603
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5565_length_12603_cov_8.703857"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..450
                     /locus_tag="PKM11_07010"
     CDS             <1..450
                     /locus_tag="PKM11_07010"
                     /inference="COORDINATES: protein motif:HMM:NF018076.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HNX48288.1"
                     /translation="DMFSGVGPFAIMIAKLSRPGVVYAIDLNPEAVQLMRENVELNKA
                     EGVVPLEGDARQWVFDLPCADRVIMNLPHSAIDFFADALTRLKLGGVMHLYHICDRND
                     FPQVLEDLKQMAFGMNVQLEVLRSEELKTYSPSSSVYSADLLLVGWL"
     gene            complement(427..915)
                     /gene="dcd"
                     /locus_tag="PKM11_07015"
     CDS             complement(427..915)
                     /gene="dcd"
                     /locus_tag="PKM11_07015"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009394 - 2'-deoxyribonucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HNX48289.1"
                     /translation="MCLVPDHEIESRMKDGSLVISDFNPEGLTPNGYDLRVAEARLEG
                     GESVTSGTFIIPPGKLFFVSTVERVELPDDLAAQLWTRTSWLRKGLLMGLGKIDAGFH
                     GTLTFSGLNASSVPVELPIGSRLVQMVLEHMHSPVERTYAKRSGNYQGQKGITLKPAD
                     QK"
     gene            1059..2045
                     /locus_tag="PKM11_07020"
     CDS             1059..2045
                     /locus_tag="PKM11_07020"
                     /inference="COORDINATES: protein motif:HMM:NF025774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MEDS domain-containing protein"
                     /protein_id="HNX48290.1"
                     /translation="MPPGEKAALFYHRLDEVCGVVAELLKDSVRQGEMCRFMFRVPKE
                     VMKERMKAHGLDLDSQPSIEIISLSQALADGYSGSSIGEQMWAFVQKAKTSGYAGTRL
                     ILNMPEVMAAQEPEKSGWSELEEVLEELGVTLVCLYDMASLSPGFLLRSLASYPQVII
                     DGVLCRNFYYVPSLNFPQRDASRDLYEQLEVIREERDIRQNEGRERSKLMESNLELQN
                     EMMQRRMAEFALLRAENNLRTMLDAMSDSVFMIDRDMRVTIANNTFVRYLGEMRLDTS
                     YEGKPIYELFPGLPVGGRRLFEEVFRYGYSTVVEESLDYQGFAGRWRCGWCQ"
     gene            2033..2497
                     /locus_tag="PKM11_07025"
     CDS             2033..2497
                     /locus_tag="PKM11_07025"
                     /inference="COORDINATES: protein motif:HMM:TIGR00229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HNX48291.1"
                     /translation="MVPVMMGDKVDRIVVISRQKTVSPDDLEAMWARAEAMKDEILNP
                     SGPSAGAMELCPHAIMVTDPEWNLISVNQAMAREFGRSKEEVLGIGNSLRFLHARRND
                     EGQVRRIDVNGRISAPSVMTRSDGSVLDVMCYVTFVEGDDRHRALTIIRPEP"
     gene            2546..2995
                     /locus_tag="PKM11_07030"
     CDS             2546..2995
                     /locus_tag="PKM11_07030"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48292.1"
                     /translation="MDHIVYLDKPAGALEAMRHGKKTMVGRAFNGRRSPYGKVKTGDM
                     LYFTENDGKQIIYGRGKVTVVYDSPKLSHDESVSLLEKHRRALWLSEAQFQRMSGKRY
                     LVLVTVDGFQDVPSFRFTRRDFHTLDDWILVGNVDNARQKGPAQGSK"
     gene            3018..3404
                     /locus_tag="PKM11_07035"
     CDS             3018..3404
                     /locus_tag="PKM11_07035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48293.1"
                     /translation="MEILAGLSVFLGAFSALLLLTMRVFPQRWARMFADAGREKGRPK
                     WAWACIALSISGIVLFWFLHFTGGTYLTLAMAVLGTFLLGRTAQSLLTKKGLRDNVQV
                     MLQGRLGAAFLPYTVASIALVVLGLL"
     gene            complement(3401..4195)
                     /locus_tag="PKM11_07040"
     CDS             complement(3401..4195)
                     /locus_tag="PKM11_07040"
                     /inference="COORDINATES: protein motif:HMM:NF013245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX48294.1"
                     /translation="MLRNVLGVKASAMVALRSQFAVVGPGLWLVQIISTALFQMWFFV
                     LVSDFANDPGATPAYVALGNAVSALTYSAVYGVTMSAGAEKHIGTMATIMSTPTRMFY
                     VFLGKGAYQSMIGLLTVTISLAFASLFFGVDLSEANLVALAAVLLATCFAMVGFGMVI
                     GSVGVYLRSSMILGSVVLYLGLLLCGVNFPISYLPEWLRPFSNVFPLTFGVQAVRDVA
                     AGAGLADVSFLVMLMIGLGVLFLALAYVLFNFFERMALKRGSLDMF"
     gene            complement(4197..4982)
                     /locus_tag="PKM11_07045"
     CDS             complement(4197..4982)
                     /locus_tag="PKM11_07045"
                     /inference="COORDINATES: protein motif:HMM:NF013245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX48295.1"
                     /translation="MIDLRAMKAALKQQSIHFFVDPQWIIPSIIAPFIFTTVTLFLFR
                     HAGGDLLIYAVLGGGVLGMWGNTIHGSSWSIGYDRMNGTLEAIMVTPAPLSSVVFGRC
                     LWNSFLGLLNALAVFLVAQFAFGIDITIQNPVGFVIALTATLISLSVLGMVFGAFYVV
                     TRASSAFFQILEFPIYVLSGAVFPLFILPEWSRPLSYVIPATWGAEALKISTLSGYDS
                     LGIGYYGALGMTVLTTMAFLLLSLWLFTLLERRAKVNGTLVRY"
     gene            complement(4979..5959)
                     /locus_tag="PKM11_07050"
     CDS             complement(4979..5959)
                     /locus_tag="PKM11_07050"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX48296.1"
                     /translation="MNGRETVIEVKDLSKVYPAAARLFGDGGKEKLAVDRVSFDVHRG
                     EIFGLLGPNGAGKTTTIKMLTTLLIPTSGSATVLGLDVVKDPVKLRPRINLVSGGERG
                     LYFRLTGKQNLEFFSDMYRVPRDVKKKKIEDLLELVGLTEAADVRVEEYSRGMKQRLH
                     LARGLVNDPEVLFLDEPTLGLDPEISRETRALIRRLSEKGMTILLTTHYMFEADELCD
                     RLAIISDGRIRAMGSPYSMKESVRNDSIIEIEARELGEAQRKELADLPGVSAVSMEFL
                     EGRQLARIVVDDAPSLIPTVAALLENRKVISIRVDQPTLEDAYIKMVSGK"
     gene            complement(5995..8601)
                     /gene="acnA"
                     /locus_tag="PKM11_07055"
     CDS             complement(5995..8601)
                     /gene="acnA"
                     /locus_tag="PKM11_07055"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HNX48297.1"
                     /translation="MAPTADSFQTKSVLELKDGPLSYYSLKKLDARTEHFPFSIKVLL
                     ESLLRQEDGILVTKEDVQKLLGWTPAGNDEVDIPFIPARVVLQDFTGVPCVVDLAAMR
                     DAVKEMGGNPSRINPLVPVDLTIDHSVQTDYHGTCYAQDLNERKEMERNLERYSLLKW
                     AQGSFNNFRVVPPGNGIIHQVNLECLATVVATRDGVAFPDSVFGTDSHTTQINGLGVL
                     GWGVGGIEAEAVMLGQPYYMPLPQVVGFKITGKLKPGVTATDMVLTAVEMLRKKGVVG
                     KFVEFYGPGIRNLSLPDRATLANMAPEYGATMGFFPVDEVTIAYLKMTGREKLCELVE
                     RYAREQGLFYEDQDPDYSDRMELDLRKVVPSLAGPKRPQDRIELSRMRSEFGKMMEKQ
                     GGKKTGNLMKDGDVLIASITSCTNTSNPSVMMAAGLLAKKAVERGLRPNPNVKTSLAP
                     GSRAVTTYLQKAGLLSYLEALGFHVVGYGCLTCIGNSGPAREDLVEDIVKNDLTVAAV
                     LSGNRNFEGRISPYVKANYLASPPLVVAYAIAGTVDLDLDTEPLGTDPNGQPVYLKDL
                     WPTAKEVKAALKKVTPAMYRKAYSTVFQGSALWDSVPAPKGETFIWDPTSTYIRKAPF
                     FDGMSKEFSPPQNIKGARALLVLGDSITTDHISPAGEFPAGSVAGQYLISLGVGEKDF
                     NSYGSRRGNHEVMMRGTFANIRLKNRMANGKEGGFTKVQPEGTLTDISTAAHQYKERG
                     VPLIVLAGKEYGTGSSRDWAAKGPHLLGVKAVIAESFERIHRSNLVGMGVLPLQFEPG
                     LTAASLGLDGSEEYDIELLEMRPRAPVMVVAYKNGKATTFKAIARLDTLVEVDYYRNG
                     GILQTVLRKLTS"
     gene            8694..10544
                     /locus_tag="PKM11_07060"
     CDS             8694..10544
                     /locus_tag="PKM11_07060"
                     /inference="COORDINATES: protein motif:HMM:NF001989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HNX48298.1"
                     /translation="MINPTEGVQDDSEENYGKHASVLRSQMRRGLIGGNTECAHFPCH
                     HPGQNCTFCFCPLYPCLDPELGEYVTSKRTGGQVWSCQNCLWIHRDDVSRSLLKMMPE
                     IGENGLDESTRSELKVKLEGVHRKRAKAIMVLGATSGAGKSLLVAALCRAFRDRGLLV
                     APFKSQNMSLNSMVTGEGEEIARIQDLQARAAGTRPRGELNPILLKPKGGVTSQVIVE
                     GRPYKDCTVQEYYSQFVPNEAPAIIARNLERLMRSNDVVVIEGAGSPAEINLRGKDVA
                     NMYVAKLARADCLLAVNIDWGGAFAYAIGTLMLLDDEERRLFKGVLINNMCPGGGSLG
                     DSLEMVKGMTGVPVLAVLPHVPSLYLPVEDSMDLDQHTAAGSGTVVAVVRLPMISNFT
                     DFDALSLEEGVRVIYARTPEDLEMADAIIVPGTKNTVQDLLWLKESGMAMAILSKTRT
                     VPILGICGGYQMLGRKIFDVHGLEGDGPSEIDGLGLLDAVTHFDSYDKRTVQVLGCLA
                     DGGEVRGYEIHMGRTEGGEEPLFRLQPDGREEGCWNRERKAMGTYMHGVFDLPAFRRF
                     FLSMIERRDAEGTNGMDHDAEIDSSLDRLAAMIEEHLDLDELLGGDVHGP"
     gene            10534..11382
                     /locus_tag="PKM11_07065"
     CDS             10534..11382
                     /locus_tag="PKM11_07065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HNX48299.1"
                     /translation="MVRRLMVQGVTSGAGKTTLTAALCRHFSTRGTDVVPFKAQNVSL
                     NSYVTRDGKEMAISQAYQAWACGLEPSAEMNPILIKPKGNGQCQIVLRGKPWKDLGPR
                     GSTPEVIDMLREQVMAAFNDNASGRELVLIEGMGSPVEMNLKDKDVSNMWLAKATRSP
                     VILVGDIEKGGVFAGLYGTYLLLDGEERDLLKGFVINRFRGDASILKEGIEELESRME
                     MPCLGVLPMVRFRAPAEDSMDLTRASGNGVGSGDVRQLWMKELDGVLEKWEGAWDLGQ
                     VRRLID"
     gene            complement(11713..12237)
                     /locus_tag="PKM11_07070"
     CDS             complement(11713..12237)
                     /locus_tag="PKM11_07070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48300.1"
                     /translation="MAHQYGGVIGGGEDIKFMYELRNEPILLSHHPLCGRFSDHLLTI
                     RGRKVCRGCITVYPTFAVMLIILLMVRPDFMVAFVGSLLLFCAQLSRFITTGRRISIF
                     FNTVLGSSLAMTVYSIIVCPLDLRILVYPFIIGVIITFEFLKGRKMRKRCKECPDRAS
                     YPQCARSVNLHHSK"
     gene            12332..>12603
                     /locus_tag="PKM11_07075"
     CDS             12332..>12603
                     /locus_tag="PKM11_07075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48301.1"
                     /translation="MDKKAIIAIILVVALVAVGTIMVLGMNPSGGEDDGPVKVIDASG
                     RPVTTNETPMRIVSCSPSLTEMVYAMGIGSHLVAVTDYCDWPADVNV"
BASE COUNT         2603 a         3648 c         3831 g         2521 t
ORIGIN      
        1 gacatgttct ccggcgtcgg gccgttcgcc atcatgatcg ccaaactatc ccgtcccggg
       61 gtggtctacg ccatagacct caacccggag gcggtacagc tcatgcggga gaacgtggag
      121 ctgaacaagg cggaaggcgt ggttccgttg gagggcgacg cccgtcaatg ggtgttcgac
      181 ctgccgtgcg ccgaccgggt cataatgaac ctgccgcatt cggccatcga cttcttcgcc
      241 gatgccttga ccaggttgaa gctgggcggg gtcatgcacc tctatcacat ctgcgaccgg
      301 aacgacttcc cgcaggtgct ggaggacctc aagcagatgg cgttcggaat gaacgtgcag
      361 ctagaggtgc tgaggagcga ggagctgaag acgtactcgc cctcctcgtc cgtctactcg
      421 gccgacctac ttctggtcgg ctggctttaa ggtgatccct ttctgcccct ggtagttacc
      481 ggaacgcttg gcgtacgttc gttcaacggg agaatgcatg tgctccagga ccatctgcac
      541 caggcggctg cctatgggca gttccaccgg gacggatgag gcgttgaggc cgctgaaggt
      601 gagcgtgcca tggaaaccgg cgtctatctt tcccagcccc atcaaaagac cttttctaag
      661 ccaagaggtc ctggtccaca gctgcgcggc gagatcgtcc ggtagctcca cccgttccac
      721 ggtcgaaacg aagaacagct tgcctggggg aataatgaac gttccggacg tgacgctctc
      781 cccgccttcc aggcgcgcct cggccacccg caggtcgtag ccattaggcg tcaggccttc
      841 cggattgaaa tcgctgatga ccagggagcc gtccttcatt ctcgattcga tctcgtggtc
      901 ggggaccagg cacataacgt ccggtatcgc gtcgcaacaa ttagaatttg cgattacttg
      961 aagaaattat taacgtgagc acaataatcc ggcgttcagt ggctggttcc aacggtatcg
     1021 ggaaaggtga tttctcttca tccaggacca ccctcgtcat gccgccgggg gagaaggccg
     1081 ctctattcta tcaccgcctg gacgaggtct gcggcgtggt cgctgaactt ttaaaggaca
     1141 gtgtccggca gggtgagatg tgtcggttca tgttccgcgt gccaaaggag gtcatgaagg
     1201 agcgcatgaa agcgcacggt cttgacctgg attctcagcc atccattgag atcatctcct
     1261 tgagccaggc actggcggac ggttactccg gctccagcat cggagagcag atgtgggcgt
     1321 tcgttcagaa ggcgaagacg tcgggatacg ccggcacccg cctgatactc aacatgccgg
     1381 aggtgatggc cgcgcaagag ccggagaaga gcggctggtc ggaactggag gaggtgcttg
     1441 aggaacttgg tgtgaccctg gtctgcctct atgatatggc ctccttatct cccggtttcc
     1501 tgctccggtc cctggcgtcc tatcctcagg tcataatcga tggcgtattg tgccgcaact
     1561 tctactacgt gccgagcctg aactttccgc aaagggacgc ttctcgggac ctttacgagc
     1621 aattggaggt catccgggaa gagcgggaca tccggcagaa cgagggccgc gaacgttcca
     1681 agctgatgga atcgaacctc gagctgcaga acgagatgat gcaacggcgg atggcggagt
     1741 tcgcgctcct gcgggcagag aacaatctgc ggactatgct ggacgccatg tcggattcgg
     1801 tgttcatgat tgaccgggac atgcgggtga ccatcgccaa caacaccttc gtccgttacc
     1861 tgggagagat gaggttggac acctcgtacg aaggaaagcc gatatacgaa ctgttccccg
     1921 gattacctgt cggggggcga aggctgttcg aggaggtgtt ccgttacggt tactccacgg
     1981 ttgtcgagga gtcattggac taccaggggt tcgccgggag atggaggtgc ggatggtgcc
     2041 agtgatgatg ggcgataagg tggaccgcat agtggtcatc tcccgccaga agaccgtctc
     2101 ccccgatgat ctggaggcaa tgtgggcgag ggctgaagcg atgaaggatg agattctgaa
     2161 cccatccggg ccctccgccg gggccatgga gctctgccct cacgctatca tggtcaccga
     2221 ccccgagtgg aacctgataa gtgtcaacca ggcaatggcc cgtgaattcg gtcgctccaa
     2281 ggaggaggta ctggggatcg ggaactccct aaggttcctg catgccaggc ggaatgatga
     2341 aggtcaggtc cggcgcatcg acgtcaacgg ccggatctcc gcccctagcg tcatgacccg
     2401 cagtgacggt tcggtccttg atgtcatgtg ctacgtcacg ttcgtcgagg gagacgaccg
     2461 ccaccgggcg ctcaccatca tccgtcctga accttgaacg atatggcaaa tctgttttat
     2521 cctttcgttg ccatcagggt gcaagatgga ccacatagtc taccttgaca agcccgccgg
     2581 tgcgttggag gccatgcgac atggcaagaa gaccatggta gggagggcct tcaacggccg
     2641 ccgctctccc tatggtaagg tcaagacagg cgacatgctg tacttcacgg agaacgacgg
     2701 caagcagata atctatggcc ggggcaaggt taccgtggtc tacgattcgc cgaagctctc
     2761 ccacgatgag agcgtctctc tgctggagaa gcaccgccgc gccctatggc tgtcggaagc
     2821 gcaatttcag cggatgtctg gaaaaagata cctggtgctg gtgacggtgg acggtttcca
     2881 ggatgtcccg agcttccgct tcacccgccg cgacttccat actctcgacg actggatatt
     2941 ggtcgggaac gtcgataatg cgcgccagaa agggccggcg caagggtcga aatgatcttt
     3001 tagaaggtga tgctcaaatg gaaatcctgg ccggtctcag tgtgttcctg ggggccttct
     3061 ccgctctcct gcttctaacc atgagggtat tcccgcaaag gtgggccagg atgttcgccg
     3121 acgccggccg ggagaaaggc cgcccaaaat gggcctgggc gtgcatcgcg ctgtccatct
     3181 ccggcatcgt ccttttctgg ttcctgcact ttaccggggg gacctacctc accttggcca
     3241 tggccgtcct gggcacgttc ctcctagggc gcaccgctca atccctcctg accaagaaag
     3301 gtctgcgcga caacgtccag gtcatgcttc agggcaggct cggagcagct ttccttcctt
     3361 acaccgtcgc cagcatcgcc ctggtggtgc tcgggctgct ctagaacatg tccagggagc
     3421 cgcgcttcaa ggccatcctc tcaaagaagt tgaacaggac gtaggccagc gcgaggaaca
     3481 ggacgcccag gccgatcatc agcatcacca ggaacgatac gtcggccagt ccggccccgg
     3541 ccgccacgtc ccggacggcc tgaaccccga aggtgagagg aaatacgtta gagaagggcc
     3601 gcagccattc cggcaggtac gatatgggaa agttcacccc gcagaggagc agccccagat
     3661 agagcaccac cgaaccgagt atcatggacg agcggaggta tacgcccacg ctgccgatga
     3721 ccatcccaaa accgaccatg gcgaagcagg tggccagcaa caccgccgcc agggcgacga
     3781 ggttcgcctc cgaaaggtcc acaccgaaga agagagaggc gaacgccaat gagatggtga
     3841 ccgtgagtag gccgatcatc gattggtacg ctcccttccc aaggaacacg tagaacatcc
     3901 gcgtcggcgt ggacatgatg gtggccatgg tccctatgtg cttctcagcg ccggcggaca
     3961 tcgtcacgcc gtacaccgcg gagtaggtca gcgccgatac ggcgttccct aatgccacat
     4021 atgcgggggt cgctcccggg tcattggcga aatcgctgac cagcacgaag aaccacatct
     4081 gaaagagcgc cgtggagatg atctggacca gccacagccc agggccgacc accgcgaact
     4141 gggagcgcaa cgccaccatc gccgacgcct tgacccccag cacgttcctc agcatgtcag
     4201 tacctcacca gcgttccgtt caccttggcc ctcctctcca ggagggtgaa gagccagagg
     4261 gacagcagca gaaaggccat ggtcgtcagg acggtcatgc ccagggcgcc atagtaacca
     4321 attcccaggg aatcgtaacc ggacaaggtg gagatcttga gagcctcggc gccccaggtc
     4381 gccgggatga cgtacgagag gggacgggac cattcgggaa ggatgaacaa ggggaacacc
     4441 gcgcccgaca ggacgtaaat ggggaactct agtatctgga agaaggcgga cgacgcccgc
     4501 gtcaccacgt agaacgcccc gaagaccatt cccaggacgg acagcgagat cagcgtcgcg
     4561 gtcagcgcga tcacgaaacc caccgggttc tgtatcgtga tatcgattcc aaaggcgaac
     4621 tgggcgacga ggaacaccgc cagggcgttc agcaacccca ggaaggagtt ccagaggcag
     4681 cggccgaaca ccacggaaga taacggggcg ggagtgacca tgatggcctc aagagtaccg
     4741 ttcatcctgt cgtagccaat ggaccagctg ctgccatgta tggtgttccc ccacatgccc
     4801 agaacgcctc cgccgaggac ggcatagatg agaaggtccc ctccggcgtg gcggaagagg
     4861 aacagcgtaa cggtggtgaa gatgaaaggg gcgatgatgc tgggaattat ccactgcggg
     4921 tcgacgaaga aatggatcga ttgttgcttc agggcggcct tcatggcccg caggtcgatc
     4981 atttcccgct caccatcttt atgtaagcgt cctccagggt cggttggtcc acccttatgc
     5041 tgatgacctt gcggttctcc agcagggccg ccacggtagg tatgagcgag ggggcgtcat
     5101 ccacgacgat gcgggccagc tgtcggccct ccaggaactc catggagacc gcggaaacgc
     5161 cgggaaggtc ggccagctcc ttccgctgtg cctctcctaa ttcccgggcc tctatctcta
     5221 ttatcgaatc gttgcgcacc gactccttca tggagtacgg cgagcccatt gcgcgtatcc
     5281 ttccgtcgga gattatggcc agccggtcgc agagctcgtc cgcctcgaac atgtaatggg
     5341 tggtgagcag tatcgtcatg cccttttccg agagacgcct gatcagcgct cgggtctccc
     5401 gggatatctc cgggtccagt cccaacgtag gctcgtccag gaaaaggacc tcggggtcgt
     5461 ttaccagtcc tcgcgccaaa tgcaagcgct gcttcatgcc tcgggagtat tcctcgaccc
     5521 gaacgtcggc cgcctcggtg agcccgacca gctccagcag gtcctcgatc tttttcttct
     5581 taacatctct cggcacccgg tacatgtcgg agaagaattc caggttctgc ttgccggtga
     5641 gcctgaaata cagaccgcgc tccccgccgg agaccagatt gatgcgcggc cgcagtttga
     5701 ccgggtcctt caccacatcc aggccgagga cggtggcgct gcctgaggta gggataagga
     5761 gtgtggtcag catctttatc gtggtggtct tgccggcgcc gttaggacca agaaggccga
     5821 agatctcgcc acggtgaaca tcgaaggaga cccggtctac ggccagtttc tccttcccac
     5881 cgtcgccgaa gagcctagcc gctgctgggt agaccttgct gaggtcctta acctcgatga
     5941 ccgtctcccg gccgttcatg acgtggcggc aacgttctga cgattataat gagcttacga
     6001 cgtcagcttt ctcagcacgg tctgcagtat cccgccgttg cggtagtaat cgacctccac
     6061 cagggtatcc agccgagcga tggccttgaa ggtcgtggcc ttaccgttct tgtaggcgac
     6121 caccatgacc ggggctctag gccgcatctc gagcagttcg atatcgtact cctcgcttcc
     6181 gtccaatccc agggaagcgg cggtaagacc gggctcgaac tgcaaaggca gaacgcccat
     6241 tcccaccaag ttgctgcggt gtatgcgctc gaaagattcg gcgatcacgg ccttcacgcc
     6301 cagcaggtgc ggtcccttgg ccgcccagtc gcgagagctg ccggtgccgt actccttgcc
     6361 ggccaggacg atgagcggga cgcccctctc cttgtattga tgggcggccg ttgatatgtc
     6421 cgtcaaggtc ccttccggct gcaccttcgt gaacccgccc tcctttccat tggccatgcg
     6481 gttcttcagg cggatgttgg cgaaggtgcc gcgcatcatg acctcgtgat taccgcggcg
     6541 ggaaccgtag gaattgaagt ccttctcccc cacacccaga gagatcaggt actggccggc
     6601 cacgctcccg gccgggaact cgcccgccgg ggagatatga tcggtggtga tgctgtcgcc
     6661 gaggaccagc agggcccggg cgcccttgat gttctgcggc ggtgagaact ccttgctcat
     6721 gccgtcgaag aacggcgcct tgcggatgta ggtggaggtc gggtcccaga tgaacgtctc
     6781 gcccttcggg gcgggcacgg aatcccataa cgcgcttccc tggaacacgg tggagtaggc
     6841 cttgcggtac atggccgggg tgaccttctt cagggcggcc tttacttcct tggccgtcgg
     6901 ccagaggtcc tttaggtaca ccggctggcc gttgggatcg gtgcccaacg gttcggtgtc
     6961 caggtccagg tccaccgttc cggctatggc gtaagccacg accagagggg gcgacgccag
     7021 gtagttcgcc tttacgtacg gggagatacg tccttcgaag ttgcgatttc ccgaaagtac
     7081 cgccgccacg gtgaggtcgt tcttcacgat gtcctcgacc aggtcctccc gggccgggcc
     7141 gctgttgccg atgcaggtga ggcaaccgta tccgaccacg tggaatccca gggcttccag
     7201 gtaggagagc agacctgcct tctgcaggta cgtcgtcacc gccctacttc cgggagccaa
     7261 ggacgtcttc acgttggggt tcggtctcaa tcctctctcc acggccttct tggccaatag
     7321 tccagcggcc atcatgaccg atggattgga ggtattggtg caggaggtga tggaggcgat
     7381 caggacgtcg ccgtccttca tcagattgcc tgtcttcttc ccgccctgct tctccatcat
     7441 cttgccgaac tcggacctca tccgcgatag ttcgatccgg tcctgcggac gcttcggccc
     7501 ggccagggac ggtacgacct tcctcaggtc cagctccatc ctgtcgctgt agtccgggtc
     7561 ttggtcctca tagaacaggc cctgctcccg ggcgtatctc tcgaccagct cgcacagctt
     7621 ctcccgcccg gtcatcttca gataggcgat ggtgacctca tccaccggga agaagcccat
     7681 ggtcgccccg tactccgggg ccatgttggc cagggtcgcg cggtccggaa gcgagaggtt
     7741 ccttattccc gggccataga actccacgaa cttgccgacc acgcccttct tgcgcagcat
     7801 ctccacggcg gtaaggacca tatccgtggc cgttacgccc ggcttgagct tgccagttat
     7861 cttgaagccc accacctgcg gtagcggcat atagtaaggc tggccgagca tgaccgcctc
     7921 cgcctcgatt ccaccgacac cccaccccag tacgcccagt ccattgatct gggtggtgtg
     7981 ggagtccgtt ccgaacacgg aatcggggaa ggccacgccg tcacgggtgg ccaccacggt
     8041 cgccaggcat tccaggttca cctggtgtat gatcccgttt cccggcggga ccacccggaa
     8101 gttgttgaag gagccttgcg cccatttcag gagcgagtac ctttccaggt tccgctccat
     8161 ctccttcctc tcgttgaggt cctgggcgta gcaggtgccg tggtaatcgg tctgcaccga
     8221 gtgatcgatg gtgaggtcca ccgggaccag ggggtttatt cgtgatgggt tcccgcccat
     8281 ttcctttacg gcgtcgcgca tggccgccag gtccaccacg cagggtaccc cggtaaagtc
     8341 ctgcaggacc actcgggcgg gaatgaacgg aatgtccacc tcgtcgttgc cggccggcgt
     8401 ccatccaagt agtttctgga catcctcctt ggtcaccagg atgccatcct cttggcggag
     8461 caaggactcc aggagcacct tgatggagaa cgggaaatgt tcggttcgag catccagctt
     8521 cttcagggaa tagtagctca aaggtccgtc cttcagctcg aggacgctct tggtttggaa
     8581 ggagtccgcc gtcggtgcca tttttctcag atggcagtga gcgaacatgt ccttaaaaca
     8641 ttgcagggga cggggaaaag gatattatga cctcaggggc ttgacctgat tggatgataa
     8701 atccaaccga aggtgtccag gatgattcgg aggagaacta cggcaagcac gccagtgtcc
     8761 tccgctccca gatgaggagg ggtctgatcg gtggcaacac cgaatgcgcc cacttcccct
     8821 gccatcatcc cggacagaac tgcaccttct gcttctgccc tctctatccg tgccttgatc
     8881 cagagctagg ggagtacgtc acgtccaaac ggaccggcgg ccaggtctgg tcgtgccaga
     8941 actgcctttg gatccaccgg gacgatgtct ctagatcgct cttaaagatg atgcctgaga
     9001 tcggagagaa cggtctggac gagagcacca ggtccgagct caaggtcaag ctagaagggg
     9061 tgcatcgcaa gagagccaaa gccatcatgg tgcttggcgc cacgtccggg gctggaaaat
     9121 cgctactggt ggccgcgcta tgccgtgcct tccgggaccg cggcctcctg gtggcccctt
     9181 tcaaatctca gaacatgtcc ctgaactcca tggtgaccgg ggaaggagag gagatcgccc
     9241 gcatccagga cctgcaggcg cgagcggccg gaacacgacc tcgcggggaa cttaacccca
     9301 ttctattgaa acccaagggc ggggtcacct cccaggtcat cgtcgaagga cgcccataca
     9361 aggactgtac ggtgcaggaa tattattcac agttcgttcc gaacgaggcc ccggccatca
     9421 tcgcccgcaa tctggagcgg ctgatgcgtt ccaatgacgt ggtggtcata gagggcgccg
     9481 gctcccccgc cgagatcaat ctgcggggaa aggatgtggc caacatgtac gtggccaagc
     9541 tggccagggc cgattgtctc ctggcggtca acatcgactg gggtggcgcc ttcgcttacg
     9601 caatcggaac gctcatgctg ctggacgatg aggaacgcag gctcttcaag ggcgtcctca
     9661 tcaacaacat gtgtcccggg ggcggctctc tcggggattc tctggaaatg gttaagggaa
     9721 tgaccggagt gccggtgctg gccgtgcttc cgcacgttcc ttctctatac ctcccggtcg
     9781 aggactccat ggacctggat cagcatacgg cggcaggttc cggcacggtc gtggccgtgg
     9841 tccgattgcc gatgatatcc aacttcaccg actttgacgc gctttctctg gaggaaggtg
     9901 tcagggtcat ctacgcccgg acgccggagg atctggaaat ggctgacgcc atcatcgttc
     9961 ccgggaccaa gaacaccgtg caggacctgc tgtggctcaa ggagagcggc atggcgatgg
    10021 ccatcctgtc caagacgaga acggttccta tcctaggcat ctgtggaggc taccagatgc
    10081 tcggccggaa gatattcgac gtccacgggc tggaaggcga tggtccatcg gagatcgatg
    10141 gcctggggct gctggacgcc gtcacccatt tcgattcata cgacaagagg accgtacagg
    10201 tcctgggatg cctggccgat ggcggggagg tgcgcggcta cgagatacac atgggccgca
    10261 ccgaaggcgg cgaggagcca ctgttccgcc tgcagcccga tgggcgggag gaaggatgct
    10321 ggaaccggga acggaaggcc atgggtacgt acatgcacgg ggtattcgac ctgccggcgt
    10381 tccgtcgctt cttcctatcg atgatcgagc gccgagatgc cgaaggaact aatggaatgg
    10441 accacgacgc cgagatcgat tcctctttgg acagattggc ggcgatgatc gaggaacatc
    10501 tagacctcga tgagctgctc ggaggtgatg tccatggtcc gtaggctgat ggtccagggt
    10561 gtgacgtccg gggctggcaa gacgacgctg accgccgcgt tatgccggca cttctccacc
    10621 cgtgggacgg acgtcgtccc tttcaaggcg cagaacgtat cgctcaactc ctacgttacc
    10681 agggacggca aggagatggc catttcgcag gcttaccagg cctgggcctg cgggttggag
    10741 ccctcggcgg agatgaaccc cattctgatc aagccgaagg gcaacgggca atgccagata
    10801 gtccttcgcg gcaagccatg gaaggacctg ggaccgagag ggagcacgcc cgaggtcatc
    10861 gatatgctga gggagcaagt gatggcggcg ttcaacgaca acgcctcagg aagggagctg
    10921 gtgctgatcg agggcatggg gtctccggtc gaaatgaacc tcaaggacaa ggatgtcagc
    10981 aacatgtggc tggccaaggc cacccgttca ccggtgattc tagtggggga catagagaag
    11041 ggtggcgtgt tcgccggact gtacggcacc tatcttctcc tggatgggga ggagagggac
    11101 cttctgaaag gtttcgtcat caaccgcttc cggggcgacg cctcaattct taaggaaggg
    11161 atcgaggaac tggagtcccg aatggagatg ccctgcctag gcgttctgcc gatggtccgg
    11221 ttccgcgccc cggccgagga ttccatggat ctgaccagag cctccgggaa cggtgtcggc
    11281 tcgggggacg tcaggcaact ctggatgaaa gaactggacg gggtcttgga aaaatgggaa
    11341 ggggcctggg accttggaca ggtccgaagg cttatcgatt aggtctgcgg tctcaaaggc
    11401 gattgccgca cttctggcag aactgggcgc caggctctat tctggctccg cagctacggc
    11461 aattgtagat ctgctgcggg ggttgctgat atggctgctg atacggttgt tgatatggtg
    11521 gactcgggtt gccgtaatag cccgttccat actgcgggcg ctcctcatac ttcatgaaga
    11581 aatagataag tgccgcaggc cagcaaatga ttaacaggat gatgaggatg gcccaactgc
    11641 cagtaaaatc ctttgacatt acattccacc ttttagtgta aatccctcga ggaaatattt
    11701 attcattccc ctttatttac tgtgatgcag gttcaccgac cgcgcgcatt gtggatagga
    11761 ggcacggtcc ggacattcct tgcaacgctt gcgcatcttt ctgcccttca agaactcgaa
    11821 ggtaatgatc acaccgatta tgaagggata gaccaagatc ctgaggtcga gtgggcaaac
    11881 gatgatggaa tacacggtca ttgccaggct tgatcctagg acagtattga aaaaaatgga
    11941 tattctcctc cccgtggtga tgaatcgaga cagttgagcg cagaacagta aaagcgatcc
    12001 aacgaaggcg accatgaaat ccggtcgaac cataagtagg atgatcaaca tgaccgcgaa
    12061 ggtcggatag accgtgatac agccccggca gacctttcta cctcggatgg taagcaggtg
    12121 atcgctgaat cgaccgcaga ggggatggtg ggaaagcagg atgggttcgt tcctcagctc
    12181 gtacatgaac ttgatgtcct cacctcctcc tatgacacca ccatactggt gtgccattga
    12241 taaaaaataa ccgacaactg atttatactt ggatgatata tccaattgag ttggattata
    12301 catccaacta actaattgaa agtgattcca catggataag aaggcaataa tcgcaatcat
    12361 actggtcgtg gccctggtgg ccgtcgggac cataatggta ttgggaatga acccctccgg
    12421 tggcgaggat gatggaccgg tcaaggtcat tgacgccagc ggaaggcccg tgaccaccaa
    12481 cgagacgccg atgcgcatcg tctcctgctc cccatccctc accgagatgg tctatgccat
    12541 gggcataggc agccacctgg tggcggtcac cgattactgt gactggccgg ccgatgtcaa
    12601 cgt
//
LOCUS       DAOPZI010000038        12514 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_5628_length_12514_cov_9.066619, whole genome shotgun sequence.
ACCESSION   DAOPZI010000038 DAOPZI010000000
VERSION     DAOPZI010000038.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 12514)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12514)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12514
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5628_length_12514_cov_9.066619"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..789
                     /locus_tag="PKM11_07080"
     CDS             <1..789
                     /locus_tag="PKM11_07080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48302.1"
                     /translation="DPVLKAEVGKPILIKVNVTDRVGIGSVVLEYTIGNVTRTVVMTH
                     EGGGIYFAQIPAQKRTMELRYRIIANDTTGHSASTDEFTLVLEYEDPSLFIYSSLALL
                     IAFLVIIIYLFLSRPIVDEVFVMYHDGTLLAHQTRRLKPGMDDEILGGMLIALQNFVR
                     DSFKDENITVLRRMDFGDRKLLVERKDDFFIAVVLSGKRAGNAAQRMLKVLDNIDENY
                     APVLREWDGDLEKVRGIREETKPMFSRANPLDRLKRKEGEDDSI"
     gene            817..1536
                     /locus_tag="PKM11_07085"
     CDS             817..1536
                     /locus_tag="PKM11_07085"
                     /inference="COORDINATES: protein motif:HMM:NF014049.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF92 domain-containing protein"
                     /protein_id="HNX48303.1"
                     /translation="MITIEQAVIVLVLCAALCALSWKLGLLTADGSLASFAVGMVLGL
                     FGGIGWLLLLVLFAFIGFAVTRYKMDLKIKRGVQEGKKGERGYRNVLANGAVPMAVAI
                     LSFLLGWEGELPALIYMSAVCVAAADTTASELGVLSDRTYMITTLKRVPTGVDGGVSL
                     YGTGWAIAASAFAALVGWLVILGTVPSLLILVPVSMGILGCFIDSVIGATLETKGWVT
                     KLWNNISSMALGAVVALLVLL"
     gene            1593..1713
                     /gene="rrf"
                     /locus_tag="PKM11_07090"
     rRNA            1593..1713
                     /gene="rrf"
                     /locus_tag="PKM11_07090"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(1796..10741)
                     /locus_tag="PKM11_07095"
     CDS             complement(1796..10741)
                     /locus_tag="PKM11_07095"
                     /inference="COORDINATES: protein motif:HMM:NF028519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdrD B-like domain-containing protein"
                     /protein_id="HNX48304.1"
                     /translation="MISAGFVTLLQFAADTGSGESYPAEHFVGFDLESGTWVNSDLGK
                     AYMEGDFVSYQLRLDSSSKIWGAEEFSIKYNFYQGSTNAIFVDGFDTSVGSGFQYSTG
                     DMLADGVQVPSSGWGTHIPTPEAGETAAFGDPQIVNYMNVWEVGDPDSEAAPNDMRYF
                     TIKNIPWEDFTDGHVILFFRAHLALSIIWRNDLEVALPQALDGNEFQGWTGASPHFGS
                     SYASGSSRHFTIEYPGVGGKAIPIPITSYPTNLITGRKLINNVPYDGWVMNLEGRLSL
                     WGGTGDDYVYIPFNPPAVVTGNGPWALGYFAFDGLPRGNFTVWEDHKEGFILDVIGTS
                     PYLNLYAPGKLPYFDAVTESWMDNPDANERVRFDLDRGTKVSPKVQNIDFYNLQVGNL
                     SGYKVHDINGDGSIDDGDTGLAGWSIELWEEDGLSPVRVTTTDDDGYFEFKDVVIGNY
                     SVKEVMQDGWFNTTSDSISVRVDPGSDIDDLLFLNTMYSSICGYKVQDIDGDGVWDEN
                     DPVIYNWEIQLFKGDKLIDTTWTDESGRFCFDGIVPGHYTVTEVLPSNWYCTDEISYA
                     FDIESGDHEDVVFLNSNMVSISGYKYEDLMGDGVYDDGEDLGISGWTIYLYEGAIEPD
                     EAPIRSNVTDANGRFSFTGLEVGTYTVVEESRLGWYNTTPGQIEVTLLSGESEELMFL
                     NTEYAEICGYKYEDMNGDGRLDDGDPAVQGWEVELWFDGVYQETTFTDECGRFCFDMI
                     TPGTYVVKEVMQEDWYATTPEEVEISKVSGGDDGTVTFLNTRYGDICVFKYEDLDGDG
                     EWDEGEPGMPGVTVELFEPIMERALSSEPTPIRTGVTNETGMVCFHGLFLGTYLVVEY
                     PPLGTYPNTEGTSKLVEITTSNQSVPVTFGNIENGKICVLKYEDIDGDGVLDEDETTP
                     LSGVLVTLYDAQMVEIANGITGECPCGCGGICFSGLALGTYFVRETVADGWFNTTPAQ
                     VQVVLDVSGETEQVFFLNSEYSSISGNKYQDLDGDGFLDLDDMPVENWEIQLWRDDVY
                     VATNWTDDEGYFFFGDLVPGNYYVIEIMQEGWYATTTTEVYVRIDSGVHVGDVLFLNT
                     IYSSVCVFKYEDLNGDGQWTDDEPAIPDWEFKLYRMADEVPTFVQMVGGWVLVATNST
                     DDSGRSCFTGLVPGLYKIEEVMQDGWYNTTEASHVFEITSGDRESFTFLNTEMGRICG
                     YKVEDLNGNGQRDEDEVGVEGWHIELWKDGEFYSETWTAADGSFCFANLSPGDYVVYE
                     GENSSWYNTSADFAEREISSGTVVDDIVFLNTRYGQVCVLKYEDENGNGVRDEGEDVL
                     VDGVFIELLLGQTVVRSGYTGESEGGAICFTGLKLGDYVVRETLNEGWYTEGPLEQSA
                     VIDLSGESIELTFVNIRLGQICVLKYHDLDGDGLRDGNEPVKAGVTIELLYPNGTLIE
                     SAVTDESGMVCFTGLVLGDYVVNETVPEGWYATNGTSFEVSVETSGQYIEVEFLNTEF
                     GRICVYKYEDLNGNGVLDEDEPAVSGVFIELLRDGKVIANGTTDDDGRICFTGLYLDE
                     YLVRETVPEGWYNTNPTEVSVTIDQSGEGQEATFLNTRYGQICVFKYEDLNGNGVNDD
                     EPVVEGVFIELMLDGEVVASGCTDCYGMICFTGLKLGDYTVNETVQEGWYATSPTSVG
                     VSLAASGDHRSVEFLNARYGSICVYKYEDLDGDGEWDEGEDHLIDGVAIVLRNVTGEI
                     VDTGVTGDNGDGTVCFTNLVIGVYTVEETVPQGWYATSGTTRSVGLEASGDQNCTYFL
                     NTMYGRICVFKFEDLNGDGEWQENEPAVSNVTIELRDLAGGLIETNVTDCEGIACFCG
                     LMLGSYVVIELVPEGWYADETNQFAVLEQSGETVWVEFSNLKYSKICVQKIEDENGNG
                     IRDEGEETPISGVFIELLLDGDVIASGYTDCYGMICFTDLVIGEYTVRETVPEGWYNT
                     TLAEVVEVIEGSGQSKCVTFLNTEYGDICVQKYEDVNGNGEMDEGDRPASGVIINLWL
                     GDGIIATNETDRDGIACFHMLRLGAYKVQEVLPEGWYTDGLLIQGAVIEGSGDHVQVT
                     FLNIRYGEICVWKYEDVNGNGLLDDGDAVVPGILITLYDAQMNEIANGTTGECGGICF
                     SGLVLGTYFVGETLTDEWYTEGPTLKQVSVNESGDVVCEHFLNIRYGKICVFKFEDLN
                     GDGVWQENEPGLSGVVIQLVQDCKVVRTGVTNATGWVCFELLRFGSYIVRENLALSDM
                     GCCWYPSTPDRVSVTLSVENQHQLVIFGNVKYGKICGWKYLDENQNGRFDECTEHGIA
                     GWTIQLWKDGVLFGTMTTDSRGHFCFAGLEFGEYVVTEVMQDGWYATGQISWNVTIDR
                     SGDREDVFFLNAPCGDICVYKYEDLDGDGVLDEGEPAVPGITVYLYQDNVLVGSGVTD
                     ENGRYCFEDLKVGTYAVMEEIPCNWYATAGRVQQAVMTGQDVTVTFLNTRYGCIGGFK
                     FNDANGNGVWDMLTESGIAGWEIELYQGEQLISWSLTDADGHYAFCGLRLGDYTVKEV
                     MQDGWMATAPTEIMVTLETSGQLVCNQNFLNKELNPCIDVDKSVVCDTITWESHTQGY
                     WKNHECSWVGIRPYDRFPWVNRCAYPCGLTYLGVFGQPPAGDATLILAHQYIAAKLNY
                     LKWGAPVMYNDLIAEAEAFLAMHPIGSCLTKGEKAEATELADLLTAYNEGEGGLTVLT
                     YTVTVTNCGNVELYNVKLYDSLLEQWFYLCDFGDGDGILGIGEWWTISYTYVVPVDIC
                     EESEDTCGGWTWEWEHGCGGGCHYGDNDNDCWSWSWGCGDRDGRHDGGCGGWNWNRGY
                     GTGCGAWTWCWSHHCGGGCDEEPAESCVITNIATAYGQWGAESAGTWVSDSDQVNFRV
                     QQECPNGDDDDGCGYHDWNWNWGGGCGDHDWGCDHDGGWSWSGCGWIYQNLNFGGCRW
                     WGLFSDGMIGACHVWNGYGTRDDARGKEETEAVEEEK"
     gene            11221..11341
                     /gene="rrf"
                     /locus_tag="PKM11_07100"
     rRNA            11221..11341
                     /gene="rrf"
                     /locus_tag="PKM11_07100"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            11463..12245
                     /locus_tag="PKM11_07105"
     CDS             11463..12245
                     /locus_tag="PKM11_07105"
                     /inference="COORDINATES: protein motif:HMM:NF024183.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HNX48305.1"
                     /translation="MFLIILLIVLGAVIYFELRFMRSRNKDYVKQVLEKDEVHNAITT
                     TQAIASSLRQRGRDTKEAENILSLAESAYIRKDLSAAKGLAMKARDILVSLPVVAIAP
                     IAQEAPVEQPDPERKTVQEVKKLEPHMLESRFIINSCRDRLRSCSESGMDVKEAEGHL
                     TMAERSFEEKKYDEALKEGMKARRLLCESSSDTAEPVKDAVIVKIPKPETKCEKCSAT
                     VNSDDLFCRKCGAPIIMKRSCAHCQAEMGDGDVFCPKCGRRA"
     gene            12298..>12514
                     /locus_tag="PKM11_07110"
     CDS             12298..>12514
                     /locus_tag="PKM11_07110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HNX48306.1"
                     /translation="MILVKLGGSVITDKGRYRTFDPETTDRLAEEIARTGQDVMVVHG
                     AGSFGHMLAKEHRLHLGLTEDSQLLGAS"
BASE COUNT         2500 a         3824 c         3480 g         2710 t
ORIGIN      
        1 gacccggtac tgaaggccga ggtcgggaaa cccatactga tcaaggtgaa cgtgaccgac
       61 cgagtaggca ttgggtcggt ggtgctggag tacaccatcg gaaatgtcac caggaccgtg
      121 gtcatgaccc atgagggtgg cgggatatac ttcgcccaga tacccgcgca gaagcgcacg
      181 atggaactga gataccgcat catcgccaac gacacgaccg gtcattccgc ctccacggat
      241 gagttcaccc tggtcctaga gtatgaggac ccctcgctgt tcatctattc gtccctggcg
      301 ctgctgatcg ccttcctggt catcatcatc tatctgttcc tctcccggcc gatcgtggac
      361 gaggtgttcg tcatgtatca cgacgggacg ctgttggcgc atcagaccag acgattgaaa
      421 ccgggcatgg acgacgagat acttggcgga atgctgatcg ccctgcagaa cttcgttcgt
      481 gactcgttca aggacgagaa cattaccgta ctgaggagaa tggacttcgg tgatcgcaag
      541 ctgcttgtgg agcgcaagga cgacttcttc attgcagtgg tcctcagcgg caagcgcgcc
      601 gggaacgccg cgcagcgcat gctcaaggtc ctcgataata tcgacgagaa ctacgccccg
      661 gtgctcaggg aatgggacgg ggacctggag aaggtgcgtg ggataagaga ggagaccaag
      721 cccatgttct cgcgcgccaa ccccctggac aggctgaaac gaaaggaagg ggaagacgat
      781 tccatttaaa tattttagaa ttctagggag gaaagaatga tcaccataga gcaggcggtc
      841 atagtgctcg tgctgtgcgc ggcgctttgc gcgctatcgt ggaagctcgg actgctcacc
      901 gccgacggta gcttggcctc cttcgccgtg ggcatggtgc tcggactttt cggggggatc
      961 ggatggcttt tgctactggt gctcttcgcc ttcatcggct tcgcggtcac caggtacaag
     1021 atggacctga agatcaagag aggggtgcag gaaggaaaga aaggcgagcg gggctatcgc
     1081 aacgtactgg cgaacggcgc ggtcccgatg gccgtggcga tccttagttt cctgttgggc
     1141 tgggaagggg aactgcccgc cctcatctac atgagcgccg tatgcgtggc cgcggcggac
     1201 actacagcca gcgagcttgg tgtcctttcc gaccgcacct acatgataac caccttgaaa
     1261 cgcgttccga cgggagtgga cggcggtgtt tccttgtacg gaacgggatg ggccatcgcc
     1321 gcctcggcct tcgccgccct ggtgggatgg ttggtaatat taggaacggt tccttcgctc
     1381 ctgatcctgg tcccggtgtc catgggcatc ctgggatgct tcatcgacag cgtcatcggc
     1441 gccacgctgg agaccaaggg ttgggtcacc aaactatgga acaacatatc gtccatggcc
     1501 ctgggcgcgg tggtcgccct gctggtactc ctctgaacga ggactgagaa acagttatat
     1561 acgatgttct tttaactggg tcctaaggat ggtttgacgg ccatcgcggc ggggatacgc
     1621 ctggtctcgt ccgatcccag aagctaagcc cgcccgcgtt cactgtggta ctgtggtgcg
     1681 cgagcccacg ggaagctccg aacgctgtca gcctccttac tttttcattt tatccaaaat
     1741 agggactttt taaaaaaaag aaatgtcagg gggtcgcccc ccttgttgag gtcgttcact
     1801 tttcttcttc gacagcttcg gtctcctcct tgccccgggc gtcgtcccgg gtgccgtaac
     1861 cgttccagac gtggcaggcg cctatcatac cgtcgctgaa cagcccccac caccggcaac
     1921 cgccgaagtt caggttctgg tagatccatc cgcagccgct ccaagaccag ccgccatcgt
     1981 ggtcgcagcc ccagtcgtgg tcaccgcagc cgccgcccca gttccagttc caatcgtggt
     2041 aaccgcagcc gtcgtcgtca tccccgttgg ggcattcctg ctgcaccctg aagttcacct
     2101 ggtcactgtc gctgacccat gtgccggcgc tctctgcccc ccattgcccg taggcggtgg
     2161 cgatgttggt tatgacgcag gactcggcag gctcttcatc gcaacctccg ccgcaatggt
     2221 gactccagca ccacgtccag gcgccgcatc cggtgccgta tccgcggttc cagttccagc
     2281 cgccgcagcc gccgtcatgg cggccgtcgc gatcgccgca accccatgac cagctccagc
     2341 agtcgttgtc attgtcgcca tagtgacagc caccgccgca gccatgctcc cattcccagg
     2401 tccagccgcc gcaggtatcc tcactctcct cacagatgtc caccgggacc acgtaggtgt
     2461 aggatatggt ccaccactcg ccgataccca atattccgtc gccgtccccg aagtcacaga
     2521 ggtagaacca ctgctcgagc agggagtcgt atagtttgac gttgtatagc tccacgttcc
     2581 cgcagttggt gacggtcacg gtgtaggtga gcaccgtcag accgccctcg ccctcgttgt
     2641 aggcggttag gagatcagca agttcggtgg cctccgcctt ctcgcccttg gtcaggcaac
     2701 tgcctatggg atgcattgcc aggaaggcct cggcctcagc gattaggtcg ttgtacatga
     2761 ccggcgcgcc ccacttgagg tagttcagct tggccgctat gtattggtgc gccaggatca
     2821 aagtggcgtc gcccgccggg ggctgcccga acacgccgag gtaggtcagt ccgcaagggt
     2881 aggcgcatct gttgacccag gggaaccggt cgtagggcct gatccccacc caggaacatt
     2941 catggttctt ccagtagccc tgggtgtggg actcccaggt aatggtgtcg cagaccacgc
     3001 tcttatccac gtcgatgcag gggttcagct ccttgttgag gaagttctgg ttgcacacca
     3061 gttgcccgga ggtctcgagg gtcaccatga tctccgtggg agcggtggcc atccagccgt
     3121 cctgcatgac ctctttgacc gtgtagtcgc cgaggcgcag gccgcagaag gcatagtgcc
     3181 cgtcggcgtc cgtcaaggac caggagatga gctgttcgcc ctggtagagc tcgatctccc
     3241 aaccggctat tccgctctcg gtgagcatgt cccagacacc gttaccgttg gcatcgttga
     3301 acttgaagcc cccgatgcat ccgtacctgg tgttcaggaa ggtcaccgtg acgtcctgtc
     3361 cggtcatgac cgcctgctgc acccggcccg ccgtggcgta ccagttgcag gggatctcct
     3421 ccatgaccgc gtaggtgccg accttcaggt cctcgaagca gtaccggccg ttctcgtccg
     3481 tgacgccact gcccaccaac acgttgtcct ggtagaggta gaccgttatg ccaggcacag
     3541 cgggctctcc ctcgtccagg acaccgtccc cgtccaggtc ctcgtactta tagacacata
     3601 tgtcgccgca cggggcgttc aggaagaaca catcctcccg gtcgccggag cggtcgatgg
     3661 tcacgttcca agatatctgc ccggtggcgt accagccgtc ctgcatgacc tcggtgacca
     3721 cgtattctcc gaactccagt cctgcgaagc agaagtgccc gcggctgtcg gtggtcatgg
     3781 tgccgaagag tacgccatcc ttccacagct gaatggtcca gccggcgatg ccgtgctcgg
     3841 tgcactcgtc aaagcgtccg ttctggttct cgtcgaggta cttccaaccg catatcttgc
     3901 cgtacttgac gttaccgaag atcaccagct ggtgctggtt ctccactgac agcgtcacgc
     3961 tcacccggtc aggggtggac gggtaccagc agcagcccat atcgctgagg gccaggttct
     4021 cccggacgat gtacgaaccg aagcgcagta gctcgaagca tacccaaccg gtggcattgg
     4081 tcacgccggt cctgaccacc ttgcagtcct ggaccagctg gatcaccacc cccgacaggc
     4141 cgggctcgtt ctcctgccac acgccgtcac cgttaaggtc ctcgaacttg aagacgcata
     4201 tctttccgta gcgtatgttc aggaaatgct cgcagaccac atctccggat tcgttgacgg
     4261 acacctgctt gagcgttggg ccttcggtgt accattcatc ggtgagcgtc tcgccgacga
     4321 agtaagtacc aagcaccagt ccgctgaagc atatgccacc gcactcaccg gtggtgccgt
     4381 tggcgatctc gttcatctgc gcgtcgtaaa gggtgatgag gatgcccggt accacggcgt
     4441 cgccgtcgtc cagcaggccg tttccgttga cgtcctcata cttccagacg cagatctcgc
     4501 cgtagcgtat gttcaggaag gtcacttgga cgtggtcccc ggacccttcg atcaccgcgc
     4561 cctggatcag cagtccgtca gtgtaccatc cctccggcag gacctcctgc accttgtagg
     4621 cgcccagcct cagcatgtgg aagcaggcga tgccgtcgcg gtcggtctcg ttggtggcaa
     4681 tgatgccgtc gccaagccag aggttgataa tgaccccgga cgccggcctg tcaccctcgt
     4741 ccatctcacc gttgccgttg acatcctcgt acttctgcac gcagatgtcg ccgtactcgg
     4801 tgttcaggaa ggtcacgcac ttggactgtc cggaaccttc gatgacctca acgacctcgg
     4861 ccagggtggt gttgtaccat ccctcgggga ccgtctcccg caccgtgtat tcgccgatca
     4921 ccagatcggt gaagcagatc atgccgtagc aatcggtgta tccggaggcg atgacgtcac
     4981 cgtcgagcag cagctcgatg aacacgccgc ttatcggggt ttcctcgccc tcgtcccgta
     5041 tgccgttgcc gttctcatcc tctatcttct gtacgcatat cttggagtac ttcaggttcg
     5101 agaactccac ccagacggtc tctccggact gctccagtac ggcgaactga ttggtctcgt
     5161 cggcgtacca gccttcaggc accagctcga tcaccacgta ggagccaagc atcaggccgc
     5221 agaagcaggc gatgccttcg cagtcggtca cgttcgtctc gatgagcccg ccggccaagt
     5281 ccctcagttc gatggtcacg ttggacactg ccggttcgtt ctcctgccac tcgccatcgc
     5341 cgttcaggtc ctcgaacttg aagacgcaga tccgaccgta catcgtgttg aggaagtacg
     5401 tgcagttctg gtcgcccgat gcctctaggc ctaccgagcg ggtggtgccg ctggtggcgt
     5461 accagccctg cggcactgtc tcctcgaccg tgtatacgcc gatgaccagg ttcgtgaagc
     5521 acaccgttcc gtcgccgttg tcgccggtaa caccggtgtc cacgatctcg ccggtaacgt
     5581 tcctcaggac gatggccacg ccgtcgatca ggtggtcctc gccctcatcc cactccccgt
     5641 cgccgtccag gtcctcgtac ttgtacacgc agatggagcc gtagcgggcg ttgaggaact
     5701 ccacggacct gtgatcgccg ctagcggcga gggacacacc gaccgaggtc ggggaggtgg
     5761 cataccaacc ttcctggacc gtctcgttca ctgtgtaatc accgagcttc agtccggtga
     5821 agcagatcat gccgtagcaa tcggtgcatc cggaggctac gacctccccg tcaagcataa
     5881 gctcgatgaa cacgccttcc acgaccggct cgtcatcgtt cacaccgttg ccgttcaggt
     5941 cctcgtactt gaatacgcag atctgcccgt acctggtgtt caggaaggta gcctcttgcc
     6001 cttctccaga ctggtcgatg gtgacgctaa cctcggtcgg gttggtgtta taccatcctt
     6061 caggaaccgt ctccctgacc aggtattcgt ccaggtacag cccggtgaag catatccttc
     6121 catcatcatc ggtcgttccg ttggcgatga ccttaccgtc gcgcagcagc tcgatgaaca
     6181 cgccagacac cgccggttca tcttcgtcca ggacaccgtt cccgttgagg tcctcatact
     6241 tgtaaacgca tatgcgtccg aactcggtgt tgaggaactc cacctcgatg tactgcccgg
     6301 aggtttccac ggacacctcg aagctggtgc cgttggtggc gtaccatcct tcgggcacgg
     6361 tctcgttgac gacgtaatca ccaagcacca ggccggtgaa gcagaccata ccgctctcgt
     6421 ccgtgaccgc gctctcgatc agcgttccat tggggtagag cagctcgatg gtcactccgg
     6481 ccttcaccgg ttcgttgcca tcgcgcaggc cgtccccgtc gagatcatgg tacttgagca
     6541 cacatatctg gcccaggcga atgttcacga aggtcagctc gatggactcc ccggacagat
     6601 cgatcaccgc ggactgctcc agcggcccct cggtgtacca tccttcgttc agggtctccc
     6661 tgaccacgta gtcgcccagt ttcagaccgg tgaagcagat cgctccgccc tcagactcac
     6721 cagtgtagcc ggagcgtacc acggtctgac cgagtagcag ttcgatgaac accccgtcca
     6781 ccaggacatc ctcgccctcg tcccgtacac cattgccgtt ctcatcctcg tacttgagga
     6841 cgcagacctg cccgtatctg gtgttgagga agacgatgtc atcaacaacg gtaccggagg
     6901 atatctccct ctccgcgaag tccgcggagg tgttgtacca gctgctgttc tcgccttcgt
     6961 acaccacata gtcaccgggc gataggttgg cgaagcagaa gcttccgtca gcagcggtcc
     7021 aggtttcgga gtagaactcc ccatccttcc acagctcaat gtgccatcct tccacgccaa
     7081 cctcatcttc gtcccgttgg ccgtttccat tgaggtcctc caccttgtag ccgcagatgc
     7141 ggcccatctc ggtgttgagg aaggtgaagc tctcccggtc gccggaggtt atctcgaata
     7201 catggctcgc ctcggtggtg ttgtaccagc catcctgcat gacctcctcg atcttgtaca
     7261 gtccaggcac caggccggtg aagcaggacc tcccgctatc gtcggtactg ttggtcgcta
     7321 ccagcaccca gcctccgacc atctgtacaa aggtcggaac ctcgtccgcc atgcggtaga
     7381 gcttgaactc ccaatcgggt atggccggct catcgtccgt ccattggcca tctccgttca
     7441 ggtcctcgta cttgaatacg cagaccgagg agtatatggt gttcaggaac aggacgtcgc
     7501 ccacatgcac cccggagtcg atgcgaacgt agacctcggt ggtcgtggtg gcgtaccagc
     7561 cctcctgcat gatctctatg acatagtagt tcccgggaac taggtcgccg aagaagaagt
     7621 atccctcatc gtcggtccag ttggtggcta catacacatc gtcccgccaa agctggattt
     7681 cccagttctc caccggcatg tcatcgaggt ccaggaagcc gtcgccgtcc aggtcctgat
     7741 acttgttgcc gcttatcgag gaatattcgg agttcaggaa gaacacctgt tcggtctccc
     7801 ctgaaacgtc caggaccacc tggacctgag ccggggtggt gttgaaccaa ccatcggcca
     7861 cggtctccct gacgaagtag gtgcccaggg ccagcccgct gaagcatatg cctccgcagc
     7921 cgcacgggca ttctccggtg atgccgttgg cgatctccac catctgagcg tcgtacagag
     7981 ttaccagcac cccgctcagc ggggtggtct cgtcctcgtc aaggactccg tccccgtcga
     8041 tgtcctcgta cttgagaacg catatcttcc cgttctcgat gttaccgaag gtcaccggga
     8101 cggactggtt ggaggtggtt atctccacca gcttggacgt cccttccgtg ttgggatagg
     8161 tgcctagcgg aggatactcc acgaccaggt aggtccctag gaacagaccg tggaagcaga
     8221 ccattccggt ctcattggtc accccggtcc tgatcggtgt tggttcggac gacagggccc
     8281 gttccatgat cggctcgaaa agctccaccg tcactccggg catgcccggc tcgccctcat
     8341 cccactcccc gtcgccgtcc aggtcctcgt acttgaagac gcagatgtcg ccgtagcggg
     8401 tattgaggaa ggtgaccgtg ccatcatctc cgcccgagac cttgctgatc tccacttcct
     8461 caggggtcgt ggcgtaccag tcttcctgca tgacctcctt caccacatag gtccctgggg
     8521 ttatcatgtc gaagcagaag cgcccgcact cgtcggtgaa ggtcgtttcc tgatagaccc
     8581 cgtcgaacca cagctcgacc tcccagcctt gcacggccgg atcgccgtca tcgagccggc
     8641 cgtcgccgtt catgtcctcg tacttgtaac cgcatatctc agcatactcg gtgttgagga
     8701 acatcagctc ttcggactca ccggatagca gggtcacctc tatctggcct ggagtggtgt
     8761 tgtaccagcc cagacgactc tcctccacca ccgtgtaggt tccaacctcc agaccggtga
     8821 aggagaagcg gccgttcgcg tcagtgacgt tgctgcgtat gggcgcctcg tcaggctcga
     8881 tcgcaccttc gtacagatag atggtccagc ccgagatccc gaggtcctcg ccatcgtcgt
     8941 aaacgccgtc gcccatcagg tcctcgtact tgtagccact gatggacacc atattgctgt
     9001 tgaggaagac cacgtcctcg tggtcacccg attcgatgtc aaaggcgtaa gatatttcat
     9061 cggtgcagta ccagttcgat ggcagaacct ctgtcaccgt gtaatgccca ggcactatac
     9121 cgtcgaagca gaaccttccg ctctcgtccg tccaggtggt atcgatgagc ttatcgccct
     9181 tgaacagctg gatctcccag ttatagatga ccgggtcgtt ttcgtcccag accccgtccc
     9241 catcgatgtc ctgaaccttg tatccgcata tggacgagta catggtgttg aggaagagca
     9301 gatcatcgat atctgaaccg ggatcgacgc gcacgctaat cgaatcggag gtggtgttga
     9361 accatccgtc ctgcatgacc tccttgacgg agtagttccc gatgacgaca tccttgaact
     9421 cgaagtatcc atcgtcgtcg gtggtggtca ccctcaccgg ggacaggccg tcctcctccc
     9481 atagctcgat gctccatccg gccagtccgg tatctccatc atcgatgctg ccgtccccat
     9541 tgatatcatg caccttgtaa ccggataggt tgcctacctg caagttgtag aagtcgatgt
     9601 tctgcacctt gggggatacc ttggtgccgc gatcgagatc gaaacggacc ctttcattcg
     9661 catcgggatt gtccatccat gactcggtca ccgcatcgaa gtaaggcaat ttaccgggcg
     9721 catagagatt gaggtacgga ctggtgccta tgacgtccag aatgaaacct tccttatggt
     9781 cttcccaaac agtgaaattg ccgcggggga gaccatcgaa ggcgaaataa cctagggccc
     9841 aaggcccgtt cccggtcacc accgccgggg gattgaaagg tatgtagacg taatcatcgc
     9901 cggttccccc ccagaggctc agccggcctt cgaggttcat gacccatcca tcataaggaa
     9961 cgttgttgat cagcttgcgc ccggttatga ggttggtggg ataggaggtg atggggatgg
    10021 gtatggcctt gccgcccact cccggatact caatggtgaa atgacgtgag gaaccgctgg
    10081 cgtaggagga gccgaaatga gggctcgccc cggtccatcc ttggaactcg ttcccatcta
    10141 gggcttgggg aagggcgacc tccaggtcat ttctccagat gatcgaaagg gccaggtggg
    10201 ccctgaagaa caatatgaca tgaccatccg tgaagtcctc ccacggaatg ttcttgatcg
    10261 tgaagtaacg catatcgttg ggggcagcct cgctatctgg atcgccgacc tcccatacgt
    10321 tcatgtagtt aacgatctgc ggatcgccaa atgccgcggt ctcgccggcc tcaggggtcg
    10381 gtatgtgcgt gccccagccg gaggaaggga cctgtacgcc atccgccaac atgtcgcccg
    10441 tggaatattg gaaaccagaa cctacggacg tatcgaaacc atcgacgaat atggcattgg
    10501 tggatccctg atagaagttg tacttgatgc tgaactcctc ggcgccccag atcttgctgg
    10561 agctgtccaa tctaagttga taggagacga agtccccttc catataggcc tttcccaggt
    10621 cgctattgac ccaggtgcca ctttccaggt caaagcctac gaagtgttca gccggatatg
    10681 attccccgga ccccgtgtcc gccgcgaact gcagcagggt tacgaacccc gcgcttatca
    10741 tcagaaccgc aattaagatt gaagctatct tcttaatgtc gatacctttg tcttcatcgt
    10801 tactggcact catgccctgt tcccccccta cttgacccaa tcctgacaga tggtgccatt
    10861 tgtgcggatg tagttttatt agtagagagt aaatcgtctg tcgggcgatc gagtcgtatg
    10921 tgaactacta gtgggtgcgt atataagcat tattatcatc gatgataaca ccgtattgat
    10981 gattcagatc ggacccggaa ggccagtcca gcatagatta atatttttat aacaatttaa
    11041 caatatttga attgaggcgg ccctgatatc tccgatgatg aggaccgatt aacccatgtt
    11101 aaatattata ggaacatagt aactctttta gacccgagaa aattcacgcc taacgtgcat
    11161 cgacatccgc catctgaaca aaatataaat aatcgaatgg agtgcactgg ttcagaatgg
    11221 tttgacggcc atcgcggcgg ggatacgcct ggtctcgtcc gatcccagaa gctaagcccg
    11281 cccgcgttca ctgtggtact gtggtgcgcg agcccacggg aagctccgaa cgctgtcagc
    11341 cattctatta ctttcttctc ttcttgctcg gcctggaagc ttcattcgaa ccatagaatt
    11401 attattcatc aagaacctaa tgcttgattg ggccgaaggt gttatagctg gattcgaacc
    11461 aggtgtttct gatcatactc ctcatcgtgc ttggagcggt catctatttc gaactacgct
    11521 tcatgcggtc gcgcaacaag gactacgtaa aacaggtgct ggagaaggac gaggtccaca
    11581 acgccataac caccacccag gccatcgcct cctcccttag gcaaaggggg agggacacca
    11641 aggaggccga gaacatccta tccttggccg agagcgccta tatccggaag gacctctccg
    11701 ccgcgaaggg attggcgatg aaggcccggg acatcttggt cagcttgccg gtagtggcca
    11761 tcgcgccgat agcccaggaa gccccggtgg aacagccaga tccggagagg aagaccgtcc
    11821 aggaggtcaa gaaacttgaa ccgcatatgc tggaatcccg cttcatcatc aactcctgtc
    11881 gcgaccggtt acggtcgtgt tccgaatccg ggatggacgt gaaggaggcc gagggtcatc
    11941 tgaccatggc cgagcggtcc ttcgaggaaa agaagtacga cgaggcactg aaggagggga
    12001 tgaaggcacg ccgcctattg tgtgaaagct cctcagacac cgccgagcct gttaaggacg
    12061 cggtcatcgt caagatcccc aagccggaga cgaagtgcga aaaatgctcg gccacggtca
    12121 attccgacga cctgttctgt cgtaagtgcg gcgcgccgat cattatgaaa cgaagctgcg
    12181 cccactgcca ggccgagatg ggagacgggg acgtcttctg cccgaaatgc ggtcgcaggg
    12241 cctgaaggcc acaggctgta acattaatac atcaagacca attatcctgc gaatcaaatg
    12301 atcctggtta aattgggtgg aagcgtcata accgacaagg gccggtaccg caccttcgac
    12361 ccggagacga ccgatcgcct ggcggaggag atcgccagga ccgggcagga cgtcatggtg
    12421 gttcacggcg ccgggtcctt cggacacatg ttggccaagg agcaccggct acacctcggc
    12481 ctcaccgagg attctcaact gctcggcgcg tccc
//
LOCUS       DAOPZI010000039        12475 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_5657_length_12475_cov_9.034058, whole genome shotgun sequence.
ACCESSION   DAOPZI010000039 DAOPZI010000000
VERSION     DAOPZI010000039.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 12475)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12475)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12475
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5657_length_12475_cov_9.034058"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..392)
                     /locus_tag="PKM11_07115"
     CDS             complement(<1..392)
                     /locus_tag="PKM11_07115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020449176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HNX48307.1"
                     /translation="MARKPARMYRRLTGQAYTRREYMGGVPALRINTFDLGTTNGDFP
                     ITINMKVKETCQIRHTAMEAARIAANRVMSKTPGNNYHLKFRIYPHHVLRENKLATGA
                     GADRVSSGMRNSFGKNIGTAARVHAGQVV"
     gene            533..1027
                     /locus_tag="PKM11_07120"
     CDS             533..1027
                     /locus_tag="PKM11_07120"
                     /inference="COORDINATES: protein motif:HMM:NF012792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HNX48308.1"
                     /translation="MNVRYEVMTEEGLDLIGPLWLELRQMHRARSVNFKRELGSMSFE
                     RRRDQLLEKAAGGLMRVELARDEDGRAIGYCVSSIGPDMTGEVDSIFVTVAYRQMGIG
                     TALMNSALQWMDGLGTVRKVLLAIVGNEEVHSFYARFGFLPKSTLLEQAWRPGEMRDS
                     DKPI"
     gene            1062..1406
                     /locus_tag="PKM11_07125"
     CDS             1062..1406
                     /locus_tag="PKM11_07125"
                     /inference="COORDINATES: protein motif:HMM:NF015965.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48309.1"
                     /translation="MSRKKVSNNQVRGIARKRMTILVRMSENEALGGDMTRAKRYMTI
                     ARRISGRNKVPMPEGAMYCRHCSTPLVPGLNCRVRLRNHRIGTHCLECDSIRRTPYLM
                     EIKERRTCRQER"
     gene            1388..1678
                     /locus_tag="PKM11_07130"
     CDS             1388..1678
                     /locus_tag="PKM11_07130"
                     /inference="COORDINATES: protein motif:HMM:NF014087.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HNX48310.1"
                     /translation="MPPRTMKDVKRVGHGLRPTVHVGKEGVTDTLIEEIAQQVKNRKV
                     VKVRLLPSVEEDRKQVGEDLAARSKTVLIEVVGHTVLLCDRKYLEGKGEIGF"
     gene            1680..2951
                     /gene="serS"
                     /locus_tag="PKM11_07135"
     CDS             1680..2951
                     /gene="serS"
                     /locus_tag="PKM11_07135"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HNX48311.1"
                     /translation="MSEVLDVNVIRDDPEAIRAMLRNRTYSEDVLDKFLELDQGWRAA
                     VEEGNRLRKQRNEASLRIAKLGGTEKAEAVAEMKKVASRISELEATVVSLEAQRDEVI
                     LLIPNVPHITVPIGDSYEKNRVVMEFGKVTKFDFQPKDHIALGEDLDIIDFQRGVKVA
                     GSGFFVLKGDGARMERALINYMLDLHHQQGYTEVFPPVVVNRAAVIGTGQYPKMKDDM
                     YWCERDDLWLNPTAEVPVTNLHQDDILTREDLPINYTAYLPSFRREAGRHAEMKGMIR
                     VHEFNKVELVKFVLPDGSFQELETLLNDAQDVLRGLELPFRTLLLCTGDMGFASAKTY
                     DLESHAPGTGSWLEVSSCSCFTDFQARRARIKYRPEAHLKSEFVHTLNGSGLALPRTM
                     VSIMENNQDREGRIRIPKVLRPYMQGQELIE"
     gene            complement(2986..3273)
                     /locus_tag="PKM11_07140"
     CDS             complement(2986..3273)
                     /locus_tag="PKM11_07140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48312.1"
                     /translation="MEDEVIHMVSLNDLIEELDCSLEDFLDQVTLAIDLLEEGEQEEA
                     VEVLKGLEEDLFDFLGYEETDEGAEEEEEKEEVKEVVKEKPKKAPAKKGKK"
     gene            complement(3356..7513)
                     /locus_tag="PKM11_07145"
     CDS             complement(3356..7513)
                     /locus_tag="PKM11_07145"
                     /inference="COORDINATES: protein motif:HMM:NF013125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lamin tail domain-containing protein"
                     /protein_id="HNX48313.1"
                     /translation="MTDRGSMRALSRDRRGQMPFSLIAIVLIIVSSLSAALIADLRNG
                     SQEVGLTVGEVERMVELSDDAKEQVQDLAWRSLLISCGGDPINESAMTSRFHSDLEGR
                     ISSSFPVTRSGFTVKANVSGVKLSFMLLPLDQSLTVEKFTDKYVPAYVGLTGSIMVQV
                     SSDNGNLSREYLIEDQGKVPWPLLNDRMKGFERAVSNDLGDLDSMVNYMLESLAAYRA
                     VQGWGSVVIGEKGLAETITERDLTNAIDLGLIILQMVHFRQATPCYGISTDVLGGEGC
                     WRFVDESLREGGTIDPADVFLGLYGYDELDWRKVFAQALNSAIERLSLRWMESLGLLK
                     LFELVERSSEEVFSFANELIERTFDVDLAEEHFKKWLKEAFEEAGIPDTLYRFFGAGW
                     PEGTIDIEQMTFQLVGDDSEVTSIALGGLVALDIPQTDVLAWTGWGEFHEQYKKGTLE
                     ILGAIRREIASVSEQISRSMFLPKGELKLDPRDGVSFLDEMKASLTIALDQKSTWVRA
                     AMSTAGSTVMTADPLAEATKAEFMENRDIILGRQQALESMVSSVAEQLLSSALSNHQD
                     VPWDENLEQLKKLIVGDDAWGVYDSMERTFDEHAQFLQGYFLAGLSQGSSSGAMSSRM
                     GDVIARTGDPYAGISVVLSEDVTRLLSDISNGLRLRGNQMSVSIPSSPYFSLLGPDGR
                     AHQESLRVELTYPDENSQGSWLSSIITDPRNYRGSPDIDAQIHDTDILGSKAASYQSV
                     WKLTYSGAVCLTLSPGGEIGQVLPVELERHLAFGSDLSVAVLTGHALMGVSYININTL
                     GQQISDIIDSLLRPLQEGLGTLTSYLRTLYRMLQGAITSLVEMSGDVLDKLSKMLGSM
                     VEELQDFIRSSASVLESKAAKLLLGIIGERSLTLSFLGLDLTVKLKPKDLDYREVGVP
                     ASFTLAFKANDCRIDVTTRLIKGQGNLSLLTNASLRGADWTVSVVVDPFMDVFRHMVE
                     VRGLVDGACVELVMPEAVSYRKVSFSLSDIPGVGEILSNIPLPIPGLKGVVNAGVYLK
                     VLEGRTDQVVINEYELNPAGEDAGREWVELYNPTTEAVDLTGWTIETRHGVQGLGSLG
                     GVMMPRARMVYRFPEQALDNIGEGFPFEESLVLRDERGRRVDSAPFSTDCWNDERTWQ
                     RAKDAADRWEFKSGTKGSSNGRDLFTLLDLDTVERIYFSAITESLYQLSSGELSMEAL
                     ATTIETALLRMLERLTSNILDKEVVAGLFVEVAVSEAASIAKSGMRMEVIWRCGTLRD
                     ALHDLAGSARPLALSFGNPFQAYLDGLPSTNGIWLAMSAFGSVGVPKMICLPGYSTEV
                     RYQASVAVDLGVLAKVFGLRASGWSMEAGVKITGVPATAVPLFKAPYGTTLDIWLCKV
                     TVQGVTA"
     gene            complement(7564..8301)
                     /locus_tag="PKM11_07150"
     CDS             complement(7564..8301)
                     /locus_tag="PKM11_07150"
                     /inference="COORDINATES: protein motif:HMM:NF014080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX48314.1"
                     /translation="MNIVDVLRLDISDVEKEFAQIASALGNLGLSNYESRAYVALLLR
                     AHATAEDIAELAVIPRTSAYKSLQSLVTKGFAQCTEGRPAIYHPLDIEELRERTMNEM
                     NGMFAKLSSIKGLLSEKGTPELVFTIYGRKKVLMKIGEMLDSARETFMISSPKMQDIR
                     SDLSDRFKDAQGRGVKITIITEPGVKVPSANEIFRRKGLIATDVIVDGRIAMIATEDL
                     DLCGFSDNPLIAGHLENFLHMVKGSKK"
     gene            8408..9928
                     /locus_tag="PKM11_07155"
     CDS             8408..9928
                     /locus_tag="PKM11_07155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX48315.1"
                     /translation="MPKKTESLCPECKKIIIATISEKDGKVVMDKECAEHGHFSDVVW
                     SDVDMYLKSEGLSYDGVGVENPFIPKAKVCPNDCGLCDMHLSHTALANLDLTNRCNMK
                     CPICFANANQSGYVYEPSYDEVVKMMQVLRDSKPVPCPAIQFAGGEPTIYPQFVDVIK
                     KAKELGFAQIQVATNGIMFANDFEFLKASTEAGLNTIYLQFDGMNDDIYMISRARKML
                     DVKMKVIENVRKLQKRPSVVLVPVVVKGVTDSQVGPIFRYALENSDVIRGINFQPVSF
                     TGRINKEELAKQRYTLPDLVRDFEEQTHGEIKKSDWFPVPSVVPLSTLASAFVREPKV
                     TFTTHPHCGIATYLFIQDKGHVVPLTSFVDVEPLFKELFELSKKAEKAKLLFPSKVKV
                     YSLLKKYTHEDKMPEGLDMSTFLKLLGSLMDDKSKESLAKFSWKMMMIGGMHFQDLYN
                     YDIERVKRCAIHYVVPDGRIIPFCAYNGGPTYRDQVEKKFSVPIEEWRRTRGSEHT"
     gene            9941..10114
                     /locus_tag="PKM11_07160"
     CDS             9941..10114
                     /locus_tag="PKM11_07160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX48316.1"
                     /translation="MIVSIEKCMHCGACVGSCPQNAIYLNEIVLEFNENCNKCGRCVR
                     LCPAGALKMEGKE"
     gene            10111..11298
                     /locus_tag="PKM11_07165"
     CDS             10111..11298
                     /locus_tag="PKM11_07165"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HNX48317.1"
                     /translation="MKTDYDVIVVGGGPAGSMTAKHAAKKGARVLMIEKRQEIGASLR
                     CAEGVNKKGLAKAGVPVDKRWVSADIAGAKLVSPGGKVFRIDESQAGAEVGLVLERHL
                     FDKAMAADAARAGAEIWLKTAAVDVIKEGDKVVGVKARREGEPITLTAGCVVAADGFE
                     SQVARWAGIDTSLKTGDITTCYQYRMANLKTEPDYCEFIIGSVAPGGYIWVFPKGDDT
                     ANVGIGVLASKLKKPGDVKMYLDKWIKKDPRLSCGQPVEAIAGGVSVSPPVEQSVMNG
                     LILVGDSARIIDPITGGGIANGLLAGKFAGEVLGDCVQANDYSEAALMPYDKKWRDAM
                     ENRLWRNWMAKEKFLTLSDKTLDGVIDTLSTANVDKMSVHNILIAIKEKHPELVKEFE
                     ELI"
     gene            complement(11320..12252)
                     /gene="mvk"
                     /locus_tag="PKM11_07170"
     CDS             complement(11320..12252)
                     /gene="mvk"
                     /locus_tag="PKM11_07170"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HNX48318.1"
                     /translation="MSGRTWGASAPAKVILLGEHAVVFGKPAVSVAIGLRLRCKIRPA
                     AVSSLNGVPLTPQNYSYVSACLARHGAPPTAVLTDSDFPSGSGLGSSAAVTVALLAAL
                     NASKGDLKEDVVAREAFEVECEVQGRASPIDTSTCAHGNGILVQRQRGDGFLWEISMD
                     TRRWCVHDLPVPKMTLVIGFTGKSKPTGPLVAKVKRYVDHTTFARDIVSEIGDVTMEG
                     VKQMAQGDLEGLGRTMTKDHKLLAILGVSTRELDKMVSSVLPYSYGAKLTGAGGGGSM
                     VALTDQPQKVMEIIKNKGGQPFAADTGVPGVRIE"
     gene            complement(12263..>12475)
                     /locus_tag="PKM11_07175"
     CDS             complement(12263..>12475)
                     /locus_tag="PKM11_07175"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48319.1"
                     /translation="PDFMTDDMFTGLDHNLEITLVNKESKVDVLEMFEAALAKFEGEW
                     WNAALKELGGKSPDQAMQAMGRKYGL"
BASE COUNT         2734 a         3620 c         3591 g         2530 t
ORIGIN      
        1 actacctgac cggcgtgaac gcgggcggcg gtgcctatgt tcttaccgaa ggagttcctc
       61 ataccgctgg agacacggtc agcaccggcg ccggtggcga gcttgttctc ccttagaacg
      121 tgatgaggat atatcctgaa cttcaggtgg tagttgttgc cgggggtctt ggacatcacc
      181 ctgttggccg cgatacgggc ggcctccatg gcggtgtgcc tgatctgaca ggtctccttg
      241 accttcatgt tgatggtgat cgggaagtcc ccattggtgg tacccagatc gaaagtgttg
      301 atcctcaggg ctggaactcc acccatgtat tccctgcggg tgtaggcctg tcccgtgagc
      361 ctcctgtaca tccttgccgg ctttctggcc atatcatatc acctgtaatc tatcaatgcg
      421 acgggatggc tacattcata ttttcctata taaggctgat ggatgtgaag attagccata
      481 tctcgctgac cagagagaaa agcttcttgc atatgaggat atctatcaaa agatgaacgt
      541 tcgctacgag gtcatgaccg aggagggatt ggacctcatc ggtccgttat ggttggagct
      601 gcggcagatg caccgggccc ggtcggtcaa tttcaagagg gagctggggt ccatgagctt
      661 cgaacggcgc agggaccaac ttctggaaaa ggccgccggc ggattgatgc gagtggaact
      721 ggccagggac gaggatgggc gagcgatcgg atactgcgtc tctagcatcg ggccggacat
      781 gaccggggag gtggactcca tcttcgttac cgtcgcatat cgccagatgg gaatcggtac
      841 cgcattgatg aattcggccc ttcaatggat ggacggattg ggaaccgttc gcaaagtgct
      901 cctggccatc gtcgggaacg aggaggtcca ctccttctac gcccgcttcg gcttcctgcc
      961 caagagcacc ctgctggaac aggcctggcg accgggcgaa atgcgagatt cggacaaacc
     1021 tatttaacaa gatggcatta tcgcacctga aggataggcc tttgagcaga aagaaggtgt
     1081 cgaacaacca ggtgcggggc atcgcccgca agaggatgac gatcctggtc cggatgtcgg
     1141 agaacgaggc cctaggtggc gatatgacaa gggccaagag gtatatgacc atcgccaggc
     1201 gtatctccgg acggaacaag gtacccatgc ctgaaggggc gatgtattgc cggcactgct
     1261 cgacacctct cgttccggga cttaactgcc gggtccggct gcggaaccac cgcatcggca
     1321 cccactgtct ggaatgcgat agtatcagaa ggacaccgta tcttatggag atcaaggaga
     1381 gaaggacatg ccgccaagaa cgatgaagga cgttaagagg gtcggacatg gcctgcgacc
     1441 caccgtgcac gtgggaaagg agggggtcac cgacaccctc atcgaggaga tagcccagca
     1501 ggtcaagaac cgcaaggtcg tgaaagtgcg cctgctcccc agcgtggagg aggaccgcaa
     1561 gcaggtcgga gaggacctgg ccgcgcgttc caaaacggtc ctgatagagg tcgtgggcca
     1621 caccgtactg ctatgtgacc gtaagtatct ggaaggcaag ggagagatag gtttctaggg
     1681 tgagcgaagt gttggacgtc aacgtgatca gggatgaccc cgaggccatt cgggccatgc
     1741 tcaggaaccg cacctacagc gaggacgtgc tggataagtt cctggaactg gaccagggct
     1801 ggcgggcggc ggtggaggag ggcaaccgac tcaggaagca gaggaacgaa gcttccctgc
     1861 gcatagccaa gctcggcggc acggagaagg ccgaggcggt ggcggagatg aagaaagtgg
     1921 catcgcgcat cagcgaactg gaggccacgg tcgtctctct ggaggcccag agggacgagg
     1981 tgattctgct catcccgaac gttcctcaca tcacggtacc tatcggcgac agctacgaga
     2041 agaaccgggt ggtcatggag ttcggaaagg tcaccaagtt cgacttccag cccaaggacc
     2101 acatcgcact gggcgaggac ctggacataa ttgacttcca acgcggggtg aaggtcgccg
     2161 gcagcggctt cttcgtgctg aagggcgacg gggcccgcat ggagagggca ttgatcaact
     2221 acatgctgga ccttcaccac cagcagggct acaccgaagt tttcccaccg gtcgtggtga
     2281 accgggccgc ggtcatcggc accggacagt acccgaagat gaaggacgat atgtactggt
     2341 gcgagcgaga tgacctttgg ctaaacccaa cggcggaggt cccggtcacc aatctgcatc
     2401 aggacgacat cttgaccagg gaggacctgc ccatcaatta caccgcctac ctgccttcgt
     2461 tccggcgaga ggccgggagg cacgccgaga tgaaggggat gatccgggtg cacgagttca
     2521 acaaggtgga actggtcaag ttcgttctgc ccgacggctc gttccaggag ctggagacgc
     2581 tgctcaacga cgcccaggac gtgctgcgcg ggttggagct tccgttccga acgctcctgc
     2641 tgtgcaccgg ggacatgggc ttcgcttccg cgaagacgta cgatctggag tcgcacgcac
     2701 cgggaaccgg cagttggctg gaggtctcct catgcagctg cttcaccgac ttccaggctc
     2761 gccgggctcg tatcaagtat cgtcccgagg cgcacctgaa gagcgagttc gtgcacaccc
     2821 ttaacgggtc cggcctggcg ttgccgagga ccatggtctc cataatggag aacaaccagg
     2881 accgtgaggg acgcatacgg atacccaagg tcctcaggcc ctacatgcag ggacaggaac
     2941 tgatagaata ggaaaggtaa acggtttatg ggccgctagg cggccttact tctttccctt
     3001 cttggccgga gccttcttgg gcttttcctt cactacctct ttgacttcct ctttctcttc
     3061 ctcttcttcc gctccctcgt ccgtctcttc gtatccaagg aagtcgaaga ggtcctcttc
     3121 cagccccttc aaaacctcaa cggcctcttc ctgctcgcct tcctcaagaa ggtcaatggc
     3181 cagggtaacc tggtctaaaa agtcttccag gctgcagtcg agctcctcga tcagatcgtt
     3241 caggctaacc atgtgtatta cctcatcttc caatatcctt tgcaaataga taagacatcg
     3301 ggttcaggaa ctttgaaact ggggggacct tctctcggat cgaccgtccg ttccatcatg
     3361 ccgtcacccc ttggacggtg accttgcaca gccaaatgtc cagcgtcgtt ccgtacgggg
     3421 ccttgaacag cggaacggcg gtagccggca ccccggtaat cttgaccccg gcctccatcg
     3481 accatcccga ggctctcaga ccgaacacct tggcgagcac gccgaggtcc acggccaccg
     3541 aggcctggta tcggacctcc gtgctgtatc cgggcaggca gatcatcttc ggaacgccga
     3601 ccgagccgaa ggccgacatg gcaagccaga taccgttggt ggagggcagc ccgtcgagat
     3661 aggcctggaa gggattgccg aaggaaagag ctagcggccg ggcagaaccg gccagatcat
     3721 gtagggcatc ccgtaaggta ccgcaacgcc agatgacctc catcctcatt cccgatttgg
     3781 ctatcgatgc tgcttcggac accgctactt ccacgaacag cccggccacc acctccttgt
     3841 caagtatgtt cgaggtaagc ctttccagca ttcgcagaag ggcggtctcg atggtcgtcg
     3901 ccagggcttc catgctcagt tccccggagg agagctggta gagcgattcg gtgatcgccg
     3961 agaagtagat gcgctccacg gtatcgaggt ccaggagggt gaagaggtcc ctaccgttgg
     4021 acgagccttt cgtcccgctc ttgaactccc agcggtcggc cgcgtccttc gccctttgcc
     4081 aggtcctctc atcgttccag cagtccgtgg agaagggagc gctgtccacc ctccgtccgc
     4141 gctcgtccct gagcaccagg ctttcctcga acgggaaccc ctcccctatg ttgtccaagg
     4201 cctgctctgg gaaacggtac accattcgcg cccggggcat catgaccccg cccaatgacc
     4261 ccagcccctg aacgccatgc cgggtctcga tggtccatcc cgtgaggtcc accgcctccg
     4321 tggtgggatt gtacagctcc acccattccc gccccgcgtc ctcgccggcg gggttcagct
     4381 cgtattcgtt gatcaccacc tggtcggtcc gtccctcgag caccttgagg tataccccgg
     4441 cgttaaccac ccctttcaga ccagggatcg gaagcgggat gttagacaat atctccccca
     4501 cccccggtat gtcggatagg gagaaggaca ccttcctgta gctgaccgcc tcaggcatga
     4561 ccagttccac gcaggcccca tccaccaatc ctctgacctc caccatgtga cggaacacgt
     4621 ccatgaacgg atcgaccacc acggaaacgg tccaatcagc gccccgaagc gaggcgttgg
     4681 tgagcaggct aaggttacct tgacccttga tcagtcgggt agtaacgtcg atgcgacaat
     4741 cattggcctt gaaggctaac gtgaaggatg ccggcacccc gacctctcgg taatccaggt
     4801 ccttgggctt cagcttgacc gtcaggtcca agcccaggaa gctcaaggtc aggctcctct
     4861 cgccgatgat gcctaggaga agcttggcgg ccttggactc cagaacggat gcgctcgaac
     4921 ggatgaaatc ctgcagttcc tccaccatgg aacctaacat cttggagagc ttgtcaagga
     4981 catctccact catctctacc aggctggtta tggccccctg gagcatccgg tatagcgtcc
     5041 ggagataaga ggtcagggtc cccagacctt cctgtagcgg gcggagaagc gagtcgatga
     5101 tgtctgagat ctgctgaccg agcgtattga tgttgatgta gctcacaccc atcagggcat
     5161 gcccggtcag taccgccacg gaaagatcgg atccgaacgc cagatgtctc tccagctcca
     5221 ccggaaggac ctgccctatt tccccgccgg gagacagtgt gagacaaacc gctccagagt
     5281 aggtcaattt ccataccgac tgataggatg cggccttgga ccccaggatg tcggtgtcgt
     5341 gtatctgcgc gtctatatca ggcgacccgc gataattacg gggatcggtt atgattgagg
     5401 ataaccatga tccctgcgaa ttttcgtcgg gataggttag ctcgacccgg agggattcct
     5461 gatgcgcacg accgtctgga ccaaggagcg aaaagtatgg tgaagaaggg atcgagacgc
     5521 tcatctgatt tccccgtagg cgtaatccat tggagatatc ggacaacaat cgggtaacat
     5581 cttcactgag caccaccgag atacccgcgt atggatcccc ggtccgggcg atgacatcgc
     5641 ccatccggga tgacatcgca ccggaggaag agccttggct cagcccggcc aggaaatacc
     5701 cttgcaggaa ctgggcatgt tcgtcgaagg tccgctccat cgaatcgtaa acgccccatg
     5761 cgtcatctcc cacgatgagc ttttttagct gctccaggtt ctcgtcccaa ggaacgtcct
     5821 ggtggttgga gagggcggac gatagaagct gctccgccac actggatacc atggattcca
     5881 atgcttgttg cctgcccagg atgatgtctc ggttctccat gaactcggcc ttggtagcct
     5941 ctgccagagg gtcggcggtc atcacggtgg accctgctgt gctcatcgcc gctcggaccc
     6001 aggtactctt ctgatcaagg gcgatggtca gcgaagcctt catctcgtct aggaaggaaa
     6061 cgccgtcgcg agggtcgagc ttcagttcgc ccttcgggag gaacatgctt cgagagatct
     6121 gttccgacac tgaggctatc tccctcctta tggcccctag tatctccagc gtgcccttct
     6181 tgtactgttc atggaattca ccccagccag tccaggccag tacatcggtc tgggggatgt
     6241 cgagagcgac aaggccccct aaggcgatgg atgtgacctc gctatcatcc cccaccaatt
     6301 ggaaagtcat ctgctcgatg tcgatcgttc cttccggcca tccagcacca aaaaaacggt
     6361 agagcgtgtc aggtattccg gcctcttcga aagcttcctt gagccacttc ttgaagtgtt
     6421 cctcggccag gtccacatcg aaagtgcgtt cgataagttc gttggcaaag gagaacacct
     6481 cctcactaga cctctcgacg agctcgaaca gtttgagcag acctagggac tccatccacc
     6541 gcagggaaag gcgctcgatg gccgagttca aggcctgtgc gaacaccttg cgccaatcca
     6601 gttcgtcata gccgtagagg ccaaggaaca catccgcagg gtcgatggtg ccgccttccc
     6661 gcaggctctc gtcgacgaat cgccagcagc cttccccgcc aagaacgtcc gtgctaatac
     6721 cgtagcaagg tgtggcctga cggaaatgca ccatttgcag aattatcagc ccgagatcga
     6781 tggcgttcgt caggtccctt tcggttatcg tttccgccag gcctttctca ccgataacca
     6841 cgctccccca tccttgcacg gcgcgatatg cggccagaga ttccagcatg tagttcacca
     6901 tggagtctag gtcaccgagg tcgttggaaa ccgccctctc gaaccccttc atccggtcgt
     6961 ttaaaagggg ccagggaacc ttgccctggt cctcaattaa atattcacgg ctgagattgc
     7021 cgttgtccga ggagacctgg accatgatgg agccagtgag accaacataa gctggaacgt
     7081 acttatctgt gaacttttct accgtgaggc tttgatcgag gggaaggagc atgaaggaga
     7141 gcttcactcc gctgacgttg gctttcacgg taaacccaga ccgggttacc ggaaagcttg
     7201 aactgatgcg cccctcgaga tcactatgga aacgcgaggt catggcgctc tcgttgatgg
     7261 ggtcgccgcc gcaactgatc aaaagagatc gccaggccag gtcctgaact tgttccttgg
     7321 cgtcgtcgga aagttcgacc atgcgttcga cctcccccac cgtcaaacct acctcttggg
     7381 agccattgcg gaggtccgcg atcaaggctg cggagagact ggagacgatt atcagaacga
     7441 tcgcgatcag ggaaaagggc atctgtcccc ggcggtcccg ggataaagca cgcatcgagc
     7501 ctctatcggt catccctcct gaccacgacc tgacggataa aaagggggtg agctacaatc
     7561 aggttacttt ttagaacctt tgaccatgtg caggaagttc tcgagatgcc ccgcgatcag
     7621 tggattgtcg gagaacccgc ataggtctag atcttccgta gcgatcatgg ctattctccc
     7681 atccactatt acgtcggtgg cgatcaatcc ctttctacgg aaaatttcgt tggccgaagg
     7741 gaccttgacc cccggctcgg tgattatcgt gatcttcacc cctcttccct gagcatcctt
     7801 gaagcgatcg gaaagatcgg aacggatgtc ctgcatcttt ggcgaggaaa tcatgaaggt
     7861 ctctctggcg gaatcgagca tctcgccgat cttcatgagc actttcttcc ttccatagat
     7921 ggtgaacacc agttcggggg tccccttctc ggatagaagc cccttgatcg agctcaactt
     7981 ggcgaacatc ccgttcatct cgttcatggt cctttcgcga agctcctcta tgtccaaagg
     8041 atgatagatg gccggtcgtc cttccgtaca ctgggcaaaa cccttggtca ccaaggattg
     8101 cagtgatttg taggccgagg tacgtggtat gacggccagc tcagcgatgt cctcggccgt
     8161 agcatgcgcc cttagcaata acgcgacata ggccctagat tcgtaatttg acagacctaa
     8221 attccctaag gccgaagcta tttgcgcgaa ttccttttca acgtcactaa tatccagcct
     8281 tagaacatct acgatattca tgtcaagaca tgtagcagat gtcgctacat aaatattata
     8341 ttatcgagct gaagtatcag cctggggtgc aattttgatt gcaaaagaga gttcattacc
     8401 cagaggattg ccgaagaaga cggagtcgct ctgtcctgag tgcaagaaga tcataatcgc
     8461 taccatttca gaaaaggacg gaaaggtggt catggataag gaatgcgcgg aacacgggca
     8521 tttctctgac gtagtctggt cggacgtgga catgtaccta aaatccgagg gcctgtccta
     8581 tgacggagtg ggcgtggaga atcccttcat acccaaagcc aaggtttgcc ccaacgactg
     8641 cgggctctgc gacatgcacc tgagccacac cgcattggcc aatctggacc tgaccaaccg
     8701 ttgtaatatg aaatgcccga tatgtttcgc caacgccaat caatcgggat atgtttacga
     8761 acctagctac gacgaggtcg tgaagatgat gcaggtgctg cgtgacagca agcctgtgcc
     8821 ttgcccggcc attcagttcg ccggcgggga accgaccatc tacccgcagt tcgtggacgt
     8881 gatcaagaag gccaaggaac tggggttcgc ccagatccag gtggccacca acggcatcat
     8941 gttcgccaac gattttgagt tcctgaaggc ctccacggag gccggcctga acaccatcta
     9001 cctgcagttc gacgggatga acgacgatat ctacatgata tcccgcgcca gaaaaatgtt
     9061 ggacgtgaag atgaaggtca tcgagaacgt tagaaagttg cagaagcgcc cctcggtggt
     9121 tctcgttccc gtggtggtca agggggtcac cgacagccaa gtcggcccga tattcaggta
     9181 cgccctggag aactccgatg tcatccgcgg catcaatttc caaccggtgt ccttcacggg
     9241 aaggatcaac aaggaagaac tggcaaagca gaggtacacc ctgcccgacc tggtcaggga
     9301 tttcgaggaa cagacccacg gcgagataaa aaagagcgac tggttcccag tgcctagcgt
     9361 ggtaccgctg tcgaccctcg cctcggcctt cgtccgtgag ccgaaggtca ctttcaccac
     9421 ccacccccac tgcggtatcg ccacctatct gttcatccag gacaagggac atgtcgttcc
     9481 attgacctcc ttcgttgacg tagagccact gttcaaggaa ctgtttgagc tgtccaagaa
     9541 ggcggagaag gccaagttgc ttttccccag caaggtgaag gtgtactcac ttctgaagaa
     9601 gtacacgcac gaggacaaga tgcctgaggg actggatatg agcaccttcc tgaaacttct
     9661 aggctcgctc atggacgaca agtccaagga atccctggcg aagttctcct ggaagatgat
     9721 gatgatcggc gggatgcatt tccaggacct gtacaactac gacatcgaaa gggtcaagcg
     9781 ctgcgccatc cattacgtgg tacccgatgg aaggatcata ccattctgcg cctacaatgg
     9841 ggggccgacc taccgggacc aggtggagaa gaagttctcc gtacccatcg aggagtggag
     9901 acggaccagg ggatcggagc acacataagg aggtaccaaa atgatcgtga gcatcgagaa
     9961 gtgcatgcat tgcggcgcct gcgtgggttc ctgcccccag aacgccatct acctgaacga
    10021 gattgtgctg gagttcaatg agaactgcaa taaatgcggc cgctgcgtgc gcctgtgccc
    10081 cgccggcgcc ttgaagatgg agggaaagga atgaagaccg attacgatgt gatcgtcgtc
    10141 gggggcggtc ccgccggaag catgaccgcc aagcatgcgg ccaagaaggg agcccgggtc
    10201 ctgatgatag agaagcgcca ggagatcggc gcatccctgc gttgcgccga aggggtcaac
    10261 aagaagggac tggccaaggc cggtgttccg gttgacaagc gctgggtatc cgccgatatc
    10321 gccggagcta agctggtctc acccggagga aaggtcttcc gcatagatga gagccaggcc
    10381 ggagccgagg tcggattggt tctggagagg catctcttcg acaaggccat ggcagccgat
    10441 gccgcccggg ccggagcgga gatatggctc aagaccgccg ccgtggacgt catcaaggag
    10501 ggtgacaagg tcgtgggcgt caaggccaga cgcgagggcg agccgatcac cctcaccgcc
    10561 ggatgcgtcg tggccgcgga cggtttcgaa tcacaggtgg cccgctgggc tggtatcgat
    10621 acctccctca agaccggaga catcacgacc tgctaccagt accgcatggc caacctgaag
    10681 accgagccgg actattgcga gttcatcatc ggttccgtag ccccgggagg atacatctgg
    10741 gtgttcccca agggagacga cacggccaat gtcggcattg gcgttctggc ctccaagctc
    10801 aagaaacccg gggacgtcaa gatgtacctg gacaaatgga tcaagaaaga tcccaggctc
    10861 agctgcggac agcccgtgga ggctatcgcc gggggtgtat ccgtatcgcc gccggtcgag
    10921 cagtcagtga tgaacggcct aatactggtc ggggactccg cgcgcatcat cgaccccata
    10981 accggaggcg gcatcgccaa tggactactg gccggaaagt tcgccggcga ggtgctgggc
    11041 gactgcgttc aggccaacga ctactccgag gcggctttga tgccctacga caagaagtgg
    11101 cgcgacgcca tggagaaccg cctgtggcgc aactggatgg ccaaggagaa gttcctcacg
    11161 ctttccgata agaccctgga cggcgtgatc gatacgctat ccaccgccaa cgtcgacaag
    11221 atgtcggtgc acaacatcct gatagccatc aaggagaagc accccgagct ggtcaaggag
    11281 ttcgaggaac ttatctgaaa cctttttcct tgaaaccctt tattctattc taactccggg
    11341 aaccccggta tctgcggcga aaggctggcc gcccttgttc ttgatgatct ccattacctt
    11401 ctgcggctga tcggtcaagg ccaccatgct gcctccgccg ccggccccgg tgagcttggc
    11461 accgtaggaa tatggaagca cggatgagac catcttgtcc agttcccgtg tcgaaacccc
    11521 gagtatcgcc aggagcttgt ggtccttggt catggttcgc ccgaggccct ccagatcgcc
    11581 ttgggccatc tgcttgacgc cttccatggt cacgtcccct atctcactca cgatgtcccg
    11641 ggcgaaggtg gtgtgatcaa catacctctt caccttggcc accagcggac cggtaggttt
    11701 cgatttgccg gtgaagccga tcaccagggt catctttgga acgggcaggt cgtgaacgca
    11761 ccagcgacgg gtgtccattg atatctccca aaggaaaccg tccccgcgct gcctctggac
    11821 cagaatgccg ttcccgtgcg cgcaggtcga ggtgtctatc ggactggccc gcccctgaac
    11881 ctcgcactcc acctcgaacg cttccctggc caccacatcc tctttgagat cccctttcga
    11941 ggcgttcaag gcggccagga gggccacggt gaccgccgcc gatgagccca ggccggaccc
    12001 cgacgggaag tcggagtcgg tgagcaccgc ggtcggaggg gctccgtgcc tggctaggca
    12061 ggccgacaca tacgaatagt tttgaggcgt gagcgggacc ccgttcaagg aggagacggc
    12121 ggccggtcgg atcttacatc tgagacggag acctatggcc acggataccg ctggcttccc
    12181 gaacaccacg gcgtgctcgc ccagcaatat caccttggcc ggagccgacg cgccccaggt
    12241 tcgaccggac atctgacgac cttcacagac cgtacttgcg gcccatggcc tgcatggcct
    12301 ggtcggggct tttaccgccc agctccttca aggccgcgtt ccaccactcg ccctcgaact
    12361 tggccagggc ggcctcgaac atctccagca cgtccacctt gctttccttg ttcaccaggg
    12421 tgatctcgag attgtggtcg agacccgtga acatgtcatc ggtcatgaag tcggg
//
LOCUS       DAOPZI010000040        12457 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_5666_length_12457_cov_10.883487, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000040 DAOPZI010000000
VERSION     DAOPZI010000040.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 12457)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 12457)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12457
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_5666_length_12457_cov_10.883487"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            50..823
                     /locus_tag="PKM11_07180"
     CDS             50..823
                     /locus_tag="PKM11_07180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48320.1"
                     /translation="MRMVCTFCGAASTEGAMVCSACVEMVREELFLRNWSMDPRSDMR
                     SLGIRSACLRIGPSSQGEVLLRKGSDPYLLVERTLNAEDRSHLPTVLDHYLAGMGVGL
                     HLMGDEQLPLRPQVKEFLKVPDQMDFQGERWGRALLRLGNLLALSARDISRLPLGDDL
                     RKEMFRDRASRALAFYRRAAAVPTLGPISRTNTAMLRLWGGDMEALDDLKVAAIDDSG
                     RMQLAKAYWDLGREDEAAETVALTEDLQGSVLRLRRGCP"
     gene            820..3663
                     /locus_tag="PKM11_07185"
     CDS             820..3663
                     /locus_tag="PKM11_07185"
                     /inference="COORDINATES: protein motif:HMM:NF024824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HNX48321.1"
                     /translation="MSDLSEKLDQNEKQRLLEALRKLGVQEYRDLMISLMGGMGVRVQ
                     SAREQQSSLVIHGQGEVPYLVLASRAGFSDPELVVRALIEDAKADGRVPVFMSLQDLD
                     PGTLNLLENEEVSFADTSRFISLLQKYGLDEQLADKEDLKVLEDRGETCLPSLCKIEE
                     LLEEAEQRRRKGDRSGAVRVLDQALQIKPLNDTIWLTKASYLSEMGRAAEALVAANKA
                     AELRPGDAGTWFTIALIQNQLGDRERELAAYDNVLRINPGHAPAMLNKGATLFEMGRL
                     EWSLKVFTDMTHRYPQEPRGWNNRGLALKGMGKLLEAQASFEKANALDPDFEDPLINI
                     ARLREERGDMPGAVEGWKDVLRLVDSRADIWAHLGTCLKANQEYEDALTAFDRALRLD
                     PGLGNVQQERDELASQMHLEDEPETAPVEKMTLAEAIGTGEVAEPVISSEGPSPAEGS
                     TVQVPENEAALDPVPEADVREEVSENVPLQIAEENVALETVPEPVVPAEVPVQVAVQV
                     PEENVALETVPEPNLPAELPEEVSLQVHESEVALEQVPEHQLPAELPTDKELMVKDEP
                     GKLEKVPQNLPAQFQSGPLAIEPPADAGATLDAPSEDKEASIDTVDEAIVPQTPALPE
                     WPYEVSLPPLSPEPDERAKQEAALLLAAGKHERVVTQCDQALSQGADLELFRLKARAL
                     ISLNRGEEAAEALKEALRHAPGDSRTTMDLEAIFHRYGGDGGRLLQSLECQESLNRHA
                     LDSLEKKRYNDLIRLDEKKGDLPVRLSKSLALVSRGRYREASKILKALISEFPAYPEG
                     LSNLGVCMRFMGEYDYDQAIHLMKLALEVDPHSSDAMNNIGCTLFAAGKYEEAMEVFK
                     AAADEDRRPEYLLNLSNVQMALGDTASAKGSLTSALKMEESADVLYMLGVIAEGEEQY
                     KWALSLYQDALAKSPGFREAQTGIDRTKVLSRK"
     gene            complement(3713..3955)
                     /locus_tag="PKM11_07190"
     CDS             complement(3713..3955)
                     /locus_tag="PKM11_07190"
                     /inference="COORDINATES: protein motif:HMM:NF017088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HNX48322.1"
                     /translation="MRKFITELKGKTVMTNDGQILGMIDNFVVDTVTGDINHVLVVPA
                     EEIDSRLFRTDSHGRLVLPFSEMKDVRDVVVMSISR"
     gene            complement(4041..4607)
                     /locus_tag="PKM11_07195"
     CDS             complement(4041..4607)
                     /locus_tag="PKM11_07195"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48323.1"
                     /translation="MVKVLKPKGQVKRVDGSGAEPPKARTKRPAQFDLREESLRTLSQ
                     FYLGEMDLKMRMRQMSIASGQEPPEWMAALEILKDNIIKTEHPDLKLKMYQGIVDLLA
                     KVGQKEDLFVIQQIIARYNLKSFKDIGFAKVEIEVAKDACPVCRKMAGKRFGIEEAME
                     TMPIPCHDCGTEVDAVEGYCRCRYFAVF"
     gene            complement(4616..6823)
                     /locus_tag="PKM11_07200"
     CDS             complement(4616..6823)
                     /locus_tag="PKM11_07200"
                     /inference="COORDINATES: protein motif:HMM:TIGR01243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDC48 family AAA ATPase"
                     /protein_id="HNX48324.1"
                     /translation="MAESVLLRVAKAKDQNEVGLGRARLDMKTRKELGVEAGQIIEIT
                     GKKMTVARVFRAQQEDEGKDIIRIDGVLRSNAGVSIGERVTVAKADPQPASKVVLAPA
                     ISQKKRVNSVTFGAGTDELVRKGLLGRPLVKGDEIMIPNMAWGVTLAPYMVASTVPNG
                     VVTVAEHTEMIVRSEATEEKDTFVPSITYDDVGGLDEVLQRIREMIELPLKHPELFER
                     LGIDAPKGVLLYGPPGTGKTLLAKAVANESGASFYSILGPEIMSKWYGGSEENLREKF
                     EEASKNAPSIIFIDEIDSIAPKRDDSAHEAERRVVAQLLTLMDGMTDRGQVIVIGATN
                     RQDALDPALRRPGRFDREIEVGVPTYQGRKEILQIHTRGMPLDEKVSLDQYAQVTHGF
                     AGADLSALAREAAMKCLGRFVPNMNLDSAIPQEILSQMKVTVEDFDAALKEIEPSAMR
                     EVMVEVPNIGWSDVGGLDEVKRQLKEMVEMPLDNPEAFKRMGIRPSQGVLLYGPPGTG
                     KTLLAKAVANESNANFISIKGPEIMSKWYGESEKAVREIFKKAKQVAPSIVFLDEIDA
                     IAPRRGVYEGSRGYDTLVNQLLTSLDGLTAREGVTVIAATNRPDIIDQALLRPGRFDR
                     LIFVPVPDAPARRAILQVHTRIMPLKDVNIEDLVLRTEGFVGADLENLCREAAMAALR
                     ENKDSMTVEMRHFESAFKNVRPSVDKESVKTYDMLSKNLHKARGGIDDLGIFR"
     gene            6912..7784
                     /locus_tag="PKM11_07205"
     CDS             6912..7784
                     /locus_tag="PKM11_07205"
                     /inference="COORDINATES: protein motif:HMM:NF014046.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ARMT1-like domain-containing protein"
                     /protein_id="HNX48325.1"
                     /translation="MDFSAECAPCLLRRILFQTRLVDPSKEEEIMFSCLRLVAEEWRP
                     GMRSATLATKVHRMCYDTLGVADPYAALKAESNRVAFSLLPRAEELVNSSQDRLKAAC
                     LVAIAGNVMDFGIGGYEHPEELRHLFDDLVAEEPEPDDLDRLREILQSSKEVLYLFDN
                     CGEIVLDLPLLRELKSMGLRVTGVVKGEPIITDATWEDLSISGADKILDECLTTGVFA
                     IGLDLDQAPKELQDAFERVDLVIAKGMANFEALSGTDVKPIAHLLRSKCLPVASAIGA
                     RKDRNVIRVFEREV"
     gene            7786..8820
                     /locus_tag="PKM11_07210"
     CDS             7786..8820
                     /locus_tag="PKM11_07210"
                     /inference="COORDINATES: protein motif:HMM:NF012695.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NDP-sugar synthase"
                     /protein_id="HNX48326.1"
                     /translation="MSKVKQAVILAGGEGTRLRPLTTTRPKPLLPVLGVPCIEYVIRS
                     LADAGIEQVFLACGYRSEDIRAALGGGDRFGVEIEMAFEKEPMGTAGAVKLLEDRLNG
                     TFVVGSGDTLTDADLGDLIDFHIRKGAEATMGLTEVERPEQFGIVGVSAEGRIDRFKE
                     KPRSEEVFSRVINAGTYVLEPEVLRMIPAATKYDFSKNLYMDMLDKKRGLYATPLKGY
                     WKDIGRPSDLYLANMDMASRRPTTSAPAGARAVGSCYFGRDVTASSATVMDSAIGHGC
                     VLEGTIETSLLLDRVSVGKGASLNGCVIGEGCRIGAAAALRDCVLGDGAVISAGTVLA
                     ATNIEARASI"
     gene            8852..9745
                     /locus_tag="PKM11_07215"
     CDS             8852..9745
                     /locus_tag="PKM11_07215"
                     /inference="COORDINATES: protein motif:HMM:NF013088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HNX48327.1"
                     /translation="MAEASPRTRALLMLAGMIWGTSFVAGKFAVEGTDPYLFSAMRAL
                     VAAVSILPVFFLYKFDYSIFKSKAVWGIAFLNAAGLLLQNVGLTYTTASNTVLLVDIN
                     VVIVAVLAAIILKEHLNRRTVIGLVLGMSGVALIATKGDISSLGGGNLIGDLLVFTAG
                     VAWAMYIVFTTKELRKGYELVHFTSAMILLTAVFAVPIGLFMTADYSVGAGGISLALY
                     SGIFCTTVAFMLYNVGLKSLGATTTSIILLVEMVFGLFFSFLLLGERPDLITLMGGSL
                     ILLAIVVISFKGLDRSRRRRA"
     gene            complement(9742..10131)
                     /locus_tag="PKM11_07220"
     CDS             complement(9742..10131)
                     /locus_tag="PKM11_07220"
                     /inference="COORDINATES: protein motif:HMM:NF040320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48328.1"
                     /translation="MSYKQFDVYVQDRPGEVSRVVEALAHNAVNIRGIATDIGAGRPR
                     VHIITDDDNSARSALKSAQLEFEEQEVIVVSMADKPGELAKITRKLARGGVNINSLFM
                     LGPMTPLEEVAMTVDRLEAAKKLLEFS"
     gene            10220..11125
                     /locus_tag="PKM11_07225"
     CDS             10220..11125
                     /locus_tag="PKM11_07225"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025017.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HNX48329.1"
                     /translation="MPQALRPFAVTVNWNRAKDTLECVDSLLQGNPGTEVVVVDNGSA
                     DGSPALLREKHPGLMVIENLQNLGYVKGANIGIRAALEKGATHILIINNDAIAHPGMV
                     NELLELFQRYPSAGVAGPKIFYFGTDVMWFNGGHFNALLGFSTHPLMDRPDDGGDLER
                     EVHYITGCAMMVRSEVFRDVGLFDEDFEIYAEDLDLCLRAKEKGYCSWLVPKATAEHK
                     VSLSTGVVGTNLMTPYRSYYYGRNMLVMVRKRMRGGRFITGFVGQTFILLPYYFLLIS
                     MQKARGSFLQYLKGYAHAVVWMVRS"
     gene            complement(11126..12229)
                     /locus_tag="PKM11_07230"
     CDS             complement(11126..12229)
                     /locus_tag="PKM11_07230"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX48330.1"
                     /translation="MAQKTYDDLTVILPTYNEGGNIQSMLETLVSLYPGVSIVVADDN
                     SKDETSDLVRSFSLKHPKARLLSRDPNDRGLTASIMEGISETRTKWFVVMDADFQHPP
                     ESVGGMYGLLTEGADMAVGKREDKTSLSFSRMLASWGANALAKSYLAVMRRPTTEDTM
                     SGFFGGRTDLCQEVVTKHGRKFERAGFKVLFDILKFLPRDTVVKELEFQFSSRRAGKS
                     KLSSRVILSILRQCGPAGKAAALGVNFLFINMLGRYISALALGLAFTFAMMETLSVTY
                     DDRLINSTILAFVLALAYLVVANKYLFSHGKRDRLIIGAKMVFTGFSGFMISVFFFYM
                     LLSSDQAVHTWPMFLGFGIAYLWNTLSSVIPEK"
BASE COUNT         2371 a         3733 c         3899 g         2454 t
ORIGIN      
        1 cttgccagcg acaaggatta atccccgacg ggcaatatcc ccccagggga tgcgtatggt
       61 atgcacgttc tgcggcgccg cttcgaccga aggggccatg gtatgctcgg cttgcgttga
      121 gatggtcaga gaggagctct tcctgaggaa ttggtccatg gaccccaggt ccgacatgcg
      181 ttcactgggc atccggagcg cctgcttgcg gatcggcccc agctctcagg gcgaggtact
      241 tctgcggaaa gggagcgatc cctaccttct ggtggagagg actctgaatg ccgaggaccg
      301 ctctcacctg cccacggtcc tggaccatta cctggcgggt atgggggtcg gccttcatct
      361 catgggggac gagcagttgc cgctacgccc ccaggtgaag gaattcctca aggtcccgga
      421 ccagatggac ttccaggggg agaggtgggg cagggccctg ctgcgtctag ggaacctgct
      481 ggcgctgagc gccagggaca tttcaaggct tccgttgggc gacgaccttc gtaaggagat
      541 gttccgcgat agggcgtccc gggcgttggc cttctaccgc cgggccgcgg cggtgccgac
      601 gctggggcct atttcccgga ccaacacggc gatgctcagg ctctggggag gcgacatgga
      661 agcgctcgac gatctcaagg tggccgcgat agacgacagc ggacgtatgc aattggccaa
      721 ggcctattgg gacctgggac gggaggacga ggccgctgaa acggtcgcat tgaccgagga
      781 cctgcagggg tccgtcctgc gcctgaggag gggatgcccg tgagcgacct ctccgagaag
      841 ttggaccaga acgagaagca acgtctcctg gaggcgctgc gaaagctcgg ggttcaggag
      901 tatcgggacc tcatgatctc cctgatgggc ggaatgggcg tccgggtgca atcggcccgg
      961 gagcagcaga gctcgctcgt gatacacggg cagggagagg ttccctatct cgtgctggcg
     1021 tcgcgcgccg ggttctccga cccggagctg gtggtgcgtg ccctgatcga ggacgccaag
     1081 gccgacgggc gagtcccggt gttcatgtcc ctgcaggacc tggaccctgg cactcttaat
     1141 cttttggaga acgaggaggt gtccttcgcc gacaccagcc gattcatctc gctcttacag
     1201 aagtacggtc tggacgagca gctcgcggac aaggaggacc tcaaggtttt ggaggaccgc
     1261 ggcgaaacct gcctgccttc cctgtgcaag atcgaggagc ttctggagga ggcggagcaa
     1321 aggcggagga agggggaccg ttccggcgcc gttcgcgttc tggaccaggc cctgcaaatc
     1381 aaacccctca acgacaccat ctggctcacg aaggccagct atctctcgga gatgggaagg
     1441 gcggcagagg cgttagtggc ggcgaacaag gccgccgagc ttcgtccggg ggacgccggg
     1501 acctggttca ccatcgccct gatccagaac cagctcgggg accgggaaag ggagctggcc
     1561 gcctatgata acgttctacg catcaaccct ggacatgccc cggcgatgct taacaaaggt
     1621 gcgacgttat ttgagatggg ccgtctggag tggtcgttga aggtgttcac cgacatgacg
     1681 caccgctatc cccaggagcc gcgcggctgg aacaatcgtg gcctggcgtt gaagggcatg
     1741 gggaagctgc tggaagcgca ggcctccttc gagaaggcca acgcactgga ccctgatttt
     1801 gaggatcccc tgatcaacat agcccgcctg cgcgaggagc ggggcgacat gcctggcgcc
     1861 gtcgaaggtt ggaaggacgt gctgcggctc gtcgattccc gggccgacat ttgggcccac
     1921 ctcggcacct gtctgaaggc caaccaggaa tacgaggatg ccctcaccgc cttcgaccgg
     1981 gcgctgaggc tggatccagg cctcgggaac gttcagcagg agagggacga gctggcctcg
     2041 cagatgcacc tggaagatga gccggagacc gccccagtcg agaagatgac tttggctgaa
     2101 gctatcggca ccggggaggt cgccgaaccc gtcatttcgt ccgaggggcc gagcccggcg
     2161 gagggatcga ccgttcaagt tccggagaat gaagcggcat tggatccagt tcccgaagca
     2221 gatgtccgtg aagaggtctc cgagaacgtt cctttgcaga tcgccgagga gaatgtggcc
     2281 ttggagacgg ttcctgaacc agttgttccc gctgaggtcc cggtgcaagt ggccgttcag
     2341 gtcccagagg aaaatgtggc cttggagacg gttcccgaac cgaacctccc cgccgagctt
     2401 cccgaggagg tctcactaca ggtccatgag tcggaagtgg ccttggaaca ggttccggaa
     2461 catcagctgc cggccgagct gccgacggac aaggagctga tggtgaagga cgagccgggt
     2521 aagctggaga aggtccccca gaacctcccg gcgcagttcc agagcggtcc cctggccatc
     2581 gagccgccgg ccgatgctgg ggctacgcta gacgcaccta gcgaggataa ggaggcctcc
     2641 attgacacgg tggacgaggc catagtaccg caaaccccgg cgttaccgga gtggccgtac
     2701 gaggtatccc tgcccccgct ctctccggaa ccggacgagc gggcgaagca ggaggcggcc
     2761 cttctgctgg ccgcgggaaa gcacgagagg gtcgtcactc aatgcgacca ggctctgagc
     2821 caaggggccg acctggagct gttcaggctg aaggcccggg cgctcatctc cctgaaccgg
     2881 ggagaggagg cggccgaggc gctcaaggaa gcgctgaggc acgctcctgg tgattcacgc
     2941 acgacgatgg acctggaggc gatattccac cgctacgggg gcgatggcgg caggttgctg
     3001 cagtccctgg aatgccagga gtcgctgaac cgtcacgcac tggactccct ggagaagaag
     3061 cgttacaacg accttatacg cctggacgag aagaaggggg atctgccggt acggctgtcc
     3121 aagtccctgg cgttggtctc tcggggaaga tatcgggagg cgtccaagat cctgaaggcc
     3181 ctcatctccg agttcccggc ctatcccgag ggattgagca acctcggggt gtgcatgcgc
     3241 ttcatgggag agtacgatta cgaccaggcc attcacctga tgaagctggc tctggaggtg
     3301 gacccgcata gttcggacgc catgaacaac atcgggtgca cgctgttcgc cgccgggaag
     3361 tacgaggagg cgatggaggt cttcaaggcc gccgcggacg aggaccgccg gccggagtat
     3421 ctgttgaacc tcagcaacgt ccagatggcc ctgggcgaca ccgcctcggc caagggcagc
     3481 ctgacctccg ccctcaagat ggaggagtcg gccgacgtgc tgtacatgct gggagtgatc
     3541 gcggaaggcg aggagcagta caaatgggcg ctcagcctgt accaggatgc cctggccaag
     3601 agccccgggt tccgcgaggc gcaaacgggg atcgaccgca ccaaggtgct ttccaggaag
     3661 tgaacggcta aagctgaaaa gataaaagat ggagaaaagg tagggtttcg gtctagcggg
     3721 agatgctcat gaccactacg tcacgaacat ccttcatctc gctgaacggg agcaccaggc
     3781 ggccgtggct gtcagtgcgg aacaggcggc tgtcgatctc ctcggcaggg accaccagca
     3841 cgtggttgat atctccggtg acggtgtcga ccacgaagtt gtctatcatg cccagtatct
     3901 gaccgtcgtt ggtcatgacc gtcttcccct tcagctcggt tatgaacttc ctcatttgcg
     3961 caccccaaac agatgttccg attagctatc gcatgagatt gagcctattt atagatttat
     4021 agaatgcttg tctggacacc tcagaacacc gcgaagtagc ggcatctgca gtacccctcc
     4081 accgcgtcca cctcggtgcc gcaatcgtgg caggggatgg gcatggtctc catggcctcc
     4141 tcgatcccga acctcttccc ggccatcttc ctgcacacgg gacaagcgtc cttggccacc
     4201 tctatctcca ccttggcgaa cccgatgtcc ttgaacgatt tcaggttgta gcgggcgatg
     4261 atctgctgga tgacgaacag gtcctccttc tgaccgacct tggccagaag gtccactatg
     4321 ccttggtaca tcttcagttt gaggtccggg tgttcggtct tgatgatgtt gtccttgagt
     4381 atctccaggg cggccatcca ctccggcggt tcctggccgg aggcgatgct catctggcgc
     4441 atccgcatct tgaggtccat ctcccccaga tagaactggg agagggtgcg caggctctcc
     4501 tcccgcaggt cgaactgcgc gggcctcttc gtcctggcct tgggcggctc ggcgcccgaa
     4561 ccgtccactc tcttgacctg acccttgggc tttaaaacct tgaccatcat ctcacctacc
     4621 tgaatattcc caggtcgtcg atgccgcccc gggccttgtg caggttcttg ctcagcatgt
     4681 cgtacgtctt cacggactcc ttgtccaccg acggtcggac gttcttgaag gccgactcga
     4741 agtgccgcat ctccaccgtc atgctatcct tgttctcccg caaggcggcc attgccgcct
     4801 ctcggcacag gttctccagg tcggctccca cgaacccttc cgtcctcagg accaggtcct
     4861 cgatgttgac gtccttcaac ggcatgatcc gggtgtgcac ctgcaggatg gccctccgag
     4921 ccggggcgtc cgggacggga acgaatatca accggtcgaa gcggccgggc cgcagtagcg
     4981 cctggtcgat gatgtccggg cgattggtgg cggcgatgac cgtcacgcct tcccgggcgg
     5041 tgaggccgtc caatgaggtc agcaattgat tgaccagcgt gtcgtacccc ctggaaccct
     5101 cgtacacccc gcggcggggg gcgatggcgt cgatctcgtc aaggaacact atggacggag
     5161 cgacctgctt ggccttcttg aatatctccc gcacggcctt ctcgctctcc ccgtaccact
     5221 tggacattat ctccgggccc ttgatgctta tgaagttggc gttcgattcg ttggctaccg
     5281 ccttggccaa tagcgtcttg ccggttcccg gcggtccgta gaggagaacg ccctgggacg
     5341 gcctgattcc catccgcttg aaggcctccg ggttgtccag gggcatctcc accatctcct
     5401 tcagttgtct cttcacctcg tccaggccgc ccacgtcgct ccagccgatg ttaggcacct
     5461 cgaccatcac ctcgcgcatg gccgaaggct cgatctcctt cagcgcggca tcgaagtcct
     5521 ccacggtcac cttcatctgg gagagtatct cctggggtat ggcgctgtcc aggttcatgt
     5581 tggggacgaa ccttcccagg cacttcatgg ccgcctcgcg cgccaacgcg gacaggtcgg
     5641 ccccggcgaa gccgtgggtg acctgggcgt actggtccag gctgaccttc tcatccaacg
     5701 gcatgccgcg ggtgtggatc tgcagtatct ccttccggcc ctggtatgtc ggcaccccga
     5761 cctcgatctc ccggtcaaat cgtcccggtc gccgcagggc cgggtccaaa gcatcctggc
     5821 ggttggtggc gccgatgacg atgacctggc cgcggtcggt catgccatcc atgagggtga
     5881 gcagctgggc caccacccgg cgttccgcct cgtgggcgga atcgtccctc ttgggggcga
     5941 tggaatctat ctcgtcgatg aatatgatgg acggagcgtt cttggaggcc tcctcgaact
     6001 tctcccgaag gttctcctcg ctgcctccgt accacttgga cattatctcc ggtcccagga
     6061 tggagtagaa ggacgccccg gactcgttgg ccaccgcctt ggccagcagc gtctttcccg
     6121 ttcccggcgg gccgtacagg agcacgccct tcggcgcgtc tattcccagg cgctcgaaca
     6181 gctccgggtg cttcaagggc agctcgatca tctcccggat gcgctgcagc acctcgtcca
     6241 atccgcccac gtcatcatag gtgatggacg ggacgaaggt atccttctcc tcggtggctt
     6301 ccgatctgac gatcatctcg gtgtgctcgg cgaccgtcac caccccgttg ggtacggtgg
     6361 aggccaccat gtacggggcg agggtcactc cccaggccat gttggggatc atgatctcat
     6421 cgcccttgac caacggtcgt cctaggaggc ctttgcgcac cagttcgtca gttcccgccc
     6481 cgaaggtgac gctgttcacc cgcttcttct gggatatcgc cggggccagg accaccttgc
     6541 tggccggctg ggggtccgcc ttggccacgg tgaccctctc cccgatggag acgccggcgt
     6601 tggagcgcaa tacgccgtct atgcggatga tgtccttccc ttcgtcctcc tgctgggccc
     6661 ggaacaccct ggccacggtc atcttctttc cggtgatctc aatgatctgg cccgcctcta
     6721 cgcccagctc cttgcgggtc ttcatgtcca gccgggcccg gcccagaccg acctcgtttt
     6781 ggtccttggc cttagctacc cggagaagaa ctgactctgc catgattatc aaggtcgaat
     6841 cctttctctg gatattaagt ttgcatcacg acgacgaaag gaataataga gcgccctcac
     6901 ctcccccgca tatggacttc tccgccgaat gcgctccctg tctcctgcgc cgcatacttt
     6961 tccagaccag gctggtcgac ccttccaagg aggaagagat catgttctcc tgcctgcgac
     7021 tggtggcgga agaatggagg ccgggcatga ggtcggcgac cctggccacc aaggtgcacc
     7081 ggatgtgcta tgatacgctg ggagtggcgg acccctacgc cgccctgaag gcggaatcga
     7141 accgggtggc cttctccctg cttcccaggg cggaagaact ggtgaacagc tcccaggacc
     7201 gcctgaaggc cgcctgcctg gtggccatag ccggcaacgt catggacttc ggcatcggtg
     7261 gctacgaaca tccggaggag ctgaggcatc tattcgacga tctggtcgcc gaggaaccgg
     7321 agcctgacga cctggaccgt ctgcgcgaga tactacagag ctcaaaagag gtgctatatc
     7381 tgttcgacaa ctgcggggag atcgtgctgg acctcccgct gctcagggag ctgaagagca
     7441 tgggcctccg ggtgaccggg gtggtcaagg gcgaaccgat aatcacggac gccacctggg
     7501 aggacctctc catcagcggc gcggacaaga tactggacga atgtctgacc accggggtgt
     7561 tcgccatcgg tctggacctc gaccaggcgc cgaaggagct ccaggacgct ttcgaaaggg
     7621 tcgacctggt catcgccaag ggcatggcca acttcgaggc cctgtccggg acggacgtca
     7681 agcccatagc gcacctgttg cgcagcaagt gcctgccggt ggcctcggcg atcggagcga
     7741 ggaaggaccg caacgtgata agggtgttcg aacgagaggt gtgagatgtc caaggtgaag
     7801 caggccgtca tattggcagg tggcgaaggc accagacttc ggccgttgac caccacccgg
     7861 ccgaagccgt tgctgccggt gttgggcgtt ccctgcatag agtacgtgat ccgttcactg
     7921 gcggacgccg ggatcgaaca ggtgttcctg gcctgcggct atcgctccga ggacatccgt
     7981 gccgcgctgg ggggaggcga tcgcttcggc gtggagatcg agatggcctt tgagaaggaa
     8041 cccatgggca ccgctggcgc ggtcaagctg ctggaggacc gactgaacgg aacgttcgtg
     8101 gtcggcagcg gggacactct cacggacgcg gaccttggcg accttatcga tttccacatc
     8161 cgcaaggggg cggaggccac catggggctc accgaggtgg aacgcccgga acagttcggc
     8221 atagtcggcg tctccgctga gggaaggatc gaccggttca aggagaagcc ccgcagcgag
     8281 gaggtgttct cccgggtcat caacgccggg acgtacgttc tggagccaga ggttctgagg
     8341 atgatacccg cggctaccaa atacgacttc tccaagaacc tctacatgga catgctcgac
     8401 aagaagcggg gattgtacgc cacgcctctg aagggctact ggaaggacat cggtagaccg
     8461 tccgacctct atctggcgaa catggacatg gcctcccggc gccccacgac atcggcgccc
     8521 gctggagcga gggcggtcgg aagctgctat ttcggaaggg atgtcaccgc ttcatcggcg
     8581 acagtgatgg acagcgccat cgggcacggg tgcgttctgg agggaacgat cgaaaccagt
     8641 ctgctcctgg accgggtgag cgttggaaag ggagcttcgc ttaacggttg cgtcatcggc
     8701 gagggttgcc gcatcggtgc cgcggcggcg ctgcgggatt gcgtgctggg agatggggcc
     8761 gtgatatccg cgggaacggt actggctgca acgaacatcg aggcccgggc ctccatctga
     8821 gataaatatt cggaccggat agagggcgaa catggccgag gcatcccccc gaacccgcgc
     8881 cctgctaatg ctggcaggca tgatctgggg cacctcattc gtggctggga agtttgcggt
     8941 ggagggtacc gacccctatc ttttcagcgc catgcgggcc ctggtggcgg ccgtctcgat
     9001 cctgccggtg ttcttccttt acaagttcga ttattccata ttcaagagca aggccgtctg
     9061 gggcatcgcg ttcctcaacg cggccggcct gctgttacag aacgtcggtc ttacctacac
     9121 gacagccagt aacaccgttc tgctggtcga tatcaacgtg gtcatcgtgg ccgtgctggc
     9181 cgcgatcatc ctcaaggagc atctgaaccg gcgaacggtg atcgggctgg tcctaggaat
     9241 gtccggggtg gcgctcatag ccaccaaggg tgacatctcg agcctgggcg gggggaacct
     9301 catcggcgat ctgctggtgt tcaccgccgg ggtggcctgg gccatgtaca tcgtgttcac
     9361 caccaaggag ctgaggaagg gctacgagct ggtgcatttc acctcggcga tgatacttct
     9421 gaccgcggtg ttcgccgtgc ccatcgggct cttcatgacc gccgactact ccgtgggcgc
     9481 cggtggcata tcgctggccc tgtactctgg gatattctgc accaccgtgg ccttcatgct
     9541 gtacaacgtc ggcctgaagt ccctgggggc caccaccacg tccatcatcc tgttggtgga
     9601 gatggtgttc gggctgttct tctccttcct gctgctcggg gagaggccag acctcatcac
     9661 cctgatgggc ggttcgctca tactgctcgc tatcgtggtg atctccttca aagggctgga
     9721 taggtcccga cggcgccggg cctaagagaa ctccagcagc ttcttggccg cctcgaggcg
     9781 gtccacggtc atggccacct cttccaaggg ggtcatgggg cccagcatga acagggaatt
     9841 gatgttcacg ccgccccggg ccagcttcct ggttatcttg gccagttcac caggcttatc
     9901 ggccatggag accacgatga cctcctgctc ctcgaactcc agctgcgcgc tcttcaacgc
     9961 gctgcgggcg ctgttgtcgt cgtcggtgat tatgtgcacc ctcggccttc ccgcgccaat
    10021 gtccgtagct ataccgcgga tgttgacggc gttatgggcc agggcctcca ccacccggga
    10081 gacctccccc ggacggtcct gcacgtacac gtcgaactgc ttgtaggaca tcctattcag
    10141 attgatgcac caggcaatta atactttgga aggaagggac ggagcattag atttatagct
    10201 cgagcccata cctatcggca tgccccaggc cctcaggcca ttcgccgtaa cggtgaattg
    10261 gaaccgagcg aaagacacct tggagtgtgt cgactcgctc ctgcagggaa accccgggac
    10321 cgaagtggtg gtggtggaca acggttccgc cgacggatcg cccgccctgc tccgggagaa
    10381 gcatccaggc ctcatggtga tcgagaacct gcagaacctc ggttacgtca aaggggccaa
    10441 catcggcatc cgagcggccc tggaaaaagg ggcgacccat atactcatca tcaacaacga
    10501 cgccatcgcc catccgggca tggtcaatga gctgctggag ctgttccaga ggtacccgtc
    10561 cgccggagtg gccggcccca agatattcta cttcggaacg gacgtcatgt ggttcaacgg
    10621 agggcacttc aacgcccttc tgggtttttc cacccatccc ctaatggacc gaccggacga
    10681 cggaggggac ctggagcgcg aagtgcacta catcacggga tgcgccatga tggtccgttc
    10741 ggaggtcttc cgggacgttg gtctctttga cgaggacttc gaaatctacg ctgaggacct
    10801 ggacctctgt cttagagcaa aggagaaagg ttactgctca tggctggtgc ccaaggccac
    10861 ggcggagcac aaggtgtcgc tgtctaccgg ggtcgtaggc accaacctga tgacccccta
    10921 tcgttcgtac tactacggta ggaacatgct ggtcatggtc cgcaagagga tgcgcggtgg
    10981 gcgattcatc accggtttcg ttggccagac gttcatacta cttccttact acttcctgtt
    11041 gatcagcatg cagaaggccc gagggtcctt cctccaatac ctcaaaggat acgctcacgc
    11101 cgtagtttgg atggtgcgtt cctgatcact tctcaggtat gacgctgctg agggtgttcc
    11161 acagataggc gatcccgaaa cccaggaaca tcggccaagt gtgcaccgct tgatcagagg
    11221 acagcagcat gtagaagaag aacacgctga tcatgaagcc ggagaagccg gtgaagacca
    11281 tcttcgcgcc aattatgagg cggtcccgct tgccatggga gaagaggtac ttgttggcca
    11341 cgaccaagta ggccagggcc agcacgaacg ccagtatcgt ggagttgatc aggcggtcgt
    11401 cataggtcac gctcagggtc tccatcatag cgaaggtgaa cgcgagtccc agcgccaagg
    11461 cggatatgta tcggcccagc atgtttatga agaggaaatt gacgcctaac gcggcggcct
    11521 ttccggccgg cccgcattgc ctgaggatcg agagaatgac cctcgaggac agcttggact
    11581 ttccggcccg acgggaggag aactggaatt ccagctcctt gaccaccgtg tcccggggca
    11641 ggaacttgag tatgtcgaag agcactttga aaccggcccg ctcgaacttg cggccatgct
    11701 tggtgacgac ctcttggcag aggtcggtcc gtccgccgaa gaatccgctc atggtgtcct
    11761 cggtggtcgg ccgtctcatg acggccaggt atgatttggc cagggcgttc gcgccccagg
    11821 aggccagcat gcggctgaag ctgaggctgg tcttatcttc acgtttaccg acggccatgt
    11881 ccgcgccctc ggtcagaagg ccgtacatgc cgcctacgga ctccggaggg tgctggaaat
    11941 cggcgtccat gaccacgaac cacttggttc ttgtctcgga gatgccctcc attatactgg
    12001 cggtaagccc ccggtcgttc ggatcgcggc tcaggagcct ggccttggga tgctttaagg
    12061 aaaaggagcg gaccaggtcc gaggtctcgt ccttggagtt gtcgtcagcg accactatcg
    12121 acactcctgg atagagcgaa acgagggtct ccagcatcga ctggatgttc cctccctcgt
    12181 tatatgtggg aaggatgacg gtcaaatcgt cgtaggtctt ctgcgccatc ccaatcctca
    12241 tcacaagaat ttttaagcat atttatagat tgttaggttt agaatactta accgagcagg
    12301 actccggttc ttacaatatt tatgcgtgtt cccctttctc ctatcgatgc tgaccatatc
    12361 ggccggggtg tgcgcttaca acgaggagaa gaacatcctc aagtgcctgc gctccctcag
    12421 ctcacagaag ctcaaaggaa aggagctggt tgagatg
//
LOCUS       DAOPZI010000041        11400 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_6491_length_11400_cov_9.552314, whole genome shotgun sequence.
ACCESSION   DAOPZI010000041 DAOPZI010000000
VERSION     DAOPZI010000041.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 11400)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 11400)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11400
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_6491_length_11400_cov_9.552314"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            83..1246
                     /gene="folP"
                     /locus_tag="PKM11_07235"
     CDS             83..1246
                     /gene="folP"
                     /locus_tag="PKM11_07235"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: protein motif:HMM:TIGR01496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HNX48331.1"
                     /translation="MARVRTYRNFQEAWGEWRRLGIPDRAFTRFDLASRQFLFVDSVS
                     KEEVSALQEELAPKKVTVLPCRGDRAVIAITPLTLESLMVSGASPMVMEIGEALRYRH
                     DIEPPLFEWSGGFLKLSKPRVVGILNVTPDSFSDGGQSFDADTAVDCAMAMKEEGADI
                     IDIGGESTRPGSTPVSSDEEWSRISDVVRRVSEEVGLPVSVDTRRPDVARKALRAGAV
                     MVNDISGLREEMIEVVRDEGAAAIVMHMRGEPSNMQEDTRYVDVVGDVYAFLENRVKK
                     AIAAGIPAERLAIDPGLGFAKDIDGNLEIMSRLDEFRSLGRPVLLGASRKTFLGKIAG
                     GDPDDRLEASLAAVSVACWQGVHLFRVHDVKETVRTLKAASAMRAGISPRSLR"
     gene            complement(1224..1418)
                     /locus_tag="PKM11_07240"
     CDS             complement(1224..1418)
                     /locus_tag="PKM11_07240"
                     /inference="COORDINATES: protein motif:HMM:NF021415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2116 family Zn-ribbon domain-containing
                     protein"
                     /protein_id="HNX48332.1"
                     /translation="MSLLPEHSHCLHCDDPVDVGQEYCSEECKATAESEAKKERTKNM
                     LFLGLAATILIVITIVVTLG"
     gene            complement(1452..2039)
                     /locus_tag="PKM11_07245"
     CDS             complement(1452..2039)
                     /locus_tag="PKM11_07245"
                     /inference="COORDINATES: protein motif:HMM:NF014669.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HNX48333.1"
                     /translation="MQVFDTVHGWRRATSAPLYRWREESSIVTKVSAAFVLALVMALA
                     AQVRIVLPFTPVPFTGQVLVVLLGAAVLGRYGALGQGMYLGMGAGLGWFSGMAGFAAL
                     LGPTGGYLLGFVLASVVLGEMVERRKDWSLGRVLTAMSLGVLIIYAFGAAQLALFLGL
                     DVTEAIVLGVVPFVIVDALKVLISAGAGTMFLRPA"
     gene            2107..2523
                     /locus_tag="PKM11_07250"
     CDS             2107..2523
                     /locus_tag="PKM11_07250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48334.1"
                     /translation="MGFSALMWKVFGEEGVMIRFGALWKQRMIDLSKRRKDRDRFLAL
                     LDKAEISHYLDIHQKLHVFRMELPVECTAEDVEFLKGFVQRIVKSTEYPMVELDDDEQ
                     KAILIISAEEPVDEHATRMSSWYKMKQDEDAKRGAN"
     gene            complement(2520..3629)
                     /gene="trpD"
                     /locus_tag="PKM11_07255"
     CDS             complement(2520..3629)
                     /gene="trpD"
                     /locus_tag="PKM11_07255"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HNX48335.1"
                     /translation="MDIDLREFGASVDALIRGEHIGRQRARDMFREVLLDQQPDLQQG
                     AFLAALTSSKPTPEEIAGSWEAIFEIDTLKARPEVDGYLVENCGTGMDRIKTFNVSTL
                     ASVVAAAGGVYMAKHGARAITSKCGIVDMAETLGVDVECDVSVVKRSVEVAGIGLFNG
                     MSAKVHPQALYRILSQIRFGTILNVAGSLANPASPEIGVRGVYSKELVMPLAKTMREM
                     GYRKGIVAHGLDGSGERGMDELSTLGRSIIAEFHEDGEVSSYEISPKQMGLAIGEERD
                     ILSTLDRDTEALRFIRVLMGIERGSRRDMVALNTAPILYLNGNASSLENGVVKALDIL
                     ESGKGYEKLKDWVRAQNSEDPQLKIERLERMAERA"
     gene            complement(3641..4654)
                     /locus_tag="PKM11_07260"
     CDS             complement(3641..4654)
                     /locus_tag="PKM11_07260"
                     /inference="COORDINATES: protein motif:HMM:NF012335.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HNX48336.1"
                     /translation="MRAALMRSPGMLDVDEVDDPIMPEGGVLLKVRACAVCGTDIKML
                     EAGHRDLTYPRIPGHEVTAQVLDTDSAMFRHGDLVQVWPGETCGHCVHCRAGNDHLCA
                     QVKIMGFNTDGGMAEMLAVSDPSRLVPIGQADPVMLTLAEPLACCINAQEKLRVGEGD
                     SVLILGGGPMGCLNAFLAKRRGAERVMLSEPVLERLSQVPKGLFDDVTQPKGEELAEM
                     VSRGTDGGGADVIIPCTPNIRLDRGVLDLLAPGGRLCVFSGPRREDSPLPFDLRDVHY
                     RELTVVGSYGNASRHGREAVRLLSEGADLSWMFTGKYGLDEVRQAFGHASGRTGQKAI
                     ITF"
     gene            4784..6511
                     /locus_tag="PKM11_07265"
     CDS             4784..6511
                     /locus_tag="PKM11_07265"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48337.1"
                     /translation="MVRRTYIAVALAFMMLAVSLTIPVTGDDTGDVRRFTSGTAGSAI
                     SDLQGSELVPSNISTRSAEGLLFNISVTFTYDLLDASESAPCAGAYVQLRMKGIGSFS
                     TVRSGHTDANGTVAFYGLAAGTYLVRIETDDDRWVRVADGSQSTPPTFHWNTQQFTVS
                     SQTDIEYRITDGTRGAWAVYSDLRDGGAWLDGLTGWERSQVTVVWPEGDWPHSHGDEI
                     HLPADEDFAEAVWRRDIALHEYAHCVHYELRGGSFPEGNGPDPHYIDSESSPGFAFTE
                     GWAQFFERAVDGDPERMDGSSLESTVFADGTYGHGDTGDMDGLIVEGAVASVLWDLYD
                     GTNASDRPSGSTRGDFIDKEFSTLWNIMYDQQPESLEDIKRAWPVRDVNVTAVFRNSR
                     VPMELDPPSNPTSFISSHEIGEGSGDSTISVIWSGASDRGSGVLGYSILISTDANGTP
                     DLVMDSIAGSYTSYSLSPGTYYLHIRTVDQDGNWAEDVYTIGPFVIDEGAVPVNEPLI
                     REGDLRQALFGLMIVLAIVVSLLMLVIFMDKKKPVPPPPMPVSYICRYCGRFDHGGEF
                     CPYCGGRLR"
     gene            6516..6974
                     /locus_tag="PKM11_07270"
     CDS             6516..6974
                     /locus_tag="PKM11_07270"
                     /inference="COORDINATES: protein motif:HMM:NF024304.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HNX48338.1"
                     /translation="MRKAEREIKDQKELEDLIRRVEVCRLAMVDDGEPYIVPMNFGYR
                     DGYLFFHCAREGRKLDVLRKNPRVCFELEADVHLVKGEKACQWSTSYQSVIGWGTATI
                     SLDEKDVKEGLEVLMSHYTRGPLDFDPRSLSLTAVIKVKVERMTGKRSKR"
     gene            complement(6964..7677)
                     /locus_tag="PKM11_07275"
     CDS             complement(6964..7677)
                     /locus_tag="PKM11_07275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HNX48339.1"
                     /translation="MSKVKRKIIKIDEEKCTGCGECVLSCAEGAIVIKDGKAKVVKDM
                     FCDGLGACLGHCPENALSIEEREADPFDEEAAMEHVEASKKGPPQACSSSRPMMIMTD
                     SKPMSAEDNPSQLRNWPIQLHLAPEVTPAYKNASLLIAADCTGFSLGNVQRDFIAGRI
                     AIIGCPKLDDVQAYIDKLARIFKNNEIKDLTLIRMEVPCCGGLQRIVHEALRISGKKL
                     PLQEFIVERYGGKVVKVTA"
     gene            7785..9410
                     /locus_tag="PKM11_07280"
     CDS             7785..9410
                     /locus_tag="PKM11_07280"
                     /inference="COORDINATES: protein motif:HMM:TIGR00704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HNX48340.1"
                     /translation="MAAISWELLFAIVPGLILFLYGIENFSKEIINSVGERFRETLGK
                     LTKDRWRGAAFGALLTGTVQSSAATTVIAVSLVNAGTISFAASLGVIVGANIGTTLTA
                     QLVAFKLTSFGPLFILIGFVWGLIGGRYKFIGKPLFYFGLVFFGLELVSNSLDPIRED
                     PAILSLISNLDNFFIALLVGVVFTTAVQSSSVTSGLMVVLASSGLLTLEQAIPVLLGA
                     NIGSTTTTLFASAKMDLWARRAAIAHLLFNVAGVLIFIPLAGLLATVVTDLTPDVGQQ
                     VANAHLIFNVITAIVFLVLLKQFEKVVVRVVPGDEKEVLFRPRFLTKEMPEDNGQAFH
                     LIEQELGHGLEVTKDLLDASFSSLSVKDKRAKQKVTKLESLNDYLDDEIADAILRMSR
                     RSLKGDEGLRTTLLVRMSNLMERLGDHAEDIGDLATGFREKGRAVPKEQLDQLSVVFE
                     KLRGNLELLGEDVLQVNEGTKATIRNETLSMSARINDIYSEHLERMRDASVPSDSTLL
                     ELLTIMESANEKVRELAALASDYAKLAPRTVDR"
     gene            complement(9415..10980)
                     /locus_tag="PKM11_07285"
     CDS             complement(9415..10980)
                     /locus_tag="PKM11_07285"
                     /inference="COORDINATES: protein motif:HMM:NF014443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HNX48341.1"
                     /translation="MSTSYNKARRWFGQLAYYFDRLNVDVNSIFDKVARKESAIPHIF
                     GVLMLYMAIALVFPYAVALYYGEDPRPWIFPILLCLISGILLLMRYRSPENTRPTEAM
                     FVVATGWLALTVMGAIPFVLYGMGVVDAVFEAMSGFTTTGSSIMTNIESWPKSILFWR
                     SFSHWLGGAGIIMIFVTVLPMLGVGGRNLFKNEFPGLDVQNFSARIQEEARKFHYIYG
                     FLSLMMLVLLLFTGIGVFDSFCVMFSTMGTGGLSPHSDSIAYYASSNVEWIVIIFMFL
                     ASTNFYLHFQAITTRDPNRYFRNSEFRLYLGIILAATAIITVFMWGKEFTDIEQGVRT
                     SMFQVVSLMSSTGFSTANYIFWDQAVVFLLLALIIIGGSTGSTAGGIKVARFFLTREF
                     IASALHKTIHPRSIFTVKIDGRPLSQEALSSVVAMVLCYFATAIVAVVALILLGIDPT
                     TSISAAIATLSNAGPGLGSIGPYGSYGGLPDAAKLVLTFTMWAGRLEFISVLVLFTPV
                     FWKELMRYREKYV"
     gene            complement(10991..>11400)
                     /locus_tag="PKM11_07290"
     CDS             complement(10991..>11400)
                     /locus_tag="PKM11_07290"
                     /inference="COORDINATES: protein motif:HMM:NF014171.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="TrkA C-terminal domain-containing protein"
                     /protein_id="HNX48342.1"
                     /translation="HLGVSKVISRYSKREYEEIFGMSGIDASVGYYHVVANEIIKETV
                     HNYEVMLLLEKFSEEFFDLKVTAGSRIIGKRIADIDMPKMSAIALVVKDGKALIPSPD
                     TVIEEGDKVFIYALQSAIAKLEWMFKANIPVGP"
BASE COUNT         2302 a         3402 c         3466 g         2230 t
ORIGIN      
        1 cctgaaggcc ggcgcgtccg gacgaccggc gccggaaata atcgacctgg tgcaattggt
       61 cgataggctt ctgtgaggaa acatggctcg agttcgcacc tatcgaaatt tccaggaggc
      121 ttggggagaa tggcgcaggc tgggaatacc ggaccgcgcg ttcacccgtt tcgatctggc
      181 atctcggcag ttcctgttcg tagattccgt cagcaaggaa gaggtcagcg cgctccagga
      241 agaactggcg cctaagaaag tgaccgtgct gccgtgccgc ggagatcgag cggtgatagc
      301 catcacccca ctgaccctgg agagcctgat ggtgagcggc gcctcgccaa tggtcatgga
      361 gataggtgag gcgttgcgtt accgccacga catcgaaccg cctttgttcg agtggtcggg
      421 aggtttttta aagttatcga aaccgagggt cgtaggcatt ctgaacgtga ccccggattc
      481 tttctccgac ggcggacaga gctttgatgc cgacaccgcc gtggattgcg cgatggccat
      541 gaaggaagag ggcgcggaca taatcgacat cgggggagaa tcgacccgtc ccggctcgac
      601 gccagtatca tcggacgaag agtggtcccg gatatctgac gtggttagaa gagtgagcga
      661 ggaggtcggt cttcccgtgt ccgtggatac ccgccggccg gacgtcgcca gaaaggcgct
      721 tcgcgccgga gcggtgatgg tgaacgacat ctctggactg agggaagaga tgatagaagt
      781 ggtccgtgac gaaggtgcgg ccgctatcgt catgcacatg cgaggcgagc cgtccaatat
      841 gcaggaagac accaggtacg tggacgtggt gggggacgtt tacgccttcc ttgaaaatag
      901 ggttaaaaag gccatcgccg ccggtatccc cgcggagcgt ttggccatcg atcccgggct
      961 ggggttcgcc aaggacattg acggaaattt ggagataatg tcccgtctgg acgagttccg
     1021 ttccctgggc cgcccggtgc tcctgggggc gtccaggaag accttcttgg ggaagatagc
     1081 cggtggagac ccggacgatc ggctcgaagc aagcttggcc gcggtgtccg tcgcctgctg
     1141 gcagggcgtt cacctgttcc gggttcatga cgtaaaagag acggtcagaa cgctgaaagc
     1201 ggcaagcgcc atgagagctg gtatcagccc aaggtcacta cgatagtgat cacgatgagg
     1261 atcgtcgccg ccaggccaag gaacaacatg ttcttggtac gctccttttt cgcctcgctc
     1321 tccgccgttg ccttgcactc ttcggagcag tactcctgac caacgtcgac cgggtcgtcg
     1381 cagtgcaggc agtgagagtg ttcggggagc aggctcatgt catctccaaa ggaaagggga
     1441 atgataaggg tttaggcggg acgcaggaac atcgttcccg ctccggcgga tatcagcacc
     1501 ttaagagcgt ccacgatgac gaacggaaca acgccaagga cgatcgcctc cgtgacgtcc
     1561 agacccagga agagagctag ctgcgccgcg ccgaaggcgt agatgatcag aacgcccagg
     1621 gacatggcgg tcaggacccg acctaagctc cagtccttcc ggcgctccac catttcacca
     1681 agaacgacgg acgccagaac gaaaccgagc aggtatccgc cggtcggtcc cagcagggcg
     1741 gcaaaaccgg ccatgccgct gaaccagcct agaccggcgc ccattcccag gtacatcccc
     1801 tggccgagag cgccgtaacg gcctagtacg gccgcgccaa gcagaaccac caatacctgg
     1861 ccggtgaacg gcacgggggt gaacggcagc acgatgcgca cctgcgccgc caacgccatg
     1921 acgagcgcca gaacgaacgc cgcgctgacc ttggtgacga tgctggactc ctccctccat
     1981 ctgtaaagag gtgcggacgt cgctcttcgc cagccgtgga ccgtgtcaaa cacttgcatg
     2041 gttatcgcag tatgaaagac cgccaaataa acatttcctg agcgagggca agctttaatt
     2101 gccagcatgg ggttttcggc cctcatgtgg aaggtcttcg gtgaggaagg ggtcatgatc
     2161 aggttcgggg cgctctggaa gcagaggatg atagatctgt ccaagcgccg caaggaccgc
     2221 gaccggttcc tcgccctcct ggacaaggcg gagatctcgc actatctgga cattcaccag
     2281 aagctgcacg tcttccgcat ggagctgccg gtggagtgca ccgccgagga cgtggagttc
     2341 ctgaagggct tcgtgcagcg catagtcaag agcaccgagt accccatggt cgaactggac
     2401 gatgatgagc agaaggccat cctgataata tccgccgagg aaccggtgga cgagcacgcc
     2461 acccgcatgt ccagctggta caagatgaag caggacgagg acgccaagag aggagcgaac
     2521 taggccctct cggccatccg ttccaacctt tctatcttta gctggggatc ctcggagttc
     2581 tgcgccctca cccaatcctt cagtttttcg taaccttttc cgctctccag aatgtctaag
     2641 gcctttacga cgccgttctc cagcgacgaa gcgttgccgt tcaggtacag tatcggagcg
     2701 gtgttcaggg ccaccatgtc ccttcgggaa cctcgttcaa ttcccatcaa tacccggatg
     2761 aagcgcagcg cctccgtgtc tcggtccagg gtgctcagga tgtccctctc ctcaccgatc
     2821 gccagaccca tttgcttcgg cgatatctcg taactgctga cctccccgtc ctcgtggaac
     2881 tcggcgatga tggaccttcc gagcgtggag agctcgtcca tgcccctctc cccgcttccg
     2941 tccagtccat gagcgacgat gcccttgcgg tagcccatct ccctcatcgt tttcgccaac
     3001 ggcataacca gctccttaga atagacccct cggacgccta tctccggtga agccgggttg
     3061 gccaatgacc cggccacgtt gagtatcgta ccgaagcgta tctgcgagag gatgcggtac
     3121 agcgcctgcg ggtgcacctt ggcgctcatg ccgttgaaga gccctattcc cgccacctcc
     3181 acgctgcgct ttaccaccga gacgtcacat tccacgtcca cgcccagcgt ctccgccatg
     3241 tccacgatgc cgcatttgga cgttatcgcc cgggcgccgt gcttggccat gtagacgcct
     3301 ccggcggcgg ctaccacgga cgcgagggtg ctcacgttga aggtcttgat gcggtccatg
     3361 ccggtgccgc agttctccac cagatatccg tcgacctccg gtctcgcctt cagcgtgtcg
     3421 atctcgaata tcgcttccca gctgccggcg atctcctccg gcgtgggctt ggaggacgtt
     3481 agagcggcca agaacgcccc ctgctgcagg tccggctgtt ggtcgagaag gacctcccgg
     3541 aacatgtccc tggccctctg gcgtcctata tgttctcccc tgatcagcgc gtcgaccgac
     3601 gctccgaact ccctgagatc gatgtccatg agatcctctc ctagaacgtg atgatcgcct
     3661 tctgcccggt gcgcccggag gcgtgtccga aggcctgtcg cacctcatcc aaaccatatt
     3721 ttccggtgaa catccaggag aggtccgccc cttcgctcag taatctgacc gcttcccgac
     3781 cgtgccggct ggcgttcccg tagctaccga ccacggtgag ctcccgatag tgaacatctc
     3841 gaaggtcaaa gggcagcggg gagtcctccc gacggggccc ggagaagacg cacagacggc
     3901 cgccaggcgc caacaggtcg aggacgccgc ggtccaggcg gatgttcggc gtgcagggga
     3961 tgatgacatc ggcacctccg ccgtccgtac cgcggctgac catttccgca agctcctcgc
     4021 cctttggttg tgttacgtca tcgaaaagac ctttcggcac ctggctcaga cgttccagca
     4081 ccggctcgct gagcatcacg cgctcggcgc ctcgtcgctt ggccaggaac gcgttcaaac
     4141 agcccatcgg ccctccaccc aggatcagaa cggaatcccc ctcacccacg cggagcttct
     4201 cctgggcgtt gatgcagcag gccaacggtt cggccaacgt caacatcacc gggtcggcct
     4261 ggcctatcgg caccaggcgg gacgggtcgc tcacggccaa catctcggcc attccgccgt
     4321 ccgtattgaa gcccatgatc ttcacttgag cgcaaagatg gtcgttgccg gcccggcaat
     4381 ggacgcagtg gccgcacgtt tcgcctggcc acacctgcac caggtccccg tgacgaaaca
     4441 tggcgctgtc ggtatccaga acctgagcgg tgacctcgtg tcccggtatg cggggatacg
     4501 taaggtcgcg atgcccggcc tccagcatct tgatgtccgt gccgcacacc gcgcaggccc
     4561 ggaccttcag cagcaccccg ccctccggca ttatcgggtc gtcgacctcg tccacgtcca
     4621 gcatgccagg cgatcgcatc aatgccgctc tcatgttctc acctaagttg agttggatat
     4681 atcatccaat tatataatcg atacgaactt ctcctgaccg cttattgaca tcgttcaagt
     4741 cccatggtga ggaatttaaa ccagtagcta ccttgaccgt ccaatggtgc gtcggaccta
     4801 tatcgccgtg gctctggcct tcatgatgct ggccgtgagc cttaccatcc ccgtgacagg
     4861 ggatgatacg ggcgacgtcc ggagattcac ctccggaacg gctggctccg ccatctcaga
     4921 ccttcaaggt tcggaacttg tcccttccaa catatcgacc cggtccgctg aaggtctcct
     4981 cttcaacatc agcgtcacgt tcacctacga cctgttggac gcgtcggaga gcgccccatg
     5041 cgccggtgcc tatgtccagc tgagaatgaa agggatcggc tccttcagca ccgtgcggtc
     5101 cggtcatacc gacgccaatg ggacggtagc cttctacgga cttgcggccg gaacgtacct
     5161 ggtgcgcatc gagacggacg acgaccgttg ggtccgggtg gcggacggct cccagagcac
     5221 accgcccaca ttccattgga acacccagca gttcaccgtg agctctcaga cggatatcga
     5281 gtaccgcata accgatggga cgcgtggagc atgggcggtg tatagtgatt tgcgggacgg
     5341 aggggcgtgg cttgacggcc tcaccggttg ggagcgctcc caagtgaccg tggtgtggcc
     5401 cgagggcgat tggccccatt cccatggcga cgagatccat ctgccggcgg acgaggactt
     5461 tgcggaggcc gtctggagaa gggacatcgc tctgcacgag tacgcccatt gcgttcatta
     5521 cgagctgcga ggtggtagct tcccggaagg gaacggccct gatccgcatt acatagacag
     5581 cgagtcgtcc ccggggttcg ccttcaccga gggttgggcg cagttcttcg aaagggcggt
     5641 ggacggcgat cccgagagaa tggacggcag ttcgttggag agcaccgtct tcgctgacgg
     5701 aacttacgga cacggagaca ccggtgacat ggacggcctc atcgtggaag gggcggtggc
     5761 cagcgtgctc tgggacctct acgatggaac gaacgcttcg gaccgcccgt ccggcagcac
     5821 ccggggggac ttcatcgaca aggagttctc caccctctgg aacataatgt acgatcagca
     5881 gccggagagc ctggaggaca tcaagagggc ctggcccgtg cgagacgtca acgtcaccgc
     5941 ggtgttccgc aactcgcggg tcccgatgga gctggacccg ccgagcaatc ccacctcgtt
     6001 catctcttca catgagatcg gagagggttc cggggacagc accatcagcg tgatctggtc
     6061 gggagcgagc gaccgcggga gcggcgtgct ggggtatagc atactgatca gcaccgacgc
     6121 caacggaacg ccggacctgg tgatggacag catcgccggt tcgtacacct cctattcgtt
     6181 atcgccagga acttactatc tgcacatcag gacggtggac caggacggca actgggcgga
     6241 ggacgtgtac accatcggcc cctttgtgat agacgagggc gcggtgccgg ttaacgaacc
     6301 actgatacgg gaaggcgacc tgcggcaggc gctctttggg ctgatgatcg ttctggcaat
     6361 tgtcgtctcg ctccttatgc tggtcatatt catggacaag aagaagcccg taccgccgcc
     6421 tccgatgccc gtgtcgtaca tctgccgcta ctgcgggcgt ttcgatcacg gcggggagtt
     6481 ctgcccctac tgcggcggaa gactgaggtg agggaatgag gaaggcggag cgggagatca
     6541 aggaccagaa ggagctggag gacctcatcc ggcgggtgga ggtgtgccgc ttggcaatgg
     6601 tggacgacgg ggaaccgtac atcgtgccca tgaacttcgg atatcgtgac ggatacttgt
     6661 tcttccattg cgcccgggaa ggccgcaagc ttgacgttct tcgtaagaac ccccgggtgt
     6721 gcttcgagct ggaagcggac gtgcatctgg tcaagggcga aaaggcttgc caatggtcga
     6781 ccagttacca gagcgtgatc ggctggggga cggccacgat atcattggac gagaaagatg
     6841 ttaaggaagg actggaggtc ctgatgtccc attacaccag aggaccgctc gatttcgacc
     6901 ctcgctccct gtcgctgacc gcggtgataa aggtaaaggt ggaaaggatg accggcaagc
     6961 ggtctaagcg gtgaccttga ccacctttcc gccgtagcgc tccacgatga actcctgcag
     7021 cgggagcttc ttgccactga ttcggagggc ctcgtgcacg atgcgctgaa gaccgccgca
     7081 gcagggcacc tccatgcgga tcagggtgag gtccttgatc tcgttgttct tgaatatcct
     7141 ggccagctta tcgatgtacg cctggacgtc gtccagcttg gggcagccga ttatggcaat
     7201 acgtccggca atgaaatcgc gttgcacgtt gcccagggag aaaccggtgc aatcggcggc
     7261 tatgagcagc gaggcgttct tgtaggcggg cgtgacctcc ggcgccagat gcagctgtat
     7321 cggccagttc ctcagctgag agggattgtc ctcagcggac atgggcttcg agtccgtcat
     7381 gatcatcatc ggccgggagg agctgcaggc ctggggcggt cctttcttgc tagcctccac
     7441 atgctccatg gccgcctcct cgtcgaacgg gtcggcctcc ctctcctcta tcgatagggc
     7501 attctccggg caatgcccga ggcaggcgcc gagaccgtcg cagaacatgt ccttgaccac
     7561 cttggccttg ccgtccttta tcactatggc cccttccgcg caggacagga cgcactcgcc
     7621 gcaaccggtg cacttctcct cgtcgatctt gattatcttc cgcttgacct tggacatggc
     7681 ggacgttcca tggagctggt cttttaagcg ttttgccctg cgtcgtccga aggtcacgaa
     7741 gaacatcgta aaggtaatct acccggtgca gttatgaatc gccgatggcc gccatttcct
     7801 gggagcttct gttcgcgatc gttcccggcc ttatactgtt cctgtacggt atagagaact
     7861 tcagcaagga gatcataaat tccgtcggtg agcggttccg ggagaccctg gggaagctga
     7921 ccaaggatcg ctggagaggg gcggccttcg gagcgctgct caccggtacg gtgcaatcca
     7981 gcgccgcgac gaccgtcatc gccgtcagcc tggtcaacgc gggtacgatt tccttcgcgg
     8041 ccagcctggg agtgatcgtg ggcgctaaca tcggaacgac cctcaccgct cagctggtgg
     8101 ccttcaagct gacctcgttc ggacccctgt tcattctgat cgggttcgtc tgggggttga
     8161 tcggcggacg ttacaagttc atcgggaaac cgctgttcta cttcgggctg gtgttcttcg
     8221 ggctggagct ggtgtcgaac tcgctcgatc cgataaggga ggacccggcc atcctatcgc
     8281 tgatctccaa cctggacaac ttcttcatcg ctctgttggt cggcgtggtc ttcaccaccg
     8341 ccgtgcagtc cagctcggtg acgtccgggc tcatggtggt gctggcgtcc agcggactgc
     8401 tcacgctgga acaggccatt cccgttctgc tcggggccaa catcggcagc accaccacca
     8461 cgctgttcgc ctcggccaag atggacctct gggcccgccg ggcggccatc gctcacctgt
     8521 tgttcaatgt ggccggggtg ctcatcttca ttcctttggc gggtttgctg gccacggtcg
     8581 tcaccgacct aaccccggac gtgggccagc aggtagcgaa cgcccacctc atattcaatg
     8641 tgatcaccgc gatcgtgttc ctggtgctgc tgaagcagtt cgagaaggta gtggtgagag
     8701 ttgtaccagg tgatgagaag gaagtgctct tccgccccag gttcctgacc aaggaaatgc
     8761 cggaggacaa tggtcaagcg ttccatctga tagagcaaga actcgggcac ggcctggagg
     8821 tcaccaagga cctgctggac gcttcattct cctcgctctc cgttaaggac aaacgggcca
     8881 agcaaaaggt gaccaagctg gaatcgctta acgactacct ggacgacgag atcgcggatg
     8941 ccatactcag gatgtcccgc cggtccctga agggggacga gggattgcgg accacgctgc
     9001 tggtgaggat gtccaacctg atggagcgac tgggcgatca cgccgaggac atcggggacc
     9061 tggccactgg cttccgggag aagggacggg cggtccccaa ggagcagctg gatcagctat
     9121 cggtcgtttt cgaaaagctg aggggcaacc tggaacttct cggcgaggat gttctgcagg
     9181 tgaacgaggg gaccaaggcc accataagga acgagacgtt gtccatgagc gcccgcataa
     9241 acgacatcta tagcgagcac ttggaaagga tgagggacgc cagcgtgccg tccgactcca
     9301 cactgctgga gctgctcacc atcatggaat cggccaacga gaaggtgcgg gagctggcgg
     9361 cgttagcatc ggattacgcc aagctcgctc cgcggaccgt cgaccgctga acgctcagac
     9421 gtacttttcc cggtatctca tcagctcctt ccagaacacc ggggtgaaca gcaccagcac
     9481 ggatatgaac tccagacgac cggcccacat ggtgaacgtt agtaccagct tcgccgcgtc
     9541 cggcaacccg ccgtacgaac cgtagggtcc gatactcccc aggccggggc cggcgttgga
     9601 cagcgtggcg atggccgcgc ttatggatgt cgtcggatcg atccccagca gtatgagcgc
     9661 caccaccgcc actatggccg tggcaaaata gcaaaggacc atggcgacga cggaggagag
     9721 cgcctcctgg ctgagcggcc tcccatcgat cttcacggtg aagatggaac ggggatgtat
     9781 ggtcttgtgc agggcagaag cgatgaattc cctggtgagg aagaaccggg cgaccttgat
     9841 tccgccggcg gtggaaccgg tgctgccccc tatgattatg agagcgagca gcaggaacac
     9901 caccgcctgg tcccagaaga tgtagttggc ggtggagaac ccggtggagg acatcaaaga
     9961 caccacctgg aacatcgagg ttcgcacacc ttgctcgatg tcggtgaact ccttgcccca
    10021 catgaaaacg gtgatgatcg ccgtggcggc cagaattatc ccgaggtaca aacggaactc
    10081 ggaattgcgg aagtaccgat tggggtcccg ggtcgttatc gcctggaaat gcagatagaa
    10141 gttggtactg gccaagaaca tgaagatgat gactatccac tcgacgttgg atgatgcgta
    10201 gtacgctatg ctatccgagt gtggtgagag acccccggtg cccatggtgg agaacatcac
    10261 gcagaaggag tcgaaaaccc cgatcccggt gaagagcagc agcaccaaca tcattaggga
    10321 caggaacccg tagatgtagt ggaacttacg tgcctcctcc tgaattcgag cggagaagtt
    10381 ctgcacgtcc aggccgggga actcgttctt gaagaggttt cggccgccca cccccagcat
    10441 cggcaggacg gtaacgaata tcatgatgat acccgcgccc cccagccagt gcgagaagct
    10501 tcgccagaac agtatgctct tgggccagga ctcgatgttc gtcattatgc tggagccggt
    10561 ggtggtgaag ccgctcatgg cctcgaacac ggcgtcgacc acgcccatgc cgtagagaac
    10621 gaacggaatg gcccccatta ccgtcaacgc cagccatccg gtggccacca cgaacatcgc
    10681 ttccgtggga cgggtgttct ccggcgagcg gtagcgcatc aatagcagga tgccgctgat
    10741 caggcacagc aagatgggga atatccaggg ccgggggtcc tcgccgtagt acagggcgac
    10801 cgcgtaaggg aacaccaggg ctatggccat gtagagcatc agcaccccga agatatgcgg
    10861 gatggcgctc tccttgcggg ccaccttgtc gaagatgctg ttcacgtcca cgttcaggcg
    10921 gtcgaagtaa taggccagtt ggccgaacca tcttcttgcc ttgttgtagg acgtggacat
    10981 gtgagctccc ctacggaccc accggtatgt tggccttgaa catccattcc agcttggcga
    11041 tggccgattg cagggcgtag atgaacacct tgtcgccctc ctcgatcacc gtatcgggag
    11101 aggggatcag cgccttgccg tccttgacca ccagggctat ggcggacatc ttgggcatat
    11161 cgatgtcggc tatcctcttt ccgatgatgc ggctgcccgc ggtgaccttc aggtcgaaga
    11221 actcctcgga gaacttctcc agcagcagca tcacctcgta gttgtgcacc gtctccttga
    11281 tgatctcgtt ggcgaccacg tgatagtagc cgacggaggc gtcgatgccg ctcataccga
    11341 agatctcctc gtattccctc ttggagtatc tggatatgac ctttgagacg cccaggtgct
//
LOCUS       DAOPZI010000042         9983 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_7925_length_9983_cov_10.218473, whole genome shotgun sequence.
ACCESSION   DAOPZI010000042 DAOPZI010000000
VERSION     DAOPZI010000042.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 9983)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9983)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9983
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_7925_length_9983_cov_10.218473"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            4..2733
                     /locus_tag="PKM11_07295"
     CDS             4..2733
                     /locus_tag="PKM11_07295"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HNX48343.1"
                     /translation="MLDPRILKVLEEKDIKEPTGAQSEAIPPVLAGENVLLVAPTGIG
                     KTEAAVLPLLHHLINTPGKGVRLLYITPLRALNRDMLKRLEEFGEALDLRVAVRHGDT
                     SQSERQRQSKFAPDILITTPETLQVMFTGKNLRAHLANVRYVVVDEIHELAGDERGAQ
                     LSIALERVVELAGDFQRVGLSATVGSHQEVANYLGGVGRKVRIVRAKVTKEMSISVQC
                     PEIVEQDKDLAGTLMSDPQLIACMRRAKALIEKHNSTLLFVNTRDTAEALAARYHIWD
                     EKFNVGVHHGSLSKETRVEMEDDFKNERLKGLICTSSLELGIDIGSSDFAIQYNSPRQ
                     VSRLVQRMGRAGHKIGRRSEGAIIASTPDEIAESLVVTRMALAERYEPLQVRQDPLTV
                     LANQLVAMASAGPVLVEKAYAIVRRSYPFRELSRQKFDTVLKQIAEIGLVFINGDEYR
                     RSGRGRKYFYENISMIPDERTYRIRDIGSRKIVGTLDESFVISFAEPFATFITRGRSW
                     RIVDIMDDELLVEQVKEIGSIPSWVGEDIPVPFEVAQEVGRMRRGYERAAYNGDATTY
                     KMLDEYLDEHRDKFPMPTDQRITLEVGKKLAILNMCFGSKVNETISKMLSVLLSARLG
                     ESVAVTTDPYRVIIDLPRDVAPSTIVDTLRSINASAVESLIRLVMKNSSHMRWRFVFV
                     AKKFGAVERDADYRNVSFARLVEAYENSSLMQETIDKVLWEDFDVRKTVQVVQDLESG
                     EIDIVVCGISPIGKAGLSQSKELITPQRADHSILMALKKRLEEESLHMSCLNCGTQWR
                     LKAREAGRFVVCHSCGGQMIAALNGYNRETIRLIKKKDLKEEEEKELRRLFKNASLVQ
                     SNGKKAMMTLSGRGIGADTAARILSSFGNNEDDLLRDILSAEITYARTKRFWD"
     gene            complement(2730..3356)
                     /locus_tag="PKM11_07300"
     CDS             complement(2730..3356)
                     /locus_tag="PKM11_07300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HNX48344.1"
                     /translation="MRCGKIVCIGQNYREHIREMRSDEPAEPVLFLKPPTALISDGEA
                     ILIPEGIGMVHHEVELALIVGKGGKDIAEKDALSHISHLAVFNDVTARDMQSAARKAG
                     LPWSLAKGMDTFAPLGKMVLRESVPDIHSLDLELRVNGETRQKGNTSQMIFAPERLIS
                     YISRFMTLEPGDVIATGTPSGVGALKPGDVVEAFVKGVGTLRNPVHTR"
     gene            complement(3359..3619)
                     /locus_tag="PKM11_07305"
     CDS             complement(3359..3619)
                     /locus_tag="PKM11_07305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48345.1"
                     /translation="MDMVEVMLTYIIIMFSSDGRRPSEIFDALHNMGFEPTTGNYDGV
                     YKWDKKATLDDAIYLADRVHLTLKGTGAVFKLETVAEANDKC"
     gene            complement(3635..4258)
                     /locus_tag="PKM11_07310"
     CDS             complement(3635..4258)
                     /locus_tag="PKM11_07310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RlmE family RNA methyltransferase"
                     /protein_id="HNX48346.1"
                     /translation="MSKNWLQQRRRDYYYRKAKQLDYRSRASFKLIQIHERFNLFKNG
                     MTVVDLGAAPGGWLQVAAERVGPKGKVIGVDLQPIEPIEGVQTIKGDIRKQEVMDELL
                     ALTGGKVDLVLSDMSPNITGSYSMDHARSIELCEMALSFALATLSPNGKMVFKMFEGD
                     LSRDLVAEVQKHFETVKRYSPEASRSSSSEIYVVAKGFGKGPKVQSG"
     gene            4349..5374
                     /gene="purM"
                     /locus_tag="PKM11_07315"
     CDS             4349..5374
                     /gene="purM"
                     /locus_tag="PKM11_07315"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HNX48347.1"
                     /translation="MQEKDWTYAKAGVDIDRKSQAISALVGHLKYRRTGRGSMIDLPG
                     QFTGLIDMGDHILTLATDGVGTKLLVAEALDKWDTVGIDCMAMNVNDTICVGAEPIAF
                     VDYIAIDEPNPKITEQIGKGLNAAAEMANVDLVGGEVAVLPEMVKGVDLSGTALGLLD
                     KRKMITGAEIEEGDVIIGLLSSGVHSNGMTLARKVLSSAGISLHDEVDGLDGSVGREL
                     LTPTYIYVRDVLKVVDAVKVTGMVDVTGGGLKNFVRLKKGFEYRITDPIEPQAIFRAI
                     QGIGGVTDHEMYKTFNMGMGYAIVLRPEGVEEVLSILKGKAQVVGKVVKGVGCGVPRL
                     KVHYDTY"
     gene            complement(5371..6036)
                     /locus_tag="PKM11_07320"
     CDS             complement(5371..6036)
                     /locus_tag="PKM11_07320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48348.1"
                     /translation="MDDIRLRSRVMLWSGLSFLIFLSSLIMIFWGGPVLELEGRRIGI
                     AQIIWLPGLIGSCSGLWLLLTLSGARGGISLSVALGNLAGAEALSLLLPVKEVSGMVW
                     ETGNGLVPATSFAALALTSLTWTAITLADPSRSTRTAYSVALAAVLAIGFLLSYNYLW
                     SLQGAMAVGLAAALFWGMAYDRRLHPYSKVKVKKQGSPWVVLLITFLGLPMLLLGLPY
                     LLL"
     gene            complement(6076..6627)
                     /locus_tag="PKM11_07325"
     CDS             complement(6076..6627)
                     /locus_tag="PKM11_07325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF531 family protein"
                     /protein_id="HNX48349.1"
                     /translation="MERRAGRATIAIFNSYDPRVFREAHRRILARAGPLALAYDFNLV
                     TLGFPFPEDLRLPTELADWVASSTSIGEDGSYLKELAAKGRFQGFPYPSKGLPPQLGL
                     PVLTTCDPEPQRKMEMREVAALLQNGQSVCLIFGAGPKGVPKEVRELAKHHLDVTFDG
                     RSLETCTALGAVAGALAHYLRGH"
     gene            complement(6632..7690)
                     /locus_tag="PKM11_07330"
     CDS             complement(6632..7690)
                     /locus_tag="PKM11_07330"
                     /inference="COORDINATES: protein motif:HMM:NF014027.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008612 - peptidyl-lysine modification to
                     peptidyl-hypusine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyhypusine synthase family protein"
                     /protein_id="HNX48350.1"
                     /translation="MVSKKDVLKEKVKQIDFDNIVTVKDLVEAYKDSSIQSRALATCA
                     IVYEKALKDKSRPTVILGLAGPLVAAGLRKVIADMIKFGMVDAIVTIGAIPYQDFYQA
                     RGYNHYKCSPRCDDLALREVFVDRIYDTLVDEDKFRETDALIGDIAEKLEPRGYGSRE
                     FMEILGKAIDDEDSILYNAAKYGVPIFVPALNDSSIGIGLTGLYYKKRMAKEPFMSID
                     SIRDNWELTQLKIKSEKTAVIYIGGGVPKNFIQQTEVICETLGHDKGGHHYAIQITQD
                     TPQWGGLSGCTFEEAQSWGKINRDANKSVAYVEASIGMSIMVGYILQSEVWKGRKRLK
                     YTWKDDMLTKVTKVPLGL"
     gene            complement(7738..7932)
                     /locus_tag="PKM11_07335"
     CDS             complement(7738..7932)
                     /locus_tag="PKM11_07335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48351.1"
                     /translation="MDWARGLSMEKRVHIKIDRNSDFTLREVLKKIEEIQTENPDLDV
                     FFDGDDYAICSRPRKVKSHV"
     gene            8293..9972
                     /locus_tag="PKM11_07340"
     CDS             8293..9972
                     /locus_tag="PKM11_07340"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HNX48352.1"
                     /translation="MDNRNPTAEQADVERLSKWLDGEGEGSTLLTWLGEGGDAVPEEE
                     LADLKERLARYEAELASVRGLLAVDGASETADGTVQRVQALIAERDRLLESHHREKDG
                     NDGNGLVEGQEKELLERYHAELKDKEEQWKRAGDDLSARSASLEKELAKIKIELKLKD
                     DELSVLRNGGGTISADLLSKLEVLQSKEREFLTLKNEADELRIRLKEKEDELDRIREA
                     ITYKEDELIRREEDLMYREKVYTAERHKLNEMKRETGGLEEAELMKKLEALKAEVASK
                     EDALRSKEKYVLAKQEELRMREQGLIEDEITYREKERALEITERKVKTGISRLDDLLL
                     GGMPIGSNIMIHGPPFIGKEVLANTFIMEGLRKGIPAIIVLTDKTPKDVRDEMRFIMS
                     GYEEYEKLGLVKYVDTYARAMGGDDNDPHTIYIERPNDHEKMAEAIESIARKFKEKHE
                     YYRLLFRSVSTLIAYSDPNSAFRFLSPLCGRRKKDDAVSIFIVEKGMHNEQELQMLGS
                     IMDGMVDFKVDQLKTFFAIKGISDVQSRAYIRYTATKSALTIGSFALDHIR"
BASE COUNT         2129 a         2896 c         3125 g         1833 t
ORIGIN      
        1 gaactgctgg acccccgcat cctcaaggtg ctggaggaaa aggacatcaa ggagccgacc
       61 ggggctcaga gcgaggcgat acccccggtg ctggccggag agaacgtgct ccttgttgcg
      121 ccgaccggca taggaaagac cgaggcggcg gtgctgcccc tcctgcacca cctgatcaac
      181 accccgggta agggcgtgcg cttgctgtac atcaccccgc tccgcgcgct caaccgagac
      241 atgctgaagc gcctggagga gttcggggag gctctggacc tgcgagtggc ggtgcgacac
      301 ggggacacct cccaatccga gcgacaacgc cagtccaagt tcgctccgga catcctgatc
      361 accacgccgg aaacgttgca ggtcatgttc accggcaaga acctgcgagc ccatttggcc
      421 aacgtgcgct acgtggtggt ggacgagata cacgagctgg ccggtgacga aagaggcgcg
      481 cagctatcca tcgccctgga gcgagtggtg gagctggccg gcgatttcca gcgcgtcggg
      541 ctatcggcca cggtcggctc gcaccaggag gtggccaact atctcggagg cgtcggccgc
      601 aaggtgcgca tcgtgcgggc caaggtgacc aaggagatga gcattagcgt gcaatgtccc
      661 gagatagtgg agcaggacaa ggacctggcc gggacattga tgagcgaccc gcagctcatc
      721 gcctgcatga ggcgggccaa ggccctcatc gagaagcaca attccaccct gctgttcgtc
      781 aacaccaggg acaccgcgga ggcgcttgcc gcccgatatc atatctggga cgagaagttc
      841 aacgtggggg tgcaccacgg ttcgctgagc aaggagacca gggtggagat ggaggacgac
      901 ttcaagaacg agcgtctgaa gggcctcata tgcacctcgt ccctggagct gggtatagat
      961 atcggctcgt cggacttcgc catccaatac aactcaccgc gccaggtttc ccgcctggtg
     1021 cagcgcatgg gccgggccgg gcacaagatc ggccgccgtt cggagggggc gataatcgcc
     1081 tccacgccgg atgagatcgc ggaaagcctg gtggtgacca ggatggccct ggccgagaga
     1141 tacgagcctc tgcaggtccg acaggacccc ctgacggtcc tggccaatca gctggtggcc
     1201 atggcctccg ccggaccggt gctggtggag aaggcttacg ccatcgttcg ccgctcctat
     1261 cccttccgag aactgagcag gcagaagttc gataccgtgc tcaagcagat cgcggagatc
     1321 ggactggtgt tcatcaacgg tgacgagtac cggcgctctg gacggggtcg gaagtacttc
     1381 tacgagaaca tatcgatgat cccggacgag cgaacgtacc gcataaggga catcggctct
     1441 cgaaagatag taggcacctt ggacgagagc ttcgtcatct ccttcgctga gccgttcgcc
     1501 accttcatca cccgcggtcg ttcctggcgc atcgtggaca tcatggacga cgagctcctg
     1561 gtggagcagg tcaaggagat cggctccatc ccatcctggg tgggagagga catcccggta
     1621 cctttcgagg tagcccagga agtgggacgc atgcgccgtg gctacgagag ggcggcgtat
     1681 aacggggacg ctaccaccta caagatgctg gacgagtatc ttgacgagca ccgggataag
     1741 ttccccatgc ccaccgacca gcgcatcacc ctggaagtgg gaaagaagct ggccatactc
     1801 aacatgtgct tcggcagcaa ggtgaacgag accatctcca agatgctgtc cgtgctcctc
     1861 tcggcccgac tgggggagag cgtggcggtg accaccgatc cctatcgggt gatcatcgac
     1921 ctgccaaggg acgtggcgcc gtccaccatc gtggataccc tgcgctccat aaacgcctcg
     1981 gccgtggaaa gcctgatccg cctggtgatg aagaactcca gccacatgcg atggcgcttc
     2041 gtgttcgtcg ccaagaagtt cggggcggtg gagagggacg ccgattatcg caacgtcagc
     2101 ttcgcccggt tggtggaagc gtacgagaac tcctcactga tgcaggagac catagacaag
     2161 gtgctgtggg aggatttcga cgtgcggaag accgtccagg tcgtccagga cctggagtcg
     2221 ggagagatcg acatcgtcgt ctgcgggatc tcgcccatcg gtaaggccgg actttcgcaa
     2281 tccaaggagc tcatcacccc gcagcgcgcc gaccactcca tactcatggc gctgaagaag
     2341 cgcttggaag aggaaagtct gcacatgtcc tgcctaaatt gcggcaccca atggagactt
     2401 aaggccaggg aggccggccg gttcgtggtc tgccacagct gcggcgggca gatgatcgcc
     2461 gccctcaacg gctacaaccg ggagaccatc cgcctgatca agaagaagga cctcaaggag
     2521 gaggaggaaa aggaactgcg ccggctgttc aagaacgcct cgctggtgca gagcaatggc
     2581 aagaaggcca tgatgaccct ttccgggcgg ggcattggcg cggacaccgc ggcgcgcatc
     2641 ctgtccagct tcggtaacaa cgaggacgat ctcctgcggg acatcctgag cgccgagatc
     2701 acctacgccc gaacgaaacg gttctgggat taacgcgtgt gcacgggatt gcgcagcgtc
     2761 cccacgcctt taacgaaggc ctcgaccacg tcgcccggct tgagcgcgcc gaccccgctg
     2821 ggggttccgg tcgctatgac atcgcccggt tcgagggtca tgaacctgga tatgtaagat
     2881 atcaatcgtt ccggcgcaaa gatcatctgg gaggtattgc ccttctgccg ggtctcgccg
     2941 ttcacccgca gctccaggtc cagggaatgg atgtccggca cgctttccct aaggaccatc
     3001 ttgcccaacg gcgcgaaggt gtccatgccc ttggccaggg accagggaag tccggccttg
     3061 cgcgccgccg actgcatatc acgggcggtc acgtcgttga agacggccag gtgggatatg
     3121 tgggataggg catccttctc cgcgatatcc ttgcccccct ttccgacgat cagggccagt
     3181 tcgacctcgt ggtgcaccat gccgatgccc tcgggaatta ggatcgcctc accgtccgag
     3241 atgagggccg tgggcggctt taggaacagc accggttcgg ccggttcgtc ggacctcatc
     3301 tcccggatgt gctcccggta gttctggccg atgcagacta tcttgccgca gcgcatggtc
     3361 agcacttgtc gttggcctcg gccacggtct ccagcttgaa caccgcgccg gtgcccttca
     3421 gggtgagatg cacgcggtcc gccagataga tggcgtcgtc cagggtggcc ttcttgtccc
     3481 acttgtacac cccatcgtag ttcccggtgg tgggctcgaa ccccatgttg tgcagggcat
     3541 cgaatatctc cgaaggacgg cgaccatcgg aactgaacat tatgatgatg taggtcagca
     3601 tcacctctac catgtccatg acggaataaa aagcttagcc gctctggacc ttggggcctt
     3661 tgccgaagcc cttggccacc acgtatatct cggagctgct ggagcgggac gcttccggcg
     3721 aataacgctt cacggtctcg aaatgcttct gcacctcggc gaccaggtcc cggctcaggt
     3781 ccccctcgaa catcttgaac accatcttgc cgttcgggga cagcgtcgcc agagcgaacg
     3841 agagcgccat ctcgcacagc tcgatggagc gggcgtggtc catggaatag ctcccggtga
     3901 tgttggggga catgtccgaa aggaccaggt ccacctttcc gccggtgagg gccaggagct
     3961 cgtccatcac ttcctgcttt cgtatatcgc cctttatcgt ttgcacgcct tcgatgggct
     4021 cgatgggctg caggtccacg ccgatcacct tgcctttggg gcctacgcgc tccgcggcca
     4081 cctgtagcca gccacccggc gccgccccca ggtcgaccac ggtcatgccg ttcttgaaga
     4141 gattgaagcg ctcatgtatc tgaatgagct tgaaggaggc tcggctgcgg tagtccagct
     4201 gcttcgcttt ccggtaataa tagtcgcgtc tgcgctgctg cagccagttc ttggacatgc
     4261 taatccgccc aatcccttgc aggataaaaa accattgccc gaccgatgat attttatcgg
     4321 caggggggat tcagctttgg gtaaggacat gcaagaaaaa gattggacct atgccaaggc
     4381 cggggtggac atcgatcgta aatcgcaggc catatcggcc ctggtaggcc atctgaagta
     4441 ccggcgcacc ggaaggggaa gcatgatcga ccttccgggg cagttcactg gcctcatcga
     4501 catgggggac cacatcctca ccctggccac ggacggggtg ggaacgaagc tgctggtggc
     4561 cgaggccctc gacaaatggg acacggtggg catcgactgc atggccatga acgtgaacga
     4621 caccatttgc gtcggcgcgg aaccgatcgc cttcgtcgat tacatagcta ttgacgaacc
     4681 gaaccccaag ataaccgagc agatcggcaa gggcctgaac gccgccgcgg agatggccaa
     4741 cgtagacctg gtgggcgggg aggtcgcggt gctgccggag atggtgaagg gagtggacct
     4801 ctcgggcacc gccctggggc ttctcgacaa gcggaagatg atcaccgggg cggagatcga
     4861 ggagggtgac gtcatcatcg ggcttctatc atcgggggtg cactctaacg gcatgaccct
     4921 ggcccgcaag gtgctgtcct cagccggtat ctccttgcac gacgaggtgg atggactgga
     4981 cggcagcgtc ggcagggagc ttctcacccc tacctacatc tacgttcgcg acgtgctcaa
     5041 ggtggtggac gcggtcaagg tcaccggcat ggtggacgtg accggcgggg gattgaagaa
     5101 cttcgtgcgt ttgaagaagg gcttcgagta ccgcataacc gaccccatag agccgcaggc
     5161 gatcttcaga gcgatacagg gcatcggcgg ggtcaccgat cacgagatgt acaagacctt
     5221 caacatggga atgggctacg ccatcgttct gaggccggaa ggggtcgagg aggtcctatc
     5281 cattctcaag ggcaaggcgc aggtggtcgg taaggtcgta aagggcgtcg gatgcggcgt
     5341 tccccggctc aaggttcact acgacaccta ttagagcagc agatagggaa gccccaacaa
     5401 cagcatgggc agccccagga aggttatgag cagcaccacc cagggcgagc cttgtttctt
     5461 gaccttcacc ttgctgtagg gatgcaggcg ccggtcatag gccattcccc agaacagcgc
     5521 cgccgccagg ccaacggcca tcgccccttg cagggaccac aggtagttgt aggagagcag
     5581 gaacccgatc gccaggaccg ccgccaaggc caccgaatag gcggtccggg tgctccggga
     5641 ggggtcggcg agggtgatgg ccgtccaagt tagcgaggtc agggccagag cggcgaagga
     5701 ggtggccggg accagcccat ttcccgtctc ccagaccatt ccggacacct cctttaccgg
     5761 aagaagcagc gataaggcct ccgcccctgc caggttccct agggctaccg aaagcgagat
     5821 gcctccgcgc gccccgctga gggtcagcag cagccataga ccggagcagg aaccgatgag
     5881 tcccggaagc cagatgatct gagcgatccc gatgcgcctt ccctccagct ccagcaccgg
     5941 ccctccccag aagatcatga tcaaagagga taggaagatt aggaaggaga gacccgacca
     6001 cagcatcacc cgagacctca gccggatatc gtccacgctg gagtaaagtt cctgaagcga
     6061 ctttaaactt gcctctcaat ggccgcggag atagtgagcg agcgccccgg ccaccgcccc
     6121 cagggccgtg caggtctcga gcgaacgacc gtcgaaggtc acgtcaagat gatgcttggc
     6181 cagctcgcgc acctctttgg gaacgccctt gggaccggcc ccgaagatca ggcagacgct
     6241 ctggccgttc tgaaggaggg cggccacctc ccgcatctcc atcttcctct gcggttcggg
     6301 atcgcatgtc gtcagcacgg gaaggcccag ctggggcggc agacccttgg atggataggg
     6361 aaagccctgg aagcggccct tggcggccag ttccttgagg taggagccgt cctcgccgat
     6421 ggaagtggag gatgccaccc agtccgccag ctcggtgggg agccggaggt cctccgggaa
     6481 agggaagccc agcgtgacca ggttgaagtc gtaggccaag gccagaggcc cggctctcgc
     6541 cagtatcctg cggtgcgcct cgcggaagac gcgggggtcg taggagttga atatggcgat
     6601 ggtggcccgg ccggcccttc gttccatcgg atcacagacc gagagggacc ttggtgacct
     6661 tggtcagcat atcgtccttc caggtgtact tcaaccgctt gcggcccttc cagacctcgg
     6721 actgcaggat gtagccgacc atgatcgaca tgccgatgga cgcctcgacg taggccaccg
     6781 atttgttggc atcgcggttg atcttccccc aggactgcgc ctcctcgaat gtgcagccgc
     6841 ttagaccgcc ccattgcggg gtgtcctggg ttatctggat ggcgtagtgg tgtccgccct
     6901 tgtcatggcc cagcgtctcg cagatgacct cggtctgctg gatgaagttc ttgggcactc
     6961 cgccacctat gtagatgacc gcggtcttct ccgacttgat cttcaactgg gtgagctccc
     7021 aattgtcacg gatggaatcg atgctcatga acggctcctt ggccatcctc ttcttgtaat
     7081 agaggccggt gagaccgatg ccgatggacg agtcgttcag cgcgggaacg aagatcggga
     7141 cgccgtactt ggcggcgttg tagagtatgg aatcctcgtc gtcaatggcc ttgcccagta
     7201 tctccatgaa ctcccggctt ccgtagcccc ggggctccag tttctcggcg atgtcgccga
     7261 tgagcgcgtc ggtctcccgg aacttgtcct cgtcgaccaa cgtgtcatag atgcggtcca
     7321 cgaacacctc gcggagggcc aggtcgtcgc agcgcggcga gcacttgtaa tggttgtacc
     7381 cccgggcctg atagaagtcc tggtagggaa tggcgccgat ggtcactatg gcgtccacca
     7441 tgccgaactt gatcatgtcg gcgatcacct ttcgcaggcc ggcggccacg agcggaccgg
     7501 caagacctaa gattaccgta ggacgggact tgtccttgag ggccttctcg taaactatgg
     7561 cgcaggtagc cagggcccgg ctctgtatgg acgagtcctt gtaggcctcg accaggtcct
     7621 tcacggtcac gatattgtca aagtcaatct gcttgacctt ttccttgaga acatccttct
     7681 tactaaccaa ttcaaaccct ctctgacatt tgaatctgaa gctatttcgg tcgggcctca
     7741 gacgtggctc ttgaccttcc tgggtcggct gcagatggcg taatcgtcac cgtcgaagaa
     7801 gacgtctagg tcggggttct ccgtttggat ctcctcgatc ttcttcaaga cctcgcgtag
     7861 cgtgaaatcg ctgttgcgat cgatcttgat gtgcaccctc ttttccatcg acagtcctct
     7921 ggcccagtcc aagctctttc ttagatgcaa ggctgaatat ataacttttt atcaacgaac
     7981 gcaatctgga aagcgctggc cagtcatcgc gttgcccgag gtcgcgggcg gctttggcgg
     8041 catgttcgcc tgagagccgt tcgattaata atatgtaaaa taaatatata ttataagctt
     8101 attcacatcc ggagaggaga gggcgtccca tctggtcttg ttgattgaac acgggacgaa
     8161 ggccactaaa ccattaaata tggtgctgga cagtgttata gggtcttcac tggatatcga
     8221 tctggtcaat ggacgttgaa tagaatggcc agagaaaagg cggtctcaga ggctcggacg
     8281 gagcaggctt cagtggataa taggaacccc accgccgaac aggctgacgt tgaacgccta
     8341 agcaagtggc tggacgggga aggagagggg tccaccctgc tgacatggct aggcgagggc
     8401 ggagatgcgg tccccgagga ggagctggcg gacctgaagg agcgccttgc ccgctacgag
     8461 gcggagctgg catcggtgag agggttgctg gcagtggatg gggccagcga gaccgcggat
     8521 ggaacggttc aaagggttca ggccctcatc gccgagaggg accggcttct ggaatcgcac
     8581 catagggaaa aggacggaaa cgatggcaac ggcctcgtgg agggtcagga aaaggagctg
     8641 ctggagcgct accatgccga acttaaggac aaggaagagc agtggaagcg cgccggggac
     8701 gacctttccg cacgtagcgc cagcctggag aaagagttgg ccaagatcaa gatcgaactt
     8761 aagctcaagg atgatgagct gtcggtctta cgcaacggcg gaggtacgat cagtgccgac
     8821 ctgctcagca aactggaggt actccagtcc aaggagaggg agttcctcac cctaaagaac
     8881 gaggcggacg aactgcgcat caggctcaag gagaaggagg atgagctgga ccgcatccga
     8941 gaggccatta cctacaagga ggacgaactc attcgccgcg aggaggacct gatgtaccgg
     9001 gagaaggtct ataccgcgga gaggcacaag ctaaatgaga tgaagcggga gaccggaggg
     9061 ctggaggagg ccgagctcat gaagaagctg gaggccctga aggccgaggt ggccagcaag
     9121 gaggacgcgc tccggtccaa ggagaagtac gtcctggcca agcaggagga gctgcgcatg
     9181 agggaacagg ggttgatcga ggacgagatc acctaccggg agaaggagcg cgccctcgag
     9241 ataaccgaac gcaaggtcaa gaccggcatc tcacgacttg acgacctgtt gctgggcggc
     9301 atgcccatcg gttcaaacat catgatccac ggcccgccgt tcatcggcaa ggaggtgctg
     9361 gcaaacacct tcatcatgga agggctgcgc aaaggcatcc cggccattat cgtcctgacg
     9421 gacaagaccc ccaaggatgt gcgcgacgag atgcgcttca tcatgtccgg atacgaggag
     9481 tatgagaagc tgggtctggt gaaatacgtg gacacctacg cccgagccat gggcggggac
     9541 gacaacgacc cgcatacgat atacatcgaa agacccaacg atcacgagaa gatggccgag
     9601 gccatcgaat ccatagccag gaagttcaag gagaaacatg agtactaccg gctgctgttc
     9661 cgttcggtat ctacgctgat cgcctattcc gaccccaact cggccttccg gttcctgagc
     9721 ccgctgtgcg ggcgccgcaa gaaggacgat gccgtctcca tcttcatcgt ggagaagggc
     9781 atgcacaacg aacaggaact gcagatgctg ggatccataa tggacggcat ggtggacttc
     9841 aaggtcgacc agctgaaaac attcttcgcc atcaagggca taagcgacgt gcagtcccgc
     9901 gcttacatca gatacactgc gaccaagagc gccctgacca tagggtcgtt cgccctggac
     9961 cacatccgct aggcgacctc tac
//
LOCUS       DAOPZI010000043         9620 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_8339_length_9620_cov_9.176895, whole genome shotgun sequence.
ACCESSION   DAOPZI010000043 DAOPZI010000000
VERSION     DAOPZI010000043.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 9620)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9620)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9620
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8339_length_9620_cov_9.176895"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..704)
                     /locus_tag="PKM11_07345"
     CDS             complement(<1..704)
                     /locus_tag="PKM11_07345"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48353.1"
                     /translation="MPRRVFGCCLVLLTALFLICISPAAMSAPGDVSVFQVSDTLTLD
                     AGKSVSFEWVAFNNGTDRLLVVPELRSDVPDRITWSLEPSYAVIEGGAGCSFYLNFSA
                     GTDMYTDVVPLDIVFKITDMSTSEYGEADHQIVLRAESLYGHLDRENRIMGVWENVLP
                     APFDGNWGAFGLSLAIWVMIGLIFMKVVGPTVHRLTRKTESKWDDVAIEVVRLPLAVL
                     IIAYGAISSLEILVLPP"
     gene            complement(747..1433)
                     /locus_tag="PKM11_07350"
     CDS             complement(747..1433)
                     /locus_tag="PKM11_07350"
                     /inference="COORDINATES: protein motif:HMM:NF001911.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HNX48354.1"
                     /translation="MRGVTEIEYLGHSAFVIRNSGKEVLIDPFLTDNPKAPPSASLVR
                     PDLILVTHAHHDHLGDALELSKRFSCPVLSVSEINDHLEEKGARVLQGNLGGEIELPF
                     CRVKLFPAFHSSSFEDGRYGGAACSFLVRMGDRTIFHAGDTALFNDMSLIADEADISV
                     ALLPVGGTYTMGVKDAVKAMRLLRARIMVPMHYDTWPSIAVDRSELVSAAPDHAFSVK
                     VLAPGERLVL"
     gene            complement(1430..2119)
                     /locus_tag="PKM11_07355"
     CDS             complement(1430..2119)
                     /locus_tag="PKM11_07355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HNX48355.1"
                     /translation="MNAEEALARLESMSDRSRLEGMSRYGIRVDHALGVSMPEMRNLA
                     KTIGKDHGLAMDLWRSGVHEARIMAGLLADPMQLTEDQMEEMVGDLHSWDVCDQCCSN
                     LFSRSPLGLRKALEWSARDAEFQKRAGFATMAALAVHRKELLEDDLLLLLEAVVRESH
                     DDRNFVRKAVNWALRQIGKRDLRMNALAISAAERIEAKGDRASRWVASDALRELRSEA
                     VQERLKSRQGK"
     gene            complement(2171..2509)
                     /locus_tag="PKM11_07360"
     CDS             complement(2171..2509)
                     /locus_tag="PKM11_07360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HNX48356.1"
                     /translation="MKKIEAIIRAETLDSVKCGLEKLGMNAMTITDVLGRGEQKGLEF
                     THRTGKYRVDLLPKIKIEVVIKDEDARKVIDTIIEKARTGEIGDGKIFVSPVEEVIKI
                     RTGESSKGKA"
     gene            complement(2515..3837)
                     /locus_tag="PKM11_07365"
     CDS             complement(2515..3837)
                     /locus_tag="PKM11_07365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HNX48357.1"
                     /translation="MKHRIGLKFALLLALALVALPLISNPVAAADGEVDSGDTAWLMI
                     STGLVFIMTPAVAFFYGGMLRKSNFLSMLGQSILIIGVVTIIWVLFGYSLTFGTDQGG
                     LIGDAEYLMLNGVDLVPNAIAPTVPHILFMMYQGMFAIITVALIIGGVAERMKLSSLI
                     VFLSIWTAAVYIPVAHWVWGGGWIYDLGALDFAGGTVVHITAGVSVLAAALVLGKRIN
                     QSRGGQEVPHNIPMVVLGGALLWIGWFGFNGGSALAANGLAANALVVTHISAAMAASV
                     WGLISWLDTGRVSVLGLISGGVAGLVAITPAAGFVNPTGALFIGLGAAVVCYGGILLR
                     KRLGFDDALDVWGVHGLGGTFGAIATGLFATTAVNAAGKDGLLYGGGADLLVAQTISV
                     IVVWAFAFGVTFVILKAISMVMPLRMTKDEEKIGADIIQHGESAYYLR"
     gene            complement(4037..4420)
                     /locus_tag="PKM11_07370"
     CDS             complement(4037..4420)
                     /locus_tag="PKM11_07370"
                     /inference="COORDINATES: protein motif:HMM:NF020434.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative zinc-binding protein"
                     /protein_id="HNX48358.1"
                     /translation="MPENEDCQCSGQELMIFSCSGGCNVGQLANAAAFRLATGGTGKM
                     ACLAAVSAGMPGPVTGAKQAKMVLAVDGCPVKCAAKTLEKVGIKPTHQVLITDLGLKK
                     VDDLRHSPEDVDRATRLCLDALPKK"
     gene            4518..5912
                     /locus_tag="PKM11_07375"
     CDS             4518..5912
                     /locus_tag="PKM11_07375"
                     /inference="COORDINATES: protein motif:HMM:NF019604.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HNX48359.1"
                     /translation="MKEYDLIVIGSGAGLNVVSKARRKGMKVALVENGPMGGTCLNRG
                     CIPSKILVTPAELVRVIADAKRMGIHAKVESTDFKMVRERMWSLISPDSEGILESIKN
                     DEGIDLYQTTAYFTGKNILQAGNEQITSQRIIIAVGTRTKVPEVPGLLDAGFYTTEDL
                     FEITELPKSMMIFGGGYKACELGMFLASFGCHTTIIGRNSRLLKNEEPEISEIVLRKS
                     REYMDVLVNTDVTEVRTENGLKVAVCRDRADGSVREVKAERILVATGVQSNADWLRPQ
                     TSGIALDKDNYIVVDKFLETNVPGIFAIGDIIGRTMFRHTANYHSELVWYNMFGGKRV
                     ELDEHAVPHAVFGYPEVGSVGLTQEECKKLGYKVLIGYSEYMDCAKGYAMAEEEGLVK
                     VIVDQGSRRILGAHIVGSHAAILVQQIVYLMNAGDQTYLPLGRSQCIHPALSEAVVRA
                     FGALEDPEHEHHHH"
     gene            complement(5906..6832)
                     /locus_tag="PKM11_07380"
     CDS             complement(5906..6832)
                     /locus_tag="PKM11_07380"
                     /inference="COORDINATES: protein motif:HMM:NF014826.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HNX48360.1"
                     /translation="MCCVVQSSVLSKADVHVHTRYSGFGQYKAITFPESICRPEVVVD
                     EARKKGISVLCITDHNSILGALRAREYAKQFSDIEVVVGEEIGTEEGEIIGLFLKEGI
                     PKGLPIRETIRRIREQGGLVIAPHPFSAHVPALGRLVDKLDIDGLEILNGGHVDGYAN
                     EAAKNYAANGKWAVLGGSDAHASAQIGCCYTTFVGRTAEEFRTAILEKRTATAGEVST
                     LQMGIKWTVQVVLKTDILIIQSLFGPLKMEHPDDPLLNKINVMRGENKLAALISSSIF
                     LIPPIPIVTSVTGVKLMQRLNRIYSFSGPDRQ"
     gene            complement(6883..7002)
                     /locus_tag="PKM11_07385"
     CDS             complement(6883..7002)
                     /locus_tag="PKM11_07385"
                     /inference="COORDINATES: protein motif:HMM:NF018140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin FeS4 iron-binding
                     domain-containing protein"
                     /protein_id="HNX48361.1"
                     /translation="MTNVGEVYECEICGNKVEVKEAGGGTLVCCGQDMNKVRG"
     gene            complement(7032..8204)
                     /locus_tag="PKM11_07390"
     CDS             complement(7032..8204)
                     /locus_tag="PKM11_07390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HNX48362.1"
                     /translation="MQAVEIAEGIYWVGALDWNGRNFHGFATLRGTSYNAYLILDEKN
                     VLIDGVKTPFLGEMMARVRSVIDPKEIDIIVSNHAEGDHASGLPMIQHLTGAEILSSK
                     KGVDALRANYGDMRIREVKDGEELSIGKRTLRFIETPMVHWPESMFTYLKEDQILFSM
                     DAFGQHYCSSERFDDQVDLGVLMEEAATYYANIVMPFGNQVKKAYEKVKDLPLRMLAT
                     SHGLIWRTHLKEIVDAYVGWAEGVAEDRVLVIYDTMWGSTGRMAEAIAEGVSSQDIPV
                     VVMRLTDTDRSMVMREVLRSKVIVVGSCTMNNGMFPTVADVTTYIKGLRPKGRKAAVF
                     GSYGWGGGSSKAIRENLSAGGLELPYPDLDMKFAPMKEGAEKCFAYGVDIAKSIKN"
     gene            8284..8517
                     /locus_tag="PKM11_07395"
     CDS             8284..8517
                     /locus_tag="PKM11_07395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48363.1"
                     /translation="MHEVLRLVVEALSDVMGEKRYTTREMEDLLFTFYAYRCPDDLSR
                     SLNKLRLMGVLCGEVDREQACWVWWLPKKDQPE"
     gene            complement(8505..>9620)
                     /locus_tag="PKM11_07400"
     CDS             complement(8505..>9620)
                     /locus_tag="PKM11_07400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis/translation initiation
                     ATPase RLI"
                     /protein_id="HNX48364.1"
                     /translation="VAIAATIMKDADIYFFDEPSSYLDIYQRLRVARIIESLSKEKQV
                     IVIEHDLAILDFLADNVYLVFGSEGAYGIYSQPRQVRQAINVYLDGYAKEENMRFRDT
                     QIVFESRPPRANWEQFDLLEYGTIECQYPSFHLKVEPGAIKIGETVGVVGPNAIGKTT
                     FVKVLAGVQQPTVGKIDTSFRVSYKPQYISPDFDGTVREMFDATVKDFFESGFFQSEI
                     ARPLSLKNLLEKNVMNLSGGELQRVAIASCLSREADIYLLDEPSAYLDSNQRMEAAKT
                     VRRVMEKRGRSAMVVDHDIYFLDMVSDSIMVFSGTAGKEGLGQGPLDMRNGMNTFLAD
                     VDVTFRRDNDTNRPRINKPGSRLDREQKERGEYYYSG"
BASE COUNT         2000 a         2904 c         2703 g         2013 t
ORIGIN      
        1 gggggtagca caagtatctc cagcgaagat atcgcgccgt aggcgatgat gagcacggcg
       61 agcggcagcc tgaccacctc gatggcgacg tcgtcccact tgctctccgt cttgcgcgtc
      121 aggcggtgaa cggtcggacc gactaccttc atgaagatca aaccgatcat cacccagatc
      181 gcaaggctca gtccgaaagc gccccagttg ccgtcgaaag gcgcggggag gacgttctcc
      241 cacactccca tgatccggtt ctcccggtcc aggtgtccgt acagggactc ggccctcagg
      301 acgatctgat ggtccgcctc tccgtattcc gaggtgctca tgtcagtaat tttgaaaact
      361 atgtctaacg gcaccacgtc cgtgtacatg tcggtgcctg ccgagaagtt caggtagaaa
      421 ctgcatcctg cgcctccttc gatcaccgcg tagctcggct ccaggctcca ggtgatgcgg
      481 tccgggacgt cagagcgcag ctcgggtacg accagtaaac ggtcagttcc gttattgaag
      541 gcgacccatt cgaacgaaac gctcttacca gcatccaatg ttagggtgtc gctgacctgg
      601 aataccgata cgtctccggg agcggacatg gcggccgggc tgatgcatat caagaacagt
      661 gccgtgagca gcaccagaca gcaaccgaaa acccttctag gcatggccga aacccttcat
      721 gtcccttgag aataaaactt tttacctcag aggaccaggc gttcccctgg tgccagcacc
      781 ttcacggaga acgcatggtc aggggcggcc gacaccaatt cggaacgatc aacggcgatg
      841 ctcggccagg tatcgtaatg catggggacc atgatgcgtg ctcgcaggag gcgcatagcc
      901 ttcaccgcat cctttactcc catggtgtag gttccgccca ccggaagcaa agctacggaa
      961 atgtcagctt catcggcgat caaggacata tcattgaaca gagcggtgtc accagcatgg
     1021 aaaatcgtcc tatctcccat gcgaacgagg aaggagcagg cagcgcctcc gtaacggccg
     1081 tcctcgaagg acgaggagtg aaaggccgga aataatttaa ctcggcagaa gggcagctcg
     1141 atctctccgc ctaagttacc ctgtagcacc ctggctccct tttcctccag atggtcgttg
     1201 atctcggata cggagagcac cggacagctg aaacgtttgg atagttccaa cgcatctccc
     1261 agatggtcat gatgagcgtg ggtcaccagg atgaggtctg gtctgacaag ggatgccgat
     1321 ggcggggcct tggggttgtc cgtcaggaag ggatctatga gcacctcttt ccctgagttc
     1381 ctgatgacga aggccgagtg gcctaggtat tctatctctg tcacgcccct catttccctt
     1441 gcctgctctt caacctttcc tggaccgcct cgctgcgcag ctcccgcagg gcgtcagagg
     1501 ccacccacct ggaggcccgg tcacccttgg cctcgatcct ctcggcggcg ctgatggcca
     1561 gggcgttcat ccgcaggtcc cgcttaccga tctgccgcaa ggcccagttc actgccttgc
     1621 gcacgaagtt gcggtcgtcg tggctctccc ggaccaccgc ttccaggaga agtaggagat
     1681 catcttcaag cagttccttc cggtgcacgg ccagggcggc catggtggcg aagcccgccc
     1741 tcttctggaa ctccgcatcc cgtgcggacc attccaacgc cttccgcagg cctagcgggg
     1801 agcggctgaa gagattggaa cagcactggt cgcagacgtc ccaggaatga aggtccccga
     1861 ccatctcctc catctggtcc tcggtgagct gcatcgggtc agctagaaga ccggccatta
     1921 tgcgcgcctc gtgcacccct gagcgccaga ggtccatggc caatccgtgg tccttgccaa
     1981 tggtcttggc caaattccgc atctcaggca tgctgacgcc cagagcgtgg tcgaccctaa
     2041 ttccgtatct ggacatccct tccaaccggc ttcgatcgga catcgactcc agtcgggcaa
     2101 gggcctcttc ggcgttcatt gaaaatgaag aaggattaaa aagataaaaa ggggaggtcc
     2161 tgagagagta tcaggccttc cccttgctgc tctcgccggt cctgatcttg atcacctcct
     2221 ccaccgggga cacgaatatc ttcccgtccc cgatctcccc ggtcctggcc ttttcgatta
     2281 tcgtatcgat cactttcctg gcgtcctcgt ccttgatcac gacctcgatc ttgatcttgg
     2341 gaagcaggtc cacccggtac ttaccggtgc gatgggtgaa ctccaatcct ttctgctctc
     2401 ccctgccaag cacgtccgtg atggtcatgg cgttcattcc cagcttctcg aggccacact
     2461 tcaccgagtc cagggtctcg gcgcggatta tcgcttcgat cttcttcatg atgttcacct
     2521 cagatagtag gcgctctcgc cgtgctggat gatgtcggcg cctatcttct cctcatcctt
     2581 ggtcatgcgc aggggcatca ccatcgagat tgctttcagt atcacgaagg tcacgccgaa
     2641 agcgaaggcc catacgacga tcaccgagat cgtctgagcg accagcaggt cagcccctcc
     2701 gccgtacagc aacccatcct ttcccgccgc gttcaccgca gtggtggcga atagtccggt
     2761 ggcgatggct ccgaaggtac cgcccagtcc gtgtaccccc cagacatcca gggcgtcatc
     2821 gaaccctaaa cgctttcgaa gcagaatgcc gccgtaacat accaccgccg ctcccagtcc
     2881 gatgaacagg gcgccggtag gattgacgaa tcccgccgct ggagttatgg ccaccaggcc
     2941 ggccactccg ccggatatca ggcccagcac gctcacccgt ccggtgtcga gccagctgat
     3001 caatccccat accgacgcag ccatcgcggc cgagatgtga gtcacgacca gcgcgttcgc
     3061 ggccagtccg ttcgcggcca gggcgctgcc gccgttgaat ccgaaccacc ctatccagag
     3121 cagagcgccg cccagcacca ccattggtat gttgtgcgga acctcctgac ctccccggga
     3181 ctgattgatg cgctttccca ggacgagagc ggccgccagc acagaaaccc cggcggttat
     3241 gtgcaccacc gttcctccgg cgaagtccaa cgctccaagg tcgtatatcc atcccccgcc
     3301 ccagacccaa tgggccaccg ggatgtatac cgccgcggtc cagatggaaa ggaacacgat
     3361 gagcgaactg agcttcatgc gttcggccac gccaccgatg atcaaggcga cggttatgat
     3421 ggcgaacata ccctggtaca tcatgaacag tatgtggggt accgtgggcg caatggcgtt
     3481 gggcacgagg tccactccgt tcaacatcag gtattcggcg tctcctatca gtccaccttg
     3541 gtcagtgccg aaggtgagcg agtaaccgaa caacacccag atgatggtca ccaccccgat
     3601 gatcaatatg ctttgtccaa gcatggacag gaagttgctc ttgcgcagca tacccccgta
     3661 gaagaaggcc accgccgggg tcattatgaa gaccaggccg gtggagatca tcagccatgc
     3721 ggtgtccccg ctgtccactt ccccgtccgc cgccgccacc gggttggaga tcaggggtag
     3781 cgccaccagg gccaaggcca agagcaacgc gaacttcaag ccgatcctat gtttcatcat
     3841 ttgcatcctc ttcgctctct tagaccgaca taacatcggt catttcgtca gtttgataga
     3901 taattaacta ataaaacatt tctatactaa tcaaatgagt aggtttacaa ttgaaaagtg
     3961 tataaatgta caattagaat cataaaattc tatatggaat caaaaagtaa aaaaaagtta
     4021 atgggttaag ggaacatcac ttcttgggga gagcgtccag gcataaccgg gtcgcccggt
     4081 ccacgtcctc cggggaatgg cggagatcat ccaccttctt caggcccagg tcggtgatca
     4141 ggacctgatg ggtcggtttg atacccactt tctccagggt cttggccgcg cactttaccg
     4201 ggcatccgtc cacggccagt accatcttgg cctgctttgc tccggtgacc ggtccgggca
     4261 ttccggccga aacggccgcc aggcaggcca tcttacccgt tccgccggtg gccaaacgga
     4321 aagcggcggc gttagctagc tgtcccacgt tacatcctcc ggagcaggag aagatcatca
     4381 gttcctgacc gctacattgg caatcctcgt tctcgggcat tttcctcagc atcgaatcgc
     4441 agttccggga agataatcgt tccgcttctg gaacactatt ttaaatcagc atctccctag
     4501 gtgagagtgg gttctgcatg aaggagtacg acctgatagt catcggttcc ggcgcggggt
     4561 tgaacgtggt gtccaaggcc aggcgtaagg gcatgaaggt cgccttggtg gagaacgggc
     4621 ctatgggcgg aacctgtctc aatcgaggtt gcatccccag caagatactg gtgacgccag
     4681 ccgagctggt gagggtcatc gccgacgcca agcgcatggg cattcacgcc aaggtggaga
     4741 gcaccgattt caagatggta agagagagga tgtggagcct catctctcct gacagcgagg
     4801 gtatactgga gagcatcaag aacgacgagg ggatcgacct ctatcagaca acggcatact
     4861 tcaccgggaa gaacatcttg caggccggga acgagcagat cacctctcag aggataataa
     4921 tcgccgttgg aaccaggacc aaggtccctg aggtgcccgg acttctcgat gccgggttct
     4981 acaccaccga ggacctcttc gagatcaccg agcttccgaa gagcatgatg atcttcgggg
     5041 gaggctacaa ggcctgcgag ctaggaatgt tcctcgcttc gttcggatgc cacaccacca
     5101 tcatcgggcg gaactcccgt ttgttaaaga acgaggagcc ggagatcagc gagatcgtac
     5161 tgcggaaatc aagggagtac atggacgtgc tggtgaatac tgacgtgacc gaggtgcgca
     5221 ccgagaacgg gctgaaggtg gcggtctgcc gggaccgtgc ggacggcagc gtccgggagg
     5281 tcaaggccga aaggatactg gtggccaccg gggtgcagag caacgccgac tggcttcgcc
     5341 cgcagacctc cgggatcgcc ctggacaagg acaactacat cgtggtggac aagttcctgg
     5401 agaccaacgt ccctgggata ttcgccatcg gggacatcat aggccgcacc atgttccggc
     5461 acaccgccaa ctatcactcc gagctggtat ggtacaacat gttcggaggg aagcgggtgg
     5521 agctggacga gcatgcggta ccgcatgccg tgttcggtta tccggaagtg ggaagcgtcg
     5581 gtctcaccca ggaggagtgc aagaagctgg ggtacaaggt gcttatcggc tacagcgagt
     5641 acatggactg cgccaaaggg tacgccatgg ccgaggagga ggggttggtc aaggtcatcg
     5701 tcgatcaggg aagccgccgc atactggggg cgcacatcgt cggttcgcac gccgcgatac
     5761 tggtccagca aatagtctat cttatgaacg ctggcgatca aacatatctt ccgttgggac
     5821 gcagccaatg catacacccc gccctcagcg aagcggtggt cagggccttc ggggcgctag
     5881 aggacccgga gcatgaacat catcatcact gacggtcagg tcccgaaaaa ctgtagatgc
     5941 ggttgagcct ctgcatgagc ttaaccccgg tcacgctggt gacgatcggt atcgggggta
     6001 tcaggaatat cgacgatgag atgagcgcgg caagcttgtt ctccccacgc atgacgttga
     6061 tcttgttaag cagggggtcg tcagggtgtt ccatcttcaa aggtccgaag agggactgaa
     6121 ttatgagtat gtcggtcttc agcaccacct gcacggtcca cttgatgccc atctggaggg
     6181 tggagacctc tcctgccgta gccgttctct tttccaggat ggccgttcga aattcctccg
     6241 ctgtccgccc cacgaaggtg gtgtagcagc agcctatctg tgccgaggca tgggcgtcgc
     6301 ttccgcccag caccgcccac tttccgttgg cggcatagtt cttggccgcc tcgttggcgt
     6361 agccgtccac atgaccgccg ttcagtatct ccagaccatc gatgtccagt ttgtccacga
     6421 gtctgcccag ggctggcacg tgggcgctga agggatgcgg cgcgatgacc agtccgccct
     6481 gctcccttat ccttcgtatg gtctcccgta tcggcagacc cttggggatc ccttccttga
     6541 ggaacaggcc gattatctcc ccttcctcgg tgccgatctc ctctcccacc actacctcga
     6601 tgtcggagaa ctgcttggcg tactcgcgcg cccgcaacgc ccccagtatg gaattgtggt
     6661 cggtgatgca taggacactg atgcccttct tacgtgcttc gtcgaccacc acctccgggc
     6721 ggcaaatcga ttccggaaag gtgatggcct tgtattggcc aaaaccggaa taacgggtgt
     6781 ggacatgcac atcggccttg ctgagcacgg aagattgaac cacacaacac atttaattag
     6841 tttcgcaccc agcataaaaa agatatgaga gggggtcgcg gctcagcccc tgaccttgtt
     6901 catgtcctga ccgcagcaca ccaaggtgcc gccgccggcc tccttgacct ctaccttgtt
     6961 cccgcagatc tcgcactcgt aaacctcgcc aacgttggtc atttattaca cctgtcccga
     7021 aaacgcaacc ttcagttctt aatgcttttc gcgatgtcca caccgtaggc gaagcatttc
     7081 tcggcccctt ccttcatcgg ggcgaacttc atgtccaggt ccggataggg gagctccagt
     7141 ccgccggccg acaggttctc gcggatggcc ttgctggacc ctccgcccca gccatagctg
     7201 ccgaagacgg cggccttccg tcccttaggt ctcagccctt tgatgtaagt ggtcacatca
     7261 gcgaccgtgg gaaacatccc gttgttcatg gtgcacgagc cgaccacgat taccttggag
     7321 cgcaggacct cgcgcatgac catggagcgg tcggtgtccg tcagtcgcat gaccaccacc
     7381 gggatgtcct gcgagctcac gccttcggcg atggcctcgg ccatgcgtcc ggtggaaccc
     7441 cacatggtgt cgtagatgac gaggacccgg tcctccgcca cgccctcggc ccagccgacg
     7501 tacgcatcca ctatctcctt gaggtgggtg cgccagatca acccgtgcga ggtggccagc
     7561 attctcagcg gcaggtcctt caccttctca taggccttct tgacctggtt cccgaagggc
     7621 atgacgatgt tagcatagta cgtcgccgcc tcctccatca gaacgcccag gtccacctgg
     7681 tcatcgaagc gctccgagct gcagtaatgc tgcccgaagg cgtccatgct gaacagtatc
     7741 tgatcttcct tgaggtaggt gaacatcgat tccggccaat gcaccatcgg ggtctcgatg
     7801 aagcgcaggg tgcgctttcc gatcgagagc tcctcgccgt ccttgacctc ccttatcctc
     7861 atatccccgt agttggcgcg cagagcatcc acgcccttct tcgaggacaa tatctccgcc
     7921 ccggtgaggt gctggatcat aggaagtccg ctggcgtggt ctccctccgc gtggttggaa
     7981 acgatgatat cgatctcctt cggatcgatg accgagcgaa cgcgggccat catctctccc
     8041 aggaaagggg tcttcacacc gtcgatgagc acgttcttct cgtcaaggat aaggtaagcg
     8101 ttgtaggacg tgcctcgcag ggtggcgaaa ccgtgaaagt tccgaccgtt ccaatccaag
     8161 gcgccgaccc agtatattcc ttccgcgatc tccaccgctt gcatagtaga ccaccaacga
     8221 tgccgaggtg atttaaacat tgtcggcaaa gctttttgtg ccggtccgac cgatgaccgg
     8281 acgatgcatg aggtcctgcg gctggtggtg gaagcgctca gcgacgtgat gggcgagaaa
     8341 cgttacacga ccagggagat ggaggacctt ctcttcacct tctacgccta tcgttgtcct
     8401 gacgatcttt cccgttcgct caacaaactg aggctcatgg gcgtgctatg cggcgaggtc
     8461 gatcgggagc aggcctgctg ggtgtggtgg ctgccgaaga aggatcagcc cgaataatag
     8521 tactctccgc gttccttctg ctcccggtcc aaccgtgaac cgggcttgtt tatacgcgga
     8581 cggttggtgt cgttgtccct tctgaaggta acgtccacat cggcgaggaa ggtgttcatc
     8641 ccatttcgca tgtccaaggg gccctggccc aacccctcct tgccggccgt accgctgaag
     8701 accattatgg agtcggatac catgtccagg aagtagatgt cgtgatcgac gaccatggcg
     8761 ctgcgtcccc tcttctccat gacccttcgg acggtcttgg cggcctccat gcgctggttc
     8821 gagtccaagt acgccgaagg ctcgtcaagc aggtagatgt ccgcctcgcg ggaaaggcag
     8881 gaggcgatgg cgactcgctg cagctcccct ccagaaaggt tcatcacgtt cttctccaag
     8941 aggttcttca aggacaacgg gcgagcgatc tcgctctgaa agaagccgga ctcgaagaag
     9001 tccttcaccg tggcatcgaa catctctctg accgtgccgt caaaatcagg gctgatgtac
     9061 tgcggcttgt agctgaccct gaagctggtg tctatcttac caacggtagg ctgctgaact
     9121 cccgccagca ccttcacgaa ggtcgtcttt ccgatggcgt tcggacctac cacgcccacg
     9181 gtctccccga tctttatggc acccggttcg accttgagat ggaaggacgg gtattggcac
     9241 tcgatcgttc catattccag gaggtcgaac tgctcccagt tggcccgcgg cggccgggac
     9301 tcgaacacta tctgggtgtc ccggaagcgc atgttctcct ccttggcgta gccgtccagg
     9361 tagacgttga tggcctgacg gacctgcctc ggctgggaat atatgccgta ggctccctcg
     9421 gaaccgaaga ccaggtagac gttgtccgcc aaaaagtcga gaatggccag gtcgtgctcg
     9481 atgacgatca cctgtttctc cttggacagg ctctcgatga tccgggcgac cctcagtctc
     9541 tggtagatat caaggtatga ggacggctcg tcaaagaagt agatgtcggc gtccttcatg
     9601 atggtggccg cgatggccac
//
LOCUS       DAOPZI010000044         9175 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_8908_length_9175_cov_9.889693, whole genome shotgun sequence.
ACCESSION   DAOPZI010000044 DAOPZI010000000
VERSION     DAOPZI010000044.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 9175)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 9175)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9175
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_8908_length_9175_cov_9.889693"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..213
                     /locus_tag="PKM11_07405"
     CDS             <1..213
                     /locus_tag="PKM11_07405"
                     /inference="COORDINATES: protein motif:HMM:NF020334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48365.1"
                     /translation="IMVNDACASVSIHDIYHDNHPLIKTHVHNHLGNHKCMNMMVLSG
                     EAAQINELLDQMYRLEGIAYLKFIRS"
     gene            complement(200..1570)
                     /locus_tag="PKM11_07410"
     CDS             complement(200..1570)
                     /locus_tag="PKM11_07410"
                     /inference="COORDINATES: protein motif:HMM:NF012955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HNX48366.1"
                     /translation="MFLKRVRSEGLAHISYYLESNEEAAVIDPRRDVDDYLTLARERG
                     ARVVLVLETHRNEDYVSGALELANATGAAIYHGDQLEFGYGNPLEDGQEFRLGDLIIR
                     AMHTPGHTYESHCYLVSDDRGPFLLFSGDTLFSGDVGRTDLTGPESTRDLSEMLYRSL
                     HERIVPLGPEIMVLPAHGAGSACGHDISEREMTTIGLEVRDNHALSMSKLDFMMAKMG
                     EGMERPPYFSRMEALNLNGPIIFGTLPQPPPLPPKKVMEAQEGGALVLDVREPHNFAA
                     AHVPGALNVWLNGLPIYGGYAIPYGRPLIIVAERQQQVDLAVRYLIRIGYEDIIGHLG
                     HGMESWIKGGNATSTIAASTVHEIRRRQLAGEDMLLVDLRDRRELGSGAIPGAMLLHL
                     GRLMERSSELPRDREMVLFCGSGYRGGIAASLLRNSGITNVRIMLGGLGSWKANGYPV
                     EKLRNV"
     gene            complement(1612..1959)
                     /locus_tag="PKM11_07415"
     CDS             complement(1612..1959)
                     /locus_tag="PKM11_07415"
                     /inference="COORDINATES: protein motif:HMM:NF025210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HNX48367.1"
                     /translation="MPKFWSDRPPLYVHRLQRNNEFRGERFATVDEGDETTVISPEAG
                     PEANGPYACMTMGPFDLSTVGILARASDALAEAGIPIFVISTFRYDHLLVPLDRKDEA
                     VQALIEEGFERTG"
     gene            2229..3497
                     /locus_tag="PKM11_07420"
     CDS             2229..3497
                     /locus_tag="PKM11_07420"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="HNX48368.1"
                     /translation="MGSASHHGVRPEEAERRLRTKEGQGDKVSLGDRLRVLMLKGDLK
                     RKLLAIVILGLLIYGLVIALDGLLIRPLLGDVLSDPTDLDFYRARASNILEGKVPYVD
                     FTSESPPLIMYLFTIPQLTGGSVQAYQLFFTAFAILTSATFFLLLRRYDERKAMAASI
                     LYLVYPLGMMEFGFGVQDESITIFLFVLPLLLLLHQRAAASGAASFLGVLTKMFNVIV
                     LPWTFLHSDNKGRLNMVLAFGFLALVVILPFMLLYPGDLPSFTYYFLGHPETPTGGSS
                     ISPWHYLGELGFGLPGWAGVALTLVGLGAASLYAYWKKLSLWQGATLVTMVFFLTYPK
                     ILLVYFMMPGVLLLMWGVEDRKVVLKLTAMLVPLFLSVAITGNGKVPMMDGPGVWLIG
                     IVLSLVGWALFVHAWWKVKDERPFFERAEG"
     gene            complement(3498..3857)
                     /locus_tag="PKM11_07425"
     CDS             complement(3498..3857)
                     /locus_tag="PKM11_07425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HNX48369.1"
                     /translation="MPEDVPAAGKARDPAWAMLVIAGLLEPVWVTAMKLSEGFTVIPW
                     AAATFIVLFFSMYLLGRSLKMNIPMGTAYAVWVGIGAIGALIVGILLFNEPSDLLRLF
                     FVLLIVVGIVGVQVTSK"
     gene            complement(3859..4191)
                     /locus_tag="PKM11_07430"
     CDS             complement(3859..4191)
                     /locus_tag="PKM11_07430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HNX48370.1"
                     /translation="MISLAWVFLVIAGFMEPCWVIGLKKSEGFKRLGWSAFTVVFIFA
                     SMYFLALAIDMDLPMGTAYAVWTGIGAVGALIAGIMLFKERAELVRMFFILLIVIGIA
                     GVQMTAGV"
     gene            4386..5105
                     /locus_tag="PKM11_07435"
     CDS             4386..5105
                     /locus_tag="PKM11_07435"
                     /inference="COORDINATES: protein motif:HMM:NF012235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX48371.1"
                     /translation="MDGISLTVYPGETFGLLGPNGSGKTTTIRMLNGIIRPSAGKAFV
                     NGFDISTQIDDVKRSTGLLAESPGLYEKLSPREYLEFVGSLYDVERSLLKDRADRLLE
                     LFDLKQRGDDLMEGFSRGMKQKVLIAAALIHDPPIVFLDEPTSALDPLASLVVRDLIK
                     DLAEKAGKTVFVSSHILPLMEEVCDRIAIIDHGKVAAAGTVTEILEQSGTFTLEDAFI
                     KLTGGAGRPDALSWRKAVAKA"
     gene            5092..6654
                     /locus_tag="PKM11_07440"
     CDS             5092..6654
                     /locus_tag="PKM11_07440"
                     /inference="COORDINATES: protein motif:HMM:NF024110.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX48372.1"
                     /translation="MPKPKWWLIARNEYLLKTSGIRRWRRLFPLALVALLAWYVVFAA
                     PAVFSLASDLTKDLLLSEAALSFMQVMLFVIFISVFTVPIIQTLQDTNLAPLETLLSA
                     PVRPADVLLGKFLGMLPTYSILITVLAGTFLALFIPFGMTLDQVLLSILVFILVVLIS
                     LWLGLLTAAMLKARLNRSQKGREAGQALALIIALPLVGLMYLSMNGEMMGALQGKGAS
                     LSDAFWLLPSSWGADLVLRFLQHPGDLGYEAGSTALGLLGLSGTLVLSLIAGVRLSGR
                     AYDLEPVSFATPRAAPEGHLYAYARALAGNKHLGTVLVTVMKDYGRRLENLSRIIYIL
                     GLVVMMEVFMLGSLPPGNYVTLALLTASWLMAFLCVFVVGEVTARGKDNLFIYRKAPR
                     GETRLVLARVLQGLLVVQPVAAVSALVVLIPAGLNWPEIVLLTGWMVAVSSFYVVMST
                     GLFLLFPAFSEKPMEVLGNAVLMMAISFLLFIFSFAFFGEEGGLYALLLASAVLGTSF
                     LFMGWRKLVRLE"
     gene            6704..7441
                     /locus_tag="PKM11_07445"
     CDS             6704..7441
                     /locus_tag="PKM11_07445"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HNX48373.1"
                     /translation="MPKPPATSEAQLKRQLSWLGEHWEWTMRTLVKERHGLTALDVGC
                     GPGLVMERFSPFLKVTGMDIDPEMVRQVRERGMEAVLGDAQDLPFEDDSFDIVYCAFT
                     MLWLPDRQKAMQEMARVARQCVVCLAEPDYGRRSCWPPEVAQLDEALVRSLRAEGADP
                     FTGRDLDRLMKKAGLQVDHGVYEGNWTGTRLRDEAEAEWETLSRAVKGLVDDERLART
                     KKAWDAALADGTLVLINPVYHAIGWKR"
     gene            complement(7442..8791)
                     /locus_tag="PKM11_07450"
     CDS             complement(7442..8791)
                     /locus_tag="PKM11_07450"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX48374.1"
                     /translation="MTLKNWWRELNGKGLRQGVYKYDGSGDLKGHRFHLRIDSESKGA
                     LLIDASSIIFLNGTALDYVRCVLEDRNEKGVAKYMHRRYKNLDRSKVREHLDLVRSQL
                     SEFLKGDNEVLGMIGPDKPSIGKDDFPAPYRMDLALTYRCQNHCGHCYNEPRELKELT
                     AEQWKQVITKTWELGIPHVIFTGGEPTECDALPELVSWSEKYGQVTGLVSNGRNLAKA
                     GYLHDLVARGLDHVQITVLSSNEEVHDRLAGSAGAWKETIEGLRTALSEDLYVSTNTT
                     IMRSNIDSVEDTMRFLISLGVRNIAFNGLIRSGKGVDAEGISYQELAVALDSLKRIAS
                     DSGVKLIWYTPTPYHEFNPINHGLGIKQCTACALNMAVEPDGTVLPCQSYYRPLGNIL
                     TDDWDRIWNHELCKRIRNRDYLDGDCVECGMNEVCGGGCPLSREHGDYICLDRHSHM"
     gene            complement(8788..>9175)
                     /locus_tag="PKM11_07455"
     CDS             complement(8788..>9175)
                     /locus_tag="PKM11_07455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48375.1"
                     /translation="AWEQVKAAGTPDDAAFQLEKNNEWMMLDRDYPGRMQRDILVLPL
                     FIHRPIPGGAGPSLPNVDLGKMANDYVSNVRNAANNLVNDMRGISNDVVKVTNPAPVS
                     NSGHVSSGSHCACACACACACAGGGR"
BASE COUNT         1727 a         2778 c         2756 g         1914 t
ORIGIN      
        1 atcatggtca acgacgcctg cgcgtccgtg tcgatacacg acatctatca cgacaaccat
       61 ccgctgatca agacccatgt gcacaaccat ctgggtaacc acaagtgcat gaacatgatg
      121 gtgcttagcg gggaagcggc gcagataaac gagctactgg accagatgta tcgtctggaa
      181 ggtatcgcct atctgaagtt catacgttcc tgagcttctc caccggataa ccgttcgctt
      241 tccaggaacc gaggccgccc agcattatcc tgacgttggt gatcccgctg ttgcgcagca
      301 ggcttgcggc gatgccgccc cggtagccgg agccgcagaa gagaaccatc tcccggtccc
      361 tcggaagttc ggaggacctc tccatcaatc ttccgaggtg caacagcatc gcccccggga
      421 tggctccgga accaagctcc cggcggtccc gcagatcgac caacaacata tcctccccgg
      481 ccagctgcct tctgcgtatc tcgtgcaccg tggacgccgc gatggtcgac gtggcgttcc
      541 cgccctttat ccaggattcc atgccgtggc cgagatgccc gatgatgtcc tcatacccga
      601 tacggatgag atatcgaacg gcaaggtcca cctgttgctg cctctccgcc acgatgatca
      661 gcggccgtcc ataaggtatg gcgtatccgc cgtatatcgg cagaccgttc aaccagacgt
      721 tcagcgctcc cggcacgtgc gccgcggcga agttgtgcgg ctcccggacg tccaggacca
      781 atgccccgcc ctcctgggcc tccatcacct tcttgggggg aaggggcgga ggctgcggca
      841 gcgtgccgaa gattataggg ccattgaggt tcagagcctc catccggctg aaataggggg
      901 gtctctccat gccctcgccc atcttggcca tcatgaagtc cagtttgctc atcgatagag
      961 cgtgattgtc ccggacctcc agccctatgg tggtcatctc cctttccgag atgtcatgac
     1021 cgcaggccga accggcgccg tgggccggga gcaccatgat ctccgggccg agcggaacga
     1081 tgcgttcgtg cagagaacgg tacagcatct ccgacaggtc ccgggtgctc tccggaccgg
     1141 tgaggtccgt acgcccgacg tcgccggaga acagcgtgtc cccggagaag agcaggaacg
     1201 gcccgcgatc gtcagagacc agatagcaat ggctctcata ggtgtgtccg ggggtgtgca
     1261 tcgcccttat gatgagatcg cccagccgga actcctgccc gtcctcgagc ggattgccgt
     1321 aaccgaactc caattggtcg ccgtggtaga tcgccgcgcc ggtggcgttg gccagttcta
     1381 gcgccccgga aacatagtcc tcgttgcggt gcgtctccag gaccaggacc acccgggcac
     1441 ccctttccct agctaacgtg agataatcgt caacgtcccg acgagggtcg atgaccgccg
     1501 cctcttcgtt cgactccaga taataggaga tgtgcgccag accctccgac ctcaccctct
     1561 tcaagaacat gaccctcggt aattagtggg aagaggtaaa aacccatcac cttagcccgt
     1621 ccgttcgaac ccttcctcga tcagcgcctg aaccgcttcg tccttacggt ccaaggggac
     1681 gagcaggtgg tcgtaacgga aggtggagat gacgaatatc ggtattccgg cctcggctag
     1741 cgcatccgag gcacgggcca gtatgcccac cgtcgaaagg tcgaaaggac ccatggtcat
     1801 gcaggcgtac ggaccgttgg cctccggccc ggcttccggg gagatgaccg tcgtctcgtc
     1861 cccctcgtcc acggtggcga agcgctcccc tcgaaattca ttgttccgtt gcaaacgatg
     1921 cacgtagagc ggggggcggt ccgaccagaa cttcggcatg aacatctatt ggcgtttcgt
     1981 ctgataagca tgaccgtcga ggcgcctcat cggcctcttg cggcggtgca tgggaccgtc
     2041 cgtcatctta ttgctaccga cgtacggaac gagagagcgt gatgcggcgg cacaggacga
     2101 aggggatgat gagaggtact cttgcgcgtt catgaccctc ccaaccgacc aagggtatat
     2161 accacattca ccgggatgat cgaaagtggt cggcgaaagg aacgctgatt ctaatatgta
     2221 cgaacggcat ggggtcggca tcacaccatg gcgtccgtcc ggaggaggct gagcgtaggt
     2281 tgcgaacgaa ggaaggtcag ggggacaagg tcagcctagg ggaccggcta cgggtcctga
     2341 tgttgaaggg tgatctcaaa cgcaagctcc tggccatagt catactcggc ctgttgatct
     2401 acgggttggt catcgccttg gacggtctcc tgataaggcc cctcctcggc gacgttctca
     2461 gcgaccccac cgacctcgat ttctacaggg ccagggcatc taatattctg gaagggaagg
     2521 tcccttacgt cgatttcacc tccgaatcac cgccgctgat catgtatctg ttcaccatcc
     2581 cgcaactgac cgggggatcg gtccaggcct atcaactttt cttcaccgcg ttcgccatat
     2641 tgacctcggc gacgttcttc ctgttgctta ggagatatga tgaaagaaag gccatggccg
     2701 cctccatact gtacctcgtc taccctctgg gaatgatgga gttcggtttc ggcgtacagg
     2761 acgagtcgat caccatcttc ctgttcgtcc tgcccttgct gcttctgctc caccagaggg
     2821 ccgccgcctc cggggcggcc tcgttccttg gcgttctcac gaagatgttc aacgtgatcg
     2881 tgttgccgtg gaccttcctg cacagcgata acaagggacg cttgaacatg gtgctggcct
     2941 ttggattcct ggccttggtg gtcatcctcc cgttcatgct gctatatccg ggggacctac
     3001 cgtccttcac ctactatttc ctgggccatc cggagacccc gaccggcggg tcgtccatca
     3061 gcccctggca ttacttaggt gagctggggt tcggccttcc gggctgggct ggggtagccc
     3121 ttacgctcgt gggactcggc gccgcttcgc tttacgccta ttggaagaag ttatccctgt
     3181 ggcagggagc gaccttggtc accatggtat tcttcctgac ctatccgaag atccttctgg
     3241 tctacttcat gatgccaggc gtgcttttgc tgatgtgggg cgtggaagac cgcaaggtgg
     3301 tgctcaagct caccgcgatg ctcgttcccc tgttcctgtc cgtggccatc accggcaacg
     3361 gcaaggtgcc tatgatggac ggaccggggg tgtggcttat cggcatcgtc ctgagcctgg
     3421 tgggatgggc gctcttcgtg cacgcctggt ggaaggtgaa ggacgaaaga ccgttcttcg
     3481 aacgcgccga aggatgatca cttgctggtg acctgcactc ccactatacc aacgacgatg
     3541 agcagcacga agaacaggcg cagcaggtcc gacggttcgt tgaagagcaa aatgcccact
     3601 atgagcgccc ctatcgcccc gatcccgacc cagaccgcgt aagccgtacc catcggaatg
     3661 ttcatcttga gcgacctacc gagaagatac atgctgaaga acagaacgat gaaggtggcc
     3721 gccgcccaag gtatgacggt gaagccttcg gagagcttca tggcggtgac ccagaccggt
     3781 tccagcagac cggcgatgac cagcatggcc caggccgggt ccctagcctt tcccgcggcc
     3841 ggaacgtcct cgggcatctc acacccccgc ggtcatctgc acgccggcga tcccgatgac
     3901 gatgagcagg atgaagaaca tccggaccag ttccgccctc tccttgaaga gcattatccc
     3961 ggcgatcagg gcgccgaccg caccgatccc ggtccatacc gcgtacgccg ttcccatggg
     4021 caggtccatg tctatcgcca aagcaagaaa gtacatgctg gcgaatatga agaccacggt
     4081 gaaggcgctc catcccaggc gcttgaaccc ttcggacttc ttgagcccga tcacccagca
     4141 gggctccatg aaaccagcta tcaccaggaa gacccaggcc agggagatca tgtggtcggg
     4201 gagaaacgat tccgtataaa caagtatcct cgttgtcatc cgaaccgctt ccgtcatccc
     4261 ggcaggtgaa gttctaatac ctgacgctgc aaggacgccc tgtgagcgac gcggccacta
     4321 gggttccgat cattgatgct tcatccctca gcaaaaggta tggacgccgg ggggaggtcc
     4381 gggcggtgga tggcatttcc ctgaccgtat atccgggtga gacgttcgga ctgttgggac
     4441 cgaacggttc cggcaagacc accaccatcc gcatgctgaa cggcataatc aggcctagcg
     4501 ccgggaaggc gtttgtgaac ggtttcgaca tctccacgca gatcgatgat gttaaacgtt
     4561 ccacgggact tctggcggaa tcgcccggcc tctacgagaa actgagtccc agggaatatc
     4621 tggagttcgt cggttcgcta tacgacgttg aaaggtcttt gcttaaggac cgagcggacc
     4681 gcttgctgga gctcttcgac ctcaaacagc gtggcgatga tcttatggaa gggttcagcc
     4741 ggggcatgaa gcagaaggtg ctcatcgccg cggcgctgat acacgacccc ccgatcgtgt
     4801 tcctggacga gccgacctcc gccctggacc ccctggcctc gctggtggtt cgagatctca
     4861 ttaaggacct ggcggagaag gccggcaaga ccgtgttcgt gagcagccac atcctgccgt
     4921 tgatggagga ggtctgcgac cgcatcgcga taatcgatca cggaaaggtg gcggcggcgg
     4981 gaaccgtcac cgagatactc gagcagtcgg gaactttcac cctggaggat gccttcatca
     5041 aattaactgg cggagccgga cgcccggacg ccctgtcctg gaggaaagcg gttgccaaag
     5101 cctaagtggt ggctgatagc ccgaaacgag tatctgctga agaccagcgg gataaggaga
     5161 tggcgcaggc tcttccctct ggcgctcgtg gccttgctgg cctggtacgt ggtgttcgcc
     5221 gcgccggcgg tgttctccct ggcctcggac ctcaccaagg acctgctgct ctccgaagcg
     5281 gcgttatcct tcatgcaggt catgcttttc gtgatcttca tcagcgtctt caccgtgccg
     5341 atcatccaga ccctgcagga taccaacctg gcaccgctgg agactctgct ctcggcaccg
     5401 gtacgaccgg cggacgtgct gctgggcaag ttccttggga tgctgcccac ctattccatt
     5461 ctgataaccg tgctggccgg gacgttcctg gcgttgttca ttcccttcgg tatgaccctg
     5521 gaccaggtgc tgttgtcgat cctggtcttc atcctggtcg ttctcatctc gctttggctc
     5581 gggcttctga ccgcggcgat gttgaaggcc cgtctgaacc gaagccagaa gggaagggag
     5641 gccgggcagg cgctggcctt gatcatcgct ctgcccctgg ttggtctgat gtacctatcc
     5701 atgaacgggg agatgatggg cgccctgcag ggcaagggcg cttcgctctc tgacgccttc
     5761 tggctgcttc ccagctcctg gggggcggac ctggtgctgc gcttcctcca gcacccggga
     5821 gacctgggtt atgaggccgg aagcaccgcc ctgggactgc tggggctttc tggaacactg
     5881 gtgctctccc tgatcgccgg agtaaggttg tccggtaggg cgtacgacct ggagccggtg
     5941 tccttcgcca ccccccgggc ggcgccggaa gggcacctgt acgcctacgc tcgcgccctg
     6001 gcagggaaca agcacctggg tacggtgctg gtcacggtga tgaaggacta cggcagaagg
     6061 ctggagaacc tttcgcgtat catctacatc ctgggactgg tggtcatgat ggaggtcttc
     6121 atgctcggtt cccttccccc gggaaattac gtgaccttgg ccttgctgac cgcctcctgg
     6181 ctgatggcct tcctgtgcgt cttcgtggtc ggtgaggtga ccgcccgcgg caaggacaac
     6241 ctgttcatct accgcaaggc tccgcggggg gagacgagat tggtgctggc ccgggtcctg
     6301 caggggttgc tggtggtcca gccggtggcg gcggtgtcgg cgttggtggt gctgatcccg
     6361 gcgggattga actggccgga gatcgtgctg ctgaccggct ggatggtcgc cgtctcctcc
     6421 ttctacgtgg tcatgtccac cggactgttc ctgctgttcc cggccttcag cgagaagccc
     6481 atggaggtgc tcgggaacgc ggtgctcatg atggccatat cgttcctgct gttcatcttc
     6541 agcttcgcct tcttcgggga ggagggagga ctgtacgccc tgctcctggc gagcgcggtg
     6601 ctgggaacct cgttcctgtt catgggatgg aggaagctgg tgcggctgga atgaggcgtg
     6661 ctgtttcgac accattatcc gacgacaggc gttattaggt ggcgtgccaa agcctccggc
     6721 gacgtccgaa gcgcaattga agcgccagct gtcctggctc ggggagcact gggaatggac
     6781 catgcgtacc ctggtgaagg aacgtcacgg cctgaccgcc ctggacgtag gctgcggtcc
     6841 cggcctggtc atggaacggt tctccccctt cctgaaggtg accggtatgg acatcgatcc
     6901 ggagatggtc cggcaggtgc gggagagggg aatggaggcg gttctgggag acgcgcagga
     6961 cctgcccttt gaagatgaca gcttcgacat cgtctactgc gctttcacca tgctctggct
     7021 gcccgaccgg cagaaggcca tgcaggagat ggccagggtc gcacgacaat gcgtggtctg
     7081 cctggccgag ccggactacg gcagacgatc gtgctggcct ccggaagtgg cccagctgga
     7141 cgaggccttg gttcgatcgc tgcgggccga gggcgccgac ccgttcacgg gaagggacct
     7201 ggaccgcctg atgaaaaagg ccggtctaca ggtcgatcac ggggtgtacg agggtaattg
     7261 gaccggtacg cggctcaggg acgaggcgga ggcggaatgg gaaacgctat ctcgagccgt
     7321 caagggattg gtggacgatg agaggttggc cagaacgaag aaggcctggg acgcggcctt
     7381 ggccgacggt accctggtgc tgatcaatcc cgtctaccac gccatcggct ggaaacggtg
     7441 atcacatgtg cgagtgccgg tcgaggcaga tgtaatcgcc gtgctccctc gacagcggac
     7501 agccaccccc gcagacctcg ttcatcccgc actcgacgca gtccccgtcc aggtaatccc
     7561 ggtttcggat gcgcttgcac agttcatggt tccagatcct atcccaatcg tcggtgagga
     7621 tgttccccaa cggccggtaa tagctctggc acggaagcac cgtaccgtcc ggctccacgg
     7681 ccatgttcag cgcgcaggcg gtgcactgct ttatgcccag gccatgattg atcggattga
     7741 actcgtggta aggcgtcggc gtgtaccaga tgagctttac tccgctgtcg gacgctatgc
     7801 gcttgagcga atccaacgct accgcgagct cctggtagct gatgccctcc gcgtccactc
     7861 cctttccgga acggatcaga ccgttgaagg cgatgttcct tacgcctagt gaaatgagga
     7921 agcgcatggt atcctcgacg ctgtcgatat tggagcgcat gatggtggtg ttggtgctca
     7981 cgtaaaggtc ctcgctcaag gccgtccgaa gaccttctat ggtctccttc caggcccccg
     8041 cgcttccggc caaacggtca tggacctcct cgttagacga tagaacggtt atctgcacgt
     8101 ggtccagtcc cctggcgacc aggtcatgca ggtaacccgc cttcgctaag ttgcggccgt
     8161 tgctcaccag cccggtcacc tgaccgtatt tttcggacca agacaccagt tccggcaagg
     8221 cgtcgcattc cgtcggctcg ccgccggtga agatgacgtg cgggataccg agctcccacg
     8281 ttttcgtgat gacctgcttc cattgctccg ccgtaagctc cttcagctcg cgcggttcgt
     8341 tgtagcaatg accgcaatgg ttctggcaac gatacgtcaa cgccaggtcc atgcggtacg
     8401 gggccgggaa atcgtccttg cctatcgacg gtttatcggg accgatcatg cccaaaacct
     8461 cgttgtcccc tttcaggaac tcgctgagct gcgatcggac caggtcgaga tgctcccgca
     8521 ccttgctccg gtccagattt ttatagcgcc ggtgcatgta cttggccacg cccttttcat
     8581 ttcggtcctc gagaacgcag cgcacgtagt ccagggccgt tccgttcagg aagattatgc
     8641 tcgaagcgtc aataagaagc gcacccttgc tctctgaatc tatcctgagg tgaaaacggt
     8701 gtccctttag atctcctgaa ccatcgtact tgtagacgcc ctgacggaga ccttttccgt
     8761 tcagctcgcg ccaccagttc ttcaacgtca tcgtccacct cctgcgcacg cacaggcaca
     8821 ggcgcaagcg caggcgcagt gcgacccgct cgatacgtgc ccgctattag acaccggagc
     8881 gggattggtc accttgacca cgtcgttgga tatacctcgc atgtcgttga ccagattgtt
     8941 ggcggcgttc cgaacgttgc tgacgtaatc attggccatc ttgcccaagt ccacgttggg
     9001 tagggaaggc ccggctccgc cggggatcgg ccggtggatg aacaacggaa gcacaagtat
     9061 gtctctctgc atgcgccccg gataatcgcg gtccagcatc atccattcgt tgttcttctc
     9121 caattggaaa gctgcatcgt ccggcgttcc ggcggccttg acctgctccc aagcc
//
LOCUS       DAOPZI010000045         8891 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_9346_length_8891_cov_9.737664, whole genome shotgun sequence.
ACCESSION   DAOPZI010000045 DAOPZI010000000
VERSION     DAOPZI010000045.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 8891)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8891)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8891
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_9346_length_8891_cov_9.737664"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            44..466
                     /locus_tag="PKM11_07460"
     CDS             44..466
                     /locus_tag="PKM11_07460"
                     /inference="COORDINATES: protein motif:HMM:NF019407.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin"
                     /protein_id="HNX48376.1"
                     /translation="MKAFWRRNDNAVSPVIATILVVAITVVLAAVLYVMVMGFEPGGD
                     VNPPQASLNADEGKLVLTISKSYDIDDGILQVTIDGGEKLDIVNGTISGTVAFVDSGN
                     DGKIGSNDYFTNSATTTSIIKIIWTSGDVSQVIAEGEV"
     gene            complement(487..924)
                     /locus_tag="PKM11_07465"
     CDS             complement(487..924)
                     /locus_tag="PKM11_07465"
                     /inference="COORDINATES: protein motif:HMM:NF018028.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HNX48377.1"
                     /translation="MEMPTGYDLIEHNHDFRMHLLKRLAAGLLDAAVVFIPVTLIIFL
                     MGLEPREILTGTLTGFGWFFYSVISEARTGTSLGKKILGLTVASKEGPMTLSQAVVRN
                     VPKMFWFIFLPVDVLVGLSRDGDPRQRWVDGVASTTVIKLDRK"
     gene            1227..1553
                     /locus_tag="PKM11_07470"
     CDS             1227..1553
                     /locus_tag="PKM11_07470"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48378.1"
                     /translation="MLKSNVDPRAIVGGLLAAVAVLGLLLESTWYIWLLLLAVGVVLI
                     VVTITDRFEYECQKCHGRYKLGVKGIIASKHGRDANGSWAISRCPHCRAITKAKESRS
                     YGKEKV"
     gene            1534..1980
                     /locus_tag="PKM11_07475"
     CDS             1534..1980
                     /locus_tag="PKM11_07475"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: protein motif:HMM:NF013607.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase ArsC"
                     /protein_id="HNX48379.1"
                     /translation="MGRRRFRDTVSRRTILFICIGNASRSQMAEGYVNAKMGDRYQAS
                     SAGLNPERVSRKAIAVMNEIGIDISEHRSKSVEEFYGKEFDYVVTLCDEAEDECPHFL
                     NGKDYIHKGFPDPCKARGTDDELLIVYRKTRDDLIKWIDNIFGSDA"
     gene            1977..2507
                     /locus_tag="PKM11_07480"
     CDS             1977..2507
                     /locus_tag="PKM11_07480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF367 family protein"
                     /protein_id="HNX48380.1"
                     /translation="MSTVYVYDERDCDPKKCTSRKMVKFQLAKELPNLKAVPYGVVVL
                     DPFAQKAVSREDSERVKAHGVLVMDLSWENIEHFPTVRRDAAHRALPYLLAANPVNWG
                     KPMRLTSAEAVAATLYIVGEKEQAHQVLAKFNWGEQFLILNQELLERYSSVETSQEVV
                     AIQWDYCERPEPDGQE"
     gene            2604..>5609
                     /locus_tag="PKM11_07485"
     CDS             2604..>5609
                     /locus_tag="PKM11_07485"
                     /inference="COORDINATES: protein motif:HMM:NF026240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HNX48381.1"
                     /translation="MPIDYTDEDIVARWEEFLEAEENRLKLLELTDRLPDLRSLTVTY
                     SELDRFDPDFASFILSHPDRALKKGEDIIKRLTNTARSTADVHLRIRELPRDSRIDIR
                     DLRSEDLGKLISVEGLVRKATEVRPRLILGVFKCMRCPARILEPQEGLYFREPMECYK
                     EQEGCGRTAGSTKFQLLTEESFYVDTQKVEMQESPEGLRGGAQPERLAAFLEDDLAGK
                     ISPGDRVVLNGILRSQQKGDRIKSTLFDIDLAVVSTEFEQHEYEEVVISDEDEALIKK
                     EAKDPEVFRKIVGSIAPAIHGYDEVKESIALQLFGGTAKLLEDGTKIRGDIHILLVGD
                     PGVAKCVTSDAKVLMGDCTEKNIKELVDHWLSVNEPKEVDDGEYADAEFDVMTFTSRG
                     RIEKGKAVRVWKRDSPRRLIRFTTEGGRTLTVTPTHPLFVQNAYYMAQRSADKILEGN
                     YLAITSDKGPDGNFCGFDRGFGWDQIVKREDVKREEEFVYDIEVADTHIFVANGILSH
                     NSQILRYMSEMAPRGIYASGKSSSAAGLCVAPESLIEVDGKQMPIGDFVESRMRSPME
                     IEPGVWRQETRVNGVVTVSADRHMDVRPVVSLFRLRTPSFLVELSTDAGNSVRTTPET
                     MVRTRNGHQDRWVKSSDIVVGDTVLTAPSGSSKGEVSLSKVVKVAEVRENLPPHVYDL
                     TVEGAHSFVANGFLVHNTAAAVKDEFGDGRWTLEAGALVLADKGLAAIDELDKMSDQD
                     RSSMHEAMESQRVSVAKAGITASLQCRCSMLGAANPKLGRFDDAEPLASQINMPPALL
                     SRFDLIFALTDKPNAAKDLKIAEHILKGHVRGELRNVPNPESIKGIDYQRIMEETGVL
                     RPIYDREFMRKFVAYAKRYTPVLTDDARQMIIDKYLAIRKLGEKVGSSVPITARQLEA
                     FIRLSEASARIRLSPIVEIEDADRAIKIVEHYLKKMASDEGTIDVDKLMTGTTRNERN
                     RISLVRQLIHEHSDPSSGASEVTLIQRAAD"
     assembly_gap    5610..5709
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <5710..5904
                     /locus_tag="PKM11_07490"
     CDS             <5710..5904
                     /locus_tag="PKM11_07490"
                     /inference="COORDINATES: protein motif:HMM:NF016157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF424 family protein"
                     /protein_id="HNX48382.1"
                     /translation="LDVSDEFYGGDRGDEEMLLNRLRMATMANLVGENVCRIAAEHDF
                     IDRECVITIEGVPHAQMVRY"
     gene            5906..6952
                     /locus_tag="PKM11_07495"
     CDS             5906..6952
                     /locus_tag="PKM11_07495"
                     /inference="COORDINATES: protein motif:HMM:NF016842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NMD3-related protein"
                     /protein_id="HNX48383.1"
                     /translation="MSFCVKCGVDGPTYRSLCESCFLEGKVFTALPDHVDVFQCGHCG
                     DYLLDGKWVDIEAREEVSEKATELALQITKDAEPVNIALHGEKIDEANYHVGMTIAMT
                     VEGLEVNEARTTIVRFKNTSCPRCNKLMGNYYEGTLQVRTRDRKMSDEQREEILDRIL
                     KMMDEHTKDNRELFISKINRLHTKEGGLDVILSSSVVGKHMAHAIADQYAAEVKETAK
                     LVTQKQGKDLYRVTFVVRLPAYRFGDIVRYENKLHLVGALRSNSTKLTNLKTSQGLMV
                     SNSDMISAKVVGRKEDIIEAVVVTETDREVQVMHPTNFKVFDLKKPPKFERKGDTVKI
                     FQLEEEFFLLPLQG"
     gene            complement(6967..7797)
                     /locus_tag="PKM11_07500"
     CDS             complement(6967..7797)
                     /locus_tag="PKM11_07500"
                     /inference="COORDINATES: protein motif:HMM:NF024091.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HNX48384.1"
                     /translation="MESANVVNNRERLPSDLQQVMTVAKYDVLKHLRSKRLLGLLVLE
                     GLLLGLTFGLPIALGADAAEDPSDYISAFIGWVDILIVLGATMFAGDAIVSEFQSRTG
                     YLLFPNPVKRSTIFIGKYLSTLGIIILMLLVYYGIAALLTFAMTGGGTVLAVYSMLFA
                     FAYGAAAAALGFLISSIFKGSTGSLILTFFTLLMILPLIAQLLPIGEIKPWFMLTFCG
                     GVISTIMIEPYPTDVMEPIMNYWIYYPEVGLSLVVLAVYIAVCLGLGMYLFKRREMVS
                     "
     gene            complement(7802..8740)
                     /locus_tag="PKM11_07505"
     CDS             complement(7802..8740)
                     /locus_tag="PKM11_07505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HNX48385.1"
                     /translation="MDAPIQVHGLTKVYGGGFRAVDALELNVPDRSFMGFLGPNGAGK
                     TTTIKIITNMLTATSGEAVINGVSVMQDPKTALADVGAVVETPEFYPYLTPMETLHYL
                     GALRGMTVTESTNRGRDLLDMVKLTEWKDQRVGKFSKGMKQRLAIAQALLPEPSIIIL
                     DEPTSGLDPRGMVEVRDILKHLKKMDVTVLMSSHLLNEVQEVCTDVALINRGKLLRSG
                     SVADLLDEVKARKIDVQTRRPLTPDMFDRLRSVDGVKGFSITGELTFAIDFEGEEDAQ
                     ARLLIELQNLGLLVVSFKESGLALESLYMSLIMESR"
BASE COUNT         1967 a         2505 c         2672 g         1647 t
ORIGIN      
        1 tcgaattata gtctggcagg gcgacctgtc aggtgaccta acaatgaaag cattttggag
       61 aaggaacgac aacgcagtct ccccggtcat cgccaccatc ttggtggtcg cgatcaccgt
      121 ggtcctggcc gctgtgttgt acgtgatggt gatggggttt gagcccggtg gcgatgtcaa
      181 ccccccgcag gccagcctta acgcggacga ggggaagctg gtgctgacca tcagcaaatc
      241 gtacgacatc gatgacggca tactgcaggt gaccattgac ggcggagaaa agctagacat
      301 cgtcaatggg acgatatccg gaacggtggc gttcgtcgac agtggcaatg acggcaagat
      361 cggctcgaac gactacttca cgaacagcgc caccacgaca tcgatcataa agatcatctg
      421 gacctccgga gacgtcagcc aggtcatagc cgagggcgag gtctgacgct gcgttaaggg
      481 atcaaactac ttccggtcca attttattac cgtggtagag gctactccgt ccacccatct
      541 ctgccggggg tctccgtcgc ggctcagtcc gaccagcacg tccacgggca ggaaaatgaa
      601 ccagaacatc ttcggaacgt tcctgaccac cgcctgggac agggtcatcg gaccttcctt
      661 ggaagccacg gtcaatccca agatcttctt gcccagggag gtgccggtgc gcgcctcgga
      721 gatgacggaa tagaagaacc acccgaaacc ggtcagggtg ccggtcaaga tctcccttgg
      781 ttccagcccc atcaagaaaa taatgagcgt caccggtatg aagacgaccg ccgcatccaa
      841 aagtccggcc gccaaacgct tgagcaggtg catccggaaa tcgtggttgt gctctatcag
      901 atcgtacccg gtcggcatct ccatccctat acgctatata aggcacagaa tattttattc
      961 ttatgccatt aaattaattt caccactcag ctcgcccgtc tctcatcacg aatcagagct
     1021 gggtttatca tcatcgtggc gttagcgcat catacgccct gaacataaat gtatctcgaa
     1081 ggaaggaaga ctatcgaacg tcggaaccaa cggcaccctc ccttatattc gggaaggcga
     1141 tatccgaaca gtcacgatat cattaggtgt cccgtaccgg cccgaggata cgggccgtca
     1201 ctgacatccg catcaggtgt caaataatgc tgaaatcgaa tgtcgatccc cgagcgatcg
     1261 tcggagggct gctggcagcg gtagcggtgc tcggtcttct gctcgaaagc acctggtaca
     1321 tctggttgct gctgttggcc gtcggtgtcg ttctcatcgt cgtcaccatc accgaccgct
     1381 tcgagtacga atgtcagaaa tgccacggcc ggtacaagct cggggtgaaa gggattatcg
     1441 cctccaagca cgggcgggac gccaacggga gctgggccat ctcccgctgc cctcactgca
     1501 gggcgatcac caaggccaag gagtcacgat catatgggaa ggagaaggtt tagagacacc
     1561 gtatcaagga ggaccatcct cttcatctgc atcgggaacg cctcgcgttc gcagatggcg
     1621 gaaggttacg tgaacgccaa gatgggcgat aggtatcaag cgagcagcgc cggcctgaac
     1681 ccagaaaggg tgagccgcaa ggccatcgcg gtcatgaacg agatcggcat cgacatatcg
     1741 gagcaccgct ccaagagcgt ggaggagttc tacggcaagg agttcgatta tgtggtcacc
     1801 ctatgcgacg aggcagagga cgagtgcccg cacttcctga acggcaagga ctatattcac
     1861 aagggcttcc cggacccctg caaggcgcgg ggcactgacg acgaactgct catcgtctac
     1921 cgcaagacca gggacgacct gatcaagtgg atcgacaaca tctttggctc cgacgcatga
     1981 gcaccgtcta cgtttacgac gagagggatt gcgaccccaa gaaatgcacc tcccgcaaga
     2041 tggtgaagtt ccagctggct aaggagcttc cgaacctcaa ggccgtgccc tatggcgtcg
     2101 tcgttctgga ccccttcgcc cagaaggccg tgtcccgcga ggattccgaa agagtgaagg
     2161 cgcacggggt tctggtcatg gacctctctt gggagaacat cgagcatttt cccacagttc
     2221 gaagggacgc cgcgcaccgc gcgttgccgt atctgttggc ggccaacccg gtgaactggg
     2281 ggaaacctat gcggctgacg agcgccgagg cggtggcggc gacgctatat atcgtcgggg
     2341 agaaggagca ggcgcatcag gttctcgcca agttcaactg gggggagcag ttccttatcc
     2401 tgaaccagga gctgctggag cgttactcct ccgtggagac cagtcaggag gtggtggcca
     2461 tccaatggga ctactgtgag agacctgagc cggacgggca ggagtaaagg taaggcaacg
     2521 atatttgtaa atccgtccga taagatacct tgtttcccga agttccatta cctgaaaccc
     2581 cttaggacca cggagtgatg gttttgccga tcgattacac tgatgaggac atagtcgcgc
     2641 gatgggagga gttcctggag gccgaggaga accgcctcaa gctgctggag ctcaccgacc
     2701 ggcttcccga cctgaggagc ttgaccgtca cctattcgga gctggaccga ttcgatcccg
     2761 acttcgccag cttcatcctg agccacccgg accgggccct gaagaagggc gaggacatta
     2821 tcaaacgcct caccaacacc gcccgctcga cggccgatgt gcatctgcgc atacgcgaac
     2881 tcccaaggga cagtcgcatc gatattcgcg atctgagaag cgaggacctg ggcaagctga
     2941 tctccgtgga aggtctggtt cgcaaggcca ccgaggtgcg cccccgtttg atactgggcg
     3001 tgttcaaatg catgcgctgc cccgcccgta tattggaacc gcaggaaggg ctgtacttcc
     3061 gggagcccat ggagtgctac aaggagcagg aaggctgcgg acggacggcg ggaagcacca
     3121 agttccagct cctcaccgag gagtcatttt atgtcgacac ccagaaggtg gagatgcagg
     3181 aatcgccgga aggcttgcgc ggaggggcgc agcccgagcg tctcgccgcc ttcctggagg
     3241 atgatcttgc cgggaaaata tcgccaggcg accgtgtcgt tctcaacggc atcctgcgta
     3301 gccagcagaa aggggaccgc ataaaatcca cgttattcga catcgacctg gcggtcgtgt
     3361 ccacggagtt cgagcagcac gagtacgaag aagtggtgat ctcggacgag gatgaggcgc
     3421 tgatcaagaa ggaggcgaag gaccccgagg tcttccgcaa gatcgtgggc tccatcgccc
     3481 cggccatcca cggttacgac gaggtcaagg agagcatcgc gttgcagctc ttcggcggca
     3541 ccgccaagct tctggaggac ggaaccaaga tcagggggga cattcatatt ctgttggtcg
     3601 gagaccccgg ggtcgcaaag tgcgtcacca gcgacgccaa ggtgctcatg ggcgactgca
     3661 ccgagaagaa catcaaggag ctcgtggacc actggctttc ggtcaacgaa ccaaaggagg
     3721 tggacgatgg ggagtacgct gacgctgagt ttgacgtgat gaccttcacc tcccgcgggc
     3781 gcatcgaaaa gggtaaggca gtccgcgtct ggaagaggga ctcgccccgg cggctgatac
     3841 ggttcaccac cgagggtgga agaactctga ccgtcactcc gacgcatccg ctgttcgtgc
     3901 agaacgccta ttacatggcg caacgttcgg ccgacaagat cctggaaggt aactatctgg
     3961 cgataacttc cgataaaggt ccggacggca acttctgcgg cttcgaccgt gggttcggct
     4021 gggaccagat cgtgaaacga gaggacgtga aacgcgagga ggagttcgtt tacgacatcg
     4081 aggtcgccga cacgcatatc ttcgtagcga acggcatact ctctcacaac agccagatat
     4141 tgcgctacat gtcggagatg gctccccgcg ggatctacgc ctccggaaag agctcctcgg
     4201 cggccggtct ttgcgtagca ccggaatcgc tcatcgaggt ggacggaaaa cagatgccga
     4261 taggcgactt cgtcgagtcg cgcatgcgct ccccgatgga gatagagccg ggggtttggc
     4321 gacaggagac ccgggtgaac ggagtggtca ccgtgtcggc cgatcgtcat atggatgtcc
     4381 gaccggtcgt ttcgttgttc cgcctgcgaa ccccttcatt tcttgtggaa ctctctaccg
     4441 acgctggtaa cagcgttcgt accaccccgg aaaccatggt tcgaaccagg aacgggcatc
     4501 aggaccggtg ggtcaaatcg tctgacatcg tggtcgggga cacggtgcta acagcaccat
     4561 ctggctcatc gaagggagag gtctccctga gcaaggtcgt caaggtcgcg gaggtgcggg
     4621 agaaccttcc gccgcacgtg tacgatctga cggtcgaggg ggcgcacagc ttcgtcgcca
     4681 acggatttct tgtgcacaac accgccgccg cggtgaagga cgagttcggg gacgggcgtt
     4741 ggaccttgga ggccggtgcc ctggtcctag cggacaaagg actggcggcc atagacgagc
     4801 tggacaagat gtccgatcag gaccgctcgt caatgcatga ggccatggag tcgcagaggg
     4861 tgagcgtggc caaggccggt atcacggcgt ctctccagtg ccgctgttcc atgctcgggg
     4921 ccgcgaaccc gaaattaggg cgtttcgatg atgccgagcc gttggcgtct cagatcaaca
     4981 tgcctccggc gctgctatcc cgtttcgatc tgatattcgc tctgacggac aagcccaacg
     5041 cggccaagga cctgaagatc gccgagcaca tcctgaaagg gcacgtgcgc ggcgaacttc
     5101 ggaacgtgcc aaacccggag tccatcaaag gcatcgatta tcagcgcatc atggaggaga
     5161 ccggggttct gcggccgata tacgacaggg agttcatgcg caagttcgtt gcttacgcca
     5221 agcgatacac gccggtgctg acggacgatg ccaggcagat gataatcgac aagtatctgg
     5281 ccataaggaa gctgggagag aaggtcggtt cgtccgtgcc cataacggca aggcagctgg
     5341 aggccttcat acggctttcg gaagcgtccg cccgtatacg cctctctccg atagtggaga
     5401 tcgaggacgc cgaccgggcc atcaagatcg tggagcatta cctgaagaag atggcctccg
     5461 acgaagggac gatagacgtg gacaagctga tgaccggcac cactcggaac gagcgaaacc
     5521 gcatctcgct ggtgaggcag ctcatacacg agcactccga cccgtcgtcc ggagcgtccg
     5581 aggtcaccct gatccagagg gcggccgatn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5701 nnnnnnnnnc tggatgtcag cgacgaattc tacggaggcg accgcgggga cgaggagatg
     5761 ctcctgaacc gattgaggat ggccaccatg gccaacctgg tcggggagaa cgtttgccgc
     5821 atcgccgccg agcatgattt cattgaccgg gagtgcgtga tcaccatcga aggcgttccg
     5881 cacgcccaga tggtaaggta ttgaaatgtc cttctgcgta aagtgtgggg tggacggtcc
     5941 gacgtaccgt tcgttgtgcg aatcatgttt cctggagggc aaggtgttca ccgccctgcc
     6001 ggaccacgtg gacgtgttcc agtgcggcca ctgcggtgat tatcttttgg acggcaagtg
     6061 ggtggacatc gaggcccgcg aggaagtgtc agaaaaggcc acggaactgg ccttgcagat
     6121 caccaaggac gccgagcctg ttaacatagc gttgcacggc gagaagatcg acgaggcgaa
     6181 ctaccacgtc ggcatgacca tcgccatgac cgtggaaggc ctggaggtga acgaggccag
     6241 gacgacgatc gtccgcttca agaacacctc ctgcccccga tgcaacaagc tgatgggcaa
     6301 ttattacgaa ggcaccttac aggtccgaac cagggaccgc aagatgtccg acgagcagcg
     6361 cgaggagata ctggaccgca tcctcaagat gatggacgag cacaccaagg acaaccgcga
     6421 gttgttcatt tccaagatca accggctcca caccaaggag ggcggcctgg acgtcatcct
     6481 gtcgtcgtcc gtcgtcggca agcacatggc ccacgccatc gcggaccagt acgccgcgga
     6541 ggtcaaggag acggccaagc tggtcaccca gaagcagggc aaggaccttt accgcgttac
     6601 gttcgtagta cgcctaccgg cgtaccgctt cggcgatatc gtgcgctacg agaacaagct
     6661 gcatctggtc ggggcgctgc gttccaactc caccaagctc accaacctca agacctcgca
     6721 agggctcatg gtcagcaaca gcgacatgat ttccgccaag gtggtcgggc gcaaggagga
     6781 catcatcgag gccgtggtcg tcaccgaaac ggaccgcgag gtgcaggtca tgcaccccac
     6841 caacttcaag gtgttcgacc tgaagaagcc gccgaagttc gagcgaaaag gagatacggt
     6901 gaagatattc cagctggagg aggagttctt cctcctgccg ttgcaaggtt gagatttttt
     6961 aggtccttac gagaccatct cccttctctt gaacaggtac atccccagcc ccaggcagac
     7021 ggcgatgtac acggccaaga ccactaggga cagacccacc tcaggatagt agatccagta
     7081 gttcatgatc ggttccatga cgtcggtggg gtacggttcg atcatgatgg tgcttatcac
     7141 gcctccgcag aaggtcagca tgaaccacgg ttttatctct ccgatgggca ggagctgggc
     7201 gatcagcggc aggatcatca gcagggtgaa gaaggtcagt atgagcgatc ccgtggagcc
     7261 tttgaatatc gaggatatca ggaatcccaa cgccgccgcg gccgcgccgt aggcgaaagc
     7321 gaagagcatc gagtacacgg ccagcacggt accgccgccg gtcatggcga aggtcagcaa
     7381 ggccgctatt ccgtaataca cgagcagcat gaggattatg atccccaggg tggagaggta
     7441 cttcccgatg aatatcgtgg aacgcttgac cgggttcggg aagagcaagt atcccgtccg
     7501 ggattggaac tcggacacga tggcgtcccc ggcgaacatg gtcgccccga ggacgatgag
     7561 tatgtccacc cagcctatga atgccgatat atagtcgctg ggatcctccg cggcgtccgc
     7621 cccgagggcg atcggcagtc cgaacgtaag gccgagcaac aaaccctcca gcaccagcag
     7681 gccgagcagc ctcttggagc gcaggtgctt caggacgtcg tacttggcta cggtcatgac
     7741 ctgctgcagg tcggacggaa gccgctcacg gttgtttact acgttggcgc tctccatgat
     7801 atcacctcga ctccatgatc agggacatgt acagcgattc taaggctaga ccggactcct
     7861 tgaacgagac caccagcagc cccaggttct gcagttcgat cagcagacgg gcctgggcgt
     7921 cctcctcccc ctcgaagtcg atggcgaagg tcagctcccc ggtgatgctg aagcccttca
     7981 ccccgtcgac ggagcgcaga cggtcgaaca tgtccggcgt cagcggtctc ctggtctgaa
     8041 catctatctt tctggccttg acctcgtcca gcaggtcggc cacgcttccc gagcgcagaa
     8101 gcttgccccg gttgatcagc gcgacgtcgg tgcacacctc ctgcacctcg ttcagaagat
     8161 gggaggacat cagaacggtc acgtccatct tcttcaggtg cttgagtatg tcgcggacct
     8221 ccaccatgcc tcggggatcg aggccggagg tcggctcgtc caggatgatg atggacggct
     8281 cagggagaag cgcctgggcg atggccaggc gttgtttcat ccctttggag aacttgccca
     8341 cccgctggtc cttccactcg gtcagcttga ccatgtccag caagtcccgt ccccggttgg
     8401 tgctctcggt gacggtcata cctcgcaaag cgccgagata atgaagcgtc tccatcggcg
     8461 tcaggtaggg atagaactcc ggagtctcca ccaccgcccc gacgtcggcc agggcggtct
     8521 tggggtcctg catgacgctg acgccgttga tgacagcctc tccggaggtg gcggtcagca
     8581 tattggtgat tatcttgatg gtggtggtct tgcccgcccc gttggggccg aggaagccca
     8641 tgaatgaccg gtcgggaacg ttcagctcca gagcgtccac cgctcggaag ccgcccccgt
     8701 aaaccttggt cagtccgtgg acctggatag gtgcgtccat gtggatcggg cgattattct
     8761 cgacggacta taattcatta ttgacattac aatccttggt gaccaggacc gggcaggcca
     8821 aggattaatt ccccctgcga caatccagac ggcaagatgt actcgtcgtc actgatcgag
     8881 gagacggtgg t
//
LOCUS       DAOPZI010000046         8158 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_10537_length_8158_cov_8.989387, whole genome shotgun sequence.
ACCESSION   DAOPZI010000046 DAOPZI010000000
VERSION     DAOPZI010000046.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 8158)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 8158)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8158
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10537_length_8158_cov_8.989387"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..654
                     /locus_tag="PKM11_07510"
     CDS             <1..654
                     /locus_tag="PKM11_07510"
                     /inference="COORDINATES: protein motif:HMM:NF024252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX48386.1"
                     /translation="EEGEVGLTSSRTALVPQLPDLDKIRQMRKRLNLSQRELAGLAGV
                     SQSLIAKIERGTIDPSYSNVRKILAAFEEVIRRRKVEGVRSGTQLTVGDLATRGVIFV
                     TPDQTIGEAVERMMKGRFTQLPVIVGERIVGGLTDDAIRDHTIEQTKTRKKTYEEVMR
                     TRIEEIMDAPFPILNEDTPIDLASFHLQREEAILVSRKGAIVGILTSADFLNLGLNQ"
     gene            697..1308
                     /locus_tag="PKM11_07515"
     CDS             697..1308
                     /locus_tag="PKM11_07515"
                     /inference="COORDINATES: protein motif:HMM:NF017026.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="METTL5 family protein"
                     /protein_id="HNX48387.1"
                     /translation="MKRRELEMVLQSLSPFSSPRPELEQYSTPAVMAADLLFDALARG
                     DIEGRKVLDLGCGTGPLGIGAALLGADPVLGFDKDPKALEVASANAAKVGVEMDLHQA
                     DISDVQEKADTVIMNPPFGAQRKGADRPFLTAAMRCAPVIYSLHMSSTEDFVQRFVGR
                     SGFTATPLKRYKFGIPYMFEFHSKAKKEIDVTLFYILRTGVLE"
     gene            1305..1886
                     /locus_tag="PKM11_07520"
     CDS             1305..1886
                     /locus_tag="PKM11_07520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosome complex RNA-binding protein Csl4"
                     /protein_id="HNX48388.1"
                     /translation="MSDKKKVLPGDEVAVAEEYLPADGTYEEDGIVYSALTGELKVND
                     RDKTVSVEAENPMVSLTIGDSVFCEVTDVRASMAICEVVAVEGRSRNITGDTNGTIHV
                     SKISSDYVQDVGREYRPSDIIRAKVMQVRPSIQLNTTQPHFGAVKSLCRNCRSQLKKA
                     DKGLYCDHCEAYESRKVADDYGFVETILITGKD"
     gene            2077..2706
                     /locus_tag="PKM11_07525"
     CDS             2077..2706
                     /locus_tag="PKM11_07525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HNX48389.1"
                     /translation="MKLIALLSGGIDSPVAAHVMAERGAEMVLLHMDNRPFCSDLGVR
                     KASLLAEALRKGTGQEMPLYMAPHGENQAVNKERCQSSYQCVLCKRLMLQTAQAVARQ
                     LGASGIVMGDSLGQVASQTLNNIRAEQYGLELPVLRPLIGLDKLEIERIAKDIGTYEI
                     SIMSDGNKDCTAVPSRVITNALVKDILEEEAKVDLRSMALRSAGMAKRV"
     gene            complement(2703..2966)
                     /locus_tag="PKM11_07530"
     CDS             complement(2703..2966)
                     /locus_tag="PKM11_07530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48390.1"
                     /translation="MSQIPLEQGVIDFISQNKQDYRICTSCSGPVMLPVALKSPKSTD
                     IVIEIGENKLYISRVQARYLRKVTSDMIYDPEVGLSCNAYPGL"
     assembly_gap    3042..3141
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(3262..4068)
                     /gene="proC"
                     /locus_tag="PKM11_07535"
     CDS             complement(3262..4068)
                     /gene="proC"
                     /locus_tag="PKM11_07535"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HNX48391.1"
                     /translation="MRIGFVGAGNMAEAMMKGIISGGLAKTEDLIASEIVPERRDYIT
                     NTLGVQTVSDNIEVVRSSDVVILAVKPHHVGPVLDELKPYLSGNHLLISIAAGVKIAF
                     MESHLNWGVRVVRVMPNQPCFVGASASGFALGRSAKKEDKETVQNILNSVGVAFALDE
                     KLLDAVTGLSGSGPAYIYLVIEAMADGGVLAGLPRDVALQLAAQTVIGAGKTYLETKK
                     HPGELKDMVASPGGTTIEGLRVLEEAGVRGAFIDAVEAGAKRSEELGGKN"
     gene            4497..4856
                     /locus_tag="PKM11_07540"
     CDS             4497..4856
                     /locus_tag="PKM11_07540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="HNX48392.1"
                     /translation="MLVDDYFPVAMFALVALLIPAVAIITGKLFRPTNRAEMRDTTYE
                     CGERPIGVAQIQFHVQFYIYAIIFVAFDILTVFLIVWAMAFEGLSDIANIAAITFLVI
                     LLAGVYYSLKKERILWI"
     gene            4847..5410
                     /gene="nuoB"
                     /locus_tag="PKM11_07545"
     CDS             4847..5410
                     /gene="nuoB"
                     /locus_tag="PKM11_07545"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HNX48393.1"
                     /translation="MDIDLSFNAMTMTAKQFGEMTKTMMRETMVATGGKKVVDKITAP
                     IWSWGQRNSVYPLHFGIACCALEMAAAGGPRYDAERLGIVFRSSPRQSDVLLLNGWIS
                     AKLRPSLKALYEQMPGPKWVIAMGECTISGGPWYDAYNVIQGADTFIPVDVYIPGCPS
                     RPEAMIQAFNMLNRKLTAENRGSFLDD"
     gene            5420..5896
                     /locus_tag="PKM11_07550"
     CDS             5420..5896
                     /locus_tag="PKM11_07550"
                     /inference="COORDINATES: protein motif:HMM:TIGR01961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HNX48394.1"
                     /translation="MSQVIVYDTPDRSVEDIANDLRSKFPAVEVLKTAPKRLHVQVPR
                     DISFEVCKFMKEGLNFEHCSCVTTVDYMDHFTVVFHISSWTNHILSEVLVDLPRDDPM
                     VDSITPLWGGANWHEREAYDLMGIVFKGHPDLRRIMMPEEFKFHPLRKDFIVGRRV"
     gene            5898..6986
                     /locus_tag="PKM11_07555"
     CDS             5898..6986
                     /locus_tag="PKM11_07555"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit D"
                     /protein_id="HNX48395.1"
                     /translation="MPTDEMWINMGPQHPFNHGLWNLRVKLKGETITQAEPIIGYLHR
                     GWEKMVENRTYSQIVPLADRLCYGSSLSWNHLYCLTAEKIYGIEAPDRAKYIRVAVLE
                     LQRITSHLTWLMAVGTDLGSYTIMTWSIRERELFLDLLCKLSGARMTYNYCRIGGVRN
                     DLPENYERDVLRVLDEFEKRLRDLESLMDENTPFLMRTVGIGTMDGKTAMNLGLTGPI
                     MRASGVDMDLRKLDPYEVYADMKFEVCTHTDGDVYARYRVRMDEMRESMKIVRQALSE
                     APAGPIRVKVPRCPPKGNVVCHVEDPRGESLMYMVSDGSEKPYRLKVRSPNFVNLSAS
                     PPMLVGFKISDVPAIMGVMDMCIGETDR"
     gene            6991..8076
                     /locus_tag="PKM11_07560"
     CDS             6991..8076
                     /locus_tag="PKM11_07560"
                     /inference="COORDINATES: protein motif:HMM:NF012373.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit H"
                     /protein_id="HNX48396.1"
                     /translation="MSNLYIELTNFTEWLLGLVASILDWTKLGFLSDFGEWLQTAPVV
                     DFISTLLVAVIFLITAMMFGLCFIWQERKFLGRFMDRRGTQVGFLGFFQNFADGIKVV
                     LKEHIVPKDSDHLLFEVAIFTYLASTFMLFGCIPFSDNFYVINVNLAVLLGVAIFAFG
                     PFSILIGGWSSNNKFTLIGGMRAAAQLIAMEIPLLLCIVSVVIMTGDLSFVGVVTWQE
                     QNIWLIVPLFIGALTFFIAAIGESERIPFDLPEAEAELVEGWATEYGDVRWGLQMASD
                     YFRAYVLSGLFTMLFLGGWAGPEFIWAEAWYLGKTFVVFFFFIWVRAATVRIRTDQIL
                     KLGWRRLLPMAVINLLIAVALKVAGVF"
BASE COUNT         1738 a         2280 c         2344 g         1696 t
ORIGIN      
        1 gaagaaggtg aagtcggctt gacatcctcc cgtacggcat tggtccccca gctacccgac
       61 ctcgacaaga tcagacagat gagaaagcgc ttgaacctgt cacagcggga attggcaggc
      121 ctggccggag ttagccaatc cctgatcgcc aagatagagc ggggcaccat agatccctct
      181 tacagcaacg tacgcaagat cctcgccgcc ttcgaagagg tgataaggcg tcggaaggtg
      241 gagggcgtgc gttccggcac ccagctcacg gtcggtgatc tagccacgcg aggtgtcata
      301 ttcgttaccc cggaccagac catcggcgag gcggtggaga ggatgatgaa ggggcggttc
      361 acccaactgc cggtgatagt cggggagcgc atagttggcg gtctgaccga cgacgccatt
      421 cgggatcaca ccattgagca gaccaagacc cggaagaaga cctatgagga ggtcatgcgg
      481 accaggatcg aggagatcat ggacgccccg ttccccatat tgaacgagga cacccctatc
      541 gacctggcct cgttccacct gcagagagag gaagcgatat tggtctcccg caaaggggct
      601 atcgtaggca tcctgaccag cgccgacttc cttaacctgg gtctaaacca gtgatcgttc
      661 agtaaaccct ttacatagcg gtcggaaggt gaaatgatga agaggaggga actggagatg
      721 gtattgcagt ccctatctcc cttctcatct ccgcgtccgg agctggagca atactccacg
      781 ccggcggtca tggccgccga cctgctgttc gatgctttgg ccagaggcga tatcgaaggg
      841 cgcaaggtcc tcgatctggg atgcggcacc gggccattag gaatcggggc ggccctgctt
      901 ggcgccgatc cggtcctggg cttcgacaag gaccccaagg cgttggaagt ggcttcggcc
      961 aacgccgcca aggtcggcgt ggaaatggat cttcatcagg cggacatttc ggacgtgcag
     1021 gaaaaggcgg acacggtgat catgaaccca cccttcgggg cgcagcgcaa aggggccgac
     1081 aggccgttcc tgacggcggc catgaggtgc gccccggtca tctattcgct tcacatgagc
     1141 agcacggagg acttcgtcca gcgtttcgtt ggcagatctg gattcaccgc caccccgtta
     1201 aaaaggtata aattcgggat tccttatatg ttcgaattcc atagcaaggc gaagaaagag
     1261 atcgacgtca cgctatttta cattctaaga acaggtgtgt tggaatgagt gacaagaaaa
     1321 aggttttacc aggtgacgag gtggccgtgg ctgaggagta cctcccggcc gatggcactt
     1381 atgaggagga cgggatagtt tattccgccc tgaccggcga gctgaaggtg aacgacaggg
     1441 acaagaccgt tagcgtggag gccgagaatc ccatggtctc cctgacgatc ggcgattccg
     1501 ttttctgcga ggtgaccgac gtgcgcgcat ccatggccat atgtgaagtc gtggccgtag
     1561 agggacgttc ccgcaatatt actggagata ccaacgggac cattcacgtt tccaagatat
     1621 cttcggacta cgtccaggac gtgggccggg aatacaggcc cagcgacatc atccgggcca
     1681 aggtcatgca ggtcaggcca tccatacagc tgaacacgac ccagccgcat ttcggcgccg
     1741 tcaagtcctt gtgccgcaac tgccgctctc aattaaagaa ggcggacaag gggctgtact
     1801 gcgatcactg cgaggcgtac gaatcgcgca aggtcgctga cgactacggc ttcgtggaga
     1861 ccatcctcat caccggcaag gattgagggg gtagggctcc tgaccgaggc cgatctggca
     1921 cgtgagatcc ggaacctccg ggaggaggtc aggcagatga aggagctcat cgacctgctg
     1981 gtagcgctgg tggtggagag cgacgacatc gacgaggaag agccggggct ggaactggcc
     2041 ggcggtgcgg agatcccccg ccttaacaac tgaaccatga aacttatcgc tcttttatct
     2101 ggagggatcg actccccggt ggctgcgcac gtcatggccg aacgaggcgc ggagatggtc
     2161 ctcctccaca tggacaaccg ccccttctgc agcgatctcg gagtacggaa agcgagcctt
     2221 ctggccgagg cgctgcgcaa gggaacgggg caggagatgc ccctgtacat ggcaccgcac
     2281 ggtgagaacc aggcggtgaa caaggagagg tgccagagct cctatcaatg cgttctctgc
     2341 aagaggctga tgctgcagac cgcccaggcg gtagctaggc agctgggggc gtcagggata
     2401 gtcatgggcg attctctggg ccaggtggcc tcccagacct tgaacaacat aagggccgag
     2461 cagtatggcc tggaacttcc agtattgcga ccattgatcg gcctggacaa gctggagatc
     2521 gagcgtatcg ccaaggacat cggtacctac gagatatcca taatgagcga cggcaacaag
     2581 gactgcacgg ccgtgccatc aagggtcata accaacgcct tggtgaagga catattggag
     2641 gaggaggcca aggtggacct gaggtccatg gccctccgct ccgccgggat ggcaaaaagg
     2701 gtctagaggc ccggataggc gttgcaggat agtccgacct cagggtcgta gatcatgtcc
     2761 gaggtaacct tccgaaggta cctggcctgc actctggaga tgtagagctt gttctccccg
     2821 atctcgatga cgatatcggt ggacttgggg gatttcaacg ccaccgggag catgaccggc
     2881 ccggaacagg aggtgcagat gcggtagtcc tgcttgttct gagaaatgaa atcgatgact
     2941 ccctgctcca aaggtatctg tgacatcggg gctcgtttat caggagatgg tatttataaa
     3001 tctcgctgaa agcaccgtca tccacaaagt tatcaagggc gnnnnnnnnn nnnnnnnnnn
     3061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3121 nnnnnnnnnn nnnnnnnnnn ngggataacc aaggtggtgc gttggaacta cctctgcact
     3181 ggctgcggaa aggtgttcaa agagccgcaa ccggactgcc cgatatgcgg ctcatccctg
     3241 cgaaccacgc gccgaagatg atcagttctt cccgcccagc tcctcgctac gcttggcccc
     3301 ggcctccacg gcgtcgatga acgccccgcg aacccctgcc tcttccagga cccgaaggcc
     3361 ttcgatggtc gttccgcccg gggaggccac catgtccttc agttcgccag ggtgcttctt
     3421 cgtctccaga taggtcttcc cggccccgat gacggtctgc gccgccagct gcaacgctac
     3481 gtcccttgga agtccggcga gaacgcctcc gtcggccatc gcttcaatca ccaggtaaat
     3541 gtacgccgga ccgctcccgc tgagcccggt cacggcatcg aggagcttct catcgagggc
     3601 gaaggccacc cccacggagt tcaggatgtt ctgcaccgtc tccttgtcct ccttctttgc
     3661 cgagcggcct agggcgaacc cggaggcgga agccccgacg aaacagggct gattgggcat
     3721 gaccctcacg acccgcacgc cccagttaag atgggactcc atgaaggcta tcttgacccc
     3781 ggcggcgatg gagatcagaa gatgattgcc gctgagatac ggtttcagtt cgtccaggac
     3841 cgggccgacg tgatgtggct taacggccag gatcaccacg tccgaggagc gcacgacctc
     3901 gatgttgtcg gagacggtct gcactcccag ggtgttggtg atgtagtccc tcctctccgg
     3961 cactatctcg cttgctatca aatcctcggt cttggccagt ccgcccgata tgatgccctt
     4021 catcatggcc tcggccatgt tgcccgcccc tacgaatccg atcctcatga taacacctat
     4081 gattggatga ccttccatcg ataacttcgt attaatccga tttggtccga tccccgttca
     4141 agaccttgag aacattttgt gatgacctca gtagaggata tggtcctcgg accacggcaa
     4201 cctttctcca tgaccggtcg acgatgcttc gttagatcgg atatagagac acaaaagttc
     4261 caggttttta tctagtcctt tgcccgaccg ctatcttgtt ccgatcatcc ggtgtgataa
     4321 taagattctg ctttaggata ttaataattc atcgtccgga agtgccttaa aaggaccaaa
     4381 tattaattat tatgtcatat acaaaatata actatctggt cataccaaaa aaaacttcac
     4441 aattgaccct ctggaaatgt taaaggtata aataaaggaa gcattatccc ccttcaatgc
     4501 tcgtagacga ctatttcccg gtagcaatgt ttgctctggt ggctctactt atccccgccg
     4561 tggctattat cacggggaag ctgttcaggc cgactaatcg cgctgagatg agagacacga
     4621 cctacgagtg tggtgagagg cccatcggag tggcccaaat tcaattccac gttcaattct
     4681 acatatatgc catcatcttt gtggccttcg atatccttac ggtttttctt atcgtttggg
     4741 ctatggcctt tgaaggactc tccgacatcg ccaacatcgc ggcgataacg ttcctcgtca
     4801 tcctgctcgc tggagtctat tattctttga agaaggagag gatattgtgg atatagacct
     4861 gtcattcaac gccatgacca tgaccgccaa gcagtttggc gagatgacca agaccatgat
     4921 gagggagacc atggtggcca ccggcggaaa gaaggtcgtc gacaagatca ccgctcccat
     4981 ctggtcctgg ggtcagagga actccgtcta tcccctgcac ttcggtatcg cctgctgcgc
     5041 cctggagatg gccgccgccg gtggtccccg ttatgatgcc gaacgcctcg gcattgtttt
     5101 cagatcatcc cccagacagt ccgatgtgct gcttctcaac ggctggatat ccgccaagct
     5161 ccgaccttcc ttgaaggcat tgtacgagca gatgcctggt ccaaagtggg tcatcgctat
     5221 gggcgagtgc accatttccg gcggcccgtg gtatgacgct tataatgtga tacagggtgc
     5281 ggacaccttc attccggtgg acgtttacat ccccggatgc ccttcccgcc ccgaggccat
     5341 gatacaggcc ttcaacatgc tgaaccgaaa attgaccgct gagaaccgcg gcagcttcct
     5401 ggacgattga ggtgtaaaga tgagccaagt catagtgtac gacacgcccg accggtccgt
     5461 ggaggacatt gccaacgacc ttaggtccaa gttccctgcc gtggaggtcc tgaagaccgc
     5521 ccccaagagg ctgcacgttc aggtcccccg cgatatatct tttgaagtat gcaagttcat
     5581 gaaggagggt ctcaacttcg agcattgctc ctgcgtgacc accgtcgatt acatggacca
     5641 tttcaccgtc gtatttcaca tatcctcgtg gaccaatcac attctgtcgg aggtgctcgt
     5701 cgacctgccc agggacgatc ccatggtcga ttcgatcacc ccgctgtggg gcggagccaa
     5761 ctggcacgag agggaggcct acgacctgat gggcatcgtt ttcaaaggtc accccgacct
     5821 gcgccgcata atgatgcccg aggagttcaa gttccatccc ctgagaaagg acttcattgt
     5881 tggaaggagg gtctgagatg cctactgatg agatgtggat caacatgggt ccccaacacc
     5941 ccttcaacca cggtctgtgg aacctcaggg tcaagctgaa gggagagacc ataacccagg
     6001 ccgagccgat catcggctac ctgcaccgcg gctgggagaa gatggtggag aaccgcacct
     6061 actcccagat cgttcctctg gccgaccgtc tttgctacgg ttcgtcccta tcctggaacc
     6121 acctttactg cctcaccgct gaaaagatct acggaatcga ggcgccggac cgcgccaagt
     6181 acattcgcgt ggccgtgctg gaactgcagc gcataacctc gcacttgacg tggttgatgg
     6241 ccgtcggtac cgacctcggt agctacacca tcatgacctg gtcgatcagg gagagggagc
     6301 tcttcctgga cctgctctgc aagttgagcg gcgcccgcat gacctacaac tactgccgca
     6361 tcggtggggt ccgcaacgac ctccccgaga actatgagcg cgatgtgctc cgtgtcctgg
     6421 atgagttcga gaagcgcctg cgcgacctcg aatcgctgat ggacgagaac accccgttcc
     6481 tgatgaggac ggtcggtata ggcacgatgg acggcaagac cgccatgaac ctcggcctaa
     6541 ccggaccgat catgagggcc agcggagtgg atatggacct ccgcaagctg gacccctacg
     6601 aggtttacgc ggacatgaag ttcgaggtct gcacccacac cgatggcgat gtgtacgcca
     6661 ggtaccgggt gcgcatggac gagatgcgcg agagcatgaa gatcgtccgc caggcgttgt
     6721 ccgaggctcc cgccggccct atccgggtca aggtgcctag gtgcccgccc aaggggaacg
     6781 tggtctgcca cgtggaggac ccccgcggag agtcgctgat gtacatggtc agcgacggat
     6841 cggagaaacc gtaccgcctg aaggtgcgtt ccccgaactt cgtgaacctg tcggcctcgc
     6901 cgccgatgct ggtcggcttc aagatatccg acgtcccggc catcatgggc gtcatggaca
     6961 tgtgcatagg agaaacggac aggtgatcag atgtcgaacc tttacattga actgaccaac
     7021 ttcaccgagt ggctgctggg actggtcgcc tcgatcctcg attggaccaa gctggggttc
     7081 ctcagcgatt tcggggaatg gctgcagacc gctccggtgg tcgacttcat ttccacgctg
     7141 ctcgtagcgg tgatattcct gatcacggcc atgatgttcg ggctgtgctt catttggcaa
     7201 gagaggaagt tcctggggag gttcatggac cgccgcggta cccaggtcgg tttcctcggt
     7261 ttcttccaga acttcgccga cggtatcaag gtcgtcctga aggagcacat cgtgcccaag
     7321 gactccgacc acctgctgtt cgaggtagcg atcttcacct acctggcatc gaccttcatg
     7381 ctgttcgggt gcataccgtt ctccgataac ttctacgtca taaacgtcaa cctggccgtt
     7441 ctgctgggtg tggcgatatt cgccttcggg cctttcagca tcctgatcgg tggatggtcc
     7501 tccaacaaca agttcacctt gatcggtggt atgagggccg ccgcgcagct gatcgccatg
     7561 gagatacccc tgctgctgtg catcgtctcc gtggtcatca tgaccgggga cctgtccttc
     7621 gtaggcgtgg tcacctggca ggagcagaac atctggctca tcgtgcccct gttcataggc
     7681 gccttgacct tcttcatagc cgccatcggg gagtccgagc gtataccgtt cgaccttccg
     7741 gaagcagagg cggaactggt ggaaggatgg gctaccgagt acggtgacgt gcgatggggt
     7801 ctgcagatgg cttccgatta cttccgggcg tacgtactaa gcggactgtt caccatgctc
     7861 ttcctgggcg gatgggccgg tccggagttc atatgggccg aggcctggta cctgggcaag
     7921 acgttcgtcg tgttcttctt cttcatatgg gtccgtgcgg ccaccgtgag gatcaggacc
     7981 gaccagatac tgaagcttgg atggaggcgg ctccttccca tggccgtgat caacctgttg
     8041 atcgctgtgg cccttaaggt cgcgggggtg ttctgatgag gatagaggaa aggacgtaca
     8101 ctaaggatga ccacttccgg gccaccggtt acatattgaa gaccatgctg gtcacctt
//
LOCUS       DAOPZI010000047         7936 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_10943_length_7936_cov_10.201370, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000047 DAOPZI010000000
VERSION     DAOPZI010000047.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 7936)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 7936)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7936
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_10943_length_7936_cov_10.201370"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(187..462)
                     /locus_tag="PKM11_07565"
     CDS             complement(187..462)
                     /locus_tag="PKM11_07565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48397.1"
                     /translation="MRPHLEVHLRERTLVLPCQATEERSHCTSPFGDWLGAIVLCSCG
                     SMVRLDQATVHRRRMLGKPVECHHCRNRRVALEKEEMDSEFYGREME"
     gene            complement(770..1210)
                     /locus_tag="PKM11_07570"
     CDS             complement(770..1210)
                     /locus_tag="PKM11_07570"
                     /inference="COORDINATES: protein motif:HMM:NF013224.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HNX48398.1"
                     /translation="MLDEKDRAILSELEKDSRRSTKSIAKDLNIPRATVHERIRRMME
                     RGIIKGFTVVPDFGKLGEPVTAFILVSFLPNNNQSQRELADKISRLDGVHEVHLISGE
                     HDILLKVRGESMERIGDLVIDKIRQMDGVGRTLTCTCFATVKDE"
     gene            complement(1238..1675)
                     /locus_tag="PKM11_07575"
     CDS             complement(1238..1675)
                     /locus_tag="PKM11_07575"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF014608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HNX48399.1"
                     /translation="MQEEFITDLEMLHDYQFNISFDDQGLADIRSDEPVPIGGGEYPN
                     ATRYLSAAVGNCLCASLAFCLRKARSEPISMKARVRTVLGRNDKGRLRVQSMQVTIFP
                     EVDDQAKLERCLPLFEDFCTVSAAVREGIDIQVSVETPKSEQR"
     gene            complement(1685..2869)
                     /locus_tag="PKM11_07580"
     CDS             complement(1685..2869)
                     /locus_tag="PKM11_07580"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HNX48400.1"
                     /translation="MGRFFSAEHDDIHKGLTTDVYFQRTEAILKAKGLLGTDTRSEFT
                     VASLPDAWPWAVLCGTEEMVRILEGRNIDLYGLPEGSVFTSRTKKGIKLPVAAIDGPY
                     GEYCSLETPALGFMCYASGVATMSARCKKAAAGLPVISFGVRRMHPAMAPVIDRSSYI
                     GGCDGVSSLKGAELVGRPASGTMPHALVIMMGDQREAFRAYGEIIDPNVPRVALTDTF
                     FDEKVEALMAAEEMPGLRSVRLDTPGSRRGNMADIVREVRWELDLHGHKNVGVFVSGG
                     LDEVKVKELAAAGVSGFGVGTSISNAPTIDFAMDIVEKGGVPIAKRGKFAGRKFVFRC
                     PECLEYEVSLDRNHPPVCSCGKEMRWAEVKIIEKGKRLVPEEPAEEIRRRVLKQLDRI
                     DI"
     gene            complement(2919..4190)
                     /gene="eno"
                     /locus_tag="PKM11_07585"
     CDS             complement(2919..4190)
                     /gene="eno"
                     /locus_tag="PKM11_07585"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HNX48401.1"
                     /translation="MSELTITRVWGREVLDSRGNPTVEAQVETDAVIVTAIAPSGAST
                     GTFEALELRDGDSRYGCKGVQKAVRNVRDLISPRLKGMDVSDLRSIDAAMIELDGTEN
                     MGRLGGNATTAVSYAAAKAGAILKGVELHEHLGSKSKVLPVPSMNVINGGKHAGSNLK
                     IQEFMIVPCGMPSFSEALRAGVEVYHNLKTVLKKEMGPMSINVGDEGGFAPSFDTSRQ
                     AMDVLIKAIEAAGYQPGKEVYLAMDAAASEFYSKGVYTLDGKKMGTGEIVDFYSKVAQ
                     EYPLISLEDPVHEEGFEDMVELTRKLGKKLQIMGDDMFVTNPVRLRKGIEMGAGNAML
                     LKVNQIGTITKAMQAAEICFDRGYNVQVSHRSGESEDTTMADIAVALECGQIKSGAPA
                     RTERTAKYNRLLRIEENLGSKAKFMGRGAFF"
     gene            complement(4209..5150)
                     /locus_tag="PKM11_07590"
     CDS             complement(4209..5150)
                     /locus_tag="PKM11_07590"
                     /inference="COORDINATES: protein motif:HMM:NF017570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF835 domain-containing protein"
                     /protein_id="HNX48402.1"
                     /translation="MDDNTAILEIVSELISAAGYQPMIATGGRECLTKIQLESPDLVL
                     LDINMPDMDGWTVLRTLKEKGLAENTKIIMLTATTEIGSDIFGLQDVVSGYIRKPFNN
                     DELGARFRDMLGDTPQIKEEPRTDKDRKGLRSLLRKKEEESGMEVARSSAKVYELRRG
                     FSYLVKETKPNKSFEMFVDQVTHNIQGLCVTRQHPTIIRKEWGLEKTPIIWLSNQLGK
                     VYVNPSNIGILSDTIIRFVEKSGDGIILIDGIEFLIVNNDFDKVLRMVHHVTEAVMEN
                     RARLIVSIDPRTLETRELALLERNMEIIEAEETKPHQ"
     gene            complement(5283..5432)
                     /locus_tag="PKM11_07595"
     CDS             complement(5283..5432)
                     /locus_tag="PKM11_07595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L40e"
                     /protein_id="HNX48403.1"
                     /translation="MARFKEADERLLNKKVCLSCYARNAVKATRCRKCGYTSLRLKAK
                     ESRKA"
     gene            complement(5485..6438)
                     /locus_tag="PKM11_07600"
     CDS             complement(5485..6438)
                     /locus_tag="PKM11_07600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication factor C small subunit"
                     /protein_id="HNX48404.1"
                     /translation="MQEIWTEKYRPQKLSDVVGQRDIVERLSSYVRSKNLPHLMFAGP
                     AGVGKTTSALAMAKEMYGETWRNNFIELNASDERGIDVVRGKIKEFARTAPLGGADFK
                     IIFLDEADALTQDAQAALRRTMERFSRNCRFVLSCNYSSKIIEPIQSRCAIFRFRPVK
                     AEDIKHHLQVVAKKEGVKIDDAALDAIVHVGEGDMRKSINSLQVAATIGKDVTIDVVY
                     QATGNARPDEVVDMVNTALAGDFSGARTKLDEMMITYGLSGEDIIKQIHRSFYDLDIP
                     DREKIRLIDRTGEIEFRIVEGSNERIQLEALLAYLALVEKD"
     gene            6541..7455
                     /locus_tag="PKM11_07605"
     CDS             6541..7455
                     /locus_tag="PKM11_07605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00269 family protein"
                     /protein_id="HNX48405.1"
                     /translation="MRCFKCSAPAVTYIRYNGTHLCRSHLLEFVERRVKKEVRSQLKL
                     EGDVHIAVGASGGKDSQTALFLMHKILGCRKNVKLTAITVDEGVAGYREQTIPKVQEL
                     CKGLDIEHVMVTFDEVADLDLDGMVRRTDESEACTYCGVFRRRCLNLKAKEIGVDHLA
                     LGHNLDDMAQSILMNFMRGDVERLARLGPHERVQPGLVPRMQPLRVIPEKETLLYAML
                     SELPFSDAECPYAKHAMRNEYRNIVDEMENRHPGTRHSILGSYDRLRPLMRDGFPQSA
                     LRACACGEPTLNERCKACEMLEKMRKGF"
     gene            complement(7471..>7936)
                     /locus_tag="PKM11_07610"
     CDS             complement(7471..>7936)
                     /locus_tag="PKM11_07610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HNX48406.1"
                     /translation="AEWEIYGEKYAAQVCKNAKALGQALHELGIEVLCSHKGFTESHT
                     IAVNVAPYGGGAEAANLMEKANMIANKNMLPGDKSSVKPSGIRLGAQEMTRVGMRESE
                     MKEVASLIHRVVVKKESPEVVKKDTMALKRNFTKVRYCLHEGEEAYAYHKLV"
BASE COUNT         1496 a         2435 c         2221 g         1784 t
ORIGIN      
        1 gcgcgatctt ctttccggtg ctcccggata tcttgtccac gctgttcagg atcaaggtgg
       61 tcttcccact gcccaggaaa ccggcgacta ttatcatgtc catatgctaa cctcaggata
      121 ggaaaattca atccagggcg gggtataaga aacttgcccg ttgaacacac aggccacgga
      181 aagggttcac tccatctcgc gaccgtagaa ctcggagtcc atctcttcct tctccaaggc
      241 cacccgccgg tttcggcagt gatgacattc caccggcttg cctagcatcc ggcggcgatg
      301 caccgtcgcc tggtccagac gtaccatgga accgcaggag cacaggacta tggcgccaag
      361 ccagtctccg aacggggagg tgcaatgact gcgctcctcg gtggcctggc aggggagcac
      421 cagcgtcctt tcccttaggt gcacctccag gtgaggacgc atctcctcac catctgacct
      481 gagcgtagct tgcgctaatt gatcattaag caataaactc attcctattc agagcatgct
      541 gccccctcta ccagcagccc acaagttact ggacggaaga cgtgacccct cgcaataatc
      601 tgaacaaaaa agcctaaggc tctgagatat tttaaagatt tccttaacgt cctatacgtt
      661 tttttatgct gtccagtact ataaagtgca acctggtttt ttcatataag aacgattgtc
      721 ggtcgctacc gaaaatgagc gtccctaccc tattatgata gagatgggtt cactcgtcct
      781 tgaccgtggc gaagcaggtg caggtgaggg tacgcccgac gccgtccatc tgccggatct
      841 tatcgatgac caggtcaccg atgcgctcca tggactcccc gcgcaccttc aagagaatgt
      901 catgctcgcc ggagatcaga tggacctcgt gcacgccgtc cagacggctt atcttatcgg
      961 ccagctccct ttgggactgg ttgttgttcg gtaagaagga gaccagaatg aaggcggtga
     1021 ccggctctcc caactttcca aagtccggaa cgacggtgaa ccctttgatt attccgcgct
     1081 ccatcatgcg gcggatgcgc tcgtgaacgg tggcccgggg tatgttgagg tccttggcga
     1141 tggacttggt gctgcgcctg gaatccttct ccagctcgct cagtatggcc cggtcctttt
     1201 catcgagcat cagtggtggg aatgcccttc cgctagatta tctttgctca cttttagggg
     1261 tttccaccga cacttggata tcgatccctt cgcgcactgc ggcgctcacc gtgcagaagt
     1321 cctcgaacag gggaaggcat ctttccaact tcgcctggtc gtccacttcc gggaatatcg
     1381 ttacttgcat gctctgaact cgcagacggc ccttgtcgtt gcggcccagc acggtgcgca
     1441 cgcgggcctt catggatatc ggctcggacc gcgccttgcg tagacagaat gcgagagagg
     1501 cacacaggca gttgcctacg gccgcggaaa gatagcgtgt cgcgttgggg tattccccgc
     1561 ccccgatcgg tactggctcg tcggaacgta tgtccgccag gccttgatcg tcgaagctta
     1621 tgttgaactg atagtcgtgc aacatctcca gatcggtgat gaactcctct tgcatgtatg
     1681 cacctcagat atcgatcctg tccaattgct tgaggacgcg gcggcgtatc tcctccgcag
     1741 gctcctcggg caccaggcgt ttccccttct cgattatctt gacctccgcc cagcgcatct
     1801 ccttaccaca agagcatacc gggggatggt tccggtccag tgatacctcg tactccaggc
     1861 attcggggca gcggaacacg aacttgcgcc cggcgaactt gccgcgtttg gctattggca
     1921 ccccgccttt ctccacgatg tccatggcga agtcgatggt gggggcgttg cttatcgacg
     1981 tcccaactcc gaagccgctc accccagcgg cggccagctc cttcaccttc acttcatcca
     2041 gaccgccgga gacgaatacg cccacgttct tgtgaccgtg caggtccagc tcccagcgca
     2101 cctcccggac gatgtcggcc atgttgccgc ggcgtgaacc cggagtatcg aggcgtaccg
     2161 agcgcagccc gggcatctcc tcggcggcca tgagcgcttc gaccttctcg tcaaagaacg
     2221 tgtccgtgag tgcgacccga ggaacgttgg gatcgattat ctccccgtaa gctcggaaag
     2281 cctccctctg atcgcccatc atgatgacca gggcatgcgg catggtaccg ctggccgggc
     2341 gaccgaccag ttccgcccct ttcagcgacg agacgccgtc gcaaccgcct atgtaggacg
     2401 atcgatcgat gaccggggcc atggccgggt gcatgcgcct caccccgaac gatatcaccg
     2461 gcagaccggc ggccgccttc ttgcagcggg cggacatggt ggccacgccg ctcgcgtagc
     2521 acatgaaccc cagcgccggg gtctccaggg agcaatattc gccatacggc ccgtcgatgg
     2581 ccgccaccgg aagcttgatg cccttcttgg tccgggaggt gaacacgctg ccctccggca
     2641 gaccgtaaag atcgatgttc ctgccttcca ggatacgcac catctcctcg gtgccgcaga
     2701 gcaccgccca cggccaggca tcgggtaggg aggccaccgt gaactcggaa cgggtgtcgg
     2761 tgcccaggag acctttggcc ttgagtatgg cctcggttcg ctggaagtat acatcggtcg
     2821 tcagaccctt gtggatatca tcgtgctcgg cggagaagaa cctgcccatg tcatcacctg
     2881 aaccttacgt catcgagttc cgacagcatg aaccttcttc agaagaaggc cccgcgcccc
     2941 atgaacttgg ccttgctccc caggttctcc tcgatgcgca gcagccggtt gtacttggcc
     3001 gtgcgctccg tgcgagccgg agccccgctc ttgatctgac cgcattccag ggccacagcg
     3061 atgtcggcca tggtggtgtc ctcggactcc ccggagcggt ggctcacctg gacgttgtat
     3121 ccgcgatcga agcatatctc cgctgcctgc atggccttgg ttatcgtccc gatctggttg
     3181 accttcagga gcatggcgtt ccccgccccc atttcgattc ccttccttag acggaccggg
     3241 ttggtgacga acatgtcatc gcccatgatc tggagcttct tccctaattt ccgggtgagc
     3301 tccaccatgt cctcgaaccc ttcctcgtgc accgggtcct ccagactgat cagaggatat
     3361 tcctgcgcca ccttggaata gaaatccacg atctcgccgg ttcccatctt ttttccgtcc
     3421 agcgtgtaaa cacctttgga atagaactca ctggccgcgg catccatcgc caggtagacc
     3481 tcctttcccg gctggtaacc ggcagcctct atggccttga tcagaacatc catcgcctgt
     3541 cggctggtgt cgaaggacgg cgcgaatccg ccctcgtcgc ccacgttgat ggacatgggg
     3601 cccatctcct tcttgaggac cgtcttgagg ttatggtaga cctctacccc cgcccgcagc
     3661 gcctcggaga agctgggcat gccgcagggc actatcatga actcctggat cttgagattg
     3721 ctgccggcgt gctttccgcc gttgatgacg ttcatggacg gcaccgggag caccttgctc
     3781 ttggaaccga gatgctcgtg aagctccacg cccttcagga tcgccccggc cttggccgcg
     3841 gcgtaggata cggcggtggt ggcgttcccg cccagtcggc ccatgttctc cgtgccgtcc
     3901 agttcgatca tcgccgcgtc tatggacctg aggtcgctga cgtccattcc cttcaagcgg
     3961 ggggatatca ggtcgcggac attgcgcacc gccttctgga cgcccttgca gccgtacctg
     4021 gagtcgccgt ccctcagctc caacgcttcg aaggtcccgg tggacgcccc ggaaggcgca
     4081 atggcggtga cgatcacggc gtccgtctcc acctgggcct ccacggtggg atttccccgg
     4141 gaatccaaga cctctctgcc ccaaaccctg gtaatggtta gttctgacat tttctcaatc
     4201 tccgatagtc attgatgagg tttcgtctcc tcggcctcga tgatctccat gttgcgctcc
     4261 aggagcgcca gttccctggt ctctagcgtg cgcggatcga tggacacgat caaacgggcc
     4321 cggttctcca tcaccgcctc ggtgacgtga tggaccattc tcagcacctt gtcgaaatcg
     4381 ttgttcacga tcaggaactc gataccgtcg atgaggatga tgccgtcccc gctcttctcc
     4441 acgaagcgga tgatggtatc gctcaggata ccaatgttgg acggattgac atacaccttt
     4501 cccagctgat tgctcagcca gatgatggga gtcttctcca gtccccactc cttgcggatg
     4561 atggtgggat gctggcgggt gacgcacagc ccctggatgt tgtgggtgac ctggtcgacg
     4621 aacatctcga aggacttgtt cggtttcgtt tccttgacca gatagctgaa tccccgacgc
     4681 agctcgtaga ccttggcgct gctgcgagcc acttccatac cgctctcctc ctccttcttg
     4741 cgaagcaggg aacgcagccc tttgcggtcc ttatccgttc ttggctcctc tttgatctgc
     4801 ggcgtatcgc ctagcatatc tctgaaacga gcgccaagct catcgttgtt gaaaggtttt
     4861 cgaatataac cggacaccac atcctgcagc ccgaatatgt ccgagccgat ctcggtggtg
     4921 gcggtgagca tgattatctt cgtattctcg gccagtccct tctccttgag ggtgcggagc
     4981 acggtccaac cgtccatgtc cggcatgttt atgtccaata ggaccaggtc cggactttcc
     5041 agctgtatct tggtcaggca ctcccgaccc ccggtagcga tcatgggctg gtaacccgcg
     5101 gcggagatca gttcggagac gatctccagg attgcggtgt tgtcgtccac gaccaaaatc
     5161 ttcttgatca gaattccccc agcgctaagg acgttgggtc atatgctcag gtgattaaaa
     5221 atcctatccc ctggattctg tctggggata atgaatgtga agaagaggtt tgagattctg
     5281 gtttaagcct tgcggctctc tttggccttc aggcgcagcg aggtgtaacc gcacttgcgg
     5341 cacctggtgg cctttacggc gttacgggca tagcagctaa ggcatacctt cttgttcagt
     5401 agcctttcgt cagcttcctt gaaacgtgcc atttgactcc tccgcccttg aaatatggag
     5461 ccgatataaa aaggttggct atgttcagtc cttctcgacc agcgccaggt aggccaggag
     5521 cgcctccaat tggattcgct cgttacttcc ctccacgatg cggaactcga tctcgccggt
     5581 ccggtcgatg agccgtatct tctcccggtc cgggatgtcc aggtcgtaga aggagcggtg
     5641 tatctgcttt atgatgtcct ccccgctcag accataggtt atcatcatct cgtccagctt
     5701 cgtccgggcg ccggagaagt caccggcaag cgcagtgttc accatgtcga ccacctcgtc
     5761 cggtcgggcg ttcccggtgg cctggtagac cacgtcgatg gtgacgtcct tgcctatcgt
     5821 ggcggccacc tgcaaggagt tgatcgattt gcgcatgtcc ccctcgccca cgtggacgat
     5881 ggcgtccaag gccgcgtcgt cgatcttaac tccctccttc ttagcaacga cctggaggtg
     5941 gtgctttatg tcctcggcct tgaccggtcg gaagcggaat atggcgcacc gggactggat
     6001 gggctcgatg atcttggacg aatagttgca ggagagcacg aagcggcagt tccggctgaa
     6061 cctctccatc gttcggcgca gagcggcctg ggcatcctga gttaaagcgt cagcctcgtc
     6121 caggaatatg atcttgaaat ctgctccccc caggggagcg gttcgggcga actccttgat
     6181 cttgccgcgg accacgtcta tgcccctctc gtcagaagcg ttcagctcga tgaagttgtt
     6241 ccgccaggtc tccccgtaca tctccttggc catggccaag gcggatgtgg tcttgccgac
     6301 gccggccgga ccggcgaaca tcaggtgtgg caggttcttt gaccgaacgt aggaggacag
     6361 cctctccact atatccctct ggcccacgac gtccgataac ttctgcggac gatacttctc
     6421 ggtccaaatc tcctgcatgt tctccggcca cttcaaagag gtatggtagt taaaaggttt
     6481 cctggagacc gccgaatgtg cggcctaaca tttattaccc cgcccggcgt gggctgaccg
     6541 atgcgctgct tcaagtgctc cgctccggcc gtgacgtaca tccgctacaa cggaacgcac
     6601 ctctgccgct cgcaccttct tgagttcgtg gagaggaggg tgaagaagga ggtccgctcc
     6661 cagctgaagc tggaagggga cgtgcacata gccgtcgggg cgtctggcgg caaggacagc
     6721 cagaccgcct tgttccttat gcacaagata ttaggctgcc ggaagaacgt gaagctgacc
     6781 gccatcaccg tggacgaggg cgtcgcggga taccgagaac aaacgatacc taaggtccaa
     6841 gagctctgta aaggcctgga catcgaacat gtgatggtga ccttcgatga agtggcggac
     6901 ctggacctgg acggcatggt ccgccggacg gatgagagcg aagcgtgcac ctattgcggg
     6961 gtcttccggc gccgttgtct gaacctcaag gccaaggaga tcggcgtcga ccatctggca
     7021 ttgggacaca acctggacga tatggcccag tcgatactga tgaacttcat gcgcggtgac
     7081 gtcgaacgat tggcgcgcct cgggcctcac gaacgggtgc aaccgggact tgtaccgcgc
     7141 atgcagccat tacgcgtcat accggagaag gagacgcttc tgtacgccat gctctccgag
     7201 ctaccgttct ccgacgcgga atgcccgtat gccaagcacg ccatgcgcaa tgagtaccgc
     7261 aacatcgtgg acgagatgga gaacaggcac ccgggcacca ggcattccat actaggcagt
     7321 tacgaccgtt tgaggccttt gatgagggac ggttttcctc agtccgcgct cagggcctgc
     7381 gcgtgcggcg agcccacgct taacgaaaga tgcaaggcct gcgagatgct ggaaaagatg
     7441 agaaagggat tttgaagagg ttttagacgc tcagaccagc ttgtggtagg cgtacgcttc
     7501 ctcgccctcg tgcaggcagt agcgcacctt ggtgaagttg cgcttgaggg ccatggtatc
     7561 cttcttgacc acttcgggcg attccttctt gaccaccacg cggtgtatga gggaggccac
     7621 ctccttcatc tcgctctccc tcatgcccac tcgggtcatc tcctgcgccc ccagacgaat
     7681 accggaaggc ttcacggagg acttgtcccc ggggagcatg ttcttgttgg cgatcatgtt
     7741 ggccttctcc atgaggttgg ccgcctcggc tccgccgccg tagggggcga cattgaccgc
     7801 gatggtgtgg ctctcggtga agcccttgtg ggagcagagc acctcgatgc ccagctcatg
     7861 caatgcctga ccgagcgctt tggcgttctt gcagacctgg gcggcgtact tctctccgta
     7921 tatctcccac tcggcc
//
LOCUS       DAOPZI010000048         6671 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_14035_length_6671_cov_8.432588, whole genome shotgun sequence.
ACCESSION   DAOPZI010000048 DAOPZI010000000
VERSION     DAOPZI010000048.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 6671)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 6671)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6671
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_14035_length_6671_cov_8.432588"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..383)
                     /locus_tag="PKM11_07615"
     CDS             complement(<1..383)
                     /locus_tag="PKM11_07615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I tRNA ligase family protein"
                     /protein_id="HNX48407.1"
                     /translation="MAQYEAITTERKWQKQWKDWELYKFDQDSDAPVYSVDNPPRYAS
                     GSLHLGHATGYSLIDFAARYHRQRGFNVMFPLCFDVNGTPVEVRVEKKYGINKYSLPR
                     QEYIRLCEEYANSFIESMKEQFEILG"
     gene            complement(432..1634)
                     /locus_tag="PKM11_07620"
     CDS             complement(432..1634)
                     /locus_tag="PKM11_07620"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX48408.1"
                     /translation="MVGESIEGMKKRELLRSLIDANKVGDLMRKKFETVDPETALSDV
                     VSKMKSSDLHEIPVVDGKKLVGVISYGAVIRKKNLVIGTKAKTMVETTPEINIDTPLT
                     EVAEHFLSTGYRQLPVTKGKALLGIVTRANVISVLPKLKEIKALKIADVMSDSARSIH
                     EKDLIKNAMSLMRDLEVRTVPVVDDQDRLVGIIGIRDIVQYSWTGPGTQAMGRQDKGG
                     NNNPVEMEVRSLMHDSPITMTAEDDLTKAINTMVEKNISTIPVVSGDRMVGIVTKYDI
                     LELVASVRNRDMVYTQISGLDEEDRFSLEIMEKEMQSGLVKISKFTRPLLFTIHVSKY
                     NNTGNRAKYSLIGRLSTENSHFMTKAVDWSLGQATVELMNNLDRIVKDKKEHNLDVRM
                     KKNLHKKV"
     gene            complement(1668..3356)
                     /gene="glyS"
                     /locus_tag="PKM11_07625"
     CDS             complement(1668..3356)
                     /gene="glyS"
                     /locus_tag="PKM11_07625"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009345 - glycine-tRNA ligase complex
                     [Evidence IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="HNX48409.1"
                     /translation="MKEVSSGEMLSLCKRRGFIYPAYEIYGGIAGLYDYGPLGTALKS
                     NIADLWRKIYALQEGFVEIDGDNVGPEAVFKASGHVDNFADLSVTCKSCGESFRADHL
                     AKGLHPNPDSLSKEELQKVLRDNDVRCPCGGEFADVEEFNLMFKTKIGPGGGRTGYLR
                     PETAQSIFVNYTNLYRHCRDKLPFGCIQVGRGFRNEISPRQGVIRLREFNMMEAELFV
                     DPEDKSWPRYQDAKDKVVRLVPNTDEKEVEMTIGEAVENGTIGNQTLGYFIWVTYDFL
                     TSAGIDPAKLRFRQHLKTEMAHYAADCWDAETLISFGWTEIVGIADRGCWDLSQHMKF
                     SKADLTAFKRFDEPRDVERDVVKPKFGALGPRFKGAAGDIKKQLEGMDASAVHDGLVT
                     VTIDGQPVDLDGMYFEVVRVKEKVNGVRVVPHVIEPSHGLDRILYSCLEHAYSEKEDG
                     YVTLKLRPAVAPIKVGVFPLMAKDGMEVVAKALDLALREEGMVTYYDDSGSIGRRYAR
                     MDEAGTPWCVTVDYDTLEKGDVTIRDRDTSEQTRISADDVVDFIKDKLKRKLSC"
     gene            complement(3363..4214)
                     /locus_tag="PKM11_07630"
     CDS             complement(3363..4214)
                     /locus_tag="PKM11_07630"
                     /inference="COORDINATES: protein motif:HMM:NF012780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HNX48410.1"
                     /translation="MPTTVGDVMTSNPIVAQVPGSRQEVLKIMVQHNLTGLPVVRRSD
                     GSLAGMITRQDIFDRPDEEQAALIMQREHPSISPKATVEEAAKILVEGTMRHLPVVEG
                     KRLVGILTPTDLLCIVEKRNIDLPVEKVIRSPCVPIFQESTLAVANVILRVSKSSALP
                     VLDEQGKLTGIITDRDIFNKAYLDGADAAAALGFGDDENHWSWDGLSNVMKLWYEVSK
                     VELPGMLIKELMVHDPTTVFKKTAISEAARIMRKNDFGQLPVRDNKDRLLAMIYDHDI
                     ISVLVKE"
     gene            complement(4215..4658)
                     /locus_tag="PKM11_07635"
     CDS             complement(4215..4658)
                     /locus_tag="PKM11_07635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032559 - adenyl ribonucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HNX48411.1"
                     /translation="MTLFKKILIPTDGSEYTKAAVTKGLEMAKATGAEVTALYVVDQT
                     SFINFPMDSTIVSVYTLLEKEGEEAMDYVKKEAEALGVKLTTRIEEGSPSRKIVDLSA
                     EHDLVVMGTLGRTGFSKLLLGSVAERVVRFAKCPVLVVRATGEEN"
     gene            complement(4663..>5028)
                     /locus_tag="PKM11_07640"
     CDS             complement(4663..>5028)
                     /locus_tag="PKM11_07640"
                     /inference="COORDINATES: protein motif:HMM:NF014081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HNX48412.1"
                     /translation="CPRSNLFFGKTPPLARMLDSGLIVALGTDNAMICLPDMLAEMEV
                     AARLLRSQGRNGAKDALDMAMNGRKLLNRQEPLSIEPGARCELMVLRQRGGDPVSDLV
                     LRSASDAPELVCIGKNCWR"
     assembly_gap    5029..5128
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<5129..5601)
                     /locus_tag="PKM11_07645"
     CDS             complement(<5129..5601)
                     /locus_tag="PKM11_07645"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminase"
                     /protein_id="HNX48413.1"
                     /translation="MRYLSGLVLGQNGFFPGHVGIEDGVIAEIGRGKKGNAHARGLIV
                     PTFVNGHTHIADYIVPVDPAISLEELVAPPKGLKHRILEQASPDDIMRGMLTMKRFMA
                     RRGVSHFLDFREGGYDGSDYLRRLDGEGADSIIMGRPKLLEFCRSGARRLLKVADG"
     gene            5689..>6671
                     /locus_tag="PKM11_07650"
     CDS             5689..>6671
                     /locus_tag="PKM11_07650"
                     /inference="COORDINATES: protein motif:HMM:NF013188.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HNX48414.1"
                     /translation="MNDLLALAFLMFLAVSAQLIASRFGLSAAIFEILLGLAVGQVLG
                     LRSLEIEWFSFLAVLGGIGLTFLAGTEMEVERVRSQWKSSLPLALASFLSIFITVPFA
                     LHYLGGWSWDSSLLAGIALSETSVAIVYVVLVEGGRARTDTGSVILAACFLTNLIASI
                     ALAVLFAPPGSEVLLLILAGLLLVPLAYRYTGKVLDRFKGRPGEPEIKLVLLPLLLLA
                     GLASMAGVAAVLPAYLLGFAMSRSLNERREAWSKVRTVFLGFMVSLFFLAAGSNVSME
                     ALLVGAAIIIALGFGRVVLKMLFVLPTVSVSLRQDRVYIALLMSTSLTFGMV"
BASE COUNT         1160 a         2040 c         1864 g         1507 t
ORIGIN      
        1 cccagtatct cgaactgctc cttcatcgac tctatgaacg agttggcgta ctcctcgcac
       61 aacctgatgt actcctgccg gggcagggag tacttgttga tgccgtactt cttttccact
      121 ctaacttcga ccggcgttcc gttgacgtcg aagcacaggg ggaacatcac gttgaagccc
      181 cgctgccggt ggtagcgggc ggcgaaatcg atcagcgagt agccagtggc gtgccccaga
      241 tgcagggagc cggaggcgta cctcggaggg ttgtcaacgg aatagaccgg cgcgtccgaa
      301 tcctgatcga acttgtaaag ctcccagtcc ttccactgct tctgccactt cctttcggtc
      361 gttatagcct cgtattgcgc catggactgg aaagggaatg ggaagtggtt taaaaaaggt
      421 tgctgagcgc ctcagacctt tttatgcagg ttcttcttca tccgcacgtc caggttatgc
      481 tccttcttgt ccttgacgat gcggtccagg ttgttcatca gttcgaccgt cgcctggccc
      541 agcgaccaat cgaccgcctt ggtcatgaag tgcgagttct ccgtgctcag ccggccgatc
      601 agggagtact tggcgcggtt cccggtgttg ttgtacttgc tcacatggat ggtgaacagc
      661 agcggccggg tgaacttgga tatcttgacc aggccggact gcatctcctt ctccatgatt
      721 tccagggaga agcggtcctc ctcgtccagt ccggagatct gggtgtagac catgtccctg
      781 ttccgtacgg acgccaccag ctccaggata tcgtacttgg ttactattcc gaccatgcgg
      841 tcgccggaga ccacgggtat ggtggagatg ttcttctcga ccatggtgtt gatcgctttc
      901 gtaagatcgt cctcggcggt catggttatc ggcgagtcat gcattaacga acgaacctcc
      961 atctccaccg ggttgttgtt cccgcccttg tcctggcgtc ccatggcctg ggtcccgggg
     1021 ccggtccagg agtactgcac gatgtccctg atgccgatga tgccgaccag tcggtcctgg
     1081 tcatccacga ccggaacggt ccgtacctcc aggtcgcgca tcaggctcat ggcgttcttg
     1141 atgaggtcct tctcgtgtat cgagcgcgcg ctgtcgctca tcacgtcagc tatcttgagc
     1201 gccttgatct ccttcagctt cggaaggacg gatatgacgt tggcgcgggt cactatgccc
     1261 aggagggcct ttcccttggt caccggcagt tgccggtaac cggtggagag gaagtgctcg
     1321 gcgacctcgg tcaggggagt gtcgatgttg atctctggag tggtctccac catcgtcttg
     1381 gccttggtac cgatgaccag gttcttctta cggatcacgg cgccgtagct gatcaccccg
     1441 accagcttct tgccgtcgac caccggtatc tcgtgcaggt cggacgactt catctttgac
     1501 acaacgtcgg agagagcggt ctccgggtca acggtctcga actttttcct catcaggtcg
     1561 ccaaccttgt tggcgtcaat cagggacctg agcagttccc tcttcttcat tccctcgatg
     1621 ctttctccaa ccattttagc tcaccttcgt agtactgtag ggtttgttca gcaagatagt
     1681 ttgcgtttga gcttgtcctt gatgaaatca acgacgtcgt ccgccgatat ccgggtctgc
     1741 tctgacgtgt cccggtcgcg tatcgttacg tcccccttct ccaacgtatc gtaatcgacc
     1801 gtcacgcacc acggcgtgcc ggcctcgtcc attctggcgt accgccgtcc gatggaaccc
     1861 gagtcgtcgt agtaggtcac catgccctcc tcgcgcaatg ccaggtccag ggccttggcc
     1921 accacttcca tgccgtcctt ggccataaga gggaacacgc ccacctttat cggggccacg
     1981 gccggtctca acttgagcgt cacgtagccg tcctccttct cggaataggc atgctccagg
     2041 cagctgtaca ggatgcggtc caggccgtgc gacggctcga tgacgtgcgg tacgacccgg
     2101 acgccgttca ccttctcctt gacccgtacc acctcaaaat acattccatc gagatctaca
     2161 ggctggccgt cgatggtgac cgtcaccagt ccatcatgaa cggccgaggc gtccattccc
     2221 tccagctgct tcttgatgtc tcccgccgca cctttgaagc gcgggcctag ggcgccgaac
     2281 ttaggcttta ccacgtcgcg ctccacgtcc cgaggctcgt cgaagcgctt gaacgccgtg
     2341 aggtcggcct tggagaactt catgtgctgc gataggtccc aacaaccgcg gtccgcgata
     2401 ccgactatct cggtccagcc gaagctgatg agcgtctcgg catcccagca gtcggcggcg
     2461 taatgcgcca tctcggtctt gagatgctgg cggaagcgca gcttcgccgg atcgataccg
     2521 gcggaagtga ggaagtcgta ggtcacccag atgaagtagc cgagcgtctg gttgccgatg
     2581 gtaccgttct ccaccgcctc accgatggtc atctccactt ccttctcatc agtgttcggc
     2641 accagtcgga cgaccttgtc cttggcgtcc tggtagcggg gccacgattt gtcctcggga
     2701 tcgacgaaca gctccgcctc catcatgttg aactcgcgaa gccggatcac gccctgacgg
     2761 ggcgatatct cattgcggaa ccctcgacca acttggatgc agccgaacgg aagcttgtcg
     2821 cggcagtgac gatacagatt ggtatagttc acgaatatgg actgggccgt ctccggacgc
     2881 aagtaaccgg tacgcccgcc gcctggcccg atcttggtct tgaacattaa attaaattct
     2941 tccacgtccg cgaactcgcc gccgcatggg caccgcacgt cattgtcgcg gagcaccttc
     3001 tgcagctcct ccttggaaag cgaatccggg ttaggatgca atccctttgc cagatggtcc
     3061 gcccggaacg attcgccgca tgacttgcac gtaacggaaa gatcggcgaa gttgtccacg
     3121 tgcccggagg ctttgaacac cgcttccggt cccacgttgt cgccgtctat ctccacgaac
     3181 ccttcctgga gcgcgtagat cttgcgccac aggtcggcga tgttgctttt cagcgctgtc
     3241 cctaggggac cgtaatcgta aagcccggcg atcccgccgt atatctcgta cgcggggtag
     3301 atgaacccgc gtctcttgca tagggagagc atctccccgg agctgacctc cttcattatc
     3361 gtctactcct tcactagcac ggagatgata tcgtgatcgt atatcatggc cagtaggcga
     3421 tccttgttat cgcggaccgg caattggccg aagtcgttct tgcgcattat gcgggccgcc
     3481 tcggagatgg cggtcttctt gaacacggtg gtcgggtcgt ggaccatgag ctccttgatc
     3541 agcatccccg gaagctcgac cttcgacacc tcgtaccaca gcttcatgac gttgctcagg
     3601 ccgtcccagg accagtggtt ctcgtcatcc ccgaagccca gggcggcggc cgcatcggca
     3661 ccgtccagat aggccttgtt gaagatgtcc ctatcggtaa ttataccggt cagctttcct
     3721 tgctcgtcca gtaccggcaa cgcggatgat ttggatactc tgagaattac gttggccacg
     3781 gccaaggtgg actcctggaa tatcgggacg caaggagaac ggatcacctt ctccacaggc
     3841 aggtcgatgt tcctcttctc cacgatgcac aggaggtccg tgggagtcaa tattcccacc
     3901 aggcgcttcc cctcgaccac gggcaggtgg cgcatcgtcc cttcgaccag gatcttcgcc
     3961 gcctcctcca cggtagcttt gggcgagatg gagggatgct ccctctgcat gatgagggcg
     4021 gcctgctcct cgtccggccg atcgaagatg tcctggcggg ttatcatgcc cgccagggaa
     4081 ccgtcgctgc ggcgcaccac cggaagaccg gtgaggttat gctgcaccat tatcttcagg
     4141 acttcctggc gagagccagg tacctgggcg actatcggat tggacgtcat cacgtcccct
     4201 acggtggttg gcatctagtt ctcctccccg gtggccctga ccacgaggac ggggcatttg
     4261 gcgaagcgaa ccacgcgctc ggcgacgcta cccaagagca atttggagaa accggtccga
     4321 cccagggtgc ccatgaccac caggtcgtgc tcggcggaga gatcgactat cttgcgggaa
     4381 ggagagcctt cctcgatgcg cgtcgttagc ttgacgccca aggcctcagc ctccttcttc
     4441 acatagtcca tggcctcctc gccctccttc tccagcagcg tataaacgct aacgatggtg
     4501 gagtccatgg ggaagttgat gaaggaggtc tggtccacga cgtaaagtgc ggtgacctcg
     4561 gcgccggtcg ccttggccat ctccaatccc ttggtaacgg cagccttggt gtattcgctc
     4621 ccgtcggtcg ggatcagtat cttcttgaac agagtcatcc tatcatctcc agcaattctt
     4681 acctatgcat accagctcag gcgcgtcaga ggcgctgcgc aacacgaggt cggagacggg
     4741 gtccccgccc cgctgcctga gcaccatcag ctcgcagcgt gctcccggtt ctatacttaa
     4801 cggttcctgg cgatttaata attttcttcc gttcatggcc atgtccagag cgtccttcgc
     4861 tccgttccgg ccctgcgaac gcaggaggcg ggcggccact tccatctcgg ccagcatgtc
     4921 cggtaggcat atcatggcgt tatcagttcc cagcgccacg atcaacccgc tatccaacat
     4981 ccttgctagc gggggcgtct tcccgaagaa caggttcgag cgggggcann nnnnnnnnnn
     5041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5101 nnnnnnnnnn nnnnnnnnnn nnnnnnnncc gtcagcgacc ttcagcagtc gtcgggcccc
     5161 ggagcggcag aactccaata gcttcggcct tcccatgatg atcgagtcgg ccccctcgcc
     5221 gtccaaacgc cgtaggtaat cggaaccatc ataaccgccc tctcggaaat ccagaaaatg
     5281 cgatacgccc cgacgggcca tgaagcgctt catggtcagc ataccgcgca tgatatcgtc
     5341 tggcgaggcc tgctccagga tccggtgctt cagacctttg ggcggagcga ccagctcctc
     5401 cagggatatc gcggggtcca cgggaacgat gtaatcggcg atgtgcgtat gaccgttgac
     5461 gaaggtgggg acgatcaatc cacgggcatg agcgttaccc ttctttccgc gtccgatctc
     5521 cgctatcact ccgtcctcga tgcccacgtg acccggaaaa aagccgttct ggcctagcac
     5581 cagcccggag agataacgca tatgcgctca aacgctctgt ccatatatca atcgcatggt
     5641 ggtaaagacc aaattgttgt tctgcgttcg ccgtcgggaa gtgcgcaagt gaacgacctc
     5701 ctggccctgg ccttcctgat gttcctggcg gtgagcgccc agctgatagc ctcgcgcttc
     5761 gggctgtcgg cggcgatatt cgagatattg ctggggctgg cggtcggaca agttctaggc
     5821 cttcgttctc tggagatcga gtggttctcg ttcctggccg ttctgggcgg aatcggcctg
     5881 accttcctgg ccgggacgga gatggaggtc gagcgcgtgc gaagtcaatg gaagagcagc
     5941 ttgcccctcg ccctggcctc cttcctctcc atattcatca ccgtgccgtt cgccctgcac
     6001 tatctcggcg gatggtcctg ggactcgtca cttttagccg ggatcgccct atcggaaaca
     6061 tccgtggcca tcgtctacgt cgttttggtg gagggcggta gggcgcggac ggacaccggt
     6121 tccgtgatat tggcggcctg cttcctgacg aacctgatcg cctccatcgc tctggcggta
     6181 ctgttcgccc ctcccggatc ggaggttctc ttactaattc tggccgggct tctgctcgtg
     6241 ccgttggcct atcgctacac cggcaaggtc ctggaccgct tcaagggccg tccgggagag
     6301 ccggagatca agctagtgct gcttccattg ctgttattgg ccggcctggc ctccatggcc
     6361 ggcgtggccg cggtacttcc cgcctatctg ctcggcttcg ccatgtcccg ctccctgaac
     6421 gaacggaggg aggcgtggtc caaggtccgc accgtcttcc tgggcttcat ggtctccctg
     6481 ttcttcctgg ccgccggttc caacgtctcc atggaggcgc tgctggtcgg cgccgcgatc
     6541 atcatcgccc tgggcttcgg cagggtggtc ctcaagatgc tgttcgtgct gccgacggtt
     6601 agcgtttcgc tacgccagga ccgggtgtac atcgccctgc tgatgtccac gtcgttaact
     6661 ttcggaatgg t
//
LOCUS       DAOPZI010000049         5962 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_16533_length_5962_cov_9.185543, whole genome shotgun sequence.
ACCESSION   DAOPZI010000049 DAOPZI010000000
VERSION     DAOPZI010000049.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 5962)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5962)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5962
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_16533_length_5962_cov_9.185543"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..686
                     /locus_tag="PKM11_07655"
     CDS             <1..686
                     /locus_tag="PKM11_07655"
                     /inference="COORDINATES: protein motif:HMM:NF013143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HNX48415.1"
                     /translation="VDGVAHTAFGGVAVGLLIGIDPMLGAMAVSAAAVLGITYMRRKG
                     LAQSDAAVAVMMAMGFSLGMIVISMANGFNVELFSYLFGSILTIDNTDLTVLIVLAVV
                     IIGFMVFFYKEMLAITFDEDGARLQGIPVQAMTMAFNLLVAVTIALSIKVIGIILVVA
                     LMVLPGLTALQLKRSFKTTLIASTIFGVAAAILGIVLSVLFSVSTSGVIVFSAAGIFL
                     FVAAYQRLA"
     gene            918..2021
                     /locus_tag="PKM11_07660"
     CDS             918..2021
                     /locus_tag="PKM11_07660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase family protein"
                     /protein_id="HNX48416.1"
                     /translation="MDSRWHGNAAKRFASPFVDNPHDRIDVDPIILSNAAVACGYTIR
                     DFYEKPELGIHCVGYISHLFDLLPVTHWFFSLPWVTELGLKLHYKETLPPISTGPIYS
                     EPEDVDKMRVIPKEELVKATGEFATVPKFFRIYDYVAKNLPMTLVPISYGFDLVGAAA
                     EMVGVENFIMWTFTEQDQADKLVKIYTDTAVNGAEALADKYGMAMLIVGSVLGNNDIF
                     SDEGVERYSVKNMFRYVDGCFKHGAGPQIFYHLCGNHQTDYKLFKDGLMWSPFTVIHA
                     GYQGRNPFPSGLLKETFQDKATCMGSVDTKLMIDNNPNKVYNQAKEQLLQGRDSKKGY
                     ILGTSCETPPYTIPGQMLALVKAARDFGTYGTW"
     gene            2027..2476
                     /locus_tag="PKM11_07665"
     CDS             2027..2476
                     /locus_tag="PKM11_07665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48417.1"
                     /translation="MVTVTIPAEVKELIAKRGLKESDVMDVVNTAAQTGKYIKKGNDG
                     LAKKVIGGLTVYVLSDLSGHGTAVVKTAYAHKMAMGKIVNVMAETEWKTHDGKPVAQG
                     HVEMEYMTVKRTGPALVDPATGDGWVEEYLAVKTLAAAEGLFEKKRA"
     assembly_gap    2740..2839
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <2840..4137
                     /locus_tag="PKM11_07670"
     CDS             <2840..4137
                     /locus_tag="PKM11_07670"
                     /inference="COORDINATES: protein motif:HMM:NF015983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HNX48418.1"
                     /translation="DDKVYLIKECPEHGTEKVLIWRGREDYIDMNRYAAVQSKPLKIA
                     VEKSDDCPQICGLCPDHVQHTCLVVMEITNGCNLKCPVCFASANQFYKFSPSLEVIRG
                     MYQTMLDYVSHPIVVQISGGEPTIRDDLPDIIRMGKEMGIDYIEINTNGIRFAEDIEF
                     LKKVKEAGADDLYFSFDGLHGDIYKQTCGRDILDQKMKCIENCEKVGMGITLVTVVSP
                     NINLDRVGEVINFAKSKVPTIKGVHFQPISYFGRFPISPKDGDRVTIPDLLKAIEEQT
                     NGELRMDNFIPTSCSNVHCDAKSMSVVMEDGSLFPLTSRAFGPPKDTANVANKTRKEI
                     SDLWRFIEDSLIVEEDDGTKSEWGDFVDRAKTHYLTVSTMAFQDAWTSETERFRNCCI
                     HTVTPDGKLIPFCLFNINSMEGKTLYRHEMWSKYSENSK"
     gene            complement(4173..4478)
                     /locus_tag="PKM11_07675"
     CDS             complement(4173..4478)
                     /locus_tag="PKM11_07675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48419.1"
                     /translation="MPLTPELRRAGVTPELMNTTRRFACPNCGKEFSLMQSRAIACRG
                     CRQASTNCRYARCPYCDKEFPMEQVITKNKYGEKHLAAYANNILGNYYTQFGKRNSR"
     gene            complement(4555..5331)
                     /locus_tag="PKM11_07680"
     CDS             complement(4555..5331)
                     /locus_tag="PKM11_07680"
                     /inference="COORDINATES: protein motif:HMM:NF014635.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF169 domain-containing protein"
                     /protein_id="HNX48420.1"
                     /translation="MADALLETWARDFRSELNLGTYPIGVKLFEKASEALAIPGVKVL
                     RSTATCHMAALARHYRDDGISVTTAQGMKCLWGLACLGLIKTPERLARGDLNLAFTKN
                     GEAAHNLQDNIFMLGNDGQRYNAMLMAPLDLMPVRPDAIVAYMTPGQSLKVLLGYEYQ
                     DGRVLKGTTLTGQSTICSAIARVMNGEDLVLDIPCVGDRTWGLVPDQELVVAISPKIF
                     GEVLEGMKATDRFAAHPFRPFLNWSVIFPPEMEPRPKELD"
     gene            5409..>5962
                     /locus_tag="PKM11_07685"
     CDS             5409..>5962
                     /locus_tag="PKM11_07685"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48421.1"
                     /translation="MSLKKRIIMAYARTKLTSRKVSEDVENPLHDWVQLKVRNAFKRD
                     EAFRKALGRDVLEEIDRKTFEEYQLYKFRKQMAYVMENSPFYQKRYGEAGIRPEDIRT
                     MADLDKVPLTDPDDLAEEPFLFLCVSQSKISRTFSTSGTSGKPKRLFYTSDDLLNIVD
                     SIAAALRSTGLKSSETLHIMFPAVV"
BASE COUNT         1345 a         1631 c         1632 g         1254 t
ORIGIN      
        1 tggtggacgg ggtggcgcac accgcgttcg ggggcgtggc cgtaggattg ttgatcggaa
       61 tagatccgat gctaggggcc atggccgtat cggccgcggc ggtgctcggc atcacttaca
      121 tgaggaggaa aggattggcc caatcggacg ccgccgtggc cgtcatgatg gccatgggtt
      181 tctccctcgg gatgatcgtc atctccatgg ccaacggctt caacgtggaa ctcttcagtt
      241 acctgttcgg ttccatactg accatcgaca acaccgatct tacggtgctc atcgttctgg
      301 cggtggtcat aatcggtttc atggtcttct tctacaagga gatgctggcc atcaccttcg
      361 atgaggacgg cgcgcggctg caggggatac cggtgcaggc catgaccatg gccttcaacc
      421 ttctggtggc ggtgaccata gccttgtcga tcaaggtcat cggcataatc ctggtggtcg
      481 ccctgatggt gttgcccggg ctcaccgctc tgcagctgaa gaggtccttc aagaccactc
      541 ttatcgcttc tacgatcttc ggggtggcgg ccgcgatact gggaatagtt ctctccgtgc
      601 tgttcagcgt ttcgaccagc ggagtgatcg ttttcagcgc tgccggaata ttcctgttcg
      661 tggcagccta ccaacgactg gcctgagact ggcgctctgc gggcgttacg tttcttaata
      721 acgaaatgat aaaaagatgc actatttttg taattaattt taataattta cctaaatttg
      781 aaattaattt ctatttagca cttaaatata gggtgttaat gaaacttttt ttcacaagcc
      841 atcaacaacc attatatagg gtccatgagg ttagtggctc ggggatttca atgggctacg
      901 aagaaatgtt tccagccatg gatagcaggt ggcacggtaa tgccgccaag cgctttgcga
      961 gcccctttgt agacaaccca catgaccgca tcgacgtgga cccgatcatc ttgtccaacg
     1021 ccgctgtggc ctgcgggtat actataaggg acttctatga aaaaccggag ttgggtatcc
     1081 actgcgtcgg ctacatatcc catctctttg acctactacc agttacgcac tggttcttct
     1141 cattgccgtg ggtcactgag cttggactta agctgcacta caaggagacc ctgccgccga
     1201 tctctaccgg tccgatatac tcggaacccg aagatgtcga caagatgagg gtaatcccga
     1261 aggaggagct ggtaaaggct accggcgaat tcgccactgt acccaagttc ttcaggatct
     1321 acgactatgt cgctaagaac ctgcctatga ccttggtgcc gatctcatac ggtttcgacc
     1381 ttgtgggcgc ggctgctgag atggtcggcg tcgagaactt catcatgtgg acgttcaccg
     1441 agcaggatca ggcagacaag ctggtgaaga tctacaccga cactgccgtc aacggcgctg
     1501 aggcattggc tgacaagtat ggaatggcga tgttgatcgt cgggtccgtc ttgggcaaca
     1561 acgatatctt cagcgacgag ggcgtcgaga ggtactctgt gaagaacatg ttcaggtacg
     1621 tggacggatg cttcaagcat ggagctggac cgcagatatt ctatcacctg tgcggtaacc
     1681 accagaccga ctacaagctg ttcaaggacg gcttgatgtg gtccccgttc accgtgatac
     1741 acgctggtta ccagggcagg aacccgttcc cgtccggcct gctgaaggag accttccagg
     1801 acaaggcgac ctgcatggga tccgtcgaca ccaaactgat gatcgacaac aacccgaaca
     1861 aggtgtacaa ccaggccaag gagcagctgc tccagggacg cgactccaag aagggctaca
     1921 tcctaggtac ttcttgcgag actcctccgt acactatacc cggacaaatg ttggccttgg
     1981 tcaaggcggc tagggacttc ggtacctatg ggacatggtg attcaaatgg taactgtaac
     2041 tataccagcc gaagttaagg agctcatcgc gaagaggggc ctgaaggaat ccgacgtcat
     2101 ggacgtcgtg aacaccgctg cccagactgg caagtacatc aagaagggaa acgatggact
     2161 ggccaagaag gtcatcggcg ggctaaccgt ctacgttctc agcgacctgt ccggtcacgg
     2221 caccgccgtt gtcaagaccg cctacgccca caagatggcg atgggcaaga tcgtcaacgt
     2281 catggccgag accgagtgga agacccacga tggtaagccg gtcgctcagg gacacgtcga
     2341 gatggagtac atgaccgtca agaggactgg tccggctctg gtcgaccccg caactgggga
     2401 cggctgggtc gaagagtact tggccgtcaa gaccttggcc gctgccgagg gtctcttcga
     2461 gaagaagcgc gcttaaaaca acttcaggcc gctaaacgcg gcctttcctt tttacttttt
     2521 tattatcgcg cggaagcgcc tttccgtttt tcaacaaaaa gtagaatagt ggcacatgac
     2581 attccagttg gatattgcgg tgaaagaaat gagcgaggtc atcggtcaaa ccaaggggct
     2641 ctgccccaag tgcttgaaga ccatcccggt caccaaggtc gtagaggacg ataaggtcta
     2701 tctcatcaag gagtgccccg agcacggaac ggagaaggtn nnnnnnnnnn nnnnnnnnnn
     2761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2821 nnnnnnnnnn nnnnnnnnna ggacgataag gtctatctca tcaaggagtg ccccgagcac
     2881 ggaacggaga aggtgctgat ctggagaggt agggaggact acatcgacat gaaccgctac
     2941 gccgccgtgc agtccaagcc tctgaagatc gccgtggaga agagcgacga ttgcccgcag
     3001 atttgcgggc tgtgccccga tcacgttcag cacacctgcc tggtggtcat ggagatcacc
     3061 aacggttgca acctcaagtg cccggtgtgc ttcgcctccg ccaaccagtt ctacaagttc
     3121 agtccctccc tggaggtcat ccgcggcatg taccagacca tgctggacta cgtcagtcat
     3181 cctatcgtcg tccagataag cggcggggaa ccgacgataa gggacgatct acctgacatc
     3241 atccgcatgg gaaaggagat gggcatagat tacatcgaga tcaacaccaa cggcatccgt
     3301 ttcgcggagg acatcgagtt cctcaagaag gtcaaggagg ccggggcgga tgatctttac
     3361 ttctccttcg atgggttgca tggggacatc tataaacaga cctgcggccg cgacatcctg
     3421 gaccagaaga tgaagtgcat cgagaactgc gagaaggtgg gcatgggcat aactctagtg
     3481 acggtcgttt ccccgaacat caacctggac cgggtcggcg aggtcatcaa cttcgccaag
     3541 tccaaggtgc cgaccataaa gggcgtacac ttccaaccaa tatcctactt cggccgtttc
     3601 cccatctccc cgaaggacgg cgaccgggtg accatccctg atctgctcaa ggctatcgag
     3661 gagcagacca acggcgagct ccgcatggat aacttcatac ccacgtcctg ctcgaacgtc
     3721 cattgcgacg ccaaatcgat gtccgtggtc atggaggacg gttctctctt ccccctgacc
     3781 agcagggcat tcggaccgcc caaggacacc gcgaacgtcg ccaacaagac ccgcaaggag
     3841 atatccgacc tttggcggtt catcgaggat tcgctcatag tcgaagagga tgacggtacg
     3901 aagagcgagt ggggcgactt cgtcgatagg gccaagaccc attatctcac cgtatcgacc
     3961 atggccttcc aggatgcctg gacgtcagag acggaacgct tccgcaactg ctgcatccac
     4021 accgtgaccc cggacggaaa gctgatcccc ttctgcctgt tcaacatcaa ctccatggaa
     4081 gggaagacgc tctatcgaca tgagatgtgg tcgaaataca gcgagaacag taagtaaagg
     4141 ggcttaggcc cccttttatt attttaaaaa ctttaacggg agtttctctt cccgaactgg
     4201 gtgtaatagt tgcccaggat gttgttggcg taggcagcca gatgcttctc gccgtacttg
     4261 ttcttggtga tgacctgttc catcgggaac tccttatcgc agtaagggca gcgggcatag
     4321 cggcagttag tgctggcctg gcggcaaccg cggcaggcga tggcccggga ctgcatcagg
     4381 ctgaactcct taccacagtt gggacacgcg aaacgcctgg tggtgttcat cagttccggc
     4441 gtcactcccg ccctgcgtaa ttctggtgtc agcggcatat catcactctg gcgtcttaac
     4501 cacgttcata atatattgat tttcccccgt ttacgtttct ataaggaact ttcgtcagtc
     4561 cagctccttc gggcggggct ccatttccgg tggaaatatc actgaccaat tgaggaacgg
     4621 ccggaacgga tgcgcggcga acctgtccgt ggccttcatg ccctccagta cctcaccgaa
     4681 gatcttaggg gatatggcga caactagttc ctgatcagga acgaggcccc aggtgcggtc
     4741 tccaacacaa ggaatgtcca gcaccaggtc ctcaccgttc ataacccggg cgatcgccga
     4801 gcagatggtg gattggccag tcagcgtagt gccttttagc accctaccat cctggtactc
     4861 gtaaccaagc agtaccttca gcgattgtcc cggggtcatg taggccacga tggcgtccgg
     4921 tcgcaccggc atgaggtcca ggggcgccat cagcatggcg ttgtaccttt gcccgtcgtt
     4981 gccaagcata aagatgttgt cctgcaggtt atgcgcggcc tccccgttct tagtaaaagc
     5041 aaggttcaga tctcctcggg ccaagcgctc cggcgtcttg atcaagccca agcaagccaa
     5101 tccccagagg cacttcattc cctgggccgt ggtcaccgat attccgtcat cccgataatg
     5161 acgagcgagc gctgccatgt ggcaggtggc cgtggagcgc agcaccttga cgccaggtat
     5221 cgccagagcc tcggaggcct tctcaaaaag tttgacaccg ataggatagg tccccaggtt
     5281 caattcggac cggaaatccc tggcccacgt ctccaacaac gcgtccgcca tgtccgggaa
     5341 atgagcttct tgtcttaata gccctgcggt ttgaaaataa tatatgggca tgagggcatt
     5401 cgccaccgat gagcctcaag aagcgcatta tcatggccta cgcccgcacc aagctcacct
     5461 ctcgcaaggt atcggaggac gtggagaacc cgctgcacga ttgggtgcag ctcaaggtgc
     5521 gcaacgcctt caagcgcgac gaggccttcc gcaaggctct gggccgggat gttctagagg
     5581 agatcgatcg taagacgttc gaggagtatc agctctacaa gttccgcaag cagatggcct
     5641 atgtgatgga gaacagcccc ttctaccaga agaggtacgg tgaggctggc atcaggccgg
     5701 aggacatccg gaccatggcc gacctggaca aagtgccgct caccgacccg gacgacctgg
     5761 ccgaggagcc gttcctgttc ctctgcgttt cacagagcaa gatatcccgc accttctcca
     5821 cgtccggaac atcgggcaaa ccgaagaggc tgttctacac cagcgacgac cttctgaaca
     5881 tcgtcgactc catcgccgcc gcgttgcgct ccaccgggct gaagagcagc gaaacgctgc
     5941 acatcatgtt cccggccgtc gt
//
LOCUS       DAOPZI010000050         5288 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_19679_length_5288_cov_6.724250, whole genome shotgun sequence.
ACCESSION   DAOPZI010000050 DAOPZI010000000
VERSION     DAOPZI010000050.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 5288)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5288)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5288
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_19679_length_5288_cov_6.724250"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(4..525)
                     /locus_tag="PKM11_07690"
     CDS             complement(4..525)
                     /locus_tag="PKM11_07690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX48422.1"
                     /translation="MSMVEELVSGILRSEEGFREALRKILEEELKISVPEFCEKTGLS
                     PSTIYKILQEQREPNLRTVRAAIKGVRKMDANPGGEFIAVIASRPVLNKIEERMMKVG
                     DRNVRVKEYPASTMEDAIIAAVKAERDGALALVCAPIVAPTVEQIVRIPVSVVVPKDS
                     MVRAIEIAASKVL"
     gene            complement(530..1417)
                     /locus_tag="PKM11_07695"
     CDS             complement(530..1417)
                     /locus_tag="PKM11_07695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HNX48423.1"
                     /translation="MDFDVAVIGAGPAGLQAALHAARKKVKVCVLGKVQNSALLKAEI
                     ENYFGTEPRAGKEMLEITAKAAAGFGAVLLEEDLLNIEMEGGAFKLKTESLKEIMAKA
                     VILAPGISRKKLNVEGEKEYHGLGVSYCATCDCNFFKKKTVAILGDASMAASAALLLR
                     EYASKVYWVAKEFKASPELMQKVKATDIEKVQAWPTKIHGDQVVRGMMLDDGRDLTLD
                     GVFIELGAKGVADLAMEVNIFPDENGYIAVDRHCATDTPGVFACGDVTGLPWQLAKAV
                     GEGCVAGLSAASYVRKEKE"
     gene            complement(1484..1888)
                     /gene="trxA"
                     /locus_tag="PKM11_07700"
     CDS             complement(1484..1888)
                     /gene="trxA"
                     /locus_tag="PKM11_07700"
                     /inference="COORDINATES: protein motif:HMM:NF012314.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HNX48424.1"
                     /translation="MAEDELTEIRRRKLEALMGQSEQKGVKKLSGVTEVKDSTFEEFI
                     NSAPLVIVDCWAPWCGPCRMLAPIVEQLSEEFEGKIKFGKMNTDENENTPMKFNITAI
                     PTMLVFKNGAQLDRIVGAGNKDFMRQKFSKYL"
     gene            2108..2380
                     /locus_tag="PKM11_07705"
     CDS             2108..2380
                     /locus_tag="PKM11_07705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="HNX48425.1"
                     /translation="MLEEASELIGMQVYTPNGVFLGNVNNLVIDVDTRKVDGLFINES
                     NPLLVEDSKAVNVPFRWIQAIGDVVLLKYFPKRVTARRPAAKPAQP"
     gene            2420..2917
                     /locus_tag="PKM11_07710"
     CDS             2420..2917
                     /locus_tag="PKM11_07710"
                     /inference="COORDINATES: protein motif:HMM:NF012360.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HNX48426.1"
                     /translation="MPERKVFVDPAAVIIGDVELDDAVSIWPTAVLRGDANSIRIGAG
                     TNVQEGAVVHTSHDFPTVIGKFVTIGHGAVINGAKIGDRCIIGINSTILDGAIIGDEC
                     IVGASALVTGMMEIPPRSVVMGLPGKVVRHNDLTIKERAERSAQSYIELKDLHLEGRF
                     PRRTY"
     gene            2961..3545
                     /locus_tag="PKM11_07715"
     CDS             2961..3545
                     /locus_tag="PKM11_07715"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48427.1"
                     /translation="MWRTGFRGWFYLSIAAALVVSLRNFDAYWLILEMGMVAAILGRY
                     PLFDQPEEPELQRPLTLFMVFPFTVYVALNLFDLGEGVLLRSISTLITMMASLLLCLF
                     LILNLVKRTGFHMNYRFILGFATMTSISLASFFILLETSYSVLVGIEASNDELMWSLI
                     GTLTGGVISGLLFKRDMRRMDYTGLLVVSPEEDR"
     gene            3542..4168
                     /locus_tag="PKM11_07720"
     CDS             3542..4168
                     /locus_tag="PKM11_07720"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48428.1"
                     /translation="MKVMKGTSVVFLASEIAIVLMGALAYSEGRSYPGNGAVMGALIM
                     TLPFLLEKAGLFRMPLSMQIWASLAVGLHTFGLLVGLYDSTWWWDDLTHLVSSAMVGT
                     IAALALYLFDLHSVKIKVPRWAYPMMIVVFSIFIGTIWEIAEFAGDVLASTRMQYSLS
                     DTLGDCYMDMLGGLMASMMWALWFWKDRDGKLADSTQKPLIDLFERVF"
     gene            4271..>5288
                     /locus_tag="PKM11_07725"
     CDS             4271..>5288
                     /locus_tag="PKM11_07725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HNX48429.1"
                     /translation="MDVWNPHIEKLPKAQLDALQLKLLKIQTRRMWEFSPFYRERMRT
                     AGVAPDDIRTLKDVRKLPFMTKKDLRDGYPNKLMMRDRGDLLRYHASSGTTGKATIVG
                     YTKNDLENWSESLARAMTSFGLGKNDVIQVANTYGLFSGGLGFHYATEKMGATVIPAS
                     TGNTDRQLELICDLGVTAMAATPSYLMYLGEVAEKKGIDIHKDTKLRYGLLGGEPWSD
                     RMRDRIYEKMGVRGFNCFGASELSGPLFMECAEQDGIHFWGDLAYLEIVDPETGEPLE
                     PGQKGEMVVTMLQKEAFPMMRYRMGDITSIMEEPCPCGRAHPRITRIQGRVDDMIIIR
                     GINVF"
BASE COUNT         1058 a         1545 c         1530 g         1155 t
ORIGIN      
        1 tgatcacagc accttggagg cggctatctc tatagcccgc accatgctgt ccttcgggac
       61 caccacggac accggtattc tgactatttg ctccacggtc ggggccacga tcggagcgca
      121 gaccaacgcc aacgctccgt ccctctccgc cttcacggcg gcgattatgg cgtcctccat
      181 ggtgctggcg ggatattcct tcacccgcac gttcctgtcg ccgaccttca tcatcctctc
      241 ctcgatcttg ttgaggaccg gacgggaggc gatgacggcg atgaactccc cgccaggatt
      301 ggcgtccatc ttccggacgc ccttgatggc cgcgcgaacg gtgcgcaggt taggctctcg
      361 ctgctcctgc agtatcttat agatcgtact gggagagagg ccggtcttct cacagaactc
      421 agggacggat atcttcagct cctcctcgag tatcttccga agcgcctcgc gaaagccttc
      481 ctcgcttcgg agaattccgg agaccagctc ctccaccatg ctcatgatat cactcctttt
      541 ccttccggac gtagctggcg gcggaaagtc cggccacgca tccttccccg accgccttgg
      601 ccagctgcca tggcagaccg gtaacatcgc cgcaggcgaa gacgccaggg gtgtccgtgg
      661 cgcaatggcg gtcaaccgcg atgtatccgt tctcgtccgg gaagatgttg acctccatgg
      721 ccagatcggc cacgcccttc gcgcccagct cgatgaacac accgtcgagc gtcaggtcgc
      781 gaccgtcgtc cagcatcatt ccgcgcacca cctggtcacc gtgtatcttg gtcggccagg
      841 cctgcacctt ctcgatgtcg gttgccttca ccttttgcat cagttccggg gaggccttga
      901 actccttggc cacccagtag acctttgatg cgtactcacg aagcagcaga gcggcggagg
      961 cggccatgct ggcatcgccg agtatggcca ccgtcttctt cttgaagaag ttgcagtcgc
     1021 aggtggcgca gtacgacacc cccagaccgt ggtattcctt ctccccttcc acgttcagct
     1081 tcttgcggga tatcccggga gcgaggatca cggccttggc catgatctcc tttagagatt
     1141 cggtcttcag cttgaaagcg cctccttcca tctcgatgtt caggaggtcc tcttccaata
     1201 ggaccgctcc gaaacctgct gccgccttgg cggttatctc gagcatctcc ttgccggccc
     1261 gaggttccgt accgaaatag ttctcgatct ccgctttcag caaggcgctg ttctgaacct
     1321 ttccaagaac gcataccttg accttcttgc gcgcggcgtg cagggcggcc tgaagaccgg
     1381 ccggccccgc tccgattaca gcaacgtcga aatccatcga aatcccagct ttaacaaaat
     1441 tatatgatta aacggtttgg agaaaaaggt ttgcagtgcc ccctcagagg tacttggaga
     1501 acttctgcct catgaagtcc ttgtttccag cgccgacgat gcggtccagc tgggcgccgt
     1561 tcttgaacac cagcatggta gggatggcgg tgatgttgaa cttcattgga gtgttctcgt
     1621 tctcgtcggt gttcatcttg ccgaacttta tcttgccctc gaactcctcg gagagctgct
     1681 ctacgatagg cgcaagcatg cggcagggac cgcaccacgg ggcccagcag tctacgatca
     1741 ccaacggtgc gctattaatg aactcctcga aagtgctatc cttgacctcg gttactccag
     1801 acaatttctt cactcctttt tgttcgctct gacccatcaa tgcctctaac ttgcgtcttc
     1861 tgatctcggt aagctcgtcc tcggccatca gaagaccccg ctcaatcggt tgtgcattgt
     1921 gattacaaaa ccgtattgaa gttccaccgt atataatctt tatcacaatc cttcctggaa
     1981 ggcgaaattt ccccttaggc ggtaataatg ggaagccgcg ggaccgacgc acaaatgcgc
     2041 gaagccagga tttcacgctg ataatctttt taatagggga tggcgatatc tgacaaaggg
     2101 agtgccgatg ttagaggagg cttctgagct catagggatg caggtctaca cgcccaacgg
     2161 agtgttcctg ggaaacgtga acaacttggt catcgatgtg gatacccgca aggtcgatgg
     2221 gctcttcata aacgagtcca accccctgct ggtggaggac tccaaagcgg tcaacgttcc
     2281 cttccgctgg atccaggcca tcggggatgt cgtactcctg aagtacttcc ccaagagggt
     2341 caccgcccgg cgccccgccg ctaagccggc gcagccttga ggccaaccta ttttttctat
     2401 aattttcata tcgttcaata tgcctgagcg caaggtcttc gttgacccgg cggccgtgat
     2461 catcggcgat gttgagctgg atgacgcggt ctcgatctgg ccgacggccg ttctgcgagg
     2521 tgacgccaac tccataagga tcggggcagg gaccaacgtc caggaaggtg cggtcgtgca
     2581 caccagccat gattttccaa ccgtcatagg taaattcgtc accatcgggc acggggcggt
     2641 cataaacggc gccaagatcg gcgatagatg catcataggc atcaactcca ccatacttga
     2701 cggggcgatc atcggcgacg agtgcatagt cggggcgagc gccctggtca ccggaatgat
     2761 ggagataccg cctcgatcgg tggtgatggg tcttccggga aaggtcgtgc ggcataacga
     2821 ccttaccatc aaggagaggg cggagaggag cgctcagagc tacatcgagc tcaaggacct
     2881 gcatctggag ggcaggttcc cccgaaggac ctattgacca ggtcgggcga tcgatactga
     2941 cacggagatg ctgagataac atgtggagga caggtttccg gggttggttc tatctgagca
     3001 tcgccgcggc cctggtggtc agcttgagga acttcgatgc atactggctc atcctggaga
     3061 tgggcatggt ggcggccatt ctgggccgct accccctttt cgatcagccg gaggagccgg
     3121 agctgcaacg tcccttgacc ttgttcatgg ttttcccgtt cacggtatac gtggccttga
     3181 acctgttcga tctcggggaa ggtgtgctcc tgagatcgat cagcaccctg atcaccatga
     3241 tggcctcgct gctgctatgc ctgttcctga tcctcaacct ggtcaagagg acggggttcc
     3301 acatgaacta ccgattcata ctggggttcg ccaccatgac atccatttca ttggcctcct
     3361 tcttcatcct cctggagacg tcgtattccg tcttggtcgg tatcgaagcg tccaatgacg
     3421 agctcatgtg gtccctcatc gggaccctga ccggaggggt gatctccggg ctactgttca
     3481 agagggacat gcggaggatg gactacaccg gcctcctggt ggtatcgccg gaggaggaca
     3541 gatgaaggtc atgaaaggaa catcggtggt gttcctggcc tccgagatcg cgatcgtgct
     3601 catgggcgcc ctggcctatt ccgaaggccg gagctaccct ggcaacgggg cggtgatggg
     3661 ggcgctaata atgaccctcc cgttcctgct ggagaaggcg gggttgttca ggatgcccct
     3721 gtccatgcag atctgggcgt cgctcgcggt gggcttgcac acgttcggtc tgctggtcgg
     3781 actgtacgac agcacctggt ggtgggacga tctcacccac ttggtgtcct ccgccatggt
     3841 gggaacgatc gccgcgctgg ccctctacct gttcgacctg cactccgtca agatcaaggt
     3901 gccccgctgg gcctatccga tgatgatcgt ggtcttctcc atcttcatcg gtacgatctg
     3961 ggagatcgcc gagttcgccg gggatgtgct ggccagcaca cgaatgcaat attcgttgag
     4021 cgatacgctg ggggactgct acatggacat gcttggcggc ctgatggcca gcatgatgtg
     4081 ggcactatgg ttctggaagg accgggatgg aaagctggcc gattcgacac agaagccctt
     4141 gatagatctc ttcgaacggg tcttctgagg gtgaagcaga ccttggagag cataaatatg
     4201 atgcgtgtta tcaccgtaca cgcctgaccg cgcggggcgc cgccctgccc gtgtcctcgg
     4261 aggaaggtgc ttggacgttt ggaaccccca tatcgagaaa ttgcccaagg cccagctgga
     4321 cgcgctccag ctgaagctgt tgaagataca gacccgccgc atgtgggagt tctctccgtt
     4381 ctaccgcgag cggatgagga cggcgggggt cgcaccggac gacattagga cgcttaagga
     4441 cgttcgcaag cttcccttca tgaccaagaa ggacctccgt gacggctacc cgaacaagct
     4501 gatgatgcgc gatcgcggag acctgttgcg ctatcacgcc tcctcgggaa ctacggggaa
     4561 agcgaccatc gtcggttaca ccaagaacga cctggagaac tggtcggaat ctctggccag
     4621 ggcgatgaca tcgttcgggt tgggaaagaa cgacgttatc caggtggcca acacctacgg
     4681 tcttttctcc ggaggtctgg ggttccacta cgccactgag aagatgggag cgacggtcat
     4741 cccggcgtcg accgggaaca ccgacagaca gctcgagctt atctgcgatc tcggcgtcac
     4801 ggccatggcc gccacgcctt cctacctgat gtaccttgga gaggtggccg aaaagaaggg
     4861 catcgacatc cataaggaca ccaagctgcg ttacggactt ttaggcggag aaccgtggag
     4921 cgaccgcatg cgcgaccgca tctacgagaa gatgggcgta cgcggcttca actgctttgg
     4981 tgccagcgaa ctctccggac cgctgttcat ggaatgcgcc gagcaggacg ggatccactt
     5041 ctggggggac ctggcatatc tggagatagt cgaccccgaa acgggcgagc cgctggaacc
     5101 aggtcagaaa ggagagatgg tggtcaccat gctgcagaag gaggcgttcc cgatgatgcg
     5161 ctaccgcatg ggcgacatca cctcgataat ggaggagccc tgcccttgtg gccgggcgca
     5221 cccgcgcatc acgcgcatcc aggggcgcgt ggacgatatg attattattc gcggcatcaa
     5281 tgtgttcc
//
LOCUS       DAOPZI010000051         5165 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_20325_length_5165_cov_9.352642, whole genome shotgun sequence.
ACCESSION   DAOPZI010000051 DAOPZI010000000
VERSION     DAOPZI010000051.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 5165)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 5165)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5165
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_20325_length_5165_cov_9.352642"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..314)
                     /locus_tag="PKM11_07730"
     CDS             complement(<1..314)
                     /locus_tag="PKM11_07730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lyase family protein"
                     /protein_id="HNX48430.1"
                     /translation="MLICPLDFRYGRKEMKTIFSEDHRIDLQLKVEAALARAHAKAGN
                     IPRSAAREITCAASIDIVTRERVYEIEAETKHDVMAVVKALSEKCGTAGNYVHLGATS
                     ND"
     gene            453..1958
                     /gene="gvpD"
                     /locus_tag="PKM11_07735"
     CDS             453..1958
                     /gene="gvpD"
                     /locus_tag="PKM11_07735"
                     /inference="COORDINATES: protein motif:HMM:NF018756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gas vesicle protein GvpD"
                     /protein_id="HNX48431.1"
                     /translation="MSATNAGALPREIIDFLLSPGGHSLLIKGDAGTGKTTMALQTIE
                     ALSDRQPEYYLSSRVSDVALYHQFPWLKERVEKNQLMKAGMAFLRRSWNSDGSKRNAL
                     EDAELRVERRELNRLEGQIEAGELGLEDEEGPSLNADGSLTVEVGSILPELEMAYDIA
                     ESNLPKKTLVVLDSVEALAENYGIPAYRIMNALQKDLVEKAGTNVVFVMETAERSHLD
                     YLGDGIVVLRNTVHGNNRVRTIEIEKLRGSSIQNWKYLFTLQGGRVTVVERDLDLRGV
                     QLSRNQMELPAGRGSFGWSELDRLFGGAPLGSLTLVEMGAGIPMDLLERIEVSLVEEH
                     LRQGRGVLWYPQRTLDHSSTQGIMPGTSLETLHVLDPSEASGSWPFVKKLEGTDLAND
                     LRWDSLKYLLKGSQEPYLSVLGLDALESVYGKVVPKLMQHVDLMRRGGHMVVLEATDG
                     SAGLETLSHQARLHLRLENLNGSVLLRGIKPTTISYCLDMTDGVPLWKPML"
     gene            2020..2352
                     /locus_tag="PKM11_07740"
     CDS             2020..2352
                     /locus_tag="PKM11_07740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48432.1"
                     /translation="MAKSALKLSRLLADEYSGRILSLTFSQPRSVQEICALSGIPIAV
                     AYRRIIALEASGLIKCLRTEVSPTGKRCKYYICQVDVARLTFKEGRFEVEVEWRDHMR
                     ADAIRVLE"
     gene            2398..2766
                     /locus_tag="PKM11_07745"
     CDS             2398..2766
                     /locus_tag="PKM11_07745"
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HNX48433.1"
                     /translation="MGKEDLLGKSRLLTDEYAVKILTATVRTPRSAQQISAQFGIPIA
                     ACYRRIRDLEVAGLIRCTERRLSRQGKRVCFYQSRIRTAALQYENGRLKVRFTMLDET
                     QNSDWQDVDLHEDRNDGDGR"
     gene            2882..3754
                     /locus_tag="PKM11_07750"
     CDS             2882..3754
                     /locus_tag="PKM11_07750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HNX48434.1"
                     /translation="MTELLEDLDQKRQFNNNEAEKHRRLRDELNDKTKEWVQKRDELN
                     SKVRELVDSAAKHRENRDKMNEQVRAAKDARDKFNEQVSELNKKVMALKKDNVPQEGP
                     SVAKLKKDLKQLEFIHMTSGDLKRDKEKALVEQMKALQIQIREREKSLEANDEVREAI
                     TLLREAKDKAEEQHRLVSELAEGAQNAHDSMIKIYEEADKLRKEADEAQEKFIETKGK
                     ADEEHRRHIDNIRQVHDYDKIITGLRQKARKARKKKDESVAMKESEEIFDKFKRGEKL
                     STEDLMVLQKSGYL"
     gene            4003..>5165
                     /locus_tag="PKM11_07755"
     CDS             4003..>5165
                     /locus_tag="PKM11_07755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle receptor subunit
                     alpha"
                     /protein_id="HNX48435.1"
                     /translation="MVLEGLGQSLRDVLKKVANSSNVDDKLIKEVSKDIQRALLQADV
                     NVKMVLEITKEVERRALTEKPPAGKSGREHVIKIIFDELVKILGEQRTLPLGKQVIMM
                     VGLYGQGKTTTAGKLGRYFHKKGLKVGLIAADVHRPAAYDQLKQIGDKIGVQVYGSPA
                     ERSAVNIVETGMKQFSNLDVIIIDTSGRHALEGDLIDEIKAVSKIANPSERILVLDAS
                     VGQQAGPQAQAFHDAVGVTSVILTKMDGTAKGGGALSAVSRTKAPIVFIGVGEHLEDL
                     DPFVPSRFISRLLGMGDLQSLMETAKESITEEQALETTKKIMSGRFSLKEMYEQMEML
                     TSMGPLKKLMGMLPGMGGGLQDKVNIEETQERLRRFRIIMDSMTDEEMENPKL"
BASE COUNT         1233 a         1398 c         1561 g          973 t
ORIGIN      
        1 atgtcgttgg acgtcgcccc gagatgaacg taattgccgg cggtcccgca cttttccgat
       61 agtgctttga ctaccgccat cacatcgtgc ttggtctccg cctcgatctc gtagaccctc
      121 tctctcgtaa ctatatcaat ggaagcggcg caggtgatct ccctggcagc ggagcgtggg
      181 atgtttccgg ccttggcgtg agcccgggct agcgcggcct cgaccttcag ctggaggtcg
      241 atcctgtggt cctcggagaa tatcgtcttc atctccttgc gcccgtaacg gaaatctaat
      301 ggacagatca gcattgaacg caccgtatgc gaataggatt ctgtgatgaa gctcttgaca
      361 tataagctta ctattgtcga aaatacgcta tttttgataa ttgaagggtt atggttaata
      421 tgccccatcc ggatgtattc gccaggtgtg atgtgagcgc gacgaacgca ggggctctgc
      481 cccgggagat catcgacttc ctgctatcgc cgggaggaca ttcgcttctg atcaagggag
      541 acgccggcac tggaaagacc actatggccc tgcagaccat agaggccctg tccgacaggc
      601 agcccgagta ctacctgtca tcgcgcgtat ccgacgtcgc gctctatcat cagttcccct
      661 ggttgaagga aagggtcgag aagaaccagc tcatgaaggc cggaatggcc tttctaagac
      721 gatcatggaa cagcgacggc tccaagagga acgccctgga ggacgcggaa ctgcgggtcg
      781 aacgccgcga gctcaatcgt ctggaggggc agatcgaggc cggcgagcta ggattggagg
      841 acgaggaagg cccgtccctg aacgccgacg gctccctgac cgtggaggtc ggctccatcc
      901 ttcccgagct ggagatggcc tatgatatcg ccgagagcaa cctacccaag aaaacgctgg
      961 tggtgctgga ttccgtggag gcgttggcgg agaactacgg cattccggca tatcgaataa
     1021 tgaacgctct gcagaaggac ctggtagaga aggccggcac caatgtcgtt ttcgtcatgg
     1081 agaccgccga gcgcagccac cttgattatc tgggcgacgg catcgtcgtc ctgcgcaata
     1141 ccgttcacgg caacaaccgg gtaaggacga tagagataga gaagttacgc ggatcctcca
     1201 ttcagaactg gaagtacctg ttcaccctgc agggcggacg ggtgaccgtg gtcgagcggg
     1261 acctggacct acgcggcgtg cagctttcga ggaaccagat ggaacttccg gccgggcgcg
     1321 gctcgttcgg ctggtcggag ctggaccgtc tgttcggagg agcgcccctc ggttcattga
     1381 cgctggtgga gatgggcgca ggcattccga tggacctctt ggagcggatc gaggtctcac
     1441 tggtcgaaga gcaccttcgg caaggccgag gcgtgctgtg gtatccgcag cgcaccctcg
     1501 atcacagttc cacacaaggg atcatgccag gtacatcgct tgaaacgttg cacgtcctgg
     1561 accccagtga ggcaagcgga tcatggcctt tcgtgaagaa gctggaaggg accgacctgg
     1621 cgaatgatct ccgttgggac tccctgaagt atctgctcaa gggctcccag gaaccttacc
     1681 tatcagtgct gggattggac gccctggaat cggtatacgg caaggttgtc cccaagctga
     1741 tgcagcatgt cgacctgatg cgccgcggcg gccacatggt agtattggag gccacggatg
     1801 gctcggccgg tctggagacc ttgagccacc aggcccggtt gcatctacgc ctggagaacc
     1861 tgaacggctc ggtgctgctg cggggaataa aaccaactac catctcttac tgcctggaca
     1921 tgacggatgg agtaccgctc tggaagccga tgctctgacg ttatcagccc tgatatccgg
     1981 gaaaagggga ttatatttcc gcggatgcgt gcattaagca tggcgaaaag cgccctgaaa
     2041 ctttcgagac ttctggcgga cgagtactcc ggccgcatct tgagcctcac cttctcccaa
     2101 ccccgttccg ttcaggagat ctgcgccctg tccggaattc cgatagccgt ggcgtatcgc
     2161 cggatcatag ccctggaagc ctccgggctg ataaagtgcc ttcggacgga agtttcgccg
     2221 accggtaaga gatgcaagta ctacatatgc caggtggacg tggcccgttt gaccttcaag
     2281 gaagggcgct tcgaggtcga ggtggagtgg agggaccata tgagagcgga tgccatccgg
     2341 gtcctggaat gacctccgca acagttttta tctgtgtagc acggtgaagg accttagatg
     2401 gggaaggaag acctgctggg caagtcccgg ttgcttaccg atgaatacgc ggtcaagatc
     2461 ctgacggcca cggtacgtac tcctcgtagc gcccagcaga tatccgccca gttcgggata
     2521 cctatcgccg cgtgctaccg gcgcatacgg gacctggagg tggccggcct catacgttgc
     2581 accgagcgcc gattgtccag gcaaggcaag cgggtctgct tctatcagtc caggatccga
     2641 accgcggcct tgcagtacga gaacggccgc ctaaaggtac gcttcaccat gctggacgaa
     2701 acccagaaca gcgactggca ggacgttgac ctccacgagg accggaacga tggcgacgga
     2761 agatgatccg atttcgatgc tggatagatt aaccggatta tcgaaaaagt tataaagagt
     2821 atctcttatg ccctttccag gcttgagtct tatttaattt gacatttgag cgtgaacgtt
     2881 tatgacagaa ctcttggagg acctcgacca gaagcgtcaa tttaacaaca acgaggcgga
     2941 gaagcaccgc cggctcaggg atgaactgaa cgacaagacc aaggaatggg ttcagaagag
     3001 ggacgaactc aactccaagg tccgtgagct ggtggacagt gctgcaaagc accgcgagaa
     3061 ccgcgacaag atgaacgaac aggtgcgagc cgccaaggac gcccgcgaca agttcaatga
     3121 acaggtcagc gagctcaaca agaaggtcat ggctttgaag aaggacaacg tcccgcaaga
     3181 gggaccgtcc gtcgccaagc tgaagaagga cctgaagcag ctcgagttca tccacatgac
     3241 ctccggagac ctgaagaggg acaaggagaa ggccttggta gagcagatga aggcgctcca
     3301 gatccagatc agggagaggg agaagtctct agaggccaac gacgaggtcc gcgaggcgat
     3361 cacgctcctg cgcgaggcca aggacaaggc cgaggagcag caccggctgg ttagcgaact
     3421 ggccgagggc gcccagaacg cccacgactc catgatcaag atctacgaag aggcggacaa
     3481 gctcagaaag gaagctgacg aggcccagga aaagttcatc gagaccaagg gcaaggccga
     3541 cgaagagcac cgccgtcaca tagacaacat caggcaggtg cacgattacg acaagatcat
     3601 caccggccta aggcagaagg cccgcaaggc ccgcaagaag aaggacgaga gcgtagccat
     3661 gaaggaatct gaggagatct tcgacaagtt caagcgcgga gagaagctca gcaccgagga
     3721 cctcatggta ctgcagaagt ccggctatct gtaaaccact taacacaaca tattctttaa
     3781 acaactggct gctggccgcg gccggttttt tccctgtttt ttaaaataat ggaaacctat
     3841 atatatcgtc gaaaagatag tagaggtcgg gaaggtctgg gctggttttc agagtgcatc
     3901 ccatcccttc tgacaggact ggtccttccc aaaccccttt ttctacctct tcttgtagca
     3961 aaggttatct aactccgtcg gattgtcaat gaaggtctga acatggtatt ggaaggattg
     4021 ggccaatcac tgcgtgacgt cctgaagaag gtcgccaact ccagcaacgt ggacgacaag
     4081 ctgatcaagg aggtgtccaa ggacatacag agggcgctcc tgcaggccga cgtcaacgtg
     4141 aagatggtcc tggagataac caaggaggtg gagcgccggg cgctcaccga gaagcctccg
     4201 gccggcaagt ccgggcggga gcatgtcatc aagatcattt tcgacgaatt ggtgaagatc
     4261 ctgggcgagc agaggacact gccgctgggc aagcaggtca tcatgatggt cggtctttac
     4321 ggtcaaggaa agaccaccac cgcaggcaag ttaggacgtt actttcacaa gaaggggctc
     4381 aaggtcggcc tcatagccgc ggacgttcat cgaccggccg cttacgacca gttgaagcag
     4441 atcggcgaca agatcggcgt tcaggtgtac ggttcaccgg ccgaacggtc ggcggtcaac
     4501 atcgtcgaga ccggaatgaa gcagttcagc aatctcgacg tgataataat cgatacttcc
     4561 ggacggcacg ctctggaagg cgacctcatc gacgagatca aggcggttag caagatcgcc
     4621 aatccctcgg agaggatact ggtcctcgac gccagcgtgg ggcagcaggc cggaccgcag
     4681 gcccaggcct tccatgacgc ggtcggggtc acttcggtca tacttaccaa gatggacggc
     4741 acggccaagg gcggcggcgc tctttccgcc gtctcccgca ccaaggcgcc catcgtgttc
     4801 atcggagtag gcgagcacct ggaagacctt gatccgttcg taccgtcgcg cttcatatcc
     4861 cggctgctgg gaatgggcga cctgcagtcc ttgatggaga cggccaagga atccatcacc
     4921 gaggagcagg ccctggagac caccaagaag atcatgtccg gccggttctc cctgaaggag
     4981 atgtacgagc agatggagat gctcaccagc atgggtcccc tgaagaagct catgggcatg
     5041 ctgccgggca tgggcggagg attgcaggac aaggtcaaca tcgaggagac gcaggagcgc
     5101 ctgcgccgct tccgcattat catggactcc atgaccgacg aggagatgga gaaccccaag
     5161 ctcat
//
LOCUS       DAOPZI010000052         4679 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_23437_length_4679_cov_10.219291, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000052 DAOPZI010000000
VERSION     DAOPZI010000052.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 4679)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4679)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4679
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_23437_length_4679_cov_10.219291"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..3089)
                     /gene="carB"
                     /locus_tag="PKM11_07760"
     CDS             complement(<1..3089)
                     /gene="carB"
                     /locus_tag="PKM11_07760"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HNX48436.1"
                     /translation="MSKGKLLVIGSGPIVIGQAAEFDFSGSQACRSLREEGYTTVLVN
                     SNPATIQTDLEMADIVYIEPLNVETIAEIIRKEKIEGVLSGMGGQTALNLCSELADKG
                     YLEKLNCRLLGTQPRAIALSEDRELFRETMLEIGEPIPRSVTVTNIDDAKKAVEAIGG
                     YPALIRPAYTLGGTGGGIAYNEDELIPITGRGLIYSRIRQVLIEESVLGWKELEYEVM
                     RDKKDNCIIICTMENLDAMGVHTGESIVVAPLQTINDEDHQRMRTASIKIIRALGIEG
                     GCNVQFAYNPANREYRVIEVNPRVSRSSALASKATGYPIARVAAKIAVGKTLDEIPNK
                     ITGQTYAAFEPSIDYVVAKIPRWPFDKFRTVETKIGTQMKSTGEVMSIGRTIEESLMK
                     AVCSLETDRIDLEPEVWNDKELEAELVAPSDKRLYAIAEAIRRNMTVEKIADLTKWDA
                     FFVRKIANIVKMEKELAAGPLTPELIRRAKRMGFQDESIGKFAKRSEASVRQTRKENG
                     ILPTYKMVDTCAAEFAAQTPYFYSTYGTECEVPKSDNKKVIIVGAGPIRIGQGIEFDY
                     CCVHGVMACQAAGVDAVVINNNPETVSTDYDISDRLYFEPLTLEDVMNVIEKENADGV
                     ILQFGGQTSVNLAVPLEAALKGHKCKVLGTSPDMMDMAEDRKRWSALMKELNIAQPES
                     GTGHSYEEVKAHADRIGYPVLLRPSYVLGGRGMEIIYTEDELKQYVATAVKVSKKHPV
                     LIDKYLTHARELDVDVVCDGKDVFIGGIMEHIEEAGVHSGDATMVLPCQTISPEIMKR
                     VVEITNVVALALQIKGSMNLQLAVKDDEVFMLEANPRASRTVPFISKAIGVPLAKLAT
                     KVMLGETLKDLGYVGVAKFEHVAVKASVFPFLKLVGVDSILGPEMKSTGEVMGIDKYY
                     GAAMYKAMISAGNKLPLQGGVYVTVSDADKAGILPLVTELHEMGFTIYATKGTSTFMR
                     NNGVPVTTVYKVAENVSPDALGLMRRGEINLIINTPTYSSGSRRDGYMMRRLAVELE"
     gene            complement(3086..4165)
                     /gene="carA"
                     /locus_tag="PKM11_07765"
     CDS             complement(3086..4165)
                     /gene="carA"
                     /locus_tag="PKM11_07765"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005951 - carbamoyl-phosphate synthase
                     complex [Evidence IEA];
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HNX48437.1"
                     /translation="MAKCFLVLEDGTIMEGTGFGSLENTSGEVVFSTGMTGYQEGLTD
                     PSFRGQILTMSYPLIGNYGVNPKDMESERVQVRGFVVRDLCENPTDLYGGKTLDSFLI
                     ENGIPGIAGVDTRSLIIRIRNAGTMRGAIVYDGDPAGHLEEIRAMPYPSELGLVKDVS
                     TPKVLHYPKSGAKKVAIFDCGVKRSMVDELRKRFEVYQLPYDTGIDFFRNTEIDGLFL
                     SNGPGNPAHPTLKESVISTVRKLKDDYPIMGICMGNQLLCQVFNGSTYKMKFGHRGAN
                     QPVRYKDRVFITSQNHGFAVDPETLEGSGLEVDQVNVNDGSVEGMRHRELPIFSVQYH
                     PEARPGPTDTGFLFDDYAKMLEARK"
     gene            4345..>4679
                     /locus_tag="PKM11_07770"
     CDS             4345..>4679
                     /locus_tag="PKM11_07770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mRNA surveillance protein pelota"
                     /protein_id="HNX48438.1"
                     /translation="MKVLHQDRFKGEIKMQVEVSDDLWHLYNILTPGDLVFSSTYRRE
                     ETKSDKIRAERGEKKRMTLGIRLEKVEFGEFDNRLRLLGVIEEGPQDVGSYHTLIMEE
                     GEVLSIIKQ"
BASE COUNT          897 a         1364 c         1349 g         1069 t
ORIGIN      
        1 atctccaatt ccaccgccag tcgcctcatc atgtatccgt cgcggcgcga gccggaggag
       61 tacgtcggag tgttgatgat caggttgatc tctccgcggc gcatcaggcc aagcgcatca
      121 ggcgagacgt tctccgccac cttgtagacg gtggttacgg gaacgccgtt gttgcgcatg
      181 aaggtggacg ttcctttcgt ggcgtagatg gtgaatccca tctcgtgaag ttcggtcacc
      241 aacggcagta tgcccgcctt gtcggcgtcg gaaaccgtaa cgtaaacgcc gccctgcaac
      301 ggcagcttat tgcccgcgga tatcatggcc ttgtacatcg cggcgccgta gtacttgtcg
      361 atgcccatga cctcgccggt gctcttcatc tccggtccca ggatggagtc gacccctacc
      421 agtttgagga acgggaagac ggacgctttt accgcaacat gctcgaactt tgccacgccg
      481 acataaccga ggtccttcag cgtctcgccg agcatgacct tggtggccag cttcgccaac
      541 ggtacaccta tggccttgga tatgaacgga acggtgcgag acgctcgcgg gttcgcctcc
      601 agcatgaaga cctcgtcgtc cttcaccgcc agttgcaggt tcatgctgcc cttgatctgc
      661 agcgctaacg caacgacgtt ggtgatctcg acgacccttt tcatgatctc cggggagatg
      721 gtctggcacg ggagcaccat ggtcgcgtcg cccgaatgaa cgccagcttc ttcgatgtgc
      781 tccattatgc cgccgatgaa cacgtccttt ccgtcgcaga cgacgtccac gtccagttcc
      841 ctggcgtgcg tgaggtactt atcgatgagc accggatgct tcttggatac tttaacggcc
      901 gtagccacgt actgcttcag ctcatcttcc gtgtaaatga tctccatacc gcgtccgcct
      961 agcacgtacg acggccttag gagcacagga taaccgatgc ggtcggcatg ggccttgacc
     1021 tcttcgtaag agtgtccggt accggactca ggttgagcga tgttcagctc cttcatgagc
     1081 gccgaccagc gcttgcggtc ctcggccatg tccatcatgt ccggcgatgt gcccaggacc
     1141 ttgcacttgt ggcccttgag cgccgcttcc aatggaacgg cgagattgac cgaggtctgc
     1201 ccgccgaatt gcagtatgac gccgtccgcg ttctccttct cgatgacgtt catgacgtcc
     1261 tcgagggtga gcggttcaaa gtacaggcgg tcggagatgt cgtaatcggt ggaaaccgtc
     1321 tccggattgt tgttgatgac caccgcgtcg acaccggcgg cctggcaggc catgaccccg
     1381 tgcacgcagc aataatcaaa ttctatgcct tgaccgatac gtatcggtcc ggcgccgact
     1441 atgatgacct tcttgttatc ggacttggga acttcgcatt ccgttccgta cgtcgagtag
     1501 aagtaaggcg tctgggcggc gaactcggcg gcgcaggtgt ccaccatctt gtaggtcggc
     1561 aggatcccgt tctccttcct ggtctgcctc acggacgctt cggatctctt ggcgaacttg
     1621 ccgatgctct cgtcctggaa gcccatgcgc ttggcgcgac gaataagctc aggcgtcagc
     1681 ggtccggcgg ccagttcctt ctccatcttg acgatgttcg ctatctttcg cacaaagaac
     1741 gcgtcccact tggtgaggtc ggcgatcttc tccacggtca tgttccggcg tatcgcttcc
     1801 gcgatggcgt aaaggcgctt atcggaggga gcgacgagct ccgcttccag ctccttgtcg
     1861 ttccatactt ccggttcaag gtcgatgcgg tcggtctcca acgaacagac ggccttcatc
     1921 agcgactcct cgatggtgcg gccgatggac atgacctccc cggtgctctt catctgggtc
     1981 ccgatcttcg tttccaccgt ccggaacttg tcgaagggcc agcgcgggat tttagccacg
     2041 acgtaatcga tgctcggctc gaaggcggcg tacgtttgac cggtgatctt gttcgggatc
     2101 tcgtccaacg tctttccgac cgcgatcttg gcggccaccc tggctatcgg gtagccagtt
     2161 gcttttgagg ctagggcgga agaacgggag acacgcgggt tgacctcgat gacccggtac
     2221 tccctattag cggggttgta ggcgaactgc acgttgcatc ctccctcgat ccccagagca
     2281 cgaatgatct tgatggacgc ggtgcgcatc ctctgatggt cctcgtcgtt tatcgtttgc
     2341 agcggggcca cgactatgga ctcgccggtg tgcacgccca tggcgtccag gttctccatg
     2401 gtgcagatga tgatgcagtt gtccttctta tcccgcatca cctcgtactc cagctccttc
     2461 cagccgagca cgctctcctc gatgagcacc tggcgtatgc gcgagtagat caatccgcgg
     2521 ccggttatgg gaatcagctc atcttcgttg taggcgatgc cgccgccggt cccgcccagg
     2581 gtgtaagctg gacgaatgag ggccgggtat ccgccaatgg cctccacggc cttcttggcg
     2641 tcgtcgatgt tggtgacggt gaccgaacgc gggatgggct cgccgatctc gagcatggtc
     2701 tcccggaaca gctcgcgatc ctcggataag gcgatagcgc gcggttgcgt cccgagcaga
     2761 cggcagttca gcttctccaa gtatccttta tcggccagtt ccgagcagag gttcagggcg
     2821 gtctgcccgc ccatgccgga gagcacgccc tcgatcttct ccttacgaat gatctcggcg
     2881 atggtctcta cgttcaacgg ctcgatgtaa acgatgtcgg ccatctccag gtcggtctgg
     2941 atcgtcgccg ggttggagtt tacgagcacg gtcgtataac cttcctcgcg gagggaacga
     3001 cacgcttgag agccggagaa gtcgaattcg gcggcttggc cgatgacgat gggcccggag
     3061 ccgatgacca gaagcttccc tttgctcatt tcctcgcctc cagcatcttg gcgtaatcgt
     3121 caaagaggaa tccggtgtcc gtcggtcccg gccgcgcttc agggtgatat tgaacggaga
     3181 atatcggcag ttcccggtgg cgcatgccct ccacggaacc gtcgttcacg ttcacctggt
     3241 caacttccag tccagagcct tcgagcgttt cagggtccac ggcgaagccg tggttctgtg
     3301 aggtgatgaa gacccggtcc ttgtagcgta ccggttgatt ggcaccgcgg tgcccgaact
     3361 tcatcttgta ggtgcttcca ttgaagacct ggcagagcag ctggttgccc atgcatatgc
     3421 ccatgatcgg ataatcatcc ttcagtttcc gaacggtgga gataaccgat tccttgagcg
     3481 tgggatgagc cgggttgccc gggccgttgg acaggaacaa tccgtcgatc tcggtgttgc
     3541 ggaagaaatc gataccagta tcgtacggta attggtatac ctcgaagcgc ttgcgcagct
     3601 cgtcgaccat ggaacgtttt acgccgcagt cgaaaatggc caccttcttg gcgccgctct
     3661 tcggataatg aagcaccttg ggggtgctga cgtccttgac cagtcccagt tcggacggat
     3721 agggcatggc gcgtatctcc tccagatgcc cggccggatc gccatcgtag acgatggcgc
     3781 ctctcatggt tccggcgttt cggatcctga tgatgaggga acgggtgtcc accccggcta
     3841 tgccagggat cccgttctcg atgagaaatg aatctaaggt cttgccgccg taaaggtcgg
     3901 tcgggttctc gcaaagatcg cgaactacga atcctcgaac ctgcaccctc tcggactcca
     3961 tgtccttagg gttaacacca taattaccga tcaacgggta ggacatcgtc agaatttggc
     4021 cgcggaatga ggggtcggtc aggccttcct gatagccggt catgccagtg ctgaagacca
     4081 cctcccccga ggtgttctcc agggaaccaa atcctgtgcc ctccatgata gtcccgtcct
     4141 cgagaaccag gaagcacttt gccatcagaa ttccacggta gtattgtagg atacttaatg
     4201 attactgaac aatcgaaccc cactggtacc cttttgtctg gatgcctaca gtcagtcaag
     4261 aattgcgaat aaacgacctt cgttttgtct aatttcggac gctttgggac aaccataaat
     4321 gcccggtagg gcatgaccac ggcgatgaag gtactgcacc aggaccgttt caagggggag
     4381 atcaagatgc aggtggaggt gtccgatgac ctttggcacc tgtacaacat cctgacccct
     4441 ggggacctgg tcttctcctc cacgtaccgc cgcgaggaaa ccaaatccga taagatcagg
     4501 gcggagcgtg gcgaaaagaa acggatgacc ctagggatcc gcttagaaaa ggtggagttc
     4561 ggggagttcg ataatcgatt acggttattg ggcgtcattg aggaaggtcc gcaggacgtc
     4621 ggttcctatc acaccctgat catggaggag ggcgaggtgc tctccataat caagcagca
//
LOCUS       DAOPZI010000053         4676 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_23462_length_4676_cov_8.233283, whole genome shotgun sequence.
ACCESSION   DAOPZI010000053 DAOPZI010000000
VERSION     DAOPZI010000053.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 4676)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4676)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4676
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_23462_length_4676_cov_8.233283"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..899
                     /locus_tag="PKM11_07775"
     CDS             <1..899
                     /locus_tag="PKM11_07775"
                     /inference="COORDINATES: protein motif:HMM:NF025877.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Wzt carbohydrate-binding domain-containing
                     protein"
                     /protein_id="HNX48439.1"
                     /translation="MDDLVPLIVEFADIGEFIDQPVKTYSSGMFVRLAFALAINVDPD
                     ILIVDEALSVGDIYFQAKCYRKFEEFKNVGKTILFVTHDMNSVLKYCDRAMVLDHGDK
                     IGEGTAKEMVDLYKRTVAGSNGAKDGSVVAAKLSDGLWRDKVVVNTAALDYGDGAIKI
                     TDFGAFDENGILSQSILKGNGFSIRMRLTVRSEVPDPIFAMTIKDVKGNELTGTNSKL
                     EMKDPGPVRQGDEFVVEFRAPMLLQGGQYLISLGCTSYDPSGELVVHHRLYDIFSVYV
                     VASKFVVGAFDMGFDMSVERSN"
     gene            990..1895
                     /locus_tag="PKM11_07780"
     CDS             990..1895
                     /locus_tag="PKM11_07780"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF024880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HNX48440.1"
                     /translation="MGIMQGGPRLILDHVNGTEDYSDGDVEEDLLSLVSAGKDLEEAV
                     HNDDRWPVLYHFHPKRRNLLEWFPFKKEASLLEIGAGCGALTGMLCEKVEKVTAIELS
                     ERRAKIIAARYPRSHNLTIYAGRFEDVPLTEDYDYVTLIGVLEYAGRYARSTDPYSDL
                     LRRARNSLKKDGKLILAIENKLGLKYWAGAPEDHSGQLFQSLEGYPDEKGFRTFGRQE
                     LIALLNGSGFKETEFLYPYPDYKMPDRLYSDRFLPRPGEMSKGSPSYDQERFTLFDEG
                     LAYDNILTNNAFPLMANSFLVICGL"
     gene            1897..4422
                     /locus_tag="PKM11_07785"
     CDS             1897..4422
                     /locus_tag="PKM11_07785"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX48441.1"
                     /translation="METFNVDFVKYNRERLPQYRTETSVLSSDTERWVIKRALTAEGM
                     PHVLNMVKGANLLRTLLRNANVPVTVPVEGGVRIDYIDGRSIEDELVGLAMRGDREGF
                     VEAIQMFRTFLETLGLTGKAEMNGTVKELLAGVPDSVGELMPVANLDLTFDNVIVDGD
                     GRRWITDQEWVFDSPVPISFLMYRSLYVMYLKNERRLGIITFPEALIEAGVPEELWEP
                     YQHSCERFIDLVLGKDRPHLIPSSYIKAERRLADRDLLESREQQLYAAQLELEATKGA
                     LAEMMAHAKVREERLQEQERRLGVMTDEMEGAKASLAEREGRLESLRIDLESLRIDLE
                     SERLRNAAAQAQLELERGQRDEIFAHLQDMNEKFMSKQAELMTMSDWARSMQLRLEFM
                     ESIPTIRVAERVAKVQKLGVEKLRSEGLIRTMKDLAFSYSPQQLQQMFYHQEASNIKD
                     LMDDASGRNVLVVFPVIPWEFRWQRPQQLVSRFAENGYTVIFVNMTLTAKGARYLSNA
                     EALKDVKLGKLRDHVFEVHLSTQNKINVYQDQIKGGDLNNLGYGLLSVLRELEPASVT
                     YLVQFPGWGQLANVARSRIGGTLVFDCMDDHAGFSNNSTEVVKRETMLMESADLVVTS
                     SAKLYDKALAFNDNSILVRNGTDFEMFRTLFPNGKLDSLKGPIIGYHGAISEWFDPGV
                     VQRCAEKHPEWNFVLIGSTLGCEVNGLKKLTNVQLLGEMPYKDLPGYLYYFNVCIIPF
                     RVCELTLATNPVKFYEYISSGKPVVSVKLPEMEQYADVCYLYETDEEFERGIVTALAE
                     KDEELRNKRIEVARRSSWDQRFQDVNEHLKKMSEGQSSKRKVL"
     gene            4450..>4676
                     /locus_tag="PKM11_07790"
     CDS             4450..>4676
                     /locus_tag="PKM11_07790"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012745.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX48442.1"
                     /translation="MRASVVVLTYNQLQEGTKPCLESILLYTPKDQFELVIVDNASSD
                     GTPDHLRKVAQEHDNVTLVLNSENKGYAGGN"
BASE COUNT         1093 a         1256 c         1431 g          896 t
ORIGIN      
        1 ccatggacga tctcgttcct ttgatagttg agttcgcgga catcggggag ttcatagacc
       61 agcccgtgaa aacatacagc agcggcatgt tcgtgcgctt ggccttcgcg ttggcgatca
      121 acgtggaccc ggacatcctc atcgttgacg aggcgctcag cgtcggcgac atctacttcc
      181 aggctaagtg ctatcgcaag ttcgaggagt tcaagaacgt cggcaagacc atcttattcg
      241 tcactcatga catgaactcg gtgctgaagt actgcgatcg ggccatggtc ctggaccacg
      301 gcgacaagat tggcgaaggt accgccaagg agatggtgga cctctacaag cgcaccgtgg
      361 ccggatccaa tggggcgaag gatgggagcg tcgtagcagc gaagctgtcg gacggtttgt
      421 ggcgggacaa ggtcgtcgtc aacaccgccg ccctggacta cggggacggc gctatcaaga
      481 tcaccgattt cggggccttc gatgagaacg ggattctatc acaatccatc ctgaagggga
      541 acggtttctc catcaggatg aggttgacgg ttagatcgga ggtgcctgac cccatattcg
      601 ctatgaccat caaggacgtc aaggggaacg agctaaccgg caccaactcc aagctggaga
      661 tgaaggaccc tggaccggta agacaaggtg acgagttcgt ggtcgagttc cgcgcgccca
      721 tgctcctgca gggcggacaa tacctgatat cgctgggatg caccagctat gacccgtccg
      781 gggagctggt ggttcatcac cgcctctacg acatattctc agtgtacgtc gtggctagca
      841 agttcgtggt gggcgccttc gatatgggtt tcgacatgag cgtcgagcgg tccaattgaa
      901 cagatgacga tgccagtgat aaaaaaaccg gttcaataag tttaaatcgg cacagcgatt
      961 aaacattgca ataaagccta aggctggcga tgggaataat gcagggcgga cctagactga
     1021 tcttagacca cgtcaacgga acagaggatt attccgacgg ggacgtggag gaggacctcc
     1081 tctccttggt ctccgcgggc aaggacctgg aggaggcggt ccacaacgac gaccgttggc
     1141 cggtgctcta ccatttccat cccaagcgcc ggaacctgct ggaatggttc ccgttcaaga
     1201 aagaggcgtc actgttggag ataggagccg gatgcggggc gctcaccggc atgctctgtg
     1261 agaaggtcga gaaggtcacg gccatcgaac tttccgaaag gagggccaag ataatcgccg
     1321 cccgctatcc aaggtcacat aaccttacca tatacgccgg gcgattcgag gacgttcctc
     1381 tcacggaaga ttacgattac gtcactctta tcggagttct agagtacgcc ggtaggtacg
     1441 ccaggagcac cgacccctac agcgatttgc tgcgtagggc gcgaaattca ctaaagaagg
     1501 acggaaagct catcctggcc atcgagaaca agctcggcct caagtactgg gccggggcgc
     1561 cggaggacca ttcgggccaa ctgttccaaa gtctggaggg ctatccggac gagaagggtt
     1621 tccgtacctt cggacgacag gaactgatag ctttgctgaa cggttccggc ttcaaggaaa
     1681 cggagttcct gtacccctac cctgactaca agatgcccga tcggttgtac tcggaccgat
     1741 tccttccccg cccgggtgag atgtcgaagg gatcgccaag ctacgatcag gagcgtttta
     1801 cgctattcga cgagggactg gcctacgata atatattgac caacaacgcg ttccccctga
     1861 tggcgaactc gttcctagtg atctgcgggc tttgacatgg aaacatttaa tgtcgacttc
     1921 gtgaagtaca atcgggaaag gctcccccag taccgcacgg agacctccgt cctttcctca
     1981 gacacggaac gttgggtgat caagagagcg ttgacggctg agggcatgcc tcatgtcctg
     2041 aacatggtca agggagctaa tcttctacga actttgctcc gaaacgcgaa cgtcccggtt
     2101 accgtcccgg tggagggcgg agtgcgcatt gactatatcg acggcaggtc gatcgaggac
     2161 gaactggtcg gtttggccat gcgcggagat cgggaaggct tcgtggaagc gatccagatg
     2221 ttccggacct tcctggagac gctcggttta accggcaaag cggagatgaa cggcacggtc
     2281 aaggagctgc tggcaggcgt tccggacagt gtgggagagc tgatgccagt ggccaatctc
     2341 gacctcacct tcgataacgt cattgtggac ggggacggga gaagatggat caccgaccag
     2401 gaatgggtgt tcgattcccc cgtgccgata tcgttcctca tgtaccgcag cctgtacgtg
     2461 atgtacctga agaacgagag aaggttgggg atcatcacat ttcctgaggc gctcattgaa
     2521 gctggcgtcc ctgaggaatt atgggaaccg tatcagcact cctgcgaacg gttcatagac
     2581 ctggtgctgg gcaaggatcg cccacatctc attccttcaa gctacatcaa ggcggagcgc
     2641 cgcttggccg accgggacct gctggagagc cgggaacagc agctgtacgc cgcccaatta
     2701 gaactggagg ccaccaaggg cgccctggcg gagatgatgg ctcacgcaaa agttcgggag
     2761 gaacgcctgc aggagcagga gaggcgcctg ggcgtcatga ccgatgagat ggagggcgcg
     2821 aaggcctccc tggccgagag ggaaggtagg cttgagagct tgcggataga cctagagagc
     2881 ttgcggatag acctagagtc cgagcggctg cgcaacgcgg ccgcccaggc ccaattggaa
     2941 ctggaaaggg gccagcgtga cgagatcttc gctcacctgc aggacatgaa cgagaagttc
     3001 atgtccaagc aggcggaact gatgaccatg tctgactggg cgcgcagcat gcagctccgc
     3061 ctggagttca tggagagcat cccgaccatc agggtcgccg aacgagtggc caaggtccag
     3121 aagctgggcg tggagaagct gcgctcggaa gggcttatac gaacgatgaa agacctggcg
     3181 ttcagctact cgccgcagca gctccagcag atgttctatc atcaggaggc ctcgaacatc
     3241 aaggacctca tggacgacgc ctccggcagg aacgtgctgg tggtgttccc ggtgatcccg
     3301 tgggagttcc gctggcagcg gccgcagcaa ctggtctccc gtttcgccga gaacggttac
     3361 acggtcatct tcgttaatat gaccctgacg gccaagggag cacgctatct gagcaacgcg
     3421 gaagcgttaa aggacgtcaa gctgggaaaa ttgcgcgacc atgtcttcga ggtgcatctc
     3481 agcacccaga acaagatcaa cgtctaccag gaccagatca agggcgggga cctgaacaac
     3541 ctggggtatg ggcttctctc ggtgctgaga gagctggagc ccgcgtccgt tacgtacctg
     3601 gtgcagttcc cgggctgggg acagttggct aacgtggcca ggtcccggat cggcgggacc
     3661 ctggtgttcg actgcatgga cgatcacgcc gggttcagca acaactcgac ggaggtcgta
     3721 aagagagaga ccatgctcat ggagagcgcc gacctggtgg tcaccagctc cgcgaagctg
     3781 tatgacaagg cattggcgtt caacgacaat tccattcttg tccgaaacgg aacggacttc
     3841 gagatgttcc gcaccctttt cccgaacggc aagcttgatt cgttaaaggg accgataatc
     3901 ggctatcacg gcgccatatc cgaatggttc gatcctggcg tcgttcagag atgcgctgag
     3961 aagcacccgg agtggaactt cgttctgatc ggttccacgc tcggctgcga ggttaacggc
     4021 ctcaagaaac tgacgaacgt acagctcctg ggagagatgc cctacaagga cctgcccggt
     4081 tacctttact actttaacgt ctgcatcatt cccttccgcg tctgcgagct gaccctggcc
     4141 accaatccgg tgaagttcta cgagtacatc agcagcggca agccggtggt aagcgtcaag
     4201 cttccggaga tggagcagta cgcggacgtc tgctacctct acgagacgga cgaggagttc
     4261 gagagaggga tcgttaccgc tttggccgag aaggacgagg agctacggaa caagcggata
     4321 gaggtcgccc gcaggagctc ctgggaccag cgcttccagg acgtcaacga gcacctcaag
     4381 aagatgtccg aaggccagag cagcaagcga aaggttctat aggccaggca ttcattcgag
     4441 gaggtctata tgcgagcaag cgtcgtggtc ctgacctaca atcagctcca ggaaggcacc
     4501 aagccctgcc tggagagcat tcttctgtac acgccaaagg accagttcga gctggtgatc
     4561 gtggacaacg cctcatcgga cggaacgccg gaccatttgc ggaaggtcgc tcaggaacac
     4621 gataacgtga cgctggtcct caactcggag aacaagggat acgccggcgg caacaa
//
LOCUS       DAOPZI010000054         4386 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_25809_length_4386_cov_8.936042, whole genome shotgun sequence.
ACCESSION   DAOPZI010000054 DAOPZI010000000
VERSION     DAOPZI010000054.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4386)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_25809_length_4386_cov_8.936042"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(264..770)
                     /locus_tag="PKM11_07795"
     CDS             complement(264..770)
                     /locus_tag="PKM11_07795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HNX48443.1"
                     /translation="MDVTGAIKARRSIRKFNRKEIPSELLEHMLEMARIAPSGANRQP
                     WEMVVITDRQRLKDLVPICKDQSFVGDCSAFLVGIDDPQQKWAKVDLTIALDHLTLAA
                     VDEGLGTCWIGAFDQTRMAEFIGLPADRTITVCLALGYPEETPAARGRKKTEDLFFWD
                     RYGERDRP"
     gene            complement(826..2370)
                     /locus_tag="PKM11_07800"
     CDS             complement(826..2370)
                     /locus_tag="PKM11_07800"
                     /inference="COORDINATES: protein motif:HMM:NF013117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HNX48444.1"
                     /translation="MRSRTVLNLAGLMLLGLLVFTAAFAPTASAGQVNAFMVGQDELT
                     TVAGTPASFEWILYNNDTVPYVITPSSDQTSNAEFSVDFDQSYLTLYPGESESIIMTV
                     TTVREMPESATVFEVRFNITQMNELGNTFSISDTVRLDVVPVFGAGAGDNKILGIWDN
                     NLPWPLDGNAGAFVVSVGIWAVIALFVILVADPLLHRLTSKTATELDDIILRIIRGPV
                     LLLMVLYGAVRSLEILNLNRVLIADLELAYSVAFILAIAWLSYKIYAGVIVFYGHKLA
                     AKTDSEVDDVLVPIFEKLGMIVIPIIALAVILGLFGYNLTVILAGLGFMGIVIGYAAQ
                     ATLANFFAGMQMMFDRPFKLGDLLRLDNGDICEVRHIGMRATELYNTFTNEMVIVPNN
                     DIANKKIVNMVQPDRRLKIAVGVDVAYGSDVDLVLRLMKEAAQSLPEVMNDPDHETVV
                     RFSDFADSSLKFTAFIWVVDLDLQFKVASDYRAELLRRFDNNGIEIPFPQSVVWLRDL
                     SKAEGD"
     gene            2469..3350
                     /locus_tag="PKM11_07805"
     CDS             2469..3350
                     /locus_tag="PKM11_07805"
                     /inference="COORDINATES: protein motif:HMM:NF018546.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HNX48445.1"
                     /translation="MEELTWARIALALAIMVAASVSDWRSRTASDVHWYILGIGGSIL
                     FGLQLFFDGAPWIFLVCLALMTLVFADLLWDRPGIFEDGVNVPPLVLYVLTFLAFGYL
                     SLEHFGEGRYWTMLSIPLLIVFFFVMYQLDVIKGGADAKALIALSLVFPIYPELSGLP
                     LLELNDPAALTILPFPVLVLFNGAILTLLVPVGMLLMNLVRRDLRFPSMLFGTRMTID
                     DARKKHVWPMERVADGKVKTVLFPRSDEEADWDALRQAGVDRPWVTPKVPFLIPLTLA
                     VPFSLLMGNILLYLMGA"
     gene            complement(3357..>4386)
                     /gene="amrS"
                     /locus_tag="PKM11_07810"
     CDS             complement(3357..>4386)
                     /gene="amrS"
                     /locus_tag="PKM11_07810"
                     /inference="COORDINATES: protein motif:HMM:TIGR04337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="AmmeMemoRadiSam system radical SAM enzyme"
                     /protein_id="HNX48446.1"
                     /translation="RDMSTSGTELKDALFWEREGNTLRCQLCPHSCLIKEGKTGICRV
                     RQNVDGTLKAISYGMVSSVHLDPLEKKPLFHFRPGEPVLSFGGLSCNLRCQHCQNFTI
                     AQVGLENGMSRYVPPEQVPEMCHKAGSNGVAWTYNEPTIWYEYMFESSRLCKERGLFT
                     VSVTNGFIQEEPLRSLRGVIDAMNIDVKGFTENFYGEVCKGSLAPVLRACEVAREIGI
                     HVELTYLIIPGKNDRRQEIADFCQWVRDSMGTQTPVHFSRFHPDYKMEDVPPTPRSTM
                     DLALKEGKAHGLDYVYVGNIATEKGENTYCPKCSSLLVRRSGFSAEIVGIKDRACSKC
                     GRPADIVW"
BASE COUNT          854 a         1300 c         1282 g          950 t
ORIGIN      
        1 ccacccagaa cagcaaggaa tggatgcgag agagtatctt gaccctctcc tctggactaa
       61 gacaatcctc ggcgcaaccg tactcggtca tcctgctgac ctccttggct tggtcaccgg
      121 acggaccgtc caggaagcgg agatgtcgtc gagggctcgg acaatggcac cgtaagccct
      181 taccattcct tggaggaccg gagcgaccgg cttgaacgct ttccgattcg ggtcgtgact
      241 cttcaggtcg agatcacgct cgctcatggc ctgtcgcgct cgccgtagcg gtcccagaag
      301 aacaggtcct ccgtcttctt gcggccgcgg gcggcgggcg tctcctccgg atagcccaag
      361 gccaagcaga cggtgatggt acggtcggcc ggcagtccga tgaactcggc catcctggtc
      421 tggtcgaacg ctcctatcca gcaggttcca agaccttcat ctacggccgc caacgtaagg
      481 tgatcgaggg cgatggtcag atcgaccttg gcccacttct gctgcggatc gtcgatgccc
      541 accaagaagg ccgagcaatc cccgacgaac gattggtcct tgcatatcgg caccaggtcc
      601 ttgagcctct gacggtcggt tatgaccacc atttcccagg gttgccggtt cgctccggac
      661 ggagcgatgc gggccatctc cagcatgtgc tccagcagct ccgacggtat ctccttgcga
      721 ttgaacttcc tgatgctcct acgagccttg atagcgcctg tgacgtccat tcgagcccca
      781 cctcgatgat atagacaatg cgttgagaag gcatatttct tctggtcagt ccccttcggc
      841 cttgctcagg tcccggagcc aaaccaccga ttgagggaac ggtatctcga tgccgttgtt
      901 atcgaagcga cggagcagct cggcacggta gtcggacgcc accttgaact gaaggtccag
      961 gtccacgacc cagatgaacg cggtgaactt aagtgacgaa tcggcaaagt ccgagaagcg
     1021 gaccaccgtc tcgtgatcgg ggtcgttcat gacctcaggt agggactggg cggcttcctt
     1081 catcaagcgg agaacgaggt ccacatcgct gccgtacgcc acatcgacgc ccacggcgat
     1141 cttcagccgg cggtccggtt gcaccatgtt cacgatcttc ttgttggcga tgtcgttgtt
     1201 cggaacgatc accatctcat tggtgaaggt gttgtacagc tccgtcgccc gcatgcctat
     1261 gtgccgcact tcgcatatgt cgccgttatc cagacggaga aggtcgccca gcttgaaggg
     1321 gcggtcgaac atcatctgca tcccggcaaa gaagttggcc agggtggcct gggcggcgta
     1381 acctatgacg atacccatga aacccagtcc ggccaatatc accgtcagat tatatccgaa
     1441 cagaccgagg atcaccgcca gggcgattat gggtatgact atcattccca gtttttcaaa
     1501 tatcgggacc agaacgtcgt ccacctcgga gtcggtcttg gcggccagct tgtggccgta
     1561 gaacacgatg accccggcgt atatcttgta tgatagccag gctatggcca gtatgaacgc
     1621 cacgctgtag gcgagctcca ggtcggcgat caggacccgg ttaaggttca agatctccaa
     1681 tgaacgcacc gccccgtaga gcaccatgag caacaggacc gggccgcgaa tgatccttag
     1741 gatgatatcg tccagctcgg tggcggtctt ggaggtcagg cggtgcaata acggatcggc
     1801 cactagtatt acgaacagcg cgatcacggc ccatatgccc acgcttacca cgaaggcacc
     1861 ggcgttcccg tccaatggcc agggaaggtt gttatcccag atccccagga tcttgttgtc
     1921 accggctccc gcgccgaaga ccgggacgac atcgaggcgc accgtgtcgc tgatggagaa
     1981 ggtgttgccc agctcgttca tctgggtgat gttgaagcgc acttcgaaga ccgtggcaga
     2041 ctcgggcatc tcccgtaccg tggtcacggt catgatgatg gattccgatt ccccgggata
     2101 cagcgtgaga tagctctgat cgaagtccac cgagaactca gcgttgctgg tctgatcgga
     2161 ggagggagtt atgacgtagg gaacggtgtc attgttgtag agtatccact caaaactggc
     2221 gggagtgcca gcgacggtgg tcagttcgtc ctgcccgacc atgaaggcgt tgacctggcc
     2281 cgcggacgcg gtcggagcga aggctgccgt gaagaccagc agcccgagca acatgagccc
     2341 ggcgaggttg agaaccgtcc gtgacctcat cgtactttcc ctggcgggcg ttaaacttac
     2401 cgcatattta ggatttctcg cccgcatcgg tggcaaacca ttaatcgtcg ttcgtccctt
     2461 gaccgagcat ggaagagctg acctgggccc ggatagcact ggccctggcc atcatggtcg
     2521 ccgcctcggt gtccgattgg cgcagccgta cagcgtccga tgttcactgg tacatcctgg
     2581 gcatcggtgg ttccatcctg ttcggcctgc agctcttctt cgacggcgcc ccatggatat
     2641 tcctggtctg ccttgccctc atgaccctgg tgttcgccga cctcctgtgg gaccggccgg
     2701 ggatatttga ggatggggtg aacgttcctc cgttggttct ttacgttctt acgttcctgg
     2761 ccttcggtta cttgagcttg gagcatttcg gcgaggggcg ctattggacc atgctctcca
     2821 taccgctgct catagtgttc ttcttcgtca tgtatcagct ggatgtcata aagggcggag
     2881 cggacgccaa ggcgctcata gccctctccc tggtattccc gatctatcca gaactgtccg
     2941 gactgccgtt gctggaactt aacgacccag cagcgttgac catactcccg ttcccggtgc
     3001 tggtgctctt caacggagcc atactgacgt tgctggtgcc ggtcgggatg ttgctgatga
     3061 acctggtccg ccgggacctg cgattcccat cgatgctgtt cggcactagg atgaccattg
     3121 acgatgcgag gaagaagcac gtctggccca tggaacgagt cgccgatggg aaagttaaaa
     3181 cggtactgtt cccccgctcg gacgaggagg cggactggga tgcgttgcgc caggcgggag
     3241 tggaccggcc atgggtcacc cccaaggtac cgttcctgat accgctcacg ttagcggtgc
     3301 ccttctccct gctgatggga aatatccttc tgtacctgat gggcgcttga acggtactac
     3361 cagacgatat cggcggggcg tccgcatttc gagcacgccc ggtccttgat cccgacgatc
     3421 tcggcggaga accccgaacg gcggacgagc agcgaggagc atttcggaca ataggtgttc
     3481 tctccctttt ccgtggcgat attgccgacg tacacgtaat ccagcccgtg agccttgcct
     3541 tccttcaatg ccaggtccat ggtggaacgc ggcgtcggag gaacgtcctc catcttgtaa
     3601 tcgggatgga agcgggagaa gtgaactggc gtctgcgttc ccatgctatc acgtacccat
     3661 tggcagaagt cggcgatctc ttgccgccgg tcgttctttc cgggaatgat tagataggtc
     3721 agctccacgt ggatcccgat ctccctggcc acctcgcacg ctctgagcac cggcgccagg
     3781 ctgcccttgc acacctcgcc gtagaagttc tccgtgaatc ctttcacgtc gatgttcatg
     3841 gcgtctatga cgcctctcag agaacggagc ggctcctcct ggatgaatcc gttggtgacg
     3901 gagacggtga ataggcctcg ttccttgcac agacggcttg attcgaacat gtactcgtac
     3961 cagatggtcg gctcgttgta ggtccaggcc acgccgttgg aaccggcttt atggcacatc
     4021 tccggaactt gctccggcgg aacgtaacgt gacatgccgt tctcgagacc gacctgggcg
     4081 atggtgaagt tctggcagtg ctggcagcgc aggttgcagc tcagaccgcc gaacgacagc
     4141 accggctcgc cagggcggaa gtggaacagc ggcttcttct ccagggggtc cagatgcacc
     4201 gaggacacca tgccgtagct gatggccttc agagtaccgt caacgttctg gcgcacccga
     4261 catattccgg tcttgccttc cttgatcaga caggaatgcg ggcatagctg gcaacgcaag
     4321 gtgttccctt ctcgctccca gaacagggca tccttcagct cagtgccgga agtgctcata
     4381 tccctt
//
LOCUS       DAOPZI010000055         4013 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_29432_length_4013_cov_6.061900, whole genome shotgun sequence.
ACCESSION   DAOPZI010000055 DAOPZI010000000
VERSION     DAOPZI010000055.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 4013)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 4013)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4013
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_29432_length_4013_cov_6.061900"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1018
                     /locus_tag="PKM11_07815"
     CDS             <1..1018
                     /locus_tag="PKM11_07815"
                     /inference="COORDINATES: protein motif:HMM:NF012382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX48447.1"
                     /translation="KELAKRAVETHGVGSGSVRPIAGTMDLHLELEERLARFKGRPAS
                     LVYQTGFAANSGLIPQLAGKGDLIISDELNHGSIIDGVRLTSAERAIYRHCDTDDLAL
                     KLEEAESKDTTYRRILIITDGVFSMDGDMAPLDKIGKLAKDHGAMLYVDDAHGEGVLG
                     EGGRGIVSHFGLDHDTVQVEMGTFSKAFGVVGGHVSGSTDLKNFALNKSRTWLLSGSH
                     PPAVVAACIGAIDVLENEPQHVRNLWKRTDRFRKAMRDLGFDTGRSVTPIIPVMVGDS
                     AKAKRLSERLYQEGIFALPIIFPMVARDKARIRTIMNAALSDEDIDHAVSKFERIGRE
                     LGII"
     gene            1048..1719
                     /locus_tag="PKM11_07820"
     CDS             1048..1719
                     /locus_tag="PKM11_07820"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48448.1"
                     /translation="MFEHISPTQAAVEFFYGLLMAMTLSNTLRLALIGSSIGDVVFIV
                     SVAIFGCNLAWGIADGAVSVLTSHFQNLYYYRKVKQIKEGADQEAARELAAEVLSEAL
                     TEIQEDILDDEARKRMADVAIHAIKRKEIVKPTLGRSQWITAGWCVLLNVAAALPFIA
                     IYQMAFLLDLNLVTLLANITGAALLFFLGRFLDRRLGDGTGRTGLVMVGLGMLMLAII
                     VALGG"
     gene            1769..2311
                     /locus_tag="PKM11_07825"
     CDS             1769..2311
                     /locus_tag="PKM11_07825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48449.1"
                     /translation="MFAYNLLVTFHGNQRGHSEQEARERLTELGAYVERLETCEVEGV
                     FLIQAGGDAKVLVSQLKRLCQEDPVGFQYTHHWVPIERWMPSDKEEIRRNALELGKSI
                     GTNETWMMHLHKRHMPEHYDDLIAYLTEPLNRGTVDLFDPDRILAVEILGKSTGMSLL
                     TRHELLDVNQVRNESEQGKV"
     gene            2511..2753
                     /locus_tag="PKM11_07830"
     CDS             2511..2753
                     /locus_tag="PKM11_07830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48450.1"
                     /translation="MEKILPLLMVSPQVEKLFTALVKAGATAEDKAVSAEKATSLSKL
                     PKAQCMNAIQELKKAGALKDKKNNNSVYYYLVKTSL"
     gene            2887..>4013
                     /locus_tag="PKM11_07835"
     CDS             2887..>4013
                     /locus_tag="PKM11_07835"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HNX48451.1"
                     /translation="MDAVETAARNAKEASYRLQSLTQAVRNEALQEIAAALQDHADEI
                     VKANQADVREAEKAGLSKVLVKRLRYDQTKIKESVDSLRSLIRQEDPIGKVVSRTELD
                     ADLVLERVTCPIGVIGVIFEARPEALVQISSLCLKSGNAVILKGGSEAHRTNEALANV
                     IVKAVTDLDERFASAVQLLSTREEINHLLAMDQFVDLIIPRGSNQLVRFIKEHTKIPV
                     LGHADGICHTYVDGSADLDMALSVCFDAKVQYPAVCNAMETLLVHENVALTFIPAMAE
                     RFHQAGVELRGDDGACALAEMKEASEEDWSAEYNDLVLSVKIVSTLEEAVQHINRYGS
                     HHSDAIIASDERAAKRFMDEVDSASVMWNCSTRFADGFRYGL"
BASE COUNT          881 a         1124 c         1257 g          751 t
ORIGIN      
        1 caaggaactg gccaagagag cggtcgagac gcacggggtc ggttccggtt ccgtgagacc
       61 tatcgccggt accatggacc tgcacctgga gctggaggag cgtctggcaa ggttcaaagg
      121 ccgccccgcc tcgctcgtct accaaacggg tttcgccgcc aactccggat tgatccctca
      181 gctggccggg aagggggacc tcataatctc ggatgaactt aaccatggca gcataatcga
      241 cggcgtccgc ctcacttcgg cggaaagggc catctacagg cactgtgaca cggacgacct
      301 ggcattgaag ctggaggagg cggagagcaa ggacacgact taccgccgaa tcctgatcat
      361 aacggacggg gtgttctcca tggacgggga catggccccc ctggacaaga taggaaaatt
      421 agcgaaggac catggcgcga tgctctacgt ggacgatgcg cacggcgagg gggtgctggg
      481 cgagggcgga cgagggatag tctcgcactt cggactggac cacgataccg tgcaggtgga
      541 gatgggcacc ttctccaagg ccttcggcgt cgtcggcgga cacgtctccg gttccacgga
      601 tctcaagaac ttcgctctga acaaatcgcg cacttggctg ctcagcggtt cccaccctcc
      661 ggcggttgtc gcggcgtgca taggagcgat agatgtcctg gagaacgagc cgcagcacgt
      721 gcggaacctc tggaagagaa cggaccgctt ccgcaaggcc atgcgagacc tgggcttcga
      781 tactggacgt tccgtaacgc ccatcatccc ggtgatggtc ggcgacagcg cgaaagcgaa
      841 acgactgagc gagagactgt accaggaagg gatattcgcc ctgccaataa tattccccat
      901 ggtggcccgg gacaaggccc gcatacgtac gattatgaac gccgccctga gcgatgagga
      961 cattgatcat gccgtcagca agttcgaacg gatcggccga gagctgggga taatctgagc
     1021 tcggacgaga gcctattgga ccggctgatg ttcgagcaca tcagccccac ccaggcggcg
     1081 gtggagttct tctacgggct gctgatggcc atgaccctca gcaacaccct gcgcctggcg
     1141 ctgatcggca gctccatcgg cgacgtggtg ttcatcgtct ccgtggccat attcggctgc
     1201 aacctggcct ggggcatcgc cgacggggcg gtcagcgtgc tgacctcgca cttccagaac
     1261 ctctattact atcgcaaggt caagcagatc aaggaggggg cggaccaaga ggcggccagg
     1321 gagctggcgg ctgaggtcct ttcggaggcg ctgaccgaga tccaggagga tatcctggac
     1381 gatgaggcgc gcaagcgcat ggccgatgtg gcgatccacg caataaaacg caaggagatc
     1441 gtcaagccca ccctgggacg ttcgcagtgg atcacagccg ggtggtgcgt tctcctgaac
     1501 gtcgcggccg cccttccctt catcgcgata taccagatgg cgtttttgct ggacctgaac
     1561 ctggtcactc tcctcgccaa tatcaccggg gcagcgctcc tcttcttcct agggcgtttc
     1621 ctggaccgcc ggttaggcga cggcaccgga cggacgggat tggtcatggt cggcctgggc
     1681 atgctgatgc tggcgataat cgtggccttg ggcggctgag gggaagttat ttgtgcgcgc
     1741 acgctaaagt gataacgagg tgcgcagcat gttcgcctat aacctcctag tgacctttca
     1801 cggcaaccag agaggccact ccgaacagga agcgcgggag cgattgacgg aactgggggc
     1861 atacgtggag cggctggaga cctgcgaggt ggaaggggtg ttcctgatac aggcgggagg
     1921 ggacgccaag gtcctggtct cccagctcaa gcgcctgtgc caggaggacc cggtggggtt
     1981 ccagtacacc catcactggg tgcccatcga gagatggatg ccctcggaca aggaggagat
     2041 caggagaaac gccttggagc taggcaagag catcggaacg aacgaaacgt ggatgatgca
     2101 cctgcacaag cgccatatgc cggagcatta cgacgatctg atagcctacc tgacggaacc
     2161 tttgaaccgc ggaacggtgg acctcttcga tccggacagg attctggccg tggagatact
     2221 gggaaagagc accggcatgt cgttgctgac caggcacgag ctgctggacg ttaaccaggt
     2281 ccgcaacgag tccgagcaag gcaaggtgtg aaggaccggc gtccccgagc ttcagagtag
     2341 cgggagcttt gttcccatgg atgtttagcg catttgagct tgcttccttg gttccgcgag
     2401 acgtttgctc acattgatta tattacttag acaaaatatt ggcggacgcc gtccattaaa
     2461 taattttact gtgttatata aaatgtggga gggaccgcaa tctttaataa atggaaaaaa
     2521 ttctcccgct tctcatggta tcccctcaag ttgaaaagct gttcaccgcg ttggtaaagg
     2581 ccggagcgac cgccgaggac aaggccgtga gcgccgagaa ggccacctcc ctgtccaagc
     2641 tgcccaaggc gcagtgcatg aacgccatcc aggaactgaa gaaggctggc gccctcaagg
     2701 acaagaagaa caacaactcc gtctattatt atctggtaaa aacttcgctg tgaacatacc
     2761 cggggatgcc tggcatccct cgggatgctc tagagaaact cattacctca acatcctgtt
     2821 ctagacctgt accacgtgag cttgtcgaaa ggttcatcaa atccacccgc catgccatgc
     2881 tccgtcatgg acgctgtgga gactgccgca aggaacgcca aggaggcctc gtaccgtttg
     2941 cagagcctga cccaggcggt caggaacgag gccctgcagg agatcgccgc cgccttgcag
     3001 gaccatgcgg acgagatcgt gaaggccaat caggccgatg tcagggaggc ggagaaggcc
     3061 ggcctgtcca aggtgctagt gaagcgcttg cgttacgatc agaccaagat caaggagtcc
     3121 gtggattccc tgcgttcgct gatcaggcag gaggatccta taggcaaggt cgtatcgcgc
     3181 acggagctcg atgcggacct ggtcctggaa agggtgacct gcccgatagg cgtcataggc
     3241 gtgatattcg aggcgcgacc ggaagcattg gtgcagatat cgtcgctatg cctgaagtcc
     3301 ggcaacgccg tgattctcaa gggcggttcg gaggcccatc gcacgaacga ggccctggcc
     3361 aacgtcatcg tcaaagcggt caccgacctg gacgagaggt tcgcttcggc cgttcaattg
     3421 ctatcgacac gagaggagat caatcacctt ctggctatgg accagttcgt cgatctgatc
     3481 attccgcgag gttccaatca attggtccgt ttcatcaagg agcacaccaa gatcccggtg
     3541 ctcggtcatg ctgacggaat atgccacacc tatgtggacg ggtcggccga tctggacatg
     3601 gctcttagcg tctgcttcga cgccaaggtg caatatcccg cggtgtgcaa cgccatggag
     3661 accctgctgg tgcacgagaa cgtggcgctc accttcattc cggccatggc cgaacggttc
     3721 caccaggcgg gcgtagagct tcgcggtgac gacggagcgt gcgcgctggc ggagatgaag
     3781 gaagccagtg aggaggactg gagcgccgag tacaacgacc tggtgctctc ggttaagatc
     3841 gtatccaccc tggaggaggc ggtgcagcac atcaacaggt acggatcgca tcacagcgac
     3901 gccatcatcg cctcggacga gagggcggct aagcgcttca tggacgaggt cgactcggcg
     3961 tccgtcatgt ggaactgctc cacccgcttc gcggacggct tccgttacgg gct
//
LOCUS       DAOPZI010000056         3985 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_29761_length_3985_cov_5.884987, whole genome shotgun sequence.
ACCESSION   DAOPZI010000056 DAOPZI010000000
VERSION     DAOPZI010000056.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 3985)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3985)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3985
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_29761_length_3985_cov_5.884987"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(55..>1344)
                     /locus_tag="PKM11_07840"
     CDS             complement(55..>1344)
                     /locus_tag="PKM11_07840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48452.1"
                     /translation="EMLGEIACILKIKDTVPGDYRHGRVLMLEAAEQLDSNALWALRT
                     LRKARRSFEEESEIAKRYNTFTAKWAKMDPYHFGSEEKRLERDLYQLLRDGEFEQCAD
                     VLLQLERLVDMDVAENIEIGLLLEVVNPDIQLGKGTTLSILVHNHSAFPIKLDSLKGS
                     SPQATVHVLDFYKGVMKKDEDHKCQINVIPKVEGDIVVQVEAVIHNDSRPLRISKGFS
                     LKVNVPEQVVQYVDARTPTEVQYVRPKEGPRPVTKAPSSFDPLELTASGTVDQWFTCV
                     TVFARNRSPVDLSGLAAKDPNFVKSDGYANLFRALLAMRYDPNVDWASWFQEAGFMGE
                     DYTKRCSKLLWQIGSSKDRSVELEMDGSVGSSNIENLIGAMQIASGEVRREERSRKAW
                     TVEGTMDGAAFSLKIERTVRKDEQGKAVASTFRIVSG"
     assembly_gap    1345..1444
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(1464..1586)
                     /locus_tag="PKM11_07845"
     CDS             complement(1464..1586)
                     /locus_tag="PKM11_07845"
                     /inference="COORDINATES: protein motif:HMM:TIGR04272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48453.1"
                     /translation="MHDVVCSDCGAATQVPFKPTEGRPVYCRDCFQKHKPKDRF"
     gene            1915..3375
                     /locus_tag="PKM11_07850"
     CDS             1915..3375
                     /locus_tag="PKM11_07850"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HNX48454.1"
                     /translation="MRELNIVTNFTDLQISKDIIKAMNDMGWEEPTPVQVEAIPVGLK
                     GGDMYAQAQTGTGKTGAYGAIILERVKPRMPTPSALILVPTRELANQVAEELTKLSKY
                     TGHDCLPIYGGVGIEPQISKLKRGIDIVIATPGRAKDLINRNALDLSHVTVAVLDEAD
                     RMLDMGFIRDINFILAKVPKKRQALLFSATMSSEIREMAMRQMVNPVEVLVSKDEPVL
                     DLTKQYYVIVDKDDKRDALYTVLDMYEPKAIVFCHTKHKADQVTKKLQRHNYSAEAIH
                     GDVAQNKRERVLKSFKDGSIRVLVATDVAARGLDIDSVDYVINFDAPSDPDTYVHRIG
                     RTGRAGKEGAAISFFLPEERREVRGLERRTGKTIERLDIDIVHKDEPEVKKLDEVRLA
                     VQASSNQPVAAKRTRSHGNVASIEINLGGADKVGKGEIVRLVKNDTGLGARDIGKITM
                     GDRYTFVEVFKKDAEKVIMSLNNQFYGNKPVKARMV"
     gene            3484..3957
                     /locus_tag="PKM11_07855"
     CDS             3484..3957
                     /locus_tag="PKM11_07855"
                     /inference="COORDINATES: protein motif:HMM:NF019819.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HNX48455.1"
                     /translation="MSELQTVDYVDVERYMGTWYEIAKFPQTFENGLVGITATYSLLP
                     NGKVRVLNSGYVGDFNGKLKTAKGKAWVVDKKTNAKLRVSFFWPFAGDYWIIELGKDY
                     EYAVIGENSRKYLWILSRTPKMDERVYEGIVERLKGNGFDISMIELNPQQGGSLG"
BASE COUNT          870 a         1086 c         1112 g          817 t
ORIGIN      
        1 ggctcggacg agaacagctc tcagaaggcc aaggagctca tcgaccggat gtactcatcc
       61 tgagacgatc cggaacgtgg aggccaccgc cttcccctgt tcgtcttttc tgacggtacg
      121 ctcgatcttc agcgagaagg ccgccccgtc catggtcccc tcgacggtcc acgcttttct
      181 ggaacgctct tcacgccgga cctctccgga ggcgatctgc atggccccga taaggttctc
      241 gatgttcgag ctgcccacgc tgccgtccat ctccagctcg accgagcgat ccttggacga
      301 accgatctgc cataggagct tggagcagcg cttggtgtaa tcctcgccca tgaatcccgc
      361 ctcctggaac caggaggccc aatcgacgtt ggggtcgtag cgcatcgcca gcagcgcccg
      421 gaagagattc gcataaccgt cagatttaac gaaattgggg tccttggccg ccaaaccgga
      481 aaggtcgacc gggctgcggt tcctggcgaa cacggtgacg caggtgaacc actggtcaac
      541 ggtcccggaa gcagtaagct ccagggggtc gaaggacgag ggagccttcg ttaccggtct
      601 cggtccttcc ttcggtctca cgtactggac ctcggtcggg gttctggcgt ccacgtactg
      661 cacgacctgc tccggcacgt tgaccttcaa ggagaagccc ttgctgatgc gcaagggacg
      721 ggaatcattg tggatgaccg cctctacctg gaccacgatg tcgccctcca cctttggtat
      781 gacgtttatc tggcacttat ggtcctcgtc cttcttcatc acgcccttgt agaaatcaag
      841 gacatggacg gtggcctgcg gcgaactgcc tttcaaggaa tccagcttta tggggaaggc
      901 gctgtggttg tggaccagga tgctcagcgt agttcccttg cctagctgga tgtccgggtt
      961 caccacctcc aggagaaggc cgatctcgat gttctccgcc acgtccatat cgacgagtcg
     1021 ctctaactgc aggagcacgt cggcgcactg ctcgaactca ccatcccgga gcaattggta
     1081 aaggtccctc tccaatcttt tctcctcgga accgaagtgg taggggtcca tcttggccca
     1141 tttggcggta aaggtgttgt agcgcttggc tatctcgctc tcctcctcga aggagcggcg
     1201 ggccttgcgc aacgtccgta atgcccacag ggcattggag tccaattgct cggccgcctc
     1261 cagcatgagc acccggccgt gccggtaatc cccgggaacg gtgtccttga tcttgaggat
     1321 gcaggctatc tccccgagca tctcnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nnnnatgttg aagcttaacc tatttagaac cggtccttgg gcttgtgctt ctggaagcag
     1501 tccctgcaat agacaggcct gccctcagtg ggcttgaagg ggacttgggt cgctgcgccg
     1561 caatcggagc aaacaacgtc gtgcatttcg cggggtccat cgttcctagg gcggttgtag
     1621 ccgccagaat tacctctgtt tccgtacatt actaaactac ctactgtttg ttatatctcg
     1681 tccccttgcg gacacgggat gaatgagcca tatttcccct agtatttaag ctaatttatt
     1741 ctaacagtat ttaatttatt tatctatatg ttataattaa ttggtccgga cgttatagac
     1801 gtaaaccgtc tggcctccag aacccctatt tgtaggcaca tttatatatg cgaagagcaa
     1861 ccaccgattg aaatcaaaat cgtctgttat ctatacagtt cgttttttat tttcatgaga
     1921 gagctgaaca tcgtgaccaa tttcacagat ttacagatat ccaaggatat catcaaggcc
     1981 atgaacgaca tgggatggga agagcccacg cccgtacagg tagaggctat ccccgtcggc
     2041 ctgaagggcg gggacatgta cgctcaggcg caaacgggaa ccggaaagac cggggcctac
     2101 ggcgcgatca tacttgaacg ggtaaagccc aggatgccca ccccgtcggc gctgatactg
     2161 gtccccacca gggagctggc caaccaggtc gccgaggagc tgaccaagct atccaagtac
     2221 accggtcacg actgcctgcc gatatacggc ggcgtcggaa tcgagcctca gatatccaag
     2281 ctgaaacgcg gcatcgatat cgtcatcgct acaccgggcc gggcgaagga cctgatcaac
     2341 cggaacgctc ttgacctgtc gcacgtcacc gtggccgtgc tcgacgaggc cgaccgcatg
     2401 ctggacatgg gcttcatccg cgacatcaac ttcattctgg ccaaggtgcc gaagaagagg
     2461 caggcattgc tgttctcggc caccatgtcc tcggagataa gggagatggc catgcggcag
     2521 atggtgaacc ccgtggaggt tctggtatcc aaggacgaac cggtcctcga tctcaccaag
     2581 cagtactacg tcatagtgga caaggacgac aagcgcgacg cgctttacac cgtcctggac
     2641 atgtacgagc cgaaggccat cgtcttctgc cacaccaagc acaaggccga tcaggtgacc
     2701 aagaagctgc agaggcacaa ctattcggcc gaagcgatac acggcgacgt ggcccagaac
     2761 aagagggaga gggttctgaa gtccttcaag gacgggtcca tccgtgtcct ggtggcaacg
     2821 gacgtcgccg cccgcggtct ggacatcgat tccgttgatt acgtcatcaa cttcgacgcg
     2881 ccgagcgacc cggacaccta cgttcaccgc atcggtcgga ccggccgcgc gggaaaggag
     2941 ggagcggcga tatcgttctt cctacccgag gagcgccgag aggtcagggg tctggagcgc
     3001 cgcaccggca agacgatcga acggttggac atcgacatcg tgcacaagga cgagccggaa
     3061 gtcaagaagc tcgacgaggt ccggttagcc gttcaggcgt cttccaacca accggtcgct
     3121 gccaagcgca cccggtcgca cggtaacgtc gcctccatcg agatcaacct cggcggggcg
     3181 gacaaggtcg gcaagggcga gatcgtcagg ctggtcaaga acgatactgg gctgggggca
     3241 agggacatcg ggaagatcac catgggcgac cgctacacct tcgtcgaggt gttcaagaag
     3301 gacgccgaga aggtcatcat gagcctgaac aaccagttct acgggaacaa gcccgtgaag
     3361 gcccggatgg tctaggccgt ccgacctccg tccaatcctt ttatttcttt tttctttcag
     3421 tgatgggtca aaagaccctc actaccaatt taatcttgaa cataggtatc gaggatcgtt
     3481 attatgtccg agctacagac cgttgattac gttgacgtcg agagatacat gggaacctgg
     3541 tacgagatag caaagttccc gcagacattc gagaacggtc tggtcgggat aaccgccacg
     3601 tactctctgc ttcccaacgg aaaggtcagg gtgttgaaca gcgggtacgt cggtgacttc
     3661 aacggtaagt tgaagacggc caagggtaag gcgtgggtgg tcgacaagaa gaccaacgcc
     3721 aagctcaggg tgagcttctt ctggccgttc gctggggatt actggatcat cgagctgggg
     3781 aaggattacg agtacgcggt gatcggcgag aattcacgga agtacctttg gatactgtcg
     3841 aggaccccga agatggatga acgggtgtac gaaggtatcg tggaacgatt gaaggggaat
     3901 ggtttcgaca tatccatgat tgaattgaac ccgcaacagg gcgggtcatt gggttagacg
     3961 gactctagca atgacgatct tcaat
//
LOCUS       DAOPZI010000057         3563 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_35102_length_3563_cov_9.993729, whole genome shotgun sequence.
ACCESSION   DAOPZI010000057 DAOPZI010000000
VERSION     DAOPZI010000057.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 3563)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3563)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3563
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_35102_length_3563_cov_9.993729"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(63..767)
                     /locus_tag="PKM11_07860"
     CDS             complement(63..767)
                     /locus_tag="PKM11_07860"
                     /inference="COORDINATES: protein motif:HMM:NF014826.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HNX48456.1"
                     /translation="MPRPRINLHTHTLYSDGDFTVMEVVSSAFKAGLTHVAITDHFET
                     CKIINPLKRMDFERYLRDLQAARMMYEGRINVLAGVEIDTNPQRCDLYELPFDLLNEL
                     DLVLFEYVEDPLQGGIPLNELRSLTKDLKVPFGFCHWDMDRIYHDRDPSWLADRLAEV
                     GAFVEVPTSQHYARDGRFLFEHSERFYRAFKGKVKVSIGTDMHHSLGEVGNIGRGLDF
                     LRSNGLCGQLLFNEEK"
     gene            complement(839..>1150)
                     /locus_tag="PKM11_07865"
     CDS             complement(839..>1150)
                     /locus_tag="PKM11_07865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hexulose-6-phosphate
                     synthase/ribonuclease regulator"
                     /protein_id="HNX48457.1"
                     /translation="RDIDGIIDLRFPCFSRHVSPHAGEPKGFGGIGLEIVCGGQMVRT
                     GDWIVGDESGVIVIPQEHAVELANRSVDVWEREERIREEIKRGGTLSKVQELEKWEQV
                     K"
     assembly_gap    1151..1250
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<1251..1957)
                     /locus_tag="PKM11_07870"
     CDS             complement(<1251..1957)
                     /locus_tag="PKM11_07870"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine 5'-phosphate decarboxylase"
                     /protein_id="HNX48458.1"
                     /translation="MQPVLQVALDLMHLKRAVEIARESLEGGADWIEAGTPLIKSEGA
                     ECLRSLKKEFPGRTLVADMKTMDVGAFEVEIAAKAGADIVTVLGLSDDGTISESVLAA
                     RKYGAAVMVDMINVPDKVKRAKRAEELGASYVCLHVGIDEQMKGEGSPLEIVSKVSKA
                     ISIPLAVAGGITSETAPKMIEHGASIIIVGGGIIKTGDVRSAARAVKEGMRTGKGLPN
                     ALARKYGQEELFEAFAKV"
     gene            2033..2743
                     /locus_tag="PKM11_07875"
     CDS             2033..2743
                     /locus_tag="PKM11_07875"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HNX48459.1"
                     /translation="MAASPGAKFCTGMECIDRIVGGGFPAGGMITVSGPCGSGKTLFG
                     IEYLMRGALAGQKGVYISTAHRPEKMMAFVPKLDYADAKLWESGKISLKHIDDMGSGE
                     RDDGKITKGEAEAMIEDIATAIKETKASRLVLDAMNPLMLEMEGWVARRFLISLSNLL
                     FESKCTGIIISEGESMDTLEHTISDGIVKLGTAVRRGDNYRVLEVVKMSGAGHSRAKY
                     VMDMTSEGMLITPMLRGV"
     gene            2745..3314
                     /locus_tag="PKM11_07880"
     CDS             2745..3314
                     /locus_tag="PKM11_07880"
                     /inference="COORDINATES: protein motif:HMM:NF018455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase domain-containing protein"
                     /protein_id="HNX48460.1"
                     /translation="MEEVAPQVLSRLNELGPAVSIDFNIGVEAYFDTLTTLVDRFCNK
                     KGLSCIYISVTMPASTIRSALQSLEIDAEKLRFVDCISFATMECSANDDDRTVFVESP
                     TMLEYIVLKMEYLFRKGKDEQFMVILDSVNSLAAHNEVRMLYEFMQVLMASVKSRGAY
                     PVLLSMEEQMKPDVLEMLQLVCDQIVTLK"
BASE COUNT          717 a         1033 c         1006 g          707 t
ORIGIN      
        1 atcaagaggc tcaagcagca ggccagcgag atgggccgtt tctgaaaccc cttatcaaat
       61 tttcatttct cttcgttgaa cagcagctgc ccgcacaatc cgttcgagcg caggaagtcc
      121 agtccgcggc cgatgttgcc aacctcgcct agcgagtggt gcatgtccgt gcctatggac
      181 acctttacct ttcctttgaa cgcccggtag aacctttccg aatgctcgaa aaggaaacgg
      241 ccgtcccggg cgtaatgctg cgacgtggga acctccacga acgccccgac ctccgcaagc
      301 ctatcggcga gccaggatgg atcgcggtca tggtagatgc ggtccatgtc ccagtggcag
      361 aacccgaacg gcaccttcag gtccttggtg agcgagcgca gctcgttcaa cggtatccca
      421 ccctgcagcg ggtcctccac gtattcgaat aagaccaggt ccagctcgtt caaaaggtcg
      481 aacggcagtt cgtaaagatc gcagcgctgc gggttggtat ctatttccac cccggccagg
      541 acattgatgc ggccttcgta catcatcctg gccgcctgga ggtccctcag gtagcgttcg
      601 aaatccatgc gcttcagggg attgatgatc ttgcacgttt cgaagtggtc ggtgatggcc
      661 acgtgcgtca gcccggcctt gaacgccgag ctcacgacct ccatgaccgt gaagtccccg
      721 tccgagtaga gggtatgggt gtggaggtta atccggggcc gcggcatcac cgcgatatgt
      781 cccgcagggg tgatataaac gctttcatcg aacctttaac ggtccgacga gcatccgatc
      841 acttcacctg ctcccacttc tccagctcct ggaccttgga cagggtgccg ccgcgcttga
      901 tctcctcccg gatgcgctcc tcgcgttccc agacgtccac ggaacggttg gccagttcta
      961 cggcatgttc ctgcggaatg acgatgaccc cgctctcgtc gccgacgatc caatccccgg
     1021 tccgcaccat ctgtcccccg cagactatct ccaggccgat cccgccgaag cctttcggct
     1081 cgccggcatg tggcgacacg tggcggctga agcacgggaa ccgcaggtcg atgatgccat
     1141 cgatgtcccg nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn accttggcga
     1261 aggcctcgaa gagctcctcc tgcccatact tcctggccag ggcgttcggg agccccttgc
     1321 cggtacgcat gccctccttc accgcacgag cggccgagcg cacgtccccg gtcttgatga
     1381 tgccgcctcc cacgatgatt atggacgcgc cgtgctcgat catctttggc gcagtttcgg
     1441 aggtgatgcc cccggccacg gccagaggga tgctgatggc cttggagacc ttggagacga
     1501 tctccaacgg cgacccctcg cccttcatct gctcgtcgat gcccacgtgc agacacacgt
     1561 aggaggcgcc cagctcttcc gcccgcttcg ctcgtttgac cttgtccggc acgttgatca
     1621 tatcaaccat caccgccgcc ccgtacttgc gcgcggcgag cactgattcg gatatcgtgc
     1681 cgtcatcgga aagcccgagg acggtgacga tgtccgctcc ggccttggcg gcgatctcca
     1741 cttcgaaggc cccgacgtcc atggtcttca tgtccgccac gagcgtccgg ccggggaact
     1801 ccttcttgag cgaacgcagg cattccgcgc cctcgctctt gatcagcggc gtccccgcct
     1861 ctatccagtc cgccccgcct tccagggatt ccctggctat ctcgacggcg cgcttgaggt
     1921 gcatgaggtc caaagccacc tgcaaaaccg gttgcatgaa cggacaatct ccgccagact
     1981 actaatcttt tccttcaaaa aataatatat ccgcagatac gcatcatcac gcatggccgc
     2041 atccccaggc gcgaagttct gcaccggtat ggagtgcatc gaccgcatag tgggcggggg
     2101 attccccgcc ggagggatga tcaccgtcag cggtccctgc ggttcaggca agaccttgtt
     2161 cgggatcgag taccttatgc gcggcgcctt ggccggtcag aagggtgttt acatatccac
     2221 ggcccaccgc ccggagaaga tgatggcctt cgttcccaag ttggactatg ctgacgccaa
     2281 gctgtgggag agcggcaaga tatcgctcaa gcacatcgac gacatggggt cgggggagag
     2341 ggacgacggc aagataacca agggcgaggc ggaagcgatg atcgaggaca tcgcgacggc
     2401 cataaaggaa acgaaggcca gccggttggt tctggacgca atgaacccgc tcatgctgga
     2461 gatggagggc tgggtggccc gccggttcct catatcgctc tcgaacctgc tgttcgagag
     2521 caagtgcacc gggatcataa tctccgaggg ggaatcgatg gacaccctgg agcacaccat
     2581 ctctgatggt atagtgaagt tgggcacggc ggtgaggcgc ggtgacaact accgggtgct
     2641 agaagtggtg aagatgtccg gcgccgggca ctcccgggcc aagtacgtca tggacatgac
     2701 ctcggaagga atgctcataa ccccgatgct caggggggtc tgagatggag gaagtggcgc
     2761 cgcaggtgct tagcaggctg aacgaactgg gtccggccgt gtccatcgac ttcaacatcg
     2821 gcgtggaggc gtacttcgac acgctgacca cgctggtcga ccgcttctgc aacaagaagg
     2881 ggctgtcctg catctacatc tccgtcacca tgcccgcgtc gaccatacga tcggcgctgc
     2941 aatcattgga gatagacgcg gagaagctgc gcttcgtgga ttgcatatcc ttcgccacca
     3001 tggaatgctc ggcgaacgat gacgaccgca cggtcttcgt ggagagcccg accatgctgg
     3061 agtacatagt gctcaagatg gagtacctgt tccgcaaggg gaaggacgag cagttcatgg
     3121 tcatactgga ctcggtgaac tcgctggccg cgcacaacga ggtgcgcatg ctatacgagt
     3181 tcatgcaggt gctcatggcc agcgtgaaga gccggggcgc ttatccggtg ctgttgagca
     3241 tggaggagca gatgaagccc gacgttctcg agatgctgca gctggtctgc gatcagatcg
     3301 tgacgctgaa atgagcttga tgagaaaggt tggtaaaaaa acgaagtttc gtattttttc
     3361 gtataaaacc cgtaatttat gacgatattt catcattttt atgattccag tgcagatagt
     3421 tatttatttt catacgagta aatatgtctc cggtagggca acctaccagg agactgaaca
     3481 catatgaaga aaatgtggaa gaagaataac aaggccgtat cgccagtcat cgccaccatc
     3541 ctgatggtcg cgatcaccgt ggt
//
LOCUS       DAOPZI010000058         3445 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_36898_length_3445_cov_11.631563, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000058 DAOPZI010000000
VERSION     DAOPZI010000058.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3445)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_36898_length_3445_cov_11.631563"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..528)
                     /gene="porA"
                     /locus_tag="PKM11_07885"
     CDS             complement(<1..528)
                     /gene="porA"
                     /locus_tag="PKM11_07885"
                     /inference="COORDINATES: protein motif:HMM:NF013974.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate ferredoxin oxidoreductase"
                     /protein_id="HNX48461.1"
                     /translation="MKVKVISADHAVAYAAMLARTEVVPSFPITPQTLIVEQLAEFIN
                     DGELDADFIPADSEHSVMSMAIGASAGGVRVFTATSSQGLALMHEMLYAVPQNRLPIV
                     MANVNRSLGAASGIWVEYNDSMAERDSGWLQIYVEDNQEALDATLMAFRLAEDRRVLL
                     PVMVCLDGFILSHTVE"
     gene            complement(525..1424)
                     /locus_tag="PKM11_07890"
     CDS             complement(525..1424)
                     /locus_tag="PKM11_07890"
                     /inference="COORDINATES: protein motif:HMM:TIGR02175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HNX48462.1"
                     /translation="MYEVRFHGRGGQGAVMAAQALAEAAVIEGRHAQAFPYFGAERRG
                     APVMAFARIDDRKISIKSQVYEPDLLVVLDESLLDIEPVARGLKRTGKAVINTRKLPT
                     EIDLGVEVECATVPATAIAMEFLKAPIVNTAILGAIVRMCDLVSMGSMQQAIENRFGE
                     KFGEVAARSNAGAAAAAYAQAAIGRCKGNRPLVQKREWLPGWRDIPIGTTLDERTVDE
                     VAVGPGASRQNLTGSWRVQTPRYDQEKCVRCLRCWFSCPEGCIKREEDDYVRWDLNYC
                     KGCGICSQVCPVAAIDMVKGGSR"
     gene            complement(1506..2429)
                     /locus_tag="PKM11_07895"
     CDS             complement(1506..2429)
                     /locus_tag="PKM11_07895"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: protein motif:HMM:NF005146.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transaminase"
                     /protein_id="HNX48463.1"
                     /translation="MKGKIWMDGSLVNFEDAKVHVLAHGFHYGTGVFEGIRVYHTAQG
                     RNIFRLRDHMVRFLNSAKVLQMKVPYSLDELCEACREVVREADPKGDYLRPLAFYGVH
                     PEFKIGLNPSKLGTNVSIMCTYMGVYMGKDQVEQGANIITSSWEKYSNHAAALNAKVS
                     GHYVNSVIAKLEAIQHGCDEALMLNPNGNVAEGTGENVFMVKNGKLFTPPVSAGILEG
                     ITRDCIMTIGRDLGLEVVEKDMTRSELYMADEVFMTGTAAEISPIRSIDNRLISEGKI
                     GPITKQLGVVFHKAAMGENPRYAGWSDLVKV"
     gene            complement(2439..2786)
                     /locus_tag="PKM11_07900"
     CDS             complement(2439..2786)
                     /locus_tag="PKM11_07900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015503980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HNX48464.1"
                     /translation="MVVNDEFGVMQRIMGEFTRRKINVDTIVVGKCEMPGKSRVVLTV
                     SDRKQAEWAVDSLQRLHDIIQVELVDESRQEAYALVGNSVGKARLIGSIEEVEKMLQA
                     TNPDRFIRAVNAL"
     gene            complement(2816..3040)
                     /locus_tag="PKM11_07905"
     CDS             complement(2816..3040)
                     /locus_tag="PKM11_07905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48465.1"
                     /translation="MRMLWFGLLVLGVVKGAGRRPKVIEGSDSHQLPWLSTPKYPAGQ
                     DNGRNDDGYYQPIKKNHSVRNYQLPIKGKK"
     gene            complement(3174..>3445)
                     /locus_tag="PKM11_07910"
     CDS             complement(3174..>3445)
                     /locus_tag="PKM11_07910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48466.1"
                     /translation="DVMKKLAMSGMTMVVVTHEMGFAREMADKVIFMDQGVIAEQGTP
                     EEIFVNPQNPRTKVFLRRILKEMGAMDPGIPTDFLPNGNGLQDNP"
BASE COUNT          604 a         1135 c          976 g          730 t
ORIGIN      
        1 ctccaccgtg tgcgatagaa tgaaaccgtc caggcacacc atgaccggga gcaacacccg
       61 gcggtcctcc gccagacgga aggccatgag cgtggcgtcc agggcttctt ggttatcttc
      121 gacgtagatc tgcagccatc ccgagtcgcg ctcggccatg gagtcgttgt actccaccca
      181 gatgccggag gccgcgccca acgaacggtt cacgttggcc atcacaatcg gcaagcggtt
      241 ctgcgggacg gcgtacagca tctcgtgcat cagggccagg ccctgcgagg acgtggccgt
      301 gaacacccgc acgccgccgg cgctggcccc tatggccatg ctcatgaccg agtgctcgct
      361 gtcggcggga atgaagtccg cgtccaattc tccatcgttt atgaactccg ccagttgttc
      421 cacgatgagc gtctgcgggg tgatggggaa tgacggaacg acctccgtcc gggccagcat
      481 cgccgcgtag gccacggcgt gatcggcgct gatgaccttc accttcatct cgatcccccc
      541 ttgaccatgt caatcgccgc gaccggacac acctgggagc agatgccgca ccccttgcag
      601 tagttgaggt cccagcgaac gtagtcgtcc tcctccctct tgatgcaccc ttcaggacag
      661 gagaaccagc agcgcaggca cctgacgcac ttctcctggt cgtaacgagg cgtctgcacc
      721 ctccagctgc cggtgaggtt ctgacgggac gcgccaggcc cgaccgccac ttcgtcgacg
      781 gtcctttcgt ccaaggtggt gccgatggga atatctctcc atccgggcag ccattccctc
      841 ttctgcacca gcgggcggtt acctttgcac ctgccgatcg ccgcctgggc gtaggccgcg
      901 gcggccgccc cggcgttgct ccgggcggcg acctccccga acttctcccc gaagcggttc
      961 tcgatggcct gctgcatgga ccccatgctg accaggtcgc acatcctgac gatcgcgccg
     1021 agtatcgcgg tgtttactat cggggccttg agaaattcca tggctatggc cgtcgccggc
     1081 acggtggcgc actccacctc cacccccagg tcgatctccg tgggaagctt cctggtgttg
     1141 attactgcct ttcccgtccg tttaagaccg cgggccaccg gctctatgtc cagaagcgat
     1201 tcgtccagca ctaccagcag gtccggctcg tacacctggg acttgatgct gatcttccgg
     1261 tcgtctatgc gggcgaaggc catcaccgga gcgccgcggc gctccgcgcc gaagtacggg
     1321 aacgcctgag cgtgcctgcc ctcgatgacc gccgcttccg ccaaagcctg ggcggccatt
     1381 accgcccctt gcccccctcg accgtggaac cggacctcgt acatagagca ccggtccatt
     1441 atctgagcgt ggcttattta acgctccgca tgtgagaaat aaaaaaaatg gttgatggaa
     1501 gacgtttaga ccttcaccag gtcggaccat ccagcgtagc gggggttctc gcccatggcc
     1561 gccttgtgga acaccacgcc cagttgtttg gtgatcggtc cgatcttgcc ctccgagatc
     1621 aaccgattgt cgatcgagcg gatcggggat atctcggccg cggtcccggt catgaacacc
     1681 tcgtcggcca tgtacagctc ggaacgggtc atgtccttct ccacgacctc gaggcccagg
     1741 tcccggccga tggtcatgat gcagtcgcgg gtgatgccct cgagtatccc ggcggacacc
     1801 ggcggggtga acagcttgcc gttcttgacc atgaagacgt tctccccggt gccctcggcc
     1861 acgttgccgt tggggttgag catgagcgcc tcgtcgcagc cgtgctggat cgcctccaat
     1921 ttggcgatca cggagttcac gtaatgcccg ctgaccttgg cgttgagggc ggcggcgtga
     1981 ttggagtact tctcccagga cgacgttatg atgttcgccc cctgctccac ctggtccttg
     2041 cccatgtaga cgcccatgta ggtgcacatg atgctgacgt tggtgcccag cttgctgggg
     2101 ttgagcccga tcttgaactc ggggtgcacg ccgtagaacg ccaacggtcg caggtaatcg
     2161 cccttggggt ccgcttctcg gaccacctca cggcaggcct cgcacagctc gtccaaagag
     2221 tacggcacct tcatctgcaa tacctttgcc gagttgagga agcggaccat gtggtcccgt
     2281 agccggaaga tgttccttcc ctgcgcggtg tgataaacgc gaattccctc gaagaccccg
     2341 gtcccgtaat ggaagccgtg cgccagcacg tgcaccttgg cgtcctcgaa attgaccaaa
     2401 ctaccgtcca tccatatctt gcccttcatc tcatcacctc agagggcgtt gaccgccctt
     2461 atgaaccggt ccgggttggt ggcctggagc atcttctcca cttcctcgat ggagccgatc
     2521 agccgggcct ttcccacgga attgccaacc agcgcgtagg cttcctggcg gctctcgtcc
     2581 accagctcga cctggattat gtcgtgcagt cgctgcaggc tgtccacggc ccactcggcc
     2641 tgcttgcggt cggagaccgt gaggaccacg cgggacttgc cgggcatctc gcatttcccg
     2701 acgacgatgg tgtccacgtt gattttgcgg cgggtgaact cgcccatgat cctctgcatg
     2761 accccgaact cgtcgttcac gaccatcgat aagacttcca tgtcgatccc tgtcctcact
     2821 tcttcccttt tatcggtaac tgatagttgc gcacgctatg gttcttcttt atgggttggt
     2881 aataaccatc gtcattgcgt ccattgtcct ggccggcggg atacttcggg gtggataacc
     2941 agggcagctg atgactgtcg ctgccctcga tcaccttggg gcgacgcccc gcgcctttca
     3001 ccacgcccag gaccagcagg ccgaaccata gcattctcat tgacagacca acctcacaat
     3061 gaacgggaaa gccaaaggct cccctttcag atacccaaga cgcgctggac cagaacaatg
     3121 tcggtgcgaa cgcacagcgc ttccatggtc cgtttgtatt tccgacagca tatttaaggg
     3181 ttgtcttgga gcccgttgcc gttcggcagg aagtcggtcg ggatgccagg gtccatggcc
     3241 cccatctctt tcaatatcct tctcaggaac accttggtgc gggggttctg cgggttcacg
     3301 aatatctcct cgggggtgcc ctgctcggcg atgaccccct ggtccatgaa tatgaccttg
     3361 tcggccatct cccgggcgaa gcccatctcg tgcgtcacca ccaccatggt catgccggac
     3421 atcgccagct tcttcatgac gtcca
//
LOCUS       DAOPZI010000059         3438 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_37007_length_3438_cov_10.688738, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000059 DAOPZI010000000
VERSION     DAOPZI010000059.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 3438)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3438)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3438
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_37007_length_3438_cov_10.688738"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..845)
                     /gene="coaBC"
                     /locus_tag="PKM11_07915"
     CDS             complement(<1..845)
                     /gene="coaBC"
                     /locus_tag="PKM11_07915"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: protein motif:HMM:TIGR00521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015939 - pantothenate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HNX48467.1"
                     /translation="MHPSEAIVGSQSSLLKGKKIVLGITGSIAAVECFELARDLMRHG
                     ATVVPVLTPEAQKLVTPYAMNFATGQEVITELDGRVQHVTLMGDMAGRADLLLIAPST
                     ANTISKIACGIDDTTVTTMATVALGSGVPIVIAPAMHGAMFNNPMVAENIQRLKKAGV
                     EFVGPRMEGKKAKIAVREEIVHAVIRKLSDGKLKGRRLLIIGGSSAESIDDMRIVTNK
                     GTGETALELVKAAYHEGADVELWMGRCTVALPPFVPIKRFESLADLEKLIPNIDHDLV
                     MVPAAL"
     gene            complement(870..1475)
                     /gene="tmk"
                     /locus_tag="PKM11_07920"
     CDS             complement(870..1475)
                     /gene="tmk"
                     /locus_tag="PKM11_07920"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: protein motif:HMM:TIGR00041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HNX48468.1"
                     /translation="MSSKGVFIVLEGIDGTGKSTLSKKLKAFLEEKGRDVVLTAEPTD
                     DWLGAAVRRANQEDLDPRTESLLFTADRCQHTLRIEEQLKQGKVVICDRYYGSTVAYQ
                     GVALEKEMGDNAVSWLLNLNGPVIRHPDVTILLTSDPELAMRRVGDRGELSKFEREEY
                     LDQVQEIYLTLAREAKWTVVDSNGKLADVLESIKKVVQAYV"
     gene            complement(1472..2929)
                     /gene="gcvPB"
                     /locus_tag="PKM11_07925"
     CDS             complement(1472..2929)
                     /gene="gcvPB"
                     /locus_tag="PKM11_07925"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006546 - glycine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HNX48469.1"
                     /translation="MSYRQARYNEPLIFEMKGENDFCLMSEDDVKIPEGMERQDLCLP
                     NVPEMDVVRHYVNLSQMNFGVDNGMYPLGSCTMKYNPKYADKLASLPTVTSVHPCQDE
                     DSIQGALHLLRDLEKALCAISSMDAVTLQPAAGAHGEFTGMLIAKAYHEDREDIRSEV
                     IVPDSAHGTNPASAAMAGFTVIEIPSGPDGCVDLEALGAALSERTAAVMVTNPNTLGL
                     FEKDITKLAEMVHAAGALLYYDGANLNAIMGITSPGLMNFDIVHFNLHKTFATPHGGG
                     GPGAGPVGVKQFLEPYLPVPRIVSEDGKYRLDYERADSIGKVRSMFGNFAVLVRAYSY
                     IIAQGGDGLKEVSQKAVLNSNYLKSKVVPTYEMPFAQLRKHEFVISAKRLAKEKGIHA
                     TDIAKALLDQGFMSPTIYFPSLVEEALMIEPTESESKETLDRFAQALLNIANGDPATV
                     KEAPISTSISRVDEVYAAKELILSWRIYQRKAGLK"
     gene            complement(2926..>3438)
                     /locus_tag="PKM11_07930"
     CDS             complement(2926..>3438)
                     /locus_tag="PKM11_07930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HNX48470.1"
                     /translation="FACRMEHVRKMPGRLIGMTRDQDGRRAFCMTLQTREQHIRRSKA
                     TSNICTNEALLAVAVSAYLGMTGSKGLRSVARINMKRTAELMERVGEIDGFDSPVFSG
                     AHFNEFVVKTPVRPEKLNKLLLRHGIIGGLPLQRHVPRLTDHMLLTATETIRDEDLDH
                     LINALREVAQ"
BASE COUNT          608 a         1045 c         1018 g          767 t
ORIGIN      
        1 agcgccgccg gcaccatgac caggtcgtgg tcgatgttcg gtatgagctt ctccaggtcg
       61 gccaggctct cgaagcgctt tattggaacg aagggcggca gcgcaacggt gcagcggccc
      121 atccacagct cgacgtccgc cccttcgtga taggcagcct taacgagttc cagggccgtt
      181 tcgcccgtgc ccttgttggt cacgatgcgc atgtcgtcaa tgctctctgc cgacgaacca
      241 ccgatgatca gaagacggcg tcctttcagc ttaccatcgg aaagcttgcg gatgacggcg
      301 tgcacgatct cctcgcgcac ggctatcttt gctttctttc cttccatgcg agggccgacg
      361 aactccacgc cggccttctt cagtctttga atgttctcgg cgaccatggg attgttgaac
      421 atcgctccgt gcatggccgg ggcgatgacg atgggaacgc cggagcctag tgcgacagtg
      481 gccatggtgg tcaccgtagt atcgtcaatg ccgcaggcga tcttggaaat ggtgttggct
      541 gtcgacggag ctattagtaa aaggtccgcc cttcccgcca tatcacccat gagggtcacg
      601 tgctgcaccc tgccatccag ttcggttatt acctcttggc cggtggcgaa gttcatggcg
      661 tacggcgtca ctagcttctg cgcctccggc gtcagcaccg gaacgaccgt cgccccgtgg
      721 cgcatcaggt ccctagccaa ctcgaagcac tccacggcgg ctatggaacc ggttatgccc
      781 agcactatct tcttcccttt cagcagggag gactggctac cgacgatagc ctcggagggg
      841 tgcatgctgc taaattcggg cgactcgatt taaacgtatg cctgaacaac tttcttgatc
      901 gattccagca cgtccgcgag cttcccgttg gagtcgacta cggtccattt ggcctccctg
      961 gccagggtca gatagatctc ctgcacctgg tcgagatatt cctcgcgctc gaacttgctc
     1021 agctccccgc gatcgccgac gcggcgcatg gccagctcgg gatcgctggt tagcagtatc
     1081 gtaacgtccg ggtgccttat caccggaccg ttcaggttca ataaccagga gacggcgttg
     1141 tcgcccatct ccttttccag agccacgccc tgataggcga cggtcgaacc gtaatagcga
     1201 tcgcagatga ccaccttgcc ctgcttcagt tgctcttcga tacgcaacgt atgctggcaa
     1261 cggtcggcgg tgaagagcaa agattccgtg cgggggtcga ggtcctcttg gttggcacgg
     1321 cgtaccgccg ctcccagcca atcgtcggtc ggttccgccg tcaggacgac atcccttccc
     1381 ttctcctcca ggaaggcctt gagcttcttg gatagcgtgc tcttacccgt gccgtcgatt
     1441 ccttccagga cgatgaatac gcctttcgag ctcatttcag acccgccttg cgctgatata
     1501 tcctccagct gaggatgagc tccttcgccg cgtacacctc gtccacgcgc gatatcgacg
     1561 tggatatggg cgcttcctta acggtagccg gatctccgtt ggcgatgttc agtaaagctt
     1621 gggcgaagcg atccaacgtt tccttgctct ccgattcggt cggctcgatc atgagcgcct
     1681 cttcgaccag ggaggggaag tagatggtgg gggacatgaa gccctggtcc agtaacgctt
     1741 tggcgatgtc cgtggcgtgt atgcccttct ccttggccaa cctctttgcg gagatgacga
     1801 actcgtgctt tcgtaattga gcgaaaggca tctcgtacgt gggaacgacc ttgctcttca
     1861 gatagttgga attgagcacc gctttctgcg atacctcctt gagaccgtcg cctccctggg
     1921 cgattatgta cgaataggct cgcacgagaa cggcgaagtt gccgaacatg gagcgcacct
     1981 tgccgatgct gtccgcccgt tcgtagtcca gacggtattt gccgtcctcg gagacgatgc
     2041 gtggtacggg aaggtacggc tccaggaact gcttgacgcc caccggtccc gcgcccggcc
     2101 cgccgccgcc atgcggcgtg gcgaacgtct tgtgcagatt gaaatgaacg atgtcgaagt
     2161 tcatgaggcc cggggaggtg atgcccatga tggcgttgag gttcgctccg tcatagtaga
     2221 gaagggcgcc ggcggcgtgc accatctccg ccagtttcgt gatgtccttc tcgaacagcc
     2281 cgagggtgtt ggggttggtg accatcaccg cggccgtccg ttcggatagc gccgcgccta
     2341 gcgcctccaa atcaacgcaa ccgtccggtc cggacgggat ctcgatgacc gtaaaaccgg
     2401 ccatggccgc gctcgccggg ttcgtaccgt gcgccgaatc gggaacgatg acctcgctgc
     2461 gtatatcctc gcggtcctcg tgatacgcct tggcgatgag catcccggtg aactcgccgt
     2521 gcgcgccggc ggccggttga agcgttacgg cgtccatgga ggagatggcg cacagcgcct
     2581 tctccagatc tcgcaggaga tgcagcgctc cttgaatgga atcctcgtcc tggcacggat
     2641 gcacggacgt gacggtcggt aacgacgcca acttgtcggc gtacttgggg ttgtacttca
     2701 tggtgcacga accgagcggg tacattccgt tgtccacacc gaagttcatc tgcgagaggt
     2761 tgacgtagtg gcgaacgacg tccatctccg ggacgttcgg caggcagagg tcctggcgct
     2821 ccattccctc cgggatcttg acgtcatcct cgctcatcag gcagaagtcg ttctcgccct
     2881 tcatctcgaa gatgagcggt tcgttgtacc gagcttggcg atagctcatt gcgccacctc
     2941 ccttagtgcg ttgatgagat ggtccaggtc ctcgtccctg atggtttccg tcgcggttag
     3001 cagcatgtgg tccgtgaggc gcggaacatg gcgttgcagc ggcagcccgc cgatgatgcc
     3061 atgccgcagt aacagcttgt tcagcttctc cggtcttact ggcgttttca ccacgaactc
     3121 attgaagtgg gcgccgctga acaccggcga gtcgaaacca tcgatctcgc ccacccgctc
     3181 cataagttcg gccgtgcgtt tcatgttgat acgggccacg gaacgcaggc ctttggagcc
     3241 ggtcatgccc agatatgcgg ataccgccac ggccaaaagc gcctcgttgg tgcagatgtt
     3301 ggacgtggcc ttgctccggc ggatgtgctg ttccctggtt tgcagggtca tgcagaacgc
     3361 ccggcggccg tcctggtccc tggtcatgcc tatgagccgc ccgggcattt tacggacgtg
     3421 ctccatgcgg caagcgaa
//
LOCUS       DAOPZI010000060         3354 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_38333_length_3354_cov_6.670203, whole genome shotgun sequence.
ACCESSION   DAOPZI010000060 DAOPZI010000000
VERSION     DAOPZI010000060.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 3354)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 3354)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3354
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_38333_length_3354_cov_6.670203"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..298)
                     /locus_tag="PKM11_07935"
     CDS             complement(<1..298)
                     /locus_tag="PKM11_07935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HNX48471.1"
                     /translation="MTTAIHTEDLHVYFEKNHALKGVNMDIEMNKITAIIGPSGCGKS
                     TFIRCINRMNDLIPGCTVKGKVMVDGEDVNDDDVDVVDVRKRIGMVFQKPNPFPK"
     gene            complement(300..1157)
                     /gene="pstA"
                     /locus_tag="PKM11_07940"
     CDS             complement(300..1157)
                     /gene="pstA"
                     /locus_tag="PKM11_07940"
                     /inference="COORDINATES: protein motif:HMM:TIGR00974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HNX48472.1"
                     /translation="MMLSRKATEVAVFSLFRGCAVLVVLALLVLVGYIATGGLERLSI
                     EFLTDMPRRANTQGGIFPAIVGTFYLMLIVLSISVPIGVMSAIYLVEYQQNSLMGRVF
                     RLAVYNLAGVPSIVYGLLGLGIFVAYLGLGFSLISAGLTLSIMTLPLMISSAREAIAA
                     VPSTVREASYALGATKWQTIWHHVLPYALPGIFTGIILSVSRAAGETAPLMLTGVAMS
                     LQRLPDSFFDSFMALPYHVFYMATQSSNLLATRPIQYATALVLLLLVLGMNLFAIVLR
                     KRYRDKYRW"
     gene            complement(1157..2083)
                     /gene="pstC"
                     /locus_tag="PKM11_07945"
     CDS             complement(1157..2083)
                     /gene="pstC"
                     /locus_tag="PKM11_07945"
                     /inference="COORDINATES: protein motif:HMM:TIGR02138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HNX48473.1"
                     /translation="MALKLRKEKGRRLRKNKHLPPREKAIQLALNIATWTSIVALAAV
                     FGELMLGALPAFSSINIIDFFTGTVWNPSHPMYPLYGVVPLFVGTMMVSFGAALIAIP
                     IGLGCSIWLAELASPRVKAVFKPAVEILAGIPSVIFGFFALVILSEWISVVFDPVTKL
                     NALNGAIMLAVMMIPIMVTVAEDAMNAVPRNLREASLALGATRWETIRHVVVPASLSG
                     VVAAIVLAFGRAVGETMTVLMATGNATLLHFDFLRSVQTMTAAIAIDFGEVEFGSDHY
                     HVLFLVGLVLFVMTFIINFLADWVIRRYREEY"
     gene            complement(2157..>3354)
                     /locus_tag="PKM11_07950"
     CDS             complement(2157..>3354)
                     /locus_tag="PKM11_07950"
                     /inference="COORDINATES: protein motif:HMM:TIGR02136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HNX48474.1"
                     /translation="NKNYSANMNMLTGNSAIVNAVQGDSGGVGYVGIGYVSNPTGIDI
                     VSLKADAGSDAYLPTDEQAVLSGDYELARYLYLYTKGTPSGGVKDYLKWIVDPQEGQA
                     IIAEIGFYAIPHNVYEDNLVKMGLTPSAVTITQKGSDTMLELCQIFSEEFNADYPWIT
                     VEVSGGGSGTGISALINGQVDIAQASRAMKSSERTSAIANGVEPVEFRVAIDGIAVIT
                     HQSNGVSVLTEEQLRGIYNGTYTNWNQVGGSDRAITLYGRQSSSGTYVYFQEEILKNK
                     NYSANMNMLTGNSAIVAAVQGDQGGIGYVGIGYANASGIKVLELKESVSDPAYSPMDE
                     DAVLSGDYILSRYLYVYTDGTPTDQVSRWLDWILSVDGGQSVVSEIGFYALPQTVIQE
                     EMAKLG"
BASE COUNT          693 a          973 c          992 g          696 t
ORIGIN      
        1 tcttggggaa cgggttgggc ttctggaaga ccatgccgat gcgtttgcgg acgtcgacca
       61 cgtccacgtc gtcatcgttg acatcctccc cgtccaccat cacctttccc ttcacggtgc
      121 aaccggggat caggtcgttc atgcggttga tacatcgaat gaacgtggac ttgccgcagc
      181 cggacgggcc gatgatggcg gtaatcttgt tcatctcgat gtccatgttc acgcccttga
      241 gggcgtggtt cttctcgaag tatacgtgaa ggtcttcggt gtgaatggct gtggtcattt
      301 taccacctgt acttgtcgcg atatcttttc ctgaggacga tggcgaagag gttcatacct
      361 agcaccaaga gcaatagcac caacgcggtt gcgtactgta tggggcgggt ggccagcagg
      421 ttggaagatt gcgtggccat atagaacaca tgatagggca aggccatgaa gctgtcgaag
      481 aagctgtccg gcagcctctg caaggacatg gccactccag tgagcatgag cggcgctgtc
      541 tccccggccg ccctggacac tgaaaggatt attccggtga atatgcctgg taaagcgtaa
      601 ggcagaacgt gatgccagat ggtctgccat ttggtggccc ccagggcgta ggacgcctct
      661 cgcacagtgc ttggcacggc ggcgatggcc tcccgggcgg acgagatcat cagcggcaat
      721 gtcataatgc tgagcgtaag accggcggag atcagggaga agcccaatcc tagataggcc
      781 acgaatatcc ccagccccag gagtccgtag actatcgacg gcaccccggc caggttgtag
      841 acggccagtc tgaacaccct ccccatcagg gagttctgct ggtactccac tagatatatt
      901 gcggacatga ccccgatcgg cacggatatg gagagcacta tcaacatcag gtagaaagtg
      961 cccactatgg ccgggaatat tccgccctgg gtgttggccc ggcgcggcat gtcagtaagg
     1021 aactcgatgc tcaggcgctc aaggccgccg gtggctatgt aacccaccag caccagcaat
     1081 gccagcacaa cgagcacagc gcaaccccgg aaaaggctga agaccgccac ctcggtggcc
     1141 ttccggctca gcatcatcaa tactcctccc tgtatcgcct aatgacccag tcggccagga
     1201 aattgattat gaaggtcatg acgaagagca ccagcccgac caggaacagg acgtggtaat
     1261 gatccgaacc gaactccacc tcaccgaagt cgatcgctat cgcggcggtc atggtctgga
     1321 ccgaacggag aaagtcgaag tgaagcaagg tggcgttacc ggtggccatc agcacggtca
     1381 tggtctcccc gaccgctctg ccgaaggcca gaacgatggc cgccacaacg ccggacaatg
     1441 aggcgggcac gaccacgtga cgaatggtct cccagcgggt ggcacctaac gccagggacg
     1501 cctcgcgaag gtttctggga accgcgttca tggcgtcctc ggccacggtg accattatcg
     1561 gtatcatcat caccgccagc attatcgccc cgttcagggc gttcaacttg gtcacgggat
     1621 cgaagaccac ggagatccat tccgatagta tgaccagcgc gaagaaaccg aagatgaccg
     1681 acggtatccc tgccagtatc tccacggccg gcttgaacac cgctttcacc ctgggactcg
     1741 cgagctcggc cagccagatc gagcaaccta gcccgattgg tatggctata agggccgccc
     1801 cgaacgacac catcatggtc cctacgaaca atggcacgac cccgtacaac gggtacatcg
     1861 ggtgggaggg gttccatacc gtgccagtga agaaatcgat gatgttaatg gaagagaacg
     1921 ccggtagcgc tcccagcata agctcgccga aaaccgcggc caaagccaca atggaggtcc
     1981 aggtggcgat gttaagcgct agctggatcg ctttctcccg gggcggcagg tgcttgttct
     2041 tgcgcaacct gcgtcctttc tccttacgta acttcaacgc cacgctaacc acgctcctat
     2101 agggtttgga aaatggtttg ttggggtttt gaaagggttc gaggaagggg tttggatcag
     2161 cccagcttgg ccatctcttc ctggatgacc gtctggggga gggcatagaa gcctatctcg
     2221 ctcactacgc tctgaccacc gtcgacgcta agtatccagt ccagccaccg gctgacctgg
     2281 tccgtgggtg tcccgtcggt atagacgtac aggtacctgg acaggatgta gtcgccgcta
     2341 agcaccgcgt cctcgtccat cgggctatac gcggggtccg atacggactc cttcagctcc
     2401 aggactttaa tcccagaggc gttggcgtag ccgataccga catacccgat gccgccctgg
     2461 tctccctgga ccgcggcgac gatggcggag ttgccggtca gcatgttcat gttcgcgctg
     2521 tagttcttgt tcttcaggat ctcttcctgg aagtacacgt aggtaccgga ggaggactgc
     2581 cttccgtaca gggtgatggc ccggtccgaa ccgccgacct ggttccagtt ggtgtacgtc
     2641 ccgttataga tgccgcggag ctgctcctcg gtcaggacgc taactccgtt ggactggtgg
     2701 gttatgacgg ctatcccgtc tatggccacc ctgaactcca caggctcaac gccgttggcg
     2761 atagcggacg ttcgctcgct ggacttcatg gcccgggagg cctgggcgat gtcgacctgg
     2821 ccgtttatca gggcgcttat gccggttccg cttccgccgc cagagacctc aacggtgatc
     2881 cacgggtagt ccgcgttgaa ctcctcggag aaaatctggc acagctcgag catggtgtcg
     2941 gagcccttct gggtgatggt gaccgccgag ggggtcagac ccatcttcac aaggttgtcc
     3001 tcgtagacgt tgtggggaat ggcgtagaaa ccgatctcgg cgattatggc ctgtccctcc
     3061 tggggatcaa ctatccattt caggtaatct ttaacgcctc cgctgggggt gcccttggtg
     3121 tacagataaa ggtacctggc cagctcgtag tcaccgctaa ggacggcctg ttcgtccgtt
     3181 ggaaggtagg cgtcggagcc tgcgtccgcc ttaagggata ctatgtctat gcccgtcggg
     3241 ttgctgacgt agccaatgcc gacgtagccg accccgcccg agtcgccttg gaccgcgttt
     3301 acgatggcgg agttgccggt cagcatgttc atgttcgcgc tgtagttctt gttc
//
LOCUS       DAOPZI010000061         2943 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_46541_length_2943_cov_6.243421, whole genome shotgun sequence.
ACCESSION   DAOPZI010000061 DAOPZI010000000
VERSION     DAOPZI010000061.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2943)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2943)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2943
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_46541_length_2943_cov_6.243421"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..1013
                     /gene="arsB"
                     /locus_tag="PKM11_07955"
     CDS             <1..1013
                     /gene="arsB"
                     /locus_tag="PKM11_07955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008490 - arsenite secondary active
                     transmembrane transporter activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ACR3 family arsenite efflux transporter"
                     /protein_id="HNX48475.1"
                     /translation="GVGLGSLIPDLASYLEDLSVGTTSIPIAIGLILMMYPPLAKVKY
                     EQLGKIARGGETRKMVATSLSLNYIVGPMVMFALAWIFLPDQPEYRIGLILTGVARCI
                     AMVLVWNQLAKGDTEYAAILVALNSIFQIVLYSFYAYFLITVLSDVMSPGAGVAVDIS
                     IISVAISVIIYLGIPFFAGVVTRYTLLPRKGEEWYDRKFMPVMGKISLLALLFTIVVM
                     FSLKGEYILDLPLDVVRVAIPLLFYFLIMFLLSFWVSMRLNFDYPHAASQSFTAASNN
                     FELAIAVAIGVFGIGSGVAFAAVIGPLVEVPVLISLVNLSLYFQRKYYGPDGKGIIKK
                     NE"
     gene            complement(1047..2057)
                     /locus_tag="PKM11_07960"
     CDS             complement(1047..2057)
                     /locus_tag="PKM11_07960"
                     /inference="COORDINATES: protein motif:HMM:NF014010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HNX48476.1"
                     /translation="MNTEIRRVQKTGASTLTVSLPKSWVDSSGLKAGDQVTMAVQLDG
                     TILLDTNMDRRKETFRKEIWTDGEESAEHLTRKLIGAYLVGYNMIEVRSKDRMEPEAK
                     SAIREFSRLAIGPEVVEETANSVIMHDLSDPIELPQEKCVRRMHLIVRSMHADAIEAL
                     CDEDKGLAEDVIDRDTDVDRLYWMAVKQNTLIARDRRLGDRMGINIFESNDLMLVARG
                     IERIGDHAVRISRNALLNAEDEDRLLDVAEIRKLSTESMRVLERGMGSLFRKDIPEAN
                     DVIDDGKNVVKRCEKLGQSNRARDSREAIIINMVMDSIIRSTMYAIDIAEIAINGAMR
                     EN"
     gene            2352..>2943
                     /locus_tag="PKM11_07965"
     CDS             2352..>2943
                     /locus_tag="PKM11_07965"
                     /inference="COORDINATES: protein motif:HMM:NF024257.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HNX48477.1"
                     /translation="MEGKMKLIALGVVAIIIVAAVGTFLLTQNNDDDPEAFVISQKGS
                     DTMLELCQIWAEQYMENNSKATIEVSGGGSGTGISALINGQVDIAQASRAMKSSEKES
                     AIAAGFTPVEFKVAIDGIAIITNDDNTVTNLTMAQLRGMYNGTYTNWNQVGGPNLGIT
                     LYGRQSSSGTYVYFQEEVLKNKNYSANMNMLTGNSAI"
BASE COUNT          611 a          845 c          802 g          685 t
ORIGIN      
        1 tgggtgttgg tctgggatcg ttgatacccg acctggcgtc atatctcgag gacctcagtg
       61 tgggtaccac ctccatccct atcgccatcg gtctcatact gatgatgtac cctcccctgg
      121 ccaaggtcaa gtacgagcag cttggaaaga tcgcccgggg cggcgagacc aggaagatgg
      181 tcgccacctc cctgtcgctc aattacatcg tgggaccgat ggtcatgttc gccctggcct
      241 ggatattcct tcccgatcag cccgagtatc gcattggtct aatactgacc ggggtggcgc
      301 gctgcatcgc catggtcctg gtctggaacc agctggcgaa gggcgacacg gagtacgcgg
      361 cgatattggt ggccttgaac tcgatattcc agatagtcct gtactcgttc tacgcctact
      421 tcctgataac cgttctctcg gatgtgatgt cgcccggcgc cggggtggcg gtggacatct
      481 ccattatttc cgtcgccatc agcgtcatca tctatctcgg tataccgttc ttcgccgggg
      541 tcgtaacgcg atacacgctg cttcccagaa aaggggagga gtggtacgac aggaagttca
      601 tgccggtcat gggaaagata tcgctgctgg cgctgctctt caccatcgtg gttatgttct
      661 cattaaaggg ggagtacata ttggatctgc ctctcgacgt ggtccgggta gcgataccgc
      721 tactgttcta tttcctgatc atgttcctgc tatccttctg ggtatcgatg cgcctgaact
      781 tcgactaccc gcatgccgcg tcccagtcgt tcaccgcggc cagcaacaac ttcgagctgg
      841 ccatcgccgt ggccataggc gtgttcggca tcggctcggg agtggccttc gcggcggtga
      901 tcggtccatt ggtggaagtg ccggtactca tcagcctggt gaacctgtct ctatacttcc
      961 agcgcaagta ctacggtcca gatgggaagg ggatcataaa gaaaaatgaa tgacgcgtga
     1021 accctgggcc aattggacag gcgggcttag ttctcccgca tggccccgtt gatggctatc
     1081 tcggcgatgt cgatggcgta catcgtggaa cggatgatgg agtccatgac catgttgatg
     1141 atgattgcct cccggctgtc tctggcccga ttgctctgac cgagcttctc gcagcgcttg
     1201 acgacgttct ttccatcgtc gatgacatcg ttagcctccg gaatgtcctt acggaacagg
     1261 gagcccattc ccctttccag aacgcgcatc gactccgtac tgagcttccg tatctcggcg
     1321 acgtcgagaa gcctgtcctc gtcctccgcg ttcagcaggg cgttcctgga gatgcggacg
     1381 gcgtgatcgc ctatacgctc tatgccacgc gccaccagca tcaggtcgtt cgattcgaag
     1441 atgttgatgc ccatgcggtc ccccagccgg cggtcccggg ctatgagggt gttctgcttc
     1501 accgccatcc agtaaaggcg gtccacgtcc gtgtcgcggt cgatgacgtc ctccgccaga
     1561 cccttgtcct catcgcatag cgcttcgatg gcatcggcgt gcatgctgcg cactatgagg
     1621 tgcattcgtc tgacgcactt ctcctgcggt agttctatag gatcggaaag gtcgtgcatg
     1681 atgacgctgt tggccgtttc ttcaacgacc tccgggccga tcgccaggcg ggagaactcg
     1741 cgtatggcgc tcttggcctc cggctccatg cggtccttgg agcggacctc tatcatgttg
     1801 tatcccacga gataggcgcc gatgagcttt cgggtcaggt gttcggcgct ctcctcgccg
     1861 tcggtccaga tctcctttcg gaacgtttcc ttgcggcggt ccatgttggt gtccaacagg
     1921 atcgtaccgt caagctgaac ggccatggta acctggtcgc ccgctttaag tccagaggag
     1981 tccacccagc tcttcggcaa cgacactgtc aacgtggaag ctccggtctt ctgcacccgg
     2041 cggatctcgg tgttcatgat acggtcctgt ttcacgagca tagataagtg cttattgtat
     2101 atacaaaact tactagaaat ataaaaaatt ctaatagata ctatttctat atacaaaata
     2161 caagaacata ttctacttag ccaatgtata tattctccac tttggtaact tgttcccgaa
     2221 agaatggaca tagagctagt cggttcagga aaggacatcg ttgtaagacg ccagctcaat
     2281 cctccgtcta tcttcccggg tgaatggacc gcgactctgc gttctttctt tgatgatcaa
     2341 taggtgaaca catggaaggc aaaatgaaat tgatagccct cggcgtcgtc gccataatca
     2401 tagtggccgc cgtcgggaca ttcctgctca cccagaacaa tgatgacgac ccagaggcgt
     2461 tcgtcatctc acagaagggg tctgacacca tgttggagct ctgccagatc tgggccgaac
     2521 agtacatgga gaacaacagc aaggcgacca tcgaggtctc tggcggcgga agcggtaccg
     2581 gcataagcgc tctgattaac ggccaggtcg acatcgccca ggcctcccgg gccatgaagt
     2641 cgtccgagaa ggaaagcgcc atagccgccg ggttcacccc ggtggagttc aaggtggcca
     2701 tagacggcat cgccatcatc accaacgatg acaacaccgt caccaacctg accatggcac
     2761 agctgcgcgg tatgtacaac ggtacgtaca ccaactggaa ccaggtaggc ggacccaacc
     2821 tcgggatcac cctgtacgga aggcaatcct cctccggtac ctacgtgtac ttccaggaag
     2881 aggttcttaa gaacaagaac tacagcgcga acatgaacat gctgaccggc aactccgcca
     2941 tcg
//
LOCUS       DAOPZI010000062         2815 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_49869_length_2815_cov_7.118841, whole genome shotgun sequence.
ACCESSION   DAOPZI010000062 DAOPZI010000000
VERSION     DAOPZI010000062.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2815)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2815)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2815
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_49869_length_2815_cov_7.118841"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            125..1042
                     /locus_tag="PKM11_07970"
     CDS             125..1042
                     /locus_tag="PKM11_07970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-coenzyme M reductase family protein"
                     /protein_id="HNX48478.1"
                     /translation="MYEVLMFDGGVHKIDELLDLIEDLGGFVLQRTQVQVMITLTIAI
                     PAEDRPLIEKKTAELGGKIVEVPLAGTEIAVIGPTLGRHHMPHPICDIAEHLRRYGAI
                     TIVMGLARGRGRKTCQISAAEKAIIEEYDAAIFMLGNFKECVTHEKIDLYKDIQIPVV
                     TVIGPELESLPHCEALVCGVGRKVERMRRSEEIAKLEEIADRVKEVIDKRRKEIEEDP
                     LFVHPSEVKDALEDMGAVQECLRPAPVVLHVDGLRVKIPYKKHLKELEELEVYGRKLK
                     NIATISDCRLGDSTIIRIKTKAEVEGKVR"
     gene            1052..1492
                     /locus_tag="PKM11_07975"
     CDS             1052..1492
                     /locus_tag="PKM11_07975"
                     /inference="COORDINATES: protein motif:HMM:NF014088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HNX48479.1"
                     /translation="MRSSPGAYVLVAYLPAPAVICAGGLGEIFLEEGHYLYCGSAQAG
                     LMPRLARHMRVEKKKHWHIDSLTCRAVVIGALTFAGAKDTECLLAATVASVPGIEPIG
                     DGFGSSDCGCPTHLFRLRNDVPLSVVLDVIRSSFSKARLNGQSI"
     gene            1525..1749
                     /locus_tag="PKM11_07980"
     CDS             1525..1749
                     /locus_tag="PKM11_07980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48480.1"
                     /translation="MFGSRKSKLEAKIKQLNALRAEYRSELDEAERLHKKRELGEDEL
                     QRIRRRCQAKMDDIAEKVRAARSELDSLKE"
     gene            2568..>2815
                     /locus_tag="PKM11_07985"
     CDS             2568..>2815
                     /locus_tag="PKM11_07985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48481.1"
                     /translation="MSAETESVSKAMAPVVSKLQDAIGRENVKTSKMERLLYSHDLAP
                     LPSLAQIAFKNVPDVVVRPHTTEDVVKIVKIAAEEKVP"
BASE COUNT          654 a          765 c          839 g          557 t
ORIGIN      
        1 ggaacgagta cttcaacgac aacgtcatga ccatcgtggc cacggagcac gggatgaccg
       61 tcgacttcat agcggaagcg cagaaggtgc atgccaacat gatcaagggc ccggaggagg
      121 actgatgtac gaagttctga tgttcgacgg cggggtccac aagatagatg aactgctcga
      181 tctgatcgag gacctgggcg gtttcgttct gcagcgcacc caggtgcagg tcatgatcac
      241 cctgaccata gccattccgg ccgaggaccg cccgctcatc gagaagaaga cggcggagct
      301 cggcggcaag atcgtcgagg tgccgttggc ggggacggag atagcggtca tcggtccgac
      361 cctgggcagg catcacatgc cccaccccat ctgtgacatc gccgagcacc tgcgaaggta
      421 tggcgccatc accatcgtca tgggtctggc ccgcggccgc ggacgcaaaa cgtgtcagat
      481 atcggcagcg gagaaggcca tcatcgagga gtatgacgcg gccatattca tgctcggcaa
      541 tttcaaggag tgcgtcaccc acgagaagat cgacctctac aaggacatcc agatcccggt
      601 cgttaccgta ataggcccgg agctggaatc gcttccgcac tgcgaggcgc tggtatgcgg
      661 cgtaggacgg aaggtcgaac ggatgcggcg ctccgaggag atagcgaagc tcgaggagat
      721 cgccgaccgg gtgaaggagg tcatcgacaa gcgcaggaag gagatcgagg aggatcccct
      781 gttcgtccat ccgtccgagg tcaaggacgc cctggaggac atgggcgcgg tgcaggaatg
      841 cctgcgcccg gctccggtgg tccttcacgt ggacggtctg cgggtcaaga tcccctacaa
      901 gaagcacctc aaggagctgg aggagctgga ggtctacggc cggaagctga agaacatcgc
      961 caccatctcc gactgccgtc tcggggacag caccatcatc cgcatcaaga ccaaggccga
     1021 agtggagggc aaggtccgct agcgggggaa catgcgctcc tcgccgggtg cttacgtgct
     1081 ggtcgcatat cttccggcac cggcggtcat ttgcgccggt ggcctgggtg agattttcct
     1141 tgaagaaggt cattatctct actgcggttc cgcccaggcc ggtctgatgc ccagattggc
     1201 caggcacatg cgggtcgaaa agaaaaagca ctggcacatc gattccttga cctgccgagc
     1261 ggtggtcatc ggcgcgctca ccttcgcggg agccaaggat acggaatgcc ttctagcggc
     1321 gacggtcgcc tcggtcccgg gcatcgagcc gataggcgac ggtttcggct cttcggactg
     1381 cggatgcccc acgcatcttt tccgcttgag gaacgatgtt ccgttgtccg tcgtccttga
     1441 tgttatccgt tcctcgttct ccaaggcacg tcttaacgga caatctattt agacgatgca
     1501 ggccgatata attctgggag aggcatgttc ggttccagga aatccaagct cgaggccaag
     1561 atcaagcagc tcaacgccct gcgcgccgaa taccgttccg aattggacga ggcggaacgc
     1621 cttcacaaga agagggagtt gggcgaggac gagctgcagc gcatacgccg aagatgccag
     1681 gcgaagatgg atgatatcgc tgaaaaagtt cgggccgccc ggtcggaatt ggattcgctc
     1741 aaggagtgac ccgctccctt attttgtgcg tccagccata aaaacaatct atttatactg
     1801 agaacgacca agtataatat tgcccgtgga atggagaggg aaggacctgc ggatgaatct
     1861 ccgcccgcct tcatcgacca aaacggtccg ccgtgcgtga gcgcagtgaa cagttgcgtg
     1921 gtctcgccgg ttcccccgcg ccctatgtgc gatcggcggg agatgaaggg gtggtcgccc
     1981 gaggaacttc tccactttga ggaatgggtc ggaccgaagg tcgccttact cctccccctc
     2041 cgcccgggca cttttgacct gcattaattc accttctacg taaattttat tattatataa
     2101 tgaataatat tctggctaat gcattaaacg ggcaaataaa taaatactag acaaggtaat
     2161 agtaattatt gcccgagtcg gaaaagctgg ggggaaacca ggatggatcc agcatgattt
     2221 gaggatcatg cccgtaggaa aaggtcctgt ccgcgcgctc cttcgggggc gggttcgccc
     2281 atccgcttcc tgacttaaga cgggaaagca gtgtgacgaa tggcgatcga gacccttcgg
     2341 gatcttgaaa gctaggtagg acgtcatcga ggtgacgaac cacccatctg cagatgtggg
     2401 ttcgccaagt agggacgaag taccttcgag caccgatctc gggcaccctt ctcaacctct
     2461 tattttaaca atccacattt ttcatgtatg gctcaggaat aggtttaaaa tacttcaccg
     2521 acttcacggt ataatctcat ttatatccta gtaacagagg tcttcacatg tcagctgaga
     2581 cagaaagtgt gagcaaggct atggcgccag tggtgtccaa gctgcaagat gcgatcggaa
     2641 gggagaacgt aaagaccagc aagatggaga ggctcctgta cagccacgac ctcgcccctc
     2701 tacccagtct ggcccagatc gccttcaaga acgttccgga cgtcgtggtc cggcctcata
     2761 ccaccgagga cgtggtcaag atagtcaaga tcgctgcgga ggagaaggtc ccgat
//
LOCUS       DAOPZI010000063         2733 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_52128_length_2733_cov_9.108663, whole genome shotgun sequence.
ACCESSION   DAOPZI010000063 DAOPZI010000000
VERSION     DAOPZI010000063.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2733)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2733)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2733
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_52128_length_2733_cov_9.108663"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..262
                     /locus_tag="PKM11_07990"
     CDS             <1..262
                     /locus_tag="PKM11_07990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48482.1"
                     /translation="MLGEDEMRLMRTDGKVYNVSVRNYAYYHFSQDIMMDMFEGGLLR
                     YDQERSVIGNGSVEFELDGRWYLRVIVPVGDQPHVFTMETRD"
     gene            complement(425..769)
                     /locus_tag="PKM11_07995"
     CDS             complement(425..769)
                     /locus_tag="PKM11_07995"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48483.1"
                     /translation="MAYRPNRNKSRAGKPNNYRDRDAPSTRVGMLNQRRLGEFRYDVR
                     ELFVNNQMDPDLAATFLASIMAKGSRQSIRDTKDFVREQHAAGIITKEVMDGLIYYLD
                     RYTKYQSQQTGE"
     gene            complement(884..1354)
                     /locus_tag="PKM11_08000"
     CDS             complement(884..1354)
                     /locus_tag="PKM11_08000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HNX48484.1"
                     /translation="MNDCRMRAKKAVDELEKQMGGYVPPTLHHIKNNHPALAVIIGDM
                     DKVINTDGALDRKTKRLIALACVSVRMCEGCIYPQAKVAKNCGATREEIMEALNIAVL
                     TGGVPSWSTARTGITELFAEWDAEDAEKAKLGAKAVPKKVSVQPGAAKKPAKKK"
     gene            complement(1451..2185)
                     /gene="phoU"
                     /locus_tag="PKM11_08005"
     CDS             complement(1451..2185)
                     /gene="phoU"
                     /locus_tag="PKM11_08005"
                     /inference="COORDINATES: protein motif:HMM:TIGR02135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0051049 - regulation of transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HNX48485.1"
                     /translation="MTPRTTFTFEMEELNKEITEMANASRTAFEKAVQMITDMDFSLR
                     EEVRALDKRIYQLNEQIDRHCLDIIALHSPVAGDLRLIAACLKMVEDLNRFGRYAMDI
                     AELIDDFEEGKAFKRFEALRTMSCLVVGMVDDAVYSFLQRDAEKASHLHERDDAVDAL
                     YDTIFREILTYMMEDPRKITVGIDLILVARYMERVADHSCNIGEYVYHMVTGDRLDPT
                     LRTGDVDVSCAKIFEHPDPRSDLDLK"
     gene            complement(2185..>2733)
                     /locus_tag="PKM11_08010"
     CDS             complement(2185..>2733)
                     /locus_tag="PKM11_08010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019176528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HNX48486.1"
                     /translation="DVRKRIGMVFQKPNPFPKSIYENVAYGPRLHGVAETIDGKVRRR
                     KHTKKELDEIVEHSIRRAALWDEVKDRLDKSGTSLSGGQQQRLCIARTLAVGPEIILF
                     DEPCSALDPIATAKIEDLLVDLKKDYTVVIVTHSMQQASRISDRTAFFYLGDLIEMGD
                     TKQIFEKPSKELTEQYITGRMG"
BASE COUNT          530 a          763 c          799 g          641 t
ORIGIN      
        1 catgctcggg gaggacgaga tgcgtctgat gcgcacggac ggcaaggtct acaacgtgtc
       61 ggtgaggaac tacgcttact atcatttcag tcaggacatc atgatggaca tgttcgaggg
      121 cggcctgttg cgctatgacc aggagaggtc ggtcatcggc aatggcagcg tggagttcga
      181 actggatgga cggtggtatc ttcgggtcat agtgccggtc ggcgaccaac cccacgtgtt
      241 cacgatggag acgagggatt gagaaagtaa ggttccgctg ctcacgacga tagcgaccaa
      301 acgatgattg gacgagaggg accactctgc ggattacgca tcagaagtta gtgcccctcg
      361 gaacatagca ggccgggcag gtcgctagaa tgaacgacca cgcccctaaa ataagaggag
      421 gatatcactc gccggtctgc tggctctggt acttggtgta gcggtccaaa taataaatta
      481 aaccgtccat gacctctttg gtgatgatgc cggcggcatg ctgctcacgg acgaagtcct
      541 tggtgtcccg gatgctctgg cgtgagcctt tggccattat gctggccagg aacgtagcgg
      601 ctagatcggg gtccatctgg ttgttgacga acagctcccg gacgtcgtac ctgaactcgc
      661 ccagtcggcg ttggttaagc atgccaacgc gggtcgacgg cgcgtcccgg tcccggtagt
      721 tgttcggttt ccccgctctg ctcttgttcc ggttaggtcg atacgccaaa gtgatttctc
      781 cgatgtgaag tgatgggaag atattattaa tactttgcca aaataagaat aatttattta
      841 aaatataaag aagaaaaaaa ggtttttcag ggcggaaact ggcctacttc ttttttgccg
      901 gtttcttggc cgcgccgggc tgcaccgaga ccttcttcgg gacggccttc gcgccaagct
      961 tggccttctc cgcgtcctcg gcgtcccact ccgcgaacag ctcggtgatc ccggtgcgcg
     1021 cggtggacca ggacggaact ccgccagtga gcacggcgat gttcagcgcc tccatgatct
     1081 cctcacgagt ggcaccgcag ttcttggcca ccttggcctg gggatagatg catccctcgc
     1141 acatgcgcac ggaaacgcag gccaatgcga tcaaacgctt ggtcttgcgg tccagagcgc
     1201 cgtcggtgtt gatgaccttg tccatgtccc cgattattac cgccagggcc gggtggttgt
     1261 tcttgatgtg gtgcagcgtc ggcggaacgt agccgcccat ctgcttctcc agctcgtcaa
     1321 cggccttctt ggccctcatc ctgcaatcgt tcattgggac gaactatgat gctgaatgga
     1381 tattagcctt gtgccttgag ttaaaaatat gagtaaaggg tttggaaagg gtttaggagc
     1441 gttctcatcg tcacttcagg tccagatcgg agcgggggtc gggatgctcg aatattttgg
     1501 cgcaagacac atccacgtcc ccggtcctca gcgtcggatc gagacggtcc ccggtcacca
     1561 tgtggtagac gtattcgccg atattgcagg agtggtcggc caccctttcc atgtagcgag
     1621 ccactaggat caggtcgatg cccacggtga tcttccgggg gtcctccatc atgtaagtca
     1681 gtatctcccg gaatatggtg tcgtacagcg cgtccaccgc gtcgtcccgc tcgtgcaggt
     1741 gagacgcttt ttcagcgtcc ctctgcagga acgagtacac cgcgtcgtcc accatgccta
     1801 cgacgagaca cgacatggtg cgcagcgcct cgaagcgctt gaaggccttc ccttcttcga
     1861 aatcatctat tagctcggca atgtccatgg cgtaccgccc gaagcggttg aggtcctcca
     1921 ccatcttcag gcaggcggct atcaatcgca ggtcgccggc gaccggcgaa tgcagggcga
     1981 tgatgtccag gcagtgccgg tcgatctgct cgttgagctg gtagatgcgt ttgtccagcg
     2041 cccgtacctc ctcgcgcagg gagaagtcca tgtcggtgat catctggacc gctttttcga
     2101 atgcggtacg agaggcgttg gccatctcgg ttatctcctt gttaagctcc tccatctcaa
     2161 atgtgaacgt ggttcgcggg gtcatcagcc catcctcccg gttatgtact gctccgttag
     2221 ctccttcgaa ggtttttcaa atatctgctt ggtatcgccc atctctataa ggtcgcccag
     2281 gtagaagaag gccgtgcgat ccgaaatgcg cgacgcctgc tgcatgctgt gcgtcacgat
     2341 gaccaccgtg taatccttct tcagatcgac cagcaggtcc tcgatcttgg cggtggctat
     2401 gggatcgaga gcggagcacg gttcgtcgaa caggattatt tccggaccga ccgctaacgt
     2461 ccgagcgatg cacagcctct gctgctgccc gcccgatagc gaagtgccgc tcttgtccag
     2521 gcggtccttg acctcgtccc acagggccgc ccggcgtatg gaatgctcga ctatctcgtc
     2581 cagttccttc ttggtgtgct tgcgccggcg aacctttccg tcgatcgtct cggcgacacc
     2641 gtgcagtcgc ggtccatagg ccacgttctc atagatgctc ttggggaacg ggttgggctt
     2701 ctggaagacc atgccgatgc gtttgcggac gtc
//
LOCUS       DAOPZI010000064         2637 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_55084_length_2637_cov_6.396204, whole genome shotgun sequence.
ACCESSION   DAOPZI010000064 DAOPZI010000000
VERSION     DAOPZI010000064.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2637)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2637)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2637
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_55084_length_2637_cov_6.396204"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..256
                     /locus_tag="PKM11_08015"
     CDS             <1..256
                     /locus_tag="PKM11_08015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48487.1"
                     /translation="IVQHRHGEGGDDDNGHDGDSDDGDLLIHLKFTLAIKIEIWYKAF
                     LSIKVKFILFVQILSHIAHLYPVKSTVLENRSTNTSDNNF"
     gene            314..763
                     /locus_tag="PKM11_08020"
     CDS             314..763
                     /locus_tag="PKM11_08020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015505511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HNX48488.1"
                     /translation="MFELNVISNTPLTPIEDIKEASLEFLKQIGYISKGYDPKTDVEN
                     IQESIPYRLFTECFMGNLNRVWAVEELSAYLGTTKPTVYRHLNKLKAIDVLEDVSMDI
                     GGQRKKGYRIRYGDLGKAWSFTEANVDMAMQSYRRTVEHLQRLAKEE"
     gene            766..1026
                     /locus_tag="PKM11_08025"
     CDS             766..1026
                     /locus_tag="PKM11_08025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48489.1"
                     /translation="MDEKFPTRLTKGSRYHLVIGTGGGSTLDMDGEFVGYLQYGSDVA
                     LTMLMASGSLRVVPSRSVVYLDILDSKEEKEERSKESGVYFG"
     gene            1047..2603
                     /locus_tag="PKM11_08030"
     CDS             1047..2603
                     /locus_tag="PKM11_08030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019178580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine(34) 5-carboxymethylaminomethyl
                     modification radical SAM/GNAT enzyme Elp3"
                     /protein_id="HNX48490.1"
                     /translation="MDRRQEYHQHIIRLLLSGEISNKDELQRKKIKLSGEYGLPGVPK
                     NSETLALVPKDKLSDVLEILRRKPVRTLSGVAVVAVMTSPAPCPHGKCTYCPGGVENN
                     SPQSYTGKEPAARRAADNEFDPYRQVLSRITQLSTIGHYTDKVDLIIMGGTFTSRPEE
                     YREWFIKRCFDAFNGSDSLSLEAAHSMNEEAEHRVIGMTVETRPDAFTEEAARECMRL
                     GATRVELGVQILDDEILTSVNRGHGVAEVVEATRIAKDLGLKVCYHVMPGLPGSDPEK
                     DIDSFRQIFDDRRFRPDMIKIYPTLVVKGTKLHEDWMAGRYSPYTTAEAVHVIAEMKK
                     LVPEYVRIQRIQRDIPVPLIEAGVDKGHLRELVKELLALQGKGCRCIRCREVGLLGIN
                     EIDPRELVPKVITYEASGGREEFISMVLENNALAGYVRLRKPEGETALVRELKVFGRM
                     ARLGERDGEWQHIGLGGRLLAMAETSAAEDGYSSVKVTSGVGVRGYYASRGYEKALPH
                     MEKRLASDKD"
BASE COUNT          611 a          730 c          788 g          508 t
ORIGIN      
        1 cattgttcaa catcgtcacg gcgaaggcgg cgatgatgac aatggccacg acggcgacag
       61 cgatgatggc gatcttctta tccatctgaa attcacctta gcgattaaaa tcgaaatatg
      121 gtataaagcg tttttgtcta ttaaggtaaa atttatcctg tttgtacaaa ttcttagcca
      181 tattgcccat ctgtaccctg ttaagtcgac ggtgttagaa aacaggtcta caaacacatc
      241 tgacaataat ttttaagtaa gcaagtttac aaattcttta ttatccgagc atcttatcgc
      301 tcatacgaat attatgttcg agctgaacgt gataagcaac acccctctca ctccgatcga
      361 agatatcaaa gaggcttcat tggagttcct caagcagatc ggctacatct ccaaaggata
      421 tgatccgaag acggacgtgg agaacattca ggagagcatt ccctatcgtc tcttcaccga
      481 atgtttcatg ggcaacctga accgggtctg ggcggtggag gagctctccg cttatctggg
      541 caccaccaag cccaccgtct accggcatct caacaagctc aaggccatcg atgtactgga
      601 ggacgtctcc atggacatcg gcgggcagag gaagaagggc taccgcatca gatacggcga
      661 tctggggaag gcctggagct tcaccgaggc caacgtggac atggcgatgc aatcctaccg
      721 tagaacggtg gagcacctgc agcgcctggc caaggaggag taggaatgga tgagaagttc
      781 cccaccaggc tgaccaaggg ctcccgatat catctggtca tcgggaccgg cggcgggtcc
      841 accctggaca tggacgggga gttcgtagga tacctgcagt atgggagcga tgtggcgttg
      901 accatgctca tggcctccgg ctcactgagg gtggtgccgt cccgttccgt cgtctatctg
      961 gacatactcg attccaagga agagaaggaa gagcgctcca aggagagcgg ggtctacttc
     1021 ggttaaggtc ccaggaacgg aattagatgg accggcgcca ggaatatcat cagcatatca
     1081 ttcgcctgct cctctccggg gagatatcca acaaggacga gctgcagcgg aagaagatca
     1141 agctcagcgg agagtacggt ctcccgggcg ttcccaagaa ctcggagacg ctcgccctgg
     1201 tccccaagga caagctgtcc gatgttctgg agatacttcg ccgcaagcct gtacggacgt
     1261 taagcggggt ggcggtggtg gcggtcatga cgtctccggc tccctgtccg cacggcaagt
     1321 gcacctactg ccctggcggg gtggagaaca actccccgca atcgtacacc ggaaaggagc
     1381 cggccgcccg gcgcgccgca gataacgagt tcgatcctta ccgtcaagtt ctatctcgaa
     1441 taacccagct atcgaccatc ggtcattaca ccgacaaggt cgacctcata atcatgggtg
     1501 ggacgttcac ctcccgcccc gaagagtacc gggaatggtt catcaagcgc tgcttcgacg
     1561 ccttcaacgg ctccgactcg ctcagcctgg aagcggcgca ctctatgaac gaggaggccg
     1621 agcaccgcgt catcgggatg accgtggaga cccggccgga cgccttcacc gaggaagcgg
     1681 ccagggaatg catgcggctg ggggcgacgc gcgtcgagct aggcgttcag atactggacg
     1741 atgagatact cacctcggtg aatagagggc acggggtggc agaggtggtc gaggccaccc
     1801 gcatcgccaa ggacctgggg ctgaaggtct gctatcacgt catgcccggc cttccggggt
     1861 ccgatccgga gaaggacatc gactcgttcc ggcagatctt cgatgaccgc cgcttccgtc
     1921 cggacatgat caagatatac cctacgctgg tggtcaaggg caccaagctc catgaggact
     1981 ggatggccgg aagatacagt ccatacacca ccgccgaggc ggtgcacgtc atcgccgaga
     2041 tgaagaagct ggtgcccgag tacgtacgca tccagcgcat ccagagggac attcccgttc
     2101 cgctcatcga agcgggggtg gacaaaggtc atctccgtga gctggtcaaa gagcttctcg
     2161 ccctccaagg aaaaggctgc cgctgcatcc gctgccgcga ggtagggctg ctgggcatca
     2221 acgagatcga cccccgggaa ctggtcccca aggtcatcac ctatgaggcg tccgggggcc
     2281 gggaagagtt catatccatg gtgctggaga acaacgccct ggccggctac gttcgcctcc
     2341 ggaagccgga aggcgagacc gctctggtcc gggagctgaa ggtgttcggg cgcatggcgc
     2401 gtctgggcga aagggatggg gaatggcagc atatcggcct aggcggaaga ttgctggcca
     2461 tggccgagac gtcggccgcc gaggatgggt attcttcggt caaggtcacc agcggcgttg
     2521 gtgttcgcgg ctattacgcc tctaggggtt atgagaaggc gctaccccac atggaaaaac
     2581 gacttgccag cgacaaggat taatccccga cgggcaatat ccccccaggg gatgcgt
//
LOCUS       DAOPZI010000065         2482 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_60434_length_2482_cov_7.100536, whole genome shotgun sequence.
ACCESSION   DAOPZI010000065 DAOPZI010000000
VERSION     DAOPZI010000065.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2482)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2482)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2482
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_60434_length_2482_cov_7.100536"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            164..1357
                     /locus_tag="PKM11_08035"
     CDS             164..1357
                     /locus_tag="PKM11_08035"
                     /inference="COORDINATES: protein motif:HMM:NF012382.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HNX48491.1"
                     /translation="MRDPTSFLKKEYQDLVDQSLDWRIAKLQGASTPWCNVDGKRVLM
                     FCSNNYLSLSNHPHLKELAKRAVETHGVGSGSVRPIAGTMDLHLELEERLAKFKGRPA
                     SLVYQTGFAANSGLIPQLAGKGDLIISDELNHGSIIDGVRLTSAERAIYKHCDTDDLA
                     LKLEEAERKEVPYRRILIITDGVFSMDGDMAPLDRIARLAKDHGAMLYVDDAHGEGVL
                     GEGGRGIVSHFGLDHNAVQVEMGTFSKAFGVVGGHVSGSTDLKNFALNKSRTWLLSGS
                     HPPAVAAACIGAIDVLENEPQHVRNLWKRTDRFRKAMRDLGFDTGRSVTPIIPVMVGD
                     SAKAKRLSERLYQEGIFALPIIFPMVARDKARIRTIMNAALSDEDLDYAVSKFELIGR
                     ELGII"
     gene            1387..2058
                     /locus_tag="PKM11_08040"
     CDS             1387..2058
                     /locus_tag="PKM11_08040"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48492.1"
                     /translation="MFEHISPTQAAVEFFYGLLMAMTLSNTLRLALLGTSPADVVFVV
                     SVAIFGCNTAWGIADGAVSLLTSHFQNMYYYRKVKQIKEGADLEAARELATEVLSEAL
                     SELQEDVLDEETRRHMAELTVRSIKRQEISEPVVGRSQWMTALWCLIMNVAAALPFIA
                     IYQLGLFLGLNLVTLVANVAGAVLLFFLGRFLDRRLGDGNGRTGLVMVGLGMLMLVII
                     VALGG"
     gene            2108..>2482
                     /locus_tag="PKM11_08045"
     CDS             2108..>2482
                     /locus_tag="PKM11_08045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48493.1"
                     /translation="MFAYNLLVTFHENQKGRSELEVRDLLGELGTSVEKLETCDVEGV
                     FLIRVAGEAKVLVSQLKRLCHEDPVGFQYTHHWVPIERWTTSKKEEIRKNAVELGRSI
                     GTDETWMMHLHKRHMPEHYDDLI"
BASE COUNT          533 a          698 c          801 g          450 t
ORIGIN      
        1 tggacgattc ccgggccgcg caggactggg gctggagggc ggaatggagc ctggaacgtc
       61 tggctgacga catgttcatg aagttgcgca agcgcaaagc ccaaggcaat ctctagcgag
      121 gatagattaa tccgaccgct agtcgctcca ggaccaggat aacatgagag accccacctc
      181 gttcctcaag aaggagtacc aggaccttgt cgatcagtcg ttggactggc gcatcgccaa
      241 gctgcagggg gccagcacgc catggtgcaa cgtggacggc aagagggtgc tcatgttctg
      301 ctccaataac tatctcagcc tgagcaacca cccgcacctc aaggaactgg ccaagagagc
      361 ggtcgagacg cacggggtcg gttccggttc cgtgcggccc atcgccggca ccatggacct
      421 gcacctggag ctggaggaac gtttggccaa gttcaaaggc cgccccgcat cgctcgtcta
      481 ccaaacgggc ttcgccgcca actccggact gatacctcag ctggccggga agggggacct
      541 gataatttcc gacgagctga atcacggcag cataatcgac ggcgtccgcc taacatcggc
      601 ggaaagggcc atttataaac actgcgacac ggacgaccta gcattgaagc tggaggaggc
      661 ggagcgcaag gaagtgcctt accgccgcat cctgatcata accgacgggg tgttctccat
      721 ggacggggac atggcccccc tggacaggat cgccagactg gccaaggacc atggtgcgat
      781 gctctacgtg gacgatgcgc acggcgaggg ggtgctgggc gagggcggac gaggaatagt
      841 ctcgcacttc ggcctggacc acaacgccgt tcaggtggag atgggtacgt tctcgaaggc
      901 cttcggcgtc gtcggtggac acgtctccgg ttccacggat ctcaagaact tcgctctgaa
      961 caagtcccgg acgtggctgc tcagcggttc ccaccctccg gcggtggccg ccgcctgcat
     1021 aggagcgata gatgtcctgg agaacgagcc acagcacgtg cgtaacctat ggaagagaac
     1081 ggaccgcttc cgcaaggcca tgcgggacct gggcttcgat actggacgtt ccgtaacgcc
     1141 catcataccg gtgatggtcg gcgacagcgc gaaagcgaaa agacttagcg agaggctgta
     1201 ccaggaaggg atattcgccc tgccgatcat attccccatg gtggcccggg acaaggcgcg
     1261 catacgcacg ataatgaacg ccgccctgag cgatgaggac cttgattatg ccgtcagcaa
     1321 gttcgaactg atcggccgag agctggggat aatctgagct cggacgaaag cctgttggac
     1381 cggctgatgt tcgagcacat cagccccacg caggcggcgg tggagttctt ctacgggctg
     1441 ctgatggcca tgacccttag caacaccttg cgcttggcgt tgctgggaac ctcgcccgca
     1501 gacgtggtct tcgtcgtttc cgtggccatc ttcggctgca acaccgcctg gggcatcgcc
     1561 gacggggcgg tcagcctcct cacctcgcat ttccagaaca tgtactatta ccggaaggtc
     1621 aagcagatca aggaaggggc ggacctcgag gcggcgagag agctggcgac ggaggtcctt
     1681 tcggaagcac tctccgagct gcaggaggac gtactggacg aggaaacgcg ccggcacatg
     1741 gccgagctga cggtacggtc gatcaagcgc caggagatat cggaacccgt ggtgggccgc
     1801 tcgcaatgga tgaccgccct atggtgcctg atcatgaacg tcgcggccgc ccttccattc
     1861 attgcgattt atcaattggg gttgttcctg ggcctcaacc tggtcaccct cgtcgccaac
     1921 gtcgccggcg cggtgctgtt gttcttcctg ggacggttcc tggaccgtag gctcggcgac
     1981 ggcaacggac ggacgggact ggtgatggtc ggcctgggca tgctgatgct ggtgatcatc
     2041 gtggccttgg gcggttgagg gcaagttatt tgatggcgca cgctaaagtg ttcacgaggt
     2101 gcgaaaaatg ttcgcctaca acctcctggt gacctttcac gaaaatcaga agggtcgctc
     2161 cgagctcgag gttcgggacc tattggggga actggggacc agcgtggaaa aactggagac
     2221 ctgcgatgtg gaaggagtgt tcctgatacg ggtggccggg gaggccaagg tgctggtctc
     2281 ccagctcaag cgcctatgcc atgaggaccc ggtggggttc cagtacaccc atcactgggt
     2341 gcctatcgag agatggacga cttctaaaaa ggaagagatc aggaagaacg cggtggaact
     2401 cggcaggagc atcggaacgg acgagacctg gatgatgcac ctgcacaagc gccatatgcc
     2461 ggagcattac gacgatctga ta
//
LOCUS       DAOPZI010000066         2225 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_71572_length_2225_cov_8.388018, whole genome shotgun sequence.
ACCESSION   DAOPZI010000066 DAOPZI010000000
VERSION     DAOPZI010000066.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2225)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_71572_length_2225_cov_8.388018"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..299
                     /locus_tag="PKM11_08050"
     CDS             <1..299
                     /locus_tag="PKM11_08050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="isocitrate/isopropylmalate family dehydrogenase"
                     /protein_id="HNX48494.1"
                     /translation="AMFEAIHGSAPRMVDEGRAQYADPSSMIKATAMLLNHVGYVEKA
                     KKLEMALDLCTQFEKKKKITGRSDGATGEEFGRYVLETVERKDLEEAWKEAKGD"
     gene            complement(313..1164)
                     /locus_tag="PKM11_08055"
     CDS             complement(313..1164)
                     /locus_tag="PKM11_08055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48495.1"
                     /translation="MIQVMLLALMLVMTSGAAFYIGGENEGPVPTLPRDTYMMLTYEV
                     EGVFNGTPVNGSFGVQMLTGGIGSGFSYSWPYNITGNLGPLATLPGFIFGLDCFLVRS
                     TMDTPWGEKQGMLFIGQTFNWNGSQGVVFTYKGVDTGLAYRIDLVAPEAKATYSLAAI
                     NITGMEDLDLSVRNDLGDLTAARHLEDGYSTILSGSGTWGLLEALDDESYRISLNATD
                     YAFMVFGEQEILSMAAGGDFSPVGEWSMNGNGSREFVITDQMVFFYLDPIVGSSGADG
                     LLVITML"
     gene            complement(1327..1467)
                     /locus_tag="PKM11_08060"
     CDS             complement(1327..1467)
                     /locus_tag="PKM11_08060"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48496.1"
                     /translation="MDKGSRQSIRDTKDFVREQHAAGIITKEVMDGLIYYLDRYTKYQ
                     SQ"
     gene            1572..>2225
                     /locus_tag="PKM11_08065"
     CDS             1572..>2225
                     /locus_tag="PKM11_08065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48497.1"
                     /translation="MAEISLSQSVLAAFIIVMLISVAFMSHAEEDDEGGEFTRAQGVF
                     TYSVSMDMDGAVHNGTYVLDTLSREDELTWENESFAQLIDEGRQNGTAFMFLHTWQIG
                     FFPTMIDKVSMETPWGEKKLDRSLILWPDMEGGFLMNVVYGGGNTLTNYRQDIISERW
                     RATFLLTDLVGTDIASEDREWSDRAIDIGNSRQHYGKEWSMLGEDEMRLMRTDGKVYN
                     "
BASE COUNT          513 a          612 c          652 g          448 t
ORIGIN      
        1 acgccatgtt cgaggccata cacggctccg ccccgcgcat ggtggacgaa ggtcgcgcgc
       61 agtacgctga ccccagctcc atgatcaagg ccaccgccat gctgctgaac catgtcggtt
      121 acgtagaaaa ggcgaagaaa ctggagatgg ccctggacct ctgcacccag ttcgaaaaga
      181 agaaaaagat aactggacgt tccgacggtg ccaccggcga ggagttcggt cgctacgttc
      241 tggagacggt ggaaaggaag gacctggaag aggcctggaa ggaagcgaag ggagattgag
      301 gttcgggcgt cctcacagca tcgttatcac caggaggccg tccgccccgg aagagccgac
      361 gatcggatcc aggtagaaga acaccatctg atcggtgatt acgaactccc tgctcccgtt
      421 gccgttcatc gaccattccc cgacgggact gaagtccccg cctgccgcca tggacagtat
      481 ctcctgctcc ccgaagacca tgaaggcgta gtcggtggcg ttcaatgata tgcggtagga
      541 ttcatcatca agagcctcca aaagacccca tgtcccggac cctgacaata tggtgctgta
      601 tccgtcctcc aaatgacgag cggcggtgag atcgccaagg tcgttccgga cgctgaggtc
      661 caggtcctcc atcccggtga tgttgatggc ggccagagag taggtcgcct tggcctccgg
      721 ggcgaccagg tctatacggt acgccaggcc ggtgtccacc cccttgtaag tgaacaccac
      781 gccctggctc ccgttccaat tgaacgtctg gccgatgaaa agcatcccct gcttctcccc
      841 ccagggggtg tccatcgtcg accgcaccag gaagcagtcc aatccgaata taaacccggg
      901 cagggtcgcc aagggaccca ggttcccggt gatgttatag ggccagctgt aagagaagcc
      961 gctgccgatc cctccagtga gcatctgtac cccgaaggac ccgttcaccg gcgttccgtt
     1021 aaaaacccct tcgacctcgt acgtgagcat catgtacgtg tccctgggca atgttggcac
     1081 cggaccttcg ttctccccgc ctatgtagaa ggccgccccg ctggtcatca ccagcattaa
     1141 agcgagcagc atcacctgga tcatcttcgc ctgttccgac agatccccca ccttaggaaa
     1201 attgacctgc gtaagagagc ttaaatctat tgcttgaacg atataaatcg agcgaccgga
     1261 aaaatggatg cggaccttgg gaccgtcatc cgagggcggg gcgatggaag aagatcactc
     1321 gccggcctac tggctctggt acttggtgta gcggtccaag taatagatta aaccgtccat
     1381 gacctctttg gtgattatgc cggcggcatg ctgctcacgg acgaagtcct tggtgtcccg
     1441 gatgctctgg cgtgagcctt tgtccatgac gctagccagc aattgctgag gtaaacccct
     1501 ttagaatcat tttatagaag cgtgagaaca aatataagta accctgaatg attatttgga
     1561 ttggggaatt tatggcggag atatcattgt cgcagtcggt gctggcggcc ttcatcatcg
     1621 tcatgctgat cagcgtggcc tttatgtccc acgccgaaga ggatgacgaa ggcggggaat
     1681 tcacgcgggc gcagggtgtg ttcacctata gcgtcagcat ggacatggac ggcgcggtgc
     1741 ataacggaac ctatgtgctt gataccctgt cgagagagga tgagctgacg tgggagaacg
     1801 aaagctttgc gcaactgatc gatgagggcc gccagaacgg aacggcattc atgtttttac
     1861 acacctggca gatcggattc ttccccacta tgatcgataa ggtgagcatg gaaactccct
     1921 ggggcgagaa gaagctggac cgtagcttaa ttctgtggcc tgatatggag ggcgggttcc
     1981 ttatgaacgt cgtctacggg ggcggaaaca ccctgaccaa ctatcgccag gacatcattt
     2041 cggaaagatg gcgggcgact ttcctgctga cggacttggt tggaacggac atcgccagcg
     2101 aggaccggga atggtcggac agggcgatcg atatcggcaa ctcccgccag cactacggga
     2161 aggagtggtc catgctcggg gaggacgaga tgcgtctgat gcgcacggac ggcaaggtct
     2221 acaac
//
LOCUS       DAOPZI010000067         2008 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_83728_length_2008_cov_9.403482, whole genome shotgun sequence.
ACCESSION   DAOPZI010000067 DAOPZI010000000
VERSION     DAOPZI010000067.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 2008)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 2008)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2008
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_83728_length_2008_cov_9.403482"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            238..1629
                     /gene="cysS"
                     /locus_tag="PKM11_08070"
     CDS             238..1629
                     /gene="cysS"
                     /locus_tag="PKM11_08070"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015504919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HNX48498.1"
                     /translation="MSLQIYNTMAKAKQEFRPIEDGKVKMYVCGVTVYDDVHMGHARF
                     LVVFDMVSRYLRYKGYDVKMVINFTDVDDKIIKRANEENVDALVVSARCIQSFFRDSD
                     ALRVKRADFYPKASETIPEIIGMVEDIIAAGYGYVTPDGSVYYDVSKATEYGKLSGNK
                     LEEMQSGARIEVDEIKRNPMDFCLWKAAKPGEISWDSPWGKGRPGWHIECSAMVRKLL
                     GTTIDIHGGGNDLIFPHHENEILQSESVTKKPLANYWMHNGMLQVSDAKMSKSLKNFF
                     SVKDILARYPPEVVRFYLLNTHYRGPLVYGESALDEAAVSLKRIHNTYGSLKTYVPRG
                     QDGAEELITKAKAGFLTEMDDDFNSRSALSYLFDVAREANRLMDTGELSADGVANIMG
                     FMNELDGIFDILPEEKKGDEKLDDVMLLLIDIRKELRKRKMYDLSDLIRDRLQESGIK
                     IEDTAEGAKWKLI"
     gene            1614..>2008
                     /locus_tag="PKM11_08075"
     CDS             1614..>2008
                     /locus_tag="PKM11_08075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48499.1"
                     /translation="MEADLSPVEKKAVLICGGTVKVAKDFRPPFRLSRSTAGPGAGSA
                     SLVLAFVGLRVKKAISREEGEFELVGEPEGYSLLRNGQPFLSEVELRPVLYHSPEQAF
                     FNLGQECIFDCLFCTSRKLSKDVAKDLDL"
BASE COUNT          476 a          547 c          569 g          416 t
ORIGIN      
        1 ggggagcccg tctacacggt catatcgcga gctttcccta taagtcccgg tcttcgcctc
       61 atatttcttc tgcggatatc ctattggcga tgttaattgg acgatatcgt cctggattag
      121 gcgatcaatt atctcgtaca gttcatcact agggcagaca tctatcctgg cgcctcattt
      181 cctacagcgg cgggttcaaa acaattatat tatgcggatg agagatgagg ggtgctcatg
      241 tcgctgcaga tctacaacac catggccaag gccaagcagg agttcagacc tatcgaggac
      301 ggcaaggtca agatgtatgt ctgtggtgtc accgtttacg acgatgtgca catgggccac
      361 gcccggttcc tggtggtctt cgacatggtc tccagatacc tgagatacaa gggatacgat
      421 gtcaagatgg tcatcaactt caccgacgtg gacgacaaga tcatcaagag ggcgaacgag
      481 gagaacgtgg acgctctcgt cgtgtcggca agatgcatcc aatccttctt tcgcgattct
      541 gacgcgctcc gtgtgaagcg cgctgatttc tatcccaagg ccagtgagac catcccggag
      601 atcatcggca tggtcgagga tatcatcgcg gcaggttacg gttatgtcac cccggacgga
      661 agcgtttact acgatgtcag taaagccacc gaatatggca agctctccgg aaacaagctg
      721 gaagagatgc agtccggagc ccgcatcgag gttgacgaga tcaagcgcaa ccccatggac
      781 ttctgcctgt ggaaggccgc caagcccggg gagatatcct gggattcgcc gtggggcaaa
      841 ggacggccgg ggtggcacat cgagtgctcg gccatggttc gcaagctgct cgggacaact
      901 atcgacattc acggcggcgg taacgacctc atattcccgc atcacgagaa cgagatactg
      961 caatcggaat ccgtcaccaa gaaacccttg gccaactatt ggatgcacaa cgggatgctg
     1021 caggtgtcgg acgccaagat gtccaagtcc ctgaagaact tcttttccgt gaaagatatc
     1081 ctcgcccggt acccaccgga ggtcgttcgg ttctatctgc tcaacactca ttaccgcgga
     1141 cctctcgtct acggcgaatc ggctctggac gaagcggcgg tatcattgaa gcgcattcac
     1201 aacacgtacg gatcactgaa gacctatgtg cccagaggtc aggatggcgc cgaggaactg
     1261 ataaccaagg ccaaggccgg cttcctgacg gagatggacg acgatttcaa ctcccgcagc
     1321 gctctctcgt acctgttcga tgtggccagg gaagccaacc ggctcatgga caccggagag
     1381 ctcagtgccg atggcgttgc gaacatcatg ggcttcatga acgaactgga cgggatattc
     1441 gatatccttc ccgaagagaa gaagggcgac gagaagctgg acgatgtcat gctgcttctg
     1501 atcgacattc gtaaggagct cagaaagcgc aagatgtacg atctgtccga cctcatccgc
     1561 gaccgcctgc aggaatccgg tataaagata gaggacaccg ccgaaggtgc gaaatggaag
     1621 ctgatctgag cccggtcgag aagaaggccg tcctgatctg cggcgggaca gtcaaggtgg
     1681 caaaggactt ccgtcctccg ttccgcctga gccgctccac cgccggacca ggcgccggct
     1741 ccgcatcgct tgtactagcg ttcgtaggat tgcgggtcaa gaaggccatc tcccgcgaag
     1801 agggggagtt cgaactggtc ggcgaaccgg aaggttactc cctgctcagg aacggacagc
     1861 ctttcctttc agaagtggaa ctgagaccag ttctctatca ttcaccggag caggccttct
     1921 tcaacctggg tcaggaatgc atattcgact gtctgttctg cacttcccga aaattgagca
     1981 aggacgtggc caaggacctg gacctcga
//
LOCUS       DAOPZI010000068         1742 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_104630_length_1742_cov_12.109662, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000068 DAOPZI010000000
VERSION     DAOPZI010000068.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1742)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1742)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1742
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_104630_length_1742_cov_12.109662"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..410)
                     /locus_tag="PKM11_08080"
     CDS             complement(<1..410)
                     /locus_tag="PKM11_08080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48500.1"
                     /translation="MVPLYWGMDALRLLGNSALMMTLSLITALALGGFPDGIGLTNSN
                     IAMITLVIMMSLSLTNLQLKGLKVRDHASSVGRAFLLSMVLASGATVLISFFFEGDLR
                     AGWVIAAAVPSAISVVPFTYLMKGDLEPTLVSTAA"
     gene            complement(486..>1742)
                     /gene="hcp"
                     /locus_tag="PKM11_08085"
                     /gene_synonym="priS"
     CDS             complement(486..>1742)
                     /gene="hcp"
                     /locus_tag="PKM11_08085"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019177827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016661 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HNX48501.1"
                     /translation="VACTTRGVCGKNEDIQSQQEMLIYGLKGIAAYAYHARILGKKDE
                     NVDAFMHEALFKTLTNVDFSAKDHWDLLLKAGMMNYRAMEMLQEGNTEHFGDPTPTSV
                     FTGVKKGPGILVTGHDLLDLEALLKQTEGTGVNVYTHGEMLPAHAYPKLKAYKHLVGN
                     YGSAWQKQKTEFAEFGGPILATTNCVLIPPESYKDRLYTTGITALDNVKHLERNDYSA
                     IIEHAKRIGDLAERQGINLMTGFHHKAVLSLAPQIIDAVKTGKIKHFFLIGGCDGATP
                     GRDYYTELAEKVPKDCVILTLACGKYRFNDRDFGTIEGTGIPRLLDVGQCNDTYSALQ
                     IAIALSKAFNVGVNELPLSIVLSWFEQKAVAIVYTLLALGVKNVRVGPTAPAFISPNN
                     WKFIADNFNWMPIGNVDEDLKAMLKK"
BASE COUNT          326 a          473 c          558 g          385 t
ORIGIN      
        1 gccgccgtgg agaccagggt cggctccagg tcccccttca tgaggtaggt gaatggaacg
       61 acggatatcg ccgaaggcac cgccgcggcg atgacccagc cggcccgcag gtccccttcg
      121 aagaaaaagg atatcagaac ggtggccccg gaggccagca ccatggagag gaggaacgcc
      181 cggccgacgg aggaggcgtg gtcccgcacc ttcaatccct tcagctggag attggtgagt
      241 gaaagggaca tcatgatcac cagggtgatc atggcgatgt tgctgttagt gaggccgatc
      301 ccatcaggga acccaccaag cgccagggcg gtgatgagcg acagcgtcat catgagagcg
      361 ctgttcccca gtaaccgcag ggcgtccatg ccccagtaaa ggggaaccat gattaacggt
      421 tttctaggtg atcgatcgca tttaagaaag gaaaaggaaa tggttgaaag gggtttttat
      481 gctctttact tcttgagcat cgccttgagg tcctcatcca cgttgccgat gggcatccag
      541 ttgaagttat cggcgatgaa cttccagttg ttgggggaga tgaacgccgg ggcggtcggt
      601 cccacgcgga cgttctttac gccgagcgcg aggagcgtgt agacgatggc caccgccttc
      661 tgctcgaacc aggagagcac gatgctcagc ggcagttcgt tgacgccgac gttgaaggct
      721 ttcgataggg ctatggcgat ctgcagagcc gagtaggtat cgttgcactg acctacgtcc
      781 agcagccgcg ggatgccggt gccctcgatg gtcccgaagt ccctgtcgtt gaagcggtac
      841 ttgccgcaag ctaacgtcaa aataacgcag tccttgggca ccttctccgc cagttcggtg
      901 taatagtccc ttccgggggt ggcgccgtcg cagccgccga tcaggaagaa gtgctttatc
      961 ttgccagtct tgacggcatc gattatttgc ggcgctaacg aaagaacggc cttgtggtgg
     1021 aacccggtca tgaggttgat gccctgtcgt tcggcgagat cgccgatgcg cttggcgtgc
     1081 tcgatgatgg cggagtaatc gttcctctcc aggtgcttga cgttgtccag ggcggttatc
     1141 ccggtggtgt acaggcggtc cttgtagctc tcgggcggga tcagcacgca gttggtggtg
     1201 gcgaggatgg gaccgccgaa ctccgcgaac tcggtcttct gcttctgcca ggccgagccg
     1261 tagttgccga ccaggtgctt gtatgctttc agtttagggt aggcgtgggc cgggagcatc
     1321 tcgccgtgcg tgtagacgtt gacgccggtg ccctcggtct gcttcagcaa tgcttccaga
     1381 tcaagcaggt cgtgtccggt tacgagtata ccaggtccct tcttgacgcc ggtgaagacg
     1441 ctcgtggggg tcggatctcc gaagtgctcg gtgttgccct cctgcagcat ctccatggcg
     1501 cggtagttca tcattcccgc tttcagcagc aggtcccagt ggtccttggc ggagaagtcc
     1561 acgttggtca aggtcttgaa caaagcctcg tgcatgaagg cgtcgacgtt ctcgtccttc
     1621 ttgcctagga ttcgagcgtg gtaagcgtag gcggctattc ccttcaagcc gtagatgagc
     1681 atctcctgct ggctctggat gtcttcgttc tttccgcaga cgccgcgggt cgtgcaggcg
     1741 ac
//
LOCUS       DAOPZI010000069         1682 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_110549_length_1682_cov_8.234173, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000069 DAOPZI010000000
VERSION     DAOPZI010000069.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1682)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1682)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1682
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_110549_length_1682_cov_8.234173"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..916
                     /locus_tag="PKM11_08090"
     CDS             <1..916
                     /locus_tag="PKM11_08090"
                     /inference="COORDINATES: protein motif:HMM:NF024258.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HNX48502.1"
                     /translation="KDNKAAKDSILQDEVIGVIGKMSRRDRKLILKDLIRPDVPFSSG
                     MEVTDSTAQVAFMSDVHVGSNTFLEERWKNMIEWMRDEAKDLDIRYVVIPGDCVDGVG
                     VFPGQEEELVIEDIIDQYRALAEHLKDVPDDIRIVMQPGNHDMVRPAEPQPALSEEVA
                     KLFDSNILQIGNPAYLKIEGRTILSYHGKSFDDLVNGIKGLSYSQPLKAMEEMLKRRH
                     LAPSYGGKTPFAPERKDYMVIDEVPDIFVTGHVHGAGVSFYNGIRLINASTWQDQTSF
                     QKMHNFVPDPAKLVLAHLGTGKMSVADF"
     gene            955..1521
                     /locus_tag="PKM11_08095"
     CDS             955..1521
                     /locus_tag="PKM11_08095"
                     /inference="COORDINATES: protein motif:HMM:NF012696.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HNX48503.1"
                     /translation="MYTTPPKDEDGANIFIESVLNGNRSWMTNYRRPPVNGSAKAVVL
                     TCMDSRIPPLEMLGLTPGEVFIIRNAGNAINNDSLRSLLICLTVMECRNVLVVGHSSC
                     GMRSSGDLDERVLDTVDIAALSEALDEEIEDARSWLGFYEPHEKEWATRQSAYLREMV
                     KRVMPGIPVTVRSALYHLENGYLEMLDQ"
BASE COUNT          369 a          486 c          522 g          305 t
ORIGIN      
        1 caaggacaac aaggcggcca aggactccat cctgcaggac gaggtcatcg gcgtgatcgg
       61 taagatgtcc cggcgggacc ggaagctgat actcaaggac cttatacgtc cggacgtccc
      121 gttcagttcc ggcatggagg ttacggattc cacggcccag gtggccttca tgtccgacgt
      181 gcacgtcggc agcaacacct tcctggagga acgctggaag aacatgatag agtggatgag
      241 ggacgaggcc aaggacctgg acatccgcta cgtcgtcatt cccggcgatt gcgtggacgg
      301 agtcggagtc ttcccgggcc aggaggagga gctggtcatc gaggacatca tcgatcagta
      361 ccgcgctctg gccgagcacc tcaaagacgt tccggacgac attcggatcg tgatgcaacc
      421 ggggaaccac gacatggtcc gtccggcgga accgcagccg gcgctgagcg aggaggtggc
      481 caagctgttc gactcgaaca tcctgcagat aggcaacccc gcttacctca agatagaggg
      541 tcggacgata ctgtcgtacc atggcaagag cttcgacgac ctggtcaacg ggatcaaggg
      601 actttcatac tcccagccgc tgaaggccat ggaggagatg ctcaagaggc ggcatctcgc
      661 gccgtcgtac ggcggcaaga cgcccttcgc cccggagcgg aaggattaca tggtcattga
      721 cgaggtgccg gacatcttcg tcaccgggca tgtgcacggc gccggggttt ccttctacaa
      781 cgggatccgg ctcatcaacg cctccacctg gcaggaccag acctccttcc agaagatgca
      841 taacttcgta ccggacccgg cgaaactggt cctggcgcat ctcggcaccg gcaagatgtc
      901 cgtggccgac ttctgaggaa accttgaaat aacggtgctt gggctaaggg ggtaatgtac
      961 accaccccgc cgaaggacga ggatggcgcc aatattttca ttgagagcgt tctgaacggt
     1021 aaccgttcct ggatgaccaa ttaccgccgt cctccggtga acggctccgc gaaagcggtg
     1081 gtgctcacct gcatggactc ccgcataccg ccactggaga tgctgggact gacccccgga
     1141 gaggtgttca tcatcaggaa cgccgggaac gccatcaaca acgattcact acgttctttg
     1201 ctcatctgcc tcacggtgat ggagtgccgc aacgtactgg tggtcgggca cagcagctgc
     1261 ggcatgcggt cctcggggga cctggacgag cgagtgttgg acacggtgga catcgcggcc
     1321 ctctccgagg ccctggacga agagatagag gacgcccggt cctggctggg gttctacgaa
     1381 ccgcacgaga aggaatgggc gaccaggcag tccgcctacc tgcgggagat ggtgaagagg
     1441 gtcatgcccg ggattccagt gaccgtaagg tccgccctgt atcacctaga gaacgggtac
     1501 ctggagatgc tggatcagta gtcccagaag aggaccatga gcccgtaacc tagcagtagc
     1561 attaaaagtg agatgagcca ggcgtacctg accagcctgg cccttttttc cggagtatca
     1621 aagagttttt cgagcatcat ccgcgcgctt ccgccttctg cttgacgcgc ttcagccgga
     1681 ag
//
LOCUS       DAOPZI010000070         1668 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_111997_length_1668_cov_8.895226, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000070 DAOPZI010000000
VERSION     DAOPZI010000070.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1668)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1668)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1668
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_111997_length_1668_cov_8.895226"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..954)
                     /gene="trkA"
                     /locus_tag="PKM11_08100"
     CDS             complement(<1..954)
                     /gene="trkA"
                     /locus_tag="PKM11_08100"
                     /inference="COORDINATES: protein motif:HMM:NF007039.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HNX48504.1"
                     /translation="MHVIVVGAGNVGYTIARMLSKQHSVLVIEDDLKRYDYVVNHLNV
                     GALNGNGASPKVLKSVINEDTNLLLAVTERDETNIFTCMMAKQINPKLVTVARVRNPD
                     YIEGAMASKFLNVDHIISPEYLTAEKLMRIALMENSIGVETVPSLGIELAMFKVSGKK
                     EGVVMVPLRELPIPEECKILIIHRGKQIIVPTVNDVLMKGDQVTIVGKGKAVADFNRM
                     LGILREPRDMVIVGGGIVGEHLATLLEKEKISVKLIENDEDRCRILAKQLSKTVIIND
                     DGSDPSVLRNENVSMADVLICATENEEDNLLASLIGTHLGVS"
     gene            complement(1078..>1668)
                     /locus_tag="PKM11_08105"
     CDS             complement(1078..>1668)
                     /locus_tag="PKM11_08105"
                     /inference="COORDINATES: protein motif:HMM:NF015558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HNX48505.1"
                     /translation="APVIDAKAHNTHAVIGVISVLGLIGVFVVPWLASIAGLDAAQAE
                     VLIGGSLHEVGNVIPAADLYHNALGGEDVAALVLAYKMIRVAMLVVVAYVLARLFRGE
                     GRTSGTRMPGFLIAFVIVAALMSLLIMVLPEMGGEVRSIVVSSSASLLTVAMAGVGLS
                     MNLRQTVKIGRKLMPVAALVWVVQLGLLFALTFLLV"
BASE COUNT          333 a          516 c          475 g          344 t
ORIGIN      
        1 ggagaccccc aggtgcgtgc cgatgaggga cgctaacaga ttgtcctcct cgttctccgt
       61 ggcgcagatg agaacgtcgg ccatgctgac gttctcgttc ctcagcacgg acgggtcgga
      121 accgtcgtcg ttgatgatca ccgtcttgct caattgcttg gccaggatgc ggcagcggtc
      181 ctcgtcgttc tcgatgagct taacggatat cttctccttc tccagaagcg tggccagatg
      241 ctctccgact atacctccgc cgacgatgac catgtcccgg ggctccctga gtatacccag
      301 catgcggttg aaatcggcca ccgccttacc ttttccaacg atggtcacct ggtcgccctt
      361 catgaggacg tcgttgacgg tggggacgat tatctgcttg ccgcggtgga tgatgagtat
      421 cttgcactcc tcggggatgg gcagttcccg caggggcacc atcaccactc cctccttctt
      481 cccgctgacc ttgaacatgg ccagctctat gcctagggaa ggaacggtct ccacgccgat
      541 ggagttctcc atgagagcga tgcgcatcag cttctcggcg gtgaggtatt ccggcgagat
      601 tatgtgatcg acgttcagga acttggaggc catggccccc tcgatgtaat cgggattgcg
      661 aaccctggcc acggtgacca gtttgggatt gatctgcttg gccatcatgc aggtgaagat
      721 gttcgtttcg tccctctccg tcacagccag gagaaggttg gtgtcctcgt tgatgacgct
      781 cttcagaact ttagggctag cgccgttgcc gttgagcgct ccgacgttca gatggttgac
      841 cacgtagtcg tagcgcttga ggtcgtcctc gatgaccagg acagagtgct gcttggaaag
      901 catcctggct atggtatagc ccacgttccc cgcgcccact acaatgacgt gcatccctca
      961 acgctccatg tgccattggc tattgcccga ataccggata aggaacgctt tacccattaa
     1021 agatatgttt gctaatcgcc gccggcacct gaccgtccga taagctggac agatggttca
     1081 caccaacaaa aacgtcaatg cgaacaggag cccgagctgg accacccata ccagggcggc
     1141 cacgggcatc agttttcgac cgatcttcac ggtctggcga aggttcatgg aaagcccgac
     1201 cccggccatg gccacggtga gcagggaggc ggaagatgac accacgatcg aacgaacctc
     1261 cccacccatt tccggaagga ccatgatcag cagcgacatc aaggcggcca cgatcacgaa
     1321 ggcgatcagg aatccgggca tcctcgtgcc ggaggtcctg ccttcgcccc ggaagagcct
     1381 ggccaggacg taagccacca cgaccagcat ggccacccgg atcatcttgt aggccagcac
     1441 cagggcggcc acgtcctcgc cgcctagagc gttgtggtac aggtcggccg ccggtatgac
     1501 gttcccgacc tcgtgcagtg agccgcctat cagcacttcc gcctgggcgg cgtccagtcc
     1561 ggcgatcgac gctaaccagg gaacgacgaa cacccctatc agaccgagaa cgctgatgac
     1621 cccgatcacc gcgtgcgtgt tgtgcgcctt ggcgtcaatg accggcgc
//
LOCUS       DAOPZI010000071         1611 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_118430_length_1611_cov_10.611825, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000071 DAOPZI010000000
VERSION     DAOPZI010000071.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1611)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1611)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1611
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_118430_length_1611_cov_10.611825"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            complement(<1..902)
                     /locus_tag="PKM11_08110"
     CDS             complement(<1..902)
                     /locus_tag="PKM11_08110"
                     /inference="COORDINATES: protein motif:HMM:NF027681.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HNX48506.1"
                     /translation="MSKKIMVLGATGQIGSELILELRKRFGGKNVIGVGHSRTPSKDI
                     LESGPYETGNVLDVKRIEELCEKHDVGTIYHLAAVLSGVGEKDPQFAWDLNMNGLLNV
                     LEVARKRNVKLFWPSSIAVFGNNCPRLSTPQDTVLQPTTMYGVTKVAGELLCDYYHRK
                     YGVDVRSVRYAGIISAETPPGGGTTDFAVAIFYEAVRKNRYTCFVNERTVLPMMYMPD
                     CINAAIGIMEAPAERITTRLGYNLNGLNFSAAELAEIVKARSPGFVISYEPDFRQAIA
                     DSWPDSMDDSRAAQDWGWRAEWSL"
     gene            complement(1024..>1611)
                     /locus_tag="PKM11_08115"
     CDS             complement(1024..>1611)
                     /locus_tag="PKM11_08115"
                     /inference="COORDINATES: protein motif:HMM:NF015155.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MMPL family transporter"
                     /protein_id="HNX48507.1"
                     /translation="DSEFSKVEILVVVGIFVILMIVLGSILLPAFAVLSIAMSISWAF
                     ALTYFVFGTLLSLPVLWLIPLILFVMLMGIGIDYNIFILTRIREEIHKGKDTKEAVVD
                     AVDWTGGIITALALIMAGAFGAMMLSSNAMLQEFGFALTVAILLDAMVVRTYIVPAGL
                     AVMGKKAWWAPGRLQREGREEKMRLKAEKKAQKKQ"
BASE COUNT          327 a          477 c          479 g          328 t
ORIGIN      
        1 tccaggctcc attccgccct ccagccccag tcctgcgcgg cccgggaatc gtccatggag
       61 tccggccagg agtcagcgat cgcttggcgg aaatcaggtt cgtagctgat gacgaacccc
      121 gggctgcggg ccttgacgat ctcggccagc tccgcggcgg aaaagttcag tccgttgagg
      181 ttgtacccca gccgggtggt gatcctttcg gcaggagcct ccatgatccc gatggcggcg
      241 ttgatgcagt ccggcatgta catcatcggt aggaccgttc gttcgttcac gaagcaggtg
      301 taacggtttt tccgcaccgc ctcatagaaa atcgcgacgg caaaatcggt cgtgccgccg
      361 cccggaggcg tctcagcgct gatgatgccc gcgtaacgga cgctgcgcac gtccactcca
      421 tacttgcggt gatagtaatc gcagagcagc tctccggcca ccttggtcac gccatacatg
      481 gtggtgggtt gcagcacggt gtcctgcggt gtgctcaggc gaggacagtt gttcccgaag
      541 acggcgatgg aggaaggcca gaacaatttg acgttacgtt tcctggccac ctccagaacg
      601 ttgagcaggc cgttcatgtt gaggtcccag gcgaactggg ggtccttttc cccaaccccg
      661 gagaggacag ccgccaggtg atagatcgtt cccacgtcgt gcttttcgca aagctcttcg
      721 atgcgcttga cgtccagaac gttaccggtc tcgtacggtc cagattccag gatgtccttg
      781 gagggcgtac ggctgtgacc tacgccgatg acgttcttcc cgccgaaccg cttcctcagt
      841 tccaaaatga gctccgagcc tatctggccg gtagcgccca ggaccatgat cttcttgctc
      901 aagggaacac cttcgttacg aacgttccgg gaacgcctgc tgagaatata agctatggaa
      961 tgacaaggtt tggcatacga aaaaatagaa aagggcggcc gggtgggccg ccctggttgg
     1021 agtttactgc ttcttctgag ccttcttttc ggccttcagg cgcatctttt cctcgcggcc
     1081 ctccctttgc aggcggccag gggcccacca ggccttcttg cccataacgg ccaggccggc
     1141 aggtacgatg taggtgcgca ccaccatggc gtccaagagg atggccacgg tcagagcgaa
     1201 accgaactcc tgcagcatgg cgttgctgga gagcatcatg gccccgaacg cgccggccat
     1261 gatcagggcc agagcggtta tgatgccgcc ggtccagtcc accgcgtcga ccaccgcctc
     1321 cttggtgtcc ttacccttgt ggatctcctc gcgtatacgg gtgaggatga agatgttgta
     1381 gtcgatacct atgcccatca gcatgacgaa cagtatcagc ggtatgagcc acagcacagg
     1441 cagactgagc aaggtgccga acacgaaata ggtgagggcg aaggcccagc tgatgctcat
     1501 ggctattgac aggaccgcga aggccgggag cagtatcgat ccaagcacta tcatcaggat
     1561 gacgaagatg ccgacgacca ccagtatctc gaccttggag aactcggagt c
//
LOCUS       DAOPZI010000072         1597 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_120030_length_1597_cov_7.730869, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000072 DAOPZI010000000
VERSION     DAOPZI010000072.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1597)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_120030_length_1597_cov_7.730869"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            31..651
                     /locus_tag="PKM11_08120"
     CDS             31..651
                     /locus_tag="PKM11_08120"
                     /inference="COORDINATES: protein motif:HMM:NF017959.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HNX48508.1"
                     /translation="MRRRELAGVLLFVAIIQFAFLANISQILYDGYSIEETLLSDLGV
                     WEQPSALVFNASLVIFGILGISIGAVLWPDKKLNFIPLLFVLCGVGMFIMAAFPISIE
                     WAHDVGAFLSFVLIAVAALCCYWTFPGPFRYLSLVIGIIGFFTEITYKTGIYFGLGVA
                     GSERMIIFPLFLWMAAFAAVLFYSDENAPRDSLLDRFFAWTVSKLS"
     gene            698..931
                     /locus_tag="PKM11_08125"
     CDS             698..931
                     /locus_tag="PKM11_08125"
                     /inference="COORDINATES: protein motif:HMM:NF021452.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2164 domain-containing protein"
                     /protein_id="HNX48509.1"
                     /translation="MKGKERIVLEREKRDDLVKVLIAYFKEERGEEIGRLAAGILLDL
                     IVEKIAPEFYNQGVIDSCAYMNERVEDMQSLLL"
     gene            complement(947..1348)
                     /locus_tag="PKM11_08130"
     CDS             complement(947..1348)
                     /locus_tag="PKM11_08130"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48510.1"
                     /translation="MREETKVVLEMVARKRAEKIKEASPGLETQLTMDDSGLRAALQV
                     LKDGELVRLEFIESTLTAGKQAHFPDYLEVARGIGSLGILFPESKFSRDLASSIFQSV
                     LKEARQGTDREMTFLGFVYDDKGNIKKVDLP"
BASE COUNT          300 a          467 c          463 g          367 t
ORIGIN      
        1 gtttaattca actccgacgt tcaccaacgc gtgagacgca gggagctcgc tggcgtatta
       61 cttttcgtgg ccataatcca gttcgcgttc ctggccaaca tcagccagat actgtatgat
      121 ggttacagca tagaggagac cttgctctcc gacctggggg tctgggagca gccttccgcc
      181 ctggtgttca acgcctccct ggtcatattc gggatactgg gcatcagcat aggagcggtc
      241 ctgtggccgg acaagaagct gaacttcatt ccacttctct tcgtgctgtg cggcgtcggc
      301 atgttcatca tggccgcctt cccgatatct atcgagtggg cgcatgacgt cggggcgttc
      361 ctgtcgttcg tgctcatcgc cgtggcggcc ctgtgctgct actggacctt tcccgggccg
      421 ttccggtacc tctctctcgt cataggcatc atcggcttct tcaccgagat aacctacaag
      481 acggggatct acttcgggct gggcgtggcc ggctcggagc gtatgatcat cttcccgctg
      541 ttcctctgga tggccgcctt cgccgccgtt ctgttctact cggacgagaa cgcgcctagg
      601 gatagtttat tggaccgctt cttcgcctgg accgtcagca agctcagttg agggaagttt
      661 atcattccct ccgctcatcg gggaacggga gacggtcatg aaggggaagg agcgcatcgt
      721 tctggagcgg gagaagcgag acgacttggt gaaggtcttg atcgcctact tcaaggagga
      781 gcggggcgag gagataggcc gactggccgc cgggatattg ctcgatctta tcgtcgagaa
      841 gatagccccg gagttctaca accagggcgt tatcgactcg tgcgcctaca tgaacgaacg
      901 cgtagaggac atgcagtcgc tgctgctgtg agcctggtcg tccattttaa ggcaggtcca
      961 ccttcttgat gttgccctta tcatcgtaaa cgaaaccgag gaaggtcatc tcccggtccg
     1021 ttccctgcct cgcctccttt agcacgctct ggaatatcga cgaggccagg tccctcgaga
     1081 acttggactc ggggaacaat atgcctagcg atccgatgcc tctggcgacc tccagataat
     1141 cggggaagtg cgcctgcttt ccggcggtca acgtggactc gatgaactcc aatcgcacca
     1201 gctcgccgtc cttgagcacc tgcagggcgg cccttaggcc ggaatcgtcc atggtcagct
     1261 gcgtctccag cccgggggag gcctccttga tcttttccgc tctcttcctg gccaccatct
     1321 ccaggaccac cttggtctcc tcgcgcatga tggtgattac acctcgtggg acatcatcct
     1381 atgccttagg cggggcagat aacggtcgat aggaacaggc gcgcgctcga acagggaaac
     1441 attgatgttc aggctatgcg cgttcatgtc cggagctaac atgaagcgat caatgggcgc
     1501 caccagcctg gtctatccga acccggtatt cctgataggc acttacgacg agaagggtca
     1561 gccgaacctg atgaccgcgg cctgggccgg gatctgc
//
LOCUS       DAOPZI010000073         1539 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_127174_length_1539_cov_7.566712, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000073 DAOPZI010000000
VERSION     DAOPZI010000073.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1539)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_127174_length_1539_cov_7.566712"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..711
                     /locus_tag="PKM11_08135"
     CDS             <1..711
                     /locus_tag="PKM11_08135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48511.1"
                     /translation="GFEYLVQHARDLEKHAGKGKAAKDRKLSRGLAMFKKEYLQGDKR
                     SRLLFRRKVSRRFSPLENQEVIDALGEIRRKEGFRRLLLMQDLGDFHAGGKESALASA
                     LSVAGVTVLYGTNNREKDTVEITEKVGEHLYLMNQDLFGFLPHLVTAEELVLFVKNVG
                     SLSALPEPRSSTMVVDLTGGREDEMKTFSDELAKSGTGALFLLDSNVEMRSTLPEGQT
                     ALSFDGKDVSGIVEWLKR"
     gene            968..>1539
                     /gene="gpmA"
                     /locus_tag="PKM11_08140"
     CDS             968..>1539
                     /gene="gpmA"
                     /locus_tag="PKM11_08140"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: protein motif:HMM:NF010713.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HNX48512.1"
                     /translation="MIKVVLLRHGESTWNKENRFTGWTDVGLSDKGVAEAHEAARLLK
                     DGGYEFDIAFTSVLKRAIKTLDIVLEDMDLCWLPVRKSWRLNEKHYGALQGLNKSEMA
                     KKYGEEQVLLWRRAYDVRPPTLELDDPRHPVHDRRYADMATEDIPGTECLKDTVSRFV
                     PYWKEQIVPELKNGKRVIIAAHGNSLRALV"
BASE COUNT          345 a          438 c          465 g          291 t
ORIGIN      
        1 ggattcgagt acctggtcca gcacgccagg gatctggaga agcacgctgg aaaaggaaag
       61 gcggccaagg accgcaagct ctctcgcggc ctggccatgt tcaagaagga atacctccag
      121 ggcgacaagc gctcccgact gctttttcgc agaaaggtta gcaggcgctt cagtccattg
      181 gagaaccagg aggtcatcga cgccctcggt gagatcaggc gcaaggaagg gttccgccga
      241 ctgctcttga tgcaggacct gggcgacttc catgccggag gaaaggagag cgctctggcc
      301 tccgcgcttt cggtggccgg ggtcaccgtt ctctacggca cgaacaaccg agagaaggat
      361 acggtggaga tcactgagaa ggttggcgag cacctctatc ttatgaacca ggacctattc
      421 gggttcctgc cgcacctggt cacggccgag gagctggtcc tgttcgttaa gaacgtggga
      481 tccctgagcg cccttcccga gccgagatct tccaccatgg tggtcgacct caccggcggc
      541 cgcgaggacg aaatgaagac gttctcggat gagctagcca agagcggaac cggagcgttg
      601 ttcctattgg acagcaatgt ggagatgcga tccacactgc ctgaagggca gacggccctg
      661 tcgttcgatg gcaaggacgt ctccggcatc gtggaatggc tcaaacggta gcggatcacc
      721 tcttcctcac catctgcaac gccagcacga ttaccagtat cagtatgacg tacccgatca
      781 tggcgtccag cttggcgtcc gtcgcctacc gcgacaccta agctcaccgg cgctccagct
      841 gaaggatcag atacttgatg ccgagcagca tgatcgatgg cgatcctctt tcaataattc
      901 gcccgcgtcc tggctgaaag cgggcgaaac tgtttttatc gtcggccaac atgtactatc
      961 gactaaaatg atcaaggtcg tactgctacg tcacggggag agcacctgga acaaggagaa
     1021 ccgcttcacc ggctggaccg acgtcggtct ctccgacaag ggcgtggcgg aggcgcacga
     1081 ggccgcccgt cttctgaagg acggcggtta cgagttcgat atcgcattta cttccgttct
     1141 gaaaagagcg atcaagaccc tggacatcgt cctggaggac atggacctgt gctggctccc
     1201 ggttcggaaa tcatggcgcc tcaacgagaa gcattacggt gcgctgcaag gcctgaacaa
     1261 atcggagatg gccaagaagt acggcgagga acaggtgttg ctgtggcgcc gggcctacga
     1321 cgttcgaccg ccaacgttgg agctggacga tccccgtcac cccgtgcatg accggcgtta
     1381 cgcggacatg gccacggaag acataccagg caccgaatgc ctgaaggata ccgtttctcg
     1441 tttcgtacct tattggaagg agcagatcgt tccggaactg aagaacggca agcgggtcat
     1501 catcgccgcc cacggcaatt cgctgcgggc gttggtcaa
//
LOCUS       DAOPZI010000074         1523 bp    DNA     linear   ENV 07-JUN-2024
DEFINITION  MAG TPA_asm: Methanomassiliicoccales archaeon isolate AMR_MDS_1292
            NODE_129283_length_1523_cov_6.320163, whole genome shotgun
            sequence.
ACCESSION   DAOPZI010000074 DAOPZI010000000
VERSION     DAOPZI010000074.1
DBLINK      BioProject: PRJNA925477
            BioSample: SAMN32854497
            Sequence Read Archive: SRR4236661
KEYWORDS    WGS; ENV; Metagenome Assembled Genome; MAG; Third Party Data; TPA;
            TPA:assembly.
SOURCE      Methanomassiliicoccales archaeon (wastewater metagenome)
  ORGANISM  Methanomassiliicoccales archaeon
            Archaea; Candidatus Thermoplasmatota; Thermoplasmata;
            Methanomassiliicoccales.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Abdulkadir,N., Saraiva,J.P., Zhang,J., Stolte,S., Gillor,O.,
            Harms,H. and Rocha,U.
  TITLE     Genome-centric analyses of 165 metagenomes show that mobile genetic
            elements are crucial for the transmission of antimicrobial
            resistance genes to pathogens in activated sludge and wastewater
  JOURNAL   Microbiol Spectr 12 (3), e0291823 (2024)
   PUBMED   38289113
REFERENCE   2  (bases 1 to 1523)
  AUTHORS   Abdulkadir,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2023) Environmental Microbiology, Helmholtz
            Center for Environmental Research -UFZ, Permoserstr 15, Leipzig
            04318, Germany
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: SPAdes v. 3.11.1
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: Not Applicable
            Sequencing Technology  :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 05/03/2023 02:02:41
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline (PGAP)
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS-2+
            Annotation Software revision :: 6.5
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                :: 1,630
            CDSs (total)                 :: 1,585
            Genes (coding)               :: 1,585
            CDSs (with protein)          :: 1,585
            Genes (RNA)                  :: 45
            rRNAs                        :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs               :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                        :: 40
            ncRNAs                       :: 1
            Pseudo Genes (total)         :: 0
            CDSs (without protein)       :: 0
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Methanomassiliicoccales archaeon"
                     /mol_type="genomic DNA"
                     /submitter_seqid="NODE_129283_length_1523_cov_6.320163"
                     /isolate="AMR_MDS_1292"
                     /isolation_source="Activated sludge of municipal
                     wastewater treatment plants"
                     /db_xref="taxon:1906667"
                     /environmental_sample
                     /geo_loc_name="Japan"
                     /lat_lon="35.92 N 139.63 E"
                     /collection_date="2015-05-17"
                     /metagenome_source="wastewater metagenome"
                     /note="metagenomic"
     gene            <1..665
                     /locus_tag="PKM11_08145"
     CDS             <1..665
                     /locus_tag="PKM11_08145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HNX48513.1"
                     /translation="YQLIISDGNSTGVIASDDPFEVSENGTVIECNVTEHLMVRFLPQ
                     VAHRHQWMEMVLMQAVQEGRVAAEITLVGDDGSGIYDTVSYRQEMNVQVQQVVKNKFK
                     FMAQGENAQGALMLVHTESGTMDMSRDRLQVRLNDQDMRYTDDPLELLYGQPEDACYT
                     VIDDGEVQQMLVYLPANSLGAITVESVDPLAALFSPAGIAIMVGALALVALAGVVAFR
                     KR"
     gene            complement(695..>1523)
                     /locus_tag="PKM11_08150"
     CDS             complement(695..>1523)
                     /locus_tag="PKM11_08150"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025025.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HNX48514.1"
                     /translation="CLRSLSSQKLKGKELVEMLVISSGSVDRTDELVLEYARDVDPRV
                     RLIRQEKREGKNSAVNAFIEAAKGDVLFLANADNVMLDDTFDLMAEHFLDPTTGMVGG
                     HPVPVNDKNTFMGFAVHMLWDMHHRLSLIHPKVGEIVAFRNTGLRIPVGMGSDEDLIR
                     KDMEGRGLLVKYEPSAMIYNRGPTNVEDFFEQRTRVNIGERYMKRWFDYDIPTWDKRY
                     LFSAYLSFLKDNANHPLKMAWAMSLEAVARIYASVHVRLDKGDRAVWQVVQSTKDVK"
BASE COUNT          295 a          469 c          442 g          317 t
ORIGIN      
        1 cctaccagct gatcatctcc gacggaaatt ccaccggggt catcgcctcc gacgatccgt
       61 tcgaggtgtc ggagaacggg acggtcatcg agtgcaacgt gaccgaacat ctcatggtac
      121 gcttcctgcc gcaggtggcc caccgccacc agtggatgga gatggtcctc atgcaggccg
      181 ttcaagaggg acgcgtagcc gcggagatca ccctggtcgg agatgacggg agcggcatct
      241 acgacaccgt ctcctatcgc caggagatga acgtgcaggt ccagcaggtc gtgaagaaca
      301 agttcaagtt tatggcccag ggcgagaacg cccagggcgc cctgatgctg gtccataccg
      361 aatccggcac catggacatg tctcgtgacc gtctccaggt acgcctgaac gatcaggaca
      421 tgcgatacac cgatgatccg ttggagctcc tgtatggaca gcctgaggac gcctgctaca
      481 ccgtgatcga cgatggcgag gtgcaacaga tgctggtcta tctgccggcc aactctctgg
      541 gtgccatcac cgtcgagagc gtcgaccccc ttgccgcgct gttctctccg gccggcatag
      601 ccataatggt cggcgccctg gccctggtgg ccctggccgg agtggtggcc ttcaggaaga
      661 ggtgagcgaa ctctcccaaa cctcttccta ttttttattt gacgtccttg gtgctctgca
      721 caacttgcca caccgcccgg tcccccttgt ccagacggac atggacggac gcatagatcc
      781 tggcgacggc ctccagggac atggcccagg ccatcttcaa cgggtggttg gcgttgtcct
      841 tgaggaagct gaggtaggca ctgaacaggt aacgcttgtc ccaggtcgga atatcataat
      901 cgaaccacct cttcatgtac cgttccccga tgttgacacg ggtgcgctgc tcgaagaagt
      961 cctcgacgtt cgtgggaccg cggttgtata tcatggccga cggttcgtac ttgaccagca
     1021 accctcgacc ttccatgtcc ttccgtatga ggtcctcgtc gctgcccatg cccaccggta
     1081 tgcgcagccc ggtgttacgg aaggcgacta tctccccgac cttggggtgg atcagggaca
     1141 atcgatgatg catgtcccag agcatgtgca cggcgaagcc catgaaggtg ttcttgtcgt
     1201 taaccggaac cggatgaccg cccaccattc ccgttgtggg atcgaggaag tgctcggcca
     1261 tcagatcgaa tgtgtcatcc agcatcacgt tgtcggcgtt ggccaaaaag agcacatcgc
     1321 ccttggccgc ctctatgaac gcgttcacgg cggagttctt gccctcccgc ttctcctgcc
     1381 tgatcagacg gacccgggga tcgacgtccc tggcgtattc gagcaccagc tcgtcggtgc
     1441 ggtcgacgct gccgctagag atgaccagca tctcaaccag ctcctttcct ttgagcttct
     1501 gtgagctgag ggagcgcagg cac
//
